bluuebunny/crossref_metadata_2025 huggingface dataset:
Big Data Analysis Report on Trial of Obstetrics and Gynecology Medical Damage Liability Dispute Cases in China from 2017 to 2021
Authors: Wu Yushu , Li Jing , Zhang Yong , He Songyue , Wang Zhiyong , Cui Changqing
Published: January 2023

Objective: To analyze the data of the trial cases of medical damage liability disputes in obstetrics and gynecology from 2017 to 2021, with a clear understanding of Chinese medical damage liability disputes. Methods: The data of medical damage liability dispute cases in obstetrics and gynecology during 2017-2021 were collected and analyzed. The analysis directions included (1) The trial types of civil litigation cases in each year; (2) Annual distribution of civil litigation cases in obstetrics and gynecology in an annual year basis; (3) Distribution of the amount of the subject matter and the amount of civil compensation; (4) The geographical distribution of litigation cases; (5) Characteristics of the medical institution as defendant; (6) Distribution of litigation departments in medical institutions; (7) Common causes of action in obstetrics and gynecology cases; (8) Results of common injuries in obstetrics and gynecology cases; (9) Court confirmation of disputes over medical records. Results: According to the data analysis results, the distribution of litigation trial types, annual distribution, compensation amount distribution, regional distribution and other basic data were obtained, and based on the analysis of the characteristics of medical institutions, department distribution, causes of litigation, damage structure and court recognition results were systematically discussed. Conclusion: Although the liability disputes for medical damage in obstetrics and gynecology have been declining in recent years, the problems in medical treatment and management can not be ignored. Attention should be paid to them and medical problems should be avoided.
Effect of Huangqi Fuzheng Decoction on Immune Function in Patients with Breast Cancer Undergoing Postoperative Chemotherapy
Authors: Baokan Jia Na Er
Published: January 2023

Objective: To analyze the application effect of Huangqi Fuzheng decoction in postoperative chemotherapy of breast cancer and its influence on immune function of patients. Methods: Eighty breast cancer patients who underwent surgical treatment from January 2021 to August 2022 were selected and randomly divided into two groups. The control group only received conventional chemotherapy regimen.The observation group was added Huangqi Fuzheng decoction on the basis of the control group. The incidence of adverse reactions of chemotherapy was compared between the two groups,the changes of immune indexes, quality of life score and sleep quality score before and after treatment were compared between the two groups. Results: ① The incidence of adverse reactions in the observation group was lower than that in the control group (P < 0.05). ② The changes of CD4+, CD8+, CD4+/CD8+ in the observation group before and after treatment were higher than those in the control group (P < 0.05). ③ The changes of quality of life score and sleep quality score before and after treatment in the observation group were higher than those in the control group (P < 0.05). Conclusion: The application of Huangqi Fuzheng decoction is helpful to reduce the incidence of adverse reactions of chemotherapy and improve the immune function of patients, so as to improve the quality of life and sleep quality of patients.So it can be widely used.
The Realistic Dilemma and Optimal Path of China's Postgraduate Legal Education System
Authors: Liu Xiang
Published: January 2023

The plight of law graduate education in China is directly related to its educational goals and educational methods. Based on the teaching methods of civil law system and common law system, this paper finds a feasible and optimized way to train qualified legal talents for the construction of the country under the rule of law.
ОЦІНКА АДАПТИВНОГО ПОТЕНЦІАЛУ КОЛЕКЦІЙНОГО МАТЕРІАЛУ МОРКВИ (DAUCUS CAROTA L.) ЗА ПРОЯВОМ ОЗНАК "ЗАГАЛЬНА УРОЖАЙНІСТЬ КОРЕНЕПЛОДІВ" ТА "ВМІСТ β-КАРОТИНУ"
Authors: Pidlubenko І. М. , Ovchinnikova O. P. , Bilenka O. M. , Shtepa L. Yu. , Novichenko V. A.
Published: January 2023

Мета дослідження. Виявити потенційні адаптивні особливості селекційного матеріалу моркви (Daucus carota L.) за показниками «загальна урожайність коренеплодів» та «вміст β-каротину». Методи. Польові, лабораторні, розрахунково-статистичні. Результати. За результатами досліджень у 2018–2020 рр. для агрокліматичної зони Лівобережного Лісостепу України проведено комплексне дослідження параметрів адаптивної здатності зразків моркви Daucus carota L. та визначено перспективні сорти: цінні генетичні джерела для адаптивного відбору. Серед проаналізованих зразків вирізнявся сорт Яскрава, який мав найкращий показник загальної врожайності коренеплодів та адаптивної здатності за цим же показником (X мед=24,33 т/га, СЦГі =15,10). За вмістом β-каротину в коренеплодах для подальших досліджень виділявся зразок Marchew Jadalna, який за роки досліджень показав стабільно високий вміст цієї цінної біохімічної речовини, що знайшло відображення у високій селекційній цінності генотипу СЦГі = 6,47). Ідентифіковано два зразки Kuroda SX і Shantane Red Cord, які показали низьку залежність від умов середовища (bi <1) і є цінними генетичними джерелами для адаптивного відбору. За показником «вміст β-каротину» в коренеплодах моркви за роки досліджень виділено 4 зразки, які мали стабільно високий рівень прояву цієї ознаки: сорт-стандарт Шантане Сквирське (Хмед=8,54/100 г), Marchew Jadalna. (Xmed = 8,49 мг / 100 г), Kuroda SX (Xmed = 7,40 мг / 100 г), Kuroda (Xmed = 7,05 мг / 100 г). Стабільним джерелом прояву ознаки «вміст β-каротину» в коренеплодах став зразок Катрін з bi = 0,64 (bi <1). Висновки. Проведені дослідження дали змогу проаналізувати адаптивний потенціал вихідного селекційного матеріалу моркви (Daucus carota L.) за показниками «врожайність коренеплодів» та «вміст β-каротину». Проведений дисперсійний аналіз польових даних дав змогу виявити екологічно стійкі джерела з високою загальною та питомою адаптивною здатністю за обома досліджуваними показниками.
АДАПТИВНА ЗДАТНІСТЬ ТА СЕЛЕКЦІЙНА ЦІННІСТЬ КОЛЕКЦІЙНИХ ЗРАЗКІВ СОЇ ОВОЧЕВОЇ
Authors: Yatsenko V. V.
Published: January 2023

