bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway
Authors: Meng Xiangli , Liu Peng , Wu Yunhao , Liu Xinlu , Huang Yinpeng , Yu Boqiang , Han Jiahong , Jin Haoyi , Tan Xiaodong
Published: June 2019

Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of only 1–4%. Integrin-mediated cell adhesion is critical for the initiation, progression, and metastasis of cancer. In this study we investigated the role of integrin b4 (ITGB4) and its phosphorylation at tyrosine Y1510 (p-ITGB4-Y1510) in the tumorigenesis of pancreatic cancer. We analyzed the expression of ITGB4 and p-ITGB4-Y1510 in pancreatic cancer tissue and cell lines using immunohistochemistry, Western blot, or semi-quantitative reverse transcription PCR. ITGB4 and p-ITGB4-Y1510 were highly expressed in pancreatic cancer (n = 176) compared with normal pancreatic tissue (n = 171). High p-ITGB4-Y1510 expression correlated with local invasion and distant metastasis of pancreatic cancer, and high ITGB4 was significantly associated with poor survival of patients. Inhibition of ITGB4 by siRNA significantly reduced migration and invasion of PC-1.0 and ASPC-1 cells. Overexpression of the mutant ITGB4-Y1510A (a mutation of tyrosine to alanine at 1510 position) in PC-1.0 and ASPC-1 cells not only blocked the ITGB4 phosphorylation at Y1510 but also suppressed the expression of ITGB4 (p < 0.05 vs. wild-type ITGB4). The transfection of PC-1.0 and ASPC-1 cells with ITGB4-Y1510A significantly decreased the level of p-mitogen-activated protein kinase kinase (MEK)1 (T292) and p-extracellular signal-regulated kinase (ERK)1/2 but did not affect the level of p-MEK1 (T386) and p-MEK2 (T394). Overall, our study showed that ITGB4 and its phosphorylated form promote cell migration and invasion in pancreatic cancer and that p-ITGB4-Y1510 regulates the downstream MEK1-ERK1/2 signaling cascades. Targeting ITGB4 or its phosphorylation at Y1510 may be a novel therapeutic option for pancreatic cancer.
Artemisia L. Subgen. Drancunculus (Bess.) Rydb. Taksonlarının uçucu yağ kompozisyonları ve antimikrobiyal özellikleri
Authors: KIRBAĞ Sevda , BAĞCI Eyüp , CİVELEK Şemsettin , KURŞAT Murat
Published: June 2019

Bu çalışmada, Türkiye'nin farklı yerlerinden toplanan ArtemisiaL. cinsinin Drancunculus(Bess.) Rydb. altcinsi taksonlarınınuçucu yağların bileşenleri ve bunların antimikrobiyal özellikleri belirlenmiştir.Uçucu yağlar bitkilerin toprak üstü kısımlarından hidrodistilasyon metodu kullanılarak elde edilmiştir. Antimikrobiyal aktivite oyuk agar metodu kullanılarak tespit edilmiştir.Artemisia campestrisL.var. campestris temel uçucu yağ bileşenleri sırasıyla naftalen (%34.69),b–pinen (%13.29), spatulenol (%7.70), 2,4 hexadien-1-one (%6.99) penta-2,4-dione (%4.96), α -pinen (1.65%), limonen (%1.51) tespit edilmiştir. Artemisia campestris var.marschalliana(Spreng.) Poljak.’dabenzen (%17.34),b–pinen (%10.54), spatulenol (%10.45), 1-phenly-penta-2,4-diyn (%8.06), karyofillen oxid (%6.93), asenaphthylen (6.31%), limonen (4.45%), α-pinen (3.70%), b-mirsen (3.23%)belirlenmiştir. Artemisia campestris L. var. araratica(Novopokr.) Poljak’da b–pinen (%18.32), b–pinen (%8.03), limonen (%5.19), cis-osimen (%2.87), trans-geraniol (1.93), trans-isolimonen (1.86%), kamfor (%1.79) olarak belirlenmiştir. Artemisia scoparia Waldst. & Kit.’da1-phenyl-penta-2,4-diyn (%15.44), benzen (%13.34), b-pinen (%11.85), spatulenol (%11.11), limonen (%6.59), karyofillen oxid (%5.99), α–pinen (%3.73), b-mircen (%3.15), cis-okimen (%2.96) tespit edilmiştir. Artemisiatürlerinin uçucu yağları patojen mikroorganizmaların gelişimlerini farklı oranlarda engellemişlerdir.
A linguist’s reminiscences to identification theory: epistolary of Panteleimon Kulish. Article 1
Authors: Shevchenko Larysa
Published: June 2019

In E. Erickson’s theory of identification the article analyses the epistolary of Panteleimon Kulish – an outstanding Ukrainian culturologist, publisher, writer and translator. The author states that E. Erickson’s theory created the intellectual matrix of a person’s development analysis in the system of psychosocial conditions and circumstances. The scholar studies E. Erickson’s main postulate, namely the correlation of a personality with psychosocial identity. Therefore, a personality can be interpreted in the integrity of various motivations, traditions, values, ideals and their social roles. The author explores the influence of cultural and historical factors on a person’s psycho-emotional and creative structure. The theory of evolution is considered, which, according to E. Erickson, defines eight universal stages of human development. The scholar investigates the principles of development stages, i.e. a) progressive development of a person, which is ready to evolve in the direction of further growth, expansion of the perceived outlook and possibilities of social interaction; b) the development of a person’s social and creative capabilities in coordination with changes in society, when society promotes preservation of interaction trends. The major problem in the analysis of P. Kulish’s creative person is the problem of ethnic identification. The article explores the criteria of P. Kulish’s ethnic identification: existential choice, ways of self-realization, achievement of internal freedom, solving individual-psychological problems of belonging to a certain social strata, realization of a person’s powerful intentions in the national language.
A Story of “Rising Voices” and Intercultural Collaboration
Authors: Maldonado Julie , Lazrus Heather
Published: June 2019

