bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Conceptual Representations on Attentional Bias
Authors: Lam Nietzsche
Published: May 2021

Many cultures have long been instilled with positive and negative concepts, which are associated with spatial metaphors, for instance,“I am feeling down” implies that I feel upset.  Recent research (Chasteen, Burdzy & Pratt, 2009; Meier & Robinson, 2005) has suggested that some concepts are strongly ingrained such that they influence how we attend to the environment.  In particular, certain positive concepts such as ‘almighty’ and ‘happiness’ bias attention upward and to the right, respectively and negative words‘lucifer’ and ‘mournful’ to the downward and to the left, respectively. Using a larger variety of positive and negative concepts than in previous studies, the current study seeks to determine whether concepts derived from pictures as well as words will produce a shift in attention. We present participants with words or pictures depicting either positive (e.g., smiling baby) or negative concepts (e.g., drug addict). We expect that a target displayed at the top or right‐side of the screen will be detected more quickly for positive concepts and targets displayed at the bottom or left‐side of the screen will be faster for negative.  However, whether the response times to targets in the valid conditions will be quicker for words than pictures is unknown.  Words could be faster than pictures because previous research has demonstrated that pictures can access concepts in our minds directly, whereas words access indirectly. On the other hand, another theory suggests that both words and pictures access concepts directly; therefore, there may be no difference between pictures and words.
VALIDASI BATAS ATAS BATAS BAWAH ESTIMASI DURASI GEDUNG KONSTRUKSI BERTINGKAT BERBASIS EARNED SCHEDULE
Authors: Widjaja Catherine Michellie , Anondho Basuki
Published: May 2021

Determination of estimated project completion is an activity that influenced the planning project since it can decide the success or failure of the project. However, duration is often not in accordance with prediction caused by uncertainty of the project. Calculation by probabilistic method is rated better than deterministic since probabilistic includes the uncertainty factor in its calculation. In addition, probabilistic method provides results in the form of intervals in upper to lower limit. In predicting project's final duration, the time-based Earned Schedule (ES) method is rated capable of overcoming the lack of cost-based Earned Value (EV). This research aims to determine the ongoing project’s upper and lower limit prediction duration using ES method through validation towards the completed project’s real duration. The average prediction of ongoing project duration will be calculated using ES by Microsoft Excel. The results will be validated towards the average real project duration using hypothesis tests of two independent population means. Result of average of upper limits indicates a valid value while the average of lower limits indicates a non-valid value with the upper limit value is 0.0025 week/m2 and lower limit is 0.0020 week/m2.Keywords: duration estimation; probabilistic; Earned Schedule; validation; upper limit and lower limit. AbstrakPenentuan estimasi penyelesaian proyek merupakan kegiatan yang berpengaruh dalam proses perencanaan karena dapat menentukan keberhasilan atau kegagalan proyek tersebut. Namun, durasi seringkali tidak sesuai dengan prediksi karena sifat ketidakpastian proyek. Perhitungan dengan metode probabilistik dinilai lebih baik daripada deterministik karena metode ini menyertakan unsur ketidakpastian dalam perhitungannya. Disamping itu, perhitungan probabilistik menyajikan hasil dalam bentuk interval yang dinyatakan dalam batas atas dan batas bawah. Dalam memprediksi durasi akhir proyek, metode Earned Schedule (ES) yang berbasis waktu dinilai mampu mengatasi kekurangan Earned Value (EV) yang berbasis biaya. Penelitian ini bertujuan untuk menetapkan nilai prediksi batas atas dan batas bawah proyek yang sedang berjalan dengan metode ES melalui validasi terhadap durasi nyata proyek yang sudah selesai. Rata-rata prediksi durasi proyek konstruksi yang sedang berjalan dihitung menggunakan metode ES dengan bantuan Microsoft Excel. Hasilnya kemudian divalidasi terhadap rata-rata durasi nyata proyek yang sudah selesai menggunakan uji hipotesis rata-rata sampel ganda. Hasil nilai batas atas proyek yang sedang berjalan dinyatakan valid dan nilai batas bawah dinyatakan tidak valid dengan nilai batas atas sebesar 0,0025 minggu/m2 dan batas bawah 0,0020 minggu/m2.
Atuação multiprofissional à mulher vítima de violência doméstica: assistência da Saúde da Família
Authors: Lima Caroline Silva de Araujo , Paiva Ana Caroline Grilo de , Aleixo Isadora Santos , Bandeira Lucas Alves , Gurgel Manoella Gotardo Aguiar , Nogueira Maria Eduarda Fraga , Jreige Poliana de Faria Miziara , Neto Sebastião Barreto Falcão , Holanda Vilma Raquel Lima Ramalho de , Corrêa Mônica Isaura
Published: May 2021

Objetivo: Identificar o papel da equipe de saúde da família no acolhimento às vítimas de violência doméstica e descrever os empecilhos presentes no serviço disponível. Revisão bibliográfica: É de suma importância que os profissionais da saúde tenham uma escuta qualificada e atenciosa, ofertando às vítimas uma garantia de confidencialidade possibilitando o relato da violência vivida. Além disso, reforça-se a importância do cuidado multidisciplinar, de forma a atender as demandas da vítima de maneira íntegra. Porém, a falta de articulação entre os serviços e entre os profissionais, a inadequação de estrutura física e a dificuldade de busca de uma rede de apoio são dificuldades encontradas pelas vítimas de violência doméstica, assim como, a falta de um protocolo e a revitimização. O despreparo acerca da temática devido a lacunas na formação do profissional de saúde e processos de qualificação incipiente, acarretam consequências negativas, como abordagem inadequada e práticas preconceituosas, fragilizando ainda mais a mulher. Considerações finais: Faz-se necessário que as UBS promovam ações de saúde, a capacitação dos profissionais da APS e a prevenção, ofertando serviços que auxiliem e acolham mulheres em situações de violência.
Hemoglobinopathy in pediatric population: A cross sectional study at tertiary care center in Assam
Authors: Mondal Uttam Kumar , Dowerah Pritikar , Mukherjee Ranajit
Published: May 2021

Objectives:

The objectives of the study were to find out the prevalence, epidemiology, and clinicohematological profile of hemoglobinopathies.

