bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparative Study on the Nutritional Status of Children (6-59 months) in a World Vision Project Area and a Non-Project Area in Kathonwezi Division, Makueni District, Kenya
Authors:   University of Nairobi, Macharia Catherine W , W Kogi-Makau , Muroki NM
Published: August 2021

A cross-sectional survey was conducted in Kathonzweni division, Makueni district to assess and compare the nutritional status of children (6-59 months) drawn from households participating in a World Vision project vis-à-vis non-project area. The purpose of the study was to provide region specific data on the nutrition situation in the World Vision Project area and establish whether there is any significant difference from the non-operational area. A total of 320 households, of which 160 were from the World Vision project area each with at least a child aged between 6-59 months were randomly selected. In households with more than one child at this age category, only one child was selected. Structured questionnaires were administered to mothers or to alternative caretakers while anthropometric measurements were taken for all the children in the study households. Statistical package for Social Scientists (SPSS/PC+) computer package was used for data entry and analysis. Indices of nutritional status that is weight-for-age, height-for-age and weight-for-height were computed using the Epi-Info programme. The prevalence of stunting in the project area (46.5%) was slightly higher than among the non-project area (42.1%). A significant relationship was found between the children's age and their nutritional status based on the prevalence of wasting and of underweight (p<0.01) while nutritional status, based on stunting, was significantly associated with birth order. Overall, there was no significant difference in prevalence of stunting, wasting and underweight between the world vision project area and non-project area. However, the prevalence of stunting and underweight was higher than the national levels. It is, therefore, concluded that chronic malnutrition is a problem in the study area and age is an important determining factor. Even though World Vision Kenya has been involved in development projects in the area, there is still need for more targeted nutrition interventions by the organization.
Przemiany społeczno – demograficzne pod wpływem turystyki w strefie podmiejskiej Łodzi na przykładzie sołectwa Rosanów
Authors: Grzelak Krzysztof
Published: August 2021

Praca ukazuje zmiany społeczno – demograficzne dokonujące się pod wpływem ruchu turystycznego (użytkownicy działek letniskowych) w strefie podmiejskiej aglomeracji przemysłowej Łodzi na przykładzie obszaru jednego sołectwa.
Gulf of Mexico Coastal County Resilience to Natural Hazards
Authors: Summers Kevin , Harwell Linda , Lamper Andrea , McMillon Courtney , Buck Kyle , Smith Lisa
Published: August 2021

Using a Cumulative Resilience Screening Index (CRSI) that was developed to represent resilience to natural hazards at multiple scales for the United States, the U.S. coastal counties of the Gulf of Mexico (GOM) region of the United States are compared for resilience for these types of natural hazards. The assessment compares the domains, indicators and metrics of CRSI, addressing environmental, economic and societal aspects of resilience to natural hazards at county scales. The index was applied at the county scale and aggregated to represent states and two regions of the U.S. GOM coastline. Assessments showed county—level resilience in all GOM counties was low, generally below the U.S. average. Comparisons showed higher levels of resilience in the western GOM region while select counties in Louisiana, Mississippi and Alabama exhibited the lowest resilience (<2.0) to natural hazards. Some coastal counties in Florida and Texas represented the highest levels of resilience seen along the GOM coast. Much of this increased resilience appears to be due to higher levels of governance and broader levels of social, economic and ecological services.
Evaluation of the Efficacy of Mobility Plus® in the Management of Osteoarthritis and Joint Inflammation in Canines
Authors: Ashwath K.C. , Vishwanath G. Bhagwat , Kumar T. Santosh , Paramesh Rangesh
Published: August 2021

Background: Joint health is very vital in canines. Immediate attention and diagnosis will help to prevent suffering in canines. This study was designed to evaluate the in vivo efficacy of the poly-herbal formulation Mobility Plus® for arthritis, inflammation and analgesic activities in canines. Methods: A total of 18 client-owned dogs with a history of joint inflammation, hip dysplasia and arthritis were selected (n = 18) and supplemented with one tablet of Mobility Plus® daily until complete recovery. The changes in assessment parameters scores, viz. lameness score, joint mobility score, pain on palpation score, weight-bearing score and the overall clinical condition score were evaluated. The results revealed that lameness, joint mobility, pain and weight-bearing scores significantly (p less than 0.001) decreased in dogs as early as day 15; hence, the overall clinical condition score also decreased significantly (p less than 0.001) as early as day 15 after Mobility Plus® supplementation. Result: Present study revealed that lameness, joint mobility, pain and weight-bearing scores significantly (p and lt; 0.001) decreased in dogs as early as day 15; hence, the overall clinical condition score also decreased significantly (p and lt; 0.001) as early as day 15 after Mobility Plus® supplementation. Supplementation of Mobility Plus® has antiarthritic and anti-inflammatory activities. Mobility Plus® could be recommended for the amelioration of joint inflammation and osteoarthritis conditions in canines.
In-vivo evaluation of different fungicides, plant extracts, bio-control agents and organics amendments for management of dry root rot of chickpea caused by Macrophomina phaseolina
Authors: Lakhran Lalita , Ahir R.R.
Published: August 2021

