bluuebunny/crossref_metadata_2025 huggingface dataset:
TAVI for Pure Native Aortic Regurgitation: Are We There Yet?
Authors: Arias Eduardo A , Bhan Amit , Lim Zhan Y , Mullen Michael
Published: March 2019

Treatment of degenerative aortic stenosis has been transformed by transcatheter aortic valve implantation (TAVI) over the past 10–15 years. The success of various technologies has led operators to attempt to broaden the indications, and many patients with native valve aortic regurgitation have been treated ‘off label’ with similar techniques. However, the alterations in the structure of the valve complex in pure native aortic regurgitation are distinct to those in degenerative aortic stenosis, and there are unique challenges to be overcome by percutaneous valves. Nevertheless some promise has been shown with both non-dedicated and dedicated devices. In this article, the authors explore some of these challenges and review the current evidence base for TAVI for aortic regurgitation.
Contemporary Management of Stent Failure: Part One
Authors: Pal Nikhil , Din Jehangir , O’Kane Peter
Published: March 2019

The occurrence of in-stent restenosis (ISR) still remains a daunting challenge in the current era, despite advancements in coronary intervention technology. The authors explore the underlying pathophysiology and mechanisms behind ISR, and describe how the use of different diagnostic tools helps to best elucidate these. They propose a simplistic algorithm to manage ISR, including a focus on how treatment strategies should be selected and a description of the contemporary technologies available. This article aims to provide a comprehensive outline of ISR that can be translated into evidence-based routine clinical practice, with the aim of providing the best outcomes for patients.
Olga Cossettini y el Colegio Libre de Estudios Superiores en Rosario (Argentina), 1939-1940
Authors: Fernandez Sandra Rita
Published: March 2019

Este artículo explora la organización de la filial Rosario del Colegio Libre de Estudios Superiores (CLES), emblemática agrupación de fuerte impronta intelectual en el escenario argentino entre los años treinta, cuarenta y cincuenta del siglo XX. En particular, haremos énfasis en el contexto de inserción de la filial y en las tramas de sociabilidad que reunieron a un ecléctico grupo de colaboradores y simpatizantes, con plurales posiciones intelectuales, estéticas y políticas. En tal sentido, pretendemos detenernos especialmente en la figura de Olga Cossettini y su rol dentro de la gestación de la filial, de la que fue secretaria general entre los años 1951 y 1954.
Joanne Rappaport y Tom Cummins. Más allá de la ciudad letrada: letramientos indígenas en los Andes
Authors: Ceballos Bedoya Nicolás
Published: March 2019

Reseña de Joanne Rappaport y Tom Cummins. Más allá de la ciudad letrada: letramientos indígenas en los Andes. Bogotá: Universidad Nacional de Colombia, Universidad del Rosario, 2016, 368 pp.
Aguzar la mirada colectiva, el gran desafío de la historia ambiental latinoamericana
Authors: Leal Claudia
Published: March 2019

Este ensayo propone que el gran desafío de la historia ambiental latinoamericana es alterar el panorama de la historia de la región, haciéndolo más completo y preciso, no solo para los historiadores ambientales sino para todos. La inclusión del medio ambiente en la historia permite examinar desde nuevos puntos de vista viejos problemas históricos, así como proponer nuevos temas de investigación. El reto entonces no se centra tanto en identificar vacíos en el campo de la historia ambiental, sino en buscar estrategias para permear la lectura general del pasado regional. El texto revisa la trayectoria de la inclusión de temas ambientales en la historiografía colombiana e invita a los lectores a escribir monografías contundentes, hacer trabajos comparativos y buscar socios dentro y fuera de la academia para así construir una visión del pasado más compleja, nítida y colorida, y lograr una mejor comprensión de nuestra realidad actual.
En diálogo con un mundo antiguo: las pinturas de las casas coloniales de Tunja en el marco de un Renacimiento global
Authors: Zalamea Patricia
Published: March 2019

A través de un análisis comparativo —entre estrategias narrativas producidas en un mismo contexto; entre contextos distintos pero cuyos procesos de construcción cultural dependen de una reformulación de la visualidad en la modernidad temprana; y entre medios y dispositivos visuales que producen, pero también reorganizan el conocimiento— este artículo propone una nueva interpretación de las célebres pinturas murales de las casas tunjanas de finales del siglo XVI y la primera parte del siglo XVII, en el marco de un Renacimiento global. En este proceso, se reconsideran los conceptos que han sido utilizados en interpretaciones anteriores, tales como originalidad, identidad y exotismo, matizando así el enfoque tradicional de los estudios iconográficos que han predominado en la interpretación de estos murales. Dicha perspectiva permite salirse del paradigma binario en el que suelen inscribirse las interpretaciones del uso de las fuentes grabadas; así, se redimensiona el problema de las fuentes y de las relaciones habitualmente establecidas entre texto e imagen. Finalmente, se contextualizan dichas pinturas en su entorno específico, pero en un marco global, que a su vez redistribuye el modelo de centro y periferia.
Емоционалната интелигентност – условие за успешна професионална изява на педагогическите специалисти
Authors: Величкова Александрина
Published: March 2019

