bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Impacts of Changes in the Currency Exchange Rate on Air Pollution in Tehran: A Sectoral Review
Authors: Goharipour Hamed , Firoozabadi Seyyed Soroosh
Published: May 2022

The 2022 winter was the most polluted season of Tehran in the past five years. Tehran is rated as one of the world’s most polluted cities in World Air Quality Index (AQI) Ranking. Air pollution in Iran’s big cities is the consequence of several economic, technological, management, and socio-cultural factors. But how important is the currency exchange rate? Since the Iranian revolution in 1979, the country has been subjected to sanctions imposed by a varied of international entities, namely the United States. The economic and political consequences of the exchange rate have so far been the central topics of interest to researchers, journalists, and officials. Although multiple factors affect the level of air pollution in cities, this study narrows down its focus on the 2018-2020 period, during which changing in Dollar to Rial have burdened environmental strategies in Iran. National and public entities do not officially reveal the trade volume between Iran and the international community, importing and exporting transactions, and foreign and domestic investments. Therefore, this descriptive-analytical paper examines the experts’ and official debate over the topic in the major national and international newspapers, news agencies, and interviews. Findings reveal political debate and economic consequences, namely a decrease in the Iranian Rial exchange rate against the U.S. dollar, have had undeniable impacts on the national and local actions related to five key areas of public transit, motorcycles, automobiles, petrol, and refineries and power plants, which are five significant pollution factors in Tehran.
Factors Affecting Loan Loss Provisions during the Covid-19 Pandemic – The Case of Commercial Banks in Vietnam
Authors: Nguyen Dung Thi Thuy
Published: May 2022

Credit is considered a crucial activity of commercial banks; it accounts for the most significant proportion of the bank's total assets and is also an activity that carries great risks. The study uses OLS, FEM, REM, and FGLS to assess the factors affecting loan loss provisions (LLPs) of 20 Vietnamese commercial banks during the Covid-19 pandemic from Q1/2020 to Q4/2021. The result of the model is based on FGLS to overcome the phenomenon of heteroscedasticity after using estimation by OLS, FEM, REM, showing that the factors affecting LLP of Vietnamese commercial banks during the Covid pandemic include: bank size (SIZE), non-performing loans ratio (NPL), a ratio of pre-tax profit and provision to total assets (CROA), loans to total assets ratio (LOAN), and credit growth (ΔCREDIT). Research results using the FGLS method show that bank size, bad debt ratio, pre-tax profit ratio and provision to total assets and credit growth positively impact the LLP of the Vietnamese commercial banks in the Covid pandemic. However, interestingly, the percentage of loans to total assets can decrease the provision for loan losses. Thereby, the study proposes some policy implications as follows: The SBV needs to have the policy to limit credit growth and bad debt ratio for commercial banks to control the competition for a market share of loans without ensuring the quality of loans, leading to an increase in credit risk and LLP. Furthermore, each Vietnamese commercial bank needs to develop and apply a practical and comprehensive credit process to ensure debt recovery to avoid a lot of bad debts. For new customers, banks need to fully assess all aspects to predict the level of risk before deciding to provide loans. Additionally, the long-term effects of Covid-19 cause difficulties for commercial banks' activities, SBV needs to consider supportive policies through interest rate reduction, grace period, and debt extension to increase financial performance and maintain market share and profits of commercial banks.
Autoregressive Integrated Moving Average (ARIMA) and Long Short-Term Memory (LSTM) Network Models for Forecasting Energy Consumptions
Authors: Shariff Samir M.
Published: May 2022

Unlike other sources of energy, electricity can't be stored. Therefore, an estimation of Energy Consumption (EC) with good accuracy is required to manage demand and supply in the smart grid. Not only good accuracy, but reliability is also on-demand in the prediction model to optimize resource allocation. Therefore, in this study we have implemented and examine two different models: a machine learning model, Autoregressive Integrated Moving Average (ARIMA), and a deep learning-based model Long Short-Term Memory (LSTM). Although ARIMA showed powerful statistical analysis and less robustness, LSTM demonstrated highly accurate results which may stop us to lead false alarming of over-demand and low consumption of energy. In last, we have concluded our result by presenting significant improvement in forecasting energy by LSTM using various evaluation criteria e.g., Mean Square Error (MSE), Root Mean Square Error (RMSE), and other normalized matrices.
Tamoxifen: The Past, Present, and Future of a Previous Orphan Drug
Authors: Matariek Ghadier , Teibo John Oluwafemi , Elsamman Kholoud , Teibo Titilade Kehinde Ayandeyi , Olatunji David Idowu , Matareek Amira , Omotoso Olabode Ebenezer , Nasr Ahmed
Published: May 2022

Tamoxifen, a non-steroidal selective estrogen receptor modulator is a widely used drug for the prevention and breast cancer treatment. It binds to the hormone-receptors to prevent the binding of the cancer cells in the breast to the hormones they need for growth. It undergoes metabolic activation which converts it to an active metabolite (endoxifen and afimoxifene) by the action of cytochromeP450 isoforms CYP2C9, CYP2D6, CYP3A4.

Notable among its side effects include hot flashes, weight loss, endometrial and uterine cancer, irregular periods, stroke, abnormal fetal development in pregnant women and others discussed in our review. Other than breast cancer, medicinal potential of tamoxifen has been probed in several therapeutic targets. The outcome has shown great promise in managing osteoporosis, infertility, advanced gliomas, lung and liver cancer, among many others. The major drawbacks on the use of tamoxifen have been centered on its resistance and associated side effects. Some of the notable future direction of tamoxifen is centered on overcoming its resistance as well as repurposing of tamoxifen in wider cancer settings. 