The present study was planned to evaluate the efficacy of various fungicides, plant extracts, biocontrol agents and oil cakes against Macrophomina phaseolina causing dry root rot of chickpea. Among the tested biocontrol agents against Macrophomina phaseolina, T. viride was found the most effective against the fungus followed by T. harzianum, Bacillus subtalis and P. fluorescens was the least effective in reducing root rot incidence. Among the fungicides carbendazim was found most effective and recorded minimum root rot incidence. Among plant extracts, garlic extract was found most effective in reducing root rot incidence followed by neem leaf extract. In the case of organic amendments, Neem cake was the most effective in reducing the root rot incidence while wool waste and goat manure was found least effective in controlling root rot incidence.
Centering Transgender Survivors' Experiences of Intimate Partner Violence Victimization: A Critique of Dominant Approaches to Research and Service Provision
Authors: Dolan C. V. , Conroy Nicole E.
Published: August 2021

Transgender (trans) survivors are infrequently included in the intimate partner violence (IPV) literature, and they are rarely the central subjects of IPV research. Similarly, trans survivors are rarely at the center of IPV service provision. In this article we articulate the importance of centering trans survivors in IPV research and practice through developing a nuanced understanding of the unique manifestations of abuse for trans individuals. Using intersectionality (Collins, 2019; Crenshaw, 1989, 1991) as our theoretical framework, we discuss the manifestations of dominance in trans IPV research and service provision. Specifically, we explain how cissexism, binarism, trans misogyny, and dysphoria reify White supremacist cisheteropatriarchy in intimate relationships, research, and service provision. We argue the importance of researchers and service providers alike to recognize and detect identity abuse tactics as well and how they contribute to the unique barriers trans survivors encounter to access resources and their help-seeking behaviors. With a more nuanced understanding of the ways that White supremacist cisheteropatriarchy affect trans individuals' experiences of IPV, researchers and service providers will be better able to understand and respond to abuse tactics used against trans people.
Linhas Orientadoras para Pensar, Desenvolver e Implementar a Comunicação em Saúde em Portugal
Authors: Miranda Débora , Galhordas Alves Isa , Salavisa Marta
Published: August 2021

A pandemia pelo vírus SARS-CoV-2 expôs e agravou muitas fragilidades dos sistemas de saúde, algumas já identificadas por organizações internacionais, nomeadamente as carências de meios materiais e humanos ou o insuficiente envolvimento da sociedade civil nos processos de decisão. À medida que as consequências socioeconómicas da pandemia se agravam e a fadiga pandémica se instala, outra fragilidade é posta a descoberto no espaço público e mediático: a falta de uma massa crítica de comunicação em saúde, com consequências diretas na gestão da pandemia. Comunicar neste contexto de crise e incerteza exige identificar os factos importantes a comunicar a diferentes segmentos da população, clarificar mitos e informações falsas, caracterizar as incertezas relevantes, ouvir e envolver os stakeholders e os cidadãos, desenvolver e testar as mensagens e monitorizar e avaliar as estratégias implementadas. A utilização da comunicação enquanto estratégia de apoio à gestão torna as organizações mais capazes de construir confiança, criar reputação, gerir relações com stakeholders internos e externos e de se prepararem para as incertezas do futuro, competências fundamentais para gerir uma crise sanitária. Dada a escassez de evidência científica sobre a comunicação em saúde realizada em Portugal, parte significativa da análise e diagnóstico é baseada no conhecimento empírico das autoras, adquirido através da experiência profissional, na área da comunicação, em diversas instituições de saúde. No final do artigo, as autoras propõem linhas orientadoras para pensar, desenvolver e implementar a comunicação em saúde em Portugal, nomeadamente numa crise sanitária, sustentadas numa cultura de liderança, colaboração e confiança.
Attempts to Access a Series of Pyrazoles Lead to New Hydrazones with Antifungal Potential Against Candida Species Including Azole-Resistant Strains
Authors: NEGRU Georgiana , KAMUS Laure , Bîcu Elena , Shova Sergiu , SENDID Boualem , DUBAR Faustine , GHINET Alina
Published: August 2021

The treatment of benzylidenemalononitriles 3a-c with phenylhydrazines 4a-n in refluxing ethanol did not provide pyrazole derivatives but furnished hydrazones 1a-o. The structure of hydrazones was secured by X-Ray analysis. Newly synthesized hydrazones 1a-o were tested against 8 Candida spp. strains in a dose response assay to determine the minimum inhibitory concentration (MIC99). Five compounds 1c, 1d, 1i, 1k and 1l were identified as promising antifungal agents against Candida spp. (C. albicans SC5314, C. glabrata, C. tropicalis, C. parapsilosis and C. glabrata (R azoles)) with MIC99 values ranging from 16 to 32 µg/mL. To further evaluate the antifungal potential of the active compounds, they have been assayed against a mammalian cell line HEK293 to determine general cell toxicity and on NCI-60 cancer cell lines panel, demonstrating selectivity antifungal activity over cytotoxicity.
Tipping Point Towards Biodiversity Conservation? Local and Global Consequences of the Application of ‘Rights of Nature’ by Ecuador
Authors: Guayasamin Juan M. , Vandegrift Roo , Policha Tobias , Encalada Andrea C. , Greene Natalia , Ríos-Touma Blanca , Endara Lorena , Cárdenas Rafael E. , Larreátegui Fred , Baquero Luis , Arcos Inty , Cueva José , Peck Mika , Alfonso-Cortes Felipe , Thomas Daniel , DeCoux José , Levy Elisa , Roy Bitty A.
Published: August 2021

