bluuebunny/crossref_metadata_2025 huggingface dataset:
PRORAČUN DVOFAZNOG SEPARATORA U OKVIRU SABIRNO-OTPREMNE NAFTNE STANICE “IĐOŠ”
Authors: Ratković Radovan
Published: November 2024

Predmet rada je proračun dvofaznog sabirnika-separatora (nafta/ voda) u okviru sabirne naftne stanice „Iđoš“. U radu je dat kratak opis sabirne stanice „Iđoš“, navedena je najvažnija oprema stanice i izvršeno je dimenzionisanje   dvofaznog separatora. U radu je ispraćena zakonska regulativa Republike Srbije iz oblasti rudarstva i prerade i transporta ugljovodonika .
ANALIZA TAČNOSTI I KVALITETA OBRADE PRI SEČENJU LASEROM
Authors: Kosanović Aleksandra
Published: November 2024

Lasersko sečenje je napredni proces čije performanse zavise od mnogobrojnih faktora. Zbog nedostatka pouzdanih praktičnih podataka o ovim faktorima, tehnologija laserskog sečenja često nije dovoljno iskorišćena. U ovom radu je korišćena Taguči metoda za identifikaciju optimalnih vrednosti ključnih parametara procesa, kao što su brzina sečenja, snaga lasera i pritisak pomoćnog gasa, kako bi se smanjili ugao nagiba reza i srednja aritmetička hrapavost. Predstavljena metodologija analize i optimizacije omogućava preciznije i kvalitetnije upravljanje procesom laserskog sečenja.
SISTEM ZA PRAĆENJE I ANALIZU ŠAHOVSKIH PARTIJA SA PLATFORME LIČES U REALNOM VREMENU
Authors: Laketić Milena
Published: November 2024

U ovom radu predstavljen je sistem za obradu i analizu podataka o šahovskim partijama prikupljenih sa platforme Ličes [1]. Glavni cilj sistema je omogućiti uvid u kvalitet partije tokom njenog odigravanja na platformi Ličes, kao i identifikacija potencijalno sumnjivih aktivnosti igrača. Kvalitet poteza analizira se koristeći šahovski alat Stokfiš [2], a igrači se na osnovu metričkih vrednosti aktivnosti mogu klasifikovati kao sumnjivi. Sistem je projektovan da bude skalabilan kako bi omogućio prikupljanje i obradu podataka u realnom vremenu.
UPOTREBLJIVOST GRAPHQL BIBLIOTEKE ZA RAZVOJ NLP INTERFEJSA
Authors: Borkovac Dragan
Published: November 2024

Konceptualno rešenje sistema koje korisnicima omogućava pristup podacima iz skladišta koristeći naredbe na prirodnom jeziku. Korisnici putem NLP interfejsa postavljaju upite na prirodnom jeziku kako bi dobili željene podatke. Sistem automatski prevodi upite na prirodnom jeziku u GraphQL upite kojim je pokriven celokupan API sistem, uključujući i skladište podataka.
POREĐENJE POKRIVENOSTI AKADEMSKIH BAZA
Authors: Ivanić Aleksa
Published: November 2024

Opis implementacije sistema za poređenje pokrivenosti akademskih baza „OpenAlex“ i „Scopus“ korišćenjem Java programskog jezika, Spring Boot radnog okvira, Elasticsearch pretraživača i React JavaScript bilioteke.
ОПТИМИЗАЦИЈА ИЗБОРА ТРАНСФОРМАТОРА И НАПОЈНИХ КАБЛОВА ЗА НАПАЈАЊЕ НОВЕ ГЛАВНЕ ЦРПНЕ СТАНИЦЕ 1 У НОВОМ САДУ
Authors: Čulić Zorica
Published: November 2024

У овом раду је обрађен избор трансформатора и расподела оптерећења по трансформаторима за напајање пумпи у Новој главној црпној станици 1, у Новом Саду. На нисконапонској страни трансформатора извршен је избор и димезионисање напојних каблова, као и прорачун за заштиту од преоптерећења и прорачун пада напона. Извршен је одабир батерија за компензацију реактивне снаге пумпи. Такође, у раду је обрађено одређивање нивоа заштите громобранске инсталације.
NAPREDNE TEHNIKE ZA SENTIMENT ANALIZU: STUDIJA KLASIFIKACIONIH I GENERATIVNIH MODELA NA ONLINE KOMENTARIMA
Authors: Mlađenović Cvijetin
Published: November 2024

Ovaj rad se bavi sentiment analizom komentara korisnika koristeći različite tehnike obrade prirodnog jezika i algoritme dubokog učenja. Implementirani su modeli poput rekurentnih neuronskih mreža (RNN), konvolutivnih neuronskih mreža (CNN), Word2Vec, GloVe, BERT, kao i generativni llama-7b-hf model. Skup podataka je preuzet sa Kaggle platforme i sadrži komentare korisnika na različite proizvode. Evaluacija modela je izvršena korišćenjem F1 mere, omogućavajući detaljnu analizu performansi u kontekstu nebalansiranih klasa. Najbolji rezultati su postignuti upotrebom transformera i SVM klasifikatora.
ОДРЕЂИВАЊЕ ПАРАМЕТАРА ЕКВИВАЛЕНТНЕ ШЕМЕ АСИНХРОНОГ МОТОРА УПОТРЕБОМ СОФТВЕРСКИХ АЛАТА
Authors: Popović Nikola
Published: November 2024

