bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of a Risk Register Spreadsheet Tool for Enterprise- and Program-Level Risk Management
Authors: O'Har John Patrick , Senesi Christopher W. , Molenaar Keith R.
Published: February 2017

Enterprise risk management is an area of growing interest for state departments of transportation in the United States. This research developed a risk register spreadsheet tool—applicable at the enterprise and program levels—that supports the user in identifying risk events, defining risk categories, and assessing the likelihood (probability) and consequence (effect) of an event occurring. A state-of-the-practice survey was conducted with regard to the use of risk register tools to support enterprise- and program-level risk management at U.S. state departments of transportation, international transportation agencies, and nontransportation organizations. On the basis of the survey results and to further inform development of the risk register tool, several organizations were selected for in-depth interviews to gather additional information on their risk management practices and use of risk register tools. The resultant risk register reflects information from the interviews and examples provided by the participants. The spreadsheet-based risk register is an editable template that does not use any macros or custom code. In addition to the editable template, two prepopulated examples—one for enterprise-level risk management and one for program-level risk management—were created. While the risk register tool can help facilitate good practice risk management, the findings of this research indicate that an organization's risk management governance along with staff commitment, availability, and capability to support risk management activities are equally, if not more, important to effective risk management as the risk register tool itself.
Genetic Testing for Autism Spectrum Disorder is Lacking Evidence of Cost-effectiveness
Authors: Rudolph-Rothfeld Wolfgang , Vonthein Reinhard , Ziegler Andreas
Published: February 2017

Background: Autism Spectrum Disorder (ASD) is a highly heritable neural development disorder characterized by social impairment. The earlier the diagnosis is made, the higher are the chances of obtaining relief of symptoms. A very early diagnosis uses molecular genetic tests, which are also offered commercially.

Objective: Systematic review of the economic impact of genetic tests in ASD.

Methods: We performed a systematic search of databases Pubmed, Medline, Cochrane, Econlit and the NHS Center for Reviews and Dissemination for articles in English and German from January 1, 2000 to December 31, 2015. Original articles published in peer- reviewed journals were screened in a two- step process. First, we focused our search on economic evaluations of genetic tests for ASD. Second, we searched for any economic evaluation (EE) of genetic tests.

Results: We identified 185 EE of genetic tests for various diseases. However, not a single EE of genetic tests has been found for ASD. The outcomes used in the EE of the genetic tests were heterogeneous, and results were generally not comparable.

Conclusion: There is no evidence for cost-effectiveness of any genetic diagnostic test for ASD, although such genetic tests are available commercially. Cost-effectiveness analyses for genetic diagnostic tests for ASD are urgently required. There is a clear lack in research for EE of genetic tests.
Increasing the Efficiency on Producing Radiology Reports for Breast Cancer Diagnosis by Means of Structured Reports
Authors: Medina Rosana , Blanquer Ignacio , Martí-Bonmatí Luis , Segrelles J. Damian
Published: February 2017

Background: Radiology reports are commonly written on free-text using voice recognition devices. Structured reports (SR) have a high potential but they are usually considered more difficult to fill-in so their adoption in clinical practice leads to a lower efficiency. However, some studies have demonstrated that in some cases, producing SRs may require shorter time than plain-text ones. This work focuses on the definition and demonstration of a methodology to evaluate the productivity of software tools for producing radiology reports. A set of SRs for breast cancer diagnosis based on BI-RADS have been developed using this method. An analysis of their efficiency with respect to free-text reports has been performed.

Material and Methods: The methodology proposed compares the Elapsed Time (ET) on a set of radiological reports. Free-text reports are produced with the speech recognition devices used in the clinical practice. Structured reports are generated using a web application generated with TRENCADIS framework. A team of six radiologists with three different levels of experience in the breast cancer diagnosis was recruited. These radiologists performed the evaluation, each one introducing 50 reports for mammography, 50 for ultrasound scan and 50 for MRI using both approaches. Also, the Relative Efficiency (REF) was computed for each report, dividing the ET of both methods. We applied the T-Student (T-S) test to compare the ETs and the ANOVA test to compare the REFs. Both tests were computed using the SPSS software.

Results: The study produced three DICOM- SR templates for Breast Cancer Diagnosis on mammography, ultrasound and MRI, using RADLEX terms based on BIRADs 5th edition. The T-S test on radiologists with high or intermediate profile, showed that the difference between the ET was only statistically significant for mammography and ultrasound. The ANOVA test performed grouping the REF by modalities, indicated that there were no significant differences between mammograms and ultrasound scans, but both have significant statistical differences with MRI. The ANOVA test of the REF for each modality, indicated that there were only significant differences in Mammography (ANOVA p = 0.024) and Ultrasound (ANOVA p = 0.008). The ANOVA test for each radiologist profile, indicated that there were significant differences on the high profile (ANOVA p = 0.028) and medium (ANOVA p=0.045).

Conclusions: In this work, we have defined and demonstrated a methodology to evaluate the productivity of software tools for producing radiology reports in Breast Cancer. We have evaluated that adopting Structured Reporting in mammography and ultrasound studies in breast cancer diagnosis improves the performance in producing reports.
Evaluation Results of an Ontology-based Design Model of Virtual Environments for Upper Limb Motor Rehabilitation of Stroke Patients
Authors: Morán Alberto L. , García-Canseco Eloísa , Gómez-Montalvo Jorge R. , Ramírez-Fernández Cristina
Published: February 2017

Objectives: 1) To enhance the content of an ontology for designing virtual environments (VEs) for upper limb motor rehabilitation of stroke patients according to the suggestions and comments of rehabilitation specialists and software developers, 2) to characterize the perceived importance level of the ontology, 3) to determine the perceived usefulness of the ontology, and 4) to identify the safety characteristics of the ontology for VEs design according to the rehabilitation specialists.

