bluuebunny/crossref_metadata_2025 huggingface dataset:
Problems of violation of the rights of borrowers under the consumer loanagreement
Authors:   Osman A. Osmanov Dagestan State University, Osmanov Osman A.
Published: February 2023

The article analyzes the problems of legal protection of borrowers under a consumer loanagreement. The author examines the issue from the point of view of the application of consumer protectionlegislation.Certain problems of legal regulation and ways to overcome them are identified. The judicial practiceisanalyzed,which indicates an insufficient level of legal protection in this area and the creditor's abuse of his positionasaneconomically strong party in legal relations.
Problems of implementation of legislation on state social assistance on the basis of asocial contract
Authors:   Amina G. Magomedova Dagestan State University, Magomedova Amina G.
Published: February 2023

The article examines the implementation of a new, more effective formof social support forpoorcitizens - the social contract. The features of such an agreement that distinguish it fromtraditional formsofstatesocial assistance are outlined. The judicial practice is analyzed, which reflects the problems that ariseduringthepreparation and implementation of the social adaptation program. The role of regional and municipal authoritiesisemphasized, which has the opportunity to take into account both the needs of citizens andthe causesofpovertycharacteristic of a particular region and offer the most acceptable options for overcoming them. Theconclusionsemphasize that the criteria for the effectiveness of this form of social assistance are determinednot somuchbyquantitative parameters as by qualitative ones. Therefore, the indicators of a positive result will beovercomingtheexisting difficult life situation and obtaining an independent income. Another problemis the lackof awarenessofcitizens about the availability of such a form of social support, about the possibilities of a social contract andtheprocedure for implementing its conditions, which requires the social protection authorities tocarryout information and explanatory work.
On the type material of the Upper Ordovician mitrate “carpoid” Diamphidiocystis drepanon Kolata & Guensburg (Echinodermata: Stylophora)
Authors: Heads Sam , Kolata Dennis , Guensburg Thomas
Published: February 2023

We document the formal transfer of the holotype, seven paratypes, and two referred specimens of the mitrate “carpoid” Diamphidiocystis drepanon Kolata & Guensberg (Echinodermata: Stylophora) from the Department of Geology, Southern Illinois University (SIU) to the paleontological collection of the Illinois State Geological Survey (ISGS) at the PRI Center for Paleontology. A tabulated list of the specimens cross-referenced with their new ISGS numbers is provided. The specimens come from the Cincinnatian (Upper Ordovician) Orchard Creek Shale (Maquoketa Group) near Thebes in Alexander County, southern Illinois.
Perspectives of Patients With Orthopedic Trauma on Fully Automated Digital Physical Activity Measurement at Home: Cross-sectional Survey Study
Authors: Scherer Julian , Yogarasa Vithush , Rauer Thomas , Pape Hans-Christoph , Heining Sandro-Michael
Published: February 2023

Background

The automated digital surveillance of physical activity at home after surgical procedures could facilitate the monitoring of postoperative follow-up, reduce costs, and enhance patients’ satisfaction. Data on the willingness of patients with orthopedic trauma to undergo automated home surveillance postoperatively are lacking.

Objective

The aims of this study were to assess whether patients with orthopedic trauma would be generally willing to use the proposed automated digital home surveillance system and determine what advantages and disadvantages the system could bring with it.

Methods

Between June 2021 and October 2021, a survey among outpatients with orthopedic trauma who were treated at a European level 1 trauma center was conducted. The only inclusion criterion was an age of at least 16 years. The paper questionnaire first described the possibility of fully automated movement and motion detection (via cameras or sensors) at home without any action required from the patient. The questionnaire then asked for the participants’ demographics and presented 6 specific questions on the study topic.

Results

In total, we included 201 patients whose mean age was 46.9 (SD 18.6) years. Most of the assessed patients (124/201, 61.7%) were male. Almost half of the patients (83/201, 41.3%) were aged between 30 and 55 years. The most stated occupation was a nine-to-five job (62/199, 30.8%). The majority of the participants (120/201, 59.7%) could imagine using the proposed measurement system, with no significant differences among the genders. An insignificant higher number of younger patients stated that they would use the automated surveillance system. No significant difference was seen among different occupations (P=.41). Significantly more young patients were using smartphones (P=.004) or electronic devices with a camera (P=.008). Less than half of the surveyed patients (95/201, 47.3%) stated that they were using tracking apps. The most stated advantages were fewer physician visits (110/201, 54.7%) and less effort (102/201, 50.7%), whereas the most prevalent disadvantage was the missing physician-patient contact (144/201, 71.6%). Significantly more patients with a part-time job or a nine-to-five job stated that data analysis contributes to medical progress (P=.047).

Conclusions

Most of the assessed participants (120/201, 59.7%) stated that they would use the automated digital measurement system to observe their postoperative follow-up and recovery. The proposed system could be used to reduce costs and ease hospital capacity issues. In order to successfully implement such systems, patients’ concerns must be addressed, and further studies on the feasibility of these systems are needed.
Virtual Reality for Chronic Pain Management Among Historically Marginalized Populations: Systematic Review of Usability Studies
Authors: Dy Marika , Olazo Kristan , Lisker Sarah , Brown Ellenor , Saha Anindita , Weinberg Jessica , Sarkar Urmimala
Published: February 2023

Background

Virtual reality (VR) has potential to improve chronic pain management outcomes. However, the majority of studies assessing VR are conducted in predominantly White populations in well-resourced settings, thus leaving a gap in knowledge of VR use among diverse populations who experience a significant chronic pain burden.

