bluuebunny/crossref_metadata_2025 huggingface dataset:
Amplitude Zone Plate in Adaptive Optics: Proposal of the Principle
Authors: Matkivsky Vasily , Moiseev Alexsandr , Shilyagin Pavel , Gelikonov Grigory
Published: March 2022

One of the main elements in hardware-based adaptive optics systems is a deformable mirror. There is quite a large number of such mirrors based on different principles and exhibiting varying performance. They constitute a significant portion of the cost of the final optical devices. In this study, we consider the possibility of replacing an adaptive mirror with the adaptive amplitude Fresnel zone plate, implemented using a digital light-processing matrix. Since such matrices are widely used in mass industry products (light projectors), their costs in large batches are 1–2 orders of magnitude lower than the cost of inexpensive deformable mirrors. Numerical modeling for scanning an optical coherence tomography system with adaptive optics is presented. It is shown that wavefront distortions with high spatial frequencies and large amplitudes can be corrected using an amplitude Fresnel zone plate. The results are compared with piezoelectric and microelectromechanical system mirrors.
Red Light and Glucose Enhance Cytokinin-Mediated Bud Initial Formation in Physcomitrium patens
Authors: Biswal Durga Prasad , Panigrahi Kishore Chandra Sekhar
Published: March 2022

Growth and development of Physcomitrium patens is endogenously regulated by phytohormones such as auxin and cytokinin. Auxin induces the transition of chloronema to caulonema. This transition is also regulated by additional factors such as quantity and quality of light, carbon supply, and other phytohormones such as strigolactones and precursors of gibberrelic acid. On the other hand, cytokinins induce the formation of bud initials following caulonema differentiation. However, the influence of external factors such as light or nutrient supply on cytokinin-mediated bud initial formation has not been demonstrated in Physcomitrium patens. This study deals with the effect of light quality and nutrient supply on cytokinin-mediated bud initial formation. Bud initial formation has been observed in wild type plants in different light conditions such as white, red, and blue light in response to exogenously supplied cytokinin as well as glucose. In addition, budding assay has been demonstrated in the cry1a mutant of Physcomitrium in different light conditions. The results indicate that carbon supply and red light enhance the cytokinin response, while blue light inhibits this process in Physcomitrium.
Waterlogged Conditions Influence the Nitrogen, Phosphorus, Potassium, and Sugar Distribution in Sago Palm (Metroxylon sagu Rottb.) at Seedling Stages
Authors: Azhar Aidil , Asano Koki , Sugiura Daisuke , Kano-Nakata Mana , Ehara Hiroshi
Published: March 2022

Sago palm (Metroxylon sagu Rottb.) grows in well-drained mineral soil and in peatland with high groundwater levels until complete submersion. However, the published information on nutrient uptake and carbohydrate content in sago palms growing under waterlogging remains unreported. This experiment observed sago palm growth performance under normal soil conditions (non-submerged conditions) as a control plot and extended waterlogged conditions. Several parameters were analyzed: Plant morphological growth traits, nitrogen, phosphorus, potassium, and sugar concentration in the plant organ, including sucrose, glucose, starch, and non-structural carbohydrate. The analysis found that sago palm morphological growth traits were not significantly affected by extended waterlogging. However, waterlogging reduced carbohydrate levels in the upper part of the sago palm, especially the petiole, and increased sugar levels, especially glucose, in roots. Waterlogging also reduced N concentration in roots and leaflets and P in petioles. The K level was independent of waterlogging as the sago palm maintained a sufficient level in all of the plant organs. Long duration waterlogging may reduce the plant’s economic value as the starch level in the trunk decreases, although sago palm can grow while waterlogged.
Genome-Wide Identification and Expression Analysis of SNARE Genes in Brassica napus
Authors: Xu Jing , Zhao Xu , Bao Jiandong , Shan Yanan , Zhang Mengjiao , Shen Yanan , Abubakar Yakubu Saddeeq , Lu Guodong , Wang Zonghua , Wang Airong
Published: March 2022

SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are central components that drive membrane fusion events during exocytosis and endocytosis and play important roles in different biological processes of plants. In this study, we identified 237 genes encoding SNARE family proteins in B. napus in silico at the whole-genome level. Phylogenetic analysis showed that BnaSNAREs could be classified into five groups (Q (a-, b-, c-, bc-) and R) like other plant SNAREs and clustered into twenty-five subclades. The gene structure and protein domain of each subclade were found to be highly conserved. In many subclades, BnaSNAREs are significantly expanded compared with the orthologous genes in Arabidopsis thaliana. BnaSNARE genes are expressed differentially in the leaves and roots of B. napus. RNA-seq data and RT-qPCR proved that some of the BnaSNAREs are involved in the plant response to S. sclerotiorum infection as well as treatments with toxin oxalic acid (OA) (a virulence factor often secreted by S. sclerotiorum) or abscisic acid (ABA), methyl jasmonate (MeJA), and salicylic acid (SA), which individually promote resistance to S. sclerotiorum. Moreover, the interacted proteins of BnaSNAREs contain some defense response-related proteins, which increases the evidence that BnaSNAREs are involved in plant immunity. We also found the co-expression of BnaSYP121/2s, BnaSNAPs, and BnaVAMP722/3s in B. napus due to S. sclerotiorum infection as well as the probable interaction among them.
Proteomic Profiling and Rhizosphere-Associated Microbial Communities Reveal Adaptive Mechanisms of Dioclea apurensis Kunth in Eastern Amazon’s Rehabilitating Minelands
Authors: Nascimento Sidney Vasconcelos do , Costa Paulo Henrique de Oliveira , Herrera Hector , Caldeira Cecílio Frois , Gastauer Markus , Ramos Silvio Junio , Oliveira Guilherme , Valadares Rafael Borges da Silva
Published: March 2022

