bluuebunny/crossref_metadata_2025 huggingface dataset:
SÍNTESE DAS ATIVIDADES INSETICIDAS DO MONOTERPENO TIMOL SOBRE O Aedes aegypti
Authors: Ferreira da Silva Neto Irineu , Taveira dos Santos Ítalo , Vidal Barbosa Flávia Eduarda , Relison Tintino Saulo
Published: February 2025

Objetivou-se fazer um levamento na literatura científica sobre as propriedades inseticidas do monoterpeno timol sobre o Aedes aegypti. Trata-se de uma revisão de literatura de caráter descritivo e abordagem qualitativa. A busca se deu por meio da base de dados eletrônica National Library of Medicine (PubMed), utilizando os Medical Subject Headings (MeSH): “Thymol” e “Aedes aegypti” combinados pelo operador booleano AND. Os critérios de seleção estabelecidos foram: artigos datados entre janeiro de 2018 a maio de 2023, publicados no idioma inglês, com caráter descritivo, exploratório ou experimental que apresentassem os descritores específicos. Estudos que não estavam dentro do período delimitado, linguagem selecionada, incompletos, revisões de literatura ou não eram publicações relevantes para a síntese desta pesquisa, foram excluídos. A partir da análise dos dados, evidenciou-se que, as principais atividades inseticidas do timol frente ao A. aegypti centra-se nas propriedades larvicidas, estando majoritariamente associada a inibição a atividade da enzima acetilcolinesterase. A presença de tal fitoquímico foi evidenciado em óleos essenciais de diversos vegetais que, quando associados a outros compostos, proporcionou uma sinergia, o que amplia a suas potencialidades promissoras. Ademais, observou-se que existe uma lacuna tratando-se de investigá-lo de maneira isolada, a fim de conhecer suas reais atividades, sendo a principal limitação evidenciada pela pesquisa, o que fomenta a realização de novos estudos que possam comprovar o uso seguro do composto no controle do A. aegypti, bem como os mecanismos envolvidos na sua ação.
Tip-enhanced photoluminescence imaging of porphyrin tapes: exploring the nonlocality of molecular orbitals
Authors: Tomoshige Yoshitsugu , Tamura Mamoru , Ishihara Hajime
Published: February 2025

We have developed a theoretical framework for evaluating tip-enhanced photoluminescence (TEPL) of single molecules based on the nonlocal response theory. This framework self-consistently solves molecular polarization and electric field using a Green’s function accounting for arbitrary nanostructure geometries. Focusing on porphyrin tape molecules (two, four, and six units), our study reveals two-lobe TEPL images, where lobe separation increases with molecular size, deviating from point dipole approximations. Furthermore, TEPL images of optically forbidden transitions reflect the spatial structure of wavefunction and polarization. These calculations, clarifying mechanisms underlying experimental observations, advance understanding of nanoscale light–matter interactions and guide molecule-based photonic device design.
Political Polarization and Restoration of Representative Democracy
Authors:   Korean Constitutional Law Asscciation, Chong Sangwoo
Published: February 2025

This study is to examine the political polarization problems raised in Korea and to explore ways to improve the representative democracy system. The causes of polarization in Korea can be analyzed in various ways, and as the historical origin, ideological confrontation and regionalism, the form of government that has been operated under the so-called presidential system, the winner-takes-all political system, and social inequality intensified after neoliberalism. In order to overcome political polarization in Korea, efforts have been made to have the general public participate in the nomination of candidates by political parties, improve the legislative process to strengthen the agreement between the ruling and opposition parties of the National Assembly, improve the election system for proportional representation, operate a public debate committee, and introduce a public recall, but the results are not satisfactory. In this study, in order to re-establish representative democracy, it was proposed that the representative agency operate the representative agency in a way that is proportional to the responsibilities of the people. The details are as follows. First, the divisional government can be rather activated depending on the election results. To this end, the dismissal of the Prime Minister and the State Council members of the National Assembly is activated. Second, the term of office of the National Assembly is shortened to two years, and instead, the authority of the National Assembly is strengthened. Third, it is necessary to boldly delete the transcendent position and authority of the presidency that originate from ‘the Yushin Constitution’.
Bhoj Patra – The Paramount Reason why Ved Vyas Wrote the Mahabharata at Badrinath
Authors: Bali Dr. Sharadendu
Published: February 2025

Before the invention and prevalent use of paper, writing was an arduous process, accessible to only a few, and to those few also, it was time-consuming and onerous. Hence, availability of writing material was of paramount importance for authors and playrights, such as Kalidas and Charak. Bhoj-patra, the bark derived from the Himalayan Birch tree, is a suitable writing material, but available only at great heights in the Himalayas. It is obvious, that to write huge fables and scriptures, the Bhoj-patra was the most suitable material in ancient times. Hence, to pen down the voluminous Mahabharata epic, easy access to Bhoj-patra was a prerequisite, and must have formed an important reason for Sage Ved Vyas to put down his thoughts into words in the high Himalayas near Badrinath.
Identifikasi Kelainan Gen Protein Pita 3 pada Membran Sel Darah Merah Penderita Talasemia Î²
Authors: Dewajanti Anna Maria
Published: February 2025

