bluuebunny/crossref_metadata_2025 huggingface dataset:
Le contrôle des vaccins destinés aux animaux et la certification des réactifs biologiques, premières démarches vers l’Assurance Qualité
Authors: Fédida Maurice
Published: November 2017

À l’aide d’exemples tirés de son expérience personnelle, l’auteur montre que le contrôle des vaccins et la certification des réactifs biologiques ont été, bien avant leur formalisation, des démarches vers l’Assurance Qualité, devenue aujourd’hui une nécessité. Les exemples relatifs aux vaccins concernent la fièvre aphteuse et la rhinotrachéite bovine infectieuse. Pour la certification des réactifs, deux exemples sont fournis, la leucose bovine enzootique et la rhinotrachéite bovine infectieuse.
Vegetation greenness and land carbon-flux anomalies associated with climate variations: a focus on the year 2015
Authors: Yue Chao , Ciais Philippe , Bastos Ana , Chevallier Frederic , Yin Yi , Rödenbeck Christian , Park Taejin
Published: November 2017

Abstract. Understanding the variations in global land carbon uptake, and their driving mechanisms, is essential if we are to predict future carbon-cycle feedbacks on global environmental changes. Satellite observations of vegetation greenness have shown consistent greening across the globe over the past three decades. Such greening has driven the increasing land carbon sink, especially over the growing season in northern latitudes. On the other hand, interannual variations in land carbon uptake are strongly influenced by El Niño–Southern Oscillation (ENSO) climate variations. Marked reductions in land uptake and strong positive anomalies in the atmospheric CO2 growth rates occur during El Niño events. Here we use the year 2015 as a natural experiment to examine the possible response of land ecosystems to a combination of vegetation greening and an El Niño event. The year 2015 was the greenest year since 2000 according to satellite observations, but a record atmospheric CO2 growth rate also occurred due to a weaker than usual land carbon sink. Two atmospheric inversions indicate that the year 2015 had a higher than usual northern land carbon uptake in boreal spring and summer, consistent with the positive greening anomaly and strong warming. This strong uptake was, however, followed by a larger source of CO2 in the autumn. For the year 2015, enhanced autumn carbon release clearly offset the extra uptake associated with greening during the summer. This finding leads us to speculate that a long-term greening trend may foster more uptakes during the growing season, but no large increase in annual carbon sequestration. For the tropics and Southern Hemisphere, a strong transition towards a large carbon source for the last 3 months of 2015 is discovered, concomitant with El Niño development. This transition of terrestrial tropical CO2 fluxes between two consecutive seasons is the largest ever found in the inversion records. The strong transition to a carbon source in the tropics with the peak of El Niño is consistent with historical observations, but the detailed mechanisms underlying such an extreme transition remain to be elucidated.
Potential influences of neglecting aerosol effects on the NCEP GFS precipitation forecast
Authors: Jiang Mengjiao , Feng Jinqin , Li Zhanqing , Sun Ruiyu , Hou Yu-Tai , Zhu Yuejian , Wan Bingcheng , Guo Jianping , Cribb Maureen
Published: November 2017

Abstract. Aerosol–cloud interactions (ACIs) have been widely recognized as a factor affecting precipitation. However, they have not been considered in the operational National Centers for Environmental Predictions Global Forecast System model. We evaluated the potential impact of neglecting ACI on the operational rainfall forecast using ground-based and satellite observations and model reanalysis. The Climate Prediction Center unified gauge-based precipitation analysis and the Modern-Era Retrospective analysis for Research and Applications Version 2 aerosol reanalysis were used to evaluate the forecast in three countries for the year 2015. The overestimation of light rain (47.84 %) and underestimation of heavier rain (31.83, 52.94, and 65.74 % for moderate rain, heavy rain, and very heavy rain, respectively) from the model are qualitatively consistent with the potential errors arising from not accounting for ACI, although other factors cannot be totally ruled out. The standard deviation of the forecast bias was significantly correlated with aerosol optical depth in Australia, the US, and China. To gain further insight, we chose the province of Fujian in China to pursue a more insightful investigation using a suite of variables from gauge-based observations of precipitation, visibility, water vapor, convective available potential energy (CAPE), and satellite datasets. Similar forecast biases were found: over-forecasted light rain and under-forecasted heavy rain. Long-term analyses revealed an increasing trend in heavy rain in summer and a decreasing trend in light rain in other seasons, accompanied by a decreasing trend in visibility, no trend in water vapor, and a slight increasing trend in summertime CAPE. More aerosols decreased cloud effective radii for cases where the liquid water path was greater than 100 g m−2. All findings are consistent with the effects of ACI, i.e., where aerosols inhibit the development of shallow liquid clouds and invigorate warm-base mixed-phase clouds (especially in summertime), which in turn affects precipitation. While we cannot establish rigorous causal relations based on the analyses presented in this study, the significant rainfall forecast bias seen in operational weather forecast model simulations warrants consideration in future model improvements.
Use of the Single Particle Soot Photometer (SP2) as a pre-filter for ice nucleation measurements: Effect of particle mixing state and determination of SP2 conditions to fully vaporize refractory black carbon
Authors: Schill Gregory P. , DeMott Paul J. , Levin Ezra J. T. , Kreidenweis Sonia M.
Published: November 2017

