bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular and Cellular Mechanisms Involved in Aortic Wall Aneurysm Development
Authors: Bararu Bojan (Bararu) Iris , Pleșoianu Carmen Elena , Badulescu Oana Viola , Vladeanu Maria Cristina , Badescu Minerva Codruta , Iliescu Dan , Bojan Andrei , Ciocoiu Manuela
Published: January 2023

Aortic aneurysms represent a very common pathology that can affect any segment of the aorta. These types of aneurysms can be localized on the thoracic segment or on the abdominal portion, with the latter being more frequent. Though there are similarities between thoracic and abdominal aortic aneurysms, these pathologies are distinct entities. In this article, we undertook a review regarding the different mechanisms that can lead to the development of aortic aneurysm, and we tried to identify the different manners of treatment. For a long time, aortic wall aneurysms may evolve in an asymptomatic manner, but this progressive dilatation of the aneurysm can lead to a potentially fatal complication consisting in aortic rupture. Because there are limited therapies that may delay or prevent the development of acute aortic syndromes, surgical management remains the most common manner of treatment. Even though, surgical management has improved much in the last years, thus becoming less invasive and sophisticated, the morbi-mortality linked to these therapies remains increased. The identification of the cellular and molecular networks triggering the formation of aneurysm would permit the discovery of modern therapeutic targets. Molecular and cellular mechanisms are gaining a bigger importance in the complex pathogenesis of aortic aneurysms. Future studies must be developed to compare the findings seen in human tissue and animal models of aortic aneurysm, so that clinically relevant conclusions about the aortic aneurysm formation and the pharmacological possibility of pathogenic pathways blockage can be drawn.
Seismoelectric Effect of Oil-Wetted Porous Media Containing Two-Phase Flow
Authors: Zhao Yongpeng , Sun Xiangyang , Nie Zaiping
Published: January 2023

In oil reservoirs, if oil mainly has wettability in the solid phase, such as in carbonate reservoirs, the medium is oil-wetted. For oil-wetted porous media containing an oil and water two-phase flow, there are electric double layers at both the oil–solid interface and the oil–water interface, which can stimulate the seismoelectric effect. To date, most of the studies on the seismoelectric effects of porous media have mainly focused on water-wetted porous media, however, there are few reported studies on cases of oil-wetted porous media, especially on oil-wetted porous media containing an oil–water two-phase flow. In this paper, we adopted the oil-wetted pore model, in which oil and water are assumed to be immiscible, and each phase is continuous and distributed in parallel. We also considered the influence of the electric double layer at both the oil–solid interface and the oil–water interface on the seismoelectric effect. It was concluded that the seismoelectric effect of oil-wetted porous media containing a two-phase flow is mainly caused by the electric double layer at the oil–water interface, while the effect of the electric double layer at the oil–solid interface can be ignored. We regarded the two-phase flow as an equivalent fluid, and then we derived a governing equation of the seismoelectric effect and proposed the flux-averaging method to derive the electrokinetic coupling coefficients under the excitation of a steady acoustic field and a time-harmonic acoustic field. We also investigated the effects of formation parameters, namely, water saturation, pore size, water viscosity and porosity, on the seismoelectric effect, which can provide a theoretical reference for the study of seismoelectric logging in oil-wetted porous formations containing a two-phase flow.
Ischemic Stroke Induces Skeletal Muscle Damage and Alters Transcriptome Profile in Rats
Authors: Qi Hu , Li Xiangyu , Zhang Xiumeng , Li Bin , Tian Dan , Wang Dejian , Yang Ruocong , Zeng Nan
Published: January 2023

To establish pathological features of skeletal muscle post-stroke and to provide a background for promising interventions. Adult male SD rats were selected and randomly divided into a control group, a sham group, and a middle cerebral artery occlusion (MCAO) group. The tolerance and capability of exercise were separately collected on days 1, 3, 5, and 7 after the MCAO operation. The neurological deficits, brain infarct volume, soleus histopathology, mRNA-seq analysis, flow cytometry, immunofluorescence, and protein expression analysis were performed on the seventh day. Rats in the MCAO group showed that soleus tissue weight, pulling force, exercise capacity, endurance, and muscle structure were significantly decreased. Moreover, the RNA sequencing array revealed that mitochondrial-mediated autophagy was the critical pathological process, and the result of transcriptomic findings was confirmed at the translational level. The mitochondrial membrane potential and the mfn2 and p62 protein expression were decreased, and the Beclin-1, ATG5, Parkin, PINK1, LC3B, and Drp1 expression were upregulated; these results were consistent with immunohistochemistry. This is the first report on the pathological features of limbic symptoms on day 7 after MCAO surgery in rats. In addition, we further confirmed that autophagy is one of the main causative mechanisms of reduced muscle function after stroke.
Sentinel Lymph Node Biopsy in Malignant Melanoma of the Head and Neck: A Single Center Experience
Authors: Rubatto Marco , Picciotto Franco , Moirano Giovenale , Fruttero Enrico , Caliendo Virginia , Borriello Silvia , Sciamarrelli Nadia , Fava Paolo , Senetta Rebecca , Lesca Adriana , Sapino Anna , Deandreis Désirée , Ribero Simone , Quaglino Pietro
Published: January 2023

