bluuebunny/crossref_metadata_2025 huggingface dataset:
Preparation and investigation of aggregation, fluorescence and singlet oxygen generation properties of gallium and metal-free phthalocyanines
Authors: GÜZEL Emre
Published: September 2018

The synthesis, characterization, aggregation, optical, fluorescence and singlet oxygen generation properties of 2-furylmethoxy substituted gallium and metal-free phthalocyanines (2 and 3, respectively) are reported for the first time. Characterization of the novel synthesized compounds was performed with elemental analysis, ultraviolet-visible spectrophotometry, fourier transform infrared spectrometry, 1H-NMR spectroscopy and mass spectrometry. When the concentration behavior of the synthesized complexes is examined in a certain concentration range in THF, it has been shown that the phthalocyanines predominantly consist of monomeric species. Furyl-containing new phthalocyanines are quite soluble in common organic solvents and this makes them possible to be used in several important applications. Fluorescence behavior of these phthalocyanines were investigated. In this study, the metal ion’s effect on the UV-Vis and photophysical features of the MPcs is also cited. These results show that the metal in the core of the phthalocyanine is an important factor in the fluorescence behavior and quantum yield (ΦF) of the complexes. In singlet oxygen generation studies showed that the phthalocyanines containing the 2-furylmethoxy group indicated a high level of photosensitization and singlet oxygen generation capacity. Consequently, these gallium and metal-free complexes are promising photosensitizer for photodynamic therapy applications.
Análisis coste-beneficio de las estructuras inteligentes = Cost-benefit analysis of intelligent structures
Authors: Ruiz Gorrindo Felix , Martí Colom Pau , Llorens Garcia Ariadna
Published: September 2018

Resumen Definimos estructura inteligente como aquella estructura dotada de unos sensores (en especial continuos y de fibra óptica), de manera que es capaz de transmitir datos de interés sobre su estado de salud (deformaciones, fisuraciones, oxidaciones, etc.). Esta tecnología puede facilitar el mantenimiento preventivo de los edificios y la gestión de su salud estructural. Por ello, un aspecto de interés necesario a analizar para saber si la tecnología es aplicable o no, es evaluar su rentabilidad. Así, el objeto de este artículo es realizar un análisis coste-beneficio de las estructuras inteligentes, estudiando por un lado cuál es el incremento de coste inicial que supone la implementación de la propuesta, y por otro lado evaluar cuál es el ahorro de dinero a lo largo del tiempo que supone la aplicación de la misma, lo que permite establecer el periodo de retorno de la inversión inicial, y a partir de qué momento se pueden esperar beneficios netos. Abstract Smart structure is defined as that structure equipped with sensors (especially continuous and composed of fiber optic), so that it is capable of transmitting data of interest about its state of health (deformations, cracks, oxidations, etc.). This technology can facilitate the preventive maintenance of buildings and the management of their structural health. Therefore, an aspect of interest necessary to analyze in order to know if the technology is applicable or not, is to evaluate its profitability. Thus, the objective of this article is to perform a cost-benefit analysis of smart structures, studying on the one hand which is the initial cost increase involved in the implementation of the proposal, and on the other hand to evaluate which is the saving of money to over the time that the application of it represents, what allows to establish the payback period of the initial investment, and from which moment you can expect net benefits.
Sistema inteligente, sostenible e integrado de gestión de estructuras = Intelligent, sustainable and integrated structure management system
Authors: Muñoz O. , Sánchez J.C. , Capelastegui A. , Pérez J. , Pérez J.A. , López P.L.
Published: September 2018

Resumen El sistema de monitorización remota Infrasmart diseñado por Tecnalia es usado como base para el desarrollo de supervisión de infraestructuras civiles tanto existentes como de nueva construcción en donde el despliegue de la instalación debe de ser lo menos intrusiva posible. Para conseguir su objetivo el sistema se basa en módulos de adquisición distribuidos con capacidad de comunicación inalámbrica de larga distancia y auto-alimentación orientada a la eliminación del cableado propio de este tipo de instalaciones. A su vez el concentrador de datos gestiona la recepción de la información de dichos módulos y la evacuación de los mismos a un servidor de datos seguro orientado a la supervisión remota de la infraestructura. Actualmente la capacidad de medida de los nodos de adquisición abarca tanto medidas cuasi-estáticas, (sensores de temperatura e hilo vibrante), como medidas dinámicas accionadas por evento, (acelerómetros). En adición existe la capacidad de integrar nuevos sensores conforme a nuevas especificaciones dando como resultado un sistema abierto y escalable en función de los parámetros de interés de la infraestructura a monitorizar. Abstract The Infrasmart remote monitoring system designed by Tecnalia is used as a basis for the development of supervision of both existing and new construction civil infrastructures where the deployment of the installation should be as unobtrusive as possible. To achieve its objective, the system is based on distributed acquisition modules with long-distance wireless communication capability and self-feeding aimed at eliminating the wiring of these types of installations. At the same time, the data concentrator manages the reception of the information of said modules and the evacuation thereof to a secure data server oriented to the remote supervision of the infrastructure. Currently, the measurement capacity of the acquisition nodes includes both quasi-static measures (temperature sensors and vibrating wire), and dynamic measurements driven by events (accelerometers). In addition, there is the ability to integrate new sensors according to new specifications resulting in an open and scalable system depending on the parameters of interest of the infrastructure to be monitored.
Uncovering the Morphology of Kōm ad-Dikka in Alexandria
Authors: Damir Mirhan
Published: September 2018

