bluuebunny/crossref_metadata_2025 huggingface dataset:
[Retracted] Integrating Intrinsic and Eccentric Seismic Vulnerability Indices to Prioritize Road Network Accessibility
Authors: El Maissi Ahmad Mohamad , Argyroudis Sotirios A. , Kassem Moustafa Moufid , Leong Lee Vien , Mohamed Nazri Fadzli
Published: August 2022

The main aim of this article is to shed light on the establishment of more resilient road networks, which can operate and interact regularly with the surrounding complex‐built environment systems during various natural hazards such as earthquakes. This study is integrating engineering judgment and numerical methods to create a comprehensive evaluation for assessing the accessibility rates for road networks. Moreover, it is validating the significance of integrated seismic assessment on various critical sectors in society, such as improving emergency accessibility and adapting improved mitigation strategies for communities that live in disaster‐prone districts. In this respect, this article investigates the seismic vulnerability assessment results, aiming at underpinning the understanding of road network risks by discussing the main results of the calculated probability of damage for various parameters of the roadway and its assets. A comparative study is performed to study the effect of spatially variable ground motions at different damage states for the main investigated four parameters. These extracted comparative results are used for weighting the main parameters to calculate the intrinsic seismic vulnerability index scores. Furthermore, the eccentric seismic vulnerability index is calculated, by following different steps such as assessing the calculated debris width resulting from the collapsed buildings and extracting the accessibility rates through concluding the effective width values. Subsequently, the variation between the accessibility rates is investigated and the integrated seismic risk assessment for a road system is developed with a focus on the integration between asset damage and functionality by generating integrated heat maps that take into consideration the correlation between all the developed vulnerability indices.
Economic Supply Chain Management System of Farm Products Industry Based on the Belt and Road under the Background of Big Data
Authors: Jiao Jianqiu
Published: August 2022

Under the strategic background of “One Belt, One Road,” the future farm products industry will also become part of the country’s core competitiveness. Promoting the transformation of enterprises in the supply chain is conducive to cultivating the country's core competitiveness and creating good output conditions for China’s manufacturing industry. Under the national strategy of “One Belt, One Road,” the agricultural product industry is facing new development opportunities. This paper analyzes the background, significance, and existing basic problems of the “One Belt, One Road.” Starting from the economic development of the national agricultural product industry, it uses the cluster analysis algorithm to analyze the current overall economic situation of the agricultural product industry and points out the current problems in the industry. The product industry is facing greater pressure for transformation and upgrading. Finally, combined with the strategic background of “One Belt One Road,” from the perspectives of society, government, and enterprises, analyzed its supply chain process, extracted relevant problems, and put forward relevant countermeasures and suggestions from the perspective of intrachain, extrachain, and their interactive integration.
Optimized Neural Network for Research Evaluation of Mineral Resources Carrying Capacity in Southern Shaanxi
Authors: YiCan Li , JunHao Wei , Arshaghi Ali
Published: August 2022

Evaluation of the carrying capacity of mineral resources is one of the important research content in the implementation of sustainable development. Based on analyzing the metallogenic geological characteristics, distribution, and resource status of mineral resources in southern Shaanxi, this paper establishes an analysis model of mineral resources and mineral advantages based on the analytic hierarchy process and applies them to evaluate the advantages of mineral resources. To provide optimal and efficient results, an improved model of an artificial neural network based on the bat optimization algorithm has been utilized. Through model analysis, the potential value and carrying capacity of mineral resources in three major prefecture-level cities in southern Shaanxi are comprehensively evaluated and analyzed. The results show that the main dominant minerals in southern Shaanxi are gold, lead zinc, and molybdenum ore. There are three grades of mineral resources carrying capacity: Shangluo City is an excellent grade, Hanzhong City is a good grade, and Ankang City is a general grade.
[Retracted] Implicit Environmental Injustice in Global Trade: Based on the MRIO Model
Authors: Zhang Ping , Zhang Tianjiao , Meng Ranran , Jiao Shiwen
Published: August 2022

To answer these questions in light of the MRIO model, this paper presents a study of environmental injustice affecting the global economy. Practical ideas and lifespan measurements are often used in studies of the embodied carbon industry. The input‐output table method is an important method for industrial embodied carbon research, which can be divided into the regional input‐output table method, bilateral input‐output table method, and multiregional input‐output table method. Bilateral and multistakeholder consultations are more accurate than regional proposals. Therefore, when studying the carbon industry implied by the two countries, the input‐output table of the two countries is usually used, and the multilateral input‐output table is more reliable for determining the input‐output calculation. Therefore, when studying local problems, it is advisable to adopt a variety of display strategies. The results show that in 2010, the carbon content of the carbon industry was 26,593 thousand tons, down 34.6% from 17,383 thousand tons in 2011, calculated at 2%. From 2012 to 2018, the carbon content grew from 31,051 tons in 2014 to 84,248 tons in 2018, with an average annual increase rate of 18%. The experimental results show that there is a large incidence of carbon emissions in the bilateral trade between China, the United States, and Japan. The expansion of export industries is the main reason for the increase in carbon emissions between the two industries. The role of technology has narrowed this difference to some extent.
The Efficacy of Calcium Carbonate-Vitamin D3 in Pregnant Women for the Prevention of Hypertensive Disorders in Pregnancy
Authors: Chen Zhen , Chen Jing
Published: August 2022

