bluuebunny/crossref_metadata_2025 huggingface dataset:
An Autopsy Based Retrospective Study on Pattern of Thoraco-Abdominal Injuries in Fatal Road Traffic Accidents of Kolar, South India
Authors: Rajkumar M G  , Srinivasa Reddy P  , Ajay Kumar T S  , Abhinandana R
Published: May 2023

Background: India is experiencing increasing road traffic accidents (RTA) amidst increasing motorization andinfrastructure growth in recent years. Every day, nearly 400 road deaths occur on Indian roads and severalthousands are hospitalized due to road crashes. WHO estimates the incidence of road deaths to be 16.6 per 100000population in India1. With the aim of studying pattern and exploring various epidemiological characteristics ofRTAs, this retrospective study of medico-legal autopsies was conducted.Aims & Objectives: 1 To study the pattern of thoraco-abdominal injuries (TAI) in fatal road traffic accidents inKolar. 2. To describe demographic profile and create public awareness on road safety.Material & Methods: A retrospective autopsy based study of pattern of thoraco-abdominal injuries in victims offatal road traffic accidents was conducted in Sri Devaraj Urs Medical College, Kolar (South India) from 1st January2014 to 31st December 2014. A total of 192 RTA victims were referred for autopsy during the period of which100 cases sustaining thoraco-abdominal injuries were studied.Results: A total of 192 medicolegal autopsies were conducted on victims of road traffic accidents (RTA) during thestudy period. Among them, 100 victims suffered thoraco-abdominal injuries, which accounted for 52.08% of thecases. The highest number of victims belonged to the age group of 20-40 years, accounting for 48% of the cases.In terms of gender distribution, males constituted 62.0% of the victims while females constituted 38.0%. The mostcommon injuries were to the liver, accounting for 37.75% of the total injuries. Other frequently affected body partsincluded the spleen, lungs, thorax, abdomen, pelvis, and spine.Conclusion: The analyzed data provides clear evidence that road accidents are foreseeable and avoidable. Tomake substantial improvements in road safety throughout India, it is essential to establish a robust and effectivenational and state-level road safety authority, foster intersectoral coordination, and secure regular funding. Ouraim in sharing this article is to increase public awareness of the significance of road traffic injuries from a publichealth perspective and to alleviate the weight of fatalities and injuries on our communities.
Nucleophile-induced ring contraction in pyrrolo[2,1-c][1,4]benzothiazines: access to pyrrolo[2,1-b][1,3]benzothiazoles
Authors: Lystsova Ekaterina A , Dmitriev Maksim V , Maslivets Andrey N , Khramtsova Ekaterina E
Published: May 2023

Pyrrolo[2,1-b][1,3]benzothiazoles are an important class of fused sulfur and nitrogen-containing heterocycles intensively studied in medicinal chemistry and pharmacology. In the present paper, a new synthetic approach to pyrrolobenzothiazoles is developed based on 1,4-thiazine ring contraction in 3-aroylpyrrolo[2,1-c][1,4]benzothiazine-1,2,4-triones under the action of nucleophiles. The proposed approach works well with alkanols, benzylamine, and arylamines. The scope and limitations of the developed approach are studied. The synthesized pyrrolobenzothiazole derivatives represent an interest to pharmaceutics, since their close analogs show CENP-E inhibitory activity, interesting for the targeted cancer therapy development.
Examination of Reference Value Preferences in Theses Prepared on the Existence of Values
Authors: DEMİRYÜREK Gökçe
Published: May 2023

The aim of this study is to determine the reference value preferences as an analysis unit in the graduate theses prepared on values education in our country. For this purpose, as a result of the search conducted with the concepts of "values" and "values education" in the YÖK thesis database, research was carried out on 340 theses prepared to determine the existence of values. The data of the study were coded through the form developed by the researcher and the data were analyzed by the content analysis method. As a result of the research, it was seen that the number of theses in question increased with small fluctuations since 2007 and reached the highest number in 2019. It has been determined that almost all of the theses prepared on this subject are master's thesis. Atatürk University, Gazi University and Necmettin Erbakan University are the prominent institutions in this field. More than half of these theses have been prepared in Turkish Language Education departments. In the most frequently used reference values, it was determined that the core values and the values in the Social Studies Course Curriculum were preferred. It was determined that almost half of the theses did not specify reference values. In the research conducted until 2019, it was seen that there was a tendency to take the values in the Social Studies Course Curriculum as reference values in all departments. In the theses prepared in 2019 and after, it was determined that there was a shift towards core values.
HYMENOPLASTY SURGERY SOCIO-LEGAL ASPECT: A REVIEW
Authors: Punam Shashi , Kumar Sanjeev
Published: May 2023