In 2008, Ecuador recognized the Constitutional Rights of Nature in a global first. This recognition implies a major shift in the human-nature relationship, from one between a subject with agency (humans) and an exploitable object (Nature), to a more equilibrated relationship of respect. However, the lack of a standard legal framework has left room for subjective interpretations and variable implementation. The recent widespread concessioning of pristine ecosystems to mining industries in Ecuador has set up an unprecedented conflict and test of these rights. Currently, a landmark case involving Los Cedros Protected Forest and mining companies has reached the Constitutional Court of Ecuador. If Ecuador’s highest Court rules in favor of Los Cedros and the Rights of Nature, it would set a legal precedent with enormous impact on biological conservation in Ecuador and, potentially, the world. Such a policy shift offers a novel conservation strategy, through citizen oversight and action.
A Novel Heterogeneous Parallel Convolution Bi-LSTM for Speech Emotion Recognition
Authors: Zhang Huiyun , Huang Heming , Han Henry
Published: August 2021

Speech emotion recognition remains a heavy lifting in natural language processing. It has strict requirements to the effectiveness of feature extraction and that of acoustic model. With that in mind, a Heterogeneous Parallel Convolution Bi-LSTM model is proposed to address these challenges. It consists of two heterogeneous branches: the left one contains two dense layers and a Bi-LSTM layer, while the right one contains a dense layer, a convolution layer, and a Bi-LSTM layer. It can exploit the spatiotemporal information more effectively, and achieves 84.65%, 79.67%, and 56.50% unweighted average recall on the benchmark databases EMODB, CASIA, and SAVEE, respectively. Compared with the previous research results, the proposed model achieves better performance stably.
Prediction of Cardiorespiratory Fitness in Czech Adults: Normative Values and Association with Cardiometabolic Health
Authors: Maranhao Neto Geraldo A. , Pavlovska Iuliia , Polcrova Anna , Mechanick Jeffrey , Infante-Garcia Maria , Pantaleon José , Araujo Miguel , Nieto-Martinez Ramfis , Gonzalez-Rivas Juan P.
Published: August 2021

Cardiorespiratory fitness (CRF) is a strong independent predictor of morbidity and mortality. However, there is no recent information about the impact of CRF on cardiometabolic risk specifically in Central and Eastern Europe, which are characterized by different biological and social determinants of health. Normative CRF values were proposed and the association between CRF and cardiometabolic outcomes was evaluated in an adult Czechian population. In 2054 participants (54.6 % females, median 48 years), the CRF was predicted from a non-exercise equation. Multivariable-adjusted logistic regressions were carried out to determine the associations. Higher CRF quartiles were associated with lower prevalence of hypertension, type 2 diabetes (T2D) and dyslipidaemia. Comparing subjects within the lowest CRF, those within the highest CRF had decreased chances of hypertension (odds ratio [OR] = 0.36; 95% CI: 0.22-0.60); T2D (OR=0.16; 95% CI 0.05-0.47), low HDL-c (OR=0.32; 95% CI 0.17-0.60), high low-density lipoprotein (OR=0.33; 95% CI 0.21-0.53), high triglycerides (OR=0.13; 95 CI 0.07-0.81), and high cholesterol (OR=0.44; 95% CI 0.29-0.69). There was an inverse association between CRF and cardiometabolic outcomes, supporting the adoption of a non-exercise method to estimate CRF of the Czech population. Therefore, more accurate cardiometabolic studies can be performed incorporating the valuable CRF metric.
Missed Opportune Children for Immunisation versus Immunisation Defaulters: Why Are They Indistinguishable?
Authors: Idris Israel Oluwaseyidayo , Ayeni Gabriel Omoniyi
Published: August 2021

The two major global immunisation agenda framings (Missed Opportunity for Immunisation, MOI vs Immunisation Defaulting) are interchangeably and inappropriately used in public health research and practice with flawed or misleading strategies recommended and adopted in various settings globally. This is evident in the fact that many opportunities to adopt evidence/findings from immunisation coverage research in policy are grossly missed. Ineffectiveness of inappropriate interventions from biased evidence can discourage and mislead the governance to make radical decisions by discretion. This could be the reason for the inability of low-and middle-income countries to vaccinate 80% of their children and otherwise; this also poses a global health threat to capable nations. The current guideline and information on MOI and immunisation defaulting appear insufficient and a little clarification on it would assist forerunners in immunisation to achieve measurable progress in ensuring good coverage especially in low-and middle-income countries. Consequently, this paper is aimed at addressing this issue in immunisation practice with appropriate recommendations. Optimistically, this will stimulate further discussions, streamline differences, and gear global immunisation governance on the subject matter, to achieve the target coverage by 2030 in low-and middle-income countries.
Graph Coverings for Investigating Non Local Structures in Proteins, Music and Poems
Authors: Planat Michel , Aschheim Raymond , Amaral Marcelo , Fang Fang , Irwin Klee
Published: August 2021

It is shown how the secondary structure of proteins, musical forms and verses of poems are approximately ruled by universal laws relying on graph coverings. In this direction, one explores the group structure of a variant of the SARS-Cov-2 spike protein and the group structure of apolipoprotein-H, passing from the primary code with amino acids to the secondary structures organizing the foldings. Then one look at the musical forms employed in the classical and contemporary periods. Finally, one investigates in much detail the group structure of a small poem in prose by Charles Baudelaire and that of the Bateau Ivre by Arthur Rimbaud.
Energy Metabolism in Relation to Diet and Physical Activity: A South Asian Perspective
Authors: Wulan Siti Narsito , Raza Qaisar , Pramita Hera Sisca , Martati Erryana , Maligan Jaya Mahar , Mageshwari Uma , Fatima Itrat , Plasqui Guy
Published: August 2021

