bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Profile and Course of Patients with Acute Respiratory Distress Syndrome due to COVID-19 in a Middle-Income Region in Mexico
Authors: Villalobos-Silva José Antonio , Acros-López Gladis Lucia , Velázquez-Estrada Gracia Lizbeth , Muñoz-Chavez Camilo José , Aguirre-Gómez German Antonio , Aguilera-Olvera Obed Isaí , Sánchez-González Alfredo
Published: August 2024

Introduction

COVID-19 leads to severe clinical complications that culminate in respiratory failure and acute respiratory distress syndrome (ARDS). Despite reports of some comorbidities that contribute to the development of COVID-19-mediated ARDS, there is great variation in mortality rates among critical COVID-19 patients in the world. To date, no studies have described the incidence and comorbidities associated with ARDS due to COVID-19 in the northeastern region of Mexico.

Aim of the study

To describe patients diagnosed with ARDS due to COVID-19 in the northeastern region of Mexico, as well as its variations in comparison with other regions of the country.

Material and Methods

We conducted a prospective and observational study in a tertiary care center in Northeastern Mexico. All patients diagnosed with SARS-CoV-2 infection and requiring management in the intensive care unit were included. We developed a database that was updated daily with the patients' demographic information, pre-existing diseases, disease severity, and clinical variables.

Results

The incidence of ARDS secondary to COVID-19 in HRAEV was high in comparison with other reports. Diabetes mellitus was the risk factor most associated with COVID-19-mediated ARDS.

Conclusion

Based on our findings and those previously reported in the literature, there are differences that we discuss between northeastern and central Mexico, and analyze other areas evaluated around the world.
Treinamento de força e resistência muscular para pacientes com fibromialgia: uma revisão integrativa da literatura
Authors: Carvalho Natane Moreira , Pernambuco Andrei Pereira , Soares Betânia Maria , Vilela Daniela Luzia , Faria Ellen Cristina , Lacerda Istefani Gonçalves de , Sales Izabela Diniz
Published: August 2024

Introdução: A síndrome da fibromialgia (FM) é caracterizada por dor crônica e generalizada, fadiga, depressão, cefaleia e distúrbios do sono, além de uma série de sintomas somáticos que podem interferir negativamente na qualidade de vida e funcionalidade dos pacientes com FM. Objetivo: Organizar a informação disponível acerca dos parâmetros de execução e dos efeitos do treinamento de força e resistência muscular sobre a dor, qualidade de vida e funcionalidade de pessoas com FM.  Métodos: Revisão sistemática de literatura nas bases PubMed e PeDro, foram incluídos apenas ensaios clínicos aleatorizados (ECA). Os descritores utilizados foram: “fibromyalgia and resistance training” e “fibromyalgia and strength training”. Resultados: A amostra final foi composta por 12 ECA, 646 mulheres com idade entre 18 e 65 anos. O protocolo mais utilizado foi: duas sessões semanais de 30 minutos, durante 12 semanas, com série única de 12 repetições e intensidade de 80% de 1RM. Os resultados intergrupos demonstraram que o treino de força se mostrou superior ao tratamento controle para dor em 25% dos estudos. Os participantes dos estudos apresentaram em média, uma melhora 34,2% na dor. A qualidade de vida e funcionalidade foram abordadas em 91% dos estudos. Desses, 54% apresentaram melhora significativa no desfecho. Conclusão: O treino de força e resistência muscular pode ser uma alternativa segura e viável para pacientes com FM já que pode contribuir para a melhora da dor, da qualidade de vida e da funcionalidade. Contudo a baixa qualidade metodológica da maioria dos artigos incluídos nesta revisão, prejudica a interpretação dos achados. ECA com maior rigor metodológico devem ser conduzidos a fim de esclarecer inconsistências ainda não endereçadas.
Atividade antifúngica do óleo essencial de Mentha piperita (Lamiaceae: Labiatae) – uma revisão
Authors: Rodrigues Antonio Rony da Silva Pereira
Published: August 2024

Introdução: O uso descontrolado de fúngicidas sinteticos além de provocar danos ao meio ambiente, auxiliou no aumento da resistência fúngica, uma altenativa para o controle dos fungos resistentes é o uso de fungicidas botânicos. A Mentha piperita L. (hortelã-pimenta), essa especie de hortelã possui compostos químicos como o metanol e metanona, que são descritos como agentes antifúngicos. Objetivo: Avaliar na literatura os principais autores que relatam a atividade antifúngica Mentha piperita L., frente a diferentes espécies fúngicas. Metodologia: Optou-se por realizar uma revisão de literatura nas bases de dados Scopus, Embase, Web of Science e ScienceDirect. Resultados: 12 artigos foram selecionados para compor a revisão e revelaram que o óleo essencial de hortelã-pimenta apresenta atividade fungicida frente a diversas especies fúngicas, como Cladosporium cladosporioides, Verticillium dahlia, Sclerotinia sclerotiorum, Botrytis cinérea e Aspergillus flavus, apresentando alta eficiêcia, como relatado atarvés da taxa de 72,4% para Fusarium solani. Conclusão: O óleo essencial de Mentha piperita pode ser utilzado na formulação de fungicidas botânicos.
Perfil de competências e fatores associados à prática da preceptoria em saúde: revisão integrativa
Authors: FELIPE ILANA MIRIAN ALMEIDA
Published: August 2024