Abstract : Thalassemia is a genetic disorder inherited as autosomal recessive. There is an imbalance Between the number of goblin chains Î± and b globin chains, so that there is an unpaired globin chains. Precipitation of unpaired globin chains in the membrane can lead to autooxidation the membrane so that it Can cause the cell membranes become rigid. Stability of red blood cell is very influenced by protein sitoskeleton function. Others the stability of red blood cells is also greatly influence by the band 3 protein, an integral transmembrane protein of red blood cells. Band 3 protein abnormalities may influence its function both as an ion exchange membraneÂ  and in maintaining the stability of red blood cells. Abnormal band 3 protein found in ovalositosis, a blood di sorder caused by the loss of nine amino acids of protein band 3 due to a deletion of codons 400-408 in exon 11 band 3 protein gene. The loss of nine amino acids in the protein band 3 ovalositosis causes red blood cell membranes become rigid, thus reducing the membrane deformability. The existence of rigidity accompanied by a decreased ability of red blood cell membrane deformability thalassemia-like red blood cell membrane ovalositosis, raises the idea that the destruction of red blood cell membrane protein also thalassemia is caused by abnormalities band 3 protein-coding genes. This study aims to identify any abnormalities of band 3 protein gene in patients with thalassemia. Genomic DNA obtained from blood of healthy individuals and patients with thalassemia. Genes will be examined later propagated by PCR and visualization techniques using 2% agarose gel electrophoresis. PCR results of band 3 protein gene in healthy individuals (normal) size of 175 Â± 25 bp, whereas in patients with thallasemia found two PCR product size 175 bp and 110 Â± 25 Â± 15 bp. Presence of PCR product size 110 Â± 15 bp showed a proteinÂ  band 3 gene defects in patients with thalassemia in the form of gene deletion by 65 Â± 10 bp. Genetic disorder of protein band 3 in thalassemia is not the same as genetic abnormalities in ovalositosis.Key words : thalassemia, protein band 3 gene, genetic disorders.
Pengetahuan, Sikap, dan Perilaku Ibu Rumah Tangga mengenai Konsumsi Yodium dan Faktor yang Berhubungan di Kelurahan Kelapa Dua Jakarta Barat
Authors: Susanto Djap Hadi , Suryana Melda , Wahyudin Asep , Septyani Sisca , . Yulisa , . Vera
Published: February 2025

AbstrakLatar belakang: Gamgguan akibat kekurangan Yodium (GAKY). Merupakan salah satu masalah nutrisi di Indonesia. Hasil survei konsumsi garam beryodium tingkat rumah tangga secara nasional pada tahun 2003 bara mencapai 73,24% rumah tangga yang mengkonsumsi garam dengan kandungan yodium >30 ppm. Di Jakarta saja, cakupan konsumsi garam yang mengandungcukup yodium hanya sebesar 68,70%. Tujuan penelitian ini adalah diketahuinya gambaran tingkat pengetahuan, sikap, dan perilaku ibu rumah tangga dan faktor-faktor yang berhubungan mengenai konsumsi yodium dalam rangka pencegahan penyakit Gangguan Akibat Kekurangan Yodium. Metode: Desain penelitian adalah deskriptif dengan pendekatan potong lintang (cross sectional). Populasi adalah ibu-ibu rumah tangga di Kelurahan Kelapa Dua, Kecamatan Kebon Jeruk, Jakarta Barat. Jumlah sampel sebesar 105 orang yang dipilih secara multistage simple random sampling. Data dikumpulkan melalui wawancara dan dengan bantuan kuesioner. Hasil: Sebaran menurut tingkat pengetahuan sebagian besar adalah rendah (41,0%), sikap baik (43,8%) dan sebagian besar berperilaku kurang (42,9%). Didapatkan adanya hubungan yang bermakna antara tingkat pengetahuan, sikap, dan perilaku ibu terhadap usia ibu, tingkat pendidikan ibu, sumber informasi, dan aktivitas sosial ibu ibu. Sementara itu didapatkan tidak ada hubungan antara perkerjaan ibu dan pendapatan keluarga terhadap tingkat pengetahuan, sikap, dan perilaku ibu. Terdapat hubungan yang bermakna antara perilaku ibu dengan pengetahuan dan sikap perilaku ibu, serta antara sikap ibu terhadap tingkat pengetahuan ibu mengenai konsumsi yodium.Kata kunci : konsumsi yodium, pengetahuan, sikap, dan perilaku ibu rumah tangga
Pengaruh Kalsium dalam Makanan Terhadap Penurunan Tekanan Darah
Authors: Winaktu Gracia J.
Published: February 2025

Abstrackblood pressure is determined by cardiac output (cardiac output) and peripheral resistance. The relationship between inputs of calcium (Ca) with decreased blood pressure of essential hypertensive patientsâ€™ was first proposed b Â addison in 1924. Ca is a mineral that is essential for the human body. Calcium helps in activating enzymes that stimulate many essential chemical reaction in the body also plays a role in blood coagulation. Ca can only be absorbed by the intestine about 35%, due to relatively low degree of solubility. Approximately 90% of the input Ca in the diet excreted in the feces each day. Parathyroid Â hormone is released to maintain the concentration of Ca ions, will increase the influx of extracellular to intracelluler Ca ions, so that the intracellular Ca ion concentration is very high. The inputs of Ca hypertensive patients are lower than normal people. This means that the lack of input of Ca in the diet will lead to increased blood pressure.Key words : Calcium, hypertensive essential, parathyroid hormone.
Nilai Diagnosis N-Terminal Prohormone of Brain Natriuretic Peptide untuk Mendeteksi Gagal Jantung Kronik Diastolik pada Pasien Hemodialistis Rutin
Authors: Silalahi Todung Donald Aposan
Published: February 2025

Abstrak Gagal jantung merupakan masalah utama kesehatan masyarakat dunia dan menjadi faktor penyebab utama mordibitas dan mortalitas. Di Amerika lima juta penduduk terdiagonis gagal jantung kongestif dan terdapat 500.000 kasus baru tiap tahun dimana sekitar 40-60% menderita gagal jantung diastolik. Gagal jantung dibedakan menjadi 2 bagian yaitu gagal jantung sistolik lebih baik daripada disfungsi sistolik. Pada tahun 2001, European Society of Cardiology, mengeluarkan suatu algoritma untuk gagal jantung dan disfungsi ventrikel kiri, di mana N-terminal Prohormone of Brain Natriuretic Peptide ( NT-proBNP) merupakan salah satu metode pemeriksaan yang rutin untuk mendiagnosis gagal jantung. Di dalam tubuh, sekresi NT- proBNP sama banyaknya dengan sekresi BNP, sehingga dapat digunakan untuk petanda gagal jantung.Kata kunci: NT-proBNP, gagal jantung diastolik, hemodialisis
Anestesi Regional Intravena(Bier's Block)
Authors: Sulistiono Paulus
Published: February 2025

