bluuebunny/crossref_metadata_2025 huggingface dataset:
Capivasertib (Truqap) for Breast Cancer
Authors:   Editors from The Medical Letter
Published: March 2024

The oral kinase inhibitor capivasertib (Truqap – AstraZeneca), a first-in-class AKT inhibitor, has been approved by the FDA for use in combination with the selective estrogen receptor degrader (SERD) fulvestrant (Faslodex, and generics) for treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer in adults with one or more PIK3CA/AKT1/PTEN-alterations who had disease progression on at least one endocrine-based regimen for metastatic disease or recurrence on or within 12 months of completing adjuvant therapy.
Airsupra: An Inhaled Albuterol/Budesonide Combination for Asthma
Authors:   Editors from The Medical Letter
Published: March 2024

The FDA has approved Airsupra (AstraZeneca), a metered-dose inhaler containing the short-acting beta2-agonist (SABA) albuterol and the inhaled corticosteroid (ICS) budesonide, for use as needed for treatment or prevention of bronchoconstriction and to reduce the risk of exacerbations in patients ≥18 years old with asthma. Airsupra is the first combination of a SABA and an ICS to become available in the US. It is not approved for use as maintenance therapy.
In Brief: A New OTC Naloxone Nasal Spray (RiVive)
Authors:   Editors from The Medical Letter
Published: March 2024

The FDA has approved RiVive (Harm Reduction Therapeutics), a 3-mg naloxone nasal spray, as an over-the-counter (OTC) product for emergency treatment of opioid overdose.1 Two 4-mg naloxone nasal spray formulations, Narcan and one of its generics, were approved for OTC sale in 2023.
Drugs for Bipolar Disorder
Authors:   Editors from The Medical Letter
Published: March 2024

Bipolar disorder is characterized by episodes of mania, hypomania, and depression. Recurrences of manic or (more frequently) depressive symptoms are common. About 15-20% of patients with bipolar disorder die by suicide.
Omalizumab (Xolair) for Food Allergy
Authors:   Editors from The Medical Letter
Published: March 2024

Omalizumab (Xolair – Genentech), a recombinant anti-IgE monoclonal antibody FDA-approved for treatment of allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic urticaria,1,2 has now also been approved for use in conjunction with food allergen avoidance to reduce IgE-mediated food allergic reactions caused by accidental exposure in patients ≥1 year old. Omalizumab is the first drug to be approved in the US to reduce allergic reactions to more than one food. Palforzia, an oral peanut allergen powder, was approved in 2020 to mitigate allergic reactions caused by accidental peanut exposure in patients with a confirmed peanut allergy.
THE CHILDREN'S RIGHTS DOCUMENT IN THE OVERVIEW SIGN OF THE CRDTl (2024)
Authors: de Araújo Alexandre Gentil Corte-Real
Published: March 2024

Introduction: In general, to analyze Article 18 of the Constitution of the Democratic Republic of Timor-Leste (CRDTL), which says that all children have the right to education, health, etc. We return to the condition of children who form their concern, when the conditions become aggravated as child labor, and lose their rights on the part of the family. Sometimes, children cover the sadness and used the other way to help the needs of the family, but the children's opinions should be heard all matters relating to their rights is fundamental. Objectives: To narrate and review to ensure equal access and educational opportunities for all children and to identify and meet requirements that allow for the development of their capacities or aptitudes and their culture in each municipality of Timor-Leste. Methodology: Elaborated in the elaboration of deductive, based on research work in international articles of literary and legislative scholarly, whose current documentary sources will be cited in the bibliography. Conclusion: To be achieved to ensure the law of the constitution RDTL says, that the protection of children is the compression to respect the dignity of children, so with promises to be the well-being of children and also their protection against any way at risk and to enforce the right of children to seek the search for children. The solution that promotes the greatest possible benefit to children, also interprets and carries out a norm, should be inthe best interests of children. Therefore, parents have a responsibility to guarantee the rights of children and to develop with the freedom of justice and equality, such as the participation of 17-year-old minorities to have some educational resources and learn from anythingwith joy. And satisfaction of each child or minorities cited by (Corte Real AG & Babo Soares D.C., 2024).
PENGARUH PERUBAHAN TATAGUNA LAHAN TERHADAP KINERJA SALURAN DRAINAE STUDI KASUS DESA LABANGKA
Authors: Imansyah Adin Fikri , Najimuddin Didin , Israjuna Israjuna
Published: March 2024

Akibat danya perubahan tata guna lahan di pulau Sumbawa saat ini mengalami penurunan debit air sebesar 32% dikarenakan intensitas hujan menurun akibat dari itu tanaman padi mengalami gagal panenen. Untuk mengatasi intensitas hujan yang kurang tersebut maka dioptimalkan drainasi pada derah irigasi sehingga kecepatan air meningkat dan resapan air tanah menurun. Rancangan saluran dranasi untuk mengalirkan air ke petak persawahan sangat tepat dikarenakan air yang mengalir bisa terbagi maksimal. Masalah utama yang yang dirasakan akibat penutupan lalahan tersebut adalah bagaimana menjaga agar umur layanan bangunan sesuai dengan apa yang direncanakan. Adanya penggundulan hutan pada daerah pengaliran sungai dan perubahan fungsi lahan menyebabkan terjadinya erosi pada tanah sekitar, sehingga mempercepat pendangkalan pada saluran hal ini disebabkan oleh rusaknya saluran sehingga terjadinya rembesan disamping itu juga tidak ada pemeliharaan saluran. Dari hasil peneitian menyimpulkan bahwa kondisi saluran draenase labangka debit airnya adalah 0,109 m3/det, dengan luas penampang saluran 2,021 m2 dengan kecepatan rata – rata 0,24 m/det.Adapun cara penangulaganya adalah dengan cara normalisasi saluran drainase dan pembuatan saluran beton.
REDESAIN TUNGKU PEMBAKARAN BATU BATA MENGGUNAKAN BAHAN BAKAR KAYU DAN SEKAM PADI
Authors: Rifandi Agus , Zulkarnaen Zulkarnaen , Nuraini Eni
Published: March 2024

