bluuebunny/crossref_metadata_2025 huggingface dataset:
The music-related quality of life: Italian validation of MuRQoL into MUSQUAV questionnaire and preliminary data from a cohort of postlingually deafened cochlear implant users
Authors: Frosolini A. , Parrino D. , Mancuso A. , Coppola N. , Genovese E. , de Filippis C.
Published: January 2022

Purpose

Cochlear implant (CI) users do not receive much of the auditory information necessary for an accurate perception of music. This usually entails a dissatisfaction with the music they hear, so that their quality of life may potentially be affected. The main aim of this paper was to translate and validate into Italian an instrument to evaluate these aspects—The Music-Related Quality of Life Questionnaire (MuRQoL)—to help the work of clinicians and therapists.

Methods

The translation of the MuRQoL into “Questionario Musica e Qualità della Vita” (MUSQUAV) was done according to the international guidelines. The translated questionnaire was administered to normal hearing (NH) and CI users adults. Exploratory factor analysis, confirmatory factor analysis and known group method were used to confirm construct validity and applicability of MUSQUAV.

Results

We retrieved 225 results. The MUSQUAV questionnaire was acceptable according to the goodness-of-fit indices. The correlation between the items, evaluated using Cronbach’s α coefficient, indicates a good internal consistency (> 0.80). The non-parametric Mann–Whitney test showed significant differences in the distinct populations tested.

Conclusions

The MUSQUAV questionnaire is a valid, low-cost and rapid instrument for professional workers in the audiological field, especially useful in the assessment of the patients' perception and musical engagement.
Visual hallucinations in Lewy body disease: pathophysiological insights from phenomenology
Authors: D’Antonio Fabrizia , Boccia Maddalena , Di Vita Antonella , Suppa Antonio , Fabbrini Andrea , Canevelli Marco , Caramia Francesca , Fiorelli Marco , Guariglia Cecilia , Ferracuti Stefano , de Lena Carlo , Aarsland Dag , ffytche Dominic
Published: January 2022

Visual hallucinations (VH) in Lewy body disease (LBD) have a heterogenous phenomenology classified into minor phenomena (MVH) and complex hallucinations (CVH). Mechanisms underpinning VH and their temporal aspects are largely unknown. According to the hodotopic model, we investigated whether changes in distinct cognitive domains and neural networks in the hallucination trait underpin temporal aspects of MVH and CVH in the hallucination state. 35 LBD patients with VH underwent a complete neuropsychological evaluation and resting-state fMRI. North-East-Visual-Hallucinations-Interview was used to assess their typical VH content, duration, and frequency. We found that MVH was not associated with cognitive impairment, while CVH was associated with impairments in visuoperceptual processes, attention and visual abstract reasoning. In seed-to-seed functional connectivity (FC) analysis we identified functional couplings associated with MVH and CVH temporal severity (duration x frequency), duration and frequency. MVH severity was negatively associated with FC between early visual areas (EVA) and ventral-visual-stream regions, and negatively associated with FC between brainstem and EVA, which may be linked to LBD brainstem neuropathology. CVH duration was positively associated with FC between ventral-visual stream and salience network (SN). CVH frequency was negatively associated with FC between DMN and SN. Functional alterations in distinct visual and attentional networks and their dynamic interaction in trait LBD hallucinators are linked to both the phenomenology of state content and its temporal characteristics. Within a network, VH frequency and duration may be linked to different types of functional alterations: increased connectivity leading to sustained activity prolonging VH (duration) and decreased connectivity increasing dysregulated, spontaneous activity (frequency). These findings support the hodotopic hypothesis of VH and may reflect a link between VH phenomenology, LBD neuropathological progression and the involvement of specific neurotransmitter systems.
Diagnosis of atypical carcinoid can be made on biopsies > 4 mm2 and is accurate
Authors: Reuling Ellen M. B. P. , Naves Dwayne D. , Daniels Johannes M. A. , Dickhoff Chris , Kortman Pim C. , Broeckaert Mark A. M. B. , Plaisier Peter W. , Thunnissen Erik , Radonic Teodora
Published: January 2022

In the 2021 WHO thoracic tumors, gradation of lung carcinoids in biopsies is discouraged. We hypothesized that atypical carcinoid (AC) could be reliably diagnosed in larger preoperative biopsies. Biopsy-resection paired specimens of carcinoid patients were included, and definitive diagnosis was based on the resection specimen according to the WHO 2021 classification. A total of 64 biopsy-resection pairs (26 typical carcinoid (TC) (41%) and 38 AC (59%)) were analyzed. In 35 patients (55%), tumor classification between the biopsy and resection specimen was concordant (26 TC, 9 AC). The discordance in the remaining 29 biopsies (45%, 29 TC, 0 AC) was caused by misclassification of AC as TC. In biopsies measuring < 4 mm2, 15/15 AC (100%) were misclassified compared to 14/23 AC (61%) of biopsies ≥ 4 mm2. Categorical concordance of Ki-67 in biopsy-resection pairs at threshold of 5% was 68%. Ki-67 in the biopsy was not of additional value to discriminate between TC and AC, irrespective of the biopsy size. Atypical carcinoid is frequently missed in small bronchial biopsies (< 4 mm2). If the carcinoid classification is clinically relevant, a cumulative biopsy size of at least 4 mm2 should be considered. Our study provides strong arguments to make the diagnosis of AC in case of sufficient mitosis for AC on a biopsy and keep the diagnosis “carcinoid NOS” for carcinoids with ≤ 1 mitosis per 2 mm2. Ki-67 has a good concordance but was not discriminative for definitive diagnosis.
Some geometric inequalities for varifolds on Riemannian manifolds based on monotonicity identities
Authors: Scharrer Christian
Published: January 2022

