bluuebunny/crossref_metadata_2025 huggingface dataset:
Horse Innate Immunity in the Control of Equine Infectious Anemia Virus Infection: A Preliminary Study
Authors: Cardeti Giusy , Manna Giuseppe , Cersini Antonella , Nardini Roberto , Rosati Sergio , Reina Ramses , Cittadini Marina , Sittinieri Stefania , Altigeri Alessia , Marcario Gaetana Anita , Scicluna Maria Teresa
Published: November 2024

The mechanisms of the innate immunity control of equine infectious anemia virus in horses are not yet widely described. Equine monocytes isolated from the peripheral blood of three Equine infectious anemia (EIA) seronegative horses were differentiated in vitro into macrophages that gave rise to mixed cell populations morphologically referable to M1 and M2 phenotypes. The addition of two equine recombinant cytokines and two EIA virus reference strains, Miami and Wyoming, induced a more specific cell differentiation, and as for other species, IFNγ and IL4 stimulation polarized horse macrophages respectively towards the M1 and the M2 phenotypes. Infection with EIAV reference strains resulted in a morphological transformation of macrophages compatible with the M1 differentiation pattern. All samples were also analyzed by molecular analyses for equine herpesviruses that could have acted as an interference and were found to be negative. The mRNA expression level of the pro-inflammatory genes MMP13 and IL6 in treated equine monocyte-derived macrophages (eMDMs) was evaluated by a SYBR® Green real-time PCR. In this study, MMP13 represented a reliable target gene to evaluate pro-inflammatory status of macrophages in horses because IFNγ and EIAV infection considerably increased its expression. A more in-depth study of the expression genes of both cytokine-induced and virus-induced markers of eMDM polarization may help us to understand whether these markers in horses are the same as those found in other animal species with similar pathways of innate immunity activation. The identified markers of each macrophage population would allow analysis of the differentiation profiles that could provide information on virus infectivity control in equid populations, envisioning their use in therapeutic strategies.
The Known and Unknown of Global Tick-Borne Viruses
Authors: Moming Abulimiti , Bai Yuan , Wang Jun , Zhang Yanfang , Tang Shuang , Fan Zhaojun , Deng Fei , Shen Shu
Published: November 2024

Ticks are crucial vectors for various pathogens associated with human and animal diseases, including viruses. Nevertheless, significant knowledge gaps prevail in our understanding of tick-borne viruses (TBVs). We here examined existing studies on TBVs, uncovering 870 documented virus species across 28 orders, 55 families, and 66 genera. The discovery history, vector ticks, and hosts of TBVs, as well as the clinical characteristics of TBV-induced diseases, are summarized. In total, 176 tick species from nine tick genera were confirmed as vectors for TBVs. Overall, 105 TBVs were associated with infection or exposure to humans and animals. Of them, at least 40 were identified to cause human or animal diseases. This review addresses the current challenges associated with TBV research, including the lack of knowledge about the identification of novel and emerging TBVs, the spillover potentials from ticks to hosts, and the pathogenicity and infection mechanisms of TBVs. It is expected to provide crucial insights and references for future studies in this field, while specifically focusing on expanding surveys, improving TBV identification and isolation, and enhancing the understanding of TBV–vector–host interactions. All of these findings will facilitate the preparation for preventing and treating diseases caused by emerging and novel TBVs.
Modulation of Monocyte Effector Functions and Gene Expression by Human Cytomegalovirus Infection
Authors: Planchon Matthew S. , Fishman Jay A. , El Khoury Joseph
Published: November 2024

Monocytes are crucial players in innate immunity. The human cytomegalovirus (CMV) infection has significant impacts on monocyte effector functions and gene expression. CMV, a β-herpesvirus, disrupts key monocyte roles, including phagocytosis, antigen presentation, cytokine production, and migration, impairing their ability to combat pathogens and activate adaptive immune responses. CMV modulates monocyte gene expression, decreasing their capacity for antigen presentation and phagocytosis while increasing pro-inflammatory cytokine production, which can contribute to tissue damage and chronic inflammation. CMV also alters monocyte migration to sites of infection while promoting trans-endothelial migration, thus aiding viral dissemination. Additionally, the virus affects reactive oxygen species (ROS) production, thereby contributing to end-organ disease associated with CMV infection. Overall, these changes enhance viral persistence during acute infection and facilitate immune evasion during latency. We highlight the clinical significance of these disruptions, particularly in immunocompromised patients such as transplant recipients, where the modulation of monocyte function by CMV exacerbates risks for infection, inflammation, and graft rejection. An understanding of these mechanisms will inform therapeutic strategies to mitigate CMV-related complications in vulnerable populations.
Isolation and Characterization of a Lytic Phage PaTJ Against Pseudomonas aeruginosa
Authors: Gu Jiayu , Zhang Xinqiao , Liu Tianlang , Guo Yunxue
Published: November 2024

Pseudomonas aeruginosa is a major global threat to human health, and phage therapy has emerged as a promising strategy for treating infections caused by multidrug-resistant pathogens. In this study, we isolated and characterized a Pseudomonas lytic phage, PaTJ, from wastewater. PaTJ belongs to the phage family Mesyanzhinovviridae, and is featured by short latency (30 min) and large burst size (103 PFU per infected cell). Our investigation revealed that PaTJ utilizes the type IV Pili (T4P) as a receptor. Transcriptome analysis of PaTJ infected host at latent stage showed distinct expression patterns of PaTJ encoding genes involved in replication and structure assembly, without expression of the majority of toxic accessory genes responsible for phage release. In addition, host bacteria exhibited specific induction of host metabolism-related genes in response to the PaTJ’s infection. Furthermore, our findings demonstrated the PaTJ’s potential in degrading biofilms. This work sheds light on the multifaceted impact of this lytic phage PaTJ on P. aeruginosa, presenting potential applications in both gene expression modulation and biofilm management.
Virtual Versus Reality: A Systematic Review of Real-World Built Environment Tasks Performed in CAVEs and a Framework for Performance and Experience Evaluation
Authors: Pogmore Alexander C. , Davies Richard J. , Cooke Neil J.
Published: November 2024

