bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-actualisation and life-purpose orientations of students with different hierarchy of values
Authors: Bakushkin I. A. , Ilicheva I. M.
Published: March 2024

The article presents the results of exploring value and life-purpose orientations along with self-actualisation of studying youth. Two groups of students were identified according to the hierarchical structure of value orientations that have different features of life-purpose orientations and aspects of self-actualisation. The study was conducted on the basis of the State University of Social Sciences and Humanities. A large number of students of the humanities specialties participated in it. The analysis of values was performed with the methodology of value orientations proposed by M. Rokeach, the analysis of self-actualisation aspects – with a self-actualisation test suggested by L.Y. Gozman, M.V. Kroz and M.V. Latiskaya. The examination of life-purpose orientations was based on the test of life-purpose orientations developed by D. A. Leontiev. It was empirically proved that value orientations being a general meaningfulness of life are associated with its perception as a holistic process and with such features of self-actualisation as goals, beliefs, attitudes, and principles. Consequently, in the first group of students, behaviour and values depended on external evaluation and guidance, and due to the fact that attitudes to values are formed at a given time and in certain conditions, students being the subjects cannot control their life. The second group of students realises the phenomenon of self-actualisation as independence, the desire to follow their own values in life and behaviour, which are integrated into the personality structure, and the youth being the subjects can exercise this control.
The correlation between economic diversification and sustainable development of the Russian regions
Authors: Abramov R. A.
Published: March 2024

Diversity of economic activities and their diversification determine the key factors of sustainable development of the Russian regions. 

   The relevance of this study lies in the search of connection between the present economic process and such parameters of sustainable development as social well-being, economic and environmental stability.

   The research is based on examination of data of the Federal State Statistics Service, its publications, and other scien tific sources. The methodology includes a comprehensive analysis of economic indicators of diversification and their correlation with the three indices described above. The presented results demonstrate a direct connection between the level of economic diversification in the regions and their sustainable development. It is shown that regions with a more varied economic structure have higher indicators in the field of social stability, economic growth, and environmental safety. The authors determine that diversification as a whole does not depend on the production orientation or the traditional industrial equipment of a region. It is identified that innovative practices may be implemented in almost all subjects in case if a number of administrative barriers will be overcome. It is revealed that the level of sustainability of regional development directly depends on the degree of diversification of economic processes.
Features of state support of industrial enterprises under sanctions pressure
Authors: Grabovsky Ya. A.
Published: March 2024

The article discusses the problems of the current situation and development of the Russian industrial enterprises in the context of sanctions that were imposed against Russia in 2014 and significantly increased in 2022.

   The subject of study is the peculiarities of state support of the country’s industry: the conducted support policy, funding, sectoral priorities, and determination of the most important directions of this assistance.

   The article is devoted to issues of improving state policy based on the introduced restrictions. The author also considers the activities of the mainindustrial enterprises of the Russian Federation placed under sanctions and a decrease in their performance indicators.

   The purpose of the work is to study measures and principles of state support of industrial companies during the period of sanctions pressure.

   The research methodology includes the analysis of statistical data on the volume of industrial enterprises production over the past three years, comparison of indicators, as well as the study of various sources, articles, monographs on state support during the period of sanctions. The results obtained are generalising conclusions that during this complicated period competent state policy aimed at direct assistance to key enterprises in the country is of great importance.
The mechanism of concession agreements in the Russian heat supply system
Authors: Zakrevskaya A. G. , Lyubimova N. G. , Flaxman A. S.
Published: March 2024

The current research examines the mechanism of concession agreements, functioning in the sphere of heat supply, the ways of its conclusion, its advantages and differences from lease agreements. The effectiveness of the use of concessions is proved on the example of Voronezh and Perm energy companies. The renewal of the Russian heat supply system is, unfortunately, extremely slow. Despite the measures taken, the dynamics of equipment failures, accidents and heat losses have not yet been changed: their number is still gro wing. In a year, it is possible to update only half of the fixed assets from the need. The reasons for this are their sharp moral and physical ageing and lack of investors who would finance reconstruction, modernisation and erection of new heating system objects. The owners of the systems in many Russian regions are municipalities whose budget funds are insufficient to upgrade them. Mechanisms of public-private partnership (concession agreements are one of its manifestations) together with the “alternative boiler house” mo del should contribute to rectifying the situation. However, unconscientiousness of some investors, the failure to fulfill their obligations for construction and reconstruction of heat supply systems question the effectiveness of the mechanism and reduces them to lease agreements involving only operation of leased worn equipment. According to the research, the authors concluded that it is necessary to improve the discussed mechanism, monitor implementation of the agreements and strengthen administrative responsibility for non-compliance.
Influence of development factors of manufacturing industry on the economy of the North-Western Federal District
Authors: Shirokova E. Yu.
Published: March 2024

Due to constant tightening of the sanctions policy against Russia, the stable manufacturing industry is among fundamental factors of sustainability and active growth of the country’s economy. Since the beginning of 2022, sufficient efforts have been made to neutralise the negative consequences of foreign companies leaving the market and replace imported goods and technologies with domestic ones. An urgent issue is to assess importance of stable manufacturing industry for the economy of the country and its regions. For the industrially developed North-Western macroregion, which has been seriously affected by the disruption of relations with the European Union and the United States of America, the rapid restructuring and reorientation of commodity flows is an important task, alongside with the increase in production of high value-added goods based on the resources of the macroregion.

   The purpose of the study was to identify how much factors of development of the manufacturing industry influence gross regional product (hereinafter referred to as GRP) per capita in the North-Western Federal District (hereinafter referred to as NWFD).

