bluuebunny/crossref_metadata_2025 huggingface dataset:
ENHANCING GEOMATICS ENGINEERING EDUCATION THROUGH VIRTUAL REALITY
Authors:   Sultan Qaboos University, Muscat, El-Diasty Mohammed
Published: January 2025

This paper investigates the application of the virtual reality (VR) technology
in geomatics engineering education and its possibilities of changing the
learning landscape in this discipline. Several challenges can be attributed
to fields like Surveying, Geographic Information System and Remote
Sensing which inclusive comes under Geomatics Engineering. This
technology programming provides students with rich experiences through
immersive and interactive features which allow learner to practice
technical competencies and solve problems through field exposure. Today,
it is entirely possible to develop new forms of courses by using the VR
technology: adapting the course modules, organizing group learning,
providing access to industry instruments and applications. In addition, the
introduction of VR works well in improving delivery more specifically on
accessibility constraint in the areas of geographic location, cost as well as
disability. This paper explores the possibility of VR integration for
geomatics engineering education, analyses trend and discusses direction
for added improvement and research within the field.
APPLYING SECOND LANGUAGE ACQUISITION (SLA) STRATEGIES TO PROGRAMMING EDUCATION: A COMPARATIVE ANALYSIS OF LEARNING APPROACHES IN EARLY JAPANESE CURRICULUM
Authors:   Shonan Institute of Technology, Kanagawa, Japan, Umezawa Katsuyuki
Published: January 2025

In recent years, the “government curriculum guidelines” have been
revised in Japan to emphasize the early introduction of English and
programming education. Foreign language activities were included in
elementary school curriculum as for English education, and full-fledged
information education began in elementary and secondary education as for
programming education. There are two specific methods, i.e., “learning
concepts themselves” and “learning from examples,” for learning concepts
in programming learning. However, no unified view exists as to which of
these two methods should be started in the introductory stage of learning.
Many research have been conducted on programming learning strategies.
The authors thought that programming languages and English can be
regarded as common terms of “second language,” which is a language
other than their mother tongue. Moreover, the authors thought that the
second language acquisition (SLA) approach, which has been extensively
studied in programming language learning, could be applied. In this paper,
the authors classify the subjects they are in charge of using the level
classification method of programming language learning defined in
previous research. This categorization indicates that the author's course
covers all comprehension levels defined in the second language acquisition
project in blended learning (SLA-aBLe) project (from minimal
comprehension to advanced fluency).
Influence of Volume of Online Customers’ Reviews on Hotel Reservations in Tanzania
Authors: Georgina Gustav , Komba Silverius C. , Mbogo Crispin
Published: January 2025

The study aims to explore the Influence of volume of Online customers´ Reviews on Hotel Reservations in Tanzania. The study specifically assessed the contribution of the number of reviews, comprehensiveness, and hotel rating and their contribution to hotel reservations at Mediterraneo Hotel in Dar es Salaam. This study employed descriptive case study design while primary and published secondary data from the internet were used for data collection. The findings showed that high ratings and the number of hotel reviews on travel applications influenced customers to choose the hotel. The findings revealed that, hotel customers make reservations after checking reviews and hotel ratings on social media pages or travel applications, and complete, detailed, and timely Messages motivated customers to choose the Hotel. The study concluded that, the volume of customer reviews (number of reviews, comprehensiveness, and rating) is significant on Hotel reservations and increase revenue. This study recommends that, emerging of information sharing platforms and network communication should be used effectively by the hotel sector and Mediterraneo in particular, to disseminate corporate information, collect and organize consumer information from travel applications, websites, and social media platforms at low cost, and help them to manage customer relationships and provide competitive services.
Advancing Workforce Sustainability: Policy Reforms for Flexible Working Arrangements in Achieving National SDGs
Authors: Amirul Sharifah Rahama , Shaari Sharija Che , Jones Stephen
Published: January 2025

Workforce sustainability is a cornerstone of economic growth and societal well-being. One game-changing policy instrument for increasing workplace diversity, inclusion, and adaptation is the rise of flexible working `arrangements (FWAs) in Malaysia. As Malaysia strives to align with the United Nations Sustainable Development Goals (SDGs), particularly those focusing on economic growth, gender equality, and well-being. This paper critically analyses four main areas related to FWAs in Malaysia. First, it discusses the rationale of FWAs in supporting the three main SDG goals, which are to improve good health and well-being, gender equality, decent work and economic growth. Second, the paper reviews the contemporary FWA policy in Malaysia. Thirdly, the paper discusses the development of FWA’s Regulations in Malaysia. Based on these three main critical reviews, we argue that a greater emphasis should be placed on advancing Workforce Sustainability by reforming FWAs policies in achieving National SDGs. We developed an analytical FWAs policy framework that can be used in negotiation or decision-making to lead the development of a more thorough set of policies for managing FWAs. These reforms are crucial for developing a stronger and coherent labour market that can support national and global development goals.
The Dynamism of Classical Nusantara Historiography
Authors: Primaditya Krisnanda Theo
Published: January 2025

