bluuebunny/crossref_metadata_2025 huggingface dataset:
American and Austrian Ruins in Korngold’s Symphony in F-sharp
Authors: Wlodarski Amy Lynn
Published: May 2020

This chapter shows that Erich Korngold's compositional process and materials reflected a particular traumatic mode of modernism—the ruin. Here, recognizable fragments from the past recall an uncomfortable or contested history of decay and destruction. Ruinous art forms betrayed the “temporal and spatial doubts that modernity always harbored about itself.” While some manifest as a material fascination with destruction and demise, others constitute an aesthetic that enables the audience to think about the historicity of our condition and even experience hope. Korngold noted that his preference lay with the latter. But Korngold's Symphony in F-sharp, Op. 40 (1947–52), in its quiet references to earlier repertories whose musical lives were deeply entangled in the modern historical moment, signaled its own disturbing relevance to the ruins of the time—whether the crumbling facades of Korngold's beloved Vienna or his experience in America as an exile in a state of fracture and suspension.
La participación del Estado en la plusvalía como una deuda ciudadana
Authors: Garzón Zabala Vanessa
Published: May 2020

La participación del Estado en la plusvalía del suelo derivada de la acción urbanística es un mecanismo constitucionalmente legítimo en la recaudación de ingresos del patrimonio público, para promover el desarrollo urbanístico de los territorios. Por tanto, la línea argumentativa parte de justificar que la captación de los dineros provenientes de este instrumento es un asunto de equidad ciudadana, apoyándose en el principio de la función social en la propiedad y el enriquecimiento sin causa de particulares propietarios y poseedores. Posteriormente, se hace una breve contextualización de la recuperación de plusvalías a nivel internacional, para exponer dos casos exitosos en Brasil y Uruguay. Y finalmente, se determina la viabilidad de promover acciones judiciales efectivas para el cobro de la participación de la plusvalía.
Sociedad civil y pobreza, Estado racional y justica social. El problema de la pobreza en la Filosofía del derecho de Hegel
Authors: Rojas Hernández Mario
Published: May 2020

Aun cuando Hegel constata graves problemas y conflictos del Estado moderno y los analiza y critica de manera sutil, no los resuelve de forma que se pueda considerar adecuada, satisfactoria y completa. Uno de estos grandes problemas es el de la pobreza y la miseria generadas por el sistema económico del Estado moderno. El texto se ocupa de este problema en la Filosofía del Derecho de Hegel. Primero, presenta elementos irrenunciables de la teoría hegeliana. En seguida se expone y analizan elementos centrales de la sociedad civil estrechamente vinculados con la pobreza. Por último, se llevan a cabo reflexiones críticas de la propuesta de Hegel, principalmente en el sentido de que es necesaria otra forma de sociedad civil, en específico, del “sistema de las necesidades”, es decir, el sistema económico de producción, distribución y consumo de la riqueza generada en y por la comunidad política (el Estado, en sentido amplio), para poder aspirar a solucionar el problema de la pobreza y la injusticia social.
La tradición católica, su influencia en la conformación del rol de la mujer en la familia tradicional colombiana y su relación con la violencia de pareja al interior de ésta
Authors: Mazo Gómez Wilson De Jesús
Published: May 2020

De acuerdo con el Instituto Nacional de Medicina Legal y Ciencias Forenses, en su informe Forensis 2017. Datos para la vida, los hechos de discriminación y violencia de pareja contra las mujeres en Colombia se han incrementado en los últimos años; esta situación podría catalogarse como producto de una sociedad que ha sido moldeada a partir del esquema machista y patriarcal que caracteriza a las sociedades que han estado influenciadas por tradiciones como la religión católica, que parecen justificar, en algunos de los relatos de sus textos sagrados, la condición de dominación que ejerce el hombre sobre la mujer. El Estado colombiano, que en sus inicios normativos se vio influenciado por esta tradición, ha buscado, a partir de la Constitución de 1991, y a través de su posterior normatividad, no solo la reivindicación de la mujer, sino la sanción a los agresores; sin embargo, estas medidas no han sido eficientes ya que no se ha podido garantizar un verdadero ambiente de seguridad y respeto por los derechos fundamentales de las mujeres. Por lo tanto, se hace necesario intervenir la configuración de la cultura colombiana, en aras de modificar las bases culturales sobre las cuales se construyó el imaginario social que perpetúa la estructura de dominación y discriminación contra la mujer.
España y Venezuela como impulsores de la academia contable colombiana
Authors: Macías Hugo Arlés
Published: May 2020

El objetivo de este trabajo es destacar el papel que han jugado, recientemente, dos programas de doctorado y un pequeño grupo de académicos de España y Venezuela, en la cualificación de la academia contable colombiana. Profesores de diferentes ciudades se han vinculado como estudiantes a estos doctorados y han empezado a tejer redes que les permiten participar en discusiones más exigentes, tanto a nivel de congresos, como de publicaciones. La masa crítica que se está formando permitirá que, en la tercera década del siglo, la academia colombiana participe activamente en las discusiones extrarregionales de la frontera del conocimiento en contabilidad.
La investigación formativa en programas de contaduría: el caso de la Universidad de Antioquia
Authors: Castaño Rios Carlos Eduardo
Published: May 2020

La necesidad imperante de formar contadores públicos integrales lleva a la constante pregunta sobre qué componentes deben considerarse a la hora de plantear una innovación curricular. Dentro de tal discusión se ha venido consolidando la idea de que la investigaciónes clave para que este profesional se pueda desempeñar de forma adecuada en su devenir como parte de la sociedad; por eso, el objetivo de este trabajo fue presentar el caso de la Universidad de Antioquia frente a los procesos de investigación formativa, como una evidencia adicional de la importancia que toma este asunto en los programas de contaduría pública a lo largo y ancho del país. Se concluye sobre la relevancia de seguir incluyendo la investigación formativa desde planos curriculares y extracurriculares, con el fin de que los futuros profesionales contables cuenten con más y mejores herramientas  para desempeñarse en las organizaciones donde aplicarán su conocimiento.
Evaluation of relationships between results of electrocardiography and echocardiography in 341 chimpanzees (Pan troglodytes)
Authors: Drane Aimee L. , Atencia Rebeca , Cooper Stephen-Mark , Feltrer Yedra , Calvi Thalita , Strike Tai , Palmer Christopher , Simcox Sarah , Rodriguez Pablo , Sanchez Carlos , van Bolhuis Hester , Peck Bruce , Eng Jaclyn , Moittie Sophie , Unwin Steve , Howatson Glyn , Oxborough David , Stembridge Mike R. , Shave Rob E.
Published: May 2020

OBJECTIVE

To examine potential relationships between ECG characteristics and echocardiographic measures of cardiac structure in chimpanzees (Pan troglodytes).