Targeting LEM4 as a biomarker for predicting tamoxifen resistance in ER-positive breast cancer could be a viable research area in the future to overcome tamoxifen resistance.
Management of Incarcerated Inguinal Hernia in Children at the University Hospital of Antananarivo - Joseph Ravoahangy Andrianavalona
Authors: Raherison Aristide R. , Andriamanarivo Lala R. C. , Andriantsoa Arifenitra A. A. , Hunald Francis A. , Andriamanarivo Mamy L.
Published: May 2022

Inguinal hernia is one of the most common surgical pathologies in children. The main risk is the evolution towards strangulation especially before the age of one year. Our study reports our experience on the management of strangulated hernias in children at the University Hospital Center of Antananarivo - Joseph Ravoahangy Andrianavalona (CHUA - JRA).

This is a 12-month retrospective study. The parameters studied are the age of onset of strangulation, gender, the side concerned, clinical manifestations, therapeutic methods, outcomes.

Of 74 cases collected, 96% were male. The right side predominated with 71.62% of cases. More than 70% of the cases were less than a year old, of which 50% were less than 3 months old. Besides the signs of strangulation, 10 cases presented an evident occlusive syndrome and 5 cases had come with a deterioration of the general state. Among 56 cases of initial reduction, 49 cases were reduced and their surgical treatment was postponed from 2 to 7 days. Cases with evident signs of complications, reduction failure, and cases of ovarian hernias had emergency surgery. Two cases of immediate post-operative death, 6 cases of testicular necrosis and two cases of recurrence over a three-month follow-up were deplored in patients operated on immediately.

In case of strangulated hernia, delayed surgery after an immediate reduction offers a better prognosis. The main factor limiting this method is the late consultation responsible for advanced visceral complications.
Izoformy mikroRNK miR-148a i miR-203a predpolozhitel'no igrayut rol' supressorov kolorektal'nogo raka
Authors: Нерсисян С. А.
Published: May 2022

Izoformy mikroRNK — klass korotkih nekodiruyushchih RNK, osushchestvlyayushchih regulyaciyu ekspressii genov. Izoformy mikroRNK otlichayutsya ot kanonicheskih mikroRNK neskol'kimi nukleotidami na koncah molekuly, prichem variacii s 5′-koncov mikroRNK izmenyayut mnozhestvo genov-mishenej. Cel'yu raboty bylo provesti analiz funkcional'noj aktivnosti 5′-izoform mikroRNK v tkanyah kolorektal'nogo raka. Misheni 5′-izoform mikroRNK byli predskazany s pomoshch'yu bioinformaticheskih programm miRDB i TargetScan. Poluchennye dannye o mishenyah 5′-izoform mikroRNK byli integrirovany s dannymi sekvenirovaniya mRNK i izoform mikroRNK obrazcov pervichnyh kolorektal'nyh opuholej proekta The Cancer Genome Atlas Colon Adenocarcinoma. Dlya postroeniya seti vzaimodejstvij izoform mikroRNK, ih mishenej i transkripcionnyh faktorov po integrirovannym dannym ispol'zovali algoritm miRGTF-net. Pokazano, chto vysokoekspressirovannye pri kolorektal'nom rake izoformy mikroRNK, razlichayushchiesya odnim nukleotidom na 5′-konce molekuly, imeyut ne bolee 30% obshchih mishenej. V regulyatornoj seti vzaimodejstvij vyyavleny naibolee aktivnye izoformy mikroRNK. Urovni ekspressij kanonicheskoj mikroRNK hsa-miR-148a-3p i ee predskazannyh mishenej, yavlyayushchihsya regulyatorami kletochnoj proliferacii (CSF1, ETS1, FLT1, ITGA5, MEIS1, MITF, RUNX2), byli znachimo otricatel'no korrelirovany, otkuda mozhet sledovat' protivoopuholevaya rol' dannoj molekuly. Kanonicheskaya mikroRNK hsa-miR-203a-3p|0 i ee 5′-izoforma byli antikorrelirovany s razlichnymi genami-mishenyami, no pri etom obe potencial'no podavlyali ekspressiyu genov, vovlechennyh v epitelial'no-mezenhimnyj perekhod: SNAI2 i TNC.
An Analysis of The Intriguing Murder Mystery in Stephen King’s The Outsider
Authors: Manju Dr. A.J , P M Anas
Published: May 2022

There is no such thing as a perfect crime. In every case, sooner or later the culprit will be found and he or she shall face the law. Even in a case that can be seen as a perfect crime there will be some piece of information left by the criminal. The solving of the case depends upon the ability of the investigator to find out that hint and put it into investigation. But what happens when the crime is not done by an ordinary human and the police officials have arrested an innocent man? Stephen King’s The Outsider is all about such an inhuman being who has done several crimes especially the Raping and Murdering of innocent children. We can’t even think about a situation when we are blamed or even arrested for another man’s crime. But what happens when one experiences a scenario where the innocent is also guilty? This contradiction is portrayed in The Outsider as it follows the story of a detective whose search for the absolute truth leads him to discover evil in its pure form.

Detective Ralph Anderson is all set for arresting Terry Maitland who is an esteemed sports trainer and high school educator for the killing and confrontation of an eleven year old boy, Frank Peterson. All the clues are against Terry Maitland. Ralph Anderson commands to arrest him at a local baseball game in front of his household and the whole horde. But Maitland had a mighty justification, he was in the company of some educators hundreds of miles away and there is video authentication to confirm it. His fingerprints are also there on a book where he claimed to be. How can he be at two places at the same time? However the Intriguing murder mystery is solved at last by the brave efforts of Ralph Anderson and his teammates.
Manifestation of Pessimism in Toni Morrison’s Select Works: Beloved, The Bluest Eye and Jazz
Authors: Thakur Sajal , Sarkhel Dr. Ranjana Das
Published: May 2022

