bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S5 from Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus–Host Protein Network
Authors: Eckhardt Manon , Zhang Wei , Gross Andrew M. , Von Dollen John , Johnson Jeffrey R. , Franks-Skiba Kathleen E. , Swaney Danielle L. , Johnson Tasha L. , Jang Gwendolyn M. , Shah Priya S. , Brand Toni M. , Archambault Jacques , Kreisberg Jason F. , Grandis Jennifer R. , Ideker Trey , Krogan Nevan J.
Published: April 2023

Genes with Combined Significance in both HPV Interaction and Genetic Alteration. Related to Figure 3.
Supplementary Material from A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor
Authors: Wang Jiawan , Yao Zhan , Jonsson Philip , Allen Amy N. , Qin Alice Can Ran , Uddin Sharmeen , Dunkel Ira J. , Petriccione Mary , Manova Katia , Haque Sofia , Rosenblum Marc K. , Pisapia David J. , Rosen Neal , Taylor Barry S. , Pratilas Christine A.
Published: April 2023

Supplementary Figure S1: Representative H&E, phospho-ERK and FISH images of pre-dabrafenib (3) and post-dabrafenib (4) tumors. Supplementary Figure S2: WES analysis of copy number variation in pre- and postdabrafenib tumors. Supplementary Figure S3: Whole copy number profiles from WES of pre- and posttreatment tumors. Supplementary Figure S4: Homology alignment of BRAF p. L514 with residues in other tyrosine kinases. Supplementary Figure S5: Relative frequency of BRAF variant alleles in SK-BT-DR cells determined by individual clone sequencing. Supplementary Figure S6: BRAF V600E/L514V reduces dabrafenib sensitivity in NIH- 3T3 cells, related to Figure 2. Supplementary Figure S7: BRAF V600E/L514V confers biochemical resistance to dabrafenib over a time course, related to Figure 2G. Supplementary Figure S8: Comparison of IC50, IC75 and IC90 of dabrafenib against A375 cells expressing BRAF V600E and BRAF V600E/L514V, related to Figure 2H. Supplementary Figure S9: The BRAF V600E/L514V double mutant promotes homodimerization, related to Figure 3A and B. Supplementary Figure S10: BRAF L514V alone is hypoactive and associated with decreased ERK signaling that is not sensitive to dabrafenib. Supplementary Figure S11: BRAF V600E/L514V is inhibited by dabrafenib in a purified kinase assay, indicating that it is not a gatekeeper mutation. Supplementary Figure S12: Quantitation of p-MEK and p-ERK immunoblots, related to Figure 4B. Supplementary Figure S13: Comparison of IC50, IC75 and IC90 of trametinib against A375 expressing BRAF V600E and BRAF V600E/L514V, related to Figure 4C. Supplementary Figure S14: The BRAF V600E/L514V mutant mediates resistance to dabrafenib that cannot be completely overcome by trametinib or dabrafenib plus trametinib, related to Figure 4D. Supplementary Figure S15: V5, p-MEK, total MEK immunoblots, and quantitation of p-ERK immunoblots, related to Figure 5A. Supplementary Figure S16: Novel RAF dimer inhibitors, MEK inhibitor and ERK inhibitor equipotently inhibit cell growth in BRAF V600E and V600E/L514V expressing cells. Supplementary Figure S17: Novel RAF dimer inhibitor, MEK inhibitor and ERK inhibitor equipotently inhibit ERK signaling in BRAF V600E and V600E/L514V expressing cells. Supplementary Figure S18: BGB3245 binds mutant BRAF V600E monomer and second site of V600E/L514V dimer with similar affinity. Supplementary Table S1: Mutations identified by WES of pre-dabrafenib and postdabrafenib tumors. Supplementary Table S2: Secondary mutations associated with acquired resistance and occurring in residues homologous with L514 in BRAF. Supplementary Table S3: BRAF L514V allele frequency determined by ddPCR.
Supplemental Table 4 from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
Authors: Zhang Maomao , Di Martino Julie S. , Bowman Robert L. , Campbell Nathaniel R. , Baksh Sanjeethan C. , Simon-Vermot Theresa , Kim Isabella S. , Haldeman Pearce , Mondal Chandrani , Yong-Gonzales Vladimir , Abu-Akeel Mohsen , Merghoub Taha , Jones Drew R. , Zhu Xiphias Ge , Arora Arshi , Ariyan Charlotte E. , Birsoy Kivanç , Wolchok Jedd D. , Panageas Katherine S. , Hollmann Travis , Bravo-Cordero Jose Javier , White Richard M.
Published: April 2023

A375 Lipidomics
Supplemental Table 1 from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
Authors: Zhang Maomao , Di Martino Julie S. , Bowman Robert L. , Campbell Nathaniel R. , Baksh Sanjeethan C. , Simon-Vermot Theresa , Kim Isabella S. , Haldeman Pearce , Mondal Chandrani , Yong-Gonzales Vladimir , Abu-Akeel Mohsen , Merghoub Taha , Jones Drew R. , Zhu Xiphias Ge , Arora Arshi , Ariyan Charlotte E. , Birsoy Kivanç , Wolchok Jedd D. , Panageas Katherine S. , Hollmann Travis , Bravo-Cordero Jose Javier , White Richard M.
Published: April 2023

A375 RNA-seq
Supplementary text_tables_figurelegends from Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Authors: Gust Juliane , Hay Kevin A. , Hanafi Laïla-Aïcha , Li Daniel , Myerson David , Gonzalez-Cuyar Luis F. , Yeung Cecilia , Liles W. Conrad , Wurfel Mark , Lopez Jose A. , Chen Junmei , Chung Dominic , Harju-Baker Susanna , Özpolat Tahsin , Fink Kathleen R. , Riddell Stanley R. , Maloney David G. , Turtle Cameron J.
Published: April 2023

Supplementary methods, figure legends, and Supplementary Table 1. Lymphodepletion regimens prior to CAR-T cell infusion; Supplementary Table 2. Neurologic adverse event terms
Figure S7 from Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Authors: Gust Juliane , Hay Kevin A. , Hanafi Laïla-Aïcha , Li Daniel , Myerson David , Gonzalez-Cuyar Luis F. , Yeung Cecilia , Liles W. Conrad , Wurfel Mark , Lopez Jose A. , Chen Junmei , Chung Dominic , Harju-Baker Susanna , Özpolat Tahsin , Fink Kathleen R. , Riddell Stanley R. , Maloney David G. , Turtle Cameron J.
Published: April 2023

Supplementary Figure 7. Blood-brain barrier disruption in severe neurotoxicity after CD19 CAR-T cell immunotherapy
Figure S6 from Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Authors: Gust Juliane , Hay Kevin A. , Hanafi Laïla-Aïcha , Li Daniel , Myerson David , Gonzalez-Cuyar Luis F. , Yeung Cecilia , Liles W. Conrad , Wurfel Mark , Lopez Jose A. , Chen Junmei , Chung Dominic , Harju-Baker Susanna , Özpolat Tahsin , Fink Kathleen R. , Riddell Stanley R. , Maloney David G. , Turtle Cameron J.
Published: April 2023

