bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINICAL AND HEMATOLOGICAL EFFECTS OF HYDROXYUREA THERAPY IN MANAGEMENT OF SICKLE CELL ANEMIA
Authors: Shukla Dr. Rajesh , Gajera Dr. Mehul
Published: July 2019

Background: The most predominant form of haemoglobinopathy worldwide is sickle cell disease. The greatest burden of the disease lies in sub-Saharan Africa and Asia5.

Objective: To evaluate the effectiveness of HU therapy in sickle cell disease as measured by decrease in crises rate, hospital admissions, days of hospitalization and number of blood transfusions.

Methods: the study was conducted on 79 children of 1-16 year age. Out of which in only 75 patients Hydroxyurea therapy was started as they were found to be eligible. 16% of the patients responded to 15 mg/kg/ day of HU, 50.66% responded to 20 mg/kg/ day, 29.33% to 25 mg/kg/ day and only 4% needed a dose escalation to 30 mg/kg/ day for the response.

Results: Our study showed a significant reduction in the VOC rate from 243 episodes to 46 episodes (p value <0.001), the number of ACS reduced from 37 episodes to 5 episodes (p value <0.001), also there is a significant decline in the rates of hemolytic crises from 63 episodes to 10 episodes per year, Significant increase in the HbF levels from 15.87±5.50% to 21.77.±4.06% (p value <0.001). There was a definite and significant reduction in the number of hospitalization days from 7.76±4.76 to 3.79±2.29 days and in the number of admissions per year dropped significantly from 4.80 ± 1.41 to 1.42± 0.61 per year.

Conclusion: Hydroxyurea reduced the frequency of painful crises and diminished the number of hospitalization, transfusion, and episodes of acute chest syndrome17.

Keywords: Haemoglobin (Hb), Hydroxyurea (HU), Mean Corpuscular Volume (MCV), Pletelet Counts, Sickle Cell Disease (SCD), White Blood Cells (WBC).
Simulation of Object Movement Analysis
Authors: Sharma Ambika , Mamta Mrs.
Published: July 2019

There are many approaches for motion detection in a continuous video stream. All of them are based on comparing of the current video frame with one from the previous frames or with something that we'll call background. This research project is carried out to determine some of the basic simulation of object motion analysis algorithm that had been founded or developed or even researched and Supports the following types of video sources: AVI files, local capture device .This thesis report would bring a presentation of these algorithms for researchers to get a basic idea of performing an algorithm for simulation of object motion Analysis. One of the most common approaches is to compare the current frame with the previous one. It's useful in video compression when you need to estimate changes and to write only the changes, not the whole frame. But it is not the best one for motion detection applications. If the object is moving smoothly we'll receive small changes from frame to frame. So, it's impossible to get the whole moving object. Things become worse, when the object is moving so slowly, when the algorithms will not give any result at all. I used an image processing library for simplicity, it's not a video processing library. Besides, the library allows me to research different areas more quickly, than to write optimized solutions. I use LDA (Linear Discriminant Analysis) Algorithm for face and object detection. LDA maximizing the component axes for class separation. LDA tries to find projection axes, such as classes are best separated. LDA can be used not only for classification, but also for dimensionality reduction.
Assessment of the Effect of Biochar and Leucaena Leucocephala on the Growth and Yield of Maize (Zea mays)
Authors: Brempong Lydia Numafo , Dawoe Evans , Ibrahim Muhammad
Published: July 2019

Studies have been conducted to assess the effect of Leucaena leucocephala biomass on various crops but none has compared the effect of L. leucocephala biomass and its biochar on crops. The study therefore aimed at assessing the effect biochar and L. leucocephala have on the growth and yield of maize. It was hypothesized that biochar would have a better effect on the growth of maize than Leucaena biomass. There were six (6) treatments comprising T1= L. leucocephala, T2=Biochar, T3=Biochar + Fertilizer, T4= L. leucocephala + Fertilizer, T5=Fertilizer and T6=Control. The biochar was prepared from L. leucocephala cuttings whiles the leaves of L. leucocephala were used as its biomass. The fertilizer used was ammonia. Besides the control, all treatments were designed to supply 160kgN/ha. The result of the study showed that Leucaena biomass and biochar had same effect on the yield but Leucaena biomass had a better effect on the growth of maize than biochar. Nitrogen content of the soil increased significantly in response to both Leucaena biomass and biochar treatments. This study concludes that L. leucocephala biomass (under short term) will produce the same effect on its yield but have a better growth effect than its biochar. This therefore implies that a farmer should use Leucaena instead of biochar since it has a better effect on the growth of maize and is as well less costly. The study also implies that L. leucocephala and its biochar increases the productivity of the soil thus contributing to sustainable production. The study recommends that biochar should be applied at different rates and the study should be conducted for a longer period to realize significant differences. It also recommends that soil analysis should be replicated for each treatment to compare effects among the treatments.
Dušične tvari kao parametri kvalitete Livanjskog i Travničkog sira
Authors: Hrković-Porobija Amina , Batinić Vinko , Ohran Husein , Kavazović Aida , Softić Almira , Vegara Mensur , Hodžić Aida
Published: July 2019

