bluuebunny/crossref_metadata_2025 huggingface dataset:
Quasi-variational structure approach to systems with degenerate diffusions
Authors: Ito Akio
Published: July 2022

We consider the following system consisting of one strongly nonlinear partial differential inclusion, one linear PDE, and one ODE, which describes a tumor invasion phenomenon with a haptotaxis effect and was originally proposed by Chaplain and Anderson in 2003:

\begin{equation*} \begin{cases} u_t-\nabla \cdot (d_u (v) \nabla \beta (v{};u)-u \nabla \lambda (v))+\beta (v{};u) \ni 0,\\ v_t=-avw,\\ w_t=d_w \Delta w -bw+cu. \end{cases} \end{equation*}

This system has two interesting characteristics. One is that the diffusion coefficient

d_u

for the unknown function

u

in the partial differential inclusion depends on the function

v

, which is also unknown in this system. The other one is that the diffusion flux

\nabla \beta (v{};u)

of

u

also depends on

v

. Moreover, we are especially interested in the case that

\beta (v{};u)

is nonsmooth and degenerate under suitable assumptions. These facts make it difficult for us to treat this system mathematically. In order to overcome these mathematical difficulties, we apply the theory of evolution inclusions on the real Hilbert space

V^*

, the dual space of

V

, with a quasi-variational structure for the inner products, which was established by the author in 2019, and show the existence of time global solutions to the initial-boundary value problem for this system.
40 Years of Pfs48/45 Research as a Transmission-Blocking Vaccine Target of Plasmodium falciparum Malaria
Authors: Sauerwein Robert W. , Plieskatt Jordan , Theisen Michael
Published: July 2022

In the early 1980s, Richard Carter was among the first researchers to identify the sexual stage-specific Pfs48/45 protein, leading to the identification of target epitopes. Carter predicted its tertiary conformation while involved in a number of studies on naturally acquired sexual stage-specific antibodies. Pfs48/45 is a cysteine-rich surface protein of sexual stages of Plasmodium falciparum that plays a critical role in male gamete fertility. Antibodies against Pfs48/45 prevent parasite development in the mosquito vector, and therefore prevent the spread of malaria in the population. Since the gene was sequenced in the early 1990s, Pfs48/45 has been considered a prime target candidate for a malaria transmission-blocking vaccine. However, major manufacturing challenges—in particular, difficulty realizing satisfactory yields of a properly folded protein for the induction of functional antibodies—delayed clinical development significantly. These challenges were met roughly 20 years later. The first clinical trial with a Pfs48/45 subunit vaccine (R0.6C) was started in the Netherlands in early 2021. The excellent contributions to the long and winding path of Pfs48/45 research by Richard Carter are well recognized and are an integrated part of his seminal contributions to unraveling Plasmodium sexual stage biology.
The Virtues and Vices of Pfs230: From Vaccine Concept to Vaccine Candidate
Authors: Duffy Patrick E.
Published: July 2022

Among the Plasmodium falciparum surface antigens reported by Richard Carter and his colleagues decades ago, Pfs230 is currently the target of the most advanced candidate for a malaria transmission-blocking vaccine. First identified by its orthologue in the avian malaria parasite Plasmodium gallinaceum, the large cysteine-rich 14-domain Pfs230 antigen is displayed on the surface of gametes that emerge in the mosquito midgut. Gametes lacking Pfs230 cannot bind to red blood cells nor develop further into oocysts. Human antibodies against Pfs230 lyse gametes in the presence of complement, which largely explains serum transmission-blocking activity in Pfs230 antisera. A protein–protein conjugate vaccine that incorporates the first domain of the Pfs230 antigen induced greater serum transmission-reducing activity versus a similarly manufactured Pfs25 vaccine in U.S. trials, and is currently in phase II field trials in Mali.
Cattle-related trauma: a 10-year retrospective cohort study of patients admitted to a single tertiary trauma centre in Switzerland
Authors: Ehrhard Simone , Botte Federica , Klukowska-Rötzler Jolanta , Exadaktylos Aristomenis K. , Jakob Dominik A.
Published: July 2022

AIMS OF THE STUDY: Switzerland is traditionally an agricultural country with more than 50,000 farms and 1.5 million registered cows. However, contemporary literature on cattle-related trauma in Switzerland remain limited. The purpose of this study was to examine injury patterns and outcomes of patients who presented to a tertiary trauma centre in Switzerland following cattle-related trauma.
METHODS: Retrospective single-centre study over a 10-year period (2012–2021) including all patients experiencing cattle-related trauma. From retrieved charts demographics, injury data, and outcomes were collected and subsequently analysed.
RESULTS: A total of 94 patients with cattle-related injuries were identified. The median age was 52 years (interquartile range [IQR] 37–63) and 75% were male. Cattle-related injuries were most frequent among farmers (73%) and were most often caused by cows (86%), followed by bulls (10%). Blunt trauma (89%) was the leading mechanism of injury including headbutt (36%), kick (35%), physical contact (20%) and trampling injury (12%). Penetrating injury occurred in 11%, all caused by headbutt. Contusions (82%) and lacerations (45%) were the leading injuries, followed by face fractures (28%), closed head trauma (19%) and chest injuries (17%). Overall, 10% of all patients had a head abbreviated injury scale (AIS) score of ≥3 and 8% had a chest AIS of ≥3. The hospital admission rate was 49% for cow-related injury vs 90% for bull-related injuries, p = 0.023. Overall, in-hospital mortality was 3% and the median length of stay was 4.5 days (IQR 3–8) among patients admitted to the hospital.
CONCLUSIONS: Cattle-related injuries in Switzerland mainly affect farmers and are associated with considerable morbidity, especially when caused by bulls. Facial fractures, head injuries and chest injuries are common, and the latter two in particular can be severe. The results of the present study can be used for the implementation of data-driven prevention measures for the safe handling of cattle in Switzerland.
Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based study in Basel-Stadt and Basel-Landschaft
Authors: Jeong Ayoung , Galliker Fiona , Imboden Medea , Keidel Dirk , De Hoogh Kees , Vienneau Danielle , Siegrist Michael , Crivelli Luca , Lovison Gianfranco , Probst-Hensch Nicole
Published: July 2022