Purpose: This study evaluated the characteristics of patients with head and neck (H&N) melanoma who underwent sentinel lymph node biopsy (SNLB) and assessed the clinical course of patients categorizing subjects according to SLNB status and melanoma location (scalp area vs. non-scalp areas). Methods: Patients undergoing SLNB for melanoma of H&N from 2015 to 2021 were prospectively characterized according to sentinel lymph node (SLN) status. SPECT/CT had been previously performed. Patients were followed until the first adverse event to evaluate progression-free survival. Results: 93 patients were enrolled. SLNB was negative in 75 patients. The median Breslow index was higher for patients with positive SLNB compared with patients with negative SLNB. In addition, the Breslow index was higher for melanoma of the scalp compared with non-scalp melanoma. The median follow-up was 24.8 months. Progression occurred at the systemic level in the 62.5% of cases. There was a significant association between positive SLNB and progression (p-value < 0.01) of disease, with lower progression-free survival for patients with melanoma of the scalp compared with those with melanoma at other anatomic sites (p-value: 0.15). Conclusions: Scalp melanomas are more aggressive than other types of H&N melanomas. Sentinel lymph node status is the strongest prognostic criterion for recurrence.
The Influence of Preoperative Nutritional and Systemic Inflammatory Status on Perioperative Outcomes following Da Vinci Robot-Assisted Thoracic Lung Cancer Surgery
Authors: Moreno Camilo , Ureña Anna , Macia Ivan , Rivas Francisco , Déniz Carlos , Muñoz Anna , Serratosa Ines , Poltorak Violeta , Moya-Guerola Miguel , Masuet-Aumatell Cristina , Escobar Ignacio , Ramos Ricard
Published: January 2023

Background: Nutrition is an important factor in the outcome of any disease process. We evaluated the relationship of nutritional status and inflammatory status of non-small cell lung cancer (NSCLC) patients undergoing robotic-assisted thoracic surgery (RATS) with postoperative complications. Methods: This prospective cohort study included 107 NSCLC patients undergoing surgical treatment, between 2019 and 2021. Nutritional status and inflammatory status were assessed before pulmonary resection using anthropometric assessment, blood tests, and body mass index (BMI). Results: The BMI was 27.5 ± 4.4. Based on BMI, 29% (n = 31) were classified as normal weight, 43% (n = 46) as overweight, and 28% (n = 30) as obese. The mean neutrophil/lymphocyte ratio (NLR) was 2.16 ± 0.85, the platelet/lymphocyte ratio (PLR) was 121.59 ± 44.21, and the lymphocyte/monocyte ratio (LMR) was 3.52 ± 1.17. There was no increase in the number of intraoperative complications or bleeding (p = 0.696), postoperative complications (p = 0.569), mean hospital stay (p = 0.258) or duration of chest drain (p = 0.369). Higher inflammatory status, with an NLR > 1.84, was associated with more overall postoperative complications (p = 0.028), only in univariate analysis, but this significance was not maintained on multivariate analysis. Conclusions: BMI was not a predictor of increased postoperative risk in this cohort; therefore, weight should not deter surgeons from using RATS for pulmonary resection.
Factors Associated with Unplanned Transfer of Patients with Brain Tumor from Inpatient Rehabilitation Unit to Primary Acute Care Units
Authors: Nam Gyoung Ho , Chang Won Hyuk
Published: January 2023

Inpatient rehabilitation should be assessed to improve each functional domain in patients with brain tumor. However, no previous study has reported risk factors for unplanned transfer of this patient population to primary acute care units during a comprehensive inpatient rehabilitation. The objective of this study was to investigate the percentage of unplanned transfer of brain tumor rehabilitation inpatients to primary acute care units compared with stroke patients and factors associated with such unplanned transfer. Data of 137 patients with brain tumor who were transferred to the department of physical and rehabilitation medicine were retrospectively reviewed. For comparison, data of 438 patients with subacute stroke were also obtained. Included patients were divided into an unplanned transfer group and a control group based on whether they required a transfer to another department for acute care before completing their comprehensive inpatient rehabilitation. Reasons for unplanned transfers were classified based on medical or surgical conditions. The incidence of unplanned transfers to the medical or surgical department was significantly higher in patients with brain tumor (15.3%) than in stroke patients (7.1%) (p < 0.05). Most of unplanned transfers occurred within two weeks of the comprehensive inpatient rehabilitation for patients with brain tumor. There was a significantly higher incidence of unplanned transfers in patients with a primary tumor than in those with a metastatic tumor (15.9% vs. 4.8%, p < 0.05). In addition, the frequency of chemotherapy or radiotherapy was significantly (p < 0.05) higher in the unplanned transfer group than in the control group. The most common cause of an unplanned transfer was a neurologic cause (90.0%) in patients with brain tumor and an infectious disease such as pneumonia (51.6%) in stroke patients. In conclusion, these results demonstrated a higher incidence of unplanned transfers in patients with brain tumor than in stroke patients during intensive inpatient rehabilitation. Proportions of those with neurological problems were relatively higher in patients with brain tumor than in patients with subacute stroke.
Floristic Composition, Diversity, Palatability, and Forage Availability of Forest Rangelands in the Southern Mediterranean Region of Northern Morocco
Authors: Chebli Youssef , Chentouf Mouad , Cabaraux Jean-François , El Otmani Samira
Published: January 2023

