bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Energy-Absorbing Device for Motion Suppression in Deep-Sea Floating Platforms
Authors: Zeng Xiaohui , Yu Yang , Zhang Liang , Liu Qingquan , Wu Han
Published: December 2014

Deep-sea floating platforms are one of the most important large structures for ocean energy exploitation. A new energy-absorbing device named S-shaped Tuned Liquid Column Damper (TLCD) has been invented for the suppression of the horizontal motion and vertical in-plane rotation of a deep-sea floating platform. A conventional tuned liquid column damper has a U-shaped water tunnel to absorb the excessive energy of the main structure. The application of U-shaped dampers in deep-sea floating platforms is difficult due to the restriction of a large horizontal length. A novel S-shaped damper is proposed to retain the same amount of liquid using a shorter S-shaped tunnel. Theoretical and experimental works are conducted and prove that an S-shaped damper needs less than half the horizontal length to provide the same suppression as a U-shaped damper. A coupling calculation model is proposed and followed by the sensitivity analysis. The study demonstrates the applicability of the novel S-shaped damper for the motion suppression in deep-sea floating platforms.
The Role of Energy Quality in Shaping Long-Term Energy Intensity in Europe
Authors: Gentvilaite Ruta , Kander Astrid , Warde Paul
Published: December 2014

On the European aggregate level there is an inverted-U curve for long-term energy intensity. In the 19th century aggregate European energy intensity rose, followed by a declining trend during the 20th century. This article discusses the possible explanations for the declining trend during the 20th century and explores the role of energy quality as expressed in energy prices. For the first time a complete set of national energy retail prices covering two centuries has been constructed and used for Britain, while the energy price data previously available for Sweden until 2000 has been updated to 2009. This allows us to explore the role of energy quality in shaping long-term energy intensity. We find no relation between energy quality and energy intensity in the 19th century, while energy quality may have stimulated the declining energy intensity in Europe over the 20th century, but is not the sole or even main reason for the decline. Rather, increased economic efficiency in the use of energy services seems to have been the main driver for the decline after 1970, presumably driven by the information and communication technology.
The 5D Fully-Covariant Theory of Gravitation and Its Astrophysical Applications
Authors: Zhang Tianxi
Published: December 2014

In this paper, we comprehensively review the five-dimensional (5D) fully-covariant theory of gravitation developed by Zhang two decades ago and its recent applications in astrophysics and cosmology. This 5D gravity describes not only the fields, but also the matter and its motion in a 5D spacetime. The greatest advantage of this theory is that there does not exist any unknown parameter, so that we can apply it to explain astrophysical and cosmological issues by quantitatively comparing the results obtained from it with observations and to predict new effects that could not be derived from any other gravitational theories. First, the 5D covariant description of matter and its motion enabled Zhang to analytically derive the fifteenth component of the 5D energy-momentum tensor of matter ( T - 44 ), which significantly distinguishes this 5D gravity from other 5D gravitational theories that usually assumed a T - 44 with an unknown parameter, called the scalar charge s, and, thus, to split the 5D covariant field equation into (4 + 1) splitting form as the gravitational, electromagnetic, and scalar field equations. The gravitational field equation turns into the 4D Einstein’s field equation of general relativity if the scalar field is equal to unity. Then, Zhang solved the field equations and obtained an exact static spherically-symmetric external solution of the gravitational, electromagnetic and scalar fields, in which all integral constants were completely determined with a perfect set of simple numbers and parameters that only depend on the mass and electric charge of the matter, by comparing with the obtained weak internal solution of the fields at a large radial distance. In the Einstein frame, the exact field solution obtained from the 5D fully-covariant theory of gravitation reduces to the Schwarzschild solution when the matter is electrically neutral and the fields are weak in strength. This guarantees that the four fundamental tests (light deflection, gravitational redshift, perihelion advance and radar echo delay) of the 4D Einstein’s general relativity in the case of weak fields are also the tests of the 5D fully-covariant theory of gravitation. In the case of strong fields, especially when the matter is highly charged, however, the results from the 5D fully-covariant theory of gravitation are significantly different from the 4D Einstein’s general relativity. Applying this 5D gravity and its exact field solution, Zhang has recently developed a new redshift mechanism, called electric redshift, a new supernova explosion mechanism with gravitational field shielding, a new gravitationless black hole model, a modified neutron star mass-radius relation, a modified Friedmann equation for the accelerating universe, and so on. This paper provides an overview of this 5D fully-covariant theory of gravitation, including also its solution properties and astrophysical applications.
Health Impact Assessment of Urban Waterway Decisions
Authors: Korfmacher Katrina , Aviles Katia , Cummings B.J. , Daniell William , Erdmann Jared , Garrison Valerie
Published: December 2014

Health impact assessments (HIA) promote the consideration of health in a wide range of public decisions. Although each HIA is different, common pathways, evidence bases, and strategies for community engagement tend to emerge in certain sectors, such as urban redevelopment, natural resource extraction, or transportation planning. To date, a limited number of HIAs have been conducted on decisions affecting water resources and waterfronts. This review presents four recent HIAs of water-related decisions in the United States and Puerto Rico. Although the four cases are topically and geographically diverse, several common themes emerged from the consideration of health in water-related decisions. Water resource decisions are characterized by multiple competing uses, inter-institutional and inter-jurisdictional complexity, scientific uncertainty, long time scales for environmental change, diverse cultural and historical human values, and tradeoffs between private use and public access. These four case studies reveal challenges and opportunities of examining waterfront decisions through a “health lens”. This review analyzes these cases, common themes, and lessons learned for the future practice of HIA in the waterfront zone and beyond.
USP22 Promotes NSCLC Tumorigenesis via MDMX Up-Regulation and Subsequent p53 Inhibition
Authors: Ding Fangbao , Bao Chunrong , Tian Yue , Xiao Haibo , Wang Mingsong , Xie Xiao , Hu Fengqing , Mei Ju
Published: December 2014

