bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing Neighborhood Walkability Based on Usage Characteristics of Amenities under Chinese Metropolises Context
Authors: Xia Zelong , Li Hao , Chen Yuehong
Published: October 2018

In the age of rapid motorization, walking, as both a green travelling mode and the most common form of daily physical activity, has been given increasing attention in Chinese metropolises. Walkability describes the extent to which a neighborhood environment is walking-friendly and recently has been regarded as a potential impetus for inflated housing prices. In this paper, we develop a walkability measurement model considering residents’ usage characteristics of the amenity, which incorporates three key factors: (1) amenity usage frequency; (2) amenity selection diversity; (3) the distance decay effect. Accordingly, we employ the proposed method to the case of Nanjing City and identify a clear spatial pattern of spatial heterogeneity in walkability among the 4143 dwelling areas within it. The experimental results suggest that the distribution of the residential walkability score varied greatly within Nanjing. It can be seen that dwelling areas with a high walkability score were clustered in the urban central regions and most dwelling areas showed a low walkability. Then, we utilized the hedonic price model to explore the correlation between neighborhood walkability and housing prices. The results show that the effects of community walkability on housing prices were statistically significant in Nanjing. Thus, we can infer that high walkability communities generally have concentrated rich amenity resources, and consequently have high property values.
Mandatory Sustainability Reporting in Germany: Does Size Matter?
Authors: Bergmann Alexander , Posch Peter
Published: October 2018

This article studies how German firms evaluate a recent national corporate social responsibility (CSR) law based on a European Union directive and the burden they expect regarding their organizational responsibilities due to mandatory sustainability reporting. One hundred and fifty-one firms of different sizes directly or indirectly affected by the law are included in the survey and their responses empirically analyzed using two-tailed t-tests and simple linear regression. Anchoring the discussion in stakeholder theory and the small and medium-sized enterprise (SME) literature while considering large-firm idiosyncrasies, the results show differing effects on SMEs and large firms as well as firms which are directly and indirectly affected. Findings show that firm size only matters for the evaluation of the law by directly affected firms, while size does not matter in the case of indirectly affected firms. Possible moderators of this evaluation are grounded in the resource-based theory and formalization of CSR. This article contributes to the understanding of when firm size matters in the case of mandatory sustainability reporting and underlines the role of organizational resources and capabilities as well as the special position of SMEs.
Model-Based Exploration of Co-Creation Efforts: The Case of Solar Photovoltaics (PV) in Skåne, Sweden
Authors: Selvakkumaran Sujeetha , Ahlgren Erik O.
Published: October 2018

Co-creation in the societal sphere is becoming important in many parts of the world. However, empirical analysis of co-creation in local energy transitions has been understudied. This paper aims to contribute to the field of local energy transitions by integrating a model-based approach with the municipal co-creation efforts in a local energy transition setting. The study uses a mixed-methods approach, with both quantitative and qualitative methods underpinning the approach. A System Dynamics (SD) model is built to analyse the feedback loops created by the co-creation efforts of the municipalities in Skåne, Sweden to increase the uptake of household solar photovoltaics. Simultaneously, the model is conceptualized and built in coordination with the municipality actors, and qualitative validation provided by them. An iterative process is implemented, consisting of three steps: interaction with the municipality actors (MAs), developing the causal relationships between the model variables and model development. The suggestions and discussions with the MAs were very useful in understanding the social factors and processes which help in the diffusion of a technologically innovative product, such as solar PV. The MAs said that they found the explanation of the modelling variables useful in undertaking the co-creation efforts.
Sustainable Land-Use, Wildfires, and Evolving Local Contexts in a Mediterranean Country, 2000–2015
Authors: Marchi Maurizio , Chianucci Francesco , Ferrara Carlotta , Pontuale Giorgio , Pontuale Elisa , Mavrakis Anastasios , Morrow Nathan , Rossi Fabrizio , Salvati Luca
Published: October 2018

Socioeconomic conditions and land management choices combine to affect changes in long-term wildfire regimes in Mediterranean-type ecosystems. Identification of specific drivers and dynamics at the local level is needed to inform land resource planning and to enhance wildfire management efficiency. Therefore, investigating feedback relationships between wildfire and socioeconomic conditions at local and regional scales can reveal consistency in spatial and temporal patterns influencing wildfire frequency, intensity, and severity. This study assessed long-term wildfire characteristics in Greece—one of the most fire-prone countries in Europe—over two consecutive time periods characterized by economic expansion (2000–2007) and recession (2008–2015). An integrated, multivariate statistical approach was implemented to assess the latent relationship between socioeconomic forces and localized wildfire regime indicators. Changes in the number of fires at the wildland–urban interface and duration of wildfires were consistent with expectations. Observed changes in the size of fires showed mixed results. Empirical findings of this study indicate analysis of wildfire regimes that takes into account both the socioeconomic and environmental factors in the overall territorial context of Mediterranean-type ecosystems, at both regional and local scale, may prove informative for the design of wildfire prevention measures in Greece.
A Conceptual Tool for the Implementation of the Circular Economy Emissions Reuse Closed Loops through Process Equipment
Authors: Ridaura Gregorio , Llorens-Cervera Sonia , Carrillo Carmen , Buj-Corral Irene , Riba-Romeva Carles
Published: October 2018

