bluuebunny/crossref_metadata_2025 huggingface dataset:
Reality of ‘Enjoyable Life’ of the Elementary School in a Historical Viewpoint of Music Education
Authors:   Korean Music Education Society, Ju Dae Chang
Published: June 2024

This research proceeds from posing a question whether the ‘enjoyable life’ in Korea is justified from a vantage point of music education. The writer highlights historical contexts between the general school music class and the ‘enjoyable life’ as an integrated subject. And then, the curricular for the ‘enjoyable life’ are analytically examined for the connection between music class and the ‘enjoyable life’. In ancient times, a comprehensive music education was recommended as it is shown in works of Confucius or Plato. Music was also a significant subject matter in elementary schools in the Christian culture where singing hymns established an educational tradition as a process of socialization. However an aesthetic and humanistic approach, for example by Rousseau or Pestalozzi, is regarded as the cornerstone of modern music education in elementary school. The ‘enjoyable life’ in Korea emerged in 1980s which seemingly succeed to traditional music class, and eventually claimed an independent subject, but from the perspective that music curricula can lead holistic development in children, it has been unsuitable for integrative education. Thus, the writer proposes to restore the music class instead of ‘enjoyable life’ in elementary school and to enhance teaching methods for integrated music education.
An Investigation on Music Teachers' Perception of Music Education as an Ecological Transformation Education
Authors:   Korean Music Education Society, Park Songhee
Published: June 2024

This research aims to propose a direction for ecological music education through an investigation on music teachers’ perception regarding music education as an ecological transformation education. The research was carried out by analyzing literature related to ecological music and conducting a survey on ecological music education of 321 music teachers. The data was analyzed by SPSS 29, conducting frequency analysis and descriptive statistics. Additionally, the t-test and linear regression analysis were carried out to explore the relationship between teachers’ background and their perception of ecological music education. The result demonstrated that music teachers positively perceived a potential behind music as an ecological transformation education, believing music and ecology were related, and therefore music could be used to resolve ecological crisis. Furthermore, although many teachers didn’t teach music classes related to ecology, most of them had willingness to receive training about it. On the other hand, they indicated a need for standardization of terminology such as ‘ecological music’, an introduction of example cases for ecological music classes, and the development of ecological music education programs. Also, perceiving that the workplace was nature-friendly had a positive impact on perceiving that music and ecology were related.
Isolation and characterization of plant growth promoting rhizobacteria (PGPR) from rhizosphere of Helianthus annuus L.
Authors: Güler Murat , Öğütcü Hatice
Published: June 2024

Plant growth-promoting rhizobacteria (PGPR) support plant growth through direct and indirect mechanisms. To investigate PGPR strains that support plant growth, 21 bacterial isolates, mostly Bacillus ssp. and Pseudomonas ssp., were isolated from different rhizospheric soils of sunflowers in Kırşehir districts in 2020. All isolates were characterized morphologically, biochemically by screening under in vitro conditions for plant growth-promoting properties such as nitrogen fixation, IAA (indoleacetic acid) production, siderophore production, HCN (hydrogen cyanide) production, inorganic phosphate solubility. It was also screened for extracellular enzyme production and antifungal activity against Fusarium oxysporum. Among the 21 isolates, 3 isolates (MH-35-4, MH-49-4, MH-64-3) fixed nitrogen, 2 isolates (MH-59-6, MH-64-3), produced siderophores, 8 isolates (MH-35-4, MH-35-6, MH-54-3, MH-54-4, MH-59-1, MH-59-2, MH-59-4, MH-59-8) produced HCN, 6 isolates (MH-35-6, MH-54-4, MH-59-1, MH-59-2, MH-59-4, MH-59-8) produced IAA, and 7 isolates (MH-35-4, MH-35-6, MH-59-1, MH-59-2, MH-59-4, MH-59-8, MH-64-3) solubilized inorganic phosphate. Additionally, only 2 isolates (MH-54-3, MH-54-4) were positive amylase tests, 8 isolates (MH-35-6, MH-54-4, MH-59-1, MH-59-2, MH-59-4, MH-59-6, MH-59-7, MH-59-8) were positive citrate tests, 8 isolates (MH-35-1, MH-35-4, MH-35-7, MH-49-4, MH-54-4, MH-59-6, MH-59-7, MH-64-3) were positive protease tests, and 6 isolates (MH-35-1, MH-35-3, MH-35-7, MH-54-3, MH-54-4, MH-59-7) were positive gelatin hydrolysis tests. Among 21 isolates, 38% were determined as hydrogen cyanide producers, 10% as siderophore producers, 29% IAA producers, 33% as phosphate solubilizers and 14% as nitrogen fixers. Isolate MH-35-6 showed the highest antifungal activity against Fusarium oxysporum with an inhibition rate of 53.57%. This was followed by isolates MH-54-1 (51.19%), MH-54-3 (47.61%) and MH-59-2 (38.09%), respectively. Therefore, our study reveals that bacteria that promote plant growth in sunflowers can be used to increase crop yield and as a biocontrol agent.
Method for assessing the quality of dispersion of polymer composite solutions
Authors:   Lipetsk State Technical University, Lee R.I. , Kiba M.R. ,   St. Petersburg Mining University, Erokhin V.E. ,   Lipetsk State Technical University
Published: June 2024