Material and Methods:

During the period of September 2010–August 2011, an observational study was done in the Department of Pediatrics, Assam Medical College and Hospital, Dibrugarh. Children (<12 years) suffering from chronic anemia were the study population.

Results:

Hemoglobinopathies were noted in 72 (35.0%) out of 206 chronic anemia cases, of which sickle cell disease (SCD) was found in 23 cases (11.2%), beta-thalassemia major (BTM) in 21 cases (10.2%), hemoglobin E (HbE)-β thalassemia in 12 cases (5.8%), HbE disease was seen in 10 cases (4.8%), and HbE trait and sickle cell trait (SCT) in 3 cases each. Overall hemoglobinopathy was most commonly seen among teagarden community in Assam. Clinical presentation ranged from completely asymptomatic to congestive heart failure. In majority cases, decreased mean Hb (%) and mean corpuscular volume were found. Anisopoikilocytosis, reticulocytosis, and target cells were frequently noted in peripheral blood smear.

Conclusion:

Chronic anemia cases should be screened for hemoglobinopathies as these genetic disorders are commonly seen in Assam. SCD and BTM are the major types of hemoglobinopathies. Heterozygous hemoglobinopathies (HbE trait and SCT) had lesser clinical manifestations. As the definitive treatment of hemoglobinopathies is still difficult to avail in this region, genetic counseling should be considered for hemoglobinopathy patients and their families as well, to prevent new cases.
Post-donation telephonic interview: A tool for active follow-up of voluntary whole blood donors for analysis of frequency and predisposing factors of adverse reactions
Authors: Navkudkar Anisha , Desai Priti , Rajadhakshaya Sunil
Published: May 2021

Objectives:

Blood donation experience by most donors is satisfactory; however, a few may encounter adverse reactions. Healthy, altruistic, voluntary blood donors ensure adequate blood supply despite the potential risk of adverse reactions. Post-donation follow-up is crucial to get information about these adverse reactions. This study aimed to evaluate the frequency and type of adverse donor reactions and their correlation with contributory factors if any among the blood donors in a tertiary care oncology center.

Material and Methods:

It was a prospective observational study of 1000 consecutive voluntary whole blood donors who consented to participate in the study. Donors were followed up telephonically on two instances (first after 24 h of donation and second after 2 weeks of donation) and were asked a self-structured donor questionnaire to collect information regarding the adverse donor reactions if any. An appropriate statistical tool was used for analysis (IBM, SPSS software).

Results:

Of the 1000 voluntary whole blood donors, 92.6% (926/1000) responded to telephonic calls on both occasions. Of these 926, 8.5% (79/926) donors experienced adverse reactions. All these donors experienced immediate reactions, that is, within 24 h of donation while none reported fresh adverse reactions beyond 24 h–2 weeks. Of the 79 donors, 60% (49/79) experienced vasovagal reactions (VVR) and 40% (32/79) experienced hematoma including two donors who experienced both. A total of 86% (68/79) of reactions occurred in outdoor blood donation camps while 14% (11/79) occurred in-house (indoor). First time donors, female donors, and donors with weight on the lower side were more prone to immediate VVR (P< 0.05). Of the 49 VVR, 76% (37/49) were mild, 18% (9/49) were moderate, and 6% (3/49) were severe. Most of the hematomas, that is, 90% (29/32) occurred at outdoor blood donation camps while 10% (3/32) occurred indoor. Most hematomas (53%) took more than 7 days to recover.

Conclusion:

Post-donation interview proves to be an efficient tool to acquire information about adverse donor reactions. This will help in improving donor safety and satisfaction and will have a positive impact on the national blood supply by improving the donor return rate. Blood transfusion services (BTSs) staff must be trained to promptly identify the donor reactions onsite and manage them to enhance the donation experience of voluntary donors. Post-donation follow-up will aid in getting the donation experience and BTS can develop strategies to enhance it. This will also help in donor hemovigilance in the future for the betterment of donor safety.
Are Indian obese children and adolescents at increased risk for Vitamin D deficiency?
Authors: Dabas Aashima , Aravind T. , Yadav Sangeeta , Mantan Mukta , Kaushik Smita
Published: May 2021

Objectives:

Obesity has been mentioned as a high risk factor for Vitamin D deficiency (VDD) requiring supplementation in Indian children.

Material and Methods:

Forty obese and age-matched non-obese subjects (age 5–18 years) were assessed for lifestyle parameters, metabolic profile, and serum 25-hydroxyvitamin D (25OHD). VDD was defined as serum 25OHD < 12 ng/mL.

Results:

Mean 25OHD was comparable among obese and controls (15.0 ± 9.95 and 15.1 ± 4.79 ng/mL; P = 0.97) with VDD seen in 82% of cases and 85% of controls. Pubertal cases had lower 25OHD values than prepubertal obese cases (10.78 ± 4.69 and 17.2 ± 11 ng/mL; P = 0.06). Mean duration of physical activity (<2 h/week) and screen time (>2 h/day) was similar across prepubertal and pubertal groups and between obese and controls. Obesity was not associated with risk for VDD among cases and controls (odds ratio 0.83, 95% C.I. 0.25–2.7, P = 0.76).

