bluuebunny/crossref_metadata_2025 huggingface dataset:
STRATEGI KOMUNIKASI MARKETING PUBLIC RELATIONS DALAM MEMBERIKAN PELAYANAN BAGI KONSUMEN (STUDI PADA CUSTOMER SERVICE PT RATU HOTEL BIDAKARA SERANG BANTEN
Authors: Tri Hapsari H.N. Lintang , Yuniarti Tatik
Published: September 2024

Ratu Hotel Bidakara is the newest 4 star hotel with  MICE (Meeting, Incentive, Convension,&  Exhibition)  category  in  Serang  city,  Banten  Province.  As  a  strategy  to  survive  in competition similar business in Serang City, Ratu Hotel Bidakara takes one step through the sinergy role of Public Relations and Marketing Public Relations in customer service.This study examines more about the role and effort of Marketing Public Relations as a customer service of Ratu Hotel Bidakara to improve service to the customers. The purpose of this study is to analyze the communication strategy and service system, as well as the efforts of Ratu Hotel  Bidakara  in  empowering  all  their  customer  service  officers.  Then  analyzed  the difference made to the general service and VIP guests and analyze coorporate images. This study used descriptive qualitative method, researcher explores the role and communication strategic is done by Marketing Public Relations as a customer service. Information obtained through  observation  and  depth  interviews  with  informants.  The  result  concluded  that Marketing Public Relations activities in Ratu Hotel Bidakara who perform three functions in accordance with the Ltyle theory (1996) used. First, the pre-transaction activities act as a Communication Technician, served as Deskman (providing information about products and services of the hotel). Second, in-transaction activity act as a receptionist and also as an Expert Prescriber (expert advisor), who performed the role of Customer Relations Officer (to maintain good relations with customers). Third, post-transaction activities act as a Communication Facilitator, Marketing Public Relations served as a communicator (a channel of communication between consumers and firms in response to consumer complaints)
REPRESENTASI KELAS PEKERJA PADA IKLAN TELEVISI PT JAMSOSTEK (PERSERO) (Analisis Semiotika Iklan Televisi PT Jamsostek (Persero) Versi “Manfaat”)
Authors: Wulansari Rina , . Saepudin
Published: September 2024

Marketers often use television ad as for promoting their products. Representation, free play of sign, certain meaning always present on television commercial ad. Commercial ad of PT Jamsostek (Persero) version “Manfaat” is one of the commercial ad the representation. Commercial ad of PT Jamsostek (Persero) version “Manfaat” present representation of the working class. Purpose of this research is to know representation of the working class, sign, and certain meaning on television commercial ad PT Jamsostek (Persero) version “Manfaat”.  Method  of  this  research  is  descriptive  qualitative  research  with  Roland Barthes’s semiotic analysis approach. As a descriptive research, this research is only explain situation or discourse and it is not to in relationship, or do not to examine of hypothesis or to make a prediction. Analysis of data the researcher use is Roland Barthes’s semiotic approach which include signifier a meaningful of sound or meaningful scribbles, signified is a representation of mental or concept  of something from signifier, denotation, and connotation. The signs on television commercial ad PT Jamsostek (Persero) version “Manfaat” oral, writing, and visual signs. The meaning of signs on this is the certain meaning of denotation and connotation. This commercial uses the denotation of meaning because it is want to know to the public in transparancy about the program as well as the advantage offered. This ad represents two class of labour, there are high class and low class
Ngayah: Communication Behaviour of Balinese Diaspora Jakarta
Authors: Utami Gusti Ayu Jayanti Oka , Dimyati Dindin
Published: September 2024

Pura Dalem Purnajati Tanjung Puri is one of Hindu temples located in Jakarta where Balinesepeople can observe and perform worship. However, in practice, Pura Dalem Purnajati TanjungPuri is also used as a place to observe traditional ceremonies such as Ngayah. Ngayah is a traditionconducted as a form of mutual assistance. The present study aimed to analyse the communicationbehaviour of Balinese diaspora in Jakarta for performing Ngayah. The present study usesqualitative method by conducting ethnography approach. Data was collected through observation,in-depth interview, and documentary study. The results show that Balinese diaspora in Jakartasimplified their tradition, including Ngayah tradition in Piodalan ceremony, where it can serve ascommunicative situation, communicative events, and communicative acts.Keywords: Balinese diaspora, Ngayah, culture, ethnography of communication
Makna Warrior bagi penggiat Ketofastosis Lifestyle
Authors: Primasari Winda , Yusup Heri
Published: September 2024

Ketofastosis Indonesia (KFI) adalah sebuah komunitas yang mengusung pola hidup sehat dan berkembang pesat. Salah satu keunikan dari KFI adalah sebutan warrior bagi para penggiat Ketofastosis Lifestyle. Penelitian ini bertujuan untuk mengetahui makna dari istilah warrior bagi para penggiat ketofastosis lifestyle yang tergabung di dalam grup Whatsapp. Penelitian ini menggunakan pendekatan kualitatif dengan metode pengambilan data melalui wawancara mendalam secara langsung dan melalui Whatsapp serta pengamatan interaksi yang terjadi di dalam grup Whatsapp. Hasil penelitian menunjukkan bahwa terdapat dua kategori warrior yang membedakan posisi atau kedudukan seorang penggiat ketofastosis lifestyle di dalam komunitas. Adapun kedua kategori tersebut adalah warrior pemula dan warrior mentor. Pembedaan kedua kategori didapat berdasarkan orientasi tujuan, pola interaksi dan significant others.
KOMUNIKASI INTERNAL HUMAS PT PERTAMINA (PERSERO) DALAM MEDIA ENERGIA WEEKLY
Authors: . Choerunnisa , Yuniarti Tatik
Published: September 2024