У овом раду поређене су стандардне методе добијања параметара еквивалентне шеме асихнхроног мотора са методом одређивања параметара употребом софтверских алата. Као пример коришћен је асинхрони мотор називне снаге 11 kW
ANALIZA PRELAZNIH REŽIMA NA MODELU 20[kV] MREŽE PRILIKOM AUTOMATSKOG PONOVNOG UKLJUČENJA
Authors: Gvozdenović Milan , Cvetićanin Stevan
Published: November 2024

U Matlab/Simulink okruženju nepravljen je model dvostrano napajanog 20 [kV]  voda na kome je implementirana i testirana prekostrujna zaštita sa automatskim ponovnim uključenjem (APU), a s obzirom na ograničenja koja model ima izvršeno je pravljenje modela 20[kV] izvoda baziranog na realnom izvodu 20[kV] mreže koji se može naći u praksi u okviru elektroenergetskog sistema. Model baziran na realnom izvodu 20[kV] mreže uzima u obzir stvarne karakteristike komponenti i parametre mreže. Na ovako rezvijenom modelu vršene su simulacije kratkih spojeva i analizirani su rezultati koji se razlikuju od tipa, mesta i dužine trajanja kratkog spoja. Cilj rada je analiza prelaznih procese prilikom automatskog ponovnog uključenja (APU).
KLASIFIKACIJA TIPA RADARSKOG OBJEKTA KORISTEĆI LSTM NEURONSKE MREŽE SA KONVOLUCIJAMA NA SKUPOVIMA TAČAKA
Authors: Lunić Vladimir
Published: November 2024

Rad predstavlja model neuronskih mreža za klasifikaciju tipa radaskog objekta na osnovu skupa tačaka koje definišu objekat. Arhitektura koristi konvolucije na neuređenim skupovima tačaka u okviru kratkotrajno-dugotrajne memorijske ćelije da enkodira geometriju i osobine tačaka kroz vreme. Model pokazuje visoke mere performansi na skupu podataka View of Delft sa 94% tačnosti i 0.94 F1 merom na klasama pešaka, automobila i biciklista.
SOFTVERSKO REŠENJE ZA AUTOMATIZOVANU RAZMENU ZDRAVSTVENIH KARTONA ZASNOVANO NA TEHNOLOGIJI BLOKČEJN
Authors: Jovanović Vladimir
Published: November 2024

U ovom radu predstavljeno je softversko rešenje za automatizovanu razmenu medicinskih kartona zasnovano na tehnologiji Blokčejn. Softversko rešenje obezbeđuje bezbednu razmenu podataka između zdravstvenih institucija i istraživačkih organizacija, uz očuvanje anonimnosti pacijenata. Korišćenjem pametnih ugovora,  pacijentima se omogućava potpuna kontrola nad dozvolama za pristup njihovim medicinskih kartonima. Softversko rešenje koristi tehnologije Hyperledger Fabric i MongoDB, čime se postiže skalabilnost i efikasnost u realnom vremenu, pri čemu su transparentnost i bezbednost ključni prioriteti.
ANALIZA DELOVANJA TERMIČKE ZAŠTITE KOD OPASNIH POGONSKIH STANJA ASINHRONIH MOTORA
Authors: Milošević BIljana
Published: November 2024

Ovaj rad bavi se analizom delovanja termičke zaštite kod opasnih pogonskih stanja asinhronih motora. Za tu analizu korišćen je matematički model asinhronog motora, a zatim su napravljene simulacije opasnih pogonskih stanja u Simulinku. Posmatrani su naponi, brzina i struje u ovim stanjima sa ciljem da se procenti da li će se delovati termičkom zaštitom.
JEZIK ZA SPECIFIKACIJU PRODAJNIH AKCIJA
Authors: Rajtarov Nataša
Published: November 2024

U ovom radu će biti predstavljen jezik za dinamičko kreiranje prodajnih akcija, tokom rada aplikacije, ali i kreiranje same veb aplikacije. Fokus rada je na prikazu mogućnosti i prednosti ovog jezika u odnosu na postojeća rešenja poput Vtex-a, Drools-a i JHipster-a. Cilj je da se pokaže kako kreirani jezik omogućava veću fleksibilnost i smanjuje ograničenja za prodavce prilikom kreiranja akcija, za razliku od postojećih rešenja koja se oslanjaju na šablone.
ANALIZA ALGORITAMA ROJA ČESTICA ZA PROBLEM RUTIRANJA ELEKTRIČNIH VOZILA
Authors: Radešić Nevena
Published: November 2024

Ovaj rad se bavi primjenom algoritma optimizacije rojem čestica (PSO) i njegovog unaprije­đenog oblika, generaliziranog algoritma optimizacije rojem čestica (GPSO), u rješavanju problema rutiranja električnih vozila (EVRP). Glavni cilj je poređenje per­formansi PSO i GPSO nad različitim reprezentacijama čestica, konkretno: vektora prioriteta i matrice susjedstva. Eksperimentalni rezultati pokazuju da matrična reprezentacija značajno nadmašuje vektorsku, i da GPSO algoritam postiže bolje performance od osnovnog PSO algoritma. Pored ovoga, u radu su objašnjena dva algoritma zasnovana na Belman-Fordovom algoritmu koji služe za podjelu kompletne rute na više manjih i određivanje optimalnih pozicija stanica za punjenje.
BEZBJEDNOSNA ANALIZA CAN PROTOKOLA KORIŠĆENOG U AUTOMOBILIMA
Authors: Filipović Dragana , Luburić Nikola
Published: November 2024

