bluuebunny/crossref_metadata_2025 huggingface dataset:
Second opinions and pathological review impact the clinical management of patients with muscle-invasive bladder cancer
Authors: Kawahara Takashi , Nitta Satoshi , Shiga Masanobu , Nagumo Yoshiyuki , Kandori Shuya , Negoro Hiromitsu , Sakamoto Noriaki , Matsubara Daisuke , Nishiyama Hiroyuki
Published: September 2024

Purpose
Studies evaluating inter-institutional discrepancies in muscle-invasive bladder cancer diagnosis, particularly when radical cystectomy is recommended, are scarce. In this study, we aimed to examine the inter-institutional concordance rate of pathological stages in patients diagnosed with muscle-invasive bladder cancer.
Methods
We reviewed tissue samples from patients pathologically diagnosed with muscle-invasive bladder cancer at other hospitals who subsequently sought a second opinion at our hospital between January 1, 2013 and December 31, 2023. Data were acquired retrospectively by retrieving clinical data from medical records. We investigated the inter-institutional concordance rate of pathological stages assigned to each patient and examined the tumor characteristics and prognoses of patients with pathological stage discrepancies.
Results
Of the 170 patients evaluated, 22 (12.9%) were downstaged upon pathological examination at our hospital. The tumor characteristics of stage discrepancy cases were small tumor size, solitary lesions, and vesical imaging reporting data system score < 3. Eleven patients were treated for non-muscle-invasive bladder cancer based on the re-evaluation findings. Eight patients had no evidence of disease, two patients had Ta bladder recurrence, and one patient had lung metastasis despite no bladder recurrence.
Conclusion
This study highlights the importance of pathological re-evaluation of patients diagnosed with muscle-invasive bladder cancer. The significant discrepancy rate and its impact on the treatment decisions are noteworthy. Standardization of diagnostic practices is essential to mitigate variability among pathologists and facilities and to ensure optimal care for patients with muscle-invasive bladder cancer.
Physical Restraint and Ethical Sensitivity in Intensive Care: From the Physician and Nurse Perspective
Authors: GUNES Tunay , AVCI NİLGUN
Published: September 2024

Introduction: The study examined the knowledge, attitudes, and practices of nurses and physicians in the intensive care unit regarding physical restraint and ethical dilemmas.
Methods: The study was conducted in four hospitals in Istanbul between February and July 2018 in a descriptive, cross-sectional, and correlational design. The sample consisted of 113 physicians and nurses. The data was collected using a personal information form, a moral sensitivity questionnaire, a nurses' knowledge level, attitudes, and practices scale regarding physical restraints, a Richmond sedation and agitation scale, and a motor activity assessment scale.
Results: 89.4% of the nurses and 78.9% of the physicians had used physical restraint before, 98.9% of the nurses and all of the physicians said that physical restraint could be applied when necessary. It was found that the mean practice score of nurses regarding the use of physical restraints (37.01±3.45) was higher than the practice score of physicians (33.57±5.38), while their knowledge and attitude scores were lower. It was determined that nurses had lower moral sensitivity than physicians due to their higher scores on the moral sensitivity questionnaire. It was found that the gender of healthcare workers and the previous use of physical restraint did not affect moral sensitivity. In contrast, the level of education and the status of working in a private hospital negatively affected moral sensitivity.
Dıscussıon: Conclusion: It was observed that the rate of physical restraint application was high in healthcare workers; moral sensitivity was affected by occupation, educational status, institution of employment, knowledge, attitudes and practices related to physical restraint.
Genomic Characterization and Probiotic Properties of Lactiplantibacillus pentosus Isolated from Fermented Rice
Authors: Cheruvari Athira , Kammara Rajagopal
Published: September 2024

This study focused on a potential probiotic strain of Lactiplantibacillus pentosus (strain krglsrbmofpi2) isolated from traditional fermented rice in India. The study aimed to conduct preliminary genetic and phenotypic characterization. The strain has a genome size of 3.7 Mb, a GC content of 46%, and 3192 protein-coding sequences, as determined by genomic analysis. Subsequently, various bacteriocins, the CRISPR Cas system, phage genes, plasmids, pathogenicity, and antibiotic resistance were identified using bioinformatic methodologies. Biochemical and biophysical examinations improved our understanding of hydrophobicity, antioxidant activity, antibiotic resistance, auto-aggregation, co-aggregation properties, and tolerance to the simulated gastrointestinal condition. The safety assessment of the isolated L. pentosus was evaluated based on the hemolytic activity. The strain has demonstrated strong antibiotic activity against pathogens considered WHO priorities, such as Salmonella enterica subsp. enterica ser. Typhi, Clostridium perfringens, Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, and Vibrio cholerae. Our findings suggest that gaining a deep understanding of the genetic and functional characteristics of the L. pentosus strain could pave the way for its application as a beneficial probiotic in the food industry.
Beyond the Degree: Fertility Outcomes of `First in Family' Graduates
Authors: Adamecz Anna , Lovász Anna , Vujić Sunčica
Published: September 2024

