bluuebunny/crossref_metadata_2025 huggingface dataset:
Pandemic changes in work, rest, physical activity and diet versus nutritional status of respondents
Authors: Jawień Wiktoria , Kania Barys Barbara , Kądziołka Anna , Jurkiewicz Beata
Published: November 2022

The aim of the study was to determine how the COVID-19 pandemic affected the nutritional status of the respondents through changes in work mode, physical activity and diet among residents of the Tarnów region.

Material and methods. The study was conducted using the diagnostic survey method, and the tool was the author's questionnaire. The study was conducted in January-February 2022, using the Google Forms platform. In total, data were collected from 414 people. The questionnaires were filled out mostly by women (67.9% vs. 32.1%). The average age of respondents was 31.9 years (±13.52).

Results. Those who worked remotely and in hybrid mode had the highest percentages declaring an increase in food intake during the COVID-19 pandemic (65.0% and 59.7%, respectively). The highest percentages of those who indicated a deterioration in the quality of their food intake were those who worked remotely (60.0%) and hybrid job (45.5%), while those who did not work were the group that most often among the others indicated an improvement in the quality of their food (23.4%). Respondents with remote and hybrid jobs were the most likely to report a reduction in their activity level (72.5% and 58.4%, respectively). Considering the BMI of those surveyed before the COVID-19 pandemic and now, there is an apparent decrease in the percentage of those with a normal BMI in favor of overweight and obesity.

Conclusions. During the COVID-19 pandemic period, the percentages of overweight and obese people increased. People working remotely and in hybrid mode not only increased the amount of food they consumed, but also began to consume lower-quality products, as well as more often reporting reduced levels of physical activity.
Clinical significancy of WNT pathway inhibition in various cancers
Authors: Rogaczewski Patryk , Janiak Michał , Borysewicz Kamil , Głos Tadeusz , Ahmadi Navid , Szylberg Łukasz
Published: November 2022

The tumor microenvironment (TME) plays an important role in the cell cycle. There is a correlation between the Wnt/B–catenin signaling pathway and TME. This article reviews methods of inhibiting Wnt Pathway, a useful process in the treatment of various cancers. Compounds of Wnt/β–Catenin Signaling Pathway, such as TCF–1, have an impact on the differentiation and migration of CD8+ T cells. CCL4 expression is regulated by the beta–catenin protein to recruit CD103+ dendritic cells, which enables CD8+ T cell activation. Inhibition of the Wnt/β–catenin pathway has an impact on ovarian cancer patients’ prognosis, reducing the development of ovarian cancer. Research shows that inhibition of the pathway with the use of the LGK974 inhibitor may boost immunity, especially when applied with a Paclitaxel mix. After treatment, expression of the inhibitory receptors CTLA–4, TIM3, PD–1 on CD8+ T cells decreased. The combination of LGK974 and Paclitaxel can cause the death of tumor cells and significantly inhibit their proliferation. The application of dose–dense Paclitaxel avoids toxicity related to the maximum dose needed to protect the patient's immune system by increasing CD8+ TILs.  There are concerns regarding toxicity of the LGK 974, especially for cells dependent on the Wnt/β–catenin pathway to maintain homeostasis. Many Wnt/β–catenin pathway inhibitors are tested against colorectal cancer (CRC) with successful results. These include NSAIDs, porcupine inhibitors, tankyrase inhibitors, Wnt5A inhibitors, and disheveled protein inhibitors.The Wnt/β–catenin pathway, when expressed in Triple Negative Breast Cancer (TNBC), leads to the transition of epithelial to mesenchymal cells. In early clinical development, there are multiple inhibitors (ex. KYA1797K) targeting the Wnt/β–catenin pathway in TNBC cells, which could become a viable anticancer strategy.
Processo de trabalho do profissional de Educação Física na atenção básica em territórios do campo
Authors: Lima Fernando de , Almeida Maria Deisyelle Sibaldina da Silva , Melo Taynara Poliana Gonçalves de , Rodrigues Junior Wellington da Silva , Da Silva Nicole Caroline Nascimento , Silva Ranieri Moreira da , Francisco Larissa Manuelle Marciano , Santos Danyela Lays dos , Lages Itamar , Lemos Emmanuelly Correia de
Published: November 2022

O objetivo do estudo foi descrever o processo de trabalho do profissional de Educação Física na Atenção Primária à Saúde em territórios do campo. Estudo do tipo relato de experiência sistematizado a partir das vivências dos profissionais residentes de Educação Física, inseridos na Atenção Primária à Saúde nos territórios do campo dos municípios de Garanhuns e Caruaru, cidades do Agreste Pernambucano, com populações quilombolas e assentados de territórios de reforma agrária, no período de janeiro a agosto de 2021. O processo de trabalho dos profissionais de Educação Física no campo é marcado por agentes, objetos, meios, produtos e resultados que caracterizam o trabalho na Atenção Primária, composto por ações de núcleo e outras abrangentes, além das especificidades da área. Perpassa por atividades individuais, coletivas,  a partir da realidade e necessidades específicas da população do campo,contribuindo com a atenção à saúde, facilitando a coordenação e continuidade do cuidado dessa população.
Impact of Own Brand Product Introduction on Optimal Pricing Models for Platform and Incumbent Sellers
Authors: Cheng Hsing Kenneth , Jung Kyung Sung , Kwark Young , Pu Jingchuan
Published: November 2022

