bluuebunny/crossref_metadata_2025 huggingface dataset:
Metodología y evaluación de recursos energéticos renovables: implementación de microrredes aisladas
Authors: Lopez Castrillon Yuri Ulianov , Gaviria Cataño Fabian Andrés
Published: October 2019

En América Latina más de 100 millones de personas no tienen acceso a una energía limpia, asequible y constante. En Colombia, esto sucede en las denominadas Zonas No- Interconectadas - ZNI con una población de más de 2 millones de personas, que viven en regiones con abundantes y diversos recursos energéticos renovables. En este artículo se presenta una metodología para el diseño de microrredes en zonas aisladas, partiendo de la evaluación de recursos energéticos renovables locales. Una microrred es un sistema que usa varias fuentes y utiliza tecnologías de conversión de energías renovables en electricidad para proveer de electricidad zonas asiladas. Estas “microrredes” inteligentes consisten en un sistema energético que integra la generación, transmisión, distribución y uso final de la energía, de manera eficiente y amigable con el medio ambiente, y con un mínimo impacto socio-cultural, permitiendo el intercambio de información entre todos los componentes del sistema para un óptimo control. Por ello, es de suma importancia desarrollar un acertado análisis y evaluación de recursos energéticos, con el objetivo de optimizar al máximo el diseño de microrredes
Evaluación de la usabilidad de los EVA (entornos virtuales de aprendizaje) a partir de la experiencia de usuarios aplicando lógica difusa
Authors: Díaz Gutiérrez Edilma Leonor , Valderrama García Cesar Fernando
Published: October 2019

La forma más adecuada para evaluar la calidad de una plataforma de formación virtual libre o propietaria es a partir del análisis de la usabilidad por parte de usuarios, quienes a través de su percepción facilitan la cuantificación de dicho factor que servirá de guía para la selección y adquisición de este tipo de aplicaciones por las instituciones de educación. Con el fin de cuantificar en forma más exacta dicha valoración, se propone diseñar un modelo de lógica difusa basada en la experiencia del usuario, el cual integra variable de medición de la usabilidad para la generación de datos más exactos que los métodos cualitativos ya utilizados, y que demuestran que el grado de pertenencia de la variable de salida (usabilidad) de las plataformas propietarias es mayor, lo que obliga a los desarrolladores a cuestionarse un poco más en torno a las características y servicios de los productos que desarrollan.
Science-policy boundary work by early-stage researchers: Recommendations for teaching, internships and knowledge transfer
Authors: Paschke Melanie , Zurgilgen Karina
Published: October 2019

Establishing mechanisms for involving scientists in policymaking for the Sustainable Development Goals (SDGs) is a long-term requirement. The Zurich-Basel PhD program Science and Policy involves early-stage scientists in science-policy boundary work through internships
and co-supervision at academic and policy institutions. In a Delphi study, students reported to have acquired new skill sets for science-policy dialogue. However, challenges remain, including the lack of time for policy work during a PhD project or the different incentive systems in academia
and policy.
Urbane Produktion: Ökonomischer Impuls, soziale Chance und ökologischer Mehrwert für die Zukunftsstadt
Authors: Betker Frank , Libbe Jens
Published: October 2019

Ein neuer Trend macht sich bemerkbar: Dank ,,urbaner Produktion“ wird die Stadt wieder Produktionsort für innovative und digitale Güter. Was Vorteile wie kulturelle Vielfalt und soziale Stabilität verspricht, kann aber auch zu Konflikten führen, wenn sich die
tradierte Aufteilung des Stadtraums in Gebiete für Wohnen, Konsum, Industrie, Verkehr und Freizeit allmählich auflöst und sich Nutzungen stärker mischen. Die Sozial-ökologische Forschung ist gefragt, hier nach Lösungen zu suchen.
Das Format ,,Reallabor“ weiterentwickeln: Best-Practice-Beispiel Karlsruher Transformationszentrum
Authors: Parodi Oliver , Seebacher Andreas , Albiez Marius , Beecroft Richard , Fricke Annika , Herfs Lea , Meyer-Soylu Sarah , Stelzer Volker , Trenks Helena , Wagner Felix , Waitz Colette
Published: October 2019

Reallabore sind in der Forschungslandschaft inzwischen sehr populär. Das Format steckt aber immer noch im Anfangsstadium, ist selbst noch mehr Experiment denn Labor. So fehlen Reallaboren häufig eine langfristige Perspektive sowie eine gleichberechtigte Unterstützung
aus Wissenschaft und Gesellschaft. Das sich im Aufbau befindende Karlsruher Transformationszentrum zeigt, wie diese Schwächen behoben werden und Reallabore langfristig sozial-ökologische Transformationen gestalten können.
Developing 21st century skills for the first language classroom: Investigating the relationship between Chinese primary students’ oral interaction strategy use and their group discussion performance
Authors: Zhu Xinhua , Loh Elizabeth K. Y. , Yu Guoxing , Tam Loretta C. W. , Liao Xian
Published: October 2019

Given the increasing awareness of oral communication in this era of globalized collaborative learning trends, there is an imminent need to inform language educators of ways in which the under-researched oral interactional strategies are related to first language (L1) teaching. However, no consensus has yet been reached on the relationship between interactional strategy use and oral language proficiency. This study investigates the effect of oral interactional strategy use on group discussion performance in L1 Chinese for Primary 5 students (N = 140) in Hong Kong. Based on ANOVA and regression analyses of the data on group discussion performance, five strategies have been identified: expressing actively, asking for opinion, expressing attitude, giving clarification and non-verbal language. They all significantly predicted students’ group discussion performance, with overall strategies explaining 55.5% of total variation of the performance, where higher-proficiency students tended to use more strategies that enable comprehension and elaboration in the group discussions. The patterns of strategy use among students with different levels of discussion performance have also been identified. Implications of the findings are discussed with reference to the roles individuals play in the overall performance of group discussion.
Task scheduling algorithm based on multi criteria decision making method for cloud computing environment: TSABMCDMCCE
Authors: Mukherjee Proshikshya , Pattnaik Prasant Kumar , Swain Tanmaya , Datta Amlan
Published: October 2019