Toni Morrison’s works are elevated voice of Afro-American culture. As Afro-American has been bearing the burden of past history, slavery, race, gender and identity crisis issues in society, Toni Morrison herself forced to speak about them in their works. She herself is the part of historic past events like racism and identity crisis issues and that’s why her mind is more into the pain which they suffered. Toni Morrison is more focused on pessimism to show the reality and harsh truth of society, which reflected through her characters.  No doubt Toni Morrison was loud to raise the problematic issues strongly but her appeal to wove her characters is tend to their circumstances, how they tortured and suffered through their whole life and it continues generation to generation. The clear aim of Morrison is to make aware today’s generation about Afro-American society its history about the injustice. So that they can be aware of their rights and able to fight for own.
The Theory of Government in Arabic Grammatical Traditions: Chomskyan Generative Grammar Perspective
Authors: Salim Muhammed , Al Deen Bedoor Sharaf , Masoud Mohammed
Published: May 2022

Early Arab grammarians used scientific tools to analyze the sentence structure. Their scholarship is best manifested in the establishment of the Governor theory. It assumed that governors change the parsing signs of the word. Two major types of governors were identified:  the expressed and the abstract governors. Governor theory dominated the linguistic thinking not only at that time but it is still at the core of Arabic linguistic discussions nowadays. The purpose of this study is twofold: (a) to give a brief introduction about the theory of governor in Arabic, and (b) to compare the governor theory in Arabic with the theory of government presented in Chomsky’s (1988) Government and Binding theory. The study revealed that Sibawayh (793) laid the foundations of the Governor theory and it matured in the works of the Basrans and the Kufans. The study also showed some agreement between Chomsky’s theory of government and Arabic Governor Theory. Nevertheless, there is a difference in the nature and the types of governors between the two theories.
Penyesuaian Diri Siswa Sekolah Berasrama (Studi Deskriptif Komparatif Terhadap Siswa SMAN 1 Sumatera Barat)
Authors: Randi Peni Okto
Published: May 2022

Self adjustment of students in a boarding school environment is the ability to live and fair, so that he was satisfied with themself and to the environment. Many factors affect the students in the school adjustment as gender, cultural backgrounds and grade levels (maturity). This study purpose to describe the adjustment of students in terms of gender, cultural background, and grade levels. The research was ex post facto by using factorial design 2 x 2 x 3. The population is students of SMAN 1 West Sumatra. The total sample were 168 people selected by stratified random sampling technique and combined with the proportional sampling technique. The instrument was a questionnaire. Data were analyzed by analysis of variance (ANOVA). The result showed: (1) the level of adjustment of students in general were in the high category, (2) the level of adjustment male and female were in at the high category, and there was difference of adjustment of students based on the gender, mean score of female students higher than male students, (3) the level of adjustment of students in terms of cultural background (Minang and non-Minang) were in high category, and there are differences in the adjustment of students based on the background of the culture, (4) the level of adjustment student review grade levels (X, XI, and XII) were in high category, and there is no difference adjustment students based on grade level, and (5) the level of adjustment of students in terms of gender, cultural background, and grade levels were in category high, and there is no interaction between these variables in explained the adjustment of students.
Analisis Self Esteem Dengan Perilaku Verbal Abuse Pada Guru
Authors: Saragih Nurul Azmi
Published: May 2022

This study aims to determine the analysis of the relationship between self-esteem and verbal abuse in teachers. The data collection instrument used to measure self-esteem and verbal abuse was a Likert scale. Self-esteem is measured based on aspects of self-esteem, namely strength, courage and virtue, on verbal abuse it is measured based on forms of verbal abuse, namely saying harsh words, slandering, threatening, scaring, insulting, exaggerating the mistakes of others. . The study population and the sample of this study were 33 respondents. The data analysis used is Simple Linear Regression Analysis. The results showed that there was a negative relationship between self-esteem and verbal abuse at the coefficient R = -0.467 and p = 0.003 means (p <0.05). This means that there is a negative relationship between self-esteem and verbal abuse behavior in teachers, so that the lower the self-esteem, the higher the verbal abuse.
Establishing partnerships for rural development
Authors:   Babeș-Bolyai University, Faculty of Geography, Cluj-Napoca, Romania, Nagy Júlia Angéla , Filip Valentin ,   Babeș-Bolyai University, Faculty of Economics and Business Administration, Cluj-Napoca, Romania
Published: May 2022

Over the last three decades partnership development among various groups has been increasingly encouraged as means to stimulate development in rural areas. Nevertheless, despite the support given to partnerships between organizations, critics question their effectiveness and the economic endeavours to stimulate local development are contested. Consequently, our study seeks to investigate what are the economic and organizational conditions that influence consideration when joining a local partnership but also the main constraints and individual motivation to develop cooperative behaviour. The analysis shows that while there is openness in creating or developing joint ventures, the availability of financial resources, lack of strategic planning, lack of communication and trust are factors that can have significant influence on the effectiveness of the partnership and consequently on its contribution to the local development.
Sobre David Carbajal López (coord.), Proyectos episcopales y secularización en México, siglo XIX
Authors: Bárcenas García Felipe
Published: May 2022

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Sobre Agustín Sánchez Andrés, Entre la espada y la pared. El fracaso del primer experimento autonómico español en Cuba, 1897-1898
Authors: Rojas Rafael
Published: May 2022

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Sobre Javier Fernández Sebastián, Historia conceptual en el Atlántico ibérico. Lenguajes, tiempos, revoluciones
Authors: Portillo Valdés José María
Published: May 2022

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Sobre Paula Bruno, Martín García Mérou. Vida intelectual y diplomática en las Américas
Authors: Carrillo Reveles Veremundo
Published: May 2022

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Sobre José Manuel Velasco Toro y Lucía Santos García, Cosamaloapan. Una historia agraria regional de la gran propiedad al ejido
Authors: Xala Paxtián David Misael
Published: May 2022

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Sobre Horacio Tarcus, Las revistas culturales latinoamericanas: giro material, tramas intelectuales y redes revisteriles
Authors: Marichal Carlos
Published: May 2022

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ÖZEL GEREKSİNİMLİ ÖĞRENCİSİ OLAN SINIF ÖĞRETMENLERİNİN BİREYSELLEŞTİRİLMİŞ EĞİTİM PROGRAMI (BEP) HAZIRLAMADAKİ YETERLİKLERİ
Authors: ŞAHBAZ Ümit , GÜDER Orhan
Published: May 2022

