bluuebunny/crossref_metadata_2025 huggingface dataset:
Karakteristik Tegakan Hutan Tanaman Jati di Wilayah Kesatuan Pengelolaan Hutan Kabupaten Kupang
Authors: Almulqu Aah Ahmad , Renoat Emy
Published: August 2022

Kegiatan pengelolaan hutan tanaman jati merupakan salah satu faktor yang dapat mempengaruhi karakteristik tegakan hutan, misalnya untuk kegiatan penebangan yang tidak sesuai dengan konsep riap dapat berdampak pada perubahan kondisi karakteristik dan berpengaruh terhadap potensi  tegakan hutan jati untuk siklus tebang berikutnya. Penelitian ini bertujuan untuk mendapatkan gambaran tentang karakteristik tegakan hutan jati di kawasan Kesatuan pengelolaan Hutan (KPH) Kabupaten Kupang Provinsi Nusa Tenggara Timur. Dengan kegiatan penelitian ini diharapkan dapat diketahui kondisi terkini tegakan jati, kemudian digunakan untuk menduga kondisi tegakan jati pada masa yang akan datang dengan memperhatikan riap dan dinamika struktur tegakannya. Dari penelitian ini dapat diketahui bahwa di areal hutan tegakan jati di KPH Kabupaten Kupang memiliki keragaman karakteristik tegakan dalam hal jumlah pohon, diameter, tinggi dan volume pohon jatinya. Secara keseluruhan diperoleh jumlah pohon pada klaster pengamatan sebanyak 268 pohon jati (Klaster 1= 91 pohon, Klaster 2 = 87 pohon dan Klaster 3 = 90 pohon). Perlu kajian lebih lanjut untuk mengetahui perkembangan tegakan pada masa yang akan datang berdasarkan pengamatan dan pengukuran terhadap petak ukur permanen (PUP), selanjutnya informasi tersebut dapat digunakan sebagai bahan pertimbangan dalam penentuan sistem silvikultur pada rotasi tebang berikutnya.
The Spring Insects Diversity in Mutis Timau Nature Reserve
Authors: Semiun Chatarina Gradict , Duhan Gaudensius U.U.Boli
Published: August 2022

Insect diversity is believed to be used as a bio-indicator of spring quality. This study aimed at determining the spring insect diversity around the Mutis Timau Nature Reserve. The study was conducted from June to August 2019. Insects were caught by using the yellow pan trap and hand sorting. The diversity of spring insects was determined based on the Shannon-Wienner diversity index (H'), species richness index (R1), species dominance index (D), and evenness index (E). The results showed that 16 species belong to 11 families, and 5 orders of insects. The families included Gryllidae, Gryllotalpidae, Tetrigidae, Formicidae, Pompilidae, Apidae, Ochteridae, Veliidae, Hydrometridae, Nepidae, Coenagrionidae, Libellulidae, Carabidae, and Coccinellidae. The Shannon-Wiener species diversity index and the wealth index of the species of springs were classified as moderate (H '= 2.12 and R1 = 4.19). There was no type of spring insects dominated (D = 0.23). All springs insects were found to have almost the same level of evenness (E<1), with a value of 0.76. Abiotic factors such as pH and soil temperature were within the tolerance range of spring insects.

 

Key words: Insects diversity, Spring, Mutis Timau Nature Reserve
Hubungan Kesadaran Metakognitif Peserta Didik Dengan Hasil Belajar Biologi
Authors: Asaidah Ai Anisa , Mustofa Romy Faisal , Chaidir Diki Muhamad
Published: August 2022

This study aims to determine the correlation of metacognitive awareness with biology learning outcomes of students in class XI IPA MA Negeri 1 Tasikmalaya City which was conducted in May 2021. This research is a correlational study. The population in this study were all students of class XI IPA MA Negeri 1 Tasikmalaya City as many as 4 classes. The sample selection in this study used a purposive sampling technique as many as 67 students of class XI IPA 3 and class XI IPA 4. The data collection techniques used in this study were questionnaires and interviews. The results of data analysis showed that there was a relationship between metacognitive awareness and biology learning outcomes with a correlation coefficient value of 0.531 meaning that it had a moderate correlation, and a significance value of 0.000 <0.05 was obtained. The conclusion of this study is that there is a relationship between metacognitive awareness and learning outcomes of biology class XI IPA MAN 1 Tasikmalaya City.
Hubungan Self Efficacy dan Kemandirian Belajar Terhadap Hasil Belajar Siswa Pada Materi Sel
Authors: Rachman Shinta Aulia , Mustofa Romy Faisal , Diella Dea
Published: August 2022

This study aims to determine the correlation between self-efficacy and learning independence on student learning outcomes in cell material in XI Math and Science class of 6 Senior High School Tasikmalaya in the 2021/2022 academic year. The method in this study uses the correlational method. The population this research of class XI MIPA SMAN 6 Tasikmalaya in the 2021/2022 academic year. The sample used was class XI MIPA 5 and XI MIPA 7 for the academic year 2021/2022 with a total of 72 students, the sample was taken using purposive sampling technique. Data collection techniques used tests in the form of daily tests of cell material and non-tests in the form of instruments self-efficacy questionnaires and learning independence questionnaires. Hypothesis testing using multivariate correlation test. The results of the correlation test analysis show that the relationship between self-efficacy and learning independence on student learning outcomes is obtained by a correlation coefficient (R) of 0.489, which means that the strength of the relationship between variables is at a moderate level, and the coefficient of determination (R2) is 0.239, which means that the variables of self-efficacy and learning independence are variable. collectively contributed 23.9% to student learning outcomes
Analisis Buku Ajar Biologi SMA Kelas XI Materi Sistem Peredaran Darah dan Sistem Endokrin
Authors: Nisaa Ranti An , Maesaroh Maesaroh
Published: August 2022

