bluuebunny/crossref_metadata_2025 huggingface dataset:
A Neck-Thyroid Phantom with Small Sizes of Thyroid Remnants for Postsurgical I-123 and I-131 SPECT/CT Imaging
Authors: Michael Konstantinos , Hadjiconstanti Anastasia , Lontos Antonis , Demosthenous George , Frangos Savvas , Parpottas Yiannis
Published: April 2023

Post-surgical I-123 and I-131 SPECT/CT imaging can provide information on the presence and sizes of thyroid remnants and/or metastasis for an accurate re-staging of disease to apply an individualized radioiodine therapy. The purpose of this study was to develop and validate a neck–thyroid phantom with small sizes of thyroid remnants to be utilized for the optimization of post-surgical SPECT/CT imaging. 3D printing and molding techniques were used to develop the hollow human-shaped and -sized phantom which enclosed the trachea, esophagus, cervical spine, clavicle, and multiple detachable sections with different sizes of thyroid remnant in clinically relevant positions. CT images were acquired to evaluate the morphology of the phantom and the sizes of remnants. Triple-energy window scattered and attenuation corrected SPECT images were acquired for this phantom and for a modified RS-542 commercial solid neck–thyroid phantom. The response and sensitivity of the SPECT modality for different administered I-123 and I-131 activities within the equal-size remnants of both phantoms were calculated. When we compared the phantoms, using the same radiopharmaceutical and similar activities, we found that the measured sensitivities were comparable. In all cases, the I-123 counting rate was higher than the I-131 one. This phantom with capabilities to insert different small sizes of remnants and simulate different background-to-remnants activity ratios can be utilized to evaluate postsurgical thyroid SPECT/CT imaging procedures.
Microstructure and Properties of Ti(C,N)-Based Cermets with AlxCoCrFeNiTi Binder
Authors: Liu Meiling , Sun Zhen , Liu Peng , Hai Wanxiu , Chen Yuhong
Published: April 2023

AlxCoCrFeNiTi (x = 0.1, 0.3, 0.6, 1) powders were prepared via mechanical alloying and were used as binders for SPS-produced Ti(C,N)-based cermets. The effects of AlxCoCrFeNiTi binder on phase composition, morphology, room-temperature mechanical properties, and oxidation resistance of cermets were studied. The research showed that cermets with AlxCoCrFeNiTi binders exhibited a more homogeneous core–rim structure than cermets with cobalt binders. The Vickers hardness and fracture toughness of cermets with AlxCoCrFeNiTi binders increased with the aluminum molar ratio due to the grain refinement and solid solution strengthening effect of carbonitrides. After static oxidation at 1000 °C, the mass gain of the cermets with AlxCoCrFeNiTi binders changed according to a quasi-parabolic law, and the lowest mass gain was obtained in the cermet with Al0.6CoCrFeNiTi binder. The oxidation kinetics curve of the benchmark cermet with cobalt followed a linear law. The oxidation product of Ti(C,N)-based cermet with cobalt was rich in TiO2, and the Ti(C,N)-based cermets with AlxCoCrFeNiTi binders were transformed into complex oxides, such as NiMoO4, NiWO4, FeMoO4, Fe3Ti3O9, and Ni3TiO7. The oxide layer on the cermet with Al0.6CoCrFeNiTi appeared to be dense and protective, which inhibited the diffusion of oxygen into the cermet and improved the oxidation resistance of the final product.
Inhibition Effect of Pseudomonas stutzeri on the Corrosion of X70 Pipeline Steel Caused by Sulfate-Reducing Bacteria
Authors: Qiu Lina , Zhao Dandan , Zheng Shujia , Gong Aijun , Liu Zhipeng , Su Yiran , Liu Ziyi
Published: April 2023

Microbiologically influenced corrosion (MIC) is a common phenomenon in water treatment, shipping, construction, marine and other industries. Sulfate-reducing bacteria (SRB) often lead to MIC. In this paper, a strain of Pseudomonas stutzeri (P. stutzeri) with the ability to inhibit SRB corrosion is isolated from the soil through enrichment culture. P. stutzeri is a short, rod-shaped, white and transparent colony with denitrification ability. Our 16SrDNA sequencing results verify the properties of P. stutzeri strains. The growth conditions of P. stutzeri bacteria and SRB are similar, and the optimal culture conditions are about 30 °C, pH 7, and the stable stage is reached in about seven days. The bacteria can coexist in the same growth environment. Using the weight loss method, electrochemical experiments and composition analysis techniques we found that P. stutzeri can inhibit the corrosion of X70 steel by SRB at 20~40 °C, pH 6~8. Furthermore, long-term tests at 3, 6 and 9 months reveal that P. stutzeri can effectively inhibit the corrosion of X70 steel caused by SRB.
Microstructural Aspects of the Fabrication of Al/Al2O3 Composite by Friction Stir Processing
Authors: Malopheyev Sergey S. , Zuiko Ivan S. , Mironov Sergey Yu. , Kaibyshev Rustam O.
Published: April 2023

