bluuebunny/crossref_metadata_2025 huggingface dataset:
Asset Evaluation Utilizing Multi-Variate Statistics Integrating Data-Mining, Completion Optimization, and Geology Focused on Multi-Bench Shale Plays
Authors: Gaurav Abhishek , Gibbon Edward J. , Roberson Timothy M.
Published: February 2017

The objective is to establish a robust methodology for evaluating the true economic potential of an asset integrating various sources of data, namely, geological, completions, production and leasing data retrieved from public sources.

A three segment methodology has been adopted in assessing properties for acquisition or farmout opportunities. The central idea of the work is that completions optimization is an ever-changing process. This implies the areas that were previously overlooked could potentially benefit from recent advances in completions and be more profitable. Data mining integrated with available geological information assists in identifying the key parameters that affect well performance. Once optimized for completions parameters, one can identify the real potential of an asset under consideration.

When geological factors, completions parameters, normalized production type curves, cost of drilling, completions and leasing are taken into account, we reach an even ground comparing different assets. Using this methodology, opportunities were identified in different areas that were previously overlooked. Some of the geological factors that should always be taken into account are depth (TVD), reservoir pressure, existing PVT/GOR studies, and prior knowledge of faults/fractures. The completions parameters that influence production have a wide range. However, it is reasonable to assume that length of lateral, stage spacing, type of fluid, proppant amount, rate of pumping and clusters per stage are the more important ones. The proppant amount, fluid type and rate of pumping can be inter-dependent. In areas with a significant number of horizontal wells on production, data on completions, geology and production is usually available on Public Sources, like the Texas Railroad Commission. The aggregation of data on several wells feeds into the creation of a huge data-set, in other words, big data. Once a combination of above mentioned factors is taken into account, the pattern identification process related to correlation of performance vs. parameters is quickly established. The type curve which corresponds to the optimum parameters for the particular area of interest, is then used for economic forecasting.

This paper truly integrates various factors that go into investment decision making. The advances in data visualization tools and the availability of big data from public sources assist in solidifying this robust methodology. The methodology described can be utilized by E&P companies, investment banks and private equity groups to make well informed investment decisions in the future.
Depth-of-Investigation and Volume-of-Investigation Calculated from Fracture-Injection/Falloff Test DFIT Data
Authors: Jackson Robert A. , Craig David P.
Published: February 2017

Unconventional reservoirs, including shale formations and many tight-gas sands, contain natural fractures, fissures, faults, and microfractures that contribute to the rock flow capacity. In most cases, core-measured permeability, and especially crushed-core permeability measurements, may not be representative of the true reservoir rock flow capacity. Evaluating the in-situ rock permeability, and simulating production, requires sampling not only the matrix, but also the fractures and fissures that contribute to the unconventional rock system permeability. A properly designed well test in an unconventional reservoir will sample a volume of reservoir rock that is representative of the whole. In other words, a well test should sample a representative elementary volume, which is the smallest volume of rock with properties characteristic of the whole.

Diagnostic fracture-injection/falloff tests (DFIT) have been routinely implemented since the late 1990s to understand leakoff mechanisms, identify fracture closure stress, estimate initial reservoir pressure, and determine permeability-thickness in unconventional reservoirs. In almost every unconventional well completed, a DFIT is the only well test that will be completed during the well lifecycle, but historically, the tests have been designed empirically based on analog formations and without considering the volume of rock investigated.

We demonstrate a new method for calculating the volume of rock investigated by a DFIT, and we show how a DFIT design can allow for sampling a representative elementary volume of the reservoir.
Enhance Microscopic Sweep Efficiency by Smart Water in Tight and Very Tight Oil Reservoirs
Authors: Kadeethum T. , Sarma H. K. , Maini B. B.
Published: February 2017

In the literature, improvement of oil recovery in smart water injection schemes has been shown to be mediated by wettability alteration. This process reduces residual oil saturation, which in turn affects the microscopic sweep efficiency and leads to subsequent enhancement of overall waterflood performance (Willhite, 1986). Tight and very tight oil reservoirs are often associated with high clay content and significant Cation Exchange Capacity (CEC) values (Breeuwsma et al., 1986). CEC directly influences smart waterflood behavior as it controls ion exchangeability between the solid and aqueous phases, which then regulates the double layer thickness and the wettability of the system (Nasralla and Nasr-El-Din, 2014).

This study presents the effect of lithology on CEC value. Experimental studies on smart waterflooding in tight oil cores have reported reduction of residual oil saturation by as high as five percent and improvement of microscopic sweep efficiency by six percent (Xie et al., 2015a, 2015b). The promising potential of smart water in tight and very tight oil reservoirs is similarly shown in numerical simulations, in which oil recovery is improved by three percent. Smart water may additionally retard water production by reducing water relative permeability. Furthermore, it enhances effective porosity/permeability through mineral dissolution. However, in tight oil reservoirs, pressure maintenance efficacy could be an issue. Simulation results display a significant pressure drop in the reservoir, which could lead to gas phase liberation and liquid relative permeability reduction.

Currently, few studies on smart waterflood in tight and very tight oil reservoirs exist. This work examines smart waterflood opportunities in these reservoirs from both an experimental and a numerical perspective.
Gas Selection for Huff-n-Puff EOR in Shale Oil Reservoirs Based upon Experimental and Numerical Study
Authors: Li Lei , Sheng James J. , Xu Jinze
Published: February 2017

Huff-n-Puff gas injection is a method originally used in heavy oil reservoir to reduce oil viscosity, increase mobility and displacement efficiency to enhance oil recovery. Now this method has been applied to enhance unconventional oil recovery in shale or tight reservoirs in recent years and proved to be effective in experiment study. N2, C1, CO2 or other rich gases are used in shale oil EOR. The purpose of this paper is to compare the EOR potential of different gas and provide a guide to choose gas based on the Wolfcamp shale oil reservoir.