Until recently, the voices and wisdom of Indigenous peoples have been largely excluded from climate change science, decision making, and governance. Encouragingly, a shift has emerged in the last few decades. Today, a number of scientists realize the critical importance and value of Indigenous peoples' wisdom, observations, insights, and knowledge. This shift in awareness is visible in initiatives from climate assessments to university- and agency-based projects. Yet, there are few venues devoted to facilitating this work and to creating an intercultural collaborative process based on courage, respect, justice, equality, and reciprocity that addresses our changing climate. Provisioning that missing space is precisely what the Rising Voices: Climate Resilience through Indigenous and Earth Sciences program sets out to do. This is a story about the development of an intercultural network and how the two co-authors—a public and an environmental anthropologist—came to bear witness, to know, and were called to act.
“We Live in the Water”
Authors: Rehak Jana Kopelent
Published: June 2019

Smith Island historical photographs, public and private, in their intimacy and immediacy, encourage us to think about the relationship between appearance and meaning. This article invites us to think through photographs as primary data in anthropological enquiry about the storying of climate in relation to inscribed, visual social biographies in Smith Island albums. I discuss Islanders' intimate visual, ecological, and sensory knowledge in relation to the changing ecology facing Smith Islanders. Old island photos hold memories that interface individuals and their contemporary social identities. When Smith Islanders view their family photographs, they enter the pictorial history of their island. Reading old family photographs with islanders, as they are archived in albums, boxes, or bags, opens a new space for connection of their sense of self with a sense of place.
Multi-Dimensional Model of the Zone of Proximal Development as a Way to Analyze the Dynamics of the Child’s Development in Learning Activity
Authors: Zaretsky V.K. , Nikolaevskaia I.A.
Published: June 2019

This paper describes the possibility of using a multi-dimensional model of the zone of proximal development for a qualitative analysis of the cognitive-personal dynamics of a child’s development in the process of overcoming learning difficulties. The model was developed in the framework of the reflective activity approach to the provision of advisory assistance. The use of this model for analyzing the dynamics of the cognitive-personal development of a child makes it possible to establish “developmental steps” recorded as new formations in the cognitive abilities of the child and to determine the personal characteristics associated with the primary cognitive changes. A case of providing counseling psychological and pedagogical assistance by means of a reflective-activity approach was considered, the situation was assessed at the beginning of the counseling process and after 8 sessions, the main changes were reflected. To describe the initial and subsequent picture and the changes that occurred, a multi-dimensional model of the zone of proximal development was used.
Tipik Çölyak hastalığı sadece buz dağının görünen kısmı mı?
Authors: CANAN Oğuz
Published: June 2019

-
Central nervous system involvement in acute graft versus host disease
Authors: KÜPELİ Serhan
Published: June 2019

-
İdiyopatik konjenital tek taraflı vokal kord paralizisi: yenidoğanda tekrarlayan pnömoni ataklarının nadir bir nedeni
Authors: GÜLCAN Hande , ÇETİNKAYA Bilin , TÖRER Birgin , ÖZER Fulya
Published: June 2019

-
Comments on ‘Coexistence of diaphragm eventration and multiple organ anomalies after sigmoid volvulus’
Authors: ATAMANALP Sabri Selçuk
Published: June 2019

-
Governance and Domestic Investment in Africa
Authors: Iheonu Chimere Okechukwu
Published: June 2019

The study empirically examined the impact of governance on domestic investment in 16 African countries with a balanced panel data set, between the years 2002 and 2015. The study employed six unbundled governance indicators from the World Bank, World Governance Indicators and constructed three bundled governance indicators using the Principal Component Analysis. The Driscoll and Kraay Fixed Effects model which accounts for serial correlation, groupwise heteroskedasticity and cross-sectional dependence were employed with empirical results revealing that all the indicators of governance positively and significantly influence domestic investment in Africa, except for government effectiveness which happens to be insignificant. Also, Voice/Accountability and the Control of Corruption exert more influence on domestic investment as indicated by their coefficient values. Furthermore, economic growth is also an important factor in explaining domestic investment in Africa. Policy recommendations are discussed.
Economic Analysis of Supply Functions, Private Returns to Investment in Education and Skill Mismatch in Egypt
Authors: Biltagy Marwa Shibl
Published: June 2019

Education provides good health, empowerment and employment to all people in the society. Accordingly, education can make a lifelong difference in individuals’ lives. It is proved that, on average, there is a positive relationship between each additional year of schooling and the income of an individual. The main objective of this paper is to estimate the demand and supply functions for schooling in Egypt using the data of the Egypt Labor Market Panel Survey 2012. It is estimated that the private rate of return to education is 4.5%. Moreover, the rate of return to the number of years of experience is 2.6%, i.e. each additional year of experience will increase the earnings of an individual by 2.6% on average. It is concluded that individuals from poor families have an increased likelihood of receiving financial aid, which decreases their discounting rate of interest.
BALIKESİR İLİ GÖNEN İLÇESİ EKONOMİK DEĞERLERİNİN ANALİZİ
Authors: SELVİ HANİŞOĞLU Gülay
Published: June 2019

