bluuebunny/crossref_metadata_2025 huggingface dataset:
The role and place of the constitutional acts of the Ukrainian Central Rada in the history of Ukrainian state formation
Authors: Ozel V.I.
Published: March 2024

The article is devoted to the analysis of the state- building activities of the Ukrainian Central Rada, which was embodied in constitutional documents.The key place of the Ukrainian People’s Republic (1917-1918) in the general historical process of Ukrainian state formation is substantiated.The content of the acts of the Ukrainian People’s Republic, which in its short time of existence went from the birth of the national state apparatus to the development and adoption of its own Constitution, was considered and analyzed.The central place among the acts of the UCR is occupied by the four Universals proclaimed by it.Using the methods of systematic and comparative analysis of the texts of these documents, it was possible to: 1) trace the evolution of the national identification of the Ukrainian state: from autonomy to independence; 2) the mechanisms of the formation of the state-authority apparatus and the formation of the democratic foundations of the division of power into branches are analyzed; 3) the norm-making potential of the Ukrainian Central Committee was analyzed. A general review of the rule-making activity of the Ukrainian Central Rada regarding the establishment of norms of a constitutional nature makes it possible to understand that the political and legal idea was aimed at the formation of a democratic republican state system.The positive aspects of the state-building experience of the Ukrainian People’s Republic (1917-1918) were: defense of national interests, democratic development of state institutions, recognition and consolidation of fundamental human rights and freedoms, and their social direction. The policy miscalculations carried out by the Ukrainian Central Council include: maintaining stable ties and hoping for democratic development alongside Russia; chaotic decisions, which is connected, on the one hand, with the lack of experience, and on the other - with the pressure of the russian authorities.
Measures of a criminal legal nature, which are applied for criminal offences that encroach on pharmaceutical activity, outside the limits of criminal responsibility
Authors: Frolova O.
Published: March 2024

The article deals with the measures of a criminal legal nature, which are applied for criminal offences that encroach on pharmaceutical activity, outside the limits of criminal responsibility.

In the opinion of the author, such measures of a criminal legal nature are beyond the scope of criminal responsibility, such as: exemption from criminal responsibility; restrictive measures applied to persons who have committed domestic violence; coercive measures of a medical nature; coercive educational measures; forced treatment; special confiscation; measures of a criminal legal nature against legal entities.

Attention is focused on the fact that clarifying the specifics of the application of some of these measures is directly related to the implementation of the norms of the Criminal Code of Ukraine, which provide criminal legal protection of pharmaceutical activity in Ukraine. After all, the relevant norms of the Special Part of the Criminal Code of Ukraine provide for special types of exemption from criminal responsibility (Part 4 of Art. 307, Part 4 of Art. 309, Part 4 of Art. 311, Part 5 of Art. 321, Part 4 of Art. 321-1 of the Criminal Code of Ukraine), and the definition of the concept of special confiscation in Part 1 of Art. 96-1 of the Criminal Code of Ukraine directly includes its application for certain types of the mentioned criminal offences.

The article considers the specifics of the application of special confiscation (in particular, for such types of criminal offences that encroach on pharmaceutical activity and are provided for in Parts 2-5 of Art. 134, Art. 138, 142, 305, 306-308, Parts 2, 3 of Art. 309, Art. 312, 314-317, 320, 321, 321-1, 321-2, 322, Parts 2-4 of Art. 323, 324 f the Criminal Code of Ukraine).

The author paid special attention to the specific content of the prerequisites and grounds in the legal constructions of special types of exemption from criminal responsibility provided for in Part 4 of Art. 307, Part 4 of Art. 309, Part 4 of Art. 311, Part 5 of Art. 321, Part 4 of Art. 321-1 of the Criminal Code of Ukraine.

The author substantiates the relevance of the application of criminal-legal measures against a legal entity for the commission by an authorized entity of a legal entity on behalf and in the interests of this legal entity of criminal offenses provided for in Art. 142, 306, 307, 311, 312, 320, 321, 321-1, 321-2, 322 of the Criminal Code of Ukraine.
READINESS ANALYSIS OF OVO DIGITAL PAYMENT IMPLEMENTATION AT COFFEE STORE USING THE TECHNOLOGY ACCEPTANCE MODEL (TAM) METHOD ( Study Case: Kontekstual Coffee )
Authors: Mubarak Muhammad faiz Rizza , S.Kom., M.MT Sarah Astiti , S.T.,S.Si.,MMSI Resad Setyadi
Published: March 2024

Digital payments are a new technological development as financial technology (Fintech). The purpose of this study is to analyze readiness and find out influencing factors _ the level of use of OVO as a digital payment tool in the context of coffee with use TAM variable perceived usefulness (PU) , perceived ease of use (PEU), Atittude Toward Using (ATU), Behavioral Intention (BI). The analysis model of this research uses the Technology Acceptance Model (TAM). Retrieval technique sample used is technique sample convenience. While the data obtained in the form of primary data because data collection is done with method spread online questionnaire. As much 50 results questionnaire accepted and all could processed by researchers. Data analysis is carried out with use technique analysis using statistical product and service solutions (SPSS) programs. The research results obtained is PU, PEU, and ATU have positive influence to BI, as well as PU and PEU have positive influence to ATU.
Macrozoobenthic biodiversity: an indicator of water quality in Ngrowo River, Tulungagung, East Java
Authors: Punjungsari Tyas Nyonita , Azizah Luthfi Ainul
Published: March 2024

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Performance of gender diversity on board of directors: The case of Indonesia
Authors: Juniarti Juniarti , Jie Ferry
Published: March 2024

