bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemental Figure 6 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: April 2023

Effect of knocking down ODC expression in HCT116 colon cancer cells. Colon cancer cells were stably transfected with shMock or shODC. Confirmation of (A, upper left panel) knockdown of ODC protein expression by Western blot; (A, upper right panel) knockdown of ODC transcription level by RT-PCR; and (A, lower panel) knockdown of ODC activity measured as release of L-[1-C14] ornithine. (B) The effect of knocking down ODC expression on anchorage-independent HCT116 colon cancer cell growth. Colonies were counted using a microscope and the Image-Pro PLUS (v6) computer software program. (C) The effect of knocking down ODC expression on HCT116 colon cancer cell growth was analyzed over 1, 2 or 3 days using the MTS assay. (D) The effect of knocking down ODC expression on AP-1 reporter activity was measured using substrates in the reporter assay system. For A-D, data are represented as mean values {plus minus} S.D. of triplicate experiments and the asterisk (*) indicates a significant difference (p < 0.05) versus shMock cells. (E) Effect of knocking down ODC expression on the phosphorylation of ERK1/2 and RSK was determined by Western blotting. Similar results were observed from two independent experiments and representative blots are shown.
Supplementary Figure S6 from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: April 2023

Evaluation of the knockdown efficiency of PAI-1 in HUVECs transfected with siRNA against PAI-1
Supplemental Figure 2 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: April 2023

Effect of herbacetin on activity of various kinases. Herbacetin has no effect on (A) CHK1, (B) EGFR, (C) GSK3beta, (D) JNK1, (E) JNK2, (F) ERK1, (G) ERK2, (H) MEK1, (I) AKT1, (J) AKT2, (K) RSK2, (L) p38 or (M) PI3-K kinase activity or on (N) AdoMetDC activity. The effect of herbacetin on kinase or enzyme activity was determined by using an in vitro kinase or enzyme assay. All data are represented as mean values {plus minus} S.D. of values from duplicates experiments.
Supplementary Table S1 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: April 2023

Association of MALAT1 expression with clinical parameters in RCC patients.
Supplementary table 5 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: April 2023

Microarray and qPCR data showing no induction of PEMT mRNA levels by estrogen in MCF7 and T47D cells
Supplementary Methods from Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest
Authors: Schaaf Lea , Schwab Matthias , Ulmer Christoph , Heine Simon , Mürdter Thomas E. , Schmid Jens O. , Sauer Georg , Aulitzky Walter E. , van der Kuip Heiko
Published: April 2023

More detailed information on materials and methods
Supplementary Dataset S1 from Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines
Authors: Bakdash Ghaith , Buschow Sonja I. , Gorris Mark A.J. , Halilovic Altuna , Hato Stanleyson V. , Sköld Annette E. , Schreibelt Gerty , Sittig Simone P. , Torensma Ruurd , Duiveman-de Boer Tjitske , Schröder Christoph , Smits Evelien L. , Figdor Carl G. , de Vries I. Jolanda M.
Published: April 2023

The detailed composition of all gene sets used in GSEA.
Supplementary Figures S1-S5 from Treatment of Invasive Brain Tumors Using a Chain-like Nanoparticle
Authors: Peiris Pubudu M. , Abramowski Aaron , Mcginnity James , Doolittle Elizabeth , Toy Randall , Gopalakrishnan Ramamurthy , Shah Shruti , Bauer Lisa , Ghaghada Ketan B. , Hoimes Christopher , Brady-Kalnay Susann M. , Basilion James P. , Griswold Mark A. , Karathanasis Efstathios
Published: April 2023

Supplementary Fig. S1. Representative in vivo and ex vivo images using a Maestro FLEX In Vivo Imaging System. Supplementary Fig. S2. Effect of the RF field on the temperature of brain tissues. Supplementary Fig. S3. Bright field microscopy and fluorescence was performed on an entire histological section of the brain stained with Hematoxylin-Eosin (green: CNS-1 glioma cells (GFP)). The same histological section shown in Fig. 4A was used (left panel). Higher magnification of the same section shows the H&E stain of an invasive site (right panel). Supplementary Fig. S4. Cytotoxicity of nanochain particles on CNS-1 cells. Supplementary Fig. S5. Weight progression of animals bearing orthotopic (A) CNS-1 or (B) 9L glioma tumors after DOX treatments.
Supplemental Table 1 from G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program
Authors: Yim Christina Y. , Sekula David J. , Hever-Jardine Mary P. , Liu Xi , Warzecha Joshua M. , Tam Janice , Freemantle Sarah J. , Dmitrovsky Ethan , Spinella Michael J.
Published: April 2023

