bluuebunny/crossref_metadata_2025 huggingface dataset:
In vivo selection of the MDA-MB-231br/eGFP cancer cell line to obtain a clinically relevant rat model for triple negative breast cancer brain metastasis
Authors: De Meulenaere Valerie , Descamps Benedicte , De Wever Olivier , Vanhove Christian , Deblaere Karel
Published: December 2020

Young triple negative breast cancer (TNBC) patients are at high risk for developing very aggressive brain metastases associated with a poor prognosis and a high mortality rate. Preclinical models that allow follow-up by magnetic resonance imaging (MRI) can contribute to the development of new therapeutic approaches for brain metastasis. To date, preclinical brain tumor research has almost exclusively relied on xenograft mouse models. Yet, rats are an ideal model for imaging of brain metastasis as their larger brain offers better relative spatial resolution compared to a mouse brain. For the development of a clinically relevant rat model for TNBC brain metastasis, the MDA-MB-231br/eGFP cancer cell line can be used. However, as a result of species-dependent extracranial features, the propensity of the MDA-MB-231br/eGFP cancer cell line to metastasize exclusively to the brain needs to be enhanced by in vivo selection. In this study, repeated sequential passages of metastatic cancer cells obtained from brain metastases in nude rats were performed. Brain metastasis formation was evaluated using preclinical MRI, while bone metastasis formation was assessed using high-resolution computed tomography (CT) and 2-deoxy-2-[18F] fluoro-D-glucose ([18F] FDG) positron emission tomography (PET) imaging. Our results demonstrated that the metastatic tumor burden in the rat brain (number and volume) significantly increased with increasing passage, while the metastatic tumor burden in the skeleton (i.e., number of metastasis-affected bones) significantly decreased with increasing passage. However, bone metastasis development was not reduced to a negligible amount. Consequently, despite in vivo selection, our rat model is not recommended for investigating brain metastasis as a single disease. Our findings highlight the importance of well-reasoned selection of both the preclinical model and the cancer cell line in order to obtain reliable and reproducible scientific results.
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein
Authors: Dinesh Dhurvas Chandrasekaran , Chalupska Dominika , Silhan Jan , Koutna Eliska , Nencka Radim , Veverka Vaclav , Boura Evzen
Published: December 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is a single-stranded positive-sense RNA virus. Like other coronaviruses, SARS-CoV-2 has an unusually large genome that encodes four structural proteins and sixteen nonstructural proteins. The structural nucleocapsid phosphoprotein N is essential for linking the viral genome to the viral membrane. Both N-terminal RNA binding (N-NTD) and C-terminal dimerization domains are involved in capturing the RNA genome and, the intrinsically disordered region between these domains anchors the ribonucleoprotein complex to the viral membrane. Here, we characterized the structure of the N-NTD and its interaction with RNA using NMR spectroscopy. We observed a positively charged canyon on the surface of the N-NTD that might serve as a putative RNA binding site similarly to other coronaviruses. The subsequent NMR titrations using single-stranded and double-stranded RNA revealed a much more extensive U-shaped RNA-binding cleft lined with regularly distributed arginines and lysines. The NMR data supported by mutational analysis allowed us to construct hybrid atomic models of the N-NTD/RNA complex that provided detailed insight into RNA recognition.
The meaning(s) of practice: Puzzling through performative language practice with refugee learners
Authors: Piazzoli Erika , Cullen Elif Kir
Published: December 2020

This article features an investigation into the semantics of the term ‘practice’ coexisting in a multidisciplinary research context. The background of the discussion is a government-funded study with refugees and asylum seekers in Ireland, where process drama, music and dance were used to facilitate second language learning – an approach known as performative language pedagogy. The research is framed by exploratory practice, a methodology that considers ‘practice-as-research’ and ‘understanding-for-practice’ in second language education. An investigation of the meaning(s) of the term ‘practice’ was imperative as a semantic gap existed between the use of the term ‘practice’ in exploratory practice (the research methodology underpinning the study) and the concept of ‘practice’ in performative language pedagogy (the teaching approach used in the study). This article presents findings from twelve qualitative interviews with teacher/artists and practitioners that point towards a shared understanding of practice when working with refugees in language education settings.
Humanity in a time of collective initiation
Authors: Hartley Linda
Published: December 2020

As our whole global community entered a period of much loss, both personal and collective, the realization came to me that we are facing a process of collective initiation. Initiation always involves a loss of some sort and, to some degree, a potential for something new to be born. Initiatory journeys, which have been mapped by shamans since antiquity, and in the myths and legends of various cultures, show us an archetypal pattern of loss and death, dismemberment or burning, followed by renewal and rebirth. We also each know this process, however unconsciously, in our own embodied experience of birth, where the same archetypal pattern can be discerned. In this article I will explore the connection between the birth process, mapped in Grof’s Basic Perinatal Matrix, and the collective crisis of illness, intense pressure and restriction, loss and death that we are currently facing. Having such a map to contextualize the intensity of experience we are going through is a resource that helps me to be with all that is happening and changing in our world.
Dokimasies: Opseis tou oikogeneiakou plegmatos sto neoelliniko Mythistorima 1922–1974 (‘Ordeals: Aspects of family entanglements in the modern Greek novel 1922–1974’), Mairi Mike (2019)
Authors: Akritidou Maria
Published: December 2020