This paper looks at the relationship between higher education and fertility, focusing on how inter-generational educational mobility shapes this dynamic. Using the 1970 British Cohort Study, we estimate gaps in completed fertility, distinguishing between those who are the first in their family to graduate from a university (FiF), graduates with a graduate parent, and non-graduates. Our findings reveal that while on average, graduate women have fewer children than non-graduates, this difference is driven by FiF graduates. FiF women tend to have fewer children than both non-FiF graduates and non-graduates, who exhibit similar fertility rates. The fertility gap between FiF and non-FiF graduates emerges after age 35, mainly on the extensive margin: FiF women are more likely to remain childless, but those who become mothers have an equal average number of children. Similar patterns are observed among men, although the gaps are smaller and not statistically significant. We identify child-related preferences, self-esteem, and maternal employment in childhood as potential explanations behind the FiF fertility gap, while labour market outcomes, financial constraints, partnerships, and health do not appear to play a role. These findings underscore important considerations for supporting inter-generational mobility and fertility.
JEL codes: I26, J13, J16, J24
Research on the Initial Configuration Scheme of China’s Carbon Market Based on Carbon Emission Reduction Target Constraints
Authors: Wu Zhenni , Li Sijing , Sun Huaping , Yin Yingkai
Published: September 2024

Under the “Double Carbon” goal, incorporating the principles of equity, efficiency, and responsibility into the initial regional allocation of carbon emission rights is the key to promoting and optimizing China’s carbon trading market. This paper first defines the net carbon transfer responsibility between regions, then calculates the regional carbon allowance scheme based on the principles of equity and efficiency, as well as integrating principal. Our study shows that: (1) the provinces which transfer out carbon emissions are dominated by Jiangsu, Zhejiang, Shanghai and carbon trading pilot regions, while the provinces which transfer in are dominated by Shanxi, Hebei and Inner Mongolia. (2) Considering only the principle of equity will reduce the incentive for carbon emission reduction in regions with high emission reduction efficiency, such as Beijing, Shanghai and Guangdong; while considering only the principle of efficiency will exacerbate the pressure to reduce emissions in Xinjiang, Shanxi, Inner Mongolia and other high carbon emission regions. (3) Compared with equity and efficiency principle, integrated principle not only takes into account multiple factors, but also reduces the cost of carbon emission reduction among regions, which is more in line with China’s “dual-carbon” strategy.
Preparation of ultra-low ash coal from non-stick coal by using high-speed shear-selective agglomeration flotation
Authors: Deng Xiaowei , Wu Jinwen , Guo Wenzhen , Chen Le , Zhong Guolong
Published: September 2024

Coal contains a large amount of ash, resulting in coal combustion of nitrogen oxides, sulfur dioxide and other heavy metal particles have a serious impact on the ecological environment. The preparation of ultra-low ash coal has become a major means to improve the utilization rate of coal resources. Therefore, this study takes a non-stick coal as the research object. The optimum flotation process and pharmaceutical regime were explored by high-speed shear hydrophobic agglomerate flotation. The results demonstrate that non-stick coal by high-speed shear hydrophobic agglomerate flotation can reduce the ash content of the original coal by 10.5–1.49%, with a yield of up to 54.93%. In addition, the experiment also found that high-speed stirring can overcome the energy barrier of particle interaction, making the hydrophobic particles more dense, which is more conducive to effectively separating clean coal and inorganic minerals. This study provides an effective way for high value-added utilization of coal, and provides reference for realizing the fine and clean utilization of coal resources.
The effects of diatom polyunsaturated aldehydes on embryonic and larval zebrafish (Danio rerio)
Authors: Raymer Rachel , Jessa Soraya M. , Cooper W. James , Olson M. Brady
Published: September 2024

Marine diatoms are pervasive in many planktonic and benthic environments and represent an important food source for a wide range of species. Some diatoms produce polyunsaturated aldehydes (PUAs) as defensive toxins. PUA exposure is known to reduce the fecundity of invertebrate grazers like copepods and echinoderm larvae, but little is known about the effects of PUAs on vertebrates. Many fish species are likely to come into close contact with diatoms. Many may deposit eggs on diatom-coated substrates, consume diatoms as larvae, and/or feed heavily on zooplankters that may be gut-loaded with diatoms. The purpose of this study was to test whether dissolved diatom PUAs affect the early life stages of a model fish, Danio rerio (zebrafish). To test this, zebrafish embryos and larvae were exposed to proportionally increasing mixtures of the dissolved diatom PUAs 2E,4E-decadienal, 2E,4E-octadienal and 2E,4E-heptadienal. Under PUA exposure, three metrics of fitness were assessed: embryo heart rate, larval size at hatch, and pre-feeding mortality rate. Zebrafish embryos exposed at 24 hours post fertilization (hpf) experienced decreased average heart rate after 2 days of PUA exposure. Embryos 24 hpf exposed to PUA mixtures for 6 days showed a reduction in size in comparison to embryos from controls. Embryos exposed to PUAs from 2 hpf until death showed lower survivorship compared to larvae in controls. The results of this study suggest that larval fish that are sympatric with PUA producing diatoms during their embryonic and larval stages may be susceptible to detrimental effects from PUA exposure.
Adaptive Rate Compression for Distributed Video Sensing in Wireless Visual Sensor Networks
Authors: Song Zhen , Chen Jianhua
Published: September 2024

Distributed compressive video sensing (DCVS) for wireless visual sensor networks faces challenges due to computational limitations and bandwidth constraints. This paper presents a rate-adaptive DCVS scheme that dynamically allocates measurements based on temporal correlation and sparsity estimation. By skipping highly correlated blocks and adaptively sampling others, the proposed method achieves improved rate-distortion performance with reduced sampling complexity and transmission burden. Experimental results demonstrate substantial gains over state-of-the-art methods, especially for videos with varying motion speeds. Codes and data are available at https://github.com/SongHere/USE_DCVS.
Kompetent oder zu erziehend?
Authors: Sieber Egger Anja , Unterweger Gisela
Published: September 2024