The historical residential area of Kōm ad–Dikka in Alexandria has experienced subsequent morphological transformation since the ancient era until present. Each historical period had a physical impact on the city’s urban structure that in turn struggled to survive its successive one with its different urban conception. However, the sinuous streets of this area, which probably date back to the late Egyptian Medieval period, are characterized as the only surviving organic fabric intra–muros that was not altered during the Egyptian Modern period. This paper elaborately investigated the chronological history of the historical residential area since the ancient era until the mid—twentieth century. Based on in–depth investigation of historical maps and memoirs, it revealed the possible reasons behind its extant sinuous urban form and postulated reconstructions of its urban morphology through sequential phases.
Transcriptomics as Precision Medicine to Classify In Vivo Models of Dietary-Induced Atherosclerosis at Cellular and Molecular Levels
Authors: Evsikov Alexei , Marín de Evsikova Caralina
Published: September 2018

The central promise of personalized medicine is individualized treatments that target molecular mechanisms underlying the physiological changes and symptoms arising from disease. We demonstrate a bioinformatics analysis pipeline as a proof-of-principle to test the feasibility and practicality of comparative transcriptomics to classify two of the most popular in vivo diet-induced models of coronary atherosclerosis, apolipoprotein E null mice and New Zealand White rabbits. Transcriptomics analyses indicate the two models extensively share dysregulated genes albeit with some unique pathways. For instance, while both models have alterations in the mitochondrion, the biochemical pathway analysis revealed, Complex IV in the electron transfer chain is higher in mice, whereas the rest of the electron transfer chain components are higher in the rabbits. Several fatty acids anabolic pathways are expressed higher in mice, whereas fatty acids and lipids degradation pathways are higher in rabbits. This reflects the differences between two translational models of atherosclerosis. This study validates transcriptome analysis as a potential method to precisely identify altered cellular and molecular pathways in atherosclerotic disease, which can be used to individualize treatment even in the absence of genetic data.
Deep Learning with Unsupervised Data Labeling for Weeds Detection on UAV Images
Authors: Bah M  Dian , Hafiane Adel , Canals Raphael
Published: September 2018

In recent years, weeds is responsible for most of the agricultural yield losses. To deal with this threat, farmers resort to spraying pesticides throughout the field. Such method not only requires huge quantities of herbicides but impact environment and humans health. One way to reduce the cost and environmental impact is to allocate the right doses of herbicide at the right place and at the right time (Precision Agriculture). Nowadays, Unmanned Aerial Vehicle (UAV) is becoming an interesting acquisition system for weeds localization and management due to its ability to obtain the images of the entire agricultural field with a very high spatial resolution and at low cost. Despite the important advances in UAV acquisition systems, automatic weeds detection remains a challenging problem because of its strong similarity with the crops. Recently Deep Learning approach has shown impressive results in different complex classification problem. However, this approach needs a certain amount of training data but, creating large agricultural datasets with pixel-level annotations by expert is an extremely time consuming task. In this paper, we propose a novel fully automatic learning method using Convolutional Neuronal Networks (CNNs) with unsupervised training dataset collection for weeds detection from UAV images. The proposed method consists in three main phases. First we automatically detect the crop lines and using them to identify the interline weeds. In the second phase, interline weeds are used to constitute the training dataset. Finally, we performed CNNs on this dataset to build a model able to detect the crop and weeds in the images. The results obtained are comparable to the traditional supervised training data labeling. The accuracy gaps are 1.5% in the spinach field and 6% in the bean field.
Perspectives from Montiaceae (Portulacineae) Evolution. I. Phylogeny and Phylogeography
Authors: Hershkovitz Mark A.
Published: September 2018

Montiaceae comprise a clade of at least 270 species plus about 20 accepted subspecific taxa, primarily of western America and Australia. The present paper is the first of a two-part work that seeks to evaluate evolutionary theory via metadata analysis of Montiaceae. In particular, it uses metadata analysis to evaluate the theory in theory-laden methods that have been applied in evolutionary analyses of Montiaceae. This part focuses on phylogeny and phylogeography. The second part focuses on phenotypic and ecological diversification. An emergent theme in this paper is the degree to which historical idiosyncrasy during Montiaceae evolution misleads quantitative methods of evolutionary reconstruction and phylogeographic interpretation. This suggests that idiosyncraticity itself is a fundamental property of evolution. The second part of this work elaborates this notion as the Principle of Evolutionary Idiosyncraticity. The present part describes idiosyncraticity in molecular phylogenetic and phylogeographic data and uses this notion to refine ideas on Montiaceae evolution. Phylogenetic metadata conflicts and conflicting phylogeographic interpretations are discussed. I conclude that, owing to PEI, quantitative methods of evolutionary analysis cannot be globally accurate, though they are useful heuristically. In contrast, classical narrative analysis is robust in the face of PEI.
Possible Unification of Quantum Mechanics and General Relativity Theory Based on the Three-Dimensional Quantized Spaces
Authors: Hwang Jae-Kwang
Published: September 2018

