bluuebunny/crossref_metadata_2025 huggingface dataset:
Fine mapping of candidate regions associated with fat deposition in thin and fat tail sheep breeds suggests new insights into molecular aspects of fat tail selection
Authors: Moradi Mohammad Hossein , Nejati-Javaremi Ardeshir , Moradi-Shahrbabak Mohammad , Dodds Ken G. , Brauning Rudiger , McEwan John C.
Published: August 2021

Background

Fatness related traits are economically very important in sheep production and are associated with serious diseases in humans. The fat tail is a phenotype that divides domesticated sheep into two major groups. The objective of the present study is to refine the map location of candidate regions associated with fat deposition, obtained via two separate whole genome scans contrasting thin and fat tail breeds, and to determine the nature of the selection occurring in these regions using hitchhiking approach.
Results

Zel (thin tail) and Lori-Bakhtiari (fat tail) breed samples that had previously been run on the Illumina Ovine 50k BeadChip, were genotyped with a denser set of SNPs in the three candidate regions using a Sequenom Mass ARRAY platform. Statistical tests were then performed using different and complementary methods based on either site frequency (FST and Median homozygosity) or haplotype (iHS and XP-EHH). Results from candidate regions on chromosome 5 and X revealed clear evidence of selection with the derived haplotypes that were consistent with selection to near fixation for the haplotypes affecting fat tail size in the fat tail breed. Analysis of the candidate region on chromosome 7 indicated that selection differentiated the beneficial alleles between breeds and homozygosity has increased in the thin tail breed which also had the ancestral haplotype. These results enabled us to confirm the signature of selection in these regions and refine the critical intervals from 113kb, 201kb and 2,831kb to 28kb, 142kb and 1,006kb on chromosome 5, 7 and X respectively. These regions contain several genes associated with fat metabolism or developmental processes consisting TCF7 and PPP2CA (OAR5), PTGDR and NID2 (OAR7), AR, EBP, CACNA1F, HSD15B, SLC35A2, BMP15, WDR13 and RBM3 (OAR X), each of which could potentially be the actual target of selection. Study of core haplotypes alleles in our regions of interest also supported the hypothesis that the first domesticated sheep were thin tailed and fat tail animals were developed later.
Conclusions

Our results provide a comprehensive assessment of how and where selection has affected the patterns of variation in candidate regions associated with fat deposition in thin and fat tail sheep breeds. The hitchhiking mapping approach in this study was novel in the sense that most of the exploratory genome scan studies in domestic animals have not clarified the signal from the candidate regions, probably due to the lack of suitable genomic resources.
Formation of core-shell droplets for the encapsulation of liquid contents
Authors: Galogahi Fariba Malekpour , Zhu Yong , An Hongjie , Nguyen Nam-Trung
Published: August 2021

Accurate control of monodisperse core-shell droplets generated in a microfluidic device has a broad range of applications in research and industry. This paper reports the experimental investigation of flow-focusing microfluidic devices capable of producing size-tuneable and monodisperse core-shell droplets. The dimension of the core-shell droplets was controlled passively by the channel geometry and the flow rate of the liquid phases. The results indicate that microchannel geometry is more significant than flow rates. The highly controllable core-shell droplets could be subsequently employed as a template for generating core-shell micropaticles with liquid core. Optical, electron microscopy and X-ray computed microtomography showed that the geometry of the core-shell droplets remains unchanged after solidification, drying and collection. The present study also looks at the thermal stability of core-shell particles depending on the particle size. The larger core-shell partcles with a thicker shell provide a higher resistance to heating at elevated temperature. The high degree of control with a flow-focusing microfluidic device makes this a promising approach for the encapsulation, storage, and delivery of lipophilic contents.
An improved 4D trajectory modeling approach for traffic management
Authors: Shen Zhou , Yu Xiaomo
Published: August 2021

Under the premise that the capability of existing air transportation system can no longer meet the demand of air traffic flow, 4D trajectory operation based on accuracy is the basis of future air traffic management (ATM) system to achieve the optimization of flight trajectory. This article investigates the establishment of a data model system based on aircraft performance and operation procedures, which can be applied to 4D trajectory prediction to greatly reduce or avoid the possibility of flight conflicts in the air, enhance air traffic safety and improve air traffic flow.
Diversity, friction, and harmonisation: An ethnographic study of interprofessional teamwork dynamics
Authors: Skyberg Henriette Lund
Published: August 2021

Background: Although diversity, friction, and harmonisation in interprofessional teamwork are aspects frequently conceptualised, no empirical studies discuss them in combination. Focusing on risk and function with respect to each aspect, this paper examines how dynamics between these aspects during interprofessional teamwork interactions can foster (ideal) conditions for productive teamwork.Methods: An ethnographic study of three interprofessional teams in a mental health and substance use context in Norway, was conducted. Data were collected through observations of 14 team meetings and 18 in-depth interviews with health and social work professionals. Thematic analysis was applied to code the data.Results: A conceptual ideal-type model, which includes all three aspects, was developed to represent the emergent findings. The results suggest that the diversity of professional perspectives inherent in interprofessional teams is the foundation of interprofessional teamwork. However, friction is needed to promote innovation, encourage new insights, and intensify discussions. Harmonisation balances professional distinctions, fosters trust, and ties professionals together.Conclusion: This paper presents a comprehensive model of how professionals work together in interprofessional teams that makes visible the functions and risks of each aspect and the dynamics between them. Furthermore, it argues for mobilising all three aspects in combination during interprofessional teamwork to maximise productivity. Such insight can be used to support the development and successful implementation of interprofessional teamwork in health care.
Proving the 6d Cardy formula and matching global gravitational anomalies
Authors: Chang Chi-Ming , Fluder Martin , Lin Ying-Hsuan , Wang Yifan
Published: August 2021