This Paper focuses on multi-criteria decision making techniques (MCDMs), especially analytical networking process (ANP) algorithm to design a model in order to minimize the task scheduling cost during implementation using a queuing model in a cloud environment and also deals with minimization of the waiting time of the task. The simulated results of the algorithm give better outcomes as compared to other existing algorithms by 15 percent.
A Culture-Independent Method for Enumeration of Viable Load of Lactobacillus acidophilus NCFM by using Real-Time PCR
Authors: Ali Md. Aslam , Zhang Ziwei , Li Hongfu , Zhang Yashuo , Fu Shiqian , Zhang Wei , Man Chaoxin , Jiang Yujun
Published: October 2019

The study was performed to develop a non-culture method to quantify viable loads of Lactobacillus acidophilus NCFM using RNA-based molecular technique. The ‘growth curve’ and ‘cycle threshold curve’ were developed respectively by plate counting and using cycle threshold (CT) values. ‘Standard curve’ was constructed using cells per milliliter and relative CT values. A maximum viable count (1.5 ± 0.15) × 1010 cells/mL with a minimum CT value 20.18 ± 0.56 was achieved following 18 h of growth. The two parameters were inversely proportional to each other over the exponential growth. The ‘standard curve’ corresponded to equation y = 2E + 28e−2.034x (y = cells/mL, x = CT value; R2 = 0.993), and no sample showed significant difference between ‘plate count’ and relative ‘PCR count’ following the validation process. Industrial adaptation of this method in dairy processing could potentially contribute to a faster enumeration of viable L. acidophilus NCFM compared to plate counting.
Long non-coding RNA HCP5 serves as a ceRNA sponging miR-17-5p and miR-27a/b to regulate the pathogenesis of childhood obesity via the MAPK signaling pathway
Authors: Chen Rui , Xin Guangda , Zhang Xiaofei
Published: October 2019

Background

This study aimed to investigate the completing endogenous RNA (ceRNA) network involved in childhood obesity.

Methods

The microarray dataset GSE9624 was downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed long non-coding RNAs (lncRNAs) (DELs) and messenger RNAs (DEMs) were isolated between the childhood obesity and non-obesity tissue samples. Then, Gene Ontology (GO) functional and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses of isolated DEMs were performed. DELs and DEMs targeted miRNAs were predicted to construct a ceRNA regulatory network. Finally, critical lncRNAs were validated in another dataset.

Results

A total of 1257 differentially expressed RNAs were screened, including 28 lncRNAs and 1229 mRNAs. In addition, these RNAs were mainly involved in defense response, cell cycle, mitogen-activated protein kinase (MAPK) signaling pathway, apoptosis, etc. Three lncRNAs (human leukocyte antigen complex 5 [HCP5], long intergenic non-protein coding RNA 839 [LINC00839] and receptor activity modifying protein 2 [RAMP2-AS1]) and two related miRNAs (hsa-miR-17-5p and hsa-miR-27a/b-3p) were identified as key RNAs in childhood obesity. Specifically, lncRNA HCP5 interacted with miR-17-5p and miR-27a/b to regulate nemo-like kinase (NLK) and Ras-related protein 2 (RRAS2) via the MAPK signaling pathway. Finally, four genes (RRAS2,NLK, bcl2/adenovirus E1B protein-interacting protein 3 [BNIP3] and phorbol-12-myristate-13-acetate-induced protein 1 [PMAIP1]) targeted by miRNAs were predicted as critical genes and might be novel diagnostic biomarkers of childhood obesity.

Conclusions

lncRNA HCP5 could serve as a ceRNA sponging miR-17-5p and miR-27a/b to regulate the pathogenesis of childhood obesity viaNLKandRRAS2in the MAPK signaling pathway.
Measurement of inferior facial angle and prefrontal space ratio in first trimester fetuses with aneuploidies: a retrospective study
Authors: Tekesin Ismail , Graupner Oliver
Published: October 2019

Objective

To determine whether the measurement of inferior facial angle (IFA) and prefrontal space ratio (PFSR) in two-dimensional (2D) ultrasound images in the first trimester of pregnancy is reliable and to describe these markers in normal and aneuploid fetuses.

Methods

IFA and PFSR were measured in stored 2D midsagittal images of 200 normal and 140 aneuploid fetal profiles between 11 + 0 and 13 + 6 weeks of gestation. Limits of agreement (LOAs) and intraclass correlation coefficients (ICCs) for inter- and intraobserver differences were calculated.

Results

The mean IFA in normal fetuses was 76.5° ± 6.3. Between the two measurement rounds of the same observer, the LOAs were −5.4 to 7.1 (obs. 1) and 7.4 to 8.4 (obs. 2). For IFA measurements by the same observer the ICC was 0.88 (obs. 1) and for measurements by two different observers the ICC was 0.74. The mean PFSR was 0.76 ± 0.40 and the intraobserver LOAs were −0.372 to 0.395 (obs. 1) and −0.555 to 0.667 (obs. 2). For PFSR measurements by the same observer the ICC was 0.89 (obs. 1) and for measurements by two different observers the ICC was 0.65. Among aneuploid fetuses, IFA was below the normal range in one third of the cases with trisomy 18. PFSR was below the 95% prediction limit in 16.2% of fetuses with trisomy 21% and 17.9% of fetuses with trisomy 18.