Objective

This review aims to examine the extent to which usability of VR for chronic pain management has been studied within historically marginalized patient groups.

Methods

We conducted a systematic search to identify studies with usability outcomes located in high-income countries that included a historically marginalized population, defined by a mean age greater than or equal to 65 years, lower educational attainment (greater than or equal to 60% having attained high school education or less), and being a racial or ethnic minority (less than or equal to 50% non-Hispanic White people for studies based in the United States).

Results

Our analysis included 5 papers, which we used to conduct a narrative analysis. Three studies examined VR usability as a primary outcome. All studies assessed VR usability using different measures, of which 4 found VR to be usable by their respective study population. Only 1 study found a significant improvement in pain levels post–VR intervention.

Conclusions

The use of VR shows promise for chronic pain management, but few studies include populations that are older, have limited educational attainment, or have racial or ethnic diversity. Additional studies with these populations are needed to further develop VR systems that work best for diverse patients with chronic pain.
Can women reduce the gap to men in IRONMAN® triathlon with increasing age? –
An internet-based cross-sectional study investigating more than 690,000 race records (Preprint)
Authors: Knechtle Beat , Valero David , Villiger Elias , Thuany Mabliny , Andrade Marilia , Cuk Ivan , Nikolaidis Pantelis , Weiss Katja
Published: February 2023

BACKGROUND

The sex difference in athletic performance has been thoroughly investigated in single sport disciplines such as swimming, cycling, and running. In contrast, only small samples of long-distance triathlons, such as the IRONMAN® triathlon, have been investigated so far.

OBJECTIVE

The aim of the study was to examine a potential sex difference in the three split disciplines by age groups in 5-year intervals in a very large data set of IRONMAN® age group triathletes.

METHODS

Data from 694,769 (557,839 men and 136,930 women) IRONMAN® age group triathletes (in 5-year intervals from 18-24 to 75+ years) finishers between 2002 and 2022 in all official IRONMAN® races worldwide were analyzed. The sex differences in performance between women and men were determined for each split discipline and overall race performance.

RESULTS

Most finishers were in the age group 40-44 years. The fastest women were in the age group 25-29 years, and the fastest men were in the age group 30-34 years. For all split disciplines and overall race time, men were always faster than women in all groups. The sex difference was more significant in cycling compared to swimming and running. From the age group 35-39 years until 60-64 years, the sex differences were nearly identical in swimming and running. For both women and men, the sex difference was least significant in the age group 18-24 years for all split disciplines and increased in a U-shaped manner until the age group 70-74 years. For the age groups 75 years and older, the sex difference decreased in swimming and cycling but increased in running.

CONCLUSIONS

The sex difference in the IRONMAN® triathlon was least significant in the age group 18-24 years for all split disciplines and increased in a U-shaped manner until the age group 70-74 years. For 75 years and older, the sex difference decreased in swimming and cycling but increased in running.

CLINICALTRIAL

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Debate: Intermittent Hemodialysis versus Continuous Kidney Replacement Therapy in the Critically Ill Patient: Moderator Commentary
Authors: Palevsky Paul M.
Published: February 2023

The selection of modality of kidney replacement therapy (KRT) has been debated for decades. Although the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Acute Kidney Injury considers intermittent hemodialysis and continuous KRT (CKRT) to be complementary therapies, with a recommendation to preferably use CKRT in hemodynamically unstable patients, there is a vocal cadre of practitioners and investigators who argue that CKRT is the only modality that should be used to support critically ill patients with AKI, relying on observational data to argue that intermittent hemodialysis is associated with impaired recovery of kidney function. In this issue of CJASN, we have provided a virtual debate allowing advocates for and against the use of intermittent hemodialysis to make their best cases. In the end, their arguments converge, with a call for more data and a pragmatic, patient-focused approach to the delivery of KRT to critically ill patients with AKI.
Las prácticas químicas a través de sus transformaciones
Authors: Chamizo Guerrero José Antonio
Published: February 2023

A partir de los “ejemplares” kuhnianos, lo que significa incorporar los instrumentos en los procesos de cambio, y sustituir el concepto de revolución por el de transformación, se describe la construcción y el desarrollo de la química identificando su método particular: análisis y síntesis. Todo ello acompañado por el surgimiento de nuevas subdisciplinas y de nuevas entidades u objetos epistémicos, que acumuladas, se fueron integrando en los robustos ejemplares de sus cambiantes prácticas, al mismo tiempo que se introdujeron importantes modificaciones industriales.
Respons Kepuasan Pengunjung dan Strategi Pengembangan Agrowisata Gamboeng
Authors: Hasna Athallah Najla  , Kralawi Sita
Published: February 2023