The purpose of this work was the examination of microstructural evolution during the fabrication of an Al/Al2O3 composite by friction stir processing (FSP). In order to obtain new insight into this process, a longitudinal section of the produced composite was studied, and advanced characterization techniques (including electron backscatter diffraction and microhardness mapping) were applied. It was found that the reinforcing particles rapidly rearranged into the “onion-ring” structure, which was very stable against the subsequent dispersion. Specifically, the remnants of the comparatively coarse-scale particle agglomerations have survived even after 12 FSP passes. Therefore, it was concluded that three or four FSP passes, which are often applied in practice, are not sufficient to provide a homogeneous dispersion of the reinforcing particles. It was also revealed that the gradual distribution of the nanoscale Al2O3 particles throughout the aluminum matrix promoted a subtle reduction in both the portion of high-angle boundaries and the average grain size. These observations were attributed to the particle pinning of grain-boundary migration and dislocation slip.
Sustainable Innovation: Turning Waste into Soil Additives
Authors: Marczak Daria , Lejcuś Krzysztof , Lejcuś Iwona , Misiewicz Jakub
Published: April 2023

In recent years, a dynamic increase in environmental pollution with textile waste has been observed. Natural textile waste has great potential for environmental applications. This work identifies potential ways of sustainably managing natural textile waste, which is problematic waste from sheep farming or the cultivation of fibrous plants. On the basis of textile waste, an innovative technology was developed to support water saving and plant vegetation- biodegradable water-absorbing geocomposites (BioWAGs). The major objective of this study was to determine BioWAG effectiveness under field conditions. The paper analyses the effect of BioWAGs on the increments in fresh and dry matter, the development of the root system, and the relative water content (RWC) of selected grass species. The conducted research confirmed the high efficiency of the developed technology. The BioWAGs increased the fresh mass of grass shoots by 230-420% and the root system by 130-200% compared with the control group. The study proved that BioWAGs are a highly effective technology that supports plant vegetation and saves water. Thanks to the reuse of waste materials, the developed technology is compatible with the assumptions of the circular economy and the goals of sustainable development.
Hydrothermal Reduction of CO2 to Value-Added Products by In Situ Generated Metal Hydrides
Authors: Zeng Xu , Yin Guodong , Zhao Jianfu
Published: April 2023

An integrated process by coupling hydrothermal reactions, including CO2 reduction and H2O dissociation with metals, is proposed. The hydrogen could be rapidly produced under hydrothermal conditions, owing to the special characteristics of high temperature water, generating metal hydrides as intermediates. Hydrogen production from the H2O dissociation under hydrothermal conditions is one of the most ideal processes due to its environmentally friendly impact. Recent experimental and theoretical studies on the hydrothermal reduction of CO2 to value-added products by in situ generated metal hydrides are introduced, including the production of formic acid, methanol, methane, and long-chain hydrocarbons. These results indicate that this process holds promise in respect to the conversion of CO2 to useful chemicals and fuels, and for hydrogen storage, which could help alleviate the problems of climate change and energy shortage.
Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
Authors: Dinter Jonas , Friedrich Ralf P. , Yang Hai , Pilarsky Christian , Mangge Harald , Pöttler Marina , Janko Christina , Alexiou Christoph , Lyer Stefan
Published: April 2023

Pancreatic ductal adenocarcinoma is a hard-to-treat, deadly malignancy. Traditional treatments, such as surgery, radiation and chemotherapy, unfortunately are still not able to significantly improve long-term survival. Three-dimensional (3D) cell cultures might be a platform to study new drug types in a highly reproducible, resource-saving model within a relevant pathophysiological cellular microenvironment. We used a 3D culture of human pancreatic ductal adenocarcinoma cell lines to investigate a potential new treatment approach using superparamagnetic iron oxide nanoparticles (SPIONs) as a drug delivery system for mitoxantrone (MTO), a chemotherapeutic agent. We established a PaCa DD183 cell line and generated PANC-1SMAD4 (−/−) cells by using the CRISPR-Cas9 system, differing in a prognostically relevant mutation in the TGF-β pathway. Afterwards, we formed spheroids using PaCa DD183, PANC-1 and PANC-1SMAD4 (−/−) cells, and analyzed the uptake and cytotoxic effect of free MTO and MTO-loaded SPIONs by microscopy and flow cytometry. MTO and SPION–MTO-induced cell death in all tumor spheroids in a dose-dependent manner. Interestingly, spheroids with a SMAD4 mutation showed an increased uptake of MTO and SPION–MTO, while at the same time being more resistant to the cytotoxic effects of the chemotherapeutic agents. MTO-loaded SPIONs, with their ability for magnetic drug targeting, could be a future approach for treating pancreatic ductal adenocarcinomas.
Mechanical Properties and Microstructure of Austenite—Ferrite Duplex Stainless Steel Hybrid (Laser + GMAW) and SAW Welded Joint
Authors: Krawczyk Ryszard , Słania Jacek , Golański Grzegorz , Pfeifer Tomasz
Published: April 2023

The purpose of the research was to develop a technology for producing thick-walled duplex steel welded joints. The material used in the research was X2CrNiMoN22 duplex steel in the form of a 15 mm thick plate. The welded joint was produced by the modern, high-performance Hybrid Laser Arc Welding (HLAW) method. The HLAW method involves welding a joint using a laser, the Gas Metal Arc Welding (GMAW) method and the Submerged Arc Welding (SAW) method. The HLAW method was used to make the root pass of the double butt welded joint, while the filler passes were made by the SAW method. The obtained welded joint was subjected to non-destructive and destructive testing. The non-destructive and macroscopic tests allowed the joint to be classified to the quality level B. Microscopic examinations revealed the presence of ferritic–austenitic microstructure in the base material and the weld, with different ferrite content in specific joint areas. The analysed joint had high strength properties (tensile strength (TS) ~ 790 ± 7 MPa) and high ductility of weld metal (~160 ± 4 J) heat-affected zone (~216 ± 26 J), and plasticity (bending angle of 180° with no macrocracks). At the same time, hardness on the cross-section of the welded joint did not exceed 280 HV10.
A Fast Prediction Model for Liquid Metal Transfer Modes during the Wire Arc Additive Manufacturing Process
Authors: Ouyang Jiaqi , Li Mingjian , Lian Yanping , Peng Siyi , Liu Changmeng
Published: April 2023