Review of: Dokimasies: Opseis tou oikogeneiakou plegmatos sto neoelliniko Mythistorima 1922–1974 (‘Ordeals: Aspects of family entanglements in the modern Greek novel 1922–1974’), Mairi Mike (2019)

Athens: Gutenberg, 486 pp.,

ISBN 978-960-01-2034-9, h/bk, €26.00
‘This sperm hits the bullseye’: Bollywood, youth and male (im)potency as a neoliberal game
Authors: Chakrabarti Baidurya
Published: December 2020

This article, by closely examining the trajectory of the upcoming Bollywood star Ayushmann Khurrana, tries to unravel the constitutive fantasies that provide a significant degree of coherence to his star-image. Through a close textual reading, the article aligns these fantasies with the diurnal realities of neoliberal India. In these fantasies, the male protagonist is found to be (a) the privileged embodiment of a surplus/lack that comes to signify the ‘thing’ called the modern, but (b) the man and his sociality is not prepared yet to accept this ‘thing’, thus triggering comedy; it is only in romantic conjugation with (c) a working woman can this excess charge of the modern be resolved within the narratives. Using psychoanalytic insights, the article unpacks these fantasies as ones involving both a crisis and an ultimately infantile reaction to it.
Coaching centre as camp: Structures of feeling in popular representations of India’s coaching industry
Authors: Salovaara Isabel M.
Published: December 2020

In the last two decades, critical representations of the Indian education system have gained prominence in Hindi-language popular media. Centring on concerns about both pedagogy and inequality, these media texts have recently begun to incorporate fictionalized depictions of schooling beyond school – the vast ‘shadow education’ system that prepares students for school tests and competitive examinations in engineering, medical, civil service and other primarily technical and professional fields. This article explores the political significance of ambivalences that inhere within and between representations of the coaching industry. These ambivalences produce a narrative of enclosure in which upper-caste middle classes endure persecution while simultaneously engaging in forms of disciplinary self-fashioning in service to the nation. These ‘structures of feeling’ resonate with social theories of the camp, reconsidered from the Indian context.
Lost spectacle: Media consumption by Kashmiri youth in the absence of cinema halls
Authors: Farooq Gowhar
Published: December 2020

Hardline militants forced the cinema halls in Kashmir into closure in 1989. As heavy militarization ensued, several spaces, including cinema halls, were transformed into structures where people, especially young men, were detained and tortured by soldiers and militia. The generations born after the 1980s, therefore, grew up in a cinema-less, militarized world. In the absence of functional cinema halls, they, for years, relied on the state broadcaster for movies and media. Later – although under tremendous threat from extremists – a network of local cable TV operators, who functioned without licences, provided some succour. They were followed by pirate video-cassette and compact-disk parlours that provided people with a means to stay connected to movie culture. And, while the scene changed with the arrival of satellite TV, computers and later the internet, which connected the youth of the region to the larger global media culture, the absence of cinema persists. This article aims to explore how youth, born after the 1980s, associate with cinema halls of Kashmir and what the loss of the cinema viewing culture means to them. To this end, I intend to look into cinema culture before the 1990s and the politics around the closure of cinema halls. The article will also put into perspective the arrival of satellite TV and the circulation of pirated video cassettes, compact disks and videos of the funerals of rebels that were filmed and circulated by rental shops. These practices and processes, which shaped the childhood and youth of several generations in Kashmir, offer insights into the media consumption and the role the state and its apparatuses have in shaping the youth in a conflict-ridden and militarized region of the Global South.
Academic literacies of international students in New Zealand library environments
Authors: Gopi Suhasini , Tran Ly Thi , Hutchison Kirsten
Published: December 2020

This article is based on a study that explores international students’ understanding of academic literacies in New Zealand library environments. The article aims to provide insights into international higher degree students’ (IHDSs’) understandings of their academic literacy practices in library environments. To address this issue, the study utilizes an interpretative framework drawing from Vygotsky’s sociocultural theory. Despite a significant body of literature on international students, little is known about the interaction of this cohort with the academic library, and limited information is available on IHDSs’ academic literacies in New Zealand library environments. Our article responds to this critical gap in the existing literature on international students. The findings of the study underscore the importance for librarians, learning advisors and academics to consider international students’ characteristics, language proficiency, learning styles and interests in designing teaching techniques and effective support for this cohort.
Study-work-life balance: Challenges for international students
Authors: Mahler Martin Lukas
Published: December 2020

The purpose of this article is to explore to what extent international students may be affected by a lack of study/work-life balance or study-work-life balance amongst those who study (full-time) and work part-time. International students tend to face more pressures due to usually lacking a support network, at least for some time once arriving in the host country. Such pressures may be financial or social and may be due to a lack of awareness of host country norms and regulations or due to language barriers. An online survey informed by work-life balance theory was completed by 42 international students. The findings from the analysis of responses were that while most respondents were satisfied with their study-work-life balance, some although managing overall, faced pressures. A key finding was that the students managed due to the student visa condition restricting employment to a maximum of twenty hours per week. This seems to have helped respondents to focus more time on their studies, however, may add to financial pressures or put international students at a disadvantage over their domestic peers in terms of gaining work experience. Further, findings have uncovered that although working while studying provides additional pressures, it creates benefits through the ability to build a support network.
Examination of a New Zealand tertiary guide for teaching international students
Authors: Vail Heather
Published: December 2020

