bluuebunny/crossref_metadata_2025 huggingface dataset:
Nose-to-brain Drug Delivery System: An Emerging Approach to Chemotherapy-induced Cognitive Impairment
Authors: Jannapu Reddy Shireesha , Mutalik Srinivas , Viswanatha Gollapalle Lakshminarayanashastry , Kumar Gautam , John Jeena , Chamallamudi Mallikarjuna Rao , Das Arpita , Das Sudip , Nandakumar Krishnadas
Published: May 2024

The rise in global cancer burden, notably breast cancer, emphasizes the need to address
chemotherapy-induced cognitive impairment, also known as chemobrain. Although chemotherapy
drugs are effective against cancer, they can trigger cognitive deficits. This has triggered the exploration
of preventive strategies and novel therapeutic approaches. Nanomedicine is evolving as a
promising tool to be used for the mitigation of chemobrain by overcoming the blood-brain barrier
(BBB) with innovative drug delivery systems. Polymer and lipid-based nanoparticles enable targeted
drug release, enhancing therapeutic effectiveness. Utilizing the intranasal route of administration
may facilitate drug delivery to the central nervous system (CNS) by circumventing first-pass metabolism.
Therefore, knowledge of nasal anatomy is critical for optimizing drug delivery via various
pathways. Despite challenges, nanoformulations exhibit the potential in enhancing brain drug delivery.
Continuous research into formulation techniques and chemobrain mechanisms is vital for developing
effective treatments. The intranasal administration of nanoformulations holds promise for
improving therapeutic outcomes in chemobrain management. This review offers insights into potential
future research directions, such as exploring novel drug combinations, investigating alternative
delivery routes, or integrating emerging technologies to enhance the efficacy and safety of
nanoformulations for chemobrain management.
Nano-Formulation Approaches to Enhance Transdermal Drug Delivery-An Updated Review of Nanovesicular Carrier “Transethosomes”
Authors: Singh Jitendra Pratap , Saini Geetanjali , Tiwari Gaurav , Singh Bhupendra
Published: May 2024

Transdermal drug delivery is an attractive and patient-friendly route for administering
therapeutic agents. However, the skin's natural barrier, the stratum corneum, restricts the passage of
many drugs, limiting their effectiveness. To overcome this challenge, researchers have developed
various nanocarriers to enhance drug penetration through the skin. Transethosomes, a novel and
promising drug delivery system, have emerged as an innovative solution for improving transdermal
drug delivery. Transethosomes are a hybrid of two established nanocarriers: ethosomes and transfersomes.
Ethosomes are lipid-based vesicles that can accommodate lipophilic and hydrophilic
drugs, while transfersomes are deformable lipid vesicles designed to enhance skin penetration.
Transethosomes combine the advantages of both systems, making them ideal candidates for efficient
transdermal drug delivery. They are composed of phospholipids, ethanol, and water and exhibit
high flexibility, enabling them to squeeze through the tight junctions of the stratum corneum. This
abstract reviews the key characteristics of transethosomes, including their composition, preparation
methods, mechanisms of action, characterization parameters, and prospects. Moreover, the recent
advancements and applications of transethosomes in delivering various therapeutic agents, such as
analgesics, anti-inflammatories, hormones, and skincare products, are explored. The enhanced skin
penetration capabilities of transethosomes can potentially reduce systemic side effects and improve
patient compliance, making them a valuable tool in the field of transdermal drug delivery. In conclusion,
transethosomes represent a promising platform for overcoming the challenges of transdermal
drug delivery. Their unique properties enable efficient drug permeation through the skin, offering
a more controlled and effective means of administering a wide range of pharmaceutical and
cosmetic products. This abstract highlights the potential of transethosomes as a valuable addition to
the field of transdermal drug delivery and paves the way for further research and development in
this area.
Antimicrobial Therapy in Dentistry: An Evidence-based Review of
Pomegranate Fruit Properties
Authors: Martins Almeida Nara Lígia , Ferreira Peralta Laura Catalí , Soares Lara Vanessa
Published: May 2024

Background:

Phytotherapy is characterized by the use of medicinal plants in their different
dosage forms. Currently, the use of this alternative medicine has increased. The raw material
of herbal medicines consists of organs from medicinal plants (leaves, stems, fruits, peels,
flowers and roots) with pharmacological, food, technical or cosmetic adjuvant effects. In addition,
the side effects of its use appear to be reduced compared to synthetic and conventional medication.

Objective:

The aim of this mini-review is to present the scientific evidence involving the properties
of the pomegranate fruit for future antimicrobial applications in dentistry.

Methods:

Literature searches included randomized clinical trials and in vitro studies [2000-2023]
filtered mainly by the following terms [Punica granatum L.], [Pomegranate], [Dentistry], [Antimicrobial
activity] and [Candida albicans].

Results:

Studies have shown that Punica granatum Linn. has considerable antimicrobial activity,
in addition to other pharmacological effects such as anti-cancer, antioxidant and antiinflammatory
action. The use of herbal medicines, as potent antimicrobial agents against oral
pathogens, has been widely reported.