ANIMALS

341 chimpanzees (175 males and 166 females) from 5 sanctuaries and 2 zoological collections.

PROCEDURES

Chimpanzees were anesthetized for routine health examinations between May 2011 and July 2017 as part of the International Primate Heart Project and, during the same anesthetic events, underwent 12-lead ECG and transthoracic echocardiographic assessments. Relationships between results for ECG and those for echocardiographic measures of atrial areas, left ventricular internal diameter in diastole (LVIDd), and mean left ventricular wall thicknesses (MLVWT) were assessed with correlational analysis, then multiple linear regression analyses were used to create hierarchical models to predict cardiac structure from ECG findings.

RESULTS

Findings indicated correlations (r = −0.231 to 0.310) between results for ECG variables and echocardiographic measures. The duration and amplitude of P waves in lead II had the strongest correlations with atrial areas. The Sokolow-Lyon criteria, QRS-complex duration, and R-wave amplitude in leads V6 and II had the strongest correlations with MLVWT, whereas the Sokolow-Lyon criteria, QRS-complex duration, and S-wave amplitude in leads V2 and V1 had the strongest correlations with LVIDd. However, the ECG predictive models that were generated only accounted for 17%, 7%, 11%, and 8% of the variance in the right atrial end-systolic area, left atrial end-systolic area, MLVWT, and LVIDd, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE

Results indicated that relationships existed between ECG findings and cardiac morphology in the chimpanzees of the present study; however, further research is required to examine whether the predictive models generated can be modified to improve their clinical utility.
Evaluation of various carbon dioxide laser settings on the time and number of laser beam passes required to make a full-thickness skin incision and amount of laser-induced tissue artifact
Authors: Agulian Lori M. , Mann F. A. , Middleton John R. , Kim Dae Y.
Published: May 2020

OBJECTIVE

To evaluate the time and number of laser beam passes required to make full-thickness skin incisions and extent of laser-induced tissue artifacts following use of a CO2 laser at various settings.

SAMPLE

24 skin specimens from six 5-month-old porcine carcasses.

PROCEDURES

4 full-thickness skin specimens were harvested from the flank regions of each carcass within 30 minutes after euthanasia and randomly assigned to 4 treatment groups. Three 5-cm-long incisions were made in each specimen with a CO2 laser (beam diameter, 0.4 mm) set to deliver a continuous wave of energy alone (groups 1 and 2) or in superpulse mode (groups 3 and 4) at 10 (groups 1 and 3) or 20 (groups 2 and 4) W of power. The time and number of passes required to achieve a full-thickness incision were recorded, and extent of laser-induced tissue artifact (as determined by histologic evaluation) was compared among the 4 groups.

RESULTS

Mean time required to make a full-thickness skin incision for groups 2 and 4 (power, 20 W) was significantly less than that for groups 1 and 3 (power, 10 W). Mean number of passes was lowest for group 2 (continuous wave at 20 W). Extent of laser-induced tissue artifact was greatest for group 4 (superpulse mode at 20 W).

CONCLUSIONS AND CLINICAL RELEVANCE

Results provided preliminary information regarding use of CO2 lasers to make skin incisions in veterinary patients. In vivo studies are necessary to evaluate the effect of various CO2 laser settings on tissue healing and patient outcome.
Detection of Class Regularity with Support Vector Machine methods
Authors: Rosiana Dewi Ni Wayan Emmy , Aris Gunadi I Gede , Indrawan Gede
Published: May 2020

One of the most factor that affects the achievement and learning motivation of students is a conducive classroom environment. It can be seen from the student's regularity in the class. Teachers can determine whether the class is adequate or not by monitoring the class condition through video. The research tries to apply the extraction of imagery and sound features by using the Centroid extraction method and the MFCC along with classifying the regular or irregular classrooms with the SVM methods which are taken by video installed in a classroom. The video will be split into image data and sound data. The process of image data starts with reading the input, then it goes to the stages of preprocessing, segmentation with K-Means, morphology, and the most important part is to get information before it is classified by the SVM method to get its class regularity. The sound frequency will be extracted by the MFCC method and then it is classified by the SVM method to get the class noise. The results of this research get an accuracy value of 78% in the linear kernel and 70% in the polynomial kernel. This research uses 50 test data consisting of 25 regular data and 25 irregular data taken directly through video recording. These results prove that the SVM method has given good classification results for regular and irregular classes.
Customer Segmentation Based on RFM Model Using K-Means, K-Medoids, and DBSCAN Methods
Authors: Sembiring Brahmana Rahma Wati , Mohammed Fahd Agodzo , Chairuang Kankamol
Published: May 2020

