bluuebunny/crossref_metadata_2025 huggingface dataset:
Map-Based Indoor Pedestrian Navigation Using an Auxiliary Particle Filter
Authors: Yu Chunyang , El-Sheimy Naser , Lan Haiyu , Liu Zhenbo
Published: July 2017

In this research, a non-infrastructure-based and low-cost indoor navigation method is proposed through the integration of smartphone built-in microelectromechanical systems (MEMS) sensors and indoor map information using an auxiliary particle filter (APF). A cascade structure Kalman particle filter algorithm is designed to reduce the computational burden and improve the estimation speed of the APF by decreasing its update frequency and the number of particles used in this research. In the lower filter (Kalman filter), zero velocity update and non-holonomic constraints are used to correct the error of the inertial navigation-derived solutions. The innovation of the design lies in the combination of upper filter (particle filter) map-matching and map-aiding methods to further constrain the navigation solutions. This proposed navigation method simplifies indoor positioning and makes it accessible to individual and group users, while guaranteeing the system’s accuracy. The availability and accuracy of the proposed algorithm are tested and validated through experiments in various practical scenarios.
Whole Grain Intake and Glycaemic Control in Healthy Subjects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Marventano Stefano , Vetrani Claudia , Vitale Marilena , Godos Justyna , Riccardi Gabriele , Grosso Giuseppe
Published: July 2017

Backgrounds: There is growing evidence from both observational and intervention studies that Whole Grain (WG) cereals exert beneficial effects on human health, especially on the metabolic profile. The aim of this study was to perform a meta-analysis of randomised controlled trials (RCT) to assess the acute and medium/long-term effect of WG foods on glycaemic control and insulin sensitivity in healthy individuals. Methods: A search for all the published RCT on the effect of WG food intake on glycaemic and insulin response was performed up to December 2016. Effect size consisted of mean difference (MD) and 95% CI between the outcomes of intervention and the control groups using the generic inverse-variance random effects model. Results: The meta-analysis of the 14 studies testing the acute effects of WG foods showed significant reductions of the post-prandial values of the glucose iAUC (0–120 min) by −29.71 mmol min/L (95% CI: −43.57, −15.85 mmol min/L), the insulin iAUC (0–120 min) by −2.01 nmol min/L (95% CI: −2.88, −1.14 nmol min/L), and the maximal glucose and insulin response. In 16 medium- and long-term RCTs, effects of WG foods on fasting glucose and insulin and homeostatic model assessment-insulin resistance values were not significant. Conclusions: The consumption of WG foods is able to improve acutely the postprandial glucose and insulin homeostasis compared to similar refined foods in healthy subjects. Further research is needed to better understand the long-term effects and the biological mechanisms.
Self-Reported Non-Celiac Wheat Sensitivity in High School Students: Demographic and Clinical Characteristics
Authors: Carroccio Antonio , Giambalvo Ornella , Blasca Francesco , Iacobucci Rosario , D’Alcamo Alberto , Mansueto Pasquale
Published: July 2017

Background: Non-Celiac Wheat Sensitivity (NCWS) has recently been included among the gluten-related disorders. As no biomarkers of this disease exist, its frequency has been estimated based on self-reported symptoms, but to date no data are available about self-reported NCWS in teenagers. Aim: To explore the prevalence of self-reported NCWS in a group of high school students and to study their demographic and clinical characteristics. Methods: The study was performed between April 2015 and January 2016 in two high schools of a coastal town in the south of Sicily (Italy). A total of 555 students (mean age 17 years, 191 male, 364 female) completed a modified validated questionnaire for self-reported NCWS. The subjects who self-reported NCWS were then compared with all the others. Results: Seven individuals (1.26%) had an established diagnosis of CD. The prevalence of self-reported NCWS was 12.2%, and 2.9% were following a gluten-free diet (GFD). Only 15 out of 68 (23%) NCWS self-reporters had consulted a doctor for this problem and only nine (14%) had undergone serological tests for celiac disease. The NCWS self-reporters very often had IBS symptoms (44%). Conclusions: Self-reported NCWS was found to be common in teenagers, with a frequency of 12.2%; the frequency of GFD use was 2.9%, which was much higher than the percentage of known CD in the same population (1.26%). A greater awareness of the possible implications on the part of the subjects involved, and a more thorough medical approach to the study of self-reported wheat-induced symptoms are required.
Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice
Authors: Cialdella-Kam Lynn , Ghosh Sujoy , Meaney Mary , Knab Amy , Shanely R. , Nieman David
Published: July 2017