Supplementary Figure 6. Classification tree modeling to predict grade {greater than or equal to}4 neurotoxicity
Figure S5 from Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Authors: Gust Juliane , Hay Kevin A. , Hanafi Laïla-Aïcha , Li Daniel , Myerson David , Gonzalez-Cuyar Luis F. , Yeung Cecilia , Liles W. Conrad , Wurfel Mark , Lopez Jose A. , Chen Junmei , Chung Dominic , Harju-Baker Susanna , Özpolat Tahsin , Fink Kathleen R. , Riddell Stanley R. , Maloney David G. , Turtle Cameron J.
Published: April 2023

Supplementary Figure 5. Immunohistochemistry of brain in a patient with fatal neurotoxicity
Figure S2 from Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Authors: Gust Juliane , Hay Kevin A. , Hanafi Laïla-Aïcha , Li Daniel , Myerson David , Gonzalez-Cuyar Luis F. , Yeung Cecilia , Liles W. Conrad , Wurfel Mark , Lopez Jose A. , Chen Junmei , Chung Dominic , Harju-Baker Susanna , Özpolat Tahsin , Fink Kathleen R. , Riddell Stanley R. , Maloney David G. , Turtle Cameron J.
Published: April 2023

Supplementary Figure 2. Serum cytokines after CD19 CAR-T cell immunotherapy
Supplementary Table S7 from An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
Authors: Murray Christopher W. , Brady Jennifer J. , Tsai Min K. , Li Chuan , Winters Ian P. , Tang Rui , Andrejka Laura , Ma Rosanna K. , Kunder Christian A. , Chu Pauline , Winslow Monte M.
Published: April 2023

Summary of differences in Sik1-3 mRNA abundance between Lkb1-proficient and deficient contexts.
Supplementary Table S4 from An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
Authors: Murray Christopher W. , Brady Jennifer J. , Tsai Min K. , Li Chuan , Winters Ian P. , Tang Rui , Andrejka Laura , Ma Rosanna K. , Kunder Christian A. , Chu Pauline , Winslow Monte M.
Published: April 2023

Summary of gene sets generated from previously published analyses of the LKB1-deficient state in human lung adenocarcinoma cell lines and tumors as well as genetically engineered mouse models.
Supplementary Table S3 from An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
Authors: Murray Christopher W. , Brady Jennifer J. , Tsai Min K. , Li Chuan , Winters Ian P. , Tang Rui , Andrejka Laura , Ma Rosanna K. , Kunder Christian A. , Chu Pauline , Winslow Monte M.
Published: April 2023

Summaries of GSEA and ssGSEA analyses of human lung adenocarcinoma data sets using previously published signatures of mucinous adenocarcinoma.
Supplementary Table S1 from An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
Authors: Murray Christopher W. , Brady Jennifer J. , Tsai Min K. , Li Chuan , Winters Ian P. , Tang Rui , Andrejka Laura , Ma Rosanna K. , Kunder Christian A. , Chu Pauline , Winslow Monte M.
Published: April 2023

Summary of sgRNA characteristics and cloning strategies.
Supplementary Figures from MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
Authors: Sakthianandeswaren Anuratha , Parsons Marie J. , Mouradov Dmitri , MacKinnon Ruth N. , Catimel Bruno , Liu Sheng , Palmieri Michelle , Love Christopher , Jorissen Robert N. , Li Shan , Whitehead Lachlan , Putoczki Tracy L. , Preaudet Adele , Tsui Cary , Nowell Cameron J. , Ward Robyn L. , Hawkins Nicholas J. , Desai Jayesh , Gibbs Peter , Ernst Matthias , Street Ian , Buchert Michael , Sieber Oliver M.
Published: April 2023

Supplementary Figures 1-23 including results for fine mapping of MACROD2 deletions, xenograft assay, immunofluoresence, comet assays, western blots, PARP1 activity assays, clonogenic assays, apoptosis assays, metaphase spreads and chromosome missegregation quantification.
Supplementary Figures S1-S12 from An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
Authors: Murray Christopher W. , Brady Jennifer J. , Tsai Min K. , Li Chuan , Winters Ian P. , Tang Rui , Andrejka Laura , Ma Rosanna K. , Kunder Christian A. , Chu Pauline , Winslow Monte M.
Published: April 2023

Supplementary Figures S1-S12
Supplementary Tables S1-S4 from Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR-Amplified Gastroesophageal Adenocarcinoma
Authors: Maron Steven B. , Alpert Lindsay , Kwak Heewon A. , Lomnicki Samantha , Chase Leah , Xu David , O'Day Emily , Nagy Rebecca J. , Lanman Richard B. , Cecchi Fabiola , Hembrough Todd , Schrock Alexa , Hart John , Xiao Shu-Yuan , Setia Namrata , Catenacci Daniel V.T.
Published: April 2023

Four Supplementary Tables
Table S4 from Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer
Authors: Kitajima Shunsuke , Ivanova Elena , Guo Sujuan , Yoshida Ryohei , Campisi Marco , Sundararaman Shriram K. , Tange Shoichiro , Mitsuishi Yoichiro , Thai Tran C. , Masuda Sayuri , Piel Brandon P. , Sholl Lynette M. , Kirschmeier Paul T. , Paweletz Cloud P. , Watanabe Hideo , Yajima Mamiko , Barbie David A.
Published: April 2023

Table S4 shows primers for qRT-PCR, ChIP-qPCR, construction of sgRNA-expressing vectors and mycoplasma monitoring.
Table S2 from Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer
Authors: Kitajima Shunsuke , Ivanova Elena , Guo Sujuan , Yoshida Ryohei , Campisi Marco , Sundararaman Shriram K. , Tange Shoichiro , Mitsuishi Yoichiro , Thai Tran C. , Masuda Sayuri , Piel Brandon P. , Sholl Lynette M. , Kirschmeier Paul T. , Paweletz Cloud P. , Watanabe Hideo , Yajima Mamiko , Barbie David A.
Published: April 2023

Table S2 shows list of differentially expressed genes between KL and KP in TCGA and CCLE related with figure 1.
Table S3 from Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
Authors: Gettinger Scott , Choi Jungmin , Hastings Katherine , Truini Anna , Datar Ila , Sowell Ryan , Wurtz Anna , Dong Weilai , Cai Guoping , Melnick Mary Ann , Du Victor Y. , Schlessinger Joseph , Goldberg Sarah B. , Chiang Anne , Sanmamed Miguel F. , Melero Ignacio , Agorreta Jackeline , Montuenga Luis M. , Lifton Richard , Ferrone Soldano , Kavathas Paula , Rimm David L. , Kaech Susan M. , Schalper Kurt , Herbst Roy S. , Politi Katerina
Published: April 2023