Conclusion

IFA can be reliably measured in 2D ultrasound images in the first trimester of pregnancy with a high interobserver agreement and may provide information about retrognathia associated with various syndromes and aneuploidies at early stages of pregnancy.
Measurement in the context of technoscientific research methodology
Authors: Morawski Roman Z.
Published: October 2019

Technoscience is a result of integration of technology with empirical sciences, including not only physical sciences, but also life sciences, social sciences and cognitive sciences. Further development of technoscience is unthinkable without extensive use of measurement and mathematical modelling, being two interrelated operations used for acquisition and representation of knowledge. Measurement fundamentals must, therefore, belong to the core of methodological instruction of young researchers in the domain of technoscience. This paper provides an outline of a sought-for discipline-independent programme of such formation, including a conceptual analysis of the key elements of the scientific method, with particular emphasis on the dialectical relationship between measurement and mathematical modelling, on the role of measurement in scientific prediction and explanation, on the role of measurement in the context of discovery and in the context of justification, as well as on the role of measurement in mitigating uncertainty of scientific knowledge.
Implicaciones de la figura del outsourcing en los derechos laborales y ganancias de las empresas en México: Un análisis comparado
Authors: Ruiz Medrano Salvador Francisco
Published: October 2019

El presente trabajo pretende ser una aportación en torno a la cuestión administrativa y la visión jurídica del outsourcing que se han venido implementado en nuestro país, frecuentemente llevadas a cabo de forma contraria a la filosofía de los fines buscados en dicha figura. A través de un análisis de derecho comparado de corte internacional, se busca identificar su implementación en el mundo y las propuestas de organizaciones como la Organización de las Naciones Unidas para el Desarrollo Industrial (ONUDI).
E-learning through Google Hangouts: a tool in the teaching-learning process of EFL
Authors: Fernández Sánchez Higinio , Enríquez Hernández Claudia B. , Fernández Blanca Flor , Martínez Díaz Nazaria , Santes Bastian María del Carmen
Published: October 2019

As today’s world becomes a networked society, Information and Communication Technologies (ICT) have become powerful contributors towards the acquisition of a foreign language. The aim of this study is to examine the feasibility of implementing a technology-based program: the English as a Foreign Language (EFL) students’ satisfaction with the program and the perceived benefits in improving their English skills (speaking, listening, reading, and writing). A one-group, pretest-posttest design was used. A six-week technology-based program, with 30 min sessions, was implemented once a week. A total sample size of 20 students enrolled in a one-day advanced EFL course. There was a high satisfaction towards the program (80%) and towards the facilitator (100%). Fifty percent of participants considered the Hangout sessions as very helpful in developing their speaking skill, 75% considered them to be very helpful for their listening skill., and 50% reported the Hangout sessions to be somewhat helpful in developing their reading skill and their writing skill. Even though taking time to work outside of the classroom had its challenges, the virtual environment led to the collaboration between students, who demonstrated high commitment during the sessions, allowing their writing, reading, speaking and listening skills to improve.
Obtención de las propiedades mecánicas de la mampostería de adobe mediante ensayes de laboratorio
Authors: Catalán Quiroz Policarpo , Moreno-Martínez Jatziri Yunuén , Galván Arturo , Arroyo Matus Roberto
Published: October 2019

En este artículo se presentan los resultados obtenidos de pruebas experimentales realizadas a una muestra aleatoria de pilas y muretes de adobe. Se describen los procedimientos de construcción de las piezas de adobe, probetas, especificaciones de ensaye, análisis de resultados y caracterización de las principales propiedades mecánicas del adobe: módulo de elasticidad, resistencia a la compresión, cortante y flexión. Esto, debido a la necesidad primordial de una norma, pues actualmente no existe, para realizar los ensayes en este tipo de material, resaltando que el 50% de la población en países en desarrollo viven en construcciones de tierra. Asimismo, se describen las características principales de la vivienda de adobe en el estado de Guerrero (zona Sureste de México), sus materiales de construcción y componentes estructurales de las viviendas típicas de está región de la República Mexicana. Se concluyó que el 40% del esfuerzo de compresión máximo especificado en la norma NMX para calcular el módulo de elasticidad y el módulo de rigidez al corte no representa el valor que se debe utilizar para la mampostería de adobe. Esto debido a que el adobe mantiene su rama elástica en valores de aproximadamente 15%-20% el valor del esfuerzo de compresión máximo.
Evaluación de la calidad del agua residual para el riego agrícola en Valle del Mezquital, Hidalgo
Authors: Pérez-Díaz José Pedro , Ortega-Escobar Héctor Manuel , Ramírez-Ayala Carlos , Flores-Magdaleno Héctor , Sánchez-Bernal Edgar Iván , Can-Chulim Álvaro , Mancilla-Villa Oscar Raúl
Published: October 2019

En este estudio se determinó la concentración de los iones Ca2+, Mg2+, Na+, K+, CO32-, HCO3-, Cl- y SO42-, pH y conductividad eléctrica (CE) en el agua residual proveniente de la Ciudad de México. El objetivo fue evaluar la calidad del agua y estimar el riesgo de salinización y sodificación de los suelos irrigados en Valle del Mezquital. El agua residual se clasificó como bicarbonatada-sódica con pH ligeramente alcalino (Q3 = 8.11). Los valores mínimo y máximo de CE fueron 0.278 dS m-1 y 3.684 dS m-1 (Q3 = 1.890 dS m-1), la relación de adsorción de sodio (RAS) fue menor de 14.12 mmol L-1 en 95% de las muestras de agua. El promedio estimado del porciento de sodio intercambiable (PSI) para un suelo arenoso fue 5.95, para el franco 9.34 y para el arcilloso 12.74. El uso del agua residual en la irrigación de cultivos puede inducir procesos de salinización y sodificación en el suelo.
Macromycetes of the San José educational park, municipality of Zinacantan, Chiapas, Mexico
Authors: Chanona-Gómez Freddy , Alvarez Gutiérrez Peggy Elizabeth , Pérez-Luna Yolanda del Carmen
Published: October 2019