This study further explores women’s role in top management in Indonesia, where men still dominate that position. This study underlines the role of women’s boards of commissioners in producing better financial performance in the specific sectors, manufacturing and service sectors, where the power of women to lead these sectors is more optimal. The sample is selected from the Indonesia Stock Exchange for the period 2009–2018. The final sample is 780 observations. This study applies panel data, which is more robust when controlling heterogeneity. Data panel regression is applied to analyze data. This study finds that gender diversity harms market-based performance, while from accounting-based measures, gender diversity has a significant positive effect. This study is applied explicitly in the manufacturing and services industrial sectors; therefore, carefully generalizing the results is necessary. Research in other specific sectors is very open to obtaining specific results in various industries, including developing countries other than Indonesia. The market has not trusted the role of women in top management; there is still a kind of ‘hidden distrust’ about the capabilities of women in running the top leadership captain. The market needs more substantial evidence to believe in women’s performance on the board of directors. Therefore, it is necessary to provide wider opportunities for women to sit on the board of commissioners, as much as men have.
Spatial structure of natural landscapes within the Chornobyl Exclusion Zone
Authors: Fedoniuk Tetiana P. , Pyvovar Petro V. , Skydan Oleh V. , Melnychuk Taras V. , Topolnytskyi Pavlo P.
Published: March 2024

The article demonstrates the results of a study of the landscape structure of the Chornobyl Radiation and Ecological Biosphere Reserve (Ukr.: Chornobylskyi radiatsiino-ekolohichnyi biosfernyi zapovidnyk – ChREBR). Because of radioactive pollution, a sharp drop in human activity, and the granting of the territory the status of a protected object, the process of area rewilding took on certain characteristics and led to the return of ecosystems’ natural processes. The studies cover a 7-year period from 2016 to 2022, i.e., from the moment this territory was granted protected status. That territory was abandoned by people more than 37 years ago and the former rural and urban landscapes have either already been transformed or are in the process of being transformed into natural ones. The scale of forest massifs has changed during the previous seven years, which has caused increased pasture overgrowth. huge forest massifs have been lost because of enormous forest fires and floods, particularly along the Pripet and Uzh rivers. Semi-natural successions occur in the gardens, and wooden homes are almost extinct. From orbit, a number of communities no longer resemble settlements. They are cloaked in bushes and trees instead. For places that have been ploughed, the same holds true. The last seven years show that change is happening more slowly than in the decades before. The pattern of natural processes in ecosystems, including periodic fires, the blocking of reclamation channels, and other factors, is the primary driver of changes in the composition of the land cover.
The microbial and chemical risk analysis of drinking water in a small island, Spermonde Archipelago
Authors: Birawida Agus B. , Daud Anwar , Ibrahim Erniwati , Hidayanty Healthy , Sila Nurlia , Maming Maming , Nur Muhammad , Khaer Ain , Arundhana Andi I. , Arsin Arsunan
Published: March 2024

Coastal areas face greater risk in terms of health and the environment. They are the most vulnerable to impacts resulting from climate change. Coastal areas with higher population density also have more environmental problems, such as natural disasters. Environmental health risks from chemicals and microbes continue threatening people living on small islands. Therefore, this study aims to: 1) conduct a chemical risk analysis of heavy metals Pb, Cr(VI), and Ni; 2) analyse the microbial risk posed by drinking water consumed daily by people on small islands. A method used to analyse the chemical risk of heavy metals was the environment health risk assessment (EHRA), whereas to analyse the microbial risk in small islands, the quantitative microbial risk assessment (QMRA) was used. The results showed that the concentration of heavy metals in drinking water was <0.0012 mg∙dm–3 for Pb, <0.01 mg∙dm–3 for Cr(VI), and <0.0019 mg∙dm–3 for Ni. The three heavy metals showed worrying results. Assessment and obtained risk quotient were less than one (RQ < 1) in all samples. Meanwhile, the microbial analysis found Escherichia coli, Acinetobacter calcoaceticus, Enterobacter sp ., and Citrobacter sp ., with risk characterised from low to high. Risk management is needed to control environmental health risks posed by heavy metals and the microbiological characteristics of drinking water on the small islands of the Spermonde Archipelago.
Przestrzeń przed Muzeum Narodowym w Krakowie jako wynik konkursu z połowy XX wieku
Authors: Wowczak Jerzy
Published: March 2024

Wylot ulicy Wolskiej, z którego rozpościerał się widok na Błonia z górującym nad nimi kopcem Kościuszki, został w planach konkursowych Wielkiego Krakowa z 1910 roku wskazany jako ważne miejsce w strukturze miasta. Zaważyło to o lokalizacji przy wschodniej krawędzi Błoń reprezentacyjnych budynków, z gmachem Muzeum Narodowego na czele. W 1950 roku zorganizowano konkurs urbanistyczny w związku z planowaną budową kolejnych ważnych obiektów w najbliższej okolicy. Artykuł przedstawia niepublikowane dotąd prace i wpływ rozstrzygnięć tego zapomnianego konkursu na dzisiejsze zagospodarowanie obszaru wokół placu przed Muzeum Narodowym. Celem pracy jest przedstawienie nieznanych prac konkursowych z połowy XX wieku i wykazanie, w jakim stopniu wpływają na rozwiązania przestrzenne terenu na zamknięciu ulicy Piłsudskiego, w okolicy Muzeum Narodowego. W pracy posłużono się analizą porównawczą zachowanych materiałów ikonograficznych i znanych autorowi prac projektowych. Przeprowadzone analizy prowadzą do wniosku, że nie wykorzystano w pełni szans, aby wylot ulicy Piłsudskiego stał się punktem węzłowym w kompozycji urbanistycznej miasta, miejscem integracji przestrzeni po obydwu stronach Alei Trzech Wieszczów. Kluczem dla właściwego rozwiązania przestrzennego placu przed Muzeum Narodowym jest objęcie analizą projektową również terenów po wschodniej stronie Alei Trzech Wieszczów.
Wykorzystanie narzędzi cyfrowych do ulepszenia procesów operacyjnych w przestrzeniach architektonicznych polikliniki szpitalnej
Authors: Saeed Waleed Ben , Adas Yasser , Almaimani Ayad
Published: March 2024