Her insan birbirinden farklı özelliklere sahiptir ve insanların kendini gerçekleştirmesi için bu farklılıklarının dikkate alınması gerekmektedir. Bu sebeple toplumda farklılık gösteren bireylerin toplumsal haklarının korunması önemlidir. Bu haklardan bir tanesi de eğitim hakkıdır. Dolayısıyla zihinsel ve bedensel olarak akranlarından ayrılan bireylere özel eğitimi verilmesi gerekmektedir. Bu sebeple okullarda bireyselleştirilmiş eğitim programı (BEP) birimi oluşturulmaktadır. Bu birimde yer alan sınıf öğretmenin BEP konusundaki yeterliklerin bilinmesi önemlidir. Sınıf öğretmenlerinin BEP yeterliklerinin betimsel tarama modeli ile belirlendiği araştırmaya, 2020-2021 eğitim-öğretim yılında Kütahya ili genelinde görev yapan 155 sınıf öğretmeni katılmıştır. Veriler demografik bilgiler formu ve “Öğretmenler için Bireyselleştirilmiş Eğitim Programı Yeterlik Ölçeği” ile toplanmıştır. Araştırma bulgularına göre, sınıf öğretmenlerinin BEP konusunda gerekli yeterlikte olduğu, kıdemli öğretmenlerin, lisansüstü eğitime sahip öğretmenlerin, meslek öncesi özel eğitim dersi alan öğretmenlerin BEP yeterlik düzeylerinin yüksek olduğu sonucuna ulaşılmıştır.
UZAKTAN EĞİTİM SÜRECİNDE ORTAOKUL 5. SINIF İNGİLİZCE DERSİNDEKİ MEVCUT DURUMUN İNCELENMESİ
Authors: DEMİR Ramazan , KARAKUS Memet
Published: May 2022

: Bu araştırmanın amacı uzaktan eğitim sürecinde ortaokul 5. Sınıf İngilizce dersindeki mevcut durumun incelenmesidir. Karma araştırma modelinin kullanıldığı araştırmada çalışma grubunu devlet okullarında okuyan 5. Sınıf öğrencileri ve İngilizce öğretmenleri oluşturmaktadır. Nicel verilerin toplanmasında İngilizce başarı testi, uzaktan eğitim sürecinde kullanılan ders takip formları ve e-okul kayıtları; nitel verilerin toplanmasında ise yarı yapılandırılmış görüşme formları kullanılmıştır. Elde edilen nicel veriler ilişkisiz örneklem t testi ve tek yönlü varyans analizi (ANOVA) ile, nitel veriler ise içerik analizi ile çözümlenmiştir. Araştırma sonucunda 5. sınıf öğrencilerinin uzaktan eğitim sürecinde İngilizce başarı düzeylerinin ortanın üstü bir düzeyde olduğu belirlenmiştir. Ayrıca kız öğrenciler ile erkek öğrenciler arasında kız öğrenciler lehine anlamlı bir farklılık olduğu saptanmıştır. Genel akademik başarı düzeyi ve okuduğu okulun sosyoekonomik durumu yüksek olan ve canlı derslere sürekli katılan öğrencilerin İngilizce başarı testinden daha yüksek puanlar aldıkları belirlenmiştir. Bununla birlikte uzaktan eğitim sürecinde öğrencilerin teknoloji, canlı derslere katılma, işlenen ders, ödevler, ölçme ve değerlendirme ile ilgili sorunlar; öğretmenlerin ise teknoloji, ders içeriğinin sunumu, sınıf yönetimi, ölçme-değerlendirme ve veli ile ilgili sorunlar yaşadıkları tespit edilmiştir.
ORTAOKUL ÖĞRENCİLERİNİN UZAKTAN EĞİTİM ALGILARININ İNCELENMESİ: BİR KARMA YÖNTEM ARAŞTIRMASI
Authors: SALMAN Murat , AKAY Cenk
Published: May 2022

Bu çalışmanın amacı ortaokul öğrencilerinin uzaktan eğitim algılarını incelemek ve uzaktan eğitim ile ilgili görüşlerini ortaya koymaktır. Araştırmanın yöntemi nitel ve nicel araştırma yöntemlerinin bir arada kullanıldığı karma yöntem, deseni ise yakınsayan paralel desendir. Veri toplama aşamasında nicel veriler tarama modeli yoluyla, nitel veriler ise açık uçlu sorular yoluyla elde edilmiştir. Çalışmanın nicel aşaması, 2020-2021 eğitim öğretim yılı ikinci döneminde Mersin ili merkez ilçelerindeki beş ortaokuldan 254 kız ve 196 erkek olmak üzere toplam 450 öğrencinin katılımıyla gerçekleştirilmiştir. Çalışmaya katılan öğrencilerin uzaktan eğitim algılarını belirlemek için “Ortaokul Öğrencileri Uzaktan Eğitim Algıları Ölçeği” uygulanmıştır. Çalışmanın nitel aşamasında ise toplam 25 öğrenciden açık uçlu sorulardan oluşan bir form ile veri elde edilmiştir. Araştırma sonucunda ortaokul öğrencilerinin uzaktan eğitim algılarında cinsiyet, teknik olanaklar ve kullandıkları cihaza göre anlamlı bir fark olmadığı ortaya çıkmıştır. Fakat öğrencilerin sınıf seviyeleri, yaşları, internet sorunları, EBA sistemindeki sorunlar ve uzaktan eğitimi izledikleri yere göre uzaktan eğitim algılarında anlamlı farklılıklar olduğu tespit edilmiştir.
İLKOKUL ÖĞRETMENLERİNİN KAYNAŞTIRMA UYGULAMASINA İLİŞKİN TUTUMLARI VE YETERLİLİK ALGILARI: BİR KARMA YÖNTEM ARAŞTIRMASI
Authors: AKDEMİR Bora , ÇAPAR Emine , BAYRAKDAR Murat
Published: May 2022