Using Rauch’s comparison theorem, we prove several monotonicity inequalities for Riemannian submanifolds. Our main result is a general Li–Yau inequality which is applicable in any Riemannian manifold whose sectional curvature is bounded above (possibly positive). We show that the monotonicity inequalities can also be used to obtain Simon-type diameter bounds, Sobolev inequalities and corresponding isoperimetric inequalities for Riemannian submanifolds with small volume. Moreover, we infer lower diameter bounds for closed minimal submanifolds as corollaries. All the statements are intrinsic in the sense that no embedding of the ambient Riemannian manifold into Euclidean space is needed. Apart from Rauch’s comparison theorem, the proofs mainly rely on the first variation formula and thus are valid for general varifolds.
A multidimensional framework for assessing adaptative justice: a case study of a small island community in the Philippines
Authors: See Justin , Wilmsen Brooke
Published: January 2022

Island communities are the targets for a wide range of interventions designed to help them adapt to climate change. A growing body of research explores the equity and justice implications of adaptation policies and programmes, revealing they often exacerbate, rather than alleviate, inequality within at-risk communities. This paper pushes beyond existing understandings of climate justice, which prioritise its distributive and procedural aspects. Through household surveys, interviews and participant observation, the paper presents a case study of a major adaptation project in a small island community in the Philippines, paying particular attention to its equity implications at the local level. It describes how local politics and power relations distorted the well-intentioned aims of the project and resulted in the project exacerbating, rather than alleviating, pre-existing inequality. Climate change adaptation is a deeply political process that is easily subverted by the interests of the powerful. To mitigate the influence of power and politics in future climate adaptation projects, we present an expanded multidimensional framework for assessing adaptative justice that incorporates the neglected aspects of recognition and structure.
How Expectations Shape the Formation of Intrusive Memories: An Experimental Study Using the Trauma Film Paradigm
Authors: Herzog Philipp , Barth Charlotte , Rief Winfried , Brakemeier Eva-Lotta , Kube Tobias
Published: January 2022

Background

Although intrusions are the hallmark symptom of posttraumatic stress disorder, there is still limited knowledge about the processes that contribute to the development of intrusions. Here, we used the well-established trauma film paradigm (TFP) to investigate how expectations about the intensity and controllability of intrusions influence their occurrence.

Methods

90 healthy participants underwent the TFP before they were randomized to one of three conditions manipulating their expectations about intrusions: positive expectations group; negative expectations group; control group. The primary outcome was the frequency and severity of intrusive memories as assessed with an intrusion diary over seven days.

Results

The TFP was well implemented, as indicated by significant post-film anxiety and a substantial number of intrusions reported for the subsequent week. The three groups did not differ in their expectations about intrusions and, relatedly, in their experience of intrusions. A mediation analysis revealed that the influence of post-film anxiety on intrusive memories was fully mediated by expectations.

Conclusions

Despite the failure of the expectation manipulation, the results of the mediation analysis support the hypothesis that post-film expectations influence the formation of intrusive memories, suggesting that intrusions may result from maladaptive dynamics between emotional and cognitive processes following trauma(like) experiences.
Effects of Parental Involvement in Robot-Assisted Autism Therapy
Authors: Amirova Aida , Rakhymbayeva Nazerke , Zhanatkyzy Aida , Telisheva Zhansaule , Sandygulova Anara
Published: January 2022

Parental involvement in traditional autism therapy is key to the effective treatment of children with ASD. Little is known about parental involvement in robot-assisted autism therapy (RAAT)—novel therapeutic support for children with ASD. Our study investigates the effect of parental presence on multiple-session RAAT conducted with 16 children with ASD. They interacted with the social robot in the presence or absence of their parents. We measured children's socio-behavioral outcomes and conducted semi-structured interviews with parents. Parents did not necessarily affect the children's outcomes during the interventions. However, children’s autism-related symptoms resulted in different socio-behavioral outcomes between sessions with and without parents. Most parents have reported positive changes in their children's behaviors when interacting with the robot.
Biological computation: hearts and flytraps
Authors: Kirkpatrick Kay L.
Published: January 2022