Анотація. Вирощування адаптивних сортів овочевих культур є основним принципом екологічно чистого землеробства, що дозволяє знизити вплив негативних антропічних факторів на навколишнє середовище і забезпечити населення екологічно безпечною продукцією. Метою досліджень передбачалося виявити ступінь мінливості параметрів індивідуальної продуктивності та адаптивний потенціал рослин сої овочевої. Методи. Дослідження проводили в умовах навчальновиробничого відділу Уманського національного університету садівництва впродовж 2020–2022 рр., використовували колекційні сорти різного еколого-географічного походження. У дослідженні використано польовий та генетико-статистичний методи. Результати. За кількістю пагонів рослини значно варіювали (CV= 6–53 %). За показником кількості бобів на рослині істотно переважали сорт Романтика, сорти Fiskeby V–E5 і Астра – 53,00 і 44,33 шт./росл, що більше на 70,1 і 42,2 %. Варіювання даної ознаки було сильним – CV = 31 %. Кількість насінин стручку була середньоваріабельною – 13 %, а зразки розділилися на дві групи: з двонасінними стручками (Романтика st, Karikachi, ‘Fiskeby V–Е5’, Л 380–2–13) та тринасінними бобами (Fiskeby V, Веста, СибНИИСОХ 6, Sac). Оцінка за масою зелених бобів з однієї рослини виявила низьку спадковість даної ознаки h2 = 0,07), а високою масою бобів характеризувалися зразки Sac, Веста, Fiskeby V, Fiskeby V–E5. За врожайністю бобів едамаме та адаптивністю виділилися зразки Л 380–2–13, Веста, Sac, Fiskeby V, Fiskeby V–E5. Виявлено стресостійкі зразки Sac та Karikachi. Високу врожайність насіння, вищу від стандарту, отримано у зразків Л 380–2–13 (1,75 т/га), Sac (1,95 т/га), Веста (1,79 т/га), Fiskeby V (2,22 т/га), Fiskeby V–E5 (2,46 т/га), які переважали стандарт на 8,0–64,8%. Висновки. Оцінювання колекційних сортів сої овочевого напряму використання за варіабельністю морфологічних ознак та продуктивністю дозволило виділити серед інтродукованих колекційних сортів за комплексом цінних ознак для використання у селекційному процесі сорт Sac для створення нових сортів сої овочевого напряму.
УРОЖАЙНІСТЬ ТА ЯКІСТЬ КАПУСТИ БІЛОГОЛОВОЇ ПІЗНЬОСТИГЛОЇ ЗА РІЗНИХ СИСТЕМ ВИРОЩУВАННЯ
Authors: Ivanin D. V. , Chefonova N. V. , Vitanov O. D.
Published: January 2023

Мета. Визначити ефективність систем вирощування (інтенсивна, адаптивна) на сортах капусти білоголової пізньостиглої у сівозмінах різного типу. Методи. Польовий, хімічний, статистичний. Результати. В середньому за 2014–2016 рр. за результатами біометричних вимірів встановлено, що рослини капусти сортозразка Сelsa Х Молдаванка краще розвивалися, а саме за висотою рослини (39,5 см), кількістю листків (13 шт) та масою головки (1,22 кг) за адаптивної системи. Найбільш оптимальним сортом для вирощування за адаптивної системи є сортозразок Сelsa Х Молдаванка (38,1 т/га ) з товарністю 86 %, а сортозразок Столична Х Ladena (Слобожаночка) та сорт Харківська супер (36,0–36,4 т/га) краще вирощувати за інтенсивної системи. В середньому за роки досліджень якість продукції капусти сорту Харківська супер та сортозразків Сelsa Х Молдаванка, Столична Х Ladena (Слобожаночка) краща за адаптивної системи вирощування. Висновки. За показниками росту та розвитку рослини капусти білоголової пізньостиглої, вирощені за адаптивної системи, не поступаються рослинам, вирощеним за інтенсивної системи. Доведено, що за адаптивної системи найкраще вирощувати сортозразок Сelsa Х Молдаванка, який забезпечує рівень урожайності головок капусти 38,1 т/га. Капуста білоголова пізньостигла сортозразків вітчизняної селекції при вирощуванні за адаптивної системи має конкурентоспроможність на рівні продукції з інтенсивної.
UNCONVENTIONAL METHODS OF MANUFACTURING THIN WIRES FOR APPLICATION AS INPUT MATERIAL IN ADDITIVE MANUFACTURING. PART 2: DRAWING OF Fe-BASED ALLOY WIRES
Authors: BURDEK Marek , ADAMCZYK Mariusz , MARSZOWSKI Krzysztof
Published: January 2023

