bluuebunny/crossref_metadata_2025 huggingface dataset:
Employee Engagement: Strategies for Reducing Turnover Intention at Mosque Marbot
Authors: Prima Jaya Fanlia , Wahab Abdul , Aspiannor Akhmad , Firdaus Wardhana Zainal
Published: February 2024

This study aims to obtain clarity about the Perceived Organizational profile Support and Work Life Balance profiles, turnover intention profiles, marbot Mosque employee engagement profiles, as well as obtaining clarity on the relationship between Perceived Organizational Support and Work Life Balance to turnover intentions through marbot masjid employee engagement. The research method used is the Explanatory Survey Method, the object of this research is all marbot Mosques in East Banjarmasin District, then a sample is drawn and gets as many as 63 respondents who are represented by each mosque in North Banjarmasin District. Analysis using Partial Least Square (PLS). The results showed that Perceived Organizational Support partially had a significant effect on employee engagement and turnover intention, Work life Balance partially had a significant effect on employee engagement and turnover intention, Perceived Organizational Support and Work life Balance simultaneously had a significant effect on turnover intention through employee engagement. The results of this study are important for takmir masjid and marbot masjid to understand and create a strong relationship between the two so that marbot masjid 's desire to move or stop working can be reduced.
Marketing Management of Educational Services in Improving The Image of Islamic Boarding Schools
Authors: Jannah Fillah Babul Fathatul , Hidayati Dian , Badrudin Badrudin
Published: February 2024

This research focuses on marketing management by Islamic boarding schools to improve their image. This study used a qualitative approach with six respondents who were then analyzed and assessed for the validity of the data using triangulation techniques at Islamic boarding schools in Bantul Regency. The results of the study show that: 1) the management of education service delivery at Islamic boarding schools has been running effectively, as evidenced by the increase in students every year; 2) factors that enhance the image of Islamic boarding schools include community support, the role of large foundations, and the commitment of Islamic boarding schools; 3) these factors are strengthened by the 4P concept of marketing mix strategy: product, promotion, process, and people; 4) media activities have an essential role during the marketing process; 5) special programs in Islamic boarding schools can also increase public interest; 6) the characteristics of each pesantren are the main attraction for the community's interest in pesantren. Furthermore, the image of the Islamic boarding school can be formed by implementing a marketing strategy by utilizing the marketing mix concept and can be built through good communication in every coordination.
The Influence of Internal Quality Assurance System on Quality Improvement of Accreditation in State Islamic Religious Universities Using The Technology Acceptance Model (TAM)
Authors: Hidayat Wahyu , Ardyanti Yefi , Wulan Elis Ratna
Published: February 2024

This study aims to analyze the effect of the internal quality assurance system on improving the accreditation quality of State Islamic Higher Education by using the Technology Acceptance Model (TAM). The research method used is quantitative. The research is an explanatory survey explaining the influence of the variables contained in the SPMI Information System in Higher Education. The research results show that; 1) There is a positive and significant effect of 62.4% both partially and simultaneously on all TAM variables on the use of the SPMI system; 2) There is a positive and significant effect of 53.5% both partially and simultaneously on all SPMI information system variables on improving the quality of accreditation. This research has implications for the importance of using other resources to improve the quality of education in tertiary institutions.
Efforts to Increase Lecturer Involvement through Organizational Culture, Transformational Leadership and Economic Prosperity
Authors: Pratiwi Sri Nurabdiah , Amini Amini
Published: February 2024

This study analyses efforts to increase lecturer involvement through organizational culture, transformational leadership and economic prosperity. The background of this research is located at STIT Al-Ittihadiyah Labuhanbatu Utara, North Sumatra Province. The research subjects included six lecturers, consisting of 4 permanent lecturers of the PGMI Study Program and two permanent lecturers of the PIAUD Study Program, as well as information from higher education leaders and the foundation. This study uses a qualitative approach to the type of case study. The results of this study conclude that the moral and direct involvement of private lecturers who teach at STIT Al-Ittihadiyah Labuhanbatu Utara increases from 2017 to 2022 based on 3 (three) aspects; the first is a conducive organizational culture based on integrity, professionalism and the principle of kinship. Second, the transformational leadership practised by high school leaders prioritizes the target of change rather than just a structural position. Third is economic welfare, where lecturers are given a monthly salary according to the number of teaching credits and salary allowances for permanent lecturers from the North Sumatra Al-Ittihadiyah educational foundation. The implications of this study show the importance of the role of leaders in stimulating the level of activeness of private university lecturers, so it is recommended for future researchers to analyze this variable in public universities, which have a higher level of lecturer welfare.Organizational Culture, Transformational Leadership, Lecturer Participation
The Influence of Teacher Performance, Commitment, and Professionalism on Student Learning Outcomes
Authors: Yuliansyah Muhammad , Herman Murdiansyah
Published: February 2024