Dass Eltern für die Schule wichtig sind, wissen die Mitarbeitenden der Bildungsinstitutionen schon lange. Die erste Begegnung zwischen Eltern und Schule ist der Eintritt in den Kindergarten, oft im Rahmen eines Elternabends. Wie werden Eltern angesprochen und adressiert, welche Annahmen über Eltern verraten die Elternabende, wenn genauer hingeschaut wird?
A IMANÊNCIA RADICAL
Authors: Bordron Jean François
Published: September 2024

Este artigo propõe uma leitura do princípio da imanência formulado por Hjelmslev. Ele interpreta este princípio não como uma vontade de limitar a pesquisa a um único domínio de objeto, a língua, por exemplo, mas como um convite à construção de interfaces entre domínios que à primeira vista parecem disjuntos. Assim, pode-se esperar construir o que Hjelmslev chama de “imanentismo de ordem superior”. Essa compreensão do princípio da imanência se estende a todos os domínios das ciências humanas (antropologia, psicologia etc.), entre os quais é sempre difícil encontrar um ponto de vista comum. De forma mais geral, ele convida a encontrar um certo número de afinidades e lugares de coerência entre os elementos de uma multiplicidade, como, por exemplo, os diferentes regimes temporais unidos no mesmo momento presente. Esta interpretação do princípio da imanência se entende como uma ferramenta epistemológica no contexto de uma semiótica das culturas.
A ENUNCIAÇÃO (UMA POSTURA EPISTEMOLÓGICA)
Authors: J. Greimas Algirdas
Published: September 2024

Não há resumo
DESINFORMAÇÃO E EPIDEMIA SEMIÓTICA: COMENTÁRIOS A PARTIR DO FILME PONTYPOOL
Authors: Ripoll Leonardo , Romanini Vinicius
Published: September 2024

O artigo explora a proposta de significação como infecção semiótica, a partir da análise de Pontypool, filme cinematográfico canadense de 2008. A história se passa em um dia atípico de uma estação de rádio local, quando estranhos eventos de uma infecção linguística generalizada que acontece na pequena cidade rapidamente irrompem o estúdio de transmissão, demandando uma disrupção na lógica de compreensão dos signos conhecidos até então. O texto, assim, procura relacionar ideias extraídas da narrativa do filme com o contexto contemporâneo tomado pelo fenômeno da desinformação, abordando a semiótica de matriz peirceana como sustentação teórica e metodológica na elaboração das reflexões trazidas.
PANTALLAS COLECTIVAS: EXPERIENCIA MUSEAL Y DISPOSITIVOS MÓVILES
Authors: Rosso Aluminé
Published: September 2024

En este artículo se analiza las nuevas prácticas de visita surgidas a partir de la incorporación del teléfono móvil a la experiencia museal. Estas prácticas, que nacen como acuerdos con la institución, son incorporadas a los contratosprevistos por la organización del espacio físico del museo, y promovidas en el espacio virtual, sus redes sociales.
 
Se exponen, entonces, algunos de los resultados de los trabajos de campo realizados en el Museo Reina Sofía (2021-2023) en los que los comportamientos de los visitantes, concretamente, el uso de los teléfonos móviles fue estudiado bajo una perspectiva semio-etnográfica; y del análisis de los contenidos publicados por los usuarios que retoman los hashtagspropuestos por el museo o que mencionan su perfil institucional.
 
La puesta en relación de estas dos instancias de análisis ha permitido: 1- examinar los modos en los que las instituciones configuran y hacen convivir distintos tipos de públicos, a los cuales he provisoriamente he llamado, visitantes museales y followers museales; 2- observar las maneras en que estos tipos de público habitan en el espacio museal físico-virtual, y 3- analizar el tipo de huellas públicas (contenidos de Instagram) que estos públicos dejan en el espacio virtual del museo.
Um estudo inicial sobre as oportunidades de utilização do Metaverso no Ensino em Saúde
Authors: Silva Marcos Antonio , Littleton Lage Gabriel Maranduba , Fernandes Pereira Anrafel
Published: September 2024

Tradicionalmente os profissionais da saúde passam por uma formação acadêmica mais fundamentada em um tipo de ensino e aprendizagem conservador. Geralmente, esse modelo educacional faz o uso de poucos recursos tecnológicos, tais como a realidade virtual (VR). Entretanto, este cenário vem mudando. A adoção de abordagens inovadoras e a utilização de novas tecnologias como facilitadoras do processo de ensino-aprendizagem já vem sendo percebida em alguns ambientes educacionais. Uma dessas tecnologias de realidade virtual é o metaverso, que permite a interação imersiva do usuário com aplicações computacionais, possibilitando uma experiência mais realista. Diante disso, este trabalho apresenta uma investigação inicial sobre os benefícios e oportunidades que esta tecnologia traz para o ensino em saúde. Um estudo experimental preliminar foi realizado com um grupo para avaliar a experiência dos participantes neste ambiente. Os resultados obtidos corroboram o potencial da tecnologia para o ensino na área da saúde.
Cuidados de enfermagem às pessoas idosas em situação de abandono por seus próprios familiares.
Authors: Ferreira Bernardo Andréia , Ramos de Almeida Mariana , Almeida Pinto Alvaro Souza Mônica , Duarte Rodrigues Luana , Da Terra Lapa Alessandra
Published: September 2024