This study aims to analyze the internal communication is done by Public Relations of PT Pertamina (Persero) in Energia Weekly Media related efforts to form the image of the company. As we know that the internal media to help public relations convey the message from  company’s  management  to  the  workers.  The  method  used  by  the  author  in  this research was descriptive qualitative research design. Data collection method used is in- depth interviews and literature study / literature. Results of this study explain that the Public Relations of PT Pertamina (Persero) is under the Corporate Secretary, who runs the internal communication within Energia Weekly Media is Public Relations in Media Pertamina is located in the Corporate Communications Division. In conducting its internal communications  within  Energia  Weekly  Media,  Public  Relations  of  PT  Pertamina (Persero) has policies and operational procedures so that the message delivered in the Media  Weekly  Energia  well  received  by  workers  at  Pertamina.  Authors  came  to  the conclusion from this study is that internal communication activities conducted by Public Relations of PT Pertamina (Persero) is implemented affectively and fairly good. It can be seen from the use of any appropriate media for internal communications workers can apply corporate values in shaping a positive image of Pertamina.
ANALISIS FRAMING BERITA PEMILIHAN UMUM PRESIDEN (PILPRES) 2014 PADA HARIAN UMUM SUARA PEMBARUAN (Studi Analisis Framing Zhongdan Pan dan Gerald M. Kosicki di Rubrik Laporan Utama Periode Mei-Juli 2014)
Authors: Saputri Christina Sandra N. , Asmara D.A Yudha
Published: September 2024

This study , to see news framing presidential election ( Election) 2014 Daily Voice Reform especially , in the main report rubric period from May to July 2014. News 2014 presidential election , is the most interesting news for the media and the public because of public interest . At election time , almost the entire media displays this news as hedline one Voice Daily Updates.This study , using descriptive qualitative method with the theory of framing analysis models Zhongdan Pan and Gerald M. Kosicki .
This theory is used to analyze the 2014 presidential election reporting period from May to July in the main report section .The results of this study indicate that the news framing the 2014 presidential elections conducted by the Daily Voice Reform seen from the figure put forward the issue of its issue number 2 presidential candidate Joko Widodo ( Jokowi ) than the presidential candidate number 1 is Prabowo . Seen from the news headlines presented in the main report
PENGARUH BAURAN PEMASARAN TERHADAP KEPUTUSAN KONSUMEN DALAM MEMBELI DI HEMA RESTO KEMANG PRATAMA BEKASI
Authors: Mirantika Sefti Dwi , Khadijah Siti
Published: September 2024

Marketing communication strategies are important guidelines to introduce, give informations and market products in a company that can not be separated from the role marketing mix as the core of a marketing system. It takes some diligence and foresight to know what consumers desire for in a restaurant, such as HEMA Resto Dutch restaurant. As a result, HEMA should be able to attract consumers' attention from the product, price, place and promotion.
This study aims to analyze the effect of the implementation of the marketing mix including product policy, price, place and promotion of consumer buying decisions in the HEMA restaurant. Research conduced in June-July 2012 at the HEMA Resto Kemang Pratama, methods used is case study. Method of determining the location Judgesment Sampling is based on several criteria, namely: Consumer HEMA Resto Kemang Pratama, 17-50 years of age or older, was selected because of HEMA Resto Kemang Bekasi. Determination of Sampling Methods using the Slovin formula, where the consumer is taken as the respondents were 100 people, the primary obtained data questionnaires and interviews with respondents and restaurant marketing manager.
The results of multiple linear regression analysis by simultaneously obtained Fhitung> F  table is  41.544> 2.70  means  the  marketing  mix  variables  simultaneously influencing consumer buying decisions. Of partial regression test for the product (X1) is obtained 9.072 t count <t chart 1.98498. Price (X2) t count 4.975  t table 1.98498. Promotion (X4) t count 0.739 <t chart 1.98498. partial product pricing policy and influence buying decisions, while place and promotion policies have no effect on consumer buying decisions
STRATEGI KOMUNIKASI INSTRUKSIONAL GURU BAHASA INDONESIA DENGAN SISWA DI SMP AMAL MULIA KLAPANUNGGAL BOGOR
Authors: Gabena Siregar Nofita Asyiah , Primasari Winda
Published: September 2024

SMP Amal Mulia is a private junior high school standing in the Klapanuggal in 1999. The school is located in the residential neighborhood residents sunda, many students SMP amal mulia are used to communicating with sundanese therefore Indonesian teacher uses instructional communication strategies to increase students' language skills SMP Amal Mulia.
This study reviews Instructional Communication Strategy with Student Teachers in SMP Amal Mulia in Klapanunggal Bogor. The purpose of this study was to analyze the instructional communication strategies used by Indonesian languange   teacher to improve students' language skills SMP. Besides analyzing instructional communication strategy, the authors also analyzes the process of message processing, the use of message communication, the use of instructional media and communication techniques and tactics used by Indonesian teacher. This research method is descriptive qualitative, the author explores instructional communication strategies used by Indonesian teacher. Information obtained through observation and depth interviews with key informants and informants.
The results of this study illustrate that the instructional communication strategies used by Indonesian teacher is the gift of communication strategies (rewarding) and punishment (punishing). The processing of messages that are used to support the communication is processing   messages   expressive,   conventional,   and   rhetorical.   Media   is   often   used instructional tapes, videos, and training in the language lab. Instructional communication method used is the method of lecture, discussion and question and answer. Techniques and tactics used are small grouping technique and tactical use of communications with elements of humor. This strategy is used because it has received greater attention than other instructional communication strategy
MODIFICATIONS OF CONVENTIONAL CONCEPTUAL METAPHORS IN THREE INSURANCE ADVERTISEMENTS
Authors: Harahap Aris Masruri , Hermanto Lambok
Published: September 2024