Sales on the e-commerce platform in the United States have experienced explosive growth and are projected to surpass $740 billion in 2023. The expansion of the platform’s traditional role as a reseller into an online marketplace and the introduction of its own brand products have stoked a huge fear among the incumbent sellers. The platform’s unfair anti-competitive practice further aggravates the situation. Consequently, politicians and regulators have proposed prohibiting platforms from introducing own brand products to protect the incumbent sellers. This study addresses two questions of critical interest to the policymakers and the incumbent sellers. First, how does the platform’s introducing its own brand product affect the incumbent sellers? Second, how effective is the proposed policy in terms of protecting the incumbent sellers? We examine the impact of the platform’s own brand introduction on the incumbent sellers under two prevailing sell-on and sell-to pricing contracts. We find that the proposed legislation “that prohibits platforms from both offering a marketplace for commerce and participating in that marketplace” does not have the desired outcome of helping the incumbent sellers. Instead, it forces the platform to adopt only the sell-to contract with its own brand introduction which hurts the sellers under most market conditions.
Providing Data Samples for Free
Authors: Drakopoulos Kimon , Makhdoumi Ali
Published: November 2022

We consider the problem of a seller of data who sells information to a buyer regarding an unknown (to both parties) state of the world. Traditionally, the literature explores one-round strategies for selling information because of the seller’s holdup problem: once a portion of the data set is released, the buyer’s estimate improves, and as a result, the value of the remaining data set drops. In this paper, we show that this intuition is true when the buyer’s objective is to improve the precision of the estimate. On the other hand, we establish that when the buyer’s objective is to improve downstream operational decisions (e.g., better pricing decisions in a market with unknown elasticity) and when the buyer’s initial estimate is misspecified, one-round strategies are outperformed by selling strategies that initially provide free samples. In particular, we provide conditions under which such free-sample strategies generate strictly higher revenues than static strategies and illustrate the benefit of providing data samples for free through a series of examples. Furthermore, we characterize the optimal dynamic pricing strategy within the class of strategies that provide samples over time (at a constant rate), charging a flow price until some time when the rest of the data set is released at a lump-sum amount.

This paper was accepted by Itai Ashlagi, revenue management and market analytics.

Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2022.4534 .
The transition of a mental health facility to a COVID-19 isolation ward and unit to deliver remote inpatient mental health care
Authors: Corrigan Mary , Curran Michelle , Kirwan Shane , Donohue Gráinne , Keogh Brian
Published: November 2022

Throughout the COVID-19 pandemic, mental health services were confronted with significant challenges and mental health staff have not only had to provide a continued service for, often distressed, service users but have had to adapt practice and comply with the ever-changing public guidelines for containing the virus. There is a pressing need, therefore, to learn from the challenges that mental health services have faced and continue to face throughout different stages of the pandemic. While uncertainty is inevitable in pandemics, mental health nurses as a community can learn from individual experiences of adaptation.

This article describes the unique and rapid transition of one Irish mental health facility to a COVID-19 isolation ward and unit for delivery of remote admission to a mental health service (home care admission). In order to capture this transitory experience, the areas discussed include preparation of the site, key challenges and the role of nursing staff, mental health service delivery, managing home care packages, the nurse management role and remote ward nursing. This discussion demonstrates how one mental health setting successfully evolved and met the challenges brought by the global pandemic through a combination of adaptability and flexibility in service delivery.
Approaches to mental health care in 19th and early 20th century England
Authors: Nolan Peter
Published: November 2022

In the mid-19th century, it was generally held by administrators and politicians that institutional confinement was the answer to many social problems. However, there were those both within and outside psychiatry who were concerned about what they perceived to be the limitations of the asylum system given that mental illness was poorly categorised – for example, it was uncertain whether alcohol abuse was an illness – the treatments unproven, and there were likely to be adverse effects of long-term institutionalisation. The size of institutions was questioned, as was the role of the private sector and whether the mentally ill could be entrusted to the care of poorly regulated facilities. This paper examines some of the expressed concerns about care of the mentally ill throughout the second half of the 19th century by reformers and psychiatrists with reference to the culture and management of institutions and private facilities, the exploitation of vulnerable people, and the emergence of home-based care provided by experienced and skilled nurses.
Design and Evaluation of a Control System for the Fertigation Device
Authors: Zhang Zhiyang , Chen Chao , Li Hong , Xia Huameng
Published: November 2022

Highlights

A control system based on single-chip microcomputer and fuzzy control was designed for solid fertilizer applicators.

The working parameters can be adjusted and detected accurately.

The fertilization performance of the fertigation device improved after accessing the control system.

Under the adjustment of the control system, the fertigation device can achieve variable fertilizer concentrations.