Nowadays industry is immersed in a transition to the Circular Economy (CE) as a way to achieve resource efficiency in production processes. However, the implementation of CE closed loops is still in an initial phase and it focuses mainly on the recycling of components of products instead of the reuse of emissions. The purpose of this study is to explore the possibility of accelerating the transition of the CE in production processes through a conceptual tool that allows the possibility of evaluating the reuse of emissions between the equipment involved in a process. The Environmental Analysis of Relations of Coexistence of the Equipment (EARC) tool is a novelty in the implementation of the CE emissions reuse closed loops at the company level. The EARC tool focuses on the identification and analysis of the equipment involved in a process and in the material inputs and emissions outputs of each of its operations with the objective of evaluating the possibility of reusing emissions among them. This paper presents a conceptual tool as the basis for the development of a redesign methodology for the reuse of emissions in production processes with the objective of reducing the consumption of resources and the generation of emissions as well as the reduction of production costs.
Shari’ah-Compliant Finance: A Possible Novel Paradigm for Green Economy Investments in Italy
Authors: Campisi Domenico , Gitto Simone , Morea Donato
Published: October 2018

In Italy, the dramatic reduction of government incentives has caused a decrease of investments in the renewable energy sector. For this reason, it is necessary to rethink funding techniques, extending the analysis to different cultural and financial models. In this paper, we study the incentive-dependency of an Italian case study in the wind energy sector in order to reach grid parity, comparing the obtained results with those of Islamic finance and conventional finance. In particular, we propose that Sukuk Islamic finance instruments be used for the realization of real assets in Shari’ah-compliant finance that prohibits interest rates, as in conventional financial markets, and we present the building cost thresholds necessary to achieve grid parity. Our results highlight the importance of incentives and the applicability of the use of Sukuk instruments for sustainable investments in the wind energy sector, which is crucial in the framework of current efforts against climate change as well as efforts to reduce greenhouse gas emissions.
From Culture 1.0 to Culture 3.0: Three Socio-Technical Regimes of Social and Economic Value Creation through Culture, and Their Impact on European Cohesion Policies
Authors: Sacco Pier Luigi , Ferilli Guido , Tavano Blessi Giorgio
Published: October 2018

We develop a new conceptual framework to analyze the evolution of the relationship between cultural production and different forms of economic and social value creation in terms of three alternative socio-technical regimes that have emerged over time. We show how, with the emergence of the Culture 3.0 regime characterized by novel forms of active cultural participation, where the distinction between producers and users of cultural and creative contents is increasingly blurred, new channels of social and economic value creation through cultural participation acquire increasing importance. We characterize them through an eight-tier classification, and argue on this basis why cultural policy is going to acquire a central role in the policy design approaches of the future. Whether Europe will play the role of a strategic leader in this scenario in the context of future cohesion policies is an open question.
Botulinum Toxin Injections and Electrical Stimulation for Spastic Paresis Improve Active Hand Function Following Stroke
Authors: Lee Jong-Min , Gracies Jean-Michel , Park Si-Bog , Lee Kyu Hoon , Lee Ji Yeong , Shin Joon-Ho
Published: October 2018

Botulinum toxin type A (BTX-A) injections improve muscle tone and range of motion (ROM) among stroke patients with upper limb spasticity. However, the efficacy of BTX-A injections for improving active function is unclear. We aimed to determine whether BTX-A injections with electrical stimulation (ES) of hand muscles could improve active hand function (AHF) among chronic stroke patients. Our open-label, pilot study included 15 chronic stroke patients. Two weeks after BTX-A injections into the finger and/or wrist flexors, ES of finger extensors was performed while wearing a wrist brace for 4 weeks (5 days per week; 30-min sessions). Various outcomes were assessed at baseline, immediately before BTX-A injections, and 2 and 6 weeks after BTX-A injections. After the intervention, we noted significant improvements in Box and Block test results, Action Research Arm Test results, the number of repeated finger flexions/extensions, which reflect AHF, and flexor spasticity. Moreover, significant improvements in active ROM of wrist extension values were accompanied by marginally significant changes in Medical Research Council wrist extensor and active ROM of wrist flexion values. In conclusion, BTX-A injections into the finger and/or wrist flexors followed by ES of finger extensors improve AHF among chronic stroke patients.
Using the Marine Rotifer Brachionus plicatilis as an Endpoint to Evaluate Whether ROS-Dependent Hemolytic Toxicity Is Involved in the Allelopathy Induced by Karenia mikimotoi
Authors: Li Yuanyuan , Yu Jianfei , Sun Tianli , Liu Chunchen , Sun Yu , Wang You
Published: October 2018

