bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcriptional Regulation of Drought Response in Arabidopsis and Woody Plants
Authors: Yao Tao , Zhang Jin , Xie Meng , Yuan Guoliang , Tschaplinski Timothy J. , Muchero Wellington , Chen Jin-Gui
Published: January 2021

Within the context of global warming, long-living plants such as perennial woody species endure adverse conditions. Among all of the abiotic stresses, drought stress is one of the most detrimental stresses that inhibit plant growth and productivity. Plants have evolved multiple mechanisms to respond to drought stress, among which transcriptional regulation is one of the key mechanisms. In this review, we summarize recent progress on the regulation of drought response by transcription factor (TF) families, which include abscisic acid (ABA)-dependent ABA-responsive element/ABRE-binding factors (ABRE/ABF), WRKY, and Nuclear Factor Y families, as well as ABA-independent AP2/ERF and NAC families, in the model plant Arabidopsis. We also review what is known in woody species, particularly Populus, due to its importance and relevance in economic and ecological processes. We discuss opportunities for a deeper understanding of drought response in woody plants with the development of high-throughput omics analyses and advanced genome editing techniques.
Leaf Venation and Morphology Help Explain Physiological Variation in Yucca brevifolia and Hesperoyucca whipplei Across Microhabitats in the Mojave Desert, CA
Authors: Jolly Amber R. , Zailaa Joseph , Farah Ugbad , Woojuh Janty , Libifani Félicia Makaya , Arzate Darlene , Caranto Christian Alex , Correa Zayra , Cuba Jose , Calderon Josephina Diaz , Garcia Nancy , Gastelum Laura , Gutierrez Ivette , Haro Matthew , Orozco Monserrat , Pinlac Jessica Lamban , Miranda Andoni , Nava Justin , Nguyen Christina , Pedroza Edgar , Perdomo Jennyfer , Pezzini Scott , Yuen Ho , Scoffoni Christine
Published: January 2021

Different microclimates can have significant impact on the physiology of succulents that inhabit arid environments such as the Mojave Desert (California). We investigated variation in leaf physiology, morphology and anatomy of two dominant Mojave Desert monocots, Yucca brevifolia (Joshua tree) and Hesperoyucca whipplei, growing along a soil water availability gradient. Stomatal conductance (gs) and leaf thickness were recorded in the field at three different sites (north-western slope, south-eastern slope, and alluvial fan) in March of 2019. We sampled leaves from three individuals per site per species and measured in the lab relative water content at the time of gs measurements, saturated water content, cuticular conductance, leaf morphological traits (leaf area and length, leaf mass per area, % loss of thickness in the field and in dried leaves), and leaf venation. We found species varied in their gs: while Y. brevifolia showed significantly higher gs in the alluvial fan than in the slopes, H. whipplei was highest in the south-eastern slope. The differences in gs did not relate to differences in leaf water content, but rather to variation in number of veins per mm2 in H. whipplei and leaf width in Y. brevifolia. Our results indicate that H. whipplei displays a higher water conservation strategy than Y. brevifolia. We discuss these differences and trends with water availability in relation to species’ plasticity in morphology and anatomy and the ecological consequences of differences in 3-dimensional venation architecture in these two species.
Hatching Induction of Cyst Nematodes in Bare Soils Drenched With Root Exudates Under Controlled Conditions
Authors: Ngala Bruno , Mariette Nicolas , Ianszen Mélina , Dewaegeneire Pauline , Denis Marie-Christine , Porte Catherine , Piriou Christophe , Robilliard Emilie , Couetil Antoine , Nguema-Ona Eric , Yvin Jean-Claude , Gobert Virginie , Beury Amélie , Le Roux Anne-Claire , Montarry Josselin , Fournet Sylvain
Published: January 2021

Cyst nematodes account for substantial annual yield losses in crop production worldwide. Concerns over environmental and health issues due to the use of chemical nematicides mean alternative sustainable and integrated solutions are urgently required. Hatch induction of encysted eggs in the absence of host plants, i.e., ‘suicide-hatching,’ could be a sustainable alternative in reducing population densities of cyst nematodes in infested soils. Here we examinedin situhatching of encysted eggs ofGlobodera pallida,Heterodera carotae, andHeterodera schachtiiat varying soil depths, following exogenous applications of host root exudates in repeated glasshouse experiments. Cysts were retrieved 30 or 43 days post-incubation depending on the nematode species and assessed for hatching rates relative to the initial number of viable eggs per cyst. Hatching of the potato cyst nematodeG. pallidadepended on both soil moisture and effective exposure to root exudates, and to a lesser extent on exudate concentration. The carrot cyst nematodeH. carotaehad over 75% hatched induced by root exudate irrespective of the concentration, with better hatch induction at 20 cm as compared with 10 cm soil depth. Hatching of the beet cyst nematodeH. schachtiilargely depended on the soil moisture level at constant temperature, rather than the type or concentration of root exudates applied. As a conclusion, exogenously applied host root exudates may play a major role in inducingin situhatch of encysted eggs of potato and carrot cyst nematodes in the absence of host plant under favorable soil temperature/moisture conditions. To improve such strategy, the characterization of chemical profiles of the root exudate composition and field validation are currently ongoing.
Floral Color Properties of Serpentine Seep Assemblages Depend on Community Size and Species Richness
Authors: LeCroy Kathryn A. , Arceo-Gómez Gerardo , Koski Matthew H. , Morehouse Nathan I. , Ashman Tia-Lynn
Published: January 2021

