bluuebunny/crossref_metadata_2025 huggingface dataset:
Online tools for individual study of specialised vocabulary – selected challenges
Authors:   Uniwersytet Medyczny w Białymstoku, Dudzik Agnieszka , Dzięcioł-Pędich Agnieszka ,   Uniwersytet w Białymstoku
Published: January 2023

The acquisition of lexis is an important part of language learning. It is also a vital component of English for Specific Purposes (ESP) education, as knowledge of specialised vocabulary is considered integral to success in occupation-specific communicative activities. Expanding professional lexis is essential to help ESP learners understand the language and concepts of their academic or professional discipline and achieve specific communication goals. This paper aims to discuss selected challenges of using online tools (which were subjected to a qualitative analysis) to develop specialised lexis at the tertiary level. An outline of difficulties in professional vocabulary learning and a review of the main characteristics of teaching ESP are also included.
Tradycja i nowatorstwo w tworzeniu zdrobnień imion dzieci w świetle badań ankietowych
Authors:   Uniwersytet w Białymstoku, Gawroń Małgorzata
Published: January 2023

The aim of the paper is to analyse diminutives of children’s names indicated by parents in a questionnaire survey, and also to attempt to define modern trends and mechanisms used for making diminutives. A structural classification and a frequency analysis of the collected diminutives are offered, which allow for determining the use of traditional and modern word-formation models. The investigation of the questionnaire data enables collecting various diminutives derived from one name.
Rozwój polskiej myśli glottodydaktycznej nad nauczaniem języka do celów medycznych
Authors:   Katolicki Uniwersytet Lubelski Jana Pawła II, Oczko Paulina
Published: January 2023

The subject of the present text is the Polish language of medicine (medical), while the aim is to present and discuss the concepts of teaching medical Polish developed over the last 50 years. The work is both a review and a summary of the achievements of Polish language glottodidactics to date. The analysis is based on both academic texts on linguistic and subject-related education, and on the teaching of specialist (medical) language, as well as on glottodidactic materials from 1975–2022. The review of previous concepts of teaching medical Polish leads to the conclusion that the greatest emphasis was placed on mastering professional terminology and grammatical structures characteristic of the professional speciality, as well as developing reading and speaking skills. The necessity of teaching the competence of working with text, especially its stylistics, was also recognised.
Implementation of The Siracusa Principles as Foundations for Reformulation of Social Restriction Policies in Public Health Emergencies
Authors: Harris Rahadyan Fajar , Simanjuntak Natalia Carolina
Published: January 2023

The purpose of this research is to implement the Siracusa Principles as the basis for the formulation and evaluation of public policies that have the potential to restrict people's rights and freedoms during social restrictions. This research uses the statutory and conceptual approaches of normative juridical methods as instruments of analysis. The findings of this paper include 667 cases of human rights violations released by LBH Jakarta throughout 2020. There are result of the government's social restriction policy to suppress COVID-19 transmission. Although Article 4 of the International Covenant on Civil and Political Rights (ICCPR) allows governments to restrict certain rights during public emergencies that threaten the life of the nation, states are not allowed to arbitrarily restrict people's rights and freedoms. Therefore, a mechanism is needed that can set restrictions on public rights in a balanced manner. In this regard, the Siracusa Principles can be implemented as a basis for the formulation of public policy through human rights due diligence and evaluating the government's compliance in implementing its policies. The novelty of this paper contains comprehensive discourses and recommendations in reformulating social restriction policies that are less friendly to human rights protection through restrictions on rights proportionally and internationally, and allow for the existence of check and balances mechanisms for the course of public policy. Therefore, with the implementation of the Siracusa Principles can be the basis for establishing restrictions on rights proportionally in order to develop policies of social restrictions and health quarantine that are more friendly to human rights protection and can minimize the occurrence of policy formulation errors that have the potential to violate human rights.
Technical Intelligence and Security Management within the Nigerian Territorial Waters: The Nigerian Navy Challenge
Authors: Nte Ngboawaji Daniel , Enoke Brebina Kelvin , Abubakar Ilyasu
Published: January 2023

With the world becoming a more volatile place and certainly high - threat environments becoming too far and dangerous to send personnel, the insufficiency of human intelligence has placed a greater stress on technical aids in gathering intelligence. Technology has allowed the acquisition of intelligence to rely less on human intelligence. The progeny of modern day equipment - both offensive and defensive has made provision for myriad levels in intelligence gathering. The Gulf of Guinea Basin countries rely heavily on their maritime sector for greater per cent of their exports and imports. The Gulf of Guinea is strategic to the development of West African countries and has been characterized by various maritime crimes, thus the need for technical intelligence and surveillance measures by basin countries to enhance the security of the region. Nigeria is a strategic stakeholder in the maritime security around the Gulf of Guinea with her Navy and Nigerian Maritime Administration and Safety Agency as the lead agencies responsible for her maritime security and safety. This work discusses the various leverage and the challenges of modern surveillance equipment to aid the achievement of securing the Nigerian maritime environment by the Nigerian Navy as well as her involvement in several internal security operations in Nigeria.
The Disclosure of a Murder Case Using Fingerprint Identification Method: An Alternative
Authors: Pradityo Randy , Herlambang Herlambang , Rahmasari Helda , Purwo Galih
Published: January 2023

