bluuebunny/crossref_metadata_2025 huggingface dataset:
Iron overload alters the energy metabolism in patients with myelodysplastic syndromes: results from the multicenter FISM BIOFER study
Authors: Cilloni Daniela , Ravera Silvia , Calabrese Chiara , Gaidano Valentina , Niscola Pasquale , Balleari Enrico , Gallo Daniela , Petiti Jessica , Signorino Elisabetta , Rosso Valentina , Panuzzo Cristina , Sabatini Federica , Andreani Giacomo , Dragani Matteo , Finelli Carlo , Poloni Antonella , Crugnola Monica , Voso Maria Teresa , Fenu Susanna , Pelizzari Annamaria , Santini Valeria , Saglio Giuseppe , Podestà Marina , Frassoni Francesco
Published: June 2020

Myelodysplastic syndromes (MDS) are hematological malignancies characterized by ineffective hematopoiesis and increased apoptosis in the bone marrow, which cause peripheral cytopenia. Mitochondria are key regulators of apoptosis and a site of iron accumulation that favors reactive oxygen species (ROS) production with detrimental effects on cell survival. Although the energy metabolism could represent an attractive therapeutic target, it was poorly investigated in MDS. The purpose of the study was to analyze how the presence of myelodysplastic hematopoiesis, iron overload and chelation impact on mitochondrial metabolism. We compared energy balance, OxPhos activity and efficiency, lactic dehydrogenase activity and lipid peroxidation in mononuclear cells (MNCs), isolated from 38 MDS patients and 79 healthy controls. Our data show that ATP/AMP ratio is reduced during aging and even more in MDS due to a decreased OxPhos activity associated with an increment of lipid peroxidation. Moreover, the lactate fermentation enhancement was observed in MDS and elderly subjects, probably as an attempt to restore the energy balance. The biochemical alterations of MNCs from MDS patients have been partially restored by the in vitro iron chelation, while only slight effects were observed in the age-matched control samples. By contrast, the addition of iron chelators on MNCs from young healthy subjects determined a decrement in the OxPhos efficiency and an increment of lactate fermentation and lipid peroxidation. In summary, MDS-MNCs display an altered energy metabolism associated with increased oxidative stress, due to iron accumulation. This condition could be partially restored by iron chelation.
Characterization of Thermal and Electrical Transport in 6.4 nm Au Films on Polyimide Film and Fiber Substrates
Authors: Lin Huan , Kou Aijing , Cheng Jian , Dong Hua , Xu Shen , Zhang Jingkui , Luo Siyi
Published: June 2020

The surface and grain boundary scattering impact on the electrical and thermal conduction in the thin metallic films coated on organic substrates has not been studied thoroughly. In this work, we study heat and electron transport in the 6.4 nm thin Au films supported by polyimide (PI) substrate using the transient electro-thermal technique. Thermal and electrical conductivities of 6.4 nm thin Au film are much smaller than bulk value. The thermal and electrical conductivities of 6.4 nm Au film deposited on the PI fiber are reduced by 59.3% and 76.8% in the comparison with the value of bulk Au. For PI film, the reduction of thermal and electrical conductivities is 47.9% and 46.3%. Lorenz numbers of 6.4 nm Au film supported by PI fiber and PI film are 4.51 × 10−8 WΩK−2 and 2.12 × 10−8 WΩK−2, respectively. The thermal conductivities of PI fiber and PI film are 0.87 Wm−1K−1 and 0.44 Wm−1K−1. The results reveal that PI is a suitable substrate material in the flexible electronic devices field.
Elastic sowing dates with low seeding rate for grain yield maintenance in mechanized large-scale double-cropped rice production
Authors: Zheng Huabin , Li Bo , Chen Yuanwei , Tang Qiyuan
Published: June 2020

Elastic sowing dates (ESDs) are correlated with rice grain yield. ESD is the easiest factor for farmers to manipulate in mechanized large-scale farming. In this study, field experiments were conducted over a 2-year period to determine the effects of different sowing dates on growth duration, effective accumulated temperature, and yield attributes in two early- and late-season machine-transplanted rice cultivars. In early rice (ER), a delay in the sowing date led to decreased grain yield and shorter growth duration. In late rice (LR), delayed sowing led to significantly lower grain yield and prolonged growth duration. In LR, significantly positive correlations were detected between effective accumulated temperature in the post-heading stage and both filling ratio and yield. Reproductive redundancy increased markedly in LR, by 7.72% over a 5-day interval. We determined that the ESDs for LR were 10 days later than the control, and that of ER was recommend early sowing rather than late sowing. These findings suggest a new strategy to meet the demands of mechanized large-scale rice farming: the development of thermal sensitive high-yield long-duration ER cultivars and high-yield short-duration LR cultivars.
Pregnancy and neonatal outcomes of women with disabilities: a nationwide population-based study in South Korea
Authors: Shin Jae Eun , Cho Geum Joon , Bak Seongeun , Won Sang Eun , Han Sung Won , Bin Lee Soo , Oh Min-Jeong , Kim Sa Jin
Published: June 2020

We investigated (1) pregnancy and neonatal outcomes in women with and without disabilities, (2) time trends in deliveries, and (3) risks of pregnancy and neonatal complications among women with various disability types and severity. This was a nationwide population-based study merging the database of the Korea National Health Insurance claims, National Health Screening Program for Infants and Children, and Disability Registration System to compare perinatal outcomes in women with and without disabilities. Pregnancy and neonatal outcomes were analyzed during 2007 and 2015, as were time trends of deliveries. Multivariate logistic regression was used to evaluate risk of perinatal outcomes among women with various disability types and severities. Women with disabilities showed higher rates of cesarean section (aOR, 1.73; 95% CI, 1.69–1.77), hypertensive disorders (aOR, 1.74; 95% CI, 1.63–1.86), placenta abruption (aOR, 1.27; 95% CI, 1.12–1.45), placenta previa (aOR, 1.14; 95% CI, 1.05–1.24), stillbirths (aOR, 1.30; 95% CI, 1.17–1.45), preterm births (aOR, 1.67; 95% CI, 1.57–1.78), and LBW (aOR, 1.87; 95% CI, 1.78–1.97) than those without disabilities. From 2007 to 2015, although delivery rate in women with disabilities decreased steeply compared with that in women without disabilities, the rate of cesarean section increased in women with disabilities. Women with intellectual disability and those with vision impairment had the highest number of perinatal complications among women with various types of disabilities. Women with disability had more adverse pregnancy and neonatal outcomes than those without disabilities. Specific disability types & severities are more vulnerable to specific perinatal complications.
Elbasvir/grazoprevir for hepatitis C virus genotype 1b East-Asian patients receiving hemodialysis
Authors: Liu Chen-Hua , Peng Cheng-Yuan , Fang Yu-Jen , Kao Wei-Yu , Yang Sheng-Shun , Lin Cheng-Kuan , Lai Hsueh-Chou , Su Wen-Pang , Fang Sheng-Uei , Chang Chun-Chao , Su Tung-Hung , Liu Chun-Jen , Chen Pei-Jer , Chen Ding-Shinn , Kao Jia-Horng
Published: June 2020