This article is a reflection of the rising complexity of the contemporary world, which is characterised by a rich variety of culture, morality, the legal system, and religion, all of which are capable of having a significant impact on medical practise. It is possible to rupture a hymen via sexual activity as well as through a number of other activities. In societies that place a high value on a woman retaining her virginity after marriage, a woman and her family may be stigmatised for having done so. Women, particularly brides whose virginity is not established at the time of marriage, face the risk of humiliation, ostracism, divorce, and violence; in the most severe cases, women risk being killed in the name of "honour." However, doctors may be opposed to hymen reconstruction on the grounds that it is dishonest, not necessary for medical reasons, discriminates against women, and promotes subjecting women to greater standards of virtue than are demanded of men. Many doctors explain that the operation by stating that it serves the patient's health, which may include the patient's emotional and social well-being as well as women's human rights to have control over their own bodies. In addition, many young people lose their virginity unintentionally as a result of rape or compulsion, and if women do not have their hymens reconstructed, they are at risk of physical assault and even death. In the surgery does not violate any laws but in the most cases women suffer from some risk and it should be confused with female genital cutting or mutilation.
O ENSINO DE GEOGRAFIA E INCLUSÃO DE CRIANÇAS AUTISTAS:
UM ESTUDO NA ESCOLA PAROQUIAL LUIZ AUGUSTO EM ARAGUAÍNA (TO)
Authors: Lima José Edmar Rocha , Venâncio Marcelo
Published: May 2023

São grandes os desafios encontrados no que se refere à educação inclusiva, principalmente na rede pública de ensino. Uma das principais questões discutidas pelos gestores e professores são as faltas de políticas públicas eficazes que dê suporte as escolas, para que ocorra a inclusão integral de pessoas com deficiência. Outro fato também importante é a adequação de acessibilidades nas estruturas das escolas que favoreça maior mobilidade da criança com deficiência. De modo que professores regentes e auxiliares capacitados possam perceber as dificuldades e necessidades dos alunos com autismo. São muitas as adversidades encontradas por professores da rede pública de ensino: uma delas é que parte significativa dos professores não foram preparados para lidar com alunos com algum tipo de deficiência.Abordaremos também um pouco da luta pelo direito à inclusão das pessoas com deficiência na rede pública de ensino, falaremos um pouco do contexto histórico e as leis que garantem o acesso à educação de deficientes na rede pública de ensino, será abordado também sobre o autismo e seus graus e limitações e o que pode ser feito para o desenvolvimento deste aluno com autismo.[...]
OLHAR SOBRE A EDUCAÇÃO DE JOVENS E ADULTOS (EJA) E A IMPORTÂNCIA DO PROFESSOR NESSA MODALIDADE EDUCACIONAL
Authors: Alves Carla Regina Carvalho , Reinaldo Thayssllorranny Batista
Published: May 2023

A Educação de Jovens e Adultos (EJA) é uma modalidade educacional garantida pela Lei de Diretrizes e Bases da Educação Brasileira (LDB) e atende jovens e adultos que não cursaram suas respectivas séries da Educação Básica na idade esperada. São estudantes que na sua maioria já são pai ou mãe de família, trabalhadores que exercem uma dupla ou até mesmo tripla jornada no seu dia a dia. Situação que acaba por contribuir direta ou indiretamente até mesmo para a evasão escolar. Trata-se de um contexto emblemático que merece um olhar atento por parte de geógrafos e demais pesquisadores das ciências humanas, situação que despertou na pesquisadora inquietações e interesse em pesquisar essa temática. [...]
Geographical variation in antimicrobial use and multiresistant pathogens in Brazilian intensive care units: a nationwide study
Authors: Ramos Oliveira Silva Alice , Xavier Borges Barbosa Constanza , Soares Rebelo Raianne , Fernandez-Llimos Fernando , Costa Lima Elisangela
Published: May 2023

Introduction: Geographical analyses of antibiotic use identify regions with the highest consumption and help design policies for strategic patient groups.
Methodology: We conducted a cross-sectional study based on official data available in July 2022 from Brazilian Health Surveillance Agency (Anvisa). Antibiotics are reported as a defined daily dose (DDD) per 1,000 patient-days, and central line-associated bloodstream infection (CLABSI) is defined according to Anvisa criteria. We also considered multi-drug resistant (MDR) as the critical pathogens the World Health Organization listed. We measured antimicrobial use and CLABSI trends per ICU bed using the compound annual growth rate (CAGR). Results: we evaluated the regional variation in CLABSI by multidrug-resistant pathogens and the antimicrobial use in 1,836 hospital intensive care units (ICUs). In 2020, the leader in use in intensive care units (ICUs) in the North was piperacillin/tazobactam (DDD = 929.7) in the Northeast. Midwest and South were meropenem (DDD = 809.4 and DDD = 688.1, respectively), and Southeast was ceftriaxone (DDD = 751.1). The North has reduced polymyxin use (91.1%), and ciprofloxacin increased (439%) in the South. There was an increase in CLABSI by carbapenem-resistant Pseudomonas aeruginosa in the North region (CAGR = 120.5%). Otherwise, CLABSI by vancomycin-resistant Enterococcus faecium (VRE) increased in all regions except the North (CAGR = -62.2%), while that carbapenem-resistant Acinetobacter baumannii increased in the Midwest (CAGR = 27.3%).
Conclusions: we found heterogeneity in antimicrobial use patterns and CLABSI etiology among Brazilian ICUs. Although Gram-negative bacilli were the primary responsible agent, we observed a notable increase trend of CLABSI by VRE.
A review of the assassin-fly genus Anypodetus Hermann, 1907 with the description of a new species (Insecta, Diptera, Asilidae)
Authors: Dikow Torsten , Dubus Meliah
Published: May 2023

