bluuebunny/crossref_metadata_2025 huggingface dataset:
Single and Ternary Removal of Heavy Metals from Aqueous Solution Using Fe3O4 Magnetic Nano-particles
Authors:   Huson University College, Al-Balqa Applied University,, Al-Zboon Kamel K.
Published: March 2023

This research aims to investigate the use of magnetic iron nano-particles (FeN) for the removal of heavy metals under single and ternary scenarios. The methodology includes synthesis of FeN using chemical precipitation approach, batch experiments for single and ternary metals removal, isotherm and kinetic studies, thermos-dynamic study and assessing the effect of different parameters on the adsorption process. The results showed that the maximum removal for As and Hg was achieved at a pH of 7, while a pH of 6 provided a slightly higher removal of Cd than a pH of 7 at an optimum mixing time of 120 minutes. The optimum adsorption capacities of As, Cd and Hg at the initial concentration of 200 ppm were 260, 280 and 75.0 mg/g in the case of single metal removal against 91.5, 237.8 and 341.5 mg/g in the case of ternary combination, respectively. The removal of all metals increased with increasing the FeN dose and the mixing time, while it decreased with the increase of the initial concentration. The removal efficiency was affected strongly by the presence of multiple metals, while As removal decreased sharply and Hg removal increased significantly. Adsorption selectivity is affected negatively by the increase in atomic weight and atomic radius. In the case of single-metal removal, fitting of isotherm models can be ranked as Langmuir>Freundlich>Temkin>D-R for As and Cd and Temkin>Freundlich>D-R>Langmuir for Hg, while contradictory results were obtained in the case of ternary combination. Kinetic studies found that the adsorption follows the pseudo-second-order model with R2=0.99. For all metals, the adsorption process is highly favourable at higher temperatures and is endothermic in nature with (ΔHo) of 10.91, 23.86 and 0.163 for As, Cd and Hg, respectively. Coating of FeN with silica resulted in lower removal efficiency for all metals up to 50%. It can be concluded that FeN can be successfully used for the removal of heavy metals either through the single or ternary approach, but the single approach provides a higher performance. KEYWORDS: Nano-materials, Magnetite iron, Adsorption, Arsenic, Cadmium, Mercury, Lead.
Fabrication of Polystyrene Sulfonate-Chitosan (PSS-Chitosan) Membrane as Dodecyl Benzene Sulfonate (DBS) Adsorbent in Laundry Wastewater
Authors: Nora Mandrea , Bhagaskara Adyatma , Agustisari Virna , Lim Alice , Alfalah Hardian Ridho , Siswanta Dwi
Published: March 2023

The combination of polystyrene and chitosan can form polyelectrolyte (PE) membranes. Polystyrene sulfonate-chitosan (PSS-chitosan) adsorbent membrane can adsorb dodecyl benzene sulfonate (DBS) in laundry wastewater. This study aimed to synthesize, identify characteristics, and formulate adsorption effectiveness by PSS-chitosan membranes. The research methods included converting polystyrene into PSS, isolating chitosan, optimizing geometry, making PSS-chitosan membranes, studying adsorption, and applying membranes to laundry wastewater. The resulting membrane was characterized using FTIR and SEM. The results of the infrared spectra showed vibrations of –OH and –NH2 groups at 3418 cm–1, while the SEM image showed a homogeneous membrane surface. The quality of chitosan isolation from shrimp shells was indicated by the degree of deacetylation of 61.3%. The results of the geometry optimization showed the change in the structure’s total energy after adsorption. The PSS-chitosan membrane is resistant to acids but decomposes under alkaline conditions. Optimum adsorption of PSS-chitosan membrane on DBS occurred at pH 8 for 100 minutes. The adsorption kinetics of the PSS-chitosan membrane follows the first pseudo-order equation. PSS-chitosan membrane adsorption isotherm follows the Langmuir isotherm model with an adsorption capacity and efficiency of 3.97 mg.g–1 and 76.6%, respectively, at 0.6 ppm. At the application stage, the PSS-chitosan membrane could adsorb DBS in laundry wastewater by (62.4 ± 7.2) %.
Metaverse: Deconstruction and Differentiation of Identity Under the New Media Environment
Authors: Mao Xuhui , Li Xuan , Lu Wenli , Li Yazheng
Published: March 2023

The meta-universe is a new media scene based on VR and other technologies. Whether it will cause greater estrangement between people or even social disintegration or high-latitude healing in the future, the key lies in understanding the inner path of people's spiritual communication. From the perspective of the critical school, based on identity, this paper systematically analyzes and demonstrates the performance, causes, and risks of the deconstruction of identity by new media scenarios through a questionnaire survey on the correlation between virtual identity and real identity and adopts the interview method, to explore the social management of the metauniverse under the perspective of identity. By revealing the interaction between the virtual symbolic identity and the real identity, the paper seeks the value compliance of shaping a positive international image of the world with the help of the meta-universe. The research finds that: the hyperreal experience allows users to create and identify with a new self, the role deviation brought by the utopian world affects identity, the privacy leakage in the real world depends on the degree of identity, and the metauniverse challenges the national discourse system.
Efficiency of CFRP torsional strengthening technique for L-shaped spandrel reinforced concrete beams
Authors: Ayaad Noor , Oukaili Nazar
Published: March 2023