Forest rangelands are an important component of extensive goat production in the Mediterranean region. The aim of this study was to survey the floristic composition, lifespan, life forms, phytogeographic relationships, palatability degree, and forage availability of forest rangelands in Northern Morocco. To achieve this goal, a plant species inventory was carried out, and a digital herbarium was constructed. Forage availability was estimated using the quadrat method. According to the results, 358 taxa were recorded with 228 genera and 66 families. The flora is mainly dominated by Asteraceae, Fabaceae, Poaceae, and Lamiaceae families. Six principal life forms of plants were recognized with the predominance of therophytes (48.3%). The Mediterranean floristic category was the most dominant in the flora (73.7%) with 264 species. The palatability degree was studied for 95 taxa, known by herders. The palatable plant group was highly represented with 32 species. Of these identified taxa, 93% were evaluated as potential sources of forage for grazing animals. The forage availability depended considerably on the season and the existing plant species (p < 0.01). The spring recorded the higher value with 3143 kg DM/ha. In conclusion, forest rangelands have a high biodiversity, which they need for rigorous protection to preserve their floristic composition and diversity.
Assessing the Combined Effects of Transportation Infrastructure on Regional Tourism Development in China Using a Spatial Econometric Model (GWPR)
Authors: Shen Pengxia , Yin Ping , Niu Bingjie
Published: January 2023

Transportation infrastructure plays an important role in tourism, and the spatial econometric model (GWPR) can offer quantitative support for regionalized development policies in transportation infrastructure. Panel data from 30 provinces were collected for a decade before the COVID-19 pandemic. We show that the GWPR model is a superior tool for assessing the combined impact of transportation infrastructure on tourism and its spatial heterogeneity. The effects of transportation infrastructure on tourism have historically been overwhelmingly positive, with the positive effect of high-speed rail expanding over the decade, while the positive effect of air travel contracted. The combined effects of transportation infrastructure vary across space and time. Additionally, the evolution of the effects exhibits spatial heterogeneity. The 30 provinces in this study are categorized into five types, and targeted implementation strategies for transportation infrastructure are formulated.
Biodiversity and Interannual Variation of Harmful Algal Bloom Species in the Coastal Sea of Qinhuangdao, China
Authors: Chen Yang , Wang Lu , Liu Zhiliang , Su Du , Wang Yibo , Qi Yanping
Published: January 2023

For the frequent occurrence of harmful algal blooms (HABs) in the Qinhuangdao coastal sea (QCS) of the Bohai Sea in summer, we tested the hypothesis that high-biodiversity HAB species exist in the area, and a series of censuses of HAB species were conducted in the QCS in the summers of 2014–2019. Through morphological identification, we found 100 algae species representing 42 genera in 3 phytoplankton phyla in this study, among which Bacillariophyta was the most dominant phylum. We also found that the population density of Dinoflagellata increased from 2016 to 2019. In total, 59 HAB species were annotated in this study, including 39 of Bacillariophyta, 18 of Dinoflagellata and 2 of Ochrophyta, of which 13 HAB species were reported in the Bohai Sea for the first time, and most HAB species were widely distributed in the QCS in summer. Notably, four dominant HAB species displayed unique temporal and spatial distribution characteristics, while their distribution ranges and population densities increased from 2014 to 2019. The distributions of five environmental factors were different in the QCS, while the temperature, salinity, and dissolved inorganic nitrogen might be the key environmental factors influencing the distribution of dominant HAB species in the summer. In conclusion, this study provides a detailed evaluation of phytoplankton diversity and interannual variation in the QCS. The existence of a high level of biodiversity of algal bloom species suggests the need for long-term monitoring in order to further study and prevent potential HABs.
Ultrasonic Correction Measurement for Residual Stress in 5083 Aluminum Alloy Welded Component of High-Speed Train
Authors: Guo Mocheng , Gou Guoqing , Chen Bing , Qiu Feifei , Zhu Zhongyin , Jin Junjun , Wu Xiangyang , Gao Wei , Sun Songling
Published: January 2023

The measurement and control of residual stresses are crucial to the structural safety of high-speed trains. The critical refraction longitudinal wave method is extensively employed for the residual stress measurement, and the correction of the influencing factors is the key to the detection accuracy. However, the existing methods mostly give purely mathematical expressions which are only applicable to their studied materials. Hence, this paper proposes the specific influence factor correction method to enhance the applicability and accuracy, and the 5083 aluminum alloy welded component is utilized for testing. Subsequently, the stress coefficient K and the compensation acoustic time under the influence of internal factors are obtained by employing the proposed method, combined with the simulation to determine the focused detection zone, the hole-drilling and X-ray methods are utilized for comparisons, and the results indicate that the test data have a good coincidence. Meanwhile, the detection errors of each zone before and after the correction are analyzed. Moreover, combined with the experimental verification, it is found that the penetration depth of a critical refraction longitudinal wave approaches its one wavelength; the corresponding study is conducted with this characteristic and concludes that in the weld zone, the longitudinal residual stresses are mainly concentrated on the surface of the measured material. Finally, the above results indicate that the proposed method can provide more accurate measurements for engineering applications.
Enhanced Visible-Light-Responsive Photocatalytic Degradation of Ciprofloxacin by the CuxO/Metal-Organic Framework Hybrid Nanocomposite
Authors: Tsai Cheng-Kuo , Huang Ching-Hsuan , Horng Jao-Jia , Ong Hui Lin , Doong Ruey-An
Published: January 2023

