bluuebunny/crossref_metadata_2025 huggingface dataset:
Complexité du processus d'internationalisation de la PME: vers un enrichissement de l'analyse behavioriste
Authors: AGERON Blandine , HUAULT Isabelle
Published: March 2024

The objective of this article is to describe the principle characteristics of the process of internalization of an SME. To expand on and enrich the dominant behaviorist model, it is pointed out that examining an enterprise's resources, and particularly its industrial capacity, is part of thinking internationally. The article goes beyond external analysis of the environment - suggested by behaviorist theory - to look at the complexity of the dynamics of being open to internationalization, focusing on elements that encompass marketing dimensions and, in particular, structural and industrial processes.
Quelles formes d'ambidextrie pour combiner innovations d'exploitation et d'exploration?
Authors: BRION Sébastien , FAVRE-BONTÉ Véronique , MOTHE Caroline
Published: March 2024

The present article studies the forms of ambidexterity used to combine exploration and exploitation innovations. Until now, the literature has identified archetypes based on structural and contextual ambidexterity. However, no research has yet identified how a multidivisional group can successfully combine 2 forms of innovation that are often considered incompatible. A qualitative study carried out within the SEB Group shows how SEB combines these 2 forms of ambidexterity in such a way as to reap the respective benefits of each form while partly alleviating their shortcomings. [PUB ABSTRACT]
¿Soluciones innovadoras o nuevos dogmas? cinco debates necesarios sobre la nueva gestión pública
Authors: ARELLANO GAULT David
Published: March 2024

The advocates of the so-called New Public Management (NPM) argue that a revolution is taking place which will radically alter public management as a discipline. Many of their ideas are currently being applied in several countries, among which are the United States, England and New Zealand. As well, for many multilateral organizations, such as the OECD and the World Bank - to name only two of the more enthusiastic - these ideas are the spearhead of reform within specific governments. In this article, the author examines these dilemmas which are the source of 5 important debates that need to take place: 1. accountability or innovation 2. participation or technical decision-making, 3. equity or market, 4. problem solving or programs management, and 5. leadership or "institutionality."
Esquisse d'une analyse des stratégies locales d'adaptation de l'ordre traditionnel face à la globalisation : une approche néo-institutionnaliste
Authors: BARABEL Michel , HUAULT Isabelle , LECA Bernard
Published: March 2024

Most recent works on the international diffusion of institutions have focused on the way in which practices spread globally and how to avoid confrontation with local institutions, by adapting these practices. In so doing, none of these works have considered the strategies local actors use to uphold the foundations of the traditional institutional order in the face of globalization pressures. This article explores this dimension, through an analysis of the strategies employed by actors in an industrial district to adapt to or resist the practices that tend to be spreading throughout the world. This study outlines an analytic framework of the strategies implemented by the actors to secure institutional resistance, a theme notoriously under-developed in institutional analysis. [PUBLICATION ABSTRACT]
Le rôle des facteurs institutionnels dans la décision d'externaliser
Authors: MARTIN Aude , BOURGEOIS Christophe
Published: March 2024

This study proves the part played by institutional factors in the decision to outsource. To do so, we use the principles developed by neo-institutional researchers. An empirical study was conducted with organizations working in the metallurgy field. The results we got clearly show that the insitutional environment influences managers in the decision to outsource an activity, and that this choice is determined by a mimetism phenomenon. While the outsourcing decision is characterized by an economic-centered logic, we cannot completely refute that it is also dependent on a non economic-centered logic. The search for legitimacy, another neo-institutional principle, is less clearly established.
La restructuration des services publics et les relations de travail dans l'administration publique québécoise
Authors: GRENIER Jean-Noël , MALO François Bernard
Published: March 2024

The coming to power of the liberal government in 2003 polarized Quebec's collective actors into 2 camps: promoters and opposers of the reforms proposed by the liberal government. This article takes stock of the labor relations situation in light of the reforms initiated by the government. The research shows that the liberal government initiatives are in line with a trajectory borrowed from English-speaking countries, but that the partial reforms of the processes and structures of collective negotiation are likely to restrain the flexibility of managers and unions. [PUB ABSTRACT]
Le management relationnel peut-il favoriser une gestion durable de l'entreprise ?
Authors: PERSAIS Eric
Published: March 2024

Corporate needs are expressed with more acuteness everyday within the business world. So as to secure their growth, corporations must now implement a concert process with all the stakeholders. The aim is to define with them an operating process which will satisfy all the interests at stake. The capacity of the organisation to ensure its own development on the long term will depend on the quality of the relationships set between these stakeholders. There is thus a double object to this contribution. First the need to take into account the stakeholders' expectations, especially in the ecological and social fields, will be shown. Secondly, the part played by a relational approach in the success of a sustainable strategy will be demonstrated. [PUBLICATION ABSTRACT]
Postal privatization and the transformation of the global logistics industry
Authors: HICKEY Robert
Published: March 2024

The global trend to privatize and deregulate national postal services has grown rapidly in the past several years. The process of privatization of the US Postal Service presents an interesting case in which the world's largest national post has privatized significant portions of its collection and sortation network. This paper examines the influence of corporate interests and business strategies on the privatization process of the US postal sector. These changes are taking place in the context of transformative changes in the global logistics industry. Despite years of failed postal reform legislation, business strategies creating public-private partnerships have driven a unique form of postal privatization - one preferred by private businesses - privatization that constrains competition. [PUB ABSTRACT]
Premier référentiel de connaissances associées aux capacités organisationnelles de l'administration électronique
Authors: SAINT-AMANT Gilles E. , RENARD Laurent
Published: March 2024

