bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects of Plant Derived Bioactive Compounds as Nanoparticles for Biotechnological Applications
Authors: Bano Naushin , Izhar Syed Khalida , Gupta Anamika , Zaheer Mohd. Rehan , Roohi
Published: April 2024

Nanoparticles bestow beneficial impacts on plants, specifically in increasing
photosynthetic capacity and germination rate, pesticide delivery, managing pathogenicity
and enhancing nutrient supply. The nanoparticles produced from the medicinal plant extracts
are identified as an exceptional applicant in nanomedicine, cosmetics, and agriculture
for the treatment of diseases as antimicrobial, antioxidant and anticancer agents, etc.
Plant extracts actually have bioactive metabolites that provide therapeutic potential
against a variety of diseases. Herein, we review the production of bioactive compounds
from leaves, roots, seeds, flowers and stems. We further summarize the different methods
for obtaining plant extracts and the green technologies for the synthesis of nanoparticles
of plant derived bioactive compounds. Biotechnological aspects of these synthesized nanoparticles
are also added here as highlights of this review. Overall, plant derived nanoparticles
provide an alternative to conventional approaches for drug delivery as well and
present exciting opportunities for future research on novel areas. We explore patent
applications for novel plant-derived nanoparticle technologies, highlighting their
potential in various fields.
A Novel Detection of Cerebrovascular Disease using Multimodal Medical Image Fusion
Authors: Paul Sudip , Jain Shruti
Published: April 2024

Background:

Diseases are medical situations that are allied with specific signs and
symptoms. A disease may be instigated by internal dysfunction or external factors like pathogens.
Cerebrovascular disease can progress from diverse causes, comprising thrombosis, atherosclerosis,
cerebral venous thrombosis, or embolic arterial blood clot.

Objective:

In this paper, authors have proposed a robust framework for the detection of cerebrovascular
diseases employing two different proposals which were validated by use of other datasets.

Methods:

In proposed model 1, the Discrete Fourier transform is used for the fusion of CT and
MR images which was classified them using machine learning techniques and pre-trained models
while in proposed model 2, the cascaded model was proposed. The performance evaluation
parameters like accuracy and losses were evaluated.

Results:

92% accuracy was obtained using Support Vector Machine using Gray Level Difference
Statistics and Shape features with Principal Component Analysis as a feature selection
technique while Inception V3 resulted in 95.6% accuracy while the cascaded model resulted in
96.21% accuracy.

Conclusion:

The cascaded model is later validated on other datasets which results in 0.11% and
0.14% accuracy improvement over TCIA and BRaTS datasets respectively.
Misuse of Authority: Ethical Concerns
Authors: Zaheer Tahreem , Mehmood Naila Nasir , Ahmed Syed Hashaam
Published: April 2024

Pakistan is confronted with one of the most common ethical concerns that is
prevalent worldwide - the common occurrence of abuse of authority. This chapter
primarily delves into a pervasive ethical issue in Pakistan, as well as globally – the
widespread abuse of authority. Through a comprehensive literature review and
qualitative survey methods, this chapter examines instances of authority abuse across
different sectors, with a primary focus on the police department, the political system,
and workplace misconduct. It seeks to shed light on the factors contributing to such
misuse, its consequences, and potential preventive measures. In recognizing the extent
of authority abuse, this chapter underscores the urgency for our society to devise
effective strategies to combat this unethical behavior, emphasizing the importance of
ethical conduct in positions of power.
Unethical Decision Making at Workplace: Psychological Issues and Ethics
Authors: Khalid Anibah , Babar Samra , Malik Shiza
Published: April 2024

People find it hard to make ethical decisions in their lives. They often make
unethical decisions in certain situations due to several factors and end up with dire
consequences. In recent years, organizations have been applying different strategies to
create an ethical atmosphere in the workplace. In this chapter, we have discussed
unethical decision making at the workplace, its causes, consequences, and how this
dilemma can be dealt with. Special insights will be drawn upon the impact of unethical
decision making on the behavior of people. The purpose of this data is to elaborate on
the importance of ethical decision making in every profession to run the workplace
smoothly without causing psychological and behavioral stress among the task forces.
Unethical Behavior of Pharmaceutical Companies
Authors: Batool Syeda Faria , Qureshi Sara , Malik Shiza
Published: April 2024

Malpractices of pharmaceutical companies in marketing their products are
widely becoming common. These practices not only involve the pharmaceutical
companies but are also associated with other professions. These may include nurses,
doctors, technicians, pharmacists, and cosmetic sellers, among others. Traders of
pharmaceutical companies give these professionals handsome incentives and subtly ask
them to market their products without letting them know about the actual performance
of the product whether it is a drug, cosmetic product, food, etc. Such products can have
many damaging side effects ranging from minor to major. They can even sell their
low-cost products by doubling the actual retail price just to have some extra money.
Such practices compromise the doctoral-patient relationship of trust and mutual
understanding and thus raise questions on the sanctity of the healthcare system. This
piece of literature has been created to discuss issues related to the unethical behavior of
pharmaceutical companies. The data shed light on the required steps for mainstreaming
ethical practices. It is required to implement proper ethical guidelines within each
sector of healthcare, primarily the pharmaceutical domain.
Workplace Harassment (Bullying) and its Health and Ethical Concerns
Authors: Arshad Maleeha , Abbas Maryam , Malik Shiza
Published: April 2024