Agrowisata Gamboeng merupakan salah satu objek wisata yang berlokasi di Kampung Gambung, Desa Mekarsari, Kecamatan Pasirjambu, Kabupaten Bandung. Tempat wisata ini dikelola oleh Pusat Penelitian Teh dan Kina Gambung. Penelitian ini bertujuan untuk mengetahui respons pengunjung Agrowisata Gamboeng dan mengetahui strategi pengembangan yang tepat bagi Agrowisata Gamboeng dengan Matriks IFE, Matriks EFE, Matriks IE dan Analisis SWOT. Data yang digunakan adalah data primer berupa kuesioner kepuasan pengunjung kepada 47 responden pengunjung dan kuesioner SWOT kepada 8 tenaga ahli Agrowisata Gamboeng. Hasil yang didapat berupa karakteristik pengunjung, distribusi kepuasan pengunjung, kepuasan pengunjung, IFE, EFE, dan perumusan strategi pengembangan yang sebaiknya diterapkan pada Agrowisata Gamboeng. Analisis respons pengunjung menunjukkan pengunjung puas terhadap pelayanan Agrowisata Gamboeng dengan aspek kepuasan terbaik adalah keindahan Agrowisata Gamboeng sedangkan aspek kepuasan terburuk adalah dari akses infrastruktur menuju Agrowisata Gamboeng. Penetapan strategi menggunakan IE menunjukkan posisi dari perusahaan berada pada kuandran I yang dapat digambarkan tumbuh dan membangun (growth and build) maka strategi yang sebaiknya digunakan perusahaan dalam menjalankan bisnisnya adalah strategi yang intensif dan integratif. Pada analisis SWOT Agrowisata Gamboeng berada pada kuadran II sehingga strategi yang perlu diterapkan adalah strategi diversifikasi.
A Study on the combined-law clause in Islamic financial contract
Authors:   Wonkwang University Legal Research Institute has, Sohn Tae-Woo , Kim Bun-Tae
Published: February 2023

The rapid growth of Islamic finance lead to a rise in the number of disputes that implicate Islamic law(Shaira). Even though the primary law of Islamic finance contract can be that of a common law or civil law country, the implication of Sharia still remains. There is a resistance by some courts to apply Sharia to contracts which invoke another national law. This judgment is based on the principle that only one law can govern a contract and the Rome Convention’s requirement that the law of a contract be that of a national system. Scholars also support these conclusions by general precepts of common law and legal reasoning. In spite of these firm statements from courts and scholars, the practice of arbitral tribunal judging matters of Islamic finance has been to apply the principles of Sharia to fulfill the intent of the parties, who used Islamic financial instruments instead of conventional bank products. There are also cases showing that U.S. courts and European arbitrators are willing to use Sharia.
If judges do not understand the reasoning of Islamic finance practice in incorporating Sharia, just like Shamil Bank v. Beximco Pharmaceuticals case, the result greatly hampers the growth of Islamic finance industry as well as the bad prejudice of Islamic law. As Islamic finance arbitrations consistently show a reliance on the use of national law with Sharia, western courts should judge the dispute to the greatest extent possible in accordance with the chosen national law, and only resort to applying Shariah principles as a gap-filler or when Islamic law sources are the basis of the specific issue being raised.
A Study on the Consistency of Legal System of ‘Registered Security Guard’ Law
Authors:   Wonkwang University Legal Research Institute has, Cho Sung Kyu
Published: February 2023

According to the REGISTERED SECURITY GUARD ACT, the registered security guard are required to perform the duties prescribed in the Police Officer's Job Execution Act, and in that respect, the character of a public administration performer is remarkable in terms of duties, while the working relationship of the registered security guard is basically similar to the employment relationship of private law. For that reason, the legal issue surrounding the registered security guard brings legal ambiguity in various aspects.
This problem situation is especially remarkable in the case of registered security guard working in the public sector, in that the employer is the administrative entity of the state or local government, as well as the public administrative nature of the work. On the other hand, in the case of petition police working outside the public sector, the legal problem is more pronounced in that the REGISTERED SECURITY GUARD ACT is generally applied due to its status as a registered security guard, even though the characteristics of private law are very strong in the nature of labor relations. In particular, the registered security guard in the private sector are the cause of legal ambiguity compared to general labor relations of private law in that they are substantially similar to the security work under the Security Services Industry Act, which is the subject of the permission system.
In Korean legislation that presupposes the distinction between public law and private law, the distinction between public law and private law needs to be distinguished in various aspects, such as differences in legal relations and applicable laws, so it is necessary to secure legal systematic consistency corresponding to this in the registered security guard law system.
The REGISTERED SECURITY GUARD ACT is intended to be a general and complete discipline for the registered security guard system, but the actual regulations are mostly fragmentary and individual regulations for solving phenomenal problems, not consistent systematic legal principles, even so, public law and judicial characteristics are mixed, so this situation is the cause of ambiguity in the interpretation and application of the law.
For this reason, it is necessary to improve the petition police law, regarding the direction of improvement, considering Korea's legal system based on the distinction between public and private law, it is logical and consistent to legal system to classify the legal relationship of a person who is performing public administrative work through employment relations in the public sector into public law relations. Therefore, it is a reasonable direction to improve the legislation to separate and regulate the registered security guard working in the public sector which inevitably have strong public legal characteristics and the registered security guard working in the private sector with significantly less public legal characteristics.
Why Do Indian Surrogate Mothers Still Remain in Poverty?
Authors: Kuan-Ju Chen
Published: February 2023

