bluuebunny/crossref_metadata_2025 huggingface dataset:
ONTOLOGICAL AND POLITICAL DIMENSIONS OF REFLECTION ON RISK: RISK SOCIETY AND DIGITALIZATION
Authors:   St. Petersburg State University, NIKIFOROV ALEXANDER
Published: March 2023

Given publication raises the question of the role of reflection on risk in the formation of political space and relations of various actors. The author starts from the Hobbesian problem of the social order to define the role of the state in the formation of the space of certainty/security. For this purpose reflection on risk is considered as an ontological principle, that allows political subjects to create a boundary between stabilized knowledge as a valid present and uncertainty as an area of the future with multiple outcomes. The analysis determines various theoretical implications and concepts as a way for understanding the mechanisms of reflection on risk in the practices of various political actors and their relationships (state institutions, social movements, citizens, etc.). In this regard, the author considers the paradigm of cosmopolitanism to determine the possibilities to explore political dimension of risk. The analysis of specific events such as public conflicts and catastrophes makes it possible to identify the limitations of risk control imposed by the state and to determine the level of mass consciousness as a space and a source of multiple risk reflection, which is new could be related with contemporary political populism, irrationality and the actualization of conspiracy narratives as one of the ways to identify and stabilize perceived group or individual risks. The processes of digitalization themselves are considered as a way to reduce risk by managing it through the determination of attributes/characteristics of objects. On the other hand, digital communication is defined as a new way of existence of publicity, expanding opportunities for reflexivity due to the universal connectivity and fragmentation of audiences united by the perception of risk. This determines the possibilities for evaluation of the deflation of governance as risk/knowledge management and the degree of the gap in risk perception among various actors.
Cyclophilin D-mediated Mitochondrial Permeability Transition Regulates Mitochondrial
Function
Authors: Zhou Shaoyun , Yu Qinwei , Zhang Luyong , Jiang Zhenzhou
Published: March 2023

Background:

Mitochondria are multifunctional organelles, which participate in biochemical processes.
Mitochondria act as primary energy producers and biosynthetic centers of cells, which are involved in oxidative
stress responses and cell signaling transduction. Among numerous potential mechanisms of mitochondrial
dysfunction, the opening of the mitochondrial permeability transition pore (mPTP) is a major determinant of mitochondrial
dysfunction to induce cellular damage or death. A plenty of studies have provided evidence that the
abnormal opening of mPTP induces the loss of mitochondrial membrane potential, the impairment calcium
homeostasis and the decrease of ATP production. Cyclophilin D (CypD), localized in the mitochondrial transition
pore, is a mitochondrial chaperone that has been regarded as a prominent mediator of mPTP.

Methods:

This review describes the relationship between CypD, mPTP, and CypD-mPTP inhibitors through
systematic investigation of recent relevant literature.

Results:

Here, we have highlighted that inhibiting the activity of CypD protects models of some diseases, including
ischaemia/reperfusion injury (IRI), neurodegenerative disorders and so on. Knockdown studies have demonstrated
that CypD possibly is mediated by its peptidyl-prolyl cis-trans isomerase activity, while the primary
targets of CypD remain obscure. The target of CypD-mPTP inhibitor can alleviate mPTP opening-induced cell
death. The present review is focused on the role of CypD as a prominent mediator of the mPTP, further providing
insight into the physiological function of mPTP and its regulation by CypD.

Conclusion:

Blocking the opening of mPTP by inhibiting CypD might be a new promising approach for suppressing
cell death, which will suggest novel therapeutic approaches for mitochondria-related diseases.
Safety and Efficacy of Genistein in Sanfilippo Syndrome - A Systematic
Review
Authors: Majid Haya , Masoom Md. , Khan Mohd. Ashif , Garg Aakriti
Published: March 2023

Background:

Sanfilippo syndrome, commonly known as mucopolysaccharidosis type III
(MPS III), is a rare autosomal recessive lysosomal storage disease that primarily affects the brain and
spinal cord. It is caused by a deficiency of enzymes involved in the catabolism of glycosaminoglycan
(GAG) and heparin sulfate (HS). Although Genistein has been presented as a potential therapeutic, its
safety and efficacy for the treatment of Sanfilippo syndrome are not well established.

Objective:

This systematic review aims to evaluate the safety and efficacy of Genistein with a primary
endpoint of providing an inference whether the medication is producing any improvements when administered
in patients suffering from Sanfilippo syndrome.

Methods:

An intensive computerized literature search was performed according to PRISMA guidelines
in major databases such as PubMed, ScienceDirect, Embase, Science Citation Index Expanded,
The Cochrane Library, and Web of Science until 30 April 2022. Studies evaluating the efficacy and
safety of genistein in patients with Sanfilippo Syndrome were included. The quality of the included
studies was assessed using the New Castle Ottawa Scale.

Results:

A total of 558 studies were identified in the initial search. After removing duplicates, 25 studies
were screened based on title and abstract, of which 06 studies were included in this systematic review.
Among them, 02 studies were of high quality and 04 studies were of moderate quality. After
administration of genistein, a decrease in urinary GAG levels and HS levels was observed.

