bluuebunny/crossref_metadata_2025 huggingface dataset:
Foundational Movement Skills and Play Behaviors during Recess among Preschool Children: A Compositional Analysis
Authors: Foweather Lawrence , Crotti Matteo , Foulkes Jonathan D. , O’Dwyer Mareesa V. , Utesch Till , Knowles Zoe R. , Fairclough Stuart J. , Ridgers Nicola D. , Stratton Gareth
Published: June 2021

This study aimed to examine the associations between play behaviors during preschool recess and foundational movement skills (FMS) in typically developing preschool children. One hundred and thirty-three children (55% male; mean age 4.7 ± 0.5 years) from twelve preschools were video-assessed for six locomotor and six object-control FMS using the Champs Motor Skill Protocol. A modified System for Observing Children’s Activity and Relationships during Play assessed play behaviors during preschool recess. Associations between the composition of recess play behaviors with FMS were analyzed using compositional data analysis and linear regression. Results: Relative to time spent in other types of play behaviors, time spent in play without equipment was positively associated with total and locomotor skills, while time spent in locomotion activities was negatively associated with total and locomotor skills. No associations were found between activity level and group size play behavior compositions and FMS. The findings suggest that activity type play behaviors during recess are associated with FMS. While active games without equipment appear beneficial, preschool children may need a richer playground environment, including varied fixed and portable equipment, to augment the play-based development of FMS.
Differentiation of SCC Susceptibility with EIS of Alloy 182 in High Temperature Water
Authors: Bosch Rik-Wouter , Vankeerberghen Marc
Published: June 2021

Electrochemical Impedance Spectroscopy (EIS) measurements were carried out in high temperature water with Ni-based Alloy-182. The aim was to correlate the EIS results with differences in Stress Corrosion Cracking (SCC) susceptibility that is present around the Ni-NiO transition. There was a clear difference between the EIS results at and away from the Ni-NiO transition. To make a more quantitative correlation a simple equivalent circuit was used to fit the experimental data. A clear correlation between the CPE exponent (n) and the SCC susceptibility could be obtained. Additionally, it was shown that the high frequency arc of the EIS data was related to the diffuse double layer
Interface Behavior of Brazing between Zr-Cu Filler Metal and SiC Ceramic
Authors: Zhou Bofang , Li Taohua , Zhang Hongxia , Hou Junliang
Published: June 2021

The interface behavior of brazing between Zr-Cu filler metal and SiC ceramic was investigated. Based on the brazing experiment, the formation of brazing interface products was analyzed using OM, SEM, XRD and other methods. The stable chemical potential phase diagram was established to analyze the possible diffusion path of interface elements, and then the growth behavior of the interface reaction layer was studied by establishing relevant models. The results show that the interface reaction between the active element Zr and SiC ceramic is the main reason in the brazing process the interface products are mainly ZrC and Zr2Si and the possible diffusion path of elements in the product formation process is explained. The kinetic equation of interfacial reaction layer growth is established, and the diffusion constant (2.1479 μm·s1/2) and activation energy (42.65 kJ·mol−1) are obtained. The growth kinetics equation of interfacial reaction layer thickness with holding time at different brazing temperatures is obtained.
The Influence of Water Reducing Agents on Early Hydration Property of Ferrite Aluminate Cement Paste
Authors: Huang Chunlong , Cheng Zirui , Zhao Jihui , Wang Yiren , Pang Jie
Published: June 2021

The ferrite aluminate cement (FAC) could rapidly lose fluidity or workability due to its excessive hydration rate, and greatly reduce the construction performance. Chemical admixtures are commonly used to provide the workability of cement-based materials. In this study, to ensure required fluidity of FAC, chemically different water reducing agents are incorporated into the FAC pastes. The experiments are performed with aliphatic water reducing agent (AP), polycarboxylic acid water reducing agent (PC) and melamine water reducing agent (MA), respectively. Influence of the water reducing agents on fluidity, setting time, hydration process, hydration product and zeta potential of the fresh cement pastes is investigated. The results show that PC has a better dispersion capacity compared to AP and MA. Besides decreasing water dosage, PC also acts as a retarder, significantly increasing the setting times, delaying the hydration rate and leading to less ettringite in the hydration process of FAC particles. The water reducing agents molecules are adsorbed on the surface of positively charged minerals and hydration products, however, for PC, steric hindrance from the long side chain of PC plays a critical role in dispersing cement particles, whereas AP and MA acting through an electrostatic repulsion force.
Geographic Setting and Groundwater Table Control Carbon Emission from Indonesian Peatland: A Meta-Analysis
Authors: Novita Nisa , Lestari Nurul Silva , Lugina Mega , Tiryana Tatang , Basuki Imam , Jupesta Joni
Published: June 2021

Peat restoration is a key climate mitigation action for achieving Indonesia’s Nationally Determined Contribution (NDC) emission reduction target. The level of carbon reduction resulting from peat restoration is uncertain, owing in part to diverse methodologies and land covers. In this study, a meta-analysis was conducted to assess the impact of rewetting on reduction of total CO2 in soil and heterotrophic emissions at the country level. The tier 2 emission factor associated with the land cover category in Indonesia was also calculated. The analysis included a total of 32 studies with 112 observations (data points) for total CO2 emissions and 31 observations for heterotrophic emissions in Indonesia. The results show that the land cover category is not a significant predictor of heterotrophic and total soil emissions, but the highest observed soil emissions were found in the plantation forest. Using the random-effects model, our results suggest that an increase in the water table depth of 10 cm would result in an increase in total CO2 emissions of 2.7 Mg CO2 ha−1 year−1 and an increase in heterotrophic emissions of 2.3 Mg CO2 ha−1 year−1. Our findings show that managing water table depth in degraded peatlands in various land cover types is important to achieve Indonesia’s emission reduction target by 2030.
FIELD: A Software Tool That Integrates Harvester Data and Allometric Equations for a Dynamic Estimation of Forest Harvesting Residues
Authors: Woo Heesung , Acuna Mauricio , Choi Byoungkoo , Han Sang-kyun
Published: June 2021