Makalah ini membahas bagaimana metafora konseptual yang bersifat konvensional dimodifikasi dalam tiga iklan asuransi. Pendekatan yang digunakan yaitu kajian linguistik kognitif berdasarkan teori Lakoff dan Johnson (1980) dan Kövecses (2010). Tujuan dari penelitian ini adalah untuk mengungkap tujuan komunikatif dalam suatu periklanan yang menggunakan gaya bahasa tertentu, dalam hal ini metafora konseptual.  Selanjutnya, studi ini akan menunjukkan sampai sejauh mana keefektifan dan keefesienan metafora konseptual yang dimodifikasi tersebut. Hasil dari kajian ini memperlihatkan bahwa tiga iklan asuransi yang menjadi objek penelitian menggunakan versi modifikasi dari metafora konseptual yang konvensional melalui cara ‘extending’ ‘elaboration’ dan/atau ‘combining’.Dengan cara-cara tersebut, iklan-iklan asuransi ini sepertinya memiliki tujuan untuk menanamkan ide dramatis dalam benak pembaca sehingga mereka menjadi tertarik untuk membeli produknya
PENGGUNAAN MEDIA SOSIAL TWITTER DALAM PEMBENTUKAN DIMENSI EKUITAS MEREK L-MEN
Authors: Darmawati Widya , . Saepudin
Published: September 2024

Nowadays, social media is used for branding and it is not only being trend, but a requirement to keep in touch with the audiences. It is caused by the number of social media user which getting increase day per day. Social media could be an alternative media for branding and making stronger brand equity. L-Men also uses Twitter to inform and interact with the audiences. This research discuss the framework  of L - Men while using Twitter and what kind of brand equity that constructed on its account. This research used qualitative method. It found that L-Men has its own goal, objective, strategies, and tactics on using Twitter  for  branding.  Furthermore,  brand  awareness  dimension  has  been  constructed  on  using  its Twitter. But, the other dimensions –such as brand association, perceived quality, and brand loyality- have not been constructed as well as brand awareness dimension
Analisis Kecenderungan Pemberitaan Kampanye Calon Presiden 2019 di Antaranews.com
Authors: Rukhwandir Andam , Yuniarti Tatik
Published: September 2024

This study discusses the balance of the 2019 presidential election campaign coverage on Antaranews.com. This research uses a quantitative approach with descriptive content analysis method which is carried out through coding techniques on the news that has been determined as a sample in the study. The research was conducted by coding news samples through Westerstahl's objectivity theory. The objectivity of news can be measured through this theory, which has two dimensions, namely, factuality and impartiality. Coding is done by analyzing the sentences in the news through these dimensions which are divided into several indicators. The results of the study found that there was a tendency for the 2019 presidential candidates to report on Antaranews.com. The news on the presidential candidates on Antaranews.com tended to be more towards Joko Widodo. This is evident in Jokowi's reporting, which tends to show more positive opinions and a larger portion of the coverage.
Grammar to Vlog : Meaningful and authentic language practice for 21st century ESL learners
Authors: Prihhartini Sya'baningrum
Published: September 2024

This study investigated the effectiveness of using Youtube to practice grammar. As Youtube vlogging has become the most current internet phenomena and one of the most sought career choices by today’s young generation, it is one of the most suitable platforms, both to learn and to practice the target language. In this study, 10 first-year university students from an intact-required class participated. The learners were given a task to make a video of them cooking, where they put the targeted grammatical items into use, and then upload it onto Youtube. Videos taken from the learners’ Youtube channels were collected, and qualitative method was utilized to see what strategies the learners employed to bridge the gap between the intended meaning and the lack of grammatical or word knowledge. The findings showed that the learners employed substitution, nonverbal language, and switching to L1 form pattern to overcome the language barrier they encountered during the communicative task. The result of this study shows that Youtube can be used as a meaningful and effective platform to practice grammatical structure, as the learners utilize their skills and strategies for an authentic language use.
THE ROLE OF SOCIAL MEDIA IN BUILDING A BRAND IMAGE TO MAINTAIN A CORPORATE IMAGE ON TPA (THIRD PARTY ASSITANCE) COMPANIES
Authors: Baskoro Arga
Published: September 2024

The increasing number of social media users has presented new media for public relations communication. This is then used by companies to maximize social media to provide information about products or services. This study aims to determine the role of social media in building brand image and its role in maintaining corporate image. The concept which uses in this study are the Social Media network, MPR, Cyber PR, Brand Image, and Corporate Image. The research objects are social media of TPA (Third Party Assistance) Companies such as AAI Indonesia, Fullerton, Admedika and Owlexa. This study uses post positivist paradigm, a qualitative approach and is descriptive in nature. In this study it was found that social media is not instrumental tools in building their brand image and also not play a role in maintaining the corporate image.
SELF-CONCEPT AND SELF DISCLOSURE OF TEENAGER BROKEN HOME
Authors: Khasanah Iswatun , Katili Kartini Rosmalah Dewi
Published: September 2024

