bluuebunny/crossref_metadata_2025 huggingface dataset:
Uso do grafeno e nióbio na prática médica: uma revisão narrativa de literatura
Authors: Figueiredo Bárbara Queiroz de , Morais Álvaro Peixoto de , Brito Ana Clara Viana Soares , Roehrs Dieison Danrlei , Carneiro Heitor Laborão , Sousa Isabelle Gomes de , Araújo Letícia de Oliveira , Nagata Lorena Martins , Sousa Lunalva Gabrielli Veras , Gomes Maria Jacilene de Araújo , Alves Melina Fonseca Maia França Coury
Published: January 2022

Introdução: Os chamados nanomateriais são considerados por muitos, materiais que possuem sua estrutura restrita a dimensões de 1 a 100 nm. Os nanomateriais apresentam uma extensa faixa de aplicações como na biomedicina, na área de alimentos e agricultura, drogas e vacinas e principalmente na catálise. Objetivo: evidenciar as aplicações dos nanomateriais grafeno e nióbio na medicina, ressaltando seus resultados promissores nesse campo. Metodologia: Trata-se de uma pesquisa descritiva do tipo revisão narrativa da literatura. A pesquisa foi realizada através do acesso online nas bases de dados National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (Scielo), Cochrane Database of Systematic Reviews (CDSR), Google Scholar, Biblioteca Virtual em Saúde (BVS) e EBSCO Information Services, no mês de novembro de 2021. Resultados e discussão: O óxido de grafeno reduzido tem se mostrado um excelente agente fototérmico, permitindo a eliminação eficiente de tumores em experimentos in vivo, bem como, devido a excelente condutividade elétrica do grafeno promete melhorar a conversão das sinapses em movimento. Além disso, o uso de nióbio cresce no campo da medicina como elemento de liga para aumento de resistência mecânica para implantes ortopédicos biocompatíveis. Considerações finais: Assim, é possível afirmar que são muitos os benefícios que o grafeno e o nióbio, interligados com as nanotecnologias, gerarão à humanidade, e, principalmente aos avanços da medicina.
Planejamento estratégico situacional como ferramenta de promoção em saúde na gestão: revisão integrativa
Authors: Lima Ellaine Valéria Araújo da Silva , Santos Thais de Oliveira Carvalho Granado , Andrade Ana Gabriela Sabaa Srur de , Glória Wanessa Nobre do Carmo , Santos José Daniel Rodrigues dos , Ferreira Ilma Pastana , Moia Lizomar de Jesus Maues Pereira , Feitosa Laise Cristina Pantoja , Moraes Pilar Maria de Oliveira , Mendonça Xaene Maria Fernandes Duarte
Published: January 2022

Objetivo: Avaliar como ocorre o Planejamento Estratégico Situacional na Atenção Primária à Saúde (APS) no Brasil, e de que forma ele contribui para a gestão em saúde. Método: Trata-se de uma revisão integrativa de literatura (RIL), realizada no período de novembro de 2020 a abril de 2021. Os critérios de inclusão dos estudos foram: artigos em português, inglês e espanhol, publicados nos últimos 05 anos, que apresentassem em sua discussão considerações sobre a importância do planejamento estratégico situacional na gestão dentro da APS, indexados nas bases de dados LILACS e PUBMED, utilizando-se como descritores de assunto “atenção primária à saúde” e “planejamento estratégico”. Foram excluídas as publicações no formato de tese, dissertação, capítulo de livro e as que não tinham relação com o tema da pesquisa. Resultados: Foram encontradas 170 publicações. Após aplicação dos critérios de inclusão e exclusão, obteve-se 09 artigos dos quais emergiram temas quanto à importância do Planejamento Estratégico Situacional e como ele deve ser articulado em diversas áreas dentro da gestão na APS, promovendo metas e indicadores capazes de avaliar e monitorar resultados no planejamento. Conclusão: Os resultados desta revisão encontraram diferentes formas de aplicação do Planejamento Estratégico Situacional (PES) na gestão da atenção primária a saúde com foco na promoção e prevenção, os quais mostraram que ainda existem muitos desafios a serem enfrentados, porém, possíveis de serem trabalhados através da integração ensino e serviço, da corresponsabilidade dos participantes e da aprimoração desta habilidade de gestão em profissionais que atuam nas lideranças.
Chemical, biological, and pharmacological evaluation of the aqueous extract of Ilex paraguariensis, St. Hill. (Aquifoliaceae)
Authors: Santos Andressa Flores , Schiefer Elberth Manfron , Surek Mônica , Martins Cleverson Antônio Ferreira , Worfel Paulo Roberto , Sassaki Guilherme Lanzi , Souza Lauro Mera de , Nowacki Luciana Cristina , Souza Wesley Mauricio de
Published: January 2022

This study aimed to quantify the total phenolic and flavonoid contents in the aqueous extract of Ilex paraguariensis (EIP) and investigate its antioxidant, antimicrobial, antiulcerogenic, and antidepressant properties with concomitant verification of its effects on relevant biochemical parameters using in vivo models. EIP has in its composition 236.28 ± 11.83 mg GAE/g of total phenolics and 44.07 ± 5.56 mg QE/g of total flavonoids, corroborating its antioxidant activity. Antimicrobial assays against gram-positive (Staphylococcus aureus and Enterococcus faecalis) and gram-negative bacteria (Escherichia coli e Pseudomonas aeruginosa) showed a promising activity of EIP. The EIP administered at 500 and 1000 mg/kg doses prevented the development of gastric ulcers induced in rats following immobilization at 4 °C, however, in the ethanol-induced ulcers no significant effects were observed up to a dose of 1000 mg/kg. Gastric secretion and total acidity index in pylorus-ligated rats were reduced after treatment with EIP, and the pH did not change significantly compared to the control in the tested model. Administration of EIP to mice (250, 500, and 1000 mg/kg) significantly altered the barbiturate-induced sleep time and results of the tail suspension and forced swim test. Repeated doses of EIP did not significantly alter the evaluated biochemical markers (blood glucose, urea, creatinine, triglycerides, and total cholesterol). The results indicate that EIP may relieve gastrointestinal disorders by reducing acid secretion and decreasing immobility time in mice, suggesting an antidepressant effect. Notably, administration of multiple doses of EIP was considered preliminarily safe.
Setting the baseline for the dynamics of siphonophores and hydromedusae in Oslofjorden
Authors: Martell L , Selsø K , Titelman J , Hosia A
Published: January 2022