Abstrak Anesti regional intravena merupakan teknik anestesi regional yang ditujukan untuk operasi pada daerah ekstremitas tubuh. Teknik ini bekerja dengan prinsip memblok darah yang menuju ekstremitas dengan menggunakan tourniquet kemudian menyuntingkan anestasi lokal pada daerah tersebut untuk menginduksi anestesi. Pada pemakaiannya sudah terdapat beberapa modifikasi untuk meminilasi beberapa keterbatasan yang ditimbulkan oleh teknik ini. Di susunlah artikel ini yang membahas mengenai aplikasi klinis, kontraindikasi, prosedur pelaksanaan, anestesi lokal pilihan, komplikasi, dan adjuvan untuk mengatasi komplikasi dari anestesi regional intravena.Kata kunci: anestesi regional intravena, bierâ€™s block, nyeri tourniquet
Bilirubinometri Transkutaneus
Authors: Ruslie Riska Habriel , . Darmadi
Published: February 2025

abstrakjaundice atau hiperbilirubinemia sering terjadi pada neonatus. walaupun kebanyakan Â kasus tidak berbahaya, hiperbilirubinemia berat dapat menyebabkan kernikterus, yang dapat di cegah jika hiperbilirubinemia diindefikasikan sejak dini dan di tatalaksanakan dengan tepat. Disusun lah artikel ini yang membahas mengenai jaundice pada neonatus dan penggunaan Â bilirubinometri transkutaneus untuk deteksi neonatus yang berisiko hiperbilirubinemia berat. pemeriksa bilirubin transkutaneus (TcB) adalah pilihan untuk skrining neonatus jika ada risiko secara kelinis terjadi hiperbilirubinemia.kata kunci: bilirubinometri transkutaneus, neonatus, skrining
Nilai Diagnosis N-Terminal Prohormone Brain Natriuretic Peptide untuk Mendeteksi Gagal Jantung Kronik Diastolik pada Pasien Hemodialistis Rutin di Unit Hemodialistis RSUPN Dr. Cipto Mangunkusumo Jakarta
Authors: Silalahi Todung , Panggabean Marulam M. , Alwi Idrus , I Suzanna , . Dharmeizar
Published: February 2025

AbstractÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â  Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Aims: to compare Ntpro-BNP levels in chronic kidney failure undergoing routine hemodialysis without diastolik heart failure,with chornic kidney failure patients undergoing routine hemodialysis with chronic diastolik heart failureÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â  Methods and results: 60 chronic kindey disease in Cipto Mangunkusumo Hospital Hemodialysis unit were undergoing routine hemodialysis between june 2007 to October 2007 were chosen for the research. Their left ventricular functions, both sys tolic dan diastolik, were measured using echocardiography. Their mean NT pro-BNP values were also recorded. Mean of NT pro â€“BNP in normal LV fucition without diastolik dysfuncition in 41 pepople is 11.600,2 (sta ndard deviation 10.356,1),with minimum value of 61o,8 pg/ml and maximal vaule of 35,000 pg/ml, NT pro â€“BNP vaue of19.170 pg/dl as diagnostic test for diastolik heart failure thus shows that it haws 84% sensitivity and 80% specificity value.Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â  Conclusion: NT pro-BNP can be used to datect chronic diastolikÂ  heart fa in patient undergoing routine hemodialysis keyÂ  Â words: Echocardiography, NT pro-BNP, left ventricular funcition, chronic kidney failure, chronicÂ  diastolik heart failureÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â  Â
Formulasi salep sari batang daun talas (Colocasia esculenta L. ) schoot pada penyembuhan luka sayat pada tikus putih jantan (Rattus norvegicus)
Authors: Ardiani Rani , Shufyani Fahma , Siregar Syati Manaharawan , Silalahi Ali Affan
Published: February 2025

Pendahuluan: Talas memiliki beberapa senyawa yang dapat mempercepat penyembuhan luka, seperti flovanoid, fenol, dan saponin. Senyawa ini bertindak sebagai antibiotik alami, membersihkan luka dengan sifat antibakterial dan antifungalnya. Oleh karena itu, tanaman ini dapat membantu proses penyembuhan luka. Tanin, di sisi lain, memiliki kemampuan untuk menciutkan pembuluh darah dan mengurangi pendarahan di daerah luka, mengurangi infeksi dan membantu penyembuhan luka selama fase inflamasi. Salah satu faktor penyembuhan luka, vitamin C membantu memperkuat dinding pembuluh darah, terutama di daerah yang luka, untuk menjaga suplai darah tetap ada di sana dan membantu mempercepat sistensis kolagen selama proses penyembuhan luka. Lektin, zat yang dapat mempercepat penutupan luka dengan membantu regenerasi sel lebih baik. Tumbuhan araceae memiliki banyak manfaat bagi masyarakat, seperti dapat digunakan sebagai sumber makanan dengan mengambil umbinya, atau dapat digunakan sebagai tanaman hias yang menghiasi pekarangan. Talas juga digunakan sebagai obat-obatan di dalam dan di luar tubuh. Hampir semua organ tumbuhan talas diolah menjadi obat-obatan, dan organ umbi, kulit batang, dan akarnya ditumbuk dan kemudian diterapkan pada kulit untuk menyembuhkan luka atau memar. Tujuan: Penelitian ini bertujuan untuk mengetahui efek penyembuhan luka sayat dari sari batang daun talas (Colocasia esculenta L) schoot pada tikus jantan (rattus nervegicus). Metode: Penelitian ini menggunakan metode eksperimental, yang meliputi pengambilan sampel, pembuatan sari batang daun talas dengan konsentrasi 2%, 4%, 6%, uji evaluasi salep dan uji aktivitas penyembuhan luka sayat terhadap tikus putih yang dikelompokan menjadi 5 kelompok dengan masing-masing kelompok terdiri dari 3 tikus. Analisis statistik meliputi uji one way ANOVA untuk melihat ada tidaknya perbedaan signifikan antar kosentrasi dengan penyembuhan luka sayat tikus Jantan putih. Hasil: Penelitian yang dilakukan menunjukan bahwa F1 (kosentrasi 2 %) dapat menyembuhkan tikus pada hari ke- 10 F2 (kosentrasi 4%) kesembuhan tikus pada hari ke-8, F3 (kosentrasi 6 %) kesembuhan luka sayat pada hari ke-7, kontrol positif (Betadine salep) kesembuhan tikus semua dihari ke-7. Kesimpulan: Sari batang daun talas (Colocasia esculenta L) Schoot dapat diformulasikan dalam sediaan salep untuk penyembuhan luka sayat tikus putih jantan (Rattus norvegicus), dengan kosentrasi yang paling efektif adalah konsentrasi 6% karena mampu menyembuhkan luka sayat yang paling cepat diantara konsentrasi yang lainnya.
Formulation of flower ethanol extract lip cream combrang (Etlingera elatior (Jack) R. M. Sm.) and roselle flower (Hibiscus sabdariffa L.) as a natural dyeing substance
Authors: Rumanti Ruth Mayana , Sari Rika Puspita
Published: February 2025