Przestoje są poważnym problemem, który dotyczy procesów operacyjnych poliklinik szpitalnych (PS). Dotyczy on zwłaszcza przestrzeni architektonicznych PS, z uwagi na zwiększoną ilość pacjentów. W ostatnim czasie użyto narzędzi cyfrowych w systemach opieki zdrowotnej, aby zmniejszyć przestoje i ułatwić polepszanie procesów operacyjnych w PS; jednym z takich narzędzi jest wirtualny pokój badań. Niemniej jednak pacjenci wciąż muszą być przebadani przez lekarzy w PS i narzędzia cyfrowe same w sobie nie rozwiążą wszystkich problemów, które powodują przestoje. Autorzy niniejszego artykułu przeprowadzili badanie, które oferuje nowy sposób złagodzenia przestojów w PS poprzez połączenie fizycznych i cyfrowych rozwiązań, które zwiększają sprawność PS i optymalizują procesy operacyjne. Zaproponowano alternatywny plan operacyjny, który dodaje wirtualne pokoje badań celem zmniejszenia przestojów. Plan ten pozwala PS na zwiększenie ilości fizycznych i wirtualnych pokojów badań o niemal 110% oraz na zwiększenie dziennej ilości przebadanych fizycznie i wirtualnie pacjentów o 153%. Plan przewiduje przeprojektowanie wnętrz architektonicznych PS, aby polepszyć środowisko i dostosować szpital do wymogów autoryzowanych instytucji.
Zastosowanie szkła konstrukcyjnego w kształtowaniu przeszklonych elewacji
Authors: Jóźwik Anna
Published: March 2024

Szkło jest znaczącym materiałem w kształtowaniu współczesnej architektury. Główną jego cechą pozostaje transparentność, co wiąże się z możliwością przepuszczania światła dziennego do wnętrza budynku. Szklane elewacje wyznaczają zanikającą granicę między wnętrzem a przestrzenią zewnętrzną, co jest źródłem inspiracji projektowych. Sprzyja temu również rozwój technologii i wiedzy dotyczącej właściwości szkła jako materiału konstrukcyjnego. Celem artykułu jest rozpoznanie i przeanalizowanie możliwości stosowania szkła konstrukcyjnego w przeszklonych elewacjach. W pracy przeanalizowano aspekty technologiczne i konstrukcyjne szkła. Analizy wykonano w oparciu o metodę logicznej argumentacji, metodę porównawczą oraz studium przypadku. Duży wpływ na wyniki pracy miała analiza wybranych realizacji architektonicznych. Na tej podstawie ustalono typologię i charakterystykę rozwiązań projektowych szklanych fasad z zastosowaniem szkła konstrukcyjnego. Głównym kryterium wskazanej typologii było poszukiwanie rozwiązań, w których dąży się do kształtowania całoszklanych samonośnych struktur. Ustalono, że jest to możliwe przy zastosowaniu systemów bezramowych, szklanych żeber, systemów tarczownicowych czy szkła giętego. Projektowanie systemów samonośnych pozwala wyeliminować lub ograniczyć systemy wsporcze z innych materiałów. Dzięki użyciu szkła konstrukcyjnego możliwe jest zatem uzyskanie jednorodnych materiałowo rozwiązań. Rozwiązania te nie tylko koncentrują się na aspektach technologicznych i konstrukcyjnych, ale mają także wpływ na architektoniczną kreację elewacji.
Rola światła dziennego w kształtowaniu przestrzeni: Klasyfikacja tradycyjnych oświetleniowych elementów architektonicznych w budynkach w Iranie
Authors: Ahmadi Mosleh , Sokół Natalia , Francuzik Joanna , Martyniuk-Pęczek Justyna
Published: March 2024

Charakter światła dziennego można zdefiniować jako sposób, w jaki światło dzienne przenika i rozprasza się w przestrzeni. Elementy architektoniczne związane z oświetleniem dziennym, które są badane w tej pracy, mają swoje korzenie w dziedzictwie irańsko-isfahańskim, zwanym tradycyjną architekturą irańską (od XVI wieku do początku XX wieku). Ustalenie systemu klasyfikacji dla systemów oświetlenia dziennego ma znaczące zastosowanie praktyczne. Niniejsza praca ma na celu przedstawienie elementów architektonicznych obecnych w budynkach w stylu isfahańskim, które umożliwiają przenikanie światła dziennego, poprawiając tym samym estetykę wnętrza. Metodologia zastosowana w tej pracy opiera się na subiektywnej obserwacji i dokumentacji fotograficznej. Na podstawie wyników badania elementy architektoniczne oświetlenia dziennego można zaklasyfikować do czterech odrębnych kategorii: „kontrolery”, „rozpraszacze”, „filtry” i „modyfikatory”. System klasyfikacji został opracowany na podstawie zaobserwowanej złożoności zjawiska przenikania światła do wnętrza (zarówno pod względem ilości, jak i jakości efektu wizualnego wywołanego światłem dziennym), funkcji (dotyczących oświetlenia, widoku na zewnątrz lub przesłon), cech materiałowych (w tym przejrzystości, szorstkości i jaskrawości) oraz wpływu na oświetlenie dziennie (takie jak rozkład, odwzorowanie kolorów i intensywność). Kontrolery światła dziennego zawierają elementy takie jak hurno (świetlik), ravaq, sabat i tabesh-band/sarsayeh/kharakpoush (urządzenia przesłaniające), podczas gdy rozpraszacze światła dziennego obejmują shabak, rozan, pachang (okna i drzwi) oraz muqarnas (ozdobna forma świetlika). Filtry światła dziennego, reprezentujące bardziej zaawansowane elementy w porównaniu do dwóch poprzednich kategorii, obejmują goljam (okna) i jam-khaneh (świetliki). Najbardziej skomplikowane elementy manipulacji światłem dziennym to modyfikatory światła dziennego, zilustrowane przez orosi (okna) i roshandan (świetliki).
Hrubieszowskie korzenie w twórczości i działalności Profesora Wiktora Zina
Authors: Makowska Beata Elżbieta
Published: March 2024