Проблемът за изследването на емоционалния интелект на педагога в контекста на професионално значимите качества на личността остава и до този момент недостатъчно изучен в най-новата българска научна действителност. Нарастването на интереса към въпросите, свързани с емоционалната компетентност и професионалното самоосъзнаване на педагозите във връзка с успешността на дейността им е обусловено от съвременните социални тенденции и основни цели на образование. Чрез развитието на емоционалната интелигентност като значим фактор за повишаване на психологическата култура, педагогическите специалисти ще усъвършенстват своята емоционална компетентност, ще повишат нивото на професионалното си майсторство, ще обогатят възможностите си за пълноценна личностна и професионална изява и реализация.
Формиране на умения за кариерно ориентиране у учениците от 1 клас чрез извънкласните дейности
Authors: Петровa Татяна
Published: March 2019

В ОУ „Неофит Рилски“ гр. Габрово от 2017/18 учебна година бе сформиран клуб„Млад предприемач“ по Проект „Твоят час“, на който съм ръководител. Целта ми е разработване и апробиране на модел за формиране на кариерно ориентиране на учениците от I клас чрез извънкласните дейности. Някои занятия проведохме в училище, а други извън традиционната учебна среда - в музей, фирма, магазин, пожарна. Разработих портфолио с проведените занятия и Програма, които се съхраняват в училищната библиотека и са част от методологията за обмяна на добри практики на педагозите от училището. Резултатите на учениците бяха представени в Деня на таланта с инициативата „Какъв да стана?“.
Когато училището създава активна иновативна учебна среда, с внимание, насочено към всяко отделно дете и неговата личност, то възпитава знаещи и мислещи млади хора, конкурентни и успешни в избраната от тях област.
Oxidative stress and post-stroke depression
Authors: Komsiyska D.
Published: March 2019

The topic of post-stroke depression etiology is reviewed in two main approaches. Some suggest that post-stroke depression is caused by the brain damage itself. On the contrary, others assume that this is a psychologic response to injuries or loss. Many discoveries can be examined as evidence for both the physiological and psychosocial mechanism of post-stroke depression. The two methods are not self-excluding, but instead describe post-stroke depression as a complex and multifactorial disease with interactions between the physiological and environmental factor. One hypothesis about depression occurrence is the inflammatory, oxidative and nitrosative stress (IO&NS) depression theory. Oxidative stress mechanisms are implied in the pathogenesis of mental diseases. The brain is considered particularly vulnerable to oxidative damage, due to its relatively high oxygen utilization and thus generation of free radical subordinate products, its modest antioxidant protections and its lipid-rich resistance.
Az alkalmazott és autonóm rajz összefonódása a képzőművészet határterületein: Liezen-Mayer Sándor két színházi függönytervéről
Authors: Hessky Orsolya
Published: March 2019

Stage curtains are works in the border zone between applied art and high art, having a special place on account of their function and peculiar theme in the oeuvre of some 19th century artists. In that of Sándor Liezen-Mayer the salient places are taken by painting and literary illustration, but in indirect relationship with illustration his commissions to design stage curtains also constituted an organic part of the oeuvre. Designing the program and executing the painted stage curtains was squeezed to the periphery of 19th century painting, whereas in that-time art life it had an important place as an artistic task of great prestige since the late 18th century. With the demotion of allegoric representations into the background the huge surfaces of stage curtains began to feature compositions of a different type, which drew partly on the earlier stock of allegorical elements and partly on literary motifs.

Liezen-Mayer’s contemporary and former colleague at the Academy Hans Makart produced the important pieces of the last great period of curtain decoration, which might have partly been the model for the Hungarian artist, too. Liezen-Mayer’s two curtain designs known today are from the beginning and end of his career, as if framing the oeuvre. The two designs separated by some thirty years are variants of the same allegorical scene: Apollo, the ancient god of arts is seen in an easily interpreted composition, surrounded by diverse attributes and allegorical figures as an illustration of the mythological tradition. Only plans survive of the two – colour schemes and large cartoons –; the comparison of the two provides a firm basis to trace the change in the artist’s outlook over his career.
Professional Preparation and Performance of Preschool Teachers in the Public and Private Schools of Cebu City, Philippines
Authors: Andrin Glenn R. , Etcuban Jonathan O. , Watin Anna Katrina O. , Maluya Robert , Rocha Earl Dave V. , Maulit Alma A.
Published: March 2019

The privilege of instruction is the privilege to get training as well as the opportunity to get training of high quality. Education must be accessible and open additionally adequate and versatile. This study determined the professional preparation and performance of the preschool teachers in public and private schools in Cebu City with the end view of using the findings in designing a Preschool Training Program. The review made utilization of the clear correlational strategy in social affair information from preschool instructors and the school’s principals in Cebu City, Philippines. They are advised to answer the questionnaire for teachers and administrators, and the performance appraisal form for teachers. The study revealed that public preschool teachers have less adequate teaching experience while private preschool teachers have appropriate teaching experience. Additionally, there is a critical distinction in the expert arrangement of the general population and private preschool instructors with the private part of the lead. It was presumed that the general population and private preschool educators have a similar expert arrangement profile and execution. In any case, there is no basic difference in the execution between the overall public and private preschool teachers. The specialists suggest that school overseers ought to direct more administration preparation on preschool training to enhance the instructional skills of their educators.
Importance of Innovation for European SMEs: Perception of Experts
Authors: Arenhardt Daniel Luís , Simonetto Eugênio de Oliveira , Rodrigues Glauco Oliveira
Published: March 2019