This study aims to analyze the effect of teacher performance, commitment and professionalism on student learning outcomes at SMPN 14 Banjarmasin City. This type of research is quantitative research. The population used in this study were all teachers, namely 52 teachers. Sampling in this study is by saturation sampling. The data collection technique is using a questionnaire. Methods of data analysis using multiple linear regression with the IBM SPSS statistical 22 programs. The results showed that there is an effect of performance on student learning outcomes, there is an effect of commitment on student learning outcomes, there is a professional influence of teachers on student learning outcomes, there is a simultaneous effect on performance, teacher commitment and professionalism towards student learning outcomes at SMPN 14 Banjarmasin City.
Building Madrasah Committee Synergy in Managing Effective and Resilient Skills Programs
Authors: Suratman Suratman
Published: February 2024

This research focuses on marketing management by Islamic boarding schools to improve their image. This study used a qualitative approach with six respondents who were then analyzed and assessed for the validity of the data using triangulation techniques at Islamic boarding schools in Bantul Regency. The results of the study show that: 1) the management of education service delivery at Islamic boarding schools has been running effectively, as evidenced by the increase in students every year; 2) factors that enhance the image of Islamic boarding schools include community support, the role of large foundations, and the commitment of Islamic boarding schools; 3) these factors are strengthened by the 4P concept of marketing mix strategy: product, promotion, process, and people; 4) media activities have an essential role during the marketing process; 5) special programs in Islamic boarding schools can also increase public interest; 6) the characteristics of each pesantren are the main attraction for the community's interest in pesantren. Furthermore, the image of the Islamic boarding school can be formed by implementing a marketing strategy by utilizing the marketing mix concept and can be built through good communication in every coordination.
Women's Leadership in Creating Change, Synergy, and Empowering Human Resources in Madrasah
Authors: Junaidah Junaidah , Haryani Dwi , Fanisyah Elsah
Published: February 2024

Women's leaders have begun to play an active role in organizational activities in various fields, including education. Therefore, this study aims to analyze women's leadership in creating change, synergy and empowering existing human resources in madrasas using a descriptive and qualitative approach. This study used data collection techniques through interviews, observation, and documentation. Data analysis is divided into three current flows of activity: data reduction, data display, and concluding. According to the findings of this study, women leaders lead in several ways, including creating change by applying several principles of being open, insightful, and skilled; being disciplined, authoritative, and responsible; engaging in routine observation and discussion; and improving quality by participating in training. Furthermore, by creating synergy by applying the principle of cooperation and involving all human resources in decision-making that is consistent with decisions and policies, Then, in empowering human resources, women leaders apply the principles of assigning tasks and responsibilities according to competence, collaborating, granting autonomy, and facilitating human resources so that they are freer to develop themselves, especially those related to improving the quality of their learning activities. Based on these findings, this study is expected to serve as a model for women leaders to follow to become quality leaders.
Teacher Innovation through Knowledge Management and Personality Strengthening
Authors: Sukmanasa Elly , Novita Lina
Published: February 2024

This study aims to increase teacher innovation by examining knowledge management and personality relationships. The method used is a combination of correlation approaches and Sitorem analysis. There were 271 samples from a population of 1684 elementary school teachers with civil servant status using multistage proportional sampling. Data analysis comprised normality, homogeneity, linearity, and multiple regression tests. The study's results prove a solid or significant relationship between knowledge management and personality and teacher innovation, as indicated by the correlation coefficient ry123 = 0.652. SITOREM analysis shows that based on the order of priority, improvements that need to be increased include knowledge dissemination, awareness, openness, personal consideration, and business and organizational innovation. At the same time, the indicators that are maintained and developed are influence, product innovation, emotional stability, process innovation, inspirational motivation, application of knowledge, knowledge storage, agreeableness, service innovation, knowledge acquisition, intellectual stimulation, extraversion, and knowledge evaluating.
Optimizing The Prototype Curriculum Based on Religious Values and Local Wisdom through The Principal's Role
Authors: Saidek Abdul Rahim
Published: February 2024

This article aims to analyze the role of the principal in optimizing a prototype curriculum based on religious values and local wisdom in one of the Aliyah Negeri Madrasahs in Jambi Province. This study seeks to reveal the phenomena and meanings in the field, so the researcher uses a qualitative phenomenological approach to answer this. Observation, interviews and documentation were carried out to collect data in the field. While the data analysis was carried out in stages, starting from data collection, reduction, data display, and conclusion. The results of the study show that the role of the madrasa head in optimizing the prototype curriculum based on religious values and local wisdom is shown through; the head of the madrasa as a pioneer of reform, analyzing the needs of curriculum prototypes, curriculum design based on religious values and local wisdom, skills improvement, continuous monitoring and evaluation. This research provides implications for the importance of innovation, renewal, sensitivity and leadership strategic steps in responding to societal demands and the challenges of the times.
Challenges and Opportunities for Madrasah in Improving The Competence of Graduate Students
Authors: Putra Ali Musri Semjan , Siregar Kardina Engelina
Published: February 2024