The liquid metal transfer mode in wire arc additive manufacturing (WAAM), plays an important role in determining the build quality. In this study, a fast prediction model based on the Young–Laplace equation, momentum equation, and energy conservation, is proposed, to identify the metal transfer modes, including droplet, liquid bridge, and wire stubbing, for a given combination of process parameters. To close the proposed model, high-fidelity numerical simulations are applied, to obtain the necessary inputs required by the former. The proposed model’s accuracy and effectiveness are validated by using experimental data and high-fidelity simulation results. It is proved that the model can effectively predict the transition from liquid bridge, to droplet and wire stubbing modes. In addition, its errors in dripping frequency and liquid bridge height range from 6% to 18%. Moreover, the process parameter windows about transitions of liquid transfer modes have been established based on the model, considering wire feed speed, travel speed, heat source power, and material parameters. The proposed model is expected to serve as a powerful tool for the guidance of process parameter optimization, to achieve high-quality builds.
Study on Flexural Performance of Aluminum Alloy Gusset Joints Subjected to Bending Moment and Shear Force
Authors: Wang Hao , Li Jialiang , Li Pengcheng , Zhong Li , Zhang Xiaoyue , Li Chao
Published: April 2023

Aluminum alloy gusset (AAG) joints are widely applied in space reticulated shell structures. To investigate the flexural performance of AAG joints under the combined action of shear force and in-plane and out-of-plane bending moments, this analysis was developed by means of finite element (FE) models implemented in the non-linear code ABAQUS, and the accuracy of the FE simulation results based on the existing AAG joint test results was verified. The FE simulation results effectively described the mechanical properties of the AAG joints, including the failure mode, deformation process and bending moment-rotation curves. Furthermore, a parametric study was conducted by varying the height of the member section, the number of bolts, the radius of the joint plate, the thickness of the joint plate, the bolt preload force, and the ratio of in-plane to out-of-plane bending moments. It was found that these parameters had different effects on the bending behavior of the AAG joints.
Efficient Synthesis of 2D Mica Nanosheets by Solvothermal and Microwave-Assisted Techniques for CO2 Capture Applications
Authors: Weerasinghe P. Vishakha T. , Wu Shunnian , Lee W. P. Cathie , Lin Ming , Anariba Franklin , Li Xu , Seng Debbie Hwee Leng , Sim Jia Yu , Wu Ping
Published: April 2023

Mica, a commonly occurring mineral, has significant potential for various applications due to its unique structure and properties. However, due to its non-Van Der Waals bonded structure, it is difficult to exfoliate mica into ultrathin nanosheets. In this work, we report a rapid solvothermal microwave synthesis of 2D mica with short reaction time and energy conservation. The resulting exfoliated 2D mica nanosheets (eMica nanosheets) were characterized by various techniques, and their ability to capture CO2 was tested by thermogravimetric analysis (TGA). Our results showed an 87% increase in CO2 adsorption capacity with eMica nanosheets compared to conventional mica. Further characterization by Fourier-transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS), as well as first-principles calculations, showed that the high specific surface area and deposited K2CO3 layer contribute to the increased CO2 adsorption on the mica nanosheets. These results speak to the potential of high-quality eMica nanosheets and efficient synthesis processes to open new avenues for new physical properties of 2D materials and the development of CO2 capture technologies.
A Lightweight AlCrTiV0.5Cux High-Entropy Alloy with Excellent Corrosion Resistance
Authors: Peng Zhen , Li Baowei , Luo Zaibin , Chen Xuefei , Tang Yao , Yang Guannan , Gong Pan
Published: April 2023

Lightweight high-entropy alloys (HEAs) are a new class of low-density, high strength-to-weight ratio metallic structural material. Understanding their corrosion behavior is crucial for designing microstructures for their practical applications. This work investigates the electrochemical corrosion behavior of lightweight HEAs AlCrTiV0.5Cux (x = 0, 0.2, 0.4, 0.6, 0.8, and 1.0) in a 0.6 M NaCl solution. These HEAs were produced by vacuum arc melting. In contrast to 304L stainless steel, all of the alloys exhibited lower current density levels caused by self-corrosion, with AlCrTiV0.5 demonstrating the highest corrosion resistance (0.131 μA/cm2). Corrosion resistance decreased along with the content of copper because copper segregation accelerated local corrosion throughout the alloy.
Hydration Heat Control of Mass Concrete by Pipe Cooling Method and On-Site Monitoring-Based Influence Analysis of Temperature for a Steel Box Arch Bridge Construction
Authors: Zhang Tan , Wang Hua , Luo Yuejing , Yuan Ye , Wang Wensheng
Published: April 2023