This article examines the impetus for and development of a guide for teaching international students at a polytechnic in New Zealand. Tensions educators may experience when teaching and assessing international students have sometimes been overlooked due to a primary focus on the sector’s economic value. The authors are educators who acknowledge the strengthening of global education as it trends around the world and the emerging initiatives New Zealand has put in place to remain relevant. In the Guide, we focus on the educators’ realm, the classroom, and offer research informed strategies for teachers to better facilitate successful learning outcomes. The Guide discussed is an in-house publication.
INVOLVEMENT OF THE POPULATION IN SOLVING LOCAL ISSUES: HISTORIOGRAPHY AND THE EXPERIENCE OF THE ALTAI TERRITORY
Authors: Boev Nikita Vadimovich , Trotskovsky Alexander Yakovlevich
Published: December 2020

The article defines initiative budgeting — the Russian version of the participatory budgeting method widely known abroad, which appeared in the late 1980s in Porto Alegre (Brazil). The emergence of participatory budgeting was a response to the need for citizens and government representatives to work together in solving urban problems. The successful experience of Porto Alegre first began to be replicated in Brazil, and then in other Latin American countries. As a result, participatory budgeting began to spread around the world. In Russia, the most common practice of initiative budgeting was the program for supporting local initiatives, which was launched in the Stavropol territory, demonstrating the possibility of actually involving citizens in solving local issues and improving the quality of the dialogue between the government and the population, increasing citizens «satisfaction with local government procedures and trust in them. The paper presents the experience of participation of the Altai territory in the practice of initiative budgeting, which is considered by the authors in the context of modern concepts of regional research and formation of strategies for territorial development.
THE ROLE OF THE EUROPEAN AGRICULTURAL FUNDING IN BULGARIA
Authors: Stoichkova Ognyan
Published: December 2020

The article deals with the issues related to financing of agricultural industry in Bulgaria from the EU funds and programs. The outcomes of European support under the first and second pillars of the Common Agricultural Policy of the European Union, in which Bulgaria has been participating since 2007, are analyzed. Besides, the positive effects on Bulgaria’s agriculture as well as the problems facing the agricultural sector in the new programming period are highlighted.
A vállalati társadalmi felelősségvállalás kommunikációjának elvei és eszközrendszere a marketingben
Authors: Lukács Rita
Published: December 2020

A vállalatok társadalmi felelősségvállalása egyre jobban érdekli az érintetteket, akik a vállalat CSR teljesítményével kapcsolatos információk megszerzése mellett nagyobb rálátást akarnak nyerni a vállalat tevékenységére és terveire, ráadásul részt is akarnak venni ezek kialakításában. A fokozódó elvárások paradigmaváltást igényelnek a vállalatok kommunikációs tevékenységében is, az egyirányú helyett kétirányú, illetve hálózati alapú kommunikációs stratégiákat, valamint új és újragondolt kommunikációs eszközöket. A cikk bemutatja a témával kapcsolatos főbb elveket és elméleteket, illetve a CSR-kommunikáció eszköztárát és az érintettek bevonása révén elérhető előnyöket.
Parto humanizado e interdisciplinaridade: um olhar sobre a saúde da mulher e da criança a partir da experiência de trabalho do Hospital Sofia Feldman
Authors: Cotta Fernanda Mitre , Amaral Ana Paula da Silva , Chaves Priscila Gonçalves Resende
Published: December 2020

Segundo a Organização Mundial de Saúde (OMS), o Brasil é o país campeão de cirurgias cesarianas no mundo – 82% na rede particular e 37% na pública; mais que o dobro do recomendado que é de 15%. Além dos riscos da cirurgia, estas acabam impedindo medidas que fazem bem para o binômio mãe-bebê, como amamentação na primeira hora e clampeamento tardio do cordão umbilical. Nesta linha, o Hospital Sofia Feldman (HSF), tem como objetivo, prestar atendimento pelo SUS, com qualidade, de forma interdisciplinar e humanizado. Apresentar os dados de atendimento do HSF, cuja missão é desenvolver ações de atenção integral à saúde da mulher e da criança, com qualidade e resolutividade, de forma universal, visando impactar nos indicadores de saúde deste grupo. Estudo de caso, com apresentação dos indicadores, segundo a série histórica dos anos de 2013, 2014 e 2015, respectivamente, elaborados de acordo com o item 5 do Termo de Compromisso das Maternidades do SUS-BH estabelecido pela Comissão Perinatal da Secretaria Municipal de Saúde de Belo Horizonte. O HSF assiste a uma população superior a 400 mil pessoas. O total de partos realizados nos anos de 2013, 2014 e 2015 foram de 11.020, 11.271 e 11.471 respectivamente; destes 24,7%, 24,9% e 24,0% foram cesáreas, destaca-se que apesar de ser superior ao recomendado pela OMS, o HSF atende a uma grande porcentagem de gestantes de alto risco e só indica partos cesário quando a gestante é iterativa ou quando há indicação materna ou fetal; quanto aos partos normais, 18,6%, 21,9% e 22% foram assistidos por médicos enquanto 81,4%, 78,1% e 78% por enfermeiros; referente a Episiotomia destaca-se que apenas foi realizado 5,8%, 3,6% e 3,1%; relativo a interação mãe/filho na sala de parto, ocorreu em 86,1%, 86,7% e 86.6% dos partos, a taxa de ocupação instalada na maternidade foi 98,1%, 100,5% e 96,7%, e a mortalidade materna foi de 3, 5 e 2, respectivamente. Na maternidade, a equipe multi e interdisciplinar oferece atenção humanizada, buscando favorecer os laços mãe, filho e família através de ações como: ênfase na imagem do parto normal como uma forma prazerosa, segura e saudável de dar à luz; o empoderamento e valorização da mulher pela conscientização de seus direitos; o envolvimento do homem-pai no processo de nascimento; a presença de um acompanhante da escolha da mulher durante o trabalho de parto; a valorização da atenção da(o) enfermeira(o) obstetra; a segurança e o apoio das Doulas; o incentivo a promoção do aleitamento materno; a valorização de uma rede de proteção social ao recém-nascido e a mãe e a internação conjunta para mães e filhos em alojamento conjunto.
Análise postural em estudantes de uma escola pública de Viçosa, Minas Gerais
Authors: Moreira Joelma Barbosa , De Freitas Léo Marques Soares , Soares Ana Carolina Lima , Faraci Lucas Lopes , Nascimento Matheus , Martinho Karina
Published: December 2020