The toxic effects of the typically noxious bloom-forming dinoflagellate Karenia mikimotoi were studied using the allelopathic experimental system under controlled laboratory conditions. The potency of intact cell suspensions with whole cells, cell-free culture filtrate in different growth phases, and lysed cells with ultrasonication were compared, and the growth and reproduction of the marine rotifer Brachionus plicatilis were used as endpoints to evaluate toxic differences. The intact cell suspension resulted the most significant growth inhibition, including lethality, on the growth of B. plicatilis (p < 0.05). Lysed culture medium treated with ultrasonication and the cell-free culture filtrates at either the exponential or stationary phase exhibited limited negative impacts compared to the control according to changes in the population growth rate (r) and survival rate (p > 0.05). Reproduction presented a similar tendency to change, and the number of eggs produced per individual, as well as spawning period decreased in the whole cell and lysed cell suspensions. The key parameters in the lift table include the net reproductive rate (R0) and the intrinsic rate of increase (rm), which were more sensitive to treatment and were significantly suppressed compared to that of the control. The addition of the ROS inhibitor N-acetylcysteine (NAC) could not change the growth or reproduction patterns. Moreover, substantial hemolytic toxicity was found in the treatment of the intact cell suspension (p < 0.05), while limited toxicity was found in other treatments compared to that of the control. K. mikimotoi was speculated to secrete allelopathic substances onto the cell surface, and direct cell contact was necessary for allelopathic toxicity in B. plicatilis. Reactive oxygen species (ROS)-independent hemolytic toxicity was assumed to be the explanation for what was observed.
Investigation into Cellular Glycolysis for the Mechanism Study of Energy Metabolism Disorder Triggered by Lipopolysaccharide
Authors: Zhang Ruyuan , Ji Jian , Blaženović Ivana , Pi Fuwei , Wang Tingwei , Zhang Yinzhi , Sun Xiulan
Published: October 2018

Lipopolysaccharide (LPS) is the main virulence factor of Gram-negative bacteria, which can incite inflammation in tissues by inducing cells to secrete a variety of proinflammatory mediators, including cytokines, chemokines, interleukins, and prostaglandins. Herein, we chose LPS as an inducer to establish an inflammatory model of HeLa cells, and explored the effects of LPS on energy metabolism. We treated HeLa cells with different concentrations (0, 0.4, 1.0, 2.0, 4.0, and 6.0 μg/mL) of LPS for 24 h, and explored its effects on intercellular adenosine triphosphate (ATP) levels, intercellular nitrous oxide (NO) content, mitochondrial functions, and enzyme activities related to energy metabolism. Furthermore, we used metabonomics to study the metabolites that participated in energy metabolism. We found a positive correlation between LPS concentrations and intracellular ATP levels. In addition, LPS increased intracellular NO production, altered mitochondrial functions, strengthened glycolytic enzyme activities, and changed metabolites related to energy metabolism. Hence, in this study, we showed that LPS can strengthen energy metabolism by enhancing glycolysis, which could be used as an early diagnostic biomarker or a novel therapeutic target for inflammation-associated cancers.
The Interaction Dynamics of Two Potato Leafroll Virus Movement Proteins Affects Their Localization to the Outer Membranes of Mitochondria and Plastids
Authors: DeBlasio Stacy L. , Xu Yi , Johnson Richard S. , Rebelo Ana Rita , MacCoss Michael J. , Gray Stewart M. , Heck Michelle
Published: October 2018

The Luteoviridae is an agriculturally important family of viruses whose replication and transport are restricted to plant phloem. Their genomes encode for four proteins that regulate viral movement. These include two structural proteins that make up the capsid and two non-structural proteins known as P3a and P17. Little is known about how these proteins interact with each other and the host to coordinate virus movement within and between cells. We used quantitative, affinity purification-mass spectrometry to show that the P3a protein of Potato leafroll virus complexes with virus and that this interaction is partially dependent on P17. Bimolecular complementation assays (BiFC) were used to validate that P3a and P17 self-interact as well as directly interact with each other. Co-localization with fluorescent-based organelle markers demonstrates that P3a directs P17 to the mitochondrial outer membrane while P17 regulates the localization of the P3a-P17 heterodimer to plastids. Residues in the C-terminus of P3a were shown to regulate P3a association with host mitochondria by using mutational analysis and also varying BiFC tag orientation. Collectively, our work reveals that the PLRV movement proteins play a game of intracellular hopscotch along host organelles to transport the virus to the cell periphery.
Assessment of Precipitation Simulations in Central Asia by CMIP5 Climate Models
Authors: Ta Zhijie , Yu Yang , Sun Lingxiao , Chen Xi , Mu Guijin , Yu Ruide
Published: October 2018

The Coupled Model Intercomparison Project Phase 5 (CMIP5) provides data, which is widely used to assess global and regional climate change. In this study, we evaluated the ability of 37 global climate models (GCMs) of CMIP5 to simulate historical precipitation in Central Asia (CA). The relative root mean square error (RRMSE), spatial correlation coefficient, and Kling-Gupta efficiency (KGE) were used as criteria for evaluation. The precipitation simulation results of GCMs were compared with the Climatic Research Unit (CRU) precipitation in 1986–2005. Most models show a variety of precipitation simulation capabilities both spatially and temporally, whereas the top six models were identified as having good performance in CA, including HadCM3, MIROC5, MPI-ESM-LR, MPI-ESM-P, CMCC-CM, and CMCC-CMS. As the GCMs have large uncertainties in the prediction of future precipitation, it is difficult to find the best model to predict future precipitation in CA. Multi-Model Ensemble (MME) results can give a good simulation of precipitation, and are superior to individual models.
A Theoretically Derived Probability Distribution of Scour
Authors: Manfreda Salvatore , Link Oscar , Pizarro Alonso
Published: October 2018

