bluuebunny/crossref_metadata_2025 huggingface dataset:
Kontinuität im Neubeginn
Authors: Nicolaysen Rainer , Fegebank Katharina , Rupp Susanne , Guhl Anton F.
Published: July 2023

Nach der kampflosen Besetzung Hamburgs durch britische Truppen am 3. Mai 1945 wurde die Hamburger Universität geschlossen, aber bereits am 6. November 1945 – ein halbes Jahr nach Ende des „Dritten Reichs“ und des Zweiten Weltkriegs – mit einem Festakt in der Musikhalle wiedereröffnet. Den 70. Jahrestag dieser Wiedereröffnung am 6. November 2015 nahm die Universität Hamburg zum Anlass, sich erneut öffentlich mit dem schwierigen Übergang der eigenen Institution von der NS-Diktatur in die demokratische Nachkriegszeit auseinanderzusetzen. Dieser Band der „Hamburger Universitätsreden“ dokumentiert die vier am 6. November 2015 im Magdalene-Schoch-Hörsaal im Hauptgebäude der Universität gehaltenen Reden.
Women Entrepreneurship Comparative Study in Service Sector
Authors: Manikyam G.M.
Published: July 2023

Service sector is an easily approachable sector for entrepreneurship for low investment, easy made infrastructure and its nature. Especially, it is an added advantage for women because they have more patience, creativity, hospitality and etc. developing countries like India have all facilities to support entrepreneurship, especially in the service sector. In the present paper an attempt has been made to analyze the problems of women entrepreneurs in service sector in rural and urban the prospects of women entrepreneurship. In order to develop a business, women entrepreneurs need to possess a lot of characteristics. Despite having those characteristics, women face a lot of problems and challenges pertaining to business and work-life balance. The crucial challenges and problems faced by women in leading their venture are identified in this research. If a woman is vibrant enough to start her enterprise, she has to understand that the abovementioned problems and challenges may be a hindrance and make her face failure in her business. Hence, she has to prepare herself to face the above challenges and issues in order to grow and sustain her venture
Quality Assessment of modelled protein structure using Back-propagation and Radial Basis Function algorithm
Authors: Dr. Baljit Singh Khehra Er. Amanpreet Kaur,
Published: July 2023

Protein structure prediction (PSP) is the most important and challenging problem in bioinformatics today. This is due to the fact that the biological function of the protein is determined by its structure. While there is a gap between the number of known protein structures and the number of known protein sequences, protein structure prediction aims at reducing this structure –sequence gap. Protein structure can be experimentally determined using either X-ray crystallography or Nuclear Magnetic Resonance (NMR). However, these empirical techniques are very time consuming. So, various machine learning approaches have been developed for protein structure prediction like HMM, SVM and NN. In this paper, general introductory background to the area is discussed and two approaches of neural network i.e backpropagation and radial basis function are used for the prediction of protein tertiary structure. The aim of the study is to observe performance and applicability of these two neural network approaches on the same problem. More specifically, feed-forward artificial neural networks are trained with backpropagation neural network and radial basis function neural networks. These algorithms are used for the classification of protein data set, trained with the same input parameters and output data so that they can be compared. The advantages and disadvantages, in terms of the quality of the results, computational cost and time are identified. An algorithm for the selection of the spread constant is applied and tests are performed for the determination of the neural network with the best performance. These approaches depends on the chemical and physical properties of the constituent amino acids. Not all neural network algorithms have the same performance, so we represent the general success keys for any such algorithm. The data set used in the study is available as supplement at http://bit.ly/RF-PCP-DataSets.
Design Defects and Quality of Government Funded Building Projects In Isiolo County, Kenya
Authors: Dr. Cavens Kithinji Mbijiwe Lawrence Kinyua, Kiarie Antony Kimemia,
Published: July 2023

The Interface between design and pre-construction of government funded buildings projects is pivotal and yet very complicated. It is at this interface that defects emanating from design errors in the buildings have been found to occur adversely influencing the realization of quality buildings. This study investigated the influence of design defects on the quality of government funded building projects in Isiolo County. The study is guided by one theory; The Bad Apple Theory of human error. Descriptive survey research design is adopted. Study’s target population consisted; 137project clients, 92 contractors and 16 consultants. 149 respondents made up the study’s sample size and final subjects selected using Stratified and Simple random sampling techniques. Primary data was collected using three questionnaires. The analysis of quantitative data was achieved making use of descriptive statistics and qualitative data on the other hand was reported in form of narratives pivoted on themes under study. The study established that poor functionality of building parts, buildings’ fragility, high occurrence of unpleasant aesthetics in buildings and cost overruns were all as a result of design defects. This study concluded that design defects to a great extent influenced the quality of government funded building projects in Isiolo County. The study recommends that a design review involving project clients and consultants prior to the approval of the final design for construction should beunder taken. Further, to address design defects architectures should provide clear graphic and written representations which will allow contractors to transform concepts into physical reality in execution of government funded building projects in Is iolo County.
Purification and characterization of thermo alkaliphilic catalase from haloarchaeal strain
Authors: Stevens Jones R.D Murugan S Asha K. R. T
Published: July 2023

