bluuebunny/crossref_metadata_2025 huggingface dataset:
Health and Safety Issues in Selected Nigerian Medium-Sized Manufacturing Firms
Authors: Akinbode James , Ebeloku Ademola , Unuafe Francisca , Akintunde-Adeyi Julianah
Published: December 2024

Introduction: Medium-sized firms around the world are confronted with several challenges which have continued to hamper their growth chances. One of these issues is lack of global best practices in health and safety. This issue is pronounced among medium-sized manufacturing firms in Nigeria. It was against this backdrop that the study investigated the state of health and safety issues in selected Nigerian medium-sized manufacturing firms. Methods: Survey research design was adopted involving leading medium-sized manufacturing firms in Nigeria. Issues pertaining to health and safety were identified and analyzed. Data were gathered through administration of structured questionnaire and observation check list. Analyses were presented through appropriate statistical means. Results: Relatively secured work environment, workers’ exposure to hazard, absence and inadequate protective devices for workers, archaic fire system infrastructure, lack of insurance cover for workers, irregular health and safety training, inconsistent compliance to health and safety rules were found as the issues in selected Nigerian medium-sized manufacturing firms operating in Nigeria. Conclusion: Health and safety issues is a cog in the wheel of Nigerian medium-sized manufacturing firms. It is imperative to address this issue to strengthen the operations of the industry. The promotion and practice of hygienic health system and safety culture by workers and management must be the way of life in manufacturing firms.
RECOMMENDATIONS TO IMPROVE EMPLOYEE PERSONAL ATTITUDE TOWARD REPORTING PATIENT SAFETY INCIDENTS
Authors: Andari Purwo , Handriyanto Candra Ferdian , Damayanti Nyoman Anita , Pudjirahardjo Widodo Jatim
Published: December 2024

Background: Patient Safety Incidents (PSI) in hospitals are adverse events that need to be reported for effective identification and risk management, aiming to prevent reoccurrence of incidents. However, not all incidents are documented, as evidenced by the discrepancy in the number of phlebitis reported by employees as well as Infection IPCLN at three hospitals.
Aims: Provide recommendations to improve employee Personal Attitude towards reporting PSI at three hospitals owned by Company A.
Methods: The method adopted was a cross-sectional research design; data were collected from three hospitals owned by company A and tested using multiple logistic regression statistics tests. Data on Phlebitis reported from January to July 2018 at three hospitals owned by Company A was used. Furthermore,135 respondents were taken from the service installations of the three hospitals. The Lameshow formula and proportional random sampling are applied to determine the sample.
Results: The variables of error orientation (p = 0.001; β = 0.349), behavioral belief (p = 0.008; β = 0.234), and perceived behavioral control (p = 0.003; β = 0.222) had a positive and significant effect on the personal attitude of employees reporting PSI.
Conclusion: Two approaches were recommended to improve the personal attitude of employees in reporting PSI.
Keywords: Hospital, Patient safety incidents, Personal attitude, Underreporting
THE COST OF SMS REMINDER TO IMPROVE ARV ADHERENCE AMONG KEY POPULATIONS
Authors: Juwita Mery Nurma , Donny Hardiawan  , Prawinegara Rozar , Handayani Miasari , Wisaksana Rudi , Januraga Pande Putu , Sulaiman Nurjannah , Siregar Adiatma
Published: December 2024

Background: HATI is an implementation trial aimed at improving HIV care and treatment, including through SMS reminders.
Aims: This study aimed to estimate the cost and analyze the outcomes of providing SMS Reminders within the HATI program in different settings.
Methods: Data were analyzed using a micro-costing approach from providers' and health systems' perspectives. Subjects were divided into intervention and control groups for outcome analysis, with adherence as the outcome indicator.
Results: From a provider's perspective, the highest cost was incurred in primary health care (PHC) clinics, while the lowest was in hospital clinics, most likely due to a much higher volume of SMS sent from hospitals. Costs from the health system perspective were more than two times higher than those from the provider perspective, as they included costs borne by HATI management and intervention setup. In one year, the number of patients with >95% adherent visits was higher in the intervention group than the control group, although visits decreased over time in both groups. The highest number of patients with >95% adherent visits was found in PHC clinics, while the lowest was in hospital clinics.
Conclusion: SMS reminders can be expensive initially due to setup and program costs. However, they become cheaper once they are embedded into the existing system. Further studies are necessary to determine better site options for scaling up SMS reminder intervention and to study the declining adherence rate in all clinics.
Keywords: Adherence, cost analysis, HIV, Indonesia, SMS reminder
ENDÜSTRİYEL TASARIMDA SÜRDÜRÜLEBİLİRLİK GİRDİSİNİN MOBİLYA ENDÜSTRİSİ ÜZERİNDEN DEĞERLENDİRİLMESİ
Authors: Ekmekçioğlu Deniz
Published: December 2024

