bluuebunny/crossref_metadata_2025 huggingface dataset:
Are there differences in nutrient intake of Brazilian adults according to weight status?
Authors: Araujo Marina Campos , Estima Camilla de Chermont Prochnik , Yokoo Edna Massae , Lopes Taís de Souza , Pereira Rosangela Alves , Sichieri Rosely
Published: July 2019

Abstract It was assessed the intake and prevalence of inadequate nutrient intake according to weight status among Brazilian adults from urban areas (n=16,198) evaluated in the Brazilian National Dietary Survey (NDS – 2008-2009), that obtained food records from two non-consecutive days. The prevalence of inadequate nutrient intake according to weight status was estimated based on Brazilian and international recommendations, in which usual intake was estimated applying the National Cancer Institute method. From 14 nutrients evaluated, six differed according to weight status in men, and only two among women. For men, the mean proportion of energy derived from lipids and saturated fat and mean intake of cholesterol, zinc, and vitamin B12 were greater among those with excess weight compared to those with normal weight; the inverse was observed for dietary fiber. Mean sodium intake was greater and proportion of energy from added sugar intake was lower among obese women compared to overweight ones. Strategies to encourage food consumption with high micronutrient density should be targeted to adult population regardless of their weight status.
Os “problemas de pressão” na Guariroba/DF, Brasil: um aporte da antropologia para pensar doenças crônicas cardiovasculares
Authors: Fleischer Soraya
Published: July 2019

Resumo Este artigo pretende, a partir da Antropologia, apresentar dados etnográficos construídos no bairro da Guariroba/DF. Entre 2008 e 2014, moradores, em geral sexagenários, migrantes e de classe popular, compartilharam suas percepções sobre o que chamavam de pressão alta e problema de pressão, como os sentiam, explicavam e tratavam. A relação estreita e significativa entre a pressão e os nervos surgiu claramente e ajuda a balizar a dificuldade que os profissionais de saúde e os pesquisadores da área têm em considerar essa relação. Sugiro que considerar essa relação tanto aprimorará a prática clínica e farmacêutica quanto os resultados científicos sobre a hipertensão arterial. Conhecer as percepções em primeira pessoa, de quem experiencia adoecimentos prolongados e crônicos, é uma medida relevante para modular mais estrategicamente as ações de prevenção e cuidado.
Desigualdades regionais e sociais em saúde segundo inquéritos domiciliares (Brasil, 1998-2013)
Authors: Viacava Francisco , Porto Silvia Marta , Carvalho Carolina de Campos , Bellido Jaime Gregório
Published: July 2019

Resumo Este artigo busca discutir a evolução das desigualdades em saúde e no acesso aos serviços de saúde nas grandes regiões a partir de inquéritos domiciliares realizados de 1998 a 2013. As desigualdades sociais foram analisadas pelas razões de extremos de anos de escolaridade, considerando duas faixas etárias (18 a 59 anos e 60 anos ou mais). Nas condições de saúde, observa-se, nos dois grupos etários, uma pior avaliação do estado de saúde e um aumento da prevalência de diabetes e hipertensão, o que pode estar relacionado à expansão da atenção básica. Quanto à realização de consultas médicas no último ano, encontra-se, no geral, maior acesso, com manutenção de pequenas desigualdades. A maior utilização de consulta odontológica entre os de menor escolaridade provoca uma redução nas desigualdades, que ainda são significativas. As internações hospitalares, ao longo da série, são maiores entre os menos escolarizados, e há uma redução nas taxas nos dois grupos etários, em quase todas as regiões. Percebe-se um aumento na realização de mamografia por mulheres menos escolarizadas, com diminuição da desigualdade. Os resultados corroboram a necessidade da continuidade dos inquéritos domiciliares para o monitoramento das desigualdades regionais e sociais no acesso ao sistema de saúde.
Renúncia, violência e denúncia: representações sociais do homem agressor sob a ótica da mulher agredida
Authors: Nóbrega Vannucia Karla de Medeiros , Pessoa Júnior João Mário , Nascimento Ellany Gurgel Cosme do , Miranda Francisco Arnoldo Nunes de
Published: July 2019

Resumo Objetiva-se analisar as representações sociais do comportamento agressivo do homem sob a ótica da mulher agredida. Trata-se de um estudo de natureza qualitativa e representacional realizado com vinte mulheres que estavam sob proteção do Centro de Referência de Natal/RN, tendo como instrumento de coleta de dados a narrativa livre. Para a análise dos dados textuais, optou-se pelo uso do software ALCESTE 2010. Elaboraram-se três categorias de temáticas: i) O aprisionamento da mulher; ii) A violência e suas significações; iii) A ruptura do ciclo violento. As representações sociais do comportamento agressivo do homem sob a ótica da mulher agredida estão ancoradas nos papéis sociais do homem na família e na sociedade. Assim, configura-se um modelo de masculinidade dominante que reforça, construções familiares e repetições de papéis.
Caregiver’s oral health literacy is associated with prevalence of untreated dental caries in preschool children
Authors: Montes Gisele Ristow , Bonotto Danielle Veiga , Ferreira Fernanda Morais , Menezes José Vitor Nogara Borges , Fraiz Fabian Calixto
Published: July 2019