Introduction: The kecombrang flower and roselle flower are known as sources of natural antioxidants and have the potential to be used as natural dyes in lip cream products. Both types of flowers contain compounds such as tannins, flavonoids, and saponins. The aims of study to analyze the effect of varying concentrations of ethanol extract from the kecombrang flower (Etlingera elatior (Jack) R. M. Sm.) and the roselle flower (Hibiscus sabdariffa L.) on the color of lip cream formulations. The method of research was conducted through laboratory experiments that included sampling, extract preparation, product formulation, physical quality evaluation, and panelist preference testing. Data were analyzed descriptively by calculating the percentage of preference levels and presented in the form of tables and graphs. The results show that the preparation has a semi-solid texture, with colors ranging from light pink to dark pink in certain combinations, and a purplish pink for the 10% roselle extract formulation. The pH of the preparation is in the range of 5.1-5.4, without coarse grains, good spreadability, an average spread distance of 5.5 cm, an average adhesion time of 12.73 seconds, and no irritation. The cycling test indicates color instability, changing from light pink to dark brownish purple. Based on the hedonic test, formulation F5 has the highest preference level, which is 88.33%. The conclusion of this study is that the ethanol extract of kecombrang and rosella flowers produces a light pink lip cream that is suitable for formulation in lip cream preparations. The higher the concentration of the extract used, the darker the pink color produced, with a texture that tends to be more liquid and a decreasing pH.
PERFIL DE INCIDÊNCIA DE INFARTO AGUDO DO MIOCÁRDIO E ACIDENTE VASCULAR CEREBRAL EM ADULTOS JOVENS: ANÁLISE DE UMA DÉCADA
Authors: Reis Lima Andressa Bianca , Cavalcante Carvalho Clara Vitória , Costa Martins Luiz Guilherme , Guareschi Dafne Ercole , Sensi Santhiago Gabriela , Garcia Kristen , Soares Marques Guimarães Eduardo , Saucedo Lage Eduardo , Roberto Anderson Claudio , Lima Pinho Marcos , DE ASSIS MOREIRA MURILO JOSE , Morais Thaís Pâmela , FONSECA PHILIPE DE CARVALHO , Cardoso Renato de Mattos , Cardoso Arthur Barbosa , Santiago Bryan Luidi de Assis , Mazarão Iana Caroline Nadolny
Published: February 2025

O Acidente Vascular Cerebral (AVC) é uma condição neurológica causada por isquemia e infarto cerebral devido à obstrução de uma artéria cerebral. Existem dois tipos principais de AVC: o isquêmico, por obstrução do vaso, e o hemorrágico, por hemorragias cerebrais. Além disso, as doenças cardiovasculares (DCV), como o Infarto Agudo do Miocárdio (IAM), são uma das principais causas de morbidade e mortalidade global, resultando da morte de células cardíacas devido à obstrução do fluxo sanguíneo coronariano. Este estudo analisou internações hospitalares de jovens adultos no Brasil por AVC e IAM entre 2013 e 2023, utilizando dados do Sistema Único de Saúde (DATASUS) e do Sistema de Morbidade Hospitalar (SIH). A análise foi ecológica, descritiva e retrospectiva, considerando variáveis como ano, região, faixa etária, cor/raça, sexo, tempo de internação e óbitos. Os dados foram coletados e analisados em julho de 2024, com base em artigos científicos recentes. Entre 2013 e 2023, o Brasil registrou 115.795 internações por IAM e AVC em jovens adultos. O ano de 2023 teve o maior número de casos (11,31%), enquanto 2013 teve o menor (7,5%). A região Sudeste concentrou a maioria dos casos (42,74%), com São Paulo liderando. A faixa etária mais afetada foi de 30 a 39 anos (75,67%), com predominância do sexo masculino (56,16%) e cor parda (38,96%). A maioria dos atendimentos foi de urgência (94,92%), com uma média de permanência hospitalar de 6,7 dias. Os óbitos foram mais frequentes entre indivíduos de 30 a 39 anos (76,77%).Nota-se um aumento preocupante nos casos de IAM e AVC entre jovens, destacando a necessidade urgente de estratégias de prevenção, diagnóstico precoce e tratamento adequado. Políticas públicas devem focar na promoção de estilos de vida saudáveis e no monitoramento precoce dos fatores de risco.
Transtorno de Estresse Pós-Traumático: Quando Suspeitar e Como Diagnosticar?
Authors: BARROS DE MACEDO RYAN RAFAEL , DA SILVA SANTOS FLÁVIO JÚNIOR , TENÓRIO ZAIDAN NATHÁLIA RÉGIA , ROQUE DA SILVA CATARINE , DANTAS DA COSTA ISABEL BEATRIZ , TEIXEIRA PEREIRA JÉSSICA KÉSSYLA , STONE DE ANDRADE ANA LAURA , SALES DE BARROS LUANA , SICHIERI GESSOLO JAILSON PAVIN , GONÇALVES DE FREITAS SARAH VIVIAN , PINTO GOMES NELSON , FERREIRA ALESSA MARCELA
Published: February 2025

