bluuebunny/crossref_metadata_2025 huggingface dataset:
Sixth-generation seismic hazard model of Canada: grid values of mean hazard to be used with the 2020 National Building Code of Canada
Authors: Kolaj M , Halchuk S , Adams J
Published: March 2023

Canada's 6th Generation seismic hazard model is the basis for the seismic design provisions in the 2020 National Building Code of Canada. The 2020 code uses mean ground motions of spectral acceleration at 0.2, 0.5, 1.0, 2.0, 5.0 and 10.0 second periods, peak
acceleration and peak velocity for a variety of site conditions. Users of the 2020 code access seismic hazard values by using the 2020 National Building Code of Canada Seismic Hazard Tool which provides values for any site located in Canada. The online tool accomplishes this through the
interpolation of a pre-calculated dataset. This Open File provides that dataset for users who may wish to access those values directly, and describes the interpolation methods used.
The monostotic fibrous dysplasia with extensive lesions in the humerus: A report of two cases and review of the literature
Authors: Guo Yu , Feng Dehong , Wang Ling , Ding Yujian , Liu Yi , He Junshan , Zhao Jijun , Gu Xiaofeng
Published: March 2023

Fibrous dysplasia (FD) is a common benign skeletal disease. In this report, we retrospectively analyzed two cases of monostotic FD with extensive lesions involving the middle and proximal humerus with fractures, where a thorough curettage and autograft followed by interfixation were performed. However, one patient was cured successfully, and the other one had repeated recurrences and pathological fractures. Finally, with the help of computer-aided design and three-dimensional printing technology, the other one patient was cured by unconstrained reverse shoulder arthroplasty combined with allograft-prosthetic composite technology.
Knowledge and practice of eye drops instillation technique in India: A survey of 396 optometrists
Authors: Chaurasiya Ritesh K , Gupta Akansha , Goswami Sarbojeet
Published: March 2023

Aim:

The aim of this article is to evaluate the knowledge about perfect eye drops instillation technique among optometrists in India.

Materials and Methods:

An online questionnaire-based, cross-sectional study was conducted. A self-administered, electronic questionnaire with a cover letter explaining the aim of the study was distributed among optometrists practicing in India. Demographic characteristics were summarized using descriptive statistics. Categorical variables were summarized using frequencies and percentages.

Results:

Among 396 respondents, 237 (59.84%) were females and 159 (40.16%) were males with a mean age of 24.5 ± 2.81 years. Two-fifths of the optometrists opted for washing hands before eye drop instillation. Similarly, almost nine-tenths of the participants preferred to instill eye drops asking patients to sit and about one-tenth of the optometrist preferred patients in supine position during administering drops. Most common errors during drop instillation among optometrists were drop instillation without nasolacrimal occlusion (19.95%) and hand hygiene (69.94%).

Conclusion:

Proper education and awareness about eye drop instillation process should be given to all eye care practitioners so that non-compliance and incorrect methods of drop instillation can either be minimized or nullified from patients’ end.
Large consecutive esotropia after uneventful surgical correction of infantile exotropia: A post-operative surprise
Authors: Rani Nisha , Singh Anupam , Chand Stuti , Verma Shreya , Khurana Mittali , Mittal Sanjeev K
Published: March 2023

Abstract

The incidence of consecutive esotropia developing after exotropia surgery has been reported to be 6%–20%. Consecutive esotropia with limited abduction requires reoperation on the muscles that were operated during the first surgery. It is difficult to predict the result of the second surgery because it may convert to exodeviation after the advancement of lateral rectus (LR) muscle, the contracture of the previously recessed muscle, or hypertrophy of resected medial rectus (MR). We present a case of 20-year-old woman with infantile exotropia who underwent bilateral lateral rectus recession and left MR resection in view of a large primary position deviation of 55 prism diopter (PD) at a 6-meter distance. But the patient developed large consecutive esotropia of 50 PD within 3 weeks of surgery with abduction limitation in the left eye, which was highly suspicious of slippage of the left LR. But when the LR was explored, it was found at 16 mm from the limbus without any evidence of slippage. In view of the abnormal response after the first surgery, the LR was advanced by 9 mm, and was inserted at 7 mm from limbus. The patient was orthophoric on the first postoperative day, and the alignment was maintained till 6 months of follow-up. This case is unique in terms of unexpected large consecutive esotropia of 50 PD after uncomplicated routine strabismus surgery, which was corrected by advancement of one LR only. This event could be possibly due to lack of binocularity and fusion in these patients with an associated component of dissociated horizontal deviation. This report emphasizes the possibility of some unusual postoperative outcomes in spite of careful and meticulous preoperative workup, and uneventful squint surgery in patients with infantile deviation.
Factors Associated with Neonatal Survival in a Special Care Newborn Unit in a Tertiary Care Hospital in Bangladesh
Authors: Kumar Ananya A. , Lee Kyu Han , Pervez Abu Faisal Md , Bari Sanwarul , Deb Chayon , Arifeen Shams El , Islam Farzana , Gurley Emily S.
Published: March 2023