Interferon pathway mutation and copy number alterations
Supplementary Methods from Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
Authors: Gettinger Scott , Choi Jungmin , Hastings Katherine , Truini Anna , Datar Ila , Sowell Ryan , Wurtz Anna , Dong Weilai , Cai Guoping , Melnick Mary Ann , Du Victor Y. , Schlessinger Joseph , Goldberg Sarah B. , Chiang Anne , Sanmamed Miguel F. , Melero Ignacio , Agorreta Jackeline , Montuenga Luis M. , Lifton Richard , Ferrone Soldano , Kavathas Paula , Rimm David L. , Kaech Susan M. , Schalper Kurt , Herbst Roy S. , Politi Katerina
Published: April 2023

Methods for quantitative immunofluorescence and IFN gamma treatment of PDXs
Supplementary Table S4 from Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
Authors: Aguirre Andrew J. , Nowak Jonathan A. , Camarda Nicholas D. , Moffitt Richard A. , Ghazani Arezou A. , Hazar-Rethinam Mehlika , Raghavan Srivatsan , Kim Jaegil , Brais Lauren K. , Ragon Dorisanne , Welch Marisa W. , Reilly Emma , McCabe Devin , Marini Lori , Anderka Kristin , Helvie Karla , Oliver Nelly , Babic Ana , Da Silva Annacarolina , Nadres Brandon , Van Seventer Emily E. , Shahzade Heather A. , St. Pierre Joseph P. , Burke Kelly P. , Clancy Thomas , Cleary James M. , Doyle Leona A. , Jajoo Kunal , McCleary Nadine J. , Meyerhardt Jeffrey A. , Murphy Janet E. , Ng Kimmie , Patel Anuj K. , Perez Kimberly , Rosenthal Michael H. , Rubinson Douglas A. , Ryou Marvin , Shapiro Geoffrey I. , Sicinska Ewa , Silverman Stuart G. , Nagy Rebecca J. , Lanman Richard B. , Knoerzer Deborah , Welsch Dean J. , Yurgelun Matthew B. , Fuchs Charles S. , Garraway Levi A. , Getz Gad , Hornick Jason L. , Johnson Bruce E. , Kulke Matthew H. , Mayer Robert J. , Miller Jeffrey W. , Shyn Paul B. , Tuveson David A. , Wagle Nikhil , Yeh Jen Jen , Hahn William C. , Corcoran Ryan B. , Carter Scott L. , Wolpin Brian M.
Published: April 2023

Treatment history for patients enrolled on the PancSeq protocol.
Supplementary Table S3 from Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
Authors: Aguirre Andrew J. , Nowak Jonathan A. , Camarda Nicholas D. , Moffitt Richard A. , Ghazani Arezou A. , Hazar-Rethinam Mehlika , Raghavan Srivatsan , Kim Jaegil , Brais Lauren K. , Ragon Dorisanne , Welch Marisa W. , Reilly Emma , McCabe Devin , Marini Lori , Anderka Kristin , Helvie Karla , Oliver Nelly , Babic Ana , Da Silva Annacarolina , Nadres Brandon , Van Seventer Emily E. , Shahzade Heather A. , St. Pierre Joseph P. , Burke Kelly P. , Clancy Thomas , Cleary James M. , Doyle Leona A. , Jajoo Kunal , McCleary Nadine J. , Meyerhardt Jeffrey A. , Murphy Janet E. , Ng Kimmie , Patel Anuj K. , Perez Kimberly , Rosenthal Michael H. , Rubinson Douglas A. , Ryou Marvin , Shapiro Geoffrey I. , Sicinska Ewa , Silverman Stuart G. , Nagy Rebecca J. , Lanman Richard B. , Knoerzer Deborah , Welsch Dean J. , Yurgelun Matthew B. , Fuchs Charles S. , Garraway Levi A. , Getz Gad , Hornick Jason L. , Johnson Bruce E. , Kulke Matthew H. , Mayer Robert J. , Miller Jeffrey W. , Shyn Paul B. , Tuveson David A. , Wagle Nikhil , Yeh Jen Jen , Hahn William C. , Corcoran Ryan B. , Carter Scott L. , Wolpin Brian M.
Published: April 2023

PancSeq protocol gene list for CLIA-certified somatic and germline analysis from whole exome sequencing data.
Supplementary Experimental Methods from Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
Authors: Aguirre Andrew J. , Nowak Jonathan A. , Camarda Nicholas D. , Moffitt Richard A. , Ghazani Arezou A. , Hazar-Rethinam Mehlika , Raghavan Srivatsan , Kim Jaegil , Brais Lauren K. , Ragon Dorisanne , Welch Marisa W. , Reilly Emma , McCabe Devin , Marini Lori , Anderka Kristin , Helvie Karla , Oliver Nelly , Babic Ana , Da Silva Annacarolina , Nadres Brandon , Van Seventer Emily E. , Shahzade Heather A. , St. Pierre Joseph P. , Burke Kelly P. , Clancy Thomas , Cleary James M. , Doyle Leona A. , Jajoo Kunal , McCleary Nadine J. , Meyerhardt Jeffrey A. , Murphy Janet E. , Ng Kimmie , Patel Anuj K. , Perez Kimberly , Rosenthal Michael H. , Rubinson Douglas A. , Ryou Marvin , Shapiro Geoffrey I. , Sicinska Ewa , Silverman Stuart G. , Nagy Rebecca J. , Lanman Richard B. , Knoerzer Deborah , Welsch Dean J. , Yurgelun Matthew B. , Fuchs Charles S. , Garraway Levi A. , Getz Gad , Hornick Jason L. , Johnson Bruce E. , Kulke Matthew H. , Mayer Robert J. , Miller Jeffrey W. , Shyn Paul B. , Tuveson David A. , Wagle Nikhil , Yeh Jen Jen , Hahn William C. , Corcoran Ryan B. , Carter Scott L. , Wolpin Brian M.
Published: April 2023

Supplementary Experimental Methods
MAF file for mutations from Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
Authors: Aguirre Andrew J. , Nowak Jonathan A. , Camarda Nicholas D. , Moffitt Richard A. , Ghazani Arezou A. , Hazar-Rethinam Mehlika , Raghavan Srivatsan , Kim Jaegil , Brais Lauren K. , Ragon Dorisanne , Welch Marisa W. , Reilly Emma , McCabe Devin , Marini Lori , Anderka Kristin , Helvie Karla , Oliver Nelly , Babic Ana , Da Silva Annacarolina , Nadres Brandon , Van Seventer Emily E. , Shahzade Heather A. , St. Pierre Joseph P. , Burke Kelly P. , Clancy Thomas , Cleary James M. , Doyle Leona A. , Jajoo Kunal , McCleary Nadine J. , Meyerhardt Jeffrey A. , Murphy Janet E. , Ng Kimmie , Patel Anuj K. , Perez Kimberly , Rosenthal Michael H. , Rubinson Douglas A. , Ryou Marvin , Shapiro Geoffrey I. , Sicinska Ewa , Silverman Stuart G. , Nagy Rebecca J. , Lanman Richard B. , Knoerzer Deborah , Welsch Dean J. , Yurgelun Matthew B. , Fuchs Charles S. , Garraway Levi A. , Getz Gad , Hornick Jason L. , Johnson Bruce E. , Kulke Matthew H. , Mayer Robert J. , Miller Jeffrey W. , Shyn Paul B. , Tuveson David A. , Wagle Nikhil , Yeh Jen Jen , Hahn William C. , Corcoran Ryan B. , Carter Scott L. , Wolpin Brian M.
Published: April 2023