Conclusion:

The use of P. granatum has proven its effectiveness, as a potent antimicrobial agent
against oral pathogens, especially against the fungus Candida albicans, future studies need to focus
on the development of a biocompatible formulation directed to the treatment of patients with
oral candidiasis.
sociolinguistic analysis of code switching in medical register
Authors: Ayuuf Husein Hameed M , Majeed Serin
Published: May 2024

The research work is associated with identifying an in-depth understanding about the ways that are used by patients and practitioners to handle the medical registers of language in medical communication. The research works focuses on the code-switching approaches in the medical communication that is important in patients. However, some challenges are associated with code switching usage in medical communication due to the usage of code switching along with its frequency as well as pattern of code switching. Previous researchers have focused on the impact of patient education level in code switching as well as the role of doctors to handle the approaches. The study is also supported by the concepts of theory of language acquisition device. However, previous research has not focused on the role of administration and leadership in that particular field. A descriptive research design is followed in order to collect primary data from the medical practitioners in order to generate further outcomes that can be valued in that particular research field. Software like IBM SPSS is used to generate results from the collected quantitative data.
Quality of life and strength, but not cytokines, are associated with DAS-28 in active and inactive rheumatoid arthritis
Authors: Travizan Marina Silva , Vitaliano Graminha Cristiane , Ratkevicius Cristhiane Molinero Andrade , Assunção Thaís Soares Farnesi , Botelho Teodoro Reginaldo , Stefenoni Krüger Gabriella , Jerônimo Erik Augusto , Pessato Timóteo Rodolfo
Published: May 2024

Objective: Evaluate and correlate data between relevant cytokines, disease progression, and handgrip and quality of life among RA patients at different stages of disease progression. Method: Thirty-three RA patients were recruited for analysis, using comparisons and correlations, between levels of circulating cytokines (IFN-γ, TNF-α, IL-4, IL-6, IL-10, IL-17, IL-1β, and TNF receptors I and II), activity of the disease (evaluated using the DAS-28), handgrip (Hydraulic dynamometer), and quality of life (SF-36). Result: RA patients in different disease stages showed increases of IL-6 and IL-10 compared control group. Positive correlation between IL-6 with TNF-α, and IL-4 with IL-10 was found. Handgrip strength and quality of life were not related to cytokine levels. However, remission patients had better strength and quality of life indices compared to the active patients. In addition, handgrip of the non-dominant side, physical functions, role limitations physical health, pain, energy/fatigue and social functions have a negative correlation with the DAS28-PCR. Conclusion: High levels of IL-6 and IL-10 were observed in the chronic RA patients, but the values did not show correlation with disease activity, handgrip strength and quality of life. Disease activity show correlation with handgrip strength and quality of life. Furthermore, remission patients had better strength and quality of life indices compared to the active patients.
Opportunities and Challenges Surrounding the Use of Wearable Sensor Bracelets for Infectious Disease Detection During Hajj: A Qualitative Interview Study (Preprint)
Authors: Maddah Noha , Verma Arpana , Ainsworth John
Published: May 2024

BACKGROUND

Wearable sensor bracelets have gained interest for their ability to detect symptomatic and presymptomatic infections by detecting alterations in physiological indicators. Nevertheless, the utilisation of these devices for public health surveillance among attendees of large-scale events like Hajj is currently in a nascent phase.

OBJECTIVE

To explore Hajj stakeholders’ perspectives on the use of wearable sensor bracelets for disease detection.

METHODS

We conducted a qualitative, theoretically informed, interview-based study involving a diverse sample of Hajj stakeholders, including technology experts, healthcare providers, and Hajj service providers. The study was guided by the Task-Technology Fit Model (TTF) and Unified Theory of Acceptance and Use of Technology (UTAUT) to provide a comprehensive understanding of the factors influencing the acceptance and utilisation of the technology. Semi-structured in-depth interviews were employed to capture perspectives on using wearable sensor bracelets for infectious disease detection in Hajj. Thematic analysis of interview transcripts was conducted.

RESULTS

A total of 14 individuals were interviewed.Implementing wearable sensor bracelets for disease detection during Hajj faces obstacles from multiple perspectives, encompassing users, providers, and technological factors. Hajj stakeholders are concerned about the substantial financial and operational barriers. The motivation of providers and users is essential for the acceptance and uptake of devices during Hajj. Successful integration of wearables into the Hajj surveillance system depends on several factors, including infrastructure, device features, suitable use cases, training, and a smooth organisational integration process.

CONCLUSIONS

This study provides valuable insights into the potential opportunities and challenges of adopting wearable sensor bracelets for disease detection during Hajj. It offers essential factors to consider and important suggestions to enhance comprehension and ensure the effective implementation of this technology.
EXPANDED DENGUE SYNDROME AND ATYPICAL MANIFESTATIONS
Authors: HASEEB ABDUL , HAREESH  , SHARANABASAPPA
Published: May 2024