Introdução: A preceptoria configura-se como uma prática educativa que permite assegurar o desenvolvimento profissional contínuo, a técnica segura, ética e eficaz do cuidado em saúde. Objetivo: Para melhor compreender os aspectos relativos ao perfil de competências e fatores associados à prática da preceptoria com foco na formação profissional em saúde, realizou-se uma revisão integrativa da literatura. Metodologia: As bases de dados foram PubMed, Epistemonikos, LILACS e SciELO, considerando os estudos publicados entre os anos de 2016 e 2022 com os descritores: preceptorship, job description, professional training, teaching-care integration services e primary health care. Resultados: Observou-se maior percentual de preceptoras jovens, entre 31 e 48 anos, com pós-graduação em nível de especialização e pouca formação pedagógica para o exercício da preceptoria. As potencialidades identificadas foram: oportunidade de desenvolvimento e aprendizagem; proatividade; motivação para o trabalho e para fornecer orientação aos novos funcionários e alunos. As fragilidades foram: falta de infraestrutura e de condições de trabalho; falta de programa de capacitação para atuar na preceptoria em saúde; falta de incentivo financeiro; sobrecarga de trabalho; déficit no processo educativo; e adversidades com a equipe de saúde. Conclusão: Existem fatores que potencializam e fragilizam a prática da preceptoria em saúde. É necessário avançar em reflexões sobre a qualificação dos preceptores à luz de novos modelos de capacitação.
Transformation of business models of companies in the field of educational technologies influenced by the introduction of artificial intelligence
Authors: PAVLYUKEVICH Evgenii D. , SADOV Konstantin S.
Published: August 2024

Subject. The study investigates elements of business models of companies in the sphere of educational technologies.
Objectives. The purpose is to determine how artificial intelligence affects product innovation, business processes, efficiency, customer relationships, and strategic development in the context of business models.
Methods. The study draws on general scientific methods of cognition.
Results. Using the Likert scale questionnaire, we collected quantitative data from managers of companies operating in the sphere under consideration. The results show the significant impact of artificial intelligence on data processing, educational process effectiveness, content creation speed, and changing roles and competencies. The findings emphasize the role of artificial intelligence in educational process optimization, automation of administrative tasks, and predictive analytics for making informed decisions. However, the impact of this technology on revenue streams and scalability remains minimal. It is essential to develop artificial intelligence-based tools, given ethical aspects, data confidentiality, and compliance with educational standards.
Conclusions. The study provides insight into strategic changes in educational technologies due to the integration of artificial intelligence, and contributes to a broader discussion about the role of technologies in education.
Power grids: Is it possible to compete with a natural monopoly?
Authors: FEDOROV Yakov P.
Published: August 2024

Subject. The article addresses financial and economic conditions and prerequisites for integration processes in the electric grid industry.
Objectives. The purpose is to reveal the financial and economic conditions and causes of integration processes in the Russian electric grid industry.
Methods. The study draws on empirical and logical constructions, analysis and synthesis, generalization, systems approach, and methods of comparative analysis.
Results. The paper identified the main financial, economic, organizational and legal aspects of integration processes in the industry. The most typical problems typical of the industry are revealed within the framework of the financial and economic analysis of the largest electric grid companies in the country.
Conclusions. The key trend in the development of the power grid industry is aimed at eliminating small companies and consolidating the industry by tightening regulatory requirements for territorial grid companies. Disadvantages of small companies include insufficient experienced staff, lack of funds for repairs and investments. Large companies are criticized for sluggishness and excessive bureaucracy, lack of motivation to reduce costs, inflated purchase prices. However, financial indicators indicate the competitiveness of small companies compared to large ones, and the competition, of course, cannot but positively affect both the quality of services and prices. Therefore, maintaining a competitive environment in the electric grid sector is a basic condition for the development of the industry, increasing customer satisfaction, and reducing price pressure.
Improving the efficiency of waste use in China's ferrous metallurgy: Strategic recommendations and optimization of decision-making tools
Authors: SU Feiyue
Published: August 2024

Subject. The article investigates prospects for improving the efficiency of waste use in the ferrous metallurgy of China.
Objectives. The purpose is to develop strategic recommendations to improve the efficiency of waste use in the Chinese ferrous metallurgy and optimize decision-making tools in this area, to analyze the applied technologies of waste processing and use.
Methods. The methodology of strategizing, developed by V.L. Kvint, a foreign member of the Russian Academy of Sciences and the methodology of industry strategizing, proposed by N.I. Sasaev, which enables to consider in detail the stages and sub-stages of industry strategizing, serve as the theoretical basis of the study.
Results. I analyzed the existing experience of developing the strategy of China's ferrous metallurgy in the context of the circular economy, considered some strategic opportunities for improving the investment decision support system in the waste management process in the ferrous metallurgy of China.
Conclusions. Strategic recommendations for improving the efficiency of waste use in the ferrous metallurgy of the People's Republic of China include the introduction of integrated waste recycling technologies in the production of ferrous metallurgy and strategic redistribution of resources from current waste use areas (scrap steel, lead) to more promising areas.
Lessons and experiences of the second period of international production in Russia
Authors: USNYAN Siranush L.
Published: August 2024

Subject. The article is devoted to Russia’s participation in global value chains and international production in the first decades of the 21st century.
Objectives. The goal is to identify trends and experience in the development of the international sector of the Russian economy, mechanisms and reasons for its emergence and development.
Methods. The study rests on a combination of general scientific and special methods of scientific knowledge, like systems and functional-structural analysis, observation, classification, statistical methods, comparison, and generalization.
Results. Rapid dynamics and tangible results of international production enabled to accumulate valuable institutional and technological experience and establish interaction. Despite globalization and WTO membership, the mechanisms of such a production were not protected from political risks and influences, which in modern conditions obviously prevail over economic interests.
Conclusions. In the context of globalization and specifics of the Russian economy, international production cannot be replaced by “import substitution”. Therefore, when developing a new stage virtually from scratch, it is necessary to take into account the experience and lessons of the stage that has just been accomplished.
The single supranational BRICS digital currency as a factor of independence from the dollar-centric international financial system
Authors: ANOSOV Evgenii D.
Published: August 2024