Batu bata merupakan bahan bangunan yang sangat akrab bagi masyarakat, baik masyarakat perkotaan ataupun pedesaan. Bahan bangunan ini juga mudah diperoleh dengan harga yang bervariasi. Karena hal inilah, batu bata masih menjadi primadona bahan konstruksi dibanding dengan material lain dengan fungsi yang sama. Dari seluruh proses pembuatan batu bata,  tahap pembakaran adalah tahap yang paling menentukan berhasil tidaknya usaha ini. Dengan desain tungku pembakaran yang sudah ada saat ini, baik bahan bakarnya menggunakan kayu atau sekam padi pada umumnya kerusakan batu bata dalam proses pembakaran sekitar 20% sampai 30% (Tamrin, 2008). Dengan mempertimbangkan hal yang telah disampaikan diatas, maka ridesain Tungku Pembakaran Batu Bata sangatlah tepat. Karena perlu adanya usaha untuk mengurangi persentase kerusakan dan energy yang digunakan. Metode yang digunakan untuk mencapai desain akhir yaitu survei lapangan, pengumpulan data, analisa data, konsep dan desain akhir. Dari hasil studi pustaka tentang tungku pembakaran digunakan tungku dengan model tungku dengan api berbalik atau pada bagian atas dibuat melengkung. Untuk posisi penyusunan batu bata ketika pembakaran dibuat jarak 5,5 cm antar batu bata dalam 1 baris dan jarak 5 cm antar baris, dengan tujuan agar radiasi panas dapat merata  sehingga dapat menekan persentase kerusakan batu bata pada saat pembakaran. Dari hasil analisis diperoleh waktu pembakaran menggunakan bahan bakar kayu selama 17,6 jam, yang berarti dari waktu pembakaran menggunakan tungku konvensional selama 4 hari dapat menghemat waktu selama 78,4 jam, atau sama dengan 81,67 %. Dan hasil analisis menggunakan bahan bakar sekam padi diperoleh waktu 14,43 jam, yang berarti dari waktu pembakaran menggunakan tungku konvensional selama 7 hari dapat menghemat waktu selama 153,57 jam, atau sama dengan 91,41 %.
Analisis penerapan akuntansi pertanggungjawaban sebagai alat penilaian kinerja pusat biaya pada Perusahaan Daerah Air Minum (PDAM) Kabupaten Tana Toraja
Authors: Pala’langan Eri Novayanti , Saerang David Paul Elia , Tirayoh Victorina Z.
Published: March 2024

Responsibility accounting is a system that is arranged in such a way according to the nature and activities of the company with the aim that each organizational unit can be accountable for the results of the activities of the unit under its supervision and can be used by the company to assess the performance of managers, especially the cost center. The application of accountability accounting can be said to be good if the conditions of its application are met. The requirements of accountability accounting are organizational structure, budget preparation, classification of controlled and uncontrolled costs, classification of account codes, and accountability reports. The purpose of this study was to determine the application of responsibility accounting in assessing the performance of the cost center at the Regional Drinking Water Company (PDAM) of Tana Toraja Regency. The analysis method used in this research is descriptive method which aims to describe the data that has been collected as it is obtained from the results of interviews and data collected from the company. Based on the results of the study, it shows that the application of accountability accounting in the performance assessment of the cost center at the Regional Drinking Water Company (PDAM) of Tana Toraja Regency is not good enough, because in the company's accountability report there are still costs that are combined into one account that should be classified. The company has also not implemented a clear and firm reward and punishment system.
Evaluation of Safety of 9- and 6-Month Treatment Regimens in Patients with Rifampicin-Resistant Tuberculosis in the Republic of Belarus
Authors: Yatskevich N. V. , Gurbanova E. , Gurevich G. L. , Skryagina E. M.
Published: March 2024

The objective: to evaluate the safety of 39- and 24-week treatment regimens in the patients with rifampicin-resistant tuberculosis (RR-TB).

Subjects and Methods. Cohorts of patients with RR-TB were treated with the following regimens: 550 patients received modified short course treatment regimens (mSCT), and 139 patients were treated with BPaLM regimen. Serious adverse events (SAEs) and adverse events of special interest (AESI) of grade 3 or higher were assessed according to the EndTB Severity Grading Scale, Version 5.

Results. In mSCT cohort, 113 SAEs were reported, in BPaLM cohort, 12 SAEs were reported, at least 1 SAE was reported in 16.0% and 7.2% of patients, respectively. In mSCT cohort, 37 AESI were reported in 5.8% of patients. Of the 150 SAEs/AESI reported in mSCT cohort, 78.7% have resolved, 4.0% are being resolved, 0.7% have resolved with sequelae, and 2.7% have not resolved. Of the 12 SAEs in BPaLM cohort, 66.7% have resolved, 16.7% are being resolved, and 8.3% have resolved with sequelae. Drugs were discontinued in 16.8% of SAEs, 8.1% of AESI in mSCT cohort, and 25.0% of SAEs in BPaLM cohort. In mSCT cohort, 21 patients died during treatment, only in 6 patients the influence of anti-tuberculosis drugs on the fatal outcome could not be ruled out, in 15 cases there was no such a correlation. In BPaLM cohort, 1 patient died due to progression of concomitant cancer.