The present study aims to get experimentally a deeper understanding of the efficiency of carbon fiber-reinforced polymer (CFRP) sheets applied to improve the torsional behavior of L-shaped reinforced concrete spandrel beams in which their ledges were loaded in two stages under monotonic loading. An experimental program was conducted on spandrel beams considering different key parameters including the cross-sectional aspect ratio (i.e., web height/web thickness), and the availability of the CFRP strengthening system. The ledge of the spandrel beams was exposed during testing to a very high eccentric load, which was transferred to the web of the spandrel beam causing high shear, torsion, and bending moments. Consequently, the applied load resulted in in-plane and out-of-plane deformations of the web accompanied by flexural and shear cracks. This article demonstrates the advantage of using CFRP sheets to strengthen the mentioned members. The applied CFRP sheets increased the failure torsional load by about 37% compared to the identical L-spandrels without strengthening. The outcomes indicate that using CFRP sheets show improvement in restricting the deflections and rotation of L-spandrels due to increasing spandrel stiffness. The reduction in the degree of rotation attained more than 33% in comparison to the spandrel beams without strengthening. The experimental program confirmed the applicability of the proposed strengthening technique for compacted and slender L-shaped spandrel-reinforced concrete beams.
Medyadaki yansımaları ile şehir hastaneleri: İki ulusal gazetenin incelenmesi
Authors: DÖKME YAĞAR Sema , YAĞAR Fedayi
Published: March 2023

Sağlık alanında günümüzün önemli tartışmalı konularından birisi şehir hastaneleridir. Bu çalışma ile birlikte şehir hastaneleri ile ilgili medyada yer alan haberler incelenmiştir. Araştırma kapsamını Milliyet ve Hürriyet Gazetelerinde yer alan 1358 haber oluşturmuştur. Web madenciliği (verilerin elde edilmesi) ve metin madenciliği teknikleri (verilerin analiz edilmesi) kullanılmıştır. Kelime bulutları ile anahtar kelimeler belirlenmiş ve görselleştirme yapılmıştır. Haberlerin negatif, nötr ya da pozitif yönlü olup olmadığını belirlemek için de duygu analizi kullanılmıştır. Hem başlık hem de içeriğe bakıldığında, “Şehir”, “Hastane”, “Sağlık” ve “Hayat” gibi kelimeler dışında en çok dikkat çeken kelimeler “Cumhurbaşkanı”, “Erdoğan” ve “Bakan” olmuştur. Aynı şekilde hem başlık hem de içeriklere bakıldığında çoğunluklu pozitif bir yaklaşımın benimsendiği tespit edilmiştir. Bunların dışında, şehir hastaneleri ile ilgili yapılan haberlerin sayısında son yıllarda önemli artışlar yaşandığı görülmüştür. Sonuç olarak, bireylerin düşüncelerinin ve davranışlarının şekillenmesinde haberler önemli bir rol oynamaktadır. Bu doğrultuda şehir hastaneleri ile ilgili elde ettiğimiz bu çıktıların genel çerçeveyi gösterme noktasında literatüre önemli bir katkı sağlayacağı düşünülmektedir.
Color adjustment of black locust (Robinia pseudoacacia L.) wood by producing chromogenic structure under heat treatment
Authors: Liu Yang , Liu Fu , Chen Yao , Gao Jianmin
Published: March 2023

To improve the appearance of the black locust wood under heat treatment, ammonia (AM), acetic acid (AA), and ammonium acetate (AMA) were adsorbed into the black locust wood flour, with or without aluminum sulfate octadecahydrate (ASO). The color parameters (CIE L*a*b*) of the black locust wood flour treated with different conditions were measured. Diffuse reflectance ultraviolet-visible spectroscopy (DRUV-Vis) and the attenuated total reflection/Fourier transform infrared spectroscopy (ATR-FTIR) were conducted to reveal the changes of the chromophore systems. X-ray photoelectron spectroscopy (XPS) was used to demonstrate the extreme valence of the atomic content and the occurrence of a coordination reaction. The color of the wood flour became reddish after the treatment with AMA+ASO. There was an increase in carbonyl structure and carboxyl structure of the wood flour treated with AMA and ASO.
Surface design of wood-based board to imitate wood texture using 3D printing technology
Authors: Feng Xinhao , Wu Zhihui , Sang Ruijuan , Wang Fei , Zhu Yayuan , Wu Meijin
Published: March 2023

Wood texture has a beautiful appearance and tactile feeling, making it very appropriate for furniture applications. However, the fabrication of a wood texture on wood-based boards can be inefficient and less green when performed using conventional methods. In this study, a wood-like surface on a wood-based board was designed to imitate a wood texture using 3D printing technology. To obtain a high-quality wood texture template for 3D printing, the sharpness of the wood texture was evaluated by image sharpness models, and the scanned wood texture was optimized by colorimetric parameter and sharpness adjustments. The wood texture coating, which was mainly composed of acrylated oligomers, was UV-inkjet 3D printed on the medium-density fiberboard (MDF) from an obtained template. The properties of the printed wood texture coating on the MDF, including its gloss, wearability, adhesion, and hardness, were measured. The results showed that a wood texture coating with high processability can be feasibly 3D printed on MDF to obtain comparable decoration using commercial products.
A comparative study of the structures, crystallinities, Miller indices, crystal parameters, and particle sizes of microwave- and saline water-treated cassava starch
Authors: Sangian Hanny F. , Aruan Irfan , Tamuntuan Gerald H. , Bobanto Maria D. , Sadjab Bayu Achil , Purwadi Ronny , Zulnazri Zulnazri , Masinambow Vecky A. J. , Gunawan Setiyo
Published: March 2023