Sürdürülebilirlik kavramı, sorumsuz tüketim ile öne çıkan ekolojik sorumluluk ve uzun vadede doğal kaynakların yönetilme ihtiyacının giderek artması gibi birçok alanı kapsayan kritik bir durum olarak ortaya çıkmıştır. Sürdürülebilirlik için tasarım ise bu eko sistem çerçevesinde hem tasarım literatüründe ve hem de tasarım eğitiminde önemli bir pozisyonda konumlanmaktadır. Sürdürülebilirlik ve sürdürülebilirlik için tasarım kavramları birçok sektörlerde olduğu gibi mobilya endüstrisinin de gündeminde bulunmaktadır. Mobilya günümüzde hızlı tüketim ürünlerinden biri olmakla birlikte, tüketim davranışlarından dolayı çevresel sorunlara da yol açmaktadır. Fakat sürdürülebilir tasarım uygulamalarının önemi birçok akademik yayında vurgulanmasına rağmen sınırlı olarak uygulanması ve endüstride bu yaklaşımın karşılığının sınırlı olması bir problem olarak tanımlanmaktadır. Bu çerçevede araştırmada, Doğanlar Mobilya Grubu Tasarım Merkezi örneği ele alınarak, mobilya sektöründe sürdürülebilirlik yaklaşımlarının endüstriyel tasarım literatürü altında değerlendirilmesi amaçlanmıştır. Çalışma, mobilya sektöründe en az beş yıllık deneyime sahip endüstriyel tasarımcılardan oluşan odak grup çalışması ile gerçekleştirilmiştir. Nitel bir yaklaşımla ele alınan araştırmada, odak grup tartışması tematik ve tümevarım bir yaklaşım kullanılarak analiz edilmiş ve veriler sistematik olarak SWOT kategorilerine göre sınıflandırılmıştır. Ayrıca, çalışmanın tasarımda sürdürülebilirlik ilkelerine yaptığı vurgu, mobilya endüstrisinde sürdürülebilir tasarım uygulamalarının sınırlı bir şekilde uygulanmasına yönelik küresel eleştirilerle de uyumlu olarak ele alınmıştır.
ÇAĞDAŞ HEYKEL SANATINDA TEMSİL STRATEJİSİ OLARAK KÜÇÜK ÖLÇEKLİ İNSAN FİGÜRLERİ
Authors: Barlas Mert
Published: December 2024

Araştırmada çağdaş heykel sanatında yer alan figür pratiklerinde küçük ölçeğin bir temsiliyet tercihi ve bağlam unsuru olarak ele alınması durumu; çağdaş sanat kapsamında değişen ölçek algısı doğrultusunda ölçekte indirgemenin/ ölçek manipülasyonun ne ifade ettiği çözümlenerek ele alınmaktadır. Araştırma, figüratif heykelde küçük ölçek tercihinin sanatçıların ele aldığı eser temalarına olan etkilerini, çağdaş heykel sanatı içerisinde öne çıkan; Isaac Cordal, Ron Mueck, Tomoaki Suzuki ve Stephan Balkenhol gibi sanatçıların eserleri ışığında sorgulamaya açmaktadır. Araştırmaya konu olan kavramların ve eserlerin çözümlemelerine yönelik; kuramsal içeriği oluşturmak amacıyla literatür taranmıştır. Ulaşılan verilerden araştırmacının konuyla ilgili düşüncelerini destekleyen kaynaklar seçilmiştir. Kaynaklardan elde edilen veriler, salt alıntı şeklinde bırakılmamış, araştırmaya bağlı olarak konu ile ilgili tespitlerde bulunulmuş, alıntılar sorgulanarak yorumlanmış/ çözümlenmiştir. Bu anlamda araştırma genelinde, değerlendirmeye alınan sanatçıların eserleri üzerinden çözümlemelerinde yardımıyla; figür pratiklerinde indirgenmiş ölçeğin varoluşsal ve toplumsal yeni bağlamları keşfetmek ve izleyiciye iletmek amacıyla sıklıkla değişime sokulan bir nitelik olduğu, bedenin/insan formunun görsel ve kavramsal yönlerini varoluşsal çerçeveler içinde aktarmak için temel çıkış noktalarından biri olmak adına önemli roller üstlendiği, izleyiciyi mevcut fiziksel zaman ve mekân algısından koparma potansiyeli taşıdığı, kişisel yaşam örüntülerine, psikolojiye dönük olarak izleyiciyi etkilediği dolayısıyla iç gözlemsel tefekküre teşvik ettiği, sonuç olarak heykelsi hikâye anlatımının sınırlarını da yeniden tanımladığı bulgular dahilinde söylenebilir.
FACTORS INFLUENCING INDIVIDUAL CONSUMERS’ INTENTIONS TO PURCHASE ELECTRIC VEHICLES IN URBAN HANOI
Authors: THAI Nguyen Hong , QUAN Thach Minh
Published: December 2024

This study aims to identify the factors influencing the intention to purchase electric vehicles for personal use among residents in major urban areas in Vietnam, specifically in Hanoi. This research was conducted using a non-probability sampling method to recruit 360 participants currently residing, studying, or working in the city of Hanoi. Statistical analysis was employed to process the collected data. The results reveal four groups of factors that have an impact on the intention to purchase electric vehicles among urban residents in Hanoi: (1) attitude (economic benefits, environment, safety, convenience, and design), (2) perceived behavioral control, (3) attractiveness of alternative modes of transportation, and (4) subjective norms. Based on the findings, the authors propose several policy implications to promote the development and use of electric vehicles in urban Hanoi. These may include encouraging the use of electric vehicles from economic, environmental, and safety perspectives, creating financial support programs or tax incentives for electric vehicle buyers, and improving public electric charging infrastructure to make electric vehicle usage more convenient.
OPERATING PECULIARITIES OF STANDARD COOLING SYSTEMS OF ENGINES AT HIGH ALTITUDES
Authors: MYRZAKHMETOV Beibit , SŁADKOWSKI Aleksander , MASHATAYEVA Gulzada
Published: December 2024