Dioclea apurensis Kunth is native to ferruginous rocky outcrops (known as canga) in the eastern Amazon. Native cangas are considered hotspots of biological diversity and have one of the largest iron ore deposits in the world. There, D. apurensis can grow in post-mining areas where molecular mechanisms and rhizospheric interactions with soil microorganisms are expected to contribute to their establishment in rehabilitating minelands (RM). In this study, we compare the root proteomic profile and rhizosphere-associated bacterial and fungal communities of D. apurensis growing in canga and RM to characterize the main mechanisms that allow the growth and establishment in post-mining areas. The results showed that proteins involved in response to oxidative stress, drought, excess of iron, and phosphorus deficiency showed higher levels in canga and, therefore, helped explain its high establishment rates in RM. Rhizospheric selectivity of microorganisms was more evident in canga. The microbial community structure was mostly different between the two habitats, denoting that despite having its preferences, D. apurensis can associate with beneficial soil microorganisms without specificity. Therefore, its good performance in RM can also be improved or attributed to its ability to cope with beneficial soil-borne microorganisms. Native plants with such adaptations must be used to enhance the rehabilitation process.
Genus Salsola: Chemistry, Biological Activities and Future Prospective—A Review
Authors: Murshid Samar S. A. , Atoum Dana , Abou-Hussein Dina R. , Abdallah Hossam M. , Hareeri Rawan H. , Almukadi Haifa , Edrada-Ebel RuAngelie
Published: March 2022

The genus Salsola L. (Russian thistle, Saltwort) includes halophyte plants and is considered one of the largest genera in the family Amaranthaceae. The genus involves annual semi-dwarf to dwarf shrubs and woody tree. The genus Salsola is frequently overlooked, and few people are aware of its significance. The majority of studies focus on pollen morphology and species identification. Salsola has had little research on its phytochemical makeup or biological effects. Therefore, we present this review to cover all aspects of genus Salsola, including taxonomy, distribution, differences in the chemical constituents and representative examples of isolated compounds produced by various species of genus Salsola and in relation to their several reported biological activities for use in folk medicine worldwide.
The Specificity of Transgene Suppression in Plants by Exogenous dsRNA
Authors: Kiselev Konstantin V. , Suprun Andrey R. , Aleynova Olga A. , Ogneva Zlata V. , Kostetsky Eduard Y. , Dubrovina Alexandra S.
Published: March 2022

The phenomenon of RNA interference (RNAi) is widely used to develop new approaches for crop improvement and plant protection. Recent investigations show that it is possible to downregulate plant transgenes, as more prone sequences to silencing than endogenous genes, by exogenous application of double-stranded RNAs (dsRNAs) and small interfering RNAs (siRNAs). However, there are scarce data on the specificity of exogenous RNAs. In this study, we explored whether plant transgene suppression is sequence-specific to exogenous dsRNAs and whether similar effects can be caused by exogenous DNAs that are known to be perceived by plants and induce certain epigenetic and biochemical changes. We treated transgenic plants of Arabidopsis thaliana bearing the neomycin phosphotransferase II (NPTII) transgene with specific synthetic NPTII-dsRNAs and non-specific dsRNAs, encoding enhanced green fluorescent protein (EGFP), as well as with DNA molecules mimicking the applied RNAs. None of the EGFP-dsRNA doses resulted in a significant decrease in NPTII transgene expression in the NPTII-transgenic plants, while the specific NPTII-dsRNA significantly reduced NPTII expression in a dose-dependent manner. Long DNAs mimicking dsRNAs and short DNA oligonucleotides mimicking siRNAs did not exhibit a significant effect on NPTII transgene expression. Thus, exogenous NPTII-dsRNAs induced a sequence-specific and RNA-specific transgene-suppressing effect, supporting external application of dsRNAs as a promising strategy for plant gene regulation.
Salt Stress in Plants and Mitigation Approaches
Authors: Ondrasek Gabrijel , Rathod Santosha , Manohara Kallakeri Kannappa , Gireesh Channappa , Anantha Madhyavenkatapura Siddaiah , Sakhare Akshay Sureshrao , Parmar Brajendra , Yadav Brahamdeo Kumar , Bandumula Nirmala , Raihan Farzana , Zielińska-Chmielewska Anna , Meriño-Gergichevich Cristian , Reyes-Díaz Marjorie , Khan Amanullah , Panfilova Olga , Seguel Fuentealba Alex , Romero Sebastián Meier , Nabil Beithou , Wan Chunpeng (Craig) , Shepherd Jonti , Horvatinec Jelena
Published: March 2022