This study aims to identify the function and role of fingerprints as a tool in the disclosures of a crime and the identification of the victim and suspect. It was conducted in the jurisdiction of the Bengkulu Regional Police. Data were collected data by direct interviews and documentation. Data were analyzed using qualitative techniques and then presented descriptively by providing descriptions and explanations in accordance with the problems of the study. The results showed that the function and role of fingerprint identification to scientifically disclose the victim and suspect of a crime was very important. Fingerprint identification functions as a tool or evidence for investigators to first determine and narrow the investigation
Kompleksinės medicininės reabilitacijos poveikis gydant paauglių nespecifinį apatinės nugaros dalies skausmą
Authors:   , Aukštikalnis Tomas
Published: January 2023

Effect of comprehensive medical rehabilitation program on adolescents nonspecific low back pain
Non-invasive subcutaneous hyperthermic laser lipolysis with pulsed 1064nm diode laser for localized fat reduction
Authors: Fasola Elena , Rebecca S Degliuomini
Published: January 2023

Non-invasive subcutaneous hyperthermic laser lipolysis could be an alternative to classic surgical liposuction. In this study the same physician treated 32 patients (22 females and 10 males) mainly in the abdomen and in the trochanteric region for 2 sessions, with specific and well-described settings. This treatment resulted to be extremely successful based on body weight, abdomen circumference, trochanteric circumference, abdomen subcutaneous fat ultrasound, trochanteric subcutaneous fat ultrasound. No adverse events were reported. Non-invasive subcutaneous hyperthermic laser lipolysis represents, therefore, a potential alternative to classic surgery in selected cases.
Populism in a society with an excess of challenges: the threat to democracy or the possibility of its correction?
Authors: Reznik Oleksandr
Published: January 2023

The phenomenon of growing support for populist parties and relevant orientations among the world's population is usually defined as a threat to democracy, social unity, and civic activism. The psychological appeal of populist ideas is based on the human need for collective identity, social cohesion, categorization of social life, predictability and sense of security as well as moral absolutism and support for conspiracy theories. This leads to the spread of confrontational discourse in the public sphere, support for authoritarianism and deepening social cleavages. However, empirical researches show the ambiguous focus of populist orientations in support of anti-democratic ideas. In fact, citizens with populist orientations should not be unambiguously identified with voters of populist parties. Because of its mobilizing potential, populism can make the democratic process more inclusive, as people with populist orientations support deliberative forms of democracy. In some cases, populist mobilization become useful in emergencies, such as the overthrow of an authoritarian regime or resistance to the enemy during war. However, populism can be an obstacle in trying to reform state institutions, as the absolutization of simplistic forms of government and the propensity for authoritarianism common among populists block civic initiative.
Ukraine in a demographic dimension: the crisis phenomena in sphere of population reproduction in 1991–2021
Authors: Pribytkova Iryna
Published: January 2023

This paper completes the research triptych dedicated to phenomena of depopulation in Ukraine. Analysis of the crisis phenomena in the domain of population reproduction has been added by characteristics of statistical sources and methodological support of correct analysis of statistical information. The motive power of depopulation was founded on the transformation of the demographic regime completed in Ukraine in the 1970s. Accumulated in the age structure potential of demographic growth due to high fertility in recent times proved to be very near the exhaustion. In consequence of it loss, the natural increase of the population reduced steadily and its transition into natural decrease became inevitable. It has happened in Ukraine in 1991 and coincided in time with the beginning of unpopular market reforms. Though these reforms are regarded as the main cause of losses in the natural increase of the population, in reality the connection of fertility tendencies with the political situation at the beginning of the 1990s is relatively weak. In the present case more deep evolutionary conditionality of population reproduction processes takes place. The transition to the regime of narrowed reproduction has started long before the reforms. A crisis of post transitional fertility has arisen in Ukraine still before the USSR dissolution. Ukrainian people went through three profound crises during soviet period. Each of it was accompanied by demographic crisis in the form of considerable increase of mortality (death-rate) and essential lowering of fertility (birth rate). Today Ukraine is going through fourth demographic crisis: swift shortening of fertility and growth of mortality, dates back to the last decade of XX century and are lasting till now.
The Human, Nonhuman, Inhuman in Cormac McCarthy's The Road
Authors: Changizi Parisa
Published: January 2023

Cormac McCarthy’s summoned gothic realm of terrorizing darkness and bestial hunger in his Pulitzer Prize winning novel The Road (2006) is a spectacle defined by a sweeping sense of loss and a charred landscape. The interplay of the human, the nonhuman, and the inhuman molds the contours of the lived experience in this grey world of dwindling resources. Although this harrowing hell plays quite nicely into our fears of ecological apocalypse, manifesting our anxiety about our total dependency on the natural environment, The Road seems to be mainly preoccupied with the human, good and bad, taking the insolvent earth almost as a donnée. Ultimately, with almost no convincing sign of environmental rejuvenation, humanity’s sole saving grace seems to be the divinity within us; this manifests itself most clearly in the character of the boy, whose status as an archetypal savior figure in the story ties him very closely with the central issues of food and the subsequent moral choice.
“No son delincuentes”. Infracciones, legislación e internamiento de hombres menores de edad (San José, Costa Rica, 1955-1973)
Authors: Izquierdo Vázquez Carlos
Published: January 2023