The item under test was the engine without its standard facility-based cooling systems, the lack of which makes it impossible to operate as a power unit of a vehicle in a great majority of experimental research of internal combustion engines at high altitudes. The findings may create a wrong impression of the range of power ratings and economic parameters of the engine when operating at high altitudes because changes in atmospheric conditions exert an effect on the running efficiency of its standard systems as well. It is established that the efficiency loss of the cooling system may cause a forced power limitation of the engine as a result of the experimental research of the diesel engine equipped with all standard facility-based systems at very high altitudes. Thus, the shortage of power may significantly exceed the power loss of the engine due to air density reduction at high altitudes.
PREDICTION OF THE MAIN ENVIRONMENTAL AND ENERGY CHARACTERISTICS OF DIESEL ENGINES USING AN ARTIFICIAL NEURAL NETWORK FOR PURE DIESEL FUEL, PURE HVO, AND A MIXTURE OF THESE FUELS IN THE RATIO 50/50 BY VOLUME
Authors: MATIJOŠIUS Jonas , RIMKUS Alfredas , GRUODIS Alytis
Published: December 2024

This research assesses the influence of different quantities of hydrotreated vegetable oil (HVO) in diesel fuel on the performance of the engine and the emissions it produces. The particular areas of interest are the level of smoke emitted and the brake thermal efficiency (BTE). A series of engine experiments were undertaken to quantify emissions and performance characteristics under various operating regimes using three distinct fuel blends: D100 (pure diesel), HVO50 (50% HVO mixture), and HVO100 (pure HVO). The results show a tendency to reduce soot emissions when the amount of HVO in the mixture reaches 50%, but in order to accurately determine the correlation between the amount of HVO and emissions, additional studies with various concentrations of HVO and diesel mixtures are necessary. Similarly, the results show a slight improvement in BTE stability with a 50% HVO blend, but more studies with different percentages of HVO diesel blends are needed to reliably determine changes in BTE. This indicates a trend of change in engine performance with increasing HVO concentration in diesel fuel. In order to forecast emissions and performance indicators under different operating scenarios, we used artificial neural networks ANNs, which demonstrated excellent prediction accuracy, exhibiting robust linear correlations between the expected and real values for all fuel types. This research emphasizes the advantages of utilizing HVO in diesel engines for both environmental impact and performance. It also emphasizes the usefulness of ANNs in optimizing engine settings to improve efficiency and minimize emissions. The results endorse the further use of HVO as a viable substitute for conventional diesel, leading to less ecological consequences and enhanced engine efficiency.
INDUSTRIAL SNOW AND SELECTED ECONOMIC IMPACTS ON THE OPERATION OF KOSICE AIRPORT
Authors: CHOMA Ladislav , CECHOVA Maria , SUTAK Lubomir , ARVAY Frederik
Published: December 2024

The aim of the paper is to describe industrial snow as a meteorological phenomenon of anthropological origin and the physical principle of its formation in the context of Kosice Airport, with international traffic. The research also focused on selected economic impacts on the operation of Kosice Airport, which is located next to the large industrial complex U.S. Steel Kosice. There are only a few international airports in the world that are affected by industrial snow, which is why we also focus on the economic impact of maintaining the operational areas of the airport to the required extent according to standards. A solution to the problem is also proposed based on the scientific works of experts who focused their scientific activities on the issue of industrial snow production. In addition to the differences in the formation of industrial and natural snow, the article mentions the differences in the structure and properties of crystalline elements and their distribution according to the external meteorological conditions under which they are formed. The paper identifies meteorological situations that are favorable for the formation of industrial snow and due to the mutual location of the airport and the industrial complex, the airport is affected by industrial snow. This article describes the selected economic impacts of industrial snowfall on air traffic at Kosice Airport from 2017–2022. These were expressed after providing data from the airfield maintenance department of the Kosice Airport. At the same time, airport maintenance workers shared their unique experiences with this special meteorological phenomenon. The outcome of this research brings the unique method of industrial snow day occurrence and helps to explain this rare weather phenomenon and its impact on transport and social aspects.
SYNCHRONIZATION OF THE LAST-TRAIN TIMETABLE CONSIDERING PASSENGER TRANSFER TIME
Authors: YÜKSEL Taha , ÖZTÜRK Zübeyde
Published: December 2024

Unsynchronized integrated lines in urban rail systems may cause some passengers to miss their last transfer chance. Therefore, passengers move faster in a swarm mentality to catch the last train. This study aims to synchronize the last-train timetable so that the maximum possible number of passengers can be transferred at the transfer stations by waiting for the minimum time. This paper provides a new approach to show that passengers who try to get to the last train at the transfer station move faster and describes the transfer processes with heuristic algorithms. In the case of the Istanbul urban rail system, passengers transfer to the last train 32% faster than average. To find the heuristic algorithm that defines the transfer processes of these passengers, particle swarm algorithms, dragonfly algorithms, and a simulated annealing algorithm were selected for comparison. The transfer times obtained with the particle swarm algorithm and the actual transfer times gave close results between 97.6% and 99.2%. The modified last-train timetable with predicted transfer time increases the number of successful transfers by 28%, decreasing the average waiting time of passengers from 197.27 seconds to 50.56 seconds. In addition, passengers wait 58 seconds less for the transfer to the last train by adjusting the timetable to the modified last train transfer time.
Enhancing mental health service use: insights from caregivers, providers, and managers in Ghana
Authors: Daliri Dennis Bomansang , Aninanya Gifty Apiung , Agani Afaya , Laari Timothy Tienbia , Abagye Nancy
Published: December 2024

