bluuebunny/crossref_metadata_2025 huggingface dataset:
Mycosis Fungoides: Histopathology and T Cell Receptor Gene Rearrangements in Indian Patients
Authors: Umarji Seema A. , Tirumalae Rajalakshmi , Prabhu Jyothi S. , Aiyappa-Maudsley Radhika
Published: November 2024

Introduction:

Mycosis fungoides (MF) is the commonest cutaneous T cell lymphoma. MF presents in three stages the patch, plaque, and tumor. The distinction of patch-stage MF from inflammatory dermatoses is a diagnostic challenge.

Need for the Study:

MF shows T cell receptor gamma and beta gene rearrangements (TCRG and TCRB), detectable by polymerase chain reaction (PCR). Data about the clonality of infiltrates in our population and their utility in diagnosis is lacking.

Materials and Methods:

Skin biopsies from 50 patients with mycosis fungoides from January 2007 to July 2015 were studied for microscopic features. TCR gamma and beta gene rearrangement assays were performed on 14 patients where formalin fixed paraffin embedded (FFPE) was available. DNA was extracted using the phenol-chloroform method. PCR was performed using primers from Invivoscribe Identiclone assay. Clonality was analyzed using Agarose gel electrophoresis.

Results:

Of the 50 cases, 37 were patch, nine were plaque, and four were tumor stage. All cases showed disproportionate lymphocyte epidermotropism, 38 showed lymphocyte atypia, and 33 showed adnexotropism (11 eccrotropism and 22 folliculotropism). Clonality was assessed in 14 cases. Of these, 3/9 patch stages were monoclonal (1/3 monoclonal for beta, and 2/3 monoclonal for gamma and beta). 3/3 plaque stage MF was monoclonal (1/3 for gamma, 2/3 for both), and 1/2 tumor stage MF was monoclonal for gamma and beta receptors.

Conclusion:

The patch stage was the most common presentation. TCR gene rearrangements were noted in 50% of MF, with TCR gamma rearrangements being more common. Plaque and tumor stages yielded higher positive rates.
Epidemiological Profile and Correlates for Left Ventricular Diastolic Dysfunction among Patients Attending a Tertiary Health Facility in India
Authors: Yadav Bijay P. , Kushwaha Poonam
Published: November 2024

Background:

There is an increasing recognition that congestive heart failure (CHF), caused by diastolic dysfunction (DD) (diastolic heart failure), is common and causes significant morbidity and mortality.

Methods:

The institution-based cross-sectional study was conducted among 119 subjects to determine the epidemiological profile, and regression analysis was used to evaluate the association of clinico-social correlates with the likelihood of developing DD.

Result:

The mean age of subjects was 51.6(±17.7) years. The mean systolic (SBP) and diastolic blood pressures (DBP) were 130(±18.9) mm Hg and 82.1(±11.1) mm Hg, respectively. Thirty-three (27.7%) subjects were hypertensive. Twelve (10%) were diabetic and experienced heart failure. DD was present in 54 (45.4%) subjects. Age, diabetes, ejection fraction (EF), and interventricular septal thickness in diastole (IVSd) were significant (P < 0.05) correlates of DD. Mean values of age, body mass index (BMI), EF, IVSd, and left ventricular posterior wall thickness in diastole (LVPWD) were higher in subjects with DD. Hypertension contributed to 1.63 times greater odds of developing DD.

Conclusion:

The prevalence of DD increased with age among hypertensive and diabetic participants. Preventive strategies directed toward identifying subclinical signs of early stage and aggressive blood pressure and blood sugar control are likely to offer the greatest promise for reducing the incidence of DD.
Platelet Indices: Predicting Retinopathy in Patients with Type 2 Diabetes Mellitus
Authors: Paul Arijit , Das Soumyadip , Bose Koushik , Karmakar Rupam
Published: November 2024

Background:

Diabetes mellitus (T2DM) is a metabolic disorder, characterized by insulin resistance and varying degrees of hyperglycemia, leading to several macrovascular and microvascular complications. In recent years, altered platelet morphology and dysfunctions are reported in patients with T2DM. Platelet indices, namely plateletcrit (PCT), mean platelet volume (MPV), and platelet distribution width (PDW), can predict altered platelet morphology and dysfunction which leads to microvascular complications, such as retinopathy.

Aims:

This study was aimed at comparing platelet indices in individuals with impaired fasting glucose, T2DM patients, and also in patients with retinopathy; and to determine any association between them.

Study Settings, Design, Material, Methods, and Statistical Analysis:

A cross-sectional observational study was undertaken on 200 patients attending diabetic OPD of our institution over a period of 18 months. The obtained data were analyzed using suitable statistical software.

Results:

We found that mean values of platelet indices (MPV, PCT, PDW) are significantly higher in diabetics (11.73 fl, 0.238%, 17.01 fl) than in persons with impaired fasting glucose (9 fl, 0.195%, 11.23 fl). Moreover, they are significantly higher in patients with retinopathy (12.54 fl, 0.257%, 19.05 fl) than in patients without retinopathy (10.21 fl, 0.205%, 13.29 fl). We also found a positive correlation between platelet indices and HbA1C.