Objective: Dengue fever, once seen as a classical febrile illness, has transformed into a global concern with the emergence of Expanded Dengue Syndrome (EDS). EDS is characterized by atypical and severe manifestations affecting multiple organ systems, including the central nervous system, liver, heart, and kidneys. This syndrome challenges the traditional understanding of dengue and necessitates heightened clinical awareness, timely intervention, and comprehensive research. Co-infections further complicate the clinical landscape, emphasizing the need for accurate diagnosis and targeted therapeutic strategies.
Methods: This prospective observational study was conducted at Yashoda Super Specialty Hospital, Malakpet, Hyderabad, from January 2018 to January 2021. The study aimed to identify and analyze atypical presentations of dengue fever in patients of all age groups. Inclusion criteria involved laboratory-confirmed dengue cases with atypical manifestations indicative of EDS. Data collection included comprehensive clinical, laboratory, and radiological information. Ethical considerations and statistical analysis were conducted using SPSS software.
Results: The study analyzed 150 cases of EDS, encompassing atypical manifestations such as encephalopathy, myocarditis, acute liver failure, and renal impairment. CNS involvement was the most common atypical manifestation (20%), followed by myocarditis (15%) and acute liver failure (10%). Renal impairment was observed in 5% of cases. Co-infections were identified in 25% of EDS cases, further complicating clinical management. The mortality rate among EDS patients was 5%, emphasizing the importance of early recognition and aggressive organ-specific interventions.
Conclusion: Expanded Dengue Syndrome challenges the conventional perception of dengue fever, highlighting atypical manifestations and co-infections. Heightened clinical awareness, a broad differential diagnosis, and aggressive management strategies are essential for addressing the multifaceted nature of EDS. Further research is needed to develop targeted interventions for this complex and evolving disease.
THORACIC SEGMENTAL SPINAL ANAESTHESIA IN UPPER ABDOMINAL SURGERIES AND SIMPLE MASTECTOMY-A CASE SERIES
Authors: BORAH MADHUCHANDA , DAS KAVERI , AHIR BIJOY , VERMA ANJALI , GOWTHAM PYDIMALLA VENKATA , DAS KARUNA KUMAR , BARUAH PRITANU DEB
Published: May 2024

Objective: To observe safety and efficacy of Segmental thoracic spinal anesthesia (STSA) in upper abdominal and breast surgeries.
Methods: 14 cases were selected, out of which 6 laparoscopic cholecystectomy (LC), 4 open cholecystectomy (OC), 3 emergency exploratory laparotomy and 1 simple mastectomy. Under full aseptic precaution, segmental thoracic spinal anesthesia was administered through midline approach in T8-9 space for upper abdominal surgeries and T5-6 space in a simple mastectomy. Using 25G Quincke spinal needle 1.5 ml [7.5 mg] of 0.5% Isobaric Levobupivacaine mixed with 0.4 ml (20µg) Fentanyl was given in abdominal surgeries and 1.2 ml [6 mg] of 0.5% Isobaric Levobupivacaine mixed with 0.4 ml (20µg) Fentanyl in simple mastectomy.
Results: Age group of patients ranged from 25 to 65 y, Male: Female ratio of 4:10, Body Mass Index (BMI) range of 22 to 24.9 with physiological status of ASA I to ASA III. Hemodynamically, hypotension was observed in every patient after 5-10 min of STSA well managed with fluid and vasopressors with no bradycardia. Average width of sensory block was T3 to L1-2 in upper abdominal surgeries and T1 to T8 in a simple mastectomy. Motor block was Modified Bromage Scale (MBS) of 0 to 1 during and postoperatively. Regarding analgesia, Visual Analogue Scale (VAS) score was 0 intraoperatively and 0-1 postoperatively. Sedation score was 2 both intraoperatively and postoperatively with no significant complications and good patient and surgeon satisfaction.
Conclusion: Segmental thoracic spinal anaesthesia is a safe and effective procedure with good patient and surgeon satisfaction.
The Function of the Thing in the Motif of the Path (based on the material of the Kalmyk fairy tale)
Authors: Goryaeva Baira
Published: May 2024

Introduction. When studying a thing, the main defining principle of it is the main property or function that it performs. Function is the basis for the systematics of things in research. Results. The analysis of the texts of Kalmyk fairy tales showed that when setting out on a journey, the characters take with them things that once accompanied a person at a funeral, the transition to another world. The length of the path in the fairy tale is conveyed through the description of iron, implying strength, objects that wear out by the end of the path. On the Kalmyk material, there is a case of adding a staff and shoes with other things made of iron (a three-layer shell from a boiler, a three-layer helmet from a flat-bottomed boiler). The material of the Kalmyk fairy tale provides an expansion of the number of iron objects, which, under the influence of fairy-tale tradition, along with a staff and shoes, also appear to be iron. When setting off on a long journey to another world, the wonderful spouse gives him a ball of threads, which performs a guiding function in the fairy tale and things-attributes (a golden comb, a yellow-mottled handkerchief and a golden ring) that have the function of identification. In the motif of the way, the Kalmyk fairy tale complements the magic carpet with two more objects and gives the trinity of these things one function — transport. When escaping from man-eating mousses, things are used that transform the fabulous space received from parents. The grindstone, the chopping block and the skimmer turn into insurmountable mountains and a dense forest. From his father, the hero, who sets off on a journey, also receives a sword, which is stealthily used by a magical assistant for its intended purpose and imperceptibly returned to the hero. The texts on the “Grateful Dead” plot type show that the hero, the begged son of wealthy parents or the khan’s son, sets off on a journey with gold and silver, money that has a stable associative connection with the “other” world. When considering the function of an item in the motif of the Kalmyk fairy tale path, universal objects (staff, shoes, food, money) used in traditional rites of passage by many peoples, including the Kalmyks, as well as a specific one borrowed from the culture of the Russian people — the clay pot buhsh, which is unconventional for the life of the Kalmyk people, are noted.
The Poetics of Things in the Book of Skaz (Folk Tales) «The Malachite Casket» by P. P. Bazhov
Authors: Ivanova Irina , Lepilkina Olga
Published: May 2024