A Cardy formula for 6d superconformal field theories (SCFTs)
conjectured by Di Pietro and Komargodski in [1] governs the universal
behavior of the supersymmetric partition function on
S^1_\beta \times S^5Sβ1×S5
in the limit of small \betaβ
and fixed squashing of the S^5S5.
For a general 6d SCFT, we study its 5d effective action, which is
dominated by the supersymmetric completions of perturbatively
gauge-invariant Chern-Simons terms in the small
\betaβ
limit. Explicitly evaluating these supersymmetric completions gives the
precise squashing dependence in the Cardy formula. For SCFTs with a pure
Higgs branch (also known as very Higgsable SCFTs), we determine the
Chern-Simons levels by explicitly going onto the Higgs branch and
integrating out the Kaluza-Klein modes of the 6d fields on
S^1_\betaSβ1.
We then discuss tensor branch flows, where an apparent mismatch between
the formula in [1] and the free field answer requires an additional
contribution from BPS strings. This ``missing contribution’’ is further
sharpened by the relation between the fractional part of the
Chern-Simons levels and the (mixed) global gravitational anomalies of
the 6d SCFT. We also comment on the Cardy formula for 4d
\mathcal{N}=2𝒩=2
SCFTs in relation to Higgs branch and Coulomb branch flows.
Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
Authors: Chazin Eliza , Martins Leonardo , de Souza Marcus Vinícius , Gomes Claudia Regina , da Silva Ana Cláudia , Branco Marcelly , Sanchez Eladio , Fuly André , Vasconcelos Thatyana
Published: August 2021

This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of their ability to inhibit some in vitro (coagulant, proteolytic and hemolytic) and in vivo (hemorrhagic, edematogenic and lethality) toxic activities of Bothrops jararaca and Bothrops jararacussu venoms. Compounds have been synthesized from the coupling of intermediate 5-amino-6-methoxybenzo[d] [1,3]oxathiol-2-one 4 with benzenesulfonyl chlorides. Characterization of the products was achieved by nuclear magnetic resonance (NMR) and electrospray ionization mass spectra (ESI-MS) techniques. Biological assay results have shown that most of compounds inhibited the main toxic activities of the venom of the two snake species. Compound 5b (N-(6-methoxy-2-oxobenzo[d] [1,3]oxathiol-5-yl)-4-nitrobenzenesulfonamide) was the most efficient in inhibiting hemolysis of B. jararaca, and coagulation and proteolysis induced by both venoms. For in vivo activities, all compounds inhibited the edema, from 35 to 72%, and most of them exhibited antihemorrhagic and antilethality activities. Thus, the results pointed to the biological potential of these compounds, being promising molecules to treat envenomation by these snakes as well as to aid the current antivenom serum therapy.
Quantitative assessment of hydrological alteration over multiple periods caused by human activities at the Jingjiang Three Outlets, China
Authors: Wang Hongxiang , Zhu Yongwei , Jin Yaoguang , Guo Wenxian
Published: August 2021

The Jingjang Three Outlets (JTO) play a major role in the water-sediment transport from the Yangtze River to Dongting Lake. The hydrological regimes at the JTO (Songzi, Taiping, and Ouchi) had been changed due to the Jingjiang Cutoffs (JC), the Gezhou Dam (GD), and the Three Gorges Dam (TGD). Based on hydrological data from 1955 to 2019, the variation trend in annual streamflow was detected using three techniques, and the hydrological alteration was assessed with the Range of Variability Approach. Conclusions are as follows: (1) the inflection points consistent with human activities and the time series were divided into periods of P1 (1955–1971), P2 (1972–1985), P3 (1986–2002), and P4 (2003–2019); (2) human activities made a greater contribution to streamflow change than climate change; (3) the hydrological alteration degree caused by the JC, GD, and TGD projects were 56%, 47%, and 52% at the Songzi outlet; 57%, 41%, and 57% at the Taiping outlet; and 57%, 41%, and 57% at the Ouchi outlet; and (4) the ability of division from the Yangtze River to Dongting Lake is weakening and the hydrological regimes at the JTO are deteriorating due to the JC, GD, and TGD, resulting in negative impacts on the biotic composition, structure, and function of riparian ecosystems. This study provides useful insight for ecosystem protection under hydrological alteration.
Challenges facing the management of wastewater treatment systems in Chinese rural areas
Authors: Liang X. , Yue X.
Published: August 2021