The majority of textbooks are used as the main source of learning in the classroom. The National Education Standards Agency and the Book Center require that every textbook has met certain standards that it has set in accordance with the needs, curriculum, and developments in science and technology. The purpose of the study was to determine the suitability of the material on the circulatory system and endocrine system in biology textbooks with the demands of competence in the curriculum. This study uses a descriptive method with a qualitative approach. The results showed that the material on the circulatory system and endocrine system was sufficient to meet the Basic Competencies (KD) contained in the curriculum and in accordance with the standards of the National Education Standards Agency (BSNP). There are some inaccuracies in the material presented. In the material on the endocrine system, several deficiencies were found in the presentation of concepts such as the explanation of the hormones ADH, FSH, LH, the pancreas gland, the thymus gland, and abnormalities due to certain hormone deficiencies. There are three typos, and in the supporting image there is a lack of image clarity and color.
Upaya Peningkatan Tanaman Buah Merah Papua (Pandanus conoideus) Dengan Berbagai Perlakuan Pupuk Organik Cair dan Pupuk Kompos di Kampung Mariadei
Authors: Rahanra Roy Marthen , Samber Loreta
Published: August 2022

Upaya dalam meningkatkan budidaya tanaman buah merah Papua dengan berbagai pupuk baik pupuk organik cair maupun pupuk kompos merupakan solusi dalam pengembangan buah merah di Papua. Tujuan dari penelitian ini adalah untuk melihat seberapa kuat pengaruh pupuk organik cair dan pupuk kompos dalam meningkatkan pertumbuhan tanaman buah merah di kampung mariadei. Metode yang digunakan dalam penelitian ini adalah Rancangan Acak Lengkap (RAL) yang terdiri dari 3 perlakuan dan 3 ulangan, sehingga terdapat 9 satuan percobaan dengan komposisi : A = kontrol tanah tanpa pupuk B = 0,25 liter pupuk organik cair/petak + 0,5 liter air, C =  Pupuk Kompos terdiri dari sayur-sayuran busuk sebanyak 30 kg, rerumputan sebanyak 20 kg, daun lamtoro sebanyak 20 kg ditambah dengan EM4. Dari hasil penelitian yang telah dilakukan, dapat disimpulkan bahwa adanya pengaruh yang terbaik pada pemberian Pupuk Organik Cair sedangkan Pupuk kompos memberikan dampak pertumbuhan bagi tanaman buah merah Papua belum signifikan.
PFC Simulation Study on Time-dependent Deformation Failure Properties and Energy Conversion Law of Sandstone under Different Axial Stress
Authors: Wang Yu , Liu Qi
Published: August 2022

Rock burst mostly happens in deep rock engineering, which obviously performs obvious time-dependent destruction and releases huge energy. Thus, the uniaxial compressive time-dependent deformation failure tests of sandstone under different axial stress are conducted and the optimized Parallel-bonded stress corrosion (PSC) model is established based on PFC method. The results show that tension micro-cracks are the direct reason of rock bearing capacity reduction during the whole failure process. The time-dependent deformation stage is composed of the initial strain stage, the steady-state strain stage and the accelerated strain stage. As the axial stress increases, rock mass enters into the accelerated strain stage more quickly and the strain amount of time-dependent deformation stage decreases. From the comparison of energy conversion between PFC simulation and experiments, the higher elastic strain energy will be accumulated and the less dissipation energy will be produced while the axial stress increases when reaching the failure point. After the failure point, the elastic strain energy has a small increase because the strain rate changes faster than the failure relaxation rate. Based on the calculation results of residual elastic energy index (AEF), the rock burst shows a tendency that from weakness to moderation as the axial stress increases. The research results will provide a certain reference in predicting the rock burst.
SOCIAL COMMUNICATION STRATEGIES IN PREVENTING TERRORISM IN THE REGIONAL OF DISTRICT MILITARY COMMAND 0618/BS BANDUNG CITY
Authors: Setyanto Endar
Published: August 2022

District Military Command 0618 / BS Bandung City as Satkowil (Territorial Unit) implements Social Communication as one of the methods of Territorial Development in its area. This study aims to analyze the ways of implementing social communication in the prevention of terrorism in the Regional of District Military Command 0618 / BS in Bandung and also how the Strategy for Implementing Social Communication to prevent terrorism in the Regional of District Military Command 0618 / BS Bandung. This research is a qualitative social study. Data sources used include primary data and secondary data. The technique of collecting data uses interviews, observation, and is supported by documentation and triangulation studies. Qualitative data analysis is performed by data reduction, data presentation and conclusions drawn. The study was conducted in the District Military Command 0618 / BS Bandung City, West Java. Based on this research, the results of the study of the Social Communication Coaching Strategy District Military Command 0618 / BS Bandung city can help the efforts to overcome terrorism in the area. The activities consist of giving lectures, advice and measurable data collection as well as the implementation of creative social media that is involved in the present. With this strategy, it can compete for the hearts of the people and create a unity of the TNI - the People. At the same time as an effort to deradicalise, a quick meeting and resistance against radical groups as a forerunner can be directed at acts of terrorism in the region. In the city of Bandung there are groups consisting of bed cells taken when they can appear and be developed and can be moved which can lead to conflict and terrorism. Counter terrorism must be carried out jointly with other parties and the Regional Government and the community in order to obtain maximum results.Keywords: Strategy, Social Communication , Region Command Unit, Terrorism, District Military Command
2nd AIR SCADRON STRATEGY INCREASING SUPPORT OF AIR DEFENSE OPERATIONS THROUGH WEATHER MODIFICATION TECHNOLOGY
Authors: Ngimron Fitrianto Ali , Toruan TS Lumban , Sianturi Dohar
Published: August 2022

