bluuebunny/crossref_metadata_2025 huggingface dataset:
External Quality Assurance Helps Improve Infrastructure for Testing Breast Biomarkers Across a Lower- and Middle-Income Country: Our Experience With Breast Biomarker Testing in the National Cancer Grid External Quality Assurance System in India
Authors: Shet Tanuja , Tambe Sonali , Phadatare Nitin , Panjwani Poonam , Desai Sangeeta , Sengar Manju , Pramesh C S
Published: December 2023

Context.—

Biomarkers in breast cancer need strict monitoring given their role in patient management.

Objective.—

To study the impact that regular participation in the National Cancer Grid (NCG) external quality assurance (EQA) system has on concordance rates for biomarkers in breast carcinoma.

Design.—

Tissue microarrays (TMAs) containing breast carcinomas were circulated to participating laboratories that performed immunohistochemistry for breast biomarkers. The returned TMAs were then assessed for test concordance.

Results.—

A total of 105 laboratories participated in the estrogen receptor (ER) and progesterone receptor (PR) EQA system cycles, and 99 centers participated in the human epidermal growth factor 2 (HER2) EQA system. In the ER EQA in the first cycle only 1 laboratory had a 100% concordance rate, which improved to 59 of 77 (76.6%) and 85 of 97 (87.6%) in the fourth and fifth cycles, respectively. In the PR EQA the 100% pass rate jumped from zero to 52 of 76 (68.4%) in the fourth cycle and 86 of 97 (88.6%) in the last cycle. For HER2 EQA, the 100% pass rates were seen in 7 of 23 laboratories (30.4%) in the first cycle, 49 of 78 laboratories (62.8%) in the fourth cycle, and 48 of 94 laboratories (51.1%) in fifth cycle of EQA. Centers that participated in the NCG EQA system for a longer period often changed testing methodology, with consequent improvement in their laboratory concordance rates. An increasing trend for the use of automated platforms and of the US Food and Drug Administration–approved antibody for HER2 testing was observed.

Conclusions.—

Our experience demonstrates that laboratory performance improves with participation in an EQA system even in less perfect settings, and this drives the placement of more proficient practices across the country.
Correction to: Correlation of Diffusion-weighted MR imaging and FDG PET/CT in the Diagnosis of Metastatic Lymph Nodes of Head and Neck Malignant Tumors
Authors: Şahin Şamil , Duymaz Yaşar Kemal , Erkmen Burak , Karabulut Burak , Deveci İldem , Sürmeli Mehmet , Şahin Yılmaz Aslı , Semiz Oysu Aslıhan , Oysu Çağatay
Published: December 2023

Correction to: Correlation of Diffusion-weighted MR imaging and FDG PET/CT in the Diagnosis of Metastatic Lymph Nodes of Head and Neck Malignant Tumors
https://doi.org/10.58600/eurjther.20232902-450.y
 
The original version of this article [1], unfortunately contained an error. The name of Aslıhan Semiz Oysu, who is one of the co-authors and took part in every stage of the study, was not inadvertently added to the author list by the corresponding author. The author apologizes for this confusion. Given in this article are the correct author names.
 
Publisher's Note: The original article was corrected, and a correction note was added.
 
Şahin Ş, Duymaz YK, Erkmen B, Karabulut B, Deveci İ, Sürmeli M, Şahin Yılmaz A, Semiz Oysu A, Oysu Ç (2023) Correlation of Diffusion-weighted MR imaging and FDG PET/CT in the Diagnosis of Metastatic Lymph Nodes of Head and Neck Malignant Tumors. Eur J Ther. 29(2):135-142. https://doi.org/10.58600/eurjther.20232902-450.y
ANALYZING THE CONCEPT OF MINORITY INFLUENCE IN GROUP DECISION MAKING THROUGH “12 ANGRY MEN” FILM
Authors: KAPTAN Zeynep
Published: December 2023

The aim of this study is to examine the group dynamics and decision-making process in the movie "12 Angry Men" with a micro-level critical discourse analysis. The study aims to explore the influence of a member within the group on collective decisions and the influence of the first advocate of face-to-face group discussion. The leadership behavior of Henry, the main character of the movie, influences the group despite being in a minority position, and provides a platform for discussion. By tackling different topics, Henry creates differences of opinion among the majority, thereby understanding the thinking of each member and shaping their speech. Henry's position in the group can be explained by his minority influence; because in the beginning only he did not comply with the majority by voting "not guilty". However, he later acted consistently in his decision, causing the group's thoughts and votes to change. This study provides an important example for understanding the complexity of group dynamics and communication and highlights the role of leadership in minority influence.
Karaçam (Pinus nigra Arnold.) Meşcerelerinde Yıllık İbre Döküm Miktarı ve Bu Yolla Ekosisteme Geri Dönen Karbon ve Azot’un Tespiti
Authors: ÇAKIR Meriç , SARGINCI Murat , AKBURAK Serdar
Published: December 2023

Orman ekosistemlerinde, ibre döküm miktarı;

ekosistem fonksiyonlarından birincil üretim, karbon

ve besin maddelerinin döngüleri ile küresel iklim

değişikliğini de kapsayan önemli süreçler hakkında

bilgiler sunmaktadır. Araştırma Ormanı’nda

(Çankırı) yürütülen bu çalışmanın amacı yarı kurak

bölgede yer alan bazı karaçam meşcerelerinde ibre

dökümü ve bu yol ile ekosisteme geri dönen karbon

(C) ve azot (N) miktarlarının belirlenmesidir. Farklı

gelişim çağlarındaki karaçam meşcerelerinde

ortalama ibre döküm miktarları Çkab: Çkb ve Çkc

meşcereleri için sırasıyla 474,72 g.m-2, 245,51 g.m-2

ve 248,42 g.m-2 olarak bulunmuştur. Dökülen bu

ibrelerdeki karbon, Çkab, Çkb ve Çkc meşcereleri

için sırasıyla 251 g.m-2, 129 g.m-2 ve 130 g.m-2 olarak

belirlenirken, ibrelerdeki azot sırasıyla 8,15 g.m-2,

4,85 g.m-2 ve 4,73 g.m-2 olarak belirlenmiştir.