The genus Anypodetus Hermann, 1907 (Diptera, Asilidae, Laphriinae) is reviewed. Currently, eight species are recognized from Botswana, Mozambique, Namibia, South Africa, Zimbabwe, and southern-most Zambia, i.e., Anypodetus arachnoides Oldroyd, 1974 widespread, Anypodetus fasciatus Hermann, 1907 widespread, Anypodetus fascipennis Engel, 1924 widespread, Anypodetus leucothrix Londt, 2000 restricted to southern Namibia and south-western South Africa, Anypodetus macroceros Londt, 2000 restricted to west-central Namibia, Anypodetus nigrifacies Ricardo, 1925 restricted to eastern-most South Africa and southern Mozambique, Anypodetus phalaros Londt, 2000 Namibia and South Africa, and Anypodetus unicolor Oldroyd, 1974 Namibia, eastern South Africa, adjacent Mozambique, and southern Zimbabwe. One new species, Anypodetus londtisp. nov. from Mozambique and Zimbabwe, is described for a total of nine species in the genus. Study of the secondary type specimens of A. unicolor from Namibia revealed that these specimens do not represent this species, reducing the number of species recorded from Namibia to six. Anypodetus leucothrix is recorded with several additional collecting events in central and northern Namibia extending its range significantly. Distribution, biology, occurrence in biodiversity hotspots sensu Conservation International, and seasonal imago flight activity are discussed. Diagnoses, photographs, specimen occurrence data, and an identification key to species are provided with the new species described in detail. The sexual dimorphism in the development of the mystax and wing vein variation in regard to the alignment of M2 and M3 are discussed and illustrated.
Older Adult Caregivers' Perspectives on Wound Care Resources: A Qualitative Study
Authors: Swartzell Kristen L. , Fulton Janet S. , von Gaudecker Jane R.
Published: May 2023

With an aging population, increasing numbers of older adults are assuming a caregiving role, including performing complex care procedures, such as wound care. Access to and use of resources are associated with better physical and mental health for caregivers. A thematic analysis of qualitative interviews with adult caregivers aged ≥65 years performing wound care identified seven resources supportive of the caregiver role, including: (a) access to expert guidance from health care professionals; (b) written instructions; (c) relationships with health care professionals for obtaining wound care supplies; (d) need for additional medical equipment; (e) financial resources; (f) coverage for caregiver personal time; and (g) select persons for caregiver social and emotional support. Given that older adults are increasingly cast into caregiver roles in the home setting, providing resources to sustain care recipients and their caregivers is critical. [
Research in Gerontological Nursing, 16
(4), 194–201.]
Multi-objective particle swarm optimization with reverse multi-leaders
Authors: Chen Fei , Liu Yanmin , Yang Jie , Yang Meilan , Zhang Qian , Liu Jun
Published: May 2023

Despite being easy to implement and having fast convergence speed, balancing the convergence and diversity of multi-objective particle swarm optimization (MOPSO) needs to be further improved. A multi-objective particle swarm optimization with reverse multi-leaders (RMMOPSO) is proposed as a solution to the aforementioned issue. First, the convergence strategy of global ranking and the diversity strategy of mean angular distance are proposed, which are used to update the convergence archive and the diversity archive, respectively, to improve the convergence and diversity of solutions in the archives. Second, a reverse selection method is proposed to select two global leaders for the particles in the population. This is conducive to selecting appropriate learning samples for each particle and leading the particles to quickly fly to the true Pareto front. Third, an information fusion strategy is proposed to update the personal best, to improve convergence of the algorithm. At the same time, in order to achieve a better balance between convergence and diversity, a new particle velocity updating method is proposed. With this, two global leaders cooperate to guide the flight of particles in the population, which is conducive to promoting the exchange of social information. Finally, RMMOPSO is simulated with several state-of-the-art MOPSOs and multi-objective evolutionary algorithms (MOEAs) on 22 benchmark problems. The experimental results show that RMMOPSO has better comprehensive performance.
Software reliability model for open-source software that considers the number of finite faults and dependent faults
Authors: Song Kwang Yoon , Kim Youn Su , Chang In Hong
Published: May 2023

Software has become a vital factor in the fourth industrial revolution. Owing to the increase in demand for software products in various fields (big data, artificial intelligence, the Internet of Things, etc.), the software industry has expanded more than ever before. Therefore, software reliability has become very important, and efforts are being made to increase it. One of these efforts is the development of software reliability models (SRMs). SRMs have been studied for a long time as a model that predicts software reliability by using the number of software faults. Software failures can occur for several reasons, including independent software faults such as code errors and software hangs, as well as dependent cases where code errors lead to other software faults. Recently, due to the diversity of software operating environments, software faults are more likely to occur in a dependent manner, and, for this reason, they are likely to increase rapidly from the beginning and progress slowly to the maximum number thereafter. In addition, many large companies have focused on open-source software (OSS) development, and OSS is being developed by many users. In this study, we propose a new SRM that considers the number of finite faults and dependent faults, and examine the goodness-of-fit of a new SRM and other existing non-homogeneous Poisson process models based on the OSS datasets. Through numerical examples, the proposed model demonstrated a significantly better goodness-of-fit when compared to other existing models, and it also exhibited better results on the newly proposed integrated criteria.
A knowledge and data-driven optimal planning scheme for multi-modal vision transmission systems
Authors: Yong Jia , Liu Kai
Published: May 2023