The involvement of the Indonesian Air Force in Weather Modification Technology Operations is part of Military Operations Other than War. Along with the rapid development of technology in the field of Weather Modification which makes the use of this technology easier. One of the benefits of Operation Weather Modification Technology is to support Air Defense Operations. However, in several implementations there are several obstacles encountered, the Air Squadron is not yet equipped with a sophisticated weather radar. Today's weather radar requires a technology upgrade. The 2nd Air Squadron had problems carrying out TMC Operations at night. In order for the use of Weather Modification Technology to be used optimally for military operations and able to support air defense operations, an effective and efficient strategy is needed. The purpose of this study is to analyze the main obstacles, the implementation of Air Defense Operations, possible air threats and strategies to increase support for air defense operations through the use of Weather Modification Technology by the Air Squadron 2. The research method used is a qualitative case study design. Theories used include strategy, air power, weather manipulation and air defense operations. The results of this study are the main obstacles encountered related to the use of Air Squadron TMC are weather conditions, lack of raw materials and inadequate equipment. The conditions for the implementation of air defense operations are not optimal and there are several threats that can arise in the Indonesian air sovereignty area. The strategy used to achieve the goal is to overcome existing obstacles and improve the ability of the Air Squadron 2 through existing instruments. The conclusion of this study is that threats to air sovereignty can be anticipated by optimizing the Air Squadron 2's weather modification capabilities.Keywords : 2nd Air Squadron Ability, Air Defense Operations, Utilization, Strategy, Weather Modification Technology
114 THE UNMANNED AIRCRAFT CAPABILITIES IN INTEGRATED MARITIME DEFENSE TO SUPPORT WORLD MARITIME AXIS POLICY
Authors: Chaniago Yulmaizir , Yusnaldi Yusnaldi
Published: August 2022

Indonesian National Armed Forces, the Air Force, as a means of national defense , had the task of upholding the sovereignty of the unitary state of the Republic of Indonesia and the territorial integrity of country, especially in the context of upholding state sovereignty in the air, and supporting the enforcement of state sovereignty on land and at sea. In order to realize this, the Indonesian Air Force through one of its functions in its territorial development is through fostering the potential of aerospace, through the empowerment of defense areas. The development of aerospace potential is carried out as an effort to realize the creation of regional security around the base. This research method is a qualitative method with observation techniques, documentation studies and interviews. The results of the study showed that there are still a level of vulnerability of security in around Atang Senjaya Air Force Base area which is the concentration of local security forces, office complexes, personnel and facilities and infrastructure that require a fairly high level of supervision. The existence of military installations, whether complex or office buildings, is still quite open and easily accessible to parties with certain interests. It is very important to establish a condition of the expected defense area through the synergy of all territorial apparatus in optimally carrying out the development of aerospace potential in the community, through the role of Binpotdirga personnel, in providing guidance, conducting effective communication, and participation from local government.Keywords: Air base, empowerment, regional defense , universal defense system, Atang Sendjaja
34 ANCAMAN ASIMETRIS DALAM KERJASAMA BELT AND ROAD INITIATIVE DI INDONESIA
Authors: Palamani Siti Mawaddah
Published: August 2022

Kerjasama Belt and Road Initiative (BRI) di Indonesia dimulai pada tahun 2018 ketika Indonesia menandatangani MoU BRI dengan negara China. Kerjasama BRI yang berasal dari negara China telah mendapat banyak kritik atas jebakan hutang (debt trap) dan menjadi sebuah polemik dalam kerjasama ekonomi internasional. Permasalahan dalam penelitian ini adalah mengenai bagaimana kerjasama BRI dapat menajdi ancaman bagi Indonesia serta bagaimana strategi pertahanan negara Indonesia untuk mengantisipasi ancaman tersebut. Tujuan dari penelitian ini adalah untuk menganalisis kerja sama BRI oleh negara China yang dapat menjadi ancaman asimetris dalam kerjasama BRI ini serta menganalisis strategi pertahanan negara Indonesia dalam menghadapi ancaman tersebut. Metode dan desain yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan pendekatan analisis desktriptif. Hasil dari penelitian ini adalah dampak dari ancaman yang terdapat dalam kerja sama BRI bukan hanya pada bidang ekonomi namun juga pada sektor pertahanan. Dibutuhkan strategi yang mampu menangkal ancaman tersebut, dan pemerintah Indonesia harus memperhatikan contingency plan jika terjadi worst case dalam pelaksanaan kerja sama ini. Peneliti memberikan rekomendasi yaitu diperlukan adanya pengawasan dalam pelaksanaan kerja sama BRI di Indonesia, serta pengkajian ulang mengenai kerja sama ekonomi internasional.
PENGUATAN STRATEGI PERTAHANAN LAUT MELALUI PENINGKATAN KESIAPAN PRAJURIT PENGAWAK KAPAL PERANG REPUBLIK INDONESIA
Authors: Palupi Endah , Suhardono Edi , Bangun Ernalem
Published: August 2022