Abstract. Ice nucleation is a fundamental atmospheric process that impacts precipitation, cloud lifetimes, and climate. Challenges remain to identify and quantify the compositions and sources of ice nucleating particles (INPs). Assessment of the role of black carbon (BC) as an INP is particularly important due to its anthropogenic sources and abundance at upper tropospheric cloud levels. The role of BC as an INP, however, is unclear. This is, in part, driven by a lack of techniques that directly determine the contribution of refractory BC (rBC) to INP concentrations. One previously developed technique to measure this contribution uses the Single Particle Soot Photometer (SP2) as a pre-filter to an online ice nucleating particle counter. In this technique, rBC particles are selectively heated to their vaporization temperature in the SP2 cavity by a 1064-nm laser. From previous work, however, it is unclear under what SP2 conditions, if any, that the original rBC particles were fully vaporized. Furthermore, previous work also left questions about the effect of the SP2 laser on the ice nucleating properties of several INP proxies and their mixtures with rBC. To answer these questions, we sampled the exhaust of an SP2 with a Scanning Mobility Particle Sizer and a Continuous Flow Diffusion Chamber. Using Aquadag® as an rBC proxy, the effect of several SP2 instrument parameters on the size distribution and physical properties of particles in rBC SP2 exhaust were explored. We found that a high SP2 laser fluence [930 nW/(220-nm PSL)] is required to fully vaporize a ~ 0.76 fg rBC particle. We also found that the exhaust particle size distribution is minimally affected by the SP2 sheath-to-sample ratio; the size of the original rBC particle, however, greatly influences the size distribution of the SP2 exhaust. The effect of the SP2 laser on the ice nucleation efficiency of Snomax®, NX-illite, and Suwannee River Fulvic Acid was studied; these particles acted as proxies for biological, illite-rich mineral dust, and brown carbon INPs, respectively. The original size distribution and ice nucleation efficiency of all non-rBC proxies were unaffected by the SP2 laser. Furthermore, the ice nucleation efficiencies of all proxies were not affected when externally mixed with rBC. These proxies, however, always show a reduction in ice nucleating ability when internally mixed with rBC. We end this work with recommendations for users who wish to use the SP2 as a prefilter to remove large rBC particles from an aerosol stream.
How big is the influence of biogenic silicon pools on short-term changes in water-soluble silicon in soils? Implications from a study of a 10-year-old soil–plant system
Authors: Puppe Daniel , Höhn Axel , Kaczorek Danuta , Wanner Manfred , Wehrhan Marc , Sommer Michael
Published: November 2017

Abstract. The significance of biogenic silicon (BSi) pools as a key factor for the control of Si fluxes from terrestrial to aquatic ecosystems has been recognized for decades. However, while most research has been focused on phytogenic Si pools, knowledge of other BSi pools is still limited. We hypothesized that different BSi pools influence short-term changes in the water-soluble Si fraction in soils to different extents. To test our hypothesis we took plant (Calamagrostis epigejos, Phragmites australis) and soil samples in an artificial catchment in a post-mining landscape in the state of Brandenburg, Germany. We quantified phytogenic (phytoliths), protistic (diatom frustules and testate amoeba shells) and zoogenic (sponge spicules) Si pools as well as Tiron-extractable and water-soluble Si fractions in soils at the beginning (t0) and after 10 years (t10) of ecosystem development. As expected the results of Tiron extraction showed that there are no consistent changes in the amorphous Si pool at Chicken Creek (Hühnerwasser) as early as after 10 years. In contrast to t0 we found increased water-soluble Si and BSi pools at t10; thus we concluded that BSi pools are the main driver of short-term changes in water-soluble Si. However, because total BSi represents only small proportions of water-soluble Si at t0 (< 2 %) and t10 (2.8–4.3 %) we further concluded that smaller (< 5 µm) and/or fragile phytogenic Si structures have the biggest impact on short-term changes in water-soluble Si. In this context, extracted phytoliths (> 5 µm) only amounted to about 16 % of total Si contents of plant materials of C. epigejos and P. australis at t10; thus about 84 % of small-scale and/or fragile phytogenic Si is not quantified by the used phytolith extraction method. Analyses of small-scale and fragile phytogenic Si structures are urgently needed in future work as they seem to represent the biggest and most reactive Si pool in soils. Thus they are the most important drivers of Si cycling in terrestrial biogeosystems.
Evaluation of multiple forcing data sets for precipitation and shortwave radiation over major land areas of China
Authors: Yang Fan , Lu Hui , Yang Kun , He Jie , Wang Wei , Wright Jonathon S. , Li Chengwei , Han Menglei , Li Yishan
Published: November 2017

