bluuebunny/crossref_metadata_2025 huggingface dataset:
An Asp376Glu substitution in ALS gene and enhanced metabolism confers high tribenuron-methyl resistance in Sinapis alba
Authors: Palma-Bautista Candelario , Vázquez-García José G. , Osuna Maria D. , Garcia-Garcia Blanca , Torra Joel , Portugal Joao , De Prado Rafael
Published: November 2022

Acetolactate synthase (ALS) inhibiting herbicides (group 2) have been widely applied for the last 20 years to control Sinapis alba in cereal crops from southern Spain. In 2008, a tribenuron-methyl (TM) resistant (R) S. alba population was first reported in a cereal field in Malaga (southern Spain). In 2018, three suspected R S. alba populations (R1, R2 and R3) to TM were collected from three different fields in Granada (southern Spain, 100 km away from Malaga). The present work aims to confirm the putative resistance of these populations to TM and explore their resistance mechanisms. Dose–response assays showed that the R1, R2 and R3 populations ranging between 57.4, 44.4 and 57.1 times more resistance to TM than the susceptible population (S). A mutation in the ALS gene (Asp376Glu) was detected in the Rs S. alba populations. 14C-metabolism studies show that metabolites and TM were changing significantly faster in the R than in the S plants. Alternative chemical control trials showed that 2,4-D and MCPA (auxin mimics), glyphosate (enolpyruvyl shikimate phosphate synthase,EPSPS, inhibitor-group 9), metribuzin (PSII inhibitors/Serine 264 Binders, -group 5) and mesotrione (hydroxyphenyl pyruvate dioxygenase, HPPD, inhibitor-group 27) presented a high control of the four populations of S. alba tested, both S and R. Based on these results, it is the first case described where the Asp376Glu mutation and P450-mediated metabolism participates in resistance to TM in S. alba. Comparing these results with those found in the S. alba population in Malaga in 2008, where the resistance was TSR type (Pro197Ser), we can suggest that despite the geographical proximity (over 100 km), the resistance in these cases was due to different evolutionary events.
Biological nitrification inhibitor-trait enhances nitrogen uptake by suppressing nitrifier activity and improves ammonium assimilation in two elite wheat varieties
Authors: Bozal-Leorri Adrián , Subbarao Guntur V. , Kishii Masahiro , Urmeneta Leyre , Kommerell Víctor , Karwat Hannes , Braun Hans-Joachim , Aparicio-Tejo Pedro Mª , Ortiz-Monasterio Iván , González-Murua Carmen , González-Moro Mª Begoña
Published: November 2022

Synthetic nitrification inhibitors (SNI) and biological nitrification inhibitors (BNI) are promising tools to limit nitrogen (N) pollution derived from agriculture. Modern wheat cultivars lack sufficient capacity to exude BNIs, but, fortunately, the chromosome region (Lr#n-SA) controlling BNI production in Leymus racemosus, a wild relative of wheat, was introduced into two elite wheat cultivars, ROELFS and MUNAL. Using BNI-isogenic-lines could become a cost-effective, farmer-friendly, and globally scalable technology that incentivizes more sustainable and environmentally friendly agronomic practices. We studied how BNI-trait improves N-uptake, and N-use, both with ammonium and nitrate fertilization, analysing representative indicators of soil nitrification inhibition, and plant metabolism. Synthesizing BNI molecules did not mean a metabolic cost since Control and BNI-isogenic-lines from ROELFS and MUNAL presented similar agronomic performance and plant development. In the soil, ROELFS-BNI and MUNAL-BNI plants decreased ammonia-oxidizing bacteria (AOB) abundance by 60% and 45% respectively, delaying ammonium oxidation without reducing the total abundance of bacteria or archaea. Interestingly, BNI-trait presented a synergistic effect with SNIs since made it also possible to decrease the AOA abundance. ROELFS-BNI and MUNAL-BNI plants showed a reduced leaf nitrate reductase (NR) activity as a consequence of lower soil NO3− formation and a higher amino acid content compared to BNI-trait lacking lines, indicating that the transfer of Lr#-SA was able to induce a higher capacity to assimilate ammonium. Moreover, the impact of the BNI-trait in wheat cultivars was also noticeable for nitrate fertilization, with improved N absorption, and therefore, reducing soil nitrate content.
GmTOC1b inhibits nodulation by repressing GmNIN2a and GmENOD40-1 in soybean
Authors: Zhang Yuhang , Cheng Qun , Liao Chunmei , Li Lanxin , Gou Chuanjie , Chen Zheng , Wang Yanan , Liu Baohui , Kong Fanjiang , Chen Liyu
Published: November 2022

Symbiotic nitrogen fixation is an important factor affecting the yield and quality of leguminous crops. Nodulation is regulated by a complex network comprising several transcription factors. Here, we functionally characterized the role of a TOC1 family member, GmTOC1b, in soybean (Glycine max) nodulation. RT-qPCR assays showed that GmTOC1b is constitutively expressed in soybean. However, GmTOC1b was also highly expressed in nodules, and GmTOC1 localized to the cell nucleus, based on transient transformation in Nicotiana benthamiana leaves. Homozygous Gmtoc1b mutant plants exhibited increased root hair curling and produced more infection threads, resulting in more nodules and greater nodule fresh weight. By contrast, GmTOC1b overexpression inhibited nodulation. Furthermore, we also showed that GmTOC1b represses the expression of nodulation-related genes including GmNIN2a and GmENOD40-1 by binding to their promoters. We conclude that GmTOC1b functions as a transcriptional repressor to inhibit nodulation by repressing the expression of key nodulation-related genes including GmNIN2a, GmNIN2b, and GmENOD40-1 in soybean.
Presequence translocase-associated motor subunits of the mitochondrial protein import apparatus are dual-targeted to mitochondria and plastids
Authors: Gill-Hille Mabel , Wang Andre , Murcha Monika W.
Published: November 2022