Innovation is one of the most important ways in which small and medium-sized enterprises (SMEs) gain competitive advantage, drive the economy and generate new jobs. Many researches have been conducted to determine which practices contribute to the development of innovation in SMEs. However, adoption necessarily requires awareness of its importance to the organization's results. This study is based on data collected from innovation experts based in the European Union with a broad knowledge of the SME reality of that economic bloc. By means of variables constructed from the seven rules of innovation (Davila et al., 2006), the study measured the experts’s opinion on the relevance that SMEs attribute to the factors that lead to innovation, according to the degree of development of their countries. Conversely, SMEs from less developed countries seem more aware of the benefits that innovation can bring to their businesses. Regarding the factors analyzed, (1) incorporation of the concept into the business and (2) innovation alignment with the company strategy were those that presented the best averages, according to experts consulted.
Analysis of the Colombian Medical Tourism Industry from a Systemic Competitiveness Approach
Authors: De la Puente Mario Alberto
Published: March 2019

This research article analyzes the role of the central government of Colombia in the strategy for the improvement of the medical tourism industry through a critical approach of the traditional model of competitiveness. Based on a mixed method, the feasibility of the associative systemic competitiveness model and its effectiveness on the quality of medical services offered to foreign patients is determined. The proposal for the implementation of systemic competitiveness model improves the perception of quality of medical services by foreign patients. In order to implement the proposed model, it is recommended the expansion of free taxation zones, the proliferation of medical service clusters and the strengthening of strategic alliances with international operators.
Design and Validation of a Likert Type Scale to Establish Entrepreneurial Characteristics
Authors: Reyes Juan Luis , Garzón Castrillón Manuel Alfonso , Tapia Sánchez Blanca
Published: March 2019

This article presents the results obtained in the pilot test of an instrument constructed and validated to establish the influence of university curricular training and social, cultural and economic capital in the development of entrepreneurial characteristics. A Likert-type measurement scale was used, which allowed us to establish the relevance of the dimension as a variable of analysis to explain the relationship that exists between the so-called training, social, cultural and economic dimensions in the development of entrepreneur innovation characteristics. propensity to risk, personality, psychological and demographic aspects. Statistical procedures of factorial analysis were used. Two pilot tests were applied; the first one, to a sample of 22 students of the seventh semester; and the second 29 students of sixth and seventh semester of the degree in administration of the Autonomous University of the State of Hidalgo, with the purpose of validating the instrument.
Balances and Alternatives
Authors: Sanabria Landazábal Néstor Juan , Jimenez-Bautista Francisco , Villareal Alejandro
Published: March 2019

Editorial
Economic impact of the museum tourism in Barcelona city
Authors: Miró Alber-Pol
Published: March 2019

The city of Barcelona has become a prime tourist destination thanks to good planning initiated following the Olympic Games in 1992. The Barcelona brand has been consolidating through characteristics such as an important cultural heritage, a situation favorable climatic and significant in the field of fairs and congresses, differentiating it from the rest of the competition both domestic and international investment. One of the points that has been boosted lately has been the cultural tourism, but this is based on the extensive cultural heritage of Barcelona and not in the museum infrastructures. The aim of this study is to provide information on the economic contribution posed by museums to total tourism revenue. From the information provided by the Government of Catalonia, the museums themselves, as well as other studies of matter.ResumenLa ciudad de Barcelona se ha convertido en un destino turístico de primer orden gracias a una buena planificación iniciada a raíz de los Juegos Olímpicos de 1992. La marca Barcelona se ha ido consolidando a través de unas características tales como un importante patrimonio cultural, una situación climática favorable y una inversión considerable en el ámbito de la celebración de ferias y congresos, que la diferencian del resto de la competencia tanto nacional como internacional. Uno de los puntos que se ha potenciado últimamente ha sido el turismo cultural, pero éste se ha basado en el amplio patrimonio cultural de Barcelona y no en las infraestructuras museísticas El objetivo de este estudio es dar información sobre la aportación económica que suponen los museos de la ciudad respecto a los ingresos totales del turismo. A partir de la información suministrada por la Generalitat de Cataluña, los propios museos, así como otros estudios de la materia.ResumoA cidade de Barcelona tornou-se um primo destino turístico graças a um bom planejamento iniciado após os Jogos Olímpicos de 1992. A marca Barcelona tem vindo a consolidar através de características tais como um importante património cultural, uma situação climática favorável e significativa no domínio das feiras e congressos, diferenciando-o do resto da concorrência, tanto o investimento nacional e internacional. Um dos pontos que tem sido impulsionado ultimamente tem sido o turismo cultural, mas isso é baseado na extensa herança cultural de Barcelona e não nas infraestruturas do museu. O objetivo deste estudo é fornecer informações sobre a contribuição econômica representada pelos museus à receita total do turismo. A partir das informações fornecidas pelo Governo da Catalunha, os próprios museus, bem como outros estudos da matéria.
The Security of Socio-Technical Systems
Authors: Kravchenko Sergey
Published: March 2019