Conclusion:

Platelet indices can easily determine platelet dysfunction and thereby can predict the presence of retinopathy. They may serve as economical and readily available tool in monitoring diabetic patients.
Outcomes of microcatheter-assisted trabeculotomy in adult patients with primary congenital glaucoma and juvenile open-angle glaucoma: A case series
Authors: Schreurs Ine , Stalmans Ingeborg , Lemmens Sophie
Published: November 2024

Trabeculotomy is conventionally performed using a rigid probe, allowing for 180° trabeculotomy. More recently, microcatheter-assisted 360° trabeculotomy (MCAT) has shown safe and effective results in pediatric glaucoma cases, particularly in primary congenital glaucoma (PCG) and to a lesser extent in juvenile open-angle glaucoma (JOAG). This case report highlights the successful intraocular pressure (IOP) control following iTrack®-assisted trabeculotomy in one adult with PCG and two with JOAG. Four eyes of three adults, aged 50, 28, and 45 years, underwent MCAT for uncontrolled PCG or JOAG, with no prior surgical history. No major complications were observed. Postoperatively, IOP ranging from 11 to 15 mmHg was achieved without the need for topical therapy or reoperation during a follow-up period of 12–14 months. These cases suggest that MCAT is both effective and safe for adults with PCG or JOAG requiring surgery.
Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring
Authors: Lee Hamin , Nam Jin-Wu , Kim Mi Kyung , Kim Inah , Kim Yu-Mi , Park Boyoung
Published: November 2024

The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study’s design, data collection methods, baseline socio-demographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants’ self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.
Combustion and Emissions Comparison between a Diesel and a Dimethyl
Ether (DME) Off-Highway Compression Ignition Engine
Authors: Apostolou Christos , Elliott Thomas , Rutledge John , Butcher Daniel , Long Edward , Spencer Adrian
Published: November 2024

Dimethyl ether (DME) is a promising substitute for diesel as a fuel in heavy-duty
engines. This article presents the comparison between a diesel- and a
DME-powered compression ignition engine. The diesel-powered version was
initially characterised at a range of operating points before being converted to
operate on DME. This was achieved by replacing fuel system components with
bespoke DME-compatible engine parts. An off-board fuel pressurisation and
conditioning system was designed to replace the existing high-pressure fuel
pump, while maintaining all other engine hardware and components.

Engine behaviour, in terms of combustion and emissions on both fuels was
examined. Firstly, the effect of varying recirculated exhaust gas (EGR)
concentration at constant excess air ratio, combustion phasing (CA50) and equal
fuel delivery rate (by energy input) was interrogated. DME combustion was
significantly faster, as combustion duration was reduced by around 30%, in some
cases, when comparing to diesel. The DME-powered version of the engine was also
found to produce lower carbon monoxide (CO) and unburned hydrocarbon (uHC)
emissions. Up to a threefold reduction was measured, depending on engine load.
NOx emissions worsened, when transitioning to DME, for the medium
load case. The low-load EGR sweep showed minimal changes in NOx
emissions. High-pressure EGR can significantly lower DME NOx emissions to below
the diesel baseline levels, depending on engine load and speed, as demonstrated
by the results of the 8-mode test runs. Given the extremely low particulate
emissions, higher EGR concentrations can be utilised by engines operating on
DME. Despite resorting to the use of bespoke equipment in this study, the
challenges faced during the engine conversion were deemed manageable with the
currently available technology.
Pengaruh Jus Semangka Dalam Menurunkan Tekanan Darah Pasien Hipertensi
Authors: Umrah Yufriza , Rosjidi Cholik Harun , Balaka Kemal Idris
Published: November 2024

Hipertensi adalah suatu gangguan pada pembuluh darah dengan suplasi nutrisi dan oksigen  yang mengalami hambatan untukmencapai jaringan tubuh, sehingga memicu jantung untuk bekerja keras dalam memenuhi kebutuhan tersebut. Secara nonfarmakalogi manajemen hipertensi dapat dilakukan dengan berbagai terapi sepertiterapi jus semangka.Penelitian ini bertujuan untuk mengidentifikasi pengaruh terapi jus semangka dalam menurunkan tekanan darah pada penderita hipertensi di wilayah kerja Puskesmas Kulisusu.
Metode yang digunakan dalam penelitian ini adalah pra eksperimenone group pre-post test design.Sampel penelitian berjumlah 25 orang yang ditentukan dengan teknik purposive sampling.Penelitian ini memiliki variabel independent jus semangka, sedangkan variabel dependentnya adalah tekanan darah pada penderita hipertensi.
Hasil penelitian yang dianalisis dengan uji Wilcoxon Signed Rank Testyang menunjukan bahwa  jus semangka dapat menurunkan tekanan darah pada penderita hipertensi yang ditandai dengan p value  < α (0,00<0,05).
Simpulan penelitianadalah  jus semangka secara efektif dapat menurunkan tekanan darah  penderita hipertensi diWilayah Kerja Puskesmas Kulisusu.Saran penelitian diharapkan Puskesmas Kulisusudapat menjadikan jus semangka sebagai salah satu cara dalam mengontrol dan menurunkan tekanan darah  pada pasien hipertensi.
Hubungan Pengetahuan Tentang Covid-19 Dengan Kepatuhan Protokol Kesehatan pada Siswa Kelas XI
Authors: Tamburaka Henny Rachmawati , Umrana Siti , Saranani Muhaimin
Published: November 2024