Chiapas is one of the most biodiverse regions of our Planet; however, the knowledge of tropical mushrooms in this state is limited. As a consequence of this lack of information of the mycobiota of Chiapas and areas such as San José (SJ) park, it is very important to carry out inventories of biotic resources as a basic and fundamental research tool for some protected areas, in order to develop studies for conservation. This study aims to prepare a list of the macrofungi species in the SJ park. Specimens were collected along five consecutive years, and 148 species (21 Ascomycetes and 126 Basidiomycetes) were identified. The most common substrate was humus (110 species, 74.82%). Forty-six species that can be used for human consumption were found. Thus, the mycological value for the study area was 31.29%. Also, 27 new records for Chiapas (5 Ascomycotina and 22 Basidiomycotina) were found.
Factores de la teoría de Herzberg y el impacto de los incentivos en la satisfacción de los trabajadores
Authors: Madero Gómez Sergio Manuel
Published: October 2019

Nowadays, companies need to develop and design attraction and retention strategies to help their employees be more productive and to find, through financial compensations, a stable source of income that meets their economic needs. This research work shows the preference and impact that the factors of the Herzberg’s theory have on job satisfaction. In this quantitative research, a questionnaire with 25 items was designed and applied to 423 people who work in Monterrey, Nuevo León, Mexico. It is highlighted that the recognition schemes (AV = 4.64 SD = 0.77) and the autonomy to make decisions (AV = 4.64 SD = 0.68) are the most important non-monetary aspects, whereas the Christmas bonus (AV = 4.69 SD = 0.62) is the most important from the monetary perspective.
La importancia de la participación y corresponsabilidad en el manejo de los residuos sólidos urbanos
Authors: Del Carmen Niño Viridiana , Rodríguez Herrera América L. , Juárez López Ana Laura , Sampedro-Rosas Maria Laura , Reyes-Umaña Maximino , Silva-Gómez Sonia E.
Published: October 2019

El manejo de los residuos sólidos urbanos (MRSU) en Xaltianguis es realizado por la misma comunidad, generando contaminación y deterioro ambiental. Este artículo estudia el MRSU enfocándose en la participación comunitaria. Para estimar la generación, composición y emisión se aplicó la calculadora del clima. El MRSU se obtuvo mediante una encuesta y entrevistas. Los tiraderos a cielo abierto (TCA) se georreferenciaron utilizando los sistemas de información geográfica, cuyos resultados mostraron una generación de 1017 toneladas anuales (t/a) de residuos; 62.1% fueron orgánicos y emitían 1036 t/a de CO2-eq. Existían dos sistemas de recolección, el municipal operaba semanalmente, mientras el informal a diario depositaba en un TCA y se registraron otros 22 TCA. El 48% de la población considera participar. Prácticas como el reúso (44%) y reciclaje (2.3%) aportarían a un eficiente MRSU, pero este solo puede lograrse con corresponsabilidad y compromiso de la comunidad y el municipio.
Psychopathy as an Emergent Interpersonal Syndrome: Further Reflections and Future Directions
Authors: Lilienfeld Scott O. , Watts Ashley L. , Murphy Brett , Costello Thomas H. , Bowes Shauna M. , Smith Sarah Francis , Latzman Robert D. , Haslam Nick , Tabb Kathryn
Published: October 2019

In our article (Lilienfeld et al., 2019), we hypothesized that psychopathy and some other personality disorders are emergent interpersonal syndromes (EISs): interpersonally malignant configurations of distinct personality subdimensions. We respond to three commentaries by distinguished scholars who raise provocative challenges to our arguments and intriguing suggestions for future research. We clarify the role of folk concepts in our understanding of psychopathy, offer further suggestions for testing our interactional hypotheses, consider the role of boldness in motivational accounts of psychopathy, and discuss future directions for incorporating developmental considerations and the role of victims in our EIS account. We are optimistic that this account will prove to be of heuristic value, and should encourage researchers and theoreticians to explore alternative models of psychopathy and other personality disorders.
Transcriptome Characterization of Reverse Development inTurritopsis dohrnii(Hydrozoa, Cnidaria)
Authors: Matsumoto Yui , Piraino Stefano , Miglietta Maria Pia
Published: October 2019

Medusae of Turritopsis dohrnii undergo reverse development in response to physical damage, adverse environmental conditions, or aging. Senescent, weakened or damaged medusae transform into a cluster of poorly differentiated cells (known as the cyst stage), which metamorphose back into a preceding life cycle stage, the polyp. During the metamorphosis, cell transdifferentiation occurs. The cyst represents the intermediate stage between a reverting medusa and a healthy polyp, during which cell transdifferentiation and tissue reorganization take place. Here we characterize and compare the transcriptomes of the polyp and newborn medusa stages of T. dohrnii with that of the cyst, to identify biological networks potentially involved in the reverse development and transdifferentiation processes. The polyp, medusa and cyst of T. dohrnii were sequenced through Illumina RNA-sequencing and assembled using a de novo approach, resulting in 92,569, 74,639 and 86,373 contigs, respectively. The transcriptomes were annotated and comparative analyses among the stages identified biological networks that were significantly over-and under-expressed in the cyst as compared to the polyp and medusa stages. Biological processes that occur at the cyst stage such as telomerase activity, regulation of transposable elements and DNA repair systems, and suppression of cell signaling pathways, mitotic cell division and cellular differentiation and development may be involved in T. dohrnii’s reverse development and transdifferentiation. Our results are the first attempt to understand T. dohrnii’s life-cycle reversal at the genetic level, and indicate possible avenues of future research on developmental strategies, cell transdifferentiation, and aging using T. dohrnii as a non-traditional in vivo system.
Emotions and Images in Li Qingzhao’s Ci Poetry: Quantitative Analysis
Authors: Dashchenko Hanna
Published: October 2019

