bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH KINERJA KEUANGAN TERHADAP STRUKTUR MODAL
Authors: Bandawaty Euis , Nugraha Nugraha , Disman Disman , Sari Maya
Published: March 2024

Capital structure is an important aspect of the development of a company; insufficient capital makes it difficult for the company to develop business activities. Capital structure is also closely related to various aspects, such as investors. This condition makes the capital structure position an important part of the company's ability to carry out company activities. The capital structure that becomes the focus of managers and investors in various previous studies is caused by various factors, such as profitability, corporate tax, and corporate liquidity. The purpose of this study is to examine the effect of financial performance on capital structure. This research uses a quantitative approach that focuses on INAF companies during 2010–2020. The data analysis method used in this research is an analysis by comparing emerging market countries with developed market countries. The result shows that the lower the profitability, the higher the capital structure, which indicates that the company increases the capital structure when the profitability decreases. Corporate tax in this study indicates that with a higher corporate tax, the capital structure also increases. This indicates that a high tax encourages the company to increase its capital structure. Liquidity in the research shows no influence, so liquid and not-liquid companies are not factors that cause changes in capital structure.
THE EFFECT OF THE NUMBER OF TOURISM ATTRACTIONS AND RESTAURANTS ON LOCAL OWN-SOURCE REVENUE IN THE REGENCY/CITY OF LAMPUNG PROVINCE
Authors: Aminda Renea Shinta , Rahmawati Evi
Published: March 2024

Local own-source revenue has an important role in supporting local government funding sources to finance all regional operational and development needs, and other forms of public services. Therefore, to increase local revenue, the government must optimize which sectors can contribute. One of the efforts to increase local own source revenue is by optimizing the potential in the tourism sector. The tourism sector will contribute to local own source revenue through tourist attraction fees and restaurant taxes. This research was conducted to determine the effect of the number of tourist attractions and restaurants on Local Own –Source Revenue in the Regency/City of Lampung Province in 2011-2020. The data in this study is secondary data obtained through the Central Bureau Statistics and the Lampung Provincial Tourism Office. This study uses panel data regression analysis with the program used, namely Stata14, and uses hypothesis testing on a significance basis of 0.05 or 5%. The results of this study indicate that (1) tourist attractions do not have a significant influence on Regional Original Income in Lampung Province (2) restaurants have a significant influence on Local Own-Source Revenue in the Regency/City of Lampung Province. In addition, from this study, it can be seen that the variable number of tourist visits and restaurants has an effect on Local source revenue. The data in this study is secondary data obtained through the Central Bureau Statictic (BPS) and the Lampung Provincial Tourism Office. This research is a type of quantitative descriptive research with an analysis method using panel data regression with the program used, namely Stata 14, and uses hypothesis testing on a significance basis of 0.05 or 5%. The results of the tests conducted in this study are that there is no significant effect where when tourist attractions increase it does not result in an increase in Local Own – Source Revenue. Restaurants have a significant influence on Local Own – Source Revenue in the Regency/City of Lampung Province in 2011 and 2020. This shows that restaurants are one of the indicators of increasing Local own-source Revenue  in  the Regency/City of Lampung Province
Тема родины в тувинской и бурятской прозе 1960–1970-х годов
Authors: Имихелова Светлана Степановна , Монгуш Евгений Докурович , Синячкин Владимир Павлович
Published: March 2024

В статье осуществлен сравнительно-сопоставительный анализ тувинской и бурятской прозы 1960–1970-х годов, посвященной теме родины, родного края. Выделен образ дома и связанные с ним мотивы памяти, детства, а также образы родной природы как отражение этнокультурных ценностей и как точки соприкосновения двух литератур. Рассмотрены художественные поиски тувинских и бурятских писателей в автобиографической прозе. В решении темы родины обнаружилось как сходство в сближении специфически-бытовой и универсально-бытийной сфер, так и различия, обусловленные выбором жанровых решений и повествовательных приемов.
В тувинских автобиографических произведениях на тему родины проанализировано оригинальное соединение прозы и поэзии, которое ведет к жанровому облику лирического эпоса. В бурятской прозе исследованы повествовательные традиции исторического романа с использованием структуры текста в тексте и автобиографической книги с опорой на публицистический пафос.
Сделан вывод о стремлении тувинских и бурятских писателей поднять тему родины до высоты универсального культурного опыта, что дает возможность подчеркнуть общее и особенное в открытии новых жанровых модификаций, изменений в повествовательной структуре, в облике героя-повествователя, в его взаимоотношениях с автором и читателем.
Comparison of seven commercial RT-PCR kits with the NIV kit for the diagnosis of Covid-19
Authors: Chhabra Mala , Nirmal Kirti , Chauhan Ankit , Athotra Aditya , Kansra Stuti , Shulania Anuradha , Achra Arvind , Duggal Nandini
Published: March 2024