The prevalence of overweight and obesity is increasing worldwide not only in Western countries but also in Asian countries. Among Asian countries, South Asian countries experience the rapid increase of overweight and obesity that co-exist with the rapid increase of obesity-related non communicable diseases such as diabetes, dyslipidemia and cardiovascular. The phenomena in South Asian countries are triggered by growth in population size, population aging, urbanization and changes in lifestyle including increases in energy intake and reductions in physical activity. The imbalance between energy intake and energy expenditure leads to the development of positive energy balance, which over the time acumulate in a higher body fat. South Asians were reported to have a more unfavorable body composition with a higher body fat percentage as compared to BMI-matched Caucasians. The differences in body composition between South Asians and Caucasians contribute to differences in resting energy expenditure, in which South Asians have a lower resting energy expenditure as compared to BMI-matched Caucasians. Resting energy expenditure is the largest component of daily total energy expenditure, and therefore play an important role in determining the energy balance between energy intake and expenditure.
Welding of Copper to Aluminium With Laser Beam Wavelength of 515 nm
Authors: Mathivanan Karthik , Plapper Peter
Published: August 2021

In laser joining of copper (Cu) and aluminum (Al) sheets, the Al sheet is widely chosen as the top surface for laser irradiation because of increased absorption of laser beam and lower melting temperature of Al in contrast to Cu. This research focus on welding from Cu side to Al sheet. The main objective of irradiating the laser beam from the copper side (Cu on top) is to exploit higher solubility of Al in Cu. A significantly lower laser power can be used with 515 nm laser in comparison to 1030 nm. In addition to low laser power, a stable welding is obtained with 515 nm. Because of this advantage, 515 nm is selected for the current research. By fusion of Cu and Al the two sheet metals are welded, with presence of beneficial Cu solid solution phase and Al+Al2Cu in the joint with the brittle phases intermixed between the ductile phase. Therefore the mixed composition strengthens the joint. However excessive mixing leads to formation of more detrimental phases and less ductile phases. Therefore optimum mixing must be maintained. Energy dispersive X-ray spectroscopy (EDS) analysis indicate that large amount of beneficial Cu solid solution and Al rich phases is formed in the strong joint. From the tensile shear test for a strong joint, fracture is obtained on the heat-affected zone (HAZ) of Al. Therefore the key for welding from copper side is to have optimum melt with beneficial phases like Cu and Al+ Al2Cu and the detrimental phases intermixed between the ductile phases
From Information and Quantum Physics to Consciousness and Reality
Authors: Verheyen Peter
Published: August 2021

How does the world around us work and what is real? This question has preoccupied humanity since its beginnings. From the 16th century onwards, it has been periodically necessary to revise the prevailing worldview. But things became very strange at the beginning of the 20th century with the advent of relativity theory and quantum physics. The current focus is on the role of information, there being a debate about whether this is ontological or epistemological. A theory has recently been formulated in which spacetime and gravity emerges from microscopic quantum information, more specifically from quantum entanglement via entanglement entropy. A latest theory describes the emergence of reality itself through first-person perspective experiences and algorithmic information theory. In quantum physics, perception and observation play a central role. Perception, interaction with the environment, requires an exchange of information. Via biochemical projection, information is given an interpretation that is necessary to make life and consciousness possible. The world around us is not at all what it seems.
Enhancement of Antibiofilm Activity of Ciprofloxacin against Staphylococcus aureus by Administration of Antimicrobial Peptides
Authors: Yasir Muhammad , Dutta Debarun , Willcox Mark Duncan Perry
Published: August 2021

Staphylococcus aureus can develop resistance by mutation, tranfection or biofilm formation. Resistance was induced in S. aureus by growth in sub-inhibitory concentrations of ciprofloxacin for 30 days. The ability of the antimicrobials to disrupt biofilms was determined using crystal violet and live/dead staining. Effects on the cell membranes of biofilm cells was evaluated by measuring release of dyes and ATP and nucleic acids. S. aureus did not develop resistance to the AMPs but resistance increased to ciprofloxacin by 128 times after 30 passages. Only peptides reduced biofilms of ciprofloxacin resistant cells. The antibiofilm effect of melimine with ciprofloxacin was more (27%) than with melimine alone at 1X MIC (p < 0.001). Similarly, at 1X MIC the combination of Mel4 and ciprofloxacin produced more (48%) biofilm disruption than Mel4 alone (p < 0.001). Combinations of either of the peptides with ciprofloxacin at 2X MIC released  66 nM ATP, more than either peptide alone (p  0.005). At 2X MIC, only melimine in combination with ciprofloxacin released DNA/RNA which was 3 times more than released by melimine alone (p = 0.043). These results suggest the potential use of melimine and Mel4 with conventional antibiotics for the treatments of S. aureus biofilms.
An Amyloid Agnostic Reformulation of the Alzheimer’s Disease: The Long Gene Vulnerability Hypothesis
Authors: Soheili-Nezhad Sourena
Published: August 2021