Increasing evidence suggests that ubiquitin-specific protease 22 (USP22) has great clinicopathologic significance in oncology. In this study, we investigated the role of USP22 in human NSCLC tumorigenesis along with the underlying mechanisms of action. First, we determined the expression of USP22 in human NSCLC, as well as normal tissues and cell lines. We then studied the effects of USP22 silencing by shRNA on NSCLC cell growth in vitro and tumorigenesis in vivo, along with the effect on the p53 pathway. We found that USP22 is overexpressed in human NSCLC tissues and cell lines. USP22 silencing by shRNA inhibits proliferation, induces apoptosis and arrests cells at the G0/G1 phases in NSCLC cells and curbs human NSCLC tumor growth in a mouse xenograft model. Additionally, USP22 silencing downregulates MDMX protein expression and activates the p53 pathway. Our co-immunoprecipitation analysis shows that USP22 interacts with MDMX in NSCLC cells. Furthermore, MDMX silencing leads to growth arrest and apoptosis in NSCLC cells, and over-expression of MDMX reverses the USP22 silencing-induced effects. Taken together, our results suggest that USP22 promotes NSCLC tumorigenesis in vitro and in vivo through MDMX upregulation and subsequent p53 inhibition. USP22 may represent a novel target for NSCLC treatment.
Oxidative Stress in Obesity: A Critical Component in Human Diseases
Authors: Marseglia Lucia , Manti Sara , D’Angelo Gabriella , Nicotera Antonio , Parisi Eleonora , Di Rosa Gabriella , Gitto Eloisa , Arrigo Teresa
Published: December 2014

Obesity, a social problem worldwide, is characterized by an increase in body weight that results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and leads to several diseases, including metabolic syndrome, diabetes mellitus, cardiovascular, fatty liver diseases, and cancer. Growing evidence allows us to understand the critical role of adipose tissue in controlling the physic-pathological mechanisms of obesity and related comorbidities. Recently, adipose tissue, especially in the visceral compartment, has been considered not only as a simple energy depository tissue, but also as an active endocrine organ releasing a variety of biologically active molecules known as adipocytokines or adipokines. Based on the complex interplay between adipokines, obesity is also characterized by chronic low grade inflammation with permanently increased oxidative stress (OS). Over-expression of oxidative stress damages cellular structures together with under-production of anti-oxidant mechanisms, leading to the development of obesity-related complications. The aim of this review is to summarize what is known in the relationship between OS in obesity and obesity-related diseases.
Lipoprotein-Associated Oxidative Stress: A New Twist to the Postprandial Hypothesis
Authors: Le Ngoc-Anh
Published: December 2014

Oxidative stress is recognized as one of the primary processes underlying the initiation and progression of atherosclerotic vascular disease. Under physiological conditions, the balance between reactive oxygen species (ROS) generation and ROS scavenging is tightly controlled. As part of normal cellular metabolism, regulated oxidative stress is responsible for a variety of cellular responses. Excess generation of ROS that could not be compensated by antioxidant system has been suggested to be responsible for a number of pathological conditions. Due to their short biological half-lives, direct measurement of ROS is not available and surrogate measures are commonly used. Plasma lipoproteins, by virtue of their close interactions with endothelial cells in the vasculature and the susceptibility of their surface lipids to oxidative modification, are perfect biological sensors of oxidative stress in the arterial wall. In particular, with each consumed meal, triglyceride-rich lipoproteins, secreted by the intestine into the circulation, are responsible for the delivery of 20–40 grams of fat to the peripheral tissues. This flux of dietary lipids is accompanied by concomitant increases in glucose, insulin and other meal-associated metabolites. The contribution of postprandial lipemia to the pathogenesis of atherosclerosis has been previously suggested by several lines of investigation. We have extended this hypothesis by demonstrating the acute generation of oxidative epitopes on plasma lipoproteins as well as transient changes in the oxidative susceptibility of plasma lipoproteins.
Effects of Different Sera Conditions on Olfactory Ensheathing Cells in Vitro
Authors: Lu Meng , Dong Jun , Lu Teng , Lv Hongjun , Yang Pinglin , Cheng Zhijian , Li Jin , Liang Baobao , Xu Junkui , Li Haopeng , He Xijing
Published: December 2014

