bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S1 from Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma
Authors: Wei Xiaomu , Calvo-Vidal M. Nieves , Chen Siwei , Wu Gang , Revuelta Maria V. , Sun Jian , Zhang Jinghui , Walsh Michael F. , Nichols Kim E. , Joseph Vijai , Snyder Carrie , Vachon Celine M. , McKay James D. , Wang Shu-Ping , Jayabalan David S. , Jacobs Lauren M. , Becirovic Dina , Waller Rosalie G. , Artomov Mykyta , Viale Agnes , Patel Jayeshkumar , Phillip Jude , Chen-Kiang Selina , Curtin Karen , Salama Mohamed , Atanackovic Djordje , Niesvizky Ruben , Landgren Ola , Slager Susan L. , Godley Lucy A. , Churpek Jane , Garber Judy E. , Anderson Kenneth C. , Daly Mark J. , Roeder Robert G. , Dumontet Charles , Lynch Henry T. , Mullighan Charles G. , Camp Nicola J. , Offit Kenneth , Klein Robert J. , Yu Haiyuan , Cerchietti Leandro , Lipkin Steven M.
Published: March 2023

Clinical characteristics of familial myeloma probands who were studied with germline whole exome sequencing.
Supplementary Figure S2 from Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Authors: Hiasa Masahiro , Okui Tatsuo , Allette Yohance M. , Ripsch Matthew S. , Sun-Wada Ge-Hong , Wakabayashi Hiroki , Roodman G. David , White Fletcher A. , Yoneda Toshiyuki
Published: March 2023

Contribution of TRPV1 to sprouting and activation of SN and MMBP in JJN3-injected mice.
Supplementary Table 1 from CD155T/TIGIT Signaling Regulates CD8+ T-cell Metabolism and Promotes Tumor Progression in Human Gastric Cancer
Authors: He Weiling , Zhang Hui , Han Fei , Chen Xinlin , Lin Run , Wang Wei , Qiu Haibo , Zhuang Zhenhong , Liao Qi , Zhang Weijing , Cai Qinbo , Cui Yongmei , Jiang Wenting , Wang Han , Ke Zunfu
Published: March 2023

Supplementary Table 1 shows clinicopathological characteristics of the patients studies in this project.
Supplementary Figure S4 from CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer
Authors: Alfaqih Mahmoud A. , Nelson Erik R. , Liu Wen , Safi Rachid , Jasper Jeffery S. , Macias Everardo , Geradts Joseph , Thompson J. Will , Dubois Laura G. , Freeman Michael R. , Chang Ching-yi , Chi Jen-Tsan , McDonnell Donald P. , Freedland Stephen J.
Published: March 2023

27HC inhibits the growth of androgen-sensitive and -insensitive PC cell lines
Supplement from RUNX1 Upregulation by Cytotoxic Drugs Promotes Apoptosis
Authors: Speidel Daniel , Wellbrock Jasmin , Abas Melissa
Published: March 2023

This file contains a schematic of mouse RUNX1 isoforms, data on RUNX1 upregulation in EL-4 cells as well as additional results elucidating the consequences of RUNX1 overexpression in Namalwa and Ba/F3 cells. This file also contains an additional paragraph of discussion related to the importance of post-translational modifications and related references.
Supplementary File 4 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers
Authors: Mundt Filip , Rajput Sandeep , Li Shunqiang , Ruggles Kelly V. , Mooradian Arshag D. , Mertins Philipp , Gillette Michael A. , Krug Karsten , Guo Zhanfang , Hoog Jeremy , Erdmann-Gilmore Petra , Primeau Tina , Huang Shixia , Edwards Dean P. , Wang Xiaowei , Wang Xuya , Kawaler Emily , Mani D.R. , Clauser Karl R. , Gao Feng , Luo Jingqin , Davies Sherri R. , Johnson Gary L. , Huang Kuan-lin , Yoon Christopher J. , Ding Li , Fenyö David , Ellis Matthew J. , Townsend R. Reid , Held Jason M. , Carr Steven A. , Ma Cynthia X.
Published: March 2023

Response markers
Supplementary Table S1 from ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Authors: Shukla Vivek , Rao Mahadev , Zhang Hongen , Beers Jeanette , Wangsa Darawalee , Wangsa Danny , Buishand Floryne O. , Wang Yonghong , Yu Zhiya , Stevenson Holly S. , Reardon Emily S. , McLoughlin Kaitlin C. , Kaufman Andrew S. , Payabyab Eden C. , Hong Julie A. , Zhang Mary , Davis Sean , Edelman Daniel , Chen Guokai , Miettinen Markku M. , Restifo Nicholas P. , Ried Thomas , Meltzer Paul A. , Schrump David S.
Published: March 2023

Antibodies and Primers
Supplemental Table S6-9 from Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma
Authors: Lin De-Chen , Mayakonda Anand , Dinh Huy Q. , Huang Pinbo , Lin Lehang , Liu Xiaoping , Ding Ling-wen , Wang Jie , Berman Benjamin P. , Song Er-Wei , Yin Dong , Koeffler H. Phillip
Published: March 2023

Files containing results related to methylation ITH
Supplementary Figure S3 from ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Authors: Shukla Vivek , Rao Mahadev , Zhang Hongen , Beers Jeanette , Wangsa Darawalee , Wangsa Danny , Buishand Floryne O. , Wang Yonghong , Yu Zhiya , Stevenson Holly S. , Reardon Emily S. , McLoughlin Kaitlin C. , Kaufman Andrew S. , Payabyab Eden C. , Hong Julie A. , Zhang Mary , Davis Sean , Edelman Daniel , Chen Guokai , Miettinen Markku M. , Restifo Nicholas P. , Ried Thomas , Meltzer Paul A. , Schrump David S.
Published: March 2023

HLA typing and Spectral Karyotyping (SKY) analysis
Supplementary Figure S2 from ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Authors: Shukla Vivek , Rao Mahadev , Zhang Hongen , Beers Jeanette , Wangsa Darawalee , Wangsa Danny , Buishand Floryne O. , Wang Yonghong , Yu Zhiya , Stevenson Holly S. , Reardon Emily S. , McLoughlin Kaitlin C. , Kaufman Andrew S. , Payabyab Eden C. , Hong Julie A. , Zhang Mary , Davis Sean , Edelman Daniel , Chen Guokai , Miettinen Markku M. , Restifo Nicholas P. , Ried Thomas , Meltzer Paul A. , Schrump David S.
Published: March 2023

qRT-PCR analysis of differentiation-related genes
Figure S3 from PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development
Authors: Sents Ward , Meeusen Bob , Kalev Petar , Radaelli Enrico , Sagaert Xavier , Miermans Eline , Haesen Dorien , Lambrecht Caroline , Dewerchin Mieke , Carmeliet Peter , Westermarck Jukka , Sablina Anna , Janssens Veerle
Published: March 2023