The paper deals with the problem of information security of socio-technical systems when developing online applications. The structure of the socio-technical system, its subsystems and the stages of protection the information of such a system are described. The application of the socio-technical approach, its advantages and disadvantages are also studied. The material presented in the paper reveals the approach aimed at improving the efficiency in the development of online applications through the use of social engineering method. The positive factor is the use of feedback by users able to significantly improve existing systems, to reduce the risk of failure of the user from the operation of the remote systems associated with the lack of ease of use and unreliable protection of their personal data. To achieve this goal, we should identify the factors that affect the user’s behavior, as well as prevent users from performing unwanted actions. The creation of an information security system in online applications should help to neutralize the factors that encourage users to use tools to bypass or ignore information security mechanisms. Therefore, the use of social engineering approach in the development of information security systems will contribute to the goal of creating safe and usable applications.
Estimating the Quality of Manageability of the Communication Network for Military Purposes Taking into Account the Requirements of Information Protection
Authors: Shilina Anna , Kuznetsova Valeriya
Published: March 2019

The quality of any purposeful process can be considered as a set of the most essential operational properties that determine its suitability for its intended use. Given the fact that the handling is a characteristic of the communication network, the properties of the management process should be considered from the perspective of the ability of the authorities to implement the tasks in view of the provision of hidden control of troops and weapons. With regard to the study of the quality of communication network management, it is advisable to describe their properties of timeliness (efficiency), effectiveness and resource consumption. At the same time, each of them is complex, has its own structure and is in a certain dependence and relationship with the properties of the system and the properties of the results obtained during its operation. The authors propose the methods for estimating the quality of communication network manageability, describe the properties of efficiency, effectiveness and resource consumption. The quality of decisions is considered in terms of validity, adequacy and protection of information.
Roughening of film fabricated by ultrasonic microarc oxidation on Ti–13Nb–13Zr
Authors: Wang Fengbiao , Wang Yongqing
Published: March 2019

The fracture toughness of brittle biofilms prepared through the microarc oxidation process on the Ti–13Nb–13Zr alloy needs to be improved. The ultrasonic technology was successfully incorporated into the process. The indentation test and its analysis method were adopted to measure the film fracture toughness. The properties of the film such as surface morphology and phase composition were compared with those of a film prepared without using the ultrasonic technology, and the toughening factors were analyzed and a calculation model of fracture mechanics was established. The results show that the composite-process film has higher fracture toughness than the single-process film with a different film porosity, and the toughness of the former can reach 2·65 MPa m1/2 for higher duty cycles. Parts of titanium dioxide (TiO2) phase transformation toughening, reduction of the main-crack stress concentration by microcracks and the densification of the microstructure caused by ultrasonic cavitation effect are the main reasons that fracture toughness improved. Similar results for measurement and calculations obviously indicate the validity of the model. The composite process can achieve the purpose of toughening titanium alloy biofilms.
Status of laser transformation hardening of steel and its alloys: a review
Authors: Babu Purushothaman Dinesh , Marimuthu Ponnusamy
Published: March 2019

The state of laser transformation hardening in surface modification of steel and its alloys is reported in this review paper. The laser hardening process involves the use of high-intensity laser radiation to heat the surface of steel into the austenitic region rapidly. Due to high rates of heat transfer, steep temperature gradients result in rapid cooling by conduction. This causes the transformation from an austenite to a martensite microstructure without the need for external quenching and generates a hard wear-resistant surface. The introduction of high-power lasers, such as neodymium-doped yttrium aluminum garnet (Nd:YAG), diode and fiber lasers, has made laser-assisted hardening an attractive candidate for surface hardening processes. Recently, fiber lasers appeared as a competitor to Nd:YAG and diode lasers for material processing. This review paper is a synopsis of the fundamentals of laser hardening, outlining some of its benefits compared with those of conventional hardening techniques and its industrial applications. A selective review of the experimental and numerical research carried out on steel in this area is also presented. Finally, it is concluded that the overall state of research on laser hardening in surface engineering of steel is well developed, and a still-growing industrial application is observed.
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Authors: AsdDFSDAF Kjhsdkjsa
Published: March 2019

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Tiroglobulin Ölçümlerinin Düsük Titrelerdeki Anti-Tiroglobulinle İnterferansının Arastırılması
Authors: ÇOKLUK Erdem , ŞEKEROĞLU Ramazan , BATİ Bedia , ÖZTURK Mustafa
Published: March 2019

Sonuç:
Bu çalışmanın sonuçları TgAb mevcudiyetinin
düsük titrelerde bile Tg
ölçümlerini önemli oranda interfere ettiğini, dilüsyon oranın bu etkiyi değiştirmediğini göstermektedir.
Ayrıca TgAb dışındaki
diğer otoimmun
antikorların Tg ölçümlerinde interferansa sebep olmadığı ya da çok az olabileceğini söyleyebiliriz.