Salinization of soils and freshwater resources by natural processes and/or human activities has become an increasing issue that affects environmental services and socioeconomic relations. In addition, salinization jeopardizes agroecosystems, inducing salt stress in most cultivated plants (nutrient deficiency, pH and oxidative stress, biomass reduction), and directly affects the quality and quantity of food production. Depending on the type of salt/stress (alkaline or pH-neutral), specific approaches and solutions should be applied to ameliorate the situation on-site. Various agro-hydrotechnical (soil and water conservation, reduced tillage, mulching, rainwater harvesting, irrigation and drainage, control of seawater intrusion), biological (agroforestry, multi-cropping, cultivation of salt-resistant species, bacterial inoculation, promotion of mycorrhiza, grafting with salt-resistant rootstocks), chemical (application of organic and mineral amendments, phytohormones), bio-ecological (breeding, desalination, application of nano-based products, seed biopriming), and/or institutional solutions (salinity monitoring, integrated national and regional strategies) are very effective against salinity/salt stress and numerous other constraints. Advances in computer science (artificial intelligence, machine learning) provide rapid predictions of salinization processes from the field to the global scale, under numerous scenarios, including climate change. Thus, these results represent a comprehensive outcome and tool for a multidisciplinary approach to protect and control salinization, minimizing damages caused by salt stress.
Effect of Organic Manure and Moisture Regimes on Soil Physiochemical Properties, Microbial Biomass Cmic:Nmic:Pmic Turnover and Yield of Mustard Grains in Arid Climate
Authors: Bhanwaria Rajendra , Singh Bikarma , Musarella Carmelo Maria
Published: March 2022

(1) Background: Arid conditions occur due to climate abnormality in the different biogeography regions of the world. The aim of this research is to investigate the stoichiometry of manure and moisture regimes on soil properties, microbial biomass C:N:P turnover, and the grain yield of mustard crops under stress in arid conditions; (2) Methods: The field experiment was carried out for 2 years at the farms of the agriculture college of SKN, Jobner (SKRAU Bikaner, Rajasthan). The effects of organic manure, moisture regimes, and saline water treatment on soil properties, such as the soil microbial biomass build-up, loss, turnover, and recycling of carbon (Cmic), nitrogen (Nmic), and phosphorus (Pmic) in the mustard crop were investigated. The twenty-seven treatments studied are described as follows: organic manures (control, FYM @ 10 t ha−1 and vermicompost @ 5 t ha−1), moisture regimes (0.4, 0.6, and 0.8 IW/CPE ratio), and saline irrigation water (control, 6, 12 dSm−1); (3) Results: Our findings indicate that vermicompost @ 5 t ha−1 significantly increases moisture retention and the available water in soil at 33 kPa and 1500 kPa. The microbial biomass build-up of Cmic increases by 43.13% over the control and 14.36% over the FYM. Similarly, the soil microbial biomass of Nmic, and Pmic also increase considerably. The SHC of the soil is enhanced by the application of farmyard fertilizer and vermicompost. The BD and pH decrease significantly, while the SHC, OC, CEC, and ECe of the soil increase significantly. The build-up, losses, and fluxes of the soil microbial biomass of Cmic, Nmic, and Pmic increase significantly, and the turnover rate decreases under vermicompost @ 5 t ha−1. A significant increase in grain yield was observed. Irrigation with a 0.8 IW/CPE moisture regime significantly decreases the pH of the SHC; (4) Conclusions: We hypothesized the interactive outcomes of the moisture regime and found that organic manure significantly influenced grain and stover yield. The treatments of quality irrigation water and the addition of organic manure are efficient enough to improve soil properties, water holding capacity, and soil microbial biomass C:N:P in stress climatic conditions.
A Systematic Map of the Research on Disease Modelling for Agricultural Crops Worldwide
Authors: Fedele Giorgia , Brischetto Chiara , Rossi Vittorio , Gonzalez-Dominguez Elisa
Published: March 2022

In this work, we developed a systematic map to identify and catalogue the literature pertaining to disease modelling for agricultural crops worldwide. Searches were performed in 2021 in the Web of Science and Scopus for papers reporting any type of disease model for 103 crops. In total, 768 papers were retrieved, and their descriptive metadata were extracted. The number of papers found increased from the mid-1900s to 2020, and most of the studies were from North America and Europe. More disease models were retrieved for wheat, potatoes, grapes, and apples than for other crops; the number of papers was more affected by the crop’s economic value than by its cultivated area. The systematic map revealed an underrepresentation of disease models for maize and rice, which is not justified by either the crop economic value or by disease impact. Most of the models were developed to understand the pathosystem, and fewer were developed for tactical disease management, strategic planning, or scenario analysis. The systematic map highlights a variety of knowledge gaps and suggests questions that warrant further research.
Experimental Investigation of Vitrification Process for the Disposal of Hazardous Solid Waste Containing Chlorides
Authors: Hu Yihang , Chen Ziwei , Jiao Yang , Chen Weibin , Liu Lili , Wang Xidong
Published: March 2022