Conclusion:

Based on the limited evidence present in the literature, this systematic review suggests
that genistein can be safely used to treat Sanfilippo syndrome as it lowers GAG levels. However, data
on the long-term benefit profile of genistein and high-quality evidence are still needed as a conclusive
result could not be withdrawn.
Corneal Epithelial Development and the Role of Induced Pluripotent Stem
Cells for Regeneration
Authors: Selvarajah Komathi , Tan Jun Jie , Shaharuddin Bakiah
Published: March 2023

Severe corneal disorders due to infective aetiologies, trauma, chemical injuries, and chronic
cicatricial inflammations, are among vision-threatening pathologies leading to permanent corneal scarring.
The whole cornea or lamellar corneal transplantation is often used as a last resort to restore vision.
However, limited autologous tissue sources and potential adverse post-allotransplantation sequalae urge
the need for more robust and strategic alternatives. Contemporary management using cultivated corneal
epithelial transplantation has paved the way for utilizing stem cells as a regenerative potential. Humaninduced
pluripotent stem cells (hiPSCs) can generate ectodermal progenitors and potentially be used for
ocular surface regeneration. This review summarizes the process of corneal morphogenesis and the signaling
pathways underlying the development of corneal epithelium, which is key to translating the maturation
and differentiation process of hiPSCs in vitro. The current state of knowledge and methodology for
driving efficient corneal epithelial cell differentiation from pluripotent stem cells are highlighted.
Oil Extraction of Skeletonema costatum Microalgae with the Assistance of Ultrasonic Waves
Authors:   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Negeri Semarang, Rengga Wara Dyah Pita , Prayoga Ade Bintang ,   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Negeri Semarang, Asnafi Agus ,   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Negeri Semarang, Triwibowo Bayu ,   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Negeri Semarang
Published: March 2023

In the current conditions, the amount of petroleum is running low, so that new alternative energy is needed to support the availability of fuel oil in Indonesia. One such alternative energy is biodiesel, which is liquid fuel for diesel motors from plants or animals. Making this biodiesel needs raw materials in the form of oil. The oil used in this study is the Skeletonema costatum microalgae oil available in Jepara. Oil extraction is carried out utilizing dried microalgae then extracted with the help of ultrasonic waves. The extraction temperature used was 50, 60, 70, 80 ° C for 60, 120, 180 minutes and using hexane solvents. The results showed that the longer the extraction time according to the contraction temperature which was close to the boiling point of hexane showed an increase in the amount of microalgae oil produced. The extracted microalgae oil yield obtained optimally at 70oC for 180 minutes was 18.44%. The dominant microalgae oil content is palmitic acid as much as 74.48%, followed by oleic acid as much as 7.21%.
Violent knights in violent times
Authors: Sherer Idan
Published: March 2023

Review of Samuel A. Claussen, Chivalry and violence in late medieval Castile (Woodbridge: The Boydell Press, 2020, x + 231 pp., ill., index)
The Effectiveness of Wearable Devices Using Artificial Intelligence for Blood Glucose Level Forecasting or Prediction: Systematic Review
Authors: Ahmed Arfan , Aziz Sarah , Abd-alrazaq Alaa , Farooq Faisal , Househ Mowafa , Sheikh Javaid
Published: March 2023

Background

In 2021 alone, diabetes mellitus, a metabolic disorder primarily characterized by abnormally high blood glucose (BG) levels, affected 537 million people globally, and over 6 million deaths were reported. The use of noninvasive technologies, such as wearable devices (WDs), to regulate and monitor BG in people with diabetes is a relatively new concept and yet in its infancy. Noninvasive WDs coupled with machine learning (ML) techniques have the potential to understand and conclude meaningful information from the gathered data and provide clinically meaningful advanced analytics for the purpose of forecasting or prediction.

Objective

The purpose of this study is to provide a systematic review complete with a quality assessment looking at diabetes effectiveness of using artificial intelligence (AI) in WDs for forecasting or predicting BG levels.

Methods

We searched 7 of the most popular bibliographic databases. Two reviewers performed study selection and data extraction independently before cross-checking the extracted data. A narrative approach was used to synthesize the data. Quality assessment was performed using an adapted version of the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool.

Results

From the initial 3872 studies, the features from 12 studies were reported after filtering according to our predefined inclusion criteria. The reference standard in all studies overall (n=11, 92%) was classified as low, as all ground truths were easily replicable. Since the data input to AI technology was highly standardized and there was no effect of flow or time frame on the final output, both factors were categorized in a low-risk group (n=11, 92%). It was observed that classical ML approaches were deployed by half of the studies, the most popular being ensemble-boosted trees (random forest). The most common evaluation metric used was Clarke grid error (n=7, 58%), followed by root mean square error (n=5, 42%). The wide usage of photoplethysmogram and near-infrared sensors was observed on wrist-worn devices.

Conclusions

This review has provided the most extensive work to date summarizing WDs that use ML for diabetic-related BG level forecasting or prediction. Although current studies are few, this study suggests that the general quality of the studies was considered high, as revealed by the QUADAS-2 assessment tool. Further validation is needed for commercially available devices, but we envisage that WDs in general have the potential to remove the need for invasive devices completely for glucose monitoring in the not-too-distant future.

Trial Registration

PROSPERO CRD42022303175; https://tinyurl.com/3n9jaayc
Accuracy of Artificial Intelligence–Based Automated Quantitative Coronary Angiography Compared to Intravascular Ultrasound: Retrospective Cohort Study
Authors: Moon In Tae , Kim Sun-Hwa , Chin Jung Yeon , Park Sung Hun , Yoon Chang-Hwan , Youn Tae-Jin , Chae In-Ho , Kang Si-Hyuck
Published: March 2023

Background

An accurate quantitative analysis of coronary artery stenotic lesions is essential to make optimal clinical decisions. Recent advances in computer vision and machine learning technology have enabled the automated analysis of coronary angiography.