Subject. The research explores the way of creating an independent interregional financial profile for BRICS+ countries, linked by a single supranational digital currency of central banks.
Objectives. The aim is to underpin the realistic existence of alternative model of the supranational financial regulation with its own international currency unit as a factor of independence from the payment and settlement infrastructure of unfriendly countries.
Methods. The study employs general scientific methods of systems approach, analogies, historical and logical analysis.
Results. The paper justifies the feasibility of the proposed method of creation and sustainable functioning of the supranational currency unit within the BRICS+, which is based on the avowed theoretical elaborations and practical experience of the existing international monetary system (IMS). The findings can be used to design an alternative to the dollar-centric standard model of IMS functioning with its own transcontinental currency.
Conclusion. The proposed IMS model will serve as a methodological basis for monetary authorities of countries that seek to develop their financial sovereignty, which enables the sustainable cross-country integration within the BRICS, and strengthens their economic relations with no influence of unfriendly countries.
Desenvolvimento de impermeabilizante à base de Poliestireno expandido
Authors: Hertel Lorena Rocha , Ferrari Matheus , D'Amelio Monica Tais Siqueira
Published: August 2024

O descarte consciente, reaproveitando, reutilizando e reciclando todo o tipo de material tem se tornado evidente no cenário atual. O Poliestireno expandido, conhecido como Isopor®, é um dos materiais presentes em todos os meios, sendo produzidas em média 336 mil toneladas por ano no Brasil. Devido ao descarte excessivo, o qual ocupa muito espaço, sugeriu-se transformá-lo em um novo produto. Este trabalho apresenta o desenvolvimento de um impermeabilizante à base de poliestireno expandido e um solvente de baixa toxicidade e custo, a ser aplicado em diferentes materiais da construção civil. Foram testados quatro solventes orgânicos (limoneno, acetato de etila, terenbetina e acetona) e realizados testes de solubilidade, análise do tempo de secagem, teste de absorção, análise de ângulo de contato e de poros. Os resultados mostraram que o impermeabilizante desenvolvido com o acetato de etila junto com o poliestireno expandido proporcionaram uma redução na umidade, formando uma camada protetora no material resultando no sucesso da impermeabilização em diversos tipos de materiais.
Formulation and Evaluation of Bilayer Matrix Tablet of Vildagliptin and Acarbose
Authors: Jain Ruchi , Jain Surendra Kumar
Published: August 2024

Our investigation aimed to formulate a bilayer matrix tablet that includes Vildagliptin as a component for prolonged release and acarbose for immediate release. Treatment with these medications provides a high standard of living for individuals afflicted with type II diabetes mellitus. This medicine offers several key benefits, including its precise targeting of specific actions, exceptional safety, and outstanding effectiveness.  Acarbose was immediately formulated with super disintegrants, specifically sodium starch glycolate (SSG) and croscarmellose sodium (CCS). The tablet was then compressed via direct compression. Sustained release layer of vildagliptin was prepared utilizing HPMCK100 as release retarding polymers. The wet granulation technique was employed, and PVP K30 in IPA solution (10%) was used as a granulating agent. The bilayer tablet underwent evaluation for several characteristics, including hardness, friability, weight variation, percentage of medication content, percentage of medication release study, and disintegration time of IR layer. An optimization process was used to refine a formulation, resulting in a formulation that contains 12 mg of CCS and 32 mg of HPMC K100M. Optimized formulation shows 98.3±1.05% immediate release and 34.54±1.54%, 69.32±1.60% and 96.75±2.13% drug release at 1, 4 and 8 hours, respectively. Our study revealed that bilayer tablets including Vildagliptin and Acarbose might be a superior alternative to standard dosage forms.
Pulsatile Drug Delivery Systems of Esomeprazole for Improved Therapeutic Efficiency: In-vivo Bioavailability Study and In-vitro In-vivo Correlation
Authors: Kurapati Phaneendra , Chinni Santhivardhan
Published: August 2024

The prime objective was development and pharmacokinetic characterization of pulsatile drug delivery systems (PDDS) to gain chronomodulated delivery of Esomeprazole (EMP) suitable for combating nocturnal acid breakthrough (NAB). Analytical method by HPLC was developed for the quantification of EMP from the biological samples. In vivo bioavailability testing was accomplished on Sprague–Dawley rats for the developed PDDS formulation. In-vitro in-vivo correlation (IVIVC) was carried out by deconvolution method. The bioanalytical approach that was developed exhibited linearity within the range of 100-2000ng/mL with correlation coefficient of 0.999. The results of other method validation parameters were found satisfactory. The in-vivo studies on the PDDS specified that the EMP was released as two pulses at the desired times. The AUC and MRT from the PDDS were found to be increased by 3.02 times and 2.2 times respectively in comparison with the marketed formulation. IVIVC revealed that considerably good correlation was observed. The established bioanalytical approach proved to be appropriate for quantifying EMP in biological samples. The developed PDDS formulation of EMP was effective to combat the NAB condition.
Unveiling the Pharmacological Spectrum of Justicia gendarussa: A Comprehensive Review
Authors: Sontakke Pornima A , Patil Vaishnavi P , Wankhade Pavankumar P , Vhyawahare Niraj S
Published: August 2024