In this article, we present an initial knowledge repository associated with the organizational capabilities of E-government. First, we define the concepts of organizational capability and knowledge repository. Second, we explain the procedures that researchers followed to develop this initial knowledge repository, that is the research objectives, the research question, and the methodology followed. Third, we present in detail the knowledge repository associated with the organizational capabilities of E-government. This knowledge repository is made up of an E-government evolution model, a conceptual modelling of the associated organizational capabilities, disciplines, and knowledge domains, a maturity model to assess organizational capabilities, and a management model for the development of the knowledge repository and of organizational capabilities. Finally, we discuss the limitations of this initial knowledge repository, especially the issue of placing it in context, which will enrich the codified knowledge from feedback linked to the implementation of E-government projects. In a next stage, the researchers will test empirically this initial knowledge repository to verify its operational validity. [PUBLICATION ABSTRACT]
Mối liên hệ giữa con đường truyền tín hiệu interleukin-6 với quá trình xâm lấn và di căn của tế bào ung thư-liệu pháp điều trị ung thư hướng đích
Authors: Lê Hương Ly  , Trần Thị Thúy Nga  , Nguyễn Thị Thu Trang  , Trần Quế Hương
Published: March 2024

IL-6 là một cytokin quan trọng liên quan đến điều hòa miễn dịch và viêm, đóng một vai trò không thể thiếu trong một số hoạt động quan trọng của cơ thể, góp phần đáp ứng miễn dịch, phát triển mô và cân bằng nội môi. Trong các bệnh ung thư, nồng độ IL-6 tăng cao tác động đến sự phát triển liên tục của khối u và tăng khả năng đề kháng. Tiên lượng lâm sàng kém ở nhiều loại ung thư được chứng minh có liên quan đến hoạt động quá mức của đường truyền tín hiệu IL-6/JAK/STAT3. Trong môi trường vi mô khối u (TME), tín hiệu IL-6/JAK/STAT3 thúc đẩy sự tăng sinh, sống sót, xâm lấn và di căn của các tế bào khối u, đồng thời ngăn chặn mạnh mẽ phản ứng miễn dịch chống khối u. Nhắm mục tiêu đường truyền tín hiệu IL6 đang được nhiều nhà nghiên cứu quan tâm, điển hình như kháng thể đơn dòng kháng IL-6, tocilizumab cho thấy hiệu quả lâm sàng đầy hứa hẹn. Ngoài ra, bazedoxifen và tofacitinib cũng được công nhận như những thuốc phân tử nhỏ ức chế IL6 tiềm năng.Trong bài tổng quan này, chúng tôi tóm tắt vai trò của đường truyền tín hiệu IL-6 trong sinh học ung thư, nhấn mạnh vào khả năng xâm lấn và hình thành di căn. Hướng mục tiêu vào các thành phần chính như IL-6, IL-6R, gp130, STAT3 và JAK để thảo luận chuyên sâu về tiềm năng vượt trội của chất ức chế tín hiệu IL-6.
Analysis of Growth Ratio, Effectiveness Ratio, and Efficiency Ratio in Bandung City
Authors: Rusdi Renovita , Herawati Olis , Digdowiseiso Kumba
Published: March 2024

Regional financial performance reflects the quality of financial management performance in a region. This research aims to analyse the financial performance of the Bandung City Government for the 2018-2022 budget year. The analysis was carried out by calculating the growth, effectiveness, and efficiency ratios based on the figures presented in the Bandung City APBD Budget Realization Report. This research uses quantitative descriptive analysis methods. The results of this research show that the financial performance of the Bandung City Government using the growth ratio is still not optimal because in 2020 there was a significant decline. The effectiveness ratio in 2018 and 2019 was categorised as less effective and experienced considerable development from 2020 to 2022 to the practical category. The efficiency ratio is classified as less efficient because the average value for 2018-2022 is 98.91%. The efficiency ratio in 2018-2020 continued to decline to below 100%, but in 2021-2022, it increased again until it reached above 100%, which means it became inefficient.
Implementation of Job Training Program on Employee Performance at PT Worldwhite Enterprise Brand Prepp Studio
Authors: Musyaffa Fadhel , Pratama Muhammad Dzaqi , Digdowiseiso Kumba
Published: March 2024

This research discusses the implementation of job training programs on employee performance at PT World White Enterprise Brand Prepp Studio, a company operating in the creative industry. The main focus of this research is to analyze the effectiveness and impact of the training program that has been implemented by the company in improving employee skills and performance. This research methodology includes analysis related to training sourced from several previous studies. The research results show that the training program has made a positive contribution to increasing employee productivity and competency. With this program, employees are able to face work demands more efficiently and have a positive impact on the company's production results. In addition, this research also evaluates employee responses and perceptions of the training program, which can be a basis for improving and developing the program in the future. The implications of these findings can help PT World White Enterprise Brand Prepp Studio and similar companies to design more effective training programs, in accordance with industry needs and developments. This study provides insight into the importance of investing in human resource development to achieve competitive advantage in a dynamic business environment.
Financial Ratio Analysis of PT Bank Central Asia Tbk Period 2019 – 2022
Authors: Yeni Wa Ode Sri , Kristanti Yosephine , Digdowiseiso Kumba
Published: March 2024