Histopathology pictures of neoplastic abnormalities in Ppp2r4 gene-trapped mice.
Figure S2 from PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development
Authors: Sents Ward , Meeusen Bob , Kalev Petar , Radaelli Enrico , Sagaert Xavier , Miermans Eline , Haesen Dorien , Lambrecht Caroline , Dewerchin Mieke , Carmeliet Peter , Westermarck Jukka , Sablina Anna , Janssens Veerle
Published: March 2023

Phosphatase assays in immunoprecipitates of several endogenous PP2A B-type subunits: time courses.
Supplementary Fig. 6 from Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models
Authors: Kossatz Susanne , Carney Brandon , Schweitzer Melanie , Carlucci Giuseppe , Miloushev Vesselin Z. , Maachani Uday B. , Rajappa Prajwal , Keshari Kayvan R. , Pisapia David , Weber Wolfgang A. , Souweidane Mark M. , Reiner Thomas
Published: March 2023

Biodistribution of [18F]PARPi in healthy ntv-a;p53fl/fl mice 2 h p.i.. Animals were injected with [18F]PARPi 2 hours prior to the biodistribution study (n=4). To control for uptake specificity, one group (n=4) was injected with 1 mg Olaparib 30min prior to the [18F]PARPi injection. The biodistribution shows specific (=blockable) uptake of [18F]PARPi in several organs (e.g. lymph nodes, spleen, pancreas, bone, indicating the presence of PARP1 expressing cells, whereas the uptake in liver and kidney cannot be blocked and is therefore due to excretion processes. N=4 per group, 1 mg Olaparib 30 min prior for blocking. Bl-blood, Br-brain, SG-salivary gland, LN-lymph node, He-heart, Sp-spleen, Pa-pancreas, Li-liver, Ki-kidney, St-stomach, SI-small intestine, LI-large intestine, Mu-muscle, Bo-bone.
Supplementary Fig. 1 from Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models
Authors: Kossatz Susanne , Carney Brandon , Schweitzer Melanie , Carlucci Giuseppe , Miloushev Vesselin Z. , Maachani Uday B. , Rajappa Prajwal , Keshari Kayvan R. , Pisapia David , Weber Wolfgang A. , Souweidane Mark M. , Reiner Thomas
Published: March 2023

PARP1 IHC staining. (a) PARP1 staining of frontal cortex autopsy tissue of a diffuse midline glioma patient. Only a subset of cells show PARP1 staining, while others are negative. Neurons show staining of the nucleoli, while cells of oligodendritic/astrocyte nature show PARP1 expression in the entire nucleus. Other cells, inclusing endothelial cells, show no PARP1 expression. The corresponding H&E is from the same area as the PARP1 stained image. (b) Physiological, non-tumor related PARP1 expression was observed in the brain of ntv-a;p53fl/fl mice in the Purkinje cell layer in the cerebellum and the dentate gyrus. Other brain areas showed low levels of PARP1 expression. (c) Example of PARP1 and H&E staining of tumor bearing ntv-a;p53fl/fl mice injected with DF1 cells at 4-6 weeks of age.
Supplementary materials and methods from Sunitinib Treatment Enhances Metastasis of Innately Drug-Resistant Breast Tumors
Authors: Wragg Joseph W. , Heath Victoria L. , Bicknell Roy
Published: March 2023

For supplementary figure 1
Supplemental Figures 1 to 6 from Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism
Authors: Braig Friederike , Kriegs Malte , Voigtlaender Minna , Habel Beate , Grob Tobias , Biskup Karina , Blanchard Veronique , Sack Markus , Thalhammer Anja , Ben Batalla Isabel , Braren Ingke , Laban Simon , Danielczyk Antje , Goletz Steffen , Jakubowicz Elzbieta , Märkl Bruno , Trepel Martin , Knecht Rainald , Riecken Kristoffer , Fehse Boris , Loges Sonja , Bokemeyer Carsten , Binder Mascha
Published: March 2023

Supplemental Figures 1 to 6 from Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism
Supplementary figure 1 from Sunitinib Treatment Enhances Metastasis of Innately Drug-Resistant Breast Tumors
Authors: Wragg Joseph W. , Heath Victoria L. , Bicknell Roy
Published: March 2023

Sunitinib resistance inheritance. Tumour cells were isolated from 4T1 tumours displaying acquired (responsive cohort) or innate (non-responsive cohort) resistance to sunitinib treatment in vivo and cultured for 2 weeks. A, tumour growth curves of the selected tumours from each cohort. 2.5 x 105 tumour cells from each culture along with treatment naïve 4T1 tumour cells were innoculated into Balb/c mice and the tumours allowed to grow to 600 mm3 with or without 40 mg/Kg sunitinib treatment. B, tumour growth curves (mean {plus minus} SEM) and Kaplan-meier plots for each inoculation, split into Untreated (green), Responsive (blue) and Non-responsive (red) cohorts. N-numbers as shown.
Supplemental Table S1 from Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future
Authors: Valent Peter , Akin Cem , Hartmann Karin , Nilsson Gunnar , Reiter Andreas , Hermine Olivier , Sotlar Karl , Sperr Wolfgang R. , Escribano Luis , George Tracy I. , Kluin-Nelemans Hanneke C. , Ustun Celalettin , Triggiani Massimo , Brockow Knut , Gotlib Jason , Orfao Alberto , Schwartz Lawrence B. , Broesby-Olsen Sigurd , Bindslev-Jensen Carsten , Kovanen Petri T. , Galli Stephen J. , Austen K. Frank , Arber Daniel A. , Horny Hans-Peter , Arock Michel , Metcalfe Dean D.
Published: March 2023