Absctract Crisis Center of Indonesian Ministry of Health stated that until April 2022 in Southeast Sulawesi Province, 25,550 people were confirmed positive for Covid-19 with 565 cases of death, in Konawe Selatan Regency there were 1,261 people with Covid-19 with 35 deaths. The increase in Covid-19 instances can be prevented if the community has a good understanding and knowledge, especially in the youth group, knowledge about Covid-19 is interpreted as a result of knowing from the public about the disease, how to prevent, treat and complications that may occur after exposure to a disease. The purpose of the study was to determine the relationship between knowledge and adherence to the Covid-19 health protocol in class XI students at SMA Negeri 8 Konawe Selatan. This type of research is quantitative with a cross-sectional study design with a sample of 66 students. The results of the study describe students' knowledge of covid-19 in the good category as many as 54 people (54%) and the category of lack of knowledge about covid-19 as many as 12 people (18.2%). Adherence to the health protocol in the obedient category was 21 people (31.8%) and the less compliant category was 45 people (68.2%). The results of the statistical test obtained a p value = 0.4 (> 0.05) meaning that there was no relationship between knowledge about COVID-19 and student compliance with health protocols. It is recommended to the school that before starting the learning process always remind students about covid-19 and compliance with post-pandemic health protocols according to government instructions as a form of joint vigilance.
Jung Tipolojisi Bağlamında Kişilik Tipi Analizi: Denizin Çağırışı Romanında Öğretmen Karakteri
Authors: Ünlü Aslı
Published: November 2024

Kemal Bilbaşar’ın ilk romanı olma özelliğini taşıyan Denizin Çağırışı yazarın 1941 yılında yayımladığı önemli ve özgün bir eserdir. Bilbaşar’ın daha sonra kaleme aldığı ve farklı bir üslûp yakaladığı Cemo ve Memo gibi romanları daha fazla öne çıkmış, Denizin Çağırışı adlı romanı sözü edilen eserlerinin gölgesinde kalmıştır. Birçok araştırmacı tarafından Türk edebiyatındaki psikolojik anlamda yabancılaşmanın ilk örneği olarak kabul edilen Denizin Çağırışı, romanda adı anılmayan öğretmen karakterinin ruhsal dünyasını ele alan bir psikolojik tahlil romanı olma özelliğini taşır. Denizin Çağırışı bu bakımdan Türk edebiyatında psikolojik tahlilin başarılı ilk örneklerindendir. Bilbaşar, Denizin Çağırışı’nda zayıf karakterli, iradesiz, topluma yabancılaşmış, hayat karşısında başarısız olmuş bir öğretmeni ele almıştır. Öğretmenin bilinçaltı romanda “somut” bir unsur olarak karşımıza çıkmaktadır. Bu bakımdan söz konusu karakterin kişilik tipini tahlil etmek, Jung tipolojisi bağlamında psikolojik tipini tespit etmek mümkündür. Kemal Bilbaşar tarafından adeta çıplak bir biçimde okurun analizine sunulan öğretmen karakteri, Jung tipolojisi bakımından incelenmeye değer, karmaşık ve dikkat çekici bir roman kahramanıdır. Bu çalışmada Denizin Çağırışı romanının ana öznesi öğretmen karakterine odaklanılıp öğretmen karakterini Türk edebiyatındaki diğer karakterlerden farklı ve özgün kılan özelliklerden bahsedilecek, öğretmen karakterinin Jung tipolojisi bağlamında kişilik tipi tespit edilecektir.
On complete classes of valuated matroids
Authors: Husić Edin , Loho Georg , Smith Ben , Végh László A.
Published: November 2024

We characterize a rich class of valuated matroids, called R-minor valuated
matroids that includes the indicator functions of matroids, and is closed under
operations such as taking minors, duality, and induction by network. We exhibit
a family of valuated matroids that are not R-minor based on sparse paving
matroids. Valuated matroids are inherently related to gross substitute
valuations in mathematical economics. By the same token we refute the Matroid
Based Valuation Conjecture by Ostrovsky and Paes Leme (Theoretical Economics
2015) asserting that every gross substitute valuation arises from weighted
matroid rank functions by repeated applications of merge and endowment
operations. Our result also has implications in the context of Lorentzian
polynomials: it reveals the limitations of known construction operations.
Eugenio Trías, filósofo de posguerra
Authors: SUCASAS Alberto
Published: November 2024

La filosofía del límite de Eugenio Trías debe ser considerada un pensamiento de posguerra. Bajo la superficie de sus tesis teóricas actúa la conciencia de la barbarie del siglo XX. Este artículo propone fundamentar esa lectura a tres niveles. En primer lugar, identificando en el corpus las referencias expresas al horror perpetrado en la historia reciente. A continuación, mediante la explicitación del sustrato histórico de algunas de sus principales propuestas: el Principio de variación y la búsqueda de un equilibrio entre individuo y colectividad; la antítesis dominación/poder; el énfasis en la libertad. En tercer y último lugar, se identifica la inspiración trágica subyacente al conjunto de ese pensamiento.
Palabras clave: Límite, Tragedia, Barbarie, Posguerra, Poder.
Religiosity and Mental Well-Being among Mentally Ill People in Bangladesh
Authors: . Fazilatunnasa , Akter Mosammet Khaleda , Mallick Dipali Rani , Khatun Shanzida
Published: November 2024

Objectives: The study aimed to examine the relationship between religiosity and the mental well-being of mentally ill people. Methods: A correlational study was conducted among 112 mentally ill people with intact insight who were selected by using a convenience sampling technique. Data was collected through face-to-face interviews. After data collection, it was analyzed using descriptive and inferential statistics. Results: It was found that there was a strong positive significant correlation between religiosity and mental well-being. Religiosity was significantly associated with gender, marital status and duration of illness. Age, gender, marital status, occupation, monthly income, number of family members, duration of illness, religious activities and prayer were significantly associated with mental well-being. Conclusion: The study findings will contribute to generating knowledge about the potentiality of religiosity to improve quality of life and adaptation, reduce burden and stigma, and enhance early recovery by progressing mental well-being.
СТЕПЕНОВАЊЕ ТЕКСТОВА У НАСТАВИ СРПСКОГ КАО СТРАНОГ ЈЕЗИКА
Authors:   Универзитет у Београду, Филолошки факултет, Крајишник Весна
Published: November 2024

