bluuebunny/crossref_metadata_2025 huggingface dataset:
Behavioural phenotyping of C. elegans on UV-killedE. colimutants v1
Authors: Moore Saul
Published: November 2021

Protocol for screening candidate behaviour-modifying E. coli BW25113 single-gene deletion mutants from the 'Keio Collection', to investigate their effects on Caenorhabditis elegans behaviour when killed by ultraviolet (UV) light
[RETRACTED] Guardian Blood Balance Australia - Does Botanicals Blood BalanceAustralia Really Work? Is it Safe to Use? Read Reviews, Price, Where to Buy in Australia & Canada. v1
Authors: not provided pharmaflexrxreviews
Published: November 2021

[RETRACTED]

Health
Growing overnight bacterial culture in 96WP (Cabreiro Lab) v1
Authors: Moore Saul
Published: November 2021

Luria broth (LB) is a nutrient-rich media commonly used to culture bacteria in the lab. LB agar plates are frequently used to isolate individual (clonal) colonies of bacteria carrying a specific plasmid. However, a liquid culture is capable of supporting a higher density of bacteria and is used to grow up sufficient numbers of bacteria necessary to isolate enough plasmid DNA for experimental use. The following protocol is for inoculating an overnight culture of liquid LB with bacteria. This is a general protocol for making a liquid bacterial culture in 96-well plate format from frozen stock plates. The following parameters need to be mentioned for the specific type of bacterial strains inoculated: Parameters Example 1. Name/s of the bacterial strain OP50 2. Growth temperature 37C 3. Incubation time 16-18hrs 4. Antibiotic resistance (if any) None 5. Rpm of the shaking incubator (if needed) 200-220 rpm if required
Making normal NGM for imaging plates (Cabreiro Lab) v1
Authors: Moore Saul
Published: November 2021

C. elegans is maintained in the laboratory on Nematode Growth Medium (NGM) agar which has been aseptically poured into petri plates. The NGM agar medium can be poured into petri plates easily and aseptically using a peristaltic pump. This pump can be adjusted so that a constant amount of NGM agar is dispensed into each petri plate. A constant amount of agar in the plates reduces the need for refocusing the microscope when you switch from one plate to another. The imaging plates can be 35mm, 60mm or 90mm in diameter depending on the assay design.
Egg Prep forBleach Synchronization (Cabreiro Lab) v1
Authors: Moore Saul
Published: November 2021

Egg prep protocol for bleach synchronisation of C. elegans.
Tissue extraction from whole caterpillars v1
Authors: JN Kitson James
Published: November 2021

This protocol is designed for extracting DNA from Lepidopteran larvae but it will work on most animal tissue with some modifications to tube volumes and homogenisation settings.
Catalytic Hydrogenation of Furfural Diethyl Acetal to Ethyl Furfuryl Ether
Authors:   Institute of Chemistry and Chemical Technology SB RAS, Tarabanko Valery E. , Simakova Irina L. ,   FRС Boreskov Institute of Catalysis SB RAS, Smirnova Marina A. , Kaygorodov Konstantin L.
Published: November 2021

The process of catalytic hydrogenation of furfural diethyl acetal to ethyl furfuryl ether on the different catalysts (palladium, palladium-rhenium and copper-ruthenium on Sibunit in reduced forms) was studied. It was found that hydrogenation of the furan ring with the formation of THF diethyl acetal occurs on all the catalysts. Ethyl furfuryl ether becomes the main product while carrying on the second hydrogenation cycle on spent palladium catalyst (yield and selectivity up to 55 % and 85 %, respectively)
Adsorption-Luminescent Determination of Y(III) Using 8-oxyquinoline Derivatives Fixed on the Silica Surface
Authors:   Siberian Federal University, Buyko Olga V. , Losev Vladimir N. , Shimanskii Alexander F.
Published: November 2021

Silicas, sequentially modified with polyhexamethylene guanidine and 8-hydroxyquinoline‑5-sulfonic acid (SiO2-PHMG‑oxine) or 7-iodine‑8-hydroxyquinoline‑5-sulfonic acid (SiO2-PHMG‑ferron), have been proposed for the adsorption-luminescent determination of Y(III) in natural waters. Complex compounds of Y(III) are formed on the surface of adsorbents during adsorption from solutions at pH 6–7, which luminesce in a yellow-green color (λlum = 485 nm (SiO2-PHMG‑oxine) and λlum = 490 nm (SiO2-PHMG‑ferron)). This is the basis for the method of its sorption-luminescent determination. The detection limit of Y(III), calculated according to the 3s criterion, is 1 μg/L (SiO2-PHMG‑oxine) and 2 μg/L (SiO2-PHMG‑ferron), the analytical range is 4–400 μg/L (SiO2-PHMG‑oxine) and 6–500 μg/L (SiO2-PHMG‑ferron). The developed methods were tested in the determination of yttrium in the Yenisei and Kacha rivers of the Krasnoyarsk Krai
Specific of Stable Carbon Isotopes Determination in Organic-Bearing Sediments
Authors:   V.S. Sobolev Geology and Mineralogy SB RAS, Lazareva Elena V.
Published: November 2021

