bluuebunny/crossref_metadata_2025 huggingface dataset:
O poczuciu tajemnicy i dylematach gatunkowych w obrębie kategorii konfesyjności w prozie Swietłany Aleksijewicz Czarnobylska modlitwa. Kronika przyszłości
Authors: Stępniak Anna
Published: July 2023

The article refers to Chernobyl prayer, the documentary prose of Svietlana Alexievich. The aim of the article is to draw attention to the presence of the genres of confession and prayer in the reportage. They are used by the interlocutors, who entrusted the journalist with their accounts of the traumatic experiences in connection with the Chernobyl nuclear disaster in 1986. The author focuses on showing various features of both genres (intimacy, familiarity, discretion) and describes them with the perspective of an average person who unknowingly and instinctively searches in them for answers that medicine and science cannot give. Alexievich’s reportage describes the loneliness of an individual in the face of events that most ignore in silence, while their participants remain helpless and mutilated for life.
Biologia de Marava arachidis (Yersin, 1860) (Dermaptera: Labiidae) alimentada com Brevicoryne brassicae (Linnaeus, 1758) (Hemiptera: Aphididae)
Authors: Oliveira Filho Manoel Cícero de , Silva Karla Mariana , Brito Carlos Henrique de
Published: July 2023

Estudos com espécies de Dermaptera, como Marava arachidis, atuando sobre insetos-praga contribuem na descoberta de novos agentes para o uso em programas de controle biológico. Assim, o objetivo deste estudo foi avaliar os aspectos biológicos de M. arachidis alimentada com Brevicoryne brassicae. A pesquisa foi desenvolvida sob condições controladas de temperatura (25 ± 1 ºC), umidade relativa (70 ± 10%) e fotofase (12 h). Os insetos foram obtidos de criações mantidas em laboratório. No experimento, indivíduos de M. arachidis foram individualizados e alimentados diariamente com B. brassicae. O delineamento foi o inteiramente casualizado, com cinco tratamentos (1º, 2º, 3º, 4º e 5º ínstares) e 20 repetições, avaliando a sobrevivência ninfal, o número e a duração dos ínstares, dados morfométricos e o número de indivíduos posturados, em resposta a alimentação com B. brassicae. Os dados foram submetidos à análise de variância e as médias foram comparadas pelo teste de Tukey a 5% de significância. A sobrevivência de ninfas e de adultos não foi afetada após a alimentação com B. brassicae. A duração dos ínstares variou de 9 a 15 dias, o peso médio das ninfas de 0,0017 a 0,0112 g, o tamanho corporal de 4,15 a 9,24 e o tamanho da cápsula cefálica aumentou de acordo com o avanço do estágio ninfal. O número de ninfas posturadas foi de 12,2. A alimentação da tesourinha M. arachidis com B. brassicae proporcionou a sua sobrevivência, a sua viabilidade ninfal, o desenvolvimento corporal e a sua reprodução.
Pré-tratamento termo-ácido e hidrólise enzimática de uma mistura de casca de cacau e bagaço de malte
Authors: Albuquerque Garcia Gabriel , Pereira Lôbo Frederico , Dos Santos Morais Kátia , Barbalho Dantas Bezerra Márcio , Aguiar de Oliveira Elizama
Published: July 2023

O uso dos resíduos agroindustriais (RAI) tem se destacado por sua constituição (celulose, hemicelulose, amido etc.) – que ao ser hidrolisada, libera açúcares fermentescíveis – e, devido ao fato de o Brasil possuir um forte setor agroindustrial, o país apresenta uma grande disponibilidade e variedade de RAI. Assim, tendo em vista propor a utilização de RAIs disponíveis no Sul da Bahia para obtenção de bioetanol, investigou-se uma mistura equivalente (p/p) de casca de cacau (CC) e bagaço de malte (BM). As melhores condições de processo, que resultaram em 224,37 µmol/g de açúcares redutores (glicose) por peso de resíduos, foram definidas com o auxílio da ferramenta estatística de Planejamento Experimental para o pré-tratamento [razão de sólidos totais de 5,3% (p/v), 0,5% (v/v) de HCl, 15 min de autoclavagem] e para a hidrólise [pH = 4,0, carga enzimática total de amilases comerciais por peso de sólidos totais de 40 U/g, 70 °C e 30 min]. O meio hidrolisado obtido foi então fermentado por 18 h, resultando em 4,06% (v/v) de etanol, e os resultados obtidos até o momento indicam que a mistura de CC e BM, ao invés do uso individual destes resíduos, pode ser destinada a diferentes bioprocessos. Observou-se também que o aumento da proporção de CC na mistura diminui a massa hidrolisada, devido à sua diferente composição química, o que comprova a necessidade de avaliar diferentes técnicas de pré-tratamento para diferentes proporções de RAI e assim otimizar a obtenção de açúcares fermentescíveis.
Labor Demand Responses to Changing Gas Prices
Authors: Bossler Mario , Moog Alexander , Schank Thorsten
Published: July 2023

In course of the current energy crisis, the consequences of increasing gas prices are heavily discussed. To date, however, there is no evidence of the impact of gas prices on the labor market. Using administrative employment data from 2012 to 2020, we find for manufacturing establishments a gas price elasticity of labor demand of −0.02, likely reflecting a scale effect. We also show that a rise in the gas price leads to an increase in establishment closure. A negative impact of the gas price on wages of 2 percent is consistent with rent-sharing.
Green supported silver nanoparticles over modified reduced graphene oxide: Investigation of its antioxidant and anti-ovarian cancer effects
Authors: Chen Wei , Huang Lili , Zhou Bing
Published: July 2023