In the condition of broken home family especially for a teenager there are many concepts that are classified negatively with their own causative factors one of them is having a family that is not harmonious. During this transition from childhood to adulthood that the concept began to form. Self- concept is our own beliefs and self-perception. and a teenager's ability to communicate interpersonally also affects self-opening. The purpose of this research is to find out the picture of self- concept and self disclosure of broken home adolescents. The method used was qualitatively descriptive with in-depth interviews of six broken home teens with different foster patterns. The results showed that teenagers from broken home families had positive and negative self-concepts. Positive self-concepts have traits: feeling disliked by others, feeling hopeless and doing negative things. Negative self-concepts have traits: tend to feel disliked by others, experience barriers to interacting with their social environment, feel hopeless/negative, and unable to control themselves in the midst of conflict. While in self disclosure broken home teenagers tend to have an open and closed attitude. Characteristics of self disclosure open attitude include: assessing messages objectively and being able to distinguish easily and see nuances. While the characteristics of a closed attitude include: assessing messages based on personal motives, more on the source of the message than the content of the message, and teaching information about other people's beliefs from the source itself. For further research can explore the social influence on the formation of broken home adolescent self concept using the theory of social communication psychology.
DENOTATION AND CONNOTATION IN LONDON’S WILLIAM BLAKE
Authors: Nuryadi Nuryadi
Published: September 2024

The industrial revolution had brought negative impact on society in England. The first is economic inequality and the second is the moral damage of society. The bad impact is described by William Blake in his poem entitled London. This study aims to find the description through the meaning of denotation and connotation. The poem was written in the era of romance. In this period, literary works were dominated by elements such as imagination, freedom of expression, and idealism. The research method is descriptive qualitative. This study uses a semantic approach, especially the meaning of denotation and connotation as well as the theory of English literature and culture. Based on the results of data analysis, five words with denotative and connotative meanings are found. Those words are chartered, manacles, blackning church, harlots and blasts. The connotative meanings of these five words are used to describe the economic inequality and  the moral damage of society as a result of the industrial revolution. Roads and rivers are controlled by factories, freedom of speech is shackled, God's voice is no longer heard, women experience moral decadence and people live terrible fear because of the high crime rate.
The Effect of Metformin on Survival in Patients with Non-Small Cell Lung Cancer
Authors: Özdöver Ali Caner , Fidan Evren , Dişli Şafak , Rakıcı Nejla , Kazaz Seher Nazlı
Published: September 2024

Aim: Lung cancer is the most common cause of cancer- related deaths in the world. Diabetes mellitus (DM) can be seen frequently in the lung cancer patient group as well as in the normal population. Metformin is one of the most commonly used biguanide drugs in the treatment of DM. Studies conducted in patients with different types of cancer, such as breast, liver, and prostate, have shown that metformin use may contribute to survival. The aim of the study is to evaluate the effect of metformin on survival in patients with non-small cell lung cancer (NSCLC).
Matherial and Methods: In this study, 85 patients diagnosed with non-small cell lung cancer and concurrent type 2 DM retrospectively were analyzed, and the last follow-up date was 31.11.2020. Neutrophil/lymphocyte ratio (NLR) of the patients was calculated. Alkaline phosphatase (ALP), lactate dehydrogenase (LDH), carcinoembryonic antigen (CEA) values and their contribution to survival were examined.
Results: The 1, 3, and 5-year overall survival rates for all patients were 76.0%, 46.5%, and 34.3%, respectively, and the median OS was 64.1 (95% CI: 44.7-83.5). Lymph node (LN) positivity, liver metastasis, and death rates were less common in the patient group receiving metformin. Overall survival (OS) results and determined survival rates were worse in the non-metformin patient group.
Conclusion: Metformin usage and the control of hyperinsulinemia and hyperglycemia may contribute to survival rates. Larger and prospective studies are needed to determine the effect of metformin which is used for glycemic control and insülin resistance, in NSCLC patients' survival.
Kanser Hastalarının Bakım Vericilerinin Bakım Yükü ve Bakım Vermeye Yönelik Gösterdikleri Tepkilerin Belirleyicileri
Authors: Pehlivan Sarıbudak Tugba , İşcan Sanem , Güner Perihan
Published: September 2024