The banking sector is a vital sector for the development of a country. To find out the company's performance, an analysis of the company's financial reports can be carried out, and the increases and decreases that occur can be used as an analysis for the company's future. The research results on the financial statements of PT Bank Central Asia Tbk for the 2019–2022 period show that total current assets will be higher than total short-term liabilities, so the quick ratio presentation will decrease. From a liquidity perspective, a bank's health is measured by its loan-to-deposit ratio. The solvency ratio shows that the company's results have increased yearly because the level of assets owned by the company is relatively high, and the initial capital tends to be small. This can result in the company's level of capital health being sufficient. The profitability ratio results show that the company gets high ROE and ROA results, so it can be interpreted that the net gain is relatively high.
Marketing Strategy in Increasing Sales of D'besto Products
Authors: Trilaksono Agung , Afifudin Zen , Digdowiseiso Kumba
Published: March 2024

Fried Chicken is a type of fast food that is popular with Indonesian people. The high public interest in fried chicken creates promising business opportunities for business people. D'Besto is known to the public for its various menu variants, easy to find and affordable prices. This research is based on the company's strategy to increase sales by implementing various methods to generate and increase profits. Companies face various obstacles in maintaining and improving their business by overcoming their shortcomings, so that they can continue to innovate in development in order to maintain their characteristics, and to increasingly gain advantages over competitors. This research aims to determine the marketing strategy carried out by D'Besto in marketing and increasing sales of its Fried Chicken products. The research method used is qualitative with a case study approach to the D'Besto business. Data were collected using in-depth interviews with 2 informants consisting of 1 D'Besto owner and 1 D'Besto Engagement Manager employee. This research aims to determine the advantages and disadvantages of D'Besto's marketing strategy. This research uses a qualitative research approach. The data sources used are primary data and secondary data. Data collection techniques through interviews, observation and documentation. As well as using data analysis techniques and checking the validity of the findings. The research results show that marketing strategies to increase sales at D'Besto can be achieved by implementing the Marketing Mix 7P (Product, Price, Place, Promotion, People, Process, Physical Evidence) and SWOT Analysis (Strengths, Weaknesses, Opportunities, and Threats).
Product Diversification and Strategy Implementation Public Relations in Setu Babakan
Authors: Pradini Gagih , Awaloedin Dipa Teruna , Saleh Muhammad Surya , Andini Davi Ayu
Published: March 2024

Tourism faces the challenge of innovation and diversification to attract a varied audience. This study focuses on the role of Public Relations (PR) in promoting product diversification, particularly in cultural, culinary, and interactive experiences. Setu Babakan, a cultural destination in Jakarta, serves as the case study. The research utilizes qualitative methods, emphasizing observation and interviews, to explore the diversification potential and implementation of PR strategies. The study applies SWOT analysis for comprehensive strategic planning, addressing internal strengths and weaknesses, along with external opportunities and threats.
5G Technology Transformation In Tourism
Authors: Pradini Gagih , Awaloedin Dipa Teruna , Agustiani Fitri , Kelly Ahmad
Published: March 2024

The transformation of 5G technology has significantly impacted various aspects, including the tourism industry. With much higher speed and capacity than previous technologies, 5G enables the creation of more immersive and connected tourism experiences. Purpose This study explores the impact of implementing 5G technology on the tourist experience in certain destinations. Specific objectives include: Explain changes in the traveller experience following the implementation of 5G technology. Identify factors influencing traveller perception and satisfaction related to applying 5G technology. Analyse the challenges and opportunities of adopting 5G technology in the tourism sector. This research method uses a descriptive qualitative approach and SWOT analysis.
Roh Kudus dalam Misi Penginjilan: Sebuah Refleksi Teologi Biblikal
Authors: Kristiono Steve Alpha Yani
Published: March 2024

Penginjilan merupakan salah satu bagian dalam pelayanan sebagai mandat Tuhan yang tertulis melalui Firman-Nya, “pergilah dan jadikanlah semua bangsa murid-Ku…”. Setiap orang percaya telah diberikan seorang Penolong yaitu Roh Kudus. Peran Roh Kudus dalam pemberitaan Injil tidak dalam dilepaskan dari dasar Alkitab (Lukas 24: 49) dan (Kisah Para Rasul 1:8). Gereja atau orang percaya menerima baptisan untuk diperlengkapi dengan kuasa Allah dalam memberitakan Injil. Alkitab menjelaskan bahwa Roh Kudus memberikan kuasa bagi setiap orang untuk memberikan kesaksian di seluruh muka bumi. Gambaran permasalahan dalam penulisan ini ialah bagaimana konsep Alkitab tentang peran Roh Kudus dalam pelayanan penginjilan? Tujuan penelitian ini adalah untuk memaparkan tinjauan teologis tentang peran Roh Kudus dalam penginjilan. Adapun metode yang digunakan penulis adalah dengan melakukan studi literatur melalui sumber buku dan jurnal-jurnal teologi yang disatukan menjadi sebuah uraian yang baik. Hasil dan simpulan dari penulisan ini ialah Alkitab menegaskan bahwa Roh Kudus berperan penting dalam pelayanan penginjilan, dalam memberikan kuasa atas orang percaya. Peranan Roh Kudus terjadi secara aktif, dinamis dan sampai akhir, sehingga orang-orang tebusan-Nya menerima kehidupan kekal.
Uticaj migratornih kretanja na tržište rada u zemljama Zapadnog Balkana
Authors: Maksimović Marijana , Nikolić Ivan
Published: March 2024