Three-dimensional quantized space model is newly introduced. Quantum mechanics and relativity theory are explained in terms of the warped three-dimensional quantized spaces with the quantum time width (Dt=tq). The energy is newly defined as the 4-dimensional space-time volume of E = cDtDV in the present work. It is shown that the wave function of the quantum mechanics is closely related to the warped quantized space shape with the space time-volume. The quantum entanglement and quantum wave function collapse are explained additionally. The special relativity theory is separated into the energy transition associated with the space-time shape transition of the matter and the momentum transition associated with the space-time location transition. Then, the quantum mechanics and the general relativity theory are about the 4-dimensional space-time volume and the 4-dimensional space-time distance, respectively.
Analytical Modeling of Three-Dimensional Temperature Distribution of Selective Laser Melting of Ti-6Al-4V
Authors: Ning Jinqiang , Liang Steven Y.
Published: September 2018

Selective laser melting (SLM) is one of the widely used techniques in metallic additive manufacturing, in which high-density laser powder is utilized to selectively melting layers of powders to create geometrically complex parts. Temperature distribution and molten pool geometry directly determine the balling effect, and concentrated balling phenomenon significantly deteriorates surface integrity and mechanical properties of the part. Finite element models have been developed to predict temperature distribution and molten pool geometry, but they were computationally expensive. In this paper, the three-dimensional temperature distributions are predicted by analytical models using point moving heat source and semi-ellipsoidal moving source respectively. The molten pool dimensions under various process conditions are obtained from the three-dimensional temperature predictions and experimentally validated. Ti-6Al-4V alloy is chosen for the investigation. Good agreements between the predictions and the measurements are observed. The presented models are also suitable for other metallic materials in the SLM process.
Oxidation of Methionine 77 in Calmodulin Alters Mouse Development and Behavior
Authors: Marimoutou Méry , Springer Danielle A. , Liu Chengyu , Kim Geumsoo , Levine Rodney
Published: September 2018

Methionine 77 in calmodulin can be stereospecifically oxidized to methionine sulfoxide by mammalian methionine sulfoxide reductase A. Whether this has in vivo significance is unknown. We therefore created a mutant mouse in which wild-type calmodulin-1 was replaced by a calmodulin containing a mimic of methionine sulfoxide at residue 77. Total calmodulin levels were unchanged in the homozygous M77Q mutant, which is viable and fertile. No differences were observed on learning tests, including the Morris water maze and associative learning. Cardiac stress test results were also the same for mutant and wild type mice. .However, young male and female mice were 20% smaller than wild type mice, although food intake was normal for their weight. Young M77Q mice were notably more active and exploratory than wild type mice. This behavior difference was objectively documented on the treadmill and open field tests. The mutant mice ran 20% longer on the treadmill than controls, and in the open field test, the mutant mice explored more than controls and exhibited reduced anxiety These phenotypic differences bore a similarity to those observed in mice lacking calcium/calmodulin kinase Iiα (CaMKIIα). We then showed that M77Q calmodulin was less effective in activating CaMKIIα than wild type calmodulin. Thus, characterization of the phenotype of a mouse expressing a constitutively active mimic of calmodulin led to the identification of the first calmodulin target that can be differentially regulated by the oxidation state of Met77. We conclude that reversible oxidation of methionine 77 in calmodulin by MSRA can regulate cellular function.
Statistical Mechanics of On-Line Learning Under Concept Drift
Authors: Straat Michiel , Abadi Fthi , Göpfert Christina , Hammer Barbara , Biehl Michael
Published: September 2018

We introduce a modelling framework for the investigation of on-line machine learning processes in non-stationary environments. We exemplify the approach in terms of two specific model situations: In the first, we consider the learning of a classification scheme from clustered data by means of prototype-based Learning Vector Quantization (LVQ). In the second, we study the training of layered neural networks with sigmoidal activations for the purpose of regression. In both cases, the target, i.e. the classification or regression scheme, is considered to change continuously while the system is trained from a stream of labeled data. We extend and apply methods borrowed from statistical physics which have been used frequently for the exact description of training dynamics in stationary environments. Extensions of the approach allow for the computation of typical learning curves in the presence of concept drift in a variety of model situations. First results are presented and discussed for stochastic drift processes in classification and regression problems. They indicate that LVQ is capable of tracking a classification scheme under drift to a non-trivial extent. Furthermore, we show that concept drift can cause the persistence of sub-optimal plateau states in gradient based training of layered neural networks for regression.
Determination of Material Characteristics and Shear Wave Velocity of Volcanic Sediment Layer of Mount Samalas Using MASW Technique
Authors: Hiden Hiden , Ardianto Teguh , Minardi Suhayat , Taurida Alfina , Muhajirah Muhajirah
Published: September 2018

