bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN MEDIA PEMBELAJARAN IPA BERBASIS POWTOON PADA POKOK BAHASAN KLASIFIKASI MATERI DAN PERUBAHANNYA DI TINGKAT SMP
Authors: Permatasari Annisaa Dwi Ayu , Fajar Dinar Maftukh
Published: May 2023

The development of Powtoon-based learning media on the subject of Classification of Materials and Its Changes at the junior high school level was carried out based on the problems that researchers found at SMP Negeri 1 Gending, Probolinggo, East Java, namely the decrease in students' enthusiasm for learning during COVID-19 outbreak, the lack of learning media that can be utilized, and the amount of material that must be mastered. This paper aims to describe the validity and students' responsesto the Powtoon based learning media on the subject of Classification of Materials and Its Changes at the junior high school level. The type of research carried out is research and development with a 4-D model (define, design, development and dissemination) where the dissemination stage is not implemented. The products that were successfully developed were 3 learning videos uploaded and distributed through Youtube.com. The results of the assessments of media experts, material experts, and product user teachers are included in the very valid category. The recapitulation of student responses gave positive results. Descriptions of student responses are mapped in the form of a Word Cloud with the words “interesting”, “excited”, “learning”, “understand” are words often mentioned. Students argue that this media has advantages from the animation aspect so that it grows attractiveness and motivation in learning.
Morbimortalidade Associada à Infeção por COVID-19 nos Idosos em Portugal: Comparação entre o período de Outono/Inverno de 2020 – 2021 e de 2021 – 2022
Authors: Alves Filipe , Oliveira-Dias Clara , Felgueiras Óscar , Duarte Raquel
Published: May 2023

N/a.
A fazenda modelo Sapucaia e o ensino agrícola no Espírito Santo da Primeira República
Authors: Conde Bruno Santos
Published: May 2023

O presente trabalho aborda a trajetória da fazenda modelo Sapucaia, no Espírito Santo, entre 1909 e 1912. Embora seu funcionamento tenha sido efêmero, o fato é que representa localmente a primeira ação concreta que visou à qualificação técnica de trabalhadores para a agricultura. Mais do que isso, tal fazenda se enquadra no movimento em defesa do ensino agrícola, crescente desde a segunda metade do século XIX em todo o Brasil. Este estudo se vale de publicações governamentais e do exame da imprensa do período, sempre em diálogo com a bibliografia pertinente. Ambiciona-se abordar as principais características dessa fazenda modelo, elucidando-se também aspectos como o contexto em que se enquadra, as concepções que lhe serviram de base, seu significado político, bem como suas limitações e adaptações enquanto local de instrução. Considerando que a instituição pretendeu oferecer um ensino pragmático, tendo como alvo o aprimoramento da atividade agrícola, coloca-se como tarefa examinar sua caracterização e funcionamento, de modo a compreender sua inserção na trajetória educacional capixaba.
O que queremos ensinar é mesmo clássico?
Authors: Santos Victor Ferreira Dias , Messeder Neto Hélio da Silva
Published: May 2023

O clássico é um dos critérios de seleção de conteúdos da pedagogia histórico-crítica. Apesar da sua relevância, vemos uma certa banalização no uso desse conceito, acompanhada de um discurso que, por vezes, faz parecer que é simples determinar o que seria o clássico em cada disciplina escolar. Para contribuir na construção de ferramentas para o processo de seleção de conteúdos, este texto tem como objetivo apresentar elementos que apontem um caminho investigativo para que cada área possa determinar com mais concretude quais seriam os clássicos. Como método, utilizamos uma análise conceitual-bibliográfica fundamentada no materialismo-histórico dialético de textos que abordam o conceito de clássico da pedagogia histórico-crítica. E, como síntese provisória, este trabalho apresenta três apontamentos para a investigação do conceito de clássico: a) conhecer a estrutura lógica do conhecimento a ser ensinado; b) entender o movimento histórico de seleção de conteúdos da disciplina específica; e c) investigar a história do desenvolvimento da ciência de referência. Por fim, apontamos a necessidade de avaliar coletivamente esses apontamentos, a fim de avançar na construção coletiva do entendimento do conceito de clássico.
Anti-Inflammatory Effect of Red Dragon Fruit (Hylocereus polyrhizus) Peel on Male White Rat
Authors: Yuna Pazri , Chiuman Linda , Ginting Chrismis Novalinda
Published: May 2023

Background: The side effects of synthetic anti-inflammatory drugs have become a known problem in medicine as well as in the general public. These side effects problems drive patients to seek alternatives to common anti-inflammatory drugs, especially natural alternatives. Phytochemicals such as flavonoids, alkaloids, and many different others have been identified as potential anti-inflammatory agents. Red dragon fruit (Hylocereus polyrhizus) is one source of such phytochemicals. Whilst the consumption of the flesh of red dragon fruit is very common, utilization of the peel is very rare and often becomes waste. Objective: This study aimed to explore the potential of red dragon fruit peel as an anti-inflammatory agent. Methods: This experimental study with a control group post-test-only design. This study involved in-vitro (protein denaturation inhibition using bovine serum albumin) and in-vivo (carrageenan-induced inflammation on an air-pouch model on 25 white rats) experiment. Results: This study showed that the red dragon fruit peel extract contains flavonoid, alkaloid, saponin, and tannin compounds. Administration of red dragon fruit peel extract suspension was found to be effective at inhibiting protein denaturation and reducing white blood count in the inflammation exudates, and the effectiveness is increasing along with the dose. Conclusion: It can be concluded that the red dragon fruit peel extract was effective as an anti-inflammatory agent, especially at a higher dose.
Red dragon (Hylocereus polyrhizus) fruit peel extract increased the motility and viability of spermatozoa of hypercholesterolemic rats (Rattus norvegicus)
Authors: Niken Meyliana Sari  , M. Gandul Atik Yuliani  , Eduardus Bimo Aksono Herupradoto  , Nanik Hidayatik  , Nurhusien Yimer  , Tatik Hernawati
Published: May 2023