Data regarding the efficacy and tolerability of elbasvir/grazoprevir (EBR/GZR) for East-Asian hepatitis C virus genotype 1b (HCV GT1b) patients receiving hemodialysis were limited. We prospectively recruited 40 HCV GT1b hemodialysis patients who received EBR/GZR for 12 weeks at 6 academic centers in Taiwan. The efficacy endpoints were sustained virologic response 12 weeks off-therapy (SVR12) by intention-to-treat (ITT) modified ITT (mITT) analyses. Patients’ baseline characteristics, early viral kinetics and HCV resistance-associated substitutions (RASs) at HCV non-structural 3 and 5 A (NS3 and NS5A) regions potentially affecting SVR12were analyzed. The tolerability for EBR/GZR was also assessed. The SVR12rates by ITT and mITT analyses were 95% (38 of 40 patients; 95% confidence interval (CI): 83.5–98.6%) and 100% (38 of 38 patients; 95% CI: 90.8–100%), respectively. Patients’ baseline characteristics, on-treatment viral decline, and baseline HCV RASs did not affect SVR12. All patients tolerated treatment well. Among 5 patients who had serious adverse events (AEs) including one death due to on-treatment suicide and the other death due to off-therapy acute myocardial infarction, none of these events were judged related to EBR/GZR. The common AEs included upper respiratory tract infection (7.5%), fatigue (5.0%) and anorexia (5.0%). Nine (22.5%) and 8 (20.0%) patients had on-treatment hemoglobin levels of 9.0–10.0 g/dL and 7.0–9.0 g/dL. Three (7.5%) patients had on-treatment elevated alanine aminotransferase (ALT) quotient > 2.5, in whom one (2.5%) had EBR/GZR-induced late ALT elevation. No patients developed hyperbilirubinemia or hepatic decompensation. In conclusion, treatment with EBR/GZR is effective and well-tolerated for East-Asian HCV GT1b patients receiving hemodialysis.
Author Correction: Phase variation in pneumococcal populations during carriage in the human nasopharynx
Authors: Croix M. De Ste , Mitsi E. , Morozov A. , Glenn S. , Andrew P. W. , Ferreira D. M. , Oggioni M. R.
Published: June 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer
Authors: Sigin Vladimir O. , Kalinkin Alexey I. , Kuznetsova Ekaterina B. , Simonova Olga A. , Chesnokova Galina G. , Litviakov Nikolai V. , Slonimskaya Elena M. , Tsyganov Matvey M. , Ibragimova Marina K. , Volodin Ilya V. , Vinogradov Ilya I. , Vinogradov Maksim I. , Vinogradov Igor Y. , Kutsev Sergey I. , Strelnikov Vladimir V. , Zaletaev Dmitry V. , Tanas Alexander S.
Published: June 2020

Despite the advantages of neoadjuvant chemotherapy (NACT), associated toxicity is a serious complication that renders monitoring of the patients’ response to NACT highly important. Thus, prediction of tumor response to treatment is imperative to avoid exposure of potential non-responders to deleterious complications. We have performed genome-wide analysis of DNA methylation by XmaI-RRBS and selected CpG dinucleotides differential methylation of which discriminates luminal B breast cancer samples with different sensitivity to NACT. With this data, we have developed multiplex methylation sensitive restriction enzyme PCR (MSRE-PCR) protocol for determining the methylation status of 10 genes (SLC9A3, C1QL2, DPYS, IRF4, ADCY8, KCNQ2, TERT, SYNDIG1, SKOR2 and GRIK1) that distinguish BC samples with different NACT response. Analysis of these 10 markers by MSRE-PCR in biopsy samples allowed us to reveal three top informative combinations of markers, (1) IRF4 and C1QL2; (2) IRF4, C1QL2, and ADCY8; (3) IRF4, C1QL2, and DPYS, with the areas under ROC curves (AUCs) of 0.75, 0.78 and 0.74, respectively. A classifier based on IRF4 and C1QL2 better meets the diagnostic panel simplicity requirements, as it consists of only two markers. Diagnostic accuracy of the panel of these two markers is 0.75, with the sensitivity of 75% and specificity of 75%.
Assessing the costs of historical inaction on climate change
Authors: Sanderson Benjamin M. , O’Neill Brian C.
Published: June 2020

We consider alternative history scenarios in which explicit climate mitigation begins before the present day, estimating the total costs to date of delayed action. Considering a 2(1.5) degree Celsius stabilization target, peak costs are greater and reached sooner with a later start to mitigation, reaching 15(17)% of global GDP in 2085(2070) for a 1990 start and 18(35)% in 2080(2035) for a 2020 start. Further mitigation delay costs a best estimate of an additional 0.5(5) trillion dollars per year. Additional simulations show how optimal mitigation pathways evolve without imposing a warming limit, finding that median abatement levels and costs are not strongly dependent on start date. However, whereas 18(5) percent of optimal solutions starting in 1980 meet the 2(or 1.5) degree target, 5(or 0)% of 2020 simulations meet the goals. Discounted damages due to delayed mitigation action rise by 0.6 trillion US dollars per year in 2020.
Experimental realization of Lieb-Mattis plateau in a quantum spin chain
Authors: Yamaguchi Hironori , Okita Taiki , Iwasaki Yoshiki , Kono Yohei , Uemoto Nao , Hosokoshi Yuko , Kida Takanori , Kawakami Takashi , Matsuo Akira , Hagiwara Masayuki
Published: June 2020