Conclusions. SAEs/AESI rarely occur with mSCT and BPaLM regimens and rarely lead to treatment discontinuation. Appropriate monitoring and management of SAEs/AESI is an important component of clinical practice.
SHAKESPEARE BEING GLOCAL: A COMPARATIVE STUDY OF SHAKESPEARE’S ‘HAMLET’ AS BHARDWAJ’S ‘HAIDER’
Authors: Mustabshira Siddiqui
Published: March 2024

The present article compares and contrasts Shakespeare's Hamlet with the 2014 film Haider, directed by Vishal Bhardwaj, which sheds light on the unseen aspects of the 1989 insurgency in Jammu and Kashmir. The movie not only focuses on Jammu and Kashmir but also presents an ingenious point of view that connects us with the real drawbacks of human society. Hamlet is not only about revenge; it is about the theme of the disappearance of King Hamlet, where Prince Hamlet is pretending to be insane to trap his uncle. It is also about the corruption that prevailed in Denmark and the sufferings that the women had to go through. The plot of Denmark is replaced in Haider by the plot of the Kashmir conflict in 1995 and enforced civil disappearances. The characters are given new shades according to contemporary Kashmir.
THE NEED FOR COMPARABLE CORPORA IN TRANSLATION TEACHING AND LEARNING
Authors: Iris Klosi  , Ergys Bezhani
Published: March 2024

The primary objective of this research is to catalyze the scholarly progress of translation teaching and learning within higher education institutions in Albania, specifically in the preparation of students in the field of translation theory and practice. The study aims to contribute significantly to the theory and practice of translation by emphasizing the imperative to develop comparable corpora of English-Albanian texts across diverse text types. Additionally, the research will delve into establishing a typology of translation strategies in Albania. Building upon the pioneering efforts of the researchers in previous work, which involved the translation of English and Albanian texts using linguistic, stylistic, and semantic techniques, this study also pays meticulous attention to the intricate relationship between the translation process and its resulting product. By focusing on the development of comparable corpora, this research presents a valuable opportunity to enhance both the theory and practice of utilizing bilingual corpora in the context of translation teaching, learning, and research. The outcomes of this research endeavor will provide the foundational framework for the future formulation of a streamlined pedagogical typology specifically addressing the use of comparable corpora in teaching and learning translation strategies in the English-Albanian context. This typology, once developed, will further serve as the basis for generating a series of project concepts with the overarching goal of establishing cooperative agreements. These agreements are envisioned to foster collaboration in the future with colleagues from regional and Western universities, as well as with researchers and experts in the field of translation.
Christianization of Akpéma and Kondona Initiation Rites and Their Desecration by the Catholic Church in the Prefecture of Kozah in Northern Togo
Authors: TCHELEGUE Nadiedjoh , TCHABLE Boussanlegue , AMOUZOUVI Dodji
Published: March 2024

The objective of this research is to examine the impact of the celebration of akpéma and kondona rites in church on their sacredness. The survey covered 80 people, including 25 catholic priests and 55 guarantors of Kabyè habits and customs, through to purposive sampling. Direct observation, individual interview and documentary research are the data collection techniques used. The data collected was subject to content analysis. The results indicate that upon entering the church, the akpéma and kondona rites were remodeled, losing everything that founded their sacredness: the eponymous ancestor, the sacred place, the mythical time, the founding myths, the bloody sacrifices, the person of the celebrant (cojo) and his verbal words. However, some new landmarks allow us to note an attempt at their resacralization by the church.
Book Review ‘Real Estate Management: A Management Approach’
Authors: Iqbal Uqbah
Published: March 2024

The main function of the property manager is to realize the property owner's objectives, to generate income for them as well as maintain or increase the value of the investment property. The job of a property manager is complex and requires expertise in a more comprehensive field of real estate. The real estate market which has a direct impact on the job of real estate managers, is a major component of the economy in general. The two are very close where economic performance can cause changes in the real estate market. In order to assess the current and future potential of a particular property and then develop a management plan for it, a property manager must first understand the underlying economic trends and their implications for the real estate market. Only then can the property manager proceed with the steps to develop an efficient and professional management plan. All the activities involved in the marketing of the space to be rented are directed towards a single goal, which is to sign a rental agreement between the owner and the tenant. The role of the property manager in rental management will involve aspects of rent collection, establishing good relations between owners and tenants, coordination between tenant contractors, management of utilities and building services and monitoring the return of the premises to a good condition after the termination or expiration of the rental period.
AFRIMA Model Forecast Performance: An Empirical Study using Naira-Yuan Exchange Rate
Authors: Amaefula Chibuzo G. , Oputa Onyinemi O.
Published: March 2024

In financial time series and econometrics, some macroeconomic variables exhibit long memory features that may not be best described using short memory models like ARIMA. This paper, however, is structured to compare different fractional integration in AFRIMA forecast performance for the Naira-Yuan exchange rate. The empirical monthly data set used covered the period from January 1981 to December 2022. Fractional integration test are based on the ADF unit root test and the auxiliary autoregressive order three (AAR(3)) order of integration test. Model estimation is support by the Marquart algorithm for calculating least squares estimates and performance comparison is based on the Amaefula forecast criterion (AFC). The result specified that AFRIMA (1, d, 1) where I(d = 0.07891) is more appropriate and has the best forecast performance compared to others. The result also reveals that AFRIMA model yield better and more precise forecasts when fractional integration is closer to zero that is, I(d→0) than when I(d→½). Therefore, AFRIMA models can be useful in studying exchange rate dynamics for risk-averse and risk incline in times of investment and profitability in the long-run.
Effects of Tredmil Training with and without Mirror Therapy on Lower Limb Function, Dynamic Balance, and Gait in Chronic Stroke Patients
Authors: Ali Qasim , Long Yang , Ali Muhammad
Published: March 2024

Stroke, a brain attack, causes approximately 17 million new strokes annually, leading to motor deficits in up to 80% of patients, 30% experiencing long-term deficits in independent walking, and two-thirds experiencing functional limitations in lower limbs. The objective of this research is to determine the effect of treadmill training with and without mirror therapy on lower limb function, dynamic balance, and gait in chronic stroke patients. This research involved 24 chronic stroke patients divided into two groups: Group A received lower-limb treadmill training with mirror treatment, and Group B received treadmill training without mirror treatment. Both groups received traditional physiotherapy methods. The study found that MAS was non-parametric, while other measures were parametric. The trial lasted eight weeks, using six-minute walk testing, the modified Ashworth scale, and Fugl-Meyer assessment (lower extremity). The study found that the "mirror therapy" group had better results than the "control group" group, with P values of 0.023 and 0.00, respectively, for the outcome measures "MAS post-intervention" and "6MWT post-intervention." The "Mirror Therapy" group also improved more than the "Control Group" group in the outcome measure "FMA-LE Post-Intervention."This study concluded that there was a significant association between treadmill training and mirror therapy and lower limb functioning, dynamic balance, and gait in chronic stroke patients.
Review: Parasite Strategies to Escape Attack by The Immune System of Their Hosts
Authors: Jari Sawsan Darweesh
Published: March 2024