   The constructed econometric model made it possible to assess the most serious factors, the increase of which will allow to influence the economy of the macroregion. It is proved that the average number of employees of small enterprises has the strongest positive impact on GRP per capita in the NWFD as its increase by 1 person leads to an increase in the resulting variable by 1,055.76 rubles, all other things being equal. Thus, currently, the activation of the manufacturing industry with more employees of small business will become a driver of recovery and sustainable development of the macroregion’s economy.
Lignin-based Mucin-mimicking Antiviral Hydrogels with Enzyme Stability and Tunable Porosity
Authors: Chandna Sanjam , L. Povolotsky Tatyana , Nie Chuanxiong , Wedepohl Stefanie , Quaas Elisa , Ludwig Kai , Boyakova Yulia , Bhatia Sumati , Meyer Klas , Falkenhagen Jana , Haag Rainer , Block Stephan
Published: March 2024

Mucus is a complex hydrogel acting as a defensive and protective barrier in various parts of the human body. The structure and composition of mucus play an important role in maintaining barrier properties by acting as a filter for the diffusion of biomolecules and pathogens. The rise in viral infections has underscored the importance of advancing research into mucus-mimicking hydrogels for the efficient design of antiviral agents. However, the performance of an antiviral strategy should not only be assessed based on its efficacy in inhibiting infections but also based on its sustainability. Herein, we demonstrate the gram-scale synthesis of biocompatible, lignin-based virus-binding inhibitors that reduce waste and ensure long-term availability. The lignin-based inhibitors were equipped with sulfate moieties, which are known binding partners for many viruses including SARS-CoV-2 and herpes viruses. In addition, crosslinking the synthesized inhibitors yielded hydrogels that mimicked native mucus with respect to surface functionality and rheology. It is found that the degree of sulfation has a very strong impact on the mesh size distribution of the hydrogels, which provides a new means to fine-tune steric and electrostatic contributions of the virus-hydrogel interaction. This feature strongly impacts the sequestration capability of the lignin-based hydrogels, which is demonstrated by infection inhibition assays involving human herpes simplex virus-1, influenza A viruses, and the bacterium Escherichia coli (E. coli). For HSV-1 and E. coli, these measurements showed a reduction in plaque (HSV-1) and colony-forming units (E. coli) by more than 4 orders of magnitude, indicating potent inhibition by the lignin-based hydrogels. Taken together, the sulfated lignin hydrogel is an excellent scaffold for large-scale synthesis of sustainable, biocompatible, and highly efficient pathogen-binding inhibitors.
PaStEL: Generator of Pathways with Structural Change on Pseudo Free-Energy Landscape from CryoEM Images
Authors: Tokuhisa Atsushi , Yamazaki Kimihiro , Wada Yuichiro , Wada Mutsuyo , Katoh Takashi , Nakagawa Akira , Akinaga Yoshinobu , Sasakura Yoko , Okuno Yasushi
Published: March 2024

Noisy cryoEM particle images reflect the conformational heterogeneity of biomolecules and have high potential for the study of biological process. As numerous simulation studies have shown, the study of biological process is attributed to the description of the free energy landscapes on the conformational pathways along with collective variable, which is usually difficult to define. In this study, we propose a methodology to automatically generate plausible conformational pathways via the theoretically isometric latent space trained by deep Auto-Encoder model using cryoEM experimental dataset directly. The proposed method of the PaStEL can speedily show structural change on the plausible conformational pathways along with free energy landscape. Solid theoretical guarantees and tests using synthetic cryoEM data have succeeded in obtaining qualitatively correct energy landscapes on the generated plausible pathways. Furthermore, benchmarking with real cryoEM experimental data of 50S Ribosome has successfully demonstrated that the conformational changes with energy landscapes consistent with existing studies without any manual labor. Finally, the PaStEL was applied to spike proteins of SARS-CoV-2 and successfully characterized the difference in the conformational changes between the wild type and the mutant (D614G) focusing on the Receptor Binding Domain regions.
Development and characterization of amino donor-acceptor Stenhouse adducts
Authors: Reyes Cesar , Lee Hye Joon , Karanovic Connie , Picazo Elias
Published: March 2024

Donor-acceptor Stenhouse adducts (DASAs) are molecular photoswitches that have spurred a decade of interest because of their dynamic photophysical properties, complex photoswitching mechanism, and diverse applications. Despite breakthroughs in modularity for the donor, acceptor, and triene compartments, the backbone heteroatom has remained static due to synthetic challenges. We provide a predictive tool and sought-after strategy to vary the heteroatom, develop a new subclass of DASA photoswitches, and analyze backbone heteroatom effects on photophysical properties. Amino DASA synthesis is enabled by the first aza-Piancatelli rearrangements on pyrrole substrates, imparting an aromaticity-breaking rearrangement that capitalizes on nitrogen’s additional bonding orbital and the inductive properties of sulfonyl groups. Amino DASA structure was confirmed by single crystal X-ray diffraction, the photochromic properties were characterized, and the photoswitch isomerization was investigated. Complimentary to other DASA compartments, this study furthers our insight into the structure-property relationship of this complex photoswitch and brings DASAs closer to application-specific design.
Extended sulfo-pillar[6]arenes – a new host family and its application in the binding of direct oral anticoagulants
Authors: Wilson Chelsea R. , Puckett Austia O. , Oliver Allen G. , Hof Fraser
Published: March 2024