Objectives

Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spread across the globe in an unprecedented manner and was declared a pandemic on March 11, 2020 by the World Health Organization (WHO). This study was carried out with the aim to compare the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and agreement of the eight different RT-PCR kits for the diagnosis of COVID-19.

Material and Methods

This observational cross-sectional study was carried out in the Department of Microbiology of a tertiary care hospital in Central Delhi from July to October 2021. A total of 45 nasopharyngeal and/or oropharyngeal swabs in Viral Transport Medium (VTM) from suspected COVID-19 patients were received in the laboratory for RT-PCR. These samples were tested by eight different Indian Council of Medical Research (ICMR)-approved RT-PCR kits with different gene targets. The comparison was made with the National Institute of Virology (NIV), the Pune COVID-19 RT-PCR kit. Statistical analysis: sensitivity, specificity, PPV, and NPV were calculated for each kit and compared using the McNemar test. Agreement of different kits was evaluated using Kappa analysis.

Results

The results of the 45 samples of suspected COVID-19 cases were recorded as per the cycle threshold (Ct) provided in the kit insert. Of these, 15 samples detected both E and RdRp genes and 30 were negative for both the genes of SARS CoV-2 by NIV, the Pune COVID-19 RT-PCR kit. All kits showed 100% sensitivity and had 100% NPV when compared with the NIV kit. However, specificity, PPV, and agreement were variable as compared to the NIV kit.

Conclusion

The reporting should be carried out as per the manufacturer’s instructions. However, positive results with Ct values ≥ 36 showed variable results with different RT PCR kits and hence should be interpreted with caution.
СЕЗОННАЯ ДИНАМИКА ЗАПАСОВ ЖИВОЙ НАДЗЕМНОЙ ФИТОМАССЫ РАСТИТЕЛЬНЫХ СООБЩЕСТВ МАРАЛОВОДЧЕСКОГО ХОЗЯЙСТВА «ТУРАН» (РЕСПУБЛИКА ТЫВА)
Authors: Ананды Ш.Д. , Самбыла Ч.Н.
Published: March 2024

В июне-августе 2019-2022 гг. изучена сезонная динамика запасов живой надземной фитомассы луговых и степных растительных сообществ парковых зон ГУП Республики Тыва мараловодческого хозяйства «Туран». Определение живой надземной фитомассы в 65 ключевых участках (м2) проводились методом укосов, геоботанические описания растительных сообществ проводились по стандартной методике. Установлено, что за июнь-август живая надземная фитомасса варьирует в пределах от 96 до 3207 г/м2, в том числе 96-705 г/м2 в степных и 98-3207 г/м2 луговых сообществах. Этот показатель соответственно, в июле, в 2-5 и 2-11 раз больше, чем в июне и в августе.
БЕЛОЗУБКА МАЛАЯ (CROCIDURA SUAVEOLENS PALL., 1811) В ЭКОСИСТЕМАХ КАБАРДИНО-БАЛКАРИИ
Authors: Дзуев Р.И. , Канукова В.Н. , Хуламханова М.М. , Чепракова А.А. , Шугушева Л.Х. , Шарибова А.Х. , Арсамакова М.К.
Published: March 2024

Белозубка малая (Crocidura suaveolens Pallas, 1811), являясь аборигенным видом микромаммалия Кавказа, играет важную роль в поддержании структуры природных и антропогенных экосистем региона. Настоящее исследование, посвященное изучению относительного обилия вида в различных ландшафтно-экологических условиях Кабардино-Балкарии, позволило выявить следующее. Наибольшее относительное обилие вида характерно в околоводных интразональных ландшафтах. С продвижением в горы показатель обилия вида уменьшается. В городских условиях (г.о. Нальчик) заселяет урбанистические, индустриальные, рекреационные ландшафты. В зимний период регистрируется в жилище человека, что требует налаживания мониторинга инфицированности C. suaveolens возбудителями заболеваний опасных для человека, в том числе туляремия.
ВЛИЯНИЕ ТАРГЕТНОЙ ТЕРАПИИ ПРИ ПСОРИАЗЕ НА ИЗМЕНЕНИЕ СИМБИОНТНОЙ МИКРОБИОТЫ ГЕНИТАЛИЙ
Authors: Савчков Г.В. , Нестеров А.С. , Погольдин Н.Д. , Нестерова А.В.
Published: March 2024