Transplantation of olfactory ensheathing cells (OEC) is a promising therapy in spinal cord injury (SCI) treatment. However, the therapeutic efficacy of this method is unstable due to unknown reasons. Considering the alterations in the culture environment that occur during OEC preparation for transplantation, we hypothesize that these changes may cause variations in the curative effects of this method. In this study, we compared OEC cultured in medium containing different types and concentrations of serum. After purification and passage, the OEC were cultured for 7 days in different media containing 5%, 10%, 15% or 20% fetal bovine serum (FBS) or rat serum (RS), or the cells were cultured in FBS-containing medium first, followed by medium containing RS. In another group, the OEC were first cultured in 10% FBS for 3 days and then cultured with rat spinal cord explants with 10% RS for another 4 days. An MTT assay and P75 neurotrophin receptor immunofluorescence staining were used to examine cell viability and OEC numbers, respectively. The concentration of neurotrophin-3 (NT-3), which is secreted by OEC into the culture supernatant, was detected using the enzyme-linked immunosorbent assay (ELISA). RT-PCR was applied to investigate the NT-3 gene expression in OEC according to different groups. Compared with FBS, RS reduced OEC proliferation in relation to OEC counts (χ2 = 166.279, df = 1, p < 0.01), the optical density (OD) value in the MTT assay (χ2 = 34.730, df = 1, p < 0.01), and NT-3 concentration in the supernatant (χ2 = 242.997, df = 1, p < 0.01). OEC cultured with spinal cord explants secreted less NT-3 than OEC cultured alone (F = 9.611, df = 5.139, p < 0.01). Meanwhile, the order of application of different sera was not influential. There was statistically significant difference in NT-3 gene expression among different groups when the serum concentration was 15% (χ2 = 64.347, df = 1, p < 0.01). In conclusion, different serum conditions may be responsible for the variations in OEC proliferation and function.
Connexin 43 Suppresses Tumor Angiogenesis by Down-Regulation of Vascular Endothelial Growth Factor via Hypoxic-Induced Factor-1α
Authors: Wang Wei-Kuang , Chen Man-Chin , Leong Hon-Fai , Kuo Yu-Liang , Kuo Chun-Yu , Lee Che-Hsin
Published: December 2014

Previous work showed that connexin 43 (Cx43) reduced the expression of hypoxic-induced factor-1α (HIF-1α) in astrocytes. HIF-1α is a master transcription factor for angiogenesis in tumor. Angiogenesis is essential for tumor progression. Here, we investigated the role of Cx43 in vascular endothelial growth factor (VEGF) production and angiogenesis in murine tumor. In the study, mouse B16F10 and 4T1 cells were overexpressed or knockdown with Cx43. The expression profiles as well as activity of the treated cells were examined. Furthermore, reduced Cx43 expression in B16F10 and 4T1 cells causes increased expression of VEGF and enhanced the proliferation of endothelial cells. On the contrary, the expression of VEGF and the proliferation of endothelial were increased in the conditioned medium of Cx43-knockdown tumor cells. We subcutaneously transplanted Cx43-overexpressing B16F10 cells into mice to evaluate the roles of Cx43 in the tumor angiogenesis. Both tumor size and the number of vessels growing in the tumor were markedly decreased compare with control group. Our findings suggest that Cx43 inhibited tumor growth by reducing angiogenesis.
Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration
Authors: Clark Simon , Bishop Paul
Published: December 2014

The recent revolution in age-related macular degeneration (AMD) genetics has demonstrated that genetic alterations affecting the alternative pathway of the complement cascade have a major influence on AMD risk. One of the two most important genetic loci is on chromosome 1 and contains genes encoding complement factor H (FH) and the factor H related proteins (FHR proteins). In macular tissue, especially Bruch’s membrane, relatively high levels of a truncated splice variant of FH called factor H-like protein 1 (FHL-1) are present. Here we discuss how genetic variations may alter the amounts, or by altering their protein sequences, the functions of these proteins. In particular, the common Y402H polymorphism affects the ability of FHL-1 and FH to localize to Bruch’s membrane and the inner choroid because it alters the ability of these complement regulators to bind heparan sulphate (HS) in these structures. In addition, there is an age-related loss of HS from Bruch’s membrane. We hypothesize that a combination of poor binding of the 402H variants of FHL-1 and FH to Bruch’s membrane, combined with a decrease in binding due to age-related HS loss, eventually results in insufficient FHL-1 and FH binding to Bruch’s membrane. This could result in complement activation, inflammation and thereby predispose to AMD.
Hyponatremia and the Thyroid: Causality or Association?
Authors: Pantalone Kevin , Hatipoglu Betul
Published: December 2014

Thyroid disorders, particularly hypothyroidism, have historically been implicated in the development of serum hyponatremia. However, in more recent years, this paradigm has been challenged, and it has been suggested that the link between hypothyroidism and hyponatremia may merely be an association. This review will focus on the thyroid and its link with serum hyponatremia, and review the available literature on the topic.
Linking Coral Reef Remote Sensing and Field Ecology: It’s a Matter of Scale
Authors: Lucas Matthew , Goodman James
Published: December 2014

Remote sensing shows potential for assessing biodiversity of coral reefs. Important steps in achieving this objective are better understanding the spectral variability of various reef components and correlating these spectral characteristics with field-based ecological assessments. Here we analyze >9400 coral reef field spectra from southwestern Puerto Rico to evaluate how spectral variability and, more specifically, spectral similarity between species influences estimates of biodiversity. Traditional field methods for estimating reef biodiversity using photoquadrats are also included to add ecological context to the spectral analysis. Results show that while many species can be distinguished using in situ field spectra, the addition of the overlying water column significantly reduces the ability to differentiate species, and even groups of species. This indicates that the ability to evaluate biodiversity with remote sensing decreases with increasing water depth. Due to the inherent spectral similarity amongst many species, including taxonomically dissimilar species, remote sensing underestimates biodiversity and represents the lower limit of actual species diversity. The overall implication is that coral reef ecologists using remote sensing need to consider the spatial and spectral context of the imagery, and remote sensing scientists analyzing biodiversity need to define confidence limits as a function of both water depth and the scale of information derived, e.g., species, groups of species, or community level.
Fullerene-Based Photoactive Layers for Heterojunction Solar Cells: Structure, Absorption Spectra and Charge Transfer Process
Authors: Li Yuanzuo , Qi Dawei , Song Peng , Ma Fengcai
Published: December 2014