Supplemental Table S1
Figure S6 from A Synthetic CD8α:MyD88 Coreceptor Enhances CD8+ T-cell Responses to Weakly Immunogenic and Lowly Expressed Tumor Antigens
Authors: Kaczanowska Sabina , Joseph Ann Mary , Guo Jitao , Tsai Alexander K , Lasola Jackline Joy , Younger Kenisha , Zhang Yuji , Gonzales Cruz Velasco , Davila Eduardo
Published: March 2023

These data demonstrate that neither checkpoint blockade using anti-PD-L1 or costimulation using anti-4-1BB antibodies enhance pmel CD8a:MyD88 T cells antitumor activity
Table S1 from R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis
Authors: Zhou Xiaolin , Geng Liying , Wang Degeng , Yi Haowei , Talmon Geoffrey , Wang Jing
Published: March 2023

shRNA targeting sequences and RT-PCR primer sequences
Figure S2 from A Synthetic CD8α:MyD88 Coreceptor Enhances CD8+ T-cell Responses to Weakly Immunogenic and Lowly Expressed Tumor Antigens
Authors: Kaczanowska Sabina , Joseph Ann Mary , Guo Jitao , Tsai Alexander K , Lasola Jackline Joy , Younger Kenisha , Zhang Yuji , Gonzales Cruz Velasco , Davila Eduardo
Published: March 2023

These data demonstrate that CD8a:MyD88 expression increases IFN gamma production and induces the expression of various co-stimulatory and co-inhibitory molecules on T cells.
SF1 from Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver–Dependent Manner
Authors: Brinker Amanda E. , Vivian Carolyn J. , Koestler Devin C. , Tsue Trevor T. , Jensen Roy A. , Welch Danny R.
Published: March 2023

Supplementary Figure S1: Genotyping of MNX strains. Representative gels showing genotyping of MNX and matching wild-type strains. Total DNA was isolated from tail clips of weanling mice. DNA was amplified using primers that span A: 9461 Câ†'T polymorphism in C57BL/6J mitochondria which does not allow the incorporation of a Bcl1 restriction site, which is present in FVB/NJ or B: 9348 Aâ†'G polymorphism present in BALB/cJ but not FVB/NJ which does not allow the restriction site for Pflf1 to incorporate, this DNA was then exposed to restriction enzymes, A: Bcl1 and B: Pflf1 and resolved on an agarose gel.
Supplementary Dataset 4 from Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis
Authors: Rokavec Matjaz , Horst David , Hermeking Heiko
Published: March 2023

Expression and H3K79me3 changes
Supplementary Dataset 3 from Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis
Authors: Rokavec Matjaz , Horst David , Hermeking Heiko
Published: March 2023

Expression and H3K4me3 changes
Supplementary Table and Figure Legends from T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors
Authors: Manzo Teresa , Sturmheit Tabea , Basso Veronica , Petrozziello Elisabetta , Hess Michelini Rodrigo , Riba Michela , Freschi Massimo , Elia Angela R. , Grioni Matteo , Curnis Flavio , Protti Maria Pia , Schumacher Ton N. , Debets Reno , Swartz Melody A. , Corti Angelo , Bellone Matteo , Mondino Anna
Published: March 2023

Legends for Supplementary Table S1 and Supplementary Figures S1-S8.
Supplementary Table S1 from T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors
Authors: Manzo Teresa , Sturmheit Tabea , Basso Veronica , Petrozziello Elisabetta , Hess Michelini Rodrigo , Riba Michela , Freschi Massimo , Elia Angela R. , Grioni Matteo , Curnis Flavio , Protti Maria Pia , Schumacher Ton N. , Debets Reno , Swartz Melody A. , Corti Angelo , Bellone Matteo , Mondino Anna
Published: March 2023

LIMMA modeling of expression data.
Supplementary Methods and References. from T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors
Authors: Manzo Teresa , Sturmheit Tabea , Basso Veronica , Petrozziello Elisabetta , Hess Michelini Rodrigo , Riba Michela , Freschi Massimo , Elia Angela R. , Grioni Matteo , Curnis Flavio , Protti Maria Pia , Schumacher Ton N. , Debets Reno , Swartz Melody A. , Corti Angelo , Bellone Matteo , Mondino Anna
Published: March 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Figure S4 from Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors
Authors: Gauthier Ludiane , Corgnac Stéphanie , Boutet Marie , Gros Gwendoline , Validire Pierre , Bismuth Georges , Mami-Chouaib Fathia
Published: March 2023

The alphaE cytoplasmic tail is required for Pxn-dependent CD103 polarization and CD103-mediated early T-cell signaling
Figure S2 from Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors
Authors: Gauthier Ludiane , Corgnac Stéphanie , Boutet Marie , Gros Gwendoline , Validire Pierre , Bismuth Georges , Mami-Chouaib Fathia
Published: March 2023

T-cell treatment with saracatinib or infection with shRNA targeting Pxn does not alter cell viability and cell surface protein expression levels
Supplementary Figure 3 from Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression
Authors: Tsukamoto Hirotake , Fujieda Koji , Hirayama Masatoshi , Ikeda Tokunori , Yuno Akira , Matsumura Keiko , Fukuma Daiki , Araki Kimi , Mizuta Hiroshi , Nakayama Hideki , Senju Satoru , Nishimura Yasuharu
Published: March 2023

Myeloid cell-derived sIL-6R in tumor-bearing mice modulates CD4+ T-cell property.
Figure S1 from Mesenchymal Stem Cells Promote Hepatocarcinogenesis via lncRNA–MUF Interaction with ANXA2 and miR-34a
Authors: Yan Xinlong , Zhang Dongdong , Wu Wei , Wu Shuheng , Qian Jingfeng , Hao Yajing , Yan Fang , Zhu Pingping , Wu Jiayi , Huang Guanling , Huang Yinghui , Luo Jianjun , Liu Xinhui , Liu Benyu , Chen Xiaomin , Du Ying , Chen Runsheng , Fan Zusen
Published: March 2023

HCC-MSCs significantly induced the EMT pathway of HCC cells.
Supplementary Table S1-S4 from PACE4 Undergoes an Oncogenic Alternative Splicing Switch in Cancer
Authors: Couture Frédéric , Sabbagh Robert , Kwiatkowska Anna , Desjardins Roxane , Guay Simon-Pierre , Bouchard Luigi , Day Robert
Published: March 2023