Strategi Pertahanan Laut dalam lingkup penangkalan salah satunya dengan menghadirkan kekuatan TNI AL di wilayah laut. Hal ini menuntut kesiapan Kapal Republik Indonesia (KRI) yang meliputi kesiapan material platform dan personelnya. Satuan kerja di KRI yang berbeda dengan kondisi di satuan di darat (pendirat) pada umumnya memerlukan penyesuaian diri dari masing-masing personel dan rekayasa kesehatan personel agar dapat terhindar dari gangguan kesehatan atau penyakit yang dapat mengganggu kinerjanya. Permasalahan penelitian yaitu tentang implementasi urikkes prajurit KRI di Diskes Koarmada I untuk kesiapan dalam rangka mendukung tugas pertahanan, faktor-faktor yang memengaruhi dan strategi terbaik yang dilakukan. Tujuan penelitian untuk menganalisa implementasi pemeriksaan kesehatan prajurit pengawak KRI di Diskes Koarmada I, faktor-faktor apa yang memengaruhi dan upaya apa yang dilakukan guna mendapat hasil pelaksanaan urikkes prajurit pengawak KRI yang optimal. Penelitian ini menggunakan metode kualitatif. Analisa menggunakan teori implementasi kebijakan dari George Edward III. Data diperoleh dari para informan yang terkait dengan penyelenggaraan urikkes untuk prajurit pengawak KRI di Koarmada I yang selanjutnya dianalisis dengan teknik analisis kualitatif. Hasil penelitian menunjukkan bahwa pelaksanaan urikkes prajurit pengawak KRI sudah terlaksana namun belum optimal. Upaya yang dilakukan adalah berkoordinasi di tahap perencanaan, perlu dibuat kebijakan yang mewajibkan prajurit KRI melaksanakan urikkes tanpa terkecuali (dinas/pendidikan) dan memberikan vaksinasi Covid-19 sesuai persyaratan kepada prajurit KRI. Sehingga prajurit KRI dapat bertugas secara optimal mendukung pertahanan laut negara.
In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia
Authors: Van Trimpont Maaike , Schalk Amanda M. , De Visser Yanti , Nguyen Hien Anh , Reunes Lindy , Vandemeulebroecke Katrien , Peeters Evelien , Su Ying , Lee Hyun , Lorenzi Philip L. , Chan Wai-Kin , Mondelaers Veerle , De Moerloose Barbara , Lammens Tim , Goossens Steven , Van Vlierberghe Pieter , Lavie Arnon
Published: August 2022

Asparagine is a non-essential amino acid since it can either be taken up via the diet or synthesized by asparagine synthetase. Acute lymphoblastic leukemia (ALL) cells do not express asparagine synthetase or express it only minimally, which makes them completely dependent on extracellular asparagine for their growth and survival. This dependency makes ALL cells vulnerable to treatment with L-asparaginase, an enzyme that hydrolyzes asparagine. To date, all clinically approved L-asparaginases have significant L-glutaminase co-activity, associated with non-immune related toxic side effects observed during therapy. Therefore, reduction of L-glutaminase co-activity with concomitant maintenance of its anticancer L-asparaginase effect may effectively improve the tolerability of this unique drug. Previously, we designed a new alternative variant of Erwinia chrysanthemi (ErA; Erwinaze) with decreased L-glutaminase co-activity, while maintaining its L-asparaginase activity, by the introduction of three key mutations around the active site (ErA-TM). However, Erwinaze and our ErA-TM variant have very short half-lives in vivo. Here, we show that the fusion of ErA-TM with an albumin binding domain (ABD)-tag significantly increases its in vivo persistence. In addition, we evaluated the in vivo therapeutic efficacy of ABD-ErA-TM in a B-ALL xenograft model of SUP-B15. Our results show a comparable long-lasting durable antileukemic effect between the standard-of-care pegylated-asparaginase and ABD-ErA-TM L-asparaginase, but with fewer co-glutaminase-related acute side effects. Since the toxic side effects of current L-asparaginases often result in treatment discontinuation in ALL patients, this novel ErA-TM variant with ultra-low L-glutaminase co-activity and long in vivo persistence may have great clinical potential.
Effects of e-marketing on customers patronage of commercial banks, a study of Guaranty Trust Holding Company PLC, Lagos
Authors: Abdulquadri Abdulazeez Olamide , Dixon-Ogbechi Bolajoko
Published: August 2022

This study examined the effects of E-marketing on customers’ patronage of commercial banks a study of Guaranty Trust Bank (GTBank) PLC, Lagos. The study adopted quantitative research design and the sources of data for this study were purely primary and secondary and a sample size of 385 customers of GTBank Plc, in Akoka area of Yaba Local Government, Lagos state were selected through a convenience sampling technique. The data were analyzed and descriptive statistics (mean and median), regression analysis and analysis of variance were used to provide answers to the research questions and test hypotheses. The study revealed that there is a direct nexus between the use of internet banking, and increase in customer patronage of GTBank, Plc, Lagos. Furthermore, a positive relationship was established between the use of USSD codes and quick service delivery of GTBank, Plc, Lagos. The study therefore conclude that E-marketing influences customers’ patronage of GTBank PLC, Lagos and it was recommended that GTBank PLC, Lagos should continue the utilization of its E-marketing components (i.e. Internet banking, and USSD codes) as this assist in serving their customers better through quick service delivery and also increases the utility enjoyed which encourage frequent patronage. Future researchers can make research on same topic but increasing the scope to other commercial banks in Nigeria for better comparison.
KARALAMA DEFTERİNDEN KENDİ METNİNE DOĞRU YAZARLIK UĞRAŞISINA BAKIŞ
Authors: TATAR KIRILMIŞ İlknur
Published: August 2022

