bluuebunny/crossref_metadata_2025 huggingface dataset:
A Cloned Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine, PHV01, Protects Guinea Pigs from Lethal Marburg Virus Disease
Authors: Zhu Wenjun , Liu Guodong , Cao Wenguang , He Shihua , Leung Anders , Ströher Ute , Fairchild Michael J. , Nichols Rick , Crowell Joseph , Fusco Joan , Banadyga Logan
Published: June 2022

Marburg virus (MARV) is a negative-sense, single-stranded RNA virus that belongs to the Filoviridae family. Despite having caused numerous outbreaks of severe hemorrhagic fever with high case fatality rates, there are still no clinically approved therapeutics or vaccines to treat or prevent MARV disease. Recombinant vesicular stomatitis viruses (rVSVs) expressing heterologous viral glycoproteins have shown remarkable promise as live-attenuated vaccine vectors, with an rVSV-based Ebola virus vaccine having received regulatory approval in the United States and numerous other countries. Analogous rVSV vaccine vectors have also been developed for MARV and have shown efficacy in several preclinical studies conducted in nonhuman primates. Here, we used a guinea pig model to confirm the protective efficacy of a cloned, rVSV-based candidate vaccine, termed PHV01, expressing the MARV variant Angola glycoprotein. Our results demonstrated that a single dose (2 × 106 PFU) of vaccine administered 28 days prior to challenge with a uniformly lethal dose of guinea-pig-adapted MARV variant Angola provided complete protection from death and disease. Moreover, protection was robust, with as little as 200 PFU of vaccine conferring significant protection. Not only does this study highlight the potential predictive value of the guinea pig model in the evaluation of MARV countermeasures, but it also demonstrates consistent and reproducible protection afforded by a clonal vaccine candidate. Indeed, this study identifies PHV01 as a suitable vaccine candidate for advanced development.
Successful Treatment of Vertebral Osteosarcoma in a Cat Using Marginal Surgical Excision and Chemotherapy
Authors: Giuliano Antonio , De Busscher Virginie , Lu Diane D. A. , Ng Karen W. L. , Beatty Julia A.
Published: June 2022

A three-year-old male neutered Norwegian Forest cat was referred for bilateral ambulatory paraparesis and spinal pain. On magnetic resonance imaging (MRI), a mass involving the right epaxial muscles with vertebral canal invasion and causing marked extradural spinal cord compression was identified. At surgery, the mass was debulked and a right hemilaminectomy was performed. Histopathology was diagnostic of fibroblastic osteosarcoma. Residual osteolytic lesions of the osteosarcoma were present at the level of the spinous process of the second lumbar vertebra. Four cycles of adjuvant doxorubicin chemotherapy were administered followed by oral toceranib phosphate. Neurological signs improved gradually over weeks to months and the lesion in the spinous process was no longer visible on radiographs. At one year from diagnosis, an MRI of the T3-L3 (3rd thoracic vertebra to the 3rd lumbar vertebra) spinal region and a whole-body computer tomography (CT) scan found no evidence of the osteosarcoma in the spine or of any metastasis. All medications were stopped and, at the time of writing 16 months later, the patient is neurologically normal with no signs of cancer recurrence. This is the first case report documenting the complete resolution of vertebral osteosarcoma lesions after treatment with doxorubicin followed by toceranib phosphate. The treatment also prevented tumor recurrence and was associated with an exceptionally long-term survival time.
IbM USAHA TOKO TRADISIONAL DAN UNIT PERTOKOAN KOPERASI DI KABUPATEN JEPARA
Authors: Nahar Aida - , Aminnudin Moch -
Published: June 2022

The presence of modern stores has led to the climate of unfair competition harmful traditional stores. The existence of a minimarket can turn off 20-50 small grocery stores, while a supermarket can be lethal up to 200 grocery stores, while hypermarkets and 500 grocery stores. minimarket establishment, in a radius of 500 meters will result in a decline in income of up to 57.92 percent. At a radius of 1 km to 30 percent. Defeat competing with traditional stores because of low competitiveness. This situation experienced by both partners, traditional shop "Darul Ulum" and Toko Abdul Khamid.These service activities seek to address the problem of lack of competitiveness in the form of partners, and exacerbated by the low-performance service standards for record-keeping and accounting system is still manual. Therefore, the outcome of devotion is a solution to the problem. Such as 1) program to improve competitiveness, 2) development of accounting information systems. The approach used is a method of interactive participation, in which both partners will play a role in the analysis process for planning activities and the strengthening of internal organization.The method of implementation program to improve competitiveness, carried out in phases: 1) a SWOT Analysis, 2) Guarantee of perception and deal program, 3) Modernization store, 4) Training service standards, 5) Training governance and SOP, 6) creation of SOP shops, 7 ) Implementation and mentoring. Program information systems development shops, stages: 1) analysis of requirements and design of information systems, 2) identification and preparation of database product items and members or prospective members, 3) Making accounting software, 4) Application of accounting information systems, 5) training information system accounting, 6) special units of cooperative stores, to disseminate the members, administrators and managers of cooperatives, 7) Implementation and facilitation of the use of the system. As quality assurance efforts in the implementation of each of the partners will be accompanied by two students.
Pendampingan Bahasa Perancis Pariwisata Bagi Pemandu Wisata di Kabupaten Pangandaran – Jawa Barat
Authors: Racmadhany Ariessa , Darmawangsa Dante , Sopiawati Iis , Sunendar Dadang , Mulyadi Yadi
Published: June 2022