With operations in the built environment becoming increasingly data-rich (via Building Information Models and Internet of Things devices) and the rapid development of highly immersive environments, there are new opportunities for components of traditional “real-world” tasks to be undertaken in a “virtual” environment. However, an approach to compare both subjective (psychological) and objective (task-based) performance in real and virtual environments is rarely used in this context. This paper begins by introducing the industrial, technological, and psychological context of real-world and virtual tasks. A systematic review of the application of CAVE Automatic Virtual Environments (CAVEs) for “virtual” built environment tasks is conducted, and research gaps regarding the development of systems and comparison of task environments (CAVE and real-world condition) is identified. A theoretical framework to assess task performance is developed, and a novel practical experiment to compare participant(s) psychological and decision-making performance for an identical task in the real world and in a CAVE is proposed.
Trace Elements in Lakes Located in an Agricultural-Forest Catchment: A Case Study of Lake Raczyńskie, Poland
Authors: Wiatrowska Katarzyna , Kanclerz Jolanta , Janicka Ewelina
Published: November 2024

The enrichment of bottom sediments with trace elements due to anthropogenic factors is of growing concern worldwide. With the development of industry, agriculture, and urbanization, the risk of freshwater contamination with trace elements is increasing. As trace elements are poorly soluble in water, they have a tendency to accumulate in bottom sediments. The study focused on the evaluation of the trace element contents in the surface layer of bottom sediments of Lake Raczyńskie, located in Poland, and assessing the risks posed by these sediments. The pollution of bottom sediments was estimated based on the index of the geo-accumulation (Igeo), enrichment factor (EF), Nemerow multi-factor index (Pn), and pollution load index (PLI). The assessment of environmental risk was evaluated by the potential ecological risk index (RI) and mean PEL quotient method. The results obtained showed that the average contents of Cd, Cu, Ni, Pb, and Zn exceeded the national geochemical background values (Bn), indicating possible enrichment of bottom sediments due to human activity. Only for Mn were the observed contents below the Bn. This evaluation was confirmed by the PLI and Pn values, which indicated sediment pollution from anthropogenic sources. However, the risk assessment by RI and mean PEL showed a low risk of contamination. The results of principal component analysis (PCA) and values of Igeo and EF suggested that Cd, Cu, Mn, and Zn mainly originate from geogenic sources, while Ni and Pb probably come from an unrecognized anthropogenic source. The distribution of Cd, Mn, and Ni depended on the contents of silt and clay fractions. Additionally, organic carbon influenced Cu, Mn, Ni, and Zn contents in bottom sediments.
Investigation of Stress Tensor Anisotropy in Two- and Three-Dimensional Dunes
Authors: Fazel Najafabadi Elham , Afzalimehr Hossein , Nazari-Sharabian Mohammad , Karakouzian Moses
Published: November 2024

Investigating the creation of bed forms due to sediment transport and flow structure in the presence of bed forms in alluvial channels is a constant challenge for engineers and researchers, because of its complex nature. In this research, turbulent flow structure and turbulence anisotropy in the presence of two- and three-dimensional laboratory dunes were investigated. The results showed that, at the reattachment point, the turbulence anisotropy at the centerline of a three-dimensional dune was the largest. On the stoss slope, the turbulence anisotropy for two-dimensional dunes was at its highest at the bed form’s trough and below the crest. The results also demonstrated a tendency at the crest line toward the plane–strain limit for two-dimensional dunes and the centerline of three-dimensional dunes. However, at a 20 cm distance, turbulence anisotropy at the crest line tended toward asymmetric contraction to an oblate spheroid.
The Impact of Wafters on the Thermal Properties and Performance of In-Wheel Motor
Authors: Albana Muhammad Hasan , Putra Ary Bachtiar Khrisna , Guntur Harus Laksana
Published: November 2024

Electric vehicle (EV) proliferation is accelerating, characterized by the rising quantity of electric automobiles on global roadways. The electric machine is a crucial component of an EV, and the heat generated within the motor requires consideration as it impacts performance and longevity. A prevalent form of machine in EV is the in-wheel motor (IWM), which is notable for its compact size. However, it presents more significant cooling challenges. This research offers a new cooling method to cool the IWM. The system consists of wafters mounted on the housing of the IWM. Testing was conducted to determine the effect of wafters on the thermal properties and performance of IWMs. The machine used in this research is a brushless direct current (BLDC) motor featuring an outer rotor configuration and a peak power output of 1.5 kW. Testing was carried out experimentally and by simulation, and the simulation used Ansys Motor-CAD software. The research results show that applying wafers to IWM reduces the temperature of IWM components by up to 13.1%. IWM with wafters results in a torque increase of 0.14%, a power increase of 0.64%, and an efficiency improvement of 0.6% compared to IWM without wafters.
The COVID-19 Pandemic and Intimate Partner Violence (IPV) Among Immigrant Women in Canada: A Narrative Review
Authors: Fseifes Manal , Etowa Josephine
Published: November 2024