Globally, there is a significant challenge in the acceptability and utilization of mental health services. This issue is particularly pronounced in low- and middle-income countries (LMICs). This study, grounded in the socioecological model, explores the recommendations and perspectives of family caregivers and service providers on improving mental health service utilization in the Bolgatanga Municipality of the Upper East Region of Ghana. A descriptive qualitative research design was employed to explore the views of 15 family caregivers, two service providers, and two mental health service managers on strategies to improve mental health service utilization. From February to March 2023, individual in-depth interviews were conducted, with data collection and analysis occurring concurrently. Participants recommended interventions at multiple levels. At the community level, they suggested increasing mental health awareness. At the organizational level, they emphasized the need to improve staff attitudes, address staffing shortages, and resolve transportation challenges. At the policy level, key suggestions included incorporating mental health services into the National Health Insurance Scheme (NHIS) and increasing access to specialist mental health services. The study provides actionable recommendations to improve mental health service utilization. These include enhancing community awareness about mental health, increasing staffing levels, addressing negative attitudes among health professionals, ensuring the availability of specialist mental health services, and integrating mental healthcare into the NHIS. Implementing these recommendations could significantly enhance the uptake of mental health services in Ghana.
Separable Optimal Weights for Bidirectional Ray Tracing with Photon Maps while Mixing 3 Strategies
Authors: Ershov Sergey Valentinovich , Kopylov Mikhail Sergeevich , Voloboy Alexey Gennadievich
Published: December 2024

Noise in the resultant image is inherent in the widely used bidirectional stochastic ray tracing with photon maps. The noise can be reduced by the Multiple Importance Sampling which combines results of different strategies with weights. In this paper we investigate the separable weights, derive and solve the system of integral equations that determine the optimal weights. It has several qualitative differences from the previously investigated case of general weights and results in more simple and numerically robust expressions. As before, they can be solved in the form of an algebraic formula that includes several integrals of the known functions that can be calculated in ray tracing. The integral terms entering those expressions are of primary importance and do not admit any simple heuristics but must be calculated accurately.
Sikap Petani Padi terhadap Penggunaan Combine Harvester di Kecamatan Paron Kabupaten Ngawi
Authors: Mardiana Sindy Icha , Widiyanti Emi , Rusdiyana Eksa
Published: December 2024

The increasingly advanced development of agricultural technology in Indonesia leads to agricultural modernization. The technology currently developing in Indonesia, especially in terms of harvesting rice plants, is the combine harvester. Many farmers already use combines, one of which is the people of Jambangan and Ngale Villages, Paron Sub-district, Ngawi Regency. Using a combine harvester can provide benefits for farmers, especially in terms of efficiency in harvesting rice crops. This research aims to 1) find out the impact of using the combine harvester machine; 2) analyze the attitudes of rice farmers towards using the combine harvester machine; 3) analyze the factors that influence the attitudes of rice farmers towards using the combine harvester in Paron Sub-district, Ngawi Regency. The research method uses a quantitative approach with survey techniques. The sample consisted of 43 people and was determined using proportional random sampling. Data analysis uses multiple linear regression analysis. The results of the research show 1) the positive impact of using combine harvester technology in increasing harvest efficiency while the negative impact is resulting in soil density and a reduction in labor labor for harvesting up to 92%; 2) the attitude of rice farmers towards the use of combine harvesters is in the strongly agree category with a percentage of 80.12%; 3) the results of the analysis of factors that influence the attitudes of rice farmers towards the use of combine harvesters in Paron Sub-district, Ngawi Regency show that non-formal education and experience have a significant influence.
Peran Penyuluh Pertanian dalam Pembuatan Pupuk Organik melalui Budidaya Maggot di Desa Sukamakmur Kecamatan Ajung Kabupaten Jember
Authors: Candra Mohammad Wiki , Sofia Sofia , Puspaningrum Diah , Luthfiyah Lenny
Published: December 2024

This research aims to determine the role of agricultural extensionist in making organic fertilizer through maggot cultivation in Sukamakmur Village, Ajung Sub-district, Jember Regency. This research uses qualitative descriptive approach. Data collection uses observation, in-depth interviews, and documentation. Data analysis uses Miles and Huberman model. The research results show that role of agricultural extensionist in making organic fertilizer through maggot cultivation is divided into three processes, namely planning, management and results of maggot cultivation. In planning, extension workers carry out role of analysts in identifying environment through site surveys, checking tools, materials and feed. Extension agents as facilitators help provide tools and materials, capital and look for market opportunities. Extension agents as organizers carry out coordination, communication and evaluation. As an extension dynamist, mobilizes members of Tirto Bakti II farmer group to actively participate in comparative studies and bazaars. The role of motivator is carried out by motivating in verbal communication and plot demonstration. Extensionist as initiator provides suggestions in making derivative products such as fish feed, creating new packaging and labels. In management, extensionist as teachers/mentors carry out socialization and training activities. As a liaison, extensionist helping in preparing proposals of request assistance and facilities to the government. As advisors, extensionist advise on maintaining sustainability of maggot cultivation so that it continues to operate and increases the targets to be achieved. In the results of maggot cultivation, as agents of change, extensionist influence communities’ mindset to utilize waste through maggot cultivation and meet fertilizer needs with organic fertilizers.
Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair
Authors: Cong Ting , Morse Kyle W. , Sosa Branden R. , Lane Joseph M. , Rodeo Scott A. , Greenblatt Matthew B.
Published: December 2024

➢ Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.