The article presents the technology of drawing thin wires made from selected iron-based alloys for use in additive manufacturing using WAAM method. The final technology of wire production was developed with the use of a drawing bench, depending on the deformed material. Steel wires with a diameter of 1 mm and mechanical properties adapted to the 3D printer were produced.
Acidente de trajeto e sua caracterização após a revogação do direito às horas In Itinere
Authors: Deluca Ana Paula
Published: January 2023

As constantes mudanças na legislação brasileira são fenômenos corriqueiros e sempre presentes para o cidadão trabalhador. Nesse contexto, este trabalho tem como objetivo demonstrar a dimensão que a Lei n.º 13.467/2017 da Reforma Trabalhista que trouxe, em especial, sobre a posição das horas itinerárias, bem como a comparação com a redação da legislação anterior e após a reforma e a situação dos empregados e seus contratos de trabalho. Para isso, realizou-se uma revisão bibliográfica, fundamentada na literatura, bem como em legislações e jurisprudências. Como resultados, nota-se que em efeito a essas mudanças, surgiu a repercussão da caracterização do acidente de trajeto como acidente de trabalho, pois o mesmo gerava direitos atinentes em virtude de sua aplicação antes da reforma, demonstrando, assim, os dispêndios constantes dos empregados no percurso casa-trabalho e trabalho-casa após a revogação das horas in itinere e o efeito deste resultado sobre o acidente de trajeto. E, em consequência dessas alterações, a conclusão do presente estudo denotou um determinado conflito, tanto jurisprudencial como doutrinário, visto as constantes mudanças corriqueiras na legislação trabalhista, as quais não geram preservação e solidez ao trabalhador, ficando à mercê das supressões legislativas.
Evaluation of the efficiency in the use of anionic polyacrylamide, organosilane and sulfonate for the stabilization of roads with traffic low volume in the Peruvian highlands above 2000 m.s.n.m [Evaluación de la eficiencia en la utilización de poliacrilamida aniónica, organosilano y un sulfonatado para la estabilización de carreteras de bajo volumen de tránsito en la sierra peruana sobre los 2000 m.s.n.m]
Authors: Villanueva Flores Silvia Monica
Published: January 2023

The objective of the research was to evaluate the efficiency in the use of anionic polyacrylamide, organosilane and a sulfonate for the certainty of low volume traffic roads in the Peruvian highlands above 2000 m.s.n.m. Tests were carried out with the selected materials; Subgrade, Quarry 1 and Quarry 2, with the stabilizers, which obtained CBR values ​​above 40% minimum for paved roads. The best expression option in terms of its mechanical physical behavior was used using an anionic polyacrylamide dosage of 1kg/m3.
The Future Cities that Were Shaped by Visual Culture of 1980’s SCI-FI Movies
Authors: Işıkören Serkad Hasan , Işıkören Derin
Published: January 2023

At the turn of the 20th century modernism was it’s own way. Futurism has its manifesto by expressing of the celebration of the new era. It was underlining the fact that new era should destroy all previous ties of traditionalism and one should turn its head to the developments of industrial revolution. Architecture created its own dynamics by examining the tradition, later combining it with revolution and at the end creating the vocabulary of its own language. As Pioneer architect Le Corbusier illustrated the appearance of feature cities in his sketches some other new art forms were on its way. Meanwhile; cinema as the new art form, visualised and rather prophecisied future cities as architects of the new world foreseen the facts of the future appearance of the cities. The aim of this paper is to investigate the effects of the cinema industry of 1980’s on future cities and the reflections of three dimensional graphics on architectural facades of the future cities by examining the movie based sci-fi hallucinations that come to be true in today’s cities.
The Impact of Tall Buildings within the Existing and Historical Urban Environment
Authors: Ghazaleheniya Ismaeel , Özsavaş Akçay Ayten
Published: January 2023

The rapid growth of the world increased the demand of the tall buildings as a result of physical, social and economic needs. Tall Buildings with their great size and large impact on the existing urban environment and especially on the historical one became like a double-edged sword. They may be an active city element and become a landmark that has its own value, preserve and respect the built surrounding, or it will be a portion that disfigure the urban skyline of the city and become a visual deformation within its space. The most important point that should be considered while designing a tall building is the harmony between it and its built surrounding. Design considerations regarding physical integration of the tall building with the context around it must be handled with more care than any other conventional building. In order to minimize the damage on the historical urban heritage and the existing built environment maximizing the useful landscape provided by its footprint on the site should be aimed. This paper aims to evaluate the impacts regarding the integration of tall buildings within the existing and historical urban environment. A holistic approach clarifying this integration as a way of designing an efficient urban element also aimed to be discussed in this paper.
Documentation of Old Urban Areas for Regeneration Ideas in the Future, Khanaqa Neighborhood as Case Study
Authors: Ibrahim Shaymaa Jalil , Erçin Çilen , Kharbosh Carol Kamil Toma
Published: January 2023