The article deals with P. P. Bazhov’s world of things as an aesthetic unity. The book of skaz (folk tales) of the Ural writer is a unique artistic world, the structure of which is defined by a system of several basic oppositions. It is a world extremely full of things, such as household items (people’s everyday lives), clothes (social status, the «us-them» divide), instruments and tools of craft (key topics of handicraft / craftsmanship) etc. A special role in this objective world is played by artisan products that combine the functions of a household item, an artefact and a magical object, and magical objects per se that are received from a donor but are usually different in function from their proper fairytale counterparts, which are common to the traditional Russian folklore and literary fairytales based on folklore stories. Bazhov’s system of images-things also includes a specific «human as a thing» category that is connected with the main conflicts of the book depicting serfdom-based mining civilization. Generally, the peculiarity of the world of things in «The Malachite Casket» is defined by the «borderline» nature of the skaz genre, its complex relationship with folklore and the unique character of Bazhov’s aesthetic experiment.
La oportunidad para impulsar un nuevo avance en la jurisdicción administrativa federal
Authors: Carballo Balvanera Luis
Published: May 2024

Número 100Enero - Abril 2001Nueva Serie Año XXXIVISSN 0041 8633 AVANCE EN LA JURISDICCIÓN ADMINISTRATIVA FEDERAL Luis CARBALLO BALVANERA * El cambio profundo que ha ocurrido en el derecho administrativo mexicano, exige una revisión de las normas relativas a la justicia administrativa. Siguiendo esta propuesta, el autor realiza primero una reseña de los cambios a la legislación administrativa sustantiva, para después estudiar algunos aspectos relativos al procedimiento contencioso-administrativo. Entre las leyes estudiadas están las relativas a las materias fiscal, de seguridad social, ecología, y procedimiento administrativo, todas a nivel federal. Asimismo, se hacen algunas propuestas, como la de ampliar la cobertura de la suspensión del acto impugnado, la modernización de las formas de notificación dentro de los procedimientos seguidos ante el Tribunal Fiscal de la Federación, la ampliación de las facultades de este mismo tribunal para que de comprobar la ilegalidad del acto impugnado lo anule y determine el alcance de su sentencia, y dotar a dicho tribunal de plena autonomía presupuestal y organizacional, entre muchas otras., *Magistrado del Tribunal Fiscal de la Federación, Sala Superior, Segunda Sección. * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.
Pluralidad de formas de celebración y matrimonio musulmán. Una perspectiva desde el derecho internacional privado español
Authors: Blázquez Rodríguez Irene
Published: May 2024

Número 110Mayo - Agosto 2004Nueva Serie Año XXXVIIISSN 0041 8633 PLURALIDAD DE FORMAS DE CELEBRACIÓN Y MATRIMONIO MUSULMÁN. UNA PERSPECTIVA DESDE EL DERECHO INTERNACIONAL PRIVADO ESPAÑOL Irene BLÁZQUEZ RODRÍGUEZ * Pese a las diferencias en cuanto a la concepción del matrimonio en Occidente y en el mundo musulmán, ambas realidades coinciden en que se trata de una institución clave que, como tal, es objeto de especial protección jurídica. Sin embargo, más allá de esta coincidencia, las diferencias son notables en cuanto a las reglas que gobiernan la institución en ambas tradiciones jurídicas. Ello genera problemas especialmente en países que, como la España actual, son receptores de grandes contingentes de población musulmana. En el encuentro humano, cultural y jurídico que la inmigración propicia, el derecho internacional privado juega un papel relevante por ser el sector del ordenamiento jurídico llamado a solucionar multitud de controversias que afloran de tal multiculturalidad. De esta manera, el objetivo en este trabajo es, cumplidos diez años de la vigencia de la Ley 26/1992, realizar una reflexión sobre la celebración del matrimonio musulmán en España. Palabras clave: matrimonio, tradición jurídica, derecho musulmán, conflicto de leyes. *Profesora de derecho internacional privado y doctora en derecho en la Universidad de Córdoba. * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.
Deep Learning Approach for Early Detection of Alzheimers Disease
Authors: Dandwate Nishant
Published: May 2024

Abstract: Alzheimer’s disease (AD) is a chronic, irreversible brain disorder, no effective cure for it till now. However, available medicines can delay its progress. Therefore, the early detection of AD plays a crucial role in preventing and controlling its progression. The main objective is to design an end-to-end framework for early detection of Alzheimer’s disease and medical image classification for various AD stages. A deep learning approach, specifically convolutional neural networks (CNN), is used in this work. Four stages of the AD spectrum are multi-classified. Furthermore, separate binary medical image classifications are implemented between each two-pair class of AD stages.
Implementation of Autonomous Drone for Flood Surveillance
Authors: Chandraiah G. , Latha M. Swarna , Hema K. , Kaavya H. , Reddy K. Vijay Simha , Babu J. Dilip
Published: May 2024