The original computers were people using algorithms to get mathematical results such as rocket trajectories. After the invention of the digital computer, brains have been widely understood through analogies with computers and now artificial neural networks, which have strengths and drawbacks. We define and examine a new kind of computation better adapted to biological systems, called biological computation, a natural adaptation of mechanistic physical computation. Nervous systems are of course biological computers, and we focus on some edge cases of biological computing, hearts and flytraps. The heart has about the computing power of a slug, and much of its computing happens outside of its forty thousand neurons. The flytrap has about the computing power of a lobster ganglion. This account advances fundamental debates in neuroscience by illustrating ways that classical computability theory can miss complexities of biology. By this reframing of computation, we make way for resolving the disconnect between human and machine learning.
A comparative analysis of two immersive virtual reality systems in the integration and visualization of natural hand interaction
Authors: Molina Guillermo , Gimeno Jesús , Portalés Cristina , Casas Sergio
Published: January 2022

It is generally accepted that the use of natural interaction provides a positive impact in Virtual Reality (VR) applications. Therefore, it is important to understand what is the best way to integrate and visualize this feature in VR. For this reason, this paper presents a comparative study of the integration of natural hand interaction in two immersive VR systems: a Cave Audio Visual Experience (CAVE) system –where users’ real hands are visible– and a non-see-through Head-Mounted Display (HMD) system –where only a virtual representation of the hands is possible–. In order to test the suitability of using this type of interaction in a CAVE and compare it to an HMD, we raise six research questions related to task performance, usability and perception differences regarding natural hand interaction with these two systems. To answer these questions, we designed an experiment where users have to complete a pick-and-place task with virtual balls and a text-typing task with virtual keyboards. In both systems, the same tracking technology, based on a Leap Motion device, was used. To the best of our knowledge this is the first academic work addressing a comparison of this type. Objective and subjective data were collected during the experiments. The results show that the HMD has a performance, preference and usability advantage over the CAVE with respect to the integration of natural hand interaction. Nevertheless, the results also show that the CAVE system can be, as well, successfully used in combination with an optical hand tracking device.
Parallel Changes in Positive Youth Development and Self-awareness: the Role of Emotional Self-regulation, Self-esteem, and Self-reflection
Authors: Mertens Esther C. A. , Deković Maja , van Londen Monique , Reitz Ellen
Published: January 2022

The aim of the present study was to examine whether early adolescents’ positive development (i.e., resilience and psychological wellbeing) could be enhanced by stimulating three dimensions of self-awareness: emotional self-regulation, self-esteem, and self-reflection. An experimental field study (randomized controlled trial) was conducted. Seventh grade students (N = 1299; Mage = 12.38; 54% boys) completed multiple assessments at the beginning, during, and immediately after the intervention or at parallel time points for students in the control condition. Changes in the assessed constructs were examined with parallel process latent growth curve models. The results showed that increases in emotional self-regulation and self-esteem were related to concurrent increases in both resilience and psychological wellbeing. Changes in self-reflection were, however, not related to changes in these outcomes. The trajectories of change and parallel processes were similar in the intervention and control condition. These findings suggest that interventions aiming to stimulate positive youth development might be optimized by also focusing on youth’s self-awareness, though more knowledge about how self-awareness can be stimulated best is needed. This trial was registered in the Dutch Trial Register, number NL6371 (old number: NTR6554), on July 3, 2017.
Crustal-scale thermal models: revisiting the influence of deep boundary conditions
Authors: Degen Denise , Veroy Karen , Scheck-Wenderoth Magdalena , Wellmann Florian
Published: January 2022

The societal importance of geothermal energy is significantly increasing because of its low carbon-dioxide footprint. However, geothermal exploration is also subject to high risks. For a better assessment of these risks, extensive parameter studies are required that improve the understanding of the subsurface. This yields computationally demanding analyses. Often, this is compensated by constructing models with a small vertical extent. This paper demonstrates that this leads to entirely boundary-dominated and hence uninformative models. It demonstrates the indispensable requirement to construct models with a large vertical extent to obtain informative models with respect to the model parameters. For this quantitative investigation, global sensitivity studies are essential since they also consider parameter correlations. To compensate for the computationally demanding nature of the analyses, a physics-based machine learning approach is employed, namely the reduced basis method, instead of reducing the physical dimensionality of the model. The reduced basis method yields a significant cost reduction while preserving the physics and a high accuracy, thus providing a more efficient alternative to considering, for instance, a small vertical extent. The reduction of the mathematical instead of physical space leads to less restrictive models and, hence, maintains the model prediction capabilities. The combination of methods is used for a detailed investigation of the influence of model boundary settings in typical regional-scale geothermal simulations and highlights potential problems.
How WEIRD is Cognitive Archaeology? Engaging with the Challenge of Cultural Variation and Sample Diversity
Authors: Killin Anton , Pain Ross
Published: January 2022