Globally, as the inhabitants of urban areas continueto grow, considerable pressure is placed on resources, necessitating the immediate need for effectiveimprovements to theinfrastructure in the area, particularly in terms of shelter, clean water, andwaste. The builtenvironment is asignificant component of urban life. Controlling urban zonesis thus one ofthe21st century's importantchallengesin urbandevelopment, Erbil city is not far from this challenge. Erbil is one of the old cities in Iraq that consists of many old urban areas which inyears they will lose the ability to maintain their physical structure. Accordingly documenting old neighborhoods of Erbil city could play a staminal role in helping future regeneration works. The study conducts a documentation process that preparesa set of layered maps of the existing situation of the Khanaqahneighborhood that help in regeneration works within the area in the future. Khanaqa neighborhood is one of the oldest bad-conditioned areas in Erbil city. Thisarea did notreceive any maintenance or renovation works besides its obvious problems such asCrowding problems because it’s inside the central business district, traffic problemsbecause of the development of the city, lack of car parking, there is no consideration for pedestrian, the lake of greenery, and the exhausted situation of the neighborhood are main problems. The aim of the study is to describe all the problems that faced the neighborhood to be a ready document for oncoming renovation works. The research demonstrates a descriptive methodology to explain the weak and strongpoints of the area through observationofthe condition of the buildings, streets,and facilities in the neighborhood and comparingthem with the standards. The research finds that the area needs to have a comprehensive renovation process to retain its cultural and historical valuesfrom deteriorationand on the other hand to enrich the quality of commercial activities and social interactions in the area.
The Correlation between Principals’ Managerial Competence, Academic Supervision Competence, Entrepreneurial Competence, and Teachers’ Motivation for Achievement throughout State Vocational High Schools
Authors: Mas Sitti Roskina , Masaong Abdul Kadim , Djafar Hairanti , Marhawati Besse
Published: January 2023

This present study aimed to identify the correlation between principals’ managerial competences, academic supervision competence, entrepreneurial competencies, and teachers’ motivation for achievement throughout state vocational high schools in the city of Gorontalo. It relied on a quantitative method with a correlational technique and collected the data from a questionnaire using the Likert scale. The results revealed that principals’ managerial competence and teachers’ motivation for achievement had a positive and significant correlation with a correlation coefficient of 0.376 (37.6%); the correlation between principals’ academic supervision competence and teachers’ motivation for achievement was positive and significant with the correlation coefficient of 0.459 (45.9%); the correlation between principals’ entrepreneurial competence and teachers’ motivation for achievement was positive and significant with the correlation coefficient of 0.312 (31.2%); principals’ managerial, academic supervision, and entrepreneurial competencies and teachers’ motivation for achievement reached a positive and significant correlation with the correlation coefficient of 0.546 (54.6%).
Online Friendships and the Bird’s Nest Drawing in the Age of the Internet
Authors:   , Wong Ian
Published: January 2023

This study was a qualitative exploration of friendships facilitated through the internet and online video games. The goal was to investigate how online friendships compare to in-person friendships in terms of quality. Three English-speaking participants who played an online video game and had an online friendship provided unique case studies describing the differences between an online and in-person friendship. The Bird Nest Drawing art assessment by Kaiser (1996; 2016) revealed themes of attachment security which helped explain the variations in the friendships. The findings of this study opened the topic of online friendships for further exploration in the field of art therapy, both in research and in a therapy setting.
Stereoselective Synthesis of Novel (±)-trans-Dihydronarciclasine Analogues: Preparation of a Pivotal Intermediate Containing Two Methoxy Substituents
Authors: Lévai Balázs , Varró Gábor , Simon András , Hegedűs László , Kádas István
Published: January 2023

An efficient stereoselective synthesis of a pivotal intermediate, a cyclic allyl alcohol derivative containing two methoxy groups [(±)-22], using for the preparation of (±)-trans-dihydronarciclasine analogues was elaborated starting from easily available and inexpensive methyl gallate. This new synthetic route consists of 17 reaction steps, and provides an opportunity to obtain the wanted alkaloid derivative containing an additional methoxy group at position 11, in the ring A of the phenanthridone scaffold.
Investigation of Carbon Footprints of Three Desalination Technologies: Reverse Osmosis (RO), Multi-Stage Flash Distillation (MSF) and Multi-Effect Distillation (MED)
Authors: Do Thi Huyen Trang , Tóth András József
Published: January 2023

Nowadays, the drinking water shortage is increasing, mainly due to rapid population growth, climate change, wasteful overuse of water, and pollution. Under the current circumstances, a quarter of the world's population will not have access to good quality drinking water. Thus, another solution must be adopted in areas with insufficient freshwater. One possible line is the desalination of seawater, one of the most practical solutions to solve the problem of drinking water shortage along the oil availability shore and continues to expand globally. Water produced may also be utilized for irrigation, reducing a region's reliance on imports, contributing to the local economy, and improving food supplies. However, this process is not a consequences-free procedure; it may cause several environmental and human health problems.The three most applied desalination technologies are reverse osmosis (RO), multi-stage flash distillation (MSF), and multi-effect distillation (MED). In this study, the emissions of greenhouse gases (GHGs) of drinking water produced from seawater using these three technologies with fossil and renewable energy sources were investigated based on two methods: life cycle assessment (LCA) using SimaPro life cycle analysis software and carbon footprints. As a result, RO technology has significantly lower CO2 emissions than thermal technologies. The RO combined renewable energy is the most environmentally friendly; provides outstanding benefits in terms of human health and ecosystem quality. This technology may still evolve in the future to produce longer-lasting, cheaper membranes, and the energy requirements of this process are lower with applying modern energy recovery systems.
Peculiar Features of Formation of the Phase Composition of Black Clinker Ceramics
Authors: Khomenko Olena , Sribniak Nataliia , Ivchenko Viktoriia , Hretsai Svitlana , Teliushchenko Ivan , Halushka Serhii
Published: January 2023

