bluuebunny/crossref_metadata_2025 huggingface dataset:
MOB GAME
Authors: De Martino Jarryer , Marchesi Senna Mariana , Ribeiro Mapelli Basilio Yulli , Carvalho Fraga Vitor
Published: June 2020

Existe uma necessidade de modificação na metodologia de ensino de projeto de arquitetura. Assim, este artigo apresenta um método sistematizado como estratégia de ensino-aprendizagem na disciplina de projeto de arquitetura, contribuindo para o desenvolvimento da capacidade criativa e de inovação. Os estudantes deixam de solucionar programas de necessidades específicos focados na solução e passam a estruturar um método de projeto a partir da identificação, análise e compreensão dos problemas de projeto. Adquirem habilidades e competências para criar o seu método e adequá-lo a sua realidade mediante aos diferentes programas de necessidades que encontrará no exercício da profissão. Este artigo tem como objetivo apresentar e discutir a contribuição da adoção dos sistemas generativos para o processo de ensino-aprendizagem dos estudantes da disciplina de projeto, na faculdade de Arquitetura e Urbanismo. Para isso é apresentado o processo de criação e aplicação de um sistema generativo formatado como jogo, a fim de ser utilizado como instrumento de projeto, o MOB-Game. Esta pesquisa foi desenvolvida pelos estudantes do programa de pós-graduação de Arquitetura e Urbanismo da Universidade Federal do Espírito Santo, na disciplina de Tópicos Especiais: Sistemas Generativos de Projeto. Como resultado, foi possível discutir sobre o potencial exploratório e investigativo que o método proporciona, incluindo a possibilidade de ele ser utilizado como instrumento para processos de projeto colaborativo e participativo.
The Scope of 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one (DHA)
Authors: Ghaith Eslam A. , Zoorob Hanafi H. , Ibrahim Mona E. , Sawamura Masaya , Hamama Wafaa S.
Published: June 2020

The following review article provides an overview of DHA chemistry, with specific
confirmation based on major historical developments and progress mainly made over
the last two decenniums. It is our hope this review serves as a valuable treasure to those
interested in the 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one (DHA) chemistry, and helps
impact future advancements.
Selective Targeted Drug Delivery Mechanism via Molecular Imprinted Polymers in Cancer Therapeutics
Authors: Suravajhala Renuka , Burri Harshavardhan Reddy , Malik Babita
Published: June 2020

Artificial receptor-like structures such as molecular imprinted polymers (MIPs) are
biomimetic molecules are used to replicate target specific antibody-antigen mechanism. In MIPs, selective
binding of template molecule can be significantly correlated with lock and key mechanism, which
play a major role in the drug delivery mechanism. The MIPs are biocompatible with high efficiency and
are considered in several drug delivery and biosensor applications besides continuous and controlled
drug release leading to better therapeutics. There is a need to explore the potential synthetic methods to
improve MIPs with respect to the imprinting capacity in cancer therapeutics. In this review, we focus on
MIPs as drug delivery mechanism in cancer and the challenges related to their synthesis and applications.
Digitizing the Pharma Neurons – A Technological Operation in Progress!
Authors: Bhardwaj Payal , Yadav Raj Kumar , Kurian Sojan
Published: June 2020

Background:

Digitization and automation are the buzzwords in clinical research and
pharma companies are investigating heavily here. Right from drug discovery to personalized
medicine, digital patients and patient engagement, there is great consideration of technology at
each step.

Methods:

The published data and online information available is reviewed to give an overview of
digitization in pharma, across the drug development cycle, industry collaborations and innovations.
The regulatory guidelines, innovative collaborations across industry, academics and thought leadership
are presented. Also included are some ideas, suggestions, way forwards while digitizing the
pharma neurons, the regulatory stand, benefits and challenges.

Results:

The innovations range from discovering personalized medicine to conducting virtual clinical
trials, and maximizing data collection from the real-world experience. To address the increasing
demand for the real-world data and the needs of tech-savvy patients, the innovations are shaping
up accordingly. Pharma companies are collaborating with academics and they are co-innovating
the technology for example Massachusetts Institute of Technology’s program. This focuses on
the modernization of clinical trials, strategic use of artificial intelligence and machine learning using
real-world evidence, assess the risk-benefit ratio of deploying digital analytics in medicine, and
proactively identifying the solutions.

Conclusions:

With unfolding data on the impact of science and technology amalgamation, we need
shared mindset between data scientists and medical professionals to maximize the utility of enormous
health and medical data. To tackle this efficiently, there is a need of cross-collaboration and
education, and align with ethical and regulatory requirements. A perfect blend of industry, regulatory,
and academia will ensure successful digitization of pharma neurons.
Multiple Autoimmune Syndrome: An Unusual Combination of Autoimmune Disorders
Authors: Sarfaraz Sabahat , Anis Sabiha
Published: June 2020

Background:

Autoimmune diseases are multifactorial with environmental and heritable
factors. Autoimmunity reflects an altered immune status, therefore the presence of more than one
disorder is not uncommon. The coexistence of three or more autoimmune diseases in a patient constitutes
multiple autoimmune syndrome (MAS). This is an interesting case of a middle-aged female
who had celiac disease, primary biliary cholangitis, autoimmune hepatitis and evolving CREST
(Calcinosis, Rhaynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly and Telangiectasia)
syndrome.