Conclusion:

Obese pubertal subjects were more at risk for VDD than prepubertal subjects. Routine Vitamin D supplementation to obese Indian children may be considered during adolescence.
Hydroxychloroquine as prophylaxis when treating patients with coronavirus disease 2019 – Perception of frontline health care workers in South India
Authors: Mani Karthik , Velan Minu
Published: May 2021

Objectives:

In March 2020, the Indian Council of Medical Research (ICMR) recommended the use of hydroxychloroquine (HCQ) for prophylaxis in asymptomatic health care workers who care for suspected or confirmed patients and household contacts of confirmed patients with coronavirus disease 2019 (COVID-19). This recommendation was received by health-care practitioners with mixed opinions. The objectives of the study were to explore the views of frontline health-care practitioners (physicians, nurses, and physician assistants) in South India related to the ICMR recommendation of HCQ prophylaxis.

Material and Methods:

The survey research design was used to conduct this study. A ten-item electronic survey was developed based on the research question. The survey link was shared with frontline health-care practitioners in South India through email and WhatsApp messages identified through convenience sampling. Furthermore, the recipients were requested to forward the link to other frontline health-care professionals in their network (snowball sampling). Data were collected from April 16, 2020, to May 7, 2020.

Results:

The number of responses received was 132. Of 80 respondents who treated or anticipate treating patients with COVID-19, only 29 respondents reported that they complied with the ICMR’s HCQ chemoprophylaxis recommendation. Participants expressed concerns about the side effects and lack of conclusive evidence.

Conclusion:

Frontline health care workers in South India have mixed opinions with regard to the safety of HCQ prophylaxis. To promote the acceptance of and successful implementation of prophylaxis recommendations, it is essential that health authorities consider research evidence and seek stakeholder input before finalizing recommendations.
Perceived stress among doctors working in a dedicated COVID-19 hospital in North India
Authors: Garg Rohit , Singla Aditi , Garg Jasmin
Published: May 2021

Objectives:

The present study was aimed to assess the level of perceived stress among doctors working in COVID-19 ward in a tertiary care medical college and hospital of North India and to find the association of stress with time spent in ward, age, and designation of the doctors.

Material and Methods:

It was a cross-sectional, Google-based survey conducted in October and November 2020. The form was circulated and recorded the sociodemographic data, time spent in the COVID-19 ward, etc. The perceived stress scale (PSS) was used to assess the level of stress. Appropriate statistical analysis was used and all ethical considerations were followed.

Results:

Mean PSS score of the sample was 22.22 ± 7.13. Twenty-five (10%) doctors reported low stress (mean PSS score 0–13). Moderate (mean PSS score 14-26) and high stress (mean PSS score >26) were found among 156 (62.4%) and 69 (27.6%) doctors, respectively. Perceived stress showed significant negative correlation with age and significant positive correlation with hours spent in COVID ward in a week. Senior residents and junior residents had significantly higher perceived stress than faculty (P - 0.001**). Nearly 50% of doctors (fairly often or very often) felt nervous and stressed, angered because they felt out of control, unable to control important things in their lives, and have been upset because of something that happened unexpectedly. About 40% felt (fairly often or very often) that they could not cope with all the things they had to do. Nearly one-third of doctors felt (fairly or very often) that difficulties were piling up so high that they could not overcome them.

Conclusion:

Doctors working in COVID-19 wards perceive considerable stress. Stress management should be an integral part of the curriculum of doctors so that they can serve the humanity efficiently and effectively during the pandemic and in future.
Do You Have a Room for Us in Your IT? An Economic Analysis of Shared IT Services and Implications for IT
Authors: Chen Min , Pang Min-Seok , Kumar Subodha
Published: May 2021

We are witnessing an interesting and unique phenomenon in enterprise information technology (IT) adoption and management in public-sector organizations: shared IT services. Instead of implementing separate IT services, governments come together to pool their IT resources into one single IT service. In this study, we develop a game-theoretic model to analyze the governments’ decision to share IT services and understand how the introduction of shared services transforms the strategic interactions between the governments and the vendor. We study three common regimes used in the adoption of shared IT services: (1) a cost-sharing regime where costs are split proportionally, (2) a profit-center regime where one government charges a surplus-maximization price to the other, and (3) a coordination regime where governments coordinate their decisions to maximize aggregate surplus. Our analyses generate several intriguing findings. First, although charging a surplus-maximizing price seems to be a lucrative option, we find that a government does not always benefit by acting as a profit center. Second, the cost-sharing regime does not always incentivize the shared service adoption despite being often viewed as a fairer and more convenient arrangement. Third, we find that there can be significant under-utilization of shared services in the absence of proper coordination, in a sense that the governments may choose not to share their IT services even if doing so would increase their aggregate surplus. Finally, even though coordination promotes the adoption of shared IT services, it can sometimes be inefficient from the social welfare’s perspective because the increase in governments’ surplus can be outweighed by the decrease in the vendor’s profit. We also present a range of extensions to our model to show that our main takeaways carry over when some model assumptions are relaxed.
Space Syntax Guide to Optimize Shopping Mall
Authors: Andi Andi , Abednego Ivan Adiel , Gultom Bontor Jumaylinda Br.
Published: May 2021