Objective. To evaluate the efficacy of calcium carbonate-vitamin D3 in pregnant women for the prevention of hypertensive disorders in pregnancy. Methods. Between April 2020 and June 2021, 60 pregnant women undergoing prenatal examinations in our hospital were recruited and assigned via the random number table method at a ratio of 1 : 1 to receive conventional pregnancy care (observation group) or conventional pregnancy care plus calcium carbonate-vitamin D3 administration (experimental group). Outcome measures included blood pressure, blood calcium, the occurrence of hypertensive disorders, and adverse events. Results. The diastolic blood pressure (DBP) and systolic blood pressure (SBP) levels at delivery in the experimental group were significantly lower than those in the observation group (

P
<
0.05

). Pregnant women in the experimental group had significantly higher blood calcium levels at labor than those in the observation group (

P
<
0.05

). The administration of calcium carbonate-vitamin D3 resulted in a significantly lower incidence of hypertensive disorders and adverse events versus conventional pregnancy care (

P
<
0.05

). Conclusion. The effect of calcium carbonate-vitamin D3 administration during pregnancy for the prevention of hypertensive disorders is significant, which effectively improves the blood calcium level of pregnant women and reduces the occurrence of adverse events, so it is worthy of clinical promotion and application.
[Retracted] The Value of Nuclear Magnetic Resonance in Liver Nodular Lesions
Authors: Chen Si , Bao JiaLing
Published: August 2022

In order to analyze the value of contrast‐enhanced ultrasound (CEUS) combined with functional magnetic resonance imaging (fMRI) in the early differential diagnosis of liver nodular lesions, the authors studied the value of MRI in liver nodular lesions. A total of 82 patients with liver nodular lesions admitted to the hospital were selected for retrospective analysis; all of them underwent CEUS and fMRI examinations, and taking a biopsy or postoperative pathological examination results as the gold standard, the diagnostic value of CEUS, fMRI single item, and the two combined examinations for liver nodular lesions was analyzed by four‐table. The biopsy or postoperative pathological examination results showed that a total of 88 lesions were detected in 82 patients, including 51 patients with benign lesions, with 54 lesions, and 31 patients with malignant lesions, with 34 lesions. Taking biopsy or pathological examination results as the gold standard, the four‐table analysis CEUS had a sensitivity of 79.63%, a specificity of 82.35%, an accuracy of 80.68%, and a Kappa value of 0.603 for diagnosing benign and malignant liver nodular lesions. The sensitivity of fMRI in diagnosing benign and malignant liver nodular lesions was 83.33%, the specificity was 85.29%, the accuracy was 84.09%, and the Kappa value was 0.672; the combined sensitivity of the two in the diagnosis of benign and malignant liver nodular lesions was 94.44%, the specificity was 91.18%, the accuracy was 93.18%, and the Kappa value was 0.856, both of which were superior to single detection, and the difference in accuracy was statistically significant (χ2  = 5.683, P < 0.05). CEUS and fMRI have a certain value in the differential diagnosis of liver nodular lesions; the combination of the two can improve the diagnostic sensitivity and accuracy, and has more clinical application value.
Femtosecond Laser Combined with Double-Flange Polypropylene Suture Capsular Tension Ring Suspension for the Treatment of Subluxation of Lens in Marfan Syndrome
Authors: Zhou Li , Wu Shangcao , Guo Huafang
Published: August 2022

Purpose. To evaluate the use of femtosecond laser combined with double-flange polypropylene suture capsular tension ring (CTR) suspension to treat subluxation of lens in Marfan syndrome. The objective is to provide safer and more effective surgical procedures for patients. Setting. Eye Hospital, Aier Eye Hospital of Wuhan University, Wuhan, China Methods. In this retrospective study, we observed sixteen patients (16 eyes) with Marfan syndrome who had undergone this operation. Femtosecond laser incision was performed on the anterior capsule with the lens as the center. The suspending CTR was clipped to anterior capsule to support it, which was secured to the sclera with a double-flange polypropylene suture. Uncorrected visual acuity (UCVA), intraocular pressure (IOP), tilt, and decentration of the intraocular lens (IOL) and postoperative complications were evaluated. Results. All 16 patients were successfully implanted with suspended CTR and IOL after femtosecond laser assisted surgery. Visual acuity improved significantly after surgery (