Ciprofloxacin (CIP) is a commonly used antibiotic, however, once in the environment, it is highly toxic with a poor biodegradability. Given these attributes, an effective strategy for the removal of CIP is urgently needed for the protection of water resources. Herein, a novel copper metal-organic framework (CuxO/MOF) multifunctional material has been produced, in this work, by the calcination of Cu-MOF urea at 300 °C, in the presence of a 5% H2 atmosphere. The morphological, structural, and thermal properties of the prepared CuxO/MOF were determined through various techniques, and its photocatalytic behavior was investigated for the degradation of CIP under visible-light irradiation. The prepared CuxO/MOF bifunctional material is presented as a graphitic carbon-layered structure with a particle size of 9.2 ± 2.1 nm. The existence of CuO-Cu2O-C, which was found on the CuxO/MOF surface, enhanced the adsorption efficiency and increased the photosensitivity of CuxO/MOF, towards the degradation of CIP in aqueous solutions. The tailored CuxO/MOF, not only shows an excellent CIP degradation efficiency of up to 92% with a constant kinetic rate (kobs) of 0.048 min−1 under visible light, but it can also retain the stable photodegradation efficiency of >85%, for at least six cycles. In addition, CuxO/MOF has an excellent adsorption capacity at pH 6.0 of the maximum Langmuir adsorption capacity of 34.5 mg g−1 for CIP. The results obtained in this study demonstrate that CuxO/MOF is a reliable integrated material and serves as an adsorbent and photocatalyst, which can open a new pathway for the preparation of visible-light-responsive photocatalysts, for the removal of antibiotics and other emerging pollutants.
The Journey of a Medicinal Plant throughout Science: Sphaeralcea angustifolia (Cav.) G. Don (Malvaceae)
Authors: Meckes-Fischer Mariana , Nicasio-Torres Pilar
Published: January 2023

Using herbal medicine is an ancestral cultural practice among Mexicans. A broad sector of society turns to plants to treat priority health problems, a reality that leads scientists to explore the healing value attributed to them. Advances in the experimental research of Sphaeralcea angustifolia confirmed the anti-inflammatory activity of the species; therefore, an analysis of the scope of these studies is now warranted. As such, this paper is a compendium of the advances published in the scientific literature (from 2004 to 2021) on the anti-inflammatory properties of this plant. The promise offered by the species as a potential therapeutic agent is also considered, without dismissing aspects necessary for the preservation of this resource and its cultural and physical environment. The chemical–pharmacological aspects of the wild plant and its in vitro culture are highlighted. The plant’s anti-inflammatory properties support its clinical application as an anti-inflammatory phytopharmaceutical to treat arthritic conditions. The sustained therapeutic potential of S. angustifolia is reinforced by the biotechnological processes designed to conserve the resource, thus contributing to the protection of biodiversity and cultural diversity, aspects distinctive of a megadiverse country such as Mexico.
Pengaruh Rasio Kecukupan Modal dan Margin Bunga Bersih Terhadap Tingkat Pengembalian Aset
Authors: Fauziah Dini , Diana Nana
Published: January 2023

This research aims to determine the effect of the capital adequacy ratio and net interest margin on the rate of return on assets at state-owned banks for the 2014-2021 period. In sampling using saturated samples. Sample data obtained from the bank's website. The technique used is multiple linear regression analysis. The result of the research is that partially, the capital adequacy ratio does not significantly affect the rate of return on assets, while the net interest margin significantly affects the rate of return on assets. Simultaneously, these two variables have an influence on the rate of return on assets.
Analisis Produk Unggulan Daerah Di Kabupaten Jepara
Authors: Anam A Khoirul , Widiastuti Elly , Nugroho Aji , Suharwati Anik , Fatchiyyah Amalia Rachma
Published: January 2023

This study aims to analyze and map local superior commodities (LSC) in Jepara Regency using Shift Share Analysis, Growth Ratio Model Analysis (MRP), Location Quotient (LQ) Analysis, Overlay Analysis, and Klassen Typology Analysis. The analysis was carried out using the GRDP data for Jepara Regency and for Central Java Province. The research was conducted on five business sectors including the creative industry sector, the food processing sector, the food crop & plantation product processing sector, the fishery product processing sector and the agricultural product processing sector. The results of the identification of superior commodities in Jepara Regency show that the manufacturing sector has strong competitiveness or has a highly competitive advantage. It implies that local governments need to pay attention to business sectors that are experiencing a decline and relatively underdeveloped, improve managerial capabilities for business actors, especially in the manufacturing industry sector, and increase market access offline and online (omni), as well as develop innovation hubs.
O "Livro de Plantas" de Hildegarda de Bingen
Authors: Martins Maria Cristina da Silva
Published: January 2023

Este trabalho tem como objetivo divulgar o Livro de Plantas de Hildegarda de Bingen, abadessa alemã do século XII, e mostrar parte da tradução desse livro que está sendo realizada do latim ao português. O Livro de Plantas (Liber I: de plantis) é o primeiro dos nove livros que compõem o tratado científico Physica (Liber simplicis medicinae), de autoria dessa santa católica
Um breve estudo sobre o prólogo da écloga X de Virgílio
Authors: Hanashiro D. M. de G. , Nogueira Érico
Published: January 2023

Nesse artigo, pretendemos estudar o prólogo da écloga X de Virgílio por meio de uma tradução nossa. O propósito é compreender como se manifestam as relações de sentido entre os elementos que o compõem. Assim, norteados pelos conceitos de arte alusiva e intertextualidade, interessa-nos identificar principalmente os lugares-comuns e as alusões a obras e a poetas modelares, para apresentar uma interpretação possível.
Meeting Different Needs. The Implied Readers of the ‘Pythagorean’ Kingship Treatises
Authors: Trapp Michael
Published: January 2023