One of the pressing issues in any workplace environment is not only
optimizing working and maintaining a healthy environment of the workplace but also
keeping a check and balance of employee relationships and maintenance of peerless
interaction among the employee, head, and other staff members of the organization.
Workplace harassment is one of the imperative issues in the workplace throughout the
world, regardless of geographical discrimination. Obnoxious and biased conduct is
lawfully considered harassment when it is distressing enough to adversely affect a
workplace habitat. There is a general lack of awareness among the masses in a working
environment about workplace harassment; people often fail to recognize the
harassment until and unless they find themselves at the receiving end of extreme
delinquency and abuse. This chapter will elaborate upon the ethical concerns
underlying workplace attitude with special reference to bullying in the workplace and
its outcome. Some ways to tackle these abnormalities will also be made part of the
discussion to let the readers know the right way out, whether they are the boss, the
subordinate or a colleague suffering from bullying at a workplace.
Ethical Issues Related to Human Radiation Experiments
Authors: Tahir Mehreen , Abbas Zehra , Malik Shiza
Published: April 2024

Human radiation experiments have been utilized for a long time for dealing
with healthcare complications. Their usage is undeniably acceptable for diagnosis,
treatment, and preventive and detection processes. However, the dilemma attached to
unethical practices in radiation experiments compromises its beneficiary accounts. The
health sector throughout the world is facing the dilemma attached to radiation
experiments. The problems associated with unwanted radiation exposure and excessive
and unnecessary application of radiation experiments are a major concern for scientific
and healthcare authorities to deal with. This chapter gathers data regarding ethical
issues that arise out of such human radiation experiments. It is required to learn lessons
from case studies and research and to devise better experiments for future radiation
experiments.
Euthanasia and Ethics: ‘The Good Death’ Debate
Authors: Munawer Sabahat , Fatima Rizwana , Sohail Areej , Qureshi Zunaira , Malik Shiza
Published: April 2024

Euthanasia is a burning ethical issue as some people have an opinion that it
is better for a person to die than suffer from a painful and incurable disease. Murderers
hide behind euthanasia and cause the death of a human no matter what the reason is
against human dignity. This chapter revolves around the topic of critical ethical issues
pertaining to the ‘end of life’, which includes euthanasia and physician-assisted suicide
(PAS). Information that can help society cope with this ethical issue (Euthanasia) is
explained, as nowadays, people are more careless towards weak, old and ill people. The
concept of long-term care for terminally ill patients seems to have become very rare,
and people have started considering death better than life. This piece of information
will help create public understanding regarding euthanasia as a professional, ethical
issue, its prevalence across the world, causative factors, and some strategies to
overcome euthanasia.
Defining the Moral Status of an Embryo? Or Defying the Moral Status of a Woman?
Authors: Sehar Bakhtawar , Shahid Syeda Zahra
Published: April 2024

Embryonic Stem Cells (ESC) are pluripotent cells that give rise to all cell
types and are used for cell replacement and regenerative therapies. However, ethical,
social, and legal controversies have questioned the morality of the procedures to obtain
ESC lines, and the moral status of an embryo is oscillating in the debate about the
origin of life, whether it originates at the totipotent stage or at the point of syngamy.
Ironically, the moral status of women is also being defied by inadequate informed
consent for medical procedures and their life-threatening consequences. In response to
the ESC controversy, an alternate approach of using low-grade embryos for obtaining
ESC lines has been proposed. This study aims to define the moral status of an embryo,
question the defined status of a woman, and find new ethical-based medical procedures
to obtain ESC lines.
Human Cloning- A Far-Fetched Idea or a Genetic Disaster?
Authors: Khurazmi Fatima , Malik Shiza
Published: April 2024

The world is a natural heritage where everything is revolving in a balanced
way. The whole universe is moving in a way that is not disturbing the flow of life, the
stars, the moon, the planets, seasons, and the process of life and death. But when
something disrupts the nature of this cycle, the outcome of that will be seen in the
world as a whole. With the evolution of science, man has made and produced things
that people were not aware of. However, with every advantage comes its drawbacks
and disadvantages. Similarly, the process of human cloning was once a farfetched idea
but now has become a genetic disaster for humans. But, many oppose this and talk in
favor of human cloning, mostly those who can afford it. However, if one looks at all
the aspects of human cloning, then it is a genetic disaster. To create or not to create is
the question. Do they serve the human race by human cloning? This chapter has been
devised to answer this question and to elaborate on the ethical concerns that arise out of
human cloning experiments. The purpose is to make the reader aware of the sensitivity
of this medical topic and to elaborate on what limitations could be there to deal with in
such medical procedures.
التنمر الوظيفي مظاهره و أسبابه
Authors: Mohammed Kazhal Hussein
Published: April 2024