This review aims to investigate the parasitic strategies that enable them to escape attack by the immune systems of their hosts and cause infection. A parasite is a creature that obtains its sustenance and other requirements from a host, which is another organism that provides support to the parasite. Medical parasitology encompasses protozoa, helminths, and some arthropods. Parasitic diseases lead to host immune responses that expel the infesting parasites. Parasites also have improved a number of strategies to prevent host immune attacks and survive in the environment of the host. In this study, all information about the parasites abilities to avoid host complement immune attack in a hostile environment and the mechanisms of complement immune evasion is provided.
New paper: “Wikidata subsetting: approaches, tools, and evaluation”
Authors: Willighagen Egon
Published: March 2024

Just before the end of the year, the

Wikidata subsetting: approaches, tools, and evaluation

paper by Seyed Amir Hosseini Beghaeiraveri

et al.

got published (doi:10.3233/SW-233491). I am really excited our group (i.e. Ammar and Denise) has been able to contribute to this. I think it also is a great example of the power of hackathons to bring together people.
New paper: “WikiPathways 2024: next generation pathway database”
Authors: Willighagen Egon
Published: March 2024

This week the next WikiPathways NAR Database issue paper was published (doi:10.1093/nar/gkad960). It is the next paper in a series of papers about the evolution of the Open Science project for making biological pathways available in a Open and FAIR way. This year, it described that significant move away from MediaWiki.
American Chemical Society Fall 2023 meeting
Authors: Willighagen Egon
Published: March 2024

About four weeks ago the Fall 2023 American Chemical Society meeting (#ACSFall2023). I have attended a few ACS meetings in person and even organized a symposium at the 2010 ACS meeting in Boston. This time too, I did not participate in person, tho visiting San Francisco again would have been nice. I gave two presentations (slides doi:10.5281/zenodo.8255394), but have not uploaded my slides of the first presentation to Zenodo yet.
The effect of exercise on quality of life, fatigue, and pain management in older women: A cross-sectional study in Greece
Authors: Theofilou Paraskevi , Papaemmanouil Konstantina
Published: March 2024

Background: Frequently, the contribution of exercise to the elderly and the associated benefits of such activities are discussed. Aim: This paper deals with the contribution of exercise to the levels of quality of life, fatigue, and pain management. Method: Then, quantitative and cross-sectional research is carried out to investigate the contribution of physical exercise to the levels of quality of life, fatigue, and pain management in women over 60 years of age. For the data collection, the questionnaire used consisted of the Missoula—VITAS Quality of Life Index (MVQOLI), the Pain Assessment Questionnaire (PSeQ), and the Fatigue Assessment Scale (FAS). Results: From the statistical analysis made between exercise and quality of life, fatigue, and pain management of the women over 60 who participated in the research, it follows that women undergoing exercise show a better quality of life and less fatigue, while no statistically significant difference was detected in terms of pain management. Conclusion: It seems that exercise affects positively quality of life and fatigue. Potential implications must be addressed in order to organize more exercise programs, particularly for older people.
Pengaruh Kompensasi, Motivasi dan Lingkungan Kerja Terhadap Kinerja Karyawan
Authors: Nurjanah Nunu , Parashakti Ryani Dhyan , Perkasa Didin Hikmah
Published: March 2024

Persaingan antar perusahaan di era globalisasi semakin tajam, pengembangan sumber daya manusia merupakan cara utama untuk memenangkan kompetisi global. Perusahaan memerlukan sumber daya manusia yang berkualitas yang menghasilkan kualitas kerja yang baik. Tujuan dari penelitian ini untuk menguji pengaruh kompensasi, motivasi, dan lingkungan kerja terhadap kualitas kerja kayawan,Penelitian ini bertujuan untuk menguji pengaruh kompensasi, motivasi kerja, dan lingkungan kerja terhadap kinerja karyawan yang signifikan terhadap kinerja karyawan pada PT. Cipta Nugraha Utama Teknik pengumpulan data menggunakan data primer berupa kuesioner yang menggunakan skala likert dalam pemilihan respon penilaian, sedangkan teknik analisis data menggunakan analisis regresi linear berganda. yang melibatkan karyawan sebanyak 58 responden. Dari hasil penelitian menunjukkan bahwa: Kompensasi, Motivasi, dan lingkungan kerja secara simultan berpengaruh signifikan terhadap kinerja karyawan dan secara parsial kompensasi, motivasi, dan lingkungan kerja berpengaruh signifikan terhadap kinerja karyawan, Saran yang dapat diberikan agar perusahaan memperhatikan kompensasi yang diberikan, pengabdian yang dilakukan oleh karyawan, serta kenyamanan karyawan dalam bekerja.
Pengaruh Ukuran Perusahaan, Leverage dan Capital Intensity Terhadap Tax Avoidance
Authors: Dara Dara , Kamil Islamiah
Published: March 2024

Tujuan penelitian adalah untuk mendapatkan bukti empiris tentang pengaruh variable independen terhadap variable dependen. Variabel independen yang digunakan pada penelitian ini adalah ukuran perusahaan, Leverage, Capital Intensity. Sedangkan variabel dependennya adalah penghindaran pajak. Perusahaan yang digunakan dalam penelitian ini adalah perusahaan manufaktur sub sektor industry dasar dan kimia yang terdaftar di Bursa Efek Indonesia (BEI) dari tahun 2016 hingga 2020. Jumlah sampel dalam penelitian ini adalah 48 perusahaan dengan total 240 data penelitian. Metode pengambilan sampel menggunakan purposive sampling dan penelitian ini menggunakan analisis regresi linear berganda untuk menguji hipotesis. Hasil penelitian menunjukkan bahwa ukuran perusahaan berpengaruh terhadap penghindaran pajak. Leverage pengaruh positif terhadap penghindaran pajak dan Capital Intensity berpengaruh negatif terhadap penghindaran pajak.
Pengaruh Kompensasi, Beban Kerja dan Motivasi Terhadap Kinerja Karyawan
Authors: Aditiawati Evita , Parashakti Ryani Dhyan
Published: March 2024