Vision transmission systems (VTS) manages to achieve the optimal information propagation effect given reasonable strategies. How to automatically generate the optimal planning strategies for VTS under specific conditions is always facing challenges. Currently, related research studies have dealt with this problem with assistance of single-modal vision features. However, there are also some other information from different modalities that can make contributions to this issue. Thus, in the paper, we propose a data-driven optimal planning scheme for multimodal VTS. For one thing, the vision features are employed as the basic mechanism foundation for mathematical modeling. For another, the data from other modalities, such as numerical and semantic information, are also introduced to improve robustness for the modeling process. On such basis, optimal planning strategies can be generated, so that proper communication effect can be obtained. Finally, some simulation experiments are conducted on real-world VTS scenes in simulative platforms, and the observed simulation results can well prove efficiency and proactivity of the proposal.
Searching for Job Security and the Consequences of Job Loss
Authors: Jarosch Gregor
Published: May 2023

Job loss comes with large present value earnings losses which elude workhorse models of unemployment and labor market policy. I propose a parsimonious model of a frictional labor market in which jobs differ in terms of unemployment risk and workers search off‐ and on‐the‐job. This gives rise to a job ladder with slippery bottom rungs where unemployment spells beget unemployment spells. I allow for human capital to respond to time spent out of work and estimate the framework on German Social Security data. The model captures the joint response of wages, employment, and unemployment risk to job loss which I measure empirically. The key driver of the “unemployment scar” is the loss in job security and its interaction with the evolution of human capital and, in particular, the search for better employment.
Political strategies and artistic representations: Mary of Hungary and the construction of the post-mortem image of Louis II Jagellon
Authors: García Pérez Noelia
Published: May 2023

This study analyzes how Mary of Hungary created and promoted the post-mortem image of Louis II to benefit the imperial policy of the Habsburg dynasty. To do so, reasons that led the queen of Hungary to draw up a series of representation strategies to vindicate her position as a pious widow, proclaim her legal rights over the territories of Hungary and Bohemia, and strengthen her relationship with the Hungarian monarchy will be examined. These artistic initiatives allowed her to maintain an active role in the European diplomatic scene, helping her reinforce her legitimacy as Governor of the Netherlands and to consolidate the authority of Ferdinand I against János Szapolyai.
El impacto de la producción científica y su relación con el desempeño ambiental
Authors: Altonar Gómez Ximena Aurora , Contreras Gómez Leobardo Eduardo , Gil Antón Manuel , Pérez Angón Miguel Ángel
Published: May 2023

Este trabajo tiene por objetivo estudiar la relación entre la producción de los documentos indexados del área de ciencias ambientales en la base de datos de SCOPUS y los países mejor evaluados dentro del Índice de Desempeño Ambiental (EPI). Para realizarlo, se analizan de forma bibliométrica los tres primeros lugares del EPI de los años 2014, 2016 y 2018, y tres países latinoamericanos, Brasil, Costa Rica y México. Entre los análisis desarrollados se encuentran: una categorización temática utilizando las palabras clave de la producción de ciencias ambientales valiéndose de los ejes del EPI como variable de identificación, comparación estadística respecto a la producción científica de cada país y el tipo de acceso de la misma. Se encontró que los países con una gobernanza fuerte (países mejor evaluados dentro del índice) no guardan relación con una mayor producción de publicaciones de ciencias ambientales.
A Computational Protocol for the Study and Design of Effective Organic Corrosion Inhibitors
Authors: El-Hendawy Morad
Published: May 2023

While traditional corrosion scientists design new corrosion inhibitors through structural modification and testing hundreds of compounds in the lab with practical means that are costly in terms of time and materials, successive and continuous developments in hardware and software make the design process faster and cheaper. This chapter introduces a computational protocol to differentiate the performance of organic corrosion inhibitors. On the other hand, it can be used to design new anticorrosive inhibitors. Another aim of this chapter is to correct common mistakes in conducting computational calculations. The protocol includes three successive phases of calculations: I- DFT-examination of the reactivity of the isolated molecules before the adsorption process. II- Studying the physical adsorption of molecules on the metallic surface using Monte Carlo (MC) or molecular dynamics (MD) simulations. III- Studying the chemical adsorption of molecules on the metallic surface using density functional-based tight binding (DFTB) or periodic density functional theory (DFT) methods.
Effect of Capping Agent on the Shape and Catalytic Activity of PtPd Bimetallic Alloy Nanostructures
Authors: Johan Ooi Mahayatun Dayana , Yusaini Nurshahzleen Mohd , Mahmood Ainorkhilah , Napiah Noorezal Atfyinna Mohammed , Yusof Yushamdan
Published: May 2023

In this work, PtPd nanostructures have been synthesized via the chemical reduction method with different capping agents (i.e., PVA, PVP, and PEG), whilst the strong reducing agent, NaBH4, was used in this study to reduce the metal salt to zero-valent PtPd nanostructures. Both PtPd synthesized with PVP and PEG exhibit nanoparticle structures, whereas PtPd synthesized in PVA demonstrates large, interconnected network structures. Pt-Pd synthesized with PVP exhibits a high ECSA value of 692.68 m2/g compared to without capping agent (287.80 m2/g) indicating large active sites, which increases its catalytic function. This study concludes that the presence of a capping agent influences the morphological structure and the catalyst's efficiency in performing a redox reaction at the surface.
Evidence for Aerosol Transfer of SARS-CoV-2–Specific Humoral Immunity
Authors: Kedl Ross M , Hsieh Elena W Y , Morrison Thomas E , Samayoa-Reyes Gabriela , Flaherty Siobhan , Jackson Conner L , Rochford Rosemary
Published: May 2023