Knowledge of the spatio-temporal dynamics of hydromedusae and siphonophores is scarce despite their key role as predators. In the temperate inlet of Oslofjorden, studies dealing with these organisms are limited to a few reports from the 1960s on the relationship between selected species and environmental conditions of the inner fjord, but comprehensive assessments of the horizontal, vertical and seasonal variation of the pelagic hydrozoan community are lacking. In this contribution, the quantitative composition of pelagic hydrozoans in Oslofjorden was surveyed using 2 separate sampling designs: one providing a snapshot of the horizontal variation along the inner-outer fjord axis and the other assessing horizontal, seasonal and vertical changes over a yearly cycle. In total, 27 hydrozoan taxa were recorded. Hydrozoan assemblages were structured horizontally, vertically and seasonally, but patterns in the inner-outer axis were evident only when depth and seasonal variation were excluded from the analysis. A distinct assemblage of holoplanktonic hydromedusae inhabited deep (>100 m) waters regardless of season and position in the fjord. Seasonal shifts in species composition and abundance occurred sequentially, with meroplanktonic hydromedusae increasing in numbers from spring to summer and resulting in large aggregations of the medusa-budding speciesRathkea octopunctata,Stauridiosarsia gemmiferaandLizzia blondinain late summer and early autumn. No support was found for previous claims stating that the abundance of the common speciesAglantha digitale,Lensia conoideaandR. octopunctataincreases towards the inner-fjord. This work provides the first baseline data set against which potential changes in gelatinous zooplankton in the region can be contrasted.
Index Seminum 2022
Authors:   Univerzita Pavla Jozefa Šafárika v Košiciach, Mártonfiová Lenka
Published: January 2022

The Index Seminum 2022 of the Botanical Garden of the Pavol Jozef Šafárik University contains a list of 246 seed samples offered for the international exchange among botanical gardens on the world. It includes seeds collected from the wild plants in natural localities of Slovakia with a detailed description of the localities with coordinates and date of collection (99 samples) and seeds of plants grown in the Botanical Garden (12 samples) and seeds from Exposition of the Tatra Mountain Nature of the State Forests of Tatra National Park, Tatranská Lomnica (58 samples) as well as 77 seed samples from Hrádocké Arboretum of the Secondary Forestry School of Jozef Dekret Matejovie in Liptovský Hrádok. The index includes a desiderata table that can be used when ordering seeds.
IRA
Authors:   Instituto Nacional de Salud
Published: January 2022

La infección respiratoria aguda (IRA), incluye un conjunto de enfermedades que afectan el sistema respiratorio, pueden ser causadas por microorganismos virales, bacterianos y otros, con una evolución menor a 15 días.
Leptospirosis
Authors:   Instituto Nacional de Salud
Published: January 2022

​Es una enfermedad zoonótica bacteriana. Corresponde a una enfermedad febril producida por la Leptospira interrogans, una bacteria del orden Spirochaetales, de la familia Leptospiraceae, que afecta a humanos y un amplio rango de animales, incluyendo a mamíferos, aves, anfibios, y reptiles. Los principales síntomas en la mayoría de los casos son fiebre, cefalea, dolores musculares, articulares y óseos, ictericia, insuficiencia renal, hemorragias y afectación de las meninges.
Hepatitis A
Authors:   Instituto Nacional de Salud
Published: January 2022

Es una enfermedad causada por el virus de la hepatitis A (VHA). Se transmite principalmente cuando una persona no infectada (y no vacunada) come o bebe algo contaminado por heces de una per­sona infectada.
Epic, Tragic, Dramatic Theatre and the Brechtian Project
Authors: Taxidou Olga
Published: January 2022

This chapter questions the notion that Brecht’s Epic theatre is constructed solely in opposition to the Greek model of tragedy. In line with more recent and nuanced readings of the relationships between tragedy and epic, it presents Brecht’s attacks on what he perceived as Greek tragedy, through his well-documented mis-readings of Aristotelianism, as part of the modernist attempt to reclaim epic as a potentially radical form (Eisenstein), at once popular (oral, medieval etc) and modernist (montage, non-linear, stylised). Brecht’s project in this context is read as parallel to recent attempts to reclaim the epic tradition for performance. Through the work of Walter Benjamin on Brecht parallels are drawn between the Sage, the Rhapsode and the Epic Performer. Again, as throughout this book, Plato appears as a performance theorist rather than Aristotle. Through a fantastic dialogue between Brecht’s Epic Mothers and tragedy’s consummate mother, Medea, parallels are drawn between the tragic and the epic protagonist, and between the categories of tragic, epic, dramatic and post-dramatic theatre, creating a genealogy for the notion of post-dramatic theatre in Greek tragedy itself. These ideas come together in a close reading of another epic/tragic anti-mother, Antigone, in Brecht’s first of his famous models of epic theatre, The Antigone-Model.
Introduction
Authors: Högberg Elsa
Published: January 2022