In this study, Haloarchaeal strain was isolated from water samples collected from salt pan. The strain was further treated with 2% H2O2 and incubated in a water bath with shaker for 12 days. Supernatant was collected from early log phase and was used as enzyme source. Protein was precipitated by ice cold ethanol followed by purification with Sephadex G-150 column chromatography. SDS-PAGE report showed that that the molecular weight of catalase was found to be 111.2 KD using 12% gel. The results showed that the optimum pH of catalase in supernatant was found to be at 9.0 and optimum temperature was found to be at 65 °C. In case of purified sample the activity of catalase was found to be increased at pH 10 and optimum temperature was noticed at 65ºC. Activity of enzyme was increased in increasing concentration of enzyme upto 2.5ml, beyond that the activity declined. The enzyme has great affinity for the substrate H2O2and the Vmax and Km was calculated as 80mM and 40mM respectively by Michaelis menton plot. The activity of catalase from purified sample was also assayed in the presence of metal ions and the results obtained indicated that the activity was found to be increased significantly from 85.5 mM/mL and the activity was stable and constant up to 171 mM/mL of NaCl and at 0.024mM/mL of MgSO4 and 0.03mM/mL of MnSO4. The activity was found to be decreased when the concentration of ZnSO4 was increased. Keywords: Halobacterium, Catalase, Zobell marine agar, SDS-PAGE
Teaching Materials Developments for Digital Native Students
Authors: Muzaki Ferril Irham
Published: July 2023

The total quality management had raised the further question about changing in classroom activities. TheFurther development this idea will determine that human factors take role in total quality management,especially in developing classroom presentation. Thus, this research report is purposed to explain howclassroom management influences the students' behavior in class. Thus, the classroom presentation willmore applicable for students, also make the warm discussion, as the total quality management is used inclassroom activities. The students have to be active when they are learning in class
A strategic Vision to Develop Research Performance Based on the Transition to a Research University
Authors: Tanira Mohammed O. , KhalfAlla Mahmoud E.
Published: July 2023

This study aimed at suggesting a strategic vision to develop research performance at the Palestinian universities in the light of requirements for transition to a research university. Researchers used the mixed method. Quantitative data were collected by using a questionnaire that was applied to (339) university instructors and the qualitative data were collected from three focus groups. The study concluded that the estimations of the study participants on the real research performance at the Palestinian universities were of a relative weight (55.28%). Based on the results, the researchers structured a matrix for strategic analysis and a suggested strategic vision that were presented to a focus group of experts (No=7) in educational administration and scientific research to control it. The study recommended the necessity to adopt the strategic vision suggested by the Palestinian Ministry of Higher Education and Universities, in addition to the adoption of publicized scientific and administrative policies to support the development of the Palestinian universities and the transformation from traditional universities to research universities.
Design of a Samier Cracker Dough Molding Machine Semi-Automatic with Roll Cutting Method
Authors: Prasetiyo Abdul Aziz , Akbar Ali , Tjahjanti Prantasi Harmi
Published: July 2023

The main obstacle that UMKM SA has is limited production technology which is still manual so that workers take a long time and production results are not good because the thickness of the crackers is uneven and the sizes cannot match. So it is necessary to design a cracker-making machine by making a printing roll tool. The design method uses the manufacturing process method which is based on the cutting process and has a different perspective from the previous thing. Where the researcher analyzes the advantages and disadvantages of the product to be made, has an overview of the product to be made by taking samples of material sources and data from the analysis that has been carried out directly to the resource persons as well as by analyzing the processes that have been carried out. The results of the study are from data analysis of the cracker dough cutting machine with the selected concept, it can be said to be effective with a faster time record in each test, good efficiency and effectiveness of the first tool requires an average time of 03:80 to 01:12 with cracker dough size 46x46x1 totaling 121 pieces.
The relationship between polymorphism of IGF2BP2 gene rs4402960 and risk of pan-cancer: a meta-analysis and a bioinformatics analysis
Authors: lu fengke , Zhang Hongyu , Zhang Wei
Published: July 2023

Background
Although some studies have established the relationship between insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs4402960 polymorphism and the pathogenesis of cancer. But the results are contradictory. We conducted a meta-analysis to assess the relationship between IGF2BP2 gene polymorphism and cancer risk. Furthermore, the expression of IGF2BP2 in pan-cancer tissues and normal tissues was further analyzed from the perspective of bioinformatics analysis.
Methods
Using published case–control studies up to August 15, 2021, the literature search included searches of PubMed, Web of Science, and EMBASE to determine the samples that met the inclusion criteria. The heterogeneity test was used in five genetic models. Odds ratios (OR), 95% confidence intervals (CI), and p-values were used to evaluate the combined effects of various genetic models. Sensitivity analysis and publication bias were also performed. Transcriptomic information on IGF2BP2 and corresponding clinical information was downloaded from the TCGA and GTEx databases. Differences in IGF2BP2 expression between various kinds of cancer tissues and normal tissues were analysed.
Results
This meta-analysis contained 6 case–control studies, with 5,908 cases and 7,890 controls. There was only an association between IGF2BP2 rs4402960 polymorphism and cancer risk in the heterozygous genetic model (heterozygous: OR = 1.080, 95% CI = 1.003–1.163, p = 0.041). The sensitivity analysis examined the effect of various research studies on the combined OR by deleting one study by turns. No publication bias was found in the genetic models. We found that IGF2BP2 was over-expressed in breast cancer, non-small cell lung cancer, colorectal cancer and esophageal cancer (P < 0.001).
Conclusions
The results of meta-analysis showed that IGF2BP2 gene polymorphism may be related to cancer risk. IGF2BP2 was over-expressed in Breastcancer, Non-small Cell Lung Cancer, Colorectal Cancer, Breast cancer and esophageal cancer tissues. IGF2BP2 may be used as an index of early cancer screening and prognosis treatment.
PENGARUH KARAKTERISTIK TUJUAN ANGGARAN TERHADAP KINERJA APARAT PEMERINTAH DAERAH DI PROVINSI JAMBI (STUDI PADA DINAS – DINAS DI PROVINSI JAMBI)
Authors: Ramadani Yolanda , Rahayu Sri , Gowon Muhammad
Published: July 2023