Objective

The aim of this paper is to validate the performance of artificial intelligence–based quantitative coronary angiography (AI-QCA) in comparison with that of intravascular ultrasound (IVUS).

Methods

This retrospective study included patients who underwent IVUS-guided coronary intervention at a single tertiary center in Korea. Proximal and distal reference areas, minimal luminal area, percent plaque burden, and lesion length were measured by AI-QCA and human experts using IVUS. First, fully automated QCA analysis was compared with IVUS analysis. Next, we adjusted the proximal and distal margins of AI-QCA to avoid geographic mismatch. Scatter plots, Pearson correlation coefficients, and Bland-Altman were used to analyze the data.

Results

A total of 54 significant lesions were analyzed in 47 patients. The proximal and distal reference areas, as well as the minimal luminal area, showed moderate to strong correlation between the 2 modalities (correlation coefficients of 0.57, 0.80, and 0.52, respectively; P<.001). The correlation was weaker for percent area stenosis and lesion length, although statistically significant (correlation coefficients of 0.29 and 0.33, respectively). AI-QCA tended to measure reference vessel areas smaller and lesion lengths shorter than IVUS did. Systemic proportional bias was not observed in Bland-Altman plots. The biggest cause of bias originated from the geographic mismatch of AI-QCA with IVUS. Discrepancies in the proximal or distal lesion margins were observed between the 2 modalities, which were more frequent at the distal margins. After the adjustment of proximal or distal margins, there was a stronger correlation of proximal and distal reference areas between AI-QCA and IVUS (correlation coefficients of 0.70 and 0.83, respectively).

Conclusions

AI-QCA showed a moderate to strong correlation compared with IVUS in analyzing coronary lesions with significant stenosis. The main discrepancy was in the perception of the distal margins by AI-QCA, and the correction of margins improved the correlation coefficients. We believe that this novel tool could provide confidence to treating physicians and help in making optimal clinical decisions.
Los órganos “autónomos” de evaluación en México ¿autonomía o independencia?
Authors: López Rodríguez Blanca
Published: March 2023

Los sistemas de monitoreo y evaluación (M&E) de programas públicos en los gobiernos locales y central de México operan desde entes centralizados, descentralizados o autónomos. Por ello, el propósito de este estudio es examinar el nivel de autonomía o control gubernamental de los tres órganos constitucionales autónomos (OCA) de evaluación conocidos como Inevap, Evalúa CDMX y Coneval, mediante un análisis descriptivo y una visión multidimensional de la autonomía gerencial, adopción de políticas, estructural, financiera, legal e intervencionista. Derivado del análisis, se concluye que ninguno cumple el nivel máximo, y aunque tienen rasgos de relevancia constitucional, no son reconocidos como OCA. También se discute la falta de rendición de cuentas, evaluaciones de desempeño, participación social, legitimidad y democratización de los procesos de designación de titulares y consejera(o)s de los OCA, la importancia de evaluar los poderes Judicial y Legislativo, otros OCA y municipios, y se compara la autonomía versus independencia de estos sistemas M&E. Finalmente, si la creación de los OCA tiene como objetivo desempeñar funciones altamente especializadas y técnicas como la política de evaluación, que son exclusivas del Estado, la existencia de sistemas M&E dentro de los poderes tradicionales como el Ejecutivo es una contradicción para el sistema constitucional y el diseño institucional de los órganos “autónomos” de evaluación.
Pengaruh Pelayanan Prima pada Front Office dalam Menjaga Loyalitas Tamu Domestik pada Masa Pendemi Covid-19 Di Kaamala Resort, Ubud
Authors: Sumarini Ni Komang , Susanti Luh Eka
Published: March 2023

Pelayanan merupakan tindakan yang dilakukan dengan berinteraksi melalui fisik dengan seseorang atau lebih demi mendapatkan kepuasan pelanggan. Adapun pelayanan prima adalah segala upaya yang dilakukan oleh sebuah perusahaan dalam memberikan pelayanan terbaik kepada tamu atau konsumen untuk menghasilkan sebuah kepuasan dan loyalitas pelanggan atau konsumen itu sendiri. Adapun tujuan dari penelitian ini yaitu untuk mengetahui pengaruh pelayanan prima pada front office dalam menjaga loyalitas tamu domestik pada masa pandemi covid-19 di Kaamala resort, Ubud.Penelitian ini menggunakan pendekatan kuantitatif dengan bantuan program SPSS. Menurut hasil analisis olah data yang dilakukan pelayanan prima front office berpengaruh secara signifikan terhadap loyalitas tamu domestik pada masa pandemi covid-19 di Kaamala resort, Ubud. Meskipun begitu, pelayanan prima yang dilakukan belum begitu optimal dengan adanya tamu yang mengeluhkan lamanya proses check in yang dilakukan. Saran yang penulis dapat berikan yaitu meningkatkan komunikasi, kerja sama team, serta ketelitian dalam mengecek bookingan reservasi yang akan tiba. Sehingga pelayanan prima tersampaikan dengan sangat baik oleh tamu domestik yang mana nantinya akan menghasilkan loyalitas penuh oleh tamu domestik.
 