Methods: Using two semi-structured Web questionnaires, we asked six rehabilitation specialists and six software developers to provide us with their perception regarding the level of importance and the usability of the ontology. From their responses we have identified themes related to perceived and required safety characteristics of the ontology.

Results: Significant differences in the importance level were obtained for the Stroke Disability, VE Configuration, Outcome Measures, and Safety Calibration classes, which were perceived as highly important by rehabilitation specialists. Regarding usability, the ontology was perceived by both groups with high usefulness, ease of use, learnability and intention of use. Concerning the thematic analysis of recommendations, eight topics for safety characteristics of the ontology were identified: adjustment of therapy strategies; selection and delimitation of movements; selection and proper calibration of the interaction device; proper selection of measuring instruments; gradual modification of the difficulty of the exercise; adaptability and variability of therapy exercises; feedback according to the capabilities of the patient; and real-time support for exercise training.

Conclusions: The rehabilitation specialists and software developers confirmed the importance of the information contained in the ontology regarding motor rehabilitation of the upper limb. Their recommendations highlight the safety features and the advantages of the ontology as a guide for the effective design of VEs.
Continuous N-alkylation reactions of amino alcohols using γ-Al2O3 and supercritical CO2: unexpected formation of cyclic ureas and urethanes by reaction with CO2
Authors: Streng Emilia S , Lee Darren S , George Michael W , Poliakoff Martyn
Published: February 2017

The use of γ-Al2O3 as a heterogeneous catalyst in scCO2 has been successfully applied to the amination of alcohols for the synthesis of N-alkylated heterocycles. The optimal reaction conditions (temperature and substrate flow rate) were determined using an automated self-optimising reactor, resulting in moderate to high yields of the target products. Carrying out the reaction in scCO2 was shown to be beneficial, as higher yields were obtained in the presence of CO2 than in its absence. A surprising discovery is that, in addition to cyclic amines, cyclic ureas and urethanes could be synthesised by incorporation of CO2 from the supercritical solvent into the product.
Profile Of Burn Victims Attended By An Emergency Unit
Authors: Souza Lima Lidiane , Oliveira de Sousa Correia Viviane , Garção Nascimento Tycianne Karoline , Pinto Chaves Bárbara Jeane , Santos Silva José Rodrigo , Barreto Alves José Antônio , Vieira Dantas Daniele , De Oliveira Ribeiro Maria do Carmo
Published: February 2017

Objectives: to identify the sociodemographic and health profile of burn victims, knowing the characteristics of the events and detecting the major analgesics prescribed in the emergency department.

Methods: descriptive, exploratory and quantitative study with 16 burn victims treated at a Burn Treatment Unit from October 2015 to May 2016.

Results: the average age of participants was 31.8 years (± 14.1). Mostly, the subjects were male (62.5%), single (43.8%), brown (68.8%), economically active (75.0%) and coming from Aracaju and its surroundings (62.5%). Injuries from burns were mostly of second degree (93.8%) and reached the lower limbs (68.8%). The average burned body surface was 15.8% (± 11.5). The circumstances surrounding burns occurred mainly at home (50.0%), on Sundays (25.0%) and in the shifts morning (37.5%) and night (37.5%). The main etiological agent was alcohol (31.3%). All patients received analgesia in the emergency department, but the minority had pain documented (18.8%). The physician was the only professional who reported pain in their records, but did incompletely (18.8%).

Conclusion: due to the negative effects of burns, it is crucial to adopt educational and preventive measures to change the current scenario of epidemiology of such trauma.

Keywords: Burns; Epidemiology; Analgesia; Emergency.
Is Music Effective For Pain Relief In Burn Victims?
Authors: Souza Lima Lidiane , Oliveira de Sousa Correia Viviane , Garção Nascimento Tycianne Karoline , Pinto Chaves Bárbara Jeane , Santos Silva José Rodrigo , Barreto Alves José Antonio , Vieira Dantas Daniele , De Oliveira Ribeiro Maria do Carmo
Published: February 2017

Objective: to describe the effect of music on pain of burn victims during the dressing change.

Methods: applied, descriptive, exploratory and quantitative research held in a Burn Treatment Unit from October 2015 to April 2016. The study included 16 burn victims who were divided in three groups: A: patients heard music before dressing; B: patients hear music during dressing; C: patients did not hear music.

Results: the average age was 31.8 years (± 14.1) and most of the subjects were male. Lower limbs and trunk were the most affected parts of the body, especially with second-degree burns and which affected an average of 15.8% (± 11.5) of the body surface. There was a predominance of gospel music (50.0%). The music reduced the average heart rate and oxygen saturation, but did not change ventilatory rate. There was a decrease in the average of pain intensity in groups GB (p = 0.0505 and GC (p = 0.0055). During the dressing, the burning was unanimous characteristic for all subjects, in the same manner as verbal reports was the form of manifestation.

Conclusion: music proved to be a simple and effective resource in controlling pain in burn victims.

