bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Safety Leadership in the Influence of Safety Coaching and Safety Engagement on Safety Performance
Authors: Hermawan Febrian , Setyawan Agustinus , Sudhartio Lily
Published: December 2024

Occupational safety and health professionals play an important role in improving workplace safety. However, the effectiveness of safety leadership, safety coaching and engagement in improving safety performance, mediated by safety culture, remains under-researched. This study aims to analyze how these factors influence safety performance among occupational safety and health professionals in Riau Islands Province, Indonesia. This study used a structural equation modelling (SEM) approach for hypothesis testing based on data collected from 180 active occupational safety and health professionals using purposive sampling. The results showed that all hypotheses were supported: safety leadership mediated the relationship between safety training and safety engagement with safety performance. This suggests that leadership is important in fostering a safety culture and encouraging proactive employee engagement. In addition, safety training was found to significantly influence leadership and safety performance. The results of this study conclude that strengthening leadership and engagement in safety through targeted coaching and training can significantly improve safety outcomes in high-risk industries. The findings underscore the importance of integrating safety leadership and culture into organizational practices. Future research should explore the long-term impact of safety leadership interventions and the potential for cross-industry application to further improve workplace safety standards.
Analisis Kritis Etika Politik Kasih Tinjauan Fratelli Tutti 154 Perang Melawan Politik Individualisme
Authors: Aliano Yohanes Alfrid , Welan Yeremia Anton Julianus , Lau Stefanus , Arianto Josep
Published: December 2024

This study discusses the phenomenon of the "Politics of Love" as a response to the increasing politics of individualism in the context of critical analysis of Political Ethics, with reference to the views expressed in Fratelli Tutti's encyclical 154. The background of this research involves concerns about globalization which increasingly emphasizes individualism in dynamics. Politics, which can threaten the principles of social solidarity and bonum commune. The main objective of this research is to identify the key elements of the concept of "Politics of Love" advocated by Fratelli Tutti as an alternative to the politics of individualism. The method used involves critical text analysis of the 154 encyclicals, with a focus on historical context and in-depth theological interpretation. The results of this study reveal that the "Politics of Love" advocates the adoption of a more inclusive, collaborative, and caring approach to the common good. This includes rejecting narrow views that only prioritize the interests of certain individuals or groups. This research also highlights the importance of moral leadership in promoting solidarity, shared prosperity, and the spread of human values. This research shows that in facing the political challenges of increasingly strong individualism, the concept of "Politics of love" can be an ethical guide that has the potential to restore the principles of inclusiveness and mutual care in the world of politics. By referring to the teachings of Fratelli Tutti, this research underscores the need for a transformation in the political paradigm towards an approach that is more oriented towards love, equality and social justice for the common good.
Contra Legem Pembagian Harta Bersama Perspektif Maslahah Murshalah
Authors: Zuhriandi Novrizal , Lubis Fauziah , Nurcahaya Nurcahaya
Published: December 2024

Of the many impacts that occur from the breakdown of a marriage, one of them is the problem of dividing joint assets. Where joint assets are assets acquired by a husband and wife while they were still married. In decision NO.2802/Pdt.G/2018/PA.Dpk, the Depok Religious Court Judge gave a larger share of joint assets to the ex-wife, with details of 70% for the ex-wife and 30% for the ex-husband. Meanwhile, Article 97 of the Compilation of Islamic Law explicitly provides for shares of joint assets in equal amounts between the wife and husband. Where the judge clearly ignored written Material Law, namely the Compilation of Islamic Law, in deciding the case. This research aims to find out the basic considerations of the Depok Religious Court judges in deciding this case, and how the KHI and Islamic law are reviewed from Maslahah Murshalah's perspective on resolving the joint property problem. This research is normative juridical research. This type of research is library research. The results of the research illustrate that the judge decided the case by giving a share of joint assets in both the Convention and Reconvention decisions in the amount of 30% for the Convention Plaintiff/Reconvention Defendant and 70% for the Convention Defendant/Reconvention Plaintiff. In this decision the judge adopted jurisprudence, more precisely, Supreme Court Decision No.266/K/AG/2010 as a legal consideration in deciding the case, however the judge also made legal discoveries using independent legal methods in determining the amount obtained by each partner, because in In this decision, the judge did not fully adopt the Supreme Court's jurisprudence, but rather, chose to dig deeper into the ins and outs of the assets, roles and contributions of the couple during the marriage period.
Praktik Kesalehan Pemuda pada Kota Provincial
Authors: Rizkidarajat Wiman , Mutahir Arizal , Hanny P Isna , Putri M Aulia , Romauli Nethania
Published: December 2024

