bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Trauma Belief and Secondary Traumatic Stress: The Mediating Effect of Intrusive Rumination
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Cho Su-zi , Ha Jung-hee
Published: January 2023

Objectives The purpose of this study was to examine the relationship between traumatic beliefs, invasive rumination, and secondary traumatic stress in adults who experienced indirect trauma, and to verify the mediating effect of invasive rumination in the relationship between traumatic beliefs and secondary traumatic stress.
Methods In order to verify the research hypothesis, a questionnaire survey was conducted on a total of 354 people. Among them, 33 copies were excluded and analyzed based on 321 copies. The scales used were the Trauma and Attachment Belief Scale (TABS), the Korean Event Related Rumination Inventory (ERRI), and the Invasive Rumin Scale, the Secondary Traumatic Stress Scale (KSTSS). Based on the collected data, it was analyzed through SPSS 21.O and PROCESS macro 3.4 program. The results of this study are as follows.
Results First, as a result of examining the demographic variables of this study, most people (20.2%) experienced ‘accidents and injuries (traffic accidents, industrial accidents, fires, explosions, etc.)’ as indirect trauma, and ‘Most people answered (35.2%) because they felt sorry for their family or neighbors. In addition to trauma survivors, this is significant in that it helps in the treatment and counseling strategies of family and acquaintances exposed indirectly. Second, this study was targeted at general adults considering that indirect trauma studies targeting general adults were insufficient, including domestic studies, because prior work on the subject of indirect trauma was mainly targeted at practitioners related to trauma. Is meaningful in that respect. Third, it is significant in that the study results provide information about the main symptoms and the effects of secondary trauma stress in a counseling scene with a client who has experienced indirect trauma and suggests that it is a cognitive direction.
Conclusions Based on the above results, we can examine the characteristics of adults who experienced indirect trauma and the main variables affecting secondary trauma stress, and posttraumatic stress disorder (PTSD), which can occur in trauma survivors, indirectly injuries trauma. It was found that even those who experienced it could occur with secondary traumatic stress. Finally, limitations were discussed for further study.
An Exploration on Teaching Strategies of Case-Based Learning from the Dewey's an Experience
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Chae Juhye , You YeongMahn
Published: January 2023

Objectives In this study, in order to overcome the difficulties learners experience in the case-based learning process, an effective teaching strategy was explored based on Dewey's concept and philosophy of ‘an experience’.
Methods First, the difficulties learners experience in a CBL curriculum were traced through in-depth interviews and participation observations. Second, in light of Dewey's concept of ‘an experience’, the learning experiences required for effective CBL were identified according to six types. Finally, based on one type of experiential teaching strategy and the main points of each type of teaching strategy, the teaching strategy of case-based learning was explored.
Results An experience teaching strategy for effective case-based learning was presented in six types according to the characteristics of ‘an experience’. To reduce the difficulties experienced by learners of CBL and to enable effective CBL by linking acquired knowledge and theory to practice, teaching strategies for CBL and specific guidelines based on Dewey's ‘an experience’ were drawn.
Conclusions Based on a comprehensive understanding and practical approach that integrates theory and practice for CBL, this study provides implications for how a teacher utilizing CBL can facilitate effective learning in light of ‘an experience’.
The Moderated Effect of Self-Control in the Relationships among Mindset, Grit, and Task Engagement in University Dance Classes
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Dae Won
Published: January 2023

Objectives According to Carol Dweck(2006), our mindset is the collection of thoughts and beliefs that shape our thoughts or habits. The purpose of this study was to investigate the grit and self-control in the relationship between mindset and task engagement among college dance students.
Methods A questionnaire comprised of the mindset scale, grit scale, self-control scale, and task engagement scale was administrated to 485 male and female students (mean age 20.52). Correlation analyses, simple mediation analyses, and moderated mediation analyses for testing the hypothesis using PROCESS macro were performed.
Results We found that grit positively mediated the relationship between growth mindset and task engagement, whereas that grit negatively mediated the relationship between fixed mindset and task engagement. The influence of grit on the relationship between mindsets and task engagement was moderated by self-control.
Conclusions The results indicated that grit and self-control were key factors for facilitating college dancers’ task engagement.
On the Exploration and Problem Solving Related to Tangent Lines of Quadratic Curves via Dynamic Geometry
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Hyun Jeong , Cho Minshik
Published: January 2023

Objectives The purpose of this study is to explore methods of effective teaching the tangent line of quadratic curves in a dynamic geometric environment.
Methods The exploratory software GeoGebra was used as a dynamic geometric environment, and the activity worksheets for exploring the geometric properties of the tangent line to quadratic curves were developed. The changes in students’ perspective of geometry appeared were examined and their influences were analyzed.
Results The results show that the dynamic geometric environment is significant as a means for students to think geometrically by intuitive observation and explore the inherent properties of the tangent line to quadratic curves. Teaching from the perspective of geometry made students change their views that they need to memorize formulas and be familiar with the types of problems to learn quadratic curves. There is a positive response about changes in students understanding the problem situations and leading the solving process.
Conclusions The result of this study provides some useful implications to geometry education that harmonize perspectives of analytic geometry and synthetic geometry.
A Study on the Recognitive Characteristics of High School Students with Excellent Reading Ability
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Eunhye , Park Youngmin
Published: January 2023