A problem that appears in marketing activities is how to identify potential customers. Marketing activities could identify their best customer through customer segmentation by applying the concept of Data Mining and Customer Relationship Management (CRM). This paper presents the Data Mining process by combining the RFM model with K-Means, K-Medoids, and DBSCAN algorithms. This paper analyzes 334,641 transaction data and converts them to 1661 Recency, Frequency, and Monetary (RFM) data lines to identify potential customers. The K-Means, K-Medoids, and DBSCAN algorithms are very sensitive for initializing the cluster center because it is done randomly. Clustering is done by using two to six clusters. The trial process in the K-Means and K-Medoids Method is done using random centroid values ??and at DBSCAN is done using random Epsilon and Min Points, so that a cluster group is obtained that produces potential customers. Cluster validation completes using the Davies-Bouldin Index and Silhouette Index methods. The result showed that K-Means had the best level of validity than K-Medoids and DBSCAN, where the Davies-Bouldin Index yield was 0,33009058, and the Silhouette Index yield was 0,912671056. The best number of clusters produced using the Davies Bouldin Index and Silhouette Index are 2 clusters, where each K-Means, K-Medoids, and DBSCAN algorithms provide the Dormant and Golden customer classes.
EXTRAPULMONARY TUBERCULOSIS PATIENT'S PROFILE IN RSUD CIANJUR 2017 – 2019
Authors: Hariyani Rizqi Primasane , Ferdiana Fita , Hadipoetro Ferial
Published: May 2020

Background: Tuberculosis is one of the 10 causes of death in the world1. Indonesia represents the third country for tuberculosis incidence. Based on the WHO data, the number of extra-pulmonary tuberculosis (EPT) in 2017 is around 896,000 cases, that was 14% of 6.4 million tuberculosis patients2. The incidence of EPT in Indonesia, in 2012, was 17,420 cases from total of 331,424 cases3. So far there was no profile data about EPT in RSUD Cianjur even number of EPT who has been diagnosed by histopathological examination was done. Objective of this study was to determine EPT patient’s profile in RSUD Cianjur 2017 – 2018. Methods: Design of study was cross sectional, 183 samples obtained from the anatomic pathology laboratory data and the medical record for the period January 2017 - May 2019. Results: The results of the study show that the number of EPT patients at RSUD Cianjur in 2017, 2018 and 2019 is as many as 60, 71, and 52 patients. There were 10 patients <15 years of age, 148 patients between 15-50 years of age, and 25 patients >50 years of age. There were 84 male patients and 99 female patients. According to the location, 63 cases occurred in lymph nodes, 67 in the digestive system, 20 in the musculoskeletal system, 25 in the reproductive system, 6 in the thorax, 1 in the thyroid and 1 in the bone marrow. Conclusion: The proportion of patients with EPT in RSUD Cianjur in 2017 – 2019 was 6% of all tuberculosis patients. The percentage of the patients <15 years of age was 5.5%, between 15-50 years of age was 80.87%, and >50 years of age was 13.66%. Of these patients 46% were male and 54% were female. The infected location in the digestive system was 36.61%, lymph nodes were 34.43%, reproductive system was 13.66%, musculoskeletal system was 10.93%, thorax was 3.28%, thyroid was 0.55% and bone marrow was 0.55%.
CLINICAL CHARACTERISTIC OF ADULT PATIENTS WITH DENGUE HEMORRHAGIC FEVER AT PROF. DR. SULIANTI SAROSO SUNTER INFECTIOUS HOSPITAL 2018
Authors: Rasyidah Ghina , Anandani Adinta
Published: May 2020

Background: Dengue is a viral disease transmitted by mosquito to humans and becomes a problem for the health of Indonesian people. Dengue Hemorrhagic Fever occurs due to several epidemiological factors. The purpose of this study is to determine the clinical characteristics of adult patients with Dengue Hemorrhagic Fever at Prof. dr. Sulianti Saroso Sunter Infectious Hospital 2018. Method: This Study was an observational descriptive study by taking medical record samples in 49 adult patients Dengue Hemorrhagic Fever in 2018. Results: From the 49 cases of Dengue Haemorrhagic Fever, the highest fender category was male (65,3%), occurred in the 18-25 year age category (38,8%), and the average patient worked as a Private Employee (55,1%). Most patients were hospitalized for the less than 7 days (83,7%). Clinical manifestations were fever (95,9%), nausea (85,7%) and headache (71,4%). Physical examination found was fever (100%) and hepatomegaly (12,2%). Laboratory tests showed normal hematocrit values (71,4%), thrombocytopenia values (87,8%), normal leukocyte values (49%), positive IgG serology tests (83,7%), IgM serology tests (71,4%), Positive IgM and IgG Serology test (69,3%), and NS1 Serology test (2%). Management provided is the administration of intravenous infus fluid drops (100%), PPI (87,8%), H2 Antagonist (4,1%), and Antipiretik (83,7%). The outcome patient is recovered and no complications were found. Conclusion: Dengue Hemorrhagic fever occurs in the age range of 18-25 years with dominant clinical characteristic of fever and thrombocytopenia. And, the most given treatment is Intravena Fluid therapy.
Profil Prostate Spesific Antigen (PSA) pada Penyakit Prostat di Rumah Sakit Umum Daerah Cengkareng Jakarta Barat
Authors: Wulansari Nungki Septi , Marindawati Mieke
Published: May 2020

Latar belakang: kanker prostat adalah keganasan tersering dan penyebab kematian pria di negara Barat. Di Indonesia kanker prostat berada di urutan ke-3 kanker terbanyak pada laki-laki tahun 2014. Tujuan: tujuan dari penelitian ini adalah untuk mengetahui profil kadar PSA pada pasien yang terkena penyakit prostat di RSUD Cengkareng Jakarta Barat periode Januari 2016 – Agustus 2019. Metode: desain penelitian ini menggunakan desain cross sectional jenis penelitian deskriptif mengumpulkan data sekunder pasien penyakit prostat, prostatitis, Benign Hyperplasia Prostat (BPH), kanker prostat, BPH dengan prostatitis. Hasil: hasil penelitian di RSUD Cengkareng Jakarta Barat periode Januari 2016 – Agustus 2019 didapatkan pasien dengan penyakit prostat sebanyak 190 pasien. Pasien yang menderita kelainan prostat dengan PSA diatas normal (>4 ng/ml) sebanyak 139 (73%) pasien. Sedangkan didapatkan pula pasien dengan dengan penyakit prostat yang mempunyai PSA normal (≤4 ng/mL) yaitu sebanyak 51 (27%) pasien. Kesimpulan: kelainan prostat dapat terjadi pada pasien yang mempunyai nilai PSA normal (≤4 ng/mL) dan lebih dari normal (>4 ng/ml), dengan usia terjadinya kelainan prostat tersebut adalah 50 – 93 tahun.
Analisis Strategi Pemasaran pada PT. Prambanan Kencana
Authors: Willianto Willianto
Published: May 2020