Amaç: Bu çalışmanın amacı, kanser hastalarına bakım veren primer bakım vericilerin subjektif bakım yüklerini ve bakım vermeye yönelik gösterdikleri tepkileri belirlemektir.
Gereç ve Yöntemler: Tanımlayıcı tipteki araştırma bir özel üniversite hastanesinin, ayaktan kemoterapi ünitesi ve yatan hasta servisinde Nisan 2017-2018 tarihleri arasında kanser tedavisi gören hastaların 140 primer bakım vericisi ile gerçekleştirilmiştir. Verilerin toplanmasında hasta ve hasta yakını bilgi formu, bakım verenin stres indeksi (BSI) ve aile bireyinize yardımcı olmaya gösterdiğiniz tepkiler (ABYT) ölçeği kullanılmıştır. Bağımlı değişkenleri açıklayan belirleyicileri ortaya çıkarmak için çoklu aşamalı doğrusal regresyon analizi yapılmıştır.
Bulgular: Katılımcıların bakım verenin stres indeksi puan ortalamaları 4,41 (SS=3,77) ve bakım vermeye yönelik gösterdikleri tepkiler ölçeği puan ortalamaları 23,15 (SS=12,12)’dir. Bakımda aldığı yardımı yeterli bulma durumu, hastanın çalışma durumu ve günlük yaşam aktivitelerini yerine getirebilme durumu bakım verenin stres indeksinin belirleyicileri olarak bulunmuştur. Bakım vericinin bakımda aldığı yardımı yeterli bulma durumu ve hastanın günlük yaşam aktivitelerini yerine getirebilme durumu bakım vermeye yönelik gösterdikleri tepkilerin belirleyicileri olarak bulunmuştur.
Sonuç: Çalışmamızda, bakım vericilerin subjektif bakım yüklerinin ve bakım vermeye gösterdikleri olumsuz tepkilerin düşük düzeyde olduğu bulunmuştur. Sonuç değişkenlerini açıklayan en önemli belirleyicilerin bakım konusunda yardım alma ve bakım verilen hastanın günlük yaşam aktivitelerinde bağımlı olup olmama durumu olduğu saptanmıştır. Bağımlı hastalara bakım veren bireylerin bakım yükünün daha fazla olması bakımından risk altında olması ve bu gruba yönelik müdahalelerin planlanması önerilmektedir. Ayrıca, hemşireler tarafından bakım verenlere bu süreçte aldıkları yardımın öneminin aktarılması ve desteklenmesi önemlidir.
Fizyoterapi ve Rehabilitasyon Bölümü Öğrencilerinin Afet Konusundaki Bilgi Tutum ve Davranışları: Tanımlayıcı Pilot Araştırma
Authors: Özmen Tarık , Contarlı Nurcan
Published: September 2024

Amaç: Bu çalışma, Fizyoterapi ve Rehabilitasyon Bölümü öğrencilerinin afet konusundaki bilgi tutum ve davranışlarını değerlendirmek amacıyla gerçekleştirildi.
Gereç ve Yöntemler: Kesitsel tanımlayıcı nitelikte olan bu çalışmaya Fizyoterapi ve Rehabilitasyon Bölümü’nde öğrenim gören 507 öğrenci (327 kadın, 180 erkek) dâhil edildi. Sosyodemografik özellikler, afet konusunda bazı bilgiler ve Genel Afet Hazırlık İnanç Ölçeği (GAHİÖ) "Google forms" aracı ile sorgulandı.
Bulgular: Çalışmaya katılan öğrencilerden %42,8’inin afet yaşadığı ve en sık yaşadıkları afet türünün %51,1 oranı ile deprem olduğu görüldü. Öğrencilerin %59,6’sının ikamet ettikleri yerin afet riski hakkında bilgi sahibi olduğu, %44,6’sının afetler konusunda eğitim aldığı ve %71,8’inin daha önce bir afet tatbikatına katıldığı tespit edildi. Öğrencilerin GAHİÖ puan ortanca değeri 113 (78-148) olarak tespit edildi. Öğrencilerin GAHİÖ puanları; kadın öğrencilerin erkeklere göre (p
A Scientometric Analysis of Mechanical Cardiopulmonary Resuscitiation Device Publications
Authors: Ağaçkıran İlter , Günay Serkan , Ağaçkıran Merve , Demir Mehmet Cihat , Yürekli Ümit Can , Komut Seval , Öztürk Ahmet , Erenler Ali Kemal
Published: September 2024

Aim: Today, the use of automatic chest compression devices is increasing. The aim of this study is to identify popular publications about chest compression devices, save time for researchers, and summarize the important points of chest compression devices using the scientometric analysis method.
Material and Methods: All data were collected using the Web of Science Core Collection between July 1-8, 2023. Articles related to the topic were selected using the keywords "automated chest compression device" or "mechanical chest compression device". All articles in the database were manually scanned and analyzed. The distribution of relevant articles in the database was analysed according to scientific journals. Global research productivity, international collaborations, and research themes were analyzed using the scientometric method.
Results: A total of 589 articles were identified in the WoS. Out of these, 439 (74.407%) were original articles, followed by 63 (10.678%) review articles and 30 (5.085%) editorial materials. When examining the distribution of research articles by country, the United States (US) topped the list with 171 articles, followed by Germany (n=77). Although the UK ranked third in terms of the number of publications with 53 articles, it ranked first in terms of the number of citations. (n=3465). An assessment of the top 20 publishing journals revealed that the Resuscitation Journal led in terms of publication count (n=133), citation count (n=5906), and average citations per publication (n=44.41).
Conclusion: Our bibliometric study analyzed 589 articles on mechanical cardiopulmonary resuscitation. This can help researchers identify trending topics and areas of interest more quickly. More research is needed to fully understand the effectiveness and best tools for saving lives in emergency situations.
Pemanfaatan Teknologi Informasi untuk Promosi Pariwisata Melalui Media Sosial di Dinas Pariwisata Kabupaten Ngada
Authors: Mandala Diana Romauli Tanggo Ledeng , Fahlevvi Mohammad Rezza
Published: September 2024