Abstract. In view of low automation control and unstable output fertilizer solution concentrations of solid fertilizer applicators, a control system based on a single-chip microcomputer and fuzzy control was proposed and introduced into a fertigation device. The control system calculated and adjusted the fertilizer-feeding flow rate according to the input and feedback information, resulting in the automatic operation of the fertigation device. It can also detect the output fertilizer concentration in real time. Experiments were conducted to test the adjustment and detection accuracy of the control system and to investigate its performance. Adjustment and detection errors were below 5% when the inlet water flow rate, the fertilizer-feeding flow rate, and the fertilizer concentration were 0.2 to 1.5 m3/h, 1 to 50 kg/h, and 1 to 14 g/L, respectively. The time the output fertilizer reached the set concentration was around 5 minutes and was far shorter than the fertigation device without a control system. The fertilizer concentration deviation decreased by about 20% after accessing the control system for the fertigation device. Under the control system, the fertigation device can discharge fertilizer with a variable concentration, and the fertilization deviation was about 5%. Therefore, the control system not only made automatic operation and variable concentration fertilization of the fertigation device to be achieved but also improved the fertilization performance of the fertigation device. Keywords: Fertigation device, Fertilization concentration deviation, Fuzzy control, Single-chip microcomputer, Variable fertilizer concentration.
Influence of Tempering Methods on Waxy White Sorghum Kernel, Milling, and Flour Properties
Authors: Yoganandan Mohana , Buenavista Rania Marie , Bean Scott R. , Aramouni Fadi M. , Dogan Hulya , Siliveru Kaliramesh
Published: November 2022

Highlights

Tempering moisture content and condition had a significant impact on waxy white sorghum kernel and flour properties.

Physical sorghum kernel properties after tempering varies with efficiency of moisture penetration into kernels.

Steam tempering for 15 s led to better physical kernel properties for handling, transportation, and processing.

Room temperature water tempering (18%, 24 h) yielded better flour yield and protein content.

Abstract. To optimize the yield and quality of waxy white sorghum flour, the effects of various tempering treatments on sorghum kernel physical properties, milling performance, and flour properties were evaluated. Waxy white sorghum kernels were tempered at different moisture levels and for different times using either room temperature water, hot water, or steam. Tempered sorghum kernels were milled into flour using a milling flowsheet developed for a laboratory-scale tabletop roller mill that consists of four break rolls and eight reduction rolls. The effects of these tempering methods on waxy white sorghum kernel properties, roller milling, and flour properties were investigated. Tempering moisture content and condition had a significant impact on the waxy white sorghum kernel’s physical and flour properties. Steam tempering for 15s led to desirable physical kernel properties that would positively impact handling, transportation, and processing: lower bulk (732.53 kg/m3), tapped (769.39 kg/m3), and true densities (1313.37 kg/m3); lower hardness index (65.01); higher abrasive hardness index (AHI) (23.73); higher angle of repose (23.60); and higher coefficients of static (0.35) and rolling friction (0.29). In terms of milling, room temperature water tempering at 18% w.b. moisture level for 24 h resulted in better bran-endosperm separation without compensating for important flour quality characteristics. It exhibited higher protein content (9.72%), low ash content (0.94%), high bran extraction (6.42%), and high brightness (80.67). Room temperature water tempering at 18% w.b. for 24 h is a more suitable pretreatment prior to the milling of waxy white sorghum kernels in terms of flour yield and quality. Keywords: Flour properties, Kernel properties, Roller milling, Tempering, Waxy white sorghum.
Pseudoaneurysm of the Lateral Genicular Artery Following Unicompartmental knee Arthroplasty: A Rare Case Report
Authors: Rajani Amyn M , Rajani Kareena , Shah Urvil A , Mittal Anmol RS , Sheth Rahul , Punamiya Meenakshi
Published: November 2022

Introduction: Unicondylar knee replacement is a minimally invasive technique of surface replacement of the knee joint. Very little literature is available regarding vascular complications in patients who undergo this procedure due to their extremely rare nature. Case Report: This first-of-its-kind report describes a case of pseudoaneurysm of the lateral genicular artery of the right knee in a hypertensive, 65-year-old man, following a single sitting bilateral unicompartmental knee replacement (UKR). With no involvement of the lateral compartment in UKR, we suspect an underlying mechanical element as the cause of the pseudoaneurysm. Patient presented with swelling and pain in the right knee for the first time at 8-month postoperatively, and after aspiration of the hemarthrosis, had two events of recurrence with increasing frequency. Dynamic magnetic resonance angiography confirmed the diagnosis and the patient underwent angiography-guided embolization of the lateral genicular artery using polyvinyl alcohol particles, with no recurrence in over a year since then. Conclusion: Pseudoaneurysm of the lateral genicular artery is a possible cause of recurrent hemarthrosis even after unicondylar knee replacement and requires a high degree of suspicion for its timely diagnosis and management.
Per què introduir la perspectiva interseccional al debat teòric sobre ciutadania intercultural?
Authors: Lladonosa Mariona , Öztürk Okumuş Özgür Güneş
Published: November 2022