U ovom radu je analizirana bezbjednost vozila sa posebnim fokusom na CAN protokol i njegove komponente. Identifikovani su potencijalni napadači i detaljno su opisani njihovi ciljevi. Opisana je arhitektura automobila, s naglaskom na elektronske kontrolne jedinice i CAN protokol kao komunikacionu mrežu. Kao rezultat ovog istraživanja, razvijen je model prijetnji koji obuhvata identifikovane i analizirane prijetnje i napade na CAN protokol, pri čemu je za kategorizaciju prijetnji korišćen STRIDE okvir. Takođe su identifikovani mitigacioni mehanizmi, koji su klasifikovani u reaktivne i preventivne, te su ovi mehanizmi detaljno opisani..
IZAZOVI U KREIRANJU 2D HEKANDSLEŠ VIDEO IGRE
Authors: Svorcan Jovan
Published: November 2024

U ovom radu je opisan tok razvoja računarske igre. Opisana je radnja unutar igre kao i osnovna pravila i kako je osmišljen dizajn nivoa sa primerima. Zatim se priča o korisničkim interfejsima i modelovanju glavnog lika. Dalje se priča o elementima multimedije u igri, uključujući animacije, zvuk i boje. Na kraju je ukratko opisan i pozadinski kod koji je korišćen u igri.
The handling of the COVID-19 pandemic has faced resistance from Muslims
Authors: Karya Lestiyani Tri Endah , Armansyah Yudi , Zaki Muhammad , Serpa Sandro
Published: November 2024

This manuscript examines the resistance of Muslims to the policy of handling the COVID pandemic implemented by the Jambi city government in limiting and prohibiting congregational prayer activities, wedding celebrations, and Lebaran homecoming. This research collects qualitative data obtained through observation, interviews, and documentation. From the findings and data analysis, it is known that: first, the resistance carried out by Muslims is due to the communication and socialization carried out by the government in the COVID-19 countermeasure policy, which has not been effective, especially at the beginning of its implementation, both physical distancing, the new normal, PSBB, and PPKM policies. However, the resistance that occurs is only among the grassroots ordinary people. On the other hand, groups of Islamic religious leaders and leaders of mass organizations mostly accept the policies implemented by the government until resistance automatically disappears along with the improvement of policies carried out by the government.
A Meta-Analysis on Democracies in Indonesia
Authors: Abd. Rasyid Syamsul Bahri , Nurmandi Achmad , Salahudin  , Eka Rahmawati Dian
Published: November 2024

This research intends to describe the map of the progress of democracy studies in Indonesia. The study was performed by searching the Scopus database using the keyword “Democracy in Indonesia.” The search results are then descriptively analyzed based on the year of publishing, the number of publications, the most regularly published writer, source of the article, country of publication, and association. Data is exported in the RIS format to receive a research-creation diagram. The exported data is then interpreted and evaluated using the VOSviewer program to classify the bibliometric map and the Nvivo 12 plus software to determine the most general categorization of themes and topics. Via network visualization, lines between nodes represent the relationships (edges) between inter-nodes. The other lines of connection between nodes, the closer the relationships with records are. Meanwhile, with the visualization of density, it was seen that if the color visualized was getting redder, the subject had been researched a lot, although the topic was only barely researched if it was getting greener. Indonesia's R&D maps on democracy are grouped into six key themes: democracy, politics, social, political, local, and electoral, while political, democracy, politics, social, and growth are the most dominant themes.
Defense Policy: A Look at Bilateral Cooperation
Authors: Ashidiqi M. Marzuq , Dwi Rizky , Sasmita Anom Wahyu , Gunawan Wawan
Published: November 2024

Indonesia's friendship with Russia has existed for more than seven decades. As a country with the second largest military force in the world, Russia has always been willing to assist Indonesia in realizing the country's defence and security. The article aims to review Indonesia's cooperative relationship with Russia, especially in defence. Using the literature study method, an understanding is produced that to realize the independence of defence equipment, the Indonesian government needs to increase defence cooperation with the Russian government. At least several reasons are behind it. First, historically, Indonesia's relationship with Russia has been very close. Russia positions Indonesia as a strategic partner. This condition allows Russia to not easily impose an embargo on weapons and weapon parts to Indonesia. Second, from an economic perspective, the price of weapons sold by Russia is relatively cheaper with the same quality and reliability, even more so than weapons from other country manufacturers. And third, there is a Russian commitment to transfer technology to support the independence of Indonesia's defence equipment
How Do Informal Actors Work? Between Voter Lists and Social Pressure in Elections
Authors: Ikbal Tawakkal George Towar
Published: November 2024

Vote brokerage, as a form of brokerage activity, would have a clear and measurable commodity. Candidates will not hire vote broker when commodity can not be measured. Similarly, vote broker will not get job if there is no clear commodity that can be offered to candidate. That logic have began this study. Facts, on field indicated the debate about whether commodities (voters) actually were measured. Some brokers registered voters, and others did not, destabilizing the logic. Is vote brokerage measured and unmeasured? Do both have different measurement logic? In what did the differeneces work?. To answer these questions, I made observations and interviews in Pati at 2011-2020, where vote broker called as Sabet, and in Demak at 2015-2020, where vote broker called as Gapit. Findings, vote brokerage always measurable on two methods. Brokerage was based on list of voters name, and other was based on influence that a broker will have over voters in his respective social network. First method led to distributing money or valuable goods to voters on the list. Second method led to using social pressure to influence voters. Different type of voters made candidates assign such divergent strategies and brokerage activities to different brokers in their efforts to win elections.
Between Domestic and Commonly Known Bankruptcy Prediction Models, How Differ It Can Be?
Authors: Fiqri Aripin Muhamad
Published: November 2024