This study aims to find out what madrasa strategies are in increasing the competence of graduate students in facing the globalization era at MAN 1 Pekanbaru and the factors that influence it. The informants in this study were school principals, curricula deputy heads, teachers and students of MAN 1 Pekanbaru. The madrasa strategy in increasing the competence of graduate students in facing the era of globalization at MAN 1 Pekanbaru is; 1) Changing the curriculum by adding material related to globalization; 2) Increasing the competence of teacher professionalism; 3) Changing the mindset of the teacher; 4) Improving the quality of madrasas; 5) Evaluate learning activities. Based on the results of observations, interviews, and documentation, it was found that the madrasah challenges were; 1) There is globalization; 2) Shifting educational paradigm; 3) Low public trust in madrasah productivity; 4) IT-based learning; 5) Curriculum changes; 6) Competence of madrasah graduates; 7) human resources produced by madrasas; 8) Network and collaboration of madrasah graduates.
Strategies for Overcoming Teacher Burnout in Schools; Expanding the Human Resource Management
Authors: Purnamaningsih Ine Rahayu
Published: February 2024

This study analyses human resource management in overcoming teacher burnout at SMA Negeri 1 Kota Cimahi. More and more demands from both the government and the institutions can lead to teacher burnout. This study uses a qualitative approach to the type of case study. The data was obtained from observation, interviews and documentation. The informants were selected through purposive sampling, resulting in 4 people: the principal, deputy head of curriculum, deputy head of student affairs, and subject teacher. The data analysis uses Yin's theory without any control, just observing and then explaining it. As for the results obtained, four stages in human resource management are implemented in SMA Negeri 1 Kota Cimahi: identifying, imitation, attention, and inference. Identifying is intended to recognize each character in their performance. Imitation is related to the principal's strategy in giving uswah to his subordinates. Attention is embodied in the principal's real action in involving teachers in all activities at school, and inference is related to concluding all the information collected from the initial stage to make a joint decision.
The Effect of Trust, Spirituality, and Interpersonal Communication on Organizational Citizenship Behaviour Certified Lecturer
Authors: Mansyur Mansyur , Akib Akib , Syahrul Syahrul
Published: February 2024

This article analyses the effect of Belief, Spirituality, and Interpersonal Communication on organizational citizenship behaviour (OCB). The research was conducted on seventy-two certified lecturers using path analysis. The results of the study show that there are direct and indirect effects of; 1) trust on the organizational citizenship behaviour of certified lecturers, 2) spirituality on the organizational citizenship behaviour of certified lecturers, 3) interpersonal communication on the organizational citizenship behaviour of certified lecturers; 4) belief in spirituality; 5) trust in interpersonal communication; 6) trust in organizational citizenship behaviour of certified lecturers through spirituality; 7) trust in organizational citizenship behaviour of certified lecturers through interpersonal communication. The results of this study confirm that high levels of trust, spirituality, and interpersonal communication influence any change in the organizational citizenship behaviour of certified lecturers. Therefore, these three variables must be considered in creating and improving the organizational citizenship behaviour of certified lecturers.
Learning Quality Improvement Management Model for Elementary School Teachers
Authors: Nisa Choirun , Khoirurrosyid Muhammad
Published: February 2024

This paper aims to describe; 1) the weaknesses and strengths of learning in SD Muhammadiyah based on the challenges of technological disruption, 2) the need for teachers to improve the quality of learning, 3) the management model for improving the quality of learning that is appropriate to be applied by teachers in schools. This study uses a Research & Development design containing three main elements: 1) development model, 2) development procedure, and 3) product trial design. The development procedure goes through three stages: 1) preliminary study, 2) model development, and 3) model testing. The research results found that; 1) the weaknesses and strengths of learning at Muhammadiyah Elementary School, namely the quality of teachers is still lacking, the evaluation implementation is minimal; the design has not been implemented, the learning process is still lacking, and students lack motivation. In contrast, IT-based learning in schools has yet to be implemented. 2) Improving the quality of schools requires proper management based on the needs and challenges of the school going forward; teachers need learning modules, classifying student subject matter according to potential, and participatory learning.
Charismatic Leadership and Silah Rituality in The Educational Culture of Boarding Schools
Authors: Akrim Akrim , Umiarso Umiarso
Published: February 2024

This research focuses on how to become a ritual in the communication process. This research is qualitative research with a phenomenological approach. The research participants comprised seven people: Kiai, ustadz and santri. Collecting research data using interviews and documentation and analysing with data reduction procedures, presentation and interpretation of data. The orientation should detail the role of rituality in charismatic leadership to build cultural commitment to education. After studying in-depth, it can be concluded that the company's charismatic leadership transforms spirituality in developing solidarity actions, work and religious commitment to Islamic boarding schools education. This research can be a reference for further research, focusing on studying Islamic boarding schools in Indonesia, especially on charismatic leadership patterns.
Principal Managerial Skills, Organizational Communication, Conflict Control, and Organizational Climate in Madrasah and Their Influence on Organizational Effectiveness
Authors: Salabi Ahmad
Published: February 2024