This paper examines the peculiarities of the phase composition of black clinker bricks based on the ceramic masses of Kerameya enterprise (Sumy, Ukraine). The principles of charge choice are given considering the ratio of coloring oxides Fe2O3, CoO, MnO2, Mn3O4 and CuO. We found that the phase composition of black clinker bricks after firing at 1100 °С is mainly represented by quartz, microcline, mullite, residues of biotite, as well as hematite and hausmannite as the coloring phases, and also small amounts of cuprite. To produce black ceramic bricks on the basis of clay composition, we need to take 13.5 wt% elements with the ratio of Mn: Fe: Ti: Cu equal to 4.2: 7.7: 0.5: 1.1. Such ceramic mass is already used to produce ceramic clinker bricks with water absorption of 5%, mechanical compressive strength of more than 35 MPa and frost resistance of more than 150 freezing and thawing cycles.
PEMETAAN DISTRIBUSI CURAH HUJAN RATA-RATA MENGGUNAKAN METODE ISOHYET DI WILAYAH KABUPATEN TANGERANG
Authors: Nurhijriah Lutfiah , Ruhiyat Yayat , Saefullah Asep , Rostikawati Diana Ayu
Published: January 2023

The purpose of this study was to obtain information related to the distribution mapping of average rainfall in the Tangerang Regency area. Hydrological analysis is needed in determining the average rainfall in an area, one of which is by using the Isohyet method. The isohyet method is a method of making a connecting line that brings together points of the same rain depth. The research was conducted by analyzing rainfall data in the Tangerang Regency area in the last five years, namely the period 2016 to 2020. The research data were obtained from three observation stations, namely: 1. Budiarto Curug Meteorological Station, 2. Pondok Betung Climatology Station, and 3. Ciputat Region II BMKG Station.  This research was conducted in two activities, namely: 1. Rainfall data collection, and 2. Data processing using Minitab and ArcGIS applications. Based on the results of processing rainfall data for the 2016-2020 period at three observation stations, the P-Value was 0.115 and the Kolmogorof Smirnov test value was 0.103 for heading 1, P-Value was 0.115 and the Kolmogorof Smirnov test value was 0.103 for heading 2, and P-Value < 0.010 and the Kolmogorof-Smirnov test value of 0.195 for heading 3. The results of the calculation of rainfall from the three observation posts show that the rainfall in the Tangerang Regency area is normally distributed. The results of the rainfall mapping using the Isohyet method also show that the rainfall in the Tangerang Regency area is evenly distributed.
Analisis Faktor Unsur Cuaca terhadap Perubahan Iklim Di Kabupaten Pasuruan pada Tahun 2021 dengan Metode Principal Component Analysis
Authors: Sunarmi Nani , Kumailia Elok Nurul , Nurfaiza Nanin , Nikmah Afifatul Khoirun , Aisyah Hani Nur , Sriwahyuni Indah , Lailly Shella Nur
Published: January 2023

Cuaca menjadi  indikator perubahan iklim di bumi yang mempengaruhi berbagai aspek  kehidupan.  Peran dan pengaruh cuaca sangat bergatung pada unsur-unsur yang mempengaruhinya. Penelitian ini bertujuan untuk menganalisis faktor unsur cuaca yang berpengaruh terhadap perubahan iklim yang terjadi kabupaten Pasuruan Jawa timur.  Unsur-unsur cuaca  yang dianalisis meliputi  kelembaban,  curah hujan,  suhu, arah angin, kecepatan angin dan radiasi sinar matahari.  Analisis yang diterapkan dalam penelitian ini terdiri dari analisis deksriptif dan analisis faktor menggunakan metode Principal Component Analysis dengan bantuan aplikasi spss. Data yang digunakan merupakan data sekuder atau data yang sudah ada, data sekunder ini diperoleh dari informasi pada laman Badan Meteorologi Klimatologi dan Geofisika Republik Indonesia. Data yang dikumpulkan merupakan data unsur cuaca untuk kabupaten Pasuruan dalam kurun waktu satu tahun yakni periode  Januari – Desember Tahun 2021. Hasilnya, diperoleh bahwa terdapat dua faktor yang berpengaruh terhadap perubahan iklim yang ada di kabupaten Pasuruan tahun 2021. Faktor 1 yaitu  Kelembapan udara, Curah hujan, Lamanya sinar matahari. Faktor 2 yaitu  suhu, arah angin, kecepatan angin. Yang paling dominan berpengaruh pada perubahan iklim ada di faktor 1 variabel paling dominan pengaruhnya yaitu pada variabel  kelembaban dan lamanya sinar matahari  karena memiliki nilai korelasi 0.960  yang paling tinggi.
Simulation Modeling for Earth to Air Heat Exchanger system by Using MATLAB
Authors: H. Ali Mohammed , Kurjak Zoltan , Beke Janos
Published: January 2023

A MATLAB model was built for the preparation of initial designs for the establishment of an EAHE system for the purpose of heating and cooling buildings. The purpose of creating this model is to save time and effort by creating a new model capable of providing us and specialized designers with initial perceptions of the size of the appropriate system for the functional requirements for the purpose of cooling and heating buildings. A parametric analysis was then performed to evaluate and investigate the factors affecting the efficiency of the EAHE system. It was found that the pipe diameter is directly proportional to the pipe length, and inversely to the airflow velocity, pressure losses, and AFP. Airflow velocity reduced from 77.05 m/s to 0.1926 m/s, and AFP decreased from 9223 W to 0.058 W when diameter increased from 0.1 m to 2 m. The inlet air temperature affects the length of the pipe in four phases, it is inversely proportional in the first and third phases and directly in the second and fourth phases. These phases depend on the values of soil, inlet, and outlet temperature. This paper presents new equations to determine these phases to determine excluded range which is recommended should not use an inlet air temperature value through this range. The pipe number is directly proportional to pipe length. Pipe length increased from 57.16 m to 344.9 m when the pipe number increased from 1 to 10 pipes. The number of pipes has no influence on the overall airflow velocity or total heat transfer. The length of the pipe is directly proportional to the soil temperature in the first and third phases and inversely proportional in the second and fourth phases. Designers could get an idea of this range by utilizing the equations presented in this paper. There is no direct effect between the soil temperature and power, but rather it affects it through the length of the pipe, as it is directly proportional to pipe length.
3D ANIMATION DESIGN "SCIENCE, LANTERNS TO HEAVEN" USING THE POSE-TO-POSE METHOD
Authors: Apriliyanti Desy , Fadila Juniardi Nur , Nugroho Fresy
Published: January 2023