Infectious particles can be shared through aerosols and droplets formed as the result of normal respiration. Whether Abs within the nasal/oral fluids can similarly be shared between hosts has not been investigated. The circumstances of the SARS-CoV-2 pandemic facilitated a unique opportunity to fully examine this provocative idea. The data we show from human nasal swabs provides evidence for the aerosol transfer of Abs between immune and nonimmune hosts.
Quality of recovery in hospital and disability-free survival at three months after major abdominal surgery
Authors: Kinugasa Yuki , Ida Mitsuru , Nakatani Shohei , Uyama Kayo , Kawaguchi Masahiko
Published: May 2023

Background: The Quality of Recovery-15 (QoR-15) and 12-item World Health Organization Disability Assessment Schedule 2.0 scales are post-surgery patient-reported outcome measures. We aimed to evaluate the association between immediate in-hospital postoperative recovery and mid-term disability-free survival (DFS) after discharge.Methods: We conducted a prospective observational study at a university hospital and enrolled 260 patients aged ≥ 65 years with cancer who were undergoing elective major abdominal surgery. The association between poor postoperative recovery, defined as a QoR-15 score < 90 on postoperative day (POD) 2, and the DFS three months later was assessed using Fisher’s exact test. The odds ratio of poor recovery on POD 2 to DFS was calculated using multiple logistic regression analysis adjusted for prominent factors (age, preoperative frailty, preoperative DFS, surgical duration, and intraoperative blood loss volume).Results: A total of 230 patients completed the 3-month follow-up. On POD 2, 27.3% of the patients (63/230) had poor recovery. A greater number of patients without poor recovery on POD 2 had DFS at three months after surgery (79.6%) than those with poor recovery (65.1%) (P = 0.026). The adjusted odds ratio of poor recovery on POD 2 to DFS at three months was 0.481 (95% CI [0.233, 0.994]).Conclusions: Patients with poor recovery on POD 2 were less likely to have DFS three months after abdominal surgery. These findings may allow for early and effective interventions to be initiated based on each patient’s condition after abdominal surgery.
The identification of misplaced moral ingredients that obscure sustainable leadership
Authors: Slater Jennifer
Published: May 2023

This article endeavours to liberate the concept of ‘morality’ and debrief the term ‘sustainability’ by exploring the fundamental moral questions that relate to leadership based on ethical living connected with self, others, nature and the environment. It investigates sustainability that cultivates leadership and undergirds the social, economic, political and moral subsistence of humanity. It explores the dire deficiencies of moral ingredients that have infiltrated all kinds of leadership that consequently restrain social transformation. The decay of unethical leadership that resulted in the unsustainability of regular life requires investigation because both morality and sustainability need liberation, to be ‘unfrozen’ from their ‘static’ or inoperative states so as to become once again positively functional in the practice of leadership. While ethics and morality focus on building correct relationships that uphold honourable living, it is also defined by an affiliation with a divine component that nourishes our collective well-being on earth. Entrenched moral assumptions that make it impossible to move morality forward are challenged so as to discharge our principled obligations to humans and the planet alike. The overarching aim is to formulate an ethical theory that defines a set of moral qualities that are exclusively aimed at sustaining the intrinsic worth of all, promoted by both individual and corporate leadership, that embraces reasonableness, independence, integrity, productiveness and justice.Intradisciplinary and/or interdisciplinary implications: The article is housed in the discipline of Christian Leadership with theological ethics, moral theology and gospel values that interrogate the emasculation of sustainable leadership.
Expanding the Geographic Boundaries of Melioidosis in Queensland, Australia
Authors: Gassiep Ian , Grey Victoria , Thean Li Jun , Farquhar Drew , Clark Julia E. , Ariotti Lawrence , Graham Rikki , Jennison Amy V. , Bergh Haakon , Anuradha Satyamurthy , Dyer Wendy , James Christian , Huang Andrea , Putt Elise , Pakeerathan Veenaa , Griffin Paul M. , Harris Patrick N. A.
Published: May 2023

Melioidosis is an infectious disease caused by the bacterium Burkholderia pseudomallei. Although this environmental organism is endemic in certain regions of Australia, it is not considered endemic in Southern Queensland, where the last case was reported 21 years ago. We report a climate change–associated outbreak of melioidosis occurring during two La Niña events in a region previously considered nonendemic for B. pseudomallei. During a 15-month period, 14 cases of locally acquired melioidosis were identified. Twelve patients were adults (> 50 years), with diabetes mellitus the most common risk factor in 6 of 12 patients (50%). Eleven patients (79%) had direct exposure to floodwaters or the flooded environment. This study suggests an association between climate change and an increased incidence of melioidosis. In addition, this is the first report of environmental sampling and whole-genome analysis to prove endemicity and local acquisition in this region.
Evidence of Distinct Genetic Stocks of the Bottlenose Wedgefish (Rhynchobatus australiae) in the Indo-West Pacific
Authors: Simwanza Rehema J. , Rumisha Cyrus
Published: May 2023