Topological properties in material science have recently received tremendous attention, as exemplified by topological insulators. As for quantum spin systems, the Haldane chain with integer spins is the best known example1. The realization of a topological quantum phase in the Haldane chain is an innovative research development related to the 2016 Nobel Prize in Physics. For mixed spin chains composed of two different spins, the appearance of a topologically quantized magnetization plateau is predicted by the Lieb-Mattis theorem2 in combination with the Oshikawa-Yamanaka-Affleck criterion3. However, the actual magnetization plateau in the mixed spin chain has not yet been observed. Here, we present a model compound forming a mixed spin-(1/2, 5/2) chain. We observe a clear Lieb-Mattis plateau and well explain it quantitatively. The present results demonstrate a quantum many-body effect based on quantum topology and provide a new stage in the search for topological properties in condensed matter physics.
Author Correction: Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
Authors: Thieker David F. , Xu Yongmei , Chapla Digantkumar , Nora Chelsea , Qiu Hong , Felix Thomas , Wang Lianchun , Moremen Kelley W. , Liu Jian , Esko Jeffrey D. , Woods Robert J.
Published: June 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Structural trends in atomic nuclei from laser spectroscopy of tin
Authors: Yordanov Deyan T. , Rodríguez Liss V. , Balabanski Dimiter L. , Bieroń Jacek , Bissell Mark L. , Blaum Klaus , Cheal Bradley , Ekman Jörgen , Gaigalas Gediminas , Garcia Ruiz Ronald F. , Georgiev Georgi , Gins Wouter , Godefroid Michel R. , Gorges Christian , Harman Zoltán , Heylen Hanne , Jönsson Per , Kanellakopoulos Anastasios , Kaufmann Simon , Keitel Christoph H. , Lagaki Varvara , Lechner Simon , Maaß Bernhard , Malbrunot-Ettenauer Stephan , Nazarewicz Witold , Neugart Rainer , Neyens Gerda , Nörtershäuser Wilfried , Oreshkina Natalia S. , Papoulia Asimina , Pyykkö Pekka , Reinhard Paul-Gerhard , Sailer Stefan , Sánchez Rodolfo , Schiffmann Sacha , Schmidt Stefan , Wehner Laura , Wraith Calvin , Xie Liang , Xu Zhengyu , Yang Xiaofei
Published: June 2020

Tin is the chemical element with the largest number of stable isotopes. Its complete proton shell, comparable with the closed electron shells in the chemically inert noble gases, is not a mere precursor to extended stability; since the protons carry the nuclear charge, their spatial arrangement also drives the nuclear electromagnetism. We report high-precision measurements of the electromagnetic moments and isomeric differences in charge radii between the lowest 1/2+, 3/2+, and 11/2− states in 117–131Sn, obtained by collinear laser spectroscopy. Supported by state-of-the-art atomic-structure calculations, the data accurately show a considerable attenuation of the quadrupole moments in the closed-shell tin isotopes relative to those of cadmium, with two protons less. Linear and quadratic mass-dependent trends are observed. While microscopic density functional theory explains the global behaviour of the measured quantities, interpretation of the local patterns demands higher-fidelity modelling.
A ligation-triggered and protein-assisted fluorescence anisotropy amplification platform for sensitive and selective detection of small molecules in a biological matrix
Authors: Chen Meizi , Wan Bing , Du Wei , Hu Hongbo , Zeng Long , Duan Xintong , Liu Jia , Wei Zixiang , Tang Li , Peng Yongbo
Published: June 2020

A ligation-triggered and protein-assisted fluorescence anisotropy amplification platform has been developed for sensitive and selective detection of small molecules in a biological matrix.
Insight into structural properties of polyethylene glycol monolaurate in water and alcohols from molecular dynamics studies
Authors: Khoiroh Ianatul , Lee Sze Ying , Pirdashti Mohsen , Lee Ming-Jer
Published: June 2020

By means of molecular dynamics (MD) simulations, we explored the structural properties of polyethylene glycol monolaurate (PEGML) in water and in various aliphatic alcohols (methanol, ethanol, 2-propanol, 2-butanol, tert-butanol, and 1-pentanol).
Identification of on- and off-pathway oligomers in amyloid fibril formation
Authors: Dear Alexander J. , Meisl Georg , Šarić Anđela , Michaels Thomas C. T. , Kjaergaard Magnus , Linse Sara , Knowles Tuomas P. J.
Published: June 2020

A general non-binary definition for on- and off-pathway intermediates is developed, enabling comparison of amyloid oligomers' contributions to fibril formation.
Multiplex-invasive reaction-assisted qPCR for quantitatively detecting the abundance of EGFR exon 19 deletions in cfDNA
Authors: Tang Yunmei , Zou Bingjie , Wang Runyuan , Luo Nan , Qi Xiemin , Zhou Guohua , Song Qinxin
Published: June 2020

This method achieved simultaneously quantifying 19 kinds of exon 19 deletions on EGFR gene in a single tube by multiplex invasive reaction-assisted real-time PCR.
SAXS signature of the lamellar ordering of ionic domains of perfluorinated sulfonic-acid ionomers by electric and magnetic field-assisted casting
Authors: da Silva Jaqueline S. , Carvalho Sabrina G. M. , da Silva Rodrigo P. , Tavares Ana C. , Schade Ulrich , Puskar Ljiljana , Fonseca Fabio C. , Matos Bruno R.
Published: June 2020

The origins of the matrix and ionomer peaks of Nafion SAXS pattern are revisited.
Significant tunneling magnetoresistance and excellent spin filtering effect in CrI3-based van der Waals magnetic tunnel junctions
Authors: Yan Zhi , Zhang Ruiqiang , Dong Xinlong , Qi Shifei , Xu Xiaohong
Published: June 2020