The 2020 neonatal mortality rate in Bangladesh was 17 deaths per 1,000 live births, higher than the 2030 Sustainable Development Goal target (12 deaths per 1,000 live births). Over the past decade, Bangladesh has established special care newborn units (SCANUs) in medical facilities countrywide to improve neonatal survival. We conducted a retrospective cohort study in the SCANU of a tertiary-level healthcare facility in Bangladesh to study neonatal survival and associated risk factors using descriptive statistics and logistic regression models. Of 674 neonates admitted to the unit between January and November 2018, 263 (39%) died in hospital, 309 (46%) were discharged against medical advice, 90 (13%) were discharged healthy, and 12 (2%) had other discharge statuses. The median duration of time spent in hospital was 3 days, and 60% were admitted at birth. Neonates delivered via Cesarean section (adjusted odds ratio [aOR]: 2.5; 95% CI: 1.2–5.6) had an increased odds of recovering and being discharged, whereas those diagnosed with prematurity and/or low birth weight at admission (aOR: 0.2; 95% CI: 0.1–0.4) had a decreased odds of doing so. The high mortality rate and large number of neonates discharged against medical advice suggest a need to investigate the etiology of death and the factors leading to children leaving hospital prior to recovery. Medical records lacked information on gestational age that could provide key insights about mortality risk and age of viability in this setting. Addressing these knowledge gaps in SCANUs may enable better support for the improvement of child survival.
Current Helicobacter pylori Infection Is Associated with Early Liver Injury: A Cross-Sectional Study in the General Population
Authors: Chang Wenling , Cai Lin , Chen Tingting , Ni Weigui , Xie Zhihao , Yang Chunxia , Liao Juan
Published: March 2023

Early prevention of liver injury by controlling risk factors deserves concern because of the heavy liver disease burden. Helicobacter pylori (HP) infection affects half of the world’s population and the relationship between it and early liver damage is unclear. This study focuses on assessing the correlation between them in the general population to provide clues to prevent liver disease. A total of 12,931 individuals underwent liver function and imaging tests as well as 13C/14C-urea breath tests. Results showed that the detection rate of HP was 35.9%, and the HP-positive group had a higher rate of liver injury (47.0% versus 44.5%, P = 0.007). Specifically, Fibrosis-4 (FIB-4) and alpha-fetoprotein levels in the HP-positive group were higher whereas the serum albumin level was lower. HP infection would raise the percentage of elevated aspartate aminotransferase (AST; 2.5% versus 1.7%, P = 0.006), elevated FIB-4 (20.2% versus 17.9%, P = 0.002), and abnormal liver imaging (31.0% versus 29.3%, P = 0.048). Most of these results remained stable after covariate adjustment but, for liver injury and liver imaging, the conclusions only held in young people (ORliver injury, odds ratio of liver injury, 1.127, P = 0.040; ORAST, 1.33, P = 0.034; ORFIB-4, 1.145, P = 0.032; ORimaging, 1.149, P = 0.043). Overall, HP infection might be associated with early liver injury, particularly in youth, suggesting that people with early liver injury should pay more attention to HP infection to prevent the occurrence of severe liver diseases.
Malaria Paradoxes of the U.S. Civil War
Authors: Shanks G. Dennis
Published: March 2023

The U.S. Civil War (1861–1865) pre-dated modern understanding of malaria. Yet, malarial diseases (remittent fever, intermittent fever, typho-malarial fever) were frequently reported as causes of morbidity and mortality in soldiers. Modern readers find Civil War-era descriptions of malaria contradictory or paradoxical. For example, although the concept of race-specific immunity to tropical diseases was widely accepted, malaria mortality rates were reportedly more than three times higher among Black than White Union soldiers (16/1,000/year versus 5/1,000/year). Also, malaria rates were reportedly lower among prisoners of war at the infamous Andersonville, GA, prison camp than among Confederate soldiers in the same area. Literally tons of quinine were given prophylactically to Union soldiers deployed in the southern United States, but blackwater fever was not reported by medical officers. All three paradoxes have reasonable modern explanations that give credence to the astute clinical observations of our scientific predecessors during the U.S. Civil War.
In Silico Analysis of 14-Deoxy 11, 12-Didehydro Andrographolide (AGP 2) from Sambiloto (Andrographis paniculata) as Drug Candidate Against SARS-CoV-2
Authors: Astria Muhammad Vicky , Waluyo Lud , Latifa Roimil , Nuryadi Moh. Mirza , Susetyarini Rr. Eko , Labo Mohd. Affendi
Published: March 2023

The outbreak of the COVID-19 pandemic in the world has urged researchers to develop a vaccine or therapeutic drugs to fight this virus. This study aimed to assay 14 deoxy-11,12-didehydroandrographolide (AGP 2) ability as an inhibitor of 3-chymotrypsin like-protease (3CLPro), Papain-like protease (PLPro), and RNA-dependent RNA-polymerase (RdRp), the viral proteins of SARS-CoV-2 and to evaluate it safeness as a drug candidate. In-silico technique was performed in this study to analyze the binding interaction, complex stability between protein and ligand, and drug-likeness properties. The proteins and ligands were obtained from Protein Data Bank (PDB) and PubChem web tools, then using PyRx to identify the binding affinity score, PyMoL to visualize the 3D binding interaction, and WebGro web tools to analyze the stability of each complex. A drug-likeness evaluation was done using SwissADME, pkCSM, and Way2drug web tools. The result of this study showed that the binding affinity score for each complex is; AGP 2-3CLPro (-6.7 kcal/mol), AGP 2- PLPro (-6.4 kcal/mol), and AGP 2-RdRp (-7.0 kcal/mol) where the AGP 2-RdRp and AGP 2-3CLPro showed a stable form indicating the inhibitor ability of AGP 2. This study also demonstrates that the drug-likeness properties of AGP 2 are safe to use. Additionally, it has been proved that AGP 2 can be developed into a therapeutic drug with further studies.
New MPPT Hybrid Controller based on Genetic Algorithms and Particle Swarm Optimization for Photovoltaic Systems
Authors: Mammeri E. , Ahriche A. , Necaibia A. , Bouraiou A.
Published: March 2023