Indonesian historiography has entered a new era. Narratives of the past, set within the spatial boundaries of Indonesia, have undergone significant transformations over time. Temporal reconstructions extend back to ancient or classical periods, eras marked by the rise and fall of kingdoms across the archipelago. This study critically examines how well classical Nusantara historiography is understood and appreciated by contemporary Indonesian society. The methodology employed in this article is literature review, drawing on historical sources to explore interpretations and narratives of the classical Nusantara era that can be reconstructed and understood by present-day readers. It is essential for Indonesians to develop a more critical understanding of classical historiography, which relies heavily on scarce sources and the interpretive creativity of its authors. Today, studies on the classical period with various themes are flourishing like mushrooms in the rainy season. This dynamic historical writing represents a rich intellectual heritage. The diversity of perspectives on the classical era opens a fascinating space for discussion, as this exotic land straddling the equator has cultivated a society with a romantic spirit, evoking a vibrant and illustrious image of the past.
Exploring Constraints Faced by Women’s Self-Help Groups in Lupane District: Proposing Viable Solutions
Authors: Tshuma Nothando , Banwa Faith , Setoboli Tsepeso , Sibanda Emmanuel , Mpofu Sindiso
Published: January 2025

Gender equality and women’s empowerment have become increasingly significant in Zimbabwe, aligning with the Sustainable Development Goals (SDGs). In rural Matabeleland communities, Self-Help Groups (SHGs) play a crucial role in empowering women. However, despite their potential, SHGs often face high failure rates. This study aimed to investigate the challenges faced by SHGs and propose practical solutions. A qualitative research design was employed, using purposive sampling to select 56 respondents from the 28 wards in Lupane District. Data were collected through in-depth interviews and focus group discussions. The findings revealed several challenges: economic constraints related to product demand and limited access to funds, personal challenges such as confidence issues and time management, and social constraints, including gender stereotyping from family and community. The study concluded that the major challenges facing SHGs are economic, personal, and socio-psychological. The study recommends implementing financial literacy programs focusing on budget management, saving strategies, and investment planning. Additionally, with NGO support, SHGs should conduct workshops on market linkages, personal development, self-esteem, and skills enhancement. Addressing gender stereotyping through awareness programs is also crucial. Future research could examine the impact of SHGs on improving livelihoods and their contribution to economic growth.
The Roles of Multicultural Education: A Research Article on Promoting Inclusivity, Cultural Awareness, and Global Preparedness
Authors: Semila Catherine E. , Señal Noreenbeth Paula L. , Baculio Janine Kate V.
Published: January 2025

Multicultural education is an educational approach aimed at fostering equity and inclusivity among students from diverse cultural backgrounds. Its primary goals include promoting inclusivity, ensuring that all students feel valued and respected, and enhancing cultural awareness to develop empathy and interpersonal skills. This approach prepares students for a globalized society by equipping them with essential competencies such as critical thinking and intercultural communication. Additionally, multicultural education challenges biases and stereotypes, encouraging students to critically examine societal norms and advocate for social justice. By implementing these strategies, multicultural education not only creates a conducive learning environment but also empowers students to thrive in an increasingly interconnected world.
Assessing Knowledge and Compliance of Nurses with Infection Control Protocols
Authors: Idanan Ahdel D. , Ubalde Irys A. , Tejerero Rosalin Rosette Z. , Pampanga Erma B.
Published: January 2025

Healthcare-associated infections (HAIs) remain a serious threat to patient safety worldwide, with a marked impact in the Philippines. Nurses, as frontline healthcare providers, play a key role in infection control, and their compliance with infection control protocols is essential in reducing HAIs. This study evaluated the knowledge and compliance levels of registered nurses in hospitals in Catanduanes, aiming to identify factors that influence their adherence to these protocols. Employing a cross-sectional correlational design, data were gathered from 58 nurses using WHO’s Compliance with Standard Precautions Scale (CSPS) and a Knowledge Questionnaire (KQ) on HAIs. The mean knowledge score was 11.87, indicating a generally “good” understanding of infection control measures. Universal knowledge was demonstrated in hand hygiene, with 100% correct responses for statements like “Washing hands with soap or an alcohol-based antiseptic reduces the risk of pathogen transmission.” In contrast, lower scores appeared for specific practices, such as “Rubbing hands until dry when using alcohol-based antiseptics” (41.67%) and “Disinfecting all spills with alcohol” (58.33%). Compliance averaged 70.92%, classified as moderate, with high adherence in areas such as hand hygiene (96.67%) and glove use (93.33%), but lower rates in PPE reuse (36.67%) and waste management (40.00%). A significant positive correlation (r = 0.346, p = 0.007) was found between knowledge and compliance, indicating that enhanced knowledge can improve adherence. In line with these findings, targeted training programs and adequate resource provision, particularly PPE, are recommended. Moreover, policy initiatives may focus on enhancing infection control infrastructure in regional hospitals. Future research may examine additional factors influencing compliance and extend similar studies to other regions to enhance infection control nationwide.
Root Cause Analysis of Adverse Outcomes in the Obstetrics & Gynaecology: A Prospective Study at a Tertiary Care Centre
Authors: Narayan Brijesh , Mendiratta Pushkar
Published: January 2025