The import and assembly of most of the mitochondrial proteome is regulated by protein translocases located within the mitochondrial membranes. The Presequence Translocase-Associated Motor (PAM) complex powers the translocation of proteins across the inner membrane and consists of Hsp70, the J-domain containing co-chaperones, Pam16 and Pam18, and their associated proteins Tim15 and Mge1. In Arabidopsis, multiple orthologues of Pam16, Pam18, Tim15 and Mge1 have been identified and a mitochondrial localization has been confirmed for most. As the localization of Pam18-1 has yet to be determined and a plastid localization has been observed for homologues of Tim15 and Mge1, we carried out a comprehensive targeting analysis of all PAM complex orthologues using multiplein vitroandin vivomethods. We found that, Pam16 was exclusively targeted to the mitochondria, but Pam18 orthologues could be targeted to both the mitochondria and plastids, as observed for the PAM complex interacting partner proteins Tim15 and Mge1.
Fostering openness in open science: An ethical discussion of risks and benefits
Authors: Khalil Ali Talha , Shinwari Zabta Khan , Islam Arshad
Published: November 2022

Transformation of science by embracing the concepts of open science presents a very attractive strategy to enhance the reliability of science. Open science policies embody the concepts of open data and open access that encompass sharing of resources, dissemination of ideas, and synergizing the collaborative forums of research. Despite the opportunities in openness, however, there are grave ethical concerns too, and they present a dual-use dilemma. Access to sensitive information is seen as a security risk, and it also possesses other concerns such as confidentiality, privacy, and affordability. There are arguments that open science can be harmful to marginalized groups. Through this study, we aim to discuss the opportunities of open science, as well as the ethical and security aspects, which require further deliberation before full-fledged acceptance in the science community.
Judging the emotional states of customer service staff in the workplace: A multimodal dataset analysis
Authors: Liu Ping , Zhang Yi , Xiong Ziyue , Wang Yijie , Qing Linbo
Published: November 2022

Background

Emotions play a decisive and central role in the workplace, especially in the service-oriented enterprises. Due to the highly participatory and interactive nature of the service process, employees’ emotions are usually highly volatile during the service delivery process, which can have a negative impact on business performance. Therefore, it is important to effectively judge the emotional states of customer service staff.

Methods

We collected data on real-life work situations of call center employees in a large company. Three consecutive studies were conducted: first, the emotional states of 29 customer service staff were videotaped by wide-angle cameras. In Study 1, we constructed scoring criteria and auxiliary tools of picture-type scales through a free association test. In Study 2, two groups of experts were invited to evaluate the emotional states of customer service staff. In Study 3, based on the results in Study 2 and a multimodal emotional recognition method, a multimodal dataset was constructed to explore how each modality conveys the emotions of customer service staff in workplace.

Results

Through the scoring by 2 groups of experts and 1 group of volunteers, we first developed a set of scoring criteria and picture-type scales with the combination of SAM scale for judging the emotional state of customer service staff. Then we constructed 99 (out of 297) sets of stable multimodal emotion datasets. Based on the comparison among the datasets, we found that voice conveys emotional valence in the workplace more significantly, and that facial expressions have more prominant connection with emotional arousal.

Conclusion

Theoretically, this study enriches the way in which emotion data is collected and can provide a basis for the subsequent development of multimodal emotional datasets. Practically, it can provide guidance for the effective judgment of employee emotions in the workplace.
Mood effects on semantic processes: Behavioural and electrophysiological evidence
Authors: Naranowicz Marcin
Published: November 2022

Mood (i.e., our current background affective state) often unobtrusively yet pervasively affects how we think and behave. Typically, theoretical frameworks position it as an embodied source of information (i.e., a biomarker), activating thinking patterns that tune our attention, perception, motivation, and exploration tendencies in a context-dependent manner. Growing behavioural and electrophysiological research has been exploring the mood–language interactions, employing numerous semantics-oriented experimental paradigms (e.g., manipulating semantic associations, congruity, relatedness, etc.) along with mood elicitation techniques (e.g., affectively evocative film clips, music, pictures, etc.). Available behavioural and electrophysiological evidence has suggested that positive and negative moods differently regulate the dynamics of language comprehension, mostly due to the activation of mood-dependent cognitive strategies. Namely, a positive mood has been argued to activate global and heuristics-based processing and a negative mood – local and detail-oriented processing during language comprehension. Future research on mood–language interactions could benefit greatly from (i) a theoretical framework for mood effects on semantic memory, (ii) measuring mood changes multi-dimensionally, (iii) addressing discrepancies in empirical findings, (iv) a replication-oriented approach, and (v) research practices counteracting publication biases.
“Save for a rainy day” or “live in the moment”? How does uncertainty associated with earthquakes affect people’s time preferences?
Authors: Ding Congming , Yan Xueying , Chen Zhiyuan
Published: November 2022

