bluuebunny/crossref_metadata_2025 huggingface dataset:
MODELS FOR DETECTING AND FORECASTING THE DYNAMICS OF INFORMATION OPERATIONS IN SOCIAL NETWORKS
Authors:   Chernihiv Polytechnic National University, Vasylieva Olha
Published: November 2023

The article examines some provisions for conducting information operations as one of the main threats to national secu-rity in the information sphere, demonstrates the use of social networks as the main field for conducting them thanks to the latest technologies, and analyzes the proposed models of information operations in social networks.The article is devoted to the problem of the complex application of theoretical models used in the study of "viral" infor-mation dissemination in social networks of cyberspace.Formal modeling, which is used to study the peculiarities of communication in social networks, is analyzed.Three components of formal models of online message distribution in social networks are distinguished: typology of messages, network model, formal model of signal distribution.Special attention is paid to the possibilities of applying non-linear models of information dissemination.It is proposed to use a relatively new type of simulation modeling - agent-based modeling and simulation (ABMS) for modeling information operations in social networks. It is agent modeling that allows you to simulate those social processes and user behavior that occur in these new media. The main feature of agent modeling is building scenarios of possible options for the development of events in the future, on the basis of which strategic alternatives, which work in each scenario and serve as a basis for making decisions about choosing an integrated strategy are formed and then selected. The agent approach allows for multivariate situational analysis of the modeled system. The essence of the agent approach in building scenarios consistsin building an environment of active agents, determining the algorithms of their functioning and interaction, identifying new patterns, connections, cognitive connections, as well as a set of mathematical models for the formation of scenarios on a computer simulation complex. The types of virtual agents in social networks are distinguished: primary source, bot accounts, troll accounts, real people.
SOFTWARE FOR THE INFORMATION MEASURING SYSTEM EXPRESS-ANALYSIS OF SOIL PARAMETERS
Authors:   National University “Igor Sikorsky Kyiv Polytechnic Institute”, Kaliuzhna Violeta
Published: November 2023

This research paper focuses on the analysis of software for express analysis in computer-aided systems (CAS). The in-creasing demand for rapid and efficient information analysis poses challenges for the scientific and technical community to develop software tools that ensure accuracy, speed, and reliability in the process of express analysis.The problem lies in the development of software that facilitates effective CAS express analysis. It is necessary to develop software tools that can quickly and accurately process information, detect anomalies, and conduct analysis of results.The main objective of this research paper is to investigate software for express analysis in CAS and determine its effec-tiveness and practical applicability.The paper explores the fundamental aspects of software for express analysis in CAS. It analyzes various approaches and methodologies for developing such software, including requirements for functionality, architectural decisions, and data pro-cessing and analysis methods. The paper provides a concise overview of the main findings obtained during the research on software for express analysis in CAS.The application of software for express analysis in CAS proves to be highly promising and enables rapid and accurate information analysis. The developed software tools demonstrate high efficiency and practical suitability in real-world applications.
PRODUCTION OF MUTANT FORMS OF RECOMBINANT TAQ POLYMERASE IN THE ESCHERICHIA COLI
Authors:   Altai State University, Barnaul, Maslov R.D. , Balabova D.V. , Kolosov P.V. , Scherbakov D.N. ,   State Research Center of Virology and Biotechnology VECTOR, Koltsovo
Published: November 2023

Taq polymerase is a thermostable enzyme first obtained from the bacterium Thermus aquaticus and actively used in the polymerase chain reaction (PCR). Each of the three progenitor variants obtained in this work contained an expression plasmid with a mutant Taq polymerase gene. The optimal conditions for enzyme induction were determined. Three mutant Taq polymerase variants were obtained, purified, and tested for activity.
PRINCIPLES OF TERRESTRIAL INVERTEBRATES BIOMASS NUTRIENT COMPOSITION DESIGN
Authors:   Tomsk State University, Morozova M.D. , Tshernyshev S.E. , Baghirov R.T-o. , Babkina I.B. , Modyaeva V.P. , Skriptcova K.E. , Subbotina E.Yu. , Shcherbakov M.V. , Simakova A.V.
Published: November 2023

The method of providing an invertebrate biomass with particular parameters of a nutrient composition to produce biomass supplied with relatively more nutrients is discussed. An increase in the content of particular nutrients in the biomass of model species Giant African land snail Lissachatina fulica (Férussac, 1821) and the Speckled cockroach Nauphoeta cinerea (Olivier, 1789) was studied via the input of precursor material in the food substrate. A minimal input of vitamins C and B7 to the food substrate resulted in only a slight decrease in the level of protein in biomass of snails from с. 20.4 % to 18.8 % and in cockroaches from c. 8.6 to 8.0 %, but an increase in vitamins B1, B2, B3, B4 and B9 was found in the biomass of snails, and B1, B4 and B9 in cockroaches; the content of liposoluble vitamins A, E, D and K increased significantly in the biomass of cockroaches, but A, E and D increased and K decreased in snails. The content of Se, I, Pb, Hg, Mo, Ca, Na, K and Cl in the biomass of snails and of Fe, Se, Zn, Mn, Mg, P, Ca, Na, K and Cl in cockroaches also increased. It is shown, that food substrate enrichment by precursor material results in nutrient composition changes in the invertebrate biomass.
PRODUCTION OF RECOMBINANT PROTEINS AMUC_1100 AND P9 AND ASSESSMENT OF THEIR IN VITRO ANTITUMOR ACTIVITY
Authors:   SCAMTInstitute,ITMO University, Saint Petersburg, Neklesova M.V. , Deeb N.
Published: November 2023