Pesquisas apontam que várias complicações que possa interferir na postura surgem no período de maturação musculoesquelética, ou seja, na infância e adolescência, fase onde esses se encontram na escola, propiciando há adquirir maus hábitos que levam a alterar a sua postura. Avaliar as alterações posturais de escolares de uma escola pública de Viçosa-MG e relacionar com o uso correto da mochila e ocorrências de dor. Foi realizado um estudo estatístico descritivo do tipo transversal, em uma escola estadual de Viçosa – MG, composta por 36 alunos do 1º ano do ensino médio com faixa etária de 15 a 18 anos, de ambos os gêneros, 19 meninas e 17 meninos, porém desses, apenas 24 aceitaram tirar as fotos para analise postural. Também foram coletados dados biológicos (idade e sexo). Para avaliação postural utilizou-se uma câmera fotográfica digital Fujifilm – FinePix S8200 e o programa Fisimetrix.V.2,5i para analise das imagens. Foi aplicado um questionário elaborado e utilizado o programa Stata que por meio do teste qui-quadrado de person, verificaram-se as associações entre as variáveis qualitativas e por meio do teste T compararam-se as médias das variáveis quantitativas. Verificou-se que dos 24 alunos, 63,16% que têm dor é do sexo e 41,18% do sexo masculino. As alterações posturais encontradas foram: cabeça inclinada (33,11%), pescoço inclinado a esquerda (65%), ombro protuso (66,67%), hipercifose torácica (83,3%), lombar retificada (37,5%) e hiperlordose (37,5%). Quando relacionados com a dor, 65% apresentam inclinação à esquerda do pescoço e 68,75% ombro protuso, assim obtendo uma diferença significativa e, 46, 15% cabeça inclinada, 55% hipercifose torácica, 77,78% hiperlordose lombar. A maioria carrega a mochila bilateralmente (72.22%), e relacionando a dor, também apresentou uma diferença significativa. Observou-se que as alterações posturais estão relacionadas com o sexo, ocorrência de dor e a formar de carregar a mochila. A capacidade de generalização deste estudo torna-se limitada pelo tamanho da amostra e por não todos os estudantes terem aceitado tirar as fotos para analise postural, porém os resultados indicam a necessidade de realizações de ações preventivas e educacionais no ambiente escolar.
Análise dos casos de sífilis congênita no município de Manhuaçu – MG
Authors: Berbert-Morais Monick , Dutra-Costa Emanuele Gama , Santiago-Silva Juliana
Published: December 2020

A sífilis em mulheres grávidas causa, com frequência, a sífilis congênita, doença com grande repercussão para a família e para a sociedade. Esta é resultado da disseminação da bactéria T. pallidum da gestante infectada, não tratada ou tratada de forma desapropriada, para o bebê por via transplacentária. A doença permanece como um importante problema de saúde pública. No Brasil, estima-se que no ano de 2013 tenham ocorrido aproximadamente 21.382 casos de sífilis em gestantes, sendo 47% deles concentrados na região Sudeste. A cada ano mais casos de sífilis são registrados no município de Manhuaçu – MG. Em 2013 a taxa de detecção de sífilis em gestantes foi de 13,25%, um número bem alto se comparado com 2007, onde não houve nenhum caso registrado da doença. Analisar os casos de sífilis congênita no município de Manhuaçu – MG, relacionando com os dados socioeconômicos das gestantes e as consequências apresentadas pelos recém-nascidos. Trata-se do estudo qualiquantitativo, onde foram verificados os casos de gestantes infectadas pela bactéria Treponema pallidum e os casos de evolução para sífilis congênita, entre os anos de 2010 a 2015. Foram encontrados 84 casos de sífilis em gestantes, dos quais 46 evoluíram para sífilis congênita. A maioria das gestantes analisadas apresentou baixa escolaridade e apenas 15 tiveram os respectivos parceiros tratados. A faixa etária das gestantes também mostra que a maioria dos casos atinge adolescentes e jovens que, porventura não possuem emprego formal. Ainda existem casos onde a gestante é diagnosticada apenas no momento do parto. Com o aumento dos casos, nota-se que a assistência pré-natal deve ser renovada.
Residência Multiprofissional em Atenção Básica: a inserção de grupos na rotina de trabalhos de um PSF no Município de Petrópolis
Authors: De Azevedo Rafaella Araújo , Marcolino Mariana Leal , Mathias Desirré , Curioni Raphael
Published: December 2020