Ülkelerin
ekonomik kalkınmasında ulusal kalkınma politikaların yanısıra bölgesel veya
yerel kalkınma politikaları ve stratejileri etkili olmaktadır. Bölgelerin
kapasitelerinin ortaya çıkarılarak, bu kapasitelerle uyumlu uygulanacak model
ve araçlarla bölgesel olarak yaratılan değerler arttırılabilmektedir. Bu
değerlerin etkinliğinin arttırılması ile hem bölgelerin kalkınmasına hem de
ulusal ekonomiye önemli katkılar sağlanabilmektedir. Çalışmamızda öncelikle
ekonomik büyüme, kalkınma ve bölgesel kalkınmaya ilişkin teoriler
özetlenmiştir. Daha sonra Gönen ilçesinin demografik yapısı ve genel ekonomik
faaliyetleri hakkında bilgilendirme yapılmıştır. Balıkesir ili Gönen ilçesi
tarım, hayvancılık, sanayi, turizm ve el sanatları üretimi ile ekonomik değer
yaratan bir yöremizdir. İlçemizin bu alanlarda yarattığı ekonomik değerin ne
kadar olduğu, yıllar itibarıyla nasıl değişiklikler gösterdiği çalışmamızın ana
eksenini oluşturmaktadır. Gönen’de yaratılan ekonomik değerin ne kadarının
hangi ekonomik faaliyet alanından geldiği ve yıllar itibarıyla bu yapıda
değişiklik olup olmadığı analiz edilmektedir. Ekonomik değer yaratan
sektörlerin fiziksel anlamda kapasiteleri ve ürettikleri ekonomik değerler
ortaya çıkarılmıştır. Yıllar itibarıyla üretim miktarları alınmış, bu
miktarların parasal değerleri hesaplanarak yıllar itibarıyla yaratılan toplam
ekonomik değerlere ulaşılmıştır. Daha sonra bu alanlarda önümüzdeki yıllarda
ortaya çıkabilecek gelişmelerin neler olabileceği değerlendirilmiştir.
İlçemizde var olan potansiyelin nasıl arttırılabileceği, yapılabilecek
iyileştirmelerin neler olabileceği, uygulanabilecek yeni modellerle hangi
alanlarda gelişim sağlanabileceğine ilişkin değerlendirme ve öneriler
oluşturulmuştur. Bu değerlendirme ve öneriler bölgesel paydaşlarla, bölgede
yaşayan, bölgede çalışan kişi, kurum ve şirketlerle ortak yapılan çalışmalar
sonucu oluşturulmuştur. Bu nedenle gerçekçi ve karar vericilere, politika
uygulayıcılara yol gösterici nitelik taşımaktadır. Çalışmamızda Balıkesir ili
Gönen ilçesinin ekonomik kapasitesinin, değerlerinin neler olduğu ve bu
ekonomik değerlerin daha verimli kullanılarak bölgenin kalkınmasına katkısının
nasıl arttırılacağı incelenmektedir. Analiz ve değerlendirmelerde Türkiye
İstatistik Kurumu, Gönen İlçe Tarım Müdürlüğü, Gönen Ticaret Odası, Türkiye
Ziraat Odaları Birliği, Bilim Sanayi ve Teknoloji Bakanlığı Balıkesir İl
Müdürlüğü verileri kullanılmıştır. Gönen bölgesine özgü olarak yapılan bu
çalışmanın bölgenin orta vadeli büyüme ve kalkınmasına katkı yapması dileğimiz
ve beklentimizdir. Bundan sonrasında üniversitelerle yapılacak işbirlikleri ile
Gönen ve diğer yöreler için bölge kalkınmasına ivme kazandırılması yönünde
çabaların sürdürülmesi faydalı olacaktır.
La protección de negocios a través de los acuerdos de no competencia en materia laboral
Authors: Carrasco Torrontegui Pablo René , Pozo Veintimilla Patricio
Published: June 2019

Los empresarios tienen el interés comercial de proteger su negocio y evitar que sus extrabajadores realicen actividades económicas que compitan de forma directa, o a través de terceros, con su negocio tras la terminación de la relación laboral. Uno de los mecanismos de protección más utilizados es el acuerdo de no competencia, que establece la limitación del extrabajador de poder concurrir en el mercado donde opera su exempleador. Dado que este acuerdo contiene una limitación al ejercicio de derechos laborales y económicos garantizados en la Constitución de la República, y frente a la falta de una normativa que regule de forma precisa estos acuerdos en el ordenamiento jurídico ecuatoriano, la doctrina y jurisprudencia internacional han desarrollado los requisitos que deberían contener estos acuerdos para su validez, como son: la existencia de un interés comercial legítimo del exempleador, una compensación económica adecuada alextrabajador, delimitación temporal, acuerdo por escrito, y limitación del mercado relevante únicamente en el segmento o actividades que entran en competencia.
Canadá y la crisis de Venezuela
Authors: Grenier Yvon
Published: June 2019

En los últimos años, Canadá ha salido de su zona de confort en los asuntos hemisféricos para hablar y actuar enérgicamente, como lo expresó la ministra de relaciones exteriores, Chrystia Freeland, en solidaridad con “el pueblo de Venezuela y su deseo de restaurar la democracia y los derechos humanos en Vene­zuela”. Con sus socios del Grupo de Lima, Ca­nadá impuso sanciones al régimen de Maduro, reconoció a Juan Guaidó como presidente interino y convocó a elecciones libres y justas lo antes posible. El artículo identifica posibles factores que explican la política de Canadá. La propuesta principal es que la crisis de Venezue­la presenta una combinación extraordinaria de factores nacionales e internacionales que hacen que la participación en un impulso multilate­ral y diplomático para el restablecimiento de la democracia sea una opción ambiciosa pero, sensata para Canadá. El artículo también pre­senta las críticas a esta política y analiza el tema de los derechos humanos y la promoción de la democracia en el contexto más amplio de la política exterior canadiense.
Regionalismo Sul-Americano e defesa: os impactos da inflexão na Unasul e no CDS Artur Cruz Bertolucci
Authors: Cruz Bertolucci Artur , Da Motta Baptista João Victor , Dias de Paula Leonardo
Published: June 2019