Based on recent contributions regarding the treatment of unsteady hydraulic conditions in the state-of-the-art scour literature, theoretically derived probability distribution of bridge scour is introduced. The model has been derived assuming a rectangular hydrograph shape with a given duration, and a random flood peak, following a Gumbel distribution. A model extension for a more complex flood event has also been presented, assuming a synthetic exponential hydrograph shape. The mathematical formulation can be extended to any flood-peak probability distribution. The aim of the paper is to move forward the current approaches adopted for the bridge design, by coupling hydrological, hydraulic, and erosional models, in a mathematical closed form. An example of the application of the proposed distribution has been included with the aim to provide a guidance for the parameters estimation.
Estimation of River Management Flow Considering Stream Water Deficit Characteristics
Authors: Sung Jang Hyun , Seo Seung Beom
Published: October 2018

South Korea endured extreme drought through 2015 and 2016. This hydrological drought led to a socio-economic drought which is a restriction on stream water use. Previous studies have explored streamflow drought using a threshold level based on flow duration curves, but streamflow drought does not necessarily lead to stream water deficit, which is related to water demand. Therefore, this study introduced a threshold for stream water deficit in South Korea, which is termed as river management flow, and was applied to Geum River Basin where a severe drought recently occurred. The stream water coordination council has restricted the use of stream water to cope with the stream water deficit. The deficit characteristics for the upstream and downstream river management flow should be similar in order to ensure the feasibility of stream water restrictions. Thus, upstream and downstream river management flows, which reproduced similar deficit characteristics to those of the reference site, were estimated. The deficit characteristics of Bugang and Gyuam were estimated from their river management flows for the 2015 drought and were comparable to those of Gongju. We expect this study to minimize the conflict between upstream and downstream water users in future.
Response of the Meltwater Erosion to Runoff Energy Consumption on Loessal Slopes
Authors: Wang Tian , Li Peng , Hou Jingming , Li Zhanbin , Ren Zongping , Cheng Shengdong , Xu Guoce , Su Yuanyi , Wang Feichao
Published: October 2018

Soil properties are influenced by freeze-thaw, which in turn influences soil erosion. Despite this, only a few studies have investigated the impacts on soil hydrodynamic processes. The objective of this study was to evaluate the impact of soil freezing conditions on runoff, its energy consumption, and soil erosion. A total of 27 laboratory-concentrated meltwater flow experiments were performed to investigate the soil erosion rate, the runoff energy consumption, and the relationship between the soil erosion rate and runoff energy consumption by concentrated flow under combinations of three flow rates (1, 2, and 4 L/min) and three soil conditions (unfrozen, shallow-thawed, and frozen). The individual and combined effects of soil condition, flow rate, and runoff energy consumption on the soil erosion rate were analyzed. For the same flow rate, the shallow-thawed and frozen slope produced mean values of 3.08 and 4.53 times the average soil erosion rates compared to the unfrozen slope, respectively. The number of rills in the unfrozen soil slope were 4, 3, and 2 under the flow rate of 1, 2, and 4 L/min, respectively. The number of rills in the thawed-shallow and frozen soil slope were all 1 under the flow rate of 1, 2, and 4 L/min. The rill displayed disconnected distribution patterns on the unfrozen slope, but a connected rill occurred on the shallow-thawed and frozen slopes. The average rill width on unfrozen, thawed-shallow, and frozen soil slopes increased by 1.87 cm, 4.38 cm, and 1.68 cm as the flow rate increased from 1 L/min to 4 L/min. There was no significant difference in the rill length on the frozen slope under different flow rates (p > 0.05). The runoff energy consumption ranged from unfrozen > shallow-thawed > frozen slopes at the same flow rate. The soil erosion rate had a linear relationship with runoff energy consumption. The spatial distribution of the runoff energy implied that soil erosion was mainly sourced from the unfrozen down slope, shallow-thawed upper slope, and frozen full slope.
The Effect of Organic Carbon Addition on the Community Structure and Kinetics of Microcystin-Degrading Bacterial Consortia
Authors: Manheim Derek , Cheung Yuen-Ming , Jiang Sunny
Published: October 2018

Microcystin (MC), a hepatotoxin that is associated with cyanobacterial blooms in freshwater lakes, threatens the quality of drinking water resources. Biodegradation of MC using biofiltration is emerging as a cost-effective solution for drinking water treatment. This study reports isolation of five MC-degrading microbial consortia and investigation of their community structure and kinetics in the presence or absence of a readily-bioavailable organic carbon source. The results indicated that the presence of a bioavailable organic carbon source caused: (1) the proliferation of community members previously unobserved in each consortium cultured without ethanol; (2) a shift in abundance of representative taxa; (3) a fluctuation in genera affiliated with MC-biodegradation; and, (4) a unique response in simulated diversity among consortia. These changes to each microbial consortium were paralleled by a significant decline in MC degradation kinetics. Overall, this study highlights the importance of integrating environmental conditions into the design and operation of biofiltration systems for MC biodegradation.
North Sea Ecosystem-Scale Model-Based Quantification of Net Primary Productivity Changes by the Benthic Filter Feeder Mytilus edulis
Authors: Lemmen Carsten
Published: October 2018