Background
: Adverse events are an unwanted outcome in the routine course of patient management, with an adverse event in Obstetrics assuming even greater importance because of the extended implications for the newborn. There is limited data available on the adverse event emanating from Obstetrics and Gynaecology care in Indian population. Materials and
Methods: This prospective observational study which included all the consecutive inpatients admitted with the department of Obstetrics and Gynaecology over a period of 15 months at a tertiary care centre. Incidence of adverse events were noted. Root cause analysis of the events was done and contributory factors brought out were addressed. Results: The incidence of the adverse events in our study was 2.57 % (n=90) in a total of 3503 consecutive inpatients. The most common adverse event noted in our study was surgical site infection followed by birth asphyxia. The average duration of detection of adverse event was 8.5 days, with adverse event detected in 73% patients during admission. Out of these, 98.48% had a prolonged hospital stay which averaged 5.5 days. 58% of the adverse events were grade 3 in severity while 91.1% were deemed preventable. Conclusion: Adverse events carry a giant burden with them, but their incidence can definitely be cut down by adhering to institutional protocols, checklists, increased awareness and involvement at multiple levels of hierarchy.
Implementasi Perencanaan Kurikulum Sesuai Dengan Perkembangan Zaman (Studi Kasus di Madrasah Aliyah Negeri 3 Aceh Utara)
Authors: Wahyuni Suci
Published: January 2025

This research aims to find out how the implementation of curriculum planning, whether it is in accordance with the development of the times applied in Madrasah Aliah Negeri 3 North Aceh and what are the factors that hinder the curriculum planning. This research is a field study with a descriptive qualitative approach. Data sources consist of primary data and secondary data. The data collection technique uses observation, interviews and documentation. Data analysis is carried out by reducing data, presenting data and drawing conclusions from the data that has been collected. Meanwhile, to ensure the validity of the data, triangulation techniques with theory are used. The results of this study show that: (1) The planning of the MAN 3 North Aceh curriculum has been running in a structured manner such as the preparation of prota, prosem, time allocation program, syllabus, lesson plan, KKM and others, but it is still necessary to align the plans that have been made so that everything can be carried out as planned at the planning meeting which is held routinely at the beginning of the school year. (2) Obstacles that arise in the curriculum planning process at MAN 3 North Aceh are caused by human resources (HR) in madrasas. Lack of awareness of each individual's responsibility, cognitive ability, and professionalism of human resources are the main factors in the emergence of these obstacles. (3) As an effort to overcome the obstacles that arise, improving the quality of human resources is the main solution in the success of madrasah curriculum planning activities. Good madrasah resources will result in the achievement of educational goals optimally.
Cierre de fistula esófago-yeyunal post operatoria con clips endoscópicos de titanio y over-the-scope clip: reporte de caso
Authors: Arango Molano Lázaro , Sánchez Gil Andrés , Núñez Rojas Gian , Solarte Pineda Herney , Salazar Ochoa Santiago
Published: January 2025

Las fístulas de las anastomosis esófago-yeyunales postquirúrgicas pueden llegar a ser mortales. En la actualidad existe un amplio arsenal de medidas terapéuticas que van desde el manejo conservador, la terapia endoscópica, hasta la cirugía de revisión. El manejo endoscópico se ha posicionado por encima de las demás estrategias debido a la mínima invasión, lo que mejora la sobrevida y disminuye la mortalidad. El tratamiento endoscópico de las fístulas esófago-yeyunales puede ser variado con numerosas técnicas descritas para lograr el cierre de estas. Dentro de estas técnicas destacan la colocación de stents autoexpandibles recubiertos o parcialmente cubiertos, el uso de clips metálicos, solos o ayudados por la técnica del loop, el uso de la terapia de presión subatmosférica cerrada endoscópica (e-VAC) y, más recientemente, el uso de sutura endoscópica. En nuestro servicio usamos las técnicas nombradas de acuerdo a las características de la fístula. En el caso presentado se decidió, en el momento mismo de la endoscopia, el uso de clips con la ayuda de un Cap para facilitar la técnica y en el ángulo terminal de cierre, ante el tejido redundante de difícil aproximación, optamos por poner un clip tipo Padlock®; con esto se logró el cierre de la lesión en pocos días y una excelente evolución del paciente.
Evaluación del uso de corticoides como un marcador de atención de calidad en el manejo de la enfermedad Inflamatoria Intestinal
Authors: Quera Rodrigo , Núñez F. Paulina , Flores Lilian
Published: January 2025

Introducción: A pesar de los avances en las estrategias terapéuticas, los corticoesteroides siguen desempeñando un papel en inducir la remisión en la enfermedad inflamatoria intestinal (EII). Desafortunadamente, estos medicamentos suelen ser mal utilizados. Objetivos: Evaluar la dosis y duración de la terapia con corticoesteroides y el cambio posterior en el tratamiento en los pacientes con EII. Materiales y métodos: Estudio descriptivo, retrospectivo y observacional en pacientes con EII en seguimiento en el Programa de Enfermedad Inflamatoria Intestinal de la Clínica Universidad de los Andes desde enero de 2021 hasta agosto de 2022. Resultados: Se incluyeron 432 pacientes con EII, de los cuales el 63% eran mujeres, con una mediana de edad de 42 años (rango de 14 a 94 años), y el 66% tenía colitis ulcerosa (CU). El sesenta y seis por ciento de los pacientes habían recibido corticoides durante el curso de su enfermedad (entre 1 y 9 veces) con una mediana de duración de 12 semanas (rango de 2 a 48 semanas), siendo la prednisona el corticoide más utilizado (53%). El setenta y siete por ciento de los pacientes habían recibido tratamiento durante más de 3 meses o en dosis supra-terapéuticas (prednisona >60 mg/día). Hubo un cambio en el tratamiento de la EII posterior al uso de corticoides en el 28% de los pacientes frente al 90% después del ingreso al programa (p<0,001, IC95%: 1,83-2,49). Durante el seguimiento del Programa de EII, el 10% de los pacientes recibió corticoides (71% prednisona, 29% budesonida) sin variaciones según el tipo de EII, género, edad o tratamiento. Ningún paciente recibió corticoides durante más de 3 meses o en dosis supra-terapéuticas en nuestro Programa de EII. Conclusión: Este estudio enfatiza la importancia de evaluar el uso de corticoides como un marcador de calidad de atención en la EII. El manejo de estos pacientes a través de un programa especializado podría mitigar el uso excesivo de estos fármacos.
Helicobacter pylori and its role in the pathogenesis of follicular gastritis: an overview
Authors: Carlosama-Rosero Yeison , Latorre Gonzalo , Riquelme Arnoldo , Portillo-Miño José Darío
Published: January 2025