El artículo analiza las medidas de internamiento de hombres infractores menores de edad. La ley 3260 transformó el tratamiento hacia los menores, la cual busca diferenciarlo del procesamiento de adultos; junto con el Juzgado Tutelar de Menores se encargaron de su defensa legal. Desde la década de 1960 predominaron los jóvenes internados en el Centro de Orientación Luis Felipe González Flores. Los trabajadores sociales asumieron la intervención, el tratamiento y el acompañamiento de los menores retenidos y sus familias. El éxito de las políticas de readaptación y reeducación fue calificado por los abogados y trabajadores sociales como escaso, debido a la falta de presupuesto institucional, las inadecuadas instalaciones de internamiento, la insuficiente cantidad de trabajadores sociales, la ausencia de un centro intermedio y la falta de medidas especializadas de atención.
Poder y literatura en Centroamérica: Sergio Ramírez y Carlos Alvarado
Authors: Molina Jiménez Iván , Díaz Arias David
Published: January 2023

Este artículo analiza la relación entre literatura y política en Centroamérica con base en dos procesos diferentes, pero interconectados. Por un lado, los encuentros que sostuvieron en 2019-2020 el escritor nicaragüense, Sergio Ramírez, y el presidente de Costa Rica, Carlos Alvarado. Por otro, la secuela de esas reuniones, materializada en una propuesta de los expresidentes costarricenses para que la Asamblea Legislativa otorgara a Ramírez la ciudadanía honorífica en 2021. La metodología utilizada consistió en comparar la trayectoria de Ramírez con la de Alvarado y hacer una exhaustiva revisión hemerográfica. Se concluye que Ramírez promovió esos encuentros para contrastar la política democrática de Costa Rica con el régimen autoritario de Nicaragua, y que Alvarado lo secundó para tratar de difundir su producción literaria a escala internacional y compensar su creciente impopularidad como presidente de Costa Rica. Además, se muestra cómo la democracia costarricense, al posibilitar la protesta de los adversarios de Ramírez, jugó en contra de la distinción impulsada por los exmandatarios.
El mar como escenario en la obra literaria de Manuel Sánchez Mármol, escritor mexicano e impulsor de la novela realista en los siglos XIX y XX
Authors: Cerino Kristian Antonio
Published: January 2023

El presente artículo es un acercamiento a la obra narrativa del escritor mexicano Manuel Sánchez Mármol con la finalidad de encontrar vasos comunicantes entre sus cuentos marítimos y otros relatos de la literatura universal, donde el mar se muestra al lector como un gran escenario.

A través de sus cuentos marítimos, Viaje de novios (1905), Oceánida (1904) y El túnel número 12 (1904), se busca este acercamiento a la narrativa de Sánchez Mármol, novelista y cuentista poco valorado en su tiempo e ignorado por la crítica literaria (Sol, 2011). Sánchez Mármol fue considerado un escritor realista y de acuerdo con sus escasos críticos, podría figurar al lado de Benito Pérez Galdós y José Tomás de Cuellar. Por ello, otro de los fines de este artículo, es poner sobre la mesa el nombre de un escritor escasamente estudiado, para su lectura y análisis, por medio del rescate de su obra y su memoria.
Educación sexual en Costa Rica. Tensiones y avances en las primeras décadas del siglo XXI
Authors: Preinfalk Fernández María Luisa
Published: January 2023

En el presente artículo se sistematizan algunos de los acontecimientos más relevantes sucedidos en Costa Rica en el período 2000-2018, en torno al desarrollo de la educación sexual en el sistema educativo formal, con el fin de aportar elementos para comprender el contexto nacional y puntualizar algunos retos que se enfrentan. La metodología utilizada fue la revisión documental de textos producidos en el país y material noticioso nacional en línea. Los hechos que se analizan muestran la complejidad que media en el cumplimiento de este derecho, entretejiéndose intereses políticos, culturales, económicos y de otra índole, que generan nuevos retos para la institucionalidad costarricense.
Batman en Chile de Enrique Lihn: el locus horridus y el espectáculo
Authors: Rojas Pachas Daniel
Published: January 2023

Las novelas de Enrique Lihn enmascaran tras una cultura del espectáculo, actos represivos latentes. La narrativa del autor está cruzada por la presencia de situaciones intolerables generadas por un régimen fascista, el cual se vale de la retórica ideológica y el simulacro, para crear cultos a la personalidad y formas de vasallaje cultural. Batman en Chile se construye como un artefacto que evidencia el locus horridus nacional. El kitsch, como estrategia textual, permite al autor apropiarse del lenguaje y los formatos que deja el detritus de los mass media, a la vez busca evadir un ambiente de censura y control de los discursos. El mundo de la novela es un simulacro de ideologías que se ajustan al modelo americano de vida. Una representación de la realidad chilena del periodo de la guerra fría que expone el espectáculo y los medios de masas como aparatos ideológicos al servicio de las deformaciones del poder y su retórica.
PARENT INVOLVEMENT IN STEM EDUCATION: PRESCHOOL TEACHERS’ ATTITUDES, KNOWLEDGE AND PRACTICE
Authors: Aleksieva Lyubka , Mirtschewa Iliana
Published: January 2023

