bluuebunny/crossref_metadata_2025 huggingface dataset:
Whole-genome sequence analysis of high-level penicillin-resistant strains and antimicrobial susceptibility of Neisseria gonorrhoeae clinical isolates from Thailand
Authors: Nokchan Natakorn , Wongsurawat Thidathip , Jenjaroenpun Piroon , Nitayanon Perapon , Tribuddharat Chanwit
Published: July 2022

Background

The increasing rate of antimicrobial-resistantNeisseria gonorrhoeaeposes a considerable public health threat due to the difficulty in treating gonococcal infections. This study examined antimicrobial resistance (AMR) to drugs recommended for gonorrhea treatment between 2015 and 2017, and the AMR determinants and genetic compositions of plasmids in 3 gonococcal strains with high-level penicillin resistance.

Methods

We collected 117N.gonorrhoeaeisolates from patients with gonococcal infections who attended Siriraj Hospital, Bangkok, Thailand, between 2015 and 2017. Minimum inhibitory concentrations (MICs) of penicillin, tetracycline, ciprofloxacin, azithromycin, spectinomycin, cefixime, and ceftriaxone were determined by the agar dilution method. PCR amplification and sequencing of 23S rRNA andmtrR(a negative regulator of MtrCDE efflux pump) were performed. Whole genomes of 3 PPNG strains with high-level penicillin resistance (MIC ≥ 128 μg/ml) were sequenced using Illumina and Nanopore sequencing platforms.

Results

The proportions ofN.gonorrhoeaeisolates with resistance were 84.6% for penicillin, 91.5% for tetracycline, and 96.6% for ciprofloxacin. All isolates were susceptible to spectinomycin, azithromycin, cefixime, and ceftriaxone. An adenine deletion within a 13 bp inverted repeat sequence in themtrRpromoter and an H105Y mutation in themtrRcoding region were found in theN.gonorrhoeaeisolate with the highest azithromycin MIC value (1 μg/ml). Three high-level penicillin-resistant isolates contained nonmosaic type IIpenAand had mutations inpenBand themtrRcoding region. All isolates with high-level penicillin resistance carried the conjugative plasmids with or without the Dutch typetetMdeterminant, the beta-lactamase plasmid (Rio/Toronto), and the cryptic plasmid.

Conclusions

The gonococcal population in Thailand showed high susceptibility to ceftriaxone and azithromycin, current dual therapy recommended for gonorrhea treatment. As elevated MIC of azithromycin has been observed in 1 strain ofN.gonorrhoeae, expanded and enhanced surveillance of antimicrobial susceptibility and study of genetic resistance determinants are essential to improve treatment guidelines.
Beyond arboviruses: A multicenter study to evaluate differential diagnosis of rash diseases and acute febrile illness cases in Rio de Janeiro, Brazil
Authors: Alves Arthur Daniel Rocha , Raposo Jéssica Vasques , de Sousa Rafaela Moraes Pereira , Cardoso Claudete Aparecida Araújo , Costa Pâmela Karla Simões de Freitas , Araújo Julienne Martins , Barreiro Sabrina Teresinha Alvim , Bressan Clarisse da Silveira , Calvet Guilherme Amaral , de Souza Rogério Valls , Brasil Patrícia , Cubel Garcia Rita de Cássia Nasser , Pinto Marcelo Alves , de Paula Vanessa Salete , Amado Luciane Almeida
Published: July 2022

Introduction

A wide variety of viruses can cause rash diseases (RDs) or acute febrile illness (AFIs) in children, adolescents and adults; however, approximately 19% of RD cases and 40% of AFI cases remain without a defined etiology. Parvovirus B19 (B19V) and herpesvirus infection can also cause RD and/or AFI, and in some risk groups, these infections can become persistent (or latent) and may require hospital treatment. Since these infections do not have mandatory reporting, they can be hidden by other diseases, such as those caused by arboviruses (e.g., dengue virus). In this context, the aim of this study was to pursue the differential laboratory diagnoses of B19V and herpesvirus infections in patients with RD and AFI, without a defined etiology, seen in hospitals and/or reference centers for infectious diseases in Rio de Janeiro.

Methods

A total of 114 participants were enrolled in the study, including 54 children and 60 adults. B19V infection was assessed by real-time PCR (qPCR) and ELISA (anti-B19V IgM and IgG). EBV was assessed through qPCR, and betaherpesviruses (HCMV, HHV-6 and HHV-7) were assessed through multiplex qPCR. Sociodemographic and clinical data were obtained from the medical record data of these participants.

Results

The median age of children with RD was 2 years (interquartile range (IQR): 5), and 55.6% were male. Among adults with AFI, the median age was 38 years (IQR: 21), and 56.7% were female. Regarding RD patients, viral prevalence (and load) were 5.5%(104IU/mL), 3.4%(104IU/mL), 5.5%(104IU/mL) and 11.1%(105IU/mL) for B19V, EBV, HCMV and HHV-6 infection, respectively, and in AFI patients they were 6.6%(105IU/mL), 1.6%(103IU/mL), 3.3%(104IU/mL) for B19V, HCMV and HHV-6, respectively. HHV-7 was not detected in RD or AFI patients.