O envelhecimento da população é um fenômeno que vem ocorrendo em diversos países, inclusive no Brasil. Muitas pessoas idosas enfrentam diferentes formas de violência, sendo o abandono um tipo frequente. É caracterizado pela ausência de cuidado essencial à vítima, seja por parte de um membro da família ou outras pessoas que possuem vínculos. Objetivou-se analisar a importância dos cuidados de enfermagem frente à pessoa idosa abandonada por seus familiares e identificar as características sociodemográficas envolvidas.Realizada revisão integrativa nas bases de dados MEDLINE, LILACS e BDENF, buscandoartigos na íntegra, em português, no período 2018-2023, sendo selecionados 15 artigos. Observou-se variações na incidência e nos perfis das vítimas e perpetradores, ligados a fatores socioculturais. Ficou evidente a importância de ações educativas, o papel da equipe de saúde, especialmente do enfermeiro, bem como a importância da espiritualidade na recuperação dos idosos.
impacto do processo morte e morrer em profissionais de enfermagem atuantes em UTI Neonatal
Authors: Santos Eliane Silveira dos Santos , Da Silva Dantas dos Anjos Gilcéia , Celestino dos Santos Paz Nilma , Magalhães Rita de Fátima , Santana Goes da Silva Amanda , Dias de Mello Pereira Raphael
Published: September 2024

A morte neonatal é um evento complexo que pode levar o enfermeiro a enfrentar o processo de luto, ao mesmo tempo em que pesquisas que visam compreender a respeito da saúde mental de profissionais que atuam em ambiente hospitalar demonstrarem que a UTI neonatal é o setor mais relacionado ao adoecimento psíquico desses profissionais. Diante a isto, este estudo será realizado com objetivo de revisar na literatura científica nacional os impactos de assistir e cuidar na UIT neonatal à saúde mental dos profissionais de enfermagem. Para sua confecção a metodologia de revisão integrativa de literatura será aplicada no segundo semestre de 2023 nas seguintes bases de dados: Biblioteca Virtual da Saúde (BVS), a Scientific Electronic Library Online (SciELO) e a Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). A pesquisa revisou 416 artigos sobre o adoecimento psíquico de profissionais de enfermagem na UTI Neonatal. Após seleção, 7 artigos foram discutidos, demonstrando que os sentimentos dos enfermeiros mediante a morte neonatal são culpa, tristeza, impotência e frustração. Esses profissionais também enfrentam dilemas éticos na decisão sobre cuidados paliativos e comunicação de más notícias. A criação de vínculo com a família, diálogo, sinceridade e grupos de apoio emergem como alternativas para o enfrentamento dos sentimentos e dilemas frente a morte neonatal.
A contribuição do pescado na agregação de renda de comerciantes dos mercados municipais de Imperatriz, MA
Authors: Silva Thiago , Bezerra Oliveira Allison , Henrique da Silva Freitas Pedro , Olinto Branco Joaquim
Published: September 2024

A comercialização de pescado tem sido amplamente discutida no Brasil, principalmente por considerar inúmeros fatores que  afetam na qualidade dos produtos ofertados aos consumidores. Este artigo tem como objetivo analisar como implantação de mercados municipais tem surtido efeitos para a geração de renda aos comerciantes de pescado na cidade de Imperatriz/MA. A base teórica para esta pesquisa foi conduzida por meio de buscas em artigos, dissertações, teses, legislação e demais documentos científicos que aprofundam essa discussão. Verificou-se que a construção desses mercados são essenciais para a garantia de adequação dos produtos nas condições sanitárias de manutenção/acondicionamento adequados para a comercialização, sendo necessário, portanto, para o atendimento não somente a esta necessidade quanto à população que consome o pescado, sobretudo, para o fortalecimento dos agentes que envolvem a economia e toda a cadeia produtiva da pesca.
uso das tecnologias digitais de informação e comunicação - TDIC na concepção freiriana e suas contribuições para o ensino de humanidades
Authors: Leal Bernardo Luiz Fernando , Ferreira Rodrigues Rodrigo , Moreto Charles , Luzia Folador Berger Mariane
Published: September 2024

O presente trabalho busca discutir as Tecnologias Digitais de Informação e Comunicação – TIDC, à partir de um viés freiriano. Sendo assim foi realizado um estudo bibliográfico, tendo como objetivo discutir o uso das tecnologias digitais TIDC na concepção freiriana, assim como suas contribuições para o ensino de humanidades. Para responder este objetivo, realizou-se um ensaio descritivo a partir das seguintes abordagens: O ensino de humanidades num viés tecnológico; Alfabetização Digital x Educação Bancária e o Papel da Escola na Cultura Digital. Com este trabalho, foi possível refletir sobre os estudos tecnológicos numa perspectiva freiriana, demonstrando que o acesso às tecnologias não garantem a efetivação de uma educação dialógica; sendo assim as reflexões de Freire ajudam a fomentar uma educação tecnológica, contrapondo toda prática hegemônica da educação bancária.
Apropriação da Teoria das Representações Sociais nas investigações sobre Formação de Professores para o EAD: mapeando a produção de dissertações e teses defendidas em programas brasileiros de pós-graduação
Authors: Gomes de Souza Lowise , Da Silva Triani Felipe
Published: September 2024

A atenção voltada para formação docente vem ganhando maior visibilidade dede a Constituição de 1988 na qual o preparo e formação para a docência tornaram-se fundamentais para oferecer um ensino de qualidade. Como aporte teórico para essa pesquisa, utilizou-se a Teoria das Representações Sociais proposta pro Moscovici (1961) que corresponde uma forma sociológica da psicologia social que são concepções construídas em torno dos conhecimentos de senso comum por um determinado grupo social. A metodologia utilizada foi a revisão bibliográfica que buscou na base de dados do Catálogo de Teses e Dissertações da CAPES e da Biblioteca Nacional de Teses e Dissertações pesquisas que de alguma forma se identificassem com investigações a respeito da formação de professores na modalidade EaD. Como resultados do trabalho verificou-se a necessidade de aprofundamento a respeito do que é ser professor para alunos do curso de Pedagogia EaD, devido a escassez de pesquisas que articulassem os conceitos representações sociais, formação de professores e ensino a distância.
Independência legal do Banco Central e inflação: uma análise com dados em painel para a América Latina
Authors: Tomás da Fonseca Nicolay Rodolfo , De Oliveira Nicolay Ana Jordânia , Da Silva Barbosa Marlon
Published: September 2024

