bluuebunny/crossref_metadata_2025 huggingface dataset:
EU energy taxation framework revision in the context of the green deal
Authors: Antón Antón Álvaro
Published: November 2022

The EU aims to reduce emissions by at least 55% by 2030. To achieve this, the European Commission launched proposals to introduce price signals through the modification or extension of the Emission Trading Scheme and the Energy Tax Directive. These instruments could have a negative impact on households and companies' competitiveness. This research focuses on the one hand, on the role of energy taxation in the achievement of climate objectives and budget stability. And, on the other, in analysing the role of taxation to develop compensatory measures so that the transition is efficient, socially fair and inclusive.
vídeo como herramienta para la educación artística
Authors: Gradín Carbajal Cristian , Ezquieta Llamas Iciar
Published: November 2022

El vídeo es un medio con gran potencial en el aula como integrador de diferentes contenidos curriculares, por su capacidad motivadora y como vehículo para trabajos cooperativos. Su utilización didáctica en el contexto español ha pasado por un largo recorrido en el que las problemáticas iniciales enfocadas hacia la tecnología han dejado paso a reflexiones más centradas en la alfabetización audiovisual y en su aplicación a metodologías activas, favorecidas por la digitalización y los nuevos dispositivos móviles.
Efficient synthesis of aziridinecyclooctanediol and 3-aminocyclooctanetriol
Authors: Salamci Emine , Lafzi Ayse Kilic
Published: November 2022

Cyclooctene endoperoxide was used as the key compound for the synthesis of aziridinecyclooctanediol and 3-aminocyclooctanetriol. Reduction of the cyclooctene endoperoxide, prepared by photooxygenation of cis,cis-1,3-cyclooctadiene, with zinc gave a cyclooctenediol and then benzylation of the hydroxy group yielded dibenzylated cyclooctene. Oxidation of the latter compound by OsO4/NMO followed by mesylation of the hydroxy group provided bis(benzyloxy)cyclooctane-1,2-diyl dimethanesulfonate. Reaction of the bis(benzyloxy)cyclooctane-1,2-diyl dimethanesulfonate with NaN3 gave 2-azido-3,8-bis(benzyloxy)cyclooctyl methanesulfonate. Reduction of the azide group and debenzylation to give an amine provided the new 3-aminocyclooctanetriol. Treatment of the 2-azido-3,8-bis(benzyloxy)cyclooctyl methanesulfonate with Zn/NH4Cl and debenzylation resulted in the target aziridinecyclooctanediol.
Contribution to a revision of Hoya (Apocynaceae: Asclepiadoideae) of Papuasia. Part II: eight new species, one new subspecies
Authors: Rodda M. , Simonsson N.
Published: November 2022

In the present paper we publish eight new species from New Guinea, H. domaensis, H. gauttierensis, H. liddleana, H. lucida, H. paradisea, H. pulleana, H. tarikuensis, and H. unirana, and one subspecies, H. krusenstierniana subsp.
laticorolla. Five taxa were first diagnosed based on specimens at the Leiden herbarium, one species is only known from a collection at Edinburgh and Lae herbaria, while three are based on recently collected specimens. Hoya leucantha, originally described from a specimen in bud,
has been identified among herbarium specimens and was also recently recollected. It is therefore fully described and illustrated for the first time.
Full-Day School as a Strengthening of Character Education Management for Students
Authors:   Fakultas Dakwah, Institut Pesantren Kh. Abdul Chalim Pacet Mojokerto, Indonesia, Rokhman Mauhibur , Munir Mochammad Misbakhul ,   Fakultas Tarbiyah, Institut Pesantren Kh. Abdul Chalim Pacet Mojokerto, Indonesia
Published: November 2022

This article aims to explain the management of character education through the development of full-day school management. This article is a literature review by analyzing the content of relevant books and journals. The results of the discussion of this article are that strengthening management in the implementation of full-day school is able to reduce student delinquency because students are guided and supervised in extracurricular activities or intracurricular activities. Families do not need to worry about the full-day school model because students are under supervision in accordance with the applicable strategic management. Good management can strengthen children's character when supported by exemplary methods. The application of full-day school is an alternative solution for the educational revolution to the problems that occur in the era of globalization. In the process of implementing full-day school, it can also strengthen the management of character education in schools.
An Analysis of Public Relations Management of IAIN Curup Bengkulu in Improving Digital Information Systems
Authors:   Institut Agama Islam Negeri Curup Bengkulu, Fathurrochman Irwan , Ariskawanti Eka ,   Universitas Islam Negeri Sunan Kalijaga Yogyakarta, Santosa Sedya ,   Universitas Islam Negeri Sunan Kalijaga Yoyakarta
Published: November 2022

The study was carried out to analyze public relations management at IAIN Curup Bengkulu in improving digital information systems; this topic is critical to discuss because it is to know the progress of educational institutions following the challenges of education 4.0. The type of research applied is descriptive qualitative, with the support of literature and news that shows the facts that occur in the field. Data collection was carried out using interviews, documentation, and observation. So from this technique, the researchers found data that aligned with the research topic. Public relations in tertiary institutions is a supporting wheel for quality progress in the education system. This is seen through his authority to establish connections with the community to various partners who follow the contribution of improvement in the quality of education. Public Relations of IAIN Curup Bengkulu in following the digital information system can be seen from the publication activities carried out through the Website, Youtube, and Social Media Applications. In addition, public relations efforts to improve the image of the institution can also be determined from activities: campus branding, agency marketing, and increasing cooperation networks with various partners. Digital branding needs to be improved by the public relations department of IAIN Curup Bengkulu to support the digital marketing program. Improvements must be considered, including providing media and more engaging content to prospective students. The study results show that the public relations service system at IAIN Curup Bengkulu has so far been beneficial in providing information and implementing educational marketing. The targeted information system is also primarily implemented via the internet. So this category shows that public relations activities have effectively moved information systems.
Toilet Sanitation Management in Supporting the Implementation of Public Services
Authors: Palar Novie R. A. , Lengkong Florence D. J. , Tulusan Femmy M.G. , Kolondam Helly F.
Published: November 2022