Tekrarlanan ölçümlerdeki varyans analizi sonuçlarına

göre Çkb ve Çkc meşcereleri arasında fark

bulunmazken (P>0,05), ibre dökümü, karbon ve azot

miktarları (g.m-2) Çka meşceresinde diğer iki

meşcereye kıyasla yüksek bulunmuştur (P
The Limits of Data
Authors: Nguyen C. Thi
Published: December 2023

Data is powerful because it’s universal. The cost is context.
Does Artificial Intelligence have the Possibility of Taking Over Designers' Jobs in the Future?
Authors:   Department of Architecture, Leading University (LU) Sylhet, Bangladesh., Hoque Farhana
Published: December 2023

Technological advances in tools such as artificial intelligence have made it easier for architects, planners, interior designers and urban designers to visualize their designs easily and save time. Today, AI (Artificial Intelligence) is integrated into many different professions, and the design sector is no exception. Also, new design technologies, for example, OpenAI, ChatGPT, Dall-E 2, and Mid Journey, quickly dissolve the lines between what humans do at work and what machines and algorithms do. Despite the fact that design is a highly creative discipline that calls for a special blend of technical expertise, aesthetic judgment, and user empathy, AI systems are currently unable to fully recreate these skills. They only provide output in accordance with system input. They are unable to independently innovate new things. And indeed, we discovered that AI fundamentally alters the practice of design. Traditional problem-solving tasks performed by designers are increasingly computerized into unrestricted volume and speed learning loops. This situation raises the question of whether artificial intelligence will replace the job of designers in the future. This essay would attempt to give an explanation of two factors, first, how AI technology would mitigate designers’ duties, and second, the reasons why it would not be able to replace designers and architects in the near future. The article seeks to do a discourse, summarizing the studies on the effects of AI on the professional activity of designers and projecting where future designers will stand in their respective fields. Furthermore, this paper discusses the implications of artificial intelligence on the profession of designers, such as job displacement, job redefinition, and changes in the skill set required to be successful in the profession. Finally, the outcome of the essay is to understand the revolutionary impact of AI tools in design sectors in the future.
Tinjauan Yuridis Faktor Pemicu Dan Pendekatan Intervensi Tawuran Remaja Di Bandar Lampung
Authors: Edo Arya Prabowo  , Lucky Arijano Augusta Putra  , Angga Alfiyan
Published: December 2023

This research investigates the phenomenon of juvenile brawls with a focus on analyzing trigger factors and developing effective intervention approaches. Involving field research and psychological analysis, this research identifies that interpersonal conflict in the context of schools and urban communities plays a crucial role in triggering brawls. Factors such as economic strain, academic pressure, and lack of interpersonal understanding among teenagers stand out as major triggers. Apart from that, the influence of pop culture and the social environment also contributes significantly to the increase in brawl incidents. This research presents recommendations for developing preventive programs that involve collaboration between schools, families and communities. A holistic intervention approach, including psychological and social aspects, was identified as key to reducing and preventing youth brawls. It is hoped that this research can provide valuable insights for practitioners, researchers and policy makers in creating a safe and supportive environment for adolescent development.
Акустические свойства кристаллов
Authors:   Samarqand davlat universiteti, Ф.Р Ахмеджанов
Published: December 2023

Исследована зависимость скорости, эффективных упругих констант и
затухания акустических волн от концентрации брома в кристаллах твердых растворов NaClNaBr. Показано, что эффективные упругие константы вдоль направления [100] изменяются
линейно при изменении состава твердого раствора при комнатной температуре. Максимальное
изменение этих величин в диапазоне концентраций от 6 до 30 моль% не превышает 10-15%.
Обнаружено также сильное до 70% уменьшение затухания продольных и поперечных
акустических волн, которое объясняется уменьшением времени фононной релаксации и
уменьшением эффективной константы ангармонизма
PENGARUH KUALITAS AKRUAL, LEVERAGE, UKURAN PERUSAHAAN DAN ARUS KAS TERHADAP CASH HOLDING PERUSAHAAN
Authors: Anjelina Ragilia , Suhendra Chairul
Published: December 2023

The population in this study are manufacturing companies listed on the Indonesia Stock Exchange in 2019-2021, totaling 72 companies. The sample used in this study amounted to 19 companies using a purposive sampling technique. The data analysis technique used is the Classical Assumption Test and Partial Hypothesis Test (T Test) and Simultaneous (F Test) with the help of the SPSS 22 Program. The results of this study show partially Accrual quality (X1) has no effect on the company's cash holding with a significant value of 0.248> 0.05 (5%), Leverage (X2) has an effect on the company's cash holding with a significant value of 0.034 <0.05, Firm size (X3) has an effect on the company's cash holding with a significant value of significant 0.000 <0.05, Cash Flow (X4) has no effect on the company's cash holding with a significant value of 0.654> 0.05 (5%). While simultaneously Accrual Quality, Leverage, Company Size, and Cash Flow have a joint effect on the company's cash holding with a significant value of 0.000 <0.05 (5%).
PENGARUH AUDIT TENURE, KOMITE AUDIT DAN AUDIT CAPACITY STRESS TERHADAP KUALITAS AUDIT (Perusahaan Manufaktur yang terdaftar di BEI Priode 2019-2021)
Authors: Asmarani Indah , Hernadianto Hernadianto
Published: December 2023

