bluuebunny/crossref_metadata_2025 huggingface dataset:
Optogenetic Globus Pallidus Stimulation Improves Motor Deficits in 6-Hydroxydopamine-Lesioned Mouse Model of Parkinson’s Disease
Authors: Di Bisceglie Caballero Sonia , Ces Aurelia , Liberge Martine , Ambroggi Frederic , Amalric Marianne , Ouagazzal Abdel-Mouttalib
Published: April 2023

Excessive inhibition of the external globus pallidus (GPe) by striatal GABAergic neurons is considered a central mechanism contributing to motor symptoms of Parkinson’s disease (PD). While electrophysiological findings support this view, behavioral studies assessing the beneficial effects of global GPe activations are scarce and the reported results are controversial. We used an optogenetic approach and the standard unilateral 6-hydroxydopamine nigrostriatal dopamine (DA) lesion model of PD to explore the effects of GPe photostimulation on motor deficits in mice. Global optogenetic GPe inhibition was used in normal mice to verify whether it reproduced the typical motor impairment induced by DA lesions. GPe activation improved ipsilateral circling, contralateral forelimb akinesia, locomotor hypoactivity, and bradykinesia in 6-OHDA-lesioned mice at ineffective photostimulation parameters (532 nm, 5 Hz, 3 mW) in normal mice. GPe photoinhibition (450 nm, 12 mW) had no effect on locomotor activity and forelimb use in normal mice. Bilateral photoinhibition (450 nm, 6 mW/side) reduced directed exploration and improved working memory performances indicating that recruitment of GPe in physiological conditions may depend on the behavioral task involved. Collectively, these findings shed new light on the functional role of GPe and suggest that it is a promising target for neuromodulatory restoration of motor deficits in PD.
A Ray Tracing Model for Electron Optical Imaging in Electron Beam Powder Bed Fusion
Authors: Renner Jakob , Grund Julian , Markl Matthias , Körner Carolin
Published: April 2023

The recent success of the process monitoring method Electron Optical Imaging, applied in the additive manufacturing process Electron Beam Powder Bed Fusion, necessitates a clear understanding of the underlying image formation process. Newly developed multi-detector systems enable the reconstruction of the build surface topography in-situ but add complexity to the method. This work presents a physically based raytracing model, which rationalises the effect of detector positioning on image contrast development and masking. The model correctly describes the effect of multiple scattering events on vacuum chamber walls or heat shields and represents, therefore, a predictive tool for designing future detector systems. Most importantly, this work provides a validated method to compute build surface height gradients directly from experimentally recorded electron-optical images of a multi-detector system without any calibration steps. The computed surface height gradients can be used subsequently as input of normal integration algorithms aiming at the in-situ reconstruction of the build surface topography.
Striae Distensae: Clinical Results and Evidence-Based Evaluation of a Novel 675 nm Laser Wavelength
Authors: Verdelli Alice , Bonan Paolo , Fusco Irene , Madeddu Francesca , Piccolo Domenico
Published: April 2023

Background: A current popular aesthetic problem, especially among younger women, is striae distensae (SD), also referred to as “stretch marks.”. Aim: The potential use of the 675 nm laser has been investigated in the treatment of SD. Methods: Patients underwent three sessions of the 675 nm laser with a 1-month interval between sessions. A total of three sessions were performed. The Manchester Scar Scale was used to assess stretch mark changes, and the mean scores related to each parameter at baseline and 6M FU after the last treatment session were measured. A clinical photographic evaluation was performed to show the aesthetic improvement of SD. Results: The patients’ treated areas were the abdomen, thighs, buttocks, and breasts. Mean scores related to each Manchester Scar Scale parameter, with their relative percentage change, at baseline and 6M FU after the last treatment session were significantly improved. The total mean Manchester Scar Scale score significantly diminished from 14.16 (±1.30) to 10.06 (±1.32) at 6M FU (p < 0.01). The clinical photographs showed promising aesthetic SD improvement. Conclusions: 675 nm laser therapy demonstrated a good tolerance for the treatment of stretch marks applied to various body areas preventing any discomfort for the patient and with a significant improvement in skin texture.
Chondroma Arising from the Temporomandibular Joint: A Case Report
Authors: Hijiya Masayoshi , Kono Masamitsu , Okuda Katsuya , Tamagawa Shunji , Iyo Takuro , Kinoshita Tetsuya , Sakatani Hideki , Hiraoka Masanobu , Kojima Fumiyoshi , Murata Shin-Ichi , Hotomi Muneki
Published: April 2023

Periarticular chondromas are common in the humerus and femur but rarely occur in the temporomandibular joint. We report a case of a chondroma in the anterior part of the ear. One year prior to his visit, a 53-year-old man became aware of swelling in the right cheek region which gradually increased in size. In the anterior part of the right ear, there was a palpable 25 mm tumor, elastic and hard, with poor mobility and without tenderness. A contrast-enhanced computed tomography CT showed a mass lesion with diffuse calcification or ossification in the upper pole of the parotid gland and areas of poor contrast within. A magnetic resonance imaging showed a low-signal mass lesion at the parotid gland with some high signals in both T1 and T2. Fine-needle aspiration cytology did not lead to diagnosis. Using a nerve monitoring system, the tumor was resected with normal tissue of the upper pole of the parotid gland in the same way as for a benign parotid tumor. Distinguishing between pleomorphic adenoma, including diffuse microcalcification of the parotid gland and cartilaginous tumors of the temporomandibular joint, may be sometimes difficult. In such cases, surgical resection may be a beneficial treatment option.
Effect of Heat Treatment on the Corrosion Resistance of AlFeCoNiMo0.2 High-Entropy Alloy in NaCl and H2SO4 Solutions
Authors: Peng Yuhan , Zhou Ge , Han Jinke , Li Jianlin , Zhang Haoyu , Zhang Siqian , Lin Li , Chen Lijia , Cao Xue
Published: April 2023