O arrefecimento do diálogo intergoverna­mental nos espaços de concertação política da Unasul, e em específico em seu CDS, podem ser interpretados como um desafio às análises mais otimistas quanto às possibilidades de cooperação na América do Sul. No presente texto, analisamos o processo mais recente de esvaziamento do CDS da Unasul a partir do marco teórico dos estudos de integração regio­nal e do instrumento analítico dos Complexos Regionais de Segurança. Argumentamos que o arranjo de cooperação regional instituído atra­vés da Unasul permanece volátil aos esforços e incentivos governamentais.
РАЗРАБОТКА ДИЗАЙНА ГИДРОДИНАМИЧЕСКОГО ИССЛЕДОВАНИЯ В УСЛОВИЯХ КАРБОНАТНОГО КОЛЛЕКТОРА
Authors: Давыдова Анастасия Евгеньевна , Щуренко Александр Александрович , Дадакин Никита Михайлович , Шуталев Артем Дмитриевич , Квеско Бронислав Брониславович
Published: June 2019

Актуальность исследования обусловлена необходимостью совершенствования методов гидродинамических исследований скважин вследствие неоднозначности интерпретации результатов в условиях карбонатного коллектора. Приоритетами при проведении гидродинамических исследований скважин являются максимальное качество получаемой информации о фильтрационно-емкостных свойствах пластов и минимальные потери добычи нефти в ходе остановки скважин на исследования. С целью выполнения данных задач актуальной является разработка дизайна гидродинамических исследований скважин, предлагаемая в статье. Дизайн позволит обеспечить комплексный подход к моделированию процесса проведения исследований и прогноза получаемых данных. Цель: разработать дизайн гидродинамических исследований скважин с целью оптимизации времени проведения исследований и сокращения периода остановки скважин на этапе опытно-промышленной эксплуатации; подтвердить экономическую эффективность представленной методики.  Объекты: скважины Т-23, Т-361, Т-388 месторождения A, продуктивные отложения которого преимущественно представлены кавернозно-трещиноватыми карбонатными породами рифейского возраста. Методы. Поставленные задачи исследования решались теоретически и экспериментально в промысловых условиях. При этом был выполнен анализ публикаций по данной проблеме; проведены промысловые гидродинамические исследования скважин, вскрывающих низкопроницаемый карбонатный коллектор; выполнено моделирование гидродинамических исследований, выполнены сравнительные расчёты по обработке результатов с помощью программного комплекса Saphir компании «KAPPA Engineering». Результаты. Приведены результаты разработки дизайна гидродинамических исследований в условиях карбонатного коллектора. Проанализированы данные гидродинамических исследований для 12 скважин, эксплуатирующих рифейские карбонатные отложения, за период с 2005–2008 гг. представлены результаты по трем скважинам: Т-23, Т-361, Т-388. Представлена методика моделирования гидродинамических исследований в программном комплексе Saphir компании «KAPPA Engineering». Приведен пример расчета времени стабилизации при исследовании скважины методом установившихся отборов, а также оценка оптимального времени регистрации кривой восстановления давления. Также приведено сравнение стандартной методики, которой руководствуются при испытании скважины – РД (руководящий документ) 153-39.0-109-01 «Методические указания по комплексированию и этапность выполнения геофизических, гидродинамических и геохимических исследований нефтяных и нефтегазовых месторождений», с методикой, представленной в статье. На основе данного сравнения была установлена экономическая эффективность.
ОСОБЕННОСТИ ЭЛЕМЕНТНОГО СОСТАВА FILIPENDULA ULMARIA (L.) MAXIM (ROSACEAE) НА ТЕРРИТОРИИ НОВО-УРСКОГО ХВОСТОХРАНИЛИЩА В КЕМЕРОВСКОЙ ОБЛАСТИ
Authors: Горбатюк Екатерина Александровна , Барановская Наталья Владимировна , Жданов Вадим Алексеевич
Published: June 2019

Актуальность исследования обусловлена необходимостью получения комплексной информации о влиянии радикальных изменений биогеохимического фона в районах распространения хвостохранилищ горнорудного производства с целью прогнозирования путей миграции токсичных компонентов. Цель: выявление изменений в элементном составе корневой и надземной части Лабазника вязолистного (Filipéndula ulmária (L.) Maxim.) и установление индикаторных показателей техногенного влияния хвостохранилища руд Ново-Урского месторождения. Задачами исследования являются: определение коэффициентов концентраций химических элементов относительно фоновых значений, изучение особенностей пространственного распределения элементов в надземной и корневой частях лабазника вязолистного на территории хвостохранилища, установление коэффициентов аккумуляции химических элементов в корневой части лабазника вязолистного по отношению к надземной. Методы. Сбор растительного материала произведен на флангах Ново-Урского хвостохранилища. Элементный состав лабазника вязолистного определен методом масс-спектрометрии с индуктивно связанной плазмой (ИСП-МС) в лаборатории аналитического центра «Плазма» (г. Томск) по аттестованным методикам. Обработка аналитических данных выполнялась с помощью программ Statistica (6.0) и Excel. Картосхемы распределения элементов в надземной и корневой частях лабазника вязолистного построены в программах Surfer (11) и CorelDRAW (16). Результаты. На примере Ново-Урского хвостохранилища в Кемеровской области изучено накопление 67 химических элементов в лабазнике вязолистном. Рассчитаны коэффициенты концентраций элементов относительно фоновой точки и кларка ноосферы. Составлены геохимические ряды, отражающие избыточное накопление таких элементов, как Zn, Ba, Pb, Tl, Se, Ag, W, Hg, Au, P, превышающих фоновые значения в 5 и более раз. Картосхемы пространственного распределения химических элементов в лабазнике вязолистном показали наиболее высокие концентрации элементов в районе расположения отвала переработки окисленных руд и зоны потока рассеяния. Представлены коэффициенты аккумуляции химических элементов в корневой части лабазника вязолистного по отношению к надземным. Выявлено повышенное содержание химических элементов в корнях примерно в 80 % случаев.
ПРИРОДНО-ТЕХНОГЕННЫЕ КАТАСТРОФЫ КАК ПРОЯВЛЕНИЯ ГЕОДИНАМИЧЕСКОЙ НЕСТАБИЛЬНОСТИ ЗЕМНОЙ КОРЫ
Authors: Борисов Константин Иванович , Горшков Лев Капитонович , Софьин Алексей Петрович , Федорова Людмила Анатольевна
Published: June 2019