Abstract. Precipitation and shortwave radiation play important roles in climatic, hydrological and biogeochemical cycles. Several global and regional forcing data sets currently provide historical estimates of these two variables over China, including the Global Land Data Assimilation System (GLDAS), the China Meteorological Administration (CMA) Land Data Assimilation System (CLDAS) and the China Meteorological Forcing Dataset (CMFD). The CN05.1 precipitation data set, a gridded analysis based on CMA gauge observations, also provides high-resolution historical precipitation data for China. In this study, we present an intercomparison of precipitation and shortwave radiation data from CN05.1, CMFD, CLDAS and GLDAS during 2008–2014. We also validate all four data sets against independent ground station observations. All four forcing data sets capture the spatial distribution of precipitation over major land areas of China, although CLDAS indicates smaller annual-mean precipitation amounts than CN05.1, CMFD or GLDAS. Time series of precipitation anomalies are largely consistent among the data sets, except for a sudden decrease in CMFD after August 2014. All forcing data indicate greater temporal variations relative to the mean in dry regions than in wet regions. Validation against independent precipitation observations provided by the Ministry of Water Resources (MWR) in the middle and lower reaches of the Yangtze River indicates that CLDAS provides the most realistic estimates of spatiotemporal variability in precipitation in this region. CMFD also performs well with respect to annual mean precipitation, while GLDAS fails to accurately capture much of the spatiotemporal variability and CN05.1 contains significant high biases relative to the MWR observations. Estimates of shortwave radiation from CMFD are largely consistent with station observations, while CLDAS and GLDAS greatly overestimate shortwave radiation. All three forcing data sets capture the key features of the spatial distribution, but estimates from CLDAS and GLDAS are systematically higher than those from CMFD over most of mainland China. Based on our evaluation metrics, CLDAS slightly outperforms GLDAS. CLDAS is also closer than GLDAS to CMFD with respect to temporal variations in shortwave radiation anomalies, with substantial differences among the time series. Differences in temporal variations are especially pronounced south of 34° N. Our findings provide valuable guidance for a variety of stakeholders, including land-surface modelers and data providers.
Evolutionary GEM: The Evolution of the Primate Prehensile Tail
Authors: Xu Emily , Gray Patricia M.
Published: November 2017

The evolution of the prehensile tail illustrates the impact habitat can have on structural traits. Prehensile primates are able to support their entire body weight using only their tail, which opens up new feeding opportunities in their arboreal environments. This trait evolved separately in two families of New World monkeys. A transitional behaviour in its proposed evolutionary mechanism is tail-assisted hind limb suspension during locomotion in these dense forests. The evolution of more robust vertebrae, shorter distal vertebrae, a greater number of zygapophyseal joints, as well as larger and more convex articular surfaces, result in a stronger and more flexible tail. Prehensile tails have more expanded muscle attachments that can bear greater loading forces. A naked tactile pad that improves grip is present only in atelids. These differences in bone and muscle morphology make the prehensile tail more sturdy and dexterous, allowing prehensile primates to use their tails for an alternative function.
Examination of the Relation between Strategic Leadership Expectations and Organizational Justice: A Research on Health Sector
Authors: Yalçınsoy Ayhan , Aksoy Cenk
Published: November 2017

The aim of this study is to examine the relationship between strategic leadership and organizational justice within the healthcare sector. In the context of the study, the introduced model was tested by a questionnaire instrument with 41 items excluding demographic variables. A total of 320 completed questionnaires were used for analysis. Correlation, regression, T test and Anova analyzes were applied to the research data that obtained by the questionnaire. The study focused on the employees of hospitals in the Diyarbakir province of Turkey. The results suggest that there is a very strong positive linear relationship between strategic leadership and organizational justice variables. The result of the study is consistent with the results of previous research. Also, some disparities were observed among the demographic variables of the study.
POR QUE É MELHOR EM CASA? A PERCEPÇÃO DE USUÁRIOS E CUIDADORES DA ATENÇÃO DOMICILIAR
Authors: Silva Kênia Lara , Silva Yara Cardoso , Lage Érika Guimarães , Paiva Patrícia Alves , Dias Orlene Veloso
Published: November 2017

O objetivo deste estudo foi analisar as perspectivas dos usuários sobre os atendimentos de suas necessidades pelo serviço de atenção domiciliar. Trata-se de estudo qualitativo, com abordagem descritiva e exploratória. Participaram do estudo, usuários de serviços de atenção domiciliar de 16 municípios de Minas Gerais. Os dados foram obtidos de entrevistas com 20 usuários. Os resultados indicam que o perfil da população atendida pelos serviços remete a um público idoso. Os motivos de admissão são diversos e remetem à cronicidade. As equipes buscam realizar as atividades considerando as necessidades naturais e radicais de usuários. O atendimento no domicílio é apresentado como melhor, pelo conforto do lar, vínculo e pela superação quanto as barreiras de acesso a outros pontos da rede. Foi possível compreender que na perspectiva de usuários que o cuidar em casa apresenta novas relações que ampliam o acesso, a autonomia e a qualidade de vida do usuário.
RUÍDOS NA UNIDADE NEONATAL: IDENTIFICANDO O PROBLEMA E PROPONDO SOLUÇÕES
Authors: Jordão Márcia Maria , Costa Roberta , Santos Simone Vidal , Locks Melissa Orlandi Honório , Assuiti Luciana Ferreira Cardoso , De Lima Margarete Maria
Published: November 2017