Herein we report the synthesis of extended sulfo-pillar[6]arenes, a new supramolecular host class with a pedigree in salt tolerance and ultra-high binding affinity towards multiple drug classes. The parent sulfo-pillar[6]arene (sP6) is a high affinity host with the potential to act as a supramolecular reversal agent. However, it lacks synthetic diversification of the core scaffold. The new extended sulfo-pillar[6]arenes have either a mono-directional (A1sP6) or bi-directional (A1A2sP6) extension of the hydrophobic cavity. This new functionality enables more non-covalent interactions and strong affinity towards guests, which we demonstrate using the direct oral anticoagulants (DOACs) dabigatran, betrixaban, and edoxaban. DOACs are highly prescribed therapeutics that are underexplored in host-guest chemistry. These agents prevent the formation of blood clots and reversing their action during emergencies is paramount. We show that the new hosts have ultra-high affinity to-wards dabigatran (Kd = 27 nM, A1A2sP6) in salty solutions. Their increased functionality resulted in a 6- and 2.5-fold in-crease in affinity towards betrixaban (Kd = 230 nM, A1A2sP6) and edoxaban (Kd = 800 nM, A1sP6), relative to the unfunctionalized sulfo-pillar[6]arene.
Hydrodynamic Dual Space Yields a Prediction of the Muon Magnetic Moment Anomaly with Better Accuracy than the Standard Model
Authors: Hawkins Adam
Published: March 2024

Despite their foundations in classical mechanics, hydrodynamic models have experienced a resurgence in modern physics, particularly in the context of electron-phonon interactions. These “tantalizing parallels1” between modern physics and hydrodynamics have not, however, seen a similar resurgence in the context of atomic theory. Here, a hydrodynamic dual space is investigated as a model for electron-photon interactions across orbital transitions. A diffusive equation is derived from dimensional analysis of a solid body of arbitrary shape displacing an unspecified, fluid-like matrix. The frictional energy dissipated across the solid-fluid interface is then treated as an equivalent to electromagnetic energy (i.e., photons). This relationship is shown to correspond to the Planck-Einstein relation and suggests a hidden diffusive variable within the Planck constant with units of m2/s. An experimental value of this apparent constant is determined and the resulting value is used to predict a theoretical value of the muon magnetic moment anomaly. The accuracy of the resulting prediction is within 0.04 sigma of the most recent experimental value and is an improvement over the 5.2 sigma predicted via the standard model of particle physics.
A Review of COVID-19 Mathematical Models and an Implementation of Vaccination Policies
Authors: Gouin Samir , Li Amy , Hanxi Ma Gloria , Yang Dimitri
Published: March 2024

Cellular automata (CA) models have been used to simulate the behaviour of infectious diseases and can offer valuable information concerning the spread of infection and population susceptibility to sickness. Furthermore, CA models can be used to evaluate various response strategies, such as herd immunization and vaccination. By assessing CA approaches for COVID-19, we identified a lack of an age-based symptom severity score and death probability (1-3). We used a Susceptible Infected Removed (SIR) model and distribution of population age groups from the Canadian government to determine the effect of vaccinating older (60+ years old) versus a younger population (30-59 years old). Our findings show a significant decrease in the total number of deaths and peak number of infections when the older population was vaccinated. This is a result of the higher probabilities of death and severe symptoms in older age groups. While this simulation is based on a small scale, the findings provide evidence to prioritize vaccination of the elderly.
The Ethical Implications of Student Participation in Short-Term Experiences in Global Health
Authors: Bansal Rishi , McKibbin Corey
Published: March 2024

Student interest in short-term experiences in global health (STEGHs) has grown in recent years. Typically, students travel from high-income countries (HIC), standing to benefit from varied clinical exposure and participation beyond what is allowed in their home jurisdictions. Whether STEGHs benefit the hosting low- and middle-income countries (LMICs) are less clear. We seek to mitigate the ethical implications of student participation in STEGHs by examining three domains: (a) the medical scope of practice for students; (b) cultural competency; and (c) reciprocal partnerships. These domains permit further elucidation of key issues relating to ethics, and public policy, to clarify how STEGH initiatives can be evaluated. Our analysis implicates that STEGHs can be described as post-colonial enterprises that perpetuate structural violence in LMICs and may cultivate hubris and savior complexes in learners. Examination of these domains necessitates two points for further analysis and evaluation with respect to STEGHs: (1) a stronger idea of justice and distributive justice that includes considerations of structural violence and reciprocity; and (2) realignment of student global health priorities towards the communities being cared for as opposed to the benefits of high income countries and volunteers. To improve global health knowledge transfer worldwide, we advocate for reciprocity between HIC and LMIC institutions and training in the colonial history of global health. We hope these changes will reduce eurocentrism within student global healthand any potential harms.
Comparison of waterbird communities in a Mediterranean salina – saltmarsh complex
Authors: Birtsas Periklis K. , Sokos Christos K. , Papaspyropoulos Konstantinos G. , Kazoglou Yannis E.
Published: March 2024

Coastal wetlands provide habitat for large numbers and many species of waterbirds. Man-made salinas are a particu-lar habitat type often found in such wetlands. This study is an initiative to understand the differences in bird communities between a salina (including evaporation ponds and prebasin) and a saltmarsh. Bird counts and nest surveys took place in the wetlands of Angelochori, Thessaloniki, Greece, in 1991, when the salina was inactive, and in 1997, 2000-01 when it was active. Counts in evaporation ponds were richer in species, abundance and nests compared to the prebasin and the saltmarsh. These three wetland types supported different bird communities. Similarities among bird communities depended on the inundation of the salina with seawater. Evaporation ponds in their inactive period presented low similarity with the communities of the prebasin and the saltmarsh ; in the active period this was observed only for the saltmarsh. Species showing clear selection for the evaporation ponds were Charadrius alexandrinus, Calidris alpina, Calidris minuta, Recurvirostra avosetta, Sterna hirundo, Sternula albifrons, Sterna sandvicensis and Haematopus ostralegus; the prebasin was preferred by Phoenicopterus roseus and Anas platyrhynchos, and the saltmarsh by Anas querquedula, Anas clypeata, Plegadis falcinellus, Tringa totanus, Tringa glareola, Tringa stagnatilis and Himantopus himantopus.
The Development of Mass media in International Relations: In case of Al-Jazeera Effects in Middle East
Authors: Prakoso Muhammad Pambudi
Published: March 2024