Alzheimer’s disease (AD) is a genetically complex senile neurodegeneration with unknown etiology. The first gene discovered to be mutated in early-onset AD, the amyloid precursor protein (APP), has been widely assumed as a causal factor in the disease cascade due to its generation of Aβ species. APP has an evolutionarily conserved biological role and activates a signaling program with notable similarities to integrin—a cell adhesion receptor with a wide array of functions. Intriguingly, several AD genome-wide association study (GWAS) candidate genes, including the SHARPIN locus recently reported by us and others, influence signaling of the integrin pathway. Integrins are focal adhesion regulators and serve in nervous system development, synaptic plasticity, and Tau phosphorylation. These observations suggest that the function of APP probably goes beyond Aβ generation in AD. Aging—the strongest risk factor for AD—is associated with various clock-like events in cells. For instance, neurons are continuously impacted by stochastic ‘hits’ to their genomes in aging, in the forms of DNA damage, insertion-deletions, copy-number variations (CNVs) and other types of somatic mutations. DNA damage and somatic mutations can result in neoplastic changes and cancer in mitotically active cells. However, their consequences in post-mitotic cells such as aging neurons are less defined. The current hypothesis holds that the stochastic loss of DNA sequence data at random loci in aging affects longer genes by chance more frequently. As a result, the biological processes coordinated by long genes may be more vulnerable to such random aging effects. Curiously, as shown by us and others, long genes are strongly enriched for synapse- and cell adhesion-related ontologies, more than any other biological process or cellular compartment. In addition, among various cell types, neurons possess the highest levels of long gene expression and are therefore more vulnerable to such harmful effects. The long gene vulnerability hypothesis provides a simple link between aging and the genetic landscape of AD and warrants new strategies for disease modification.
Hyaluronan-Cholesterol Nanogels for the Enhancement of the Ocular Delivery of Therapeutics
Authors: Zoratto Nicole , Forcina Laura , Matassa Roberto , Mosca Luciana , Familiari Giuseppe , Musarò Antonio , Mattei Maurizio , Coviello Tommasina , Di Meo Chiara , Matricardi Pietro
Published: August 2021

The anatomy and physiology of the eye strongly limit the bioavailability of locally administered drugs. The entrapment of therapeutics into nanocarriers represents an effective strategy to topically treat some ocular disorders, as they may protect the entrapped molecules, facilitating drug residence on the ocular surface and/or its penetration into different ocular compartments. The present work shows the activity of hyaluronan-cholesterol nanogels (NHs) as ocular permeation enhancers. Thanks to their bioadhesive properties, NHs firmly interact with the superficial corneal epithelium, without penetrating the stroma, modifying the transcorneal penetration of loaded therapeutics. Ex-vivo transcorneal permeation experiments showed that the permeation of hydrophilic drugs (i.e. tobramycin and diclofenac sodium salt), loaded in NHs, is significantly enhanced when compared to the free drug solutions. On the other side the permeation of hydrophobic drugs (i.e. dexamethasone and piroxicam) is strongly dependent on the water solubility of the entrapped molecules. The obtained results suggest that NHs formulations can improve the ocular bioavailability of the instilled drugs by increasing their preocular retention time (hydrophobic drugs) or facilitating their permeation (hydrophilic drugs), thus opening the route for the application of HA-based NHs in the treatment of both anterior and posterior eye segment diseases.
Considerations and inquiries about the dynamics of the brazilian state facing the demands of schooling
Authors: Lemes Sebastião de Souza
Published: August 2021

The aim of this study is to understand issues of public policy, government and governance in relation to Education in Brazil, making use, for this analysis, of an understanding of evaluative and managerial instruments, in addition to public policies aimed at school education, to understand the scenario built in national education. Under the guise of cognitive analysis of public policies and their foundations, the state of the art is mobilized to better understand and analyze the guiding concepts of this work, which also considers theories about a change in the bias of bureaucracy and its role in the state. In the end, it is noted that the actions of the Brazilian government, in line with international pressure and evaluation mechanisms, assume an interventionist and inefficient character, which places the equitable democratization of education, advocated in the 1988 Constitution, as a challenge yet to be reached and with many obstacles along the way.
KEBIJAKAN SISTEM APLIKASI PELAYANAN KEPEGAWAIAN ON-LINE UNTUK MEWUJUDKANE-GOVERNMENT DI PEMERINTAH KABUPATEN KARANGANYAR (STUDI KASUS DI PEMERINTAH KABUPATEN KARANGANYAR)
Authors: , Haryono , , Isharyanto , Firdaus Sunny Ummul
Published: August 2021

Abstrak
Tujuan dari penulisan ini adalah untuk mengetahui kebijakan Sistem Aplikasi Pelayanan Kepegawaian On  Line (SAPK On Line) untuk mewujudkan E-Government di Pemerintah Kabupaten Karanganyar studi kasus di Pemerintah Kabupaten Karanganyar. Metode penelitian yang digunakan adalah metode penelitian kualitatif jenis penelitian empiris. Kebijakan SAPK On Line di Badan Kepegawaian dan Pemberdayaan Sumber Daya Manusia (BKPSDM) Kabupaten Karanganyar belum sepenuhnya dilaksanakan karena input  data  Pegawai  Negeri  Sipil  masih  menggunakan  Sistem  Informasi  Manajemen  Kepegawaian (SIMPEG) yang bersifat   dengan format   yang tidak dapat dikonversi ke dalam format SAPK On Line. Sehingga database PNS yang masuk tidak sinkron antara SAPK On Line dengan SIMPEG apabila ada PNS yang mengajukan kenaikan pangkat dan kenaikan gaji. Terutama dalam hal kenaikan pangkat, ketidak sinkronan database PNS tersebut berakibat tertundanya proses kenaikan pangkatnya. Hal inilah yang menghambat terwujudnya E-Government yang ideal di lingkungan Pemerintah Kabupaten kertas, sedang tujuan dari SAPK On Line yaitu paper less atau mengurangi jumlah kertas dalam setiap pelayanan kepegawaian.