Текст је основно средство за усвајање и процјену вјештина читања и слушања у настави страног језика. Он представља и основу сваког уџбеника, али и тестова којим се врши евалуација ученичких постигнућа у усвајању језичких компетенција. У зависности од нивоа знања језика и узраста ученика, њихових потреба и циљева, текстови се прила- гођавају по теми, садржају, обиму и понајвише по избору лексике и граматичких садржаја. У Заједничком европском оквиру за живе језике (ЗЕОЈ), предложене су скале нивоа које илуструју опште способности разумијевања визуелне и аудитивне перцепције садржаја на страном језику. Иако у њима нису прецизно наведене тематске јединице, нити језички садржаји које је потребно усвојити за одређени ниво знања, дати су крајњи аутпути које ученик треба да произведе на сваком нивоу познавања језика. У складу са тим, креатори програма, уџбеника, као и сами наставници, морају да се ослоне на степеноване лексичке и граматичке садржаје. За потребе српског као страног језика нема прецизних и стандар- дизованих података који би се односили на степеновање језичких садржаја за сваки поје- диначни ниво знања, мада се, од појаве ЗЕОЈ-а на нашим просторима, почело озбиљније приступати овим питањима. У раду ће се указати на значај степеновања текстова, валидне критеријуме за њихово степеновање и дати два примјера за три нивоа знања на различи- тим врстама текстова.
СРПСКИ КАО СТРАНИ ЈЕЗИК НА МЕДИЦИНСКОМ ФАКУЛТЕТУ УНИВЕРЗИТЕТА У БАЊОЈ ЛУЦИ
Authors:   Универзитет у Бањој Луци, Филолошки факултет, Бабић Биљана , Поповић Александар ,   Универзитет у Бањој Луци, Филолошки факултет, Савић Александра ,   Универзитет у Бањој Луци, Филолошки факултет
Published: November 2024

Рад се бави питањима учења српског као страног језика на Медицинском факул- тету Универзитета у Бањој Луци. Основни циљ овог истраживања јесте да се освијетли и дубље анализира, како пракса у раду са студентима који долазе из различитих географ- ских, културних, политичких и језичких средина, тако и њихов однос према језику који им је у већини случајева потпуно непознат. Надаље, намјера овог рада свакако је да допринесе укупном квалитету наставе српског као страног језика будући да је упитник који су по- пунили студенти креиран тако да истовремено пружи информације о знању, мотивима и учењу страног језика. Основне хипотезе рада јесу да: а) не постоји разлика у одговорима на основу земље поријекла студената и б) студенти странци уче српски језик јер им је значајан у даљем школовању и будућем послу. Резултати нашег истраживања показују како постоји разлика између студената који долазе из различитих географских и културних средина, као и да њихова мотивација за учење и знање српског језика зависи готово искључиво од наставника. Захваљујући одговорима студената могуће је добити увид у њихов однос пре- ма српском као страном језику, али и креирати извођење наставе и вјежби у будућности.
La tenencia compartida como una garantía del derecho a la igualdad de los padres
Authors: Pozo Gordón Bolívar Iván , Trelles Vicuña Diego Fernando
Published: November 2024

La tenencia compartida de los padres sobre los menores hijos e hijas ha sido un tema objeto de diversas discusiones en los juicios de familia, siendo la tenencia uno de los aspectos más importantes a considerar por el juez al momento de tomar una decisión en la que se ha roto la convivencia familiar y los padres deciden separarse. En ese sentido, el tema objeto del presente estudio, puede considerarse como un derecho de los progenitores, por lo cual se deben respetar ciertas garantías para su pleno ejercicio, y una de esas garantías es sin duda la igualdad que debe prevalecer en el goce del derecho. Así, la tenencia compartida se convierte en un derecho no solo para el menor, sino también para los padres, y en el que la igualdad de condiciones debe ser tomada en cuenta por el juez para preservar los derechos tutelados.
Obstrucción unilateral del conducto ureterovesical del riñón izquierdo: reporte de caso
Authors: Vivas Pincay Luis Carlos , Taboada Pico Mentor Guillermo
Published: November 2024

La hidronefrosis es la expansión del sistema colector del riñón, que incluye la pelvis y los cálices renales, causada por un aumento de presión en esa área, lo que resulta en alteraciones morfológicas y funcionales. Se presenta a consulta una paciente canina de raza Cocker, 7 años que responde al nombre de Mara la cual fue atendida en la clínica Veterinaria Pet Service Samanes en la ciudad de Guayaquil, a la consulta presenta dolor abdominal, incontinencia urinaria, inapetencia y apatía. Al examen físico presenta condición corporal 5/3, FC  110 lpm, FR 30 rpm, temperatura corporal 39°C, TLLC 2 segundas, mucosas rosadas, presión arterial 120 – 90mmHg. Se realizan exámenes complementarios, en la ecografía se evidencian alteraciones en el conducto que conecta el riñón izquierdo con la vejiga, causado por una obstrucción de uno de los uréteres dando como resultado una hidronefrosis del riñón izquierdo, se realizó una nefroureterectomía.
Orquiectomía felina: comparación del uso de nudo quirúrgico miller y el nudo biológico
Authors: Montenegro Montenegro Cristian Andres , Ayora Muñoz Jorge Luis
Published: November 2024