The international network has a very important role in strengthening the solidarity and unity of the masses, in spreading information to the community by creating virtual communities. Al-Jazeera as one of the most reputable media outlets in the international arena and have considerable influence in society. They have a vital role in raising  awareness to the people in case of  religion, culture and issues in the world. In addition, more rapid and accessible information in the global media has been supported by information among countries that have changed the politics of the authorities. mass media in international relations that grow so fast recently by knowing that the media and politics are  related each others with sharing the mutual benefit to each other. The author discusses Al- Jazeera achievements  in changing and growing people's opinions on politics, the media as a vehicle for community empowerment, and more. By producing new concepts through information and news that raise awareness of the Middle East community, the region's unequal social and political conditions, and the Middle East's position. In the Middle East, things are changing, and people are becoming more aware of the value of freedom and democracy.
Keywords : Development; Mass Media; Al-Jazeera; Effect
The Trends of Legal Migration: Reasons of Indonesian Legal Migrants Settling in the Netherlands
Authors: Wasisto Nada Gavrila , Pilongo Levina Charisa , Satya Putu Agung Nara Indra Prima
Published: March 2024

Indonesia has been one of the contributing countries in sending migrants to the Netherlands. The historical relations along with the large economic opportunities in the Netherlands play a part in the promotion of cross-border movement for Indonesians to the Netherlands. However, those are only one of many underlying reasons why Indonesians are willing to leave their home country to a more developed country. This article questions the reasons behind Indonesian legal migration in the Netherlands and looks into the trend of Indonesian migrants as the result of the fulfilment of human development embedded in education and employment policies and management in the Netherlands. The relationship between the two aspects and the Indonesian migration in the Netherlands is examined through the Theory of Human Development by Amartya Sen, specifically in regard to the improvement of human capabilities and freedom of choice. The authors found that a country that promotes human development is more favourable to live in. Thus, in this case, the education and employment policies and mechanisms of the Netherlands that are focusing on the fulfilment of freedom of choice and the improvement of human capabilities attract international migrants, particularly the Indonesians.
 
Keywords: the Netherlands; Indonesia; Legal Migrants; Migration
Pengembangan LKPD berbasis Android Untuk Mata Pelajaran Sejarah Kelas XII
Authors: FIKRI ASYRUL
Published: March 2024

LKPD can help prepare students for school exams or daily tests. The focus of development is on history subjects for class XII (twelve) students. The LKPD contains material and practice questions. The method used in this research is a research and development method using a software development approach in this case is android-based software. The development of android-based LKPD for History Subject Class XII uses the ADDIE model, namely Analysis (analysis), Design (design), Development (development), Implementation (implementation), and Evaluation (evaluation). The data analysis technique used in this research is descriptive analysis, namely by calculating the percentage value of the validation results. The results of the research and discussion are; The assessment from material experts regarding android-based LKPD for Class XII History Subjects obtained an average value of all indicators of 4.20. Based on this assessment, the teaching materials are declared Eligible to use; Assessments from media experts regarding android-based LKPD for Class XII History Subjects obtained an average score of 4.5 in the "Very Eligible" category; and the trial was conducted at SMAN 1 Rumbio Jaya in class XII with 30 students. Students' assessment of the Android-based LKPD obtained an average value of all indicators of 4.0. Based on these data, the Android-based LKPD was declared "Eligible" to use.
PERANAN TENGKU SAID NOERDIN DALAM MEMPERTAHANKAN KEMERDEKAAN DI PELALAWAN (1945-1950)
Authors: Sofindra Viola Enjela , Bunari Bunari , Fikri Asyrul
Published: March 2024

Abstrak: Tengku Said Noerdin merupakan salah satu tokoh di bidang militer yang bertugas dalam mempertahankan kemerdekaan Republik Indonesia di Pelalawan (1945-1950). Tengku Said Noerdin lahir di Pelalawan pada tanggal 10 Agustus 1921 dari orang tua yang bernama Tengku Said Oesman dan Tengku Syarifah Khatijah. Tengku Said Noerdin adalah anak kedua dari enam bersaudara yang memiliki peran dalam mempertahankan kemerdekaan di Pelalawan (1945-1950). Penelitian ini bertujuan (1) untuk mengetahui latar belakang kehidupan Tengku Said Noerdin, (2) untuk mengetahui peranan Tengku Said Noerdin dalam mempertahankan kemerdekaan di Pelalawan (1945-1950), (3) untuk mengetahui akhir perjuangan Tengku Said Noerdin dalam mempertahankan kemerdekaan di Pelalawan (1945-1950). Dalam penelitian ini penulis menggunakan metode Kualitatif. Data dikumpulkan melalui metode wawancara, observasi, dan dokumentasi. Analisis data menggunakan 4 komponen analisis yaitu penyusunan data, klasifikasi data, pengelolahan data, dan menganalisis serta menyimpulkan hasilnya. Hasil dari penelitian ini adalah peranan Tengku Said Noerdin dalam mempertahankan kemerdekaan di Pelalawan yang pada awalnya hanya anak keturunan raja kerajaan Pelalawan yang bercita cita untuk menjadi seorang tentara dan akhirnya bisa menjadi kurir informasi untuk kemerdekaan Indonesia   ke Pelalawaan menuntunnya untuk menjadi Tentara Keamanan Rakyat atau TKR hingga ditunjuk oleh Hasan Basri untuk mengikuti sekolah di Resimen IV setelah Tengku Said Noerdin Menyelesaikan sekolahnya di Resimen IV Tengku Said Noerdin pun dipercaya untuk memegang kompi KPG IV Pelalawan sebagai Komandan Sektor pada saat itu. Pada 1 September 1977 Tengku Said Noerdin resmi diberikan hak pensiunnya beliau juga bergabung sebagai anggota Dewan Paripurna Daerah Legiun Veteran Republik Indonesia.
Sejarah Perkembangan Sekolah Menengah Kejuruan Muhammadiyah 3 Terpadu Pekanbaru
Authors: Kholil Nurda
Published: March 2024