RESUMO
O Transtorno de Estresse Pós-Traumático (TEPT) é um transtorno psiquiátrico que ocorre após a exposição a eventos traumáticos, afetando negativamente o funcionamento psicossocial dos indivíduos. Esta revisão aborda as mudanças nos critérios diagnósticos ao longo das versões do DSM e da CID, destacando as diferenças nas abordagens e implicações clínicas. No DSM-5, a ampliação do espectro sintomático resultou em um aumento na heterogeneidade do transtorno, enquanto a CID-11 simplificou os critérios, o que reduziu a prevalência diagnóstica. A revisão aponta também a necessidade de uma melhor compreensão dos estressores psicossociais e do TEPT complexo, além de ressaltar a importância do diagnóstico precoce e das intervenções direcionadas para um manejo eficaz do transtorno.
Candidíase Vulvovaginal Recorrente
Authors: BARROS DE MACEDO RYAN RAFAEL , ROQUE DA SILVA CATARINE , DANTAS DA COSTA ISABEL BEATRIZ , SALES DE BARROS LUANA , VILA NOVA DOS SANTOS LETICIA FERNANDA , RÊGO DE MORAES MARIANA , SOUZA MARQUES VERÔNICA GABRIELA , TORRES MARCONDES MARCOS , SILVA SANTIAGO VÍVIAN , YUJRA QUELALI SONIA LORENA , FERREIRA DOS SANTOS JÚLIA , DE OLIVEIRA MOREIRA GABRIELLE
Published: February 2025

RESUMO
A candidíase vulvovaginal recorrente (CVVR) é uma condição clínica complexa, caracterizada por múltiplos episódios sintomáticos anuais, com impacto significativo na qualidade de vida das pacientes. Este artigo analisa as estratégias terapêuticas e desafios no manejo da CVVR, destacando a resistência fúngica crescente, a diversidade de espécies de Candida e as limitações dos regimes convencionais baseados em azóis. Diretrizes internacionais recomendam terapia de indução e manutenção com fluconazol, porém até 50% das pacientes apresentam recorrência após a suspensão do tratamento, especialmente em casos envolvendo espécies não albicans (NAC) ou cepas resistentes. Alternativas como ácido bórico, nistatina e anfotericina B demonstraram eficácia em cenários específicos, embora com restrições de segurança e acesso. Inovações farmacológicas, como o oteseconazol e o ibrexafungerp, emergem como opções promissoras, com eficácia comprovada em ensaios clínicos contra cepas resistentes e NAC, enquanto a vacina NDV-3A sinaliza avanços na imunomodulação. O manejo em populações especiais, como diabéticas e mulheres vivendo com HIV, exige abordagens individualizadas, incluindo controle glicêmico rigoroso e evitando interações medicamentosas. A formação de biofilmes e a escassez de antifúngicos eficazes contra NAC destacam a necessidade de pesquisas futuras em terapias combinadas e disruptores de resistência. Conclui-se que a personalização do tratamento, aliada a investimentos em novas moléculas e estratégias preventivas, é essencial para reduzir a recorrência e melhorar os desfechos clínicos.
ANALISE DOS NASCIMENTOS COM SÍNDROME DE DOWN NO BRASIL
Authors: Leal Iago Brenner Farias , Andrade Izabelly Ferreira de , Lima João Pedro Leal de , Farias Beatriz Cardoso , Silva Palloma de Araújo , Brandão Isabella Rocha Cavalcanti , Silva Maria Úrsula Félix da , Sales Arthur Sarmento , Jacó Ana Izabel Lopes Rodrigues , Lopes Luciana Clédina Bezerra , Dantas Hellen Kerlly Morais , Oliveira Marielle Ferreira de , Alves Isac Campos , Costa Carlos Felipe Maciel , Nóbrega Renata Medeiros da , Diniz Nacssária Régia Cavalcante , Neves Maria Eduarda Pires de Souza , Filho Paulo Vieira de Sousa
Published: February 2025

Introdução: A Síndrome de Down é uma condição genética causada pela trissomia do cromossomo 21, caracterizada por traços físicos típicos, hipotonia muscular e deficiência intelectual. A síndrome é associada a um maior risco de doenças crônicas, tornando essencial o diagnóstico precoce e a oferta de estímulos adequados. No Brasil, o registro de nascimentos com Síndrome de Down é realizado pelo Sistema de Informações sobre Nascidos Vivos. Objetivo: Analisar os dados do SINASC entre 2015 e 2019, identificando tendências e fatores associados à incidência da Síndrome de Down. Método: Estudo documental descritivo com abordagem quantitativa, baseado na análise de 5.512 nascimentos com Síndrome de Down registrados no Brasil entre 2015 e 2019. Foram investigadas características maternas e condições do nascimento a partir das informações fornecidas pelos serviços de saúde. Resultados: Os dados epidemiológicos indicaram uma prevalência de Síndrome de Down três vezes menor do que o esperado segundo a literatura. A distribuição regional revelou diferenças significativas, com maior prevalência no Sul e Sudeste, possivelmente associada a fatores sociodemográficos, como o adiamento da maternidade em regiões mais desenvolvidas. Os achados também corroboram a relação entre idade materna avançada e o aumento do risco para a síndrome. Conclusão: Os resultados reforçam a necessidade de aprimorar a notificação, o diagnóstico e o acompanhamento da Síndrome de Down no Brasil. Com foco na capacitação profissional, melhoria do pré-natal e acesso equitativo à saúde, especialmente em regiões menos desenvolvidas.
MANEJO DA SÍNDROME DE RETT EM CRISES PSIQUIÁTRICAS E EMERGÊNCIAS: DESAFIOS NO ATENDIMENTO MULTIDISCIPLINAR
Authors: Rodrigues de Carvalho Daniella , Milani Vanessa Emanuelle dos Reis , Inoue Sophye Bianco de Soto , Costa Isabela Barbosa Tedesco da , Gadbem Rafael Galvão , Nascimento Gabriel Luz Fonseca Bellott , Ribeiro Fernanda Cristina Cardozo , Morita Heloisa Mariko , Silva Maria Eduarda Dias da , Neto Jorge Ferreira de Medeiros , Suleiman Yasmin Mamede , Silva Isabella Marques da
Published: February 2025