This French language training is based on the limited ability of foreign languages other than English, namely French for tour guides in Pangandaran Regency. Until now there has been no formal education institution that provides French language in Pangandaran Regency, even though this area is an important tourist destination for West Java which is visited by many french tourists in 2019 (see Nurroni, 2019). Meanwhile, according to BAPPEDA West Java Provincial Government, this regency will become an international class tourist destination in 2021-2025. Departing from this goal, this service program provides training in French Tourism which can provide insight into french language skill to tour guides in Pangandaran Regency so that it will lead to improving the quality of their languages. This service aims to 1) provide French Tourism training for tour guides in Pangandaran Regency; 2) conduct a simulation of the jeux de rôles-actes de parole technique (role play-technical speaking acts) based on local wisdom of Pangandaran Regency. Based on the results of the training, tour guides in Pangandaran Regency are familiar with the French alphabet and numbers, are able to carry out simple conversations, and introduce tourist objects in Pangandaran in a simple manner
أسلوب خطاب الله للنُّخبة المؤمنين في القرآن الكريم
Authors: EİD Nezam Alddin , MÜEZZİN Ahmet Derviş
Published: June 2022

حظي أسلوب الخطاب في القرآن الكريم اهتمام العلماء والبلاغيين قديمًا وحديثًا؛ وذلك لما يحتويه من جمالٍ في المبنى، ودقّةٍ في المعنى، وتنوّع في التعبير، وقد لاحظنا من خلال استقرائنا لآيات القرآن الكريم هذا التنوّع، وتغيّر صيغ النداء والموضوعات بما يتناسب مع الـمُخَاطَبِ ومكانته. وقد هدفت هذه الدراسة الكشف عن أسلوب خطاب الله عزَّ وجلَّ للنُّخبة من الناس على اختلافِ مكاناتهم، وبيان معنى الخطاب والنُّخبة عند القدماء والمحدثين، مع ذكر الفرق بين مفهوم الخطاب العام والخطاب القرآني، وذكرنا أيضًا أنواع خطاب النُّخبة، وقد قسّمناها إلى ثلاثة أنواع: خطاب للأنبياء وللصالحين و للمؤمنين، وسردنا الصيغ التي وردت فيها تلك الخطابات، والفرق بين أسلوب مخاطبة الأنبياء والرسل وأسلوب مخاطبة نبينا محمد ﷺ، مُستخدمين المنهج الوصفي في استقراء أنواع النُّخبة التي استهدفها الخطاب الربّاني، والصيغ التي جاءت عليها، والمنهج التحليلي في دراسة بعض السّمات والخصائص التي يتميز بها أسلوب خطاب النُّخبة عبر الوقوف على بعض الآيات القرآنية تحليلًا وتطبيقًا، وأشرنا إلى مدى جمالية هذا الاختصاص وبديعه، وأسباب تنوّع الخطاب الإلهي لعباده.
تحليل وتقويم كتاب اللغة العربية المقرر على طلاب الصف السابع في مدارس الأئمة والخطباء في ضوء معايير مقترحة
Authors: ALI Ahmed Hassan
Published: June 2022

هدف البحث إلى تحليل وتقويم كتاب اللغة العربية المقرر على طلاب الصف السابع في مدارس الأئمة والخطباء التركية في ضوء معايير مقترحة؛ وذلك من أجل تحديد نقاط القوة فيتم تأكيدها وتنميتها، وتحديد جوانب القصور فيتم تقويمها وتلافيها في الطبعات التالية. ولتحقيق هدف البحث صمم الباحث أداة تحليل محتوى تكونت من مائتي معيار، وتم تصنيف هذه المعايير في عشرة مجالات رئيسة، وقد استخدم الباحث المنهج الوصفي التحليلي للحصول على نتائج كمية وكيفية دقيقة، وقد أظهرت نتائج التحليل توافر عدد كبير من المعايير التي تم التحليل في ضوئها، كما أظهرت بعض أوجه القصور في الكتاب. وفي ضوء هذه النتائج قدم البحث مجموعة من التوصيات التي تسهم في تقويم وعلاج أوجه القصور التي كشف عنها التحليل.
Learners’ Perceptions towards Dual-Coding in Hypermedia Environments: Listening Texts, Keywords, Visuals and Captions
Authors: TÜREL Vehbi
Published: June 2022

This study investigated 57 participants’ (N= 57) perceptions towards dual-coding in design of audio-only listening texts (i.e. re-provision of the same audio-only listening texts in the form of audio-only listening texts + keywords or supplementary contextual visuals + keywords at non-initial phases of the while-listening stage, and audio-only listening texts + (full) captions at final listening stage) in adaptable hypermedia environments (HEs) for foreign language learning (FLL). The study also aimed to find out whether there were any differences between their perceptions in terms of participants’ characteristics as well as between their perceptions towards dual-coding. The study was both quantitative and qualitative in nature. The results of the quantitative data were analysed with SPSS (i.e. Mean, Std. Deviation, ANOVA, Pearson Correlation Test). The results revealed that the participants were overwhelmingly in favour of the use of dual-coding in design of audio-only listening texts in HEs for FLL. The majority believed that not only did the dual-coding in design of audio-only listening texts benefit them in different ways, but it also contributed to the enhancement of their learning. Moreover, the results of the quantitative data revealed that there were some significant differences between the participants’ perceptions.
PENGARUH KONSERVATISME AKUNTANSI, INVESTMENT OPPORTUNITY SET, DAN FAKTOR LAINNYA TERHADAP KUALITAS LABA
Authors: Maulia Riztia , Handojo Irwanto
Published: June 2022