Keywords: Burns; Music; Pain.
Trachoma as cause of blindness: literature review
Authors: Araújo Silva Maria Beatriz , Andrade Maria Sandra , De Oliveira Yohana Véras , Santiago Marques Maria Gabriela , Mourão Pinho Clarissa , Araújo de Miranda Lopes Katiuscia
Published: February 2017

This is a literature review that used as database articles in websites like Bireme, SciELO, LILACS, Journals and Webartigos. Development: Trachoma is an ocular inflammatory disease, whose etiological agent is Chlamydia trachomatis, which affects the conjunctiva and cornea causing a chronic relapsing keratoconjunctivitis, in the course of time may lead to the formation of entropion, trichiasis and possible blindness. Its transmission occurs in the home environment, directly or indirectly. The occurrence of trachoma is mostly where hygiene and lifestyle habits are precarious. According to the World Health Organization, there are six million people currently infected. Conclusion: The study shows the importance of knowledge about trachoma, so that Brazil is able to achieve the global goal of eliminating the disease by 2020.
Trojan Asteroids in the Kepler Campaign 6 Field
Authors: Ryan Erin Lee , Sharkey Benjamin N. L. , Woodward Charles E.
Published: February 2017

We report on a Kepler spacecraft survey during the K2 mission to characterize the rotational properties of 56 Trojan asteroids in the L4 cloud. More than one rotational period was observed for 51 of these targets, allowing for well constrained lightcurve rotation periods and amplitudes, five of which are found to be in conflict with previously published values. We find ∼10% of objects have rotational periods longer than 100 hr, an excess of slow rotators 10 times larger than suggested from the literature. Investigation of the rotational frequencies of our Kepler sample when combined with high-quality lightcurves in the literature reveals the distribution of rotational frequencies is non-Maxwellian even when consideration is given to size-dependent variations in rotational rate. From investigation of lightcurve shapes and amplitudes, we estimate the binary fraction within the Trojan population to be ∼6%–36% depending on the methodology utilized to identify binary candidates.
A Luminous and Isolated Gamma-Ray Flare from the Blazar B2 1215+30
Authors: Abeysekara A. U. , Archambault S. , Archer A. , Benbow W. , Bird R. , Buchovecky M. , Buckley J. H. , Bugaev V. , Byrum K. , Cerruti M. , Chen X. , Ciupik L. , Cui W. , Dickinson H. J. , Eisch J. D. , Errando M. , Falcone A. , Feng Q. , Finley J. P. , Fleischhack H. , Fortson L. , Furniss A. , Gillanders G. H. , Griffin S. , Grube J. , Hütten M. , Håkansson N. , Hanna D. , Holder J. , Humensky T. B. , Johnson C. A. , Kaaret P. , Kar P. , Kertzman M. , Kieda D. , Krause M. , Krennrich F. , Kumar S. , Lang M. J. , Maier G. , McArthur S. , McCann A. , Meagher K. , Moriarty P. , Mukherjee R. , Nguyen T. , Nieto D. , Ong R. A. , Otte A. N. , Park N. , Pelassa V. , Pohl M. , Popkow A. , Pueschel E. , Quinn J. , Ragan K. , Reynolds P. T. , Richards G. T. , Roache E. , Rulten C. , Santander M. , Sembroski G. H. , Shahinyan K. , Staszak D. , Telezhinsky I. , Tucci J. V. , Tyler J. , Wakely S. P. , Weiner O. M. , Weinstein A. , Wilhelm A. , Williams D. A. ,   (VERITAS Collaboration), Fegan S. , Giebels B. , Horan D. ,   (Fermi-LAT Collaboration), Berdyugin A. , Kuan J. , Lindfors E. , Nilsson K. , Oksanen A. , Prokoph H. , Reinthal R. , Takalo L. , Zefi F.
Published: February 2017

B2 1215+30 is a BL-Lac-type blazar that was first detected at TeV energies by the MAGIC atmospheric Cherenkov telescopes and subsequently confirmed by the Very Energetic Radiation Imaging Telescope Array System (VERITAS) observatory with data collected between 2009 and 2012. In 2014 February 08, VERITAS detected a large-amplitude flare from B2 1215+30 during routine monitoring observations of the blazar 1ES 1218+304, located in the same field of view. The TeV flux reached 2.4 times the Crab Nebula flux with a variability timescale of

<
3.6

hr

. Multiwavelength observations with Fermi-LAT, Swift, and the Tuorla Observatory revealed a correlated high GeV flux state and no significant optical counterpart to the flare, with a spectral energy distribution where the gamma-ray luminosity exceeds the synchrotron luminosity. When interpreted in the framework of a one-zone leptonic model, the observed emission implies a high degree of beaming, with Doppler factor

δ
>
10

, and an electron population with spectral index

p
<
2.3

.
Planetesimal Clearing and Size-dependent Asteroid Retention by Secular Resonance Sweeping during the Depletion of the Solar Nebula
Authors: Zheng(郑晓晨) Xiaochen , Lin(林潮) Douglas N. C. , Kouwenhoven(柯文采) M. B. N.
Published: February 2017