As atividades dos Postos de Saúde da Família (PSF) influenciadas por um viés biomédico se transformaram em algo distante da estratégia de cuidado, prevenção e promoção de saúde de forma coletiva e comunitária proposta na Atenção Básica (AB) dentro da perspectiva de territorialização. Desenvolver estratégias que deem vazão em um sentido coletivo e não a um olhar individualizante (quase ambulatorial) ou em práticas verticalizadas contempla a visão de forma de trabalho na AB. As iniciativas norteadas pelos residentes do programa de residência multiprofissional da FASE/FMP inseridos no PSF Fazenda Inglesa no município de Petrópolis-RJ buscam romper com a atual conjuntura e retomar o foco dessa unidade dentro de ações coletivas através da implementação de grupos dentro do posto de saúde. Em 2016 os profissionais residentes (equipe composta por enfermeiro, nutricionista e psicólogo) iniciaram esse processo através da transformação de um já existente e grupo, o “Qualidade de Vida”, no “Grupo das Mulheres”. Em um segundo momento houve a inserção do “Grupo dos Homens. Para que os grupos tivessem início e conseguissem se consolidar foi preciso um árduo trabalho de convencimento com os agentes comunitários para compreensão das magnitudes de um trabalho não restrito ao atendimento individual. A equipe técnica e administrativa do PSF se colocou desde o início de forma cooperativa, fazendo convites para os usuários irem aos grupos. A sala de espera também foi outra estratégia criada, sendo comunicada a possibilidade de participação de grupos enquanto esperavam atendimento. Os grupos das mulheres e dos homens (operativos) possuem duas regras de participação: enquadrarem-se no gênero e maiores de 19 anos, sem a obrigatoriedade de continuidade; são realizados semanalmente, com duração de uma hora e meia, e possuem objetivos específicos de acordo com o público atendido. Através dessa proposta é possível envolver os membros da equipe, tanto agentes comunitários como o quadro técnico, fazendo com que essa experiência possa consolidar essas atividades como fixas no posto ou que outras possam ser feitas. Outro aspecto importante é a condução do trabalho no viés de promoção e acompanhamento da saúde do território de forma a levar em conta o traçado histórico e coletivo da região adstrita pelo PSF, ou seja, dentro de uma lógica promotora em âmbito comunitário e coletivo. Esse estudo encontra-se em viés de andamento e teve seu início no mês de abril de 2016 e se espera que esse tipo de abordagem atue de forma preventiva e promotora à saúde com um cuidado acompanhado em um viés coletivo para o cuidado da saúde física e saúde mental do usuário daquele local, além da construção de outros tipos de grupo.
Eficácia da gastronomia na aceitabilidade da alimentação escolar
Authors: Santos Virgínia Souza , Da Silva Diana Elen , Abranches Monise Viana , Nardelli Giovanna Gaudenci , Gaudenci Eliana Maria , Pedrosa Leila Aparecida Kauchakje
Published: December 2020

O uso de técnicas gastronômicas pode ser uma alternativa eficaz para a melhoria da aceitação da alimentação escolar, especialmente na fase pré-escolar, quando as crianças sentem a necessidade de tocar a comida, sentir as formas, texturas e aromas, além de poderem descobrir as diferentes cores dos alimentos. Avaliar a aceitação da alimentação escolar antes e após o emprego de técnicas gastronômicas, por crianças em idade pré-escolar. Participaram da pesquisa 26 crianças, com idade mediana de 5,4 anos (5,0 - 5,9), sendo 53,8% (n=14) do sexo feminino, cujos pais autorizaram a participação mediante a assinatura do Termo de Consentimento Livre e Esclarecido. Para avaliação da aceitabilidade da alimentação escolar, foi aplicado um teste afetivo, empregando-se a escala hedônica facial de 5 pontos, durante 5 dias consecutivos e no mesmo horário, conforme proposto pelo Centro Colaborador de Alimentação e Nutrição Escolar – CECANE (2010). As refeições que apresentaram o Índice de Aceitabilidade (I.A.) ≥ 85% (percentual referente ao somatório das notas 4 e 5 atribuídas pelos alunos no teste afetivo) foram consideradas aceitas. Na fase seguinte, com a mesma duração, foram executadas modificações na alimentação escolar, empregando técnicas gastronômicas que permitissem uma melhor apresentação dos pratos servidos as crianças, por meio da utilização de aros de formatação de alimentos para enfeitar os pratos e o uso de condimentos para dar coloração e decorar os alimentos. Novamente foi realizada a analise sensorial das refeições distribuídas. Para a análise dos dados foi utilizado software Statistic Package for the Social Sciences - SPSS, versão 20.0 e empregou-se o teste Wilcoxon para comparação da média da pontuação atribuída pelos voluntários antes e após a aplicação das técnicas gastronômicas. O estudo foi aprovado pelo Comitê de Ética em Pesquisa da Universidade Federal de Viçosa (protocolo no 773.222). De acordo com a análise sensorial, observou-se que a pontuação atribuída as refeições aumentou após o emprego da gastronomia, durante todos os dias. Foi observada diferença estatística apenas nas quartas-feiras ao comparar as notas atribuída antes e depois da aplicação das técnicas gastronômicas. Após a intervenção, houve aumento do índice de aceitação e todas as refeições passaram a ser aceitas (I.A. > 85,0%). As notas atribuídas pelos estudantes, mediante a aplicação do teste de aceitabilidade, aumentaram após o emprego de técnicas gastronômicas, o que permite inferir que essa estratégia possibilitou a melhoria da aceitabilidade da alimentação escolar.
A atuação da Univille no PET-Saúde/GraduaSUS
Authors: Magri Patricia Esther Fendrich , Paiano Helena Maria Antunes , Salin Mauren da Silva
Published: December 2020