The effects of casting and different heat treatment processes on the corrosion resistance of AlFeCoNiMo0.2 high-entropy alloy in 3.5% NaCl (mass fraction) and 0.5 mol/L H2SO4 solutions were investigated using dynamic potential polarization curves, SEM, XRD, XPS, and other test methods. The results show that in the Cl− environment, the cast alloy has the lowest corrosion current density and higher corrosion resistance compared to the annealed alloy. The elements Al and Mo are severely segregated in the crystal and in the grain boundaries, where galvanic corrosion occurs, and the Al-rich phase produces pitting corrosion in the crystal. The main components of its passive film are oxides of Al, Fe, Co, and Mo, and oxides and hydroxides of Ni. In the SO42− environment, the best corrosion resistance is achieved in the 900 °C annealed state of the alloy. Electrochemical test results show that the alloys all undergo secondary passivation, producing two successive product films to protect the metal matrix. Preferential corrosion areas are concentrated in the molybdenum-rich grain boundaries and nearby dendritic regions, reducing the corrosion resistance of the alloy. The main components of the passive film are oxides of Al and Mo; oxides of Fe, Co, Ni; and hydroxides. The Mo element in the passive film prevents the activated dissolution of Fe and produces the protective component MoO3, which inhibits the dissolution of the alloy and improves the stability of the passive film. The presence of Mo elements increases the selective dissolution of Fe, and the aggregation of Mo elements at grain boundaries after annealing weakens the corrosion resistance of the alloy and leads to the dissolution of the passive film. The main components of the passive film are oxides of Al and Mo; oxides of Fe, Co, Ni; and hydroxides.
The Correlation between Texture Evolution and Recrystallization Behavior during Rheologic Forming of 2195 Al–Li Alloy Cylindric Shell
Authors: Wang Xiaona , Xiong Wei , Zheng Ying , Zhang Jin
Published: April 2023

Spinning extrusion forming (SEF) is a type of rheologic forming process for making complex structured aerospace components, such as ribbed cylindric shells. However, our understanding of the texture evolution and recrystallization behavior during the SEF process is still limited, especially in complex system like the 2195 Al–Li alloy, which is considered to be the ideal material candidate for aerospace vehicles because of its low density and high specific strength. In this study, we investigate the microstructural evolution of a 2195 Al–Li alloy-made cylindric shell component during SEF and subsequent solution treatment and discuss the recrystallization mechanism and its influence on the texture. It is found that particle-stimulated nucleation (PSN) occurs during the SEF process due to a large number of Al2Cu particles, which is responsible for the obvious reduction of texture components during SEF. Additionally, we show that the continuous dynamic recrystallization is responsible for the increased grains with {110} orientation, resulting in relatively stable brass texture components, even in the subsequent solution treatment.
Surveillance of Viral Respiratory Infections in the Neonatal Intensive Care Unit—Evolution in the Last 5 Years
Authors: Bravo-Queipo-de-Llano Blanca , Sánchez García Laura , Casas Inmaculada , Pozo Francisco , La Banda Leticia , Alcolea Sonia , Atucha Jorge , Sánchez-León Rocío , Pellicer Adelina , Calvo Cristina
Published: April 2023

Viral respiratory infections (VRIs) in very low birthweight infants can be associated with high rates of morbidity. The COVID-19 pandemic has exerted a strong impact on viral circulation. The purpose of this study is to report on VRIs during NICU admission in infants below 32 weeks’ gestation and compare data collected between the pre-and post-COVID-19 pandemic periods. A prospective surveillance study was conducted at a tertiary NICU between April 2016 and June 2022. The COVID-19 post-pandemic period was established as being from March 2020 onwards. Respiratory virus detection was performed by real-time multiplex PCR assays in nasopharyngeal aspirates (NPAs). A total of 366 infants were enrolled. There were no statistical differences between periods regarding infants’ birth weight, gestational age, gender distribution, or rates of bronchopulmonary dysplasia. Among the 1589 NPA collected during the pre-COVID-19 period, 8.9% were positive, and among the 1147 NPA collected during the post-pandemic period, only 3% were positive (p < 0.005). The type of viruses detected did not differ according to the study period (pre-COVID19 vs. post-COVID-19): rhinovirus (49.5% vs. 37.5%), adenovirus (22.6% vs. 25%), and human coronavirus (12.9% vs. 16.7%). SARS-CoV-2 was only detected in one patient. In conclusion, the viral profile causing VRI during the pre-COVID-19 and post-COVID-19 era was similar. However, the total number of VRI dropped significantly, most probably due to the global increase in infection prevention measures.
Managing the “Sword of Damocles” of Immunosuppression: Prevention, Early Diagnosis, and Treatment of Infectious Diseases in Kidney Transplantation
Authors: Cacciola Roberto , Delbue Serena
Published: April 2023