A green biosynthesis of silver nanoparticles (AgNPs) decorated Mentha longifolia root extract-functionalized graphene oxide (GO) nanohybrid material has been described. Initially, the Mentha longifolia root was coated on GO’s surface. The phytochemicals of the plant acted as reducing agent for reduction of silver ions and GO to form the rGO-Mentha/Ag nanocomposite. The nanocomposite was characterized using FE-SEM, EDX, FT-IR, TEM, elemental mapping, and XRD analysis. The cells treated with rGO-Mentha/Ag nanocomposite were assessed by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay for 48 h about the cytotoxicity and anti-human ovarian cancer properties on normal (HUVEC) and human ovarian cancer cell lines, i.e., SKOV3 and A2780. The IC50 of rGO-Mentha/Ag nanocomposite were 181.2 and 196.4 µg/mL against SKOV3 and A2780cell lines, respectively. The viability of malignant human ovarian cell line reduced dose-dependently in the presence of rGO-Mentha/Ag nanocomposite. After clinical study, rGO-Mentha/Ag nanocomposite can be introduced as a novel composite in the treatment of human ovarian cancer.
Approximate Deconvolution with Correction – A High Fidelity Model for Magnetohydrodynamic Flows at High Reynolds and Magnetic Reynolds Numbers
Authors: Batugedara Yasasya , Labovsky Alexander E.
Published: July 2023

We propose a model for magnetohydrodynamic flows at high Reynolds and magnetic Reynolds numbers.
The system is written in the Elsässer variables so that the decoupling method of [C. Trenchea, Unconditional stability of a partitioned IMEX method for magnetohydrodynamic flows, Appl. Math. Lett.
27 (2014), 97–100] can be used.
This decoupling method is only first-order accurate, so the proposed model aims at improving the temporal accuracy (from first to second order), as well as reducing the modeling error of the existing turbulence model.
This is done in the framework of the recently developed LES-C turbulence models [A. E. Labovsky, Approximate deconvolution with correction: A member of a new class of models for high Reynolds number flows, SIAM J. Numer. Anal.
58 (2020), 5, 3068–3090].
We show the model to be unconditionally stable and numerically verify its superiority over its most natural competitor.
Some results of homogeneous expansions for a class of biholomorphic mappings defined on a Reinhardt domain in ℂ
n
Authors: Sima Xiaoying , Tu Zhenhan , Xiong Liangpeng
Published: July 2023

Let

S

γ
,
A
,
B

∗

(

D

)

{S}_{\gamma ,A,B}^{\ast }\left({\mathbb{D}})

be the usual class of

g

g

-starlike functions of complex order

γ

\gamma

in the unit disk

D
=

{

ζ
∈
C
:
∣
ζ
∣
<
1

}

{\mathbb{D}}=\left\{\zeta \in {\mathbb{C}}:| \zeta | \lt 1\right\}

, where

g

(

ζ

)

=

(

1
+
A
ζ

)

∕

(

1
+
B
ζ

)

g\left(\zeta )=\left(1+A\zeta )/\left(1+B\zeta )

, with

γ
∈
C
\

{

0

}

,
−
1
≤
A
<
B
≤
1
,
ζ
∈
D

\gamma \left\in {\mathbb{C}}\backslash \left\{0\right\}\right,-1\le A\lt B\le 1,\zeta \in {\mathbb{D}}

. First, we obtain the bounds of all the coefficients of homogeneous expansions for the functions

f
∈

S

γ
,
A
,
B

∗

(

D

)

f\in {S}_{\gamma ,A,B}^{\ast }\left({\mathbb{D}})

when

ζ
=
0

\zeta =0

is a zero of order

k
+
1

k+1

of

f

(

ζ

)

−
ζ

f\left(\zeta )-\zeta

. Second, we generalize this result to several complex variables by considering the corresponding biholomorphic mappings defined in a bounded complete Reinhardt domain. These main theorems unify and extend many known results.
Kierkegaard and the Figure of the Philistine: a Negative Way of Highlighting Existence
Authors: Bord Jérôme
Published: July 2023

In this paper, I propose a study of the figure of the philistine (Spidsborgeren) as the embodiment of spiritlessness in Kierkegaard. Indeed, although the pseudonyms aim at representing all the possibilities of existence, declining at the same time the diverse degrees of inwardness, the philistine appears throughout the whole work as the very paradigm of the lack of inwardness. While this figure stands as a kind of antipseudonym, I thus argue that it plays a decisive role in Kierkegaard, because it enables him to constitute and to structure, in a negative way, his philosophy of existence.
“My Dear Reader—but to Whom Am I Speaking?” Kierkegaard Read with the Rhetorical Theory of Narrative
Authors: Hämäläinen Ville
Published: July 2023

This article introduces a rhetorical theory of narrative in reading Kierkegaard, comparing Kierkegaard’s praxis to Phelan’s definition of “somebody telling somebody else that something happened on some occasion and for some purpose(s).” Use of pseudonyms problematizes “the somebody” telling and makes apparent the differing purposes of author and narrator. In the early authorship, the purpose is usually a life-view. The “something happened” may seem irrelevant in Kierkegaard, but it evokes questions of lived experience and life-view. The “occasion” for telling is textually mediated, and thus draws a novel connection to literary history. Finally, I examine Kierkegaard’s real and authorial readers.
Der Begriff Ernst. Zur Kritik ironischer Selbstverhältnisse bei Hegel und Kierkegaard
Authors: Böhm Sebastian
Published: July 2023