Service is an action taken by interacting physically with someone or more in order to get customer satisfaction. The excellent service is all the efforts made by a company to supply the best service to guests or consumers to produce a satisfaction and loyalty of customers or consumers themselves. The purpose of this research is to determine the effect of excellent service at the front office in maintaining the loyalty of domestic guests during the covid-19 pandemic at Kaamala resort, Ubud. This study uses a quantitative approach with the help of the SPSS program. According to the results of data processing analysis carried out by excellent front office services, it significantly affected the domestic guests loyalty during the COVID-19 pandemic at Kaamala resort, Ubud. However, the excellent service carried out has not been optimal with guests complaining about the length of the check-in process. The advice that the author can give is to improve communication, teamwork, and accuracy in checking upcoming reservation bookings. Thus, that excellent service is delivered very well by domestic guests which will result in full loyalty by domestic guests.
Kualitas Pelayanan Bellboy di Courtyard by Marriott Bali Nusa Dua Resort
Authors: Warmadewa I Made Prahlada Gusti
Published: March 2023

Penelitian ini yang berjudul “Kualitas Pelayanan Bellboy di Courtyard by Marriott Bali Nusa Dua Resort” yang membahas kualitas pelayanan bellboy berdasarkan 5 variabel “RATER” yaitu responsiveness, assurance, tangible, empathy, & reliability. Penelitian ini bertujuan untuk mengetahui kualitas pelayanan bellboy di Courtyard by Marriott Bali Nusa Dua Resort. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan kuesioner sebagai teknik pengumpulan data dengan analisis uji validitas, uji reliabilitas. Pengumpulan sampel menggunakan sampel Non propability dan jumlah responden dalam penelitian ini yang berjumlah 30 orang tamu yang menginap di hotel yang ditemui secara kebetulan di area hotel Courtyard by Marriott Bali Nusa Dua Resort. Hasil dari penelitian yang didapat yaitu deskripsi data dari masing-masing variabel kualitas pelayanan Bellboy yaitu : tangible (4,36), realibility (4.10), responsive (4,16), empathy (4,34), dan assurance (4,15). Dimana dapat ditarik kesimpulan yaitu kualitas pelayanan Bellboy di Courtyard By Marriot Bali Nusa Dua Resort menunjukan rata-rata baik, dengan 3 variabel kualitas pelayanan menunjukan hasil yang baik dan 2 variabel kualitas pelayanan menunjukan hasil sangat baik.
 
This study, entitled "Quality of Bellboy Service at Courtyard by Marriott Bali Nusa Dua Resort" which discusses the quality of bellboy service based on 5 variables "RATER" , as follows responsiveness, assurance, tangible, empathy, & reliability. The purpose of this research was to determine the quality of service bellboys at Courtyard by Marriott Bali Nusa Dua Resort. This research is a quantitative research and information were collected by a questionnaires with analysis of validity and reliability test. The collection of samples using non-probability samples and the amount of respondents in this study was 30 guests staying at the Courtyard by Marriott Bali Nusa Dua Resort hotel area. The results of the research obtained are descriptions of data from each Bellboy service quality variable, as follows; tangible (4.36), reliability (4.10), responsive (4.16), empathy (4.34), and assurance (4.15 ). Where it can be concluded that the service quality of Bellboy at the Courtyard By Marriot Bali Nusa Dua Resort shows a good average, with 3 service quality variables showing good results and 2 service quality variables showing very good results.
Implementasi Metode Up-Selling di Potato Head Beach Club
Authors: Dinatai Putu Agus Krisna , Sanjiwani Gusti Agung Mirah
Published: March 2023

Implementasi metode up-selling kurang optimal dilakukan oleh pramusaji di Potato Head Beach Club. Hal ini dapat dilihat dari kurangnya tindak lanjut dan pemeliharaan terhadap standar up-selling yang dilakukan oleh pramusaji di Potato Head Beach Club. Tujuan penelitian adalah mengetahui implementasi dan faktor-faktor pramusaji melakukan metode up-selling di Potato Head Beach Club. Penelitian menggunakan pendekatan deskriptif kualitatif dengan metode pengumpulan data dengan cara observasi, wawancara, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa implementasi metode up-selling berdasarkan teori ahli yang diterapkan pada standar operasional prosedur di Potato Head Beach Club sudah dilaksanakan dengan baik seperti: mencari calon pelanggan/pembeli, melakukan pendekatan kepada calon pelanggan/pembeli, presentasi dan demonstrasi, mengatasi keberatan atau penolakan, penutupan. Namun ada satu (1) poin yang belum di lakukan dengan baik, yaitu melakukan tindak lanjut dan pemeliharaan seperti melakukan quality check terhadap makanan yang disajikan. Faktor yang mendukung pramusaji dalam mengimplementasikan up-selling adalah product knowledge, first impression dan pendekatan yang pramusaji dilakukan dan faktor cuaca. Manajemen Potato Head Beach Club diharapkan agar lebih meningkatkan pelatihan tentang product knowledge dan memaksimalkan implementasi up-selling di Potato Head Beach Club, agar tetap sejalan dengan standar yang sudah di tetapkan oleh perusahaan.
 