Penelitian ini bertujuan untuk memberikan bukti empiris pengaruh Partisipasi anggaran, kejelasan tujuan anggaran, evaluasi anggaran, umpan balik anggaran, kesulitan tujuan anggaran secara simultan berpengaruh terhadap kinerja aparat pemerintah daerah. Populasi dalam penelitian ini adalah Organisasi Perangkat Daerah – Dinas yang berjumlah 18 dinas di Provinsi Jambi. Penelitian ini menggunakan metode sampel jenuh. Sampel penelitian ini Kepala Dinas, Sekretaris, Kasubag Umum dan Kepegawaian, Kasubag Keuangan dan Aset, Kasubag Perencanaan dan Evaluasi, Kabid didasari atas asumsi bahwa responden inilah yang melakukan dan terlibat langsung secara teknis dalam hal penyusunan anggaran. Pengumpulan data penelitian dilakukan dengan menyebarkan kuesioner kepada 108 responden. Pengolahan data menggunakan software SPSS 22.0. Alat analisis dalam penelitian ini adalah analisis regresi linear berganda. Hasil penelitian menemukan bahwa secara simultan partisipasi anggaran, kejelasan tujuan anggaran, evaluasi anggaran, umpan balik anggaran, dan kesulitan tujuan anggaran berpengaruh terhadap kinerja aparat pemerintah daerah. Secara parsial, partisipasi anggaran, kejelasan tujuan anggaran, umpan balik anggaran, dan kesulitan tujuan anggaran berpengaruh terhadap kinerja aparat pemerintah daerah, tetapi evaluasi anggaran tidak berpengaruh terhadap kinerja aparat pemerintah daerah.
PENGARUH KEMAMPUAN INFORMASI LABA, FREE CASH FLOW, BEBAN DEPRESIASI, DAN RASIO PERPUTARAN PIUTANG DALAM MEMPREDIKSI ARUS KAS DI MASA DEPAN (STUDI EMPIRIS PADA PERUSAHAAN REAL ESTATE DAN PROPERTY YANG TERDAFTAR DI BURSA EFEK INDONESIA PERIODE 2015-2018)
Authors: Afrizela Nico , Afrizal Afrizal , Kusumastuti Ratih
Published: July 2023

Penelitian ini bertujuan untuk memberikan bukti empiris mengenai pengaruh kemampuan informasi laba, free cash flow, beban depresiasi, dan rasio perputaran piutang  dalam memprediksi arus kas di masa depan pada perusahaan real estate dan property yang terdaftar di Bursa Efek Indonesia periode 2015-2018. Teori yang digunakan dalam penelitian ini adalah teori sinyal atau signalling theory. Populasi dalam penelitian ini terdiri dari 61 perusahaan real estate dan property yang terdaftar di Bursa Efek Indonesia. Teknik pengambilan sampel dalam penelitian ini adalah purposive sampling. Sehingga diperoleh sampel yang digunakan sebanyak 23 perusahaan. Jenis data yang digunakan adalah data sekunder. Analisis data yang dilakukan menggunakan analisis regresi linear berganda dimana dilakukan uji asumsi klasik terlebih dahulu sebelum pengujian hipotesis menggunakan uji-f, uji-t dan koefisien determinasi. Hasil penelitian menunjukkan bahwa berdasarkan hasil uji-f untuk informasi laba, free cash flow, beban depresiasi, dan rasio perputaran piutang secara simultan atau bersama-sama berpengaruh signifikan positif dalam memprediksi arus kas di masa depan pada perusahaan real estate dan property yang terdaftar di Bursa Efek Indonesia tahun 2015-2018. Berdasarkan hasil uji-t menunjukkan bahwa variabel informasi laba, beban depresiasi, dan rasio perputaran piutang secara parsial berpengaruh signifikan positif sedangkan variabel free cash flow secara parsial berpengaruh signifikan negatif dalam memprediksi arus kas di masa depan pada perusahaan real estate dan property yang terdaftar di Bursa Efek Indonesia tahun 2015-2018.
PENGARUH PEMBAYARAN DIVIDEN TUNAI DAN LEVERAGE TERHADAP KUALITAS LABA (STUDI EMPIRIS PADA PERUSAHAAN INFRASTRUCTURE, UTILITIES, AND TRANSPORTATION YANG TERDAFTAR DI BURSA EFEK INDONESIA PERIODE TAHUN 2016-2019)
Authors: H Widya Riri , Fitriyani Dewi , Yustien Reni
Published: July 2023

Penelitian ini bertujuan untuk menguji pengaruh pembayaran dividen tunai dan   leverage terhadap kualitas laba pada perusahaan infrastructure, utilities and transportation yang terdaftar di BEI. Penelitian ini menggunakan sampel perusahaan infrastructure, utilities and transportation yang terdaftar di BEI selama tahun 2016 – 2019. Sampel penelitian diperoleh dengan metode purposive sampling. Sampel yang digunakan sebanyak 33 perusahaan. Teknik analisis data yang digunakan adalah statistic deskriptif, uji asumsi klasik, dan analisis regresi berganda. Hasil pengujian hipotesis menunjukkan bahwa secara simultan dan parsial pembayaran dividen tunai dan leverage berpengaruh terhadap kualitas laba pada perusahaan infrastructure, utilities and transportation yang terdaftar di BEI.
ANALISIS FINANCIAL DISTRESS DENGAN MENGGUNAKAN METODE ALTMAN Z-SCORE DAN SPRINGGATE UNTUK MEMPREDIKSI KEBANGKRUTAN PADA PERUSAHAAN JASA KEUANGAN DAN ASURANSI (STUDI EMPIRIS PADA PERUSAHAAN DI BUMN TAHUN 2014 - 2016)
Authors: Eka Yosi , Diah P.A Enggar , Herawaty Netty
Published: July 2023