Kualitas audit digunakan untuk meningkatkan kredibilitas laporan keuangan pengguna informasi akuntansi sehingga dapat mengurangi risiko informasi keuangan yang tidak kredibel dalam laporan keuangan bagi pengguna laporan keuangan. Tujuan penelitian adalah untuk mengetahui sejauh mana komponen auditing yang terdiri dari audit tenure, komite audit dan audit capacity stress berpengaruh terhadap kualitas audit. Penelitian ini merupakan penelitian kausatif, sampel adalah perusahaan manufaktur sub sektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) tahun 2019-2021, dengan teknik purposive sampling didapat sebanyak 30 perusahaan memenuhi kriteria. Pengumpulan data menggunakan teknik dokumentasi, laporan tahunan dari situs perusahaan, situs Bursa Efek Indonesia https://www.idx.co.id dan situs https://sikap.bpk.go.id/. Analisis data menggunakan model Regresi Logistik Biner, uji determinasi dan uji hipotesis. Hasil penelitian diketahui bahwa terdapat pengaruh yang signifikan dan negatif antara audit tenure terhadap kualitas audit dengan perbandingan signifikansi 0,047 < 0,05 dan koefisien sebesar -0,023. Terdapat pengaruh yang signifikan dan positif antara komite audit terhadap kualitas audit dengan perbandingan signifikansi 0,001 < 0,05 dan koefisien regresi sebesar 0,907. Terdapat pengaruh yang signifikan dan negatif antara audit capacity stress terhadap kualitas audit dengan perbandingan signifikansi 0,000 < 0,05 dan koefisien regresi sebesar -0,994. Terdapat pengaruh audit tenure, komite audit dan audit capacity stress, secara bersama-sama terhadap kualitas audit dengan perbandingan signifikansi 0,000 < 0,05. Diketahui bahwa audite tenure, komite audit dan audit capacity hanya menjelaskan sebesar 30% pengaruhnya terhadap kualitas audit dan sisanya sebesar 70% dijelaskan oleh variabel lain yang tidak dimasukkan dalam model ini. Oleh sebab itu, disarankan kepada peneliti selanjutnya untuk menguji variabel lain yang dapat berpengaruh terhadap kualitas audit, seperti rotasi KAP, biaya audit, dan lainnya..
CHALLENGES OF INCLUSION FROM THE PERSPECTIVE OF PARENTS AND EDUCATIONAL WORKERS
Authors:   Herzegovina University, Mujkanović Elvira
Published: December 2023

The inclusion of children with developmental disabilities in the regular educational system is a process that is being developed and perfected. Accepting diversity and understanding the difference cannot be changed in a short time. It is an ongoing process, and it takes a lot of effort and time to achieve good results. When all actors of the inclusive process have similar views on inclusion, then we will be able to talk about acceptance, understanding and its successful implementation. Informing and educating students, teachers, and parents of children without disabilities is a good basis for developing inclusion and an inclusive society. Within the project "Educational - rehabilitation support for children with disabilities in inclusion", members of the Association for Support of Children with Developmental Disabilities "LALA" carried out workshops and lectures for students, parents and teachers. The goal of the project was to provide support to children with developmental disabilities, parents of children with developmental disabilities, as well as teachers in order to make the educational process as successful as possible for all actors of the inclusive process. After the workshops and lectures, we examined the views of parents of children with developmental disabilities and educators about inclusion and the challenges they most often face. The results of the research showed that both sides share the opinion that it is necessary to permanently work on information, education and communication between all actors of the inclusive process of upbringing and education with the aim of building an inclusive society.
Primer reporte nacional de las plagas asociadas a la lechuguilla Agave lechuguilla, Torrey.
Authors: Flores Flores Jorge David , Perales G José Ma
Published: December 2023

El presente estudio es una modesta aportación al estudio de las plagas asociadas a la lechuguilla Agave lechuguilla, aunque al parecer, pudiera ser éste el primer reporte nacional que se haga sobre este recurso. 

El trabajo se realizó en siete ejidos ixtleros del sur de Coahuila, utilizando un método de muestreo denominado de selección controlada, en sitios permanentes de muestreo. 

Las plagas de mayor importancia que se reportan en el estudio son: el perforador de las hojas Peltophorus polymitus, el barrenador del cogollo Megathymus sp y el barrenador del amole Scyphophorus interstitialis. Además, se reportan escamas, chapulines, esqueletizadores, roedores, lagomorfos, y un gusano de la familia Noctuidae que ataca la floración. Finalmente, se discute el impacto económico que tienen estas plagas en la producción de fibra de lechuguilla.
Performance of wheat (Triticum aestivum) varieties under different sowing dates and nitrogen levels in the sub montane region of Punjab
Authors: VIRENDER SARDANA  , S.K. SHARMA  , A.s. RANDHAWA
Published: December 2023

The effect of sowing time and nitrogen application on some newly developed varieties of wheat (Triticum aestivum L. emend. Fiori. Paol). was studied at Gurdaspur, on sandy loam soil conditions of sub montane region of Punjab during winters of 1997 98 to 1999 2000. Sowing time significantly influenced the growth, yield attributes, grain and straw yields in all the years. Delay in sowing from 15 November to 15 December decreased the wheat grain yield by 32.6 and 27.4% in 1997 98 and 1998 99, respectively, with mean reduction of 45 kg grainlhalday. Nitrogen application up to 150 kglha improved various yield attri6utes and increased the grain yield in both years, with mean increase of 7.4% over 120 and 13.9 % over 90 kg Ntha. Varieties also differed significantly. The maximum grain yield was registered in PBW 343, whereas HD 2329 gave the minimum grain yield. PBW 343 and HD 2687 gave comparable yields when sown on 15 November whereas in case off 15 December sowing, PBW 343 gave significantly higher grain yield than all other varieties. PBW 343 also gave significantly higher yield than WH 542 and HD 2329 at 150 kg Nlha and all varieties at lower levels of nitrogen.
La importancia del correcto uso de las fórmulas de estimación de la composición corporal
Authors: Morales Rodriguez Isabel , Soto Voisier Estefanía , Sepúlveda Schroder Cristián , Bertoglia Ghiglino Carla
Published: December 2023