The probiotic properties of Akkermansia muciniphila in the treatment of metabolic, cardiovascular and oncological diseases are mediated by the surface protein Amuc_1100 (Amuc) and secreted protein P9, but their combined effect has not been investigated. In this work, a recombinant producer E. coli BL21(DE3) of proteins Amuc and P9 was obtained. It is planned to conduct experiments on the colorectal cancer cell line using a combination of Amuc and P9.
CREATION AND CHARACTERIZATION OF HYDROGELS BASED ON MODIFIED PECTINS WITH CUSTOMIZABLE PROPERTIES FOR THE THERAPY OF BRAIN TUMORS
Authors:   Far Eastern Federal University, Vladivostok, Patlay A.A. , Shmelev M.E. , Silant’ev V.E. , Belousov A.S. ,   Institute of Chemistry FEB RAS, Vladivostok
Published: November 2023

We have developed pectin hydrogels and coatings suitable for remodeling the extracellular matrix of the central nervous system with adjustable viscoelastic and structural properties. Hydrogels have shown antitumor effect on glioblastoma C6 and U87MG cultures by reducing cell proliferation and migration, which makes them promising materials for combination therapy of glioma.
DEVELOPING REDOX-SENSITIVE NANOPARTICLES BASED ON TRITHIOCYANURIC ACID FOR THE TARGET DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
Authors:   ITMO University, Saint Petersburg, Kopoleva E. A. , Peltek A.
Published: November 2023

This research work is devoted to the developing of a method for the synthesis of trithiocyanuric acid (TTCA)-based nanoparticles as carriers of low molecular weight antitumour drugs. The presented work describes the method of synthesis of TTCA-based particles, their structural and morphological characterization, their sorption properties, as well as the study of the obtained nanoparticles as systems for in vitro delivery of antitumour drugs on 4T1 and A549 cell lines.
Instrumento de autoavaliação institucional para discentes de cursos de medicina
Authors: Gorayeb Adriana Letícia dos Santos , Sousa Ianny Ferreira Raiol , Furlaneto Ismari Perini , Teixeira Elizabeth , Portella Márcia Bittar
Published: November 2023

Objetivo: validar o conteúdo de um instrumento de autoavaliação institucional para os discentes de cursos de Medicina. Métodos: trata-se de um estudo metodológico com ênfase na etapa de validação de conteúdo. Participaram 15 juízes-especialistas selecionados por meio de critérios de expertise. Na coleta de dados utilizou-se um questionário com escala Likert. A análise estatística possibilitou o cálculo do Índice de Validação de Conteúdo por meio de concordância entre as respostas. Resultados: obteve-se Índice de Validação de Conteúdo global de 83,43%. A partir das sugestões relacionadas a incluir, rever, explicar, excluir, alterar, unificar, a versão final ficou com 29 questões agrupadas em quatro blocos, sendo: bloco 1 - Projeto Pedagógico do Curso; bloco 2 - Docentes; bloco 3 - Infraestrutura específica da Medicina e cenários de prática, bloco 4 - autoavaliação. Conclusão: conclui-se que o instrumento revelou-se adequado para a aplicação em processos de autoavaliação institucional. As sugestões reforçaram a necessidade e a importância de se realizar os processos de validação de conteúdo.
Impacto das condições alimentares em adultos diabéticos
Authors: Ribeiro Chan David , Santos Jair Costa dos , Costa João Gabriel Uchôa , Souza Gabriel Ribeiro de , Ferreira Luís Arthur Moreira , Leal Laís Sena , Barros Larissa Cristina Machado de
Published: November 2023

Objetivo: Analisar os impactos das condições alimentares em pacientes portadores de diabetes. Métodos: Realizou-se uma revisão integrativa da literatura para responder a seguinte questão “Quais os impactos das condições alimentares em pessoas diabéticas?”, por meio de pesquisa nas bases de dados on-line MEDLINE, LILACS e SCIELO, vinculadas à PUBMED e à BVS. Foi realizado o filtro dos estudos publicados entre janeiro de 2017 e setembro de 2022, a partir dos descritores “Diabetes Mellitus” e “Comportamento Alimentar”. Resultados: Foram encontrados 783 trabalhos, dos quais usaram 32 artigos sobre as condições econômicas, os tipos de dieta, os diferentes hábitos e as influências da COVID-19 nos pacientes com DM 2. Depreende-se dos resultados que indivíduos em estado de insegurança alimentar são os mais suscetíveis ao aumento nos índices glicêmicos. Além disso, observa-se que padrões dietéticos e hábitos alimentares específicos influenciaram ativamente no agravo ou na melhora dos pacientes. O cenário da COVID-19 afetou drasticamente a rotina dos portadores de DM 2 e, apesar de melhorias, não houve avanço na qualidade da dieta de modo geral. Considerações finais: Por meio das evidências presentes, é possível a elaboração de políticas públicas direcionadas aos adultos diabéticos para melhor manejo dessa doença crônica.
A sexualidade no planejamento assistencial de cuidados paliativos a pacientes da oncologia
Authors: Lima Claudia feio da Maia , Campos Natádina Alves Souza , Dominguez Ramona Garcia Souza , Bacelar Nidiana Evans Cabral , Souza Uilma Santos de , Marques Patrícia Figueiredo
Published: November 2023