The water environment in Chinese rural areas has seriously deteriorated to the extent that the development of rural areas is now under threat. To deal with this issue, the Chinese government has been promoting wastewater treatment systems (WTS) in rural areas since 2005. However, some of these wastewater treatment plants have shut down after just a few years. Thus, even though the number of newly built plants in rural areas has been rapidly increasing, the failure of these plants can impede the development of an efficient wastewater treatment in Chinese rural areas. This paper investigates the challenges faced by the management of the constructed wastewater treatment plants in Chinese rural areas using the case study method. Two cases, of Zhejiang and Hainan provinces, were analysed separately; the operation was successful in the former province and a failure in the latter one. The study demonstrates that the WTS in rural areas are faced with diverse implementation challenges, ranging from unsustainable financial sources for operation and maintenance cost to inappropriate governance structure, potential risks due to the local leadership rotation system of the government, limited participation by farmers in the management and technical complexity.
La proyección social una apuesta desde el acompañamiento pedagógico
Authors: Giraldo-Gómez Olga , Zuluaga-Giraldo Jorge Iván , Naranjo-Gomez Dulfari
Published: August 2021

La Universidad Católica de Manizales, en coherencia con su sueño institucional de “forjar día a día, hombres y mujeres integrales, líderes constructores de una nueva humanidad”, le apuesta al mejoramiento de la calidad de vida de las poblaciones más vulnerables. De este modo, hace presencia en la Fundación Niños de los Andes de Manizales, con un equipo de docentes y docentes en formación de los programas de licenciatura de la Facultad de Educación, con el objetivo de contribuir al desarrollo integral de los niños y jóvenes, con base en el apoyo y acompañamiento pedagógico en las áreas de Lectoescritura y Tecnología e Informática. Este ejercicio se desarrolla a través de diferentes momentos que posibilitan la puesta en marcha de prácticas pedagógicas con un alto sentido social. De esta manera se procura el desarrollo de habilidades lectoescriturales, mediante diferentes estrategias. Simultáneamente, se incentiva el uso apropiado de diversos recursos didácticos mediados por la tecnología, lo cual redundará en un mejor desempeño académico y social por parte de la población de los Niños de los Andes.
Consideraciones sobre el sentido del juego en el desarrollo infantil
Authors: Mieles-Barrera María Dilia , Cerchiaro-Ceballos Elda , Rosero-Prado Ana Lucia
Published: August 2021

La creciente visibilización de la niñez ha permitido comprender mejor su complejidad y los profundos desafíos que plantea al mundo adulto. En este artículo se aborda críticamente el papel del juego como medio para promover el desarrollo y la educación en la infancia. Se discute el alcance de los Derechos del Niño, en tanto las familias, las comunidades y el Estado tienen limitaciones en la transformación de situaciones estructurales que obstaculizan su pleno ejercicio. De los Derechos del Niño se aborda uno que debería ser de elemental cumplimiento: el derecho al juego –al juego libre–. En este sentido, se revisan los beneficios que esta actividad ofrece al desarrollo infantil, al tiempo que se plantean algunas limitaciones y obstáculos para su práctica efectiva.
The Impact of the Use of C-Arm Cone-Beam CT During Chemoembolization for Hepatocellular Carcinoma
Authors: Abdelsalam Mohamed E. , Figueira Tomas M.A. , Ensor Joe , Tam Alda L. , Avritscher Rony , Kaseb Ahmed , Gupta Sanjay
Published: August 2021

Objective:

The objective of the study was to investigate the consequences of using CArm
Cone-Beam computed Tomography (CBCT) on super-selective catheterization of Hepatic
Artery (HA) branches during chemoembolization of hepatocellular carcinoma.

Methods:

Two groups of patients were created according to the dates of their treatment sessions.
Group A and Group B included patients who had their treatment sessions in 2004 - 2005 and 2008
- 2010, respectively. The sessions performed in 2006 and 2007 were excluded to allow for the adoption
and incorporation of CBCT imaging into clinical practice. All chemoembolized HA branches
were categorized according to selection order (0-1, 2, or ≥3). Other procedure variables were documented.

Results:

A total of 58 and 183 sessions were included in Groups A and B, respectively, for 144 patients.
C-arm CBCT was used in 2 (3%) sessions and 142 (78%) sessions in groups A and B, respectively.
The average number of vessels treated was significantly higher in group B (1.8) compared
to group A (1.3) (P < .0001). A shift to an increased selection order in group B (0-1, 44
[24%]; 2, 85 [46%]; ≥3, 54 [30%]) was more significant (P = .0004) than that in group A (0-1, 32
[55%]; 2, 18 [31%]; ≥3, 8 [14%]). The average duration of the procedure was significantly longer
in group B (P = .0002).

Conclusions:

Using C-arm CBCT during chemoembolization has a positive impact on increasing
the number and order of HA selected and chemoembolized. This comes at the expense of an increase
in the duration of the procedure.
Recent Advancement on Ferrite Based Heterojunction for Photocatalytic Degradation of Organic Pollutants: A Review
Authors: Shandilya P.
Published: August 2021

The progress of ferrites and ferrites-based nanocomposites has become extensively popular in the field of photocatalytic wastewater treatment. This class of compound exhibit several fascinating properties related with their high stability, low cost, ease of functionalization, and biocompatibility. Ferrites carry outstanding magnetic behavior that helps in their easy recovery from the aqueous system thus reducing the cost. The morphology and various properties such as magnetic, absorption, optoelectronic of magnetic ferrites can be varied and optimize by applying different synthetic routes and reaction conditions. With this background we have briefly presented and reviewed the latest development in the field of photodegradation of aqueous pollutants using ferrites based heterojunction. Especially, the type-II, Z-scheme and S-scheme based heterojunction for enhanced pollutant degradation under the exposure of light are thoroughly describe. Ferrites have inherent potential in water remediation applications hence many examples were consider to impart valuable knowledge to the readers. Nevertheless, the large-scale utilization of these magnetic nanoparticles still needs to be explored. Therefore, the gaps, challenges and future prospective of ferrites nanoparticles are also explained to unveil the un-scrutinized standard of ferrites nanoparticles.
Differences in acute childhood poisoning: A single center experience
Authors: TÜRKMENOĞLU Yelda , KAÇAR Alper , TERLEMEZ Belen , GÜVENER Gizem , BÜTÜN Pınar , YOLGİDEN GUREN Seda , AKŞAHİN Berna , SARITAŞ Ümit , IRDEM Ahmet , BESER Faruk
Published: August 2021