Early STEM education has a great potential to support children's development in building their knowledge, in designing, discussing and testing ideas and finding solutions to different problems. Teachers have an essential role in the STEM process, but this role is shifted from the traditional leading role to a supportive facilitating role. In order to extend learning beyond the classroom and create positive experiences for children, a key factor is the involvement of parents in this process. Parent involvement could be seriously influenced by the knowledge, attitudes and practices of preschool teachers, and therefore their exploration is very important. It could help for planning and designing more effective training for preschool teachers both during their academic preparation and within qualification courses. Accordingly, this paper presents the results of a study with preschool teachers within the framework of the Erasmus+ European multilateral project "STEM for preschool children and their parents" (PARENTSTEM) (2018-2021). The primary goal of this project was to increase parental involvement in preschool STEM education, focusing on families of lower socioeconomic status. Implementation of project’s objectives aimed to expand the conceptual and pedagogical knowledge of preschool teachers in STEM through conducting various teacher trainings and developing intellectual products. This study attempts to identify teachers' prior knowledge, awareness and attitudes towards the conceptualization and pedagogy of STEM with parental involvement, and to discover the relative influence of the project activities on them. The results of the study demonstrate the need for preschool teacher trainings in the area of parent involvement in STEM, and outline the main points that should be considered in the construction of STEM courses designed for preschool teachers.
Peritoneum, a multifunkcionális hártya
Authors: Ferencz Andrea , Farahnak Khashayar , Bocskai Krisztián , Juhos Krisztina , Fehér Daniella , Csukás Domokos , Blázovics Anna , Szabó Györgyi , Sándor József
Published: January 2023

Összefoglaló.
Bevezetés: Ma már bizonyítékokra épült elvárás, hogy a hasi
műtétek során az atraumatikus műtéti technika, a pontos és teljes
vérzéscsillapítás, az idegen anyagok eltávolítása mellett a peritonealis felszín
mechanikus károsodását, kiszáradását is el kell kerülni. A hashártya kiterjedt
felszínével, különleges szöveti szerkezetével nemcsak fontos szereplője a
normális élettani folyamatoknak, hanem mint a „hasüreg őre” fontos szerephez jut
a gyulladásos folyamatok lokalizálásában, dializáló felszínként is hasznos, és a
daganatok kezelésében teret ad a hipertermiás hasüregi kemoterápiának.

A peritoneum-zsák legnagyobb része a vastag- és a vékonybelet borítja be. A
posztoperatív szövődmények elkerülésére mind a nyitott, mind a laparoszkópos
hasi műtétek során kerülendő a bélállomány kiszáradása, így a rehidrálás ma
rutineljárás. Ismeretes, hogy a bél kiszáradása posztoperatív adhéziók
létrejöttéhez vezet, továbbá a serosa károsodással jár, ez a bélfal
áteresztéséhez, perforációhoz is vezethet. Minden sebészi ajánlás kiemeli a bél
nedvesen tartásának fontosságát, miközben az ezt a nézetet támogató, vagy ennek
hiányát elemző kutatás, valós hatásvizsgálat elenyésző a szakirodalomban.
Közleményünk áttekinti e kérdéskör kórélettani mechanizmusait és sebészi
vonatkozásait, összefoglalja a peritoneum összetett funkcióira vonatkozó
legújabb kutatások eredményeit.

Summary.
Introduction: Not only atraumatic surgical technique, precise
bleeding control, removal foreign materials from the abdomen, but also avoiding
desiccation or mechanical damage of peritoneal surface at abdominal surgery mean
today evidence based expectation. Peritoneum with its extensive surface and
special histological structure represents an important factor in normal
physiological processes, furthermore as “Guard of abdomen” it has an important
role to localise inflammatory reactions, useful as dialysing surface and
provides also possibility for hyperthermic abdominal chemotherapy in tumour
treatment.

Largest part of peritoneal sac covers small intestine and colon. To prevent
postoperative complications it is necessary to avoid desiccation of intestinal
tract at laparoscopic and at open procedures as well – consequently “rehyration”
is a routine recommendation today. Desiccation of intestinal tract results
postoperative adhesions, furthermore damage of serosa will increase permeability
of intestine wall and can result perforation. All the surgical recommendations
suggest keeping intestine moist, whereas there are only a few real studies in
surgical literature to support or to deny this theory. Our study reviews the
pathophysiological and surgical respects of this situation and summarizes the
results of latest researches of combined functions of peritoneum.
Evaluation of Pharmacodynamic interaction between Tinospora Cordifolia Alcoholic extract and Gliclazide : An herb-drug interaction study
Authors: Jirapure Kajal Ajit , Undale Vaishali  Ravindra , Addepalli Veeranjaneyulu
Published: January 2023

Many diabetic people today consume herbs or herbal formulations along with prescription and non-prescription medications which may result in the herb-drug interaction Tinospora Cordifolia, with berberine being one of the most abundant active phytoconstituent widely used as an antidiabetic While Gliclazide is indicated to treat type 2 diabetes mellitus whichacts asan insulin secretagogue .T. Cordifolia is a potent inhibitor of CYP2C9 and Gliclazide is known to be metabolized by this enzyme. Potential Pharmacodynamic herb drug interaction might be possible in case of co administration of both. The pharmacodynamic interaction between TCE and Gliclazide was evaluated on hypoglycemic activity in normal and streptozotocinnicotinamide-induced diabetic rats. The study was conducted in 2 parts viz. acute study and sub-acute study in both normal and diabetic animals. The serum triglyceride level and histopathology of pancreawas performed to assess effect on glucose metabolism and pancreas.FTIR Analysis was also carried out to evaluate the interaction between functional groups. The combination showed pharmacodynamic interaction as reduction the time of onset of action and increasing the duration of action of gliclazide when administered in combination with T. cardiofolia. In FTIR studies of combination showed no physical interaction betweenfunctional groups suggesting both drugs might be acting on the different receptors. The study concludes that the combination of Gliclazide with TCE showed an increase in the hypoglycemic effect as compared to the gliclazide alone in STZ-NIC induced diabetic rats. This might be utilized clinically as a beneficial drug interaction in patients after thorough investigations in clinical studies
Evaluation of the National Center for Health Statistics Data Presentation Standards for Rates From Vital Statistics and Sample Surveys
Authors: Talih Makram , Irimata Katherine , Zhang Guangyu , Parker Jennifer D
Published: January 2023