Objetivo: Compreender como as equipes de saúde oncológica contemplam a sexualidade no planejamento assistencial de pacientes em cuidados paliativos. Métodos: Estudo qualitativo, exploratório e descritivo, realizado com profissionais de saúde. Os cenários da coleta de dados foram serviços de oncologia de um município do Recôncavo Baiano, por meio de entrevistas semiestruturadas individuais e virtuais. Para a interpretação dos dados, utilizou-se a análise de conteúdo de Bardin. Os aspectos éticos foram respeitados. Resultados: Emergiram três categorias: o conceito de sexualidade por profissionais de saúde dos serviços de oncologia; a importância da abordagem de sexualidade no planejamento assistencial a pacientes da oncologia; os desafios no planejamento assistencial à sexualidade de pacientes da oncologia. Conclusão: Os profissionais das equipes de saúde oncológica evidenciaram a falta de aproximação com o tema, além de uma visão limitada e evasiva, comprometendo o planejamento assistencial. Deve-se abordar a sexualidade de pacientes da oncologia, sistematicamente, valorizando aspectos subjetivos que configuram a sua vivência nessa dimensão humana. A enfermagem contribui ao integrar a sexualidade como premissa para um cuidado humano e inclusivo.
Diagnósticos de enfermagem em pacientes submetidos a Ressecção Transuretral de Próstata e Enucleação Prostática por Holmium Laser em um hospital universitário
Authors: Moreira Marcia Duarte , Novaes Cristiane de Oliveira , Alves Davi da Silveira Barroso , Silva Alexandre Sousa da , Gabetto Elaine Diana Kreischer , Rodrigues Midiã Almeida de Azeredo
Published: November 2023

Objetivo: Identificar os diagnósticos de enfermagem dos pacientes em pós-operatório de RTUp e HoLEP em um hospital universitário. Métodos: Estudo transversal, descritivo, retrospectivo baseado nos registros dos prontuários no período de setembro de 2021 a março de 2022. Foram analisados os diagnósticos de enfermagem segundo a taxonomia NANDA Internacional, o tempo de internação, tempo com o cateter vesical, idade, comorbidades e peso prostático. Resultados: Foram incluídos 61 prontuários com 35 cirurgias pela técnica RTUp e 26 pela HoLEP. A hipertensão foi a comorbidade mais prevalente com 50% na técnica HoLEP e 57,1% na RTUp. O tempo de internação e de cateter vesical foram significativamente menores na técnica HoLEP (p < 0,01). Os diagnósticos dor aguda e risco de retenção urinária demonstraram significância estatística (p= 0,030) e (p= 0,040) para as duas técnicas. Conclusão: Observou-se melhores desfechos para a técnica HoLEP em relação ao peso prostático, tempo de internação e uso do cateter. As frequências de ocorrências dos diagnósticos de enfermagem retenção urinária e dor aguda foram maiores na técnica RTUp com significância nas comparações.
Abordagem para tratamento de dentes desvitalizados
Authors: Farias Lorene Amorim , Cavalcante Fernanda Vitória Oliveira , Mendonça Izabel Cristina Gomes de
Published: November 2023

Objetivo: Revisar a literatura sobre a abordagem das técnicas para o tratamento de dentes escurecidos e desvitalizados. Revisão bibliográfica: Há uma variedade de técnicas, incluindo clareamento interno e restaurações estéticas. Foi evidenciado que o clareamento interno com agentes oxidantes é uma abordagem promissora para dentes desvitalizados, com resultados satisfatórios em muitos casos. Além disso, técnicas de restauração, como facetas de porcelana, demonstraram eficácia na melhoria da estética dental, especialmente em casos de escurecimento acentuado. No entanto, as limitações também foram identificadas. A sensibilidade pós-tratamento foi uma preocupação recorrente, e houve casos de resultados inconsistentes. Esses achados ressaltam a importância de avaliar cuidadosamente as opções de tratamento, levando em consideração as características individuais dos pacientes. Considerações finais: Este estudo enfatiza a necessidade de uma abordagem personalizada, discutindo expectativas realistas e possíveis complicações, como a sensibilidade. Além disso, a pesquisa contínua é crucial para aprimorar as abordagens, visando a obtenção de resultados estéticos satisfatórios e a satisfação do paciente no tratamento de dentes escurecidos e desvitalizados.
A importância do conhecimento populacional sobre prevenção e diagnóstico da doença de Alzheimer
Authors: Magalhaes Abigail Moutinho , Santos Aldus Artur Brito dos , Medeiros João Ricardo de Melo , Pereira João Victor Lobo Oliveira , Lima Anderson Bentes de , Barros Vanessa Novaes
Published: November 2023