Abstract: Floods are natural disasters that pose significant challenges to both the safety of communities and the effectiveness of response efforts. In recent years, the integration of unmanned aerial vehicles, commonly known as drones, has emerged as a valuable tool in flood surveillance. This paper provides an overview of the multifaceted role of drones in flood-related scenarios, highlighting their capabilities, benefits, and potential challenges. Drones have demonstrated their versatility in flood management by offering several critical functions. Drones enhance the safety of response teams by providing situational awareness without exposing personnel to hazardous conditions. They can be deployed to access remote or inaccessible areas, where human intervention is challenging or dangerous. Drones equipped with thermal imaging cameras also support search and rescue missions, increasing the chances of locating and saving individuals trapped by floodwaters. In addition to assessment and rescue, drones contribute to flood forecasting and early warning systems. By continuously monitoring water levels, weather conditions, and flood dynamics, drones provide essential data for improving flood prediction models. This information helps authorities issue timely warnings, enabling communities to prepare and evacuate when necessary.
PENGARUH LITERASI KEUANGAN DAN PERILAKU KEUANGAN TERHADAP KEPUTUSAN INVESTASI DI CRYPTO
Authors: Muhammad Distian Andi Hermawan
Published: May 2024

The problem that occurs is that the people of Palembang do not understand where to start investing.  This is based on the ability of a low level of financial literacy. This study aims to see the influence of financial literacy and financial behavior either partially or simultaneously. This study uses a quantitative approach where the data obtained uses questionnaires or questionnaires in the form of questions asked to respondents. Respondents is used in this study are 30 respondents. Analysis technique used linear regression. The results of this study show that Variable (X1) Financial Literacy does not have a partial influence on Variable (Y) Investment Decisions. Variable X2 Financial Behavior has a positive and significant influence on Variable (Y) Investment Decisions. The simultaneous test show that both Independent Variables (X1) Financial literacy and (X2) Financial behavior have a positive and significant influence on the Dependent Variable (Y) Investment Decision.
Ethical leadership and organizational performance: Employee happiness as a mediator and corporate social responsibility as a moderator
Authors: Fendui Qin , Naveed Rana Tahir , Adnan Mohammad , Kanwal Sara
Published: May 2024

In the resource-constrained context of Pakistan's healthcare sector, the role of employee happiness in influencing organizational performance remains underexplored. Our study addressed this gap by examining how ethical leadership and corporate social responsibility (CSR) influence organizational
outcomes via employee happiness. Utilizing a cross-sectional design with data from healthcare professionals and applying structural equation modeling, we found that ethical leadership significantly boosted employee happiness, which, in turn, enhanced organizational performance. Further, CSR
strengthened the relationship between ethical leadership and happiness. The findings not only emphasize the centrality of employee happiness in mediating leadership and performance linkages but also offer insights for improving healthcare services in similar contexts.
Physical exercise and positive coping styles of Chinese college students: Psychological resilience as a mediator
Authors: Zhang Jinrui , Liu Han , Dai Weinan
Published: May 2024

We investigated the impact of the intensity, frequency, and duration of engaging in physical exercise on positive coping styles among 376 college students in China, and assessed the mediating role of psychological resilience in this relationship. The results revealed there was a significant
positive correlation between engaging in physical exercise and positive coping styles. Additionally, psychological resilience mediated the relationship between physical exercise and positive coping styles. Our findings contribute to understanding of the interplay among physical exercise, positive
coping styles, and psychological resilience among college students within the context of Chinese higher education. The findings also offer practical insights for educators to enhance positive coping styles among college students. Directions for future research are suggested.
Teacher–student relationships and student engagement: The mediating effect of peer relationships
Authors: Wang Zhongqiang , Yuan Li
Published: May 2024

Previous research has shown that teacher–student relationships influence student engagement, which, in turn, plays a key role in academic achievement. However, few studies have focused on the mechanism between the teacher–student relationship and student engagement. To address
this gap in the literature, this study examined the link between teacher–student relationships and college students' engagement via the mediator of peer relationships. The sample consisted of 222 university students in Southwest China. Results of structural equation modeling showed that
a positive teacher–student relationship was positively related to student engagement, and peer relationships partially mediated this relationship. Our findings will help researchers and educators to better understand the mechanism of the link between teacher–student relationships
and student engagement, and provide practical suggestions for improving college students' engagement.
Mechanisms of the impact of sports participation on college students' psychological well-being
Authors: Li Zhengkun , Huang Fang
Published: May 2024

We investigated the impact of sports participation on the psychological wellbeing of 563 college students in China, and assessed the mediating role of social development in this relationship. The results indicated there was a significant positive correlation between sports participation
and psychological well-being. Moreover, social development played a mediating role in the relationship between sports participation and psychological well-being. Our research findings contribute to understanding of the relationships among college students' sports participation, psychological
well-being, and social development within the context of higher education in China. These discoveries provide educators with practical insights to enhance college students' psychological well-being and suggest directions for future research.
Florescendo gênero
Authors: Amaral Walter Valdevino do
Published: May 2024