Case Report:

Fifty years old female patient presented with generalized fatigue, fever, weight loss,
vertigo and constipation. She was a diagnosed case of celiac disease, and responded well to glutenfree
diet. Family history was unremarkable for any autoimmune disorder. Laboratory workup
showed normal complete blood counts, markedly elevated transaminases and alkaline phosphates.
Her antinuclear antibodies (ANA) test was strongly positive (>1:320) and showed an anti-centromere
pattern. Anti-extractable nuclear antibody(ENA) assay showed anti-mitochondrial and anti-
CENP B antibodies. Liver biopsy revealed overlap syndrome (primary biliary cholangitis and autoimmune
hepatitis).

:

This patient had celiac disease, primary biliary cholangitis and autoimmune hepatitis. Extensive immunological
workup unexpectedly revealed the presence of anti-centromere protein B (anti-CENP
B) antibodies which are strongly associated with CREST syndrome. Clinical re-evaluation of the
patient gave clues of the evolving CREST syndrome. This case report highlights the importance of
adequate immunological investigations in conjunction with clinical information for adequate patient
management to achieve favorable consequences in the future.

Conclusion:

Patients suffering from an autoimmune disease need special attention as multiple immune-
mediated disorders may be present simultaneously or sequentially during the course of the
disease process. MAS patients are at a higher risk of acquiring infections and tumor development
due to prolonged use of immunosuppressants. These patients need close surveillance for the development
of another autoimmune disease, so as to control the current disease and to prevent future
complications. This case report emphasizes the importance of a multidisciplinary team approach including
an immunologist who may facilitate a better understanding of disorders related to the breakdown
of immune tolerance.
Miracles of Herbal Phytomedicines in Treatment of Skin Disorders: Natural Healthcare Perspective
Authors: Ahuja Ashima , Gupta Jitendra , Gupta Reena
Published: June 2020

Human skin is considered as the first line of defense and barrier against the majority of
infections caused through the skin that affect humans. Healthy skin promotes a healthy body that
can be achieved with the usage of modern, allopathic and natural remedies. Major skin ailments affecting
humans are skin cancers, eczema, herpes infection, fungal infection, anti-aging, itching, insect
bites, pemphigus vulgaris, trauma, psoriasis, athlete’s foot infections, rashes, skin pigmentation,
acne, major and minor wound infections that are slowly becoming a burden on health care.
Skin infections can be treated from sources that originate from animals and plants. In spite of advancements
in science and technology, the emergence of natural herbal remedies for managing
skin disorders has become a pivotal and essential contributor in treating skin infections due to increased
demand for herbals and their lower price, and continuous adverse effects of modern
medicines. In the recent era, herbal extracts and their phytomedicines have made a vital contribution
to human health care. Herbal products nowadays are considered as a single line of treatment
for many diseases like Cancers, Diabetes, Cardiovascular and Brain disorders, thereby creating
awareness regarding purity, efficacy and safety of herbal medicines for health care management.
Many therapeutically active natural herbal resources like Aloe, Neem, Liquorice, Tulsi, Amla, Papaya,
Ginger and Eucalyptus are potent and safe in the treatment of dermatological infections. This
review article summarizes the significance of herbal plants for protecting, treating and minimizing
skin infections through the utility of herbal pharmaceuticals like creams, decocted extracts, poultice,
paste and lotions that aid in the treatment of skin infections and diseases at a relatively lower
cost with lesser side effects as compared to modern and allopathic medicines.
Mining the Proteome of Streptococcus mutans for Putative Drug Targets
Authors: Marimuthu Shakti Chandra Vadhana , Ravinarayanan Haribalaganesh , Rosy Joseph Christina , Sundar Krishnan
Published: June 2020

Background:

Dental caries is the most common and one of the prevalent diseases in the world. Streptococcus
mutans is one of the major oral pathogen that causes dental caries by forming biofilm on dental tissues, degrading dental
enamel and consequent cavitation in the tissue. In vitro selection of drug targets is a laborious and expensive process and
therefore computational methods are preferable for target identification at initial stage.

Objective:

The present research aims to find new drug targets in S. mutans by using subtractive proteomics analysis which
implements various bioinformatics tools and databases.

Methods:

The proteome of S. mutans UA159 was mined for novel drug targets using computational tools and databases
such as: CD-HIT, BLASTP, DEG, KAAS and CELL2GO.

Results:

Out of 1953 proteins of S. mutans UA159, proteins that are non-redundant, non-homologous to human and nonessential to the pathogen were eliminated. Around 178 proteins already available in drug target repositories were also eliminated. Possible functions and subcellular localization of 32 uncharacterized proteins were predicted. Substantially 13 proteins were identified as novel drug targets in S. mutans UA159 that can be targeted by various drugs against dental caries.

Conclusion:

This study will effectuate the development of novel therapeutic agents against dental carries and other Streptococcal infections.
Artificial Neural Networks in Cardiovascular Diseases and its Potential for Clinical Application in Molecular Imaging
Authors: Laudicella Riccardo , Comelli Albert , Stefano Alessandro , Szostek Monika , Crocè Ludovica , Vento Antonio , Spataro Alessandro , Comis Alessio Danilo , La Torre Flavia , Gaeta Michele , Baldari Sergio , Alongi Pierpaolo
Published: June 2020