MAF file for mutations identified in the cohort
Table S4 from Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma
Authors: Rajbhandari Presha , Lopez Gonzalo , Capdevila Claudia , Salvatori Beatrice , Yu Jiyang , Rodriguez-Barrueco Ruth , Martinez Daniel , Yarmarkovich Mark , Weichert-Leahey Nina , Abraham Brian J. , Alvarez Mariano J. , Iyer Archana , Harenza Jo Lynne , Oldridge Derek , De Preter Katleen , Koster Jan , Asgharzadeh Shahab , Seeger Robert C. , Wei Jun S. , Khan Javed , Vandesompele Jo , Mestdagh Pieter , Versteeg Rogier , Look A. Thomas , Young Richard A. , Iavarone Antonio , Lasorella Anna , Silva Jose M. , Maris John M. , Califano Andrea
Published: April 2023

Master Regulator Analysis results from msVIPER
Supplementary Table S11 and 15 from Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition
Authors: Ennishi Daisuke , Takata Katsuyoshi , Béguelin Wendy , Duns Gerben , Mottok Anja , Farinha Pedro , Bashashati Ali , Saberi Saeed , Boyle Merrill , Meissner Barbara , Ben-Neriah Susana , Woolcock Bruce W. , Telenius Adèle , Lai Daniel , Teater Matt , Kridel Robert , Savage Kerry J. , Sehn Laurie H. , Morin Ryan D. , Marra Marco A. , Shah Sohrab P. , Connors Joseph M. , Gascoyne Randy D. , Scott David W. , Melnick Ari M. , Steidl Christian
Published: April 2023

IHC antibodies and cell line information
Supplementary Materials and Methods from In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2–CDK4/6 Targeting and mTOR–S6 Resistance Mechanisms
Authors: Teh Jessica L.F. , Cheng Phil F. , Purwin Timothy J. , Nikbakht Neda , Patel Prem , Chervoneva Inna , Ertel Adam , Fortina Paolo M. , Kleiber Ines , HooKim Kim , Davies Michael A. , Kwong Lawrence N. , Levesque Mitch P. , Dummer Reinhard , Aplin Andrew E.
Published: April 2023

Materials and Methods
Supplementary Methods from Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers
Authors: Drilon Alexander , Somwar Romel , Mangatt Biju P. , Edgren Henrik , Desmeules Patrice , Ruusulehto Anja , Smith Roger S. , Delasos Lukas , Vojnic Morana , Plodkowski Andrew J. , Sabari Joshua , Ng Kenneth , Montecalvo Joseph , Chang Jason , Tai Huichun , Lockwood William W. , Martinez Victor , Riely Gregory J. , Rudin Charles M. , Kris Mark G. , Arcila Maria E. , Matheny Christopher , Benayed Ryma , Rekhtman Natasha , Ladanyi Marc , Ganji Gopinath
Published: April 2023

Supplementary Methods
Figure S2 from Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers
Authors: Seguin Laetitia , Camargo Maria F. , Wettersten Hiromi I. , Kato Shumei , Desgrosellier Jay S. , von Schalscha Tami , Elliott Kathryn C. , Cosset Erika , Lesperance Jacqueline , Weis Sara M. , Cheresh David A.
Published: April 2023

Supplement to Figure 2
Tables S1-5 from A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2–Positive Metastatic Breast Cancer
Authors: Lok Sheau W. , Whittle James R. , Vaillant François , Teh Charis E. , Lo Louisa L. , Policheni Antonia N. , Bergin Alice R.T. , Desai Jayesh , Ftouni Sarah , Gandolfo Luke C. , Liew Danny , Liu He K. , Mann G. Bruce , Moodie Kate , Murugasu Anand , Pal Bhupinder , Roberts Andrew W. , Rosenthal Mark A. , Shackleton Kylie , Silva Maria João , Siow Zhen R. , Smyth Gordon K. , Taylor Leanne , Travers Avraham , Yeo Belinda , Yeung Miriam M. , Bujak Andjelija Zivanovic , Dawson Sarah-Jane , Gray Daniel H.D. , Visvader Jane E. , Lindeman Geoffrey J.
Published: April 2023

Supplementary Tables S1-5
Supplementary Data S1 from Disabled Homolog 2 Controls Prometastatic Activity of Tumor-Associated Macrophages
Authors: Marigo Ilaria , Trovato Rosalinda , Hofer Francesca , Ingangi Vincenzo , De Sanctis Francesco , Ugel Stefano , Canè Stefania , Simonelli Anna , Lamolinara Alessia , Iezzi Manuela , Fassan Matteo , Rugge Massimo , Boschi Federico , Borile Giulia , Eisenhaure Thomas , Sarkizova Siranush , Lieb David , Hacohen Nir , Azzolin Luca , Piccolo Stefano , Lawlor Rita , Scarpa Aldo , Carbognin Luisa , Bria Emilio , Bicciato Silvio , Murray Peter J. , Bronte Vincenzo
Published: April 2023

Marker genes for each cell type identified in tumor-infiltrating myeloid cells.Related to Fig.1A
CD-20-0142R1_Supplementary_Tables.docx from BI-3406, a Potent and Selective SOS1–KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Authors: Hofmann Marco H. , Gmachl Michael , Ramharter Juergen , Savarese Fabio , Gerlach Daniel , Marszalek Joseph R. , Sanderson Michael P. , Kessler Dirk , Trapani Francesca , Arnhof Heribert , Rumpel Klaus , Botesteanu Dana-Adriana , Ettmayer Peter , Gerstberger Thomas , Kofink Christiane , Wunberg Tobias , Zoephel Andreas , Fu Szu-Chin , Teh Jessica L. , Böttcher Jark , Pototschnig Nikolai , Schachinger Franziska , Schipany Katharina , Lieb Simone , Vellano Christopher P. , O'Connell Jonathan C. , Mendes Rachel L. , Moll Jurgen , Petronczki Mark , Heffernan Timothy P. , Pearson Mark , McConnell Darryl B. , Kraut Norbert
Published: April 2023