Este livro é fruto das discussões realizadas no I Encontro Florescendo Gênero. Cada capítulo apresenta uma narrativa que nos possibilita refletir sobre as relações de poder, culturais, religiosas e sociais a partir de suas conexões com os estudos de gênero, as quais estão perpassadas por diferentes temporalidades e espacialidades. A diversidade de olhares presente na escrita de cada texto, revela a multiplicidade de reflexões possíveis para compreensão das subjetividades que permeiam a construção das identidades, bem como denunciam os sistemas de desigualdades e exclusão com base na variedade das perspectivas de gênero e sexualidades. O processo de repensar e desconstruir visões engendradas historicamente, que contribuem para a disseminação de discursos e práticas do ódio, é uma tarefa, cada vez mais, necessária e desafiadora nos dias atuais. Florescendo gênero, despertaremos esperanças.
Time to Viral Clearance of SARS CoV-2 in Jamaica
Authors: Karen Webster-Kerr , Andriene Grant , Ardene Harris , Jovan Wiggan , Deborah Henningham , Daidre Rowe , Jemma Azille-Lewis , Romae Thorpe , Tanielle Mullings , Carol Lord , Tonia Dawkins-Beharie , Nicole Martin-Chen , Eon Campbell , Marsha Brown , Jacqueline Duncan
Published: May 2024

Background: PCR testing of respiratory tract specimens detects
SARS-CoV-2 viral shedding. Previous studies show that viral RNA was
detected from 1-83 days after COVID-19 symptom onset. This study aimed
to estimate time to viral clearance (TVC) for COVID-19 cases from
March-June 2020 in Jamaica. Methods: Cross-sectional analysis
was conducted on national surveillance data. Viral clearance was defined
as time from first positive nasopharyngeal swab to the first of two
consecutive negative tests. Confirmed cases and clinical severity were
based on WHO definitions. Frequency distributions, median and
interquartile ranges (IQR) were computed. Kruskal Wallis, Mann-Whitney U
and log rank tests evaluated differences by age, sex, and clinical
severity. Kaplan Meier curves described TVC by characteristics. A
p-value <0.05 was considered statistically significant.
Results: The analysis included 431 cases. Median TVC (days) was
28.0 (IQR: 18.0). Viral clearance differed by age (p<0.05),
sex (p<0.0001) and clinical severity (p<0.05). For
clinical severity, mildly ill cases had longest TVC (median: 29.0 days,
95%CI: 27-31). Females had a longer TVC (median: 30.0, 95%CI: 28-31)
than males (median: 23.0, 95%CI: 20-26). TVC was greater in cases
<60 years (median: 28.0 days, 95%CI: 26-30) than those ≥60
years (median: 19.0 days, 95%CI: 12-27). Forty-five percent of cases
were from a workplace cluster. TVC for workplace cluster versus
non-workplace cluster cases was 33.0, (95%CI: 31-34) versus 20.0,
(95%CI: 18-22) days. Conclusion: Median TVC was 28 days and
was influenced by age, sex, clinical severity and time of testing.
Future studies may be useful to clarify these differences.
The Ocean System Pathways (OSPs): a new scenario and simulation framework to investigate the future of the world fisheries
Authors: Maury Olivier , Tittensor Derek , Eddy Tyler , Allison Eddie , Bari Tarub , Barrier Nicolas , Campling Liam , Cheung William , Frieler Katja , Fulton Beth , Guillotreau Patrice , Heneghan Ryan , Lam Vicky , Leclère David , Lengaigne Matthieu , Lotze-Campen Hermann , Novaglio Camilla , Ortega-Cisneros Kelly , Schewe Jacob , Shin Yunne-Jai , Sloterdijk Hans , Squires Dale , Sumaila Rashid , Tidd Alexander , Ruijven Bas van , Blanchard Julia L.
Published: May 2024

The Fisheries and Marine Ecosystems Model Intercomparison Project
(FishMIP) has dedicated a decade to unravelling the future impacts of
climate change on marine animal biomass. FishMIP is now preparing a new
simulation protocol to assess the combined effects of both climate and
socio-economic changes on marine fisheries and ecosystems. This protocol
will be based on the Ocean System Pathways (OSPs), a new set of
socio-economic scenarios derived from the Shared Socioeconomic Pathways
(SSPs) widely used by the Intergovernmental Panel on Climate Change
(IPCC). The OSPs extend the SSPs to the economic, governance, management
and socio-cultural contexts of large pelagic, small pelagic,
benthic-demersal and emerging fisheries, as well as mariculture.
Comprising qualitative storylines, quantitative model driver pathways
and a “plug-in-model” framework, the OSPs will enable a heterogeneous
suite of ecosystem models to simulate fisheries dynamics in a
standardised way. This paper introduces this OSP framework and the
simulation protocol that FishMIP will implement to explore future ocean
social-ecological systems holistically, with a focus on critical issues
such as climate justice, global food security, equitable fisheries,
aquaculture development, fisheries management, and biodiversity
conservation. Ultimately, the OSP framework is tailored to contribute to
the synthesis work of the IPCC. It also aims to inform ongoing policy
processes within the United Nations Food and Agriculture Organisation
(FAO). Finally, it seeks to support the synthesis work of the
Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem
Services (IPBES), with a particular focus on studying pathways relevant
for the United Nations Convention on Biological Diversity (CBD).
An Integrated Global-to-Regional Scale Workflow for Simulating Climate Change Impacts on Marine Ecosystems
Authors: Ortega-Cisneros Kelly , Arcos L. Denisse Fierro , lindmark Max , Novaglio Camilla , Woodworth-Jefcoats Phoebe , Eddy Tyler , Coll Marta , Fulton Beth , Oliveros-Ramos Ricardo , Reum Jonathan Charles , Shin Yunne-Jai , Bulman Catherine M , Capitani Leonardo , Datta Samik , Murphy Kieran , Rogers Alice , Shannon Lynne , Whitehouse George A , Adekoya Ezekiel , Dias Beatriz , Fuster Alba , Hansen Cecilie , Husson Berengere , McGregor Vidette , Morell Alaia , Luna Hem-Nalini Morzaria , Ouled-Cheikh Jazel , Ruzicka Jim , Steenbeek Jeroen Gerhard , Stollberg Ilaria , Subramaniam Roshni , Tulloch Vivitskaia , Bryndum-Buchholz Andrea , Harrison Cheryl Shannon , Heneghan Ryan , Maury Olivier , Schewe Jacob , Tittensor Derek , Townsend Howard , Blanchard Julia L.
Published: May 2024