The structures, crystallinities, Miller indices, and particle sizes of cassava treated with microwave radiation or saline water were analysed and compared. Cassava was milled to sizes of 100 to 120 mesh and then dried under solar radiation for several days. The first set of substrates was treated by microwave radiation at 300 W for 10, 20, or 30 min or at 1000 W for 8 min. The second set of substrates was immersed in saline water for 5 days at salt concentrations of 3.43% or 10% (w/w). The treated substrates were characterised by x-ray diffraction, Fourier transform infra-red spectroscopy, and scanning electron microscopy, and the results were compared with the characteristics of the native substrate. There were significant differences in the characteristics of the microwave- and saline water-treated cassava. Crystallinities of the microwave-treated substrates were lower than those of the saline water-treated samples. A large shift (change in 2θ) in the diffraction peaks was observed for the treated substrates as compared with the native substrate. Examination of the surface morphology suggested that saline water enabled the dissolution and elimination of the undesirable fibres in the substrate; this was not observed for the microwave-treated substrate.
Properties of laminated wood bonded with modified gutta-percha adhesive at various surface roughness profile of laminae
Authors: Karliati Tati , Febrianto Fauzi , Syafii Wasrin , Wahyudi Imam , Sumardi Ihak , Lee Seung Hwan , Kim Nam Hun
Published: March 2023

The properties of laminated wood prepared from sengon wood (Falcataria moluccana Miq. Barneby & Grimes) bonded with a modified gutta-percha (MGP) adhesive at various laminae surface roughness profiles were investigated. The wood laminae were sanded using sand papers of KAG grit designation of 80, 100, 150, 220, 300, and 400. A lower value of KAG grit designation with a lager particle size of sand resulted in a rougher surface of the bonded laminae; a rougher laminae surface profile resulted in a greater shear strength of the laminated wood. The shear strength was highest for laminated wood treated with sand paper of KAG 80 and smallest for laminated wood treated with KAG 400. In general, the bonding strength was enhanced with decreasing KAG grit designation. The adhesion performance, in terms of spread and adhesive penetration, improved after sanding, which widened the contact area on the wood surface.
The effects of crumb rubber on the properties and microstructure of modified starch degradable composites
Authors: Yang Xingxing , He Chunxia , Li Xiaobo , Wang Lei , Yu An
Published: March 2023

Modified starch (MS) degraded composites were prepared via a molding method with starch as a substrate and a blending process with crumb rubber (CR) and added plasticizers such as glycerol, urea, and formamide. The mechanical properties and water absorbability of the MS degraded composites were measured. The functional group variations were confirmed by Fourier transform infrared spectroscopy (FT-IR), and the changes of the functional groups were investigated with a stereoscopic microscope to analyze the microstructure of the composites. The results indicated that the addition of CR substantially improved the performances of degradable composites. When the CR content was 50 wt% of the MS, the interfacial properties of the reinforced materials and the dispersing degree of the filler were improved. Compared with the composite without additive, the tensile strength and bending strength of the composites were increased by 107% and 49.5%, respectively. The minimum water absorption ratio was reduced by 78% compared with the composite without the additive.
Physicochemical characteristics of sago starch-chitosan nanofillers film
Authors: Fauzi Basirah , Mohd Nawawi Mohd Ghazali , Fauzi Roslinda , Mamauod Siti Nur Liyana
Published: March 2023

Starch has potential to be used in new, functional food packaging materials. The attractive factors of starch as a packaging material are its low price and degradable properties. However, brittleness hinders its function as a packaging film. In this study, chitosan nanofillers (CSN) were incorporated into sago starch (SS) formulations to improve the mechanical, physical, and chemical properties of the film. The synthesis of a new formulation from the optimization process resulted in increased mechanical properties; the tensile strength obtained for the sago starch/chitosan nanofillers (SS/CSN) film was 88 MPa compared with 46 MPa for the sago starch film (SSF). In terms of thermogravimetric analysis, the SS/CSN film sustained up to 390 °C with 60% weight loss, whereas SSF experienced a weight loss of 67% at 375 °C. The analyses summarize the concept of using biocomposites to improve the properties of film for the potential purpose in biodegradable packaging plastics.
Wettability effect of the surface morphologies of Musa acuminata leaves
Authors: Abu Hassan Hasrawati , Ghazali Mariyam Jameelah , Meric Cevdet , Azhari Che Husna
Published: March 2023