Risk Management become such an important study after 2008 Financial Crisis. As such the needs of research and improvement of Bankruptcy Prediction Models as risk assessment tool is a must. This paper will help the current and upcoming research in related fields in choosing best and suited variables and methodologies that can help revaluation and improvement bankruptcy prediction studies. This a quantitave research by using comparative associative model with non-parametric inferential analysis. To achieve the goal, this study involved four bankruptcy prediction models which two of them are commonly known models (Springate and Zmijewski) and another two are locally made by using data of Indonesia’s. The result from data analysis of 1,860 samples shows that the locally made bankruptcy prediction model or more correctly the Herlina’s Model came as the best performed model because by using suited data for certain economic and financial climate, bankruptcy prediction model can achieve a better result than commonly known models.
Considering different Montreal Cognitive Assessment cutoff scores for older adults with asthma
Authors: Moritz Gali , Becker Jacqueline H. , Ankam Jyoti V. , Arcoleo Kimberly , Wysocki Matthew , Holtzer Roee , Wisnivesky Juan , Busse Paula J. , Federman Alex D. , Jariwala Sunit P. , Feldman Jonathan M.
Published: November 2024

Background: There is a greater prevalence of cognitive impairment among ethnic and/or racial minorities, and cognitive impairment is a barrier to asthma self-management (SM) behaviors and outcomes in older adults. Objective: The aim of this study was to
examine the relationship between cognitive impairment, assessed by using the Montreal Cognitive Assessment (MoCA), and asthma SM behaviors and outcomes in a sample of predominantly Black and Latino participants. In addition, we evaluated whether using two different MoCA cutoff scores influenced
the association between cognitive impairment and asthma outcomes. Methods: Baseline cross-sectional data were extracted from a longitudinal study of older adults with asthma (N = 165) ages ≥60 years. Cognition was assessed by using the MoCA. Asthma Control Questionnaire,
asthma-related quality of life (AQOL), and inhaled corticosteroid (ICS) adherence were assessed by using self-report. ICS dosing was collected through chart review and inhaler technique was observed and rated. Results: Using established MoCA cutoff scores of 23 and 26 yielded
45% and 74% cognitive impairment rates, respectively. Cognitive impairment, defined by using the cutoff score of 23, was significantly associated with worse asthma control (p = 0.04) and worse ICS adherence (p = 0.01). With a cutoff score of 26, only AQOL was significantly associated with
cognitive impairment (p = 0.03). Race and/or ethnicity moderated the relationship between cognitive impairment and asthma control with a MoCA cutoff score of 23, and between cognitive impairment and AQOL with a MoCA cutoff score of 26. Conclusion: Cognitive impairment in
older adults with asthma is associated with important clinical outcomes, but this relationship is influenced by the cutoff score used to define cognitive impairment.
Dupilumab rapidly improves eustachian tube dysfunction and otologic symptoms in aspirin-exacerbated respiratory disease
Authors: Mullur Jyotsna , Lundberg Marie , Maurer Rie , Laidlaw Tanya M. , Buchheit Kathleen M.
Published: November 2024

Background: Patients with aspirin-exacerbated respiratory disease (AERD) frequently experience symptoms consistent with eustachian tube dysfunction (ETD), which can substantially impair patient quality of life. Methods: We analyzed a cohort of 98 adult
patients with AERD who participated in a longitudinal, survey-based study. Results: By assessing data over 1 year, we established that, in patients with AERD, the ear/facial subdomain of the 22-item Sino-Nasal Outcome Test (SNOT-22) questionnaire could predict performance
on the 7-item Eustachian Tube Dysfunction Questionnaire, a validated instrument for the diagnosis of ETD. We then performed a re-analysis of data from a prospective, open-label study of 22 adult patients with AERD treated with dupilumab for 3 months. We found that treatment with dupilumab
was associated with a significant decrease in the SNOT-22 ear/facial subdomain score, which reflects a substantial reduction in otologic symptoms and ETD within 1 month of initiating dupilumab and was sustained for 3 months afterward. Conclusion: Our findings provide evidence
that dupilumab significantly improved ETD and otologic symptoms in AERD, evidenced by changes in the SNOT-22 ear/facial subdomain score. The presence of ETD and otologic symptoms should be considered when determining the optimal therapeutic course for patients with AERD.
The use of biologics in food allergy management
Authors: Shaker Marcus S.
Published: November 2024

Patients and families living with food allergy may experience significant burdens, including social isolation, impaired quality of life, and anxiety. Allergists/immunologists play a critical role in educating families living with food allergies about risk, particularly with regard to
the rarity of fatal food allergy. Appropriate risk framing can greatly decrease the fear-based burden of disease. In 2024, an increasing complex fabric of food allergy treatments has emerged that includes oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and omalizumab, with the promise
of additional treatments, including epicutaneous immunotherapy and oral mucosal immunotherapy in the near future. Younger children may be most likely to benefit from OIT and SLIT, with some evidence that suggests the possibility of an immunomodulatory effect. Omalizumab, approved in 2024 for
use in conjunction with strict avoidance, increases the threshold of reactivity before a moderate-to-severe reaction for many, but not all, patients. There is no evidence to date that omalizumab has an immunomodulatory effect, and young children treated with omalizumab monotherapy may bear
a lost opportunity cost from possible immunomodulation would they have been treated with OIT or SLIT instead; however, within a shared decision-making paradigm, beyond label use of omalizumab may include treatment with OIT or SLIT. Fortunately, the co-evolution of shared decision-making with
modern food allergy treatments will facilitate the critical preference-sensitive care that must be characteristic of all decisions surrounding active food allergy management.
Assessment of pediatric patients with suspected nonsteroidal anti-inflammatory drug hypersensitivity
Authors: Dogan Selcuk , Ertugrul Aysegul , Ozer Murat , Severcan Ezgi Ulusoy , Sirin Seda , Ozmen Serap
Published: November 2024