En los últimos años, ha habido un aumento en los cursos de certificación ISAK a nivel nacional, lo que ha llevado a un incremento en el número de antropometristas certificados.
ISAK es una organización que busca estandarizar las mediciones antropométricas corporales. En 2022, se lanzó el software ISAK METRY, que permite estimar la composición corporal utilizando el modelo de 5 componentes propuesto por Deborah Kerr en 1988. Sin embargo, existe una discrepancia en la medición del perímetro de muslo utilizado en el software en comparación con el estudio original de Kerr.
Esto es relevante ya que puede afectar la comparabilidad de los datos generados por ISAK METRY con otros estudios que utilizan el modelo penta-compartimental. Se insta a los profesionales y formadores en antropometría a considerar esta discrepancia para evitar errores que puedan afectar negativamente la colaboración, la investigación y la toma de decisiones en el ámbito deportivo.
Association between Left Ventricular Longitudinal Strain (GLS) and Prognosis of the Patients Undergoing Heart Valve Surgery with Preserved Left Ventricular Ejection Fraction
Authors: Xue Yin-Ying , Chen Shang-Yu , Xiao Ji-Lai , Shen Xiao , Xu Huan , Hong Liang , Song Xiao-Chun , Zhang Cui
Published: December 2023

Purpose: Global longitudinal strain (GLS) seems accurate for detecting subclinical myocardial dysfunction. This study aimed to determine the association between GLS and postoperative intensity of inotropic support in the patients undergoing heart valve surgery with preserved left ventricular ejection fraction. Methods: 74 patients with preserved left ventricular ejection fraction who underwent valve surgery during the period between March 2021 and June 2022 were included in this prospective observational study. Transthoracic echocardiography including strain analysis with speckle tracking was performed before surgery. Patients were stratified according to the left ventricle (LV) GLS: LV-GLS ≥–16% (Impaired GLS group) and LV-GLS <–16% (Normal GLS group). The primary endpoint was postoperative vasoactive inotropic score. A high vasoactive inotropic score (VIS) was defined as a maximum VIS of ≥15 within 24 hours postoperatively. Postoperative adverse events, baseline clinical and echocardiographic data were also recorded. We invested the ability of preoperative GLS in predicting adverse postoperative outcomes, such as prolonged mechanical ventilation and the need for pharmacologic hemodynamic support after cardiac surgery. Results: Seventy-four patients were included and analyzed in this study, including thirty-three in impaired GLS group and forty-one in normal GLS group. In-hospital mortality was 1.27% (1/74). Patients in impaired GLS group were more likely to have prolonged mechanical ventilation (p = 0.041). Multivariable logistic regression analysis revealed that the apical four-chamber view of the left ventricle (A4C)-GLS was significantly associated with high VIS (OR 1.373, p = 0.007). A4C-GLS had a sensitivity of 62.5% and a specificity of 89.66% for predicting high VIS (area under the curve, 0.78). The relationships between GLS and other secondary outcome measures were not statistically significant. The optimal cutoff of A4C-GLS for postoperative high vasoactive inotropic score was –10.85%. Conclusion: Preoperative LV dysfunction is an independent risk factor for postoperative high VIS. A4C-GLS may be a reliable tool in predicting high VIS after cardiac surgery. Those patients with impaired contractility were at high risk for elevated inotropic support and prolonged mechanical ventilation after cardiac surgery. These findings suggest an important role for echocardiographic GLS in perioperative assessment of cardiac function in the patients undergoing cardiac surgery.
Development and Validation of a Novel Nomogram for Predicting Perioperative Acute Kidney Injury Following Isolated Off-Pump Coronary Artery Bypass Grafting Surgery
Authors: Shoulei Chen  , Cheng Luo  , Chen Fang  , Yugui Li  , Xiongwei Cai  , Guoxing Ling  , Haitao Song  , Sida Fan  , Linsheng Mi  , Sai Zheng  , Baoshi Zheng
Published: December 2023

Background: The aim of this work was to create a novel model for predicting acute kidney injury (AKI) after off-pump coronary artery bypass graft (OPCABG). Methods: The individuals who underwent OPCABG were randomly separated into a derivation group and a validation group, at a 7:3 ratio. The primary outcome was AKI under the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. To optimize feature selection and construct a nomogram, both least absolute shrinkage and selection operator regression (LASSO) and logistic regression analysis were utilized. The nomogram was assessed in various ways: with the C-index, calibration curve, decision curve analysis (DCA), and clinical impact curve analysis (CICA). Results: The use of an intra-aortic balloon pump (IABP), systolic blood pressure, smoking and baseline serum creatinine were identified as independent impact factors. The C-index of the nomogram was 0.733 (95% confidence interval (CI) = 0.669–0.791) and 0.786 (95% CI = 0.693–0.878) in the training and validation groups, respectively. The area under the curve (AUC) of the internal validation was 0.715 using bootstrapping with 1000 replicates. The calibration plot revealed that the predicted outcomes aligned well with the observations. DCA and CICA suggested that the model had clinical benefit. Conclusion: The nomogram that relied on clinical characteristics proved to be a dependable instrument to predict AKI after OPCABG. This model is conveniently applicable in clinical settings and will be a valuable resource for assessing timely medical measures to mitigate risk.
An Experimental Study on Modified Concrete Using Partial Replacement of Gravel and Admixtures
Authors: Lafta Yousif Jabbar , Mahdi Muthana Sh. , Al Menhosh Adel , Algusab Hussein Ali H.
Published: December 2023