Uncertainty caused by frequent earthquakes can permanently reshape people’s time preferences, forcing them to confront the question of whether to “save for a rainy day” or “live in the moment.” Focusing on China, this study empirically analyzes the effect of earthquake frequency on local residents’ time preferences, using seismic data from 780 BCE to 1970 CE matched to the China Family Panel Studies (2010) database (CFPS). The results show that uncertainty arising from earthquakes continuously influences residents’ time preferences and behavior. Specifically, in regions with a higher earthquake frequency, residents’ saving rate is lower and households’ consumption level is higher, suggesting that people exposed to frequent earthquakes pay more attention to the present than the future. The results further show that residents’ education investment level and average education level are lower in higher earthquake frequency regions. The empirical evidence demonstrates that differences in mindset are the primary reason for the observed regional differences in consumption, savings and education. The results of a series of robustness tests demonstrate the robustness of the above-listed findings. This research sheds new light on the relationship between natural disasters and human time preferences.
The interplay between leaders’ personality traits and mentoring quality and their impact on mentees’ job satisfaction and job performance
Authors: Kumari Kalpina , Ali Salima Barkat , Batool Masooma , Cioca Lucian-Ionel , Abbas Jawad
Published: November 2022

This study focuses on examining the role of leaders’ Five-Factor Model (FFM) personality traits in their mentoring quality and mentees’ job satisfaction. It has also examined how leaders’ mentoring quality impacts mentees’ job satisfaction, leading to their job performance at the workplace. The study used an explanatory research methodology to determine the cause-and-effect relationship between mentors’ FFM personality characteristics, mentoring quality, and mentees’ job satisfaction and job performance. The study was based on path-goal theory and the Big Five-Factor Model of personality characteristics, and a questionnaire was utilized to collect information on the model’s constructs. Following the non-probability convenience sampling technique, the empirical data were collected from the academic and non-academic staff of public and private higher education institutions (HEIs) located within Pakistan on five-point Likert scale. The proposed hypotheses were tested by using PLS software. Four main conclusions were derived from this study. First, the leaders’ openness to new experiences, agreeableness, and emotional stability substantially influenced the mentees’ job satisfaction. Surprisingly, the leaders’ conscientiousness and extraversion qualities did not affect the job satisfaction of the mentees. Second, the findings demonstrated that the openness to experience, conscientiousness, and extroversion has a considerable influence on leaders’ mentoring quality, but agreeableness and emotional stability have a negligible impact. Third, the mentoring quality of the leader had a substantial effect on the job satisfaction and work performance of the mentees. Fourth, this study confirmed the belief that mentees’ job satisfaction has a favorable influence on their job performance within the context of Pakistan’s educational sector. The current study’s findings provided valuable insights to the educational institutions about which personality traits they need to foster in their leaders, making them an excellent leader to enhance their mentees’ job satisfaction and job performance within their organizational settings.
Eating attitudes and depressive symptoms in a LGBTIQ sample in Turkey
Authors: Gulec Hayriye , Torun Tayfun , Prado Aneliana da Silva , Bauer Stephanie , Rummel-Kluge Christine , Kohls Elisabeth
Published: November 2022

Background

Lesbian, gay, bisexual, transgender, intersexual and queer (LGBTIQ) individuals are often stigmatized due to their minority status. Sexual-minority stress is often discussed as a risk factor for the increased mental health problems reported in this population.

Objective

The current study (1) investigated eating attitudes and depressive symptoms in a sexual minority sample from Turkey who identify themselves as LGBTIQ and (2) explored the role of sexual minority stressors beyond the potential predictors of eating attitudes and depressive symptoms in this population.

Methods

Recruitment was supported and streamlined by several Turkish NGOs and LGBTIQ community networks. Sociodemographic measures, eating attitudes, depressive symptoms, sexual minority stressors (e.g., heterosexist experiences, internalized homophobia), and the potential predictors of eating attitudes and depressive symptoms were assessed with an anonymous online survey between February 2022 and June 2022. The sample consisted of 440 participants. The mean age was 31.92 (SD = 11.82). The majority of the participants reported their current gender identity as male (64.3%; n = 440) and their sexual orientation as attracted to men (62.8%; n = 439). For 79.7% of the participants, the assigned sex at birth was man (n = 439).

Results

Two separate three-stage multiple hierarchical regression analyses were conducted, controlling for sociodemographic characteristics and the risk and protective factors of eating attitudes and depressive symptoms. Disturbed eating attitudes were predicted by assigned female sex at birth, higher scores for depression, social isolation, and the total number of heterosexist experiences, and lower distress related to heterosexist experiences. Depressive symptoms were predicted by assigned female sex at birth, lesbian sexual orientation, disturbance in eating attitudes, increases in generalized anxiety, and distress related to daily heterosexist experiences.

Conclusion

The current study demonstrated the significant role of sexual minority stressors in the prediction of disturbed eating attitudes and depressive symptomatology beyond the general psychosocial vulnerability factors. These findings emphasize the need for developing strategies to reduce prejudicial attitudes at the societal level and to enhance the skills of LGBTIQ individuals in coping with sexual minority stressors in Turkey.
How to support adults with anorexia nervosa and autism: Qualitative study of clinical pathway case series
Authors: Li Zhuo , Hutchings-Hay Chloe , Byford Sarah , Tchanturia Kate
Published: November 2022

Introduction

Previous research has explored the overlapping presentation between autism and eating disorders (ED). This study aims to summarize the clinical challenges associated with co-occurring autism and anorexia nervosa (AN) based on clinicians' case notes and minutes from case discussions, to understand how to better support people with the comorbidity.