The application of geophysical methods for the characterization of geomorphologic subsurface features has become very popular in recent years. Convential geophysical applications on undifferentiated and weathered slopes have been less effective. Multichannel analysis of surface waves (MASW) is a new hope for the solution of the problem. MASW methods was used to the first step in order to reconstruct the ancient eruption of Mount Samalas. MASW was applied to the remnants of ancient volcanic sediment on Lombok Island to determine the physical and physical characteristics of seismic subsurface features. This paper is also discussion the application's capabilities of the MASW method on undifferentiated and weathered volcanic deposits on the slope area and classified them. The results of the research show that MASW technique is powerful in characterizing and delineating the stratum of the layers of undifferentiated and weathered volcanic precipitation areas. MASW is able to predict subsurface structures, especially for shallow and thin layers and presenting site class information for internal structure (vertical resolution). Based on S wave velocity structure, undifferentiated and weathered volcanic layer, genes are classified into site class C, D, and E. In the future, this method will completed with combination of other geophysical method and parameters variation (frequency and spaces) for isopach mapping of volcanic sediment and then analysis of ancient volcanic eruption dynamics.
Spatial and Age Related Effects on Phytochemical Compounds of Ethanolic Extract of Gigantochloa scortechinii Rhizome
Authors: Mohamed Johar , Abdul Hamid Hazandy , Nuruddin Ahmad Ainuddin , Nik Abdul Majid Nik Muhammad
Published: September 2018

This study was designed to assess variation of possible phytochemical compounds in the ethanolic extracts of Gigantochloa scortechinii rhizome. Destructive sampling was done by using selective random sampling method on four consecutive rhizomes from healthy clumps and was conducted at two natural forests and one secondary forest (planted). Homogenized sample were extracted using solvent extraction (70% ethanol) method. Ethanolic extracts of G. scortechinii rhizome were qualitatively analyzed using GC/MS GC2010 Plus, Shimadzu to determine the composition of phytochemical compounds and identified using FFNSC 1.3, NIST11, PMW_tox2, and Wiley229 spectral library. A qualitative variation was observed with a total of 56 compounds were identified and differentiated between study site and rhizome age. Results revealed that G. scortechinii rhizome contains various phytochemical compounds with potential as a plant of phytopharmaceutical importance. This is the first finding on the spatial and age-related effects of phytochemical compounds in a consecutive rhizome and of G. scortechinii rhizome specifically.
A Coalition Formation Game Approach for Efficient Cooperative Multi-UAV Deployment
Authors: Ruan Lang , Chen Jin , Guo Qiuju , Jiang Han , Zhang Yuli , Liu Dianxiong
Published: September 2018

UAV cooperative control has been an important issue in UAV-assisted sensor network, thanks to the considerable benefit obtained from cooperative mechanism of UAVs being applied as a flying base station. In coverage scenario, the tradeoff between coverage performance and transmission performance often makes deployment of UAVs fall into a dilemma, since both indexes are related to the distance between UAVs. To address this issue, UAV coverage and data transmission mechanism is analyzed in this paper, then an efficient multi-UAV cooperative deployment model is proposed. The problem is also modeled as a coalition formation game (CFG). The CFG with Pareto order is proved to have a stable partition. Then, an effective approach consisting of coverage deployment and coalition selection is designed, wherein UAVs can decide strategies cooperatively to achieve better coverage performance. Combining analysis of game approach, a coalition selection and position deployment algorithm based on Pareto order (CSPDA-PO) is designed to execute coverage deployment and coalition selection. Finally, simulation results are shown to validate the proposed approach based on efficient multi-UAV cooperative deployment model.
Rap1 Regulates Hepatic Stellate Cell Migration through the Modulation of RhoA Activity in Response to Transforming Growth Factor-β1
Authors: Moon Mi-Young , Kim Hee-Jun , Kim Mo-Jong , Uhm Sunho , Park Ji-Won , Suk Ki-Tae , Park Jae-Bong , Kim Dong-Jun , Kim Sung-Eun
Published: September 2018

Although the migration of hepatic stellate cells (HSCs) is important for hepatic fibrosis, the regulation of HSC migration is poorly understood. Interestingly, transforming growth factor (TGF)-β1 induces monocyte migration to sites of injury or inflammation in the early phase but inhibits cell migration in the late phase. In this study, we investigated the role of RhoA signaling in TGF-β1-induced HSC migration. We found that TGF-β1 increased the protein and mRNA levels of α-SMA and collagen type I in HSC-T6 cells. The level of RhoA-GTP in TGF-β1-stimulated cells was significantly higher than that in control cells. Moreover, cofilin phosphorylation and F-actin formation was more strongly detected in TGF-β1-stimulated cells than in control cells. Additionally, TGF-β1 induced the activation of NF-κB and the expression of extracellular matrix proteins and several cytokines in HSC-T6 cells. The active form of Rap1 (Rap1 V12) suppressed RhoA-GTP levels, whereas the dominant negative form of Rap1 (Rap1 N17) augmented RhoA-GTP levels. Therefore, we confirmed that Rap1 regulates RhoA activation in TGF-β1-stimulated HSC-T6 cells. These findings suggest that TGF-β1 regulates Rap1, resulting in RhoA suppression, NF-κB activation and F-actin formation during the migration of HSCs.
Advantages and Limitations to the Use of Optical Measurements to Study Sediment Dynamics
Authors: Boss Emmanuel , Sherwood Christopher , Hill Paul , Milligan Tim
Published: September 2018