Introduction: The COVID-19 pandemic brought myriad challenges and disruptions to societies worldwide. The impact of the pandemic on immigrant women living in Canada and who experience intimate partner violence (IPV) was very concerning during lockdowns specifically. As Canada implemented social distancing measures and stay-at-home orders to curb the spread of the virus, immigrant women—already at a heightened risk of IPV due to factors such as language barriers and immigration status—faced an increased likelihood of being trapped in abusive situations, with limited access to essential support services such as shelters, counseling centers, and legal aid. This narrative review aims to illuminate the experiences of IPV including the challenges and strategies used to cope during the pandemic among immigrant women. While this narrative review aims to obtain an extensive understanding of the IPV experiences among immigrant women during the pandemic, it also highlights the need for developing culturally sensitive interventions to address IPV challenges for immigrant women in similar contexts. A search was undertaken of multiple databases: Medline, CINHAL, Google Scholar, and PsycINFO. To identify studies related to IPV and COVID-19, various search terms were used including “abused women”, “COVID-19”, and “IPV” and their synonyms. This review employs the social–ecological model and intersectionality to illuminate the IPV experiences of immigrant women during the COVID-19 pandemic. Four themes emerged from this study including the realities of COVID-19 restrictions; IPV vulnerabilities during the COVID-19 pandemic; the impacts of IPV and the COVID-19 pandemic; and the strategies for addressing IPV (women and system perspectives). We draw on past research and the knowledge of our multidisciplinary team of researchers to recommend culturally sensitive resources and health services for abused women living in Canada as well as highlight effective intervention strategies to address the varied and complex needs of these women.
Mentoring methodology for young specialists based on the neonatal department in the BHI VR «Medical unit SEVERSTAL»
Authors:   BHI VR “Medical Sanitary Unit “Severstal”, Cherepovets, Russia, Belyakova N. N. , Kruglova L. N. ,   BHI VR “Medical Sanitary Unit “Severstal”, Cherepovets, Russia
Published: November 2024

Neonatology is one of the most complex and responsible areas of medicine, requiring high qualifications and utmost care from medical personnel, because any mistake can have serious consequences for a newborn patient. Mentoring of young specialists in the neonatal department plays a key role in their professional development and successful adaptation to specific working conditions, helps to reduce the risk of errors in working with patients.
Interactive resource
Authors:   State Budgetary Healthcare Institution «Samara Regional Clinical Hospital named after V. D. Seredavin», Samara, Russia, Murtazina D. M.
Published: November 2024

Modern approach to employee training using digital resources. Timely delivery of information to staff. Maximum audience coverage in a short time at the Samara Regional Clinical Hospital named after V. D. Seredavin.
Recommendations of roszdravnadzor on drug safety. Safety of medical devices in the work of nurses of the oncology department (thoracic oncology)
Authors:   State Budgetary Healthcare Institution «Samara Regional Clinical Oncology Dispensary», Samara, Russia, Chernaya T. K. , Pyatikop V. M. ,   State Budgetary Healthcare Institution «Samara Regional Clinical Oncology Dispensary», Samara, Russia
Published: November 2024

The article describes the importance of compliance with drug safety requirements and the safe handling of medical devices in the departments of the oncology dispensary: accounting, issuance and control over expiration dates, compliance with the requirements and conditions for storing drugs and medical devices in accordance with orders and SOPs. Target. Improving the quality of medical care for patients in the Samara Regional Clinical Oncology Dispensary (SRCOD). Results. An effective quality control system for medical care has been organized based on the recommendations of Roszdravnadzor. Conclusion. Nursing staff complies with all requirements for drug safety and the safe handling of medical devices. Oncology dispensary nurses know that they have no right to change the form of drugs and their packaging, combine drugs from different packages into one, replace and correct inscriptions on the label with a drug, store drugs without labels. By complying with these requirements, nurses minimize errors in drug therapy. One of the important points of drug safety is preventing expired drugs from being distributed to patients.
Reuse of Fine Concrete Demolition Wastes as a Supplementary Cementitious Material in Concrete
Authors: Kheddache Lynda , Aboutaleb Djamila , Safi Brahim , Lecheb Samir , Chellil Ahmed , Mechakra Hamza
Published: November 2024

Materials from demolition are only recycled if they are economically competitive on the one hand and technically acceptable on the other, meaning they can be implemented without risking disruption to the performance of the construction material. Among these materials are demolished concretes. This type of material (waste) is currently reused as recycled aggregate, commonly referred to as gravel. Indeed, the latter contains grains of anhydrous clinker, which may play a significant role in determining the properties of concrete. In the context of waste valorization, this study focuses solely on the influence of incorporating finely crushed concrete demolition waste (CDW) as an active additive or as a supplementary cementitious material in the cement matrix used to make concrete. The results showed that the addition of up to 10% of concrete demolition waste significantly improved physical properties such as the air void content and workability of fresh concrete. Furthermore, the compactness of hardened concrete also improved based on adding 10% of CDW as a result of increasing the speed of sound. Therefore, the compressive strength of concrete was also improved by 20% when 10% waste was added compared to the control concrete. This indicates that concrete demolition waste (finely crushed) can replace cement and therefore contribute to reducing binder consumption.
Educación tributaria y contingencias fiscales del impuesto general a las ventas en empresas textiles
Authors: Curasi Cutipa Florian Roberto
Published: November 2024

La educación tributaria es un factor esencial para que los contribuyentes cumplan de manera correcta y oportuna sus obligaciones tributarias. El objetivo de la investigación fue determinar la relación que existe entre la educación tributaria y las contingencias fiscales del Impuesto General a las Ventas en las empresas textiles de San Martín de Porres, 2024. La metodología empleada fue de enfoque cuantitativo, nivel descriptivo-correlacional, diseño no experimental, técnica encuesta, instrumento cuestionario, con una población y muestra de 498 y 218 administradores/gerentes y contadores de dichas organizaciones, respectivamente. De los resultados alcanzados en la investigación se tienen que hay una relación significativa baja entre la educación tributaria y contingencias fiscales del Impuesto General a las Ventas en empresas textiles, debido a que el nivel de significación logrado fue de 0.001, mientras el coeficiente de correlación fue de 0.294. Concluyéndose que la mayoría de tales colaboradores no se actualizan dichos conceptos para determinar sus deberes fiscales, por lo que dichas compañías tienen reparos y multas tributarias.
Diversidad en el aula: impacto de la educación inclusiva en estudiantes con necesidades educativas especiales
Authors: Ruiz Piza Angélica Lucia
Published: November 2024

