bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPROVING ENVIRONMENTAL SANITATION KNOWLEDGE OF SUGARCANE PROCESSING FARMERS GROUP IN NAGARI BATUBULEK, TANAH DATAR REGENCY
Authors: Ramli Ramli , Desnita Desnita , Darvina Yenni , Mawardi Mawardi
Published: September 2023

Nagari Batubulek is one of the sugarcane plantation areas in Tanah Datar regency, West Sumatra province, Indonesia. In nagari Batubulek itself, the “Marapalam Indah” farmer group processes sugar cane using a pressing machine and has 10 stoves to cook the cane into cane sugar. Every day this farmer group processes 750 kg of sugarcane into approximately 75 kg of cane sugar and 250 kg of bagasse. Currently, the bagasse produced is burned, as a result the smoke from the burning disturbs workers and pollutes the surrounding environment. Based on the results of interviews with the heads of farmer groups and several visits to the location of the kitchen for making sugar cane, it was found that the partner's problem was that farmers' knowledge in environmental sanitation were still low. The solution offered is to increase the knowledge and skills of partner communities to process bagasse into useful materials and to improve the sanitation of a clean kitchen environment through ongoing training and assistance. After the training and counseling, it was seen that the knowledge of environmental sanitation from the farmer groups had increased.
NATIONAL DENTAL HEALTH MONTH PROGRAM 2022 SCHOOL HEALTH PROGRAM WITH ITS KINDERGARTEN
Authors: Revianti Syamsulina , Brahmanta Arya , Agnita Cevanti Twi , Puspita Sinta , Khoironi Emy , Pangabdian Fani , Widaningsih Widaningsih , Hanum Faizah , Listya Paramita Annisa , Dwi Maharani Aulia , Paramita Ayulistya , Iman Dimas , Rizal Mohammad Basroni , Anindya Pinasti Restika , Soesilo Diana
Published: September 2023

Dental and oral health in Indonesia is still a health problem that needs attention. The most concerning thing is that as many as 93% of school-age children experience dental and mouth problems. This can be caused by a lack of knowledge and awareness of dental hygiene. One of the efforts made to increase knowledge and awareness of dental hygiene is by holding an educational activity called the "School Health Program". This activity was carried out in several schools, one of which was TK ITS. This activity began with the Training of Trainer Program given by dentists to teacher cadres and parents of students/students/students about the benefits of good oral hygiene and how to brush your teeth twice a day with fluoride toothpaste. Dentists provide educational materials using power point media and educational videos through the zoom application. There were 5 cadres consisting of 2 teachers and 3 guardians of students who attended this activity. After that, the teacher cadres and parents of the students/students disseminate information to other parents of students/students so that they can become mentors to their children to apply good and correct behavior of brushing their teeth twice a day for 21 days with the method recorded on the given calendar. The hope is that after this program ends, students at ITS Kindergarten have the behavior of maintaining oral hygiene by brushing their teeth twice a day with fluoride toothpaste.
CULTIVATION OF HENNA WATER PLANTS AS AN ECONOMIC VALUE COMMODITY IN GETAKAN VILLAGE, KLUNGKUNG REGENCY
Authors: Lestara Permana Gusi Putu , Sastra Dewanti Wayan Ari , Wirya Darma I Made , Wahyudi Oktavia Gama Adie , Suparna Putu , Adhiya Garini Putri Dewa Ayu , Kalfika Anggria Wardani Kadek Devi , Sutama I Wayan
Published: September 2023

The farming program in the village is 70% dependent on rice and cloves. which has approximately a harvest time interval of three to one year, while the percentage of girlfriend water flowers (Impatiens balsamina)  cultivation in the village of Getakan is still 30%, therefore activities are more focused on raising the cultivation of water henna plants,  so that farmers have additional income every day. However, currently there are problems, in terms of reduced flower production, lack of pest management using pesticides, minimal flower quality improvement, lack of knowledge about social media as a means of promotion, and stages of online education. This study aims to provide education regarding steps, tips, and also information related to the application of girlfriend water flowers (Impatiens balsamina) cultivation and promotion on social media as well as increasing knowledge and also developing community farming related to optimizing the potential of paddy fields by cultivating commodities that can be used to produce and make a product as additional income for rural communities. The results obtained by the people of Getakan Village can produce good and quality girlfriend water flowers (Impatiens balsamina) so that they increase their daily income.
EFFECTIVE MARKETING TRAINING FOR MSMES WITH THE CONCEPT OF TECHNOPRENEUR
Authors: Wirasmara Kusuma Hero , Azizi Enji
Published: September 2023

Even though the number of MSMEs in Indonesia continues to increase while bringing many positive effects in the form of employment which can reduce unemployment and others, problems with MSMEs or Micro, Small, and Medium Enterprises do often occur. The problem that most often occurs lies in marketing, which turns out to be a lot of people who don't understand online marketing. Even though many MSME actors market their products through marketplace sites, social media accounts, and so on, they are not optimal and consistent in practice. Therefore, we introduce the concept of Marketing 4.0 which redefines marketing from Marketing 3.0, namely marketing must adapt to the changing nature of the customer path in the digital economy, where the role of marketers is to guide customers along their journey from awareness and finally to advocacy. It is the concept that we are trying to socialize to MSMEs in carrying out effective marketing techniques for their businesses, of course with the technopreneur concept which they have been used to doing so far. In this training, marketing strategies for MSME products, as well as MSME marketing strategies, are explained, from the marketing strategies commonly used in the form of; creating unique products, marketing products by becoming a networker, determining STP, and taking advantage of e-commerce. Next, we describe a marketing strategy that 1. embraces the shift to a more horizontal, inclusive, and social business landscape, 2. explains the changing landscape creates a series of paradoxes that marketers have to face, one of which is online versus offline interaction, 3. Understands that young people are sharing thoughts, women for market share, and netizens for sharing hearts, 5. Inviting MSME businesses to redefine marketing in the digital economy, as well as develop a new framework for marketing in the digital economy.
STRATEGY EDUCATION TO INCREASE BANK BPD BALI'S ASSET GROWTH THROUGH ITS ABILITY AS AN AGENT OF REGIONAL DEVELOPMENT
Authors: Amarani Aura , Wirsa I Nengah
Published: September 2023