Objetivo: Promover educação em saúde de uma população idosa de uma unidade Estratégia Saúde da Família (ESF) da região amazônica acerca da Doença de Alzheimer. Relato de experiencia: O projeto foi desenvolvido seguindo o Arco de Maguerez em que no primeiro momento, os discentes do Curso de Enfermagem realizaram uma visita a uma unidade ESF com foco em atendimento ao idoso. Nos relatos obtidos muitos idosos receberam o diagnóstico tardiamente, além disso, a população não conhecia estratégias preventivas da doença. Após um período de teorização e levantamento bibliográfico sobre a doença de Alzheimer, os pesquisadores retornaram à unidade ESF e executaram um plano de ação que envolvia educação em saúde, por meio da distribuição de folders e minipalestra sobre a doença, distribuição de caça palavras, bem como a aplicação de jogos eletrônicos mnemônicos ao grupo de idosos. Considerações finais: O desconhecimento da população é problemático para o tratamento e diagnóstico necessário da doença. Evidenciou-se que ainda há carência de informação sobre o Alzheimer, tanto em termos de compreensão da doença em si, quanto em relação às manifestações ao longo da vida do indivíduo. Nesse sentido, a abordagem estabelecida gerou engajamento e proporcionou a disseminação de informações sobre prevenção e diagnóstico da doença.
Tactics of surgical treatment of a patient with non-penetrating corneal trauma after previous femtolasic surgery (clinical case)
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Volgograd Branch, Russian Federation, Breev V.A. , Solodkova E.G. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Volgograd Branch, Russian Federation
Published: November 2023

Purpose. to present the tactics of surgical treatment of a patient with non-penetrating corneal trauma after previously undergone FemtolaSIK surgery. Material and methods. Patient m., 28 years old, addressed to the clinic of Volgograd branch with complaints of decreased visual acuity and feeling of foreign bODy on the right eye after trauma. during the repair of the braking system foreign bODies got into the right eye, which resulted in the rupture of the corneal flap in the paracentral region, with multiple metal foreign bODies getting into the corneal flap, under the corneal flap and into the stromal bed. Results. the patient underwent surgery: repositioning of the corneal flap with removal of multiple foreign bODies. mechanical partial deepithelization of the corneal flap in the zone of nonpenetrating corneal wound was performed. Foreign bODies and epithelial cells from the surface of the corneal bed and the back side of the epithelial-stromal flap were completely removed. the corneal flap was straightened and adapted. a soft contact lens was applied. Conclusion. repositioning of the corneal flap with removal of foreign bODies and epithelial cells in nonpenetrating corneal trauma allowed to preserve high visual functions in the patient after FemtolaSIK. Keywords: FemtoLASIK, keratorefractive surgery, corneal foreign body, non-penetrating corneal wound
Factors affecting the silicone oil emulsification in the vitreous cavity
Authors:   Orenburg branch of The S. Fyodorov Eye Microsurgery Federal State Institution, Firsov A.S. , Kazakova T.V. ,   Orenburg State University,   FGBNU “Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Marshinskaya O.V. ,   Orenburg State University,   FGBNU “Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Kazennov A.N. ,   Orenburg branch of The S. Fyodorov Eye Microsurgery Federal State Institution
Published: November 2023

In modern ophthalmic surgery, several types of silicone oils are used, which differ primarily in viscosity and molecular weight. Surgical treatment of severe proliferative vitreoretinopathy, severe forms of retinal detachment leads to the fact that the period of silicone oil in the vitreal cavity is delayed, and sometimes becomes lifelong. The main change that happens to silicone inside the eye is its emulsification, which creates one of the most serious problems in vitreoretinal surgery. Domestic and foreign literature sources were analyzed in this work and the main factors affecting the emulsification of silicone oil in the vitreal cavity were identified. the in vitro experiments conducted by different authors prove that such factors as the biological fluid inside the eye (blood, plasma, intraocular fluid), the severity of the inflammatory process inside the eye, tamponade term, age of patients, physical properties of silicone oil can be triggers in the development of emulsification. Emulsification of silicone oil does not occur in all cases of tamponade, which indicates that there are factors that prevent the development of emulsification, which is the subject of further study and addi Keywords: silicone, silicone oil, emulsification, secondary glaucoma
Discours des personnages de l'Octavie du Pseudo-Sénèque : Logométrie et trajet tragique
Authors: Vandersmissen Marc
Published: November 2023

Pendant longtemps, c’est la dimension historique de l’Octavie du Pseudo-Sénèque qui a intéressé les chercheurs. Ceux-ci se sont surtout concentrés sur les questions d’authenticité et de références historiques à la période néronienne. Lorsque la pièce était abordée comme une œuvre de théâtre, c’était souvent en comparaison négative avec les tragédies à sujet mythologique. Aujourd’hui, avec les outils de la logométrie, nous mettons en évidence les processus de construction des discours des personnages au service du trajet tragique des deux héros de la pièce, Octavie et Néron. Il apparaît que le couple fonctionne discursivement et tragiquement en parallèle grâce à leurs échanges avec les autres personnages. C’est parce qu’Octavie en tant que femme et Néron en tant qu’homme souffrent d’un dolor issu de leur lignée maternelle qu’ils sont contraints de se transformer sur scène en héros tragiques. En cela, l’Octavie s’inscrit dans le genre tragique tout comme les tragédies de Sénèque.
Understanding a Changing Approach to Gender in Studies on Roman Baths
Authors: Maréchal Sadi
Published: November 2023