The shopping mall is a facility for profit-making with a complex spatial configuration that prioritizes the effectiveness in any aspects. The spatial configuration of a shopping mall needs more than a rule of thumb or a subjective judgment to optimize it. Many researchers have conducted studies of shopping mall spatial configuration by the theory and method of space syntax. But, the complexity of space syntax turns it hard to understand or apply in practical use. Due to the complexity of both shopping mall and space syntax, a guide is needed for practical directions to optimize shopping mall. This article review combines and synthesizes the findings of space syntax precedent studies. The scope of the study is on the building configuration scale (mesoscale). As the result, the optimization of a shopping mall can be measure by space syntax through measurement of connectivity, depth, integration, choice, and intelligibility. Each measurement has a different purpose. The most used measurement in shopping mall study is integration. The spatial configuration of the mall can be represented by the axial map, convex map, isovist map, VGA map, and agent-based in space syntax analyses. The most suitable map for shopping mall analysis is the VGA map because it shows the visual quality is vital in shopping mall design. There are several aspects of the shopping mall that can be adjusted or modified to optimize the shopping mall. Those aspects are pedestrian flows, horizontal complexity, vertical complexity, tenant type allocation, visual quality, retail placement, and anchor placement.
Tale of Two “Rumah”
Authors: Chiang Bien
Published: May 2021

In this paper, I will juxtapose the socio-economic histories of two Austronesian communities in order to highlight the working of a key cultural concept, “house” or rumah, in both communities in the face of encroaching contemporary state and market forces. The communities under consideration are an Iban longhouse community of Sarawak and a Paiwan community of Southern Taiwan. Both group honored a kind of precedence in terms of land occupancy and the utilization of natural resources. Both group follow a rather fundamental cognatic principle in kinship recognition, household division and property transmission. While a comprehensive comparison of the two on so complex a subject is apparently way beyond the scope of a conference paper, I choose here to focus on the interplay of state policy (both colonial and independent) and market force on land tenure and land utilization among the two communities, and hope to demonstrate the upholding of the notion umah as a value in these peoples modernization strategies. Even though the contents, scopes and representations of the notion of “House” are different in these two societies, its centralities in their respective social and cultural systems are fascinatingly comparable. I do not intent to say that these two local communities of the Austronesian experience no difficulties whatsoever in their ever-increasing involvement in the national, regional and global systems.  From what we observe, however, we do see that they are not just surviving the encroaching external impacts, they continue to exist as two “rumah”.
DOES ALTITUDE AND FOREST DENSITY AFFECT ECONOMIC GROWTH? A CASE STUDY OF KALIMANTAN BARAT
Authors: Islahiyah Djihan , Vikki Vikki
Published: May 2021

Kalimantan Barat is one of the individual provinces in Kalimantan due to its diverse geographical elevation among all districts. Mountains and hills dominate the districts near the border; lowlands and river banks dominate the urban areas. A geographical indication is a barrier to economic growth, as a simple growth from limited transportation. Efforts to optimize the economic sector are also carried out in forest management, including Kalimantan Barat as one of the world's lungs. The conversion of forest land functions is suspected to increase economic growth even though it must balance nature. This study aims to determine the significance of altitude as a fixed geographical indicator and forest density as a natural condition that can vary according to human activities. The height of area data and forest density, and the average economic growth in 14 districts/cities in Kalimantan Barat uses the Panel Least Square method. As a result, area height has a negative and significant effect on economic growth, whereas forest density has no such relationship. Simultaneously, both variable is having a substantial impact on economic growth in Kalimantan Barat.
Physiological and Molecular Biology of High Temperature Stress in Plants
Authors:   National Maize Improvement Center, China Agricultural University, Beijing, PR China, J Ye , T Zhong ,   National Maize Improvement Center, China Agricultural University, Beijing, PR China, D Yu ,   National Maize Improvement Center, China Agricultural University, Beijing, PR China, S Sun ,   National Maize Improvement Center, China Agricultural University, Beijing, PR China
Published: May 2021

During the past few years, climate change induced by global warming had caused the appearance of extreme high temperatures worldwide, which had resulted in devastating damage to crop production. High Temperature Stress (HTS) is becoming an increasingly significant problem for agricultural production. Recent studies have elucidated the complex regulatory networks and versatile metabolites involved in HTS tolerance. Here, we provided an overview of current knowledge regarding the adverse effect of HTS on plant growth and development, the impairment of HTS on photosynthesis and membrane system, the role of carbohydrate metabolism, accumulation of osmo-protectants and secondary metabolites, the induced production of Reactive Oxygen Species (ROSs) and ROS detoxification system, and the synthesis of protective proteins like Heat Shock Proteins (HSPs) in HTS tolerance. Furthermore, the role of different phytohormones in plant response to HTS were discussed and epigenetic modifications are reported to be one of the three major signaling pathways associated with HTS response in plants, through the development of a ‘stress memory’ that is generated by hypomethylation to improve the plant’s survival under recurring HTS conditions. These physiological and molecular knowledge underlying plant response to cope with HTS will be helpful for the future directions of breeding crop tolerance to HTS using these factors or other strategies for agricultural applications.
Assessment of Quantitative Traits of Rajma Bean (Phaseoulus vulgaris L.) Accessions for Yield and Yield Attributing Traits in Multi-Environments of Nepal
Authors:   Coordinator/Senior Scientist and STO, Grain Legumes Research Program, Nepal, R Darai , R Sah ,   Coordinator/Senior Scientist and STO, Grain Legumes Research Program, Nepal, JB Sah ,   Directorate of Agricultural Research, Nepal, B Gupta ,   Jute Research Program, Itahari, Nepal, S Rasaili ,   Directorate of Agricultural Research, Nepal
Published: May 2021