This book traces modern intimacy back to the first decades of the twentieth century, and shows that modernism played a crucial role in its emergence. Intimacy, in its first two dictionary definitions – ‘1.a. The state of being personally intimate; intimate friendship or acquaintance; familiar intercourse; close familiarity; an instance of this. b. ...
Stories of O: Modernism and Female Pleasure
Authors: Frost Laura
Published: January 2022

While Chapter 1 explores intersections between eroticism and intimacy, this chapter decouples them by considering early twentieth-century advocates of female sexual pleasure in light of historical and present-day efforts to illuminate the mechanisms of female sexuality, and specifically orgasm. Examining formulations about female orgasm in the work of Mabel Dodge Luhan and D. H. Lawrence while also touching on writings by Marie Stopes, Virginia Woolf, Anaïs Nin and James Joyce, it highlights an aesthetic tendency to depict the female climax as ‘an elusive, boundless quality […] that gestures both to and beyond the phenomenon of pleasure or desire’, an introspective and intimate mode of figuration which made female orgasm susceptible to social and biopolitical ‘orgasmic discipline’. The chapter relates Luhan’s and Lawrence’s increasingly reactionary conceptions of female pleasure to Luhan’s interest in psychoanalysis, to both writers’ growing fascination with primitivist spirituality in the Taos art colony, and to the historical backdrop of women’s increased emancipation – particularly the late nineteenth- and early twentieth-century transformation of intimacy by which women could eventually exercise reproductive freedom.
The Intimacies of the Modernist Diary
Authors: Marcus Laura
Published: January 2022

This chapter considers the intimate contents and functions of the diaries kept by a group of modern writers in the 1930s, including David Gascoyne, Antonia White and Anaïs Nin. Gascoyne and Nin not only published fragments from their diaries in the 1930s but also exchanged their diary-writing between themselves, a practice that raises central questions about the diary as a private or public document. For Nin, the diary was something secret and hidden, as well as the repository of secrets, but it also had a public face for her: here the ‘intimacy of the diary’ (in Nin’s phrase) is rendered as an ‘extimacy’. Gascoyne was also closely connected to Antonia White in this period: her diary-writing, like Gascoyne’s and Nin’s, became a way of sustaining writing when fiction writing became blocked. Moreover, as with Gascoyne and Nin, her diary-writing became bound up with her psychoanalysis. Situating this archive in relation to the charged historical conditions of the 1930s, with their pressure on the writer’s capacity to separate interiority and exteriority, public and private, this chapter looks at the relationships between the dailiness of diary-keeping and of full psychoanalysis, and at the journal as a mode of writing and as self-analysis.
‘Je me trouve très sympathique’: Dada Intimacies
Authors: Hentea Marius
Published: January 2022

This chapter continues the exploration of avant-garde intimacy in attending to Dada manifestos, sound poetry and intimate interactions with the audience of the cabaret performance. It examines a particular mode of intimacy inspiring the movement’s artistic and political ambitions: ‘Dada sought to pave the way for the individual to understand the intimate within him- or herself, the spontaneous nature of one’s deeply held being, what is “most inner” – an intimacy […] pertaining to “one’s inmost self”’. Anticipating the modern form of intimacy described by Anthony Giddens as ‘emotional communication, […] in a context of interpersonal equality’, this utopian quest for self-intimacy, the chapter argues, was a core incentive for Dada’s aim to uproot bourgeois intimacies structured around family and nation as metonyms for a ‘home’ to be defended through war. Hentea shows how the intimacies cultivated by Dada’s performances served its internationalist, anti-war politics in severing links between language, culture and nation. To this end, the chapter traces Dada sound poetry’s public materialisations of ‘the very intimacy of speaking’ as manifest in its simultaneous multilingualism, intonations of the word ‘Dada’, and in Hugo Ball’s injunction: ‘We must return to the innermost alchemy of the word.’
Pepper Potts and Gwen Stacy: Recuperating the Superhero Girlfriend
Authors: Kent Miriam
Published: January 2022

This chapter further complexifies understandings of superhero girlfriends as being inherently limiting and highlights the potential for disruption within such characters. Pepper Potts of the Iron Man films (2008–2 013) and Gwen Stacy in the rebooted The Amazing Spider-Man (2012) are positioned as figures who complicate notions of empowered femininity within a generic framework that heavily draws from images of feminine victimisation. Significantly, Pepper and Gwen’s respective characterisations as quirky, loveable and resourceful ties into contemporary postfeminist notions of empowered femininity while reaching back to a model of quick-witted and fast-talking female characters that proliferated in the Classic Hollywood era, thereby complexifying the temporal location and cultural meaning of these characters. Whereas Pepper’s role can be linked to issues of working womanhood and postfeminist notions of ‘having it all,’ analysis of Gwen’s characterisation in The Amazing Spider-Man, and subsequent death in The Amazing Spider-Man 2 (2014), illustrate the negotiation of meanings when considering the superhero girlfriend’s adaptation from comic to screen.
Playing Superheroine: Feminine Subjectivity and (Postfeminist) Masquerade
Authors: Kent Miriam
Published: January 2022