Abstrak : Skripsi ini berjudul Sejarah Perkembangan Sekolah Menengah Kejuruan Muhammadiyah 3 Terpadu Pekanbaru 2003-2019 . Adapun tujuan dari penelitian ini adalah untuk mengetahui : (1) bagaimana sejarah berdirinya SMK Muhammadiyah 3 Terpadu Pekanbaru. (2) bagaimana perkembangan SMK Muhammadiyah 3 Terpadu Pekanbaru pada tahun 2003-2019. (3) apa faktor pendorong dan faktor penghambat SMK Muhammadiyah 3 Terpadu Pekanbaru pada tahun 2003-2019. Penelitian ini menggunaan pendekatan historis, metode pengumpulan data dengan kajian lapangan berupa dokumentasi dan wawancara serta studi arsip dan pustaka. Penelitian ini dilaksanakan di SMK Muhammadiyah 3 Terpadu Pekanbaru. Setelah data di kumpulkan, pengujian data dilakukan dengan kritik sumber yaitu dengan menguji keaslian sumber dan membandingkan antara data yang satu dengan yang lain, seperti membandingkan hasil wawancara dengan bukti tertulis. Berdasarkan hasil penelitian ini disimpulkan bahwa pada awal berdirinya SMK Muhammadiyah 3 Terpadu Pekanbaru merupakan   SMK Muhammadiyah 1 Kampus 2 Panam-Pekanbaru, yang mulai beroperasi pada tahun 2003, dengan membuka 2 jurusan, yaitu: (1) Jurusan Teknik Mekanik Otomotif. (2) Jurusan Teknik Elektronika. pada tahun pelajaran 2008/2009 dibukalah jurusan Teknik Informatika.   Kemudian pada tahun 2010 diurus cikal bakal pendirian SMK Muhammadiyah 1 kampus 2 Panam menjadi SMK Muhammadiyah 3 Terpadu Pekanbaru. Hasil penelitian ini yaitu, (1) SMK Muhammadiyah 3 Terpadu Pekanbaru berdiri pada tahun 2003 sebagai sekolah kampus jauh dari SMK Muhammadiyah 1 Pekanbaru yang terletak di pasar bawah (2) SMK Muhammadiyah 3 Terpadu mengalami perkembangan yang cukup pesat beberapa tahun, pada beberapa aspek seperti bangunan dan sarana prasarana, namun mengalami pasang surut pada aspek jumlah pelajar. (3) faktor pendukung SMK Muhammadiyah 3 Terpadu Pekanbaru adalah peran dan semangat para pendiri serta guru, dan mendapat dukungan dari masyarakat dan juga pemerintah sewaktu awal pertumbuhan SMK Muhammadiyah 3 Terpadu pekanbaru. Faktor yang menjadi penghambat SMK Muhammadiyah 3 Terpadu Pekanbaru adalah keterbatasan guru, ruangan dan gedung pembelajaran di masa-masa awal perintisan.  

  
agrarianisasi dan Konflik Agraria Mengubah Sosial Budaya Masyarakat Pedesaan
Authors: Putra Arvian Messianik
Published: March 2024

Seiring dengan peningkatan populasi dan perkembangan struktur ekonomi, kebutuhan lahan kegiatan non pertanian cenderung meningkat. Kecenderungan Hal ini membuat konversi lahan pertanian sulit dihindari lahan pertanian adalah karena pembangunan perumahan meningkat setiap tahun. Hal ini lah yang membuat sawah dipindahkan berfungsi sebagai bangunan. Penelitian ini bertujuan mengetahui apakah deagrarianisasi dan konflik graria mengubah sosial budaya masyarakat pedesaan. Artikel ini ditulis menggunakan metode studi literatur. Hasil penelitian adalah deagrarianisasi dan konflik graria memang mengubah sosial budaya masyarakat pedesaan
ANALISIS PENGARUH SITUASIONAL KERJA DAN KOMPETENSI TERHADAP EFEKTIVITAS KERJA PEGAWAI PADA KANTOR BUPATI KABUPATEN PIDIE
Authors: Akmal Syamsul
Published: March 2024