Abstract The aim of this study was to evaluate the relationship between oral health literacy (OHL) among caregivers and untreated dental caries among preschoolers. A cross-sectional study was conducted involving 415 preschool children and their caregivers from Curitiba, Brazil. The children were examined for dental caries and dental plaque. The caregivers’ OHL was evaluated using an instrument translated and validated for Brazilian Portuguese: the Brazilian Rapid Estimate of Adult Literacy in Dentistry-30. The prevalence of children with untreated caries was 42.9% (95%CI: 38.1-47.7%). A low degree of OHL was found among 15.7% (95%CI: 12.2-19.2) of caregivers. The multivariable Poisson regression analysis indicated a higher prevalence of untreated caries among children whose caregivers had a low OHL (PR = 1.35; 95% CI: 1.01-1.79), those with visible plaque (PR = 1.28; 95% CI: 1.01-1.62) and those who never or only occasionally had their teeth brushed by their caregivers (PR = 1.48; 95% CI: 1.16-1.91) in comparison to those without these conditions. In conclusion, a higher prevalence of untreated dental caries was found among preschool children whose caregivers had a low degree of OHL.
Effects of pesticides on rural workers: haematological parameters and symptomalogical reports
Authors: Dalbó Juliana , Filgueiras Lívia Alves , Mendes Anderson Nogueira
Published: July 2019

Abstract Exposure to pesticides by the rural population is increasing worldwide. Pesticides can induce the development of different diseases such as cancer and diseases of the central nervous system. This study analysed the clinical symptoms and haematological changes of a rural population in Conceição do Castelo, Espirito Santo, Brazil. For evaluation of symptomatology exposure to pesticides, 142 rural workers were interviewed. Of these, 22 workers were selected for haematological tests randomly as to evaluate haematological changes during the period of exposure to pesticides. Haematological analyses showed that erythrocytes, haemoglobin, haematocrit, mean corpuscular (VCM) volume, mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC) are in accordance with the reference intervals in haematology. Variations in the concentrations of rods and neutrophils indicates that exposure to pesticides increases the amount of those cells. Haematological disorders in rural workers exposed to pesticides can be correlated with reported symptoms. The results described in this study are relevant to the health public and reinforce the concern about the indiscriminate use of pesticides.
Barreiras percebidas para o consumo de frutas e de verduras ou legumes em adultos brasileiros
Authors: Santos Graziela Maria Gorla Campiolo dos , Silva Ana Maria Rigo , Carvalho Wladithe Organ de , Rech Cassiano Ricardo , Loch Mathias Roberto
Published: July 2019

Resumo Buscou-se verificar a associação entre barreiras percebidas para o consumo de frutas (CF) e de verduras ou legumes (CV/L) com características demográficas. Foi realizado estudo transversal (n = 877 pessoas com ≤ 44 anos de Cambé/PR). Investigaram-se 5 barreiras para o CF e CV/L. Foi utilizada análise de regressão logística binária ajustada para variáveis demográficas. “Custo pesa no orçamento familiar” foi a barreira mais prevalente (CF 57,7%; CV/L 49,9%), com maior chance da barreira no CF nas mulheres e pessoas com menor escolaridade (0 a 4 anos de estudo) e no CV/L nas mulheres, pessoas com menor escolaridade e de nível econômico B/C. A prevalência da barreira “Família não tem hábito”, foi de 16,4% para CF e 10,9% no CV/L, com maior chance para pessoas com 50 a 59 anos no CF. “Falta de tempo para comprar alimentos frescos”, foi citada por 8,0% (CF) e 7,6% (CV/L), com maior chance da barreira no CF em mulheres e indivíduos sem companheiro. A barreira “Necessidade de preparo” teve prevalência de 7,6% para CF, com maior chance para pessoas com idade entre 44 e 59 anos e no CV/L (9,7%), maior nas mulheres. A prevalência de “Não gostar do sabor” foi de 6,2% para o CF e 6,6% CV/L, e observou-se maior chance nos negros/pardos/indígenas (para CV/L).
Análise sobre a constituição de uma rede de Saúde Mental em uma cidade de grande porte
Authors: Almeida Isabella Silva de , Campos Gastão Wagner de Sousa
Published: July 2019

Resumo Este artigo se propôs a refletir sobre a constituição das redes de atenção psicossocial, a partir de um território do município de São Paulo. Para tanto, foi realizado um estudo exploratório sobre o SUS e a Saúde Mental no município no período de 1980 a 2013. Foram feitas leituras de documentos oficiais e artigos, dissertações, teses e livros sobre a implementação do SUS na cidade de São Paulo, com ênfase na rede de saúde mental. Realizou-se ainda a escuta de atores que viveram parte dessa história, a partir de entrevistas abertas. Dessa forma, foi possível pontuar seis marcos: modelo assistencial asilar-manicomial; década de 1980: avanços e retrocessos; 1989 – 1992: modelo de atenção integral à Saúde Mental; 1993 – 2000: Retrocessos políticos e resistências; Projeto Qualis II; municipalização da saúde. Com essa leitura analítica, constatou-se a importância dos eventos históricos na compreensão das proposições políticas e na consolidação das políticas públicas, acerca do SUS São Paulo.
Consumo de alimentos preditores e protetores de risco cardiovacular por hipertensos do estado de Alagoas, Brasil
Authors: Ferreira Raphaela Costa , Vasconcelos Sandra Mary Lima , Santos Ewerton Amorim dos , Padilha Bruna Merten
Published: July 2019