Global economic growth is anticipated to slow in 2023 from 2022, accompanied by rising inflationary pressures, aggressive monetary policy rate hikes, and financial market uncertainty. This growth must be independent of the bank's role as an economic body that supervises, accumulates, and distributes monies to the public through deposits. Regional Development Bank (BPD) is a banking entity created by a local government with total shareholders or a fraction of shares controlled by the local government. The challenge is that the growth rate of commercial bank assets in Bali is larger than BPD Bali Bank. One of the actions that may be done is to carry out a strategy to create capacity as an agent of regional development. Briefing and learning activities allow organizations to become more aware of the importance of implementing ways to improve the growth of company assets. This activity is planned to follow up the implementation of the capability-building strategy as an agent of regional development in increasing the growth of Bank BPD Bali's assets so that asset growth increases optimally.
Scoping Review: Diarrhea in Toddlers and Causing Factors
Authors: Susilowati Endang , Astuti Yuli , Mulyasih Refi
Published: September 2023

Diarrhea is a disease caused by infection with microorganisms including bacteria, viruses, parasites, and protozoa, and its transmission is fecal-oral. Diarrhea is a condition where stool is excreted abnormally or not as usual, characterized by an increase in volume, dilution, and frequency of bowel movements more than 3 times a day and in neonates more than 4 times a day with or without blood mucus. Diarrheal disease is still a public health problem in developing countries such as Indonesia, with high morbidity and mortality. From the IDHS results, it was found that 13.7% of children under five experienced diarrhea in the two weeks before the survey, 3% higher than the IDHS findings. The highest prevalence of diarrhea is in children aged 12-23 months, followed by those aged 6-11 months and those aged 23-45 months. (Ministry of Health, 2011). Research objective: This study aims to analyze the factors that influence the incidence of diarrhea in toddlers, based on the results of previous studies. Method: This research was conducted using the scoping review method using several data-based electronic media: Pubmed, DOAJ, Scopus, Sinta, and limited database, namely the last 10 years starting 2012-2021. There were 20 articles used which discussed the causes of diarrhea in toddlers. Results: Factors causing diarrhea that were intensified include the mother's knowledge about hygiene and environmental hygiene, unsanitary water sources, latrines in the family, and health services that are difficult to reach, giving complementary foods too early, and germ infection factors, toddler nutrition factors low and mother's knowledge of diarrhea in toddlers, posyandu visits, non-exclusive breastfeeding and use of milk bottles and hygiene, number of family members and low economic status.
Operational Managing Analysis in Driving Product Marketing to a Global Scale (Case Study PT Indofood CBP)
Authors: Suhairi Suhairi , Nararya Habib Lauda , Tri Wardani Silvi , Wardani Tria , Mutiara Ayu Indah
Published: September 2023

The operational activities of the company have a major urgency in management to the level of production carried out. The operational system as well as the right management can affect the long-term sustainability of the company. In a global market share, it is necessary to have the role of operational management to improve marketing patterns as well as the expected gains. This process is seen in terms of planning, organizing, implementing up to the monitoring stage. This study aims to analyze the operational managing program used to encourage the marketing activities of a product to reach a global scale by PT Indofood CBP. The research method used is a qualitative research method using a descriptive type approach. The main data source used is information that supports the structure or operational husk of PT Indofood CBP itself and is supported by secondary data sources in the form of literature relevant to the research topic. The collection technique used was a literature study. The research results show that.
Preparation of Population Data Base for Community Unit 11 East Pamulang Village, Pamulang District South Tangerang City
Authors: Rusdiyanto Edi , Naili Muna Siti Umamah , Sumartono Sumartono , Munawir Abdillah
Published: September 2023

Village and sub-district administration, neighborhood unit functions to record population data and other government administration services, maintain security, support, and inter-living harmony, generate ideas in the implementation of development by developing the aspirations and genuine self-help of the community, and activating self-help cooperation and participation of the community members in their area. So that the purpose of implementing AbdiMas is to increase understanding of simple technology in processing population databases in neighborhood units and Community Unit 11 East Pamulang Village administrators. The method used is Active and Participatory Learning with material discussions, practices, and demonstrations. The results of the training and database input based on all available information provide a very simple understanding of technological knowledge using Microsoft Office Excel and add broad insight to local neighborhood units and Community Unit 11 administrators on the importance of inputting databases to facilitate all the interests and aspirations of the community for the implementation of village government as well as the village. Overall, 90% of the neighborhood and Community Unit 11 administrators understand the use and input of databases using Microsoft Excel, making it easier to formulate policies related to education, health, economy, and social affairs, the government of East Pamulang Village, South Tangerang City.
Analysis of Implementation of Margins with Flat Installments in Murabahah Financing on Products iB PMG Motor Vehicles in the Bank of Sumut Sharia KCP HM Yamin
Authors: Kinanti Susi , Samri Juliati Nasution Yenni , Irham Mawaddah
Published: September 2023