PT. Prambanan Kencana is an importer and distribution company which is founded in 1953 dan they offer quality food and beverages product. This research aims to analyze marketing strategy being used in PT. Prambanan Kencana in accordance to the internal and external factor and to seek for alternative marketing strategy in PT. Prambanan Kencana by utilizing Matriks IFE, Matriks EFE, Matriks IE, and Matriks SWOT. Method used is qualitative descriptive. The result of the research depict that PT. Prambanan Kencana has its own strength, weakness, opportunity and Threats and there are strategies to handle it. PT. Prambanan Kencana also is on the V grid in Matriks IE in which the best strategy is the hold and maintain strategy.
Rice Breeding Strategies in the Philippines
Authors: Palanog Alvin D. , Mondejar Cielo Luz C. , Bello Gerald E. , Calayugan Mark Ian C , Palanog May Osano , Caguiat Xavier Greg I. , Ferrer Marilyn C. , Sta. Ines Leo T.
Published: May 2020

Rice is a major staple in the Philippines. The major goal of the rice sector in the country is to increase its productivity to meet the ever growing demand for rice. Breeding is one of the potential solutions to achieve rice self-sufficiency in the country. Rice variety development is led by research institutions such as PhilRice, IRRI, UPLB, and private companies and each adapts various breeding strategies. Rice variety normally takes 10-12 years of a journey from breeding to release and more than 300 varieties have been developed and released that were suited for various rice ecosystems. Sufficient varieties were available for production and this led to continuous in rice production for the past decade. However, yield increment has plateaued. To meet the increasing demand for rice, achieve self-sufficiency, and particularly, break the yield barrier (plateau) and achieve a leap in yield potential, breeding institutions particularly PhilRice should embrace new advances and technologies in rice breeding. The introduction of the concept of transforming breeding into a “factory line” type encouraging rapid generation advance, earlier multi-location trials, and increasing selection pressure, and employing genomic selection (GS) in handling a large quantity of materials/populations can improve breeding efficiency and outputs significantly.
Ingestão dietética de alimentos ricos em FODMAPs em portadores da síndrome do intestino irritável
Authors: Teles Karyna Batista de França , Sousa Shérlyda Memória de , Landim Liejy Agnes dos Santos Raposo
Published: May 2020

Elucidar a influência da dieta rica em FODMAPs nos sintomas de pacientes com Síndrome do Intestino Irritável. Trata-se de um estudo de caso múltiplos, realizado com pacientes que possuíam síndrome do intestino irritável, conduzido em seis indivíduos do sexo feminino. Foram analisados parâmetros de avaliação clínica e dietética, incluindo recordatório 24 horas e questionário de frequência alimentar adjunto de dados antropométricos para resultar no estado nutricional das participantes. Além disso, foi questionado os principais sintomas e causas da exacerbação da sintomatologia.  Os dados foram quantificados em gráficos e tabelas do Microsoft Excel 2016, para análise descritiva. Em relação ao estado nutricional, as pacientes apresentaram resultados diversos, não havendo prevalência. Na análise alimentar foi possível avaliar que a maioria das pacientes não estava com a ingesta calórica, glicídica, protéica e lipídica adequada, de acordo com os parâmetros comparados. Observou-se também a presença de alimentos ricos em FODMAPs que foram excluídos ou reduzidos da dieta habitual, devido a contribuição na exacerbação dos sintomas.
Angiodisplasia intestinal em paciente com doença renal crônica: relato de caso
Authors: Magalhães Rafaelly Taketomi de , Marinho Ana Wanda Guerra Barreto , Santos Samanta Samara Bicharra dos , Cavalcante Júnior José Lopes , Nascimento Larissa Lima do , Oliveira Kátia Batista de , Dias Maykon da Silveira , Queiroz Daniel Monteiro , Figueiredo Ana Beatriz da Cruz Lopo de
Published: May 2020

Objetivo: Relatar e discutir sobre a Angiodisplasia Intestinal em paciente com Doença Renal Crônica (DRC) em um hospital de atendimento terciário. Detalhamento do caso: Paciente do sexo masculino de 67 anos, diabético, hipertenso e com diagnóstico de Doença Renal Crônica dialítica há 3 anos, evoluindo com sangramento gastrointestinal há 2 anos e meio, epistaxe e perda ponderal. Foi submetido a exame de cápsula endoscópica que evidenciou múltiplas angiectasias ao longo do intestino delgado. Realizado inicialmente terapêutica farmacológica com Talidomida, Octeotidra e Desmopressina e posteriormente tratamento através de Enteroscopia com duplo balão e terapia hemostática com coagulação por plasma de argônio. Considerações finais: A angiodisplasia intestinal é uma das principais causas de hemorragia gastrointestinal nos pacientes com DRC. Sua causa exata permanece desconhecida. O diagnóstico pode ser realizado através de técnicas endoscópicas e o tratamento pode tornar-se necessário em pacientes sintomáticos, através de terapia farmacológica e coagulação com plasma de argônio.
O prontuário do paciente e o dever legal e ético de registro dos profissionais da saúde: uma revisão literária
Authors: Gomes Luis Eduardo Miani , Gomes Juliana Teixeira , Negreiros Leandro Minatel Vidal de , Leal Raquel Franco
Published: May 2020