Установлено, что новые генно-инженерные биологические препараты (ГИБП), являющиеся эффективным средством лечения псориаза средней и тяжелой степени, при генитальном псориазе вызывают нарушение симбионтной микробиоты данной зоны. Развивается генитальный дисбиоз, проявляющийся снижением содержания нормобиоты на фоне увеличением численности условно патогенных и патогенных видов, что может являться важным фактором развития осложнений псориаза.
КОМПЛЕКСНЫЙ ПОДХОД К ОПРЕДЕЛЕНИЮ ПАРАМЕТРОВ ПОЖАРОВЗРЫВООПАСНЫХ ЗОН ПРИ НАТЕКАНИИ ВОДОРОДА В РЕАКТОРНОМ ЗДАНИИ АЭС С ВВЭР
Authors: Лебедченко О.С.
Published: March 2024

Система контроля и удаления водорода из защитной оболочки АЭС с водно-водяными реакторами включает пассивные методы. Определение концентрации водорода в гермзоне реакторного здания и его удаление при проектных авариях производится с использованием датчиков водорода и каталитических рекомбинаторов. Вода в первом контуре реакторной установки под действием излучения подвергается радиолизу, поэтому выделение водорода происходит при штатной работе атомной станции. В статье представлены модельные задачи и их аналитические решения в случаях натекания водорода в реакторное здание. Представлена методика расчета концентрационных полей водорода в зданиях АЭС с ВВЭР. Приведена математическая зонная модель, позволяющая выявить не предусмотренное технологическим процессом образование взрывопожароопасной водородно-воздушной смеси и определить необходимую степень чувствительности приборов контроля концентрации водорода в реакторном здании АЭС, а также дать рекомендации по их оптимальному расположению.
Accessing a Diverse Set of Functional Red-Light Photoswitches by Selective Copper-Catalyzed Indigo N-Arylation
Authors: Jaiswal Amit K. , Saha Priya , Jiang Julong , Suzuki Kimichi , Jasny Anna , Schmidt Bernd M. , Maeda Satoshi , Hecht Stefan , Huang Chung-Yang (Dennis)
Published: March 2024

The ability to correlate the structure of a molecule to its properties is the key to a rational and accelerated design of new functional compounds and materials. Taking photoswitches as an example, the thermal stability of meta-stable state is a crucial property that dictates their application in molecular systems. Indigos have recently emerged as an attractive motif for designing photoswitchable molecules due to their red-light addressability, which can be advantageous in biomedical and material applications. The absence of comprehensive synthetic techniques and a thorough understanding of the impact of structural factors on the photochemical and thermal properties of this widely available dye hinders its broad application. Herein, we report an efficient copper-catalyzed indigo N-arylation that enables the installation of a wide variety of aryl moieties carrying useful functional groups. The exclusive selectivity for mono-arylation likely originates from a bimetallic cooperative mechanism through a binuclear copper-indigo intermediate. Functional N-aryl-N′-alkylindigos were prepared and shown to photoisomerize efficiently under red light. Moreover, this design allows for the modulation of thermal half-lives through N-aryl substituents, while the N′-alkyl groups enable the independent attach-ment of functional moieties without affecting the photochromic properties. Strong correlation between the structure of N-aryl moiety and the thermal stability of the photogenerated Z-isomers was achieved by multivariate linear regression models obtained through a straightforward data-science workflow. This work thus builds an avenue leading to versatile red-light photoswitches and a general method for structure-property correlation that is expected to be broadly applicable to the design of photoresponsive molecules.
Self-Replicating DNA-Based Nanoassemblies
Authors: Akter Nahida , Alladin-Mustan B. Safeenaz , Liu Yuning , An Jisu , Gibbs Julianne M.
Published: March 2024