Cet article propose une approche comparative des traités «pythagoriciens » sur la royauté, centrée sur une réflexion sur leur place au sein de l’offre plus vaste d’ouvrages sur la royauté disponibles à la fin de l’époque hellénistique et à l’époque impériale, ainsi que sur leur lectorat implicite. La comparaison avec les discours Sur la royauté de Dion Chrysostome permet de définir plus précisément ce que les traités offrent ou non au lecteur, mais il faut également développer des comparaisons avec d’autres textes «rivaux » et avoir un aperçu de la variété des communautés de lecteurs pour cette période.
Perspectivas para o Hidrogênio Verde: uma análise à luz do modelo da Hélice Tríplice
Authors: Ribeiro Filho José de Ribamar , Tahim Elda Fontinele , Veras Vanessa Maria Vasconcelos
Published: January 2023

Esta pesquisa tem por objetivo contribuir para estudos das perspectivas sobre o Hidrogênio Verde sob a ótica do modelo da Hélice Tríplice da Inovação (Universidade — Indústria — Governo) desenvolvido por Etzkowitzv (1990), Etzkowitz e Leydesdorff (1995), identificando o caminho para a configuração do modelo conforme padrões opostos: modelo estatista, onde o governo detém o controle da academia e da indústria, e; modelo laissez-faire, em que universidade, indústria e governo interagem de forma modesta, estando separados por firmes fronteiras, como explicam  Etzkowitz e Zhou  (2017). Foi enredado como seu objeto de pesquisa o contexto de desenvolvimento de cenários para o desenvolvimento do Hidrogênio Verde no estado do Ceará, que envolvem sua produção, uso, transporte, armazenamento, bem como o comércio no mercado nacional e sua exportação.  Um grupo de especialistas com representantes das três hélices foi elencado para as entrevistas, que seguiram um roteiro semiestruturado. Trata-se de uma pesquisa com abordagem de cunho qualitativo com apropriação da estratégia de investigação estudo de caso descritivo. As análises dos dados foram realizadas por intermédio de uma Análise Proposicional do Discurso (APD), técnica que identifica “universo de referências” adaptando-se a materiais verbais produzidos em entrevistas, conforme Bardin (2016), contando com o auxílio do software Iramuteq para formação de classes e segmentos de textos. Em conclusão foi observado que as interações entre as três esferas que compõem o modelo, para o caso do cenário do Hidrogênio Verde no estado do Ceará, têm ocorrências desde sua idealização, o que estabelece que o caminho da formação da Hélice Tríplice não corresponde a qualquer um dos dois exemplares, estatista ou “laissez-faire”. Desdobramentos da Hélice Tríplice (quádrupla e quíntupla) podem estabelecer conexões com este estudo em pesquisas futuras.
Aborto: uma revisão integrativa acerca da sua realização sob a ótica jurídica e social
Authors: Oliveira Sharon Cardoso Cândido de , Melchiades Rubiane Basilichi , Borges Silvio Rodrigo , Duran Thais Camila Alves Lessa
Published: January 2023

A Organização Mundial de Saúde (OMS) define o aborto inseguro como um procedimento para interromper a gravidez realizado por pessoas sem as habilidades necessárias e/ou em um ambiente sem os requisitos para a realização de procedimentos médicos. No Brasil, cujo percentual de gestações não planejadas é elevado, os casos de abortos entre as mulheres é uma realidade incontestável, realizado muitas vezes de forma clandestina, em condições desprovidas de segurança, implicando em um problema de saúde pública, tanto por sua magnitude quanto por sua persistência. A partir do momento em que os métodos de aborto se tornaram seguros, as leis focaram apenas no sentido de serem punitivos e dissuasivos, ou para proteger a vida fetal em detrimento da vida das mulheres. Além disso, legalmente só existem três hipóteses de abortos permitidos no Brasil: em caso de anencefalia, estupro da mãe ou em caso de risco de morte materna. Sob a ótica social, a principal opção é a prevenção de gravidezes indesejadas por meio de intervenções educacionais, acesso às informações e métodos contraceptivos, assim como a provisão rápida e fácil de serviços de abortamento seguro para todas aquelas com gestações indesejadas.
Análise dos registros de controle populacional dos gatos livres no Porto de Santos
Authors: Guimarães Juliana Plácido , Chucri Thaís Martins , Siqueira Vinícius Campregher , Silva Julia Cupertino Pereira da
Published: January 2023

O alto número de felinos presentes nas áreas do Porto de Santos se tornou uma preocupação para os profissionais da vigilância sanitária, visto que esses animais representam risco de transmissão de zoonoses, acidentes por mordedura e/ou arranhadura e desequilíbrio ambiental. Dessa forma, em 2011 a Autoridade Portuária de Santos (SPA) criou um programa de controle populacional para solucionar essa problemática, utilizando o protocolo CED, que consiste na captura, esterilização, imunização e destinação do animal. Este estudo verificou os registros de capturas do programa, de janeiro de 2021 a maio de 2022 e dos cinco anos anteriores, a fim de comparar os números obtidos. Como resultado, foi possível observar um aumento no número de animais capturados entre 2021 e 2022, o que pode ser justificado pela alta taxa de abandonos que enfrentamos atualmente e, também, pelo baixo nível de conscientização da população sobre guarda responsável. Portanto, conclui-se que um programa de controle populacional compreende, além da esterilização, esferas da Saúde Única, onde o médico veterinário atua na integração da medicina humana, medicina veterinária e saúde ambiental, com a finalidade de beneficiar, não somente os animais, mas também os seres humanos, prevenindo e controlando doenças zoonóticas e promovendo bem-estar aos animais errantes.
Definição e instanciação de um processo híbrido SCRUM e RUP aderente ao ciclo PDCA
Authors: Da Silva Sabrina , Portela Carlos dos Santos , Pereira Rodrigo Lisbôa , Yasojima Edson Koiti Kudo , De Brito Junior Albino Rodrigues , Cordeiro Thiago Damasceno
Published: January 2023