Measurements of optical properties have been used for decades to study particle distributions in the ocean. They have been found useful to constrain suspended mass concentration as well as particle-related properties such as size, composition, packing (particle porosity or density) and settling velocity. Optical properties, however, provide measurements that are biased, as certain particles (based on size, composition, shape or packing) contribute to a specific property more than others. Here we study this issue both theoretically as well as by contrasting different optical properties collected simultaneously in a bottom boundary layer, to highlight the utility of such measurements as well as the biases we are likely to encounter using different optical properties to study suspended particles. In particular, we investigate the possibility to infer settling velocity from vertical profiles of optical measurements, finding that the effects of aggregation dynamics can seldom be ignored.
Optimization of Radiators, Underfloor and Ceiling Heating towards the Definition of a Reference Ideal Heater for Energy Efficient Buildings
Authors: Ferrantelli Andrea , Võsa Karl-Villem , Kurnitski Jarek
Published: September 2018

Heat emitters constitute the primary devices used in space heating and cover a fundamental role in the energy efficient use of buildings. In the search for an optimized design, heating devices should be compared with a benchmark emitter with maximum heat emission efficiency. However, such an ideal heater still needs to be defined. In this paper we perform an analysis of heat transfer in a European reference room, considering room side effects of thermal radiation and computing the induced operative temperature both analytically and numerically. By means of functional optimization, we analyse trends such as the variation of operative temperature with radiator panel dimensions, finding optimal configurations. In order to make our definitions as general as possible, we address panel radiators, convectors, underfloor (UFH) and ceiling heating. We obtain analytical formulas for the operative temperature induced by panel radiators and identify the 10-type as our ideal radiator, while the UFH provides the best performance overall. Regarding specifically UFH and ceiling heaters, we find optimal sizes that identify the according ideal emitters. The analytical method and quantitative results reported in this paper can be generalized and adopted in most studies concerning the efficiency of different heat emitter types in building enclosures.
IMPORTANCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION DETECTION IN FEMALE RENAL TRANSPLANT RECIPIENTS IN THE FIRST YEAR AFTER TRANSPLANTATION
Authors: Cistjakovs Maksims , Sultanova Alina , Jermakova Olga , Sokolovska Liba , Chapenko Svetlana , Lesina-Korne Baiba , Rozental Rafail , Murovska Modra , Ziedina Ieva
Published: September 2018

OBJECTIVES: Most of human papilomavirus (HPV) infections are “cleared” by the immune system, however, in cases of immune system suppression infections could lead to development of malignancies. The aim of this study was to find out the frequency of HR-HPV infection in early period after renal transplantation in Latvian recipients receiving immunosuppressive therapy and to follow the progression of the infection up to one year.
METHODS: 43 female renal recipients (median age of 48 IQR= 39-58) and 79 practically healthy female individuals (median age of 48 IQR= 42-57) as a control group were enrolled in this investigation. For the detection of HPV infection patients' samples (blood and vaginal swabs) where collected two weeks after transplantation with following collection of six months and one year. Different polymerase chain reactions for HR-HPV genomic sequences detection and commercial ELISA kit for detection of anti-HPV IgG antibodies were used.
RESULTS: In this study we show that frequency rate of HR-HPV infection has increased by the one year after transplantation from early stage of immumosuppressive therapy (from 24% to 36%). Also increase of HR-HPV load was detected over the time, showing the highest median viral load at sixth month after transplantation.
CONCLUSIONS: From the obtained data follows that it is very important to carefully monitor patients receiving immunosuppression therapy on progression of HR-HPV. In the case of this viral infection presence, immunosuppressive therapy must be attentively adjusted to avoid the HR-HPV infection rapid progression with the subsequent development of CIN or cervical cancer.
An Effective FCM Approach of Similarity and Dissimilarity Measures with Alpha-Cut
Authors: Mukhopadhaya Sayan , Kumar Anil , Stein Alfred
Published: September 2018

In this study, the fuzzy c- means classifier has been studied with nine other similarity and dissimilarity measures: Manhattan distance, chessboard distance, Bray-Curtis distance, Canberra, Cosine distance, correlation distance, mean absolute difference, median absolute difference and normalised squared Euclidean distance. Both single and composite modes were used with a varying weight constant (m) and also at different α-cuts. The two best single norms obtained were combined to study the effect of composite norms on the datasets used. An image to image accuracy check was conducted to assess the accuracy of the classified images. Fuzzy Error Matrix (FERM) was applied to measure the accuracy assessment outcomes for a Landsat-8 dataset with respect to the Formosat-2 dataset. To conclude FCM classifier with Cosine norm performed better than the conventional Euclidean norm. But, due to the incapability of the FCM classifier to handle noise properly, the classification accuracy was around 75%.
Análise Mecânica de Resíduos de Construção e Demolição por meio de Ensaios Empíricos e Mecanísticos
Authors: Lima Mayara Da Silva , Dos Santos Thaís Cavalcante , Bastos Juceline Batista dos Santos , Farias Teresa Raquel Lima
Published: September 2018