This research aims to analyze the relationship between school principals' managerial abilities, organizational communication, conflict control, and organizational climate with the organizational effectiveness of State Madrasah Aliyah in South Kalimantan Province. This research uses a quantitative approach with a survey method. Data was collected from 182 permanent teachers using proportional purposive sampling. The analysis was carried out using the SEM (Structural Equation Modeling) technique because this technique can be used to simultaneously answer regressive and dimensional problems. The LISREL (Linear Structure Relation) program version 8.30 was used as an analysis tool. Hypothesis test results show that: 1) The principal's managerial skills are directly related to organizational communication, conflict control, and organizational climate. 2) the principal's managerial skills indirectly relate to organizational effectiveness through conflict control and organizational climate as intervening variables. Organizational communication indirectly relates to organizational effectiveness through conflict control and organizational climate as intervening variables. Conflict control indirectly relates to organizational effectiveness through organizational climate as an intervening variable. This research provides implications regarding the importance of madrasah in taking concrete steps to increase the effectiveness of their organizations in achieving predetermined goals.
Financial Policy and Employee Behavior in Higher Education; The Planned Behaviour Approach with MARS Model
Authors: Syarifudin Syarifudin
Published: February 2024

This paper aims to analyze the impact of financial policies on employee behaviour at a university in East Kalimantan, which is analyzed using the theory of planned behaviour with MARS model. This study used a qualitative case study type approach, in which researchers used interviews, observation and documentation to obtain accurate information and data. Data analysis was carried out through data collection, data reduction, data display, and drawing conclusions. The results of the study show that transparent and accountable financial policies have a pretty good impact on the behaviour of the academic community at the Muhammadiyah University of Berau, starting from building good employee motivation, optimizing the implementation of the tri dharma of higher education, creating a sense of individual ownership of the organization and creating an excellent organizational culture. This research contributes to the importance of leaders in conducting their financial analysis appropriately and based on local wisdom so that the resulting policies will tremendously impact organizational progress.
Heutagogy Paradigm: Empowering Leadership Through Holistic Participatory Research in An Organization-Body
Authors: Hamdani Hamdani , Marzuki Marzuki , Mawardaniah Mawardaniah
Published: February 2024

This study examined the application of participatory action research to foster leadership qualities among middle-ranged members of the Muhammadiyah organization in Kota Langsa. Grounded in humanistic and constructivist principles, this approach seeks to unlock the potential traits of the organization's members. To achieve this objective, community-based participatory research (CBPR) of the participatory action research (PAR) design was employed, enabling active member participation and fostering improved leadership capabilities. The findings highlighted the significance of CBPR and the paradigm approach in validating members' experiences in leading, management, and organization. Through this study, the members have benefited themselves, their families, and the broader community for the paradigm nurture, contributing to personal and collective leadership characteristics. Therefore, the study contributes to the growing literature on empowering leadership development and showcases the efficacy of participatory research methodologies.
The Influence of Islamic Leadership, Religiosity, and Work Discipline with Work Ethic on Teacher Performance in Madrasah
Authors: Haekal T. M. , Wahidmurni Wahidmurni , Zuhriyah Indah Aminatuz
Published: February 2024

This research aims to find out the influence of Islamic leadership, religiosity, and work discipline with work ethic on teacher performance in State Madrasah Aliyah throughout Malang Raya. This research uses a quantitative approach with a correlational type. The population consisted of 224 teachers and 144 samples (simple random sampling) who were given a questionnaire. Data analysis using Smart PLS V.3.2.8. The research results found that Islamic leadership and religiosity positively and significantly affected teacher performance. In contrast, work discipline did not have a significant effect. Work ethic has a positive and significant influence on teacher performance. Although Islamic leadership does not directly influence teacher performance through work ethic, religiosity does not directly influence teacher performance through work ethic. Work discipline, although indirect, has a positive and significant impact on teacher performance through work ethic. In conclusion, certified teachers meet teacher performance standards in madrasas. This research has implications for the management and development of human resources in madrasas, especially in improving teacher performance, which should be carried out in a planned, systematic and sustainable manner through the total involvement of all parties.
Triggering Interest in Learning through Environmentally Based Space Management
Authors: Istifadah Istifadah , Usriyah Lailatul , Rahmawati Riyas
Published: February 2024

Interest in learning is still a classic problem teachers face in the learning process. The learning environment is one of the school resources that has the potential to arouse students' interest in learning. This research aims to explore and investigate how the design of the physical environment of classrooms or study rooms at the Alam Nurul Islamic School (SANI) Jember can influence students' interests. The research focus was analyzed using the theories of Tomkins, Renninger, Hidi, and several other relevant theories. This research uses a qualitative descriptive method, where data collection is carried out through observation, interviews, documentation, and photography. Data analysis uses the theories of Milles, Huberman, and Saldana with three steps, namely data condensation, data presentation, and verification. The SANI learning environment is managed with the nature-based school concept by utilizing and optimizing the characteristics of the school environment, such as context, content, and learning processes. In this research, strategies, and interventions in the planning and substance of natural environment-based space management by creating a natural learning environment infrastructure can increase students' motivation, attention, and learning experience and potentially increase student interest and engagement.
Investigating the Mediating Role of Organizational Commitment in the Relationship between Leadership, Motivation, Organizational Culture, and Work Discipline
Authors: Sukarji Sukarji
Published: February 2024