The role of Helicobacter pylori in the pathogenesis of peptic ulcers and gastric adenocarcinoma is widely known; however, it is not entirely understood how bacterial infection is closely related to the genesis of follicular gastritis and some types of gastric lymphoma. Diagnosing and pathogenic mechanisms follicular gastritis remain challenging. Therefore, this article aims to examine the role of H. pylori in the development of follicular gastritis. In addition, it emphasizes the clinical and histopathological fundamentals. A broader overview of follicular gastritis is presented, and implementing preventive strategies, such as H. pylori eradication remains the standard treatment.
Aceptabilidad y resultados de detección de infección por virus de hepatitis B, C y virus de inmunodeficiencia humana mediante test rápido en pacientes sometidos a endoscopía ambulatoria
Authors: Muñoz Ana , Espino Alberto , Soza Alejandro , Arenas Alex , Gran José , Norero Blanca
Published: January 2025

Introducción: Las infecciones por virus inmunodeficiencia humana (VIH), hepatitis B (VHB) y C (VHC) son un problema global de salud pública. En 2019 había 295,9 millones de personas con hepatitis B crónica y 57,8 millones con VHC y menos del 20% conocían su estado. En 2017 había 37 millones de personas con VIH y el 75% estaba diagnosticado. Crear estrategias accesibles de tamizaje sigue siendo un desafío. El uso de tests de diagnóstico rápido (TDR) es una opción económica y simple. La unidad de endoscopía es un lugar ideal dado su alto flujo de pacientes y personal calificado. Objetivos: Evaluar el uso y aceptación de la aplicación de dos TDR que detectan VIH, VHB y VHC en pacientes que ingresan a estudio endoscópico y conocer el porcentaje de rechazo a su aplicación. Materiales y métodos: Se realizó un estudio piloto observacional transversal. Se enrolaron adultos que ingresaron ambulatoriamente a Centros de Endoscopía en Santiago y se aplicaron dos TDR: Montebio y HCV/HBsAg/HIV Rapid Test previa consejería y consentimiento informado. Resultados: 358 de 375 pacientes (96%) aceptó el test, 79% fueron mujeres. La edad promedio fue 50 ± 17 años. Un sujeto fue reactivo para VHC en ambos tests (0,27%). No hubo reactivos para VHB/VIH. 17 pacientes (4,2%) rechazaron el examen. El porcentaje de rechazo según género fue 8,8% (hombres) vs. 2,7% (mujeres) (p=0,009). La experiencia global fue positiva y el 98% recomendaría el proceso. Conclusiones: El uso de TDR en endoscopía representa una oportunidad de detección sistemática de pacientes infectados con adecuada aceptación.
Ascitic fluid amylase-to-serum amylase ratio to predict pancreatic duct leaks causing ascites
Authors: Wasserman Reid , Ali Al Qaffas Ahmed , Darwin Peter , Mönkemüller Klaus , Okolo Patrick , Yeaton Paul , Kesar Vivek , Kesar Varun
Published: January 2025

Objectives: Pancreatic duct leaks can cause ascites, and fluid amylase can be used as a marker to suggest pancreatic duct leak; however, there is no reference parameter or cutoff value for diagnosis. We assessed whether a novel ratio of ascitic fluid to serum amylase can reliably predict pancreatic leaks and need for endoscopic retrograde cholangiopancreatography (ERCP). Materials and methods: Patients who had fluid amylase from ascitic fluid and serum amylase within one week of confirmed pancreatic leaks via ERCP were included along with appropriate medical and surgical controls. Results: A total of sixteen patients were included in the study group. The mean ascitic fluid amylase to serum amylase ratio in the study group was 243, and 0.3511, and 0.9406 for medical and surgical controls respectively. The cutoff ratio to predict pancreatic leaks was 6.89 with 100% sensitivity and specificity (p-value 0.0000000000001347). Conclusions: Patients with a fluid to serum amylase ratio of at least 6.89 should be considered high risk for pancreatic leak with consideration to proceed directly to ERCP.
Peroral endoscopic myotomy in a 4-year-old patient
Authors: Hrunka Matěj , Martínek Jan , Tůma Jiří , Dohnalová Lucie , Jabandžiev Petr
Published: January 2025