Conclusion

These results suggest the importance of including B19V and herpesviruses in the differential laboratory diagnoses for patients with RD and AFI, not only for epidemiological purposes but also for the proper management of the patient.
Prospective audit and feedback implementation by a multidisciplinary antimicrobial stewardship team shortens the time to de-escalation of anti-MRSA agents
Authors: Yamaguchi Ryo , Yamamoto Takehito , Okamoto Koh , Tatsuno Keita , Ikeda Mahoko , Tanaka Takehiro , Wakabayashi Yoshitaka , Sato Tomoaki , Okugawa Shu , Moriya Kyoji , Suzuki Hiroshi
Published: July 2022

Prospective audit and feedback (PAF) is considered an effective procedure for appropriate antibiotic use. However, its effect on the time to de-escalation is unclear. We aimed to evaluate the effect of daily PAF implementation, focusing on the time to de-escalation of anti-methicillin‐resistant Staphylococcus aureus (MRSA) agents as an outcome measure. To this end, a single-center, retrospective, quasi-experimental study including patients treated with intravenous anti-MRSA agents during pre-PAF (April 1, 2014 to March 31, 2015) and post-PAF (April 1, 2015 to March 31, 2016) periods was conducted. The time to de-escalation was estimated using the Kaplan–Meier method, and Cox proportional hazard analysis was performed to assess the effect of daily PAF implementation on the time to de-escalation. Interrupted time series analysis was used to evaluate the relationship between daily PAF implementation and anti-MRSA agent utilization data converted to defined daily dose (DDD) and days of therapy (DOT) per 1,000 patient days. The median time to de-escalation was significantly shorter in the post-PAF period than in the pre-PAF period (6 days vs. 7 days, P < 0.001). According to multivariate analysis, PAF implementation was independently associated with a shorter time to de-escalation (hazard ratio [HR], 1.18; 95% confidence interval [CI], 1.02 to 1.35). There were no significant differences in hospital mortality, 30-day mortality, and length of stay between the two periods. Interrupted time series analysis showed significant reductions in the trends of DDD (trend change, –0.65; 95% CI, –1.20 to –0.11) and DOT (trend change, –0.74; 95% CI, –1.33 to –0.15) between the pre-PAF and post-PAF periods. Daily PAF implementation for patients treated with intravenous anti-MRSA agents led to a shorter time to de-escalation and lower consumption of anti-MRSA agents without worsening the clinically important outcomes.
Antimicrobial agents for the treatment of enteric fever chronic carriage: A systematic review
Authors: McCann Naina , Scott Peter , Parry Christopher M. , Brown Michael
Published: July 2022

Background

Chronic carriage of S. Typhi or S. Paratyphi is an important source of enteric fever transmission. Existing guidance and treatment options for this condition are limited. This systematic review aims to assess the evidence concerning the efficacy of different antimicrobials in treating enteric fever chronic carriage.

Methods

We searched major bibliographic databases using relevant keywords between 1946 and September 2021. We included all interventional studies that included patients with confirmed enteric fever chronic carriage and deployed an antimicrobial that remains in clinical practice today. Case reports and case series of under 10 patients were excluded. Two reviewers screened abstracts, selected articles for final inclusion and quality-assessed the included studies for risk of bias. Extracted data was analysed, with pooling of data and eradication rates for each antimicrobial calculated. As only one randomised controlled trial was identified, no meta-analysis was performed.

Results

Of the 593 papers identified by the initial search, a total of eight studies met the inclusion criteria and were included in the systematic review. Evidence was identified for the use of fluoroquinolones and amoxicillin/ampicillin in the treatment for enteric fever chronic carriage. Fluoroquinolones were superior to amoxicillin/ampicillin with 92% of patients achieving eradication after one antimicrobial course compared to 68% (p = 0.02). The quality of included studies was poor, and all were carried out before 1990.

Conclusion

This review identified fluoroquinolones and amoxicillin/ampicillin as treatment options for enteric fever chronic carriage, with fluoroquinolones the more effective option. However, this evidence pre-dates rises in antimicrobial resistance in enteric fever and therefore the significance of these findings to today’s practice is unclear. Further research is needed to investigate whether these antimicrobials remain appropriate treatment options or whether alternative interventions are more effective.
The evolution and co-evolution of a primary care cancer research network: From academic social connection to research collaboration
Authors: Vermond Debbie , de Groot Esther , Sills Valerie A. , Lyratzopoulos Georgios , Walter Fiona M. , de Wit Niek J. , Rubin Greg
Published: July 2022

Academic networks are expected to enhance scientific collaboration and thereby increase research outputs. However, little is known about whether and how the initial steps of getting to know other researchers translates into effective collaborations. In this paper, we investigate the evolution and co-evolution of an academic social network and a collaborative research network (using co-authorship as a proxy measure of the latter), and simultaneously examine the effect of individual researcher characteristics (e.g. gender, seniority or workplace) on their evolving relationships. We used longitudinal data from an international network in primary care cancer research: the CanTest Collaborative (CanTest). Surveys were distributed amongst CanTest researchers to map who knows who (the ‘academic social network’). Co-authorship relations were derived from Scopus (the ‘collaborative network’). Stochastic actor-oriented models were employed to investigate the evolution and co-evolution of both networks. Visualizing the development of the CanTest network revealed that researchers within CanTest get to know each other quickly and also start collaborating over time (evolution of the academic social network and collaborative network respectively). Results point to a stable and solid academic social network that is particularly encouraging towards more junior researchers; yet differing for male and female researchers (the effect of individual researcher characteristics). Moreover, although the academic social network and the research collaborations do not grow at the same pace, the benefit of creating academic social relationships to stimulate effective research collaboration is clearly demonstrated (co-evolution of both networks).
Determining factors of participation and success rates in research funding competitions: Case study
Authors: Rusu Valentina Diana , Mocanu Mihaela , Bibiri Anca-Diana
Published: July 2022