Celem artykułu jest prześledzenie związków twórczości i działalności Profesora Wiktora Zina z miejscem jego pochodzenia — Hrubieszowem. Przesłanie Profesora dotyczące potrzeby dokumentowania i ochrony dziedzictwa kulturowego tego regionu nie traci na aktualności, szczególnie obecnie, kiedy stare obiekty drewnianej zabudowy ulegają zniszczeniu. W artykule przedstawiono wnioski, że miejsce urodzenia było ważnym motywem w twórczości i działalności Wiktora Zina. Obok dorobku publikacyjnego i projektowego istotne znaczenie dla ochrony dziedzictwa kulturowego Hrubieszowa miała także popularyzacja tej problematyki w szerszym gronie odbiorców, która jest kontynuowana do dziś.
Mphages and the Blood-Brain Barrier: A Review
Authors: Maľarik Tomáš , Bhide Katarína , Talpašová Lea , Bhide Mangesh
Published: March 2024

The blood-brain barrier (BBB) is a protective barrier that prevents most substances from entering the brain from the bloodstream, including bacteria and viruses. Unfortunately, this restriction also applies to 99.9 % of therapeutics, posing significant challenges in the treatment of brain diseases. Overcoming this barrier is critical for effective treatment of neurological disorders. Several drug delivery systems are being developed to improve transport of therapeutic agent across the BBB. For example, nanoparticles (liposomes, polymeric nanoparticles, dendrimers), nanocarriers (micelles, nanogels), protein-based delivery (penetrating peptides, exosomes), focused ultrasound, and most recently, a filamentous phage based nanocarriers. Filamentous bacteriophages are viruses that infect bacteria and are not designed to infect eukaryotic cells. Recent evidence suggests that filamentous bacteriophages, such as M13, can cross BBB and enter the central nervous system (CNS). Researchers have been investigating the potential use of M13 as drug carriers, including the delivery of therapeutic agents to the brain. This entails modifying the bacteriophages to carry payloads such as drugs and using them as a delivery system. The BBB’s complexity and the potential risks associated with changing it necessitate careful consideration in the development of such strategies. M13 nanocarrier development is ongoing, and advancements may lead to new therapeutic options for treating infections in the CNS. However, it is important to note that this field is still in its infancy, and more research is needed to assess the feasibility and safety of using modified bacteriophages to cross the BBB. This brief review attempts to compile current research on the potential use of bacteriophages for drug transport across the BBB.
Empirical Evidence of ESG Disclosure's Impact on Corporate Investment Decision in Indonesia
Authors: Cahyono Suham , Damayanti Vira Ayu , Ardianto Ardianto , Ardianto Ardianto
Published: March 2024

The purpose of this study is to investigate the impact of environmental, social, and governance (ESG) disclosure on corporate investment decisions. Data were collected from annual reports of firms listed in Indonesia Stock Exchange between 2015 and 2020 (378 firm-year observations). Using Ordinary Least Square (OLS) and fixed effect estimation, this study found that the dimension of ESG practices positively affects corporate investment decisions. In addition, the presidential election periods increase the effectiveness of corporate investment decisions. The study results reveal that uncertainty in the economic and business environment over the impact of general elections increases the company's ability to generate higher investments. This study contributes to the company strategic alignment to justify management about investment prioritize in the stakeholder wealth through ESG disclosure.
Pengembangan Desain Kartu Pembelajaran Berbasis Augmented Reality
Authors: Bahalwan Hamdan , Hidayat M. Junaidi
Published: March 2024

Pandemi sudah merambah ke seluruh dunia. Pandemi merubah tatanan keseharian manusia, mulai dari hal yang kecil sampai pada hal yang krusial. Manusia dituntut untuk beradaptasi dengan pandemi covid-19. Banyak kendala yang dihadapi, salah satunya adalah kesulitan belajar siswa di dunia Pendidikan. Pendidikan jarak jauh yang tidak komunikatif membuat anak sebagai pelajar sukar untuk memahami materi yang diberikan. Terlebih tidak ada inovasi baru dalam pemberian materi oleh pihak sekolah. Melalui metode QFD (Quality Function Development) permasalahan pemebelajaran yang monoton diubah menjadi pembelajaran yang menarik dan menyenangkan, yaitu dengan memanfaatkan teknologi Augmented Reality. Hasilnya adalah pengembangan kartu pembelajaran akan lebih menarik minat dan kesenangan dari siswa sekolah.
Gliptins and acute pancreatitis in patients with type 2 diabetes: a review
Authors: Hakami Fahad
Published: March 2024