Traditional Maximum Power Point Tracking (MPPT) techniques are unable to reach high performance in photovoltaic (PV) system under partial shading conditions because of the multi-peaks present in the Power-Voltage curve. For that, particle Swarm Optimization (PSO) and genetic algorithms (GA) have been combined in recent years. However, these algorithms demonstrate some drawbacks in tracking accuracy and convergence rates, which impair control performance. In this paper, a new controller based on hybridization of PSO and GA is introduced to track the global maximum power point (GMPP). The proposed algorithm (HPGA) increases the balance rate between exploration and exploitation due to the cascade design of GA and PSO. Thus, the GMPP tracking of both algorithms will be improved. Simulations are carried out based on ISOFOTON-75W PV modules to prove the high performance of the proposed algorithm. From the obtained results, we conclude that HPGA shows fast convergence and very good tracking accuracy of GMPP in PV system even under different shading patterns.
Spectral Efficiency Performance of Multi Cell MIMO Systems in Impulsive Noise Channels
Authors: Hilal H. Abu
Published: March 2023

This research report details how impulsive noise affects communication systems. This research evaluates the differences and similarities among impulse models in communication systems. After comparing and contrasting the impulse noise models' similarities and differences, the models' service execution will be compared. Spectral efficiency is the fundamental criterion for comparing models' service execution. Comparing models under different impulse noise levels and inter- cell and intra-cell intercession will also be done. The 5G mm Wave multiple input/output system's service execution will be researched. The study will use IN. First, the Gaussian noise scenario will be deduced for the stated device's performance, followed by the non- Gaussian noise scenario derivation. The latter deriva- tion also involves averaging Gaussian noise in terms of impulsive noise's spread. Monte Carlo simulations are used to show and support derivations.
Improving the Accuracy for Amplitude and Frequency of Analytical Equation of Single-ended Ring Oscillators Based on Circuit and Transistor Parameters
Authors: Moradnezhad Mehrdad , Miar-Naimi Hossein
Published: March 2023

The analytical relationships presented for amplitude and frequency of the ring oscillator are derived approximately due to the nonlinear nature of this oscillator. In the case where the transistors experience the cut-off region, the relationships presented so far have no connection between the frequency and the dimensions of the transistor, which is not valid in practice. In this paper, considering the circuit’s governing equation and the ring oscillator’s output waveform, a relation for the frequency is presented, including the dimensions of the transistor. Also, a simple and approximately accurate relationship for the oscillator amplitude is provided in this case. The validity of these relationships has been investigated by analyzing and simulating a single-ended oscillator in 0.18μm technology.
Utilization of Waste Glass for Enhancement of Chemical Properties of Concrete
Authors: Gupta Jagriti , Jethoo A. S. , Lata Nandeshwar
Published: March 2023

The world is facing a huge problem of waste generation; among these, solid waste in the form of glass has become a prime concern for the environment. The composition of the glass is silica-based, and its utilization in the preparation of concrete can be an efficient step in the direction of sustainable development by reducing the cement content. The formation of secondary calcium silicate hydrates (C-S-H) could take place due to the pozzolanic reaction of the fine ground glass with the cement. TGA techniques were used in this research to investigate the chemical properties of the waste glass, and later, these were compared with the properties of the cement. By keeping a constant w/b ratio for all the replacement levels from 0% to 35%, the evaluation of the workability and compressive strength were done. The evaluation showed that workability increased with an increase in the content of the waste glass. With 7 and 28 days cured samples, the strength and chemical investigation were conducted on the samples prepared with the same mix design. Constant Dose of superplasticizer used by weight of cement for mixes as 0.8%. Compared with the control sample, The level of replacement of waste glass to cement as 30% has depicted the augmentation in the compressive strength. Thus, the use of waste glass was found to be cost-effective and an environment-friendly solution for the sustainable development of concrete.
Analysis of Water Quality of Hatirjheel Lake, Dhaka, Bangladesh
Authors: Pasha A. B. M. Kamal , Mustafa Syed Omayer , Rahman S. M. Mahmudur , Abdullah Muhammad , Chowdhury Md. Azharul Haque , Parveen Mahfuza
Published: March 2023