Primer sequences and antibodies specifications
Supplementary figure 9-10 from Prominent Oncogenic Roles of EVI1 in Breast Carcinoma
Authors: Wang Hui , Schaefer Thorsten , Konantz Martina , Braun Martin , Varga Zsuzsanna , Paczulla Anna M. , Reich Selina , Jacob Francis , Perner Sven , Moch Holger , Fehm Tanja N. , Kanz Lothar , Schulze-Osthoff Klaus , Lengerke Claudia
Published: March 2023

Validation of KISS1 mRNA overexpression in BC cells transduced with KISS1 overexpression lentiviruses and verification of the effects of KISS1 induction or RKI-1447/Kp-10 supplementation, on migration/growth of Hs 578T or MDA-MB-231 control cells.
Supplementary Methods from FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity
Authors: Gaymes Terry J. , Mohamedali Azim , Eiliazadeh Anthony L. , Darling David , Mufti Ghulam J.
Published: March 2023

Additional methodology including preparation of DNA repair substrates, Cell culture, RT-PCR, GFP assays, cell cycle analysis, western blotting, immunofluorescence, sister chromatid exchange and mutation analysis
Supplementary Figure and Table Legends from Prominent Oncogenic Roles of EVI1 in Breast Carcinoma
Authors: Wang Hui , Schaefer Thorsten , Konantz Martina , Braun Martin , Varga Zsuzsanna , Paczulla Anna M. , Reich Selina , Jacob Francis , Perner Sven , Moch Holger , Fehm Tanja N. , Kanz Lothar , Schulze-Osthoff Klaus , Lengerke Claudia
Published: March 2023

Supplementary Figure and Table Legends
Supplemenetary Figure Legends from ESE3 Inhibits Pancreatic Cancer Metastasis by Upregulating E-Cadherin
Authors: Zhao Tiansuo , Jiang Wenna , Wang Xiuchao , Wang Hongwei , Zheng Chen , Li Yang , Sun Yan , Huang Chongbiao , Han Zhi-bo , Yang Shengyu , Jia Zhiliang , Xie Keping , Ren He , Hao Jihui
Published: March 2023

Figure S1. Effects of Methylation-reducing agent and ESE3 on pancreatic cancer growth and migration in vitro. Figure S2. The basal expression of ESE3 in four PDAC cell lines by Western blotting experiment. Figure S3. Regulation of EMT marker expression by ESE3. Figure S4. Impact of altered expression of ESE3 on pancreatic tumor growth in nude mice.
Figure S1 from Zeb1 in Stromal Myofibroblasts Promotes Kras-Driven Development of Pancreatic Cancer
Authors: Sangrador Irene , Molero Xavier , Campbell Fiona , Franch-Expósito Sebastià , Rovira-Rigau Maria , Samper Esther , Domínguez-Fraile Manuel , Fillat Cristina , Castells Antoni , Vaquero Eva C.
Published: March 2023

Zeb1 hemizygosity doesn't prevent long term development of PDAC in 30-weeks old KPC;Z+/-
Supplementary Material and Methods from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Authors: Wang Hangxiang , Lu Zhongjie , Wang Lijiang , Guo Tingting , Wu Jiaping , Wan Jianqin , Zhou Liqian , Li Hui , Li Zhen , Jiang Donghai , Song Penghong , Xie Haiyang , Zhou Lin , Xu Xiao , Zheng Shusen
Published: March 2023

Description of synthesis of compounds, additional experiments and procedures, and Table S1
CTLA4 blockade induces T cell activation from CTLA4 Promotes Tyk2-STAT3–Dependent B-cell Oncogenicity
Authors: Herrmann Andreas , Lahtz Christoph , Nagao Toshikage , Song Joo Y. , Chan Wing C. , Lee Heehyoung , Yue Chanyu , Look Thomas , Mülfarth Ronja , Li Wenzhao , Jenkins Kurt , Williams John , Budde Lihua E. , Forman Stephen , Kwak Larry , Blankenstein Thomas , Yu Hua
Published: March 2023

Suppl. Fig. S2 showing improved Th1 and Th2 maturation and increased CD3 T cell activation upon CTLA4 blockade in vivo.
Supplementary Movie 2 from Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction
Authors: Allen Julie K. , Armaiz-Pena Guillermo N. , Nagaraja Archana S. , Sadaoui Nouara C. , Ortiz Tatiana , Dood Robert , Ozcan Merve , Herder Danielle M. , Haemmerle Monika , Gharpure Kshipra M. , Rupaimoole Rajesha , Previs Rebecca A. , Wu Sherry Y. , Pradeep Sunila , Xu Xiaoyun , Han Hee Dong , Zand Behrouz , Dalton Heather J. , Taylor Morgan , Hu Wei , Bottsford-Miller Justin , Moreno-Smith Myrthala , Kang Yu , Mangala Lingegowda S. , Rodriguez-Aguayo Cristian , Sehgal Vasudha , Spaeth Erika L. , Ram Prahlad T. , Wong Stephen T.C. , Marini Frank C. , Lopez-Berestein Gabriel , Cole Steve W. , Lutgendorf Susan K. , De Biasi Mariella , Sood Anil K.
Published: March 2023

CARS imaging of ex vivo ovarian cancer samples
Figure S8 to S10 from Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression
Authors: Kim Sungjin , Alsaidan Omar Awad , Goodwin Octavia , Li Qianjin , Sulejmani Essilvo , Han Zhen , Bai Aiping , Albers Thomas , Beharry Zanna , Zheng Y. George , Norris James S. , Szulc Zdzislaw M. , Bielawska Alicja , Lebedyeva Iryna , Pegan Scott D. , Cai Houjian
Published: March 2023

Figure S8. Identifying compounds inhibiting Src myristoylation by Click chemistry. Figure S9. Structures and/or IC50 values of LCL and GRU compounds. Figure S10. Loss of myristoylation inhibits the localization of Src kinase at the cytoplasmic membrane.
Figure S6 from Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates
Authors: Caculitan Niña G. , dela Cruz Chuh Josefa , Ma Yong , Zhang Donglu , Kozak Katherine R. , Liu Yichin , Pillow Thomas H. , Sadowsky Jack , Cheung Tommy K. , Phung Qui , Haley Benjamin , Lee Byoung-Chul , Akita Robert W. , Sliwkowski Mark X. , Polson Andrew G.
Published: March 2023