Uma das principais maneiras de lidar com problemas recorrentes em projetos de software consiste na adoção de frameworks de gestão de processo. No entanto, há projetos que são mais adequados às metodologias tradicionais e outros às metodologias ágeis. Algumas empresas têm combinado práticas tradicionais e ágeis em modelos híbridos de gestão de projetos. Neste contexto, este artigo apresenta uma pesquisa-ação que resultou na definição e instanciação de um processo híbrido constituído de práticas provenientes dos frameworks SCRUM e RUP em um projeto real de desenvolvimento de software. Esse processo foi avaliado através da técnica de revisão por pares, demonstrando-se satisfatório no seguimento das premissas de ambos os frameworks, na gestão do projeto e no atendimento do ciclo Plan, Do, Check e Act (PDCA). Por fim, foi feita a análise SWOT do processo pela equipe que seguiu suas atividades no projeto-alvo da pesquisa.
Anodontia de dentes permanentes: uma revisão integrativa
Authors: Peixoto Áyla Geovânia da Silva , Peixoto Franklin Flamarion Gomes , Taveiros Dannyellen Maria de Siqueira Gomes , De Souza Juliana Vilela Ribeiro
Published: January 2023

Entende-se por agenesia o decréscimo em número dentário de um ou mais elementos. Ou seja, consiste na ausência de dentes seja na dentição decídua ou permanente. Entende-se também que a agenesia dentária é uma anomalia congênita que consiste na ausência de um ou mais dentes e apresenta-se como uma alteração de desenvolvimento dentário bastante comum na população em geral. Frente ao que foi descrito acima, o presente trabalho possui por objetivo fazer uma revisão literária sobre Anodontia em dentes permanentes. A metodologia para compor o trabalho por ora apresentado foi um estudo exploratório descritivo, desenvolvido por meio de uma revisão sistemática que teve como foco investigativo realizar um levantamento bibliográfico que trouxesse esclarecimentos sobre a agenesia em dentes permanentes. As buscas foram realizadas entre outubro e novembro de 2021 e foram utilizados os bancos de dados eletrônicos das seguintes plataformas: National Library of Medicine (PubMed), Literatura Latino-Americana e do Caribe em ciências da saúde (LILACS) e Scientific Electronic Library (SCIELO) e MEDLINE.
Patologia benigna e benefícios da laparoscopia na cirurgia urológica
Authors: Menezes Marina Santos , Tanaka Ivan Kenji , Vicini Vanessa Francescatto , Prates Camila Aguilar , Moreira Stephanie Figueiredo de Barros , Pires Lorena Virgínia Ferreira , Barros Lucas Silva , Silva Alessandra da , Chaves Luiz Lima , Teixeira Camilla Carmem , Teixeira Fernando César , Gonçalves Laise Fernandes Holanda , Alves Clarice Ágata , Neto José de Ribamar da Silva Garrido
Published: January 2023

A laparoscopia, também conhecida como cirurgia de buraco da fechadura, é a arte de realizar cirurgias por meio de pequenas incisões de 0,5 a 1,5 cm, usando pequenos instrumentos telescópicos especializados. Um laparoscópio é um tubo estreito com uma câmera e lentes acopladas a ele. As vantagens da cirurgia laparoscópica sobre a tradicional cirurgia de incisão aberta incluem diminuição da dor pós-operatória, diminuição do sangramento, menor tempo de internação, convalescença e recuperação mais precoces, com complicações como infecções pulmonares, coágulos nas pernas e pulmões minimizados com a mobilização precoce. Este estudo teve como objetivo analisar os benefícios da laparoscopia na cirurgia urológica em caso de patologia benigna. Para isso, foi desenvolvida uma revisão integrativa de literatura, realizando-se a seleção de fontes de estudo nas bases de dados Medline e Lilacs. Com base na análise qualitativa de dados, concluiu-se que a laparoscopia na cirurgia urológica em patologias benignas apresenta uma série de benefícios ao serem comparadas a cirurgias abertas convencionais, tais como: menor sangramento, diminuição da morbidade operatória, alta hospitalar precoce, menor dor no pós-operatório, efeitos estéticos mais adequados e retomada precoce das atividades habituais. No caso de pessoas Testemunhas de Jeová, registram-se menores níveis de sangramento e redução da necessidade de transfusão.
Age- and Microbiota-Dependent Cell Stemness Plasticity Revealed by Cattle Cell Landscape
Authors: Wu Jia-Jin , Zhu Senlin , Tang Yi-Fan , Gu Fengfei , Valencak Teresa G. , Liu Jian-Xin , Sun Hui-Zeng
Published: January 2023