This study aims to determine the effect of red dragon (Hylocereus polyrhizus) fruit peel extract (RDFPE) on spermatozoa motility and viability of hypercholesterolemic rats (Rattus norvegicus) as a model. Twenty male rats were randomly divided into negative control (NC), positive control (PC), treatment 1 (T1), treatment 2 (T2), and treatment 3 (T3) groups. All rats were given 2 mL of high cholesterol feed orally every day for 28 days. On day-15, all rats were measured for their blood cholesterol levels, followed by treatment for 14 days. Rats in the NC, PC, T1, T2, and T3 groups were treated with 1% Na-CMC, Simvastatin 10 mg/kg BW, and RDFPE of 500, 750, and 1000 mg/kg BW, respectively. On day-29, all rats were sacrificed to evaluate spermatozoa viability and motility. The results showed that spermatozoa viability and motility in the hypercholesterolemic rats (NC) group were the lowest (p <0.05) among the groups. Treatment of hypercholesterolemic rats with Simvastatin 10 mg/kg BW (PC) group showed higher (p <0.05) spermatozoa viability and motility compared to the NC group. RDFPE dose of 1000 mg/kg BW (T3 group) resulted in higher (p <0.05) spermatozoa viability and motility compared to other RDFPE doses (T1 and T2) and the control (NC) groups, and it was similar (p >0.05) compared with the Simvastatin treated (PC) group. It could be concluded that the administration of 1000 mg/kg BW ethanolic extract of red dragon fruit (Hylocereus polyrhizus) peel increased the viability and motility of spermatozoa of hypercholesterolemic rats (Rattus norvegicus) which were the same as the group of rats given Simvastatin 10 mg/kg BW.
Time estimation for mating peak and calving of Bali cattle in semi-arid area in Netemnanu village Kupang district
Authors: Marianus Yakobus Magul Datur  , Tarsisius Considus Thopianong  , Cynthia Dewi Gaina  , Nancy Diana Federika Katarina Foeh
Published: May 2023

Bali cattle have advantages in terms of adaptation and fertilization rates, but tend to have slow growth rate because the rearing system is still grazing so that livestock growth becomes uncontrollable. This study aims to determine the peak of mating and calving estimation of Bali cattle (Bos sondaicus) that did not experience reproductive disorders, aged 4-7 years, belonging to smallholder farmers. The cattle were reared in semi-arid area of Netemnanu village, South Amfoang district, Kupang regency, Nusa Tenggara Timur. The method used was interviews with farmers, diagnosis of pregnancy through rectal palpation and ultrasonography. The results showed that the pregnancy rate was 86.20% (50/58).  Based on pregnancy data, it was known that the peak of mating would occur in December 2021 and estimated calving would reach its peak in September 2022.
A Meta-Analysis of 80% Fraction of Inspired Oxygen on Surgical Site Infection in Patients Undergoing Surgery
Authors: Erisadana Rifaldy Nabiel , Tohari Achmad Ilham , Supranoto Yehuda Tri Nugroho , Utami Wiwien Sugih , Indreswari Laksmi
Published: May 2023

Background: WHO recommended the use of 80% FiO2 in patients undergoing general anesthesia with endotracheal intubation (ETI) to prevent surgical site infection (SSI). However, the ongoing debate regarding efficacy and safety raises because further trials have been published. We conducted a review based on recommendations in terms of SSI as the primary outcome and adverse events as the secondary outcome in both patients with or without ETI.

Method: A literature search was carried out by PubMed, ScienceDirect, and Google Scholar for RCTs in all-type surgical patients who administrated 80% FiO2 compared with 30–35% FiO2. Pooled relative risks with a 95% confidence interval were conducted for meta-analysis. Result: Based on 23 RCTs included in the analysis, there were no significant differences in terms of SSI (RR,0.85; 95%CI, 0.72 to 1.01; p=0.07), sepsis (RR,1.47; 95%CI, 0.78 to 2.76; p=0.23), postoperative hospitalization days (PHD) (RR,0.16; 95%CI, -0.67 to 0.98; p=0.71), ICU admission (RR,0.94; 95%CI, 0.78 to 1.13; p=0.50), reoperation required (RR,0.78; 95%CI, 0.30 to 2.06; p=0.62), and 30-days mortality (RR,1.18; 95%CI, 0.76 to 1.84; p=0.45). In contrast, even though the subgroup analysis showed association that PHD longer in high FiO2 group for colorectal surgery (RR,0.80; 95%CI, 0.24 to 1.35; p=0.005), the high FiO2 significantly reduced SSI and anastomotic leakage in abdominal surgery (RR,0.78; 95%CI, 0.62 to 0.99; p=0.04 and RR,0.55; 95%CI, 0.36 to 0.85; p=0.008).