Background: Beta-lactam antibiotics are the most common cause of hypersensitivity reactions to medications, followed by nonsteroidal anti-inflammatory drugs (NSAID). Objective: The aim of this study was to classify children with hypersensitivity reactions
to nonsteroidal anti-inflammatory drugs (NSAID-H) according to the latest updates. Methods: ENDA recommendations were used to evaluate all patients with suspected NSAID-H. Children were classified as either selective responders (SR) or cross-intolerant based on the results
of the drug provocation test (DPT). Results: Sixty-seven patients with suspected NSAID-H were evaluated in this study. NSAID-H was confirmed in 20 patients (29.9%). Among the 20 patients diagnosed with NSAID-H, 15 were classified according to the 2018 EAACI/ENDA Position
Paper. Twelve patients (80%) were classified as cross-intolerant and 3 (20%) as SRs. NSAID-H was confirmed in 4 of 37 patients (10.8%) ages <10 years and 16 of 30 patients (53.3%) ages >10 years (p < 0.001). Twelve patients ages >10 years were classified. Cross-intolerance
was detected in nine patients (66.6%). In patients >10 years of age, NSAID-induced urticaria/angioedema (NIUA) (16.7%) was the most common type in the group with classifiable cross-intolerant. In addition, NSAID-exacerbated respiratory disease was detected in one patient. Conculsion:
Ibuprofen is the most common NSAID-H drug used in children. NIUA is the most common reaction. In pediatric allergy, hypersensitivity to NSAIDs is a challenging diagnostic issue. Hypersensitivity to NSAIDs poses a challenging diagnostic issue in pediatric allergies. The oral challenge test
is the main diagnostic tool; however, in clinical practice, performing multiple challenge tests is difficult.
The utility of shared decision making in the management of hereditary angioedema
Authors: Odin Rachel , Anderson John , Jacobs Joshua , Jones Douglas , Li H. Henry , Lumry William , Manning Michael , Soteres Daniel , Tachdjian Raffi , Yang William , Bernstein Jonathan A.
Published: November 2024

Background: Hereditary angioedema (HAE) is a complex disorder with a wide array of treatment options. Shared decision-making (SDM) should be used to ensure that patients are choosing their best treatment option. The goal was to develop and psychometrically test a brief instrument
for assessing the patient’s perspective of the SDM process during his or her clinical encounters with an HAE specialist/allergist. Method: We hypothesized that SDM could be used effectively to help patients in their choice of therapy for HAE. Ten HAE treating physicians
from the United States with a total of 50 patients with HAE used SDM to help patients choose the best prophylactic therapies (oral kallikrein inhibitor, androgens, subcutaneous C1 inhibitor replacement therapy, intravenous C1 inhibitor replacement therapy, monoclonal antibody kallikrein inhibitor)
for their HAE and then completed surveys to analyze the effectiveness of the implementation of SDM as a quality indicator in health services assessment. Results: The congruence of answers between the physicians and the patients was then analyzed; 90% of the patient-physician
pairs agreed that the advantages and disadvantages of the treatment options were precisely explained; 92% of the patient-physician pairs agreed that the physician helped them understand all the information and that the physician asked them which treatment option they preferred; 88% of the
pairs agreed that the different treatment options were thoroughly weighed and 92% of the pairs felt that they selected a treatment option together. Conclusion: In summary, SDM is being implemented by treating physicians to determine the best management options for their
patients with HAE.
Ultrafiltered dog allergen skin test compared with acetone precipitated and conventional dog: A retrospective study
Authors: Pollock Joshua , Watson Nora , Pittman Luke , Schwartz David
Published: November 2024

Background: Various formulations of dog allergen extracts, including conventional dog (also known as dog epithelium) and acetone precipitated (AP) dog, have been used for skin-prick testing (SPT), with AP dog showing improved antigen content but experiencing stability issues
due to precipitant formation. Ultrafiltered (UF) dog extract has been developed to address these concerns by offering comparable allergen content to AP dog. This study retrospectively compared UF dog with conventional dog and AP dog in SPT. Objective: To compare the efficacy
of UF dog extract with conventional dog and AP dog extracts in detecting dog sensitization through SPT. Methods: Retrospective analysis of SPT results from a single U.S. allergy clinic was conducted. Tests performed between October 2022 and March 2024 were included. Primary
and secondary outcomes were analyzed by using descriptive statistics and statistical tests. Results: UF dog, AP dog, and conventional dog showed positivity rates of 24.2%, 23.5%, and 16.3%, respectively. UF dog demonstrated significantly higher average wheal and erythema
sizes compared with conventional dog and AP dog, but UF dog was not statistically different from AP dog in terms of test positivity. Conclusion: UF dog extract showed comparable number of positive tests to AP dog and a greater number of positive tests to conventional dog.
Results of the study suggest UF dog as a viable alternative to AP dog, which offered improved stability and similar test responses. Further research with larger sample sizes is recommended to confirm these findings.
A case of a rash after tetanus-diphtheria-pertussis and meningococcal vaccination
Authors: Salazar Leonardo , Acevedo Joanne , Adame Fiona , Kelly Brent , Covington Cleavon
Published: November 2024