Justicia gendarussa Burm. f (J. gendarussa) is a flora part of Acanthaceae family, is a herbal remedy localized to numerous regions of Asia, which has been used since ancient times for its traditionally claimed pharmacological activities. J. gendarussa is a fast-developing bush that discovered in the tropical shady and moist places. Mostly this plant is found in China, hence also known as Chinese medicinal plant. Over the past few years, it has gathered significant attention due to its diverse pharmacological activities and rich chemical composition. Pharmacological investigations have revealed that J. gendarussa possesses a broad spectrum of biological activities, comprising, although not restricted to anti-HIV, anti-inflammatory, analgesic, anxiolytic, anti-microbial, hepatoprotective, anti-fungal, antioxidant, larvicidal, anthelmintic and antiarthritic. Furthermore, chemical analyses of J. gendarussa have identified a wide array of bioactive constituents, like alkaloids, flavonoids, terpenoids, phenols, carbohydrates and fatty acids. These phytochemicals play pivotal roles in mediating the observed pharmacological activities and hold promise for the creation of novel medications or supplements targeting the various health conditions. This review focuses on the pharmacological profile, bioactive components, and ethanobotanical significance of J. gendarussa. This inclusive assessment provides an extensive study of the current state of research on J. gendarussa, encompassing its pharmacological effects and chemical constituents. By consolidating existing knowledge, scholars and practitioners alike can benefit greatly from this review, fostering advanced exploration of this remarkable plant species for therapeutic purpose.
From Traditional Practices to Modern Interventions: Exploring Herbs Role in Treating Liver Cancer Following Its Signalling Pathways
Authors: Deore Manswi R , Shirode Devendra S , Patil Vaishnavi P , Rajput Gunjansing
Published: August 2024

The foremost hepatocellular carcinoma is a primary reason for cancer-causing death globally. It ranks as the second main factor in male cancer-related mortality and the fourth nearly prevalent neoplasm overall. Compared to women, men are more likely to acquire hepatoma. Many risk factors have been related to liver cancer which include Cirrhosis, NAFLD, NASH, viral hepatitis, Intake of Alcohol, Aflatoxins, Obesity & Diabetes, Iron overload, Tobacco use, Exposure to certain chemicals, Family history, etc. Any chronic inflammatory liver disease can cause HCC, but cirrhosis is the pathophysiological process that is present in cases of the disease. There are several treatments approaches available for hepatocellular carcinoma (HCC), including surgery, immunotherapy, liver transplantation, and chemotherapy. However, these treatments have not significantly improved outcomes for HCC patients. An herbal medicine containing natural compounds has become a viable therapeutic choice for various diseases, including cancer. Among these, some herbal components are interested in treating HCC. All these below-mentioned plants have anticancer properties. They work against cancer cells through various pathways and are responsible for apoptosis, Antiproliferation, cytotoxicity, etc. All this study has been conducted on multiple cell lines in vitro studies. Herbal medicine is often more affordable and accessible than conventional cancer treatments, particularly in regions where access to healthcare is limited. Growing attention has been shown in researching and developing herbal medication used to treat cancer, leading to the discovery of new compounds and formulations with potential therapeutic benefits. In this aspect, we are highlighting various expected pathways to cure HCC.
A epidemia dos transtornos alimentares
Authors: Appolinário José Carlos  Borges , Nunes Maria Angélica Antunes
Published: August 2024

Os transtornos alimentares têm crescido de forma alarmante, principalmente entre os jovens. Segundo dados da Associação Médica Norte-Americana, 22,36% das crianças e dos adolescentes de 6 a 18 anos apresentam condições como anorexia, compulsão alimentar e bulimia, entre outros, ou uma combinação delas. Em todo o mundo, segundo a Organização World Eating Disorder, mais de 70 milhões de pessoas são afetadas por algum transtorno alimentar, cujos tipos mais comuns são anorexia nervosa, bulimia nervosa e transtorno da compulsão alimentar.
Para falar sobre o assunto, o ABP TV de hoje, dia 23 de julho de 2024, recebe os psiquiatras José Carlos Appolinário e Maria Angélica Antunes Nunes.
Apresentação: Lucas Veloso
Transmissão ao vivo: RecPlay Produtora
Produção: Departamento de Comunicação da ABP
Realização: Associação Brasileira de Psiquiatria - ABP
Prediksi Burnout Pada Programmer Menggunakan Teknik Pengenalan Pola Untuk Identifikasi Dini Dan Intervensi
Authors: Saputra Candra Heru , Hermawan Arief , Avianto Donny
Published: August 2024

Burnout atau kelelahan kerja merupakan sebuah fenomena yang sering dihadapi oleh profesional dalam berbagai bidang, termasuk programmer. Dampak negatif dari burnout mencakup penurunan kesejahteraan individu dan produktivitas kerja. Penelitian ini berkontribusi pada subjek penelitian dengan mengembangkan sebuah model prediktif yang inovatif untuk identifikasi dini dan intervensi burnout pada programmer menggunakan teknik pengenalan pola. Originalitas penelitian ini terletak pada penerapan teknik pengenalan pola secara khusus pada populasi programmer, yang belum banyak dieksplorasi dalam literatur sebelumnya. Data yang digunakan dalam penelitian ini diperoleh dari kuesioner yang mencakup pertanyaan terkait pola kerja, kebiasaan individu, dan indikator burnout berdasarkan kriteria Maslach Burnout Inventory (MBI). Metodologi yang diterapkan melibatkan pengumpulan dan pra-pemrosesan data, ekstraksi fitur, dan aplikasi algoritma pengenalan pola untuk konstruksi model. Hasil penelitian menunjukkan bahwa model yang dikembangkan mampu mengidentifikasi risiko burnout dengan akurasi yang tinggi. Teknik pengenalan pola terbukti efektif dalam menggali pola dan insight yang relevan untuk identifikasi dan intervensi burnout pada programmer, sehingga dapat memberikan kontribusi signifikan dalam pemahaman dan pencegahan burnout di kalangan programmer. Penelitian ini diharapkan dapat digunakan sebagai referensi dalam praktik dan penelitian lebih lanjut.
 