This chapter provides an interrogation of the relevant notions of postfeminist masquerade with regards to Marvel superheroines, a widely-occurring narrative phenomenon that is also inflected by contemporary postfeminist practices and a mode of representation that has noticeably proliferated in these texts. Building on existing scholarship, the chapter examines the notion of the superheroine undercover, a tradition that reaches back to foundational popular feminist texts such as Charlie’s Angels (ABC, 1976–1981) and questions the implications of this tradition in the context of contemporary superheroic feminine identity. Taking account of the constructed qualities of femininity, contemporary superheroines are often introduced in disguise with the film’s narrative positioning them as ordinary civilian women before divulging their heroism. This narrative turn occupies a specific ideological role relating to postfeminist culture. This concept is explored using The Avengers’ (2012) Natasha Romanoff and expanded on in a discussion of identity crisis in the superheroine Captain Marvel.
Mad With Power: Female Villainy in Marvel Films
Authors: Kent Miriam
Published: January 2022

This chapter takes as its focus another rarely examined subject—Marvel’s villainesses and evil women. It examines how and why comic book notions of feminine villainy are appropriated and exaggerated to shape a version of the Marvel villainess as aberrant and culturally abject. Keeping in mind existing debates about the gendered meaning of evil, characters such as the evil Jean Grey and snake-woman Viper of the X-Men films, and Hela in Thor: Ragnarok (2017) are historically contextualised. In these, fissures in the discourses of postfeminism—so often engaged with the empowering qualities of feminine heterosexuality—become more disjointed when considering the denigration of female sexual assertion present in these portrayals. Such representations signal postfeminist culture’s complex relationship with issues of feminine sexuality, linking also to themes of mental distress and the toxicity of the abject female body. These narratives amplify the oppressive tendencies of such discourses when considering both the comics on which they are based and their ultimate outcomes, which usually involve narrative punishment such as death, for the villainess. These characters indicate the ways in which discourses of sexual liberation and pleasure are still highly regulated within postfeminist culture.
Mutants, Cyborgs and Femininity Unfixed? Addressing the Gendered Bodies of Mystique and Nebula
Authors: Kent Miriam
Published: January 2022

Though Marvel superhero films often display a need to maintain gender rigidity, two interesting cases are the mutant shapeshifter Mystique, who appears in the X-Men films, and the female cyborg Nebula of the Guardians of the Galaxy films. This chapter addresses the potential for queer readings of these characters, while also examining how they are placed within postfeminist boundaries. The simultaneous queering and de-queering of Mystique that occurs throughout the X-Men films is a notable paradox. Meanwhile, Nebula can be read in terms of the radical politics of the gendered cyborg, especially concerning subjectivity and family. These characters pose excellent case studies for the subject of the posthuman (but still gendered) body due to the representation of their bodies as explicitly pliable and questioning hegemonic gender norms. Both characters have an alien appearance, harnessing the generic potential of the science fiction-superhero hybrid genre that more recent superhero films make use of since the initial success of 2014’s Guardians of the Galaxy.
Afterword: Some Concluding Remarks on Marvel Women … Thus Far!
Authors: Kent Miriam
Published: January 2022

The chapter recaps the ways in which postfeminist culture shapes understandings of women’s empowerment through the women portrayed in Marvel superhero films. Looking ahead, the book concludes by remarking on current politics and their relationship to the future of the Marvel film adaptation. Further avenues of investigation with particular reference to issues of reception and quality as well as the current state of superheroines on the small screen are also considered. The conclusion draws attention to Marvel films as worthwhile objects of interrogation, representing issues of gender representation that are still prevalent in Western media culture. The overarching argument regarding the heterogeneous but often problematic representations of Marvel women is reiterated, while hope for the future of both comics and film in using the potential of the superhero genre to validate the existence of marginalised and disempowered peoples is expressed.
Introduction
Authors: Hagemann Hannah-Lena
Published: January 2022

The Introduction introduces the book’s underlying premises and main arguments, making a case for the study of ‘literary’ before ‘historical’ Khārijism. The chapter addresses the main challenges involved in studying early Islamic historiography and especially Khārijite history and then briefly summarises the literary approach adopted in this book that is meant to circumvent some of these challenges. It outlines the narrative analysis that is the focus of the subsequent chapters and illustrates why accounts of Khārijite history should not necessarily be read as hard facts, but rather as contributions to a discourse and thus as lines of arguments. The chapter also surveys previous scholarly engagements with Khārijism, almost all of which are concerned with reconstructing Khārijite history, and offers an initial discussion of the source material upon which the following analysis is based.
Novels of Comfort: Woolf, Winnicott and the Work of Consolation
Authors: Pieters Jürgen
Published: January 2022

The bibliotherapeutic publication that is central to this chapter is Katharine Smyth’s All the Lives we ever Lived, a touching memoir of her father’s illness in which the reading of Virginia Woolf’s To the Lighthouse provides the necessary consolation. The topic of literature’s consolatory powers is related in this chapter to Donald Winnicott’s analyses of ‘comforters’, what the British pyschoanalist labels ‘transitional objects’. The chapter also engages in a discussion of what David James calls ‘discrepant solace’.
Almost Wild, But Not Quite: The Indexical and the Fantastic Animal Other in China-Co-Produced (Eco)Cinema
Authors: Wang Yiman
Published: January 2022

This chapter studies two recent Chinese co-productions, Born in China (2016) and Wolf Totem (2015), which foreground the construction of the indexical and the fantastic wildlife in the very process of renegotiating the parameters of Chinese cinema. Navigating multilayered boundaries between ethnicities, species, and media industries, I analyse how the two films construct and address the tension between and intertwinement of the indexical and the fantastic wildlife. I describe the films’ de-anthropocentric impulse, articulated through technological mediation, as almost wild, but not quite. More specifically, I argue that Wolf Totem features ‘cultivated wildness’, while Born in China depends on ‘intercepted wildness’. Both bespeak fantastic ecocinematic consciousness without carrying it to full fruition.
The Abode of Sedition: Resistance, Repression and Revolution in Sasun, 1891–1904
Authors: Altıntaş Toygun
Published: January 2022