The study of the carbon isotopic composition in organic-bearing bottom sediments of the thermal lake Fumarolnoye (Uzon caldera, Kamchatka) has been carried out. The results of studying δ13C changes in the bottom sediments of a thermal lake during the sequential extraction of H3PO4 for 2 hours, 24 hours and 7 days are presented. The change in δ13С with time and after treatment with HCl and H2O2 is shown using two samples as an example. After treatment with HCl, the δ13С values change relative to the initial ones from 1 to 3 ‰, which can be taken into account when interpreting the data. The standard procedure for removing carbonate with hydrogen peroxide reveals a significant transformation of the residual C‑containing substance in the case of a prolonged reaction with H3PO4 at elevated temperatures
Uni-pluriversidad: 20 años de evolución del concepto de Universidad
Authors: Toledo Lara Gustavo Eduardo
Published: November 2021

Se presenta una revisión sobre la evolución de la definición de Universidad a lo largo de 20 años de la revista Uni-pluriversidad. Para esto, se establecieron dos fases: 1) aproximación teórica sobre el concepto y tipos de Universidad y 2) revisión de un conjunto de artículos para identificar las tendencias que han acompañado la definición de Universidad expuestas por los investigadores. Desde una perspectiva analítica-interpretativa y asumiendo la teoría fundamentada, se revisaron 590 artículos y se seleccionaron 41 para el muestreo comparativo constante y el muestreo teórico, identificando elementos similares o diferentes. Se concluye que una sola definición de Universidad no existe, aunque, desde el año 2001, se han expuesto en la revista elementos definitorios que pueden caracterizar la Universidad a la luz del contexto y de su pertinencia social, sin dejar de lado sus funciones tradicionales dentro del espectro de instituciones dedicadas a la formación universitaria.
Dental health of civil aviation flight personnel
Authors: Iordanishvili Andrey K.
Published: November 2021

BACKGROUND: Preservation and strengthening of the health of civil aviation flight personnel is an extremely urgent problem and is associated with ensuring flight safety.
AIM: This study aimed to determine the structure and analyze the organs and tissues of the masticatory apparatus among civil aviation flight personnel.
MATERIALS AND METHODS: To determine the incidence and intensity of main dental diseases and the morbidity structure of organs and tissues of the masticatory apparatus in civil aviation pilots, an in-depth examination was carried out in 120 men aged 2545 years (study group 1) working on various modern passenger and transport aircrafts. The duration of flight operations ranged from 2 to 17 years, with a total flight duration of 140 to 5580 h. The comparison group consisted of 146 men (aged 2545 years) of non-flying specialties (study group 2). The generally accepted methods for assessing the prevalence and intensity of the course of major dental diseases were used.
RESULTS: The incidence and intensity of dental disorders, periodontal disease, temporomandibular joint disorders, and parafunctions of the masticatory muscles were defined. The incidence and intensity of major dental diseases among civil aviation flight personnel were clearly directly proportional to their flight time (r=0.547) and duration of work in civil aviation (r=0.482) but to a lesser extent to their age (r=0.416).
CONCLUSIONS: Non-carious lesions of the teeth, inflammatory and dystrophic diseases of the periodontal and oral mucosa, painful dysfunction of the temporomandibular joint, and bruxism are more common among civil aviation flight personnel than among non-flying personnel, which is due to the unfavorable effect of air flight factors on organs and tissues of the mastication apparatus and the body of the pilots as a whole.
Expression of saliva biomarkers in patients with squamous cell carcinoma in various regions of the oral mucosa
Authors: Kochurova Ekaterina V. , Nikolenko Vladimir N. , Panferova Olga I. , Izhnina Ekaterina V. , Kudasova Ekaterina O. , Yumashev Alexey V. , Mikhailova Maria V.
Published: November 2021

BACKGROUND: Oral fluid as a means for early detection and differential diagnosis of diseases of the oral mucosa and for assessing the overall somatic status of the body attracts the attention of researchers due to the non-invasiveness of material sampling and the exclusion of risks possible during blood analysis, as well as a simpler, compared with blood samples, material storage regime.
AIM: The study aimed to evaluate the levels of oral fluid biomarkers of 170 patients with squamous cell carcinoma of the oral mucosa (RCC-MOP) depending on the localization of the oncopathology.
MATERIALS AND METHODS: This study analyzed the levels of oral fluid biomarkers of 170 patients with RCC-MOP depending on the localization of oncopathology. Matrix metalloproteinases (MMPs) 2, 8, and 9, as well as their tissue inhibitors (TIMPs) 1 and 2, were chosen as biomarkers. For a comparative analysis, lesions of the tongue, cheek, floor of the oral cavity, alveolar ridge of the jaw, and oropharynx were selected.
RESULTS: The study showed significant differences in the biomarker levels in the localization of squamous cell carcinoma in different parts of the oral mucosa.
CONCLUSIONS: Analysis of the expression of oral fluid biomarkers with RCC-MOP revealed a link between the localization of the oncopathology and the level of synthesized biomarkers. The peak values of MMPs in the lesions of the tongue and floor of the oral cavity may be associated with the high number of salivary glands in these anatomical areas. The expression level is influenced by a number of factors, such as the localization of the pathological process, dental status, age, gender, and general condition of the patient.
Clinical efficiency of ultraphonophoresis of Metrogyl Denta gel in mild periodontitis
Authors: Volkov Alexander G. , Morozov Dmitry I. , Dikopova Nataliya Zh. , Olesov Egor E. , Sinyakov Alexandr I.
Published: November 2021