La castración u orquiectomía es una intervención quirúrgica rutinaria en la práctica veterinaria, con múltiples beneficios que incluyen la prevención de enfermedades, el control de conductas indeseadas y la mitigación de problemas de sobrepoblación. El presente estudio, de enfoque cuantitativo, busca comparar la eficacia y el bienestar animal en dos técnicas de abordaje escrotal (incisión menor y mayor a 1 cm) en gatos machos sometidos a orquiectomía. Se evaluará una muestra de 40 felinos, con edades comprendidas entre los 6 y 96 meses, en la Clínica Veterinaria Solidaria de Cuenca, Ecuador. A través de la Escala de Vancouver, se evaluará la cicatrización de la herida quirúrgica, mientras que la Escala Facial Felina (Feline Grimace Scale) se empleará para evaluar el dolor postoperatorio en tiempo real. Se compararán las constantes etológicas faciales entre ambos grupos quirúrgicos en los días 0, 4, 8 y 12 postoperatorios. Los datos obtenidos serán analizados estadísticamente utilizando el software IBM® SPSS con el objetivo de determinar cuál de las técnicas de incisión evaluadas presenta menor tiempo de cicatrización, menor dolor postoperatorio y, en consecuencia, un mejor pronóstico para el bienestar del paciente. Los resultados de esta investigación contribuirán a optimizar las técnicas quirúrgicas de orquiectomía en felinos y a establecer protocolos estandarizados que garanticen un manejo postoperatorio más eficiente.
Comparação entre as vacinas mundialmente utilizadas para Neisseria meningitidis B: uma visão crítica
Authors: Santos Oliveira Giovanna , Segati Ana Flávia , Izeli Portilho Amanda , De Gaspari Elizabeth
Published: November 2024

A Neisseria meningitidis é um patógeno que causa grande impacto na saúde pública. O sorogrupo B representa um desafio em relação ao desenvolvimento de vacinas devido à similaridade estrutural de seu polissacarídeo capsular com o ácido polisiálico presente no tecido cerebral humano, que além de apresentar baixa imunogenicidade, pode causar efeitos adversos. Avanços tecnológicos possibilitaram  desenvolvimento das vacinas recombinantes Bexsero e Trumenba contra o meningococo B para induzir uma resposta imune segura. Este estudo teve como objetivo comparar as vacinas Bexsero e Trumenba e especular sobre o impacto de sua introdução no calendário vacinal do Brasil. Consistiu em uma revisão de literatura utilizando artigos coletados de base de dados publicados entre os anos de 1985 a 2023. Após a comparação foi demonstrado que a vacina Bexsero contêm múltiplos antígenos (proteínas recombinantes e antígenos de membrana externa), tendo uma grande abrangência de faixa etária e eficácia em crianças e adolescentes, enquanto a Trumenba utiliza duas variantes de fHbp, sendo indicada para jovens adultos e aplicada em surtos universitários. Após as análises no Reino Unido e sua inclusão em seu programa nacional de imunização, a vacina Bexsero surge como uma alternativa adequada para a inclusão no Programa Nacional de Imunização do Brasil (PNI) por apresentar cobertura mais ampla e melhor eficácia, reduzindo a incidência da doença meningocócica invasiva e suas complicações.
THE IMPORTANCE OF BUSINESS INCUBATORS FOR THE IMPLEMENTATION OFENERGY MANAGEMENT
Authors:   University of Novi Sad, Technical Faculty “Mihajlo Pupin”, Zrenjanin, Serbia, Milošev Vladimir , Dragović Rade ,   University of Novi Sad, Technical Faculty “Mihajlo Pupin”, Zrenjanin, Serbia, Kostovski Igor ,   University of Novi Sad, Technical Faculty “Mihajlo Pupin”, Zrenjanin, Serbia
Published: November 2024

This paper explains the key role of business incubators in advancing energy management initiatives in entrepreneurial ecosystems. It indicates that by providing basic resources, mentoring and networking opportunities, incubators empower startups to develop innovative solutions that improve energy efficiency and sustainability, and thus receive support that facilitates the creation of new business models and technologies that address pressing energy challenges. Through collaborative efforts, incubators foster partnerships among entrepreneurs, investors and industry experts, fostering the growth of sustainable practices. Ultimately, business incubators serve as vital catalysts for promoting efficient energy management strategies, contributing to a greener and more resilient economy.
Penerapan Metode Activity Based Costing dalam Menentukan Tarif Rawat Inap di Rumah Sakit Wava Husada Kepanjen Kabupaten Malang
Authors: Pradana Muhammad Zaki
Published: November 2024