Istraživanje autohtone proizvodnje Livanjskog i Travničkog sira ima za cilj očuvanje tradicije, organizirane proizvodnje i plasmana na tržišta izvan domicilne regije. Autohtoni sirevi su raznovrsnijeg okusa, arome i konzistencije u odnosu na industrijski proizvedene sireve, gdje je tehnologija definirana, a uvjeti proizvodnje kontrolirani. Nadmorska visina, kvalitetna voda i hrana nisu dovoljni čimbenici za trajno održavanje kvalitete autohtonih sireva. Na osnovi standardizacije tehnoloških postupaka proizvodnje može se proizvesti sir specifičnog obilježja. Cilj istraživanja bio je odrediti i komparirati ukupni dušik i dušične frakcije u dva autohtona sira – Livanjskom i Travničkom, ovisno o terminu uzorkovanja (srpanj, kolovoz i rujan). Za anlizu su uzorci sira uzeti nakon 90 dana zrenja u izvornim uvjetima okoline. U uzorcima sira određivan je ukupni dušik i dušične frakcije. Određivanje sadržaja ukupnog dušika (TN), kao i dušika topljivog u vodi pri pH 4,6 (SN-4,6) i 12% trikloroctenoj kiselini (TCA-SN) provedeno je metodom po Kjeldahlu. Vrijednosti TN, SN-4,6 i TCA-SN u uzorcima Travničkog sira bile su niže u odnosu na uzorke Livanjskog sira pri svakom terminu uzorkovanja. Najveće vrijednosti indeksa SN-4,6/TN i TCA-SN/TN kod oba ispitivana sira utvrđene su u sirevima proizvedenim od mlijeka prikupljenog tijekom rujna. Indeksi zrenja su bili viši u uzorcima Travničkog sira, što ukazuje na povećanu primarnu proteolizu u odnosu na Livanjski sir, to može biti rezultat specifičnosti biljnog pokrivača i ispaše ovaca na nižoj nadmorskoj visini.
Sadržaj kadmija, žive i željeza u jetri i bubrezima janjadi na području općina Kakanj i Zenica
Authors: Muratović Salko , Muratović Adnan , Hadžić Dženan , Čengić-Džomba Senada , Džomba Emir , Brodlija Kemal , Korać Fehim
Published: July 2019

U radu su prikazani rezultati istraživanja opterećenosti teškim metalima na relaciji tlo-biljka-životinja područja Srednje-bosanskog kantona. Istraživanja su obuhvatila analizu sadržaja kadmija (Cd), žive (Hg) i željeza (Fe) u jetrenom i bubrežnom tkivu domaće janjadi. S područja općine Kakanj žrtvovano je 8 janjadi, od kojih su uzeti uzorci tkiva jetre i bubrega, a Zenice 7 janjadi, od kojih su također uzeti uzorci tkiva jetre i bubrega. Sadržaj teških metala (Cd, Hg i Fe) u uzetim uzorcima, utvrđen je na ICP-MS (masena spektrometrija s induktivno spregnutom plazmom), u skladu s evropskim standardima (EN 13805 : 2002, IDT) i (EN 15763, 2009, IDT). Utvrđena srednja količina Cd u uzorcima tkiva jetre s područja općine Kakanj iznosila je 0,115, a Zenice 0,261 mg/kg. Srednja vrijednost količine Cd u uzorcima tkiva bubrega sa područja općine Kakanj iznosila je 0,197, a Zenice 0,476 mg/kg. Sadržaj kadmija je veoma varijabilan na oba lokaliteta. Nije utvrđena statistički značajna razlika između lokaliteta. Općenito, sadržaj kadmija je ispod gornje granice dozvoljene količine prema Direktivi Europske Komisije. Utvrđene količine Fe na oba istraživana lokaliteta su znatno ispod gornje granice dozvoljenih vrijednosti. Na oba lokaliteta u uzetim uzorcima istraživanih tkiva nije utvrđena prisutnost žive.
Zatvaranje horizontalnog silosa - postoji li alternativa plastičnoj foliji?
Authors: Vranić Marina , Bošnjak Krešimir , Čačić Ivana
Published: July 2019

Cilj siliranja voluminozne krme je proizvodnja konzervirane krme za hranidbu domaćih životinja. Siliranje podrazumijeva fermentaciju ugljikohidrata, osobito onih topivih u vodi, u kiseline koje krmu konzerviraju i čuvaju u nepromijenjenom obliku do otvaranja silosa. Zatvaranje silosa je zadnji korak u proizvodnji fermentirane krme. Utjecaj pravilnog i pravovremenog zatvaranja silosa na kvalitetu silirane biljne mase je izražen kod siliranja biljne mase u horizontalne silose gdje pokrov treba zaštititi veliku površinu, a time i veliku količinu krme od kvarenja. Kvarenje krme koja se silira nastaje zbog zaostajanja veće količine kisika u biljnoj masi ili naknadnim prodorom kisika u biljnu masu koja se silira. Rezultati produljene aerobne faze ili naknadnog prozračivanja silosa su veći gubitci hranjivih tvari silirane krme, niža konzumacija silaže i niska proizvodnost životinja, mogući zdravstveni problemi životinja te negativan utjecaj na ekonomiku farme. Pokrovi za horizontalne silose moraju zadovoljiti određene standarde kvalitete i moraju dobro prianjati uz biljnu masu. U tu svrhu se najčešće koriste i neprekidno razvijaju nove generacije plastičnih folija. Ograničenja korištenja plastičnih folija za zatvaranje silosa su puno ljudskog rada, moguća oštećenja folija te velike količine plastike koje treba ekološki prihvatljivo zbrinuti. Alternativna rješenja plastičnim folijama za zatvaranje horizontalnih silosa još nisu dala zadovoljavajuće rezultate za širu primjenu u praksi jer njihovo korištenje rezultira nižom hranjivošću fermentirane krme i/ili im je previsoka cijena koštanja u usporedbi s korištenjem plastične folije.
Utjecaj porodne mase na dnevni prirast prasadi visokoplodnih krmača
Authors: Škorput Dubravko , Dujmović Zrinko , Luković Zoran
Published: July 2019

Legla visokoplodnih krmača često karakterizira varijabilnost porodnih masa prasadi i češća pojava lagane prasadi manje vitalnosti, što može negativno utjecati na proizvodne pokazatelje prasadi u kasnijim fazama uzgoja. Stoga je cilj rada bio utvrditi utjecaj porodnih masa prasadi na farmi visokoplodnih krmača na dnevne priraste prasadi u laktaciji i uzgoju. U istraživanje je bilo uključeno 296 prasadi iz prasenja 25 krmača hibridne linije Pen Ar Lan u razdoblju između prosinca 2014. i siječnja 2015. Analiziran je prosječni dnevni prirast prasadi od rođenja do kraja razdoblja uzgoja u dobi od 83 dana. Porodna masa značajno je utjecala na dnevne priraste prasadi tijekom laktacije i uzgoja. Prasad koja je pripadala razredima manjih porodnih masa imala je značajno manje dnevne priraste u odnosu na prasad koja je pripadala razredima s većim porodnim masama. Dobiveni rezultati upućuju na potrebu poduzimanja mjera s ciljem smanjenja broja avitalne prasadi manjih porodnih masa prasadi kako bi se omogućilo bolje preživljavanje i zadovoljavajući rast prasadi iz legala visokoplodnih krmača.
Impacto de las redes sociales en el sector del enoturismo del Priorat
Authors: Quero Guerrero Joan , Caicedo Aldaz Julio Cesar , Cedeño Alcivar Lenin Landivar , Zúñiga Chamorro Cristian Roberto
Published: July 2019