BACKGROUND: Subjective well-being is an important target in the COVID-19 pandemic. Residential greenness may help cope with stress and hence influence subjective well-being during this mentally and physically challenging time.
METHODS: We analysed the association between residential greenness and life satisfaction in 9,444 adults in the COVCO-Basel cohort. We assessed if the association is modified by age, sex, household income, financial worries, canton of residence, or month of study entry. In addition, we assessed if the association is attributed to specific types of greenspace or accessibility to greenspace.
RESULTS: The association between residential greenness and life satisfaction varied by age groups, household income, and financial worries. Residential greenness was positively associated with life satisfaction in those with high household income and the least financially worried, and negatively associated with life satisfaction in the youngest age group (18–29 years) and the most financially worried. Living closer to a forest, but not to a park or an agricultural area, was associated with lower life satisfaction in the youngest age group.
CONCLUSIONS: Residential greenness effects on life satisfaction vary according to sociodemographic characteristics. Living in a greener area does not benefit all dwellers in Basel and its region equally, with the most apparent benefit for those with high household income and without financial concerns.
Basque nationalists in Navarre: a long road to success
Authors: Krivushin I. V.
Published: July 2022

The aim of the article is to examine the reasons for the Basque nationalists’ improving electoral performance in Navarre in the late 2000–2010s. The author identifies the main stages of the historical development of Basque nationalism in Navarre and its confrontation with various forms of local regionalism (Fuerism, Carlism, and Navarrism) from the beginning of the 20th century up to the present, as well as the features of its evolution in comparison with the evolution of nationalism in other Basque territories. The analysis of electoral statistics and opinion polls shows that, in the post-Franco period, the traditional centrist and Catholic version of Basque nationalism, represented by the Basque Nationalist Party, was pushed back by its left and secular version (“Herri Batasuna”, “Batzarre”, “Aralar”, etc.) and that, in the last decade, Basque nationalists managed to significantly expand their influence among social groups that do not favour separatist claims and do not share nationalist feelings. On the one hand, the success of this expansion was due to the new electoral tactics of the Basque nationalists (formation of two coalitions – left and center-left), and, on the other, to the growing discontent of voters towards the central and regional authorities in the context of the financial crisis of 2008 – 2014 and the gradual increase in the popularity of the Basque language and strengthening of the Basque identity in Navarre. The rising separatist movement in Navarre, together with the growing popularity of secessionism in Galicia, threatens to increase the number of separatist-leaning regions in Spain and poses a serious challenge to the Spanish “State of Autonomous Communities.”
FATORES MOTIVACIONAIS PARA A PRÁTICA DE CORRIDA DE RUA
Authors: Cardoso Batista Maria Geovania , Antunes dos Santos Maria Gabriela , De Paula Nagem Marcelo , Lopes de Sales José Roberto , Ramos Veloso Silva Rosângela , Mendes Amaral Giovanna , Veloso Rocha Marinho Hellen
Published: July 2022

O presente estudo objetivou verificar os fatores motivacionais para a prática da corrida de rua. Trata-se de um estudo transversal, descritivo. A amostra foi composta por 90 praticantes de corrida de rua com idade média de 41,12 ± 12,12 anos, sendo 28 do sexo masculino e 62 do sexo feminino. Os voluntários responderam a um formulário estruturado que continham questões relacionadas aos objetivos do  estudo. Análise descritiva foi utilizada para caracterizar a amostra. As variáveis categóricas foram apresentadas na forma de frequência absoluta e frequência relativa. Foi evidenciado que do total de 161 respostas, 36.35% corresponderam à outros objetivos, onde a maioria destacou a promoção de saúde, 30,43% à condicionamento físico e 20,50% emagrecimento. Outros objetivos reportados incluiram competição (4,97%), aumento da força muscular (3,11%), hipertrofia muscular (2,48%) e definição muscular (1,86%). Considerando a totalidade das respostas,  132 (81,99%) refere-se à  percepção de  melhora completa por parte dos voluntários, de acordo com as suas respectivas motivações. Os principais fatores motivacionais para a prática da corrida de rua relatados pelos praticantes de corrida de rua foram promoção de saúde, condicionamento físico e emagrecimento.
Palavras-chave: Corrida. Motivação. Atividade motora.
Pendidikan Agama Kristen sebagai Sebuah Usaha Menumbuhkan Sikap Toleransi
Authors: Legi Hendrik , Keriapy Frets
Published: July 2022