This study aims to determine the mechanism for implementing margins with flat installments in murabahah contracts and the factors that influence them on motor vehicles ib PMG products at Bank Sumut Syariah KCP HM Yamin. This study uses a descriptive qualitative approach with primary and secondary data sources. This study used data collection techniques by interviewing. The results of the research are that the mechanism for implementing margins on flat installments on murabahah contracts for iB PMG Motorized Vehicle products at Bank Sumut Syariah begins with the analysis of the treasure division by considering various costs and all that affect the financial value of Bank Sumut Syariah which is then discussed together with the DPS of the Bank. Sumut Syariah will then be presented at a joint meeting with Bank Sumut Syariah officials to agree on the provisions that have been analyzed and proposed by the treasure division. The size of Bank Sumut Syariah's margin is influenced by cost factors related to Overhead Costs, Profit Sharing of Third Party Funds (DPK), and Volume of Murabahah Financing. This study aims to determine the mechanism for implementing margins with flat installments in murabahah contracts and the factors that influence them on motor vehicles ib PMG products at Bank Sumut Syariah KCP HM Yamin. This study uses a descriptive qualitative approach with primary and secondary data sources. This study used data collection techniques by interviewing.
Cómo han evolucionado los sistemas de salud modernos
Authors:   Universidad de Guadalajara, López Delgadillo Jaime
Published: September 2023

Cómo han evolucionado los sistemas de salud modernos
El proyecto nacional
Authors:   Universidad Nacional Autónoma de México, Martínez Ifigenia
Published: September 2023

El proyecto nacional
Teoría económica y estrategia de empresa: conflictos y aportaciones
Authors:   Universidad de Guadalajara, Fong Reynoso Carlos
Published: September 2023

Teoría económica y estrategia de empresa: conflictos y aportaciones
Tide gauge metadata catalogue
Authors: Westbrook Guy
Published: September 2023

Tide gauge metadata catalogue V1.0 (EU-TGN or European and adjacent areas Tide Gauge Network Inventory); accuracy and precision review of the EuroGOOS Tide Gauge Task Team (TGTT) database of permanent monitoring nodes for European and adjacent coastlines. A metadata catalogue of all permanent, managed tide level monitoring stations across Europe and adjacent coastlines, including North Africa.
Euro-Argo updated strategy
Authors: Gourcuff Claire
Published: September 2023

Euro-Argo strategy in the context of the OneArgo new international design
Sürdürülebilir Kalkınmada Beslenme ve Besinin Gerçek Fiyatı
Authors: Haydaroğlu Mehmet , Bilgiç Pelin
Published: September 2023

Sürdürülebilirlik küresel kalkınmada temel strateji olup bu doğrultuda besin sistemlerinin dönüşümü gerekmektedir. Besin sistemi sadece besinin nasıl elde edildiğini değil, besinin ilişkili olduğu tüm süreçlerin ve unsurların yanı sıra ortaya çıkardığı sonuçları da kapsamakta olup sürdürülebilirliği hedeflenmektedir. Besin sistemlerinin sürdürülebilir olması; ekonomik, sosyal ve çevresel temellere dayanması ve herkese besin güvencesi imkânı sağlayabilmesine bağlıdır. Mevcut besin sisteminde gizli maliyetlerin dikkate alınmaması besin sistemlerinin sürdürülebilirliğini etkilemektedir. Besinin piyasa değerine yansıtılmayan bu maliyetler dışsallaştırmaları ifade etmektedir. Çevresel, sağlık, sosyal ve ekonomik olarak kategorize edilebilen bu dışsallaştırmalar negatif de olsa pozitif de olsa sonuçta bir kesimin tercihleri ve bunların sonuçları başkalarını hatta sonraki nesilleri etkilemektedir. Besinin gerçek maliyeti yaklaşımı, dışsallaştırmalardan gelen gizli maliyetlerin değerlendirilerek pazar değerine yansıtılmasını sonuçta besinin gerçek fiyatını hedeflemektedir. Mevcut ekonomiler tüketicilerin besinleri gizli maliyetleri dâhil olmadan iki hatta üç kata kadar daha ucuz alabildiği fakat farkında olmadan başta vergilerle olmak üzere bu maliyetleri kendisinin ödediği düzene dayanmaktadır. Besinin fiyatı gerçek değerini yansıtmamakta olup toplumda farkındalığın oluşmasını engellemekte, sürdürülebilir olmayan, sağlıksız ve satın alınabilirliği düşük besinlerin üretimini teşvik etmektedir. Fakat hem gerçek maliyet muhasebesinde dışsallaştırmaların değerlendirilmesinde problemler hem de bu maliyetle belirlenecek besinin gerçek fiyatının tüketici ve üretici açısından potansiyel riskleri mevcuttur. Bu derlemede sürdürülebilir kalkınmada beslenme ve besin sistemlerinin rolüyle beraber besin sisteminin dönüşümünde besinin gerçek maliyeti ve fiyatı teorilerinin açıklanması amaçlanmaktadır.
Besin Güvencesizliği ve Mental Sağlık İlişkisi
Authors: Şahin Kezban , Akbulut Gamze
Published: September 2023