The careful tailoring of the most appropriate immunosuppressive strategy for recipients of a kidney transplant (KT) regularly faces a risk of complications that may harm the actual graft and affect patient survival [...]
Challenges to the Practice of Good Governance in Urban Land Use Planning: The Case of Two Selected Ethiopian Towns
Authors: Udessa Fraol , Adugna Dagnachew , Workalemahu Liku
Published: April 2023

The main objective of urban land management is to support efficient land use and supply tracking techniques. The various decision-making stages of the planning process should allow urban land management affected by development projects to participate. In the towns of Gelan and Lega Tafo Lega Dadi, this study attempted to assess the difficulties in the practice of urban land use planning from a governance perspective. To find the gap in land use planning descriptive data analysis was used. Both qualitative and quantitative research techniques were employed. Data were collected using surveys, interviews, focus groups and secondary sources. Descriptive analysis was then used to examine the results. The research showed that citizens’ preferences or existing urban land rights were not taken into account throughout the process of infrastructure construction and urban growth. In addition, urban land expropriation occurred without sufficient consultation and agreement with affected parties. Urban land valuations and property compensation did not represent market values. Urban zoning and law also have not kept pace with urban growth, to control urban sprawl, protect cultural monuments and heritage regions and prevent the spread of informal settlements in metropolitan areas. The general conversion of the land use planning did not exist before the demand from the municipal actors. Last, but not least, the process of obtaining a building permit was lengthy and expensive, and in places of informal tenure, there was no viable concept of protecting urban tenure.
Body and senses in the production of cultural meaning: from Middle Ages to TV series, films and video games
Authors: Rodríguez Gerardo , Miranda Lidia
Published: April 2023

In  medieval  times,  the  literary  nature  of  the  works,  including  written  ones,  were  determined  by  contextual  elements  such  as  the  acoustic  and  momentary channel of communication along with the domain of gestur-al, instrumental and vocal codes. These elements conditioned writers and performers when they improved and perfected their capacities and perfor-mance, on which the message as a whole depended. Today the media and entertainment  industry  also  use  complex  and  rich  connections  between  verbal and visual signs to produce highly symbolic messages through im-aginary re-enactments of the past. The wide range of discursive productions of the Middle Ages can be ana-lysed through the study of the elements and factors that become carriers of meanings and the way in which they do so. We consider that a comparable perspective is also suitable for contemporary semiotic practices that, when interpreting documentary sources of various types and incorporating them into suitable fictional formats for the general public, constitute playful re-configurations of the historical, literary and fantastic Middle Ages. Accordingly,  this  paper  attempts  to  examine  certain  components  of  mass  culture  which  have  transformed  narratives,  characters  and  fictional  worlds,  distinctive  of  the  Middle  Ages,  into  communicative  and  semiotic  practices reinterpreting historical and literary texts as a way of reflecting on people, social life and its problems in the present world. It starts from con-sidering  that  semantic  plurality  and  diachronic  bases  of  the  idea  of  body  and senses enable an interdisciplinary and comparative study, in order to understand  their  historicity,  their  ideological  effect  and  the  innumerable  aesthetic possibilities which they promote in different areas of culture. The reflections take into account the bodily and sensory aspects of the Middle Ages selected by series, films and video games with an impact, as signifi-cant elements, on current cultural orientations and attitudes.
Beyond Mona Lisa’s smile: A theoretical approach to the persuasion of likeness in the digital image
Authors: Haase Fee-Alexandra
Published: April 2023

In  this  article  we  discuss  the  digital  image  as  a  form  of  representation  of  likeness  in  the  digital  environment.  The  English  word  likeness  entails  the meaning of similarity that in the theory of rhetoric constitute persua-siveness. Likeness is an implicit and often taken for granted quality of the communicative performance of digital media. While the term image is a ty-pological classification, semiotic relations of the transfer of meaning can be described with the terms icon and simulacrum. We show their presence in the digital environment tracing their tradition of their function regarding the establishing of likeness to philosophical ideas. We exemplify with the case of the digital images as derivations from the portrait Mona Lisa that the  appearance  as  an  image  of  all  what  is  displayed  on  the  screen  consti-tutes the specific likeness of digitality. The persuasiveness of digital images is in line with the theory of rhetoric in an exaggerated presence of the im-age as source of aesthetic perception with the sense of sight of the viewer.
A semiotic analysis of representations of maids in Greek movies of the 1950s and 60s
Authors: Bardakis Thomas
Published: April 2023

A  variety  of  semiotic  codes,  for  example,  proxemics,  kinesics,  dress  code, verbal code, usually construct specific representations in audiovisual culture. This paper explores the semiotic systems in synergy which seem to lead to consolidation of the social representations of maids in pop culture texts, such as Greek movies in the 1950s and 60s (the old Greek cinema era). The research questions explore the social representations which have been constructed and the ways in which the verbal and non-verbal signs of the maids can lead to the consolidation of their social image or even to a myth construction based on specific ideological perspectives. So, how do maids act  in  Greek  movies  in  the  1950s  and  60s?  What  does  their  performance  signify? A semiotic analysis will  examine all these questions through semiotic codes in those multimodal texts (Greek movies), selected from the field of the historically Greek pop culture texts. These verbal and non-ver-bal codes work coherently to translate the depiction of Greek society and culture and to convey connotative meanings.
Justicia social en Vietnam: Perspectiva y práctica
Authors: Nguyen Tri Minh , Le Thanh Hoa
Published: April 2023