A Independência do Banco Central (CBI) vem sendo amplamente defendida nas últimas décadas, como forma de aliviar pressões inflacionárias sem interferências políticas. Essa independência implica que um banco central pode definir os objetivos da política monetária e aplicar os dispositivos adequados para alcançar seus propósitos. Para fazer essa verificação, o presente trabalho aplicou o índice de legal CBI, apresentado por Garriga (2016), em uma amostra de 33 países da América Latina entre 1984 a 2012. Utilizamos regressões lineares com dados em painel pelo estimador de mínimos quadrados ordinários com efeitos fixos de cross-section. Os resultados indicam que a elevação do grau de independência do banco central na América Latina está associada a níveis menores de taxas de inflação. Os resultados são robustos a aplicação de diferentes modelos e especificações.
A implementação de políticas públicas no combate e prevenção à violência doméstica contra a mulher: uma análise no município de Vassouras/RJ
Authors: Crivas Fonseca Borges Bárbara , Rezende Gabriel Silva
Published: September 2024

Prevista na Constituição da República Federativa do Brasil de 1988, a igualdade entre homens e mulheres em direitos e obrigações constitui um direito fundamental a ser garantido pelo Estado por meio da criação de mecanismos para coibir a violência e proteger cada um de seus membros. A ausência de marcos legais específicos instituídos pelo Estado brasileiro demonstra um descaso em relação aos compromissos estabelecidos nas Constituição, Convenções e Tratados ratificados, desta forma, o propósito deste estudo é analisar os marcos legais específicos instituídos pelo Estado e as políticas públicas na abordagem da violência doméstica no município de Vassouras, situada no estado do Rio de Janeiro. Para tanto, a metodologia utilizada foi a pesquisa qualitativa de cunho descritiva, no intuito de compreender a implementação e o suporte sociojurídico auferido pelas políticas públicas de enfrentamento à violência contra a mulher. Constatou-se que em 2020 o percentual de registros tipificados na Lei Maria da Penha atingiu o seu pico, chegando a 63,8% neste município, período em que foram implementadas novas políticas e ações de acolhimento, atendimento e orientação às mulheres vítimas, o que contribuiu para maior conscientização e análise crítica pelas vítimas, impulsionando-as a pedirem auxílio e registrarem ocorrência sobre as violências sofridas. Pode-se concluir que as políticas, apesar de recentes, têm sido efetivas quanto aos objetivos de atender, conscientizar e reduzir os casos de violência doméstica e familiar no município.
 
Palavras-chave: Violência Doméstica; Políticas Públicas; Vassouras/RJ.
Da História às Práticas Modernas: a Função dos Óleos Essenciais na Sustentabilidade e no Controle de Insetos
Authors: Souza da Cruz Igor Luiz , Nascimento Tatiane Aparecida , Maleck Marise , Carvalho Queiroz Margareth Maria
Published: September 2024

A utilização de óleos essenciais (OEs) remonta séculos e está enraizada na extração de fitoprodutos complexos de diversas partes das plantas. Reconhecidos por suas propriedades bioativas, esses óleos essenciais são amplamente explorados em aplicações variadas, especialmente como repelentes e inseticidas naturais, em contraste com os pesticidas sintéticos prejudiciais ao meio ambiente. Esta revisão de literatura destaca o potencial dos OEs na conservação ambiental e como alternativa sustentável aos inseticidas químicos, promovendo práticas de manejo de pragas menos prejudiciais. A utilização desses compostos naturais não só minimiza a exposição a produtos químicos sintéticos, mas também promove práticas agrícolas que conservam a biodiversidade local. Com a crescente preocupação ambiental e pragas resistentes, os óleos essenciais extraídos de plantas oferecem um controle de pragas eficaz e sustentável, reduzindo a dependência de químicos e incentivando práticas agrícolas responsáveis.
Development of a Suitable Method for the Synthesis of New Thiadiazoles Using Hydrazonoyl Halides
Authors: Alarbash Munirah F. , Al-Faiyz Yasair S. , Wiggins Jeffery S. , Sayed Abdelwahed R.
Published: September 2024

Background:

Hydrazonoyl halides and methylhydrazinecarbodithioate have been generally utilized in the synthesis of heterocycles.

Methods:

This study describes a new and simple method to prepare new thiadiazoles from the reaction of N-(naphthalen-1-yl)-2-oxopropanehydrazonoyl chloride or ethyl 2-chloro-2-(2-(naphthalen-1-yl)hydrazono)acetate with methylhydrazinecarbodithioate in the presence of basic medium under reflux. In this study, the synthetic schemes are designed to show the chemical reactions. Elements analysis, Fourier Transform Infrared Spectroscopy (FT-IR), Mass Spectrom-etry (MS), and Nuclear Magnetic Resonance (NMR) are used to identify and characterize the final compounds.