Penelitian ini berjudul Analisis Pengaruh Situasional Kerja dan Kompetensi terhadap Efektivitas Kerja Pegawai pada Kantor Bupati Kabupaten Pidie. Penelitian bertujuan untuk mengetahui pengaruh situasional kerja dan kompetensi terhadap efektifitas kerja pegawai di kantor Bupati Kabupaten Pidie serta untuk mengetahui variabel dominan yang berpengaruh terhadap efektivitas kerja pegawai di kantor Bupati Kabupaten Pidie. Penelitian ini dilaksanakan pada kantor Bupati Kabupaten Pidie yang terletak di Jalan Prof Moh. Ibrahim, Sigli, Kabupaten Pidie. Populasi penelitian ini adalah seluruh pegawai kantor Bupati Kabupaten Pidie yaitu 144 orang pegawai, kemudian diambil sampel sebanyak 50% dari populasi atau 72 orang pegawai. Metode pengumpulan data dilakukan melalui kepustakaan dan penelitian lapangan.   Teknik pengumpulan data terdiri dari wawancara dan kuesioner. Dalam menjelaskan hubungan antara variabel independen dengan dependen, model yang digunakan adalah model regresi berganda, yang dapat dinyatakan sebagai berikut :   Å¶ = a + b1X1+ b2X2 + e. Berdasarkan output SPSS diperoleh model regresi berganda dalam bentuk persamaan sebagai berikut: Y =   4.807+ 0.258X1+ 0.180X2.   Variabel Situasional Kerja (X1) mempunyai pengaruh yang paling dominan terhadap Efektivitas Kerja Pegawai Kantor Bupati Kabupaten Pidie. Secara simultan diperoleh nilai Fhitung9.823 > Ftabel3.773, menunjukkan bahwa variabel Situasional Kerja (X1) dan Kompetensi (X2) secara bersama-sama berpengaruh secara signifikan terhadap Efektivitas Kerja Pegawai Kantor Bupati Kabupaten Pidie. Variabel Situasional Kerja (X1) diperoleh nilai thitung 2.731 > ttabel 1.994, artinya bahwa variabel Situasional Kerja (X1) secara parsial berpengaruh signifikan terhadap efektivitas kerja pegawai pada Kantor Bupati Kabupaten Pidie. Variabel Kompetensi (X2) diperoleh nilai thitung 2.778 > ttabel 1.994, dengan demikian variabel Kompetensi secara parsial berpengaruh signifikan terhadap Efektivitas Kerja Pegawai pada Kantor Bupati Kabupaten Pidie. Indeks determinasi masing-masing variabel Situasional Kerja (X1) dan Kompetensi (X2) terhadap variabel Efektivitas kerja   Pegawai (Y) diperoleh sebesar 22.2% yang berarti bahwa varisi variabel bebas dapat menjelaskan variabel tidak bebas sebesar 22.2% sedangkan selebihnya yaitu 77.8% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
Nilai Budaya Kahua di Negeri Saleman Kabupaten Maluku Tengah untuk Pendidikan Karakter
Authors: Akohilo Sarban
Published: March 2024

Pembinaan karakter masyarakat melalui budaya lokal Kahua memiliki manfaat ganda yang mana selain masyarakat Saleman memahami nilainya, juga dapat menerapkan nilai-nilai yang terkandung dalam budaya tersebut. Penelitian ini bertujuan untuk mendeskripsikan nilai budaya Kahua di negeri Saleman, Kecamatan Seram Utara Barat, Kabupaten Maluku Tengah. Metode yang digunakan adalah penelitian deskriptif kualitatif. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi. Hasil yang ditemukan dalam penelitian ini berupa lima nilai budaya Kahua, yaitu hakekat hidup manusia, hakekat karya manusia, hakekat waktu manusia; hakekat alam manusia, dan hakekat hubungan antar manusia. Karakter dari budaya Kahua adalah mandiri, tanggung jawab, menghargai prestasi, kerjakeras, peduli lingkungan, demokratis, bersahabat, dan toleransi.
Alturisme Masyarakat Kota (Studi Kebijakan Pemerintah Daerah Dalam Mengatasi Pengemis Di Kota Bandar Lampung)
Authors: Reswari Annisa , Mutaharoh Aulia Wazulfa , Triono Agus
Published: March 2024

Penelitian ini bertujuan untuk mendeskripsikan bagaimana mengatasi pengemis di Kota Bandar Lampung yang mengalami peningkatan secara signifikan dan faktor-faktor apa saja yang menjadi penyebab semakin maraknya pengemis di Kota Tapis Berseri ini. Karena salah satu tugas utama suatu negara adalah memberikan kesejahteraan bagi rakyatnya. Hal serupa juga berlaku bagi Indonesia yang menganut konsep hukum kesejahteraan. Terlebih lagi dalam konstitusi negara ini ditegaskan bahwa fakir miskin dan anak-anak terlantar dipelihara oleh negara. Namun, dalam praktiknya, masih dijumpai fenomena yang mengindikasikan belum sejahteranya rakyat Indonesia, salah satunya adalah semakin maraknya pengemis.

Penelitian ini menggunakan metode penelitian normatif yang didasarkan pada Peraturan Daerah Kota Bandar Lampung No. 03 Tahun 2010 tentang Pembinaan Anak Jalanan, Gelandangan, dan Pengemis, ajaran agama Islam, serta aturan adat yang menjadi pedoman bagi masyarakat Lampung, yaitu Piil Pesenggiri. Subjek penelitian ini adalah masyarakat Kota Bandar Lampung dan lebih difokuskan kepada masyarakat yang ada di tempat-tempat umum. Hasil penelitian menunjukkan bahwa peraturan yang ada sudah diterapkan namun banyak masyarakat yang belum mengetahui atau enggan untuk patuh dengan peraturan tersebut. Selain itu, masyarakat yang menjadi pengemis adalah orang-orang Islam yang notabennya menggunakan atribut Islam dalam melakukan kegiatan tersebut.