La diversidad en el aula es un fenómeno que refleja la rica variedad de capacidades, estilos de aprendizaje y experiencias de los estudiantes. El objetivo del estudio es explorar la diversidad en el aula y su impacto de la educación inclusiva en estudiantes con necesidades educativas especiales. Con enfoque cualitativo, paradigma sociocrítico con metodología de investigación acción. Se realiza una revisión bibliográfica del tema y la población es una muestra de 25 niños. Los hallazgos revelan que, el desafío actual, en materia de inclusión educativa desde el aula, es formar escuelas que eduquen en la diversidad, el respeto y valoración de estas, y en donde todos los alumnos tengan acceso a una educación de calidad que les permita su pleno desarrollo, aprendizaje y participación. Como conclusión se constatan limitaciones relacionadas con la carencia de procedimientos educativos adecuados a las potencialidades de los niños con necesidades educativas especiales de edades entre 3 y 5 años.
The Birds and The Bees: Teaching Parents How to Educate their Children about Sex
Authors: Pell Tonya , Aldrich Courtney
Published: November 2024

Parent educators at Michigan State University Extension have had great success with their Extension Extras Parenting Hour series which began in 2020. The series is organized every quarter, meets weekly, and changes topics every week. The 90 minute class covers a range of parenting topics from positive discipline, talking to children about race, early literacy, and now, due to a need being identified and addressed, how to educate children about sex and sexuality. This new topic to the series has received positive feedback from participants and has led to community organizations asking for similar classes and support from the team.
Research verification is effective for Extension programs in aquaculture
Authors: Roy Luke , Kelly Anita , Hanson Terry , Dorman Larry , Recsetar Matthew , Quintero Herbert
Published: November 2024

Extension professionals have used research verification programs to evaluate the effectiveness of research-based management recommendations in several different aquaculture species. In addition to providing a platform on which to examine current best management practices and Extension recommendations from Land Grant Universities, research verification is valuable in identifying gaps for further research. Perhaps the best benefit of research verification programs are the comradery and relationships developed between cooperating commercial producers and Extension personnel that can lay the groundwork to facilitate future collaborative efforts related to technology transfer in the aquaculture industry.
Impacting Community Well-Being Through Effective Engagement Using the SEED Method
Authors: Rafie Carlin , Zimmerman Emily , Hargrove Angelina , Amissah Theodora , Lee Samantha
Published: November 2024

Cooperative Extension can make a significant impact on health in the United States through effective community engagement that focuses on the complex socio-ecological factors that impact health. The Stakeholder Engagement in Question Development Method (SEED Method) employs community based participatory research principles to engage communities in research, problem-solving, and action planning. Projects employing the SEED Method engage community members from diverse backgrounds, create community capacity, result in tangible outcomes, and foment inter-organizational trust and networking. A SEED Toolkit is available on the Extension Foundation Campus site and provides implementation instructions, tools and timelines, and potential applications within Extension.
Building Extension Professional’s Capacity to Engage Volunteers: Evaluation of the Developmental Stages of an Extension Professional Model
Authors: O'Neil Kandi , Vettern Rachelle , Harrington Rebecca , Maass Sarah , McGlaughlin Patricia , Gauley Josset
Published: November 2024

The Developmental Stages of an Extension Professional (DSEP) model depicts how professionals can move through the stages of service, education, management, and leadership to build volunteer and program capacity. It encourages Extension professionals to assess the situation and adjust their leadership style.

Researchers used a mixed methods approach to assess Dr. James Rutledge’s DSEP model. Findings confirmed training Extension professionals in the DSEP model throughout the Achieving the Extension Mission through Volunteers course led to positive behavior change when working with volunteers. Extension needs to train professionals and utilize the DSEP model to build program capacity through volunteer engagement.
Extension Education for Real Estate Professionals: Teaching Regulations and Sharing Resources That Protect Water Quality and Property Values
Authors: Patterson Linda , Halik Shari , Stepenuck Kristine
Published: November 2024

Real estate professionals can be an important source of information for home buyers and sellers about regulations and practices that protect water quality and properties from environmental damage. Lake Champlain Sea Grant (LCSG) Extension identified a deficit in real estate education covering these topics for real estate professionals. Accredited real estate workshops were initially developed by LCSG Extension and Vermont Agency of Natural Resources specialists. The program was later expanded to New York. Six-month follow-up surveys indicated that the majority of participants continued to use knowledge and tools gained in the workshops. Suggestions for replicating this program elsewhere are provided.
الانتقال من التمويل المركزي إلى تفعيل دور التمويل المحلي: قراءة في تجربة الإصلاح المالي في الصين خلال 1957-2020
Authors: Benatallah Aicha
Published: November 2024