Human Resources (HR) are individuals who work as movers of an organization, both institutions and companies and function as assets that must be trained and developed capabilities. The phenomenon in this study is the problem of employee performance which has an impact on decreasing sales levels. Based on the observations of researchers in the field that the decline in employee performance is caused by several things, namely compensation, motivation and workload. The purpose of this study is to analyze the effect of work compensation on employee performance. To analyze the effect of workload on employee performance. To analyze the effect of work motivation on employee performance. In this research proposal using quantitative methods. Data collection using questionnaires, a number of questions were made to be filled out by respondents. This research is classified as associative research, which is research that looks for causal relationships or influences, namely the relationship between the independent variable (X) and the dependent variable (Y). The population in this study is all employees who work PT. Karya Sejati Indonesia numbered 75 people. The sampling technique used is saturated sampling, that is, the number of samples used as a whole. The method used in this study is to use the Partial Least Square (PLS) method. Based on the results of Compensation has a positive and significant effect on employee performance. Workload does not affect employee performance so further research is needed.And work motivation has a positive and significant effect on performance.
Pendampingan Manajemen Bisnis Dan Digital Marketing Bisnis Pada Usaha Bakery “Byfa Cake”
Authors: Soleha Erin , Hidayaty Dwi Epty , Permana Indra , Hidayah Zulfa Zakiatul
Published: March 2024

Usaha Mikro Kecil dan Menengah (UMKM) sangat berperan dalam perekonomian masyarakat Indonesia, selama ini yang banyak berperan dalam penyerapan tenaga kerja dan pemerataan perekonomian di Indonesia. Beberapa permasalahan yang kerap terjadi di UMKM adalah kesulitan pemasaran, keterbatasan SDM, kesulitan bahan baku, keterbatasan inovasi dan teknologi serta keterbatasan pembiayaan. Oleh karena itu, dibutuhkan pendampingan terhadap para pelaku UMKM. Pendampingan manajemen bisnis dan digital marketing bisnis adalah suatu bentuk bantuan atau dukungan yang diberikan kepada Usaha Mikro, Kecil, dan Menengah (UMKM) dalam mengoptimalkan proses produksi hingga meningkatkan volume penjualan. Saat ini, UMKM merupakan sektor penting dalam perekonomian karena memberikan dampak besar yang positif terhadap pertumbuhan ekonomi, menciptakan lapangan kerja, dan menggerakkan roda perekonomian di daerah.  Dalam kegiatan pengabdian ini, Byfa Cake sebagai mitra. Byfa Cake memproduksi kue kering dan kue basah yang berada di daerah Cikarang Utara Kabupaten Bekasi Jawa Barat.
Analisis Risiko Investasi Saham Melalui Diversifikasi Portofolio Secara Domestik Dan Internasiaonal
Authors: Nuraini Niken Paramitha , Simatupang Wilmar , Dasman Sunita
Published: March 2024

Penelitian ini untuk mengetahui risiko investasi melalui diversifikasi portofolio secara domestic dan internasional. Dengan seiring perkembangannya di era globalisasi dan percepatan pertumbuhan ekonomi, penanaman modal dapat dilakukan pada berbagai jenis instrumen investasi yang relatif berisiko tinggi , seperti saham pasar modal dalam negeri. dan pasar modal internasional. Berinvestasi pada saham merupakan salah satu pilihan investasi yang menjanjikan keuntungan tinggi dengan risiko tinggi. Oleh karena itu, penulis ingin memperdalam pembahasan mengenai penilaian risiko yang terkait dengan investasi internasional. Tujuan dari penelitian ini adalah untuk mengetahui risiko pada saham melalui diversifikasi portofolio nasional internasional.Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif. Teknik analisis yang digunakan adalah analisis studi literatur.
The Influence of Debt to Equity Ratio (DER) and Return on Assets (ROA) on Share Prices in Property & Real Estate Sector Companies Listed on the Indonesian Stock Exchange for the 2013-2017 Period
Authors: Dewi Puput Saputri , Sapruwan Muhammad
Published: March 2024

In The purpose of this research was to determine the effect of debt to equity ratio and return on assets on stock price. The samples used were 17 property & real estate sector companies listed on the Indonesia Stock Exchange in 2013-2017. The sample technique used was purposive sampling. This study uses secondary data in the form of published annual reports. The methods used in this study are descriptive statistical analysis, classical assumption test, multiple linear regression, t test, F test and coefficient of determination test. The data was processed using SPSS Version 23. Based on the results of the study it is known that partially the debt to equity ratio has no effect on stock price and return on asset effects stock price, while simultaneously to equity ratio and return on asset effects stock price..
Leishmaniasis cutánea y mucocutánea
Authors:   Fundación Universitaria Autónoma de las Américas, Peláez Cardona David , Restrepo Montoya Valentina ,   Universidad Tecnológica de Pereira
Published: March 2024

Femenina de 22 años, previamente sana, residente de la ciudad de Pereira quien migra al área rural del municipio de Mistrató, Risaralda, por cuestiones laborales. Consulta al servicio de salud por cuadro clínico de 1 mes de evolución consistente en aparición de pápula eritematosa en dorso de muñeca derecha con posterior ulceración de esta.
For a Postcolonial reading of the EU
Authors: Zevounou Lionel
Published: March 2024

The use of the terms 'decolonial', 'postcolonial' and 'race' has become fashionable, particularly in Anglo-American legal scholarship. However few legal scholars in recent years have ventured into postcolonial approaches to European Union law. I will argue that one cannot understand the history and law of the European Union if one fails to understand and acknowledge colonialism.
Colonialism and EU Law
Authors: Eklund Hanna
Published: March 2024