هدفت الدراسة الحالية الى معرفة مظاهر سلوكيات التنمر الوظيفي في بيئة العمل وماهي أكثر أشكالها انتشاراً بين الموظفين في مديرية تربية الغرب في مدينة السليمانية، وكذلك التعرف على اسباب انتشار هذه الظاهرة بين الموظفين، وللأجابة على هذه التساؤلات اعتمدت الباحثة على المنهج الوصفي التحليلي للتعرف على مظاهر و أسباب ظاهرة التنمر الوظيفي سعياً للوصول الى النتائج المتعلقة بمتغيرات الدراسة من خلال استخدام الاستبيان كأداة لجمع البيانات وتوصلت الدراسة الى واقع انتشار ظاهرة التنمر بين الموظفين في بيئة عمل هذه المؤسسة بأشكالها المختلفة الجسدية و اللفظية و الوظيفية وبينت عدة أسباب و عوامل تدفع بالشخص المتنمر لممارسة سلوكيات التنمر والعنف ضد زملائه في العمل، وأوصت الدراسة بأيجاد بيئة عمل آمنة للموظفين لتحسين ادائهم الوظيفي و توعيتهم بمفهوم التنمر وآثاره السلبية على الفرد و المؤسسة و المجتمع عامة واتخاذ اجراءات عقابية رادعة للحد من الظاهرة واجراء المزيد من الدراسات حول هذه الظاهرة و علاقتها بمتغيرات و عوامل اخرى.
Identifying Depression Through Machine Learning Analysis of Omics Data: Scoping Review
Authors: Taylor Brittany , Hobensack Mollie , Niño de Rivera Stephanie , Zhao Yihong , Masterson Creber Ruth , Cato Kenrick
Published: April 2024

Background

Depression is one of the most common mental disorders that affects >300 million people worldwide. There is a shortage of providers trained in the provision of mental health care, and the nursing workforce is essential in filling this gap. The diagnosis of depression relies heavily on self-reported symptoms and clinical interviews, which are subject to implicit biases. The omics methods, including genomics, transcriptomics, epigenomics, and microbiomics, are novel methods for identifying the biological underpinnings of depression. Machine learning is used to analyze genomic data that includes large, heterogeneous, and multidimensional data sets.

Objective

This scoping review aims to review the existing literature on machine learning methods for omics data analysis to identify individuals with depression, with the goal of providing insight into alternative objective and driven insights into the diagnostic process for depression.

Methods

This scoping review was reported following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines. Searches were conducted in 3 databases to identify relevant publications. A total of 3 independent researchers performed screening, and discrepancies were resolved by consensus. Critical appraisal was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross-Sectional Studies.

Results

The screening process identified 15 relevant papers. The omics methods included genomics, transcriptomics, epigenomics, multiomics, and microbiomics, and machine learning methods included random forest, support vector machine, k-nearest neighbor, and artificial neural network.

Conclusions

The findings of this scoping review indicate that the omics methods had similar performance in identifying omics variants associated with depression. All machine learning methods performed well based on their performance metrics. When variants in omics data are associated with an increased risk of depression, the important next step is for clinicians, especially nurses, to assess individuals for symptoms of depression and provide a diagnosis and any necessary treatment.
A Survey of Demographics and Treatments in Melanoma Case Reports: Retrospective Bibliometric Analysis
Authors: O'Hagan Ross , Ngandjui Jessie , Ungar Benjamin , Ungar Jonathan , Gulati Nicholas
Published: April 2024

Melanoma case reports show variations in treatment by age and sex.
Unveiling Gendered 3MT Presentations: A Corpus-based Analysis of Evaluative Language Important
Authors: Zhang Shihui , Wang Qian
Published: April 2024

Originating at the University of Queensland (UQ), the 3 Minute Thesis (3MT) has evolved into a pivotal form of academic communication. The linguistic resource important is often employed by presenters to underscore the significance of specific concepts, discoveries, or viewpoints, revealing their epistemic and evaluative stance. By constructing a corpus encompassing all award-winning 3MT presentations from UQ, with a particular focus on the usage of important and its related words, we found that (1) there was no statistically significant gender-based discrepancy in the frequency of employing important; (2) male presenters employed important in isolation, while their female counterparts opted for more expansive terms such as significant or crucial, encompassing a broader range of interpretations; (3) in terms of contexts, female speakers tended to extend their use of these terms beyond academic contexts, linking them with lived experiences more often than male presenters. The observed patterns related to how male and female presenters convey the importance of their research can enhance our comprehension of the subtle ways in which language mirrors and perpetuates gendered norms and expectations. More importantly, they may facilitate progress towards fostering more inclusive and equitable academic environments.
Franco Moretti’s Interdisciplinary Approach and its Influence on Foreign Literature Studies in China
Authors: Chen Shuping
Published: April 2024