The biomimetic application was studied for banana leaves (Musa acuminata Colla), which have been commonly used as a traditional cleaning technique for ironing plates. In this study, banana leaf surfaces were subjected to horizontal sliding forces of 5 N, 10 N, 15 N, and 30 N, using a heated plate at 100 °C, 200 °C, 300 °C, and 500 °C. The self-cleaning behavior of the banana leaves was determined by measuring the adhesion force, roughness, and contact angle, which were subsequently correlated with the surface morphology. Based on the results of this study, the adhesion force decreased from 6.39 nN ± 0.42 nN at 100 °C to 0.50 nN ± 0.50 nN at 500 °C with a load of 30 N, whereas the roughness increased from 0.79 µm ± 0.21 µm at 100 °C to 1.12 µm ± 0.30 µm at 500 °C. Furthermore, the contact angle decreased from 124.8° at 100 °C to 104.0° at 500 °C with a load of 30 N. This study established that the morphology of the banana leaves was altered with the temperature during sliding, which correlated with the surface characteristics.
Geometric influence on the net magnetic moment in LaCoO3 thin films
Authors: Joshi T. , Belanger D. P. , Tan Y. T. , Wen W. , Lederman D.
Published: March 2023

The different magnetic behaviors of LaCoO$$_3$$

3

films grown on LaAlO$$_3$$

3

and SrTiO$$_3$$

3

substrates are related to the Co–O–Co bond angles and the constraints imposed on the Co–O bond lengths by the substrate geometries. The observed magnetic behavior is not consistent with ferromagnetism. Rather, long-range antiferromagnetic order occurs below $$T \approx 90$$

T
≈
90

 K when the Co–O–Co bond angle is greater than 163$$^\circ$$

∘

, consistent with the behavior of bulk and nanoparticles forms of LaCoO$$_3$$

3

. A LaAlO$$_3$$

3

substrate prevents magnetic long-range order at low temperatures near the film–substrate interface and collinear antiferromagnetic sublattices away from the interface. At low temperatures, the antiferromagnetically ordered sublattices are non-collinear in films grown on SrTiO$$_3$$

3

substrates, leading to a significant net moment. The net moment is controlled by the geometry imposed by the substrate upon which the LaCO$$_3$$

3

film is grown.

Graphical abstract
Solid solubility in the CeTi2O6–CeTiNbO6 system: A multi-element X-ray spectroscopic study
Authors: Dixon Wilkins M. C. , Stennett M. C. , McCloy J. S. , Corkhill C. L.
Published: March 2023

In order to investigate the limits of solid solubility between Ce-brannerite (CeTi2O6) and Ce-aeschynite (CeTiNbO6), materials in the system CeTi2–xNbxO6 have been produced by a solid state route and characterised by XRD and XANES at the Ce L3-, Ti K- and Nb K-edges, including Rietveld method refinements and linear combination fitting. Significant solid solubility was observed at the brannerite end, with near-single-phase brannerite observed for x = 0.2, 0.4, and only minor aeschynite observed where x = 0.6 which was identified as exceeding the limit of solubility of Nb. All Nb was present as Nb5+, with the substitution of Nb5+ into the brannerite structure permitted by the reduction of the same fraction of Ce4+ to Ce3+. This work expands the crystal chemistry of the titanate brannerites, with Ce-site oxidation states of less than 4+ being possible where sufficient charge-balancing species are available on the Ti-site.

Graphical abstract
Annual All-Russian conference "New Year’s meetings at Petroverigsky". Collection of abstracts
Authors: Editorial Article
Published: March 2023

.
Use of brick dust to optimise the dewatering process of hydrated lime mortars for conservation applications
Authors: Su-Cadirci Tugce Busra , Ince Ceren , Calabria-Holley Juliana , Ball Richard J.
Published: March 2023

The impact of dewatering on lime mortars modified using brick dust was studied, as it is of particular importance in conservation applications. Dewatering takes place when freshly mixed mortars come into contact with a porous substrate, such as brick or stone, during on site construction. Since the dewatering process between the mortar and its substrate can modify the mortar properties, understanding the dewatering process enables pozzolan-modified hydrated lime mortars to be optimised for the masonry units being bonded. Evaluation of the water transport kinetics on brick dust—hydrated lime binder systems demonstrated their more water releasing behaviour. Investigations of non-dewatered and dewatered specimens in the volume ratio of 1:1:2 (lime:brick dust:sand) showed that the addition of brick dust to lime mortar increased dewatering, which in turn led to greater compressive strength, carbonation depth, decreased porosity and depth of water penetration. These properties are of great importance in the conservation of historic masonry, as mortars that are too strong or possess low permeability can accelerate degradation. This study will enable identification of the most suitable mix designs thereby increasing the durability and prolonging the life of historic masonry.
The effect of waste-expanded perlite on alkali activation of ground granulated blast furnace slag
Authors: Kucharczyk Sylwia , Pichór Waldemar
Published: March 2023

The purpose of this study was to evaluate the possibility of using ground waste-expanded perlite (WP) as a sustainable replacement for ground granulated blast-furnace slag (GGBFS) precursor in alkali-activated systems. The nature and amount of hydration products, microstructure, and compressive strength development were investigated in mixtures where GGBFS was substituted with 10, 20 and 40% by weight of WP and activated by two alkali activators: sodium carbonate and sodium hydroxide. The results show that WP can be successfully used as a partial replacement for GGBFS in alkali-activated materials. Activation by the Na2CO3 solution was more profitable in terms of compressive strength than NaOH, as well as the amount of water bound in the hydration products was higher. Substitution of GGBFS with 20 wt.% of WP activated with sodium carbonate resulted in a compressive strength of 93 MPa at 90 days of hydration while for the equivalent sample activated by sodium hydroxide, 29 MPa. Further incorporation of WP into Na2CO3 activated systems resulted in a reduction in performance development, especially at the early age. In addition to C–S–H, hydrotalcite, and three different types of carbonates in the samples activated by NaOH solution, a rich in sodium C(–N)–S–H was found.
الاستصلاح الحنفي ومعالمه المقاصدية
Authors: DAKKAK Ümmügülsüm
Published: March 2023