Abstract: This study aims to test a concrete specimen with replacement partially of 15 % of the coarse aggregate by pieces of tires and volcanic aggregates and reduce 5% of the water/cement ratio by substituting with 4% percentages of styrene butadiene rubber (SBR) and 1% of superplasticizer. The main concrete components (cement: sand: gravel) were used in weight ratios (1:1.5:3) and a water to cement 0.45 was used and it was considered as a reference sample (Mix1). A water to cement ratio 0.40 was depended for the modified mixtures. Samples were cast for testing the compression strength with sizes 150 ×150 ×150 mm for ages 7 and 28 days. the absorption rate, with a size of 100 ×100 ×100 mm at age 28 days. Moreover, 150 ×150×150 mm for depth of penetration test at the age of 28 days.
Briefly, the observed results were exhibited that the partial replacement of normal aggregate in concrete with volcanic aggregate affects negatively on the workability, so 4% of the polymer SBR and 1% of the superplasticizer have improved the workability. The improvement in the workability of concrete contributed to reducing the ratio of water to cement required for mixing compared to ordinary concrete, and this in turn led to an improvement in performance of hardened concrete. In addition, the reduction of the permeability level. The results also illustrated that the replacement of the gravel in the modified mixtures (Mix 3 and Mix 2) reduces the weight of hardened concrete by (10-12%) and (7-9%) compared with conventional concrete, respectively, which makes it suitable for use in mediumweight concrete applications.
Moreover, it can be concluded that the strength properties of the modified mix with volcanic aggregate improved by 19-20% compared to that of the unmodified concrete. While the modified concrete by cutting tires showed significant deterioration in the concrete's resistance 21% despite the reduction of concrete permeability.
Experiências de atuação gerontológicas em universidades de São Paulo e universidades abertas à terceira idade
Authors: Medeiros dos Santos Adriana Nancy , Garcia Zumkeller Mariana , Nascimento Ordonez Tiago
Published: December 2023

Pretende-se, neste artigo, apresentar duas experiências gerontológicas da atuação em uma universidade estadual e outra federal, ambas localizadas no estado de São Paulo, pontuando-se suas similaridades e diferenças. Assim, tornou-se possível a análise das possibilidades existentes para o bacharel em Gerontologia, para as pessoas idosas envolvidas com esse novo profissional, e vantagens para as instituições de ensino superior que dão oportunidade a esses profissionais oriundos de um curso interdisciplinar, com foco na gestão e qualificação dos serviços direcionados à terceira idade.
Capítulo 31: Coleoptera Linnaeus, 1758
Authors: Casari Sônia A. , Biffi Gabriel , Ide Sergio
Published: December 2023

Os membros da Ordem Coleoptera são conhecidos popularmente como besouros. Diferentes famílias são conhecidas por nomes populares particulares para cada região. Com distribuição cosmopolita, a ordem constitui o grupo maior e mais diverso de organismos do reino Animal, com cerca de 380 mil espécies descritas (Lawrence & Britton 1994; Ślipiński et al. 2011), que representam cerca de 35% do total de insetos. Em termos comparativos, o número de espécies de besouros excede o de plantas vasculares ou de fungos e é cerca de 90 vezes maior que o de mamíferos. São registradas cerca de 188 famílias no Mundo. No Brasil, já foram registradas pouco mais de 33 mil espécies em 115 famílias. Estima-se que o número real de espécies existentes esteja entre 1-12 milhões de espécies no mundo (Erwin 1982), com cerca de 130 mil no Brasil. O fator mais importante no sucesso de Coleoptera parece ser a evolução dos élitros, a forte esclerosação das partes expostas do corpo, presença de criptonefrídeos e especializações relacionadas a fitofagia. O principal efeito dessas estruturas está relacionado à proteção e a melhora nos mecanismos que reduzem a perda de água (Crowson 1981).
Capítulo 34: Mecoptera Packard, 1886
Authors: Machado Renato J. P. , Collucci Eliana
Published: December 2023

Os mecópteros não possuem nome popular no Brasil. A ordem é cosmopolita, ocorrendo em todas as regiões biogeográficas, exceto Antártica. Mecoptera compreende cerca de 740 espécies, distribuídas em nove famílias e 39 gêneros (Bicha 2018). A maioria das espécies ocorre em duas famílias, Panorpidae e Bittacidae, com cerca de 450 e 220 espécies respectivamente (Bicha 2018). A região Neotropical possui 77 espécies descritas, distribuídas em dez gêneros e quatro famílias: Bittacidae é a maior, com 72 espécies; Eomeropidae possui uma espécie, que ocorre no Chile. Meropeidae é representada também por uma espécie com registro somente para o Brasil (Machado et al. 2013) e Nannochoristidae com três espécies, encontradas na região Andina do Chile e da Argentina (Machado 2018). Para o Brasil, são registradas 26 espécies, 5 gêneros e duas famílias, Bittacidae e Meropeidae (Tab. 34.1) (Machado et al. 2009, 2013, 2018, 2022). Estima-se que o número real de espécies no mundo seja em torno de 1.200 e no Brasil, cerca de 100 espécies. A maioria das áreas da região Neotropical é subamostrada e as coletas são ocasionais, carecendo de uma padronização de metodologia. No Brasil, as regiões norte e sudeste são as mais bem amostradas.
The hydroecological characteristics of current state of the Zaporizhzhia (Dnipro) reservoir and its tributaries
Authors:   Oles Honchar Dnipro National University, Dnipro, Yesipova N. , Sharamok T. ,   Oles Honchar Dnipro National University, Dnipro, Sklyar T. ,   Oles Honchar Dnipro National University, Dnipro, Marenkov O. ,   Oles Honchar Dnipro National University, Dnipro, Gudym N. ,   Oles Honchar Dnipro National University, Dnipro, Foroshchuk V. ,   Fishing private enterprise «V.V. Foroshchuk», Dnipro
Published: December 2023