In their landmark 2010 paper, “The weirdest people in the world?”, Henrich, Heine, and Norenzayan outlined a serious methodological problem for the psychological and behavioural sciences. Most of the studies produced in the field use people from Western, Educated, Industrialised, Rich and Democratic (WEIRD) societies, yet inferences are often drawn to the species as a whole. In drawing such inferences, researchers implicitly assume that either there is little variation across human populations, or that WEIRD populations are generally representative of the species. Yet neither of these assumptions is justified. In many psychological and behavioural domains, cultural variation begets cognitive variation, and WEIRD samples are recurrently shown to be outliers. In the years since the article was published, attention has focused on the implications this has for research on extant human populations. Here we extend those implications to the study of ancient H. sapiens, their hominin forebears, and cousin lineages. We assess a range of characteristic arguments and key studies in the cognitive archaeology literature, identifying issues stemming from the problem of sample diversity. We then look at how worrying the problem is, and consider some conditions under which inferences to ancient populations via cognitive models might be provisionally justified.
Relationship of iron ore price with other major commodity prices
Authors: Kim Yoochan , Ghosh Apurna , Topal Erkan , Chang Ping
Published: January 2022

Understanding the interdependency of commodity market pricing system is very important for running a successful mining business. Much of the iron ore price is derived from the prices of other commodities. This study investigates the relationship between monthly iron ore prices against 12 other monthly commodity prices or indices including LNG, aluminium, nickel, silver, Australian coal, zinc, gold, oil, tin, copper, lead, and Commodity Price Index (Metals) in both bivariate and multivariate perspectives. An augmented Dickey-Fuller (ADF) test is carried out to ensure that all the time series commodity prices and index are non-stationary. In multivariate modelling co-integration tests, observation is made on how many co-integrations exist out of 12 co-integrations for each respective lag between 0 and 45 months’ period. It is observed that 6 out of 12 commodity prices follow co-integrations in 1-month lag and continues in a cyclic pattern until 27 months after which it disappears. There are 3 commodities which continuously co-integrate with iron ore price change at all lags. For bivariate modelling, vector error correction model (VECM) estimation is carried out to prove the evidence of short-run responses to long-term relationship between iron ore prices and it is observed that oil, copper, and Australian coal prices have influence on and from iron ore prices. Then, Granger causality test is carried out to verify the VECM result by testing bi-directional causality between iron ore prices and copper, oil, and coal prices. It has been concluded that the iron ore price has bi-directional influence on oil, copper, and Australian coal prices and vice versa.
Enhanced electrical property of graphite/Al2O3 composite fabricated by reductive sintering of gel-casted body using cross-linked epoxy polymer
Authors: Funahashi Yoshiaki , Xin Yunzi , Kato Kunihiko , Nguyen Huu Hien , Shirai Takashi
Published: January 2022

In the present study, graphite/alumina composites are fabricated via reductive sintering of gel-casted green bodies with structurally controlled cross-linked epoxy polymers for the first time. The cross-linking degrees of polymers are tuned by the amount ratio of epoxy monomer/polyvinyl alcohol cross-linker utilized in gel-casting process. Superior electrical properties with respect to 5-fold enhanced electrical conductivity and 2-fold higher carrier mobility are successfully achieved in graphite/alumina composite fabricated from cross-linked epoxy polymer, whose phenomenon is attributed to the excellent conductive path in ceramic matrix established by highly uniform network with improved graphitization degree.
Polyimide foam composites with nano-boron nitride (BN) and silicon carbide (SiC) for latent heat storage
Authors: Clausi Marialaura , Zahid Muhammad , Shayganpour Amirreza , Bayer Ilker S.
Published: January 2022

Leaching and instability in wax-based phase change materials (PCMs) are serious application problems. Herein, we developed paper-like (~ 100 µm) flexible, composite PCMs by hydraulic compression of 1-cm-thick polyimide foams between an aluminum foil and a (nano) ceramic composite Parafilm®. An unfilled PCM film placed between the foam and the aluminum surface ensured strong adhesion between the collapsed foam and the metal. Different concentrations of nano-BN and micro-SiC particles were compounded into Parafilm® in order to optimize the thermal performance. Based on infrared imaging, the monoliths containing 30 wt% micro-SiC outperformed all other systems including BN/SiC hybrids. The next best thermal performance was observed with the 60 wt% nano-BN composite. Due to compression, the cellular structure of the polyimide foams collapsed irreversibly while being impregnated by the PCMs from both sides. High-kfillers improved impregnation into the collapsed foam and enabled excellent shape stability and leakage prevention.

Graphical abstract
Neural network guided adjoint computations in dual weighted residual error estimation
Authors: Roth Julian , Schröder Max , Wick Thomas
Published: January 2022

In this work, we are concerned with neural network guided goal-oriented a posteriori error estimation and adaptivity using the dual weighted residual method. The primal problem is solved using classical Galerkin finite elements. The adjoint problem is solved in strong form with a feedforward neural network using two or three hidden layers. The main objective of our approach is to explore alternatives for solving the adjoint problem with greater potential of a numerical cost reduction. The proposed algorithm is based on the general goal-oriented error estimation theorem including both linear and nonlinear stationary partial differential equations and goal functionals. Our developments are substantiated with some numerical experiments that include comparisons of neural network computed adjoints and classical finite element solutions of the adjoints. In the programming software, the open-source library deal.II is successfully coupled with LibTorch, the PyTorch C++ application programming interface.