Quercetin (Q) and green tea extract (E) are reported to counter insulin resistance and inflammation and favorably alter fat metabolism. We investigated whether a mixture of E + Q (EQ) could synergistically influence metabolic and inflammation endpoints in a high-fat diet (HFD) fed to mice. Male C57BL/6 mice (n = 40) were put on HFD (fat = 60%kcal) for 12 weeks and randomly assigned to Q (25 mg/kg of body weight (BW)/day), E (3 mg of epigallocatechin gallate/kg BW/day), EQ, or control groups for four weeks. At 16 weeks, insulin sensitivity was measured via the glucose tolerance test (GTT), followed by area-under-the-curve (AUC) estimations. Plasma cytokines and quercetin were also measured, along with whole genome transcriptome analysis and real-time polymerase chain reaction (qPCR) on adipose, liver, and skeletal muscle tissues. Univariate analyses were conducted via analysis of variance (ANOVA), and whole-genome expression profiles were examined via gene set enrichment. At 16 weeks, plasma quercetin levels were higher in Q and EQ groups vs. the control and E groups (p < 0.05). Plasma cytokines were similar among groups (p > 0.05). AUC estimations for GTT was 14% lower for Q vs. E (p = 0.0311), but non-significant from control (p = 0.0809). Genes for cholesterol metabolism and immune and inflammatory response were downregulated in Q and EQ groups vs. control in adipose tissue and soleus muscle tissue. These data support an anti-inflammatory role for Q and EQ, a result best captured when measured with tissue gene downregulation in comparison to changes in plasma cytokine levels.
Influences of Orally Taken Carotenoid-Rich Curly Kale Extract on Collagen I/Elastin Index of the Skin
Authors: Meinke Martina , Nowbary Ceylan , Schanzer Sabine , Vollert Henning , Lademann Jürgen , Darvin Maxim
Published: July 2017

Two differently designed, spatially resolved reflectance spectroscopy-based scanners and two-photon tomography were used for noninvasive in vivo determination of cutaneous carotenoids, and collagen I/elastin aging index of dermis, respectively, in the skin of 29 healthy female volunteers between 40 and 56 years of age. The volunteers received a supplement in the form of a carotenoid-rich natural curly kale extract containing 1650 µg of carotenoids in total (three capsules of 550 µg), once a day. Measurements were taken before, after 5 months and after 10 months of daily supplementation. The results showed significantly increased values for the cutaneous carotenoids and the collagen I/elastin aging index of dermis 5 and 10 months after the beginning of the study. The obtained results show that a natural carotenoid-rich extract could prevent the aging-related collagen I degradation in the dermis and improve the extracellular matrix.
Food-Derived Antioxidant Polysaccharides and Their Pharmacological Potential in Neurodegenerative Diseases
Authors: Li Haifeng , Ding Fei , Xiao Lingyun , Shi Ruona , Wang Hongyu , Han Wenjing , Huang Zebo
Published: July 2017

Oxidative stress is known to impair architecture and function of cells, which may lead to various chronic diseases, and therefore therapeutic and nutritional interventions to reduce oxidative damages represent a viable strategy in the amelioration of oxidative stress-related disorders, including neurodegenerative diseases. Over the past decade, a variety of natural polysaccharides from functional and medicinal foods have attracted great interest due to their antioxidant functions such as scavenging free radicals and reducing oxidative damages. Interestingly, these antioxidant polysaccharides are also found to attenuate neuronal damages and alleviate cognitive and motor decline in a range of neurodegenerative models. It has recently been established that the neuroprotective mechanisms of polysaccharides are related to oxidative stress-related pathways, including mitochondrial function, antioxidant defense system and pathogenic protein aggregation. Here, we first summarize the current status of antioxidant function of food-derived polysaccharides and then attempt to appraise their anti-neurodegeneration activities.
The Consumption of Dietary Antioxidant Vitamins Modifies the Risk of Obesity among Korean Men with Short Sleep Duration
Authors: Doo Miae , Kim Yangha
Published: July 2017

Short sleep duration has been reported to be associated with various health problems. This study examined the influence of sleep duration on the odds of being obese in relation to the consumption of dietary antioxidant vitamins among 3941 Korean men between 40 and 69 years of age. After adjusting for age, education, household income, marital status, insomnia, smoking and drinking status, participants with short sleep duration (<6 h) had significantly higher body mass index (p = 0.005), body fat mass (p = 0.010), body fat percentage (p = 0.021), waist circumference (p = 0.029), as well as the odds ratio (OR) of risk of obesity [OR (95% CI) = 1.467 (1.282–1.678)], compared to participants with optimal sleep duration (≥7 h). Short sleepers with a low consumption of dietary antioxidant vitamins had a higher risk of obesity than those with a high consumption of dietary antioxidant vitamins; however, this relationship did not hold among those with optimal sleep duration. Although a causal relationship among sleep-related variables could not be definitively demonstrated because of this study’s cross-sectional design, our results suggested that the increased risk of obesity associated with short sleep duration may be modified by the consumption of dietary antioxidant vitamins.
Ultra High Electrical Performance of Nano Nickel Oxide and Polyaniline Composite Materials
Authors: Cai Xiaomin , Cui Xiuguo , Zu Lei , Zhang You , Gao Xing , Lian Huiqin , Liu Yang , Wang Xiaodong
Published: July 2017

The cooperative effects between the PANI (polyaniline)/nano-NiO (nano nickel oxide) composite electrode material and redox electrolytes (potassium iodide, KI) for supercapacitor applications was firstly discussed in this article, providing a novel method to prepare nano-NiO by using β-cyelodextrin (β-CD) as the template agent. The experimental results revealed that the composite electrode processed a high specific capacitance (2122.75 F·g−1 at 0.1 A·g−1 in 0.05 M KI electrolyte solution), superior energy density (64.05 Wh·kg−1 at 0.2 A·g−1 in the two-electrode system) and excellent cycle performance (86% capacitance retention after 1000 cycles at 1.5 A·g−1). All those ultra-high electrical performances owe to the KI active material in the electrolyte and the PANI coated nano-NiO structure.
Erratum: Wellmer, F.-W.; Scholz, R.W. Putting Phosphorus First: The Need to Know and Right to Know Call for a Revised Hierarchy of Natural Resources. Resources 2017, 6, 20
Authors:   Resources Editorial Office
Published: July 2017