The use of polymer nanocomposites when restoring worn-out body parts significantly increases their service life and significantly reduces the cost of repairing equipment. With a uniform distribution of filler particles in the solution, the highest mechanical and thermophysical properties of the polymer composite are achieved. A new method has been developed and proposed in which the quality of mixing a polymer composite solution is assessed by the uniformity of the distribution of filler particles in the solution. The method is characterized by efficiency and increased reliability of mixing quality control, reduced material consumption and low cost.
Participants use a mixture of strategies to solve sequential decision problems
Authors: Furl Nicholas , van de Wouw Didrika Sahira , McKay Ryan
Published: June 2024

Full-information best choice problems typify many real-world decisions. Participants face a sequence of decision options and must accept or reject each option at the time it is encountered. The challenge is to use prior knowledge of the distribution of option values to predict whether continued sampling might result in a higher-valued option than the one currently on offer. On these tasks, biases are apparent when human decisions are compared against mathematical optimality solutions. Specifically, tasks involving choices about options presented as images appear to evoke an oversampling bias, in which participants perform suboptimally by rejecting optimal choices and continuing to sample new ones. Using computational modelling of ten datasets spanning five choice domains, we demonstrate two dominant sampling strategies. These strategies, which explained the overly long searches, involved a combination of overly optimistic predictions about future option values and an intrinsic perception that sampling itself has reward value. These strategies, and their associated systematic biases, could manifest in real-world decisions such as shopping, choosing dating partners or trustworthy job candidates.
Not feeling like winners: The higher educated and the AI revolution
Authors: Knotz Carlo Michael
Published: June 2024

Technological redundancy was so far seen as mainly a concern for lower to medium educated workers, but recent advances in machine learning and algorithmic decision-making technology – i.e., “artificial intelligence” (AI) – have raised concerns that the higher educated could now be affected as well. Adding to an emerging literature on the effects of AI exposure, I show that higher educated workers indeed feel that they are at risk of technological redundancy, and that these perceptions are related to objective exposure to AI technology. Specifically, I combine comparative survey data on workers’ subjective technological vulnerability with indicators of objective industry-level AI exposure and find a U-shaped pattern among higher educated workers: There is high perceived vulnerability in some “traditional” automation-exposed sectors (e.g., manufacturing) but also in a group of strongly AI-exposed white-collar industries (finance, real estate, IT), with a remaining pocket of low vulnerability in strongly interpersonal sectors (e.g., education, healthcare). These findings have broader societal and political implications, namely that further advancement in AI technology may contribute to a de-polarization of social risk and thus create the basis for new cross-class coalitions and social solidarity – but it may also reinforce current authoritarian tendencies.
Socioeconomic Variables Enhancing Prevalence of Diabetes Disability in Bangladeshi Adults of High Normal and Hypertensive Blood Pressure
Authors: Bhuiyan K. C.
Published: June 2024

The present analysis was based on data collected from rural and urban Bangladeshi 995 adults of 18 years and above. The investigation was done to observe the prevalence of diabetes-disability in respondents of high normal and hypertensive blood pressure. Prevalence was noted in 9 such adults; among them 7 were males and 2 were females. The sample contained males and females in the ratio 50.1: 49.9. The respondents were interviewed during their visit in some diagnostic centres of urban and semi-urban areas. The sample diabetic adults were 67%. Among them who were suffering for 10 – 15 years the percentage of diabetic disable adults of higher blood pressure were 5.1%. For this group the risk of prevalence was 11.31 times. Higher risk was also noted among elderly adults and adults of high economic status. The most responsible variable which enhanced diabetes disability was duration of diabetes. The other enhancing variables were age, body mass index, and sedentary activity. These were identified on the basis of significant correlation coefficient of the variables and discriminant function score. However, rural people, males, illiterate people, housewives, adults of high economic status, had higher risk of prevalence. These were identified from the values of risk ratios. Beside these, the other responsible variables for enhancing the prevalence of the disease were habit of taking process food, and physical inactivity.
Early Breast Cancer Fast Facts: Results, Recurrence, Resources
Authors: Hunis Adrian
Published: June 2024

Despite successful treatment, there is always a risk of recurrence in early breast cancer. The risk of recurrence varies depending on various factors such as the size of the tumor, lymph node involvement, hormone receptor status, and other individual characteristics.
Violencia política en contra de las mujeres en razón de género
Authors:   Ventanilla Única. Centro del InstitutoNacional de Antropología e Historia (INAH) Chiapas.Tuxtla Gutiérrez, Chiapas. México, Sánchez Calderón Esperanza
Published: June 2024

Como ya es costumbre, al inicio de año, nuestros superiores jerárquicos nos “invitan” a tomar, aprobar y comprobar con la constancia correspondiente, cursos relativos al área que desempeñamos, pero específicamente los que tienen relación con la violencia hacia las mujeres o con perspectiva de género. Para las próximas elecciones, la sugerencia propuesta del curso fue el título “Violencia Política en Contra de las Mujeres en Razón de Género, Delitos Electorales”. Con suma desolación observo que las que cumplimos en tomar el curso somos las mujeres, pareciera que somos las únicas que tenemos que conocer la legislación para hacer valer un derecho que no se tendría que hacer valer, si todos respetáramos que, si tienes la capacidad de ostentar un puesto público con la debida diligencia, lo puedes ocupar siendo mujer u hombre. Por lo tanto, esas constancias solo engrosan un currículum o adornan una pared, porque a pesar de los cursos, no se aplica la normatividad y cuando quieres ejercer efectivamente estos derechos te desestiman, te anulan, menoscaban, porque los superiores jerárquicos que son hombres no tomaron el curso y no saben que están incurriendo en alguna violación de derechos.
Deficiency of factor VII (hypoproconvertinemia): case report
Authors:   Ryazan State Medical University, Ryazan, Russian Federation, Dmitriev A.V. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Fedina N.V. ,   Ryazan State Medical University, Ryazan, Russian Federation, Yudakova M.S. ,   N.V. Dmitrieva Regional Children's Clinical Hospital, Ryazan, Russian Federation, Dronova S.N. ,   N.V. Dmitrieva Regional Children's Clinical Hospital, Ryazan, Russian Federation, Slabachkov K.O. ,   Ryazan State Medical University, Ryazan, Russian Federation, Zaplatnikov A.L. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
Published: June 2024