Migracije su danas jedna od najaktuelnijih tema u svetu. Najčešći razlozi nastanka su ratovi, zatim, to mogu biti klimatske promene, a postoje i migracije nastale iz ekonomskih razloga, i njihov cilj je potraga za boljom materijalnom egzistencijom, ostvarivanje višeg životnog standarda, bolji uslovi zapošljavanja, obrazovanja, a samim tim i bolji uslovi života. Predmet ove analize su ekonomske migracije i savremena migraciona kretanja, tj. useljavanje i iseljavanje stranaca u zemlje Zapadnog Balkana (ZB). Makroekonomski pokazatelji ukazuju na stabilizaciju na tržištu rada u drugoj deceniji XXI veka, mada ekonomije stagniraju. Postavlja se pitanje da li je to posledica veće stope privrednog rasta ili su indukovani depopulacijom i redukcijom radno aktivnog stanovništva? Cilj rada je da se ukaže na neophodnost upravljanja migracionim tokovima u ovim zemljama i potrebe za usmeravanjem migranata na tržištu rada. Rad se sastoji iz dva dela. U prvom delu se daje pregled dosadašnjih istraživanja o migracijama, pojmu i vrstama migracija. Drugi deo rada se sastoji iz empirijske analize migracija u zemljama Zapadnog Balkana i Srbije i njihovom uticaju na tržište rada i privredni razvoj.
Response to Dabrafenib Plus Trametinib in a Patient With an Uncommon Activating BRAF Mutation: A First in Non–Small Cell Lung Cancer
Authors: Sharp John A. , Jones Daniel , Rotow Julia K. , Fidias Panos M. , Bertino Erin , Owen Dwight H.
Published: March 2024

Mutations in BRAF are present in 4% of non–small cell lung cancer (NSCLC), of which half are well-characterized activating variants affecting codon 600 (classified as class I). These mutations, most commonly BRAF V600E, have been associated with response to BRAF/MEK-directed small molecule kinase inhibitors. NSCLC with kinase-activating BRAF mutations occurring at other codons (class II variants) represent a substantial portion of BRAF-mutated NSCLC, but use of targeted therapy in these tumors is still under investigation. Class II mutations have been described in other tumor types and have been associated with response to BRAF/MEK-targeted agents, although optimal treatment strategies for these patients are lacking. This report presents a case of a woman with metastatic NSCLC harboring a class II BRAF p.N486_P490del variant who had a sustained clinical response to combination therapy with dabrafenib and trametinib. This first report of the use of BRAF/MEK-targeted therapy for this variant in NSCLC supports consideration of such treatment for tumors with class II BRAF variants.
An updated analysis of the content and accessibility of hand surgery fellowship websites and fellowship directories
Authors: Wu Scott , Mehta Manish P , Ho Alisha A , Wun Kelly H , Gerlach Erik B , Carney John , Swiatek Peter R , Shah Chirag
Published: March 2024

Background

Recent changes to the hand surgery fellowship application process and

the pandemic-related transition to virtual interviews necessitate updated

analyses of fellowship websites’ and directories’ content and accessibility.

The study aims are to identify deficits in hand fellowship website and

fellowship directory content and accessibility and compare current

findings to those previously reported.

Methods

A list of all accredited hand fellowship programs was queried from the

ASSH fellowship directory in January 2022. Data for each program were

recorded on 38 metrics across four different categories: General

Overview, Accessibility Information, Educational Information, and

Recruitment Information. Fisher’s exact test was used to assess

differences between categorical variables. Unpaired t-test and analysis of

variance (ANOVA) were used to compare continuous variables for two or

more potential predictors, respectively.

Results

92 program websites were analyzed. Only 53 (58%) ASSH links and 12

(13%) FREIDA links directly connected users to the website, with no

improvement from prior investigation. Content accuracy was poor with

just 13% of websites containing updated interview date information and

11% listing obsolete paper application information. Of the 30 program

websites (33%) with supplemental application requirements listed, only

5 (17%) also listed these requirements on their corresponding ASSH

page. Mean educational and recruitment information scores were

6.8±2.1 and 5.0±1.5 out of 10, respectively.

Conclusions

Though improved, the accessibility, comprehensiveness, and accuracy of

information found on hand fellowship websites remains poor and

outdated. Educational content and recruitment content are largely

homogenous among programs.
Determinantes de la supervivencia de las microempresas en la ciudad de Riobamba
Authors: González Bautista María Gabriela , Auquilla Cayambe Danny , Villalva Moya Ronald , Alvarez Basantes Karina
Published: March 2024

El emprendimiento desempeña un papel fundamental en el desarrollo de una sociedad. En la ciudad de Riobamba desde enero de 2022 hasta julio de 2022 se iniciaron 683 negocios, pero 596 de ellos no lograron sobrevivir, se debe mencionar que el 78,90% de las empresas de esta ciudad son micronegocios. Por esta razón, esta investigación tuvo como objetivo identificar los factores que influyen en la supervivencia de las microempresas en la ciudad de Riobamba durante el año 2022. En primer lugar, se examinaron teorías como el capital humano de Schultz y el espíritu empresarial de Lazear. Luego, se llevó a cabo una encuesta a 221 microempresas, donde se recopiló información detallada de las mismas. Con base en la información primaria obtenida se desarrolló un modelo econométrico utilizando la metodología de Mínimos Cuadrados Ordinarios (MCO). Los resultados de esta modelización revelaron que los factores determinantes para la supervivencia de las microempresas en la ciudad de Riobamba en el año 2022 eran: la edad del microempresario, el género, las actividades recreativas, la experiencia laboral previa en otras empresas antes de iniciar el negocio y el promedio de habilidades financieras y de gestión. Esta investigación ofreció una visión clara de los factores fundamentales que pueden influir en el éxito y la supervivencia de las microempresas en Riobamba. Además, brindó información de gran valor tanto para los emprendedores como para las políticas de desarrollo económico en la región.
MALADIE HEMORROIDAIRE TRAITEE PAR LA METHODE DE MILLIGANMORGAN A L’HOPITAL NATIONAL DONKA
Authors: SYLLA,et al... HAMIDOU
Published: March 2024