Objectives The purpose of this study is to analyze the cognitive, deterministic, and environmental characteristics of high school students with excellent reading comprehension skills, and to obtain information on improving reading comprehension.
Methods To that end, out of 16 high school students in Gangwon Province, 16 who had proven excellent reading comprehension were interviewed individually. The interview consisted of answers to a total of 28 questions classified into cognitive, deterministic, and environmental factors related to reading.
Results First, high school students with good reading skills were adept at using reading strategies and demonstrated superior achievement based on extensive vocabulary and background knowledge, but perceived reading categories somewhat restrictedly. Second, it was found that high school students with excellent reading ability had positively formed reading attitude, reading motivation, and reading efficacy, which are factors of reading justice, and that these showed a static correlation with reading ability. Third, it was found that the rich home literacy environment of high school students with excellent reading ability had a positive effect on the development of reading ability.
Conclusions Reading comprehension is comprehensively developed under the influence of cognitive, deterministic and environmental factors. In order to develop students with excellent reading comprehension, there should be a comprehensive approach to the development of defining elements and the improvement of the literacy environment, without being biased toward cognition.
Exploring the Component of the Fear of Failure Perceived by Team Sports Players
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Kyung-Ha , Choi Jae-Won
Published: January 2023

Objectives In this study, we will investigate the fear of failure of team sports players, analyze in-depth what structure it is composed of, and explore the components that hinder players' performance.
Methods To this end, this study adopted an open questionnaire and an in-depth interview method. The open questionnaire was surveyed on 260 middle, high school, and university team sports players, and the data collected through this were inductive content analysis. After that, in-depth interviews were conducted one-on-one interviews with nine team sports athletes with experience of failure to grasp in-depth the fear of failure of team sports players.
Results The results of this study were categorized by deriving 5 general areas and 9 detailed areas through inductive content analysis of 582 raw materials collected through open questionnaires, and general areas were categorized as ‘Repeated mistakes’, ‘Injuries and Rehabilitation’, ‘Out of Competition’, ‘Self-Blame’, and ‘significant other's evaluation’. The detailed factors of the “Repeated mistakes” are repeated mistakes, and the detailed factors of the “Injuries and Rehabilitation” factor were incompetence and injury rehabilitation. The detailed factors of the “out of competition” factor were position threats and enter school/career threats, the detailed factors of the “self-blame” factor were guilt and shame, and the detailed factors of “significant other's evaluation” were leaders and parents.
Conclusions Fear of failure is a psychological factor that adversely affects the player, instills negative emotions, and lowers performance. The results of this study revealed why players feel afraid. In order to find a solution to this and provide detailed psychological support to athletes, it is believed that members in the sports environment should take the lead together. This could ultimately lead to results that help the players improve their performance.
A Study on the Motivational Aspects of Korean Reading of Foreign Undergraduate Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Eunjin
Published: January 2023

Objectives The purpose of this study is to reveal the educational implications related to the reading motivation of foreign students by exploring the subfactors of Korean-reading motivation by targeting foreign undergraduate students in Korea and examining the difference in Korean-reading motivation according to the learners’ variables related to gender, nationality, and level.
Methods To this end, the test was conducted using the foreign language reading motivation scale of Lee & Kwon (2022), which was developed based on the reading motivation theory of Watkins & Coffey(2004), Mori(2002), etc. on 86 foreign undergraduate students attending 4 universities in Seoul and Busan, from the May to June 2022, and the results were statistically verified by SPSS 26.0.
Results As a result of the study, the motivation for domestic foreign undergraduate students to read Korean was extracted into 6 subfactors: (1)reading challenge motivation, (2)reading importance motivation, (3)efficacy motivation, (4)fiction motivation, (5)non-fiction motivation, and (6)recognition and competition motivation. In addition, as a result of confirming the difference of patterns in reading motivation according to the learners’ variables, The difference in motivation according to gender found that men are more motivated than women in reading efficacy motivation and women are more motivated than men in reading challenge motivation and fiction motivation. The motivation factor according to nationality showed statistically significant difference only in reading challenge motivation, and the difference in motivation according to the TOPIK level showed that 3rd and 4th grade acquirers had a higher motivation than 5th and 6th grade acquirers in recognition and competition motivation.
Conclusions In the field of Korean reading education as a foreign language, given that discussions such as reading motivation in affective aspects and the results of the study have been relatively insignificant, the results of this study are meaningful as a study that investigated the Korean reading motivation of foreign students, identified subfactors, and statistically identified differences in motivation patterns according to learners' variables. The results of this study are basic and empirical study on the reading motivation of foreign students, which can be used as basic data for teaching and learning of foreign undergraduate students in Korea.
Assessment of antibacterial activity of some extracts of Securinega virosa (Roxb. ex Willd.) Baill on pathogens bacteria
Authors: KOUANGBE Mani Adrien , TCHUMOU Messou , KONE Monon , OUATTARA Karamoko , N’GUESSAN Jean David
Published: January 2023