Western literary theorist Franco Moretti’s researches are featured with interdisciplinarity. His approach began with the conceptual model of “world literature”, followed by the methodology of “distant reading”, and ended with the practice of “computational criticism”. This paper aims to explore the dynamic interaction between Darwin’s evolutionary theory and Wallerstein’s world-systems analysis, as well as the interplay between close reading and distant reading, and the dialogue between traditional criticism and computational criticism. With the popularization of the Internet, the revolution of information technology and the wave of globalization, the categorization of disciplines with distinct barriers can no longer meet the complexity of modernization, and the call for interdisciplinary integration is constantly heard. Nevertheless, interdisciplinary research is in urgent need of theoretical framework and practical guidance for reference. This paper seeks to contribute to the interdisciplinary study of foreign literature in China within the purview of “new liberal arts”.
Comparative Analysis of the Productivity and Efficiency of Cluster and Individual Farming in West Arsi Zone of Oromia
Authors: Bati Beriso
Published: April 2024

The main objective of this study was to compare the productivity and efficiency of clustered and individual farming; to identify factors affecting clusters farming practice and to know the view/perception of farmers for clustered farming approach in West Arsi zone. To conduct the study, primary data was collected from 152 randomly selected household heads through semi-structured questionnaire. Secondary data were also collected from different sources including CSA, ZOANR, DOANR, and from published and unpublished sources to supplement primary data. In this study both descriptive statistics and econometric analysis were employed. The primary data was analyzed using descriptive statistics and stochastic efficiency decomposition method to decompose TE. Stochastic Frontier Approach (SFA) was used for its ability to distinguish inefficiency from deviations that are caused by factors beyond the control of farmers. The productivity of wheat per hectare was 47.17 and 39.042 quintal for cluster and individual farming respectively which is statically significant at 1% level. The study result revealed that the mean of wheat TE was about 78.46%, for cluster farming and 69.25%, for individual farming as the Cobb-Douglas functional form indicate that. As the result of research analysis indicates that, the cumulative sum of farmers’ perception towards the compatibility of cluster farming with the socio-economic situational circumstances was 4.093 suggesting farmers perceive positively that it was compatibility with their socio-economic situational circumstances. The likelihood of farmers to practice cluster farming positively influenced by Sex of HH, age of HH, nearest market center, distance to FTC, participation on field visit and participation in social organization in West Arsi zone. The study suggested that farmer adoption decisions are affected by above mentioned factors and policies addressing each decision process and cross-cutting issues are required to improve farmer participation in cluster farming. In addition, the study suggested the need for policies to discourage land fragmentation and promote, participation in field visit, and strengthening social network of farmers, to increase participation of farmers in cluster farming in the zone.
Indian English Fiction: Seeding to Efflorescence
Authors: Bhat Sami Ullah
Published: April 2024

Indian English literature began as an interesting by-product of an eventful encounter in the late eighteenth century between a vigorous and enterprising Britain and a stagnant and chaotic India. As a result of this encounter as F.W. Bain puts it ‘India a withered trunk… suddenly shot out with foreign foliage’. The first problem that confronts the historian of Indian English literature is to define its nature. The question has been made rather complicated owing to two factors: first this body of writing has, from time to time, been designated variously as ‘Indo-Anglian literature’, ‘Indian Writing in English’ and ‘Indo-English literature’. Secondly the failure to make clear-cut distinctions has also often led to confusion between categories such as ‘Anglo-Indian literature’, literature in the Indian languages translated into English and original composition in English by Indians. Thus, in his A Sketch of Anglo-Indian Literature (1908), E.F. Oaten considers the poetry of Henry Derizio as a part of ‘Anglo-Indian literature’ the same critic in his essay on Anglo-Indian literature in the Cambridge of English Literature includes Toru Dutt, Sarojini Naidu, Rabindranath Tagore and Arvindo Ghose among ‘Anglo-Indian writers along with F.W. Bain and F.A. Steel.
Imperialismo na América Latina: Da onda rosa ao regresso conservador
Authors: Brandão Osório Luiz Felipe , Delgado De David Thomaz
Published: April 2024

A América Latina experimentou na virada do século um período de progressismo inédito em sua história. Ele marcou não apenas uma nova etapa no desenvolvimento dos países, mas serviu de modelo para outras experiências mundo afora. Para uma região inserida na periferia do sistema internacional, em meio à incessante concorrência, o impulso logo começou a ser ceifado pelas potências internacionais, principalmente os Estados Unidos, que patrocinaram direta ou indiretamente a reversão dessa onda por meio do retorno do neoliberalismo ou pela fraude ou pela força. Os mecanismos utilizados e toda a dinâmica envolvida estão imersos dentro do panorama do imperialismo contemporâneo, que é um fator determinante para a explicação dos ciclos e da instabilidade política local. Nesse sentido, partindo de uma compreensão do materialismo histórico e dialético das relações internacionais, este artigo objetiva demonstrar a influência do imperialismo no processo de retrocesso democrático na região, considerando a inserção do continente no sistema capitalista de Estados e a trajetória do capitalismo em âmbito mundial até os dias atuais. Por isso, o trabalho será dividido em três partes: um panorama político regional; a discussão do cenário internacional; e os desdobramentos da expressão hodierna do imperialismo.
Conjuntura político-religiosa na Colômbia e no Brasil
Authors: Castellanos Villamil Nayive
Published: April 2024