Penelitian ini berfokus pada permasalahan pemanfaatan teknologi informasi terutama media sosial dalam hal peningkatan promosi pariwisata di Kabupaten Ngada. Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis faktor serta upaya yang dapat dilakukan oleh pemerintah daerah untuk menghadapi era zaman sekarang dalam pemanfaatan teknologi informasi dalam membantu mempromosikan potensi daerah khususnya bidang pariwisata yang menjadi unggulan dari Kabupaten Ngada. Penelitian yang digunakan adalah metode deskriptif kualitatif dengan pendekatan induktif. Teknik pengumpulan data mencakup wawancara, observasi, dan dokumentasi. Analisis data yang dilakukan melalui reduksi data, penyajian data, serta penarikan kesimpulan menggunakan teori e-government Indrajit yang membuat penelitian ini berbeda dengan penelitian lainnya, teori tersebut mencakup 3 Dimensi yaitu support, capacity, dan value. Temuan yang diperoleh dalam penelitian ini yaitu masih ditemukan beberapa kendala seperti masih kurangnya infrastruktur jaringan yang mencukupi untuk daerah yang memiliki tempat wisata, masih kurangnya sumber daya manusia yang mengoperasikannya, dan yang ketiga adalah anggaran. Kesimpulan yang dapat diambil dari penelitian ini menunjukan adanya upaya yang telah dilakukan oleh pemerintah daerah terlebih lagi dari Dinas Pariwisata untuk mempromosikan pariwisata namun dalam sejalannya waktu pemanfaatan teknologi informasi tersebut belum terlihat maksimal, sehingga tetap perlu adanya peningkatan baik itu dari SDM, infrstruktur, dan juga anggaran.
BİR ÜNİVERSİTENİN DİŞ HEKİMLİĞİ FAKÜLTESİ’NDE VERİLEN TEMEL İLKYARDIM DERSİNİN ETKİNLİĞİ
Authors: Öğüt Düzen Kerime , Sezer Balcı Ayşe
Published: September 2024

Bu araştırmanın amacı, bir üniversitenin Diş Hekimliği Fakültesi’nde verilen temel ilkyardım dersinin etkinliğini değerlendirmektir. Bu araştırma tek gruplu ön test–son test tasarım ile yarı deneysel olarak yapıldı. Araştırmanın evrenini 2023-2024 Eğitim Öğretim Döneminde bir üniversitenin Diş Hekimliği Fakültesinde Temel İlkyardım dersini alan öğrenciler (N=67) oluşturdu. Veri toplama aracı olarak ‘Sosyo-Demografik Form’ ve araştırmacılar tarafından geliştirilmiş olan ‘Temel İlkyardım Bilgisi Soru Formu’ kullanıldı. Çalışmada tanımlayıcı istatistikler için (sayı, yüzde, ortalama, standart sapma), eşleştirilmiş gruplarda ki kare testi kullanıldı. Araştırmaya katılan öğrencilerin yaş ortalaması 18.98±1.46, %56.7'si kadın ve 65 tanesi (%97) bekardı. Araştırmada eğitim sonrası dönemde, öğrencilerin ilkyardıma ilişkin sorulara verdiği doğru yanıt oranlarının arttığı görüldü. Doğru yanıt oranında en yüksek artışların kanamalar, bilinç kaybı bozuklukları, kırıklar, yanıklar ve burkulmalar ile ilgili sorulara verilen cevaplarda olduğu görüldü (p
Effect of pH and hydroxyapatite-like layer formation on the antibacterial properties of borophosphate bioactive glass incorporated poly(methyl methacrylate) bone cement
Authors: Hageman Kara A. , Blatt Rebekah L. , Kuenne William A. , Brow Richard K. , McIff Terence E.
Published: September 2024

Infection is a leading cause of total joint arthroplasty failure. Current preventative measures incorporate antibiotics into the poly (methyl methacrylate) (PMMA) bone cement that anchors the implant into the natural bone. With bacterial resistance to antibiotics on the rise, the development of alternative antibacterial materials is crucial to mitigate infection. Borate bioactive glass, 13–93-B3, has been studied previously for use in orthopedic applications due to its ability to be incorporated into bone cements and other scaffolds, convert into hydroxyapatite (HA)-like layer, and enhance the osseointegration and antibacterial properties of the material. The purpose of this study is to better understand how glass composition and change in surrounding pH effects the composite’s antibacterial characteristics by comparing the incorporation of 30% wt/wt 13–93-B3 glass and pH neutral borophosphate bioactive glass into PMMA bone cement. We also aim to elucidate how HA-like layer formation on the cement’s surface may affect bacterial adhesion. These studies showed that 13–93-B3 incorporated cements had significant reduction of bacterial growth surrounding the composite beyond 24 h of exposure when compared to a neutral borate bioactive glass incorporated cement (p < 0.01) and cement only (p < 0.0001). Additionally, through soaking cement composites in simulated body fluid and then exposing them to a bioluminescent strand of staphylococcus aureus, we found that the presence of a HA-like layer on the 13–93-B3 or pH neutral glass incorporated cement disks resulted in an increase in bacterial attachment on the composite cement’s surface, where p < 0.001, and p < 0.05 respectively. Overall, our studies demonstrated that borate bioactive glass incorporated PMMA bone cement has innate antimicrobial properties that make it a promising material to prevent infection in total joint arthroplasties.
Factors to consider before choosing EV labeling method for fluorescence-based techniques
Authors: Dlugolecka Magdalena , Czystowska-Kuzmicz Malgorzata
Published: September 2024