Good toilet sanitation management will not only provide added value in service satisfaction but is also a reflection of personal and environmental hygiene. However, toilet sanitation is one of the problems that people often complain about when they are in government offices. The availability of good toilet sanitation facilities has not been a concern of the government until now. This research was conducted using a qualitative design, collecting data directly or using google form and making direct observations of the condition of the toilet and its management. Data collection was also carried out using researchgate, google scholars and google scholars. By using systematic literature review technique data analysis and the use of primary data, it was found that the management of toilet sanitation in government offices was not good as seen from the quality of cleanliness and availability of facilities. There is no work unit available and responsible for toilet sanitation hygiene. The government can fix this by collaborating with third parties with a cleaning service workforce outsourcing system.
Uso de evidências científicas para a tomada de decisão diante da pandemia de COVID-19 : uma aproximação à atuação do Ministério da Saúde
Authors: Fernandez Michelle
Published: November 2022

Analisa a atuação do Ministério da Saúde durante a pandemia da covid-19, colocando luz sobre as decisões que ignoram evidências científicas robustas. Para isso, foram analisadas duas ações concretas do governo federal que demonstram a não consideração de evidências científicas robustas para atuar diante da covid-19: a opção por recomendações de enfrentamento à pandemia desconsiderando a de adoção das medidas não farmacológicas; e a adoção do tratamento precoce para covid-19.
Proteção ambiental baseada em evidências? Evolução institucional, planejamento e execução orçamentária no Ibama
Authors: Araújo Suely Mara Vaz Guimarães de
Published: November 2022

O objetivo deste capítulo é apresentar como a fiscalização ambiental e a prevenção e o combate dos incêndios florestais capitaneados pelo Ibama foram institucionalizados como políticas públicas concretas. Essa preocupação foi desdobrada em algumas reflexões: i) a evolução da autarquia, no sentido de usar informações técnicas e se apoiar em tecnologia da informação em seus processos decisórios sobre a fiscalização ambiental e a prevenção e combate dos incêndios florestais; ii) os principais aprendizados nesses temas; e iii) o quanto esses processos estão refletidos no planejamento e na execução orçamentária da autarquia.
O Uso de evidências científicas no enfrentamento à pandemia de covid-19 no Brasil : uma comparação das políticas dos governos estaduais
Authors: Moraes Rodrigo Fracalossi de
Published: November 2022

Este trabalho compara como governos estaduais no Brasil filtraram evidências da área de saúde e as incorporaram em políticas de enfrentamento à covid-19. O texto compara, em particular, o trabalho realizado no âmbito de arranjos institucionais de enfrentamento à pandemia criados pelos governos estaduais, com destaque para os 69 comitês científicos, gabinetes de crise ou equivalentes. O trabalho expande uma análise feita anteriormente em Palotti et al. (2021), os quais mediram o grau de proximidade entre o governo e a comunidade acadêmica durante a pandemia. Além dos objetivos de Palotti et al. (2021), analisa-se neste trabalho o escopo dos arranjos institucionais de enfrentamento à pandemia, sua interdisciplinaridade, o grau de transparência dos seus trabalhos e o seu grau de influência sobre políticas.
BÉZIER BASE EXTENDED ISOGEOMETRIC NUMERICAL METHOD FOR THERMO ELASTIC-PLASTIC ANALYSIS OF CRACK PROPAGATION IN CRACKED PLATE UNDER WELDING RESIDUAL STRESS AND THERMAL LOAD
Authors: Shoheib Mohammad M. , Shahrooi Shahram , Shishehsaz Mohammad , Hamzehei Mahdi
Published: November 2022

A new procedure in the field of Bézier base extended isogeometric method (XIGA) has been introduced to analyze the effect of welding residual stress and thermal load on crack propagation rate and fatigue life. This new procedure is based on the constitutive thermoelastic plastic equation. The main parts of this procedure are using the B´ezier base XIGA method to calculate the redistribution of welding residual stress due to crack growth and to compute the value of stress intensity factor (SIF) in the welding residual stress field. For this purpose, the grid points of Bézier elements (with C0-continuity) around the crack line and the crack tip are identified by the level set representation. Then, discontinuous enrichment functions are added to the isogeometric analysis approximation. Thus, this method does not require the re-meshing process. The results show that there is a good agreement between the results of proposed numerical method and the Hole-Drilling Strain-Gage method. The interaction integral method has been used to extract SIF. The effects of welding residual stress and thermal load on the SIF are considered using the superposition method. Also, the Walker equation has been modified to calculate the fatigue life caused by thermal loading and welding residual stress. The results display a good agreement between the proposed method and the finite element method. Due to the advantages of the Bézier based XIGA method, which eliminates parametric space and allows the precise addition of enrichment functions to the basis functions of cracked elements (crack line or crack tip), the obtained results are highly accurate that shows this method is effective for analyzing discontinuous problems.
SPECTRAL APPROXIMATION METHODS FOR FREDHOLM INTEGRAL EQUATIONS WITH NON-SMOOTH KERNELS
Authors: Allouch Chafik , Sbibih Driss , Tahrichi Mohamed
Published: November 2022