This study aims to obtain empirical evidence and analyze factors that affect earnings quality. The independent variables in this study are institutional ownership, independent commissioner, accounting conservatism, investment opportunity set, capital structure, and company size. Meanwhile the dependent variable in this study is earnings quality. The company used in this research manufacturing companies that listed on the Indonesian Stock Exchange (IDX) from 2018 to 2020. This research using purposive sampling method where there are 376 company year data. This research using multiple regression method to examine the effect of independent variables and dependent variable earnings quality. The result of this study show that accounting conservatism and company size has an effect on earnings quality. Meanwhile institutional ownership, independent commissioner, investment opportunity set and capital structure has no effect on earnings quality.
THE EFFECT OF EARNINGS PERSISTENCE, SYSTEMATIC RISK, AND CONSERVATISM ON EARNINGS RESPONSE COEFFICIENT
Authors: Suhandi Noviola , Sutrisno Paulina
Published: June 2022

The purpose of this study is to empirically examine the factors that affect the earnings response coefficient. This study uses independent variables earnings persistence, company growth, systematic risk, capital structure, profitability, conservatism and earnings response coefficient (ERC) as the dependent variable. The study was conducted on 43 manufacturing companies listed on the Indonesia Stock Exchange from 2017 to 2019 which were obtained using purposive sampling method. Samples and data were tested and analyzed using multiple regression methods. The results of this study indicate that company growth has a negative effect on earnings response coefficient. While earnings persistence, systematic risk, capital structure, profitability, and conservatism have no effect on earnings response coefficient.
Generalizability Theory and Its Application to Institutional Research
Authors: Sturgis Paul W. , Marchand Leslie , Miller M. David , Xu Wei , Castiglioni Analia
Published: June 2022

This article introduces generalizability theory (G-theory) to institutional research and assessment practitioners, and explains how it can be utilized to evaluate the reliability of assessment procedures in order to improve student learning outcomes. The fundamental concepts associated with G-theory are briefly discussed, followed by a discussion of the software needed to conduct a generalizability study (G-study) analysis. The article then presents a case study of a G-study analysis; this case study was conducted in order to evaluate the generalizability and dependability of an exam that third-year medical school students complete. The conclusion discusses several situations that institutional research and assessment practitioners are likely to encounter where G-theory can be used to evaluate and improve their assessment procedures in pursuit of improving student learning outcomes.
Tomamaeite Cu3Pt in native osmium from river sediments in
the Nizhnie Sergi Region, Central Urals
Authors: Sharygin V.V. , Mikhailov I.G.
Published: June 2022

The article is devoted to tomamaeite Cu3Pt from inclusions in a native osmium grain from alluvial river sediments in the Nizhnie Sergi region, Sverdlovsk oblast. It is the fourth fnding of this mineral in the Urals. In addition to tomamaeite, native osmium Os0.36Ir0.33Ru0.31 contains the inclusions of digenite (or, possible, roxbyite), millerite, Fe-Ni-Pt alloy, an unidentifed Pd mineral, magnesiohornblendite, and low-Ca pyroxene. In composition, tomamaeite is close to ideal formula Cu3Pt and contains minor amounts of (wt. %) Pd (up to 2.0), Ir (up to 1.7), Ru and Ni (up to 0.6), and Fe (up to 0.2). In addition to native osmium, two grains of native ruthenium Ru0.54Os0.23Ir0.23 and Ru0.40Os0.31Ir0.29 are found in sediments. Our data suggest that PGE minerals in river sediments could be sourced from mafc-ultramafc massifs located in the Nizhnie Sergi area. The formation of tomamaeite and coexisted minerals is related to the process of postmagmatic transformation of the primary PGE mineral assemblage, probably, during serpentinization of ultramafc rocks.
A sequence of formation of «uranpyrochlore» and fluorocalciopyrochlore in alkali pegmatites from the Vishnevye Mountains, South Urals
Authors: Popova V.I. , Popov V.A. , Blinov I.A. , Kotlyarov V.A. , Lebedeva S.M.
Published: June 2022

The sequence of formation of pyrochlore crystals of various morphology and composition is considered in an aggregate with ilmenite and feldspar of nepheline-feldspar pegmatite at Mt. Dolgaya (Vish-nevye Mountains, South Urals): altered yellowish green «uranium pyrochlore» with a UO3 content of 7.62– 42.44 wt. % in different parts of the crystal, and also fuorocalciopyrochlore, fersmite, and associated minerals. The alteration of «uranpyrochlore» includes fersmitization and silicifcation in contrast to relatively late fuo-rocalciopyrochlore and fersmite. The compositions and Raman spectra of altered «uranpyrochlore» and later fuorocalciopyrochlore are given.
REE and Th minerals in the metasandstones of the Udokan basin (Russia)
Authors: Belogub E.V. , Novoselov K.A. , Shilovskikh V.V. , Blinov I.A. , Palenova E.E.
Published: June 2022

Based on ICP-MS, optical and electron microscopy, and electron back-scatter diffraction data, the paper considers the distribution and mode of occurrence of REE and Th in metasandstones of the Lower Proterozoic Sakukan Formation, which host mineralization of the Udokan and Unkur copper sandstone deposits. The REE and Th contents increase in the layers enriched in iron oxides and minerals of natural heavy concentrate relatively to the background metasandstones. Detrital allanite is the major REE mineral, which occurs in layers enriched in iron oxides together with authigenic allanite, monazite, and unidentifed Ca and REE carbonates. Thorium is concentrated in an authigenic silicate (thorite or thorogummite), which contains a signifcant amount of Fe, Ca, Al, and Cu and microinclusions of Cu and Pb sulfdes and barite. The diagenetic formation of authigenic REE and Th minerals is suggested as a result of desorption of these elements from siliceous-ferruginous gel-like sediments formed in river deltas and the wave-cut zone of the Proterozoic Sea.
Análisis e identificación de las modalidades de formación de mayor impacto en el aprendizaje de los profesores universitarios
Authors: Martínez Milgian
Published: June 2022