Diabetes mellitus is a chronic, metabolic, and complex disease that requires continuous treatment and medical care. Type 2 diabetes (T2DM) is disinfected by dysfunction of beta cells and insulin resistance. Gliptins are oral anti-hyperglycemic agents that control hyperglycemia. Acute pancreatitis (AP) is an acute inflammation that occurs in the pancreas. The correlation between acute pancreatitis and diabetes is complex, and there are many incorporated factors, such as anti-hyperglycemic drugs. The oresnt review aimed at providing an overview of acute pancreatitis and its association with T2DM, gliptins as a treatment for T2DM, and the correlation between AP and gliptins among T2DM patients. Scientific databases were used for searching for articles related to our subject. A variety of keywords were used for the search purpose, including "T2DM, AP, Association, Correlation, Incidence, Prevalence, Gliptin, dipeptidyl-peptidase-4 inhibitors." Articles of relevance included those written in the English language, of any type, and conducted on the current subject. To cover as much of the current topic as possible, the discussion of the review contained three major sections. The first section covered acute pancreatitis and its connection to T2DM. In the second section, gliptin agents, safety, and negative effects were discussed. The third section discussed the correlation between acute pancreatitis and gliptin in T2DM patients. Acute pancreatitis was highly developed among type 2 diabetic patients; however, the correlation between acute pancreatitis and gliptins is controversial.
Smartphone addiction and its implications on psychosocial well-being in Saudi school-age children
Authors: Almuzaini Abdulrahman , Almutairi Abdulaziz , Aljumah Sarah , Alobaishi Reema , Alwayel Zahraa , Alqahtani Turki , Aljumiah Jalilah , Almalki Malik
Published: March 2024

Background: Despite smartphones' compelling qualities and their use to access the online world, it has become an integral part of our lives eventually leading to smartphone addiction in its users, especially children. This study focuses on elaborating on the association between smartphone addiction and sleeping, school performance, and poor psycho-social well-being among Saudi school-age children.
Methods: A cross-sectional study was conducted enrolling a total of 363 subjects through an online survey conducted in different malls in Riyadh city. A cross-section study using a self-administered questionnaire contains specific questions related to smartphone addiction in children. The smartphone addiction proneness scale (SPAP) is used to measure the possibility of being addicted to smartphones. Data analysis was achieved by using Statistical Package for the Social Sciences version 26.
Results: This study found strong correlations between smartphone usage and poor school performance (p < 0.010) and between less sleep and low academic achievement (p < 0.001). Male children had significantly higher scores for smartphone addiction (SPAP) than females (p = 0.023), suggesting males struggle more with planned activities due to smartphone use. Aggressive behavior and poor communication were associated with smartphone usage, but there was no significant difference between genders in this aspect (p = 0.153).
Conclusion: There was evidence that a usage time of smartphones 2> hours a day was linked to poor psychosocial well-being, with no association between smartphone addiction effects and specific gender, more awareness should be raised the parents to limit the excessive usage of smartphones among their children.
Assessment of burn first aid knowledge among the general population of Riyadh, Saudi Arabia
Authors: Alghamdi Bader , AlFihaid Abdullah , Alhazani Saud , AlAmrani Haya , Altoom Faisal , AlQahtani Rayan , AlZimami Mohammed , Almudawi Mohammed , Alokassi Ghala
Published: March 2024

Background: Burn injuries are a prevalent public health concern globally, necessitating effective first-aid practices for optimal outcomes. This study aims to assess the knowledge and practices of adults in Riyadh, Saudi Arabia, regarding first aid for burns, recognizing the importance of understanding current awareness levels and identifying potential areas for targeted interventions.
Methods: A cross-sectional survey design was employed, the study included 388 adults aged 18 and above in Riyadh, utilizing non-probability convenience sampling. A structured questionnaire, developed in Arabic and English, covered demographics, burn causes knowledge and first-aid practices. Statistical analyses, including descriptive statistics and Chi-square tests, were conducted using Statistical Package for the Social Sciences (SPSS) version 26.
Results: This study involved 388 participants and found that the majority (59.3%) were aged 18-29, with 38.1% male and 61.9% female. Furthermore, 81.2% had a university education. Participants showed a strong awareness (89.8%) of hot water as a leading cause of burns, with 93.0% correctly identifying the kitchen as a likely place for burns. Positive practices, like not touching blisters from first-degree burns, were observed in 76.6% of participants. However, misconceptions, such as using ice directly on burned areas (29.9%), were also prevalent. In addition, 33.6% relied on peers, colleagues, or family members for knowledge acquisition.
Conclusion: The study underscores the importance of targeted educational interventions to address knowledge gaps and correct misconceptions related to burn first aid. Emphasizing evidence-based practices, particularly in scenarios where misconceptions exist, can contribute to improved community response to burn injuries. Collaboration with healthcare professionals, leveraging digital platforms, and incorporating community influencers in educational campaigns are recommended strategies.
Screening In Silico Alpha-amylase and Alpha-glucosidase Inhibitory Activity of Flavonoid Compounds for the Treatment of Type 2 Diabetes
Authors: Thanh Tung Bui , Thi Huong Le , Thi Duong Trinh , Thi Huyen Nguyen , Thi Thuy Nguyen
Published: March 2024