Objetivou-se mensurar os ruídos e construir, junto com a equipe de enfermagem de uma unidade neonatal, estratégias para a redução dos níveis de ruídos produzidos no ambiente de trabalho. Pesquisa qualitativa, exploratório descritiva, realizada em outubro e novembro de 2016, em um hospital do sul do Brasil. Foi realizada a mensuração dos ruídos na unidade neonatal e rodas de conversa com 19 profissionais da enfermagem. Os dados foram analisados a partir da análise de conteúdo de Bardin, à luz da Política de atenção humanizada ao recém-nascido. O nível de ruídos variou de 53 a 75 decibéis e os participantes identificaram o ruído como um problema, apontando seus malefícios, levantando suas causas e propondo intervenções no ambiente e nas ações do profissional. Este estudo confirma que processos educativos promovem a transformação da realidade, garantindo o envolvimento da equipe na busca de soluções para o problema.
FATORES DE RISCO PARA ULCERAÇÃO NO PÉ DE INDIVÍDUOS COM DIABETES MELLITUS TIPO 2
Authors: Teston Elen Ferraz , Senteio Juliana De Souza , Ribeiro Beatriza Maria dos Santos Santiago , Maran Edilaine , Marcon Sonia Silva
Published: November 2017

Objetivou-se analisar os fatores associados ao risco de ulceração do pé em indivíduos com diabetes mellitus tipo 2. Estudo quantitativo, com 71 indivíduos numa Unidade Básica de Saúde de um município do estado do Paraná. Os dados foram coletados em entrevista domiciliar e com exame físico dos pés, no período de julho a setembro de 2016. O pé com risco à ulceração foi identificado em 35,2% da população estudada. Os fatores de risco às ulcerações mais prevalentes foram o corte inadequado das unhas, a utilização de calçados inadequados, presença de micose, calosidades, rachadura e pele ressecada. O enchimento capilar inadequado, a perda de sensibilidade e o histórico de úlceras estiveram associados ao risco de ulceração. Faz-se mister que os profissionais de saúde reconheçam e valorizem a importância do exame dos pés e do fornecimento de orientações teóricas e práticas, quanto aos cuidados necessários aos pés de indivíduos com diabetes.
Crop insurance demand in wheat production: focusing on yield gaps and asymmetric information
Authors: Castañeda-Vera Alba , Saa-Requejo Antonio , Mínguez Inés , Garrido Alberto
Published: November 2017

Analysis of yield gaps were conducted in the context of crop insurance and used to build an indicator of asymmetric information. The possible influence of asymmetric information in the decision of Spanish wheat producers to contract insurance was additionally evaluated. The analysis includes simulated yield using a validated crop model, CERES-Wheat previously selected among others, whose suitability to estimate actual risk when no historical data are available was assessed. Results suggest that the accuracy in setting the insured yield is decisive in farmers’ willingness to contract crop insurance under the wider coverage. Historical insurance data, when available, provide a more robust technical basis to evaluate and calibrate insurance parameters than simulated data, using crop models. Nevertheless, the use of crop models might be useful in designing new insurance packages when no historical data is available or to evaluate scenarios of expected changes. In that case, it is suggested that yield gaps be estimated and considered when using simulated attainable yields.
A method to evaluate the perceived ease of use of human-machine interface in agricultural tractors equipped with Continuously Variable Transmission (CVT)
Authors: Caffaro Federica , Bisaglia Carlo , Cutini Maurizio , Micheletti Cremasco Margherita , Cavallo Eugenio
Published: November 2017

At the end of the 20th century the adoption of the Continuously Variable Transmission (CVT) was one of the disruptive technological advances in agricultural tractors. Several changes in the Human Machine Interface (HMI) of the tractor cab have been introduced to accommodate this technology. HMIs are known to raise issues about their ease of use; however, this topic has been under-investigated in the agricultural sector. The present study introduces a method to investigate the perceived ease of use of the HMI of agricultural tractors equipped with technological innovations. The HMI required to manage a CVT tractor was evaluated by sixteen tractor drivers (8 novices and 8 experts). During the first contact with the machine and after having performed two targeted tasks with the tractor, participants filled in a questionnaire about the ease of use of the controls and of the touch-screen display, and evaluated the general perception of ease of use, safety, quality and solidity of the machine. The trial pointed out some significant differences between novices and experts, thus confirming the validity of the proposed method. In particular, novice users showed some difficulties when interacting for the first time with the HMI of the CVT tractor working station, whereas experts did not report similar difficulties. Thus, expertise seems to play a role in determining the quality of the interaction with the HMI. Training interventions should be designed to help novices in increasing their expertise effectively, avoiding effort and errors and improving user’s comfort and system performance.
Transient FV inhibitor of unknown origin in difficult clinical situation
Authors: Pointeau Odile , Marot Stéphane , Suhl Jaheyo , Goulenok Tiphaine , Pousset François , Zamy Michel , Mourad Jean-Jacques , Mazoyer Elisabeth , Jeune Sylvain Le
Published: November 2017