A well-designed fluorescence-based analysis of extracellular vesicles (EV) can provide insights into the size, morphology, and biological function of EVs, which can be used in medical applications. Fluorescent nanoparticle tracking analysis with appropriate controls can provide reliable data for size and concentration measurements, while nanoscale flow cytometry is the most appropriate tool for characterizing molecular cargoes. Label selection is a crucial element in all fluorescence methods. The most comprehensive data can be obtained if several labeling approaches for a given marker are used, as they would provide complementary information about EV populations and interactions with the cells. In all EV-related experiments, the influence of lipoproteins and protein corona on the results should be considered. By reviewing and considering all the factors affecting EV labeling methods used in fluorescence-based techniques, we can assert that the data will provide as accurate as possible information about true EV biology and offer precise, clinically applicable information for future EV-based diagnostic or therapeutic applications.
RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae
Authors: Qiu Yichuan , Xiang Li , Yin Ming , Fang Chengju , Dai Xiaoyi , Zhang Luhua , Li Ying
Published: September 2024

Hypervirulent K. pneumoniae (hvKp) have emerged as clinically important pathogens, posing a serious threat to human health. RfaH, a transcriptional elongation factor, has been regarded as implicated in facilitating the transcription of long virulence operons in certain bacterial species. In K. pneumoniae, RfaH plays a vital role in promoting CPS synthesis and hypermucoviscosity, as well as mediating bacterial fitness during lung infection. In this study, we aim to conduct a systematic investigation of the roles of rfaH in the survival, dissemination, and colonization of hvKp through in vitro and in vivo assays. We found that bacterial cells and colonies displayed capsule -deficient phenotypes subsequent to the deletion of rfaH in K. pneumoniae NTUH-K2044. We confirmed that rfaH is required for the synthesis of capsule and lipopolysaccharide (LPS) by positively regulating the expression of CPS and LPS gene clusters. We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. We further demonstrated that the absence of rfaH was associated with slower bacterial growth under conditions of low nutrition or iron limitation. ΔrfaH displayed reduced survival rates in the presence of human serum. Besides, the engulfment of the ΔrfaH mutant was significantly higher than that of NTUH-K2044 by macrophages in vivo, indicating an indispensable role of RfaH in the phagocytosis resistance of hvKp in mice. Both mouse intranasal and intraperitoneal infection models revealed a higher bacterial clearance rate of ΔrfaH in lungs, livers, and spleens of mice compared to its wild type, suggesting an important role of RfaH in the bacterial survival, dissemination, and colonization of hvKp in vivo. Histopathological results supported that RfaH contributes to the pathogenicity of hvKp in mice. In conclusion, our study demonstrates crucial roles of RfaH in the survival, colonization and full virulence of hvKp, which provides several implications for the development of RfaH as an antibacterial target.
A comparative study of femoral artery and combined femoral and axillary artery cannulation in veno-arterial extracorporeal membrane oxygenation patients
Authors: Jin Na , Pang Xin , Song Shiyang , Zheng Jin , Liu Zhimeng , Gu Tianxiang , Yu Yang
Published: September 2024

Objective

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a critical support technique for cardiac surgery patients. This study compares the outcomes of femoral artery cannulation vs. combined femoral and axillary artery cannulation in post-cardiotomy VA-ECMO patients. This study aimed to compare the clinical outcomes of critically ill patients post-cardiac surgery under VA-ECMO support using different cannulation strategies. Specifically, the focus was on the impact of femoral artery (FA) cannulation vs. combined femoral artery and axillary artery (FA+AA) cannulation on patient outcomes.

Methods

Through a retrospective analysis, we compared 51 adult patients who underwent cardiac surgery and received VA-ECMO support based on the cannulation strategy employed—FA cannulation in 27 cases vs. FA+AA cannulation in 24 cases.

Results

The FA+AA group showed significant advantages over the FA group in terms of the incidence of chronic renal failure (CRF) (37.50% vs. 14.81%, p = 0.045), preoperative blood filtration requirement (37.50% vs. 11.11%, p = 0.016), decreased platelet count (82.67 ± 44.95 vs. 147.33 ± 108.79, p = 0.014), and elevated creatinine (Cr) levels (151.80 ± 60.73 vs. 110.26 ± 57.99, p = 0.041), although the two groups had similar 30-day mortality rates (FA group 40.74%, FA+AA group 33.33%). These findings underscore that a combined approach may offer more effective hemodynamic support and better clinical outcomes when selecting an ECMO cannulation strategy.

Conclusion

Despite the FA+AA group patients presenting with more preoperative risk factors, this group has exhibited lower rates of complications and faster recovery during ECMO treatment. While there has been no significant difference in 30-day mortality rates between the two cannulation strategies, the FA+AA approach may be more effective in reducing complications and improving limb ischemia. These findings highlight the importance of individualized treatment strategies and meticulous monitoring in managing post-cardiac surgery ECMO patients.
Scaling up! Staff e-learning for a national take-home naloxone program
Authors: Ericson Øystein Bruun , Eide Desiree , Brendryen Håvar , Lobmaier Philipp , Clausen Thomas
Published: September 2024

Background

A staff e-learning course was developed to prepare for scaling up a national take-home naloxone (THN) program in Norway. The aims of the study were to (a) describe participant characteristics for those that completed a THN e-learning course, (b) compare opioid overdose knowledge scores before and after e-learning course completion, and (c) to explore subsequent THN distribution by those trained.