Factor VII (proconvertin) is a pivotal initial step in the activation of the extrinsic pathway of blood coagulation. Factor VII deficiency is a rare coagulopathy that can manifest in a wide range of clinical symptoms, from asymptomatic deficiency to severe hemorrhagic syndrome, which can often lead to death due to hemorrhages, including brain hemorrhages. The article provides a brief overview of the epidemiology of the disease, its clinical manifestations, diagnostic approaches, and treatment options. The authors present a case of relatively late diagnosis of hypoproconvertinemia, which manifested with severe bleeding in the neonatal period. In the first year of life, the child experienced recurrent hemorrhagic syndrome, which was managed by administering menadione sodium bisulfite trihydrate solution. Examination did not reveal deficiency of factor VIII or IX. The diagnosis was established at the age of 3 years, and the child received recombinant factor VII. However, on- demand therapy and the lack of long-term preventive administration of the drug did not provide a sufficient hemostatic effect, as evidenced by repeated episodes of hemarthrosis and severe gastrointestinal bleeding at the age of 15 years These complications necessitated a switch to continuous administration of recombinant factor VII. KEYWORDS: hypoproconvertinemia, hemophilia, children, bleeding, recombinant FVII. FOR CITATION: Dmitriev A.V., Fedina N.V., Yudakova M.S., Dronova S.N., Slabachkov K.O., Zaplatnikov A.L. Deficiency of factor VII (hypoproconvertinemia): case report. Russian Journal of Woman and Child Health. 2024;7(2):184–188 (in Russ.). DOI: 10.32364/2618- 8430-2024-7-2-15.
ntrauterine fetal surgery of urinomas: outcome analysis
Authors:   Research Institute of Maternity and Infancy Protection, Ekaterinburg, Russian Federation, Kosovtsova N.V. , Fedorova N.A. ,   Research Institute of Maternity and Infancy Protection, Ekaterinburg, Russian Federation, Pospelova Ya.Yu. ,   Research Institute of Maternity and Infancy Protection, Ekaterinburg, Russian Federation
Published: June 2024

Aim: to analyze the outcomes of intrauterine fetal surgery of urinoma and discuss obstetric tactics Patients and Methods: in the conditions of the Research Institute of Maternity and Infancy Protection, 12 cases of fetal urinoma were diagnosed in the period from 2018 to 2021. Ultrasound and doppler ultrasound of the kidneys were performed on all fetuses, and MRI was additionally used. In the postnatal period, a complete clinical laboratory and ultrasound examination of fetuses was performed to assess the preservation of kidney function Results: the mean gestation period at the time of urinoma diagnosis was 20.9±1.9 weeks. The period of admission to the hospital was 24.8±2.3 weeks. The average size of the detected urinoma in fetuses: longitudinal — 57.5±2.75 mm, transverse — 36.5±2.7 mm (maximum size 94×71 mm). In all cases, compression of adjacent organs was observed with large amounts of urinoma. When assessing renal blood flow, it was visualized only in 25% of cases. All patients with large urinomas in the fetus underwent intrauterine bypass surgery using the SDE-MED stent with the original pigtail shape (utility model patent No. 152166, 2015). In 72.7% (8) of cases, chronic renal failure was formed in the born children, and only in 27.3% (3) of cases, fetal renal function with urinomas remained intact. Conclusion: in the early diagnosis of obstructive malformations in the fetal urinary system, the intrauterine bypass surgery in the renal cavitary system prevents the urinoma occurrence and preserves kidney function, which reduces the risk of renal failure in an infant. In urinoma in the fetus, especially large ones, intrauterine bypass surgery is necessary to decompress adjacent organs and preserve kidney function. However, it is worth noting that kidney function after the birth of an infant with this pathology can be preserved only in a quarter of all cases KEYWORDS: congenital genitourinary anomalies, kidney function, obstructive uropathy, fetal urinoma, intrauterine bypass surgery, renal failure. FOR CITATION: Kosovtsova N.V., Fedorova N.A., Pospelova Ya.Yu. Intrauterine fetal surgery of urinomas: outcome analysis. Russian Journal of Woman and Child Health. 2024;7(2):104–109 (in Russ.). DOI: 10.32364/2618-8430-2024-7-2-3.
CAR-T immunotherapy - recent advances and current challenges in cancer treatment: a review.
Authors: Ronowicz-Pilarczyk Joanna
Published: June 2024