The corresponding author for this article should be Friedrich-W. Wellmer instead of Roland W. Scholz. [...]
Stress Testing German Industry Sectors: Results from a Vine Copula Based Quantile Regression
Authors: Fischer Matthias , Kraus Daniel , Pfeuffer Marius , Czado Claudia
Published: July 2017

Measuring interdependence between probabilities of default (PDs) in different industry sectors of an economy plays a crucial role in financial stress testing. Thereby, regression approaches may be employed to model the impact of stressed industry sectors as covariates on other response sectors. We identify vine copula based quantile regression as an eligible tool for conducting such stress tests as this method has good robustness properties, takes into account potential nonlinearities of conditional quantile functions and ensures that no quantile crossing effects occur. We illustrate its performance by a data set of sector specific PDs for the German economy. Empirical results are provided for a rough and a fine-grained industry sector classification scheme. Amongst others, we confirm that a stressed automobile industry has a severe impact on the German economy as a whole at different quantile levels whereas, e.g., for a stressed financial sector the impact is rather moderate. Moreover, the vine copula based quantile regression approach is benchmarked against both classical linear quantile regression and expectile regression in order to illustrate its methodological effectiveness in the scenarios evaluated.
Expansion of Industrial Plantations Continues to Threaten Malayan Tiger Habitat
Authors: Shevade Varada S. , Potapov Peter V. , Harris Nancy L. , Loboda Tatiana V.
Published: July 2017

Southeast Asia has some of the highest deforestation rates globally, with Malaysia being identified as a deforestation hotspot. The Malayan tiger, a critically endangered subspecies of the tiger endemic to Peninsular Malaysia, is threatened by habitat loss and fragmentation. In this study, we estimate the natural forest loss and conversion to plantations in Peninsular Malaysia and specifically in its tiger habitat between 1988 and 2012 using the Landsat data archive. We estimate a total loss of 1.35 Mha of natural forest area within Peninsular Malaysia over the entire study period, with 0.83 Mha lost within the tiger habitat. Nearly half (48%) of the natural forest loss area represents conversion to tree plantations. The annual area of new plantation establishment from natural forest conversion increased from 20 thousand ha year−1 during 1988–2000 to 34 thousand ha year−1 during 2001–2012. Large-scale industrial plantations, primarily those of oil palm, as well as recently cleared land, constitute 80% of forest converted to plantations since 1988. We conclude that industrial plantation expansion has been a persistent threat to natural forests within the Malayan tiger habitat. Expanding oil palm plantations dominate forest conversions while those for rubber are an emerging threat.
Zinc Oxide-Based Self-Powered Potentiometric Chemical Sensors for Biomolecules and Metal Ions
Authors: Israr-Qadir Muhammad , Jamil-Rana Sadaf , Nur Omer , Willander Magnus
Published: July 2017

Advances in the miniaturization and portability of the chemical sensing devices have always been hindered by the external power supply problem, which has focused new interest in the fabrication of self-powered sensing devices for disease diagnosis and the monitoring of analytes. This review describes the fabrication of ZnO nanomaterial-based sensors synthesized on different conducting substrates for extracellular detection, and the use of a sharp borosilicate glass capillary (diameter, d = 700 nm) to grow ZnO nanostructures for intracellular detection purposes in individual human and frog cells. The electrocatalytic activity and fast electron transfer properties of the ZnO materials provide the necessary energy to operate as well as a quick sensing device output response, where the role of the nanomorphology utilized for the fabrication of the sensor is crucial for the production of the operational energy. Simplicity, design, cost, sensitivity, selectivity and a quick and stable response are the most important features of a reliable sensor for routine applications. The review details the extra- and intra-cellular applications of the biosensors for the detection and monitoring of different metallic ions present in biological matrices, along with the biomolecules glucose and cholesterol.
Multifunctional Water Sensors for pH, ORP, and Conductivity Using Only Microfabricated Platinum Electrodes
Authors: Lin Wen-Chi , Brondum Klaus , Monroe Charles , Burns Mark
Published: July 2017

Monitoring of the pH, oxidation-reduction-potential (ORP), and conductivity of aqueous samples is typically performed using multiple sensors. To minimize the size and cost of these sensors for practical applications, we have investigated the use of a single sensor constructed with only bare platinum electrodes deposited on a glass substrate. The sensor can measure pH from 4 to 10 while simultaneously measuring ORP from 150 to 800 mV. The device can also measure conductivity up to 8000 μS/cm in the range of 10 °C to 50 °C, and all these measurements can be made even if the water samples contain common ions found in residential water. The sensor is inexpensive (i.e., ~$0.10/unit) and has a sensing area below 1 mm2, suggesting that the unit is cost-efficient, robust, and widely applicable, including in microfluidic systems.
Thermal Anemometry Grid Sensor
Authors: Arlit Martin , Schleicher Eckhard , Hampel Uwe
Published: July 2017