Introduction: Characteristics of acute childhood poisonings may change over time in the same populations. The aim of this study is to compare the demographic characteristics of poisoning children presenting to the same center at different times.Methods: This study was conducted among children aged 0-16 years who presented with the complaint of poisoning to our center in 2010 and 2016.The demographic characteristics of the poisoning cases were evaluated from the emergency records and the findings of both years were compared with each other. Results: The mean age of 404 cases in Group 2010 and 398 cases in Group 2016 were 6.5 ± 5.1 years and 4.7 ± 4.6 years, respectively (p = 0.001). Drug poisonings were in the first place in both groups, the group was 61.6% in 2010 and 49.7% in 2016 (p = 0.001). Gas poisoning was observed at a rate of 19.2% in the Group 2010 and 10.1% in the Group 2016 (p = 0.0001). When Group 2010 and Group 2016 were compared, poisoning with corrosive substances was observed with a frequency of 13.8% in Group 2010 and 29.4% in Group 2016. The rate of accidental poisoning cases was 77.3 % in Group 2010 and 81.9 % in Group 2016 (p = 0.001). Conclusions: There was a decrease in drug and gas intoxications, but an increase in intoxications with caustic substances. It is thought that the increase in accidental poisoning can be prevented by increasing the awareness and education of the society on this issue.
PERFORMANCE EVALUATION OF THE VEGETABLE TRADING CENTER IN LANTAPAN, BUKIDNON, PHILIPPINES
Authors: Cosrojas Karen Debbie Jabenar
Published: August 2021

This paper evaluated the performance of the project: “Farmer Cluster-Managed Bagsakan (trading center) Model in Lantapan, Bukidnon”. It used the CIPP and OECD-DAC evaluation frameworks to make sense of the data. The said project envisioned to operate a farmer-cluster managed bagsakan center. The bagsakan was operationalized and result shows that farmers derived higher profit when they brought their products in the center compared to marketing it to major cities. Other outputs of the project are the trainings conducted but these did not reflect significant contribution to the bagsakan operation. In terms of the relevance of the project, its objective is found valid because it answers to the needs and problems confronting the vegetable farmers. Effectiveness assessment tells that to a little extent the project’s objective was attained given the bagsakan’s operationalization. Sustainability measurement of the project was not realized since the operation only lasted for one year.
THE INFLUENCE OF ORGANIZATIONAL CULTURE, EMPLOYEE EMPOWERMENT AND JOB SATISFACTION ON ORGANIZATIONAL COMMITMENTS
Authors: Wahyudin Isya , Hadjar Ismu , Yusnita Nancy
Published: August 2021

Organizational commitment is the willingness of someone who is in an organization to obey, respect and live the values set by the organization, and the main purpose of organizational commitment is to foster a loyal attitude to the organization. This study aims to empirically reveal the influence of organizational culture, employee empowerment and job satisfaction on organizational commitment with the object of employee research at CV. Tirta Usaha Bogor and a total sample of 140 respondents using path analysis. CV. Tirta Usaha Bogor is a distribution company for bottled water products with Aqua and Vit brands. The results show that organizational culture directly affects organizational commitment with a coefficient of 0.31, employee empowerment directly affects organizational commitment with a coefficient of 0.32, and job decision directly affects organizational commitment with a coefficient of 0.19. Commitment to the organization that occurs at CV. Tirta Usaha Bogor is currently strong enough, even with the conditions of organizational culture, empowerment and job satisfaction that are in the good enough category can create commitment to the organization that is good enough to good. If things related to organizational culture, employee empowerment and job satisfaction can be improved, it will create a strong commitment to the organization in each employee.
MARKETING OF AGRICULTURAL PRODUCTS IN THE INTERNATIONAL MARKET AND EXCHANGE POLICIES UNDER THE LAWS OF THE WORLD TRADE ORGANIZATION
Authors: Mareeh Hadi Yahya Saleh , Prabakusuma Adhita Sri , Aleryani Rami Abdullah
Published: August 2021

What has been observed in the developing countries' economy is the dominance of hydrocarbons over exports which have reached 98% in recent years. This may have bad consequences in case oil prices collapse of fuel prices, taking into account that these are related to political, economic, and social variables occurring in the world. Besides, hydrocarbons are vital, yet they are on the way to disappearing. The agricultural sector is one of the most important ones that developing owns, and that is required to develop its way and means of production, which contributes to the development of Middle East countries exports outside hydrocarbon. The most important products are dates, olives, citrus, potatoes, tomatoes, carrots, grapes, and apricots. These products are considered the most important products that can contribute to the development of exports outside hydrocarbons.
Musculocutaneous nerve as a branch from median nerve: A case report
Authors:   Department of Anatomy, College of Medicine, King Saud University, Riyadh, Saudi Arabia, Almatrafi Tahani
Published: August 2021