Penelitian ini berjudul analisis financial distress dengan menggunakan metode Altman Z Score dan Springgate untuk memprediksi kebangkrutan pada perusahaan jasa keuangan dan asurangsi (studi empiris pada perusahaan di BUMN tahun 2014-2016). Tujuan penelitian untuk mengukur potensi financial distress perusahaan BUMN di Indonesia dengan menggunakan model Altman Z Score dan Springgate serta untuk melihat perbedaan penilaian potensi financial distress dengan menggunkan model Altman Z Score dan Springgate. Populasi dalam penelitian ini adalah perusahaan Jasa keuangan dan asuransi yang terdaftar di BUMN pada tahun 2014-2016. Metode pengambilan sampel yang digunakan adalah purposive sampling dengan jumlah sampel 10 perusahaan. Metode analisis yang digunakan dalam penelitian ini adalah uji beda wicoxon dengan menggunakan software SPSS. Hasil penelitian ini menyimpulkan bahwa (1) berdasarkan penilaian potensi financial distress model Altman Z Score pada perusahaan BUMN periode 2014-2016 bahwa perusahaan berada dalam kondisi keuangan yang tidak bangkrut (2) berdasarkan penilaian potensi financial distress model Springate pada perusahaan BUMN periode 2014-2016 bahwa perusahaan berada dalam kondisi keuangan yang bangkrut (3) Berdasarkan hasil uji Wilcoxon menyatakan bahwa terdapat perbedaan penilaian potensi financial distress pada perusahaan BUMN dengan menggunakan model Altman Z Score dan Springate.
STUDY OF ENTREPRENEURSHIP ORIENTATION AND SELF-EFFICACY ON ENTREPRENEURSHIP SUCCESS AND MODERATION OF ENVIRONMENTAL INSTABILITY IN COVID 19 PANDEMIC CONDITIONS
Authors: Muhammad Fadhli
Published: July 2023

This study aims to analyze entrepreneurial orientation and self-efficacy on entrepreneurial success moderating environmental instability with entrepreneurial orientation on entrepreneurial success. This study used a descriptive quantitative method. The research was conducted in February-May 2022 in Surakarta. The population in this study were Micro Small and Medium Enterprises (MSME) actors spread in Surakarta with a total sample of 169 respondents using a simple census sampling technique based on representation of several types of MSME. The data collection technique was carried out by means of a questionnaire/questionnaire. Testing the hypothesis used the regression test and moderation regression test with SPSS software version 26.0. The results of the study conclude that entrepreneurial orientation influences entrepreneurial success. Entrepreneurial self-efficacy influences entrepreneurial success. Moderation of environmental instability on the effect of entrepreneurial orientation on entrepreneurial success is not able to moderate. The environmental instability variable is able to moderate the effect of entrepreneurial self-efficacy on entrepreneurial success.
Community analysis of large-scale molecular dynamics simulations elucidated dynamics-driven allostery in Tyrosine kinase 2
Authors: Vlassi Metaxia , Lesgidou Nastazia
Published: July 2023

TYK2 is a non-receptor tyrosine kinase, member of the Janus kinases
(JAK), with a central role in several diseases, including cancer. The
JAKs’ catalytic domains (KD) are highly conserved, yet the isolated
TYK2-KD exhibits unique specificities. In a previous work, using
molecular dynamics (MD) simulations of a catalytically-impaired TYK2-KD
variant (P1104A) we found that this amino-acid change of its
JAK-characteristic insert (αFG), acts at the dynamics level. Given that
structural dynamics is key to allosteric activation of protein kinases,
in this study we applied a long-scale MD simulation and investigated an
active TYK2-KD form in the presence of adenosine 5’-triphosphate and one
magnesium ion that represents a dynamic and crucial step of the
catalytic cycle, in other protein kinases. Community analysis of the MD
trajectory shed light, for the first time, on the dynamic profile and
dynamics-driven allosteric communications within the TYK2-KD during
activation and revealed that αFG and amino-acids P1104, P1105 and I1112
in particular, hold a pivotal role and act synergistically with a
dynamically coupled communication network of amino-acids serving
intra-KD signaling for allosteric regulation of TYK2 activity.
Corroborating our findings, most of the identified amino-acids are
associated with cancer-related missense/splice-site mutations of the
Tyk2 gene. We propose that the conformational dynamics at this
step of the catalytic cycle, coordinated by αFG, underlies TYK2-unique
substrate recognition and accounts for its distinct specificity. In
total, this work adds to knowledge towards an in-depth understanding of
TYK2 activation and may be valuable towards a rational design of
allosteric TYK2-specific inhibitors.
Carbon Pricing and Fossil Fuel Subsidy Rationalization Tool Kit
Authors: Jonassen Rachael , Skou Andersen Mikael , Cottrell Jacqueline , Bhattacharya Sandeep
Published: July 2023