Supplementary Data, Table S1, S3, S6, S8, S10-S13
CD-20-0142R1_Supplementary_Table_S5.xlsx from BI-3406, a Potent and Selective SOS1–KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Authors: Hofmann Marco H. , Gmachl Michael , Ramharter Juergen , Savarese Fabio , Gerlach Daniel , Marszalek Joseph R. , Sanderson Michael P. , Kessler Dirk , Trapani Francesca , Arnhof Heribert , Rumpel Klaus , Botesteanu Dana-Adriana , Ettmayer Peter , Gerstberger Thomas , Kofink Christiane , Wunberg Tobias , Zoephel Andreas , Fu Szu-Chin , Teh Jessica L. , Böttcher Jark , Pototschnig Nikolai , Schachinger Franziska , Schipany Katharina , Lieb Simone , Vellano Christopher P. , O'Connell Jonathan C. , Mendes Rachel L. , Moll Jurgen , Petronczki Mark , Heffernan Timothy P. , Pearson Mark , McConnell Darryl B. , Kraut Norbert
Published: April 2023

Table S5
CD-20-0142R1_Supplementary_Table_S4.xlsx from BI-3406, a Potent and Selective SOS1–KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Authors: Hofmann Marco H. , Gmachl Michael , Ramharter Juergen , Savarese Fabio , Gerlach Daniel , Marszalek Joseph R. , Sanderson Michael P. , Kessler Dirk , Trapani Francesca , Arnhof Heribert , Rumpel Klaus , Botesteanu Dana-Adriana , Ettmayer Peter , Gerstberger Thomas , Kofink Christiane , Wunberg Tobias , Zoephel Andreas , Fu Szu-Chin , Teh Jessica L. , Böttcher Jark , Pototschnig Nikolai , Schachinger Franziska , Schipany Katharina , Lieb Simone , Vellano Christopher P. , O'Connell Jonathan C. , Mendes Rachel L. , Moll Jurgen , Petronczki Mark , Heffernan Timothy P. , Pearson Mark , McConnell Darryl B. , Kraut Norbert
Published: April 2023

Table S4
Supplementary Table S2 from An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants
Authors: Zafra Maria Paz , Parsons Marie J. , Kim Jangkyung , Alonso-Curbelo Direna , Goswami Sukanya , Schatoff Emma M. , Han Teng , Katti Alyna , Fernandez Maria Teresa Calvo , Wilkinson John E. , Piskounova Elena , Dow Lukas E.
Published: April 2023

ESC clone mutations detected from WES
Supplementary Data from Acalabrutinib plus Obinutuzumab in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia
Authors: Woyach Jennifer A. , Blachly James S. , Rogers Kerry A. , Bhat Seema A. , Jianfar Mojgan , Lozanski Gerard , Weiss David M. , Andersen Barbara L. , Gulrajani Michael , Frigault Melanie M. , Hamdy Ahmed , Izumi Raquel , Munugalavadla Veerendra , Quah Cheng , Wang Min-Hui , Byrd John C.
Published: April 2023

Figure S1 shows immunoglobulin A, B, and M levels in treated patients over time Figure S2 shows investigator-assessed progression-free survival by CLL-IPI score and presence or absence of complex karyotype
Supplementary Table 2 from EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress
Authors: León Theresa E. , Rapoz-D'Silva Tanya , Bertoli Cosetta , Rahman Sunniyat , Magnussen Michael , Philip Brian , Farah Nadine , Richardson Simon E. , Ahrabi Sara , Guerra-Assunção José Afonso , Gupta Rajeev , Nacheva Elisabeth P. , Henderson Stephen , Herrero Javier , Linch David C. , de Bruin Robertus A.M. , Mansour Marc R.
Published: April 2023

Supplementary Table 2: Cell viability data from the small-molecule drug screening in EZH2-WT and EZH2-KO1 cells (related to Fig. 1)
Supplemental Table 1 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Authors: Wander Seth A. , Cohen Ofir , Gong Xueqian , Johnson Gabriela N. , Buendia-Buendia Jorge E. , Lloyd Maxwell R. , Kim Dewey , Luo Flora , Mao Pingping , Helvie Karla , Kowalski Kailey J. , Nayar Utthara , Waks Adrienne G. , Parsons Stephen H. , Martinez Ricardo , Litchfield Lacey M. , Ye Xiang S. , Yu Chunping , Jansen Valerie M. , Stille John R. , Smith Patricia S. , Oakley Gerard J. , Chu Quincy S. , Batist Gerald , Hughes Melissa E. , Kremer Jill D. , Garraway Levi A. , Winer Eric P. , Tolaney Sara M. , Lin Nancy U. , Buchanan Sean G. , Wagle Nikhil
Published: April 2023

Supplemental Table 1
Supplemental Figure 9 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Authors: Wander Seth A. , Cohen Ofir , Gong Xueqian , Johnson Gabriela N. , Buendia-Buendia Jorge E. , Lloyd Maxwell R. , Kim Dewey , Luo Flora , Mao Pingping , Helvie Karla , Kowalski Kailey J. , Nayar Utthara , Waks Adrienne G. , Parsons Stephen H. , Martinez Ricardo , Litchfield Lacey M. , Ye Xiang S. , Yu Chunping , Jansen Valerie M. , Stille John R. , Smith Patricia S. , Oakley Gerard J. , Chu Quincy S. , Batist Gerald , Hughes Melissa E. , Kremer Jill D. , Garraway Levi A. , Winer Eric P. , Tolaney Sara M. , Lin Nancy U. , Buchanan Sean G. , Wagle Nikhil
Published: April 2023

Figure S9
Supplemental Figure 4 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Authors: Wander Seth A. , Cohen Ofir , Gong Xueqian , Johnson Gabriela N. , Buendia-Buendia Jorge E. , Lloyd Maxwell R. , Kim Dewey , Luo Flora , Mao Pingping , Helvie Karla , Kowalski Kailey J. , Nayar Utthara , Waks Adrienne G. , Parsons Stephen H. , Martinez Ricardo , Litchfield Lacey M. , Ye Xiang S. , Yu Chunping , Jansen Valerie M. , Stille John R. , Smith Patricia S. , Oakley Gerard J. , Chu Quincy S. , Batist Gerald , Hughes Melissa E. , Kremer Jill D. , Garraway Levi A. , Winer Eric P. , Tolaney Sara M. , Lin Nancy U. , Buchanan Sean G. , Wagle Nikhil
Published: April 2023

Figure S4
Supplemental Figure 3 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Authors: Wander Seth A. , Cohen Ofir , Gong Xueqian , Johnson Gabriela N. , Buendia-Buendia Jorge E. , Lloyd Maxwell R. , Kim Dewey , Luo Flora , Mao Pingping , Helvie Karla , Kowalski Kailey J. , Nayar Utthara , Waks Adrienne G. , Parsons Stephen H. , Martinez Ricardo , Litchfield Lacey M. , Ye Xiang S. , Yu Chunping , Jansen Valerie M. , Stille John R. , Smith Patricia S. , Oakley Gerard J. , Chu Quincy S. , Batist Gerald , Hughes Melissa E. , Kremer Jill D. , Garraway Levi A. , Winer Eric P. , Tolaney Sara M. , Lin Nancy U. , Buchanan Sean G. , Wagle Nikhil
Published: April 2023