This article deals with ci written by the outstanding Chinese poetess of the Song dynasty Li Qingzhao (李清照, 1084–1155?) and her poetic style Yi’an ti (易安體). The empirical material for this research is the extant 60 ci of Li Qingzhao which are presented in one of the most famous collections compiled by Xu Peijun (徐培均). Having analyzed these ci I have found several correlations concerning her poetic style. Firstly, in Li Qingzhao’s poetry ci form is positively related to ci rank: the longer ci, the higher its chance of being perceived as an “outstanding” one by commentators and poets. Secondly, the way of expressing emotions is one of the main elements that make Li Qingzhao’s long ci (zhongdiao 中調 and changdiao 長調) to be perceived as the “outstanding” ones by commentators and poets and her short ci (xiaoling 小令) as nothing very distinctive. Thirdly, negatively marked emotions are dominant in Li Qingzhao’s ci, but in most cases the poetess did not mention the reason of the sorrow of the lyrical persona or the persona this emotion was connected with. Forthly, there is a strong correlation between ci form, ci rank and types of floral images in her poetry.
Potential and limitations of post-crisis recovery of Ukrainian mortgage market
Authors: Bublyk Yevhen
Published: October 2019

The article analyzes the structural characteristics of the mortgage lending market caused by the impact of financial and economic crisis.
The evaluation of government programs to support housing mortgage loans is conducted,conclusions and recommendations are made on future actions for the resumption of bank mortgage lending through improving institutional structure, legal support and government programs.
IDENTIFICATION OF VARIATIONS IN THE CODING REGION OF MYOSTATIN (MSTN) GENE OF THALLI AND PAK-KARAKUL SHEEP BREED IN PAKISTAN
Authors: Ahmed Wadood Armughan , Sadia Haleema , Yangqing Lu , Hussain Tanveer , Safdar Muhammad , Shahzad Qaisar , Ashiq Kanwal , Ali Asad , Ashiq Sana
Published: October 2019

Marker assisted selection (MAS) is a potential tool to genetically enhance the traits of economic importance in livestock production. One of the gateways to MAS is the identification of SNPs for the desired genes. The aim of the present study was to detect SNPs in myostatin (MSTN) gene which has a negative role in growth and skeletal muscle development. Therefore, polymorphisms of the exon no 1, 2 and 3 of MSTN gene were studied in Thalli (n=10) and Pak-karakul (n=10) sheep breeds. The genomic DNA was isolated and amplified by using PCR. The amplicons were purified and sequenced. After PCR all samples were sent to Singapore for 1st base laboratory for further purification and sequencing. Sequencing analysis was done using Codon Code Aligner and MEGA 6 software’s. Mutations were observed at only exon no 1 in 50% (5/10) Thalli sheep (heterozygous G>T =3/5, synonymous =2/5) and 20% (2/10) Pak-karakul sheep (only synonymous T mutations) at 3995bp. The two alleles (A and B) were found having all the three combinations of genotypes i.e. AA, AB and BB. Allele frequencies (A+B) were 0.2 and 0.8 in Pak-karakul and in case of Thalli it was 0.5 in each. The data from the present study suggests that SNPs in MSTN gene are present. Furthermore, scope of the present study may be enhanced to establish a marker for improved mutton production through conducting association studies at large scale.
JUMBO SQUID (Dosidicus gigas) SKIN PIGMENTS: CHEMICAL ANALYSIS AND EVALUATION OF ANTIMICROBIAL AND ANTIMUTAGENIC POTENTIAL
Authors: Enrique Chan-Higuera JesÃºs , Antonio Carbonell-Barrachina Angel , Luis Cárdenas-López JosÃ© , Kačániová Miroslava , Burgos-Hernández Armando , Marina Ezquerra-Brauer Josafat
Published: October 2019

There is a great potential to use seafood by-products to create new beneficial products for customers. In a continued exploration of new chemical compounds from seafood by-products, jumbo squid (Dosidicus gigas) skin pigmented methanolic extracts (JSSE) were evaluated for their antimicrobial and antimutagenic activities. Pigments of JSSE were extracted with a yield of 635 mg/g and oxygen radical absorbance capacity-fluorescein (ORAC) with 178 mol TE/g JSSE using optimal conditions: 25 °C and 5 min of sonication, established by factorial analysis. The antimicrobial activity of JSSE was evaluated using the agar diffusion method. The JSSE showed more than 50% inhibition against Haemophilys influenza, Listeria monocytogenes, Staphylococcus aureus, and Candida albicans. The high antimicrobial activity of JSSE (50%), but not in the TA100 strain (
El proceso enseñanza–aprendizaje y los mapas conceptuales: una reflexión desde la educación en ciencias de la salud
Authors: Correa Arias Juán David , Estrada Montoya John Harold
Published: October 2019