Article Highlights

Adjoint approximation with feedforward neural network in dual-weighted residual error estimation.

Side-by-side comparisons for accuracy and computational cost with classical finite element computations.

Numerical experiments for linear and nonlinear problems yielding excellent effectivity indices.
On the asymptotic behavior of the Diaconis–Freedman chain in a multi-dimensional simplex
Authors: Peigné Marc , Tran Tat Dat
Published: January 2022

We give a setting of the Diaconis–Freedman chain in a multi-dimensional simplex and consider its asymptotic behavior. By using techniques from random iterated function theory and quasi-compact operator theory, we first give some sufficient conditions which ensure the existence and uniqueness of an invariant probability measure and, in particular cases, explicit formulas for the invariant probability density. Moreover, we completely classify all behaviors of this chain in dimension two. Some other settings of the chain are also discussed.
Gleasonian structure in the helminth metacommunity of the opossumDidelphis albiventrisin two extremes of the Atlantic Forest
Authors: Cirino B.S. , Costa-Neto S.F. , Cardoso T.S. , Estrela P.C. , Maldonado A. , Gentile R.
Published: January 2022

Didelphis albiventrisis the opossum with the largest geographic distribution in Brazil and has a wide spectrum of helminth parasites. This study aimed to describe the species composition and analyse the structure of helminth communities ofD.albiventrisin two extremes of the Atlantic Forest in Brazil. The influence of host sex, body mass, age, helminth species richness and locality on the abundance and prevalence of the most prevalent helminth species was investigated. Ninety-five per cent of the animals were infected with at least one species. Nine helminth species were found: the nematodesAspidodera raillieti,Cruzia tentaculata,Trichuris didelphisandTrichuris minutain the large intestine;Turgida turgidain the stomach;Travassostrongylus orloffiandViannaia hamata; and the trematodesBrachylaima advenaandRhopalias coronatusin the small intestine. Three helminth morphospecies were also recovered: the nematodesHoineffiasp. andViannaiasp. and a cestode in the small intestine.Cruzia tentaculataandV.hamatawere the species with the highest mean abundances and intensities, while the most prevalent species wereA.raillieti,C.tentaculata,T.turgidaandV.hamata, forming the central nucleus of the helminth component community. The analysis of the helminth metacommunity structure indicated a Gleasonian pattern for the total set of infracommunities, corroborating the beta diversity indices, which indicated more species replacement than loss between localities and infracommunities, although at a low level. The results indicated a stronger influence of host attributes than geographical distance on the community structure.
Borderline personality disorder symptom networks across adolescent and adult clinical samples: examining symptom centrality and replicability
Authors: Peters Jessica R. , Crowe Michael L. , Morgan Theresa , Zimmerman Mark , Sharp Carla , Grilo Carlos M. , Sanislow Charles A. , Shea M. Tracie , Zanarini Mary C. , McGlashan Thomas H. , Morey Leslie C. , Skodol Andrew E. , Yen Shirley
Published: January 2022

Background

Numerous theories posit different core features to borderline personality disorder (BPD). Recent advances in network analysis provide a method of examining the relative centrality of BPD symptoms, as well as examine the replicability of findings across samples. Additionally, despite the increase in research supporting the validity of BPD in adolescents, clinicians are reluctant to diagnose BPD in adolescents. Establishing the replicability of the syndrome across adolescents and adults informs clinical practice and research. This study examined the stability of BPD symptom networks and centrality of symptoms across samples varying in age and clinical characteristics.

Methods

Cross-sectional analyses of BPD symptoms from semi-structured diagnostic interviews from the Collaborative Longitudinal Study of Personality Disorders (CLPS), the Methods to Improve Diagnostic Assessment and Service (MIDAS) study, and an adolescent clinical sample. Network attributes, including edge (partial association) strength and node (symptom) expected influence, were compared.

Results

The three networks were largely similar and strongly correlated. Affective instability and identity disturbance emerged as relatively central symptoms across the three samples, and relationship difficulties across adult networks. Differences in network attributes were more evident between networks varying both in age and in BPD symptom severity level.

Conclusions

Findings highlight the relative importance of affective, identity, and relationship symptoms, consistent with several leading theories of BPD. The network structure of BPD symptoms appears generally replicable across multiple large samples including adolescents and adults, providing further support for the validity of the diagnosis across these developmental phases.
Design and development of optically transparent rectenna for RF energy harvesting applications
Authors: Devisowjanya Potti , Gulam Nabi Alsath Mohammed , Kirubaveni Savarimuthu , Sudhilaya G.
Published: January 2022