The steel box arch bridge in this study will be subjected to various temperature effects from the construction to the operation stage, including the cement hydration heat effect and the sunshine temperature effect caused by an ambient temperature change. Therefore, it is very important to control the temperature effect of steel box arch bridges. In this study, the newly built Dafeng River Bridge is selected as the steel box arch bridge. This study aims to investigate the temperature effect including hydration heat and the sunshine temperature effect of the construction process of a rigid frame-tied steel box arch bridge. The manuscript presents that the heat dissipation performance of concrete decreases with the increase in the thickness of a mass concrete structure. The average maximum temperature values of layer No. 3 are about 1.3, 1.2, and 1.1 times the average maximum temperature value of layer No. 1 for the mass concrete of the cushion cap, main pier and arch abutment, respectively. The higher the molding temperature is, the higher the maximum temperature by the hydration heat effect is. With each 5 °C increase in the molding temperature, the maximum temperature at the core area increases by about 4~5 °C for the mass concrete. The pipe cooling method is conducive to the hydration heat control effect of mass concrete. Based on the monitored temperature change and displacement change, the influences of daily temperature change on the steel lattice beam and arch rib are analyzed. A temperature rise will cause the structure to have a certain camber in the longitudinal direction, and the longitudinal or transverse displacement caused by the sunshine temperature change is no less than the vertical displacement. Due to the symmetrical construction on both sides of the river, the arch rib deformation on both sides presents symmetrical synchronous changes. Based on 84 h of continuous temperature monitoring on-site, the changing trends of the arch back temperature and ambient temperature are consistent and their difference is small during 1:00~4:00 in the morning, which is determined as the appropriate closure time for the newly built Dafeng River Bridge.
The Quadratic Constitutive Model Based on Partial Derivative and Taylor Series of Ti6242s Alloy and Predictability Analysis
Authors: Zhang Jiansheng , Xiao Guiqian , Deng Guoyong , Zhang Yancheng , Zhou Jie
Published: April 2023

To solve the problem of insufficient predictability in the classical models for the Ti6242s alloy, a new constitutive model was proposed, based on the partial derivatives from experimental data and the Taylor series. Firstly, hot compression experiments on the Ti6242s alloy at different temperatures and different strain rates were carried out, and the Arrhenius model and Hensel–Spittel model were constructed. Secondly, the partial derivatives of logarithmic stress with respect to temperature and logarithmic strain rate at low, medium and high strain levels were analyzed. Thirdly, two new constitutive models with first- and second-order approximation were proposed to meet the requirements of high precision. In this new model, by analyzing the high-order differential data of experimental data and combining the Taylor series theory, the minimum number of terms that can accurately approximate the experimental rheological data was found, thereby achieving an accurate prediction of flow stress with minimal material parameters. In the new model, by analyzing the high-order differential of the experimental data and combining the theory of the Taylor series, the minimum number of terms that can accurately approximate the experimental rheological data was found, thereby achieving an accurate prediction of flow stress with minimal material parameters. Finally, the prediction accuracies for the classical model and the new model were compared, and the predictabilities for the classical models and the new model were proved by mathematical means. The results show that the prediction accuracies of the Arrhenius model and the Hensel–Spittel model are low in the single-phase region and high in the two-phase region. In addition, second-order approximation is required between the logarithmic stress and logarithmic strain rate, and first-order approximation is required between logarithmic stress and temperature to establish a high-precision model. The order of prediction accuracy of the four models from high to low is the quadratic model, Arrhenius model, linear model and HS model. The prediction accuracy of the quadratic model in all temperatures and strain rates had no significant difference, and was higher than the other models. The quadratic model can greatly improve prediction accuracy without significantly increasing the material parameters.
Effect of Furfurylation on Bamboo-Scrimber Composites
Authors: Li Wanju , Xie Guijun , Ma Hongxia , Li Xingwei
Published: April 2023

Bamboo is a material with excellent development prospects. It is increasingly used in furniture, decoration, building, and bridge construction. In this study, Furfurylated bamboo bundles and phenol-formaldehyde resin were used to make bamboo-scrimber composites (BSCs) via molding-recombination and hot-pressing processes. The effects of the impregnation mode, furfuryl-alcohol concentration, and curing temperature on the various physical–mechanical properties and durability of the composites were evaluated. Scanning-electron microscopy (SEM) was used to observe the microstructural differences. Fourier-transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) were employed to investigate changes in the chemical constituents. The heat resistance was also investigated using thermogravimetric analysis. The results showed that the density of the furfurylated BSC increased by up to 22% compared with that of the BSC-C with the same paving mode. The furfurylated BSCs had lower moisture contents: the average moisture content of the furfurylated BSCs was 25~50% lower than that of the BSC-C. In addition, the furfurylated BSCs showed better dimensional stability and durability, since the decay-resistance grade of the BSCs was raised from decay resistance (class II) to strong decay resistance (class I). In terms of the mechanical properties, the furfurylation had a slight negative effect on the mechanical strength of the BSCs, and the modulus of rupture (MOR) and horizontal shear strength (HSS) of the BSCs were increased to a certain extent under most of the treatment conditions. In particular, the highest HSS for indoor use and MOR of the furfurylated BSCs increased by 21% and 9% compared with those of the untreated BSCs, respectively. The SEM results indicated that the FA resin effectively filled in the bamboo-cell cavities and vessels, and the modified bamboo-parenchyma cells were compressed more tightly and evenly. The FTIR and XPS spectroscopy showed that the hydroxyl group of carboxylic acid of the bamboo-cell-wall component reacted with that of the furan ring, and the cellulose and hemicellulose underwent acid hydrolysis to a certain extent after the furfurylation. Overall, the present study highlights the potential of furfurylation as a modification method to enhance BSC products. Further research should focus on improving the ability of furfurylated BSCs to prevent the growth of Botryodiplodia theobromae. Additionally, the influence of furfuryl-alcohol resin on the bonding strengths of PF adhesives should be further clarified.
The Importance of Solvent Effects in Calculations of NMR Coupling Constants at the Doubles Corrected Higher Random-Phase Approximation
Authors: Jessen Louise Møller , Reinholdt Peter , Kongsted Jacob , Sauer Stephan P. A.
Published: April 2023