In 1957, when the Treaty of Rome was signed and founded what later became the European Union (EU), four out of six of the original Member States were colonial powers. An important methodological question for EU law research is how this historical fact has affected the development of EU law. I argue that answering the question of how Europe’s centuries long history of colonialism has shaped EU law is not just a historical exercise but also a starting point for an examination of EU law of today.
Interlevensbeschouwelijke geestelijke verzorging
Authors: Liefbroer Anke , Alma Hans , Coppens Pieter
Published: March 2024

De bundel belicht hoe geestelijk verzorgers levensbeschouwelijke diversiteit navigeren door interlevensbeschouwelijke competenties te ontwikkelen, gebruikmakend van theorie, praktijkvoorbeelden en reflectie. Het verkent de rol van eigen levensbeschouwing in cliëntbegeleiding en methodes voor effectieve gespreksvoering. Bedoeld voor studenten en ervaren verzorgers, biedt het handvatten voor professionele ontwikkeling binnen een veelkleurige levensbeschouwelijke context.
Gravedad Modificada
Authors: González Palazón Ramón
Published: March 2024

Catálogo de la Exposición celebrada del 14 de diciembre de 2022 al 28 de febrero de 2023, en Sala La Capilla, Rectorado de la Universidad de Murcia. Organizado por el Servicio de Cultura. Gravedad modificada podría ser considerada una instalación “cosmológica”: En efecto, todo el que se mide con el universo o con nuestra finitud no puede más que plantear su propia imagen del “cosmos”, que desde Pitágoras designa el conjunto de las cosas y el orden que las gobierna. El sistema construido en la capilla del Edificio de la Convalecencia en Murcia se descubre, en primer lugar, como una intervención site specific, pues pretende honrar la mística del lugar, aspirando a símbolos de carácter universal. Sus elementos son tres: una esfera (Opus), que se alza ingrávida en el centro de la estancia, protagonizando la escena; dos pilares verticales (Unitas) a los lados, de los que emana luz; y un conjunto de piedras, que descansan grávidas bajo la esfera y en un pequeño reducto tras la misma. Intuitivamente son interpretados como una dimensión celeste frente a la más terrenal, permaneciendo los elementos verticales quizás como puente y faro entre dos mundos contrapuestos.
Utilization of Engineering Management Principles in the Adoption of Solar Energy in Iraq
Authors: Alboahmed Ahmed K. , Gümüş Tuğbay Burçin
Published: March 2024

This article explores the application of engineering management principles to overcome energy challenges in developing countries, focusing on Iraq's energy sector. It examines the current situation, challenges, and potential of solar energy in Iraq. The article introduces the topic, reviews relevant literature, and discusses the evolution of Iraq's electricity sector. It highlights challenges and proposes solar energy as a solution. The study evaluates the state of solar energy in Iraq, emphasizing its contextual suitability and potential impact. The research methodology, data analysis, and key findings are outlined, ensuring rigor and validity. The role of engineering management principles in adopting solar energy is explored. The conclusion summarizes research outcomes, offering recommendations for policymakers, stakeholders, and researchers to enhance solar energy benefits in Iraq.
Pendampingan Peningkatan Keterampilan dan Pemasaran Hasil Kerajinan Limbah Kain Berbasis ICT pada KWT Salimah Nagari Sungai Abang Lubuk Alung
Authors: Dahri Nuraeni , Sutardjo Agus , Weriza Jusmita , Hadi Harry Setya , Rinaldo Jhon , Adawiyah Dina
Published: March 2024

The purpose of providing assistance through PKM activities is to improve the skills of craftsmen in making products from fabric waste and ICT-based marketing systems in the KWT Salimah craftsmen group in Sungai Abang Lubuk Alung nagari. The PKM method used is education with a lecture-discussion approach and Learning By Doing through practical work. Counselling assistance on how to use digital devices to market and increase the sales volume of KWT Salimah merchandise which has only been done conventionally or offline. This counselling contains education about using digital devices wisely and appropriately and creating social media and e-commerce whose designation is to sell online creatively. The results obtained from this extension activity are the increase in digital knowledge and skills of KWT Salimah members regarding digital literacy, information, and media as well as a change in mindset about business in the industrial era 4.0. Increased knowledge and skills in processing fabric waste with new products that are directly practised can be achieved. The results of this PKM service can also improve and increase the knowledge and skills of KWT Salimah members in developing a fabric waste handicraft business which can have an impact on improving the household economy of residents of Sungai Abang nagari, Lubuk Alung Padang Pariaman
تصدير المعرفة في القانون الوضعي فقهاً وقضاءً
Authors: الخفاجي أ. متمرس د عزيز كاظم جبر , عادل بدر علوان
Published: March 2024

لتصدير المعرفة القانونية سواء كانت عند الفقيه أم لدى القاضي, لابد من اتباع أحد مذاهب نظرية المعرفة في تقديم الدليل على كل ما يمكن تحصيله من معرفة. وهذا الدليل هو الذي يثبت التحصيل المعرفي وصحته، ولا يكون اختيار المذهب المعرفي في التحصيل بناءً على رغبة شخصية أو ميل ذاتي لدى الباحث؛ وإنما طبيعة البحث العلمي هي التي تفرض عليه الدليل وكيفية تحصيل المعارف منه.