One of the hospital's revenues comes from inpatient services, so the determination of inpatient rates is one of the important aspects that need to be considered. So far, many hospitals in Indonesia still use conventional methods in determining hospitalization rates, although these methods often cause inefficient rates. This study aims to examine the application of the Activity Based Costing (ABC) method in determining hospitalization rates at Wava Husada Hospital, identify the obstacles faced in the implementation of the method, and find solutions to overcome these obstacles. This research is a type of qualitative research. The type of data used in this study is secondary qualitative data obtained from respondents through interviews and observations. The data analysis technique used is descriptive analysis. The results of this study show that the hospitalization rate at Wava Husada Hospital based on the ABC method provides greater results in classes VIP B, VIP C, I A, I B, II A, and II B and III and gives lower results in class, and class VVIP A. The price difference occurs because the ABC method charges overhead costs on each product in more detail. The implication of the study is that the results of the implementation of the hospitalization rate of Wava Husada Hospital Kepanjen Malang Regency with the ABC method can be used as a reference for Wava Husada Hospital to determine the hospitalization rates of classes VVIP A, VIP B, VIP C, I A, I B, II A, II B, and III so that it can be more efficient and accurate.
Prediction of Shrimp Price Based on WOA-VMD-XGBoost Algorithm and SHAP Model
Authors: Wu Zhan , Qu Tinghong , Cha Sina , Wang Chunxiao , Zou Zongfeng
Published: November 2024

This research aims to construct a WOA-VMD-XGBoost-SHAP model to predict shrimp prices and analyze the nonlinear effects of key predictors. Firstly, the whale algorithm (WOA) is used to optimize the K-value and penalty parameter of the variational mode decomposition (VMD) to adaptively decompose the original price series and reduce the data noise. In addition, the trend, period, high and low frequency, and residual terms obtained from the decomposition of the original price series are used as inputs to the XGBoost model for training and testing. Finally, K-fold cross-validation and learning curves are used to test the model performance and analyze the nonlinear effects of key influencing factors in combination with the SHAP model. The results show that the Bayesian-optimized WOA-VMD-XGBoost model has excellent predictive performance with an R2 of 0.927, which is better than other benchmark models; the fluctuation of shrimp prices is cyclical, and the cyclical term accounts for 67% of the characteristic importance. The model can provide effective technical support and decision-making references for relevant management departments and enterprises to predict the price fluctuation of aquatic products.
Erken Cumhuriyet Dönemi (1923-1950) Eğitim Alanının Yapısı ve Dinamikleri'ne Eleştirel Bir Yaklaşım
Authors: Duran Selfet
Published: November 2024

Bu çalışma erken Cumhuriyet dönemi (1923-1950) eğitim alanının yapısal tarihini, bu dönemde eğitim alanında yaşanan değişim ve dönüşümleri, alanda eyleyiciler (agents) açısından mücadele nesnesi haline gelen bahisleri (illusio), eğitim alanındaki kültürel sermayenin niteliğini ve bu kültürel sermayeyi belirlemek üzerine verilen siyasal-toplumsal mücadeleleri ortaya koymayı amaçlamaktadır. Çalışmada Cumhuriyetin eğitim kurgusunun niteliği, eyleyicilerin bu kurguyu aşındırma denemeleri, günümüze kadar gelen, sınıfsal yeniden üretim, fırsat eşitliği, dini ve özel öğretim, siyasal endoktrinasyon gibi temel tartışma konularının tarihsel kökenleri ortaya konulmaya çalışılacaktır. Bunun için eğitim alanı içerisindeki eyleyicilere kültürel ve sınıfsal yeniden üretim ve ayrım/ayrışma fırsatları sunan ve kültürel ideolojik kodlarını eğitim kültürüne yansıtma olanağı veren ortaöğretim alt alanındaki okul türleri ve öğrenci sayılarının tarihsel süreç içerisindeki değişimine odaklanılacaktır. Literatür taraması yöntemiyle gerçekleştirilen çalışmanın kuramsal çerçevesini Bourdieu’cü yapısal tarih ve alan analizi tartışmaları oluşturacaktır. Bourdieu’cü yapısal tarih ve alan analizi daha önce kültürel-ideolojik çerçevede pek çok kez araştırması konusu yapılan Erken Cumhuriyet Dönemi eğitim alanındaki eyleyicilerin peşinde oldukları ve sınıfsal ve kültürel ayrım/ayrışma fırsatları sunan yeni bir kültürel sermaye türünün inşa sürecini ve bunun toplumsal-sınıfsal yapı üzerindeki etkilerini ortaya koymak açısından önem arz etmektedir. Bu çalışmanın en önemli iddiası ve özgünlüğü de budur.
Academic Expression of a Chinese Master's Nursing Student in Proposal Defense in the Philippines: A Qualitative Analysis and Improvement Suggestions of a Case Study
Authors:   PhD Candidate in Educational Management majoring in English, Graduate School, Emilio Aguinaldo College, Lyu Hongying
Published: November 2024

This case study explores the academic expression challenges faced by a Chinese nursing master's student during the thesis proposal defense in the Philippines. By analyzing recorded transcripts of the defense Q&A segment and panel feedback documents, the st udy identifies specific issues in academic expression, including vague definitions, unclear research objectives, and deficiencies in theoretical frameworks and research designs. The feedback from professors emphasizes the importance of a systematic researc h design, clarity in academic terminology, and adherence to academic writing standards. The study offers targeted suggestions for the student to enhance academic expression, such as improving content organization, enriching theoretical frameworks, refining data collection methodologies, and integrating diverse academic sources. Additionally, it provides universal recommendations for all international students facing similar challenges, including the significance of seeking continuous fe edback, engaging in s elf reflection, and developing effective academic communication skills. Overall, this research aims to provide valuable insights and strategies for international nursing students to navigate academic expression challenges in cross cultural contexts effecti vely.
Ukraine's Strategy to Counter Russian Cyber Threats in the Russo–Ukrainian War
Authors:   Universitas Kristen Indonesia, Sarimin Billy Jeremie , Damayanti Angel ,   Universitas Kristen Indonesia
Published: November 2024