Kata Kunci : SAPK On Line, E-Government, Kabupaten Karanganyar
HAMBATAN KURATOR DALAM MENYELESAIKAN PIUTANG KOPERASI YANG DIPUTUS PAILIT
Authors: Afreeportamara Nindita Widi , Pujiyono ,
Published: August 2021

Abstract
This article discusses the challenges posed by curators in handling bankrupt assets and their  solutions. This study uses normative or doctrinal legal research methods that act prescriptively or applied. This study uses sources of primary and secondary legal materials. The analysis technique  used is the syllogism method that uses deductive thinking patterns. Based on the results of this  study it can be concluded. Curators when settling receivables of cooperatives that are decided bankrupt experience obstacles, namely in terms of regulations in the form of a lack of legal protection for curators and collisions between Law Number 37 of 2004 concerning bankruptcy and postponement of debt repayment obligations  Article 9 and Article 16. The Cooperative Management still recognizes cooperative assets and the existence of irresponsible Managers. In the case of the amount of money spent for the Cooperative in a state of loss and unable to pay its debts. Curators have difficulty determining Creditors and there are Fictitious Creditors, the last to approve the funds because they ask the Cooperative that is terminated requires not small amounts of funds
Keywords: obstacle; bankruptcy; cooperative; curators

Abstrak
Artikel ini bertujuan untuk mengetahui hambatan-hambatan yang dihadapi oleh kurator dalam  mengurus harta pailit beserta solusinya. Penelitian ini menggunakan metode penelitian hukum normatif atau doktrinal yang bersifat preskriptif atau terapan. Penelitian ini menggunakan sumber bahan hukum primer dan sekunder. Teknik analisis yang digunakan yaitu dengan metode silogisme yang menggunakan pola berpikir deduktif. Berdasarkan hasil penelitian ini dapat disimpulkan. Kurator saat menyelesaikan piutang koperasi yang diputus pailit mengalami hambatan-hambatan yaitu dalam hal regulasi berupa kurangnya perlindungan hukum terhadap kurator dan benturan antara Pasal 9 dan Pasal 16 Undang-undang Nomor 37 Tahun 2004 tentang kepailitan dan penundaan kewajiban pembayaran utang. Pengurus Koperasi masih menguasai harta koperasi dan adanya Pengurus yang tidak bertanggung jawab. Dalam hal Jumlah harta yaitu apabila Koperasi dalam keadaan merugi dan tidak dapat membayar utang-utangnya. Kurator kesulitan menentukan Kreditor dan terdapat Kreditur Fiktif ,yang terakhir Ketersediaan dana karena penyelesaian suatu Koperasi yang diputus membutuhkan dana yang tidak sedikit.
Kata kunci: hambatan; kepailitan; koperasi; kurator
PERTANGGUNGJAWABAN PELAKU MONEY LAUNDERING MELALUI BINANCE COIN
Authors: Pramudiya Kt Firnanda
Published: August 2021

The results of this research in this article show that the existence of virtual money in trade as a means of investment and payment in Indonesia can be said to be illegal when viewed from Law Number 7 of 2011 concerning Currencies. Digital money users in Indonesia are widely used in terms of business, which if traced in Indonesia there are already digital money such as Bitcoin and Binance Coin and others. Then, there is also the responsibility of perpetrators of money laundering crimes who use digital money as an investment tool that has a negative impact on the State of Indonesia, especially those related to this business because the person or group who committed the crime uses technological advances with dirty goals so that the perpetrator can be caught law using Law No. 8 of 2010 concerning The Prevention and Eradication of Money Laundering.

Keywords: Money laundering, digital currency, criminal liability

 

Hasil penelitian dalam artikel ini menunjukkan eksistensi uang virtual dalam perdagangan sebagai alat investasi dan pembayaran di Indonesia dapat dikatakan tidak sah penggunaannya jika dilihat dari Undang-undang Nomor 7 Tahun 2011 Tentang Mata Uang. Pengguna uang digital di Indonesia banyak dipakai dalam hal bisnis, yang jika ditelusuri di Indonesia sudah ada uang digital seperti Bitcoin dan Binance Coin dan lain-lain. lalu, ada pun tanggung jawab pelaku tindak pidana pencucian uang yang memakai uang digital sebagai sarana alat investasi berdampak negative bagi Negara Indonesia, terutama yang menyangkut terkait bisnis ini disebabkan orang atau kelompok yang melakukukan kejahatan tersebut menggunakan kemajuan teknologi dengan tujuan yang kotor sehingga pelaku bisa di hukum menggunakan Undang-undang No. 8 Tahun 2010 tentang pencegahan dan pemberantasan tindak pidana pencucian uang.