p
<
0.01

). At 1 month, 3 months and 6 months postoperatively, the tilt of the IOL was

2.70
±
0.934
,
2.65
±
0.897
,
and
 
2.66
±
0.781

, and the decentration of the IOL was

0.30
±
0.770
,
0.30
±
0.682
,
and
 
0.29
±
0.737

; both had no statistically significant difference between the three groups. After the operation, 4 patients had hyphema and 2 patients experienced a temporary postoperative IOP increase. Only one flange was exposed one month after operation and recovered right after secondary adjustment. Conclusion. Femtosecond laser combined with double-flange polypropylene suture CTR suspension was effective in fixing the lens capsule to the scleral wall in cases of subluxation of lens seen in Marfan syndrome during our short-term observation. The long-term efficacy of this operation needs further observation and follow-up.
Evaluating DNA Methylation in Random Fine Needle Aspirates from the Breast to Inform Cancer Risk
Authors: Visvanathan Kala , Cimino-Mathews Ashley , Fackler Mary Jo , Karia Pritesh S. , VandenBussche Christopher J. , Orellana Mikiaila , May Betty , White Marissa J. , Habibi Mehran , Lange Julie , Euhus David , Stearns Vered , Fetting John , Camp Melissa , Jacobs Lisa , Sukumar Saraswati
Published: August 2022

Introduction. Critical regulatory genes are functionally silenced by DNA hypermethylation in breast cancer and premalignant lesions. The objective of this study was to examine whether DNA methylation assessed in random fine needle aspirates (rFNA) can be used to inform breast cancer risk. Methods. In 20 women with invasive breast cancer scheduled for surgery at Johns Hopkins Hospital, cumulative methylation status was assessed in a comprehensive manner. rFNA was performed on tumors, adjacent normal tissues, and all remaining quadrants. Pathology review was conducted on blocks from all excised tissue. The cumulative methylation index (CMI) for 12 genes was assessed by a highly sensitive QM-MSP assay in 280 aspirates and tissue from 11 incidental premalignant lesions. Mann–Whitney and Kruskal Wallis tests were used to compare median CMI by patient, location, and tumor characteristics. Results. The median age of participants was 49 years (interquartile range [IQR]: 44–58). DNA methylation was detectable at high levels in all tumor aspirates (median CMI = 252, IQR: 75–111). Methylation was zero or low in aspirates from adjacent tissue (median CMI = 11, IQR: 0–13), and other quadrants (median CMI = 2, IQR: 1–5). Nineteen incidental lesions were identified in 13 women (4 malignant and 15 premalignant). Median CMI levels were not significantly different in aspirates from quadrants (

p
=
0.43

) or adjacent tissue (

p
=
0.93

) in which 11 methylated incidental lesions were identified. Conclusions. The diagnostic accuracy of methylation based on rFNA alone to detect premalignant lesions or at-risk quadrants is poor and therefore should not be used to evaluate cancer risk. A more targeted approach needs to be evaluated.
The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
Authors: Phillips Caroline , Bhamra Inder , Eagle Catherine , Flanagan Eimear , Armer Richard , Jones Clifford D. , Bingham Matilda , Calcraft Peter , Edmenson Cook Alicia , Thompson Ben , Woodcock Simon A.
Published: August 2022

Wnt signaling is implicated in the etiology of gastrointestinal tract cancers. Targeting Wnt signaling is challenging due to on-target toxicity concerns and lack of druggable pathway components. We describe the discovery and characterization of RXC004, a potent and selective inhibitor of the membrane-bound o-acyl transferase Porcupine, essential for Wnt ligand secretion. Absorption, distribution, metabolism, and excretion and safety pharmacology studies were conducted with RXC004 in vitro, and pharmacokinetic exposure assessed in vivo. RXC004 effects on proliferation and tumor metabolism were explored in genetically defined colorectal and pancreatic cancer models in vitro and in vivo. RXC004 effects on immune evasion were assessed in B16F10 immune “cold” and CT26 immune “hot” murine syngeneic models, and in human cell cocultures. RXC004 showed a promising pharmacokinetic profile, inhibited Wnt ligand palmitoylation, secretion, and pathway activation, and demonstrated potent antiproliferative effects in Wnt ligand–dependent (RNF43-mutant or RSPO3-fusion) colorectal and pancreatic cell lines. Reduced tumor growth and increased cancer cell differentiation were observed in SNU-1411 (RSPO3-fusion), AsPC1 and HPAF-II (both RNF43-mutant) xenograft models, with a therapeutic window versus Wnt homeostatic functions. Additional effects of RXC004 on tumor cell metabolism were confirmed in vitro and in vivo by glucose uptake and 18fluorodeoxyglucose-PET, respectively. RXC004 stimulated host tumor immunity; reducing resident myeloid-derived suppressor cells within B16F10 tumors and synergizing with anti-programmed cell death protein-1 (PD-1) to increase CD8+/regulatory T cell ratios within CT26 tumors. Moreover, RXC004 reversed the immunosuppressive effects of HPAF-II cells cocultured with human peripheral blood mononuclear cells, confirming the multiple anticancer mechanisms of this compound, which has progressed into phase II clinical trials.