La eclosión del enoturismo ha supuesto para el sector vitivinícola catalán entrar en una nueva etapa dónde se tiene que comprender cuál es el producto que se espera, cómo lo espera el cliente y dónde tienen que ir las empresas a buscar a los clientes. Es un segmento en alza, que necesita de un trabajo constante y, a menudo, discreto. ¿Cómo pueden las redes sociales posicionar a

una empresa y diferenciarla del resto? ¿Lo están haciendo las empresas del Priorat? Uno de los ejes dónde aún se encuentran lejos de Burdeos o la Toscana es con el nivel de conexión con los clientes. En este trabajo analizaremos esta conexión des del punto de vista de las redes sociales, un paradigma aún por trabajar y que tiene dos hándicaps de primera mano. Así mismo Ylera (2007) define enoturismo como un fenómeno en el que los mundos del vino y turismo. Se funden para ofrecer una combinación de sus respectivas culturas, magias y atractivos. Otros autores mantienen la misma idea a la hora de definir el enoturismo como Imagen, ocio, cultura, salud y muchas cosas que acompañan al vino y que en cierto Modo todavía en España no se sabe aprovechar (Del Rey y Latre, 2007).
Necesidad de generar proyectos alineados a la política regulatoria del sector transporté, para combatir la tasa de mortalidad promovida por los accidentes de tránsito y que afecta a la economía del Ecuador
Authors: Chamba Bastidas Lenin Agustín , Moreno Albuja María Del Carmen , Cortez Manzano Rómulo Agustín , Carrera Silva Katherin Alejandra
Published: July 2019

La ciencia economía es una ciencia social que tiene una estrecha relación con la regulación y la tasa de mortalidad generada por los accidentes de tránsito terrestre, desde la asignación de recursos para gestionar la política regulatoria que busca minimizar la tasa de mortalidad hasta los recursos que se destina para invertir en herramientas que permitan y habiliten la movilidad y tránsito en el Ecuador. Anualmente alrededor de 1,3 millones de personas fallecen por temas de accidentes de tránsito según el Plan Mundial para el Decenio de Acción para la Seguridad Vial 2011 – 2020, mientras que en el Ecuador la tasa de mortalidad es del 16% en el año 2013 y 13% en el año 2018 por cada 100.000 mil habitantes, si bien la tasa baja para el 2018, es importante resaltar que la gestión no es suficiente para bajar la tasa o mantener la tendencia a la baja. Si relacionamos este problema con el PIB, los costos sociales y económicos por accidentes y lesionados, ascienden al 1% del PNB en los países de ingresos bajos, el 1,5% en los países medios y el 5% en los países con ingresos altos. El trabajo está sustentado en una revisión breve del ámbito legal, el ámbito de la planificación nacional e internacional y de los datos obtenidos en la Agencia Nacional de Tránsito del Ecuador, institución que se encarga de administrar dicha información. El objetivo es analizar la información recabada mediante la metodología elegida a efectos de establecer un juicio de valor respecto de la problemática planteada.
Violación del derecho a la defensa de las personas y el debido proceso en los juicios de jurisdicción coactiva en el art. 968 del código de procedimiento civil
Authors: Loza Torres Andrés Gustavo , Colcha Ortiz Raquel Virginia , Carrera Silva Katherin Alejandra , Moreno Albuja María Del Carmen
Published: July 2019

El presente trabajo de investigación, tiene como objetivo primordial, realizar un estudio y análisis jurídico acerca de lo que en nuestro país es el cumplimiento del derecho constitucional a la defensa de las personas y el debido proceso en los juicios de jurisdicción de coactivas, su procedimiento legal, parámetros que deben ser respetados, excepciones a este proceso, la inobservancia a los derechos constitucionales y a la importancia de dichos juicios dentro de nuestra sociedad. Este tema ha sido de vital trascendencia debido a los sucesos ocurridos en los últimos años dentro de nuestro país, ya que el Estado Ecuatoriano ha tomado a su cargo a organismos públicos del mismo, tal como menciona al BNF, sucursal Alausí como ente fundamental de investigación, provocando con esto, que las personas naturales o jurídicas que adeudaban rubros a este organismo, ya no tengan deudas meramente civiles, recuperables por juicio ejecutivo, sino poniéndoles en la difícil situación del juicio coactivo. Dentro del trabajo de investigación propuesto, enfocaré en determinar si el juicio coactivo viola derechos y garantías constitucionales, a fin de establecer si la tutela efectiva y la seguridad jurídica están siendo respetadas en cada uno de los procesos. Al analizar cada uno de los procesos coactivos en el BNF, sucursal Alausí en liquidación se establecerá la eficacia en la recuperación de cartera vencida por parte del organismo competente y el impacto de este en la sociedad. También se establecerá si la jurisdicción coactiva tiene las mismas garantías que la justicia ordinaria, o si por el hecho de ser el Estado el que impulsa el juicio tenga privilegios y beneficios de los cuales no goza ninguna otra persona natural o jurídica que impulse el juicio en los procesos ordinarios.
Procedimientos de planificación de la gestión de calidad como factor fundamental para el desarrollo de las universidades
Authors: Cárdenas Fragozo Norelys , Berrio Caballero Hobber , Alfaro Camargo Carlos
Published: July 2019