The implementation of the less than optimal up-selling method was carried out by the waitress at Potato Head Beach Club. This can be seen from the lack of follow-up and maintenance of up-selling standards by the waiters at Potato Head Beach Club. The purpose of the study was to determine the implementation and factors of the waiter doing the up-selling method at Potato Head Beach Club. The study used a qualitative descriptive approach with data collection methods by observation, interviews, and documentation studies. The results show that the implementation of the up-selling method based on expert theory applied to standard operating procedures at Potato Head Beach Club has been carried out well such as: looking for prospective customers/buyers, approaching potential customers/buyers, presentations and demonstrations, overcoming objections or complaints, rejection, and farewell. However, there is one (1) point that has not been done well, namely carrying out follow-up and maintenance such as conducting quality checks on the food served. Factors that support waiters in implementing up-selling are product knowledge, first impressions and the approach that the waiter takes and weather factors. Potato Head Beach Club management is expected to improve training on product knowledge and implementation of up-selling at Potato Head Beach Club, in order to stay in line with the standards set by the company.
Analisis Pengaruh Visibility Credibility Attraction Power Celebrity Endorsment Terhadap Minat Kunjungan Tamu di Hotel Four Points by Sheraton Manado
Authors: Supit Enrico , Sudarmawan I Wayan Eka , Rinayanthi Ni Made
Published: March 2023

Penelitian membahas tentang pengaruh promosi yang dilakukan oleh selebgram Anggia Kloer dalam mempromosikan fasiltas dan event – event yang akan diadakan melalui selebgram dengan maksud meningkatkan kepercayaan konsumen di Manado agar dapat dikenal oleh banyak orang. Tujuan dari penelitian ini untuk mengetahui apakah visibility, credibility, attraction, power berpengaruh positif dan signifikan terhadap minat kunjungan tamu di hotel Four Points by Sheraton Manado. Populasi dalam penelitian ini adalah tamu yang pernah menginap di Four Points By Sheraton Manado, mempunyai instagram dan mengikuti Anggia Kloer di instagram. Sampel Penelitian ini berjumlah 40 orang. Data penelitian ini diperoleh dengan menyebarakan kuesioner secara online menggunakan Google Form kepada responden. Teknik analisis statik yang digunakan adalah regresi linier berganda, uji validitas, uji reliabiltas, uji t, dan uji f. Berdasarkan hasil Visibility, credibility, attraction dan power selebgram secara parsial berpengaruh positif dan signifikan terhadap minat kunjungan di Hotel Four Point by Sheraton Manado. Visibility, credibility, attraction dan power selebgram secara simultan berpengaruh positif dan signifikan terhadap minat kunjungan di Hotel Four Point by Sheraton Manado.
 
The study discusses the influence of promotions carried out by selebgram Anggia Kloer inpromoting facilities and events that will be held through the program with selebgram of increasing consumer confidence in Manado so that it can be known by many people. The purpose of this study was to determine whether visibility, credibility, attraction, power had a positive and significant effect on the interest of visiting guests at the Four Points by Sheraton Manado hotel. The population in this study are guests who have stayed at Four Points by Sheraton Manado, have Instagram and follow Anggia Kloer on Instagram. The sample of this study amounted to 40 people. The research data was obtained by distributing online questionnaires using Google Form to respondents. Static analysis techniques used are multiple linear regression, validity test, reliability test, t test, and f test. Based on the results of Visibility, credibility, attraction and power of the program, partially positive and significant effect on interest in visiting the Four Point Hotel by Sheraton Manado. Visibility, credibility, attraction and power of the program simultaneously have a positive and significant effect on interest in visiting the Four Point Hotel by Sheraton Manado.
Монголын шатах ашигт малтмал, тэдгээрийг агуулсан тунамал савууд
Authors: Б. Эрдэнэцогт
Published: March 2023

During the last decade, significant geological studies on fossil fuels and sedimentary basins in Mongolia have been completed; e.g., more than 100 coal deposits were explored. This review includes recent advances in tectonic setting of sedimentary basins, depositional environments of fossil fuel hosting sedimentary rocks, and quality and resources of coal, oil shale and petroleum source rocks. It also covers the results of coking coal blending studies, oil shale pyrolysis and the outcome of the first evaluation of coal bed methane potential of Mongolia.
EFFECTS OF VARIOUS LIGHT INTENSITIES ON PHYCOCYANIN COMPOSITION OF CYANOBACTERIUM LIMNOSPIRA FUSIFORMIS (VORONICHIN) NOWICKA-KRAWCZYK, MÜHLSTEINOVÁ & HAUER
Authors: kareem Haider , Alghanmi Haider
Published: March 2023

Phycocyanin denotes a photosynthetic pigment discovered in Rhodophyta and cyanobacteria, which has been used in medical, industrial, and agricultural applications. In general, phycocyanin production by cyanobacteria depends on many environmental conditions, mainly light during the cultivation period. The goal of this research was to see how various light intensities of 47, 52, as well as 60 µmol m-2 s-1, affected the Phycocyanin production of cyanobacterium Limnospira fusiformis cultured in Zarrouk medium with a maximum temperature of 28°C. The outcomes revealed that with mild light intensity (52 µmol m-2 s-1), increased phycocyanin production of 11.94 ng/mg took place. With regard to greater light intensity (60 µmol m-2 s-1), the lesser phycocyanin production of 0.57 ng/mg took place. These results give a good impression that moderate lighting increases phycocyanin production, but high light intensity inhibits it. The statistical analysis results also showed that there are significant differences between the light intensities used in the study at a level of p<0.05. Therefore, this study concluded that phycocyanin was affected by light intensity. Light regime optimization gives a good yield of this pigment. In this study, high phycocyanin production by cyanobacterium Limnospira fusiformis occurred in mild light intensity (52 µmol m-2 s-1).
A TWO-WAREHOUSE INVENTORY MODEL WITH REWORK PROCESS AND TIME-VARYING DEMAND
Authors: Nurhasril Nurnadiah , Supadi Dr. Siti Suzlin , Omar Prof. Dr. Mohd
Published: March 2023