Dengan demikian, perlu adanya kerjasama antara pemerintah dengan stakeholders terkait untuk memaksimalkan implementasi Perda yang ada. Selain itu, Dinas Sosial juga sangat dibutuhkan sebagai sarana untuk menampung para pengemis dan tempat untuk mengasah keterampilan para pengemis. Dengan adanya kerjasama tersebut, diharapkan perda yang ada dapat berjalan dengan maksimal dan angka pengemis dapat menurun.
Strategi Program CHSE Agrowisata Tlogo Tuntang Menggunakan Metode POST
Authors: Kristiansen Herman Novry
Published: March 2024

Pariwisata Indonesia yang terdampak oleh pandemi Covid-19 menyebabkan minat kunjungan wisatawan ke daya tarik wisata ataupun hotel menjadi berkurang. Alasan utama adalah masalah kesehatan. Tingkat kepercayaan wisatawan terhadap pengelola usaha jasa pariwisata semakin menurun karena perasaan khawatir akan jaminan keamanan khususnya masalah kesehatan. Penelitian ini membahas tentang analisis penerapan Cleanliness, Health, Safety, Dan Environment Sustainability (CHSE) yang telah dilakukan oleh Agrowisata Tlogo Tuntang dan pengaruh yang diberikan terhadap kunjungan wisatawan. Tujuan penelitian adalah untuk mengetahui penerapan CHSE telah memberikan jaminan kenyamanan terhadap tamu yang datang berkunjung, sehingga dapat meningkatkan tingkat kunjungan ke Agrowisata Tlogo Tuntang. Penelitian ini merupakan jenis penelitian lapangan (field research) dengan menggunakan pendekatan kuantitatif. Data diperoleh dari wisatawan yang berkunjung sebagai responden
Penanaman Sikap Sosial Melalui Pembelajaran IPS di Kelas VII MTsN 1 Mukomuko
Authors: Suci Nurhariani , Suci Nurhariani
Published: March 2024

Penelitian ini bertujuan untuk mendeskripsikan tentang: (1) peran guru dalam menanamkan sikap sosial siswa di kelas VII MTsN 1 Mukomuko, (2) faktor pendorong dan penghambat bagi guru dalam menanamkan sikap sosial siswa di kelas VII MTsN 1 Mukomuko. Penelitian ini merupakan penelitian kualitatif deskriptif penanaman sikap sosial siswa di kelas VII MTsN 1 Mukomuko melalui pembelajaran IPS yang dikumpulkan melalui observasi dan wawancara serta dokumentasi. Analisis data yang digunakan adalah Model Miles dan Huberman yang terdiri dari pengumpulan data, reduksi data, display data dan penarikan kesimpulan atau verifikasi. Hasil penelitian menunjukkan bahwa: (1) sikap sosial siswa kelas VII MTsN 1 Mukomuko ditanamkan melalui pembelajaran IPS dengan cara menanamkan nilai-nilai sikap sosial siswa dengan strategi pembelajaran IPS, kemampuan guru memberikan contoh sikap interaksi yang baik kepada siswa baik di dalam kelas maupun di luar kelas, mengkaitkan materi pelajaran IPS dengan nilai-nilai sikap sosial dan dengan memberikan kalimat-kalimat positif yang mengandung nilai sikap sosial diawal pembelajaran, menggunakan media IT pembelajaran IPS, dan melakukan evaluasi terkait sikapsosial. (2) Hasil penanaman sikap-sikap sosial siswa kelas VII MTsN 1 Mukomuko melalui pembelajaran IPS sudah tertanam dengan kategori Baik. Guru terlihat sudah berhasil menanamkan nilai sikap sosial sesuai dengan indikator-indikator yang telah peneliti jabarkan, yaitu: kejujuran, sopan santun, disiplin diri, toleransi pada siswa kelas VII MTsN 1 Mukomuko.

 
Greener approaches to improve phenolic acid composition and antioxidant
activity of different cultivation methods of Zingiber officinale Roscoe extracts
Authors: A. Nur Diyana , S.N. Nor Azlan , M.I. Mohd Lazim , Hussin A. , Mansor A. , Ibrahim A.H.
Published: March 2024

Zingiber officinale Roscoe, known as ginger (Bentong variety), is an essential spice
ingredient used in food and condiments due to its refreshing aroma and intense flavour.
The bioactive constituents found in ginger influence the numerous pharmacological
effects, including antioxidant, analgesic, anticancer, antipyretic and anti-inflammatory.
This work proposed a greener approach than the conventional plant matrices extraction to
promote safe, non-toxic, and environment-friendly products. In this study, three different
extraction methods: a) water (WE), b) hydrothermal-assisted (HAE) and c) enzymaticassisted (EAE), have been applied to measure the potential of both ginger extracts from
different cultivation methods using fertigation technology and conventionally slopegrown. To ascertain the biological content of the extracts, the phenolic acid composition
was quantified using ultra-performance liquid chromatography (UPLC). The total
phenolic content (TPC) was determined using the Folin-Ciocalteu method, while the
antioxidant activities were analysed using ferric reducing antioxidant power (FRAP) and
2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay. The results obtained
showed that ferulic acid was significantly highest in EAE extracts of both ginger
(fertigation and slope-grown cultivation) at 1.165±0.118 and 0.610±0.062 mg/g.
Moreover, EAE of both ginger extracts also found to be significantly highest in TPC
(267.481±0.404 mg GAE/g and 247.837±1.675 mg GAE/g), and FRAP value
(741.867±2.139 mg AAE/g and 461.733±0.231 mg AAE/g), respectively. However, the
highest free radical scavenging activity of fertigated ginger extract through HAE was
134.735±0.021 mg AAE/g. Meanwhile, EAE of the sloped-grown ginger extract was
highest at 141.293±0.707 mg AAE/g. This study demonstrates that EAE can be an
effective approach in enhancing the TPC and antioxidant activity of ginger extracts.
Ginger may therefore be suggested as a more greener and natural antioxidant to lessen
oxidation in food products.
Analysis of the Effects and Incidence of Adverse Reactions of Hormone Replacement Therapy for Perimenopausal Syndrome
Authors: Cai Yu
Published: March 2024