The article aims at giving an account of and comparing Hegel’s and Kierkegaard’s critique of contemporary culture by focussing on the category of seriousness. Both thinkers diagnose a general tendency of downplaying, in fact, suppressing or even abolishing consciousness of sin and a concomitant disappearance of seriousness in what they consider „the modern age of reflection.“ First, the concept of seriousness is spelled out within their respective philosophies of religion, and this in relation to the reality of sin as a misguided and distorted relationship to God. Second, the idea of seriousness is analysed with special reference to the different forms and stages of spirit (in Hegel), on the one hand, and „dialectical seriousness“ (in Kierkegaard) on the other hand. Third, major similarities and differences in both accounts are pointed out, in order, finally, to draw some, partly critical, consequences regarding current and future Kierkegaard research.
The Young Kierkegaard as a Student of Liunge’s Kjøbenhavnsposten
Authors: Stewart Jon
Published: July 2023

Kierkegaard is well known for his quick wit and sharp polemics against his opponents. One of his favorite targets was the poet, dramatist, and philosopher, Johan Ludvig Heiberg (1791 – 1860). Perhaps the best-known element of his critique was Heiberg’s outspoken Hegelian campaign. Before Kierkegaard’s famous criticisms of Heiberg, he learned the craft of literary polemics by reading the lively discussions in the Danish journals of the time. In this article it is argued that the role of the journal Kjøbenhavnsposten for Kierkegaard has never been appreciated. This journal was edited by Andreas Peter Liunge (1798 – 1879), who was a great adversary of Heiberg and his Kjøbenhavns flyvende Post. The article shows that the often satirical use of Hegel by Kjøbenhavnsposten to criticize Heiberg anticipates Kierkegaard’s strategy of critique with regard to Heiberg and other figures in the Danish Hegelian movement.
Kierkegaard: Existenzphilosoph nur im ‚Nebenberuf‘? Überlegungen im Anschluss an Jürgen Habermas
Authors: Victor Oliver
Published: July 2023

This paper discusses Habermas’s characterization of Kierkegaard as a religious author in his main profession and as an existential philosopher on the side. I would like to argue that Kierkegaard is primarily an existential philosopher, also in his function as a religious author. At first, I would like to interpret his religious authorship as a form of indirect communication, and after that I discuss indirect communication as a method of existentialism. In this way, the article aims to demonstrate that Kierkegaard becomes the precursor of existential philosophy not least by his religious authorship as a theory and practice of indirect communication.
Multimodal discursive strategies for building social, intellectual, and symbolic capital for women empowerment
Authors: Maier Carmen Daniela
Published: July 2023

The purpose of this article is to show how to identify and clarify the roles of distinctive discourses in empowering and advocacy communication meant to create bridging and bonding social capital through building new intellectual and symbolic capital. More precisely, the purpose is to explain the roles of multimodal discursive strategies employed when issues of gender equity and empowerment are communicated in corporate context, viz. in employee magazines, by world-acclaimed women professional athletes and corporate employees. For accomplishing this purpose, a series of multimodal interviews appearing in the Puma’s online employee magazines, Puma Catch Up, are systematically examined. Overall, the study suggests that especially legitimations used by successful professional women are key discursive resources for empowering women across various kinds of borders and for creating a corporate symbolic capital. By outlining how legitimations constitute empowering and advocacy discursive resources, this research work contributes with a multimodal perspective to the field of social change communication.
SMOC2 plays a role in heart failure via regulating TGF-β1/Smad3 pathway-mediated autophagy
Authors: Ren Yu , Wu Yun , He Wenshuai , Tian Yingjie , Zhao Xingsheng
Published: July 2023

Heart failure (HF) is a major global cause of morbidity and mortality. This study aimed to elucidate the role of secreted protein acidic and rich in cysteine-related modular calcium-binding protein 2 (SMOC2) in HF development and its underlying mechanism. Using a rat HF model, SMOC2 expression was examined and then knocked down via transfection to assess its impact on cardiac function and damage. The study also evaluated the effects of SMOC2 knockdown on autophagy-related molecules and the transforming growth factor beta 1 (TGF-β1)/SMAD family member 3 (Smad3) signaling pathway. Intraperitoneal injection of the TGF-β agonist (SRI-011381) into the HF rat model was performed to explore the SMOC2-TGF-β1/Smad3 pathway relationship. SMOC2 expression was elevated in HF rats, while its downregulation improved cardiac function and damage. SMOC2 knockdown reversed alterations in the LC3-II/I ratio, Beclin-1, and p62 levels in HF rats. Through transmission electron microscope, we observed that SMOC2 knockdown restored autophagosome levels. Furthermore, SMOC2 downregulation inhibited the TGF-β1/Smad3 signaling pathway, which was counteracted by SRI-011381. In conclusion, SMOC2 knockdown inhibits HF development by modulating TGF-β1/Smad3 signaling-mediated autophagy, suggesting its potential as a therapeutic target for HF.
Applications of DNA tetrahedron nanostructure in cancer diagnosis and anticancer drugs delivery
Authors: Long Qipeng , Tian Xinchen , Wang Haochen , Zhang Ni , Han Tao , Li Zhe , Jiang Shulong
Published: July 2023