Conclusion: This meta-analysis provides evidence that administration of 80% FiO2 even though association with longer of PHD in colorectal surgery, it is associated with a reduction in SSI and anastomotic leakage in patients who underwent abdominal surgery. It contrasts for sepsis, ICU admission, reoperation required, 30-day mortality, SSI, and PHD in all-type surgery. 
Análise da correlação entre a condição de pavimentos urbanos e elementos do sistema de drenagem
Authors: Diniz María Ingridy , Almeida de Melo Ricardo
Published: May 2023

A pesquisa em questão objetivou analisar a correlação entre o índice de condição dos pavimentos e a condição de dois elementos de drenagem superficial: bocas de lobo e sarjetas. O estudo foi realizado a partir da análise de 19 trechos, distribuídos pelo bairro de Tambaú, em João Pessoa-PB. O cálculo para a condição dos pavimentos foi realizado pelo método do PCI e a condição dos elementos de drenagem foi verificada por meio de análise subjetiva. Os resultados da pesquisa mostraram quando os elementos se enquadravam ou não nas condições ideais, e embora os elementos de drenagem sejam considerados no desempenho dos pavimentos, a avaliação estatística apresentou uma correlação fraca entre a condição dos pavimentos e os elementos de drenagem avaliados.
Influencia de variables experimentales en las propiedades mecánicas de los concretos reforzados con fibras de acero (SFRC) en experimentos de degradación por cloruros: revisión bibliográfica y análisis estadístico
Authors: Becerra Oslery , Meza Alejandro , Salinas Rogelio
Published: May 2023

La presente investigación tiene como objetivo evaluar el efecto de variables experimentales en el estudio de la degradación por cloruros de concretos reforzados con fibras de acero (SFRCs). La información fue recopilada de diferentes fuentes literarias para después ser tratada mediante el diseño experimental de Taguchi y análisis de regresión. Los resultados muestran que los factores más influyentes en la degradación de SFRCs degradados por cloruro son la carga durante la degradación y el ancho de fisura, factores que impactan estadísticamente sobre resistencia residual y la carga máxima a flexión. Sin embargo, otros como la relación agua/cemento, el volumen de fibras, la concentración de cloruros y el tiempo de degradación demostraron poca influencia sobre la respuesta mecánica de los SFRCs.
Estudo de painéis de concreto impermeabilizados com aditivo redutor de permeabilidade a base de silicato
Authors: Zomer Alves Fernando Espindola , De Paula Gurkewicz Rafael , Chemale Zancan Evelise , Jaramillo Nieves Leidy Johana , Pavei Antunes Elaine Guglielmi
Published: May 2023

Esta pesquisa estuda a capacidade de absorção de água em painéis de concreto e seu processo de autocicatrização, através da incorporação de aditivo ao concreto ou aplicação na superfície. Através de ensaios de permeabilidade, absorção de água por imersão e por capilaridade, após a cura úmida dos painéis, os painéis com aditivo cristalizante aplicado superficialmente apresentaram menor capacidade de absorção, seguido pelos sem aditivo e as com o aditivo incorporado ao concreto. Através da microscopia realizada nos painéis partidos ao meio, pôde-se observar que a cristalização dos painéis com aditivo superficial estavam mais avançadas em comparação aos com o aditivo incorporado. As fissuras induzidas não atingiram o total preenchimento de poros após a cura, em ambos os tipos de aplicação.
Nuevo modelo para el diseño completo de zapatas aisladas rectangulares tomando en cuenta que la superficie de contacto funciona parcialmente en compresión
Authors: Luévanos Rojas Arnulfo
Published: May 2023

Este documento muestra un nuevo modelo para diseño completo de zapatas aisladas rectangulares bajo flexión uniaxial y biaxial, tomando en cuenta que el área de la zapata en contacto con el suelo funciona parcialmente a compresión. La metodología se presenta por integración para obtener momentos, cortantes por flexión y penetración. Los ejemplos numéricos se presentan para el diseño de zapatas aisladas rectangulares bajo flexión uniaxial y biaxial, y se comparan con el modelo actual (área total funciona en compresión) en términos de volúmenes de concreto y acero. El modelo actual muestra mayores volúmenes de concreto y acero. Por lo tanto, el nuevo modelo es el más adecuado, ya que presenta mejor control de calidad en los recursos utilizados.
Gestión integral de la corrosión. Análisis documental
Authors: Donadio Michel , Capacho Juan , Santander Luis
Published: May 2023

El objetivo de este informe es hacer un análisis documental sobre las diferentes técnicas de mitigación de la corrosión disponibles en la actualidad, como los morteros de reparación, los inhibidores activos y pasivos de la corrosión, los revestimientos protectores y la protección catódica con corriente inducida o galvánica. Estas estructuras, construidas para durar mucho tiempo, están sometidas al envejecimiento por influencias de su entorno, como el agua, el dióxido de carbono atmosférico y otros elementos nocivos como los cloruros y la contaminación. El proceso de deterioro más común en las estructuras de concreto armado es la corrosión y la consiguiente dilatación de la armadura de acero, lo que provoca la fisuración y el desconchado del concreto.
IMPLEMENTASI BAYANI, IRFANI, BURHANI TERHADAP PENDIDIKAN KARAKTER SANTRI DALAM SISTEM PENDIDIKAN DI PESANTREN
Authors: Amrullah Muhammad Afif , B.K.P.S Alaika Muhammad , Fawaid Imam , Alfaruq Moch Ishaq
Published: May 2023

Regarding theiproblem of life, moral degradation is often heard in the body of the next generation of the nation. Starting from small children, adults, to the erderly. Today’s formal education tens to present learning materials based on intellectual intelligence, while in everyday life emotional intelligence and spiritual intelligence are needed. With the concept of marginal understanding, there will be a gap because someone's understanding is cognitively different. Especially now that it is supported by technological advances that are free to erode understanding of character. This then forms a character in a person because of his ability to internalize it. A person's character will experience ups and downs when theory is only used as a starting point in behavior.