After the release of new Surrogacy (Regulation) Bill in 2020, surrogate
mothers in India showed greater concerns over the rights to their
bodies. Despite receiving economic compensation from the intending
parents, surrogates have failed to convert their income into greater
well-beingness. In understanding what Sen (1999) claimed as
Capability Poverty, the research investigated the concept through
a dynamic interaction analysis of Bourdieu (1984)’s Capital
formation throughout the contracted pregnancy, contributing to the
surrogacy literature a novel ground in depicting a more dynamic capital
formation. The inconvertibility of economic capital for social,
cultural, and emotional capital proved a continued suffering for
surrogates, including both physical exploitations due to oppressive
medical settings and psychological burdens from stigmatisation
(re)produced from the traditional values and geographies of class. In
debating over whether surrogates possess actual ability to exercise
their agency over structure, it is essential that this research reminds
once again their choices over work are not made in isolation from
socioeconomic and cultural factors.
A numerical method for solving the space fractional Navier-Stokes equations
Authors: Jiang Wei , Yue Zihan , Chen Zhong , Wu Boying , Zhang Biao
Published: February 2023

In this work, bases on the reproducing kernel theory and collocation
method, we study the space Riesz fractional Navier-Stokes equations, and
propose the numerical method to solve it. Firstly the new base space can
be constructed by the spline and reproducing kernel space. The
ε-approximate solution in binary spline space in the form of
finite terms can be derived. Through using the collocation method, the
approximate problem is solved. In addition, we provide analysis of the
stability and convergence. In final, two numerical examples are provided
to show the effectiveness of our method.
Writing-reading attainments onto underlying gaps and bonds as prone to communication skills follow-up
Authors: Olmos Jonathan , Garcia Andres
Published: February 2023

This study aimed to look into the impact of educational practices on the
reading and writing skills of learners, with a specific focus on the
gaps and bonds in EFL learning while communication skills carried
follow-ups. The study employed a mixed methodology, which embraced
communication contexts placed in the teaching process, and
self-perceptions of the participants in a multidimensional communication
axis to collect data via surveys, observational forms and exploratory
statistics. The results indicate that while there is a stable level of
variation in terms of reading and writing achievement, there are
setbacks in certain areas such as fill-in-the-blank questions in complex
activities and sentence rewriting tasks. Additionally, the study found
that providing students with picture clues can improve their
performance. The study also suggests that blending both reading and
writing skills in activities can lead to large linkages and improvements
in performance.
Is the Madden-Julian Oscillation a Moisture Mode?
Authors: Mayta Victor C. , Adames-Corraliza Ángel F.
Published: February 2023

The governing thermodynamics of the Madden-Julian Oscillation (MJO) are
examined using sounding and reanalysis data. On the basis of four
objective criteria, results suggest that the MJO behaves like a moisture
mode –a system whose thermodynamics is governed by moisture– only over
the Indian Ocean. Over this basin, the small effective gross moist
stability, i.e., a slow moist static energy (MSE) export by convection,
and slow convective adjustment timescale allows moisture modes to exist
for all zonal wavenumbers except 1. Elsewhere, the faster-propagating
wavenumber 1-2 components are more prominent and the effective gross
moist stability is higher, preventing weak temperature gradient (WTG)
balance to be established and causing temperature and moisture to play
similar roles in the MJO’s thermodynamics.
A New Four-Component L*-dependent Model for Radial Diffusion based on Solar Wind and Magnetospheric Drivers of ULF Waves
Authors: Murphy Kyle Robert , Sandhu Jasmine Kaur , Rae I. Jonathan , Daggitt Thomas Alexander , Glauert Sarah A , Horne Richard B. , Watt Clare E. J. , Bentley Sarah N , Kellerman Adam C , Ozeke Louis Godwin , Halford Alexa J. , Tian Sheng , Breneman Aaron , Olifer Leonid , Mann Ian , Angelopoulos Vassilis , Wygant John
Published: February 2023

Waves which couple to energetic electrons are particularly important in
space weather, as they drive rapid changes in the topology and intensity
of Earth’s outer radiation belt during geomagnetic storms. This includes
Ultra Low Frequency (ULF) waves that interact with electrons via radial
diffusion which can lead to electron dropouts and rapid acceleration and
inward transport of electrons during. In radiation belt simulations, the
strength of this interaction is specified by ULF wave radial diffusion
coefficients. In this paper we detail the development of new models of
electric and magnetic radial diffusion coefficients derived from in-situ
observations of the azimuthal electric field and compressional magnetic
field. The new models use L* as it accounts for adiabatic changes due to
the dynamic magnetic field coupled with an optimized set of four
components of solar wind and geomagnetic activity, Bz, V, Pdyn and
Sym-H, as independent variables (inputs). These independent variables
are known drivers of ULF waves and offer the ability to calculate
diffusion coefficients at a higher cadence then existing models based on
Kp. We investigate the performance of the new models by characterizing
the model residuals as a function of each independent variable and by
comparing to existing radial diffusion models during a quiet geomagnetic
period and through a geomagnetic storm. We find that the models
developed here perform well under varying levels of activity and have a
larger slope or steeper gradient as a function of L* as compared to
existing models (higher radial diffusion at higher L* values).
Potential Impacts of Energy and Vehicle Transformation through 2050 on the Atmospheric Environment of Japan: focus on PM2.5 Metals and Aerosol Acidity inducing Respiratory Inflammation
Authors: Kayaba Satoko , Kajino Mizuo
Published: February 2023