Blue mussels are among the most abundant bivalves in shallow water along the German coasts. As filter feeders, a major ecosystem service they provide is water filtration and the vertical transfer of suspended organic and attached inorganic material to the sea floor. Laboratory and field studies previously demonstrated that blue mussels can remove large quantities of plankton from the surrounding water. I here perform numerical experiments that investigate the effect of filtration at the scale of an entire coastal sea—the southern North Sea. These experiments were performed with a state-of-the-art bentho-pelagic coupled hydrodynamic and ecosystem model and used a novel reconstruction of the benthic biomass distribution of blue mussels. The filtration effect was assessed as the simulated change in net primary productivity caused by blue mussels. In shallow water, filtration takes out up to half of the entire annual primary productivity; it is negligible in offshore waters. For the entire basin, the filtration effect is 10%. While many ecosystem models have a global parameterization for filter feeders, the coastal gradient in the filtration effect is usually not considered; our research demonstrates the importance of including spatially heterogeneous filtration in coupled bentho-pelagic ecosystem models if we want to better understand the spatial patterns in shallow water coastal systems.
Project AMIGA: Distance and Metallicity Gradients along Andromeda’s Giant Southern Stream from the Red Clump∗
Authors: Cohen Roger E. , Kalirai Jason S. , Gilbert Karoline M. , Guhathakurta Puragra , Peeples Molly S. , Lehner Nicolas , Brown Thomas M. , Bianchi Luciana , Barger Kathleen A. , O’Meara John M.
Published: October 2018

The Giant Southern Stream (GSS) of M31, a keystone signature of a major accretion event, yields crucial constraints on M31 formation and evolution models. Currently, our understanding of the GSS, in terms of both its geometry and its chemistry, results from either wide-field imaging probing only a few magnitudes below the red giant branch tip, or deep imaging or spectroscopy of isolated regions. Here, we take an alternative approach, using Hubble Space Telescope (HST) imaging to characterize the horizontal branch red clump (RC) using unbinned maximum likelihood fits to luminosity functions from observed color–magnitude diagrams. Comparing the RC mean magnitude across three fields at projected distances of 21, 52, and 80 kpc from M31, we find a line-of-sight distance gradient identical to recent literature measurements in fields along the core. We also find tentative evidence that the line-of-sight distance dispersion increases with projected distance from M31. Meanwhile, the metallicity in the 52 kpc field westward of the GSS core is at least as high as that in the 21 kpc GSS core field, and the peak colors of the RC in these two fields imply identical metallicities to within 0.2 dex. We discuss implications for distance and metallicity gradients both along and perpendicular to the GSS in the context of recent ground-based photometric and spectroscopic results, including evidence for a dropoff in metallicity moving westward from the GSS, as well as prospects for further constraining stellar populations in the vicinity of the GSS.
A review of the genus Apronopa van Achterberg (Hymenoptera, Braconidae, Alysiinae) with a key to species
Authors: Peris Felipo Francisco Javier , Belokobylskij Sergey A.
Published: October 2018

A review of the genus Apronopa van Achterberg, 1980 with illustrated re-descriptions of the known species and a key for their identification is provided.
Designing for deep learning in the context of digital and social media
Authors: Gee James-Paul , Esteban-Guitart Moisés
Published: October 2018

There is today a great deal of controversy over digital and social media. Even leaders in the tech industry are beginning to decry the time young people spend on smartphones and social networks. Recently, the World Health Organization proposed adding “gaming disorder” to its official list of diseases, defining it as a pattern of gaming behavior so severe that it takes “precedence over other life interests”. At the same time, many others have celebrated the positive properties of video games, social media, and social networks. This paper argues that a deeper understanding of human beings is needed to design for deep learning. For the purposes of this study “design for deep learning” means helping people matter and find meaning in ways that make them and others healthy in mind and body, while improving the state of the world for all living things, with due respect for truth, sensation, happiness, imagination, individuality, diversity, and the future. In particular, fifteen features related to human nature are suggested based on recent scientific developments to answer the question: What is a human being? Consequently, proposals that are linked to learning and transformation, as well as social improvement, should fit with the ways in which humans, as specific sorts of biological and social creatures, learn best (or can learn at all) and can change for the better.