Populations of the bottlenose wedgefish (Rhynchobatus australiae) in the Indo-West Pacific (IWP) have declined by nearly 80% in recent decades. In response, IWP countries are establishing sanctuaries to provide refuge for the fish. However, little is known about the genetic stock structure of the fish in the region. Hence, this study analysed partial sequences (610 base pairs) of the cytochrome oxidase subunit (COI) gene from eight bottlenose wedgefish populations in the IWP to assess the genetic stock structure of the fishery. The sequences revealed that Western Indian Ocean (WIO) populations are genetically distinct from those in the West Pacific (WP) (FCT = 0.24, p = 0.01) and Australia (FCT = 0.88, p = 0.01). Similarly, WP populations were genetically distinct from Australian populations (FCT = 0.42, p = 0.01). This suggests that the IWP contains three genetically distinct stocks of the bottlenose wedgefish: the WIO, WP, and Australia. The indices of genetic diversity and population size showed that the WIO stock has low genetic diversity and population size when compared to the WP and Australia. This shows that efforts to establish elasmobranch sanctuaries in the IWP should take into account the three identified stocks, with priority given to the WIO.

Keywords:    Restricted gene flow, genetic connectivity, elasmobranch sanctuaries, Indo-West Pacific Ocean
Software disruption as unfair competition: China’s experience in the legal regulation of technical behaviors
Authors: Feng Shujie
Published: May 2023

The rapid growth of the software- and internet-related economy has conferred upon China particular experience in settling unfair competition disputes regarding software disruption. New technical means of competition have enabled intrusion into or disruption of another’s business operations concerning software or online products and services. By adopting case law and special rules on internet-related unfair practices, Chinese courts and legislators have had a generally negative view of software intrusion or disruption, which should be reevaluated in light of the freedom of competition. New technical means are not obstacles in the way of application of the rules on classic unfair practices such as confusion, misrepresentation and defamation. However, the internet and software have increased aggressive commercial practices and the physical disruption of business operations, which makes it necessary to adopt rules on these two types of unfair practices.
Archiwalia dotyczące wielkopolskich gmin żydowskich w zbiorach Gesamtarchiv der deutschen Juden (przed 1939 r.)
Authors: Witkowski Rafał
Published: May 2023

Rozwój instytucji naukowych w Niemczech w drugiej połowie XIX w. oraz początku XX w. zaowocował powstaniem profesjonalnego archiwum gromadzącego rozproszone do tej pory źródła, związane z historią Żydów na ziemiach niemieckich. Gesamtarchiv der deutschen Juden rozpoczął oficjalnie swoją działalność 1 października 1905 r. i wkrótce stał się najważniejszym Archiwalia dotyczące wielkopolskich gmin żydowskich w zbiorach Gesamtarchiv... 169 i największym archiwum żydowskim w Niemczech. Burzliwe losy zbiorów w okresie reżimu faszystowskiego oraz konsekwencje II wojny światowej spowodowały, że pierwotna kolekcja została rozproszona, a wiele materiałów archiwalnych bezpowrotnie zniszczono. Artykuł prezentuje fragmenty zachowanych spisów archiwaliów o Żydach w Wielkopolsce, jakie były przygotowywane w momencie przekazywania ich do Gesamtarchiv der deutschen Juden.

Archival documents regarding Jewish communities in Greater Poland in the pre-1939 collection of Gesamtarchiv der deutschen Juden

The evolution of scientific institutions in Germany in the second half of the 19th century and the early 20th century brought about the establishment of a professional archive gathering previously dispersed resources on the history of Jews in the German territories. Gesamtarchiv der deutschen Juden was officially launched on October 1, 1905, and soon became the largest and the most important Jewish archive in Germany. The turbulent history of the collection during the times of the fascist regime and in the years following the Second World War caused the original collection to be scattered, while many archival materials were completely destroyed. The article presents parts of the preserved lists of archival documents regarding Jews in Greater Poland that were prepared at the moment of their incorporation into the Gesamtarchiv der deutschen Juden.
Wokół tajemniczego dokumentu Jana z Cardony (Archiwum Państwowe w Poznaniu)
Authors: Lange Tadeusz W.
Published: May 2023

Artykuł stanowi rozwiązanie zagadki wtórnie użytej połówki XV-wiecznego pergaminowego dokumentu znajdującego się w posiadaniu Archiwum Państwowego w Poznaniu. Pierwotny dokument zostaje tu zidentyfikowany jako list odpustny wystawiony przez baliwa Jana z C ardony na mocy pełnomocnictwa Sykstusa IV w trakcie papieskiej kampanii mającej na celu zebranie funduszy na obronę wyspy Rodos i zbrojną akcję przeciwko Turkom. W artykule opisana jest sama kampania i rola w niej Katalończyka Joana z C ardony. Podane są także przykłady wyemitowanych wówczas listów odpustnych, na bazie których dokonana zostaje rekonstrukcja tekstu brakującej połowy listu.