The impacts of renewable energy shifting, passenger car electrification,
and lightweighting through 2050 on the atmospheric concentrations of
PM2.5 total mass, Fe, Cu, and Zn, and aerosol acidity in Japan were
evaluated using a regional meteorology–chemistry model. We focus on the
changes in on-road exhaust/non-exhaust and upstream emissions. The
domestic primary emissions of PM2.5, Fe, Cu, and Zn were reduced by 9%,
19%, 18%, and 10%, and their surface concentrations in the urban area
decreased by 8%, 13%, 18%, and 5%, respectively. On a PM2.5 mass
basis, battery electric vehicles (BEVs) have been considered to have no
advantage in non-exhaust PM emissions because the increased tire and
road wear and resuspension due to their heavy weight offset the benefit
of brake wear reduction by regenerative brake. Indeed, passenger car
electrification without lightweighting also did not significantly reduce
PM2.5 concentration in urban area in this study (-2%) but was highly
effective in reducing Fe and Cu concentrations owing to their high brake
wear dependence (-8% and -13%, respectively). Furthermore, the
lightweigting of the drive battery and the body frame of BEVs reduced
even tire and road wear and resuspension. Therefore, vehicle
electrification and lightweighting could effectively reduce the risks of
respiratory inflammation. The reduction of SOx, NOx, and NH3 emissions
changed aerosol acidity in urban area (maximum pH ±0.2). However,
changes in aerosol acidity only slightly changed water-soluble metal
concentrations (maximum +2% for Fe and +0.5% for Cu and Zn);
therefore, it is important to focus on reducing primary metal emissions.
New record for mycobiota of Serbia: A rare fungus Quambalaria cyanescens found in Pelophylax esculentus (Anura) skin microbiome
Authors: Stupar Milos , Savkovic Zeljko , Breka Katarina , Krizmanic Imre , Stamenkovic Srdjan , Vukojevic Jelena , Ljaljevic-Grbic Milica
Published: February 2023

A rare basidiomycete Quambalaria cyanescens, documented so far on various
substrates worldwide, was isolated from the skin of edible frog (Pelophylax
esculentus) captured in South Banat. The fungal identification was based on
sequencing of ITS region and BLAST analyses. The presence of Q. cyanescens
in the amphibian skin microbiome is not only the first finding of this
fungus in Serbia but also the recording of new ecological habitat for this
rare species of micromycetes. Phylogenetic analyses revealed the high
similarity of isolate in this study with foliar pathogens of Eucalyptus in
Australia.
Variation of harvest index of wheat and triticale in monocrops and intercrops system of cultivation
Authors: Grcak Milosav , Grcak Dragan , Jevtic Radivoje , Lalosevic Mirjana , Zupunski Vesna , Orbovic Branka , Knezevic Desimir
Published: February 2023

The harvest index of grain can be used as indicator for the potential yield
of crop. The aim of this study was to determine the variation of the harvest
index for wheat and triticale and differences in monocrops and intercrops
systems of cultivation under different field environmental conditions. The
experiment, carried out in field conditions for two consecutive years, was
designed according to a randomized block system so that each species was
sown in two cultivation systems as a single crop and a combined crop (wheat
+ pea and triticale + pea) in four replicates. The results show that, in the
first year of the experiment, the value of the harvest index varied from
32.5% (triticale + pea) to 39.3% (wheat monocrop), while in the second year
of the research, the value of the harvest index varied from 26.4% (wheat +
pea) and 28.1% (triticale + pea). As for the components of harvest index,
values of weight of grains spike-1 and weight of total above ground biomass
were higher in intercrops than in monocrops system of cultivation. It can be
concluded that the intercropping of cereals (triticale and wheat) and forage
crops (pea) provided positive effects on weight of grains spike-1 and weight
of total above ground biomass and does not diminish harvest index when
compared to standard system of cultivation.
Hypericum perforatum L. extracts exert cytotoxic effects and show different miRNA signatures in PC-3 and DU 145 prostate cancer cells
Authors: Petrovic Nina , Ergün Sercan , Djordjic-Crnogorac Marija , Stanojkovic Tatjana , Malisic Emina , Matic Ivana
Published: February 2023

Phytochemicals and bioactive substances derived from a wide range of plant extracts have been reported to exert various anticancer effects. Prostate cancer is one of the leading causes of cancer-related deaths within the male population. Prostate cancer-specific miRNA signatures were associated with cancer formation and progression, with various subtypes, and response to therapy. MicroRNA levels of expression were shown to change after the treatment of various compounds and substances extracted from natural products. Natural herbal compounds were shown to induce variations in miRNA expression levels in cancer cells. The aims of this study were to investigate the cytotoxic effects of methanol, ethyl-acetate, and hexane extracts obtained from branch-body part and flowers of Hypericum perforatum L. against humane PC-3 and DU 145 and to test potential miRNA-128/133b/155/193a/206/21/335 signature changes and differences between the two prostate cancer cell lines. Cytotoxic activity of H. perforatum extracts, their effects on cell cycle distribution, and miRNA expression levels were examined in humane PC-3 and DU 145 prostate cancer cells by MTT cell survival assay, flow cytometry, and quantitative real-time PCR. Hexane extract of flowers showed the strongest intensity of cytotoxic activity against PC-3 and DU 145 cells. The highest increase in the percentage of PC-3 cells in the subG1 phase was observed in cell samples treated with hexane extract of flowers and branch-body part. Significant differences in miRNA-128/133b/155/193a/206/21/335 levels were observed between PC-3 and DU 145 cell lines, especially in samples treated with flower extracts compared with the branch-body part. Conclusions: Investigated extracts have significant anticancer potential not only from the aspects of cytotoxicity and cell cycle effects but also from the aspect of lowering oncogenic or increasing tumor-suppressive miRNAs. The best effect might be the increase of tumor-suppressive miR-128 (accompanied by miR-193a) induced by the hexane extract of the flowers, which also exerted the highest cytotoxic activity. Hexane extract of flowers may be the candidate for further investigation for improving the efficiency of standard therapies for PCa. A miRNA signature might be cell-type specific after the treatment with H. perforatum extracts.
Variability in antioxidants in yellow, white, and red coloured maize grain in response to different fertilizers
Authors: Dragicevic Vesna , Simic Milena , Tolimir Miodrag , Djuric Nenad , Senk Milena , Stankovic Goran , Brankov Milan
Published: February 2023

