bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of BCR-ABL1 quantification in peripheral blood and bone marrow using an International Scale-standardized assay for assessment of deep molecular response in chronic myeloid leukemia
Authors: Greiner Georg , Ratzinger Franz , Gurbisz Michael , Witzeneder Nadine , Taghizadeh Hossein , Mustafa Sebastian G.K. , Mitterbauer-Hohendanner Gerlinde , Esterbauer Harald , Mannhalter Christine , Sperr Wolfgang R. , Valent Peter , Hoermann Gregor
Published: February 2020

Background

Monitoring of molecular response (MR) using quantitative polymerase chain reaction (PCR) for BCR-ABL1 is a pivotal tool for guiding tyrosine kinase inhibitor therapy and the long-term follow-up of patients with chronic myeloid leukemia (CML). Results of MR monitoring are standardized according to the International Scale (IS), and specific time-dependent molecular milestones for definition of optimal response and treatment failure have been included in treatment recommendations. The common practice to use peripheral blood (PB) instead of bone marrow (BM) aspirate to monitor the MR monitoring in CML has been questioned. Some studies described differences between BCR-ABL1 levels in paired PB and BM specimens.

Methods

We examined 631 paired PB and BM samples from 283 CML patients in a retrospective single-center study using an IS normalized quantitative reverse transcription (qRT)-PCR assay for quantification of BCR-ABL1
IS.

Results

A good overall concordance of BCR-ABL1
IS results was found, a systematic tendency towards higher BCR-ABL1
IS levels in PB was observed in samples of CML patients in a major MR. This difference was most pronounced in patients treated with imatinib for at least 1 year. Importantly, the difference resulted in a significantly lower rate of deep MR when BCR-ABL1
IS was assessed in the PB compared to BM aspirates.

Conclusions

In summary, our data suggest that the classification of deep MR in patients with CML is more stringent in PB than in BM. Our study supports the current practice to primarily use PB for long-term molecular follow-up monitoring in CML.
Combined Envelope Scaling with Modified SLM Method for PAPR Reduction in OFDM-Based VLC Systems
Authors: Touhami Ridha , Slimani Djamal , Abdulkafi Ayad Atiyah , Hussein Yaseein Soubhi , Alias Mohamad Yusoff
Published: February 2020

Orthogonal frequency-division multiplexing technique (OFDM) has been adopted widely as a modulation technique for radio frequency (RF) and optical communication systems such as visible-light communication (VLC) due to its high spectral efficiency and low-complexity implementation. VLC-OFDM is recommended in 5 G mobile communication. However, VLC-OFDM suffer from the high peak to-average power ratio (PAPR). In this paper, a modified selective mapping (MSLM) method is applied to the proposed system followed by a new envelope scaling process for further reductions in PAPR of VLC-OFDM system. Simulation results show that the proposed method reduces the PAPR by about 6.8 and 1.7 dB comparing with the original signal and the traditional SLM with a number of rotation vector U = 8, respectively.
Vertebrate prey composition analysis of the Pallas’s cat (Otocolobus manul) in the Gongga Mountain Nature Reserve, based on fecal DNA
Authors: Zhao Dong , Yang Chuangming , Ma Jinnan , Zhang Xiuyue , Ran Jianghong
Published: February 2020

Diet analysis is essential to fully understanding the biology of a species and its function within the ecosystem, and is also key in identifying food web interactions and the population dynamics of predators and prey. There is currently little information on the diet of small to mid-sized carnivores due to their elusive behavior. We used a DNA-based method to analyze the vertebrate prey of the Pallas’s cat (Otocolobus manul) in the Gongga Mountain Nature Reserve of southwestern China, a global biodiversity hotspot region. We confirmed 14 scat samples containing the Pallas’s cat DNA from 100 small carnivore scats collected at altitudes between 3200 and 4900 m, and then performed polymerase chain reaction (PCR) amplifications using primers targeting the vertebrate mitochondrial 12S rRNA gene with a blocking oligonucleotide specific to the predator sequence. We identified a total of 18 prey taxa, including nine mammals, eight birds and one fish. Our results show that pikas (in 79% of the scats) and birds (in 50% of the scats) are the predominant prey consumed by the Pallas’s cat in our investigation area. The most important finding in our study is that Cypriniformes species were found in the Pallas’s cat’s diet, exhibiting dietary diversification consistent with the accessible fauna of the surrounding environment. In order to increase the detectability of both typical and rare vertebrate prey items, we constructed a blocking primer to inhibit the amplification of the Pallas’s cat DNA.
Assessing the habitat use, suitability and activity pattern of the rusty-spotted cat Prionailurus rubiginosus in Kanha Tiger Reserve, India
Authors: Bora Jayanta Kumar , Awasthi Neha , Kumar Ujjwal , Goswami Shravana , Pradhan Anup , Prasad Ashish , Laha Deb Ranjan , Shukla Rakesh , Shukla Sanjay Kumar , Qureshi Qamar , Jhala Yadvendradev V.
Published: February 2020