El tema de la justicia social es un tema fundamental de cada época y tiene un gran significado de actualidad porque se plantea junto a la existencia humana, asociada a los sueños y aspiraciones hacia una vida bonita y feliz. Después de todo, el objetivo del crecimiento económico es servir a las personas, el sujeto del desarrollo, de manera justa y progresiva. Porque "los humanos, al dominar en última instancia su existencia social, también están dominando la naturaleza, dominándose a sí mismos y convirtiéndose en hombres libres" (Marx & Engels, 1995, p. 333). Se confirma además en el Informe sobre Desarrollo Humano de las Naciones Unidas (1995) cuando dice: “¿qué significa desarrollo sin tener en cuenta la vida humana?”. Después de todo, el propósito del desarrollo económico es sólo un medio para servir al desarrollo humano. Son las personas las que crean las condiciones, aprovechan las oportunidades y las convierten en una fuerza impulsora para alcanzar sus objetivos de desarrollo, lo que a su vez promoverá el desarrollo socioeconómico. En el proceso de integración internacional, Vietnam ha implementado activamente políticas para lograr la justicia social y ha logrado ciertos resultados, contribuyendo a mejorar el nivel de vida de todas las personas. Hay ciertas limitaciones que deben abordarse para lograr la justicia social en toda la vida social. El artículo analiza los puntos de vista y las prácticas de implementación de la justicia social en Vietnam, proponiendo así soluciones para implementar efectivamente la justicia social en Vietnam hoy.
Some Issues of Ethnic Problems of Rinoseptoplasty in Various Populations: A Literature Review
Authors: Тулебаев Р.К. , Русецкий Ю.Ю. , Махамбетова Э.А. , Аженов Т.М.
Published: April 2023

За последние годы население земного шара насчитывает около ста разных этнических групп с межгрупповыми различиями, и почти каждая из них обладает особыми анатомическими и функциональными особенностями, а также своим представлением о физиологических функциях носа и, конечно, суждением о форме красоты. В настоящее время известен специальный раздел физической антропологии, изучающий географические вариации морфологических, физиологических и биохимических показателей здорового человеческого организма, – этническая антропология. Все вышеизложенное подтверждает чрезвычайную актуальность данной проблемы, отражающую некоторые современные вопросы эстетической ринопластики и нерешенные этнические проблемы в различных популяциях населения.

In recent years, the world’s population has numbered about a hundred different ethnic groups with intergroup differences (Liao W.C., 2007) and almost each of them has special anatomical and functional features, as well as its own idea of the physiological functions of the nose and, of course, a judgment about the form of beauty. Currently, there is a special section of physical anthropology that studies geographical variations in morphological, physiological and biochemical parameters of a healthy human body known as ethnic anthropology. All of the above confirms the extreme urgency of this problem, reflecting some modern issues of aesthetic rhinoplasty and unresolved ethnic problems in various populations.
Voltage Dependent Profiles of the Surface States and Series Resistance (Rs) in the Al-(Cd:ZnO)-pSi Schottky Diodes (SDs) Utilizing Voltage-Current (IV) Characteristics
Authors: DELEN Neslihan , TAŞÇIOĞLU İlke , ALTINDAL YERİŞKİN Seçkin , ÖZBAY Akif
Published: April 2023

In this work, the main electronic parameters of the performed Al-(CdxZn1-xO)-pSi Metal/Interface-layer/Semiconductor (MIS) type Schottky Diodes (SDs) were investigated by utilizing IV characteristics at 300 K. The (CdxZn1-xO) interfacial layer was grown on the pSi wafer by utilizing the sol-gel technique. Ideality-factor(n), potential barrier ФBo, Rs, shunt resistance (Rsh), and rectification rate (RR) (Iforward/Ireverse) values were calculated based on thermionic emission (TE) theory and Cheung function between -4.5V and 4.5V. There parameters also varied for the samples with different doping ratios. Energy-dependent surface state profiles of them were also extracted from the forward bias IV data, and their magnitude was found on the order of 1012eV-1.cm-2 which is very appropriate for the MIS type SD. The values of n, barrier height (BH), ФBo, and RR changed from 4.347, 0.582 eV, 5.74x103 to 5.293, 0.607 eV, 2.83x106. These results show that electronic parameters of these SDs are a strong functions of voltage, calculation method, and the doping rate of the Cadminium (Cd) interfacial layer. The best ratio for Cd: ZnO was determined to be 30%; therefore, this interfacial layer may be used instead of traditional insulator layers to enhance the quality of Metal/Semiconductor (MS) type SDs.
RASIONALITAS MASYARAKAT MENYERAHKAN TANAH DALAM PEMBANGUNAN INFRASTRUKTUR JALAN DI DESA TUNGGUL KECAMATAN PACIRAN KABUPATEN LAMONGAN
Authors: Nur Salam Moh. Rizki
Published: April 2023