Este capítulo presenta los resultados de un estudio realizado por los investigadores de la universidad de La Guajira. De la investigación que lleva por título “la innovación organizacional para la gestión de la calidad en las Instituciones públicas de Educación Superior del municipio de Riohacha –Colombia., lo cual indica según los resultados obtenidos que los procesos de planificación que se llevan a cabo son factores fundamentales para el desarrollo de las universidades. El objetivo se centró en describir los procesos de gestión de la calidad en las universidades públicas del municipio de Riohacha-Colombia. Cuya metodología fue de enfoque cuantitativo, diseño de campo de corte transversal y no experimental, descriptivo. La muestra estuvo constituida por 23 sujetos, distribuidos de la siguiente manera; decanos de las distintas facultades,  coordinadores de programa, personal de la oficina de planeación, vicerrectoría de investigación y extensión, vicerrectoría académica de las universidades públicas del municipio de Riohacha,  Se utilizó como técnica de recolección de datos la encuesta utilizando la escala Likert con cinco (5) alternativas de respuesta, mediante la distribución de frecuencia absoluta y relativa orientada a detallar en forma sistemática las características de la variable gestión de la Calidad. Los autores que soportaron la dimensión procesos de gestión de la calidad fueron Moreno (2001, Juran (2001), teniendo en cuenta el resultado final de la dimensión en la media fue de 4,2 ubicándose en la categoría presente en atención al baremo así mismo, la dispersión fue de 0,8 entendiéndose que hubo un nivel de dispersión alto, indicando esto que entre mayor es la dispersión hay esparcimiento en los datos. De acuerdo a este análisis, las universidades del municipio de Riohacha cuentan con un proceso de planificación donde se establecen, implementan, mantienen y mejoran continuamente un Sistema de Gestión de la Calidad (SGC), incluyendo los procesos necesarios y sus interacciones de acuerdo con los requisitos de esta norma.
Tubercular Lesions in Brain Parenchyma
Authors: Chowdhury Forhad Hossain , Mohammad Nur , Haque Mohammod Raziul , Hossain Zahed , Salam Md Abdus , Sarker Mainul Haque
Published: July 2019

Background: Preoperative neuro-radiological features of tuberculosis involving brain lesions may mimic neoplastic lesions of brain & skull base and post operative histopathological study or response to empirical anti-tubercular therapy brings the ultimate diagnosis.

Objective: Here we present our experience of 76 cases of cerebral and cerebellar tuberculosis that was managed surgically with anti-tubercular drugs or medical treatment alone without histopathological confirmation.

Methodology: All cases of brain parenchymal tuberculosis confirmed histopathologically after surgery or confirmed by succesfull conservative treatment with anti-TB from January 2008 to June 2015 were included for study. Tubercular meningitis was excluded from the study. Patients underwent some form of surgery that confirmed the tuberculosis by histopathologically. Patients with suspected tubercular lesion in brain were treated empirically with antiTB. Post operative imaging was done with CT scan of brain or MRI of brain in immediate post operative period, six months after operation and 18 months after operation.

Results: 34 patients underwent surgery to confirm the tuberculosis and 44 patients with suspected tubercular lesion in brain were treated empirically with antiTB of which 40 patients responded successfully and rest 4 patients did not responded and underwent surgical excisional biopsy. Common clinical features include features of raised ICP with focal signs and symptoms. Concurrent other systemic tuberculosis was found in three cases. One patient had history of full course anti-tubercular therapy for pulmonary tuberculosis 20 years back.

Conclusion: In suspected TB lesions, conservative treatment without histopathological diagnosis may be adopted with ultimate same result

Bangladesh Journal of Infectious Diseases, December 2018;5(2):45-60
In New Geon Extra Peritioneal Caesarean Section An Observational Study
Authors: Daise Tahmina Afreen , Ara Begum Hosne , Tasnim Saria , Ahsan AKM Badrul , Chowdhury Sushmita Ray , Imran Shahed
Published: July 2019

This study was designed to find out the maternal and perinatal outcome among 80 women undergoing extraperitoneal cesarean section. This observational study was conducted at Institute of Child and Mother Health, Matuail, Dhaka from 1st March 2013 to 28th February 2014. Data were collected by structured questionaire ith the writen consent of patients irrespective of routine and emergency cases where the procedure was successful in all patients. During operation, time was taken from open to close, incision to delivery of baby, total amount of blood loss during procedure, intraoperative complications, APGAR score of newborn were documented. Time required for return of bowel sound mobilization of patient within 24 hour and, duration of hospital stay were also included. Success rate of extra peritoneal CS was 100%, Time taken from incision to delivery was ≤6 minutes in 62.2% cases, time taken from incision to closure was between 31-45 min in 72.5% cases, blood loss ≤500 ml in 62% cases, return of bowel function between 5-8 hours in 52.5%, mobilization within 24 hours in 52.5%, neonatal one minute APGAR score ≥7 in 93.91%.  As a surgical form of infection prophylaxis extraperitoneal cesarean section can be applied to avoid serious post-operative pelvic infections and its complications Extraperitoneal cesarean section would be a rational practice of cesarean section in the modern era.

Bangladesh Med J. 2017 Sep; 46 (3): 94-96
Case study of Dyadic death in Bangladesh: by Hanging, Strangulation and Poisoning
Authors: Sadek Ahmad , Halim Kazi Shafiqul
Published: July 2019

Here described two cases where mother is the main perpetrators of the event and the victims were their children in the age group of 1 year to 12 years. In 1st case 35 years lady killed her three daughters ages 12, 9, 1 by strangulation then hanged in south surma Sylhet city. In 2nd case A 32 years old married women killed her two sons (ages 5 & 8yrs ) by poisoning and later she died by hanging in Sylhet city . Autopsy examination revealed ligature mark over neck consistent with that of antemortem  hanging  and ligature marks round the child’s neck were strangulation case also poison found by chemical examination. So it’s time to take awareness within community and take prevention such like notorious incident.

Bangladesh Med J. 2017 Sep; 46 (3): 104-106
Co-existence of Systemic Lupus Erythematosus and Ankylosing Spondylitis - A Case Report
Authors: Nakarmi Shweta , Ahmed Shamim , Shahin Md Abu , Shazzad Md Nahiduzzaman , Mahmood Tareq , Haq Syed Atiqul
Published: July 2019

Co-existence of systemic lupus erythematosus and ankylosing spondylitis is not common. In this report, we present a 24-year-old woman with both the entities diagnosed in the course of time. Initially she presented with malar rash, photosensitivity, oral ulcer and polyarthritis. Her ANA and anti-Smith antibody were positive, but ant-ds DNA was negative. With these features, she was diagnosed as a case of systemic lupus erythematosus. Few months later, she was diagnosed with ankylosing spondylitis on the basis of inflammatory back pain and bilateral sacroilitis.