For the confidence intervals used in the standards for rates from vital statistics and complex health surveys, this report evaluates coverage probability, relative width, and the resulting percentage of rates flagged as statistically unreliable when compared with previously used standards.
Abduktion som alternativ i didaktisk forskning
Authors: Wilhelmsson Linda , Damber Ulla
Published: January 2023

Syftet med artikeln är att belysa hur abduktion kan vara särskilt förtjänstfullt när forskningsintresset är didaktiskt. En av den didaktiska forskningens utmaningar är förutsättningar för vetenskaplig kunskapsproduktion som skapas i relationen mellan teori och praktikens skeenden. En särskild utmaning handlar om att tillgängliggöra didaktisk forskning för verksamma inom skolan och i den undervisning som bedrivs. Abduktion bidrar designmässigt till att reflektion över relationen mellan teori och praktik får en given plats i kunskapsproduktionen och att kunskapsbidraget kan formuleras som didaktiska modeller och begrepp som kan bidra i planering och analys av undervisning. I ett snabbt föränderligt samhälle ställs stora krav på att också utbildning och undervisning ständigt kan omprövas. De företeelser som studeras i undervisning är komplexa vilket skapar särskilda förutsättningar för hur de kan förstås och förklaras. Abduktion kan motverka entydiga förståelser och snäva förklaringsgrunder i forskning om undervisning genom att öppna för kontinuerlig utvärdering och utveckling. Ovanstående samband belyses genom illustrationer från två avhandlingar avseende forsknings-bakgrundens roll, urval och empiri, analysprocess, framställan i text och frågan om hur kunskapsbidrag kan gestalta sig. Diskussionen ägnas framför allt åt forskningens giltighet och tillgänglighet, och hur nyttiggörande av didaktisk forskning kan stärkas metodologiskt med hjälp av abduktion.
STAGING LAPAROSCOPY IS STILL A VALUABLE TOOL FOR OPTIMAL GASTRIC CANCER MANAGEMENT
Authors: SAKAMOTO Erica , RAMOS Marcus Fernando Kodama Pertille , PEREIRA Marina Alessandra , DIAS André Roncon , RIBEIRO JUNIOR Ulysses , ZILBERSTEIN Bruno , NAHAS Sergio Carlos
Published: January 2023

ABSTRACT BACKGROUND: Complete surgical resection is the main determining factor in the survival of advanced gastric cancer patients, but is not indicated in metastatic disease. The peritoneum is a common site of metastasis and preoperative imaging techniques still fail to detect it. AIM: The aim of this study was to evaluate the role of staging laparoscopy in the staging of advanced gastric cancer patients in a Western tertiary cancer center. METHODS: A total of 130 patients with gastric adenocarcinoma who underwent staging laparoscopy from 2009 to 2020 were evaluated from a prospective database. Clinicopathological characteristics were analyzed to identify factors associated with the presence of peritoneal metastasis and were also evaluated the accuracy and strength of agreement between computed tomography and staging laparoscopy in detecting peritoneal metastasis and the change in treatment strategy after the procedure. RESULTS: The peritoneal metastasis was identified in 66 (50.76%) patients. The sensitivity, specificity, and accuracy of computed tomography in detecting peritoneal metastasis were 51.5, 87.5, and 69.2%, respectively. According to the Kappa coefficient, the concordance between staging laparoscopy and computed tomography was 38.8%. In multivariate analysis, ascites (p=0.001) and suspected peritoneal metastasis on computed tomography (p=0.007) were statistically correlated with peritoneal metastasis. In 40 (30.8%) patients, staging and treatment plans changed after staging laparoscopy (32 patients avoided unnecessary laparotomy, and 8 patients, who were previously considered stage IVb by computed tomography, were referred to surgical treatment). CONCLUSION: The staging laparoscopy demonstrated an important role in the diagnosis of peritoneal metastasis, even with current advances in imaging techniques.
MULTIPLE NEUROENDOCRINE NEOPLASIA IN A PATIENT WITH TYPE I NEUROFIBROMATOSIS (NF1): REPORT OF A NEW MUTATION (NF1, EXONS 2-30 DELETION) AND LITERATURE REVIEW
Authors: KANNO Danilo Toshio , MATTOS Roberta Lais Mendonça de , CAMPOS Fábio Guilherme , SIQUEIRA Rayama Moreira , CARVALHO Rita Barbosa de , REAL MARTINEZ Carlos Augusto
Published: January 2023