Purpose: to determine the hydroecological condition of the different areas of the Zaporizhzhia (Dnipro) reservoir and its tributaries (Samara River, Konoplyanka River), which are under technogenic pressure. Methodology: classical methods of determining hydrochemical indicators (pH, dissolved oxygen, carbon dioxide, permanganate oxidizability, anions and cations of organic and inorganic compounds) and microbiological parameters (total count of microorganisms and count of saprophytes) were used during the study. The content of heavy metals was determined by atomic absorption spectrophotometry. Findings: The study of the current hydroecological state of the Zaporizhzhia (Dnipro) reservoir in the summer period showed that, according to most parameters, the water quality did not exceed the MAC (maximum allowable concentration) for fish farming. The exception was the reduced oxygen dissolved concentration (by 10-25%) in almost all areas of the reservoir, and the high mineralization of water in the Samara Bay (2 MAC), due to the discharge of highly mineralized waters of the Samara River. In the long-term aspect, there is an increase in the total mineralization of the Samara River (4 MAC, which is under the influence of the discharge mine waters of the coal mining industry of Western Donbas. The analysis of the content of heavy metals in the reservoir indicated an increase in the concentration of copper - from 13 MAC in the Samara Bay to 21 MAC in the lower part of the reservoir. The Samara River was characterized by a high content of cadmium (1.5 MAC), copper (13 MAC), and nickel (2.3 MAC). Indicators of the ecological state of the Konoplyanka River had significant differences in its different areas: in the upper reaches of the river, where the economic and domestic effluents of the city of Kamianske and the tailings storage facilities for radioactive waste are located, water did not meet the MAC for oxygen content, carbon dioxide, nitrites, nitrates, mineral ions (Ca2+, Mg2+, Cl’, SO4-2), general mineralization and the count of saprophytic microorganisms; at the mouth of the river, exceeding the MAC for nitrate content and saprophytic microflora was recorded. Originality: data on the hydroecological state of the Zaporizhzhia (Dnipro) reservoir and its tributaries in the conditions of the war have been obtained. Practical value: the results of the conducted study can be used to develop a strategic program for the restoration of the ecosystem of the Dnipro reservoirs in the post-war period. Key words: Zaporizhzhia (Dnipro) reservoir, tributaries, hydrochemical parameters, count of microorganisms, heavy metals.
“CRIMES DE COLARINHO BRANCO” E CRIME INSTITUCIONALIZADO. COMARCA DE PORTO VELHO/RO.
Authors: Preczevski Edvino
Published: December 2023

A corrupção pública é um dos maiores problemas que afligem o Brasil e quando é realizada por grupos organizados, sendo, inclusive, institucionalizada, exige enfrentamento estatal estratégico e especializado. Este trabalho objetiva demonstrar como os Juízos Criminais da Comarca de Porto Velho, no Estado de Rondônia, vêm prestando a tutela jurisdicional nos chamados “crimes de colarinho branco” ou de corrupção em sentido amplo, especialmente os praticados por organizações criminosas arraigadas na plataforma oficial do Estado. Através de pesquisa em sistemas informatizados do Tribunal de Justiça do Estado de Rondônia e entrevistas realizadas com juízes, assessores de juízes e promotores de justiça, que atuam nas Varas Criminais Genéricas, da Comarca de Porto Velho, são apresentados os cenários que envolvem a prestação jurisdicional (diagnóstico da situação atual)e as dificuldades, bem como sugestões para reduzir os óbices e possibilitar uma atuação mais célere e eficaz, objetivando, principalmente, a recomposição do erário. A conclusão é que o caminho para superar a excessiva morosidade, nessa área, e melhorar a qualidade da prestação jurisdicional, a par de um melhor aparelhamento, é a especialização de um juízo, conforme já recomendou o Conselho Nacional de Justiça, através da Recomendação nº 03, de 30/05/2006, e observa-se noutros Estados da Federação (Mato Grosso, Pará, Bahia, Roraima, Alagoas, Rio de Janeiro e Santa Catarina) e também na esfera federal, nos Tribunais Regionais Federais da 2º e 5ª Regiões.
Evaluation of Periodontal Awareness, Attitudes and Behaviors Toward Oral and Dental Health of Patients Presenting to Bursa Oral and Dental Health Training and Research Hospital
Authors: AKPINAR Aysun
Published: December 2023

Periodontal diseases are inflammatory conditions that concern a large part of society and affect the hard and soft tissues around the teeth. These diseases can be treated easily and successfully when diagnosed at an early stage. The present research aimed to determine whether some sociodemographic factors affect periodontal health, reveal the factors that affect it, if any, and conduct studies to reduce the effects of these factors. To this end, a survey was conducted on 300 patients at Bursa Oral and Dental Health Training and Research Hospital to assess their periodontal health and awareness. This survey included questions about patients' oral and dental health, sociodemographic status, periodontal awareness, and examination frequency. The results obtained from the surveys were evaluated using the IBM SPSS Statistics program for statistical analysis. As a result of the statistical analysis, a significant relationship was found between gender, age, frequency of going to the dentist, educational status, frequency of tooth brushing, systemic diseases and smoking, and oral and dental health and periodontal awareness.
Algunos principios de diseño de espacios de ciencias de libre elección monotemáticos
Authors: Mateo González Ester , Sáez Bondía María José , Martín García Jorge , Fernández López del Moral Sara
Published: December 2023