A two-warehouse inventory model with deteriorating items and rework process with time varying demand rate is presented. The Last-In-First-Out (LIFO) and First-In-First-Out (FIFO) policies are considered with the assumption that the holding cost is higher in the rented warehouse (RW) compared to the owned warehouse (OW). The aim of the proposed model is to determine the optimum values of time in a production cycle that will minimise the total relevant cost, TRC*. We have utilised Microsoft Excel Solver as a solution tool, in which the generalised reduced gradient (GRG Nonlinear) method has been chosen as the solving method. The result is further verified using the built-in function in the Mathematica software. We observed that given same changes are made to the parameters in both the LIFO and FIFO systems, a lower total relevant cost, TRC* is obtained in the LIFO system. This shall mean that the LIFO system is less expensive than the FIFO system, provided that the holding cost in RW is higher than the holding cost in OW. The flow of inventory in the LIFO system suggests that items stored last in the owned warehouse will be dispatched first. This is an important factor for manufacturers in ensuring that items are distributed at optimal freshness.
TWO-SAMPLE TEST FOR RANDOMLY CENSORED DATA
Authors: Ayushee Ayushee , Kumar Narinder , Goyal Manish
Published: March 2023

In this paper, a nonparametric test has been proposed for the two-sample scale problem, when sample observations are randomly right censored. The proposed test is based on the extremes of observations as an extension of commonly used Gehan’s test for two-sample problem. Critical values are obtained through simulation for various lifetime distributions at different sample sizes. Power performance for the proposed test is studied considering various distributions. On comparing with the Gehan’s test, it is found that the proposed test has more statistical power and efficiency for some special cases. An illustration with real-life data set is also provided.
Comparison of Low-Frequency-Commutation Modulation Techniques in a Symmetrical Cascaded H-Bridge Multilevel Inverter
Authors: Vite Pedro Martín García , Covarrubias Juan H. Almazán , Arredondo Juan M. Ramírez
Published: March 2023

Among the power inverters, modular multilevel converters (MMC) have
gained popularity due to their advantages over conventional two-level
inverters. Although the MMC utilizes more power switches than
traditional inverters, the former exhibits notable benefits such as low
total harmonic distortion, low switching losses with lower voltage
stress, high power quality, reduced electromagnetic interface, and
modularity with numerous degrees of freedom to synthesize output
waveforms. Concerning the synthesized voltage quality, several
low-frequency modulation techniques have been proposed to produce output
voltage with low harmonic content. A particular case of study consisting
of a three-phase even-level MMC inverter is taken as a benchmark to
comparatively evaluate four methods for synthesizing high-quality output
voltage. The employed techniques are ( i) selective harmonic
elimination (SHE), ( ii) generalized SHE, ( iii) THD
Voltage Minimization, and ( iv) Optimum Nearest Level Modulation,
selected based on the phase and line-to-line output voltage THD. The
model is formulated to compute the commutating angles to control the MMC
submodules. Simulations show individual performance under the same
operating conditions. A lab-scale prototype is built to corroborate the
theoretical approach. The results allow the selection of the most
convenient modulation technique based on the number of commutations and
harmonic spectrum.
CDDQNgen: An approach to generate class integration test order Based on Categorical Double DQN algorithm
Authors: Zhang Yanmmei , Li Jianli , Jiang Shujuan , Ding Yanru , Yuan Guan
Published: March 2023

Class integration testing is an essential issue in software integration
testing, and different class integration test order significantly impact
the cost of testing. The Class Integration Test Order (CITO) problem is
to find an optimal order of class integration test order to reduce the
cost of software testing. The existing approaches tend to fall into
local optimality when applied to complex systems and fail to achieve a
better test order. This paper proposes a CITO generation approach based
on deep reinforcement learning Categorical Double DQN (CDDQN) to address
this limitation. The process uses the continuous interaction of the
agent with the environment generated by inter-class dependencies to
learn valuable experience and eventually obtain the optimal class
integration test order. Experiments are conducted in eight systems to
compare with graph-based, search-based, and reinforcement learning-based
approaches. The experimental results show that the approach proposed in
this paper can find CITO with lower stubbing complexity for most
systems.
Use of home pulse oximetry to enhance remote COVID-19 monitoring: Evaluating a single centre experience.
Authors: France Megan , Porter Angus , Bennett Cameron , McCarthy Kate
Published: March 2023