Rajma (Phaseolus vulgaris L) known as the common bean, French bean, kidney bean, bush bean, and pole bean is the most important grain legume of Nepal which covers about 10,529 ha areas along with the productivity of 1477kgha-1. Generally it is grown during summer in mid/high hills and during winter (post rainy) season interai/inner terai in rice and maize based eco-system. Now Rajma bean is being popular as the cash crop in the province 3, 5 and 6 because of producing organic products and tastier quality. Multi-environment trials was carried out at Nepalgunj, Parwanipur, Itahari and Surkhet during the winter season of 2014-2017 comprised of 10 diverse Rajma genotypes in Randomized Complete Block Design with three replications in order to evaluate the quantitative variation with respect to yield and yield contributing traits. The combined analysis of variance showed that the highly significant differences among the genotypes and locations in the traits like days to flowering, days to maturity, plant height, hundred seed weight and grain yield. However; there was not any GxE interaction effect found in days to flowering, days to maturity and grain yield. Mean yield performances showed that the genotype PDR-14 (2341kgha-1) produced the highest yield followed by Utkarsh (2332kgha-1) and Arun-2 (2021kgha-1). In conclusion, PDR-14 gave 9-56% higher yield among the genotypes and its stability analysis test also indicated that PDR-14 was found a highly stable across the environments and over the years. Variegated red kidney shape seed, white flowers along with dwarf and glabrous leaf pubescence is the DUS trait of the PDR-14 and recommended for terai/inner terai to high hills.
Hemophagocytic Lymphohistiocytosis after Initiation of Combined Immunotherapy for Metastatic Melanoma
Authors:   Department of Dermatology, Ruhr-University Bochum, Germany, T Gambichler , NA Rached ,   Department of Dermatology, Ruhr-University Bochum, Germany, N Nowack ,   Department of Dermatology, Ruhr-University Bochum, Germany, B Behle ,   Department of Dermatology, Ruhr-University Bochum, Germany, L Susok ,   Department of Dermatology, Ruhr-University Bochum, Germany
Published: May 2021

Hemophagocytic Lymphohistiocytosis (HLH), which is a severe, potentially fatal condition characterized by T lymphocyte overactivation, is predominantly caused by infections, hematological malignancies, and autoimmune conditions. HLH due to therapy with Immune Checkpoint Inhibitors (ICI) has rarely been reported. We describe a 60-year-old male with metastatic melanoma who developed HLH after the initiation of nivolumab plus ipilimumab treatment. Prompt diagnosis and high-dose mono-prednisolone therapy resulted in rapid resolution of his subjective symptoms and laboratory findings. Apart from this case presentation we provide a brief overview on clinical characteristics of previously observed ICI-induced HLH cases. Given the increasing use of ICI in a variety of cancers, the frequency of HLH will very likely raise. HLH morbidity and mortality are often the result of delayed diagnosis and inappropriate treatment. Hence, HLH must be considered in ICI-treated cancer patients who present with symptoms such as fever, cytopenias and hyperferritinemia.
Acute Lipoprotein (a) Reduction after PCI and the Incidence of Restenosis: a Clinical Study
Authors:   Department of Cardiology, Pneumology and Angiology, University of Witten/Herdecke, Germany, Hermes M Schulte , Wiele O Klein ,   Department of Cardiology, University of Witten/ Herdecke, Germany, PC Schulte ,   Department of Internal Medicine III, University of Witten/Herdecke, Germany, M Seyfarth ,   Department of Cardiology, University of Witten/ Herdecke, Germany
Published: May 2021

Background: Lipoprotein (a) [Lp(a)] is a well-documented independent risk factor for Coronary Artery Disease (CAD) that also affects the lipid and coagulation systems. Nevertheless, the influence of Lp (a) on the manifestation of restenosis after Percutaneous Coronary Intervention (PCI) is not fully explored. We investigate Lp (a), fibrinogen, and plasminogen levels pre- and post-Percutaneous Coronary Intervention (PCI) to assess interaction of Lp (a) with the coagulation system. Methods: Patients with CAD and PCI with bare metal stents were recruited between August 1998 and June 1999. Blood samples to measure Lp (a), plasminogen, and fibrinogen were taken pre-PCI, immediately after PCI, and on days one and three after PCI. Patients were followed up after six months by scheduled Coronary Angiogram (CAG). Results: A total of 89 patients were recruited, 81 of which were examined by CAG, and 28 had restenosis after PCI (34.5%). Following PCI, patients with restenosis had a larger decrease in Lp (a) levels and fibrinogen neither of both had reached baseline by day three (Lp (a) p=0.008, fibrinogen p=0.0121). Conclusions: From the fact that neither Lp (a), nor fibrinogen, or plasminogen had returned to baseline levels by day three after PCI, we hypothesise that there may exist a bridge between Lp (a) and the thrombosis and fibrinolysis pathways at the site of vascular injury after PCI which promotes restenosis after PCI.
Fatal Mesenteric Ischemia in a Severely Ill COVID-19 Patient: a Case Report
Authors:   Medical and Infectious Diseases ICU (MI2), Bichat-Claude Bernard Hospital, France, PH Wicky , D Faille ,   University of Paris, Bichat-Claude Bernard Hospital, France, L De Chaisemartin ,   University of Paris-Saclay, INSERM UMR996, France, P Nicaise Roland ,   University of Paris, National Institute for Health and Medical Research (INSERM), France, V Granger ,   Bichat-Claude Bernard Hospital, Autoimmunity and Hypersensitivity Immunology Laboratory, France, I Zhoury ,   Bichat-Claude Bernard Hospital, Pathological Anatomy Laboratory, France, J Patrier ,   Medical and Infectious Diseases ICU (MI2), Bichat-Claude Bernard Hospital, France, N Pote ,   Bichat-Claude Bernard Hospital, Pathological Anatomy Laboratory, France, E De Montmollin ,   National Institute for Health and Medical Research (INSERM), IAME, France, R Sonneville ,   University of Paris, National Institute for Health and Medical Research (INSERM), France, N Ajzenberg ,   University of Paris, Bichat-Claude Bernard Hospital, France, JF Timsit ,   Medical and Infectious Diseases ICU (MI2), Bichat-Claude Bernard Hospital, France
Published: May 2021