Since the New Order collapsed in 1998, Islamization in Indonesia has become a mainstream movement. Evidence of mainstreaming Islamization is the increasingly common practice of piety in public spaces. One of the most common Islamization efforts is efforts to purify Islam through hijrah movement carried out by youth groups through popular culture media, such as through music in metropolitan cities in Indonesia such as Jakarta, Bandung and Yogyakarta. The hijrah movement is often carried out by targeting young people who have experienced transgressive life practices, causing the exploitation of space. This research aims to portray the practice of piety that occurs in provincial cities or second-class cities in the city dichotomy, according to Van Klinken. The research method used in this research is descriptive qualitative with a case study approach. Ethnographic data collection was carried out for six months, from November 2023 to May 2024, with the primary data source being a youth study collective in Purwokerto called Majlis At Tho'at. The findings of this research are that the At Tho'at Assembly's pious practices are carried out by creating two types of space that came from youth creativity in term to redefined hijrah movement. The first is a private room in the form of exclusive recitations, which are held regularly in the residence of one of the assembly members. The second is public space in the form of piety exhibitions in public spaces through a band, which is formed through social interaction in private spaces through recitations. The research results show that piety in provincial cities does not always exist in a binary dichotomy, which results in the exploitation of space as occurs in metropolitan cities. This is proven by the existence of spaces to negotiate a social phenomenon that occurs in a city.
Peran Coenrad Laurens Coolen sebagai Pemimpin Desa Kristen Ngoro Jombang 1827-1844 serta Nilai-Nilai Edukasinya
Authors: Bastyan Habiby , Jati Slamet Sujud Purnawan
Published: December 2024

Historical studies often reveal the role of figures in shaping the thought patterns and behavior of past people. One interesting example is Coenrad Laurens Coolen's role as the leader of the Ngoro Christian Village in Jombang. In 1827-1844, coenrad laurens coolen, a half-Javanese European, formed the Ngoro Christian Village. Coolen played the role of leader of the Ngoro Christian Village. Apart from developing the village's physical infrastructure, Coolen also strengthens the community's spiritual dimension with humanist Christian teachings. Coolen understands Javanese society and teaches Christian teachings using a Javanese cultural approach. This means that Coolen was not only a pioneer of Christian teaching in Java, but also combined these teachings with Javanese culture, making it more easily accepted by the local community. The research method used in writing this article is a historical research method with a descriptive qualitative approach to investigate the role of Coenrad Laurens Coolen as leader of the Ngoro Christian Village and the educational values ​​reflected in this process. Coenrad Laurens Coolen played an important role in the Christian Village of Ngoro, Jombang, from 1827 to 1844. It was found that Coolen, who had a Dutch-Javanese background, made it easier for him to spread Christianity through a Javanese cultural approach. Coolen played a role in developing Ngoro Village physically and spiritually, as well as educational values ​​in his leadership that are in accordance with the six dimensions of the Pancasila Student Profile, namely faith and noble character, global diversity, mutual cooperation, independence, critical reasoning, and creativity. Coenrad Laurens Coolen's role as leader of the Ngoro Christian Village in Jombang from 1827 to 1844 shows educational values ​​that are relevant to the Pancasila Student Profile. So Coenrad Laurens Coolen's role as leader of the Ngoro Christian Village in Jombang from 1827 to 1844 can be used in history learning at school.
Makna Relief Pura Dalěm Kělod Sangsit Sebagai Media Pembelajaran Teologi Hindu
Authors: Putra I Wayan Sunampan , Ni Made Yunitha Asri Diantary , Windya Ida Made
Published: December 2024

Pura Dalěm Kělod Sangsit is a unique temple. The unique thing is that it is found in the reliefs carved on the walls of the Dalěm Kělod Sangsit Temple. Another interesting thing is the depiction of sexuality or scenes of sexual intercourse. The uniqueness there is different from the concept of holy places in general. Due to these problems, this research aims to explore the meaning of the reliefs of the Dalěm Kělod Sangsit Temple. The method is a qualitative approach taking the location in Sangsit Village, Sawan District, Buleleng Regency. The results of this research are; The reliefs of Pura Dalěm Kělod Sangsit provide various meanings. The meaning of Pura Dalěm Kělod Sangsit related to the Hindu Theology Study program is; a) Meaning of Hindu Theology; Pura Dalěm Kělod Sangsit as a worship of Lord Śiwa. Even in the reliefs at Pura Dalěm Kělod Sangsit, various manifestations of God are depicted as symbols of Hindu theology. b) The meaning of Exchatology can be seen from the appearance of the reliefs at Pura Dalěm Kělod Sangsit which depict human life when entering the world of spirits or the world of death. c) The didactic meaning can be seen from the existence of the reliefs at Pura Dalěm Kělod Sangsit which depict the teachings of karma phala. Karma phala is the concept of cause and effect. The appearance on the relief of Pura Dalěm Kělod Sangsit tells about the punishment for spirits who commit sins in the afterlife. Based on the meaning of the reliefs at Pura Dalěm Kělod Sangsit, it can be concluded that the reliefs of Pura Dalěm Kělod Sangsit have a deep meaning. Hence, they are relevant as a learning medium in the Hindu Theology Study Program.
Pembunuhan Bayi Dalam Alquran Perspektif Mufassir Nusantara dan Dampaknya Terhadap Gangguan Kesehatan Mental
Authors: Wita Rahma , Arifin Zainal , Matondang Husnel Anwar
Published: December 2024

Currently, many infanticides are carried out by their biological mothers, most of which are carried out in a planned manner. A mother is supposed to protect her baby, but this relationship is becoming less common nowadays. Many children receive bad treatment from their parents, even losing their lives. This research aims to explore infanticide in the Koran and analyze Indonesian interpreters' interpretations of the Koranic verses regarding infanticide and its impact on mental health disorders. This research uses qualitative methods with descriptive-analytic data analysis techniques. The results of this research show that murder is an act of taking human life. There are three words for murder in the Koran, namely, the word al-Qatl which totals 34 verses, the phrase al-Maut 1 verse, and the word fahisyah 8 verses. Furthermore, infanticide in the Koran, surah al-An'ām verse 151, and al-Isrā verse 31, according to Indonesian commentators, is the killing of girls for fear of poverty. Thus, the Koran has provided solutions to the factors that cause the murder of children, especially babies, so that this act can be avoided. In this case, Indonesian mufassir offers three solutions, namely giving alms, giving zakat, and abstaining from adultery. These three solutions have implementation for a person's mental health disorders, especially infanticide perpetrators who are worried about poverty.
Bidadari Surga Dalam Tafsir Fī Ẓilāl Alquran Karya Sayyid Quṭb
Authors: Chyta Dena Aria , Harahap Mardian Idris , Simamora Nur Aisah
Published: December 2024