This article will investigate the transformation of Sasun, a remote mountainous region inhabited by Armenian and Muslim peasants as well as Kurdish pastoralists, into a zone of contention between the Hamidian regime and the Armenian revolutionary movement. The conflict in Sasun became a cause célèbre of imperial and international significance and was followed closely by foreign journalists and diplomats, Ottoman and Russian Armenians, government officials, and Sultan Abdülhamid II himself. Using Ottoman and British archival sources as well as the official organs of the Hnchak Party and the Armenian Revolutionary Federation, the article will foreground subjects and practices of resistance and repression during this period. Doing so will allow us to trace the process by which local encounters and struggles gained imperial and international import. The article will focus on the period from 1891, when the first Hnchak revolutionary arrived in the region, to 1904, when the Hamidian regime deployed a large military force for the second time to destroy the revolutionary presence and bring the region’s Armenians to heel. It will examine revolutionary tactics and strategies of recruitment, propaganda, and utilization of violence. It will also shed light on Hamidian practices of cooptation, exclusion, criminalization, and collective punishment.
Afterword
Authors: Zürcher Erik Jan
Published: January 2022

Age of Rogues is a collection of case studies and, as in any such collection, the cases selected are intended as so many tools to detect recurrent patterns; to uncover larger historical developments through comparison, even if that comparison is implicit rather than explicit. The larger questions that suggest themselves in the context of this volume, therefore, obviously are: is there an overarching category that can usefully be called ‘rogues’? And, is there something that can be meaningfully designated an era in which they were especially prevalent or played an especially important role – an ‘age of rogues’?...
‘To Return Home with… Satisfaction and Pleasure’: Home and Family Networks
Authors: Davy Daniel
Published: January 2022

Chapter One discusses the British and Irish origins of gold seekers, their paths to Australasia and gold seekers’ personal connections to communities and families in Britain and Ireland. The Chapter argues that the Otago goldfields population was heavily influenced by migration streams to the Australian colonies which later converged on the Victorian goldfields, stressing the role of kinship and community networks in facilitating and directing migration. The Chapter further shows how these kinship bonds were transplanted in Otago, as well as the degree to which individuals retained connections to loved ones in Britain or Ireland through the exchange of correspondence. By analysing migrant correspondence, the Chapter frames gold seeker identities within communities at home and the degree to which these relationships were maintained after overseas migration.
An Overview of Banietemad’s Career and Films
Authors: Ghorbankarimi Maryam
Published: January 2022

The introduction offers an overview of Banietemad’s life and works. It also addresses each chapter individually to highlight the main argument and content of each chapter as well as demonstrating their connection with the overall aims and scope of the book.
From Black Comedies to Social Realism: Rakhshan Banietemad’s Early Feature Films
Authors: Zahedi Farshad
Published: January 2022

This chapter offers an analytical study of Banietemad’s first films, none of which has previously been addressed in detail. Zahedi contextualizes the historical, political, and social factors that led to the birth of a social genre in Iran, and examines the ways in which Banietemad, as an auteur, negotiated the systematic constraints and censorship she faced in her early career with efficient strategies in selecting and staging apparently non-problematic narratives.
Coda: The Resurrection of Whiteness
Authors: Murray Hannah Lauren
Published: January 2022

Drawing together discussions of White citizenship throughout the book, the Coda examines the detachment between civic ideals and the individual White male in Herman Melville’s The Confidence-Man. The eponymous trickster’s vocal mimicry across racial identities, akin to the spiritualist medium, fractures the self-contained self-made White male citizen, while at the same time enacting the ultimate social freedom to transgress those borders. The book closes with a turn to liminal Whiteness in the contemporary moment. The early US imagination of becoming less than White continues in the language of oppression, replacement, and genocide that frames White supremacist ethno-nationalist anxieties of racial mobility in the contemporary United States.
The Highland Stories
Authors: Cook Daniel
Published: January 2022

How do we read ‘The Highland Widow’? Broadly structured like a traditional oral tale, the text has distinct descriptions, rhetorical repetition and a charismatic narrator. But the modern-minded narrator freely mixes third-party paraphrase with reported speech (itself paraphrased from the widow’s decades-old interactions), casually alludes to cut or condensed exchanges, and subtly interposes her own critical assumptions. The text also looks bookish. It is divided into chapters. There are verbal glosses on Gaelic words in a handful of footnotes. Who are they for? In ‘The Two Drovers’, Scott again mixes elements of popular storytelling, including the motifs, vocabularies and codes of crime writing, the picaresque, the picturesque, Gaelic poetry, cultural Jacobitism and more. The story lacks heroes, but it still explores heroism. It is not a supernatural tale, but it features the Highland figure of the spaewife, a female fortune teller. Read as metafiction, within the context of the curated collection Chronicles of the Canongate, ‘The Two Drovers’ and ‘The Highland Widow’ challenge the authority of a narrator.
Afterword: The Modern Scottish Short Story
Authors: Cook Daniel
Published: January 2022

Abstract and Keywords to be supplied.
In a Shakespearean Key
Authors: Svich Caridad
Published: January 2022

This chapter reflects on the author’s first encounters with Shakespeare on the page, and how identity formations occur between and among languages for a reader and a writer at an early stage in their career. The piece circles around ideas of what it means to be Latinx in US culture, how portals of the imaginary may be unlocked in unexpected ways and how writing is essentially an act of freedom. The author’s own feminist interventions into Shakespeare–12 Ophelias, Perdita Garcia, The Breath of Stars, and more—are referenced as well as her experience as a translator and adaptor of theatrical material.
Diálogo: On Translation and Adaptation
Authors: Godinez Henry , Valenzuela José Luis , Gatta Carla Della
Published: January 2022