Bu çalışma ilkokul öğretmenlerin kaynaştırma uygulamalarında tutumları ile yeterlilik algılarını incelemek amacıyla yürütülmüştür. Bu bağlamda açımlayıcı sıralı karma yöntem desenine göre öncelikle nicel veriler toplanarak ilişkisel tarama yaklaşımı içerisinde istatistiki olarak analiz edilmiştir. Elde edilen bulguları derinleştirmek amacıyla nicel araştırma katılımcılarından gönüllü olan öğretmenlerle odak grup görüşmeleri yapılmıştır. Nitel veriler tematik analiz yaklaşımıyla analiz edilmiş, nicel ve nitel bulgular birlikte tartışılmıştır. Araştırmanın nicel boyutuna 116, nitel boyutuna ise 7 öğretmen katılmıştır. Araştırma bulgularına dayalı olarak katılımcı öğretmenlerin kaynaştırma uygulamalarına yönelik duygu, tutum ve kaygı puanlarının ortalama seviyede olduğu ve bu verilerin nitel bulgularla belirli farklar içerdiği, algılanan yeterlilik puanlarının ise görece yüksek olduğu ancak bu alandaki nitel bulgularla ciddi farklılıklar içerdiği, duygu, tutum ve kaygı puanları ile algılanan yeterlilik puanları arasında negatif yönlü anlamlı bir ilişki olduğu bulgularına ulaşılmıştır. Bulgulara dayalı olarak uygulamacılara ve ileri araştırmalara yönelik öneriler getirilmiştir.
Prognostic value of systemic inflammatory response syndrome after transcatheter aortic valve implantation
Authors: Monosilio Sara , Filomena Domenico , Cimino Sara , Birtolo Lucia Ilaria , Tocci Marco , Mancone Massimo , Sardella Gennaro , Fedele Francesco , Maestrini Viviana , Agati Luciano
Published: May 2022

Aims

Systemic inflammatory response syndrome (SIRS) could affect mortality after transcatheter aortic valve implantation (TAVI) up to 12 months of follow-up. The aim of this study was to evaluate the prevalence of SIRS after TAVI and its impact on all-cause mortality up to 24 months follow-up.

Methods

We retrospectively enrolled 132 patients with symptomatic severe aortic stenosis undergoing TAVI. SIRS development during the first 72 h after the intervention was evaluated. Other postoperative complications were defined according to the Valve Academic Research Consortium 2 (VARC2). All patients underwent follow-up at 30 days and 24 months. Endpoints were 30-days and 24-months mortality.

Results

Post-TAVI SIRS developed in 27 patients (20%). At 30-day follow-up, all-cause death occurred in 10 (8%) patients and SIRS occurred more frequently in patients with adverse short-term outcome (60 vs. 17%; P = 0.001). Twenty-four months all-cause death occurred in 25 (19%) patients. SIRS resulted as an independent predictor of long-term outcome [hazard ratio 3.7; 95% confidence interval (95% CI) 1.5–9; P = 0.004], along with major vascular complications (hazard ratio 4; 95% CI 1.6–9.9; P = 0.003), relevant bleedings (hazard ratio 6.4; 95% CI 1.5–28; P = 0.013) and baseline pulmonary hypertension (hazard ratio 2.4; 95% CI 1.05–5.6; P = 0.039).

Conclusion

Postoperative SIRS was more frequent in patients who died at 30 days follow-up. Moreover, SIRS resulted as a predictor of 24-month mortality along with vascular complications, relevant bleedings and baseline pulmonary hypertension.
Escherichia coli pada Swab Rektum Ikan Koi yang Dipelihara di Kolam Isolasi pada Masa Karantina
Authors: Widiarta Kadek Apriyan , Mahatmi Hapsari , Gelgel Ketut Tono Pasek
Published: May 2022

Ikan koi (Cyprinus carpio) merupakan salah satu komoditas ikan hias air tawar yang memiliki nilai ekonomi dan peminat yang sangat tinggi. Ikan koi umumnya diantar pulaukan melalui darat, Kondisi ini dapat menyebabkan koi menjadi stress, yang berdampak pada penurunan kesehatan bahkan munculnya penyakit. Salah satu indikator gangguan kesehatan koi dapat dilihat dari adanya E.coli. Penelitian ini bertujuan untuk mengetahui bakteri Escherichia coli pada ikan koi yang dipelihara di kolam isolasi pada masa karantina dengan menggunakan 19 sampel isolat feses dari swab rektum yang kemudian dibawa ke BBVET Denpasar untuk dilakukan isolasi dan identifikasi bakteri E. coli. Penelitian ini menggunakan rancangan observasi eksploratif dengan metode cross sectional sedangkan sampel diambil dengan cara pusposive sampling. Serta data yang diperoleh disajikan secara deskriftif kualitatif. Hasil pada penelitian ini diketahui dari 19 sampel yang diperiksa menunjukan lima sampel positif bakteri Escherichia coli (26,3%) diantaranya tiga sampel (15,9%) berasal dari koi Tulungagung dan dua sampel (10,3%) berasal dari koi Blitar.
Efek Pemberian Sediaan Salep Ekstrak Daun Binahong secara Dermal pada Luka Insisi
Authors: Samirana Putu Oka , Sudimartini Luh Made , Sumadi I Wayan Juli , Wilantari Putu Dessy
Published: May 2022