El mapa conceptual es un recurso útil para esquematizar, de manera visual, el conocimiento, y puede servir como herramienta para que los estudiantes, individual o colectivamente, tengan una mayor comprensión y capacidad de síntesis de los conceptos, de las relaciones y de las interacciones de los contenidos estudiados. Este artículo aborda, de manera reflexiva, el modo en que los mapas conceptuales han sido utilizados en la enseñanza en las ciencias de la salud y la manera en que aportan a los análisis que los estudiantes adelantan en su proceso de aprendizaje. La enseñanza está centrada en diseñar interacciones educativas que, a través de situaciones puntuales, involucren el conocimiento de diversas disciplinas en un saber particular. Para el caso de la educación científica, tales interacciones involucran cuatro dimensiones en el proceso de aprendizaje de los estudiantes: la fáctica, la conceptual, la procedimental y la metacognitiva; los mapas conceptuales son una herramienta que aporta a este proceso. El uso de mapas conceptuales amplía tanto la experiencia particular de los docentes como el horizonte de experiencias de educación en el área de la salud. La didáctica es la interacción, en diferentes vías, entre alguien que enseña, alguien que aprende; e implica una disciplina, un saber y un discurso. Usar mapas conceptuales, como herramienta didáctica, puede enriquecer la práctica pedagógica de maestros de ciencias de la salud y favorecer la construcción de escenarios de enseñanza que permitan la construcción del conocimiento conjunto, la retroalimentación del mismo, la adecuada integración y la síntesis de conceptos para su aplicación en escenarios teóricos y prácticos.
Tercer molar en la conformación de un odontoma complejo. Reporte de un caso clínico
Authors: Aguilar Novillo Jonnathan Esteban , Palacios Vivar Diego , Banegas Encalada Johnny Damian
Published: October 2019

El presente informe tiene como propósito reportar un caso clínico de odontoma complejo intraóseo ubicado en la zona posterior del tercer molar inferior derecho, molar que se encuentra retenido y que es parte principal de la estructura del odontoma. Un odontoma —o hamartoma de tejido odontogénico— es una alteración del desarrollo o malformación que presenta tejidos dentales como esmalte, dentina, cemento y pulpa. La Organización Mundial de la Salud (OMS) define los odontomas como tumores odontogénicos benignos mixtos, epiteliales y mesenquimáticos; son, por lo general, asintomáticos; su etiología no se encuentra definida —por lo que se asocian a distintos factores—; se clasifican en compuestos y complejos —en virtud de diferencias en la organización del tejido dentario—; y, regularmente, son diagnosticados mediante análisis radiográficos y con biopsias enviadas a patología. Al Paciente —de sexo masculino, 45 años, hipertenso controlado— se le realizaron radiografías panorámica y tomografía. Una vez analizados los estudios complementarios, se realizó la enucleación y la exodoncia quirúrgica los molares tercero y segundo, que resultaron afectados. Adicionalmente, se utilizó Plasma Rico en Fibrina (PRF) para rellenar la cavidad ósea. Finalmente, se realizó estudio histopatológico, donde se confirmó el diagnóstico de odontoma.
Evaluation of genetic variations and phylogeny of the most popular pear (Pyrus communis L.) cultivars in Duhok city using AFLP markers
Authors: Ali Shaymaa H. , Othman Hemin E. , Abdullah Zibari Payman A. , S. Jubrael Jaladet M.
Published: October 2019

Introduction: Genotyping and evaluation of genetic variation and polymorphic information content of the locally cultivated pear (Pyrus communis L.) might play an important role in building the genetic bank. These are also immensely important for present and future pear breeding program in the region. Methods: In the current study, AFLP markers have been employed to estimate the level of genetic diversity and to assess the phylogeny among theseven most popular pear cultivars in Duhok city. Results: Eight selective primer combinations generated a total of 653 AFLP fragments from which 445 (68.2%) fragments were polymorphic. The number of visible amplified products per primer combination were varied and ranged from 66 to 96 bands. The highestpercentage of polymorphism (78.4%) was observed by the primer pair P174/M182, while the lowest percentage of polymorphism (58.6%) was observed by the primer pair P174/M100. The highest PIC (0.85) was obtained with the primer combination P174/ M182, while, the lowest PIC (0.49) was obtained by the primer combination P174/M307. The genetic distance was ranged from 0.1348 (between Danimarki and Amreki cultivars) to 0.3131 (between Italy and Zaafaran2 cultivars). Based on the AFLP data, all the seven pear genotypes were successfully clustered into two separate clusters (C1 and C2) with an out-group of Itali cultivar. Conclusions: Overall, it can be concluded that there was high polymorphism among the studied genotypes. Also, it can be stated that the AFLP was a reliable and a powerful technique in genotyping and discriminating of respective pear cultivars.
CONCEPTUAL POSITIONS OF ENTERPRISE STRATEGY FUNCTIONING
Authors: O. Kalaman , I. Savenko , O. Dolynska
Published: October 2019

Ensuring the effective development of manufacturing enterprises requires a number of activities thatare concerned with the planning and systematic organization of its activities, making and implementing management decisions, conducting production and innovation processes and evaluating the results achieved onthe basis of the involvement of internal and external strategic impulses.The article analyzes the concept of strategy, its structure and its functions. It has been revealed thatthe task of strategic planning of activity and development of the enterprise is one of the important in the conditions of competition. Many real enterprises were not prepared for its decision. In order to understand thisprocess, it is necessary to disclose the content of the strategic approach in enterprise theory and in the practice of enterprise management. The main objective of this article is to determine the requirements for the development and implementation of strategies arising from the theoretical analysis of the internal and externalenvironment of the enterprise. In formulating the strategy of the enterprise it is important not to get lost in theinfinity of incomparable possibilities of strategic choice, to reduce the variety of these opportunities in eachline of activity of the enterprise to a discrete set of options. Developing and presenting recommendations forconducting this necessary part of strategy development and implementation is the second objective of thisarticle.
СИСТЕМА ПОСЛУГ “ALL INCLUSIVE” В АСПЕКТІ ЕКОНОМІКИ ВРАЖЕНЬ ТА ПЕРСПЕКТИВИ ЇЇ ВПРОВАДЖЕННЯ В УКРАЇНІ
Authors: О. Дишкантюк В.
Published: October 2019