DNA nanostructures constructed under the guidance of DNA nanotechnology have developed rapidly for the last two decades, standing at the forefront in the biomedical field. Among them, DNA tetrahedron nanostructure (DTN) has emerged as one of the most representative DNA nanostructures. DTN was easily formed by one-step annealing of four single-stranded DNA. Due to its unique advantages such as simple and stable structural composition, high synthesis efficiency, uniform nanometer size, high programmability, and good biocompatibility, DTN has been widely used in biological detection, biological imaging, drug delivery, and other fields, and shows a great potential. Especially in the detection of cancer-related biomarkers and the delivery of anticancer drugs, nano-platforms based on DTN has achieved great success. In this review, we focus on the applications of DTN in cancer diagnosis and therapy, as well as the challenges and prospects.
Graphene nanofibers: A modern approach towards tailored gypsum composites
Authors: Martinez Gordon Alejandro , Prieto Barrio María Isabel , Cobo Escamilla Alfonso
Published: July 2023

Energy poverty is a global challenge that demands sustainable and affordable solutions. This study investigates the use of commercial graphene nanofibers (GNFs) as a reinforcing agent in gypsum composites for energy-efficient building retrofitting. The GNFs were manually dispersed in the gypsum matrix, and the composites were fabricated by casting and curing. The thermomechanical properties were systematically studied using various characterization techniques, including scanning electron microscopy, X-ray diffraction, and thermal analysis. The results show that the addition of 1% GNFs reduces the thermal conductivity of the composites by more than 40% and improves their flexural and compressive strength by up to 23 and 42%, respectively, compared to neat gypsum. The enhancements are attributed to the effective phonon scattering of the GNFs and their ability to act as crystal seeding sites, resulting in a denser and more homogeneous structure. The dynamic thermal analysis further demonstrates that the GNF-reinforced composites could reduce heating and cooling requirements by 14 and 11%, respectively, indicating their potential for energy-efficient building retrofitting. However, the cost effectiveness and safety issues of the GNF-reinforced composites should be carefully considered before their large-scale implementation. Achieving uniform dispersion of nanoparticles in high concentrations is also a significant challenge that will be addressed in future studies.
Ethics for Philosophers: An Introduction
Authors: Curren Randall
Published: July 2023

This paper addresses the responsibilities of philosophers. It distinguishes philosophers by profession, philosophers as a type of person playing a social role by doing philosophy, and philosophers without any professional or social role as a philosopher. It criticizes and rejects the internal goods view of philosophers’ responsibilities, according to which a philosopher’s only responsibility as a philosopher is to do ‘good’ philosophy. It examines the responsibilities of philosophy professors and the role of philosophy teaching in liberal education, criticizing the implications of the internal goods view for university missions and commenting on related deficiencies of the Code of Conduct of the American Philosophical Association. The central conclusions are that philosophers should accept responsibilities to do philosophy in the public interest and to adopt a cross-disciplinary and collaborative stance toward their role in educating students in the forms of understanding and judgment that will best equip them for life and citizenship.
Teaching Philosophy from Scratch: Designing Dynamic Pedagogy for Adult ‘Firsts’
Authors: Zack Naomi
Published: July 2023

I describe dynamic teaching to adult, mainly immigrant students, who are new to philosophy and often are college “firsts.” Adult students have family, financial, and work obligations, whereas standard students are leisured outside of class and approach philosophy as consumers. I teach from assigned texts, dismissing as a conceit of philosophers that philosophical questions arise from real life experience. My students are intensely focused on their grades, frugal with their expenditure of academic effort, and prone to submit all of their coursework at the end of the semester. A syllabus requiring weekly assignments with citations curtails that. For immigrant students, who value their college degree as entry to the American dream, the hard work usually ascribed to them is, here, academic work. Learning to do philosophy in this way can result in enduring meta-skills of time management, focused reading, thinking, and group participation that carry over to other subjects and real life.
The Evolution of the Thought of Richard Peters: Neglected Aspects
Authors: Winch Christopher , Gingell John
Published: July 2023

Peters is best known for ‘Ethics and Education’, (1966) an attempt, using analytical methods, to provide a universal canonical account of the nature of education. This corresponded closely with the prevailing conception of liberal education of the time. Despite the acclaim with which this work was received, Peters became increasingly dissatisfied with his early views of education and in a series of papers written between 1973 and 1982, he retreated slowly from the view that one could construct a universal canonical account of education and even from the view that this could be possible for liberal education. As his views changed, his philosophical methods developed as well, moving from the Moorean essentialist analysis of 1966, through a more Strawsonian connective analysis in the mid 1970s to a position based on W.B. Gallie's account of essentially contested concepts in the early 1980s. Parallel to and connected with this changing philosophical methodology came a distinction between an overarching concept of education and particular conceptions of education related to different societies and their values.
Conjunctival congestion: a novel clinical sign in older children with Tetralogy of Fallot
Authors:   Department of Pediatrics, All India Institute of Medical Sciences, Patna, Bihar, India, Prasad Arun , Kumar Pradeep ,   Department of Pediatrics, All India Institute of Medical Sciences, Patna, Bihar, India, Raj Amit ,   Department of Ophthalmology, All India Institute of Medical Sciences, Patna, Bihar, India, Nayak Yankappa ,   Department of Pediatrics, All India Institute of Medical Sciences, Patna, Bihar, India
Published: July 2023