The transport properties of CrI3/h-BN/n·CrI3 (n = 1, 2, 3, 4) MTJs under positive bias voltages exhibit an interesting odd-even effect. Significant tunneling magnetoresistance, a perfect spin filtering effect and remarkable negative differential resistance were obtained.
Effect of chemisorbed thiophenols with an electron donating group on surface-enhanced Raman scattering of gold nanorods
Authors: Seo Min Jung , Ryu Kyeong Rim , Kim Geun Wan , Ha Ji Won
Published: June 2020

The surface-enhanced Raman scattering (SERS) enhancement with electron donating group (EDG) is caused by the formation of aggregates through intermolecular interactions among probe molecules.
First-principles insight into CO hindered agglomeration of Rh and Pt single atoms on m-ZrO2
Authors: Kauppinen Minttu M. , Melander Marko M. , Honkala Karoliina
Published: June 2020

Kinetic and thermodynamic stability of single-atom and nanocluster catalysts is addressed under reaction conditions within a DFT-parametrised multi-scale thermodynamic framework combining atomistic, non-equilibrium, and nanothermodynamics.
Strong metal–support interactions in Pd/Co3O4 catalyst in wet methane combustion: in situ X-ray absorption study
Authors: Barrett William , Nasr Somaye , Shen Jing , Hu Yongfeng , Hayes Robert E. , Scott Robert W. J. , Semagina Natalia
Published: June 2020

CoOx inhibits Pd oxidation in CH4 combustion in the wet feed.
Boosting C2 products in electrochemical CO2 reduction over highly dense copper nanoplates
Authors: Ajmal Saira , Yang Yang , Tahir Muhammad Ali , Li Kejian , Bacha Aziz-Ur-Rahim , Nabi Iqra , Liu Yangyang , Wang Tao , Zhang Liwu
Published: June 2020

Exclusive C2 selectivity of Cu-Nplates over C1 during electrocatalytic CO2 reduction offers opportunities for large scale, long-term renewable energy storage and lessens carbon emissions.
Realizing record high performance in n-type Bi2Te3-based thermoelectric materials
Authors: Zhu Bin , Liu Xixi , Wang Qi , Qiu Yang , Shu Zhong , Guo Zuteng , Tong Yao , Cui Juan , Gu Meng , He Jiaqing
Published: June 2020

High performance BiTeSe alloys and modules with a conversion efficiency of 6.6% are achieved through potential wells and multi-scale structures.
Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Authors: Pecson Brian , Gerrity Daniel , Bibby Kyle , Drewes Jörg E. , Gerba Charles , Gersberg Richard , Gonzalez Raul , Haas Charles N. , Hamilton Kerry A. , Nelson Kara L. , Olivieri Adam , Rock Channah , Rose Joan , Sobsey Mark
Published: June 2020

Brian Pecson and Daniel Gerrity present an Editorial Perspective which focuses on the impact of SARS-CoV-2 on the water industry.
Enhancement of organic solar cell performance by incorporating gold quantum dots (AuQDs) on a plasmonic grating
Authors: Phetsang Sopit , Nootchanat Supeera , Lertvachirapaiboon Chutiparn , Ishikawa Ryousuke , Shinbo Kazunari , Kato Keizo , Mungkornasawakul Pitchaya , Ounnunkad Kontad , Baba Akira
Published: June 2020

The performance of organic solar cells was improved by the effect of a synergistic gold quantum dot/plasmonic grating system.
Coaxial nanofibers outperform uniaxial nanofibers for the loading and release of pyrroloquinoline quinone (PQQ) for biomedical applications
Authors: Ibrahim Sara , Rezk Marwan Y. , Ismail Mohammed , Abdelrahman Taghrid , Sharkawy Mona , Abdellatif Ahmed , Allam Nageh K.
Published: June 2020

Pyrroloquinoline quinone (PQQ), present in breast milk and various foods, is highly recommended as an antioxidant, anti-inflammatory agent, and a cofactor in redox reactions in several biomedical fields.
Catalytic combustion of toluene over CeO2–CoOx composite aerogels
Authors: Miao Chao , Liu Junjie , Zhao Jinxian , Quan Yanhong , Li Tao , Pei Yongli , Li Xiaoliang , Ren Jun
Published: June 2020

The dispersion of active species and redox cycle of Co3+/Co2+ in cobalt based aerogels have an important influence on catalytic performance for toluene oxidation.
A novel column fabrication approach for capillary gas chromatography via a cross-linked organogel network with high stability and inertness
Authors: Xiong Xue , Qi Meiling
Published: June 2020

A new column fabrication approach for capillary gas chromatography with high column selectivity, stability and inertness.
Structure–reactivity relationship of probes based on the H2S-mediated reductive cleavage of the CC bond
Authors: Wang Chunfei , Tan Jingyun , Zhang Xuanjun
Published: June 2020

The structure–reactivity relationship of H2S-mediated reductive cleavage of CC bond was studied and utilized to develop probes for detecting H2S.
Single plasmon spatial and spectral sorting on a crystalline two-dimensional plasmonic platform
Authors: Kumar Upkar , Bolisetty Sreenath , Mezzenga Raffaele , Girard Christian , Dujardin Erik , Cuche Aurélien
Published: June 2020

We demonstrate the spatial and spectral sorting of single plasmon excited by a quantum nanoemitter on a crystalline two-dimensional plasmonic gold flake.
Demonstration of k-vector selective microscopy for nanoscale mapping of higher order spin wave modes
Authors: Träger Nick , Gruszecki Paweł , Lisiecki Filip , Groß Felix , Förster Johannes , Weigand Markus , Głowiński Hubert , Kuświk Piotr , Dubowik Janusz , Krawczyk Maciej , Gräfe Joachim
Published: June 2020

Time resolved STXM provides deep insights into efficient excitation of symmetric and antisysmmetric higher order spin wave modes in magnonic waveguides. k-selective imaging reveals real space information of simultaneously excited mode patterns.
AgPd nanoparticles for electrocatalytic CO2 reduction: bimetallic composition-dependent ligand and ensemble effects
Authors: Cui Meiyang , Johnson Grayson , Zhang Zhiyong , Li Shuang , Hwang Sooyeon , Zhang Xu , Zhang Sen
Published: June 2020