Diabetes mellitus (diabetes) is a chronic disease associated with metabolic disorders and hyperglycemia. α-glucosidase and α-amylase, which play an important role in the hydrolysis of starch and carbohydrates, are enzymes. They are related to the increase and decrease in blood glucose levels. Flavonoids are a common group of natural compounds that have been shown to have many beneficial health effects. This study used molecular docking methods and drug-like criteria, predicting pharmacokinetics-toxicity (ADMET) to screen and evaluate potential flavonoid compounds in the treatment of type 2 diabetes. After screening the compounds, we obtained 46 compounds with lower binding energies than the positive controls, which are acarbose. Using Lipinski's rule of five, we evaluated the drug-likeness of the compounds and identified 12 compounds that met the criteria. Then, continuing to analyze according to pharmacokinetic and toxicological parameters (ADMET), we obtained 3 compounds including Galangin, Maackiain, and Corylin, that have the potential to be developed into drugs when showing the ability to simultaneously inhibit both enzymes α-glucosidase and α-amylase have positive properties: binding energy is lower than the control, creates many interactions with target proteins in the active site, has drug-like properties, relatively good pharmacokinetic properties and low toxicity. Therefore, further in vitro and in vivo studies are needed to develop these potential compounds into drugs for the treatment of type 2 diabetes.
Problematika Sertipikat Hak Atas Tanah Yang Hilang Dalam Proses Jual Beli Tanah
Authors: Namira Muna Salsabila  , Dinda Keumala
Published: March 2024

Jual beli tanah baru bisa didaftarkan apabila dilakukan dihadapan PPAT sebab dasar pendaftaran jual beli dari AJB yang dibuat oleh PPAT. Permasalahan dalam tulisan ini adalah Bagaimana tata cara jual beli tanah yang dilakukan pada sertipikat hak atas tanah milik penjual yang hilang dan apa saja kendala serta solusi yang dilakukan PPAT dalam menyelesaikan permasalahan ini. Penelitian ini menggunakan tipe normatif yang sifatnya deskriptif didasari dengan data sekunder berupa Peraturan-Undangan dan literatur serta data primer berupa wawancara. Dianalisa dengan cara kualitatif serta mengambil kesimpulan secara deduktif. Hasil penelitian ini adalah PPAT memproses pembuatan atau penerbitan sertipikat pengganti dan memproses balik nama sertipikat pengganti atau pendaftaran peralihan hak sebab jual beli di Kantor Pertanahan dengan melampirkan persyaratan yang dibutuhkan. Kendala yang dihadapi adalah pembeli tidak dapat menunjukkan sertipikat tanah karena hilang dan tidak diketahui keberadaan penjualnya, tidak mengetahui nomor sertipikat serta waktu yang lama dalam proses penerbitan sertipikat pengganti. Solusi yang dilakukan PPAT mengajukan permohonan ke Kantor Pertanahan untuk melakukan pengukuran ulang bidang tanah, memberitahu pembeli mengajukan gugatan ke Pengadilan Negeri serta memberitahu pembeli untuk sesegera mungkin melakukan balik nama sertipikat.
SANKSI PIDANA TERHADAP IBU KANDUNG YANG MENGAKIBATKAN MATINYA ANAK (STUDI PUTUSAN NOMOR 47.PID.SUS/2021/ PN.JKT.PST)
Authors: Kharisma Nabila Sapeva  , Maria Silvya E. Wangga
Published: March 2024

This research is about criminal sanctions imposed on biological mothers who act violently against their children by hitting them, resulting in the child's death. By reviewing decision No.47/Pid.Sus/PN.JKT.PST, the formulation of the research problem is whether the judge considers the punishment of the biological mother based on Article 80 paragraph (3) in conjunction with Article 76 C of Law no. 35 of 2014 in Decision no. 47/Pid.Sus/2020/Pn.Jkt is in accordance with the theory of the purpose of punishment. This research is of a normative juridical type which is descriptive in nature, through the use of secondary data with qualitative processing and drawing conclusions deductively. The results of his research showed that the judge did not consider the formulation of norms in Article 80 paragraph (3) in conjunction with Article 76 C of Law no. 35 of 2014 concerning child protection, namely the punishment increased by 1/3 so that the prison sentence for the perpetrator becomes 20 years. The conclusion from this research is that considering the sanctions that the judge imposed for the punishment of the biological mother in Article 80 paragraph (3) in conjunction with Article 76 C of Law no. 35 of 2014 does not match the theory of the purpose of punishment based on contemporary theory
KAJIAN YURIDIS PENANGKAPAN lKAN MENGGUNAKAN BAHAN PELEDAK (STUDI KASUS NELAYAN DI MUARA ANGKE JAKARTA UTARA)
Authors: Aulia Atasya Hidayat  , Dyah setyorini
Published: March 2024

Catching fish with fishing gear that uses materials or chemicals in marine waters is a practice that can have a negative impact on the safety of marine ecosystems. Additionally, it can lead to damage to coral reefs in Indonesian marine waters. The research is conducted in a normative manner on the fundamental legislative regulations. Furthermore, direct interviews are conducted with fishermen in North Jakarta's Muara Angke. Data processing is carried out qualitatively, and conclusions are drawn using deductive methods. The problem in this research is: What are the policies regarding fishing gear in the Fisheries Law and its implementing regulations, and what are the reasons behind fishing activities carried out by fishermen using explosives (a case study of fishermen in North Jakarta's Muara Angke)? The act of catching fish with explosives falls under the definition of illegal fishing because it contradicts the laws of a country or international regulations. The reason behind fishing with explosives is economic factors because the price of explosives is relatively cheap and easy to find
LAHAN SAWAH DILINDUNGI DIKAITKAN DENGAN RENCANA TATA RUANG BERDASARKAN PERATURAN PRESIDEN NOMOR 59 TAHUN 2019
Authors: Diah NikenSari  , Meta Indah Budhianti
Published: March 2024