The composition of crude oil from Wolfcamp was analyzed by Gas Chromatography (GC). First, the core plugs from Wolfcamp with diameters of 1.5 inches were saturated with crude oil. Then gas huff-n-puff experiments using N2, C1, and CO2 were conducted in the laboratory with the same injection pressure of 2000 psi. Based on laboratory results, a compositional model is built and used to analyze the performance of gas huff-n-puff. The EOR capacity of gas mixture (N2, C1, CO2) and some solvents such as C3-CO2 mixture, the separator gases C1 to C4 from the field production were investigated using the simulation method.

From the experiment results of the three kinds of gas injections, the oil recovery in the first two injection cycles were large. The incremental oil recovery decreased as the increase in number of injection cycles. Comparing the three kinds of gas EOR effects on Wolfcamp core samples, CO2 EOR result was the best, followed by N2 and C1. Coupling the equation of state method with GC analysis, 24 components of crude oil were achieved and then lumped into 5 pseudo components for simulation. The EOR effects of other gas mixture and solvents are investigated using the field model. The results show that the EOR effect of mixture of C1, C2 and C4 is the most favorite, followed by CO2-C3 mixture, produced gas, C1-CO2 mixture, and N2-CO2 mixture. Combined all of these results with economic factors, a comparison of gas capacity is proposed.

This investigation is focused on injection gas selection for shale oil production and helps to provide us a screening criterion to choose effective and convenient gas when conducting huff-n-puff gas injection in shale oil development. Cheaper gas with higher EOR potential will reduce the production cost and bring huge economic benefits to oil company especially in this low oil price period.
Parasitic Gregarine blattarum Found Infecting American Cockroaches, Periplaneta americana, in a Population in Pulau Pinang, Malaysia
Authors: Zary Shariman Yahaya  , Nik Ahmad Irwan Izzaudin  , Ainul Farhana Abdul Razak
Published: February 2017

A study on the prevalence of a common endoparasite in the wild population of the American cockroach was conducted in Penang Island using a trapping method at several sampling sites on the island. Gregarine blattarum was found in the digestive tract in 5 out of 115, or 4.35%, of the wild American cockroaches, Periplaneta americana, that were sampled. This is the first report in Malaysia of Gregarine blattarum in local American cockroaches.

 

Satu kajian ke atas prevalens endoparasit biasa dalam populasi Lipas Amerika liar di Pulau Pinang dilakukan dengan kaedah perangkap di beberapa kawasan pensampelan di pulau tersebut. Gregarine blattarum ditemui dalam saluran pencernaan 5 daripada 115, atau 4.35%, dari Lipas Amerika liar, Periplaneta americana yang disampel. Ini merupakan penemuan pertama Gregarine blattarum di dalam Lipas Amerika tempatan yang dilaporkan di Malaysia.
Prevalence of Muscular Sarcosporidiosis in Slaughtered Domestic Pigs in Perak, Peninsular Malaysia
Authors: Fazly Ann Zainalabidin  , Muhamad Syamsul Naim Noorazmi  , Wan Normaziah Wan Omar Bakri  , Geethamalar Sathaya  , Mohd Iswadi Ismail
Published: February 2017

Sarcosporidiosis is a disease caused by intracellular protozoan parasites, namely, Sarcocystis spp. In pigs, three species of Sarcocystis spp. have been recognised, including Sarcocystis meischeriana, Sarcocystis porcifelis and Sarcocystis suihominis. The aim of this study is to determine the prevalence of muscular sarcosporidiosis in pigs using the pepsin digestion technique. A total of 150 fresh heart, oesophagus and thigh muscle samples from 50 Yorkshire and Landrace pigs were collected from two local abattoirs in Perak from May to August 2014. All the fresh muscle samples were thoroughly examined for macrocyst-forming Sarcocystis spp. and processed using the peptic digestion technique to detect bradyzoites. The results from the muscle samples showed that 58% (29 out of 50) of the pigs were positive for Sarcocystis spp. These findings highlight the importance of implementing stringent measures for screening pigs in abattoirs for Sarcocystis spp. infection because this infection in pigs is a public health concern.

 

Sarkosporidiosis adalah penyakit yang disebabkan oleh parasit protozoa intraselular iaitu Sarcocystis spp. Pada khinzir, tiga spesis Sarcocystis spp. telah dikenalpasti antaranya Sarcocystis meischeriana, Sarcocystis porcifelis dan Sarcocystis suihominis. Tujuan kajian ini adalah untuk menentukan prevalens sarkosporidiosis otot pada khinzir dengan menggunakan teknik penghadaman peptik. Sebanyak 150 sampel segar otot jantung, esofagus dan paha daripada 50 khinzir jenis Yorkshire dan Landrace telah dikumpulkan dari dua buah tempat sembelihan tempatan di Perak mulai bulan Mei hingga Ogos 2014. Kesemua sampel segar tersebut diperiksa secara kasar untuk mengesan pembentukan-makrosis Sarcocystis spp. dan seterusnya diproses secara teknik penghadaman peptik bagi mengesan kehadiran bradizoit. Hasil yang diperolehi menunjukkan 58% (29 daripada 50) khinzir adalah positif terhadap Sarcocystis spp. Penemuan ini menggambarkan kepentingan untuk melaksanakan langkah-langkah yang ketat dalam pemeriksaan khinzir-khinzir di rumah sembelihan terhadap infeksi Sarcocystis spp. kerana kepentingannya terhadap kesihatan awam.
Rattan (Calamoideae) Diversity and Biomass Change in Different Habitat Types During Two Years
Authors: Nadine Ruppert  , Asyraf Mansor  , Shahrul Anuar Mohd Sah
Published: February 2017