In this paper, polynomially based projection and modified projection methods for approximating the solution of Fredholm integral equations with a kernel of Green’s function type are studied. The projection is either an orthogonal projection or an interpolatory projection using Legendre polynomial basis. The orders of convergence of these methods and those of superconvergence of the iterated versions are analysed. A numerical example is given to illustrate the theoretical results.
NICMOS Kernel-phase Interferometry. I. Catalogue of Brown Dwarfs Observed in F110W and F170M
Authors: Factor Samuel M. , Kraus Adam L.
Published: November 2022

Filling out the dearth of detections between direct imaging and radial velocity surveys will test theories of planet formation and (sub)stellar binarity across the full range of semimajor axes, connecting formation of close- to wide-separation gas giants and substellar companions. Direct detection of close-in companions is notoriously difficult: coronagraphs and point-spread function subtraction techniques fail near the λ/D diffraction limit. We present a new faint companion detection pipeline called Argus that analyzes kernel phases, an interferometric observable analogous to closure phases from nonredundant aperture masking but utilizing the full unobscured telescope aperture. We demonstrate the pipeline, and the power of interferometry, by performing a companion search on the entire HST/NICMOS F110W and F170M image archive of 114 nearby brown dwarfs (observed in seven different programs). Our pipeline is able to detect companions down to flux ratios of ∼102 at half the classical diffraction limit. We discover no new companions, but recover and refine astrometry of 19 previous imaging companions (two with multiple epochs) and confirm two previous kernel-phase detections. We discuss the limitations of this technique with respect to nondetections of previously confirmed or proposed companions. We present contrast curves to enable population studies to leverage nondetections and to demonstrate the strength of this technique at separations inaccessible to classical imaging techniques. The binary fraction of our sample (

ϵ

b

=

14.4

−
3.0

+
4.7

%) is consistent with previous binary surveys, even with sensitivity to much tighter separation companions.
Two new Botryosphaeria (Botryosphaeriales, Botryosphaeriaceae) species in China
Authors: Sun Jing-E , Meng Chao-Rong , Phillips Alan J. L. , Wang Yong
Published: November 2022

Five ascomycetous strains were isolated from dead branches and leaves of Salix (Salicaceae) and Osmanthus fragrans (Oleaceae), respectively. BLAST searches with ITS sequences in GenBank suggested a high degree of similarity to Botryosphaeria dothidea. To accurately identify these strains, we further analysed their morphological characteristics of asci, ascospores, all conidiophore cells and conidia. Phylogenetic relationships, based on ITS, rpb2, tef1 and tub2 gene sequences, confirmed our strains represented two novel species, which are introduced here as B. salicicola and B. osmanthusespp. nov.
Design, synthesis and anti-diabetic activity of piperazine sulphonamide derivatives as dipeptidyl peptidase-4 inhibitors
Authors: Kalli Swarna Bharathi , Velmurugan V.
Published: November 2022

Type II diabetes (T2DM) is considered one of the most prevalent metabolic disorders in the world. It is known as insulin resistance and persistent hyperglycemia. Over the past decade, inhibition of the enzymatic dipeptidyl peptidase-4 (DPP-4) has indeed been demonstrated to be an efficient and safe intervention for type 2 diabetes. In order to develop innovative DPP-4 inhibitors, several in silico techniques including 3D-QSAR, molecular docking, in-silico toxicity has been performed to confirm a total of 18 novel piperazine and pyridine derivatives to be synthesized from many designed molecules. These molecules have indeed been docked onto the protein surface of the DPP-4 enzyme, and ADMET characteristics have also been generated in silico. The compounds were then developed and analysed using FT-IR. Then, these compounds were investigated for DPP-4 inhibition in vitro. The most promising compound 8h showed 27.32% inhibition at 10μmol L-1 concentration over DPP-4 so selected for further in-vivo anti-diabetic evaluation. Compound 8h decreased blood glucose excursion in a dose-dependent manner during the OGTT and STZ-induced glucose models in normal Albino Wistar rats. Low-dose streptozotocin-induced type 2 diabetes in Albino Wistar rats treated chronically for 21 days with compound 8h resulted in a reduction in serum glucose levels. This highlighted that 8h is a moderately strong and specific blockbuster molecule that can be structurally modified to boost its effectiveness and overall pharmacological profile as a DPP-4 inhibitor.
Is episodic memory change in aging associated with level of control processes and rate of control change? A 4-year longitudinal study
Authors: Guerrero Lina , Bouazzaoui Badiâa , Alibran Émilie , Isingrini Michel , Angel Lucie
Published: November 2022