BACKGROUND: Periodontal diseases are one of the most common in dentistry. Along with the complications of caries, periodontitis is one of the causes of tooth loss. In the etiology of this disease, the leading role is played by the microbial factor, as well as microcirculatory disorders in periodontal tissues. The complex mechanism of periodontitis development involves a comprehensive treatment approach aimed at different links in the pathogenesis of the development of this disease. Among the numerous physical factors used in the treatment of periodontal diseases, ultraphonophoresis, which combines the effects of ultrasound and a medicinal substance, is not widely used. The study of the effectiveness of the use of Metrogil Denta gel ultraphonophoresis in the treatment of inflammatory periodontal diseases is of considerable scientific and practical interest.
AIM: This study aimed to investigate the effect of ultraphonophoresis of gel on the clinical course of chronic generalized periodontitis of moderate severity.
MATERIALS AND METHODS: Sixty patients (aged 3162) with chronic generalized periodontitis of moderate severity were examined and treated. In the main group (n=30), treatment included high-frequency ultrasound and antibacterial preparation of Metrogyl Denta gel applied to the periodontal tissue (ultraphonophoresis of Metrogyl Denta gel). In the control group (n=30 patients), Metrogyl Denta gel was injected into the periodontal tissue.
RESULTS: Application of Metrogyl Denta gel for moderate periodontitis did not improve local blood circulation. Six months after treatment, nearly half of the examined patients showed signs of inflammation, which was accompanied by a worsening of periodontal index (PI), SchillerPisarev tests results, and rheography finding. Twelve months after treatment, 63% of the patients developed complications.
CONCLUSIONS: There was further deterioration in the clinical and functional parameters. After ultraphonophoresis of Metrogyl Denta gel, there was a decrease in the readings of the SchillerPisarev test, PI, and normalization of the qualitative and quantitative indicators of the rheoparodontogram, which indicated a decrease in inflammation and activation of local blood circulation in the periodontium. In the long term after treatment, despite the increase in hygiene index, the relative stability of clinical and functional parameters was maintained. Even a year after treatment, the level of indicators did not reach the level obtained before treatment.
Determination of the minimum suppressing concentration to metronidazole in representatives of obligate and optional anaerobic microflora of periodontal pockets
Authors: Olesov Egor E. , Morozov Dmitry I. , Volkov Alexander G. , Dikopova Nataliya Zh. , Ponomareva Anna G.
Published: November 2021

BACKGROUND: Due to the long period of use of metronidazole in medical dental practice, today it is relevant to study the sensitivity and the minimum inhibitory concentration of reference and clinical strains of obligate anaerobic microbiota to metronidazole in periodontitis.
AIM: Determination of sensitivity and minimum suppressive concentration of reference and clinical strains of obligate anaerobic microbiota to metronidazole in periodontitis.
MATERIALS AND METHODS: Strains of obligate anaerobic microbiota of periodontal pockets with moderate periodonitis were isolated from 30 patients. The study was carried out by the cassette micromethod, which is a modification of the method for determining the sensitivity by serial dilution in a dense agar medium.
RESULTS: As a result of the study, it was found that many of the microbes found in periodontal pockets have a relatively low sensitivity to metronidazole (MIC from 4 to 12 g / ml). This circumstance is obviously due to the fact that this antibacterial chemotherapy drug has been used for a long time in periodontal practice.
CONCLUSIONS: In this regard, in order to increase the effectiveness of local antibacterial therapy, this chemotherapy drug must be combined with antiseptics that have a pronounced antibacterial effect against periodontal pathogenic microflora, for example, Metrogyl Dent gel, containing, along with metronidazole, the antiseptic chlorhexidine, as well as the use of physical hardware methods of exposure to create significant the concentration of the antibacterial drug in the mucous membrane and in the contents of periodontal pockets, which can be done using phonophoresis.
Evaluation of the influence of sports loads on the maxillofacial area of cheerleaders
Authors: Sevbitov Andrey V. , Zyulkina Larisa A. , Teplova Anna V. , Dorofeev Alexey E. , Yershov Kilill A. , Sevbitov Alexander A.
Published: November 2021

BACKGROUND: At the moment, it has not been sufficiently studied what effect physical exercises with weights have on the condition of the hard tissues of the teeth, periodontal and temporomandibular joint.
AIM: Study the effect of serious sports loads on individual organs and tissues of the human body, including dental health.
MATERIALS AND METHODS: A clinical examination and questionnaire survey of 60 cheerleader athletes were conducted. The criteria for inclusion in the study were the age from 15 to 27 years, constant cheerleading training for more than 6 months, and the presence of voluntary informed consent. Exclusion criteria: age less than 15 years and older than 27 years, constant cheerleading training for less than 6 months, refusal to participate in the survey. The patients were divided into two equal groups: Group 1 college cheerleader athletes; Group 2 university cheerleader athletes. The groups were divided into three subgroups: 1st subgroup engaged in cheerleading from 6 months to 1 year; 2nd subgroup from 1 year to 2 years; 3rd subgroup more than 2 years. When filling out the questionnaire, patients were asked the question: Do you use any means for the prevention and prevention of pathological diseases of the oral cavity?. During the examination of the oral cavity, the degree of tooth abrasion, tongue damage and pathological changes in the temporomandibular joint were assessed.
RESULTS: The results show that the preventive dental activity of patients was low. Most of the respondents had no basic ideas about the prevention of pathological changes in the oral cavity during cheerleading.
CONCLUSIONS: The results of the study show that the preventive dental activity of the participants was low. Thus, there is a need to develop tools and materials for the effective prevention of tooth abrasion, tongue damage, and pathological changes in the temporomandibular joint.
Application of ultrasound in the complex treatment of periodontitiss
Authors: Paramonova Irina A. , Volkov Alexander G. , Dikopova Nataliya Zh. , Paramonov Yuriy O. , Akhmedbaeva Sevara S.
Published: November 2021