O fortalecimento da extrema direita a escala mundial significa um desafio nas análises conjunturais, desde diversos campos do conhecimento, dadas suas multifacetadas apresentações e alcances. Um dos tentáculos desse extremismo o configura a direita cristã neoconservadora, que em interface com grupos econômicos e políticos conseguiu articular-se para engrenar estratégias, narrativas e contrapontos perante toda e qualquer forma de sociabilidade diferente à pautada por esses grupos. Colômbia e Brasil põem sua cota nesses assuntos com diversas tonalidades. Este texto propõe-se esboçar algumas características do contexto político-econômico, como contraste de ambos países, para introduzir sua atual fase de ativismo político-evangélico, a qual difere em nível de desenvolvimento.
Lógica neoliberal de un crimen de Estado en el caso de Ayotzinapa
Authors: Reyes Hidalgo Christian Antonio Christian
Published: April 2024

En este artículo se pretende develar las posibles motivaciones estructurales de la violencia contra los 43 estudiantes de la Normal Rural “Raúl Isidro Burgos” ubicada en la localidad de Tixtla en el estado de Guerrero, también conocida como Ayotzinapa; quienes fueron víctimas de desaparición forzada el 26 de septiembre de 2014, a manos del Estado mexicano, y al mismo tiempo, se intenta comprender el posible nexo entre el discurso de las potencias hegemónicas en el marco de la llamada cooperación para el desarrollo, pero bajo la premisa de la implementación de políticas de corte neoliberal, mismas que son adoptadas y replicadas por gobiernos colaboracionistas, bajo un discurso de progreso, desarrollo y modernidad, empleando cualquier mecanismo para mantenerse, incluso la ejecución de graves violaciones a los derechos humanos.
Maniac Management System
Authors: Dandotiya Dr. Nidhi
Published: April 2024

Abstract: Criminal psychology has always been a topic that has come into immense roar these days because of the increase in crimes all around the globe, it is impossible to make out who is iniquitous in today’s time, a person sitting next to you in a local transport can be as dangerousto you as a murderer/rapist sitting inside a jail, hence the aim of this work is to find out the mechanics inside a criminals mind before and after committing a crime so that we can curb thenumber of criminals around the world by understanding their workings.
Achieving Agility through Auto-Scaling: Strategies for Dynamic Resource Allocation in Cloud Computing
Authors: Vemasani Preetham , Vuppalapati Sai Mahesh , Modi Suraj , Ponnusamy Sivakumar
Published: April 2024

Abstract: Auto-scaling is a crucial aspect of cloud computing, allowing for the efficient allocation of computational resources in response to immediate demand. This article delves into the concept of auto-scaling, its key components, and the strategies used to effectively manage resources in cloud environments. This study emphasizes the importance of auto-scaling in the cloud computing landscape by exploring its benefits, including cost efficiency, performance optimization, high availability, and scalability [1]. The article explores the various factors to consider when implementing scaling policies, such as selecting the right approach for scaling, whether it be predictive or reactive and the availability of auto-scaling services provided by major cloud platforms like Amazon Web Services (AWS), Google Cloud Platform (GCP), and Microsoft Azure [2, 3]. In addition, the paper addresses the challenges and complexities related to configuring auto-scaling systems, cost management, and latency in resource provisioning [4]. The article also showcases case studies that illustrate the successful implementation of auto-scaling in different industries, along with valuable insights and recommended approaches [5]. Lastly, this paper delves into future trends and research directions in auto-scaling techniques, integration with emerging technologies, and potential research areas [6].
Adaptive Honking System for Smart Cities Using IOT
Authors: Madke Prof. Nilesh B.
Published: April 2024

Abstract: This project has an aim to control the horn volume in cities and also in restricted area as such schools, parks, hospitals, old age homes, college, government offices and in speed limited areas etc. Some peoples are driving vehicles in a high speed and create noise of horn of vehicle. So the police are not able to monitor all those things. Driver does control the speed of vehicle at places. This paper provides a way for how to control the speed of vehicle and control the noise of horn without harming others. This project has an aim to control noise of horn automatically. The speed of any vehicles will be detected using accelerometer if the speed of vehicle is exceed in honking zone then the buzzer can buzz and get alert to driver about . cities and also in restricted area as such schools, parks, hospitals, old age homes, college, government offices and in speed limited areas etc. Nowadays in a fast moving world all the peoples are not have self-control. Controls are taken automatically by the use of electronic system. In this project we use GPS for indicating the nearby honking zone. Speed is measured by the help of accelerometer in the vehicle. The controller compares the speed. If it exceeds the limited speed the pizzobuzzer buzz and alerts the driver and controls taken automatically by driver and when vehicle is near at honking zone the switch can automatically decrease the volume of horn if it on. In this way our smart honking zone for smart cities project will be perform
Language Games- The Great Medium to Learn English Language
Authors: Abidi Aeda
Published: April 2024