An optically transparent ultra-wideband (UWB) Vivaldi antenna with a rectifier circuit is proposed in this paper. The proposed antenna is designed and fabricated on a soda-lime glass substrate with fluorine doped conductive oxide (FTO) as the conductive layer. A radial stub is used for better impedance matching and enhancing the impedance bandwidth of the antenna. It operates over a frequency range of 2–6 GHz with a bandwidth of 4 GHz. It has a directional radiation pattern with a realized peak gain of 2.5 dBi at 4 GHz and simulated radiation efficiency greater than 28%. The transparent antenna is integrated with a rectifier and a matching circuit for radio frequency energy harvesting applications. The rectifier and matching circuit is designed on an FR4 substrate. The fabricated rectenna provided a dc voltage of 140 mV from the ambient environment. The proposed rectenna can be installed in handheld devices that increase the scope of applications in automobiles and mobile communications.
Safety, Acceptability, and Initial Effectiveness of a Novel Digital Suicide Prevention Campaign Challenging Perceived Burdensomeness
Authors: Webb Marianne , Carrotte Elise R. , Flego Anna , Vincent Bonnie , Lee-Bates Benjamin , Heath Jack , Blanchard Michelle
Published: January 2022

Abstract. Background: Better Off With You is a peer-to-peer, digital suicide prevention campaign pilot designed to challenge the idea of perceived burdensomeness; the schema experienced by many people contemplating suicide that they are a burden on others. Aims: To investigate the safety, acceptability, and initial effectiveness of the campaign. Method: This mixed methods pilot involved a general community sample ( N = 157), from targeted sites within two Australian communities. Data were collected at baseline and after 1-week exposure to the campaign videos and website. Qualitative interviews were conducted with a subset of participants ( N = 15). Results: Participants rated the campaign as highly engaging and relevant to local communities. In interviews, participants identified the campaign as being unique, safe, and impactful. Overall, exposure to Better Off With You did not result in any notable changes in perceived burdensomeness, psychological distress, or help-seeking. Limitations: The pilot involved a community sample. As such, outcome measurement scores were low at baseline. Conclusion: This pilot provides new insights about the safety, engagement and initial effectiveness of the Better Off With You campaign. Future research is needed to explore its impact on people experiencing suicidal ideation.
Depressive Symptoms Moderate the Association Between the Recent History of Alcohol Use Severity and Suicide Attempt History Among Adults in a Pretrial Jail Diversion Program
Authors: Mitchell Sean M. , Görgülü Tuğba , Dhingra Katie , Crean Hugh F. , Swogger Marc T.
Published: January 2022

Abstract: Background: Justice-involved individuals are at elevated risk for suicidal behavior; however, research examining risk for suicidal behavior in pretrial jail diversion programs (pretrial diversion) is limited. Aims: We aimed to test (1) associations between depressive symptoms and alcohol and drug use, and suicide attempt history (SAH), and (2) interactions between depressive symptoms and alcohol and drug use in relation to SAH among adults in an urban pretrial jail diversion program. Method: The design was cross-sectional, including self-report assessments and file reviews of historical information. Adults ( N = 274; M age = 33.72; 73.7% men; 52.6% non-Hispanic Black) completed assessments within two weeks of beginning the pretrial program. Results: Depressive symptoms were positively associated with SAH after adjusting for other covariates. The significant depressive symptoms by alcohol use interaction indicated that adults with low to average depressive symptoms evidenced a similar likelihood of SAH to those with high depressive symptoms when they also had elevated alcohol use scores. Limitations: We used cross-sectional self-report data. Conclusion: It may be important to conduct suicide risk assessments for justice-involved people who use alcohol even when depressive symptoms are low.
Interpretation of Subsurface Salinity EOFs on Southern ECS Shelf Using SODA Reanalysis: Large‐Scale Patterns and Seasonal to Interannual Variations
Authors: Qi Peng , Guo Yun‐xia
Published: January 2022

In the southern East China Sea (ECS), low‐salinity shelf water is distinguished from high‐salinity Kuroshio water. Neutral density solution of subsurface salinity in southern ECS with Empirical Orthogonal Function (EOF) analysis of Simple Ocean Data Assimilation (SODA) reanalysis data (1958‐2008) is presented. This study focuses on seasonal to interannual variations of large‐scale patterns. We choose isopycnal 24.5 as the representative of subsurface layers, which is the deepest of the Kuroshio subsurface that can outcrop to sea surface during winter and early spring. We conducted EOF both including and excluding the seasonal signal. The results show that annual cycles dominate the first two leading EOF modes, EOF‐1 representing inner‐shelf oscillation, and EOF‐2 outer‐shelf oscillation. However, EOF‐2 also shows significant interannual variability. To this end, we removed the seasonal signal from the dataset and recalculated EOF. We found that the interannual EOF‐1 is of cross‐shelf in spatial pattern and shows significant interannual variability. This suggests that seaward penetration of the shelf water and shelfward intrusion of the Kuroshio that mainly occur in winter and early spring are a pair of contradictions in the two‐way intrusions, which are modulated by significant interannual variability. We also found that the isopycnal extending abnormally northward and outcropping in early spring corresponds to significant non‐intrusions of the Kuroshio. In the underlying dynamics, oceanic stratification, besides topography uplifting, plays an important role in the subsurface intrusion of Kuroshio off northeast Taiwan.
Long‐Range Lateral Transport of Dissolved Manganese and Iron in the Subarctic Pacific
Authors: Wong Kuo Hong , Nishioka Jun , Kim Taejin , Obata Hajime
Published: January 2022