In today's era, technology and communication have experienced very rapid development. Islamic values ​​raised through the media are an effort in people's lives today. Including through the media of 3D animated films that rely on entertaining audio-visuals and messages conveyed through animated films can also be easily captured by the audience. In addition, the selection of animated films is based on the number of animated films circulating on social media such as YouTube and other electronic media, and this film can affect the attention of many people. Animated film designed by the author with the theme of the importance of studying can lead to Allah SWT's heaven. Making this animated film will use Blender software version 2.80. The method used is "Pose-to-Pose" by determining each key pose movement to produce a good movement. Using this method makes the work more effective or faster; if there is an error in the pose, it can be easily corrected. The design of the 3D animated film entitled "Science, Lantern Towards Heaven" is expected to be useful for the audience and take the moral message in it, which is to increase enthusiasm for learning or studying
Parasites and their impact on thick-shelled river mussels Unio crassus from two populations in Luxembourg
Authors: Lewisch E , Arnold F , Fuehrer HP , Harl J , Thielen F , El-Matbouli M
Published: January 2023

The thick-shelled river mussel Unio crassus Philipsson, 1788 is a species native to many European habitats, with declining populations. The impact of parasite communities on health status of this species is poorly understood. In this study, parasites of 30 U. crassus specimens from the Our and Sauer Rivers in Luxembourg were identified morphologically and, in some cases, using molecular genetic methods. The findings were correlated to selected parameters (total length, visceral weight, shell lesions, gonadal stage). The 2 populations did not differ in shell length, visceral weight, number of males and females, gonadal scoring, shell lesions, and the occurrence of glochidia. The prevalence and infestation intensities of detected Trichodina sp., Conchophthirus sp., and freshwater mite larvae did not differ between the 2 populations, whereas the prevalence and infestation intensities of mite eggs, nymphs, and adults were significantly higher in the Sauer River. Rhipidocotyle campanula and European bitterling Rhodeus amarus larvae were only present in the Sauer. Histopathology revealed the destruction of the gonads by R. campanula and tissue damage by the mites. The only significant correlation of the selected parameters was a positive correlation between R. amarus occurrence and total length as well as a negative correlation between R. amarus occurrence and gonadal stage. In the Sauer River, 2 mussels were found to be hermaphrodites.
Management of Neuropsychiatric Symptoms for Chronic Traumatic Encephalopathy
Authors:   University of Florida College of Medicine, Gainesville, FL, USA., Fusco Anna , Olowofela Bankole ,   University of Florida College of Medicine, Gainesville, FL, USA., Dagra Abeer ,   University of Florida College of Medicine, Gainesville, FL, USA., Hatem Rami ,   University of Florida College of Medicine, Gainesville, FL, USA., Pierre Kevin ,   University of Florida Department of Radiology, Gainesville, FL, USA., Reza Hosseini Siyanaki Mohammad ,   Department of Neurosurgery, University of Florida, USA., Lucke–Wold Brandon ,   University of Florida Department of Neurosurgery, Gainesville, FL, USA
Published: January 2023

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repeated head injury.
Deviant and Heretical–Carcinoma Cervix
Authors:   Consultant Histopathologist, A.B. Diagnostics, A–1, Ring Road, Rajouri Garden, New Delhi 110027, India., Bajaj Anubha
Published: January 2023

Carcinoma cervix is an invasive epithelial neoplasm comprised of neoplastic cells demonstrating varying degrees of squamous differentiation.
Dimensions of Operational Stress in the Nigerian Navy: Selected Samples of Combatant, Artisan and Retired Naval Personnel in Nigeria
Authors:   Department of Psychology, Baze University of Nigeria, Nigeria, D. Osa-Afiana Damian
Published: January 2023

This study examined dimensions of stress among sample of selected Nigerian Navy personnel in Lagos, Calabar, Jaji, in Kaduna Nigeria.
Religious and cultural influences: An exposition
Authors: Emeng Gideon Imoke , Okafor Justin Oyebuchi
Published: January 2023

Religion and culture seem to be complicated concepts from an international relations viewpoint. Scholars and philosophers have, after all, long discussed the meaning of these words and their influence on our understanding of the social world. The purpose of this paper is to provide a diagram of religion and culture in international politics. The purpose was to highlight the significance of religious and cultural influences in understanding world events. The process consisted of identifying the characteristics of each concept and analyzing their impact on personal, national, and international experiences. This work argues that understanding religious and cultural issues is necessary to engage in some of the most important discussions about current world affairs. This work submits that there is nothing in modern IR that does not include religion, culture, or both. This research is carried out using critical and contextual analysis methods.
Antibacterial intraosseous implant surface coating that responds to changes in the bacterial microenvironment
Authors: Bai Xin , Yu Jiawei , Xiao Jie , Wang Yanping , Li Zhe , Wang Hao
Published: January 2023