Today, faced with the emergence of microbial resistance to antibiotics, the renewal of the arsenal of anti-infective drugs is acutely posed. In order to explore other sources of anti-infective drugs, this study therefore proposed to evaluate the antibacterial activity in vitro of several extracts of Securinega virosa, a well-known combretacea of populations in northern Côte d'Ivoire. To achieve this objective, the method of determining the diameters of the zones of inhibition on wells in an agar medium as well as that of the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration were carried out. The results showed that the aqueous extract was not active on all the bacteria tested. The dichloromethane fraction at 500 mg/mL inhibited growth of Shigella Typhi (12.5 mm), followed by Streptococcus sp. (12.33 0.25 mm) and Staphylococcus aureus Meti-R (11.75 1.25 mm). The ethyl acetate fraction inhibited primarily Gram-positive bacteria with average diameters of 12 mm to 500 mg/mL. The ethanol fraction was most active on all bacteria with inhibition diameters ranging from 9 to 13.33 mm to 500 mg/mL. It showed the lowest MIC (3.12 mg/mL) on gram-positive and large Gram-negative levels ranging from 12.5 to 50 mg/mL. This study through its results provides data in favor of the traditional use of Securinega virosa in therapy.

Keywords : Securinega virosa, in vitro, antibacterial, activity
Evaluation of acute, subacute toxicity and in vivo impact of aqueous decoction of Flemingia faginea Guill. & Perr. (Barker) leafy stems on NMRI mice and normotensive Wistar rats
Authors: OUEDRAOGO Windingoudi Rimwagna Christian , BELEMNABA Lazare , NITIEMA Mathieu , KABORE Boukaré , COMPAORE Souleymane , KOALA Moumouni , SEMDE Rasmané , OUEDRAOGO Sylvin
Published: January 2023

Introduction: Flemingia faginea, a Fabaceae family medicinal plant, has been used for a long time in Burkina Faso for the treatment of hypertension and excess salt. However, the safety of the preparations derived from this plant has not yet been scientifically documented. This study aimed to evaluate the acute and subacute oral toxicity of the leafy stems aqueous decoction of F. faginea (FAD) in healthy normotensive mice and rats and the impact on their normal blood pressure. Material and Methods: The acute oral toxicity study was conducted according to the toxicity class method of the Economic Cooperation and Development Organization (OECD) guideline 423. Subacute toxicity was carried out according to the OECD Guideline 407 for repeated dose chemical toxicity for 28 days. Hematological and biochemical analyzes of blood were performed after autopsy. An evaluation of the impact of the extract on the blood pressure of rats was performed using the non-invasive method. Results: A single oral dose of 2000 mg/kg bw to mice did not cause mortality or clinical signs or symptoms of toxicity during the 14-day study. The FAD was classified in the fifth category of the Harmonized System of Classification of the United Nations and considered practically safe with an estimated 50% lethal dose of 5000 mg/kg bw. Daily gavage of male and female rats with doses of 100,500 and 1000 mg/kg did not result in mortality or significant adverse effects during the 28days of experimentation. There were no significant differences in body weight gain, food &water consumption or relative vital organ weights in treated animals. Analysis of the hematological and biochemical parameters of blood serum did not show significant differences between treated and control animals in this study. Additionally, no aberrant changes were found in the systolic and diastolic blood pressures of the test animals during the 28 days of inclusion compared to those of the control group. Conclusion: The extract FAD could be considered safe within the doses tested for the results of the toxicological evaluation. However, microscopic, histopathological, and subchronic investigations will have to be carried out to confirm the safety of this extract use.
Direct nose-to-brain delivery of diazepam via trigeminal nerve contributes to rapid seizure suppression in pentylenetetrazole-induced status epilepticus model rats
Authors: Watanabe Kazutoshi , Kimura Soichiro , Hazama Yutaro , Morimoto Yasunori , Ueda Hideo
Published: January 2023

The purpose of our present study was to elucidate the involvement of the direct transfer to the brain after intranasal (i.n.) administration of diazepam (DZP), and to provide findings whether i.n. the administration could be used to obtain rapid onset of pharmacological action. We determined the blood and brain kinetics of DZP after administrations of i.n. and other routes, and the relationship between their concentrations and rapid seizure suppression effect; furthermore, and evaluated the distribution process of DZP to the brain. There was a negative connection between the plasma concentration and the amount of DZP delivery to the brain from the systemic circulation during the period that followed intravenous and intrarectal injection before the onset of seizure suppression. I.n. administration resulted in the seizure suppression time below the correlation curve: the seizure suppression effects were observed earlier than estimated despite the low plasma concentrations of DZP, suggesting the involvement of direct nose-to-brain delivery of DZP. The time to maximum concentration (Tmax) in the forebrain, hindbrain, olfactory bulb (OB), trigeminal nerve (TN), and cerebrospinal fluid (CSF) after i.n. the administration was 3 min, which was shorter than the Tmax of the plasma concentration. In fluorescence imaging using Rhodamin-B-base, the TN and the area of the vicinity of the thalamus had stronger fluorescence 1 and 3 min after i.n. administration, compared with the OB and CSF. In summary, direct brain delivery of DZP requires the TN and it was suggested that distribution to the vicinity of the thalamus via the TN may be connected to the quick seizure suppression effect.