У роботі здійснений аналіз системи послуг “Все включене” в аспекті економіки вражень. На ду-мку автора, економічна сутність системи “Все включено” полягає в тому, що це комплекс товарів тапослуг, які необхідні для формування вражень споживачів. Враження, які отримують гості на різнихетапах свого відпочинку, володіють корисністю, споживчою цінністю та в кінцевому підсумку маютьвартість. Вона створюється в процесі взаємодіі з постачальниками різних послуг, кожен з яких робитьсвій внесок в створення цілісного враження і тим самим формує вартість кінцевого продукту гостинно-сті. Технологічна послідовність вражень формує ланцюги доданоі вартості. І ці ланцюги обєднуютьсубєктів гостинності, як в межах одного, так і різних інфраструктурних секторів.Визначені сильні та слабкі сторони системи “Все включене”, проаналізовані загрози та можли-вості впровадження даноі системи в Україі. Охарактеризовані особливості проектування транспорт-них послуг, розміщення, харчування та анімацій системи “Все включене” в аспекті формування чоти-рьох областей вражень - розваги, навчання, відхід від реальності, естетика. Зроблено висновок щодоможливості та доцільності впровадження формули “Все включене” в умовах Україи, що дозволяє ро-звивати внутрішній туризм, утримуючи туриста всередині країи, надаючи йому все те, що він ранішеотримував за кордоном, а також залучити іноземних туристів, насамперед з ближнього зарубіжжя.Приведені рекомендаціі щодо забезпечення конкурентоздатності формули “Все включене” в умовахУкраїи. Означені напрями подальших досліджень, які полягають у необхідності проведення сегмен-тування гостей, вивчення ї ментальних особливостей, потреб, настрої, інтересів.
Estado nutricional e avaliação do tempo de jejum perioperatório de pacientes submetidos à cirurgias eletivas e de emergência em um hospital de referência.
Authors: Lucchesi Fabiana de Arruda , Gadelha Patrícia Calado Ferreira Pinheiro
Published: October 2019

RESUMO Objetivo: avaliar o perfil clínico, cirúrgico e nutricional de pacientes cirúrgicos internados em um hospital de referência da cidade de Recife - PE. Métodos: estudo de caráter transversal, realizado nas enfermarias do Serviço de Cirurgia Geral do Hospital da Restauração Governador Paulo Guerra, no período de junho a setembro de 2018. Foram incluídos pacientes adultos e idosos de ambos os sexos, submetidos a procedimentos toracoabdominais e cirurgias abdominais, de caráter eletivo ou de emergência, em que a avaliação do estado nutricional pôde ser realizada em até 72 horas da admissão hospitalar. Foram coletados dados sobre o estado nutricional, sobre os procedimentos cirúrgicos, assim como, informações clínicas e bioquímicas. Resultados: foram estudados 140 pacientes, com mediana de idade de 45 anos, 59,3% do sexo feminino, sendo que 23% apresentavam-se desnutridos, através da Avaliação Subjetiva Global. A mediana do tempo de jejum pré-operatório para as cirurgias de porte I foi de 15 horas e para as de porte II, 13,5 horas. Maior tempo de permanência hospitalar no pós-operatório apresentou forte correlação com o tempo total de internamento em ambos os portes cirúrgicos. Pacientes desnutridos apresentaram maior tempo de jejum perioperatório e de permanência hospitalar quando comparados com os bem nutridos (p<0,001). Conclusão: o tempo de jejum perioperatório das cirurgias eletivas esteve acima do que é preconizado pela literatura. Pacientes com maior tempo de jejum permaneceram mais tempo internados.
Oxygen consumption and heart rate obtained in a ramp protocol are equivalent during exercise session of rectangular loading at ventilatory thresholds for athletes
Authors: Gasparini Neto Victor Hugo , Azevedo Paulo , Carletti Luciana , Perez Anselmo José
Published: October 2019

Abstract Training near or at ventilatory threshold (VT) is an adequate stimulus to improve the thresholds for sedentary subjects, but a higher intensity is necessary for conditioned subjects. The choice of cardiopulmonary exercise testing (CPx) protocol has an influence on VTs identification and can reduce their reliability for exercise prescription. This study tested if VO2 and heart rate (HR) corresponding to first (VT1) and second ventilatory threshold (VT2) determined during a ramp protocol were equivalent to those observed in rectangular load exercises at the same intensity in runners elite athletes (EA) and non-athletes (NA). Eighteen health subjects were divided into two groups: EA (n = 9, VO2max 68.6 mL·kg-1·min-1) and NA (n = 9, VO2max 47.2 mL·kg-1·min-1). They performed CPx and 48h and 96h later, a continuous running lasting 1 h for VT1 and until exhaustion for VT2. The results showed that EA at VT1 session, presented delta differences for VO2 (+9.1%, p = 0.125) vs. NA (+20.5%, p = 0.012). The Bland-Altman plots for VT1 presented biases of (4.4 ± 6.9) and (5.5 ± 5.6 mLO2·kg-1·min-1) for AE and NA, respectively. In VT2, the VO2 and HR of the NA showed biases of (0.4 ± 2.9 mLO2·kg-1·min-1) and (4.9 ± 4.2 bpm). The ramp protocol used in this study was inappropriate for NA because it underestimates the values of VO2 and HR at VT1 found in the rectangular load exercise. The HR showed good agreement at VT2 with CPx and may be a good parameter for controlling exercise intensity.
Social support, self-efficacy and level of physical activity of students aged 13-15 years
Authors: Campos Jhonatan Gritten , Bacil Eliane Denise Araújo , Piola Thiago Silva , Silva Michael Pereira da , Pacífico Ana Beatriz , Campos Wagner de
Published: October 2019