يستهدف هذا البحث إثبات أن الحنفية يأخذون بالاستصلاح ويقولون به وأنه جزء من أصولهم وإن لم يكونوا قد أفردوا ذلك في مبحث خاص من مباحث كتبهم أو مؤلفاتهم، وكذلك من أهداف البحث تبيين معالم مقاصدية الاستصلاح الحنفي وعمق صلة الاستصلاح الحنفي بمقاصد الشرع ومدى الارتباط بينهما، وقد عملت على ذلك من خلال تبيين مفاهيم البحث وهي المصلحة والمقاصد، ثم تحدثت عن حجِّيَّة الاستصلاح في المذهب الحنفي ولخَّصت ما ذُكِر من الأقوال في هذا المجال لقدماء الأصوليين ومعاصريهم، ثم تحدثت عن مظاهر الاستصلاح عند الحنفية من خلال ست نقاط (الملائم المرسل، والاستحسان، والعرف أو العادة، وسد الذرائع، وتخصيص النصوص بالمصلحة، والقواعد الفقهية)، وكانت هذه النقاط المركز الذي استبانت من خلاله نظرية الحنفية في الاستصلاح وتماثلها مع نظرية المالكية، وبعد أن بانت معالم الاستصلاح الحنفي أوضحت موضع اتصال هذه المظاهر بمقاصد الشريعة، وختمت البحث بذكر أمثلة من فروع الحنفية الفقهية تبيَّن من خلالها الاستصلاح الذي عمل به الحنفية ومدى صلته بمقاصد الشرع.
Kariyer Planlama ve Kendini İzleme Açısından Üniversite Öğrencilerinin Karşılaştırılması Üzerine Bir Araştırma
Authors: EREN BANA Perihan , ÖZEK Hande
Published: March 2023

Bu araştırmanın amacı kariyer kararı verme ve kendini izleme konularında sağlık hizmetleri alanında eğitim gören öğrenciler ile diğer bölümlerde eğitim gören öğrenciler arasındaki farkları ortaya koymaktır. Araştırmaya toplam 670 öğrenci katılmıştır. Çalışmada Ulaş ve Yıldırım (2016) tarafından geliştirilen Kariyer Kararı Verme Yetkinliği Ölçeği ve Gültekin (2015) tarafından kullanılan ‘Kendini İzleme Ölçeği kullanılmıştır. Gruplar arası karşılaştırmalara bakıldığında en fazla farklılaşmaya neden olan demografik değişkenlerin sırasıyla cinsiyet, bölümü isteyerek seçmiş olma, daha önce bir üniversite deneyiminin olması, önlisans veya lisans öğrencisi olmak ve sağlık hizmetleri alanında öğrenim görmek olduğu görülmektedir. Kariyer planlama alanında literatürde çok sayıda kaynak bulunmakla birlikte kendini izleme ile kariyer konusunu bir arada ele alan bir araştırmaya rastlanmamıştır. Buradan hareketle, bu çalışmada öğrencilerin kendini izleme ve kariyer kararı verme açısından aralarındaki farklılıkları ortaya koyarak literatüre katkı sağlamak amaçlanmıştır. Ek olarak, öğrencilerin kariyer planlamalarını etkileyen faktörlerin derinlemesine araştırılması, onları daha doğru kariyer seçimlerine yönlendireceğinden, çalışma sonuçları uygulama açısından da önem taşımaktadır.
Machine learning for predicting the survival in osteosarcoma patients: Analysis based on American and Hebei Province cohort
Authors: Hao Yahui , Liang Di , Zhang Shuo , Wu Siqi , Li Daojuan , Wang Yingying , Shi Miaomiao , He Yutong
Published: March 2023

Osteosarcoma, a rare malignant tumor, has a poor prognosis. This study aimed to find the best prognostic model for osteosarcoma. There were 2912 patients included from the SEER database and 225 patients from Hebei Province. Patients from the SEER database (2008-2015) were included in the development dataset. Patients from the SEER database (2004-2007) and Hebei Province cohort were included in the external test datasets. The Cox model and three tree-based machine learning algorithms (survival tree [ST], random survival forest [RSF] and gradient boosting machine [GBM]) were used to develop the prognostic models by 10-fold cross-validation with 200 iterations. Additionally, performance of models in the multivariable group was compared with the TNM group. The 3-year and 5-year cancer specific survival (CSS) were 72.71% and 65.92% in the development dataset, respectively. The predictive ability in the multivariable group was superior to that in the TNM group. The calibration curves and consistency in the multivariable group were superior to those in the TNM group. The Cox and RSF models performed better than the ST and GBM models. A nomogram was constructed to predict the 3-year and 5-year CSS of osteosarcoma patients. The RSF model can be used as a nonparametric alternative to the Cox model. The constructed nomogram based on the Cox model can provide reference for clinicians to formulate specific therapeutic decisions both in America and China.
THEORETICAL BASIS OF DEFINING THE ESSENCE OF ORGANIZATION DEVELOPMENT
Authors:   National University of Food Technologies, Ukraine, Dunda S. , Iakymchuk T. ,   National University of Food Technologies, Ukraine
Published: March 2023