Adoptive cell therapy represents a modern immunotherapeutic approach utilizing immune cells as dynamic agents against cancer cells, often called "living drugs". In recent times, chimeric receptor antigen T cell (CAR-T cell) therapy has shown efficacy and promise in the immunotherapy of cancers, presenting a significant advancement in blood cancer treatment. However, despite its effectiveness in treating B-cell lymphoma, challenges persist with response variability, resistance, and adverse effects. This review focuses on recent advances and current challenges, limitations, and the related preclinical and clinical findings of cancer immunotherapy as well as solutions for increasing the safety and effectiveness of CAR-T cell therapy. Ongoing research focuses on exploring molecular and cellular processes post-infusion, developing "universal CAR-T lymphocytes" sourced from healthy donors as well as exploring alternative candidates like CAR-armored NK cells and CAR-NKT cells, which show promise due to their potent anti-tumour properties and diverse cytotoxic capabilities. The interplay of genetics with the immune system undoubtedly holds the potential for developing innovative treatments that could revolutionize cancer therapy in the future.
The Impact of Data-Driven Decision Making on the Annual Net Sales Revenue and Stock Price of Amazon: A Study from 2004 to 2022
Authors: Oluwafisayo Fakinlede
Published: June 2024

In the rapidly changing world of e-commerce, data-driven decision making now stands out as a critical approach for businesses that seek to excel and stand out among the crowd of competitors. This paper covers the results of data-driven decision making on Amazon's annual net sales revenue over the years 2004 through 2022. Amazon is a multi-billion dollar company that operates in the online retail space as one of the largest encompassing platforms in the world. Through both secondary data taken from Yahoo Finance and Statista, this investigation accomplishes a longitudinal analysis to find out the connection between approaches and financial data, specifically the connection between Amazon's data-driven approaches and its net sales revenue and stock price. This study reveals a data-reliant decision-making approach and a shift towards e-commerce business in light of the contemporary progress of automated analytics on business strategies.
Study of restoration of body parts of automobile engines by the method of electric arc metalization
Authors:   Poltava State Agrarian University, Ivankova Olena , Burlaka Alexei ,   Poltava State Agrarian University
Published: June 2024

Road transport ensures a rational organization of production and transportation of products. The cylinder block is a basic part, mechanisms and engine parts are attached to it. Engine blocks are operated with high loads. Defects arise and develop, which can be eliminated during major repairs. Improving the methods of restoring worn cylinder blocks of automobile engines is an urgent task. The possibility of restoring parts with such defects by gas-thermal methods was considered. The total level of defects that can be eliminated by applying a restorative coating by the method of electric arc metallization is 37%. The analysis of literary sources shows that surfacing and welding methods do not ensure the quality of the restored part. Gas-thermal methods are often used in the process of repairing parts. The most technological and effective is electric arc metallization. Productivity of electric arc metallization can be very high. Operating costs of using electrometallization are small. The equipment is relatively simple. Restoration of parts by electric arc metallization increases wear resistance and durability of the engine. To assess the repeatability of block defects, we analyzed a sample of 20 truck cylinder blocks from different manufacturers. It was established that the resource of the block depends on: wear of the main bearing beds, holes, cracks, damage to the thread and breakage of pins and holes. Laboratory experiments on the application of electroplating coating were carried out on samples of high-strength cast iron. Preparatory processing of samples - shot blasting. Experiments on sputtering of samples were carried out with known powder wires PG-SR4 and PG-SR4+3% Al with a diameter of 2.0 mm. Spraying was carried out with an EM-17 electric arc metallizer. Tests on the adhesion strength of the coating to the base metal were carried out using the adhesive method. From the research results, we can see that the coating applied with PG-SR4+3%A1 wire is destroyed at the joint under a higher load than the corrosion formed by PG-SR4 wire. At the same time, the adhesion strength also exceeds, and is 22.9 MPa. The microhardness of the coating built up with powder wire PG-SR4+3%A1 exceeds the level of microhardness of the surface built up with wire PG-SR4. Microhardness in both cases. decreases with distance from the surface of the deposited layer. Conclusions. From the conducted research, it follows that the electric arc restoration does not have a thermal effect on the part, provides high adhesion strength of the applied layer, which prevails over the majority of traditional methods of restoration of parts. In addition, the method of electric arc metallization is characterized by low energy consumption, small-sized and mobile technological equipment. Therefore, there is a need to continue the research of electric arc metallization in the restoration of worn surfaces of car parts.
The research of ways of efficiency increasing of electronic car system diagnostic operations
Authors:   Central Ukrainian National Technical University, Krasota Mykhailo , Kuleshkov Yuriy ,   Central Ukrainian National Technical University, Shepelenko Igor ,   Central Ukrainian National Technical University, Osin Ruslan ,   Central Ukrainian National Technical University, Rudenko Timofey ,   Central Ukrainian National Technical University
Published: June 2024

The purpose of this study is to find ways to reduce production time spent on diagnostic operations during maintenance or repair of electronic control systems (ECS) in automotive vehicles. Existing methods of diagnosing engine control systems in vehicles are sufficiently effective, but in most cases, they require highly skilled personnel, the use of additional complex and expensive equipment, prolonged service cycles, which in turn increases the complexity of maintenance, and also does not provide for prior prediction of faults and system failures. Analysis of scientific publications has shown that to reduce the time for maintenance and repair of electronic systems, it is necessary to predict the residual life of ECS components in vehicles during maintenance, to further reduce the labor intensity of diagnostics and current repairs. In other words, diagnostics performed during maintenance or repair should include predicting the residual life of electronic system components. For the most critical ECS components in vehicles, it is proposed to apply a strategy of replacing them upon reaching a certain mileage, rather than upon failure. This organization method will reduce vehicle downtime in repair and reduce the time to troubleshoot ECS component failures. A method has been proposed for identifying design elements that limit the reliability of the ECS, taking into account the degree of influence of their failures on the engine's technical and economic characteristics and the cost of restoring its performance. The availability of such information is the basis of the ECS maintainability support system. An algorithm has been developed to search for hidden faults in the components of ECS subsystems, which includes predicting the failure of ECS components. This will help reduce the labor intensity of diagnostic operations during maintenance and repair.
Methodology for calculating the main characteristics of sliding bearings of car systems and units and analyzing their tribological efficiency
Authors:   Central Ukrainian National Technical University, Aulin Viktor , Kuzyk Oleksandr ,   Central Ukrainian National Technical University, Lysenko Serhii ,   Central Ukrainian National Technical University, Hupka Andrii ,   Ivan Pulyuy Ternopil National Technical University, Hrinkiv Andrey ,   Central Ukrainian National Technical University, Zhilova Inna ,   Central Ukrainian National Technical University
Published: June 2024