Bulgu: TgAb
pozitif numunelerdeki recovery sonuçları % 21- % 56 oranında değisirken, TgAb negatif
numunelerininki % 88 - % 96 arasında bulundu.

Gereç-Yöntem:
Bu amaçla düsük
ve yüksek TgAb konsantrasyonuna sahip serum havuzlarından alınan örnekler Tg
standartları içerisine ilave edilerek 1/2, 1/10 ve 1/20 dilüsyonla TgAb
konsantrasyonu 5, 10, 20, 40, 60, 80 ve 100 IU/ml olan numuneler hazırlandı.
Aynı sulandırma işlemi
TgAb negatif serum havuzları için de yapıldı ve örneklerde Tg ölçümleri
yapılarak geri kazanımlar (recovery) hesaplandı.

Amaç:
Tiroglobulin (Tg), tiroid follikülü için spesifik bir marker olarak kullanılır.
Ancak Tg ölçümlerinde ve dolayısıyla klinik olarak değerlendirilmesindeki en
önemli zorluk tiroglobulin antikorlarının (TgAb) sebep olduğu interferanstır.
Yüksek konsantrasyondaki TgAb’ların serum Tg ölçümünü interfere ettiği bilinmektedir. Bu
çalışmada; düsük konsantrasyonda TgAb
bulunan serumların ve negatif TgAb’lu otoimmun tiroiditli hasta serumlarının Tg
standartlarına ilavesinin Tg ölçümü üzerine interferansının araştırılması amaçlandı.
Sense and communicative syncretism of the french advertising discourse in the field of "Produits de luxe"
Authors: Voitenko Mariya
Published: March 2019

Research in the field of advertising discourse is relevant, since advertising plays an important role in the modern society. The meaning content of the advertisement depends on the communicative parameters of the messages, which in their turn are determined by a whole number of extralinguistic factors and contextual conditions. In general, sense is a wide notion, whose search is a permanent problem of humanity. Many scientists have long been trying to give a definition of the sense that would perfectly represent its nature. The article deals with the study of the process of sense generation during communicative interaction between the addresser and the addressee in the French advertising discourse of "luxury goods". While considering the mechanisms of sense generation, the communicative activity of the person is the focus of attention and it "launches" the sense mechanisms of actualization and contextualization. The author uses the three-level classification of operators to analyze the French advertising discourse of "luxury goods" and discribes what kind of communicative actions will happen on each level. The space of discursive senses is elaborated by the valorisation of certain configurations of categorical features, expressed by discursive instances and their relations. The author examines the discursive instances of the I and the Other and illustrates the relations they mostly maintain with different examples of the recent French advertisement in the field of "luxury goods". The article reveals how the communicative syncretism of the French advertising discourse in the field of "luxury goods" manifests itself and what kind of senses this discourse valorizes. Also the attention is paid to the notion of hyperreality and the place which it takes in the French advertising discourse of "luxury goods". Hyperreality is a new linguistic state of society, in which simulation in advertising as a sign system becomes a generator of reality, and through advertisement the society of mass culture and consumption continuously ratifies itself. There is also established the main function of interaction between the discursive instances and detected how the fixation of senses discloses in the French advertising discourse of "luxury goods” on the level of their generalization.
Taras Shevchenko in image strategies of modern Ukraine: linguistic argumentation
Authors: Pliasun Olga
Published: March 2019

The article concentrates on important issues of linguistic imageology – a new direction in the humanities which investigates linguistic peculiarities of image creation. Current research is focused on studying linguistic aspects of image formation in modern mass media which can be done within the framework of an innovative humanitarian discipline – medialinguistic imageology. This newly discovered linguistic branch analyses both linguistic and extralinguistic characteristics of image shaping. Exploring the conceptual apparatus of medialinguistic imageology, the author reveals that a great deal of its notions is of integral nature, i.e. they were borrowed in science from military and political terminology systems. Simultaneously, new concepts in this field are constantly being developed. One of such brand new notions in medialinguistic imageology are concepts “image strategy” and “image strategy of a state”. The author aims to give a comprehensive analysis of these notions in media linguistics. The main objective of the paper is to explore linguistic factors of formation of Ukraine’s national and international image in contemporary mass media. Content analysis of recent publications about Ukraine conducted by the researcher clearly indicates that precedent names of culture play a critical role in the process of creating the image of the state in media. Such prominent figures as Yaroslav the Wise, Bohdan Khmelnytsky, Grigory Skovoroda, Taras Shevchenko etc. are regarded as cultural markers of the country. They are perceived by recipients as certain symbols that form the idea of the Ukrainian culture. The data obtained clearly show that precedent proper name Taras Schevchenko is an essential part of Ukraine’s image campaign, within which the author emphasizes a number of image strategies (i.e. the strategy of universal image, target image strategy, “positioning” strategy, “mythologization” strategy, “emotionalization” strategy, “visualization” strategy, “creative explosion” strategy etc.). The results of the author’s research convince that the appeal to Kobzar as Ukraine’s “business card” can be quite effective in the framework of the Ukrainian image campaign. The findings are of direct practical relevance.
Intertextuality in media texts of genre of interview with politicians. Article 2
Authors: Shulinova Larysa
Published: March 2019