Today, the rate of intolerance cases in Indonesia tends to increase. Even some cases that occur are carried out by children at school. Cases of increasing intolerance are our collective duty, in which there are parents as the first teachers of every children in the family, religious and government leaders in the social community, and teachers in this case, not only Civic Education teachers, but Christian Education teachers are obliged to take part in overcoming this problem. Christian Education teachers have succeeded in shaping the spiritual side of students, but in truth that is not enough. The success of the teacher is to be able to form spiritual, emotional, and social attitudes and to change behavior of the students. To see this, in this research, the author will use a qualitative method of description by using a literature study. This is done by the author, in order to see theoretically that Christian education must touch the realm of the public sphere to overcome this problwm.  The finding obtained from this research are that it is found that Christian Religius Education must be an education that seeks tolerance in religious behavior. It starts with changing heart. Therefore, it is important for Christian Education to participate in overcoming this problem in the public sphere.AbstrakDewasa ini, tingkat kasus intoleransi di Indonesia cenderung meningkat. Bahkan beberapa kasus yang terjadi dilakukan oleh anak sekolah. Kasus intoleransi yang meningkat menjadi tugas kita bersama, yang di dalamnya ada orang tua sebagai guru pertama dari setiap naradidi di dalam keluarga, tokoh-tokoh agama dan pemerintah di lingkungan masyarakat, dan guru di lingkungan sekolah. Guru dalam hal ini, bukan hanya guru Pendidikan Kewarganegaraan, melainkan guru pendidikan Kristiani wajib untuk ambil bagian dalam mengatasi persoalan ini. Guru pendidikan Kristiani berhasil membentuk sisi rohani naradidik, namun sejatinya, itu pun belum cukup. Keberhasilan guru adalah dapat membentuk sikap rohani, emosi, sosial dan sampai pada perubahan tingkah laku. Untuk melihat hal tersebut, maka dalam penelitian ini, penulis akan menggunakan metode kualitatif deskripsi dengan menggunakan studi pustaka. Hal ini dilakukan oleh penulis, supaya dapat melihat secara teori bahwa, pendidikan Kristiani harus menyentuh ranah ruang publik untuk mengatasi persoalan ini. Hasil yang peroleh dari penelitian ini, adalah ditemukan bahwa Pendidikan Agama Kristen harus menjadi Pendidikan yang mengupayakan toleransi dalam perilaku beragama. Hal ini dimulai dari mengubah hati. Oleh karena itu, pentingnya pendidikan Kristiani untuk masuk berpartisapasi dalam mengatasi persoalan ini di dalam ruang publik.
The role of interleukin 1 in the development of human diseases: focus on Anakinra (IL-1 receptor antagonist)
Authors: Nasonov E. L. , Samsonov M. Yu.
Published: July 2022

According to modern concepts, human immune-mediated inflammatory diseases (IMIDs), depending on the prevailing mechanisms of immunopathogenesis, are divided into two main categories – autoimmune and autoinflammatory.

At the same time, both autoimmune and autoinflammatory mechanisms are involved in the pathogenesis of most IMIDs, the complex interaction of which is reflected in the polymorphism of clinical manifestations, course variants, outcomes, and therapy efficacy. It is assumed that hyperproduction of cytokines of the interleukin (IL) 1 family, which is one of the key regulators of innate immunity, determines the “crossover” between the mechanisms of autoinflammation and autoimmunity in IMIDs. Anakinra is currently used in clinical practice to suppress the pathological effects of IL-1. An analysis of the results of the clinical use of Anakinra indicates that treatment with this drug should be considered as a promising direction in the pharmacotherapy of systemic autoinflammatory diseases (SAIDs) and critical conditions in children and adults associated with the development of hyperinflammation. The main directions of the Anakinra clinical research program are presented, including: determining the place of the drug in the implementation of the "Treat to Target" strategy and personalization of therapy, primarily in patients with “resistant” (difficult-to-treat) subtype of rheumatoid arthritis and comorbid pathology, as well as with severe forms of microcrystalline arthritis; the possibility of using Anakinra to improve the early diagnosis of SAIDs in children and adults; creation of the Russian register of patients with SAIDs, who are potentially indicated for treatment with Anakinra.
Are the goals of therapy achievable in patients with rheumatoid arthritis receiving upadacitinib in real clinical practice?
Authors: Amirjanova V. N. , Karateev A. E. , Pogozheva E. Yu. , Filatova E. S. , Samigullina R. R. , Mazurov V. I. , Anoshenkova O. N. , Lapkina N. A. , Baranov A. A. , Grineva T. Yu. , Lila A. M. , Nasonov E. L.
Published: July 2022

The aim of the study was to evaluate the effectiveness of UPA in RA patients in real clinical practice after 3 and 6 months of therapy.

Material and methods. The study included 63 RA patients with high activity of the disease. Activity was assessed according to the DAS28 (ESR), DAS28 (CR P), SDAI, CDAI; functional ability to HAQ; quality of life to the EQ-5D; disease activity according to the patient’s RAPID-3 index; the level of depression and anxiety to the HADS scale. The effectiveness of therapy was evaluated after 3 (n=45) and 6 (n=31) months of UPA therapy.

Results. Remission or low activity of the disease by 3 months of therapy was achieved by most patients: remission of 69.8% of patients, low activity of the disease – 16.3% of patients. Moderate or high activity persisted in 13.9% of patients. By the 6th month of UPA therapy, the number of remissions reached 90% , low activity – 3.3%, moderate activity persisted in 6.7% of patients, high activity of the disease was not in any patient. 20% improvement in function was achieved in 71.8% of patients by the 3rd month of therapy and in 77.8% – by the 6th month of treatment; the difference in average HAQ values by the 3rd month of therapy was 0.38 points, by the 6th month – 0.58 points. After 3 months of follow-up, 31.1% of patients continued taking GC, by 6 months – 24.2%. The dose of GC was reduced from an average of 7.23 mg/d to 5.6 mg/d. The percentage of patients requiring NSAIDs decreased from 95.2% to 35.6% and 33.3%, respectively. DMARDs continued to be received by 75.6% of patients by 3 months and 69.7% by 6 months of follow-up.