Rattans (subfamily Calamoideae) are an important component of the forests of the Old World. However, few studies have been conducted on the distribution of these abundant palms within different habitats, specifically in Peninsular Malaysia. This study was aimed at assessing rattan diversity, abundance and biomass change across two different habitat types, namely, dipterocarp forests and fresh-water swamps within the Segari Melintang Forest Reserve, Perak, within two years. All rattan stems within five 100 m × 100 m sized study plots (A–E) of the two habitat types were counted in 2011 and 2013, and Shannon-Wiener diversity indices (H’) and Bray-Curtis dissimilarity indices were calculated. A total of 11 species from 5 genera (161 stems ha–1) were sampled. Rattan abundance was higher in all swamp plots; however, rattan diversity (H’) was highest in the dipterocarp plot (D: H’(2011)1.79; H’(2013)1.84). Bray-Curtis indices of rattan abundance (highest similarity in swamp: plot BC(2011) 0.484, BC(2013) 0.262) and biomass were highest for study plots with the same vegetation types in both years. For rattan biomass, the most similar plot pairs changed during the years: dipterocarp plots A and D were most similar in 2011 (0.509), and swamp plots B and C were most similar in 2013 (0.282). This study helped contribute information regarding the distribution and dynamics of rattans in a primary rainforest of Peninsular Malaysia.

 

Rotan (subfamily Calamoideae) adalah satu komponen penting dalam hutan paleotropik. Walau bagaimanapun, tidak banyak kajian yang dijalankan berkaitan kelimpahan palma ini, khususnya di Semenanjung Malaysia. Kajian ini bertujuan untuk menilai kepelbagaian rotan, kelimpahan, dan biomassa rotan di dua jenis habitat yang berbeza, iaitu hutan dipterokarpa dan paya air tawar di dalam Hutan Simpan Segari Melintang, Perak selama tempoh dua tahun. Semua batang rotan dalam lima plot kajian (A–E) berukuran 100 × 100 m setiap satu di kedua-dua jenis habitat telah dikira pada tahun 2011 dan 2013 dan indeks kepelbagaian Shannon-Wiener (H') dan indeks ketidak samaan Bray-Curtis turut dikira. Sebanyak 11 spesies dari 5 genera (161 batang ha–1) telah disampel. Kelimpahan rotan adalah lebih tinggi di plot kawasan berpaya, bagaimanapun, kepelbagaian rotan (H') adalah paling tinggi dalam kawasan dipterokarpa plot D: H'(2011)1.79; H'(2013)1.84. Indeks-indeks Bray-Curtis bagi kelimpahan (persamaan tertinggi di paya air tawar: plot-plot BC(2011) 0.484, BC(2013) 0.262) dan biomassa adalah tertinggi bagi plot kajian dengan jenis tumbuh-tumbuhan yang sama untuk kedua-dua tahun. Bagi biomassa rotan, pasangan plot paling serupa berubah dari tahun ke tahun: plot-plot dipterokarpa A dan D adalah paling serupa bagi tahun 2011 (0.509), plot-plot berpaya B dan C adalah paling serupa bagi tahun 2013 (0.282). Kajian ini dapat membantu dalam menyumbang maklumat kepada taburan spesies rotan tempatan di hutan hujan primer Semenanjung Malaysia.
Isolation and Characterisation of a Molybdenum-reducing and Metanil Yellow Dye-decolourising Bacillus sp. strain Neni-10 in Soils from West Sumatera, Indonesia
Authors: Rusnam Mansur  , Neni Gusmanizar  , Muhamad Akhmal Hakim Roslan  , Siti Aqlima Ahmad  , Mohd Yunus Shukor
Published: February 2017

A molybdenum reducing bacterium with the novel ability to decolorise the azo dye Metanil Yellow is reported. Optimal conditions for molybdenum reduction were pH 6.3 and at 34°C. Glucose was the best electron donor. Another requirement includes a narrow phosphate concentration between 2.5 and 7.5 mM. A time profile of Mo-blue production shows a lag period of approximately 12 hours, a maximum amount of Mo-blue produced at a molybdate concentration of 20 mM, and a peak production at 52 h of incubation. The heavy metals mercury, silver, copper and chromium inhibited reduction by 91.9, 82.7, 45.5 and 17.4%, respectively. A complete decolourisation of the dye Metanil Yellow at 100 and 150 mg/L occurred at day three and day six of incubations, respectively. Higher concentrations show partial degradation, with an approximately 20% decolourisation observed at 400 mg/L. The bacterium is partially identified based on biochemical analysis as Bacillus sp. strain Neni-10. The absorption spectrum of the Mo-blue suggested the compound is a reduced phosphomolybdate. The isolation of this bacterium, which shows heavy metal reduction and dye-decolorising ability, is sought after, particularly for bioremediation.