Introduction: Hemorrhoids are a common anorectal condition. Hemorrhoidectomy according to Milligan Morgan consists of the excision of varicose hemorrhoidal nodules. This technique is considered the “gold standard”. However, it is associated with significant postoperative morbidity. The aim of our study was to report our experience in the management of hemorrhoids treated according to Milligan, Morgan. Methodology: This was a retrospective, descriptive study over 3 years from January 1, 2015 to December 31, 2017. The patients treated by Milligan Morgan formed the study population. Our variables were epidemiological, therapeutic and prognostic. Results: we collected 2.76% (n=56) of patients treated by the Milligan Morgan technique of all hospitalizations (N=2,025). The average age was 45.3 years; extremes (24 and 85 years). The age group of 30 to 39 years was the most represented 37.5% (n = 21). Anal pain 100% (n=56), rectorrhagia 55.35% (n=31) and prolapse 44.64% (n=25) were the reasons found. The average duration of evolution was 4.13 years; extreme (0.16 and 31 years). The comorbidities were diabetes 12.5% (n= 7), hypertension 7.14% (n= 4) and HIV 5.35% (n= 3). More than fortyfour percent (n=25) were grade 3 hemorrhoids; 21.42% (n=12) grade 4 and 14.28% (n=8) grade 2 complicated by rectal bleeding. The postoperative course was simple in 80.35% (n=45). The postoperative complications encountered were urinary retention 10.71% (n=6), hemorrhage 7.14% (n=4), suppuration 7.14% (n=4) and constipation 1.78%. (n=1). Conclusion: despite the multitude of therapeutic techniques for hemorrhoids; Milligan-Morgan hemorrhoidectomy remains widely practiced due to the lower cost of the operation, and is the most effective treatment available in our practice setting. Key words: Hemorroidectomy, MilliganMorgan, Donka Hospital
INVAGINATION INTESTINALE AIGUË DE L’ADULTE : ASPECTS DIAGNOSTIQUES, THERAPEUTIQUES A PROPOS DE SEPT CAS DIAGNOSTIQUES AU CHU DE L’AMITIE SINO-CENTRAFRICAINE DE BANGUI, RCA
Authors: Ngboko, et al... Mirotiga Pétula Annicette
Published: March 2024

ABSTRACT Objective: To report the diagnostic and therapeutic difficulties of acute intussusception in adults in Bangui, Central African Republic. Patients and method: It was a retrospective descriptive study carried out in the general surgery department of Friendship Sino Centrafricaine University Hospital in Bangui. The reported data run from January 2019 to June 2023. It focuses on the records of adult patients of both sexes who underwent exploratory laparotomy for a bowel obstruction in which intussusception was diagnosed. Results: Intussusception accounted for 1.03% (N:7) of the 674 cases of acute bowel obstruction operated during the period. The mean age of patients was 32.8 years ± 9.7. Male subjects accounted for 57.14% (sex ratio = 1.33). At admission, five patients had occlusive syndrome and the other two had prolapse of a mass through the anus. Laparotomy was used to diagnose intussusception in all cases. These were ileoileal intussusception (57.1%), ileocecal (14.3%), colo-colic profunated by the anus (14.3%) and ileo-caeco-colic profunted by the anus (14.3%). Surgical procedures consisted of hail resection followed by termino-terminal anastomosis (42.8%), hail resection followed by ileocolic anastomosis (28.6%) and colonic resection, colostomy and restoration of delayed digestive continuity (28.6%).The histopathological study of the operating rooms had found chronic inflammation of the colonic mucosa (28.6%), colonic adenocarcinoma (14.3%), and adenomatous polyp (14.3%). In 3 patients aged 18, 22, and 29 years respectively no cause was found (42.8%). The postoperative follow-up was simple in all operated patients. Conclusion: Intussusception is a rare condition in adults. The diagnosis is often difficult and made on laparotomy. Practitioners' attention should be drawn to prolapsed masses in the anus in adults Keywords: Acute bowel obstruction, intussusception, surgery, Laparotomy, Central African Republic
ETUDE DE LA MORTALITE POST OPERATOIRE AU SERVICE DE CHIRURGIE GENERALE DU CHU DE L’AMITIE SINO-CENTRAFRICAINE A BANGUI, RCA
Authors: Doui, et al... Doumgba Antoine
Published: March 2024