Perubahan alih fungsi lahan sawah di Indonesia seringkali berubah menjadi lahan non pertanian seperti pembangunan pemukiman atau ditetapkan sebagai proyek strategis. Hal ini berdampak serius dan mengancam ketahanan pangan nasional. Rumusan masalah yaitu Apakah Rencana Tata Ruang Lahan Sawah Dilindungi Sudah Sesuai Peraturan Presiden Nomor 59 Tahun 2019. Metode penelitian secara normatif dengan sifat penelitian deskriptif analitis menggunakan jenis data sekunder dan data primer, analisis data secara kualitatif, pengambilan kesimpulan dengan logika deduktif. Adapun hasil penelitian pembahasan tidak semua penetapan Lahan Sawah Dilindungi sesuai dengan Rencana Tata Ruang, miskomunikasi terkait data lahan yang tidak dilaporkan menjadi bentuk kendalanya sehingga upaya yang dapat dilakukan Kementerian ATR/BPN yakni melakukan pembinaan kepada para stakeholder. Dari penelitian dapat disimpulkan penetapan lahan sawah dilindungi dikaitkan dengan rencana tata ruang masih belum sesuai dengan Peraturan Presiden Nomor 59 Tahun 2019 karena masih ditemukan kendala dalam penetapan LSD dimana Pemerintah Pusat dan Pemerintah Daerah mempunyai wewenang tersendiri yang membatasi ruang gerak Pemerintah Pusat dalam melakukan penetapan atas Lahan Sawah Dilindungi.
PERBANDINGAN HUKUM JUAL BELI TANAH DI INDONESIA DAN RUSIA
Authors: Mohammad Rafli  , Sri Untari Indah Artati
Published: March 2024

Comparative law is the activity of comparing laws from various countries, the purpose of which is to contribute to the development of new laws and regulations or their amendments and find how similarities and differences in concepts, legal institutions that contribute, legal systems used. In Indonesia, land law is regulated in Law Number 5 of 1960 concerning Basic Regulations on Agrarian Principles, hereinafter referred to as UUPA, while in Russia land law is regulated in The Land Of Code Russia No. 136-FZ of 2001. The formulation of this research problem is how are the similarities and differences in the regulation of buying and selling land in Indonesia and Russia, the research method uses normative juridical type, the nature of descriptive research is sourced from secondary data, the research data is analyzed qualitatively and the conclusion is drawn using deductive. In addition, there are differences in the sale and purchase of land in Indonesia and Russia, namely the regulation of land sale and purchase, the meaning of land, the object of land sale and purchase, the transfer of rights from the seller to the buyer, the initial agreement, the parties authorized to make the agreement.
Prototype Design of a Fishing Boat Safety Monitoring System Using LoRa and Microsensor Devices
Authors: Sugiarto Eka , Suhendi Asep , Abdussalam M. Yusup , Husniah Zahira Aulia , Lestari Annisa Puji
Published: March 2024

This paper reports a prototype of a low-cost tracking and monitoring system to address the challenges faced by Indonesian fishermen. The lack of safety equipment in their boats exposes them to high risks of work-related accidents and illnesses. Data from the National Basarnas Center reveals a staggering 24,000 annual fatalities among fishermen during their activities. These issues stem from a combination of factors: poorly designed boats, low prioritization of safety, and the lack of readily available preventive measures. Moreover, the development of telecommunications infrastructure in aquatic areas presents its unique obstacles. In response, this study proposes a prototype design for a "Fishing Boat Safety Monitoring System" utilizing LoRa and Microsensors for proactive and preventive measurement by tracking the boat position and sending the data via a long-distance wireless transmission with Low-Power Wide Area Network (LPWAN) scheme based on frequency-spread spectrum technology. This LPWAN serves as the substitution for cellular network which is usually not available in the ocean. The tracking system uses a low-cost TTGO T-Beam LoRa32 V1.1 Microcontroller Unit (MCU) board that has an embedded SX1276 LoRa module and Neo-6M GPS module. The system also uses a GY-25 gyroscope microsensor. The system implemented a 923 MHz LoRa signal for point-to-point communication between the transmitter to receiver. This research has successfully yielded a developed device capable of tracking the location of boats up to 2 km from the shoreline with -113 dBm received signal strength indicator (RSSI) and around 60% of data quality of service (QoS). Further research will explore the use of high-gain antennas and signal amplifiers integration with embedded LoRa on the MCU board to expand the coverage area of the LoRa signal.
Index and Back Cover
Authors: Purbosari Lina
Published: March 2024

Index and Back Cover
Spontaneous thrombosis and calcification of giant cavernous carotid artery aneurysm: A rare case and management insights
Authors: Jha Vikas Chandra , Jain Rahul , Sinha Vivek Saran , Kumar Nitish , Verma Gaurav , Dhage Nikhil
Published: March 2024

Background:

Giant cavernous carotid artery aneurysms (>25 mm) are rare (3–5%), with some prone to spontaneous thrombosis (10–20% complete). We present a unique case of one of the largest aneurysms spontaneously thrombosing and calcifying.

Case Description:

A 57-year-old with persistent right-sided headaches had a substantial hyperdense mass in the right middle cranial fossa, eroding petrous bone. Magnetic resonance imaging and digital subtraction angiography revealed a giant cavernous segment fusiform aneurysm of the right internal carotid artery (ICA) with spontaneous thrombosis and distal ICA occlusion. Collateral circulation maintains the cerebral blood supply. Despite anatomical challenges, conservative management was chosen due to the patient’s stability.