The rusty-spotted cat Prionailurus rubiginosus is the smallest wildcat in the world, endemic to India, Nepal and Sri Lanka. Although new occurrence records have recently been reported from different geographic localities in India and Nepal, there is still a lack of information on its biology and habitat use that are required for its conservation planning. Herein, we report results from systematic, long-term (2014–2018) camera trapping in Kanha Tiger Reserve, India, to evaluate the habitat use, suitability and activity pattern of the rusty-spotted cat and model its local distribution with habitat and anthropogenic covariates. Thick canopied forest and rugged terrain were found to be extensively used and preferred by the rusty-spotted cat. It was also recorded in the multiple-use buffer zone forests in close proximity to agriculture. The species is nocturnal and its activity seems to coincide with its major prey. The guiding philosophy of tiger reserves in India is to use the tiger as an umbrella species for biodiversity conservation, and often these reserves are intensively managed to enhance tiger and prey populations. This approach, however, may not cater to the requirements of other less charismatic sympatric species, and those of the rusty-spotted cat also need to be considered for its continued survival.
Una aproximación al estilo comunicativo de cercanía interpersonal del español a partir de la teoría de la Metalengua Semántica Natural
Authors: Fernández Susana S. , Goddard Cliff
Published: February 2020

El presente artículo discute un estilo comunicativo típico de muchos hispanohablantes, que a menudo ha sido caracterizado en la literatura sobre pragmática y comunicación intercultural como de cercanía interpersonal y de confianza. El punto de partida teórico y metodológico es la teoría de la Metalengua Semántica Natural (NSM, por sus siglas en inglés), que propone el uso de un minivocabulario de conceptos básicos para explicar otros más complejos. En este caso, presentamos descripciones (que en la teoría se denominanguiones culturales) de distintos aspectos de este estilo comunicativo de cercanía y de palabras claves culturales y rasgos gramaticales relacionados con este modo de comunicar al que, consciente o inconscientemente, adhieren muchos hispanohablantes. Nos basamos en trabajos ya realizados por otros autores dentro de la NSM y proponemos también nuevas descripciones.
The Effect of Body Composition on Cycling Power During an Incremental Test in Young Athletes
Authors: Schomöller Anne , Schugardt Monique , Kotsch Peggy , Mayer Frank
Published: February 2020

Schomöller, A, Schugardt, M, Kotsch, P, and Mayer, F. The effect of body composition on cycling power during an incremental test in young athletes. J Strength Cond Res 35(11): 3225–3231, 2021—As body composition (BC) is a modifiable factor influencing sports performance, it is of interest for athletes and coaches to optimize BC to fulfill the specific physical demands of one sport discipline. The purpose of this study is to test the impact of body fat (BF) and fat-free mass (FFM) on aerobic performance in young athletes. Body composition parameters were evaluated among gender and age groups of young athletes undergoing their mandatory health examination. The maximal power (in Watts per kilogram body mass) of a stepwise incremental ergometer test was compared between 6 BC types: high BF, high FFM, high BF and high FFM, normal BC values, low BF, and low FFM. With increasing age (11–13 vs. 14–16 years) BF decreased and FFM increased in both genders. Both BC parameters, as well as body mass, correlated moderately with performance output (r = 0.36–0.6). Subjects with high BF or high FFM or both had significantly lower ergometer test results compared with those with low BF and FFM in all age and gender groups (p < 0.05). The finding that high levels of BF and FFM are detrimental for cycle power output is important to consider in disciplines that demand high levels of aerobic and anaerobic performance.
Increased Resisted Sprinting Load Decreases Bilateral Asymmetry in Sprinting Kinetics Among Rugby Players
Authors: Mangine Gerald T. , McNabb Jacob A. , Feito Yuri , VanDusseldorp Trisha A. , Hester Garrett M.
Published: February 2020

Mangine, GT, McNabb, JA, Feito, Y, VanDusseldorp, TA, and Hester, GM. Increased resisted sprinting load decreases bilateral asymmetry in sprinting kinetics among rugby players. J Strength Cond Res 35(11): 3076–3083, 2021—To examine the effect of resistance on sprinting kinetics and their bilateral symmetry, 15 male collegiate rugby players completed 3 maximal, 40-m sprints (S1–S3) while tethered to a robotic resistance device. Minimal resistance (9.81 N) was used on S1 (familiarization) and S2, while S3 was loaded at 147.1 N. Peak and average (AVG) power (P), velocity (V), force (F), and rate of force development (RFD) were averaged within the first stride, the acceleration and peak velocity phases, as well as across the 40-m sprint. Bilateral percent differences were calculated from step values within each stride for each variable. Friedman's rank tests revealed differences (p ≤ 0.02) between sprint trials and phases for each variable. During both trials, most kinetic measures increased from the first stride through the peak velocity phase (p ≤ 0.036), although reductions in RFDPEAK (p ≤ 0.015) and RFDAVG (S3 only; p < 0.001) were observed within the peak velocity phase. Comparatively, sprinting velocity and average stride (length and duration) were less during S3, while all other measures were greater within each phase. Across the entire 40-m sprint, S3 reduced (p < 0.05) asymmetry for average stride length (−2.1 to −17.0%), VPEAK (−0.8 to −4.9%), VAVG (−2.3 to −6.0%), FPEAK (−5.6 to −8.7%), FAVG (−3.4 to −7.1%), RFDPEAK (−4.3 to −36.7%), PPEAK (−5.9 to −12.4%), and PAVG (−5.4 to −9.8%). Applying sprinting resistance may be a tool for reducing acute bilateral asymmetries in sprinting kinetic measures.
Anodal Transcranial Direct Current Stimulation Increases Muscular Strength and Reduces Pain Perception in Women With Patellofemoral Pain
Authors: Rodrigues Guilherme Moraes , Paixão Alexandre , Arruda Thiago , de Oliveira Bruno Ribeiro Ramalho , Maranhão Neto Geraldo Albuquerque , Marques Neto Silvio Rodrigues , Lattari Eduardo , Machado Sergio
Published: February 2020