In this work, 242 NMR spin–spin coupling constants (SSCC) in 20 molecules are calculated, either with correlated wave function methods, SOPPA and HRPA(D), or with density functional theory based on the B3LYP, BHandH, or PBE0 functionals. The calculations were carried out with and without treatment of solvation via a polarizable continuum model in both the geometry optimization step and/or the SSCC calculation, and thereby, four series of calculations were considered (the full-vacuum calculation, the full-solvent calculation, and the two cross combinations). The results were compared with experimental results measured in a solvent. With the goal of reproducing experimental values, we find that the performance of the PBE0 and BHandH SSCCs improves upon including solvation effects. On the other hand, the quality of the B3LYP SSCCs worsens with the inclusion of solvation. Solvation had almost no effect on the performance of the SOPPA and HRPA(D) calculations. We find that the PBE0-based calculations of the spin–spin coupling constants have the best agreement with the experimental data.
Subclasses of p-Valent Functions Associated with Linear q-Differential Borel Operator
Authors: Cătaş Adriana , Borşa Emilia-Rodica , El-Deeb Sheza M.
Published: April 2023

The aim of the present paper is to introduce and study some new subclasses of p-valent functions by making use of a linear q-differential Borel operator.We also deduce some properties, such as inclusion relationships of the newly introduced classes and the integral operator Jμ,p.
Levy Flight-Based Improved Grey Wolf Optimization: A Solution for Various Engineering Problems
Authors: Bhatt Bhargav , Sharma Himanshu , Arora Krishan , Joshi Gyanendra Prasad , Shrestha Bhanu
Published: April 2023

Optimization is a broad field for researchers to develop new algorithms for solving various types of problems. There are various popular techniques being worked on for improvement. Grey wolf optimization (GWO) is one such algorithm because it is efficient, simple to use, and easy to implement. However, GWO has several drawbacks as it is stuck in local optima, has a low convergence rate, and has poor exploration. Several attempts have been made recently to overcome these drawbacks. This paper discusses some strategies that can be applied to GWO to overcome its drawbacks. This article proposes a novel algorithm to enhance the convergence rate, which was poor in GWO, and it is also compared with the other optimization algorithms. GWO also has the limitation of becoming stuck in local optima when used in complex functions or in a large search space, so these issues are further addressed. The most remarkable factor is that GWO purely depends on the initialization constraints such as population size and wolf initial positions. This study demonstrates the improved position of the wolf by applying strategies with the same population size. As a result, this novel algorithm has enhanced its exploration capability compared to other algorithms presented, and statistical results are also presented to demonstrate its superiority.
On Mathematical and Logical Realism and Contingency
Authors: Tadić Jovan M.
Published: April 2023

This study presents the claim that mathematics and logic are merely highly formalized reflections, grounded in the physical laws of conservation. The claim generally correlates with John Stuart Mill’s known stance, but unlike his general view, it specifies which elements of the natural kingdom are reflected by mathematical objects and statements. As the study claims one version of physicalism, it raises the question of the necessity vs. contingency of mathematics and concludes that the necessity of mathematical judgments depends on the necessity of the conservation laws themselves. Since the conservation laws are only certain, it follows that there is no basis to claim the necessity of mathematical statements themselves, and that it is only possible to speak of a conditional necessity in the sense that mathematics is necessarily such as it is only in a world governed by conservation laws. Such conditional necessity does not possess the being of absolute necessity. Mathematics can only be considered necessary to the extent that the reflected world described by it is necessary, which further implies the claim that mathematics is necessarily a posteriori and synthetic. The entire series of mathematical proof types, including the most commonly utilized reduction ad absurdum, ultimately derives its strength from experience.
Analysis of the Characteristics and Speed of Spread of the “FUNA” on Twitter
Authors: Moreno Sebastián , Bórquez-Paredes Danilo , Martínez Valentina
Published: April 2023

The funa is a prevalent concept in Chile that aims to expose a person’s bad behavior, punish the aggressor publicly, and warn the community about it. Despite its massive use on the social networks of Chilean society, the real dissemination of funas among communities is unknown. In this paper, we extract, generate, analyze, and compare the Twitter social network’s spread of three tweets related to “funas” against three other trending topics, through the analysis of global network characteristics over time (degree distribution, clustering coefficient, hop plot, and betweenness centrality). As observed, funas have a specific behavior, and they disseminate as quickly as a common tweet or more quickly; however, they spread thanks to several network users, generating a cohesive group.
Extension of Divisible-Load Theory from Scheduling Fine-Grained to Coarse-Grained Divisible Workloads on Networked Computing Systems
Authors: Wang Xiaoli , Veeravalli Bharadwaj , Wu Kangjian , Song Xiaobo
Published: April 2023