The electronic structure and optical absorption spectra of polymer APFO3, [70]PCBM/APFO3 and [60]PCBM/APFO3, were studied with density functional theory (DFT), and the vertical excitation energies were calculated within the framework of the time-dependent DFT (TD-DFT). Visualized charge difference density analysis can be used to label the charge density redistribution for individual fullerene and fullerene/polymer complexes. The results of current work indicate that there is a difference between [60]PCBM and [70]PCBM, and a new charge transfer process is observed. Meanwhile, for the fullerene/polymer complex, all calculations of the twenty excited states were analyzed to reveal all possible charge transfer processes in depth. We also estimated the electronic coupling matrix, reorganization and Gibbs free energy to further calculate the rates of the charge transfer and the recombination. Our results give a clear picture of the structure, absorption spectra, charge transfer (CT) process and its influencing factors, and provide a theoretical guideline for designing further photoactive layers of solar cells.
Intestinal Absorption of Fucoidan Extracted from the Brown Seaweed, Cladosiphon okamuranus
Authors: Nagamine Takeaki , Nakazato Kyoumi , Tomioka Satoru , Iha Masahiko , Nakajima Katsuyuki
Published: December 2014

The aim of this study was to examine the absorption of fucoidan through the intestinal tract. Fucoidan (0.1, 0.5, 1.0, 1.5 and 2.0 mg/mL) was added to Transwell inserts containing Caco-2 cells. The transport of fucoidan across Caco-2 cells increased in a dose-dependent manner up to 1.0 mg/mL. It reached a maximum after 1 h and then rapidly decreased. In another experiment, rats were fed standard chow containing 2% fucoidan for one or two weeks. Immunohistochemical staining revealed that fucoidan accumulated in jejunal epithelial cells, mononuclear cells in the jejunal lamina propria and sinusoidal non-parenchymal cells in the liver. Since we previously speculated that nitrosamine may enhance the intestinal absorption of fucoidan, its absorption was estimated in rats administered N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) in their drinking water. Rats were fed 0.2% fucoidan chow (BBN + 0.2% fucoidan rats), 2% fucoidan chow (BBN + 2% fucoidan rats) and standard chow for eight weeks. The uptake of fucoidan through the intestinal tract seemed to be low, but was measurable by our ELISA method. Fucoidan-positive cells were abundant in the small intestinal mucosa of BBN + 2% fucoidan rats. Most fucoidan-positive cells also stained positive for ED1, suggesting that fucoidan was incorporated into intestinal macrophages. The uptake of fucoidan by Kupffer cells was observed in the livers of BBN + 2% fucoidan rats. In conclusion, the absorption of fucoidan through the small intestine was demonstrated both in vivo and in vitro.
Augmenting Anti-Cancer Natural Products with a Small Molecule Adjuvant
Authors: Wahome Paul , Beauchesne Kevin , Pedone Anna , Cavanagh John , Melander Christian , Zimba Paul , Moeller Peter
Published: December 2014

Aquatic microbes produce diverse secondary metabolites with interesting biological activities. Cytotoxic metabolites have the potential to become lead compounds or drugs for cancer treatment. Many cytotoxic compounds, however, show undesirable toxicity at higher concentrations. Such undesirable activity may be reduced or eliminated by using lower doses of the cytotoxic compound in combination with another compound that modulates its activity. Here, we have examined the cytotoxicity of four microbial metabolites [ethyl N-(2-phenethyl) carbamate (NP-1), Euglenophycin, Anabaenopeptin, and Glycolipid 652] using three in vitro cell lines [human breast cancer cells (MCF-7), mouse neuroblastoma cells (N2a), and rat pituitary epithelial cells (GH4C1)]. The compounds showed variable cytotoxicity, with Euglenophycin displaying specificity for N2a cells. We have also examined the modulatory power of NP-1 on the cytotoxicity of the other three compounds and found that at a permissible concentration (125 µg/mL), NP-1 sensitized N2a and MCF-7 cells to Euglenophycin and Glycolipid 652 induced cytotoxicity.
Sulfated Galactofucan from the Brown Alga Saccharina latissima—Variability of Yield, Structural Composition and Bioactivity
Authors: Ehrig Karina , Alban Susanne
Published: December 2014

The fucose-containing sulfated polysaccharides (SP) from brown algae exhibit a wide range of bioactivities and are, therefore, considered promising candidates for health-supporting and medicinal applications. A critical issue is their availability in high, reproducible quality. The aim of the present study was to fractionate and characterize the SP extracted from Saccharina latissima (S.l.-SP) harvested from two marine habitats, the Baltic Sea and North Atlantic Ocean, in May, June and September. The fractionation of crude S.l.-SP by anion exchange chromatography including analytical investigations revealed that S.l.-SP is composed of a homogeneous fraction of sulfated galactofucan (SGF) and a mixture of low-sulfated, uronic acid and protein containing heteropolysaccharides. Furthermore, the results indicated that S.l. growing at an intertidal zone with high salinity harvested at the end of the growing period delivered the highest yield of S.l.-SP with SGF as the main fraction (67%). Its SGF had the highest degree of sulfation (0.81), fucose content (86.1%) and fucose/galactose ratio (7.8) and was most active (e.g., elastase inhibition: IC50 0.21 μg/mL). Thus, S.l. from the North Atlantic harvested in autumn proved to be more appropriate for the isolation of S.l.-SP than S.l. from the Baltic Sea and S.l. harvested in spring, respectively. In conclusion, this study demonstrated that habitat and harvest time of brown algae should be considered as factors influencing the yield as well as the composition and thus also the bioactivity of their SP.
The Effect of Mg Adding Order on the Liquid Structure and Solidified Microstructure of the Al-Si-Mg-P Alloy: An Experiment and ab Initio Study
Authors: Zhu Xiangzhen , Jiang Wei , Li Mingrui , Qiao Huan , Wu Yuying , Qin Jingyu , Liu Xiangfa
Published: December 2014