Ultrasound refers to physical factors that can have a multi-sided therapeutic effect in periodontitis. In therapeutic doses, it affects a variety of local tissue reactions, stimulates compensatory, restorative, protective and adaptive mechanisms. For ultrasound therapy modern industry offers two types of devices that are able to generate ultrasonic vibrations in a wide frequency range: low frequency (2040 kHz) and high frequency (more than 800 kHz).The comparative study of the use of low-frequency and high-frequency ultrasound therapy in the complex of therapeutic measures for periodontitis is now of great scientific and practical interest.
Isulin-cortisol shifts in timely-temporal structure of functions in postmenopause
Authors: Zazerskaya I. E. , Ailamazyan A. K. , Kornilov N. V. , Avrunin A. S. , Sukhanova A. M.
Published: November 2021

We screened serume levels of insulin and cortisol in 20 postmenopausal women. We performed these hormones determinations according to algorithm of their levels circaseptane oscillation. All examined patients did't complain on climacteric disorders and did't have any endocrinological diseases. We found out 5 types of hormone oscillations: when the concentrations of both hormones were at normal levels (5% cases); when insulin levels decreased from time to time (30% cases); when cortisol levels increased from time to time (35% cases); when during insulin levels' decreasing the cortisol levels has increased (25% cases); when both hormones levels increased from time to time.
The prenatal diagnostics in optimization of pregnancy outcome
Authors: Savelieva G. M. , Sichinava L. G. , Panina O. B. , Gnetetskaya V. A.
Published: November 2021

In order to improve the quality of prenatal diagnostics we have evaluated and optimised the indications to the complex investigation of revealing fetal abnormalities and chromosomal diseases. Taking into account a couple of extra-factors we succeeded to prevent the birth of abnormal children in 10% cases. To assess the possibility of pregnancy complications prognosis we have ultrasonographically studied the features of extraembryonal structures development in 1st trimester pregnancy. We have observed the high prognostic value of chorionic and amniotic cavities volumes and yolk sac pathology in predicting the preterm delivery and IUGR.
Bladder-vagina fistulas management
Authors: Semenyuk A. A. , Baskakov V. P. , Chystyakov V. P. , Bytukov N. N. , Meleshko V. V.
Published: November 2021

The difficulty of the problem of fistulas genital treatment is covered in the article given. Though there are certain success, the recurrent fistulas are frequent complication after treatment. There are more than 150 ways of fistulas reconstruction. The results, analysis of 29 surgery procedures in genital fistulas treatment are considered. Authors suggest their original operative method using transvaginal approach, monocry I and PDS use, postoperative bladder drainage consisting of 2 urethral tubes, preventing a spike in bladder pressure. They report about 7 successful results on fistula closure using original technique.
The factors of risk for endomyometritis development after labor
Authors: Kupert A. F. , Solodun P. V. , Kravchuk L. A. , Kupert M. A.
Published: November 2021

The risk factors for endometritis development after labor was studied. Different factors of risk in research and in comparative groups was present in number on the base scale of a prognosis purulent-septic disease in pregnant and parturiens for comparison of their significance. It is confirmed that the significance of preventive measures, that carry out during pregnancy, results in lowering of the endometritis after labor. Endometritis after labor is determined to develop more frequently in women of early reproductive age. The leading significance of the risk factors connected with delivery was confirmed. The leading role in pregnancy belongs to the focus infection both in the extragenital organs and in lower section genital tract. More the threat interrupting in different periods of pregnancy and combination of two and more extragenital diseases in one woman are of significance risk factors.
Bacterial vaginosis and its influence on complications after abortions
Authors: Ivanova L. V. , Stivel L. A. , Popov A. M. , Nemet N. N.
Published: November 2021

In the review, the modern data on etiology, pathogenesis, clinics, diagnostics and treatment of bacterial vaginosis are presented. The probability of abortion complications with ВV existence is considered.
Analysis of loss of professional employment and ability to perform labor activities in sufficiated
Authors: Barkovskaya Olga S. , Gudimov Vitaly B.
Published: November 2021

BACKGROUND: In medical and social expertise, to determine the degree of loss of professional working capacity and disability to victims of industrial accidents and occupational diseases, it is of fundamental importance to assess the possibility of continuing professional activity and the ability to work.
AIMS: To study the structure and dynamics of determining the degree of loss of professional ability to work, the dynamics of disability and the structure of disability groups, the structure of nosological forms among the victims.
MATERIALS AND METODS: The results of the medical and social examination in the FGI The Main Bureau of Medical and Social Expertise in the Novosibirsk region for the period 20132020 have been studied among 1528 victims of industrial accidents and occupational diseases. Of these, the loss of professional ability to work of varying degrees was established by 96.6% of the victims, disability with limited ability to work ― 36.2% of the victims.
RESULTS: The largest share (62.5%) was made up of victims with a loss of professional working capacity from 10 to 30 percent. Among the victims with disabilities, the largest proportion (75.2%) were disabled persons of the third group with limited ability to perform labor activities of the 1st degree. The dynamics of establishing the degree of loss of professional ability to work and disability with limited ability to perform labor activity in the study period was characterized by an increase to a maximum value in 2014, followed by an intermittent decrease to a minimum value in 2020. production and disability with limited ability to perform work activities, the largest number of persons with the consequences of injuries of the upper limb, the consequences of injuries of the lower limb and the consequences of spinal injuries. Among those injured as a result of occupational diseases, persons with sensorineural hearing loss, vibration disease and lung diseases prevailed. Disability with limited ability to perform work activities among victims of occupational diseases in the overwhelming majority of cases was established in persons with sensorineural hearing loss and lung diseases.
CONCLUSION: The decrease in the ability to perform professional activities and the limitation of the ability to perform work activities were more pronounced among victims of industrial accidents than among those injured as a result of occupational diseases.
The spectrum of vital activity restrictions in disabled people due to thyroid cancer
Authors: Pogosyan Gagik E. , Grechko Andrey V. , Puzin Sergey N. , Shurgaya Marina A. , Memetov Servir S.
Published: November 2021