Rodrigues, GM, Paixão, A, Arruda, T, de Oliveira, BRR, Maranhão Neto, GA, Marques Neto, SR, Lattari, E, and Machado, S. Anodal transcranial direct current stimulation increases muscular strength and reduces pain perception in women with patellofemoral pain. J Strength Cond Res 36(2): 371–378, 2022—The purpose of this study is to investigate the effects of anodic transcranial direct current stimulation applied to motor cortex combined with open kinetic chain exercises on muscular strength and pain perception in women with patellofemoral pain (PFP). Twenty-eight women aged between 18 and 30 years with PFP were selected. Subjects were randomized in 2 groups, anodic stimulus plus resistance training (n = 14; anodic transcranial direct current stimulation [a-tDCS] + RT) or placebo stimulus plus resistance training (n = 14; Sham + RT) and attended the laboratory for 12 experimental sessions, 48–72 hours apart from each other. The RT protocol consisted of 3 sets of 12 repetitions of the knee extension exercise at 60% of 10 maximal repetition (10RM) with a 1-minute interval between sets. In the a-tDCS + RT group, a 2-mA current was applied for 20 minutes over the motor cortex before the RT protocol in each session. In the Sham + RT group, the stimulus was interrupted after 30 seconds. Preintervention, fourth session, eighth session, and postintervention, load was assessed through a 10RM test. The pain perception was assessed through Clarke sign maneuver (CSM) and measured through a visual analogue scale for pain. The a-tDCS + RT group showed greater 10RM load than Sham + RT group at eighth session (p < 0.05) and postintervention (p < 0.05). In a-tDCS + RT group, pain perception reduced in the postintervention compared with preintervention (p < 0.05). The intervention a-tDCS + RT was able to improve muscular strength in women with PFP. In addition, pain perception only decreased postintervention in the a-tDCS + RT group. This combined intervention can be used by coaches in rehabilitation programs aiming to treat PFP through medium-term strength gains.
Complex and Contrast Training: Does Strength and Power Training Sequence Affect Performance-Based Adaptations in Team Sports? A Systematic Review and Meta-analysis
Authors: Cormier Patrick , Freitas Tomás T. , Rubio-Arias Jacobo Á. , Alcaraz Pedro E.
Published: February 2020

Cormier, P, Freitas, TT, Rubio-Arias, JÁ, and Alcaraz, PE. Complex and contrast training: Does strength and power training sequence affect performance-based adaptations in team sports? A systematic review and meta-analysis. J Strength Cond Res 34(5): 1461–1479, 2020—The aims of this meta-analysis were to examine the effects of 2 different strength and power training sequences (complex: CPX; and contrast: CNT, training) on performance-based adaptations in team sports {lower-body strength (1 repetition maximum [1RM]), vertical jump (VJ), sprinting, and change of direction (COD) ability}, as well as identify factors potentially affecting said adaptations (i.e., athlete level, type of sport, intensity, and duration). CPX is the combination training that alternates biomechanically similar high load weight training exercises with lighter load power exercises, set for set (e.g., squats followed by countermovement jumps). CNT is the combination training where all high load strength exercises are performed at the beginning of the session and all lighter load power exercises at the end. After an electronic database search (PubMed, SPORTDiscus, and WoS), a total of 27 articles were included in the meta-analysis. The effects on outcomes were expressed as standardized mean differences (SMDs). Baseline to postintervention overall results for the studied variables: (a) 1RM: large effects for CPX (SMD = 2.01, 95% confidence interval [CI] 1.18–2.84) and CNT (SMD = 1.29, 95% CI 0.61–1.98); (b) VJ: large effects for CPX (SMD = 0.88, 95% CI 0.42–1.34) and medium effects for CNT (SMD = 0.55, 95% CI 0.29–0.81); (c) sprint: large effects for CPX (SMD = −0.94, 95% CI −1.33 to −0.54) and small effects for CNT (SMD = −0.27, 95% CI −0.92 to 0.39); and (d) COD: large effects for CPX (SMD = −1.17, 95% CI −1.43 to −0.90) and medium effects for CNT (SMD = −0.68, 95% CI −1.20 to −0.15). Regarding the studies that contained a control group: (a) 1RM: large effects for CPX (SMD = 1.61, 95% CI 1.12–2.10) and CNT (SMD = 1.38, 95% CI 0.30–2.46); (b) VJ: large effects for CPX (SMD = 0.85, 95% CI 0.45–1.25) and medium for CNT (SMD = 0.50, 95% CI 0.19–0.81); (c) sprint: medium effects for CPX (SMD = −0.69, 95% CI −1.02 to −0.36) and CNT (SMD = −0.51, 95% CI −0.90 to −0.11); and (d) COD: large effects for CPX (SMD = −0.83, 95% CI −1.08 to −0.59), and there were no control groups for CNT. In conclusion, both training interventions may lead to positive performance-based adaptations in team-sports with CPX interventions potentially leading to slightly greater effects.
Setting Kinematic Parameters That Explain Youth Basketball Behavior: Influence of Relative Age Effect According to Playing Position
Authors: Pino-Ortega José , Gómez-Carmona Carlos D. , Nakamura Fabio Y. , Rojas-Valverde Daniel
Published: February 2020