Figure S3
Supplementary Table S4 from Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis
Authors: Kato Shinichiro , Weng Qing Yu , Insco Megan L. , Chen Kevin Y. , Muralidhar Sathya , Pozniak Joanna , Diaz Joey Mark S. , Drier Yotam , Nguyen Nhu , Lo Jennifer A. , van Rooijen Ellen , Kemeny Lajos V. , Zhan Yao , Feng Yang , Silkworth Whitney , Powell C. Thomas , Liau Brian B. , Xiong Yan , Jin Jian , Newton-Bishop Julia , Zon Leonard I. , Bernstein Bradley E. , Fisher David E.
Published: April 2023

Pathways associated with G9a copy number in the Leeds melanoma cohort
Supplementary Figures from Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells
Authors: Nagashima Hiroaki , Lee Christine K. , Tateishi Kensuke , Higuchi Fumi , Subramanian Megha , Rafferty Seamus , Melamed Lisa , Miller Julie J. , Wakimoto Hiroaki , Cahill Daniel P.
Published: April 2023

Supplementary Figures S1-S8 with Legends.
Tables S1,2,3 from Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin
Authors: Espinet Elisa , Gu Zuguang , Imbusch Charles D. , Giese Nathalia A. , Büscher Magdalena , Safavi Mariam , Weisenburger Silke , Klein Corinna , Vogel Vanessa , Falcone Mattia , Insua-Rodríguez Jacob , Reitberger Manuel , Thiel Vera , Kossi Steffi O. , Muckenhuber Alexander , Sarai Karnjit , Lee Alex Y.L. , Backx Elyne , Zarei Soheila , Gaida Matthias M. , Rodríguez-Paredes Manuel , Donato Elisa , Yen Hsi-Yu , Eils Roland , Schlesner Matthias , Pfarr Nicole , Hackert Thilo , Plass Christoph , Brors Benedikt , Steiger Katja , Weichenhan Dieter , Arda H. Efsun , Rooman Ilse , Kopp Janel L. , Strobel Oliver , Weichert Wilko , Sprick Martin R. , Trumpp Andreas
Published: April 2023

Patient characteristics and sequencing QC results
Supplementary Figures S1-S15 from Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin
Authors: Espinet Elisa , Gu Zuguang , Imbusch Charles D. , Giese Nathalia A. , Büscher Magdalena , Safavi Mariam , Weisenburger Silke , Klein Corinna , Vogel Vanessa , Falcone Mattia , Insua-Rodríguez Jacob , Reitberger Manuel , Thiel Vera , Kossi Steffi O. , Muckenhuber Alexander , Sarai Karnjit , Lee Alex Y.L. , Backx Elyne , Zarei Soheila , Gaida Matthias M. , Rodríguez-Paredes Manuel , Donato Elisa , Yen Hsi-Yu , Eils Roland , Schlesner Matthias , Pfarr Nicole , Hackert Thilo , Plass Christoph , Brors Benedikt , Steiger Katja , Weichenhan Dieter , Arda H. Efsun , Rooman Ilse , Kopp Janel L. , Strobel Oliver , Weichert Wilko , Sprick Martin R. , Trumpp Andreas
Published: April 2023

Supplementary Figures S1 to S15
Supplementary Table 1 from Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition
Authors: Cai Sheng F. , Chu S. Haihua , Goldberg Aaron D. , Parvin Salma , Koche Richard P. , Glass Jacob L. , Stein Eytan M. , Tallman Martin S. , Sen Filiz , Famulare Christopher A. , Cusan Monica , Huang Chun-Hao , Chen Chun-Wei , Zou Lihua , Cordner Keith B. , DelGaudio Nicole L. , Durani Vidushi , Kini Mitali , Rex Madison , Tian Helen S. , Zuber Johannes , Baslan Timour , Lowe Scott W. , Rienhoff Hugh Y. , Letai Anthony , Levine Ross L. , Armstrong Scott A.
Published: April 2023

shRNA screen hits
Supplementary Data from Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer
Authors: Pinato David J. , Zambelli Alberto , Aguilar-Company Juan , Bower Mark , Sng Christopher C.T. , Salazar Ramon , Bertuzzi Alexia , Brunet Joan , Mesia Ricard , Seguí Elia , Biello Federica , Generali Daniele , Grisanti Salvatore , Rizzo Gianpiero , Libertini Michela , Maconi Antonio , Harbeck Nadia , Vincenzi Bruno , Bertulli Rossella , Ottaviani Diego , Carbó Anna , Bruna Riccardo , Benafif Sarah , Marrari Andrea , Wuerstlein Rachel , Carmona-Garcia M. Carmen , Chopra Neha , Tondini Carlo , Mirallas Oriol , Tovazzi Valeria , Betti Marta , Provenzano Salvatore , Fotia Vittoria , Cruz Claudia Andrea , Dalla Pria Alessia , D'Avanzo Francesca , Evans Joanne S. , Saoudi-Gonzalez Nadia , Felip Eudald , Galazi Myria , Garcia-Fructuoso Isabel , Lee Alvin J.X. , Newsom-Davis Thomas , Patriarca Andrea , García-Illescas David , Reyes Roxana , Dileo Palma , Sharkey Rachel , Wong Yien Ning Sophia , Ferrante Daniela , Marco-Hernández Javier , Sureda Anna , Maluquer Clara , Ruiz-Camps Isabel , Gaidano Gianluca , Rimassa Lorenza , Chiudinelli Lorenzo , Izuzquiza Macarena , Cabirta Alba , Franchi Michela , Santoro Armando , Prat Aleix , Tabernero Josep , Gennari Alessandra , Avanzi Gian Carlo , Bellan Mattia , Castello Luigi Mario , Martinez Maria , Mollà Meritxell , Pirisi Mario , Scotti Lorenza , Swallow Judith
Published: April 2023

Supplementary Tables and Figures
Supplementary Data from The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG
Authors: Ye Haobin , Minhajuddin Mohammad , Krug Anna , Pei Shanshan , Chou Chih-Hsing , Culp-Hill Rachel , Ponder Jessica , De Bloois Erik , Schniedewind Björn , Amaya Maria L. , Inguva Anagha , Stevens Brett M. , Pollyea Daniel A. , Christians Uwe , Grimes H. Leighton , D'Alessandro Angelo , Jordan Craig T.
Published: April 2023