On an international comparison basis, Australia’s utilisation of forest residues remains very low. While there are numerous factors contributing to this low utilisation, this is greatly explained by the limited timely and accurate data on availability, quality, and location of residues generated during harvesting operations. This manuscript reports on the development and testing of a new freeware tool called FIELD (Forest Inventory Electronic Live Data), which supports the real-time monitoring and estimation of forestry harvesting residues. As inputs, FIELD uses StanForD pri files and geo-location data extracted from the harvester’s onboard computer in combination with locally developed species-specific allometric equations. Using a case study, this paper describes how FIELD works operationally and illustrates the range of support features that the tool can provide to decision-makers by producing real-time data on the availability, quality, and location of harvesting residues. In addition, it is discussed how the tool can contribute to supporting decisions during forest operations associated with the feasibility of residue utilisation in specific site conditions. Our results show that it is possible to estimate the availability of harvesting residues at geo-located sites dynamically, although further testing of the tool is required for a more accurate estimation and monitoring of harvesting residues.
A Comparative Analysis on the Effect of Variety of Grape Pomace Extracts on the Ice-Templated 3D Cryogel Features
Authors: Raschip Irina Elena , Fifere Nicusor , Dinu Maria Valentina
Published: June 2021

Nowadays, there is a growing interest in developing functional packaging materials from renewable resources containing bioactive compounds (such as polyphenols) in order to reduce the use of petroleum-based plastics and their impact on the environment. In this regard, the effect of a variety and concentration of grape pomace extracts (Feteasca Neagra or Merlot) incorporated within ice-templated 3D xanthan-based composites was evaluated by considering their water content, surface and texture properties, radical scavenging and microbiological activities. The embedding of Feteasca Neagra or Merlot grape pomace extracts was studied by static water swelling and contact angle measurements, and SEM, EDX, and TGA analyses. The water contact angle results showed an increase in the surface hydrophobicity of the extract-loaded cryogels with an increase in extract content from 10 to 40 v/v%. SEM micrographs indicated that the entrapment of grape pomace extracts affected the morphology of the pore walls and reduced the pore sizes. The antioxidant activity of grape pomace extract-loaded composite cryogels was closely related to the total phenolic content of grape variety and to their concentration into matrices. The highly hydrophobic character of composite cryogels containing Merlot grape pomace extract and their remarkable antimicrobial activity indicates a great potential of these materials for food packaging applications.
Thermo-Responsive Hydrogels: From Recent Progress to Biomedical Applications
Authors: Zhang Kaiwen , Xue Kun , Loh Xian Jun
Published: June 2021

Thermogels are also known as thermo-sensitive or thermo-responsive hydrogels and can undergo a sol–gel transition as the temperature increases. This thermogelling behavior is the result of combined action from multiscale thermo-responsive mechanisms. From micro to macro, these mechanisms can be attributed to LCST behavior, micellization, and micelle aggregation of thermogelling polymers. Due to its facile phase conversion properties, thermogels are injectable yet can form an in situ gel in the human body. Thermogels act as a useful platform biomaterial that operates at physiological body temperatures. The purpose of this review is to summarize the recent progress in thermogel research, including investigations on the thermogel gelation mechanism and its applications in drug delivery, 3D cell culture, and tissue engineering. The review also discusses emerging directions in the study of thermogels.
Molecular Breeding for Improving Productivity of Oryza sativa L. cv. Pusa 44 under Reproductive Stage Drought Stress through Introgression of a Major QTL, qDTY12.1
Authors: Oo Kyaw Swar , Krishnan Subbaiyan Gopala , Vinod Kunnummal Kurungara , Dhawan Gaurav , Dwivedi Priyanka , Kumar Pankaj , Bhowmick Prolay Kumar , Pal Madan , Chinnuswamy Viswanathan , Nagarajan Mariappan , Bollinedi Haritha , Ellur Ranjith Kumar , Singh Ashok Kumar
Published: June 2021

Increasing rice production is quintessential to the task of sustaining global food security, as a majority of the global population is dependent on rice as its staple dietary cereal. Among the various constraints affecting rice production, reproductive stage drought stress (RSDS) is a major challenge, due to its direct impact on grain yield. Several quantitative trait loci (QTLs) conferring RSDS tolerance have been identified in rice, and qDTY12.1 is one of the major QTLs reported. We report the successful introgression of qDTY12.1 into Pusa 44, a drought sensitive mega rice variety of the northwestern Indian plains. Marker-assisted backcross breeding (MABB) was adopted to transfer qDTY12.1 into Pusa 44 in three backcrosses followed by four generations of pedigree selection, leading to development of improved near isogenic lines (NILs). Having a recurrent parent genome (RPG) recovery ranging from 94.7–98.7%, the improved NILs performed 6.5 times better than Pusa 44 under RSDS, coupled with high yield under normal irrigated conditions. The MABB program has been modified so as to defer background selection until BC3F4 to accelerate generational advancements. Deploying phenotypic selection alone in the early backcross generations could help in the successful recovery of RPG. In addition, the grain quality could be recovered in the improved NILs, leading to superior selections. Owing to their improved adaptation to drought, the release of improved NILs for regions prone to intermittent drought can help enhance rice productivity and production.
Head to Head Comparison between Different 3-Dimensional Echocardiographic Rendering Tools in the Imaging of Percutaneous Edge-to-Edge Mitral Valve Repair
Authors: Tamborini Gloria , Mantegazza Valentina , Garlaschè Anna , Muratori Manuela , Fusini Laura , Ghulam Ali Sarah , Cefalù Claudia , Italiano Gianpiero , Gripari Paola , Maltagliati Anna , Penso Marco , Pepi Mauro
Published: June 2021