Method

Thematic analysis was conducted on de-identified notes on 20 cases with AN and autistic characteristics and minutes from case discussions. Themes relevant to clinical challenges in supporting those with the comorbidity were identified, and a thematic map was produced to visually represent the results.

Results

The key challenges faced by clinicians when treating patients with AN and autism included: communication difficulties, maintaining boundaries, autism screening, presence of other comorbidities, sensory difficulties, atypical presentation of eating difficulties, cognitive rigidity, and emotional difficulties. Adaptations to resolve some of these difficulties included exposure-based food experiments, keeping a record of patients' self-reported communication preferences, individual-level modification of communication style, and providing tools for patients to identify emotions.

Conclusions and implications

Further exploration to establish the effectiveness of the adaptations is warranted. Furthermore, tools for differentiating between ED, autism and other comorbidities are needed to help clinicians clarify the cause of a presenting symptom, and help them to best support and maintain boundaries with patients.
The multidimensional assessment of interoceptive awareness, version 2: Translation and psychometric properties of the Chinese version
Authors: Teng Binyu , Wang Dan , Su Conghui , Zhou Hui , Wang Tengfei , Mehling Wolf E. , Hu Yuzheng
Published: November 2022

Background

The Multidimensional Assessment of Interoceptive Awareness (MAIA) is a self-report questionnaire developed by Dr. Mehling that has been widely used to assess multiple dimensions of interoceptive awareness. To further improve the MAIA, Mehling developed the Multidimensional Assessment of Interoceptive Awareness, Version 2 (MAIA-2). The goal of this study is to systematically translate the MAIA-2 into Chinese and to investigate the psychometric properties of the Chinese version (MAIA-2C).

Materials and methods

The translation and adaptation of the questionnaire was conducted according to Beaton’s method. A total number of 627 participants were enrolled and completed the survey. The entire sample was randomly divided into a training sample (n = 300, 47.8%) and a validation sample (n = 327, 52.2%) for a cross-validation. Exploratory factor analysis (EFA) was used to identify the factor structure of the MAIA-2C in the training sample while confirmatory factor analysis (CFA) was used to test the factor structure obtained by EFA. The reliability of the MAIA-2C was indicated by Cronbach’s alpha. The convergent and discriminant validity were assessed by Pearson intercorrelations between the MAIA-2C and the Five-Facet Mindfulness Questionnaire (FFMQ) and State-Trait Anxiety Inventory-Trait anxiety (STAI-T).

Results

The EFA results showed an initial 10-factor model, but some items (1, 2, 3, 4, 15, and 16) were deleted because they did not yield the original subscale construct, eventually resulting in a 7-factor model. The CFA results represented a good model fit (χ2/df = 2.170, RMSEA = 0.060, SRMR = 0.0810, CFI = 0.890). The Cronbach’s alpha was 0.822 for the total scale and ranged from 0.656 to 0.838 for the subscales. The results of convergent and discriminant validity showed that most MAIA-2C subscales were correlated with the average score and subscales of FFMQ (r = −0.342∼0.535, p < 0.05), and all of the subscales of the MAIA-2C showed negative correlations with the STAI-T total score (r = −0.352∼−0.080, p < 0.05).

Conclusion

The MAIA-2C is a valid and reliable instrument for evaluating multiple dimensions of interoceptive awareness in a Chinese population.
The association between sedentary behavior and falls in older adults: A systematic review and meta-analysis
Authors: Jiang YueShuai , Wang Mei , Liu Shuang , Ya Xiao , Duan GuanTing , Wang ZiPu
Published: November 2022

Background

It is generally believed that sedentary behavior (SB) increases the risk of falls among older adults, but the evidence for it remains inconsistent and scarce.

Purpose

Our study aims to provide a systematic review and meta-analysis of available evidence regarding the association of SB with falls in older adults.

Method

A comprehensive search strategy was conducted using several online databases from 1906 to March 2022. Cohort studies both concerning the association between SB and falls and involving participants over 60 years old were regarded as eligible for inclusion. Evidence was pooled by a random-effects meta-analysis. Quality assessment for individual studies was performed with the Newcastle–Ottawa Scale (NOS).

Results

Altogether seven publications were identified, and the age of the 24,750 individuals involved ranging from 60 to 99 years old. Overall quality of the included studies was rated as moderate-to-high quality. We found that SB was significantly associated with increased risk of falls compared with non-SB among older adults [Odds ratio (OR) = 1.17, 95% confidence interval (CI): 1.07–1.28;I2= 46.90%,Pheterogeneity= 0.07, random model]. Subgroup analyses that stratified the studies according to NOS score showed significant differences between groups. Subgroup analysis stratified by SB measurement, sample size, region, publication year, and follow-up duration showed no significant differences between groups.

Conclusion

The findings provide reliable support for the hypothesis that sedentary lifestyles are strong predictors of falls among older adults, offering critical indications to develop strategies for fall prevention.
Psychological empowerment and job satisfaction in nurses: A systematic review and meta-analysis
Authors: Gu Lihua , Wang Liping , Pan Biwei
Published: November 2022

Background

Psychological empowerment is generally understood to be associated with job satisfaction among nurses. However, recently published literature has questioned this association.