Research and innovation play a key role in generating smart and sustainable economic growth. By producing new knowledge, the research contributes to the development of new and innovative products, processes, and services, which in turn lead to increased productivity, industrial competitiveness, and, ultimately, the prosperity of the community as a whole. However, all research, development and innovation activities depend on the financial resources made available, as specific financing accelerates the production and dissemination of the best ideas and practices, as well as their role in meeting the challenges our society deals with nowadays. Our study aims to identify the determining factors for the researcher’s participation and success rates in research funding competitions. The goal of the research is to understand how variables such as age, gender, main field, affiliation, and scientific rank can affect the access to funding opportunities available for research and innovation. The study relies on a questionnaire-based survey conducted with 243 early-career and senior researchers from many state universities across Romania. For an in-depth analysis of the factors that influence the success rate in research competitions, in the present approach, we used both graphical and econometric methods. A binary logistic regression modelling was performed in order to explain the relationships between variables. Among other considerations, our findings revealed that in all main research fields, scientific rank and gender are important features for raising the participation and success rate in research funding competitions.
Dancing into a critical process drama
Authors: Coleman Claire
Published: July 2022

This article describes the critical process drama framework and highlights its potential to disrupt the status quo through an agenda of exploration and wonder. Generated through arts-based research exploring process drama as an enactment of critical pedagogy, the cumulative case study drew upon a document analysis of Cecily O’Neill’s Seal Wife workshop and exploration of the ‘mantle of the expert’ dramatic inquiry form. Developed to enact critical process drama, six key concepts – hope, aesthetic, agency, agitation, action and ambiguity – operate as an interwoven and reflexive framework to inform drama practice. Dynamic, relational and essential, these six concepts enact the theories of critical pedagogy and process drama as dialectical, improvisational approaches committed to transformation and social justice. As educators and artists, we cannot dance forever in the imagination or plod along hopelessly in reality. Through critical process drama participants, can operate critically in new worlds and significantly between worlds. We need to travel between and transform through transitions. In the crack between the light and dark we can dance and dance and dance.
Heterotopías temporales. Resignificar Madrid en la modernidad líquida
Authors: Llorente Sanz Jaime
Published: July 2022

Foucault nos dijo que cada cultura y sociedad constituye sus propias heterotopías, y estas son características y definen a la sociedad que las hace aparecer. ¿Es posible en la actualidad hablar de heterotopías, es un concepto vigente y aplicable, en última estancia útil? ¿Existe una o unas heterotopías que definan y caractericen a la sociedad actual que vive la modernidad líquida? El presente texto propone las heterotopías temporales como esas heterotopías características de la sociedad que vive en la modernidad líquida. Para intentar demostrar lo y definirlas se van a estudiar y analizar seis heterotopías temporales que han sucedido y siguen sucediendo, en algunos casos, en la metrópolis de Madrid. A partir de estos casos de estudio y la propuesta heterotópica intentaremos entender como la sociedad actual tiene una nueva relación con esa estructura urbana heredada que es la ciudad. Al analizar a la sociedad actual desde el punto de vista de las heterotopías temporales podemos establecer que la ciudad es un complejo puzle dinámico y en constante transformación. Más allá de las nuevas construcciones, rehabilitaciones y ensanches de la ciudad, este puzle apunta a cómo los individuos, con sus cuerpos, se relacionan con otros cuerpos y con la ciudad. Lugares de exclusión, de protesta, de ejercicio, de residencia, de identidad y muchos otros son los que significan la ciudad. Lugares heterotópicos que ya no solo dependen del lugar en sí para ser heterotopías sino de la relación entre individuos y grupos de ellos. Y estas relaciones están marcadas por las características y retos que plantea la modernidad líquida.
Problemas de cultura material: Fíbulas Itálicas y Griegas en la Península Ibérica entre s. VII-VI a. C.
Authors: Graells i Fabregat Raimon
Published: July 2022

Se presenta una revisión sobre cuarenta fíbulas de procedencia mediterránea recuperadas o conocidas como de procedencia peninsular. El trabajo examina de manera crítica ejemplares distribuidos por prácticamente todo el territorio peninsular valorando la falta general de contextos y la diacronía de los modelos. Para ello se relacionan tanto la tipología como el estado de conservación y las dinámicas de interacción culturales conocidas para cada contexto o supuesto contexto. Los tipos griegos están representados por un único ejemplar, los tipos centro- y noritálicos aparecen dispersos por el litoral mientras que tipos de la Italia septentrional se documentan en el interior peninsular. Tipos suritálicos o modelos fechados en cronologías anteriores a mediados del s. VII a. C. son problemáticos. El trabajo es una continuación del que afrontaba el mismo tema para el Golfo de León y, como en ese caso, el repertorio de ejemplares de segura procedencia peninsular es muy limitado siendo frecuente la presencia de piezas atribuidas a yacimientos o zonas incoherentes con el registro arqueológico y las dinámicas de las interacciones culturales antiguas.
Gender variation in whole genome sequencing of susceptibility genes in a rat model of depression
Authors: Jimoh-Abdulghaffaar Hidaayah , Joel Ireoluwa , Jimoh Olanrewaju , Ojulari Lekan , Ganiyu Kaosara , Alatiba Temidayo , Ogunyomi Victory , Awoliyi Victoria , Adebayo Muhammed , Agaka Adamah , Oyedeji Aminat , Kolade Ifeoluwa
Published: July 2022