Newborn ruminants are considered functionally monogastric animals. The poor understanding of cellular differences between newborn and mature ruminants prevents the improvement of health and performance of domestic ruminants. Here, we performed the single-cell RNA sequencing on the rumen, reticulum, omasum, abomasum, duodenum, jejunum, ileum, cecum, colon, rectum, liver, salivary gland, and mammary gland from newborn and adult cattle. A comprehensive single-cell transcriptomic atlas covering 235,941 high-quality single cells and 78 cell types was deciphered. A Cattle Cell Landscape database (
http://cattlecelllandscape.zju.edu.cn
) was established to elaborately display the data and facilitate effective annotation of cattle cell types and subtypes for the broad research community. By measuring stemness states of epithelial cells in each tissue type, we revealed that the epithelial cells from newborn forestomach (rumen, reticulum, and omasum) were more transcriptionally indistinct and stochastic compared with the adult stage, which was in contrast to those of abomasum and intestinal tissues. The rapid forestomach development during the early life of calves was driven by epithelial progenitor-like cells with high DNA repair activities and methylation. Moreover, in the forestomach tissues of newborn calves, the
Megasphaera
genus was involved in regulating the transcriptional plasticity of the epithelial progenitor-like cells by DNA methylation regulation. A novel cell type, the

STOML3
+

cell, was found to be newborn-specific. It apparently plays a crucial role in stemness maintenance of its own and cholangiocytes in the hepatic microenvironment. Our results reveal that the age- and microbiota-dependent cell stemness plasticity drives the postnatal functional maturity of ruminants.
Analisis Perbandingan Optimizer pada Arsitektur NASNetMobile Convolutional Neural Network untuk Klasifikasi Ras Kucing
Authors: Nur Cahyo D. Diffran , Anwar Fauzi Muhammad , Tri Nugroho Jangkung , Kusrini Kusrini
Published: January 2023

Searching for research titles and abstracts is made easy with these keywords. Artificial Intelligence (AI) technology is currently developing very rapidly, there are various applications of AI that we can find in everyday life around us without realizing it. AI technology now allows us to work with computers more easily, just as we can know the type of cat breed and other information. There is deep learning that works by imitating the human brain or artificial neural networks to enhance current machine-learning capabilities. Deep learning can recognize and classify image categories. This study aims to determine the optimal optimizer in the classification of cat breeds. With the classification of cat breeds, cat keepers can find out the type of cat breed so they can find out how to care for it, the activities, and the personality possessed by the cat. The use of algorithm method used in this study uses the CNN algorithm with the NASNetMobile architecture. The dataset contains 840 images which are divided into 4 classes and divided into 588 training data, 168 testing data, and 84 validation data. for the RMSprop optimizer with a learning rate of 0.0001 to get an accuracy of 89.88%, this result is the highest among the others. Meanwhile, the SGD optimizer gets an accuracy of 78.57 & this result is the lowest. So it can be concluded that the architecture and optimizer are very important and influential in improving the performance of the model.
Repensar las prácticas pedagógicas en la primera infancia desde la inclusión y diversidad
Authors: Canizales Bonilla Julieth Tatiana , Zúñiga Trujillo Yudy Mercedes , Henao Morales Laura Yamile
Published: January 2023

En el presente artículo se realiza un análisis y balance sobre los estudios, a nivel internacional, nacional (Colombia) y local (Tolima), que trabajan sobre la inclusión y diversidad en los niños y niñas de la primera infancia. El objetivo principal es desarrollar una revisión de antecedentes que permita conocer el papel de los docentes frente a la inclusión educativa y transformar el aula de clase en un espacio crítico, participativo y reflexivo. Dicho estado del arte se elabora bajo la identificación de metodologías, marcos teóricos y resultados, que permitan comprender ¿qué factores culturales, afectivos, sociales y educativos son influyentes en la inclusión educativa?
Ciudades imaginadas latinas en la era digital: caso Ibagué
Authors: Hernández-Cifuentes Tatiana , Martínez Aroca Yorladys , Lopera Molano Ángela María , Santana Sáenz Carlos Mauricio
Published: January 2023

La investigación Ciudades y comunidades imaginadas latinas en la era digital es la fase contemporánea del proyecto Imaginarios urbanos, a partir del cual Ibagué fue percibida y habitada por sus ciudadanos como ciudad musical, siguiendo la metodología propuesta por el investigador colombiano Armando Silva. Ahora, en esta nueva etapa, nos centramos en analizar los modos de ser, pensar y representar el mundo latino dentro del contexto universal, a partir de la comparación de los imaginarios urbanos de la capital musical de Colombia junto a otras ciudades y comunidades latinas en el mundo.
Participación de jóvenes de Ibagué en el Paro Nacional del 2021
Authors: Alba Sanabria Sandra Milena , Uribe Sarmiento John Jairo , Hernández Campos Arnulfo Jamith , Salamanca Santos María del Pilar , Sotelo Rodríguez María Paula , Morales García Laura , Moreno Salcedo Edward Fernando
Published: January 2023

En la ciudad de Ibagué, durante el periodo del 28 de abril a julio de 2021, se dieron movilizaciones sociales atípicas, protagonizadas, entre otros actores, por jóvenes que, desde variadas peticiones, buscaron agruparse en una reivindicación específica, ser un movimiento de oposición. El propósito del documento es generar una aproximación a la comprensión de la movilización social desde los y las jóvenes, por ello la estrategia metodológica estuvo guiada por la recopilación de información teórica, pero también experimental, de parte de cuatro jóvenes participantes activos de las movilizaciones. Como principales resultados se tiene que los jóvenes se integran al movimiento social desde la experiencia, a partir del aprendizaje construyen su identidad, esto es, sus agendas, sus contendores, sus reivindicaciones, su historicidad. Finalmente, a nivel nacional y regional, el contexto de oportunidades para movilizarse es cíclico, es decir que el Paro 2021 hace parte de un proceso movilizatorio, que a veces alcanza mayor o menor intensidad según las oportunidades del contexto.
En el Tolima se respiran Aromas de Paz
Authors: Cárdenas Cadena Valentina
Published: January 2023