There are several training modalities through which the professional development of university teaching staff can be guided; however, there are some that generate greater impact than others on learning and teaching practices. In this sense, the objective of this article is precisely to identify those modalities with the greatest impact based on a review of what different authors propose in this regard, being aware that not only the modalities affect the ability of a teacher to apply the learning that he obtains, but there may be a set of factors that favor or hinder this acquisition. Likewise, although there are various ways of classifying these modalities, for the purposes of the article we consider two main types, depending on the degree of participation that teachers may have during their training: individual and collective modalities. It was identified that mentoring, accompaniment, learning communities and other collective modalities, as well as those that are developed over a considerable duration, are the ones that best affect the incorporation of learning obtained by teachers.
EVALUASI BELAJAR DARING: BAGAIMANA PERAN REGULASI DIRI TERHADAP KEPUASAN BELAJAR DARI RUMAH SELAMA PANDEMI?
Authors: Wibowo Doddy Hendro , Nainggolan Erida Yeussy
Published: June 2022

Pandemi menyebabkan mahasiswa mengalami kelas pembelajaran daring pertama kali dan kepuasan belajar daring menjadi indikator penentu keberhasilan belajar daring. Namun di lapangan, mahasiswa merasa tidak nyaman dengan metode belajar daring. Tujuan penelitian ini adalah menguji peran regulasi diri belajar daring terhadap tingkat kepuasan belajar daring mahasiswa di masa belajar dari rumah. Penelitian ini melibatkan 281 mahasiswa universitas di Salatiga berusia antara 17-23 tahun dengan metode purposive sampling. Berdasarkan hasil penelitian disimpulkan bahwa ada pengaruh regulasi diri belajar daring terhadap kepuasan belajar daring mahasiswa di masa belajar dari rumah. Mahasiswa memiliki tingkat kepuasan belajar daring pada kategori sedang (71.2%) dan tingkat regulasi diri belajar daring pada kategori sedang (69.4%).
Vertical distribution and effect of the depth on growth form and genus of hard coral on coral reef in Bunaken Island, North Sulawesi, Indonesia
Authors: Reskiwati Reskiwati , Ompi Medy , Rembet Unstain N.W.J. , Kusen Janny D. , Mantiri Rose O.S.E. , Sumilat Deiske A.
Published: June 2022

Bunaken Island generally has a 90° slope and it forms like an underwater wall. However, there are several locations in Bunaken Island that have a more gradually inclined slope. This study was aimed to identify the effect of depth and slope gradient toward vertical distribution on growth forms and genera of hard coral at three stations in Bunaken Island. The data was collected using Line Intercept Transect (LIT) method which was dragged vertically at 3-15 meters depth. The results of study showed two different types of slopes, steep and gentle slopes. Stations 1 and 2 were categorized as steep slope (90° and 55°, respectively) and station 3 was gentle slope (43°). Encrusting growth forms dominated at 90° slope, while at 55° and 43° slope was dominated by massive growth forms. Vertical distribution of the corals shows change in size and numbers of colonies along with increasing depth.
Effect of SiO2 sublayer on the retention characteristics of nanometer-sized Si3N4 memristive devices investigated by low-frequency noise spectroscopy
Authors: Kochergin Viktor S. , Yakimov Arkady V. , Klyuev Alexey V. , Filatov Dmitry O. , Gorshkov Oleg N. , Antonov Dmitry A. , Mikhaylov Alexey N. , Sunyaikin Denis V. , Shtraub Nikolay I. , Vasileiadis Nikolaos , Dimitrakis Panagiotis , Spagnolo Bernardo
Published: June 2022

The results of the experimental investigation of the relationship between the low-frequency noise spectrum of the electric current through conducting filaments in Si3N4 films with a thickness of 6 nm on n
++-Si(001) conducting substrates and retention characteristics of these filaments are reported. Two structures are investigated: Si3N4/Si, thin (about 6 nm) Si3N4 film on the n++-Si substrate; Si3N4/SiO2/Si, a similar structure with a 2 nm SiO2 sublayer between the film and the substrate. A detailed comparison of the experimentally extracted parameters, such as average current through the filament, probability density function, and spectrum, is presented with a discussion of possible physical reasons for the difference between the testing structures and their effect on retention characteristics.
Scaturire: transitivo o intransitivo?
Authors: di Valvasone Luisa
Published: June 2022

Sono giunte alla redazione alcune domande sugli usi corretti o scorretti di scaturire, probabile sintomo di incertezze riguardo al significato del verbo e alla sua transitività o intransitività.
Impacto da capacitação em primeiros socorros sobre o conhecimento de educadores e agentes escolares
Authors: Oliveira Willian Bil de , Gonçalves Susane Helen Monteiro Satiro , Muller Patrícia da Silva , Carmo Hercules de Oliveira
Published: June 2022

Objetivo: avaliar o efeito da capacitação em primeiros socorros sobre o conhecimento dos professores e agentes de uma unidade escolar. Método: pesquisa quantitativa com delineamento quase-experimental do tipo pré e pós-teste. A população foi constituída por professores e agentes escolares de uma instituição de ensino no interior do Estado de São Paulo. A coleta de dados foi entre os meses de março e abril de 2022, aplicando-se dois instrumentos: Caracterização sociodemográfica/laboral e questionário de avaliação do conhecimento sobre primeiros socorros. Para analisar os dados empregou-se estatística descritiva, teste de Shapiro Wilk e de Wilcoxon. Resultados: Predominou o gênero feminino (66,7%), média de idade de 43 anos e 66,7% eram casados. 88,9% não participaram de disciplinas em primeiros socorros na formação e 94,5% afirmaram ter presenciado situações acidentes na unidade escolar. Houve aumento no número de acertos das questões relativas a primeiros socorros e melhora em relação aos conceitos (excelente, bom, regular e ruim), com aumento na pontuação do pré-teste para o pós-teste em 3,51 pontos e com a comparação significativa (p<0,001). Conclusão: Os achados mostram que após a aplicação da capacitação em primeiros socorros com professores e os agentes escolares houve aumento de conhecimento, competências e habilidades para atuação na unidade escolar estudada.
Effectiveness of Combining Internal Sphincterotomy in Patients Undergoing Open Hemorrhoidectomy
Authors: BC Bhagavan , KA Shashank
Published: June 2022