Vitrification has attracted much attention as an efficient method for solidifying heavy metals in hazardous solid wastes, but its effect is limited when hazardous solid wastes contain chlorides. Aiming at fly ash, a normal chlorine-containing solid waste, a novel process of chlorination melting and glass curing was developed to completely realize the harmlessness of heavy metals. Melting temperature, time, and auxiliary agent were adequate to realize the harmlessness, and their influence on the migration and transformation of Cl, Na, Pb, and Zn and the leaching of slag were studied. The results showed that the majority of Cl, Na, Pb, and Zn in the fly ash had been transferred to the soot, and the residual part in the slag had been solidified in glass by controlling the process conditions. Under the optimized conditions (12 wt.% CaO and 5 wt.% SiO2 was added, the N2 flow ratio was at 1 L/min, and the melting temperature was 1300 °C for 2 h), the leaching index was determined, including the acid dissolution ratio, the Pb and Zn content of the water leaching solution, and the acid leaching solution, which all met the requirements of the relevant standards. Furthermore, the novel process provided a simple and efficient approach for the disposal of other similar solid wastes containing chlorides and heavy metals.
Numerical Study for Determining the Strength Limits of a Powered Longwall Support
Authors: Szurgacz Dawid , Trzop Konrad , Gil Jan , Zhironkin Sergey , Pokorný Jiří , Gondek Horst
Published: March 2022

The process of designing a longwall powered support is extremely complex and requires many operations related to the creation of a complete machine. The powered support section is one of the basic elements of the longwall system. It acts as protection for the working space and takes part in the process of excavating and transporting the spoil. The implementation of the support that meets the guidelines of the manufacturer and user requires an endurance analysis at the design stage conducted according to the regulations in force. The main objective of this research, pursued by the authors, was to perform the analysis of the ultimate strength of selected elements of the designed powered support section. The research was carried out with the use of special software that uses the finite element method. This article presents the analysis of the strength limits conducted with the help of the finite element method, determining the strength of selected elements of the longwall support section. The solutions proposed by the authors include changes in the structure and properties of the material in the design process. The aim of the proposed solution was to obtain a model with strength value that meets safety standards. The research results are a valuable source of knowledge for designers. Solutions of this type set examples for spatial models of the longwall support section being designed currently. The analysis presented in the article, together with the results of the research and the conclusions resulting from them, may improve the safety and effectiveness of powered supports.
Challenging Sustainable and Innovative Technologies in Cheese Production: A Review
Authors: Oštarić Fabijan , Antunac Neven , Cubric-Curik Vlatka , Curik Ino , Jurić Slaven , Kazazić Snježana , Kiš Marta , Vinceković Marko , Zdolec Nevijo , Špoljarić Jasminka , Mikulec Nataša
Published: March 2022

It is well known that cheese yield and quality are affected by animal genetics, milk quality (chemical, physical, and microbiological), production technology, and the type of rennet and dairy cultures used in production. Major differences in the same type of cheese (i.e., hard cheese) are caused by the rennet and dairy cultures, which affect the ripening process. This review aims to explore current technological advancements in animal genetics, methods for the isolation and production of rennet and dairy cultures, along with possible applications of microencapsulation in rennet and dairy culture production, as well as the challenge posed to current dairy technologies by the preservation of biodiversity. Based on the reviewed scientific literature, it can be concluded that innovative approaches and the described techniques can significantly improve cheese production.
Multi-Phase In Silico Discovery of Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors among 3009 Clinical and FDA-Approved Related Drugs
Authors: Elkaeed Eslam B. , Elkady Hazem , Belal Amany , Alsfouk Bshra A. , Ibrahim Tuqa H. , Abdelmoaty Mohamed , Arafa Reem K. , Metwaly Ahmed M. , Eissa Ibrahim H.
Published: March 2022

Proceeding our prior studies of SARS-CoV-2, the inhibitory potential against SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) has been investigated for a collection of 3009 clinical and FDA-approved drugs. A multi-phase in silico approach has been employed in this study. Initially, a molecular fingerprint experiment of Remdesivir (RTP), the co-crystallized ligand of the examined protein, revealed the most similar 150 compounds. Among them, 30 compounds were selected after a structure similarity experiment. Subsequently, the most similar 30 compounds were docked against SARS-CoV-2 RNA-dependent RNA polymerase (PDB ID: 7BV2). Aloin 359, Baicalin 456, Cefadroxil 1273, Sophoricoside 1459, Hyperoside 2109, and Vitexin 2286 exhibited the most precise binding modes, as well as the best binding energies. To confirm the obtained results, MD simulations experiments have been conducted for Hyperoside 2109, the natural flavonoid glycoside that exhibited the best docking scores, against RdRp (PDB ID: 7BV2) for 100 ns. The achieved results authenticated the correct binding of 2109, showing low energy and optimum dynamics. Our team presents these outcomes for scientists all over the world to advance in vitro and in vivo examinations against COVID-19 for the promising compounds.
Modeling and Optimal Control of an Electro-Fermentation Process within a Batch Culture
Authors: Haidar Ihab , Desmond-Le Quéméner Elie , Barbot Jean-Pierre , Harmand Jérôme , Rapaport Alain
Published: March 2022