By balancing bimetallic composition-associated ligand and ensemble effects, Ag15Pd85 nanoparticles show enhanced catalytic properties for electrochemical CO2 reduction.
Toxicity and mechanism of mesoporous silica nanoparticles in eyes
Authors: Chen Xia , Zhu Shuang , Hu Xisu , Sun Dayu , Yang Junling , Yang Cao , Wu Wei , Li Yijian , Gu Xianliang , Li Minghui , Liu Bo , Ge Lingling , Gu Zhanjun , Xu Haiwei
Published: June 2020

It aims to explore the toxicity and mechanism of large-surface-area MSiNPs and MSiNPs-Ag+ exposed to hCEC cells and cornea. A protein corona-based therapy was proposed to treat MSiNPs and MSiNPs-Ag+ induced corneal damage and dry eye.
Triarylmethanolation as a versatile strategy for the conversion of PAHs into amorphization-induced emission luminogens for extremely sensitive explosive detection and fabrication of artificial light-harvesting systems
Authors: Su Min , Jing Ya-Nan , Bao Hongli , Wan Wen-Ming
Published: June 2020

A triarylmethanolation strategy has been reported for the molecular design of luminescent materials with amorphization-induced emission, which exhibit sensitive explosive detection and aid in the fabrication of artificial light-harvesting systems.
Synthesis of polysubstituted 5-trifluoromethyl isoxazoles via denitrogenative cyclization of vinyl azides with trifluoroacetic anhydride
Authors: Wu Wei , Chen Qiaoling , Tian Yishi , Xu Yihui , Huang Yangjie , You Yi , Weng Zhiqiang
Published: June 2020

A general method for the synthesis of 5-(trifluoromethyl)isoxazoles by denitrogenative cyclization of vinyl azides with trifluoroacetic anhydride has been developed.
A bow-free freestanding GaN wafer
Authors: Shim Jae-Hyoung , Park Jin-Seong , Park Jea-Gun
Published: June 2020

For applications as high-brightness light-emitting-diodes, a bow-free freestanding gallium nitride was fabricated by process-designing pit and mirror GaN layers grown via hydride-vapor-phase epitaxy, followed by several polishing and etching methods.
SERS-active substrate assembled by Ag NW-embedded porous polystyrene fibers
Authors: Chen Shulin , Ding Chen , Lin Yong , Wu Xinzhou , Yuan Wei , Meng Xiuqing , Su Wenming , Zhang Ke-Qin
Published: June 2020

SERS-active substrate assembled by Ag NW-embedded porous PS fibers has high sample collection efficiency for the target molecule.
Thermo-oxidative stability and flammability properties of bamboo/kenaf/nanoclay/epoxy hybrid nanocomposites
Authors: Chee Siew Sand , Jawaid Mohammad , Alothman Othman Y. , Yahaya Ridwan
Published: June 2020

In this study, three types of nanoclay [halloysite nanotube (HNT), montmorillonite (MMT) and organically modified MMT (OMMT)] were incorporated into bamboo/kenaf (B/K) reinforced epoxy hybrid composites to compare their thermo-oxidative (TOD) stability and flammability properties.
A novel ethanol gas sensor based on α-Bi2Mo3O12/Co3O4 nanotube-decorated particles
Authors: Din Salah Ud , Haq Mahmood ul , Khatoon Rabia , Chen Xuehua , Li Li , Zhang Manjun , Zhu Liping
Published: June 2020

A novel composite based on α-Bi2Mo3O12/Co3O4 nanotube-decorated particles was successfully synthesized using a highly efficient and facile two step system using electrospinning and hydrothermal techniques.
Damage mechanism and electro-elastic stability of LiNbO3 crystals irradiated with 6 MeV Xe23+
Authors: Tian Shiwei , Jiang Chao , Chen Feifei , Yu Fapeng , Li Yanlu , Cheng Xiufeng , Wang Zhengping , Zhao Xian
Published: June 2020

Bulk LiNbO3 (LN) crystals could maintain their electrical and electro-elastic properties even under hard irradiation.
Synthesis and molecular modeling studies of cholinesterase inhibitor dispiro[indoline-3,2′-pyrrolidine-3′,3′′-pyrrolidines]
Authors: Youssef M. Adel , Panda Siva S. , El-Shiekh Riham A. , Shalaby ElSayed M. , Aboshouk Dalia R. , Fayad Walid , Fawzy Nehmedo G. , Girgis Adel S.
Published: June 2020

Dispiro[indoline-3,2′-pyrrolidine-3′,3′′-pyrrolidines] were regioselectively synthesized revealing cholinesterase (AChE, BChE) inhibitory properties.
New insights in the physicochemical investigation of the vitamin B12 nucleus using statistical physics treatment: interpretation of experiments and surface properties
Authors: Ben Yahia Manel , Ben Yahia Mohamed
Published: June 2020

Quartz Crystal Microbalance (QCM) setup for the measurement of adsorption isotherms of cobalt(ii)nitrate and cobalt(ii)chloride on tetrakis(4-tolylphenyl)porphyrin (H2TTPP).
Synthesis of 2,5-furandicarboxylic acid by a TEMPO/laccase system coupled with Pseudomonas putida KT2440
Authors: Zou Lihua , Zheng Zhaojuan , Tan Huanghong , Xu Qianqian , Ouyang Jia
Published: June 2020

A novel biological approach for the production of FDCA by a TEMPO/laccase system coupled with Pseudomonas putida KT2440 was established.
Electron beam irradiation for the formation of thick Ag film on Ag3PO4
Authors: Paulo de Campos da Costa João , Assis Marcelo , Teodoro Vinícius , Rodrigues Andre , Cristina de Foggi Camila , San-Miguel Miguel Angel , Pereira do Carmo João Paulo , Andrés Juan , Longo Elson
Published: June 2020

This study demonstrates that the electron beam irradiation of materials, typically used in characterization measurements, could be employed for advanced fabrication, modification, and functionalization of composites.
Recent advances in the design of cathode materials for Li-ion batteries
Authors: Mohamed Nourhan , Allam Nageh K.
Published: June 2020

It is crucial to design new innovative materials to boost the performance of Li-ion batteries.
Application of polyethylenimine-coated magnetic nanocomposites for the selective separation of Cs-enriched clay particles from radioactive soil
Authors: Kim June-Hyun , Kim Sung-Man , Yoon In-Ho , Kim Ilgook
Published: June 2020