Genes with altered expression in G0S2 null MEFs as compared to wild-type MEFs
Supplementary Table 1 from Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte–Endothelial Recognition to Foster Tumor Immune Escape
Authors: Corey Daniel M. , Rinkevich Yuval , Weissman Irving L.
Published: April 2023

Normalized Gene Expression Values from FACS-isolated Lin- FSC low, CD144+ CD31+ clones.
Supplementary Figure 1 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: April 2023

Supplementary Figure 1: Expression of p53 target genes is impaired following cisplatin treatment in HNSCC harboring mutant TP53.
Supplementary table 1 from S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase
Authors: Rizza Salvatore , Montagna Costanza , Cardaci Simone , Maiani Emiliano , Di Giacomo Giuseppina , Sanchez-Quiles Virginia , Blagoev Blagoy , Rasola Andrea , De Zio Daniela , Stamler Jonathan S. , Cecconi Francesco , Filomeni Giuseppe
Published: April 2023

WB densitometry and statistical analyses
Supplementary figures legends from S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase
Authors: Rizza Salvatore , Montagna Costanza , Cardaci Simone , Maiani Emiliano , Di Giacomo Giuseppina , Sanchez-Quiles Virginia , Blagoev Blagoy , Rasola Andrea , De Zio Daniela , Stamler Jonathan S. , Cecconi Francesco , Filomeni Giuseppe
Published: April 2023

Supplementary figures legends
Figure S1 from S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase
Authors: Rizza Salvatore , Montagna Costanza , Cardaci Simone , Maiani Emiliano , Di Giacomo Giuseppina , Sanchez-Quiles Virginia , Blagoev Blagoy , Rasola Andrea , De Zio Daniela , Stamler Jonathan S. , Cecconi Francesco , Filomeni Giuseppe
Published: April 2023

Characterization of mitochondrial physiology in GSNOR-downregulating systems.
Supplemental Figure Legends from Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway Activation
Authors: D'Armiento Jeanine , Shiomi Takayuki , Marks Sarah , Geraghty Patrick , Sankarasharma Devipriya , Chada Kiran
Published: April 2023

Legend for Supplemental Figures S1-S2.
Supplementary Table and Supplementary Figures 1 through 6 from Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer
Authors: Lastwika Kristin J. , Wilson Willie , Li Qing Kay , Norris Jeffrey , Xu Haiying , Ghazarian Sharon R. , Kitagawa Hiroshi , Kawabata Shigeru , Taube Janis M. , Yao Sheng , Liu Linda N. , Gills Joell J. , Dennis Phillip A.
Published: April 2023

Supplemental Table 1. Clinical and pathologic characteristics of patients included in tissue microarrays Supplementary Figure 1. B7-H4 expression is low in human and mouse lung cancer cell lines in vitro Supplementary Figure 2. B7-H1 expression does not change with MAPK or proliferation inhibition Supplementary Figure 3. Scoring of PD-L1 and pS6 staining in lung adenocarcinoma and squamous cell carcinoma TMAs Supplementary Figure 4. Co-expression of pS6 and PD-L1 staining in TMAs Supplemental Figure 5. The combination of rapamycin and anti-PD-1 antibody decreases KRAS-driven lung tumor growth Supplementary Figure 6. The combination of rapamycin and αPD-1 blockade decreases NNK-derived syngeneic lung tumor growth.
Supplementary Table and Figure Legends from Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer
Authors: Lastwika Kristin J. , Wilson Willie , Li Qing Kay , Norris Jeffrey , Xu Haiying , Ghazarian Sharon R. , Kitagawa Hiroshi , Kawabata Shigeru , Taube Janis M. , Yao Sheng , Liu Linda N. , Gills Joell J. , Dennis Phillip A.
Published: April 2023

Supplementary Table and Figure Legends
Supplemental Figure S1 from Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast Cancer by Inhibiting Integrin Signaling Axis
Authors: Ranjan Alok , Gupta Parul , Srivastava Sanjay K.
Published: April 2023

Suppression of integrins by penfluridol treatment.
Supplementary table 1 from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: April 2023

Supplementary Table S1. List of antibody clones used for flow cytometry analysis.
Supplementary figures from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: April 2023