The essence of the concepts “development” and “organization development” has been studied. Three main approaches to development are identified through: study and distinguish system properties; formation of interpretations of this category; comparison of the concept of development with similar categories in terms of scientific knowledge of system behavior. An analysis of the theory of enterprise's development are carried out based on the research of domestic and foreign scientists. As a result of this analysis, specific manifestations of development were identified, and its modern features are studied. The main characteristics of the “development” category are highlighted. The classification features of development in the organization are considered. The main theoretical provisions that form the basis of the development of any organization are presented: the theory of targeted development, the theory of cyclical development, the concept of the life cycle of the organization. It is determined that development in the organization is based on the laws of ontogenesis, composition and proportionality, self-preservation, competition, scale effect, the transition to new scientific approaches and principles, synergy, orderliness, economic laws, the law of development. The factors that determine it are given. It is substantiated that the development of the enterprise is closely connected with its resource potential: the volume of resources possessed by the enterprise has great importance for the growth of the organization, but their presence does not indicate the development. It is noted that the solution to the problems of enterprise's development depends on the management, because economic results are determined by the level of reasonableness of management decisions on taking into account the conditions of production and products' sale, forecasts about their changes in the future. The authors’ definition of enterprise's development is proposed as a set of targeted, intensive and qualitative changes in the economic nature of activity that occur at the enterprise as a result of contradictions in the internal environment and the influences of external environmental factors.
PSYCHOSEMANTIC ANALYSIS OF YOUTH'S PERCEPTION OF MOBILE APP ADVERTISEMENT
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Sosniuk O. P. , Lozovska A. I. ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: March 2023

This article is devoted to exposure of results of psychosemantic analysis of youth's perception of mobile apps oriented on entertainment and study. During empirical study the following methods were used: method of assessment of peculiarities of mobile apps' advertisement, which is based on the semantic differential method, expert interview method, and questionnaire method. The study was conducted during the years of 2021-2022, the sample size consists of 321 people. It was found that in perception of advertisement of mobile apps of entertaining orientation affective components are dominating, the advertising images are generalized and cognitively simple. Factors, which manifest itself during perception of advertisement and define attitude towards it and advertising app were determined. It was also found that in perception of advertisement of mobile apps of educational orientation cognitive and conative components can play a dominant role, advertising images are more specified and cognitively complicated in comparison with perception of advertisement of apps of entertaining orientation. Structure of advertising image can consist of two, or three factors, which define the attitude towards the advertisement and the app being advertised. More differentiated images arise among consumers while perceiving advertisements, that contain more precise and laconic instructions, and informs of the benefits of using this app in educational process. Prospects for further research are determined, which consist in studying the correlation between perception of mobile applications' advertising of entertainment and educational orientation and the motives of consumer behavior of the youth target audience' representatives.
LINKS BETWEEN TRAUMATIC CHILDHOOD EXPERIENCES AND PERSONALITY TOLERANCE IN ADULT AGE
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Kovalenko A. B. , Golota V. G. ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: March 2023

The article justifies theoretically the problem of traumatic childhood experience and its connection with personality tolerance in adulthood. A childhood trauma has certain effects on occurrence of depression, anxiety, neuroticism, cognitive disorders, on a tendency to commit suicide or use psychotropic substances, as well as on worldview, relationships with other people and the quality of life in adulthood, which has been theoretically substantiated. The performed empirical study indicated that a significant part of the examined people had traumatic childhood experiences: lack of food; bullying and physical violence by adults or peers; loss of one or both parents; living with a person who had mental disorders; physical violence between parents or guardians; lack of love from parents or existing feeling of own uselessness; sexual harassment or sexual violence. In adulthood, these people were prone to trauma: humiliation, deprivation, betrayal, abandonment, injustice. Childhood traumatic experiences are associated with certain types of tolerance. The absence of one parent is associated with emotional instability; physical violence and bullying by peers correlates with intolerance to uncertainty; certain types of a parent’s addiction is linked with the child’s conservatism; an imprisoned parent is associated with the desire to make an individual’s partner comfortable to him/her, practical approach to partners; feeling of being unloved by parents correlates with detachment from others. Childhood humiliation, physical abuse by parents and bullying by peers are associated with uncertainty intolerance in adulthood. Experienced betrayal, feelings of unloved are associated with conservatism, detachment from others and the desire to make other people more comfortable for oneself. In general, a traumatic childhood experience can determinate a tendency to social anxiety, low self-esteem, tolerance for the peculiarities of others, many social fears, an inability to listen to oneself, pessimism, as well as an inability to forgive mistakes and detachment from others because of the fear to re-experience betrayal from a loved one.
RECIPROCITY OF EXPRESSED EMOTIONS IN THE TRIAD «MEDICAL SERVICE USER-FAMILY MEMBERS-HEALTHCARE STAFF»
Authors:   Municipal Institution Of Higher Education «Volyn Medical Institute» of The Volyn Oblast Counsil, Pastryk T. V.
Published: March 2023