Luka insisi merupakan luka yang terjadi karena teriris oleh instrumen yang tajam, misalnya luka yang terjadi setelah pembedahan atau operasi. Penelitian ini bertujuan untuk mengetahui efek pemberian sediaan salep ekstrak daun Binahong pada penyembuhan luka insisi. Daun Anredera scandens (L.) Moq. diekstraksi menggunakan etanol 70%, dan ekstraknya dibuat salep dengan basis adeps lanae dan vaselin album. Sebanyak 35 ekor tikus putih betina galur wistar umur 2-3 bulan dengan bobot 200 g dan diaklimatisasi selama satu minggu, dikelompokkan menjadi 7 kelompok perlakuan. Semua kelompok dibuat luka insisi pada bagian punggung sejajar tulang vertebra, kecuali pada kelompok normal. Setiap hari diberikan salep sebanyak dua kali sehari sebanyak 250 mg. Parameter yang diamati dari histopatologi kulit setelah diberikan salep adalah infiltrasi sel radang dan pembentukan kolagen Hasil penelitian menunjukkan bahwa pemberian salep ekstrak etanol daun A. scandens (L.) Moq. menunjukkan bahwa pada hari ke-21 masih terdapat sel radang yang tidak berbeda bermakna (p>0,05) pada semua kelompok dan pada konsentrasi ekstrak 40% terjadi pembentukan kolagen yang berbeda bermakna (p<0,05). Disimpulkan salep ekstrak etanol daun A. scandens (L.) Moq. belum mampu mengurangi sel radang setelah 21 hari perlakuan dan pada konsentrasi 40% menunjukkan pembentukan kolagen paling signifikan.
Prevalensi dan Intensitas Infeksi Cacing Strongyloides ransomi pada Babi yang Dipotong di Rumah Potong Hewan Pesanggaran Kota Denpasar
Authors: Akbar Muhammad Wilmar , Suratma Nyoman Adi , Oka Ida Bagus Made
Published: May 2022

Penelitian ini bertujuan untuk mengetahui prevalensi dan intensitas infeksi cacing Strongyloides ransomi pada babi yang dipotong di Rumah Potong Hewan Pesanggaran Kota Denpasar. Penelitian ini menggunakan 200 sampel feses babi. Pemeriksaan sampel feses untuk mengetahui prevalensi infeksi menggunakan metode apung sedangkan untuk mengetahui intensitas infeksi menggunakan metode Mc Master. Data yang diperoleh disajikan secara deskriptif. Hasil penelitian menunjukkan bahwa prevalensi infeksi cacing S. ransomi pada babi yang dipotong di Rumah Potong Hewan Pesanggaran Kota Denpasar sebesar 5% dengan intensitas infeksi berdasarkan hasil perhitungan total telur per gram (EPG) didapatkan hasil kurang dari 500 butir telur per gram feses sehingga dikategorikan hanya mengalami infeksi ringan.
Analisis Marka Gen Patogenik hlyF pada Escherichia coli Penyebab Kolibasilosis pada Ayam Buras
Authors: Chandrawan I Gede Eka , Mahardika Gusti Ngurah Kade , Besung I Nengah Kerta , Suarjana I Gusti Ketut
Published: May 2022

Kolibasilosis merupakan penyakit bakteri pada unggas yang disebabkan oleh Avian Pathogenic Escherchia coli (APEC) Kemampuan APEC untuk menyebabkan penyakit tergantung pada faktor virulensi, salah satunya adalah gen patogenik hlyF yang ada dalam plasmid. Penelitian bertujuan untuk membuktikan keberadaan gen hlyF APEC di Bali dan mengetahui sekuen DNA dari gen hlyF tersebut serta kekerabatannya dengan gen hlyF dari negara lain. Penelitian ini menggunakan dua isolat APEC asal ayam buras di Kabupaten Tabanan dan Badung  yang telah dimurnikan. Dalam penelitian ini, gen hlyF berhasil diamplifikasi dengan Panjang sekitar 600 bp.  Kedua hasil sekuen gen hlyF yang dapat dibaca dengan baik memiliki homologi 100% dengan panjang 518 bp. Analisis filogenik dengan 25 data gen hlyF pada Escherichia coli dan bakteri lain di dunia menggunakan metode UPGMA dengan bootstrap (500 pengulangan). Seluruh data memiliki enam situs polimorfik pada tingkat asam nukleat dan dua tingkat asam amino. Gen hlyF asal Bali berada didalam satu kelompok dengan gen hlyF isolat E. coli dari berbagai negara di dunia. Gen ini dapat digunakan sebagai marker patogenik APEC di Indonesia.
Dapatkah Kepemilikan Institusional Memoderasi Pengaruh Perencanaan Pajak Terhadap Kualitas Laba?
Authors: Christabelle Angelica , Trisnawati Estralita , Firmansyah Amrie
Published: May 2022

This study aims to obtain empirical evidence regarding the effect of managerial ownership, tax planning, and information asymmetry on earnings quality with institutional ownership as a moderating variable in Property and Real estate Companies listed on the Indonesia Stock Exchange for the 2017-2019 period. The sampling technique used was purposive sampling method. The company sample is 13 companies with 3 years of observation, then 39 observations are obtained. The data analysis technique used multiple regression for panel data. The results show that managerial ownership has a positive effect on earnings quality and institutional ownership is able to moderate the effect of managerial ownership and tax planning on earnings quality. This research indicates that the tax authorities in Indonesia should update and improve the existing system so that they can better monitor the actions of taxpayers.

Keywords: Managerial Ownership; Tax Planning; Institutional Ownership; Earnings Quality.
Apakah Profitabilitas Memoderasi Pengaruh Penghindaran Pajak Terhadap Nilai Perusahaan? Bukti Empiris dari Indonesia
Authors: Rahman Arief , Astuti Ayu Tri
Published: May 2022

The purpose of the study was to examine the effect of tax avoidance and audit quality on firm value with profitability as a moderating variable. Measurement of tax avoidance is carried out using the Effective Tax Rate (ETR). Meanwhile, audit quality uses a dummy indicator, namely the classification of the Big Four KAP auditors and KAP auditors Other than the Big Four and profitability is measured using Return on Assets (ROA). This study involved a sample of 54 companies that were registered on IDX in 2015-2019. The analysis technique used is Moderated Regression Analysis (MRA). The results showed that tax avoidance had no effect on firm value, although audit quality had a positive effect on firm value. The moderating variable for profitability affects the relationship between tax avoidance and firm value, but the moderating variable for profitability does not affect the relationship between audit quality and firm value.