ABSTRACT BACKGROUND: Plexiform neurofibromas represent a common neoplasia of type 1 neurofibromatosis in which neurofibromas arise from multiple nerves involving connective tissue and skin and rarely affect the colon and rectum. Co-occurrence of plexiform neurofibromas, neuroendocrine tumors with primary involvement of the rectum, and medullary thyroid carcinoma in patients with neurofibromatosis type 1 is a previously undescribed condition. The aim of this manuscript was to present a case of primary plexiform neurofibroma and neuroendocrine tumors of the upper rectum in a patient with neurofibromatosis type 1 whose genetic sequencing found a novel mutation in the neurofibromatosis type 1 gene and to review the literature. CASE REPORT: A 49-year-old woman with a familial history of neurofibromatosis type 1 complained of abdominal cramps for 6 months. She had previously been submitted for a total thyroidectomy due to medullary thyroid carcinoma. She was submitted to a colonoscopy, which identified a submucosa lesion located in the upper rectum. The patient was referred for a laparoscopic rectosigmoidectomy, and the histopathological study of the surgical specimen identified two different tumors. An immunohistochemical panel was done for histopathological confirmation of the etiology of both lesions. The results of the panel showed intense immunoexpression of S100 protein in the largest and superficial lesion, as well as positivity for chromogranin and synaptophysin in the minor and deep lesion confirming the diagnosis of rectal plexiform neurofibromas concomitant with neuroendocrine tumors. The proliferative activity rate using Ki-67 antibodies showed that both tumors had a low rate of mitotic activity (<1%). Genetic sequence panel identified an undescribed mutation in the neurofibromatosis type 1 gene (deletion, exons 2–30). The patient’s postoperative evolution was uneventful, and she remains well, without recurrence, 3 years after surgery. CONCLUSION: The co-occurrence of medullary thyroid carcinoma, plexiform neurofibromas, and neuroendocrine tumors of the rectum in patients with neurofibromatosis type 1 is an exceptional and undescribed possibility, whose diagnosis can be confirmed by the immunohistochemical staining and genetic panel.
IS -94INS/DELATTG POLYMORPHISM IN THE NUCLEAR FACTOR KAPPA-B1 GENE (NFKB1) ASSOCIATED WITH NECROTIZING ENTEROCOLITIS?
Authors: FERDINANDO Danielle Lopes Teixeira , FRAGA Fernanda Del Campo Braojos , PIATTO Vânia Belintani , SOUZA Antônio Soares
Published: January 2023

ABSTRACT BACKGROUND: Abnormalities in the different stages of the intestinal maturation process cause metabolic and molecular changes. Among the genetic alterations associated with necrotizing enterocolitis, the -94ins/delATTG polymorphism in NFKB1 gene leads to unregulated activation of the NFKB protein due to an increase in the inherent pro-inflammatory state of the premature intestine. AIMS:To determine the prevalence of the -94ins/delATTG polymorphism in NFKB1 gene in neonates with and without necrotizing enterocolitis. METHODS:This is a case-control study, in which 25 neonates were evaluated as the case group and 50 neonates as the control group, of both genders. DNA was extracted from peripheral blood leukocytes, and the site encompassing the polymorphism was amplified by molecular techniques (polymerase chain reaction/polymorphism in restriction fragment length). RESULTS:Necrotizing enterocolitis was diagnosed in 25 (33%) neonates and, of these, 3 (12%) died. Male gender was more prevalent in both groups (p=0.1613): cases (52%) and controls (62%). Moderate and extreme preterm newborns were predominant in both groups: cases (80%) and controls (88%) (p=0.3036). Low birth weight and extremely low birth weight newborns were the most prevalent in cases (78%), and very low birth weight and extremely low birth weight were the most prevalent in controls (81%) (p=0.1073). Clinical treatment was successful in 72%, and hospital discharge was achieved in 88% of newborns with NEC. The -94ins/delATTG polymorphism in NFKB1 gene was not identified in all the 150 alleles analyzed (100%). CONCLUSIONS:The absence of the -94ins/delATTG polymorphism in NFKB1 gene in newborns with and without necrotizing enterocolitis does not rule out the possibility of alterations in this and/or in other genes in newborns with this condition, which reinforces the need for further research.
PANCREATIC SOLID-PSEUDOPAPILLARY NEOPLASM IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS
Authors: MEIRA-JÚNIOR José Donizeti , YOGOLARE Gustavo Gonçalves , MAGALHÃES Daniel de Paiva , NAMUR Guilherme Naccache , CAMPOS Fabio Guilherme , SEGATELLI Vanderlei , NAHAS Sergio Carlos , JUKEMURA Jose
Published: January 2023

ABSTRACT BACKGROUND: Solid pseudopapillary neoplasm of the pancreas is an uncommon pancreatic tumor, which is more frequent in young adult women. Familial adenomatous polyposis is a genetic condition associated with colorectal cancer that also increases the risk of developing other tumors as well. AIM: The aim of this study was to discuss the association of familial adenomatous polyposis with solid pseudopapillary neoplasm of the pancreas, which is very rare. METHODS: We report two cases of patients with familial adenomatous polyposis who developed solid pseudopapillary neoplasm of the pancreas of the pancreas and were submitted to laparoscopic pancreatic resections with splenic preservation (one male and one female). RESULTS: ß-catenin and Wnt signaling pathways have been found to play an important role in the tumorigenesis of solid pseudopapillary neoplasm of the pancreas, and their constitutive activation due to adenomatous polyposis coli gene inactivation in familial adenomatous polyposis may explain the relationship between familial adenomatous polyposis and solid pseudopapillary neoplasm of the pancreas. CONCLUSION: Colonic resection must be prioritized, and a minimally invasive approach is preferred to minimize the risk of developing desmoid tumor. Pancreatic resection usually does not require extensive lymphadenectomy for solid pseudopapillary neoplasm of the pancreas, and splenic preservation is feasible.
Crenças de Professores sobre Violência Sexual contra Crianças e Adolescentes
Authors: Duarte Thaina de Morais , Patias Naiana Dapieve , Hohendorff Jean Von
Published: January 2023