Depression is one of the most common mood disorders among psychiatric diseases, affecting about 10% of the adult population. Animal models are used to aid the understanding of its pathogenesis and search for therapies. Some of the models of stress generate animals that are susceptible to stress while others are resilient. Thus, this study aimed to determine the similarities and/or differences in the genes responsible for susceptibility to chronic unpredictable stress (CUS)-induced depression-like behaviors in male and female Wistar rats. Sixty (30 male and 30 female) Wistar rats weighing between 120 & 150g were used for this study. The rats were randomly divided into two main groups: A (male) and B (female). Rats in each main group were further divided into control (10) and test groups (20). Rats in the test groups were subjected to CUS (Willner, 2017). Depression-like behaviors were assessed using a battery of behavioral tests. Rats in the CUS-susceptible group were sacrificed and the hippocampus excised. gDNAwasextracted from the hippocampal samples and purified. Purified DNA was subjected to whole genome sequencing (WGS). Base-calling of sequence reads from raw sequencing signal(FAST5) files was carried outand variants were called from alignment BAM files.Genes were identified, their impacts estimated, and variants annotated.60% of each of the male and female rats subjected to CUS showed significant (p<0.05) depression-like behaviors. WGS of the hippocampal DNA revealed atotal of 289,839 SNPsvariant types,7002insertions,34,459 deletions, and 1,570,186 single nucleotide polymorphisms(SNPs)variant types, 109,860insertions, 597,241 deletionsin CUS-susceptible male and female Wistar rats respectively.A total of 6 and 22 genes are implicated in increased susceptibility to depression in male and female Wistar rats respectively (M: F = 1:3.7).
Brahmagupta and the concept of Zero
Authors: Feliksiak Monica
Published: July 2022

This paper attempts to reconstruct the possible reasoning process that led the great Indian mathematician Brahmagupta in 628 A.D. to the formulation of two controversial rules for arithmetic, involving the number zero; rules which contradict modern arithmetic principles. Is it possible to explain these rules in some logical manner? This paper outlines a possible explanation of the issue based on similar reasoning. One may ask, why is the concept of zero so important? “From counting to calculating, from estimating the odds to knowing exactly . . . all of their parts swing on the smallest of pivots, zero” Kaplan [12]. Today’s technology would simply be impossible, from the smallest electronic device to space technology, engineering, mathematics and physics. If it were possible to erase the existence of zero from the annals of human achievement, we would be thrown back into the ancient times. Humanity owes a great debt of gratitude to the original inventor of zero - Brahmagupta, as well as to the Indian culture.
Credit Card Fraud Detection Techniques: A Survey
Authors: Ahmed Muhammad Hazeel
Published: July 2022

Fraud events are increasing on day to day bases. Credit card fraud is the most frequent fraud that is making a big financial loss on a global level. Researchers have implemented many machine learning algorithms to detect the credit card frauds. This research has briefly described several algorithms and compares the performance of Random Forest, Naïve Bayes, K-Nearest Neighbor, Logistic Regression and Multilayer Perceptron. Algorithms are also used to classify the real transactions or fraudulent transactions. These datasets are compared on the basis of accuracy, precision, recall & false positive rate. Comparison results show that Random Forest performs best in credit card fraud detection dataset among others. Research shows that any ML algorithm can be used to demonstrate the classification of fraud detection.
An Assessment of the Potential Value for Climate Remediation of Ocean Calcifiers in Sequestration of Atmospheric Carbon
Authors: Moore David , Heilweck Matthias , Fears M.D. William Burton , Petros Peter , Squires Samuel James , Tamburini Elena , Waldron, Jr. Robert Paul
Published: July 2022

Today’s marine calcifiers (coccolithophore algae, Foraminifera [protists], Mollusca, Crustacea, Anthozoa [corals], Echinodermata) remove carbon dioxide (CO
2) from the atmosphere, converting it into solid calcium carbonate (CaCO
3) which is stable for geological periods of time. These organisms could serve as a biotechnological carbon capture and storage mechanism to control climate change. Two criticisms made about this are: (i) ocean acidification has allegedly been shown to cause reduced shell formation in calcifiers; (ii) the calcification reaction that precipitates CaCO
3 crystals into the shells is alleged to return CO
2 to the atmosphere. In this review we assess the evidence concerning such criticisms and find reasons to doubt both. Experiments showing that ocean acidification is damaging to calcifiers have all used experimental pH levels that are not projected to be reached in the oceans until the next century or later; today’s oceans, despite recent changes, are alkaline in pH. Claiming precipitation of CaCO
3 during calcification as a net source of CO
2 to the atmosphere is an oversimplification of ocean chemistry that is true only in open water environments. Living calcifiers do not carry out the calcification reaction in an open water environment in equilibrium with the atmosphere. The chemistry that we know as life takes place on the surfaces of enzymatic polypeptides, within organelles that have phospholipid membranes, contained in a cell enclosed within another phospholipid bilayer membrane specifically to isolate the chemistry of life from the open water environment. Ignoring what is known about the biology, physiology, and molecular cell biology of living organisms, calcifiers of all types especially, leads to erroneous conclusions and deficient advice about the potential for calcifier biotechnology to contribute to atmosphere remediation. Net removal of CO
2 from the atmosphere by calcifiers is only achieved by the CaCO
3 stored in the shell, coccoliths, or foram tests that are left when they die. To capitalise on this requires a change in paradigm towards cultivating calcifiers for their CaCO
3 rather than their meat or other products. We conclude that the world’s aquaculture industries already operate the biotechnology that, with massive and
immediate global expansion, can contribute to sustainably controlling atmospheric CO
2 levels at reasonable cost and with several positive benefits in addition to carbon sequestration.
HABILIDADES METALINGUÍSTICAS E USO DE LÍNGUA NAS PROPOSIÇÕES DE QUATRO CURRÍCULOS DE LÍNGUA BRASILEIRA DE SINAIS
Authors: Venâncio Barbosa Felipe
Published: July 2022