Hemorrhoids are one of the most common presentations of the anal canal [1]. Various treatment modalities have been described over the years. However, still hemorrhoidectomy offers the best chances of permanent cure of symptomatic hemorrhoids.[1, 2] The main complication of hemorrhoidectomy is the pain in the first postoperative week which is very uncomfortable to the patient [3]. The main cause of unpleasant post-hemorrhoidectomy pain is due to the spasm of the internal sphincter that is exposed after open hemorrhoidectomy[4, 5, 6]. Internal Sphincterotomy reduces post hemorrhoidectomy pain by abolishing the hypertonicity (spasm/pressure) of the internal anal sphincter and subsequently reduces the related post hemorrhoidectomy complications[7, 8, 9] The main aim of this study was to compare the postoperative pain and other postoperative complications in two groups of patients treated with open hemorrhoidectomy and open hemorrhoidectomy with internal sphincterotomy. In this Randomised-Control-Trial from October 2018 to April 2020, Group-A underwent open-hemorrhoidectomy and Group-B underwent open-hemorrhoidectomy and internal-sphincterotomy. They were analysed for Visual-Analog-Scale (VAS) for postoperative pain at 12 hours, 24 hours, 48 hours, Day 7, Wexner’s Score for fecal incontinence, duration of postoperative hospitalisation, return to work. Mean postoperative VAS of Group-A at 12 hours, 24 hours, 48 hours, Day-7 was 7.30, 5.03, 2.93, 1.47 respectively. For Group-B, postoperative VAS at 12 hours, 24hours, 48 hours, Day-7 was 6.10, 3.83, 2.00, 1.00 respectively. Mean duration of postoperative hospitalisation in Group-A was 3.6 days and Group-B was 2.6 days. Mean Wexner’s Score for fecal incontinence in Group-A was 0.00 and Group-B was 0.20. Mean duration of return to work in Group-A was 17.43 days and Group-B was 10.23 days. Results were analysed and were found to be statistically significant. Patients of Group-B (open hemorrhoidectomy with internal sphincteroto
Treatment of Posterior Cruciate Ligament Disinsertion by Posterior Screw Fixation: A Review of 3 Cases
Authors: Dahmani Youness , Errachid Mohamed Badr , Bassir Reda Allah , Boufettal Moncef , Kharmaz Mohamed , Lamrani Moulay Omar , Berrada Mohammed Saleh
Published: June 2022

Posterior cruciate ligament (PCL) injuries have a reported incidence of between 3% and 37%, depending on the clinical setting [1]. Posterior cruciate ligament (PCL) avulsion fracture is a rare trauma pathology. Oriented by a careful clinical examination, magnetic resonance imaging (MRI) confirms the diagnosis. Surgical treatment gives good functional results in most cases. The evolution of knee ligament surgery has not made posterior cruciate ligament (PCL) surgery as reliable and reproducible as anterior cruciate ligament (ACL) surgery. The treatment of posterior cruciate ligament (PCL) injuries remains a particularly debated subject in terms of indications but also in terms of technical choices and approach. We describe in this work the reinsertion of the posterior cruciate ligament in its retro-spinal surface of the tibia by screwing in 2 sportsmen victims of high energy sports accidents and a 3rd patient victim of a fall in the stairs knee in hyperextension, the patients are carriers of an "isolated" desinsertion of the posterior cruciate ligament (PCL).
Bilateral Transfemoral Amputation in a 45 Day Old Secondary Infant to Traditional Treatment in a Developing Country
Authors: Coulibaly L. , Tambassi S.I. , Keïta I. , Coulibaly T.
Published: June 2022

Lower limb amputations are well known with various etiologies. In contrast, bilateral variability secondary to traditional treatment, especially in infants, has received little attention in the literature. The WHO estimates that 80% of rural populations living in developing countries rely on Traditional Medicine for their health needs. We report the observation of a bilateral transfemoral amputation in a 45-day-old infant initially treated by a traditherapeute for swelling of both thighs. The treatment consisted of bilateral restraint with traditional splints, which developed into ischaemic gangrene of both lower limbs during 28 days of restraint, which led to a consultation at the Gabriel Touré University Hospital in Bamako. Faced with this dreadful situation, an amputation was immediately carried out to save the life of the innocent infant. The traditional treatment, despite the damage it causes, is practised everywhere in Africa. The authors plead for information and sensitisation of the population on the danger of this practice. They recommend to the public authorities and to national and international institutions working for the well-being of children, the urgent need to put in place a regulation of these anarchic and co-pilot practices which are a great source of handicaps in our population and moreover among children.
Fahr's Syndrome- An Interesting Case Presentation
Authors: Bouktib Y. , Elhadri K. , Boutakioute B. , Idrissi M.Ouali El , Ganouni N.CherifIdrissi El
Published: June 2022