The distribution of heavy elements is anomalously low in the asteroid main belt region compared with elsewhere in the solar system. Observational surveys also indicate a deficit in the number of small (≲50 km size) asteroids, which is two orders of magnitude lower than what is expected from the single power-law distribution that results from a collisional coagulation and fragmentation equilibrium. Here, we consider the possibility that a major fraction of the original asteroid population may have been cleared out by Jupiter’s secular resonance, as it swept through the main asteroid belt during the depletion of the solar nebula. This effect leads to the excitation of the asteroids’ orbital eccentricities. Concurrently, hydrodynamic drag and planet–disk tidal interaction effectively damp the eccentricities of sub-100 km-size and of super-lunar-size planetesimals, respectively. These combined effects lead to the asteroids’ orbital decay and clearing from the present-day main belt region (∼2.1–3.3 au). Eccentricity damping for the intermediate-size (50 to several hundreds of kilometers) planetesimals is less efficient than for small or large planetesimals. These objects therefore preferentially remain as main belt asteroids near their birthplaces, with modest asymptotic eccentricities. The smaller asteroids are the fragments of subsequent disruptive collisions at later times as suggested by the present-day asteroid families. This scenario provides a natural explanation for both the observed low surface density and the size distribution of asteroids in the main belt, without the need to invoke special planetesimal formation mechanisms. It also offers an explanation for the confined spatial extent of the terrestrial planet building blocks without the requirement of extensive migration of Jupiter, which is required in the grand-tack scenario.
On Integral Upper Limits Assuming Power-law Spectra and the Sensitivity in High-energy Astronomy
Authors: Ahnen Max L.
Published: February 2017

The high-energy non-thermal universe is dominated by power-law-like spectra. Therefore, results in high-energy astronomy are often reported as parameters of power-law fits, or, in the case of a non-detection, as an upper limit assuming the underlying unseen spectrum behaves as a power law. In this paper, I demonstrate a simple and powerful one-to-one relation of the integral upper limit in the two-dimensional power-law parameter space into the spectrum parameter space and use this method to unravel the so-far convoluted question of the sensitivity of astroparticle telescopes.
The Nearest Ultra Diffuse Galaxy: UGC 2162
Authors: Trujillo Ignacio , Roman Javier , Filho Mercedes , Almeida Jorge Sánchez
Published: February 2017

We describe the structural, stellar population and gas properties of the nearest ultra diffuse galaxy discovered so far: UGC 2162 (z = 0.00392;

kpc;

 = 24.4 ± 0.1 mag arcsec−2;

 = 0.33 ± 0.02). This galaxy, located at a distance of 12.3(±1.7) Mpc, is a member of the M77 group. UGC 2162 has a stellar mass of

× 107

and is embedded within a cloud of HI gas ∼10 times more massive: ∼1.9(±0.6) × 108

. Using the width of its HI line as a dynamical proxy, the enclosed mass within the inner R ∼ 5 kpc is ∼4.6(±0.8) × 109

(i.e., M/L ∼ 200). The estimated virial mass from the cumulative mass curve is ∼8(±2)×1010
M
⊙. Ultra-deep imaging from the IAC Stripe82 Legacy Project show that the galaxy is irregular and has many star-forming knots, with a gas-phase metallicity around one-third of the solar value. Its estimated star-formation rate is ∼0.01

yr−1. This SFR would double the stellar mass of the object in ∼2 Gyr. If the object were to stop forming stars at this moment, after a passive evolution, its surface brightness would become extremely faint:

27 mag arcsec−2 and its size would remain large

1.8 kpc. Such faintness would make it almost undetectable to most present-day surveys. This suggests that there could be an important population of

107

“dark galaxies” in rich environments (depleted of HI gas) waiting to be discovered by current and future ultra-deep surveys.
Gravitational Focusing and the Star Cluster Initial Mass Function
Authors: Kuznetsova Aleksandra , Hartmann Lee , Burkert Andreas
Published: February 2017

We discuss the possibility that gravitational focusing is responsible for the power-law mass function of star clusters

. This power law can be produced asymptotically when the mass accretion rate of an object depends upon the mass of the accreting body, as

. Although Bondi–Hoyle–Lyttleton accretion formally produces this dependence on mass in a uniform medium, realistic environments are much more complicated. However, numerical simulations in SPH that allow for sink formation yield such an asymptotic power-law mass function. We perform pure N-body simulations to isolate the effects of gravity from those of gas physics and to show that clusters naturally result with the power-law mass distribution. We also consider the physical conditions necessary to produce clusters on appropriate timescales. Our results help support the idea that gravitationally dominated accretion is the most likely mechanism for producing the cluster mass function.
Soigner les migrants dans les PASS
Authors: Georges-Tarragano Claire , Grassineau Dominique , Astre Harold , Gaillard Julien
Published: February 2017

L’afflux massif de réfugiés et de migrants appelle une réponse urgente à leurs besoins sanitaires. Celle-ci est assurée par les Permanences d’accès aux soins de santé médico-sociales (PASS), pour des patients vulnérables. Ces lieux d’accueil, d’information, de prévention, d’orientation et de soins sociaux et médicaux sont un modèle de pratique ouvrant des perspectives à l’ensemble du système de santé français.
Sobre la gestión del patrimonio natural y el paisaje en España en la era de los Espacios Naturales Protegidos: el caso de los invertebrados
Authors: Gómez Jose F. , Bourgès Flora
Published: February 2017