Bangladesh Med J. 2017 Sep; 46 (3): 100-103
Obstructive Nephropathy in Children – A Review
Authors: Ferdous Shahana , Roy Ranjit Ranjan , Ahmmed Md Faysal , Shazzad Md Nahiduzzaman
Published: July 2019

Obstructive nephropathy is any affection of the urinary tract characterized by impairment of urine flow through the tract and which, if left untreated, will cause progressive renal damage. Causes in children are congenital or acquired. Congenital causes are pelvi-ureteric junction obstructions, posterior urethral valves (PUV), urethral atresia, phimosis and meatal stenosis. The acquired causes are calculi, post-traumatic and post-inflammatory strictures and meatal stenosis. There are some manifestations like prune-belly syndrome, hydronephrosis and renal failure. Diagnostic investigations include ultrasonography, intravenous urography, cystography and renography. Advanced technologies have impacted on the treatment of the different lesions such as utero vesico-amniotic shunt and endoscopic valve ablation for PUV and minimally invasive techniques for urolithiasis. Nephrectomy may be indicated in a unilateral damaged kidney. Sometimes treatment may fail because of pretreatment irreversible renal damage. Such as end-stage renal failure is an indication for renal transplantation. So, proper treatment is essential to prevent end-stage renal failure.

Bangladesh Med J. 2017 Sep; 46 (3): 107-113
Clinical and ElectrophysiologicAspects of Guillain Barre Syndrome among Children: Experience at Referral Tertiary Care Hospital in Bangladesh
Authors: Debnath Bithi , Hussain Mohammad Enayet , Haque Nazmul , Khan AFM Al Masum , Mian Md Ferdous , Islam Md Nahidul , Saha Narayan Chandra , Alam Md Badrul , Hoque Md Azharul , Mohammad Quazi Deen , Chowdhury Rajib Nayan
Published: July 2019

Background: Guillain Barre Syndrome (GBS) is an acute polyradiculopathy which is quite common in all ages.

Objective: The aim of this study was to evaluate the clinical and electrophysiologicaspects of Guillain Barre Syndrome (GBS) in children.

Methodology: This cross-sectional study was carried out in the Department of Neurophysiology of National Institute of Neurosciences and Hospital, Bangladesh from July 2016 to June 2018. Patients under 18 years of age fulfilling Brighton diagnostic criteria for GBS were included in this study. These patients were evaluated by detailed history, physical examination, and electrophysiological findings.

Results: A total of 82 patients of GBS were enrolled in this study. The mean age was 12.93± 5.02 years (range 1 to<18 years). Most of the patients were male (64.6%) and from the middle-income group (70.73%). About Fourty eight percent of patients had a history of preceding illness among which gastrointestinal infection(24.3%) was the most common. Tingling and paresthesiaswas complained by 32.4% of patients as the first symptom. AMAN(61%) was the most common GBS variant followed by AIDP(26.8%). 9 (11%) patients needed ICU support among them AIDP was more frequent.

Conclusion: AMAN is the most common variant among children in this population by electrophysiologic testing.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 2-7
Assessment of Serum Magnesium Level in Patients with Bronchial Asthma
Authors: Rashid Md Haroon Ur , Chowdhury Md Rezaul Karim , Faraji Md Anwarul Hoque , Rahman Shamimur
Published: July 2019

Background: Asthma is one of the most common chronic diseases worldwide and has been increasing in prevalence over the last few decades. Magnesium (Mg++) has been shown to relax bronchial smooth muscle and influence the function of respiratory muscles. Hypomagnesemia has been associated with diminished respiratory muscle power.

Objective: The purpose of the present study was to assess the serum Mg++ level in bronchial asthma patients during stable state and during exacerbation (Acute severe asthma).

Methodology: This comparative cross-sectional study was conducted in the OPD and IPD of Department of Pulmonology at Enam Medical College and Hospital, Savar, Dhaka, Bangladesh and this study was carried out from January 2017 to December 2017 for a period of one year. Subjects were enrolled from Enam Medical College and Hospital. Patients diagnosed as bronchial asthma were taken as group A and healthy individuals were as a group B. The asthmatic patients were divided into groups those having chronic stable bronchial asthma and those having acute severe asthma.

Results: Serum Mg++ level was significantly (p=0.000) lower in asthmatic patients 1.59±0.24 as compared with healthy controls (2.05±0.34) and significantly lower (p=0.006) in asthmatic patients during exacerbation (1.49±0.27) when compared to stable asthmatics (1.69±0.15). Asthmatic on ≥3 drugs has significantly (p=0.000) lower serum Mg++ 1.43±0.23 than those on <3 drugs (1.65±0.22).

Conclusions: Serum Mg++ level was significantly lower in asthmatic patients during exacerbations compared with stable asthmatics.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 38-41
Use of CT-Scan for Predicting Mortality of Acute Intracerebral Haemorrhagic Stroke within 7 and 28 Days
Authors: Huda Md Durrul , Sana Niranjan Kumar , Ahmad Quamruddin , Uddin Md Kafil , Alahi Md Munzur , Islam Md Tariqul , Ara Showkat , Rahman Md Hafizur
Published: July 2019

Background: Recognition of factors affecting morbidity and mortality of a disease helps in the proper management of a disease. CT scan of Brain is an essential investigation for all stroke patients. Identifying different characteristics of the CT findings of stroke patients which affect morbidity and mortality will help in the specific management of stroke patients. Thus this study was done to identify such factors from CT scan of Brain which will help in the proper management of stroke patients.

Objectives: The aim of this present study was to determine the 7th and 28th days’ mortality rate of acute intracerebral hemorrhagic stroke and to determine the predictors of mortality.

Methodology: Consecutive CT scan proven stroke patients following ICH were studied in the department of Radiology & Imaging at Rajshahi Medical College, Rajshahi, Bangladesh in collaboration with the Department of Neurology of Rajshahi Medical College, Rajshahi from January 2012 to December 2013. Site, size and volume of haematoma, midline shift, pineal gland displacement, hydrocephalus and intraventricular extension of haemorrhage were correlated with the mortality within 7th and 28th days of acute stroke. Risk factors like hypertension, smoking, diabetes and alcoholism were also recorded.