Dissolved manganese (dMn) and iron (dFe) are important micronutrients for marine microorganisms. In this study, we presented comprehensive distributions of dMn in the subarctic Pacific and compared our Mn data with those of dFe in the same region. dMn and dFe exhibited a scavenged‐type and nutrient‐type vertical profile, respectively. We also determined the size fractionation of Mn at two stations and found that most of dMn was in the soluble fraction, in contrast to dFe, which included colloidal organic particles. In the coastal surface waters of the Gulf of Alaska, Mn was supplied from a riverine source. Drawdowns of dFe, dMn, and macronutrient were observed along the salinity gradient. Both dMn and dFe were transported eastward, with log‐scale transport distances of 3,600 and 3,300 km, respectively in the upper intermediate water, and 4,700 and 3,400 km, respectively in the lower intermediate water. In the upper intermediate water, dMn showed a positive relationship with apparent oxygen utilization, suggesting that regeneration processes could supply dMn to these waters. However, mixing with water masses from the subtropical North Pacific reduced dMn concentration. High dissolved oxygen concentrations in these waters also increased the rate of dMn loss relative to the lower intermediate water. The transport distances of dMn found in this study were the highest in the Pacific region. This long‐range transport of dMn and dFe could eventually fuel phytoplankton growth at the surface via upwelling processes.
Non‐Local Energy Dissipation of Lee Waves and Turbulence in the South China Sea
Authors: Zheng Kaiwen , Nikurashin Maxim , Tian Jiwei
Published: January 2022

Breaking of internal lee waves has been shown to drive enhanced turbulence and mixing in regions where strong bottom flows interact with rough topography. However, theoretical predictions for the energy conversion from the bottom flows into lee waves differ from the corresponding turbulent energy dissipation rates observed locally at the wave generation sites. Recent idealized numerical simulations suggest that the discrepancy may be attributed to non‐local wave breaking and dissipation effects: when a mean flow impinges on rough topography and generates lee waves and turbulence, a significant fraction of the generated energy gets advected downstream of the generation site and dissipates remotely. Here, we present a case study for the non‐local lee wave energy dissipation in the South China Sea by using a combination of in situ mooring observations of the bottom flow interacting with two topographic features and corresponding numerical simulations. The results show that most of the near‐inertial and high‐frequency response observed at the mooring site is not locally generated, but rather is produced by the interaction of the subinertial flow with the topographic feature upstream. The wave and turbulent energy detected at the mooring site can be enhanced by an order of magnitude compared to the energy of the locally generated motions. The simulations confirm that up to 70% of the enhanced energy is advected into the region by the subinertial flow, while the rest is radiated into the region as waves. Implication of our results for mixing observations and ocean model parameterizations are discussed.
On the Correspondence Between Atmosphere‐Only and Coupled Simulations for Radiative Feedbacks and Forcing From CO2
Authors: Qin Yi , Zelinka Mark D. , Klein Stephen A.
Published: January 2022

Atmosphere‐only experiments are widely used to investigate climate feedbacks simulated in more computationally expensive fully coupled global climate model simulations. We confirm that this remains a valid approach by comparing the radiative feedbacks and forcing between coupled and atmosphere‐only simulations for the latest models taking part in the 6th phase of the Coupled Model Intercomparison Project (CMIP6). For global‐mean cloud feedbacks, we find a better than previously known correspondence between these experiments, which applies even to the response of individual cloud properties (amount, altitude, and optical depth) and holds even when considering atmosphere‐only simulations of only 1 yr duration. For regional cloud feedbacks, the correspondence between the two experiments is generally present at every geographic location except for the tropical Pacific but takes longer experiments to reveal. For the lapse rate and surface albedo feedbacks, the correspondence between the two experiments is weaker due to the non‐uniform warming pattern and loss of sea ice in the coupled experiment. For the across‐model relationship between 4xCO2 effective radiative forcing and feedback, we find a different behavior across experiments in CMIP6 than in CMIP5, casting doubt on the physical significance of previous results that highlighted an anti‐correlation between the two quantities. Overall, these results confirm the utility of atmosphere‐only experiments particularly to study cloud feedbacks, which are the dominant source of inter‐model spread in climate sensitivity.
Aquatic Insect Bioconstructions Modify Fine‐Sediment Entrainment and Mobility
Authors: Mason R. J. , Rice S. P. , Johnson M. F. , Wood P. J. , Vettori D.
Published: January 2022