Supplementary Figure 6: Predicted catabolic pathway for mAb-VC-MMAE ADCs.
Figure S1 to S4 from Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression
Authors: Kim Sungjin , Alsaidan Omar Awad , Goodwin Octavia , Li Qianjin , Sulejmani Essilvo , Han Zhen , Bai Aiping , Albers Thomas , Beharry Zanna , Zheng Y. George , Norris James S. , Szulc Zdzislaw M. , Bielawska Alicja , Lebedyeva Iryna , Pegan Scott D. , Cai Houjian
Published: March 2023

Figure S1. Knockdown of NMT1 by shRNA-NMT1 inhibits Src myristoylation and proliferation of prostate cancer cells. Figure S2. Knockdown of Src and Fyn kinase inhibits the growth of prostate cancer cells. Figure S3. The contribution of myristoylation and palmitoylation to the activity of SFKs. Figure S4. Fyn kinase has no synergistic effect with androgen receptor (AR).
Supplementary Table 3 from ERα Binding by Transcription Factors NFIB and YBX1 Enables FGFR2 Signaling to Modulate Estrogen Responsiveness in Breast Cancer
Authors: Campbell Thomas M. , Castro Mauro A. A. , de Oliveira Kelin Gonçalves , Ponder Bruce A. J. , Meyer Kerstin B.
Published: March 2023

Full data set obtained in RIME experiment.
Supplementary Tables S1 through S5 and Supplementary Figures S1 and S2 from Therapeutic Potential of Bacteria against Solid Tumors
Authors: Hatzikirou Haralampos , López Alfonso Juan Carlos , Leschner Sara , Weiss Siegfried , Meyer-Hermann Michael
Published: March 2023

- (Table S1) Control parameter values considered in the tumor-effector cell recruitment model - (Table S2) Parameter values estimated from the set of experiments corresponding to infection loads of 10^3 bacteria. - (Table S3) Parameter values estimated from the set of experiments corresponding to infection loads of5Ã-10^6 bacteria. - (Table S4) Parameter values estimated from the set of experiments corresponding to TNF-alpha administration. - (Table S5) Parameter values estimated from the set of experiments corresponding to infection loads of 10^3 bacteria and TNF-alpha administration. - (Figure S1) Long-term tumor control dependency on the initial number of effector cells E_0. - (Figure S2) Long-term tumor control dependency on the immune recruitment rate r.
Supplementary Methods from Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph+ Acute Lymphoblastic Leukemia
Authors: De Dominici Marco , Porazzi Patrizia , Soliera Angela Rachele , Mariani Samanta A. , Addya Sankar , Fortina Paolo , Peterson Luke F. , Spinelli Orietta , Rambaldi Alessandro , Martinelli Giovanni , Ferrari Anna , Iacobucci Ilaria , Calabretta Bruno
Published: March 2023

List of primers and antibodies used.
Supplementary Data from Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide
Authors: Kikuchi Jiro , Kuroda Yoshiaki , Koyama Daisuke , Osada Naoki , Izumi Tohru , Yasui Hiroshi , Kawase Takakazu , Ichinohe Tatsuo , Furukawa Yusuke
Published: March 2023

Supplementary Materials and Methods, Tables S1-5, and Figures S1-9
Supplementary Table S5 from Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle–Related Transcription and Attenuated Androgen Response
Authors: Horning Aaron M. , Wang Yao , Lin Che-Kuang , Louie Anna D. , Jadhav Rohit R. , Hung Chia-Nung , Wang Chiou-Miin , Lin Chun-Lin , Kirma Nameer B. , Liss Michael A. , Kumar Addanki P. , Sun LuZhe , Liu Zhijie , Chao Wei-Ting , Wang Qianben , Jin Victor X. , Chen Chun-Liang , Huang Tim H.-M.
Published: March 2023

Supplementary Table S5: Predictive values of the subcluser E gene panel for biochemical recurrence
Supplementary information from Transition of Mesenchymal and Epithelial Cancer Cells Depends on α1-4 Galactosyltransferase-Mediated Glycosphingolipids
Authors: Jacob Francis , Alam Shahidul , Konantz Martina , Liang Ching-Yeu , Kohler Reto S. , Everest-Dass Arun V. , Huang Yen-Lin , Rimmer Natalie , Fedier Andre , Schötzau Andreas , Lopez Monica Nunez , Packer Nicolle H. , Lengerke Claudia , Heinzelmann-Schwarz Viola
Published: March 2023

This file contains: Supplementary material & methods Supplementary Figure S1 Globoside GSL synthesizing glycosyltransferases show elevated gene expression in epithelial tissue samples. Supplementary Figure S2 EMT marker gene expression in 47 ovarian cancer cell lines. Supplementary Figure S3 Single cell sorting strategy after transient transfection of sgRNA CRISPR-Cas9 constructs. Supplementary Figure S4 Quantification of glycans released from glycosphingolipids in wildtype and Î"A4GALT ovarian cancer cells using LC-ESI-MS/MS. Supplementary Figure S5 Dissemination of Î"A4GALT compared to IGROV1 wildtype cells. Supplementary Figure S6 The aspartate-any residue-aspartate motif is required for enzymatic activity of A4GALT. Supplementary Figure S7 Bicistronic expression of E-cadherinEGFP and A4GALT DXA shows enhanced extravasation in vivo. Supplementary Figure S8 Genetic depletion of A4GALT correlates with the absence of globosides in ovarian cancer cells representing the four different states of EMT. Supplementary Figure S9 Fluorescently labelled cells were transplanted into the Duct of Cuvier of 48 hpf zebrafish embryos and cells followed for 2-3 days. Supplementary Figure S10 Increased E-cadherin in SKOV3ip coincides with SLUG expression and histone modifications. Supplementary Table S1 Quantification of glycans released from glycosphingolipids in wildtype and Î"A4GALT ovarian cancer cells using LC-ESI-MS/MS. Supplementary Table S2 Cell lines used in this study. Supplementary Table S3 Table providing details of oligonucleotides used in this study. Supplementary references required for supplementary information
Supplementary Table S1 from Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle–Related Transcription and Attenuated Androgen Response
Authors: Horning Aaron M. , Wang Yao , Lin Che-Kuang , Louie Anna D. , Jadhav Rohit R. , Hung Chia-Nung , Wang Chiou-Miin , Lin Chun-Lin , Kirma Nameer B. , Liss Michael A. , Kumar Addanki P. , Sun LuZhe , Liu Zhijie , Chao Wei-Ting , Wang Qianben , Jin Victor X. , Chen Chun-Liang , Huang Tim H.-M.
Published: March 2023