Peroral endoscopic myotomy (POEM) is a legitimate method for treating esophageal achalasia. It has been used in the Czech Republic since 2012. In the adult patient population, use of this method is already quite widespread. In pediatrics, however, our experience with the procedure is still limited. In this case report, we present on the case of what is, according to our best knowledge, the youngest Czech child with esophageal achalasia who, at just under 4 years of age, successfully underwent POEM. Prior to treatment, the child was often sick and failing to thrive, suffering from chronic cough and recurrent vomiting. Thanks to this minimally invasive method, the child can now fully develop her growth potential without the limiting symptoms of esophageal achalasia. Due to the patient’s age, it was not possible to perform standard high-resolution esophageal manometry. The diagnosis was finally confirmed by innovative endoluminal impedance planimetry, called functional luminal imaging probe (FLIP) topography, which we performed perioperatively. Our patient’s case confirms that POEM can be considered an alternative equivalent to laparoscopic or classical myotomy in pediatrics. In the hands of an experienced endoscopist, it is a safe and effective procedure.

Keywords
POEM, achalasia, peroral endoscopic myotomy, pediatric, endoluminal impedance planimetry
Obesity and hypertension: recommending challenging bariatric surgery in hypertensive patients?
Authors: Dameski Emilija
Published: January 2025

The long-known relationship between obesity and a significant increase in cardiovascular diseases, including hypertension, is well established. The prevalence of hypertension increases proportionally with rising body weight and represents a significant factor in the connection between obesity and mortality from cardiovascular diseases. It has been demonstrated that even within a normal BMI range, an increase in weight leads to a corresponding rise in blood pressure. The main mechanisms by which obesity negatively affects blood pressure include increased blood volume, changes in the vascular system, activation of the renin-angiotensin system, insulin resistance, inflammatory processes, and sleep apnea. In this case study, we aim to demonstrate the effect of bariatric surgery, specifically gastric plication, on the course of hypertension. The case study shows that bariatric surgery in a patient with class I obesity and poorly controlled hypertension led to a significant reduction in body weight and also contributed to a decrease in polypharmacy.

Keywords
obesity, hypertension, bariatric surgery
Nutrition of patients after bariatric surgery with high physical activity
Authors: Hes Filip
Published: January 2025

Bariatric surgery is now considered a safe and effective long-term method for treating obesity and related health issues. Many people preparing for bariatric surgery tend to be less active. However, it is important to recognize that physical activity is beneficial for health regardless of the procedure. After bariatric surgery, it is crucial to increase the level of physical activity. An active lifestyle following the procedure helps reduce body fat and maintain muscle mass, contributing to better body composition. Maximum oxygen consumption (VO2 max) improves, fat oxidation is supported, and muscle strength increases. Over the long term, this enhances the quality of life, helps prevent weight regain, supports the maintenance of healthy eating habits, and improves overall mental well-being.

Keywords
bariatric surgery, nutrition, physical activity, bariatrics
Adherence to therapy in patients with inflammatory bowel disease on subcutaneous biologic therapy
Authors: Kolář Martin , Lukáš Milan
Published: January 2025

Introduction: Nonadherence is a problem in the treatment of chronic diseases including inflammatory bowel disease (IBD) and according to the literature, adherence is not sufficient in a quarter of patients. The consequence is an increased risk of treatment failure and disease relapse. Non-adherence plays a significant role in the case of home application of subcutaneous biological therapy (BT). The aim of this study is to evaluate the adherence of conventionally monitored IBD patients with subcutaneous BT in comparison with the use of telemedicine monitoring. Methods: Retrospective data from a single IBD centre on the frequency of visits and medication dispensed in patients were used to assess adherence, with the calculation of the Medication Possession Ratio (MPR). A cohort of patients managed using the IBD Assistant platform, with activated online notifications when an application was required, was compared with a control group of conventionally monitored IBD patients matched by treatment type, diagnosis, gender and age. A secondary endpoint was monitoring of serum drug levels in a subpopulation of adalimumab patients. Results: The study included 69 patients with subcutaneous BT active between July 2022 and July 2023 on the IBD Assistant platform. A control group of 138 conventionally monitored patients was matched to this group in a 2: 1 ratio. The mean age of the patients was 40.6 ± 11.1 years; 43.5% were male. Crohn‘s disease was diagnosed in 83.1% of patients. Adalimumab was administered to 91.3% of patients, 7.2% of patients received subcutaneous vedolizumab and 1.5% of patients received golimumab. Median follow-up was 517 days. Adherence as assessed by MPR was high in both the telemedicine and conventional groups (0.960 ± 0.084 vs. 0.967 ± 0.094; P = 0.6123). The proportion of non-adherent patients with MPR < 0.86 was 8.8% and 8.0%, respectively (P = NS). In the whole cohort, adherence was significantly lower in women and tended to be higher in patients with ulcerative colitis. Patient age did not play a role. The proportion of nonadherent patients was significantly higher in patients with low levels of adalimumab (36.8 vs. 4.9%; P = 0.0002). Conclusion: Although the overall adherence to subcutaneous BT is relatively high and independent of patient follow-up, MPR assessment can help identify at-risk patient groups. Low drug (adalimumab) levels are the result of nonadherence in one third of cases.