➢ SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.

➢ SSCs express specific combinations of cell surface markers that reflect their lineage identity.

➢ SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.
Evaluación del potencial forrajero y composición nutricional del pasto híbrido Cuba OM-22 (Pennisetum purpureum Schumach x Pennisetum glaucum L.) a tres edades de corte
Authors: Morocho G.A. , Toalombo P.A. , Guevara H.P. , Jiménez S.F.
Published: December 2024

En el Cantón Joya de los Sacha, Orellana, Ecuador, se evaluó el potencial forrajero y composición nutricional del Pennisetum purpureum Schumach x Pennisetum glaucum L.(Cuba OM-22) en diferentes edades de corte. Los factores de estudio fueron los intervalos de defoliación:30, 45 y 60 días. Se utilizó 16 repeticiones por tratamiento las cuales fueron sujetas a un Diseño de Bloques Completamente al Azar; las variables se sometieron a un ADEVA, las medias a la prueba de Tukey al 95%, además se efectuó un análisis de regresión y correlación. En la valoración agronómica se aplicó las técnicas descritas por Toledo (1982) y Canfield (1941), AOAC (2012) para el análisis proximal y paredes celulares; la digestibilidad in vitro (DIV) se basó en la metodología de Van Soest (1994). Las variables agronómicas presentaron diferencias estadísticas altamente significativas; registrándose los mayores valores a los 60 días excepto en la cobertura aérea, obteniendo a esta edad una altura de 2,42 metros, 68,56 tallos/planta, 49,35% cobertura basal, 102,46 t/ha forraje verde y 12,43 t/ha forraje seco, existiendo una alta regresión y correlación entre las variables agronómicas y la edad de corte. En el análisis bromatológico y paredes celulares, los mejores resultados se alcanzaron a los 30 días; se presentaron diferencias estadísticas altamente significativas en la proteína (14,20%), FDA (34,67%) y FDN (56,29%), mientras que en la fracción ceniza (19,04%) y grasa (2,84%) se registró diferencias significativas. En la DIV se reportó diferencias altamente significativas, siendo los 30 días de defoliación el que posee mayor digestibilidad de la materia seca (71,20%) y orgánica (74,31%). Con esto se afirma que al transcurrir el período de corte, las variables nutricionales sufren un descenso en su contenido. La mejor edad de corte está a los 60 días, debido a que existe un equilibrio entre la parte productiva y nutricional.
Análisis Detallado de las Interconexiones entre los Registros Genealógicos de las Razas Caninas en las Islas Baleares
Authors: Alanzor Puente J.M. , Pons Barro Á.L. , González Ariza A. , Marín Navas C. , Concepción Felipe I. , Delgado Bermejo J.V. , Navas González F.J.
Published: December 2024

Este estudio busca evaluar las relaciones dentro de los registros genealógicos de razas caninas autóctonas en peligro de extinción en las Islas Baleares. Utilizando las Correlaciones del Momento del Producto de Pearson y operando dentro del marco legal del Real Decreto 558/2001 alineado con los estándares de la UE para el reconocimiento de criadores de perros de raza pura en España, se revelaron patrones dentro del registro genealógico. Notablemente, el censo de la Fundación de hembras mostró correlaciones positivas sólidas, resaltando la importancia de una base fundacional sólida, especialmente en las hembras, para una consolidación efectiva de la raza. Por otro lado, las correlaciones negativas con registros auxiliares sugieren un papel disminuido cuando la base fundacional es fuerte. El análisis también revela relaciones robustas dentro de los géneros y fuertes correlaciones con censos totales, indicando enfoques sistemáticos de registro. Sorprendentemente, las hembras en el Registro Auxiliar de Nacimientos carecen de correlaciones, sugiriendo una independencia potencial y subrayando el papel crucial de los censos de hembras en la consolidación de la raza. En conclusión, este análisis de correlación ofrece información valiosa sobre la dinámica del registro genealógico, enfatizando la importancia de una base fundacional sólida, especialmente en relación con los censos de hembras, para la exitosa evolución de las poblaciones caninas en peligro hacia razas estandarizadas. Estos hallazgos proporcionan orientación para la gestión de registros genealógicos y justifican una exploración adicional en categorías de registros específicas, con la advertencia de que, si bien la correlación identifica asociaciones, discernir la causalidad requiere una interpretación matizada y conocimientos específicos del dominio.
Diferenciación Molecular de Razas: Ajuste Fino de Paneles de Marcadores Microsatélites para una Distinción Genética Precisa en Razas Autóctonas de Perros de Baleares
Authors: Alanzor Puente J.M. , Pons Barro Á.L. , González Ariza A. , Marín Navas C. , Concepción Felipe I. , Martínez Martínez M.d.A. , Delgado Bermejo J.V. , Navas González F.J.
Published: December 2024