Electro-fermentation is a novel process that consists in coupling a microbial fermentative metabolism with an electrochemical system. In such a process, the electrodes act either as the electron sinks or sources modifying the fermentation balance of a microbial fermentative metabolism and provide new options for the control of microbial activity. A theoretical framework for the analysis and control of fermentations using electro-fermentation is currently lacking. In this paper, we propose a simple electro-fermentation model in which a population of fermentative bacteria switch between two metabolic behaviors in response to different electrode potentials. We then mathematically analyze optimal strategies to maximize the production of one of the rising products in a batch fermentation using Pontryagin’s Maximum Principle. The obtained results show that, in some experimental configurations, a dynamic control of the electrode potential is required for the maximization of the desired product. Consequences of the obtained optimal strategy for driving electro-fermentation experiments are discussed through a realistic example. This analysis also highlights that the transition rates between fermentation and electro-fermentation behaviors are currently unknown and would be crucial to quantify in order to apply such a control approach.
On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review
Authors: Catalano Chiara , Pasta Salvatore
Published: March 2022

Transcatheter aortic valve replacement (TAVR) has become a milestone for the management of aortic stenosis in a growing number of patients who are unfavorable candidates for surgery. With the new generation of transcatheter heart valves (THV), the feasibility of transcatheter mitral valve replacement (TMVR) for degenerated mitral bioprostheses and failed annuloplasty rings has been demonstrated. In this setting, computational simulations are modernizing the preoperative planning of transcatheter heart valve interventions by predicting the outcome of the bioprosthesis interaction with the human host in a patient-specific fashion. However, computational modeling needs to carry out increasingly challenging levels including the verification and validation to obtain accurate and realistic predictions. This review aims to provide an overall assessment of the recent advances in computational modeling for TAVR and TMVR as well as gaps in the knowledge limiting model credibility and reliability.
Optimized Clinical Strategies for Treatment-Resistant Depression: Integrating Ketamine Protocols with Trauma- and Attachment-Informed Psychotherapy
Authors: Muscat Sherry-Anne , Hartelius Glenn , Crouch Courtenay Richards , Morin Kevin W.
Published: March 2022

Strategically timed trauma- and attachment-informed psychotherapy to address underlying emotional wounds, paired with ketamine administered in precision-calibrated doses to ensure high-entropy brain states, may be key to improving the quality and duration of ketamine’s therapeutic efficacy for treatment-resistant depression. This approach optimizes the opportunities for change created by ketamine’s known effects as a rapid antidepressant that stimulates synaptogenesis, normalizes neural connectivity and coherence, enhances neuroplasticity, reduces inflammation, and induces high-entropy brain states with associated subjective psychedelic experiences. Ketamine, a non-selective N-methyl-D-aspartate (NMDA) receptor antagonist is a safe, effective, fast-acting dissociative anesthetic that, as a standalone treatment, also exhibits rapid sustained antidepressant effects, even in many patients with treatment-resistant depression. A prior history of developmental trauma and attachment injuries are known primary factors in the etiology of treatment resistance in depression and other mental disorders. Thus, the adjunct of targeted psychotherapy attuned to trauma and attachment injuries may enhance and prolong ketamine efficacy and provide an opportunity for lasting therapeutic change. Psychotherapy engagement during repeated ketamine sessions for patient safety and integration of altered states, paired with separate individualized psychotherapy-only sessions timed 24–48 h post ketamine induction, takes advantage of peak ketamine-induced dendritic spine growth in the prefrontal cortex and limbic system, and normalized network connectivity across brain structures. This strategically timed paired-session approach also exploits the therapeutic potential created by precision-calibrated ketamine-linked high-entropy brain states and associated psychedelic experiences that are posited to disrupt overly rigid maladaptive thoughts, behaviors, and disturbing memories associated with treatment-resistant depression; paired sessions also support integration of the felt sense of happiness and connectivity associated with psychedelic experiences.
Characteristics and Use Patterns of Outdoor Recreationists on Public Lands in Alabama—Case Study of Bankhead National Forest and Sipsey Wilderness Area
Authors: Christian Colmore S. , Scott Chelsea N.
Published: March 2022

Like many other states in south-east USA, Alabama is blessed with a high percentage of natural areas. These areas support vital nature tourism and the outdoor recreation sector. This study was undertaken at the Bankhead National Forest (BNF) and Sipsey Wilderness Area (SWA), significant hubs for outdoor recreation in northwestern Alabama. The goal of this study was to collect baseline information that could be used to develop tools and strategies for increasing the diversity of users participating in outdoor recreation at BNF/SWA. A pretested questionnaire was administered to visitors at eight outdoor recreation sites in the BNF/SWA. Adults encountered at study locations were invited, after their visit, to participate in the study. The study found that (a) the majority of visitors to the BNF/SWA were Caucasians and the least encountered race was African American; (b) the most common reason for visiting BNF/SWA was for family outings, whereas activities with friends or coworkers were the second most important reason for visiting; (c) hiking (39.6%), camping (29.1%), picnicking (23.3%), and horseback riding (22.5%) were the most popular outdoor recreation activities pursued by visitors. It was concluded that a study aimed at identifying the constraints which negatively impact the use of the BNF/SWA by minorities should be a critical step in the process of trying to diversify the BNF/SWA’s user base. Increased efforts must be made to identify the reasons for the low usage of the BNF/SWA by minorities.
Efficient Depth Fusion Transformer for Aerial Image Semantic Segmentation
Authors: Yan Li , Huang Jianming , Xie Hong , Wei Pengcheng , Gao Zhao
Published: March 2022