In medical imaging, Artificial Intelligence is described as the ability of a system to properly
interpret and learn from external data, acquiring knowledge to achieve specific goals and tasks
through flexible adaptation. The number of possible applications of Artificial Intelligence is also
huge in clinical medicine and cardiovascular diseases. To describe for the first time in literature,
the main results of articles about Artificial Intelligence potential for clinical applications in molecular
imaging techniques, and to describe its advancements in cardiovascular diseases assessed with
nuclear medicine imaging modalities. A comprehensive search strategy was used based on SCOPUS
and PubMed databases. From all studies published in English, we selected the most relevant
articles that evaluated the technological insights of AI in nuclear cardiology applications. Artificial
Intelligence may improve patient care in many different fields, from the semi-automatization of the
medical work, through the technical aspect of image preparation, interpretation, the calculation of
additional factors based on data obtained during scanning, to the prognostic prediction and risk--
group selection. Myocardial implementation of Artificial Intelligence algorithms in nuclear cardiology
can improve and facilitate the diagnostic and predictive process, and global patient care. Building
large databases containing clinical and image data is a first but essential step to create and train
automated diagnostic/prognostic models able to help the clinicians to make unbiased and faster decisions
for precision healthcare.
Gender and the Digital Divide Across Urban Slums of New Delhi, India: Cross-Sectional Study (Preprint)
Authors: Joshi Ashish , Malhotra Bhavya , Amadi Chioma , Loomba Menka , Misra Archa , Sharma Shruti , Arora Arushi , Amatya Jaya
Published: June 2020

BACKGROUND

Disparities in access to specific technologies within gender groups have not been investigated. Slum settings provide an ideal population to investigate the contributing factors to these disparities.

OBJECTIVE

This study aimed to examine gender differences in mobile phone ownership, internet access, and knowledge of SMS text messaging among males and females living in urban slum settings.

METHODS

A convenience sampling approach was used in sample selection from 675 unnotified slums. A total of 38 slum sites were then selected across four geographic zones. Of these, 10% of the households in each slum site was selected from each zone. One household member was interviewed based on their availability and fulfillment of the eligibility criteria. Eligible individuals included those aged 18 years and above, residing in these slums, and who provided voluntary consent to participate in the study. Individuals with mental or physical challenges were excluded from the study.

RESULTS

Our results showed that females were half as likely to own mobile phones compared with males (odds ratio [OR] 0.53, 95% CI 0.37-0.76), less likely to have internet access (OR 0.79, 95% CI 0.56-1.11), or know how to send text messages (OR 0.93, 95% CI 0.66-1.31). The predictors of mobile phone ownership, internet access, and text messaging between males and females included age, individual education, housing type, and the number of earning members in a household in the adjusted analysis. Among males, the number of earning members was a predictor of both mobile phone ownership and text messaging, whereas household education was a predictor of both internet access and text messaging. Age and individual education only predicted internet access, whereas housing type only predicted text messaging. Among females, household education was a predictor of all the technology outcomes. Age and type of toilet facility only predicted mobile phone ownership; housing type only predicted internet access whereas television ownership with satellite service and smoking behavior only predicted text messaging.

CONCLUSIONS

Our study findings showing disparate access to technology within gender groups lend support for further research to examine the causal mechanisms promoting these differences to proffer significant solutions. Specifically, our study findings suggest that improving household education is crucial to address the disparate access and usage of mobile phones, the internet, and text messaging among women in slum settings. This suggestion is due to the consistency in household educational level as a predictor across all these technology indicators. In addition, the mechanisms by which the number of household earning members influences the disparate access to technology among men call for further exploration.
COVID-19 and the Gendered Use of Emojis on Twitter: Infodemiology Study (Preprint)
Authors: Al-Rawi Ahmed , Siddiqi Maliha , Morgan Rosemary , Vandan Nimisha , Smith Julia , Wenham Clare
Published: June 2020

BACKGROUND

The online discussion around the COVID-19 pandemic is multifaceted, and it is important to examine the different ways by which online users express themselves. Since emojis are used as effective vehicles to convey ideas and sentiments, they can offer important insight into the public’s gendered discourses about the pandemic.

OBJECTIVE

This study aims at exploring how people of different genders (eg, men, women, and sex and gender minorities) are discussed in relation to COVID-19 through the study of Twitter emojis.

METHODS

We collected over 50 million tweets referencing the hashtags #Covid-19 and #Covid19 for a period of more than 2 months in early 2020. Using a mixed method, we extracted three data sets containing tweets that reference men, women, and sexual and gender minorities, and we then analyzed emoji use along each gender category. We identified five major themes in our analysis including morbidity fears, health concerns, employment and financial issues, praise for frontline workers, and unique gendered emoji use. The top 600 emojis were manually classified based on their sentiment, indicating how positive, negative, or neutral each emoji is and studying their use frequencies.

RESULTS

The findings indicate that the majority of emojis are overwhelmingly positive in nature along the different genders, but sexual and gender minorities, and to a lesser extent women, are discussed more negatively than men. There were also many differences alongside discourses of men, women, and gender minorities when certain topics were discussed, such as death, financial and employment matters, gratitude, and health care, and several unique gendered emojis were used to express specific issues like community support.