Objective

We aimed to systematically investigate through a meta-analysis the association of psychological empowerment with job satisfaction among nurses.

Methods

PubMed, Medline, Cochrane Library, PsycInfo, and Embase were used to search targeted studies from conception to 20 January 2022. The correlation coefficients of each study were extracted and converted into Fisher's Z. Finally, pooled r was calculated by Fisher's Z and standard error (SE).

Results

A total of 28 studies encompassing 27 articles with 7,664 registered nurses were included. The pooled correlation coefficient between psychological empowerment and job satisfaction was 0.55. Subgroup analyses were conducted according to ethnicity, and the correlation in the Asian participants (P < 0.01) was significantly stronger (P < 0.05) than that of the Caucasian nurses (P < 0.01).

Conclusions

Psychological empowerment is strongly correlated to job satisfaction for registered nurses, especially among those from Asian countries. Interventions designed for psychological empowerment could be one of the strategies to promote the retention of nurses. Nonetheless, additional future studies are essential for more investigations.
Intrinsic limitations of nanofiltration membranes to achieve precise selectivity in water-based separations
Authors: Epsztein Razi
Published: November 2022

Over the last decades, nanofiltration (NF) membranes have been used to selectively remove certain solutes from water with recent interest targeting more challenging separations that require precise selectivity between solutes. In this perspective article, we aim to challenge (but not disprove) the prevalent notion that NF membranes are suitable for precise separations. We first provide and analyze selectivity data from the literature of three important separations including monovalent-divalent ion selectivity, separations involving organic molecules, and the more ambitious separations of ions with the same charge. We then introduce the terms rejection-based selectivity and transport-based selectivity to distinguish between the commonly “rough” separations pursued in NF (e.g., water softening) and the more visionary separations required for precise selectivity (e.g., transport of lithium through specific recognition sites), respectively. Using these terms, we discuss two major intrinsic limitations to achieve precise selectivity in NF systems; namely, the need for a solute-specific membrane that can transport simultaneously additional species (i.e., water and the complementary salt ion) and the detrimental effect of concentration polarization. We conclude with guidelines and principles to overcome these limitations.
Co-building trust in urban nature: Learning from participatory design and construction of Nature-Based Solutions in informal settlements in East Africa
Authors: Diep Loan , Mulligan Joe , Oloo Martha Akinyi , Guthmann Loė , Raido Mussa , Ndezi Tim
Published: November 2022

While the amount of research on NBS is growing rapidly, there is a lack of evidence on community experiences of NBS design and implementation, particularly from low-income and informal settlements of African cities. This article adds new empirical evidence in this space through grounded analysis of NBS “niche” projects co-developed by intermediary organizations and communities in five sites across three settlements in Nairobi and Dar es Salaam. Findings are organized around four established NBS knowledge gaps: (1) NBS-society relations; (2) Design; (3) Implementation; (4) Effectiveness. We find that across the five studied sites, residents' perceptions and valuation of urban nature has changed through processes of co-design and co-implementation, enabling community ownership of projects, and hence playing a crucial role in NBS effectiveness over time. The integration of gray components into green infrastructure to create hybrid systems has proven necessary to meet physical constraints and communities' urgent needs such as flood mitigation. However, maintenance responsibilities and cost burdens are persisting issues that highlight the complex reality of NBS development in informal settlements. The cases highlight key considerations for actors involved in NBS development to support the replication, scaling up and institutionalization of NBS. These include the need to: (i) develop forms of engagement that align with co-production values; (ii) capture communities' own valuation of and motivations with NBS development for integration into design; (iii) elaborate technical guidance for hybrid green-gray infrastructure systems that can be constructed with communities; and (iv) help define and establish structures for maintenance responsibilities (especially governmental vs. civil society) that will enhance the environmental stewardship of public spaces.
Case report of old anterior dislocation of the shoulder joint and review of the literature
Authors: Guo Weiming , Hui Ming , Yang Yuan , Wan Teng , Zeng Guang-Gui , Huang Peiguan , Wang Xiaoxu , Qiu Mingjun
Published: November 2022

Background

Dislocation of the shoulder joint is the most common type of joint dislocation. It is rare to be in a persistent dislocation that has not been reset. Successful arthroscopic treatment of the obsolete shoulder is relatively uncommon.

Case report

We report a rare case of persistent anterior dislocation of the old shoulder joint in a 30-year-old female patient. The patient underwent an emergency shoulder dislocation at a local hospital after a traumatic injury and re-dislocated persistently after surgery. 26 days later, she was admitted to our department for treatment, mainly because of joint deformity and limitation of motion. We adopted arthroscopic release and repositioning surgery. The patient was followed up for 1 year after surgery. Functional recovery was satisfactory.