The study assessed the status of water quality parameters for an urban water body (Hatirjheel Lake) in Dhaka, the Capital city of Bangladesh. Nine different water samples were collected from nine points of the lake during the dry season in January 2021. Water quality parameters such as pH, electrical conductivity (EC), total dissolved solids (TDS), total suspended solids (TSS), total alkalinity, total acidity, total hardness, Ca2+ hardness, free CO2, and dissolved oxygen (DO) were determined for the samples. The status of the parameters is pH (6.51-7.05), EC (510-600 μS.cm-1), TDS (450-590 ppm), TSS (0.0-0.034 mg.L-1), total alkalinity (80-392 mg.L-1), total acidity (224-500 mg.L-1), total hardness (348-452 mg.L-1), Ca2+ hardness (74-162 mg.L-1), free CO2 (730-1170 mg.L-1), DO (2.7-5.5 mg.L-1). However, the DO value at some points of the lake is too less (2.7 mg.L-1 and 3.7 mg.L-1) than the standard value (> 5-6 mg.L-1) of ECR, DoE, which might not be healthy for any water body and aquatic ecosystem. Other water quality parameters are within the permissible limit of WHO and ECR, DoE.
Turbidity Reduction and Eco-friendly Sludge Disposal in Water Treatment Plants
Authors: Sinsinwar Roop Singh , Verma Munna
Published: March 2023

Plankton and other microscopic colloids are tiny particles that are suspended in water and cause turbidity, which causes the water to seem murky or opaque. These particles are too unstable and light to settle or be naturally eliminated. These details contribute to water turbidity and pose some stability. During the process of purifying raw water, all water treatment Plants (WTPs) produce waste/residue known as water treatment sludge (WTS). The majority of the sludge’s chemical components include silica, alumina, ferric oxide, lime, and many heavy metals. The surface water treatment technique included coagulation, flocculation, sedimentation, and filtration to remove colloidal and suspended particles from raw water. The sludge obtained from the WTP located at Kekri (Rajasthan), India is being investigated for its physical and chemical properties. About 60% of the sand contained in the sludge is found in the 155-60 grain size range. Additionally, nutrient reduction of soil due to contamination and runoff can be minimized or rounded out by wastewater treatment or the removal of heavy metals from water solutions. To develop water-safe and appealing sludge management solutions, the efficiency of aluminum sulfate and poly aluminum chloride was assessed at different coagulant doses in the study. To make water safe and appealing for human consumption, numerous purification procedures are employed from a variety of sources. Sludge bricks are acceptable to high temperatures in the furnace and have better compressive strength than clay bricks.
Study of Some Stability Parameters in the Atmosphere of Oil Al-Dura Refinery, Southeast Baghdad
Authors: Lagenean Farant H. S. , Naif Salwa S. , Al-Jiboori Monim H.
Published: March 2023

Wind and temperature measurements at an oil refinery site located southeast of Baghdad city at two levels, 15 and 30 m, are presented. Three schemes are used to determine different stability classifications: Monin-Obukhov length, gradient, and bulk Richardson numbers. Meanwhile, vertical changes in air temperature and wind shear are also computed. There were lapse rate and inversion cases during the nights and days while favorable wind shear was dominant. The variation of stability in each scheme is large, covering the entire range of stability for a given class. The results of stability schemes are compared to each other. The results show that the schemes based on gradient and bulk Richardson numbers reasonably compare them.
Feasibility of Waste-to-Energy Plants for STT-PLN Campus Canteen
Authors: . Pawenary , Larasati Amelia Dwita , . Suhdi , Wardhani Rulyanti Susi
Published: March 2023

The pellets of waste produced by Society Electric [Listrik Kerakyatan (LK) 2] at the STT-PLN have not been efficiently utilized in terms of energy. The STT-PLN canteen consists of 14 stalls with an installed electricity capacity of 1300 VA, each with 12h of use/day. This study aimed to convert LK 2 waste pellets into electrical energy to supply electricity to the STT-PLN canteen. This research method uses quantitative methods, i.e., by calculating the amount of energy produced adjusted to the needs of the canteen. Gasification technology was chosen due to its high efficiency and lower emission impacts in the waste combustion technique. Based on the analysis, the gasifier engine that complies with this requirement was TG30-1 with a maximum capacity of 25 kVA and requires a flow rate of 10 kg.h-1 of waste pellets. The amount of waste pellets used for this plan was 120 kg.day-1. The assessment results of this plan indicated a net present value of IDR 302,218,609.33, an internal rate of return of 25.7983%, and a PBP of 5.66 years. Based on the economic analysis, the establishment of plants for the conversion of waste to power was declared feasible to operate.
Efficient Private Circuits with Precomputation
Authors: Wang Weijia , Ji Fanjie , Zhang Juelin , Yu Yu
Published: March 2023

At CHES 2022, Wang et al. described a new paradigm for masked implementations using private circuits, where most intermediates can be precomputed before the input shares are accessed, significantly accelerating the online execution of masked functions. However, the masking scheme they proposed mainly featured (and was designed for) the cost amortization, leaving its (limited) suitability in the above precomputation-based paradigm just as a bonus. This paper aims to provide an efficient, reliable, easy-to-use, and precomputation-compatible masking scheme. We propose a new masked multiplication over the finite field Fq suitable for the precomputation, and prove its security in the composable notion called Probing-Isolating Non-Inference (PINI). Particularly, the operations (e.g., AND and XOR) in the binary field can be achieved by assigning q = 2, allowing the bitsliced implementation that has been shown to be quite efficient for the software implementations. The new masking scheme is applied to leverage the masking of AES and SKINNY block ciphers on ARM Cortex M architecture. The performance results show that the new scheme contributes to a significant speed-up compared with the state-of-the-art implementations. For SKINNY with block size 64, the speed and RAM requirement can be significantly improved (saving around 45% cycles in the online-computation and 60% RAM space for precomputed values) from AES-128, thanks to its smaller number of AND gates. Besides the security proof by hand, we provide formal verifications for the multiplication and T-test evaluations for the masked implementations of AES and SKINNY. Because of the structure of the new masked multiplication, our formal verification can be performed for security orders up to 16.
Conditional Variational AutoEncoder based on Stochastic Attacks
Authors: Zaid Gabriel , Bossuet Lilian , Carbone Mathieu , Habrard Amaury , Venelli Alexandre
Published: March 2023