The importance of two‐way interactions between animals and the physical hydraulic and sedimentological environment are increasingly recognized (e.g., zoogeomorphology). Caddisflies (Trichoptera) are a group of aquatic insects known for their bioconstructions, particularly cases built from fine sediment and silk. Caddisfly cases differ in size, shape and density from the incorporated sediment, and case construction may therefore affect the mobility of these sediments in rivers. However, although communities of caddisfly often use substantial quantities of sediment in case construction, the effect of these bioconstructions on sediment transport in rivers is unknown. We use a flume experiment to compare the bed shear stress required to transport (a) empty caddisfly cases and (b) individual sediment particles, following disaggregation from the case. The cases of three species were considered; two that construct different styles of tubular case (Potamophlax latipennis and Sericostoma personatum) and one that builds a domed case (Agapetus fuscipes). P. latipennis and S. personatum cases were easier to entrain than the sediment grains incorporated into them, whilst A. fuscipes cases were not. Despite their low mass, A. fuscipes cases required the most shear stress to transport them because their domed shape impeded rolling. These findings are important to understand how differences in case design between species, reflect different adaptation strategies to the turbulent hydraulic river habitat. Furthermore, the results suggest that un‐attached tubular caddisfly cases may be preferentially transported over other particles on the river bed and thus, where caddisfly occur in high abundance, they may increase fluvial entrainment of sand.
Genomic characterization of functional high-risk multiple myeloma patients
Authors: Soekojo Cinnie Yentia , Chung Tae-Hoon , Furqan Muhammad Shaheryar , Chng Wee Joo
Published: January 2022

Multiple myeloma (MM) patients with suboptimal response to induction therapy or early relapse, classified as the functional high-risk (FHR) patients, have been shown to have poor outcomes. We evaluated newly-diagnosed MM patients in the CoMMpass dataset and divided them into three groups: genomic high-risk (GHR) group for patients with t(4;14) or t(14;16) or complete loss of functional TP53 (bi-allelic deletion of TP53 or mono-allelic deletion of 17p13 (del17p13) and TP53 mutation) or 1q21 gain and International Staging System (ISS) stage 3; FHR group for patients who had no markers of GHR group but were refractory to induction therapy or had early relapse within 12 months; and standard-risk (SR) group for patients who did not fulfill any of the criteria for GHR or FHR. FHR patients had the worst survival. FHR patients are characterized by increased mutations affecting the IL-6/JAK/STAT3 pathway, and a gene expression profile associated with aberrant mitosis and DNA damage response. This is also corroborated by the association with the mutational signature associated with abnormal DNA damage response. We have also developed a machine learning based classifier that can identify most of these patients at diagnosis.
An investigation into the management of the deep carious lesion by general dental practitioners in the UK
Authors: Patel Sheena , Fine Peter , Shukla Mandeep , Blizard Robert , Leung Albert
Published: January 2022

Objectives As techniques and dental materials have evolved, the management of deep carious lesions has also changed. This study investigated how UK-based general dental practitioners (GDPs) managed deep carious lesions in permanent, vital teeth and factors that influence their choices.

Methods This mixed-method study employed an online questionnaire as its primary source of quantitative data collection. The questionnaire enquired about GDPs': a) demographics; b) working environment; and c) whether they had postgraduate training that covered caries management/minimally invasive dentistry (MID). Respondents were presented with a clinical case to elicit qualitative data. Relevant questions were asked in order to examine current practice and explore treatment among the respondents.

Results In total, 239 responses were received. Overall, 168 (70% [95% CI 64%, 76%]) of the respondents chose a partial caries removal technique, 155 (69.3% [95% CI 60%, 72%]) used an adhesive restorative material and 205 (85.8% [95% CI 81%, 89%]) advised fluoride adjuncts. However, rubber dam (75; 31.4% [95% CI 26%, 38%]) and saliva testing (17; 7.1% [95% CI 4%, 11%]) were not routinely used. A significant relationship between those who had postgraduate training and those who chose partial caries removal as their treatment choice (χ2 = 6.27; p = 0.01) was noted. Respondents working in an NHS-based practice were significantly (χ2 = 34.98; p <0.001) more likely to restore teeth with amalgam.

Conclusions There is an inconsistent management protocol when presented with a deep carious lesion, but partial caries removal is more widely adopted than previously reported. Rubber dam isolation was not routinely used when choosing to restore a deep carious lesion. Those who have had postgraduate training felt more confident in offering MID, so there is a clear need for further education to ensure its engagement.
Inequitable patterns of US flood risk in the Anthropocene
Authors: Wing Oliver E. J. , Lehman William , Bates Paul D. , Sampson Christopher C. , Quinn Niall , Smith Andrew M. , Neal Jeffrey C. , Porter Jeremy R. , Kousky Carolyn
Published: January 2022

Current flood risk mapping, relying on historical observations, fails to account for increasing threat under climate change. Incorporating recent developments in inundation modelling, here we show a 26.4% (24.1–29.1%) increase in US flood risk by 2050 due to climate change alone under RCP4.5. Our national depiction of comprehensive and high-resolution flood risk estimates in the United States indicates current average annual losses of US$32.1 billion (US$30.5–33.8 billion) in 2020’s climate, which are borne disproportionately by poorer communities with a proportionally larger White population. The future increase in risk will disproportionately impact Black communities, while remaining concentrated on the Atlantic and Gulf coasts. Furthermore, projected population change (SSP2) could cause flood risk increases that outweigh the impact of climate change fourfold. These results make clear the need for adaptation to flood and emergent climate risks in the United States, with mitigation required to prevent the acceleration of these risks.