تركز هذه الدراسة على مناقشة مراحل الإصلاح المالي في الصين التي بدأت منذ سنة 1957، وتأثير عملية الإصلاح المالي على العلاقة المالية بين الحكومة المركزية والحكومات المحلية الصينية، وعلى نمو بنود الميزانية العامة في الصين خلال فترات الإصلاح الى غاية عام 2020. ولقد خلصنا إلى وجود نمو كبير ومستمر للنفقات العامة والإيرادات العامة، يعود سببها إلى عوامل اقتصادية وأخرى مالية نتيجة الإصلاح المطبق، كما وجدنا أن حصة الحكومات المحلية من إجمالي النفقات العامة اكبر من حصة الحكومة المركزية، أما بالنسبة لمساهمة الحكومات المحلية من الإيرادات العامة فقد عرفت محصلة الإيرادات المحلية نمو متذبب، في ظل تزايد الاهتمام بتوفير موارد مالية محلية ضمن خطط الإصلاح المطبقة التي تعمل على تلبية الحاجيات وتوفير الخدمات العامة بما يخدم الأقاليم والاقتصاد الصيني بشكل عام.
النوافذ الإسلامية في البنوك التقليدية العمومية - دراسة مقارنة بين التشريع العراقي والتشريع الجزائري -
Authors: Bougassa Mouad
Published: November 2024

هدفت هذه الدراسة إلى تحليل الوضعية القانونية للصيرفة الإسلامية، وخاصة النوافذ الإسلامية، في كل من العراق والجزائر، والمقارنة بينهما من أجل تحديد أهم النقاط التي يمكن للمشرع الجزائري أن يستفيد فيها من نظيره العراقي لتطوير الصيرفة الإسلامية. وتأتي هذه الدراسة في خضم توجه الحكومة الجزائرية للصيرفة الإسلامية ودعمها بغرض امتصاص الكتلة النقدية المتداولة خارج السوق الرسمية. وقد خلصت الدراسة إلى وجود تشابه كبير بين التشريعين العراقي والجزائري حول الصيرفة الإسلامية بشكل عام، إلا أن المشرع العراقي تفوق على نظيره الجزائري في بعض التفاصيل التي يمكن لهذا الأخير أن يستفيد منها، ومن ذلك: الشروط التي يجب توفرها في أعضاء هيئة الرقابة الشرعية، تحديد الأنشطة المباحة والمحظورة، إلى غير ذلك.
Contracting Assistance in the Era of Digital Transformation in Algeria.
Authors: Ramdani Kamel , Guetib Abdelkader
Published: November 2024

This research aims to present the concept of contracting assistance and its essential services. It also explores the concept of digital transformation and outlines its key requirements. The research seeks to assess the reality of contracting assistance in the context of digital transformation in Algeria, relying on indicators of the Arab digital economy. It investigates the mechanisms used to implement contracting assistance by initiating digitization as a preliminary step. Finally, the paper sheds light on some features of digital transformation in the application of contracting assistance through digital platforms and websites. Ultimately, it concludes with a set of important suggestions to contribute to the enhancement of digital transformation, particularly in the field of entrepreneurship.
Economic determinants of per capita carbon dioxide emissions An econometric comparative study between Algeria and the United States of America during the period (1990-2022).
Authors: Haid Merwan
Published: November 2024

There is no doubt that estimating the equation of carbon dioxide emissions per capita in Algeria and comparing it with one of the largest countries causing these emissions helps a lot in avoiding the negative environmental waste resulting from it. Therefore, comparative standard studies continuously occupy a special space, and impose themselves as an important scientific branch, given the considerable role played by the power values of this dangerous gaseous substance, like other environmental, economic and social phenomena, in drawing and directing ideal programs and policies.
        Through this study, we will try to narrate the reality of carbon dioxide emissions and compare the individual’s share of carbon dioxide emissions between Algeria and the United States by taking the past of this phenomenon as a basis for estimating its equation in terms of some economic variables according to the literature of the study using the Autoregressive Distributed Lag (ARDL) model.
الثقافة المقاولاتية لدى طلبة الجامعات الجزائرية
Authors: HAROUN Samira , ARABI Mahfoud
Published: November 2024

هدفت هذه الدراسة إلى تقصي واقع ومستوى الثقافة المقاولاتية لدى الطالب الجامعي في الجزائر، باعتباره الثروة الحقيقية للتحول الاقتصادي والاجتماعي، وقد اعتمدنا في دراستنا على المنهج الوصفي التحليلي وذلك لملائمته لأهداف الدراسة، كما تم استخدام البرنامج الإحصائي "SPSS" لتحليل البيانات والمعلومات التي تم جمعها عن طريق الاستبيان من عينة متكونة من 400 طالب جامعي، في مختلف المستويات والتخصصات، وقد توصلت الدراسة إلى أن درجة تقدير طلبة الجامعات الجزائرية لمستوى الثقافة المقاولاتية لديهم جاءت بمتوسط 3,72 وبانحراف معياري قدر ب 0,861 وهو مستوى مرتفع مع عدم وجود فروق ذات دلالة إحصائية عند مستوى المعنوية (α = 0,05) بين متوسطات درجات تقدير أفراد عينة الدراسة لمستوى الثقافة المقاولاتية لديهم تعزى لمتغيري الجنس، العمر، الجامعة والتخصص، وأوصت الدراسة بضرورة تعميم تدريس المقاولاتية لجميع التخصصات الجامعية لتعزيز الثقافة المقاولاتية مع الاهتمام بالطلبة أصحاب الأفكار والمشاريع من خلال الدعم والمرافقة قبل وأثناء الانطلاق في تجسيد مشاريعهم.
The Negative Impact of Deepfake Technology on the Reputation of Prominent Figures on Social Media Platforms: An Analytical Study on a Sample of Fabricated Videos
Authors: kadem Djamila , mohamed eltaib Lassouane Kafia
Published: November 2024