Актуальность. Геодинамическая нестабильность – причина многих природных катастроф: землетрясений, извержений вулканов, оползней, цунами. Природные катастрофы могут инициировать техногенные аварии (обрушения зданий и сооружений, взрывы на шахтах, нарушения целостности плотин и др.) и, наоборот, техногенные процессы могут вызывать появление новых природных объектов, например, с ними связано создание искусственных водохранилищ. Широко распространенная в мире добыча нефти и газа может провоцировать подвижки в земной коре с трагическими последствиями. Особенности условий для активизации геодинамической нестабильности определяют уровень безопасности персонала технических объектов и качество эксплуатации сооружений, систем и агрегатов. Случайный характер процессов в земной коре в значительной мере формирует возможность прогнозирования техногенных катастроф и проведения мероприятий для парирования негативных факторов, связанных, в том числе, с безопасностью персонала и населения. Рекомендации по предупреждению и прогнозу природно-техногенных катастроф и условия их возникновения основаны на сопоставлении различных точек зрения на активизацию геодинамической нестабильности Земли, а также выявлении степени влияния на нее сезонной периодичности характерных процессов. Обоснован уровень значимости параметров движения Земли в формировании условий активизации геодинамической нестабильности. Однако, современное состояние вопроса диктует необходимость дополнительных исследований в данной области, что частично восполняет данная статья. Цель: определить и предложить вариант подхода к анализу условий возникновения катастрофической ситуации. Объекты: геодинамические процессы в земной коре и варианты комбинаций условий для их возникновения. Методы: обзор и анализ существующей научно-технической информации по проблеме геодинамической стабильности земной коры и постановка задач исследований. Результаты. Выявлены и обоснованы причины возникновения аварийных ситуаций, связанных с геодинамическими процессами в земной коре.
Utilidad de la teoría de la conducta planificada para entender el consumo de frutas y verduras: evidencia de estudios en adultos y adolescentes chilenos = Usefulness of the theory of planned behavior to understand the consumption of fruits and vegetables: evidence of studies on Chilean adults and adolescents
Authors: Peña-y-Lillo Macarena Sofia
Published: June 2019

Este artículo presenta dos estudios cuantitativos con diseño descriptivo no experimental. El primero corresponde a una encuesta transversal cara a cara a adultos de 18 a 78 años de segmentos socioeconómicos medios y bajos (N = 250). El segundo corresponde a  una encuesta longitudinal autoaplicada en adolescentes de sexo femenino de 12 a 18 años (N = 751). El propósito de ambos estudios fue explorar las asociaciones de los constructos de la teoría de la conducta planificada (TCP) en el contexto del consumo de frutas y verduras en la población chilena. Los datos se analizaron utilizando regresiones múltiples y jerárquicas. En los dos estudios se encontró que las actitudes, normas sociales y percepciones de control estaban significativamente asociadas con las intenciones. Las intenciones, en tanto, tenían una asociación transversal con la conducta. Los hallazgos de este estudio subrayan la utilidad de la TCP para guiar intervenciones para promover una alimentación saludable, en especial, la importancia de las actitudes y las percepciones de control.Palabras clave: dieta saludable; actitudes; percepciones de control conductual; auto-eficacia; promoción de la salud.Abstract Introduction: The theory of planned behavior (TPB) proposes that human behavior can be explained as a function of intentions to perform a given behavior, which in turn are determined by attitudes, normative perceptions and perceptions of control. The model has been extensively recommended and utilized to guide the design of public health communication interventions. Goals: The purpose of this work is to explore the associations of the TPB constructs in the context of fruit and vegetable consumption in the Chilean population. Methods: Two quantitative studies with a descriptive non-experimental design were conducted. The first corresponds to a face-to-face cross-sectional survey of adults 18 to 78 years of medium and low socioeconomic status (N = 250). The second corresponds to a longitudinal self-applied survey of female adolescents 12 to 18 years old (N = 751). The data were analyzed using multiple and hierarchical regressions. Results: In both studies, it was found that attitudes, norms and perceptions of control were significantly associated with intentions. Intentions, in turn, had a cross-sectional association with behavior. Conclusion: This study’s findings underscore the usefulness of the TPB to guide interventions aimed at promoting healthy eating, especially the importance of attitudes and perceptions of control for this purpose.Keywords: healthy diet; attitudes; perceived behavioral control; self-efficacy; health promotion.
El lenguaje y la educación alimentaria. Resultados de un cuestionario poblacional = Language and nutritional education. Results of a population survey
Authors: Tejedor Martín Francisco Javier , Pérez Llano Begoña , Mijancos Gurruchaga María Teresa , Gonxález Panero Pilar
Published: June 2019