CONCLUSIONS

Emoji research can shed light on the gendered impacts of COVID-19, offering researchers an important source of information on health crises as they happen in real time.
Hospital Epidemics Tracker (HEpiTracker): Description and pilot study of a mobile app to track COVID-19 in hospital workers (Preprint)
Authors: Soriano Joan B , Fernández Esteve , de Astorza Álvaro , Pérez de Llano Luis A , Fernández-Villar Alberto , Carnicer-Pont Dolors , Alcázar-Navarrete Bernardino , García Arturo , Morales Aurelio , Lobo María , Maroto Marcos , Ferreras Eloy , Soriano Cecilia , Del Rio-Bermudez Carlos , Vega-Piris Lorena , Basagaña Xavier , Muncunill Josep , Cosio Borja G , Lumbreras Sara , Catalina Carlos , Alzaga José María , Gómez Quilón David , Valdivia Carlos Alberto , de Lara Celia , Ancochea Julio
Published: June 2020

BACKGROUND

Hospital workers have been the most frequently and severely affected professional group during the COVID-19 pandemic, and have a big impact on transmission. In this context, innovative tools are required to measure the symptoms compatible with COVID-19, the spread of infection, and testing capabilities within hospitals in real time.

OBJECTIVE

We aimed to develop and test an effective and user-friendly tool to identify and track symptoms compatible with COVID-19 in hospital workers.

METHODS

We developed and pilot tested Hospital Epidemics Tracker (HEpiTracker), a newly designed app to track the spread of COVID-19 among hospital workers. Hospital staff in 9 hospital centers across 5 Spanish regions (Andalusia, Balearics, Catalonia, Galicia, and Madrid) were invited to download the app on their phones and to register their daily body temperature, COVID-19–compatible symptoms, and general health score, as well as any polymerase chain reaction and serological test results.

RESULTS

A total of 477 hospital staff participated in the study between April 8 and June 2, 2020. Of note, both health-related (n=329) and non–health-related (n=148) professionals participated in the study; over two-thirds of participants (68.8%) were health workers (43.4% physicians and 25.4% nurses), while the proportion of non–health-related workers by center ranged from 40% to 85%. Most participants were female (n=323, 67.5%), with a mean age of 45.4 years (SD 10.6). Regarding smoking habits, 13.0% and 34.2% of participants were current or former smokers, respectively. The daily reporting of symptoms was highly variable across participating hospitals; although we observed a decline in adherence after an initial participation peak in some hospitals, other sites were characterized by low participation rates throughout the study period.

CONCLUSIONS

HEpiTracker is an already available tool to monitor COVID-19 and other infectious diseases in hospital workers. This tool has already been tested in real conditions. HEpiTracker is available in Spanish, Portuguese, and English. It has the potential to become a customized asset to be used in future COVID-19 pandemic waves and other environments.

CLINICALTRIAL

ClinicalTrials.gov NCT04326400; https://clinicaltrials.gov/ct2/show/NCT04326400
Kritik terhadap Penggunaan IQ dalam Diagnosis Kesulitan Belajar Spesifik
Authors: Wibowo Satrio Budi , Azwar Saifuddin , Adiyanti Maria Goretti , Wimbarti Supra
Published: June 2020

Kesulitan belajar spesifik sering didefinisikan sebagai pencapaian rendah yang tidak terduga. Berdasarkan konsep mengenai pencapaian rendah yang tidak terduga, model kesenjangan digunakan dalam upaya mendiagnosis kesulitan belajar spesifik. Menurut model kesenjangan, diagnosis kesulitan belajar spesifik dapat ditegakkan setelah ditemukan adanya perbedaan antara IQ dan prestasi. Namun, dalam beberapa tahun terakhir, para peneliti mempertanyakan validitas model kesenjangan dalam mendiagnosis SLD. Beberapa penelitian menyimpulkan bahwa penggunaan IQ dalam mendiagnosis SLD tidak diperlukan. Jadi kriteria diagnostik SLD dalam beberapa pedoman internasional direvisi. Salah satu manual diagnostik yang direvisi adalah Manual Diagnostik dan Statistik Gangguan Mental (DSM). Kriteria dan diagnosis tentang kesulitan belajar spesifik telah berubah, di mana model kesenjangan tidak digunakan. Makalah ini berupaya menjelaskan berbagai argumen yang mematahkan konsep model kesenjangan, sehingga penggunaan tes kecerdasan tidak lagi diperlukan dalam menegakkan diagnosis kesulitan belajar spesifik.
Between Street Demonstrations and Ballot Box: Tenure Rights, Elections, and Social Movements among the Urban Poor in Jakarta
Authors: Amalinda Savirani  , Guntoro
Published: June 2020

This article investigates the political participation of urban poor through the People's Network of Urban Poor (Jaringan Rakyat Miskin Kota, JRMK) in Jakarta's 2017 gubernatorial election. It also traces the material aspects of this movement, particularly the issues emphasised by the movement: settlement rights, tenure rights, and livelihood rights. Settlement rights reflect a complex system of agrarian laws in Indonesia, and urban development plans in Jakarta, all of which have been shaped by the contestation of economic and political interests. Tenure and livelihood rights for the urban poor,  are heavily steeped in history, with constant threat of forced eviction, As a result the three rights became increasingly tangible and movement became ever more urgent. This article argues that the materiality of social movements influences the urban poor movement political strategies. In this case, the movement created a "political contract" with the candidate who ultimately emerged victorious in the election; owing to the complexity of land and settlement issues, electoral politics offered the most promising strategy. However, movements with different types of 'materiality' could employ other approaches.
PAGO POR SERVICIOS AMBIENTALES (ECOSISTÉMICOS) EN MÉXICO ¿UNA ALTERNATIVA PARA LA CONSERVACIÓN DE LA BIODIVERSIDAD Y EL DESARROLLO?
Authors: Macip-Ríos Rodrígo , Francisco Macip Ricardo
Published: June 2020