En las últimas décadas, en lo que a gestión del patrimonio natural se refiere, el papel de los Espacios Naturales Protegidos ha cobrado una gran relevancia en el campo de la biología de la conservación al constituirse como áreas gestionadas para la conservación de especies de flora y fauna. Estos espacios se encuentran en muchos casos rodeados de zonas de aprovechamiento de recursos agroganaderos, con las cuales forman unidades de paisaje de gran importancia para el mantenimiento de la biodiversidad. Analizar el papel de estas unidades de paisaje como áreas interconectadas en mosaico y de interés para especies y comunidades de fauna de alto valor ecológico representa un objetivo necesario y de interés general para la gestión sostenible del paisaje y el patrimonio natural. Sobre muchas poblaciones de invertebrados e insectos dentro de estas unidades de paisaje, aun estando en un segundo plano respecto a otros elementos que han despertado mayor interés social o científico, confluyen tales circunstancias, por su papel determinante en el mantenimiento de la diversidad de ecosistemas y flujo de sus poblaciones dentro y fuera de los Espacios Naturales Protegidos, y el hecho de que a veces constituyen unidades de biodiversidad sobre las que se ha basado la gestión de estos espacios. En el presente texto, a través del caso de los Lepidoptera (Hexapoda) se pretende poner de manifiesto la importancia que tiene para la conservación de los invertebrados e insectos una gestión integral del patrimonio natural y el paisaje de nuestro país, todo ello dentro del contexto de la biología de la conservación.
History of Newcastle disease in South Africa
Authors: Abolnik Celia
Published: February 2017

Poultry production in South Africa, a so-called developing country, may be seen as a gradient between two extremes with highly integrated commercial enterprises with world-class facilities on one hand and unimproved rural chickens kept by households and subsistence farmers on the other. Although vaccination against Newcastle disease is widely applied to control this devastating infection, epizootics continue to occur. Since the first official diagnosis in 1945, through the sporadic outbreaks of the 1950s and early 1960s, to serious epizootics caused by genotype VIII (late 1960s–2000), genotype VIIb (1993–1999), genotype VIId (2003–2012) and most recently genotype VIIh (2013 to present), South Africa’s encounters with exotic Newcastle disease follow global trends. Importation – probably illegal – of infected poultry, poultry products or exotic birds and illegal swill dumping are likely routes of entry. Once the commercial sector is affected, the disease spreads rapidly within the region via transportation routes. Each outbreak genotype persisted for about a decade and displaced its predecessor.
A classification of torsors over Laurent polynomial rings
Authors: Chernousov Vladimir , Gille Philippe , Pianzola Arturo
Published: February 2017

Let

R_n

be the ring of Laurent polynomials in

n

variables over a field

k

of characteristic zero and let

K_n

be its fraction field. Given a linear algebraic

k

-group

G

, we show that a

K_n

-torsor under

G

which is unramified with respect to

X

= Spec

(R_n)

extends to a unique toral

R_n

-torsor under

G

. This result, in turn, allows us to classify all

G

-torsors over

R_n

.
On a modular Fermat equation
Authors: Pila Jonathan
Published: February 2017

We study some diophantine problems suggested by the analogy between multiplicative groups and powers of the modular curve in problems of “unlikely intersections”. We prove a special case of the Zilber–Pink conjecture for curves.
The Hadamard Product and the Karcher Mean of Positive Invertible Operators
Authors: Seo Yuki
Published: February 2017

In this paper, we show several operator inequalities involving the Hadamard product and the Karcher mean of

n (≥3)

positive invertible operators on a separable Hilbert space, which are regarded as an

n

-variable operator version of results due to Ando and Aujla–Vasudeva. As applications, we show estimates from above for an

n

-variable version of the Fiedler-type theorem due to Fujii. Moreover, we show an

n

-variable version of the majorization relation due to Ando for the Hadamard product via the Karcher mean of

n (≥ 3)

positive-definite matrices.
Two-Weight Norm, Poincaré, Sobolev and Stein–Weiss Inequalities on Morrey Spaces
Authors: Ho Kwok-Pun
Published: February 2017

We establish two-weight norm inequalities for singular integral operators and fractional integral operators on Morrey spaces. As a consequence of these inequalities, we obtain two-weight Poincaré and Sobolev inequalities on Morrey spaces. Moreover, we also establish the Stein–Weiss inequality, the Hardy inequality and the Rellich inequality on Morrey spaces.
Emboles lymphatiques des carcinomes mammaires invasifs félins : amélioration de leur détection par immunohistochimie et valeur pronostique
Authors: Besnard Fanny
Published: February 2017

Notre étude rétrospective avec suivi clinique de 350 chattes a pour objectifs de déterminer la fréquence de l’embolisation lymphatique et sa corrélation avec les autres caractéristiques du carcinome mammaire invasif félin, de valider un marqueur immunohistochimique d’aide à la mise en évidence des emboles lymphatiques et de déterminer s’il améliore la prédiction pronostique. Nos résultats indiquent que l’invasion lymphovasculaire concerne 41% des carcinomes mammaires, notamment ceux de grande taille et/ ou de haut grade et/ ou négatifs pour le récepteur à la progestérone. L’embolisation lymphatique est un facteur pronostique fort lié au risque de généralisation métastatique et de décès lié au cancer. Dans près de 8% des cas, les coupes histologiques colorées par l’hémalun-éosine-safran (HES) ne permettent pas de statuer avec certitude sur sa présence. Le marqueur LMO2 (LIM-only domain protein-2), spécifique de l’endothélium lymphatique, permet de reclasser les cas douteux et participe à prédire le risque de décès des chattes à court terme après l’exérèse chirurgicale du carcinome.
Application thérapeutique potentielle de l’hypothermie par ventilation liquide
Authors: Tissier Renaud
Published: February 2017