Selective separation of Cs-enriched fine particles from contaminated soil using Fe3O4-PEI nanocomposites and a mesh filter.
3D printing of biomass-derived composites: application and characterization approaches
Authors: Ji Anqi , Zhang Shuyang , Bhagia Samarthya , Yoo Chang Geun , Ragauskas Arthur J.
Published: June 2020

Biomass-derived 3D printing has attracted interests because of its developing technology and availability with renewable materials as well as compatible characteristics for many applications.
A highly green approach towards aromatic nitro group substitutions: catalyst free reactions of nitroimidazoles with carbon nucleophiles in water
Authors: Shah Syed Raza , Ali Muhammad , Anwar Muhammad U. , Al-Harrasi Ahmed
Published: June 2020

We have successfully developed a flexible green aqueous approach for the formation of a carbon–carbon bond by the reaction of highly-enolizable carbanions (mostly derived from 1,3-dicarbonyl compounds) with an aromatic carbon bearing a nitro group.
Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers
Authors: Banchelli Martina , Cascella Roberta , D'Andrea Cristiano , Cabaj Leszek , Osticioli Iacopo , Ciofini Daniele , Li Mai Suan , Skupień Krzysztof , de Angelis Marella , Siano Salvatore , Cecchi Cristina , Pini Roberto , La Penna Giovanni , Chiti Fabrizio , Matteini Paolo
Published: June 2020

Unraveling characteristic structural determinants at the basis of Aβ42 oligomers' neurotoxicity by a sub-molecular SERS investigation of their surface.
SWCNT–porphyrin nano-hybrids selectively activated by ultrasound: an interesting model for sonodynamic applications
Authors: Bosca Federica , Corazzari Ingrid , Foglietta Federica , Canaparo Roberto , Durando Gianni , Pastero Linda , Arpicco Silvia , Dosio Franco , Zonari Daniele , Cravotto Giancarlo , Tagliapietra Silvia , Serpe Loredana , Turci Francesco , Barge Alessandro
Published: June 2020

Sonodynamic therapy (SDT) is an innovative anticancer approach, based on the excitation of a given molecule (usually a porphyrin) by inertial acoustic cavitation that leads to cell deathviathe production of reactive oxygen species (ROS).
The genus Micromonospora as a model microorganism for bioactive natural product discovery
Authors: Hifnawy Mohamed S. , Fouda Mohamed M. , Sayed Ahmed M. , Mohammed Rabab , Hassan Hossam M. , AbouZid Sameh F. , Rateb Mostafa E. , Keller Alexander , Adamek Martina , Ziemert Nadine , Abdelmohsen Usama Ramadan
Published: June 2020

We explore the genus Micromonospora as a model for natural product research and the discovery progress from the classical bioassay-guided approaches through to the application of genome mining and genetic engineering techniques that target specific products.
Elucidating sensing mechanisms of a pyrene excimer-based calix[4]arene for ratiometric detection of Hg(ii) and Ag(i) and chemosensor behaviour as INHIBITION or IMPLICATION logic gates
Authors: Rodríguez-Lavado Julio , Lorente Alejandro , Flores Erick , Ochoa Andrés , Godoy Fernando , Jaque Pablo , Saitz Claudio
Published: June 2020

This article reports the synthesis and characterisation of two lower rim calix[4]arene derivatives with thiourea as spacer and pyrene or methylene-pyrene as fluorophore.
Crystal structure, optical spectroscopy and energy transfer properties in NaZnPO4:Ce3+, Tb3+ phosphors for UV-based LEDs
Authors: Saidi K. , Dammak M.
Published: June 2020

A series of Ce3+, Tb3+ and, Ce3+/Tb3+ doped NaZnPO4(NZPO) phosphors synthesized via the high-temperature solid-state reaction method were investigated.
Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
Authors: Sarkar Abhijnan , Formenti Dario , Ferretti Francesco , Kreyenschulte Carsten , Bartling Stephan , Junge Kathrin , Beller Matthias , Ragaini Fabio
Published: June 2020

An Fe-based heterogeneous catalyst allows for the synthesis of cyclopropanes via a carbene transfer reaction, a transformation usually belonging to the homogeneous domain.
Understanding the electrochemistry of “water-in-salt” electrolytes: basal plane highly ordered pyrolytic graphite as a model system
Authors: Iamprasertkun Pawin , Ejigu Andinet , Dryfe Robert A. W.
Published: June 2020

The stability of water-in-salt electrolyte systems is investigated using highly concentrated solutions of KF(aq) with graphite as a model system.
Charge transfer characteristics of fullerene-free polymer solar cells via multi-state electronic coupling treatment
Authors: Kastinen Tuuva , Hukka Terttu I.
Published: June 2020

Dispersion-corrected optimally tuned long-range corrected functional provides constant electronic couplings for non-fullerene polymer solar cell systems regardless of the number of the excited states included in the calculations.
A multifunctional CuSCN interlayer in carbon electrode-based CsPbIBr2 all-inorganic perovskite solar cells for boosting the efficiency and stability
Authors: Liu Jieqiong , Lei Miao , Zhang Wei , Wang Guiqiang
Published: June 2020

A multifunctional CuSCN interlayer boosts the efficiency and stability of carbon electrode-based CsPbIBr2 all-inorganic perovskite solar cells.
Improved charge carrier dynamics of WS2 nanostructures by the way of CdS@WS2 heterostructures for use in water splitting and water purification
Authors: Velpandian Muthuraja , Pulipaka Supriya , Tikoo Akshay , Meduri Praveen
Published: June 2020

Long emission decay life time and significantly quenched fluorescence emission of tungsten disulfide (WS2)/cadmium sulfide (CdS) heterostructures aid in enhancing photoelectrochemical water splitting and water purification properties.
Characterization of a new rechargeable Zn/PVA-KOH/Bi2O3 battery: structural changes of the Bi2O3 electrode
Authors: Lorca Sebastián , Santos Florencio , Abad José , Huttel Yves , Urbina Antonio , Fernández Romero Antonio J.
Published: June 2020