Los esquemas de pagos por servicios ambientales (PSA) se consideran como el paradigma
actual en la biología de la conservación. Los PSA plantean la conservación de la biodiversidad,
la reducción de la pobreza y el desarrollo en un mismo paquete metodológico. En México los
PSA están regulados por las dependencias federales, estatales y locales y ocupan una superficie
de 3,080,500 hectáreas del territorio nacional, de la cual 2,325,400 hectáreas proveen servicios
ambientales hídricos y 755,100 hectáreas servicios ambientales derivados de la biodiversidad.
La efectividad del esquema de PSA estará en duda hasta que se compruebe su efecto directo o
indirecto en la reducción de la pobreza y el incremento de los índices de desarrollo, donde los
esquemas de PSA deberán estar completamente democratizados y libres de cualquier uso
político y clientelar. Un análisis preliminar entre el índice de desarrollo humano (IDH) a una
escala nacional y estatal muestran una relación negativa entre los PSA y el IDH, sin embargo un
enfoque a un nivel local o microrregionales es necesario para generar conclusiones más
precisas. Lo cierto es que como herramienta de conservación los esquemas de PSA en México
deben considerarse aún en proceso experimental o de prueba.
¿CO-EVOLUCIÓN MORFOLÓGICA ENTRE LOS PICOS DE LOS COLIBRÍES Y LAS COROLAS DE LAS PLANTAS?
Authors: Burbano-Álvarez Jorge Eduardo
Published: June 2020

In studies of the hummingbird-plant interaction the researchers have observed a pattern in
which these organisms seem to be associated according to the morphological adjustment
between hummingbird´s peaks and plant´s corollas, and is believed to be the result of
morphology co-evolution between these structures, but, certain facts not consistent with this
idea could lead to another interpretation of the phenomenon. I propose a diferent idea through
analysis from: the morphological and ecological generalism in the interaction, and the
importance of nectar for hummingbirds, phenomena that could explain the pattern. Probably
the morphology of hummingbird´s peak and plant´s corollas have different causes to the
interaction.
ASPECTOS POBLACIONALES DE CARDISOMA CRASSUM SMITH, 1870 (DECAPODA: GECARCINIDAE) EN EL ESTERO EL SALADO, PUERTO VALLARTA, JALISCO, MEXICO
Authors: Matamoros-Contreras Elías
Published: June 2020

Se establecieron cuadrantes en el estero El Salado, Puerto Vallarta, Jalisco, México. Se cubrió un
área de 1200 m2, se contaron 1939 madrigueras de C. Crassum; la densidad promedio fue 1.66
madrigueras/m2 y el diámetro promedio fue 4.74 cm. Se construyeron histogramas de
frecuencia. No se encontraron diferencias significativas entre los sitios y los periodos de captura
(densidades y diámetros de las madrigueras). Se observó que las primeras hembras ovígeras
llegan a la playa a desovar la primera semana de julio. En agosto se observaron organismos
pequeños de C. crassum (2.03 cm) en el estuario El Salado, lo que no es común antes de julio. Se
concluyó que a) este es el primer estudio formal de C. crassum que se realiza en el estero El
Salado, b) la densidad de C. crassum en el estuario es alta en comparación con cangrejos de la
misma familia en otros sitios de estudio, c) el periodo de desove inicia la primera semana de
julio, d) la entrada de las madrigueras de C. Crassum es simple y e) existe un total
desconocimiento acerca de la biología de C. crassum.
ANÁLISIS DEL COMPORTAMIENTO ESTACIONAL E INTERANUAL DE LA COMUNIDAD ICTIOFAUNÍSTICA ASOCIADA A ZONAS DE MANGLAR EN LA LAGUNA DE ALVARADO, VERACRUZ
Authors: FRANCO-LÓPEZ JONATHAN
Published: June 2020

Los manglares contribuyen al mantenimiento de los procesos funcionales y productivos de los sistemas costeros, en la actualidad enfrentan presiones antropocéntricas y ambientales que alteran la estructura y ponen en riesgo su desarrollo. Este trabajo se realizó con la finalidad de analizar los parámetros ecológicos de la comunidad ictiofaunística en zonas de manglar de forma estacional e interanual. Los parámetros se registraron en 10 estaciones donde se colectaron los peces con un chinchorro de 50 m., en el período de 1995 a 2012. Los registros ambientales se sometieron a un ANOVA por año. Para evaluar la diversidad y la dominancia entre años, se utilizaron los índices de Shannon-Wiener y de McNaughton. Los datos de abundancia y por año se analizaron mediante un escalamiento multidimensional (MDS). Los parámetros fisicoquímicos muestran diferencias significativas para los años 1995, 1998, 2002 a 2005, 2007 y 2010. Se capturaron 46939 organismos con una biomasa de 604058.8 g., pertenecientes a 82 especies. El efecto de la elevación de temperatura y la variación en las lluvias, ha favorecido la incursión de especies marinas al sistema y en particular a las zonas de manglar incrementando la riqueza específica pero disminuyendo los valores de diversidad y de la equitatividad. La relación entre los cambios ambientales y su efecto sobre la fluctuación en la abundancia de las especies, es un aspecto que debe ser estudiado con la finalidad de predecir los posibles impactos en los aspectos socioeconómicos en el sistema lagunar de Alvarado.
PHENYTOIN SODIUM INDUCED MICRONUCLEI IN THE POLYCHROMATIC ERYTHROCYTES OF CD-1 MOUSE PERIPHERAL BLOOD
Authors: Alarcón-Herrera Norberto , Flores-Maya Saúl
Published: June 2020