L’hypothermie thérapeutique est la réduction de la température des patients afin d’augmenter leur résistance à une agression ischémique, notamment après un arrêt cardiaque. Le bénéfice dépend de la rapidité d’induction de l’hypothermie. Afin de déclencher un refroidissement rapide, il est possible d’utiliser expérimentalement le poumon comme échangeur thermique en lui administrant des liquides perfluorocarbones capables d’assurer les échanges gazeux tout en entrainant des échanges thermiques. Des prototypes expérimentaux permettent de réduire la température de l’ensemble de l’organisme jusqu’à 32-34° C en seulement 15 à 20 min chez des lapins, des porcs ou des brebis. Le refroidissement présente l’avantage de ne pas dépendre de la masse corporelle. Il engendre de puissants effets neuro-et cardio-protecteurs dans les modèles animaux d’arrêt cardiaque ou d’ischémie régionale. Le développement de tels dispositifs en clinique pourrait permettre de tester cette approche thérapeutique dans les situations critiques de réanimation en médecine humaine et vétérinaire.
Exposition aux gaz d’échappement diesel durant la gestation : quelles conséquences sur le développement foeto-placentaire ? Apport des modèles animaux
Authors: Valentino Sarah , Couturier-Tarrade Anne , Chavatte-Palmer Pascale
Published: February 2017

La pollution atmosphérique est un problème majeur pour la santé humaine, causant 3,7 millions de décès prématurés en 2012 dans le monde. Les personnes âgées, les enfants ou les asthmatiques sont les cibles des messages de prévention lors de pics de pollution alors que les femmes enceintes sont le plus souvent négligées. Pourtant, les études épidémiologiques et les travaux sur les modèles animaux indiquent que la pollution atmosphérique et ses composants peuvent perturber la fonction placentaire, réduire la croissance foetale et induire un stress oxydant et une inflammation. A long terme, ces effets peuvent participer à l’augmentation des risques de maladies métaboliques chez l’adulte. Il est donc important d’inclure les femmes enceintes dans les messages de prévention lors de pics de pollution atmosphérique et de continuer la recherche sur les effets à long terme grâce au recours aux modèles animaux.
Ecoantibio : premier plan de réduction des risques d’antibiorésistance en médecine vétérinaire (2012-2016)
Authors: Debaere Olivier
Published: February 2017

Ecoantibio : first plan for the reduction of the risks of antibiotic resistance in veterinary medicine (2012-2016).

The Ecoantibio plan is the French plan for the reduction of the risks of antibiotic resistance in veterinary medicine. It aims to reduce by 25% in five years (2012 to 2016 inclusive) the exposure of animals to antibiotics and to change the practices of prescribing and of use of antibiotics. With a drop of 20% in four years (2012-2015 inclusive), the quantified objective of the plan is about to be reached. These first good results, which can be qualified according to the families of antibiotics and animal sectors, are primarly related to the commitment and mobilization of veterinarians with farmers. However, it must be followed by a second plan to record the first good results in duration.
Chirurgie de laryngoplastie chez le cheval debout
Authors: Rossignol Fabrice
Published: February 2017

Une ventriculo-cordectomie uni ou bilatérale par laser, suivie d’une laryngoplastie, a été effectuée sous contrôle endoscopique chez des chevaux tranquillisés avec désensibilisation du site chirurgical par une anesthésie locale. La laryngoplastie a été bien tolérée sans aucune hyperabduction du cartilage aryténoïde paralysé. Les complications telles que toux, dysphagie et les complications de plaie sont survenues dans un nombre minimal de chevaux. L’analyse des résultats à long terme a montré une résolution des signes cliniques respiratoires chez environ 95 % des chevaux. La laryngoplastie effectuée chez le cheval debout permet d’éviter les risques associés à l’anesthésie générale et au réveil et donne des résultats au moins équivalents à à ceux de la laryngoplastie réalisée sous anesthésie générale. L’avantage principal de cette technique est de permettre un ajustement peropératoire précis du degré d’abduction du cartilage aryténoïde.
Alimentation des vaches laitières et composition en acides gras du lait
Authors: Enjalbert Francis , Meynadier Annabelle
Published: February 2017

Dairy cow’s diet and milk fatty acids profile.

Milk fatty acids profile is important for consumers, since milk and milk products provide a large part of fat in human diets and since dietary fatty acids profile influences human health. Milk fatty acids originate in part from the diet, and ruminal digestion strongly affects fatty acids profile. These physiological specificities must be taken into account to modulate milk fatty acids profile by modifying dairy cow’s diet. The main diet characteristics that can affect milk fatty acids profile are the choice of forage (pasture or stored forage) and fat supplementation, usually as oilseeds. This article underlines dietary choices that allow the control of unsaturated, n-3 or trans fatty acids.
Coinfection with Hymenolepis nana, Hymenolepis diminuta, Giardia intestinalis, and Human Immunodeficiency Virus: A Case Report with Complex Immunologic Interactions
Authors: Pérez-Chacón Gladymar , Pocaterra Leonor A. , Rojas Elsy , Hernán Aurora , Jiménez Juan Carlos , Núñez Luz
Published: February 2017