Este trabalho apresenta uma descrição de aspectos gerais de quatro currículos de Libras elaborados por municípios do estado do Rio Grande do Sul e do estado de São Paulo: Rio Grande, Canoas, Guarulhos e São Paulo. São apresentadas as proposições para a Libras nestes documentos e feita uma análise de como elas abordam as habilidades metalinguísticas e o uso da língua. Os documentos analisados refletem uma direção apontada pelos estudos surdos e pelos estudos linguísticos atuais com relação ao aprofundamento dos objetivos de ensino de línguas de sinais como primeira língua. A relação entre objetivos de aprendizagem e desenvolvimento voltados ao uso e à metalinguagem revelou preponderância daqueles voltados às habilidades metalinguísticas em dois dos documentos. As peculiaridades desses quatro documentos os tornam diferentes, mas em consonância com a BNCC ao realizarem suas proposições de acordo com suas realidades locais sem deixar de lado as orientações do documento federal e o estado da arte na área.
A LIBRAS NA LEI E NA PRÁTICA ESCOLAR
Authors: Fernandes Cristiane Lima Terra
Published: July 2022

No Brasil, a Língua Brasileira de Sinais – Libras é reconhecida como língua da comunidade surda brasileira, desde 2002, o que possibilitou avanços, principalmente na área da educação. Timidamente, a Libras vem sendo divulgada nos espaços sociais e na mídia. Porém, ainda faltam profissionais capacitados para atuar não apenas na área da educação de estudantes surdos, mas nos mais variados ambientes sociais, nos quais as pessoas surdas circulam e necessitam de comunicação acessível. O objetivo deste artigo é apresentar em qual panorama legal a Libras está inserida e como ela acontece na prática escolar, explicitando o que temos e o que ainda falta para alcançar o que, de fato, precisamos. Há escolas bilíngues criadas no País, em número muito inferior ao que é necessário. Dentre a maioria das escolas bilíngues não há um currículo de Libras como primeira língua sendo praticado. A maioria delas segue o modelo de ensino de Libras para ouvintes, ou seja, segunda língua, ou focam ensino de questões culturais do povo surdo, pouco enfatizando o ensino das questões linguísticas e gramaticais da língua. Considera-se que tais ações se devem ainda aos reduzidos espaços de debates sobre o ensino formal da Libras como primeira língua e, também, pela escassez de formação de professores de Libras nesse viés.
ALFABETIZAÇÃO NA LÍNGUA DE SINAIS NO CURRÍCULO DE LÍNGUA DE SINAIS
Authors: Mertzani Maria
Published: July 2022

O desenvolvimento de currículos de línguas de sinais é um acontecimento contemporâneo que poucos países puderam implementar oficialmente para ensinar a Língua de Sinais padrão nacional como primeira língua (L1) e/ou língua materna nas séries escolares. Nestes, a Língua de Sinais figura como uma disciplina obrigatória, que a criança surda precisa estudar e se desenvolver metalinguisticamente, como é o caso do aprendizado de línguas faladas como L1. Uma língua de sinais como metalinguagem também significa que o currículo ensina conhecimentos linguísticos explícitos para que a criança compreenda gradualmente como a língua de sinais funciona em diferentes contextos, para que faça escolhas efetivas de significado ou estilo e para que compreenda os conteúdos de forma mais completa ao estudar a língua. Em outras palavras, o currículo de língua de sinais aborda a importância de desenvolver a alfabetização na língua de sinais para a criança. Tradicionalmente, a alfabetização está ligada à leitura e à escrita e, para sua aprendizagem, o currículo de línguas estabelece cinco componentes essenciais da alfabetização inicial: compreensão, consciência fonológica, fonética, conhecimento de convenções de escrita e fluência. O artigo discute esses componentes em apoio à alfabetização na língua de sinais como uma forma de alfabetização verbal (não escrita), a partir de um estudo documental entre o currículo da língua de sinais e o currículo indígena.
SIGNS OF LEARNING
Authors: Carty Breda , Bontempo Karen , Beuzeville Louise de
Published: July 2022

Australia’s education system has historically been premised on state and territory-based curricula, until the development of a national curriculum in each learning area, released in stages from 2014. This paper will discuss the curriculum development process for the Auslan curriculum in the Languages learning area, which delivered an endorsed blueprint for the formal teaching and learning of Auslan in Australian schools from 2017. Unique features of the curriculum will be outlined, such as the dual-pathways for first and second language learners of Auslan, and the different sequence entry points, specifically designed to meet the needs of deaf children in both the early primary school years, as well as those who are late learners of a first language, entering secondary school with limited spoken and/or signed language later in childhood. The paper will provide an overview of the structure and content of the curriculum and the nature of the learners, and conclude with some of the opportunities and challenges arising from this initiative, such as the ongoing lack of quality resources that exist for its day-to-day implementation in schools nation-wide.
SIGN LANGUAGE LITERACY IN THE SIGN LANGUAGE CURRICULUM
Authors: Mertzani Maria
Published: July 2022