A novel thermal anemometry grid sensor was developed for the simultaneous measurement of cross-sectional temperature and axial velocity distribution in a fluid flow. The sensor consists of a set of platinum resistors arranged in a regular grid. Each platinum resistor allows the simultaneous measurement of fluid temperature via electrical resistance and flow velocity via constant voltage thermal anemometry. Cross-sectional measurement was enabled by applying a special multiplexing-excitation scheme. In this paper, we present the design and characterization of a prototypical sensor for measurements in a range of very low velocities.
Sustainable Retailing in the Fashion Industry: A Systematic Literature Review
Authors: Yang Shuai , Song Yiping , Tong Siliang
Published: July 2017

Although sustainability in the fashion industry has gained prominence from both business practices and academic research, retailing, a vital part of the supply chain, has not yet been fairly explored in academia. The interest in this area has increased lately, mainly due to the growing complexity within this dynamic context. Therefore, it is meaningful to conduct a systematic review of the relevant published literature in this field. This study aims to identify the main perspectives of research on sustainable retailing in the fashion industry. The content analysis results indicate that the most prominent areas in the field are sustainable retailing in disposable fashion, fast fashion, slow fashion, green branding and eco-labeling; retailing of secondhand fashion; reverse logistics in fashion retailing; and emerging retailing opportunities in e-commerce. The results from this review also indicate that there is a lack of research on sustainable retailing in the fashion industry in the developing market.
Epidemiology of Rabies in Lesotho: The Importance of Routine Surveillance and Virus Characterization
Authors: Coetzer Andre , Coertse Jessica , Makalo Mabusetsa Joseph , Molomo Marosi , Markotter Wanda , Nel Louis
Published: July 2017

Rabies is widespread throughout Africa and Asia, despite the fact that the control and elimination of this disease has been proven to be feasible. Lesotho, a small landlocked country surrounded by South Africa, has been known to be endemic for rabies since the 1980s but the epidemiology of the disease remains poorly understood due to limited sample submission, constrained diagnostic capabilities, and a lack of molecular epidemiological data. Considering the existing challenges experienced in Lesotho, we aimed to evaluate the direct, rapid immunohistochemical test (DRIT) as an alternative to the direct fluorescent antibody (DFA) test for rabies diagnosis in Lesotho. Towards this aim, extensive training on the implementation and interpretation of the DRIT was hosted in Lesotho in April 2016 before both tests were applied to all samples subjected to routine rabies diagnosis at the Central Veterinary Laboratory (CVL). We found agreement between the DFA and DRIT assays in 90/96 samples (93.75%). The samples that produced inconsistent results (n = 6) were re-tested a further two times with both assays before being subjected to a real-time qPCR to confirm the diagnosis. Additionally, a statistically significant three-fold increase in the average number of samples submitted per month was observed after the DRIT implementation started, following continuous rabies awareness initiatives amongst the animal health professionals in the country over a 12-month period (p = 0.0279). Partial G-L intergenic regions of selected rabies-positive samples (n = 21) were amplified, sequenced, and subjected to phylogenetic analyses. Molecular epidemiological analyses, that included viruses from neighbouring provinces in South Africa, suggested that at least three independent rabies cycles within Lesotho were implicated in instances of cross-border transmission. This study has evaluated alternative methods for diagnosing and improving rabies surveillance in Lesotho, as well as providing new information that would be of importance in the planning of future disease intervention campaigns, not only in Lesotho, but also in neighbouring South Africa.
Long Term Trends and Dynamics of Dissolved Organic Carbon (DOC) in a Subtropical Reservoir Basin
Authors: Chow Ming , Lai Chao-Chen , Kuo Hsiang-Yi , Lin Chih-Hsien , Chen Tzong-Yueh , Shiah Fuh-Kwo
Published: July 2017

This study evaluates the long term trends and seasonal patterns of dissolved organic carbon (DOC) concentration in the Fei-Tsui Reservoir basin in Northern Taiwan during the period of 2000 to 2015. The non-parametric seasonal Mann-Kendall test was conducted to identify the trends of DOC and its potential drivers (e.g., temperature, runoff, atmospheric acid deposition and stream water chemistry). The monthly tributaries and water surface DOC concentrations in Fei-Tsui Reservoir had showed strong temporal and seasonal variability. The sulfate (SO4) concentration had exhibited statistically significant decreasing trend over a period of 16 years. The decreasing trends of anions (SO4 and NO3) and base cations (Ca and Mg) as well as increasing trends of pH and acidification index (ACI) in Fei-Tsui Reservoir and streams indicated recovery from acidification. However, there was no significant annual trend in DOC concentration of Fei-Tsui Reservoir and streams. Significant positive correlation was obtained between DOC and trophic state index of Fei-Tsui Reservoir. The results suggested that DOC concentration at the water surface of Fei-Tsui Reservoir was mainly driven by the re-oligotrophication and temperature effects rather than a decrease in atmospheric sulfur deposition. Stream DOC concentration was largely determined by the temporal variability in temperature and rainfall. We concluded that climatic and hydrological factors are the dominant drivers for stream DOC dynamics in the study.
Short-Term Impacts of Remeandering Restoration Efforts on Fish Community Structure in a Fourth-Order Stream
Authors: Clark Jennifer , Montemarano Justin
Published: July 2017