We describe the case of a 43-year-old human immunodeficiency virus–infected man receiving combined antiretroviral therapy and coinfected with Hymenolepis nana, Hymenolepis diminuta, and Giardia intestinalis, presenting as chronic diarrhea and critical weight loss. Immunological aspects of these interactions are reviewed.
Hose Assemblies, Rubber, Hydraulic, Steel Wire Reinforced - Part 2: Ordering Information
Authors:   Hydraulic Hose and Hose Fittings Committee
Published: February 2017

This SAE Standard covers ordering information for steel wire reinforced rubber hose assemblies using connectors specified in SAE Standard J516 or all parts of ISO 12151 for use in hydraulic systems using petroleum based hydraulic fluids with maximum working pressures of 1.7 to 42 MPa. See SAE J1754-2, Table 8 for hose operating temperature ranges and identification codes.

NOTE: Working pressure is defined as maximum system pressure.
Hose Assemblies, Hydraulic, J517 100R Series Hose - Part 3: Procurement and Ordering Information
Authors:   Hydraulic Hose and Hose Fittings Committee
Published: February 2017

This SAE Standard covers procurement and ordering information for hose assemblies using SAE Standard J517 100R Series hoses and connectors specified in SAE Standard J516 or all parts of ISO 12151 for use in hydraulic systems using petroleum based hydraulic fluids.

NOTE: Working pressure is defined as maximum system pressure.
OBD Communications Compliance Test Cases for Heavy Duty Components and Vehicles
Authors:   Truck Bus Control and Communications Network Committee
Published: February 2017

The purpose of this Recommended Practice is to verify that vehicles and/or components are capable of communicating a
required set of information, in accordance with the diagnostic test messages specified in SAE J1939-73, to fulfill the offboard
diagnostic tool interface requirements contained in the government regulations cited below.

This document describes the tests, test methods, and results for verifying diagnostics communication from an off board
diagnostic tool (i.e., scan tool) to a vehicle and/or component. SAE members have generated this document to serve as a
guide for testing vehicles for compliance with ARB and other requirements for emissions-related on-board diagnostic
(OBD) functions for heavy duty engines used in medium and heavy duty vehicles.
Optional Pass-Thru Features
Authors:   Vehicle E E System Diagnostic Standards Committee
Published: February 2017

SAE J2534-1 defines a standard vehicle network interface that can be used to reprogram emission-related control modules. However, there is a need to support vehicles prior to the 2004 model year as well as non-emission related control modules.

The SAE J2534-2 document meets these needs by detailing extensions to an SAE J2534-1 specification. It is not required for an interface to be fully compliant with SAE J2534-1 specification to implement some of the features specified in this document. Together, these extensions provide the framework for a common interface to protect the software investment of the Vehicle OEMs and Scan Tool manufacturers.

Only the optional features will be described by this document and are based on the December 2004 publication of SAE J2534-1.
Off-Road Tire Fire Handling Guidelines
Authors:   MTC8, Tire and Rim
Published: February 2017

This SAE Informational report applies to tires used on off-road, rubber-tired work machines as identified in SAE J1116. This SAE document provides general guidelines for proper handling of potential and actual off-road tire fires and possible related explosions.
Use Cases for Communication Between Plug-in Vehicles and the Utility Grid
Authors:   Hybrid - EV Committee
Published: February 2017

This SAE Information Report establishes use cases for communication between plug-in electric vehicles and the electric power grid, for energy transfer and other applications.
Laboratory Measurement of the Acoustical Performance of Body Cavity Filler Materials
Authors:   Acoustical Materials Committee
Published: February 2017

This SAE Recommended Practice describes a laboratory test procedure for measuring the acoustical performance of a system consisting of a body cavity filler material formed into a rectangular cross-section channel. Materials for this test may include both heat reactive and chemically reactive products, with or without a shelf to simulate a baffle in an application, or a combination of body cavity filler and aluminum foil to enhance the performance. These materials are commonly installed in transportation systems such as ground vehicles, and thus reduce the noise propagation through the rails, rockers, and pillar/posts.

This document is intended to rank order the acoustical performance of materials for application on channels using general automotive steel, such that the effects of sealing of pinch welds in addition to the material could be easily evaluated. However, the channel is not an actual part (i.e., real life section) of the vehicle, and therefore results obtained from this study will have to be carefully interpreted considering limitations of section size/shape and full sealing (or not) of the section.

The acoustical performance is expressed in terms of insertion loss (IL) which is described in Section 3 Test Method. The test procedure described here is based on the method described in SAE J1400. However, this document differs from the SAE J1400 method in that the J1400 measures sound transmission loss, and this document measures IL of body cavity materials in a cavity.

This document covers the useful frequency range of interest in 1/3 octave band center frequencies. The lower limit of the actual frequency range is limited by the size of the channel and/or the volume of the reverberation room. Two rectangular cross-section channels are cited in this standard. These are 75 mm × 75 mm and 150 mm × 150 mm in cross-section and provide valid data at and above 800 Hz and 400 Hz 1/3 octave band frequencies, respectively, provided the reverberation room can generate diffuse sound field at those frequencies.
Power Cylinder Friction: Mechanisms
Authors:   Piston and Ring Standards Committee
Published: February 2017

This document covers the mechanisms from the power cylinder which contribute to the mechanical friction of an internal combustion engine. It will not discuss in detail the influence of other engine components or engine driven accessories on friction.
Engineering Design Serviceability Guidelines--Construction and Industrial Machinery--Serviceability Definitions--Off-Road Work Machines
Authors:   Machine Technical Steering Committee
Published: February 2017

This SAE Information Report establishes a hierarchy of Product Effectiveness, defines Serviceability, Maintainability, Repairability, and Diagnostics, and relates them to Product Effectiveness. Effectiveness of this procedure depends on its use during early stages of design.