Significance:

Wnt pathway dysregulation drives many gastrointestinal cancers; however, there are no approved therapies that target the pathway. RXC004 has demonstrated the potential to block both tumor growth and tumor immune evasion in a genetically defined, clinically actionable subpopulation of Wnt ligand–dependent gastrointestinal cancers. The clinical utility of RXC004, and other Porcupine inhibitors, in such Wnt ligand–dependent cancers is currently being assessed in patient trials.
The Influence of Gadget Dependency on the Academic Procrastination Levels of Grade 12 STEM Students
Authors: Garcia Maria Isabel , Caraig Daisy Joy , Carator Kezia , Oyco Ma. Theresa , Tababa Gil Adrienne , Linaugo Joji , De Oca Phillip Raymund
Published: August 2022

Excessive phone use has already impacted academic achievement and perceived sociability of students, but the intensity of screen time has worsened with the transition to online learning. Consequently, students tend to delay their tasks as they are easily distracted. This research examines the influence of gadget dependency on the academic procrastination levels of students. It employs a descriptive correlational research design and gathered data from Grade 12 STEM students. Overall, the degree of gadget dependency among students is high, whereas academic procrastination level is moderate, and these two measures have a significant relationship. Analysis shows that students from ROC are significantly higher in both areas. However, sex and screen time do not impact the extent of gadget dependency and academic procrastination. Saliently, learning modality induces gadget dependency and academic procrastination levels. In conclusion, gadget dependency directly affects academic procrastination levels. Findings also suggest further research on other related effects of online and distance learning.
The Road to the EU’s Accession to the ECHR
Authors: Deftou Maria-Louiza
Published: August 2022

The dual European judicial protection of fundamental rights with the two Courts, namely the Court of Justice of the European Union (CJEU) and the European Court of Human Rights (ECtHR), represents a multi-layered, yet dialectic, model of protection with no formal hierarchy between its components. In the aftermath of Opinion 2/13 and faced with uncontrolled ‘unwanted migration’ flows, the EU judicature defended the principle of mutual trust at any cost and appeared to prioritise the protection of the Dublin regime (the EU responsibility allocation mechanism for examining asylum applications) instead of addressing the novel human rights challenges facing the Common European Asylum System (CEAS). Yet, their interplay has entered a new era since the renegotiation of the EU’s accession to the ECHR launched. By analysing the case law of the two Courts, this article thinks anew their relationship to ascertain whether the evolution of the accession project, throughout the latest decade, has affected the protection offered to ‘unwanted migrants’ in Europe.
The International Settlement of Disputes Under the (Draft) CAI
Authors: Ascensio Hervé
Published: August 2022

The EU-China Comprehensive Agreement on Investment (CAI) establishes a sophisticated inter-State dispute settlement mechanism, directly inspired by the World Trade Organization (WTO) and adapted to a bilateral context, as is also found in recent preferential trade agreements. The novelty here lies in its extension to the field of investment entry and investment facilitation. Some variations in detail are also important. Because of partial material overlap, it is necessary to consider how choice of forum is organized between CAI procedures and those under WTO or other agreements, and to clarify the possible interplay with bilateral investment treaties previously concluded by China with EU Member States. The attention given in CAI to specific procedures for sustainable development and subsidies is also notable. In sum, the solutions adopted show a willingness on the part of the two powers to exert a certain influence on developments in international investment law, without upsetting the methods of dispute resolution.
The Challenge of Critical Dialogue and the Study of Religions
Authors: Zene Cosimo
Published: August 2022

The correlation between dialogue and religion, both as conceptual apparatuses and as current practices, has had a long history. The purpose of this essay is to isolate one such instance – the “critical dialogue” taking place amongst scholars of religions – which involves also the dialogue scholars establish with their field of study and/or a given religious tradition. Following a brief clarification of terminology used, I will proceed to discuss concrete examples of critical dialogue within the Study of Religions and how this might be enhanced. Finally, I will draw some partial conclusions which might pave the way for this critical dialogue to improve and continue.
Taxonomy of Begonia canarana Miq.
Authors: AITAWADE MAKARAND MOHANRAO , SHARAD SURESH KAMBALE  , SHRIRANG RAMCHANDRA YADAV
Published: August 2022

Begonia canarana was collected and described from Mangalore, Canara, South Western India in 1851. Critical field observations, literature survey and herbarium consultations revealed that Begonia canarana is conspecific to the earlier described B. crenata, and it is synonymised here. Lectotypes for all names in synonymy with B. crenata are provided.
Magnetohydrodynamics Boundary Layer Flow Past a Wedge of Casson CuO-TiO2/EG Embedded in Non-Darcian Porous Media: Viscous Dissipation Effects
Authors: Indumathi N. , Ganga B. , Charles S. , Abdul Hakeem A. K.
Published: August 2022