Objective: Descrever sobre a importancia dos registros no prontuário do paciente, tendo em vista a considerável relevância do dever legal e ético dos profissionais da saúde, além de destacar a importância deste documento. Revisão Bibliográfica: Em decorrência do valor legal e ético existente no prontuário do paciente, o emprego da correta forma de preenchimento deve ser um dos preceitos legais empregados na formação profissional. O prontuário do paciente é um documento individualizado e sigiloso, amparado pelos preceitos éticos e legais, e os registros ali contidos são extremamente relevantes ao paciente e aos profissionais envolvidos nessa assistência. Desse modo, o prontuário expressa a centralização das informações, da progressão do paciente e assim deve-se empregar a real importância das informações registradas, recebendo atenção dos profissionais, transgredindo o simples registro. Considerações finais: Os profissionais devem entender a seriedade no preenchimento do prontuário do paciente, inserindo na formação básica dos mesmos elementos subsidiadores ao correto preenchimento deste documento, e ao final torná-lo adequado e em conformidade aos preceitos éticos e legais de seu preenchimento, guarda e descarte.
Percepção do impacto emocional da equipe de enfermagem diante da pandemia de COVID-19: relato de experiência
Authors: Portugal Jéssica Karoline Alves , Reis Marcelo Henrique da Silva , Barão Évelyn Janaína da Silva , Souza Tanny Thaylle Gomes de , Guimarães Ramanda Sena , Almeida Lucas da Silva de , Pereira Rhuana Maria de Oliveira , Freire Nathalie Marinho , Germano Sibele Naiara Ferreira , Garrido Marlucia da Silva
Published: May 2020

Objetivo: Relatar a percepção da equipe de enfermagem de um hospital em um município no interior do estado do Amazonas, diante da pandemia de coronavírus, expondo os principais medos e anseios frente as incertezas do novo cenário mundial e os desafios vindouros. Relato de experiência: Este relato é baseado na vivencia da equipe de enfermagem diante da pandemia do coronavírus, demonstrando seus medos e anseios e como os atuais acontecimentos no Brasil e no mundo podem afetar significativamente as condições psicológicas dos profissionais de saúde, uma vez que possuem maior risco de contaminação devido o contato direto com pacientes infectados. Desta forma, observou-se que as equipes de enfermagem têm atuado com constate pressão psicológica, podendo causar ansiedade e até mesmo depressão. Considerações finais: Os profissionais sofrem as mesmas pressões psicológicas, principalmente pelo medo diante da incerteza das condições futuras, tendo em vista a proporção da pandemia. Portanto, é preciso que os profissionais de saúde sejam atendidos em suas inquietações e desamparos, visto que a regressão da pandemia depende disso.
Öğrenci Bakış Açısıyla Probleme Dayalı Öğrenim
Authors: AKDOGAN Hayriye Dilek , VELİPAŞAOĞLU Serpil , MUSAL Berna
Published: May 2020

Giriş: Probleme Dayalı Öğrenim (PDÖ), merkezinde öğrencinin olduğu bir aktif eğitim yöntemidir. PDÖ’nün öğrencilerin kendi kendine öğrenme becerilerini ve öğrenme motivasyonlarını arttırması, problem çözme becerisi kazandırması gibi önemli kazanımları vardır. Bu çalışmada PDÖ eğitim modeli uygulanan bir fakülte olan Dokuz Eylül Üniversitesi Tıp Fakültesinde öğrencilerin PDÖ süreçleri işleyişi ve kazanımlarına ilişkin algılarının değerlendirilmesi amaçlanmıştır. Bu değerlendirmeleri yapabilmek ve verilere ulaşabilmek için, bağımsız değişkenler olarak yaş, dönem ve cinsiyet; bağımlı değişkenler olarak PDÖ oturumlarındaki performanslara ilişkin algılar, PDÖ süreçlerini etkileyen etmenlerin önem derecesinin değerlendirilmesi, PDÖ süreçlerini etkileyen etmenlerin fakültedeki uygulama düzeylerine ilişkin değerlendirmeler, PDÖ’nün öğrencilere sağladığı kazanımlara ilişkin değerlendirmeler kullanılmıştır. Çalışma hipotezi öğrencilerin PDÖ kazanımları ve performans algılarının Dönem 1’e göre Dönem 3 lehine yüksek olduğu ve cinsiyetler arasında anlamlı fark olmadığı temeline dayandırılmıştır. Araştırma kesitsel ve analitik tiptedir.Gereç ve Yöntem: 2015-2016 akademik yılı sonunda Dönem 1 ve 3 programını tamamlayan öğrencilere dört ölçek ve açık uçlu sorulardan oluşan bir anket formu uygulanmıştır. Araştırmada elde edilen veriler, SPSS 15.0 istatistik programı kullanılarak analiz edilmiştir. Bulgular: PDÖ oturumlarındaki performansları açısından kendilerini genel olarak olumlu değerlendirdikleri saptanmıştır. Bir parametrede kadın öğrencilerin puanının erkek öğrencilere göre daha yüksek olduğu görülmüştür. Dönemlere göre PDÖ oturumlarındaki performanslarına ilişkin puanları karşılaştırıldığında; Dönem 3 öğrencilerinin Dönem 1 öğrencilerine göre ‘sözel iletişimde başarı’ ve ‘grup dinamiklerini destekleyecek şekilde davranma’ açılarından performanslarını daha olumlu algıladıkları saptanmıştır.PDÖ’nün kazanımları konusunda tüm parametrelerde öğrencilerin orta değer üzerinde puanlar verdikleri belirlenmiştir.Sonuç: Öğrencilerin genel olarak PDÖ kazanımları ve performanslarını olumlu değerlendirdikleri anlaşılmıştır. Göreli olarak düşük puan verilen öğelerin nicel ve nitel yöntemlerle daha ayrıntılı olarak değerlendirilmesinin uygun olacağı düşünülmektedir.
Yapılandırılmış Bir Eğitim Modülünün, Tıp Fakültesi Öğrencilerinin Toplumsal Cinsiyet ve Flört Şiddetine Yönelik Algı ve Tutumlarına Etkisi
Authors: OZAN Sema , MİMAN Özlem , GÜVERCİN Cemal H , DEMİROĞLU UYANIKER Zehra
Published: May 2020