As the urgency to evaluate the impacts of climate change on marine
ecosystems increases, there is a need to develop robust projections and
improve the uptake of ecosystem model outputs in policy and planning.
Standardising input and output data is a crucial step in evaluating and
communicating results, but can be challenging when using models with
diverse structures, assumptions, and outputs that address
region-specific issues. We developed an implementation framework and
workflow to standardise the climate and fishing forcings used by
regional models contributing to the Fisheries and Marine Ecosystem Model
Intercomparison Project (FishMIP) and to facilitate comparative analyses
across models and a wide range of regions, in line with the FishMIP 3a
protocol. We applied our workflow to three case study areas-models: the
Baltic Sea Mizer, Hawai’i-based Longline fisheries therMizer, and the
southern Benguela ecosystem Atlantis marine ecosystem models. We then
selected the most challenging steps of the workflow and illustrated
their implementation in different model types and regions. Our workflow
is adaptable across a wide range of regional models, from non-spatially
explicit to spatially explicit and fully-depth resolved models and
models that include one or several fishing fleets. This workflow will
facilitate the development of regional marine ecosystem model ensembles
and enhance future research on marine ecosystem model development and
applications, model evaluation and benchmarking, and global-to-regional
model comparisons.
Estresse organizacional:
Authors: Zarife Pricila de Sousa , Paz Maria das Graças Torres da
Published: May 2024

A literatura sobre estresse ocupacional é tradicionalmente marcada pelo foco em aspectos da tarefa ou ocupação do trabalhador, negligenciando estressores organizacionais. Este artigo buscou propor um conceito, desenvolver e apresentar evidências de validade de uma escala de estresse envolvendo exclusivamente características organizacionais como potencialmente estressoras. Dois estudos quantitativos foram realizados. No primeiro estudo, a versão inicial da Escala de Estresse Organizacional (EEO) foi submetida a análise de juízes e semântica, totalizando 60 itens. A EEO foi aplicada presencialmente em 454 trabalhadores e submetida a análise fatorial exploratória. No segundo estudo, a versão resultante da EEO foi aplicada presencialmente em 501 trabalhadores e submetida a análise fatorial confirmatória. O primeiro estudo revelou uma estrutura com quatro fatores: decisões organizacionais, suporte, incentivo à competição e entraves ao crescimento profissional, e 32 itens. O segundo estudo indicou um instrumento com 25 itens e os fatores supracitados, apresentando índices satisfatórios de ajuste (χ2/gl=2,95, RMSEA=0,06, TLI=0,91, CFI=0,92 e SRMR=0,04). Os estudos apresentaram resultados promissores, propondo um novo conceito e um instrumento para auxiliar no diagnóstico organizacional e fomentar estudos para promoção de organizações mais saudáveis e produtivas.
Self-Concept Priming and Message Framing As Strategies for Improving Individuals’ Compliance: A Case Study of Bicultural Taxpayers’ Tip Reporting
Authors: Stuart Andrew C. , Riley Tracey J. , Nolder Christine J.
Published: May 2024

This study investigates the efficacy of two strategies, active self-concept priming and message framing, designed to encourage standard-compliant behavior. We prime 82 bicultural U.S. taxpayers from a collectivist culture through informational videos to activate either an individualist or collectivist self-concept. The message is framed to match (versus not match) the primed self-concept. Results reveal an ordinal interaction where participants primed with a collectivist self-concept have higher tax compliance than those primed with an individualist self-concept, and the highest compliance occurs when the message has a relational focus (i.e., collectivist prime match) compared to a self-focus (i.e., individualist prime match). Supplemental analysis suggests that raising the salience of the collectivist-self over the individualist-self indirectly affects taxpayers’ intentions to comply through the mediator of taxpayers’ attitudes. The findings highlight the potential of behavioral priming as a low-cost strategy for boosting tax revenues that fund services that benefit the public interest at large.

Data Availability: Data are available from the authors upon request.
Evolution of Research Streams and Future Research Directions in Accounting Education: Quantitative Systematic Literature Review
Authors: Cao June , Kristanto Ari Budi , Gu ZhanZhong
Published: May 2024

This study comprehensively analyzes the landscape of accounting education research and constructs the agenda for future studies. We are specifically interested in investigating the current state of accounting education research and identifying areas that require further attention for its development. We employ a quantitative systematic literature review focusing on 673 academic articles from top-tier accounting journals. The study applies various bibliometric analyses, including co-citation, bibliographic coupling, keyword co-occurrence, topic burstiness, and thematic mapping, using HistCite, VOSviewer, CiteSpace, and R Bibliometrix software. Through rigorous examination, we identify three prominent research streams: (1) accounting pedagogy, (2) competencies, and (3) ethics. Furthermore, each stream discusses specific distinctive themes. This study suggests future investigations on leveraging the accounting education role in pursuing environmental sustainability and embracing technology to improve student engagement in post-pandemic learning.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: M49; I20; I23.
Outlier Detection in Auditing: Integrating Unsupervised Learning within a Multilevel Framework for General Ledger Analysis
Authors: Wei Danyang , Cho Soohyun , Vasarhelyi Miklos A. , Te-Wierik Liam
Published: May 2024