This tool kit offers a step-by-step guide for economies in Asia and the Pacific looking to design, build, and implement emission trading systems (ETS) to help speed up their transition to a greener, more inclusive future. Using case studies to illustrate best practices and lessons learned by countries including Viet Nam and India, it explains the need to design robust legal frameworks before setting up ETSs. It outlines carbon taxes, analyzes fossil fuel subsidy rationalization, and shows why securing support from stakeholders is key for countries planning to implement ETS programs to help meet their climate targets.
Academic Stress in the Final-Year Students: Do Religiosity and Religious Coping Matter?
Authors: Eko Sujadi
Published: July 2023

Final-year students are often faced with stressful conditions. They have to complete all the academic demands that are so many. This study aimed to examine the direct effect of religiosity and religious coping on academic stress and the mediating effect of religious coping on the relationship between religiosity and academic stress. A total of 191 final-year students at one of the universities in Indonesia participated in filling out the College Student Stress Scale, Religiosity Scale among Muslims and The Brief RCOPE. Structural model testing using the structural equation model through the SmartPLS 3.0. The results showed a direct negative effect of religiosity and religious coping on academic stress. In addition, the relationship between religiosity and academic stress is mediated by religious coping. There needs to be an effort to maximize the process of academic guidance carried out by academic supervisors. Prevention and intervention of academic stress can also be done through guidance and counselling services carried out by professional counsellors. Final-year students also need social support from those closest to them.
COMBATING THE ANTIMICROBIAL RESISTANCE BY PERSONALIZED MEDICINE: A MINI-REVIEW
Authors: Verma Shrikant , Verma Sushma , Abbas Mohammad , Mahdi Farzana
Published: July 2023

The emergence of drug-resistant microorganisms has resulted in the reduced effectiveness of traditional antimicrobial therapies. The World Health Organization (WHO) has recognized antimicrobial resistance (AMR) in bacterial infections as a significant global health crisis. If effective measures are not established by 2050, it is projected that annual deaths from diseases caused by drug-resistant bacteria could reach up to 10 million people. Antimicrobial resistance (AMR) arises due to the transfer of bacteria and genes among humans, animals, and the environment. While there are inherent barriers that impede the unrestricted movement of bacteria and genes, the acquisition of new resistance factors from various species is a common occurrence. This phenomenon undermines our capacity to effectively prevent and treat bacterial infections, posing significant challenges. The core of the problem lies in the evolution of pathogens, which enables bacteria to rapidly adapt to the selective pressures imposed by the use of antimicrobials in medical and agricultural settings. This adaptation encourages the spread of resistance genes or alleles within bacterial populations. To combat these challenges, there is a growing focus on the development of precision antimicrobial treatments that target the key virulence characteristics of individual infections. This approach aims to tailor treatment to specific infections, considering their unique characteristics. In this article, we explore the benefits, advancements, and challenges associated with the development of precision antimicrobial medicines. The goal is to enhance our ability to effectively combat drug-resistant bacteria and mitigate the impact ofAMR on global health.
Assessment of level IIB lymph nodes in oral cancer - Should we spare or care?
Authors: Shanmugam Subbiah , Susikar Sujay , Victor Jebasingh Arun
Published: July 2023

Objectives

The extent of neck dissection over the years has evolved from a radical neck dissection to a super-selective neck dissection with an attempt to achieve a balance between oncological safety and acceptable morbidity. There is an ongoing debate concerning dissection of level IIB in both node negative and positive patients, primarily due to the low incidence of metastasis in this region and possible spinal accessory nerve injury. In this study, we intended to find the rate of metastasis to level IIB nodes in patients who were treated with neck dissection for oral cancers.

Material and Methods

Patients with squamous cell carcinoma of the oral cavity who underwent neck dissection were analyzed. Patients with clinically node negative (cN0) disease underwent selective neck dissection (SND), whereas patients with clinically node positive (cN+) disease underwent modified radical neck dissection (MRND).

Results

Out of the total 34 patients, 12 patients underwent MRND and 22 patients underwent SND. In the MRND group, three patients (25%) had positive level IIB nodes. The median number of IIB nodes removed was two and the median number of positive IIB nodes was one. In the SND group, the median number of IIB nodes removed was three and none of the patients had positive level IIB node.

Conclusion

In oral cancer with cN+, routine dissection of level IIB nodes has both therapeutic and prognostic values. Whereas, in patients with cN0, routine dissection of level IIB nodes can be omitted. Further large volume studies are needed on cN0 disease.
Improving the Ability to Recognize Number Concepts through Number Card Media in Children Aged 4-5 Years
Authors: Mortisari Yuni , Syukri M , Amali Annisa
Published: July 2023

This study aims to investigate the improvement in number concept recognition ability using number cards in 4–5-year-old children in kindergarten. In this study, the action method was used. This form of study is a collaborative study of classroom activities. The study subjects were one teacher and 15 children aged 4 to 5. The data collection methods of this study are observation, interview, and documentation. This study was conducted in two cycles, each cycle consisted of two meetings, and each cycle consisted of four stages: planning, execution, observation, and reflection. The results of this study indicated that learning to recognize the concept of numbers through the media of number cards in children aged 4-5 years at Kindergarten has increased. According to the study results, the child's ability to recognize the numbers 1 to 10 symbols increased with each cycle. Based on the data of this study, the child's number concept recognition ability using number card carriers increased by 18.2% in cycle I and cycle II, while second meeting out of 33% in cycle I and cycle II. It increased by 3% per period. It indicates that 4-5-year-old children in kindergarten can develop their ability to recognize numbers through playing number cards. Keywords: Number Card Media, Kindergarten, Ability to Recognize Number
OVERVIEW OF OCCUPATIONAL HEALTH AND SAFETY IN TRANSPORTATION ACTIVITIES PT ANTAM (PT MEG CONTRACTOR PT ANTAM)
Authors: Manurung Amos Parulian , Meilasari Fitriana , Azwa Nirmala , Sutrisno Hendri , Soeryamassoeka Stefanus Barlian
Published: July 2023