Los espacios de ciencias de libre elección son afamados en las aulas de Educación Infantil debido a que pueden generar situaciones estimulantes que promueven aprendizajes científicos. En general, estos espacios abordan diversos temas de ciencias que se distribuyen en diferentes propuestas, de manera que en cada una de ellas se trate un tema. En este trabajo, en cambio, se presenta el diseño de cuatro espacios de ciencias de libre elección con la particularidad de que son monotemáticos, es decir, todas las propuestas que constituyen el espacio tratan un único tópico científico. Siguiendo el ciclo marcado por la Investigación Basada en el Diseño, tras su puesta en marcha en aulas de diferentes cursos de Educación Infantil y el análisis de las situaciones de aprendizaje provocadas, se establece una rúbrica de evaluación y algunos principios de diseño de estos espacios teniendo en cuenta el contexto, las preguntas que plantean las propuestas y la elección didáctica de los materiales.
Charles Bonn, Mounira Chatti, Naget Khadda (dir.) (2023). 'Le théâtre de genres dans l’œuvre de Mohammed Dib'
Authors: Luica Larissa Daiana
Published: December 2023

Récension du volume Le théâtre des genres dans l'oeuvre de Mohammed Dib paru en 2023 aux Presses Universitaires de Rennes sous la direction de Charles Bonn, Mounira Chatti et Naget Khadda.
Targeting Sex Determination to Suppress Mosquito Populations
Authors: Li Ming , Kandul Nikolay P. , Sun Ruichen , Yang Ting , Benetta Elena D. , Brogan Daniel J. , Antoshechkin Igor , Sánchez C. Héctor M. , Zhan Yinpeng , DeBeaubien Nicolas A. , Loh YuMin M. , Su Matthew P. , Montell Craig , Marshall John M. , Akbari Omar S.
Published: December 2023

Each year, hundreds of millions of people are infected with arboviruses such as dengue, yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious mosquito
Aedes aegypti
. Traditional control measures have proven insufficient, necessitating innovations. In response, here we generate a next generation CRISPR-based precision-guided sterile insect technique (pgSIT) for
Aedes aegypti
that disrupts genes essential for sex determination and fertility, producing predominantly sterile males that can be deployed at any life stage. Using mathematical models and empirical testing, we demonstrate that released pgSIT males can effectively compete with, suppress, and eliminate caged mosquito populations. This versatile species-specific platform has the potential for field deployment to effectively control wild populations of disease vectors.
Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions
Authors: Tiedje Kathryn E. , Zhan Qi , Ruybal-Pésantez Shazia , Tonkin-Hill Gerry , He Qixin , Tan Mun Hua , Argyropoulos Dionne C. , Deed Samantha L. , Ghansah Anita , Bangre Oscar , Oduro Abraham R. , Koram Kwadwo A. , Pascual Mercedes , Day Karen P.
Published: December 2023

Here we introduce a new endpoint “census population size” to evaluate the epidemiology and control of
Plasmodium falciparum
infections, where the parasite, rather than the infected human host, is the unit of measurement. To calculate census population size, we rely on a definition of parasite variation known as multiplicity of infection (MOI

var

), based on the hyper-diversity of the
var
multigene family. We present a Bayesian approach to estimate MOI

var

from sequencing and counting the number of unique DBLα tags (or DBLα types) of
var
genes, and derive from it census population size by summation of MOI

var

in the human population. We track changes in this parasite population size and structure through sequential malaria interventions by indoor residual spraying (IRS) and seasonal malaria chemoprevention (SMC) from 2012 to 2017 in an area of high-seasonal malaria transmission in northern Ghana. Following IRS, which reduced transmission intensity by > 90% and decreased parasite prevalence by ∼40-50%, significant reductions in
var
diversity, MOI

var

, and population size were observed in ∼2,000 humans across all ages. These changes, consistent with the loss of diverse parasite genomes, were short lived and 32-months after IRS was discontinued and SMC was introduced,
var
diversity and population size rebounded in all age groups except for the younger children (1-5 years) targeted by SMC. Despite major perturbations from IRS and SMC interventions, the parasite population remained very large and retained the
var
population genetic characteristics of a high-transmission system (high
var
diversity; low
var
repertoire similarity) demonstrating the resilience of
P. falciparum
to short-term interventions in high-burden countries of sub-Saharan Africa.
Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway
Authors: Ma Xin , Li Meng , Zhang Yuanyuan , Xu Tingting , Zhou Xinchen , Qian Mengqi , Yang Zhiren , Han Xinyan
Published: December 2023