Channel reconfiguration is a common but debated method used to restore streams, often causing disturbance and producing subsequent negative impacts on biota. Here, we report results from short-term assessment (i.e., one and three years’ post-restoration) of habitat variables (e.g., reach depth, substrate, and canopy cover) and fish community composition and structure (using electrofishing surveys; e.g., proportion of juveniles and tolerant fishes) from a 675 m section of Eagle Creek (Portage County, OH, USA) restored using channel remeandering in August 2013. Mesohabitat analysis was not conducted as part of this study. Sites upstream and downstream of restoration efforts were also monitored. Surveys were completed in 10 separate 50 m stretches: one upstream control site, three new channel sites, two old channel sites, and three downstream sites. Following restoration, fish communities in downstream sites became more similar to new channel sites and diverged from the upstream control site over time, as reflected in increased proportions of juvenile and tolerant fishes. Shifts in fish communities were not explained by habitat variables. Diversity was significantly lower in new channel sites post-restoration than in the upstream control, while downstream sites remained similarly high in diversity compared to the upstream control site over time. Overall, in the short-term, new channel colonizing communities were unable to recover to reflect upstream community composition and structure, and fish communities downstream of restoration were negatively impacted.
Less is more: Independent loss‐of‐function OCIMENE SYNTHASE alleles parallel pollination syndrome diversification in monkeyflowers (Mimulus)
Authors: Peng Foen , Byers Kelsey J. R. P. , Bradshaw Harvey D.
Published: July 2017

PREMISE OF THE STUDY:

Pollinator‐mediated selection on flower phenotypes (e.g., shape, color, scent) is key to understanding the adaptive radiation of angiosperms, many of which have evolved specialized relationships with a particular guild of animal pollinators (e.g., birds, bats, moths, bees). E‐β‐Ocimene, a monoterpene produced by OCIMENE SYNTHASE (OS) in Mimulus lewisii, is a floral scent important in attracting the species’ bumblebee pollinators. The taxa closely related to M. lewisii have evolved several different pollination syndromes, including hummingbird pollination and self pollination (autogamy). We are interested in how floral scent variation contributed to species diversification in this clade.

METHODS:

We analyzed variation in E‐β‐ocimene emission within this Mimulus clade and explored its molecular basis through a combination of DNA sequencing, reverse transcriptase PCR, and enzyme functional analysis in vitro.

KEY RESULTS:

We found that none of the taxa, other than M. lewisii, emitted E‐β‐ocimene from flowers. But the molecular basis underlying loss of E‐β‐ocimene emission is unique in each taxon, including deletion, missense, or frameshift mutations in the OS gene, and potential posttranscriptional downregulation.

CONCLUSIONS:

The molecular evidence suggests that parallel loss‐of‐function in OS is the best explanation for the observed pattern of E‐β‐ocimene emission, likely as the result of natural selection.
A nanocomplex of C60 fullerene with cisplatin: design, characterization and toxicity
Authors: Prylutska Svitlana , Politenkova Svitlana , Afanasieva Kateryna , Korolovych Volodymyr , Bogutska Kateryna , Sivolob Andriy , Skivka Larysa , Evstigneev Maxim , Kostjukov Viktor , Prylutskyy Yuriy , Ritter Uwe
Published: July 2017

The self-organization of C60 fullerene and cisplatin in aqueous solution was investigated using the computer simulation, dynamic light scattering and atomic force microscopy techniques. The results evidence the complexation between the two compounds. The genotoxicity of С60 fullerene, Cis and their complex was evaluated in vitro with the comet assay using human resting lymphocytes and lymphocytes after blast transformation. The cytotoxicity of the mentioned compounds was estimated by Annexin V/PI double staining followed by flow cytometry. The results clearly demonstrate that water-soluble C60 fullerene nanoparticles (0.1 mg/mL) do not induce DNA strand breaks in normal and transformed cells. C60 fullerene in the mixture with Cis does not influence genotoxic Cis activity in vitro, affects the cell-death mode in treated resting human lymphocytes and reduces the fraction of necrotic cells.
A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E
Authors: Reimann Marcel , Sandjo Louis P , Antelo Luis , Thines Eckhard , Siepe Isabella , Opatz Till
Published: July 2017

Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the suggested stereochemistry. The synthesis was based on a new strategy which includes an efficient access to the 15-guanidino-3-hydroxypentadecanoyl (GHPD) side chain from erucamide.
GASP. II. A MUSE View of Extreme Ram-Pressure Stripping along the Line of Sight: Kinematics of the Jellyfish Galaxy JO201
Authors: Bellhouse C. , Jaffé Y. L. , Hau G. K. T. , McGee S. L. , Poggianti B. M. , Moretti A. , Gullieuszik M. , Bettoni D. , Fasano G. , D’Onofrio M. , Fritz J. , Omizzolo A. , Sheen Y.-K. , Vulcani B.
Published: July 2017