The big data explosion has sparked a strong demand for high-performance data processing. Meanwhile, the rapid development of networked computing systems, coupled with the growth of Divisible-Load Theory (DLT) as an innovative technology with competent scheduling strategies, provides a practical way of conducting parallel processing with big data. Existing studies in the area of DLT usually consider the scheduling problem with regard to fine-grained divisible workloads. However, numerous big data loads nowadays can only be abstracted as coarse-grained workloads, such as large-scale image classification, context-dependent emotional analysis and so on. In view of this, this paper extends DLT from fine-grained to coarse-grained divisible loads by establishing a new multi-installment scheduling model. With this model, a subtle heuristic algorithm was proposed to find a feasible load partitioning scheme that minimizes the makespan of the entire workload. Simulation results show that the proposed algorithm is superior to the up-to-date multi-installment scheduling strategy in terms of achieving a shorter makespan of workloads when dealing with coarse-grained divisible loads.
Genesis Analysis of Special Deformation Characteristics for Super-High Arch Dams in the Alpine and Gorge Regions of Southwest China
Authors: Shao Chenfei , Zhao Erfeng , Xu Yanxin , Zheng Sen , Tian Shiguang
Published: April 2023

During the operational period, unexpected upstream deformation has been observed in several super-high arch dams located in the alpine and gorge regions. In addition, the phenomenon of the downstream dam deformation monitoring values being apparently smaller than the numerical simulation results appears in some super-high arch dams. This paper focuses on the genetic mechanism of a super-high arch dam’s special deformation characteristics. The finite element method (FEM) was used to analyze the effects of solar radiation, valley contraction, and overhanging on super-high arch dam’s deformation behavior. First, the influences of solar radiation on the temperature field and deformation characteristics of the super-high arch dam under the shading effects of the mountain and the dam body were investigated. Second, the impacts of valley contraction on the deformation characteristics of the super-high arch dam during the storage period were studied. Subsequently, the impact of the overhanging effect on the super-high arch dam’s deformation was explored. Finally, a case study was conducted on the basis of the Jinping I super-high arch dam to evaluate the effectiveness of the proposed analytical method. It is indicated that the dam’s special deformation can be explained reasonably. Above all, in order to accurately analyze and predict the deformation characteristics of super high-arch dams in the alpine and gorge regions of Southwest China, solar radiation, valley contraction, and the dam-overhanging effect need to be considered as influencing factors of dam deformation.
Bioinformatics Prediction and Experimental Verification Identify CAB39L as a Diagnostic and Prognostic Biomarker of Kidney Renal Clear Cell Carcinoma
Authors: Wu Yunfei , Xu Zhijie , Chen Xiaoyi , Fu Guanghou , Tian Junjie , Shi Yue , Sun Junjie , Jin Baiye
Published: April 2023

Background and Objectives: Calcium-binding protein 39-like (CAB39L) has been reported to be downregulated and possessed diagnostic and prognostic values in several types of cancer. However, the clinical value and mechanism of CAB39L in kidney renal clear cell carcinoma (KIRC) remain unclear. Materials and Methods: Bioinformatics analysis was conducted using different databases including TCGA, UALCAN, GEPIA, LinkedOmics, STRING, and TIMER. One-way variance analysis and t-test were chosen to investigate the statistical differences of CAB39L expression in KIRC tissues with different clinical characteristics. The receiver operating characteristic (ROC) curve was chosen to assess the discriminatory capacity of CAB39L. Kaplan–Meier curves were employed for assessing the influence of CAB39L on the progression-free survival (PFS), disease-specific survival (DSS), and overall survival (OS) of KIRC patients. The independent prognostic significance of clinical parameters for OS such as CAB39L expression in KIRC patients was estimated by Cox analysis. A series of in vitro functional experiments and Western blot (WB) and immunohistochemistry (IHC) were used to validate the relative protein expression and function of CAB39L. Results: The mRNA and protein levels of CAB39L were relatively downregulated in KIRC samples. Meanwhile, hypermethylation of the CAB39L promoter region was possibly associated with its low expression in KIRC. The ROC curve showed that the mRNA expression of CAB39L had a strong diagnostic value for both early and late KIRC. Kaplan–Meier survival curves indicated that a higher mRNA level of CAB39L predicted good PFS, DSS, and OS. The mRNA expression of CAB39L was an independent prognostic factor (hazard ratio = 0.6, p = 0.034) identified by multivariate Cox regression analysis. The Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) analysis exhibited that CAB39L was mainly associated with substance and energy metabolism. Finally, overexpression of CAB39L impaired the proliferation and metastasis of KIRC cells in vitro. Conclusions: CAB39L possesses prognostic and diagnostic capacity in KIRC.
Impact of Preemptive Postoperative Pressure Support Ventilation and Physiotherapy on Postoperative Pulmonary Complications after Major Cervicofacial Cancer Surgery: A before and after Study
Authors: Salama Guillaume , Motamed Cyrus , Elmawieh Jamie , Suria Stéphanie
Published: April 2023