In this paper, the relationship between the liquid structure and the corresponding solidified microstructure of an Al-Si-Mg-P alloy was studied. Experimental results show that Mg can reduce the phosphorous-modification effect if it was added after adding Al-P alloy. However, when it is added before adding Al-P alloy, Mg has no effect on the phosphorous-modification. It is considered that the difference in liquid structure induced by changing the adding order of Mg should be responsible for the above phenomenon, and was investigated by ab initio molecular dynamics simulation (AIMD). It was believed that the high-active Mg atoms could bond P atoms to form P-Mg clusters and then reduce the modification effect of AlP, when pure Mg was added into the prepared Al-Si-P melt. When the pure Mg was added into Al-Si melt before adding Al-P alloy, the Mg atoms would be first occupied by Si atoms to form Mg-Si clusters, and thus lose the ability to eliminate P-Al clusters which dissolve into melt later, leading to a good phosphorous-modification effect.
Asperaculanes A and B, Two Sesquiterpenoids from the Fungus Aspergillus aculeatus
Authors: Gao Yu-Qi , Guo Chun-Jun , Zhang Qiang , Zhou Wen-Ming , Wang Clay , Gao Jin-Ming
Published: December 2014

Six sesquiterpenoids 1–6, including two new ones, an ent-daucane-type sesquiterpenoid, asperaculane A (1), and a nordaucane one, asperaculane B (2), and four known nordaucane derivatives, aculenes A–D 3–6, together with the known secalonic acid D (7), were isolated from a fermentation culture of the fungus Aspergillus aculeatus. Their structures and absolute configurations were established by analyses of their spectroscopic data, including 1D and 2D-NMR spectra, HR-ESIMS, electronic circular dichroism (ECD) data, and quantum chemical calculations. These metabolites were evaluated for in vitro cytotoxic activity against two cell lines, human cancer cell lines (HeLa) and one normal hamster cell line (CHO).
Synthesis, Characterization, and Mechanism of Formation of Janus-Like Nanoparticles of Tantalum Silicide-Silicon (TaSi2/Si)
Authors: Nomoev Andrey , Bardakhanov Sergey , Schreiber Makoto , Bazarova Dashima , Baldanov Boris , Romanov Nikolai
Published: December 2014

Metal-semiconductor Janus-like nanoparticles with the composition tantalum silicide-silicon (TaSi2/Si) were synthesized for the first time by means of an evaporation method utilizing a high-power electron beam. The composition of the synthesized particles were characterized using high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), selective area electron diffraction (SAED), and energy dispersive X-ray fluorescence (EDX) analysis. The system is compared to previously synthesized core-shell type particles in order to show possible differences responsible for the Janus-like structure forming instead of a core-shell architecture. It is proposed that the production of Janus-like as opposed to core-shell or monophase particles occurs due to the ability of Ta and Si to form compounds and the relative content of Ta and Si atoms in the produced vapour. Based on the results, a potential mechanism of formation for the TaSi2/Si nanoparticles is discussed.
A Novel Arch-Shape Nanogenerator Based on Piezoelectric and Triboelectric Mechanism for Mechanical Energy Harvesting
Authors: Xue Chenyang , Li Junyang , Zhang Qiang , Zhang Zhibo , Hai Zhenyin , Gao Libo , Feng Ruiting , Tang Jun , Liu Jun , Zhang Wendong , Sun Dong
Published: December 2014

A simple and cost-effective approach was developed to fabricate piezoelectric and triboelectric nanogenerator (P-TENG) with high electrical output. Additionally, pyramid micro structures fabricated atop a polydimethylsiloxane (PDMS) surface were employed to enhance the device performance. Furthermore, piezoelectric barium titanate (BT) nanoparticles and multiwalled carbon nanotube (MWCNT) were mixed in the PDMS film during the forming process. Meanwhile, the composition of the film was optimized to achieve output performance, and favorable toughness was achieved after thermal curing. An arch-shape ITO/PET electrode was attached to the upper side of the polarized composite film and an aluminum film was placed under it as the bottom electrode. With periodic external force at 20 Hz, electrical output of this P-TENG, reached a peak voltage of 22 V and current of 9 μA with a peak current density of 1.13 μA/cm2, which was six times that of the triboelectric generator without BT and MWCNT nanoparticles. The nanogenerator can be directly used to lighten 28 commercial light-emitting diodes (LEDs) without any energy storage unit or rectification circuit under human footfalls.
Accumulation of Phosphorus-Containing Compounds in Developing Seeds of Low-Phytate Pea (Pisum sativum L.) Mutants
Authors: Shunmugam Arun , Bock Cheryl , Arganosa Gene , Georges Fawzy , Gray Gordon , Warkentin Thomas
Published: December 2014