Supplementary Figure S1. IL-17-producing cells in C57BL/6 WT mice 7 days after ETBF colonization. Supplementary Figure S2. CD3+ cell recovery from distal colon of WT (CD4Stat3+/+), and CD4Stat3-/- C57BL/6 mice one week after ETBF colonization. Supplementary Figure S3. pStat3 scores in immune cells (IC) and colon epithelial cells do not differ between C57BL/6-CD4Stat3-/- and C57BL/6-CD4Stat3+/+ 3 and 7 days after ETBF colonization . Supplementary Figure S4. Gene expression analysis in distal colon tissue collected from WT (CD4Stat3+/+) (, CD4Stat3-/- and γδ-- - CD4Stat3-/- C57BL/6 mice 7 days after ETBF colonization. Supplementary Figure S5. Difference in IL-17 expression by CD4+ T cells (Th17), γδ+ T cells (γδ T17) and non Th17, non γδT17 cells in the distal colon of WT (CD4Stat3+/+) C57BL/6 mice 7 days after ETBF colonization. Supplementary Figure S6. Macroscopic tumor size distribution in 3 month-ETBF colonized parental Min (Min-CD4Stat3+/+) versus Min-CD4Stat3-/- mice. Supplementary Figure S7. Parental (CD4Stat3+/+) and CD4Stat3-/- Min mice were treated with anti-IL17 mAb between week 6 and 12 following ETBF colonization. Supplementary Figure S8. Myeloid cells accumulation (CD11b+) in colon tumors compared to whole distal colons (tumor and normal tissues) of 3 month ETBF-colonized Min mice. Supplementary Figure S9. Innate lymphoid cells (ILC) reconstitute the lamina propria of BM chimera mice.
Supplementary figure legends from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: April 2023

Legends of figures S1 to S9
Supplementary Figure S1 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

Isogenic HCT116 Cell Lines Show Differential Sensitivity to KRAS Silencing.
Supplementary Figure legends from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Supplementary Figure legends
CAN-15-1348R-Supplementary Figure legends from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Supplementary Figure legends
Supplementary Methods from Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach
Authors: Benzekry Sebastien , Tracz Amanda , Mastri Michalis , Corbelli Ryan , Barbolosi Dominique , Ebos John M.L.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary Materials and Methods from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary Figures S1-S11 from Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach
Authors: Benzekry Sebastien , Tracz Amanda , Mastri Michalis , Corbelli Ryan , Barbolosi Dominique , Ebos John M.L.
Published: April 2023

In vitro fit and direct statistical analysis of the xenograft breast data (S1); Population fit of the tumor growth data that were measured by BL, under the Gomp-Exp model and initial volume Vi fixed by the conversion rule inferred from the correlation between volume and BL (S2); Population fits of the breast xenograft data under different growth theories (S3); Population fits of the kidney isograft data under different growth theories (S4); Second kidney data set used for fitting the data (S5); Individual fits of primary tumor and metastatic burden kinetics Breast animal model (S6); Individual fits of primary tumor and metastatic burden kinetics. Kidney animal model (S7); Link between experimental and model survival (S8); Surgery benefit on survival and metastatic burden reduction as a function of resection size, for varying values of metastatic potential (S9); Population fits of the ortho-surgical metastasis animal models for a dissemination coefficient d(Vp) = ??Vyp and various values of y (S10); Population fits of the ortho-surgical metastasis animal models for various values of the signal-to-cell ratio V0 (S11).
Supplementary Materials and Methods and Supplementary Figure Legends from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
Authors: Adams Brian D. , Wali Vikram B. , Cheng Christopher J. , Inukai Sachi , Booth Carmen J. , Agarwal Seema , Rimm David L. , Győrffy Balázs , Santarpia Libero , Pusztai Lajos , Saltzman W. Mark , Slack Frank J.
Published: April 2023

Supplementary Materials and Methods and Supplementary Figure Legends
Fig.S8 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: April 2023

Characterization of CXCR3 overexpression in MIA PaCa-2 cells in vitro
Supplementary Figure 2 from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
Authors: Adams Brian D. , Wali Vikram B. , Cheng Christopher J. , Inukai Sachi , Booth Carmen J. , Agarwal Seema , Rimm David L. , Győrffy Balázs , Santarpia Libero , Pusztai Lajos , Saltzman W. Mark , Slack Frank J.
Published: April 2023