MitraClip (MC) is the most common percutaneous treatment for severe mitral regurgitation (MR). An accurate two-dimensional and three-dimensional echocardiographic (3DTEE) imaging is mandatory for the optimal procedural result. Recently transillumination 3DTEE rendering (3DTr) has been introduced integrating a virtual light source into the dataset and with the addition of glass effect (3DGl) allows to adjust tissue transparency improving depth perception and anatomical structure delineation in comparison with the standard 3DTEE (3DSt). The aim of this retrospective study in 30 patients undergoing MC, was to compare 3DSt, 3DTr, and 3DGl in mitral valve (MV) evaluation and procedural result assessment. 3DTEE acquisitions obtained before and after MC were processed with 3DSt, 3DTr, and 3DGl rendering. Each reconstruction was scored for quality and for ability to recognize MV anatomy, MR origin, clip position, dimension and grasping. Imaging quality was judged good or optimal in 52%, 76%, and 96% in 3DSt, 3DTr, and 3DGl reconstructions respectively. In 26/30 patients a diagnostic incremental value was found with 3DTr vs. 3DSt and in 15/26 with 3DGl vs. 3DTr and 3DSt. Only 3DGl with perpendicular cropping of the clip allowed to visualize and measure the grasped portion of each mitral leaflets. 3DTEE imaging during MC may be improved by 3DTr and 3DGl providing a better evaluation of MV, of leaflet grasping and of residual MR jets after MC.
Mass Spectrometry-Based Proteomic and Immunoproteomic Analyses of the Candida albicans Hyphal Secretome Reveal Diagnostic Biomarker Candidates for Invasive Candidiasis
Authors: Vaz Catarina , Pitarch Aida , Gómez-Molero Emilia , Amador-García Ahinara , Weig Michael , Bader Oliver , Monteoliva Lucía , Gil Concha
Published: June 2021

Invasive candidiasis (IC) is associated with high morbidity and mortality in hospitalized patients if not diagnosed early. Long-term use of central venous catheters is a predisposing factor for IC. Hyphal forms of Candida albicans (the major etiological agent of IC) are related to invasion of host tissues. The secreted proteins of hyphae are involved in virulence, host interaction, immune response, and immune evasion. To identify IC diagnostic biomarker candidates, we characterized the C. albicans hyphal secretome by gel-free proteomic analysis, and further assessed the antibody-reactivity patterns to this subproteome in serum pools from 12 patients with non-catheter-associated IC (ncIC), 11 patients with catheter-associated IC (cIC), and 11 non-IC patients. We identified 301 secreted hyphal proteins stratified to stem from the extracellular region, cell wall, cell surface, or intracellular compartments. ncIC and cIC patients had higher antibody levels to the hyphal secretome than non-IC patients. Seven secreted hyphal proteins were identified to be immunogenic (Bgl2, Eno1, Pgk1, Glx3, Sap5, Pra1 and Tdh3). Antibody-reactivity patterns to Bgl2, Eno1, Pgk1 and Glx3 discriminated IC patients from non-IC patients, while those to Sap5, Pra1 and Tdh3 differentiated between cIC and non-IC patients. These proteins may be useful for development of future IC diagnostic tests.
Reinvestigation of Carbohydrate Specificity of EBCA-1 Monoclonal Antibody Used for the Detection of Candida Mannan
Authors: Krylov Vadim B. , Solovev Arsenii S. , Puchkin Ilya A. , Yashunsky Dmitry V. , Antonets Anna V. , Kutsevalova Olga Y. , Nifantiev Nikolay E.
Published: June 2021

Monoclonal antibody EBCA-1 is used in the sandwich immune assay for the detection of circulating Candida mannan in blood sera samples for the diagnosis of invasive candidiasis. To reinvestigate carbohydrate specificity of EBCA-1, a panel of biotinylated oligosaccharides structurally related to distinct fragments of Candida mannan were loaded onto a streptavidin-coated plate to form a glycoarray. Its use demonstrated that EBCA-1 recognizes the trisaccharide β-Man-(1→2)-α-Man-(1→2)-α-Man and not homo-α-(1→2)-linked pentamannoside, as was reported previously.
Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer
Authors: Bekos Christine , Grimm Christoph , Kranawetter Marlene , Polterauer Stephan , Oberndorfer Felicitas , Tan Yen , Müllauer Leonhard , Singer Christian F.
Published: June 2021