Result: Ninety-nine consecutive CT scan proven stroke patients following ICH were studied. The 28-day mortality of intracerebral hemorrhage was 44.44% and it was 29.30% within the first 7 days of onset. Maximum number of death occurred in brainstem haemorrhage (75%), initial haematoma volume 61 to 80 ml (89.47%), >80 ml (91.7%), pineal gland displacement >3mm (79.5%), septum pellucidum displacement >5 mm (72.4%), ventricular extension (88.57%), and hydrocephalus (76.74%).

Conclusion: The present study shows that deaths within 7th and 28th day of acute haemorrhagic stroke are correlated with the initial CT findings which could be regarded as a good predictor of mortality.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 42-46
Rate of Distribution of Breast Lump in Different Quadrants with Their Cytological Findings in Both Sex
Authors: Nahar Nazmun , Iqbal Mohammed , Rahman Kazi Md Shahidur , Md Arif Nazim Uddin , Rahman Md Mizanur , Naheen Towhida , Alam Mohammed Safiul , Das Soma
Published: July 2019

Background: The breast lump is a localized swelling, protuberance, bulge, or bump in the breast that feels different from the breast tissue around it or the breast tissue in the same area of the other breast.

Objective: The purpose of the present study was to find out the frequency of breast lump in different quadrants and their cytological findings.

Methodology: The present study was carried out at the Department of Pathology, Chittagong Medical College, Bangladesh one-year period from May 2005 to June 2006. This study was cross sectional which included 110 cases of breast lump. The patients with breast lump were received from indoor and outdoor patient Department of Surgery, Chittagong Medical College, Bangladesh. The patient presents with definite palpable lump, irrespective of age and sex were included in this study.

Result: This study shows only 1.8% male were found central quadrant individual breast. In female maximum (46.4%) were found in upper & outer quadrant individual breast. Right sided of affected breast in highest percentage of upper & outer quadrant individual breast (21.8%). Also shows left side of affected breast in highest percentage of upper & outer quadrant individual breast (24.5%). It was observed that maximum (34.5%) upper & outer quadrant individual breast was seen in benign lesion and (3.6%) were suspicious. But maximum (12.7%) were show multiple in malignant lesion.

Conclusion: In conclusion highest frequency of patients are reported in upper outer quadrant breast lump followed by multiple, central, lower & inner and lower & outer. It also observed that the upper outer quadrant is the most commonly affected quadrant in benign and multiple quadrant the malignant breast neoplasms.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 69-71
Structural Modeling of Institute of Entrepreneurship in Russia
Authors: Sazanova Svetlana L.
Published: July 2019

Entrepreneurship plays an important role in the modern global economy; the share of products of small and medium enterprises in the gross product and exports not only of the developed but also of developing countries is growing. Innovation processes cover all sectors of the economy, and more and more people are involved in entrepreneurial activity, which contributes to the penetration of entrepreneurial thinking and business values in all areas of the socioeconomic life of society. The Institute of Entrepreneurship plays an increasingly prominent role in the institutional environment of socio-economic systems. This actualizes the problem of studying the relationship of the institution of entrepreneurship with the institutions of law, culture, management. This requires a methodology that allows you to explore the impact on the institute of entrepreneurship not only economic, but also non-economic factors. The methodology of the “old” institutionalism possesses such a tool, it is structural modeling (pattern modeling), which allows to explore the diversity of interrelationships of the institution of entrepreneurship with other components of the institutional and economic environment. The article explored the features of the development of the institution of entrepreneurship in Russia, established the relationship between the institution of entrepreneurship, values, motives and incentives for entrepreneurial activity, built a structural model of the institution of entrepreneurship based on the methodology of the old institutionalism (pattern modeling). The structural model of the institution of entrepreneurship reveals the relationship between the institution of entrepreneurship, the values of entrepreneurial activity, its motives and incentives; as well as the relationship between the institution of entrepreneurship with the institutions of governance, cultural and religious institutions, legal institutions and society.
Self Assessment Pengelolaan Masalah Pada SIADIN Universitas Dian Nuswantoro berbasis COBIT 5
Authors: Oktaviani Mella Cynthia , Adnan Fajrian Nur
Published: July 2019

Universitas Dian Nuswantoro merupakan salah satu perguruan tinggi swasta di kota Semarang yang memberikan jasa pendidikan formal untuk gelar Diploma III (D3), Sarjana (S1), dan Magister (S2). Untuk sebuah Universitas, teknologi informasi berupa sistem informasi telah menjadi aspek penting dalam proses pendidikan, penelitian, administrasi, dan layanan. Universitas Dian Nuswantoro sudah menggunakan sistem informasi yang diberi nama SiAdin.  SiAdin merupakan sistem informasi akademik yang saling terintegrasi dengan berbagai sistem informasi lainnya. Dalam pelayanannya, SiAdin terdapat beberapa masalah yang sering berulang seperti masalah data nilai transkrip yang berbeda, materi perkuliahan yang eror ketika di upload, dan server yang sering down saat ujian online dan kegiatan penginputan KRS. Dari permasalahan diatas maka akan dilakukan Self Assessment berdasarkan domain Delivery, Service, And Support (DSS) yang berfokus pada pengelolaan masalah yaitu DSS03 (Manage Problems) yang mengacu pada COBIT 5 dengan mengumpulkan data melalui wawancara, kuesioner dan survey lapangan / visitasi. Dari hasil pengumpulan data didapatkan nilai capability level saat ini berada pada level 1 sebesar 64,12% dengan status L (Largely Achieved). Hasil dari penelitian ini adalah nilai capability level, nilai gap, dan rekomendasi/usulan strategi perbaikan, dokumen dan SOP yang dibutuhkan organisasi.Kata kunci—COBIT 5, Self Assessment, DSS03, Pengelolaan Masalah, SiAdin
Implementasi Enterprise Architecture Zachman Framework pada Sistem Informasi Akademik Universitas Dian Nuswantoro Semarang
Authors: Kusumawati Yupie , Sitorus Melati Anggreni , Sani Ramadhan Rakhmat
Published: July 2019