The interpretation of heavenly pleasures is often seen as gender biased. Some pleasures of paradise are understood to be exclusive to one gender. However, gender is not a condition for entering paradise; such interpretations are about the heavenly maidens. This study aims to explore the descriptions of heavenly maidens in the Koran and analyze Sayyid Qutb’s understanding of the Quranic verses about the heavenly maidens. The research uses a qualitative method with descriptive-analytical data analysis techniques. The findings of this study reveal that the Quran describes the physical characteristics of the heavenly maidens with the word “ḥūr” paired with “’īn,” found in Surah Ad-Dukhan verse 54, Surah At-Tur verse 20, and Surah Al- Waqi'ah verse 22. At other times, the Quran uses the more general term “azwāj” (spouses) to describe the heavenly maidens. This word is mentioned 4 times, in Surah Al-Baqarah verse 25, Surah Ali ‘Imran verse 15, Surah An-Nisa verse 57, and Surah Yasin verse 56. Furthermore, in interpreting the heavenly maidens in the Koran, according to Sayyid Qutb, the expression “heavenly maidens” needs to be understood as an indication of their existence. According to Qutb, the word “ḥūr” refers to women with fair skin, and large eyes with white and black color complementing each other. As for the phrase “qāṣirāt al-Ṭarf atrāb,” it is interpreted as the women of paradise praised by Allah for their loyalty, always lowering their gaze and never looking away except towards their spouses. The term “azwāj muṭahharah” according to Qutb signifies the state of women being devoid of the negative qualities possessed by women in worldly life.
Fenomena Flexing Culture Di Media Sosial Mahasiswa Pendidikan Agama Islam
Authors: Jannah Raudhatul , Ajahari Ajahari , Lutfi Saiful
Published: December 2024

Islamic Religious Education students as future religious educators need to realize the importance of limiting the content shared on social media to maintain integrity and ethics in accordance with Islamic values. This is to keep activities on social media reasonable and not contradict their role as role models in society. This study aims to describe the motives of flexing culture of Islamic Education students at IAIN Palangka Raya on social media and find out how the phenomenon of flexing culture on social media of Islamic Education students according to the perspective of the Islamic Education crisis. The method used in this research is a qualitative approach using descriptive data. This research uses data collection techniques in the form of interviews and documentation, which are analyzed through data reduction, data presentation, and conclusion drawing. The results showed that the main motive of Islamic Religious Education students class 2020 class A semester 8 IAIN Palangka Raya behind this flexing culture is from internal encouragement, the phenomenon of flexing culture among Islamic Education students has two different sides in the context of the Islamic Education crisis. On the one hand, sharing academic achievements and positive activities can motivate and build a good self-image. However, if done with the intention to boast, this can reduce the quality of Islamic education and obscure religious values. There needs to be a higher awareness among Islamic Education students regarding the wise use of social media in order to avoid the potential for irritation, feelings of inferiority, and the development of negative perceptions among the community.
Pengelolaan Dana Punia Melalui Pengembangan Pendidikan Pasraman Dan Pemberdayaan Ekonomi Umat di Badan Dharma Dana Punia Raman Utara
Authors: Antara Dewa Putu , Tanaya I Nyoman Tri Bayu
Published: December 2024

Dana punia is a sacred activity as one of the implementations of the teachings of dharma. The purpose of this study is to determine the management system of Punia Funds through the development of pasraman education and empowerment of the people's economy carried out by BDDPRU and to determine the supporting and inhibiting factors for the development of Punia Funds for pasraman education and empowerment of the people's economy carried out by BDDPRU. With that, it will be possible to obtain a maximum fund management system by pasraman. In addition, this study is able to encourage and empower Hindus in the future. This research method is Qualitative and uses studies in accordance with Humanistic theory and the theory of Motivation to do business in the management of Dharma Dana. One of the supporting factors for BDDPRU is the existence of permanent punia funders, this supporting factor can provide a strong solution in the process of managing punia funds through the development of pasraman education and empowerment of the people's economy. One of the inhibiting factors is the lack of adequate facilities and infrastructure. In conclusion, the BDDPRU Punia Fund management system has used POAC (Planning, Organizing, Actuating and Controlling) management but has not been maximized.
Agama Hindu dan Budaya Bali: Warisan Luhur dalam Kehidupan Modern
Authors: Subawa Ida Bagus Gede
Published: December 2024