Conclusion. Achieving remission or low activity of the disease in patients with RA receiving UPA in real clinical practice is possible in most patients. A rapid decrease in inflammatory activity is accompanied by a significant improvement in the functional state and quality of life of patients. UPA therapy reduces the need for the use of NSAIDs and reduces the dose of GC in a third of patients.
The Incidence of Opioid Use in Patients Undergoing Orthopaedic Oncology Surgery
Authors:   Department of Orthopedic Surgery, Cooper University Hospital, Camden, NJ, USA, J Gutowski Christina , J Amin Sheena ,   Drexel University College of Medicine, Philadelphia, PA, USA
Published: July 2022

Objective: Primary or metastatic cancer can cause debilitating pain. Despite societal concerns regarding opioid use and abuse, opioid utilization patterns in orthopaedic oncology patients is not well-described. The purpose of this study is to determine patterns of opioid use in orthopaedic oncology patients and to identify factors associated with chronic use postoperatively.
Karl Jaspers, Siegfried Giedion, Pierre Teilhard de Chardin
Authors: Grosos Philippe
Published: July 2022

Par-delà leurs irréductibles différences, le philosophe Karl Jaspers, l’historien d’art Siegfried Giedion et le théologien Pierre Teilhard de Chardin ont ceci de commun qu’en élaborant chacun une pensée de l’histoire, ils ont su porter attention au concept de « préhistoire ». Et ils l’ont fait à une époque où seuls les préhistoriens s’intéressaient à la question. Que nous apprennent leurs analyses ? En quoi nous permettent-elles, aujourd’hui, de remettre en question l’opposition ordinairement admise entre histoire et préhistoire ? Peut-on voir en ces pensées un appel à refonder une philosophie de l’histoire ?
PENSAMENTO SEMIÓTICO SOBRE A CULTURA
Authors: MACHADO IRENE
Published: July 2022

sistemas semióticos, modelização, texto da cultura, dialogia, Ümwelt, semiosfera
Ecce Homo: um exercício de pseudoepigrafia sofista
Authors: Barbosa Rodrigo Francisco
Published: July 2022

Nossa hipótese é a de que há elementos discursivos no livro Ecce Homo que configuram-no como um exercício de pseudoepigrafia sofista. Para tanto, investigamos dois elementos específicos: em primeiro lugar, discutimos uma marcada tensão em Nietzsche com uma “disposição cética” (Skepsis) que, apesar de sua forma inicial como um “pirronismo histórico”, parece perpassar seu pensamento como radicalização da crítica da historiografia; em segundo lugar, e, complementarmente, exploramos o funcionamento de um tipo de discursividade em Ecce Homo que permite-nos interpretá-la como um exercício de pseudoepigrafia sofista. Trata-se, por fim, de verificar se os desafios da tensão da “atitude radical frente a possibilidade de atribuir confiabilidade aos testemunhos históricos” de Nietzsche, são balizados por uma instrumentalização material da linguagem que imita “catastroficamente” o gesto sofista de fabulação-invenção de uma narrativa “monumental” de si como pseudoepigrafia.
O cuidado de si, a meditação zazen e o ensino prático da filosofia.
Authors: Picoli Arlindo Rodrigues
Published: July 2022

Nesta pesquisa efetuamos uma investigação especulativa baseada no estudo e em experiências interpretativas de texto de Michel Foucault e Pierre Hadot. Partimos da hipótese de que o modo de vida praticado no Zen conseguiu preservar técnicas milenares, muito parecidas com os exercícios (askesis) praticadas na filosofia antiga e que só conhecemos por referências parciais e pouco detalhadas nos textos filosóficos. Nosso objetivo é investigar os conceitos de cuidado de si mesmo em Foucault e exercícios espirituais em Hadot, efetuar a comparação com o zazen e pensar no ensino de filosofia enquanto disciplina prática.
O problema da liberdade na passagem da arqueologia à genealogia foucaultiana
Authors: Noto Carolina de Souza
Published: July 2022

Em A arqueologia do saber, Foucault deixa claro que não é tarefa da arqueologia pensar a origem de uma formação discursiva, pensar como nasce a normatividade de certos usos da linguagem e como é possível que essa normatividade seja modificada por meio de uma ação livre. No presente artigo, procuraremos compreender os limites metodológicos que impedem a arqueologia tratar do tema da liberdade e indicar que a dificuldade dessa questão marca, na obra de Foucault, a passagem do método arqueológico ao genealógico.
La carne del feto. Riflessioni sul prenatale attraverso Merleau-Ponty
Authors: Di Clemente Fabio
Published: July 2022

Ci prefiggiamo di mettere a fuoco il concetto di carne del feto, indicando alcune centrali dinamiche ontologiche che il prenatale trascina con sé. In questo saggio continuiamo il nostro dialogo critico con Merleau-Ponty. Da un lato, tentiamo di coerentizzare ulteriormente il prenatale, pensato dalle scienze, nell’ontologia merleau-pontiana; dall’altro, cerchiamo la coerentizzazione dell’ontologia merleau-pontiana dal lato del prenatale.
A Study on the Structural Relationship between Perceived Career Barriers, Willingness to Implement Career Tasks, and Career Decision Level in the COVID-19 Pandemic Situation
Authors:   The Foodservice Management Society Of Korea, Son Eun-Soo , Lee Seung-Hoo
Published: July 2022

This study attempted to investigate the structural relationship between career barrier perception, willingness to perform career tasks, and career decision level for college students majoring in cooking. The sample of the study was college students majoring in cooking, and a total of 257 survey responses were used for the survey. As an analysis tool, the hypothesis was verified through confirmatory factor analysis and structural equation model analysis using the SPSS and AMOS programs. To summarize the research results, first, among the career barrier factors, lack of necessity, lack of self-clearness, and indecisive personality showed a negative (-) effect on the willingness to execute the career task, and anxiety about the future showed a positive (+) effect. Second, the willingness to perform career tasks had a positive (+) effect on the level of confidence in the career, and a negative (-) effect on the level of career undecided. Third, indecisive personality and lack of self-clearness were found to be factors that hinder career decision. Therefore, career barriers caused by COVID-19 suggested that internal factors are a greater risk factor for students' will and career decisions than external factors, and suggested the need for comparison and programs to awaken career preparation and self-clearness.
Átalakuló politikai spektrum a szlovén parlamenti választások után
Authors: Németh Ferenc
Published: July 2022