Abstract: The present study aims to explore the innumerable possibilities that language games create for learning a language as a supplementary material. Language games are ideal for teaching and enhancing vocabulary of ESL learners. Take something as simple as a riddle-in case the teacher asks a riddle in a second Language class, the learners are very interested in listening to it and answering it. The riddle brings enthusiasm to an otherwise silent class. In addition to it, the learners are learning the nuances of the language like figurative language unconsciously or sub –consciously. Another mind sport is quiz that can be used to teach elements of language like grammar and vocabulary and their usage. Games can also be designed to cater to the needs of the learners and enable them to enhance their language skills i.e. listening, speaking, reading and writing. A story telling activity can eventually lead to enhancement of listening skill. The chain story building technique can be used to hone the speaking skill. Similarly, cross word puzzles can also be used to remember a few facts from a lesson just read. An activity like a write up on a topic like my favourite offline/online game can enhance the writing skills of the learners. Thus, it can be concluded that language games can be used as a supportive method for teaching and learning English in ELT classroom.
21st-Century Digital Literacy: Using Information Technology to Empower People
Authors: Kaur Ms. Jasmeen
Published: April 2024

Abstract: A vital skill set for people to survive and prosper in an increasingly digital environment, digital literacy has arisen in the quickly changing 21st century. This abstract examines the value of digital literacy by looking at information technology (IT) and how it has affected modern society. It explores the complexity of digital literacy, including not just the technical know-how to utilize digital tools and technology but also the social, ethical, and intellectual aspects that are essential for productive digital participation. The elements of digital literacy, such as media literacy, information literacy, communication skills, critical thinking, and problem-solving abilities, are examined in this abstract, which draws on theoretical frameworks and actual studies. In addition to giving people access to a wealth of materials, communication channels, and chances for learning and cooperation, it also examines how information technology might be used as a facilitator to improve digital literacy. This abstract also discusses the difficulties and obstacles that hinder the adoption of digital literacy, including the digital gap, unequal access to technology, and concerns of digital inequality. It highlights how crucial it is for everyone to have equal access to digital resources and how important it is for governments, schools, and community groups to work together to promote digital inclusion and close the digital gap. Furthermore, the revolutionary power of digital literacy is highlighted in this abstract across a number of fields, such as political participation, job placement, schooling, and medical services. In order to promote lifelong learning and empowerment, it addresses cutting-edge strategies and best practices for incorporating digital literacy into seminars and workshops, community initiatives, and school curriculum. As a conclusion, this abstract emphasizes how critical digital literacy is in the twenty-first century and how it shapes people's ability to prosper in a society that is becoming more technologically advanced and linked. The statement highlights the need of coordinating endeavors to advance digital literacy programs and provide fair access to digital assets, ultimately enabling people to engage completely in the digital community.
Finding Harmony Amidst the Hustle: Balancing Work and Life and Employee Commitment in Private Healthcare
Authors: Datta Auadhati , Narayanamma Dr. P. Lakshmi
Published: April 2024

Abstract: This research looks at how job satisfaction and work-life balance are perceived by hospital workers and how it affects their commitment to the hospital. Researchers employed questionnaires and took into account any gender disparities in order to get a thorough understanding. The study postulated that job satisfaction and work-life balance would together have an impact on staff commitment, drawing on earlier studies. Fascinatingly, the survey's findings indicated that dedication, job satisfaction, and work-life balance were all at moderate levels. One important discovery was the obvious connection between job happiness and work-life balance. Interestingly, commitment was positively correlated with the effects of work on personal life as well as the reverse (personal life on work). Lastly, the research determined how work-life balance manifested itself for men and women, as well as gender disparities in commitment levels
A Review on Crack Detection in Wind Turbine Blade
Authors: Madhav Pratham S. , Matavkar Darshan D. , Mayekar Nikhil S. , Parsekar Mandar M.
Published: April 2024

Abstract: It was observed that there is a need to reduce of maintenance and operational cost of Wind Energy conversion System. The most efficient way of reducing this cost would be to carry out Non-destructive techniques (NDT) and continuously monitor the condition of the system. This allows for early detection of the blade Cracking or damage, minimizing downtime, and maximizing productivity. The importance of condition monitoring and fault diagnosis in WECS (blades) and keeping in mind the need for future research, this paper is intended as a brief status describing different type of faults, methods of detection and future aspects
Smoke-Eye An AIML Based De-Smoking and De-Hazing System
Authors: K Shahida Begum , K Afsha Muskan , Tabassum Syeda Ayesha , Aiman Ummai
Published: April 2024

Abstract: Indoor fire incidents pose significant challenges to first responders, often due to the presence of smoke and haze, which severely limit visibility. Delays in response times and increased risks to both responders and victims are common consequences. To address this critical issue, the "Smoke-Eye" project introduces an AI-ML based de-smoking/de-hazing system designed to enhance visibility during indoor fire hazards. The primary objectives of "Smoke-Eye" include the development of a smoke and haze detection module, the implementation of advanced image dehazing algorithms, and the optimization of video processing.
Development of e-worksheet based on search, solve, create, and share (SSCS) Islamic context to improve science process skills on excretory system material
Authors: Elvanuari Tika Audyta , Zulfiani Z. , Rosyidatun Eny Supriyati
Published: April 2024