 

Satu bakteria penurun molibdenum dengan keupayaan baru untuk menyahwarna pewarna azo Kuning Metanil dilaporkan. Kondisi optimum untuk penurunan molibdenum adalah pada pH 6.3 dan pada suhu 34°C. Glukosa adalah penderma elektron yang terbaik. Keperluan-keperluan lain termasuklah kepekatan fosfat yang sempit di antara 2.5 dan 7.5 mM. Profil masa pengeluaran Mo-biru menunjukkan tempoh sela masa kira-kira 12 jam, jumlah maksimum Mo-biru dihasilkan pada kepekatan molibdat 20 mM dan pengeluaran maksimum pada masa 52 jam inkubasi. Logam-logam berat seperti merkuri, perak, tembaga dan kromium merencat penurunan sebanyak 91.9, 82.7, 45.5 dan 17.4%, masing-masing. Penyahwarnaan pewarna Kuning Metanil pada kepekatan 100 dan 150 mg/L berlaku pada hari ketiga dan hari enam inkubasi, masing-masing. Kepekatan yang lebih tinggi menghasilkan degradasi separa, dengan penyahwarnaan warna sebanyak 20% berlaku pada kepekatan 400 mg/L. Bakteria ini dikenal pasti secara separa berdasarkan analisis biokimia sebagai Bacillus sp. strain Neni-10. Spektrum penyerapan Mo-biru mencadangkan bahawa kompaun terhasil adalah fosfomolibdat terturun. Pengasingan bakteria ini, yang menunjukkan penurunan logam berat dan keupayaan penyahwarnaan pewarna, adalah diperlukan, terutamanya untuk bioremediasi.
Variation in Morphometric Characters in Four Sand Crab (Albunea symmysta) Populations Collected from Sumatra and Java Island, Indonesia
Authors: Febi Ayu Pramithasari  , Nurlisa Alias Butet  , Yusli Wardiatno
Published: February 2017

Variation in morphometric characters in four sand crab (Albunea symmysta) populations from four intertidal areas in Sumatra (Aceh and Bengkulu) and Java (Cilacap and Yogyakarta) were studied. Crabs collected from the four sites were measured to obtain 10 morphometric characters, i.e., carapace length (CL), carapace width (CW), ocular peduncle length and width (LOP and WOP), telson length and width (LT and WT), merus length (ML), carpus length (CaL), propodus length (PL), and dactylus length (DL). Allometric relationships were established among three morphometric characters (CW, PL, and DL) for each site, in which CL was fixed on the abscissa as a reference variable. The analysis of covariance showed that population from Yogyakarta had a greater carapace width and the Aceh population had a longer dactylus length. In terms of propodus length, the Aceh population had a longer dactylus length than the Bengkulu population. Two group populations were detected by cluster analysis with 10 morphometric characters, i.e., the Sumatra population and the Java population.
Technical Problems of Splenectomy in Hematological Diseases
Authors: Karagyulyan S.R. , Danishyan Karen Ismailovich , Shutov S.A. , Silaev M.A.
Published: February 2017

The article focuses on the technical aspects of splenectomy (SE) in 1628 patients using two main techniques: laparoscopy (885 SEs) and laparotomy (743 SEs), with a description of various factors that influence the invasiveness and the success of the surgery. The fact is that in addition to the shape and size of an enlarged spleen, the technical complexity of the SE, especially in laparoscopic access depends on the following factors: perisplenitis, close presentation and fusion of the tail of the pancreas to the spleen, tumor infiltration of splenic vascular pedicle, branchy type of its structure, visceral obesity, compression of the splenic pedicle with enlarged and united lymph nodes. In most cases (60 %), there is a combination of several risk factors, thus making the surgery even more difficult. The indications for splenectomy, as well as its influence on the course of the main hematological disease are not considered in this paper.
Recommendation for Sedation and General Anesthesia in Different Tests and Procedures in Pediatric Oncohematology
Authors: Matinyan Nune Vanunievna , Valiev T.T.
Published: February 2017

Current anti-tumor chemotherapy programs for pediatric oncohematological disorders treatment imply diagnostic and therapeutic procedures under sedation. Based on the international and our own experience, this paper lists recommendations for the optimal anesthesia method for different manipulations in oncohematology.
Stevens-Johnson Syndrome after Treatment of Female Patient with Small Lymphocytic B-Cell Lymphoma, Autoimmune Hemolytic Anemia and Antiphospholipid Antibody Syndrome with Rituximab
Authors: Melikyan A.L. , Subortseva Irina Nikolaevna , Kovrigina A.M. , Kolosheinova T.I. , Egorova E.K. , Pustovaya E.I.
Published: February 2017

Stevens-Johnson syndrome is a severe delayed type systemic allergic reaction which affects the skin and mucous membranes. In adults, Stevens-Johnson syndrome is usually caused by the administration of drugs or a malignant process. The paper presents a case of Stevens-Johnson syndrome after the treatment of a female patient with small lymphocytic B-cell lymphoma, autoimmune hemolytic anemia and antiphospholipid antibody syndrome with rituximab. A rare combination of Stevens-Johnson syndrome and small lymphocytic B-cell lymphoma of small lymphocytes, as well as the development of severe delayed type systemic allergic reaction to introduction of rituximab are of special interest. A detailed medical history and the clinical manifestations of the disease allowed to diagnose Stevens-Johnson syndrome at early stages and prescribe an adequate therapy. As a result of the treatment, the patient’s condition has improved considerably. Symptoms of general toxicity were arrested completely; there was a complete epithelization of erosive defects. Therefore, the presented clinical observation shows that timely diagnosis, complex drug therapy, and comprehensive care can cure the diseases as soon as possible and prevent complications.
Primary Mediastinal (Thymic) Large B-Cell Lymphoma
Authors: Tumyan Gayane Sergeevna , Zavodnova I.Z. , Kichigina M.Yu. , Medvedovskaya E.G.
Published: February 2017