Over the recent years, the cryptanalysis community leveraged the potential of research on Deep Learning to enhance attacks. In particular, several studies have recently highlighted the benefits of Deep Learning based Side-Channel Attacks (DLSCA) to target real-world cryptographic implementations. While this new research area on applied cryptography provides impressive result to recover a secret key even when countermeasures are implemented (e.g. desynchronization, masking schemes), the lack of theoretical results make the construction of appropriate and powerful models a notoriously hard problem. This can be problematic during an evaluation process where a security bound is required. In this work, we propose the first solution that bridges DL and SCA in order to get this security bound. Based on theoretical results, we develop the first Machine Learning generative model, called Conditional Variational AutoEncoder based on Stochastic Attacks (cVAE-SA), designed from the well-known Stochastic Attacks, that have been introduced by Schindler et al. in 2005. This model reduces the black-box property of DL and eases the architecture design for every real-world crypto-system as we define theoretical complexity bounds which only depend on the dimension of the (reduced) trace and the targeting variable over F2n . We validate our theoretical proposition through simulations and public datasets on a wide range of use cases, including multi-task learning, curse of dimensionality and masking scheme.
Speeding Up Multi-Scalar Multiplication over Fixed Points Towards Efficient zkSNARKs
Authors: Luo Guiwen , Fu Shihui , Gong Guang
Published: March 2023

The arithmetic of computing multiple scalar multiplications in an elliptic curve group then adding them together is called multi-scalar multiplication (MSM). MSM over fixed points dominates the time consumption in the pairing-based trusted setup zero-knowledge succinct non-interactive argument of knowledge (zkSNARK), thus for practical applications we would appreciate fast algorithms to compute it. This paper proposes a bucket set construction that can be utilized in the context of Pippenger’s bucket method to speed up MSM over fixed points with the help of precomputation. If instantiating the proposed construction over BLS12-381 curve, when computing n-scalar multiplications for n = 2e (10 ≤ e ≤ 21), theoretical analysis ndicates that the proposed construction saves more than 21% computational cost compared to Pippenger’s bucket method, and that it saves 2.6% to 9.6% computational cost compared to the most popular variant of Pippenger’s bucket method. Finally, our experimental result demonstrates the feasibility of accelerating the computation of MSM over fixed points using large precomputation tables as well as the effectiveness of our new construction.
EVALUATION OF MOBILE APPLICATIONS IN THE TEACHING OF GEOMETRY
Authors: Milinković Marija V.
Published: March 2023

Today’s world implies more and more frequent use of smartphones and their applications in every place and at every moment. In this paper, we will first talk about mobile educational applications in general, and then we will present various research related to the evaluation of mobile educational applications in the teaching of geometry (Bos, Dick, Larkin). Analyzing the relevant literature, the conclusion is drawn that the evaluation of mobile educa- tional applications is important for learning if geometrical content can be successfully carried out according to three aspects: pedagogical, mathematical and cognitive. The pedagogical as- pect implies the effectiveness of the application to assist in learning; the mathematical aspect of mobile educational applications is very often not fully satisfied because the incorrect use of mathematical language is noticeable, as well as the incorrect classification of shapes and objects; the cognitive aspect determines to what extent the application affects the development of students’ thought processes. According to previous research, mobile educational applications such as Co-ordinate Geometry, Transformations and Attribute Blocks were rated highly in all mentioned aspects of the evaluation.
Jismoniy tarbiya fani o‘qituvchisining pedagogik kompetentligi
Authors: Matnazarov Asadbek , Koʻpalov Sanjarbek
Published: March 2023

Maqolada jismoniy madaniyat sohasidagi mutaxassisga qo‘yiladigan pedagogik talablar va sportchilarni tayyorlash jarayonida muomala madaniyati hamda yuqori malakali sportchilarni tayyorlay olish masalalari yoritilgan.
To Study The Antifungal Susceptibility Pattern, Molecular Profiling And Its Sequencing Analysis Of Trichophyton Rubrum Isolated From Human Sample: A Cross Sectional Case Study From Uttar Pradesh, India
Authors: Manoj Kumar Maurya
Published: March 2023