Este artigo revisa a literatura científica sobre o manejo da Síndrome de Rett em crises psiquiátricas e emergências médicas, com foco nos desafios enfrentados durante o atendimento multidisciplinar. A pesquisa, realizada nas bases de dados PubMed, Scopus e Web of Science, utilizando os termos "Síndrome de Rett, Crises psiquiátricas, Emergências médicas, Atendimento multidisciplinar", revela que pacientes com Síndrome de Rett frequentemente desenvolvem sintomas psiquiátricos, como crises de ansiedade, distúrbios comportamentais, depressão e autolesões. Esses sintomas podem ser tanto preexistentes quanto exacerbados por situações de emergência, dificultando o tratamento imediato e a recuperação pós-tratamento. A abordagem terapêutica para esses pacientes exige uma estratégia integrada e coordenada, envolvendo equipes multidisciplinares de psiquiatras, neurologistas, psicólogos, terapeutas ocupacionais e profissionais de emergência. O manejo das crises psiquiátricas deve ser adaptado para considerar o impacto emocional e as condições psiquiátricas, com ênfase na minimização do sofrimento emocional e no tratamento das comorbidades psiquiátricas. Intervenções como o suporte psicológico contínuo, o uso de medicações psicotrópicas e a monitorização constante do estado mental são fundamentais para garantir uma recuperação bem-sucedida.
IMPACTO DA MONITORIZAÇÃO INTRACRANIANA EM PACIENTES COM TRAUMA CRANIOENCEFÁLICO
Authors: Andrade Bianda de Figueiredo Moreira , Guimarães Pedro Figueiredo , Mansur' Guilherme , Souza Lucas Silva , Carvalho Ramos Dutra Sâmela , Bastos Francisco Antônio Dias de Azeredo , Bastos Fernando Dias de Azeredo , Lopes Dionisio de Figueiredo
Published: February 2025

Este artigo revisa a literatura atual sobre a monitorização da pressão intracraniana (PIC) em pacientes com traumatismo cranioencefálico (TCE) grave, destacando sua influência nos estágios clínicos. O TCE é uma das principais causas de morbimortalidade no mundo, e o monitoramento da PIC tem sido uma estratégia importante para prevenir lesões secundárias, especialmente a mortalidade em casos específicos. Estudos revisados ​​sugerem que o monitoramento pode ajudar na identificação precoce de complicações e na otimização de intervenções neurocirúrgicas, embora haja controvérsias sobre seu impacto na recuperação funcional e na qualidade de vida. Além disso, a variabilidade na adoção dessa prática entre diferentes centros hospitalares aponta para a necessidade de diretrizes mais padronizadas. A análise crítica das evidências mostra que, apesar de sua disponibilidade no manejo intensivo do TCE grave, ainda há incertezas quanto à real efetividade do PIC na melhoria dos resultados funcionais a longo prazo. Recomenda-se a realização de ensaios clínicos multicêntricos futuros para elucidar melhor seu papel na prática clínica.
VENTRICULOSTOMIA ENDOSCÓPICA DO TERCEIRO VENTRÍCULO NO MANEJO DA HIDROCEFALIA PEDIÁTRICA
Authors: Guimarães ´Pedro Figueiredo , Andrade Bianca de Figueiredo Moreira , Mansur Guilherme , Carvalho Ramos Dutra Sâmela , Sousa Lucas Silva , Bastos Francisco Antônio Dias de Azeredo , Bastos Fernando Dias de Azeredo , Lopes Dionísio de Figueiredo
Published: February 2025

O objetivo do artigo é avaliar os resultados clínicos e prognósticos da VETV  no manejo da hidrocefalia pediátrica, comparando sua eficácia e segurança com a derivação ventriculoperitoneal (DVP). O estudo também visa identificar os principais fatores prognósticos associados ao sucesso ou falha do procedimento e discutir o impacto da VETV   na qualidade de vida dos pacientes, além de destacar avanços tecnológicos recentes que podem influenciar os resultados cirúrgicos. Foi realizada uma revisão de literatura abrangente utilizando as bases de dados PubMed, LILACS e Scopus, relacionados a “Endoscopic Third Ventriculostomy”, “Hidrocefalia”, “Qualidade de Vida” e “Complicações Cirúrgicas”. Foram selecionados 10 artigos relevantes que abordam a eficácia, segurança, complicações e fatores prognósticos da VETV  . A VETV   mostrou-se uma alternativa eficaz à DVP, especialmente em pacientes com hidrocefalia obstrutiva. O sucesso do procedimento foi maior em crianças acima de um ano e naquelas com estenose do aqueduto de Sylvius. Fatores como idade inferior a um ano, hidrocefalia pós-hemorrágica e presença de septações ventriculares foram associados a maior risco de insuficiência precoce. As principais complicações relacionadas foram recidiva de hidrocefalia, infecção e fechamento prematuro do estoma. A VETV   é uma técnica segura e eficaz no manejo da hidrocefalia pediátrica, particularmente em crianças com hidrocefalia obstrutiva e idade superior a um ano. Apesar de sua eficácia ser influenciada por múltiplos fatores prognósticos, o procedimento apresenta vantagens significativas em relação ao DVP em termos de qualidade de vida e redução de complicações a longo prazo. Estudos futuros, especialmente de longo prazo, são necessários para definir critérios mais precisos de indicação e melhorar os resultados clínicos.
ABORDAGENS BASEADAS EM EVIDÊNCIAS PARA O DIAGNÓSTICO E MANEJO DA PNEUMONIA PEDIÁTRICA: UMA REVISÃO INTEGRATIVA
Authors: Queiroz Roger Antonio Morais , Freire Mayze Pereira Dal Col , Barbosa Edna Cláudia Mendes , Silva Thaylane Araújo e , Bressan Aline Alencar de Andrade , Lacerda Ludmila Melo , Souza Thais Mara Galdino de , Barros Rafaellen Milhomem , Teixeira Maria Eliza Alves , Pereira Karoline Alves
Published: February 2025