En utilisant une approche longitudinale, nous avons exploré si le changement de la mémoire au cours de 4 ans est associé au niveau de contrôle de base et/ou au changement du niveau de contrôle sur la même période. Les participants ont été évalués deux fois à 4 ans d’intervalle avec une tâche de rappel indicé (mémoire épisodique) et une tâche de fluence verbale (contrôle). Un indice individuel de changement cognitif a été calculé pour chaque mesure. Les résultats ont montré que la mémoire et le contrôle ont diminué de façon significative au cours du temps et que l’indice de changement de la mémoire était corrélé significativement à l’indice de changement du contrôle mais pas au niveau de contrôle de base. Des analyses de régression indiquaient que 18 % de la variance de l’indice de changement de la mémoire était expliqué par l’indice de changement du contrôle. Ces résultats suggèrent que le niveau de changement de la mémoire au cours du temps varie en fonction du taux de changement du contrôle.
Ageism among psychology students: A comparative analysis between Belgium and Quebec (Canada)
Authors: Marquet Manon , T. Vallet Guillaume , Adam Stéphane , Missotten Pierre
Published: November 2022

Cette étude visait à évaluer les attitudes âgistes chez les étudiants en psychologie qui sont, potentiellement, de futurs professionnels de la santé. Cette étude visait également à examiner si les attitudes des étudiants québécois étaient plus favorables que les attitudes des étudiants belges. Le Québec est en effet engagé dans différentes initiatives favorables aux aînés qui peuvent promouvoir différents facteurs socio-économiques associés à des attitudes plus positives envers eux. Un total de 236 étudiants en psychologie (81 Belges et 155 Québécois) ont répondu à différents questionnaires mesurant leurs attitudes. Les étudiants québécois exprimaient en effet des attitudes globalement moins négatives envers les aînés. Étant donné que les attitudes négatives peuvent influencer le choix de travailler avec des personnes âgées et entraîner des conséquences néfastes dans le contexte de l’évaluation et de soin, nous discutons différentes pistes visant à améliorer ces attitudes.
Prendre soin de la pédopsychiatrie
Authors: Allione Marie
Published: November 2022

Qu’est-ce que la pédopsychiatrie devient sous la pression d’un libéralisme débridé, de changements sociétaux, en particulier de la place de l’enfant, d’une position antipsychanalytique primaire qui vise à remplacer toute forme de pensée par des protocoles ? Elle change de nature.
À la croisée des imaginaires : entre Orient et Occident
Authors: Colignon Martine
Published: November 2022

Au milieu des urgences de vie et de la douleur d’exister, s’invite une possibilité de créer un autre univers à la croisée des imaginaires. Peindre, dessiner impliquent pourtant une grande solitude et une bataille pour s’autoriser à mettre en forme de l’indicible, voire de l’innommable. Quel sens peut avoir celui de se trouver devant une feuille blanche, démunie, pour celle qui tente de retrouver un récit, son récit mais aussi celui de l’humanité ? Si écrire est devenu douloureux, le dessin permet un détour salutaire. Il invite la main à inventer d’autres chemins, retrouvant peu à peu celui de sa propre culture à la rencontre d’une autre, toutes deux auparavant antagonistes. Mots et images vont pouvoir se croiser, se rejoindre s’épouser et se supporter pour revenir à une expression, à la fois transculturelle et singulière.
Témoignage d’une AESH en quête de sens
Authors: Sacchelli Muriel , Astrée
Published: November 2022

Ce texte porte témoignage de l’évolution actuelle du métier méconnu d’ aesh dans un contexte néolibéral de démantèlement des services publics. Les réformes successives accentuent la précarité de leurs conditions d’exercice professionnel, constat qui va de pair avec le délitement de la qualité du travail d’accompagnement proposé aux élèves « en situation de handicap » qu’ils soutiennent dans leur scolarité en milieu dit ordinaire. Une professionnelle témoigne de cette attaque du sens, de l’engagement au quotidien et de l’éthique, à laquelle elle et ses pairs tentent de résister.
Penser les carrières bénévoles dans le monde associatif
Authors: Lebon Francis , Amrouche Ouezna , Binard Natacha , Dhorne Nathalie , Guérin Solenn , Haddou Zaineb , Hirsch Micaela , Lafarge Chloé , Mesmoul Alles , Pezzenati Laura
Published: November 2022

La notion de carrière invite à appréhender les différentes étapes d’accès et d’exercice d’un bénévolat et d’une profession. Elle permet de penser ensemble les prédispositions au militantisme, les formes différenciées d’engagement (professionnels, etc.) et leurs multiplicités tout au long de la vie. Comme l’a montré Maud Simonet, les relations entre les dimensions bénévoles, « volontaires », professionnelles et militantes du travail sont multiples dans un contexte de valorisation croissante du bénévolat et de l’engagement.
Paternal Postpartum Depression
Authors: Dillon Carrie , Embry Jennifer , Tavakoli Hamid R.
Published: November 2022

This is a case study of a 28-year-old man without former psychiatric history who presented to the emergency room for persistent thoughts of harming himself and his 2-month-old son for the past 1.5 months. He had also been experiencing anhedonia, feelings of guilt, decreased concentration, interest, sleep, and energy over the past month following the birth of his son. He was diagnosed with major depressive disorder and admitted to inpatient psychiatry ward to mitigate safety concerns. During his admission, his diagnosis was amended to postpartum depression based on onset of symptoms and association with the birth of his son. He was started on 10 mg vortioxetine and was discharged once suicidal and homicidal ideations resolved. He was provided outpatient services to include Cognitive Behavioral Therapy and continued medication management on vortioxetine. Outpatient treatment course resulted in complete resolution of symptoms.