The article continues the research of interviews with Ukrainian politicians from the point of view of the presence of precedent intertexts and their functions. Intertextuality is one of the means of influencing on the recipient, prompting him actively to perceive the text and decode it. The following groups of precedent phenomena are analyzed: precedent names and precedent statements. It has been determined that precedent names are available in replicas of both communicants and are related to relevant precedent situations, texts and quotations. Among them are well-known for the national memory of history, culture: Taras Shevchenko, Mykhailo Hrushevsky; the names of the world-famous politicians, philosophers and religious figures: Mahatma Gandi, O. Solzhenitsyn, Donald Trump, the Holy Bartholomew etc.; the names of Ukrainian politicians, businessmen and political parties, blocs, associations as means of intertextuality can be precedent in the interview texts for all recipients, for certain politicians (one-party or political opponents), for specific situations, a certain period of political history of the country, etc. The author identifies following groups of precedent statements: quotations (direct and indirect), folklorisms (phraseological phrases, anecdotes etc.), book phraseologisms, language clichés and stamps. It has been found that intertext can become an effective mean of realizing of strategic aim – through the implementation of the illocutionary function, that is, refutation/clarification/change/confirmation of primary knowledge, experience and views of the recipient.
De lo formal a lo real. Análisis de la participación familiar en asociaciones de madres y padres y consejos escolares
Authors: Gomariz Vicente María Ángeles , Parra Martínez Joaquín , García Sanz Mari Paz , Hernández Prados María Ángeles
Published: March 2019

La legislación contempla el derecho de las familias a participar desde las Asociaciones de Madres y Padres de Alumnado (AMPA) y el Consejo Escolar (CE). La participación efectiva de las familias en los centros educativos es mejorable en intensidad y en diversidad. Con la finalidad de conocer la participación de las familias en las AMPA y CE y contemplarla en función de la titularidad del centro y la etapa educativa, hemos utilizado 30 ítems de un cuestionario más amplio aplicado a 14876 familias del territorio español. Los resultados arrojan niveles de participación asociados a la AMPA en la mitad de las familias, escaso interés por formar parte de su Junta directiva y una reducida presencia en las actividades organizadas por la asociación, señalando la imposibilidad de conciliación como principal obstáculo. La participación en el CE se mantiene muy baja, alegando la escasa competencia para desarrollar la representación en este órgano. En función de las variables analizadas, la participación normativa de las familias, es significativamente mayor en la etapa de Educación Primaria y en las familias cuyos hijos asisten a centros públicos. No obstante, el tamaño de las diferencias no alcanzó los valores mínimos requeridos.
El desarrollo educativo pedagógico a través de la investigación
Authors: Arce Narváez Gloria Cristina
Published: March 2019

The problem to investigate must be conceivedthrough Questions that will be solved during 1.helnvest1gation process. To cons1der that each problemrequ1res a particular analysls: ot a concrete quest1onon 1.he aspect of the invest1gauon: th1s must needthe hypothesis to verify and to confront in the study:finally the Questions must be formulated consideringlhe times and space contexts of the study to carryout
Maternal pregnancy associated plasma protein-A (PAPP-A) and uterine artery Doppler changes as predictors of pre-eclampsia: a prospective observational study from a teaching hospital in Mysore, Karnataka, India
Authors: Satish Sharanya , Suma K. B. , B. Madhu , M. S. Sujatha
Published: March 2019

Background: Hypertensive disorder affects 10-12% of pregnancies. Identifying women, who are at risk is conducive to prompt gestational management. PAPP-A is a protein complex produced by the developing trophoblasts. Low levels of PAPP-A at 10–14 weeks is a marker of impaired placentation and a smaller placental mass. Doppler imaging permits non-invasive evaluation of the uteroplacental circulation and is invaluable in the management of high-risk pregnancies. The uterine artery Doppler screening identifies patients at risk for developing preeclampsia. To study the association of PAPP-A and the uterine artery Doppler changes as predictor of pre-eclampsia in pregnant women at 11-14 weeks of gestation.Methods: This was a prospective study of 150 pregnant women presenting at 11-14 weeks of gestation for a prenatal check-up. After considering the inclusion and exclusion criteria, serum samples for PAPP-A were assayed. Ultrasound Doppler was used to obtain uterine artery flow velocity waveforms and mean pulsatility index and resistance index of uterine arteries were calculated. Cases were followed up till term and observed for development of pre-eclampsia.Results: 48.6% had low serum PAPP-A levels, in which 77% developed PE. The Mean PI and RI is 2.34±1.16 and 0.58±0.1 respectively. 30% women with abnormal PI values and 24% of women with abnormal RI values developed PE.Conclusions: The combination of maternal history with low serum PAPP-A levels and abnormal uterine artery Doppler at 11-14 weeks can be used as predictor of pre-eclampsia.
WELL LOG DATA INTERPRETATION IN PALEOGEOGRAPHIC RECONSTRUCTIONS (IN THE CASE OF THE BATHONIAN-UPPER JURASSIC DEPOSITS OF SOUTH OF WEST SIBERIA)
Authors: Yan P. A. , Khabarov E. M.
Published: March 2019