Functional traits, particularly those that impact fitness, can shape the ecological and evolutionary relationships among coexisting species of the same trophic level. Thus, examining these traits and properties of their distributions (underdispersion, overdispersion) within communities can provide insights into key ecological interactions (e.g., competition, facilitation) involved in community assembly. For instance, the distribution of floral colors in a community may reflect pollinator-mediated interactions between sympatric plant species, and the phylogenetic distribution of color can inform how evolutionary contingencies can continue to shape extant community assemblages. Additionally, the abundance and species richness of the local habitat may influence the type or strength of ecological interactions among co-occurring species. To evaluate the impact of community size and species richness on mechanisms shaping the distribution of ecologically relevant traits, we examined how floral color (defined by pollinator color vision models) is distributed within co-flowering assemblages. We modeled floral reflectance spectra of 55 co-flowering species using honeybee (Apis mellifera) and syrphid fly (Eristalis tenax) visual systems to assess the distributions of flower color across 14 serpentine seep communities in California. We found that phylogenetic relatedness had little impact on the observed color assemblages. However, smaller seep communities with lower species richness were more overdispersed for flower color than larger, more species-rich communities. Results support that competitive exclusion could be a dominant process shaping the species richness of flower color in smaller-sized communities with lower species richness, but this is less detectable or overwhelmed by other processes at larger, more speciose communities.
Development and Psychometric Validation of the Music Receptivity Scale
Authors: George Mahesh , Ilavarasu Judu
Published: January 2021

A new construct, termed music receptivity, is introduced and discussed in this work. Music receptivity can be defined as a measure of the extent of internalization that an individual has, to a given piece of music, as measured at the point of listening. Through three studies, we demonstrate the psychometric properties of the construct—the Music Receptivity Scale (MRS). Exploratory factor analysis on a sample of 313 revealed good psychometric validity, with a four-factor solution (emotional experience, interest, attention, and hurdles), with a Cronbach’s alpha of 0.89, and a two-factor solution (emotion experience and attention), with a Cronbach’s alpha of 0.87. The tool also had a good test–retest reliability (r = 0.87 for a 15 day interval and r = 0.91 for 1 month interval). Overall, the tool had 20 items in the long form and 12 items in the short version. The MRS could distinguish musicians and non-musicians supporting its discriminant validity. We have also discussed the implication of the MRS in the field of music psychology.
Implicit Detection Observation in Different Features, Exposure Duration, and Delay During Change Blindness
Authors: Xiang Wang
Published: January 2021

To investigate whether implicit detection occurs uniformly during change blindness with single or combination feature stimuli, and whether implicit detection is affected by exposure duration and delay, two one-shot change detection experiments are designed. The implicit detection effect is measured by comparing the reaction times (RTs) of baseline trials, in which stimulus exhibits no change and participants report “same,” and change blindness trials, in which the stimulus exhibits a change but participants report “same.” If the RTs of blindness trials are longer than those of baseline trials, implicit detection has occurred. The strength of the implicit detection effect was measured by the difference in RTs between the baseline and change blindness trials, where the larger the difference, the stronger the implicit detection effect. In both Experiments 1 and 2, the results showed that the RTs of change blindness trials were significantly longer than those of baseline trials. Whether under set size 4, 6, or 8, the RTs of the change blindness trials were significantly longer than those in the baseline trials. In Experiment 1, the difference between the baseline trials’ RTs and change blindness trials’ RTs of the single features was significantly larger than that of the combination features. However, in Experiment 2, the difference between the baseline trials’ RTs and the change blindness trials’ RTs of single features was significantly smaller than that of the combination features. In Experiment 1a, when the exposure duration was shorter, the difference between the baseline and change blindness trials’ RTs was smaller. In Experiment 2, when the delay was longer, the difference between the two trials’ RTs was larger. These results suggest that regardless of whether the change occurs in a single or a combination of features and whether there is a long exposure duration or delay, implicit detection occurs uniformly during the change blindness period. Moreover, longer exposure durations and delays strengthen the implicit detection effect. Set sizes had no significant impact on implicit detection.
Study of Sexual Satisfaction in Different Typologies of Adherence to the Sexual Double Standard
Authors: Álvarez-Muelas Ana , Gómez-Berrocal Carmen , Sierra Juan Carlos
Published: January 2021