Background: Emerging data suggest a complex role for immuno-thrombosis in the thrombotic complications in COVID-19. We report the case of a fatal mesenteric ischemia to illustrate the mechanisms of endothelial dysfunction in the gut, and the resulting hypercoagulability. Case Report: A 58-year-old woman was admitted in Intensive Care Unit, with initial severe acute respiratory distress syndrome due to SARS-CoV-2 pneumonia. Her respiratory status worsened, with a septic shock thirteen days after symptoms onset. The blood culture was positive with Pseudomonas aeruginosa and Candida. A rapid consecutive deterioration leading to multiorgan failure revealed colic perforation complicated with secondary peritonitis. Histopathological findings revealed small vein occlusions. Surprisingly, no SARS-CoV-2 viral particles could be detected in the bowel. We found intense endothelial dysfunction, contrasting with only mild neutrophil activation. A major increase in von Willebrand factor and resistance to fibrinolysis were the main hemostatic abnormalities. Discussion: This case highlights that COVID-19-associated hypercoagulability can lead to early primitive thrombotic events in small vessels, and adds new evidence concerning a potential role for immuno-thrombosis. Close monitoring of endothelial dysfunction, and further consideration of new targets to prevent thrombosis by adjunctive therapies may thus appear fundamental.
Is There Any Association between Blood Group and Impacted Third Molars?
Authors:   Shiraz University of Medical Sciences, Student Research Committee, Iran, H Ahmadi , A Ebrahimi ,   Shiraz University of Medical Sciences, Student Research Committee, Iran, F Ghorbani ,   Department of Oral and Maxillofacial Surgery, Shiraz University of Medical Sciences, Iran
Published: May 2021

Background: Blood type is an important genetic characteristic that is inherited from parents’ thorough alleles, and might be related to several problems, including, dental conditions. In the present study we examined the probable association of impacted teeth and blood groups. Methods: This retrospective study was done on patients who were referred for obtaining oral radiographs. For each blood group and Rh factor, we randomly selected 40 patients. The type of blood group of the participants was also obtained from the medical records available in the patients’ history archives. Results: A total of 320 participants contributed to the study, 136 (42%) were males and 184 (57%) were females. The mean age was 29 ± 6 years. Among all participants, 205 (64%) had no impacted third molar, 26 (8%) had one impacted third molar, 43 (13%) had 2 impacted third molars, 5 (1%) had 3 impacted third molars, and 41 (12%) had 4 impacted molars. Conclusion: In the present study no significant association was found between ABO blood groups and impacted third molars.
Aquatic Ecosystems and Climate Changes: Data Gaps in Relation to Flooding Events
Authors:   Environment and Health Department, Istituto Superiore di Sanità, Italy, S Marcheggiani , C Puccinelli ,   Environment and Health Department, Istituto Superiore di Sanità, Italy, L Mancini ,   Environment and Health Department, Istituto Superiore di Sanità, Italy, F Chiudioni ,   Environment and Health Department, Istituto Superiore di Sanità, Italy, I Lacchetti ,   Environment and Health Department, Istituto Superiore di Sanità, Italy, M Carere ,   Environment and Health Department, Istituto Superiore di Sanità, Italy, L Tancioni ,   Biology Department, University of Rome Tor Vergata, Italy
Published: May 2021

At European level the strategy on adaptation to climate changes promoted adaptation plans at all levels and has recommended the need to bridge the gaps through applications of actions at local level. In the paper has been remarked that there are some gaps in the European legislation that should be solved through the funding of more research projects and pilot studies; for example the use of microbiological monitoring, not foreseen by the water framework directive, can help to identify and prevent effect adverse on human health. In this study we propose an operative methodology to be applied at local level with the aim to support the institutional requirements for risk management before and after flooding events, based on a multi-criteria approach. This integrated monitoring plan could represent a shared methodology with the aim to give a contribution for the management of the risks of extreme weather events such as flooding for human health and ecosystem protection.
The Beneficial Effects of Emotional Intelligence Training for Critical Care Nurses in Cairo, Egypt: A QuasiExperimental Study
Authors:   Fatima College of Health Sciences, United Arab Emirates, HA Abdel-Fattah , GK Sallam ,   Department of Obstetrics and Gynecology, UAE University College of Medicine and Health Sciences, United Arab Emirates, AS Hendy ,   Department of Paediatrics, Ain Shams University, Egypt, A Abozeid ,   Ain Shams University, Medical Surgical Nursing, Egypt, N Rodenhurst ,   Aberystwyth University, Wales
Published: May 2021

Background: Many critical care nurses commencing work in this environment may lack resilience, and because of the stress of the critical care environment, coping mechanisms need to be developed. Research Aims: To discover whether emotional intelligence training for nurses at critical care units in Cairo, Egypt may alleviate the problem of job burnout. Methodology: A Quasi-experimental study was conducted at two critical care units: a Cardiac Surgery Academy and El Demerdash Hospital “Cardiac care unit and intensive care unit”, both of which are affiliated to Ain Shams University, Egypt, Cairo. The subjects were 200 critical care nurses. A selfadministered questionnaire containing three parts (demographic data of nurses, Wong and Law Emotional Intelligence Scale and Maslach burnout inventory). Results: There was marked improvement in all domains of emotional intelligence scores among the nurses after the training. There was marked improvement in all domains of the burnout scale scores of the nurses’ surveys post intervention. Marital status, experience, and emotional intelligence were all seen to be predictors of higher burnout rates. Conclusions: The present study revealed that emotional intelligence training had a positive impact on nurses’ experience of job burnout.
BrdU Positive Cells Induced in a Genetic Mouse Model of Glaucoma
Authors:   Department of Biological Sciences, Western Michigan University, Kalamazoo MI, 49008, United States, JR Paris , NC Sklar ,   Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, United States, CL Linn ,   Department of Biological Sciences, Western Michigan University, Kalamazoo MI, 49008, United States
Published: May 2021