O PET- Saúde/GraduaSUS é um programa federal que propõe a aproximação dos cursos da área da saúde com o SUS para reorientação da formação profissional em serviço. Em 2015, os cursos de Educação Física, Odontologia, Farmácia, Psicologia, Enfermagem e Medicina da Univille em parceria com a Secretaria de Saúde/Joinville-SC, elaboraram e conquistaram  a aprovação do projeto, cuja meta é implantar um componente curricular comum aos seis cursos. Objetivo: descrever as ações realizadas no Projeto PET-Saúde/GraduaSUS. Metodologia: Desde a aprovação, uma equipe de professores e profissionais da Secretaria de Saúde trabalham arduamente desenvolvendo uma proposta de implementação de um componente curricular que compreenda a atenção à saúde como uma prática interprofissional. As ações desenvolvidas para alcançar a meta se referem a estudos teóricos para definição de concepções de formação e trabalho interprofissional,  práticas  colaborativas e clínica ampliada; reuniões com os coordenadores de cursos, tanto quanto uma prática considerada piloto, na qual estudantes de graduação, profissionais de saúde e professores da universidade experimentam a ideia principal da proposta que é estar nas Unidades Básicas de Saúde (UBS), em grupos, experimentando a educação interprofissional em benefício da formação para atuar na promoção da saúde dos usuários do SUS. O principal resultado é a implantação do componente obrigatório Práticas Interprofissionais em Saúde a partir de 2018 nos cursos de Educação Física e Odontologia. Os estudantes irão compor turmas mistas com atividades na universidade, nas UBS e realizarão diagnóstico da realidade, planejamento e intervenções sob a supervisão de professores e preceptores. Conclusão: Embora se reconheça que o trabalho em equipe exige persistência e vontade de inovar, a meta do projeto está em processo de consolidação. Durante a caminhada muitos obstáculos tiveram que ser transpostos, porém com determinação, foco e liderança o componente está consolidado e no próximo ano poderemos relatar os resultados do componente.
As contribuições do trabalho interprofissional no contexto dos serviços de saúde ofertados em uma Unidade de Saúde do município de Benevides no estado do Pará
Authors: Vieira Alessandra dos Santos Tavares , Gomes Nayane Adrielle de Arruda , Silva Samara de Brito , Holanda Michelle Castro da Silva , Nascimento Liliane Silva do
Published: December 2020

Introdução: O Sistema Único de Saúde (SUS) preconiza uma atenção à saúde considerando o contexto e todos os níveis de atenção para promoção, proteção e recuperação, priorizando o caráter preventivo. Em virtude das transformações no cenário de saúde no Brasil, houve uma reorganização das ações de saúde na atenção básica, inserindo ações de saúde bucal a equipe. Sendo assim os profissionais não devem apenas contribuir para que os usuários adquiram conhecimentos sobre a saúde, mas sim da influência dos cuidados com a mesma sobre a saúde de forma integral. Objetivos: Relatar a experiência da ação educativa interdisciplinar sobre saúde bucal com as crianças e seus familiares usuários da unidade de saúde da família no bairro Santos Dumont, Benevides-PA. Métodos: Trata-se de um relato de experiência vivenciado pela equipe que compõe a unidade de saúde. Esta ação foi pensada em virtude de no acolhimento da demanda assistida uma elevada quantidade de crianças em necessidade de assistência odontológica percebida durante os atendimentos clínicos. Sendo denominada “Venha aprender a cuidar dos primeiros dentinhos”. Participaram da atividade além dos profissionais da unidade (auxiliares administrativos, técnico de enfermagem e agentes comunitários de saúde) 26 pessoas, entre crianças e familiares das mesmas. Resultados: Possibilitou o desenvolvimento da prática a partir da interprofissionalidade, com atividades de educação em saúde bucal com as crianças e seus familiares usuários da unidade de saúde, a qual percebeu-se a importância e o impacto que essa conversa educativa proporciona. Haja vista que houve interação de todos durante toda a ação, as crianças e seus responsáveis, além dos próprios profissionais da unidade. Conclusões: É gratificante perceber o trabalho interprofissional determina metodologias motivantes, tornando-se mais proveitoso, pois favorece a criação de vínculo, fortalece a corresponsabilidade e valoriza o autocuidado em saúde de forma integral.
Struktur kepemilikan saham terhadap profitabilitas dan nilai pada perusahaan perbankan
Authors: Surayya Surayya , Kadang Juliana
Published: December 2020