Keywords: Tax Avoidance; Profitability; Firm Value; Audit Quality.
Pengaruh Work-Family Conflict Terhadap Turnover Intention dengan Burnout Sebagai Variabel Pemoderasi
Authors: Putra A. A. Ngr Gde Punia Artawan , Putra I Nyoman Wijana Asmara
Published: May 2022

This study aims to determine work-family conflict and burnout can affect turnover intention with burnout being the moderating variable. The location of the research was carried out in all Tax Consultant Offices in Bali. The population of confirmed tax consultant employees is 335 people by taking a sample of 77 using purposive sampling method. The study used primary data obtained from questionnaires distributed to each respondent and then regression was performed using moderate regression analysis (MRA). The results of data processing show that the work-family conflict and burnout variables have a positive effect on turnover intention, and burnout is able to moderate and strengthen the influence that occurs between work-family conflict on turnover intention.

Keywords: Work-Family Conflict; Burnout; Turnover Intention.
The Performance of Renewable Energy Companies Before and After Initial Public Offering
Authors: Ramadhan Prasetyo
Published: May 2022

The aim of this research is to analyze the differences in the performance of renewable energy companies before and after the Initial Public Offering (IPO). This research uses Paired Sample T-test as a data analysis method. The population in this study is a renewable energy company that conducts an IPO on the Indonesia Stock Exchange with a total of 3 companies. The sampling technique in this study uses purposive sampling and gets 2 samples. The results of this research indicate that there is no significant difference in the performance of renewable energy companies before and after the IPO. This could be due to the high initial investment costs in the renewable energy industry, the Government's low attention and utilization of renewable energy and the quality of management.

Keywords: Renewable Energy Companies; Performance; Initial Public Offering.
Struktur Aset, Ukuran Perusahaan, Likuiditas, Profitabilitas, dan Nilai Perusahaan
Authors: Grediani Evi , Dianingsih Mita
Published: May 2022

This study aims to examine the factors that affect firm value. The data used in this study are trading companies listed on the Indonesia Stock Exchange between 2016-2020. The data sampling technique was purposive sampling. The data was obtained from the web of trading companies and the website of the Indonesian stock exchange. Testing the research hypotheses using regression analysis using SPSS 26. The results show that firm size and profitability affect firm value. While the variable structure of assets and liquidity have no effect on firm value. Research contributes to investors in assessing companies related to the transparency of the company's financial reporting.

Keywords: Structure; Firm Size; Liquidity; Proitability; Firm Value
Determinan Nilai Perusahaan Sub Sektor Perbankan di Bursa Efek Indonesia
Authors: Fauzi Muhammad , Nurmatias Nurmatias
Published: May 2022

This study aims to determine the effect of capital structure, liquidity, and capital adequacy on firm value. The research population is the financial sector listed on the Indonesia Stock Exchange (IDX) in 2016-2020. The sampling technique used purposive sampling technique so that 180 research observations were obtained. The research analysis used panel data regression with the Eviews version 12 application and a significance level of 5%. The results showed that capital structure had a positive effect on firm value, liquidity had a negative effect on firm value, and capital adequacy had a positive effect on firm value.

Keywords: Capital Structure; Liquidity; Capital Adequacy; Firm Value.
Analisis Kinerja Keuangan Perusahaan BUMN Sebelum dan Sesudah Privatisasi
Authors: Syadiah Halimatus , Siswanto Ely
Published: May 2022

Privatization is one of the steps taken by State-Owned Enterprises (BUMN) in an effort to be able to compete and participate in capital market competition. The purpose of this study is to test whether there are differences in the financial performance of state-owned companies before and after privatization. The purposive sampling method was used in taking samples from BUMN that did privatization and had complete annual financial reports for a period of 3 years before and 3 years after privatization. Data analysis was carried out by analyzing descriptive statistics and inferential analysis which were tested by normality test and then hypothesis testing using STATAMP.15. The test results found that the Current Ratio (CR), Debt to Asset Ratio (DAR), Total Asset Turnover Ratio (TATO), Return on Equity (ROE) and Earning Per Share (EPS) had significant differences before and after privatization. Meanwhile Sales Growth (SG) did not find any difference before and after privatization.

Keywords: BUMN; Privatization; Financial Performance; IPO.
Covid-19 dan Volatilitas Harga Saham Melalui Peran Mediasi Harga Emas
Authors: Sarwindah Sarwindah , Hidayat Widi , Murni Siti Asiah
Published: May 2022

This study aims to analyze the effect of Covid-19 which consists of the number of positive cases, the number of deaths, and the number of recoveries on stock price volatility through the mediating role of gold prices. The research population is a retail company listed on the Indonesia Stock Exchange with a research period from April 2020 to June 2021. The research sample was taken using purposive sampling, and analyzed using SEM PLS. The results of the analysis show that the number of positive cases has a significant negative effect on gold prices and the volatility of retail companies' stock prices. The number of deceased has a positive effect on the price of gold and the volatility of the stock price of retail companies. The number of recoveries has a positive effect on gold prices, but has no significant effect on stock price volatility. The mediating role explains that the price of gold has a mediating role on the effect of the number of positive cases and the number of deaths on stock price volatility, but does not have a mediating role on the effect of the number of recoveries on stock price volatility.

Keywords: Covid-19; Gold Prices; Stock Price Volatility; Retail Companies.
Profitabilitas, Good Corporate Governance, Pengungkapan Corporate Social Responsibility dan Nilai Perusahaan
Authors: Laksmi Anak Agung Sagung Dewi , Wirawati Ni Gusti Putu
Published: May 2022

This study aims to obtain empirical evidence regarding the effect of profitability, good corporate governance, and disclosure of corporate social responsibility on firm value. The research was conducted on oil palm plantation companies listed on the Indonesia Stock Exchange for the 2016-2020 period. Purposive sampling is the technique of determining the sample chosen in this study and obtained a sample of 13 companies with a sample of 65 observations. The data analysis technique used is multiple linear regression analysis. Based on the research results obtained evidence, profitability has a positive and significant effect on firm value, good corporate governance has a positive but not significant effect on firm value, and disclosure of corporate social responsibility has a negative and insignificant effect on firm value.