Background: BRCA 1/2 mutation status has become one of the most important parameters for treatment decision in patients with epithelial ovarian cancer (EOC). The aim of this study was to compare tumor DNA with blood DNA sequencing to evaluate the reliability of BRCA tumor testing results. Methods: Patients who were treated for EOC between 2003 and 2019 at the Medical University of Vienna and underwent both germline (gBRCA) and tumor (tBRCA) testing for BRCA mutations were identified. We calculated the concordance rate and further analyzed discordant cases. Results: Out of 140 patients with EOC, gBRCA mutation was found in 47 (33.6%) and tBRCA mutation in 53 (37.9%) patients. Tumor testing identified an additional 9/140 (6.4%) patients with somatic BRCA mutation and negative germline testing. The comparison of germline testing with tumor testing revealed a concordance rate of 93.5% and a negative predictive value of tumor testing of 96.0%. After BRCA variants of uncertain significance were included in the analysis, concordance rate decreased to 90.9%. Conclusion: Tumor testing identified the majority of pathogenic germline BRCA mutations but missed three (2.1%) patients. In contrast, nine (6.4%) patients harboring a somatic BRCA mutation would have been missed by gBRCA testing only.
Prediction of Probable Major Depressive Disorder in the Taiwan Biobank: An Integrated Machine Learning and Genome-Wide Analysis Approach
Authors: Lin Eugene , Kuo Po-Hsiu , Lin Wan-Yu , Liu Yu-Li , Yang Albert C. , Tsai Shih-Jen
Published: June 2021

In light of recent advancements in machine learning, personalized medicine using predictive algorithms serves as an essential paradigmatic methodology. Our goal was to explore an integrated machine learning and genome-wide analysis approach which targets the prediction of probable major depressive disorder (MDD) using 9828 individuals in the Taiwan Biobank. In our analysis, we reported a genome-wide significant association with probable MDD that has not been previously identified: FBN1 on chromosome 15. Furthermore, we pinpointed 17 single nucleotide polymorphisms (SNPs) which show evidence of both associations with probable MDD and potential roles as expression quantitative trait loci (eQTLs). To predict the status of probable MDD, we established prediction models with random undersampling and synthetic minority oversampling using 17 eQTL SNPs and eight clinical variables. We utilized five state-of-the-art models: logistic ridge regression, support vector machine, C4.5 decision tree, LogitBoost, and random forests. Our data revealed that random forests had the highest performance (area under curve = 0.8905 ± 0.0088; repeated 10-fold cross-validation) among the predictive algorithms to infer complex correlations between biomarkers and probable MDD. Our study suggests that an integrated machine learning and genome-wide analysis approach may offer an advantageous method to establish bioinformatics tools for discriminating MDD patients from healthy controls.
The Effect of Risk Rating Agencies Decisions on Economic Growth and Investment in a Developing Country: The Case of South Africa
Authors: Meyer Daniel Francois , Mothibi Lerato
Published: June 2021

Over the last decade, the South African economy has endured prevailing economic challenges, including weak economic growth, unreliable electricity supply, rising fiscal deficits, declining investment inflows and the inexorable rise in government debt alongside the expected impact of the coronavirus pandemic. Credit ratings have significantly evolved, making them key elements in the modern financial markets because of their creditworthiness opinions, as many investors across the globe rely heavily on their opinions. A quantitative research approach was followed using data from 1994Q1 to 2020Q2. The analysis entailed a descriptive and econometric analysis where two models were estimated using the autoregressive distributed lag (ARDL) model. The findings reveal long-run relationships between economic growth (GDP), risk rating index, foreign direct investment (FDI), exchange rate, gross fixed capital formation and lending rates. The results also reveal a bi-directional causality between economic growth and the rating index and between FDI and the rating index. This study’s findings suggest that investments and economic growth in the country need to be stimulated significantly to impact risk rating agencies decisions. Policymakers need to redirect resources towards effective and efficient capital-forming initiatives and development projects to improve the country’s sovereign risk rating to re-ignite growth.
Unusual Force Constants Guided Distortion-Triggered Loss of Long-Range Order in Phase Change Materials
Authors: Wang Jiong , Cui Dongyu , Kong Yi , Shen Luming
Published: June 2021

Unusual force constants originating from the local charge distribution in crystalline GeTe and Sb2Te3 are observed by using the first-principles calculations. The calculated stretching force constants of the second nearest-neighbor Sb-Te and Ge-Te bonds are 0.372 and −0.085 eV/Å2, respectively, which are much lower than 1.933 eV/Å2 of the first nearest-neighbor bonds although their lengths are only 0.17 Å and 0.33 Å longer as compared to the corresponding first nearest-neighbor bonds. Moreover, the bending force constants of the first and second nearest-neighbor Ge-Ge and Sb-Sb bonds exhibit large negative values. Our first-principles molecular dynamic simulations also reveal the possible amorphization of Sb2Te3 through local distortions of the bonds with weak and strong force constants, while the crystalline structure remains by the X-ray diffraction simulation. By identifying the low or negative force constants, these weak atomic interactions are found to be responsible for triggering the collapse of the long-range order. This finding can be utilized to guide the design of functional components and devices based on phase change materials with lower energy consumption.
Leaching and VOC Emission Tests of Polymer Composites Produced from Post-Consumer Waste in Terms of Application in the Construction Sector
Authors: Kozicki Mateusz , Guzik Katarzyna , Deptuła Halina , Tomaszewska Justyna
Published: June 2021