José Luis Valenzuela and Henry Godinez draw from their extensive experience as actors, directors and theatre professors to discuss how translation and adaptation have factored into their journeys with Shakespeare. While both artists are firmly grounded in US theatre-making practices, both of them were introduced to Shakespeare through European aesthetics, be it a workshop with Patrick Stewart or directing work in Europe. Both address the need for Latinx stories and new approaches to storytelling as part of the complicated relationship to the western canon. They discuss the pleasure of working with Shakespeare’s dialogue and their careers that span a range of classics from the Spanish Golden Age, Lorca, and Shakespeare, as well as their partnership with living playwrights, and how those processes differ.
Diálogo: On Making Shakespeare Relevant to Latinx Communities
Authors: González José Cruz , Lozano David
Published: January 2022

In this conversation, directors and community-focused artists José Cruz González and David Lozano discuss the varied ways they have appropriated Shakespeare in community settings. From community-engagement projects featuring lost Native American languages (the Chumash culture and Samala language of González’s The Winter’s Tale adaptation, Invierno) to physical theatre riffs off The Tempest and The Merchant of Venice, both González and Lozano demonstrate how Shakespeare can be remixed to become relevant to Latinx audiences today. Although the productions they discuss are distinct, they all share the same goal: to be relevant to Latinx audiences who might not otherwise see themselves represented in a traditional production of one of Shakespeare’s plays. They each discuss their involvement with distinct productions and adaptations of Romeo and Juliet. González addresses his Theatre for Young Audiences (TYA) Shakespearean appropriation, Forever Poppy.
Willful Invisibility: Translating Shakespeare’s
Authors: Solis Octavio
Published: January 2022

In this chapter, Octavio Solis writes about his experience in “translating” Edward III for the Play on! project at the Oregon Shakespeare Festival. The chapter addresses his difficulty in finding his way into the text, how the rich archaic idiom seemed at once seductive and remote, and how his particular background as a Mexican-American with English as his acquired tongue helped me find my way in. Solis points out how his love of crossword puzzles enabled him to break the code of Shakespeare’s language. The use of meter in his plays is paramount in understanding how he invented countless words and phrases to suit not only the sense of character intention, but also to satisfy the metrical demands of the poetry. But he was also apt in finding ways to “cheat the beat” and defy his own rigor in following the meter. In the end, Solis felt like he had slipped Shakespeare’s writing glove on his hand, and began to understand how he made decisions every step along the way.
Sosyal Ağlar Büyük Veriden Nasıl Yararlanır: Facebook ve Twitter
Authors: SUVAY EKER Halime
Published: January 2022

İnternet teknolojisinin gelişmesiyle günlük yaşantımızda bilgisayar, tablet ve cep telefonlarının kullanımında önemli bir artış meydana gelmiştir. Web 2.0 teknolojisinin ortaya çıkışı ile bilgiye yalnızca okumak için erişen kullanıcılar içeriğe katkıda bulunmaya başlamıştır. Özellikle sosyal ağlar kullanıcıların içerik üretmelerini ve paylaşmalarını sağlaması açısından önemli bir yere sahiptir. Facebook, kullanıcıların birbirleriyle iletişim kurmalarını ve bilgi paylaşımında bulunmalarını sağlayan, 2004 yılında kurulmuş, dünyanın en büyük sosyal ağıdır. 2006 yılında kurulan Twitter ise, “mikro web günlüğü” olarak başlatılmıştır ve günümüzde en çok kullanılan sosyal ağlardan birini oluşturmaktadır. Milyonlarca kullanıcısı olan Facebook ve Twitter’ın büyük veriye sahip olduğu ve bu verilerden yararlandığı bilinmektedir. Bu makalede, Facebook ve Twitter’ın sahip olduğu büyük veriyi nasıl elde ettiğini ve hangi amaçla kullandığını ortaya çıkarmak amaçlanmıştır. Bu doğrultuda literatür taraması yöntemiyle bu konu ile ilgili daha önceki çalışmalar Google Akademik, TR Dizin, WoS, Scopus ve IEEE Xplore veritabanları üzerinden araştırılmıştır. Özellikle Facebook ve Twitter'ın verileri kullanılarak yapılan çalışmalar seçilmiş ve incelenmiştir. İncelenen çalışmalar sonucunda, Facebook ve Twitter kullanıcılarının bu ağlara yükledikleri her bir içeriğin (cinsiyet bilgisi, eğitim bilgisi, konum bilgisi, beğeniler, yorumlar, atılan tweetler vb.) büyük veriyi oluşturduğu tespit edilmiştir. Farklı birçok yöntem kullanılarak analiz edilen büyük verinin genel olarak işletmelerin markalarına müşteri bulmasında, insanların belli bir konu hakkında tutumlarının ne olduğunun ortaya çıkarılmasında veya siyasal seçimlerin sonucunu etkilemek için seçim stratejilerinde kullanıldığı saptanmıştır.
The Pengalaman Aktivitas Spiritual pada Orang dengan HIV/AIDS (ODHA) dalam Menjalani Proses Penyakitnya
Authors: Edison Chiyar , Setyowati Setyowati , Waluyo Agung
Published: January 2022