Keywords: Status Epilepticus, Diazepam, Intranasal Administration, Nose-to-Brain, Trigeminal Nerve
The Potentials of Herbal Plant against the Psoriasis
Authors: Sanap Jayshree B , Chandewar Anil V. , Kochar Nitin , Nagrik Shatrughna Uttam
Published: January 2023

Chronic autoimmune skin disease termed psoriasis is characterised by excessive keratinocyte multiplication, scaly plaques, severe inflammation, and erythema. T lymphocytes, leukocytes, vascular endothelium, and epidermal keratinocytes also contribute in the pathogenesis of psoriasis. Increased leukocyte recruitment and increased levels of cytokines, growth factors, and genetic factors like interleukin (IL)-1, IL-6, IL-17, IL-22, IL-23, tumour necrosis factor (TNF), interferon (IFN), transforming growth factor (TGF), toll-like receptor (TLR)-2, signal transducer and activator of transcription (STAT-3), 15-lipoxygenase (LOX)-2. The most important aspects impacting the treatment of psoriasis are coiled-coil alpha-helical rod protein 1 (CCHCR1), steroidogenic acute regulatory protein (StAR), and vitamin D receptor (VDR). Various synthetic medicinal drugs have also been known to have the side effect of psoriasis. Due to their safety and accessibility, herbal medications may indicate the potential as effective anti-psoriatic agents.

Keywords: Psoriasis, Herbal Drug, Silybum marianum, Thespesia populnea, Mahonia aquifolium
EXPERIENCE IN THE IMPLEMENTATION OF AN AUTOMATIC WELDING PLANT IN THE PRODUCTION OF SMALL AGRICULTURAL MACHINERY
Authors:   Federal Scientific Agroengineering Center VIM, CHAVDAROV ANATOLIY
Published: January 2023

The most important trend in the development of modern technical production is increasing labor productivity and the quality of products. One of the main technological processes is the process of semi-automatic welding of various MIG units. The use of modern welding inverter semi-automatic machines allows you to obtain high-quality seams with the appropriate qualification of the welder. In a global scale, there are the acute shortage of qualified welders and the dependence of the resulting welded joints on the human factor. (Research purpose) The research purpose is analyzing the existing technology of welding transmission shafts in the production of small agricultural machinery at a particular enterprise and propose the introduction of an automatic welding machine for this operation. (Materials and methods) The article describes the complexity of performing the operation of assembling and welding two transmission shaft flanges for each standard size according to the existing technology and presents the timing results for each operation. (Results and discussion) An automatic installation with pneumatic holding and positioning of two flanges and a pipe was proposed to shorten the production cycle and eliminate the human factor. The article presents a block diagram of the installation with a programmable logic controller and a touch operator panel. The article also presents the design documentation, a prototype and results of production tests of the installation at the enterprise. Authors have developed a technological scheme for welding two ring seams. (Conclusions) The assembly process of the node by the worker was completely excluded from the technological map. The time of the full cycle for assembly and welding of the unit has been reduced by three times. The human factor was eliminated from the welding process and doesn’t influence the quality of the operation. The introduction of an automatic installation made it possible to use low-skilled personnel in this operation.
MULTIFUNCTIONAL DIGITAL TOOLS FOR TRACTOR DIAGNOSING
Authors: KOSTOMAKHIN MIKHAIL , SAYAPIN ALEKSANDR , PESTRYAKOV EFIM , PETRISHCHEV NIKOLAY
Published: January 2023

Agricultural producers and agricultural machinery enterprises are trying to minimize the risks associated with external and internal stress factors caused by changes in logistics and financial spheres. Risks can be minimized with the service maintenance of equipment, which is based on the use of FMEA analysis and CALS technologies. There is a need to develop multifunctional digital diagnostic tools. (Research purpose) The research purpose is analyzing the systems used to monitor the technical state of equipment and determining the possibilities of developing and manufacturing experimental multifunctional digital tools for the resource diagnostics of tractors. (Materials and methods) Data from domestic and foreign manufacturers of diagnostic equipment, as well as standards regulating the technical operation of agricultural tractors and machines by monitoring the technical condition were used. With the current level of availability of digital diagnostic tools during daily maintenance, it is difficult to determine deviations in technical condition at the initial stages in re-sourcedetermining nodes and components. (Results and discussion) In order to minimize technological risk, Gostechnadzor use digital means of instrumental control during inspection, and continuous information support technologies are implemented by the technological portal of the Ministry of Agriculture of Russia - the Federal State Information System for Accounting and Registration of Equipment. According to GOST R 27.013-2019, experimental samples of multifunctional digital diagnostic tools, assessment of expenditure of resource indicators, which can serve as prototypes for the creation of digital monitoring systems, are developed and presented. (Conclusions) The conducted analysis and research have shown the possibility of further improvement of tractor maintenance through the development and implementation of new multifunctional digital diagnostic tools.
EXPERIENCE IN THE ELECTROSPARK LAYERING TECHNOLOGIES FOR MACHINE PARTS
Authors:   Federal Scientific Agroengineering Center VIM, KOSTYUKOV ALEKSANDR
Published: January 2023