The movement physiognomies and heat transmission of viscous dissipative Casson hybrid nanoliquid (cupric oxide CuO titania TiO2/ethylene glycol EG) and nanoliquid (titania TiO2/ethylene glycol EG) MHD flow via a wedge saturated with non-Darcy porous medium and
forced convection were the focus of this inquiry. The major partial differential equalities beside with the limit conditions were condensed to dimensionless forms by spending proper similarity transformation. The follow-on system of ODEs by the matching limit conditions was elucidated numerically
by way of MATLAB, bvp4c solver. The research ramifications for basic TiO2/EG and hybrid CuO–TiO2/EG nanoliquids were presented and explained in detail. The greater upsides of the Casson parameter, magnetic parameter, first and second order porous resistance parameters,
the velocity increases and the temperature profile decreases. Furthermore, the thermal field strengthens porosity and Eckert number. It was also found that the Nusselt number is an enhancing function of Casson parameter wheras, greater values of magnetic parameter and porosity parameter lessen
the Nusselt number.
Finite-time energy-to-peak control for Markov jump systems with pure time delays
Authors: Weng Falu , Zeng Yuqing , Yu Zhongan , Ding Yuanchun , Wang Huan
Published: August 2022

This study investigates finite-time energy-to-peak control for pure-time-delay Markov jump systems. The main objective is to obtain some theorems such that the corresponding pure-time-delay Markov jump systems are finite time energy-to-peak stable or stabilizable. First, based on mathematical transformation, the pure-time-delay Markov jump systems are described in a model description that includes the current system state and several distributed time-delay items. Second, according to linear matrix inequality (LMI) theory, a positive energy functional is constructed, which includes a triple integral item. Then, after some mathematical operations, some sufficient conditions are obtained for Markov jump systems to be finite-time energy-to-peak stable or stabilizable. The obtained results are expressed in LMIs, which can be conveniently solved by computers. Finally, examples are given to show the usefulness of the obtained theorems.
Soy, China’s Food Security, and the Brazilian Supply
Authors: Romano Schutte Giorgio , Campos Reinaldo
Published: August 2022

Soy production in Brazil has become a key part of food security policies and has contributed to China's development and social stability since the early 2000s. On the Chinese side, there is a sectoral policy that is part of a broader development strategy, while for Brazil there is a pragmatic response that aims to take advantage of an opportunity that has opened up. The relationship between the two countries, rather than being one of complementarity and reciprocal benefits, is one of asymmetrical interdependence.

A produção de soja no Brasil tornou-se parte fundamental das políticas de segurança alimentar e contribuiu para o desenvolvimento e a estabilidade social da China desde o início dos anos 2000. Do lado chinês, há uma política setorial que faz parte de uma estratégia de desenvolvimento mais ampla, enquanto para o Brasil há uma resposta pragmática que visa aproveitar uma oportunidade que se abriu. A relação entre os dois países, mais do que de complementaridade e benefícios recíprocos, é de interdependência assimétrica.
Does the journal impact factor predict individual article citation rate in otolaryngology journals?
Authors: Hussain Salman , Almansouri Abdullah , Allanqawi Lojaine , Philteos Justine , Wu Vincent , Chan Yvonne
Published: August 2022

Objective

Citation skew is a phenomenon that refers to the unequal citation distribution of articles in a journal. The objective of this study was to establish whether citation skew exists in Otolaryngology—Head and Neck Surgery (OHNS) journals and to elucidate whether journal impact factor (JIF) was an accurate indicator of citation rate of individual articles.

Methods

Journals in the field of OHNS were identified using Journal Citation Reports. After extraction of the number of citations in 2020 for all primary research articles and review articles published in 2018 and 2019, a detailed citation analysis was performed to determine citation distribution. The main outcome of this study was to establish whether citation skew exists within OHNS literature and whether JIF was an accurate prediction of individual article citation rate.

Results

Thirty-one OHNS journals were identified. Citation skew was prevalent across OHNS literature with 65% of publications achieving citation rates below the JIF. Furthermore, 48% of publications gathered either zero or one citation. The mean and median citations for review articles, 3.66 and 2, respectively, were higher than the mean and median number of citations for primary research articles, 1 and 2.35, respectively ( P < .001). A statistically significant correlation was found between citation rate and JIF ( r = 0.394, P = 0.028).

Conclusions

The current results demonstrate a citation skew among OHNS journals, which is in keeping with findings from other surgical subspecialties. The majority of publications did not achieve citation rates equal to the JIF. Thus, the JIF should not be used to measure the quality of individual articles. Otolaryngologists should assess the quality of research through the use of other metrics, such as the evaluation of sound scientific methodology, and the relevance of the articles.
IT/QA and Regulatory Aspects of Digital Pathology: Results of the 8th ESTP International Workshop
Authors: Boisclair Julie , Bawa Bhupinder , Barale-Thomas Erio , Bertrand Lise , Carter Jonathan , Crossland Richard , Dorn Celine , Forest Thomas , Grote Sabine , Gilis Anja , Hildebrand Deon , Knight Brian , Laurent Sébastien , Marxfeld Heike Antje , Østergaard Steen Jørgen , Roguet Thibault , Schlueter Thorsten , Schumacher Vanessa , Spehar Richard , Varady William , Zeugin Christian
Published: August 2022