Taking depth into consideration has been proven to improve the performance of semantic segmentation through providing additional geometry information. Most existing works adopt a two-stream network, extracting features from color images and depth images separately using two branches of the same structure, which suffer from high memory and computation costs. We find that depth features acquired by simple downsampling can also play a complementary part in the semantic segmentation task, sometimes even better than the two-stream scheme with the same two branches. In this paper, a novel and efficient depth fusion transformer network for aerial image segmentation is proposed. The presented network utilizes patch merging to downsample depth input and a depth-aware self-attention (DSA) module is designed to mitigate the gap caused by difference between two branches and two modalities. Concretely, the DSA fuses depth features and color features by computing depth similarity and impact on self-attention map calculated by color feature. Extensive experiments on the ISPRS 2D semantic segmentation dataset validate the efficiency and effectiveness of our method. With nearly half the parameters of traditional two-stream scheme, our method acquires 83.82% mIoU on Vaihingen dataset outperforming other state-of-the-art methods and 87.43% mIoU on Potsdam dataset comparable to the state-of-the-art.
Degraded States of Engagement in Air Traffic Control
Authors: Migliorini Yannick , Imbert Jean-Paul , Roy Raphaëlle N. , Lafont Alex , Dehais Frédéric
Published: March 2022

Safety studies have identified attention as a recurring cause of incidents and accidents in air traffic control. However, little is known of the precise attentional states that lead to degraded ATC performance. Therefore, we surveyed 150 French en route air traffic controllers on the causes of and impacts on perceived cooperation, safety, and performance of seven degraded attentional states from the literature: task-related and task-unrelated mind wandering, mental overload, inattentional deafness and blindness, attentional entropy, and perseveration. Our findings indicated that task-related and task-unrelated mind wandering were the most prevalent but had the least impact on perceived safety. Conversely, inattentional blindness and attentional entropy were less reported but were considered a significant safety concern, while inattentional deafness affected cooperation. Most states were experienced in workload levels consistent with the literature. However, no other factor such as shift work was identified as a cause of these states. Overall, these findings suggest that “attention” is not a specific enough subject for ATC, as attentional issues can occur in various conditions and have different impacts. As far as safety is concerned, inattentional blindness should be the prime target for further research. Neuroergonomics in particular could help develop dynamic countermeasures to mitigate its impact.
Effect of the Reduction in Training Volume during the COVID-19 Era on Performance in 100-m and 400-m Freestyle Events in Greek Swimming Championships
Authors: Tsalis George , Mougios Vassilis
Published: March 2022

The COVID-19 pandemic had a profound impact on almost all social activities, including sport participation. Swimming training was greatly reduced during the 2019–2020 and 2020–2021 seasons (by four and two months, respectively), which caused athletes and coaches to worry about performance in championships. The present study investigated the impact of COVID-19 lockdowns on the results of Greek swimming championships in the categories of 13 to 18 years of age during 2020 and 2021. Forty-one coaches were interviewed about the training process (satisfaction, duration of the training season, and daily training swimming distance), and the performance of swimmers in national championships over seven seasons (2014–2021) was analyzed. The duration of the training season and the daily swimming distance, as reported by the coaches, were lower during the 2019–2020 and 2020–2021 seasons, compared to the previous five seasons (p < 0.001). The number of swimmers who achieved qualifying times for the national championships during the COVID-19 era were similar to those in previous years. Comparisons of the times in the 100-m and 400-m freestyle events, in both genders, from 2015 through 2021, showed no significant differences except for the 400-m event in males, in which a lower performance was detected in 2021 compared to 2015 (by 2.7%, p = 0.001). In conclusion, two or four months of detraining during the COVID-19 era had a negative impact on the coaches’ evaluation of the training process, but there was no effect on the number of young swimmers who qualified for the national championships and a negligible effect on swimming performance in 100-m and 400-m freestyle events.
Effects of Unilateral Muscle Fatigue on Thermographic Skin Surface Temperature of Back and Abdominal Muscles—A Pilot Study
Authors: Dindorf Carlo , Bartaguiz Eva , Janowicz Elena , Fröhlich Michael , Ludwig Oliver
Published: March 2022

The present study aimed to assess the effects of asymmetric muscle fatigue on the skin surface temperature of abdominal and back muscles. The study was based on a pre-post/follow-up design with one group and included a total of 41 subjects (22 male, 19 female; age, 22.63 ± 3.91; weight, 71.89 ± 12.97 kg; height, 173.36 ± 9.95). All the participants were asked to perform side bends in sets of 20 repetitions on a Roman chair until complete exhaustion. The pre-, post- and follow-up test (24 h after) skin surface temperatures were recorded with infrared thermography. Subjective muscle soreness and muscle fatigue were analyzed using two questionnaires. The results of the post hoc tests showed that skin temperature was statistically significantly lower in the post-tests than in the pre- and follow-up tests, but no meaningful differences existed between the pre- and follow-up tests. Asymmetric side differences were found in the post-test for the upper and lower areas of the back. Differences were also noted for the front in both the upper and lower areas. No thermographic side asymmetries were found at the pre- or follow-up measurement for either the back or the front. Our results support the potential of using thermographic skin surface temperature to monitor exercise and recovery in athletes, as well as its use in rehabilitational exercise selection.
Power Differences and Dynamics in Multiparty Collaborative Systems: A Systematic Literature Review
Authors: Trif Sabina Ramona , Curșeu Petru Lucian , Fodor Oana Cătălina
Published: March 2022