Acquired Factor V inhibitors are a rare condition, associated frequently with at times severe bleeding. Patients can show no symptoms and in exceptional cases thrombosis can be reported. In this article we report two cases of acquired FV inhibitors associated with thrombosis. We systematically reviewed the literature on FV inhibitors and thrombosis. A patient had acquired FV inhibitors and thrombosis. He had no bleeding and was treated with anticoagulant. Despite initial improvement, he died from legionaire’s disease. The second patient had septicemia, acquired FV inhibitors and deep vein thrombosis. The patient’s condition improved with anticoagulation and antibiotic therapy. Ten case reports were considered in the systematic review. The median age at admission was 67. Seven patients had bleeding episodes. The median peak inhibitor titer was 2.7 BU (0.62-8) while the median FV activity was 2% (1-75). Except for 2 patients, all recovered. FV has two activities: a procoagulant action activating prothrombin, as well as an anticoagulant action activating protein C. This property could be associated with thrombosis activity. Inhibitor could also have a through effect on activated protein C. In our study, because of underlying diseases, it was not possible to clearly demonstrate that inhibitors give thrombosis. Immunosuppressive therapies were administered in cases of severe bleeding. Heparin seemed efficient for thrombosis without major bleeding. The prognosis of acquired FV inhibitors appeared to be related to the underlying disease.
Transrectal ultrasound-guided prostate biopsies vs. magnetic resonance imaging ultrasound fusion targeted biopsies: Who are the best candidates?
Authors: Bey Elsa , Gaget Olivier , Descotes Jean-Luc , Franquet Quentin , Rambeaud Jean-Jacques , Long Jean-Alexandre , Fiard Gaelle
Published: November 2017

Introduction: The aim of this study was to compare the results of ultrasound-guided prostate biopsies (US-PB) and magnetic resonance imaging-ultrasound fusion biopsies (MRI-PB) in two contemporary cohorts and to describe the parameters orienting the choice of technique.Methods: Two contemporary cohorts of patients undergoing US-PB or MR-PB using the Urostation® (Koelis, Grenoble, France) between November 2010 and July 2015 were analyzed retrospectively. Patients with metastatic cancer or recurrence after treatment, saturation biopsies, and US-PB performed after a negative MRI were excluded. Comparison of populations, biopsy results, and clinical and biological parameters guiding the choice of technique were studied on multivariate analysis (logistic regression) taking into account the following confounding factors: age, prostate-specific antigen (PSA) rate, prostatic volume, number of previous biopsies, and abnormal digital rectal examination.Results: One hundred fourteen patients were included in the US-PB group and 118 in the MR-PB group. Prostate cancer was diagnosed among 65 patients in the US-PB group (detection rate 57.0%) and 70 patients in the MR-PB group (detection rate 59.3%) (odds ratio [OR] 3.00; 95% confidence interval [CI] 1.52–6.17; p=0.002). Among the cancers diagnosed in the MR-PB group, 21 were diagnosed by the two targeted biopsy cores only (15.5%). Patients undergoing MR-PB were significantly younger (p=0.0005), with a higher number of previous biopsy sessions (p<10-7) and larger prostate volume (p=0.001). PSA rate alone (p=0.23) and digital rectal examination (p=0.48) did not significantly interfere with the choice of a technique.Conclusions: Younger patients with larger prostates and prior negative biopsy were more likely to be offered the MR-PB technique. On multivariate analysis, the detection rate was higher in the MR-PB group.
Clinical outcomes of the sequential use of pazopanib followed by everolimus for the treatment of metastatic renal cell carcinoma: A multicentre study in Korea
Authors: Kim Jeong Ho , Lee Wan , Kim Tae Nam , Nam Jong Kil , Kim Tae Hyo , Lee Ki Soo
Published: November 2017

Introduction: The aim of this study was to investigate the real-world clinical outcomes of first-line pazopanib and second-line everolimus in Korean patients with metastatic renal cell carcinoma (mRCC).Methods: Data of patients who had mRCC with clear-cell component between 2001 and 2015 at multiple institutions were collected retrospectively. To be included in the analysis, patients had to meet the following criteria: age ≥18 years; received first-line targeted therapy with pazopanib; and received second-line targeted therapy with everolimus. The primary outcomes included overall survival (OS), progression-free survival (PFS), and adverse events (AEs).Result: A total of 36 patients were included in the analysis. The median followup period was 33.5 months (range 17‒49.5). The median PFS was eight months (95% confidence interval [CI] 6.4‒9.6) after treatment with pazopanib and three months (95% CI 1.9‒4.1) with everolimus. The median OS was 27 months (95% CI 16.6‒37.4). The median treatment duration was seven months (range 4.3‒10.8) after treatment with pazopanib and 3.5 months (range 3‒4) with everolimus. Multivariate analysis revealed that the Heng risk criteria were independently associated with OS (p<0.001). Almost every patient experienced some form of AE, the majority of which were mostly mild or moderate in severity. The most common AEs were diarrhea (50%), hypertension (44.4%), and fatigue (41.7%) after treatment with pazopanib, and anemia (47.2%), stomatitis (41.7%), and fatigue (38.9%) with everolimus.Conclusions: The outcomes for the patients treated with pazopanib followed by everolimus in Korea as observed by us were consistent with those reported by previous studies. The Heng risk criteria were significantly associated with the prognosis of patients with mRCC. AEs were mainly mild to moderate and readily managed.
Overall Survival in Stage III and IV High-Risk Head and Neck Squamous Cell Carcinoma Patients who received Adjuvant Chemotherapy and Radiation without Cisplatin
Authors: Iqbal Muhammad Fahair , Agamah Edem , Rao Krishna
Published: November 2017