            Through analysis Bayani, Irfani, and Burhani will describe how it is implemented in the education system. The method used is library research , in which the orientation is to examine books, manuscripts, and literature relevant to the object of research. The results of this study conclude that the education system in Islamic boarding schools is not only based on theory but habituation. The pesantren environment that brings them to study does not only apply knowledge through doctrination, but in actualization in their lives as santri. This can be seen through several phenomena that occur such as gangsters, fights between students, until narcotics are also found in young people. And this is rarely found for those who are in dormitories or from pesantren graduates.

Keywords: Bayani, Irfani, Burhani, Character, Islamic Boarding School
IMPLEMENTASI STANDAR PENGELOLAAN PENELITIAN: STUDI KASUS DI IAIN PALANGKA RAYA
Authors: Ajahari Ajahari , Puspita Puspita , Asmawati Asmawati , Misbah Misbah , Arifin Anwar , Hanafiyah Hanafiyah , Handayani Sri
Published: May 2023

This study aims to describe and analyze the implementation of research management standards which include planning, organizing, implementing, and controlling. The research approach used is descriptive qualitative with the case study method. The research subjects were Vice Rector 1, the Chair and Secretary of LPPM, the Head of the Research Center, and the Head of Planning and Finance of IAIN Palangka Raya. The determination of research subjects was carried out by purposive sampling with data collection techniques through observation, interviews, and documentation. The results of the research show that research management planning activities begin with the preparation of development master plans, strategic plans, and operational plans, preparation of research roadmaps, annual work programs, preparation of Terms of Reference and research budget plans, and the preparation of Research Guidelines. In implementing research management standards, there are 12 stages carried out, including dissemination of technical instructions, research registration, administrative selection, substance selection, determination of nominees, proposal seminars, determination of beneficiaries, preparation of work orders, disbursement of funds, conducting research, monitoring evaluation, review of research outputs, results seminars, and final reports. Efforts to control research activities are carried out with several strategies: making regulations and technical guidelines for research, managing registration and selection of proposals as well as meetings for determining nominees, preparing work orders, managing intermediate seminars, managing presentations of research results, making research logbooks, registering IPR research results, publishing articles research, seeking SPI involvement in research management activities, uploading research reports to Litapdimas, imposing sanctions, preparing research management reports, monitoring and evaluating research management.
ANALISA PENGARUH TRANSPARANSI, KREDIBILITAS, PENGETAHUAN, RELIGIUSITAS TERHADAP MOTIVASI MEMBAYAR ZAKAT DENGAN TEKNOLOGI DIGITAL SEBAGAI VARIABEL MODERATING DI LAZ NURUL HAYAT MEDAN
Authors: Munawar Rahmat , J. Nst Yenni Samri , Ridwan Muhammad
Published: May 2023

The motivation to pay zakat is to be willing to pay zakat by demanding incentives to pay it. Zakat is an obligation for Muslims to eradicate poverty and poverty in society and the ummah. The purpose of this study was to determine the effect of the variables of transparency, trust, knowledge, and religiosity on the motivation to pay zakat and the effect of the moderating variable of digital technology, as well as to determine the effect of the variables of transparency, trustworthiness, knowledge, and religiosity on motivation for the moderating variable of digital technology. on Zakat Payments at LAZ Nurul Hayat Medan. Significant effect on credibility, knowledge, religiosity, and motivation to pay zakat, up to 76.2%. Transparency, trustworthiness, knowledge, religiosity, and the level of moderation of digital technology have a huge impact on motivation to pay zakat up to 85.5%. The results of the significance test show that the variables of transparency, trust, knowledge, and religiosity have a significant and significant effect on the motivation to pay zakat. The moderating variable of digital technology can moderate religiosity about the motivation to pay zakat, but the moderating variable of digital technology is not able to moderate transparency, credibility, knowledge on motivation to pay zakat at LAZ Nurul Hayat Medan
STRATEGI DAKWAH TERHADAP NON-MUSLIM: STUDI ATAS PANDANGAN NAWĀWĪ AL-JAWĪDALAM TAFSĪR MARĀḤ LABĪD
Authors: Ghozali Mahbub , Aula Siti Khodijah Nurul
Published: May 2023

This study aims to determine strategy of da'wah to non-Muslims contained in Tafsīr Marāḥ Labīd by Nawawī al-Jāwī. Da'wah activities carried out against non-Muslims are always aimed at inviting them to convert Islam. This is contrary to the messages contained in the Qur'an and the values of religious freedom guaranteed by the state. This study uses a qualitative method with data analysis using content analysis. This study concludes that da'wah to non-Muslims in Nawawi's view is not in the form of an effort to invite them to Islam, but the delivery of a message to well behaved. The issue of faith, in Nawawi's view, is a guide that can only be given by God. In order for the message of da'wah to be conveyed, Nawawi emphasizes the da'wah method used that is not violent. This prohibition is absolute, except in the process the preacher experiences threats that can interfere with faith. However, Nawawī emphasized that if this happens and it is possible to avoid it, then a preacher is advised to avoid and not to resort to violence. In this context, Nawawī also prohibits acts of da'wah in the name of jihad in the form of violence.
REVITALISASI KURIKULUM LEMBAGA PENDIDIKAN AL WASHLIYAH DALAM MELAHIRKAN ULAMA
Authors: Napitupulu Dedi Sahputra
Published: May 2023