En el context de les anomenades conflictivitats (post)nacionals apareix el repte de configurar un model de ciutadania que incorpori l'eix del reconeixement en interacció amb la igualtat. El model intercultural és el marc en què s'està donat aquesta reflexió actualment. L'article proposa una introducció a les tesis que sustenten la idea de la ciutadania intercultural dins del paradigma republicanista. En segon lloc, planteja una anàlisi crítica de dos dels elements que proposa el model intercultural: el contacte interpersonal i l’espai públic. En tercer lloc, s'exposen diverses demandes de reconeixement dels col·lectius minoritzats en origen a Catalunya. I en darrer lloc, es mostra la distància entre els arguments que sostenen la teoria intercultural i les demandes exposades. L'article revisa el debat de ciutadania introduint la perspectiva de les dominacions i les formes de despossessió estructurals de la societat, i proposa la reconceptualització de les polítiques de reconeixement com a estratègia per a la igualtat real i la justícia global.
Restoring Women’s Dignity Through Fistula Repairs: Exploring the Challenges and Coping Strategies of Zimbabwean Women
Authors: Shumba Lilivale , Mutambara Julia , Hungwe Chipo
Published: November 2022

Objective. This study identifies and analyses the impact of fistula repair towards the restoration of women’s dignity and their coping strategies or methods of adjustment to society. The study is critical given the negative effects of fistula on the identities of women and their loved ones. Materials And Methods. The study employed a qualitative case study which used purposive sampling to select participants for in-depth interviews with seven women (age range 17 to 42). Data were grouped into themes and analysed. Thematic analysis identified the main themes as; negative experience, stigma and positive coping strategies facilitating proper adjustment. Discussion And Conclusions. Social stigma continues even after surgery and is the major challenge that participants have to deal with daily affecting the level of integration into the community. It also threatened the extent to which fistula survivors can be perceived and perceive themselves as ‘dignified’. Participants faced mental health challenges like anger, sadness, depression, anxiety, stress and shame. However, participants acknowledged that through family support, empowerment programmes and community support, they were slowly getting back to their normal lives.
Proceso de validación de manual para supervisores de prácticas clínicas de estudiantes de obstetricia como material de apoyo pedagógico
Authors: Méndez Hax Isabeau
Published: November 2022

Objetivo. Diseñar un manual de apoyo al matrón/a docente clínico asistencial que ejerza en hospitales públicos en Chile que pueda fortalecer el proceso de enseñanza/aprendizaje en el estudiante que cursa su cuarto año de la carrera de Obstetricia, durante su periodo de práctica clínica en unidades de preparto/parto. Material y Método. Investigación Cualitativa. Este proyecto fue validado por cuatro expertos en el área de docencia universitaria de la carrera de Obstetricia, de profesión matrón/a. Realizando la validación a través de un formato oficial brindado por la Universidad Andrés Bello, donde se realiza este proyecto de investigación de Tesis, y donde se analizan preguntas tanto de formato, consistencia y conceptos, como también preguntas de contenido, aporte e impacto. Debido a situación sanitaria, este proyecto no pudo ser aplicado en campos clínicos. Resultados. Los resultados fueron divididos en tres aspectos: forma, contenidos y general, donde se puede graficar el nivel de aprobación de cada pregunta y ámbito de este manual, y la factibilidad completa de este. Conclusiones. A través de esta investigación se puede concluir lo importante que puede ser incorporar materiales de apoyo a los docentes asistenciales matrón/a, y que la incorporación de un manual es un método factible que puede mejorar la experiencia entre docente y estudiante.
Opto-thermal dynamics of thin-film optical limiters based on the VO2 phase transition
Authors: Tognazzi Andrea , Gandolfi Marco , Li Bohan , Ambrosio Gina , Franceschini Paolo , Camacho-Morales Rocio , Cino Alfonso Carmelo , Baratto Camilla , de Ceglia Domenico , Neshev Dragomir , De Angelis Costantino
Published: November 2022

Protection of human eyes or sensitive detectors from high-intensity laser radiation is an important challenge in modern light technologies. Metasurfaces have proved to be valuable tools for such light control, but the actual possibility of merging multiple materials in the nanofabrication process hinders their application. Here we propose and numerically investigate the opto-thermal properties of plane multilayered structures with phase-change materials for optical limiters. Our structure relies on thin-film VO2 phase change material on top of a gold film and a sapphire substrate. We show how such a multi-layer structure can act as a self-activating device that exploits light-to-heat conversion to induce a phase change in the VO2 layer. We implement a numerical model to describe the temporal evolution of the temperature and transmittivity across the device under both a continuous wave and pulsed illumination. Our results open new opportunities for multi-layer self-activating optical limiters and may be extended to devices based on other phase change materials or different spectral regions..
Establishing the proportion of severe/moderately severe vs mild cases of progressive disseminated histoplasmosis in patients with HIV
Authors: Nacher Mathieu , Adenis Antoine , Blaizot Romain , Abboud Philippe , Le Turnier Paul , Françoise Ugo , Lucarelli Aude , Demar Magalie , Djossou Félix , Epelboin Loïc , Couppié Pierre
Published: November 2022

Background

Progressive disseminated histoplasmosis remains a major but neglected cause of death among patients with advanced HIV. Recently, aiming to reduce avoidable deaths, the Pan American Health Organization issued the first diagnosis and treatment guidelines for HIV-associated histoplasmosis. But what proportion of progressive disseminated histoplasmosis in HIV-infected patients is severe is currently not known. Because this proportion influences treatment needs, we aimed to estimate this in a cohort of 416 patients in French Guiana.