SUMMARY Goal: To determine the postoperative mortality rate, identify the main causes and factors of postoperative morbidity and mortality in the general surgery department. Patients and method: This was a retrospective descriptive study covering the period from January 1, 2010 to December 31, 2019. The files of patients who died within 30 days following a surgical procedure were used. Results: A total of 812 deaths were recorded for 6,800 patients operated on in 10 years, or 11.9%. Only 200 files meeting the selection criteria were analyzed. The average number of deaths per year was 20 cases. The series included 63% male subjects. The average age was 41.4 years and the majority of deceased patients (51.5%) resided in Bangui. There were much more unemployed people (28%) and housewives (24.5%). Most deaths (82%) occurred after emergency surgery where acute generalized peritonitis (34%) and acute intestinal obstruction (25%) were the main indications. In 83% of cases, the deceased patients had a comorbidity, predominantly HIV infection (33.5%). The deceased patients were classified as ASA IV (45.5%) and Altémeier type III (34%). Postoperative deaths (80%) occurred in surgical intensive care 7 days on average after the operation following septic shock (55%). Conclusion: Post-operative mortality in Bangui remains high. It involves emergency surgery. The reorganization of emergency and surgical resuscitation services will help reduce this mortality rate. Keywords: Surgery, Surgical emergencies, postoperative mortality, Resuscitation, Central African.
PRISE EN CAHRGE D’UN CANCER CANALAIRE INVASIF DU SEIN CHEZ UN HOMME DE 61 ANS A L’HOPITAL GYNECO-OBSTETRIQUE ET PEDIATRIQUE DE YAOUNDE : DIFFICULTES THERAPEUTIQUES
Authors: NGAHA YANEU, et al... Junie
Published: March 2024

Introduction: Breast cancer, the leading malignant pathology in women, is still relatively rare in men. It accounts for less than 1% of malignant diseases in Men. Management strategies of breast cancer in males are copied from that of breast cancer in females. These therapies in men are in the experimentation stage despite the peculiarities observed. Hence, we are reporting the diagnosis and multidisciplinary management of a case of Invasive Ductal Carcinoma. Case presentation: we report the case of a 61-year-old male who consulted for a lump in the right breast discovered 3 years ago. Physical examination revealed an indurated nodular plaque (4x4x3cm) of the right breast located in the upper outer quadrant, not very tender not adherent to the superficial fascia. The overlying skin was macroscopically normal. Axillary palpation revealed homolateral axillary lymph nodes. The tumor was classified T2N1Mx. A breast ultrasound done revealed a lump of the right breast classified ACR4. Fine needle aspiration of the nodule as well as micro biopsy evoked an invasive grade 2 carcinoma. Neoadjuvant chemotherapy was done with cyclophosphamide. A right total Madden Mastectomy with homolateral lymphadenectomy was done. Progress postoperative was marked by local recurrence. Treatment with hormone therapy was initiated and radiotherapy delayed after secondary excision. We intended to show that tumor size, lymph node involvement and absence of hormone receptors are elements of poor prognosis just as a delay in radiotherapy is a risk for local recurrence. Conclusion: Male breast cancer is a rare pathology. Its management is copied exactly from that of the woman. Poor prognostic factors are: the size of the tumor, the presence of lymph nodes and the absence of hormone receptors. Keywords: breast cancer, male, prognosis, mastectomy, challenges
HERNIES POST-TRAUMATIQUES DITES GUIDON A PROPOS DE DEUX OBSERVATIONS. EXPERIENCE DE L’HOPITAL DE DISTRICT SANITAIRE DE TESSAOUA/MARADI/NIGER
Authors: BOUKARI, et al... MAMAN Haboubacar
Published: March 2024

Abstract Handlebar hernias or “handbar hernias” are hernias of the abdominal wall resulting from direct trauma to the anterior abdominal wall.. Hernia through the abdominal wall usually occurs as a result of trauma with seat belts, motorcycles, bicycle handlebars, etc. They usually occur at weak anatomical locations in the abdominal wall. These traumatic hernias are rare, requiring a high index of suspicion for clinical diagnosis. Observation. They were two patients aged 14 and 45 years old, received in surgical consultation for left paraumbilical swelling. The anamnesis revealed a notion of a fall on a bicycle handlebar with direct landing on the left side. The clinical examination objectified a swelling of the left flank, painless, reducible, impulsive and expansive with the effort of coughing. The diagnosis of a handlebar hernia was made and a midline laparotomy indicated. The surgical intervention had made it possible to discover a parietal defect for the two patients, a parietal repair was carried out. Conclusion. A hernia handlebar when it is simple its discovery can be late, exposing to the risk of strangulation. Hence the importance of a well-directed questioning and a meticulous physical examination. Keywords: Hernia; Handlebar; Trauma.
LONG-TERM RISK OF CHRONIC AND END-STAGE KIDNEY DISEASE AFTER PREECLAMPSIA: SYSTEMATIC REVIEW
Authors: Azwar Aziz Mohamad , Intan Kania Yulia , Aziz Ilham , Sibli
Published: March 2024