Introduction: There has been a sudden, unexplained surge in dermatophytoses in India since past 5 years. T. rubrum being the most common etiological agent isolated from clinically diagnosed lesions of cutaneus dermatophytosis. It has a significantly higher capacity of transmission than other anthropophilic dermatophytes.
Aim and Objective: To study the Antifungal Susceptibility Pattern , Molecular Profiling and its Sequencing Analysis of  Trichophyton rubrum isolated from human Sample.
Material and Methods: This was a a prospective study carried out in the Department of Microbiology at Rama Medical College Hospital and Research Centre Mandhana, Kanpur for a period of 1 year i.e, March 2017 to March 2018.  A total of 375 clinically suspected cases of superficial fungal infection were collected with proper informed consent. Dermatophytosis was confirmed in cases by direct microscopy and culture methods. Antifungal drug susceptibility profiles,  MIC of isolates were 50 90 determined using the broth microdilution method according to the CLSI guidelines. The DNA isolation was done using the Qiagen DNA extraction kit followed by the PCR. The sequencing methods were used for the genetic analysis of virulence gene for the confirmation.
Results: Out of the total of 375 clinically suspected cases of superficial fungal infection 31 isolates of Trichophyton rubrum were studied.  The ratio of Male were more 27 (87%) as compared to the Female  4 (12.9% ). The maximum number of isolates was found in the Skin 28 (90.3%) followed by the Nail 3 (9.6%). The ITZ was most sensitive toward T. rubrum than KTZ, TBF, and FCZ. The molecular characterization for the detection of  18s gene was performed  which was confirmed by the Sequencing Analysis.
Conclusion: Antifungal resistance against T. rubrum is increasing over the last few decades due to genetic diversity in the fungal genome. The molecular identification is a gold standard technique for the identification of T. rubrum allowing important factor in providing fungal infection prevention and treatment approaches.
A Brief Overview Of Hantavirus Infections
Authors: Shyama sundar Sahu
Published: March 2023

Hantaviruses belong to the Bunyaviridae family as a separate genus. It is currently known that there are over 20 serogenotypes/ seroserotypes and that a number of new types are under investigation. The types of Hantaviruses which infect rodents tend to be specific to specific hosts and are primarily found in specific rodent species. As a result of the various types of Hantaviruses and their target organs, Hantaviruses can cause a variety of diseases. There are two major diseases in the world: hemorrhagic fever with renal syndrome (HFRS) and hemorrhagic fever with the syndrome (HPS). A new strain of Hantavirus has been observed in progressively increasing numbers within the world as a result of an accelerating increase in Hantavirus cases throughout the world, which represents an issue of public health of great concern across the globe. Hantavirus disease is a relatively new disease, however, its spectrum continues to expand as the number of recognized virus types continues to rise. It has been reported that Hantavirus causes human disease in the British Isles, but at this point, the disease is largely unknown. Hanta viral infection may be underestimated, especially in developing countries, due to its mild asymptomatic nature and lack of standardized laboratory diagnosis in hospitals. There are no simple standardized laboratory diagnoses in hospitals due to its asymptomatic and non-specific nature. Presented is an overview of what is currently known about hantaviruses and hantavirus infections, including their properties, classification, laboratory diagnostics, treatment, and prevention.
A STUDY ON THE FORMULATION AND EVALUATION OF HERBAL HAIR OILS
Authors: K Shyam Sundar Rao
Published: March 2023

The traditional medicine of India, Ayurveda, discusses the use of herbals for beauty, which is based on conventional wisdom. An effective and powerful technology in the cosmetics field is herbal cosmetics. There is nothing more ancient than humanity and civilization than the concept of beauty and cosmetics. Therefore, many of them use beauty products which contain herb that order to keep their beauty and youth. Nowadays, organic cosmetics are becoming more accessible to the common people since they are expected to have fewer side effects, as well as an increased level of safety and security. We aim in this study to develop a general-use herbal oil in which a variety of herbs that are readily available to us are utilized and evaluation of the herbal oil formulation was conducted by determining various parameters, such as viscosity, saponification value, pH, etc.
Paediatrics in the Reichsuniversität Straßburg
Authors: Shalvey Aisling
Published: March 2023

This sensitive yet incisive book addresses the medical treatment of children in the occupied city of Strasbourg during Nazi occupation. Exploring more than 1,000 previously undocumented patient files, it illuminates starkly the workings of paediatric care at a pivotal moment in history. Issues of nationality, social class, and diagnosis all contributed to the experience of each child, and here extensive data analysis is deployed to back up poignant individual stories. This is the first ever demographic overview of a vulnerable group who were treated in the hospital of the Reichsuniversität Straßburg. Veering away from the well-established, top-down approach of examining the doctors, instead it makes the patient central to the analysis. A vivid picture emerges of the practical impact that war and occupation had on children who were suffering from illness, revealing how they were affected by Nazi ideology. Establishing a chronology of this important paediatric clinic, the author situates the core historical developments which brought it from establishment with optimistic and idealistic goals, to downfall just three years later when the Allies liberated the city. Based on previously under-utilized primary sources, this volume employs a novel and distinctive analytical framework, using Alltagsgeschichte (the history of everyday life) and patient experience theory to frame medical records and accounts. The book will be relevant to those interested in the history of childhood, politics, occupation and border disputes, psychiatry, medicine, denazification and the postwar era, the history of National Socialism, patient history and the Second World War.
EXCISÃO DE MUCOCELE COM TESOURA DE TECIDOS GOLDMAN-FOX
Authors: De Souza Diego Leonardo , Leite Brandão dos Santos Edcléia , Souza Alves Gustavo , Rizzotti Galvão Vitor , Rodrigues Cleomar Donizeth , Milis Wandelli Victor , Pimentel Galvão Virgílio
Published: March 2023