Objectives: Microscopically involved resection margins and/or extracapsular spread represent the most significant prognostic factors for poor outcome in head and neck cancer. Purpose of this study was to estimate overall survival, and assess impact of demographic and clinicopathologic variables on survival in stage III and IV high-risk patients who received chemoradiation other than CisplatinMethods: Retrospective review Results: The final cohort of 18 eligible patients had a median age of 66 years and males were 66.66%. Median survival was 20.5 months. Patients were trichotomized into three age groups for comparison; ≤60 years, 61-70 years, ≥71 years. A superior overall survival was observed with advanced age (HR, 4.02; 95%CI, 1.33-12.17, p=0.016). Overall survival was significantly lower in patients with high Charlson comorbidity scores of 3-8 when compared to those with low scores of 0-2 (HR, 25.6; 95%CI, 2.78-236.7, p=0.0009). Young patients had high comorbidity scores (CCI > 2) based on the age-groups; ≤60 years (60%), 61-70 years (28.57%), ≥71 years (none). Tumor stage, positive resection margins, extracapsular spread, perineural involvement, lymphovascular invasion, tumor grade, high-risk human papillomavirus, body mass index, smoking and alcohol did not affect overall survival significantly.Conclusions: Young age and severe comorbidity should be considered when treating high-risk head and neck cancer squamous cell carcinoma patients with adjuvant chemoradiation therapy other than Cisplatin due to inferior overall survival.
Renewable Plasma Turbine System
Authors: Louis Rimon
Published: November 2017

The design of the new principle for creating electricity and increase the efficiency of both solar panels and wind power to be commercial source of energy for cities and manufacture depends on solar cells, gas turbine, compressor, magnets and electric generator to create plasma instead of fossil fuel. This paper presents the design of turbine depend on plasma from solar power to increase the efficiency of solar cells or wind turbines and the fuel considered as Plasma. The computational approach attempts to strike a reasonable balance to handle the needs of manufacture and cities. The principle of the solar reactor is approach to get clean, safe and cheap source of electricity in addition to contribute to solve the global warming problem in order to increase the investment and manufacture. Accordingly, in present study an attempt has been made through new device create hyper energy to generate electricity through the creation of direct electric current of the solar cells then interact electricity and compressed air to transform the gas into plasma to reach the ultimate goal to generate 1500 Megawatt from unlimited source of energy and with high assurance of clean and safety.
The Effectiveness of Multimedia Application on Students Listening Comprehension
Authors: Pangaribuan Tagor , Sinaga Andromeda , Sipayung Kammer Tuahman
Published: November 2017

Listening comprehension is a complex skill particulaly in mastered by non-native speaker settings. This researchaimed atfinding out the effect of multimedia application on students’ listening. The research design is experimental, with a t-test. The population is the sixth semester of HKBP Nommensen University at the academic year of 2016/2017, six classes of listening comprehension, 3 classes for experiemnts and the other for control, each class of 20 students. The findings states that the Tcount = 14.68 > Ttable = 2.02 in α significance 0.05 and degree of freedom 38. It means that, multimedia aplication is effective than conventinal media. Multimeadi in this study can be used by other lecturer or teacher as the optional instrument in teaching listening comprehension.
Effect of Psychological Ownership on Employee Silence and Task Performance: A Study on Academicians
Authors: Akcin Kultigin , Erat Serhat , Alniacik Umit , Ciftcioglu Aydem B.
Published: November 2017

This study examines the effect of psychological ownership on employee silence and task performance. It aims to probe the relationship between psychological ownership (a relatively new concept in the literature) and employee silence and the effect of psychological ownership on task performance. Research data is collected from 502 academicians employed by state universities in Turkey. Exploratory factor analyses, correlation and regression analyses are performed to test a number of hypotheses. Data analyses revealed that, there is a negative relationship between psychological ownership and both acquiescent silence and defensive silence, while there is a positive relationship between psychological ownership and pro-social silence. Further, it is found that acquiescent silence and defensive silence have significantly negative effects on task performance, while pro-social silence exerts a statistically significant positive effect on task performance. Finally, psychological ownership is found to exert a statistically significant positive effect on task performance. Research and managerial implications of these findings are discussed in detail.
Implications of low or high media use among parents for young children’s media use
Authors: Nikken Peter
Published: November 2017

Using an online questionnaire among 1,381 parents (children 0-7 years) in the Netherlands I investigated a) the congruence between the time that parents and children spend on various media; b) how several parent, child and household characteristics vary among four family types: low, moderate, high, and very high media consumers; and c) which characteristics most strongly differentiate these four family types. The analyses reveal that parents vary widely in their media consumption (from about 1 to more than 6½ hours media per day). Since the children’s media use parallels their parent’s, parents seem to provide an important example in the home. Data also show that lower and higher use families differ significantly on income, education level, number of devices at home, views on media for children, ease of applying co-active mediation and children’s proficiency in media use. Finally, the four family types can best be distinguished on the basis of quantity characteristics (education level, number of screens at home, time spent by children on media) and quality characteristics (type of media content used, ease of mediation, views on media for children). Consequences for young children’s development and parenting support are described.
The tacit dimension of parental mediation
Authors: Van Kruistum Claudia , Van Steensel Roel
Published: November 2017