Amaç: Tıp öğrencilerinde uygulanan yapılandırılmış bir eğitimin toplumsal cinsiyet (TC) algısına ve flört şiddetine (FŞ) yönelik tutumlara etkisinin araştırılmasıdır. Gereç ve Yöntem: Tanımlayıcı ve metodolojik bir çalışma olan araştırmada tek grup ön-test/son-test modeli kullanılmıştır. Test olarak “Toplumsal Cinsiyet Algısı Ölçeği” ve “Flört Şiddetine Yönelik Tutum Ölçekleri” uygulanmıştır. Çalışmanın metodolojik boyutunda TC ve FŞ konularında öğrencilere farkındalık kazandırmayı, bakış açılarında esneklik, tutum ve davranışlarında olumlu yönde değişim geliştirmeyi amaçlayan bir eğitim programı uygulanmıştır. TC algısı ile kadının flört ilişkisinde uyguladığı psikolojik şiddete (K-FUPŞ) yönelik tutumların eğitim öncesi/sonrasında ve cinsiyete göre değişip değişmediği araştırılmıştır. TC algısı ve K-FUPŞ’e yönelik tutum arasındaki ilişki de incelenmiştir. Bulgular: Çalışmaya, 24 tıp fakültesi birinci sınıf öğrencisi katıldı (9 erkek; 15 kadın). Öğrencilerin TC’ye ve K-FUPŞ’ye yönelik algılarında eğitim sonrasında anlamlı değişiklik saptanmıştır. Kadınların TC’ye ve K-FUPŞ’ye yönelik algılarında eğitim sonrasında olumlu yönde değişiklik saptanırken, erkeklerin sadece TC’ye yönelik algılarında olumlu yönde değişiklik saptanmıştır. Erkek ve kadın öğrencilerin TC’ye yönelik algıları arasında eğitim öncesi ve sonrasında fark saptanmıştır. K-FUPŞ’ye yönelik tutum açısından cinsiyetler arasında sadece eğitim sonrasında fark bulunmuştur. TC algısı ile K-FUPŞ’ye yönelik tutum arasında, eğitim öncesi ve sonrasında ilişki saptanmıştır.Sonuç: Uygulanan eğitim programı, TC algısını eşitlikçi yönde, K-FUPŞ’yi de onaylamama yönünde olumlu etkilemiştir. Her iki açıdan eğitim sonrasında kadınların yaklaşımı erkeklere göre daha olumlu yönde değişmiştir. Erkeklerin, K-FUPŞ’yi onaylamama yönünde değişim göstermemeleri, konunun daha ayrıntılı araştırılması gerektiğini düşündürmüştür.Eğitim etkinliği genel olarak olumlu yönde değişim sağlamış olsa da içinde yaşanılan sosyokültürel ortamın cinsiyet normları üzerindeki belirleyici etkisi sürmekte, eşitsizlikler bilinçli ya da bilinçsiz olarak yeniden üretilebilmektedir. İstanbul Sözleşmesi ve onun doğrultusunda ortaya koyulan politikalarda belirtildiği ve Mezuniyet Öncesi Tıp Eğitimi Ulusal Çekirdek Eğitim Programı-2014’de de yer aldığı üzere TC, sağlık ve şiddet ile ilgili konulara üniversite ve tıp eğitiminde yer verilmesi önemli kazanımlar olup korunması ve daha da geliştirilmesi gerekli adımlardır.
Determination of Hopelessness Levels of Final Year Students of The Faculty of Medicine
Authors: ÖZTÜRK KAYGUSUZ Türkkan , ERENSOY Ahmet
Published: May 2020

Background: Hopelessness, which includes both the characteristics of depression and anxiety, is thought to be triggered by environmental stress. In case of hopelessness, emotional disorders, despair and inability to solve problems arise. This study was conducted to determine the level of hopelessness of the final year students in medical school and to determine whether there is a difference in the levels of hopelessness according to gender and age variables.Methods: A total of 124 medical faculty last year students, 60 of them (48.4%) male, were included in this study. Using the Beck's Hopelessness Scale Score, the hopelessness levels of the students and the three major aspects of hopelessness, i.e. feelings and expectations about the future, loss of motivation and hopes about the future were evaluated.Results: The mean Beck's Hopelessness Scale Score of the students was 6.29 . 30.6% of the students had no hopelessness, 48.4% had mild hopelessness, 13.7% had moderate hopelessness and 7.3% had severe hopelessness. No statistically significant difference was found between gender and age groups. For the students who preferred medical school to serve humanity, the mean Beck's Hopelessness Scale Score were significantly lower than those who did not prefer for this purpose; Beck's Hopelessness Scale Score means were found to be significantly higher for those who preferred to earn more money. While the majority of the students (89%) did not have any professional future concerns, it was found that the Beck's Hopelessness Scale Score mean was significantly higher in students who were concerned about not being able to earn enough in the future.Conclusion: It was found that the students' feelings and expectations about the future were not negative, the loss of motivation was not significant and the hopes about the future were quite high.
Mikrobiyoloji Uygulamalarının Klinik Eğitimde Kalıcılığının Sağlanması Amacı İle Yapılan Sınavların Öğrenci Gözü İle Değerlendirilmesi: Bir TEÖK Çalışması
Authors: GÜROL Yeşim , IŞIK Oğuz Can , ALTINTAŞ Levent , ŞAHİNER Melike
Published: May 2020