Digital toxicologic histopathology has been broadly adopted in preclinical compound development for informal consultation and peer review. There is now increased interest in implementing the technology for good laboratory practice–regulated study evaluations. However, the implementation is not straightforward because systems and work processes require qualification and validation, with consideration also given to security. As a result of the high-throughput, high-volume nature of safety evaluations, computer performance, ergonomics, efficiency, and integration with laboratory information management systems are further key considerations. The European Society of Toxicologic Pathology organized an international expert workshop with participation by toxicologic pathologists, quality assurance/regulatory experts, and information technology experts to discuss qualification and validation of digital histopathology systems in a good laboratory practice environment, and to share the resulting conclusions broadly in the toxicologic pathology community.
Consumer and Provider Perspectives on Technologies Used Within Aged Care: An Australian Qualitative Needs Assessment Survey
Authors: Moyle Wendy , Pu Lihui , Murfield Jenny , Sung Billy , Sriram Deepa , Liddle Jacki , Estai Mohamed , Lion Katarzyna ,   The AACT Collaborative
Published: August 2022

We undertook a qualitative assessment of aged care technology needs from the perspective of consumers and providers using a cross-sectional survey that assumed a largely open-response format. We recruited a convenience sample of individuals aged 18 years or older, lived in Australia, and self-identified as either an older adult ( n = 133), an informal caregiver of an older adult ( n = 27), and/or clinician, healthcare practitioner, and aged care provider ( n = 148). Survey responses were analyzed using a descriptive qualitative content analysis approach to interpret meaning from written survey responses. We identified seven themes reporting that technologies used in aged care do not appear to be meeting end-user needs. Supporting the Technology Acceptance Model, consumers and providers perceive usefulness of the technology and its actual ease of use as drivers of acceptance toward gerontechnology. Ten recommendations are proposed to support technology use and the quality of aged care.
Omni-synergy and the Singularity: Looking Both Ways at the Intersection of Science and Theology
Authors: Williams Jay Lennon George
Published: August 2022

This article will exemplify John David Trentham's Inverse Consistency Protocol (ICP) in analyzing Ray Kurzweil's seminal work: "The Singularity is Near: When Humans Transcend Biology." If Kurzweil’s vision of transhumanism becomes viable, Christian educators will face unprecedented implications and challenges. This article will serve as a primer into Kurzweil’s vision and seek to initiate scholarly conversation toward a much-needed Christian worldview response—a response that would be greatly benefited from wisdom gained by foresight, not hindsight.
Safeguarding in Church: Children and Young People’s Perceptions of Safety in Religious and Other Faith-Based Settings
Authors: Russell Douglas H. , Stewart Jacqueline , Higgins Daryl J.
Published: August 2022

Organizations that interact with children and young people have a duty of care to ensure the safety of those children and young people from any manner of abuse, particularly from child sexual abuse. Faith-based (“religious”) organizations are of particular interest due to the number of victims/survivors speaking out about their experiences of grooming, child sexual abuse, and other forms of harm in religious organizations. Focusing on addressing the risks and improving safeguarding efforts, prevention activities benefit from giving children agency and a voice. We conducted a study using two focus groups with children and young people involved with two different Christian denominations. We conducted activities and led discussions regarding their views about safety in the context of the faith-based organization with which they engage. Children and young people described different potentially unsafe situations, their likely frequency, and the level of impact such situations would have from their own point of view. They also described how they thought adults in their faith-based organization would see them. Thematic analysis of the data supported four themes related to young people’s sense of safety: concerning behavior of adults and other young people, fear of judgment by others (adults and peers), sense of or lack of empowerment due to power dynamics, and the importance of a sense of “familiarity.” Visual comparisons of the data on scatterplots suggested differences not only in the level of impact and frequency of potentially unsafe situations between young people and adults but also between the two denominations. Children and young people can provide a wealth of information regarding their safety concerns when involved in programs and services at faith-based organizations. Clergy and other faith-based organizational leaders should consider how the context in which young people are involved (including interdenominational and interfaith difference, as well as the diverse types of activities young people are involved with) can affect their safety concerns.
Towards greater integration of building information modeling in the architectural design curriculum: A longitudinal case study
Authors: Laovisutthichai Vikrom , Srihiran Kaweekrai , Lu Weisheng
Published: August 2022