Tetralogy of Fallot is the most common cyanotic heart disease in children. While doing echocardiographic examination of children with Tetralogy of Fallot, we observed that many older children with this condition had congestion in their bulbar conjunctiva, easily recognizable even from some distance. This observation led us to design and perform a research study in order to find out the presence of conjunctival congestion in children with Tetralogy of Fallot. 85% of children in the ≥ 5-years of age group had conjunctival congestion without any ocular symptoms. This novel clinical finding can act as an adjunct clinical sign for recognizing Tetralogy of Fallot in older children.
Reed Sternberg-Like Cells in Non-Hodgkin Lymphoma: A Diagnostic Challenge
Authors:   Department of Pathology, King George’s Medical University, Lucknow, India, Yadav Geeta , Singh Anurag ,   Department of Pathology, King George’s Medical University, Lucknow, India, Jain Mili ,   Department of Pathology, King George’s Medical University, Lucknow, India, Kushwaha Rashmi ,   Department of Pathology, King George’s Medical University, Lucknow, India, Verma Shailendra Prasad ,   Department of Clinical Hematology, King George’s Medical University, Lucknow, India
Published: July 2023

Reed-Sternberg cells are distinguishing features of classical Hodgkin lymphoma. However, they are seen infrequently, in both B and T cells NonHodgkin lymphomas with a comparable morphology and immunophenotype. These cells are known as Reed-Sternberg-like cells. The characteristic background milieu of classical Hodgkin lymphoma is typically not present in Non-Hodgkin lymphomas, and Reed-Sternberg-like cells are typically present as dispersed cells or in tiny clusters. They are positive for CD30, show variable expression of B cell lineage markers and are negative for CD45/LCA in Non-Hodgkin lymphomas. Reed-Sternberg-like cells have phenotypes that are remarkably similar to those of conventional Reed-Sternberg cells. In this interesting case report, we discuss a case of disseminated B-cell Non-Hodgkin lymphoma with Reed-Sternberg-like cells that presented as a diagnostic challenge. It is essential to distinguish between classical Hodgkin lymphoma and NonHodgkin lymphomas due to distinct therapy protocols and prognosis. The presence of large CD30 positive Reed-Sternberg like cells may mimic Hodgkin’s Lymphoma. However, monomorphic background population with CD20 positivity should always raise the suspicious of B-cell Non-Hodgkin lymphoma. Immunohistochemical detection of a panel of targets should always be applied to correctly diagnose these rare cases of B-cell Non-Hodgkin lymphoma with Reed-Sternberg like cells.
Short-term energy drink consumption influences plasma glucose, apolipoprotein B, body mass index and pulse rate among students
Authors:   Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka, Nigeria, Iheanacho Munachimso Mariasonia , Analike Rosemary Adamma ,   Department of Chemical Pathology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria, Meludu Samuel Chukwuemeka ,   Department of Chemical Pathology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria,   Department of Human Biochemistry, Faculty of Basic Medical Sciences, Nnamdi Azikiwe University, Awka, Nigeria, Ogbodo Emmanuel Chukwuemeka ,   Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka, Nigeria, Onah Christian Ejike ,   Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka, Nigeria
Published: July 2023

OBJECTIVE: Energy drinks are becoming more popular every year, particularly among young adults such as college students, despite evidence that they have harmful health effects. The effect of energy drink consumption on plasma glucose, serum apolipoproteins, and triglyceride levels in students was investigated. METHODS: In order to test this, we chose two representative types of energy drinks in Nigeria, namely fearless and predator. These energy drinks are brand names of non-alcoholic beverages aimed to provide energy. 30 students, apparently healthy male human subjects aged 18 to 30 years who gave informed consent to the research work were randomly selected and divided into two groups: Group A (fearless energy drink consumers, n=15) and Group B (predator energy drink consumers, n=15). RESULTS: The results demonstrated significant reductions in pulse rate (86.00±41.32 vs. 78.87±27.72; p=0.03) and BMI (21.41±1.93 vs. 21.7±12.02; p=0.00) as compared to baseline values after one month of “fearless energy drink” consumption. Plasma glucose levels were significantly higher (97.53±10.62 vs. 88.80±11.33; p=0.01) and Apo B levels were significantly lower (21.41±1.93 vs. 21.71±2.02; p=0.00) following two weeks of fearless energy drink consumption than in baseline. In addition, BMI and Apo B levels were significantly lower after two weeks of predator energy drink consumption, but plasma glucose levels were significantly higher after two weeks and one month of predator energy drink consumption, respectively (p<0.05). SBP, DBP, TG and Apo A levels did not differ significantly in both fearless and predator energy drink consumers at baseline and after the study period respectively (p>0.05). CONCLUSION: This study has shown that the consumption of energy drinks causes significant alterations in BMI, pulse rate, plasma glucose and apolipoprotein B levels which may have important clinical consequences for energy drink consumers.
Análise comparativa das louças encontradas em áreas de ocorrência arqueológica na região metropolitana de Curitiba, Paraná
Authors: De Araújo Barbosa Jardel Stenio , Oliveira dos Santos Marcos Vinicius , Marino de Araújo Paula Rocha , Lino Jaisson Teixeira
Published: July 2023

O presente artigo tem por objetivo apresentar um estudo comparativo das louças encontradas em áreas de ocorrência arqueológica na região metropolitana de Curitiba. As ocorrências foram identificadas durante trabalhos de Acompanhamento Arqueológico na área de instalação de dois condomínios residenciais, o Condomínio Madison na cidade de Campo Largo e o Condomínio Benvenue no município de Almirante Tamandaré. Esse trabalho busca demonstrar o potencial informativo dos artefatos coletados durante os trabalhos de arqueologia preventiva, bem como visa contribuir com os estudos acerca da louça de fabricação nacional tendo em vista que essa região foi uma das pioneiras na produção industrial desses objetos.
 