Ciri khas dari organisasi Islam Al Washliyah adalah lembaga pendidikannya yang berorientasi pada tradisi keulamaan. Penelitian ini bertujuan untuk menganalisis revitalisasi kurikulum lembaga pendidikan Al Washliyah dalam melahirkan ulama. Penelitian ini menggunakan metode kualitatif lapangan dengan menggunakan teknik observasi, wawancara dan studi dokumen. Hasil penelitian ini menunjukkan bahwa Al Washliyah secara khusus telah mendirikan lembaga Pendidikan Kader Ulama (PKU) yang dikelola oleh Fakultas Agama Islam UNIVA Medan. Kurikulum yang diterapkan adalah dengan tetap memelihara kurikulum pendidikan Al Washliyah dimasa lalu yang dominasi pelajaran agama ditambah dengan pelajaran umum sesuai dengan kurikulum pendidikan nasional yang berlaku. Sedangkan metode yang digunakan adalah dengan mengkombinasikan metode  moderen dan klasik (kitab kuning dan halaqah).
DEVELOPING AN ASSESSMENT MODEL FOR ISLAMIC MODERATION UNDERSTANDING OF PTKI STUDENTS: CONCEPTUAL, FUNCTIONAL, AND PROCEDURAL DIMENSIONS
Authors: Susmiyati Sri , Abdillah Muhamad Hasan , Zurqoni Zurqoni , Saugi Wildan
Published: May 2023

This study aimed to develop and test an assessment model for Islamic moderation understanding of Islamic higher education (PTKI) students. The assessment model was developed based on the dimensions of Islamic moderation understanding which includes the dimensions of conceptual understanding, functional understanding, and procedural understanding. The subjects were students of Sultan Aji Muhammad Idris State Islamic University Samarinda, Tarbiyah College Balikpapan, and Islamic College Sangatta, with a total of 224 students. The data collection instrument used was a test instrument. The data obtained were then analyzed using the Confirmatory Factor Analysis technique with the LISREL 8.51 program. The results of the data analysis show that the assessment model developed for Islamic Moderation understanding of PTKI students has very good validity and reliability. All item items have a factor loading value of > 0.3 and the assessment model has a Goodness of Fit Index (GFI) > 0.90. Thus, the assessment model for Islamic moderation understanding is very appropriate to be used as a reference for further research because theoretically, it is in accordance with empirical data obtained from subjects in the field.
Dinamika Kurikulum Pondok Pesantren Tahfiz Al-Qur′an di Kalimantan Selatan
Authors: Rasyidi Ahyar
Published: May 2023

The education system at the tahfiz Islamic boarding school is the same as the Islamic boarding school education system in general, namely there is a curriculum, learning methods, places of study and so on, it's just that there are differences from one hut to another so that it has its own uniqueness in observing it. This study aims to explain and analyze the Tahfiz Al-Qur'an Islamic Boarding School Curriculum in South Kalimantan. The method in this research is descriptive qualitative. There are several tahfiz Islamic boarding schools in South Kalimantan which are the research locations. The findings in this study are that the curriculum in each typology (model) of the Tahfiz Al-Qur'an pesantren has differences. Even within one typology there are some minor differences in the curriculum implemented by the Tahfiz Al-Qur'an pesantren. However, the similarity in the elements of implementing tahfiz Al-Qur'an education makes it found that differences in one typology or model of Islamic boarding school become very minor. In the first typology (model A), the tahfiz Al-Qur'an pesantren curriculum is formulated to support the main program, namely memorizing 30 chapters of the Al-Qur'an. While tahfiz Al-Qurʹan Islamic boarding schools are in model B, it is found that the Al-Qurʹan educational curriculum allocates more time for the tahfiz Al-Qurʹan program, in addition to implementing the existing formal curriculum from the ministry of religion at the Madrasah Tsanawiyah (MTs) and and Madrasah Aliyah (MA).
INCLUSIVE MADRASAH: CONCEPTS, APPROACHES, AND POLICIES
Authors: Anshari M.
Published: May 2023

One of the stigma and prejudice on people with disabilities arise in the educational setting, madrasah as Islamic educational institutions have contributed to exclusion and marginalization of muslim student with disabilities. Referring to the source from the education Management information System (EMIS) of The Kementerian Agama  of the Republic of Indonesia in 2021 its shows the number of Madrasah in Indonesia 83,648 madrasah, there are only several of madrasah that have implemented inclusive madrasah. This paper focuses on inclusive education in the context of Islamic educational institutions in madrasah, which is related to policies, concepts, and practices. Concepts and practices that have been carried out by a number of madrasah that provide inclusive education grow and develop bottom-up from practitioners and parents who have children with disabilities, and have been carried out by a number of madrasah that provide inclusive education grow and develop top down The Kementerian Agama of the Republic of Indonesia appointed several madrasas as piloting projects for inclusive madrasah. This article attempts to review various studies regarding inclusive madrasah in Indonesia as the concepts, approaches and policies.
Preserving the Authenticity of the Quranic Recitation: The Importance of Sanad Lineage at Tahfiz Boarding School in South Kalimantan
Authors: Rasyidi Ahyar
Published: May 2023