A new rechargeable Zn/PVA-KOH/Bi2O3 with coulombic efficiencies of 100% and energy efficiencies above 80% for a high number of cycles.
Fluorination of a polymer donor through the trifluoromethyl group for high-performance polymer solar cells
Authors: Yao Chao , Zhu Yanan , Gu Kaichen , Zhao Jiajun , Ning Jiaoyi , Perepichka Dmitrii F. , Loo Yueh-Lin , Meng Hong
Published: June 2020

Polymer donor F0 is fluorinated to F1 through converting methyl group to trifluoromethyl group on side chains. F1 exhibits remarkably improved performance in polymer solar cells with a highest PCE of 13.5%.
Ligand modification of Cu2ZnSnS4 nanoparticles boosts the performance of low temperature paintable carbon electrode based perovskite solar cells to 17.71%
Authors: Cao Yang , Li Weiwei , Liu Zhen , Zhao Zhiqiang , Xiao Zhenyu , Zi Wei , Cheng Nian
Published: June 2020

Ligand modified Cu2ZnSnS4 (CZTS) nanoparticles have been demonstrated to be a potential hole transporting material for low temperature paintable carbon electrode based perovskite solar cells, which exhibit a champion PCE of 17.71%.
A crosslinked conducting polymer with well-defined proton trap function for reversible proton cycling in aprotic environments
Authors: Åkerlund Lisa , Emanuelsson Rikard , Hernández Guiomar , Strømme Maria , Sjödin Martin
Published: June 2020

In this paper, a well-defined proton trap material containing a hydroquinone unit flanked by two pyridine proton acceptors is presented.
Layer conductance reduction and failure analysis due to bending for superflexible perovskite solar cells
Authors: Xie Ziang , Xu Wanjin , Sun Shuren , Xie Xixi , Li Yanping , Qin G. G.
Published: June 2020

In flexible perovskite solar cells, layer conductance reductions of constituent layers are found to be essential for PCE reduction due to bending.
A vessel subtype beneficial for osteogenesis enhanced by strontium-doped sodium titanate nanorods by modulating macrophage polarization
Authors: Guo Shuo , Yu Dongmei , Xiao Xin , Liu Wenwen , Wu Zhigang , Shi Lei , Zhao Quanming , Yang Di , Lu Yajie , Wei Xinghui , Tang Zhen , Wang Ning , Li Xiaokang , Han Yong , Guo Zheng
Published: June 2020

Early vascularization plays an important role in bone healing, especially in interfacial bone formation.
Nanoporous gold peel-and-stick biosensors created with etching inkjet maskless lithography for electrochemical pesticide monitoring with microfluidics
Authors: Hondred John A. , Johnson Zachary T. , Claussen Jonathan C.
Published: June 2020

Flexible nanoporous gold and silver leaf are patterned without photolithography and adhered to microfluidics to create disposable multiplexed electrochemical biosensors.
FRET-enhanced photoluminescence of perylene diimides by combining molecular aggregation and insulation
Authors: Zhang Bolong , Lyskov Igor , Wilson Lachlan J. , Sabatini Randy P. , Manian Anjay , Soleimaninejad Hamid , White Jonathan M. , Smith Trevor A. , Lakhwani Girish , Jones David J. , Ghiggino Kenneth P. , Russo Salvy P. , Wong Wallace W. H.
Published: June 2020

Samples containing both molecularly insulated and aggregated perylene diimides at high concentration (140 mM) in polymer matrix showed very high photoluminescence quantum yield (85%) as a result of efficient energy transfer.
Turnaround radius of galaxy clusters in N-body simulations
Authors: Korkidis Giorgos , Pavlidou Vasiliki , Tassis Konstantinos , Ntormousi Evangelia , Tomaras Theodore N. , Kovlakas Konstantinos
Published: June 2020

Aims. We use N-body simulations to examine whether a characteristic turnaround radius, as predicted from the spherical collapse model in a ΛCDM Universe, can be meaningfully identified for galaxy clusters in the presence of full three-dimensional effects.

Methods. We use The Dark Sky Simulations and Illustris-TNG dark-matter-only cosmological runs to calculate radial velocity profiles around collapsed structures, extending out to many times the virial radius R200. There, the turnaround radius can be unambiguously identified as the largest nonexpanding scale around a center of gravity.

Results. We find that: (a) a single turnaround scale can meaningfully describe strongly nonspherical structures. (b) For halos of masses M200 >  1013 M⊙, the turnaround radius Rta scales with the enclosed mass Mta as Mta1/3, as predicted by the spherical collapse model. (c) The deviation of Rta in simulated halos from the spherical collapse model prediction is relatively insensitive to halo asphericity. Rather, it is sensitive to the tidal forces due to massive neighbors when these are present. (d) Halos exhibit a characteristic average density within the turnaround scale. This characteristic density is dependent on cosmology and redshift. For the present cosmic epoch and for concordance cosmological parameters (Ωm ∼ 0.3; ΩΛ ∼ 0.7) turnaround structures exhibit a density contrast with the matter density of the background Universe of δ ∼ 11. Thus, Rta is equivalent to R11 – in a way that is analogous to defining the “virial” radius as R200 – with the advantage that R11 is shown in this work to correspond to a kinematically relevant scale in N-body simulations.
Composition dependence of thermo-dynamical and thermo-mechanical properties in SeTeSnGe chalcogenide glasses (ChGs)
Authors: Pal Shiv Kumar , Mehta Neeraj , MacDonald John C. , Sharma Dipti
Published: June 2020

In this endeavor, we have synthesized novel quaternary glassy Se78-xTe20Sn2Gex (0 ≤ x ≤ 6) alloys by the well-known rapid cooling of melt under quenching technique, to study the effect of Germanium on thermodynamic and thermo-mechanical properties. In particular, we employed Differential Scanning Calorimetry (DSC) technique for the investigation of thermodynamic parameters (e.g., specific heat Cp
and enthalpy ΔH) in the glass-transition-region (GTR). Differential Scanning Calorimetry (DSC) experiment was run under non-isothermal conditions. The thermo-mechanical parameters i.e., micro-hardness, micro-void volume, the energy of creation of micro-void, elasticity, density, compactness, and molar volume are also calculated. It was observed that there is a large increment in Cp
values in the GTR. Further analysis shows that the Cp
values above the GTR (i.e., Cp
 = Cpe
equilibrium specific heat) and below the GTR (i.e., Cp
 = Cpg
glass specific heat) are vastly composition dependent. The increment in specific heat value after Ge incorporation is explained in terms of molar volume.
Epidemiologisches Update: Aktuelles zur epidemiologischen Situation
der alveolären Echinokokkose und deren Erfassungs- und Meldestrukturen
in Österreich, der Schweiz und Deutschland
Authors: Schmidberger Julian , Baumann Sven , Kratzer Wolfgang , Schlingeloff Patrycja , Lachmann Raskit , Stark Klaus , Peters Lynn , Gruener Beate , Ramharter Michael , Hoepffner Philip Jens , Strohäker Jens , Blum Anna , Müllhaupt Beat , Lagler Heimo
Published: June 2020