Abstract
Burnout is a phenomenon frequently encountered by professionals across various fields, including programmers. The negative impacts of burnout include reduced individual well-being and decreased work productivity. This study contributes to the subject by developing an innovative predictive model for early identification and intervention of burnout in programmers using pattern recognition techniques. The originality of this research lies in the application of pattern recognition techniques specifically to the programmer population, which has not been extensively explored in previous literature. The data used in this study were obtained from questionnaires that included questions related to work patterns, individual habits, and burnout indicators based on the Maslach Burnout Inventory (MBI) criteria. The methodology involved data collection and preprocessing, feature extraction, and the application of pattern recognition algorithms for model construction. The results indicate that the developed model is capable of identifying burnout risk with high accuracy. Pattern recognition techniques proved effective in uncovering relevant patterns and insights for the identification and intervention of burnout in programmers, thereby making a significant contribution to the understanding and prevention of burnout among programmers. This study is expected to serve as a reference in both practice and further research.
Fatores que influenciam o rebaixamento cognitivo de pessoas idosas
Authors: Santos Fernanda Sampaio , Souza João Pedro Mendes de , Gomes Natállia Gabriela Silva , Silva Ariadne Cruvinel , Carvalho Bruna Marra de , Silva Constanza Thaise Xavier , Moura Léa Resende
Published: August 2024

Objetivo: Identificar os fatores que influenciam o rebaixamento cognitivo das pessoas idosas. Métodos: Trata-se de uma revisão integrativa da literatura, com artigos publicados entre 2019 e 2022. Utilizou-se como questão norteadora: “Quais são os fatores que influenciam o rebaixamento cognitivo das pessoas idosas? ”. A pesquisa bibliográfica foi realizada nas bases de dados Publisher Medline (PubMed), Scientific Electronic Library Online (SCIELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), por meio dos Descritores em Ciências da Saúde (DECS): Cognição, Fatores Protetores, Fatores de Risco, Saúde do Idoso e operador booleano “AND”. Resultado: Os mecanismos envolvidos no rebaixamento cognitivo são orientados por três eixos: hábitos de vida, escolaridade e saúde mental, ressaltando-se entre eles os fatores de proteção e os de potencialização do declínio. Portanto, idosos com laços sociais fortificados, maiores níveis de escolaridade, integrados à sociedade por meio do lazer e uso de internet, prática de hábitos de vida saudáveis e ausência de distúrbios psíquicos apresentam melhor desempenho cognitivo. Entretanto, cada fator prejudicial adicionado, acentua proporcionalmente o rebaixamento cognitivo. Conclusão: Os fatores que rebaixam a cognição de idosos atuam de forma sinérgica e estão relacionados com as condições sociais e culturais da população idosa.
Os indicadores da eficiência na doação de órgãos sólidos por morte encefálica
Authors: Ramalho Maria Eduarda Motta , Duarte Tallita Lougon , Silveira Lucas Zappa Monte Lima , Grunewald Tatiana Mara dos Santos Azevedo , Marins Nina Cavalcanti Trindade , Rocha Mirelli Katzuk de Carvalho , Cunha Gabriela de Oliveira , Santana Tainah de Souza , Rodrigues Lais de Souza , Rodrigues Maria Aparecida de Almeida Souza
Published: August 2024

Objetivo: Investigar os indicadores de eficiência no transplante de órgãos de um doador com morte encefálica e os fatores que podem influenciar e comprometer a doação desses órgãos sólidos. Revisão Bibliográfica: O transplante de órgãos é uma técnica cirúrgica crucial para substituir órgãos afetados por doenças graves, proporcionando uma segunda chance de vida para receptores em falência orgânica. Pode ser realizado com órgãos provenientes de doadores vivos ou falecidos, este último muitas vezes diagnosticado com morte encefálica. Entretanto, é importante ressaltar que questões como eficácia e eficiência são relevantes. A eficiência é determinada pela relação entre os recursos utilizados e o número de transplantes realizados, além da taxa de sobrevivência. No entanto, a recusa familiar pode ser um obstáculo significativo para a doação de órgãos, influenciada por fatores culturais, religiosos e de comunicação. Considerações finais: Apesar dos avanços, ainda há desafios a serem superados para melhorar a eficácia do processo de transplante, destacando-se a importância de investigar os indicadores de eficiência e os fatores que impactam a doação de órgãos.
Disfunção erétil pós infecção COVID-19
Authors: Silva Diana Karla de Mesquita , Santos Kaue Silva Aguiar dos , Muniz Monique Nayara Coelho , Dias Filho Carlos Alberto Alves
Published: August 2024

Objetivo: Investigar a relação entre disfunção erétil (DE) e COVID-19, examinando estudos relevantes. Métodos: Trata-se de uma revisão integrativa referente à relação entre disfunção erétil (DE) e COVID-19 conduzida no período entre os anos de 2021 e 2024, utilizando as bases de dados LILACS e MEDLINE, os Descritores em Ciências da Saúde (DeCS) "Disfunção erétil", "Infecção" e "COVID-19". Resultados: Foram selecionados 13 artigos para análise. Os estudos revisados apresentam evidências de uma associação significativa entre COVID-19 e disfunção erétil, danos ao músculo liso cavernoso, aumentando a prevalência de disfunção erétil, mesmo pós infecções leves, disfunção endotelial, a carga psicológica e a diminuição dos níveis hormonais induzida pela COVID-19. Considerações finais: A relação entre COVID-19 e disfunção erétil é complexa e multifatorial, envolvendo fatores hormonais, psicológicos, vasculares, bem como, fatores de risco e os mecanismos subjacentes. O diagnóstico precoce, análise dos fatores ambientais e o acompanhamento psicológico pós-infecção são fundamentais para mitigar os efeitos adversos na função sexual masculina.
Desafios da telenfermagem durante pesquisa de orientações de exames de colonoscopia
Authors: Vasconcelos Andréa Paula Dourado , Andrade César Augusto Souza de , Freitas Lúcia de Fátima Nunes , Campos  Filho Amadeu Sá de , Araújo Ana Paula Ferreira Marques de
Published: August 2024