Studies into the way parents mediate their children’s (digital) media use are challenging. A reason for this is that parents are not always aware of what they do and why, as their choices do not necessarily involve rational decision-making. In the present study we adopted the notion of “tacit knowledge” (Nonaka & Takeuchi, 1995; Polanyi, 1966) to explore how and why parents of young children mediate digital media use. In-depth interviews were conducted with 24 Dutch parents from 15 families who were selected to represent a range of socioeconomic backgrounds and different family compositions. Through qualitative analysis we first distinguished three mediation styles of “regulation”, “guidance” and “space”. Furthermore, we revealed seven values that drive parental mediation: three core values of “balance”, “freedom” and “protection” that are foundational in the sense that they explain why parents mediate; three orientational values of “qualification”, “Bildung” and “health/fitness” that explain to which end parents mediate; and one additional value of “flexibility” that accounts for parents’ exception-making. Finally, we showed that the most important emotions associated with these values were anger and disapproval (with balance and protection) and love and joy (with orientational values); fear was mentioned occasionally (in relation to protection).
Mediating social media use: Connecting parents’ mediation strategies and social media literacy
Authors: Daneels Rowan , Vanwynsberghe Hadewijch
Published: November 2017

Increasingly complex and multipurpose social media platforms require digital competences from parents and adolescents alike. While adolescents grow up with social media, parents have more difficulties with them, leading to uncertainties regarding their adolescents’ social media mediation. This study contributes to parental mediation research by (1) investigating whether mediation strategies defined by previous research are also relevant for social media use, and (2) exploring whether parents’ social media literacy is connected to the choice for a certain mediation strategy, as previous research already identified other impact factors such as children’s age or family composition. Using a qualitative research design, we interviewed 14 parents and 13 adolescents from 10 families in Belgium. Results indicate that, consistent with previous research, parents in this study mostly use active mediation focusing on risks and safety on social media. However, some parents monitor their children through social media accounts specifically set up for monitoring, or specialized mobile apps. Furthermore, parents with high (mostly critical) social media literacy choose active mediation over restrictive or technical strategies, recognizing opportunities of social media and letting adolescents explore on their own.
Uma Contribuição do Design Emocional para o Design de Superfície: um estudo de caso da ciclovia Van Gogh-Roosegaarde
Authors:   Universidade Federal do Rio Grande do Sul, Piffero Victoria de Menezes , Pizzato Gabriela Zubaran de Azevedo
Published: November 2017

O presente artigo aborda uma contribuição do Design Emocional para o Design de Superfície. A partir da teoria "Três Níveis de Design" proposta por Norman (2008), é conduzida uma análise da ciclovia Van Gogh-Roosegaarde, na Holanda. Os resultados apontam para o uso de materiais luminescentes como recurso interativo entre a superfície e o meio ambiente, além de causar impacto emocional aos usuários à medida que modifica a paisagem urbana de forma sustentável. O estudo demonstra os aspectos conceituais e os recursos técnicos que garantiram o sucesso do projeto. Além disso, concluiu-se que a tinta fosforescente empregada na obra foi fundamental para satisfazer aos três níveis de design, o que caracteriza um bom projeto.
Design de Superfície: proposição de método de ensino a partir de valores culturais brasileiros
Authors:   Universidade do Estado de Minas Gerais, Mol Iara Aguiar , Lana Sebastiana Luiza Bragança
Published: November 2017

O artigo trata da proposição de um método para o ensino do design, voltado para a criação de projetos de design de superfície, a partir da transposição de elementos e valores culturais presentes na identidade do território brasileiro. A apresentação dos resultados da experimentação com o método proposto evidencia a possibilidade de ampliação de ferramentas metodológicas para o desenvolvimento de projetos de design de superfície, com a consequente possibilidade de valorização de uma determinada cultura. Torna-se válida, dessa maneira, a proposição de união entre técnicas manuais e digitais aplicadas no processo criativo, embasadas em pesquisas de imersão e levantamento de informações a respeito de determinado objeto de estudo. Verificou-se que esse processo amplia a capacidade de aprendizado dos alunos, além de ampliar a percepção acerca dos valores culturais aliados a um território.
Produção científica em contabilidade gerencial: estudo bibliométrico em um congresso nacional de ciências contábeis
Authors:   Universidade de Brasília, Gomes Ana Karla de Lucena Justino , Soares Kalliny Régis ,   Universidade Federal da Paraíba
Published: November 2017

O objetivo deste artigo consiste em identificar as características das publicações efetuadas sobre Contabilidade Gerencial no Congresso USP entre os anos de 2010 a 2014. Uma apreciação dos artigos foi efetuada, com base no modelo de Lunkes, Feliu e Rosa (2012). A pesquisa é empírico-analítica, exploratória e utilizou-se de métodos estatísticos descritivos. Como principais resultados, verificam-se que as publicações em contabilidade gerencial correspondem a 23% do total, com diminuição gradativa nos cinco anos analisados. Tal resultado corrobora com pesquisas anteriores que sugerem sua perca de espaço na academia. Identificou-se crescimento da participação feminina como primeiro autor nos artigos analisados, bem como a utilização cada vez mais frequente de referências a periódicos internacionais, além da diminuição das citações oriundas de livros, evidenciando amadurecimento dos pesquisadores da área. Em contrapartida, observou-se idade média dos trabalhos referenciados considerável, 12 anos, sugerindo que os pesquisadores da área não estão concedendo a devida atenção aos novos achados, uma vez que, a contabilidade gerencial está em crescente e constante evolução. Como estratégias de pesquisa mais utilizadas encontram-se as pesquisas de levantamentos (33%) ou trabalhos documentais (30%). No que concerne à classificação em temas, verificou-se que as linhas de pesquisa mais abordadas são planejamento e controle, seguido de custos. Entre os temas mais frequentemente explorados estão: gestão estratégica, análise de indicadores e mensuração e avaliação de desempenho. Por fim, sugere-se que apesar das melhorias observadas, a contabilidade gerencial é uma área que necessita de uma clara personalidade para os estudos, bem como de aprofundamento metodológico.
Intersecções entre design thinkings e formação de professores
Authors:   Universidade Federal de Santa Catarina, Machado Andreia de Bem , Silva Andreza Regina Lopes da ,   Universidade Federal de Santa Catarina
Published: November 2017