Low phytic acid (lpa) crops are low in phytic acid and high in inorganic phosphorus (Pi). In this study, two lpa pea genotypes, 1-150-81, 1-2347-144, and their progenitor CDC Bronco were grown in field trials for two years. The lpa genotypes were lower in IP6 and higher in Pi when compared to CDC Bronco. The total P concentration was similar in lpa genotypes and CDC Bronco throughout the seed development. The action of myo-inositol phosphate synthase (MIPS) (EC 5.5.1.4) is the first and rate-limiting step in the phytic acid biosynthesis pathway. Aiming at understanding the genetic basis of the lpa mutation in the pea, a 1530 bp open reading frame of MIPS was amplified from CDC Bronco and the lpa genotypes. Sequencing results showed no difference in coding sequence in MIPS between CDC Bronco and lpa genotypes. Transcription levels of MIPS were relatively lower at 49 days after flowering (DAF) than at 14 DAF for CDC Bronco and lpa lines. This study elucidated the rate and accumulation of phosphorus compounds in lpa genotypes. The data also demonstrated that mutation in MIPS was not responsible for the lpa trait in these pea lines.
Mathematical Modeling of Pro- and Anti-Inflammatory Signaling in Macrophages
Authors: Maiti Shreya , Dai Wei , Alaniz Robert , Hahn Juergen , Jayaraman Arul
Published: December 2014

Inflammation is a beneficial mechanism that is usually triggered by injury or infection and is designed to return the body to homeostasis. However, uncontrolled or sustained inflammation can be deleterious and has been shown to be involved in the etiology of several diseases, including inflammatory bowel disorder and asthma. Therefore, effective anti-inflammatory signaling is important in the maintenance of homeostasis in the body. However, the inter-play between pro- and anti-inflammatory signaling is not fully understood. In the present study, we develop a mathematical model to describe integrated pro- and anti-inflammatory signaling in macrophages. The model incorporates the feedback effects of de novo synthesized pro-inflammatory (tumor necrosis factor α; TNF-α) and anti-inflammatory (interleukin-10; IL-10) cytokines on the activation of the transcription factor nuclear factor κB (NF-κB) under continuous lipopolysaccharide (LPS) stimulation (mimicking bacterial infection). In the model, IL-10 upregulates its own production (positive feedback) and also downregulates TNF-α production through NF-κB (negative feedback). In addition, TNF-α upregulates its own production through NF-κB (positive feedback). Eight model parameters are selected for estimation involving sensitivity analysis and clustering techniques. We validate the mathematical model predictions by measuring phosphorylated NF-κB, de novo synthesized TNF-α and IL-10 in RAW 264.7 macrophages exposed to LPS. This integrated model represents a first step towards modeling the interaction between pro- and anti-inflammatory signaling.
Vision-Based Cooperative Pose Estimation for Localization in Multi-Robot Systems Equipped with RGB-D Cameras
Authors: Wang Xiaoqin , Şekercioğlu Y. , Drummond Tom
Published: December 2014

We present a new vision based cooperative pose estimation scheme for systems of mobile robots equipped with RGB-D cameras. We first model a multi-robot system as an edge-weighted graph. Then, based on this model, and by using the real-time color and depth data, the robots with shared field-of-views estimate their relative poses in pairwise. The system does not need the existence of a single common view shared by all robots, and it works in 3D scenes without any specific calibration pattern or landmark. The proposed scheme distributes working loads evenly in the system, hence it is scalable and the computing power of the participating robots is efficiently used. The performance and robustness were analyzed both on synthetic and experimental data in different environments over a range of system configurations with varying number of robots and poses.
Investigation of Slow-Moving Landslides from ALOS/PALSAR Images with TCPInSAR: A Case Study of Oso, USA
Authors: Sun Qian , Zhang Lei , Ding Xiaoli , Hu Jun , Liang Hongyu
Published: December 2014

Monitoring slope instability is of great significance for understanding landslide kinematics and, therefore, reducing the related geological hazards. In recent years, interferometric synthetic aperture radar (InSAR) has been widely applied to this end, especially thanks to the prompt evolution of multi-temporal InSAR (MTInSAR) algorithms. In this paper, temporarily-coherent point InSAR (TCPInSAR), a recently-developed MTInSAR technique, is employed to investigate the slow-moving landslides in Oso, U.S., with 13 ALOS/PALSAR images. Compared to other MTInSAR techniques, TCPInSAR can work well with a small amount of data and is immune to unwrapping errors. Furthermore, the severe orbital ramps emanated from the inaccurate determination of the ALOS satellite’s state vector can be jointly estimated by TCPInSAR, resulting in an exhaustive separation between the orbital errors and displacement signals. The TCPInSAR-derived deformation map indicates that the riverside slopes adjacent to the North Fork of the Stillaguamish River, where the 2014 mudslide occurred, were active during 2007 and 2011. Besides, Coal Mountain has been found to be experiencing slow-moving landslides with clear boundaries and considerable magnitudes. The Deer Creek River is also threatened by a potential landslide dam due to the creeps detected in a nearby slope. The slope instability information revealed in this study is helpful to deal with the landslide hazards in Oso.
Surface Freshwater Storage Variations in the Orinoco Floodplains Using Multi-Satellite Observations
Authors: Frappart Frédéric , Papa Fabrice , Malbeteau Yoann , León Juan , Ramillien Guillaume , Prigent Catherine , Seoane Lucía , Seyler Frédérique , Calmant Stéphane
Published: December 2014