This paper presents a spatially resolved kinematic study of the jellyfish galaxy JO201, one of the most spectacular cases of ram-pressure stripping (RPS) in the GAs Stripping Phenomena in galaxies with MUSE (GASP) survey. By studying the environment of JO201, we find that it is moving through the dense intracluster medium of Abell 85 at supersonic speeds along our line of sight, and that it is likely accompanied by a small group of galaxies. Given the density of the intracluster medium and the galaxy’s mass, projected position, and velocity within the cluster, we estimate that JO201 must so far have lost ∼50% of its gas during infall via RPS. The MUSE data indeed reveal a smooth stellar disk accompanied by large projected tails of ionized (

) gas, composed of kinematically cold (velocity dispersion <40 km s−1) star-forming knots and very warm (>100 km s−1) diffuse emission, that extend out to at least

from the galaxy center. The ionized

-emitting gas in the disk rotates with the stars out to ∼6 kpc; but, in the disk outskirts, it becomes increasingly redshifted with respect to the (undisturbed) stellar disk. The observed disturbances are consistent with the presence of gas trailing behind the stellar component resulting from intense face-on RPS along the line of sight. Our kinematic analysis is consistent with the estimated fraction of lost gas and reveals that stripping of the disk happens outside-in, causing shock heating and gas compression in the stripped tails.
Magnetized Converging Flows toward the Hot Core in the Intermediate/High-mass Star-forming Region NGC 6334 V
Authors: Juárez Carmen , Girart Josep M. , Zamora-Avilés Manuel , Tang Ya-Wen , Koch Patrick M. , Liu Hauyu Baobab , Palau Aina , Ballesteros-Paredes Javier , Zhang Qizhou , Qiu Keping
Published: July 2017

We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s−1, converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamic simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.
The Ages of Passive Galaxies in a z = 1.62 Protocluster
Authors: Lee-Brown Donald B. , Rudnick Gregory H. , Momcheva Ivelina G. , Papovich Casey , Lotz Jennifer M. , Tran Kim-Vy H. , Henke Brittany , Willmer Christopher N. A. , Brammer Gabriel B. , Brodwin Mark , Dunlop James , Farrah Duncan
Published: July 2017

We present a study of the relation between galaxy stellar age and mass for 14 members of the z = 1.62 protocluster IRC 0218, using multiband imaging and HST G102 and G141 grism spectroscopy. Using UVJ colors to separate galaxies into star-forming and quiescent populations, we find that, at stellar masses

, the quiescent fraction in the protocluster is

, consistent with a ∼ 2× enhancement relative to the field value,

. At masses

, f

Q
in the cluster is

, consistent with the field value of

. Using galaxy

values derived from the G102 spectroscopy, we find no relation between galaxy stellar age and mass. These results may reflect the impact of merger-driven mass redistribution—which is plausible, as this cluster is known to host many dry mergers. Alternately, they may imply that the trend in f

Q
in IRC 0218 was imprinted over a short timescale in the protocluster’s assembly history. Comparing our results with those of other high-redshift studies and studies of clusters at

, we determine that our observed relation between f

Q
and stellar mass only mildly evolves between

and

, and only at stellar masses

. Both the

and

results are in agreement that the red sequence in dense environments was already populated at high redshift,

, placing constraints on the mechanism(s) responsible for quenching in dense environments at

.
New Equations of State for Postmerger Supramassive Quark Stars
Authors: Li Ang , Zhu Zhen-Yu , Zhou Xia
Published: July 2017

Binary neutron star (NS) mergers with their subsequent fast-rotating supramassive magnetars are one attractive interpretation for at least some short gamma-ray bursts (SGRBs), based on the internal plateau commonly observed in the early X-ray afterglow. The rapid decay phase in this scenario signifies the epoch when the star collapses to a black hole after it spins down, and could effectively shed light on the underlying unclear equation of state (EoS) of dense matter. In the present work, we compare the protomagnetar masses of the internal plateau sample from representative EoS models to that derived independently from the observed galactic NS–NS binary, aiming to contribute new compact star EoSs from SGRB observations. For this purpose, we employ various EoSs covering a wide range of maximum masses for both NSs and quark stars (QSs) and, at the same time, satisfying the recent observational constraints of the two massive pulsars for which the masses are precisely measured (around

). We first illustrate that how well the underlying EoS would reconcile with the current posterior mass distribution is largely determined by the static maximum mass of that EoS. We then construct three new postmerger QS EoSs (PMQS1, PMQS2, PMQS3), fully respecting the observed distribution. We also provide easy-to-use parameterizations for both the EoSs and the corresponding maximum gravitational masses of rotating stars. In addition, we calculate the fractions of postmerger products for each EoS, and discuss potential consequences for the magnetar-powered kilonova model.
Luminous and Variable Stars in M31 and M33. V. The Upper HR Diagram
Authors: Humphreys Roberta M. , Davidson Kris , Hahn David , Martin John C. , Weis Kerstin
Published: July 2017

We present HR diagrams for the massive star populations in M31 and M33, including several different types of emission-line stars: the confirmed luminous blue variables (LBVs), candidate LBVs, B[e] supergiants, and the warm hypergiants. We estimate their apparent temperatures and luminosities for comparison with their respective massive star populations and evaluate the possible relationships of these different classes of evolved, massive stars, and their evolutionary state. Several of the LBV candidates lie near the LBV/S Dor instability strip that supports their classification. Most of the B[e] supergiants, however, are less luminous than the LBVs. Many are very dusty with the infrared flux contributing one-third or more to their total flux. They are also relatively isolated from other luminous OB stars. Overall, their spatial distribution suggests a more evolved state. Some may be post-RSGs (red supergiants) like the warm hypergiants, and there may be more than one path to becoming a B[e] star. There are sufficient differences in the spectra, luminosities, spatial distribution, and the presence or lack of dust between the LBVs and B[e] supergiants to conclude that one group does not evolve into the other.
Monnaies d’or du xvi e s. découvertes lors d’un diagnostic archéologique à Saint-Georges-sur-l’Aa (Nord)
Authors: Notte Ludovic , Demarly-Cresp Florence
Published: July 2017