Introduction: Preeclampsia (PE) is a pregnancy-related syndrome, and its diagnosis has evolved to consider factors like hypertension and kidney involvement, with serum creatinine gaining importance. Despite the traditional view of PE as transient and reversible kidney disease, recent studies link it to long-term risks, including cardiovascular and renal diseases. The systematic review, "Long-Term Risk of Chronic and End-Stage Kidney Disease After Preeclampsia," aims to gather updated information from recent studies, focusing on ESRD, CKD, and kidney-related morbidity after PE. The goal is to inform the formulation of effective long-term control and prevention strategies for CKD associated with a history of preeclampsia.
Method: The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.
Result: This systematic review investigated final 16 articles. After looking at the titles and summaries, we found 8  papers that fit our criteria. At first, we excluded several articles because they were written in review style and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included a nation-wide cohort, nationwide register based cohort study, observational cohort study, population-based nested case-control study, and longitudinal cohort study.
Conclusion: Our study reveals a significant long-term impact of preeclampsia on kidney health, with a 5-fold higher risk of end-stage kidney disease (ESKD) for affected women. Ongoing clinical monitoring and further research are crucial to identify high-risk individuals, understand underlying mechanisms, and establish optimal follow-up and intervention strategies.
THE ROLE, FUNCTION, AND APPLICATION OF TECHNOLOGIES IN ARCHAEOLOGY: DATA FROM NW BELIZE
Authors: Neuhoff-Malorzo Patricia , Locker Angelina , Beach Timothy , Valdez Jr. Fred
Published: March 2024

The Programme for Belize Archaeological Project (PfBAP), in NW Belize, has recently benefitted from the application of several technologies not often available to archaeology research programs. The use of non-destructive geo-physical and related technologies at several sites has provided the PfBAP with data concerning community structure. These data also inform the interest for future excavations. The developments in isotope research have also benefitted the PfBAP in providing measures for understanding population movement and possible interaction across the NW Belize region. The local variation of strontium and oxygen isotopes in NW Belize is now better understood. The isotope data, from the PfBAP, demonstrates the presence and consistency of immigrants within ancient Maya settlements from NW Belize through time. A third technology that has modified the PfBAP understanding of ancient settlement and activity is the use of LiDAR. Ancient Maya settlements not previously recorded are now more evident as are features from ancient activities including reservoirs, sacbeob, and agricultural fields. The rapid changes in certain technologies and their application to archaeology are seen as beneficial in NW Belize.
INSULA SAHALIN DE CEHOV: O DESCINDERE ÎN INFERNUL UNEI COLONII PENITENCIARE
Authors:   Universitatea din București, RACOVIȚĂ OANA-MARIA
Published: March 2024

The purpose of this article is to analyze Anton Pavlovich Chekhov’s attitude towards the penal colony established on Sakhalin Island and how it fails to respect the human dignity of women and children within the island’s population. In this analysis I have referred to Chekhov’s text, Sakhalin Island, and to the reality captured by the writer following his visit to the island. This work differs considerably from Chekhov’s literary oeuvre, as it serves not only as a monograph on the island of Sakhalin, but also captures important autobiographical elements that subsequently altered Chekhov’s attitude to society. In the present paper I will also refer to the idea of colonialism within the Russian Empire, especially as it applies to the penal colony established on the island.
ROMANUL RUS DIN SECOLUL AL XIX-LEA ȘI DINAMICA LITERATURII ARGENTINIENE. STUDIU DE CAZ: TUNELUL DE ERNESTO SÁBATO
Authors:   Universitatea din București, LOZINSCHI SERGIU
Published: March 2024

With the publishing of the novel The Tunnel (1948), Sábato became the first Latin American writer to gain popularity in Europe and the most important representative of Existentialism in Latin America. In this paper we investigate the intertextual ties between Sábato’s text and important Russian novels of the XIX century as a means to highlight their original and innovative assimilation into the Argentinian literary tradition and the role they played in the creation of this geographical and cultural area’s literary canon. This investigation intends to systemize the variety of Russian literary models in the novel The Tunnel.
CEHOV ÎN GRĂDINĂ: AVATARURI ALE SPAȚIULUI ÎN CĂLUGĂRUL NEGRU
Authors:   Universitatea din București, BLAGA OCTAVIA-ANA
Published: March 2024

If he weren't an excellent writer, Chekhov could have been an equally great gardener. The writer reflected on this idea in a letter to Mikhail Menshikov dated February 20, 1900. From the moving descriptions of the hills full of lilac in The Steppe (1887) to the desperate attempts of a family to save their orchard in The Cherry Orchard (1904), nature disturbed or completed by man is a common occurrence in Chekhov’s writing. We will attempt to read Chekhov’s natural space using filters of spatial theory (or its contingents), focusing on the garden in “The Black Monk”. We will strive to understand Chekhov's text through Foucault’s concept of heterotopia, as well as Hone’s interspaciality, while also looking at it through Soja’s theory of the three spaces, derived from the spatial perceptions proposed by Lefebvre, in an attempt to understand the multiple meanings of Pesotsky’s garden.
SOSIALISASI PENYUSUNAN LAPORAN LABA RUGI SEDERHANA BAGI KELOMPOK USAHA MIKRO KECIL DAN MENENGAH PADA UMKM GADING BERSINAR
Authors: Soeparyono Regina Deia , Khuluqi Khusnul , Sugeng Andry
Published: March 2024

The profit and loss report is part of a company's financial report produced in an accounting period which describes the elements of the company's income and expenses to produce a net profit (or loss). MSMEs are independent productive economic enterprises, usually carried out by individuals or business entities that are not subsidiaries or branches of companies owned, controlled or part of directly or indirectly. Business actors in the Gading Shining UMKM are part of the UMKM. The problem faced by MSME actors is related to the inability of MSME actors to prepare profit and loss reports for their businesses. MSME players claim that they do not have knowledge regarding making profit and loss reports. This Community Service activity aims to prepare a simple profit and loss report for Gading Bersinar MSME players so that it can be used to manage and build MSMEs and collaborate with bankers, investors and other business partners. The method developed in this activity involves socializing the preparation of simple profit and loss reports for Gading Bersinar MSMEs. So with this activity regarding the socialization of simple profit and loss reports, it is intended to provide understanding in making simple profit and loss reports for ivory shining MSME players so that they can be directly applied in their businesses.
Electoral Reforms in Pakistan During the PPP 4th Regime and Its Implementation Status: A Reappraisal
Authors: Gohar Shaista , Khan Yunus , Gul Shehla
Published: March 2024