This document applies to machines defined in J1057 and categorized in J1116.
Engineering Design Serviceability Guidelines--Construction and Industrial Machinery--Maintainability Index--Off-Road Work Machines
Authors:   Machine Technical Steering Committee
Published: February 2017

This SAE Information Report establishes a point system that encourages ease of maintenance actions on off-road work machines. The point system minimizes subjectivity in evaluating maintainability as defined in SAE J817/1.
SPECIFICATION FOR TESTING AUTOMOTIVE LAMP ASSEMBLIES
Authors:   USCAR
Published: February 2017

The procedures contained in this specification cover the laboratory testing of Exterior Lamps for use in automotive road illumination. The following tests are intended to be run under the following conditions.

This document shall be applied to systems that meet the requirements for design, performance and validation established by government standards.

If other manufacture’s components are intended to be approved for use in the lamp assembly, then those possible combinations of components shall be considered a new lamp assembly and shall also be tested.
Erazem iz Rotterdama: Reuchlinovo vnebovzetje (O neprimerljivem junaku Johannesu Reuchlinu, ki je bil sprejet med nebeščane)
Authors: Potočnik Tomaž
Published: February 2017

Leta 1510 so Johannesa Reuchlina, profesorja prava v Pforzheimu, ki je bil izkušen v cesarskih političnih zadevah in je slovel kot izjemen humanist in hebraist, prosili, naj poda mnenje o judovskih knjigah. Dve leti pred tem je Johannes Pfefferkorn, judovski spreobrnjenec v krščanstvo, svoje bivše soverce namreč obtožil posedovanja knjig, ki blatijo krščanstvo, in prepričal cesarja, naj ukaže zaplembo in pregled vseh knjig v lasti judov, da se odkrijejo morebitne krivoverske in protikrščanske prvine. Reuchlin je v svojem slavnem odgovoru branil zakonske pravice judov v cesarstvu in trdil, da judovske literature ni mogoče kar v celoti obravnavati kot protikrščanske. Po objavi tega odgovora je bil leta 1511 obtožen herezije, začela pa se je vsesplošna razprava o judovski literaturi, krščanski hebraistiki ter odnosu med humanističnimi filološkimi prizadevanji in krščansko teologijo. Reuchlin je nekaj let zelo uspešno zavračal obtožbe, si pridobil veliko privržencev po vsej Evropi in še naprej preučeval judovsko literaturo (leta 1517 je objavil delo De arte Cabbalistica). Papež je njegova dela leta 1520 obsodil, a je Reuchlin lahko nadaljeval z delom profesorja v Tübingenu in umrl (naravne smrti) v Stuttgartu leta 1522. Erazem je bil Reuchlinov velik občudovalec in v t. i. Reuchlinovi aferi se je postavil na njegovo stran, kakor priča tudi naslednji dialog. Kljub temu pa je bila Erazmova podpora nekoliko mlačna, saj je hotel Erazem, kot je zanj značilno, ostati čim bolj ob strani in se ni želel nedvoumno opredeliti.
Thomas More: Utopija (O verovanjih Utopijcev)
Authors: Božič Anja
Published: February 2017

Na otoku ni enotne vere in verovanja se razlikujejo celo znotraj posameznih mest. Nekateri po božje častijo sonce, nekateri luno, nekateri pa še kakšen drug planet. Obstajajo celo ljudje, ki poveličujejo človeka, slavnega zaradi njegove kreposti in dostojanstva, in ta zanje ni le eden od bogov, pač pa vrhovno božanstvo. Velika večina – in ti so daleč najrazumnejši – pa ne verjame ničesar od tega, ampak časti neko edino božanstvo, ki je nepoznano, večno, neizmerno, nepojmljivo in zunaj dosega človeškega razuma ter se ne v fizičnem, pač pa v duhovnem smislu razteza po vsem vesolju. Imenujejo ga Oče. Le njemu pripisujejo nastanek, razvoj, napredek, spreminjanje in konec vsega. Božanskih časti tako ne posvečajo nobenemu drugemu božanstvu.
Evripid: Ion (725‒1249)
Authors: Cajnko Mojca
Published: February 2017

Predstavljeni odlomek se začne na točki, ko se Krevza skupaj s starcem in služabnicami napoti k Apolonovemu templju, da bi izvedela prerokbo. V njem smo priča Krevzini bolečini, ko izve, da ne bo dobila otroka in da jo je Ksut izdal. Temu se pridruži še njena zgodba o Apolonovem posilstvu in izpostavitvi otroka. Starec ji predlaga maščevanje nad Ksutom in Ionom, Krevza pa se odloči zgolj za to, da bo poskusila odstraniti Iona. Njena spletka, da bi Iona zastrupila s kapljico Gorgonine krvi, je razkrita in Krevza je obsojena na smrt s kamenjanjem. Odlomek se zaključi s tožbo zbora ob smrtni obsodbi.