This paper presents the results of a systematic literature review on power distribution and power dynamics in multiparty systems. Multiparty systems are underorganized social structures in which power dynamics unfold and impact collaboration effectiveness. We use a theory-driven approach to integrate the empirical literature that explored power differences and dynamics in multiparty systems and we have a two-fold contribution to literature. First, we explore the way power is conceptualized in multiparty systems. Second, we investigate which predictions and propositions of the Social Distance Theory of Power and the Approach Inhibition Model of Power can be used to integrate research on power distribution and dynamics in multiparty systems. We extend the predominantly experimental empirical support of these two theories with insights from the multiparty systems literature. With respect to the way in which power is conceptualized in the multiparty systems literature, our study shows a shift from a possession over resources to a relational perspective on power in the last decades. Moreover, based on the insights of the two psychological theories of power, the study reflects upon the benefits and drawbacks of high versus low power for collaboration effectiveness among stakeholders, pointing towards ways in which facilitators can work with power differences in multiparty systems. Finally, the study points toward directions for future research concerning power dynamics in multiparty systems.
Artificial Digestion of Polydisperse Copper Oxide Nanoparticles: Investigation of Effects on the Human In Vitro Intestinal Co-Culture Model Caco-2/HT29-MTX
Authors: Büttner Jevin , Schneider Thomas , Westermann Martin , Glei Michael
Published: March 2022

Copper oxide nanoparticles (CuO-NP) are increasingly used in consumer-related products, which may result in increased oral ingestion. Digestion of particles can change their physicochemical properties and toxicity. Therefore, our aim was to simulate the gastrointestinal tract using a static in vitro digestion model. Toxic properties of digested and undigested CuO-NP were compared using an epithelial mono-culture (Caco-2) and a mucus-secreting co-culture model (Caco-2/HT29-MTX). Effects on intestinal barrier integrity, permeability, cell viability and apoptosis were analyzed. CuO-NP concentrations of 1, 10 and 100 µg mL−1 were used. Particle characterization by dynamic light scattering and transmission electron microscopy showed similar mean particle sizes before and after digestion, resulting in comparable delivered particle doses in vitro. Only slight effects on barrier integrity and cell viability were detected for 100 µg mL−1 CuO-NP, while the ion control CuCl2 always caused significantly higher adverse effects. The utilized cell models were not significantly different. In summary, undigested and digested CuO-NP show comparable effects on the mono-/co-cultures, which are weaker than those of copper ions. Only in the highest concentration, CuO-NP showed weak effects on barrier integrity and cell viability. Nevertheless, a slightly increased apoptosis rate indicates existing cellular stress, which gives reason for further investigations.
In Vitro Neurotoxicity of Flumethrin Pyrethroid on SH-SY5Y Neuroblastoma Cells: Apoptosis Associated with Oxidative Stress
Authors: Barrios-Arpi Luis , Arias Yurie , Lopez-Torres Bernardo , Ramos-Gonzalez Mariella , Ticli Giulio , Prosperi Ennio , Rodríguez José-Luis
Published: March 2022

Pyrethroids are neurotoxicants for animals, showing a pattern of toxic action on the nervous system. Flumethrin, a synthetic pyrethroid, is used against ectoparasites in domestic animals, plants, and for public health. This compound has been shown to be highly toxic to bees, while its effects on other animals have been less investigated. However, in vitro studies to evaluate cytotoxicity are scarce, and the mechanisms associated with this effect at the molecular level are still unknown. This study aimed to investigate the oxidative stress and cell death induction in SH-SY5Y neuroblastoma cells in response to flumethrin exposure (1–1000 µM). Flumethrin induced a significant cytotoxic effect, as evaluated by MTT and LDH leakage assays, and produced an increase in the biomarkers of oxidative stress as reactive oxygen species and nitric oxide (ROS and NO) generation, malondialdehyde (MDA) concentration, and caspase-3 activity. In addition, flumethrin significantly increased apoptosis-related gene expressions (Bax, Casp-3, BNIP3, APAF1, and AKT1) and oxidative stress and antioxidative (NFκB and SOD2) mediators. The results demonstrated, by biochemical and gene expression assays, that flumethrin induces oxidative stress and apoptosis, which could cause DNA damage. Detailed knowledge obtained about these molecular changes could provide the basis for elucidating the molecular mechanisms of flumethrin-induced neurotoxicity.
Evaluation of Zebrafish DNA Integrity after Individual and Combined Exposure to TiO2 Nanoparticles and Lincomycin
Authors: Mottola Filomena , Iovine Concetta , Santonastaso Marianna , Carfora Vincenzo , Pacifico Severina , Rocco Lucia
Published: March 2022