Pino-Ortega, J, Gómez-Carmona, CD, Nakamura, FY, Rojas-Valverde, D, and Effect, RA. Setting kinematic parameters that explain youth basketball behavior: Influence of relative age effect according to playing position. J Strength Cond Res 36(3): 820–826, 2022—The aims of the present study were to (a) set kinematic behavior parameters during official matches by principal component analysis (PCA), (b) examine the distribution of birth dates in competitive basketball, differentiating by playing position, and (c) analyze the relative age effect (RAE) on kinematic performance according to playing position. A total of 94 young elite athletes participated in an official U18 Euroleague tournament (8 clubs, 4 days, 3 games). Kinematic motion variables were measured using an inertial device worn by all players during matches. A total of 252 variables were measured, a PCA was performed to select them for final analysis and 3 principal components and 6 variables were extracted (maximum acceleration [MAcc], average acceleration [PAcc], landing 8–100 G [Ldg 8–100 g·min−1], relative distance [RD], jump average take off [MJumpsTO], and jump average landing [MJumpsLdg]). These variables explained 66.3% of total variance. Differences were found in RD (p = 0.04;

= 0.02), PAcc (p = 0.04;

= 0.02), MAcc (p < 0.01;

= 0.03), and Ldg 8–100 g·min−1 (p = 0.02;

= 0.02) because of RAE. There were differences by playing position in Ldg 8–100 g·min−1 (guards, p = 0.04;

= 0.03), MAcc (forwards, p < 0.01;

= 0.07; centers, p < 0.01;

= 0.44), PAcc (centers, p < 0.01;

= 0.34) and in MJumpsLdg (centers, p = 0.03;

= 0.13). Results suggested that RAE does have an impact on kinematic variables, and is affected by playing position in variables such as MAcc, PAcc, MJumpsLdg, and Ldg 8–100 g·min−1. The extracted variables are well-known intensity indicators and fundamental performance variables. This evidence should be taken into account by sport scientists and coaches to develop individualized training programs and match tactics.
Acute Effects of Different Warm-up Protocols on Sports Performance in Elite Male Collegiate Handball Players
Authors: Chen Che-Hsiu , Chang Chien-KM , Tseng Wei-Chin , Chiu Chih-Hui , Dai Xiang , Ye Xin
Published: February 2020

Chen, CH, Chang, CK, Tseng, WC, Chiu, CH, Dai, X, and Ye, X. Acute effects of different warm-up protocols on sports performance in elite male collegiate handball players. J Strength Cond Res 36(8): 2262–2267, 2022—This study aimed to examine the effects of 3 different warm-up protocols on subsequent sports performance in elite male collegiate handball players. Fifteen handball players (19.0 ± 2.4 years) completed 3 separated randomly sequenced experimental visits. During each visit, they started with different warm-up protocols (traditional warm-up [TRAD] vs. warm-up with core stability exercises [CORE] vs. warm-up with elastic band exercises [ELAS]) and completed with a series of randomly ordered sport-specific performance testing measurements: 30-m sprint, countermovement jump, medicine ball overhead forward throw, and standing and jump handball throw tests. Both CORE and ELAS protocols induced statistically significant differences (p < 0.05) on overall sports performance (sprint time, jump height, medicine ball throwing peak velocity and power, and handball throwing velocities), as compared to the TRAD. In addition, the ELAS protocol imposed small-to-medium effects (effect size range: 0.45–0.82), enhancing handball throwing velocity and medicine ball throwing performance comparing with the CORE. Sport-specific warm-up protocols that contain core stability or elastic band–based exercises likely induced subsequent performance enhancements (sprint, jump, and throw) in elite male collegiate handball players when compared with TRAD. Furthermore, including elastic band exercises in the warm-up protocol even induced superior upper-body performance enhancement (explosive power and handball throwing velocity) than other protocols. Therefore, preconditioning warm-up activities using elastic band–based exercises can be integrated into a traditional sport-specific warm-up protocol for elite collegiate handball players before competition or training.
A Systematic Review and Meta-analysis of the Effect of Multi-ingredient Preworkout Supplementation on Strength, Exercise Volume, and Anaerobic Capacity in Healthy Resistance-Trained Individuals
Authors: Bobos Pavlos , Nazari Goris , Ziebart Christina , MacDermid Joy C. , Kostopoulos Nikolaos
Published: February 2020

This study assessed the effectiveness of multi-ingredient preworkout supplements (MIPSs) when compared with placebo on strength, power, exercise volume, and anaerobic capacity in healthy resistance-trained individuals. Twenty-two (n = 22) studies and 458 participants were included. Quality of outcomes was rated as low and was downgraded mostly because of imprecision and high risk of bias. Optimal forms and strategies on MIPS consumption and use has not yet been rigorously examined. Although improvements were noted for lower body strength (repetitions) and upper body power (Watts), most results were inconclusive, and the results showing improvements were presented in low-quality studies (see Video Supplemental Digital Content 1, http://links.lww.com/SCJ/A276).
Effects of Efferent Activity on Hair Bundle Mechanics
Authors: Lin Chia-Hsi Jessica , Bozovic Dolores
Published: February 2020

Hair cells in both the auditory and vestibular systems receive efferent innervation. A number of prior studies have indicated that efferent regulation serves to diminish the overall sensitivity of the auditory system. The efferent pathway is believed to affect the sensitivity and frequency selectivity of the hair cell by modulating its membrane potential. However, its effect on the mechanical response of the hair cell has not been established. We explored how stimulation of the efferent neurons affects the mechanical responsiveness of an individual hair bundle. We tested this effect onin vitropreparations of hair cells in the sacculi of American bullfrogs of both genders. Efferent stimulation routinely resulted in an immediate increase of the frequency of hair bundle spontaneous oscillations for the duration of the stimulus. Enlarging the stimulus amplitude and pulse length, or conversely, decreasing the interpulse interval led to oscillation suppression. Additionally, we tested the effects of efference on the hair bundle response to mechanical stimulation. The receptive field maps of hair cells undergoing efferent actuation demonstrated an overall desensitization with respect to those of unstimulated cells.