Keywords
inflammatory bowel disease, biologic therapy, adherence, medication possession ratio
Hereditary hemochromatosis in practice
Authors: Kollár Martin
Published: January 2025

ereditary hemochromatosis is a disease in which iron accumulates excessively in the body and it is one of the most common congenital metabolic diseases. The case report presents a patient from practice with acute upper gastrointestinal bleeding, with increased serum iron and ferritin values, without elevation in bilirubin, transaminases or obstructive liver tests, in whom further examination revealed genetic hemochromatosis.

Keywords
ferritin, HFE gene, hereditary hemochromatosis, erythrocytapheresis
Primary laryngeal B lymphoma with plasmocyoid diff erentiation – a case report
Authors: Bonaventurová Markéta , Lukeš Petr , Kalfeřt David , Galiyeva Liliya , Dekojová Tereza , Campr Vít , Plzák Jan
Published: January 2025

Overview
Primary non-Hodgkin laryngeal lymphoma is a rare disease with a prevalence under 1% of all tumors of the larynx. It originates mostly in the supraglottis region and presents itself as a nonulcerative solid tumor. Patient can suffer from dysphonia, dysphagia, foreign body sensation, dyspnea or even suffocation. Diagnosis is based on microlaryngoscopy and histopathology. The treatment options are chemotherapy, immunotherapy, radiotherapy or their combination. In our report, we present the case of an 86-year-old woman with a history of over a year of progressive dysphonia and dyspnea. Samples were taken during direct microlaryngoscopy under general anesthesia. In frozen sections, there was a high suspicion of lymphoma, and that was also confirmed from definitive histopathology. The patient was given over to the hemato-oncologist. There was a prompt response to chemotherapy, with relief from the symptoms even after the first dose. The aim of our study is to highlight this condition in the differential diagnosis of laryngeal tumors and the causes of dyspnea, summarize the knowledge of the disorder and the modality of treatment according to recent literature.
Atypical course of orbital complication in acute rhinosinusitis – a case report
Authors: Červený Květoslav , Balatková Zuzana , Kalfeřt David , Plzák Jan
Published: January 2025

nflammatory conditions affecting the soft tissues of the orbit (orbitocellulitis) are one of the most common complications of acute rhinosinusitis affecting both children and adult patients. Although they are rather rare in today‘s antibiotic era (incidence is in percent units), it is still a condition that threatens the patient not only with loss of vision, but also with life, requiring early and correct treatment. Our case shows the course of complicated orbitocellulitis in a 31-year-old internally healthy patient hospitalized in our clinic. Despite early surgical intervention and drainage of the medial abscess mass in the orbit, there was only temporary improvement, while another abscess cavity was found laterally in the orbit, necessitating reoperation and drainage of the abscess by an external approach. Therapeutic process and used diagnostics and treatment are described in this case report. Symptomatology, recommended management of diagnostics and treatment of complications of acute rhinosinusitis are discussed.

Keywords:
FESS – rhinosinusitis – complications – orbitocellulitis – phlegmon
IgG4-associated diseases in the ENT area – a case report
Authors: Vojtová Michaela , Balatková Zuzana , Kalfeřt David , Plzák Jan
Published: January 2025

IgG4-related diseases (IgG4-RD) represent a group of rare systemic inflammatory conditions of unknown etiology and uncertain pathogenesis. Clinically, a wide range of symptoms can be observed in the ears, nose, and throat (ENT) area, depending on the tissue affected by the disease. Diagnosis is challenging relying on clinical presentation, histopathological evidence, radiological findings, and laboratory tests. Therapy typically involves long-term corticosteroid treatment often combined with immunosuppressive therapy. In our work, we present a case study of a patient with an extensive parapharyngeal space tumor, initially clinically and radiologically suggestive of malignancy, subsequently confirmed as an IgG4-related disease. The following article describes the clinical symptomatology of IgG4-RD in ENT and outlines the diagnostic approach to the presented case. Finally, the findings are summarized, emphasizing the necessity of multidisciplinary collaboration for proper differential diagnosis.

Keywords:
IgG4-related diseases – IgG4-RD – parapharyngeal space tumor
МЕЖКУЛЬТУРНАЯ КОММУНИКАЦИЯ В СОВРЕМЕННОЙ ДИПЛОМАТИИ: ПРОБЛЕМЫ, СТРАТЕГИИ И РОЛЬ ТЕХНОЛОГИЙ
Authors: Сарыбаев М.С. , Мургабаева А.С. , Есбергенова Г.Б. , Абдихапарова Г.А.
Published: January 2025