Electronic student worksheets (e-worksheet) are needed as alternative teaching materials in learning. This study aims to produce teaching materials in the form of e-worksheet based on Search Solve Create and Share (SSCS) Islamic context to improve science process skills on class XI excretory system material that is worthy of the results of validity, responses of students and biology teachers. This research was conducted at MAN 1 Bogor. The research model used is a 4D model (Define, Design, Develop, Disseminate), but in research only to the development stage (Develop). The e-worksheet teaching materials developed are tested for validity. The results of validity tests by design and media experts obtained 89% in the very decent category, material expert assessments obtained 84% in the very feasible categories, and expert assessments of Islamic religious education obtained 100% in the very feasible categories. The results of student responses obtained percentages of 89% in limited trials and 89.7% in expanded trials. Based on the findings of the research results, it can be concluded that E e-worksheet based on Search Solve, Create and Share (SSCS), an Islamic context to improve science process skills on the excretory system material developed, is very feasible to be used and applied to biology learning.
Perspectives of Interfaith Figures on Religious Moderation in an "Intolerant City": A Study in Padang
Authors: Halim Ismail , Faisal Faisal
Published: April 2024

This study aims to examine the perspectives of interfaith leaders in Padang City on religious moderation. This study uses a naturalistic qualitative approach, with data collection techniques of in-depth interviews with Muslim, Catholic, Christian, Hindu, Buddhist and Confucian religious leaders. This study focuses on four pillars or indicators of religious moderation, namely commitment to nation and state, tolerance, non-violence, and accommodation to local culture. The results found that interfaith leaders in Padang City strongly support the concept of religious moderation because religious moderation is believed to be relevant to the teachings of each religion, such as the common ideals of building the life of the nation and state for mutual progress, living in harmony amid differences, rejecting acts of violence in the name of religion, and maintaining and respecting local culture. This study also found that interfaith leaders as religious elites spread the values of religious moderation to each of their followers. The interfaith leaders also agreed that Padang City is conducive in terms of interfaith relations, even though the city is ranked low in the tolerance index by a number of research institutions
MAXIMIZING MILLENNIAL JOB SATISFACTION: THE KEY ROLES OF MEANINGFUL WORK AND RESILIENCE
Authors: Muchtadin Muchtadin
Published: April 2024

The millennial generation has different characteristics from previous generations. It is important for organizations to know the characteristics of millennials because they can bring advantages and disadvantages to the organization. This research aims to determine the magnitude of the influence of learning agility, meaningful work, and resilience on job satisfaction of the millennial generation. A quantitative causality design was applied in this research. Respondents were 100 millennial workers in Indonesia. Research data was taken via Google Form via Facebook, WhatsApp and Linked-in. Data analysis was carried out using the PLS SEM method. The research results show that learning agility has no effect on millennial job satisfaction. Meaningful work has a significant positive effect on millennial job satisfaction. Resilience has a significant positive effect on millennial job satisfaction. Future research can limit respondents to one sector, such as private and public. Future researchers can use the mediation of meaningful work and resilience on the influence of learning agility on job satisfaction. This research contributes to efforts to increase job satisfaction of the millennial generation through learning agility, meaningful work and resilience.
The role and importance of civil initiatives in local governance
Authors: Bajrami Iliriana , Bajrami Taulant
Published: April 2024

Local governance is closely related to democracy and provides a central position to the participation of citizens in decision-making, where the perspectives of different authors such as political scientist Robert Dahl emphasized that democracy must offer equal and proper opportunities for citizens’ participation in decision-making (Forrester & Sunar, 2011). The purpose of this paper is to create a fair overview of the real condition of citizens’ involvement in local government decision-making processes, by highlighting the necessity to adapt local government to the real needs of citizens, which facilitates their lives within the municipalities. The review of literature and development of qualitative research was the methodology applied within this study. During the development of this study, surveys were also conducted with citizens and other institutional stakeholders with a key role in local governance. The findings of this paper indicated that municipal bodies have made minimal efforts to inform citizens about their opportunities and raise awareness regarding the importance of activism in decision-making, as substantiated by the questionnaire outcomes. On this occasion, it was also observed that there is a low level of citizens’ inclination to participate in public gatherings aimed at influencing municipal governance activities.
Successful Use of Granulocyte Transfusion Therapy as a Bridge to Hematopoietic Stem Cell Transplant in a Child with Aplastic Anemia and Refractory Perirectal Abscess
Authors: Dang Mary , Rubbab Beenish , Kwon Jeannie , Noland Daniel , Sue Paul K. , Dickerson Kathryn
Published: April 2024

This brief report describes the use of adjuvant granulocyte transfusion
therapy to successfully treat antibiotic refractory proctitis with
perirectal abscess in a child with very severe aplastic anemia (vsAA).
She was not expected to have imminent neutrophil recovery, which by
current practice guidelines is a prerequisite for the consideration of
granulocyte transfusion; however, the risk of bowel perforation
potentially hastened by conditioning and/or engraftment precluded
curative hematopoietic stem cell transplantation, presenting a
significant treatment conundrum. This case highlights an expanded
clinical indication for granulocyte therapy in a uniquely vulnerable
patient population.
Psilocybin reduces functional connectivity and the encoding of spatial information by neurons in mouse retrosplenial cortex
Authors: Ivan Victorita , Tomas-Cuesta David , Esteves Ingrid , Luczak Artur , Mohajerani Majid , McNaughton Bruce , Gruber Aaron
Published: April 2024