A efectos de valorar el conocimiento y uso de expresiones relacionadas con la alimentación como «comida basura», «guarrerías» y «snacking», y su importancia en la educación alimentaria se ha realizado un estudio utilizando un cuestionario entre individuos residentes en España. Los resultados permiten concluir que existe casi una identificación entre las expresiones «comida basura» y «comida rápida», y un alto grado de acuerdo entre «comida basura» y «alimentos poco saludables». Los principales alimentos incluidos son «refrescos», seguidos de «perritos calientes», «hamburguesa», «patatas fritas» y «pizza». Hay un amplio acuerdo en los dos principales motivos por los que se denomina «basura» a un tipo de comida: porque «favorece la obesidad», y porque «puede producir problemas cardiocirculatorios».El 96.3% conoce el término «guarrerías» relacionado con la alimentación, se asocia a «alimentación no saludable». Se relaciona con «chucherías», «golosinas», «bollería», y menos con «patatas chips», «snack salados» o «palomitas».«Snacking», sólo es conocido por el 52.87% de los encuestados, relacionado con «picoteo entre horas» y «consumo habitual de snacks».Se concluye que el uso de expresiones «comida basura» o «guarrerías» puede ser útil en campañas de concienciación sanitaria en el ámbito de la educación alimentaria.Palabras Clave: Lenguaje; Alimentación; Educación alimentaria; Comida basura; Guarrerías; SnackingAbastractIt is intended to assess the use and meaning of food-related expressions in Spanish language such as «comida basura» (junk food), «guarrerías» or «snacking». Methodology: A questionnaire has been developed and answered by residents in Spain. Results: An identification has been observed between the expressions «junk food» and «fast food», and a high agreement between «junk food» and «unhealthy food». The main foods included in this term are «refreshing drinks», followed by «hot dogs», «hamburger», «chips» and «pizza». There is broad agreement that the reason «food» is called «junk» is because it «promotes obesity», and because «it can cause cardiocirculatory problems». The term «guarrerías» related to food is known by 96.3% of surveyed, is related to foods such as «candies», «goodies», «buns», «chips», «salty snacks» or «popcorn». The consumption of «guarrerías» is associated with «unhealthy food».«Snacking» is only known by 52.87% of participants, is related to «eat between meals» and «habitual consumptionof snacks». Conclusion: The use of expressions such as «junk food» (comida basura) or «guarrerías» can be useful in nutritional and health education.Keywords: Language; Healthy nutrition; Nutritional education; Junk food; Snacking.
Oficina de comunicación a distancia del Hospital de Pediatría “Prof. Dr. Juan P. Garrahan” – más de 20 años construyendo telemedicina = Outreach Communication Office of Hospital de Pediatría “Prof. Dr. Juan P. Garrahan” – more than 20 years building telemedicine
Authors: Savignano Maria Celeste , Castelli Mauro , Kassab Silvia , Luna Antonio
Published: June 2019

Introducción: El Hospital de Pediatría “Prof. Dr. Juan P. Garrahan” ha sido pionero en la atención de la salud de la población infantil del país y de Latinoamérica. El 53% de los pacientes que concurren al hospital viven más allá del área metropolitana de Buenos Aires. En agosto de 1997, se creó la Oficina de Comunicación a Distancia como una herramienta para sostener la continuidad asistencial de los pacientes de áreas remotas; su apertura significó el embrión del primer programa de telemedicina del país. Objetivos: Promover la construcción de redes integradas de servicios de salud. Impulsar nuevos procesos que mejoren el acceso a la salud. Metodología: Basados en la lógica de redes integradas de servicios de salud con la incorporación de las tecnologías de la información y la comunicación. Resultados: Desde 1997 hasta el primer semestre de 218 se crearon 283 OCD. Se asistieron más de 70.000 consultas asincrónicas y se realizaron más de 5000 videoconferencias. Conclusiones: La modalidad de comunicación a distancia y telemedicina estimula el trabajo colaborativo interinstitucional favoreciendo la atención de los pacientes en origen.Palabras clave: Oficina de comunicación a distancia (OCD); telemedicina; redes; tecnologías de la información y la comunicación (TICS).Abstract Introduction: Hospital de Pediatría “Prof. Dr. Juan P. Garrahan” has been a Pioneer in health care for children in Argentina and Latin America. Overall, 53% of the patients that are covered by the hospital live outside the metropolitan area of Buenos Aires. In August 1997, the Outreach Communication Office (OCO) was created as a tool to sustain continuous care for patients living in remote areas; its inauguration was the seed for the first telemedicine program in the country. Objectives: To promote the development of networks of health-care services. To initiate processes to improve Access to health care. Methods: Development of comprehensive health-care networks with the incorporation of information and communication technologies. Results: Between 1997 and the first semester of 218, 283 OCO’s were created. Overall, 70,000 asynchronous consultations were conducted and more than 5000 videoconferences were held. Conclusions: The modality of outreach communication and telemedicine encourages interinstitutional collaboration favoring patient care at their site of origin.Keywords: Outreach Communication Office (OCO); Telemedicine; Networks; Information and Communication Technology (ICT).
Comportamiento de la ciudadanía respecto a la información sobre salud: exposición, acceso y usos = The behavior of citizens regarding health information: exposure, access and uses
Authors: Revuelta Gema
Published: June 2019