Introduction: Complex cervicofacial cancer surgery with free flap reconstruction is known to have a high incidence of postoperative pulmonary complications (PPCs). We hypothesized that by implementing an optimized respiratory protocol, including preemptive postoperative pressure support ventilation, physiotherapy, and critical respiratory support and follow-up, we could decrease the incidence of PPCs. Patients and methods: We evaluated the incidence of PPCs over two periods in two groups of patients having a routine or optimized postoperative respiratory protocol: 156 adult patients undergoing major cervicofacial cancer surgery were assessed; 91 were in Group 1 (routine) and 65 were in Group 2 (optimized). In Group 1, no ventilatory support sessions were performed. The incidence of pulmonary complications in both groups was compared using a multivariate analysis. Mortality was also compared until one year postoperatively. Results: In Group 2 with an optimized protocol, the mean number of ventilatory support sessions was 3.7 ± 1 (minimum 2, maximum 6). The incidence of respiratory complications, which was 34% in Group 1 (routine), was reduced by 59% OR = 0.41 (0.16; 0.95), p = 0.043) to 21% for the optimized Group 2. No difference in mortality was found. Conclusions: The present retrospective study showed that using an optimized preemptive respiratory pressure support ventilation combined with physiotherapy after a major cervicofacial surgery could possibly help reduce the incidence of pulmonary complications. Prospective studies are needed to verify these findings.
Influence of Humidity and Heating Rate on the Continuous ZIF Coating during Hydrothermal Growth
Authors: Choi Eunji , Lee Choong-Hoo , Kim Dae Woo
Published: April 2023

Zeolitic imidazolate frameworks (ZIFs) have potential for various gas and ion separations due to their well-defined pore structure and relatively easy fabrication process compared to other metal–organic frameworks and zeolites. As a result, many reports have focused on preparing polycrystalline and continuous ZIF layers on porous supports with good separation performance in various target gases, such as hydrogen extraction and propane/propylene separation. To utilize the separation properties in industry, membrane is required to be prepared in large scale with high reproducibility. In this study, we investigated how humidity and chamber temperature influence the structure of a ZIF-8 layer prepared by the hydrothermal method. Many synthesis conditions can affect the morphology of polycrystalline ZIF membranes, and previous studies have mainly focused on reaction solutions, such as precursor molar ratio, concentration, temperature, and growth time. On the other hand, we found that the humidity of the chamber and the heating rate of the solution also lead to dramatic changes in the morphology of ZIF membranes. To analyze the trend between humidity and chamber temperature, we set up the chamber temperature (ranging from 50 °C to 70 °C) and relative humidity (ranging from 20% to 100%) using a thermo-hygrostat chamber. We found that as the chamber temperature increased, ZIF-8 preferentially grew into particles rather than forming a continuous polycrystalline layer. By measuring the temperature of the reacting solution based on chamber humidity, we discovered that the heating rate of the reacting solution varied with humidity, even at the same chamber temperature. At a higher humidity, the thermal energy transfer was accelerated as the water vapor delivered more energy to the reacting solution. Therefore, a continuous ZIF-8 layer could be formed more easily at low humidity ranges (ranging from 20% to 40%), while micron ZIF-8 particles were synthesized at a high heating rate. Similarly, under higher temperatures (above 50 °C), the thermal energy transfer was increased, leading to sporadic crystal growth. The observed results were obtained with a controlled molar ratio, in which zinc nitrate hexahydrate and 2-MIM were dissolved in DI water at a molar ratio of 1:45. While the results are limited to these specific growth conditions, our study suggests that controlling the heating rate of the reaction solution is critical for preparing a continuous and large-area ZIF-8 layer, particularly for the future scale-up of ZIF-8 membranes. Additionally, humidity is an important factor in forming the ZIF-8 layer, as the heating rate of the reaction solution can vary even at the same chamber temperature. Further research related to humidity will be necessary for the development of large-area ZIF-8 membranes.
Additive Manufacturing of Aluminum Alloys for Aeronautic Applications: Advantages and Problems
Authors: Montanari Roberto , Palombi Alessandra , Richetta Maria , Varone Alessandra
Published: April 2023

In aeronautics, additive manufacturing (AM) leads to specific benefits, mainly connected to topological optimization for weight reduction, the decrease in “buy-to-fly” ratio, and the operations of maintenance, repair, and overhaul. Al alloys processed by AM technologies are extensively investigated and play an increasing role in the production of aircraft structural parts. Based on the recent literature and research activity of the authors, this work examines advantages and drawbacks involved in the printing of Al alloys. Defects, microstructure, mechanical properties, development of new alloys, and postprocess treatments are described and critically discussed by focusing the attention on the effects of the specific alloy composition, AM process, and process parameters.
Effect of CaO/Al2O3 Ratio on Physical Properties of Lime-Alumina-Based Mould Powders
Authors: Seyrek Mustafa , Thackray Richard
Published: April 2023