This research aims to determine and analyze the influence of leadership, motivation, and organizational culture on employee work discipline with organizational commitment as an intervening variable at MAN Tulungagung, East Java, Indonesia. The research method is quantitative with an explanatory research approach with a survey approach. Research data was taken from 79 teachers who were the sample for this research. This research analyzes data using multiple regression analysis. The results of the research show that 1) leadership has a significant effect on organizational commitment; 2) Organizational culture has a significant effect on organizational commitment; 3) Leadership has a significant effect on work discipline; 4) Organizational culture has a significant effect on work discipline; 5) Leadership has an indirect effect on work discipline through organizational commitment, which means there is a mediating influence. So, organizational commitment can mediate between organizational culture and work discipline. Organizational culture has an indirect effect on work discipline through organizational commitment, which means there is no mediating influence. So, organizational commitment cannot be a mediating variable between organizational culture and work discipline.
Follow the Leader: The European Commission, the European Court of Justice, and the EU’s Rule of Law Revolution
Authors: Mandujano Manriquez Mauricio , Pavone Tommaso
Published: February 2024

The autocratization of Hungary and Poland prompted a revolution in the European Court of Justice’s (ECJ) caselaw. The Court imposed novel obligations on member states to safeguard the rule of law (ROL) and expanded the legal bases for the EU to sanction governments. We ask: did the ECJ pioneer this ROL revolution or respond to an entrepreneurial European Commission acting as “guardian of the Treaties?” While supranationalist theories depict the Commission as a proactive agenda-setter, studies of the EU’s ROL crisis argue that the Commission dragged its feet or only recently seized the reins of leadership. Deploying a new theory of judicial innovation and agenda-setting on an original dataset of all ROL cases adjudicated by the ECJ, we demonstrate that the Commission has been an inconsistent and often indifferent agenda-setter. Besides several proactive interventions during the Juncker Commission, the Court’s rulings prompted the Commission to act more than the reverse.
Physicochemical properties of wild grown prickly pear fruits (Opuntia ficus-indica) in Yemen
Authors:   Department of Biotechnology and Food Technology, Faculty of Agriculture and Veterinary Medicine, Thamar University, Dhamar, Yemen., Alwaseai Amin Mohammed , Al-gabr Hamid Mohammed ,   Department of Life Science, Faculty of Education, Albaydha University, Albaydha.,Yemen.
Published: February 2024

This study aimed to estimate the physical and chemical properties of prickly pear fruits. Prickly pear fruit samples were collected from local markets in Dhamar, Yemen. The results showed that the mean weight of prickly pear fruits was 89.27 g, while the pulp, peel, seeds, and extracted juice weights were 47.57, 40.96, 3.52, and 37.07 g, respectively. The weight percentages of pulp, peel, seeds, and extracted juice were 53.72, 45.38, 3.79, and 34.85% of the fruit's weight, respectively. The chemical properties of prickly pear juice were: 86.83% moisture, 12.75 ˚brix total soluble solids, 13.17% total solids, 11.78% total sugars, 7.86% reducing sugar, 3.90% non-reducing sugar, 6.07 pH, 0.09% total acidity, and 28.41 mg/100 mL ascorbic acid content. The ˚brix/acidity ratio in prickly pear pulp extract was 178.87. These findings indicated that the prickly pear fruits that grow wild in Yemen possessed the majority of the desirable physicochemical properties, such as high soluble solids, low acidity, and a low seed content percentage, which make them marketable and exportable.
Alleviation of physiological traits in lemongrass under salinity stress
Authors:   Botany Department, Faculty of Science, Assiut University, Assiut 71511, Egypt, Salama Fawzy M. , Ragaey Marwa M. ,   Botany and Microbiology Department, Faculty of Science, New Valley University, El-Kharga, Egypt, Abdel-Rahman Sayed S. A. ,   Floriculture Department, Faculty of Agriculture, Assiut University, Assiut 71511, Egypt, Mostafa Noha M. M. ,   Medicinal and Aromatic Plants Department, Horticulture Research Inistitute, Agricultural Research Center, Giza, Egypt, Abd El-Kader Atef A.S. ,   Medicinal and Aromatic Plants Department, Horticulture Research Inistitute, Agricultural Research Center, Giza, Egypt
Published: February 2024