Introducción: Los comportamientos de la ciudadanía respecto a la información de salud pueden influir en sus relaciones con otras personas y en sus propias decisiones.Objetivos: Aumentar la comprensión sobre los cambios en los comportamientos de los ciudadanos españoles respecto a la información sobre salud entre 2014 y 2018.Metodología: Se han realizado 6 grupos focales con ciudadanos (N=31) y 4 con comunicadores especializados en salud (N=23). Las transcripciones se han codificado y analizado con la ayuda del programa Atlas.ti 8.Resultados: En 2014, las redes sociales comenzaban a ocupar un papel central en el acceso a la información sobre salud, especialmente entre los más jóvenes. En 2018, en opinión de los comunicadores, aunque hay más contenidos de calidad online, las estrategias comerciales de las redes hacen que los ciudadanos estén más expuestos a fake-news (incluyendo las pseudoterapias) y a contenidos superficiales (como la imagen corporal). Los temas que interesan a la población han cambiado y también su comportamiento respecto a la información. El uso de la información online en la relación médico-paciente no parece haber variado.Conclusión: En 4 años se han producido transformaciones en la exposición y el acceso a la información de salud que pueden tener consecuencias considerables.Palabras Clave: comunicación de salud; redes sociales; relación médico-paciente; fake-news.AbstractIntroduction: The behavior of citizens regarding health information can influence their relationships with other people and their decisions.Objectives: To increase the understanding of behavioral changes of Spanish citizens regarding health information between 2014 and 2018.Methodology: Six focus groups were organized with citizens (N = 31) and four with specialized health communicators (N = 23). The transcripts have been coded and analyzed with Atlas.ti 8 software.Results: In 2014 social networks began to occupy a central role as a means of access to health information, especially among the youngest. From the opinion of communicators, in 2018 there is now more quality information online, but the commercial strategies of the social networks encourage the exposure of citizens to fake-news (including pseudo therapies) and superficial contents (i.e. body image). Citizens have changed their issues of interest and their behavior regarding health information. The use of online information within the doctor-patient relationship do not seem to have changed.Conclusion: In four years there have been changes in the exposure and access to health information that can have considerable consequences.Keywords: health communication; social networks; doctor-patient relationship; fake-news
La importancia de informar ante la ansiedad y la resiliencia de pacientes que van a ser sometidos a una colonoscopia = The importance of reporting to the anxiety and the resilience of patients will undergo a colonoscopy
Authors: Olmo-Conesa Juana María , Gómez-Díaz Magdalena
Published: June 2019

Introducción: La colonoscopia es una técnica beneficiosa pero no deja de ser un procedimiento incómodo, donde el dolor y el miedo a lo desconocido han hecho que este procedimiento genere cierto grado de ansiedad en el paciente. Objetivos: Se trata de evaluar el nivel de ansiedad y resiliencia en los pacientes que van a ser sometidos a colonoscopia, y comprobar si el conocimiento y la información recibida influye en dichas variables. Metodología: Se trata de un estudio observacional, descriptivo, transversal y prospectivo, realizado en una muestra de 100 pacientes, 50 sometidos a la prueba con sedación consciente y 50 con sedación profunda, que acudieron a la realización de una colonoscopia. Los instrumentos de evaluación utilizados fueron el State-Trait Anxiety Inventory (STAI) y el Connor-Davidson Resilience Scale (CD-RISC-10). Resultados: El 52% de los pacientes obtuvieron una ansiedad-estado elevada. Este nivel de ansiedad se relacionó de manera estadísticamente significativa con haber recibido información o no (p=.00) y con el nivel de la misma, suficiente o insuficiente (p=.00). Y los pacientes más resilientes resultaron ser aquellos que sí conocían la prueba o recibieron información sobre la misma. Conclusión: Podemos observar que a más información menos ansiedad y mayor nivel de resiliencia frente a una colonoscopia.Palabras clave: ansiedad; resiliencia; colonoscopia; enfermería; información; sedación consciente;sedación profunda.AbstractIntroduction: Colonoscopy is a highly demanded technique due to its benefits, but it is nevertheless an uncomfortable procedure where pain and fear of the unknown can create a certain degree of anxiety. Objectives: The main objective of this study is to evaluate the level of anxiety and resilience in patients going to undergo colonoscopy, and check if the received information and knowledge affects these variables. Methodology: This is an observational, descriptive, transversal and prospective study. The study sample included 100 patients, 50 tested with conscious sedation and 50 with deep sedation, who underwent a colonoscopy. The assessment tools used were: State-Trait Anxiety Inventory (STAI)y Connor-Davidson Resilience Scale (CD-RISC-10). Results: 52% of the sample experienced a highdegree of anxiety. This level of anxiety related statistically significantly with receiving information or not (p =. 00) and with the same level, sufficient or insufficient (p =. 00). And patients more resilient turned out to be those that yes knew the test or were briefed on it. Conclusion: We can conclude that more information less anxiety and greater level of resilience against a colonoscopy.Keywords: anxiety; resilience; colonoscopy; nursing; information; conscious sedation; deep sedatio
Exclusive Breastfeeding Associated with the Reduction of Acute Respiratory Tract Infections in Toddlers with High-Risk Factors
Authors: Bakar Abu , Rohma Elfira Fitria , Kurnia Iqlima Dwi , Qomariah Siti Nur
Published: June 2019