When the cost of new spare parts has sharply increased, the problems of restoring worn parts are relevant. (Research purpose) The research purpose is to present the most promising technological processes for the restoration of parts of internal combustion engines by the electric spark processing. (Materials and methods) The article presents a description of new generation installations for electric spark processing BIG-5 and their technical characteristics. Tool alloys 65G, SHX15, P6M5, as well as hard alloys and bronzes were used as alloying materials. Conductive materials with high electrical and thermal conductivity, erosion resistance were used to perform the operation of melting the deposited alloying layer. These primarily include copper, tungsten and graphite. (Results and discussion) The article presents developed technological processes and provides a list of details where electric spark processing is successfully used and a detailed description of the technological process of restoring several basic parts, recommends application modes and materials. The main principle of restoring operability is to increase the hardness and bearing capacity of the working surface, as well as the selection of optimal friction pairs. The production tests of technologies confirm 100 percent of the life of the restored parts. The cost of restoration using electric spark processing does not exceed 30-40 percent of the cost of the part. (Conclusions) The examples of restored parts show the effectiveness of the electric spark processing technology, as well as the reduction of labor intensity and cost of work related to the repair and restoration of machines. Electric spark coating is in many ways superior to known technologies in terms of the quality of the resulting surface and labor costs, it is characterized by low energy consumption, simplicity, high utilization of electrode material and environmental friendliness of the process.
United States Facility Management Industry Demographic Trends and Contemporary Workforce Challenges
Authors: Call Steven
Published: January 2023

Purpose -

The purpose of this research is to better understand the current state of the United States' FM profession by evaluating workforce demographic trends in identifying contemporary recruitment and hiring challenges facing the FM industry.

Methodology -

A survey was developed based upon available literature including past research and industry surveys. Demographic information was sought to understand respondents gender, race, ethnicity, age, retirement timeframes, and educational attainment. Input from a panel of FM subject matter experts was also secured prior to completion of the survey. The survey was sent electronically in February 2021 to more than 12,400 members of IFMA; a total of 3,557 survey responses were received by April 2021 for a 29 percent response rate. Only information from the 2,069 US respondents was used in this research.

Findings -

The US FM industry is getting younger, in part due to the growing number of FM college graduates. Nevertheless, a majority of facility managers will be retiring within the next decade and adoption of FM succession planning is sluggish. While recruitment of entry-level FM talent has become easier, recruiting senior level FM talent is a major challenge. Furthermore, there has been relatively no growth in the portion of females and minorities making up the FM workforce population over the past decade. Understanding challenges related to recruitment and succession of senior level FM profession, and a more inclusive workforce, is imperative for the FM industry to better attract and sustain a competent and diverse workforce.

Originality/value -

The results of this research are valuable in understanding current recruitment, retention, and hiring challenges within FM to help the industry address historical workforce attrition concerns.
Lnc-TIM3 propels childhood acute lymphoblastic leukemia progression by sponging miR-5094
Authors: Sun Jing , Zhao Jiou , Fu Wenfeng , Li Huimin , Chen Chuqin , Kang Meiyun , Fang Yongjun , Wang Yaping
Published: January 2023

Background Childhood acute lymphoblastic leukemia (cALL)
involves the aberrant expression of lncRNAs. This study aimed to clarify
the mechanisms of Lnc-TIM3 in cALL. Procedure The
expression of Lnc-TIM3 in cALL bone marrow, cell lines were
analyzed by quantitative real-time PCR (qRT-PCR). Cell migration,
invasion were evaluated by transwell. CCK8 assays, soft agar colony
formation, flowcytometry was used to measure the proliferation ability.
The xenografts of zebrafish were analyzed to explore the roles of
Lnc-TIM3 in vivo. The ceRNA regulatory mechanism of
Lnc-TIM3 was evaluated by dual luciferase reporter assay. The
protein levels of TIM3 were measured by western blot assay.
ResultsLnc-TIM3 was up-regulated in both cALL born
marrow and cell lines. Lnc-TIM3 knockdown down-regulated
TIM3 expression in cALL cells and remarkably restrained cALL
progression both in vitro and in vivo. The phenotypic characteristics
induced by Lnc-TIM3 knockdown were significantly reversed by
miR-5094 inhibitor, and the downstream pathway was the TIM3/GAL9
autocrine stimulatory loop. ConclusionLnc-TIM3 can
sponge miR-5094 to up-regulate the expression of TIM3,
thus promoting the development of cALL.
Bullosis Diabeticorum: Case study and literature review
Authors: Paul Axler Jean , Louis Rebecca St , Julien Adonai Aly Isaac , Blaise Wendell
Published: January 2023

Bullosis Diabeticorum is a rare skin complication of diabetes mellitus.
With a prevalence ranging from 0.16% to 0.5%, it affects mostly men
with an acral and distal asymmetric presentation. We report a case of
bullous disease in a known diabetic patient associated with morbid
obesity.
Genetic characterization and Temporal dynamics of Orf virus in Small Ruminants from Republic of Niger and parts of Northern Nigeria sold in Livestock Market in Abuja
Authors: Motayo Babatunde , ONOJA Anyebe Bernard , AJAGBE Oluwaseyi , ADAMU Andrew Musa , OMATOLA Cornelius Arome , Shittu Ismaila , AJAGBE Adenike
Published: January 2023