Objetivo: Analisar as dificuldades encontradas durante as consultas por Telenfermagem realizadas por Enfermeiras nas orientações dos exames de colonoscopias em uma unidade de endoscopia de um Hospital Universitário de Recife - PE. Métodos: Trata-se de um estudo transversal, abordagem quantitativa. A população é composta por 164 pacientes que foram convidados a participar da pesquisa e foram submetidos ao exame de colonoscopia pela primeira vez. Os dados foram coletados a partir de laudos dos exames e das orientações dadas por teleconsultas, no período de julho a outubro de 2023, tabulados em planilha Excel e avaliados através de gráficos. Resultados: Durante as teleconsultas realizadas foram apontadas várias dificuldades e desafios para realização das mesmas, das 66 teleconsultas realizadas (6,3 %) foi realizada por chat, (4,7 %) por chamada de vídeo através do WhatsApp, e (79,7 %) por teleconsulta sem dificuldades. Conclusão: Pode-se observar que mesmo diante das dificuldades, a tecnologia, foi uma grande aliada para encontrar soluções e contornar os desafios, mesmo havendo limitações, foi possível fazer com que o serviço de orientações não parasse e fosse dado continuidade a assistência aos pacientes.
Mortalidade materna em uma maternidade para gestação de alto risco de uma cidade do estado da Bahia
Authors: Silveira Marcia Maria Pedreira da , Santos Iris Rodrigues dos , Silva Gabriela de Cerqueira , Moraes Marcia Maria dos Santos de
Published: August 2024

Objetivo: Descrever os óbitos maternos ocorridos em maternidade de gestação de alto risco de uma cidade do estado da Bahia. Métodos: Estudo observacional e descritivo que analisou, entre 2015 e 2021, as fichas de investigação hospitalar de óbito materno. Mulheres, no ciclo gravídico-puerperal, que não faleceram por causas externas e cujo óbito ocorreu após 24h de internação foram incluídas. Avaliaram-se as características sociodemográficas e gestacional, o diagnóstico na internação, estado gestacional no óbito e causas morte. Utilizou-se estatística descritiva para análise. Estudo aprovado por Comitê de Ética em Pesquisa. Resultados: 131 óbitos maternos foram incluídos e 40,5% ocorreram entre 24h e 48h. As mulheres tinham em média 30 anos, eram pardas e pretas (89,3%) e solteiras (52,7%). Na internação, 60,3% estavam gestantes, 33,6% puérperas e 4,6% em abortamento; e a maioria sem doença gestacional, mas com cardiopatia (13%), hipertensão arterial sistêmica (12,2%) e anemia falciforme (11,5%) como principais doenças preexistentes. Motivaram a internação as infecções (30,5%), distúrbios hipertensivos (24,4%) e hemorragia (14,5%); e as principais causas de óbito foram infecção (38,9%), hemorragias (20,6%) e distúrbios hipertensivos (18,4%). Conclusão: Este estudo identificou mulheres que correspondem ao principal grupo de risco para morte materna evitável e sinaliza as fragilidades no acesso aos serviços de saúde materna qualificados.
Inadvertent iatrogenic splenic vein occlusion resulting in sinistral portal hypertension and massive gastric variceal hemorrhage
Authors: Unteriner Jackson George , Assael Dylan , Giardina Joseph Daniel
Published: August 2024

A 27-year-old man with history of Budd–Chiari syndrome complicated by portal hypertension presented to an outside hospital with melena and hematemesis. He underwent direct intrahepatic portocaval shunt (DIPS) placement and variceal embolization. Eleven months later, the patient presented to the authors’ institution with recurrent upper gastrointestinal bleeding. DIPS venogram demonstrated a patent stent-graft; however, it also revealed plug occlusion of the splenic vein, inadvertently performed at the time of initial DIPS procedure. Interrupted splenic venous flow gave rise to sinistral portal hypertension, which, in turn, led to exacerbation of gastric varices and development of a massive gastrorenal shunt. Splenic artery embolization and a balloon-occluded retrograde transvenous obliteration were performed, resulting in resolution of gastrointestinal hemorrhage.
Efficacy of Regional Citrate versus Heparin Anticoagulation in Continuous Renal Replacement Therapy
Authors: Bhandari Gaurav , Choudhury Debarun , Bhalla Anil Kumar , Malik Manish , Gupta Anurag , Bhargava Vinant , Tiwari Vaibhav , Chadha Shiv , Gupta Ashwani , Rana Devinder Singh
Published: August 2024

Background

Continuous renal replacement therapy (CRRT) is used in hemodynamically unstable patients with acute kidney injury (AKI). Heparin, the most commonly used anticoagulant, has a significant bleeding risk and is associated with heparin-induced thrombocytopenia. Regional citrate anticoagulation is an alternative anticoagulation strategy in CRRT.

Materials and Methods

A randomized controlled trial was conducted in the Intensive Care Unit over one year, from October 2020 to September 2021, in patients with AKI requiring CRRT. Fifty-two patients were randomized into two groups: group 1 received regional citrate anticoagulation, and group 2 received heparin anticoagulation.