Lemongrass is considered one of the most economic medicinal and aromatic plants, and there is a tendency to expand the production of such important plants in newly reclaimed soils, which often suffer from salt stresses. There are natural and synthetic substances that can help plants resist stress. Therefore, this study was conducted for the purpose of using some natural substances, Moringa oleifera leaf extract (MLE), Bacillus subtilis + arbuscular mycorrhizal fungi (B+A), and synthetic substances, such as benzyl amino purine (BAP), on lemongrass plants exposed to salt stress imposed by irrigation at 0, 1000, 2000, and 4000 ppm levels. Results indicated that an increasing trend of carbohydrate content by growth stimulants was noticed as follows: Moringa leaf extract (MLE) >Bacillus subtilis + arbuscular mycorrhizal (B+M) > benzyl amino purine (BAP). Foliar application by growth stimulants increased free proline content. Application of MLE, followed by B+M, gave the highest values of the free proline content in the two cuts for the two seasons compared to the control. It was proven that total phenol content was affected by the different growth stimulant treatments. Foliar application of the growth stimulants increased the total phenol content compared to the control. However, application of MLE resulted in the highest values of total phenol content in the two cuts for the two seasons compared to the control. Among the growth stimulants used, foliar spraying with MLE, followed by microorganisms (B+M), shows a superior effect in decreasing the accumulation of sodium and chlorine compared to other stimulants, while improving potassium was obtained by the growth stimulants MLE, B+A, and BAP, respectively, in both seasons.
Influence of Nanofluids on Boundary Layer Flow over an Inclined Stretching Sheet in a Porous Media along with Magnetic Field
Authors: Bansal Sham , Pal Jai , Bisht Mangal Singh , Fartyal Prachi
Published: February 2024

The current study intends to analyse the magnetohydrodynamics boundary layer flow of a water-based nanofluid of Silver, Copper and Ferrous Ferric Oxide nanoparticles over a Permeable inclined stretched sheet in a porous media. A similarity transformation is utilized to convert the governing partial differential equations into non-dimensional, non-linear ordinary differential equations. The Keller box finite difference implicit approach is then applied to solve these nonlinear equations numerically. The impacts of several parameters, namely, inclination parameter, magnetic parameter, Soret Number, Eckertnumber and nano particles volume fractionon velocity, temperature and nanoparticle concentration are explored.
Scientific Mapping of Chatbot Literature: A Bibliometric Analysis
Authors: Tanwar Manju , Verma Harsh V.
Published: February 2024

The use of chatbots for customer service has gained momentum in recent years. Increasing evidence has shown that chatbots can transform the customer service landscape. Nevertheless, this topic currently lacks adequate bibliometric and visualization research. In order to review and summarise the research on chatbots, the study employs a bibliometric analysis approach to gain a comprehensive understanding of chatbots. The study uses bibliometric analysis of 798 documents sourced from the Scopus database from 2001 to 2022. The combination of biblioshiny (web interface application of Bibliometrix) and VOS viewer software was used to visualize the analysis. The study's findings reveal three prominent areas in the current research: antecedents of the adoption of chatbots, application of chatbots and behavioural & relational outcomes of the application of chatbots. The future directions and implications have been discussed in the study's conclusion.
Space-time reconstruction of a moving acoustic loading on a membrane by coupling the force analysis technique and full-field non-contact vibration measurements
Authors: Mougey Anaïs , Robin Olivier , Melon Manuel
Published: February 2024

Identifying acoustical and mechanical loadings on structures is a common problem in acoustics and vibration analysis and stationary loadings are mostly considered on plate-like structures. This work describes a proof of concept for reconstructing the trajectory of an acoustic source moving in front of a membrane. Compared with works focusing on precisely identifying a loading’s amplitude at a given location, the objective is to reconstruct the loading’s trajectory–Qualitative loading identification is sought rather than quantitative. The force analysis technique is used to recover a space-time varying loading on a structure, starting from time-resolved full-field non-contact vibration measurements conducted on a circular membrane. At the same time, a compact and tonal sound source is used to draw freehand shapes in front of the membrane. The loading trajectory, therefore, contains information that was “acoustically written”. Simple hand gestures that correspond to the drawing of a Greek letter (Σ), a capital letter (P), two shapes (♡, ⋆), and a 3-letter word (net) are recovered using the proposed procedure. The effect of various parameters on the reconstructed information is studied. Perspectives in terms of possible research areas and applications are finally discussed. These perspectives include, for example, the use of membranes to help reconstruct complex and space-time-varying loadings or even applications in musical acoustics on membranophones.
Dynamic cerebral blood flow assessment based on electromagnetic coupling sensing and image feature analysis
Authors: Gong Zhiwei , Zeng Lingxi , Jiang Bin , Zhu Rui , Wang Junjie , Li Mingyan , Shao Ansheng , Lv Zexiang , Zhang Maoting , Guo Lei , Li Gen , Sun Jian , Chen Yujie
Published: February 2024