The properties of DNA that make it an effective genetic material also allow it to be ideal for programmed self-assembly. Accordingly, DNA-programmed assembly has been utilized to construct responsive DNA origami and wireframe nanoassemblies, yet the replication of these hybrid nanomaterials remains a challenge. Here we report a strategy for replicating DNA wireframe nanoassemblies using the isothermal ligase chain reaction lesion-induced DNA amplification (LIDA). In this first generation, we designed a triangle wireframe structure that can be formed in one step by ring-closing its linear analog. Introducing a small amount of the wireframe triangle to an excess of the linear analog and complementary Fragments, one of which contained a destabilizing abasic lesion, led to rapid sigmoidal self-replication of the wireframe triangle via cross-catalysis. Using the same cross-catalytic strategy we also demonstrated rapid self-replication of a hybrid wireframe triangle containing synthetic vertices as well as the self-replication of circular DNA. This work reveals the suitability of isothermal ligase chain reactions such as LIDA to self-replicate complex DNA architectures, opening the door to incorporating self-replication, a hallmark of life, into biomimetic DNA nanotechnology.
Projected atomic orbitals as optimal virtual space for excited state projection-based embedding calculations
Authors: Szirmai Ádám B. , Hégely Bence , Tajti Attila , Kállay Mihály , Szalay Péter G.
Published: March 2024

The projected atomic orbitals (PAO) technique is presented for the construction of virtual orbital spaces in projection-based embedding (PbE) applications. The proposed straightforward procedure produces a set of virtual orbitals, which is used in the final, high-level calculation of the embedded active subsystem. The PAO scheme is demonstrated on intermolecular potentials of bimolecular complexes, in ground and excited states, including Rydberg excitations. The results show the outstanding performance of the PbE method when used with PAO virtual orbitals compared to those produced using common orbital localization techniques. The good agreement of the resulting PbE potential curves with those from high-level \ai dimer calculations, also in diffuse basis sets, confirms that the PAO technique can be suggested for future applications using top-down embedding methods.
A Quest for Parsimonious Topology of Polyhedral Cavities in Metal–Organic Frameworks
Authors: Lee Soochan , Lee Sungmin , Kwak Yuna , Yousaf Masood , Moon Hoi Ri , Cho Sung June , Park Noejung , Choe Wonyoung
Published: March 2024

A new topology previously unknown in metal–organic frameworks (MOFs) provides an important clue to uncovering a new series of polyhedral MOFs. We report a novel MOF crystallized in a parsimonious mep topology based on Frank–Kasper (FK) polyhedra. The distribution of angles in a tetrahedral arrangement (T-O-T) is crucial for the formation of FK polyhedra in mep topology. This finding led us to investigate the T-O-T angle distribution in related zeolites and zeolitic imidazolate frameworks (ZIFs). Unlike zeolites, it is extremely difficult to achieve high T-O-T angles in ZIFs, which prevents the formation of some FK topologies. Density functional theory (DFT) total energy calculations support a correlation between T-O-T angles and the feasibility of new tetrahedron-based FK frameworks. This result may lead to innovative ways of accessing new cellular topologies by simple chemical tweaking of T-O-T angles.
Photoelectron Imaging Signature for Selective Formation of Icosahedral Anionic Silver Cages Encapsulating Group 5 Elements: M@Ag12− (M = V, Nb, and Ta)
Authors: Suzuki Yuta , Matsumoto Kazuaki , Nomi Rin , Arakawa Masashi , Horio Takuya , Terasaki Akira
Published: March 2024

An assembly of thirteen atoms is expected to be a distinctive nanocluster, as they can form highly symmetric architectures like those belonging to D3h, Oh, D5h, and Ih point groups. Among them, icosahedra are the best known as the iconic structures in the finite size regime. Here, using photoelectron imaging spectroscopy in combination with density functional theory (DFT) calculations, we present a simple yet convincing experimental signature for selective formation of icosahedral cages of anionic silver clusters encapsulating a dopant atom of group 5 elements: M@Ag12− (M = V, Nb, and Ta). Their photoelectron images obtained at 4 eV closely resemble one another, indicating that the doped clusters are all in valence iso-electronic systems. Most strikingly, only a single ring is observed, which is assignable to photodetachment signals from a five-fold degenerate superatomic 1D electronic shell in the 1S21P61D10 configuration of valence electrons. The perfect degeneracy of the 1D orbital represents an unambiguous fingerprint of an icosahedral symmetry, which would otherwise be lifted in all the other possible structural isomers. The experimental results are fully supported by DFT calculations, which reveal that icosahedral geometries with the spin multiplicity of singlet are the most stable forms for M@Ag12− (M = V, Nb, and Ta) and that D5h, Oh, and D3h structures are not found even in metastable states.
Exploring the Reactivity of Rigid 1-Azadienes Derived from Methylene γ-Lactams. Applications to the Stereoselective Synthesis of γ-Spirolactams.
Authors: López-Francés Adrián , Serna-Burgos Zuriñe , del Corte Xabier , de los Santos Jesús M. , de Cózar Abel , Vicario Javier
Published: March 2024