Conclusion:

This case highlights the complex interplay between thrombosed giant aneurysms and affected vessels, with unique features such as cross-flow, calcification, and bone erosion. We advocate conservative management for stable cases, supported by literature, emphasizing vigilant follow-up. This expands the spectrum of aneurysm presentations and encourages further research into their dynamics.
Correlation of cerebral microvascular circulation with vital signs in cerebral compression and the validity of three concepts: vasodilation, autoregulation, and terminal rise in arterial pressure
Authors: Hekmatpanah Javad
Published: March 2024

Background:

Vasodilation, autoregulation, and rising arterial pressure are three common concepts in cerebral compression, believed to improve cerebral blood flow to maintain the brain’s nutrition. However, these concepts are unclear, unproven, and based on assumptions. This study aimed to correlate cerebral circulation with alterations of vital signs and to evaluate the above concepts based on physics and hemodynamics.

Methods:

Without new animal experiments, a large amount of data: recording of vital signs, long movies of cerebral circulation, and numerous photos of histological examination and microvessels obstruction in cerebral compression in cats was studied, and only partial and preliminary results were reported in 1970. The experiments were supported by an NIH grant for head injury, done before the 1985 Institutional Animal Care and Use Committee requirement. The advent of digital technology facilitated digitizing and stepwise correlating them and evaluating the validity of the above concepts.

Results:

As cerebral compression increased intracranial pressure (ICP), veins dilated, not arteries, and arterial microvessels obstructed, diminished, and stopped cerebral circulation. Simultaneously, vital signs deteriorated, and pupils became fixed and dilated. There was no evidence for what is believed as autoregulation.

Conclusion:

In cerebral compression, rising ICP obstructs cerebral arterial microvessels while simultaneously deteriorating vital signs. There is no evidence for dilatation of the arteries; only veins dilate, best-called venodilation. There is no evidence of autoregulation; what occurs is a cerebral compartmental syndrome. The terminal rise of arterial pressure is the hemodynamic result of cerebral circulation cessation, overloading the aorta. None of the concepts benefit the brain’s nutrition.
Prognostic risks of venous thrombosis in children
Authors: Евстратов Д.А. , Жарков П.А. , Румянцев А.Г.
Published: March 2024

Венозные тромбозы (ВТ) являются серьезной проблемой у детей и взрослых, так как могут приводить к различным осложнениям и даже к смерти. В детской популяции ВТ является относительно редким заболеванием и в большинстве случаев ассоциирован с другими фоновыми состояниями, такими как злокачественные новообразования, инфекционные заболевания, травма, оперативные вмешательства, но наиболее частым фактором риска развития ВТ у детей является наличие центрального венозного катетера. Выявление групп риска тромбозов и проведение первичной антитромботической профилактики снижает этот риск. Клиницисты-педиатры нуждаются в выявлении групп риска развития ВТ, в связи с чем ведется практическая разработка прогностических моделей риска ВТ. Однако данные модели нуждаются в валидации.

Venous thromboembolism (VTE) is a significant issue for both children and adults and can lead to severe complications and even death. VTE is a rare condition in pediatric populations, mostly occurring as a result of underlying conditions such as cancer, infectious diseases, trauma, or surgical procedures. The most important risk factor, however, is the central venous catheter. Identified high-risk groups for VTE can improve survival rates. In the pediatric setting, physicians require a prognostic tool to ascertain patients at high risk for VTE.
FIB’n’SIMS – Advanced Depth Analysis on Hybrid Organic-Inorganic Nanomaterials
Authors: Hartwich Patrick , Naidu Vakamulla Raghu Swathi , Mogwitz Boris , Onyenso Gabriel , Rohnke Marcus , Killian Manuela S.
Published: March 2024

The analysis and characterization of hybrid organic-inorganic metal oxide nanomaterials is of huge interest nowadays, due to their vastly increased use in current-issue applications reaching from solar energy conversion to catalysis or medical applications. Common to all, those hybrid materials are backboned by nanostructured metal oxides which contain modifications like self-assembled monolayers or molecule (e.g., drug) loadings leading to complex functional composite materials. While the chemical composition analysis or morphological studies of such structures can be performed superficially for example with time-of-light secondary ion mass spectrometry (TOF-SIMS) or scanning electron microscopy (SEM) respectively, a proper and efficient way for gathering depth information of such a composite material with appropriate resolution and measurement time has not yet been developed. Depth analysis by common sputtering techniques may lead to artefacts and destruction of molecular information during the analysis and, thereto, in a loss of signal. To overcome these issues in in-depth characterization of interlaced organic-inorganic nanostructures, this study presents the possibilities given by use of time-of-flight secondary ion mass spectrometry (TOF-SIMS) alone and in combination with cross-section-polishing (CSP) or focused-ion-beam (FIB) milling. A correlation in-between those methods is demonstrated on a model zirconium dioxide nanostructure-based material and a complex model consisting of encapsulated dye sensitized solar cells based on titanium dioxide nanotubes.
Diversification of pharmaceutical manufacturing processes: Taking the plunge into the non-PGM catalyst pool
Authors: Zhao Hui , Ravn Anne , Haibach Michael , Engle Keary , Johansson Seechurn Carin
Published: March 2024

Recent global events have led to the cost of platinum group metals (PGMs) reaching unprecedented heights. Many chemical companies are therefore starting to seriously consider and evaluate if, and where, they can substitute PGMs for non-PGMs in their catalytic processes. This review covers recent large-scale applications of non-PGM catalysts in the modern pharmaceutical industry. By highlighting these selected successful examples of non-PGM-catalyzed processes from the literature, we hope to emphasize the enormous potential of non-PGM catalysis and inspire further development within this field to enable this technology to progress towards manufacturing processes. We also present some historical context and review the perceived advantages and challenges of implementing non-PGM catalysts in the pharmaceutical manufacturing environment.