Background: Orf virus (ORFV) is an important zoonotic parapox
virus, with 100% morbidity. It affects mainly domesticated ruminants
such as sheep and goats. This study determined the molecular
epidemiology of ORFV local as well as imported sheep and goats in
Nigeria and evolution of ORFV in Africa. Methods: A total of 30
small ruminants with orf were sampled in a livestock market Abuja
Nigeria.Skin scabs from pathological tissues were collected and
processed for viral genomic DNA. PCR and Sanger sequencing of B2L gene
of ORFV. Phylogenetic analysis, phylogeography, and Bayesian skygird
reconstruction (BSK), including mutational changes were performed on B2L
gene sequences. Results: An ORFV positivity rate of 67% was
determined from samples. Animals <2 years had the highest
prevalence of 76.5%.Hundred percent attack rate was observed among the
Uda and WAD breeds, followed by Niger 71.4%, Kano Brown 66.7%, Yankasa
25% and Balami 0% breeds. ORFV from Africa breeds clustered into 2
major lineages, Asian and African, with an evolutionary rate of 7.45 ×
10 , 95% HPD (3.46 × 10 to
1.17 × 10 ) substitutions/ site/year. Viral
population demography showed a constant population growth with a slight
rise in viral population growth towards year 2020. Conclusion:
We report molecular evolution of ORFV in Africa and identified gap in
molecular data; we recommend regional molecular surveillance of ORFV and
other zoonotic trans-boundary diseases in global health prevention and
control effort.
The Upper Airway Microbiome in Hispanic Children with Cystic Fibrosis
Authors: Palla John , Thapa Santosh , Venkatachalam Alamelu , Runge Jessica K. , Laguna Theresa , Luna Ruth Ann
Published: January 2023

Background: Hispanic people with cystic fibrosis (CF) have
decreased life expectancy and earlier acquisition of Pseudomonas
aeruginosa compared to non-Hispanic white individuals with CF. Racial
and ethnic differences in the airway microbiome of CF may contribute to
known health disparity, but have not been studied. The objective was to
describe differences in the upper airway microbial community in Hispanic
and non-Hispanic white children with CF. Methods: This
prospective, observational cohort study of fifty-nine Hispanic and
non-Hispanic white children with CF, ages 2-10 years old, was performed
at Texas Children’s Hospital (TCH) from February 2019 to January 2020.
Oropharyngeal swabs were collected from the cohort during clinic visit.
Swab samples underwent sequencing (16S V4 rRNA), diversity analysis, and
taxonomic profiling. Key demographic and clinical data were collected
from the electronic medical record and the Cystic Fibrosis Foundation
Patient Registry (CFFPR). Statistical analysis compared sequencing,
demographic, and clinical data. Results: We found no
significant difference in Shannon diversity or relative abundance of
bacterial phyla between Hispanic and non-Hispanic children with CF.
However, a low abundant taxa- “uncultured bacterium” belonging to the
order Saccharimonadales was significantly higher in Hispanic
children (mean relative abundance=0.13%) compared to the non-Hispanic
children (0.03%). Hispanic children had increased incidence of
Pseudomonas aeruginosa (p=0.045) compared to non-Hispanic
children. Conclusion: We did not find a significant difference
in the airway microbial diversity between Hispanic and non-Hispanic
white children with CF. However, we found a greater relative abundance
of Saccharimonadales and higher incidence of Pseudomonas
aeruginosa in Hispanic children with CF.
A Critical Study on the Researches about the Application of Neurothecnology in Education
Authors: Alibigloo Hatef Pourrashidi , Alipoor Javad
Published: January 2023

The education and pedagogy have been adopted with the growth of
technology in order to achieve efficient consequences by the usage of
innovational and up-to-date technologies. The new methods in
neuroscience and neurotechnology have influenced education and
classrooms. A considerable number of researches have been projected in
this field that all try to demonstrate the advantages of neurotechnology
in education and classrooms. In fact, most researchers have connived its
harms and disadvantages on students and learning system and the sphere
of the classrooms. This paper tries to survey on the fourteen recent
researches in the framework of critical theory to discuss the adverse
effects of neurotechnology as well as their neglected aspects in
education and the classrooms.
Boundary-layer flow of heat and mass for Tiwari-Das nanofluid model over a flat plate with variable wall temperature
Authors: Bao Han-Xiang , Arain Muhammad , Shaheen Sidra , Khan Hasan , Usman U , Inc Mustafa , Yao Shao-Wen
Published: January 2023

A numerical study of boundary-layer flow past on a moving flat plate in
nanofluid with variable wall temperature and viscous dissipation is
presented. The PDE containing model for flow phenomena are transformed to
ODE with the aid of appropriate similarity transformations. The transformed
equations are then solved numerically by using the built-in bvp4c scheme of
MATLAB. After the validation of the scheme, numerical solutions are
determined for the temperature and nanoparticle concentration profiles along
with physical quantities of interest. The effects of involved parameters
such as variable temperature index, Prandtl number, Eckert number, Lewis
number, plate moving parameter, thermophoresis motion, and Brownian
parameters are examined and reported through graphs and tables
Estimations of accelerated generalized half-logistic distribution in presence of generalized type-II hybrid censoring samples
Authors: Abu-Zinadah Hanaa , Abd-Elmougod Gamal
Published: January 2023