High-aluminium steels contain a significant amount of aluminium. The reaction between Al in the liquid steel and SiO2 in lime-silica-based mould powders during the continuous casting process of high Al steel causes chemical compositional changes in the mould powders, subsequently affecting the surface quality of slabs. In order to solve the aforementioned problem, lime-alumina-based mould powders have been developed, which can lead to an increase in the surface quality of cast slabs by inhibiting steel/slag interaction. However, the mould slag tends to crystallise easily, which leads to a deterioration of the mould lubrication. In view of this aspect, it is important to develop and optimize lime-alumina-based mould powders to meet the requirements of continuous casting of high-aluminium steels. In this study, the changes in crystallinity, viscosity and melting temperature of lime-alumina-based mould powders with the effects of increasing the CaO/Al2O3 ratio have been observed through STA (Simultaneous Thermal Analysis), HSM (Hot Stage Microscopy), XRD (X-ray Diffraction), IPT (Inclined Plate Test) and rotational viscometer. The crystallisation behaviour of these mould powders was evaluated by generating CCT (continuous cooling transformation) diagrams. Additionally, the changes in steel chemistry have also been analysed using XRF (X-ray fluorescence) and ICP (Inductively Coupled Plasma Mass Spectrometer). The results of these analyses demonstrated that crystallinity of lime-alumina-based mould powder is increased while the initial crystallisation temperature and viscosity are decreased by CaO/Al2O3 additions. However, the degree of steel/slag interaction decreases with an increase in Al2O3 content.
A Study on the Dynamic Evolution Mechanism of the Steady Magnetic Field on the Internal Flow Behavior of a Laser Melting Pool
Authors: Xie Songjing , Jiang Ke , Wang Liang , Yao Jianhua
Published: April 2023

A 2D model of laser melting consisting of heat transfer, hydrodynamic flow, surface tension, and a free surface motion was established. A physical field simulation of the laser melting process was performed, and the effect of steady magnetic field parameters on the internal flow and temperature fields of the melt pool was analyzed and validated by experiments. The results show that the steady magnetic field can suppress the melt pool flow rate, but slightly influences its temperature field, and with an increase in the magnetic field strength, the ripples on the melting surface decrease with increasing magnetic flux density. Compared with the molten pool depth experiment results, the simulation molten pool depth was 792 μm, representing a difference in value of 13.5%. The surface ripples of the molten pool fluctuated greatly in the absence of a magnetic field, while the surface ripples were suppressed when the magnetic flux density was 2T. This is consistent with the simulation results, thus effectively demonstrating the simulation model’s accuracy.
Utilization of Renewable Carbon in Electric Arc Furnace-Based Steel Production: Comparative Evaluation of Properties of Conventional and Non-Conventional Carbon-Bearing Sources
Authors: Kieush Lina , Schenk Johannes , Koveria Andrii , Rantitsch Gerd , Hrubiak Andrii , Hopfinger Horst
Published: April 2023

Conventional (anthracite, calcined petroleum coke, and coke) and non-conventional (biochar, and biocokes (3 wt.% torrefied wood, and 3 wt.% petroleum coke + 3 wt.% charcoal)) carbon-bearing sources have been studied for their use in electric arc furnace (EAF)-based steel production. Commonly, for the use of carbon sources in EAFs, one of the important properties is the content of fixed carbon, the release of volatiles as well as the elemental composition of inorganics. The properties of six carbon sources were analyzed by determining the proximate analysis, X-ray fluorescence analysis (XRF), coke reactivity index (CRI), and strength after reaction with CO2 (CSR), Brunauer–Emmett–Teller (BET) specific surface area and Barrett–Joyner–Halenda (BJH) pore size and volume analysis, ash chemical analysis, optical and scanning microscopy, Raman spectroscopy and X-ray diffraction (XRD) analysis. The results indicate biocoke as a promising option to replace conventional carbon-bearing sources. In the sample set, the fixed carbon, volatiles, and ash content of the biocokes were similar despite the total difference in additives. Additionally, the use of additives did not significantly affect the biocoke reactivity indices, but slightly decreased the strength after the reaction with CO2. Carbon-bearing sources have been characterized in terms of their structural properties. XRD analysis revealed that the amount of disordered carbon increased in the order: coke < calcined petroleum coke ~ biocoke (3 wt.% torrefied wood) < biocoke (3 wt.% petroleum coke + 3 wt.% charcoal) < biochar. The results obtained on the physical, chemical, and structural properties of carbon sources are the basis for further research on the behavior of slag foaming.
High-Fat-Diet Suppressed Ketone Body Utilization for Lipogenic Pathway in Brown Adipose Tissues
Authors: Yamasaki Masahiro , Hasegawa Shinya , Ozaki Shotaro , Imai Masahiko , Saito Daisuke , Takahashi Noriko
Published: April 2023

Brown adipose tissue (BAT) consumes excess lipids and produces lipid metabolites as ketone bodies. These ketone bodies are then recycled for lipogenesis by the enzyme acetoacetyl-CoA synthetase (AACS). Previously, we found that a high-fat diet (HFD) upregulated AACS expression in white adipose tissue. In this study, we investigated the effects of diet-induced obesity on AACS in BAT. When 4-week-old ddY mice were fed a HFD or high-sucrose diet (HSD) for 12 weeks, a significant decrease in Aacs, acetyl-CoA carboxylase-1 (Acc-1), and fatty acid synthase (Fas) expression was observed in the BAT of the HFD group, whereas expression was not affected in the HSD group. In vitro analysis showed decreased Aacs and Fas expression in rat primary-cultured brown adipocytes following isoproterenol treatment for 24 h. In addition, the suppression of Aacs by siRNA markedly decreased the expression of Fas and Acc-1 but did not affect the expression of uncoupling protein-1 (UCP-1) or other factors. These results suggested that HFD may suppress ketone body utilization for lipogenesis in BAT and that AACS gene expression may be important for regulating lipogenesis in BAT. Therefore, the AACS-mediated ketone body utilization pathway may regulate lipogenesis under conditions of excess dietary fat.