This study aims to explain and analyze the reading Sanad of tahfiz Al-Qur'an Islamic Boarding Schools in South Kalimantan. This study uses a phenomenological approach as proposed by Alfred Schutz and Peter L Berger. The goal of the phenomenological approach is to understand everyone's beliefs, including the most controversial interpretations within the tradition. Phenomenology does not attempt to analyze or explain an event, but the basic concept of phenomenology is meaning. Based on the research findings, that in South Kalimantan, in general, the tahfiz Al-Qur'an boarding school received a channel for reading through the Al-Qur'an education they had previously attended, or the boarding school where they became students. Although there are some ustaz who are not willing to reveal the path of their reading chain, and some others do not yet have a reading chain. The dynamics of the sanad and the methods used in the tahfiz Al-Qur'an Islamic boarding school in South Kalimantan, are not much different from other regions. The talaqqi or encounter method, is the isnad line that is often used in every tahfiz Al-Qur'an boarding school in South Kalimantan, the genealogy of the Al-Qur'an reading owned by the teachers, was obtained from their previous kiai, that is, from the kiai at the Islamic boarding school where they recited and memorized the Qur'an previously, then passed it down by talaqqi to their students, of course, who have met the agreed conditions and become the rules for giving sanad at each tahfiz Al-Qur'an Islamic boarding school.
Reviving The Legacy The Role of Islamic Education in Patani, South Thailand
Authors: Salaeh Fatonah
Published: May 2023

Patani is a region located in the southern part of Thailand, bordering Malaysia. It has a rich and diverse cultural heritage that is deeply rooted in Islam. For centuries, the people of Patani have maintained a unique identity that reflects their Islamic faith, traditions, and way of life. One of the key pillars of this identity is the education system, which plays a vital role in preserving and transmitting the values and teachings of Islam to the younger generation. The purpose of this research is to explore the current state of Islamic education in Patani, its challenges, and its role in preserving the cultural and spiritual heritage of the region. The study aims to provide insights into the efforts being made to revive the legacy of Islamic education in Patani and the impact of these efforts on the community. This research utilizes a qualitative research method, specifically, a case study approach. Data were collected through interviews with key stakeholders in the region, including religious scholars, educators, and community leaders. Secondary sources, such as academic articles and reports, were also consulted to provide a broader context for the study. The findings of this research suggest that the traditional Islamic education system in Patani is facing numerous challenges, including the impact of modernization and globalization, the ongoing conflicts in the region, and the limited access to resources and funding. However, there are also promising developments, such as the establishment of new Islamic schools that incorporate modern subjects into their curriculum and the use of technology to enhance the learning experience. The study also highlights the important role of Islamic education in promoting peace, harmony, and understanding in the region. Overall, this research contributes to a deeper understanding of the importance of Islamic education in Patani and the challenges and opportunities facing the system. The study provides insights into the efforts being made to revive the legacy of Islamic education in the region and their potential impact on the community.
Practical Teaching and Learning Methods in Malaysian Islamic Education
Authors: Rozali Mohd Hilmi , Jasmi Kamarul Azmi , Nazim Muhamad Amirul Amin Mohamad , Sahran Rasidah
Published: May 2023

The need for the right method is important in the practical teaching and learning (T&L) of Islamic education to create a positive impact in students and produce an ideal T&L. The T&L method used must be compatible with the measurement of the students so that the objectives are planned to produce maximum impact. Therefore, this article explores the T&L method that is often used by Islamic education teachers (IET) in implementing effective Islamic Education practices. The research methodology of this writing uses a qualitative study with a case study design conducted in seven secondary schools. Purposive and snowball sampling methods were used to select study participants and informants, namely seven study participants and 21 informants.Data collection through three instruments, namely interviews as core data triangulated with observation data and document analysis as supporting data.Verbatim data from interviews, observations, and analysis documents were analyzed in Nvivo20 software, finally becoming a model of Islamic education practical T&L method (MK-PAPI) after being validated by experts. The findings show that there are 11 practical T&L methods that are often practiced by IET, namely demonstrations; repetition; discussion; problem solving; simultaneously; presentation; questionnaire; memorization; collaboration; explanation or lecture; and direct application.
Results on a Pre-T_2 Space and Pre-Stability
Authors: Jasim Anmar Hashim
Published: May 2023

This paper contains an equivalent statements of a pre-  space, where  are considered subsets of with the product topology. An equivalence relation between the preclosed set  and a pre-  space, and a relation between a pre-  space and the preclosed set  with some conditions on a function  are found. In addition, we have proved that the graph  of  is preclosed in if  is a pre-  space, where the equivalence relation  on  is open.

     On the other hand, we introduce the definition of a pre-stable ( pre-stable) set by depending on the concept of a pre-neighborhood, where we get that every stable set is pre-stable. Moreover, we obtain that a pre-stable ( pre-stable) set is positively invariant (invariant), and we add a condition on this set to prove the converse. Finally, a relationship between, (i) a pre-stable ( pre-stable) set and its component (ii) a pre- space and a (positively critical point) critical point, are gotten.
Prevalence and Risk Factors of Bovine Tuberculosis in Cattle in Selected Districts of Fafan Pastoral Settings, Eastern Ethiopia
Authors: Hussein Hassan Abdi , Musse Abdi Hussein
Published: May 2023