Occupational safety and health aim to create a safe and comfortable environment in carrying out activities or work. In PT ANTAM's bauxite transportation activities, there are still occupational safety and health risks. The purpose of this study was to determine the frequency rate, accident severity (Severity Rate), and Safe T Score in PT ANTAM's bauxite transportation activities. The research method used is a descriptive method, which is a research method that describes quantitative data according to the conditions in the field of bauxite transportation activities. The results of the study are (1) The results of the calculation of the frequency rate of 0 which indicate that there were no mining accidents in bauxite transportation activities in January-September 2019; (2) The result of the calculation of the severity rate (Severity Rate) of the accident is 0 which indicates the absence of the severity of the mining accidents that resulted in that month due to the absence of mining accidents that occurred in that month; (3) The results of the calculation of the safe T-score of 0 indicate the work accident control program does not show a significant change.
SLOPE STABILITY TECHNICAL STUDY USING SLOPE MASS RATING (SMR) METHOD AT PT. KARYA SUMBER ALAM PERKASA, SANGGAU REGENCY, KALIMANTAN BARAT
Authors: Wildani Elgi , Meilasari Fitriana , Purwoko Budhi , Sutrisno Hendri , Syahrudin Syahrudin
Published: July 2023

Soil (topsoil and overburden) above the granite quarry in pit 2 (two) PT. Karya Sumber Alam Perkasa has experienced a landslide. It is probably caused by the condition of pit 2 (two) slopes at PT. Karya Sumber Alam Perkasa, which is currently being mined, is quite steep. External factors that can trigger the movement of rock masses are vibrations due to breakers. This condition has the potential to increase the risk of slope stability. Slope stability is influenced by geological conditions, joints, slope geometry, water conditions below the soil surface, physical and mechanical properties, and vibrations due to blasting and mechanical equipment. Therefore, it is necessary to conduct a technical study of slope stability. The research aims to study rock mass class, potential type of landslide, and potential slope stability. The technical study of slope stability uses the Slope Mass Rating (SMR) method. Data processing using software Rocscience Dips 7.016. Analysis of potential types of landslides based on stereographic projections. The result of the RMR calculation is 78, so the rock mass class is number II, which is included in the excellent category. The results analysis of the potential for the type of failure indicates t tends to lead to the toppling failure, but after the study, there is no failure because it does not meet the landslide requirements. The result of the analysis of potential slope stability is that the slope in pit 2 (two) is safe or stable because the SMR value is 78 and the safety factor value is 2,458.
ENVIRONMENTAL FRIENDLY FIELD TOURISM MANAGEMENT FROM THE PERCEPTION AND EMPOWERMENT OF FARMERS AND LAND OWNERS IN PUNGGUR KECIL VILLAGE, KUBU RAYA REGENCY
Authors: Irsan Robby , Soeryamssoeka SB. , Fitrianingsih Yulisa
Published: July 2023

Prospects in tourism especially rice field tourism are being encouraged so that rural communities become independent both financial and sectoral. The concept of a tourism village is a form of community based tourism (CBT). The concept used in CBT is closely related to empowerment. Based on the identification and analysis of the problem, the solution that can be given is to develop community-based and sustainable tourism, to avoid uncontrolled land conversion, to raise public awareness by implementing environmental-based economic management and to harmonize the understanding of land owners to farming communities in ecotourism land management sustainable fields. The problems identified from the results of the FGD are the level of knowledge, attitudes, motivation, and experience of farmers towards the establishment of ecotourism in rice fields. This research was conducted using the PRA (Participatory Rural Appraisal) approach. Several techniques for implementing PRA include: (a) historical path tracing, (b) development needs tracing, (c) livelihood analysis, (d) preparation of activity plans, (e) focus group discussion, (f) mapping. The outputs from this research are (1) roadmap for developing Punggur Kecil agro-tourism village. (2) capacity building of knowledge, attitude, motivation, and experience of farmers in the development of ecotourism in paddy fields. The stages of implementing this research are planning, coordination with village government and land owners, group discussion forums, making a rice field ecotourism road map, mentoring, and monitoring and evaluation.
APPLICATION OF THE PENMAN-MONTEITH METHOD TO DETERMINE THE CROP WATER REQUIREMENTS
Authors: Arzita Tasya Dyta , Nurhayati Nurhayati , Gunarto Danang
Published: July 2023

Agricultural production is critical to meeting Indonesia's food demands. The water catchment area of Parit Keladi 1, located in Desa Parit Keladi, Kecamatan Sungai Kakap, Kabupaten Kubu Raya, Provinsi Kalimantan Barat, includes tidal swamp land that has a variety of plants. The Cropwat 8.0 Software will be used in this research to assess crop water needs. This research employs primary and secondary data, including soil samples, field cropping patterns, and plant hydration levels.The type of clay soil was silty, the field cropping pattern at the study site was paddy, and the height of the water puddle on paddy was 3 mm/day/ha, according to the findings of primary data analysis on soil sampling. The maximum water need for paddy was 5.90 mm/day/ha in March period 1, while the lowest water requirement was 0 mm/day/ha in October period 1. The maximum water need for citrus was 2.62 mm/day/ha in August for period 3, while the lowest water requirement was 0 mm/day/ha from October to December and May to June for period 1. In September Period 3, the crop water required in the Cropwat 8.0 Software was 32.2 mm/day/ha for ten days; however, the water level in the field was 3 mm/ha for one day in late September. Thus, the estimate of water demands for rice plants using the Cropwat 8.0 Program is valid.
STUDY OF WAVE HEIGHT POTENTIAL FOR DETERMINING THE LOCATION OF WECS IN THE WATERS OF KETAPANG REGENCY BY USING CEDAS SOFTWARE
Authors: Suratman Teguh , Danial Mochammad Meddy , Lestari Arfena Deah , Meirany Jasisca , Supriyadi Asep
Published: July 2023