This study aims to determine the effect of managerial and public ownership structures on profitability at the Foreign Exchange National Private Commercial Banks (BUSN), determine the effect of managerial and public ownership structures on firm value at Foreign Exchange National Private Commercial Banks (BUSN), and determine the effect of profitability on firm value in Foreign Exchange National Private Commercial Banks (BUSN). This research method uses descriptive quantitative as a type of research. The population is 35 banking companies, while the sample is 17 banking companies whose financial statements are listed on the Indonesia Stock Exchange. The date were collected through secondary data in the form of documents, namely financial reports for 2016 - 2018. The data analysis technique uses multiple regression analysis. The results showed that there was no influence of managerial share ownership structure on profitability and firm value. Furthermore, there is a significant effect of public share ownership structure on profitability while firm value has no significant effect. The implication is that managerial roles and participation are needed in this case the share ownership structure in order to increase the profitability and value of banking companies such as other companies listed on the Indonesia Stock Exchange.
PREDICTING THE TECHNICAL CONDITION OF AN ELECTRIC SUBMERSIBLE PUMP BASED ON NEURAL NETWORK MODELING
Authors:   Perm National Research Polytechnic University, Karakulov I.V. , Kluiev A.V. ,   Perm National Research Polytechnic University, Stolbov V.Yu. ,   Perm National Research Polytechnic University
Published: December 2020

The problem of predicting the state of an Electric Submersible Pump during operation is considered. Downtime and shortages caused by pump failure lead to losses in oil pro-duction and require time to replace equipment. By predicting the condition of the equipment, it is possible to minimize pump maintenance costs and reduce well downtime. Expert systems and pre-dictive analytics methods are used to analyze the state of systems. The scientific work uses methods that are based on artificial neural networks. Purpose of research. Elaboration of the issues of fore-casting the technical condition of the pump through by using machine-learning models. Materials and methods. Equipment failure forecasting is carried out using time series analysis. The data was obtained from telemetric sensors of the monitoring system installed on an electric submersible pump. The initial data were taken at one-minute intervals. Initial data preprocessing was carried out. The data was cleared of values (peaks) that are clearly got out of normal operation and places where the phase voltage was equal to zero were removed. An artificial neural network with the LSTM neuron type is used to predict time series. Time series forecasting was carried out for five days. Evaluating system parameters over long periods allows you to assess the condition of its compo-nents and prevent equipment failure. Results. The possibilities of neural networks trained on the ba-sis of data from telemetric sensors of the monitoring system for predicting the values of vertical vi-bration of the pump are investigated. The use of a neural network model in the form of LSTM, which has shown good results in the analysis of time series, is justified. It was found that neural net-works capture the trend well within the time series, which indicates the possibility of using it together with the expert system. Conclusion. The proposed methods and models are tested on real data, which confirms the possibility of their use in the development of an intelligent information system for managing the technical condition of an Electric Submersible Pump during operation.
DEVELOPMENT OF AN AUTOMATIC REFLUX RATIO REGULATION SYSTEM FOR THE RECTIFICATION COLUMN
Authors:   Almetyevsk State Oil Institute, Almetyevsk, Russian Federation, Tugashova L.G. , Zatonskiy A.V. ,   Perm National Research Polytechnic University, Berezniki Branch, Berezniki,  Perm region, Russian Federation
Published: December 2020

This article provides an overview of the methods of managing the primary petroleum refining. To improve separation efficiency was proposed to stabilize the reflux ratio in the rectifying column. Purpose of work. To develop a system for automatic regulation of the reflux ratio of diesel fuel sec-tions in an atmospheric column of the refinery oil. To study the operating modes of an atmospheric column with the participation of the obtained automatic control system. Materials and methods. The article presented the features of the oil rectification process at the atmospheric unit of a small capacity refinery. The features of heat dissipation with intermediate circulation flash compared to a large-capacity unit will be shown in this article. The parameters of the facility were selected and divided into groups. A dynamic model of the section of shell-and-tube heat exchangers for heating oil with diesel fuel at a low-power refinery unit in the form of differential equations of heat balance has been developed to achieve the goal set work. An electrode dehydrator material balance equation has been compiled to find desalted oil consumption and saltwater consumption. The dependence of the reflux ratio of diesel fuel sections of the atmospheric column on the inlet and outlet temperatures of the atmospheric column circulation flash, the acute fractionation con-sumption, circulation flash, and oil fraction selection was obtained. The resulting model of the facili-ty consists of two parts: the linear part of the electric dehydrator and heat exchanger section, which determines the temperatures of the coolants, and the nonlinear output part, which determines the re-flux ratio depending on technological parameters. The proposed model makes it possible to investi-gate the effect of disturbances on the controlled parameters. The MATLAB/Simulink software prod-uct has been chosen as a tool to implement the model. A system of automatic regulation of the re-flux ratio in MATLAB/Simulink has been built with the participation of the developed model of the study object. Conclusion. The results of modeling a system for automatic regulation of the reflux ratio of diesel fuel sections in the atmospheric column of a low-power refinery unit has been ob-tained, taking into account the peculiarities of the process under disturbance conditions.
THE INFLUENCE OF PUBLIC AUTHORITIES OF THE CONSTITUENT ENTITIES OF THE RUSSIAN FEDERATION ON THE DEVELOPMENT OF INDUSTRIAL ENTERPRISES AND CORPORATIONS
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Loginovskiy O.V. , Khaldin A.S. ,   South Ural State University, Chelyabinsk, Russian Federation, Shinkarev A.A. ,   South Ural State University, Chelyabinsk, Russian Federation
Published: December 2020