Abstract:
This article aims to present a comparative study about refined earthenware found in archaeological occurrence areas in the metropolitan area of Curitiba. The fragments were identified during Archaeological Monitoring studies in the construction area of two residential condominiums: Condomínio Madison, in the city of Campo Largo, and Condomínio Benvenue, in the city of Almirante Tamandaré. The purpose of this research is to show the informative potential of the artifacts collected during the preventive archaeology services, as well as contributing to studies related to brazilian earthenware production, considering this region was one of the pioneers in the industrial production of these objects.
Territorialidade negra no espaço transnacional entre Brasil e Guiana Francesa: O caso da comunidade quilombola Kulumbu do Patuazinho (1990 a 2021)
Authors: Lima Jelly Juliane Souza de , Gambim Júnior Avelino , Carneiro Kathelin Thayssa Mendonça , Silva Edineth Alves da , Santos Batista Claudemir dos
Published: July 2023

As fronteiras entre o Brasil e a Guiana Francesa, especificamente no município de Oiapoque, no estado do Amapá, constituem-se em espaços de diversidade sociocultural. No entanto, ainda são escassos os estudos sobre formações de comunidades negras ou quilombolas. Neste artigo, procuramos compreender o processo de formação da comunidade quilombola Kulumbu do Patuazinho e suas relações com o território ocupado. A pesquisa de campo foi pautada no uso de metodologias como história oral, observações etnográficas e caminhamentos pela comunidade. Nesse caso, os resultados da pesquisa permitiram compreender que a migração de um núcleo familiar negro vindo do estado do Maranhão na década de 1990 não pode ser explicada somente pela busca de melhores condições de vida, mas deve estar pautada nas relações com os guias espirituais de matriz africanaque impulsionaram a chegada a esse lugar, e as misturas com outros grupos que vivem na região e suas cosmologias.
Resenha do livro Entre “Bricolagens” e Narrativas: possibilidades para um “fazer” historiográfico
Authors: Silva Eliane Araujo
Published: July 2023

Esta resenha traz uma leitura do livro Entre "Bricolagens" e Narrativas: possibilidades de um fazer historiográfico, organizado pela Historiadora e Arqueóloga Ana Lúcia do Nascimento Oliveira. Dividido em três eixos temáticos: Patrimônio Cultural, Educação Patrimonial e Ensino de História; Patrimônio cultural, Cultura popular e Memória; e Patrimônio Cultural e História Colonial, traz na apresentação da obra a intenção da proposta inspirada no termo “bricolage”, que traduzido do francês indica, trabalho manual e/ou artesanal e que também é forma de fazer com materiais diferentes – o que dá o tom da diversidade, imaginação e criatividade – propostas nas narrativas presentes. Abstract:This review brings a reading of the book Between "Bricolagens" and Narrativas: possibilities of a historiographical doing, organized by Historian and Archaeologist Ana Lúcia do Nascimento Oliveira. Divided into three thematic axes: Cultural Heritage, Heritage Education and History Teaching; Cultural Heritage, Popular Culture and Memory; and Cultural Heritage and Colonial History, brings in the presentation of the work the intention of the proposal inspired by the term “bricolage”, which translated from French means manual and/or artisanal work and which is also a way of making with different materials – which gives the tone of diversity, imagination and creativity – proposals in the present narratives.
Advances in Left Bundle Branch Pacing: Definition, Evaluation, and Applications
Authors: Zeng Jiaxin , Xue Siyuan , Zou Fengwei , Qiu Yuanhao , Zou Jiangang
Published: July 2023

Left bundle branch pacing (LBBP) emerged as a new physiological pacing strategy during the past several years. Recent observational studies have demonstrated the advantages of LBBP, including a high success rate, stable pacing parameters, and excellent clinical benefits. Widespread adoption of LBBP will depend on improvements in device/lead technology and further verification of its efficacy in large randomized clinical trials. In this review, we summarize recent advancements in LBBP, including the definition and evaluation of left bundle branch capture, LBBP applications, and future directions in this growing field.
Plant YTHDF proteins are direct effectors of antiviral immunity against an N6‐methyladenosine‐containing RNA virus
Authors: Martínez‐Pérez Mireya , Aparicio Frederic , Arribas‐Hernández Laura , Tankmar Mathias Due , Rennie Sarah , von Bülow Sören , Lindorff‐Larsen Kresten , Brodersen Peter , Pallas Vicente
Published: July 2023