Besin güvencesi; besinlerin mevcudiyetini ve karşılanabilirliğini içeren, besinleri kabul edilebilir yollarla elde etmeyi, bireysel besin kullanımının yanı sıra kültürel normları da kapsayan karmaşık bir olgudur. Küresel besin üretimindeki ilerlemelere rağmen, dünya genelinde yaklaşık 928 milyon insan besin güvencesinden yoksun durumdadır. Besin güvencesizliği; malnütrisyon, anemi, obezite, diyabet, hipertansiyon gibi birçok beslenme ve fiziksel sağlık problemi ile ilişkilidir. Bununla birlikte besin güvencesizliği farklı boyutları aracılığıyla mental sağlık ile de yakından ilişkili görünmektedir. Sosyoekonomik durum, cinsiyet, etnik köken vb. besin güvencesini etkileyen faktörler göz önünde bulundurulduğunda besin güvencesizliğinin olumsuz fiziksel ve mental sağlık sonuçları ile ilişkili olması şaşırtıcı bir durum değildir. Literatürde besin güvencesizliği ve mental sağlık ilişkisini değerlendiren çalışmalar sınırlı olmakla birlikte yapılan araştırmaların sonuçları çelişkilidir. Bu çalışmanın amacı, güncel literatür doğrultusunda besin güvencesizliği ile mental sağlık sorunları arasındaki ilişkiyi incelemektir.
Yarı-biyonik İnsan: Yapay Kalp ve Yapay Pankreas Taşıyan Hastada Beslenme Tedavisi ve İzlemi
Authors: Şahiner Elif , Yılmaz Mehmet Temel , Kızıl Mevlüde
Published: September 2023

Diyabet, göreceli ya da mutlak insülin eksikliği veya periferik dokularda meydana gelen ’insülin direnci’ nedeniyle ortaya çıkan, hiperglisemi ile karakterize kronik metabolik bir hastalıktır. Hastalığa bağlı komplikasyonlar artmış morbidite ile ilişkilidir. Komplikasyonların önlenmesinde kan glukoz düzeyinin fizyolojik değerlere yakın seyretmesi amaçlanmaktadır. Tıbbi beslenme tedavisi ve fizyolojiye yakın insülin replasmanı glisemik kontrolün sağlanması ve diyabete bağlı komplikasyonların önlenmesinde önemli bir etmendir. İnsülin pompaları, sürekli insülin infüzyonu sağlayarak fizyolojik insülin salınımını yaklaşık olarak taklit eden mekanik cihazlardır. Sensör entegreli insülin pompası ise düşük glukoz seviyelerini tespit etmek ve öngörebilmek için sensörden elde edilen verileri kullanır; glukoz seviyesi düşmeden önce insülin iletimini otomatik olarak durdurur ve yeniden yükselmeye başladığı zaman iletimi yeniden başlatır. Sonuçta kan glukoz düzeyi regülasyona olumlu katkı sağlar.
Bu olgu sunumunda; kalp yetmezliği nedeniyle yapay kalp (Thoratec HeartMate III Left Ventricular Assist System) taşıyan olgunun tip 2 diyabet tedavisi için kablosuz insülin pompası (yapay pankreas) (Medtrum A7 + TouchCare Kablosuz İnsülin Pompası) takılmasıyla birlikte uygulanan beslenme eğitiminin hastanın vücut ağırlığı, kan lipit düzeyleri, HbA1c ve kullanılan toplam insülin dozu üzerine etkisinin değerlendirilmesi amaçlanmıştır.
Olguya üç aylık süreyle beslenme eğitimi ve tıbbi beslenme tedavisi verilmiştir. Bu uygulama sonrasında vücut ağırlığı, beden kütle indeksi, toplam insülin dozu, glikozillenmiş hemoglobin (HbA1c), toplam kolesterol, düşük dansiteli lipoprotein (LDL) kolesterol ve trigliserit değerlerinde düşüş sağlanmıştır. Tıbbi beslenme tedavisi diyabet tedavisinin ilk basamağıdır, diğer tüm tedaviler bu tedavinin üstüne eklenmelidir.
Polycythemia Vera: A Malignancy in Hematology: Review Article
Authors: Roliskana Shafalyn , Rahmadhona Devi
Published: September 2023

ABSTRACT: Myeloid neoplasm is a condition in which myeloid cells can undergo excessive clonal proliferation. One classification of the disease is polycythemia vera.Polycythemia Vera (PV) is a condition where there is an increase in the number of red blood cells reaching 125% of the calculation based on body mass and sex. PV is caused by mutations in the JAK2 gene. PV disease diagnosisBased on the results of the history, physical examination and supporting examinations in the form of laboratory tests. PV disease can be managed with phlebotomy, administration of aspirin, and cytoreductive drugs. Patients with PV can survive more than 10 years if treated quickly and appropriately.
Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease Patients: A Scoping Review
Authors: Safei Imran , Zulfahmidah Zulfahmidah
Published: September 2023

Introduction: COPD is a leading cause of chronic disease and death globally, with high mortality rates for those hospitalized or requiring mechanical ventilation. Delaying disease progression and improving patient outcomes can reduce healthcare costs and societal impact. Respiratory muscles play a crucial role in COPD, and specific endurance respiratory exercises have been shown to improve muscle fibers and mitochondrial activity, reducing oxidative stress and fatigue. Inspiratory Muscle Training (IMT) is a recommended pulmonary rehabilitation technique that enhances lung capacity and improves exercise performance by altering muscle fiber types and distribution. The impact of IMT implemented in COPD remains unclear. This scoping review aims to ascertain the impact IMT has on COPD patients.