It is shown that in connection with the ongoing financial and economic crises in the world, as well as a sharp aggravation of competition in the international markets of industrial products and a number of other factors, the issues of increasing the efficiency of industrial enterprises and corporations in the regions of the country need a more comprehensive and comprehensively thought-out justifica-tion. Purpose of the study. It is advisable to develop a set of scientific provisions and recommenda-tions for the analysis of the activities of industrial enterprises in the regions, which would contribute to the purposeful development of the economy of the constituent entities of the Russian Federation in modern business conditions. Materials and methods. The materials and methods used are out-lined by the content of theoretical developments and practical experience obtained in the process of researching the development of the economy and industry of the regions of the Russian Federation. Results. The list of scientific provisions and recommendations for increasing the effectiveness of the influence of state authorities of the constituent entities of the Russian Federation on the develop-ment of industry and economy of the country's regions has been substantiated. The composition of methods of state regulation in the economy and industry of the regions is presented, a list of the main tasks of the industrial and economic block for state authorities of the constituent entities of the Russian Federation, as well as the functions and mechanisms of their implementation, is pre-sented. Conclusion. The development of the economy and industry of the regions of Russia should be carried out using the scientific provisions and recommendations presented in this article, which will allow, when forming management decisions, to take into account factors and justifications that were often unused before.
EFFECTS OF ZIZIPHUS JUJUBE SUPPLEMENTATION ON PRO- AND ANTI-APOPTOTIC PROTEIN EXPRESSION IN NEUTROPHILS AFTER RESISTANCE EXERCISE
Authors: Tayebi S , Krüger K , Safakar M , Bahrami P , Tahmasb G , Nenasheva A
Published: December 2020

Introduction. It is suggested that jujube might have beneficial effects on exercise-induced immune perturbations, specifically on neutrophils apoptosis regulation, but its cellular mechanism is unclear. Aim. The aim of this study was to investigate the acute effect of Ziziphus jujuba administration on pro- and anti-apoptotic protein levels in human neutrophils in response to a session of circuit resistance exercise (Ex). Material and Methods. Participants completed an Ex (75 % 1RM, 9 exercises, 3 sets). While one group received a placebo, the other group (Zj) was supplemented daily with jujube (0.5 gr/kg body weight suspended in 2.5cc distilled water) one hour before Ex. Results. Ex increased the neutrophil level of [Ca2+]i, calpain-1 and caspase-3 (p < 0.05) while a reduction of calpastatin and XIAP were observed (p < 0.05). Zj either suppressed the [Ca2+]i or reversed the calpastatin, calpain-1, XIAP, and caspase-3 responses (p < 0.01). Conclusions. The data indicate that a single session of intensive Ex induced apoptotic signaling in human neutrophils with the involvement of [Ca2+]i-calpastatin-calpain axis upstream caspase-3. Acute administration of jujube solution before exercise attenuated these effects probably by providing energy sources for neutrophils or by functioning as antioxidants.
TEMPO AND RHYTHMIC ABILITIES IN FEMALE GYMNASTS AS A FACTOR OF MOTOR SYNCHRONICITY IN GROUP GYMNASTIC ROUTINES
Authors: Suprun A , Titova A , Borisova V
Published: December 2020

Aim. The paper aims to justify the need to take into account the tempo and rhythmic abilities of female gymnasts as one of the factors of motor synchronicity in group gymnastic routines. Materials and methods. The study involved 12 highly skilled gymnasts aged from 18 to 19 years (Masters of Sport in rhythmic gymnastics). Two groups were formed based on gymnastic routines. Tempo and rhythmic abilities were assessed, and an expert evaluation of mistakes in motor synchronicity was carried out. Results. During the expert evaluation, the athletes made errors in the following components: unintended movements in start and final positions, lack of accuracy in positions and transitions, unity of routines and composition, where one follows from the other but is evaluated by different judges. It was also determined that the rhythmic pattern with the faster tempo was done more accurately than those with the slower tempo if it was simple. The rhythmic pattern such as eighth two sixteenth and three-beat dotted causes more difficulties when performed with inner counting (p ˂ 0.05). The strongest correlations between an expert evaluation of motor synchronicity and tempo and rhythmic abilities were found for the following rhythmic patterns: two-beat dotted, three-beat dotted, syncope (r = –0.524; r = –0.485; r = –0.545). Conclusion. The tempo and rhythmic abilities of gymnasts characterize the quality of motor synchronicity in group gymnastic routines, namely, the ability of gymnasts to implement the tempo and rhythmic structure of motor actions to music.
FORMATION OF RATIONAL RHYTHMIC STRUCTURE OF RUNNING IN COMPETITIVE DISCIPLINES OF FIRE AND RESCUE SPORTS
Authors: Germanov G , Korolkov A , Shalaginov V
Published: December 2020

Aim. The paper aims to develop a methodology for a rational rhythmic structure of running in the competitive disciplines of fire and rescue sports. Materials and methods. The study involved athletes (Candidates for Master of Sport, Masters of Sport). Twenty-four people participated in the pedagogical experiment. The dynamics of the results of about 100 athletes of both sexes was analyzed. In total, over 300 races in the competitive disciplines of fire and rescue sports were included in the study. The following methods were used: video recording, electrical timekeeping; psychophysical testing (tapping test; Flamingo test, Fukuda walking test, Yarotsky test); pedagogical experiment, methods of mathematical statistics. Results. The method of formation of rational rhythmic structure of running in competitive disciplines of fire and rescue sports was developed. This method leads to minimizing errors, improving motor reliability and achieving high quantity and quality competitive results. Conclusions. The method of formation of rational rhythmic structure of running improves competitive results, provides performance enhancement in competitive disciplines of fire and rescue sports, promotes improvement of physical fitness and is suitable for both fire rescue workers and female athletes.