The Sign Language curriculum is a contemporary development which few countries have officially implemented to teach a national standard Sign Language as a first language (L1) and/or mother tongue in the school grades. In these, Sign Language is a mandatory unit, which the deaf child needs to study and develop metalinguistically, as is the case in learning spoken languages as L1. A Sign Language as a metalanguage also means that the curriculum teaches explicit linguistic knowledge for the child to understand gradually how SL functions in different contexts, to make effective choices for meaning or style, and to comprehend more fully when attending the language. In other words, the Sign Language curriculum addresses the importance of developing the child’s Sign Language literacy. Traditionally, literacy is linked to reading and writing and for its learning the language curriculum sets five essential early literacy components: comprehension, phonological awareness, phonics, print convention knowledge and fluency. The paper discusses these components in support of Sign Language literacy as a verbal (non-print) form of literacy, based on a documental study among the Sign Language and indigenous curriculum.
METALINGUISTIC SKILLS AND LANGUAGE USE IN THE PROPOSITIONS OF FOUR BRAZILIAN SIGN LANGUAGE CURRICULA
Authors: Barbosa Felipe Venâncio
Published: July 2022

This paper presents a description of the general aspects of four Libras curricula developed by the municipalities in the state of Rio Grande do Sul and the state of São Paulo - Rio Grande, Canoas, Guarulhos and São Paulo, in Brazil. The propositions for Libras are presented in these documents and an analysis is made of how they approach metalinguistic skills and language use. The analyzed documents reflect a direction pointed out by deaf studies and by current linguistic studies regarding the deepening of the objectives of teaching sign languages ​​as a first language. The relationship between the objectives of learning and development aiming at use and metalanguage revealed a preponderance of those focusing on metalinguistic skills in two of the documents. The peculiarities of these four documents make them different, though in line with the Brazilian Common National Curricular Base when carrying out their propositions according to their local realities without leaving aside the guidelines of the federal document and the state of the art in the area.
BILINGUAL CURRICULUM MATERIALS SUPPORTING SIGNED LANGUAGE AS A FIRST LANGUAGE FOR DEAF STUDENTS
Authors: Hoffmeister Robert J , Karipi Spyridoula , Kourbetis Vassilis
Published: July 2022

Considering Deaf children and adults as bilingual - their first language is a Signed Language (SL) and the second language is learned via print - provides professionals with a paradigm to be used for creating better learning opportunities. In this paper, Greek Sign Language ((G)SL)) [1] as a first language (L1) is the base language we use to present certain bilingual methodological teaching and learning considerations. This work is the result of a long journey from the initial thinking of the American Sign Language Curriculum and its influence on the development of the (G)SL curriculum in Greece. The paper offers discussion of innovative educational multimedia material that are easily accessed via online web portals, developed for teaching (G)SL as an L1 to pre-school and primary school Deaf children. In this work, SL as L1 is a resource that fully enables Deaf children to learn an L2 via print, supporting their bilingual acquisition capabilities. In developing curricula and supporting materials, we consider two important foundational components: Deaf native signers and near native signers as language role models for Deaf children, parents and teachers; and the development and interaction with digital educational materials. Thus, collaboration between educational and technology professionals and members of the Deaf community is critical. This bilingual model can be incorporated into any SL. (G)SL) is used as a model to display innovative practices merging SL (L1), print (L2), technology and creative instructional and assessment materials, maximized by understanding the visual nature of SL and its advantages for school learning. The penultimate goal is Deaf students to become successful bilingual learners to fully function in the world today and tomorrow.

 

 

[1] In this paper, we will use (G)SL to indicate that we are discussing Greek Signed Language but content and technology can be used for any SL.
LIBRAS IN LAW AND SCHOOL PRACTICE
Authors: Fernandes Cristiane Lima Terra
Published: July 2022

In Brazil, the Brazilian Sign Language – Libras has been recognized as the language of the Brazilian deaf community since 2002, a recognition that has allowed advances, especially in the area of education. Timidly, Libras has been publicized in social spaces and in the media. However, stilltrained professionals are lacking to work not only in the area of education of deaf students but in the most varied social environments where deaf people circulate and need accessible communication. This paper presents the legal context in which Libras is inserted and occurs in the school practice, explaining what we have and what is still missing to achieve. There are bilingual schools in the country though in lower numbers than it is actually needed. Moreover, among most bilingual schools, a Libras first language curriculum is not being practiced. Most of them follow the model of teaching Libras to hearing people as a second language, or focus on teaching cultural issues of the deaf people with little emphasis on teaching the linguistic and grammatical aspects of the language. Such actions are due to limited debates on the formal teaching of Libras as a first language as well as due to the scarce training of Libras teachers.
Yo llana estoy: Jerarquías, transgresiones y despliegues de género en América hispana colonial (1492–1898)
Authors: Silva Yamile , Burgos Ana María Díaz
Published: July 2022

Esta introducción al dossier temático sobre género y sexualidades en la América hispana colonial revisita los debates académicos recientes sobre estos temas a la vez que los pone en diálogo con los cinco ensayos que lo conforman. Estos ensayos examinan las transgresiones de género y sexualidades en territorios hispanoamericanos entre el siglo XVI y principios del siglo XIX teniendo en cuenta dos ángulos de análisis: los usos de la ley y los del cuerpo. Complementan este dossier dos entrevistas a autoras latinoamericanas que demuestran la extensión de estos temas coloniales a los campos de la producción literaria contemporánea.
Bailadoras: Las mujeres y el fandango en España y la Nueva España del siglo XVIII
Authors: Deanda-Camacho Elena
Published: July 2022