Idiopathic basal ganglia calcification (IBGC), commonly referred to as Fahr’s disease, is a rare neurological disorder characterized by the abnormal, symmetrical, and bilateral calcification of the basal ganglia and other brain regions. Patients typically present in their forties and fifties with various neurologic and/or psychiatric symptoms, including movement disorders, Parkinsonism, psychosis, and depression. The pathophysiology of this disease is not completely understood; however, several gene mutations have been identified in the pathogenesis of Fahr’s disease. These mutations display an autosomal dominant inheritance pattern. Furthermore, the regional phenotypic expression of calcifications differs greatly from patient to patient, as do their clinical presentations. Here, we describe a patient who presented with psychiatric manifestations and imaging consistent with Fahr’s disease.
Isolated Splenic Tuberculosis - A Rare Condition: A Case Report
Authors: Bouktib Y. , Adegbindin W , Benzalim Pr , Alj Pr
Published: June 2022

Tuberculosis remains one of the most prevalent and fatal infectious diseases in spite of considerable improvements in medical science. Tuberculosis is an important health problem in developing countries. There are few cases of solitary splenic tuberculosis reported in the literature internationally Here we report a case of surgically confirmed mass-forming solitary splenic tuberculosis in a 54-year-old woman who presented with abdominal discomfort for 4 months, but with no other symptoms. Laboratory data provided no specific information for diagnosis. Abdominal ultrasonography revealed a large hypoechoic lesion within the spleen. Computed tomography scan of the abdomen showed a solitary hypodense lesion.
Museums for Equality – Diversity and Inclusion How the premises of Cultural Accessibility corroborate the Social Function of Museums
Authors: Sarraf Viviane
Published: June 2022

The article “Museums for Equality – Diversity and Inclusion: How the assumptions of Cultural Accessibility corroborate the Social Function of Museums” presents and debates current concepts and data about Cultural Accessibility and the rights of people with disabilities to access heritage; introduce a brief historical analysis on the relationship between museum institutions and their public, with enphasis of people with disabilities, and points out some guidelines for the development of museum accessibility programs in order to corroborate with the Social Function of museums.

Key words: Cultural Accessibility, People with Disabilities, Inclusion
The museologist as a social worker in the construction of unprecedented futures
Authors: Brayner Vânia
Published: June 2022

In this article, I bring the discussion about the category ‹‹social worker››, with which the Marxist Paulo Freire challenges us to make a choice: either we adhere to change, in the sense of our true humanization built on political action, with a view to acting collectively. towards an autonomous and emancipatory posture, or we are in favor of permanence, comfortably silent in the face of the injustices and barbarities of our time, waiting for a pre-given future, “as a mechanical repetition of the present” (Freire, 2013). In the field of museology, I discuss this Freirean category contained in the intellectual production and action of Waldisa Rússio, to which I attribute the pioneering use of the term in Brazilian museology. And I conclude that, based on Freire and Rússio, the idea of the museologist as a social worker is fully compatible with the theoretical-methodological principles of sociomuseology.

Keywords: Sociomuseology; Social Worker; Paulo Freire
Paulo Freire, teaching museology and museums: a journey of discovery, learning and love
Authors: Célia Santos Maria
Published: June 2022

From an analysis of the research, teaching and extension actions developed in her teaching practice at the Federal University of Bahia and the Lusophone University of Humanities and Technologies of Lisbon, with Paulo Freire's work as one of the main references, the authoress selects themes that generate the Freiriano universes and museology, approaches them and records that these were important foundations for the development of her walk as a museologist-educator-educanda. Analyzes the contexts, the different concrete realities in which the authoress was immersed and was gradually building dialogical and collaborative actions, approaching the work of the Master. Problematizes the reality of museums when enter the world of museology, analyzing the limits, silences and technicality. Broadens her reflections on the museal practices enriched in the dynamics of the social process, by suggesting the redefinition of the concept of museal fact and the inclusion of new actions to the process of musealization.

Key-words: Paulo Freire; Education; Museology; Teaching; Research and Extension; Cultural Heritage; Museums
Memories of Negritude: the popular movement on the outskirts of Olinda as a Heritage of EJA
Authors: Conceição da Silva Maria
Published: June 2022

This article addresses part of the political, professional and spiritual trajectory of Yalorixa (a Candomble female priestess), Master in Education, specialist in Youth and Adult Education, Black Movement militant, Maria Conceição da Silva, with the objective, through this narrative, of registering and preserving the history of popular movements, black culture and Youth and Adult Education in Olinda, a city in the state of Pernambuco, Brazil. The life story, the basis of this article, was narrated in the virtual lecture "Memories of Blackness: the popular movement in the outskirts of Olinda as the Heritage of Youth and Adult Education", promoted and recorded on video, on July 9, 2020, by the Collective of researchers of the Masters and PhD course in Museology from the Lusófona University of Humanity and Technologies (ULHT), called Sociomuseology+Paulo Freire.

Keywords: Yalorixá; Popular movements; Black culture; Olinda, Eduacation
Problems of Searching for an Artistic Image and Stylistic Orientation Architecture of Voronezh at the Turn of the Twentieth and Twenty-First Centuries
Authors: Гилев С. А.
Published: June 2022

Постановка задачи. Анализируются стилистические направления некоторых объектов, построенных в Воронеже на рубеже двадцатого и двадцать первого веков. Результаты. Выполнен сравнительный анализ архитектурно-художественных особенностей и стилистической направленности проектных решений объектов, дана оценка их влиянию на окружающую городскую среду и формирование архитектурного облика Воронежа. Выводы. Строительство ряда объектов на рубеже этого периода и целенаправленные поиски художественного образа в архитектуре зданий существенно обогатили архитектурный облик городской среды, сделали ее более разнообразной и интересной.