SIGNIFICANCE STATEMENTThe efferent system is an important aide for the performance of the auditory system. It has been seen to contribute to sound detection and localization, ototoxicity prevention, and speech comprehension. Although measurements have demonstrated that efference suppresses basilar membrane movement, there is still much unknown about how efferent activity affects hearing mechanics. Here, we explore the mechanical basis for the efferent system's capabilities at the level of the hair bundle. We present optical recordings, receptive field maps, and sensitivity curves that show a hair bundle is desensitized by efferent stimulation. This supports the hypothesis that efferent regulation may be a biological control parameter for tuning the hair bundle's mechanical sensitivity.
Agency, Authenticity, and Parody in Palestinian Hip Hop
Authors: Brzobohaty Avery
Published: February 2020

Throughout the discourse surrounding the Israel-Palestine conflict many methods have emerged to examine the ways in which artists engage with the issues through popular culture. As hip hop spread globally, its universal themes and ability to constitute community led to the use of rap as a vehicle for political commentary. This paper explores how the Palestinian hip hop group DAM provides a commentary on the experiences of Palestinian-Israelis through carnivalesque methods to create shocking juxtapositions. Using an inter-textual method, we can see that humor allows DAM to freely speak “their truth,” defusing tensions and providing a new perspective on the conflict, opening dialogue, and regaining control over a painful history. This case study raises questions of authenticity, agency, and parody in hip hop. The genre blurs the threshold of true and false and allows artists to present a conventional hip hop persona, giving them the freedom to safely comment on social issues. Humor allows for further political commentary under the façade of a joke. By parodying painful racial, gender, and class stereotypes, artists reclaim their identity and further subvert prejudices against them. This case study challenges the notion of what protest music looks like, and how it functions to promote change.
Pediatricians’ Experiences With and Perceptions of the Vaccines for Children Program
Authors: O’Leary Sean T. , Allison Mandy A. , Vogt Tara , Hurley Laura P. , Crane Lori A. , Brtnikova Michaela , McBurney Erin , Beaty Brenda L. , Crawford Nathan , Lindley Megan C. , Stokley Shannon K. , Kempe Allison
Published: February 2020

BACKGROUND AND OBJECTIVES:

The Vaccines for Children Program (VFC) provides vaccines for children who may not otherwise be vaccinated because of financial barriers. Pediatrician participation is crucial to the VFC’s ongoing success. Our objectives were to assess, among a national sample of pediatricians, (1) VFC program participation, (2) perceived burden versus benefit of participation, and (3) knowledge and perception of a time-limited increased payment for VFC vaccine administration under the Patient Protection and Affordable Care Act.

METHODS:

An electronic and mail survey was conducted from June 2017 to September 2017.

RESULTS:

Response rate was 79% (372 of 471); 86% of pediatricians reported currently participating in the VFC; among those, 85% reported never having considered stopping, 10% considered it but not seriously, and 5% seriously considered it. Among those who had considered no longer participating (n = 47), the most commonly reported reasons included difficulty meeting VFC record-keeping requirements (74%), concern about action by the VFC for noncompliance (61%), and unpredictable VFC vaccine supplies (59%). Participating pediatricians rated, on a scale from −5 (high burden) to +5 (high benefit), their overall perception of the VFC: 63% reported +4 or +5, 23% reported +1 to +3, 5% reported 0, and 9% reported −1 to −5. Of pediatricians, 39% reported awareness of temporary increased payment for VFC vaccine administration. Among those, 10% reported that their practice increased the proportion of Medicaid and/or VFC-eligible patients served on the basis of this change.

CONCLUSIONS:

For most pediatricians, perceived benefits of VFC participation far outweigh perceived burdens. To ensure the program’s ongoing success, it will be important to monitor factors influencing provider participation.
ВІЛЬНІ КОЛИВАННЯ ПІДПІРНИХ СТІНОК, ЩО СКЛАДАЮТЬСЯ З ПІДКРІПЛЕНИХ ОРТОТРОПНИХ ЦИЛІНДРИЧНИХ ОБОЛОНОК, КОНТАКТУЮЧИХ З НЕОДНОРІДНИМ В'ЯЗКОПРУЖНИМ ГРУНТОМ
Authors: Latifov F. S. , Ganiev D. S.
Published: February 2020

Досліджено одну з динамічних характеристик міцності – частоту власних коливань підпірної стінки, що складається з двох ортотропних циліндричних оболонок, контактуючих з неоднорідним в'язкопружним грунтом і посилених дискретно розподіленими кільцевими стрижнями. Використовуючи варіаційний принцип Гамільтона – -Остроградського для знаходження частот коливань підпірних стінок побудовано частотне рівняння, знайдені його корені і вивчен вплив фізичних та геометричних параметрів, що характеризують систему. В якості контактних умов прийнято урахування спільної роботи на лінії контакту двох циліндричних оболонок.
ВИБІР РАЦІОНАЛЬНИХ ПАРАМЕТРІВ ПІДКРІПЛЮЮЧИХ ЕЛЕМЕНТІВ ПРИ КОМП’ЮТЕРНОМУ МОДЕЛЮВАННІ ПОВЕДІНКИ ЦИЛІНДРИЧНОЇ ОБОЛОНКИ З ДВОМА ПРЯМОКУТНИМИ ОТВОРАМИ
Authors: Гарт Е. Л. , Терьохін Б. І.
Published: February 2020