Methods

This was a quasi-experimental pre-test, post-test longitudinal cohort study of individuals completing a THN e-learning course from April 2021 to May 2022. Frequency analyses were performed for participant characteristics and subsequent naloxone distributions at 1-week and 1-month follow-up. The opioid overdose knowledge scale (OOKS) was used to measure pre-test-post-test knowledge among participants. Wilcoxon signed-rank test was performed for comparison between pre-test and post-test. Effect size was calculated using Cohen criteria.

Results

In total, 371 individuals were included in this study. Most were either nurses or social workers (n = 277, 75%). Participant knowledge increased by medium or large effect for all items measured. At 1-month follow-up, 15% reported naloxone distribution. During the study period, 94 naloxone kits were distributed. Major reasons for not distributing were “clients not interested”, “workplace not distributing” and “workplace in process of distributing”.

Conclusions

Our findings suggest that an e-learning course is equally effective in terms of knowledge transfer as an in-person classroom setting, and may provide engagement in terms of naloxone distribution. However, our findings also emphasize the importance of clear implementation routines, including support from central coordinators to optimize the implementation process.
Demonstrating the principal mechanism of action of medical devices intended for vaginal use on reconstructed human vaginal epithelium: the case of two hyaluronic acid-containing devices
Authors: Meloni Marisa , De Servi Barbara , Carriero Francesco , Simon O’Brien Emmanuelle , Houamel Dounia , Deruelle Philippe , Castagné Vincent
Published: September 2024

Regulation (EU) 2017/745 on medical devices (MDR) has significantly modified the rules to be adopted for MD qualifications and classification. New requirements require robust evidence on mechanisms of action (MoAs) that cannot be produced by existing common EU or ISO standards. Therefore, on a “case-by-case basis,” a new evidence-based non-clinical approach to MD qualification must be defined. In this study, an in vitro experimental approach is described to assess the physicochemical and mechanical MoA of two hyaluronic acid (HA)-based medical devices: Mucogyne® Gel and Mucogyne® Ovule for vaginal use. They both act as moisturizers and lubricants as well as a healing adjuvant by promoting the continued moisture of the vulvovaginal area. The MoA of these two products has been demonstrated by using a 3D reconstructed human vaginal epithelium (HVE) model in a homeostatic physiological state and in stressed conditions. Film forming and persistency properties were assessed on intact HVE tissues by caffeine permeation assay and Lucifer Yellow (LY) localization on HVE vertical sections. Healing properties were assessed on injured HVE tissues by trans-electrical epithelial resistance (TEER) measurements associated with histo-morphological analysis (H&E), and moisturizing efficacy was evaluated on HVE tissues cultured in dry conditions by histomorphological analysis (H&E) and aquaporin 3 (AQP3) expression and localization by immunohistochemistry (IHC). Using the same “dry” HVE model, the non-pharmacological action of the two products was addressed by CD44 (hyaluronic acid receptor) expression and localization. The results suggest that in vitro evaluations can provide robust results on a human-relevant experimental model for the intended use of the products and supports clinical data with mechanistic information which may not be achieved with in vivo studies but are particularly important for product qualification. The results also underline the specific relative efficacy of the mechanisms investigated for Mucogyne® Gel and Mucogyne® Ovule in line with their different formulation types (respectively, hydrophilic and lipophilic) that influence the action of the active ingredient HA. The present in vitro non-clinical evaluation of HVE combined with clinical investigation data obtained in women explain why Mucogyne MDs provide significant benefits in various physiological or pathological situations, including vaginal dryness and healing.
Impact of diverse aerobic exercise plans on glycemic control, lipid levels, and functional activity in stroke patients with type 2 diabetes mellitus
Authors: Chen Kangcheng , Wang Yulong , Li Dongxia , Li Jun , Huang Yong , Huang Meiling , Ma Haifeng
Published: September 2024

Aims

This study aimed to assess the effects of Low-to-Moderate Intensity Continuous Training (LMICT), Moderate-Intensity Interval Training (MIIT), and Reduced-Exertion High-Intensity Training (REHIT) on blood glucose regulation, functional recovery, and lipid levels in individuals who have experienced a stroke and are diagnosed with Type 2 Diabetes Mellitus (T2DM).

Methods

Forty-two T2DM stroke patients were randomly allocated to four groups: LMICT, MIIT, REHIT, and a control group (CON). Participants continuously monitored their blood glucose levels throughout the intervention using continuous glucose monitoring (CGM) devices. The study comprised two exercise intervention cycles: the first lasting from Day 3 to Day 14 and the second from Day 15 to Day 28, with the initial two days serving as contrasting periods. Primary outcomes encompassed CGM-derived blood glucose measurements, the Barthel Index (BI), Fugl-Meyer Assessment lower-extremity subscale (FMA-LE), and alterations in triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c).

Results

Compared with the CON, the MIIT group showed significant improvements in mean glucose (MG), glucose standard deviation (SD), time above range (TAR), and time in range (TIR). The REHIT group exhibited significantly reduced time below range (TBR), glucose SD, and coefficient of variation (CV). Regarding lipid levels, although the REHIT group achieved a significant reduction in TG levels compared with the CON, the overall effects of LMICT, MIIT, and REHIT on lipid profiles were relatively modest. Concerning functional recovery, the REHIT group significantly improved the BI and FMA-LE.

Conclusion

Although the short-term quantitative impact of exercise on lipid levels may be limited, both REHIT and MIIT significantly improved glycemic management and reduced glucose variability in post-stroke patients with Type 2 Diabetes Mellitus. Additionally, REHIT notably enhanced functional recovery.