Building information modeling (BIM) has been a disruptive development in the global architecture, engineering, construction and operations (AECO) industry. While architecture schools have sought to integrate BIM into their curricula, most current pedagogical approaches and lessons are derived from engineering and construction management perspectives. There is a scarcity of investigations to monitor outcomes, reveal difficulties and articulate strategies for this context. This research explores how to better incorporate BIM into the architectural design curriculum. It does so by gathering pedagogical strategies, redesigning the curriculum and taking action in one of Thailand’s top architecture schools. The study reveals that treating BIM as a discrete topic in the architectural curriculum – where BIM is not so much the main focus, is misunderstood and is alleged to jeopardize creativity – is ineffective. Instead, infusing BIM learning modules throughout the existing curriculum structure, core design studio and supporting areas allows for the consistent and concurrent development of BIM skills and architectural knowledge. The concepts and practice examples developed in this research, along with feedback received and challenges met, constitute a valuable resource for further BIM-integrated architecture curriculum development. Future studies are recommended to improve BIM learning and advance the full potential of BIM in the education of next-generation architects.
Response surface methodology based parametric study for AISI H13 die steel using customized designed 3D printed Ti64 multi-nozzle polishing tool
Authors: Choudhary Shubham , Duvedi Ravinder Kumar , Saini Jaswinder Singh
Published: August 2022

The work presents a study on FJP polishing of AISI H13 die steel using 3D printed multi nozzle (dual orifice) polishing tool and Silicon Carbide (SiC) abrasive slurry. It presents a simultaneous effect of feed rate and spindle rotation on the percentage change in surface roughness (%[Formula: see text]). Central Composite Design (CCD) method was used to design the experimentation plan and Analysis of Variance (ANOVA) was performed to evaluate the optimum values of the process parameters. The regression model developed for the FJP process was validated by polishing the AISI H13 workpiece with 39[Formula: see text] average initial surface roughness with the optimized process parameters; feed rate of [Formula: see text] and spindle rotation of [Formula: see text]. The optimized FJP parameters were able to generate the surface roughness of [Formula: see text]. The results obtained from the confirmatory experiments were found to be very close to the predicted results which validated the developed regression model. To further enhance the polishing efficiency, the optimum process parameters were used to polish AISI H13 die steel workpiece, the surface roughness was reduced from 390 to 110 nm in 15 min with 12 number of passes which shows the reduction in peaks and valleys with surface improvement of 71.79%.
Sources of variability in metro train-induced vibration
Authors: Qu Xiangyu , Thompson David , Ma Meng , Li Minghang , Ntotsios Evangelos
Published: August 2022

In previous in-situ measurements of metro trains it has been found that the velocity level on the track or tunnel wall may vary significantly between different train passages, even though the measuring section, the type of trains and the track and tunnel conditions are identical. An investigation is carried out into the sources of this variability, using a 3D train-track numerical model. This is built using the software SIMPACK and ABAQUS, and is connected through one-way coupling to a finite element model of the tunnel and soil. These models are used to study the influence of various train parameters, including the wheel and rail unevenness, train speed and degree of train loading. For comparison, in-situ measurements were made of the dynamic response of the rail and tunnel wall. The rail roughness at the site as well as the wheel unevenness of all 48 wheels for one train were measured. The results from the model indicate that the wheel unevenness affects the rail velocity level in the frequency region between 25 and 250 Hz and tunnel wall vibration above 5 Hz. The rail velocity level can vary by up to 20 dB due to wheel unevenness, with the largest variations occurring in the frequency bands 50–63 Hz. Variations in passenger loading affect the train-induced vibration by up to 4.5 dB, mainly in the low frequency region. When the train speed varies within a range of ±20% relative to the nominal speed 60 km/h, the frequencies of the peaks are shifted and the level in some frequency bands can change by as much as 10 dB. However, the largest influence is that of the wheel unevenness. It is concluded that the variation in these parameters, especially the wheel and rail unevenness, should be considered to achieve reliable predictions of train-induced vibration.
Environmental sustainability risk, institutional effectiveness and urbanization
Authors: Abaidoo Rexford , Agyapong Elvis Kwame
Published: August 2022

This study examines the effect of urbanization, institutional quality and other variables on environmental sustainability risk among economies in Sub-Saharan Africa (SSA). Environmental sustainability risk is examined from three main perspectives – emission of gases inimical to the environment (CO2 emissions), exploitation of land and water resources (ecological footprint) and exploitation of resources devoid of the requisite savings and education expenditure (genuine sustainability risk). Empirical analyses were performed using the Limited Information Maximum Likelihood (LIML) Instrumental Variable estimation technique. Estimated results suggest that urbanization, population growth and increase commodity prices on the global market (for key export commodities) worsen CO2 emissions among economies in the sub-region. The results further suggest that urbanization, population growth, governance and institutional structures increase resource exploitation. Additional results suggest that institutional quality lessens adverse effect urbanization has on environmental sustainability risk (CO2 emissions) and genuine sustainability risk; but exacerbates the impact urbanization has on ecological footprint. Given these findings, this study recommends conscious efforts at improving governance and institutional structures among governments in the sub-region to lessen adverse effect of urbanization and population growth on environmental sustainability risk.
Acute renal injury from thrombotic microangiopathy associated with enteritis in New Zealand white rabbits
Authors: Waggie Kimberly S. , Snyder Jessica M. , Treuting Piper M.
Published: August 2022