Introduction: Acute respiratory tract infections (ARI) is a disease that is the primary cause of death, especially in children. Toddlers can be prevented from developing ARI with increased immunity. Giving breast milk can increase children's immunity, but there are still children who experience ARI. This study aimed to explain the differences in Acute Respiratory Tract Infections (ARI) events in toddlers who are exclusively and non-exclusively breastfed.Methods: The research design used was descriptive-comparative with a retrospective design. The population in this study were all children one to three years of age. A sample of 158 toddlers was recruited by a purposive sampling technique. Data retrieval was done with the criteria that the child had visited a public health centre (puskesmas) or integrated health care service post (posyandu), and does not suffer from a disease such as asthma or have any allergies. The variables were measured using a questionnaire and observation sheet. Data analysis was done by a chi-square test and binary logistic regression.Results: The results showed that there were differences in ARI incidence in toddlers (one to three years) who were exclusively and non-exclusively breastfed with a value of p = 0.003. The air pollution factor proved to be significant, dominantly affecting the incidence of ARI.Conclusion: Differences in ARI incidence in toddlers who are exclusively and non-exclusively breastfed is possible due to air pollution factors. Key implications for nursing practice from this research are improving services, and prevent the occurrence of ARI.
Development of the Mind-Body-Spiritual (MBS) Nursing Care Model for Coronary Heart Disease Patients
Authors: Kurniawati Ninuk Dian , Nursalam Nursalam , Suharto Suharto
Published: June 2019

Introduction: Patients with coronary heart disease (CHD) may experience various physical, psychological or spiritual issues. A holistic mind-body spiritual nursing care (MBS) model is needed to help patients' cope with the issues. This study aimed to develop an MBS nursing care model for CHD patients.Method: The study employed a crossectional design with 110 CHD patients participated in the study. Respondents were asked to fill out questionnaires to gather the required data. Criteria for respondent selection were Moslem, aged 40-75 year, medical diagnosis of CHD, and haemodynamically stable. The independent variables were focal, contextual and residual stimuli, while the dependent variables were coping and spirituality. Data were analyzed using partial least square.Results: The results show that the mind-body-spiritual nursing care formed focal stimuli. Spirituality is formed by focal, contextual, residual stimuli and coping style. Nursing care significantly affects spirituality, shown by T-statistics of 6.795. Spirituality can be explained by patience, endeavour toward wellness, and offer the results only to God by 72%, while the rest is explained by other factors.Conclusion: MBS nursing care model has a strong relationship with spirituality. This model needs to be applied in a further research to see its effectiveness in improving spirituality and expression of cardiovascular risk inflammatory markers.
HIV/AIDS-Related Knowledge and Willingness to Participate in Voluntary Counseling and Testing among Health Sciences University Students
Authors: Sari Ni Putu Wulan Purnama , Parut Anselmus Aristo
Published: June 2019

Introduction: Health sciences university students (HSUS) are susceptible to HIV infection due to frequent contact with patients whose HIV status is unknown. This study aimed to compare the HIV/AIDS-related knowledge and the willingness to participate in VCT among HSUS, analyzing the differences between groups, and correlation and effect between variables. Methods: This cross-sectional study involved 357 HSUS from the faculty of nursing, pharmacy, psychology and medicine at an accredited university. Samples were selected using simple random sampling. Data analysis used descriptive statistic, Pearson correlation, one-way ANOVA test, and linear regression test (α<0.05).Results: Most respondents were 20-21 years old single female who still live with parents, exposed to HIV/AIDS material twice/more via academic activities; lack of HIV/AIDS-related knowledge (51.5%), highest mean found in medical students (73.1%); willing enough to participate in VCT (83.5%),  highest mean found in nursing students (86.4%). No correlation found between variables (p=0.101), and the regression model was not significant (p=0.101). HIV/AIDS-related knowledge contributed only 0.8% influence on the willingness to participate in VCT among HSUS (R2=0.008), other unidentified factors possibly play a more important role.Conclusion: Besides knowledge, other factors like demographic factors, social determinants, close person, health education, fear, and HIV-related stigma may affect the willingness to participate in VCT among HSUS. HSUS's knowledge about HIV/AIDS was low but their willingness to participate in VCT was quite high. HIV/AIDS-related knowledge has a slight contribution in determining HSUS's willingness to participate in VCT. Further analysis of other potential factors is needed to determine stronger predictors.
Perceived Benefits and Intakes of Protein, Vitamin C and Iron in Preventing Anemia among Pregnant Women
Authors: Triharini Mira , Nursalam Nursalam , Sulistyono Agus , Adriani Merryana , Hsieh Pei-Lun
Published: June 2019

Introduction: Nutritional adequacy is essential in ensuring the normal growth and development of the fetus. Perceived benefits will be able to strengthen pregnant women to meet optimum nutritional intake to prevent anemia. Adequacy of protein, vitamin C and iron will reduce the risk of iron deficiency anemia in pregnancy. This study aims to examine the association between perceived benefits with protein, vitamin C, and iron intake in preventing pregnancy anemia.Methods: This study used a cross-sectional design and was conducted in August-October 2017 among105 pregnant women. This study used the multistage random sampling method. The population of this study was pregnant women who had antenatal care in four Community Health Centre in Surabaya namely Jagir, MedokanAyu, SidotopoWetan, and Gundih. Results: The average daily protein intake was 76.34 (SD = 35.88) gram/day. There was a significant association between perceived benefits with protein intake (r = 0.272; p = 0.005). The average daily vitamin C intake was 90.67 (SD = 116.54) mg/day. There was no significant association between perceived benefits and vitamin C intake (r = 0.175; p = 0.074). The average daily iron intake was 64.73 (SD = 23.13) mg/day. There was a significant association between perceived benefits and iron intake (r = 0.219; p = 0.025).Conclusion: The knowledge of pregnant women about the benefits of nutrition will affect the adequacy of pregnancy nutrition. Health workers need to provide health education on the importance of nutrition for pregnant women to prevent anemia during pregnancy.