A methodology for calculating the main characteristics of sliding bearings of car systems and units is proposed. The specified methodical approach is important when evaluating indicators of tribological efficiency of couplings of parts, nodes, systems and aggregates and operational reliability of cars as a whole. The bearing activation model makes it possible to formulate measures to increase the tribological efficiency of the couplings of parts and the level of operational reliability of nodes, systems and aggregates, and cars as a whole. In addition, the parameters of the actuation model also respond to friction modes. It is shown that it is possible to increase the tribological efficiency of the sliding bearing by means of design, technological and operational methods. The main formulas that make it possible to develop algorithms for calculating a set of bearing characteristics are presented: contact pressure, stress, strength, sliding resistance, wear, resource. For this purpose, the following values are used: compliance coefficients and relative load, contact angle, contact pressures, contact displacements, and the stress state in the contact zone. The geometric and power parameters of the bearing are involved in the developed methodology and algorithm. Modes of friction and the nature and magnitude of the load on the bearing are also taken into account. An algorithm for calculating auxiliary and main characteristics of a sliding bearing has been developed. The conditions of continuity and equilibrium in contact are clarified. The differential-integral equation of the operation of the bearing is obtained and the dependence of the current contact angle on the friction path and other parameters of the sliding bearing operation model is obtained. It is shown that the tribological efficiency of sliding bearings is established by the method of comparative analysis of tribotechnical characteristics determined by the results of tests on friction machines and a stand.
Sono-hydrogen: a Theoretical Investigation of its Energy Intensity
Authors: Al-Awamleh Ahmad , Hegedűs Ferenc
Published: June 2024

The present paper investigates the energy efficiency of hydrogen production by a freely oscillating microbubble placed in an infinite domain of liquid water. The spherical bubble initially contains a mixture of argon and water vapour. The bubble is expanded from its equilibrium size to a specific maximum radius via an isothermal expansion. The work needed to expand the bubble is its potential energy calculated by the sum of the work done by the internal gas, the work needed to displace the mass of the surrounding liquid, and the work needed to increase the area of the bubble against the surface tension. During the radial pulsation of the freely oscillating bubble, the internal temperature can reach several thousands of degrees of Kelvin inducing chemical reactions. The chemical yield is computed by solving a set of ordinary differential equations describing the radial dynamics of the bubble (Keller—Miksis equations), the temporal evolution of the internal temperature (first law of thermodynamics), and the concentration of the chemical species (reaction mechanism). The control parameters during the simulations were the equilibrium bubble size, initial expansion ratio, ambient pressure and temperature, the accommodation coefficient of the evaporation/condensation and the surface tension. In the best-case scenario, the energy requirement is 4072.3 MJ/kg.
Validitas kontrol diri dalam memoderasi perilaku pembelian impulsif siswa sekolah menengah atas
Authors: Murniawaty Indri , Sari Nurul Aisah Lancar , Farliana Nina
Published: June 2024

Tujuan dari penelitian ini adalah untuk menganalisis pengaruh penggunaan media sosial dan konformitas terhadap pembelian impulsif dengan kontrol diri sebagai variabel moderasi di SMA Negeri Se-Kabupaten Rembang. Jenis penelitian ini menggunakan pendekatan kuantitatif. Populasi penelitian ini sebanyak 3.048 siswa. Sampel pada penelitian sebanyak 100 siswa. Metode pengambilan sampel menggunakan probability sampling dengan teknik proportional random sampling. Teknik pengumpulan data menggunakan kuesioner. Teknik analisis data mengunakan statistik deskriptif dan Structural Equation Modelling (SEM) berbasis PLS. Hasil analisis deskriptif, kategori variabel pembelian impulsif dan konformitas cukup, sedangkan kategori variabel penggunaan media sosial dan kontrol diri tinggi. Hasil penelitian menunjukkan bahwa penggunaan media sosial berpengaruh secara positif dan signifikan terhadap pembelian impulsif. Konformitas berpengaruh positif dan signifikan terhadap pembelian impulsif. Kontrol diri tidak mampu memperlemah pengaruh penggunaan media sosial terhadap pembelian impulsif. Kontrol diri tidak mampu memperlemah pengaruh konformitas terhadap pembelian impulsif. Saran dari penulis yaitu siswa sebaiknya mempunyai perencanaan dan pertimbangan yang matang dalam hal keputusan pembelian.
Penerapan Sistem Informasi Point Of Sale (POS) untuk Menunjang Proses Traksaksi UMKM Toko Broovape Kelurahan Sawah Lebar Baru
Authors: Coastera Funny Farady , Yusa Mochammad , Andreswari Desi
Published: June 2024