Este ensayo analiza las descripciones que viajeros y clérigos hicieron de las bailadoras de fandango en España y la Nueva España en el siglo XVIII. El fandango fue tanto un baile español como un tipo de fiesta popular novohispana. En esta época, ambos manifestaron “dramas sociales”–siguiendo a Víctor Turner—en los cuales grupos hegemónicos y clases bajas se enfrentaron. Viajeros y clérigos condensaron esos “dramas” en la descripción del cuerpo de la bailadora, quien apareció erotizada o exotizada. En los intersticios de sus descripciones, elucido vestigios de la práctica estética de la bailadora y cómo simultáneamente ella creó comunidad a la par que afirmaba su individualidad.
Anarquismo y naturalismo en la obra temprana de Salvadora Medina Onrubia
Authors: Carballo Alejandra Karina
Published: July 2022

La obra temprana de Salvadora Medina Onrubia testimonia demandas sociales emergentes a principios del siglo XX que el anarquismo hacía en nombre de los desclasados y oprimidos. Basado en un discurso anarco-positivista, Medina Onrubia denuncia arbitrarias e inhumanas condiciones de trabajo y de vivienda, además de la inequidad salarial y legal que afectaban tanto a la familia rural como a la proletaria bajo los mismos opresores: el Estado y la élite gobernante. Temas tales como el de la tuberculosis y el alcoholismo, así como el trabajo y la independencia femeninos son tratados en su obra en términos biologizantes y de género.
COVID-19 & informal settlements: is ‘Stay Home’ safe?
Authors: Nix Emily , Paulose Jacob , Lakhanpaul Monica , Factor-Litvak Pam , Parikh Priti , Altamirano-Medina Hector , Bou Karim Yasmin , Manikam Logan ,   on behalf of the CHIP Consortium
Published: July 2022

The disproportional burden of coronavirus (COVID-19) and vulnerability to containment measures in informal settlements have been recognised; however, the role of poor housing conditions in propagating these remains neglected. Poor housing conditions makes it difficult to effectively implement social distancing measures. With increased time spent in cramped, dark and uncomfortable indoor environments, water and sanitation outside the home, and no outdoor space, higher exposure to existing health hazards and high levels of stress, with women and children being most vulnerable, are anticipated. Through this commentary paper, we reflect on these interconnections and recommend immediate measures and the long-term need for adequate housing for health and well-being.
Dulcinéia Catadora
Authors: Borghi Paula
Published: July 2022

Arte como afeto de transformações sociais; esta é a ideia que rege a entrevista com a artista Lucia Rosa, uma das idealizadoras do coletivo Dulcineia Catadora. Este artigo busca contar como este projeto de arte atua tanto macropoliticamente como micropoliticamente na potencialização da vida, em combate à subjetividade colonial e neoliberal. Uma entrevista realizada durante um momento em que o genocídio político e sanitário regiam o país.
Espectros de um não lugar
Authors: Koch Karina
Published: July 2022

Espectros de um não lugar é um ensaio visual composto de 8 imagens que aborda as relações entre indivíduos e a cidade a partir do conceito de não lugar proposto pelo antropólogo francês Marc Augé. Este ensaio utiliza a técnica da fotografia pinhole como instrumento de percepção das relações sociais no espaço urbano, uma forma de revelar um olhar sensível sobre a cidade em meio a uma sociedade imersa em deslocamentos cada vez mais velozes e espaços cada vez menos relacionais – os não lugares. Pelas características de sua feitura, por ser um processo fotográfico artesanal, a fotografia pinhole suscita vínculos entre o fotógrafo e o espaço fotografado, justamente problematizando a questão destes espaços que não sugerem vínculos – estações de trem e de ônibus, ruas movimentadas, aeroportos etc.
Porto Fluvial RecHouse
Authors: Careri Francesco , Bernardini Aurora
Published: July 2022

Trata-se da descrição da proposta do projeto Porto Fluvial RecHouse, de regeneração de um edifício na via Porto Fluviale, na ex-zona industrial de Roma. No projeto colaboraram entidades municipais, universitárias, governamentais e populares (os antigos moradores da zona).Entre os objetivos de refuncionalização propostos e aprovados estão: reduzir o problema habitacional com um processo de integração social e de uma ocupação habitacional; dotar o bairro de um novo espaço público; utilizar modalidades inovativas de gestão; ativar um processo de participação; incrementar a mixité social entendida como antídoto contra os processos de gentrificação em ato no bairro; valorizar a proximidade social entre grupos heterogêneos.
Aportaciones desde el Geoforo a una ciudadanía crítica
Authors: Monteagudo Diego García , González Xosé Manuel Souto
Published: July 2022

La crisis sanitaria en la COVID-19 condicionó un escenario de preocupación por el enfrentamiento político entre posiciones sociales; los que quieren mantener sus privilegios y los que simplemente quieren sobrevivir. En este artículo queremos ofrecer un argumento a favor de la racionalidad del sistema escolar para construir un discurso educativo que facilite la comunicación entre personas de diferentes lugares, con el objetivo de crear conexiones de pensamiento crítico. La creación del Geoforo en 2008 facilitó el intercambio de pensamientos, hechos y reflexiones sobre el compromiso personal y grupal en relación a la implicación de la geografía, y otras ciencias sociales, en la elaboración de una interpretación de los problemas ambientales y sociales. El rol del docente como intelectual que busca incidir en la participación escolar es el eje que articula nuestro aportación.
Aprendendo sobre a cidade: o ensino por argumentação e a construção de um conhecimento geográfico poderoso
Authors: Castellar Sonia Maria Vanzella , Souza Livia Reis Dantas de
Published: July 2022