Resumo O presente artigo teve como objetivo avaliar o consumo de alimentos protetores e preditores de risco cardiovascular (CV) e sua relação com fatores de risco cardiovascular (FRCV) por hipertensos do estado de Alagoas. Estudo transversal, de base populacional, com 655 adultos, hipertensos, de ambos os sexos, estudados no período de 2013 a 2016. O consumo alimentar foi avaliado por um questionário de frequência alimentar validado com mensuração convertida em escores e os alimentos foram divididos em três grupos: I - processados/preditores de risco CV; II - ultraprocessados/maiores preditores de risco CV; III - alimentos in natura ou minimamente processados/protetores de risco CV. Foram também analisadas variáveis socioeconômicas, demográficas, bioquímicas, clínicas e antropométricas. Os escores de consumo dos grupos de alimentos I, II e III foram, respectivamente, 0,11; 0,13 e 0,24 (p = 0,001). O consumo de alimentos processados se correlacionou positivamente com o colesterol sérico elevado (p = 0,045) e negativamente com a idade (p = 0,001); já o de alimentos ultraprocessados correlacionou-se com o sedentarismo (p = 0,01). Assim, observou-se relação entre o consumo de alimentos preditores de risco CV com sedentarismo e colesterol elevado, refletindo a necessidade de ações de educação nutricional.
Satisfação profissional e sobrecarga de trabalho de enfermeiros da área de saúde mental
Authors: Oliveira Jacqueline Flores de , Santos Alessandro Marques dos , Primo Luciene Smiths , Silva Mara Regina Santos da , Domingues Eliana Soares , Moreira Fernanda Pedrotti , Wiener Carolina , Oses Jean Pierre
Published: July 2019

Resumo Avaliar a satisfação profissional e a sobrecarga de trabalho dos enfermeiros atuantes em serviços de saúde mental e realizar uma comparação em relação aos demais profissionais do serviço. Estudo transversal, com amostragem por critério de conveniência, realizado em 2016 com 61 profissionais da área de saúde mental dos Centros de atenção psicossocial de um município localizado no extremo sul do Brasil. Para coleta de dados foi aplicado um questionário sociodemográfico e as Escalas de avaliação do impacto do trabalho (Impacto-Br) e de satisfação da equipe (Satis-Br). A análise dos dados foi realizada através do programa SPSS 21.0.O nível de sobrecarga global dos enfermeiros foi de 2,92 ± 0,42 e de satisfação global de 3,38 ± 0,51. Quando avaliado os escores na escala Satis-Br, houve uma diminuição estatisticamente significativa nos níveis de satisfação dos enfermeiros (3,36 ± 0,77) em relação aos demais profissionais atuantes no serviço (3,78 ± 0,56) no escore qualidade dos serviços oferecido (p = 0,04). O fator que promoveu maior nível de sobrecarga de trabalho entre os enfermeiros estão relacionados ao sentimento de se sentir fisicamente cansado (2,99 ± 0,92). Já o fator que promoveu maior satisfação profissional está relacionado ao bom relacionamento com a equipe (4,06 ± 0,65).
Perfil dos municípios brasileiros, a presença de tuberculosee sua forma drogarresistente
Authors: Jacobs Marina Gasino , Pinto Junior Vitor Laerte
Published: July 2019

Resumo A tuberculose tem estreita relação com as condições de vida das pessoas. O presente estudo classifica os municípios brasileiros de acordo com a presença ou ausência de casos de tuberculose (TB) e sua forma drogarresistente (TB-DR), e os descreve quanto às condições de saúde da população, os indicadores de controle da tuberculose, perfil demográfico e socioeconômico. Em 2014, 327 municípios registraram casos de TB-DR. Regiões integradas de desenvolvimento ou regiões metropolitanas concentraram 80,1% dos casos de TB-DR do País. Os municípios com casos de TB-DR tiveram piores indicadores de desfecho da TB, mas maiores percentuais de realização de exame de cultura, além de mais habitantes e melhores indicadores socioeconômicos. Os 3.644 municípios com casos de TB, mas sem casos de TB-DR, tiveram os piores indicadores socioeconômicos entre os três grupos. Os 1.594 municípios sem casos de TB tiveram as menores taxas de desemprego e de detecção de AIDS, e maior cobertura de atenção básica. Os diferentes perfis encontrados no estudo podem dar suporte à lapidação de estratégias nacionais de controle da doença e sua forma drogarresistente no País.
Instrumentos de avaliação cognitiva utilizados nos últimos cinco anos em idosos brasileiros
Authors: Martins Núbia Isabela Macêdo , Caldas Priscila Romão , Cabral Etenildo Dantas , Lins Carla Cabral dos Santos Accioly , Coriolano Maria das Graças Wanderley de Sales
Published: July 2019

Resumo A detecção e o monitoramento do déficit cognitivo em idosos são necessários já que podem causar impacto em sua funcionalidade. O objetivo dessa revisão integrativa é analisar a produção científica sobre uso de instrumentos de avaliação cognitiva em idosos brasileiros por meio de artigos publicados nos últimos cinco anos, indexados nas bases de dados Web of Science, PubMed, Scopus e Bireme. Os critérios de inclusão foram: artigos originais publicados em inglês e português, de 2012 a 2016, com critério de idade definido para ser considerado idoso, e escore maior que 6 no CASP adaptado. O critério de exclusão foi: ser resumo de congresso. A amostra final foi composta por 100 artigos. Foram apresentados os 61 instrumentos de avaliação cognitiva utilizados nos estudos, com destaque para o Mini Exame do Estado Mental. Essa revisão apresenta o uso de instrumentos cognitivos na pesquisa brasileira, suas diferentes versões e quais domínios são avaliados. O número de instrumentos presentes na literatura foi amplo. Os mais utilizados foram o MEEM (versão de Brucki e colaboradores), o Teste de Fluência Verbal (categoria animais) e o Teste Span de dígitos (ordem direta e inversa). Os achados apresentados nessa revisão são relevantes não apenas para área da pesquisa observacional e experimental, mas também para a prática clínica.
Fatores associados à adesão à Terapia Antirretroviral em adultos: revisão integrativa de literatura
Authors: Carvalho Patrícia Paiva , Barroso Sabrina Martins , Coelho Heloisa Correa , Penaforte Fernanda Rodrigues de Oliveira
Published: July 2019