[
Psychiatr Ann
. 2022;52(11):484–486.]
Transcranial Alternating Current Stimulation (tACS) for Major Depressive Disorder
Authors: Clancy Julie A. , Riddle Justin , Cassano Paolo , Frohlich Flavio
Published: November 2022

The 21st century has brought forth major advancements in device-based treatments for psychiatric disorders such as major depressive disorder (MDD). One of the most exciting technologies on the rise in this field is transcranial alternating current stimulation (tACS). The small but rapidly growing body of knowledge on tACS suggests that this wearable, low-cost, noninvasive neuromodulation method could provide a safe and effective alternative, or augmentation, to pharmacological interventions for MDD. While device parameters for treatment of MDD need refinement before this method is ready for standardized clinical use, we expect that tACS will make a significant impact on psychiatric treatment in the coming years.

[
Psychiatr Ann
. 2022;52(11):456–460.]
Transcranial Photobiomodulation (tPBM) for Major Depressive Disorder
Authors: McEachern Kayla , Cassano Paolo , Hurtado Aura , Caldieraro Marco Antonio
Published: November 2022

Major depressive disorder (MDD) is a leading cause of disability worldwide with current FDA approved treatments often not providing sustained relief to patients. Transcranial photobiomodulation (tPBM) with near-infrared light (NIR) is a neuromodulation technique that affects mitochondrial metabolism and has shown beneficial clinical outcomes in neurological and psychiatric disorders. At the cellular level tPBM causes various effects including increased oxygen consumption, increased adenosinetriphosphate (ATP) production, and short bursts of reactive oxygen species (ROS). Decreasing oxidative stress through lowering the secondary production of ROS, and increasing neural connectivity, through boosting of neurogenesis and synaptogenesis, as well as increasing energy metabolism are putative mechanisms for tPBM antidepressant effect. Preliminary clinical trials have shown that NIR tPBM is effective at decreasing symptoms of depression compared to sham, however optimal dosimetry is still uncertain. In some reports, the antidepressant effects of tPBM were sustained after treatment discontinuation. Choice of adequate treatment parameters is likely critical to the efficacy and tolerability of tPBM for MDD. General conclusions can be drawn to guide clinicians to the off-label use of tPBM for MDD in clinical practice.

[
Psychiatr Ann
. 2022;52(11):466–471.]
Cranial Electrotherapy Stimulation (CES) for Major Depressive Disorder
Authors: Vizcaino Fernando , Cassano Paolo , Hurtado Aura , Mischoulon David
Published: November 2022

Cranial electrotherapy stimulation (CES) is a noninvasive neuromodulation technique that has potential for treating several psychiatric diseases. This method consists of delivering bilateral low-intensity electrical current, via a pair of electrodes, to different anatomical targets around the head. This kind of stimulation is believed to interact with brain oscillation patterns, resulting in changes in connectivity of brain networks. CES has been observed to be a safe intervention with no serious side effects reported in randomized controlled trials. Unequivocal efficiency of CES has not been demonstrated for the treatment of major depressive disorder (MDD); however, some data suggest that CES could be an effective therapy for MDD, either as a standalone or in combination with pharmacological treatment and psychological therapy. CES devices are portable devices that do not required trained personnel to administer the treatment and therefore allow the patients to self-administer the treatment at home.

[
Psychiatr Ann
. 2022;52(11):461–465.]
Comparison Between the Wavefront-Optimized and Custom-Q Aspheric Ablation Profiles in Myopic Eyes With Two Different Q-targets: A Contralateral Eye Study
Authors: González-Cruces Timoteo , Villarrubia Alberto , Sánchez Ventosa Álvaro , Palacín Miranda Elisa , Castillo Eslava Rosa , Gomera Martinez Aurora , García Párrizas José Alberto , Torres Huelva Pablo , Sánchez-González Jose María , Cano-Ortiz Antonio
Published: November 2022

PURPOSE:

To compare two aspheric ablation profiles in myopic refractive surgery using different asphericity targets.

METHODS:

Patients underwent laser in situ keratomileusis (LASIK) with the WaveLight EX500 laser platform (Alcon, WaveLight Laser Technologie). Asymmetric surgery was performed, programming the wavefront-optimized (WFO) ablation profile in one eye and the custom-Q (CQ) profile in the contralateral eye. The patients were divided into two groups following a systematic randomization method. The Q-target programmed for the preoperative Q group was equal to the preoperative asphericity of the CQ profile, and for the −0.6 Q-target group, the Q-target was set to −0.6.

RESULTS:

The study included 100 patients (200 eyes). Both groups had comparable safety and efficacy indexes greater than 1. A similar oblate shift in postoperative asphericity was seen in both groups regardless of the ablation profile and programmed Q-target. Asphericity was 0.33 ± 0.34 and 0.35 ± 0.29 (
P
= .18) in the preoperative Q group and 0.26 ± 0.28 and 0.26 ± 0.27 (
P
= .89) in the −0.6 Q-target group for WFO and CQ, respectively. A lower spherical aberration was found with CQ compared to WFO when the Q-target was set to −0.6: 0.211 ± 0.121 versus 0.144 ± 0.114 (
P
< .01). However, no statistically significant differences were found when the preoperative Q-target was used.

CONCLUSIONS:

WFO and CQ treatments are similar in terms of refractive and visual outcomes. CQ offers greater control over the increase in positive spherical aberration after myopic refractive surgery, but it does not represent an advantage over WFO in the oblate shift in postoperative asphericity regardless of the Q-target programmed.