Generally, the analysis of a lifetime data to quantify the life characteristics of the product done under normal conditions. The engineers for some reasons may be needed to obtain the reliability results more quickly then, accelerated life tests are applied. In this paper, we adopted partially step-stress accelerated life tests model of product has the generalized half-logistic lifetime distribution. This model is ap?plied on a solar lighting device and the stress factor consider to be temperature. Also, to save the minimum and maximum ideal test time, we applied the general?ized type-II hybrid censoring scheme. The parameters of the proposed model are estimated by maximum likelihood and Bayes methods for point and corresponding interval estimators. The validity of results is tested under formulation Monte-Carlo simulation study. The proposed model is applied on analysis data obtained from solar lighting device as real data set for illustrative purposes.
Differential diagnosis of bees nosemosis - procedure and significance
Authors: Stojanov Igor , Ratajac Radomir , Pusic Ivan
Published: January 2023

For the living world, in the existing ecosystem, for the reproduction,
production and spread of plant species, bees are one of the most important
parts of nature. In the pollination of certain field and fruit-vegetable
plant species, bees participate with almost 100%. Any factor that
contributes to reducing the presence of bees in nature, directly affects
the fertility of the plant world, and indirectly affects the rest of the
entire living population. Nosemosis is a microorganism that has a great
impact on the health of bees. In the previous period, Nosema sp. is
classified as a single-celled parasite, a protozoan, but today it is
classified as a fungus (Microsporidia). There are about 30 different species
of Nosema in nature. For the bee population, especially with regard to the
European honey bee (Apis millifera), two species of Nosema are very
important, Nosema apis and Nosema ceranae. The correct confirmation of the
type Nosema provides a better understanding of the outcomes and consequences
for the apiary in which the clinical picture of nosemosis has occurred. The
phenotypic diagnostic method, despite the present morphological differences,
does not provide the possibility of reliable confirmation of the Nosema
species. For these reasons, in order to make a differential diagnosis, it is
necessary to determine which type of Nosema is present by molecular methods.
In our work, by molecular method (PCR), we analyzed bees sampled from two
administrative areas. The examination showed that Nosema ceranae was found
in the two examined areas, while the presence of Nosema apis was not
confirmed. These results may indicate that Nosema ceranae is predominant in
the study area and has completely replaced Nosema apis.
Treatment of Molar-incisor Hypomineralization: A Case Report of 11-year Clinical Follow-up
Authors: Vieira APM , Emerenciano NG , Moda MD , Silva ÚAE , Fagundes TC , Danelon M , Cunha RF
Published: January 2023

The purpose of this case report was to describe an 11-year follow-up of a patient presenting with molar-incisor hypomineralization (MIH) having yellowish and porous permanent incisors and molars. Clinical examination revealed demarcated brown opacities on one upper and one lower central incisor and three first permanent molars. Initially, treatment involved oral hygiene and periodic fluoride varnish application. Subsequently, the occlusal surfaces of the affected molars were restored or sealed with glass ionomer cement. At-home dental bleaching was also performed. Areas of unsatisfactory esthetics on the incisors were replaced by composite resins. This report discussed the patient’s needs and expectations, the difficulties of prolonged treatment for patients with MIH, and the restorative protocol involving at-home dental bleaching and composite resins.
Arbete för flerspråkiga elever som möter svårigheter i läs- och skrivutveckling – en enkätstudie
Authors: Ylenfors Mari , Malmqvist Johan , Möllås Gunvie , Rack John
Published: January 2023

Elever med utländsk bakgrund presterar genomsnittligt lägre i läsförståelse än elever med inhemsk bakgrund. Föreliggande studie ämnar bidra med kunskap om skolors arbete med flerspråkiga elever som möter svårigheter med läsning och skrivning. Syftet med studien var att undersöka hur grundskolor i en kommun beskriver hur de arbetar med att förebygga läs- och skrivsvårigheter, identifiera läs- och skrivsvårigheter samt hur de arbetar med stödinsatser för att utveckla elevers läs- och skrivförmåga. En webbenkät skickades till samtliga skolor i en kommun. En litteracitetsmodell, som innefattar olika aspekter av läsning och skrivning med utgångspunkt i ett sociokulturellt perspektiv, användes för att analysera kodknäckande och meningsskapande undervisningspraktiker. Resultaten visar på ett behov av att utveckla skolornas arbete inom två viktiga områden. Det första är att utveckla arbetet med att tillvarata flerspråkiga elevers olika språkliga och sociokulturella resurser samt deras erfarenheter. Det andra är att förbättra samarbetet med modersmålslärare och studiehandledare. Studiens huvudslutsats är att skolor, genom att tillvarata elevers olika språkliga och kulturella resurser, rimligtvis kan förbättra stödet till flerspråkiga elever i deras läs-och skrivutveckling.
ENGLISH ABSTRACT
Schools’ teaching practices for multilingual pupils experiencing difficulties in their literacy development processThe aim of the present study is to investigate how the elementary schools in one municipality describe how they work to prevent difficulties with literacy development, to identify specific reading and writing difficulties among multilingual pupils and how they work to develop their literacy skills. A questionnaire was sent to all schools in the municipality (response rate, 77 %). A literacy model within a sociocultural theoretical framework was used in the analysis of codebreaking and meaning-making practices. The results show the need for schools to improve their capability in two crucial areas: firstly, to better utilize the students’ different linguistic resources and sociocultural experiences, and secondly to improve the collaboration with mother tongue teachers and study guidance tutors. The main conclusion is that the schools can improve their practices by taking advantage of the students’ linguistic resources to a greater extent, which plausibly can support these students’ literacy development.
Onirismo, infância e utopia na “Biografia” poética de Jorge de Lima, uma leitura do “Canto VIII”, de Invenção de Orfeu
Authors: Cavalcanti Luciano Marcos Dias
Published: January 2023