Cross-sectional study was conducted from October 2021 to August 2022, to investigate the prevalence and associated risk factors of bovine tuberculosis in cattle in selected districts of Fafan zone. The prevalence was 11.24% (95% CI, 8.61-14.35) and 43.3% (95% CI, 33.27-53.75) at individual and herd level respectively. There were statistically significant differences in proportions of positive reactor animals among body condition score (χ2 = 47.9, P = 0.000), Age (χ2 =6.0937, P=0.048), Seasonal migration (χ2=4.320, P=0.038), parity number (χ2 = 10.62, P = 0.005), reproductive status (χ2 = 4.36, P = 0.037). Animals with poor body condition scores had a significantly higher likelihood of testing positive, with their odds being 11.4 times greater (COR=11.408, CI=3.43-37.94, P<0.001). Conversely, a good body condition score was linked to a decreased risk of infection. In multivariate logistic regression poor body condition score remained significantly associated with the odds of reacting positive for tuberculosis (AOR=0.137, CI=0.053-0.356, P<0.001). Similarly, the analysis showed that seasonal migration (AOR=2.935, CI=1.152-7.481, P=0.024), and parity number (AOR=11.91, CI=1.828-77.62, P=0.010), were significant predictors of bovine tuberculosis infection in cattle. According to questionnaire, 14.2% (17 of 120) and 13.3% (16 of 120) of the respondents were knowledgeable about bovine tuberculosis and its transmission from animal to human and vice versa, respectively. The general judgment of herders' understanding of bovine tuberculosis transmission methods to humans was very low. Study findings show high prevalence of bovine tuberculosis in the study area, emphasizing the need for an effective control strategy.
The role of human endometrial stem cells application in endometrial-factor induced infertility
Authors: Bausyte Raminta , Vaigauskaite Brigita , Borutinskaite Veronika , Valatkaite Elvina , Besusparis Justinas , Valkiuniene Ruta Barbora , Kazenaite Edita , Ramasauskaite Diana , Navakauskiene Ruta
Published: May 2023

Background.
Endometrial-factor induced infertility remains one of the most significant pathology among all fertility disorders. Stem cell-based therapy is considered to be the next-generation approach. However, at this point there are still issues about successfully retrieving human endometrium derived stem cells (hEnSCs). Moreover, we also need to establish a better understanding of the effect of hEnSCs on the endometrial recovery and the clinical outcome.
Methods.
Endometrium samples were collected from females undergoing assisted reproductive technology (ART) procedure due to couple infertility. These samples were obtained using an endometrium scratching. The hEnSCs were isolated from endometrium samples and characterized with flow cytometry analysis. Groups of endometrium injured female mice were established by the mechanical injury to uterine horns and the intraperitoneal chemotherapy. The hEnSCs suspension was injected to some of the studied female mice at approved time intervals. Morphological changes of mice uterine horns were evaluated after Masson‘s trichrome original staining and hematoxylin and eosin (H&E) staining. The fertility assessment of mice was performed by counting formed embryos. The expression of fibrosis related genes (Col1a1, Col3a1, Acta2 and CD44) was evaluated by the reverse transcription – quantitative polymerase chain reaction (RT-qPCR).
Results.
Endometrium scratching is an effective procedure for stem cells collection from human endometrium. Isolated hEnSCs met the criteria for defining mesenchymal stem cells (MSCs). Moreover, hEnSCs-based therapy had a demonstrably positive effect on the repair of damaged uterine horns layers, including a reduction of fibrosis, intensity of inflammatory cells such as lymphocytes and polymorphonuclear cells (PMNs) and the number of apoptotic bodies. The injured female mice had higher fertility after hEnSCs-based therapy in comparison to the untreated mice models. Gene expression was also reflected in morphology changes and outcomes of conception.
Conclusions.
hEnSCs demonstrated a positive impact on endometrium restoration and outcomes of endometrial-factor induced infertility. Further exploration is required in order to continue exploring the multifactorial associations between stem cell therapy, gene expression, endometrial changes and reproductive health, so we can identify individually effective and safe treatment strategies for endometrial-factor induced infertility, which is caused by mechanical effect or chemotherapy, in daily clinical practise.
Structure of histone deacetylase complex Rpd3S bound to nucleosome
Authors: Wang Haibo , Cui Hengjun
Published: May 2023

Histone modifications are involved in the regulation of chromatin-based processes, including transcription, DNA replication and repair1–5. Among them, histone acetylation and deacetylation are usually correlated with transcription activation and repression, respectively6. The Set2-Rpd3S pathway maintains hypoacetylation states of actively transcribed chromatin regions to suppress cryptic transcription initiation7–9. During this process, the histone deacetylase (HDAC) complex Rpd3S is recruited to nucleosomes which are methylated at lysine 36 residue of histone H3 (H3K36me) by histone methyltransferase Set27,9. However, how the five unique subunits of Rpd3S are assembled and coordinated to recognize nucleosomal substrates and exert its deacetylation function remains unclear. Here, we report the cryo-electron microscopy (cryo-EM) structure of Saccharomyces cerevisiae Rpd3S deacetylase bound to H3K36me3-modified nucleosome at 3.1 Å resolution. It reveals that Sin3 and Rco1 subunits orchestrate the assembly of the complex and mediate its contact with nucleosome at multiple sites. In addition, the chromodomain (CHD) of Eaf3 subunit recognizes the H3K36me3 marker and contacts both nucleosomal and linker DNA. The structure not only unravels the architecture of the Rpd3S complex, but also sheds light on the structural basis of its nucleosome targeting and function.
Multiple Conceptual Model Approach for Assessing Groundwater Resources Sustainability Under Multiple Stresses
Authors: Yidana Sandow Mark , Dzikunoo Elikplim , Adams Richard Mejida , Tetteh Jacob Doku
Published: May 2023