This study investigates the cyber threats that Russia poses to Ukraine and examines the strategies that Ukraine employs in response. The Russian cyber operations are believed to have started covertly before the beginning of the Russia-Ukraine War in 2022. These operations peaked when Russia targeted the Kyiv Post news agency and the KA-SAT satellite, resulting in significant communication disruptions and power outages within Ukraine, which affected both the government and society. The research utilizes theories of security strategy, cyber threats, and cybersecurity strategy to analyze the cyber tactics used during the Russia-Ukraine conflict. Employing qualitative methods and case study models, the study describes Russia's cyber operations that threaten Ukraine’s security, as well as Ukraine's responses to these threats. The operations included information manipulation and attacks on critical infrastructure. Findings reveal that the Ukrainian government implemented several effective strategies, such as establishing legal frameworks, creating cybersecurity agencies, and collaborating with the United States. These measures have proven successful in countering Russian cyber-attacks. Through its partnership with the U.S., Ukraine’s rapid response team (CERT) was able to recover systems that had been targeted, thereby enhancing Ukraine’s cyber resilience against Russian threats.
ЖАРАТЫЛЫСТАНУ БАҒЫТЫНДАҒЫ МЕКТЕПТЕРДЕГІ ӘДЕБИЕТТІ ОҚЫТУДЫҢ ТӘЖІРИБЕСІ МЕН ИННОВАЦИЯЛАРЫ
Authors: Куатова Индира , Керимбекова Баян , Еркінгүл Солтанаева
Published: November 2024

In this article, the authors pay attention to the peculiarities of teaching literature in natural science schools, its experience and innovative methods. It allows to enrich the educational process and develop students' creative abilities by analyzing the role of literature and effective ways of learning in an environment where priority is given to natural sciences.
“I THINK TEACHERS MUST SPEAK ONLY ENGLISH”: EXPLORING LECTURERS' PROFESSIONAL ATTRIBUTES AND PRACTICES TO FACILITATE EMI PROVISION IN HIGHER EDUCATION
Authors: Gaipov Davronzhon , Tulepova Saule , Bekturova Madina
Published: November 2024

This study aims to investigate the students’ and teachers’ perceptions regarding English as a Medium of Instruction (EMI) lecturers’ attributes and practices that facilitate EMI provision at higher education institutions in Kazakhstan. By adopting the “Good-enough-to-teach” model of the EMI lecturer by Lavelle, the research explores the adequacy of qualified EMI lecturers and their practices in delivering EMI classes. The data is derived from surveys administered to 1506 students and 157 teachers. Key findings highlight the importance of lecturers' knowledge of the subject matter and English, sensitivity to students' needs and culture, and the ability to explain concepts in English clearly. These findings have significant implications for implementing and improving EMI programs in Kazakhstani higher education as well as in other non-Anglophone contexts, particularly in understanding the key attributes of qualified EMI lecturers. Specifically, it is believed that the results would help in developing clear guidelines and policies for universities to recruit qualified staff who can effectively achieve the goals and objectives of English-taught educational programs.  The study also would raise the awareness of the educational stakeholders regarding the desired qualities of skilled EMI lecturers.
Le temps du travail et le travail du temps
Authors: Izoard-Allaux Sophie
Published: November 2024

Le climat général de cette décennie montre que la situation dans le rapport de soi au travail et dans les relations de travail est souvent dégradée. L’écart entre volonté de maîtrise technique et interrogation du mystère de l’être n’est plus assumé, tandis que l’individualisme n’est plus un facteur de résistance, s’alignant sur un conformisme tranquille. Comment dès lors réinventer une nouvelle feuille de route autour du travail, qui puisse réellement nourrir les conditions de la vie bonne et corriger la relation déréglée, voire pathologique, du sujet au travail, dans son rapport subjectif à soi et au monde ? Une des réponses possibles pourrait passer par la convocation des notions de temporalité, créativité et écologie dont l’entrelacement serait promesse d’un nouveau récit autour du travail, fondé sur le soin de soi, des autres et de la terre.
Membangun Penguasaan Konsep Siswa SD Kelas 3 Pada Materi Perubahan Sifat Benda Melalui Pendekatan STEM
Authors: Nihayatul Qudsiyyah Ulin , Srinana Wardani Imas , Hermin Rusminati Susi
Published: November 2024

Penelitian ini didasarkan pada kenyataan bahwa siswa kelas III SD masih memiliki penguasaan konsep yang kurang. Penguasaan konsep sangat penting karena memungkinkan siswa untuk menyerap, memahami, dan mengingat materi yang dipelajari dalam jangka waktu yang lama. Dengan penguasaan konsep yang baik, siswa diharapkan dapat mendeskripsikan dan menghubungkan berbagai konsep satu sama lain. Penelitian ini bertujuan untuk mengetahui pengaruh pendekatan STEM dalam membangun penguasaan konsep pada materi perubahan sifat benda. Penelitian ini menggunakan rancangan penelitian kuantitatif Quasi Experimental Design melalui Pre-test Post-test Nonequivalent Control Group Design. Populasi penelitian ini mencakup seluruh siswa di SDN Bangsri, sementara sampel yang digunakan dalam penelitian ini adalah siswa dari kelas III-A (kelas kontrol) sebanyak 20 siswa dan kelas III-B (kelas eksperimen) sebanyak 20 siswa. Teknik pengumpulan data menggunakan teknik tes yang berjumlah 10 soal essay keterampilan berpikir kreatif. Hasil dari penelitian ini adalah nilai sig. (2-tailed) sebesar 0,000 < 0,05, yang artinya H0 ditolak dan H1 diterima, yang berarti terdapat pengaruh pendekatan STEM dalam menumbuhkan penguasaan konsep siswa kelas III SD pada materi perubahan sifat benda
Kata Kunci: STEM, penguasaan konsep, perubahan sifat benda
Optimalisasi Media Digital Dalam Pembelajaran Ekonomi
Authors: Muh. Syata Wahyu , Mardhatillah Sabillah Bellona , Damayanti  , Subur Hikmayani , Juwantho Lewa Muhammad
Published: November 2024