Introdução: A pneumonia pediátrica é uma das principais causas de morbidade e mortalidade infantil, especialmente em países de baixa e média renda. Apesar de avanços, desafios como diagnóstico diferencial, resistência antimicrobiana e fatores socioeconômicos limitam a efetividade de intervenções. Este estudo integra as evidências disponíveis sobre diagnóstico, manejo e prevenção da pneumonia em crianças.Objetivo: Reunir e avaliar criticamente evidências científicas sobre as melhores abordagens diagnósticas e terapêuticas na pneumonia pediátrica, destacando lacunas e avanços relevantes. Métodos: A revisão foi conduzida em bases de dados reconhecidas (PubMed, Scielo, LILACS, BVS e MEDLINE) e incluiu estudos publicados nos últimos dez anos em português, inglês e espanhol. Foram selecionados ensaios clínicos, revisões sistemáticas, metanálises e estudos observacionais envolvendo crianças de 0 a 18 anos. As evidências foram analisadas qualitativamente e organizadas por categorias temáticas. Resultados: Vacinas conjugadas contra Haemophilus influenzae tipo b e Streptococcus pneumoniae reduziram significativamente hospitalizações e óbitos por pneumonia pediátrica. Biomarcadores como PCR e procalcitonina melhoraram o diagnóstico diferencial, mas apresentam limitações em infecções mistas. Terapias de suporte, como oxigenoterapia de alto fluxo e CPAP, mostraram-se eficazes no manejo de casos graves. Discussão: A revisão destacou avanços nas intervenções clínicas e preventivas, mas apontou lacunas, como o impacto de sorotipos não vacinais e a necessidade de ferramentas diagnósticas mais acessíveis. Barreiras em populações vulneráveis limitam o alcance de estratégias baseadas em evidências. Conclusão: Estratégias integradas, como vacinação ampliada, diagnóstico aprimorado e manejo terapêutico eficaz, são essenciais para reduzir a carga global da pneumonia pediátrica, especialmente em contextos de desigualdade.
Palavras-chave: pneumonia pediátrica, vacinas conjugadas, biomarcadores, manejo terapêutico, saúde pública.
ANALISIS KETERAMPILAN BAHASA INDONESIA MELALUI AKTIVITAS PENDIDIKAN JASMANI
Authors: Julia Arpianti Nabira , Hanif Nugraha Rayhan , Catur Surya Mardhika , Raditya Arifin Farrel , R.J Tambunan Kevin , Mochamad Whilky Rizkyanfi
Published: February 2025

Penelitian ini bertujuan untuk menganalisis pengaruh aktivitas pendidikan jasmani terhadap keterampilan bahasa Indonesia siswa, dengan fokus pada keterampilan berbicara dan mendengarkan. Menggunakan pendekatan deskriptif kualitatif, data diperoleh melalui angket terbuka yang disebarkan kepada mahasiswa Pendidikan Jasmani Kesehatan dan Rekreasi (PJKR) di Universitas Pendidikan Indonesia. Hasil penelitian menunjukkan bahwa aktivitas jasmani dapat meningkatkan keterampilan berbicara dan mendengarkan siswa, memfasilitasi rasa percaya diri dalam komunikasi, dan memperluas wawasan mereka. Sebanyak 87,5% responden melaporkan peningkatan keterampilan berbicara, sementara 75% menyatakan bahwa aktivitas fisik membantu mereka menggunakan bahasa Indonesia dengan lebih lancar. Pembahasan penelitian menghubungkan temuan ini dengan teori pembelajaran kontekstual, yang menyatakan bahwa pembelajaran bahasa dapat terjadi lebih efektif dalam lingkungan yang interaktif dan kolaboratif. Penelitian ini menyarankan agar pendekatan serupa diterapkan di bidang lain serta mendorong penelitian lanjutan untuk mengeksplorasi dampak kegiatan pada keterampilan bahasa lainnya, seperti menulis dan membaca.
Kata kunci : Keterampilan bahasa Indonesia, Pendidikan Jasmani, Kualitatif, Berbicara, Mendengarkan
PENGARUH METODE LATIHAN EL RONDO DAN CIRCLE PASSING DRILL TERHADAP KETEPATAN PASSING DALAM PERMAINAN SEPAKBOLA SSB HARIMAU BEKONANG TAHUN 2024
Authors: Pipit Fitria Yulianto  , Dwi Gunadi  , Muh. Ikhwan Iskandar  , Ronny Suryo Narbito  , Eriek Satya Haprabu  , Rayudya Cella Aprilianto
Published: February 2025

Tujuan penelitian untuk mengetahui perbedaan pengaruh metode latihan el rondo dan circle passing drill terhadap ketepatan passing dalam permainan sepakbola pada atlet putra usia 15-17 Tahun SSB Harimau Bekonang Sukoharjo, dan jika ada perbedaan maka untuk mengetahui mana yang lebih baik antara metode latihan el rondo dan circle passing drill terhadap ketepatan passing dalam permainan sepakbola pada atlet putra usia 15-17 Tahun SSB Harimau Bekonang Sukoharjo. Sampel penelitian adalah Pada Atlet SSB Harimau Bekonang Sukoharjo dengan jumlah 30 siswa. Pengambilan sampel menggunakan teknik porpusive sampling. Variabel penelitian ini yaitu hasil ketepatan passing dengan latihan el rondo dan circle passing drill sebagai variabel bebas serta hasil ketepatan passing variabel terikat. Rancangan penelitian menggunakan pretest-posttest design. Tes untuk mengetahui ketepatan passing menggunakan tes ketepatan passing menggunakan petunjuk pelaksanaan tes dari Nur Hasan (2001: 157). Metode analisis data penelitian menggunakan rumus t-test yang diperhitungkan menggunakan rumus pendek. Hasil analisis data maka simpulan diperoleh: (1) Ada perbedaan pengaruh yang signifikan antara latihan el rondo dan circle passing drill terhadap ketepatan passing dalam permainan sepakbola pada atlet putra usia 15-17 Tahun SSB Harimau Bekonang Sukoharjo Tahun 2024. Hal ini dibuktikan dari hasil penghitungan tes akhir masing-masing kelompok yaitu thitung = 3.036 lebih kecil dari pada ttabel = 2,145 dengan taraf signifikasi 5%. (2) Latihan el rondo lebih baik pengaruhnya dari pada metode circle passing drill terhadap ketepatan passing dalam permainan sepakbola pada atlet putra usia 15-17 Tahun SSB Harimau Bekonang Sukoharjo Tahun 2024. Berdasarkan persentase peningkatan ketepatan passing dalam permainan sepak bola menunjukkan bahwa kelompok 1 (kelompok yang mendapat perlakuan dengan latihan el rondo) adalah 95.745% > kelompok 2 (kelompok yang mendapat latihan circle passing drill) adalah 58.929%.
Kata Kunci  : El Rondo, Circle Passing Drill, Ketepatan Passing
Initial growth response of twelve
Saccharum
Complex genotypes to inoculation using
Nitrospirillum viridazoti
Authors: Silva Alex Paulo Lemos da , Silva Luíz Felipe Coutinho da , Alves Bruno José Rodrigues , Reis Veronica Massena
Published: February 2025