Pentingya Pengolahan data di berbagai aspek yang menunjang kebutuhan manusia menandai semakin pesatnya perkembangan Teknologi Informasi (TI). Salah satunya Usaha Masyarakat Kecil/Menengah (UMKM). Di Indonesia, UMKM merupakan salah satu penyumbang devisa negara. BPS menyebutkan bahwa UMKM telah berkontribusi besar terhadap Produk Domestik Bruto (PDB) Indonesia yaitu 61,97% dari total PDB nasional atau setara dengan Rp8.500 triliun di tahun 2021. Salah satu UMKM yang ada di wilayah kelurahan Sawah Lebar Baru adalah BrooVape. Saat ini sistem penjualan masih belum terkomputerisasi semua, pada saat menghitung barang-pun masih dilakukan tulis tangan. Kemudian proses pengecekan stok barang masih dilakukan secara manual sehingga untuk mengetahui jumlah stok pemilik toko harus melakukan proses pengecekan setiap harinya. Tujuan dari kegiatan ini adalah menerapkan Sistem informasi Point of sale yang dapat menunjang proses bisnis transaksi penjualan pada UMKM. Kegiatan dilakukan melalui tiga tahap kegiatan yaitu pengembangan sistem informasi dan sosialisasi penggunaan sistem informasi serta evaluasi melalui sosialisasi penggunaan sistem informasi.
PENYULUHAN PEMBUATAN TANAMAN HIDROPONIK DI DESA PADANG NIBUNG
Authors: Dhiya Arga Saputra  , Nugroho Setyo Eko Nugroho
Published: June 2024

Pertanian merupakan potensi yang ada di Desa Padang Nibung. Masyarakat di Desa Padang Nibung adalah penduduk usia produktif yang tidak memanfaatkan manajemen waktu secara optimal. Pemberdayaan masyarakat di Desa Padang Nibung Kecamatan Bunga Mas dilatarbelakangi oleh permasalahan penduduk usia kerja yaitu waktu luang yang kurang produktif, rendahnya pemanfaatan pekarangan yang sempit di rumah warga, rendahnya pengetahuan tentang pola tanam hidroponik, dan kurangnya pengetahuan masyarakat tentang organik. produksi pupuk.  Pemberdayaan masyarakat bertujuan untuk meningkatkan keterampilan, pengetahuan dan produktivitas produk hidroponik dan pupuk organik.   Sasaran keluaran dalam kegiatan ini adalah (1) meningkatnya pengetahuan dan keterampilan, kesadaran dan motivasi masyarakat untuk memanfaatkan lahan/pekarangan kosong sebagai sumber ketahanan pangan/pangan; (2) pemasangan teknik hidroponik sederhana dan perawatannya yang dapat diterapkan oleh masyarakat;  dan (3) mampu memproduksi pupuk organik untuk tanaman khususnya   hidroponik   dan   tanaman.   Metode   partisipatif   digunakan   untuk   melibatkan masyarakat secara aktif dalam penerapan teknik hidroponik dan produksi pupuk organik.  Hasil kegiatan yang telah dilakukan antara lain pengenalan cara dan teknik pemasangan hidroponik, pengetahuan alat dan bahan, serta cara pembuatan pupuk organik.   Program kerja kelompok yang telah dilaksanakan membantu masyarakat dalam memecahkan masalah dan meningkatkan produktivitas masyarakat
Pendampingan Edukasi Penyakit Tuberkulosis, Penggunaan Obat TB, Hand Hygiene dan Etika Batuk di Kelurahan Bangetayu Wetan
Authors: Desmiany Duri Iin , Afriansya Roni , Rizal Maulana Mochamad
Published: June 2024

Kegiatan pengabdian kepada masyarakat ini dilaksanakan dengan tujuan untuk membantu memberi pendampingan dan edukasi mengenai pencegahan Penyakit Tuberkulosis (TB) kepada masyarakat Kelurahan Bangetayu Wetan. Hal ini dilakukan karena risiko penyebaran penyakit Tuberkulosis, Penggunaan Obat TB, Hand Hygiene dan Etika Batuk. Tuberculosis merupakan penyakit menular yang menyerang paru-paru dan disebabkan oleh bakteri Mycobacterium tuberculosis. Kegiatan pengabdian masyarakat ini merupakan edukasi dengan pendekatan sosialisasi dan diskusi kepada masyarakat Kelurahan Bangetayu Wetan, Waktu Pelaksanaan 26 Juli 2023. Kegiatan ini memberikan penjelasan kepada masyarakat terkait penyakit tuberkulosis, Penggunaan obat TB, Etika Batuk dan Hand hygiene yang dapat mencegah penularan penyakit tuberkulosis. Hasil ini menunjukkan bahwa edukasi melalui sosialisasi dan diskusi menggunakan metode secara langsung kepada masyarakat efketif meningkatkan pemahaman dan minat masyarakat dalam ikut mencegah penyakit tuberkulosis. Kegiatan pengabdian masyarakat ini diharapkan dapat berkelanjutan sehingga masyarakat dapat mengaplikasikan dalam kehidupan sehari-hari, sehingga derajat kesehatan dan angka Tuberkulosis berkurang.
A COGNITIVE STYLISTIC ANALYSIS OF PINK FLOYD’S SONG LYRIC “TIME”
Authors: Sirait Anjeli Lorena , Siburian Jessica Br. , Sitompul Ines Margaretha , Rangkuti Rahmadsyah
Published: June 2024