Primary mediastinal (thymic) large B-cell lymphoma (PMB-CL) is one of the primary extranodal tumors and originates from thymic medulla B cells. The disease is more common in young women and declares itself by mainly locally advanced growth within the anterior upper mediastinum with frequent involvement of chest organs. PMBCL has specific morphological, immunological, and genetic characteristics that permit to differentiate it from other similar diseases: diffuse large В-cell lymphoma, nodular sclerosis Hodgkin’s lymphoma, and mediastinal gray zone lymphoma. Immunochemotherapy with subsequent irradiation of the residual mediastinal tumor is the standard treatment of PMBCL. No benefits of one drug therapy over another have been demonstrated to date in controlled studies. Application of new imaging techniques (PET/CT) may result in withdrawal of the radiotherapy in some PMBCL patients without impairment of delayed survival rates.
Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Authors: Ponomarev Aleksandr Vasil'evich
Published: February 2017

Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells. It includes phenotype variants, mechanisms of the suppressive effect on the immune system, and tumor recruitment mechanisms of myeloid suppressors. It provides a brief description of works which studied myeloid suppressor in oncohematological diseases including multiple myeloma, lymphomas, and leukemias.
Effectiveness of Search for an Unrelated Donor of Hematopoietic Stem Cells using Russian Date Base "Bone Marrow Donor Search": Experience of Raisa Gorbacheva Memorial Institute for Children Oncology, Hematology and Transplantation
Authors: Makarenko O.A. , Alyanskiy A.L. , Ivanova N.E. , Kucher Maksim Anatol'evich , Babenko E.V. , Estrina M.A. , Pevtcov D.E. , Golovacheva A.A. , Kuzmich E.V. , Afanasyev B.V.
Published: February 2017

Background & Aims. The key condition for allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the presence of HLA-compatible related or unrelated donor. If related donor is not found, further search is carried out in the Bone Marrow Donor Worldwide (BMDW) international data base, which is not effective enough (about 80-85 %), because of genotype specificity of Russian Federation residents. The recruitment procedure using BMDW takes a lot of time and is expensive. Therefore, there are good reasons to develop an alternative Russian data base, Bone Marrow Donor Search (BMDS), which includes data from Russian bone marrow donor registries and has a good potential. The aim is to evaluate the effectiveness of hematopoietic stem cell (HSC) donor search and transplant quality using the BMDS search system. Methods. 34 allo-HSCT recipients with malignancies and hematological diseases were enrolled in the study in RM Gorbacheva Scientific Research Institute of Pediatric Hematology and Transplantation from November, 2012, to March, 2016. A HLA-compatible donor was found for each patient in the BMDS (www.bmds.info), which includes data from 13 Russian registries of HSC donors. Results. 34 allo-HSCTs were performed from unrelated donors recruited using Russian registries: 1 in 2012; 3 in 2013; 5 in 2014; 21 in 2015; and 4 in the 1st quarter of 2016. The greatest effectiveness of the BMDS search was in 2015 (14 %, n = 17). In 30 cases (88.2 %) a complete 10/10 compatibility for 5 HLA-gene loci was observed; in 4 cases (11.8 %) there was an incomplete compatibility (9/10). AB0 compatibility was only in 7 cases (20.6 %). In 15 cases (44.1 %) bone marrow was used for transplant harvesting; in 19 cases (55.9 %) peripheral blood stem cells were harvested by means of cytapheresis. The CD34+ count in the transplant was 1.2-12.0 х 106 CD34+ cell/kg (median: 5.0 * 106 CD34+ cell/kg). Engraftment was observed in 79.4 % of cases (п = 27), graft failure in 17.7 % of cases (n = 6), and early posttransplant mortality in 2.9 % of cases (n = 1). Conclusion. There was an increasing efficiency of search for a HLA-compatible unrelated HSC donor using a Russian BMDS search system for Russian residents with a graft quality similar to the one found in the international BMDW database.
Acute Myeloblastic Leukemia and Myelodysplastic Syndrome: Azacitidine for Prophylactic and Preventive Purposes after Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Ovechkina V.N. , Bondarenko S.N. , Morozova E.V. , Moiseev I.S. , Slesarchuk O.A. , Smirnova A.G. , Uspenskaya O.S. , Gudozhnikova Ya.V , Osipova A.A. , Sergeev V.S. , Mamaev N.N. , Zubarovskaya L.S. , Afanasyev B.V.
Published: February 2017