Methods

We used the definition in the recent PAHO/WHO guidelines for severity. We used regression modelling to predict the impact of CD4 count on the proportion of severe cases. In a territory where treatment cost is not a limiting factor and where histoplasmosis is well known, we assumed that clinicians’ initial treatment reflected their perception about the severity of the case and therefore, the needs for different treatments.

Results

Using these definitions, since the beginning, there were 274 (65.9%) severe/moderately severe cases and 142 (34.1%) mild cases. In practice 186 cases were treated with deoxycholate or liposomal amphotericin B (44.7%) and 230 (55.3%) cases treated with itraconazole as first line treatment. The Kappa concordance measure between the guideline definition and the actual treatment given was 0.22. There was a 9% risk difference for death within 30 days of antifungal treatment initiation between severe/moderately severe and mild cases. Over threequarters (77%) of early deaths were attributed to severe/moderately severe cases.

Conclusions

This is the only rigorous estimate of the proportion of severe/moderately severe cases of progressive disseminated histoplasmosis in symptomatic HIV patients on the largest published cohort. These numbers may help defend budget needs for rapid diagnostic tests and liposomal amphotericin B.
Haematological predictors of poor outcome among COVID-19 patients admitted to an intensive care unit of a tertiary hospital in South Africa
Authors: Chapanduka Zivanai C. , Abdullah Ibtisam , Allwood Brian , Koegelenberg Coenraad F. , Irusen Elvis , Lalla Usha , Zemlin Annalise E. , Masha Tandi E. , Erasmus Rajiv T. , Jalavu Thumeka P. , Ngah Veranyuy D. , Yalew Anteneh , Sigwadhi Lovemore N. , Baines Nicola , Tamuzi Jacques L. , McAllister Marli , Barasa Anne K. , Magutu Valerie K. , Njeru Caroline , Amayo Angela , Wanjiru Mureithi Marianne W. , Mungania Mary , Sono-Setati Musa , Zumla Alimuddin , Nyasulu Peter S.
Published: November 2022

Background

Studies from Asia, Europe and the USA indicate that widely available haematological parameters could be used to determine the clinical severity of Coronavirus disease 2019 (COVID-19) and predict management outcome. There is limited data from Africa on their usefulness in patients admitted to Intensive Care Units (ICUs). We performed an evaluation of baseline haematological parameters as prognostic biomarkers in ICU COVID-19 patients.

Methods

Demographic, clinical and laboratory data were collected prospectively on patients with confirmed COVID-19, admitted to the adult ICU in a tertiary hospital in Cape Town, South Africa, between March 2020 and February 2021. Robust Poisson regression methods and receiver operating characteristic (ROC) curves were used to explore the association of haematological parameters with COVID-19 severity and mortality.

Results

A total of 490 patients (median age 54.1 years) were included, of whom 237 (48%) were female. The median duration of ICU stay was 6 days and 309/490 (63%) patients died. Raised neutrophil count and neutrophil/lymphocyte ratio (NLR) were associated with worse outcome. Independent risk factors associated with mortality were age (ARR 1.01, 95%CI 1.0–1.02; p = 0.002); female sex (ARR 1.23, 95%CI 1.05–1.42; p = 0.008) and D-dimer levels (ARR 1.01, 95%CI 1.002–1.03; p = 0.016).

Conclusions

Our study showed that raised neutrophil count, NLR and D-dimer at the time of ICU admission were associated with higher mortality. Contrary to what has previously been reported, our study revealed females admitted to the ICU had a higher risk of mortality.
The prevalence of psychiatric comorbidities in adult ADHD compared with non-ADHD populations: A systematic literature review
Authors: Choi Won-Seok , Woo Young Sup , Wang Sheng-Min , Lim Hyun Kook , Bahk Won-Myong
Published: November 2022

Comorbid psychiatric disorders in adults with ADHD are important because these comorbidities might complicate the diagnosis of ADHD and also worsen the prognosis. However, the prevalence of comorbid psychiatric disorders in adult ADHD varies according to the diagnostic tools used and the characteristics of target populations. The purpose of this review was to describe the prevalence of comorbid psychiatric disorders in adults with ADHD compared with adults without ADHD. Thirty-two studies published before August 2022 were identified and classified according to diagnosis of other psychiatric disorder in those with ADHD. The most frequent comorbid psychiatric disorder in the ADHD group was substance use disorder (SUD), followed by mood disorders, anxiety disorders, and personality disorders. The prevalence of these four disorders was higher in the ADHD group, whether or not subjects were diagnosed with other psychiatric disorders. In addition, the diversity of ADHD diagnostic tools was observed. This also might have affected the variability in prevalence of comorbidities. Standardization of ADHD diagnostic tools is necessary in the future.
Efficacy and safety of tibial cortex transverse transport for diabetic foot: A protocol for systematic review and meta-analysis
Authors: Guo Jiaxing , Bao Huhe , Lideer  , Ni Xiyu , Zhao Yaxin , Sun Guanwen
Published: November 2022

Introduction

Diabetic foot (DF) is one of the most serious chronic complications of diabetes. In recent years, the use of the tibial cortex transverse transport (TTT) technique has enabled great progress in microcirculation reconstruction and achievement of good outcomes in DF treatment. The objective of this systematic review protocol is to evaluate the efficacy and safety of TTT for DF.