Learning media are all types of physical equipment that aim to convey information and create interaction. Media used in learning, such as print and text media, audio media, moving images, multimedia media, and web-based or internet media. This research uses literature review research. In learning economics, optimizing digital media can help students improve their critical and creative thinking skills and increase their ability to learn. Various learning settings can be done using digital media, moving from individual to collaborative between students and students and students and teachers. Digital media in learning is very helpful for teachers and students in the learning process, it makes learning younger, makes the material easier to understand, makes the learning process more efficient, and achieves learning objectives. Teachers also act as facilitators, motivators and role models for their students, encouraging them to work harder in the classroom and utilize the ever-evolving technological media to access information sources relevant to economic learning objectives. By applying digital media in learning economics, students are able to broaden their understanding of economics that covers a wide range of contexts both theory and practice and know the relationship between events that occur in economics
The Correlation Analysis Between Students Performance and Licensure Examination Result of Beed Graduates in Um Panabo College
Authors: Muico, PhD Jeanilyn E. Tacadena- , Chan, PhD Liezel V. , Camacho, MAEd Albert
Published: November 2024

This study used descriptive correlational research designs to determine the relationship between student’s performance and licensing examination outcomes. Using random sampling forty (40) participants were identified in the study; these are the graduates of the BEED Program who took the Licensure Examination for Teachers (LET) from 2018-2021.The Pearson r correlation was used to establish the significant link between the Competency Appraisal (CA) result, General Weighted Average (GWA) and On-the-Job-Training (OJT) rating and the board examination rating. Data from the CA result was taken from the Competency Appraisal Coordinator, while GWA and OJT rating is taken from the registrar office, further PRC issued the result of the LET. The results shows that the competency appraisal has no significant relationship with the result of the board examination. On the other hand, the GWA and the OJT grade of the BEED graduates significantly correlated with the PRC result, suggesting it helps the students pass the licensure exam. Students who perform well in their college courses, particularly in courses that are directly related to their profession, are more likely to have a strong foundation of knowledge and skills that are necessary to pass the LET. Thus, the researcher recommends to look for other possible factors, such as students’ personal, economic, and emotional factors, students’ performance from their respective review centers.
Motherhood or Womanhood? A Closer Analysis of Buchi Emecheta’s the Joys of Motherhood
Authors: Kamankura Nelly Gatuti , Gikunda Njogu Dr. Jackson
Published: November 2024

Literary research on women has been done by various scholars; often depicting stereotypical imaginations of how a woman should behave, who should determine her worth in the society and even on the patriarchal notions on womanhood. Scholars have also concentrated on portrayal of women in male writings. However, studies on womanhood still remains an area of interest. This paper explores the concept of womanhood in African literature by focusing on what defines a woman in Africa, historical development of womanhood in Africa, the humanistic approach to women as beings with feelings and the cultural expectations of women and how they navigate through them. Through the use of black feminism theory, this paper explores Emecheta’s The Joys of Motherhood to explore contrasting aspects of womanhood as portrayed through Nnu Ego and Adaku. The findings reveal that Adaku represents the contemporary woman whose life and beliefs are not tied to traditions that dictate how she should live her life; also, the Nnu Ego’s adherence to tradition and its dictates is revealed, for instance how she remains in Nnaife’s house despite how he mistreats her, because that is what is expected of her by the Igbo traditions.
Exploring the Perspectives of Ghanaian Youth on the Sustainable Development Goals: Awareness, Attitudes, and Practice
Authors: Danso Alex , Owusuaa Erica
Published: November 2024

The United Nations recognizes the youths of today as essential stakeholders and vehicles through which the SDGs can be achieved. This is because the young people of today are going to be the leaders, innovators, and change-makers of tomorrow. The knowledge and practice of the youth towards the SDGs is thus essential if we can achieve the SDGs. This study therefore examined the perspective of the youths in Ghana concerning the SDGs. Quantitative and explanatory research approaches were employed to gather and analyze data. The study administered a questionnaire through an online survey to 384 youths in the Ashanti region of Ghana. Descriptive and inferential statistics were used to analyze the data with the aid of SPSS. The study found that there is a statistically significant relationship among awareness, attitude, and practices of the youths related to sustainable development. While there was a generally high level of awareness and a positive attitude, turning these into consistent sustainable practices remains an uphill task. The results show that Ghanaian youths have a positive attitude towards the SDGs, but in real life, convenience, cost, and lifestyle hinder them from fully acting on sustainability. The study therefore recommends that the government and other stakeholders implement robust educational campaigns that not only raise awareness but also instill in the youth the importance of making life changes and adopting sustainable behaviors. The government should provide incentives and subsidies to encourage businesses to produce green products which can make sustainable choices more convenient and accessible to the youths in Ghana. The government should also ensure strict environmental regulations. These measures can help in bridging the gap between knowledge and practice, ultimately fostering an environmentally conscious and sustainable society.