Maize (Zea mays L.) grain is an important source of nutrients in human diet.
The differences in content and relations between certain components of maize
grain impact grain colour and its nutritional quality. The objective of the
Study was to examine effects of different fertilization systems: mineral
fertilizer (urea), organic fertilizer, and bio-fertilizer on white, yellow,
and red coloured maize hybrids, regarding grain yield and variations in
content of antioxidants: phytate, phenolic compounds, glutathione,
carotenoids (yellow pigment), and reduction capacity of DPPH radical.
Two-fold higher average grain yield and double fold lower concentration of
phenols and carotenoids were present in 2018, in comparison to drier 2017.
The lowest phytate content and the highest values of phenols and DPPH
reduction capacity were present in red maize kernel, as a hybrid with the
highest yield, while in yellow maize kernel, the highest values of yellow
pigment and glutathione occurred. The bio-fertilizer expressed the positive
impact on reduction of phytate concentration and increase of phenols
concentration in maize grain, while urea increased concentration of yellow
pigment and glutathione. Correlation analysis showed that reduction in
phytate and carotenoids was significant and positive related with grain
yield increase, while phenols showed positive correlation with reduction
capacity of DPPH radical. Thus, it was shown that changes in fertilization
methods could affect antioxidants status in maize grain, particularly in red
coloured maize, which besides high yield potential, possess remarkable
higher antioxidant capacity in regard to yellow and white coloured maize.
PPARGC1A gene polymorphism and its association with obesity-related metabolic traits in Serbian adolescent population
Authors: Vidovic Vanja , Maksimovic Nela , Vidovic Stojko , Damnjanovic Tatjana , Milovac Irina , Novakovic Ivana
Published: February 2023

PPARGC1A is involved in many metabolic processes including normal
mitochondrial biogenesis, oxidation of glucose and lipids and transport of
glucose into skeletal muscles. Previous researches linked this polymorphism
with the higher risk of developing type 2 diabetes, metabolic syndrome and
obesity. The aim of the study was to investigate the association of
Gly482Ser with body mass index (BMI), fasting glucose levels and lipid
profile in Serbian adolescents. The study included 147 boys and 150 girls,
15 years of age. Anthropometric and biochemical parameters were recorded.
Cardiovascular and malignant diseases, type 2 diabetes, cerebral palsy and
genetics syndrome were criteria for exclusion. Genotyping was performed by
polymerase chain reaction-restriction fragment length polymorphism (RFLP)
assay. The results showed that boys carriers of GG genotype had
statistically higher mean values of TC compared to the boys who were
carriers of GA+AA genotypes (p=0.033). However, statistical significance was
not obtained for the other analyzed parameters. Furthermore, in the group of
overweight and obese children, higher mean values of TC and LDL-C were
observed in the carriers of GG genotype compared to carriers of GA+AA
genotype for all the adolescents, as well as in the group of girls. No
correlation was observed for values of BMI, fasting blood glucose and levels
of triglycerides. To confirm these results, further research with larger
sample size and non-genetics factor taking into consideration, would be of
great interest.
Variability of some traits of walnuts (Juglans regia L.) in the test of half sib, originating in the Djerdap forest
Authors: Kovac Milica , Kovacevic Branislav , Orlovic Sasa
Published: February 2023

As part of efforts for protection and restoration of variability of Juglans
regia in Djerdap gorge, Serbia, where it grows as autochthonous relict
species, the variability of ten measured and nine derived leaf morphometric
parameters of half-sib progenies Persian walnut originating from Djerdap
gorge was studied in this work. According to the contribution to total
expected variance, parameters that were most effected by differences between
half-sib progenies are leaf width (LW), side leaflet length (lL) and top
leaflet length (20-30%). Using loadings with the first four rotated
principal components, describing 90.1% of total variance, all parameters
were grouped in four groups, where parameters LW, lL and lt were in the
first group, suggesting multicollinearity between them. These parameters had
also relatively high loadings with the first canonical variable from
canonical discriminant analysis. Only one of them (lt) was selected by
forward stepwise discriminant analysis, where model with four selected leaf
parameters achieved 26.5% of correct allocation, while model with all
studied parameters achieved 62.4% of correct allocation. Half-sib progenies
agglomerated in three clusters, where two small clusters originate from
trees that were close to sheltered valleys of small tributaries to river
Danube, opposite to mother trees of the first cluster progenies, that were
exposed to dominant winds.
Use of linear modeling, multivariate adaptive regression splines and decision trees in body weight prediction in goats
Authors: Yakubu Abdulmojeed , Eyduran Ecevit , Celik Senol , Ishaya Juliana
Published: February 2023