Cet article examine comment des questions de recherche concernant le genre ont été incluses dans des études sur les bains grecs et romains. Et en outre, comment l’implication de ces questions a-t-elle influencé la perception des bains antiques ? Les premières études « antiquaires » prêtaient peu d’attention aux baigneurs, hommes ou femmes, se focalisant d’abord sur l’architecture, la technologie et la décoration de ces édifices. C’est seulement à partir de la seconde moitié du 20e siècle, poussés par des changements épistémologiques dans le domaine des sciences humaines, que les spécialistes ont commencé à inclure les femmes dans leurs discours. Trois questions ont souvent été réitérées depuis : les femmes allaient-elles aux bains publics ? Les femmes se baignaient-elles avec les hommes ? Et que portaient-elles dans les bains ? Dans la dernière décennie du siècle dernier et la première du nouveau, les études sur les bains antiques commencent progressivement à inclure des questions sur d’autres groupes de genre. Cependant, ces nouveaux discours ne sont que lentement intégrés dans les reconstructions virtuelles, qui semblent toujours très influencées par les traditionnels dessins architecturaux.
Masing Manifolds: Reconciling the Masing Conditions with Real Hysteresis in Jointed Structures
Authors: Brake M. R. W. , Porter J. H. , Karpov M. M.
Published: November 2023

The Masing conditions establish a criterion to relate the loading curve of a hysteretic system (e.g., systems with friction or plasticity) to its complete hysteresis loop. For the field of joint mechanics, where hysteretic models are often used to describe the dissipative, tangential behavior within an interface, the Masing conditions allow for significant computational savings when the normal load is constant. In practice, though, jointed systems experience time varying normal forces that modify the tangential behavior of the system. Consequently, the hysteretic behavior of jointed structures do not adhere to the Masing conditions. In this work, this discrepancy between the Masing conditions and behavior exhibited by jointed structures is explored, and it is hypothesized that if the Masing conditions accounted for variations in normal force, then they would more accurately represent jointed structures. A new set of conditions is introduced to the original set of Masing conditions, yielding a « Masing manifold » that spans the tangential displacement-tangential force-normal force space. Both a simple harmonic oscillator and a built-up structure are investigated for the case of elastic dry friction, and the results show that the hysteresis of both of these systems conforms to the three dimensional Masing manifold exactly, provided that a set of constraints are satisfied, even though the hysteresis does not conform with the original Masing conditions.
Panorama actual de la pesca ribereña en la desembocadura del río Actopan, Chachalacas, Veracruz (periodo 2014-2023)
Authors: Becerril Daniel , Monroy Dosta María del Carmen , García-López Jayro , Solano-Rendón Regina , Mata-Sotres José Antonio
Published: November 2023

Currently, human activities such as tourism, human settlements, agricultural and industrial activities have generated an alteration of the biological communities associated with the coastal zone, particularly fish communities. The coastal zones of the State of Veracruz in the Gulf of Mexico are characterized by their high biodiversity and include a great variety of fishery resources, occupying fourth place in national fish production. However, there are no recent records on the ichthyofauna of the area of Chachalacas, Veracruz. In the present study, 12 samplings were carried out from February 2014 to March 2023 at the mouth of the Actopan River in both the marine and brackish water zones. Twenty species were recorded, highlighting the white jack mackerel (Carax latus), snook (Centropomus undecimalis), ocellated croaker (Sciaenops ocellatus) and mullet (Mugil liza), as frequent species, in all sampling periods, being the latter. The mullet is the only species that has remained relatively constant in terms of the abundance of organisms caught, in contrast to the white jack mackerel, which has reduced its abundance in the area. In addition, in relation to the cpue, there is a constant decrease over the years. The results of this study will help lay the groundwork for designing management plans for fishery resources in the area of Chachalacas, Veracruz.
Key words: Ichthyofauna, Biodiversity, Fishing, Veracruz, CPUE
Clinical and diagnostic coordinates in paralityc urinary retention in companion animals
Authors: Codreanu Andrei‑Mario
Published: November 2023

In the pathology of companion animals, three main types of urinary retention are described and encountered: mechanical, spastic and paralytic. The etiopathogenesis of the pathology of paralytic urinary retention, with clinical-pathogenetic consequences that are difficult to identify and remedy therapeutically, mainly recognizes different causes, both neurogenic and traumatic. The traumatic ones are the most common and, depending on the location of the neurological injury, they influence the treatment, the evolution and also the prognosis. The present paper attempts to describe the importance of imaging examinations (both ultrasound and radiographic) in the judicious approach to patients with paralytic urinary retention.
Morpho-pathogenetic characterization of staphylococci species and strains involved in psittacine diseases
Authors: Tudor Laurențiu
Published: November 2023

The order Psittaciformes taxonomically includes the families Loriidae (Lori parrots or parakeets), Cacaduidae (crested parrots and nymph parakeets) and Psittacidae (parrots and true parakeets). The ever-increasing desire to obtain specimens with plumage and especially with spectacular chromatics led in many situations to the reproduction through repeated inbreeding and in extremely close degrees of kinship (even the repetition over several generations of mother-son or father-daughter pairings), determining, secondarily, important changes in the metabolism and immune system of the obtained products, characters that were transmitted to the following generations. The maintenance conditions are not always correlated with the needs of the respective species. In many cases, the knowledge about the eco-biology of psittacines raised in captivity is quite poor, leading to an increase in their sensitivity. In recent years, in the clinic of these bird species, we have been dealing with extremely diverse pathologies or metabolic changes that have never been described or even observed in parrots in the wild. 
Among the difficult pathological problems in terms of diagnosis and therapeutic conduct, there are infectious diseases with bacterial etiology, often confused with a series of diseases with extremely different etiologies. Some of the most common bacterial diseases in recent times are staphylococci, with various evolutions: digestive, respiratory or integumentary. The correct diagnosis, using the current laboratory methods and the morphopathogenetic knowledge of the species and strains involved, allows a rapid therapeutic intervention, with positive results.
Field Desorption Mass Spectrometric Analysis of Ethylene Polymerization Initiated by the Anthracenide Yttrium Complex, (C5H5)Y(C14H10)(THF)2.
Authors: Bardonov Daniil , Minyaev Mikhail , Roitershtein Dmitrii
Published: November 2023