Este estudio explora la diferenciación genética de las razas caninas autóctonas de las Islas Baleares a través del ajuste fino de paneles de marcadores microsatélites. Se utilizan marcadores microsatélites para desentrañar las complejidades genéticas dentro de las poblaciones, siendo cada marcador una firma molecular única. El estudio investiga la eficacia de estos marcadores en la delineación de razas distintas dentro de la población canina de las Islas Baleares, proporcionando información sobre diversidad genética, informatividad y desviaciones del equilibrio de Hardy-Weinberg. Los marcadores microsatélites examinados forman una narrativa molecular, representando las historias genéticas de las razas caninas baleares. Los resultados revelan marcadores específicos con valores consistentes, indicando homogeneidad dentro de las razas, mientras que otros muestran variabilidad, especialmente en razas con menor diversidad genética. La discusión enfatiza la selección de marcadores para un panel integral, considerando las sutilezas de la diversidad genética en diferentes razas. Los hallazgos contribuyen información valiosa para la gestión, conservación y programas de selección de razas. Los agradecimientos expresan gratitud a las asociaciones de razas por su apoyo, enriqueciendo el estudio con datos esenciales. En general, esta investigación perfecciona nuestra comprensión de las dinámicas genéticas en las razas caninas baleares, informando decisiones para su gestión sostenible.
Efecto de la dosis de un inmunocastrador en hembras Cavia
porcellus sobre los índices productivos
Authors: Bonilla-Remache H. , Guevara-Freire D. , Toalombo-Vargas P. , Delgado J.V. , Navas F.J. , Avilés-Esquivel D.
Published: December 2024

El trabajo de investigación tuvo como objetivo evaluar el
efecto de la dosis de un inmunocastrador en hembras Cavia Porcellus sobre los
índices productivos, el experimento se lo realizó en la Granja PRODUCUY en el Cantón
Salcedo, se utilizaron tres tratamientos: T1 (control), T2 (0.15 cc) y T3 (0.25 cc);
las cuales fueron inoculadas de manera subcutánea el inmunocastrador INNOSURE, se
administró una primera dosis a los 30 días de edad, y la segunda 15 días después, la
evaluación tuvo una duración de 70 días, se registraron valores de ganancia de peso
diaria para el T1 11.1 g, T2 11.4 g, T3 10.7 g, ganancia de peso total de 444.1 g
para el T1, 456.6 g para el T2 y 429.5 g para el T3, con una conversión alimenticia
de 5.0, 4.8 y 5.0 , para cada tratamiento respectivamente, lo cual muestra que no
existió diferencias significativas entre grupos, de la misma manera se identificó el
rendimiento a la canal (%) así: 72.0 para el T1, 72.3% para el T2 y 70.9% para el
T3, y aunque existió diferencias significativas en la variable C/B, el T1 control
como el T2 (0.15 cc) no indicaron pérdidas en el experimento, porque cada dólar
invertido fue recuperado, a diferencia del T3 con un C/B de $0.90 esto debido a que
no existió incremento significativo en los parámetros productivos, la investigación
concluye que la inoculación subcutánea del inmunocastrador INNOSURE en cuyes hembras
no influyó en los parámetros productivos.
Uso de aditivos em silagen de capim-elefante (Pennisetum purpureum, Schum.)
Authors: Queiroz J.P.M. , Lopes I.M.G. , Lima M.D. , Martins Junior V.S. , Oliveira N.J.F. , Almeida A.C.
Published: December 2024

A ensilagem de forrageiras como o capim elefante (Pennisetum purpureum, Schum), tem sido considerada a principal ferramenta para a conservação de alimentos, visando garantir o seu valor nutricional por maiores períodos. Entretanto, alguns fatores ajudam a diminuir a eficiência do processo de ensilagem, sendo necessária a utilização de produtos como os aditivos para promover melhor perfil fermentativo da silagem, resultando em alimentos de qualidade para a nutrição animal. Com isso, objetivou-se com o presente estudo avaliar a influência de aditivos na ensilagem de capim elefante (Pennisetum purpureum, Schum). Os principais aditivos adicionados ao processo de ensilagem são bacterianos, químicos e físicos. Eles melhoram a qualidade da silagem por meio do aumento no número de bactérias benéficas, aceleração da degradação de substrato por ação de bactérias produtoras de ácido láctico e enzimas, inibição do crescimento de populações microbianas prejudiciais, retenção de água, estabilização aeróbia e disponibilização de carboidratos solúveis em concentrações necessárias para aumentar a eficácia no processo de fermentação anaeróbia. Embora os aditivos promovam melhores condições para processo de ensilagem eficiente, é importante considerar parâmetros como tamanho de partícula e compactação, fatores inerentes à planta e o manejo no processo de ensilagem. Portanto, o uso de aditivos é considerado estratégia importante para potencializar o processo de ensilagem em forrageiras, garantindo a manutenção da qualidade da forragem com a redução de perdas, principalmente no valor nutricional do material ensilado.
Failure Modes and Fault Morphology
Authors: Cawood Adam J. , Ferrill David A. , Smart Kevin J.
Published: December 2024