Aim. To evaluate the effectiveness of preventive and prophylactic post-transplantation therapy using azacitidine (5-AZA) in patients at high risk of post-transplantation relapse. Methods. 136 patients were included in the study performed by the pairwise comparison: 68 of them received 5-AZA after allo-HSCT and 68 patients were included in the historical control group. 5-AZA was prescribed for prophylactic or preventive purposes. The results were assessed according to the OS, RR, EFS, DUM, and relapse-free and GVHR-free survival. Results. 1-year OS was 76 % in the 5-AZA group (95% CI 60-84 %) and 44 % in the reference group (95% CI 33-55 %) (р = 0.001); 2-year OS was 63 % (95% CI 39-67 %) and 37 % (95% CI 26-48 %) (р = 0.007), respectively. The relapse rate (RR) in the 5-AZA group was 34 % (95% CI 22-46 %) during 1 year and 51 % (95% CI 38-64 %) in the reference group (р = 0.02). 1- and 2-year disease unrelated mortality (DUM) was similar: 5 % in the 5-AZA group (95% CI 0.1-14.0 %) and 25 % (95% CI 13-37 %) in the reference group (р = 0.005). 1-year EFS was 76 % in the 5-AZA group (95% CI 61-85 %) and 44 % in the reference group (95% CI 33-55 %) (р = 0.001); 2-year EFS was 63 % (95% CI 39-67 %) and 37 % (95% CI 2648 %) (р = 0.01), respectively. 1-year relapse-free and GVHR-free survival was 55 % in the 5-AZA group (95% CI 41-69 %) and 28 % in the reference group (95% CI 17-39 %) (р = 0.001); 2-year relapse-free and GVHR-free survival was 47 % (95% CI 32-62 %) and 27 % (95% CI 17-37 %) (р = 0.002), respectively. Conclusion. The use of 5-AZA for prophylactic and preventive purposes after allo-HSCT does not increase the risk of GVHR and DUM, does not suppress the GVL effect and can be used in combination with the donor lymphocyte infusion (DLI). The therapy with 5-AZA is safe during the early period after allo-HSCT. The drug does not suppress the GVL effect and can be used in high risk patients to prevent early post-transplantation relapse. The use of 5-AZA in combination with DLI does not increase the incidence of severe GVHR.
Features of Imaging of Different Types of Hodgkin’s Lymphoma Using Combined Positron Emission and Computed Tomography
Authors: Subbotin A.S. , Afanas'eva N.G.
Published: February 2017

Background & Aims. At present, PET-CT has an important clinical significance in Hodgkin's lymphoma (HL) and is used both for initial tumor staging and restaging and for the evaluation of treatment efficacy. Published data indicate the possible lack of radiotracer accumulation in the tumor tissue in HL before primary treatment. A low metabolic activity of the tumor tissue prior to treatment makes it difficult to assess the treatment dynamics during the anti-tumor therapy. The aim of this work is to determine the incidence of the low metabolic activity of tumor tissue in HL. Methods. Findings of 131 18F-fluorodeoxyglucose (FDG) whole body PET-CT scans of patients with histologically verified HL (over the period from 2011 to 2015) were studied retrospectively. Patterns of FDG accumulation in different histological types of HL, as well as the levels of metabolic activity in patients with tumor-related toxicity symptoms (B-symptoms) were studied. Results. The low metabolic activity was detected in 4 % of patients with de novo HL. The highest levels of metabolic activity were detected in nodular sclerosis and the lowest ones in nodular lymphocyte-predominant HL. Higher levels of radiotracer metabolic activity were observed in patients with general symptoms. Conclusion. In general, a high metabolic activity of the neoplasm is typical for HL. Primary staging before the treatment should be performed for a more accurate evaluation of dynamics of HL treatment outcomes, because in a number of cases a baseline low FDG accumulation in the neoplasm may imitate the absence of a viable tumor tissue in the affected lymph nodes at assessment of treatment results.
POLITICAL CORRUPTION PREVENTION IN REGIONAL ELECTION AFTER THE DECISION OF THE CONSTITUTIONAL COURT NO. 33/PUU-XII/2014
Authors: Soeroso Fajar Laksono
Published: February 2017

Political dynasty in the regional election in Indonesia has been canceled by the Constitutional Court (MK). In fact, the political dynasty is considered as elements that undermine the promotion of democracy and anti-corruption culture in Indonesia. Moreover, in case of corruption, political dynasty has a very close relationship with corruption, or commonly known as political corruption. By law, a political dynasty can no longer be resisted. Therefore, what is needed is how to prevent or at least to minimize the political corruption committed by the incumbent. This paper is set in 3 sub-headings, namely (a) corruption in Regional Elections: (b). Political Corruption by Incumbent; and (c) Political Corruption Prevention. Based on the analysis performed, the incumbent has broad access in economic, social, and politics which can provide a personal benefit to him or win his group in the elections. Therefore, the prevention of political corruption can be focused on (1) the financial preparedness and the control of campaign funds; (2) the opening of a space for people to demand commitment, consistency of attitude, and integrity of the incumbent in the fight against political corruption; and (3) enforcement of the rules must be carried out firmly without compromise
Laboratory efficacy and field effectiveness of hollow fiber membrane microfilters used for household water treatment in Honduras
Authors: Murray Anna L. , Stewart Barbara , Hopper Catherine , Tobin Ellen , Rivera Jimmy , Mut-Tracy Henry , Stewart Patrick , Stewart Cordelia , Tobin Claire , Goeb Mario , Meub Carolyn , Lantagne Daniele S.
Published: February 2017