Pusat Data dan Informasi (PDI) merupakan salah satu unit pelaksana teknis yang berperan penting dalam mendukung terlaksananya proses perkuliahan di UDINUS. Namun dalam melaksanakan tugas dan tanggung jawab PDI memiliki permasalahan, dimana terjadi error pada Sistem Informasi Akademik Universitas Dian Nuswantoro (SIADIN) saat dioperasikan oleh user dan kurangnya integrasi antar sistem. Dalam menangani error tersebut PDI mengecek kode program dan melakukan perbaikan, namun untuk porgrammer yang belum mengetahui proses pembangunan dan pengembangan SIADIN memiliki kesulitan dalam melakukan perbaikan error (penambahan fungsi) yang dibutuhkan. Kesulitan tersebut disebabkan oleh beberapa hal yaitu kurangnya dokumentasi yang dimiliki terkait dengan pembangunan sistem, stakeholder tidak dilibatkan sepenuhnya, kemampuan dalam melakukan analisis terhadap potensi kemungkinan adanya kesalahan sangat minim dan tidak mempunyai framework sebagai acuan pengembangan SIADIN. Maka dari itu penelitian ini dilakukan untuk menciptakan blueprint IT sistem informasi akademik pada core process dan Prototype sistem informasi akademik pada admin yang dikembangkan berdasarkan blueprint IT dengan menggunakan Zachman Framework sebagai kerangka kerja enterprise architecture untuk melakukan dokumentasi terhadap pengembangan sistem dengan memetakan kedalam 36 sel. Dari penelitian ini diperoleh blueprint IT dan prototype berbasis Objected Oriented Programming yang dapat digunakan sebagai acuan untuk membangun, mengembangkan dan mendokumentasikan sistem.Kata kunci— Enterprise Architecture, Zachman Framework, Blueprint IT
PENGARUH MOBILISASI DINI TERHADAP KUALITAS HIDUP IBU POST SEKSIO SESAREA DI RSUD TUGUREJO SEMARANG
Authors: Tyasning Erlina Ekawati , Prasetyorini Heny
Published: July 2019

ABSTRAK

 

Rendahnya kualitas hidup ibu postpartum dengan seksio sesarea, disebabkan oleh kebutuhan masa postpartum meliputi kebutuhan fisik, psikologis, dan sosial. Ibu post seksio sesarea mengungkapkan perasaan takut, kecewa, marah, maupun frustasi karena kehilangan kontrol, hanya berbaring dan membatasi pergerakan tubuhnya karena takut merasakan nyeri, sehingga memicu terjadinya komplikasi. Salah satu upaya mengurangi timbulnya komplikasi seperti tromboemboli dan mempercepat pemulihan kekuatan ibu, disarankan melakukan perawatan dengan mobilisasi dini. Mobilisasi dini merupakan suatu pergerakan, posisi atau adanya kegiatan yang dilakukan ibu setelah beberapa jam melahirkan. Tujuan perawatan mobilisasi dini adalah ibu postpartum dapat menjadi lebih kuat, sehat dan dapat melakukan aktivitas secara mandiri sehingga ibu memiliki kualitas hidup yang jauh lebih baik. Tujuan dari penelitian ini untuk mengetahui pengaruh mobilisasi dini terhadap kualitas hidup ibu post seksio sesarea. Jenis penelitian ini adalah penelitian eksperimen semu dengan desain post test-only non equivalent control group. Teknik pengambilan sampel menggunakan teknik non probability sampling. Metode yang digunakan dalam pengambilan sampel yaitu dengan consecutive sampling. Jumlah sampel 5 ibu post seksio sesarea. Penelitian dilakukan tanggal 19 sampai 25 Desember 2016. Hasil dari penelitian menunjukkan rata – rata setiap domain kualitas hidup ibu post seksio sesarea sebanyak 5 responden ( 100 % ) yang dilakukan mobilisasi dini mengalami kualitas hidup baik. Kesimpulan dari penelitian ini adalah kualitas hidup ibu post seksio sesarea setelah dilakukan mobilisasi dini sebanyak 5 responden ( 100 % ) mengalami kualitas hidup baik. Sehingga mobilisasi dini sangatlah berpengaruh untuk kualitas hidup ibu post seksio sesarea
GAMBARAN TINGKAT PENGETAHUAN PASIEN DIABETES MELITUS TENTANG PENYAKIT DIABETES MELITUS DI RSUD dr H SOEWONDO KENDAL
Authors: Ishab Noor Fitriardi , Chandra Prasetiya Hadi
Published: July 2019

ABSTRAK

 

Salah satu masalah kesehatan yang banyak dialami oleh masyarakat di Indonesia adalah penyakit Diabetes Melitus. Diabetes melitus merupakan sekumpulan gangguan metabolik yang di tandai dengan peningkatan kadar glukosa darah (hiperglikemia) akibat kerusakan pada sekresi insulin, kerja insulin, atau keduanya. Untuk mengatasi masalah Diabetes Melitus sangatlah sulit salah satunnya karena faktor pengetahuan masyarakat yang masih rendah. Pengetahuan mempunyai peran besar dalam perilaku kesehatan di masyarakat. Penelitian atau mini riset analitik kualitatif ini bertujuan untuk mengetahui gambaran tingkat pengetahuan diabetes mellitus tentang diabetes mellitus pada pasien di RSUD dr Soewondo Kendal. Pengambilan sampel menggunakan desain cross sectional dan teknik random di RSUD dr Soewondo Kendal. Hasil yang didapat menunjukkan sebagian besar pasien di RSUD dr Soewondo Kendal. memiliki tingkat pengetahuan kurang baik atau rendah tentang diabetes mellitus. Fasilitas kesehatan adalah tempat yang paling banyak untuk mendapatkan informasi kesehatan, itu disebabkan karena oleh beberapa faktor seperti usia, pendidikan, dan pekerjaan.peneliti menyarankan kepada RSUD dr Soewondo Kendal agar bekerjasama dengan dinas kesehatan dan puskesmas di kabupaten kendal untuk meningkatkan promosi kesehatan di plosok desa khususnya tentang diabetes mellitus.
UPAYA PENURUNAN INTENSITAS NYERI PERSALINAN KALA 1 FASE AKTIF DENGAN MUROTTAL AL-QUR’AN DI RUMAH SAKIT UMUM DAERAH KOTA SEMARANG
Authors: Suprapti Suprapti , Wirawati Maulidta Karunianingtyas
Published: July 2019