A 2022 áprilisában tartott szlovén parlamenti választásokon magabiztos győzelmet arató Robert Golob és az általa vezetett Szabadság Mozgalom alakíthatott új kormányt. Golob sikere mögött a Janez Janša egykori miniszterelnökkel szembeni elégedetlenség mellett a középbaloldali szavazók egy politikai tömörülésben való egyesítésének sikere is áll. Kérdéses, hogy Golob valóban stabilizálni tudta-e a szlovén baloldalt, vagy népszerűsége csupán tiszavirág-életű lesz.
Fifth Industrial Revolution
Authors: Ali Sabah Hameed , Al-Sultan Hayder Ayad , Al Rubaie Mithaq Taher
Published: July 2022

While we are rushing towards the future quickly and without stopping, there is a debate in the scientific community and business forums today about the upcoming industrial revolution and what it is related to, is it the revolution of artificial intelligence, or the revolution of nanotechnology, or the revolution of sustainability, or is it the revolution of the Internet of things, cloud computing and 3D printing? We believe that the Fifth Industrial Revolution will be the result of all these technologies. And through our research paper, we will address the concept of the industrial revolution in general and the major industrial revolutions in human history and their historical context. Then we will look at the Fourth Industrial Revolution, whose events we are living today, its most important technologies, and its future development. Then we will look at the future features of the upcoming Fifth Industrial Revolution and the controversy surrounding it from the point of view of several experts and the most important opportunities and challenges that are likely to emerge
Homo-Hetero Pairing Effect Correlation Coefficient
Authors: Bundala Ntogwa Ng’habi
Published: July 2022

The study aimed to examine the pairing relationship between economic growth and psychological human behavior (psychological well-being) of the individuals by application of the homo-hetero pairing effect correlation coefficient technique. The cross-sectional data were used. The data were collected from 211 individuals randomly sampled from two regions in Tanzania. The data were analysed by homo-hetero pairing effect correlation coefficient and the results were compared to that of the Pearson correlation coefficient and simple regression model. The study found that economic growth and psychological well-being are positively changing in pairs, and the psychological well-being of the individual is the true enabler (optimal independent) of the linear modelling. The study concluded that the improvement of the psychological well-being of individuals significantly improves economic growth and not vice versa. Therefore, the paper recommended that psychological well-being-based initiatives should be established and encouraged in society as found to have a positive impact on economic growth. Moreover, the study specifically, recommends the application of the homo-hetero pairing correlation coefficient in studies of cardiology, neurology, epidemiology, psychology, economics, anthropology, sociology and other fields of the social sciences.
The Effect of Competence, Job Placement and Job Satisfaction on Employee Performance at the Regional Office VII BKN
Authors: Sartika Lusi , Fatimah Fatimah , Asiati Diah Isnaini
Published: July 2022

This study aims to determine and analyze 1) the effect of competence, job placement and job satisfaction on employee performance at the Regional Office VII BKN, 2 ) the effect of competence on employee performance at the Regional Office VII BKN, 3) the effect of job placement on employee performance at the Regional Office VII BKN and 4) Job Satisfaction on employee performance at Regional Office VII BKN. The object of research is the employee at the Regional VII BKN office. The research method is associative using primary data. The population of this study was 140 employees, the sample selection technique used in this study was a probability sampling technique with a cluster random sampling method obtained through the formula of Isaac and Michael as many as 100 employees. The analysis technique used is multiple linier regression analysis. The results showed tha 1) simultaneously competence, job placement and job satisfaction had a significant effect on employee performance at Regional Office VII BKN, 2) competence had a significant effect on employee performance at Regional Office VII BKN, 3) job pacement had a significant effect on employee performance. At Regional Office VII BKN 4) job satisfaction has a significant effect on employee performance at Regional Office VII BKN
The Effect of Socialization of SAK EMKM, Accounting Understanding, and Level of Readiness of MSME Business Actors towards the Application of SAK EMKM in the Preparation of MSME Financial Reports (Case Study of MSMEs in Palembang City)
Authors: Saputra Yogi Darma , Anggraini Leriza Desitama , Sayadi Muhammad Hamdan
Published: July 2022

This study aims to analyze the influence of SAK EMKM socialization, accounting understanding, and the readiness of MSMEs actors to the application of SAK EMKM in preparing financial reports on MSMEs in Palembang city. The data used in this study were primary data obtained from questionnaires. The research method used is multiple linear regression analysis. The results prove that SAK EMKM (X1) has a negative effect on the application of SAK EMKM (Y). Meanwhile, understanding of accounting (X2) and the level of readiness of business actors (X3) have positive effect on the application of SAK EMKM (Y). This research is expected to help SMEs in preparing financial reports
A GESTÃO DO EFETIVO POLICIAL MILITAR INDISPONÍVEL PARA A ATIVIDADE FIM
Authors: Silva Jefferson , Cruz de Paulo Fabio Jose
Published: July 2022