Tendo em vista as vantagens técnicas, econômicas e socioambientais que o agregado reciclado pode oferecer e a busca por materiais alternativos que apresentem características adequadas para utilização em camadas de pavimentos rodoviários, nesta pesquisa buscou-se avaliar a viabilidade do uso de Resíduos da Construção e Demolição (RCD) em camadas de pavimentos. Para tanto, o comportamento mecânico de três materiais foi avaliado, sendo um RCD puro, um solo natural e o mesmo solo estabilizado com RCD na proporção de 50%. Foram realizados ensaios de: caracterização, compactação com emprego de diferentes energias, determinação do Índice de Suporte Califórnia (CBR) e Módulo de Resiliência (MR). A análise granulométrica demonstrou que o RCD e o solo apresentaram, respectivamente, características predominantemente pedregulhosa (51,4%) e arenosa (69,8%). Ambas as amostras (RCD e solo) foram classificadas como A-1-b, classificação da AASHTO. Os resultados do estudo sugerem a necessidade de uma maior energia de compactação nas camadas granulares estabilizadas com RCD, tendo em vista o significativo incremento proporcionado aos valores de CBR obtidos com o aumento da energia (com valores de aproximadamente 20% na energia intermediária, superou 140% na energia modificada). Os valores de CBR e MR indicaram a viabilidade técnica do RCD puro e do solo estabilizado com RCD, para ser empregado em camadas de bases, visto o comportamento mecânico desses materiais, a compatibilidade com os agregados convencionais e o atendimento às especificações para uso em pavimentos rodoviários.
Concepções dos Estudantes de uma Escola Estadual do Ceará/Brasil a respeito das Implicações da Implantação de um Projeto de Saneamento Básico
Authors: Vasconcelos Erlândia Marcia , De Sousa Regina Maria , Cavalcante Elizabeth De Araújo , Benevides Jorgeana De Almeida Jorge , Almeida Alisandra Cavalcante Fernandes de , Farias Wanglêsio Silveira de
Published: September 2018

O meio ambiente, por ser um sistema coletivo, é alvo de estudos que analisam os impactos que a atividade humana pode causar aos seres que o habitam, principalmente no que diz respeito à saúde. Assim, o saneamento básico passou a ser uma etapa fundamental no planejamento das cidades. No entanto, a sociedade desconhece as atividades desse serviço, não dando a devida importância e agindo por conta própria no que diz respeito à construção de fossas e ao descarte do lixo. O município de Cruz, Ceará, passa pela fase de implantação de uma obra de saneamento básico. Todavia, os moradores têm pouco acesso a fontes de informações sobre os benefícios desse serviço. Diante disso, a escola tem papel fundamental na formação do conhecimento, uma vez que as informações nela adquiridas, podem se tornar um ciclo contínuo de aprendizagem entre escola e comunidade. Este trabalho trata de um estudo de caso que objetiva avaliar o conhecimento dos discentes de uma escola estadual do município de Cruz a respeito das implicações do projeto de saneamento básico em execução na cidade, bem como sensibilizá-los de sua importância. A pesquisa ocorreu no período de agosto a outubro de 2016, envolveu 502 estudantes, dividindo-se em duas fases: aplicação de questionários para avaliar o conhecimento prévio dos discentes e aplicação de palestras, seguido de questionários para a avaliação do aprendizado. A partir dos dados obtidos, 91% dos estudantes demonstraram retorno positivo do aprendizado após a intervenção, o que evidencia a necessidade de ações como essas na escola.
NAJSTARSZE HEBRAJSKIE INSKRYPCJE ALFABETYCZNE (ANALIZA EPIGRAFICZNA)
Authors: Nowogórski Przemysław
Published: September 2018

Today, science has six of the oldest Hebrew alphabetic inscriptions: ostracon from ʼIzbet Ṣartah (about 1200 BC), inscription from Tel Zayit (/ 11th / half of 10th century BC), ostracon from Chirbet Qeiyafa (decline 11th - the first half of 10th century BC – reign of Saul ); a new inscription from Chirbet Qeiyafa (dated as the previous one); new ostracon form Ophel, Jerusalem (11th or half of 10th BC – reign of Solomon, it is also the oldest Hebrew inscription from the area of Jerusalem); Gezer Calendar (second half of 10th BC – reign of Solomon or the first half of the ninth century BC). This article discusses the contemporary state of research on early Hebrew inscriptions. It also presents the author's own findings and related issues on ancient Hebrew epigraphic.
„NEC TEMERE NEQUE INIUSTE, SED CONSULTO ET AEQUITATIS DUCTU IN HANC TERRAM TRANSVECTUS SUM” (GG II, 12) – LEGITYMIZOWANIE WŁADZY W GESTA GUILLELMI WILHELMA Z POITIERS
Authors: Dżwigała Bartłomiej
Published: September 2018

The aim of the article is to analyse first medieval biography of William the Conqueror in order to explain the issue of legitimization of the Norman rule in England. In the introduction I present the author of Gesta Guillelmi and his work. Main part of the article contains detailed explanatory narrative’s elements used by author to provide ideological justifications for William the Conqueror’s rule in London.
L’EDUCAZIONE DELLE RAGAZZE NEL XIV SECOLO SECONDO FRANCESCO DA BARBERINO
Authors: Głusiuk Anna
Published: September 2018