Supplementary Table S1: qPCR Primers for androgen responsive genes
Supplementary text from ConsensusDriver Improves upon Individual Algorithms for Predicting Driver Alterations in Different Cancer Types and Individual Patients
Authors: Bertrand Denis , Drissler Sibyl , Chia Burton K. , Koh Jia Yu , Li Chenhao , Suphavilai Chayaporn , Tan Iain Beehuat , Nagarajan Niranjan
Published: March 2023

Supplementary text that describes parameters used for driver prediction methods and analysis of machine learning approaches for consensus generation.
supplementary material and methods from Visualization of Breast Cancer Metabolism Using Multimodal Nonlinear Optical Microscopy of Cellular Lipids and Redox State
Authors: Hou Jue , Williams Joshua , Botvinick Elliot L. , Potma Eric O. , Tromberg Bruce J.
Published: March 2023

details description of the system set up and other experiments
Table S3 from Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII–p38MAPK–pS249/T252RB Pathway
Authors: Yu-Lee Li-Yuan , Yu Guoyu , Lee Yu-Chen , Lin Song-Chang , Pan Jing , Pan Tianhong , Yu Kai-Jie , Liu Bin , Creighton Chad J. , Rodriguez-Canales Jaime , Villalobos Pamela A. , Wistuba Ignacio I. , de Nadal Eulalia , Posas Francesc , Gallick Gary E. , Lin Sue-Hwa
Published: March 2023

Selected factors secreted from Day 30 differentiated osteoblasts.
figure S2 from Visualization of Breast Cancer Metabolism Using Multimodal Nonlinear Optical Microscopy of Cellular Lipids and Redox State
Authors: Hou Jue , Williams Joshua , Botvinick Elliot L. , Potma Eric O. , Tromberg Bruce J.
Published: March 2023

Figure S2 contains extra experiments to prove that deuterium labeling can work in tracking lipid biosynthesis.
Supplemental Table 1 from Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer
Authors: Carey Jason. P.W. , Karakas Cansu , Bui Tuyen , Chen Xian , Vijayaraghavan Smruthi , Zhao Yang , Wang Jing , Mikule Keith , Litton Jennifer K. , Hunt Kelly K. , Keyomarsi Khandan
Published: March 2023

Clinical and pathological characteristics of 53 triple negative breast carcinoma patients
Supplementary Tables S1-S3 from The Inhibitory NKR-P1B:Clr-b Recognition Axis Facilitates Detection of Oncogenic Transformation and Cancer Immunosurveillance
Authors: Tanaka Miho , Fine Jason H. , Kirkham Christina L. , Aguilar Oscar A. , Belcheva Antoaneta , Martin Alberto , Ketela Troy , Moffat Jason , Allan David S.J. , Carlyle James R.
Published: March 2023

Supplementary Tables S1 to S3 with captions. Table S1 shows PCR primers; Table S2 shows mutant vectors; Table S3 shows lymphoma phenotypes.
Supplemental Figures 1-7 and Legends from Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies
Authors: Rizzolio Sabrina , Battistini Chiara , Cagnoni Gabriella , Apicella Maria , Vella Viviana , Giordano Silvia , Tamagnone Luca
Published: March 2023

Suppl. Figures 1 and 2 show supporting evidence concerning the role of Nrp2 in non oncogene-addicted carcinoma cells A549 and PC3, and EGFR-addicted cancer cells PC9. Suppl. Fig. 3 shows supporting information concerning the role of Nrp2 and its splice isoforms in Met-addicted cells. Suppl. Fig. 4 contains supporting evidence about concomitant Nrp2 and EGFR regulation in addicted cells which developed resistance to targeted therapy. Suppl. Fig. 5 contains supporting evidence about EGFR endocytosis and protein stability in targeted-therapy-resistant cells, as well as KIAA1199 knock-down validation data in the same cells. Suppl. Fig. 6 shows supporting evidence about IKB regulation by Nrp2, as well as validation data on KIAA1199 gene silencing in different cancer cells. Suppl. Fig. 7 describes the impact of Nrp2-silencing in multiple melanoma cells, as well as in mesenchymal-type MDAMB231 carcinoma cells.
Figure S4 from A Pyrrole-Imidazole Polyamide Is Active against Enzalutamide-Resistant Prostate Cancer
Authors: Kurmis Alexis A. , Yang Fei , Welch Timothy R. , Nickols Nicholas G. , Dervan Peter B.
Published: March 2023

Plasma bioavailability of ARE-1
supplementary information-R from PDSS2 Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism
Authors: Li Yan , Lin Shuhai , Li Lei , Tang Zhi , Hu Yumin , Ban Xiaojiao , Zeng Tingting , Zhou Ying , Zhu Yinghui , Gao Song , Deng Wen , Zhang Xiaoshi , Xie Dan , Yuan Yunfei , Huang Peng , Li Jinjun , Cai Zongwei , Guan Xin-Yuan
Published: March 2023

supplementary information (word)
Figure S5 from Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors
Authors: Ménard Ludovic , Floc'h Nicolas , Martin Matthew J. , Cross Darren A.E.
Published: March 2023

Isogenic cell lines show sensitivity profiles to the different generation TKIs. Mutant-EGFR is unphosphorylated in osimertinib resistant cell lines.
Supplementary Figure Legends and Materials from AMPK–Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation
Authors: Saha Manipa , Kumar Saurav , Bukhari Shoiab , Balaji Sai A. , Kumar Prashant , Hindupur Sravanth K. , Rangarajan Annapoorni
Published: March 2023

File contains figure legends for supplementary figure and method and material
Supplemental Methods from Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R–YAP Axis
Authors: Zhu Hong , Wang Dan-Dan , Yuan Tao , Yan Fang-Jie , Zeng Chen-Ming , Dai Xiao-Yang , Chen Zi-bo , Chen Ying , Zhou Tianyi , Fan Guang-Han , Ying Meidan , Cao Ji , Luo Peihua , Liu Xi-Jie , Hu Yuandong , Peng Yong , He Qiaojun , Yang Bo
Published: March 2023