En la actualidad existe una nutrida controversia en relación a los medios de comunicación sociales y digitales que ha llevado, incluso, a censurar la utilización de las redes sociales y los móviles por parte de líderes en la industria tecnológica. En este sentido, la Organización Mundial para la Salud ha propuesto añadir el «desorden del juego» a su listado de enfermedades, definiéndolo como un modelo de comportamiento de juego tan severo que se impone como «preferencia sobre otros intereses». Al mismo tiempo, distintos académicos han enfatizado los aspectos positivos derivados de las redes sociales y los videojuegos. En este artículo se argumenta que es necesaria una mejor comprensión del ser humano para poder implementar lo que aquí se define como diseño para el aprendizaje profundo. El «diseño para el aprendizaje profundo» está encaminado al reconocimiento de las personas y el desarrollo de sentidos saludables, individual y colectivamente, así como la mejora, en general, del estado del mundo para todos los seres vivos, según principios de verdad, felicidad, imaginación, individualidad, diversidad y futuro. En particular, se sugieren quince características basadas en desarrollos científicos que responden a la pregunta: ¿Qué es un ser humano? Consecuentemente, propuestas vinculadas al aprendizaje y la transformación y mejora social deben ser coherentes con dichas características que permiten definir cómo las personas, en tanto que organismos biológicos y sociales, aprenden o pueden aprender óptimamente, así como cambiar para mejorar.
La lanza de Alejandro en Gortina
Authors: Antela-Bernárdez Borja
Published: October 2018

Una información recogida por Pausanias sobre la dedicatoria en Gortina de una punta de lanza que perteneció a Alejandro Magno permite considerar en detalle tanto la procedencia de la lanza como su valor curativo. El análisis nos remite, además, a las habilidades curativas de los Eácidas, y por ende, a las relaciones entre curación y poder en el mundo antiguo.
Centurions in roman epigraphy of Hispania : social relationships
Authors: López Casado Roberto
Published: October 2018

The centurion was the backbone of the Roman army. The article aims at analysing the centurion social relationships during the High Roman Empire through the epigraphic sources in Hispania. We focus on the family nucleus creation as well as the patronage relations formation as some of the core social indicators to be considered in centurions.
Cañones al óleo. una alternativa para la artillería de Cartagena de Indias a fines del siglo XVIII
Authors: Gámez Casado Manuel
Published: October 2018

El presente artículo tiene como objetivo analizar algunos de los aspectos menos conocidos de la artillería de Cartagena de Indias durante el siglo XVIII. Entre éstos, la realización de distintos experimentos sobre los cañones de hierro permitió superar los desperfectos generados por el clima mediante la utilización de un nuevo barniz. Además, se incluye un estudio sobre las aportaciones que los militares españoles realizaron para mejorar el artillado de dicha ciudad. Para ello, partiendo de anteriores publicaciones y analizando fuentes primarias, se examinarán los modelos de cañones utilizados en las fortificaciones, ahondando tanto en la relación existente entre ingeniería y artillería, como en los mecanismos de fabricación e importación del armamento desde la Península Ibérica a América.
The Use of Interactive Mobile Technology to Improve the Quality of Health Care Services in Private and Public Hospitals in Australia
Authors: Karim Shakir , Gide Ergun
Published: October 2018

The research questions, "As an Australian, can we expect fully Mobile Technology integrated health care services in Australia? Is it possible everywhere in Australia?" A healthcare system whether private or public should provide comprehensive health care services all over in Australia including countryside and CBD. In addition, the term ‘Mobile Technology integrated health care’ refers to a healthcare system designed for electronic and smart devices which can be used anytime and anywhere in the world. This research paper examines ‘how patients can access GPs, specialists, private and public hospitals in Australia’, which provide interactive Mobile Technology based health services. The research has mainly used secondary research data analysis and methods to provide a broad investigation of the issues relevant to interactive Mobile Technology and health care system in Australia, the problems, problem factors, benefits and opportunities in the health care industry. The research is subject to academic journal articles, conference proceedings, academic text books, project reports, online media articles, corporation-based documents and other appropriate information, including a technology adoption or acceptance research model for Mobile Technology integrated health care system. The preliminary stage of the research findings show that the proposed integrated Mobile Technology model can be applied to the current health care system in Australia, particularly improving patients’ smooth access to GPs, specialists, public and private hospitals. Finally, the Mobile Technology integrated health care system will ensure that the framework is user and environmentally friendly including positive and active interactions with all system functions.
Possibilities of the Subject ‘Information and Communication Technologies’ in Accustoming Primary School Students to Research Activities
Authors: Tashkenbayevna Nazgul , Kenesbaev Serik M. , Zhailauova M.K. , Elmira Uaidullakyzy , Nurzhanova S. A. , Stambekova A. S.
Published: October 2018

This article considers the issue of accustoming primary school students to research activities and basically focuses on information technology, which is the main tool for increasing cognitive activity. We define joint creative activities of teacher and student, which are carried out in seeking the solution of the unknown problem defined as an academic goal of students, and as a result of which cultural values are passed on as research activities. In this case, the teacher acts as the organiser of the forms and situations of research activity. It is insufficient for school children just to make a decision in solving the problems occurring in academic goals, the results achieved in the implementation process should be helpful for someone. From this point of view, the issue of molding a motivation, which permanently leads the student to master study-research skills, will be on the agenda.
Analysis of FHS community health agents knowledge about oral health - doi: 10.4025/actascihealthsci.v35i2.11723
Authors: Vinagre Nicole Patricia de Lima , Farias Cleysiane Gonçalves , Cardoso Débora Gomes , Alvares Luciana Dias , Gabriel Paula Moura , Amoras-Alves Ana Cláudia Braga
Published: October 2018