Results:

There are two ways to synthesize the final thiadiazoles molecules. The first can be through nucleophile substitution of thiolate of methylhydrazonecarbodithioate to the chlorinated carbon of hydrazonoyl. Hydrochloric acid is then removed to provide an S-alkylated intermediate. Methanethiol is eliminated from this intermediate by an in situ intra-molecular cyclocondensation process to give the final products. The subsequent [3+2] cy-cloaddition involving 1,3-dipolar cycloadditions of nitrilimines to C=S is succeeded by the re-moval of methanethiol.

Conclusion:

This approach utilizes affordable, readily accessible reagents and simple reaction conditions to produce new thiadiazole derivatives with satisfactory yields.
Gut Microbiome Changes among Undernutrition and Stunting Infants and Children under 2 Years: A Scoping Review
Authors: Sundjaya Tonny , Djuwita Ratna , Adisasmita Asri C. , Tanjung Conny , Massi Nasrum , Fikri Bahrul , Pradnyaparamitha Dyah Ayu , Basrowi Ray Wagiu
Published: September 2024

Background

Undernutrition and stunting are significant public health concerns globally, particularly in low- and middle-income countries. Nutritional intervention is the cornerstone of the management and prevention of these conditions. However, the gut microbiome has recently emerged as an essential modulator of the effects of nutritional interventions in undernutrition and stunting. This scoping review aims to examine the impact of nutrition intake (including if there is any intervention) over time on gut microbiome changes in infants and children under the age of 2 who experience undernutrition and stunting.

Methods

A literature search was conducted in PubMed and Cochrane Library, including studies from 2013 to 2023, using terms related to malnutrition, stunting, failure to thrive, and gut microbiome. Inclusion criteria were applied to select eligible studies for review. Five studies were chosen to be included in this review.

Results

The findings indicate that nutrition intake over time, including dietary supplementation and prebiotics, can influence the gut microbiome composition, diversity, and functionality in undernutrition and stunting infants and children. These may promote the growth of beneficial bacteria while reducing the abundance of harmful pathogens. Moreover, improvements in nutritional status, growth parameters, and immune function were observed in association with positive changes in the gut microbiota.

Conclusion

Nutrition intake can positively modulate the gut microbiome in undernutrition and stunting infants by supporting the growth of beneficial gut bacteria such as Actinobacteria, Bacteroides, Streptococcus, Bifidobacterium, Prevotella sp, and other bacterial taxa that vary with age, ultimately contributing to enhanced growth and development outcomes. Further studies are needed to better understand the mechanisms underlying these effects and to develop targeted nutritional interventions that optimize the gut microbiome in undernutrition and stunting infants and children under 2 years.
Papaya Seed Extract Combined Lauryl Glucoside Against Human Parasites Contaminated in Fresh Vegetables
Authors: Boonsuya Alisa , Pechdee Phornphitcha , Arunsan Patpicha , Thanchonnang Chutharat , Phinsiri Sirichai , Rattanapitoon Nathkapach K. , Rattanapitoon Schawanya K.
Published: September 2024

Background:

The prevalence of parasites in Thailand, primarily transmitted through contaminated
vegetables, poses a significant public health concern. Ensuring the safety of natural produce
from both parasites and chemical residues necessitates robust sanitation measures.

Objective:

This study aims to develop effective vegetable-washing solutions using papaya seed extract
with potent anti-parasitic properties contamination in fresh vegetables.

Methods:

Fresh vegetables contaminated with Strongyloides stercoralis larvae, Ascaris lumbricoides,
and Taenia spp. eggs were subjected to various treatments: distilled water, tap water, vinegar
(5%), papaya seeds extract (200 mg/L), lauryl glucoside (1%) from coconut oil, papaya seeds extract
combined with lauryl glucoside, and Albendazole as a standard drug. Immersion for 5 minutes was
followed by parasite observation using the sedimentation method over 60 minutes, examining inhibitory
effects on parasite larvae movement.

Results:

Papaya seed extract achieved the most rapid cessation within 10 minutes for larvae movement,
followed by vinegar and papaya seed extract combined with lauryl glucoside. Furthermore,
papaya seed extract combined with lauryl glucoside exhibited the highest efficacy in the sedimentation
larval and parasite eggs, followed by lauryl glucoside solution and papaya seed extract, surpassing
the control group.

Conclusion:

Papaya seeds extract immobilized larvae, while lauryl glucoside effectively eliminated
parasite eggs from vegetables. Natural and organic compounds derived from papaya and coconut oil
exhibit inherent diversification in their properties. These compounds originate from natural sources,
showcasing distinct characteristics attributed to their organic nature. These results indicate the potential
for developing natural extract-based products as future vegetable-washing solutions, emphasizing
their significance against parasitic efficacy.
In vitro and In silico Assessment of the Antiviral Potential of Green Tea, Green Coffee, Pomegranate Peel, and Orange Peel
Authors: Sabry Noha , S.M El-Sabbagh , Mohamed Aly F. , Salama Hanaa M , Yosri Mohammed , Amin Basma H.
Published: September 2024

Background:

Viral infections pose a great burden for humankind and many
viruses have no effective treatments. Hepatitis A Virus (HAV) and Coxsackie-B4 (Cox-
B4) are common viruses having many drawbacks. Using plant extracts as antiviral agents
is a globally applied approach due to its efficacy and minimal adverse effects.

Objective:

This study aimed to test the antiviral action of the green coffee extract against
HAV and Cox-B4 viruses, assess the possible mechanisms regulating this role, and apply
molecular docking to evaluate the connection between bioactive compounds in the green
coffee extract and viral proteins and receptors.