Conclusion

The state of obsolete shoulder dislocation rarely occurs after shoulder dislocation and the prognosis of the patient is good after complete arthroscopic release and repositioning. It provides a reference for clinical arthroscopic treatment of old shoulder dislocations.
Homeostasis of the Intestinal Mucosa in Healthy Horses—Correlation between the Fecal Microbiome, Secretory Immunoglobulin A and Fecal Egg Count
Authors: Żak-Bochenek Agnieszka , Bajzert Joanna , Sambor Dominika , Siwińska Natalia , Szponar Bogumiła , Łaczmański Łukasz , Żebrowska Paulina , Czajkowska Aleksandra , Karczewski Maciej , Chełmońska-Soyta Anna
Published: November 2022

The defensive function of the intestinal mucosa depends both on the ability to secrete immunoglobulin A and communication with the mucus microbiome. In horses, the functioning of this system is also influenced by the presence of nematode eggs. Feces collected from healthy horses were examined to determine the fecal egg count, immunoglobulin A level (ELISA), microbiome composition (Next-Generation Sequencing, NGS, V3–V4 and V7–V9 hypervariable regions of the 16S rRNA gene analysis and short-chain fatty acid (SCFA) production ((high-performance liquid chromatography, HPLC). In the taxonomic analysis within the phylum, the following order of dominance was found: Firmicutes, Bacteroidota, Verrucomicrobiota and Fibrobacterota. The coefficient of phylogenetic diversity of the microbiome positively correlated with both secretory immunoglobulin A (SIgA) [μg/g of feces] (p = 0.0354, r = 0.61) and SIgA [μg/mg of fecal protein] (p = 0.0382, r = 0.6) and with the number of Cyathostomum eggs (p = 0.0023, r = 0.79). Important components of the key microbiome in horses, such as phylum Proteobacteria and species Ruminococcus flavefaciens, were positively correlated with the fecal SIgA (p < 0.05). All the obtained results indicate the existence of significant relationships between the host response (SIgA production) and composition and SCFA production in the microbiome as well as the presence of small strongyles in the digestive tract of horses.
Nicarbazin Residue in Tissues from Broilers Reared on Reused Litter Conditions
Authors: Feddern Vivian , Scheuermann Gerson N. , Coldebella Arlei , Gressler Vanessa , Bedendo Gizelle C. , Caron Luizinho , Pedroso Antonio C. , Bacila Danniele M. , Cunha Anildo
Published: November 2022

Nicarbazin (NCZ) is a worldwide used anticoccidial in poultry farming to avoid coccidiosis disease when chickens are reared on conventional poultry litter. If proper dosage and withdrawal time are not followed, the component dinitrocarbanilide (DNC) of NCZ may be present in chicken tissues, therefore posing a risk to consumers if the residues are above 200 µg/kg. Litter reuse is a common and important practice in commercial chicken production. Literature is lacking about the influence of litter reuse on DNC deposition in chicken tissues and its impact on food safety. We aimed to evaluate DNC residues in breast and liver by LC-MS/MS from broilers from an experiment with 10 consecutive flocks during 2 years. The experiment included three treatments containing NCZ in the diet (T1 = 125 mg/kg, 1–21 d; T2 = 125 mg/kg, 1–32 d; T3 = 40 mg/kg, 1–32 d). DNC residues in chicken breast at 21 d in T1 ranged from 648.8–926 µg/kg, at 32 d in T2 and T3 varied, respectively, from 232–667 µg/kg and 52–189 µg/kg. Regarding liver, DNC residues at 21 days in T1 ranged from 11,754–15,281 µg/kg, at 32 days in T2 and T3 varied, respectively, from 10,168–15,021 µg/kg and 2899–4573 µg/kg. When NCZ was withdrawn from feed, DNC residues dropped to <LOQ at 42 d in all treatments. Therefore, the reuse of poultry litter does not compromise food safety regarding DNC residues in chicken tissues, as shown herein up to 10 flocks.
Effects of Blasting Vibrations on an Arch in the Jiaohuayu Tunnel Described by Energy Response Spectrum Analysis
Authors: Hou Shijun , Xie Feng , Tian Shuaikang , Liang Shufeng
Published: November 2022

The vibrations caused by tunnel blasting strongly affects the construction safety and progress of the tunnel itself. The arch vibration attenuation law, structural energy response, and safety criterion were systematically investigated using blasting vibration monitoring in the Jiaohuayu Tunnel. The peak particle velocity (PPV) at the vault was always larger than that at the arch waist and was greater than that at the sidewall, regardless of the direction. The arch waist was where the initial lining had the highest risk of damage. Existing safety criteria can be supplemented and improved using the maximum instantaneous input energy to measure the first passage damage, the hysteretic energy consumption to measure the cumulative damage, and the input-hysteretic energy criterion to judge the structural failure. The energy threshold of the first passage damage of the initial lining structure was 200 J, and the plastic cumulative damage was 3000 J of the test section. This study is important when evaluating the safety of a tunnel’s initial lining structure.
Effects of Closed-Loop Devices on Omnidirectional Beam Patterns Radiated from WAVE Monopole Antennas
Authors: Kim Hong-Chan , Oh Sang-Jin , Park Chul-Soon
Published: November 2022

This study investigates the influence of closed-loop devices on omnidirectional beam patterns radiated from a Wireless Access for Vehicle Environment (WAVE) monopole antenna for facilitating communication stability in Vehicle-to-Vehicle and Vehicle-to-Everything technology. Single, dual, and quadruple closed-loop devices were introduced into the monopole antenna, and their surface current density and radiation beam patterns were analyzed by using the high-frequency structure simulator (HFSS) and computer simulation technology (CST) programs. As the closed-loop devices reflected the signal radiated from the antenna, the distribution of the surface current was concentrated around the monopole due to the creation of a closed-loop surface current path, which increased the gain value. The average gain was considerably increased by introducing closed-loop devices. The proposed antenna has an average gain of 1.57 dBi and a peak gain of 6.29 dBi at the operating frequency. Furthermore, omnidirectional beam patterns with a beam width of 359° were obtained by introducing four closed-loop devices into the monopole antenna, which eliminated nearly all null points in the frequency range of 5.85–5.925 GHz.
Streptomyces spp. Biofilmed Solid Inoculant Improves Microbial Survival and Plant-Growth Efficiency of Triticum aestivum
Authors: Domínguez-González Karla Gabriela , Robledo-Medrano J. Jesús , Valdez-Alarcón Juan José , Hernández-Cristobal Orlando , Martínez-Flores Héctor Eduardo , Cerna-Cortés Jorge Francisco , Garnica-Romo Ma. Guadalupe , Cortés-Martínez Raúl
Published: November 2022