Psychedelic drugs have profound effects on perception, cognition, and
mood. How psychedelics affect neural signaling to produce these effects
remains poorly understood. We investigated the effect of the classic
psychedelic psilocybin on neural activity patterns and spatial encoding
in the retrosplenial cortex of head-fixed mice navigating on a
treadmill. The place specificity of neurons to distinct locations along
the belt was reduced by psilocybin. Moreover, the stability of
place-related activity across trials decreased. Psilocybin also reduced
the functional connectivity among simultaneously recorded neurons. The
5-HT2AR (serotonin 2A receptor) antagonist ketanserin blocked the
majority of these effects. These data are consistent with proposals that
psychedelics increase the entropy of neural signaling, and provide a
potential neural mechanism contributing to disorientation frequently
reported by humans after taking psychedelics.
Development of a proteomic workflow for the identification of heparan sulfate proteoglycan-binding substrates of ADAM17
Authors: Calligaris Matteo , Spanò Donatella , Mueller Stephan , Bonelli Simone , Pinto Margot Lo , Zito Giovanni , Blobel Carl , Lichtenthaler S , Troeberg Linda , Scilabra Simone
Published: April 2024

Ectodomain shedding, which is the proteolytic release of transmembrane
proteins from the cell surface, is crucial for cell-to-cell
communication and other biological processes. The metalloproteinase
ADAM17 mediates ectodomain shedding of over 50 transmembrane proteins
ranging from cytokines and growth factors, such as TNF and EGFR ligands,
to signaling receptors and adhesion molecules. Yet, the ADAM17 sheddome
is only partly defined and biological functions of the protease have not
been fully characterized. Some ADAM17 substrates (e.g. HB-EGF) are known
to bind to heparan sulfate proteoglycans (HSPG), and we hypothesised
that such substrates would be under-represented in traditional secretome
analyses, due to their binding to cell surface or pericellular HSPGs.
Thus, to identify novel HSPG-binding ADAM17 substrates, we developed a
proteomic workflow that involves addition of heparin to solubilize
HSPG-binding proteins from the cell layer, thereby allowing their mass
spectrometry detection by heparin-secretome (HEP-SEC) analysis. Applying
this methodology to murine embryonic fibroblasts stimulated with an
ADAM17 activator enabled us to identify 47 transmembrane proteins that
were shed in response to ADAM17 activation. This included known
HSPG-binding ADAM17 substrates (i.e. HB-EGF, CX3CL1) and 17 novel
HSPG-binding putative ADAM17 substrates. Two of these, MHC-I and IL1RL1,
were validated as ADAM17 substrates by immunoblotting.
Rethinking Ecosystems Disturbance Recovery: what it was or what it could have been?
Authors: Dashti Hamid , Chen Min , Smith Bill , Zhao Kaiguang , Moore David
Published: April 2024

The time it takes for an ecosystem to recover is a key aspect of
environmental disturbance. Conventionally, recovery is defined as a
return to the pre-disturbance state, assuming ecosystem stationarity.
However, this view does not account for the impact of external forces
like climate change. We propose a counterfactual approach, viewing
recovery as the state the ecosystem would achieve without the
disturbance. This redefines recovery time as the period until the
ecosystem reaches its counterfactual state. Through a case study on the
greening of the Arctic and Boreal regions, we present evidence
demonstrating significant disparities between counterfactual and
conventional recovery time estimates. The well-documented greening of
the region serves as an external force, introducing non-stationary
dynamics that result in a counterfactual recovery time twice as long as
the conventional view. We advocate for embracing the counterfactual
definition of recovery, as it aligns more realistically with informed
decision-making.
Low-cost High-Speed Photogrammetry for Measuring Dynamic Flow Deposits
Authors: Chen Tzu-Yin Kasha , Hung Chi-Yao , Scheiber Michael , Hill Kimberly
Published: April 2024

We introduce a novel, cost-effective photogrammetry-based method
designed for measuring rapidly evolving three-dimensional surface
topography in particle-fluid flow experiments. This method offers
high-resolution results over a considerable surface area, enabling the
capture of dynamic flow events with temporal granularity limited only by
removable memory card capacity. Multiple WiFi-enabled security cameras,
meticulously calibrated with precision-measured reference points on
calibration boards, are employed in this methodology. External
synchronization, facilitated by strategically-positioned flash lamps,
allows calibration among cameras without additional precise tools.
Validating our method through an alluvial fan experiment showcases its
efficacy in tracking the growth and evolution of experimental debris
flows, particularly in capturing the dynamic evolution of debris flow
deposits on a growing alluvial fan. This example illustrates the
method’s ability to link local flow, evolution, and deposition to
multiple channel avulsion events, highlighting its success in capturing
distinct slope and height dependencies associated with these phenomena.
Overall, our method transcends conventional measurement approaches,
providing a significant advancement in capturing the intricacies of
rapidly evolving three-dimensional surface topography in particle-fluid
flow experiments. Its cost-effectiveness and robustness make it a
valuable tool for diverse, dynamic scenarios, presenting a promising
solution for experimental laboratory-scale landscape studies.