     فاتباع المذهب العقلي أو المذهب الوضعي في الاستدلال يكون محكوماً بطبيعة موضوع الاستدلال. والبحث في وقائع مادية للوصول إلى الحكم الأقرب للواقعة يستلزم استقراء تلك الوقائع المعروضة, وصوغ الحكم الأقرب إليها مما ينتجه الدليل الاستقرائي، بينما تطبيق النص على واقعة معينة بذاتها, لا يمكن العمل به إلا بمقتضى الدليل العقلي. وتختلف طبيعة التحصيل المعرفي بين كل من القاضي والفقيه بحسب الغاية التي ينشدها كل منهما.
عمليـات المصـارف الشـاملـة من الوجهـة القـانونيـة
Authors: ا. م. د. علي طلال هادي
Published: March 2024

إن عمليات المصارف الشاملة بدأت تأخذ مجالاً واسعًا في الآونة الأخيرة, نتيجة زيادة الاستثمارات والحركة التجارية التي تتطلب سيولة مالية يحصل عليها المستثمر أو التاجر من المصرف، و ينبغي على الأخير, مزاولة العمليات المصرفية برمتها, ابتداءً من العمليات المصرفية التقليدية المتمثلة بالحسابات والائتمانات والخدمات المصرفية والعمليات المصرفية الاستثمارية المتمثلة بخدمات التأجير التمويلي, وإدارة محافظ الأوراق المالية وتمويل المشاريع الاستثمارية للعملاء أو المضاربة في الأوراق المالية لصالحهم, وأن مزاولة المصارف الشاملة لهذه العمليات, يقتضي مراعاة الوسائل القانونية التي تكفل حماية العميل وهي سرية الحسابات المصرفية والالتماس بالوصايا والإفلاس ومسؤولية المصرف تجاه العميل.
الأبعـــادُ الاقتصاديّة والاجتماعيّة للسياحةِ الدينيّة فِي العراقِ _ دراسة مقارنة
Authors: أ.د سحر جبار يعقوب  , الكلابي صلاح حسن عبود
Published: March 2024

للسياحة باختلاف أنواعها ومنها السياحة الدينية دور هــام في الجوانب الاقتصادية والاجتماعية للدول، ويتبين الأثر الاقتصادي عن طريق زيادة أرصدة النقد الأجنبي في البلاد عبر الانفاق السياحي والاستثمار الأجنبي , فضلاً عن الهبات والتبرعات وما سواها، أما آثارها الاجتماعية مكزفتبـدو واضحة في إمكانية إعـــادة توزيع الدخل من قبل الدولة ودعم أصحاب الدخول المنخفضة وتوفير فرص العمل ومعالجة مشكلة البطالة، فضلاً عن زيادة الوعي الثقافي لدى الأفــراد وعدّ مرافق السياحة الدينية جزءًا من الموروث الحضاري , ودفع عجلة التنمية القومية، وهذا يدفع الإدارة للاهتمام ببقية أنواع السياحة بحسبان أنَّها تؤثر وتتأثر ببقية أنواع السياحة.
جريمة السكن في دار أو شقة عائدة للدولة دون إذن أو عقد-دراسة مقارنة
Authors: أ.د إسماعيل نعمة عبود  , المعموري مصطفى علي حمد
Published: March 2024

تُعد جريمة السكن في دار أو شقة دون إذن أو عقد المملوكة للدولة من الجرائم المهمّة  و التي نظّمها المشرّع العراقي  في القرار التشريعي لمجلس قيادة الثورة المنحل رقم 36لسنة 1994وقد جاء المشرّع بعقوبة لهذه الجريمة تتناسب في الوقت الذي جاء بالتشريع ,إلا أنّ هذه الجريمة بدأت بالانتشار بعد  2003وما تشكله الدور والشقق العائدة للدولة من أهمية ,الا أنّ التجاوز عليها بالسكن من قبل المواطنين يعرقل عمل بعض الدوائر وهذا بدوره يؤثر على عمل المرافق العامة من تقديم الخدمات بانتظام, ولهذه الجريمة ثلاثة أركان هي الركن المادي الذي يتمثل بفعل السكن من خلال الانتفاع في دور أو الشقق العائدة للدولة دون موافقات أصولية  , أمّا الركن الثاني فهو الركن المحل وهو الدور والشقق العائدة للدولة, أمّا الركن الثالث والأخير هو الركن المعنوي, والمشرّع في هذه الجريمة طلب القصد الجرمي العام ,وقد قسّمنا البحث  على ثلاثة مباحث ,الأول ماهية جريمة السكن وسنتناول في المبحث الثاني أركان الجريمة ,ونخصّص في المبحث الثالث عقوبة جريمة السكن في دار أو شقة دون إذن  أو عقد.
التوجهات القانونية لحظر الحجاب في دول الإتحاد الأوروبي ـ دراسة دولية مقارنة ـ
Authors: م.د حسين محمد صادق موسى
Published: March 2024

إنَّ منعَ الحجابِ من قبلِ السلطات ليس بأمرٍ جديدٍ، لكنَّه جديدٌ نسبياً في الدول الأوروبية، والبداية كانت في فرنسا لعام 2004م، عندماحظرت الحجاب في مدارسها، وتبعتها دول أوروبية عدّة، وتفاوتت أشكال الحظر لتشمل البرقع والنقاب والبوركيني، ضمن النطاق الوطني للدولة أو النطاق المحلي للبلدية، وتضمّنت هذه القوانين عقوبات تشمل غرامات قد تصل للسجن.

  إما المحاكم الأوروبية، فقد كانت موقف بعضها مساندة للحظر، وأخرى مناهضة لها، وأبرزها قراري محكمة العدل الأوروبية لعام 2017م، وعام2021م، فأعطيا للشركات وأرباب العمل صلاحية منع توظيف المحجبات.