The sexual double standard (SDS) refers to the acceptance of different criteria to assess the same sexual behavior in men and women. To date, the few studies that have addressed the relationship between SDS and sexual satisfaction have obtained inconclusive results. In addition, no study has analyzed sexual satisfaction in people who maintain different forms of adherence to the SDS. This study establishes three SDS typologies of adherence (man-favorable, woman-favorable, egalitarian) in two areas of sexual behavior (sexual freedom and sexual shyness) to examine the predictive capacity of personal variables (age, social dominance orientation, propensity for sexual excitation/inhibition), interpersonal variables (relationship satisfaction) and social variables (gender norms about sexual behaviors) in sexual satisfaction. A sample of 1194 heterosexual adults (51.1% men, 48.8% women) aged between 18 and 87 years (M = 40.63; SD = 15.67), who had been in a relationship for more than 6 months, was evaluated. In men, the highest sexual satisfaction levels were obtained in the egalitarian typology in the sexual freedom area. In women, no significant differences were found between the typologies of adherence to the SDS. Regression models showed that relationship satisfaction was the main predictor of sexual satisfaction in all the typologies in both men and women. In addition, the predictive relationship of personal variables with sexual satisfaction varied according to gender and the SDS adherence type. The results show the importance of studying sexual satisfaction by taking into account not only the differences between men and women. Furthermore, it is essential to consider other differences between people; for example, the difference that derives from the way of psychologically internalizing attitude toward the SDS.
Parental Teaching of Reading and Spelling Across the Transition From Kindergarten to Grade 1
Authors: Silinskas Gintautas , Aunola Kaisa , Lerkkanen Marja-Kristiina , Raiziene Saule
Published: January 2021

We investigated the longitudinal links between parental teaching of reading and spelling and children’s word reading and spelling skills. Data of 244 Lithuanian parent–child dyads were analyzed, who were followed across three time points: end of kindergarten (T1;Mage= 6.88; 116 girls), beginning of Grade 1 (T2), and end of Grade 1 (T3). The children’s word reading and spelling skills were tested, and the parents answered questionnaires on the frequency with which they taught their children reading and spelling. Overall, the results showed that the parents were responsive to their children’s skill levels across the domains of reading and spelling and across time (i.e., the transition from kindergarten to Grade 1 and across Grade 1). However, differences between the domains of reading and spelling were also observed. In particular, in the domain of reading and across the transition from kindergarten to Grade 1, the parents responded to their children’s skill levels by increasing the time spent teaching children with poor word reading skills, and decreasing the teaching time for the children with good word reading skills. In contrast, as spelling skills may require more time to develop, parents maintained similar frequencies of teaching spelling across the transition to Grade 1 for all children, and only parents of good spellers taught less spelling at the end of Grade 1 than parents of children with poor and average word spelling skills.
Characterizing Treatment-Resistant Anorexia Nervosa
Authors: Smith Sarah , Woodside D. Blake
Published: January 2021

Background:The issue of treatment resistance in eating disorder care is controversial. Prior research has identified multiple failed treatment attempts as a common criterion for severe and enduring anorexia nervosa, but little is known about patients who have multiple failed treatment attempts. This study was designed to compare the clinical and demographic characteristics of eating disorder patients with multiple, incomplete inpatient admissions to those with good outcomes. Understanding if these patient populations differ at initial admissions has implications for the prediction and characterization of inpatient eating disorder treatment resistance.

Methods:This study analyzed existing data from a specialist inpatient eating disorder program at a large Canadian teaching hospital collected between 2000 and 2016. Treatment resistance was defined as two or more incomplete admissions and no complete admissions in the study period. Data were available on 37 patients who met this criteria, and 38 patients who had completed their first admission and remained well (defined as a BMI > 18.5 with no binging or purging behavior) 1 year after discharge. Variables of interest included age, weight, diagnoses, duration of illness, eating disorder psychopathology, eating disorder behavioral frequencies and depressive symptoms at the time of index inpatient admissions. Statistical analyses consisted of Mann–Whitney U tests, Chi-square tests, and a logistic regression.

Results:In our main bivariate analyses, patients with multiple incomplete admissions were characterized by more severe eating disorder psychopathology and depressive symptoms at admission as well as an increased prevalence of the binge purge subtype of anorexia nervosa. In our exploratory multivariate analyses controlling for diagnostic subtype and depressive symptoms, severity of eating disorder psychopathology did not remain significant. No statistically significant difference in body mass index (BMI) or frequencies of eating disorder behaviors were found. A trend toward a longer duration of illness did not meet statistical significance.

Conclusions:This study found that patients considered resistant to inpatient eating disorder treatment differ from those with good outcomes at initial admission. These results suggest that while treatment-resistant anorexia nervosa may be related to severe and enduring anorexia nervosa, it may also be a different concept that warrants additional research.
Risk Factors for Serious Suicide Attempts: Difference Between Older and Younger Attempters in the Emergency Department
Authors: Kim Dong Wook , Cho Seo Eun , Kang Jae Myeong , Woo Soo Kyun , Kang Seung-Gul , Yeon Byeong Kil , Cho Seong-Jin
Published: January 2021

Objective: Suicide attempts of the older adults are known to be more serious than that of the younger adults. Despite its major social impact in South Korea, the behavioral mechanism of serious suicide attempt (SSA) in old people remains to be elucidated. Thus, we investigated the risk factors for SSA in older and younger suicide attempters in the emergency department.

Methods: Demographic data, clinical information, and the level of seriousness of suicide with Risk Rescue Rating Scale were compared between older (age ≥65) and younger (age <65) adults who visited the emergency department for a suicide attempt. Regression analyses were performed to identify the risk factors for SSA in these two groups.