In virus–host interactions, nucleic acid‐directed first lines of defense that allow viral clearance without compromising growth are of paramount importance. Plants use the RNA interference pathway as a basal antiviral immune system, but additional RNA‐based mechanisms of defense also exist. The infectivity of a plant positive‐strand RNA virus, alfalfa mosaic virus (AMV), relies on the demethylation of viral RNA by the recruitment of the cellular N6‐methyladenosine (m6A) demethylase ALKBH9B, but how demethylation of viral RNA promotes AMV infection remains unknown. Here, we show that inactivation of the Arabidopsis cytoplasmic YT521‐B homology domain (YTH)‐containing m6A‐binding proteins ECT2, ECT3, and ECT5 is sufficient to restore AMV infectivity in partially resistant alkbh9b mutants. We further show that the antiviral function of ECT2 is distinct from its previously demonstrated function in the promotion of primordial cell proliferation: an ect2 mutant carrying a small deletion in its intrinsically disordered region is partially compromised for antiviral defense but not for developmental functions. These results indicate that the m6A‐YTHDF axis constitutes a novel branch of basal antiviral immunity in plants.
PRINCIPALS’ DIGITAL TRANSFORMATIONAL LEADERSHIP, TEACHERS’ ORGANISATIONAL COMMITMENT AND JOB SATISFACTION DURING COVID-19 IN LAGOS STATE EDUCATION DISTRICT V, NIGERIA
Authors: Nurudeen Olalekan Orunbon  , Ganiyu Abiona Ibikunle  , Adewale Abiodun Badmus
Published: July 2023

Several leadership specialists have studied the impact of principals' transformational leadership on school administration. Yet, studies and research on the digital transformational leadership of school administrators have received little attention from academics. As the COVID-19 pandemic has caused countries all over the globe to switch to online teaching and learning paradigms, it is imperative to close the gap. The principal had to adopt a new position as a digital leader, working online with teachers and students, according to the changing circumstances. The goal of this study is to ascertain how school principals' leadership in digital transformation during COVID-19 in senior secondary schools in Education District V, Lagos State, Nigeria, and teachers' organisational commitment and work satisfaction are related. Information from 300 educators in the School District is used to support the research. The results show that principals' digital transformational leadership and teachers' organisational commitment have a strong significant and positive relationship. They also show a strong significant and positive relationship between principals' digital transformational leadership and teachers' job satisfaction. The findings of this study reveal that principal digital transformational leadership behaviour  play a critical role in fighting the COVID-19 pandemic by encouraging teachers to be creative, innovative, and undertaking active actions for the achievement of organisational commitment and job satisfaction, as well as to ensure the school organisation’s sustainability. Based on these conclusions, the study suggested that the Lagos State government, through the Education District V, should support professional development initiatives like conferences, workshops, seminars, and training for secondary school teachers to keep their knowledge current, particularly their knowledge of digital technology.
An ovarian phenotype of alpha 7 nicotinic receptor knockout mice
Authors: Seßenhausen Pia , Caban Karolina M , Kreitmair Nicole , Peitzsch Mirko , Stöckl Jan B , Meinsohn Marie C , Pépin David , Popper Bastian , Fröhlich Thomas , Mayerhofer Artur
Published: July 2023

In brief

Nicotinic acetylcholine receptor alpha 7 (nAChRa7), encoded by Chrna7, is expressed by various murine ovarian cells. Morphological and molecular investigations, including a proteomic study of adult Chrna7 knockout (KO) mouse ovaries, reveal the roles of these receptors in the local regulation of the ovary.

Nicotinic acetylcholine receptor alpha 7 (nAChRa7), encoded by Chrna7, is involved in cellular functions ranging from synaptic transmission in neurons to regulation of inflammation, cell growth and metabolism to cell death in other cells. Our qPCR results and other studies indicated that nAChRa7 is expressed in the adult mouse ovary, while in situ hybridization and single-cell sequencing data suggested this expression may be shared by several ovarian cells, including fibroblast-like and steroidogenic stroma cells, macrophages and oocytes of small follicles. To explore a possible involvement of nAChRa7 in ovarian functions, we evaluated ovarian morphology of Chrna7-null mutant adult mice (KO) and wildtype mice (WT; 3 months, metestrus) by performing immunohistochemistry, qPCR studies, measurements of serum progesterone and proteomic analyses. The evaluation of serial sections indicated fewer primordial follicles but similar numbers of primary, secondary and tertiary follicles, as well as corpora lutea in KO and WT mice. Atresia was unchanged. Serum progesterone and mRNA levels of proliferation and most apoptosis markers were not changed, yet two typical macrophage markers were elevated. Furthermore, the proteomes of KO ovaries were significantly altered with 96 proteins increased and 32 decreased in abundance in KOs compared to WTs. Among the elevated proteins were markers for stroma cells. Hence, the lack of nAChRa7 causes changes in small follicle counts and alterations of the ovarian stroma cells. The ovarian phenotype of Chrna7 mutant mice links this channel protein to the local regulation of ovarian cells, including stroma cells.
Promotions and Team Building for Marketing Campaigns
Authors: Sodoma Ruslana , Kovalchuk Oleg , Sadura Oksana , Popadynets Nazariy
Published: July 2023