Supplementary figures and information
Supplementary Data from The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG
Authors: Ye Haobin , Minhajuddin Mohammad , Krug Anna , Pei Shanshan , Chou Chih-Hsing , Culp-Hill Rachel , Ponder Jessica , De Bloois Erik , Schniedewind Björn , Amaya Maria L. , Inguva Anagha , Stevens Brett M. , Pollyea Daniel A. , Christians Uwe , Grimes H. Leighton , D'Alessandro Angelo , Jordan Craig T.
Published: April 2023

Supplemental Table 1
Table S7 from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
Authors: Hong Xin , Roh Whijae , Sullivan Ryan J. , Wong Keith H.K. , Wittner Ben S. , Guo Hongshan , Dubash Taronish D. , Sade-Feldman Moshe , Wesley Benjamin , Horwitz Elad , Boland Genevieve M. , Marvin Dieuwke L. , Bonesteel Todd , Lu Chenyue , Aguet François , Burr Risa , Freeman Samuel S. , Parida Laxmi , Calhoun Katherine , Jewett Michelle K. , Nieman Linda T. , Hacohen Nir , Näär Anders M. , Ting David T. , Toner Mehmet , Stott Shannon L. , Getz Gad , Maheswaran Shyamala , Haber Daniel A.
Published: April 2023

Table S7
Table S4 from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
Authors: Hong Xin , Roh Whijae , Sullivan Ryan J. , Wong Keith H.K. , Wittner Ben S. , Guo Hongshan , Dubash Taronish D. , Sade-Feldman Moshe , Wesley Benjamin , Horwitz Elad , Boland Genevieve M. , Marvin Dieuwke L. , Bonesteel Todd , Lu Chenyue , Aguet François , Burr Risa , Freeman Samuel S. , Parida Laxmi , Calhoun Katherine , Jewett Michelle K. , Nieman Linda T. , Hacohen Nir , Näär Anders M. , Ting David T. , Toner Mehmet , Stott Shannon L. , Getz Gad , Maheswaran Shyamala , Haber Daniel A.
Published: April 2023

Table S4
Table S3 from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
Authors: Hong Xin , Roh Whijae , Sullivan Ryan J. , Wong Keith H.K. , Wittner Ben S. , Guo Hongshan , Dubash Taronish D. , Sade-Feldman Moshe , Wesley Benjamin , Horwitz Elad , Boland Genevieve M. , Marvin Dieuwke L. , Bonesteel Todd , Lu Chenyue , Aguet François , Burr Risa , Freeman Samuel S. , Parida Laxmi , Calhoun Katherine , Jewett Michelle K. , Nieman Linda T. , Hacohen Nir , Näär Anders M. , Ting David T. , Toner Mehmet , Stott Shannon L. , Getz Gad , Maheswaran Shyamala , Haber Daniel A.
Published: April 2023

Table S3
Supplementary Table from Timed Ang2-Targeted Therapy Identifies the Angiopoietin–Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis
Authors: Gengenbacher Nicolas , Singhal Mahak , Mogler Carolin , Hai Ling , Milde Laura , Pari Ashik Ahmed Abdul , Besemfelder Eva , Fricke Claudine , Baumann Daniel , Gehrs Stephanie , Utikal Jochen , Felcht Moritz , Hu Junhao , Schlesner Matthias , Offringa Rienk , Chintharlapalli Sudhakar R. , Augustin Hellmut G.
Published: April 2023

Table S1
Supplementary Table S16 from Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Authors: Elyada Ela , Bolisetty Mohan , Laise Pasquale , Flynn William F. , Courtois Elise T. , Burkhart Richard A. , Teinor Jonathan A. , Belleau Pascal , Biffi Giulia , Lucito Matthew S. , Sivajothi Santhosh , Armstrong Todd D. , Engle Dannielle D. , Yu Kenneth H. , Hao Yuan , Wolfgang Christopher L. , Park Youngkyu , Preall Jonathan , Jaffee Elizabeth M. , Califano Andrea , Robson Paul , Tuveson David A.
Published: April 2023

Supplementary Table S16 shows protein activity of transcription factors in human CAFs, as analyzed by VIPER
Supplementary Table S13 from Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Authors: Elyada Ela , Bolisetty Mohan , Laise Pasquale , Flynn William F. , Courtois Elise T. , Burkhart Richard A. , Teinor Jonathan A. , Belleau Pascal , Biffi Giulia , Lucito Matthew S. , Sivajothi Santhosh , Armstrong Todd D. , Engle Dannielle D. , Yu Kenneth H. , Hao Yuan , Wolfgang Christopher L. , Park Youngkyu , Preall Jonathan , Jaffee Elizabeth M. , Califano Andrea , Robson Paul , Tuveson David A.
Published: April 2023

Supplementary Table S13 shows marker genes of the different human fibroblasts
Supplementary Figures from TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
Authors: Cocco Emiliano , Lee Ji Eun , Kannan Srinivasaraghavan , Schram Alison M. , Won Helen H. , Shifman Sophie , Kulick Amanda , Baldino Laura , Toska Eneda , Arruabarrena-Aristorena Amaia , Kittane Srushti , Wu Fan , Cai Yanyan , Arena Sabrina , Mussolin Benedetta , Kannan Ram , Vasan Neil , Gorelick Alexander N. , Berger Michael F. , Novoplansky Ofra , Jagadeeshan Sankar , Liao Yi , Rix Uwe , Misale Sandra , Taylor Barry S. , Bardelli Alberto , Hechtman Jaclyn F. , Hyman David M. , Elkabets Moshe , de Stanchina Elisa , Verma Chandra S. , Ventura Andrea , Drilon Alexander , Scaltriti Maurizio
Published: April 2023

Supplementary Figures
Supplementary Tables 1 to 11 from Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene–Driven Myeloid Leukemia
Authors: Lopez Cécile K. , Noguera Esteve , Stavropoulou Vaia , Robert Elie , Aid Zakia , Ballerini Paola , Bilhou-Nabera Chrystèle , Lapillonne Hélène , Boudia Fabien , Thirant Cécile , Fagnan Alexandre , Arcangeli Marie-Laure , Kinston Sarah J. , Diop M'Boyba , Job Bastien , Lecluse Yann , Brunet Erika , Babin Loélia , Villeval Jean Luc , Delabesse Eric , Peters Antoine H.F.M. , Vainchenker William , Gaudry Muriel , Masetti Riccardo , Locatelli Franco , Malinge Sébastien , Nerlov Claus , Droin Nathalie , Lobry Camille , Godin Isabelle , Bernard Olivier A. , Göttgens Berthold , Petit Arnaud , Pflumio Françoise , Schwaller Juerg , Mercher Thomas
Published: April 2023

Supplementary Tables 1 to 11
Figure S2 from Antitumor T-cell Homeostatic Activation Is Uncoupled from Homeostatic Inhibition by Checkpoint Blockade
Authors: Marshall Netonia , Hutchinson Keino , Marron Thomas U. , Aleynick Mark , Hammerich Linda , Upadhyay Ranjan , Svensson-Arvelund Judit , Brown Brian D. , Merad Miriam , Brody Joshua D.
Published: April 2023