The brachial plexus is the most variable part of the peripheral nervous system. The Musculocutaneous nerve is a terminal branch of the lateral cord of the brachial plexus in a normal individual. It is not uncommon for variations in the origin, branching termination, and connection patterns. During routine dissection in the Anatomy Department, College of Medicine, King Saud University, we found the lateral cord after giving a small branch to the coracobrachialis muscle join the medial root of the medial cord to form the median nerve. Knowledge of these variations is essential for anatomists, orthopedics, neurologists, and anesthesiologists.
Redes de apoyo a familias en Tunja durante la pandemia: una respuesta ante la crisis generada por la COVID-19
Authors: Bautista-Joaqui Haider Esteban , Franco Riaño Junior Adrián , Mendivelso Vargas Leidy Johana
Published: August 2021

Objetivo. La presente investigación tiene como objetivo conocer las redes de apoyo presentes en familias de Tunja durante la pandemia generada por la COVID-19, así como indagar qué es para las familias una red de apoyo e identificar cuáles son las redes de apoyo y el tipo de apoyo que ellos consideran que deberían estar más presentes en tiempo de pandemia. Método. Se desarrolla bajo un enfoque mixto, para obtener mayor detalle en la información recolectada mediante el uso de una encuesta que fue aplicada en un formulario creado en Google Forms y compartido mediante redes sociales a través de un muestreo por conveniencia a 119 familias de la ciudad de Tunja, con diversas características sociodemográficas, donde sus jefes de hogar oscilaban entre los 19 y 65 años y se encontraban entre estratos socioeconómicos del 1 al 5. Resultados. Los principales hallazgos evidencian que, durante la pandemia, las principales redes de apoyo a familias tunjanas son otros familiares y amigos. El apoyo que más recibieron es el emocional, resultados que concuerdan con las demandas de los mismos participantes en situaciones similares. Las familias participantes le asignan el significado al termino red de apoyo, muy ligado a las características de una red informal. Más de la mitad de la muestra desconoce redes de apoyo a familias, y mencionan con mayor frecuencia a instituciones religiosas y organizaciones gubernamentales.
Variación del nitrógeno ureico en leche según la temporada del año y días en leche
Authors: Tarazona-Manrique Luis Edgar , Andrade-Becerra Roy José , Archila-Barrera Omar Alexander
Published: August 2021

Objetivo. Determinar la variación de NUL según las temporadas del año (época de lluvia y seca) y los días en leche (DEL) de vacas lecheras de dos ganaderías en el altiplano boyacense de Colombia. Materiales y métodos. Se realizó un estudio de tipo descriptivo cuantitativo por conveniencia. Se incluyeron 4.901 muestras de leche de 112 animales ubicados a una altura de 2600 msnm durante un período de 24 meses, agrupando las muestras de acuerdo con la temporada y los días en producción de leche. Las muestras fueron procesadas a través de metodología enzimática espectofotométrica para la determinación del NUL. Se realizó un análisis de varianza para los grupos por temporada climática, mientras que para los días en leche se hizo una descripción cuantitativa. Resultados. El NUL varió según la temporada del año (p<0.05), siendo mayores los valores durante la época lluviosa. El NUL fue menor durante los primeros 60 DEL en la mayoría de los grupos conformados y los picos se presentaron a partir de los 180 DEL. Los menores valores de NUL de acuerdo a los días en leche se determinaron en los primeros 60 días en la mayoría de los grupos conformados, así mismo los principales picos se determinaron a partir de los 180 DEL. Conclusiones. El NUL varió de acuerdo con la temporada siendo más alto en lluvias, el NUL fue menor durante los primeros 60 DEL en la mayoría de los grupos conformados y los picos se presentaron a partir de los 180 DEL.
Triple Viral Infections in The Same Cats: Feline Coronavirus, Feline Parvovirus, Feline Foamy Virus
Authors: Oguzoglu Tuba Cigdem , KOÇ B. Taylan , Akkutay-Yoldar Zeynep
Published: August 2021

Objective. Several studies from different countries have been performed about the viral diseases of domestic cats, and detailed information has been provided on their transmission, prevalence/incidence, virulence, origins/molecular characteristics and pathogenesis so far. Multiple- or co-infections in domestic and wild cats have been described by many papers. However, viral co-infections have been reported on a limited basis. In this study, three domestic clinically diseased cats have been found to be positive with feline coronavirus (FCoV), feline parvovirus (FPV) and feline foamy virus (FFoV). We aimed to examine triple viral infections circumstances in Turkish cats. Material and method. Ascites and blood samples were collected from diseased cats. Different polymerase chain reaction protocols for each virus were performed. After PCRs, all products were run in agarose gel and visualized under a blue-light transilluminator. Results. We found FCoV, FPV and FFoV as triple infection in three cats. Conclusions. We think that the results indicating the presence of multiple infections will ease the work of veterinary clinicians concerning infection treatment options, especially when animals show multiple clinical findings due to co-infections. It should be not forgotten the presence of multi-systemic co-infections in early routine laboratory diagnosis.
Hearing Assessment in Adult Patients with Common Variable Immunodeficiency
Authors: Aytekin Gökhan , Çölkesen Fatih , Yıldız Eray , Arıcıgil Mitat , Arslan Şevket
Published: August 2021