Resumo A AIDS é uma manifestação clínica avançada da infecção pelo HIV. Gera imunodeficiência grave e inúmeras infecções associadas, podendo levar à morte. A disponibilidade da Terapia Antirretroviral (TARV) diminuiu a morbi-mortalidade do HIV/AIDS, mas seus benefícios dependem da adesão ao tratamento. Esta revisão integrativa da literatura seguiu a estratégia PICO para identificar os fatores associados à adesão à TARV em adultos. Foram consultadas as bases Medline, SciELO, Lilacs e PePSIC e incluídos artigos publicados entre janeiro de 2010 e dezembro de 2016. Foram analisados 125 artigos, quanto às características dos estudos, medidas de adesão e fatores associados. Os resultados mostraram grande variação na definição da adesão e no uso das medidas para seu monitoramento, além de inúmeros fatores associados à adesão. Os quais foram agrupados nas categorias: 1. variáveis individuais; 2. características do tratamento; 3. características da infecção pelo HIV/AIDS; 4. relação com o serviço de saúde e 5. apoio social. É importante que os serviços caracterizem o perfil dos usuários, sistematizem as medidas de adesão e avaliem regionalmente fatores associados à adesão, para a detecção precoce da não adesão à TARV e estabelecimento de planos efetivos de intervenção.
Indigenous homicide in Brazil: geospatial mapping and secondary data analysis (2010 to 2014)
Authors: Wanzinack Clóvis , Signorelli Marcos Claudio , Shimakura Silvia , Pereira Pedro Paulo Gomes , Polidoro Mauricio , Oliveira Lilian Blanck de , Reis Clóvis
Published: July 2019

Abstract This study aimed to describe a panorama of Indigenous homicide in Brazil, analysing the main characteristics and territorial distribution between 2010 and 2014. Demographic study of Indigenous population data obtained from the Brazilian Institute of Geography and Statistics and Indigenous homicide data (2010-2014) from the Ministry of Health. Data were analysed using descriptive statistics, victims’ characteristics, type of homicides and geographical distribution, which were then plotted on maps using ArcGIS. Findings revealed: 1) a national estimated average of Indigenous homicide rate of 22.5 per 100,000 Indigenous inhabitants per year; 2) a map showing where homicides were registered and the mean homicide rates for Brazilian regions and states, with highest rates in Roraima and Mato Grosso do Sul; 3) the main homicide method were sharp or penetrating objects; 4) Indigenous male homicide rate was 2.4 times higher than female, but Indigenous female rate was more than double that of non-Indigenous; 5) high homicide rates of Indigenous children (under 1-year-old) in areas of the states of Roraima and Amazonas. We advise careful consideration of Indigenous cultural beliefs to avoid errors of judgement, reflecting how Indigenous populations are at risk of homicide in some areas.
Fatores associados à introdução precoce de alimentos ultraprocessados na alimentação de crianças menores de dois anos
Authors: Giesta Juliana Mariante , Zoche Ester , Corrêa Rafaela da Silveira , Bosa Vera Lucia
Published: July 2019

Resumo O objetivo deste artigo é verificar a associação entre fatores maternos e antropométricos e o consumo de alimentos ultraprocessados em crianças de 4 a 24 meses de idade. Métodos: Estudo transversal, com 300 crianças internadas em um hospital terciário e suas mães. A entrevista deu-se nas primeiras 72 horas de internação para evitar interferência nas respostas sobre a alimentação da criança. Os fatores maternos investigados foram: idade, escolaridade, renda, paridade, IMC e orientação sobre alimentação complementar. As variáveis referentes às crianças investigadas foram: idade, aleitamento materno, escola infantil, IMC/idade, estatura/idade, peso/idade e introdução de alimentos ultraprocessados. A associação entre os fatores estudados e a introdução de alimentos ultraprocessados foi testada por regressão linear. O nível de significância considerado foi de 0.05. Verificou-se que apenas 21% das crianças ainda não haviam recebido nenhum tipo de alimento ultraprocessado, sendo que 56.5% recebeu algum destes alimentos antes dos seis meses. Na análise multivariada, escolaridade materna, renda familiar, idade materna e paridade foram associadas à oferta de alimentos ultraprocessados. As práticas alimentares de crianças entre 4 e 24 meses estão inadequadas frente às recomendações para a faixa etária.
Emília, a cidadã-modelo soviética: Como a obra infantil de Monteiro Lobato foi traduzida na URSS
Authors: Darmaros Marina Fonseca , Milton John
Published: July 2019

RESUMO Este artigo analisa a tradução feita na União Soviética de As Reinações de Narizinho (1961) Orden jioltogo diatla (1961) (em português, “Ordem do Pica-Pau Amarelo”), que também inclui trechos de Memórias de Emília. Para ser publicada a tradução teve que sofrer várias mudanças: referências à propriedade particular foram alteradas; o comportamento das personagens ganhou tom educacional e moralizante; críticas aos historiadores e filósofos foram cortadas; e comentários sobre Tia Nastácia hoje em dia considerados racistas precisaram ser amenizados. Além disso, todas as referências às figuras hollywoodianas que visitam o sítio foram omitidas.
Verbal-Visual Mediation: cultural artifacts of power and control for studies of school context in Applied Linguistics research
Authors: Tanzi Neto Adolfo
Published: July 2019