Transfer induces homeostatic inhibition
Figure S1 from Antitumor T-cell Homeostatic Activation Is Uncoupled from Homeostatic Inhibition by Checkpoint Blockade
Authors: Marshall Netonia , Hutchinson Keino , Marron Thomas U. , Aleynick Mark , Hammerich Linda , Upadhyay Ranjan , Svensson-Arvelund Judit , Brown Brian D. , Merad Miriam , Brody Joshua D.
Published: April 2023

Transfer does not induce homeostatic inhibition on CD4+ T-cells
Supplementary Figures and Legends from Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene–Driven Myeloid Leukemia
Authors: Lopez Cécile K. , Noguera Esteve , Stavropoulou Vaia , Robert Elie , Aid Zakia , Ballerini Paola , Bilhou-Nabera Chrystèle , Lapillonne Hélène , Boudia Fabien , Thirant Cécile , Fagnan Alexandre , Arcangeli Marie-Laure , Kinston Sarah J. , Diop M'Boyba , Job Bastien , Lecluse Yann , Brunet Erika , Babin Loélia , Villeval Jean Luc , Delabesse Eric , Peters Antoine H.F.M. , Vainchenker William , Gaudry Muriel , Masetti Riccardo , Locatelli Franco , Malinge Sébastien , Nerlov Claus , Droin Nathalie , Lobry Camille , Godin Isabelle , Bernard Olivier A. , Göttgens Berthold , Petit Arnaud , Pflumio Françoise , Schwaller Juerg , Mercher Thomas
Published: April 2023

Supplementary Figures and Legends
Supplementary Figure S2 from First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study
Authors: Khot Amit , Brajanovski Natalie , Cameron Donald P. , Hein Nadine , Maclachlan Kylee H. , Sanij Elaine , Lim John , Soong John , Link Emma , Blombery Piers , Thompson Ella R. , Fellowes Andrew , Sheppard Karen E. , McArthur Grant A. , Pearson Richard B. , Hannan Ross D. , Poortinga Gretchen , Harrison Simon J.
Published: April 2023

Pharmacokinetics analysis of CX-5461 in patients with advanced hematological disease
Table S1 from Phenotypic Mapping of Pathologic Cross-Talk between Glioblastoma and Innate Immune Cells by Synthetic Genetic Tracing
Authors: Schmitt Matthias Jürgen , Company Carlos , Dramaretska Yuliia , Barozzi Iros , Göhrig Andreas , Kertalli Sonia , Großmann Melanie , Naumann Heike , Sanchez-Bailon Maria Pilar , Hulsman Danielle , Glass Rainer , Squatrito Massimo , Serresi Michela , Gargiulo Gaetano
Published: April 2023

Supplementary Table S1. GBM-sLCR features
Supplementary Table S3 from Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas
Authors: Zheng Tuyu , Ghasemi David R. , Okonechnikov Konstantin , Korshunov Andrey , Sill Martin , Maass Kendra K. , Benites Goncalves da Silva Patricia , Ryzhova Marina , Gojo Johannes , Stichel Damian , Arabzade Amir , Kupp Robert , Benzel Julia , Taya Shinichiro , Adachi Toma , Shiraishi Ryo , Gerber Nicolas U. , Sturm Dominik , Ecker Jonas , Sievers Philipp , Selt Florian , Chapman Rebecca , Haberler Christine , Figarella-Branger Dominique , Reifenberger Guido , Fleischhack Gudrun , Rutkowski Stefan , Donson Andrew M. , Ramaswamy Vijay , Capper David , Ellison David W. , Herold-Mende Christel C. , Schüller Ulrich , Brandner Sebastian , Driever Pablo Hernáiz , Kros Johan M. , Snuderl Matija , Milde Till , Grundy Richard G. , Hoshino Mikio , Mack Stephen C. , Gilbertson Richard J. , Jones David T.W. , Kool Marcel , von Deimling Andreas , Pfister Stefan M. , Sahm Felix , Kawauchi Daisuke , Pajtler Kristian W.
Published: April 2023

Suppl. Table S3 - Differentially expressed genes of ST-EPN-RELA and cluster 2 - 4
Supplementary Table S1 from Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas
Authors: Zheng Tuyu , Ghasemi David R. , Okonechnikov Konstantin , Korshunov Andrey , Sill Martin , Maass Kendra K. , Benites Goncalves da Silva Patricia , Ryzhova Marina , Gojo Johannes , Stichel Damian , Arabzade Amir , Kupp Robert , Benzel Julia , Taya Shinichiro , Adachi Toma , Shiraishi Ryo , Gerber Nicolas U. , Sturm Dominik , Ecker Jonas , Sievers Philipp , Selt Florian , Chapman Rebecca , Haberler Christine , Figarella-Branger Dominique , Reifenberger Guido , Fleischhack Gudrun , Rutkowski Stefan , Donson Andrew M. , Ramaswamy Vijay , Capper David , Ellison David W. , Herold-Mende Christel C. , Schüller Ulrich , Brandner Sebastian , Driever Pablo Hernáiz , Kros Johan M. , Snuderl Matija , Milde Till , Grundy Richard G. , Hoshino Mikio , Mack Stephen C. , Gilbertson Richard J. , Jones David T.W. , Kool Marcel , von Deimling Andreas , Pfister Stefan M. , Sahm Felix , Kawauchi Daisuke , Pajtler Kristian W.
Published: April 2023

Suppl. Table S1 - A summary of the human cohort used for DNA methylation-profiling_DRG3003
Supplementary Fig. S5 from Impact of HER2 Heterogeneity on Treatment Response of Early-Stage HER2-Positive Breast Cancer: Phase II Neoadjuvant Clinical Trial of T-DM1 Combined with Pertuzumab
Authors: Filho Otto Metzger , Viale Giuseppe , Stein Shayna , Trippa Lorenzo , Yardley Denise A. , Mayer Ingrid A. , Abramson Vandana G. , Arteaga Carlos L. , Spring Laura M. , Waks Adrienne G. , Wrabel Eileen , DeMeo Michelle K. , Bardia Aditya , Dell'Orto Patrizia , Russo Leila , King Tari A. , Polyak Kornelia , Michor Franziska , Winer Eric P. , Krop Ian E.
Published: April 2023

Predicting pathological complete response (pCR) from single cell HER2 FISH and clinical data. A, Receiver operating characteristic (ROC) curves for the prediction models using the frequency of HER2 unamplified cells to predict pathological response. Blue: the model results using all patients, green: model results for the subet of hormone receptor positive cases, and orange: model results for the subset of hormone receptor negative cases. AUC is the area under the corresponding ROC curve. B, ROC curves for the logistic regression models 1 (blue), 2 (orange), 3 (green), 4 (red), 5 (purple), 6 (brown), 7 (pink) to predict pathological response. AUC is the area under the corresponding ROC curve.