Results: Among 370 patients, 37 were older adults (10%; aged 74.41 ± 6.78), more likely to have another medical disease (p < 0.001), and a higher suicide completion rate (16.2 vs. 5.4%, p = 0.023). In the younger group, old age (B = 0.090, p < 0.001), male sex (B = −0.038, p = 0.019), and impression of schizophrenia (B = 0.074, p = 0.027) were associated with a higher risk-rescue ratio and interpersonal stress condition was associated with a lower risk-rescue ratio (B = −0.045, p = 0.006). In the older group, however, no variables were included significant in the regression model for the Risk Rescue Rating Scale.

Conclusions: Demographic and clinical factors such as old age, male sex, interpersonal stress, and impression of schizophrenia were associated with lethality in the younger suicide attempters. However, no factors were associated with SSA in the older adult group. Different mechanisms may underly the lethality in old age suicide.
From Learning Psychiatry to Becoming Psychiatrists: A Qualitative Study of Co-constructive Patient Simulation
Authors: Martin Andrés , Weller Indigo , Amsalem Doron , Adigun Ayodola , Jaarsma Debbie , Duvivier Robbert , de Carvalho-Filho Marco Antonio
Published: January 2021

Objectives: Co-constructive patient simulation (CCPS) is a novel medical education approach that provides a participatory and emotionally supportive alternative to traditional supervision and training. CCPS can adapt iteratively and in real time to emergent vicissitudes and challenges faced by clinicians. We describe the first implementation of CCPS in psychiatry.

Methods: We co-developed clinical scripts together with child and adolescent psychiatry senior fellows and professional actors with experience performing as simulated patients (SPs). We conducted the simulation sessions with interviewers blind to the content of case scenarios enacted by the SPs. Each hour-long simulation was followed by an hour-long debriefing session with all participants. We recorded and transcribed case preparation, simulation interactions, and debriefing sessions, and analyzed anonymized transcripts through qualitative analysis within a constructivist framework, aided by NVivo software.

Results: Each of six CCPS sessions was attended by a median of 13 participants (range, 11–14). The first three sessions were conducted in person; the last three, which took place during the COVID-19 pandemic, via synchronized videoconferencing. Each of the sessions centered on clinically challenging and affectively charged situations informed by trainees' prior experiences. Through iterative thematic analysis we derived an alliterating “9R” model centered on three types of Reflection: (a) in action/“while doing” (Regulate, Relate, and Reason); (b) on action/“having done” (Realities, Restraints, and Relationships); and (c) for action/“will be doing” (with opportunities for Repair and Reaffirmation).

Conclusions: CCPS is an experiential approach that fosters autonomous, meaningful, and individually tailored learning opportunities. CCPS and the 9R model for reflective practice can be effectively applied to psychiatry and have the potential to contribute uniquely to the educational needs of its trainees and practitioners.
Text Mining and Quantitative Research of Medical Service Policy: Sichuan Province as an Example
Authors: Zhang Huiqin , Zhu Liping , Zeng Chen , Chen Xudong
Published: January 2021

Medical service policy plays a prominent role in the development of a “Healthy China.” This paper constructs a three-dimensional framework for text mining of medical service policy using the elements of policy instruments, policy strength, and types of medical service activity. Taking Sichuan Province as an example, 221 medical service policy documents, issued by the government and related departments, are selected as the research sample; the policy instruments, policy strength, and medical service activity types are analyzed using ROST and Nvivo 11.0 software. It is concluded that the government needs to optimize the structure of policy instruments, to appropriately reduce the use of environmental policy instruments in particular, while increasing the use of demand-based policy instruments. It is necessary to strengthen the interaction between the various sub-policy instruments, and to increase the use of financial services, fiscal taxes, overseas communications, and strategic measures. An increase in the implementation of government policy assists the acceleration of the policy landing, the further improvement of the supervision system, and the safeguard mechanism of the three medicine policy linkage, which can improve the sustainability of the medical service policy, and further resolve the difficulty and expense of seeing a doctor.
Association Between Diabetic Retinopathy and Periodontitis—A Systematic Review
Authors: Alvarenga María Olimpia Paz , Miranda Giza Hellen Nonato , Ferreira Railson Oliveira , Saito Miki Taketomi , Fagundes Nathália Carolina Fernandes , Maia Lucianne Cople , Lima Rafael Rodrigues
Published: January 2021

Background: Diabetic retinopathy is a common microvascular complication in diabetic patients and is considered the main cause of visual loss worldwide. Periodontitis is a chronic inflammatory condition, which compromises dental supporting tissues. The chronic bacterial challenge in periodontitis is a persistent source of inflammatory mediators that may be associated with insulin resistance, increasing the risk of complications of diabetes mellitus. This systematic review aimed to summarize the evidence in the association between diabetic retinopathy and periodontitis.