The village government of Tunggul does physical development which absolutely requires land. The handover of land in the construction of road infrastructure in the village of Tunggul has been carried out since 2007 until now. However, the process of handing over land cannot be separated from problems. The handover of land involved most of the ownership rights to the land from the residents concerned, while the need for land was increasing. This study aims to identify the objective social and economic conditions of the people who gave up the land, identify the process of handing over the land, and to analyze the rationality of the people who gave up the land. This study uses a qualitative approach with Max Weber's rationality perspective. The results of this study indicate that the socio-economic objective conditions of landowners who hand over land vary starting from education, social status, occupation, income and expenses, needs, and wealth. The process of handing over the land goes through several stages, namely planning, preparation, implementation, and evaluation. The actions of landowners are divided into acts of instrumental rationality and value-oriented rationality actions. The act of instrumental rationality namely the land owner wants a new village road infrastructure and the land owner has the desire to sell his land (profit value). The action of rationality is value-oriented namely the land owner considers religious values ​​as a form of worship and the land owner does good deeds.
KOMPLEKSITAS PEMENUHAN HAK PENYANDANG DISABILITAS YANG BERHADAPAN DENGAN HUKUM DI PENGADILAN TINGGI TANJUNG KARANG
Authors: Fauzi Maghfira Nur Khaliza
Published: April 2023

Pada dasarnya penyandang disabilitas perlu mendapat perlindungan bagi yang berhadapan dengan hukum di pengadilan, terkhusus Pengadilan Tinggi Tanjung Karang. Dalam hal ini perlu melihat lebih mendalam perkembangan hukum dari segi peraturan perundang-undangan saat ini guna menjamin hak-hak penyandang disabilitas dan juga pemenuhan hak pada aksesibilitas fisik dan non fisik seperti sarana dan prasarana gedung yang harus memadai, atau bahkan karena sumber daya pegawai, panitera, dan hakim di pengadilan yang perlu memahami terkait dengan berbagai isu disabilitas. Penelitian ini adalah penelitian hukum yuridis-normatif yang ditujukan untuk menemukan dan merumuskan argumentasi hukum, melalui analisis terhadap pokok permasalahan. Teknik pengumpulan bahan hukum dilakukan dengan studi kepustakaan dan telaah lapangan. Pendekatan yang digunakan adalah perundang-undangan (statute approach), untuk menalaah aturan hukum yang berlaku terkait dengan disabilitas, untuk melihat ketentuan peraturan perundang-undangan dan konsepsi teoritik mengenai disabilitas dengan realitas empirik pemenuhan hak penyandang disabilitas di Pengadilan Tinggi Tanjung Karang. Hasil penelitian menunjukkan bahwa berdasarkan parameter Peraturan Pemerintah Nomor 39 Tahun 2020 tentang Akomodasi Yang Layak Untuk Penyandang Disabilitas Dalam Proses Peradilan, bahwa  aksesibilitas fisik dan non-fisik di Pengadilan Tinggi Tanjung Karang telah terpenuhi dengan baik, yaitu telah memiliki fisik infrastruktur khusus dan alat bantu yang memudahkan penyandang disabilitas dalam mengakses seluruh area publik di pengadilan. Sementara aksesibilitas non fisik bahwa para pegawai pengadilan sudah diberikan pelayanan teknis mengenai pengetahuan dan etika cara melayani penyandang disabilitas, dan kini sudah mulai memahami pelayanan hukum bagi itu penyandang disabilitas.
FAKTOR-FAKTOR YANG MEMPENGARUH MINAT MASYARAKAT MEMBAYAR ZAKAT PROFESI PADA BAZNAS KABUPATEN TAPIN
Authors: Karimah Husna
Published: April 2023

BAZNAS Kabupaten Tapin Mempunyai kemampuan besar untuk menghimpun dana Zakat profesi namun saat ini dana yang terhimpum di BAZNAS Kabupaten Tapin masih sangat sedikit yang tidak lepas dari minat masyarakat itu sendiri. Tujuan penelitian ini merupakan untuk mengetahui apakah aspek pengetahuan, kepercayaan, pendapatan serta peraturan bupati mempengaruhi secara simultan serta parsial terhadap minat masyarakat membanyar zakat profesi pada BAZNAS Kabupaten Tapin. Penelitian ini merupakan penelitian lapangan memakai pendekatan kuantitatif. Dalam penelitian ini sampel yang digunakan merupakan muzakki BAZNAS Kabupaten Tapin sebanyak 35 orang. Hasilnya menunjukkan bahwa variabel pengetahuan, kepercayaan, pendapatan serta peraturan bupati secara bersama-sama memiliki pengaruh signifikan terhadap minat masyarakat membayar zakat dengan signifikasi  0,000 <  0,05. Sedangkan secara parsial faktor pengetahuan tidak berpengaruh signifikan terhadap minat berzakat dengan nilai signifikasi 0,620 > 0,05. Variabel kepercayaan secara parsial berpengaruh signifikan terhadap minat berzakat dengan nilai signifikasi 0,010 < 0,05. Variabel pendapatan secara parsial tidak berpengaruh significan terhadap minat masyarakat membayar berzakat dengan nilai signifikasi 0,316 >  0,05 dan variabel peraturan bupati secara parsial berpengaruh signifikan terhadap minat berzakat dengan nilai signifikasi 0,006 < 0,05.