ABSTRACT In this article we explore the data and theoretical discussions of a larger research (Tanzi Neto, 2016, 2017) and present one of the analysis tools of the research group NUVYLA-CNPq (Nucleus of Studies and Research of Vygotsky School in Applied Linguistics), created in 2018. In the framework of a dialogue between Vygotsky, Bakhtin and Bernstein, the research group seeks to demonstrate how the dimensions of verbal-visual utterances (artifacts) practiced in school spaces - embedded of multiple languages - mediate the formation of human consciousness. For this discussion, we analyze the verbal-visuality of different exhibitors from two public school contexts in Brazil. In the first one, of social base of more hierarchical discursive relations, that is to say, of verbal-visual utterances more controlled, the school space is not seen, by its participants, as a place to reach new projects of life, neither as a space of belonging or as recognized social positionings. In the second context, of social base of less controlled relations of power and control, that is, that provides the voice, identity and social position of its participants, we observe a reconfiguration of the dialogical and axiological positions of its participants, creating a school social context of belonging and recognition of its members to achieve future projects.
Braquistócrona na esfera
Authors: Ferreira Rafael Xavier Deiga , Salazar Hector Leny Carrion
Published: July 2019

Abstract O problema consiste em determinar a trajetória (entre dois pontos dados) de menor tempo de um corpo, que parte do repouso, restrito a se mover numa superfície esférica e sujeito a um campo gravitacional constante. Através da equação de Euler-Lagrange, obtém-se uma expressão para o tempo total de percurso. O problema foi resolvido numericamente usando técnicas de física computacional e foram obtidos valores numéricos para alguns casos particulares usando o software Mathematica, os quais foram comparados com o tempo de queda livre e com o tempo que o corpo levaria caso se deslocasse pela geodésica da esfera (que liga os dois pontos dados). Além disso, foi estudada a dependência do tempo que o corpo leva para chegar ao final da trajetória com a posição na qual ele é solto numa mesma curva de tempo mínimo (análogo ao problema da tautócrona no plano).
Role of low dose 256-slice CT perfusion imaging in predicting mediastinal lymph node metastasis of lung cancer
Authors: Yang Li , Sun Lu , Liu Jian , Liu Qiang
Published: July 2019

SUMMARY OBJECTIVE: CT perfusion (CTP) is an imaging technique that can be used to evaluate the changes in the microcirculation of tumor tissues. Our study aimed to investigate the role of CTP in predicting mediastinal lymph node metastasis. METHODS: Clinical data of 58 patients who received surgical resection of lung cancer and lymph node dissection in our hospital from June 2012 to December 2014 were collected. Patients were divided into a positive lymph node metastasis group and a negative lymph node metastasis group. Parameters of CTP, including peak enhancement intensity (PEI), perfusion value (PV), as well as blood volume (BV), were compared between the two groups. The receiver-operating characteristic (ROC) curve was used to predict mediastinal lymph node metastasis. RESULTS: The PV of the positive lymph node metastasis group was significantly higher than that of the negative group (p < 0.001). The ROC curve analysis showed that PV can be used as an index to predict mediastinal lymph node metastasis of lung cancer. The sensitivity and specificity of a PV greater than 7.5ml·min-1·ml-1 in predicting lymph node metastasis of lung cancer were 78.3 % and 91.4 %, respectively. CONCLUSION: The PV of low dose CT perfusion can be used as an index for predicting mediastinal lymph node metastasis of lung cancer.
Primary Neural Leprosy mimicking rheumatological disorders
Authors: Freitas Renata Carolina Schlögel de , Pereira Carlos Augusto Zanardini , Muri Nadia Tannous , Franzon Valéria Aparecida Zanela , Fatuch Carlos Alberto Camorim
Published: July 2019

SUMMARY Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which affects mainly the skin and peripherical nerves. Brasil has not yet achieved its goal of elimination of the number of cases of this disease, ranking second in terms of absolute numbers worldwide, with India occupying the first position. Primary Neural Leprosy is considered to be a challenge in diagnosis, since it affects the peripherical nerve system with the absence of skin lesions, thus mimicking rheumatological disorders, like in the case presented. A male, 31, with no previous comorbidities, five years ago, started feeling severe pain in the left ankle as well as morning hand pain and stiffness. After many years of being submitted to intense rheumatological disease investigation, they all proved to be negative. Upon physical examination, the patient presented no skin lesions, symmetric polyarthritis in metacarpophalangeal joints and thickness of the left sural nerve. Lab exams showed no alterations and bacilloscopy was negative. Ultrasonography was used to investigate the thickness of the left sural nerve. Biopsy showed a minimal amount of perineural lymphocytes and positive AFB testing. Based on the electroneuromyography, the conclusion was multiple mononeuropathy, and multibacillary polychemotherapy was started. Leprosy remains a public health problem in Brasil. Due to the high prevalence of the disease, our medical colleagues must be alert and trained to recognize this clinical presentation of leprosy. Correct referral to Reference Centers accelerates research, contributing to an accurate diagnosis, classification, and treatment, thus preventing irreversible sequelae with severe functional disability.
Efficacy and safety of percutaneous transforaminal endoscopic discectomy in the treatment of lumbar spinal stenosis combined with osteoporosis
Authors: Gu Xiaobin , Zhu Wenhui , He Haiyi , Wang Zili , Ding Shaolong , Guo Gaosheng
Published: July 2019

SUMMARY OBJECTIVE: To investigate the efficacy and safety of percutaneous transforaminal endoscopic discectomy (PTED) in the treatment of lumbar spinal stenosis (LSS) combined with osteoporosis. METHODS: Eighty patients with LSS combined with osteoporosis were divided into a control and PTED group, which received conventional transforaminal lumbar interbody fusion and PTED, respectively. The surgical indications, incision visual analogue scale (VAS), lumbar and leg pain VAS, lumbar Japanese Orthopaedic Association (JOA) and Oswestry disability index (ODI) scores, bone mineral density (BMD), and adverse reactions were observed. RESULTS: Compared with the control group, in the PTED group, the operation time, bleeding loss and hospitalization duration, incision VAS scores at postoperative 12, 24 and 48 h and lumbar and leg pain VAS and lumbar ODI scores on postoperative 6 months were significantly decreased (P < 0.01), and the lumbar JOA score on postoperative 6 months was significantly increased (P < 0.05). There was no significant difference in BMD between two groups (P > 0.05). Compared with the control group, in the PTED group, the total effective rate was significantly higher (P < 0.05), and the incidence of adverse reactions was significantly lower (P < 0.05). CONCLUSIONS: PTED is safe and effective in the treatment of LSS combined with osteoporosis.
The study of copy number variations in the regions of PRKAB2 and PPM1K among congenital heart defects patients
Authors: Dong Han-Quan , Du Yue-Xin
Published: July 2019