Religion, previously regarded as a shared source of values and social norms, is now increasingly understood as a personal reconstruction process reflecting individual freedom in interpreting religious teachings. In Bali, this phenomenon is evident in the evolving practices of Balinese Hinduism, influenced by modernization and globalization. Nevertheless, the Balinese Hindu identity remains preserved by most of the community as an integral part of their culture. Balinese Hinduism plays a crucial role in maintaining social and cultural harmony through the implementation of panca yadnya rituals and the Tri Hita Karana principles, which emphasize balance in relationships between humans, God, and nature. This study aims to examine the dynamics of changes in Balinese Hindu practices and explore their role in maintaining social and cultural harmony amidst the challenges of globalization. The method employed is a literature review, analyzing relevant academic sources to develop theoretical contributions toward the preservation of Balinese Hindu culture and religion. The findings reveal that despite the increasing influence of modernization, local religious practices such as panca yadnya remain central to Balinese life. The tri hita karana principles continue to serve as a foundational framework supporting cultural sustainability and social harmony in the face of changing times. In conclusion, the Balinese Hindu identity demonstrates significant resilience through the integration of local traditions with modern challenges. This study highlights the importance of preserving Balinese Hindu religion and culture as a means of safeguarding social harmony and local wisdom in the era of globalization.
Wayang Emas Di Bali Peradaban Budaya Hindu Nusantara
Authors: Linggih I Nyoman
Published: December 2024

The existence of wayang (shadow puppets) in the nusantara region dates back to 829 CE (907 AD), with its presence in Bali traced to 980 Saka (1058 AD). In modern times, the tradition of Wayang Emas (Golden Puppet) in Bali began in 2009. This study aims to explore the forms, functions, and meanings of Wayang Emas for the Hindu community in Nusantara. Data collection involved observations, literature studies, and interviews, analyzed through data reduction, data display, and conclusion drawing. The results indicate that Wayang Emas, crafted from pure yellow and white gold, is rooted in the Majapahit era. This unique tradition is linked to Prime Minister Gajah Mada's Palapa Oath, symbolizing the unification of nusantara under the Majapahit Kingdom in the 14th century. Wayang Emas exemplifies the advanced cultural and spiritual legacy of Hindu nusantara. It serves multiple functions: as an artistic expression, a medium of religious devotion, and a symbol of societal cohesion. Its sacred nature underscores the duality of physical and spiritual preservation, embodying cultural continuity while fostering faith in the oneness of God. In conclusion, Wayang Emas reflects the enduring influence of Majapahit Hindu culture and its ability to adapt to contemporary practices. As a tangible representation of unity and sanctity, it highlights the importance of safeguarding this heritage, ensuring its relevance for future generations while strengthening the spiritual and cultural identity of the Hindu community in nusantara.
The Impact of Strategic Orientations on Sustainable Performance: The Moderating Role of Business Intelligence at Jordanian Commercial Banks
Authors: Mahmoud Al Shawabkeh Khaled
Published: December 2024

Jordanian commercial banks are achieving sustainable performance by balancing economic, social, and environmental dimensions, aiming for long-term profitability, community development, and environmental awareness, which are crucial for the banking sector's continuity and development. The current study aims to investigate the impact of strategic orientations on sustainable performance and the moderating role of business intelligence at Jordanian commercial banks. This study collects the primary data from 218 managers at the top and middle levels of Jordanian commercial banks. This study utilized the Statistical Package for the Social Sciences (SPSS) to analyze hypotheses. The study revealed that strategic orientations (learning orientation, market orientation, digital orientation, and entrepreneurial orientation) had a statistically significant impact on sustainable performance at Jordanian commercial banks, with an explanatory power of (R2= 44.4%). It was also demonstrated that business intelligence had a statistically significant impact on improving the impact of strategic orientations on sustainable performance at Jordanian commercial banks, with an explanatory power of (R2= 45.3%). According to the results of the study, the most important recommendations for the banks surveyed are as follows: Jordanian commercial banks should adopt a sustainable strategy through their strategic orientations, focusing on social responsibility, environmental preservation, and environmental interest projects. They should utilize business intelligence, foster a sustainability culture, communicate with stakeholders, and continuously improve performance.
Factores que generan trastornos musculoesqueléticos en los profesionales de enfermería de la unidad de cuidados intensivos
Authors: Cuñez Fárez Diana Carolina , Sarango Carrión Karla Estefanía , Mejías de Duarte Marianela
Published: December 2024

Introducción: La unidad de cuidados intensivos es un área donde el profesional de enfermería
suple todas las actividades de pacientes críticos que han perdido su autonomía. Los factores:
ergonómicos, individuales, psicosociales o ambientales, predisponen al profesional a desarrollar
trastornos musculoesqueléticos. Objetivo: Determinar los factores que generan trastornos
musculoesqueléticos en los profesionales de enfermería de la unidad de cuidados intensivos.
Método: Metaanálisis que parte del análisis de 14 artículos seleccionados mediante palabras de
búsqueda, criterios de inclusión y exclusión en diferentes bases de datos. Se utilizó el algoritmo
PRISMA para representar el proceso de búsqueda y selección. Aspectos éticos: se respetó la
autoría de cada artículo. Resultados: Los factores de riesgo físicos o ergonómicos predominan
en el desarrollo trastornos musculoesqueléticos. El 92,85% mencionan al dolor como el principal
síntoma. Al desarrollar trastornos musculoesqueléticos, las zonas corporales afectadas que
prevalecen son: lumbar, hombro y cuello. Conclusiones: Los factores que generan trastornos
musculoesqueléticos en el profesional de enfermería, aumentan la incidencia de lesiones musculoesqueléticas,
por tanto, identificarlos es un trabajo multidisciplinario, que permita identificar
conductas que lo estén provocando y a partir de esto, generar intervenciones encaminadas
en implementar estrategias preventivas basadas en la ergonomía que garanticen al profesional
una enfermería laboral saludable.
Actuación del Personal de Enfermería en los Protocolos de Atención en Pacientes con Accidente Cerebro Vascular (ACV) isquémico en Áreas Críticas
Authors:   Universidad Iberoamericana del Ecuador, Ajila Enríquez Víctor Hugo , Chicaiza Pastillo Samia Verónica , Santiana Valdivieso Alexandra Valeria , Figuera Ávila Paolina Antonieta
Published: December 2024