We present a case of a 12-year-old healthy girl who presented with acute onset of dry, hyperpigmented, and raised pruritic rash. The lesions initially presented on her thighs then progressed to the trunk and arms hours after receiving the tetanus-diphtheria-pertussis (Tdap) and meningococcal
vaccine. After a poor response to medium potency topical steroids, a biopsy specimen was taken, which led to our diagnosis. Current literature reports this condition occurring after Tdap; measles, mumps, and rubella; and COVID-19 vaccinations; but, to our knowledge, not after meningitis vaccines.
The role that vaccines play in the pathophysiology remains unclear. This condition may get mistaken for an allergic reaction and lead to vaccine avoidance.
A systematic review and meta-analysis exploring the bidirectional association between asthma and gastroesophageal reflux disease in children
Authors: Zheng KaiWen , Wang Xiang , Tang LinYan , Chen Ling , Zhao YuLing , Chen Xing
Published: November 2024

Background: Asthma is the most prevalent chronic respiratory disease in children, and gastroesophageal reflux disease (GERD) is one of its extraesophageal complications of asthma. Both conditions are commonly observed in pediatric outpatient clinics, but the causality between
them in children is still debated. Therefore, we conducted a systematic review and meta-analysis to evaluate the bidirectional association between asthma and GERD in children. Methods: We systematically reviewed original studies published from January 2000 to February 2024
by searching the data bases. We also performed manual retrieval and screening to identify studies that met the inclusion criteria. The quality of the final included studies was evaluated by using the Newcastle‐Ottawa Scale, and outcome measures were extracted. Results:
We identified nine eligible studies, which included 304,399 children of different ages from seven countries. Overall, the risk of developing GERD in children with asthma (odds ratio [OR] 2.16 [95% confidence interval [CI], 1.6‐2.91) was higher than the risk of developing asthma
in children with GERD (OR 1.55 [95% CI, 1.32‐1.82]). Conclusion: Based on the available studies, it can be concluded that asthma and GERD are mutually aggravating factors in children, presenting a bidirectional association. However, the risk of developing GERD in
children with asthma is higher to some extent. More large-scale and high-quality prospective cohort studies are needed in the future to provide richer evidence and more research opportunities.
COVID-19 and severe cutaneous allergic reactions to sulfonamides
Authors: Deng Elen , Craig Timothy J. , Nguyen Dinh V. , Al-Shaikhly Taha
Published: November 2024

Background: Sulfonamides are associated with severe cutaneous adverse reactions (SCARs). Coronavirus disease 2019 (COVID-19) triggers an immune response, which may increase the likelihood of developing a hypersensitivity reaction. Objectives: We sought
to explore the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the probability of developing SCARs and/or erythema multiforme (EM) reactions to sulfonamides. Methods: In the propensity score-matched cohort study by using the de-identified
TriNetX Research data base, patients who had an exposure to antibiotic or non-antibiotic sulfonamides between March 1, 2020, and January 1, 2023, were divided into two groups based on the presence or absence of a previous COVID-19 infection within 6 months of starting the sulfonamide agent.
The outcomes studied were the 30-day risk of developing SCARs or EM (Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, or EM) within 3 months of sulfonamide exposure. Cohorts were matched based on baseline demographics; malignant lymphoid
neoplasms; human immunodeficiency virus; systemic lupus erythematosus; bone marrow transplantation; diabetes; psoriasis; seizures; gout; solid organ or stem cell transplantation; COVID-19 vaccination; and exposure to risk medications, including allopurinol, levetiracetam, carbamazepine, lamotrigine,
oxcarbazepine, phenytoin, phenobarbital, abacavir, nevirapine, piroxicam, tenoxicam, or mexiletine. Results: When comparing 345,119 patients on sulfonamides and with previous COVID-19 to an equal number of sulfonamides users without a previous COVID-19, patients with COVID-19
had a lower risk of developing any form of SCARs (relative risk 0.39 [95% confidence interval, 0.26, 0.58]; p < 0.001). Conclusion: Previous SARS-CoV-2 infection seems to be associated with a lower probability of developing SCARs or EM among patients using
sulfonamides.
Effects of storage temperature on throat swabs preserved in different transport media for detection of SARS-CoV-2 by reverse transcriptase polymerase chain reaction
Authors: Verma Lalita , Hooja Saroj , Yadav Rajeev , Pal Nita , Ranawat Kaamini , Malhotra Bharti
Published: November 2024

Objectives:

The coronavirus disease 2019 (COVID-19) pandemic resulted in an increased need for molecular diagnostic testing. Delay in the specimen processing and storage of samples in laboratories leads to degradation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA. Inactivation transport medium (ITM) contains chaotropic agents that inactivate the virus and stabilize SARS-CoV-2 RNA for a longer duration, even at room temperature. The effect of different temperatures and duration of storage of samples in viral transport media (VTM) and ITM for detection of SARS-CoV-2 RNA was assessed.

Materials and Methods:

Samples from COVID-19 patients were aliquoted in ITM and VTM and kept at ambient temperature, 37°C and 45°C. SARS-CoV-2 viral RNA was extracted. Multiplex real-time polymerase chain reaction was done on days 0, 1, 3, and 5, and cycle threshold (Ct) values were noted.

Statistical Analysis:

Data were analyzed using the Statistical Package for the Social Sciences version 26.0. Linear variables were summarized as mean and standard deviations. One-way analysis of variance test with post hoc Tukey honestly significant difference was used to compare mean value between different loops and for pair-wise comparison. P < 0.05 was taken as significant.