Figure S2, Related to Figure 2. A-F, Functional characterization of miR-34a re-introduction in additional TNBC and non-TNBC cell lines by way of Matrigel-invasion (A), soft agar growth (B), and BrdU labeling (C) experiments. For BrdU assays, we observed only a 5-10% accumulation of BrdU-positive cells 4 days post-transfection. SA-β-gal assays on MDA-MB-157 (D), and BT-20 (E, left panel) TNBC cells, as compared to MCF-7 luminal-A cells (E, right panel). F, MCF-7 cells stably transfected with either a miR-34a (miR-34a SP) or a control (Empty SP) reporter/sponge construct was assayed for SA-β-gal activity. Two independent miR-34a SP pools were generated. G, Luciferase reporter assays indicative of miR-34a activity in all TNBC, luminal, and normal cell lines used in this study. H, miRNA levels in MDA-MB-231, MDA-MB-436, and BT-549 TNBC cells or BT-474 and MCF-7 Luminal-A cells 72 hours after 10nM miR-34a or miR-Scr transfection. In TNBC cells miR-34a expressing lines harbored lower levels of miR-17/92 family members as compared to miR-Scr treated lines. * Indicates p<0.05, as compared to control conditions.
Fig.S3 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: April 2023

Cocultures of Panc-1 cells with myofibroblasts and expression analysis
Supplementary Table S3 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Genes specifically induced by wild-type ELF4 in T3M-1 Cl-10 cells
Supplementary Table S1 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Caspase activities in T3M-1 Cl-10 cells infected with recombinant retroviruses for the indicated proteins.
Supplementary Figure S9 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

ELF4 mutants do not act in a dominant-negative manner.
Supplementary Movie 4 from Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells
Authors: Cheng Chun-Ting , Kuo Ching-Ying , Ouyang Ching , Li Chien-Feng , Chung Yiyin , Chan David C. , Kung Hsing-Jien , Ann David K.
Published: April 2023

Movie 4. Time-lapse imaging of MDA-MB-231/shKAP1/S473D-KAP1 cells in glucose-depleted medium.
Supplementary Figure S6 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Suppression of ELF4 does not affect cell growth
Supplementary Table S5 from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: April 2023

Enrichment for common genes of HBXIP and c-Myc.
Supplementary method figure from STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment
Authors: Koyama Shohei , Akbay Esra A. , Li Yvonne Y. , Aref Amir R. , Skoulidis Ferdinandos , Herter-Sprie Grit S. , Buczkowski Kevin A. , Liu Yan , Awad Mark M. , Denning Warren L. , Diao Lixia , Wang Jing , Parra-Cuentas Edwin R. , Wistuba Ignacio I. , Soucheray Margaret , Thai Tran , Asahina Hajime , Kitajima Shunsuke , Altabef Abigail , Cavanaugh Jillian D. , Rhee Kevin , Gao Peng , Zhang Haikuo , Fecci Peter E. , Shimamura Takeshi , Hellmann Matthew D. , Heymach John V. , Hodi F. Stephen , Freeman Gordon J. , Barbie David A. , Dranoff Glenn , Hammerman Peter S. , Wong Kwok-Kin
Published: April 2023

This file contains flow cytometry gating strategy used for the analysis of mouse tumors and surface markers for the immune cells described in the manuscript.
Table T1 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Authors: Hubert Christopher G. , Rivera Maricruz , Spangler Lisa C. , Wu Qiulian , Mack Stephen C. , Prager Briana C. , Couce Marta , McLendon Roger E. , Sloan Andrew E. , Rich Jeremy N.
Published: April 2023

Comparison of the glioblastoma organoid growth format with tumorsphere culture and with mouse intracranial xenograft models.
Supplementary Figure S11 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Schematic representation for the dual action of AIMP2 via Smurf2 in TGF-β signal pathway.
Supplementary Figure S4 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

RKIP knockdown in U937 does not affect NF-κB.
Supplementary Figure S3 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

RKIP expression is decreased in AML specimens with a myelomonocytic and monocytic phenotype in AML cohort III (TCGA).
Supplementary Figure S2 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

Myelomonocytic and monocytic AML phenotypes are enriched in AML with RKIP loss.
Supplementary Figure Legend from Nucleolin Promotes Heat Shock–Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis
Authors: Morfoisse Florent , Tatin Florence , Hantelys Fransky , Adoue Aurelien , Helfer Anne-Catherine , Cassant-Sourdy Stephanie , Pujol Françoise , Gomez-Brouchet Anne , Ligat Laetitia , Lopez Frederic , Pyronnet Stephane , Courty Jose , Guillermet-Guibert Julie , Marzi Stefano , Schneider Robert J. , Prats Anne-Catherine , Garmy-Susini Barbara H.
Published: April 2023