O presente artigo tem como escopo propor uma mudança de postura dos gestores de unidades policiais, no sentido de otimizar o recurso humano indisponível para a atividade fim. Para tanto, realizou-se uma pesquisa bibliográfica acerca do tema saúde mental, bem como levantamentos estatísticos junto ao órgão competente da gestão dos afastamentos médicos da Corporação, a junta Médica - JM, onde ficou evidenciado que o problema permeia todo a Polícia Militar do Paraná (PMPR), demandando de seus Gestores uma maior responsabilidade na gestão desse efetivo, promovendo a sua reinclusão ao serviço policial, observadas suas limitações laborais. Após pesquisa, identificou-se que a Instituição PMPR buscou normatizar questões de afastamentos médicos, criando mecanismos de controle e gestão apenas quanto aos afastamentos médicos, estando ausentes mecanismos para a reinserção desse policial militar em recuperação de sua saúde.
Simultaneous determination of four organic acids in beverages by capillary electrophoresis coupled with ultraviolet detector
Authors: Bui Quang Dong , Arina Ivanova , Siyuan Qiu , Ingela Lanekoff ,   Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden; National Institute for Food Control, Hanoi, Vietnam,   Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden,   Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden,   Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden
Published: July 2022

A simple and rapid capillary electrophoresis method with direct ultraviolet (UV) detection was set up for the determination of four organic acids in beverages. The method included dilution and filtration as simple sample preparation steps. The electrophoretic separation and detection of oxalic, malic, citric and lactic acids in wines and beers were performed in 8 min. For the method validation, linearity, detection and quantification limits, repeatability and recovery in wine and beer matrices were studied. Good linearity was observed from 25 to 500 mg/L for all acids excluding lactic acid, for which it started from 50 mg/L. The limits of quantitation of oxalic, malonic and citric acid were set 9.5 to 28.5 mg/L. Repeatability of this method was from 3.2 to 7.3%, recoveries ranged from 90.1 to 110.1%. The validated method was applied to the analysis of different wines and beers and showed great variability in their composition.
Determination of some Aristolochic acid and Aristolactam in herbal dietary supplements containing Aristolochiaceae plants
Authors: Nguyen Thi Minh Hoa , Dang Thi Hien , Nguyen Thi Hong Ngoc , Tran Cao Son , Kim Thi Thanh Hien , Pham Thi Thanh Ha ,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   Hanoi University of Pharmacy, Hanoi, Vietnam,   Hanoi University of Pharmacy, Hanoi, Vietnam
Published: July 2022

LC-MS/MS method providing high sensitivity for determination of five aristolochic acids (AA) and four aristolactams (AL) was built. Samples were extracted efficiently in Methanol: DMSO solvent. The detection limit of AA A, AL BII is 0.030 ng/g, of AL FI, AL AII is 0.15 ng/g, and of AA B, AA C, AA D, 7-OH AA A, AL I is 3.0 ng/g. Recoveries of nine target compounds were from 80.2 to 110%, and relative standard deviations were below 10.5%. The method was applied to simultaneously determine the content of nine target analytes in capsule, tablet, traditional round pill, and liquid herbal supplements collected from different drug stores in Hanoi, Vietnam. Results show that AA A, 7-OH AAA, and AL I compounds exist in 24 out of 30 health supplements. Among them, it is worth noting that three tablet samples without declaring ingredients belonged to Aristolochiaceae plants on the pack, but still be positive with AA A and AL I.
Probiotic characteristics of Bifidobacterium infantis isolated in Vietnam
Authors: Bach Thi Nhu Quynh , Ninh Thi Tuyet Lan , Nguyen Thi Minh Huyen , Do Thi Men , Pham Thi Le , Mai Thi Dam Linh ,   Hai Phong University Medicinal and Pharmacy, Hai Phong, Vietnam,   Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam,   Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam,   University of Science, Vietnam National University, Hanoi, Vietnam,   University of Science, Vietnam National University, Hanoi, Vietnam,   University of Science, Vietnam National University, Hanoi, Vietnam
Published: July 2022

Bifidobacterium is anerobic bacterium which is popular in human and animal intestine. B. infantis was successfully isolated from a new-born child’s fecal sample previously. In this study, the probiotic characteristics of this strain such as: extracellular enzyme production ability; antibiotic activity against food-born pathogen like E. coli, S. aureus; organic acid production and bile-salt sufferance were evaluated. The results showed that the isolated can produce amylase and protease enzyme, do not produce cellulase enzyme; the organic acids also were produced during development of bacterium. The bacterium can against E. coli and S. aureus and can grow in the media containing up to 1% of bile salt. Results of this study are the basis for further studies to apply these bacteria as a source of probiotic beneficial to human health in Vietnam.
Asymptomatic malaria infection impact on maternal anemia in Delta State, Nigeria
Authors: Sally Obi Sadiatu , Davies W Sumner , Tiana Garrett-Cherry , Aondofa Adebe Gabriel , Ohwonigho Adjekuko Collins , Ikechukwu Nze Francis , Ann Odili-Igba , Ogirisen Felix , Dele Ajani
Published: July 2022

Background and Purpose: Pregnant women are vulnerable due to the pregnancy-induced suppressed immunity in malaria-endemic areas. Asymptomatic malaria in pregnancy (MiP) threatens both the mother, fetus, and neonate via chronic placental malaria which impacts maternal-neonatal exchange. Some studies reported that MiP risk factors vary across locations, however, there are few studies on MiP and maternal anemia in Nigeria. The purpose of this study was to investigate the association between asymptomatic placental malaria infection and maternal anemia among parturients in Asaba, Delta State, Nigeria.

Method: This study was developed with a quantitative methodology that utilized primary and secondary healthcare data from 483 subjects aged 18–49 years from four healthcare facilities between May and July 2021. The Socio-Ecological Model (SEM) framework was used to explain how parturients can achieve improved pregnancy outcome via the mobilization of multi-levels supports to enhance the compliance of parturients to malaria interventions. The research question and hypothesis were tested with the binomial logistic regression test.