Materials and Methods for Supplemental Figures
Supplementary Methods from miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer
Authors: Yan Ting-Ting , Ren Lin-Lin , Shen Chao-Qin , Wang Zhen-Hua , Yu Ya-Nan , Liang Qian , Tang Jia-Yin , Chen Ying-Xuan , Sun Dan-Feng , Zgodzinski Witold , Majewski Marek , Radwan Piotr , Kryczek Ilona , Zhong Ming , Chen Jinxian , Liu Qiang , Zou Weiping , Chen Hao-Yan , Hong Jie , Fang Jing-Yuan
Published: March 2023

This file contains methods which were not included in the main text.
Supplementary Figure Legends from miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer
Authors: Yan Ting-Ting , Ren Lin-Lin , Shen Chao-Qin , Wang Zhen-Hua , Yu Ya-Nan , Liang Qian , Tang Jia-Yin , Chen Ying-Xuan , Sun Dan-Feng , Zgodzinski Witold , Majewski Marek , Radwan Piotr , Kryczek Ilona , Zhong Ming , Chen Jinxian , Liu Qiang , Zou Weiping , Chen Hao-Yan , Hong Jie , Fang Jing-Yuan
Published: March 2023

This file contains figure legends corresponding to supplementary figures.
Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7, Figure S8, Table S1, Supplementary Materials and Methods from S-Nitrosylation of cIAP1 Switches Cancer Cell Fate from TNFα/TNFR1-Mediated Cell Survival to Cell Death
Authors: Romagny Sabrina , Bouaouiche Sarra , Lucchi Géraldine , Ducoroy Patrick , Bertoldo Jean B. , Terenzi Hernan , Bettaieb Ali , Plenchette Stéphanie
Published: March 2023

This file contains: Figure S1: Apoptosis determined by annexin V-FITC/7-AAD. Figure S2: NO prevents TNFa-induced classical NF-kB signaling pathway. Figure S3: Detection of S-nitrosylation of cIAP1 with the biotin-switch assay. Figure S4: Example of MALDI-TOF-MS spectra of S-nitrosylated cIAP1. Figure S5: SW480 stable cell line expressing 6myc-cIAP1-C571/574H. Figure S6: Characterization of apoptosis induced by GTN/TNFa. Figure S7: Functional analysis of the ubiquitin E3 ligase activity of cIAP1 mutants. Figure S8: NO prevents TNFa-mediated complex I to promote complex II. Table S1: TNFa concentration in media from human macrophages treated with 5-Fluorouracil/oxaliplatin. Supplementary Materials and Methods.
Suppl Table S1 from PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth
Authors: Martín-Martín Natalia , Zabala-Letona Amaia , Fernández-Ruiz Sonia , Arreal Leire , Camacho Laura , Castillo-Martin Mireia , Cortazar Ana R. , Torrano Verónica , Astobiza Ianire , Zúñiga-García Patricia , Ugalde-Olano Aitziber , Loizaga-Iriarte Ana , Unda Miguel , Valcárcel-Jiménez Lorea , Arruabarrena-Aristorena Amaia , Piva Marco , Sánchez-Mosquera Pilar , Aransay Ana M. , Gomez-Muñoz Antonio , Barrio Rosa , Sutherland James D. , Carracedo Arkaitz
Published: March 2023

Suppl Table S1
Supplementary text from Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2–ERα–GREB1 Transcriptional Axis
Authors: Wu Yanming , Zhang Zhao , Cenciarini Mauro E. , Proietti Cecilia J. , Amasino Matias , Hong Tao , Yang Mei , Liao Yiji , Chiang Huai-Chin , Kaklamani Virginia G. , Jeselsohn Rinath , Vadlamudi Ratna K. , Huang Tim Hui-Ming , Li Rong , De Angelis Carmine , Fu Xiaoyong , Elizalde Patricia V. , Schiff Rachel , Brown Myles , Xu Kexin
Published: March 2023

This file contains the supplementary information including materials and methods, primer sequences, clinicopathological characteristics of patient samples and supplemental figures legends.
Table S1 and S2 from Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs
Authors: Fang Fang , Cardenas Horacio , Huang Hao , Jiang Guanglong , Perkins Susan M. , Zhang Chi , Keer Harold N. , Liu Yunlong , Nephew Kenneth P. , Matei Daniela
Published: March 2023

Table S1. Genes demethylated by Guadecitabine Table S2. Differentially expressed genes
Supplemental Data from Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ
Authors: Wang Zhen , Liu Peng , Zhou Xin , Wang Tianxiang , Feng Xu , Sun Yi-Ping , Xiong Yue , Yuan Hai-Xin , Guan Kun-Liang
Published: March 2023

Figure S1. Stimulation of ETAR activates YAP/TAZ Figure S2. Effect of ET-1 on YAP/TAZ in prostate cancer cells and breast cancer cells Figure S3. ET-1 acts through ROCK, actin cytoskeleton to stimulate YAP/TAZ Figure S4. Expression levels of ETAR in tumors
Figure S1, S2, S3 from Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs
Authors: Fang Fang , Cardenas Horacio , Huang Hao , Jiang Guanglong , Perkins Susan M. , Zhang Chi , Keer Harold N. , Liu Yunlong , Nephew Kenneth P. , Matei Daniela
Published: March 2023

Figure S1. (A) Predicted cancer/stromal signatures in TCGA and our data. (B) Correlation between NMF and ESTIMATION estimated cancer cell purity in TCGA OV data. (C,D) Predicted relative proportion of cancer/stromal cell in our and TCGA data. Figure S2. Full list of pathways enriched by differentially expressed genes induced by guadecitabine. Figure S3. A-D. Spearman correlation between the beta values of 24 CpG sites within the promoters of 19 genes significantly demethylated in ascites samples and predicted proportions of B cells (A), T cells (B), NK cells (C), and total cells (D). E-H. Spearman correlation between the beta values of 352 CpG sites within the promoters of 94 genes significantly demethylated in tumor samples and predicted proportion of B cells (E), T cells (F), NK cells (G), and total cells (H). Complete sets of correlation coefficients are provided in Supplementary Table 8. X axis corresponds to Spearman correlation coefficients.
Supplementary File 4 from Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes
Authors: Abbas Hussein A. , Bui Ngoc Hoang Bao , Rajapakshe Kimal , Wong Justin , Gunaratne Preethi , Tsai Kenneth Y. , Coarfa Cristian , Flores Elsa R.
Published: March 2023