Sugar and alcohol production in Brazil comes from planting hybrids from the crossing of species belonging to the Saccharum Complex. However, little is known about the growth response of these genera to inoculation using a diazotrophic bacteria Nitrospirillum viridazoti strain BR11145, currently recommended in Brazil as an inoculant for sugarcane growth promotion. This study aimed to evaluate the initial growth of 12 sugarcane genotypes inoculated or not with the strain BR11145. After 109 days, plant growth, biomass and macronutrient accumulation were evaluated. Fresh and dry mass at the end of the trial showed a positive response to inoculation for the genotypes US72-1319, CPDAU 849678, and NG77-122 of S. spontaneum and for Fiji 10 of Miscanthus. A negative response was observed for Q45416 of Saccharum sp. The growth of S. spontaneum US72-1319 is significantly improved by the inoculation with BR11145, which leads to a high accumulation of nutrients, especially N, standing out among the genotypes tested.
Automatic measurement of surface runoff at the plot scale
Authors: Rauber Lucas Raimundo , Reinert Dalvan José , Gubiani Paulo Ivonir , Nunes Kelvin Salbego , Mallman Micael Stolben
Published: February 2025

Although the hydrological importance of water infiltration into the soil and surface runoff is well known, manual measurement of these processes, especially at the plot and hillslope scales, is laborious and requires a trained team. This study aimed to develop prototypes with the tipping bucket principle for the automatic monitoring of surface runoff at a plot scale (14.5 × 3 m). In total, 18 prototypes were built and installed in an experiment with different soil covers. Aspects of the construction, calibration, operation and maintenance of the prototypes were reported in this study. Prototypes showed a satisfactory ability to monitor surface runoff with flow rates up to ~80 L min
-1
. The devices have an adjustable resolution of up to 5 L pulse
-1
, and they are inexpensive, easy to construct and simple to maintain. Although designed for a specific plot size (43.5 m
2
), the equipment can be adapted to smaller or larger plots by adjusting the volume of the tipping chambers. The proposed systems allow greater practicality in conducting experiments to monitor water loss through surface runoff at the plot scale and provide more detailed recordings of information.
Institutional mechanism for ensuring economic security of enterprises
Authors:   Poltava State Agrarian University, Mykolenko Inna
Published: February 2025

The article is devoted to ensuring enterprises’ economic security in the context of an unstable external environment. The purpose of the article is to develop an institutional mechanism for ensuring the economic security of enterprises. The study examines the key aspects of ensuring enterprises’ economic security under highly dynamic external changes. It is determined that economic security is a multifaceted system encompassing financial, informational, human resource, technological, legal, environmental, market, and investment components of enterprise operations. These components’ interaction and role in ensuring enterprises’ stability, competitiveness, and protection are analyzed. The study substantiates the importance of financial security as the foundation for sustainable enterprise development, which ensures the balance of income and expenses, effective capital management, and minimization of financial risks. The importance of information security is highlighted, focusing on protecting commercial information, monitoring cyber threats, and maintaining data confidentiality. The significance of human resource security is emphasized, including the development of human capital, enhancement of employee motivation, and minimization of internal conflicts. Technological security is analyzed as a factor ensuring the modernization of production processes, protection of intellectual property, and implementation of innovative technologies. Legal security is a tool for avoiding legal risks and ensuring compliance with legislative requirements. The essence of environmental security is revealed in transitioning to sustainable development, mainly through implementing energy-efficient solutions and reducing environmental impact. The article proposes an institutional mechanism for ensuring the economic security of enterprises, which is based on integrating and harmonizing regulatory, organizational, resource, and market components of institutional support. It is determined that the regulatory component ensures legal stability, the organizational component establishes effective management structures, the resource component optimizes resource management, and the market component enhances competitiveness and adaptation to market changes. The comprehensive approach involves the interaction of institutional components with the key aspects of economic security: financial, informational, environmental, human resource, legal, technological, investment, and market components. The proposed mechanism enables enterprises to minimize risks, adapt to external challenges, leverage new growth opportunities, and ensure sustainable development in the long term.

Keywords: economic security of enterprises, mechanism for ensuring economic security, institutional components, institutional mechanism, risks, threats.
Biologia w poszukiwaniu eliksiru młodości
Authors: Sikora Ewa
Published: February 2025

Without abstract
Drugie życie psychodelików
Authors: Gołembiowska Krystyna , Kamińska Katarzyna
Published: February 2025

Psychedelics known for mankind from millennia are class of compounds that alter consciousness, affect perception and produce hallucinations. Classic psychedelics such as psilocybin, mescaline, dimethyltryptamine (DMT) and lysergic acid diethylamide (LSD)  have pharmacodynamic serotonergic effects. They are known to exert profound effects on neuroplasticity i.e. alteration of neuronal structure and function. The psychoplastogenic properties led to their potential in treatment of depression, neurodegenerative disorders such as Alzheimer’s Disease, recovery after stroke and in schizophrenia. The role of microdosing regarded as 10% of the dose that elicits psychedelic effects needs extensive investigation.
Psychodeliki – czym są, jak działają i jaka jest ich przyszłość w medycynie
Authors: Gołembiowska Krystyna
Published: February 2025

Editorial
Numerical study of LED-pumped Nd:KGW laser
Authors: Shermatova Feruza , Payziyev Shermakhamat , Sherniyozov Anvarjon
Published: February 2025

In this study, we conducted a numerical analysis of LED-pumped solid-state lasers. We developed a simulation model for LED-pumped Nd:KGW and Nd:YAG lasers, incorporating a “five-way” pumping module. The spectral and laser characteristics of Nd:KGW were analyzed. Our results indicate that Nd:KGW crystals may be more suitable for LED pumping compared to the widely used Nd:YAG, as evidenced by their comparative performance. LED pumped Nd:KGW laser showed higher slope efficiency. We provide estimates for the laser output and absorption distribution. The study explores the influence of Nd concentration levels within Nd:KGW on laser outputs when employing LED pumping, while also addressing thermal considerations in Nd:KGW rods.