Result:  The findings showed a statistically significant association between placental malaria parasitemia by microscopy (PMPM), intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine, use of complementary and alternative medicine (CAM), and  maternal anemia in the study population. Also, the study revealed that positive PMPM, use of  CAM, insecticides treated net (ITN) ownership, ITN frequent use, and antenatal care (ANC) attendance were the risk factors of maternal anemia among the study population.

Conclusion: The findings of this study could inform malaria control policymaking in Asaba and Delta State on tracking and treating asymptomatic placenta malaria among underserved parturient accessing antenatal services.
Propozycja nowoczesnej ramy konceptualnej do zarządzania ryzykiem w rolnictwie A proposal for a modern conceptual framework for risk management in agriculture
Authors: Kulawik Jacek
Published: July 2022

Współczesne rolnictwo wystawione jest na różnorodne szoki zarówno negatywne (ryzyka czyste), jak i pozytywne (ryzyka spekulatywne), a więc i szanse rozwojowe. Zatem z jednej strony oddziałują na nie zagrożenia zewnętrzne, z drugiej strony sektor ten generuje jednak zmienność w dolnych ogniwach łańcuchów żywnościowych. W związku z tym najpierw dokonuje się przeglądu współczesnych źródeł ryzyka w rolnictwie oraz ich rodzajów, akcentując duże znaczenie ryzyk operacyjnych i strategicznych oraz ich ujęć jako łańcuchów i sieci. Takie podejście pozwoliło przejść do zarządzania ryzykami na poziomie pojedynczych gospodarstw rolniczych. Ponieważ ryzyka ulegają agregacji w skali całego sektora rolnego, jak również na tym szczeblu pojawiają się ryzyka nowe, potrzebne było przeanalizowanie występujących tu problemów. Najlepszą ramą wydaje się w tym przypadku holistyczne/zintegrowane zarządzanie ryzykiem. Takie połączenie perspektywy mikro z perspektywą sektorową jest novum w krajowej ekonomice rolnictwa, a tym samym tworzy naukową wartość dodaną. W ślad za tym zrealizowano podstawowy cel artykułu i potwierdzono założoną tezę. Słowa kluczowe: holistyczny system zarządzania ryzykiem w rolnictwie, ryzyko, ryzyko w rolnictwie, zarządzanie ryzykiem w rolnictwie.
Polskie ubezpieczenia gospodarcze wobec zjawisk katastroficznych, w tym pandemicznych (wpływ zdarzeń katastroficznych na rynek ubezpieczeń rolnych)

Polish business insurance with reference to the catastrophic phenomena, including pandemic ones (impact of catastrophic events on the agricultural insurance market)
Authors: Nowak Stanisław , Nowak Radosław
Published: July 2022

Pandemia koronawirusa SARS-CoV-2, również na kontynencie europejskim,
spowodowała chorobę, śmierć milionów ofiar oraz poważne straty materialne. W Polsce,
podobnie jak w innych państwach, istotnie wpłynęła na rynki finansowe, a wśród nich
na sferę funkcjonowania ubezpieczeń gospodarczych, których elementem są dobrowolne i obowiązkowe ubezpieczenia rolne.
Przedmiotem niniejszego opracowania jest przegląd i sygnalizacja kryzysowych
oddziaływań zjawisk katastroficznych, także dotyczących ryzyka pandemicznego, na życie społeczne i gospodarcze kraju, w tym wpływu na obszar związany z funkcjonowaniem ubezpieczeń dla rolnictwa.
Analizie poddano przede wszystkim kwestie klęskowego oddziaływania katastrof
naturalnych, ze szczególnym uwzględnieniem zjawiska pandemii oraz udziału
ubezpieczeniowej metody kompensacji szkód i jej skutków materialnych.
Analizę uzupełniają wnioski i propozycje autorów, co do zadań i form działania
państwa, instytucji międzynarodowych oraz rynku ubezpieczeń w przypadkach wielce
prawdopodobnych, kolejnych tego typu zjawisk.
Celem opracowania jest ocena wpływu metody ubezpieczeniowej na zarządzanie
i przeciwdziałanie rodzajom ryzyk katastroficznych, w tym pandemicznych.

Słowa kluczowe: COVID-19, ryzyka pandemiczne, ubezpieczenia rolne, zarządzanie
ryzykiem katastrof naturalnych, zjawiska katastroficzne.
Kwarantanna a izolacja

Isolation and quarantine
Authors: Maciejewska Katarzyna
Published: July 2022

Izolacja i kwarantanna to dwa terminy, które towarzyszą nam od początku pandemii.
Niniejszy artykuł omawia, jakie świadczenia przysługują ubezpieczonym rolnikom
(domownikom) z tytułu objęcia obowiązkową kwarantanną, nadzorem epidemiologicznym,
hospitalizacją w związku z COVID-19 lub izolacją domową. Artykuł ma na celu
zaprezentowanie ogólnych zasad i warunków przyznawania ww. świadczeń, kręgu osób
uprawnionych do ich uzyskania oraz zasad ustalania ich wysokości. Przedstawia zbieg
prawa do zasiłku z tytułu kwarantanny z prawem do zasiłku chorobowego oraz pojawiające
się w związku z tym wątpliwości. Autorka zwraca uwagę na rozbieżności w świadczeniach
otrzymywanych z KRUS przez rolników w przypadku zachorowania bądź podejrzenia
zakażenia COVID-19. W podsumowaniu wskazuje najważniejsze wnioski płynące z badań.