Objective: To introduce hormone replacement therapy for patients with perimenopausal syndrome and observe its clinical application effect. Methods: Patients with perimenopausal syndrome were the subjects of this study, with a total of 110 participants clinically admitted from January 2022 to December 2023. Upon enrollment, patients were divided into groups based on differences in treatment modes. The observation group (n = 55) received routine health care combined with hormone replacement therapy, while the control group (n = 55) received only routine health care treatment. Evaluation criteria included psychological state, symptom scores, improvement in hormone levels, and the incidence of adverse reactions. The clinical effects of different treatment options were compared. Results: Post-treatment, scores of the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS) in the observation group were significantly lower than those in the control group (P < 0.05). Additionally, the female menopausal syndrome self-diagnosis assessment scale (Kupperman) score was 12.31 ± 1.25 points in the observation group compared to 15.22 ± 1.84 points in the control group (t = 9.7018, P < 0.05). Furthermore, levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were lower in the observation group than in the control group, while estradiol (E2) and progesterone levels were higher in the observation group than in the control group (P < 0.05). There was no statistically significant difference in the total incidence of adverse reactions between the observation and control groups (P > 0.05). Conclusion: The application of hormone replacement therapy in Chinese medicine can improve patients’ mental state, alleviate clinical symptoms, and restore hormone levels. This treatment modality is deemed safe with minimal adverse reactions, thus offering positive value.
Analysis of the Short-Term Curative Effect of Roxadustat in Treating Renal Anemia in Patients with Peritoneal Dialysis
Authors: Cao Yuechun , Gao Jianmin , Zhu Qiang , Miao Shuhang , Tao Run
Published: March 2024

Objective: To analyze the short-term curative effect of roxadustat in the treatment of renal anemia in patients with peritoneal dialysis. Methods: 70 patients with peritoneal dialysis renal anemia admitted to the dialysis department of our hospital from March 2021–March 2023 were selected as research objects, divided into a research group and a reference group according to random number drawing method, with each group consisting of 35 cases. The patients in the research group were treated with roxadustat, and those in the reference group were treated with recombinant human erythropoietin. The total efficacy, anemia index, iron metabolism index, and occurrence of adverse reactions were compared between the two groups. Results: The total efficacy of the treatment received in the research group was significantly higher than that in the reference group (P < 0.05). In terms of anemia indicators, there was no statistically significant difference between the hemoglobin (Hb), the red blood cell (RBC), and the hematocrit (HCT) of both groups (P > 0.05) before treatment. After treatment, the anemia indicators of the patients in the research group were significantly better than those in the reference group, (P < 0.05). In terms of iron metabolism, before treatment, there was no significant difference between the total iron-binding capacity (TIBC), the transferrin (TRF), the ferritin (FER), and iron (Fe) of both groups (P > 0.05). After treatment, the research group’s iron metabolism indicators were significantly better than those of the reference group (P < 0.05). The incidence of adverse reactions in the research group was significantly lower than that in the reference group (P < 0.05). Conclusion: The short-term curative effect of roxadustat in the treatment of peritoneal dialysis patients was demonstrated through this study, making it a viable treatment option.
The Value of RDW, PDW, and Immunoglobulin E in the Clinical Diagnosis of Pediatric Asthma
Authors: Wan Xuelong
Published: March 2024

Objective: To observe and explore the value of the combined application of red blood cell distribution width (RDW), platelet distribution width (PDW), and immunoglobulin E (IgE) in the process of clinical diagnosis of children with asthma. Methods: Fifty-five children with suspected asthma were admitted to the hospital from July 2021 to July 2023. They underwent a bronchodilator test upon admission and their RDW, PDW, and IgE were detected. The efficacy of diagnosis with a single indicator (RDW/PDW/IgE) and combined parameters (PDW + PDW + IgE) were compared with the results of the bronchodilator test. Results: 49 cases of pediatric asthma were diagnosed by the bronchodilator test. RDW and PDW of asthmatic children were lower than those of non-asthmatic children, while the IgE of asthmatic children was higher than that of non-asthmatic children, and there was a significant difference in the RDW, PDW, and IgE among children with different degrees of asthma severity (P < 0.05). The positive rate of the three combined diagnostic tests of RDW, PDW, and IgE was significantly higher than the positive rate of a single-parameter diagnosis (P < 0.05). Conclusion: The combination of RDW, PDW, and IgE plays a crucial role in the clinical diagnosis of asthmatic children. These tests further improve the efficiency of clinical diagnosis and help identify the severity of the disease.
Effect of CT-Guided Microwave Ablation Combined with TACE on Liver Function and Survival of Patients with Primary Liver Cancer
Authors: Chen Bo , Shi Donghong , Ai Min , Zhang Longjiang
Published: March 2024

Objective: To explore the effect of transarterial chemoembolization (TACE) + CT-guided microwave ablation (MWA) on treating patients with primary liver cancer. Methods: 78 primary liver cancer cases were enrolled and divided into groups according to their assigned surgical plans. The control group was treated with TACE alone, and the observation group was treated with TACE + CT-guided MWA. The efficacy of the treatment and the liver function indicators and follow-up results of the patients of the two groups were compared. Results: The efficacy of the treatment received by the observation group was higher than that of the control group. Besides, the patients in the observation group exhibited better improvement in liver function indicators after 3 months of treatment. Furthermore, the survival rates of 1 and 2 years after surgery of the observation group were all higher than those of the control group (P < 0.05). Conclusion: TACE combined with CT-guided MWA is more effective in treating primary liver cancer compared to TACE alone. Besides, it resulted in better improvement of liver function and long-term survival rate. Therefore, this treatment regime should be popularized.