ABSTRACT Objective: Common Variable Immunodeficiency (CVID) is a primary antibody disorder characterized by impaired B cell differentiation. Patients commonly present with acute and chronic sinusitis as well as otitis media, which may lead to hearing loss. Materials and Methods: Thirty-three CVID patients (20 male /13 female) with a mean age of 35 years (range 19-65 years) and 33 healthy individuals as a control group were included. Results: Among CVID patients, 17 (51.5%) had conductive hearing loss (CHL) , being unilateral in 4 (12.1%) and bilateral in 13 (39.4%). Unilateral and bilateral sensorineural hearing loss (SNHL) were detected in 2 (6.1%) and 5 (15.2%) respectively. CD4/CD8 cell ratio was significantly lower while CD8+ T lymphocyte ratio was significantly higher in those with CHL than in those without it (p=0.045 and p=0.009). Elevated CD8+ T cell ratio was an independent risk factor for CHL (p=0.015). Patients with SNHL were significantly older than those without it (p=0.040). CD16-56+ cell count was significantly lower in those with SNHL (p=0.031). Conclusion: CVID patients have an increased occurrence of CHL and SNHL, regardless of the cause. They provide evidence for the notion that these two types of hearing loss are not unrelated, immune dysregulation also plays a role in the process, and SNHL is not independent of CHL. Keywords: Common variable immune deficiency, conductive hearing loss, sensorineural hearing loss
Anxiety and Depression Among Patients with Predominantly Antibody Deficiencies and the Importance of Early Diagnosis
Authors: Yeşillik sait , Demirel Fevzi
Published: August 2021

ABSTRACT Objective: Diagnostic delay is one of the major problems for patients with predominantly antibody deficiencies (PAD) that can lead to anxiety and depression disorders, like in other chronic diseases. We aimed to detect the frequencies of anxiety and depression in PAD patients. The second aim was to determine the influence of diagnosis delay on the patients’ anxiety and depression. Materials and Methods: In this prospective study, 40 patients and 50 healthy controls answered the Hospital Anxiety and Depression Scale (HADS). We compared the anxiety, depression, and the total scores of the patients and the healthy controls. We divided the patients into two groups as delayed and early diagnosed patients according to median diagnostic delay year and compared the HADS scores of the two groups. Results: The anxiety, depression and the total scores of PAD patients were significantly higher compared to the healthy controls; (p=0.001, p=0.001, p=0.001), respectively. The HADS scores were significantly higher in the delayed diagnosis patient group than the early diagnosed patient group (p=0.001, p=0.003, p=0.001), respectively. We also confirmed this positive relationship between delayed diagnosis and the HADS scores with Spearman’s correlation analysis. Conclusion: We demonstrated that psychiatric disorders such as anxiety and depression are common in PAD patients, and delayed diagnosis strongly affects their anxiety and depression. Collaboration with psychologists and psychiatrists during the management of these patients may improve the quality of their life. Keywords: Predominantly antibody deficiencies, early diagnosis, anxiety, depression
The Impact of SARS-CoV-2 Transmission Fear and the COVID-19 Pandemic on the Mental Health of Patients with Primary Immunodeficiency Disorders and Severe Asthma, and Other High-Risk Groups
Authors: Çölkesen Fatih , Kılınçel Oğuzhan , Sözen Mehmet , Yıldız Eray , Beyaz Şengül , Çölkesen Fatma , Aytekin Gökhan , Koçak Mehmet Zahid , Alsancak Yakup , Araz Murat , Arslan Şevket
Published: August 2021

ABSTRACT Objective: The effect of the COVID-19 pandemic on mental health in the long term is unclear. We evaluated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)–related transmission fear and mental-health disorders in populations at high risk for COVID-19. Materials and Methods: Healthcare workers and patients with primary immunodeficiency disorders (PIDs), severe asthma, malignancy, cardiovascular disease, hypertension, and diabetes mellitus were included in the study. The hospital anxiety and depression scale (HADS) and Fear of Illness and Virus Evaluation (FIVE) scales were applied during face-to-face interviews. Results: There was a total of 560 participants, 80 per group; 306 (55%) were female. The FIVE and HADS-A scale scores of health care workers were significantly higher than the other groups (p = 0.001 and 0.006). The second-highest scores were in patients with PID. There was no significant difference between the groups in HADS-D scores (p = 0.07). There was a significant positive correlation between FIVE scale scores and anxiety (r = 0.828; p < 0.001) and depression (r = 0.660; p < 0.001). The FIVE scale had significant discriminatory power for anxiety (AUC = 0.870, 95% confidence interval [CI] = 0.836–0.904; p < 0.0001) and depression (area under the curve = 0.760, 95% CI = 0.717–0.803; p < 0.0001). Conclusion: During the COVID-19 pandemic, mental-health disorders may develop in patients with comorbidities, especially healthcare workers. They should be referred to mental-health centers. Keywords: Asthma, COVID-19, fear of virus transmission, mental health, primary immunodeficiency
Endorsement of Standard Reporting Guidelines by PubMed Indexed Indian Medical Journals (Preprint)
Authors: Mulkalwar Alhad , Gaidhane Purva
Published: August 2021