Bone implant-associated infection is one of the most challenging problems encountered by orthopedic surgeons. There is considerable interest in the development of drug-loaded antibacterial coatings for the surfaces of metal implants. However, it is difficult to achieve the stable local release of an effective drug dose for many antibacterial coatings. In the present study, analyses of the thickness and water contact angle of multiple layers confirmed the successful assembly of multilamellar membrane structures. Measurement of the zone of bacterial inhibition indicated gradual degradation of the (montmorillonite [MMT]/hyaluronic acid [HA])10 multilamellar film structure with concentration-dependent degradation during incubation with hyaluronidase solution and Staphylococcus aureus. In vivo results resembled the in vitro results. Overall, the findings confirm that the (MMT/HA-rifampicin)10 multilamellar film structure exhibits good antibacterial properties and excellent biocompatibility. Further studies of the clinical potential of the antibacterial coating prepared in this experiment are warranted.
Maintenance of multipotency of bone marrow mesenchymal stem cells on poly(ε-caprolactone) nanoneedle arrays through the enhancement of cell-cell interaction
Authors: Ren Xiaoxue , Gao Xiaoting , Cheng Yicheng , Xie Lingxia , Tong Liping , Li Wei , Chu Paul K. , Wang Huaiyu
Published: January 2023

Mesenchymal stem cells (MSCs), with high self-renewal ability and multipotency, are commonly used as the seed cells for tissue engineering. However, the reduction and loss of multipotential ability after necessary expansion in vitro set up a heavy obstacle to the clinical application of MSCs. Here in this study, we exploit the autologous crystallization ability of biocompatible poly (ε-caprolactone) (PCL) to obtain uniformly distributed nanoneedle arrays. By controlling the molecular weight of PCL, nanoneedle with a width of 2 μm and height of 50 nm, 80 nm, and 100 nm can be successfully fabricated. After surface chemical modification with polydopamine (PDA), the water contact angle of the fabricated PCL nanoneedle arrays are reduced from 84° to almost 60° with no significant change of the nanostructure. All the fabricated substrates are cultured with bone marrow MSCs (BMMSCs), and the adhesion, spreading, proliferation ability and multipotency of cells on different substrates are investigated. Compared with the BMMSCs cultured on pure PCL nanoneedle arrays, the decoration of PDA can improve the adhesion and spreading of cells and further change them from aggregated distribution to laminar distribution. Nevertheless, the laminar distribution of cultured cells leads to a weak cell-cell interaction, and hence the multipotency of BMMSCs cultured on the PCL-PDA substrates is decimated. On the contrary, the pure PCL nanoneedle arrays can be used to maintain the multipotency of BMMSCs via clustered growth, and the PCL1 nanoneedle array with a height of 50 nm is more promising than the other 2 with regard to the highest proliferation rate and best multipotential differentiation ability of cultured cells. Interestingly, there is a positive correlation between the strength of cell-cell interaction and the multipotency of stem cells in vitro. In conclusion, we have successfully maintained the multipotency of BMMSCs by using the PCL nanoneedle arrays, especially the PCL1 nanoneedle array with a height of 50 nm, as the substrates for in vitro extension, and further revealed the importance of cell-cell interaction on the multipotency of MSCs. The study provides a theoretical basis for the behavioral regulation of MSCs, and is instructive to the design of tissue engineering scaffolds.
Mechanism of action and therapeutic effects of oxidative stress and stem cell-based materials in skin aging: Current evidence and future perspectives
Authors: Qian Huan , Shan Yihan , Gong Ruicheng , Lin Danfeng , Zhang Mengwen , Wang Chen , Wang Lu
Published: January 2023

Aging is associated with multiple degenerative diseases, including atherosclerosis, osteoporosis, and Alzheimer’s disease. As the most intuitive manifestation of aging, skin aging has received the most significant attention. Skin aging results from various intrinsic and extrinsic factors. Aged skin is characterized by wrinkles, laxity, elastosis, telangiectasia, and aberrant pigmentation. The underlying mechanism is complex and may involve cellular senescence, DNA damage, oxidative stress (OS), inflammation, and genetic mutations, among other factors. Among them, OS plays an important role in skin aging, and multiple antioxidants (e.g., vitamin C, glutathione, and melatonin) are considered to promote skin rejuvenation. In addition, stem cells that exhibit self-replication, multi-directional differentiation, and a strong paracrine function can exert anti-aging effects by inhibiting OS. With the further development of stem cell technology, treatments related to OS mitigation and involving stem cell use may have a promising future in anti-skin aging therapy.
Case report: Intraosseous hemangioma of the lateral clavicle treated by surgical resection and reconstructed by three-dimensional-printed personalized prosthesis
Authors: Li Zhuangzhuang , Zou Chang , Lu Minxun , Zhang Yuqi , Gong Taojun , Wang Jie , Luo Yi , Zhou Yong , Min Li , Tu Chongqi
Published: January 2023

Background: Intraosseous hemangiomas occurring the clavicle is uncommon. Reconstruction of the clavicle is suggested to maintain the normal shoulder joint function and prevent adverse outcomes. Complex anatomy shape of the clavicle remains a great challenge for prosthetic reconstruction of the clavicle.