Francis from Barberino is an author of one of the few female etiquette texts composed in the Middle Ages. In this period, writers wrote some texts about dress etiquette but the most of them was dedicated to the male reader and there are only some text written for women.In his works, Barberino shows the dress etiquette appropriate for a girl at the age of marriage coming from a family of high social status. Thanks to his work, it is possible to see which virtues was appreciated, what was allowed and which behaviors was not accepted by the society of that time.
SZLACHTA A DUCHOWIEŃSTWO NA SEJMACH W LATACH CZTERDZIESTYCH I PIĘĆDZIESIĄTYCH XVI WIEKU
Authors: Godlewski Łukasz
Published: September 2018

The Executionist movement’s programme from the beginning of its existence revoked the privileges of the clergy not only in the legal but also in the economic field. The Chamber of Deputies wanted: the clerical estate holders to perform military service, the abolition of tithes, the taxation of the church, to devote “annats” to the defense of the country and jurisdictional demarcation between secular and ecclesiastical courts . The Chamber of Deputies, fighting against the clergy favored by the king, unified their demands in order to act boldly in defense of their rights and gain new privileges. The final demands of the Executionist movement were formulated during the development of the Reformation and the transitional period caused by the change of the monarchs in the Republic of Nobles. The cumulation of these mechanisms in the middle of the 16th century not only stimulated the development and power of the Executionist movement but also intensified the conflict of interest between the clergy and nobility. The progress of the Reformation was accompanied by a growing dissatisfaction with the jurisdiction of the ecclesiastical courts over the nobility. The Chamber of Deputies formulated their suppositions depending on the situation outside and inside the country. The bishops failed to enforce the execution of judgments of the ecclesiastical courts. However, the right of sole judicial powers to pass verdicts connected with faith and religion were not taken away from the clergymen. It was just the opposite. Zygmunt August approved this privilege of the priests and at the same time executing verdicts on peerage was suspended. This case was, however, not completed and that is why succeeding parliaments worked on it furhter. The representatives of gentry did not manage to tax the income of church, despite serious efforts to do so. The king tried persistently to unite both political camps. However, the overextending of the whole Executionist program by the representatives prevented the achieving of a compromise or any similar outcome.
ODRODZENIE NAMYSŁOWSKIEGO KLASZTORU FRANCISZKAŃSKIEGO W XVII WIEKU W ŚWIETLE PIERWSZEGO ROZDZIAŁU KRONIKI KONWENTU
Authors: Musiał Marcin
Published: September 2018

The goal of this study is, on the one hand, to outline the circumstances leading to formation of the convent of Reformed Franciscans in Namysłów in 1675, and on the other hand, to show the way of conducting historiographical narrative in the chronicle sources of Reformed Franciscans. This issue is particularly interesting in the context of repossession activities, which have been conducted by the St. Wenceslaus’ Czech province of Reformed Franciscans since the beginning of the 17th century, aiming at the return of observance monasteries confiscated in the era of the Reformation and, in this way, rebuilding the structures of the province. The goal of systematized vision of the past was, on the one hand, to consolidate the young province, on the other hand, to demonstrate historical rights of Czech Reformed Franciscans to particular monastic houses. An example of such narrative, coordinated by one of the provincials, Fr Bernard Sannig, is a chronicle of the convent of Reformed Franciscans in Namysłów, which was, with 9 other monasteries, a Silesian part of Czech province.
ECHA WYDARZEŃ ZE ŚWIATA ZEWNĘTRZNEGO NA KARTACH KRONIKI ZOFII GROTHÓWNY Z LAT 1703-1741
Authors: Mierzejewska Milena
Published: September 2018

The article describes the echoes of events from the outside world in an enclosed Norbertine convent in Imbramowice and is mainly based on records taken from The Chronicle of Sophia Grothówna from the years 1703-1741. Although the Norbertine monastery was (and still is) enclosed, it maintained communications with the outside world on a regular basis but unwillingly. This article discusses just such situations. Sisters had to contend with numerous military invasions, requesting ever larger contributions and looting the surroundings belonging to the nuns’ granges. During the wars of the seventeenth century a number of plague broke out, which reached the surrounding areas in Imbarmowice. The peasants contracted the plague from the army. In other events, there were the outbreak of fires, the largest broke out in 1704, and many sisters had to leave the monastery and move to other monasteries or return to their homes. The reconstruction of the monastery took almost 20 years. The article describes information about the floods, strong winds, hunger, cold and drought that ravaged the monastery and caused major damage in convent farms.
BRACIA TUŁODZIECCY – PRZYCZYNEK DO BIOGRAFII
Authors: Dobrzeniecka Monika
Published: September 2018

The aim of the article is to portray the heroes of Sierpc from the first half of 20th century: Henry, Edward and Felician Tulodziecki. It comprises a synopsis of their activity in the fields of education and politics, including their participation in the structures of Polish Socialist Party.
Męczeństwo za wiarę garnizonu z Gazy w okresie wczesnych podbojów muzułmańskich w świetle Opisu męczeństwa sześćdziesięciu męczenników z Gazy
Authors: Karczewski Łukasz
Published: September 2018