The community health agents (CHA) are considered health promoters in Brazilian communities teaching them about health promotion and disease prevention, including oral health. According to the Ministry of Health, CHAs must know about seven major oral health issues in Brazil. Thus, the objective of this study was to evaluate the oral health knowledge level of CHAs in the city of Belem, Pará State, Brazil. The study was based on a self-guided script, through a pre-prepared questionnaire containing 16 multiple-choice questions related to oral health knowledge. The survey was conducted with 94 agents from seven Family Health stations featuring oral health teams in Belem. It was concluded that community agents should be better prepared about oral care, as not all oral health issues were known by the CHAs oral health teams in Belem.
Food behaviors and youth obesity in Pakistan - doi: 10.4025/actascihealthsci.v35i2.11885
Authors: Hashmi Anjum , Soomro Jamil Ahmed , Saleem Khalid
Published: October 2018

The epidemic of obesity took off from about 1980 and in almost all countries has been rising inexorably ever since. Only in 1997 did world health organization accept that this was a major public health problem. It is also becoming an important public health problem among Pakistani children due to changes in life style and other factors. The increasing prevalence of childhood obesity and its concomitant health risks justify widespread efforts toward prevention. A Cross-sectional study was conducted to elaborate the various types of foods and change in eating behavior leading to abnormal weight gain among the youth. A total of 504 male and female students of class six to ten were selected through simple random sampling. Anthropometric measurements were done with calibrated instruments using the age and sex specific BMI cut off points according to World Health Organization growth reference. Results showed significant proportion of girls (86%) and boys (85%) had abnormal waist to hip ratio. The determinants of the obesity lie within the rapid changes in food intake behavior and lifestyle patterns which had a clear and significant impact on the prevalence of obesity in youth of Pakistan.
Social and economic profile of young trauma victims and alcohol addicts - doi: 10.4025/actascihealthsci.v35i2.13054
Authors: Arnauts Ivonete , Oliveira Magda Lúcia Félix
Published: October 2018

The social and economic profile of alcohol-traumatized young people and alcohol users is provided through an exploratory and transversal analysis with 10-24-year-old young people attended to at the Emergency Section of a hospital in the western region of the state of Paraná, Brazil. Data were processed by Statistica 8.0. One hundred and twelve young people were classified in three groups according to alcohol intake: trauma associated with alcoholic beverage consumption; alcohol consumers without any alcohol intake during the previous six hours; teetotalers. Alcohol trauma was predominant in male young people with complete primary schooling, family income between R$ 901 and R$ 1500, without any personal income and working regularly. Higher occurrence lay within the 15-20 years age bracket regardless of their alcohol intake pattern. Results show that young people’s social and economical profile affects the capacity of people in acknowledging and managing the dangers to which they are exposed. Interventions are relevant when the historical and social contexts are taken into account so that changes in health, disease and care processes could be enhanced.
Compliant surface after ACL reconstruction and its effects on gait - doi: 10.4025/actascihealthsci.v35i2.13528
Authors: Tellini Tamires Lisboa , Lima Karina Oliveira , Alouche Sandra Regina , Bagesteiro Leia Bernardi
Published: October 2018

Previous studies of gait analysis in patients following reconstructive anterior cruciate ligament (ACL) surgery have shown changes in kinematics, kinetics and energy patterns in the lower limb. Usually these patients perform complaint surface training during clinical treatment. The purpose of this study was to evaluate the changes in selected gait kinematic parameters following ACL reconstruction while walking on an unstable surface. We tested 16 subjects: eight patients who underwent ACL reconstruction, at four weeks after the surgical intervention; and eight healthy subjects (control group) matched by age and gender. Participants walked at a self-selected comfortable speed on an 8 m-walkway while sagittal plane kinematic data of the principal lower limb joints (hip, knee and ankle) were collected using 60-Hz cameras. We compared the joint angles under three conditions: (A) walking on stable ground, (B) walking on a foam mat (5 cm thick; 33 kg m-3 density) and (C) back at the normal ground. Results showed that ACL patients were slower and had smaller range of motion at all joints as compared to the control group under all conditions; however the repeated exposure to unstable surface may help changes in such patients. Further investigation is necessary to expand our understanding and may improve the development of more effective rehabilitation treatments.
Type 2 Innate Lymphoid Cells Impede IL-33–Mediated Tumor Suppression
Authors: Long Alan , Dominguez Donye , Qin Lei , Chen Siqi , Fan Jie , Zhang Minghui , Fang Deyu , Zhang Yi , Kuzel Timothy M. , Zhang Bin
Published: October 2018

Although a number of studies have recently explored the contribution of the adaptive immunity in IL-33–mediated antitumor effects, innate immune involvement has been poorly characterized. Utilizing Rag1−/− mice (lacking T and B lymphocytes), we show in this study that either systemic administration of recombinant IL-33 or ectopic expression of IL-33 in melanoma cells is sufficient to inhibit tumor growth independent of adaptive antitumor immunity. We have demonstrated that IL-33–mediated antitumor effects depend on expansion and activation of NK cells. Interestingly, IL-33 also promoted the expansion of active type 2 innate lymphoid cells (ILC2s) via its receptor, ST2, which in turn inhibited NK activation and cytotoxicity. This IL-33–induced ILC2 activity coincided with greater expression of the immunosuppressive ectoenzyme CD73. Removal of CD73 from ILC2s in culture with NK cells resulted in markedly increased activation levels in NK cells, offering a potential mechanism by which ILC2s might suppress NK cell–mediated tumor killing. Thus, our data reveal an important contribution of IL-33–induced ILC2 to tumor growth by weakening NK cell activation and tumor killing, regardless of adaptive immunity.
Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells
Authors: Du Samuel W. , Jacobs Holly M. , Arkatkar Tanvi , Rawlings David J. , Jackson Shaun W.
Published: October 2018