The Sawyer PointONE™ hollow fiber membrane filter is increasingly promoted for long-term household water treatment in developing countries. Limited data demonstrate PointONE™ microbiological laboratory efficacy and short-term diarrheal disease reduction among users, but household microbiological data is lacking. To compare laboratory and household PointONE™ filter microbiological performance, we enumerated Escherichia coli (E. coli) and total coliforms in source and filtrate water from: (1) one new filter with E. coli-spiked water (107–109 CFU/100 mL) in the laboratory, (2) one new filter with natural Maine and Honduran surface waters, and (3) 50 filters used in Honduran homes for 1–3 years. In laboratory tests, all filtrate samples had <1 CFU/100 mL E. coli (>99.99999% reduction). In natural surface waters, all filtrate samples had ≤1 MPN/100 mL E. coli (≥99.5% reduction). In households, filtrate samples had geometric mean 5.1 MPN/100 mL E. coli (90% reduction), with only 30% of filtrate samples complying with international standards of undetectable E. coli. Total coliform presence in natural water filtrate varied for both new and household filters. The discrepancy between laboratory and household results and premature filter failure are not well understood. Further research is recommended to understand this performance disparity and determine filter failure mechanisms in households.
Impacts of onsite greywater reuse on wastewater systems
Authors: Penn Roni , Schütze Manfred , Alex Jens , Friedler Eran
Published: February 2017

Together with significant water savings that onsite greywater reuse (GWR) may provide, it may also affect the performance of urban sewer systems and wastewater treatment plants (WWTPs). In order to examine these effects, an integrated stochastic simulation system for GWR in urban areas was developed. The model includes stochastic generators of domestic wastewater streams and gross solids (GSs), a sewer network model which includes hydrodynamic simulation and a GS transport module, and a dynamic process model of the WWTP. The developed model was applied to a case study site in Israel. For the validation of the sewer simulator, field experiments in a real sewer segment were conducted. The paper presents the integration and implementation of these modules and depicts the results of the effects of various GWR scenarios on GS movement in sewers and on the performance of the WWTP.
Virtual simulators for distance training of seafarers
Authors: Fomina Inga Konstantinovna , Taranukha Svetlana Nikolaevna
Published: February 2017

The basic directions of development of the University information educational environment during the training of seafarers on the basis of the development of a distributed infrastructure of technical and software systems, implementation of virtual simulators to modelling conditions of quasiprofessional activity of seafarers have been formulated. The necessity of development of e-learning technologies for practical training on real physical hardware has been justified.
Learning computer technology in the development of educational practice «Care for surgical patients»
Authors: Dyabkin Evgeniy Vladimirovich
Published: February 2017

This article deals with the problem of implementation in the educational process of new computer technologies. Modern students of medical educational institutions need computer programs, which encourage them to absorb necessary educational material and stimulate cognitive interest in the subject. This training flash program is recommended for implementation in the educational process in educational practice and it consists of «Care for surgical patients» module. The computer program includes educational material, revealing the structure and equipment of the surgical department with the use of animation clip. In order to check the quality of learning, the student must pass a test and solve situational problems. This article is devoted to the indicated problem.
The analysis of improvement and maintenance of fire safety of forestry
Authors: Nguen Tuan An
Published: February 2017

The article has studied the main points of fire safety of forest in Russia. The order of actions of the relevant services and the people behavior during the fire season. Examining this issue, the author revealed shortcomings and vulnerabilities of large fire prevention system and imperfection of the legislative side of the issue and stated their reasons.
Quality evaluation of raspberry fruits, suitable for freezing, naturalized in the conditions of forest-steppe of Volga Region
Authors: Ruzavina Yulia Viktorovna
Published: February 2017

The article discusses the researches on raspberry freezing of naturalized sorts of breeding of Kokinsk stronghold of All-Russia Selection-Technological Institute of Horticulture and Nursery. Based on the tests of raspberry freezing, the authors could select more suitable kinds of this variety with quality determination of frozen fruits.
Optical checking of geometrical dimensions of current-carrying anode pins on soderberg electrolysers
Authors: Kadrov Denis Nikolaevich
Published: February 2017

This work addresses to the problem of wear-out of current-carrying anode pins of Soderberg electrolysers with an upper current supply. A task of automated checking of geometry of the current-carrying anode pin is analyzed. A possible method of checking of geometrical pin parameters is determined and described.
The review of CAD for simulation of microwave devices
Authors: Sirkeli Anna Ivanovna , Drach Vladimir Evgenievich
Published: February 2017

The article is devoted to a brief review of modern CAD for electromagnetic modeling of microwave devices. Five major CAD systems are described in the article: FEKO, μWave Wizard, Sonnet, AWR Microwave Office, HFSS. The main methods are given for each CAD system used for simulation of microwave structures and the main advantages that distinguish its use.
Designer drugs: a brief history of the attempt to systematize on the example of «spice» and «salts» (review)
Authors: Mrykhin Vladimir Valerievich , Antsyborov Andrey Viktorovich
Published: February 2017

The article reviews Russian and international literature on synthetic (designer) drugs. A special place is given to the most common designer drugs-synthetic cathinones («salts») and synthetic cannabinoids («spice»). On the basis of this literature the authors analyse the chemical structure of synthetic cathinones and synthetic cannabinoids, the psychoactive effects of these substances on the body, the ability to produce mental, somatic and neurological disorders.
The regulation of expression of the hormone leptin
Authors: Baranov Sergey Nikolaevich
Published: February 2017

This article discusses some ways of the process expression and its regulation of peptide hormone leptin, which performs the function of the endocrine mediator with the multi-action.
The role of trade union organization in solving labor disputes and strikes in Vietnam
Authors: Nguyen Thu Ha , Dang Xuan Giap
Published: February 2017

The article describes the role of the trade union organization in solving labor disputes and strikes and the legal basis of the role of trade union organization in solving labor disputes and strikes in Vietnam.
The research of the leading role of factors of intellectual and innovative development of the state
Authors: Markin Sergey Vladimirovich
Published: February 2017