BACKGROUND: The most common malignant neoplasm of the endocrine system is thyroid cancer. In Russia, as in other countries of the world, the incidence rate is steadily increasing. Thus, it is extremely important to assess the problem of health disorders due to thyroid cancer within the framework of socially significant disability caused by malignant neoplasms in the Russian Federation.
AIMS: To analyze the spectrum of types and degree of disability in people with disabilities due to thyroid cancer.
MATERIAL AND METHODS: The article presents the results of the analysis of the spectrum of the main types of disability in the general contingent of disabled people due to thyroid cancer among the adult population of Moscow (20152019).
RESULTS: The dynamics of disability both in the contingent of first recognized and in the contingent of re-recognized disabled people (VPI and PPI) was characterized by an increase in the number of disabled people and the transformation of the structure of general disability. There is a clear change in the ratio towards an increase in the share of PPI from 55.1% in 2015. up to 68.0% in 2019, while the share of VPI decreased from 44.9% in 2015 to 32.0% in 2019. The predominant gender cohort was women, and the age category was the elderly. The main types of life restrictions were the restriction of the ability to self-serve (98.6% of the VPI and 97.9% of the PPI), to work (94.7% of the VPI and 94.6% of the PPI) and to move (21.3% of the VPI, 21.8% of the PPI). A low proportion of restrictions on the ability to control ones behavior, learning, communication and orientation was revealed (0.31.2%). The first degree of disability prevailed in the contingents of VPI and PPI (p 0.0001). In the contingent of men, the proportion of disabled people with the third degree of disability was higher compared to the contingent of women.
CONCLUSION: Dynamic assessment of the degree of severity of functional disorders and associated life restrictions should be carried out at all stages of medical and social rehabilitation in order to monitor the effectiveness of medical and rehabilitation measures, assess the quality of life and prevent progression (secondary prevention of disability).
Legal and Financial Aspects of Housing Resources Management by Local Governments
Authors: Feret Elżbieta
Published: November 2021

The article attempts to indicate the operational principles of local government units in connection with a public task related to housing resources. The assumption of the analysis was to narrow down the issues to only two aspects: legal and financial. First, issues related to the legal grounds of the so-called housing management at the local government level were discussed, and then, the methods of financing tasks in this field by local government units. It should be emphasized that, despite an attempt to refer to local government units operating at various levels, a special place for the discussion was given to the municipality, for which the legislator has reserved the greatest number of housing management tasks. In connection with the functioning of this local government level, the principles of financing the housing management were discussed, taking into account organizational and legal forms and their relationship with municipal budget funds as well as the possibilities of obtaining extra-budgetary funds.
On the Possibility of Acquisitive Prescription by the State of Real Properties Unlawfully Seized under the Provisions of the 1944 Agrarian Reform Decree
Authors: Fiedorczyk Piotr , Stawarska-Rippel Anna
Published: November 2021

The subject of this paper are those factual states that occurred on the basis of the agrarian reform decree and concerned the unlawful seizure by the State of palace-park complexes. It was only after the collapse of real socialism in 1989 that the owners or their legal successors obtained an annulment of the decision to seize the property. However, this was, and is, only the beginning of the struggle, as the State Treasury or its legal successors are claiming before the common courts the acquisitive prescription of the property being the subject to the recovery claim. The divergence of at least 20 years in jurisprudence as to the date of commencement of the period required for acquisitive prescription (1980–1991) is an undesirable phenomenon, requiring the adoption of a coherent approach of the courts. Consequently, the authors of this text represent the view that the period of validity of both the Agrarian Reform Decree and the subsequent legal acts, with particular emphasis on the period of validity of the Decree of 1945 (Journal of Laws no. 28, item 321) and then Article 9 (16) of the Act of 1958 excluded the course of the acquisitive prescription in favour of the State Treasury of the agricultural and forestry properties unlawfully seized by the State. This period lasted until 31 December 1991, i.e. until the final date when Article 9 (16) was in force.
Wybrane instytucje polskiego prawa prywatnego dla ochrony wierzyciela
Authors: Gawlik Zdzisław
Published: November 2021