Seizures are one of the most common neural disorders, and may be sporadic or recurrent (epilepsy) crisis. In the case of people with epilepsy, these must be treated throughout their lives, being a major phenytoin prescription for seizure control medicines out. However, despite having several decades in the market there is very little information about their genotoxic effects. Therefore in this study to evaluate the ability of phenytoin to induce genotoxic damage for 30 days using the micronucleus test in mice Mus musculus CD-1 strain. It was determined that the three doses of phenytoin used (2.8, 4.2 and 6.64 mg/kg) induced clastogenicity in mouse chromosomes, that at higher doses the damage is greater. Furthermore, also inhibiting cytotoxic damage induced cell kinetics for doses of 4.2 and 6.64 mg/kg.
Aplicativos de Delivery: entrar ou não nesta modalidade? Um estudo no segmento de foodservice voltado para jovens em uma região universitária do interior paulista
Authors: Henrique Daniel Christian , Tincani Gustavo De Oliveira , Paciência Bruno Luiz da
Published: June 2020

O segmento de foodservice imergiu nos anos recentes em grandes mudanças com a disseminação dos aplicativos de delivery. Nesse contexto, esta pesquisa teve o objetivo de averiguar se é preciso ingressar ou não nesta nova modalidade de entrega para obtenção de viabilidade financeira mais atrativa na implantação de um empreendimento no segmento de foodservice focado exclusivamente no atendimento do público jovem (que ainda busca entretenimento e socialização local). Para isto, foram realizadas três análises mutuamente excludentes de um restaurante de Pratos Feitos (PFs) com uso da metodologia de Copeland, Coller e Murrin (2002): uma focada na entrega via pedidos de aplicativos e outras duas apenas com atendimento local, diferenciadas por vertentes noturnas de bar ou pizzaria. Observou-se potencial de alta lucratividade apenas para o Restaurante/DeliveryApp e para o Restaurante/Bar, mas a primeira alternativa com entregas por aplicativos mostrou-se com maiores probabilidades de sua ocorrência para as estimativas otimistas e prováveis. O Restaurante/Pizzaria demonstrou ser muito inferior em atratividade financeira no comparativo entre todos os quesitos. Concluiu-se, para esta pesquisa, que o atendimento local focado no entretenimento de jovens ainda tem potencial de viabilidade financeira competitiva dependendo do segmento foodservice e que o restaurante centrado no uso dos aplicativos denota maiores probabilidades de aumento dos retornos futuros.
REVISÃO SISTEMÁTICA DE ESTUDOS SOBRE SUPPLY CHAIN NO BRASIL
Authors: Archanjo Jander Luiz Silva , Chaib Diana Chaukat , Toledo Vicente Alves , Rezende Marcelo Lacerda
Published: June 2020

: O conceito Supply Chain ou cadeia de suprimentos exprime a ideia de uma rede de empresas independentes que agem em sintonia de forma a construir valor para o usuário final por meio da distribuição de produtos. Diante da importância do tema, este estudo tem o objetivo de realizar uma revisão sistemática de literatura (RSL), no período entre 2012 e 2018, buscando identificar as características das publicações que discorrem sobre as práticas que envolvem Supply Chain no Brasil. Foram analisados 56 artigos e os resultados evidenciam uma média anual de publicação entre 2012 e 2018 de 8 publicações. “Gerenciamento” constituiu a área temática de 67,8% das publicações. O periódico que mais publicou foi a “Revista de Administração de Empresas”. Sobre as abordagens teóricas realizadas pelos autores, se destacaram “Gestão da Cadeia de Suprimentos” e “Desempenho”. Além disso, a cadeia automotiva foi a principal cadeia estudada pelos pesquisadores.
Diagnóstico e Proposta de diretrizes na aplicação do método DMAIC para melhoria das dimensões do Planejamento e Controle da Produção
Authors: Moura Fernanda Marques de , Facin Ana Lúcia Figueiredo , Schleder Adriana Miralles
Published: June 2020

Este trabalho teve como objetivo corroborar para a discussão sobre a utilização de ferramentas da Gestão da Qualidade na melhoria do Planejamento e Controle da Produção (PCP), visando alavancar as diferentes dimensões da competitividade. Buscou-se na literatura estudos que trabalharam com essa integração, focando na utilização de ferramentas associadas ao programa Seis Sigma e mais especificamente ao uso do DMAIC. Com as análises realizadas foi possível criar uma proposta com diretrizes para aplicação do método, com o intuito de mitigar os pontos fracos encontrados e suas possíveis consequências. Esta proposta foi separada em fases, onde em cada uma delas constam atividades sugeridas a serem realizadas, de forma cronológica. Foi possível concluir que há uma relação entre os temas citados e eficácia na utilização dos dois em conjunto. Porém, existe a necessidade de uma abordagem mais profunda a respeito dos possíveis benefícios desta integração.
A Mechanized Proof of a Textbook Type Unification Algorithm
Authors: Rauber Du Bois André , Ribeiro Rodrigo , Amaro Maycon
Published: June 2020

Unification is the core of type inference algorithms for modern functional programming languages, like Haskell and SML. As a first step towards a formalization of a type inference algorithm for such programming languages, we present a formalization in Coq of a type unification algorithm that follows classic algorithms presented in programming language textbooks. We also report on the use of such formalization to build a correct type inference algorithm for the simply typed λ-calculus.
Int-FLBCC: Model for Load Balancing in Cloud Computing using Fuzzy Logic Type-2 and Admissible Orders.
Authors: Schneider Guilherme Bayer , Moura Paz de Moura Bruno , Yamin Adenauer C , Hax Sander Reiser Renata
Published: June 2020