Elections are an essential element of modern democracy. For fair, free and transparent elections conduction, electoral reforms are necessary. However, the implementation and enforcement of these electoral reforms are more important, and for implementation of continuity of democratic transition is of far greater importance. This paper attempted to highlight electoral reforms, both in law and constitution, made during the 4th regime of the Pakistan People’s Party. This brief paper investigates to what extent the constitutional amendments brought the election process in line. The paper also points out the implementation of these renewed efforts of election reforms in the 2013 general elections. This paper will be beneficial for scholars, Political Science and Pakistan Studies students and researchers. Data is mostly collected through secondary sources like books, journal articles, reports and reliable newspapers articles. For data application, the qualitative method is selected. The descriptive model of research is used to describe the facts of electoral reforms in Pakistan during the 4th regime of the PPP and its implementation in the 2013 general elections. The electoral reforms in Pakistan during the PPP government (2008-2013) did not guarantee good results; however, its implementation and enforcement in the 2013 elections are important.
Perancangan Multimedia Interaktif Mengenal Sejarah Tradisi Tarian Barongsai
Authors: Iskandar Riki , Usman Robby
Published: March 2024

Perancangan Multimedia Interaktif Mengenal Sejarah Tradisi Tarian Barongsai ini dilatarbelakangi karena banyaknya masyarakat khususnya remaja keturunan Tionghoa di kota Padang yang tidak mengetahui sejarah dari barongsai. Perancangan ini bertujuan untuk menjaga tradisi tarian barongsai agar tidak hilang. Tahap selanjutnya yang dilakukan adalah mengumpulkan data berupa data verbal dan visual. Pengumpulan data verbal dilakukan dengan melakukan observasi ke lapangan dan mewawancarai narasumber untuk mendapatkan informasi tambahan mengenai sejarah barongsai. Data visual yang dikumpulkan berupa foto dokumentasi dari tempat penyimpanan barongsai di perkumpulan Tionghoa kota Padang. Setelah data dikumpulkan dilakukan analisis masalah atau data yang didapat dengan menggunakan Analisis SWOT dan 5W1H untuk mengetahui dan memfokuskan target yang ingin dicapai. Setelah melakukan analisis masalah, dilakukan proses perancangan untuk menghasilkan solusi dari masalah yang ditemukan. Dalam perancangan multimedia interaktif ini, dilakukan dengan menambahkan ilustrasi, animasi dan warna- warna yang menarik dan mencirikan kebudayaan Tionghoa. Selanjutnya multimedia interaktif ini di burning ke sebuah CD dan dijual saat ada event- event yang bernuansa Tionghoa.
Penerapan Data Mining Untuk Peringatan Dini Banjir Menggunakan Metode Klastering K-Means (Studi Kasus Kota Padang)
Authors: Nozomi Irohito
Published: March 2024

Bencana banjir sering terjadinya di wilayah Indonesia, salah satunya adalah Kota Padang. Dengan keadaan cuaca yang sering berubah, maka sulit memperdiksi apakah cuaca tersebut berpotensi banjir atau tidak. Sistem peringatan dini ini merupakan salah satu bentuk manajemen penanganan bencana yang bertujuan mengambil tindakan yang cepat dan tepat dalam memprediksi banjir  dengan menggunakan teknik Data Mining. Penelitian ini merupakan proses untuk memprediksi bencana banjir dengan menggunakan metode Klastering K-Means. Data yang didapat dari BMKG dikelompokkan menjadi satu atau lebih cluster dan kemudian diolah. Analisis dan pengolahan data menggunakan tools RapidMiner v.5.3. Hasil dari penelitian ini didapatkan cluster yang menjadi tingkatan bahaya bencana banjir yang terdiri dari tingkatan rendah, tingkatan sedang, dan tingkatan tinggi.
Perancangan Sistem Inventory Untuk Stok Barang Herbisida Pada UD. Anugrah Jaya Tani Dengan Bahasa Pemrograman PHP dan Database MySql
Authors: Amelia Sari Lubis Fitri , Sahara Lubis Siti , Hendrik Billy
Published: March 2024

Advances in information and communication technology are growing rapidly in all directions so that a lot of information is produced from technology and is applied in various fields. In the field of information technology, an inventory system is also needed which is used to view the stock of goods at UD. Anugrah Jaya Tani. UD. Anugrah Jaya Tani is a kiosk that sells various herbicides. The use of chemical herbicides is intended so that they do not affect cultivated plants but affect the growth of weeds. Therefore, it takes herbicides or substances that are selective and precise in controlling weeds. Inventory systems are one of the parts that can also be developed with the existence of internet resources. The internet can play a role in facilitating activities. This is because inventory activities require communication between the parties involved in this matter. The purpose of using an inventory system where the most basic is being able to align customer demand with existing supply or control existing inventory. The results of this study are to determine the amount of stock of goods to be marketed, create a system that can be accessed by anyone, and create an attractive consultation layout. Inventory is storage owned by a company to be traded or used for company operations. All items are referred to as an inventory system, depending on the type of the Company's business