Methods:

The antiviral effect of four plant extracts, including green tea, green coffee,
pomegranate peel, and orange peel on HAV and Cox-B4 viruses has been screened in
this study. The most promising results have been obtained using an inverted microscope
and electron microscopy. Gas Chromatography-Mass Spectrometry (GC-MS) has been
used to detect various compounds in the green coffee extract. Gene expression of MxA
has been examined in different groups of treatments. Oxidative enzymes, including Glutathione
(GSH), Superoxide Dismutase (SOD), and Malondialdehyde (MDA) were tested
in infected Vero cells (African green monkey kidney cells) and upon using green coffee.
In silico studies were performed using molecular docking software.

Results:

Green coffee has been found to have an antiviral impact on HAV and Cox-B4
with IC50= 8.8±0.6 and 14.5±0.8 μg/ml, respectively, visualizing and confirming the results
using both Transmission Electron Microscope (TEM) and inverted microscope. The
green coffee extract has been found to regulate oxidative enzymes, including SOD, GSH,
and MDA, to normal concentrations as well as MxA gene expression to regular levels.
Linoleic acid and arachidic acid have been found to be the most common molecules in
green coffee extract, interacting with the tested viruses.

Conclusion:

Green coffee methanolic extract has been found to have an efficient antiviral
impact on HAV and Cox-B4 viruses, as validated by in vivo investigations.
PENGARUH PDRB SEKTOR INDUSTRI, TRANSPORTASI, DAN PERTANIAN TERHADAP EMISI CO2 DI PROVINSI JAWA TENGAH
Authors: Hela Syafina , Ekawaty Marlina
Published: September 2024

This study aims to determine the effect of GRDP in the industrial, transportation, and agricultural sectors on carbon dioxide (CO2) emissions in Central Java Province. This study is important because there has been a change in the structure of the economy from agriculture to industry and services in Central Java, which has sparked fears of an increase in CO2 emissions that damage the quality of the environment. The objectives of this study were achieved by using time series data from 2001-2020 and analyzed by multiple linear regression. The results of this study indicate that the GRDP of the industrial sector has a positive and significant effect on CO2 emissions, the GRDP of the transportation sector has a negative and significant effect, while the GRDP of the agricultural sector has no effect.
ANALISIS PENGARUH PENGGUNAAN E-WALLET TERHADAP PERILAKU KONSUMEN (STUDI SEBAGIAN MASYARAKAT JAWA TIMUR)
Authors: Nikmah Yuliani khoirun , Dias Satria
Published: September 2024

Technological developments are changing society's paradigm from conventional traditions to the digital era, making it possible to fulfill daily needs via smartphone devices. E-Wallet, as a form of digital wallet, is an important phenomenon that is influenced by companies in improving the quality of their applications. Payments with electronic money bring efficiency and a modern lifestyle, the impact of which can be seen in more impulsive consumer behavior. This research aims to explore the deeper impact of using E-Wallets on consumer behavior in the context of ease of transactions, and the extent to which this convenience can change shopping patterns into consumer behavior among the people of East Java who use E-wallets. The research method used is a quantitative approach with surveys (distributing questionnaires), and using the Partial Least Square (PLS) method. The results of this research imply that the ease of use of E-Wallet not only provides transaction efficiency but also economic potential for consumers in East Java. Price and habit factors influence consumer behavior more than E-Wallet performance expectations. Therefore, these findings provide valuable guidance for E-Wallet service providers to design appropriate and effective strategies in the East Java market.
PERAN MASYARAKAT DALAM PENGELOLAAN SAMPAH RUMAH TANGGA
Authors: Putra Abrianto Andika Bimantara , Indraswari Citra Rahayu
Published: September 2024

Waste is the most common thing discussed in every community, especially how to manage it. With the large population of the world community, more and more waste is generated around the environment which will cause pollution. The problem that can be taken is how the community manages household waste. The method used is a descriptive qualitative method, which is the main focus in the community that manages household waste and how to overcome it in the future.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENERIMAAN PAJAK HOTEL DI KABUPATEN/KOTA PROVINSI JAWA TIMUR
Authors: Pracelia Yonanda Annisa , Fazaalloh Al Muizzuddin
Published: September 2024

The regencies/cities in the East Java Province are among the regions that possess diverse and significant potential for tourism and local resources or wealth. This research aims to determine the influence of the number of hotels, the number of tourists, the number of hotel rooms, and economic growth on hotel tax revenue in the regencies/cities of East Java Province. In this study, the chosen method is quantitative method with panel data regression analysis. The research results indicate that the Number of Hotels, Number of Hotel Rooms, and Economic Growth have a positive and significant impact on hotel tax revenue in the Districts/Cities of the East Java Province. Meanwhile, the Number of Tourists does not have a effect on hotel tax revenue in the Districts/Cities of the East Java Province.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KETIMPANGAN PENDAPATAN DI JAWA TIMUR
Authors: Raihan Daffa Naufal  , Santoso Dwi Budi
Published: September 2024

The welfare of the community is the primary goal in the economic development of a region, and this can be achieved through rapid economic growth and equitable income distribution. In reality, East Java Province has not yet achieved equal prosperity, as evidenced by an increasing trend of inequality that has not reached its lowest point during the period of this research. Therefore, there is a need to accelerate the reduction of inequality by understanding the various factors influencing inequality in East Java. Through a simultaneous model using the three-stage least square (3SLS) method, this study attempts to estimate the impact of Gross Regional Domestic Product (PDRB) per capita and the health index on income inequality. It also analyzes the factors influencing the growth of PDRB per capita in East Java. The data used for this research is sourced from the Badan Pusat Statistik (BPS) for the years 2011-2021.The research findings indicate that the growth of PDRB per capita and the health index significantly and positively affect income inequality. The factors influencing the growth of PDRB per capita in East Java include the education index and capital accumulation. Based on these results, the government and relevant stakeholders need to promote a more even distribution across sectors in each region of East Java Province and strengthen health aspects for groups with low incomes.
DETERMINAN MIGRASI INTERNASIONAL TENAGA KERJA
Authors: Salsabilla Adinda Thalia , Pratomo Devanto Shasta
Published: September 2024