Supplementary figure legend
Figure S4 from Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Authors: Timosenko Elina , Ghadbane Hemza , Silk Jonathan D. , Shepherd Dawn , Gileadi Uzi , Howson Lauren J. , Laynes Robert , Zhao Qi , Strausberg Robert L. , Olsen Lars R. , Taylor Stephen , Buffa Francesca M. , Boyd Richard , Cerundolo Vincenzo
Published: April 2023

Characterization of autophagy levels in tumor cell lines cultured under tryptophan deprivation conditions.
Figure S2 from Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Authors: Timosenko Elina , Ghadbane Hemza , Silk Jonathan D. , Shepherd Dawn , Gileadi Uzi , Howson Lauren J. , Laynes Robert , Zhao Qi , Strausberg Robert L. , Olsen Lars R. , Taylor Stephen , Buffa Francesca M. , Boyd Richard , Cerundolo Vincenzo
Published: April 2023

Generation and characterization of SLC1A5 knockdown and LAT1 knockout tumor cell lines.
supplemental figure legend from The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Latorre Elisa , Carelli Stephana , Raimondi Ivan , D'Agostino Vito , Castiglioni Ilaria , Zucal Chiara , Moro Giacomina , Luciani Andrea , Ghilardi Giorgio , Monti Eleonora , Inga Alberto , Di Giulio Anna Maria , Gorio Alfredo , Provenzani Alessandro
Published: April 2023

legends for supplemental figures
Supplemental Figure Legends from Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression
Authors: Marsh Timothy , Wong Irene , Sceneay Jaclyn , Barakat Amey , Qin Yuanbo , Sjödin Andreas , Alspach Elise , Nilsson Björn , Stewart Sheila A. , McAllister Sandra S.
Published: April 2023

Legends for supplemental figures 1-7
supplemental figure 3 from The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Latorre Elisa , Carelli Stephana , Raimondi Ivan , D'Agostino Vito , Castiglioni Ilaria , Zucal Chiara , Moro Giacomina , Luciani Andrea , Ghilardi Giorgio , Monti Eleonora , Inga Alberto , Di Giulio Anna Maria , Gorio Alfredo , Provenzani Alessandro
Published: April 2023

Cell migration/adhesion assays on HuR KD cells and quality controls on the their xenotransplants.
supplemental figure 2 from The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial–Mesenchymal Transition in Breast Cancer
Authors: Latorre Elisa , Carelli Stephana , Raimondi Ivan , D'Agostino Vito , Castiglioni Ilaria , Zucal Chiara , Moro Giacomina , Luciani Andrea , Ghilardi Giorgio , Monti Eleonora , Inga Alberto , Di Giulio Anna Maria , Gorio Alfredo , Provenzani Alessandro
Published: April 2023

HuR expression ablation does not induce anoikis.
Supplementary Table S1 from Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation
Authors: Yu Zu-Yin , Xiao He , Wang Li-Mei , Shen Xing , Jing Yu , Wang Lin , Sun Wen-Feng , Zhang Yan-Feng , Cui Yu , Shan Ya-Jun , Zhou Wen-Bing , Xing Shuang , Xiong Guo-Lin , Liu Xiao-Lan , Dong Bo , Feng Jian-Nan , Wang Li-Sheng , Luo Qing-Liang , Zhao Qin-Shi , Cong Yu-Wen
Published: April 2023

Hematopathologic characteristics of analyzed experimental mice.
Figure S4 from Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Dawkins Joshua B.N. , Wang Jun , Maniati Eleni , Heward James A. , Koniali Lola , Kocher Hemant M. , Martin Sarah A. , Chelala Claude , Balkwill Frances R. , Fitzgibbon Jude , Grose Richard P.
Published: April 2023

Changes in RPKM expression for selected genes identified by RNA-seq, and global levels of H3K4 methylation, following depletion of KMT2D or KMT2C by siRNA.
Supplementary Materials and Methods from Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones
Authors: Ren Yi A. , Mullany Lisa K. , Liu Zhilin , Herron Alan J. , Wong Kwong-Kwok , Richards JoAnne S.
Published: April 2023

Description of additional methods and procedures used in the study.
supplemental tables and figures from Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma
Authors: Lu Yonghai , Li Ning , Gao Liang , Xu Yong-Jiang , Huang Chong , Yu Kangkang , Ling Qingxia , Cheng Qi , Chen Shengsen , Zhu Mengqi , Fang Jinling , Chen Mingquan , Ong Choon Nam
Published: April 2023