Statement of the problem. The article analyzes the stylistic trends of some objects built in Voronezh at the turn of the twentieth and twenty-first centuries. Results. A comparative analysis of architectural and artistic features and stylistic orientation of design solutions of objects, their impact on the urban environment and the formation of the architectural appearance of Voronezh is carried out. Conclusions. Construction of some objects at the turn of this period and purposeful search for an artistic image in building architecture enormously enriched the cityscape and made it more appealing and diverse.
Designing an Artistic Interior: Some Issues and Development Prospects of the Industry Under Sanctions
Authors: Подольская Л. В.
Published: June 2022

Постановка задачи. Рассматривается проблема поиска новых путей развития отечественной архитектуры и дизайна интерьеров в современных условиях. Результаты. Отмечается, что уход с российского рынка западноевропейских мебельных магазинов и глянцевых журналов обнажил серьезную проблему - утрату собственного стиля, индивидуальности, творческого подхода. Отечественные дизайнеры и архитекторы в последние десятилетия привыкли работать, ориентируясь на зарубежные образцы, заимствуя идеи и решения. А в отсутствие зарубежных материалов, мебели, предметов интерьера такой подход вызвал растерянность многих специалистов. Выводы. Сложившаяся ситуация некоторой «оторванности» от западного рынка открывает новые перспективы для российских дизайнеров и архитекторов, связанные с поиском собственного стиля, художественного образа, ориентированных на отечественную культуру, историю. Необходим осознанный подход к художественному проектированию, формированию собственного стиля с ориентацией на отечественного производителя и отечественные материалы. В этом контексте особенно интересным представляется изучение архитектуры и интерьеров советского периода, которые в силу политических обстоятельств были закольцованы на внутреннее производство, причем не только строительных материалов, но художественных, монументальных работ.

Statement of the problem. The problem of searching for new ways of developing the domestic architecture in interior design in modern conditions is explored. Results. It is noted that moving away from the Russian market of Western European furniture stores and glossy magazines has brought to the surface a serious issue of losing a unique style, individuality and an artistic approach. Designers and architects in this country in the last decades have got used to working guided by foreign approaches, borrowing ideas and solutions. With no foreign materials, furniture items being available, this approach has puzzled a lot of specialists in the industry. Conclusions. The current «isolation» from the foreign market opens up new opportunities for Russian designers and architects related to searching for their own style employing domestic production and materials. Therefore it is of particular interest to investigate the architecture and interiors of the Soviet era which due to the political circumstance at the time were centred around the domestic production of not only construction materials but also artistic monumental pieces.
Pertimbangan Hakim terhadap Perceraian Akibat Nikah Dini Masyarakat Manado
Authors: Bukido Rosdalina , Setiawan Dedi , Makka Misbahul Munir
Published: June 2022

The phenomenon of divorce in early marriage often occurs in the Manado Religious Court, where there are 5 cases of divorce lawsuits at an early age. This study aims to show the factors that cause divorce in early marriage in the eyes of the judges of the Manado Religious Court. This research method is qualitative which focuses on field research. Data obtained at the Manado Religious Court in the form of reasons for divorce due to early marriage, both from the results of the decision and interviews with the judges of the Manado Religious Court. The results found are that divorce in early marriage at the Manado Religious Court is caused by several factors, namely bickering, irresponsibility, bad habits and a third person. Through the judge's consideration, that of all the factors that emerged led to quarrels, continuous quarrels and ended in divorce. So the judge judged that if you were to marry, it would be better to mature yourself as well as possible so that when problems occur in the household, they can be resolved properly without taking the divorce route.
PECULIARITIES OF USING HOMOGENEOUS ASYNDETIC COMPLEX SENTENCES IN THE LANGUAGE OF FOLKLORE
Authors: Mamutova Ulmeken Usaynovna
Published: June 2022

The importance of learning the language of folklore is shown in the study of the emergence and development of the Karakalpak literary language. One of the most important issues in the history of the Karakalpak literary language is the study of the language of epics, as well as the oral traditions of the people, along with written memoirs in determining its origin and development.
KEYWORDS: Epic, literary language, syntax, grainless speech, linguo-folkloristics.
Pemanfaatan WhatsApp sebagai Media Literasi Digital untuk Dakwah di Kalangan Mahasiswa
Authors: Salsabila Fahmi , Muslim Ibnu Fiqhan
Published: June 2022

Di era teknologi dan komunikasi yang semakin canggih, maka cara kita menyampaikan dakwah juga perlu melakukan evolusi mengikuti perkembangan tersebut. WhatsApp sebagai salah media sosial yang banyak digunakan oleh masyarakat karena memiliki kemudahan dalam mengoperasikan aplikasinya. Kemudahan serta kelengkapan WhatsApp sebagai media sosial digunakan untuk media komunikasi dan memberikan informasi ini, menjadikan WhatsApp digunakan oleh banyak forum sebagai media untuk menyambungkan komunikasi dalam forum tersebut. Dari hasil pendapat para mahasiswa yang mengikuti wawancara, dapat disimpulkan bahwa pemanfaatan WhatsApp sebagai media literasi untuk dakwah memiliki pengaruh yang cukup baik. Hal tersebut dikarenakan kegiatan literasi digital untuk Dakwah harus muncul dari kesadaran pribadi, sedangkan media yang ada diberikan melalui media sosial WhatsApp merupakan bacaan, gambar atau video yang bersifat menginformasikan, mengingatkan, serta mengajak untuk belajar tentang Islam dan lebih mendalami kajian dalam agama Islam. Terdapat pengaruh positif pemanfaatan WhatsApp dalam meningkatkan literasi Digital untuk dakwah, namun efektivitasnya belum dapat dipresentasikan besarnya. Keterbatasan penelitian ini menggunakan sample yang jumlahnya 10 mahasiswa dan penelitiannya hanya berupa observasi, wawancara serta bersumber dari beberapa kajian pustaka. Perkembangan media sosial yang diperkirakan akan terus berkembang pesat ke depannya seiring dengan terus berkembangnya teknologi komunikasi akan memiliki kontribusi yang tinggi terhadap cara berkomunikasi dan cara menyampaikan informasi, khususnya dalam dunia dakwah.
Pengaruh Motivasi Kerja, Kepuasan Kerja dan Komitmen Organisasional terhadap Organizational Citizenship Behavior pada Karyawan PT PLN (Persero) UP3 Ternate
Authors: R Ismail Nurul Husna , Nurlaila Nurlaila , M. Mustafa Ikrima
Published: June 2022