SUMMARY OBJECTIVE: This study was to assess the genetic association of copy number variations in two genes (PRKAB2 and PPM1K) located in two regions (tetralogy of Fallot and ventricular septal defect) in a Chinese Han population. METHODS: A total of 200 congenital heart disease patients (100 tetralogy of Fallot patients and 100 ventricular septal defect patients) and 100 congenital heart defect-free controls were recruited, and quantitative real-time PCR analysis was used to replicate the association of two copy number variations with congenital heart defects in a Chinese Han population. RESULTS: One deletion at PRKAB2 and one duplication at PPM1K were found in two of the tetralogy of Fallot patients, respectively; while all these regions were duplicated in both ventricular septal defect patients and in the 100 congenital heart defects-free controls. CONCLUSIONS: We replicated the copy number variations at the disease-candidate genes of PRKAB2 and PPM1K with tetralogy of Fallot in a Chinese Han population, and in patients with ventricular septal defect mutations in these two genes were not found. These results indicate the same molecular population genetics exist in these two genes with different ethnicity. This shows that these two genes are possibly specific pf tetralogy of Fallot candidates.
Time-motion analysis of competitive surfers: Portuguese championship
Authors: Minghelli Beatriz , Paulino Sara , Graça Sara , Sousa Inês , Minghelli Priscilla
Published: July 2019

SUMMARY BACKGROUND: Time-motion analysis has been used to provide detailed insight into surfers’ performance. This study evaluated surfers’ activity times at the Portuguese surfing championship in order to account for the time spent in each surfing activity. METHODS: Eighty-seven individually recorded videos of surfers were analyzed, showing their activity over the entire heat, and video analysis software was used to obtain each surfer's activity profile in the competition. RESULTS: The results breakdown by time percentage show that the surfers were paddling 50.9% of the time, sprint paddling for wave 1.9%, were stationary 34.1% of the time, wave riding 3.7%, and involved in miscellaneous activities (e.g., duck diving, board recovery, etc.) 9.4% of the total time. Average times spent in each surfing activity were 18.6 seconds for paddling, 2.9 seconds for sprint paddling for a wave, 21.7 seconds for the stationary period, 11.5 seconds for wave riding, and 6.9 seconds for miscellaneous activities. CONCLUSIONS: The data revealed that the most performed heat activity was paddling, allowing us to conclude that surfing is basically a long-arm paddling activity and that this activity constitutes a specific surfing competition demand, which in turn means that individual surfer's data can be used as a starting point for the development of tailored conditioning training programs.
Using a 3D printer in cardiac valve surgery: a systematic review
Authors: Boll Liliana Fortini Cavalheiro , Rodrigues Guilherme Oberto , Rodrigues Clarissa Garcia , Bertollo Felipe Luiz , Irigoyen Maria Claudia , Goldmeier Silvia
Published: July 2019

SUMMARY BACKGROUND: The use of the 3D printer in complex cardiac surgery planning. OBJECTIVES: To analyze the use and benefits of 3D printing in heart valve surgery through a systematic review of the literature. METHODS: This systematic review was reported following the Preferred Reporting Items for Systematic Review and registered in the Prospero (International Prospective Register of Systematic Reviews) database under the number CRD42017059034. We used the following databases: PubMed, EMBASE, Scopus, Web of Science and Lilacs. We included articles about the keywords “Heart Valves”, “Heart Valve Prosthesis Implantation”, “Heart Valve Prosthesis”, “Printing, Three-Dimensional”, and related entry terms. Two reviewers independently conducted data extraction and a third reviewer solved disagreements. All tables used for data extraction are available at a separate website. We used the Cochrane Collaboration tool to assess the risk of bias of the studies included. RESULTS: We identified 301 articles and 13 case reports and case series that met the inclusion criteria. Our studies included 34 patients aged from 3 months to 94 years. CONCLUSIONS: Up to the present time, there are no studies including a considerable number of patients. A 3D-printed model produced based on the patient enables the surgeon to plan the surgical procedure and choose the best material, size, format, and thickness to be used. This planning leads to reduced surgery time, exposure, and consequently, lower risk of infection.
Analysis of predisposing factors for chronic subdural hematoma recurrence
Authors: Santos Rafael Gomes dos , Xander Paulo Adolfo Wessel , Rodrigues Leonardo Henrique da Silva , Costa Guilherme Henrique Ferreira da , Veiga José Carlos Esteves , Aguiar Guilherme Brasileiro de
Published: July 2019