Tables S1. Clinical characteristics of subjects in Post-hoc analysis; Tables S2. Clinical characteristics of subjects in validation set; Tables S3. Reproducibility evaluation of LC-MS and GC-MS; Tables S4. 36 metabolites identified by LC-MS; Tables S5. Pearson's correlation analysis in Discovery set; Tables S6. Pearson's correlation analysis in Post-hoc analysis; Tables S7. Acetylcarnitine values in validation set; Figure S1. PCA scores plots of QC samples; Figure S2. Pathological images of HCC tissues; Figure S3. OPLS-DA scores plots of liver tissues; Figure S4. Heat map of 62 identified differential metabolites; Figure S5. Major differential metabolites and pathways in HCC tumors.
Supplementary Table S4 from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells
Authors: Peitzsch Claudia , Cojoc Monica , Hein Linda , Kurth Ina , Mäbert Katrin , Trautmann Franziska , Klink Barbara , Schröck Evelin , Wirth Manfred P. , Krause Mechthild , Stakhovsky Eduard A. , Telegeev Gennady D. , Novotny Vladimir , Toma Marieta , Muders Michael , Baretton Gustavo B. , Frame Fiona M. , Maitland Norman J. , Baumann Michael , Dubrovska Anna
Published: April 2023

Regulation of the genes involved in WNT signaling pathway in the ALDH+ population of DU145 parental (P) cells versus ALDH- population of DU145 P cells.
Supplementary Figure 5 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Fig. 5: Cell cycle profile analysis of P21d-treated MDA-MB231 cells.
Supplementary Figure 4 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Fig. 4: PTK6-dependent regulation of Snail is independent of known Snail regulators.
Supplementary Figure 3 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Fig. 3: Levels of auto-phosphorylated active PTK6 in non-transformed MCF-10A cells and MDA-MB231 cells.
Supplementary Figure S5 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

MvDN30 causes MET shedding under the experimental conditions employed in this study
Supplementary Figure S4 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

Rebound S phase entry mainly relies on MET
Supplementary Figure 1 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Fig. 1: Validation of PTK6 antibody used in immunohistochemistry.
Supplementary Figure 3. Individual participant meta-analysis of diabetes (yes versus no) and liver cancer risk in the Liver Cancer Pooling Project from Body Mass Index, Waist Circumference, Diabetes, and Risk of Liver Cancer for U.S. Adults
Authors: Campbell Peter T. , Newton Christina C. , Freedman Neal D. , Koshiol Jill , Alavanja Michael C. , Beane Freeman Laura E. , Buring Julie E. , Chan Andrew T. , Chong Dawn Q. , Datta Mridul , Gaudet Mia M. , Gaziano J. Michael , Giovannucci Edward L. , Graubard Barry I. , Hollenbeck Albert R. , King Lindsey , Lee I.-Min , Linet Martha S. , Palmer Julie R. , Petrick Jessica L. , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Rosenberg Lynn , Sahasrabuddhe Vikrant V. , Schairer Catherine , Sesso Howard D. , Sigurdson Alice J. , Stevens Victoria L. , Wactawski-Wende Jean , Zeleniuch-Jacquotte Anne , Renehan Andrew G. , McGlynn Katherine A.
Published: April 2023

Results from individual participant meta-analysis of diabetes. Multivariable models include age, sex, study, alcohol, smoking, race and body mass index.
Supplementary Figure 5 from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

Levels of inhibin B
Figure legends to Figs 1 2 and 3 from Body Mass Index, Waist Circumference, Diabetes, and Risk of Liver Cancer for U.S. Adults
Authors: Campbell Peter T. , Newton Christina C. , Freedman Neal D. , Koshiol Jill , Alavanja Michael C. , Beane Freeman Laura E. , Buring Julie E. , Chan Andrew T. , Chong Dawn Q. , Datta Mridul , Gaudet Mia M. , Gaziano J. Michael , Giovannucci Edward L. , Graubard Barry I. , Hollenbeck Albert R. , King Lindsey , Lee I.-Min , Linet Martha S. , Palmer Julie R. , Petrick Jessica L. , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Rosenberg Lynn , Sahasrabuddhe Vikrant V. , Schairer Catherine , Sesso Howard D. , Sigurdson Alice J. , Stevens Victoria L. , Wactawski-Wende Jean , Zeleniuch-Jacquotte Anne , Renehan Andrew G. , McGlynn Katherine A.
Published: April 2023

figure legends for supp. figures 1, 2, and 3
Supplementary Figure 3 from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