Досліджено напружено-деформований стан тонкостінної циліндричної оболонки з двома прямокутними отворами та чотирма видами включень. На основі проведеного скінченно-елементного аналізу визначено вплив форми, розмірів та матеріалу включень на напружено-деформований стан оболонки в місцях локальних концентраторів напружень. Подано рекомендації щодо зниження концентрації напружень.
ТЕРМОМЕХАНІЧНЕ ДЕФОРМУВАННЯ ПОРОЖНИСТОГО КОМПОЗИТНОГО ЦИЛІНДРА ЗА РІЗНИХ ТИПІВ АРМУВАННЯ КОМПОЗИТУ
Authors: Клименко М. І. , Гребенюк С. М. , Богуславська А. М.
Published: February 2020

У роботі отримано розв’язок вісесиметричної задачі термопружності для порожнистого циліндра, що знаходиться під дією силового та температурного навантаження. Розрахунки проведено з урахуванням температурної залежності механічних характеристик композиту. Отримано розв’язки задачі для різних типів армування волокнами та об’ємного вмісту волокна в композиті. Проведено порівняння вісесиметричного деформування циліндра за наявності та відсутності впливу температурного поля.
MODELING OF BIOMECHANICAL SYSTEM ELEMENT STRUCTURE
Authors: Pogrebnoy O. V.
Published: February 2020

The element structure of a biomechanical system subjected an action of external force factors is studied. The radiocarpal joint of wrist is regarded as biomechanical system. The scaphoid bone is one element of the biomechanical system under investigation. The morphometrical analysis of cuts made in scaphoid frontal plane is fulfilled. The increase of bone tissue density from the cut centre to its periphery is revealed. The significant difference of bone tissue density in proximal and distal parts is determined too. The revealed tendencies allow us to develop the recommendations of construction design for scaphoid osteosynthesis.

 

biomechanical system, modeling, morphometry, radiocarpal joint, scaphoid, spongy bone tissue, fracture.
NUMERICAL SIMULATION OF SUBSONIC FLOW OVER A PROFILE
Authors: Alekseyenko S. V.
Published: February 2020

A methodology and software-methodical support for describing the processes of flow around a wing profile by a viscous compressible flow based on the Reynolds-averaged Navier – Stokes equations using the Spalart – Almaras turbulence model is developed. The effect of Mach number variation at constant Reynolds number on the profile performance coefficients is analyzed.
КОМБІНОВАНЕ КЕРУВАННЯ КОСМІЧНИМ СТУПЕНЕМ РАКЕТИ-НОСІЯ
Authors: Шептун Ю. Д.
Published: February 2020

The processes of working out the perturbations of the movement parameters of the LV stages are characterized by features that are not currently taken into account in the algorithms for zeroing perturbations by missile control systems. The article contains proposals on minimization of fuel consumption for zeroing the perturbations of rocket motion parameters.
THE MODEL OF A RADIO LINK "SPACE-TO-EARTH" WITH MORE INFORMATIVE FOR A LOW ORBIT SATELLITE
Authors: Savchenko Igor Dmitrovich , Kulabukhov Anatoly Mikhailovich , Masalskiy Viktor Alexandrovich , Tishchenko Aramais Viktorovich
Published: February 2020

A proposed the model of a radioline “space-to-Earth” with more informative for a low orbit university nanosatellite. The radioline is modeled on a antenna of the high-frequency S-band. At present time, the tasks of creating radiolines “space-to-Earth” in the conditions of limited energy of satellites with more informativeness (for telemetry radiolines and information radiolines) constantly require increasing their capabilities. Various options are being developed to implement such a solution, ranging from increasing the data transmission time due to repeaters and developing new encoding methods and increasing the bandwidth of radio lines. One solution is to use middle or high gain antennas.

The model of a radioline is designed on the basis of the high-frequency (S-band) antenna. The calculations were carried out according to the international format of the AMSAT-IARU-Link-Model program. The calculation of the proposed the model consists of three basic conditions: the greatest loss of energy of the radio signal in free space, equivalent to isotropic radiating power and quality factor of the receiving station. The proposed model is built on the basis of a phased antenna array with a gain of 12 dBi for transmit from nanosatellite, the gain of the receiving antenna is 35 dBi. The results showed the ability to transmit up to 50 images of the Earth's surface per day. The use of a phased array antenna and the transition to the S-band allowed with smaller dimensions to increase the antenna gain and the rate of information transmission in communication sessions.
PROSPECTS OF ANISOGRID LATTICE STRUCTURES USING IN ADAPTERS OF LAUNCH VEHICLE
Authors: Proroka Vladislav Arkadiyovych , Lypovskyi Vladimir Ivanovich
Published: February 2020

The efficiency of using anisogrid lattice structures in launch vehicle designs, in particular in payload adapters, is investigated. On a specific example of the design of the adapter, which is in operation, it is compared with an anisogrid adapter, which is made of different materials - composite, made by winding, and metal using additive technologies. The performance of the adapter was evaluated by the criterion of minimum mass, subject to the requirements of strength and stability. The initial geometric parameters of the anisogrid lattice structure were determined under the condition that the critical stresses are equal for the symmetric and asymmetric cases of stability loss for the structural orthotropic shell model. Calculations and comparisons were made for composite materials - fiberglass, carbon fiber, organoplastic and boraluminium, as well as metal - AMG6M, BT20. Checking the geometrical parameters calculated on the model of structural orthotropic shell showed that they do not meet the requirements of strength and stability. The choice of geometric parameters of a working adapter design is made by numerical experiment with finite element method. The geometry of the lattice structure of the adapter was parameterized to ensure the variability of two geometric dimensions of the cross section of the longitudinal rib and two geometric dimensions of the cross section of the upper frame. The numerical experiment was performed for the constructions made of carbon plastic and for metals AMG6M, BT20. The results of the calculations showed that the anisogrid lattice structures give a gain on the weight of the adapters, which is up to 50% compared to the designs in operation.
DEVELOPING AND CREATION OF GROUND TESTING SIMULATOR FOR ORIENTATION AND STABILIZATION SYSTEM OF POLYITAN NANOSATELLITES
Authors: Padun O. , Kovalenko Y. , Rassamakin B. , Ostapchuk V. , Pynchuk A.
Published: February 2020