Methods: A scoping review was performed in PubMed, Academic Search Complete/EBCSCO, and Grey Literature sources, including Google Scholar. IMT studies evaluating interventions for COPD patients that were published in 2018-2023 were included.

Results: We reviewed 644 studies, nine IMT interventions met inclusion criteria and were included in the current study. In the majority of studies, improvements were noted through the implementation of IMT interventions. Several facilitators and barriers were noted during implementation and contributed to the success or failure of the intervention.

Conclusion: Overall, IMT had conflicting effects on a variety of COPD patient outcomes. Numerous studies demonstrate, however, that IMT can improve COPD-related outcomes, such as respiratory muscle function, dyspnea symptoms, quality of life, autonomic function, exercise tolerance, diaphragmatic strength and reduced exertional dyspnea, and balance.
Strategi Pengembangan Agrowisata Berbasis Tanaman Hias Di Desa Bokor
Authors: Sitawati Sitawati , Suryanto Agus , Nurlaelih Euis Elih , Permanasari Paramyta Nila , Wicaksono Karuniawan Puji , Baskara Medha , Damaiyanti Dewi Ratih Rizki
Published: September 2023

Desa Bokor memiliki potensi sebagai Desa Wisata berbasis pertanian dan bentang alam serta letak yang strategis pada jalur wisata. Pada pengabdian masyarakat sebelumnya sudah dilakukan peningkatan ketrampilan perbanyakan tanaman hias dan analisis TWIN dalam pengembangan Desa Wisata di Desa Bokor. Sehingga, dalam mendukung program desa sebagai Desa Wisata diperlukan lomba kreativitas dan edukasi edukasi tanaman hias untuk meningkatkan keindahan dan kualitas lingkungan Desa Bokor. Tujuan kegiatan Pengabdian Masyarakat adalah: 1) Memanfaatkan lahan kosong atau tegal kosong dan pekarangan untuk budidaya tanaman hias, 2) Meningkatkan kualitas lingkungan desa dan meningkatkan keindahan desa, dan 3) Menggiatkan dan memotivasi warga desa untuk mewujudkan Desa Wisata. Masyarakat mengetahui dan memahami teknologi budidaya tanaman hias, manfaat, dan luaran pada kegiatan ini adalah: a) Masyarakat mengetahui dan memahami teknologi budidaya tanaman hias, b) Masyarakat dapat mengoptimalkan lahan pekarangan untuk tempat budidaya tanaman hias, dan c) Masyarakat desa menjadi termotivasi untuk mewujudkan desa agrowisata.
SMARCB1-Deficient Sinonasal Carcinoma–A Case Report and Literature Review
Authors: Kim Taegyeong , Hong Won-Gi , Cho Kyung-Ja , Yu Myeong Sang
Published: September 2023

Switch/sucrose non-fermentable-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1)-deficient sinonasal carcinoma is a rare subtype of sinonasal undifferentiated carcinoma (SNUC). Due to the highly aggressive nature of the disease course, it is important to diagnose early and use multimodal treatments in the course of the disease. Two main morphologic patterns are commonly identified under the microscope: plasmacytoid/rhabdoid and basaloid. Furthermore, it demonstrates a total absence of integrase interactor 1 expression upon immunohistochemical staining. Here, we present two cases of SMARCB1-deficient sinonasal carcinoma with contrasting outcomes.
A Feasible Sound Field Measurement in ENT Clinics for Contralateral Routing of Signals Hearing Aids: A Pilot Study
Authors: Han Jae Sang , Kim Yeonji , Hwang Eul Seung , Lim Ji Hyung , Park So Yong , Park Jeong Hae , Seo Jae-Hyun , Park Shi Nae
Published: September 2023

Background and Objectives The hearing in noise test (HINT) or sound localization test (SLT) is used as the standardized assessment for contralateral routing of signals (CROS) and bilateral microphones with contralateral routing of signals (BiCROS) hearing aids (HAs). However, implementing HINT or SLT can be challenging in most ENT clinics. In this study, we propose a new feasible method specifically designed for conducting a sound field hearing test for CROS and BiCROS HA users.Subjects and Method CROS/BiCROS HA users who visited Seoul St. Mary’s hospital between 2019 and 2021 were enrolled for the study. SLT was conducted in a sound-proof room equipped with two speakers positioned at a 45° angle from the patient on each side: noise stimuli were presented to the better ear the headphone patient was wearing while signals were presented to the worse ear via the speakers in the room. To validate the sound field test, a correlation analysis was conducted using the Bern benefit in single-sided deafness and the Korean version of the International Outcome Inventory for Hearing Aids (K-IOI-HA) Questionnaires.Results The aided speech discrimination score was significantly higher in the signal 60 dB HL/masking 50 dB HL condition than 50 dB HL/masking 50 dB HL condition (p<0.05). A significant correlation was found between the gain of sound field speech audiometry and the K-IOI-HA questionnaire (p<0.05).Conclusion Our novel sound field hearing test for CROS/BiCROS HA users, which presents appropriate noise stimuli via headphones to the better ear, appears to be a feasible approach for CROS/BiCROS HA users.
The development of the institution of serving a sentence of imprisonment on the territory of the Belarusian lands in the XVIII century
Authors: Buryj Vitalij
Published: September 2023