Keywords: Profitability; Good Corporate Governance; Corporate Social Responsibility Disclosure; Firm Value.
Directive Illocutionary Acts Found in the Movies 21 And 22 Jump Street
Authors: Wisnu Adi Putra I Putu , Sedeng I Nyoman
Published: May 2022

This research is entitled Directive Illocutionary Acts found in The Movie 21 and 22 Jump Street. The purpose of this research is to identify the classification and the force of the speaker’s utterance that were found in the movie. The data were collected by applying the documentation and note taking techniques, and was analyzed by descriptive qualitative method. The speech acts theory was used to answer the problems of this research. It includes the types of directive illocutionary act proposed by Bach and Harnish (1979), and IFIDs proposed by Yule (1996). In this research, all of the direct directive acts were found. Meanwhile, only five types of indirect directive act were found except indirect questions. The illocutionary force of directive acts that were found are requesting, asking, forbidding, permitting, commanding, warning, prohibiting, ordering, and suggesting. The illocutionary force expressed by the speaker was considered felicitous if all the illocutionary force are fulfills
Dampak Pemilihan Lokasi terhadap Arsitektur Bangunan Benteng Karang Bolong di Pulau Nusakambangan
Authors: Suciningrum Putri Rizqi , Bawono Rochtri Agung , . Kristiawan
Published: May 2022

This article discusses the impact of site selection on the architecture of the Karang Bolong Fort. Data collection was done by using observation, interviews, and literature studies techniques. The research uses the analysis techniques of the outside of the buildings and qualitative analysis. The supporting theory used is the theory of landscape architecture. The results of this study provide an overview of site selection of Karang Bolong Fortress which affect the architecture form of the fort. Seeing the location, the Dutch East Indies government chose to adapt the Napoleon Tower model with some adjustments in the function and number of rooms. The architectural shape of the defense tower was chosen because it is in accordance with the function of Karang Bolong Fort as a defensive fortress on the east coast of Nusakambangan Island.
Flouting Grice’s Maxim in Jumanji: The Next Level
Authors: Vahini Putu Prasanthi , Budiarsa Made , Netra I Made
Published: May 2022

The title of this study is Flouting Grice Maxim in Jumanji: The Next Level. This study aims to analyze the types of maxim flouting in the film and analyze the reasons for the flout. Data obtained from the film Jumanji: The Next Level, directed by Jake Kasdan. The data were obtained from the film Jumanji: The Next Level using the documentation method and note-taking technique. Data were analyzed using descriptive qualitative methods. This study uses the theory of Grice (1975) cooperative principle. The result showed that the maxim that mostly flouted is the maxim of relation.
Visual and Verbal Sign in RM and Wale Music Video “Change”
Authors: Amara Salsabila Husna Ramadhani , Budiarsa Made , Rajeg Gede Primahadi Wijaya
Published: May 2022

The writing of  “Visual and Verbal Signs in RM and Wale Music Video Change” is to identify the types of visual communication elements and to analyze the meaning in visual and verbal communication elements. The data was collected by documentation method, note-taking technique and by downloading the music video, watching and listening carefully and finding the signs and classifying the data according to the types. In analyzing the data, the theory of visual communication proposed by Dyer (1993) and theory types of meaning proposed by Leech (1983) were used. The finding of analysis shows 15 elements in six visual categories. They include appearance (age, gender, national & racial, hair, body & size, look), manner (expression, eye contact, pose, & clothes), activity (touch, body movement, positional communication), props and setting. While in verbal representation of the Change music video clip findings seven meanings including conceptual meaning, connotative meaning, social meaning, affective meaning, reflected meaning, collocative meaning and thematic meaning.
Causes of anemia in patients with gastric cancer during the perioperative period
Authors: Giparovich M. A. , Khanevich M. D. , Yuryev E. Yu. , Alborov A. E. , Shilova E. R.
Published: May 2022

The OBJECTIVE of the study was to reveal the causes of anemia in patients with gastric cancer in the perioperative period.

METHODS AND MATERIALS. The object of the study were 700 patients with gastric cancer who underwent surgical treatment. All patients underwent clinical and biochemical blood test, indicators characterizing iron metabolism in the body (serum iron, ferritin, transferrin), and the level of endogenous erythropoietin during the perioperative period. The comparison group included 20 patients with gastric bleeding of non-neoplastic etiology. Both groups were comparable in age (median was 60 and 62 years old) and hemoglobin level (median Hb 95.3 g/l and 94.5 g/l).

RESULTS. Anemia was diagnosed in 15 % of patients (n=105) in the perioperative period. Mild anemia was more often detected (hemoglobin level 95–110 g/l) – in 47.6 % of patients. Moderate anemia (80–94 g/l) was observed in 24.0 % of patients, severe anemia (65–79 g/l) – in 18.1 % of patients, severe (hemoglobin level below 65 g/l) – in 10.3 % of patients. A strong correlation (r=0.89; P<0.05) was observed between the stage at the tumor process and the severity of anemia. At the same time, no connection was found between the macroscopic form of a stomach tumor and the severity of anemia. The analysis of the indicators of iron metabolism allowed to confirm the true iron deficiency in this category of patients, which was characterized by a decrease in the level of serum iron in patients with gastric cancer to (7.8±1.6) μmol/L (from 4.7 to 8.2 μmol/L). Comparative analysis of the level of endogenous erythropoietin in the group of patients with gastric cancer (n=20) and patients with gastrointestinal bleedings of non-neoplastic etiology (n=20) showed significantly lower values   with a difference of 27.7 % in the first group of patients ((66.9±28.2) mIU/ml versus (95.6±36.7) mIU/ml; P<0.05), which indicated inadequate production of erythropoietin in patients with gastric cancer.

CONCLUSION. The main causes of anemia in patients with gastric cancer in the perioperative period should be considered a true iron deficiency, as well as inadequate production of endogenous erythropoietin.