The subject of this article is the issue of the intensity of the protection of interests of a person who has entered into the orbit of obligatory relations. Institutions used to secure a claim are described, but doubts arise when the securities overlap and multiply when the debtor is declared bankrupt. Not every business venture is successful. Often, for reasons beyond the entrepreneur’s control, he is unable to pay debts owed to his creditors. The creditors, on the other hand, aware of the risk of entering into a contract, seek security to be established. Therefore, it is worth considering how the security should be treated in the event of the debtor’s insolvency. The study indicates that the creditor’s “own securities”, both personal and material, take precedence over the creditors who receive priority as a result of the debtor’s ineffectiveness under the provisions on the actio Pauliana. The author defends the position according to which the precedence referred to in Article 532 of the Civil Code is not the absolute precedence. The problems discussed in the study are of great interest for many representatives of the doctrine and courts. Moreover, with regard to their content, the Polish Ombudsman formulated questions about their compliance with the Constitution of the Republic of Poland. Poland’s adoption of the market economy model makes these problems typical not only for Poland. A number of arguments were put forward to defend the view on the precedence of the security taken by the creditors over the priority granted by the actio Pauliana. To eliminate doubts as to the reciprocal relationship of priorities to pay the claims, an appropriate proposal for the law as it should stand (de lege ferenda) has been put forward.
Servus non in omnibus rebus sine poena domino dicto audiens esse solet… (Glosa do Alfeni lib. secundo digestorum, D. 44.7.20)
Authors: Jurewicz Aldona Rita
Published: November 2021

In the text the author analyzes the excerpt of the work of late republican lawyer Alfenus Varus on the responsibility of slaves for the actions taken on the owner’s order. Text of Alfenus is preserved in D. 44.7.20. Its interpretation indicates that the discussed question was the private liability on the ground of lex Aquilia de damno and the perpetrator was manumitted after committing the wrongful act. The rule quoted by Alfenus, that the manumitted slaves should not be released from responsibility for the actions taken on the order of their masters, could refer to liability on the ground of the private and public law.
Criminological and Forensic Aspects of Selected Areas of Organized Crime in Poland
Authors: Bajda Karol
Published: November 2021

The article presents a criminological and forensic analysis of selected forms of contemporary organized crime in Poland, with particular emphasis on criminal terror, human trafficking, car crime, money laundering and cross-border crime. The study indicates the most important methods used by offenders in the analyzed areas from the perspective of criminology and forensics. The article aims at presenting the phenomenology (also known as symptomatology) of organized crime, including the dynamics and structure of crime in general, the methods of committing particular crimes and some elements of how the criminal world is organized. The author also points to the etiology of the characterized criminal activities. Among others, the reports on the activities of the Central Police Investigation Bureau have been used during the research. As a result of the analysis, several remarks have been formulated. First of all, the character of the presented forms of organized crime in Poland changes with time. Secondly, groups that demonstrate strictly criminal activities are still present in the public space. Thirdly, crime becomes more interdisciplinary and the criminal groups enter new areas of criminal activities. The article may form a contribution to further research in this area, including especially the development of effective mechanisms for the prevention of organized crime.
Chemisation of Agriculture in Selected Legal Acts
Authors: Żuchowska-Grzywacz Monika
Published: November 2021

The article attempts to present an analysis of the status of the concept of chemisation in selected legal acts at the international, EU and national level, and to outline the legal problems related to chemisation in agriculture. The concept of agricultural chemisation belongs to a conceptual framework of other than law branches of empirical sciences, primarily chemistry, natural sciences and agrotechnics. There is no legal definition and it is dispersed in various legal acts, significantly affecting such areas as environmental protection, food safety, food security, protection of the interests of consumers and agricultural entrepreneurs. Due to the specifics of the study, a dogmatic method was used, which analyzed the research material consisting of selected, key provisions of international and EU law and acts of national law. In order to extend the issues and emphasize the issues that are the subject of the study, the method of content analysis and analysis of documents was used, thanks to which the topicality of the discussed issue and its significant importance from the social point of view were shown. The conducted analysis was aimed at showing and emphasizing the multifaceted and complex nature of the issue.
Ograniczenia importu równoległego produktów leczniczych. Uwagi na tle wyroku Trybunału Sprawiedliwości Unii Europejskiej w sprawie C-602/19 Kohlpharma
Authors: Dudzik Jarosław
Published: November 2021

The judgement in case C-602/19 Kohlpharma is another decision of the Court of Justice of the European Union, which sets legal framework for marketing medicinal products from parallel import. By doing so, the Court continues the adjudicative tradition whereby key aspects of the issue of parallel imports of medicinal products are regulated at the level of EU law through rulings that interpret Articles 34 and 36 of the Treaty on the Functioning of the European Union (TFEU), issued in specific cases referred to the Court by the referring courts of the Member States. In the commented judgement, the Court upheld the interpretation of Articles 34 and 36 TFEU, according to which these provisions exclude the application of national regulations of a Member State, according to which the withdrawal of a reference authorisation in the importing country automatically results in the expiration of the parallel import licence. The Court also defined more precise limits to the exception contained in Article 36 TFEU concerning the protection of human health and life. This is so because it ruled that the objective of pharmacovigilance may be achieved through actions consisting in the cooperation of the competent authorities of the Member States. The commented judgement is of key importance for the assessment of compliance of Article 21a (3a) of the Polish Act – Pharmaceutical Law with the EU law. In the light of the position of the Court, this provision of the Polish law should be assessed as an excessive restriction on the freedom of movement of goods.
Abelmoschus esculentus (Bamya) Çiçeğinin Fitokimyasal Profili, Antioksidan, Antikolinerjik ve Antibakteriyel Özellikleri
Authors: KAVAZ YÜKSEL Arzu , DİKİCİ Emrah , YÜKSEL Mehmet , IŞIK Mesut
Published: November 2021