One of the existing priorities of the European Union is to search for rational waste management and to keep such waste in the economic cycle, while meeting the highest safety requirements. The paper presents the results of environmental tests of composites based on the polyethylene (rPE) and polypropylene (rPP) matrix and reinforced with cellulose fibres (newsprint, NP). Raw materials were obtained by recycling post-consumer waste such as beverage bottles and newsprint. The composites were tested for their potential use as materials in cladding panels and acoustic barriers. Given that normative documents for these products do not define specific environmental requirements, the composites were tested for the release of dangerous substances, such as anions of inorganic compounds, heavy metals, volatile organic compounds (VOCs), and their impact on the environment. A detailed in-depth analysis of the mechanisms of release of substances (diffusion, dissolution, surface leaching and depletion) from the rPP/NP composite into surface water, groundwater and soil was carried out. In turn, emission of VOCs from the rPE (low-density:high-density (LD:HD)—50:50) and rPE (LD:HD—30:70) composites into indoor air was also carried out. Raw materials in the form of granulates and loose cellulose fibres, used to produce the composites, were also tested for their environmental impact.
Experimental Investigation of an Intensified Heat Transfer Adsorption Bed (IHTAB) Reactor Prototype
Authors: Grabowska Karolina , Zylka Anna , Kulakowska Anna , Skrobek Dorian , Krzywanski Jaroslaw , Sosnowski Marcin , Ciesielska Katarzyna , Nowak Wojciech
Published: June 2021

The first experience in the operation of intensified heat transfer adsorption bed reactor designed for low-pressure adsorption processes is presented in this paper. This work aims to assess the possibility of fluidizing the porous media bed induced by the pressure difference between the evaporator and the adsorption reactor. The conducted experimental research allowed indicating the type of silica gel recommended to use in fluidized beds of adsorption chiller. The fixed bed of silica gel was observed for the lower pressure differences, while fluidization appeared in the case of the pressure difference between the evaporator and the adsorption chamber higher than 1000 Pa. The most significant differences in the adsorption process between the fixed bed and the fluidized bed are revealed in the changes of sorbent temperatures. The silica gel bed was fluidized with water vapor generated in the evaporator.
Microstructure Investigation of Polymer Electrolyte Fuel Cell Catalyst Layers Containing Perfluorosulfonated Ionomer
Authors: Koga Maito , Matsumoto Hidetoshi , Kunishima Mitsunori , Tokita Masatoshi , Masunaga Hiroyasu , Ohta Noboru , Takeuchi Akihisa , Mizukado Junji , Sugimori Hidekazu , Shinohara Kazuhiko , Uemura Suguru , Yoshida Toshihiko , Hirai Shuichiro
Published: June 2021

Perfluorosulfonated ionomers are the most successful ion-exchange membranes at an industrial scale. One recent, cutting-edge application of perfluorosulfonated ionomers is in polymer electrolyte fuel cells (PEFCs). In PEFCs, the ionomers are used as a component of the catalyst layer (CL) in addition to functioning as a proton-exchange membrane. In this study, the microstructures in the CLs of PEFCs were characterized by combined synchrotron X-ray scattering and transmission electron microscopy (TEM) analyses. The CL comprised a catalyst, a support, and an ionomer. Fractal dimensional analysis of the combined ultrasmall- and small-angle X-ray scattering profiles indicated that the carbon-black-supported Pt catalyst (Pt/CB) surface was covered with the ionomer in the CL. Anomalous X-ray scattering revealed that the Pt catalyst nanoparticles on the carbon surfaces were aggregated in the CLs. These findings are consistent with the ionomer/catalyst microstructures and ionomer coverage on the Pt/CB surface obtained from TEM observations.
An Assessment on Average Pressure Drop and Dust-Holding Capacity of Hollow-Fiber Membranes in Air Filtration
Authors: Bulejko Pavel , Krištof Ondřej , Dohnal Miroslav
Published: June 2021

In this work, we tried to analyze dust loading behavior of polypropylene hollow fiber membranes using average pressure drop models. Hollow fiber membranes varying in fiber diameter were loaded with a standardized test dust to simulate particle-polluted air. We measured pressure drop development of the membranes at different flowrates and dust concentrations, and, after each experiment, the dust deposited on the membrane fibers was weighed to obtain dust holding capacity (DHC). The obtained experimental data was analyzed using various average pressure drop models and compared with average pressure drop obtained from pressure drop/dust load dependence using a curve fit. Exponential and polynomial fitting was used and compared. Pressure drop in relation to the dust load followed different trends depending on the experimental conditions and inner fiber diameter. At higher flowrate, the dependence was polynomial no matter what the fiber diameter. However, with higher fiber diameter at lower permeate velocities, the dependence was close to exponential curve and followed similar trends as observed in planar filter media. Dust-holding capacity of the membranes depended on the experimental conditions and was up to 21.4 g. However, higher dust holding capacity was impossible to reach no matter the experiment duration due to self-cleaning ability of the tested membranes.
FEM Simulation and Experimental Tests on the SMAW Welding of a Dissimilar T-Joint
Authors: Sepe Raffaele , Giannella Venanzio , Greco Alessandro , De Luca Alessandro
Published: June 2021

Residual stresses induced by the welding processes may, in some cases, result in significant warping and distortions that can endanger the integrity of the welded structures. This document reports an investigation of the welding process to make a dissimilar T-joint through an advanced Finite Element (FE) modelling and a dedicated laboratory test. The T-joint consisted of two plates of dissimilar materials, AISI304 and S275JR steels, both having a thickness of 5 mm, welded through a Shielded Metal Arc Welding (SMAW). Thermocouples were used to acquire the temperature variations during welding. In parallel, an FE model was built and the welding process was simulated through the “element birth and death” technique. Numerical and experimental outcomes were compared in terms of temperature distributions during welding and in terms of distortion at the end of the final cooling, showing that the FE model was able to provide a high level of accuracy.
Functionalized Mesoporous Thin Films for Biotechnology
Authors: Sartori Barbara , Amenitsch Heinz , Marmiroli Benedetta
Published: June 2021