Dynamic assessment of cerebral blood flow (CBF) is crucial for guiding personalized management and treatment strategies, and improving the prognosis of stroke. However, a safe, reliable, and effective method for dynamic CBF evaluation is currently lacking in clinical practice. In this study, we developed a CBF monitoring system utilizing electromagnetic coupling sensing (ECS). This system detects variations in brain conductivity and dielectric constant by identifying the resonant frequency (RF) in an equivalent circuit containing both magnetic induction and electrical coupling. We evaluated the performance of the system using a self-made physical model of blood vessel pulsation to test pulsatile CBF. Additionally, we recruited 29 healthy volunteers to monitor cerebral oxygen (CO), cerebral blood flow velocity (CBFV) data and RF data before and after caffeine consumption. We analyzed RF and CBFV trends during immediate responses to abnormal intracranial blood supply, induced by changes in vascular stiffness, and compared them with CO data. Furthermore, we explored a method of dynamically assessing the overall level of CBF by leveraging image feature analysis. Experimental testing substantiates that this system provides a detection range and depth enhanced by three to four times compared to conventional electromagnetic detection techniques, thereby comprehensively covering the principal intracranial blood supply areas. And the system effectively captures CBF responses under different intravascular pressure stimulations. In healthy volunteers, as cerebral vascular stiffness increases and CO decreases due to caffeine intake, the RF pulsation amplitude diminishes progressively. Upon extraction and selection of image features, widely used machine learning algorithms exhibit commendable performance in classifying overall CBF levels. These results highlight that our proposed methodology, predicated on ECS and image feature analysis, enables the capture of immediate responses of abnormal intracranial blood supply triggered by alterations in vascular stiffness. Moreover, it provides an accurate diagnosis of the overall CBF level under varying physiological conditions.
Magnetic propelled hydrogel microrobots for actively enhancing the efficiency of lycorine hydrochloride to suppress colorectal cancer
Authors: Jiang Fengqi , Zheng Qiuyan , Zhao Qingsong , Qi Zijuan , Wu Di , Li Wenzhong , Wu Xiaoke , Han Conghui
Published: February 2024

Research and development in the field of micro/nano-robots have made significant progress in the past, especially in the field of clinical medicine, where further research may lead to many revolutionary achievements. Through the research and experiment of microrobots, a controllable drug delivery system will be realized, which will solve many problems in drug treatment. In this work, we design and study the ability of magnetic-driven hydrogel microrobots to carry Lycorine hydrochloride (LH) to inhibit colorectal cancer (CRC) cells. We have successfully designed a magnetic field driven, biocompatible drug carrying hydrogel microsphere robot with Fe3O4 particles inside, which can achieve magnetic field response, and confirmed that it can transport drug through fluorescence microscope. We have successfully demonstrated the motion mode of hydrogel microrobots driven by a rotating external magnetic field. This driving method allows the microrobots to move in a precise and controllable manner, providing tremendous potential for their use in various applications. Finally, we selected drug LH and loaded it into the hydrogel microrobot for a series of experiments. LH significantly inhibited CRC cells proliferation in a dose- and time-dependent manner. LH inhibited the proliferation, mobility of CRC cells and induced apoptosis. This delivery system can significantly improve the therapeutic effect of drugs on tumors.
A bipartite NLS motif mediates the nuclear import of Drosophila moesin
Authors: Kovács Zoltán , Bajusz Csaba , Szabó Anikó , Borkúti Péter , Vedelek Balázs , Benke Réka , Lipinszki Zoltán , Kristó Ildikó , Vilmos Péter
Published: February 2024

The ERM protein family, which consists of three closely related proteins in vertebrates, ezrin, radixin, and moesin (ERM), is an ancient and important group of cytoplasmic actin-binding and organizing proteins. With their FERM domain, ERMs bind various transmembrane proteins and anchor them to the actin cortex through their C-terminal F-actin binding domain, thus they are major regulators of actin dynamics in the cell. ERMs participate in many fundamental cellular processes, such as phagocytosis, microvilli formation, T-cell activation and tumor metastasis. We have previously shown that, besides its cytoplasmic activities, the single ERM protein of Drosophila melanogaster, moesin, is also present in the cell nucleus, where it participates in gene expression and mRNA export. Here we study the mechanism by which moesin enters the nucleus. We show that the nuclear import of moesin is an NLS-mediated, active process. The nuclear localization sequence of the moesin protein is an evolutionarily highly conserved, conventional bipartite motif located on the surface of the FERM domain. Our experiments also reveal that the nuclear import of moesin does not require PIP2 binding or protein activation, and occurs in monomeric form. We propose, that the balance between the phosphorylated and non-phosphorylated protein pools determines the degree of nuclear import of moesin.
Natural products as a source of Coronavirus entry inhibitors
Authors: Szabó Dávid , Crowe Andrew , Mamotte Cyril , Strappe Padraig
Published: February 2024

The COVID-19 pandemic has had a significant and lasting impact on the world. Four years on, despite the existence of effective vaccines, the continuous emergence of new SARS-CoV-2 variants remains a challenge for long-term immunity. Additionally, there remain few purpose-built antivirals to protect individuals at risk of severe disease in the event of future coronavirus outbreaks. A promising mechanism of action for novel coronavirus antivirals is the inhibition of viral entry. To facilitate entry, the coronavirus spike glycoprotein interacts with angiotensin converting enzyme 2 (ACE2) on respiratory epithelial cells. Blocking this interaction and consequently viral replication may be an effective strategy for treating infection, however further research is needed to better characterize candidate molecules with antiviral activity before progressing to animal studies and clinical trials. In general, antiviral drugs are developed from purely synthetic compounds or synthetic derivatives of natural products such as plant secondary metabolites. While the former is often favored due to the higher specificity afforded by rational drug design, natural products offer several unique advantages that make them worthy of further study including diverse bioactivity and the ability to work synergistically with other drugs. Accordingly, there has recently been a renewed interest in natural product-derived antivirals in the wake of the COVID-19 pandemic. This review provides a summary of recent research into coronavirus entry inhibitors, with a focus on natural compounds derived from plants, honey, and marine sponges.
Prospects of cognitive-motor entrainment: an interdisciplinary review
Authors: Schmid Daphne G.
Published: February 2024