Abstract Introduction Telehealth and remote monitoring of patients of
patients with mild COVID-19 infection have developed rapidly in response
to the pandemic. Many healthcare systems have embraced telehealth for
remote clinical monitoring and pulse oximetry for enhanced monitoring.
Methods The experience of a large healthcare centre’s COVID Virtual Ward
was reviewed retrospectively with a particular focus on evaluating the
effectiveness, safety and utility of finger pulse oximetry within the
home. Data from a 2 month period in early 2022 during a BA1 Omicron wave
was retrospectively reviewed. 551 high risk patients were issued with
pulse oximeters for monitoring oxygen saturations within their home. All
patients received daily clinical review via telephone by a nurse or
doctor. The group was highly vaccinated with only 6.4% of the cohort
unvaccinated. Oximeters were promptly delivered via a courier service
across a vast geographical area. Results Pulse oximetry was well
utilised by most patients. Only 2.7% of the cohort demonstrated resting
oxygen saturations of <94% during their Virtual Ward
admission. Most patients reporting dyspnoea were able to be safely
managed without escalation to an emergency department due to reassuring
clinical and oximetry assessment. Home oxygen saturations correlated
well with saturations recorded within the ED, with no patients found to
have lower saturations compared with home saturations. Discussion Within
a high risk population experiencing COVID-19 infection, pulse oximetry
was a useful tool in clinical assessment and allowed a substantial
reduction in COVID-19 related ED presentations.
The Influence of Aerosol Hygroscopicity on Clouds and Precipitation over Western Ghats, India
Authors: Ray Avishek , Bhowmik Moumita , Hazra Anupam , Pandithurai Govindan
Published: March 2023

We examine the role of aerosol hygroscopicity (κ) affects clouds and
precipitation formation over the Western Ghats (WG) in India using
various numerical model simulations (i.e., particle-by-particle based
small-scale, high resolution mesoscale model). For the diffusional
growth of cloud droplets, the size dependent hygroscopicity is used in
κ- Köhler equation of direct numerical simulation. The results of the
small-scale model reveal that the distribution of cloud drop size varies
from the initial mixing state to well mix state due to variation in κ.
The value of κ is obtained from HTDMA instruments at High Altitude Cloud
Physics Laboratory, India. The idealized and real simulations using WRF
model with aerosol-aware Thompson microphysics scheme are conducted by
changing κ values. Depending on the type of clouds (shallow or deep),
different κ values determine the mass, number and precipitation of cloud
and rain droplets. Low hygroscopicity (organics) simulates more and
smaller drops, as well as uplifts below freezing level, resulting in
more ice phase hydrometeors. Organic aerosols have a significant impact
on the formation of more snow and graupel hydrometeors. As compared to
high κ, low hygroscopicity weakens updrafts at the intermediate level
and strengthens them at the upper level in the deep cloud region. The
intensity of precipitation varies due to low and high κ. The findings
indicate that aerosol composition has a significant impact on the
activation of cloud condensation nuclei. This study suggests that
aerosol hygroscopicity is essential in weather prediction models in
order to integrate aerosol chemical compositions.
Biogas production and greenhouse gas mitigation using fish waste from Bragança/Brazil
Authors: da Silva Dayse Maria Sá , Cavalcanti Jorge , do Nascimento Adalberto , Peres Sérgio , Alves Marileide , Benachour Mohand
Published: March 2023

The potential of biogas production using fish waste (FW) and its effect on
greenhouse gas (GHG) reduction and on energy production were evaluated on
this research. FW was co-digested with anaerobic sewage sludge (SS). The FW
was collected in the city of Bragan?a, northern Brazil, in which the fish
industry is the main activity with a FW production of approximately 9,000
kg?day-1. The experimental part included five SS/FW ratios, and in two
experiments hydrogen was added. The experiments were carried out for 30 days
and the effect on the cumulative biogas and methane yields were analyzed.
The GHG reduction was estimated using the amount of FW not discarded in the
Bragan?a open dump; and the electricity generation was calculated using the
methane yield. Besides, two kinetic models were performed. The results
presented a GHG reduction of 1,619 tons of CO2e and an electricity
production of 372 to 956 MWh?year-1. The analysis of variance indicated that
the methane production was highly dependent on the SS/FW ratios which ranged
from 76 to 138 mL?gvs-1. Finally, this research showed the benefit of using
FW to generate biogas and electricity while reducing GHG emissions in a city
where there is no energy project.
How Does a Convolutional Neural Network Trained to Differentiate between Invasive Melanoma and Melanoma In situ Generalize when Assessing Dysplastic Naevi?
Authors: Gillstedt Martin , Segerholm Klara , Mannius Ludwig , Paoli John , Polesie Sam
Published: March 2023

Abstract is missing (Short communication)
Gingival Conditioning with Provisional Composite Veneer Prior to Final Dental Restoration: Three-year Follow-up
Authors: Mueller B , Rauber GB , Linhares LA , Bernardon JK , Santini E , Pottmaier LF
Published: March 2023

This manuscript reports a three-year follow-up of a case of gingival conditioning with a provisional composite veneer prior to diastema closure and tooth recontouring with direct composites. This conservative treatment resulted in a natural and harmonious smile.
Polychromatic Composite and Resin Infiltration Restorations in the Esthetic Zone: A Five-year Clinical Report
Authors: Karimi K , Fischer NG , Jurado CA , Villalobos-Tinoco J , Tsujimoto A
Published: March 2023

Objective

This case report describes the use of a combination of a polychromatic resin composite restoration and resin infiltration to achieve a satisfactory esthetic outcome that has lasted over five years.

Clinical Considerations

The patient’s primary complaint was a desire to replace an existing stained resin composite on the facial and mesial surfaces of the maxillary left central incisor, and a white spot on the facial surface of the maxillary right central incisor. After clinical evaluation, the patient was offered either replacement of the restoration with a polychromatic restoration simulating a white spot, or a combined treatment with polychromatic composite and resin infiltration restorations, which was recommended. The patient selected the latter treatment. A putty matrix was fabricated, and a quick mock-up was done using various enamel and dentin shades of resin composite to determine proper material selection. The previous resin composite restoration was removed, and layers of new dentin, body, and enamel composite were placed. An interproximal matrix was used in order to provide ideal contour and contact. Finishing and polishing procedures were performed. The maxillary right central incisor was treated with resin infiltration in order to subdue the white spot on the facial surface.