Previous studies have shown that eye drop application of the selective a7 nicotinic acetylcholine receptor agonist, PNU-282987, induces neurogenesis of RGCs in adult wild-type rodents. This study was designed to test the hypothesis that PNU-282987 reverses the loss of RGCs associated with glaucoma. A DBA/2J mouse model that auto-induces a glaucoma-like condition in adulthood was used for these studies. Short-term effects using PNU-282987 and BrdU eye drop treatments were examined, as well as the effects of early treatment and the effects in a chronic early treatment group in DBA/2J mice aged 3, 6 and 10 months. With and without treatment, retinas were removed, fixed, immunostained and RGC counts were assessed. IOP measurements were obtained weekly using a Tonolab tonometer. Results showed an average typical loss of BrdU positive RGCs by 29% by 10 months of age in this DBA/2J colony corresponding with a significant increase in IOP. However, the two-week short term application of PNU-282987 and BrdU induced a significant 21% increase in RGCs for DBA/2J mice at all ages. Chronic early PNU-282987 treatment produced a similarly significant increase in RGCs, while acute early treatment had no effect on RGC numbers. IOP measurements were not affected with PNU-282987 treatment. These studies demonstrated that 2-week treatment with PNU-282987, as well as chronic long-term treatment, induced a significant increase in the number of RGCs in the DBA/2J retina, counteracting the effects of the DBA/2J genetic glaucoma-like condition. These results suggest a potential future treatment of degenerative retinal diseases with PNU-282987.
ВЗАИМОСВЯЗЬ МОРФОМЕТРИЧЕСКИХ ПАРАМЕТРОВ СЕЛЕЗЕНКИ И АНТРОПОМЕТРИЧЕСКИХ ПОКАЗАТЕЛЕЙ ЛИЦ ЖЕНСКОГО ПОЛА ПЕРВОГО ПЕРИОДА ЗРЕЛОГО ВОЗРАСТА В ДОНЕЦКОМ РЕГИОНЕ
Authors: Васильев В. А. , Басий Р. В. , Кулиш А. И. , Бешуля О. А.
Published: May 2021

Вступление. Селезенка является индикатором большого числа патологических состояний. Наиболее информативным для оценки размеров селезенки и ее структуры является метод ультразвукового исследования. Корректную оценку морфометрических параметров селезенки, полученных при ультразвуковом исследовании, необходимо осуществлять с учетом половозрастных, антропометрических и соматотипологических особенностей исследуемого. Цель работы. Определить морфометрический эталон нормы селезенки, установить взаимосвязь количественных параметров органа и антропометрических показателей практически здоровых лиц женского пола первого периода зрелого возраста в Донецком регионе.Материал и методы. Объект исследования: 60 условно здоровых женщин в возрасте от 21 до 35 лет.  На первом этапе работы проводилось ультразвуковое исследование селезенки. Определялись следующие морфометрические параметры: длина, ширина и толщина селезенки, а также рассчитывался объем селезенки. Далее проводилась антропометрия обследуемых с целью последующего определения соматотипа по методике Б.Х. Хит, Д.Л. Картера. Полученные результаты обрабатывались в пакете прикладных программ Statistica 10. Результаты и обсуждение. Результаты соматотипирования обследуемых позволяют утверждать, что среди лиц женского пола первого периода зрелого возраста Донецкого региона преобладают эндо-мезоморфный и мезо-эндоморфный соматотипы. Среднее значение показателя роста всех обследуемых – 165,5±0,7 см, массы тела – 59,7±1,0 кг; среднее значение длины селезенки, полученное при ультразвуковом исследовании, составило 10,9±0,1 см, ширины – 5,8±0,1 см.  Медиана показателя толщины органа оказалась равна 4,7±0,1 см, объема селезенки – 154,8±5,4 см3.На следующем этапе работы было определено наличие линейной корреляционной связи между величинами изучаемых показателей как независимо от соматотипа, так и у лиц наиболее часто встречающегося –  эндо-мезоморфного соматотипа. У всех исследуемых была установлена средняя по силе положительная линейная корреляционная связь между длиной и шириной селезенки. У лиц эндо-мезоморфного типа телосложения были установлены средние положительные линейные корреляционные связи между ростом и длиной селезенки, весом и длиной органа, а также между длиной селезенки и ее шириной.Выводы. Получены средние значения морфометрических параметров селезенки, которые могут быть использованы в качестве ультразвукового эталона нормы. Установлена взаимосвязь между количественными параметрами селезенки и антропометрическими показателями у лиц женского пола первого периода зрелого возраста в Донецком регионе.
Jalan Terjal Implementasi Reconciliation and Healing Foundation oleh Korea Selatan dalam Hubungan dengan Jepang
Authors: Primastuti Puspasari Maria Aurelia , Susiatiningsih Hermini
Published: May 2021