Giriş: Günümüz tıp eğitiminde öğrencilerin klinik öncesi olarak da adlandırılan ilk üç yılda uygulanan eğitim programının çıktılarına ulaşma düzeyleri ve bilgilerinin kalıcılığı, klinik uygulama yıllarına temel oluşturmasına ek olarak eğitimde yatay ve dikey entegrasyonun sağlanması açısından da önem taşımaktadır. Öğrencilerden alınan nitelikli geribildirimler ile değişen öğrenci profillerinin öğrenme beklenti ve yönelimlerinin öğrenilmesinin ve bunların karşılanmasını sağlayacak yöntemlerin eğitimde kullanılmasının gerekliliği ortaya konmaktadır.Klinik öncesinde verilen tıbbi mikrobiyoloji bilgisi öğrencilerin klinikte her an hatırlamaya ihtiyaç duyduğu mikroorganizmaların çeşitleri, özellikleri ve laboratuvar tanı yöntemlerini içermektedir. Klinik eğitimde, karşılaşılan vakalarda bu bilgiler hatırlanabilmeli ve doğru olarak kullanılabilmelidir. Bilginin kalıcılığını sağlamak amacı ile eğitim programlarının güncellenmesi; farklı öğretme, ölçme ve değerlendirme metotlarının kullanılması gündeme gelmektedir.Amaç: Bu makaledeki amaç, Acıbadem Üniversitesi Tıp Fakültesi (ACUTF) 2. Sınıf Mikrobiyoloji ders kurulundaki ölçme-değerlendirme süreçlerinde değişikliğe giderken öğrencilerden gelen sistematik ve yapılandırılmış geribildirimlerin önemini değerlendirmek ve bir programı şekillendirmedeki katkılarını tartışmaktır.Gereç ve yöntem: Değişen öğrenci profilleri ve öğrenme yönelimleri dikkate alınarak geribildirimlere göre yapılan bir ölçme değerlendirme yöntem değişikliğinin öğrenme üzerine etkisi izlenmiş; laboratuvar uygulamaları sonrasında yapılan kısa sınavların taze bilgiyi ölçmede, teorik bilginin pekiştirilmesinde etkin olduğu gözlemlenmiştir.Bulgular: Kısa sınav uygulaması, öğrencilerin öğrenim çıktılarının ne kadarını kazandıklarını ders kurulu sınavlarını beklemeden ölçmekte de kullanılabilmektedir. Böylece hedefin altında kalan başarı düzeylerinin arttırılmasına olanak sağlaması da kazanımlarından biridir.Sonuç: Bu tarz uygulamalarda geribildirimlerin öğrencilerin görev aldığı tıp eğitimi komisyonlarınca toplanıp değerlendirilmesi öğrenci perspektifinin objektif olarak yansımasını sağlamaktadır. Öğrencilerin değerlendirme süreçlerine dahil edilerek; profesyonellik, iletişim becerileri ve takım çalışmasında etkin rol alma gibi özelliklerin geliştirilmesi de ikincil ve uzun vadeli kazanç sağlamakta, bireysel ve mesleki gelişimlerini desteklemektedir.
Structure-Astringency Relationship of Anacardic Acids from Cashew Apple (Anacardium Occidentale L.)
Authors: Brito Edy , Mendes Liana , Garruti Deborah , Zocolo Guilherme , Lima Marcelo
Published: May 2020

Cashew apple presents a characteristic astringency. However, the compounds responsible for this characteristic were not described yet. A cashew apple extract was added to a BSA solution and the compounds before and after precipitation were analyzed by UPLC-QTOF/MSE. The extract astringency was measured on a 5-point scale (0: non astringent and 4: extremely astringent). Among the phenolics detected anacardic acids were identified and evaluated for their astringent effect. In the sensorial tests the cashew apple extract was considered very astringent (average of 2.5). A mixture of anacardic acids, had an average of 1.76 (astringent). The three isolated anacardic acids were evaluated. The in silicoexperiments were performed to analyze mainly the steric factor associated to the binding. The sensory results were confirmed by in silico analysis, indicating that a higher unsaturation degree of the aliphatic chain leads to an astringency increase.
Diverse Metal Coordination Center in M-N-C Enabling Different Type of Enzyme-Mimic Reactions
Authors: Chen Xinghua , Zhao Lufang , Zhou Qing , Xu Yuan , Zheng Yongjun , Shen Yanfei , Liu Songqin , Zhang Yuanjian
Published: May 2020

The epoch-making breakthrough of nanoscience has brought new perspective to empolder new generation of nanozymes with enzyme-like structure and further to propel the comprehending of the structure-property relationship. Here, we report that the regulation of metal coordination center in M-N-C nanozymes (M = Fe, Co, Mn, Ni, and Cu) greatly altered their biocatalytic activities so as to selectively drive different types of enzymatic reactions. It was revealed that the intrinsic selectivity in interaction and activation of ROS by different M-Nx was the origin to promote disparate types of enzyme-like reactions. This work would open a new vista of nanozymes to selectively catalyze different types of reactions, enabled by mimicking the molecular structure of natural enzymes and a further modulation.
In-Silico FDA-Approved Drug Repurposing to Find the Possible Treatment of Coronavirus Disease-19 (COVID-19)
Authors: Sharp Kumar , Dange Dr. Shubhangi
Published: May 2020

Identification of potential drug-target interaction for approved drugs serves as the basis of repurposing drugs. Studies have shown polypharmacology as common phenomenon. In-silico approaches help in screening large compound libraries at once which could take years in a laboratory. We screened a library of 1050 FDA-approved drugs against spike glycoprotein of SARS-CoV2 in-silico. Anti-cancer drugs have shown good binding affinity which is much better than hydroxychloroquine and arbidol. We have also introduced a hypothesis named “Bump” hypothesis which and be developed further in field of computational biology.
Classification of Platinum Nanoparticle Catalysts using Machine Learning
Authors: Parker Amanda J. , Opletal George , Barnard Amanda
Published: May 2020

Computer simulations and machine learning provide complementary ways of identifying structure/property relationships that are typically targeting toward predicting the ideal singular structure to maximise the performance on a given application. This can be inconsistent with experimental observations that measure the collective properties of entire samples of structures that contain distributions or mixture of structures, even when synthesized and processed with care. Metallic nanoparticle catalysts are an important example. In this study we have used a multi-stage machine learning workflow to identify the correct structure/property relationships of Pt nanoparticles relevant to oxygen reduction (ORR), hydrogen oxidation (HOR) and hydrogen evolution (HER) reactions. By including classification prior to regression we identified two distinct classes of nanoparticles, and subsequently generate the class-specific models based on experimentally relevant criteria that are consistent with observations. These multi-structure/multi-property relationships, predicting properties averaged over a large sample of structures, provide a more accessible way to transfer data-driven predictions into the lab.
Vitamin-mineral complexes as a protector of obstetric and perinatal complications (review of literature)
Authors: Pestrikova Tatyana Yu , Yurasova Elena A
Published: May 2020