Ziel der Studie Die alveoläre Echinokokkose (AE) ist in
Österreich, der Schweiz und Deutschland (DACh) eine seltene Erkrankung,
welche durch eine Infektion mit dem Parasiten Echinococcus multilocularis
hervorgerufen werden kann. Ziel der Arbeit ist die Darstellung von Unterschieden
im Erfassungs- und Meldesystem der alveolären Echinokokkose in
Österreich, der Schweiz und Deutschland und der Beschreibung der
epidemiologischen Entwicklungen und deren Trends.

Methodik Im Rahmen eines Epidemiologischen Updates am 06. September 2019
in Ulm, Deutschland diskutierten Experten und Repräsentanten
über Unterschiede im Melde- und Erfassungssystem sowie über die
aktuelle epidemiologische Situation.

Ergebnisse In Österreich besteht seit 2004 nach §1 Abs. 1
eine namentliche Meldepflicht nach dem Epidemiegesetz 1950 (EpidemieG) und der
Verordnung gemäß der anzeigepflichtig übertragbarer
Krankheiten für Verdachts-, Erkrankungs- und Todesfälle
für eine alveoläre Echinokokkose. Nach §7 Abs. 3
Infektionsschutzgesetz (IfSG) besteht für Deutschland seit 2001
ebenfalls eine Meldepflicht, allerdings nichtnamentlich. Zusätzlich
stehen in beiden Ländern nationale Register bereit, welche für
die Beantwortung wissenschaftlicher Fragen genutzt werden können. In der
Schweiz besteht seit 1997 keine Meldepflicht mehr für die humane
alveoläre Echinokokkose. Derzeit bestehen Bestrebungen für die
zeitnahe Implementierung eines nationalen Registers für die
alveoläre Echinokokkose in der Schweiz. Trotz unterschiedlicher Melde-
und Erfassungssysteme zeigt sich für DACh ein ähnlicher
epidemiologischer Trend.

Schlussfolgerungen In Österreich, der Schweiz und Deutschland
zeigt sich ein leicht steigender Trend von humanen Erkrankungsfällen mit
alveolärer Echinokokkose. Die direkte Vergleichbarkeit ist aufgrund
unterschiedlicher Meldepflichten und deren Strukturen eingeschränkt und
erlaubt häufig nicht die gemeinschaftliche Beantwortung
wissenschaftlicher Fragestellungen zur Diagnostik, Behandlung und
Versorgung.
Hefte, die helfen, und Bilder, die ansprechen
Authors: Schnabel Anna , Kocks Andreas
Published: June 2020

Im zweiten Teil der losen Reihe von begeisternden Einsendungen im Rahmen des Broschürenwettbewerbs (ausgelobt vom Netzwerk Patienten- und Familienedukation in der Pflege e. V.), möchten wir neben den ansprechenden Texten und Inhalten auf die Herausforderung des passenden Bildmaterials hinweisen. Die Broschüren der Lumia Stiftung haben hier mit einem künstlerischen, spielerischen Anspruch auf sehr ausdrucksstarke Zeichnungen zurückgegriffen, die unmittelbar ansprechen.
Praxisanleitung 2020 – nicht alles beim Alten!
Authors: Brand-Hörsting Birgit
Published: June 2020

Am 1. Januar 2020 ist das neue Pflegeberufegesetz in Kraft getreten. Auf dieser Grundlagewird die generalistische Ausbildung in den Pflegeschulen umgesetzt. Die Folgen für die Praxisanleitung sind weitreichend und fordern ein radikales Umdenken. Konkrete Beispiele zu den einzelnen Schritten des Anleitungsprozesses zeigen, wie die Umsetzung in der Kinderkrankenpflege aussehen kann.
Teilhabe eingeschränkt oder Zeit für neue Wege?
Authors: Janssen Christina
Published: June 2020

Wie geht es Ihnen? Durchleben Sie in diesen Zeiten auch verschiedene Phasen – von motiviert, überfordert bis hin zu dem Gedanken, wie es wohl weitergehen wird, wie sich das eigene Leben, die Umwelt und die Teilhabe verändern?
Sehnenscheide entlasten – Handtherapie bei Morbus de Quervain
Authors: Zumhasch Rainer
Published: June 2020

Eine Sehnenscheidenentzündung an der Hand entsteht meist durch einseitige Überbelastung. Handtherapie bietet mehrere Methoden, wie der Patient wieder zu Schmerzfreiheit gelangen kann.
Tätig sein mit Schmerzen – Kognitive Strategien zur Erweiterung der Handlungsfähigkeit
Authors: Amon Claudia
Published: June 2020

Psychosoziale Prozesse wie fortwährendes Ignorieren der eigenen Belastungsgrenze oder fehlende Selbstwirksamkeit tragen zur Chronifizierung von Schmerzen bei. An das PEO-Modell angelehnte kognitive Strategien können Klienten umfassend dabei unterstützen, bedeutungsvolle Betätigungen wieder durchzuführen.
Ressource für Klient und Therapeut – Coaching als Werkzeug in der Therapie
Authors: Hiebl Sara , Wiedemann Florian
Published: June 2020

Um Klienten aktiv in den Therapieprozess einzubinden, benötigen Ergotherapeuten entsprechendes Handwerkszeug. Erlernen sie die im CMCE geforderte Fähigkeit des Coachens, stärkt das sowohl die therapeutische Haltung als auch das berufliche Handeln.