SUMMARY OBJECTIVES: To identify recurrence and its potential predisposing factors in a series of 595 patients with an initial diagnosis of Chronic Subdural Hematoma (CSDH) who underwent surgical treatment at a Reference Hospital of São Paulo. METHODS: A retrospective descriptive study, in which the medical records of all patients with a CSDH diagnosis submitted to surgical treatment from 2000 to 2014 were analyzed. RESULTS: The final study population consisted of 500 patients with a diagnosis of CSDH (95 patients with a diagnosis of Cystic Hygroma were excluded), of which 27 patients presented recurrence of the disease (5.4%). There were no statistically significant differences in relapses when cases were stratified by gender, laterality of the first episode or surgical procedure performed in the first episode (trepanning vs. craniotomy). It was possible to demonstrate an age-related protective factor, analyzed as a continuous variable, regarding the recurrence of the CSDH, with a lower rate of recurrence the higher the age. CONCLUSIONS: The results indicate that, among possible factors associated with recurrence, only age presented a protective factor with statistical significance. The fact that no significant difference between the patients submitted to trepanning or craniotomy was found favors the preferential use of burr-hole surgery as a procedure of choice due to its fast and less complex execution.
Reactional changes in short-term levonorgestrel-releasing intrauterine system (lng-ius) use
Authors: Giraldo Paulo César , Souza Thais Coelho de , Henrique Guilherme Lindman , Monteiro Ilza , Amaral Rose , Machado Rogério Bonassi , Discacciati Michelle Garcia , Sanches José Marcos
Published: July 2019

SUMMARY OBJECTIVE: To evaluate endocervical and vaginal environment changes in women using a levonorgestrel-releasing intrauterine system (LNG-IUS). METHODS: A quasi-experimental study included sixty women who had an LNG-IUS inserted in the Family Planning Clinic of UNICAMP between April and November of 2016. Women in reproductive age, non-pregnant, without the use of antibiotics and contraceptives seeking for LNG-IUS insertion were selected for this study. All women were evaluated with regard to vaginal and endocervical pH, vaginal and endocervical Gram-stained bacterioscopy, and Pap-smear before and two months after LNG-IUS insertion. Clinical aspects such as cervical mucus, vaginal discharge, and cervical ectopy were also observed. RESULTS: After LNG-IUS insertion, there was an increase in the following parameters: endocervical pH>4.5 (p=0.02), endocervical neutrophil amount (p<0.0001), vaginal cytolysis (p=0.04). There was a decrease in vaginal discharge (p=0.01). No statistically significant changes were found in vaginal pH, neutrophils amount in the vaginal mucosa, vaginal discharge appearance, vaginal candidiasis, bacterial vaginosis, vaginal coccobacillary microbiota, cervical mucus appearance, or cervical ectopy size. CONCLUSIONS: Short-term LNG-IUS use did not increase vulvovaginal candidiasis or bacterial vaginosis, and led to diminished vaginal discharge. Notwithstanding, this device promoted reactional changes in the vaginal and endocervical environment, without modification on cervical ectopy size.
Clinical research on lumbar oblique-pulling manipulation in combination with sling exercise therapy for patients with chronic nonspecific low back pain
Authors: Wang Shang-Quan , Chen Ming , Wei Xu , Gao Xin-Xia , Zhao Guo-Dong
Published: July 2019

SUMMARY OBJECTIVE: To investigate clinical curative effects of lumbar oblique-pulling manipulation in combination with sling-exercise-therapy training on chronic nonspecific lower back pain. METHODS: A total of 60 patients with chronic nonspecific lower back pain in the Outpatient Department were included in this study. These patients were randomly divided into two groups: the observation group and the control group. The control group adopted a single sling-exercise-therapy training three times a week, while the observation group adopted lumbar oblique-pulling manipulation in combination with manipulation treatment once a week. The course of treatment lasted for four weeks. RESULTS: (1) Before and after treatment, the ODI score was compared within the group. A remarkable statistical significance was observed from the third day (P<0.05). At the third month of follow-up, the difference in ODI scores between these two groups was statistically significant (P<0.05). (2) Before and after treatment, it was observed that differences in VAS scores from the third day were statistically significant (P<0.05). (3) The difference in muscle strength between these two groups had remarkable statistical significance in the third month of follow-up (P<0.05). CONCLUSION: The effective rehabilitation function of lumbar oblique-pulling manipulation in combination with sling-exercise-therapy training in patients with CNLBP is superior to that of sling-exercise-therapy training alone.
The role of Survivin as a biomarker and potential prognostic factor for breast cancer
Authors: Veiga Glaucia Luciano da , Silva Raissa Daniel Machado da , Pereira Edimar Cristiano , Azzalis Ligia Ajaime , Alves Beatriz da Costa Aguiar , Gehrke Flavia de Sousa , Gascón Thaís Moura , Fonseca Fernando Luiz Affonso
Published: July 2019

SUMMARY Breast cancer (BC) is one of the primary health problems worldwide. As the most common cancer in women in the world and in Brasil, behind only non-melanoma skin cancer, this neoplasm corresponds to approximately 28% of new cases per year in the country. BC also affects men, although the incidence corresponds to only 1% of total cases. Currently, most of the chemotherapeutic agents used in BC treatment are extremely toxic and cause long-term side effects. There is also a need to obtain earlier diagnoses, more accurate prognoses and make new therapies available that are more selective and effective in order to improve the current scenario. Therefore, this work sought to evaluate the importance of the biomarker survivin (Sur) in relation to BC, through the detailing of the role of Sur as a biomarker, the correlation between this protein and the prognosis of BC patients, and a summary of therapeutic strategies that target Sur for the development of new anticancer therapies.
Pathological fracture after radiotherapy: systematic review of literature
Authors: Soares Cláudio Beling Gonçalves , Araújo Ivana Duval de , Pádua Bruno Jannotti , Vilela José Carlos Souza , Souza Rodrigo Henriques Reis , Teixeira Luiz Eduardo Moreira
Published: July 2019