Streptomyces species have been successfully used in diverse biotechnological processes; however, little is known about actinobacterial biofilm formation and its use as a biofilmed inoculant. The present study assessed and compared the ability of some plant growth-promoting actinobacterial strains to form biofilms on a carrier to improve microbial survival and colonize the rhizosphere and roots of Triticum aestivum, resulting in positive interactions and benefits to the plant. Forty-one actinobacterial isolates from Persea americana organic rhizosphere farms were tested on plant growth and biofilm-forming capacities, showing their potential use as bio-fertilizers in agriculture. Three Streptomyces strains were selected and tested for biofilm formation and plant growth-promoting (PGP) features. Biofilms were induced on the perlite carrier and used to inoculate seven treatments with T. aestivum in pot essays, resulting in a >200% increase in root weight and a >400% increase in total biomass. Endophytic colonization was achieved in all the treatments. Microbial survival ranged between 108 and 109 CFU/g after 12 weeks of treatment, indicating actinobacterial permanence on the carrier. Successful consortia formation was observed for mixed-strain treatments, suggesting long-term plant recolonization.
Bioinformatics Predicted Linear Epitopes of the Major Coat Protein of the Beet Yellows Virus for Detection of the Virus in the Cell Extract of the Infected Plant
Authors: Skurat Eugene V. , Butenko Konstantin O. , Drygin Yuri F.
Published: November 2022

Beet yellows virus, which belongs to the genus Closterovirus, family Closteroviridae and has a significant negative economic impact, has proven to be challenging to detect and diagnose. To obtain antibodies against BYV, we propose an easier bioinformatics approach than the isolation and purification of the wild virus as an antigen. We used the SWISS-MODEL Workspace (Biozentrum Basel) protein 3D prediction program to discover epitopes of major coat protein p22 lying on the surface of the BYV capsid. Sequences coding these epitopes were cloned into plasmid pQE-40 (Qiagen) in frame with mouse dihydrofolate reductase gene. Fused epitopes were expressed in Escherichia coli and isolated by the Ni-NTA affinity chromatography. Murine antibodies were raised against each epitope and in a combination of both and characterized by dot-ELISA and indirect ELISA. We successively used these antibodies for diagnosis of virus disease in systemically infected Tetragonia tetragonioides. We believe the approach described above can be used for diagnostics of difficult-to-obtain and hazardous-to-health viral infections.
Experimental Study of Frame-Supported Shear Wall Structure of High-Rise Buildings with Transfer Slab in Metro Depot
Authors: Xia Yishu , Li Wuxiong , Liu Weiya , Liu Yanhui , Xu Xin , Zhang Chenyun
Published: November 2022

Taking the frame-supported shear wall structure of a 102.1 m high metro depot as the test object, the structure has obvious vertical irregularity, and a quasi-static test was carried out on the structural model with the scale of 1/5. The damage development and strain of the structure were observed by applying displacement loads under different seismic actions, and the experimental phenomena and measured data were analyzed. The results show that the safety performance of the structure meets the seismic requirements of the MCE (Maximum considered earthquake) condition. Under the action of load, a reasonable damage mechanism is formed in which the components above the transfer story crack first and those below the transfer story crack later, which is in line with the design concept of “the performance objective of the bottom frame structure is higher than that of the upper shear wall structure”. The transfer plate is mainly subjected to shear deformation, the possible shear failure of the transfer plate should be avoided by reasonable design. Due to the large height difference between the first floor and the second floor, the structure may be adversely affected, so it is necessary to make the yielding floor appear in the bottom strengthening part above the transfer story. Under the SLE (Service level earthquake) and DBE (Design based earthquake) conditions, the bottom frame of the structure is mainly subjected to elastic deformation. Under the MCE (Maximum considered earthquake) condition, the bottom frame of the structure causes a lot of damage, increases energy consumption and decreases stiffness, which further proves that “the performance goal of the bottom frame structure is higher than that of the upper shear wall structure”.
Metaverse as Future Promising Platform Business Model: Case Study on Fashion Value Chain
Authors: Periyasami Saravanan , Periyasamy Aravin Prince
Published: November 2022