Abstract The aim of this study was to verify the relationship, the population attributable fraction (PAF) and the relative risk reduction (RRR) of social support and self-efficacy with level of physical activity in students. Probabilistic cross-sectional study with 1,472 students aged 13-15 years. Gender, age, social support from parents and friends, self-efficacy and levels of physical activity were evaluated through questionnaires. Data analysis was performed using Poisson regression with robust variance, PAF and RRR, adopting p≤0.05. A total of 56.1% (n = 826) of students were considered active, boys (68.7%) presenting the largest proportion. Social support from parents was positively associated with physical activity in boys (PR: 1.28, 95% CI: 1.12-1.48, PAF = 21.88) and girls (PR: 2.00; 95%CI: 1.59-2.51, PAF = 50.00). Social support from friends was positively associated with physical activity in boys (PR: 1.34, 95%CI: 1.16-1.54, PAF = 25.37) and girls (PR: 1.32, 95%CI: 1.06-1.64, PAF = 24.24). Self-efficacy was not associated with physical activity. Social support was associated with levels of physical activity, and PAF indicated that the absence of high social support from parents and friends might reduce the level of physical activity in adolescents.
Body composition and performance variables differences in female volleyball players by agegroup and playing position
Authors: Tessutti Lucas Samuel , Aguiar Samuel da Silva , Costa Gustavo De Conti Teixeira , Clemente Filipe Manuel , Lima Ricardo Franco , Neves Rodrigo Vanerson Passos , Praça Gibson Moreira , Castro Henrique de Oliveira
Published: October 2019

Abstract The aim of the present study was to evaluate the age and inter- and intra-position differences in the anthropometric variables and physical performance in young female players of Brazilian women's volleyball. Fifty-eight female volleyball players participated, divided into 3 age groups: (a) 14 and under (n=20; mean age = 12.6±0.7 years), (b) between 14 and 17 (n=31; mean age = 15.6±1.2 years), and (c) over 17 (n=7; mean age = 18.9±0.9 years). In addition, the players were also divided according to their positions: setters (n=7), opposites (n=13), passer-hitters (n=17), middle blockers (n=12) and liberos (n=9). Anthropometric characteristics, flexibility, strength / resistance abdominal muscles, pushups, explosive power of the arms, jumping abilities, shuttle run and 20-m sprint tests were evaluated. Analyses showed differences among age and playing positions for the height and bone mass (p<0.05). In the fitness assessment, no differences were found between playing positions (p>0.05). However, differences were found among for age groups horizontal jump, shuttle run and 20-m sprint, with players >17 performing better than <14 and between 14-17 years of age (p<0.05). These results demonstrated that the height, bone mass and horizontal jump, shuttle run and 20-m sprint are age dependent, while physical performance independent on the playing positions.
Comparison of maturation and physical performance in basketball athletes of different playing positions
Authors: Barazetti Lilian Keila , Varoni Pedro Rafael , Campos Fernando de Souza , Demarchi Michelli , Baumann Lucielle , Teixeira Anderson Santiago , Nunes Renan Felipe Hartmann , Flores Lucinar Jupir Forner
Published: October 2019

Abstract The aim of this study was to compare the characteristics of somatic maturation, anthropometric and physical performance (vertical jump and aerobic power) in young basketball players of different playing positions (under 13 years) and analyze these relationships using Peak Height Velocity (PHV) as a measure of somatic maturation. For this, 26 male athletes were evaluated. Anthropometric variables were: body mass, standing and sitting height, and length of lower limbs. Maturation was determined by age at PHV. Physical performance was determined by lower limb power (counter movement jump - CMJ) and aerobic power (Intermittent Recovery Test) tests. MANOVA reported significant differences (p<0.05) among playing positions regarding variables Maturity Offset, estimated PHV age, standing height, sitting height, estimated leg length, body mass and Yo-Yo IR1. In addition, it was identified that point guards reached estimated PHV at later age than their peers who act as small forwards and centers. Regarding CMJ, no significant differences were identified among playing positions, but in relation to aerobic power, point guards and small forwards presented higher performance. These findings confirm that maturation has great effect on growth and physical performance measures and the estimated PHV age is an applicable tool in young athletes, mainly aiding professionals in structuring the teaching-learning- training process in this age group.
Motor skills of children with autism spectrum disorder
Authors: Kruger Gabriele Radünz , Silveira Jennifer Rodrigues , Marques Alexandre Carriconde
Published: October 2019

Abstract The objective of this study is to describe variables of life habits associated with motor skills of children with autism spectrum disorder aged 8-10 years living in the city of Pelotas / RS. A questionnaire about lifestyle was applied and the Test of Gross Motor Development-2 (TGMD-2) was applied to assess motor skills. Independent T-test, ANOVA and Wilcoxon test were used to compare means. The study consisted of 49 individuals (42 males). The results indicate that the higher the level of ASD, the better the motor skills. Children making use of medications have greater deficits in motor skills. Higher scores on motor skills are associated with greater participation in physical education classes. Motor skills are strongly associated with independence in activities of the daily living, food, personal hygiene, dressing and bathing. The importance of the creation of PA programs aiming at improving the motor skills of this population was highlighted.