Methods: This review was registered under the number CRD 42019142267. A search strategy in five electronic databases and a gray literature source was performed based on the PECO acronym. After data extraction, the qualitative synthesis and risk of bias analyses were performed using the Newcastle–Ottawa scale. The level of evidence of all studies taken together was evaluated through the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

Results: Out of the 253 citations screened, five cross-sectional studies met the eligibility criteria and were included in the qualitative analysis, in which two were judged to be of good quality, one as fair quality, and two as poor quality. Among the included studies, a significant relationship between the severity of periodontitis (CAL > 5 mm) and the severity of diabetic retinopathy (p < 0.05) was reported by four studies. Also, an association between both diseases in non-obese adults was found after adjustments [OR 2.206 (1.114–4.366); p = 0.0232). However, the analysis of evidence by GRADE assessment was rated as low.

Conclusions: Although the results of individual studies suggest an association between diabetic retinopathy and periodontitis, the quality of the body of evidence was judged to be low by the GRADE approach. Further studies with larger sample sizes, adequate models of cofounders' adjustments, and prospective analysis of periodontitis and diabetes conditions ought to be conducted to clarify this association.
Personality, Coping Strategies, and Mental Health in High-Performance Athletes During Confinement Derived From the COVID-19 Pandemic
Authors: Leguizamo Federico , Olmedilla Aurelio , Núñez Antonio , Verdaguer F. Javier Ponseti , Gómez-Espejo Verónica , Ruiz-Barquín Roberto , Garcia-Mas Alexandre
Published: January 2021

The COVID-19 outbreak has affected the sports field unprecedentedly. The emergency alert has deprived athletes of training in a suitable environment, as they are faced with cancellations of relevant events in their sports careers. This situation can cause stress levels and other emotional disorders similar to those experienced by athletes during periods of injury. Since the relationship between psychological factors and sports injuries is well-studied, the Global Psychological Model of Sports Injury (MGPLD) is applied to this historical situation for athletes. The purpose of this study was to analyze the relationships between perfectionism and trait anxiety with indicators of mental health (mood, depression, state anxiety, and stress) in high-performance athletes during confinement due to the COVID-19 pandemic, as well as to explore the coping strategies that athletes have applied and whether they are perceived as useful for managing negative emotional states. A cross-sectional study was conducted through online questionnaires during April 2020, adapting the Psychological Assessment Protocol of the High-Performance Sports Center of Murcia (Spain), to assess the psychological effects of confinement in a cross-cultural sample of 310 athletes (141 women and 169 men) from different countries in Europe, Asia, and America, and from diverse sports disciplines. The protocol comprised six instruments that test perfectionism, trait anxiety, mood states, stress, depression, coping strategies, and sleep. It was answered online via Google Forms. The results show that maladaptive perfectionism was related to all the indicators of athletes' mental health. However, athletes' levels of anxiety, stress, and depressive symptoms are relatively low, and the use of coping strategies such as cognitive restructuring and emotional calm was associated with lower levels of negative emotional states. Besides, the Iceberg Profile, a suitable fit for the mental health model, is observed in the mood of athletes, both in men and in women, although women showed higher levels of anxiety, stress, and depression than men. A strong relationship was observed between maladaptive perfectionism and martial arts sports discipline, superior to other sports. In short, it can be concluded that high-performance athletes in the studied sample showed negative emotional state values below the expected average. Finally, the proposals for practical applications of the results collected are discussed.
The Many Faces of Covid-19 at a Glance: A University Hospital Multidisciplinary Account From Milan, Italy
Authors: Priori Alberto , Baisi Alessandro , Banderali Giuseppe , Biglioli Federico , Bulfamante Gaetano , Canevini Maria Paola , Cariati Maurizio , Carugo Stefano , Cattaneo Marco , Cerri Amilcare , Chiumello Davide , Colosio Claudio , Cozzolino Mario , D'Arminio Monforte Antonella , Felisati Giovanni , Ferrari Daris , Gambini Orsola , Gardinali Marco , Marconi Anna Maria , Olivari Isotta , Orfeo Nicola Vincenzo , Opocher Enrico , Pietrogrande Luca , Previtera Antonino , Rossetti Luca , Vegni Elena , Toschi Vincenzo , Zuin Massimo , Centanni Stefano
Published: January 2021

In March 2020, northern Italy became the second country worldwide most affected by Covid-19 and the death toll overtook that in China. Hospital staff soon realized that Covid-19 was far more severe than expected from the few data available at that time. The Covid-19 pandemic forced hospitals to adjust to rapidly changing circumstances. We report our experience in a general teaching hospital in Milan, the capital of Lombardy, the most affected area in Italy. First, we briefly describe Lombardy's regional Covid-19-related health organizational changes as well as general hospital reorganization. We also provide a multidisciplinary report of the main clinical, radiological and pathological Covid-19 findings we observed in our patients.
Exponential Damping: The Key to Successful Containment of COVID-19
Authors: Zhang Feng , Zhang Jinmei , Cao Menglan , Zhang Yong , Hui Cang
Published: January 2021