Relevance. Despite the achievements of modern medicine, the problem of reducing complications of the gestational period and perinatal outcomes still does not lose its relevance. Lack of security and/or unbalanced consumption of vital micronutrients are factors of constant negative impact on health, growth, development and formation of organs and systemogenesis in all age periods. Unbalanced nutrition, in particular vitamin deficiency conditions, is considered by the World Health Organization as a problem of starvation, which has a direct impact on the incidence and mortality of the population. Aim. Analysis of literary sources to identify the effect of vitamin-mineral complexes on pregnancy and perinatal outcomes. Materials and methods. To write this review, we searched for domestic and foreign publications in Russian and international search engines (PubMed, eLibrary, etc.) over the past 30 years. The review included articles from peer-reviewed literature. Results. The review addresses balanced nutrition for pregnant women who receive close attention throughout the world. The optimal provision of vitamins and minerals for women during the gestational period, when the need for essential micronutrients is significantly increased, is a prerequisite for the physiological course of pregnancy and the full development of the fetus. This is especially important in the conditions of the northern and equivalent territories. The need for vitamins in women during pregnancy and lactation increases by 1.5 times, due to the intensive work of the endocrine system of women, the transfer of some nutrients to the fetus. Deficiency of certain vitamins is a risk factor for the development of birth defects, premature birth, and the birth of children with low body weight. Conclusions. The domestic combined vitamin-mineral preparation with micro and macro elements was created specifically taking into account the changing needs of the woman’s body for vitamins and minerals at different stages of pregnancy. Compatibility of components in 1 tablet is provided by special production technology.
Adenomyosis: focus on therapy
Authors: - -
Published: May 2020

Adenomyosis have an extremely negative impact on a woman's reproductive health. In the absence of drug therapy, the likelihood of surgical treatment increases which could be very traumatic for the patient and lead to a decline in infertility and onset of early menopause. That is why it is extremely important to start therapy in a timely manner, the most important method of which is hormonal treatment. The article discusses the efficacy and safety profiles of progestin dienogest.
Local angiogenic effects of hormonal contraception: literature review
Authors: Nabieva Kemalya R. , Burlev Vladimir A. , Mejevitinova Elena A. , Ilyasova Natalia A.
Published: May 2020

The processes of angiogenesis are one of the key in the functioning of the reproductive system in women. Studies on cyclic angiogenesis in the reproductive system have allowed us to single out a separate area of scientific research and to obtain results that have important scientific and practical value. The processes of cyclic angiogenesis in the organs of the reproductive system are studied in sufficient detail. At the same time, the issues of the influence of various methods of hormonal contraception on the relationship of angiogenic growth factors, hemostasis, regional hemodynamics remain unstudied. The assumption that such a relationship plays a significant role in the functioning of the endometrium, and modification of these factors can occur with various methods of exposure, including the appointment of hormonal contraception, can serve as a scientific research subject with a large practical component.
Morphological changes in the fallopian tubes in patients with ectopic pregnancy
Authors: Titova Galina P. , Damirov Mihail M. , Anchabadze Irina V. , Medvedev Alexandr A.
Published: May 2020

Relevance. Ectopic pregnancy is an urgent condition which may lead to intraabdominal hemorrhage and woman death. In recent years, the frequency of this pathology is significantly increasing. However, morphological changes in the fallopian tubes in patients with this disease remain understudied.

Aim. To study morphological changes in the fallopian tubes in patients with ectopic pregnancy with various variants of the clinical course.

Materials and methods. The morphological study included 130 patients who had laparoscopic surgery for ectopic pregnancy. Comprehensive morphological study of the fallopian tubes removed during surgery was conducted.

Results and discussion. The article presents the morphological changes in the fallopian tubes in patients with ectopic pregnancy. Implantation of a fertilized egg in the fallopian tube led to significant changes in its macro- and microstructure, which were due to invasion of the chorionic villi and involved all layers of the tube wall, differing only in depth and prevalence. The most pronounced morphological changes in various segments of the tube were revealed in the endosalpinx.

Conclusion. The combination of morphological changes in different layers of the tube is related to a chronic non-specific productive endomyosalpingitis with luminal deformation, which was one of the main causes of this disease development.
Biomarkers of cervicovaginal fluid for the diagnosis of cervical diseases associated with human papilloma virus (literature review)
Authors: Prilepskaya Vera N. , Mheryan Anna N. , Akopian Aida S. , Nazarova Niso M. , Dovletkhanova Elmira R. , Abakarova Patimat R. , Starodubtseva Natalia L.
Published: May 2020

Human papillomavirus (HPV) is one of the main pathogens of genital tract infections, which can lead to malignant transformation of cells of the cervix, vagina, vulva and anus. Approximately 90% of cervical intraepithelial neoplasia cases and 99% of cervical cancer cases occur in HPV-positive patients. However, the presence of HPV in the patients body can not be considered as a marker of progression or regression of the pathological process. The need to determine further tactics of examination and management of women with HPV-associated diseases of the cervix States the search for molecular genetic markers of neoplastic transformation in order to predict the risk of cervical neoplasia and cervical cancer. Diagnostic systems based on determination of biomarkers in cervicovaginal fluid (CVJ) can become convenient for application in clinical practice. The panel of CVJ proteins allows to make the exact characteristic of a condition of bodies of female reproductive system, including at neoplastic processes of a cervix of a uterus. The biomarkers identified in the CVJ can be used as informative tests to improve the accuracy of diagnosis of pathological changes in the cervix and to determine the risk criteria for the development of malignancy.