According to the results of a comprehensive sedimentological study of the core and well log data, the dissection of the bat-upper Jurassic sediments of the South of the West Siberian oil and gas basin was carried out. Quasi-isochronous marked levels are identified. They are represented by transgressive surfaces, maximum flooding surfaces and extended carbonaceous layers. They are the basis of the performed correlation. A number of characteristic lithological-facies sequences diagnosed by well log data was established.
Myocardial remodeling in rats with metabolic syndrome: role of Rho-kinase mediated insulin resistance.
Authors: Li Chuan-Bao , Li Xiao-Xing , Chen Yu-Guo , Gao Hai-Qing , Bao Cheng-Mei , Liu Xiang-Qun , Bu Pei-Li , Zhang Juan , Zhang Yun , Ji Xiao-Ping
Published: March 2019

Insulin resistance (IR) plays a critical role in metabolic syndrome (MS). Previous studies have demonstrated that activated ROCK is increased in MS patients. However, the effect of Rho-kinase (ROCK) on IR has not been definitely determined. Thus, the aims of the present study were to determine whether ROCK activation induces IR or affects myocardial structure and function, as well as the possible mechanisms underlying this process. Wistar rats fed high fat, high glucose and high salt diet sewed as model of MS and we used transmission electron microscopy, echocardiogram technology, and terminal deoxynucleotidyl transferase-mediated DNA nick-end labeling staining to identify any myocardial damage. The protein levels of MYPT-1 (characteristic of ROCK activation), IRS-1 and AKT were analyzed by immunohistochemistry and Western blotting. In hearts from MS rats, we found increased protein levels of phospho-MYPT-1 and phospho-IRS-1 (Ser307) and decreased phospho-AKT compared to levels in normal rats. In conclusion, the results suggest that ROCK-mediated IR is involved in the development of myocardial impairments in MS rats and that this effect is mediated probably via the IRS-1/PI3-kinase/AKT pathway.
Protective effects of cassia seed ethanol extract against carbon tetrachloride-induced liver injury in mice.
Authors: Xie Qing , Guo Fang-Fang , Zhou Wen
Published: March 2019

Oxidative stress has been recognized as a critical pathogenetic mechanism for the initiation and the progression of hepatic injury in a variety of liver disorders. Antioxidants, including many natural compounds or extracts, have been used to cope with liver disorders. The present study was designed to investigate the hepatoprotective effects of cassia seed ethanol extract (CSE) in carbon tetrachloride (CCl(4))-induced liver injury in mice. The animals were pre-treated with different doses of CSE (0.5, 1.0, 2.0 g/kg body weight) or distilled water for 5 days, then were injected intraperitoneally with CCl(4) (0.1% in corn oil, v/v, 20 ml/kg body weight), and sacrificed at 16 hours after CCl(4) exposure. The serum aminotransferase activities, histopathological changes, hepatic and mitochondrial antioxidant indexes, and cytochrome P450 2E1 (CYP2E1) activities were examined. Consistent with previous studies, acute CCl(4) administration caused great lesion to the liver, shown by the elevation of the serum aminotransferase activities, mitochondria membrane permeability transition (MPT), and the ballooning degeneration of hepatocytes. However, these adverse effects were all significantly inhibited by CSE pretreatment. CCl(4)-induced decrease of the CYP2E1 activity was dose-dependently inhibited by CSE pretreatment. Furthermore, CSE dramatically decreased the hepatic and mitochondrial malondialdehyde (MDA) levels, increased the hepatic and mitochondrial glutathione (GSH) levels, and restored the activities of superoxide dismutase (SOD), glutathione reductase (GR), and glutathione S-transferase (GST). These results suggested that CSE could protect mice against CCl(4)-induced liver injury via enhancement of the antioxidant capacity.
Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis.
Authors: Dziedzic Dariusz , Narajczyk Magdalena , Gabig-Cimińska Magdalena , Jakóbkiewicz-Banecka Joanna
Published: March 2019

It has been demonstrated recently that it is possible to decrease expression of genes coding for enzymes involved in synthesis of glycosaminoglycans (GAGs) by using specific siRNAs which interfere with stability of particular mRNAs. This procedure has been proposed as a potential treatment for patients suffering from mucopolysaccharidoses, a group of inherited metabolic diseases caused by dysfunction of enzymes required for GAG degradation, and resultant storage of these compounds in cells of affected persons. Here, we asked if the simultaneous use two species of specific siRNAs aimed at silencing two genes involved in particular steps of GAG synthesis may be more effective than the use of single siRNA. We found that inhibition of GAG synthesis in cells treated with two siRNAs is generally more effective than using single siRNAs. However, the differences were not statistically significant, therefore the potential benefit from the use of two siRNAs over the use of a single siRNA is doubtful in the light of the cost-benefit ratio and possibly stronger side-effects of the putative therapy.
Agro-food wastes utilization by Blakeslea trispora for carotenoids production.
Authors: Papaioannou Emmanouil H , Liakopoulou-Kyriakides Maria
Published: March 2019