Este artigo explora uma prática investigativa realizada por meio de uma sequência didática que abordou o ensino por argumentação e os conceitos de território e cidade com alunos de Geografia dos anos finais do Ensino Fundamental na cidade de Cubatão-SP. Partindo da recontextualização dos conceitos de território e cidade, a proposta metodológica selecionada estimulou os alunos a produzirem argumentações sobre os problemas urbanos e as consequências dos modos de produzir e viver na cidade. A análise dos dados coletados aponta para a mudança conceitual dos estudantes, bem como a presença de elementos de raciocínio geográfico nos argumentos produzidos pelos alunos. Interpretamos que planejar os aspectos curriculares e pedagógicos das práticas escolares é uma forma de promover um conhecimento poderoso no campo da Geografia escolar.
Programa de Educação Tutorial e OBMEP na escola: influências na formação inicial de futuros professores de matemática
Authors: Peixoto Rafael , Cintra Vanessa de Paula , Paulin Juliana França Viol
Published: July 2022

Neste artigo analisamos aspectos relevantes sobre a formação inicial  de alunos do curso de Matemática de uma Universidade Pública que participaram do Programa de Educação Tutorial (PET), no projeto de extensão intitulado “PET Matemática na OBMEP na escola”, que envolve ações desenvolvidas pelos participantes junto à Olimpíada Brasileira de Matemática das Escolas Públicas (OBMEP). Trata-se de uma pesquisa qualitativa e os dados foram coletados por meio de questionários respondidos pelos participantes do projeto e analisados segundo a Análise de Conteúdo. Com a análise dos dados, pudemos identificar que as vivências dos futuros professores de Matemática na escola, possibilitadas pelo projeto conjunto entre o PET e a OBMEP, podem ser caracterizadas como uma oportunidade de construção do conhecimento matemático para o ensino e do conhecimento da prática, gerada pelo terceiro espaço de formação.
MAPEAMENTO DA DIFUSÃO DA COVID-19 EM SANTA CATARINA - DISSEMINAÇÃO DA DOENÇA NAS REGIÕES INDUSTRIAIS DO ESTADO
Authors: Fleig Raquel , Do Nascimento Iramar Baptistella , De Oliveira Francisco Henrique , Valdati Jairo
Published: July 2022

Objetivo: Identificar fatores sociais e econômicos que favoreceram a dissiminação da COVID-19 para as regiões industriais do estado de Santa Catarina, Brasil. Métodos: A pesquisa foi bibliográfica e documental, em três etapas metodológicas: as características sociais e econômicas das diferentes regiões geográficas; levantamento e representação gráfica do número de casos ativos de COVID-19 gerados pelo Laboratório de Geoprocessamento da Universidade do Estado de Santa Catarina; e análise das possíveis relações sobre a dinâmica cotidiana da população industrial e sua compatibilidade junto ao mapeamento quanto ao número de casos ativos de COVID-19. Resultados: A variabilidade do contato de novas cepas da COVID-19 tem forte convergência com as mobilizações turísticas e aspectos econômicos urbanos do trabalhador industrial. Deve-se considerar, para as populações industriais, os coeficientes de inter-relações que favoreçam o contágio, como as centralizações, os distanciamentos, as moradias e a necessidade de mobilidade pelo transporte público. Conclusões: A criação de políticas públicas com medidas de acordo com as demandas locais, percebendo cada perfil comportamental, é fundamental, uma vez que a abordagem regional específica das regiões pode mitigar o contágio da COVID 19. Sugere-se a reorganização e mapeamento das conexões cotidianas entre localizações e distanciamentos das respectivas moradias de funcionários e seus vínculos empregatícios.
Contribuições de Red Flags para Detecção de Fraudes Corporativas
Authors: Ramos do Nascimento Monize , Rech Ilírio José
Published: July 2022

O objetivo desta pesquisa foi investigar as contribuições dos red flags obtidos de relatórios financeiros na detecção de fraudes corporativas. Foram selecionadas 277 companhias abertas não financeiras listadas na B3 (Brasil Bolsa Balcão) com dados do período de 2006 a 2018. Os dados e informações foram coletados nas notas explicativas das empresas, na base Refinitiv®, no site da Comissão de Valores Monetários (CVM) e da Polícia Federal. Com base na Regressão Logística para dados em painel, foram analisadas as variáveis firma de auditoria, crescimento dos estoques, representatividade dos passivos, rentabilidade e perdas operacionais. As variáveis foram selecionadas tendo em vista sua relevância identificada na literatura como detentoras de potencial para identificar riscos de fraudes. Os resultados demonstraram que os red flags firma de auditoria e o endividamento mensurado pela ponderação dos passivos pelos ativos totais contribuem para a identificação do risco de fraudes corporativas. O estudo contribui para analistas, credores e investidores identificarem, com base nos red flags, empresas com risco de fraudes corporativas. A fraude corporativa é um crime que afeta todas as empresas e o estudo de red flags é relevante para investidores e analistas identificarem empresas com indícios de fraudes ou no caso de a gestão identificar estas no seu estágio inicial. Os resultados do estudo podem influenciar o trabalho de auditores internos e externos, organismos fiscalizadores, investidores, analistas, agências de classificação de crédito e sistema bancário.