Results:

The mean Ct values of both the Orf and E genes of the samples in VTM and ITM were stable across all temperature conditions on day 1. On day 5, the increase in Ct values for both E and Orf genes were significantly higher for VTM than ITM at ambient temperature, 37°C and 45°C. Ribonuclease P failure was significantly higher for VTM than ITM at ambient temperature and 37°C on day 3 and at all temperatures on day 5.

Conclusions:

ITM is a valuable transport media that can preserve SARS-CoV-2 for up to 5 days at ambient temperature and 37°C. As it renders the samples non-infectious, thus reducing the potential of biohazard events, this transport medium can be used effectively for the collection and transportation of SARS-CoV-2 samples, especially from remote or isolated healthcare facilities.
РАЗРАБОТКА НОВЫХ АППАРАТОВ ДЛЯ СМЕШЕНИЯ СЫПУЧИХ СРЕД С ПОДВИЖНЫМИ РАССЕИВАТЕЛЯМИ
Authors: Д.В. Лебедев , А.А. Ватагин , А.Е. Лебедев , А.Б. Капранова , И.С. Гуданов , Д.С. Долгин
Published: November 2024

В химической и других отраслях промышленности при проведении процессов смешивания сыпучих сред достаточно часто имеет место возникновение нежелательного процесса – сегрегации смеси, то есть ее разделение в процессе получения и выгрузки [1, 2]. Наличие сегрегации существенно ухудшает ее однородность, повышает время смешивания и увеличивает затраты энергии. Установлено, что наиболее интенсивная сегрегация вызвана различием плотностей и размеров частиц смешиваемых материалов. Кроме того, процесс сегрегации также происходит при выгрузке готовой смеси, тем самым нарушая (ухудшая однородность) сформировавшуюся смесь. При смешивании сыпучих сред во многих процессах химических технологий наибольшая интенсивность разделения смеси происходит из-за сегрегации по плотности и размерам. Большинство смесителей хорошо справляются со своей задачей. Это характерно для тех случаев, когда частицы имеют близкие размеры, плотность, форму и другие параметры. Однако при смешивании материалов, частицы которых отличаются по вышеуказанным признакам, часто имеет место сегрегация – явление, приводящие к разделению смеси. Для смешивания таких материалов необходимо использовать специальное смесительное оборудование, позволяющие нейтрализовать эффект сегрегации [1, 2].

In chemical and other industries, when mixing bulk media, an undesirable process often occurs – segregation of the mixture, that is, its separation during receipt and unloading [1, 2]. The presence of segregation significantly worsens its uniformity, increases mixing time and increases energy costs. It has been found that the most intense segregation is caused by the difference in the densities and particle sizes of the materials being mixed. In addition, the segregation process also occurs when unloading the finished mixture, thereby disrupting (worsening the uniformity) of the formed mixture. When mixing bulk media in many processes of chemical technologies, the greatest intensity of separation of the mixture occurs due to segregation in density and size. Most faucets do their job well. This is typical for those cases when the particles have similar sizes, density, shape and other parameters. However, when mixing materials whose particles differ in the above characteristics, segregation often occurs – a phenomenon that leads to the separation of the mixture. To mix such materials, it is necessary to use special mixing equipment to neutralize the effect of segregation [1, 2].
ПРИМЕНЕНИЕ ОЦЕНКИ НЕОПРЕДЕЛЕННОСТИ РЕЗУЛЬТАТА ИЗМЕРЕНИЯ ДЛЯ ОПРЕДЕЛЕНИЯ ПОКАЗАТЕЛЕЙ КАЧЕСТВА ОБРАЗЦОВ РАВНОВЕСНОГО КАТАЛИЗАТОРА КРЕКИНГА
Authors: А.А. Егорова , Л.Г. Варепо
Published: November 2024

При производстве катализаторов основным показателем качества является содержание в них различных веществ. Знание химического состава выпускаемой продукции необходимо для выпуска качественных и безопасных катализаторов, удовлетворяющих заявленным продавцом характеристикам. В связи с обновлением парка приборов для контроля и повышения точности показателей качества в процессе производства современных катализаторов нефтепереработки необходимо вводить новые методики испытаний с использованием более точного оборудования и совершенствовать метрологическое обеспечение. В данной работе проведен сравнительный анализ результатов определения массовой доли оксидов натрия, железа, алюминия и редкоземельных элементов образца равновесного катализатора крекинга с использованием AAnalyst 400, UNICO-1200, метода титрования с результатами, полученными при помощи Avio 200.Погрешность измерения показателей качества катализаторов оценивали с учетом неопределенности результата измерения.

In the production of catalysts, the main indicator of quality is the content of various substances in them. Knowledge of the chemical composition of manufactured products is necessary to produce high-quality and safe catalysts that meet the characteristics declared by the seller. In connection with updating the fleet of instruments for monitoring and increasing the accuracy of quality indicators in the production process of modern oil refining catalysts, it is necessary to introduce new test methods using more accurate equipment and improve metrological support. In this work, a comparative analysis of the results of determining the mass fraction of oxides of sodium, iron, aluminum and rare earth elements of a sample of an equilibrium cracking catalyst using the AAnalyst 400, UNICO-1200, titration method with the results obtained using Avio 200 was carried out. The error in measuring the quality indicators of the catalysts was assessed with considering the uncertainty of the measurement result.
Markets of agro-industrial complex products in conditions of geoeconomic fragmentation of the international trade
Authors: Smirnov E. N. , Karelina E. A. , Pletnev M. G.
Published: November 2024