Słowa kluczowe: hospitalizacja, izolacja domowa, kwarantanna, rolnik, zasiłek
Reconfigurable Inverted U Slot Antenna with Switching Mechanism for Wireless Applications
Authors: Sowjanya Kesana  , Arunabala C  , V. Sai Lalitha Sri Harshini  , T. Priyanka  , P. Nikhitha  , V. Swetha
Published: July 2022

Frequency reconfigurable antennas are mostly used for many wireless applications. The proposed antenna uses a PIN diode to switch between 2.45 to 3.93 GHz. The ultra-wideband is obtained by a partial rectangular ground plane with an inverted U slot and the narrowband is obtained by adding a parasitic element electrically connected to the ground by positive bias of PIN diode. Frequency Reconfigurable antennas can adjust dynamically its frequency of operation as per the requirement. For better designing of antenna and to get better accurate results, we usually change the physical dimensions of the antenna. It is lengthy and time taking process if we consider this method. Comparison and selection in designing of antennas will be difficult if we keep on changing the dimensions. So, we prefer Reconfigurability.
Authors: Restrepo-Arango Cristina , Cárdenas-Rozo Andrés L.
Published: July 2022

Este trabalho aplica a análise textual a cinco artigos paleontológicos sobre fósseis colombianos, a fim de identificar a proximidade lexical em um corpus de textos. Este trabalho permitiu determinar: as categorias gramaticais, a proximidade entre categorias de palavras e variáveis ​​com a análise de especificidades (AE), o agrupamento das palavras com a análise da classificação hierárquica descendente (CJD) e a apresentação gráfica das palavras. Verificamos que o corpus documental é composto por 31.319 ocorrências de palavras, 1.450 formas ativas ou palavras específicas e 303 formas complementares ou palavras comuns. A categoria gramatical de substantivo predomina (24%) e palavras não reconhecidas no dicionário (17%). As palavras comuns com maior número de frequências são artigos, conjugações, proposições e pronomes. Constatou-se que existe uma proximidade lexical entre o artigo 1 e as formas ativas de “Colômbia” e o artigo 2 e as formas ativas de “fóssil”. As palavras foram agrupadas em cinco classes e a nuvem de palavras foi criada com 1271 palavras
A matemática presente no curso de Licenciatura Plena de Ciências com habilitação em Matemática para a formação de professores da Universidade Estadual de Feira de Santana-Bahia (1986-1988)
Authors: Lima Eliene Barbosa , Silva Maria Inês da Luz , Oliveira Matheus Brandão
Published: July 2022

Neste texto, investigou-se, em uma perspectiva histórica, a matemática presente na formação do professor da Licenciatura Plena em Ciências da Universidade Estadual de Feira de Santana com habilitação em Matemática, por meio de documentos históricos, sobretudo cadernos de aulas, pertencentes a Josenildes Oliveira Venas, estudante desse curso entre 1986 e 1988. Tal investigação foi norteada pela seguinte questão: qual era a matemática presente no curso de Licenciatura Plena de Ciências com habilitação em Matemática para a formação de professores da Universidade Estadual de Feira de Santana-Bahia, no período de 1986 a 1988? Para tanto, fez-se uso de uma literatura vigente no âmbito da história da educação matemática, de um modus operandi da história cultural e de fontes históricas. Como resultados, constatou-se que a matemática do ensino, presente na formação desse professor, estava a serviço do próprio campo disciplinar, tendo pouca ou nenhuma articulação com a matemática ensinada nas escolas. Ela era tomada, sem uma dinâmica própria, isto é, como uma mera reprodução didatizada de saberes matemáticos que estavam sendo ensinados nas instituições de nível superior, contrariamente ao que acontecia na Licenciatura Curta, onde predominou uma matemática do ensino sob uma articulação entre a matemática da formação de seu professor e aquela que estava presente no ensino.
Didática hoje: entre o “normal”, o híbrido e a reinvenção
Authors: Candau Vera Maria Ferrão
Published: July 2022

A pandemia de Covid-19 afetou diferentes dimensões da vida social, tais como a economia, o comércio e o setor produtivo, as relações sociais e familiares, as atividades esportivas e recreativas, entre outras. As desigualdades sociais, já presentes na nossa sociedade, se reforçaram. Certamente, os processos educacionais foram fortemente afetados. Muitas e plurais foram as questões enfrentadas pelos sistemas de educação, escolas, professores/as, alunos/as, famílias, nos diferentes níveis de ensino. Situando-nos na perspectiva da pós-pandemia, podemos nos perguntar: Que escola somos chamados a construir/reconstruir? Que dinâmicas escolares queremos privilegiar? Que desafios essas questões suscitam para a Didática? Essas são as provocações que orientam o presente texto. Nele, pretendemos abordar algumas alternativas que permeiam as discussões atuais sobre essa problemática, que sintetizamos da seguinte maneira: a volta à escola “normal”, a escola informada pelo “ensino híbrido” e a “reinvenção” da educação escolar. Analisamos cada uma delas no que se refere a suas implicações para os processos de ensino-aprendizagem e defendemos a posição de que vivemos um momento privilegiado para repensar o papel da escola e da Didática em novas configurações e perspectivas, numa abordagem crítica e intercultural.
Alluded meaning of a legislative text (isharat al-nass) in the hanafi school of law
Authors: Ramić Šukrija
Published: July 2022

This paper examines the Hanafi scholars’ approach to the alluded meaning
(isharat al-nass) of a legislative text, and the implications of such an approach for the legal norms the Hanafis derived through ijtihad. The first part of
the paper discusses the issue of possible textual indications (al-dalalat) within a legislative text, and then the concept of allusion in the Hanafi School
from the linguistic and terminological point of view. Providing the examples
of alluded meaning we show the way in which the Hanafis used alluded
meanings in their argumentation. We also elaborate on the status of isharat
al-nass in the Hanafi Madhab, and the way of giving preference in case of
contradiction between isharat al-nass and ibarat al-nass. At the end of the
paper we provide the conclusions derived from the study.