The objective of this paper is to describe how the content of song lyrics interacts with concepts of time, memory, and human experience and knowing how language and cognition are interrelated to create profound artistic expression in music through scheme theory, metaphor theory, and figures of speech as features of creativity and novelty in language use. The data was derived from the song entitled Time by Pink Floyd.  The research method used in this study is qualitative descriptive. The result of this study is skillfully employing various figures of speech, such as metaphor, personification, and paradox, to convey the complexities of time, aging, regret, and the human experience. These literary devices engage the listener's intellect and emotions, prompting reflection on the passage of time and its impact on our lives. Furthermore, the song employs schema theory to activate the "Time that has passed" schema in listeners, encouraging them to reflect on the value of time and the importance of seizing precious moments before they slip away. The song's vivid imagery and metaphors serve as a bridge between abstract concepts and concrete experiences, making it a relatable and thought-provoking piece of art.
A CORPUS-BASED STUDY ON ERRORS IN WRITING DESCRIPTIVE TEXT COMMITTED BY SENIOR HIGH SCHOOL STUDENTS IN A MODELLED-SCHOOL CONTEXT WITHIN SIKKA REGENCY, EAST NUSA TENGGARA PROVINCE
Authors: De Rosari Vinsensia Yosefa , Uran Stefanus Igolois Grenga , Balik Lusiyana Marieta
Published: June 2024

This case study aims to identify the types and causes of errors often made by students in writing descriptive texts and to provide solutions to reduce errors in writing. This study employs the five stages of error analysis proposed by Ellis and Barkhuzein. Data were collected through observation, written tests, and interviews and were analyzed using qualitative and quantitative approaches. The corpus under inquiry consisted of 50 students’ descriptive writing texts from two classes. The most identified error was the linguistic errors in writing related to second language usage errors. A lack of vocabulary mastery and L1 interference generally cause errors in writing made by students. After the error evaluation stage, the authors recommend the implementation of Continuous Writing Activities and Process Writing Strategies to help students improve their ability to write in English and reduce the errors they make.
Exploring moral quandaries: An interpretative phenomenological inquiry into the ethical dilemmas faced by Emergency Medical Technicians (EMTs) in the Southern Philippines
Authors: Guro Raifa M. , Ali Asnorah P. Hadji , Bangcola Ashley A. , Macawadib Monalinda M. , Ali Norhanie A. , Macalnas Alibasher D.
Published: June 2024

Background: Emergency Medical Technicians (EMTs) in Lanao del Sur, Philippines, face ethical dilemmas shaped by the Meranao cultural value of ‘Maratabat,’ which emphasizes family honor and dignity. Understanding these cultural nuances is crucial for improving emergency medical care and addressing the ethical challenges encountered by EMTs in this region.
Objective: This study aimed to explore the ethical dilemmas experienced by EMTs in disaster management settings, particularly how cultural values shape their decision-making processes.
Methods: A phenomenological design was utilized. Eight EMTs working at the Provincial Disaster Risk Reduction and Management Office (PDRRMO) of Lanao del Sur, Philippines, were purposefully selected to participate. Data were collected from 31 January 2024 to 1 February 2024 through in-depth interviews, and thematic analysis was employed for data analysis.
Results: Key themes emerged, including navigating complex dilemmas, adhering to organizational protocols, influential factors impacting EMTs’ capacity to handle ethical dilemmas in emergency services, and coping strategies for EMTs in addressing the psychological burden from ethical dilemmas in emergency care. The concept of ‘Maratabat’ greatly affects EMTs’ ethical decision-making processes, guiding their actions in the field.
Conclusion: The study highlights the importance of cultural values, organizational backing, and coping mechanisms in effectively enabling EMTs to address moral quandaries in their professional roles. Institutional support, a positive organizational culture, and continuous education are essential in assisting EMTs in making informed decisions amid ethical dilemmas. These findings have implications for interventions and strategies to support EMTs as frontline providers of emergency medical services, enhancing patient care quality during crises.
A systematic review of empirical studies incorporating English movies as pedagogic aids in English language classroom
Authors: Pavithra K. , Gandhimathi S. N. S.
Published: June 2024

The use of movie as an audio-visual multimodal tool has been extensively researched, and the studies prove that they play a vital role in enhancing communicative competence. Incorporating authentic materials like movies, television series, podcasts, social media, etc., into language learning serves as a valuable resource for the learners, for it exposes them to both official and vernacular language. The current study aims to systematically analyze the preceding studies that conjoined English movies into the curriculum to teach English. It also examines and evaluates the empirical research that various researchers conducted from 2000 to 2023. The articles were primarily sourced from prominent academic databases such as ProQuest, ScienceDirect, Scopus, Web of Science, and Google Scholar. Inclusion and exclusion criteria were applied in screening the 921 sources, of which 23 empirical studies were eligible for the review as a result of a three-stage data extraction process as shown in the “Preferred Reporting Items for Systematic Reviews and Meta Analyses” (PRISMA) chart. The extraction of data from the review encompasses an overview of the empirical studies, methodologies, participants, and interventions. The extracts were systematically analyzed using the software’s End Note and Covidence. The analysis of the existing literature and experimental data substantiates that teaching and learning English as a second or foreign language using movies as teaching aids exhibit promising prospects for enhancing English language proficiency. The findings of the study reveal different genres of movies that aid the facilitator in producing effective instruction materials with clearly defined objectives and guided activities. It is also observed that the learners have a positive experience with long-term learning benefits.
Cathepsin S (CTSS) in IgA nephropathy: an exploratory study on its role as a potential diagnostic biomarker and therapeutic target
Authors: Fu Shaojie , Wu Meiyan , Cheng Yanli , Guan Yan , Yu Jinyu , Wang Xueyao , Su Sensen , Wu Hao , Ma Fuzhe , Zou Yan , Wu Shan , Xu Hongzhao , Xu Zhonggao
Published: June 2024

Introduction

IgA nephropathy (IgAN), a prevalent form of glomerulonephritis globally, exhibits complex pathogenesis. Cathepsins, cysteine proteases within lysosomes, are implicated in various physiological and pathological processes, including renal conditions. Prior observational studies have suggested a potential link between cathepsins and IgAN, yet the precise causal relationship remains unclear.