Yttrium anthracenide complex CpY(C14H10)(THF)2 (1) catalyzes ethylene polymerization under mild conditions. The initiation polymerization step has been modeled by a reaction of 1 and of its Lu analog (3) with t-BuCN, resulting in the formation of mono-insertion products CpLn(-C14H10-(t-Bu)C=N-)(THF)2 (Ln= Y(5), Lu (6)). Crystal structures of 1, CpY(C14H10)(1,4-dioxane)2 (2) and 6 have been determined by the X-ray diffraction analysis. Field desorption mass spectrometry (FD MS) has been used to analyze polymerization products (oligoethylene and its copolymer with pent-1-ene) formed on 1 under various conditions. The thorough analysis of FD MS data enabled us to detect end groups and to suggest a plausible mechanism for ethylene polymerization. The proposed mechanism explains formation of all detected polymer species.
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity
Authors: Flury Philipp , Breidenbach Julian , Krüger Nadine , Voget Rabea , Schäkel Laura , Si Yaoyao , Krasniqi Vesa , Calistri Sara , Olfert Matthias , Sylvester Katharina , Rocha Cheila , Ditzinger Raphael , Rasch Alexander , Pöhlmann Stefan , Kronenberger Thales , Poso Antti , Rox Katharina , A. Laufer Stefan , E. Müller Christa , Gütschow Michael , Pillaiyar Thanigaimalai
Published: November 2023

Cathepsins (Cats) are proteases that mediate the successful entry of SARS-CoV-2 into host cells. We designed and synthesized a tailored series of 21 peptidomimetics and evaluated their inhibitory activity against human cathepsins L, B, and S. Structural diversity was realized by combinations of different C-terminal warhead functions and N-terminal capping groups, while a central Leu-Phe fragment was maintained. Several compounds were identified as promising cathepsin L and S inhibitors with Ki values in the low nanomolar to subnanomolar range, for example, the peptide aldehydes 9a and 9b (9a, 2.67 nM, CatL; 0.0455 nM, CatS; 9b, 1.76 nM, CatL; 0.0512 nM, CatS). The compounds’ inhibitory activity against the main protease of SARS-CoV-2 (Mpro) was additionally investigated. Based on the results at CatL, CatS, and Mpro, selected inhibitors were subjected to investigations of their antiviral activity in cell-based assays. In particular, the peptide nitrile 11e exhibited promising antiviral activity with an EC50 value of 35.1 nM in Calu-3 cells without showing cytotoxicity. High metabolic stability and favorable pharmacokinetic properties make 11e suitable for further preclinical development.
A Study on how Brand Positioning Helps the Business to Stand-Out Distinctively in Saturated Market: A Study With Reference to Select Supermarkets
Authors: Sanapala Gopal Krishna , Nzeku Sandile Gilbert , Mohan V. Krishna
Published: November 2023

Purpose: The purpose of this research is to examine how strategic brand positioning has affected the performance of select supermarkets stores in saturated market. This study aims to provide light on how brand positioning may contribute to market differentiation and create competitive advantage by analysing the positioning techniques used by these supermarkets and measuring consumer perceptions
 
Theoretical framework: The study demonstrates that customers are motivated to visit supermarkets based on factors such as price, quality, location, hygiene, and personal experience. However, the establishment of customer loyalty and long-term retention can only be achieved by implementing various differentiation variables of brand positioning, including segmentation, benefits offered, product class categorization, brand name, and customer relationship management.
 
Design/Methodology/Approach: The study was conducted in the city of Visakhapatnam, Andhra Pradesh, India; primary data were collected by disseminating a questionnaire via Google Form and conducting face-to-face interviews. The sample consisted of 114 participants
 
Findings: The study found that customers are motivated to visit supermarkets based on factors such as price, quality, location, hygiene, and personal experience. However, the establishment of customer loyalty and long-term retention can only be achieved by implementing various differentiation variables of brand positioning, including segmentation, benefits offered, product class categorization, brand name, and customer relationship management also it was found that ability of supermarkets to stand out significantly in a crowded market will continue to depend on their ability to establish and maintain strong relationships with their customers through effective brand positioning.
 
Research, Practical & Social implications: It is recommended that future studies emphasise the contributions by doing study on the same select supermarkets in other cities.
 
Originality/Value: The distinctive feature of this study lies in the absence of prior research conducted on the brand positioning of certain supermarkets in different cities.
The Impact of Modern Marketing Communication Tools to Increase Market Performance: The case of Commercial Bank of Ethiopia Addis Ababa
Authors: Agede Tsegaye , Prasad Swati
Published: November 2023

Purpose: The purpose of this research was to investigate the impact of modern marketing communication tools on market performance within the context of the Commercial Bank of Addis Ababa, Ethiopia. The study aimed to explore the relationships between these tools and various business outcomes such as increased sales volume, customer awareness, and market share expansion.

 

Theoretical framework: The study developed a conceptual framework based on an extensive review of existing literature. The theoretical framework provided the foundation for understanding the relationships between modern marketing communication tools, customer satisfaction, and market performance. It incorporated relevant theories and models from the field of marketing and communication.