Mesoporous materials bear great potential for biotechnological applications due to their biocompatibility and versatility. Their high surface area and pore interconnection allow the immobilization of molecules and their subsequent controlled delivery. Modifications of the mesoporous material with the addition of different chemical species, make them particularly suitable for the production of bioactive coatings. Functionalized thin films of mesoporous silica and titania can be used as scaffolds with properties as diverse as promotion of cell growth, inhibition of biofilms formation, or development of sensors based on immobilized enzymes. The possibility to pattern them increase their appeal as they can be incorporated into devices and can be tailored both with respect to architecture and functionalization. In fact, selective surface manipulation is the ground for the fabrication of advanced micro devices that combine standard micro/nanofluids with functional materials. In this review, we will present the advantages of the functionalization of silica and titania mesoporous materials deposited in thin film. Different functional groups used to modify their properties will be summarized, as well as functionalization methods and some examples of applications of modified materials, thus giving an overview of the essential role of functionalization to improve the performance of such innovative materials.
Fabrication and Characterization of Nanonet-Channel LTPS TFTs Using a Nanosphere-Assisted Patterning Technique
Authors: Yoon Gilsang , Kim Donghoon , Park Iksoo , Jin Bo , Lee Jeong-Soo
Published: June 2021

We present the fabrication and electrical characteristics of nanonet-channel (NET) low-temperature polysilicon channel (LTPS) thin-film transistors (TFTs) using a nanosphere-assisted patterning (NAP) technique. The NAP technique is introduced to form a nanonet-channel instead of the electron beam lithography (EBL) or conventional photolithography method. The size and space of the holes in the nanonet structure are well controlled by oxygen plasma treatment and a metal lift-off process. The nanonet-channel TFTs show improved electrical characteristics in terms of the ION/IOFF, threshold voltage, and subthreshold swing compared with conventional planar devices. The nanonet-channel devices also show a high immunity to hot-carrier injection and a lower variation of electrical characteristics. The standard deviation of VTH (σVTH) is reduced by 33% for a nanonet-channel device with a gate length of 3 μm, which is mainly attributed to the reduction of the grain boundary traps and enhanced gate controllability. These results suggest that the cost-effective NAP technique is promising for manufacturing high-performance nanonet-channel LTPS TFTs with lower electrical variations.
Açaí Biochar and Compost Affect the Phosphorus Sorption, Nutrient Availability, and Growth of Dioclea apurensis in Iron Mining Soil
Authors: Ramos Sílvio Junio , Pinto Duane Azevedo , Guedes Rafael Silva , Dias Yan Nunes , Caldeira Cecílio Fróis , Gastauer Markus , Souza-Filho Pedro Walfir , Fernandes Antonio Rodrigues
Published: June 2021

Organic materials, such as biochar and organic compost, can reduce P sorption mechanisms and improve soil fertility, benefiting the reclamation of areas impacted by mining. This study evaluated how the chemical properties of Fe mining soil, the adsorption of P onto this substrate, and the growth of the native plant Dioclea apurensis, were affected by the application of açaí biochar (BC), organic compost (OC), and different P doses. Substrate collected from mining soil piles was incubated for 30 days with BC or OC. Each mining substrate with or without the addition of BC or OC received five doses of P (0, 40, 80, 120, and 240 mg∙kg−1 P). The addition of BC or OC promoted an increase in pH and nutrient availability (P, K, Ca, and B) in Fe mining soil. However, plants grown in the unamended mining soil (W) showed higher growth. The maximum P adsorption capacity decreased as a function of the addition of BC. We conclude that the application of BC reduced P sorption, while the application of either OC or BC altered the chemical properties of the soil and caused contrasting effects on P dynamics in Fe mining soil, and these treatments also affected plant growth.
Au Modified F-TiO2 for Efficient Photocatalytic Synthesis of Hydrogen Peroxide
Authors: Li Lijuan , Li Bingdong , Feng Liwei , Zhang Xiaoqiu , Zhang Yuqian , Zhao Qiannan , Zuo Guifu , Meng Xianguang
Published: June 2021

In this work, Au-modified F-TiO2 is developed as a simple and efficient photocatalyst for H2O2 production under ultraviolet light. The Au/F-TiO2 photocatalyst avoids the necessity of adding fluoride into the reaction medium for enhancing H2O2 synthesis, as in a pure TiO2 reaction system. The F− modification inhibits the H2O2 decomposition through the formation of the ≡Ti–F complex. Au is an active cocatalyst for photocatalytic H2O2 production. We compared the activity of TiO2 with F− modification and without F− modification in the presence of Au, and found that the H2O2 production rate over Au/F-TiO2 reaches four times that of Au/TiO2. In situ electron spin resonance studies have shown that H2O2 is produced by stepwise single-electron oxygen reduction on the Au/F-TiO2 photocatalyst.
Rubesanolides F and G: Two Novel Lactone-Type Norditerpenoids from Isodon rubescens
Authors: He Kang , Zou Juan , Wang Yu-Xue , Zhao Chen-Liang , Ye Jiang-Hai , Zhang Jing-Jie , Pan Lu-Tai , Zhang Hong-Jie
Published: June 2021