Ketapang Regency's increasing demand for electrical energy could lead to an energy crisis. According to these issues, the Sungai Kinjil and Kinjil Pesisir coastal communities in the Ketapang Regency have wave potential that can be used as energy for marine wave power plants. As a result, The expertise required to evaluate ocean wave resources and determine the output power of electrical energy produced by ocean waves. CEDAS and ArcGIS software is used for wave modeling, with CEDAS input data in the form of wave forecasting from BMKG wind data, bathymetry, and coastline data obtained from the official Indonesia Geospatial website, and primary data in the form of wave electric power measurement data obtained from Wave energy conversion system prototypes. CEDAS processing results show the highest wave height of 0,998 meters at a depth of 1,3 meters. The potential for electrical energy at the research site is 1,908–4,512 kw/m2.
POD-based ROM applied to unsteady free surface water flow
Authors: Solán Fustero Pablo , Gracia José Luis , Navas-Montilla Adrián , García-Navarro Pilar
Published: July 2023

The numerical resolution of shallow water equations (SWE) is required in many environmental problems involving free surface flows. The upwind augmented Roe’s method [2] is widely used due to the robust and stable solutions it offers in realistic scenarios if properly corrected to deal with entropy fix and wet–dry fronts. On the other hand, reduced-order models (ROMs) are known to achieve more efficiency in terms of computational cost without losing accuracy. In this work, we analyse the properties and performance of a proper orthogonal decomposition (POD) based ROMs for this type of flows.
Focalización de ablación tumoral basada en sistema de electroporación versátil multi-salida
Authors: Briz Zamorano Pablo , López-Alonso Borja , Sarnago Héctor , Burdío José Miguel , Lucía Óscar
Published: July 2023

La ablación tumoral mediante IRE ya es empleada a nivel clínico, mas tiene diversos retos por superar, como la focalización del tratamiento, preservando tejido sano y asegurando su eficacia. Este trabajo propone una metodología basada en un sistema experimental de electroporación para mejorar el control y la focalización del tratamiento.
Caracterización experimental de resistencias integradas nano-CMOS a temperatura criogénica
Authors: Marqués-García Jorge , Pérez-Bailon Jorge , Sánchez Azqueta Carlos
Published: July 2023

Este trabajo estudia el comportamiento de resistencias integradas en tecnología CMOS en un rango de temperaturas que abarca de temperatura ambiente hasta ultra-baja temperatura (4 K). Se demuestra que el coeficiente de temperatura α no puede ser aproximado de forma lineal aun cumpliendo la condición de aproximación (αΔT<<1) para temperaturas criogénicas.
Infestation of white mustard agrocenosis, depending on agricultural practices in the conditions of the forest-steppe of the Middle Volga region
Authors: Gushchina Vera Aleksandrovna , Lykova Anna Sergeevna , Korolev Alexander Sergeevich
Published: July 2023

To obtain environmentally friendly products, in the technology of cultivating agricultural crops, the basis of modern weed control should be agricultural practices. In this regard, the purpose of the research is to select the optimal seeding rate and sowing method for white mustard, which increase the self-regulation of the number of weeds in the agrocenosis to obtain the highest seed yield. The experiment was carried out in 2020–2022 on the meadow-chernozem soil of the experimental plot of the Federal State Budgetary Educational Institution of Higher Education Penza State Agrarian University. The weather conditions during the years of research were different, but they met the requirements for the growth and development of white mustard. The growing season of mustard in the first and third years passed under conditions of sufficient moisture at the optimum temperature regime (HTC 1.3 and 1.0, respectively). In the second year of research, drier conditions developed, when the hydrothermal coefficient was 0.87. On average, the minimum infestation of mustard crops before harvesting was traced with an ordinary sowing method of 36-51 pcs/m2 with a wet weight of weeds of 75.8-106.0 g/m2, while with a wide-row method their number was 43-62 pcs/m2 with a mass of 91.0-129.2 g/m2, where the feeding area increased not only for cultivated, but also for weeds. Moreover, the agrocenosis was the cleanest with the maximum seeding rate (3 million germinating seeds/ha) and mustard sowing with a row spacing of 15 cm, where the vegetative mass actively suppressed weeds. The highest infestation in terms of quantity and weight of the weed component was established at a rate of 1.5 million and mustard sowing with a row spacing of 30 cm. Plants with row sowing with a seeding rate of 2.0-2.5 million germinating seeds/ha were more competitive, while providing a maximum oilseed yield of 2.46-2.58 t/ha.
Desarrollo de un recubrimiento comestible a base de quinoa y quitosano reforzado con aceites esenciales de hierba limón y canela encapsulados en partículas de sílice mesoporosa
Authors: Bautista-Espinoza P.I. , Di Pierro P. , Amaya-Llano S.L. , Mares-Mares E. , García-Almendarez B.E. , De la Cruz-Velázquez G. , Regalado-González C.
Published: July 2023