Dynamic consolidation of virtual machines (VMs) is an effective way to improve resource utilization and power efficiency in cloud computing, directly affecting Quality of Service aspects. This paper presents Int-FLBCC, a new proposal with exploring a Type-2 Fuzzy Logic approach to address the uncertainties and inaccuracies in determining resource usage, aiming at energy savings with minimal performance degradation. Validation results in a simulated cloud computing environment showed improvements in energy efficiency of 8.83% with IQR_XY and 22.43% with MAD_XY. For fulfillment of Service Level Agreements (SLA), the best values achieved were 9.06% with MAD_XY and 25% of THR_Lex1.
Reasoning about Partial Correctness Assertions in Isabelle/HOL
Authors: Martini Alfio Ricardo
Published: June 2020

Hoare Logic has a long tradition in formal verification and has been continuously developed and used to verify a broad class of programs, including sequential, object-oriented and concurrent programs. The purpose of this work is to provide a detailed and accessible exposition of the several ways the user can conduct, explore and write proofs of correctness of sequential imperative programs with Hoare logic and the ISABELLE proof assistant. With the proof language Isar, it is possible to write structured, readable proofs that are suitable for human understanding and communication.
Validación de un instrumento para medir satisfacción de usuarios en instituciones educativas del sector privado: ciudad de Xalapa-Enríquez (México)
Authors: Montero-Mora Judith Guadalupe , Cantón-Croda Rosa María
Published: June 2020

RESUMEN:

 

 La satisfacción del cliente es un tema de gran importancia para toda organización que desee lograr una ventaja competitiva, ya que los clientes satisfechos serán fieles a la empresa. Las instituciones educativas no son ajenas a esta realidad. En el contexto empresarial, existen diferentes instrumentos para medir satisfacción de clientes, algunos de uso mundial, que se han adaptado al contexto educativo, como las escalas SERVQUAL y SERVPERF. Existen instrumentos diseñados específicamente para medir la satisfacción de usuarios de instituciones de educación enfocados sólo en universidades públicas y privadas, donde el entrevistado es el usuario directo (estudiante). El objetivo del trabajo fue desarrollar y validar un instrumento para medir satisfacción de usuarios de instituciones educativas del sector privado, aplicable a usuarios indirectos: padres de familia de estudiantes en niveles básicos, a usuarios directos: estudiantes en bachillerato, nivel superior (licenciatura y posgrado) y a capacitación para el trabajo. El diseño y la validación del instrumento se realizaron aplicando el método Delphi en dos rondas, con la participación de 12 expertos. El instrumento final se aplicó a una muestra piloto de 50 usuarios; con esta muestra se validó utilizando el Alfa de Cronbach y se obtuvo un valor de 0,98. El resultado fue un instrumento con 24 ítems, 22 en una escala diferencial semántico con valores de 1 a 7 y dos preguntas abiertas. Se considera que este instrumento es un recurso apropiado que aporta elementos para la planeación de la estrategia de negocio a quienes toman decisiones en el sector educativo privado.
La innovación educativa en América Latina: lineamientos para la formulación de políticas públicas
Authors: Ruiz-Bolivar Carlos , Ríos-Cabrera Pablo
Published: June 2020

El propósito del ensayo consiste en proponer un conjunto de lineamientos para la formulación de políticas públicas orientadas al desarrollo de innovaciones educativas en América Latina, a partir de la exploración de la literatura especializada, para determinar los aspectos críticos del desarrollo de innovaciones en el contexto latinoamericano. Se hizo una selección de los documentos en función de la credibilidad de las fuentes, actualidad y pertinencia de las referencias. En la primera parte del trabajo, se presenta una introducción sobre el problema del desfase en la relación entre sociedad y educación; se analizan también los factores que favorecen u obstaculizan la innovación educativa; la innovación educativa en América Latina y sus tendencias. En la segunda parte, se proponen los siguientes lineamientos: construir consensos, asumir una visión sistémica y contextualizada, valorar a los educadores, trabajar en comunidades de aprendizaje y aprovechar las tecnologías de información y comunicación. Se espera que estos lineamientos sirvan para: (a) formular políticas que orienten y favorezcan los cambios en educación; (b) planificar, desarrollar y evaluar las innovaciones de una manera más sistemática, eficiente y científica; y (c) contribuir a generar una cultura de la innovación educativa en América Latina.
Autonomía universitaria y libertad de cátedra en tiempos de cambio
Authors: Campos-Céspedes Jensy , Solano-Gutiérrez Walter
Published: June 2020

Se ofrece una discusión sobre los conceptos de autonomía universitaria y la libertad de cátedra, a la luz de su necesaria reconceptualización en las actuales sociedades, caracterizadas por la obsolescencia del conocimiento y la desconfiguración de los grandes relatos que estructuraban los discursos y quehaceres de las instituciones universitarias de antaño.  La virtualización, la emergencia de la figura de prosumidores y el desarrollo de las tecnologías de la información y la comunicación, entre otros avances, demanda una reconfiguración de las instituciones universitarias en cuanto a lo que tradicionalmente se ha concebido como libertad de cátedra y autonomía universitaria.
Percepciones de las personas docentes para el mejoramiento de la mediación pedagógica en el uso de videoconferencias en la Universidad Estatal a Distancia (UNED)
Authors: Salas-González Silvia
Published: June 2020