Methods

Literature search was conducted using the Cochrane Library, Embase, PubMed, Web of Science, China Science Technology Journal Database (VIP), Wanfang Data, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Service System (SinoMed), and Chinese Biomedical Literature Service System (CBM) from inception until March, 1st 2022. In addition, our reviewers will retrieve dissertations, grey literature, systematic reviews, and reference lists of the relevant studies. Randomized controlled trials (RCTs) which compared the TTT for DF with conventional treatment will be included. Our reviewers will perform subgroup analysis, sensitivity analysis, and publication bias analysis to evaluate the heterogeneity and robustness. RevMan 5.3 software and Stata V.16.0 software will be used to analyze the available data.

Ethics and dissemination

Ethical approval was not required because this protocol neither collected private information, nor involved animal experiments. The research was disseminated by academic journals or related meetings.

PROSPERO registration number

CRD42021279717.
The application of resilience assessment grid in healthcare: A scoping review
Authors: Safi Mariam , Thude Bettina Ravnborg , Brandt Frans , Clay-Williams Robyn
Published: November 2022

Background

The Resilience Assessment Grid (RAG) has attracted increasing interest in recent healthcare discourse as an instrument to understand and measure the resilience performance of socio-technical systems. Despite its growing popularity in healthcare, its applicability and utility remain unclear. This scoping review aims to understand the practical application of RAG method and its outcomes in healthcare.

Method

We followed the Arksey and O’Malley, and the Levac and colleagues’ framework for scoping reviews and the PRISMA-ScR Checklist. We conducted searches of three electronic databases [Medline, Embase and Web of Science] in May 2021. Supplementary searches included Google Scholar, web and citation searches, and hand searches of the nine seminal edited books on Resilience Engineering and Resilient Health Care. All English language, empirical studies of RAG application in the healthcare setting were included. Open Science Framework [Registration-DOI. 10.17605/OSF.IO/GTCZ3].

Results

Twelve studies met the inclusion criteria. Diversities were found across study designs and methodologies. Qualitative designs and literature reviews were most frequently used to develop the RAG and applied it in practice. Eight of the studies had qualitative designs, three studies had mixed-methods designs and one study had a quantitative design. All studies reported that the RAG was very helpful for understanding how frontline healthcare professionals manage the complexity of everyday work. While the studies gained insights from applying the RAG to analyze organizational resilience and identify areas for improvement, it was unclear how suggestions were implemented and how they contributed to quality improvement.

Conclusion

The RAG is a promising tool to manage some of the current and future challenges of the healthcare system. To realise the potential benefits of the RAG, it is important that we move beyond the development phase of the RAG tool and use it to guide implementation and management of quality initiatives.
MATING BEHAVIOR AND BREEDING OF THE BLUE TREE MONITOR, VARANUS MACRAEI IN AN IN-COUNTRY FACILITY IN INDONESIA: A PRELIMINARY NOTE
Authors: Rahmanto Beny , Arida Evy , Fithria Abdi , Soendjoto Mochammad Arief
Published: November 2022

The Blue tree monitor, Varanus macraei Böhme & Jacobs, 2001 is a tree monitor species favored by reptile keepers. Successful captive breeding was reported from hobbyists and zoos in Europe shortly after its scientific description. Meanwhile, commercial farming to supply international demands has been progressing in Indonesia. However, such successful ex-situ breeding efforts have not yet been documented or published in Indonesia thus far. Therefore, in this, study we describe for the first time the mating behavior and reproduction of a V. macraei couple in an in-country outdoor facility, which is a common husbandry practice for monitor lizard breeders in Indonesia. The male started to approach the female at the beginning of the dry season, in May, with the female showing defensive behavior towards the male, both before mating and after laying eggs, pointing to a seasonal reproductive behavior. Monitor lizards were observed being active during the daytime. Eggs were laid by mid-July 2020. Two of the six eggs laid were revealed to be fertile and hatched after about 23 weeks (5.6 months). The two hatchlings were reared in an indoor enclosure, but only one survived, which showed to be a male.
A Content Analysis of Documentation of Nature Play in Early Childhood Teacher Education Program in Australia
Authors:   University of New England, Green Nicole , Christopher Vicki ,   University of Southern Queensland, Turner Michelle ,   University of Southern Queensland
Published: November 2022