Results

The mean age in group 1 was 50.46 years, while it was 49.35 years in group 2. The mean filter lifespan in group 1 was 45.11 hours, while in group 2, it was 26.11 hours and was statistically significant (P < 0.001). The mean effective delivered RRT dose was higher in group 1 (26 ml/kg/hour) compared to group 2 (24.23 ml/kg/hour), which was statistically significant (P < 0.001). Bleeding episodes were higher in group 2 than in group 1 (42.3% vs 11.5%), which was statistically significant (P = 0.027). The RCA group had various electrolyte and metabolic complications, but these were not statistically significant.

Conclusion

Regional citrate anticoagulation is better than heparin anticoagulation in terms of filter lifespan, effective delivered RRT dose, bleeding episodes, and metabolic complications.
From Water to Blood: Cupriavidus pauculus Bacteremia in a Hemodialysis Patient
Authors: Saha Anish Kumar , Das Padma , Rathore Vinay , Badge Rohit , Pathak Naman Mahesh
Published: August 2024

Cupriavidus pauculus is a gram-negative rod isolated from water. It is rarely known to cause infections in humans. We present the case of a 72-year-old lady who developed Cupriavidus pauculus bacteremia probably originating from the water treatment plant of a hemodialysis unit. The patient improved with timely treatment with appropriate antibiotics.
Internal quality assurance cell as a “think tank:” Taking initiative!
Authors: Avinash Bhagyalakshmi
Published: August 2024

Quality in higher education is the key to stepping up the ladder for being among the top, be it accreditation, ranking, admissions, etc. But how do we achieve the highest quality is a challenge. The internal quality assurance cell (IQAC) makes an institute work harder, guiding its institute to take an efficient pathway and achieve success. The vision and mission of IQAC is to achieve and maintain excellence in academics, administration, research, teaching, extracurricular activities, and community work. This article focuses on the important role that the IQAC plays in guiding the institutes and universities to achieve excellence.
Food habits and lifestyle of Indian medical students’ study at Jiamusi University: A questionnaire-based study
Authors: Mukhida Sahjid , Mali Vikrambhai , Riji Bimcle , Shingadiya Paras , Li Mei Xui
Published: August 2024

Objectives:

Dietary habits depend on the environment, the country, and the community. Changes have the potential to endanger people’s health. There will be some dietary-related health issues when traveling. Many Indian students pursue medical studies overseas. A student begins to acclimate to the climate after moving to a new place. In an unfamiliar culture, they alter their way of life, particularly their eating patterns. Understanding the relationship between eating habits and appendicitis in Indian medical students at Jiamusi University in China was the primary goal of the study.

Material and Methods:

A questionnaire was prepared in consultation with students who have undergone appendectomy within the past 6 months which included students’ infographic details, dietary habits in their home, lifestyles, exercise, past illness regarding appendicitis, and adoption of the new lifestyle.

Results:

In all, 627 medical students from India were included in the study. About 36% of the pupils were female, while 64% of the students were male. In China, just 36% of students continued to follow a vegetarian diet, despite 58% of students being vegetarians at home. Just 61% of students were happy with the food that they were eating, and 82% of students were preparing meals for themselves. Although just 6% of students required hospitalization, over 26% of students experienced difficulties as a result of stomach issues.

Conclusion:

A rapid shift in diet from vegetarian to non-vegetarian foods can result in appendicitis or other serious gastrointestinal illnesses. Students may prevent appendicitis and other illnesses by continuing to lead a healthy lifestyle.
БЭК – ОФИС ВЕБПОРТАЛА «ИПС КОНИ – 3», ВЕРСИЯ 1
Authors: Зайцев А.М.
Published: August 2024

Программа предназначена для управления работой веб-портала «ИПС КОНИ-3» версии 2010-2019 годов. С помощью программы контролируется информация о пользователях поисковой системы, оказанных услугах в зависимости от выбранного тарифа, их стоимости и условий. При помощи программы выставляются рекламные баннеры с подсчетом просмотров и показов, собирается статистика посещения, проводится анализ посещения веб-портала и сбор сетевой информации. Функционал анализа полученной сетевой статистики показывает, какие пользователи просматривали веб-портал, из каких регионов мира и с помощью каких браузеров. Функционал программы для связи с пользователями позволяет отправку сообщений одному пользователю, группе пользователей или всем пользователям. Функционал программы автоматического перевода на другие языки позволяет переводить интерфейс на английский язык нажатием одной кнопки. Функционал «Биллинг» контролирует все этапы оплаты и зачисления средств на счет пользователя от выписки счета до списания за услуги. Тип ЭВМ: веб-сервер; ОС: Windows Server 2008–2012 или Linux.
БЭК – ОФИС ВЕБПОРТАЛА «ИПС КОНИ – 3» С СИСТЕМОЙ БИЛЛИНГА, ВЕРСИЯ 2
Authors: Зайцев А.М.
Published: August 2024

Программа предназначена для управления работой веб-портала «ИПС КОНИ-3» версии 2019-2020 годов. Программа управляет новой версией веб-портала «ИПС КОНИ-3», запущенной в 2019 году. С помощью программы производится менеджмент внутренней информации веб-портала, мониторится работа веб-портала в режиме онлайн. Анализируются данные о пользователях, оказанных услугах, количестве подключений и объеме просмотренной информации. При помощи программы производится визуализация данных в реальном времени и наложение их на карту сервиса Яндекс-карты. Все статистические данные привязаны к регионам и автоматически обновляются в режиме реального времени. Новым функционалом программы является система отображения результатов испытаний рысистых лошадей с указанием всех параметров заездов. Получение данных об испытаниях рысистых и скаковых лошадях идет по двум каналам: ИАС «Ипподомы»; ИПС – «КОНИ-3» ВНИИ Коневодства. Вся информация представлена на двух языках, русском и английском. Перевод на другой язык осуществляется автоматически. Тип ЭВМ: веб-сервер; ОС: Windows Server 2008–2012 или Linux.
ПОТЕНЦИАЛ СОВЕРШЕНСТВОВАНИЯ И РАЗВИТИЯ УСЛОВИЙ ФУНКЦИОНИРОВАНИЯ ТЕХНОПАРКОВ
Authors: Каирова Ф.А. , Датиева А.А.
Published: August 2024