Labor migration is a phenomenon that occurs in various regions, especially East Java Province as one of the provinces that has a high level of productivity. The movement of labor can be influenced by various factors. This study aims to analyze the determinants of international labor migration in East Java in 2015-2019. the type of data used in this study is secondary data. The research method used in this research is panel data regression. The results of the study show that the GRDP variable influences positively but not significantly, while poverty and unemployment   variables influences negatively and react not significantly. Meanwhile, the district/city minimum wage variable influences negatively and significantly on the number of international labor migration in East Java.
ANALISIS FAKTOR KEPUTUSAN PEREMPUAN DI KOTA MALANG UNTUK BEKERJA DI SEKTOR JASA
Authors: Zelinka Natalia Angelina  , Aminnullah Achmad Muttaqin
Published: September 2024

The female labor force participation rate has been increasing in recent years, and in the city of Malang, women tend to choose to work in the service sector. This research aims to examine the factors that drive the decision of women in Malang to work in the service sector. The method used is Factor Analysis with the goal of reducing and identifying the main factors or dominant factors that influence the decision of women in Malang to work in the service sector. The research findings indicate two main factors: Family Responsibility and Socio-Economic. Another finding in this study is the tendency of female workers to work in the informal sector, and the growth of the service sector can be seen from the many new professions that have become choices for female workers.
Development of Nutrient Control System in Plant Factory based on Growth Phases of Romaine Lettuce (Lactuca sativa var. longifolia)
Authors:   Universitas Andalas, Rozaaq Naufal Ilhamdi , Putri Renny Eka ,   Universitas Andalas, Yanti Delvi ,   Universitas Andalas
Published: September 2024

Nutrient is one of the conditions controlled in a plant factory. Nutrient control must be based on the plant growth phase, but previous research has shown shortcomings in this area. This study aims to develop a nutrient control system in a plant factory based on the plant growth phase, specifically using Romaine lettuce. The research method used is the experimental method, with research stages including system design (controller modification, programming, and TDS sensor calibration testing) and system performance testing. The TDS sensor calibration test results showed an R² of 0.9999, indicating that the TDS sensor readings are very close to those of the TDS meter. The system performance test results showed that the developed system works well in controlling nutrient levels based on the growth phase of Romaine lettuce. The planting process lasted 30 days, from October 13, 2023, to November 11, 2023, with a total of 2,697 data points recorded by Antares. Nutrient requirements were adjusted per the growth phase of Romaine lettuce, with set points in the first to fourth weeks being 500 PPM, 600 PPM, 700 PPM, and 800 PPM, respectively. The average nutrient levels recorded in the first week were 518 PPM, 623 PPM in the second week, 721 PPM in the third week, and 820 PPM in the fourth week. The TDS sensor accuracy test results showed an R² of 0.9998, indicating that the TDS sensor performed well in controlling nutrient levels during the system testing, with an average TDS sensor reading error of only 1.17%. During the planting process, the total amount of nutrients added for each of nutrients A and B was 210.10 ml, with the total operating time of the control components being 314.34 seconds for each peristaltic pump of nutrients A and B.
Karakteristik Fisiko-Kimia dan Organoleptik Sosis Analog Tepung Kacang Hijau (Vigna Radiata) dan Tepung Sukun (Artocarpus Altilis)
Authors:   Universitas Ahmad Dahlan, Kumalasari Ika Dyah , Widiyanti Atma ,   Universitas Ahmad Dahlan
Published: September 2024

Tepung kacang hijau dan tepung sukun berpotensi dijadikan bahan baku pembuatan sosis analog karena memiliki kandungan protein, serat, dan karbohidrat yang tinggi. Tujuan penelitian ini adalah untuk mengetahui karakteristik fisiko-kimia dan organoleptik sosis analog berbahan baku tepung kacang hijau dan tepung sukun. Penelitian ini menggunakan pendekatan Rancangan Acak Lengkap (RAL), komponen yang diteliti adalah perbandingan tepung kacang hijau dan tepung sukun (100, 75, 50, 25, dan 0%). Parameter yang diamati meliputi uji kadar air, protein, serat kasar, abu, lemak, karbohidrat, OHC (Oil Holding Capacity), WHC (Water Holding Capacity) dan organoleptik. Analisis yang digunakan one way ANOVA, kemudian dilakukan uji duncan untuk melihat apakah terdapat perbedaan yang sigifikan. Hasil penelitian menunjukkan kadar air sosis analog 52.06-65.2%, abu 1.70-2.00%, lemak 1.26-4.75%, protein 3.10-7.55%, karbohidrat 28.57-34.28%, serat kasar 11.5-22.76%. Analisis fisik pada sosis analog pada tekstur TPA (Texture Profil Analysis) meliputi cohesivenes 0.45, springiness 0.78, chewiness 13.36, hardness 43.45, gumminess 17.84, adhesiveness 0.26 WHC 96.46, OHC 21.22, warna (L*) kecerahan 42.91-70.16, warna (a*) merah-hijau (-)2.41-4.57, warna (b*) kuning-biru 7.17-42.00. Formulasi sosis analog yang disukai panelis adalah sampel F3 (50%:50%) tepung kacang hijau dan tepung sukun adalah 3.37 (agak suka).