Around the mysterious document of Juan de Cardona (State Archive in Poznań)

This article solves the mystery of the missing half of a 15th century parchment document, owned by the State Archive in Poznań. The original document is identified here as a letter of indulgence issued by bailiff Juan de Cardona pursuant to the power of attorney of the pope Sixtus IV during the papal campaign aiming at collecting funds to protect Rhodes and launch an armed action against the Turks. The article describes the campaign and the role of Catalan Juan de Cardona in the campaign. It also provides examples of letters of indulgence issued back then, which were used as a template to reconstruct the missing half of the letter.
Pursuit of individual ambidexterity by middle managers and their psychological well-being.
Authors:   , Moccia Andrea
Published: May 2023

Companies increasingly demand ambidexterity from their employees, the ability to flexibly switch between exploitation (use and refine existing competencies) and exploration (explore new opportunities and create new knowledge) (Holmqvist & Spicer, 2012). From a job design perspective, ambidexterity is seen as a valuable form of job enrichment that can increase employee creativity, innovation and motivation (T. J. M. Mom et al., 2018; Parker, 2014). However, studies have also indicated that the demand for ambidexterity may lead to frustration, anger and stress among employees (Karhu, 2017; T. Keller & Weibler, 2015; Laureiro-Martínez, Brusoni, & Zollo, 2010). Despite these warnings, the possible negative impact on employee well-being has received little attention in the literature (Agnihotri et al., 2017; Caniëls & Veld, 2016; Tempelaar & Rosenkranz, 2017). This thesis addresses this research gap. Taking into account the moderating effect of the Big Five personality traits as well as the team climate, the influence of the demand for ambidexterity on on middle managers' well-being is investigated. The impact of the demand for ambidexterity on well-being was investigated using the data from an anonymous online survey of administrative middle managers from different divisions and professions of Swiss Post. The analysis of data from the 1,657 participants suggests that the demand for ambidexterity does not generally pose a particular threat to middle managers' well-being. However, the results also suggest that the demand for ambidexterity does not have a positive impact on psychological well-being. It was also found that personality, in contrast to team climate, has a significant moderating effect. Concretely, it was found that extraversion positively influences the impact of the demand for ambidexterity on middle managers' well-being, while the personality traits conscientiousness and neuroticism have a negative influence. This research provides a significant contribution by closing a long-known research gap. The findings on the role of personality traits further contribute to the advancement of the individual ambidexterity theory. The research provides equally valuable insights for practice. Employers have been in the dark about the effect of the demand for ambidexterity among their middle managers. The findings from this research inform employers that by introducing ambidextrous jobs, they are not generally putting their middle managers at significant risk, nor are they promoting their well-being. Furthermore, the finding of this research that the two personality traits conscientiousness and neuroticism tend to have a negative impact on psychological well-being when ambidexterity is demanded, and extraversion does the opposite is of great importance for employers. Since psychological assessments based on the five-factor model of personality are a common tool in the recruitment process, employers are now able to systematically select middle managers for ambidextrous jobs.
Developing a feasible model for delivering quality hospital-based experiential learning for pharmacy undergraduate students funded by the healthcare education and training tariff
Authors: Hindley Ben , Wright Sally , Peasley Mark
Published: May 2023

The Department of Health and Social Care (UK) provides funding to support clinical placements for healthcare students in England through their education and training tariff, which is administered by Health Education England (HEE). From September 2022, undergraduate pharmacy students became eligible for this funding to support their experiential learning. Development of quality, feasible experiential learning for pharmacy students within the context of the tariff proved challenging for both higher education institutions (HEIs) and hospital placement providers. Barriers to delivery were identified and addressed, such as no HEE published strategy for placement delivery, as well as the financial constraints of the tariff payments which made placements unattractive to providers. Pharmacy school inexperience of arranging longer placements and a substantial administrative burden added to the challenge. This report outlines the developmental process behind the experiential learning that is now delivered by Liverpool John Moores University and the local hospital providers.
Analysis of parents’ awareness on the chronic kidney disease in children
Authors: Trofimova Arina G. , Fisenko Andrey P. , Arzumanov Sergey V.
Published: May 2023

Introduction. Informing the population about chronic kidney disease is an important factor for preventing or combating the disease, and maintaining the health of the younger generation.
Objective: to study the level of awareness of parents about chronic kidney disease.
Methods. In a specially designed form, an anonymous survey of 112 parents of children treated at the department regarding chronic kidney disease was conducted. Statistical processing of the obtained results was carried out.
Results. In most children (91.6%), the diagnosis of chronic kidney disease was established at the stage C3–C5 in the hospital. Moreover, in 100% of cases, this diagnosis was a “random finding”; 75.9% of respondents showed lack of information about the disease and its treatment, and the level of awareness is directly related to the stage of the disease. Moreover, as a result of insufficient information, the parents admitted to fail to comply with the terms of visiting the child, a nephrologist (22.9%), the recommendations to limit the diet of protein (19.3%) and potassium (36.2%), fluid volume (61.5%). At the same time, the parents believed the cause of the progression of chronic kidney disease in the child to be the lack of follow-up (43.7%), late diagnosis (33.7%), improper treatment (13.3%), and the late beginning of the treatment (9.6%).
Conclusion. The work proved a low degree of awareness about chronic kidney disease, which contributes to the late diagnosis of the disease and low adherence to treatment. This problem requires improving methods and forms of informing the population, including expanding the capacity of outpatient care (preventive examinations, health education in nephrology schools).
Bone mineral density in schoolchildren and students of the city of Krasnodar
Authors: Sutovskaya Diana V. , Burlutskaya Alla V. , Gorbacheva Liubov V. , Karachevtseva Dariya Y.
Published: May 2023