Resumo Objetivou-se investigar as crenças de professores acerca da violência sexual contra crianças e adolescentes. Uma amostra de 164 professores de ensino fundamental e médio, de escolas públicas e privadas, respondeu a um questionário sociodemográfico e a Escala de Crenças sobre Abuso Sexual (ECAS). Análises descritivas, de frequência, testes U de Mann-Whitney e teste de Kruskall-Wallis foram realizados. O escore médio da ECAS, nessa amostra, foi de 25,74 (DP = 6,83), indicando uma tendência à discordância e neutralidade à tolerância/legitimação. Ao se comparar grupos, as variáveis gênero, faixa etária e presença de filhos mostraram ter influência sob as crenças. A experiência com casos de suspeita, participação em cursos ou palestras e conhecimento do Estatuto da Criança e do Adolescente não apresentaram diferenças estatisticamente significativas em relação às crenças. Tais resultados foram discutidos a partir de considerações sobre gênero, sexualidade, capacitação profissional e características de crenças. É necessário investimento em estratégias de formação continuada, sendo que devem ser sensíveis às características dos participantes e às suas crenças.
SOCIAL SKILLS TRAINING IN UNDERGRADUATE STUDENTS: A SYSTEMATIC REVIEW
Authors: Lessa Tatiane Cristina Rodrigues , Prette Almir Del , Prette Zilda Aparecida Pereira Del
Published: January 2023

ABSTRACT Intervention programs based on Social Skills Training have been researched in different populations, including university students. This study aimed to review the literature about HST programs with university students, published in national and international journals, emphasizing the instruments and designs used, in addition to the main results and limitations, from 1980 onwards. The keywords in English “social skills training”, “undergraduate”, “graduate students” and “higher education” were used in six databases (Capes, ERIC, PHS/RIHS, DOAJ, EBSChost, LILACS, IBICT, WEB OF SCIENCE). Thirteen articles were found and they were analyzed regarding the variables of interest by applying the PRISMA Protocol. The results showed that nine studies used the Social Skills Inventory as the main data collection instrument and had an experimental design. The number of sessions was variable among the interventions and, in all studies, there was an improvement in the social skills repertoire of the research participants. This article contributes to the literature in the area by discussing implications for research and practice in promoting social skills in university education, as well as directions for future research that should consider the concept of social competence.
Survival in hemodialysis in Brazil according to the source of payment for the treatment: Public Healthcare System (SUS) versus private insurance
Authors: Barra Ana Beatriz Lesqueves , Silva Ana Paula Roque da , Canziani Maria Eugenia F. , Lugon Jocemir Ronaldo , Matos Jorge Paulo Strogoff de
Published: January 2023

ABSTRACT Introduction: Brazil has the largest public and universal healthcare system in the world, but little is known about the outcomes of patients on hemodialysis (HD) in the country according to the source of funding for the treatment. Objective: To compare the profile and survival of patients under HD treatment funded by the Public Healthcare System (SUS) to those with private insurance. Methods: Retrospective analysis of adults undergoing HD between 2012 and 2017 in 21 dialysis centers in Brazil that provided both by the SUS and private health insurance. Participants, regardless of the paying source, received similar dialysis treatment. Data were censored after 60 months of follow-up or at the end of 2019. Results: 4,945 patients were included, 59.7% of which were financed by the SUS. Patients financed by SUS, compared to those with private insurance, were younger (58 vs. 60 years; p < 0.0001) and with a lower prevalence of diabetes (35.8% vs. 40.9%; p < 0.0001). The 60-month survival rates in these groups were 51.1% and 52.1%, respectively (p = 0.85). In the analysis of the subdistribution proportional hazard ratio by the Fine-Gray model, including adjustment for concurrent outcomes, a significant increase in the risk ratio for death was found (1.22 [95% confidence interval 1.04 to 1.43]) in patients with treatment funded by the SUS. Conclusions: Patients on HD with treatment funded by the SUS have a higher adjusted risk of death when compared to those with private insurance, despite similar dialysis treatment. Factors not directly related to dialysis therapy could explain this difference.
Sobrevida na hemodiálise no Brasil de acordo com a fonte pagadora do tratamento: Sistema Único de Saúde versus convênio privado
Authors: Barra Ana Beatriz Lesqueves , Silva Ana Paula Roque da , Canziani Maria Eugenia F. , Lugon Jocemir Ronaldo , Matos Jorge Paulo Strogoff de
Published: January 2023

Resumo Introdução: O Brasil possui o maior sistema público e universal de saúde do mundo, mas pouco se sabe sobre os desfechos dos pacientes em hemodiálise (HD) no país de acordo com a fonte de financiamento do tratamento. Objetivo: Comparar o perfil e a sobrevida dos pacientes que têm o tratamento de HD custeado pelo Sistema Único de Saúde (SUS) com aqueles com convênio privado. Métodos: Análise retrospectiva dos adultos incidentes em HD entre 2012 e 2017 em 21 centros de diálise no Brasil que atendiam tanto pelo SUS quanto por convênios privados. Os participantes, independentemente da fonte pagadora, receberam tratamento dialítico semelhante. Os dados foram censurados com 60 meses de acompanhamento ou ao final de 2019. Resultados: Foram incluídos 4945 pacientes, sendo 59,7% financiados pelo SUS. Os pacientes financiados pelo SUS, em comparação aos que tinham convênio privado, eram mais jovens (58 vs 60 anos; p < 0,0001) e com menor prevalência de diabetes (35,8% vs 40,9%; p < 0,0001). As taxas de sobrevida, em 60 meses nesses grupos foram de 51,1% e 52,1%, respectivamente (p = 0,85). Na análise da razão de risco proporcional de subdistribuição pelo modelo de Fine-Gray, incluindo ajuste para desfechos concorrentes, foi encontrado um aumento significativo na razão de risco para morte (1,22 [intervalo de confiança de 95% 1,04 a 1,43]) nos pacientes com tratamento custeado pelo SUS. Conclusões: Pacientes em HD com tratamento custeado pelo SUS têm um risco ajustado de morte mais elevado do que aqueles com convênio privado, apesar do tratamento dialítico semelhante. Fatores não relacionados diretamente à terapia dialítica poderiam justificar esta diferença.
Effects of different force directions of intra-oral skeletally anchored maxillary protraction on craniomaxillofacial complex, in Class III malocclusion: a 3D finite element analysis
Authors: GARG Dhiraj , RAI Priyank , TRIPATHI Tulika , KANASE Anup
Published: January 2023