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh Motivasi Kerja, Kepuasan Kerja dan Komitmen Organisasional secara parsial maupun secara simultan terhadap Organizational Citizenship Behavior (OCB) karyawan PT. PLN (Persero) UP3 Ternate. Penelitian ini menggunakan pendekatan kuantitatif. Populasi yang digunakan dalam penelitian ini meliputi seluruh karyawan PT. PLN (Persero) UP3 Ternate sebanyak 50 orang. Teknik pengumpulan data dilakukan melalui observasi, wawancara serta pembagian kuesioner dimana pada pembagian kuesioner menggunakan teknik probability sampling dengan jenis simple random sampling. Adapun analisis data penelitian ini menggunakan bantuan SPSS versi 26 sebagai alat uji statistic. Hasil penelitian menunjukan bahwa (1) Hasil Uji Parsial memperlihatkan nilai signifikansi Motivasi Kerja terhadap Organizational Citizenship Behavior (OCB) menunjukan bahwa tidak terdapat pengaruh Motivasi Kerja terhadap Organizational Citizenship Behavior (OCB) karyawan di PT PLN (Persero) UP3 Ternate. Pada Standardized Coefficients beta (?) memperlihatkan pengaruh negatif. (2) Nilai signifikansi pengaruh Kepuasan Kerja terhadap Organizational Citizenship Behavior (OCB) memperlihatkan terdapat pengaruh Kepuasan Kerja terhadap Organizational Citizenship Behavior (OCB) karyawan di PT PLN (Persero) UP3 Ternate. Sedangkan pada Standardized Coefficients beta (?) memperlihatkan pengaruh positif. (3) Nilai signifikansi pengaruh Komitmen Organisasional terhadap Organizational Citizenship Behavior (OCB) menunjukan bahwa terdapat pengaruh Komitmen Organisasional  terhadap Organizational Citizenship Behavior (OCB) karyawan di PT PLN (Persero) UP3 Ternate. Sedangkan pada Standardized Coefficients beta (?) memperlihatkan pengaruh positif. (4) Berdasarkan hasil Uji Regresi Linear Berganda diketahui nilai signifikansi pengaruh variabel Motivasi Kerja, Kepuasan Kerja, dan Komitmen Organisasional secara simultan berpengaruh terhadap Organizational Citizenship Behavior (OCB) karyawan di PT PLN (Persero) UP3 Ternate dengan persentase pengaruh secara simultan sebesar 76,7%.
Involvement of retroelements in the autoimmune response in humans
Authors: Okay Sezer
Published: June 2022

Retroelements are mobile genomic components requiring an RNA intermediate which is reverse-transcribed into complementary DNA for transposition. Human genome contains a vast amount of retroelements including retrotransposons and endogenous retroviruses. These elements are categorized according to presence or absence of long terminal repeats, LTRs or non-LTRs, as well as autonomous and non-autonomous according to involvement of reverse transcriptase. The retroelements have been accumulated in mammalian genomes over all evolutionary times through vertical transmission, and many of them were inactivated through accumulation of mutations. However, the retroelements entered into genome within the last 200,000 years are mostly functional. Some of the active retroelements are associated with varying autoimmune diseases because anti-retroelement antibodies might cross-react with other proteins in the human body. For instance, autoimmunity and inflammation could be stimulated by increased expression of long interspersed element 1 (LINE-1 or L1) or decreased L1 degradation. Different regulation of L1 expression might be related to the genetic and sex-related variations or environmental factors. Activation of retroelements is also controlled by epigenetic silencing mechanisms such as histone modification. Elevated levels of L1 retroelements could trigger the production of type I interferon, a crucial innate defense mechanism in mammals against viruses, and systemic autoimmune response is induced. Loss-of-function in some deoxyribonucleases (DNases) such as three prime repair exonuclease 1 that degrades reverse-transcribed DNA is also related to autoimmune diseases. Additionally, human endogenous retroviruses also play a role in autoimmune diseases. Involvement of retroelements in autoimmune disorders is exemplified with three diseases, i.e. systemic lupus erythematosus, Aicardi–Goutières syndrome, and multiple sclerosis.
Initiation to Robotic Arm Control and Image Processing with CMUCAM Module
Authors: Radi O. , Simon B. , Dagorette M. Marthiens , Dondon Ph.
Published: June 2022

This aim of this paper is to share novel or different didactical experience, taking into account evolution of student’s behaviour. We describe briefly some of these major changes. The consequences on the quality and efficiency of traditional pedagogy are then pointed out. From these observations, we show that didactical adaptations must be done, in particular to improve interest, involvement, and motivation. As an example, we present here a didactical project called “initiation to robotic arm control and image processing”. Technical approach and design are detailed. Finally, we discuss the advantages of our approach and give results we obtained through this didactical process.
Magnetic Torquers Only Attitude Control of a 3U Cube Satellite
Authors: Erturk Mehmet Fatih , Hajiyev Chingiz
Published: June 2022

In this paper, attitude control of a 3U CubeSat is discussed using magnetic torquers only. As the capabilities of attitude control systems increase, the use of magnetic torques in the CubeSat is becoming more popular. Attitude control using only magnetic torquers has been researched for years and is still a current problem to study. This paper presents the use of an LQR controller for a 3U CubeSat without full gravity gradient stability of the model in a deterministic approach.