Conclusions

Polychromatic resin composite and resin infiltration restorations to replace a stained restoration and mask a white spot can achieve desired results in the esthetic zone and maintain them for five years.
Effectiveness and Color Stability of Resin Infiltration on Demineralized and Hypomineralized (MIH) Enamel in Children: Six-month Results of a Prospective Trial
Authors: Ozgur B , Unverdi G Erbas , Ertan AA , Cehreli ZC
Published: March 2023

Introduction

To evaluate the masking effect and color stability of resin infiltration treatment in demineralized (white spot lesion) and hypomineralized (molar incisor hypomineralization) enamel lesions of young permanent anterior teeth.

Methods

Eighty-four (84) anterior teeth with molar incisor hypomineralization or white spot lesions were treated with resin infiltration. The CIE L*a*b* values of sound enamel and enamel lesions were assessed with spectrophotometer and digital image analysis at baseline, immediate postop, 1 week and 6 months. The difference in ΔL, Δa, Δb, and ΔE measurements between sound enamel and the enamel lesions was compared using the repeated analysis of variance (ANOVA) test at p < 0.05.

Results

The enamel lesions were clearly discernible from the sound adjacent enamel at baseline. After resin infiltration, there was a significant drop in ΔE values of sound enamel and enamel lesions compared to baseline, and this difference did not change for 6 months, indicating a durable masking effect. At baseline and after 6 months, there was no significant difference in the ΔE values of the test groups.

Conclusion

The demineralized and hypomineralized enamel defects were effectively masked by resin infiltration, which remained clinically stable for 6 months.
Mewaspadai Bencana: Perspektif Global tentang Komunikasi Risiko Bencana
Authors: Suryandari Nikmah , Wijayani Qoni’ah Nur
Published: March 2023

Pertumbuhan penduduk, globalisasi, dan perubahan lingkungan membuat masyarakat lebih rentan terhadap bencana. Untuk mencegah kerugian besar dari nyawa dan harta benda yang mengakibatkan penderitaan manusia, negara-negara di dunia saat ini membutuhkan sistem peringatan dini, yang merupakan bagian integral dari komunikasi risiko bencana. Bencana adalah konsekuensi yang terjadi ketika kondisi alam atau teknologi mempengaruhi masyarakat rentan seperti banjir, angin puting beliung, atau bencana alam lainnya. Kerugian yang menyertai bencana adalah kerugian finansial dan sosialEstimates menunjukkan bahwa bencana alam di seluruh dunia telah menyebabkan kerugian ekonomi lebih dari $ 1, 3 triliun dolar. Makalah ini berupaya untuk meninjau sejumlah kerangka teoritis yang menjelaskan bagaimana masyarakat menanggapi peringatan risiko bencana, serta mengidentifikasi komponen peringatan yang efektif dan teknik evaluatif yang dapat digunakan untuk menilai keberhasilan penerapan sistem peringatan bencana. Tujuan dari tulisan ini adalah untuk mendeskripsikan variabel-variabel yang mempengaruhi peringatan bencana secara umum. Kajian kebencanaan serta konsep dan kajian praktis mengenai berbagai bencana di dunia.
Penerapan Model Case Based Learning (CBL) untuk Mengembangkan Critical Thinking Skills Siswa dalam Pembelajaran Geografi di SMA Negeri 1 Kuta Utara
Authors: Dharmayanthi Ni Putu Irma
Published: March 2023

Penelitian ini bertujuan untuk menganalisis pengimplementasian Model Case Based Learning dalam mengembangkan Critical Thinking Skills siswa pada pembelajaran geografi di SMA N 1 Kuta Utara, menganalisis Critical Thinking Skills siswa setelah model Case Based Learning diimplementasikan dalam pembelajaran Geografi di SMA N 1 Kuta Utara, dan menganalisis dampak model Case Based Learning terhadap Critical Thinking Skills siswa dalam pembelajaran Geografi di SMA N 1 Kuta Utara. Populasi Penelitian ini adalah Siswa kelas XI IPS yang berjumlah 208 orang dan Guru yang mengajar di SMA Negeri 1 Kuta Utara yang berjumlah 2 orang. Penentuan sampel secara Purposive Random Sampling. Penelitian ini menggunakan metode eksperimen. eksperimen yang digunakan dalam penelitian ini adalah quasi experimental (eksperimen semu) dengan desain Non-equivalent Control Group Desain. Hasil Penelitian menemukan bahwa Model Case Base Learning yang diterapkan oleh guru di SMA Negeri 1 Kuta Utara pada kelas XI IPS 2 dalam pembelajaran geografi sudah terkategori baik dengan nilai rata-rata hasil observasi sebesar 79.35 Berdasarkan hasil pengujian Hipotesis terdapat pengaruh yang cukup signifikan penerapan Model Case Base Learning dengan hasil belajar siswa, dimana terjadi peningkatan hasil belajar saat menggunakan Model Case Base Learning. Berdasarkan eksperimen yang telah dilakukan, Model Case Base Learning terbukti berdampak terhadap peningkatan Critical Thinking Skills siswa yang diterapkan model Case Base Learning, dibanding siswa dengan model konvensional.