Kesejahteraan spiritual merupakan domain yang mempengaruhi luaran dari terapi antiretroviral pada ODHA. Namun, saat ini kebutuhan spiritual pada ODHA masih belum optimal terpenuhi dalam tatanan layanan kesehatan. Oleh karena itu, penting diketahui pengalaman spiritual pada ODHA untuk diketahui gambaran kebutuhannya. Penelitian fenomenologi deskriptif ini bertujuan untuk mengeksplorasi pengalaman spiritual ODHA selama menjalani proses penyakitnya dengan melibatkan lima partisipan dalam wawancara mendalam. Analisis konten tematik menghasilkan lima tema besar, yaitu:  (1) Mendapatkan hidayah, dekat dengan agama, lebih takut dengan dosa dan lebih rajin sholat dan membaca kitab suci; (2) Pasrah dan menerima penyakitnya karena  ini adalah teguran, cobaan dan kekuasaan Allah; (3) Dukungan ibu yaitu mengajak ke pengajian dan diingatkan untuk dzikir; (4) Mengalami kesedihan, syok, menyalahkan orang lain sehingga ingin mengakhiri hidup dan menghindari orang lain; (5) Harapan partisipan adalah sehat di dunia, dan beruntung di akhirat. Studi ini merekomendasikan penelitian lebih lanjut secara kuantitatif serta perlunya pengkajian spiritualitas pada ODHA dalam praktik asuhan keperawatan.
FEATURES OF FORMATION OF INNOVATIVE TOOLS OF MODERN MARKETING IN THE CONDITIONS OF TRANSFORMATION OF DIGITAL ECONOMY
Authors: Bodnaruk Oksana
Published: January 2022

The purpose of the article – is to identify and analyze the current trends of
innovative marketing communication technologies and their impact on the business
and potential consumer in the context of digital transformation.
The research methodology of the study is the application of methods of analysis,
synthesis, comparison, generalization, prediction, as well as the use of a systemic
approach.
The scientific novelty is due to the fact that the article considers modern trends
in the development of innovative marketing, as well as the formation of marketing
communications in a digital environment, their difference from traditional channels.
It is proposed to use the most modern and promising digital marketing tools.
Conclusions. As a result of the study, it was established that digital technologies
that form marketing tools have the potential to ensure the efficiency of marketing
activities in the digital business environment, affect the growth of the speed of these actions, the growth of scale, and the adaptability of business processes of enterprises. It has been proven that the use of digital technologies in marketing
allows us to provide constant feedback and develop individual offers, increase
consumer interest in marketing programs, which will radically change marketing
results and increase business profitability. It is justified that with the right
combination of innovative marketing tools, you can create a marketing strategy
that will constantly develop, which will deepen multi-channel communication with
both the consumer and partners, which in turn will contribute to the implementation
of the concept of sustainable marketing.
Key words: digitalization, marketing tools, digital economy, business, marketing
efficiency.
Non-Coding RNAs and Brain Tumors: Insights Into Their Roles in Apoptosis
Authors: Tamtaji Omid Reza , Derakhshan Maryam , Rashidi Noshabad Fatemeh Zahra , Razaviyan Javad , Hadavi Razie , Jafarpour Hamed , Jafari Ameneh , Rajabi Ali , Hamblin Michael R. , Mahabady Mahmood Khaksary , Taghizadieh Mohammad , Mirzaei Hamed
Published: January 2022

A major terrifying ailment afflicting the humans throughout the world is brain tumor, which causes a lot of mortality among pediatric and adult solid tumors. Several major barriers to the treatment and diagnosis of the brain tumors are the specific micro-environmental and cell-intrinsic features of neural tissues. Absence of the nutrients and hypoxia trigger the cells’ mortality in the core of the tumors of humans’ brains: however, type of the cells’ mortality, including apoptosis or necrosis, has been not found obviously. Current studies have emphasized the non-coding RNAs (ncRNAs) since their crucial impacts on carcinogenesis have been discovered. Several investigations suggest the essential contribution of such molecules in the development of brain tumors and the respective roles in apoptosis. Herein, we summarize the apoptosis-related non-coding RNAs in brain tumors.
MicroRNA-223-3p Protect Against Radiation-Induced Cardiac Toxicity by Alleviating Myocardial Oxidative Stress and Programmed Cell Death via Targeting the AMPK Pathway
Authors: Zhang Dao-ming , Deng Jun-jian , Wu Yao-gui , Tang Tian , Xiong Lin , Zheng Yong-fa , Xu Xi-ming
Published: January 2022

Objectives: Radiotherapy improves the survival rate of cancer patients, yet it also involves some inevitable complications. Radiation-induced heart disease (RIHD) is one of the most serious complications, especially the radiotherapy of thoracic tumors, which is characterized by cardiac oxidative stress disorder and programmed cell death. At present, there is no effective treatment strategy for RIHD; in addition, it cannot be reversed when it progresses. This study aims to explore the role and potential mechanism of microRNA-223-3p (miR-223-3p) in RIHD.

Methods: Mice were injected with miR-223-3p mimic, inhibitor, or their respective controls in the tail vein and received a single dose of 20 Gy whole-heart irradiation (WHI) for 16 weeks after 3 days to construct a RIHD mouse model. To inhibit adenosine monophosphate activated protein kinase (AMPK) or phosphodiesterase 4D (PDE4D), compound C (CompC) and AAV9-shPDE4D were used.

Results: WHI treatment significantly inhibited the expression of miR-223-3p in the hearts; furthermore, the levels of miR-223-3p decreased in a radiation time-dependent manner. miR-223-3p mimic significantly relieved, while miR-223-3p inhibitor aggravated apoptosis, oxidative damage, and cardiac dysfunction in RIHD mice. In addition, we found that miR-223-3p mimic improves WHI-induced myocardial injury by activating AMPK and that the inhibition of AMPK by CompC completely blocks these protective effects of miR-223-3p mimic. Further studies found that miR-223-3p lowers the protein levels of PDE4D and inhibiting PDE4D by AAV9-shPDE4D blocks the WHI-induced myocardial injury mediated by miR-223-3p inhibitor.