Bu araştırmanın amacı, Abelmoschus esculentus’a ait çiçek kısımınlarının etanolik ekstraktının antioksidan ve antikolinerjik özelliklerini, fenolik bileşik profilini ve antibakteriyel aktivitesini araştırmaktır. Fenolik bileşiklerin analizi LC-MS/MS ile gerçekleştirilmiştir. Antioksidan kapasitesi (radikal giderme, metal indirgeme gücü ve toplam antioksidan aktivite) DPPH, ABTS, Cu2+-Cu+ indirgeme (CUPRAC), Fe3+-Fe2+ indirgeme ve ferrik tiyosiyanat yöntemleri ile değerlendirilmiştir. Antibakteriyel aktivite, disk difüzyon ve MIC (Minimum inhibitör konsantrasyonu) yöntemleri ile belirlenmiştir. Antikolinerjik özellik ise, asetilkolinesterazın (AChE) inhibisyonu ile tespit edilmiştir. Bitki özütünde miktar bakımından en fazla bulunan başlıca fenolik bileşiğin asetohidroksamik asit olduğu belirlenmiştir. Ayrıca, sırasıyla kuarsetin, myrisetin, fumarik asit, vanillik asit, ellagik asit, 4-hidroksibenzoik asit, salisilik asit, kafeik asit, kemferol, bütein, protokateşik asit, kateşin hidrat, oleuropein ve diğer bileşenler tespit edilmiştir. Bitkinin etanolik özütü, %29.41 DPPH radikal giderme aktivitesi gösterirken, %20.59 ABTS radikal giderme aktivitesine ve ayrıca orta düzeyde metal indirgeme potansiyeline sahiptir. Ayrıca ekstrakt, 0.18 mg mL-1 IC50 değeri ile AChE üzerinde bir inhibisyon etkisi göstermiştir. Bitkinin etanol özütü, Staphylococcus aureus, Escherichia coli ve Salmonella Typhimurium üzerinde farklı düzeylerde antibakteriyel etki göstermiştir. Elde edilen sonuçlar, A. esculentus çiçek özütünün, sahip olduğu antioksidan, antikolinerjik ve antibakteriyel özellikleri ile bazı hastalıkların tedavisinde rol oynayabileceğini düşündürmektedir.
Relación entre asimetrías en diferentes pruebas de salto y lesiones musculoesqueléticas en futbolistas profesionales de Colombia
Authors: Rolong Donado Carlos , Rebolledo-Cobos Roberto Carlos
Published: November 2021

Objetivo: el objetivo del estudio fue identificar la relación entre los resultados de las pruebas saltabilidad horizontal y vertical con la incidencia las lesiones musculoesqueléticas de miembros inferiores en futbolistas de un club de la liga profesional colombiana.  Materiales y métodos: se realizó un estudio analítico, exploratorio, en 30 futbolistas de la nómina profesional del Club Deportivo Atlético Junior F.C. Al inicio de la temporada se evaluaron las características antropométricas, así mismo como la saltabilidad y asimetrías funcionales de las extremidades inferiores a través de pruebas de saltos verticales (CMJ y CMJs) y horizontales (3-Hop Test). El análisis consistió en la comparación los registros de las variables estudiadas entre los futbolistas con (lesionados n=11) y sin lesión (no lesionados n=19) en el transcurso del primer semestre de la temporada 2019.  Resultados: en los hallazgos no se encontraron diferencias estadísticas entre los grupos en las características biológicas, antropométricas y de composición corporal (p>0,05). Derivado de los hallazgos en la saltabilidad vertical, no se observaron diferencias significativas en las asimetrías funcionales entre grupos (p>0,05), sin embargo, si se encontraron diferencias en las pruebas de saltabilidad horizontal entre lesionados y no lesionados (p<0,01).  Conclusión: de este estudio podemos concluir que, en comparación a los futbolistas profesionales sin lesiones, se encontraron significativamente mayores asimetrías funcionales detectadas a través de la prueba de saltabilidad horizontal en los deportistas con lesión.
Agenesia uterina y ovárica. una combinación inusual causante de hipogonadismo hipergonadotropo (HH)
Authors: Benítez Cardoza María Clara , García Bermejo Roberto
Published: November 2021

Introducción: El Hipogonadismo Hipergonadotropo (HH) es causal de pubertad retrasada, caracterizada por afección intrínseca gonadal que interrumpe la acción del eje hipotálamo – hipófisis- gonadal. Con etiología variada, incluyendo alteraciones genéticas o adquiridas. La asociación de agenesia uterina y ovárica en una misma paciente como causa de HH es insusual. Existen casos descritos en la literatura de HH con agenesia, disgenesia, e hipoplasia ovárica, pero sin alteración uterina. Descripción del caso: Paciente de 12 años que consulta por talla baja con ausencia de desarrollo puberal. Estudios hormonales que demuestran HH. Se solicita ecografía pélvica y resonancia magnética de pelvis confirmando agenesia gonadal y uterina. Se realiza manejo con suplementos de calcio, estrógenos como sustitución hormonal para inducir caracteres sexuales secundarios y apoyo en su salud ósea.  Logra una talla final normal acorde a su talla medio parental y mejoría de su calidad de vida. Discusión: La talla baja y ausencia de caracteres sexuales secundarios, es una forma de presentación clínica de HH.  La agenesia ovárica como causa de HH, asociada a agenesia uterina en una misma paciente, es una asociación inusual, motivando la publicación del caso.  Conclusión: Es importante reconocer al HH de manera temprana, con el fin de brindar un tratamiento oportuno, y así mejorar la calidad de vida.
Pelaksanaan Pertanggungjawaban Pidana Pengedar terhadap Korban Penyalahgunaan Narkotika
Authors: Iskandar Farid
Published: November 2021