ABSTRACT Introduction: The intra-oral skeletally anchored maxillary protraction (I-SAMP) has been found to be an effective treatment for skeletal Class III malocclusion. Objective: This in-silico study explored the influence of different force directions of intra-oral skeletally anchored Class III elastics on the changes in craniomaxillofacial complex, using finite element analysis. Methods: A 3-dimensional (3D) finite element model of the craniomaxillofacial bones including circummaxillary sutures was constructed with high biological resemblance. A 3D assembly of four miniplates was designed and fixed on the maxilla and mandible of the finite element model. The model was applied with 250g/force at the miniplates at three angulations (10°, 20°, and 30°) from the occlusal plane, to measure stress and displacement by using the ANSYS software. Results: The zygomaticotemporal, zygomaticomaxillary, and sphenozygomatic sutures played significant roles in the forward displacement and counterclockwise rotation of maxilla and zygoma, irrespective of the angulation of load application. The displacements and rotations of the zygomatico-maxillary complex decreased gradually with an increase in the angle of load application between miniplates from 10° to 30°. The mandible showed negligible displacement, with clockwise rotation. Conclusions: The treatment effects of I-SAMP were corroborated, with insight of displacement patterns and sutures involved, which were lacking in the previously conducted 2D and 3D imaging studies. The prescribed angulation of skeletally anchored Class III elastics should be as low as possible, since the displacement of zygomatico-maxillary complex increases with the decrease in angulation of the elastics.
Cartesian three-dimensional method to quantify displacements between cone beam computed tomography models
Authors: CASAGRANDE Caroline Pelagio Maués , CASAGRANDE Marcus Vinicius Sena , TEIXEIRA Andressa Otranto de Brito , ALENCAR David Silveira , DIAS Bruno Santos de Barros , ALMEIDA Rhita Cristina Cunha , QUINTÃO Cátia Abdo , CARVALHO Felipe Assis Ribeiro
Published: January 2023

ABSTRACT Introduction: Research in Orthodontics and Oral Surgery has been relying on three-dimensional (3D) models to evaluate treatment results with displacement color map techniques, even though it has important limitations. Objectives: This study proposed a method of tracking translational movements of 3D objects to evaluate displacements in surfaces with no shape modification. Methods: Cone Beam Computed Tomography (CBCT) data of ten patients were imported to the Dolphin software. A hypothetical virtual surgical plan (randomly defined) was developed in the software and afterwards verified using the proposed method. All the procedures were carried out by two evaluators, in two different time-points, with a 15-day interval. ITK-Snap software was used to generate high quality STL models. Centroid points were automatically generated and their coordinates were compared to confirm if they represented the known displacements simulated. The paired t-test and the Bland-Altman plots were used, as well as the intraclass correlation coefficient. Results: Interexaminers and intra-examiner tests showed excellent reliability of the method, with mean displacement measurement error values under 0.1mm. The paired t-test did not show any statistically significant differences. Conclusion: The method showed excellent reliability to track the simulated translational displacements of bone segments.
Chlorophyceae e Trebouxiophyceae (Chlorophyta) em ambientes lóticos na área de influência da Usina Hidrelétrica do Baixo Iguaçu, Estado do Paraná, Brasil
Authors: Silva Maria Julia Lopes da , Pilatti Maria Clara , Bortolini Jascieli Carla , Baumgartner Gilmar , Bueno Norma Catarina
Published: January 2023

A presença de microalgas das classes Chlorophyceae e Trebouxiophyceae em ambientes lóticos se destaca por sua alta diversidade morfológica e sua capacidade de indicar a qualidade da água. Este trabalho objetivou realizar o levantamento taxonômico em rios da área de influência da Usina Hidrelétrica do Baixo Iguaçu. As amostragens mensais foram realizadas de janeiro de 2019 a dezembro de 2019 possibilitando a identificação de 55 táxons, distribuídos em oito famílias Hydrodictyaceae, Scenedesmaceae, Selenastraceae, Sphaeropleaceae, Volvocaceae, Chlorellaceae, Oocystaceae e Trebouxiophyceae incertae sedis. Dentre os táxons identificados, 12 são novas citações para o Estado do Paraná: Monactinus simplex var. echinulatum (Wittrock) Pérez, Monactinus simplex var. sturmii (Reinsch) Pérez, Pseudopediastrum boryanum var. longicorne (Reinsch) Tsarenko, Desmodesmus lefevrei (Deflandre) S.S.An, T.Friedl & E.H.Hegewald, Desmodesmus opoliensis var. carinatus (Lemmermann) E.Hegewald, Desmodesmus perforatus (Lemmermann) E.Hegewald, Pectinodesmus javanensis (Chodat) E.Hegewald, Scenedesmus acunae Comas Gonzáles, Quadrigula closterioides (Bohlin) Printz, Volvox globator Linnaeus, Actinastrum aciculare f. minimum (Huber-Pestalozzi), Actinastrum hantazschii var. subtile Woloszynska.