The article systematically examines the development of the institution of serving a sentence of imprisonment on the territory of the Belarusian lands in the XVIII century. Due to the fact that the Belarusian lands of this period were part of both the Polish-Lithuanian Commonwealth and the Russian Empire, the influence of the two legal systems of these states on the development of this institution is noted. The attention is focused on the fact that the main normative legal acts regulating the development of the institution of serving a sentence of imprisonment on the territory of the Belarusian lands at that time should be recognized as the statute of the Grand Duchy of Lithuania, Russian and Zheimot of 1588, the Cathedral Code of 1649, the Military Article of 1715 and the manifesto "Institutions for the administration of provinces" dated November 7, 1775. Expanding the influence of Russian law, including criminal law (and its constituent penal enforcement rights), on the territory of the Belarusian lands occurred according to the rule of "soft influence", enshrined in various decrees and charters of the Russian rulers. It is concluded that the institution of serving a sentence in the form of imprisonment in the Belarusian territories began to develop actively both legally and organizationally only under the influence of a more systematic Russian criminal law in the last quarter of the XVIII century, in connection with the three sections of the Polish-Lithuanian Commonwealth and the annexation of all Belarusian lands to the Russian Empire since 1795.
Politically Reflexive Foresight
Authors:   , Rutting Lucas
Published: September 2023

This dissertation focuses on the application of foresight—methods for anticipating uncertain futures—in governance of social-ecological systems (SES). SES are complex adaptive systems characterized by uncertainty and unpredictability, and to govern them effectively, future uncertainty has to be taken into account. Governing SES is inherently political, as different stakeholder groups perceive SES differently, and their stakes may differ and even conflict with each other. However, strikingly, the majority of SES scholarship—as well as foresight for SES governance—tends to pay little attention to the social and normative dimensions of SES, or to the role of power dynamics. As a consequence, there is the risk of reproducing existing—often unsustainable—power dynamics, which may reduce the space for imagining radically different, transformative futures as alternatives to explorations of futures that are still very much rooted in present-day business-as-usual thinking. All in all, one could say that the practice of foresight for SES governance does not sufficiently take into account the politics at play. I therefore argue that there is a need for more political reflexivity within foresight for SES governance.

This dissertation investigates a number of avenues for improving the political reflexivity of foresight for SES governance. It explores how adjacent critical fields of scholarship can contribute to improving foresight for SES governance and subsequently zooms in on a number of specific, promising contributions: how insights from critical systems theory can enhance participatory system and problem framing; how being reflexive towards the way in which societal imaginaries are expressed in the futures imagined in foresight processes can increase the inclusiveness and potentially inform more ambitious and transformative policies; and how bottom-up niche initiatives—disruptive seeds—that challenge the current unsustainable status quo can improve the transformative potential of foresight for SES governance.

This dissertation concludes that a politically reflexive mode of foresight can help to address a specifically problematic aspect of current environmental research agendas: they are dominated by the natural sciences and tend to focus on changes in the Earth’s biogeochemical characteristics and processes, which often has little use for informing policy action, and—worse—might even serve vested interests. It could be argued that we need to profoundly transform environmental research and to shift our attention to approaches rooted in the social sciences and humanities and to participatory research, in which politically reflexive foresight can play a crucial role. In addition, this dissertation concludes that academia in general should become more future-oriented. There is still much to gain, both in research and higher education. It is crucial to confront and address the structural and institutional challenges in terms of funding for futures research, especially in the realms of the social sciences and humanities, capacities, and training.
A Bibliometric Analysis of Systems Thinking Research in Science Education 1991–2022
Authors:   Department of Social Studies Education, Faculty of Education, Uşak University, Uşak, Türkiye, Bozkurt Erkan
Published: September 2023

This study aimed to exhibit a bibliometric analysis of systems thinking (ST) research in the field of science education. A total of 340 articles from 201 sources indexed in the Web of Science database in the years 1991–2022 were used in the analysis. The analysis aimed to provide a review of systems thinking research in science education by identifying the dynamics of research by presenting the periodical process, current situation, and future directions. Research on systems thinking has been acknowledged to demonstrate a significant increase in recent years. Bibliometric data prove that systems thinking research concerning studies in science education exhibits a parallel increase too. This is mainly due to UNESCO’s (2015) declaration of The Education for 2030 Framework for Action. There systems thinking was defined as a key competency among eight competencies for education for sustainable development. Correspondingly, the analysis in this study suggests that systems thinking research in science education is a lively and developing subject in the past decade.
Editorial
Authors:   Department of Science Education, Faculty of Education, Dokuz Eylul University, Dean, Faculty of Education, Usak University, Türkiye, Cavas Bulent
Published: September 2023

Editorial Volume 34, Issue 3, 2023
Kvalitativ (digital) kompetens: En studie av multimodalitet i svenskundervisningen på högstadiet och gymnasiet
Authors: Martín Bylund Anna
Published: September 2023