O Canto Oitavo, “Biografia”, é o maior Canto de Invenção de Orfeu, composto por apenas uma estância (em sextilhas decassílabas) retoma de maneira sintética tanto a imagética quanto a temática dos cantos anteriores. O Canto representa uma reflexão poética sobre a situação do homem desde a Queda até o Apocalipse e sua vitória final. Nele o onirismo, a infância e a imagem da ilha utópica recebem um caráter estruturante no poema. A biografia não é apenas a do poeta, abarca um sentido amplo da tradição poética, da infância como memória e criação e do desejo do encontro com uma utopia renovada, representações que podem ser consideradas o cerne de todo o épico de Jorge de Lima.
Os ensaios de Arasse
Authors: Reis Murilo Eduardo dos
Published: January 2023

O objeto de análise desta resenha é a obra Nada se vê: seis ensaios sobre pintura (2019), de Daniel Arasse. O objetivo é verificar como o historiador argelino analisa pinturas utilizando linguagem informal e misturando diferentes gêneros textuais. Além disso, é examinada a liberdade criativa que resulta em textos de alto gradiente artístico.
batalha digna de Ogum e Tupã
Authors: Pomin Fabiana , Café Lucas Santos
Published: January 2023

Este estudo analisa a inclusão da história e cultura afro-brasileira e indígena nas aulas de Educação Física, em consonância com as políticas educacionais. Observou-se a prática no Ensino Fundamental I e II e Médio, das redes municipal, estadual e federal da cidade de Primavera do Leste (MT).  Realizou-se pesquisa descritiva quanti-qualitativa, tendo como instrumento de coleta de dados questionário virtual autoaplicado; a avaliação dos resultados ocorreu por meio de leitura flutuante (com análise de conteúdo). Constatou-se que, no Município e no Estado, há uma consistente presença do conteúdo, inclusive por variados eixos. Porém, na rede federal, em que os professores atuam apenas no Ensino Médio, não há desenvolvimento da temática étnico-racial.
Apresentação do dossiê Produção e Política Cultural
Authors: Machado Sátira Pereira , Melo Alan Dutra de
Published: January 2023

Neste dossiê da Relacult apresentamos a edição temática marcando os 10 anos do Curso de Bacharelado em Produção e Política Cultural (PPC) da Universidade Federal do Pampa (Unipampa), ofertado no Campus Jaguarão – cidade do Rio Grande do Sul que faz fronteira entre o Brasil e o Uruguai, criado em 2011. Celebramos os 10 anos do Curso de Bacharelado em Produção e Política Cultural da Universidade Federal do Pampa, Campus Jaguarão, com alegria. Em tempos de ataques ao campo da cultura comemorar estes feitos realizados torna-se um ato de resistência e reconhecimento aos/às pesquisadores/as envolvidos/as nesse dossiê que compõem as edições da Revista RELACult da Editora do Centro Latino-Americano de Estudos em Cultura (CLAEC).
Integração regional e o MERCOSUL Cultural
Authors: Cruz Dayana Aparecida Marques de Oliveira
Published: January 2023

Desde 1991 os Estados Partes do MERCOSUL têm discutido questões relevantes para a integração regional no bloco. Dentre essas questões, vimos ainda nos primeiros anos após sua criação, o surgimento do MERCOSUL Cultural, que se configurou como um espaço de diálogo para a proposição de ações e iniciativas sobre cultura, patrimônio e artes entre os membros efetivos do bloco. Todavia, assim como outros órgãos e setores do MERCOSUL, o MERCOSUL Cultural, apesar de ser uma proposta inovadora, apresenta fragilidades e hiatos entre as discussões e a prática, o que revela, dentre outras coisas, a forma como os Estados nacionais lidam com as políticas culturais internas e a condução da integração regional mercosulina. O objetivo desse texto é debater sobre o papel do MERCOSUL Cultural no bloco e apresentar alguns aspectos quanto à criação, evolução e fragilidades dessa iniciativa. A metodologia utilizada foi o levantamento bibliográfico e análise de notícias disponibilizadas no site do bloco.
Apresentação
Authors: Ribeiro Angela Mara , Machado Carlos José de Azevedo
Published: January 2023

Apresentação da edição especial dos estudos apresentados  no Seminário integrador: Turismo: da Fronteira à Serra – Jaguarão – Bento Gonçalves – RS, parte do projeto do Grupo de Pesquisa Turismo, Fronteira e Desenvolvimento, registrado na UNIPAMPA e vinculado na plataforma CNpq, pela Universidade Federal do Pampa – UNIPAMPA, localizada em Jaguarão-RS fronteira com a cidade uruguaia Rio Branco. O evento é uma parceria com Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul - IFRS - Campus de Bento Gonçalves- RS.