This research paper explores the detrimental impact of deepfake technology on the reputation of prominent figures on social media platforms. The rapid advancement of deepfake technology and its negative consequences on digital life necessitate a thorough investigation of this issue. The research aims to understand the influence of deepfake technology on public perception of prominent figures and develop strategies to mitigate its harmful effects.
The methodology involves analyzing manipulated videos to identify indicators of deepfake manipulation. The findings demonstrate the significant impact of deepfake videos on individuals' reputations, both personally and professionally. The research emphasizes the urgent need to enhance digital literacy among users and implement mechanisms to combat deepfake technology.
 It underscores the importance of adopting robust digital security policies and intensifying scrutiny of suspicious content on social media platforms. The study concludes by highlighting the escalating digital challenges and the necessity for proactive measures to protect the reputations of individuals targeted by deepfake technology.
Aspectos nutricionais de portadores de doença hepática gordurosa não alcoólica
Authors: Nunes Alessandra Vitória de Menezes , Farias Rebeca Gonçalves , Melo Neto Eduardo Vieira de , Santana Breno Wagner Paes , Cruz Josilda Ferreira
Published: November 2024

Introdução: A doença hepática gordurosa não alcoólica corresponde a um espectro de lesões hepáticas que vão desde o simples acúmulo de triglicerídeos nos hepatócitos, a esteatose hepática, até a esteatohepatite não-alcoólica, que, além da esteatose, se apresenta como injúria inflamatória, fibrose e balonização dos hepatócitos, podendo eventualmente levar a cirrose e carcinoma hepatocelular. Todas essas alterações têm em comum a associação com aspectos nutricionais, os quais podem ser avaliados a partir de medidas antropométricas. Objetivo: Relacionar a esteatose hepática não alcoólica diagnosticada pela ultrassonografia abdominal com aspectos nutricionais dos pacientes. Método: Estudo clínico, transversal, descritivo, tipo survey, com abordagem analítica quantitativa. Os dados foram colhidos entre o período de janeiro de 2024 a julho de 2024 em uma clínica ultrassonográfica na cidade de Aracaju-SE. A coleta dos dados foi realizada em 2 fases e os resultados foram analisados sob forma descritiva e inferencial. O trabalho foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: Foram avaliados 273 pacientes com idade entre 18 e 70 anos. Desses, 53,1% dos pacientes não possuíam  infiltração gordurosa hepática, 21% apresentavam grau 1, 21,8% grau 2 e 4,2% grau 3. Conclusão: Houve relação estatisticamente significativa entre dados antropométricos e a presença e gravidade da doença hepática gordurosa não alcoólica.
A dosagem da carga viral e o uso de terapia antirretroviral como fatores influenciadores na transmissão vertical do HIV no Brasil
Authors: Silva Júlia Oliveira , Lima Maria Fernanda Araujo Barbosa , Oliveira Phaedra Castro
Published: November 2024

A transmissão vertical (TV) do Vírus da Imunodeficiência Humana (HIV) é a passagem do patógeno da mãe soropositiva para o filho relacionada aos níveis elevados de carga viral materna, às infecções sexualmente transmissíveis não tratadas, à falta de acesso à terapia antirretroviral (TARV) e à amamentação. O objetivo do estudo é quantificar a TV no Brasil com análise da dosaem de carga viral no parto e da adesão à terapia antirretroviral em cada região do país. Foi realizada a coleta de dados, entre Outubro de 2022 e Julho de 2023, pelo Sistema de Informação de Agravos de Notificação (SINAN) e pelo painel de indicadores epidemiológicos do Departamento de Condições Crônicas e Infecções Sexualmente Transmissíveis. A TV é a principal forma de transmissão do vírus nas crianças e apresentou redução de 92,42% entre 2013 e 2021, o Nordeste teve a maior prevalência enquanto o Sudeste e o Sul obtiveram menos casos. Ademais, o tratamento precoce é evidente visto que houve aumento na TARV experimentada em 17,89%, redução da TARV não iniciada e não experimentada em em 2,21% e 15,68%, respectivamente. A quantidade de carga viral periparto aumentou nos valores menores de 50 cópias/ml e reduziu nos valores maiores com evidente diminuição do risco de TV. Assim, a TV do HIV pode ser reduzida com intervenções preventivas e terapêuticas como a utilização precoce e adequada da TARV por gestantes soropositivas e a consequente diminuição da carga viral materna e a probabilidade de transmissão para o bebê.
Qualidade de vida pós-infarto agudo do miocárdio
Authors: Branco Beatriz Moraes dos Santos , Vieira Luciana Aparecida , Gentile Isabelle , Garcia Maria Eduarda Franques Barros
Published: November 2024

Introdução: O Infarto Agudo do Miocárdio (IAM) ocorre devido à obstrução arterial por um coágulo, impedindo a oxigenação adequada do tecido cardíaco. Qualidade de Vida (QV) envolve subjetividade, multidimensionalidade e bipolaridade, relacionando o indivíduo com aspectos positivos e negativos de sua vida. Objetivo: Este estudo busca compreender como o IAM afeta a QV dos pacientes. Método: A pesquisa foi conduzida em bases como Pubmed e Scielo, selecionando 400 artigos, dos quais 14 foram incluídos na revisão. Resultados: Os resultados mostram que muitos pacientes evitam retornar à rotina por medo de um novo IAM, mas atividades supervisionadas ajudam a melhorar a autoconfiança e promovem a recuperação gradativa. A reabilitação com exercícios supervisionados também contribuiu positivamente para a QV. Conclusão: A conclusão ressalta que a QV está ligada às limitações impostas pela doença, afetando a interação social e o progresso no tratamento.
Aplicação de Laser terapia em cirurgias orais complexas
Authors: Cordeiro Jony José Fernandes , Silva Camila Oliveira da , Lira Ricardo Martins
Published: November 2024