 

Design/Methodology/Approach: The research adopted a mixed research design, combining both descriptive and explanatory methods. A quantitative research approach was employed to gather data from a sample of 384 respondents who are customers of the Commercial Bank of Ethiopia in Addis Ababa, specifically focusing on the east district. The data collection methods included questionnaires and semi-structured interviews. Additionally, secondary data was collected from academic journals, books, and online resources. The researcher utilized a convenience sampling technique for participant selection.

 

Findings: The study's findings revealed a significantly positive impact of the implementation of modern marketing communication tools on the business. These tools contributed to increased sales volume, heightened customer awareness, and expanded market share within the industry. The research also identified diverse opinions on the role of these tools in enhancing customer satisfaction and their importance in customer retention.

 

Research, Practical & social implications: The research findings have several implications for research, practice, and society. From a research perspective, the study contributes to the existing literature by providing insights into the relationship between modern marketing communication tools and market performance. Practically, the findings offer valuable insights for businesses, especially banks, on how to leverage these tools effectively to enhance their sales and customer engagement. Socially, the study highlights the importance of adopting modern marketing communication tools in businesses, potentially leading to economic growth and employment opportunities within the community.

 

Originality/Value: The originality of this research lies in its focus on the Commercial Bank of Addis Ababa, Ethiopia, examining the specific impact of modern marketing communication tools within this context. The study adds value by providing empirical evidence and practical implications for businesses operating in similar environments, offering a valuable resource for academics, practitioners, and policymakers in the field of marketing and communication.
Exploring the Efficacy of Problem-Based Learning (PBL) in Clinical Gastroenterology Education
Authors: Li Hong , Gao Rui
Published: November 2023

Purpose: To explore and analyze the effectiveness of the problem-based learning (PBL) model in clinical gastroenterology education. Methods: This study involved 40 postgraduate gastroenterology students from January 2020 to December 2021, who were randomly assigned to two groups using the random number table method: a control group (n = 20) receiving conventional teaching and a research group (n = 20) receiving the PBL model. The teaching outcomes of both groups were compared and analyzed. Results: The research group exhibited significantly high scores in both theoretical and practical examinations compared to the control group (P < 0.05). Moreover, the satisfaction levels of the trainees in the research group with the teaching model were significantly greater than those in the control group (P < 0.05). Conclusion:In the realm of clinical gastroenterology education, the PBL model proves to be an effective method for enhancing the theoretical and practical performance of postgraduate trainees. Furthermore, it garners high levels of satisfaction among students, underscoring its clear clinical value.
Instruction of Mathematics Teachers Toward Numeracy Management Program
Authors: Falcunaya Bernadette Casto
Published: November 2023

Numeracy education stands as a pivotal component of the educational landscape, necessitating attention from both administrators and teachers. To facilitate the ongoing improvement of teachers’ numeracy instructional skills, it becomes imperative to confront the barriers hindering students’ attainment of educational objectives. The purpose of the study was to evaluate the numeracy instruction provided by mathematics teachers, with an emphasis on its impact on curriculum and pedagogy enhancement. Additionally, it identified issues in the management of numeracy instruction, forming the foundation for forthcoming numeracy management initiatives targeting elementary school teachers. This study employed a researcher-developed questionnaire to conduct a descriptive survey involving 30 elementary mathematics teachers from Marawoy Elementary School. Utilizing statistical tools, specifically the mean, responses were meticulously analyzed, while issues concerning numeracy management instruction were methodically extracted and interpreted thematically. The study affirmed the robust alignment between teachers’ knowledge content and pedagogical approaches with the diverse learning needs of their students. Notably, instructional materials, classroom management, and assessment techniques exhibited variation according to students’ learning capabilities. Unfortunately, suboptimal Internet connectivity and limited access to learning resources only marginally supported the integration of technology in the teaching and learning processes. Consequently, the implementation of a numeracy management program was recommended to bridge instructional gaps among teachers in the domain of numeracy.
Coaching in the Leadership for Development-Oriented Work in Educational Organization in a Crisis Situation
Authors:   University of Primorska, Koper, Slovenia, Šlebir Lekan Helena , Istenič Andreja ,   University of Primorska, Koper, Slovenia,   University of Ljubljana, Ljubljana, Slovenia,   Kazan Federal University, Kazan, Russia
Published: November 2023

The crisis situation, the pandemic, with the closure of the educational space, has stimulated the integration of the virtual environment and digital technology into the educational space and has brought new leadership challenges. We investigated the experience of employees in the educational space (schools with adapted programmes, primary schools and secondary schools) during the pandemic. We found that employees experienced the negative aspect of facing the pandemic requirements for a virtual work environment. They were faced with the challenge of seeking help during the work process. They also had problems with remote work effectiveness, motivation and satisfaction. We were interested in the school leaders' response to work, the role of the leadership in the process of employee adaptation, and how to identify, understand and use the development tool of coaching when working in a virtual environment. A development tool is an aid to the work process, which enhances work performance. The study confirmed that a development-oriented work process depends on a higher utility value of coaching, from a positive employee response to the use of digital technologies in the work process and leaders' support in this. To the extent that employees were more open to using the Internet in the work process, they also reacted more positively to the new working conditions which required shifting online during the pandemic. A more positive response was also present in those where the leader's support was higher. We also detected a more positive response to the work process among employees who expressed an opinion about the higher useful value of coaching during the work process. We found that employees' response to online technologies was quite positive. Employees' response to the virtual work process was positive. Employees were open to the use of online technologies if the role of the employer was supportive. This leads to a better development-oriented work process.
The Fox as a Dying Hero: An Edition and Translation of the Late Medieval Icelandic Poem Skaufalabálkur
Authors: Þorgeirsson Haukur , Sayers William
Published: November 2023