Yazarlığın vazgeçilmez özelliklerinden birisi düzenli yazmak ve çoğu zaman yazılanları karalama kabul edip onlardan vazgeçebilmektir. Yazarların kendi eserlerine doğru yol alırken yaptıkları rutinler için başka yazarların metinlerini kullandıkları ve “yeniden yazma” tekniği olarak isimlendilen bu çalışmalardan bazılarını eserlerine taşıdıkları da görülür.Postmodern felsefenin tesiriyle yazarın kurmacasını tasarlama yönünü metninde sergilemesi, üstkurmaca tekniğini işlevsel bir duruma getirdiği gibi bu yolla farklı metinlerin yeniden yazılması okurun önünde gerçekleşir. Yeni Türk Edebiyatı çalışma sahasında giderek yeri sağlamlaşan yazarlık ve yazma eylemine yönelik araştırmalar mevcut metinleri farklı bir okumayla değerlendirmenin yolunu açtığı gibi yazmaya ilgi duyanlara teknik desteği kendiliğinden sağlamaktadır. Bu çalışma, Murat Gülsoy’un “Vazgeç” adlı öyküsünde yer alan yeniden yazmak tekniğinin yazma uğraşısına örneklik ettiği görüşüne odaklanmaktadır. Üstkurmaca tekniğinin sunduğu şeffaflık yoluyla pastişin metindeki kullanımı gözlemlenebilir bir bilgiye dönüşür. Bu araştırmadan elde edilen veriler, hem yazarlık çalışmaları hem de çağdaş edebiyat araştırmalarında kullanılabilecek farklı bir okuma tekniğini teklif etmektedir.
Behind the screens: the crystals that flow like rain down a windowpane
Authors: Bhadwal Akhshay , Cousins Joseph
Published: August 2022

Dr Akhshay Bhadwal, an experimental physicist, and Dr Joseph Cousins, a mathematician, are combining their skills and expertise to understand how nematic liquid crystals behave.
Acute Appendicitis: Correspondence Between Adult Appendicitis Score (AAS) and Intraoperative Survey as Assessed by the Questionnaire Obtained from the Laparoscopic Appendicitis Score (LAPP) in 102 Patients in a Single-Centre
Authors: Raffaele Porfidia , Simona Grimaldi , Giovanna Ciolli Maria , Pietro Picarella , Antonio Catauro , Sergio Grimaldi
Published: August 2022

Introduction: Despite advanced imaging techniques and several validated clinical prediction rules, correctly diagnosing a patient with acute appendicitis remains challenging. The AIR score and the AAS score 6 seem currently to be the best performing clinical prediction scores and have the highest discriminating power in adults with suspected acute appendicitis. The Laparoscopic Appendicitis Score 7 (LAPP) is an easily applicable score that can be used by surgeons to evaluate the appendix during diagnostic laparoscopy. Scope: The aim is to verify whether an increase in the AAS score corresponds to a worse intraoperative picture certified by the postoperative questionnaire. Materials and Method: 157 patients with abdominal pain localized in the right iliac fossa were observed. 102 patients (65%) were hospitalized with the diagnosis of acute appendicitis. Based on the AAS we divided the hospitalized patients into 3 groups. Results: In our case series we have shown that an increase in the AAS score always corresponds to a worse intraoperative picture.
Atrial Fibrillation is Not A Dead Horse
Authors: Patrizia Fiori , Lia Allegorico , Guglielmo Capaldo , Marco Massarelli , Raffaele Gizzi , Chiara Pelosi , Patrizia Savino , Annamaria Bellizzi , Giuseppe Bianchino , Filomena Botticella , Angela Di Gianni , Carmela Dragonetti , Pasquale Gualdiero , Carmela Lo Conte , Gianvito Manganelli , Stefania Minichiello , Alessandro Morella , Vincenzo Pellecchia , Gennaro Bellizzi , Marielisa Alberico , Giovanni Benigni , Terenzio Damiano , Monica De Caro , Erminio Pace , Maurizio Ferrara , Alberigo Martino , Emerico Mazza , Gigliola Esposito , Carminantonio Tammaro , Rocco Cusano , Michele Caraglia , Antonio Corbo , Antonio Monaco , Silvio D’Agostino , Angelo Frieri
Published: August 2022

Prevalence and incidence of Atrial Fibrillation (AF) is high in western countries. It is apparently lower in developing countries, because of unrecognition, undertreatment and related complications and mortality. Studies in subjects wearing cardiac implantable electronic devices showed a wide burden of AF, ranging from subclinical episodes to permanent AF. The aim of our study was to identify haematological and haemodynamic differences between Paroxysmal Atrial Tachyarrhythmias (PAT) compared to Non-Paroxysmal AF (NPAF), detected by 24 hours Holter ECG, and predictive negative factors associated with increased risk of evolution from paroxysmal to persistent or permanent AF. Our data highlight the dynamic nature of PAT and NPAF. PAT in young subjects is a red flag, requiring at least changes in lifestyle and further diagnostic examinations to avoid progression to irreversible pathological myocardial electrical and structural remodeling. Comorbidities, scarce compliance, or inappropriate treatments account for high incidence of acute cerebrovascular events with disabling outcomes in elderly patients. Further studies are needed on genetic susceptibility and vulnerability. Educational campaign is the most effective, long- term strategy. Personalized approach and therapeutical scheme are recommended based on patient compliance and actual risk. A holistic approach to patient is the pillar for any clinical decision and practice.
Suggestions of Slovenian Students on Ways to Acquire Dementia-Related Knowledge
Authors: Felc Brina
Published: August 2022