El accidente cerebrovascular isquémico (ACV isquémico) es una de las principales causas de
muerte y discapacidad a nivel mundial, caracterizado por la obstrucción del flujo sanguíneo en
los vasos cerebrales, lo que provoca daño neuronal irreversible si no se trata de forma oportuna.
El factor tiempo es crucial para iniciar el tratamiento adecuado, y el personal de enfermería
desempeña un rol fundamental en la reducción de los tiempos entre la llegada del paciente al
hospital y el inicio de la terapia trombolítica, mejorando así los resultados clínicos. Este estudio
tiene como objetivo analizar el impacto de las intervenciones de enfermería en la atención de
pacientes con ACV isquémico en fase aguda, evaluando su efectividad en la administración
del tratamiento fibrinolítico (rt-PA) y en la mejora de los desenlaces clínicos. A través de una
revisión bibliográfica descriptiva de informes y artículos científicos obtenidos en bases de datos
como Google Académico, SciELO, Redalyc, Dialnet y Lilacs, se identificaron estudios que
abordan la intervención de enfermería en este contexto. Los resultados destacan que la capacitación
y el conocimiento del personal de enfermería influyen directamente en la eficacia del
manejo intrahospitalario del ACV isquémico, particularmente en la administración oportuna
de rt-PA dentro de la ventana terapéutica de 4.5 a 6 horas. Además, se observó una relación
costo-beneficio favorable del uso de rt-PA, especialmente en pacientes jóvenes y sin comorbilidades
severas, lo que refuerza la importancia de una intervención temprana. Sin embargo,
se reconoce la necesidad de investigaciones futuras para evaluar los efectos a largo plazo del
tratamiento trombolítico en diversos contextos clínicos y poblaciones.
Factores de riesgos de las Infecciones Asociadas a la Atención de salud relacionado con el catéter venoso central en pacientes críticos
Authors:   Universidad Iberoamericana del Ecuador, Valdez Ramón Yesy Esther , Yaguana Yaguana Jenny Cecibel , Alvarado Chacón Roberto Enrique
Published: December 2024

Las infecciones asociadas a la atención en salud (IAAS) son un problema global que afecta
especialmente a pacientes críticos en unidades de cuidados intensivos (UCI), donde el uso
de dispositivos invasivos como el catéter venoso central (CVC) es común. Aunque los CVC
son fundamentales para administrar medicamentos y líquidos, también representan un riesgo
significativo de infecciones, como las del torrente sanguíneo. Este estudio tiene como objetivo
principal identificar los factores de riesgo asociados al uso del CVC en pacientes críticos,
con el propósito de mejorar las estrategias de prevención y reducir la incidencia de IAAS. La
investigación se llevó a cabo mediante la metodología PRISMA 2020, utilizando una revisión
sistemática de literatura científica, incluyendo artículos, guías clínicas y protocolos de manejo,
seleccionados bajo criterios estrictos de inclusión y exclusión. Los resultados revelaron que
factores como la prolongada duración del CVC, la inserción en condiciones no estériles, la
falta de adherencia a protocolos de asepsia y el monitoreo inadecuado son determinantes en
el desarrollo de estas infecciones. Además, se identificaron intervenciones eficaces, como la
capacitación del personal, la implementación de bundles de prevención y la monitorización
continua de las prácticas clínicas. En conclusión, la identificación y mitigación de los factores
de riesgo asociados al CVC son esenciales para reducir las IAAS en pacientes críticos, mejorar
los desenlaces clínicos y garantizar una atención en salud segura y de calidad.
ДО ПИТАННЯ ЗАХИСТУ ТА ПІДТРИМКИ МЕНТАЛЬНОГО ЗДОРОВ’Я ОСІБ З ОСОБЛИВИМИ ПОТРЕБАМИ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Yarmola Nataliia
Published: December 2024

Події, що відбуваються у нашій країні, певною мірою торкаються всіх її громадян, всім потрібна допомога, підтримка, аби вистояти вберегти себе і близьких, зберегти своє емоційне й психічне здоров’я. У період війни найбільше зростають ризики безпеки дітей, особливо загострюються питання, що стосуються дітей-сиріт і дітей, позбавлених батьківського піклування, а також дітей з особливими освітніми потребами.У представленій статті розкрито основні проблеми осіб з особливими потребами (ООП) в умовах воєнного стану. Здійснено аналіз провідних світових досліджень ступеня впливу умов війни на ментальне здоров’я дитини, представлено офіційні статистичні дані щодо постраждалого дитячого населення України. Схарактеризовано наукові напрями діяльності Інституту спеціальної педагогіки і психології імені Миколи Ярмаченка НАПН України щодо психолого-педагогічного супроводу осіб з особливими освітніми потребами в умовах кризових викликів. Представлено результати наукових досліджень Інституту стосовно проблеми ментального здоров’я осіб з ООП та окреслено шляхи вдосконалення психолого-педагогічних досліджень в контексті інтеграції у європейський освітньо-науковий простір.
Kajian Penilaian Kondisi Fisik Hunian di Dalem Mangkubumen
Authors: Adianti Tina , Suharno YE
Published: December 2024