Environmental contamination by nanoparticles (NPs) and drugs represents one of the most debated issues of the last years. The aquatic biome and, indirectly, human health are strongly influenced by the negative effects induced by the widespread presence of pharmaceutical products in wastewater, mainly due to the massive use of antibiotics and inefficient treatment of the waters. The present study aimed to evaluate the harmful consequences due to exposure to antibiotics and NPs, alone and in combination, in the aquatic environment. By exploiting some of their peculiar characteristics, such as small size and ability to bind different types of substances, NPs can carry drugs into the body, showing potential genotoxic effects. The research was conducted on zebrafish (Danio rerio) exposed in vivo to lincomycin (100 mg/L) and titanium dioxide nanoparticles (TiO2 NPs) (10 µg/L) for 7 and 14 exposure days. The effects on zebrafish were evaluated in terms of cell viability, DNA fragmentation, and genomic template stability (GTS%) investigated using Trypan blue staining, TUNEL assay, and the random amplification of polymorphic DNA PCR (RAPD PCR) technique, respectively. Our results show that after TiO2 NPs exposure, as well as after TiO2 NPs and lincomycin co-exposure, the percentage of damaged DNA significantly increased and cell viability decreased. On the contrary, exposure to lincomycin alone caused only a GTS% reduction after 14 exposure days. Therefore, the results allow us to assert that genotoxic effect in target cells could be through a synergistic effect, also potentially mediated by the establishment of intermolecular interactions between lincomycin and TiO2 NPs.
Studying ΔL = 2 Lepton Flavor Violation with Muons
Authors: Petrov Alexey A. , Conlin Renae , Grant Cody
Published: March 2022

Flavor violating processes in the lepton sector have highly suppressed branching ratios in the standard model. Thus, observation of lepton flavor violation (LFV) constitutes a clear indication of physics beyond the standard model (BSM). We review new physics searches in the processes that violate the conservation of lepton (muon) flavor by two units with muonia and muonium–antimuonium oscillations.
Comparison between Areas of Bone Visualization Using Radiolucent Hybrid Fixator Frames and Graphically Simulated Metallic Frames: An Ex Vivo Study
Authors: Bonardi Andrea , Rovesti Gian Luca , Martini Filippo Maria , Dondi Francesco , Benedini Davide , Barbieri Fabio
Published: March 2022

The objective of this study is to evaluate the difference between the amount of bone visible with the superimposition of a radiolucent hybrid external fixator and a graphically simulated metallic frame. Eighteen frames were applied to eighteen bone specimens. The fracture area (FA), the radiolucent area (RLA) and the radiopaque area (ROA) inside the FA were calculated for each construct on both postoperative views. The ratio between the RLA and FA and between the ROA and FA was used to evaluate the amount of bone visible in the FA with a radiolucent and a radiopaque fixator, respectively. Finally, the areas of RLA and ROA were compared using the Wilcoxon test and Friedman test to evaluate the effect of the radiolucent material on the amount of bone visible. Differences were considered significant if p < 0.5. In every specimen p was <0.5. The amount of bone visible was significantly higher with the radiolucent frame compared to the radiopaque frame. Based on the results of this study, the use of radiolucent materials can be a valuable option for external fixation, in order to decrease the radiographic interference of the frame, allowing better assessment of fracture reduction and bone healing on postoperative radiographs.
Traditional Goddess worship culture of Tamil society and its impact on cinematic screen portray of this generation
Authors: P Panbu Selvan , V Ilamparithi
Published: March 2022

The life of Ancient Tamil people was beautiful and full of emotions. They were the ones who gained great knowledge and experience from every phase of their lives. The knowledge and experience conserved, concocted and passed on in fragments by older generations. The people had begun to transform their love into worship and celebration. They preserved it in various art forms such as rhetoric, storytelling, painting, sculpture, street play, drama and literature for the future generations to know and cherish it. Different forms of media play a special role in transferring the same to people. Among these, cinema holds a pivotal space. The film captures the social structure born out of the aforementioned people's faith and conveys it through its story, shedding its light in the minds of the people. It is natural for people’s overwhelming beliefs to be reflected as stories of God and Goddesses. This article describes the worship of goddesses in literature and its relation to celebrating female actors on-screen in and by a Tamil society.
A Classification Scheme for Periodontal Diseases and Conditions
Authors: Колчанова Н.Э. , Чернявский Ю.П.
Published: March 2022

Американской академией периодонтологии (AAP) совместно c Европейской федерацией периодонтологии (EFP) была представлена классификация заболеваний и состояний тканей периодонта. Цель исследования – краткая характеристика изменений, внесенных в классификацию 1999 г. Проанализирована информация, включенная в научные обзоры, документы с описанием клинических случаев, доклады рабочих групп, которые послужили основой для разработки новой классификации. Она создавалась, опираясь на научно-доказательную базу данных, хотя в некоторых случаях материалы с низкой доказательной базой и частные мнения экспертов также были приняты во внимание. Классификация заболеваний и состояний тканей периодонта необходима как врачам-клиницистам для правильной диагностики и лечения пациентов, так и ученым-исследователям, изучающим вопросы этиологии, патогенеза и лечения заболеваний периодонта.

An organizing committee from the AAP and EFP has developed a classification scheme for periodontal diseases and conditions. The objectives of the research is to shot characteristic a change in classification scheme for periodontal diseases and conditions 1999. The authors analysed information included in the reviews, case definition papers, and consensus reports that has guided the development of the new classification. The new classification is base on the strongest available scientific evidence, lower level evidence and expert opinion were inevitably used whenever sufficient research data were unavailable. A classification scheme for periodontal diseases and conditions is necessary for clinicians to properly diagnose and treat patients as well as for scientists to investigate etiology, pathogenesis, natural history, and treatment of the diseases and conditions.