Pengedar sebagai pelaku penyalah guna narkotika telah banyak ditangkap dan dipidana, baik penjara maupun denda. Meskipun demikian penyalahgunaan narkotika dan peredarannya masih banyak ditemukan sehingga menimbulkan dugaan bahwa sanksi yang dijatuhkan kepada tersangka tidak efektif dan memiliki efek jera. Selama ini, biaya rehabilitisai bagi pecandu dan/atau korban penyalahgunaan narkotika dtanggung oleh Negara. Penelitian yuridis empiris ini dilakukan untuk mengetahui pelaksanaan sistem pertanggungjawaban pidana pengedar terhadap korban penyalahgunaan narkotika dan hambatan-hambatannya berdasarkan Undang-Undang No. 35 Tahun 2009 tentang Narkotika; serta konsep pertanggungjawaban pidana pengedar terhadap korban penyalahgunaan narkotika diterapkan di masa yang akan datang. Hasil penelitian menunjukkan fakta bahwa pelaksanaan sistem pertanggungjawaban pidana pengedar terhadap korban penyalahgunaan narkotika hanya dikenakan sanksi pidana penjara dan denda belum mengatur sanksi lain terhadap para pengedar bagi korban. Selama ini kewenangan untuk menentukan dan menjatuhkan pidana penjara atau tindakan rehabilitasi berdasarkan ketentuan peraturan perundang-undangan yang berlaku tentang narkotika berada di tangan Hakim. Konsepsi pertanggungjawaban pidana pengedar terhadap korban penyalahgunaan narkotika diterapkan di masa yang akan datang, idealnya selain pidana penjara dan denda dijatuhkan kepada pengedar, juga dibebankan biaya rehabilitasi bagi korbannya, agar biaya rehabilitasi tidak lagi dibebankan kepada negara.
Cord blood levels of uric acid, lipid profile and HOMA-IR in pregnancy induced hypertension
Authors: R. Priyadharshini , Vijayakumari V.
Published: November 2021

Background: Cardiovascular diseases (CVD) is a major global health burden that results in the greatest number of deaths worldwide. Epigenetic changes induced by pregnancy related complication in umbilical cord blood may appear as a result of dysfunctional placenta and impaired maternal cardiovascular function and may cause later onset of cardiovascular diseases in offspring.Methods: A prospective case control study was conducted at ESIC medical college, Bangalore in 100 PIH women with gestational age 37 to 40 weeks. The study aimed to find the correlation of cord blood uric acid, lipid profile and HOMA -IR in gestational hypertension mothers.Results: We found a strong positive correlation between uric acid and total cholesterol in cases and a moderate positive correlation among uric acid and LDL in cases whereas a strong negative correlation among uric acid and HDL. In addition, mean HOMA-IR value was statistically significant in cases.Conclusions: HOMA -IR values are found to be more in newborns of PIH mothers and cord blood uric acid is a good predictor of lipid metabolism and the glucose homeostasis in neonates.
Maternal and neonatal outcome of twin pregnancy at a tertiary care center
Authors: Chaudhary Vaishali , Thiyagarajan Kamalpriya , Patil Yogini , Gawali Vijaykumar
Published: November 2021

Background: Twin pregnancies occurs in 2 to 4% of the total number of births. Also the perinatal mortality and morbidity associated with it is five to six times higher in comparison with singleton pregnancy. In developing countries, 287,000 annual maternal deaths and 3 million neonatal deaths contributes to 99% of such mortality as per records of the World Health Organization (WHO) estimates that 99% of the world's annual occur in developing countries.Methods: This observational study included 50 women with twin pregnancy with gestational age of 26 weeks or more. Maternal and neonatal characteristics in twin deliveries at a tertiary care center were analyzed. High risk factors and it’s association with maternal and perinatal outcomes was analyzed.Results: Pregnancy induced hypertension (32%) was the commonest, Preterm rupture of membranes (PROM, 22%) was in the next order. Invitro fertilization (44%), malpresentation (26%) main indicators for lower segment cesarean section. Mean weight of first twin was 1.9±0.43 kg and for second twin it was 1.89±0.47kg (Table 1). Most of twins were diamniotic dichorionic (78%).Conclusions: Twin pregnancies are hazardous to both for the mother and the neonate. It is certainly high risk factor which needs early identifications of complications and timely management. Perinatal outcome largely depends on gestational age, birth weight, presentation, mode of delivery.
Intrauterine contraceptive device migration to the urinary bladder
Authors: Gavali Urmila G. , Pawar Mayuri D. , Aher Gautam S. , Shinde Suhas S.
Published: November 2021

Intravesical migration represent as uncommon complication of intrauterine device insertion. We present a case of an IUD that migrated to the urinary bladder and impacted in urinary bladder wall, causing significant urinary symptoms. A 44 years old woman presented with menorrhagia, lower abdominal pain and urinary symptoms since past 1 year. She reported an IUD insertion 10 years back. Imaging detected the presence of IUD in the urinary bladder wall with large fibroid in uterus. Under anaesthesia, total abdominal hysterectomy with bilateral salphingoophorectomy is performed and IUD was removed out of the bladder without any complications. In her follow-up evaluation after 2 week, she had no urinary symptoms. A regular follow-up of IUD for visible thread would help in earlier detection of misplaced IUD and prevent the complications such as intravesical migration.