 

Kata kunci:  Kepercayaan, pengetahuan zakat, pendapatan, peraturan bupati dan minat berzakat.
CATCH UP IMMUNIZATION : PENERAPAN IMUNISASI KEJAR DALAM MENGATASI PENURUNAN CAKUPAN IMUNISASI ANAK PADA ERA NEW NORMAL (STUDI KASUS DI KOTA BANDAR LAMPUNG)
Authors: Kusworo Daffa Ladro
Published: April 2023

Abstrak : Pencegahan penyakit berbahaya pada anak diberikan melalui gerakan program imunisasi. Secara esensial, prioritas pelayanan kesehatan oleh pemerintah menjadi catatan penting dalam rangka pencapaian Sustainable Development Goals (SDGs) di tahun 2030, melalui transformasi kebijakan dan langkah-langkah alternatif. Namun saat ini, masih didapati hambatan dalam  pelaksanaan imunisasi dari berbagai perspektif, baik pembatasan pelayanan kesehatan di puskesmas dan kecemasan masyarakat terhadap penularan covid-19. Konsekuensinya, jumlah angka cakupan imunisasi rutin pada anak juga berpengaruh. Degradasi perolehan imunisasi memerlukan transformasi strategis sebagai langkah proaktif terhadap aspek pelayanan kesehatan, disertai dengan kepatuhan terhadap protokol kesehatan. Pemberlakuan catch up immunization (imunisasi kejar) melalui pemetaan pertimbangan risiko diharapkan dapat mengatasi ketertinggalan imunisasi anak di daerah. Penelitian ini menggunakan metode penelitian hukum normatif dengan pendekatan peraturan perundang-undangan dan studi kepustakaan, serta menggunakan analisis deskriptif dalam pengelolahan data kualitatif dengan penerapan metode deduktif. Hasil penelitian ini menunjukkan bahwa perlunya adaptasi terhadap kondisi pada era new normal, terkhusus aspek pelayanan imunisasi di puskesmas melalui perwujudan catch up immunization dan peningkatan teknis imunisasi keliling, guna mencapai target cakupan imunisasi rutin pada anak di daerah.
EXTENDED SPECTRUM BETA-LACTAMASE (ESBL) PRODUCING PROTEUS SPECIES ISOLATED FROM CLINICAL SPECIMENS FROM SELECTED HOSPITALS IN JIGAWA STATE, NORTH-WEST NIGERIA
Authors: SO Obadire , Mitsan O  , OO Odewusi , Ige IP  , DO Ugbomoiko , OC Oke
Published: April 2023

Proteus species are found in multiple environmental habitats, including long-term care facilities, hospitals, and can also cause both community and nosocomial infections. For a long time, Proteus was known to be susceptible to beta-lactam antibiotics but nowadays they become resistant. Hence, this study aims to determine the prevalence, antibiotic susceptibility pattern of extended spectrum beta lactamase (ESBL) producing Proteus species across Jigawa State, Northwest Nigeria. 1854 different clinical specimens were analysed of which 191 Proteus species were isolated through standard biochemical tests and used for this study from selected hospital between November, 2021 to August, 2022. Modified Kirby-Bauer disk diffusion method was used to test the susceptibility of the Proteus isolates to nine different antimicrobial agents. Double Disc Synergy Test (DDST) was used for phenotypic detection of ESBL in isolates. The prevalence of ESBL producing Proteus mirabilis was 11.8%. None of the Proteus vulgaris isolates in this study was found to be ESBL producers. Male patients were infected with more ESBL producers than those from female counterparts (Male vs Female; 12.5% vs 4.8%). Proteus mirabilis were observed to be significantly more susceptible to Ampicillin (P= 0.003), Gentamycin (P=0.024) and Cotrimoxazole (P=0.014). All ESBL producing Proteus mirabilis were resistant to three or more classes of antibiotics used in this study. This study reveals the occurrence of ESBL producing Proteus species in this environment. All the ESBL producing Proteus mirabilis encountered in this study exhibited multidrug resistance. Prudent use of antimicrobial agents is advocated in order to tame the trend.
RISK-BASED QUALITY CONTROL IN THE SURGICAL PATHOLOGY LABORATORY; BRIEF REVIEW AND DEVELOPMENT OF AN INDIVIDUALIZED QUALITY CONTROL PLAN
Authors: Erdoğan Bahattin , Çivi Çetin Kısmet
Published: April 2023

One of the most important tools for reducing or preventing diagnostic errors in the surgical pathology laboratory is the establishment of a quality management system. Risk analysis and quality assurance are important components to ensure the sustainability of the quality management system. Quality assurance ensures the integrity of program design and includes interrelated activities quality control and quality monitoring-evaluation programs. Risk-based thinking is expressed as the planning of risks and how they should be managed by determining the possible dangers and risks in achieving the determined goals and objectives, using the available information systematically. Laboratories must identify and carry out a large number of interrelated activities to maintain their functions effectively. To achieve its goals, it must demonstrate the ability to measure and evaluate process performance, as well as to demonstrate the effectiveness of past decisions, along with improving operational effectiveness and efficiency. With a successful quality management process, the reliability of laboratory results can be increased. In this study, our objective was to develop a roadmap for the detection, monitoring and minimization of diagnostic errors in the surgical pathology laboratory, in line with the views of international regulatory organizations, to develop a quality plan based on risk management that covers the entire analytical cycle. It is not possible to discuss the quality control of laboratories without accepting the possibility of error in surgical pathology. Investing in continuing medical education and patient safety, as well as the training of new pathologists with a critical view to reducing errors is an imperative way to improve the practice of pathology.
IMMUNOSTIMULANT AND FREE RADICAL SCAVENGING STUDIES OF GANODERMA APPLANATUM
Authors: Divakar Madhu. , Joy Lins Mary
Published: April 2023