FOXO1 and PTEN expression patterns in developing ovaries.
Nwani et al, Supplementary figure legends from Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts
Authors: Nwani Nkechiyere G. , Deguiz Maria L. , Jimenez Benilde , Vinokour Elena , Dubrovskyi Oleksii , Ugolkov Andrey , Mazar Andrew P. , Volpert Olga V.
Published: April 2023

Legends for supplementary figures
Supplementary Tables S1-S4 from Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients
Authors: Bianco Mimma , Gasparri Anna Maria , Colombo Barbara , Curnis Flavio , Girlanda Stefania , Ponzoni Maurilio , Bertilaccio Maria Teresa Sabrina , Calcinotto Arianna , Sacchi Angelina , Ferrero Elisabetta , Ferrarini Marina , Chesi Marta , Bergsagel P. Leif , Bellone Matteo , Tonon Giovanni , Ciceri Fabio , Marcatti Magda , Caligaris-Cappio Federico , Corti Angelo
Published: April 2023

Demographic and clinical data regarding the study population (S1); ELISAs used for the characterization of CgA and its fragments in MM plasma samples (S2); Correlation between BM plasma levels of different CgA analytes and clinical variables in MM patients at diagnosis (S3); Correlation between BM plasma levels of different CgA analytes and FGF2 or VEGF in MM patients at diagnosis (S4).
Supplementary Figures S1-S5 from Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients
Authors: Bianco Mimma , Gasparri Anna Maria , Colombo Barbara , Curnis Flavio , Girlanda Stefania , Ponzoni Maurilio , Bertilaccio Maria Teresa Sabrina , Calcinotto Arianna , Sacchi Angelina , Ferrero Elisabetta , Ferrarini Marina , Chesi Marta , Bergsagel P. Leif , Bellone Matteo , Tonon Giovanni , Ciceri Fabio , Marcatti Magda , Caligaris-Cappio Federico , Corti Angelo
Published: April 2023

Characterization of the new α-373 antibody and *373-ELISA (S1); Levels of different CgA-related analytes in peripheral-blood and bone marrow plasma samples obtained from normal subjects and MM patients stratified according to renal failure and treatment with proton pump inhibitors (S2); BM plasma levels of different CgA forms in MM patients at diagnosis in different disease stages (S3); MM and endothelial cells produce the urinary-type plasminogen activator (S4); Alignment of CgA sequence from different species (S5).
Table S3 from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

List of all putative functional variants in ID8
Supplementary Figure Legends from Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth
Authors: Beauvais DeannaLee M. , Jung Oisun , Yang Yang , Sanderson Ralph D. , Rapraeger Alan C.
Published: April 2023

Legends for supplemental figures
Supplementary figures 12 - 14 from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

Figures S12-S14: Flow cytometry - Ly6C:Ly6G; Flow cytometry - F4:80;iNOS;CD206; Flow cytometry - gating strategy
Supplementary Figure 1 from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

Figure S1: Sanger sequencing data for Trp53 exon 5 in the 4 Trp53-/- ID8 clones
Supplementary data from LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker
Authors: Bressy Christian , Lac Sophie , Nigri Jérémy , Leca Julie , Roques Julie , Lavaut Marie-Nöelle , Secq Véronique , Guillaumond Fabienne , Bui Thi-Thien , Pietrasz Daniel , Granjeaud Samuel , Bachet Jean-Baptiste , Ouaissi Mehdi , Iovanna Juan , Vasseur Sophie , Tomasini Richard
Published: April 2023

Supplementary methods and Figure legends
Figure S4 from LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker
Authors: Bressy Christian , Lac Sophie , Nigri Jérémy , Leca Julie , Roques Julie , Lavaut Marie-Nöelle , Secq Véronique , Guillaumond Fabienne , Bui Thi-Thien , Pietrasz Daniel , Granjeaud Samuel , Bachet Jean-Baptiste , Ouaissi Mehdi , Iovanna Juan , Vasseur Sophie , Tomasini Richard
Published: April 2023

We analyzed the impact of LIF (A) or conditioned media (B) on sNF96.2 cell survival using caspase-3 positive cell measurement.
Table S3 from Mathematical Modeling Reveals That Changes to Local Cell Density Dynamically Modulate Baseline Variations in Cell Growth and Drug Response
Authors: Greene James M. , Levy Doron , Herrada Sylvia P. , Gottesman Michael M. , Lavi Orit
Published: April 2023