[
J Refract Surg
. 2022;38(11):698–707.]
Ectasia Risk Model: A Novel Method Without Cut-off Point Based on Artificial Intelligence Improves Detection of Higher-Risk Eyes
Authors: Santhiago Marcony R. , Araujo Daniella C. , Stival Larissa R. , Smadja David , Veloso Adriano A.
Published: November 2022

PURPOSE:

To develop a new ectasia risk model through artificial intelligence (AI) and machine learning, enabling the creation of an integrated method without a cut-off point per risk factor, and subsequently better at differentiating patients at higher risk of ectasia with normal topography.

METHODS:

This comparative case-control study included 339 eyes with normal preoperative topography, with 65 eyes that developed ectasia after laser in situ keratomileusis (ectasia group) and 274 eyes that did not develop ectasia (control group). The AI model used known risk factors to engineer 14 additional ones, totaling 20 features. In this methodology, no variable is used in isolation because its cut-off point is never considered. All separation between cases and controls is made through the interaction detected by the machine learning model that gathers the variables considered relevant. The ability to correctly separate ectatic cases identified as high risk, ectatic cases wrongly classified as low risk, and controls were illustrated by the diagram t-distributed stochastic neighbor embedding (t-SNE).

RESULTS:

Only two original variables (percent tissue altered and corneal thickness) and two derived from the feature engineering process (derivative percent tissue altered and age weighted value) were selected by the final AI model (ie, best performing AI-based model to separate patients at higher risk). The t-SNE visualization demonstrated the greater ability to differentiate between patients considered at risk by the AI-based model, without a cut-off point, compared to all other methods used alone (
P
< .0001).

CONCLUSIONS:

This study describes a new AI-based model that integrates different risk factors without a cut-off point, increasing the number of cases correctly identified as at higher risk.

[
J Refract Surg
. 2022;38(11):716–724.]
Changes in Light Disturbance Analyzer Evaluation in SMILE for High Myopia and Astigmatism
Authors: Reinstein Dan Z. , Archer Timothy J. , González-Méijome José Manuel , Vida Ryan S. , Gupta Ruchi
Published: November 2022

PURPOSE:

To study the objective change in light disturbance around a glare source using the Light Disturbance Analyzer (LDA) (Binarytarget Lda) and correlate this with the validated subjective quality of vision (QoV) questionnaire in small incision lenticule extraction (SMILE) for high compound myopic astigmatism.

METHODS:

This was a prospective study recruiting 114 patients undergoing SMILE with attempted spherical equivalent refraction (SEQ) correction from −9.00 to −13.00 diopters (D), and cylinder up to 5.00 D. The LDA was used before and 3 and 12 months after surgery to evaluate the Light Disturbance Area, Light Disturbance Index, Best Fit Circle Radius, and Best Fit Circle Irregularity. Patients completed the Rasch-validated QoV questionnaire before and 12 months after surgery. Correlation analysis was performed between the LDA parameters and the QoV frequency, severity, and bothersomeness for halos and starbursts.

RESULTS:

At 12 months, there was a non-statistically signifcant change of 11.9% for Light Disturbance Area and Light Disturbance Index and 6.5% for Best Fit Circle Radius. There was an increase of 81.9% for Best Fit Circle Irregularity (
P
= .017). Light Disturbance Area, Light Disturbance Index, and Best Fit Circle Radius correlated with bothersomeness for QoV halos, and with frequency, severity and bothersomeness for QoV star-bursts (P < .05), albeit with a low correlation coefficient (
R
2
< 0.13). There was no correlation between increase in Best Fit Circle Irregularity and the halo and starburst scores from the QoV questionnaire.

CONCLUSIONS:

LDA Best Fit Circle Irregularity was found to increase following high myopic SMILE. Other LDA parameters appeared to increase, but a much larger sample would be required to find statistical significance. The change in LDA parameters was only weakly correlated with QoV halo and starburst metrics, representing the wide variation in inter-subject perception.

[
J Refract Surg
. 2022;38(11):725–732.]
A weakly supervised learning-based segmentation network for dental diseases
Authors: Li Yue , Jin Hongmei , Li Zhanli
Published: November 2022

With the development of deep learning, medical image segmentation has become a promising technique for computer-aided medical diagnosis. However, the supervised training of the algorithm relies on a large amount of labeled data, and the private dataset bias generally exists in previous research, which seriously affects the algorithm's performance. In order to alleviate this problem and improve the robustness and generalization of the model, this paper proposes an end-to-end weakly supervised semantic segmentation network to learn and infer mappings. Firstly, an attention compensation mechanism (ACM) aggregating the class activation map (CAM) is designed to learn complementarily. Then the conditional random field (CRF) is introduced to prune the foreground and background regions. Finally, the obtained high-confidence regions are used as pseudo labels for the segmentation branch to train and optimize using a joint loss function. Our model achieves a Mean Intersection over Union (MIoU) score of 62.84% in the segmentation task, which is an effective improvement of 11.18% compared to the previous network for segmenting dental diseases. Moreover, we further verify that our model has higher robustness to dataset bias by improved localization mechanism (CAM). The research shows that our proposed approach improves the accuracy and robustness of dental disease identification.
Pharmacological evidence for the possible involvement of the NMDA receptor pathway in the anticonvulsant effect of tramadol in mice
Authors: Zahir Mazyar , Rashidian Amir , Hoseini Mohsen , Akbarian Reyhaneh , Chamanara Mohsen
Published: November 2022

Background

Previous studies have shown controversial results regarding the pro- or anticonvulsant effects of tramadol. Additionally, the underlying mechanism of seizure induction or alleviation by tramadol has not been fully understood. In the current study, the effects of tramadol on pentylenetetrazole (PTZ)-induced seizure and the possible involvement of the N-methyl-D-aspartate (NMDA) pathway were assessed in mice.