Acts of sixty martyrs of Gaza is a Latin translation of the original text,  describing conquest of Gaza and martyrology of Christian soldiers who died in name of Christian faith. There is little information describing  capture of the garrison in VIIth century, thus the passion of Gaza martyrs is one of the few sources describing that event, allowing us to recreate the dramatic turn of events back then. It also describes Muslims attitude toward Christians in the middle east. The Author tries to identify the anonymous soldiers of Gaza Garrison who later gave their lives at the hands of Muslim conquerors because of they refuse to abandon Christianity.
Napoleońska epepeja polskich żołnierzy w twórczości Juliusza Kossaka
Authors: Szeremietiew Oleg W.
Published: September 2018

In this article, the work of the outstanding Polish battle painter and the illustrator of 2-nd half XIX century J. Kossak (the founder of an art dynasty), devoted to Napoleonic Wars are considered. Many of pictures and water colors of the artist show the Polish soldiers – participants of the Epopee. In them were reflected not only the art work and research of themaster, his vision of the past, but also national – patriotic idea of revival of Poland.
Czy byliśmy w wojnie z Sowietami?!
Authors: Wysocki Wiesław Jan
Published: September 2018

At the time of the agreement with the German Third Reich on Soviet aggression on Poland on September 17, 1939, the Ambassador of the Republic of Poland in Moscow was given a diplomatic note declaring that in the face of the “break-up of the Polish state” the USSR “is defending the Belarusian and Ukrainian population” in eastern Poland. This eceptive version was “bought” by the Allies of Poland in the West who pretended that Moscow was not a co-hostile against allied Poland. They explained that they didn’t want to deepen but to overthrow the German-Soviet alliance. The highest authorities of the Republic of Poland were charged that they were not consistent and did not declare a state of war between Poland and the USSR from September 17, 1939. This was a game of slander and the author documented the will of the parties to bring such charges. In the period of the Polish People’s Republic, the myth of the so-justified Soviet intervention in 1939 was promulgated. Also, today, this issue for many politicians, historians and journalists remains not entirely clear. This text is an analysis of the formation of the basis of this myth, showing its political ground for various propaganda and proclamation of Western states, and ambiguous attitudes of Polish politicians, especially focused on the very naive and politically dependent General Sikorski, the chief of war and prime minister, with greater responsibility – than the ruling party of the Second Polish Republic – for establishing false opinions about Polish-Soviet relations in September 1939.
Come doveva comportarsi una donna e quali erano i suoi doveri? Indicazioni suggerite al pubblico femminile in alcune prediche di Gilberto di Tournai
Authors: Głusiuk Anna
Published: September 2018

The article presents the opinions of the 13th century preacher Gilbert of Tournai about the duties of girls, wives and widows. Gilbert seeing the great lack of women’s education addressed his sermons to them and indicated which behaviors were correct and which they should change or avoid. His sermons show how the women was seen, which was her  position and role in the 13th century French society.
PRÓBY PRZEDZIERANIA SIĘ DROGĄ MORSKĄ PRZEZ NIEMIECKĄ BLOKADĘ POLSKIEGO WYBRZEŻA 1 IX 2 X 1939 ROKU
Authors: Sykut Piotr
Published: September 2018

The article presents the attempts of Polish coast defenders’ to get through to neutral countries by sea during military operations in September and October 1939. These efforts were made in spite of the German blockade of Polish coast by Kriegsmarine ships and Luftwaffe planes. This subject hasn’t been widely featured yet using the reports of coast defenders kept in Polish and foreign archives. The goal of this article is the systematization of knowledge about these facts, presentation of characters of sailors, soldiers and civilians, who didn’t want to go into captivity. Some of them were going to continue their struggle in Polish Armed Forces in the West.
Assessment of Transmitted HIV-1 Drug Resistance Mutations Using Ultra- Deep Pyrosequencing in a Turkish Cohort
Authors: Sili Uluhan , Aksu Burak , Tekin Aysun , Hasdemir Ufuk , Soyletir Guner , Korten Volkan
Published: September 2018

Background:

Antiretroviral treatment (ART) reduces morbidity and mortality caused by human immunodeficiency virus (HIV) infection; however, the emergence of drug-resistant strains poses an important obstacle to treatment success. Using conventional sequencing methods to determine antiretroviral resistance, mutations present in ≥20% of quasispecies can be identified, but drug-resistant minority variants can lead to virologic failure.

Objective:

We aimed to assess transmitted drug resistance mutations (TDRMs) within minority variants using ultra-deep pyrosequencing (UDPS).

Method:

Treatment-naive adult patients were included in this observational study. Surveillance TDRMs were classified as ≥20% or at minority variant level (≥2% – <20%). Genotypic sensitivity score calculated by using all pre-treatment drug resistance mutations (PDRMs) was also evaluated.

Results:

Thirty-six patients were analyzed. Any TDRM at ≥20% level was detected in 8.3% of the patients (n=3). This prevalence increased to 30.6% (n=11) with the inclusion of minority variants. All non-nucleoside reverse transcriptase inhibitor and protease inhibitor-related TDRMs were within minority variants. The genotypic sensitivity score of rilpivirine-based regimens was considerably diminished when minority variants were included in the PDRM analysis.

Conclusion:

UDPS was used for the first time to assess TDRM in a Turkish HIV cohort and uncovered several mutations hidden within minority variants. UDPS may be preferred to detect PDRMs for avoiding virologic failure with rilpivirine-based ART regimens.