The article analyzes in detail the main aspects of promotional marketing in team building. Team building is very important for marketing campaigns as it allows for the efficient completion of tasks and the achievement of set goals. The main purpose of the article is based on the evaluation of the effectiveness of marketing communications using the Yule model and the creation of a framework for the business modeling of the brand, since having a ready-made business model structure, one can describe the cost structure, which will reflect the key actions and all resources for investment in brand development. The article summarizes the main advantages and disadvantages of promotions and highlights the main consequences of the war for Ukrainian brands. The main reason for team building is that marketing campaigns usually require work with different specialists such as marketers, designers, copywriters, analysts, etc. Therefore, project teams secure necessary communication and coordination between project participants to avoid misunderstandings and ensure the successful implementation of the project. Moreover, project teams can secure efficient management of resources such as time, budget, and other resources. This is especially important for marketing campaigns since they often have limited resources and shorter deadlines. Each team member contributes and performs specific tasks to achieve the campaign goal. Team building is an essential element in the successful implementation of marketing campaigns. It allows for efficient communication and coordination among project participants, resource management, and the achievement of successful results. Effective promotions can provide a company with a competitive advantage. This article discusses the main types of promotions, such as advertising, discounts, gifts, contests, loyalty, etc. An important aspect is choosing the right type of promotion depending on the target audience and the company's marketing goals. The criteria for team building, including the abilities and skills of the participants, leadership, communication, and collaboration, are also considered. The concept of business management implies that the company's management should constantly work to improve business processes, optimize the use of resources, and efficiently utilize personnel. In addition, business management includes the development and implementation of the company's development strategy, as well as control over its financial results.
Tax Policy Formation in the Context of European Integration Processes
Authors: Zhuk Olha , Hoi Nataliia
Published: July 2023

The article deals with the study of the process of tax policy formation in the context of European integration. The relationship and influence of European integration processes on the formation of tax policy is determined. The analysis of the impact of European integration on the country's tax policy and the main aspects that have an impact on the formation of tax policy were investigated. The article emphasizes the role of European standards and recommendations in construction an effective tax policy.Prospective directions of tax policy formation in connection with European integration processes are considered. The main problems of tax policy formation and aspects of the obligations defined by the Association Agreement between Ukraine and the European Union are described, including: harmonization of tax legislation, efforts against tax evasion and tax avoidance, ensuring transparency and efficiency of the tax system. In addition, the article mentions the positive impact of European integration on the development of the business environment and the creation of conditions for investment attraction. Measures to be implemented to ensure a fair and efficient tax policy, as well as to reduce tax barriers to attract investment and prevent tax evasion are also defined. The main changes in the norms of tax legislation, which must be made in accordance with the requirements of the European Union, are considered. It is noted that the development and adoption of certain norms of tax legislation are insufficient, since it is also necessary to form the administrative potential of the tax administration. The challenges facing the country in adapting to European standards in the field of taxation are considered and described.According to the draft Plan for the Recovery of Ukraine, the main goals of tax policy formation are reflected, taking into account the requirements of Ukraine's integration into the European Union. The main areas of tax reform have been determined, including: formation of a favorable tax policy for economic growth; adaptation of the norms of tax legislation in accordance with the Association Agreement to the requirements of the European Union; improvement of tax administration to increase investment activity.
Desempeño mecánico del concreto convencional reemplazando agregado grueso con polietileno de tereftalato
Authors: Sanabria Rojas Madelein Natalia , Gil Peláez Jhon Jairo , Duarte Barón Katherin
Published: July 2023

En muchos países los residuos plásticos son una parte contaminante del medio ambiente, por tal razón es necesario buscar alternativas en las que se pueda reutilizar de forma masiva, para disminuirlos significativamente. En este proyecto de investigación se realizó una búsqueda de trabajos asociados a la temática, se analizaron las técnicas utilizadas y los resultados obtenidos, de manera que se recolectó el material necesario y mediante ensayos de laboratorio se fabricaron cilindros de concreto con distintas sustituciones de los agregados gruesos por residuos plásticos (PET); con el fin  de comparar las resistencias y costos de los moldes de concreto celular y con residuos plásticos; y así determinar la viabilidad de los agregados de plásticos en el concreto celular. En cada una de las proporciones de residuos plásticos utilizados se observó una disminución del peso y menor costo, sin embargo, ninguno logró superar la resistencia mínima, comparada con un cilindro convencional, al ser sometido a las pruebas de compresión, siendo el tamaño de los residuos la mayor problemática para obtener buenos resultados. Para utilizar residuos de plástico en la mezcla de concreto tradicional, es recomendable, reducir el tamaño de la partícula para mejorar la cohesión de los materiales, es decir Polipropileno de Tereftalato triturado, que sirva para el diseño de sistemas estructurales y que obtengan una mayor resistencia, con esto la contaminación debida a residuos plásticos disminuiría significativamente.
Optimization of parameters for vacuum heat modification of Cupressus funebris wood
Authors: Wang Jialei , Lyu Jianhua , Li Xianwei , Jiang Yongze , Chen Ming
Published: July 2023

A full factorial experiment was conducted to analyze the main and interaction effects on the physical and mechanical properties of Cupressus funebris Endl. wood subjected to vacuum heat modification. The response variables evaluated were mass loss rate (ML, %), moisture resistance (MR, %), and modulus of rupture in bending (MOR, MPa). The results reveal significant variations in the effects of modification time, holding temperature, and vacuum pressure as independent factors, along with varying degrees of interaction effects among them. Simplifying the analysis model, a regression equation was derived to describe the relationship between the response variable (mass loss rate) and the factors: The model achieved an R-squared value of 96.0% and an R-squared (predicted) value of 73.7%, indicating good overall predictive performance. Optimal process parameters for mid-temperature vacuum heat modification of cypress were determined based on the mass loss rate and modulus of rupture (MOR), resulting in a modification temperature of 120 °C, holding time of 5 h, and a pressure intensity of 0.1. The reliability of the full factorial experiment was further confirmed through orthogonal testing.