Objectives: Although the number of people with dementia is growing due to the aging population, knowledge of dementia among adolescents is unknown, as are their suggestions for how to acquire knowledge. Aim: To determine the knowledge of dementia among students and to identify their suggestions on to acquire dementia-related knowledge. Methods: An online cross-sectional study was conducted in order to determine the knowledge of dementia among students of non-medical high schools in Slovenia. The gender comparison of the knowledge and proposals for a way of educating were obtained. Results: A total of 1128 students (770 girls and 348 boys) aged 14 -19 participated in this study. The results indicated that of 20 claims of dementia, participants were on average able to answer 71.5% correctly (M = 14.30; SD = 2.56), girls better than boy (p<0.05), students with relative with dementia better than others (p<0.05). Proposals for ways of future dementia education did not differ between the sexes (p>0.05). Both, girls and boys in the same percentage indicated future priority learning methods namely: use of the Internet, learning in school lessons and from books and textbooks, learning from medical staff. Conclusions: Organizers and providers of dementia education for adolescents should organize as much education as possible via the Internet. Further research on the most appropriate form of dementia education among high school students is recommended.
Parental Practice of Providing Care for their Infants Receiving Vaccination: Pilot Study
Authors: Thongpong Duanphen , Virasiri Saovakon
Published: August 2022

Providing effective health care for infants who receive immunization is very of a strong necessity for their health and safety. According to immunization can cause adverse effects in various types, which call as Adverse Events Following Immunization (AEFI). The AEFI usually can occur in various types such as skin rash and redness, fever, and pain. In case of severe side effects; anaphylactic shock may occur. Therefore, parents need to provide health care for their young children. This pilot study was aimed at studying how parents provide care for their infants about vaccination at one hospital in Thailand. Ten parents of infants were purposive selection. Data were collected by interview and observation with record form. Data analysis was done through content analysis and descriptive statistic methods. The findings displayed all parents took their infants for vaccination without checking the names and benefits of the vaccines. Two grandmothers gave medicine for relieving the fever of their infants both before and after vaccination. During vaccination, eight parents could not hold their infants appropriately. Five parents did not know how to support their infants during the injection. One grandmother relieved the fever of her infant by soaking in warm water mixed with limejuice. Two grandparents applied the balm and herbal medicated oil for relieving edema and pain at the injection area. Three grandparents applied herbal powder at the vaccinated area to decrease inflammation. All of them did not know of and thus did not observe AEFI events. Ultimately, the pilot study reflects the limitation of knowledge, beliefs, and practice among parents in relation to vaccination care for their infants. Thus, nurses and health personnel should create and provide family health education for enhancing relevant knowledge, beliefs, and skills for parents of infants.
Chest Pain from Metabolic Origin
Authors: Ekladious Adel
Published: August 2022

Brown tumors are a rare non-neoplastic, osteolytic lesion caused by an increase in osteoclastic bone resorption. The increase in bone breakdown often leads to patients developing hypercalcemia and osteopenia as a result. Hypercalcemia associated with brown tumors arise due to primary, secondary, or tertiary hyperparathyroidism and in rare cases, occur from the development of a parathyroid gland carcinoma. Most cases of brown tumors are asymptomatic, however, on occasion it can present with pain or compressive symptoms. Common sites for these tumors include clavicle, ribs, pelvis, long bones, maxilla, and mandible. Additionally, it should be noted that brown tumors affect trabecular bone more frequently than cancellous bone. We will be looking at a 35-year-old male patient who presented with chest pain. He was investigated thoroughly with blood tests, echocardiogram, coronary angiogram, bone marrow trephine biopsy, whole body CT scan, CT- PET scan and finally with excision rib biopsy. Only upon the excision, rib biopsy was the diagnosis of brown tumor confirmed. The development of this tumor was determined to be secondary to primary hyperparathyroidism. Following surgical treatment for hyperparathyroidism, the brown tumor resolved spontaneously.
Serine Proteases and Their Inhibitors Affect the Rate of GnRH Neuronal Migration in the Embryonic Chick Model: A Thesis Proposal
Authors: Borokhovsky Benjamin , Nagengast Alexis
Published: August 2022

Development in an organism is a highly complex task that requires a specific sequence for proper function. One of these tasks is neuronal migration and the extracellular cues that help to guide neurons to their appropriate locations. If neurons do not migrate to their appropriate locations, then there are abnormal neural connections, which can result in neuronal migration disorders (NMD). It has been shown that the inhibition and stimulation of migration may be balanced due to effects of serine protease inhibitors and serine proteases. Serine proteases and their inhibitors can alter the various chemoattraction-signaling cues and thereby modulate neuronal migratory processes. Furthermore, there exists a delicate balance between serine proteases and their inhibitors to modulate migration of neurons within development. Thus, by understanding how the balance of serine protease and serine protease inhibitor activity works, one can further understand how these changes affect neuronal migration in development. Experiments to test in vivo neuronal migration of chick GnRH neurons during embryogenesis were investigated to elucidate the role these proteins play in migration. Protein coated beads were inserted and GnRH levels measured to control. Such experimentation is crucial, as these studies are the first to explore the role of proteases in neural migration in an in vivo model. These findings indicate that the ability to initiate migration lies inherently within the neuron itself such that changes of the extracellular matrix composition are irrelevant in the initial timing. Neurons entering the CNS earlier in trypsin-treated embryos indicates continuous movement may be a cell autonomous event with trypsin-induced proteolysis. In other words, the ability of GnRH neurons to migrate across glial boundaries and through the brain to its target site is independent of further maturation of the neuron or the brain. Taken together, this study can provide knowledge regarding these proteins and their relation to development. This knowledge can potentially lead to therapies that can provide ameliorative care for patients suffering with NMD.
The Impact of Enucleation of Unilateral Endometriomas on the Ovarian Reserve and Reproductive Function
Authors: Nugesha Grigalashvili
Published: August 2022