Methods

Male Naval Medical Research Institute (NMRI) mice were treated with intravenous infusion of PTZ in order to induce clonic seizures and determine seizure threshold. Tramadol was injected intraperitoneally (0.1–150 mg/kg) 30 minutes prior to elicitation of seizures. The possible effects of intraperitoneal injections of NMDA receptor antagonists, ketamine (0.5 mg/kg) and MK-801 (0.5 mg/kg) on the anticonvulsant property of tramadol were investigated subsequently.

Results

Tramadol (1–100 mg/kg) increased PTZ-induced seizure threshold in a dose-dependent, time-independent manner, with optimal anticonvulsant effect at a dose of 100 mg/kg. Acute administration of either ketamine (0.5 mg/kg) or MK-801 (0.5 mg/kg) potentiated the anticonvulsant effect of a subeffective dose of tramadol (0.3 mg/kg).

Conclusion

These results suggest a possible role of the NMDA pathway in the anticonvulsant effect of tramadol.
Encadrer l’archéologie préventive en Afrique centrale : l’expérience camerounaise
Authors: Nlend Pascal Nlend
Published: November 2022

L’archéologie préventive intègre progressivement les projets d’aménagement du territoire au Cameroun. Malgré cette prise en compte, l’on observe encore une méconnaissance du cadre réglementaire par les décideurs, les maîtres d’ouvrage, voire les archéologues. Il est opportun, à présent, de renforcer la sensibilisation auprès des différents intervenants au sujet du contexte légal de l’archéologie, dont on présente ici les grandes lignes, aux niveaux national (Cameroun) et international. Le constat de la disparité des procédures d’intervention nécessite, selon les experts, la mise en place d’une harmonisation afin que la production des divers documents d’expertise soit normalisée. Cela concerne toutes les phases d’un projet, à savoir avant la construction, pendant l’aménagement et après les travaux.
“Tu lengua hace de mi cuerpo un país entero” : Érotisme et revendications poé(li)tiques chez Irma Pineda
Authors: Demay Clémence
Published: November 2022

À partir de l’écriture du désir et de l’érotisme, le recueil de poésie Rojo Deseo, de la poétesse zapotèque Irma Pineda, interroge les frontières constituées par les représentations coloniales et patriarcales qui fétichisent la tehuana et la métisse1 : il s’agit de déconstruire les mécanismes de subordination des corps féminins aux corps masculins, à l’extérieur de la communauté mais aussi à l’intérieur. Reconnaissant l’intersectionnalité des luttes contre le racisme, le sexisme, et l’hétéronormativité, l’érotisme devient alors politique : la voix poétique reconquière l’espace de son corps pour en faire un territoire à soi2, d’où exercer sa souveraineté et sa subjectivité. Nourri de la culture et des jeux de mots zapotèques, le jeu érotique apparaît au cœur de l’écriture bilingue et des gravures qui l’accompagnent : c’est ainsi un érotisme ethnique et queer qui s’affirme et met en évidence la fécondité de l’espace frontalier, comme lieu d’une définition d’une nouvelle relation à l’Autre, faite de réciprocité et non d’effacement.
Homoérotisme lesbien et rénovation du champ littéraire dans les années 30 : Victoria Ocampo, Virginia Woolf et l’effet papillon
Authors: Courau Thérèse
Published: November 2022

L’histoire littéraire s’est peu intéressée aux enjeux de l’homoérotisme dans l’émergence de réseaux féministes et lesbiens en littérature dans les années 30, notamment au niveau international. Dans cet article, nous envisagerons cette question à partir d’une relecture queer et intersectionnelle de la relation entre l’écrivaine et éditrice argentine Victoria Ocampo et l’autrice britannique Virginia Woolf. L’objectif de ce travail est de contribuer à la relecture du canon lesbien, in/visibilisé dans son « placard de verre » depuis l’articulation entre l’homosocialité féminine et la construction d’un positionnement sexo-dissident. Nous faisons l’hypothèse que l’homoérotisme dans les relations entre autrices – qui a souvent été relégué au rang d’anecdote insignifiante sur le plan politico-culturel – a, à la manière de « l’effet papillon », participé des bouleversements structurels dans le champ littéraire de cette époque.
Digital Education, Learning Management Systems
Authors: Setiana Desi , Besar Norainna , Susanto Alifya Kayla Shafa , Yie Leu Fang , Susanto Heru , Subramanian Ulaganathan
Published: November 2022

Digital education, which is currently trending, creates a structural system that manages the learning and teaching process. The aim of this study is to reveal that learning management systems are part of the e-learning paradigm where it contributes to digital education. Online students are more prone to loneliness due to isolation, and the number of supported majors are very limited as e-learning is more suitable for theory-based courses, less practical. The result is promising. It is challenging to find flaws in LMS, and there is almost zero doubt that it plays a huge importance and will continue to benefit the workplace of today and beyond. While the mass adoption of LMS by people in all professions of life is inevitable, it still faces some short-term hurdles that need to be solved before this vision can come to fruition. Time efficiency is also questionable due to the learning curve that non-tech savvy individuals have to face before being able to fully utilize an LMS.
Using Applicable E-Learning Principles to Promote Effectiveness and Quality in the Digital Era
Authors: Mautso Kenneth , Goosen Leila
Published: November 2022