The B cell survival cytokine BAFF has been linked with the pathogenesis of systemic lupus erythematosus (SLE). BAFF binds distinct BAFF-family surface receptors, including the BAFF-R and transmembrane activator and CAML interactor (TACI). Although originally characterized as a negative regulator of B cell activation, TACI signals are critical for class-switched autoantibody (autoAb) production in BAFF transgenic mice. Consistent with this finding, a subset of transitional splenic B cells upregulate surface TACI expression and contribute to BAFF-driven autoAb. In the current study, we interrogated the B cell signals required for transitional B cell TACI expression and Ab production. Surprisingly, despite established roles for dual BCR and TLR signals in autoAb production in SLE, signals downstream of these receptors exerted distinct impacts on transitional B cell TACI expression and autoAb titers. Whereas loss of BCR signals prevented transitional B cell TACI expression and resulted in loss of serum autoAb across all Ig isotypes, lack of TLR signals exerted a more limited impact restricted to autoAb class-switch recombination without altering transitional B cell TACI expression. Finally, in parallel with the protective effect of TACI deletion, loss of BAFF-R signaling also protected against BAFF-driven autoimmunity. Together, these findings highlight how multiple signaling pathways integrate to promote class-switched autoAb production by transitional B cells, events that likely impact the pathogenesis of SLE and other BAFF-dependent autoimmune diseases.
The First Decade of Web-Based Sports Injury Surveillance: Descriptive Epidemiology of Injuries in US High School Boys' Soccer (2005–2006 Through 2013–2014) and National Collegiate Athletic Association Men's Soccer (2004–2005 Through 2013–2014)
Authors: Kerr Zachary Y. , Putukian Margot , Chang Cindy J. , DiStefano Lindsay J. , Currie Dustin W. , Pierpoint Lauren A. , Knowles Sarah B. , Wasserman Erin B. , Dompier Thomas P. , Comstock R. Dawn , Marshall Stephen W.
Published: October 2018

Context: 

The advent of Web-based sports injury surveillance via programs such as the High School Reporting Information Online system and the National Collegiate Athletic Association Injury Surveillance Program has aided the acquisition of boys' and men's soccer injury data.

Objective: 

To describe the epidemiology of injuries sustained in high school boys' soccer in the 2005–2006 through 2013–2014 academic years and collegiate men's soccer in the 2004–2005 through 2013–2014 academic years using Web-based sports injury surveillance.

Design: 

Descriptive epidemiology study.

Setting: 

Online injury surveillance from soccer teams of high school boys (annual average = 100) and collegiate men (annual average = 41).

Patients or Other Participants: 

Boys' or men's soccer players who participated in practices and competitions during the 2005–2006 through 2013–2014 academic years in high school and the 2004–2005 through 2013–2014 academic years in college, respectively.

Main Outcome Measure(s): 

Athletic trainers collected time-loss (≥24 hours) injury and exposure data. Injury rates per 1000 athlete-exposures (AEs), injury rate ratios (IRRs) with 95% confidence intervals (CIs), and injury proportions by body site and diagnosis were calculated.

Results: 

High School Reporting Information Online documented 2912 time-loss injuries during 1 592 238 AEs; the National Collegiate Athletic Association Injury Surveillance Program documented 4765 time-loss injuries during 686 918 AEs. The injury rate was higher in college than in high school (6.94 versus 1.83/1000 AEs; IRR = 3.79; 95% CI = 3.62, 3.97). Injury rates increased with smaller school size for high schools and were higher in Division I than in Divisions II and III. The injury rate was higher during competitions than during practices in both high school (IRR = 3.55; 95% CI = 3.30, 3.83) and college (IRR = 3.45; 95% CI = 3.26, 3.65). Most injuries were to the lower extremity. However, concussion was a common injury, particularly in collegiate goalkeepers and at all positions for high school players. Concussions accounted for more than one-fifth of injuries in high school games.

Conclusions: 

Injury-prevention interventions should be tailored to reflect variations in the incidence and type of injury by level of competition, event type, and position.
Die God van die hemel
Authors: Oberholzer J.P.
Published: October 2018

No abstract available.
Die verhouding Heilige Gees en geloof by Paulus
Authors: Pelser G.M.M.
Published: October 2018

No abstract available.
Waar begin en waar eindig die amp
Authors: Pont A.D.
Published: October 2018

No abstract available.
Die Godsbegrip in die filosofie van Spinoza
Authors: Gericke J.D.
Published: October 2018

No abstract available.
Die ewige terugkeer van die wysgerig-antropologiese vraagstelling
Authors: Oberholzer C.K.
Published: October 2018

No abstract available.