Use of robust regression algorithms for better prediction of body weight (BW) is receiving increased attention. The present study therefore aimed at predicting BW from chest circumference, breed and sex of a total of 1,012 goats. The animals comprised 332 matured West African Dwarf (WAD) (197 bucks and 135 does), 374 Red Sokoto (RS) (216 bucks and 158 does) and 306 Sahel (SH) (172 bucks and 134 does) randomly selected in Nasarawa State, north central Nigeria. BW prediction was made using automatic linear modeling (ALM), multivariate adaptive regression splines (MARS), classification and regression tree (CART), chi-square automatic interaction detection (CHAID) and exhaustive CHAID. The predictive ability of each statistical approach was measured using goodness of fit criteria i.e. Pearson?s correlation coefficient (r), Coefficient of determination (R2), Adjusted coefficient of determination (Adj. R2), Root-mean-square error (RMSE), Mean absolute percentage error (MAPE), Mean absolute deviation (MAD), Global relative approximation error (RAE), Standard deviation ratio (SD ratio), Akaike?s information criterion (AIC) and Akaike?s information criterion corrected (AICc). Male RS and SH goats had significantly (P<0.05) higher BW and CC compared to their female counterparts while in WAD, male goats had significantly (P<0.05) higher CC (57.88?0.51 vs. 55.45?0.55). CC was determined to be the trait of paramount importance in BW prediction, as expected. Among the five models, MARS algorithm gave the best fit in BW prediction with r, R2, Adj. R2, SDratio, RMSE, RAE, MAPE, MAD, AIC and AICc values of 0.966, 0.933, 0.932, 0.26, 1.078, 0.045, 3.245, 0.743, 186.0 and 187.0, respectively. The present information may guide the choice of model which may be exploited in the selection and genetic improvement of animals including feed and health management and marketing purposes, and especially in the identification of the studied breed?s standards.
Characteristics of newly created grapevine varieties Vozd and Vladun
Authors: Nikolic Dragan , Rankovic-Vasic Zorica , Petrovic Aleksandar , Matijasevic Sasa , Lisov Nikolina , Plavsic Ivana
Published: February 2023

This paper presents the most important morphological and
production-technological characteristics of newly created grapevine
varieties Vozd and Vladun, intended for the production of red wines. The
newly created varieties were compared with the standard variety Cabernet
Sauvignon during the three-year period of testing (2015-2017) in the
relation studied properties. The variety Vozd obtained from the crossing
combination Zacinak x Prokupac, and the variety Vladun from the crossing
combination Merlot x Zupski Bojadiser. The investigated varieties differed
considerably in terms of some morphological traits and represents unique
genotypes. The newly recognized varieties have a hermaphrodite type of
flower, dense bunch, globose berry shape and blue black color of berry skin.
The yield, bunch weight, bunch length and bunch width were higher at both
varieties than for the standard variety. The Vozd variety had a yield of
1.29 kg/m2 and a bunch weight of 174.3 g, and the Vladun variety had a yield
of 0.87 kg/m2 and a bunch weight of 153.7 g. For the standard variety the
grape yield was 0.78 kg/m2 and the bunch weight was 134.0 g. The content of
sugar and total acids in the must of the Vozd variety was 20.5% and 6.5 g/l,
while for the Vladun variety it was 21.8% and 6.0 g/l respectively. Wine of
both varieties was drinkable, harmonious, with a specific varietal of smell
and taste and contained 12.1 vol. % of alcohol (Vozd variety), or 12.6 vol.
% of alcohol (Vladun variety). Due to the many positive features of the
grapes and wines from the Vozd and Vladun varieties, their spread to the
production vineyards of Serbia is expected.
The Duty to Consult in Canada Post-Haida Nation
Authors: Bankes Nigel
Published: February 2023

This article is intended as a companion piece to Øyvind Ravna’s contribution to this anniversary volume. It maps the development of the duty to consult in Canadian law since the seminal decision of the Supreme Court of Canada in Haida Nation v British Columbia in 2004. The article begins by briefly examining the first references to the duty to consult in 1990 before turning in Part 2 to the transformation of the duty in Haida Nation and a doctrinal analysis of the various elements of the duty. Part 3 examines the international standard of free, prior and informed consent (FPIC) as developed in the UN Declaration on the Rights of Indigenous Peoples as well as the implications of legislation that aims to give effect to the Declaration in federal or provincial law. The conclusion to the paper offers some comparative comments on Norway and Canada regarding the development of the duty to consult. These comments emphasise that whereas consultation and FPIC obligations in Norway are firmly rooted in international law, and, in particular, in the International Labour Organization’s Convention on Indigenous and Tribal Peoples (ILO C-169), this is not the case in Canada. In Canada, the duty to consult and accommodate finds its origins in domestic law and the entrenchment of aboriginal rights in the Constitution in 1982. However, more recent discussions over the implementation of the UN Declaration in federal and provincial law have inevitably broadened the discourse to include international law and the FPIC standard.
Bibliografia comentada sobre ensino de Sociologia
Authors: Baron Engerroff Ana Martina , Wilhelms Eras Lígia
Published: February 2023

Apresentação de um conjunto de referências bibliográficas que tratam sobre o ensino de Sociologia.
Dimensões identitárias do Enem sob a percepção de docentes e discentes de escolas públicas
Authors: Almeida Vitor Sergio de , Silva Maria Vieira , Richter Leonice Matilde
Published: February 2023