Six transient numerical groundwater flow models have been developed and calibrated based on six equally plausible conceptual models of the hydrogeological framework of Akyem and surrounding areas in southern Ghana, for the purpose of assessing the impacts of multiple stresses on groundwater resources sustainability in the area. The six conceptual models were developed to account for possible uncertainties in model predictions arising from uncertainties in the model structure and differ in terms of the characterization of domain boundaries and vertical stratification. The domain was conceptualized based on available data monitored over a 48-month period, from 41 boreholes in the area. Each of the calibrated numerical models was used to assess the impacts of enhanced groundwater abstraction attending population growth, and natural stresses accruing from climate change in the region. The forecasts of the six models provide a range of possible impacts of the various stresses on the system. This research finds that groundwater resources in the terrain are vulnerable to the impacts of climate change and enhanced abstractions to meet growing domestic water resources requirements. The business-as-usual scenario whereby groundwater abstraction rates continue at the current rate of population growth, with the same levels of groundwater recharge is not sustainable. This is likely to be worsened by reduced groundwater recharge resulting from enhanced anthropogenic activities and climate change. The six versions of the numerical model over the domain, although provide different results, all agree on the impacts of prevailing and future stresses on the system.
Noise cancellation with LMS, NLMS and RLS filtering algorithms to improve the fault detection of an industrial measurement system
Authors: Lampl Tanja , Hadi Abdul , Qadir Abdul , Andeme Juan Manuel Nzamio Mba
Published: May 2023

Adaptive noise cancellation is the process of filtering or estimating a desirable signal from a noise-corrupted observation. This method requires adaptive filters due to the unknown or varying input signal and noise properties. This article provides an overview of the three commonly used adaptive filtering algorithms, namely the Least Mean Square LMS, the Normalized Least Mean Square NLMS and the Recursive Least Square RLS algorithm. These filtering algorithms are investigated to cancel out the noise effect from noise-corrupted data when no reference signal is available. The algorithms are used to elaborate on a specific problem of industrial measurement systems for fault detection, which is corrupted by the thermal noise in sensors. A comparison is shown among these three adaptive algorithms that perform the best desired estimation and noise-canceling effect under the white noise environment. Three comparison criteria are used to evaluate the performance of these algorithms: the error performance, the rate of convergence and the signal-to-noise ratio (SNR). The simulation results demonstrate that the NLMS algorithm shows an excellent noise-cancelling effect in terms of a lower error performance and a higher SNR at the same convergence speed compared to the LMS and RLS algorithm, which improves the fault detection performance of the industrial measurement system.
Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Authors: Reissland Michaela , Hartmann Oliver , Tauch Saskia , Prieto-Garcia Cristian , Schulte Clemens , Solvie Daniel , Loebbert Sinah , Jacomin Anne-Claire , Pesic Marina , Bugter Jeroen , Schülein-Völk Christina , Fuss Carmina , Pahor Nikolett , Ade Carsten , Buck Viktoria , Potente Michael , Li Vivian , Beliu Gerti , Wiegering Armin , Bitman-Lotan Eliya , Grossmann Tom , Rosenfeldt Mathias , Eilers Martin , Maric Hans , Maurice Madelon , Greten Florian , Dikic Ivan , Oryan Amir , Gallant Peter , Diefenbacher Markus
Published: May 2023

The contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin stability, potentiating WNT signalling and cancer stem cells and CRC. Mechanistically, interaction and in vitro binding studies, together with computational modelling, revealed that USP10 binding to β-Catenin is mediated via the unstructured N-terminus of USP10 and requires the absence of full-length APC. Reduction of USP10 induces the expression of differentiation genes and opposes the APC-truncated phenotype in an intestinal hyperplasia model. Notably, loss of USP10 in CRISPR engineered intestinal organoids opposed the super competitor-signalling and reduced tumorigenic properties of APC-mutated CRC. Taken together, our findings reveal USP10s role in CRC cell identity, stemness and tumour growth by stabilising β-Catenin, leading to aberrant WNT signalling, and implicate USP10 as a cancer specific therapeutic vulnerability in Apc truncated CRC.
Physics-Informed Neural Networks for Hurricane Reconstruction and Data Assimilation
Authors: Eusebi Ryan , Vecchi Gabriel , Lai Ching-Yao , Tong Mingjing
Published: May 2023

Tropical cyclones (TCs) are responsible for large-scale loss of life and property, and billions of dollars worth of damage annually. Forecasting is typically accomplished through the use of dynamical models which directly integrate the governing equations of motion. These forecasts, and especially intensity forecasts, rely on accurate initial conditions obtained by assimilating real-time observational data. However, current methods used to generate these initial conditions are computationally expensive and limited, and TC intensity forecasts have much room for improvement. Here, we show that a Physics-Informed Neural Network can provide a promising alternative for data assimilation for TC initial conditions. Using synthetic training data sparsely sampled from hurricanes simulated in a forecast model, a PINN is able to accurately reconstruct full 2- and 3-dimensional wind and pressure fields of a TC. We also demonstrate how a set of sparse, real-time observations, can be used to accurately reconstruct Hurricane Ida. Our results demonstrate how recent advances in computational capabilities and deep learning can be applied to TC data assimilation, offering an accurate and efficient complement to existing data assimilation methods.