The paper aims to explore theoretically and empirically the reciprocity of expressed emotion (EE) in the interaction of medical service users with chronic gastrointestinal diseases, their relatives and healthcare staff. The key research question was whether the objective emotions expresses by relatives and healthcare staff coincided with subjective EE experienced by medical service users. The study applied methods of theoretical analysis, as well as measures, represented by scales and questionnaires for empirical research, including the Health-Related Quality of Life Questionnaire (EQ-5D-3L), the Level of Expressed Emotion Scale (LEE), the Family Attitude Scale (FAS), the perceived Expressed Emotion in Staff Scale (pEESS). According with the goal, the study aimed to solve the following research questions: Are there any correlations (as markers of EE reciprocity) between EE as the family's objective attitude to a diseased medical service user and the user's subjective experience of such family's and healthcare staff's attitude to him/her? Can the family attitudes towards a medical service user with chronic gastrointestinal diseases, the subjective experience of this attitude by the medical service user (perceived emotions expressed by the relatives), the user's subjective experience of the healthcare staff's EE and the user's health condition become predictors of disease-related quality of life? Are there any differences in health condition and disease-related quality of life according to the status of a family member (a partner/other relative)? The study results indicate that there were significant correlations between the perceived EE as a marker of subjective experiences of relatives' EE and objective family attitude towards medical service users. The findings also indicate correlations between family member's and healthcare staff's EE as it was perceived by medical service users. These results showed the reciprocal character of EE as a marker of a diseased individual's family environment. The results of the linear multiple regression showed that FAS as a marker of the family's attitude towards medical service users and users' health condition were significant predictors of life quality related to gastrointestinal diseases. There were significant differences between the objective family attitudes towards medical service users depending on caregivers' family status, in particular, FAS was higher in partners compared to other caregivers.
ADAPTATION OF THE BENIGN AND MALICIOUS ENVY SCALE (BeMaS) INTO THE UKRAINIAN LANGUAGE: PSYCHOMETRIC INDICATORS ANALYSIS
Authors:   Ukrainian Catholic University, Pylat N. І. , Haletska I. І. ,   Ivan Franko National University of Lviv
Published: March 2023

The aim of the work is to test and validate the Benign and Malicious Envy Scale (BeMaS) (Lange & Crusius, 2015) among a Ukrainian sample. The study involved 484 people aged 17 to 58 years (M = 24.5), 17.2% men and 82.8% women. The α-Cronbach index for BeMaS is 0.83 for the benign envy scale and 0.84 for the malignant envy scale, indicating a high level of homogeneity. As a result of exploratory factor analysis and confirmatory CFA analysis, two factors were identified in the BeMaS methodology: benign and malignant envy. The two-factor structure is consistent with conceptualizing envy not as a unidimensional construct, but as a two-dimensional construct that includes a benign and a malicious form of envy. Researchers suggest distinguishing malicious envy, which is characterized by hostility toward others of higher status, and benign envy, which motivates people to self-improvement instead of causing feelings of ill will (Crusius and Lange, 2014; Falcon, 2015). Both subscales were found to be reliable and internally consistent. The test reliability of BeMaS testifies to the high level of reliability of the Ukrainian version. The benign envy scale shows direct correlations with constructive coping (positive reformulation, personal growth, active coping, use of emotional social support), and personal resilience. Instead, the malicious envy scale has direct correlations with destructive coping strategies, including negative venting, denial, behavioral avoidance, and self-blame, as well as a direct correlation with depression and an inverse correlation with resilience. Both benign and malicious envy scales are directly related to narcissistic personality strategies: admiration and rivalry. BeMaS has a two-factor structure, good internal, discriminant, and predictive validity, and can serve as a measure of envy in Ukrainian.
Investigation of the Analgesic Properties L-759,633 and SER 601 in Experimental Neuropathic Pain Model in Rats and their Comparison with Pregabalin
Authors: Joha Zıad , Yıldırım Şahin , Hacısüleyman Levent , Taşkıran Ahmet Şevki
Published: March 2023

Despite the fact that narcotics and NSAIDs are the mainstays of nociceptive pain care, only a small proportion of neuropathic pain patients benefit from them. Cannabinoid agents could be a viable alternative to opioids in the management of chronic pain. The goal of our investigation was to assess the analgesic efficacy of SER 601 and L-759,633, cannabinoid receptor 2 (CB2) agonists, at various doses in a model of neuropathic pain generated in rat. The analgesic effect of CB2 agonists L-759,633 and SER 601 at various doses in a rat model of neuropathic pain created by partial sciatic nerve ligation was examined by the hot plate method. Furthermore, a comparison of analgesic effects of both drugs with pregabalin is also conducted. The two substances demonstrated a dose-dependent analgesic effect in this model. The analgesic response of SER601 and L-759,633 in the neuropathic pain model was higher compared to that of pregabalin. All in all, our data suggest that SER601 and L-759,633 may offer a beneficial treatment option for neuropathic pain in future.
Structural, Electronic, ADME and p450 Analyses of Boron Containing Compounds against Omicron Variant (B.1.1.529) in SARS-CoV-2
Authors: Sayın Koray , Ataseven Hilmi
Published: March 2023