The all-trans-β-carotene is a natural pigment used in various industrial fields (food, cosmetics, pharmaceuticals, etc) and possesses the higher provitamin A activity, in respect to other carotenoids. All-trans-β-carotene is produced industrially by chemical and biotechnological means. For β-carotene biotechnological production in industrial scale mated cultures of Blakeslea trispora, a heterothallic fungus, are mainly used. Despite the intense research for β-carotene production by B. trispora, natural substrate utilization has not been extensively studied. Solid agro-food wastes such as cabbage, watermelon husk and peach peels from northern Greece as main carbon source into submerged B. trispora cultures for carotenoids production, was examined. The media containing only the agro-food waste (2-4) gave a biomass accumulation 7.77 ± 0.4 g/L, while a reference medium 1 with glucose (10 g/L) gave 4.65 ± 0.21 g/L. In another experiments series agro-food wastes were used with corn steep liquor and thiamine (media 6-8), giving a biomass accumulation and total carotenoid volumetric production 10.2 ± 2.41 g/L and 230.49 ± 22.97 mg/L, respectively. These are the higher values reported for solid wastes so far in respect to those obtained from a synthetic medium, with higher glucose concentration of 50 g/L where the correspondent values were 9.41 ± 1.18 g/L and 45.63 mg/L respectively. The results support that B. trispora is able to utilize, almost equivalently, different origin agro-food wastes for carotenoids production. Furthermore, β-carotene percentage in all examined cases was over 76%, as it was estimated by HPLC analysis, suggesting that these agro food wastes may be used for high purity, large scale β carotene production.
Investigatinon of Green Hospital Standards in Jiroft Hospitals
Authors: Mashayekhi Mazar Najme , Ehrampoush Mohammad Hassan , Ebrahimi Ali Asghar , Ghaneian Mohammad Taghi , Dolatabadi Maryam , Asqari Roohollah
Published: March 2019

Introduction: The International Standard Organization created a set of specified standards titled ISO 14000 in 1996 which includes numerous advisory documents related to the environment management, environment supervision, environmental performance evaluation, ecologic labeling, life cycle evaluation and environmental aspects.
Materials and Methods: This is a descriptive-analytical cross sectional study. The population being studied includes the managers and the staff of Jiroft hospitals. The required data are collected using standard questionnaires of environmental management system from 118 managers and staff in various sections of Jiroft hospitals.
Results: The results of the study show that the laboratory, laundry and kitchen condition, water management, contaminants management and spreading to the air, as well as environmental strategies in attaining green hospital standards in Jiroft hospitals, in accordance with ISO 14000, are suitable and at the optimum level.
Conclusion: Hospital and health systems can improve their economic and moral situations in the society by helping to attain the goals of the millennium development in the field of health and stability as well as green economic.
The impact of higher education on employment in the labour market: Lithuanian case
Authors: Bernatonyte Dalia , Ciburiene Jadvyga , Simanaviciene Zaneta , Startiene Grazina
Published: March 2019

This study aims to investigate the employment of higher education in Lithuanian labour market between 2005 and 2014. Today, this problem is relevant to Lithuania, as level of high school graduates employment is changing yearly. The purpose of the research is to evaluate the impact of higher education on employment in Lithuanian labour market. Seeking to define the impact of higher education on employment in Lithuanian labour market, analysis and synthesis of scientific literature about the influence of education on the labour market; systematic statistical data analysis of Lithuanian education and employment and unemployment rate are presented. In order to compare the impact of Lithuanian higher education on employment rate, unemployment rate and real labour productivity with other countries of the EU-28, the correlation analysis are used. Results indicate that education attainment has influence on employment and unemployment level in Lithuanian labour market and relationship between higher education and employment, unemployment and real labour productivity are dominated in all the EU-28 countries.

 

Keywords: education; higher education; employment;  unemployment; labour productivity.
Flash Technique Group Protocol for Highly Dissociative Clients in a Homeless Shelter: A Clinical Report
Authors: Wong Sik-Lam
Published: March 2019

The Flash Technique is a new protocol for use in the preparation phase of eye movement desensitization and reprocessing (EMDR) to quickly reduce the emotional intensity of traumatic memories, prior to full processing with EMDR. This report presents results from a Flash Technique group for five highly dissociative, currently sober addicts in a men's shelter. This group was an attempt to provide an affordable, trauma-focused intervention for the homeless. As part of the intake, each client met individually with the therapist for 30 minutes, to learn to use the flash technique to process a traumatic memory. Three inventories were used to measure treatment outcome: the Short PTSD Rating Interview (SPRINT), the Dissociative Experience Survey (DES-II), and the Beck Depression Inventory-II (BDI-II). Clients filled out the surveys 3 weeks before the start of the group and had their individual sessions 2 weeks before the start of the group. The DES and BDI-II were repeated at the beginning of the eighth session of the group. Clients' surveys showed a decline in scores after seven sessions of therapy: the DES scores dropped from 39.07 (standard deviation [SD] = 23.01) to 20.48 (SD = 10.02) with d = 0.81 and the BDI-II scores dropped from 32.4 (SD = 11.01) to 13.2 (SD = 8.4) with d = 1.74. Pre- and 2-week posttreatment SPRINT surveys showed scores dropping from 28 [SD = 2.05] pretreatment to 15.75 [SD = 5.19] 2 weeks posttreatment, with d = 6.07.