ولهذا الحظر أسباب متنوعة ظاهرية، وأخرى خفية، قد تعكس بعضها قناعات مسبقة متجذرة تاريخياً، وهذا ما أدى إلى آثار كثيرة على الرأي العام الأوروبي، وآثار اجتماعية وأمنية واقتصادية، فأثرت بشكلٍ كبيرٍ على فرص عمل المحجبات، واندماج المسلمين وفق دراسات موثّقة.
تجريمُ التنمرِ الالكترونيّ
Authors: م. د رقية فالح حسين
Published: March 2024

التنمر الالكتروني ظاهرة سلبية متنامية حديثة على مجتمعاتنا العربية، ظهرت تزامناً مع استعمال التكنلوجيا الحديثة، وباستعمال الشبكات المعلوماتية في التواصل الاجتماعي، إذ توالت على استعمالاتها اشكاليات قانونية وأهمها عدم خضوعها لهيئة أو منظمة حكومية رقابية، مما أدى إلى استغلالها بهدف إيذاء الغير بطريقة متعمدة وعدوانية، عن طريق نشر أو مشاركة محتوى أو صورة أو فيديو لشخص ما دون رضاه أو التلاعب بالصور والفيديوهات للتشهير أو التقليل من شأن الآخر أو احباطه أو ازعاجه، ليظهر بمظهر سيء أمام الآخرين، مما يتطلب من المُشرِّع العراقي التدخل تشريعياً بقانون خاص أو لتعديل قانون العقوبات لتجريم هذه الظاهرة كما فعل المُشرِّع المصري بقانون رقم (189) لسنة 2020 المعدل لقانون العقوبات المصري رقم (58) لسنة 1937.
O ensino dos conceitos iniciais de geometria analítica por meio do jogo batalha naval
Authors: MACHADO LOPES NETTO FRANCIELE
Published: March 2024

O artigo apresenta discussões sobre a aplicação do Jogo Batalha Naval como recurso didático para a introdução ao conteúdo de geometria analítica numa turma de terceiro ano regular do Ensino Médio da rede estadual, no município de Serra/ ES. As atividades propostas envolveram a ludicidade, priorizando a participação do aluno, a aprendizagem em grupo e seu protagonismo na construção do conhecimento. Para facilitar o entendimento dos alunos, tendo em vista as dificuldades encontradas pelos estudantes na assimilação de geometria analítica, foi estruturado um plano de aula direcionado a introdução dos conceitos iniciais com o uso do jogo Batalha Naval e atividade com questões associadas à ocorrência da prática executada em sala de caráter qualitativo. O plano foi desenvolvido em cinco aulas, os discentes participaram do desenvolvimento de forma relevante e as dificuldades encontradas durante às aulas foram sanadas com o auxílio de colegas e a mediação do professor. Ao final da aplicação constatamos a satisfação dos alunos à compreensão do assunto, criação de estratégias e raciocínio lógico. Ressaltando a importância da inserção de recurso didático para o ensino de geometria analítica, processo indutor de interesse e motivação, possibilitando aos discentes a autonomia na construção do seu conhecimento.
Benefícios do uso do ácido tranexâmico na hemorragia subaracnóidea aneurismática: revisão integrativa
Authors: Almeida Bruna , Souza Lima Daniel
Published: March 2024

A hemorragia subaracnóidea (HSA), categorizada como acidente vascular encefálico hemorrágico (AVEh), é considerada uma emergência neurológica devido ao seu potencial de morbimortalidade, já que constitui aproximadamente 3% dos eventos encefálicos hemorrágicos e tem como principal etiologia a ruptura aneurismática. Trata-se de uma revisão integrativa da literatura acerca do uso do ácido tranexâmico no contexto da hemorragia subaracnóidea. Para tanto, a busca dos artigos científicos utilizou-se das seguintes bases de dados: LILACS (Literatura Latino-Americana e do Caribe em Ciências da Saúde) e MEDLINE (Medical Literature Analysis and Retrievel Sistem Online), via Biblioteca Virtual em Saúde do Ministério da Saúde. O total foi 156 artigos científicos que correspondiam ao tema. Todavia, 7 foram duplicados. Para a fase de triagem, 144 (92%) trabalhos apresentavam aspectos gerais à temática e, portanto, aplicou-se o filtro de pesquisa com os critérios de inclusão desta revisão. Assim, reduzida para quantia de 38 (24,3%) artigos potencialmente elegíveis. Após leitura de título e resumo, 8 artigos foram selecionados para revisão completa e 1 trabalho foi excluído, resultando na amostra final desta revisão em 7 (4,4%) artigos. Percebe-se a heterogeneidade de resultados em relação a mortalidade e prognóstico neurológico ao longo de 6 meses, contudo, a taxa de ressangramento foi notadamente menor nos pacientes que utilizaram o ácido tranexâmico, principalmente quando o uso foi realizado em tempo menor a 72 horas.
Levantamento dos cuidados ao recém-nascido sob terapia intravenosa periférica para auxílio no diagnóstico para a construção do software-protótipo como estratégia de avaliação
Authors: Da Silva Cristiana Fialho Braz , Santiago Luiz Carlos
Published: March 2024

A presente pesquisa é um recorte da tese de doutoramento, concluída, sobre o diagnóstico para a proposta de construção um Software-Protótipo como Estratégia de avaliação do cuidado ao recém-nascido (RN) sob terapia intravenosa periférica. Portanto, este estudo tem como objetivo customizar os cuidados apontado pelos profissionais de enfermagem a partir de suas competências da prática profissional na terapia intravenosa periférica no RN, que será utilizado como base na construção futura de um software-protótipo que pretende nortear o cuidado ao RN com o cateter intravenoso periférico, para auxílio a esse profissional em sua decisão clínica.
Efecto de la contaminación atmosférica en los polinizadores del corredor industrial Guanajuato
Authors: Quintana Rodríguez Elizabeth , Rocha Vallejo Ana Rosa , Esparza Claudio José de Jes´ús , Hernández Cumplido Jonattan , Orona Tamayo Domancar
Published: March 2024

In recent years, due to industrial activity, there has been an increase in pollutants, particularly ozone O3. The industrial corridor of the state of Guanajuato is not the exception, especially due to the various industries established in this corridor that covers the municipalities of Celaya, Salamanca, Irapuato, Silao and Leon. In the same way, this area is characterized by its agricultural activity with important crops, among which are those that need insects and animals for their pollination. The pollutants have shown negative effects on the emission of volatile organic compounds emitted by the flowers and, which fulfil pollinator attraction functions. In this review, we analyse the main pollutants and their negative effects on the pollination service performed by pollinators. This information points to the urgent need to consider air pollution as a negative factor in pollinator-mediated pollination service.