Due to its excessive capacity for human-to-human transmission, the 2019 coronavirus disease (COVID-19) has now been declared a global public health emergency. Here we propose a simple model based on exponential infectious growth, but with a time-varying, largely damping, transmission rate. This model provides an excellent fit to the existing data for 46 countries with 10,000+ cases by 16 May 2020, five continents and the entire world. Hence, the model has largely captured the transmission patterns of the COVID-19 outbreak under a variety of intervention and control measures. The damping rate ranged from −0.0228 to 0.1669 d−1 globally (a negative damping rate represents acceleration in spread) and can greatly affect the duration of the outbreak and the eventual number of infections. Our model suggests that it is possible to defeat the COVID-19 pandemic by the end of 2020 through achieving a high damping rate (0.0615 d−1). However, the global damping rate is rather low (0.0504 d−1 before 26 April) and has dropped even further since late April (0.0168 d−1). Easing currently implemented control measures in countries with weak or no damping in transmission could lead to an exponential rebound of COVID-19 spread.
Depiction of Vaginal Microbiota in Women With High-Risk Human Papillomavirus Infection
Authors: Wei Zhen-Tong , Chen Hong-Liang , Wang Chun-Feng , Yang Gui-Lian , Han Shu-Mei , Zhang Song-Ling
Published: January 2021

Persistent infection with the carcinogenic human papillomavirus (HPV) is a prerequisite for the progression of cervical lesions and cancer. A growing body of research has focused on the functional role of the vaginal microbiota in the persistence of HPV infection. Understanding the microbial composition and structure in women with high-risk (hr)-HPV infection may help reveal associations between the vaginal microbiota and HPV infection, and identify potential biomarkers. Our study investigated the vaginal microbial community in women with and without hr-HPV infection, by using 16s rRNA gene sequencing. We found that microbial perturbations occurred in the early phase of hr-HPV infection. Lactobacillus and Sporolactobacillus were decreased, while bacteria related to bacterial vaginosis (BV), such as Gardnerella, Prevotella, Dialister, Slackia, Actinomyces, Porphyromonas, Peptoniphilus, Anaerococcus, Peptostreptococcus, Streptococcus, Ureaplasma, Megasphaera, and Mycoplasma were increased. Our results could offer insights into the correlations between hr-HPV and the vaginal microbiota in the early infection period, and provide indications that the predominance of some BV-associated bacteria during hr-HPV infection may increase the risk for cervical neoplasia.
Decreased CO2 Levels as Indicators of Possible Mechanical Ventilation-Induced Hyperventilation in COVID-19 Patients: A Retrospective Analysis
Authors: Hu Di , Li Jinpeng , Gao Rongfen , Wang Shipei , Li Qianqian , Chen Sichao , Huang Jianglong , Huang Yihui , Li Man , Long Wei , Liu Zeming , Guo Liang , Wu Xiaohui
Published: January 2021

Background: Six months since the outbreak of coronavirus disease (COVID-19), the pandemic continues to grow worldwide, although the outbreak in Wuhan, the worst-hit area, has been controlled. Thus, based on the clinical experience in Wuhan, we hypothesized that there is a relationship between the patient's CO2 levels and prognosis.

Methods: COVID-19 patients' information was retrospectively collected from medical records at the Leishenshan Hospital, Wuhan. Logistic and Cox regression analyses were conducted to determine the correlation between decreased CO2 levels and disease severity or mortality risk. The Kaplan-Meier curve analysis was coupled with the log-rank test to understand COVID-19 progression in patients with decreased CO2 levels. Curve fitting was used to confirm the correlation between computed tomography scores and CO2 levels.

Results: Cox regression analysis showed that the mortality risk of COVID-19 patients correlated with decreased CO2 levels. The adjusted hazard ratios for decreased CO2 levels in COVID-19 patients were 8.710 [95% confidence interval (CI): 2.773–27.365, P < 0.001], and 4.754 (95% CI: 1.380–16.370, P = 0.013). The adjusted odds ratio was 0.950 (95% CI: 0.431–2.094, P = 0.900). The Kaplan-Meier survival curves demonstrated that patients with decreased CO2 levels had a higher risk of mortality.

Conclusions: Decreased CO2 levels increased the mortality risk of COVID-19 patients, which might be caused by hyperventilation during mechanical ventilation. This finding provides important insights for clinical treatment recommendations.
Citizen Science for Bio-indication: Development of a Community-Based Index of Ecosystem Integrity for Assessing the Status of Afrotropical Riverine Ecosystems
Authors: Aura Christopher Mulanda , Nyamweya Chrisphine S. , Owiti Horace , Odoli Cyprian , Musa Safina , Njiru James M. , Nyakeya Kobingi , Masese Frank O.
Published: January 2021