As the largest mucosal surface, the gut has built a physical, chemical, microbial, and immune barrier to protect the body against pathogen invasion. The disturbance of gut microbiota aggravates pathogenic bacteria invasion and gut barrier injury. Fecal microbiota transplantation (FMT) is a promising treatment for microbiome-related disorders, where beneficial strain engraftment is a significant factor influencing FMT outcomes. The aim of this research was to explore the effect of FMT on antibiotic-induced microbiome-disordered (AIMD) models infected with enterotoxigenic Escherichia coli (ETEC). We used piglet, mouse, and intestinal organoid models to explore the protective effects and mechanisms of FMT on ETEC infection. The results showed that FMT regulated gut microbiota and enhanced the protection of AIMD piglets against ETEC K88 challenge, as demonstrated by reduced intestinal pathogen colonization and alleviated gut barrier injury. Akkermansia muciniphila (A. muciniphila) and Bacteroides fragilis (B. fragilis) were identified as two strains that may play key roles in FMT. We further investigated the alleviatory effects of these two strains on ETEC infection in the AIMD mice model, which revealed that A. muciniphila and B. fragilis relieved ETEC-induced intestinal inflammation by maintaining the proportion of Treg/Th17 cells and epithelial damage by moderately activating the Wnt/β-catenin signaling pathway, while the effect of A. muciniphila was better than B. fragilis. We, therefore, identified whether A. muciniphila protected against ETEC infection using basal-out and apical-out intestinal organoid models. A. muciniphila did protect the intestinal stem cells and stimulate the proliferation and differentiation of intestinal epithelium, and the protective effects of A. muciniphila were reversed by Wnt inhibitor. FMT alleviated ETEC-induced gut barrier injury and intestinal inflammation in the AIMD model. A. muciniphila was identified as a key strain in FMT to promote the proliferation and differentiation of intestinal stem cells by mediating the Wnt/β-catenin signaling pathway.
Akkermansia muciniphila identified as key strain to function in pathogen invasion and intestinal stem cell proliferation through Wnt signaling pathway
Authors: Ma Xin , Li Meng , Xu Tingting , Zhou Xinchen , Qian Mengqi , Yang Zhiren , Cao Kai , Han Xinyan
Published: December 2023

As the largest mucosal surface, the gut has built a physical, chemical, microbial and immune barrier to protect the body against pathogen invasion. The disturbance of gut microbiota aggravates pathogenic bacteria invasion and gut barrier injury. Fecal microbiota transplantation (FMT) is a promising treatment for microbiome-related disorders, where probiotic strain engraftment is a significant factor influencing FMT outcomes. The aim of this research was to explore the effect of FMT on antibiotic-induced microbiome-disordered (AIMD) model infected with enterotoxigenic
Escherichia coli
(ETEC). We used piglet, mouse and intestinal organoid models to explore the protective effects and mechanisms of FMT on ETEC infection. The results showed that FMT regulated gut microbiota and enhanced the protection of AIMD piglets against ETEC K88 challenge, as demonstrated by reduced intestinal pathogen colonization and alleviated gut barrier injury.
Akkermansia muciniphila
(
A. muciniphila
) and
Bacteroides fragilis
(
B. fragilis
) were identified as two strains that may play key roles in FMT. We further investigated the alleviatory effects of these two strains on ETEC infection in AIMD mice model, which revealed that
A. muciniphila
and
B. fragilis
relieved ETEC-induced intestinal inflammation by maintaining the proportion of Treg/Th17 cells and epithelial damage by moderately activating the Wnt/β-catenin signaling pathway, while the effect of
A. muciniphila
was better than
B. fragilis
. We therefore identified whether
A. muciniphila
protected against ETEC infection using basal-out and apical-out intestinal organoid models.
A. muciniphila
did protect the Lgr5
+
intestinal stem cells and stimulate proliferation and differentiation of intestinal epithelium, and the protective effects of
A. muciniphila
was reversed by Wnt inhibitor. FMT alleviated ETEC-induced gut barrier injury and intestinal inflammation in AIMD model.
A. muciniph
ila was identified as key strain in FMT to promote proliferation and differentiation of intestinal stem cells by mediating the Wnt/β-catenin signaling pathway.
Instrumentos de caución para garantizar el fiel cumplimiento de los contratos administrativos: ¿existe una equivalencia funcional?
Authors: Colman Vega Luis
Published: December 2023

Esta investigación tiene como objetivo determinar si frente al incumplimiento del particular, resulta indiferente a la Administración la elección de la garantía de fiel cumplimiento de un contrato administrativo. En tal contexto, se analiza la realidad de la contratación administrativa y la forma en que interactúan con las cauciones, constatando que, pese a existir libertad de elección, se distinguen marcadamente ante el incumplimiento
Members’ willingness to pay for sustainability agricultural organization: A Heckman model approach
Authors: Topuz Bakiye Kilic
Published: December 2023

The purpose of this research analyzed the factors influencing the members’ willingness to pay capital in the agricultural cooperatives and unions. The research was performed on a sample 155 members of agricultural organizations in Igdir province of Türkiye using the Simple Random Sampling method. Members’ willingness to pay capital to their organizations were examined using the Contingent Valuation Method and effected factors were analyzed by Heckman Sample Selection model. The research showed that 56.6% of members were willing to pay capital an average of $131 for sustainability of organizations. According to the model results showed that members’ gender, agricultural income, know definition of organization, increase in income of members, pay entry capital, frequency of visiting, meeting the general assembly, cohesion of members positively affected, however, age, household, animal units, negative experience in the past with their organizations negatively affected the members’ willingness to pay capital. In order to sustainable of agricultural organizations, cohesion of members and participation to general assembly must increase. And, encouraging more young and female farmers to become a member, taking an active role cooperatives and unions in marketing and supply input could increase the members’ willingness to pay capital. In addition, training programs should be organized by agricultural organizations and government about increasing capital and economic participation.

Keywords: Agricultural organizations; Contingent analysis; Cooperative; Heckman sample selection model; Willingness to pay capital
Reflective Practices: Mixed Methods Research
Authors: Farr Fiona
Published: December 2023

Due to the complex, and often hidden, nature of reflective practice it is generally best researched through a mixed methods approach in order to provide as holistic and plausible an interpretation as possible. After a brief introduction to the origins and nature of reflective practice in the English language teaching profession, this entry provides a summary outline of five of the most commonly mixed research approaches in this field: linguistic ethnography, case study, narrative inquiry, discourse analysis, and action research. The teaching practice context is then chosen to illustrate good examples of previous mixed methods studies that have been published, with a final specific focus on teaching practice feedback as a stereotypical reflective practice in which pre‐ and in‐service teachers engage.