Vari består egentligen digital kompetens i relation till skolans undervisning? Kan en sådan definieras på en generell, ämnesövergripande nivå eller behöver begreppet nyanseras i interaktion med skolans olika ämnen? I den här boken adresserar vi didaktiska frågor som uppstår i relation till en pågående, global och till stora delar digitalt driven förändring av samhället och därmed skolan. Denna förändring påverkar om inte innebörden av, så i alla fall de praktiska uttrycken för en tänkande, kunskapsskapande individs mest grundläggande förmågor: att läsa och skriva; att kommunicera; att hantera olika typer av text i olika typer av sammanhang. Ett begrepp som inte sällan dyker upp när mötet mellan dessa förmågor och samhällets förändring diskuteras är just digital kompetens. Begreppet har ofta använts, exempelvis i olika policy-, strategi- och styrdokument (Utbildningsdepartementet, 2017) med ett kvantitativt fokus på att digitala verktyg ska tas i bruk i undervisningen, helst i alla lärares klassrum och helst så mycket som möjligt. Den implementering som skett av en mängd olika digitala verktyg i skolan har också fått till följd att digitala resurser ofta diskuteras i dikotomi med andra, analoga och redan befintliga resurser: den digitala (moderna) skolan ställs ofta mot (gårdagens) ”papper och penna-skola” (jfr Biesta, 2022). Detta, menar vi, är olyckligt då det skapar en falsk föreställning, som skymmer sikten för hur olika resurser – digitala såväl som analoga – kan fungera på olika sätt, erbjuda olika möjligheter i olika situationer, för olika personer och i relation till olika syften, såväl i som också utanför skolans värld.
A curricular model to train doctoral students in interdisciplinary research at the food-energy-water nexus
Authors: Murray Rianna Teresa , Marbach-Ad Gili , McKee Kelsey , Lansing Stephanie , Winner Megan Elizabeth , Sapkota Amy Rebecca
Published: September 2023

Food, energy and water (FEW) systems are inextricably linked, and thus, solutions to FEW nexus challenges, including water and food insecurity, require an interconnected science and policy approach framed in systems thinking. To drive these solutions, we developed an interdisciplinary, experiential graduate education program focused on innovations at the FEW nexus. As part of our program, PhD students complete a two-course sequence: (1) an experiential introduction to innovations at the FEW nexus and (2) a data practicum. The two courses are linked through an interdisciplinary FEW systems research project that begins during the first course and is completed at the end of the second course. Project deliverables include research manuscripts, grant proposals, policy memos, and outreach materials. Topics addressed in these projects include building electrification to reduce reliance on fossil fuels for heating, agrivoltaic farming to combat FEW vulnerabilities in the southwestern United States, assessment of food choices to influence sustainable dining practices, and understanding the complexities of FEW nexus research and training at the university level. Evaluation data were generated from our first three student cohorts (n = 33 students) using a mixed method, multi-informant evaluation approach, including the administration of an adapted version of a validated pre-post-survey to collect baseline and end-of-semester data. The survey assessed student confidence in the following example areas: communication, collaboration, and interdisciplinary research skills. Overall, students reported confidence growth in utilizing interdisciplinary research methods (e.g., synthesize the approaches and tools from multiple disciplines to evaluate and address a research problem), collaborating with range of professionals and communicating their research results to diverse audience. The growth in confidence in the surveyed areas aligned with the learning objectives for the two-course sequence, and the interdisciplinary project experience was continually improved based on student feedback. This two-course sequence represents one successful approach for educators to rethink the traditional siloed approach of training doctoral students working at the FEW nexus.
Exploring the potential of onboard energy scavenging subsystems for generating valuable data
Authors: Yaqub Raziq , Bandyopadhyay Alak , Ali Hassan
Published: September 2023

We propose implementing an onboard energy scavenging subsystem utilizing piezoelectric materials, which serves the dual purpose of generating electrical energy and facilitating data acquisition for multifaceted applications. In a practical demonstration, we have engineered a fully functional prototype adept at gathering data via a piezoelectric-centric energy scavenging mechanism. This gathered data is seamlessly synchronized with GPS coordinates and timestamps, meticulously organized within a system architecture, and harnessed through meticulously crafted Python code. The wealth of data that we obtain from an onboard energy scavenging subsystem holds significant potential. It empowers us to discern road irregularities and potholes through intricate analytical methodologies while also facilitating a thorough assessment of asphalt quality. Furthermore, it enables real-time surveillance of vehicular suspension system health and offers a nuanced exploration of driver behavior patterns. In a pragmatic pursuit of actionable insights, the amassed data can be expeditiously conveyed to relevant authorities. These authorities can perform even deeper Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL) to proactively initiate timely corrective measures, thereby elevating road safety standards and ensuring the maintenance of critical infrastructure. The Results and Discussion section underscores the attainment of substantial and noteworthy outcomes, further affirming the significance of our findings.
Curation and expansion of the Human Phenotype Ontology for systemic autoinflammatory diseases improves phenotype-driven disease-matching
Authors: Maassen Willem , Legger Geertje , Kul Cinar Ovgu , van Daele Paul , Gattorno Marco , Bader-Meunier Brigitte , Wouters Carine , Briggs Tracy , Johansson Lennart , van der Velde Joeri , Swertz Morris , Omoyinmi Ebun , Hoppenreijs Esther , Belot Alexandre , Eleftheriou Despina , Caorsi Roberta , Aeschlimann Florence , Boursier Guilaine , Brogan Paul , Haimel Matthias , van Gijn Marielle
Published: September 2023

Introduction

Accurate and standardized phenotypic descriptions are essential in diagnosing rare diseases and discovering new diseases, and the Human Phenotype Ontology (HPO) system was developed to provide a rich collection of hierarchical phenotypic descriptions. However, although the HPO terms for inborn errors of immunity have been improved and curated, it has not been investigated whether this curation improves the diagnosis of systemic autoinflammatory disease (SAID) patients. Here, we aimed to study if improved HPO annotation for SAIDs enhanced SAID identification and to demonstrate the potential of phenotype-driven genome diagnostics using curated HPO terms for SAIDs.

Methods

We collected HPO terms from 98 genetically confirmed SAID patients across eight different European SAID expertise centers and used the LIRICAL (Likelihood Ratio Interpretation of Clinical Abnormalities) computational algorithm to estimate the effect of HPO curation on the prioritization of the correct SAID for each patient.