Работа посвящена изучению вопросов создания, структурирования деятельности технопарков, а также выявлению проблем, с которыми сталкиваются технопарки на протяжении всего пути развития. Исследованы особенности функционирования и развития технопарков в Российской Федерации, проведен сравнительный анализ показателей деятельности действующих технопарков. В процессе проведения исследовательского анализа деятельности технопарков, было выявлено, что необходимо совершенствовать систему оценивания показателей работы технопарков, так как на сегодняшний день, отсутствуют критерии, на основе которых можно было бы проводить полный и постоянный сравнительный анализ.
НАЛОГ НА ДОБАВЛЕННУЮ СТОИМОСТЬ (НДС) ПРИ АУДИТЕ НАЛОГООБЛОЖЕНИЯ В СТРОИТЕЛЬНЫХ КОМПАНИЯХ
Authors: Каширская Л.В. , Комушева А.Ц. , Зурнаджьянц Ю.А.
Published: August 2024

Статья рассматривает важность аудиторской проверки НДС в строительных компаниях для обеспечения соблюдения налоговых требований и предотвращения возможных нарушений. В ходе аудита проводится проверка документации, связанной с НДС, анализируется правильность расчета и уплаты налога, проверяется наличие и правильность заполнения налоговой отчетности и анализируются операции, связанные с НДС.
ОЦЕНКА СТОИМОСТИ ПРЕДПРИЯТИЯ ДОХОДНЫМ ПОДХОДОМ И ВЫЯВЛЕНИЕ НАПРАВЛЕНИЙ ЕЕ ПОВЫШЕНИЯ
Authors: Климова Е.З. , Павлова И.А. , Макушева Ю.А.
Published: August 2024

Оценка стоимости предприятия является важным инструментом для принятия решений в бизнесе, так как может быть использована при определении реального потенциала предприятия, его производственных возможностей, а также для обеспечения эффективности функционирования и конкурентоспособности. Оценка стоимости предприятия может включать анализ управления компанией, структуры ее капитала, перспектив ее будущей прибыли и рыночной стоимости ее активов. Это процесс определения стоимости предприятия на основе различных подходов и методов, включая доходный, рыночный и сравнительный. В статье представлена оценка стоимости предприятия ПАО «ГМК «Норильский никель» доходным подходом с использованием метода дисконтирования денежных потоков и выявлены направления для повышения рыночной стоимости предприятия.
ЭКОНОМЕТРИЧЕСКИЙ АНАЛИЗ ВЕЛИЧИНЫ ВАЛОВЫХ СБЕРЕЖЕНИЙ В СОЕДИНЕННЫХ ШТАТАХ АМЕРИКИ
Authors: Козлов Д.Д. , Трегуб И.В.
Published: August 2024

Обширный анализ валовых сбережений в Соединенных Штатах Америки. Рассматривается этот важный экономический показатель в контексте макроэкономических и социальных аспектов. Исследование охватывает временной период исследования (1970–2021 гг.), ключевые переменные, влияющие на валовые сбережения, и их роль в экономическом развитии страны. Выявление и критический анализ факторов, влияющих на динамику валовых сбережений в США. В статье рассматривается как макроэкономические показатели, такие как национальный доход, государственные расходы, уровень инфляции, рост населения и реальная процентная ставка и в какой степени, взаимосвязаны с уровнем сбережений. Для достижения поставленной цели используется эконометрическая модель, включая регрессионный анализ (динамический и статический), используется база данных Всемирного банка и текущие тренды. Будут проанализированы доступные данные о валовых сбережениях и коррелирующих факторах за определенный временной период, чтобы выявить структурные зависимости и влияние различных переменных. В данной статье рассмотрена эконометрическая модель, которая привела к выявлению значительного воздействия уровня национальных доходов и государственных расходов на валовые сбережения в США. Также, тестирование модели показало, что модель адекватна и применима для дальнейшего анализа динамики валовых сбережений в США. Наши результаты подтверждают важность макроэкономических факторов в определении валовых сбережений в Америке. Понимание этих взаимосвязей имеет критическое значение для разработки экономической политики, направленной на стимулирование сбережений и устойчивое экономическое развитие страны.
ИМПОРТОЗАМЕЩЕНИЕ В ФАРМИНИНДУСТРИИ РФ
Authors: Батрасова А.Д. , Коновалова Т.В. , Комаров П.И.
Published: August 2024

Актуальность статьи определяется важностью фармацевтической отрасли с точки зрения обеспечения национальной лекарственной безопасности РФ в условиях санкций. Проведенный анализ показывает, что различные инструменты поддержки отрасли, применяемые, в частности, в рамках реализации программы «Фарма – 2020» дали свои положительные результаты. Оценка эффективности инновационной деятельности методам DEA показала, что отрасли имеют единичную инновационную эффективность, более того они эффективно в смысле Паретто-Кумпанса. Сравнение импорта и экспорта лекарственных препаратов показало, что можно говорить о смешанной модели импортозамещения, но говорить о полноценном импортозамещении как по объему, так и номенклатуре лекарственных препаратов еще рано.