Components of tumor progression TAp63 (4.1) and Î"Np63 (4.2) signatures used in this study. Pathways enriched in TAp63 (4.3) and Î"Np63 (4.4) tumor progression signatures.
Tables S1-S4 and Figures S1-S4 from Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program
Authors: Luan Haitao , Mohapatra Bhopal , Bielecki Timothy A. , Mushtaq Insha , Mirza Sameer , Jennings Tameka A. , Clubb Robert J. , An Wei , Ahmed Dena , El-Ansari Rokaya , Storck Matthew D. , Mishra Nitish K. , Guda Chittibabu , Sheinin Yuri M. , Meza Jane L. , Raja Srikumar , Rakha Emad A. , Band Vimla , Band Hamid
Published: March 2023

Tables and Figures
Supplemental Table 7 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Authors: Scott Milcah C. , Temiz Nuri A. , Sarver Anne E. , LaRue Rebecca S. , Rathe Susan K. , Varshney Jyotika , Wolf Natalie K. , Moriarity Branden S. , O'Brien Timothy D. , Spector Logan G. , Largaespada David A. , Modiano Jaime F. , Subramanian Subbaya , Sarver Aaron L.
Published: March 2023

Supplemental Table 7. Immunohistochemistry validation of Immune 1 and Immune 2 GCESS
Supplementary data 1 from MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL
Authors: Zhou Mi , Zhou Kuangguo , Cheng Ling , Chen Xing , Wang Jue , Wang Xiao-Min , Zhang Yingchi , Yu Qilin , Zhang Shu , Wang Di , Huang Liang , Huang Mei , Ma Ding , Cheng Tao , Wang Cong-Yi , Yuan Weiping , Zhou Jianfeng
Published: March 2023

This file contains supplemental Materials and Methods, References, supplemental data of MBD2 deficiency phenotype in normal hematopoiesis and T-ALL, and the correlation between MBD2 and Wnt signaling in primary T-ALL samples.
Supplementary Figure 1 from Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism
Authors: Rashmi Ramachandran , Huang Xiaojing , Floberg John M. , Elhammali Adnan E. , McCormick Michael L. , Patti Gary J. , Spitz Douglas R. , Schwarz Julie K.
Published: March 2023

Effects of TR1 and TR2 knock down on 2-DG treated CaSki cells. (A & C) CaSki and SiHa cells were transfected with control and TR1, TR2 and TR1+TR2 siRNA and after 24h, treated with 20mM 2-DG, 48h and CFA was performed. *p<0.01 Control + DG vs TR1/TR2+DG, *p<0.01 Control vs TR1/2 siRNA. (B & D) CaSki and SiHa cells were transfected with scrambled and TR1 and TR2 siRNA and protein levels were determined by Western blot.
Supplemental File 1 from Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition
Authors: Ishizawa Jo , Nakamaru Kenji , Seki Takahiko , Tazaki Koichi , Kojima Kensuke , Chachad Dhruv , Zhao Ran , Heese Lauren , Ma Wencai , Ma Man Chun John , DiNardo Courtney , Pierce Sherry , Patel Keyur P. , Tse Archie , Davis R. Eric , Rao Arvind , Andreeff Michael
Published: March 2023

Detailed results in viability assay of Oncopanel cell lines treated with MDM2 inhibitors.
Supplementary Information from Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Authors: Niklasson Mia , Maddalo Gianluca , Sramkova Zuzana , Mutlu Ercan , Wee Shimei , Sekyrova Petra , Schmidt Linnéa , Fritz Nicolas , Dehnisch Ivar , Kyriatzis Gregorios , Krafcikova Michaela , Carson Brittany B. , Feenstra Jennifer M. , Marinescu Voichita D. , Segerman Anna , Haraldsson Martin , Gustavsson Anna-Lena , Hammarström Lars G.J. , Jenmalm Jensen Annika , Uhrbom Lene , Altelaar A.F. Maarten , Linnarsson Sten , Uhlén Per , Trantirek Lukas , Vincent C. Theresa , Nelander Sven , Enger Per Øyvind , Andäng Michael
Published: March 2023

Supplementary Figure Legends and Materials and Methods
Supplemental Figure Legends from Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells
Authors: Gendelman Rina , Xing Heming , Mirzoeva Olga K. , Sarde Preeti , Curtis Christina , Feiler Heidi S. , McDonagh Paul , Gray Joe W. , Khalil Iya , Korn W. Michael
Published: March 2023

Supplemental Figure Legends
Supplemental Dataset B - GDH1/2 effect on the metabolome. from Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities
Authors: Waitkus Matthew S. , Pirozzi Christopher J. , Moure Casey J. , Diplas Bill H. , Hansen Landon J. , Carpenter Austin B. , Yang Rui , Wang Zhaohui , Ingram Brian O. , Karoly Edward D. , Mohney Robert P. , Spasojevic Ivan , McLendon Roger E. , Friedman Henry S. , He Yiping , Bigner Darell D. , Yan Hai
Published: March 2023

Metabolomics analysis of GDH1/2 expression in gliomagenic neural progenitor cells.
Figure S1- S10 from Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities
Authors: Waitkus Matthew S. , Pirozzi Christopher J. , Moure Casey J. , Diplas Bill H. , Hansen Landon J. , Carpenter Austin B. , Yang Rui , Wang Zhaohui , Ingram Brian O. , Karoly Edward D. , Mohney Robert P. , Spasojevic Ivan , McLendon Roger E. , Friedman Henry S. , He Yiping , Bigner Darell D. , Yan Hai
Published: March 2023

Supplemental Figures 1 through 10.
Figure S2 from Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma
Authors: Reap Elizabeth A. , Suryadevara Carter M. , Batich Kristen A. , Sanchez-Perez Luis , Archer Gary E. , Schmittling Robert J. , Norberg Pamela K. , Herndon James E. , Healy Patrick , Congdon Kendra L. , Gedeon Patrick C. , Campbell Olivia C. , Swartz Adam M. , Riccione Katherine A. , Yi John S. , Hossain-Ibrahim Mohammed K. , Saraswathula Anirudh , Nair Smita K. , Dunn-Pirio Anastasie M. , Broome Taylor M. , Weinhold Kent J. , Desjardins Annick , Vlahovic Gordana , McLendon Roger E. , Friedman Allan H. , Friedman Henry S. , Bigner Darell D. , Fecci Peter E. , Mitchell Duane A. , Sampson John H.
Published: March 2023

Ex vivo analysis of CMV pp65-specific CD8+ T cells in circulation before and after immunotherapy.