Abstract: Objective: The present animal experimentation study is planned to screen the immunostimulant efficacy, free radical scavenging potential and the acute toxicity of the bracket fungus, Ganoderma applanatum . Methods: The study analyse the invitro immunostimulant activity by phagocytic index determination using Candida albicans, acute toxicity study by brine shrimp assay and the free radical scavenging activities of G. applanatum solvent extracts. Conclusion: The percentage immunostimulation was found to be 88% for the chloroform-methanol (1:1) Ganoderma applanatum extract (GAE). The free radical scavenging activity studies were performed by utilising invitro model of hydroxyl, superoxide and lipid peroxide radical generating system. Results indicated that GAE at 100 mcg/ml showed 88.1, 89.19, and 81.87 % scavenging activity of hydroxyl, superoxide and lipid peroxide radical respectively. The LC50 was determined using brine shrimp assay method and calculated as 875 mcg /ml. The present study shows that G. applanatum can be utilised as an effective natural supplement to impart immunostimulation.
Mechanisms of deviant behaviour formation in contemporary socio-cultural contexts
Authors: Dobriakov Igor , Liskovsky Oleg
Published: April 2023

Introduction. The article is devoted to the description and analysis of deviant behavior of young people in conditions of intensive development of information and communication technologies that facilitate and simplify the interaction of young people. The relevance is determined by the need to comprehend the importance of new socio-cultural factors in the formation of deviant behavior in order to improve the measures of its prevention and correction.

The aim of the research is to characterise the role of the supervalue idea in the development of destructive forms of deviant behavior and to illustrate its manifestations in the contemporary socio-cultural context.

Methodology and methods of the research. The methodological basis of the study is a combination of theories and concepts of deviant behavior that form the subject area of deviantology. General scientific methods used for generalisation and systematisation of information on deviant behavior, its forms and their manifestations are applied. The research material covers cases of deviant behavior of adolescents and young people.

The result of the research is a description and characterisation of the contemporary socio-cultural context associated with changes in norms of behavior. The main reasons are identified as the current growing anomie, the consequences of the information and communication revolution and the subsequent generation gap. The authors emphasise the high level of basal anxiety, currently leading to emotional tension, which contributes to the formation of supervalues. Various forms and manifestations of these ideational and affective abnormalities are described, including the emergence of ideas with signs of extremism, and the rise of auto- and heterogression. Understanding the mechanisms of these tendencies is of theoretical and practical importance for the prevention of deviant behavior, as well as for counselling, psycho-corrective and psychotherapeutic work.
Destructive social media activities aimed at promoting suicidal behavior among minors: counteracting measures
Authors: Puchnina Margarita , Puchnin Aleksandr
Published: April 2023

The article is devoted to such a socially significant problem as suicide of minors. It provides statistics for the last three years on the number of suicides and attempts at committing them. Emphasis is placed on the role of social networks in thesuicidal behavior of minors. The background to the issue is briefly reviewed. The activity of «death groups» in VKontakte is analysed, its two stages are determined: involvement and direct suicide inducement, as well as some peculiarities of the work. The authors describe a game that involves minors for the purposes of suicide and self-harm. A new Internet trend - dangerous challenges on the popular video hosting site TikTok - is discussed. The authors present the mechanism of the social networks themselves, as well as the activity of destructive organisations on them. The possibility of reporting (leaving a complaint) is explained, and deadlines for dealing with such appeals are given. The chronological order of counteracting destructive content in these social networks is outlined. Some examples of preventive activities, which are currently being carried out with great success, are given. Much attention is paid to the involvement of civil society institutions in prevention activities, and it is recommended to develop and support the cybervolunteer movement. The paper discusses the need for parents themselves to monitor teenagers’ social networks and messengers, as well as the importance of their information literacy.
On the problem of involving minors in destructive activities through information and communication technologies
Authors: Taganova Anna , Lapsar Margarita
Published: April 2023

Introduction. The modern development of the personality, the stages of its socialization and the peculiar perception of social norms of behavior are realized in conditions of active processes of informatization and computerization. The related changes in everyday life, communication, organization of activities bring both constructive and destructive factors. It is difficult to dispute the fact that information and communication technologies have become so firmly established in the life of a modern person that they are no longer characterized as a way to simplify activities, but as a complete environment for the formation of personal characteristics and the implementation of communication. This situation leads to the fact that active users of information and communication technologies begin to be affected by content of various content, including destructive one. Minors are the most vulnerable group of users of such technologies due to their personality and age peculiarities. In this regard, the law enforcement system and public organizations are faced with the task of creating safe conditions for minors to use the possibilities of the information and communication environment.

Objective. This study was carried out to substantiate the relevance of studying the psychological factors of a subjective and objective nature that contribute to the involvement of minors in destructive activities through information and communication technologies.

Methodology, methods, techniques. Universal for any field of scientific cognition, system-structural and qualitative approaches were used to conduct research on the chosen topic. The research methodology is based on modern scientific, methodological and socio-psychological characteristics of formation and development of the destructive behavior of minors.

Results. The results of the conducted scientific research indicate the need for a comprehensive study of the problem and the preparation of scientific support for preventive activities to prevent deviant behavior of minors.

Scientific novelty. The analysis of the scientific literature led to the conclusion that the existing insufficient development of the problem chosen for the study, which substantiated the scientific novelty of the results presented in this article. The relevance of the upcoming research is revealed, reflecting the need for their implementation.