Este relato tem como objetivo descrever uma técnica para remoção cirúrgica de mucocele labial com pinça de Goldman-Fox para tecidos moles e analisar os aspectos clínicos. Materiais e Métodos: A mucocele do lábio inferior foi totalmente removida com pinça de tecido mole Goldman-Fox. A lesão foi encaminhada para análise histopatológica, que confirmou o diagnóstico clínico de mucocele. Resultados: Após a excisão, houve sangramento mínimo e margens regulares foram obtidas, o que contribuiu para sutura e reparação suave. A lesão foi totalmente removida sem extravasamento de mucosa. Não houve recidiva da lesão após 2 anos de proservação. Conclusões: A excisão com pinça de Goldman-Fox para tratar a mucocele do lábio inferior foi eficaz e sem complicações, com menor tempo operatório, o que é especialmente bom para crianças e para pacientes menos cooperativos. Além disso, esta técnica permitiu a análise histopatológica para confirmar o diagnóstico.
Sustainable Rural Tourism Management: Upgrading eco-friendly and self-sustainable hotels in Costa Rica
Authors: Okot Tom , Sanchez Quiros Jorge , Castro Mejía Carlos
Published: March 2023

Rural tourism represents a social innovative approach with a goal to conserve natural biodiversity where local communities showcase their cultural heritage and biodiversity. Though, it entails more than just visiting an all-inclusive hotel, it requires a holistic business approach that is conscious of the current tourist market demands. These approaches must make the best use of internet-connected gadgets to transmit data, which is translated into transformative actions, with the objective of improving systems adaptability. However, in Costa Rica, tourism accounts for over a quarter of its total export revenue, especially ecotourism as the most significant form of economic tourism activity. This research analyzes the administrative model of eco-friendly-self-sustainable hotels in rural areas of Costa Rica. Additionally, rural tourism also helps to protect the environment and improve livelihoods of communities. Costa Rica has enormous and innumerable opportunities to develop eco-friendly tourism. There are many reasons why we can think of developing this kind of business within the country’s strategic development plans, such as geographical location, natural resources, social and political factors.
Implications of the COVID-19 Pandemic in Retail SMEs Business Management
Authors: Lorente-Martínez Javier
Published: March 2023

Retail SMEs, mainly local and physical, have been one of the most affected businesses during the COVID-19 crisis and yet considered the lifeblood of the European economy. In this paper, we undertake an introductory analysis of the situations that SME retailers have endured. After the analysis of the characteristics of the crisis for retail SMEs, we conclude with three characteristics that companies must foster in such extreme conditions: Resilience, digitalization, and empathy. We propose a framework that gathers, from a point of view of management and organization, some guidelines that can help retail SMEs to assess and improve their responsiveness to the crisis and build new strengths to face the post COVID-19 transformation and subsequent crisis. Together with these reflections, we finally propose some management suggestions and further lines of research.
An Overview of Being Me
Authors: SAĞLAM DEMİRKAN Fatma
Published: March 2023

Existentialism, which is a 20th century movement, does not consider the individual as a mere thinking entity; defines it as an entity who acts, feels, and can show the responsibility of taking his own choices with his free will. The individual who has the courage to make a choice with her free will and realizes herself in line with her actions has become the subject of research by existential thinkers. Although existentialism, researching of the individual the first emerged as a philosophical movement, it later showed its effect in the fields of social sciences such as psychology. Existential understanding, which has been influential in many research areas, has tried to understand and make sense of the individual in the process of "being me".

In this article, the person who can take the responsibility of gaining self is discussed. The study is limited within the framework of the common concepts and phenomena of the philosophical and psychology existential movement. The concepts and facts of the research were examined with the phenomenological approach method. In the study, the elements of the process of being me are which the individual's freedom, anxiety to be self, being hopeful in the face of the uncertainty of the future, being aware of having a limited life, and being involved in the process of being me by making choices. Within the scope of this study, the elements of the process of being me are evaluated by associating them with religion. The following conclusions were reached in the research: Not every individual is active in the process of being a self; some individuals involve the process of being me by making choices despite their experiences of anxiety, despair, and death; while some others do not have the courage to be me in the face of anxiety, hopelessness and death.
The Croatian scholar in his Siberian exile in the second half of the XVIIth century. On Juraj Križanjić’s book collection in Tobolsk
Authors: Shestopalov Igor I.
Published: March 2023

Juraj Križanjić (16181683), one of the seventeenth-century encyclopaedists, who came to Russia from Croatia, was exiled to Tobolsk in 1661, where he spent fifteen years and wrote his best works, including the famous Politika. An attempt is made to identify the range of books and manuscripts possessed by the talented scholar in exile. The author of the article emphasizes that Križanjićs personal collection of books in Tobolsk, despite its relative scarcity, was thoroughly selected and corresponded to the scholars research interests.
Estratégias pedagógicas ativas e contribuições para o ensino de promoção da saúde nas universidades
Authors: Bispo Letícia de Sousa , Carvalho Renan Fernandes , Faria Magda Guimarães de Araujo , Oliveira Marcia Taborda Correa , Melgoza Fernando
Published: March 2023