This study theoretically aligns with research that purports that nature play positively contributes to sustainability stewardship. Early childhood teachers can plan for and nurture children’s capabilities and dispositions for sustainability stewardship. Initial teacher education programs contribute to the professional learning of preservice early childhood teachers’ perceptions regarding nature play. This article details the findings of content analysis to explore and uncover the existence of nature play in online, publicly available documents representing twenty-two early childhood teacher qualifications. In what ways is nature play evidenced in early childhood initial teacher education programs in Australia? The findings highlight potential discrepancies between the values related to nature play in the early childhood field and the content in initial teacher education programming. The article concludes with implications for teacher education programs and proposed recommendations for ongoing research.
Early Childhood Teachers’ Perceptions of Environmental Sustainability: A Phenomenographic Investigation
Authors:   University of Malta, Malta, Spiteri Jane
Published: November 2022

Early childhood teachers’ environmental perceptions can influence young children’s learning about environmental issues. Yet, to date, there is minimal research focusing on the perceptions of environmental sustainability held by early childhood teachers. This qualitative phenomenographic study collected data via individual semi-structured interviews with five early childhood teachers and one head teacher, in Malta. Preliminary findings revealed that the participants perceived environmental sustainability in terms of environmental concerns; environmental responsibility; and environmental protection. A mismatch between the participants’ environmental concerns and their pro-environmental behaviour emerged. The data also show that any environmental activities at school were done so uncritically. These findings hold importance for the reorientation of in-service and pre-service early childhood teacher education programs towards sustainability to ensure that systems thinking around critical environmental issues are introduced in the early years by addressing gaps in knowledge and supporting educators' development at the earliest stage (i.e., pre-service).
Self-Determination, Multinational Federalism and an Emerging Threat in Ethiopia: A Decolonial Approach
Authors: Regassa Asebe
Published: November 2022

With the coming to power of Abiy Ahmed in April 2018 following a popular movement that was initially sparked in Oromia and then spread to other regions, there was a short period of euphoria over the country's political landscape. Ethiopians and the international community alike were optimistic of democratic transition that would lead to the opening up of political and media spaces, fair and free elections, consolidation of the multinational federal system, the strengthening of autonomy of regional states, peace and stability, equitable resource distribution and equal socioeconomic opportunities for citizens. But, to the dismay of many observers, Abiy and his entourages shifted the narrative to the restoration of imperial system rather than strengthening the already existing multinational federal system. The return to imperial imaginations is both discursively and practically evident in Ethiopia's political discourses, in particular since 2018. Polarized political views between supporters and critics of multinational federalism have not only created a tense political environment but also partly contributed to the war in Tigray and Oromia. The country's three-decade long experiment with the federal system now faces a serious challenge of reversal. As the thesis and antithesis of multinational federalism have become salient forces shaping the country's political order, this article seeks to contribute to the existing debate, in particular contextualizing the discussion within decolonial literature. I argue that the current controversy over the nature of state structure is part of the struggle between forces promoting the right to self-determination and those favoring a unitary system.
State-Building and Development in Ethiopia: From “Developmental State” to “Prosperity” Model
Authors: Wayessa Gutu Olana
Published: November 2022

State-building and development are mutually reinforcing phenomena. The sustainability of development depends on the stability of state's political-structural foundation and the prospect of peace, which is influenced by the origin and evolution of the state. Every regime in Ethiopia has portrayed its advent as a new dawn for the country's development. In recent history, the Ethiopian People's Revolutionary Democratic Front (EPRDF) introduced a “developmental state” model and registered notable economic growth on aggregate but failed on accounts of equitable distribution. The EPRDF regime used the “developmental state” model to enhance the centralization of state power and circumvent regional autonomy. In 2018, the Prosperity Party (PP) introduced a “prosperity” model. From the EPRDF to the PP, there are signals of a radical shift of approach in state-building and development. This article analyzes the premises and promises of the multinational federation and “developmental state” model under the EPRDF regime, and the unitarist orientation and “prosperity” paradigm under the PP. I argue that the radical shift of direction from the multinational federalism towards a unitary state is unrealistic and fundamentally shatters the prospect of development.
National Integration through Political Marginalization: Contradictions of Nation-Building in Ethiopia
Authors: Gebissa Ezekiel
Published: November 2022

In Ethiopia, the nationalities question has been the most contentious political force shaping politics, engendering conflicts and obstructing national integration. In this article, I provide a historical analysis of the emergence in the 1960s of two dominant positions, “ethionationalism” and ethnonationalism, which coalesced into competing political visions of the character of the Ethiopian state. I posit that advocates of the two positions wrested power and tried to shape the state, writing constitutions and introducing political systems for governing Ethiopia. I discuss the transformation of these political positions and realignments as those in power maneuvered to deny Oromo nationalists access to political power, rejecting the idea of self-determination as a solution to the nationalities question. I conclude that the competing nationalisms have failed, and that the only way to create a stable Ethiopian state remains the position that Oromo nationalism has enunciated for half a century.
Mind the gap between non-activated (non-aggressive) and activated (aggressive) indoor fungal testing: impact of pre-sampling environmental settings on indoor air readings
Authors: Efthymiopoulos Spyros , Yasemin Aktas , Hector Altamirano
Published: November 2022