SUMMARY OBJECTIVE: To evaluate the epidemiological data and available treatments for fractures secondary to radiotherapy treatment. METHODS: Identification of publications on pathological skeletal fractures previously exposed to ionizing radiation. RESULTS: The incidence of fractures after irradiation varies from 1.2% to 25% with a consolidation rate of 33% to 75%, being more frequent in the ribs, pelvis, and femur. The time elapsed between irradiation and fracture occurs years after radiotherapy. Risk factors include age above 50 years, female gender, extensive periosteal detachment, circumferential irradiation, tumor size, and anterior thigh location. The etiology is still uncertain, but cellular disappearance, reduction of bone turnover and activity were observed hematopoietic as possible causes of failure of consolidation. CONCLUSION: There is no consensus in the literature on the factors related to the development of fractures, with radiation dose, previous tumor size and periosteal detachment being suggested as potential factors.
Fulminant acute hepatitis in pediatrics in Latin America and the Caribbean
Authors: Colleti Junior José , Caino Felipe Rezende , Teixeira Rafael , Carvalho Werther Brunow de
Published: July 2019

SUMMARY OBJECTIVE: The objective of this review was to investigate the epidemiology of Fulminant Acute Hepatitis in Latin America and the Caribbean and identify possible measures aimed at a better understanding and improvement of patient support. METHODS: We used 3 different researchers to investigate the topic of Fulminant Acute Hepatitis in pediatrics in papers published by Latin American and Caribbean authors in the PubMed and SciELO databases from 2000 to 2016. RESULTS: We found 2,879 articles in the databases searched. After selecting and excluding articles according to the study protocol, 68 remaining studies were obtained for analysis. A total of 1,265 cases of acute fulminant hepatitis were detected, with a predominance of females (42.9%), followed by males (39.4%), with no description of sex in 17.7% of the cases. The main cause was viral hepatitis, representing 45.1% of the cases. The hepatitis A virus was responsible for 34.7% of the total cases and 76.9% of the infectious causes. Of the total number of patients, 26.9% were described as idiopathic, and 11.5% had no cause. CONCLUSION: The preventable causes of Fulminant Acute Hepatitis include hepatitis viruses - primarily the hepatitis A virus - and poisoning. Active vaccination, basic sanitation, and public awareness can reduce the number of patients and, consequently, the costs of liver transplantation due to these causes.
Association between the Diet Quality Index Adapted for Pregnant Women (IQDAG) and excess maternal body weight
Authors: Crivellenti Lívia Castro , Zuccolotto Daniela Cristina Candelas , Sartorelli Daniela Saes
Published: July 2019

Abstract Objectives: to investigate the relationship between the Diet Quality Index Adapted for Pregnant Women (IQDAG) and excess maternal body weight. Methods: a cross-sectional study was conducted with 754 adult pregnant women, in Ribeirão Preto, São Paulo, between 2011 and 2012. The criteria proposed by Atalah were used to classify the body mass index (BMI). Adjusted multinomial logistic regression models were employed to investigate the relationship between the IQDAG and being overweight and obese, estimating the odds ratio (OR) and the 95% confidence interval (CI95%). Results: the mean (SD) age of women was 28 (5) years, 33.4% were overweight and 25.6% obese. The pregnant women with higher scores in the IQDAG were less likely to be overweight [OR= 0.56 (CI95% = 0.37-0.85)] or obese [0.43 (0.26-0.71)]; those with higher scores in the "Fiber" [0.51 (0.33; 0.78)] and "Iron" [0.62 (0.40-0.96)] components were less likely to be overweight. However, women with higher scores in the percentage of energy from ultra-processed foods were more likely to be overweight [1.72 (1.10-2.94)] or obese [5.24 (2.80-9.80)], when compared to women with lower scores. Conclusions: poorer quality maternal diets were observed among the women who were overweight and obese during pregnancy.
Ecuadorian infant mortality linked to socioeconomic factors during the last 30 years
Authors: Romero-Sandoval Natalia , Alcázar Diego Del , Pastor Jacob , Martín Miguel
Published: July 2019

Abstract Objectives: to analyze the difference among geographical units and the evolution of infant mortality rate (IMR) based on Ecuadorian censuses (1990-2001-2010). Methods: artificial Neural Network analyzed the impact of sociodemographic factors over the variability of IMR. Poisson regression analyzed the variation of the standardized IMR (sIMR). Results: the decrease in the national IMR was 63.8%; however, 42.8% provinces showed an increase in 2001-2010. The variability was explained mainly by illiteracy decrease. The adjusted RR between provincial sIMR with illiteracy and poverty revealed a trend towards the unit. Conclusions: the variation of IMR reflects a complex interaction of the sociodemographic factors.
Prevalence and determinants of the use of pacifiers and feedingbottle: a study in Southwest Bahia
Authors: Bezerra Vanessa Moraes , Magalhães Elma Izze da Silva , Pereira Itana Neves , Gomes Andressa Tavares , Pereira Netto Michele , Rocha Daniela da Silva
Published: July 2019

Abstract Objectives: to assess the use of pacifier and feedingbottle and their determinants in children from a municipality of Southwest Bahia. Methods: a cross-sectional study was performed with 354 children younger than 12 months old. The event was categorized in: exclusive use of pacifier, exclusive use of feeding bottle,use of pacifier and feeding bottle, and not use any of them. Multinomial analysis with logistic regression was applied, and those who did not use any artificial nipples were thereference variable. Results: it was observed that 11.9% of the children exclusively used pacifiers, 21.2% only use bottles and 32.8% used both of them. The following factors were associated with the exclusive use of pacifiers: low maternal schooling level (eight or less years of education), lack of previous experience with breastfeeding, difficulty in postpartum breastfeeding, and lack of incentive to breastfeeding in puericulture. The exclusive use of feeding bottle was associated with unmarried mothers, aged 35 years old or older, and with less years of education (eight or less years). Women who worked outside home and had difficulty in breastfeeding had greater chance of giving both artificial nipples to the children. Conclusions: the findingspresent different featuresrelated to the exclusive or combined use of pacifiers and feeding bottles, being important to direct health professionals conducts towards mothers’ orientation.