Современная дипломатия сталкивается с многочисленными вызовами, связанными с культурными различиями, что делает межкультурную коммуникацию важным элементом успешного международного взаимодействия. В статье исследуются проблемы, стратегии и роль технологий в межкультурной коммуникации, применяемой в дипломатии. Основное внимание уделено важности культурной компетентности как ключевого элемента эффективной дипломатической практики, которая способствует успешным переговорам, разрешению конфликтов и построению долгосрочных международных отношений. Используя качественную методологию, статья анализирует теоретические основы межкультурной коммуникации, включая такие концепции, как теория управления тревогой и неопределенностью, а также модели высоко контекстной и низко контекстной коммуникации, предложенные Эдвардом Т. Холлом. Эти теории помогают объяснить, как культурные различия влияют на восприятие, поведение и результаты дипломатических взаимодействий. В исследовании также рассматриваются конкретные примеры из дипломатической практики, которые демонстрируют влияние культурных факторов на эффективность переговоров. Особое внимание уделено различиям в коммуникации между западными и не-западными культурами, а также значению эмпатии, активного слушания и адаптации дипломатов к культурным особенностям. Также подчеркивается роль технологий, которые, с одной стороны, облегчают взаимодействие между государствами, а с другой—могут создавать новые проблемы, связанные с потерей культурных нюансов. Статья завершается выводом о важности интеграции культурной осведомленности в дипломатическую практику, включая использование новых технологий и методов обучения, что позволяет дипломатам эффективно преодолевать культурные барьеры, способствовать международному сотрудничеству и улучшать результаты дипломатических взаимодействий в глобализированном мире.
THE EMPLOYMENT QUOTA SYSTEM FOR INDIVIDUALS WITH DISABILITIES IN KAZAKHSTAN: EXPLORING POLICY, IMPLEMENTATION, CHALLENGES, AND SOLUTIONS IN THE CONTEXT OF GLOBALIZATION
Authors: Мaulen A. , Orynbassarov D. , Agybay Zh.R.
Published: January 2025

The main objective of this article is to bridge the research gap by providing a comprehensive background on the development of Kazakhstan's quota employment policies for individuals with disabilities within the broader context of the globalization process. The research aims to evaluate the disparities between policy formulation and execution, considering how international practices have shaped and influenced these policies, as well as Kazakhstan's awareness of and alignment with these global standards. Additionally, the article seeks to suggest practical methods to improve the policy's efficacy in fostering greater inclusivity inemployment opportunities in both the public and private sectors.This research contributes to the existing body of literature by focusing on Kazakhstan's specific situation regarding the employment of individuals with disabilities and thequota system. The study's findings offer valuable insights into the challenges and opportunities for improving inclusivity in the labor market in Kazakhstan, which can be relevant for other countries facing similar policy developments.The research uncovers the historical development of Kazakhstan's quota employmentpolicies and identifies key challenges in their implementation. It highlights discrepancies between policy formulation and execution, which have affected the effectiveness ofthe quota system in promoting inclusivity. Additionally, the study identifies practical recommendations to enhance the policy's impact and create more opportunities for disabled individuals in the workforce.
Photo-Feminists: The Inter-textual Discussion of Eighteenth-Century Periodical Frontispieces
Authors: Sutton-Bennett Karenza
Published: January 2025

The visual afterlife of the two frontispieces from the first volume of Eliza Haywood’s periodical, The Female Spectator (1744-46) promotes the argument that middling women should be allowed to learn the same proto-disciplinary topics that men studied by representing how women could include both amusements and informal learning in between their duties as wives and mothers. The Female Spectator’s frontispiece, the emblem to Frances Brooke’s The Old Maid (1755-56), the frontispiece to Charlotte Lennox’s The Lady’s Museum (1760-61) and the 1789 frontispiece to The Lady’s Magazine (1770-1847) have the common element of the image of Minerva to visually continue the debate of female knowledge. Each image not only responds to the Female Spectator’s depiction of women learning, but also builds on the previous periodical’s visual response with time specific portrayals of the changes in balancing distractions with informal education. Analyzing the visual representations of women learning within the context of Michael Warner’s argument on the developing overlapping publics and counterpublics in the eighteenth century, and Tita Chico’s argument on the coquet figure reforming through proto-disciplinary knowledge, brings attention to the changing notion that middle-class women did not have the interest, access, and capability to learn proto-disciplinary knowledge. This paper concludes that the progression of the images represents the development and gradual acceptance of women’s informal education through the visual and textual representations of women studying natural philosophy, ancient history and moral philosophy in the frontispieces. Thus, Haywood’s periodical acts as a catalyst for subsequent periodicalists’ debates on women’s education.
Jumping Pens and Historical Vertigo: Teaching Cavendish in the Twenty-first Century
Authors: Thell Anne M.
Published: January 2025

"Jumping Pens" considers "historical and epistemological vertigo" as a useful pedagogical rubric for teaching the works of Margaret Cavendish (1623-73) in contemporary university classrooms. Specifically, it looks back across more than a decade of teaching Cavendish in diverse settings in order to show how exciting this author can be for students who are just starting out in the discipline of literary studies. As this essay argues, Cavendish can make us all better, more self-aware instructors, while also developing critical and historical acumen in our students.
A Review of Kristin M. Girten's Sensitive Witnesses: Feminist Materialism in the British Enlightenment
Authors: West Peter
Published: January 2025

A review of Sensitive Witnesses by Kristin M. Girten by Peter West.
An Argumental Discourse Before All: An Approach to Teaching Cavendish
Authors: Shaheen Jonathan L
Published: January 2025

Cavendish directs readers of Observations upon Experimental Philosophy to begin engaging her work through "An Argumental Discourse." In this piece, I describe a way of thinking about the structure of that piece and how to understand two of its major moments in relationship to standardly taught material. The first moment is the dilemma about how inanimate matter is moved, with its response centered on treating a horse and its rider as a paradigm example of causation. The article shows how the argument involves Cavendish's conceptions of causation, minds, bodies, and mind-body interaction. The second moment has to do with the relationship between infinite divisions and atomism. The article distinguishes Cavendishian and Cartesian conceptions of division in order to relate Cavendish's thinking about division and atoms to Descartes's well-known argument against atomism. The discussion shows how a wide variety of central philosophical issues can be taught and interestingly complicated while requiring students to engage with fewer than 16 pages of reading.
Introduction: Intergenerational Thinking
Authors: Binhammer Katherine
Published: January 2025