The article under the heading "Developing and creation of ground testing simulator for orientation and stabilization system of PolyITAN nanosatellites" is devoted to the research of methods of developing of the specialized simulator for the nanosatellite orientation and stabilization system ground testing. This problem is showed on the example of simulator developed in the National Technical Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”. Ground testing of the orientation and stabilization system is critically important phase of the pre-flight preparation of the nanosatellite. In order to provide precise tests, the simulator described in this article was developed. Objective of the simulator is to create targeted magnetic field in assured volume, where flight of the nanosatellite is imitated, stabilization and orientation performances are tested. The introduction describes experience of the PolyITAN team in developing of nanosatellites, the tasks of the first two nanosatellites - PolyITAN-1 and PolyITAN-2 are revealed, the actuality of this research is highlighted. The main part reveals the order of development of the simulator for orientation and stabilization system ground testing in gradual and sector-wise way. First part shows construction decisions in the simulator’s configuration to ensure accomplishment of the simulator’s objective. Second part describes calculation of the number of turns and the diameter of the wire to provide required value of the modulus of the vector of magnetic field induction, which is created by the simulator. Next part is devoted to calculation of power required for power sources, increment of magnetic field induction as a function of the current increment is provided, what is very important for power source selection. Next part is a research of the uniformity sphere - working space of the simulator, which must provide enough volume for testing of the 3U nanosatellites of CubeSat format. Final part describes control system of the simulator.
SYNTHESIS OF AN ADAPTIVE AUTOMATIC SYSTEM OF AIRCRAFT CONTROLS WITH MULTIDIMENSIONAL PI-REGULATOR
Authors: Tishchenko Aramis Viktorovich , Kulabukhov Anatoly Mikhailovich , Masalskiy Victor Alexandrovich
Published: February 2020

The article presents the synthesis of a functional diagram of an adaptive automatic control system (ACS) for controlling an aircraft with an automatically reconfigurable multidimensional PI controller, which provides the minimum static and minimum mean square error of control with minimal energy consumption for the formation of the control exposure. The synthesis of ACS algorithms is performed as a result of solving the problem of conditionally minimizing the quadratic functional of the generalized work (taking into account restrictions on state variables and control actions given by differential equations of the control object (CO) and inequalities). The mathematical description of the multidimensional CO is carried out using the CO model in the state space, which automatically takes into account the mutual influence of individual control loops on each other. As the state variables of the aircraft, linear displacements, speeds and accelerations of the center of mass of the aircraft, and angular displacements, speeds and accelerations of the rotational movement of the aircraft relative to the center of mass are used. The matrix equation of dynamics of the aircraft is formed by a system of nonlinear differential equations of the first order of forces and moments of forces acting on the aircraft. To ensure the minimum static control error, integrators are included in the ACS (for each control action). The algorithm for the formation of control actions of the extended CO, providing the declared properties of the ACS, is obtained as a result of solving the problem of conditional minimization of the generalized work functional. The task of conditional minimization of a functional with constraints is performed by the maximum principle. The resulting two-point boundary value problem is transformed by the invariant immersion method into a Cauchy problem for optimal values of state variables. The evaluation of the characteristics of a specific adaptive ACS for the spacecraft is expected to be obtained as a result of further research by mathematical modeling.
Satanic Temple
Authors: Hedenborg White Manon , Gregorius Fredrik
Published: February 2020

This article explores the development and ideology of The Satanic Temple,against the background of current American politics. The Satanic Temple isa recent addition to the Satanic milieu, and is positioned here as a form of"rationalist" Satanism that draws on the figure of Satan as a symbol of rebellion.The discussion follows the emergence of The Satanic Temple and itsintroduction to the mainstream media around 2012, the influences of esoteric,feminist, and secularist ideas on the group, and its present manifestationas a politically engaged "occulture."
Effect of Perceptual Exercise Program on Basic Motor Skills in a Child with Intellectual Disability: Single Subject Research Design
Authors: Song Sang-Hyup
Published: February 2020

OBJECTIVES The purpose of this study was to identify the effect of perceptual exercise program on basic motor skills in a child with intellectual disability.METHODS One child with intellectual disability was participated in this study. Perceptual exercise program was performed 60 minutes per session, twice a week for 32 weeks. To evaluate the basic motor skills of the subject pre and post the exercise, subject was measured in six areas of operational skills including throwing, catching, kicking, hitting, bouncing, and rolling; two areas of movement skills including balance beam, walking backward; and two areas of stabilization skills including standing with one leg and escaping.RESULTS The subject who participated in this study gained 60% throwing, 60% catching, 80% kicking, 60% hitting, 80% bouncing, and 60% rolling was increased respectively in the operational skills and 80% balance beam, 100% walking backward in the movement skills, and 80% standing with one leg, 100% escaping in the stabilization skills.CONCLUSIONS Those results show that perceptual exercise program was positive influence on operational skills, movement skills and stabilization skills in a child with intellectual disability.
Alcohol and other drug use, and mental distress in the women’s universe
Authors: Silva Júnior Fernando José Guedes da , Monteiro Claudete Ferreira de Souza
Published: February 2020