Background: The data concerning the impact of endometrial cystectomy on the ovarian reserve is controversial. It is not clear how the cyst size and women age influence the outcome of surgical intervention in participants with ovarian endometrioma. Objectives: The study was aimed to evaluate the impact of enucleation of unilateral endometriomas on the ovarian reserve and reproductive function with regard to cyst size and women age. Materials and Methods: The study included 60 participants aged 19-40 years, with unilateral endometrioma and infertility, who underwent laparoscopy. Study participants were divided into 2 groups by the size of cyst: <3 and ≥ 3 cm. Each group was divided into subgroups by the age of participants: <35 and ≥ 35 years. The serum level of anti-mullerian hormone and antral follicle count were determined before, after 1 and 6 months of cystectomy. The rate of pregnancy was recorded during 1 year of post-surgery. Results: The level of anti-mullerian hormone and antral follicle count were significantly low in participants aged ≥ 35. Ovarian reserve decreased in all participants after 1 month of surgery, restored after 6 months in younger women, but didn’t reach the preoperative level. The pregnancy rate was low in participants aged ≥ 35 with cyst ≥ 3cm and no significant difference was found between smaller vs. larger cyst groups. Conclusion: Endometrial cyst size does not affect the reproductive outcome in women after laparoscopic cystectomy; however, the age of participants and preoperative ovarian reserve are significant factors regarding reproductive function. Thus, preoperative ovarian reserve should be considered before surgery, especially in women aged ≥35 years.
Evaluation of Asthma Control Assessment in School-Age Asthmatic Children
Authors: Talha Safaa A.A.M , Magzoub Alhaj Omer Saeed , Elhag Abdelmoneim , Osman Haifaa Mohamed
Published: August 2022

Asthma is the most common chronic disease among children. Some 235 million people worldwide suffer from this non-communicable disease but effective medicines are available that can control it. Asthma is said to be under-estimated and under diagnosed in tropical countries including Sudan. Several tools are useful for detecting uncontrolled asthma in children; however, childhood asthma control test is a validated tool for assessing asthma control in pediatric asthma. A cross sectional study conducted over a period of six months (March 2016- September 2016) covering all school age asthmatic children attending the Asthma Clinic in Ahmed Gassim Children Specialized Hospital and Mohammed Elamin Hamid Pediatric Hospital during the period of study. The aim of this study is to assess asthma control in school age asthmatic children at Khartoum using childhood asthma control test (C- ACT) and peak flow meter (PEFR) and to detect associated factors with impaired asthma control. Result: A total of (84) asthmatics children most of them on prophylactic medications, according to ACT were found to be controlled 35 (41.7%), partially controlled 26 (22.2%) and uncontrolled 27 (32.1%). The main triggers as in other countries are infections, environmental factors and exercise. Conclusion: In this study, we realized that none of the children of study group underwent any PEFR measurement in their asthma follow up and none of them has been assessed with ACT before. There was a high percentage of partially controlled and uncontrolled asthma in the selected group.
Unavoidable Caesarean Myomectomy Due to Multiple Anterior Uterine Fibroids: A Case Report
Authors: IJ Onyekpa , BU Odugu , C Nevo , LN Onah , PK Enyinna , CN Ofonere , M Ezenweze , TC Ugwuanyi , CS Onyekpa
Published: August 2022

Background: Caesarean myomectomy is still a controversial issue in current obstetric practice due to the fear of uncontrollable haemorrhage. However, it may become very necessary occasionally with increased prevalence of fibroids among our pregnant mothers. Case Report: We report a case of Mrs UC, a 30-year-old primigravid woman who booked for antenatal care at 16 weeks gestational age following a 3-year history of infertility. The pregnancy was complicated with abdominal pain from red degeneration of uterine fibroid and was managed with pentazocine in the 2nd trimester. She presented in labour at 39 weeks and 4 days but labour was prolonged for 8 hours, having adequate contractions without any significant improvement in both descent and cervical dilatation. She subsequently had an emergency caesarean myomectomy with an outcome of a live female neonate that weighed 3.1kg with good Apgar scores and 2 pieces of uterine myoma that weighed 1.1kg. The post-operative and puerperal periods were uneventful. Conclusion: Caesarean myomectomy, a controversial obstetric procedure, can be indicated when the location and size of the fibroid mass makes caesarean delivery only very challenging and difficult.
Sazonalidade no nicho trófico da abelha-sem-ferrão Frieseomelitta meadewaldoi (Cockerell, 1915) (Hymenoptera, Apidae)
Authors: Batista Rondinelle Oliveira , Lima Luciene Cristina Lima e , Santos Francisco de Assis Ribeiro dos
Published: August 2022

Amostras de pólen de Frieseomelitta meadewaldoi foram analisadas para determinação das plantas utilizadas e respectivas frequências de ocorrência e diversidade, e assim testar se há correlação entre a diversidade de recursos com a temperatura ou a pluviosidade. Na estação chuvosa, F. meadewaldoi explorou 27 fontes florais, com maior riqueza de tipos polínicos de Fabaceae e Myrtaceae. Na estação seca, foram registrados 34 tipos polínicas, com maior riqueza associada a Fabaceae, Rubiaceae, Anacardiaceae e Myrtaceae. Fontes de recursos florais importantes e eventos de especialização temporária ocorreram em ambas as estações, com destaque para Coutobea, Eucalyptus, Ligaria teretiflora, Mimosa pudica, Mollugo verticillata, Myrcia, Richardia grandiflora e Tapirira guianensis. Não houve correlação entre diversidade de recursos polínicos e a temperatura ou pluviosidade, pois depende da disponibilidade de fontes de recursos florais. Assim, essa diversidade não diferiu entre os meses ou estações, pois o forrageio de F. meadewaldoi é semelhante ao longo do ano.
Development of a multiplex qPCR for the quantification of three protozoan parasites of the eastern oyster Crassostrea virginica
Authors: Piesz JL , Scro AK , Corbett R , Markey Lundgren K , Smolowitz R , Gomez-Chiarri M
Published: August 2022