Dalem Mangkubumen merupakan bangunan yang terletak tidak jauh dari Kraton Yogyakarta. Dalem yang awalnya difungsikan sebagai hunian pangeran dari raja yang sedang bertahta, saat ini berkembang menjadi kawasan permukiman. Permukiman tersebut muncul dan berkembang karena keturunan pangeran dan abdi dalem tetap memilih tiggal di area tersebut, ditambah warga diluar abdi dalem. Hal tersebut salah satunya dipicu oleh posisi dalem Mangkubumen berada di pusat kota, sehingga permukiman tersebut tetap berkembang. Berdasarkan UU. No. 1/2011 tentang Perumahan dan Permukiman, diharapkan  kompleks Dalem Mangkubumen wajib memiliki sarana dan prasarana untuk upaya pemenuhan rumah yang layak huni.  Penelitian ini fokus pada penilaian kondisi fisik bangunan hunian berdasarkan indikator rumah layak huni. Penelitian menggunakan metode kualitatif, dengan pengambilan data observasi serta wawancara langsung dilapangan. Hasil penilaian nantiya dapat mengetahui kelayakan kondisi hunian, serta menunjukkan ketidak sesuaian menurut indikator hunian layak huni
Penerapan Critical Regionalism Pada Bangunan Marika Alderton House dan Museum Tsunami Aceh
Authors: Regina Fransiska Maria , Roosandriantini Josephine
Published: December 2024

Regionalisme memiliki 2 macam yaitu Vernakularisme yang bentukannya dibatasi skala dan fungsi dan terdapat juga regionalisme modern yang penekannya pada bentuk dan materialnya. Critical regionalism masih tetap meneruskan tradisi seperti yang ada pada regionalism tetapi lebih banyak mengikuti unsur modernisasi. Glenn Murcutt memiliki teori yang sesuai dengan critical regionalism yaitu terdapat identitas serta kearifan lokal, selain itu juga kontekstual, dengan sustainable architecture, serta high tech culture yang turut berperan, dan desain bangunan haruslah ramah lingkungan. Rumusan masalah tentang bagaimana penerapan yangcritical regionalism pada bangunan Marika Alderton Housed dan Museum Tsunami Aceh. Dengan metode penelitian deskriptif kualitatif melaluli tinjauan literature. Penerapan critical regionalisme adalah pada bangunan Marika Alderton House di Australia yang mengambil nilai tradisional masyarakat Aborigin dan material prefebrikasi ramah lingkungan. Bangunan yang kedua adalah penerapan pada Museum Tsunami Aceh yang ada di Indonesia dengan tema Escape Hill sebagai kenangan atas peristiwa Tsunami Aceh. Kearifan local yang diambil adalah konsep rumah tradisional yang berupa panggung dan tarian saman sebagai secondary skin. saran yang penulis ajukan ialah hendaknya penelitian selanjutnya memperdalam  dan mengembangkan ruang lingkup tentang penerapan teori critical regionalism agar menjadi optimal dalam mendapatkan data yang diperlukan.
Risks of anti-Helicobacter therapy and long-term therapy with antisecretory drugs
Authors: Kotelevets Sergey M
Published: December 2024

Helicobacter pylori (H. pylori ) infection has a protective effect on gastroesophageal reflux disease (GERD). Both of these diseases have a very high incidence and prevalence. As a result, GERD often recurs after anti-Helicobacter therapy. The problem of effective treatment of H. pylori infection and GERD is that the main groups of drugs [proton pump inhibitors (PPIs) and potassium-competitive acid blockers] have the possibility of side effects with use. Such supposed side effects have no evidence in randomized controlled trials that comply with the principles of evidence-based medicine. Morphological changes in the gastric mucosa after long-term use of antisecretory drugs should be considered as compensatory mechanisms of sanogenesis. The greatest concern for doctors who treat patients with antisecretory drugs is the risk of gastric carcinogenesis. This article presents an analysis of morphological and pathophysiological changes that occur after long-term use of antisecretory drugs (PPIs). Hypertrophy (hyperplasia) of G cells, enterochromaffin-like cells and possible fundic gland polyps (hyperplasia) are compensatory mechanisms of sanogenesis during long-term treatment with PPIs. These mechanisms are of primary importance for rehabilitation and prevention of complications in patients with GERD, non-steroidal anti-inflammatory drugs-gastropathy and other diseases during long-term treatment with PPIs. Understanding the pathophysiological and morphological mechanisms of compensation and adaptation, the mechanisms of sanogenesis and carcinogenesis will increase the number of indications for long-term use of PPIs with a high level of efficiency and safety of treatment. In addition, understanding the pathophysiological and morphological mechanisms of compensation and adaptation, the mechanisms of sanogenesis will allow us to forecast the side effects of long-term use of potassium-competitive acid blockers.
Exploring the links between gallstone disease, non-alcoholic fatty liver disease, and kidney stones: A path to comprehensive prevention
Authors: Demarquoy Jean
Published: December 2024