Aromas de paz. Mujeres, café y desarrollo sostenible en el sur del Tolima, es un proyecto de cooperación internacional que trabaja de la mano con la Red de Mujeres Chaparralunas por la Paz y que tiene como objetivo contribuir al desarrollo rural sostenible y a la mejora de la calidad de vida de las mujeres cafeteras de los corregimientos La Marina y Calarma, del municipio de Chaparral, en el Sur del Tolima. Este proyecto contempla distintas acciones comunicativas, sociales, académicas y ambientales, que involucran actores locales, regionales, nacionales e internacionales para incentivar la construcción colectiva de una paz en los territorios.
ICOMOS International Cultural Tourism Charters 1976-2021: evolution, contributions and trends in cultural heritage protection
Authors: Martínez Yáñez Celia
Published: January 2023

Since its establishment in the sixties, the standard setting texts produced by ICOMOS have become the most reputed, influential and distributed documents concerning cultural heritage protection worldwide. An examination of all ICOMOS charters and recommendations makes clear the  indispensable role of this organisation to disseminating best conservation, restoration and management practices during the last sixty years. It also demonstrates its persistence to never give up to the countless pressures that challenge heritage preservation around the world. Tourism is undoubtedly one of the most important and global of these pressures due to its considerable influence at all levels of cultural heritage management and decision-making. This paper analyses the early, pioneer and crucial role of ICOMOS to promote responsible tourism through an evaluation of its international cultural tourism charters from 1976, when the first was adopted, until 2021, when the Advisory Council of the organisation has approved the ICOMOS Draft International Charter for Cultural Heritage Tourism (2021): Reinforcing cultural heritage protection and community resilience through responsible and sustainable tourism management for its adoption at the ICOMOS General Assembly in 2022. The long process for drafting and approving this Charter and its new conceptual approaches show the emerging trends affecting cultural heritage globally and allow reflecting more broadly about the future of standard setting texts on this subject.
STUDI KONFIGURASI POLITIK UU NOMOR 11 TAHUN 2020 TENTANG CIPTA KERJA: SEBUAH TINJAUAN LITERATUR
Authors: Risky Wahyudi Irianto
Published: January 2023

The purpose of this paper is to examine The Political Configuration Of Law Number 11 Of 2020 Concerning Employment Creation, which is expected to be a small part of efforts to recover the national economy, specifically in urging economic transformation so that it can generate jobs. The question is whether this intention is in line with or in accordance with the legal system in Indonesia in making laws and regulations. The method used is literature study or literature study, which contains theories relevant to the research problem. The Omnibus Law is a procedure for making statutory regulations and when viewed from the point of view of the legal system in Indonesia, the role of the Law as a result of the Omnibus Law procedure in the hierarchy of statutory regulations is the same as the Law. In terms of the form of government, in the view of the Omnibus Law, it can be said that democracy is the result of a merger between Polybius and Plato because the ultimate goal is the peace of the citizens. This merger means that democracy in Indonesia has meaning as a form of government in hindering state power.
Gulyás Adrienn, Mudriczki Judit, Sepsi Enikő, Horváth Géza (szerk.): Klasszikus művek újrafordítása
Authors: Nagy Nóra
Published: January 2023

A sokrétű és széles tematikájú kötet a Károli Gáspár Református Egyetemen 2018-ban és 2019-ben rendezett szakmai napok előadásainak és kerekasztal-beszélgetéseinek szerkesztett változatát adja közre.
Corrosion of structural materials for salt melt technologies
Authors: Rejková Jana , Kudrnová Marie
Published: January 2023

Molten salt mixtures are considered media for many modern technologies using their ability to store thermal energy, thermal stability at high temperatures, low melting point, and other properties. The disadvantage of their use is high corrosion aggressiveness towards metal structural materials. In particular, impurities contained in salt mixtures can significantly increase the corrosion rates of alloys. This paper compares the corrosion behaviour of Inconel 625, 321, 316L and 316Ti alloys in a mixture of chloride and nitrate salt melts. The parameters in which both mixtures are stable and in melt form were chosen -400 °C, an inert argon atmosphere, and a pressure of 0.2 MPa. After exposure, the state and composition of the surfaces were analysed by XPS (X-ray photoelectron spectroscopy) and SEM (Scanning Electron Microscopy). These materials are better suitable for nitrate salt environments, where only very thin surface layers were formed without local types of corrosion. In chloride melts, Alloy 321 and Inconel 625 have shown greater resistance than 316L and 316Ti stainless steels.
A CASE OF MORVANS SYNDROME ASSOCIATED WITH HEAVY METAL POISONING AFTER SIDDHA DRUG INTAKE
Authors: Guptha L.R Srinivasa , Mohan Nidin , Y Dayanandan , K.V Rajalakshmi , Kumar M Sathish
Published: January 2023

Morvan syndrome (MoS) or Morvan's fibrillary chorea (MFC) is an autoimmune-mediated syndrome that is frequently
associated with autoantibodies targeting contactin-associated protein-like 2 (CASPR2-Abs). It is often associated with
peripheral nerve hyperexcitability, autonomic instability and neuropathic pain. Here we report a case who presented
with Morvans syndrome after 4 months siddha drug intake.This case highlights the association of Morvans syndrome
with heavy metal poisoning and its incidental occurrence after siddha drug intake.