A multiplex quantitative PCR (qPCR) assay for the simultaneous detection of 3 eastern oyster Crassostrea virginica parasites, Perkinsus marinus, Haplosporidium nelsoni, and H. costale, was developed using 3 different fluorescently labeled hydrolysis probes. The primers and probe from a previously validated singleplex qPCR for P. marinus detection were combined with newly designed primers and probes specific for H. nelsoni and H. costale. The functionality of the multiplex assay was demonstrated on 2 different platforms by the linear relationship of the standard curves and similar cycle threshold (CT) values between parasites. Efficiency of the multiplex qPCR assay on the Roche and BioRad platforms ranged between 93 and 101%. The sensitivity of detection ranged between 10 and 100 copies of plasmid DNA for P. marinus and Haplosporidium spp., respectively. The concordance between the Roche and BioRad platforms in the identification of the parasites P. marinus, H. nelsoni, and H. costale was 91, 97, and 97%, respectively, with a 10-fold increase in the sensitivity of detection of Haplosporidium spp. on the BioRad thermocycler. The concordance between multiplex qPCR and histology for P. marinus, H. nelsoni, and H. costale was 54, 57, and 87%, respectively. Discordances between detection methods were largely related to localized or low levels of infections in oyster tissues, and qPCR was the more sensitive diagnostic. The multiplex qPCR developed here is a sensitive diagnostic tool for the quantification and surveillance of single and mixed infections in the eastern oyster.
Dynamic spatiotemporal acoustic occurrence of North Atlantic right whales in the offshore Rhode Island and Massachusetts Wind Energy Areas
Authors: Estabrook BJ , Tielens JT , Rahaman A , Ponirakis DW , Clark CW , Rice AN
Published: August 2022

As development of offshore wind energy areas (WEAs) progresses along the US Atlantic coast, so will the spatiotemporal overlap and potential space-use conflict with vulnerable or protected wildlife, including Critically Endangered North Atlantic right whales (NARWs). Assessments of potential impacts from construction and operational activities on NARWs are dependent on the spatial, temporal, and acoustic overlaps between those activities and the occurrence of NARWs. Additionally, baseline distribution data of NARWs and data-driven policies are crucial to guide management decisions that minimize risk. The Massachusetts (MA) and Rhode Island-Massachusetts (RI-MA) Offshore WEAs currently comprise some of the largest lease areas and the first industry-scale offshore WEAs in the USA. Continuous passive acoustic data from 2011 through 2015 reveal highly variable seasonal, diel, and spatial NARW occurrence patterns within and near the MA and RI-MA WEAs. Under low (5th percentile) and median (50th percentile) noise conditions in the NARW communication frequency band (upcalls 71-224 Hz), we estimated detection ranges of 22 km (14 inter-quartile ranges [IQR]) and 8 km (5 IQR), respectively. Results underscore the influences of existing noise conditions on NARW communication and detectability within the MA and RI-MA WEAs. These dynamic NARW spatial and temporal occurrence data provide empirical support to enhance monitoring and mitigation strategies for minimizing risk to NARWs during periods of construction and identify time periods when heightened seasonal monitoring throughout the year during operations may be warranted.
Factors related to health-related quality of life in patients with acute coronary syndrome in West Java, Indonesia: A correlational study
Authors: Imam Haerul , Jitpanya Chanokporn
Published: August 2022

Background: Although acute coronary syndrome impacts patients’ health-related quality of life, a dearth of studies explore this issue in Indonesia. Thus, understanding factors associated with health-related quality of life among patients with acute coronary syndrome is a necessity.
Objective: This study aimed to examine the relationships between age, pain, dyspnea, functional status, self-efficacy, social support, and health-related quality of life in patients with acute coronary syndrome in West Java, Indonesia.
Methods: This study employed a descriptive correlational study involving 186 patients with acute coronary syndrome purposively selected in the outpatient clinics of the top referral public hospital. Data were collected in 2020 using validated instruments: Rose Questionnaire for Angina (RQA), Rose Dyspnea Scale (RDS), Seattle Angina Questionnaire (SAQ), General Self-efficacy Scale (GSE), ENRICHD Social Support Instrument (ESSI), and MacNew Health-Related Quality of Life. Data were analyzed using descriptive statistics and Spearman-rank correlation.
Results: Overall, the health-related quality of life in patients with acute coronary syndrome was high (Mean = 4.97, SD = 0.92), including in its subscales: emotional (Mean = 4.94, SD = 0.88), physical (Mean = 5.07, SD = 1.12), and social (Mean = 5.05, SD = 1.55) subscales. Significant factors related to health-related quality of life were pain (r = 0.296, p <0.001), functional status (r = 0.601, p <0.001), dyspnea (r = -0.438, p<0.001), and self-efficacy (r = 0.299, p <0.001). Meanwhile, age and social support had no significant relationships with health-related quality of life (p = 0.270, p = 0.059). Interestingly, social support was significantly correlated with the emotional subscale of health-related quality of life (r = 0.156, p = 0.034).
Conclusion: Functional status, pain, and self-efficacy were positively correlated with health-related quality of life, while dyspnea had a negative association. This finding serves as basic information for nurses and other healthcare professionals to consider the related factors identified in this study to improve nursing interventions in order to increase health-related quality of life among patients with acute coronary syndrome.