The recent study exploring the bidirectional associations between gallstone disease, non-alcoholic fatty liver disease, and kidney stone disease highlights a critical concern in chronic disease management. Given the rising global prevalence of these conditions, understanding their interconnections is essential. The study emphasizes the importance of shared risk factors, such as obesity, type 2 diabetes, dyslipidemia, and oxidative stress, and calls for multidisciplinary screening strategies. This approach would improve patient outcomes and reduce the socio-economic burden. While the study contributes valuable insights from a Chinese population, further research across diverse populations is necessary to validate and extend these findings globally. Ultimately, the research underscores the need for integrated prevention programs to better manage these interconnected diseases and improve health outcomes.
Effect of Modulen vs budesonide on clinical response and mucosal healing in Crohn’s patients
Authors: Ovadia Baruch , Niv Eva , Stern Katie Sara , Mahajna Elisabeth , Gal Oren , Kopelman Yael
Published: December 2024

BACKGROUND

Mucosal healing has become an important goal of Crohn’s disease (CD) treatments. Modulen, enriched with transforming growth factor-beta 2, and budesonide are commonly accepted treatments for mild-moderate CD. However, their effects on the small bowel (SB) mucosa remain underexplored.

AIM

To prospectively assess clinical and mucosal responses to Modulen vs budesonide in adults with CD, using SB capsule endoscopy.

METHODS

Thirty patients were divided into two groups: Modulen + home-based diet (21 patients) and budesonide (9 patients) for an eight-week intervention followed by four weeks of follow-up. Clinical, laboratory, and endoscopic responses were evaluated. The mucosal changes were assessed through SB capsule endoscopy.

RESULTS

Results indicated significant clinical improvement in the Modulen group with reduced CD activity index (P = 0.041) and improved inflammatory bowel disease questionnaire score (P = 0.016). Moreover, Modulen was associated with a significant SB mucosal improvement, evidenced by a decrease in Lewis score (P = 0.027). No significant changes were observed in calprotectin or other laboratory parameters. Conversely, budesonide exhibited more modest clinical effects, but it improved calprotectin, hemoglobin, and C-reactive protein levels (P = 0.051, P = 0.014, and P = 0.038, respectively). The capsule endoscopy did not reveal a significant mucosal response in the budesonide group.

CONCLUSION

Both interventions have a role in CD treatment. Yet, their effects differ and may complement each other: Modulen yields clinical and mucosal improvements, while budesonide primarily leads mainly to laboratory improvements.
Impact of triglyceride-glucose index on the long-term prognosis of advanced gastric cancer patients receiving immunotherapy combined with chemotherapy
Authors: Yao Zhi-Yuan , Ma Xiao , Cui Yong-Zheng , Liu Jie , Han Zheng-Xiang , Song Jun
Published: December 2024

BACKGROUND

Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of death worldwide. Despite advancements in immunotherapies, patient prognosis remains poor, necessitating the identification of key prognostic factors to optimize the treatment approaches. Insulin resistance, as indicated by the triglyceride glucose (TyG) index, is increasingly recognized for its impact on cancer progression and immune modulation, and its potential role in GC prognosis is of particular interest.

AIM

To investigate whether the TyG index, a surrogate marker of insulin resistance, can predict the prognosis of patients with advanced GC receiving immunotherapy combined with chemotherapy.

METHODS

This retrospective study included 300 patients with advanced GC who received sintilimab combined with chemotherapy. The patients were categorized into two groups according to high or low TyG index, and independent prognostic factors for overall survival (OS) were determined using Cox proportional hazards regression analysis, which led to the development of a nomogram model.

RESULTS

Of the included patients, 136 had a high TyG index and 164 had a low TyG index. The median progression-free survival of the high TyG index group was significantly longer than that of the low TyG index group. Similarly, the median OS of the high TyG index group was significantly longer than that of the low TyG index group. The objective response and disease control rates in the two groups were 18.38% vs 9.15% and 58.82% vs 46.95%, respectively. No significant difference was noted in the incidence of adverse reactions at any level between the two groups (P > 0.05). In multivariate analysis, the Eastern Cooperative Oncology Group score, programmed cell death ligand 1 expression, and TyG index acted as independent prognostic factors for OS. Of these factors, the hazard ratio of the TyG index was 0.36 (95% confidence interval: 0.36-0.55, P < 0.001), and the nomogram model re-emphasized its importance as the main predictor of patient prognosis, followed by programmed cell death ligand 1 expression and the Eastern Cooperative Oncology Group score.

CONCLUSION

The TyG index is a long-term predictor of the efficacy of immunotherapy combined with chemotherapy, and patients with a high index have a better prognosis.
Risk factors, prevention and screening of colorectal cancer: A rising problem
Authors: Tsukanov Vladislav V , Vasyutin Alexander V , Tonkikh Julia L
Published: December 2024

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer death worldwide. The leading risk factors for CRC include male gender, age over 50, family history, obesity, tobacco smoking, alcohol consumption, and unhealthy diet. CRC screening methods vary considerably between countries and depend on incidence, economic resources and healthcare structure. Important aspects of screening include adherence, which can vary significantly across ethnic and socioeconomic groups. Basic concepts of CRC screening include pre-stratification of patients by identifying risk factors and then using fecal immunochemical test or guaiac-based fecal occult blood test and/or colonoscopy or radiologic imaging techniques. Technological capabilities for CRC screening are rapidly evolving and include stool DNA test, liquid biopsy, virtual colonography, and the use of artificial intelligence. A CRC prevention strategy should be comprehensive and include active patient education along with targeted implementation of screening.
The first record of Agoo Bahder & Bartlett, 2019 (Hemiptera: Fulgoroidea: Derbidae) for the state of Amazonas, Brazil, with the description of a new species
Authors: Cantanhede Inezita , Viegas Eduarda F. G. , Ale-Rocha Rosaly
Published: December 2024