The purpose of the research reported on in this chapter was to determine to what extent a particular educational institution was using applicable e-learning principles to promote effectiveness and quality in the digital era and to find ways to assist the school toward becoming a more inclusive and resilient e-school. Schools are doing their best to improve learning techniques and are implementing different approaches and methods to see how best they can deliver effective and quality educational courses. It is vital that there not only should be a change in resources or techniques, but it is equally important to have a change in mindset whenever one plans to implement anything new. Thinking should evolve, and this is what e-learning seeks to achieve: maximum results cannot be achieved unless all processes, perceptions, and resources have been exhausted.
Performance Optimization of Multi-Hop Routing Protocols With Clustering-Based Hybrid Networking Architecture in Mobile Adhoc Cloud Networks
Authors: Srivastava Deepak , Kumar Ajay , Mishra Anupama , Arya Varsa , Almomani Ammar , Hsu Ching Hsien , Santaniello Domenico
Published: November 2022

Mobile networks, in particular, are composed of wireless cellular communication nodes (MANET). Communication between these mobile nodes is not under centric systems. MANET is a network of randomly traveling nodes that self-configure and self-organize. Routing is a fundamental topic of MANET, and performance analysis of routing protocols is the focus of this study. AODV, DSR, and WRP are three routing protocols that are compared in this article. Glomosim will be used for simulation. The throughput, average end-to-end latency, and packet delivery ratio of various routing systems are all examined. Two scenarios depending on mobility and node density are considered in this research. As node density rises, PDR and throughput rise with it. Low node density resulted in the shortest delay. AODV has a higher packet delivery ratio and throughput in both scenarios, while WRP has the shortest delay. The authors also analyzed the average energy consumption with a best routing protocol that was decided by the result and conclude the efficiency of the ad-hoc network.
Information Privacy Assimilation
Authors: Halder Suhasish , Attili V. S. Prakash , Gupta Vivek
Published: November 2022

This paper proposes a framework to understand organizations' perspectives while safeguarding customers' information privacy. Following a detailed literature review, a broad conceptual model was developed to build a theory based on a multi-site, multi-case study approach. The current manuscript treats information privacy as distinct from information security. From an organizational standpoint, this research reveals that legal policy, technology, and industry standards drive privacy assimilation. At a detailed level, adherence to compliance, competitive best practices, and data management controls significantly impact an organization's opportunistic perspective, resulting in higher-order assimilation (infusion) of organizational privacy practices. Resistance to compliance, investment cost, and reactive approach results in lower-order assimilation (adaptation) of organizational privacy practices. This study delivers practical implications related to how businesses perceive privacy practices while maintaining the right balance of privacy risks and opportunities.
Perceived Website Efficacy for Life Insurance Companies
Authors: Kaur Anupriya
Published: November 2022

Given the proliferation of websites which act as digital channels for life insurance companies, a competitive situation has emerged with each vying for the web user's attention and patronage. Web efficacy is vital for creating an impressive online experience and gaining customer patronage. To facilitate the understanding of website managers on specific aspects which matter the most to customers, this study employs the best-worst method to evaluate the importance of various criteria employed by the web users to assess these digital options. Additionally, using four life insurance websites (LIC, SBI Life, HDFC Life Insurance, and Max Life Insurance) as alternatives, the study helps illustrate the competitive position of the websites based on key criteria: trust, visual appeal, innovativeness, information fit-to-task, tailored information, response time, intuitive operations, and relative advantage. The results of this study are easily interpretable and can provide key insights on the specific attributes in a comparative manner for website administrators and managers.
Trends and Research on the Teaching and Learning of Mathematics in Higher Education Institutions Through Mobile Learning
Authors: Niño Francisco , Gómez Sergio
Published: November 2022

In the last decade, the use of mobile devices has been intensified at all educational levels. They have recently been included in the design of strategies and methodologies that contribute to mathematics education, especially in the resolution of mathematical problems. In this research, a systematic review is carried out on the use of mobile devices in the teaching and learning of mathematics in higher education institutions, with the purpose of identifying advantages, limitations, effectiveness, trends, and characteristics that have been presented in the last 10 years. Thirty articles were selected between 2011 and 2021 in 15 indexed journals with three specialized on mobile learning. The insights found allow us to see the current state of the use of mobile learning in the teaching and learning of mathematics in higher education institutions and evolution in new research in mathematics educational scenarios.
QSAR Regression Models for Predicting the Activity of Inhibitors of Staphylococcus Epidermidis
Authors: Desai Sharav A.
Published: November 2022

Staphylococcus epidermidis is a common symbiont bacteria, and these are common causes of nosocomial infections. The QSAR model for the identification of inhibitors against Staphylococcus epidermidis is developed. A database of around 600 compounds with known inhibitory zone values was collected. Descriptors representing structural and functional properties were calculated using Alvadesc v.1.02. This database was curated using feature selection and extraction procedures. The model was developed using four different machine learning algorithms on a training set called multiple linear regression, support vector regression, random forest regression, and random tree regression. The model performance has been assessed by traditional metrics including Pearson's correlation coefficient, coefficient of determination, mean absolute error, and root mean square deviation. The author also has performed external validation, cross-validation, and y-randomization test. Models with reasonably good performance were built and can be used for the virtual screening of inhibitors.