A phytochemical investigation of the leaves of the medicinal plant Isodon rubescens led to the isolation of the two new degraded abietane lactone diterpenoids rubesanolides F (1) and G (2). Their structures were elucidated based on the analyses of the HRESIMS and 1D/2D NMR spectral data, and their absolute configurations were determined by ECD spectrum calculations and X-ray single crystal diffraction methods. Compounds 1 and 2, with a unique γ-lactone subgroup between C-8 and C-20, were found to form a carbonyl carbon at C-13 by removal of the isopropyl group in an abietane diterpene skeleton. Rubesanolide G (2) is a rare case of abietane that possesses a cis-fused configuration between rings B and C. The two isolates were evaluated for their biological activities against two cancer cell lines (A549 and HL60), three fungal strains (Candida alba, Aspergillus niger and Rhizopus nigricans) and three bacterial strains (Escherichia coli, Staphylococcus aureus and Bacillus subtilis).
A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov
Authors: Abiri Rambod , Abdul-Hamid Hazandy , Sytar Oksana , Abiri Ramin , Bezerra de Almeida Eduardo , Sharma Surender K. , Bulgakov Victor P. , Arroo Randolph R. J. , Malik Sonia
Published: June 2021

The COVID-19 pandemic, as well as the more general global increase in viral diseases, has led researchers to look to the plant kingdom as a potential source for antiviral compounds. Since ancient times, herbal medicines have been extensively applied in the treatment and prevention of various infectious diseases in different traditional systems. The purpose of this review is to highlight the potential antiviral activity of plant compounds as effective and reliable agents against viral infections, especially by viruses from the coronavirus group. Various antiviral mechanisms shown by crude plant extracts and plant-derived bioactive compounds are discussed. The understanding of the action mechanisms of complex plant extract and isolated plant-derived compounds will help pave the way towards the combat of this life-threatening disease. Further, molecular docking studies, in silico analyses of extracted compounds, and future prospects are included. The in vitro production of antiviral chemical compounds from plants using molecular pharming is also considered. Notably, hairy root cultures represent a promising and sustainable way to obtain a range of biologically active compounds that may be applied in the development of novel antiviral agents.
Effect of Phase Transformations of a Metal Component on the Magneto-Optical Properties of Thin-Films Nanocomposites (CoFeZr)x (MgF2)100−x
Authors: Ganshina Elena , Garshin Vladimir , Pripechenkov Ilya , Ivkov Sergey , Sitnikov Alexander , Domashevskaya Evelina
Published: June 2021

The results of complex studies of structural-phase transformations and magneto-optical properties of nanocomposites (CoFeZr)x (MgF2)100−x depending on the metal alloy content in the dielectric matrix are presented. Nanocomposites were deposited by ion-beam sputtering onto glass and glass-ceramic substrate. By studying the spectral and field dependences of the transversal Kerr effect (TKE), it was found that the transition of nanocomposites from superparamagnetic to the ferromagnetic state occurs in the region of xfm~30 at%, that corresponds to the onset the formation of ferromagnetic nanocrystals CoFeZr with hexagonal syngony in amorphous dielectric matrix of MgF2. With an increase of concentrations of the metal alloy for x > xfm, the features associated with structural transitions in magnetic granules are revealed in the TKE spectra. Comparison of the spectral and concentration dependences of TKE for nanocomposites on the glass and glass-ceramics substrates showed that the strongest differences occur in the region of the phase structural transition of CoFeZr nanocrystals from a hexagonal to a body-centered cubic structure at x = 38 at.% on the glass substrates and at x = 46 at.% on glass-ceramics substrates, due to different diffusion rates and different size of metal nanocrystals on amorphous glass substrates and more rough polycrystalline glass-ceramics substrates.
Chitosan-Coated Gold Nanoparticles Induce Low Cytotoxicity and Low ROS Production in Primary Leucocytes, Independent of Their Proliferative Status
Authors: Lorenzo-Anota Helen Yarimet , Zarate-Triviño Diana G. , Uribe-Echeverría Jorge Alberto , Ávila-Ávila Andrea , Rangel-López José Raúl , Martínez-Torres Ana Carolina , Rodríguez-Padilla Cristina
Published: June 2021

(1) Background: Chitosan-coated gold nanoparticles (CH-AuNPs) have important theranostic applications in biomedical sciences, including cancer research. However, although cell cytotoxicity has been studied in cancerous cells, little is known about their effect in proliferating primary leukocytes. Here, we assessed the effect of CH-AuNPs and the implication of ROS on non-cancerous endothelial and fibroblast cell lines and in proliferative lymphoid cells. (2) Methods: The Turkevich method was used to synthetize gold nanoparticles. We tested cell viability, cell death, ROS production, and cell cycle in primary lymphoid cells, compared with non-cancer and cancer cell lines. Concanavalin A (ConA) or lipopolysaccharide (LPS) were used to induce proliferation on lymphoid cells. (3) Results: CH-AuNPs presented high cytotoxicity and ROS production against cancer cells compared to non-cancer cells; they also induced a different pattern of ROS production in peripheral blood mononuclear cells (PBMCs). No significant cell-death difference was found in PBMCs, splenic mononuclear cells, and bone marrow cells (BMC) with or without a proliferative stimuli. (4) Conclusions: Taken together, our results highlight the selectivity of CH-AuNPs to cancer cells, discarding a consistent cytotoxicity upon proliferative cells including endothelial, fibroblast, and lymphoid cells, and suggest their application in cancer treatment without affecting immune cells.
Nanoparticles as a Tool in Neuro-Oncology Theranostics
Authors: Klein Andrea L. , Nugent Grant , Cavendish John , Geldenhuys Werner J. , Sriram Krishnan , Porter Dale , Fladeland Ross , Lockman Paul R. , Sherman Jonathan H.
Published: June 2021