A centralidade atribuída ao Exame Nacional do Ensino Médio (Enem) como política de Estado, indutora de currículos, reformas educacionais e práticas docentes, tem produzido efeitos significativos na organização do trabalho escolar. O presente artigo discute o papel desse exame a partir das percepções de docentes e discentes – principais sujeitos que conferem materialidade a essa política pública. Os processos investigativos pautaram-se em uma abordagem quanti-qualitativa, a partir de dados coletados por meio de questionários e entrevistas com discentes e docentes de escolas públicas. O estudo evidenciou que a maioria dos sujeitos da pesquisa não possui informações sobre a natureza do exame e suas ações derivadas. Além disso, a pesquisa documental e bibliográfica permitiu-nos constatar oscilações identitárias do Enem entre os processos de avaliação externa e as sete funções atribuídas ao exame.
《離騷》、《九歌》貌詞研究
Authors: 陳 雄根
Published: February 2023

LANGUAGE NOTE | Document text in Chinese; abstract also in English.
《離騷》、《九歌》運用大量描繪性的詞語來狀物寫情，王逸注《楚辭》，每以「XX貌」來解釋這類詞。 近人將這類詞劃入形容詞或副詞，然而，從《離騷》、《九歌》文例觀之，這類詞既不是形容詞，也不是副詞，它們是自成一類的，本文稱之為「貌詞」。
從語音形式來看，《離騷》、《九歌》貌詞有以下特色：（1）重言；（2）雙聲叠韻；（3）非雙聲叠 韻；（4）單音詞；（5）「單言+重言」；（6）「單言+雙聲疊韻」。就語法功能而言，貌詞的基本功能是作狀語，也有作定語、謂語和補語。
由於貌詞的含義有時難以確指，故同一貌詞，説者每異。認識貌詞的語音形式及語法功能，有助於理解《離騷》及《九歌》的文義。本文旨在分析貌詞的語言結構特徵，及其在句中的功能，並就個別説解不一的貌詞，重新探討其詞義。Descriptive phrases are widely used in Li-sao and Jiu-ge for object description and feelings expression. Wang Yi （王逸）'s annotation of Chu-ci （楚辭）always explains these phrases with "appearing xx" （XX貌）. Recently, scholars take these phrases as adjectives or adverbs. However, viewing from the style of Li-sao and Jiu-ge, these phrases belong to a category other than both adjective and adverb, this paper terms them as mao-ci （貌詞）.
Viewing from their phonetic form, there are several characteristics in the mao-ci of Li-sao and Jiu-ge: （1）reduplicated form（重言）,（2）shuang-sheng （雙聲）and die-yun （疊韻）,（3）non shuang-sheng and die-yun （非雙聲疊韻）,（4） monosyllable （單音詞）,（5）single and reduplicated form （單言+重言）,（6）single form+ shuang-sheng and die-yun （單言 + 雙聲疊韻）. Viewing from their grammatical function, mao-ci basically function as adverbial, adjective, predicate and compliment.
It is often difficult to clearly define the original meaning of a specific mao-ci in Li-sao and Jiu-ge, but understanding their phonetic form and grammatical function surely helps. This paper aims to analyze the linguistic and structural characteristics of mao-ci, and investigate their function in the sentences in which they come from. Particular mao-ci that entice different interpretations will be re-examined.
Pengaruh Gratitude dan Dukungan Sosial terhadap Psychological Well-Being Wanita Dewasa Awal Bekerja yang Belum Menikah
Authors: Riszki Fitrika Ayu , Sutatminingsih Raras , Siregar Rodiatul Hasanah
Published: February 2023

Menikah adalah salah satu tugas perkembangan masa dewasa awal, namun kenyataannya saat ini banyak wanita dewasa awal belum menikah. Terdapat beberapa hal yang menjadi alasan mengapa banyak wanita yang belum menikah, salah satunya karena telah bekerja. Keadaan wanita yang bekerja tersebut membawa akibat lain bagi tugas perkembangan mereka, salah satunya adalah menikah. Kondisi tersebut terkadang memberikan dampak bagi diri mereka. Status wanita yang belum menikah tersebut terkadang akan mempengaruhi well-being mereka. Terdapat penelitian yang menyatakan wanita yang belum menikah memiliki psychological well-being yang baik, namun ada juga yang mengatakan wanita yang belum menikah memiliki psychological well-being yang kurang baik. Hal tersebut dapat terjadi karena karena kurangnya rasa syukur (gratitude) serta tidak mendapat dukungan sosial dari lingkungan sekitar. Tujuan penelitian ini adalah untuk mengetahui pengaruh gratitude dan dukungan dosial terhadap psychological well-being wanita dewasa awal bekerja yang belum menikah. Teknik pengambilan sample menggunakan snowball sampling dengan kriteria penelitian yaitu wanita bekerja yang belum menikah dan berusia 25 – 40 tahun yang berjumlah 157 orang. Skala yang digunakan dalam penelitian ini adalah skala Psychological Well-Being, Skala Gratitude dan skala Dukungan Sosial. Hasil penelitian menunjukkan bahwa gratitude dan dukungan sosial memberikan pengaruh positif secara bersama-sama terhadap psychological well-being wanita dewasa awal bekerja yang belum menikah yang artinya semakin tinggi gratitude dan dukungan sosial yang dimiliki maka semakin tinggi pula psychological well-being wanita dewasa awal bekerja yang belum menikah, dengan nilai Sig. .000.9