There is a set of the factors influencing intellectual and innovative development of the state. There is a need to determine the fundamental factors influencing intellectual and innovative development of the state. For this purpose, according to the author it is necessary to consider various theories of state development and spheres of human life, in which innovative and intellectual development is observed.
Experience of panel-and-pillar development system application at the Zhaman-Aibat field (Republic of Kazakhstan)
Authors: Zharaspaev Madiyar Aspandiyarovich
Published: February 2017

The article summarizes the experience of previously adopted and applied parameters of the settings panel-and-pillar development system at the Zhaman-Aibat field. It shows the results of the analysis of geomechanical monitoring of structural elements of panel-and-pillar development system at the field during 2008–2010. The dependence of rock spalling from the roof has been withdrawn. The graphs on the fact of destruction of the pillars have been shown. The author concluded that there is a need to continue the research works in this direction.
The Experience of implementation of education technologies at the International University of Kyrgyzstan
Authors: Narkoziev Amanbek Karashovich
Published: February 2017

The article has covered the analysis of modern state of higher education system and the global processes occurring in it, which have a direct impact on the educational policy of Kyrgyzstan. The main concern is dedicated to the research of innovative forms of organizing the educational processes and the possibilities of their implementation into the higher education system of Kyrgyzstan.
The socialization of students in the process of art activity in a mixed-age organization
Authors: Khomenko Natalia Yurievna
Published: February 2017

The article analyzes the experience of pedagogical research of students’ socialization in the process of their art activity in a mixed-age organization. It also provides the characteristic of some results, obtained in the research.
Evaluating the effectiveness of single-well heat exchanger energy recovery system for its long-term operation
Authors: Bekker Vladimir Viktorovich , Grigoriev Sergey Vladimirovich
Published: February 2017

The paper deals with the effectiveness of the single well heat exchanger for extraction of deep heat energy of the bowels of the Earth. The classification of renewable sources of energy is presented. The authors describe the subsurface temperature regime on the territory of Russia and give definition to the concept of temperature reduction because of the use of the single well heat exchanger. The results of computational and parametric study of the single well heat exchanger are presented.
Comparison of current CASE-tools
Authors: Sunetov Timur Ruslanovich , Shestakov Dmitry Alekseevich
Published: February 2017

Modern CASE-tools cover a wide area of multiple systems support of design technologies – from simple analysis tools and documentation to the full automation equipment, covering the entire life cycle. All pieces of work on the topic mainly describe how to evaluate and the choice of thematic instruments, but they do not evaluate the CASE-tools, which are currently available on the market. This study aims to give an initial idea of the current CASE-tools on the market to have a better understanding of which product to choose, depending on the needs of the organization.
Linguistic means of explication of the US Army subculture ethnic stereotypes
Authors: Romanov Aleksandr Sergeevich , Romanova Valeria Vladimirovna , Osipova Inna Alekseevna
Published: February 2017

The current study’s area of research is characterized by the relations between “ethnos”, “culture” and “language” phenomena. The subject of the research consists of the linguistic means of explication of ethnic stereotypes of the US Army subculture.
Innovative technologies in primary school
Authors: Lyzentsova Lyudmila Aleksandrovna , Krasnova Gulnara Ravilevna
Published: February 2017

This article describes innovative technologies during the classes in elementary school. The author has noted that the introduction of new technology promotes the development of education and the student's desire to learn and fosters independence, initiative and tolerance.
The national spirit reflection in the memory of language and culture
Authors: Romanov Aleksandr Sergeevich , Romanova Valeria Vladimirovna , Osipova Inna Alekseevna
Published: February 2017

This research focuses on a dialectic interrelation between language and culture perceived as existential manifestations of the national spirit. Identity of the national linguistic world perception is defined by its social-historic development, geographic and climatic conditions of living and distinctiveness of the national linguo-cultural heritage.
New technologies as a factor of development of competitive Russian economy in the context of a post-industrial stage
Authors: Shamrai Yuriy Fedorovich
Published: February 2017

The article presents ways of development of a technological platform of the Russian economy and a role of new technologies and «human factor» in providing its competitiveness at a post-industrial stage. The author offers: education systems development, use of channels of the international migration of a skilled labor force, forming of the national market of new technologies, enhancement of interaction with the world market of new technologies.
A ESTABILIZAÇÃO DA TUTELA ANTECIPADA COMO INSTRUMENTO DE EFETIVIDADE DA JURISDIÇÃO EM FACE DO DIREITO FUNDAMENTAL AO CONTRADITÓRIO
Authors: Pinheiro Natalia , Diniz Campos Juliana Cristine
Published: February 2017

O presente artigo tem como objeto de estudo o instituto processual de estabilização da tutela antecipada de urgência e como perspectiva de análise a teoria dos direitos fundamentais. Pretende-se investigar a fundamentalidade material do instituto tomando como premissa teórica a dupla natureza do princípio do acesso à justiça enquanto direito e garantia fundamental. Nessa linha de pesquisa, defende-se a tutela antecipada de urgência e sua estabilização como regra instrumental do direito fundamental de acesso à justiça e como conteúdo assecuratório derivado da garantia fundamental de acesso à justiça. Defende-se, contudo, que a fundamentalidade material do instituto somente poderá ser sustentada se a estabilidade de uma tutela proferida no âmbito da cognição sumária não ofender, em sua gênese, o direito fundamental ao contraditório.