Practical significance. The practical significance of the study lies in the fact that today, due to the insufficient development of this topic, there are certain difficulties in the implementation of prevention of deviant behavior among minors, and the results obtained during the study will fill the existing gap and increase the efficiency of work with minors to prevent their involvement into deviant activities.
Organisational and pedagogical conditions for the formation of moral values in cadets of the ministry of internal affairs of the Republic of Kazakhstan to prevent corruptive behavior
Authors: Fedotova Elena
Published: April 2023

In the era of law enforcement reform, it is very important to pay close attention to the quality and content of the personal structures of graduates of departmental educational institutions. The basis of the philosophy of policing in Kazakhstan today is the idea of a helpful police officer who fully meets the needs of society and the requirements of the state. One of the main requirements for police in modern Kazakhstan is resistance to corruption. The author’s idea is that the formation of moral values in cadets during their training in a departmental university can become a qualitative basis for the prevention of corruption offences of police officers in the future. The author considers some shortcomings of departmental education that hinder the process of developing moral values, and describes the conditions under which this process can take place more effectively. In addition, the author describes a model for the formation of moral values in cadets, which can be used in the educational process of the university. In describing the model the author lists criteria and indicators that will help to assess the degree of formation of moral values in cadets and conduct qualitative monitoring of the results of the work on their formation.
INVESTIGATION OF BRIDGES DAMAGED AND DESTROYED BY EXPLOSIONS
Authors:   M.P. Shulgin State Road Research Institute State Enterprise - DerzhdorNDI SE, Kyiv, Ukraine, Borysenko Maksym , Zavhorodniy Serhii ,   M.P. Shulgin State Road Research Institute State Enterprise - DerzhdorNDI SE, Kyiv, Ukraine, Kaskiv Volodymyr ,   M.P. Shulgin State Road Research Institute State Enterprise – DerzhdorNDI SE, Kyiv, Ukraine
Published: April 2023

Introduction. Conducting inspections of destroyed and damaged bridges is crucial for the process of restoring these structures as the quality and objectivity of the decisions made during the design and construction works will depend. Problem Statement. In the course of Ukraine’s confrontation with the full-scale armed offensive of the russian federation, hundreds of bridges on roads of various administrative subordination were destroyed and damaged. The legislative and regulatory framework in Ukraine did not provide an algorithm for conducting inspections and restoration of destroyed buildings and structures at the time of the introduction of martial law. Purpose. The purpose of the article is to highlight the experience of conducting inspections of destroyed and damaged bridges, as well as to highlight changes in legislation after the introduction of martial law aimed at regulating the processes of fixing, inspecting and restoring damaged and destroyed transport facilities. Results. The article presents the results of inspections of about 40 damaged and destroyed structures on the roads of national importance in the regions where military operations took place during the martial law in Ukraine. The destruction of bridge structures is affected by various factors such as the nature of the explosion, the design of supports and spans, and the static scheme of the bridge. Conclusions. The experience gained from the inspection of about 40 bridges damaged as a result of the armed invasion of Ukraine by the Russian Federation allows us to draw conclusions in two directions. First, the inspection of structures requires a professional and responsible approach from both the contractors and the balance holders (owners) in terms of formulating the inspection task and accepting the relevant technical documentation based on the inspection results. Secondly, there is a need to develop and update legal, regulatory and technical documents that would take into account the experience gained and be aimed at reducing the potential threat of bridge collapse and reducing the costs of their subsequent restoration.
CALCULATION METHOD FOR ASSESSMENT THE IMPACT OF VEHICLES ON THE AIR ENVIRONMENT
Authors:   M.P. Shulgin State Road Research Institute State Enterprise - DerzhdorNDI SE, Kyiv, Ukraine, Kharytonova Nataliia
Published: April 2023

Introduction. The negative impact of vehicles is primarily occurs not only in big cities and on roads in megacities, but also on public roads with heavy traffic. The specifics of mobile sources of pollution (cars) occurs in their low location, spatial distribution and close proximity to populated areas. All this leads to the fact that motor vehicles create big and persistent zones in which environmental standards of air pollution are exceeded several times. Problem statement. Actually, in Ukraine there are evaluation methods for determining the assessment of the impact on the air environment in the area affected by roads. Gross emissions of pollutants and warming gases from vehicles are determined exclusively by statistical data on fuel consumption by internal combustion engines of motor vehicles of legal entities and individuals. Purpose. Clarify the estimates of gross emissions of pollutants and warming gases in exhaust gases from the vehicles while driving on roads, including the implementation of EURO V European standards, with determination of the objective level of negative impact on the air environment. Materials and methods. Analytical, information-searching. Results. The paper presents the procedure for the evaluation of pollutants and warming gas emissions during the operation of vehicles driving on public roads. Conclusions. The performed analysis will allow us to evaluate the impact on the air environment in the area affected by roads highways by evaluation method, the procedure for assessment the emissions of pollutants and warming gases from vehicles driving on public roads has been determined.
Uma epistemologia para a adaptação da literatura ao cinema
Authors: Dos Santos Márcio Soares
Published: April 2023

Este artigo busca uma aproximação aos processos adaptativos da literatura para o cinema em temos epistemológicos. Seus fundamentos estão em Michel Foucault e Pierre Bourdieu para questões sobre as relações de poder e a produção de bensculturais, e em Jacques Aumont para as relativas ao filme. Utiliza, para exemplificação, Mirad los Lírios del Campo (1947), adaptação argentina para cinema, dirigida por Ernesto Arancibia, do livro Olhai os Lírios do Campo (1938), do autor brasileiro Erico Verissimo. Interessa-se em examinar como a transterritorialidade na adaptação afeta as representações nos dois campos.