A exodontia de terceiros molares é considerada uma cirurgia invasiva e de alta complexidade, por esse motivo se torna um procedimento suscetível a complicações e acidentes, tendo a Laserterapia como forma de ajudar no tratamento dessas intercorrências. Objetivo: abordar o uso de Laserterapia em procedimentos odontológicos que sejam complexos e envolvam processos de cicatrização mais longos, tendo o uso dos lasers de alta e baixa potência como diferencial no tratamento. Metodologia: a pesquisa consistiu em uma revisão qualitativa de artigos publicados de 2018 a 2022. Realizou-se pesquisas nos bancos de dados do Scielo e Google Acadêmico, utilizando-se como descritores as palavras chaves “laserterapia”, “laser de baixa intensidade”, “laser de alta intensidade” e “cirurgias odontológicas”. Resultados: foram selecionados 25 artigos, excluídos 7 por não estarem de acordo com o estudo, removidos 6 por fugirem totalmente do assunto, incluídos 12 artigos por seguirem os critérios de inclusão da pesquisa. Conclusão: cirurgias orais complexas possuem a necessidade de amenizar a sintomatologia de diversas intercorrências, devido a esse fato, o uso de laserterapia foi indicado. O estudo mediante a essa terapia reitera os seus benefícios e a relevância da sua aplicação para tais procedimentos.
El compromiso como factor influyente para la motivación del cumplimiento tributario de contribuyentes profesionales
Authors: Molina Diana Verónica Terán , Toalombo Wilmer Olmedo Espinoza , Mourad Antoine Sébastien
Published: November 2024

Aunque la mayoría de los países latinoamericanos han experimentado un fuerte incremento de sus recursos tributarios como proporción del PIB, todavía existe resistencia por parte de los pequeños contribuyentes a la hora de pagar impuestos. El objetivo de este estudio fue determinar la influencia del compromiso en la motivación de cumplimiento tributario de los contribuyentes profesionales debido a los constantes cambios en las leyes tributarias ecuatorianas que afectan el cumplimiento tributario. La investigación se realizó con un enfoque cuantitativo, diseño no experimental y alcance descriptivo, basado en teorías que permitieron identificar el nivel de compromiso como variable independiente y la motivación como variable dependiente, utilizando una muestra aleatoria de profesionales que cuentan con identificación tributaria y que residen en la ciudad de Guayaquil - Ecuador. El 96% de los encuestados cumple con sus obligaciones tributarias con el propósito de evitar contratiempos con los organismos de control y motivados por cumplir con la norma social entre los contribuyentes; una de las mayores motivaciones es hacer lo correcto, cuyo propósito es ayudar al crecimiento del país. Por otro lado, se determinó que el compromiso no es el único factor determinante en la motivación del cumplimiento tributario, existiendo otros factores como los económicos o demográficos que podrían influir en los profesionales.
Challenge of defining a global concept for handicrafts sector: an economic perspective
Authors: Benlamoudi Djalila , Derbal Soumeia , Zakia Mahlous , Mohamed Trifa
Published: November 2024

Addressing the topic of handicrafts requires defining its concept, as the process of definition helps identify the beneficiaries of this sector, thereby facilitating the preparation of support programs for these beneficiaries. This also allows for understanding one of the lines of development in countries, through which nations can determine the model or form of economic development they will adopt. Based on this premise, this article aims to discuss the most important concepts used to describe handicraft at the international level,along with an attempt to establish a comprehensive definition that outlines the features of the sector.
Pengaruh edukasi kesehatan menggunakan board game terhadap pengetahuan dan sikap pemilahan sampah
Authors: Maulidina Adhim Fahmarani , Wandi Wandi , Rachman Moh Zainol
Published: November 2024

Latar Belakang: Pemahaman masyarakat tentang pengelolaan sampah dan risiko lingkungan yang ditimbulkan oleh sampah masih sangat minim, terutama di kalangan anak usia sekolah. Penelitian ini bertujuan untuk mengetahui pengaruh edukasi kesehatan menggunakan board game terhadap tingkat pengetahuan dan sikap tentang pemilahan sampah siswa sekolah dasar.Metode: Penelitian ini merupakan penelitian kuantitatif berbentuk one group pre-post. Sampel diambil menggunaan teknik total sampling sejumlah 49 responden.Hasil: Sebelum menerapkan kurikulum permainan papan Penelitian menunjukkan bahwa lebih dari 50% dari mereka yang mengikuti survei kurang memiliki pemahaman yang cukup. Melanjutkan permainan papan setelah sekolah Hasil penelitian menunjukkan bahwa hampir semua responden memiliki pemahaman yang kuat. Terlihat bahwa sebagian besar peserta memiliki pandangan pesimis sebelum menerapkan instruksi permainan papan. Melanjutkan permainan papan setelah sekolah Menurut temuan, sebagian besar orang yang mengikuti survei memiliki pandangan optimis.Kesimpulan: Permainan board game ular tangga dapat menjadi alternatif media belajar yang tepat untuk meningkatkan pengetahuan dan sikap tentang pemilahan sampah siswa sekolah dasar
Pengaruh pemberdayaan kader Jumantik terhadap perilaku pencegahan demam berdarah dengue di Karangbesuki Malang
Authors: Puspitasari Dyah Ayu , Hadi Sugianto , Lala Handy
Published: November 2024