Un ensemble de cinq monnaies d’or (trois double ducats espagnols immobilisés aux noms de Ferdinand et d’Isabelle, un réal gueldrois de Charles Quint et un double ducat millésimé 1574 de Jean-Jacques Khuen de Belasi, archevêque de Salzburg) a été découvert lors d’un diagnostic archéologique sur la commune de Saint-Georges-sur-l’Aa (département du Nord). Repéré au décapage sous la semelle des labours, aucune structure, aucun contenant n’a pu lui être associé ; les sources anciennes permettent d’ailleurs de confirmer l’absence de construction dans la parcelle concernée (fief du Bogartland) et de supposer le dépôt dans une pâture. La date exacte (dernier quart du xvi e s. probablement), le responsable et les motivations du dépôt ne peuvent être précisés sauf à insister sur le contexte troublé de l’époque. Un premier essai catalogue des monnaies et dépôts de monnaies d’or découverts dans le Nord de la France est donné en annexe.
Maître François Gibault : réflexions sur une expérience des procès politiques depuis 1962
Authors: Salas Denis
Published: July 2017

le 5 décembre 2016 Maître François Gibault exerce la profession d’avocat depuis soixante ans. Il s’est progressivement spécialisé dans les procès dits « politiques » qu’il a commencé à suivre dès 1962 et qui se sont poursuivis avec les attentats de l’OAS en Algérie, celui du Petit-Clamart en France, jusqu’à l’affaire Bomberski en 2012. De cette longue expérience, il dégage certaines spécificités de la défense : gagner du temps, contester la légalité des procédures et du tribunal.
La cour d’appel de Douai dans la tourmente de la Grande Guerre : « Une seule arme, le droit »
Authors: Humbert Sylvie
Published: July 2017

Comment fonctionne la justice en temps de guerre ? C’est le thème du discours prononcé lors de l’audience solennelle de rentrée de la cour d’appel de Douai le 2 octobre 1919. Douai, « ressort martyr » , est montré en exemple pour « sa foi commune dans la victoire sur la barbarie ». Durant les quatre années d’occupation, la justice ordinaire devait continuer à être rendue. Magistrats, avocats, greffiers, policiers… tous ont pris des risques pour maintenir la vie judiciaire dans le ressort de la cour d’appel de Douai, même au plus fort des combats, malgré les brimades des Allemands, au prix du sacrifice de certains, au ralenti, dans un élan de solidarité nationale, dans le respect du service public, dans un souci d’indépendance, au nom du primat du droit… jusqu’à la Libération.
The Value of Diagnostic Work-Up in the Evaluation of White Dot Syndromes
Authors: Palejwala Neal V. , Sawhney Gagan , Raecker Matthew , Flaxel Chrstina J. , Yeh Steven
Published: July 2017

BACKGROUND AND OBJECTIVE:

To determine the diagnostic yield of systemic work-up in white dot syndromes.

PATIENTS AND METHODS:

A retrospective chart review.

RESULTS:

Eighty-six consecutive patients with a diagnosis of a white dot syndrome were identified. Forty-three had a diagnosis of birdshot chorioretinopathy. Overall, 395 diagnostic tests were performed with a diagnostic yield of 11.9%. The test with the greatest diagnostic yield was HLA-A29 typing (89%). Four patients had abnormal angiotensin converting enzyme levels. No patients had a positive rapid plasma reagin or fluorescent treponemal antibody absorption test. Four patients had positive tuberculosis testing and required treatment. The mean number of tests performed per diagnosis group ranged from 0.3 in multiple evanescent white dot syndrome to 5.6 in multifocal choroiditis and panuveitis. Diagnostic testing was found to be the most expensive in birdshot chorioretinopathy, with a mean cost of $504.82.

CONCLUSIONS:

Diagnostic yield of systemic work-up was low in this patient population. Rather than performing an exhaustive work-up, the authors advocate for a limited work-up tailored to pretest clinical suspicion.

[
Ophthalmic Surg Lasers Imaging Retina
. 2017;48:540–545.]
Choroidal Neovascularization and Geographic Atrophy are Potential Complications of Early Onset Large Colloid Drusen
Authors: Carnevali Adriano , Querques Giuseppe
Published: July 2017

The authors report a case of large colloid drusen (LCD) complicated by choroidal neovascularization (CNV) and geographic atrophy (GA). A 54-year-old man was referred to the authors' department with diagnosis of early onset retinal drusen. Multimodal imaging led to a diagnosis of LCD complicated by GA in the right eye and CNV in the left eye. The patient received a single injection of intravitreal aflibercept (Eylea; Regeneron, Tarrytown, NY) in the left eye. Six months later, best-corrected visual acuity improved to 20/25, and spectral-domain optical coherence tomography still showed absence of subretinal and intraretinal fluid. GA and CNV are possible complications of LCD, and contrary to previous beliefs, it should therefore not be considered as a benign condition. Intravitreal aflibercept could be considered as a useful treatment in cases complicated by CNV.