Auditors traditionally use sampling techniques to examine general ledger (GL) data, which suffer from sampling risks. Hence, recent research proposes full-population testing techniques, such as suspicion scoring, which rely on auditors’ judgment to recognize possible risk factors and develop corresponding risk filters to identify abnormal transactions. Thus, when auditors miss potential problems, the related transactions are not likely to be identified. This paper uses unsupervised outlier detection methods, which require no prior knowledge about outliers in a dataset, to identify outliers in GL data and tests whether auditors can gain new insights from those identified outliers. A framework called the Multilevel Outlier Detection Framework (MODF) is proposed to identify outliers at the transaction level, account level, and combination-by-variable level. Experiments with one real and one synthetic GL dataset demonstrate that the MODF can help auditors to gain new insights about GL data.

Data Availability: The real dataset used in the experiment is not publicly available due to privacy policies.

JEL Classifications: M410, M42.
The Effect of City-Level Sugar-Sweetened Beverage Taxes on Longitudinal HbA1c and Incident Diabetes in Adults With Prediabetes
Authors: Lee Catherine , Sidell Margo A. , Young Deborah Rohm , Hedderson Monique M. , Cohen Deborah A. , Liu Emily F. , Barton Lee J. , Falbe Jennifer , Inzhakova Galina , Sridhar Sneha , Voorhees Allison C. , Han Bing
Published: May 2024

OBJECTIVE

Prediabetes, which is a condition characterized by higher-than-normal blood glucose levels that are under the threshold for diabetes, impacts over one-third of U.S. adults. Excise taxes on sugar-sweetened beverages (SSBs) are a proposed policy intervention to lower population consumption of SSBs and generate revenue to support health-related programs, thus potentially delaying or preventing the development of diabetes in individuals with prediabetes. We leveraged data from Kaiser Permanente in California to examine the impact of SSB taxes in California on individual-level mean HbA1c levels and rates of incident diabetes.

RESEARCH DESIGN AND METHODS

We compared two outcomes, mean HbA1c levels and rates of incident diabetes, among a matched cohort of adults with prediabetes who lived and did not live in SSB excise tax cities, using outcomes collected in the 6 years prior and 4 years following SSB tax implementation. We used multivariable linear mixed effects models to analyze longitudinal mean HbA1c and discrete-time survival models for incident diabetes.

RESULTS

We included 68,658 adults in the analysis. In adjusted models, longitudinal mean HbA1c was 0.007% (95% CI 0.002, 0.011) higher in the tax cities compared with control individuals; while the estimated difference was statistically significant, it was not clinically significant (HbA1c <0.5%). There was no significant difference in the risk of incident diabetes between individuals living in tax and control cities.

CONCLUSIONS

We found no clinically significant association between SSB taxes and either longitudinal mean HbA1c or incident diabetes among adults with prediabetes in the 4 years following SSB tax implementation.
Medical Assistant Health Coaching for Type 2 Diabetes in Primary Care: Results from a Pragmatic, Cluster-Randomized Controlled Trial
Authors: Fortmann Addie L. , C. Soriano Emily , C. Gallo Linda , L. Clark Taylor , R. Spierling Bagsic Samantha , Sandoval Haley , A. Jones Jennifer , Roesch Scott , Gilmer Todd , Schultz James , Bodenheimer Thomas , Philis-Tsimikas Athena
Published: May 2024

Objective. This cluster (clinic-level) randomized controlled trial compared medical assistant health coaching (MAC) to usual care (UC) among at-risk adults with type 2 diabetes in two diverse, real-world primary care environments: A Federally Qualified Health Center (FQHC; Neighborhood Healthcare) and a large, non-profit, private insurance-based health system (Scripps Health). Research Design and Methods. N=600 adults with type 2 diabetes and ≥1 of the following in the last 90 days were enrolled: HbA1c ≥8% and/or low-density lipoprotein cholesterol (LDL-C) ≥100mg/dL and/or systolic blood pressure (SBP) ≥140mm/Hg. Participants at MAC clinics received in-person and telephone self-management support from a specially trained MA health coach for 12 months. Electronic medical records were used to examine clinical outcomes in the overall sample. Behavioral and psychosocial outcomes were evaluated in a subsample (n=300). Results. All clinical outcomes improved significantly over one year in the overall sample (ps<.001). The reduction in HbA1c was significantly greater in the MAC vs. UC group (unstandardized Bint=-0.06, p=.002). A significant time by group by site interaction showed MAC to also achieve greater improvements in LDL-C than UC at Neighborhood Healthcare relative to Scripps Health (Bint=-1.78 vs. 1.49, ps<.05). No other statistically significant effects were observed. Conclusions. This was the first large-scale, pragmatic trial supporting the real-world effectiveness of MA health coaching for type 2 diabetes in US primary care settings. Findings suggest that this team-based approach may be particularly effective in improving diabetes outcomes in FQHC settings.