Comfort Women Agreement sebagai upaya penyelesaian isu comfort women diantara Korea Selatan dan Jepang telah tercapai di tahun 2015. Sebagai tindak lanjut dalam perwujudan skema perjanjian tersebut, salah satu kebijakan yang harus diimplementasikan oleh pemerintah Korea Selatan yakni mendirikan sebuah yayasan untuk memberi dukungan kepada semua mantan comfort women dalam penyembuhan luka psikologis melalui kontribusi dana dari anggaran Pemerintah Jepang. Namun Comfort Women Agreement dan pendirian yayasan yang kemudian dinamai Reconciliation and Healing Foundation masih ditanggapi dengan respon negatif dari masyarakat dan korban comfort women di Korea Selatan. Hal ini menjadi jalan terjal yang dihadapi dalam proses implementasi Reconciliation and Healing Foundation dan berujung pada pembubaran yayasan tersebut pada tahun 2018. Penelitian ini bermaksud menjelaskan bagaimana faktor-faktor yang mempengaruhi pelaksanaan implementasi yayasan tersebut oleh Korea Selatan dalam skema perwujudan Comfort Women Agreement. Untuk menganalisis fenomena tersebut akan menggunakan teori implementasi kebijakan dari Merilee S. Grindle. Hasil dari penelitian ini menjelaskan bagaimana konten kebijakan dan lingkungan implementasi menjadi faktor yang mengakibatkan terbentuknya jalan terjal dalam proses implementasi Reconciliation and Healing Foundation.
Fashion, Feminisme dan Hubungan Internasional : Perdebatan dalam Literatur
Authors: Soetjipto Ani , Chandra Ayu
Published: May 2021

Artikel ini akan membahas bagaimana fashion dikaji melalui kaca mata feminis dalam studi Hubungan Internasional. Artikel ini hadir dengan melihat fashion sebagai salah satu produk dari pop culture, telah berperan signifikan dalam mendorong upaya pencapaian kepentingan suatu aktor politik—terutama sebagai alat konstruksi identitas. Kajian ini juga mendorong perkembangan kajian mengenai pop culture dalam studi Hubungan Internasional. Bahasan dibuka dengan menyajikan perdebatan literatur mengenai fashion dan feminisme. kemudian dilanjut dengan bagaimana narasi perdebatan tersebut dijabarkan dalam konteks Hubungan Internasional. Selanjutnya, melihat masalah fashion, feminisme dan Hubungan Internasional dalam konteks Indonesia dari segi produksi dan konsumsi.  Artikel ini menawarkan perspektif baru dalam melihat fashion sebagai second-order representation dari politik internasional yang berdampak pada isu di ranah domestik.
A percepção de escolares sobre o Programa Saúde na Escola avaliada por desenhos e narrativas: um estudo de caso em Belo Horizonte
Authors: Oliveira Fernanda Piana Santos Lima de , Rota Júnior César , Vargas Andrea Maria Duarte , Hartz Zulmira , Dias Sónia , Ferreira Efigênia Ferreira e
Published: May 2021

O Programa Saúde na Escola é uma política intersetorial, resultado do trabalho entre o Ministério da Saúde e o Ministério da Educação, cuja finalidade é ampliar as ações de saúde aos escolares da rede pública. As escolas participantes devem incluir no projeto político pedagógico escolar os temas das atividades em saúde desenvolvidas no Programa, de modo a atender às expectativas dos professores e escolares. Os temas são abordados para facilitar o aprendizado e devem ser adequados às fases do desenvolvimento do escolar. Estudo qualitativo, realizado em 2016, com o objetivo de investigar as percepções dos escolares em relação às atividades desenvolvidas pelo Programa Saúde na Escola em Belo Horizonte, Brasil. A coleta de dados foi realizada utilizado desenho acompanhado de narrativa oral, com participantes na faixa etária de seis a dez anos. Foi possível demonstrar que os escolares puderam receber informações e compreendê-las, a ponto de poder reproduzi-las.
Early Maori literature: The writing of Hakaraia Kiharoa
Authors: Loader Arini
Published: May 2021

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Desain Pembelajaran Qur’an Hadist Model Jerold E. Kemp Berbasis Multimedia Di Madrasah Tsanawiyah
Authors: Asykur Asykur , Zainiyati Husniyatus Salamah , Munawaroh Siti
Published: May 2021

Penelitian ini bertujuan untuk mengetahui pengaruh penerapan desain pembelajaran model Jelord E.Kemp berbasis Multimedia mata pelajaran al-Qur’an hadist dalam  meningkatkan minat belajar siswa di MTs. Miftahul Ulum Timbuan.

Guru mata pelajaran Al-Qur’an hadits  dan siswa kelas VII di jadikan subyek dalam penelitian ini, sedangkan obyek dalam penelitian ini adalah penerapan pembelajaran model Jelord E.Kemp berbasis Mutimedia dalam meningkatkan minat belajar siswa kelas VII mata pelajaran Al-Qur’an hadits. Proses pembelajaran yang masih menggunakan metode konvensional di MTs. Miftahul Ulum Timbuan Kecamatan sarirejo Kabupaten Lamongan menyebabkan rendahnya minat belajar siswa sehingga berakibat pada hasil belajar siswa rendah di bawah batas KKM (≥70). Metode dalam penelitian ini dilakukan menggunakan Penelitian Tindak Kelas (PTK) dengan penerapan pembelajaran menggunakan model Jelord E.Kemp berbasis Multimedia dapat meningkatkan minat belajar siswa kelas VII MTs Miftahul Ulum sehingga hasil belajar yang di peroleh siswa sudah banyak yang mencapai KKM (≥70).  Model Jelord E.Kemp berbasis Multimedia terlaksana dengan baik, Hasil penelitian menunjukkan peningkatan di setiap siklusnya. dapat dilihat dari data  sebelum siklus 63,50%, meningkat menjadi 70,00% pada siklus I dan meningkat menjadi 82,00% pada siklus II.