El artículo analiza la importancia de que quienes imparten videoconferencias en la Universidad Estatal a Distancia (UNED) sean conscientes de la necesidad de replantearse las estrategias metodológicas propuestas por ellos en el desarrollo de cada una de las sesiones programadas. Por ende, la investigación cumple por objetivo diseñar una propuesta de videoconferencia como recurso para la mediación pedagógica, la cual las personas docentes puedan consultar e implementar en su respectiva planificación. Para tal efecto, el marco teórico se sustentó en la investigación-acción de tipo cooperativa y colaborativa, en la cual se realiza un trabajo conjunto entre investigadores y docentes. El hallazgo principal demuestra la necesidad que manifiestan las personas docentes acerca de recibir procesos de inducción y capacitaciones para planificar y mediar adecuadamente las videoconferencias. Igualmente, que es preciso contar con una guía amplia de elementos técnicos y estrategias pedagógicas útiles para presentar en forma atractiva las temáticas en estudio.
Consequences of cultural practices on advertising: Rethinking the role of individual’s values versus social norms for cross-cultural research
Authors: Saleem Salman
Published: June 2020

The study has contributed to the current debate on the significance of cultural referenced practices over self-reported values in the identification of culture (e.g., Fischer & Schwartz, 2011; Kirkman, Lowe, & Gibson, 2017). The study has examined whether there is a difference in the self-reported values versus cultural-referenced practices concerning masculinity and power distance. Also, which facet of masculinity and power distance, i.e., self-referenced and/or cultural referenced ratings predict the manifestation of such values in the advertising. The study has used a survey method and ask 200 respondents to report masculinity and power distance in their individual behavioural preference, in their social context and the manifestation of masculinity and power distance in advertising. The results show that self-reported and cultural-referenced rating of masculinity and power distance differ significantly. Moreover, the regression analysis shows that the culture-referenced masculinity and power distance predicts the reflection of respective values in advertising, but no such effect of self-reported values are found. Obtained results strengthen the argument that self-reported values did not identify the culture, instead, the normative values did identify the culture. Future international business and cross-cultural corporate governance research should consider the cultural practices of masculinity and power in their cross-cultural investigation.
METHODS OF INDIVIDUAL TRAINING OF ENGINEERING PERSONNEL IN THE CONDITIONS OF DIGITALIZATION OF EDUCATION
Authors: Попов Андрей Иванович , Майстренко Наталья Владимировна , Букин Александр Александрович
Published: June 2020

Проанализированы различные формы освоения образовательной профессиональной программы, показана востребованность обучения по индивидуальному учебному плану и исследованы особенности контингента обучающихся. Обоснована важность развития универсальных компетенций и выделены ключевые из них в контексте подготовки к инновационной деятельности. Сформулированы психолого-педагогические условия эффективной подготовки технических специалистов по заочной форме. Описан организационный механизм индивидуализации обучения в цифровом пространстве на основе компетентностного профиля.

Various forms of mastering the educational professional program are analyzed, the advantages and disadvantages of self-education in the digital space and distance learning are considered. The article shows the demand for training according to an individual curriculum and examines the features of the contingent of students that cause the problem of developing a special methodology for their individual training for activities in the conditions of the emerging innovative economy. The author substantiates the importance of developing universal competencies, including a cluster of creative professional competencies, readiness to work in conditions of psychological stress, digital literacy, mathematical analytical thinking, and spiritual and moral qualities. Psychological and pedagogical conditions for effective training of technical specialists by correspondence are formulated, which assume consideration of the needs of participants in the educational process, cognitive abilities and competence profile. It is proposed to use impulse educational technologies, adaptive management of the process of students’ development and intensification of independent work in the digital space. Special attention is paid to the need to strengthen education in order to prepare for engineering creativity. It is advisable to design a personal educational track with the help of a tutor. The organizational mechanism of individualization of training in the digital space based on the competence profile is described. At the first level of individualization, an individual plan is developed. At the second level, on the basis of a digital competence profile, students’ educational activities are managed during the semester. The organization of individual training of technical specialists in correspondence form with the maximum use of the potential of digitalization of education will improve the quality of education and provide an advanced level of formation of the competencies demanded by the customer, to achieve a more complete satisfaction of students with the educational services provided.
Comportamiento electroquímico de los aceros 316L, 316L nitrurado y F1586 en fluido corporal simulado
Authors: Galeano Osorio Diana Shirley
Published: June 2020

Los materiales metálicos se emplean con frecuencia en la fabricación de implantes biomédicos, siendo la corrosión un factor que determina el éxito del desempeño del implante en el organismo. Debido a esto, la presente investigación estudió el comportamiento electroquímico de los aceros 316L, 316L nitrurado y F1586 en fluido corporal simulado. A través de difracción de rayos X fue posible deducir que las capas nitruradas estaban compuestas, además de la fase austenítica, de la fase S. De acuerdo a los resultados alcanzados mediante análisis electroquímicos, la capa pasiva de los aceros 316L nitrurado y F1586 fueron las más protectoras en comparación al acero 316L sin nitrurar. Esto se debió a la alta estabilidad de la capa pasiva del acero nitrurado y a la posible formación de productos estables de corrosión en la superficie del acero F1586. En términos generales, el acero sometido a nitruración reveló la menor corrosión en el fluido corporal simulado.