This introduction to a conversation on Intergenerational Thinking that first began at the American Society of Eighteenth Century Studies in Toronto, March 2024, establishes the importance of dialogue across generations in feminist eighteenth-century studies. It synthesizes the methods the participants engage to think with past scholars, rather than disavow such work. While the topics discussed are diverse -- feminist history, Phillis Wheatley, Indigenous eighteenth-century archives, climate catastrophe and Charlotte Charke – the writers share an approach to generational thinking grounded in a critique of the assumption that the new is always better.
A Review of Jennifer Maclure’s The Feeling of Letting Die: Necroeconomics and Victorian Fiction
Authors: Zigarovich Jolene
Published: January 2025

A review of Jennifer MacLure’s The Feeling of Letting Die: Necroeconomics and Victorian Fiction by Jolene Zigarovich.
A Review of Maeve E. Kane's Shirts Powdered Red: Haudenosaunee Gender, Trade, and Exchange across Three Centuries
Authors: Adams-Campbell Melissa
Published: January 2025

A review of Shirts Powdered Red: Haudenosaunee Gender, Trade, and Exchange across Three Centuries, by Maeve Kane
Hukuk Yargılamasında Özel Hukuk Tüzel Kişilerinin Adlî Yardımdan Yararlanması Meselesi
Authors: Erzeybek Hakan
Published: January 2025

Özel hukuktan kaynaklı uyuşmazlıklarının çözümünde, devletin adalet hizmetlerinden yararlanılabilmesi, bir kısım yargılama giderlerinin ödenmesine bağlıdır. Bu durum, ekonomik yeterliliğe sahip olmayan kişilerin yargısal makamlara müracaatlarının önünde ciddi bir engel oluşturmaktadır. Adlî yardım kurumu ile ekonomik yeterliliğe sahip olmayan kişilere yargısal makamlar nezdinde iddia veya savunmalarını gerçekleştirebilmeleri için ödemeleri gereken yargılama giderlerinden geçici olarak muafiyet tanınmaktadır. Adlî yardım kurumunun önemi dikkate alındığında, adlî yardımdan yararlanabilecek kişilerin belirlenmesi de ayrı bir öneme sahiptir. Hukuk Muhakemeleri Kanunu m. 334/II’de kamuya yararlı dernekler ve vakıflar haricindeki özel hukuk tüzel kişilerinin adlî yardım hükümlerinden yararlanıp yararlanmayacağı konusunda açık bir yasal düzenleme yapılmamıştır. Bu durum, düzenlemenin kapsamı dışında kalan özel hukuk tüzel kişilerinin adlî yardım hükümlerinden yararlanıp yararlanamayacağı meselesinde öğretide ve uygulamada farklı tartışmaları da beraberinde getirmiştir. Nitekim Anayasa Mahkemesi’nce özel hukuk tüzel kişilerinin adlî yardım hükümlerinden yararlanmasını kategorik olarak sınırlayan düzenlemenin Anayasa’ya aykırı olduğuna ve iptaline karar verilmiştir. Çalışmamızda, Anayasa Mahkemesi’nce verilen iptal kararının yansımaları, karşılaştırmalı hukukta yer alan düzenlemeler, bilimsel ve yargısal içtihatlar ışığında medenî usûl hukuku açısından özel hukuk tüzel kişilerinin adlî yardımdan yararlanması meselesi üzerinde tespit ve değerlendirmelerde bulunulmaktadır.
Comparative Literature and the Quest for Global Literary Theory: Exploring a West African Margin
Authors: Łukaszyk Ewa A.
Published: January 2025

This article reflects on the intellectual aspirations and current challenges faced by the discipline of Comparative Literature. The challenge identified comes from the global margins and the necessity of integrating the plurality of non-colonial lega-cies in the syncretic vision of global literary studies. The case study presented in the article, the literature of Guinea-Bissau, is considered not in the usual inter-literary context of Lusophone universe, but in its regional, West African cultural history, rich in tribal legacies and Islamic influences. The regional focus permits to emphasize the plurality of local languages, legacies of oral literature associated with them, as well as non-European literacy. The focus proposed permits us to see the literature of Guinea-Bissau not as an emergent phenomenon, but as a conclu-sion of long-lasting cultural processes reaching, with the postcolonial writing, their stage of exhaustion rather than auroral moments.
Pourquoi ces choses et non pas d’autres: Attention and Lists in Comparative Literature
Authors: Ferreira Bernardo Diniz
Published: January 2025

Taking a short quotation from Le Mariage de Figaroby Beaumarchais as motto, this article reflects on important issues of comparative literature, namely, questions of inclusion and exclusion in the delimitationof the discipline’s boundaries. In the con-text of recent discussions on the shifting role and modes of attention in contemporary society (and following Bernard Stiegler), it argues that the issue can be seen in broad terms as a matter of attention and its techniques, and that comparative literature can be understood as both the practical and theoretical study of attention. Finally, it briefly considers the pivotal role of listmaking within the material productions of comparative literature (canons, syllabi, anthologies) as manifestations of this atten-tional identity.