Introduction. The state of bone tissue mineralization reflects the quality of the overall development in children and adolescents, their functional status, and the level of general health. The formation of a genetically determined peak bone mass begins at birth and continues until the age of 25 years, providing skeletal strength throughout life.
Materials and methods. There were examined five hundred seventy five people including 427 11–18 years schoolchildren and 148 19–25 years students. Bone mineral density (BMD) was assessed by 2-energy X-ray absorptiometry in the distal forearm bones using a DTX-200 densitometer (USA). A decrease in BMD was recorded at Z score < –2.0 SD for a given age and gender. A questionnaire was used to assess risk factors for a decrease in BMD.
Results. A decrease in BMD among schoolchildren was registered in 9.9% of respondents. The prevalence of BMD deficiency in girls was 13.3%, in boys — 5.4%. The results of densitometry among students showed a decrease in bone mineralization in 12.1%. A comparative analysis of the decrease in BMD in the age aspect among schoolchildren and students did not reveal significant differences. In all schoolchildren with insufficient BMD, there were noted following risk factors as a pronounced deficiency in dietary calcium intake, physical inactivity, sugar abuse, vitamin D deficiency in 76.1%, deficiency in 23.9%, a history of fractures — 25.5%, smoking — 31.1%. In all students with a decrease in BMD also there were found 4 or more risk factors including low intake of dietary calcium, physical inactivity, low levels of vitamin D (deficiency -64.2%, deficiency — 35.8%), more than 5 cups of coffee per day — 35.1%, smoking — 46.6%, history of fractures — 33%.
Conclusion. The goal of educational work among parents, schoolchildren and students should be the formation of correct food preferences, which in the future will be the base for the prevention of a decrease in BMD.
A rare case of the combination of total abnormal pulmonary vein drainage with congenital lung lymphangiectasia
Authors: Sarsenbayeva Gulzhan I. , Sadykova Altynay Zh. , Berdibekov Almas B. , Khasanova Olesya Z.
Published: May 2023

The article describes a clinical report of a combination of congenital heart disease due to total anomalous pulmonary venous drainage into the right atrium with congenital lung disease — lymphoangiectasia in a newborn infant. The role of extracardiac pathology on the course and outcome of cardiac surgery and the complexity of early diagnosis of a rare lung pathology are presented
Polymorphisms of genes of the renin-angiotensin system: significance in the progression of chronic kidney disease in children
Authors: Sedashkina Olga A. , Poretskova Galina Yu. , Makovetskaya Galina A.
Published: May 2023

Introduction. A comprehensive analysis of the polymorphisms of the genes of the renin-angiotensin system in children with different nosological forms of nephropathies is a necessary step in determining the clinical and genetic features of the formation of chronic kidney disease (CKD).
Aim: to establish the features of ACE (D/I), GT (Thr174Met), AGT (Met235Thr) and AGTR1 (A1166C) gene polymorphisms in CKD children and determine their significance in the progression of the disease.
Materials and methods. A retrospective and prospective study included one hundered 1 to 17 years children with nephropathies, examined in the children’s nephrology department of the Samara Regional Hospital over 10 years. In children, the identification of single nucleotide polymorphisms of genes was carried out using an allele-specific polymerase chain amplification reaction using test systems. Evaluation of clinical and paraclinical markers of progression in CKD was carried out twice a year. The results of the study were evaluated with the calculation of the Student–Fisher criteria and correlation analysis.
Results. in patients with kidney diseases, there was a trend towards an increase in the occurrence of single nucleotide polymorphisms of genes that affect the renin-angiotensin system (RAS). CKD patients at the stage 3–5 accounted for 35%. They had D/D ACE alleles combined with alleles AGT Thr174Met (27.9 ± 6.83%) and Met235Thr (41.86 ± 7.5%), Thr235Thr (30.2 ± 7.0%) and AGTR1 A1166C (37.2 ± 7.32%) more often than in milder CKD (0 and 7.5 ± 3.37%; 5.2 ± 2.94% and 5.2 ± 2.94%; respectively, p ≤ 0.010).
Соnclusion. The study of clinical and genetic features of CKD is relevant for the purpose of timely implementation of preventive measures.
AN EXPLORATION INTO THE WOODEN FURNITURE INDUSTRY THROUGH THE THEORETICAL LENS OF PORTER’S CLUSTER- A CASE STUDY OF KHAIRPUR MIRS
Authors: Khaskhely Mahvish , Naqvi Iffat , Isran Manzoor
Published: May 2023

Furniture industry of Pakistan is considered as one of the high potential yet neglected clusters. This industry is famous for its elaborate wooden carvings on the blocks of Sheeshum and Rosemary. The leading furniture making areas of Pakistan are Chiniot, Gujrat, Peshawar, Lahore and Karachi. However, Pakistan’s share in the international wooden furniture market is insignificant, despite the fact that the country has a history of craftsmanship and innovation in the field of wooden furniture. Especially Sindh region which specializes in wood furniture making have not been explored for its potential in increasing the furniture export. Further, there is a dearth of literature pertaining to their geographical clustering as well as the causes of the underdevelopment of interior Sindh’s wooden furniture industry. In response to this gap, this case study research a) conducts geographical mapping of Khairpur Mirs wooden furniture industry through GIS, and b) constructs a SWOT Matrix in light of Porter’s Cluster Theory on the basis of thematic analysis. The findings highlight that the location of the business units is at Station Road from Khaki Shah pull to Nimm More (approximately 1 km area) with around 150 to 200 furniture houses/ manufacturers. This research identifies the causes of underdevelopment of wooden furniture cluster in Khairpur on the basis of which participant driven solutions are proposed. Finally, this research presents policy recommendations to improve this small scale industry’s potential for socio economic growth.