Latar Belakang: Demam berdarah dengue menjadi masalah kesehatan utama di Indonesia saat 2023, dengan jumlah kasus ada 57.884 kasus dan 422 kematian yang dilaporkan oleh Kementerian Kesehatan (Kemenkes). Penelitian ini bertujuan untuk mengkaji bagaimana pemberdayaan kader jumantik di Kelurahan Karang Besuki, wilayah Puskesmas Mulyorejo mempengaruhi upaya masyarakat untuk terhindar dari penyakit demam berdarah dengue (DBD).Metode: Penelitian kuantitatif ini yang menggunakan one-group pre-post design dan pendekatan total sampling. Lembar observasi berupa kuesioner pengetahuan dan sikap. Responden penelitian berjumlah 50 orang.Hasil: Hasil penelitian menandakan yaitu pengetahuan (p=0,003), sikap (p=0,004), dan perilaku (p=0,000) saling dipengaruhi, dengan nilai p sejumlah 0,000 ≤ 0,05.Kesimpulan: Hasil penelitian menandakan yaitu pemberdayaan kader jumantik memengaruhi perilaku di Kelurahan Karang Besuki, wilayah operasional penelitian, dalam hal pencegahan demam berdarah dengue.
Hubungan tingkat pengetahuan dengan kepatuhan dalam mengkonsumsi obat antihipertensi
Authors: Arini Arini , Wijaksono Muhammad Arief , Tasalim Rian
Published: November 2024

Latar Belakang: Hipertensi termasuk penyakit silent killer yang penyebab utama kematian di seluruh dunia. Masih tingginya angka kejadian penderita hipertensi dikarenakan ketidakpatuhan dalam pengobatan. Keberhasilan pengobatan antihipertensi sangat bergantung pada pengetahuan dan kepatuhan pasien.Metode: Penelitian kuantitatif dengan rancangan analitik korelasi dan pendekatan cross sectional ini dilakukan pada 30 penderita hipertensi yang dipilih dengan teknik purposive sampling. Data diambil menggunakan kuesioner pengetahuan dan kuesioner kepatuhan MMAS-8. Data penelitian ini dianalisa dengan uji rank spearman.Hasil: Sebagian besar responden masuk kategori dewasa dengan pendidikan terakhir SD berjumlah 17 responden. Hampir seluruh responden berjenis kelamin perempuan, dimana sebagian besar menderita hipertensi derajat 2 kurang dari 10 tahun. Hasil uji rank spearman menunjukkan nilai p = 0,009 dan coefficient correlation = 0,472.Kesimpulan: Hasil Analisa menunjukkan terdapat hubungan yang cukup kuat antara tingkat pengetahuan dengan kepatuhan dalam mengkonsumsi obat antihipertensi di Puskesmas Pekauman Banjarmasin.
Pengaruh kohesi sosial terhadap resiliensi masyarakat dalam menghadapi bencana tsunami
Authors: Permana Iwan , Budhiana Johan , Dewi Rosliana , Fera Melinda
Published: November 2024

Latar Belakang: Bencana menghadirkan perubahan dan memaksa individu keluar dari rutinitas normalnya sehingga penting membangun resiliensi. Namun, pembentukan resiliensi membutuhkan kohesi sosial dalam masyarakat. Tujuan penelitian ini untuk mengetahui pengaruh kohesi sosial terhadap resiliensi masyarakat dalam menghadapi bencana tsunami.Metode: Jenis penelitian korelasional pendekatan cross sectional. Sampel sebanyak 300 responden dengan menggunakan purposive sampling. Uji validitas dinyatakan valid (p-value <0,05). Uji reliabilitas variabel Psychological Sense of Community sebesar 0,542, Neighboring sebesar 0,348, Attraction sebesar 0,519, dan resiliensi sebesar 0,902. Pengambilan data menggunakan kuisioner dan analisis statistik menggunakan regresi linier sederhana dan regresi linier berganda.Hasil: Variabel psychological sense of community memiliki nilai mean 22,21, neighboring memiliki nilai mean sebesar 15,67, attraction memiliki nilai mean sebesar 18,96, serta resiliensi masyarakat memiliki nilai mean sebesar 44,19. Terdapat pengaruh signifikan psychological sense of community (p=0,000), neighboring (p=0,000),  dan attraction (p=0,000) terhadap resiliensi masyarakat.Kesimpulan: Terdapat pengaruh kohesi sosial terhadap resiliensi masyarakat.
Hubungan gaya hidup dengan kejadian diabetes mellitus Tipe 2 di Rumah Sakit Royal Prima Medan
Authors: Elisabeth Elisabeth , Suhartina Suhartina , Wienaldi Wienaldi
Published: November 2024

Latar Belakang: Salah satu jenis diabetes yang paling umum, diabetes melitus tipe 2 yang memengaruhi 90% populasi dunia sebagai akibat dari pilihan gaya hidup yang tidak sehat. Kebaruan penelitian tentang gaja hidup pasien penderita diabetes melitus type 2 di rumah sakit royal prima medan. Penelitian bertujuan mengetahui hubungan gaya hidup dengan kejadian DM tipe 2 pasien di RS Royal Prima Medan dan pemahaman responden tentang gaya hidup sebagai pemicu.Metode: Penelitian kuantitatif cross-sectional digunakan untuk meneliti suatu fenomena. Penelitian melibatkan pasien Rumah Sakit Royal Prima Medan dari April sampai Juni 2024. Data dari 50 pasien rawat jalan dan dianalisis menggunakan SPSS pada analisis bivariat dan univariat.Hasil: Penelitian menemukan bahwa terdapat hubungan yang signifikan antara gaya hidup dengan kejadian Diabetes Mellitus diantaranya pola makan (p = 0,02), aktivitas fisik (p = 0,02), kebiasaan merokok (p = 0,04), manajemen stres (p = 0,01), pola tidur (p = 0,04). Variabel yang tidak memiliki hubungan signifikan antara gaya hidup dengan kejadian Diabetes Mellitus adalah konsumsi alkohol (0,27).Kesimpulan: Konsumsi alkohol merupakan faktor gaya hidup paling krusial dalam meningkatkan risiko timbulnya gejala diabetes melitus. Hasil tidak signifikan kebiasaan merokok dan pola tidur tidak dapat diabaikan sebagai faktor pengaruh peningkatan resiko timbulnya gejala diabetes melitus.