The use of socioeconomic and cultural parameters in the assessment and biomonitoring of ecological health of aquatic ecosystems is still in its nascent stages. Yet, degradation of aquatic ecosystems has elicited concerns because of its bearing on social and economic development of communities consisting of marginalized and vulnerable groups, as well as the expenses and technical knowhow involved in biomonitoring approaches. In this study we developed a Citizen-based Index of Ecological Integrity (CIEI) for assessing and monitoring the ecological status of vulnerable African riverine ecosystems in Lake Victoria Basin, Kenya. The hypothesis is that the citizen-led socioeconomic and cultural metrics provides a more cost-effective broad view of ecosystems than other biomonitoring methods in the assessment of water resources in the developing countries. Selected rivers in the southern part of Lake Victoria (Rivers Kuja and Sondu-Mirui) recorded the highest CIEI than their northern counterparts (Rivers Yala and Nzoia) that had moderate to poor ecosystem integrities. The study demonstrates the usefulness of this approach to elucidate the source of impairment, the extent of impacts and provide a justifiable rationale to advice policy makers on developing guidelines for conservation and management of aquatic ecosystems. We recommend for adoption and promotion of the CIEI perspective in areas where such approaches appear defensible for the assessment of catchment-wide practices in areas with robust indigenous knowledge to provide a broad-view of the ecological health of the aquatic ecosystem.
A Review of Studies of Geomagnetic Storms and Auroral/Magnetospheric Substorms Based on the Electric Current Approach
Authors: Akasofu Syun-Ichi
Published: January 2021

The progress of space physics is reviewed from my personal point of view, particularly how I have reached my present understanding of auroral substorms and geomagnetic storms from the time of the earliest days of space physics. This review is somewhat unique in two ways. First of all, instead of taking the magnetic field line approach (including magnetic reconnection), I have taken the electric current approach; it consists of power supply (dynamo), transmission (currents/circuits), and dissipation (auroral/magnetospheric substorms). This is the basic way to study electromagnetic phenomena and it is much more instructive in understanding the physics involved in the chain processes. Secondly, this is not a textbook-like review, but it is hoped that my humble experience may be useful to see how a new science of space physics has evolved with a number of controversies. On the other hand, it can be seen that the electric current approach is still in a very rudiment stage. Thus, new generations of researchers are most welcome in taking this new way of studying auroral/magnetospheric substorms and geomagnetic storms.
Smart Technologies Lead to Smart Answers? On the Claim of Smart Sensing Technologies to Tackle Animal Related Societal Concerns in Europe Over Current Pig Husbandry Systems
Authors: Giersberg Mona F. , Meijboom Franck L. B.
Published: January 2021

Current pig production systems in Europe are subject to public criticism. At the same time, Precision Livestock Farming (PLF) technologies, which allow for automated animal monitoring are entering commercial pig farms. With their claim of improving animal health and welfare, these innovations may respond to public concerns. However, they may raise problems of societal acceptance themselves. In this review, we investigate whether the available literature allows for an analysis to which extent PLF can mitigate or reinforce societal concerns related to pig production. We first analyze papers on pig husbandry systems in general, and then those on PLF as an innovation in animal production. In general, there is a tension between citizens and farmers. Citizens hold rather negative attitudes whereas farmers evaluate pig production more positively. Literature on attitudes of other actors, such as veterinarians, is missing. Information on the attitudes toward PLF of stakeholders other than farmers is lacking. Possible challenges of societal acceptance of PLF and chances to overcome these are only discussed in theoretical approaches. We conclude that to analyze the role of PLF in addressing societal concerns over pig production, there is a need for further empirical research including attention to underlying values of all stakeholders. This should focus on the attitudes of the currently missing stakeholders toward pig husbandry in general, and on those of the wider society toward PLF. Only by means of additional data, it will be possible to evaluate whether PLF has the potential to address societal concerns related to pig production.
Climate Impact Mitigation Potential of Formation Flight
Authors: Marks Tobias , Dahlmann Katrin , Grewe Volker , Gollnick Volker , Linke Florian , Matthes Sigrun , Stumpf Eike , Swaid Majed , Unterstrasser Simon , Yamashita Hiroshi , Zumegen Clemens
Published: January 2021

The aerodynamic formation flight, which is also known as aircraft wake-surfing for efficiency (AWSE), enables aircraft to harvest the energy inherent in another aircraft’s wake vortex. As the thrust of the trailing aircraft can be reduced during cruise flight, the resulting benefit can be traded for longer flight time, larger range, less fuel consumption, or cost savings accordingly. Furthermore, as the amount and location of the emissions caused by the formation are subject to change and saturation effects in the cumulated wake of the formation can occur, AWSE can favorably affect the climate impact of the corresponding flights. In order to quantify these effects, we present an interdisciplinary approach combining the fields of aerodynamics, aircraft operations and atmospheric physics. The approach comprises an integrated model chain to assess the climate impact for a given air traffic scenario based on flight plan data, aerodynamic interactions between the formation members, detailed trajectory calculations as well as on an adapted climate model accounting for the saturation effects resulting from the proximity of the emissions of the formation members. Based on this approach, we derived representative AWSE scenarios for the world’s major airports by analyzing and assessing flight plans. The resulting formations were recalculated by a trajectory calculation tool and emission inventories for the scenarios were created. Based on these inventories, we quantitatively estimated the climate impact using the average temperature response (ATR) as climate metric, calculated as an average global near surface temperature change over a time horizon of 50 years. It is shown, that AWSE as a new operational procedure has a significant mitigation potential on climate impact. For a global formation flight scenario, we estimated the average relative change of climate response to range between 22% and 24% while the relative fuel saving effects sum up to 5–6%.
Operationalization of Interorganizational Fairness in Food Systems: From a Social Construct to Quantitative Indicators
Authors: Gudbrandsdottir Ingunn Y. , Olafsdottir Gudrun , Oddsson Gudmundur Valur , Stefansson Hlynur , Bogason Sigurdur G.
Published: January 2021