UNSTRUCTURED

Reporting guidelines have become very important tools in medical research. These guidelines improve the completeness, accuracy and transparency of reporting the crucial aspects of research studies. This aids not only in accurate evaluation of the methodological quality of research and validity of the results, but also improves the quality of evidence synthesized from published data for application in practice.It’s important for the publishers to incorporate these guidelines in their ‘Instructions to Authors’ on the journal website. We documented the extent of endorsement of the five commonly used standard guidelines CONSORT, QUOROM, MOOSE, PRISMA, STROBE and CARE by fifty PubMed indexed Indian Medical journal
Web application to support evidence of individual emotional impact evoked by COVID-19 pandemic restrictions (Preprint)
Authors: Mitre-Hernandez Hugo , Ferro-Perez Rodolfo , Gonzalez-Hernandez Francisco
Published: August 2021

BACKGROUND

Mental health effects during COVID-19 quarantine need to be handled because patients, relatives, and healthcare workers are living with negative emotional behaviors. The clinical disorders of depression and anxiety are evoking anger, fear, sadness, disgust, and reducing happiness. Therefore, track emotions with the help of psychologists on online consultations –to reduce the risk of contagion– will go a long way in assisting with mental health. The human micro-expressions can describe genuine emotions of people and can be captured by Deep Neural Networks (DNNs) models. But the challenge is to implement it under the poor performance of a part of society's computers and the low speed of internet connection.

OBJECTIVE

This study aimed to create a useful and usable web application to record emotions in a patient’s card in real-time, achieving a small data transfer, and a Convolutional Neural Networks (CNN) model with a low computational cost.

METHODS

To validate the low computational cost premise, firstly, we compare DNN architectures results, collecting the floating-point operations per second (FLOPS), the Number of Parameters (NP) and accuracy from the MobileNet, PeleeNet, Extended Deep Neural Network (EDNN), Inception- Based Deep Neural Network (IDNN) and our proposed Residual mobile-based Network (ResmoNet) model. Secondly, we compare the trained models' results in terms of Main Memory Utilization (MMU) and Response Time to complete the Emotion recognition (RTE). Finally, we design a data transfer that includes the raw data of emotions and the basic text information of the patient. The web application was evaluated with the System Usability Scale (SUS) and a utility questionnaire by psychologists and psychiatrists (experts).

RESULTS

All CNN models were set up using 150 epochs for training and testing comparing the results for each variable in ResmoNet with the best model. It was obtained that ResmoNet has 115,976 NP less than MobileNet, 243,901 FLOPS less than MobileNet, and 5% less accuracy than EDNN (95%). Moreover, ResmoNet used less MMU than any model, only EDNN overcomes ResmoNet in 0.01 seconds for RTE. Finally, with our model, we develop a web application to collect emotions in real-time during a psychological consultation. For data transfer, the patient’s card and raw emotional data have 2 kb with a UTF-8 encoding approximately. Finally, according to the experts, the web application has good usability (73.8 of 100) and utility (3.94 of 5).

CONCLUSIONS

A usable and useful web application for psychologists and psychiatrists is presented. This tool includes an efficient and light facial emotion recognition model. Its purpose is to be a complementary tool for diagnostic processes.
Jóvenes en México: ¿existen diferencias entre hombres y mujeres en su inicio sexual y uso del condón?
Authors:   Universidad Nacional Autónoma de México, Menkes-Bancet Catherine , de Jesús-Reyes David ,   Universidad Autónoma de Nuevo León, Sosa-Sánchez Itzel A. ,   Universidad Nacional Autónoma de México
Published: August 2021

El artículo analiza las características del inicio sexual de los jóvenes mexicanos de 12 a 29 años de edad, así como los factores que se relacionan con mayor uso de métodos anticonceptivos, en particular del uso del condón, enfatizando el rol de las desigualdades de género sobre las prácticas sexuales. Se analizó el inicio sexual de los jóvenes en distintos contextos, comparando entre sexos. También se estudió el uso de los métodos anticonceptivos en la primera relación sexual. Para conocer los factores sociodemográficos relacionados con el uso de un preservativo, se estimaron dos modelos de regresión logística estratificados por sexo. Los datos provienen de la Encuesta Nacional de la Juventud 2010.* Los resultados muestran diferencias por sexo tanto en la edad de inicio sexual, como en las características de la pareja y en los significados dados al inicio sexual. Asimismo, los jóvenes con estereotipos de género más tradicionales incrementan la probabilidad de inicio sexualmente a edades más tempranas, y tienen menor probabilidad de protegerse de un embarazo no planeado y de una infección de transmisión sexual.
Development of Hexapod Robot with Computer Vision
Authors: C Abhishek
Published: August 2021

Abstract: Nowadays many robotic systems are developed with lot of innovation, seeking to get flexibility and efficiency of biological systems. Hexapod Robot is the best example for such robots, it is a six-legged robot whose walking movements try to imitate the movements of the insects, it has two sets of three legs alternatively which is used to walk, this will provide stability, flexibility and mobility to travel on irregular surfaces. With these attributes the hexapod robots can be used to explore irregular surfaces, inhospitable places, or places which are difficult for humans to access. This paper involves the development of hexapod robot with digital image processing implemented on Raspberry Pi, to study in the areas of robotic systems with legged locomotion and robotic vision. This paper is an integration of a robotic system and an embedded system of digital image processing, programmed in high level language using Python. It is equipped with a camera to capture real time video and uses a distance sensor that allow the robot to detect obstacles. The Robot is Self-Stabilizing and can detect corners. The robot has 3 degrees of freedom in each six legs thus making a 18 DOF robotic movement. The use of multiple degrees of freedom at the joints of the legs allows the legged robots to change their movement direction without slippage. Additionally, it is possible to change the height from the ground, introducing a damping and a decoupling between the terrain irregularities and the body of the robot servo motors. Keywords: Hexapod, Raspberry Pi, Computer vision, Object detection, Yolo, Servo Motor, OpevCV.
Alert System of Earthquake Detection
Authors: Prakash Surya
Published: August 2021