[

Ophthalmic Surg Lasers Imaging Retina.
2017;48:586–590.

]
In Vivo Microvascular Pattern of Solitary Juxtapapillary Capillary Hemangioma on OCT Angiography
Authors: Thirumalesh M. B. , Jain Astha , Agrawal Sumeet , Bhujang Shetty K.
Published: July 2017

Juxtapapillary capillary hemangioma (JCH) is a vascular hamartoma. Fluorescein fundus angiography aids in diagnosis. The vascular morphology of this tumor has not been documented with optical coherence tomography angiography (OCTA), a new, noninvasive diagnostic modality that provides high-resolution images of vascular pattern based on blood flow in the retina and choroid. Although mainly a clinical diagnosis, OCTA helps in studying the intrinsic vascularity of the tumor and helps in differentiating it from other vascular tumors. The authors report the case of a young male with unilateral solitary JCH and its microvascular pattern, as seen on OCTA.

[

Ophthalmic Surg Lasers Imaging Retina.
2017;48:592–595.

]
Analyzing Interval Systems of Human T-Cell Lymphotropic Virus Type I Infection of CD4+ T-Cells
Authors: Dadi Zohreh
Published: July 2017

Human T-cell lymphotropic virus type I (HTLV-I) infects a type of white blood cell called a T lymphocyte. HTLV-I infection is seen in diverse region of the world such as the Caribbean Islands, southwestern Japan, southeastern United States, and Mashhad (Iran). This virus is the etiological agent of two main types of disease: HTLV-I-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia. Also, the role of HTLV-I in the pathogenesis of autoimmune diseases such as HTLV-I associated arthropathy and systemic lupus erythematosus is under investigation. In this chapter, the author considers an ODE model of T-cell dynamics in HTLV-I infection which was proposed by Stilianakis and Seydel in 1999. Mathematical analysis of the model with fixed parameters has been done by many researchers. The author studies dynamical behavior (local stability) of this model with interval uncertainties, called interval system. Also, effective parameters in the local dynamics of model are found. For this study, interval analysis and particularly of Kharitonov's stability theorem are used.
Global Dynamics of an Immunosuppressive Infection Model Based on a Geometric Approach
Authors: Dadi Zohreh
Published: July 2017

By clinical data, drug treatment sometimes is ineffective to eradicate the infection completely from the host in some human pathogens such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and human T cell lymphotropic virus type I. Therefore, mathematical modeling can play a significant role to understand the interactions between viral replication and immune response. In this chapter, the author investigates the global dynamics of antiviral immune response in an immunosuppressive infection model which was studied by Dadi and Alizade (2016). In this model, the global asymptotic stability of an immune control equilibrium point is proved by using the Poincare–Bendixson property, Volterra–Lyapunov stable matrices, properties of monotone dynamical systems and geometric approach. The analysis and results which are presented in this chapter make building blocks towards a comprehensive study and deeper understanding of the dynamics of immunosuppressive infection model.
Strategic Analytics to Drive Provincial Dialysis Capacity Planning
Authors: Kaw Neal , Sadat Somayeh , Esensoy Ali Vahit , Liu Zhihui (Amy) , Bastedo Sarah Jane , Nesrallah Gihad
Published: July 2017

This chapter discusses applications of analytics at the strategic level of health system planning in the province of Ontario, Canada. To supplement the strategic priorities of the Ontario Renal Plan I, a roadmap developed by the Ontario Renal Network to guide its directions in coordinating renal care province-wide, an interactive user-friendly analytical capacity planning model was developed to forecast the growth of the prevalent chronic dialysis patient population and estimate consequent future need for hemodialysis stations at Ontario's dialysis facilities. The model also projects operational funding to care for dialysis patients, vascular surgeries to achieve arteriovenous fistula targets, peritoneal dialysis catheter insertions to achieve peritoneal dialysis prevalence targets, and incident dialysis patients to be sent home to achieve prevalent home dialysis targets. The model uses a variety of analytical methods, including time series analysis, mathematical optimization, geo-spatial analysis and Monte Carlo simulation.
Non-Parametric Statistical Analysis of Rare Events in Healthcare
Authors: Nasiri Soheila , Raahemi Bijan
Published: July 2017

The assumption of Gaussian distribution of population does not always hold strongly in health studies. The sample size may not be large enough due to the limited nature of observations such as biopsies taken during kidney transplantation, the distribution of sample may not be Gaussian, or the observation may not even be possible for the far ends of a Gaussian distribution. In such cases, an alternative approach, called nonparametric tests can be applied. In this study, a non-parametric single center retrospective analysis of adult kidney transplant is performed to compare histological outcomes among three different groups of deceased kidney donors, based on the biopsies taken before and after kidney transplant at months 1, 3, and 12. A total of 107 transplants were observed in this study with 310 surveillance biopsy taken then classified based on the Banff 97 adequacy assessment. It is concluded that the recipient's internal condition after kidney transplant is as important as the donor's risk factors.