The rapid growth of nanotechnology and the development of novel nanomaterials with unique physicochemical characteristics provides potential for the utility of nanomaterials in theranostics, including neuroimaging, for identifying neurodegenerative changes or central nervous system malignancy. Here we present a systematic and thorough review of the current evidence pertaining to the imaging characteristics of various nanomaterials, their associated toxicity profiles, and mechanisms for enhancing tropism in an effort to demonstrate the utility of nanoparticles as an imaging tool in neuro-oncology. Particular attention is given to carbon-based and metal oxide nanoparticles and their theranostic utility in MRI, CT, photoacoustic imaging, PET imaging, fluorescent and NIR fluorescent imaging, and SPECT imaging.
Effects of Conventional and Bokashi Hydroponics on Vegetative Growth, Yield and Quality Attributes of Bell Peppers
Authors: Tong René Clarisse , Whitehead Charles Stephen , Fawole Olaniyi Amos
Published: June 2021

Due to consumers’ awareness and concern about nutrition and health in different parts of the world, the adoption of organic hydroponics is increasing. This has led to a search for organic nutrient media. One of the viable nutrient sources for organic hydroponics is bokashi compost. The principal objective of this study was to compare the performance of 10% bokashi hydroponics with convention hydroponics for bell pepper production. The different hydroponics influenced vegetative growth parameters largely due to considerable differences in the mineral elements in both hydroponic systems. Stems of conventionally grown plants were significantly (p ≤ 0.05) thicker (10.2 mm) compared to those of the bokashi grown plants (7.3 mm). Conventionally grown plants had significantly (p ≤ 0.05) higher photosynthetic performance than bokashi grown plants; normalized difference vegetation index (NDVI) (78.80 versus 67.49), soil plant analysis development (SPAD; 73.89 versus 38.43), and quantum yield (QY; 0.64 versus 0.49). Leaf superoxide dismutase (SOD) activity in the leaves of bokashi grown plants (0.32 units/mg protein) was significantly (p ≤ 0.05) lower than in the leaves of conventionally grown plants (0.37 units/mg protein). This also corresponded to significantly (p ≤ 0.05) higher leaf sap content in the conventionally grown plant than bokashi grown plants. Furthermore, conventional hydroponics yielded three-fold greater pepper fruit per plant compared to bokashi. After 14 days of storage at 7 °C and 95% relative humidity, the firmness of both groups declined, especially for the bokashi grown fruit (27.73 shore unit), which was significantly lower compared to conventionally grown fruit (35.65 shore unit). However, there was an increase in carotenoid content in fruit grown in both hydroponic systems after storage. In conclusion, although bell pepper plant was successfully cultivated in bokashi hydroponics, the plant performance, fruit yield and postharvest quality were lower than conventional hydroponics. We believe that this study and its approach will provide future research with baseline information on optimizing media of bokashi hydroponics to produce bell pepper.
Effect of UV Radiation on Optical Properties and Hardness of Transparent Wood
Authors: Wachter Igor , Štefko Tomáš , Rantuch Peter , Martinka Jozef , Pastierová Alica
Published: June 2021

Optically transparent wood is a type of composite material, combining wood as a renewable resource with the optical and mechanical properties of synthetic polymers. During this study, the effect of monochromatic UV-C (λ—250 nm) radiation on transparent wood was evaluated. Samples of basswood were treated using a lignin modification method, to preserve most of the lignin, and subsequently impregnated with refractive-index-matched types of acrylic polymers (methyl methacrylate, 2-hydroxyethyl methacrylate). Optical (transmittance, colour) and mechanical (shore D hardness) properties were measured to describe the degradation process over 35 days. The transmittance of the samples was significantly decreased during the first seven days (12% EMA, 15% MMA). The average lightness of both materials decreased by 10% (EMA) and 17% (MMA), and the colour shifted towards a red and yellow area of CIE L*a*b* space coordinates. The influence of UV-C radiation on the hardness of the samples was statistically insignificant (W+MMA 84.98 ± 2.05; W+EMA 84.89 ± 2.46), therefore the hardness mainly depends on the hardness of used acrylic polymer. The obtained results can be used to assess the effect of disinfection of transparent wood surfaces with UV-C radiation (e.g., due to inactivation of SARS-CoV-2 virus) on the change of its aesthetic and mechanical properties.
Simulation Approach for Hydrophobicity Replication via Injection Molding
Authors: Baldi-Boleda Tomás , Sadeghi Ehsan , Colominas Carles , García-Granada Andrés
Published: June 2021

Nanopattern replication of complex structures by plastic injection is a challenge that requires simulations to define the right processing parameters. Previous work managed to simulate replication for single cavities in 2D and 3D, showing high performance requirements of CPU to simulate periodic trenches in 2D. This paper presents two ways to approach the simulation of replication of complex 3D hydrophobic surfaces. The first approach is based on previous CFD Ansys Fluent and compared to FE based CFD Polyflow software for the analysis of laminar flows typical in polymer processing and glass forming as well as other applications. The results showed that Polyflow was able to reduce computing time from 72 h to only 5 min as desired in the project. Furthermore, simulations carried out with Polyflow showed that higher injection and mold temperature lead to better replication of hydrophobicity in agreement with the experiments. Polyflow simulations are proved to be a good tool to define process parameters such as temperature and cycle times for nanopattern replication.