For decades, international trade has contributed to the reduction of global poverty and the income gap between countries, and the development of intercountry exchange of agricultural products has largely ensured the solution of problems of poverty and food security. At the same time, at the present stage, a high degree of dependence of many developing countries on food imports has occured, while its global exporters have faced a number of restrictions on the supply of their agricultural products. This article analyses the impact of geoeconomic fragmentation of the international trade on the development of exports and imports of products of the agro-industrial complex (hereinafter referred to as AIC). In particular, the problems of competition in the world agro-food markets are discussed in a new context, since the growing problems of monopolisation in certain segments of the AIC disrupt the stability of agricultural markets. Exclusive attention is paid to the key aspects of the application of non-tariff measures in regulating trade of the agricultural products, which, in addition to the protective role, can have a distorting effect on world prices. Our analysis places particular emphasis on the hidden costs of global agri-food systems, which necessitate their rapid modernisation to ensure sustainability in the development of the agricultural markets and to address global food security issues.
Factors of employment of graduates of higher educational institutions in Guinea
Authors: Traore A. , Kazantseva N. V.
Published: November 2024

Employment of higher education graduates is a challenge for governments in both developed and developing countries. This article highlights factors that explain the professional integration of graduates leaving universities. This study demonstrates the variables influencing the employment of young tertiary graduates. The model used allows us to establish economic relationships between exogenous and endogenous variables. The variables are qualitative and dichotomous in nature with multiple modalities. The presented results allow us to determine which exogenous variable has a greater impact on the endogenous variable so that governments can consider it in youth employment policies. We also advise young graduates in terms of finding a job. The purpose of this study is to promote the professional integration of Guinean higher education graduates. The main objective is to identify the problems faced in the labour market by Guinean higher education graduates. Using SPSS software, we have obtained the following results: the higher the level of education, the greater the chances of finding a job; personal initiative gives a better chance of finding a job than any other method of finding a job; men have an advantage over women in terms of employment opportunities; married people are luckier than single people; those who have had a previous job are also more likely to find a job than those who have not had; graduates who have lived abroad are more likely to find a job than those who have not lived abroad.
Improving the budgetary policy of municipalities
Authors: Urusova A. B.
Published: November 2024

The subject of the study is financial relations of municipalities in terms of income generation. The purpose of the article is to disclose and justify measures to increase fairness of the distribution of personal income tax by fixing the share of such a tax for the municipality in which the citizen lives but does not work. The research methods are general scientific (analysis, synthesis, deduction, classification, work with sources) and empirical ones (horizontal analysis). The article considers the problem of imbalance of local budgets caused by pendulum migration and, consequently, by outflow of income from municipalities. An information and software solution has been proposed to ensure the fair distribution of part of the personal income tax between municipalities by the place of residence and work of taxpayers. The logical model of the proposed solution and necessary changes in legislation for its implementation are described. The scope of application is the budget system of the Russian Federation, namely the spheres of municipal finance. Further research should be aimed at identifying additional reserves for strengthening the financial autonomy of municipalities. The expected results of the work include improving the financial situation of the population, optimising the budget system and leveling the level of development of municipalities. The importance of the proposed solution for balanced regional development and improving the quality of life of citizens is emphasised.
Overview of retail investment instruments of the Russian economy
Authors: Kosov M. E.
Published: November 2024

Features of the current stage of development of Russia increase the relevance of studying problems associated with the expansion of internal sources of financing economic growth, one of which may be citizens’ savings. To attract private capital more widely, the national financial system can and should provide a large range of tools for private investors that meet the needs of citizens in terms of profitability and safety of funds. The paper has considered the key tools of retail investment, which are currently widely used in domestic practice. Alternative ways of private investment have also been explored. They can be applied depending on the needs of specific actors, market participants, or citizens. The development of a line of instruments for the retail investment – deposits, long-term individual investment accounts, products of research and production associations, insurance products, etc., their availability is one of the conditions for the effective functioning of the domestic financial market and, as a consequence, the Russian economy as a whole. The analysis of the essence, trends, opportunities, and risks of the retail investment instruments will allow us to assess the effectiveness of the activities of financial regulators in this area and identify promising and appropriate areas for its improvement.
Modern conditions for reproduction of the educational potential of the Russian workforce
Authors: Komarova O. A.
Published: November 2024

The relevance of the research is related to the need to substantiate the specifics of reproduction of the educational potential of workforce as a key resource that ensures generation of new knowledge, its successful implementation into practice, and innovative development of domestic enterprises. The purpose of the article is to identify and analyse modern conditions for the reproduction of the educational potential of the workforce. The research methodology is based on the use of an integrated and systematic approach to determining them, comparative and statistical methods of analysis. As conditions for the formation of the educational potential in the post-industrial era, the article considers: demographic conditions, globalisation, formation of a unified information space, and digitalisation of the economy, increasing demand for skilled labour, accelerated development of the service sector, and increase in labour migration. The results of the analysis show that in Russia, the reproduction of the educational potential is hampered as a result of the demographic crisis manifested in the continuation of the trend towards natural population decline and an increase in the number of people of retirement age; increase in the scale of external migration of skilled labour; average level of Internet accessibility to the population, and, as a result, insufficient formation of its digital skills. Attention is focused on the growing need of the national economy for personnel with a high educational and qualification level, digital skills, and information culture due to the formation of a unified information space and digitalisation of the economy, accelerated development of the service sector, globalisation, and the increasing role of universities in shaping the general culture of the population. The prospects for further research are to develop an organisational and economic mechanism for reproducing the educational potential of the workforce.