Kata Kunci: Pencucian uang, mata uang digital , pertanggung jawaban pidana
KONSEP PERLINDUNGAN HUKUM BAGI TENAGA MEDIS DALAM PENANGANAN COVID 19
Authors: Handini Dyah Tri
Published: August 2021

This article aims to understand the concept of legal protection for medical personnel in handling COVID-19. The increase in the incidence of covid 19 has an impact on the workload experienced by medical personnel, causing a decrease in the immune system of medical personnel. Most people who think that covid 19 is just a conspiracy have an impact on reducing public awareness in preventing covid 19. People who lack awareness of the importance of the covid 19 protocol will result in medical personnel being more at risk of being exposed to and experiencing covid 19. The results of this article show that there has been legal protection for medical personnel in handling COVID-19, both criminal law protection and employment law. The conclusion of this article is that the aspect of legal protection for medical personnel is contained in the codeki, Law R1 NO 29 of 2004 concerning Medical Practice, especially Article 48 concerning Medical Secrets, Regulations of the Minister of Health of the Republic of Indonesia number 269 and 290 and the Ministry of Health of the Republic of Indonesia.

Keywords: Legal Protection, Medical Personnel, Covid-19.

 

Artikel ini bertujuan untuk megetahui konsep perlindungan hukum bagi tenaga medis dalam penanganan covdi 19. Peningkatan kejadian covid 19 berdampak pada beban kerja yang dialami oleh tenaga medis sehingga meyebabkan penurunan sistem imun pada tenaga medis. Kebanyakan masyarakat yang menganggap bahwa covid 19 hanyalah sebuah konspirasi berdampak pada berkurangnya kesadaran masyarakat dalam pencegahan covid 19. Masyarakat yang kurang kesadaran akan pentingnya protokol covid 19 akan mengakibatkan tenaga medis lebih berisiko terpapar dan mengalami covid 19. Hasil artikel ini menunjukkan bahwa telah adanya perlidungan hukum bagi tenaga medis dalam penanganan covid 19, baik perlindungan hukum pidana maupun hukum ketenagakerjaan.  Kesimpulan artikel ini bahwa aspek perlindungan hukum bagi tenaga medis tertuang pada kodeki, UU R1 NO 29 Tahun 2004 tentang Praktek Kedokteran, khususnya pasal 48 tentang Rahasia Kedokteran, Peraturan Menteri Kesehatan Republik Indonesia nomor 269 dan 290 serta Kemenkes RI.
Kata Kunci: Perlindungan Hukum, Tenaga Medis, Covid-19
HUKUM DAN HAK PASIEN DALAM MENDAPATKAN PELAYANAN KESEHATAN DI ERA PANDEMIK
Authors: UTORO DWI
Published: August 2021

The whole world community agrees that the right to health is a basic right (Fundamental Right) that is owned by every human being. The right to health which was previously seen as merely a private matter related to the fate or gift of God, has now undergone a very large paradigm shift into a legal right (legal rights) which is certainly guaranteed by the state. In the midst of the Covid-19 pandemic that has spread to almost all regions of Indonesia, the Government must be prepared to issue various strategic policies so that it can carry out its obligations to always guarantee the fulfillment of the right to health for all people. This research uses the method of library research with the statutory approach. This research found that the Government's policy to determine the Public Health Emergency status and choosing Large-Scale Social Restrictions as an option to respond to Public Health Emergency is a wise step, besides the Government must also pay attention to the economic and fiscal sectors according to the conditions and capabilities of the country.

Keywords: Right to health, health service, Pandemic Covid-19.

 

Di tengah pandemi Covid-19 yang telah menyebar hampir ke seluruh wilayah Indonesia, Pemerintah harus sigap mengeluarkan berbagai kebijakan strategis agar dapat menjalankan kewajibannya untuk senantiasa menjamin terpenuhinya hak atas kesehatan bagi seluruh masyarakat. Penelitian ini menggunakan metode penelitian kepustakaan dengan pendekatan peraturan perundang-undangan. Penelitian ini menemukan bahwa Pemerintah terlalu lamban mengambil tindakan antisipatif maupun mitigasi dalam menanggulangi pandemi corona. Pada akhirnya Pemerintah menetapkan status Darurat Kesehatan Masyarakat dan memilih Pembatasan Sosial Berskala Besar sebagai opsi untuk merespons Kedaruratan Kesehatan Masyarakat, disamping Pemerintah juga tetap harus memperhatikan sektor ekonomi dan fiskal sesuai kondisi dan kemampuan negara.

Kata Kunci: Hak Pasien, Pelayanan Kesehatan, Pandemi Covid-19.
Hybrid Strategy for Routing, Modulation and Spectrum Assignment in Elastic Optical Networks
Authors: Assis Karcius , Santos Alex , Almeida Raul , Moura Thiale , Vieira Rafael , Mesquita Leonardo , Correia Felipe , Pereira Helder
Published: August 2021

In this paper, we propose a novel hybrid strategy that combines mixed integer linearprogramming (MILP) formulation with different alternative routing approaches that is capable ofsolving, simultaneously, the routing, modulation format and spectrum assignment problem in thedesign of elastic optical networks. We extend our proposal to a path-link formulation that, althoughit is not guaranteed to find the optimal solution, it has shown reasonable solutions within inferiorsimulation time, allowing it to be used in not very short networks. We also compare our proposalwith another MILP formulation and three adapted heuristics, all available in the literature. Theresults show the benefits of our proposal considering diverse simulation scenarios and differentnumber of modulation formats over19realistic networks in terms of simulation run time andmaximum number of used set of slots.
Environmentally Sound Alternative Cropping Systems For Rice-Wheat Systems In North West India
Authors: Tripathi SC , Venkatesh Karnam , Meena Raj Pal
Published: August 2021