Indoor fungal testing has been within the researchers’ scope of interest for more than a century. Various sampling and analysis techniques have been developed over the years, but no testing protocol has been yet standardised and widely accepted by the research and practitioner communities. The enormous diversity in fungal taxa within buildings with varied biological properties, and implications on the health and wellbeing of the occupants and the building fabric complicates the decision-making process for selecting an appropriate testing protocol. This study aims to present a critical review of non-activated and activated approaches to indoor testing, with an emphasis on the preparation of the indoor environment prior to sampling. The study demonstrates the differences in the outcomes of non-activated and activated testing through a set of experimental work in idealised conditions and a case study. The findings suggest that larger particles are particularly sensitive to the sampling height and activation, and that non-activated protocols, despite dominating the current literature, can significantly underestimate the fungal biomass and species richness. Therefore, this paper calls for better-defined and activated protocols that can enhance robustness and reproducibility across the research domain focused on indoor fungal testing.
Principales factores impulsores de compromiso en developers según su etapa de carrera en la empresa de transformación digital Global Task
Authors: Taibo Martín , Troilo Fernando
Published: November 2022

El objetivo principal del estudio fue identificar los más importantes factores impulsores del compromiso en developers, según la etapa de su carrera (Jr., SSr., Sr.) en una empresa pequeña, con crecimiento exponencial y talento disperso en Latinoamérica: Global Task. En primer lugar, se realizó una investigación del marco teórico relevante sobre compromiso de los empleados, con el desarrollo de las principales teorías y definiciones sobre el compromiso organizacional y de los empleados y caminos posibles para la detección y medición de este en equipos tradicionales y equipos globales virtuales. Para cumplir con el propósito de la investigación se implementó un estudio de caso, en la empresa Global Task a través de la implementación de encuestas a todos sus developers. Finalmente se consiguió identificar los cinco principales factores de compromiso, siendo que la compensación económica y beneficios, junto con las oportunidades de desarrollo de carrera y aprendizaje resultaron ser en general los principales según la etapa de carrera de los developers. También se plantearon estrategias y un plan de acción para mejorar la gestión del compromiso en la empresa.
No sólo se aprendió Análisis Matemático
Authors: Mas María Magdalena , Cámara Viviana
Published: November 2022

Este trabajo presenta el desarrollo completo de una experiencia educativa realizada en la cátedra de Análisis Matemático de la Facultad de Ciencias Económicas de la Universidad Nacional del Litoral, en el segundo cuatrimestre del 2019. La misma tuvo por objetivo superar, por un lado, las dificultades que presentan los estudiantes en cuanto a determinados logros en el estudio de los contenidos disciplinares. Y por otro lado con la misma importancia, lograr que sean independientes en su aprendizaje. Por ello, su diseño tuvo en cuenta las ideas de Jacques Rancière (2014) en cuanto a la emancipación intelectual, al desarrollo de las competencias según Deulofeu (2009) y al Aprendizaje Cooperativo (Johnson, Johnson y Holubec 1999). El grupo de alumnos en que se aplicó la propuesta estuvo conformado fundamentalmente por recursantes. La experiencia resultó altamente positiva considerando que en términos cuantitativos el porcentaje de aprobados superó ampliamente el promedio de la asignatura y en términos cualitativos los estudiantes valoraron positivamente aspectos como el trabajo en equipo y la superación personal.
La recepción moderna del mejor de los mundos posibles
Authors: Cubells María Ramón
Published: November 2022

En este artículo se presenta la recepción que tuvo en la modernidad la teoría de Leibniz conocida como doctrina del optimismo. Aunque son las interpretaciones de Kant y de Hegel las que nos van a ocupar, para contextualizar la doctrina del mejor de los mundos posibles, será imprescindible referirnos a la acogida inmediata que la tesis tuvo en la Ilustración. A continuación, se analizará el texto de Kant «Algunas observaciones sobre el optimismo» y su defensa de las tesis de Leibniz. Dedicamos el último apartado del artículo a la lección que Hegel dedicó a la cuestión del optimismo de Leibniz en sus Lecciones sobre la historia de la filosofía.
Del idealismo trascendental al empirismo trascendental
Authors: Pachilla Pablo
Published: November 2022

En el presente texto, se pregunta por el pasaje del idealismo trascendental de Immanuel Kant al empirismo trascendental de Gilles Deleuze. Sostendremos dos hipótesis: en primer lugar, que el principal elemento distintivo del segundo con respecto al primero es la ausencia de una condición de concordancia entre los flujos de las diferentes facultades; en segundo lugar, que la escena que Deleuze construye para dar cuenta de una síntesis disyuntiva entre elementos heterogéneos está a su vez inspirada en Kant, más específicamente en la Analítica de lo sublime. Deleuze reelabora esta escena, en su primer sistema filosófico propio, para construir un encuentro que violenta la sensibilidad y fuerza a las diferentes facultades a un ejercicio autónomo que rompe con el sentido común y, sin embargo, encuentra una armonía en el fondo de la discordancia.