ABSTRACT Objective: to analyze the relationship between alcohol and other drug use, and mental distress among women. Method: an analytical cross-sectional study conducted with 369 women in Piauí State. Alcohol Use Disorders Identification Test, Non-Student Drugs Use Questionnaire and Self-Reporting Questionnaire and inferential statistics were used. Results: women with heavy alcohol consumption (zone IV - possible dependence) are 2.1 times more likely to have mental distress. Consuming tobacco increases the odds of distress 3.5%, tranquilizers 2.6 times and cannabis 4.5 times. There is a statistically significant and positive correlation between the Alcohol Use Disorders Identification Test score and the Self-Reporting Questionnaire (p = 0.000; r = 0.250). Conclusion: alcohol, tobacco, tranquilizers and cannabis use is associated with mental distress. The more intense the alcohol consumption, the more intense the mental distress. Therefore, it is necessary to track alcohol and other drug consumption, and mental distress in the routine care of women.
Genetic polymorphism among natural populations of Anacardium humile A. ST-HIL
Authors: Santos Silvia Correa , Carvalho Raquel dos Santos , Davide Livia Maria Chamma
Published: February 2020

Abstract The genus Anacardium presents nine species, of these, three have sub-bush size, common in the Cerrado of the Center-West of Brazil. The objective of this work was to evaluate the genetic variability of the species, collected in eleven provenances, using RAPD markers. Genomic DNA from 122 accessions was extracted and amplified with 25 decamer primers. The results indicated polymorphism, ranging from 77.71% to 96.18%. The distribution of genetic diversity among and within populations shows that 27.14% of the variability is found between populations and 37.44% within the populations, suggesting the existence of genetic variability that may be related to the reproductive strategies adopted by the species throughout its evolution. The index of variation within the provenances (93.36%) was higher than the index found among populations (6.64%). Molecular analysis indicated that there is genetic divergence between and within the studied populations of Anacardium humile A. St. - Hill. The origin of Itajá-GO presented the highest genetic diversity, presenting the highest values of genetic diversity index, phenotypic diversity and higher percentage of polymorphic loci.
Changes in leaf nutrient content and quality of pear fruits by biofertilizer application in northeastern Italy
Authors: Perazzoli Barbara Elen , Pauletti Volnei , Quartieri Maurizio , Toselli Moreno , Gotz Lenir Fátima
Published: February 2020

Abstract The aim of this study was to verify the influence of biofertilizer application resulting from energy production from corn biomass on nutrient uptake by pear plants during the growing cycle, and on fruit quality. The experiment was carried out on a Siltic Haplic Calcisol in the Italian province of Ferrara, in a medium-density Abbé Fétel commercial orchard. Treatments consisted of control (no application) and biofertilizer (30 m3 ha-1 biofertilizer application on the row), with four replicates. The following variables were evaluated: mineral N, microbial biomass and respiration in soil; nutrient content in leaves; and fruit quality. Biofertilizer application increased soil mineral N availability; soil microbial biomass and respiration, but the content of this nutrient did not increase in leaves. Leaf nutrient concentration varied during growth season and biofertilizer application increased potassium, phosphorus and zinc concentration in mature leaves and reduced leaf magnesium and manganese concentration. Biofertilizer application reduced fruit dry matter content, total soluble solids and boron concentration, with no effect on fruit firmness and titratable acidity. Biofertilizer application has positive effect on soil mineral N dynamics and soil microflora, altering the content of nutrients in leaves, favoring fruit production.
Azamora penicillana occurrence in sour passion fruit in the state of Minas Gerais
Authors: Pirovani Victor Dias , Fancelli Marilene , Moreira Bruno Magno , Silveira Luiz Flávio Vianna , Pratissoli Dirceu
Published: February 2020

Abstract Azamora penicillana (Walker) (Lepidoptera: Pyralidae) is popularly known as exotic passionflower caterpillar, passionflower web, cloak or pouch. It is considered an emergent pest of passion fruit crop due to damages caused to the plant and management difficulties related to insect habit. This species is recorded for the first time infesting passion fruit in the state of Minas Gerais attacking leaves, fruits and branches. Pest attacks have been widely reported throughout the orchard.
Karl Polanyi and substantivism in economic development
Authors: RODRIGUES WALDECY , SANTOS NAYARA SILVA DOS
Published: February 2020

ABSTRACT A reading of Karl Polanyi’s work gives us a broader and more plural view of the development process beyond the exclusively economic dimension. This scientific text aims to recover the theoretical contribution of Karl Polanyi and its contribution to the understanding of the development process from a plural and substantive conception of economy. The key lesson learned in this research is that regardless of a country’s economic system, one should pay attention to the existing institutional variety and complexity of its cultural and social mosaic. True development will only be achieved if it is structured with effective public policies in order to promote this heterogeneity to the maximum possible social welfare.
Avaliação dos custos econômicos associados aos jovens nem-nem no Brasil
Authors: SHIRASU MAITÊ RIMEKKÁ , ARRAES RONALDO DE ALBUQUERQUE E
Published: February 2020

RESUMO A existência de milhões de jovens que nem estudam nem trabalham, os denominados nem-nem, tem implicações danosas para a sociedade e para a economia. Este estudo foca nos principais custos econômicos associados à ociosidade desses jovens por meio do Propensity Score Macthing. Os resultados revelam que os jovens nem-nem representaram um custo de 0,6% do PIB em 2015. Considerando esse significante custo anual, e a trajetória crescente desse contingente juvenil nos últimos anos, há que se clamar pela implementação de políticas que contenham esse crescimento, a fim de se evitar severos prejuízos de ordem econômica e social no longo prazo.