La contaminación por hongos es común en la industria de la panificación y para prevenirla se han usado aditivos alimentarios, los cuales se ha cuestionado recientemente. Los agentes antifúngicos naturales podrían ser una alternativa para evitar el deterioro en el pan, cuando se aplican como parte de un recubrimiento para extender su vida de anaquel. El objetivo del presente trabajo fue diseñar y caracterizar un recubrimiento comestible a base de quitosano (QT), proteína de quinoa (QU) y mezcla de aceites esenciales de canela (CA) y hierba limón (HL) para evaluar su actividad en pan artesanal. Se usó un diseño factorial 22 usando la relación QT:QU (1:4 y 1:9 w/w) y  los aceites esenciales (1:1 y 1:2 HL:CA v/v). Se determinaron las propiedades fisicoquímicas, mecánicas, estructurales y antifúngicas de los recubrimientos. El tratamiento con relación 1:4 (QT:QU) inhibió  al 63% el crecimiento de Rhizopus stolonifer, con tamaño de partícula de 2.81±0.13 µm, índice de polidispersión de 0.77±1.4 y potencial ζ de 26.4±1.3 mV. Los tratamientos 1:4 y 1:9 (QT:QU) demostraron propiedades mecánicas similares, aunque el recubrimiento 1:4 demostró tener una estructura más homogénea. Se espera que el recubrimiento comestible diseñado otorgue un impacto positivo en la vida de anaquel del producto.
Efecto del aceite esencial de orégano sobre el fruto de aguacate Persea americana
Authors: Martínez-Rojas J. , Sinagawa-García S.R. , Preciado-González P. , López-Puga J.C. , Rico-Costilla D.S. , Luna-Maldonado A.I. , Kawas J.R. , Méndez-Zamora G.
Published: July 2023

México es el principal productor mundial de aguacate, con desafíos en la cadena de suministro: reducir pérdidas en su producción. El objetivo del presente estudio se desarrolló para evaluar el aceite de orégano emulsificado (AEOE) en el aguacate analizando el peso, características métricas, color de la cáscara, pH y firmeza de la pulpa. Los grupos experimentales fueron T0: aguacates inmersos en agua sin AEOE, T200, T400 y T600: aguacates inmersos en agua con 200, 400 y 600 mg/L de AEOE, respectivamente. El peso más alto lo representó T400 y T200 menor pérdida de peso (PP). T200 y T600 presentaron mayor diámetro, y T200 la circunferencia más grande. L*, a*, b* y Chroma (saturación) de la cáscara de los aguacates aumentaron para los aguacates tratados con AEOE. El efecto de los tratamientos fue significativo (p<0.05) para la firmeza, no así (p>0.05) en el pH, siendo T600 el mayor. El AEOE a una concentración de 600 y 400 mg/L en agua podría ser utilizado para retardar el cambio de color de los aguacates, mientras que a una concentración de 200 mg/L de AEO controlaría la pérdida de peso.
Aprovechamiento de suero de leche para producción de celulosa microbiana
Authors: Salazar-Manzanares M. , Márquez-Reyes J. , Rodríguez-Romero B. , Méndez-Zamora G. , Luna-Maldonado A. , Treviño-Garza M.
Published: July 2023

Uno de los principales sectores de la industria que genera gran cantidad de aguas residuales con alta concentración de carga orgánica es el sector lácteo. El suero de leche es el residuo más representativo, ya que ha sido categorizado como un desperdicio por sus elevados volúmenes generados, ocasionando problemas severos de contaminación. El objetivo de la presente investigación fue utilizar un consorcio de microorganismos aislados de Kombucha capaz de reducir la carga orgánica del efluente utilizándolo como fuente de carbono para la producción de celulosa microbiana. Las características fisicoquímicas del suero se monitorearon durante 12 días de fermentación. Las variables respuestas fueron: % acidez titulable (At); pH; azucares totales (AT); sólidos totales (ST); sólidos totales volátiles (STV); demanda química de oxígeno (DQO); proteínas (P) y peso de la celulosa bacteriana (PCB).  Se observaron diferencias significativas para % At, pH, DQO, P. El tratamiento que presentó mayor remoción de carga contaminante del efluente fue el T1 (100;0) v/v, incrementando en él % de At; el pH disminuyó de 5.5 a 3.5; las concentraciones (At) disminuyeron de 32.7 a 7.2 g/L-1 finalmente la DQO descendió de 172.25 a 63.75 g/L-1, además de presentar aumento de la PCB.
Comparación sensorial de una bebida fermentada de Maíz (Tejuino) y una bebida fermentada de sorgo rojo
Authors: Cuevas-Guevara M. de L. , Mendoza-Gamiño H. , Espitia-Orozco F.J. , Ramos-Del Villar I.N.
Published: July 2023

El tejuino es una bebida tradicional fermentada de origen mexicano, la cual es elaborada utilizando como base la harina o masa de maíz nixtamalizada. Esta bebida ha demostrado tener un alto valor nutricional y además un valor agregado al tener diversos microorganismos de origen probiótico dentro de ella, por lo cual elaborar una bebida fermentada de sorgo rojo utilizando la misma metodología nos podría generar, una bebida con características similares, ya que el sorgo le conferirá un alto valor proteico y una fuente rica de carbohidratos. En el presente proyecto se formulo una bebida fermentada de sorgo rojo “tipo tejuino” y fue comparada sensorialmente con una bebida fermentada de maíz “tejuino”. De acuerdo con las evaluaciones sensoriales realizadas por los jueces se observó que existen diferencias significativas entre ambas bebidas y se determinó una mayor aceptabilidad de la bebida fermentada de sorgo rojo.