Results

Our results show that the percentage of correct diagnoses increased from 66% to 86% and that the number of diagnoses with the highest ranking increased from 38 to 45. In a further pilot study, curation also improved HPO-based whole-exome sequencing (WES) analysis, diagnosing 10/12 patients before and 12/12 after curation. In addition, the average number of candidate diseases that needed to be interpreted decreased from 35 to 2.

Discussion

This study demonstrates that curation of HPO terms can increase identification of the correct diagnosis, emphasizing the high potential of HPO-based genome diagnostics for SAIDs.
From the West to the East: an evidence-based educational reform for modern medical students in traditional Chinese medicine learning
Authors: Liu Zhenrui , Ren Zhixuan , Fang Linhan , Liao Yuxuan , Ren Dan , Yu Yao , Qin Yixuan , Wu Jianzhen , Rong Pengfei
Published: September 2023

Introduction

Generally, Traditional Chinese Medicine (TCM) courses are now given to modern medicine students without proper course scheduling, resulting in poor teaching results.

Methods

To analyze the main factors affecting TCM learning, we surveyed the medical students and TCM teachers from Xiangya School of Medicine of Central South University via online questionnaires. The questionnaire comprised two parts, the students' part included the basic information, the subjective cognition in TCM, the attitude toward TCM course arrangements, and the attitude toward curriculum content and the design of TCM. The teachers' part included the basic information, the attitudes and opinions on TCM course arrangements, and suggestions and views on TCM teaching reform. The related data were collected from 187 medical students divided into two groups, namely, clinical medical students and non-clinical medical students.

Results

We found a more positive attitude toward TCM [including “Scientific nature of TCM” (P = 0.03) and “Necessity for modern medicine students to learn TCM” (P = 0.037)] in clinical medical students compared with non-clinical medical students, clinical and non-clinical medical students tended to find TCM courses difficult, and the students prefer clinical training to be better than theoretical teaching, while the teachers believe that lecture-based education should have a more significant proportion.

Discussion

Hence, to optimize the current TCM teaching, we conducted education reform, including differentiated teaching, hybrid teaching, and selective teaching.
Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex
Authors: Santini Lorenzo , Duranti Claudia , Palandri Chiara , Giammarino Lucrezia , Musumeci Monica , Carlucci Lucia , Capitani Chiara , Colasurdo Rossella , Recchia Fabio , Cerbai Elisabetta , Coppini Raffaele , Arcangeli Annarosa
Published: September 2023

Introduction: In the last decades, mounting evidence has pointed out the human ether-á-go-go–related gene (hERG1) potassium channel as a novel biomarker in human cancers. However, hERG1 sustains the cardiac repolarizing current IKr and its blockade can induce a prolonged QT interval at the ECG, which increases the risk of life-threatening arrhythmias. This represents a major hindrance for targeting hERG1 for antineoplastic therapeutic purposes. Based on our discovery that hERG1 resides in a macromolecular complex with the β1 subunit of integrin adhesion receptors only in tumors, and not in the heart, we generated (and patented WO2019/015936) a novel engineered, single chain, bispecific antibody in the format of a diabody (scDb-hERG1-β1). This antibody has been proven to target with high affinity the hERG1/β1 integrin complex and to exert a good antineoplastic activity in preclinical mouse models.

Methods: In the present study, we evaluated the cardiac safety of the scDb-hERG1-β1, determining the action potential duration (APD) of human cardiomyocytes, either atrial (from valve-disease patients) or ventricular (from aortic stenosis patients). Cardiac cells were incubated in vitro with i) the scDb-hERG1-β1, ii) the full length anti-hERG1 monoclonal antibody (mAb-hERG1) and iii) its single chain Fragment variable derivative (scFv-hERG1), from which the scDb-hERG1-β1 was assembled. All the tests were performed before and after treatment with the specific hERG1 blocker E4031. In addition, we have performed preliminary experiments, analyzing the effects of the scDb-hERG1/β1 in vivo measuring the QT interval length of the surface ECG after its injection intravenously in farm-pigs.

Results: The scDb-hERG1-β1 did not produce any lengthening of APD compared to control (vehicle) conditions, either in atrial or ventricular cardiomyocytes, whereas both the hERG1-mAb and the scFv-hERG1 produced a significant APD prolongation. The addition of E4031 further prolonged APD. The scDb-hERG1-β1 did not produce any alterations of the QT (and QTc) interval values, once injected intravenously in farm pigs.

Discussion: Overall, the above evidences plead for the cardiac safety of the scDb-hERG1-β1, suggesting that an application of this antibody for anti-cancer therapy will be untainted by cardiotoxicity.
Memorization strategy and foreign language learning: a narrative literature review
Authors: Wang Qunfeng
Published: September 2023

Memorization strategy as a subset of language learning strategy (LLS) has long been investigated to explain foreign language learners’ learning behaviors and uncover the role that it plays in foreign language learning (FLL). In the past half century, the focus of memorization research in FLL has been shifted from Memorization, Vocabulary Memorization to Text Memorization, which are termed with consideration of the length of language material to memorize. Since memorization strategy use is greatly influenced by varieties of psychological and socio-culture variables, the memorization strategy system becomes more complicated in the process of FLL. The present narrative review attempts to provide an overview of memorization strategy research in the field of FLL by discussing the concepts, categorizations, uses, instructions and influential factors of the three types of memorization strategies. By reviewing the existing studies, this paper proposes that in future research, diversified methods be deployed with the expansion of research perspectives and the enrichment of research topics to reveal the relationship between memorization strategy and FLL more extensively.