Methods

We conducted a comprehensive bidirectional and multivariable Mendelian randomization (MR) study using publicly available genetic data to explore the causal association between cathepsins and IgAN systematically. Additionally, immunohistochemical (IHC) staining and enzyme-linked immunosorbent assay (ELISA) were employed to evaluate cathepsin expression levels in renal tissues and serum of IgAN patients. We investigated the underlying mechanisms via gene set variation analysis (GSVA), gene set enrichment analysis (GSEA), and immune cell infiltration analysis. Molecular docking and virtual screening were also performed to identify potential drug candidates through drug repositioning.

Results

Univariate MR analyses demonstrated a significant link between increased cathepsin S (CTSS) levels and a heightened risk of IgAN. This was evidenced by an odds ratio (OR) of 1.041 (95% CI=1.009–1.073, P=0.012) as estimated using the inverse variance weighting (IVW) method. In multivariable MR analysis, even after adjusting for other cathepsins, elevated CTSS levels continued to show a strong correlation with an increased risk of IgAN (IVW P=0.020, OR=1.037, 95% CI=1.006–1.069). However, reverse MR analyses did not establish a causal relationship between IgAN and various cathepsins. IHC and ELISA findings revealed significant overexpression of CTSS in both renal tissues and serum of IgAN patients compared to controls, and this high expression was unique to IgAN compared with several other primary kidney diseases such as membranous nephropathy, minimal change disease and focal segmental glomerulosclerosis. Investigations into immune cell infiltration, GSEA, and GSVA highlighted the role of CTSS expression in the immune dysregulation observed in IgAN. Molecular docking and virtual screening pinpointed Camostat mesylate, c-Kit-IN-1, and Mocetinostat as the top drug candidates for targeting CTSS.

Conclusion

Elevated CTSS levels are associated with an increased risk of IgAN, and this enzyme is notably overexpressed in IgAN patients’ serum and renal tissues. CTSS could potentially act as a diagnostic biomarker, providing new avenues for diagnosing and treating IgAN.
Are peptidomimetics the compounds of choice for developing new modulators of the JAK-STAT pathway?
Authors: Cugudda Alessia , La Manna Sara , Marasco Daniela
Published: June 2024

Protein-protein interactions (PPIs) play critical roles in a wide range of biological processes including the dysregulation of cellular pathways leading to the loss of cell function, which in turn leads to diseases. The dysfunction of several signaling pathways is linked to the insurgence of pathological processes such as inflammation, cancer development and neurodegeneration. Thus, there is an urgent need for novel chemical modulators of dysregulated PPIs to drive progress in targeted therapies. Several PPIs have been targeted by bioactive compounds, and, often, to properly cover interacting protein regions and improve the biological activities of modulators, a particular focus concerns the employment of macrocycles as proteomimetics. Indeed, for their physicochemical properties, they occupy an intermediate space between small organic molecules and macromolecular proteins and are prominent in the drug discovery process. Peptide macrocycles can modulate fundamental biological mechanisms and here we will focus on peptidomimetics active on the Janus kinase/signal transducers and activators of transcription (JAK-STAT) pathways.
The role of platelet desialylation as a biomarker in primary immune thrombocytopenia: mechanisms and therapeutic perspectives
Authors: Zhang Qianhui , Huang Miao , Thomas Elizabeth Rosalind , Wang Lu , Liu Jia , Li Xiang , Luo Jiesi , Zou Wenjun , Wu Jianming
Published: June 2024

Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by the destruction of platelets. Although it was long believed that the critical role of autoantibodies in platelet destruction, primarily through the Fc-dependent platelet clearance pathway, recent findings indicate that the significance of the Fc-independent platelet clearance pathway mediated by hepatocytes, thus shedding light on a previously obscure aspect of ITP pathogenesis. Within this context, the desialylation of platelets has emerged as a pivotal biochemical marker. Consequently, targeting platelet desialylation emerges as a novel therapeutic strategy in the pathogenesis of ITP. Notably, prevailing research has largely focused on antiplatelet antibodies and the glycosylation-associated mechanisms of platelet clearance, while comprehensive analysis of platelet desialylation remains scant. In response, we retrospectively discuss the historical progression, inducing factors, generation process, and molecular regulatory mechanisms underlying platelet desialylation in ITP pathogenesis. By systematically evaluating the most recent research findings, we contribute to a comprehensive understanding of the intricate processes involved. Moreover, our manuscript delves into the potential application of desialylation regulatory strategies in ITP therapy, heralding novel therapeutic avenues. In conclusion, this manuscript not only fills a critical void in existing literature but also paves the way for future research by establishing a systematic theoretical framework. By inspiring new research ideas and offering insights into the development of new therapeutic strategies and targeted drugs, our study is poised to significantly advance the clinical management of ITP.