Abstract: Global warning shows unpredictablenature that changes in subsurface geologicfeatures. Due to the complex nature ofseismic events, it is challengeable task to efficiently identify the prominent features that leads to seismic events. Taking the advantage of availability of Seismic dataset, AI using machine learning is a powerful statistical tools to mitigate these practical challenges for earthquake prediction. The paper focuses on the alert and prediction model of an earthquake using machine learning algorithm. The alert time is a function of distance from epicenter and most alert time is for high magnitude earthquake, because high magnitude earthquake rupture over much larger area and take time to propagate, thus delayed for warning. The main aim of the project is to build precise earthquake prediction model using XGboost regression in machine learning technique. The XGboost regression model implemented on the dataset of 14700 data records. The data is gathered from the Kaggle platform that contains data on events of the earthquake in Indian Subcontinent of 18 years and the last updated is of the year 2018. Tableau 2019 is explored for data visualization of the predicted outcome. The proposed technique is able to give precise prediction of earthquake with sufficient time that will reduce the maximum damages and many lives will be saved. Keywords: Seismic signals, XGboost, Tableau, Prediction.
In-Vivo Pollination; A Better Option for Longevity Test of Pollen Viability of Cowpea (Vigna unguiculata L. Walp)
Authors: S. M. Lawal
Published: August 2021

Abstract: A quick and trusted method for evaluating pollen quality and viability is essential in a conventional breeding program. Techniques used in evaluating pollen viability can be classified into in vivo and in vitro tests. Harrison, Heslop, Harrison and Shivanna (2004) categorize the in vitro test into (a) test of germinability, (b) test of stainability, (c) test for enzyme activity and (d) fluorochromatic procedure (FCR). Using pollen of different age crossability can be suitable in testing pollen viability in the field. This research work was conducted in 2007 and 2008 at the screen house of the Institute for Agricultural Research (IAR) of Ahmadu Bello University Samaru Zaria to study pollen viability and its implication for outcrossing in cowpea. Four genotypes, IT86D1010, IT93K452-1, B301 and kanannado were used in the study. Completely Randomized Design (CRD) was used where each cultivar was sown in four labeled pots containing topsoil mixed with manure and sand. This set of planting was repeated three times but staggered to synchronize the flowering of the genotypes. Pollen grains were collected early in the morning (6:00- 6:30 am) from a matured pollen and kept in a well-labeled Petri dish in a filter paper. The crossing was done immediately after pollen collection at 0 hours, then after 3 hours of collection and 6 hours. The crossing was done in all forms, including reciprocals. Record of successful and failed crosses was taken when pods started to form. A regression analysis of pollen age on percent successful cross was carried out to determine the crossability, pollen viability, and relationships. The study shows that the three varieties, IT86D1010, IT93K452-1 and B301 were readily crossable both as paternal and maternal parents. Kanannado was crossable as a paternal parent only, but no seed was recorded when used as a maternal parent. Regression analysis shows a significant effect of pollen age on pollen viability and crossability. The experiment suggests that pollen from neighboring plants can threaten breeding materials if transferred by an efficient vector since pollen can be viable under ambient temperature for up to three hours. Keywords: In-Vivo, pollen, longevity, cowpea, viability
Formal genus of the value of justice in Indonesia
Authors: Sunaryo Sidik
Published: August 2021

This research aimed to find the formal genus of the value of justice in Indonesia. As known, justice that holds the sense of plurality universally transcends the boundary of formality of narrative texts in a normative way. The plurality of the value of justice that is laden with universality transforms to the genus of the school of thoughts vis-à-vis justice throughout history. Reduced meaning of justice in the perspective and the process of legislation is not powerful enough to negate the genus of justice that inherently represents the fundamental characteristics of justice. The look of the legislative process attractively reflects the genus of hunger for power intended to justify ambitions among factions in the domain of democracy. The formality in the legislation no longer represents the principle of the definition of the legislation and it is getting further away from the reach of the definition of aspiration, let alone to become an inspiration of the objectives of the state as mandated in the constitution. Holistic approach used in this research to find out the formal genus of justice in Indonesia. This research found that religious matters in the legislation-related authorities have become an acceptable ornament among the piles of the works of morality. The integrity that has become the genus of justice morality has transformed into a collection of texts hanging all over the wall of the national parliament. Religions are used as tools of negotiation in the formulation and the making of narrative texts before they are further transformed into legislation. Religions and powers in legislation are competing to find their point of the genus of normativization as expected by each faction. Law came into existence earlier than expected, leaving behind its umbilical cord like a prematurely born soul, the cord through which the values of justice are transferred from its mother, and these values have the dimension of plurality. Law is born, but since it is separable from its genus, it does not carry much of the meaning of birth.