The concept of a ‘business model’ refers to a collection of descriptions that highlight the most significant aspects of the business. The metaverse is already a reality that can be considered plausible; it is a digital world that can be accessed by various technologies, such as virtual or augmented reality, and it is a place in which people are able to communicate and collaborate with one another. Businesses are making an attempt to capitalize on a trend, since it is anticipated that the metaverse will become more decentralized in the near future because it provides outstanding possibilities for expanding business. In this article, we discuss a few aspects of the current business model, as well as the emergence of the metaverse and their influence in the existing business models, with emphasis on the fashion and retail industry. Users of the metaverse have the ability to personalize digital representations of themselves, known as avatars. These avatars may be utilized in virtual worlds, online games, and other types of online communities. The way advertising works in the metaverse is quite similar to how it operates in the real world. Because of this, there is a promising future in store for the future of marketing and advertising in the metaverse. The new virtual environment will inspire us to devise novel formulae and procedures, which will influence the user in previously unimaginable ways. In addition to that, the possibility of the metaverse becoming connected with generation Z (also known as gen Z) would be additional advantages that will help the company’s bottom line in the decades to come.
Lenvatinib as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Authors: Wang Shijie , Wang Yiting , Yu Jiangtao , Wu Huaxing , Zhou Yanming
Published: November 2022

Lenvatinib was approved in 2018 as a first-line treatment for patients with unresectable hepatocellular carcinoma (HCC). This systematic review and meta-analysis aimed to provide the most updated evidence about the efficacy and safety of lenvatinib as a first-line treatment for unresectable HCC. An electronic search of the PubMed database, Web of Science, Embase, and Cochrane Library was undertaken to identify all relevant studies up to May 2022. The pooled effect sizes were calculated based on the random-effects model. One phase III randomized controlled trial and 23 retrospective studies of 2438 patients were eligible for analysis. For patients treated with lenvatinib as first-line treatment, the pooled median overall survival (OS), median progression-free survival (PFS), 1-year OS rate, 1-year PFS rate, objective response rate (ORR), and disease control rate (DCR) were 11.36 months, 6.68 months, 56.0%, 27.0%, 36.0% and 75.0%, respectively. Lenvatinib showed a significantly superior efficacy compared with sorafenib (HR for OS, 0.85 and HR for PFS, 0.72; OR for ORR, 4.25 and OR for DCR, 2.23). The current study demonstrates that lenvatinib can provide better tumor responses and survival benefits than sorafenib as a first-line treatment for unresectable HCC, with a comparable incidence of adverse events.
Simultaneous Onset of Haematological Malignancy and COVID: An Epicovideha Survey
Authors: Cattaneo Chiara , Salmanton-García Jon , Marchesi Francesco , El-Ashwah Shaimaa , Itri Federico , Weinbergerová Barbora , Gomes Da Silva Maria , Dargenio Michelina , Dávila-Valls Julio , Martín-Pérez Sonia , Farina Francesca , Van Doesum Jaap , Valković Toni , Besson Caroline , Poulsen Christian Bjørn , López-García Alberto , Žák Pavel , Schönlein Martin , Piukovics Klára , Jaksic Ozren , Cabirta Alba , Ali Natasha , Sili Uluhan , Fracchiolla Nicola , Dragonetti Giulia , Adžić-Vukičević Tatjana , Marchetti Monia , Machado Marina , Glenthøj Andreas , Finizio Olimpia , Demirkan Fatih , Blennow Ola , Tisi Maria Chiara , Omrani Ali S. , Navrátil Milan , Ráčil Zdeněk , Novák Jan , Magliano Gabriele , Jiménez Moraima , Garcia-Vidal Carolina , Erben Nurettin , Del Principe Maria Ilaria , Buquicchio Caterina , Bergantim Rui , Batinić Josip , Al-Khabori Murtadha , Verga Luisa , Szotkowski Tomáš , Samarkos Michail , Ormazabal-Vélez Irati , Meers Stef , Maertens Johan , Pinczés László Imre , Hoenigl Martin , Drgoňa Ľuboš , Cuccaro Annarosa , Bilgin Yavuz M. , Aujayeb Avinash , Rahimli Laman , Gräfe Stefanie , Sciumè Mariarita , Mladenović Miloš , Çolak Gökçe Melis , Sacchi Maria Vittoria , Nordlander Anna , Berg Venemyr Caroline , Hanáková Michaela , García-Poutón Nicole , Emarah Ziad , Zambrotta Giovanni Paolo Maria , Nunes Rodrigues Raquel , Cordoba Raul , Méndez Gustavo-Adolfo , Biernat Monika M. , Cornely Oliver A. , Pagano Livio
Published: November 2022

Background: The outcome of patients with simultaneous diagnosis of haematological malignancies (HM) and COVID-19 is unknown and there are no specific treatment guidelines. Methods: We describe the clinical features and outcome of a cohort of 450 patients with simultaneous diagnosis of HM and COVID-19 registered in the EPICOVIDEHA registry between March 2020 to February 2022. Results: Acute leukaemia and lymphoma were the most frequent HM (35.8% and 35.1%, respectively). Overall, 343 (76.2%) patients received treatment for HM, which was delayed for longer than one month since diagnosis in 57 (16.6%). An overall response rate was observed in 140 (40.8%) patients after the first line of treatment. After a median follow-up of 35 days, overall mortality was 177/450 (39.3%); 30-day mortality was significantly higher in patients not receiving HM treatment (42.1%) than in those receiving treatment (27.4%, p = 0.004), either before and/or after COVID-19, or compared to patients receiving HM treatment at least after COVID-19 (15.2%, p < 0.001). Age, severe/critical COVID-19, ≥2 comorbidities, and lack of HM treatment were independent risk factors for mortality, whereas a lymphocyte count >500/mcl at COVID-19 onset was protective. Conclusions: HM treatment should be delivered as soon as possible for patients with simultaneous diagnosis of COVID-19 and HM requiring immediate therapy.