Over a 3-y period, 12 adult New Zealand white (NZW) rabbits were presented for postmortem examination following variably long periods of inappetence and soft-to-liquid stool production. Postmortem findings included serosanguineous fluid in abdominal and thoracic cavities, dark-red-to-white renal foci, reddened intestinal serosa, and pulmonary edema. Microscopically, mesangial changes and thrombi were observed in renal glomeruli, and mild-to-severe enteritis was observed. These findings resemble hemolytic uremic syndrome, which typically follows enterocolitis associated with Shiga toxin (Stx)-producing Escherichia coli infection. In our case series, various gram-negative bacteria, most commonly E. coli, were isolated from the intestinal tracts; however, Stx production was not demonstrated. Evidence of Encephalitozoon cuniculi infection, a common cause of renal disease in rabbits, was also not found. Our cases suggest that gram-negative enteric bacteria should be included in the differential diagnosis of renal disease in NZW rabbits, especially in cases with an accompanying clinical history of gastrointestinal disorder.
Diagnostic Evaluation of Depression Screening Tools in Asian New Zealanders
Authors: Montayre Jed , Liu Megan F. , Wang Tongyao , Zhao Ivy Yan , Dimalapang Eliazar , Chang Hui-Chen (Rita) , Ho Mu-Hsing
Published: August 2022

This study aimed to compare the Kessler Psychological Distress Scale (K10) and Short-Form 12-Item Health Survey Mental Component Score (SF-12 MCS) for the effectiveness as screening tools for depression in Asian New Zealanders. A national, representative New Zealand Health Survey (NZHS) data set was used. In total, 1,277 participants were included in the analyses. The sensitivity and specificity values, as well as the areas under the receiver operating characteristics curves (AUROC), for the K10 and the SF-12 MCS scores were examined. The AUROCs for K10 and SF-12 MCS were 0.787 (95% CI [0.736, 0.837]) and 0.725 (95% CI [0.656, 0.793]), respectively. A less than optimal sensitivity and positive predictive value of K10 support the need to reexamine the optimal cut-off point according to the results of the Youden index. Strengthening the K10 predictive accuracy will increase the practical application among Asian populations.
Affective diaries of quarantine: Writing as mourning
Authors: Mandalaki Emmanouela
Published: August 2022

Challenging the bodily-detached logos qualifying as perfect knowledge in academia, I write here to mourn, driven by a visceral need to speak of vulnerabilities and affects, which continuously become overexposed under the COVID-19 pandemic and the corresponding lockdown periods. My diary notes reflect my affective ambivalences, ambiguities, and contradictions during this time, which I interweave with critical feminist theories on affect and mourning as an emancipating process. In so doing, I propose academic writing as a mourning process with heightened relational, ethical, and esthetic possibilities. Mourning the collateral losses and multi-dimensional vulnerabilities experienced during this pandemic provides, I suggest, a relational language to speak of embodied affects to challenge and resist normative structures oppressing difference and otherness, including the affectively disengaged academic logos. I propose that experiencing academic writing as a mourning process enables us to develop the embodied subjectivities necessary to survive the crises surrounding our lives, which the pandemic has left bare. Doing so motivates a kind optimism necessary for driving desired change, collectively, in academia and in broader society.
“The dinosaurs are so loud; they can’t sleep. Zzzz”: Supporting emergent bilingual children’s reading comprehension through digital literacies
Authors: Brown Sally , Hao Ling , Zhang Rong
Published: August 2022

As classrooms worldwide become diverse, the ways teachers engage children in literacy learning must be inclusive to accommodate the multitude of languages spoken. Multimodal literacy practices using digital tools provide innovative opportunities for emergent bilinguals to express their meaning-making processes. This paper details a year-long investigation into the multimodal literacy practices of eight young children who spoke different languages within an English-only classroom setting. The children showcased their reading comprehension through digital ensembles produced in responses to picturebooks. Transcribed small group interactions were analyzed to capture how one mode influenced another, and content analysis was applied to the student work samples. The findings reveal specific ways the emergent bilinguals transformed available resources to make sense of texts.
Development and application of an algorithmic-parametric tool to assess the contribution of urban forestry to mitigate floods
Authors: Martins Iago Longue , Lyra Ana Paula
Published: August 2022

As an impact of climate change, water-related disasters, such as floods, are becoming more frequent. In this context, there is an increasing demand to improve the resiliency of urban settlements, using multiple approaches and techniques. This paper assesses one of those techniques, by developing an algorithmic-parametric tool to quantify how urban forestry reduces flood impacts from rainfall runoff. The assessment was comprised by three main methodological steps: (#1) observing the scientific literature on “the sponge effect” observed in green infrastructures; (#2) developing an algorithmic-parametric tool using the Grasshopper application to estimate rainfall runoff, considering the influence of urban forestry design factors; and (#3) performing digital simulations with this parametric tool using a Rhinoceros-Grasshopper interface. Results indicate this method is effective in assessing the efficacy of green interventions to mitigate urban flood damage and also in foreseeing how different design strategies impact urban hydrological dynamics.