Case presentation: A 37-year-old female with no conclusive history of trauma presented with progressive mass at the right lateral clavicle for 5 years. The patient was treated by surgical resection and reconstructed by three-dimensional-printed personalized prosthesis. Postoperatively radiographic examinations revealed a good position of the prosthesis, neither breakage nor loosening was detected. The right shoulder mobility returned to approximate level of preoperative shoulder 2 months after surgical reconstruction, with the range of motion of flexion 80°, extension 40°, abduction 80°, adduction 30°, external rotation 55°, and internal rotation 60°. The patient maintained the normal shoulder function during the 48 months follow-up period. There was no pain during shoulder motion. The Musculoskeletal Tumor Society Score (MSTS) score was 29 and the Functional Evaluation Form recommended by the American Shoulder and Elbow Surgeons (ASES) score was 95.

Conclusion: 3D-printed personalized prosthesis is a good option to reconstruct the lateral clavicle bone defect and restore the shoulder support structure. It maintains the normal shoulder joint function and avoids adverse effects on daily activities after claviculectomy.
Unveiling the secrets of marine—derived fucoidan for bone tissue engineering—A review
Authors: V. K. Anupama Devi , Udduttula Anjaneyulu , Jaiswal Amit Kumar
Published: January 2023

Biomedical uses for natural polysaccharides of marine origin are growing in popularity. The most prevalent polysaccharides, including alginates, agar, agarose and carrageenan, are found in seaweeds. One among these is fucoidan, which is a sulfated polysaccharide derived from brown algae. Compared to many of the biomaterials of marine origin currently in research, it is more broadly accessible and less expensive. This polysaccharide comes from the same family of brown algae from which alginate is extracted, but has garnered less research compared to it. Although it was the subject of research beginning in the 1910’s, not much has been done on it since then. Few researchers have focused on its potential for biomedical applications; nevertheless, a thorough knowledge of the molecular mechanisms behind its diverse features is still lacking. This review provides a quick outline of its history, sources, and organization. The characteristics of this potential biomaterial have also been explored, with a thorough analysis concentrating on its use in bone tissue engineering. With the preclinical research completed up to this point, the fucoidan research status globally has also been examined. Therefore, the study might be utilized as a comprehensive manual to understand in depth the research status of fucoidan, particularly for applications related to bone tissue engineering.
Repurposing existing products to accelerate injury recovery (REPAIR) of military relevant musculoskeletal conditions
Authors: Clark Andrew R. , Mauntel Timothy C , Goldman Stephen M , Dearth Christopher L.
Published: January 2023

Musculoskeletal injuries (MSKIs) are a great hindrance to the readiness of the United States Armed Forces through lost duty time and reduced operational capabilities. While most musculoskeletal injuries result in return-to-duty/activity with no (functional) limitations, the healing process is often long. Long healing times coupled with the high frequency of musculoskeletal injuries make them a primary cause of lost/limited duty days. Thus, there exists an urgent, clinically unmet need for interventions to expedite tissue healing kinetics following musculoskeletal injuries to lessen their impact on military readiness and society as a whole. There exist several treatments with regulatory approval for other indications that have pro-regenerative/healing properties, but few have an approved indication for treating musculoskeletal injuries. With the immediate need for treatment options for musculoskeletal injuries, we propose a paradigm of Repurposing Existing Products to Accelerate Injury Recovery (REPAIR). Developing treatments via repurposing existing therapeutics for other indications has shown monumental advantages in both cost effectiveness and reduced time to bring to market compared to novel candidates. Thus, undertaking the needed research efforts to evaluate the effectiveness of promising REPAIR-themed candidates has the potential to enable near-term solutions for optimizing musculoskeletal injuries recovery, thereby addressing a top priority within the United States. Armed Forces. Herein, the REPAIR paradigm is presented, including example targets of opportunity as well as practical considerations for potential technical solutions for the translation of existing therapeutics into clinical practice for musculoskeletal injuries.
Not a waste: Wastewater surveillance to enhance public health
Authors: Gitter Anna , Oghuan Jeremiah , Godbole Anuja Rajendra , Chavarria Carlos A. , Monserrat Carlos , Hu Tao , Wang Yun , Maresso Anthony W. , Hanson Blake M. , Mena Kristina D. , Wu Fuqing
Published: January 2023

Domestic wastewater, when collected and evaluated appropriately, can provide valuable health-related information for a community. As a relatively unbiased and non-invasive approach, wastewater surveillance may complement current practices towards mitigating risks and protecting population health. Spurred by the COVID-19 pandemic, wastewater programs are now widely implemented to monitor viral infection trends in sewersheds and inform public health decision-making. This review summarizes recent developments in wastewater-based epidemiology for detecting and monitoring communicable infectious diseases, dissemination of antimicrobial resistance, and illicit drug consumption. Wastewater surveillance, a quickly advancing Frontier in environmental science, is becoming a new tool to enhance public health, improve disease prevention, and respond to future epidemics and pandemics.
Application and trend of bioluminescence imaging in metabolic syndrome research
Authors: Li Shirui , Wang Kang , Wang Zeyu , Zhang Wenjie , Liu Zenglin , Cheng Yugang , Zhu Jiankang , Zhong Mingwei , Hu Sanyuan , Zhang Yun
Published: January 2023

Bioluminescence imaging is a non-invasive technology used to visualize physiological processes in animals and is useful for studying the dynamics of metabolic syndrome. Metabolic syndrome is a broad spectrum of diseases which are rapidly increasing in prevalence, and is closely associated with obesity, type 2 diabetes, nonalcoholic fatty liver disease, and circadian rhythm disorder. To better serve metabolic syndrome research, researchers have established a variety of animal models expressing luciferase, while also committing to finding more suitable luciferase promoters and developing more efficient luciferase-luciferin systems. In this review, we systematically summarize the applications of different models for bioluminescence imaging in the study of metabolic syndrome.