For the first time, the occurrence of the genus Agoo Bahder & Bartlett, 2019 (Hemiptera: Fulgoroidea: Derbidae) was recorded in the state of Amazonas, Brazil, through the discovery of a new species for the genus. Additionally, we describe and illustrate Agoo galbina sp. nov. and present a geographic distribution map of Brazilian species based on literature data.
Measuring visual ability in linguistically diverse populations
Authors: Hooper Madison A. , Tomarken Andrew , Gauthier Isabel
Published: December 2024

Measurement of object recognition (OR) ability could predict learning and success in real-world settings, and there is hope that it may reduce bias often observed in cognitive tests. Although the measurement of visual OR is not expected to be influenced by the language of participants or the language of instructions, these assumptions remain largely untested. Here, we address the challenges of measuring OR abilities across linguistically diverse populations. In Study 1, we find that English–Spanish bilinguals, when randomly assigned to the English or Spanish version of the novel object memory test (NOMT), exhibit a highly similar overall performance. Study 2 extends this by assessing psychometric equivalence using an approach grounded in item response theory (IRT). We examined whether groups fluent in English or Spanish differed in (a) latent OR ability as assessed by a three-parameter logistic IRT model, and (2) the mapping of observed item responses on the latent OR construct, as assessed by differential item functioning (DIF) analyses. Spanish speakers performed better than English speakers, a difference we suggest is due to motivational differences between groups of vastly different size on the Prolific platform. That we found no substantial DIF between the groups tested in English or Spanish on the NOMT indicates measurement invariance. The feasibility of increasing diversity by combining groups tested in different languages remains unexplored. Adopting this approach could enable visual scientists to enhance diversity, equity, and inclusion in their research, and potentially in the broader application of their work in society.
Mechanistic insights into endosomal escape by sodium oleate-modified liposomes
Authors: Sadaqa Ebrahim , Satrialdi  , Kurniawan Fransiska , Mudhakir Diky
Published: December 2024

Endosomal entrapment significantly limits the efficacy of drug delivery systems. This study investigates sodium oleate-modified liposomes (SO-Lipo) as an innovative strategy to enhance endosomal escape and improve cytosolic delivery in 4T1 triple-negative breast cancer cells. We aimed to elucidate the mechanistic role of sodium oleate in promoting endosomal escape and compared the performance of SO-Lipo with unmodified liposomes (Unmodified-Lipo) and Aurein 1.2-modified liposomes (AUR-Lipo). Liposomes were prepared using the thin-film hydration method, resulting in Unmodified-Lipo, SO-Lipo, and AUR-Lipo formulations. The particle sizes were 102.2 ± 3.30 nm for Unmodified-Lipo, 109.6 ± 7.65 nm for SO-Lipo, and 151.9 ± 5.88 nm for AUR-Lipo, with polydispersity indices below 0.25, indicating uniform size distribution. Endosomal escape efficiency was evaluated through confocal microscopy by measuring the colocalization of labeled liposomes with lysosomal markers, quantified using Pearson’s correlation coefficient. Lipid mixing assays assessed the potential fusogenic effect, and molecular dynamics (MD) simulations explored the interactions of protonated sodium oleate (SO) with the endosomal membrane. Results demonstrated that SO-Lipo exhibited superior endosomal escape compared to Unmodified-Lipo, as evidenced by reduced colocalization with lysosomal markers, and achieved comparable efficacy to AUR-Lipo with lower cytotoxicity. Lipid mixing assays confirmed the potential fusogenic effect of SO with endosomal membrane models. MD simulations revealed that under acidic endosomal conditions, SO is protonated to oleic acid, which integrates into the membrane, enhancing fluidity and promoting fusion events essential for cytosolic release. SO-Lipo enhance endosomal escape through a fusogenic mechanism, facilitating cytosolic delivery with reduced cytotoxicity. This approach offers a safer and more effective option for targeted drug delivery applications.
Studying Some of the Consequence of Workplace Ostracism, Bullying, Cyber-bullying at the University Context
Authors: Omran Sally Kamel Ali
Published: December 2024

The presence of stressful, adverse workplace behaviors is one of the key issues that dominate many organizations nowadays. Deviant work behaviors with its different forms and types is considered one of the vital areas that need to be addressed due to its sever implications. Thus, this research focused on studying some of the consequences of three deviant behaviors (workplace ostracism, bullying and cyber-bulling). For testing the proposed model and the developed hypotheses, this research is based on a collected data from a proportional stratified random sample of 384 undergraduate students at Cairo University in Egypt. The obtained results from the analyzed data indicated that: (1) workplace ostracism , Workplace bullying and cyber-bullying are negatively, strongly and significantly related with : students' academic achievement level, their self-esteem level, and with their affective commitment level for their colleges.(2)workplace ostracism, bullying and cyber-bullying operating jointly and explain 25.1% of the academic achievement, 25.3% of self-esteem and 26% of the affective commitment.