The late-medieval Icelandic poem Skaufalabálkur describes the final hunting trip of an old fox in a style mimicking heroic epic. The work is traditionally connected with poets working at or near Skarð in Western-Iceland in the 15th century and we argue here that the language of the poem is consistent with that dating. This new edition presents a text of the poem based on the oldest manuscript with some advances in the reading and interpretation of certain words. The translation aims to accurately transmit the poem’s rich vocabulary pertaining to the life of foxes and medieval farming in the subarctic and to accessibly convey a satiric gem to a modern audience.
A Typology of Family Functioning at The Beginning of The COVID-19 Pandemic
Authors: Pramono Firdanianty , Lubis Djuara P.
Published: November 2023

Family functioning affects the physical and psychological health of individuals in the family. The more effortlessly a family performs its various functions, the better the mental health of its members. The purpose of this research is to analyze family issues and explore the elements that influence family functioning following the implementation of the Large Scale Social Restrictions (PSBB) policy. The research was conducted using an online survey method via Google form application. Data were collected from 18 provinces, with West Java having the highest percentage (54.8%), followed by DKI Jakarta (12.3%), Riau (7.1%), East Java (6.5%), and South Sumatra (6.0%). Data were processed using SPSS version 20, followed by descriptive and regression analysis. Based on the dimensions of family functioning, the results showed that more than 80 percent of the aspects of communication and affective responsiveness were in the low category. In comparison, more than 90 percent of responders rate their role and behavioral control as high. According to the functioning typology, as many as 64% of families have less functioning conditions, while 36% of families are still functioning well. According to the findings, the COVID-19 epidemic has also caused additional challenges for families, especially children (63.5%) and economic problems (49.5%). These findings are intended to provide useful information to the government and academia in strengthening family resilience during times of crisis.
Elementary School Students' Metacognitive Awareness: PBL Study with HPC Strategy in Science Learning
Authors: Leasa Marleny , Batlolona John Rafafy , Jamaludin Jamaludin , Nuniary Sefnath , Salhuteru Venny
Published: November 2023

The results of previous studies show that biological science learning for elementary school students is in the sufficient category. This is because teachers do not familiarize students with being trained in high-level thinking in the form of life skills, namely metacognitive awareness. Therefore, effective strategies are needed to increase students' metacognitive awareness. One model that can increase students' metacognitive awareness is the problem-based learning (PBL) model with the homogeneity psychocognition (HPC) strategy. The aim of the research is to analyze differences in elementary school students' metacognitive awareness in learning biological science using the PBL model, PBL with HPC strategies, and conventional models. This research used a quasi experiment with a pretest-posttest nonequivalent control group design. The number of samples participating in the research was 155 students where sampling was carried out randomly. The instrument used was the metacognitive awareness inventory which was adapted from the Junior Metacognitive Inventory (Jr. MAI) by Sperling et al (2002). The inventory consists of 18 questions with 9 items each on the aspects of knowledge of cognition and regulation of cognition. The research results found that there were significant differences in metacognitive awareness in the PBL learning model, PBL with HPC strategies compared to conventional learning. This research recommends that teachers can optimize PBL, as well as PBL with HPC strategies in increasing students' metacognitive awareness.
Optimalisasi Pendapatan Kelompok Pembudidaya Ikan Lele dengan Diversifikasi Olahan Pasca Panen di Pokdakan “Jabrisan Rumbuk Dadi Makmur”
Authors: Jumiati  , Suprapti Yuyun , Sri Rahmaningsih
Published: November 2023

Perikanan budidaya saat ini menjadi tren di kalangan pelaku perikanan, mengingat perikanan tangkap mulai tidak bisa maksimal dikarenakan kondisi laut mulai tercemar dan mengalami kerusakan. POKDAKAN Jabrisan Rumbuk Dadi Makmur berdiri pada November 2022 yang beranggotakan 10 pembudidaya ikan lele. Dari 10 orang pembudidaya rata-rata memiliki 10-15 kolam. Permasalahan saat ini adalah : harga lele rendah dibanding dengan harga pakan. Solusi yang ditawarkan : pembuatan olahan berbahan dasar lele, pengemasan dan pelabelan. Target kegiatan yaitu pembuatan olahan berbahan dasar ikan lele antara lain: ekado dan kaki naga; pengemasan yang menarik dan juga cara pemasaran. Indikator capaian: peningkatan pengetahuan mitra mengenai pembuatan olahan berbahan dasar ikan lele, pengemasan yang menarik sehingga produk bisa dikonsumsi semua kalangan mulai anak kecil, remaja bahkan dewasa, pemasaran juga menjadi target pelatihan karena pemasaran menjadi hal paling penting disaat kita memproduksi barang. Dari hasil pelatihan di dapatkan adanya peningkatan pengetahuan mitra minimal 46,2% diversifikasi produk. Adapun Output dari kegiatan ini adalah publikasi ilmiah di jurnal/prosiding ber ISBN, Hak Cipta, video kegiatan yang bisa diakses di media sosial