Entrainment theory, a multidisciplinary concept referring to the automatic synchronization of oscillatory patterns, can be used to explain interactions across motor production, cognition, and environmental processing. This review summarizes findings from the three primary categories of naturally occurring neural entrainment: body-brain entrainment of involuntary self-produced rhythms, bottom-up entrainment between environmental stimuli and the brain, and top-down neural entrainment of self-produced processes. Studies evaluating entrainment's impact on cognition suggest that synchronized neural activation may alleviate cognitive constraints. Entrainment has also been therapeutically implemented to decrease motor production variation and enhance movement quality. When considering the evidence for entrainment's ability to decrease the attentional load of a task and increase cognitive or motor production quality, the oscillatory synchronization of a cognitive and motor task may be a promising technique that can be applied to dual-tasking. An emerging body of literature suggests that cognitive-motor entrainment may alleviate dual-task cost and, in some cases, lead to a higher quality of psychological and physiological task performance than when the same tasks are performed in isolation. We propose pathways for future research and emphasize the therapeutic relevance further experimentation on the topic of entrainment may provide. By understanding how to maximize neural entrainment's cognitive and motor benefits, scientists and practitioners may be able to harness its benefits to enhance learning and rehabilitative practices.
Early and late outcomes after minimally invasive direct coronary artery bypass vs. full sternotomy off-pump coronary artery bypass grafting
Authors: Sharaf Mohammad , Zittermann Armin , Sunavsky Jakub , Gilis-Januszewski Tomasz , Rojas Sebastian V. , Götte Julia , Opacic Dragan , Radakovic Darko , El-Hachem Georges , Razumov Artyom , Renner Andre , Gummert Jan F. , Deutsch Marcus-André
Published: February 2024

Objectives

Minimally-invasive direct coronary artery bypass (MIDCAB) is a less-invasive alternative to full sternotomy off-pump coronary artery bypass (FS-OPCAB) revascularization of the left anterior descending artery (LAD). Some studies suggested that MIDCAB is associated with a greater risk of graft occlusion and repeat revascularization than FS-OPCAB LIMA-to-LAD grafting. Data comparing MIDCAB to FS-OPCAB with regard to long-term follow-up is scarce. We compared short- and long-term results of MIDCAB vs. FS-OPCAB revascularization over a maximum follow-up period of 10 years.

Patients and methods

From December 2009 to June 2020, 388 elective patients were included in our retrospective study. 229 underwent MIDCAB, and 159 underwent FS-OPCAB LIMA-to-LAD grafting. Inverse probability of treatment weighting (IPTW) was used to adjust for selection bias and to estimate treatment effects on short- and long-term outcomes. IPTW-adjusted Kaplan–Meier estimates by study group were calculated for all-cause mortality, stroke, the risk of repeat revascularization and myocardial infarction up to a maximum follow-up of 10 years.

Results

MIDCAB patients had less rethoracotomies (n = 13/3.6% vs. n = 30/8.0%, p = 0.012), fewer transfusions (0.93 units ± 1.83 vs. 1.61 units ± 2.52, p < 0.001), shorter mechanical ventilation time (7.6 ± 4.7 h vs. 12.1 ± 26.4 h, p = 0.005), and needed less hemofiltration (n = 0/0% vs. n = 8/2.4%, p = 0.004). Thirty-day mortality did not differ significantly between the two groups (n = 0/0% vs. n = 3/0.8%, p = 0.25). Long-term outcomes did not differ significantly between study groups. In the FS-OPCAB group, the probability of survival at 1, 5, and 10 years was 98.4%, 87.8%, and 71.7%, respectively. In the MIDCAB group, the corresponding values were 98.4%, 87.7%, and 68.7%, respectively (RR1.24, CI0.87–1.86, p = 0.7). In the FS group, the freedom from stroke at 1, 5, and 10 years was 97.0%, 93.0%, and 93.0%, respectively. In the MIDCAB group, the corresponding values were 98.5%, 96.9%, and 94.3%, respectively (RR0.52, CI0.25–1.09, p = 0.06). Freedom from repeat revascularization at 1, 5, and 10 years in the FS-OPCAB group was 92.2%, 84.7%, and 79.5%, respectively. In the MIDCAB group, the corresponding values were 94.8%, 90.2%, and 81.7%, respectively (RR0.73, CI0.47–1.16, p = 0.22).

Conclusion

MIDCAB is a safe and efficacious technique and offers comparable long-term results regarding mortality, stroke, repeat revascularization, and freedom from myocardial infarction when compared to FS-OPCAB.