Proliferation percentage of cells seeded in different combinations of local and global cell density conditions for 3 days
Figure S3 from LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker
Authors: Bressy Christian , Lac Sophie , Nigri Jérémy , Leca Julie , Roques Julie , Lavaut Marie-Nöelle , Secq Véronique , Guillaumond Fabienne , Bui Thi-Thien , Pietrasz Daniel , Granjeaud Samuel , Bachet Jean-Baptiste , Ouaissi Mehdi , Iovanna Juan , Vasseur Sophie , Tomasini Richard
Published: April 2023

Amalysis of Akt/Stat3 signaling induction following LIF stimulation. We measured the induction of STAT3 (A) and Akt (B) phosphorylation by western blot in sNF96.2 after incubation with LIF recombinant protein. We confirmed the specificity of induction triggered by LIF using LIFR blocking antibody or AG490 inhibitor.
Supplementary Material from Mathematical Modeling Reveals That Changes to Local Cell Density Dynamically Modulate Baseline Variations in Cell Growth and Drug Response
Authors: Greene James M. , Levy Doron , Herrada Sylvia P. , Gottesman Michael M. , Lavi Orit
Published: April 2023

Detailed information on the mathematical model, parameter estimation, and additional experimental protocols
Movie S1 from Mathematical Modeling Reveals That Changes to Local Cell Density Dynamically Modulate Baseline Variations in Cell Growth and Drug Response
Authors: Greene James M. , Levy Doron , Herrada Sylvia P. , Gottesman Michael M. , Lavi Orit
Published: April 2023

24-hr growth dynamics simulation of the circular seeding configuration
Supplementary Table 2 from Inactivation of Cancer-Associated-Fibroblasts Disrupts Oncogenic Signaling in Pancreatic Cancer Cells and Promotes Its Regression
Authors: Dauer Patricia , Zhao Xianda , Gupta Vineet K. , Sharma Nikita , Kesh Kousik , Gnamlin Prisca , Dudeja Vikas , Vickers Selwyn M. , Banerjee Sulagna , Saluja Ashok
Published: April 2023

RNA seq reads
Supplementary Figure S4 from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Supplementary Fig. S4 FAT10 stabilizes eEF1A1 protein levels by attenuating eEF1A1 ubiquitination and degradation in cancer cells.
Supplementary Figure 1-7 from KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis
Authors: Yan Yongmin , LI Zhiwei , Kong Xiangyu , Jia Zhiliang , Zuo Xiangsheng , Gagea Mihai , Huang Suyun , Wei Daoyan , Xie Keping
Published: April 2023

Supplementary Figure 1-7 Figure S1. Effects of KLF4 overexpression on tumorsphere formation and liver metastasis of cancer stem-like cells; Figure S2. Effect of Klf4 gene disruption on cell morphology of mouse pancreatic cancer cells; Figure S3. IHC staining of Klf4 and CD44 expressions in intestinal tissues Figure S4. KLF4 and CD44 expressions in PANC-1 cells; Figure S5. KLF4 inhibits CD44v and ESRP-1 expressions in pancreatic and colon cancer cells; Figure S6. KLF4 expression correlates with metastatic potential in human cancer cells; Figure S7. KLF4/CD44 expressions in primary and metastatic tumor tissues
Supplementary Materials and Methods, Supplementary Tables 1 through 3 from Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells
Authors: Jang Hyun-Ji , Boo Hye-Jin , Lee Ho Jin , Min Hye-Young , Lee Ho-Young
Published: April 2023

Supplementary materials and methods. Supplementary Table 1. Experimental schedule for the chronic unpredictable stress (CUS). Supplementary Table 2. Primer sequences used for RT-PCR analysis. Supplementary Table 3. Primer sequences used for real-time PCR analysis.
Supplementary Figure 4 from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

ACLY downregulation in LMW-E mouse xenografts inhibits tumor growth.
Supplementary Figure legends from HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis
Authors: Choi Seo-Hyun , Nam Jae-Kyung , Kim Bu-Yeo , Jang Junho , Jin Young-Bae , Lee Hae-June , Park Seungwoo , Ji Young Hoon , Cho Jaeho , Lee Yoon-Jin
Published: April 2023

Supplementary Figure legends
Supplementary Figure 1 from RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3
Authors: Xie Min , Vesuna Farhad , Tantravedi Saritha , Bol Guus M. , Heerma van Voss Marise R. , Nugent Katriana , Malek Reem , Gabrielson Kathleen , van Diest Paul J. , Tran Phuoc T. , Raman Venu
Published: April 2023

Histogram displaying results of shDDX3 rescue experiment