Fault failure modes determine the geometric characteristics of faults and fault zones during their formation and early development. These geometric properties, in turn, govern a wide range of fault processes and behaviors, such as reactivation potential, fault propagation, and growth, and the hydraulic properties of faults and fault zones. Here, we use field data and close-range digital photogrammetry to characterize, in detail, the surface morphology of three normal faults with cm-scale displacements in mechanically layered carbonates of the Cretaceous Glen Rose Formation at Canyon Lake Gorge, Comal County, Texas. Analyses demonstrate complex fault surface geometries, a broad spectrum of slip tendency (Ts) and dilation tendency (Td), and variable failure behavior. We show that (i) fault patches coated with coarse calcite cement tend to have moderate to high dips, low to high Ts, and high to very high Td; (ii) slickensided fault patches exhibit low to moderate dips, moderate to very high Ts, and moderate to high Td; and (iii) slickolite patches exhibit low dips, moderate Ts, and low to moderate Td. Calcite-coated patches are interpreted to record hybrid extension-shear failure, whereas slickensided and slickolite patches record shear and compactional shear failure, respectively. Substantial variability in both Ts and Td across the exposed fault surfaces reflects complex fault morphology that is not easily measured using traditional field techniques but is captured by our photogrammetry data. We document complex fault geometries, with kinematic (displacement) compatibility indicating the various failure modes were active coevally during fault slip. This finding is in direct contrast with the often-assumed concept of faults forming by shear failure on surfaces oriented 30° to σ1. Distinct failure behaviors are consistent with patchworks of volume neutral, volume gain, and volume loss zones along the fault surfaces, indicating that the characterized faults likely represent dual conduit-seal systems for fluid flow.
PROYECTOS INNOVADORES EN EL SECTOR AZUL: IMPULSANDO LA SOSTENIBILIDAD Y EL DESARROLLO ECONÓMICO DE LOS RECURSOS MARINOS
Authors: Vidal Julián Lucía , Paradís Leopori Iris
Published: December 2024

The Spanish region and the Mediterranean basin are positioned as a globally recognised biodiversity hotspot, hosting more than half of Europe’s catalogued species. However, this biological wealth faces serious threats such as terrestrial and marine pollution, habitat destruction and overfishing. In response to this scenario, significant efforts have been undertaken to restructure economic sectors towards sustainable and environmentally friendly models, with the blue sector being particularly prominent. This sector advocates the sustainable exploitation of seas and oceans, facing challenges such as generational change. Faced with this problem, there is a need for innovative initiatives that integrate education and environmental sustainability, using methodologies that attract new generations to professions in the blue sector. In this context, the Centro de Formación Folgado has led several initiatives at European, national and local level, with the aim of addressing the lack of generational change and promoting the sustainable management of marine resources. Its European projects include Blue Careers for a Sustainable Blue Economy (BOUTCAR), an educational alliance to develop training pathways in the blue sector, and Let’s Form Marine Shelters (FOMSHE),  focused on the recovery of the seahorse in the Mediterranean. At the national level, the Emprende Impact project promoted a sustainable entrepreneurship programme aimed at vocational training students. At the local level, the Green Posidonia project has worked on the creation of a pilot plant for the cultivation of Posidonia oceanica and its repopulation, together with educational workshops, while Green Urban Changemakers promoted a more sustainable urban development in the city of Valencia. In addition, the Centre collaborates in other European projects such as BlueCircle, which identifies opportunities within the blue sector, and Let’s Talk Under The Sea (TAUTS), an initiative to promote ocean culture and raise awareness of the effects of underwater noise on marine wildlife. These initiatives reflect a strong commitment to sustainability and innovative education, consolidating the Centro de Formación Folgado as a benchmark in the transformation towards a more sustainable and attractive blue sector for new generations.
Industrial policy and the State of development: to actualization of the notion
Authors: Volynskii A. I.
Published: December 2024

Objective: to analyze the trajectories of industrial policy effective implementation by determining the relevance of key elements of the “development state” model in modern international realities.

   Methods: monographic, historical, abstract-logical, comparative methods.

   Results: the characteristics of the “development states” concept described on the example of some Asian countries allowed their governments to carry out industrial modernization of national economies in a short time and switch to the sustainable economic development trajectory. For many years, the “development state” has been perceived by researchers as part of history. This was determined by the consensus on the existing boundaries of state intervention in the economy. In recent years, the interest of governments in industrial policy has been growing. The implementation of measures withinthe industrial policy gives rise to new challenges to public administration, probably similar to those that the development states have gone through. The author shows that the available formulations of the qualitative characteristics inherent both in the “development state” concept and in some Asian countries in a certain period of their development are significant for the modern theory of public administration in the context of industrial policy measures.

   Scientific novelty: it consists in understanding the concept of the “development state” in the modern context.

   Practical significance: the research provisions and conclusions can be used in the future studies of the economic theory influence on socio-political discourses and political decisions.
Sector trends of total factor productivity: where is the growth potential?
Authors: Kadochnikova E. I. , Bagautdinova N. G. , Khomidov S. O.
Published: December 2024

Objective: to identify industry trends in aggregate factor productivity, labor productivity and capital productivity in economic sectors. The hypotheses are: there is a continuing slowdown in aggregate factor productivity in the Russian economy sectors; there is a gap in aggregate factor productivity in various complexes of industries.

   Methods: Cobb–Douglas production function, multiple regression, Domar aggregation, Gini coefficient, graphical visualization.

   Results: the study revealed a more efficient use of labor resources in contrast to capital, the latter being accumulated everywhere. The highest increase in labor productivity was noted in financial and insurance activities, manufacturing industries, professional, scientific and technical activities. There is a cyclical dynamics of aggregate factor productivity, its most stable growth and a positive cumulative technological shift marked from 2017 until 2021. They are observed in the manufacturing and investment complexes of the Russian economy (financial and insurance activities), and in agriculture.A decrease in total factor productivity was found in the mining industry, transportation and storage, hotels and catering, construction, education, and healthcare.

   Scientific novelty: it consists in a change in the total factor productivity and the total technological shift in the context of sectors and complexes of sectors of the Russian economy from 2011 to 2021.