Conclusion: miR-223-3p ameliorates WHI-induced RIHD through anti-oxidant and anti-programmed cell death mechanisms via activating AMPK by PDE4D regulation. miR-223-3p mimic exhibits potential value in the treatment of RIHD.
Multi-Functional Hypercrosslinked Polystyrene as High-Performance Adsorbents for Artificial Liver Blood Purification
Authors: Liu Yunhong , Peng Xinyan
Published: January 2022

In artificial liver blood purification system, highly efficient removal of multiple toxic metabolites from whole blood by hemoperfusion still remains a challenge in the clinical field, due to the limited unspecific absorptive capacity and low biocompatibility of adsorbents. In this work, a new pyridinyl-modified hypercrosslinked polystyrene (HCP) adsorbent, named HCP(St-DVB-VP), was constructed directly through a Friedel-Crafts post-crosslinking reaction using a small-molecule crosslinking agent for the first time. The preparation method provides in this study can avert the problem posed by the use of the toxic carcinogenic chloromethyl ether reagent in the traditional HCP resin synthesis process. The results indicated that HCP(St-DVB-VP) had a highly porous structure with a specific surface area of 761 m2 g−1. Notably, the adsorbent demonstrated excellent adsorptive properties towards both protein-bound toxins (bilirubin) and medium- and large-sized molecular toxins (PTH, IL-6) in vitro experiments simultaneously. More importantly, the obtained adsorbent showed acceptable hemocompatibility. Taken together, the low-cost and ecofriendly fabrication method, broad-spectrum adsorption performance and hemocompatibility makes the HCP(St-DVB-VP) promising for whole blood perfusion in artificial liver blood purification in clinical practice.
Efficient Green Quasi-Two-Dimensional Perovskite Light-Emitting Diodes Based on Mix-Interlayer
Authors: Wang Zirong , Meng Fanyuan , Feng Qi , Shi Shengxuan , Qiu Langwen , Sun Guanwei , Chen Zhao , Zeng Qingguang , Zhu Weiguo , Su Shi-Jian
Published: January 2022

Recently, quasi-two-dimensional (Q-2D) perovskites have received much attention due to their excellent photophysical properties. Phase compositions in Q-2D perovskites have obvious effect on the device performance. Here, efficient green perovskite light-emitting diodes (PeLEDs) were fabricated by employing o-fluorophenylethylammonium bromide (o-F-PEABr) and 2-aminoethanol hydrobromide (EOABr) as the mix-interlayer ligands. Phase compositions are rationally optimized through composition and interlayer engineering. Meanwhile, non-radiative recombination is greatly suppressed by the introduction of mix-interlayer ligands. Thus, green PeLEDs with a peak photoluminescence quantum yield (PLQY) of 81.4%, a narrow full width at half maximum (FWHM) of 19 nm, a maximum current efficiency (CE) of 27.7 cd/A, and a maximum external quantum efficiency (EQE) of 10.4% were realized. The results are expected to offer a feasible method to realize high-efficiency PeLEDs.
Prevalence of Sarcoidosis-Associated Pulmonary Hypertension: A Systematic Review and Meta-Analysis
Authors: Zhang Shijie , Tong Xiang , Zhang Tianli , Wang Dongguang , Liu Sitong , Wang Lian , Fan Hong
Published: January 2022

Background

Sarcoidosis-associated pulmonary hypertension (SAPH) is associated with poor prognosis, conferring up to a 10-fold increase in mortality in patients with sarcoidosis, but the actual prevalence of SAPH is unknown.

Methods

The PubMed, Embase, and Cochrane Library databases were systematically searched for epidemiological studies reporting the prevalence of SAPH up to July 2021. Two reviewers independently performed the study selection, data extraction, and quality assessment. Studies were pooled using random-effects meta-analysis.

Results

This meta-analysis included 25 high-quality studies from 12 countries, with a pooled sample of 632,368 patients with sarcoidosis. The prevalence of SAPH by transthoracic echocardiography in Europe, the United States and Asia was 18.8% [95% confidence interval (CI): 11.1–26.5%], 13.9% (95% CI: 5.4–22.4%) and 16.2% (95% CI: 7.1–25.4%) separately, and the overall pooled prevalence was 16.4% (95%CI: 12.2–20.5%). By right heart catheterization (RHC), the pooled prevalence of SAPH was 6.4% (95% CI: 3.6–9.1%) in general sarcoidosis population, and subgroup analyses showed that the prevalence of SAPH was 6.7% (95% CI: 2.4–11.0%) in Europe and 8.6% (95% CI: −4.1 to 21.3%) in the United States. Further, the prevalence of pre-capillary PH was 6.5% (95% CI: 2.9–10.2%). For the population with advanced sarcoidosis, the pooled prevalence of SAPH and pre-capillary PH by RHC was as high as 62.3% (95% CI: 46.9–77.6%) and 55.9% (95% CI: 20.1–91.7%), respectively. Finally, the pooled prevalence of SAPH in large databases with documented diagnoses (6.1%, 95% CI: 2.6–9.5%) was similar to that of RHC. Substantial heterogeneity across studies was observed for all analyses (I2 > 80%, P < 0.001).

Conclusions

The sarcoidosis population has a relatively low burden of PH, mainly pre-capillary PH. However, as the disease progresses to advanced sarcoidosis, the prevalence of SAPH increases significantly.