A inovação é elemento integrado à sociedade contemporânea com novas metodologias no fazer pedagógico. A formação do docente amplia-se para uma visão integral do homem que promovendo novas metodologias para o ensino com intersecções de ferramentas diversas. Essas inovações metodoogicas fazem parte de um novo cenário educacional, onde o estudante é mais participativo e autonomo no seu pensar. Isso faz com que o professor procure por um novo fazer pedagógico inserindo nesse planejamento e problámticas que permitam com que o estudante motivesse a aprender. Esse faz com que a sala de aula torne-se um espaço de interação e de problematizações que tenha como pano de fundo as ferramentas do desinger thinking. Esse é utilizado para elaboração das aulas e também para oportunizar novas maneiras de ensinar ao estudantes dessa sociedade do conhecimento. Sendo assim, o objetivo nesse artigo é mapear as intersecções entre design thinking e a formação de professores. Para tanto se realizou uma busca sistemática seguida de uma análise bibliométrica na base de dados Scopus. Como resultado, identificou-se que a pesquisa emerge no campo das Ciências Socias intersectando as discussões na área de Engenharia; Ciência da Computação; Ciência ambiental; Artes e Humanidades; Negócios, Gestão e Contabilidade; Ciências da decisão e Medicina e congrega um novo olhar ao fazer pegagócio trazendo então uma discussão que transcenda a modelos cartezianos de ensinar onde aprendizagem se concebia em um processo passivo.
Hacia un modelo integrador de la tutoría en los diferentes niveles educativos
Authors: Álvarez González Manuel
Published: November 2017

El principal objetivo de este trabajo es presentar un modelo integrador de tutoría para los diferentes niveles educativos. Este se ha estructurado en dos grandes apartados: un primer apartado donde se desarrollan una serie de aspectos previos, que permitirán contextualizar la tutoría en el momento presente (la acción tutorial como un factor de calidad de la educación, las fortalezas y debilidades del modelo tutorial actual, la función docente y la función tutorial, los nuevos roles y
funciones de la acción tutorial y el marco conceptual de la tutoría); y en un segundo apartado se plantea el modelo integrador de la tutoría, destacando las razones que lo justifican, las características que lo definen, los objetivos y dimensiones a desarrollar, las estrategias de intervención y el modelo organizativo más adecuado para su puesta en práctica.
Abandono, rendimiento académico y tutoría: una investigación de la Universidad de Padua
Authors: Da Re Lorenza , Clerici Renata
Published: November 2017

La Universidad de Padua recientemente ha integrado, de forma experimental, a las tradicionales acciones de tutoría, un nuevo Programa de Tutoría Formativa, que pretende promover el éxito académico de los estudiantes y enfrentar los problemas relacionados con el abandono de los estudios, a través del fortalecimiento de algunas competencias trasversales que son  particularmente útiles para el curso de estudio específico. Con el fin de definir el perfil de los potenciales estudiantes usuarios del programa, detectar las características del abandono y del rendimiento en contextos específicos y, finalmente, evaluar el conocimiento y el uso de los servicios
de tutoría, se diseñó y llevó a cabo una encuesta web en una cohorte de 754 estudiantes
matriculados en el año académico 2012/13 en 3 grados elegidos como casos de estudio para la experimentación. En este artículo se presenta el instrumento y los indicadores utilizados para la recogida de información y algunos resultados que se consideran de particular interés para la
aplicación del Programa.
Un caso de tutoría grupal: aplicación de técnicas de aprendizaje cooperativo orientado a resolución de problemas de la especialidad en ingeniería ambiental
Authors: Araya Cabrera María Paz , Andrade Caroca Héctor Andrés , Cerqueira Pinto Joao Ricardo
Published: November 2017

En este artículo se analiza la tutoría grupal de un grupo-clase aplicando técnicas de aprendizaje cooperativo orientadas a la resolución de problemas en ingeniería ambiental, se realizará mediante la observación sistemática de clases (registro temporal de eventos y mapa de aula) en donde se evidenciará el grado de participación de los estudiantes y del docente en el aula y las interacciones de ambos. Igualmente también se aplicará una encuesta para conocer la percepción y grado
de satisfacción de los estudiantes con la metodología empleada y por último se efectuará una comparación de la tasa de aprobación de la asignatura en relación al año anterior para comprobar los efectos de la metodología activa en los resultados de aprendizaje. Los resultados han sido
satisfactorios, aumenta la participación en clase aunque otros deben reconsiderarse por desconocimiento del método empelado.