Variations in surface water extent and storage are poorly characterized from regional to global scales. In this study, a multi-satellite approach is proposed to estimate the water stored in the floodplains of the Orinoco Basin at a monthly time-scale using remotely-sensed observations of surface water from the Global Inundation Extent Multi-Satellite (GIEMS) and stages from Envisat radar altimetry. Surface water storage variations over 2003–2007 exhibit large interannual variability and a strong seasonal signal, peaking during summer, and associated with the flood pulse. The volume of surface water storage in the Orinoco Basin was highly correlated with the river discharge at Ciudad Bolivar (R = 0.95), the closest station to the mouth where discharge was estimated, although discharge lagged one month behind storage. The correlation remained high (R = 0.73) after removing seasonal effects. Mean annual variations in surface water volume represented ~170 km3, contributing to ~45% of the Gravity Recovery and Climate Experiment (GRACE)-derived total water storage variations and representing ~13% of the total volume of water that flowed out of the Orinoco Basin to the Atlantic Ocean.
The Performances of MODIS-GPP and -ET Products in China and Their Sensitivity to Input Data (FPAR/LAI)
Authors: Liu Zhengjia , Shao Quanqin , Liu Jiyuan
Published: December 2014

The aims are to validate and assess the performances of MODIS gross primary production (MODIS-GPP) and evapotranspiration (MODIS-ET) products in China’s different land cover types and their sensitivity to remote sensing input data. In this study, MODIS-GPP and -ET are evaluated using flux derived/measured data from eight sites of ChinaFLUX. Results show that MODIS-GPP generally underestimates GPP (R2 is 0.58, bias is −6.7 gC/m2/8-day and RMSE is 19.4 gC/m2/8-day) at all sites and MODIS-ET overestimates ET (R2 is 0.36, bias is 6 mm/8-day and RMSE is 11 mm/8-day) when comparing with derived GPP and measured ET, respectively. For evergreen forests, MODIS-GPP gives a poor performance with R2 varying from 0.03 to 0.44; in contrast, MODIS-ET provides more reliable results. In croplands, MODIS-GPP can explain 80% of GPP variance, but it overestimates flux derived GPP in non-growing season and underestimates flux derived GPP in growing season; similar overestimations also presented in MODIS-ET. For grasslands and mixed forests, MODIS-GPP and -ET perform good estimating accuracy. By designing four experimental groups and taking GPP simulation as an example, we suggest that the maximum light use efficiency of croplands should be optimized, and the differences of meteorological data have little impact on GPP estimation, whereas remote sensing leaf area index/fraction of photo-synthetically active radiation (LAI/FPAR) can greatly affect GPP/ET estimations for all land cover types. Thus, accurate remote sensing parameters are important for achieving reliable estimations.
Spatio-Temporal Change of Snow Cover and Its Response to Climate over the Tibetan Plateau Based on an Improved Daily Cloud-Free Snow Cover Product
Authors: Wang Wei , Huang Xiaodong , Deng Jie , Xie Hongjie , Liang Tiangang
Published: December 2014

Using new, daily cloud-free snow-cover products, this study examines snow cover dynamics and their response to climate change. The results demonstrate that the daily cloud-free snow-cover products not only posses the advantages of the AMSR-E (unaffected by weather conditions) and MODIS (relatively higher resolution) products, but are also characterized by high snow and overall classification accuracies (~85% and ~98%, respectively), substantially greater than those of the existing daily snow-cover products for all sky conditions and very similar to, or even slightly greater than, those of the daily MODIS products for clear-sky conditions. Using the snow-cover products, we analyzed the snow cover dynamics over the Tibetan Plateau and determined that the maximum number of snow-covered days (SCD) in a year followed a decreasing tendency from 2003 to 2010, with a decrease in snow-covered area (SCA) equivalent to 55.3% of the total Tibetan Plateau area. There is also a slightly increasing tendency in the maximum snow cover area (SCA), and a slightly decreasing tendency in the persistent snow cover area (i.e., pixels of SCD > 350 days) was observed for the 8-year period, which was characterized by increases in temperature (0.09 °C/year) and in precipitation (0.26 mm/year). This suggests that, on the Tibetan Plateau, changes in temperature and precipitation exert a considerable influence on the regional SCD and SCA, as well as the distribution of persistent snow cover.
Modeling Forest Aboveground Biomass and Volume Using Airborne LiDAR Metrics and Forest Inventory and Analysis Data in the Pacific Northwest
Authors: Sheridan Ryan , Popescu Sorin , Gatziolis Demetrios , Morgan Cristine , Ku Nian-Wei
Published: December 2014