ABSTRAK

 

Proses persalinan merupakan proses alamiah yang akan dialami wanita hamil yang dapat menimbulkan rasa ssakit, dan bahkan dapat menyebabkan kematian. Nyeri persalinan kala 1 dapat diurangi dengan menggunakan metode farmakologi dan non farmakalogi. Murottal al-qur’an merupakan metode non farmakologi dengan distraksi audio menggunakan surat-surat dari al-qur’an yaitu surah Al-fatihah, Al-ikhlas, Al-falaq dan Annas. Mengetahui pengaruh terapi murottal terhadap penurunan intensitas nyeri persalinan kala 1 fase aktif di RSUD Kota Semarang. Desain dalam penelitian ini adalah penelitian deskriptif. Populasi dalam penelitian ini adalah seluruh ibu persalinan kala 1 fase aktif, ibu beragama islam, ibu mempunyai fungsi pendengaran yang baik, ibu kooperatif di RSUD Kota Semarang. Teknik pengambilan sampling menggunakan teknik non probability sampling dengan pendekatan purposive sampling yaitu sebanyak 5 responden. Hasil penelitian yang dilakukan pada bulan Desember 2016 sampai Januari 2016 diperoleh hasil rata – rata sebelum diberikan terapi murottal al-qur’an adalah (8.6). Rata - rata setelah pemberian terapi murottal al-qur’an adalah (5.2). Dari hasil penelitian menunjukan adanya perbedaan rerata penurunan intensitas nyeri persalinan kala 1 fase aktif sebelum dan sesudah pemberian terapi murottal al-qur’an adalah (3.4). Kesimpulan dari penelitian ini menunjukkan adanya pengaruh murottal al-qur’an terhadap penurunan intensitas nyeri persalinan kala 1 fase aktif sebagian besar ibu bersalin mengalami nyeri sedang (60%).
PENERAPAN TERAPI MUSIK TERHADAP PENURUNAN KECEMASAN PADA PASIEN PRE OPERASI FRAKTUR DI RUMAH SAKIT DARAH K.R.M.T WONGSONEGORO
Authors: Mulfiroh Susi , Wahyuningsih Wahyuningsih
Published: July 2019

Latar belakang : Kecemasan merupakan reaksi pertama yang muncul atau dirasakan pasien dan keluarganya disaat pasien harus di rawat mendadak atau tanpa terencana begitu mulai masuk rumah sakit. Berbagai upaya telah dilakukan untuk mengurangi tingkat kecemasan, salah satunya dengan terapi non farmakologis yaitu dengan terapi musik. Pemberian terapi musik merupakan salah satu metode pemenuhan untuk mengurangi tingkat kecemasan. Tujuan studi kasus ini adalah untuk mengurangi tingkat kecemasan pada pasien pre operasi fraktur. Jenis penelitian ini adalah deskriptif dengan menggunakan metode pendekatan studi kasus. Subyek studi dalam penelitian ini adalah dua orang pasien pre operasi fraktur dengan kriteria pasien mengalami kecemasan. Penelitian ini dilakukan di RSUD K.R.M.T Wongsonegoro Semarang di ruang Nakula 01. Analisis penurunan tingkat kecemasan dilakukan dengan cara memberikan kuesioner tentang penurunan tangkat kecemasan. Hasil analisa dikatagorikan menjadi tidak cemas, kecemasan ringan, kecemasan sedang, kecemasan berat. Katagori ditentukan berdasarkana pengisian kuesoiner dari subyek. Hasil studi kasus menunjukan bahwa ada penurunan tingkat kecemasan dari kecemasan ringan menjadi tidak cemas setelah di berikanterapi musik. Rekomendasi perlu konsisten peawat dalam melakukanterapi musik untuk menurunkan tingkat kecemasan pada pasien pre operasi fraktur.
Pengaruh Pupuk P terhadap Pertumbuhan dan Produksi Beberapa Kultivar Padi (Oryza sativa L.) Gogo Lokal
Authors: Reis Alfredo Dos , Darwis Darwis , Rembon Fransiscus Suramas
Published: July 2019

Penelitian ini bertujuan untuk mempelajari pengaruh pupuk P terhadap pertumbuhan dan hasil beberapa kultivar padi gogo lokal pada lahan kering. Penelitian ini dilaksanakan di Desa Sindang Kasih Kecamatan Ranomeeto Barat.  dan Laboratorium Agronomi Fakultas Pertanian Universitas Halu Oleo Kendari. Variabel yang diamati yaitu tinggi tanaman (cm jumlah anakan produktif dan produksi t ha-1. Dari hasil analisis data secara statistik diperoleh bahwa var  padi gogo lokal dan perlakuan kultivar mandiri berpengaruh sangat nyata terhadap tinggi tanaman pada saat panen (cm), jumlah anakan produktif,  dan  hasil produksi t -1. Hasil tersebut menunjukkan bahwa ada pengaruh dosis pupuk dan varietas terhadap pertumbuhan dan produksi padi gogo, namun ada beberapa kultivar padi gogo lokal yang mempunyai  respon positif terhadap pertumbuhan dan hasil yang lebih baik bila dibandingkan dengan kultivar-kultivar  padi gogo lokal yang lainnya diantaranya varietas Lipi Go, kultivar Waburi-buri,kultivar Wangkomina dan kultivar Wakawandu. Hasil yang dicapai dalam penelitian ini adalah  (1) kultivar Waburi-buri 4,024 t ha-1 (2) varietas Lipi Go 4  4,004 t ha-1 (3) kultivar Pae Uwa 3,788 t ha-1   dengan dosis pupuk SP-36 360 dan 480 kg ha-1Kata kunci: Varietas Padi Gogo, Oriza sativa L., Pupuk P