   Practical significance: the study results can be used for the policy of stimulating internal sources of economic growth, to improve sectoral recommendations of innovation policy.
Institute of bankruptcy in the Russian Federation: establishment and ways of development of the legal provision
Authors: Belousov A. L.
Published: December 2024

Objective: to study the issues of regulation of bankruptcy relations and to determine the ways of further development of the legal field in this sphere.

   Methods: historical method, logical and structural analysis, system-functional approach, formal-legal method.

   Results: the article considers formation of the bankruptcy institute in the Russian Federation. In addition, the modern state of legal support in this field is analyzed. The peculiarities of the Russian model of bankruptcy regulation are outlined. Further, the author emphasizes the current problems in the regulation of bankruptcy relations in the Russian Federation. In particular,the author notes that the procedures aimed at restoring the solvency of debtors are not in demand in practice. The study also emphasizes the problem of a relatively low percentage of satisfied creditors’ claims as a result of bankruptcy procedures. An assessment is given of the current project of changing the legal field in this area proposed by the legislator. The ways of further development of bankruptcy legislation are defined.

   Scientific novelty: consists in the complex nature of the study of bankruptcy relations. In particular, the research provides a new development of theoretical provisions, as well as practical recommendations to improve legal regulation and increase the effectiveness of the bankruptcy institute. It is established that today there is a smooth transition from the pro-debtor model of bankruptcy relations, which was previously dominating, to a more balanced mechanisms of insolvency regulation from the viewpoint of creditor and debtor interests. It is also argued that it is necessary to abandon the financial rehabilitation and external management procedures, which actually do not work in practice, and to replace them with a single rehabilitation procedure aimed at restoring the debtor’s solvency.

   Practical significance: a certain theoretical basis was formed, which is necessary both for researching the essence of the bankruptcy institute in the Russian Federation and for developing proposals to adjust regulatory policy in this area in the future.
Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy
Authors: Shimazaki Rui , Saito Yoshihiko , Awaya Tomonari , Minami Narihiro , Kurosawa Ryo , Hosokawa Motoyasu , Ohara Hiroaki , Hayashi Shinichiro , Takeuchi Akihide , Hagiwara Masatoshi , Hayashi Yukiko K , Noguchi Satoru , Nishino Ichizo
Published: December 2024

Background
Sarcoglycanopathies (SGPs) are limb-girdle muscular dystrophies (LGMDs) that can be classified into four types, LGMDR3, LGMDR4, LGMDR5, and LGMDR6, caused by mutations in the genes, SGCA, SGCB, SGCG, and SGCD, respectively. SGPs are relatively rare in Japan. This study aims to profile the genetic variants that cause SGPs in Japanese patients.
Methods
Clinical course and pathological findings were retrospectively reviewed in Japanese patients with SGP. Genetic analyses were performed using a combination of targeted resequencing with a hereditary muscle disease panel, whole genome sequencing, multiplex ligation-dependent probe amplification, and long-read sequencing. The structures of transcripts with aberrant splicing were also determined by RT-PCR, RNA-seq, and in silico prediction.
Results
We identified biallelic variants in SGC genes in 53 families, including three families with LGMDR6, which had not been identified in Japan so far. SGCA was the most common causative gene, accounting for 56% of cases, followed by SGCG, SGCB, and SGCD, at 17%, 21%, and 6%, respectively. Missense variants in SGCA were very frequent at 78.3%, while they were relatively rare in SGCB, SGCG, and SGCD at 11.1%, 18.2%, and 16.6%, respectively. We also analyzed the haplotypes of alleles carrying three variants found in multiple cases: c.229C > T in SGCA, c.325C > T in SGCB, and exon 6 deletion in SGCG; two distinct haplotypes were found for c.229C > T in SGCA, while each of the latter two variants was on single haplotypes.
Conclusions
We present genetic profiles of Japanese patients with SGPs. Haplotype analysis indicated common ancestors of frequent variants. Our findings will support genetic diagnosis and gene therapy.
Proline isomerization is a key modulator of the bacterial IsdB/hemoglobin interaction: an Atomic Force Spectroscopy study
Authors: Pancrazi Francesca , Bei Omar , Tocco Francesco Lavecchia , Marchetti Marialaura , Campanini Barbara , Cannistraro Salvatore , Bettati Stefano , Bizzarri Anna Rita
Published: December 2024

Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven virulence factor that can be targeted for the design of antibacterial molecules or vaccines. Recent single-molecule experiments on IsdB interaction with cell adhesion factors revealed an increase of the complex lifetime upon applying a stronger force (catch bond); this was suggested to favor host invasion under shear stress. An increased bond strength under mechanical stress was also detected by Atomic Force Spectroscopy (AFS) for the interaction between IsdB and Hb. Structural information on the underlying molecular mechanisms at the basis of this behaviour in IsdB-based complexes is missing. Here, we show that the single point mutation of Pro173 in the IsdB domain responsible for Hb binding, which weakens the IsdB:Hb interaction without hampering heme extraction, totally abolishes the previously observed behavior. Remarkably, Pro173 does not directly interacts with Hb, but undergoes cis-trans isomerization upon IsdB:Hb complex formation, coupled to folding-upon binding of the corresponding protein loop. Our results suggest that these events might represent the molecular basis for the stress-dependence of bond strength observed for wild type IsdB, shedding light on the mechanisms that govern the capability of SA to infect host cells.