Continuous cultivation of Rice-Wheat Cropping System (RWCS) in Indo-Gangetic Plains of India is showing declining factor productivity coupled with many environmental problems. Diversifying the RWCS is one of the environmental friendly options for sustaining food production.Four crop rotations involving maize and sorghum in summer, wheat/ potato/ mustard in winter followed by short duration green gram in late spring were studied to identify the most productive and economic combination from 2017 to 2020. Ranking of treatments by Tukey’s test of significance indicated that the maize-potato-wheat (16.49 t ha-1) combination was best in terms of system productivity calculated in terms of wheat equivalent yield (WEY). Maize-wheat-green gram crop sequence was most profitable by having higher Land Use Efficiency (LUE=87.67%) and net return (NR=1577.1 $ha-1). The gross margin comparison revealed that maize-based crop sequences earned higher gross returns (23.17%), net return (93.66%), and B: C ratio (23.7%) than sorghum-based crop sequences. Soil health parameters were improved under the maize-mustard-green gram system, which increased the organic carbon content by 28.65% and available N by 34.91%. Adoption of alternate cropping sequences instead of rice-wheat, in the Indo-Gangetic Plains of India could be more sustainable, profitable, and environment friendly.
Strategy for Rapid Recovery of Simultaneous Sulfide and Nitrite Removal under High Substrate Inhibition
Authors: Wang Kaiquan , Qaisar Mahmood , Chen Bilong , Liu Siyi , Wu Yuanyuan , Zheng Ziling , Cai Jing
Published: August 2021

The paper deals with the strategy for a quick recovery of reactor treating sulfide and nitrite simultaneously under inhibition caused by high substrate concentration. For influent sulfide concentration of 360 mg S/L, respective sulfide and nitrite removal percentages dropped to 74.19% and 14.33% due to inhibition caused by high sulfide and nitrite concentrations. It was found that reduction in the influent substrate concentration (300 mg S/L) could not revive the nitrite removal performance in 4 days’ operation, which still showed a declining tendency from 47.16–18.52%. Regulating the influent pH around 6.70 ± 0.10, it only took 4 days to recover the performance for 300 mg S/L. Furthermore, at influent sulfide concentration increased to 360 mg S/L, respective sulfide and nitrite removal percentages were 99.76 ± 0.27% and 100%. The strategy of regulating influent pH could recover the process performance in a short term, which would provide great convenience for subsequent process research.
Genetic Fine-Mapping With Dense Linkage Disequilibrium Blocks
Authors: Mo Chen , Ye Zhenyao , Hatch Kathryn , Zhang Yuan , Wu Qiong , Liu Song , Lu Qing , Mitchell Braxton , Hong L. Elliot , Kochunov Peter , Ma Tianzhou , Chen Shuo
Published: August 2021

Background: Fine-mapping is an analytical step for causal prioritization of the polymorphic variants in a trait-associated genomic region observed in genome-wide association studies (GWAS). Prioritization of causal variants can be challenging due to linkage disequilibrium (LD) patterns among hundreds to thousands of polymorphisms associated with a trait. Hence, we propose an ℓ0 graph norm shrinkage algorithm to disentangle LD patterns by dense LD blocks consisting of highly correlated single nucleotide polymorphisms (SNPs). We further incorporate the dense LD structure for fine-mapping. Based on graph theory, the concept of "dense" refers to a condition where a block is composed mainly of highly correlated SNPs. We demonstrated the application of our new fine-mapping method using a large UK Biobank (UKBB) sample related to nicotine addiction. We also evaluated and compared its performance with existing fine-mapping algorithms using simulations.Results: Our results suggested that polymorphic variances in both neighboring and distant variants can be consolidated into dense blocks of highly correlated loci. Dense-LD outperformed comparable fine-mapping methods with increased sensitivity and reduced false-positive error rate for causal variant selection. Applying to a UKBB sample, this method replicated the loci reported in previous findings and suggested a strong association with nicotine addiction.Conclusion: We found that the dense LD block structure can guide fine-mapping and accurately determine a parsimonious set of potential causal variants. Our approach is computationally efficient and allows fine-mapping of thousands of polymorphisms.
Optimization of Lipase Catalyzed Biofuel Synthesis From Waste Filter Coffee Using Response Surface Methodology
Authors: KUTLUK TOGAYHAN
Published: August 2021

This study was executed that optimize an environmentally friendly lipase (Resinase® HT with the activity of 135,56 U/ml) catalyzed transesterification process from novel feedstock waste filter coffee oil for biofuel production. Response surface methodology (RSM) with the central composite design was performed to investigate the effect of experimental factors (enzyme content, oil/methanol molar ratio, reaction temperature) on the fatty acid methyl ester (FAME) conversion and also investigated to resolve the optimum design points. After the experimental studies the lowest FAME conversion was found as 71% when the enzyme content was 15%(%gr w/w), oil/methanol molar ratio was 0.17 and the reaction temperature value was 45 °C. According to the design response, 70.83% was observed in the same conditions. The highest FAME conversion of 97% was found when the enzyme content was 5%(%gr w/w), oil/methanol molar ratio was 0.25 and the reaction temperature value was 35 °C. The experimental run gave the FAME conversion of 96.80% at the same reaction conditions. The model fitted with the experimental values with R2 = 0.98. Also, classical soxhlet extraction and Dyer method oil yields were compared. 24 % and 20 % oil removed from waste coffee grounds in traditional soxhlet and Dyer method respectively. The extraction process took 30 minutes with the soxhlet method and 45 minutes with the Dyer method. The results are promising for the application of lipase catalyst for environmentally friendly and sustainable biodiesel production from waste coffee oils all over the world.