The United States Forest Service Forest Inventory and Analysis (FIA) Program provides a diverse selection of data used to assess the status of the nation’s forests using sample locations dispersed throughout the country. Airborne laser scanning (ALS) systems are capable of producing accurate measurements of individual tree dimensions and also possess the ability to characterize forest structure in three dimensions. This study investigates the potential of discrete return ALS data for modeling forest aboveground biomass (AGBM) and gross volume (gV) at FIA plot locations in the Malheur National Forest, eastern Oregon utilizing three analysis levels: (1) individual subplot (r = 7.32 m); (2) plot, comprising four clustered subplots; and (3) hectare plot (r = 56.42 m). A methodology for the creation of three point cloud-based airborne LiDAR metric sets is presented. Models for estimating AGBM and gV based on LiDAR-derived height metrics were built and validated utilizing FIA estimates of AGBM and gV derived using regional allometric equations. Simple linear regression models based on the plot-level analysis out performed subplot-level and hectare-level models, producing R2 values of 0.83 and 0.81 for AGBM and gV, utilizing mean height and the 90th height percentile as predictors, respectively. Similar results were found for multiple regression models, where plot-level analysis produced models with R2 values of 0.87 and 0.88 for AGBM and gV, utilizing multiple height percentile metrics as predictor variables. Results suggest that the current FIA plot design can be used with dense airborne LiDAR data to produce area-based estimates of AGBM and gV, and that the increased spatial scale of hectare plots may be inappropriate for modeling AGBM of gV unless exhaustive tree tallies are available. Overall, this study demonstrates that ALS data can be used to create models that describe the AGBM and gV of Pacific Northwest FIA plots and highlights the potential of estimates derived from ALS data to augment current FIA data collection procedures by providing a temporary intermediate estimation of AGBM and gV for plots with outdated field measurements.
CCS-DTN: Clustering and Network Coding-Based Efficient Routing in Social DTNs
Authors: Zhang Zhenjing , Ma Maode , Jin Zhigang
Published: December 2014

With the development of mobile Internet, wireless communication via mobile devices has become a hot research topic, which is typically in the form of Delay Tolerant Networks (DTNs). One critical issue in the development of DTNs is routing. Although there is a lot research work addressing routing issues in DTNs, they cannot produce an advanced solution to the comprehensive challenges since only one or two aspects (nodes’ movements, clustering, centricity and so on) are considered when the routing problem is handled. In view of these defects in the existing works, we propose a novel solution to address the routing issue in social DTNs. By this solution, mobile nodes are divided into different clusters. The scheme, Spray and Wait, is used for the intra-cluster communication while a new forwarding mechanism is designed for the inter-cluster version. In our solution, the characteristics of nodes and the relation between nodes are fully considered. The simulation results show that our proposed scheme can significantly improve the performance of the routing scheme in social DTNs.
Application of Wavelet Packet Entropy Flow Manifold Learning in Bearing Factory Inspection Using the Ultrasonic Technique
Authors: Chen Xiaoguang , Liu Dan , Xu Guanghua , Jiang Kuosheng , Liang Lin
Published: December 2014

For decades, bearing factory quality evaluation has been a key problem and the methods used are always static tests. This paper investigates the use of piezoelectric ultrasonic transducers (PUT) as dynamic diagnostic tools and a relevant signal classification technique, wavelet packet entropy (WPEntropy) flow manifold learning, for the evaluation of bearing factory quality. The data were analyzed using wavelet packet entropy (WPEntropy) flow manifold learning. The results showed that the ultrasonic technique with WPEntropy flow manifold learning was able to detect different types of defects on the bearing components. The test method and the proposed technique are described and the different signals are analyzed and discussed.
Modification of Graphene on Ultramicroelectrode Array and Its Application in Detection of Dissolved Oxygen
Authors: Wang Jinfen , Bian Chao , Tong Jianhua , Sun Jizhou , Li Yang , Hong Wen , Xia Shanhong
Published: December 2014

This paper investigated two different modification methods of graphene (GN) on ultramicroelectrode array (UMEA) and applied the GN modified UMEA for the determination of dissolved oxygen (DO). The UMEAs were fabricated by Micro Electro-Mechanical System (MEMS) technique and the radius of each ultramicroelectrode is 10 μm. GN-NH2 and GN-COOH were modified on UMEA by using self-assembling method. Compared with GN-NH2 modified UMEA, the GN-COOH modified UMEA showed better electrochemical reduction to DO, owing to better dispersing and more active sites. The GN-COOH on UMEA was electroreduced to reduced GN-COOH (rGN-COOH) to increase the conductivity and the catalysis performance. Finally, the palladium nanoparticles/rGN-COOH composite was incorporated into DO microsensor for the detection of DO.
Global Sustainability Accounting—Developing EXIOBASE for Multi-Regional Footprint Analysis
Authors: Wood Richard , Stadler Konstantin , Bulavskaya Tatyana , Lutter Stephan , Giljum Stefan , De Koning Arjan , Kuenen Jeroen , Schütz Helmut , Acosta-Fernández José , Usubiaga Arkaitz , Simas Moana , Ivanova Olga , Weinzettel Jan , Schmidt Jannick , Merciai Stefano , Tukker Arnold
Published: December 2014

Measuring progress towards sustainable development requires appropriate frameworks and databases. The System of Environmental-Economic Accounts (SEEA) is undergoing continuous refinement with these objectives in mind. In SEEA, there is a need for databases to encompass the global dimension of societal metabolism. In this paper, we focus on the latest effort to construct a global multi-regional input−output database (EXIOBASE) with a focus on environmentally relevant activities. The database and its broader analytical framework allows for the as yet most detailed insight into the production-related impacts and “footprints” of our consumption. We explore the methods used to arrive at the database, and some key relationships extracted from the database.
A Study on Electronic-Money Technology Using Near Field Communication
Authors: Jung Min
Published: December 2014

Recently, due to the introduction of NFC (Near Field Communication), it has become possible to make easy electronic payments. Therefore, a secure communication method is necessary in these environments. NFC can be said to be relatively safe compared to other communication methods, because it carries out communications within 10 cm. However, it has made possible the risk of impersonation attacks by a disguised reader, leaving user information on the reader. In order to solve these problems, in this paper, we propose an authentication scheme that can reduce the weight of computation by using only a hash function and XOR (eXclusive OR) operation algorithms. This paper also shows that our method is safe, since it leaves no information with the other party.