Eight boron compounds are investigated in this study. Structural and spectral characterization is done at M062X/6-311G(d) level in the water. Active sites of these compounds are determined using contour plots of frontier molecular orbital, molecular electrostatic potential (MEP) maps and MEP contour.. Electrophilic and nucleophilic attack regions are determined. We aimed to determine whether boron compounds inhibitor used in the treatment of omicron variant of SARS-CoV-2. Since SARS-CoV-2 is a worldwide health problem, anti-viral properties of studied boron compounds were investigated using in silico techniques. Bioavaliability analyses were performed using ADME and p450. It was found that compound B7 can be good drug candidate against omicron variant of SARS-CoV-2.
On Solutions Of Random Partial Differential Equations With Laplace Adomian Decomposition Method
Authors: Merdan Mehmet , Atasoy Nihal
Published: March 2023

In this study, random partial differential equations obtained by randomly choosing the coefficients or initial conditions of partial differential equations will be analyzed. With the help of Laplace Adomian Decomposition Method and Homotopy Analysis Method, approximate analytical solutions of random partial differential equations were obtained. Initial conditions and parameters are made into random variables with normal distribution and gamma distribution. Probability characteristics such as expected value, variance and confidence intervals of the obtained random partial differential equation are calculated. Obtained results will be plotted with the help of MATLAB (2013a), package program and random results will be interpreted.
Screening of Probiotic Properties of Bacillus Licheniformis Isolated from Yoghurt
Authors: Kocabay Samet
Published: March 2023

Probiotic microorganisms are an indispensable part of a healthy life. The usage areas of the probiotic Bacillus licheniformis bacteria are quite wide, from contributing to the development of the immune system to reducing cholesterol, which is an important cause of cardiovascular diseases. In this study, Bacillus licheniformis (isolate 29) was isolated from traditional yoghurt sample obtained from town of Hatipli/ Tokat/ Türkiye. And it’s genotypic and probiotic characterizations were performed. Our results showed that the isolated Bacillus licheniformis grew better at pH 5. The survival rate of the bacteria in artificial gastric and intestinal fluid was determined as 47.51% and 65.29%, respectively. The isolate degraded all tested sodium salts, including Sodium glycocholate hydrate, Sodium taurodeoxy Cholate, Sodium taurocholic acid, Sodium tauroglyco Cholate, Sodium thioglycolate. Its surface hydrophobicity was found to be moderately 30.31 ± 0.009% in n-Hexadecane. Although RA5 antibiotic had the largest zone diameter (10 mm), antibiotic susceptibility of Bacillus licheniformis was not among the antibiotic discs tested. These findings indicated that the isolate can be a good probiotics candidate to lower the cholesterol levels.
Investıgatıon of the Effects of Favipiravir and Oseltamivir Active Substances Used in the Treatment of Covid-19 on Carbonic Anhydrase I-II Isoenzymes and Acetylcholine Enzyme Activities in Vitro
Authors: Arık Sueda , Koçyiğit Ümit Muhammet
Published: March 2023

Covid-19, originating from Wuhan, China, is a worldwide health problem. Immune system abnormalities caused by covid-19 lead to infections, septic shock, and severe multi-organ dysfunction. The drugs used for treatment are palliative pharmacological alternatives and help manage symptoms or complications that occur during the course of the disease. Both carbonic anhydrases and cholinesterases can be target enzymes for drugs. The goal of this study is to determine how the drugs used in covid-19 affect patients being treated for Alzheimer's disease, myasthenia gravis, glaucoma, or epilepsy, and to determine if there are drug-drug interactions. In case of possible interactions, it is crucial for these patients to consider alternative treatments and to recheck the dosage of the drugs used. To this end, the effects of the drugs favipiravir and oseltamivir, which are used in the covid-19 clinic and whose relationship with these enzymes has not been previously studied, on the isoenzymes of carbonic anhydrase I- II and the enzyme acetylcholinesterase were studied in vitro. No inhibition or activation was observed on the enzyme acetylcholinesterase, while inhibition was observed for the isoenzyme carbonic anhydrase I - II.
Toll-like Receptor 3 c.1377C/T and -7C/A Polymorphisms Associated with COVID-19 and COVID-19 Severity
Authors: Özbilüm Nil , Bayyurt Burcu , Arslan Serdal , Baltacı Sevgi , Bakır Mehmet
Published: March 2023

Chinese officials have reported the novel coronavirus to the world health organization, which is called the SARS-CoV-2. Toll-like receptor 3 (TLR3) induces antiviral immune responses via the production of type I interferons and inflammatory cytokines. In this study, we aimed to examine TLR3 c.1377C/T and -7C/A polymorphisms in COVID-19 and the association between some clinical parameters. We investigated the frequencies of TLR3 (c.1377C/T and -7C/A) polymorphisms in 150 patients with COVID-19 and 171 healthy individuals as controls. We performed polymerase chain reaction (PCR) based on restriction fragment length polymorphism (RFLP). We also investigated whether TLR3 c.1377C/T and-7C/A were associated with the severity of COVID-19. In addition, CHAID tree-based classification algorithm was created to investigate the severity of the patients in our study. TLR3 c.1377C/T TT genotype frequencies were statistically significant between cases and controls (p= 0.02). For TLR3 -7C/A polymorphism, the findings showed a statistically significant difference in A allele frequencies (p= 0.03). There was a statistically significant difference in the distribution of TLR3 -7C/A CA genotype frequency (p= 0.04). Our findings suggest that TLR3 c.1377C/T and -7C/A polymorphisms may be important on susceptibility or clinical course of COVID-19.