Objetivo: Identificar as contribuições de estratégias pedagógicas ativas para o ensino-aprendizagem da promoção à saúde no cenário universitário. Métodos: Trata-se de uma revisão integrativa de literatura realizada em junho de 2021 e complementadas em outubro de 2022 com a utilização combinada nos descritores “universidades” AND “promoção da saúde” AND “ensino”, noqual, paralelamente, realizou-se também a busca com os respectivos sinônimos em inglês dispostos no Medical Subject Headings (MeSH). Realizou-se o levantamento nas bases de dados Scientific Eletronic Library Online (Scielo), Literatura Latino-Americana e do Caribe em Ciência da Saúde (Lilacs), Current Nursing and Allied Health Literature (Cinahl), Web of Science e Scopus por intermédio do Portal de Periódicos da Capes. Resultado: Obtiveram-se 4.414 documentos cuja aplicação de filtros e leitura de texto completo culminou em um corpus de análise de 7 artigos distribuídos entre Espanha (n=1), Estados Unidos (n=1), Taiwan (n=1) e Brasil (n=4). As estratégias pedagógicas ativas mais utilizadas desenvolveram-se a partir de recursos das redes sociais como Facebook, o Arco de Maguerez e rodas de conversa, ferramentas sociais como o WhatsApp, oficinas pedagógicas baseadas naproblematização, gamificação, aprendizagem baseada em casos e construções compartilhadas de mídias sociais. Conclusão: A opção pelo uso de estratégias pedagógicas ativas se mostrou coerente com o perfil traçado para o contexto universitário.
RISK FACTORS OF STROKE AND THE HUMANIZATION OF NURSING CARE
Authors: Da Silva Fonseca Lima Gabriely , Aparecida Borges Mariana , Helena Brizido Marinho Barreto Maria
Published: March 2023

Objective: To analyze through a literature review, CVA’S risk factors, nurse’s role in the preparation of the patient’s therapeutic plan after a CVA, the importance of Family support in client’s recovery, as well as the feelings experienced by informal carers. Method: This literature review is the search strategy for selecting articles from the Virtual Health Library databases. Results: Twelve studies were found, the final sample being 8 selected articles, with the criterion of nursing care with the patient after CVA, family support in recovery and risk factors for the pathology. Conclusion: The CVA victim transitions from an autonomous life to dependence on activities of daily living, and is inserted into a new routine of adaptations, generating worries and stress. In this way, the family is fundamental in the patient’s recovery, as it provides emotional support and hope for the client.
POST -PANDEMIC SCENARIO FOR MEDICINE AND PEOPLE
Authors: Carlos L Pinheiro Muniz Janailton
Published: March 2023

The novel coronavirus disease (COVID-19), first reported in China, quickly reached global proportions, which triggered a wave of compulsory confinements imposed by governments in order to ease the pandemic. In this scenario, patients, health workers and the general population are under insurmountable psychological pressure, which can lead to mental health problems, such as depression, anxiety, insomnia. In Brazil, the largest number of cases of the disease were notified in the city of São Paulo. With this in mind, an observational study of individuals participating in the Longitudinal Study of Adult Health (ELSA-Brasil) was proposed, which seeks to analyze and monitor the mental health of 4150 patients during the period of social isolation and restricted commuting, as well as registering their evolution when submitted to psychoeducation and psychotherapy, looking for prevalences of associated psychiatric symptoms. In this study, individuals who sought psychological assistance, who scored with higher levels of severity and had significant worsening in the depression scale will be submitted to online psychotherapeutic sessions, guided by professionals in the fields of Psychiatry and Psychology. Based on this proposal, the possibility of using Telemedicine follows, more specifically, Telepsychiatry and Telepsychology, whose use underwent new revisions in March and April by CFM and CFP, respectively, which involved their exceptional release during the COVID-19 pandemic. With this, the broader use of these means for the follow-up of ELSA patients is sought, through the exploration of new platforms and their application to the exposed context.
MEDICINAL BIOMAGNETISMO IN THE TREATMENT OF PROSTATE CANCER
Authors: Mara Rambo Martini Angela , Neris Cazella Luciane , Martini Yuri , Viapiana Bossa Adriane , Souza Santos Jefferson
Published: March 2023

Prostate cancer (PC) is reported as an important neoplasm worldwide, caused by the uncontrolled multiplication of cells in the prostate. The main risk factors are age over 50 years, family history, genetic susceptibility, hormonal disorders, obesity and environmental factors. Active surveillance of low-risk PC defers aggressive treatment until disease progression and is an increasingly recommended treatment strategy. This strategy aims to reduce costs and decrease treatment-related morbidity without affecting survival. Medicinal Biomagnetism (BM) is based on the distortion of the limit of homeostasis towards hyperacidity and hyperalkalinity of two specific points for each pathogenic microorganism or glandular dysfunction. The induction of loads that are in a vibrational and energetic relationship, by means of medium intensity magnets, greater than 1000 Gauss, corrects or prevents the distortion of the pH of the organs or tissues of the human body. In this way, the neutralization of pathogenic bioenergetic distortions promotes health. The aim of this study was to evaluate the effect of BM in the treatment of prostatic adenocarcinoma, prognostic group 1. After three sessions of BM, the levels of prostate-specific antigen (PSA) decreased and the prostate adenocarcinoma regressed to discrete chronic inflammation. This study represents the first in the evaluation of BM for the treatment of CP and may stimulate further studies in this field that are likely to yield important discoveries.