Fairness issues within food systems are of increasing concern for policy makers and other stakeholders. Given the topicality and policy relevance of fairness within food systems, there is value in exploring the subject further. Simulation modelling has been successfully used to develop and test policy interventions. However, the subjectivity and intangibleness of fairness perceptions make them difficult to operationalize in a quantitative model. The objective of this study is to facilitate research on fairness in food systems using simulation modelling by defining the social construct of fairness in model operational terms. The operationalization is conducted in two steps. First, the construct of fairness is conceptually defined in terms of its dimensions, antecedents, and consequences using the literature on interorganizational fairness. Then, by focusing specifically on fairness issues within food systems, the conceptual definition is used as a basis for the identification of proxy indicators of fairness. Seven groups of factors related to fairness perceptions were identified during the conceptualization phase: financial outcomes, operational outcomes, power, environmental stability, information sharing, relationship quality, and controls. From these factor groups, five indicators of fairness that are operational in a quantitative model were identified: profit margin as an indicator of distributive fairness and four indicators of procedural fairness related to market power and bargaining power.
Control of Meloidogyne graminicola a Root-Knot Nematode Using Rice Plants as Trap Crops: Preliminary Results
Authors: Sacchi Stefano , Torrini Giulia , Marianelli Leonardo , Mazza Giuseppe , Fumagalli Annachiara , Cavagna Beniamino , Ciampitti Mariangela , Roversi Pio Federico
Published: January 2021

Meloidogyne graminicola is one of the most harmful organisms in rice cultivation throughout the world. This pest was detected for the first time in mainland Europe (Northern Italy) in 2016 and was subsequently added to the EPPO Alert List. To date, few methods are available for the control of M. graminicola and new solutions are required. In 2019, field trials using rice plants as trap crops were performed in a Lombardy region rice field where five plots for three different management approaches were staked out: (i) Uncultivated; (ii) Treated: three separate cycles of rice production where plants were sown and destroyed each time at the second leaf stage; (iii) Control: rice was sown and left to grow until the end of the three cycles in treated plots. The results showed that in the treated plots, the nematode density and the root gall index were lower than for the other two management approaches. Moreover, the plant population density and rice plant growth were higher than the uncultivated and control plots. In conclusion, the use of the trap crop technique for the control of M. graminicola gave good results and thus it could be a new phytosanitary measure to control this pest in rice crop areas.
The Role of Technology in Greenhouse Agriculture: Towards a Sustainable Intensification in Campo de Dalías (Almería, Spain)
Authors: Mendoza-Fernández Antonio J. , Peña-Fernández Araceli , Molina Luis , Aguilera Pedro A.
Published: January 2021

Campo de Dalías, located in southeastern Spain, is the greatest European exponent of greenhouse agriculture. The development of this type of agriculture has led to an exponential economic development of one of the poorest areas of Spain, in a short period of time. Simultaneously, it has brought about a serious alteration of natural resources. This article will study the temporal evolution of changes in land use, and the exploitation of groundwater. Likewise, this study will delve into the technological development in greenhouses (irrigation techniques, new water resources, greenhouse structures or improvement in cultivation techniques) seeking a sustainable intensification of agriculture under plastic. This sustainable intensification also implies the conservation of existing natural areas.
A Possible Role of Copernicus Sentinel-2 Data to Support Common Agricultural Policy Controls in Agriculture
Authors: Sarvia Filippo , Xausa Elena , De Petris Samuele , Cantamessa Gianluca , Borgogno-Mondino Enrico
Published: January 2021

Farmers that intend to access Common Agricultural Policy (CAP) contributions must submit an application to the territorially competent Paying Agencies (PA). Agencies are called to verify consistency of CAP contributions requirements through ground campaigns. Recently, EU regulation (N. 746/2018) proposed an alternative methodology to control CAP applications based on Earth Observation data. Accordingly, this work was aimed at designing and implementing a prototype of service based on Copernicus Sentinel-2 (S2) data for the classification of soybean, corn, wheat, rice, and meadow crops. The approach relies on the classification of S2 NDVI time-series (TS) by “user-friendly” supervised classification algorithms: Minimum Distance (MD) and Random Forest (RF). The study area was located in the Vercelli province (NW Italy), which represents a strategic agricultural area in the Piemonte region. Crop classes separability proved to be a key factor during the classification process. Confusion matrices were generated with respect to ground checks (GCs); they showed a high Overall Accuracy (>80%) for both MD and RF approaches. With respect to MD and RF, a new raster layer was generated (hereinafter called Controls Map layer), mapping four levels of classification occurrences, useful for administrative procedures required by PA. The Control Map layer highlighted that only the eight percent of CAP 2019 applications appeared to be critical in terms of consistency between farmers’ declarations and classification results. Only for these ones, a GC was warmly suggested, while the 12% must be desirable and the 80% was not required. This information alone suggested that the proposed methodology is able to optimize GCs, making possible to focus ground checks on a limited number of fields, thus determining an economic saving for PA and/or a more effective strategy of controls.