A study on the reactivity of rigid 1-azadienes derived from methylene γ-lactams is reported. Through the functionalization of 1-amino α,β-unsaturated γ-lactam derivatives, easily available from a multicomponent reaction of amines, aldehydes and pyruvates it is possible to in situ generate rigid 1-azadienes locked by a γ-lactam core. The 4π-system of those rigid 1-azadienes can behave as both diene and dienophile species, through a spontaneous cyclodimerization reaction, or exclusively as dienes or dienophiles if they are trapped with imines or cyclopentadiene, respectively. The use of chiral rigid 1-azadienes as dienophiles in the cycloaddition reaction with cyclopentadiene leads to the formation of γ-spirolactams bearing four stereogenic centers in a highly stereospecific manner, reporting the first example of the use of methylene-γ-lactams in the synthesis of spirocycles.
Prediction of Inhibitory Activity Against the MATE1 Transporter via Combined Fingerprint- and Physics-Based Machine Learning Models
Authors: Handa Koichi , Sasaki Shunta , Asano Satoshi , Kageyama Michiharu , Iijima Takeshi , Bender Andreas
Published: March 2024

Renal secretion plays an important role in drug excretion from the kidney. Two major transporters known to be highly involved in renal secretion are MATE1/2-K and OCT2, the former of which is highly related to drug-drug interactions. Among published in silico models for MATE inhibitors, a previous model obtained a ROC-AUC value of 0.78 using high throughput percentage inhibition data [J Med Chem. 2013;56(3): 781–795] which we aimed to improve upon here using a combined fingerprint and physics-based approach. To this end, we collected 225 publicly available compounds with pIC50 values against MATE1. Subsequently, on the one hand we performed a physics-based approach using an Alpha-Fold protein structure, from which we obtained MM-GB/SA scores for those compounds. On the other hand, we built Random Forest (RF) and Message Passing Neural Network (MPNN) models using Extended-Connectivity Fingerprints with radius 4 (ECFP4) and chemical structures as graphs, respectively, which also included MM-GB/SA scores as input variables. In a five-fold cross-validation with a separate test set we found that the best predictivity for the hold-out test was observed in the RF model (including ECFP4 and MM-GB/SA data) with an ROC-AUC of 0.833±0.036; while that of the MM-GB/SA regression model was 0.742. However, the MM-GB/SA model was able to extrapolate to novel chemical space better. Additionally, via Structural Interaction Fingerprint analysis, we identified interacting residues with inhibitor as identical for those with non-inhibitors, including substrates, such as Gln49, Trp274, Tyr277, Tyr299, Ile303, Tyr306. The similar binding modes are consistent with the observed similar IC50 values inhibitor when using different substrates experimentally, and practically this can release the experimental scientists from bothering of selecting substrates for MATE1. Hence, we were able to build a highly predictive classification models for MATE1 inhibitory activity with both ECFP4 and MM-GB/SA score as input features, which is fit-for-purpose for use in the drug discovery process.
What leads to direct epoxidation? An exhaustive DFT investigation of electrophilic oxygen mediated epoxidation of ethylene on Ag(100)
Authors: Nair Aathira , Joshi Kavita
Published: March 2024

Extensive research has contributed to a better understanding of the commercially important epoxidation reaction. Selectivity, a crucial aspect of this reaction, has re- ceived significant attention in both experimental and theoretical investigations. How- ever, a consensus regarding the role of electrophilic oxygen in epoxidation is yet to be reached. The present study is a theoretical examination of the prerequisites necessary for direct epoxidation to occur on the Ag(100) surface, at varied monolayer concentra- tions. Additionally, the study investigates the characteristics of various oxygen species interacting with ethylene to promote the direct epoxidation pathway. Based on the effective charges and projected density of states (pDOS) analysis, three oxygen vari- ants were identified on the Ag(100) surface: atomic oxygen, dissociatively adsorbed molecular oxygen, and O3 . The investigation reveals that all oxygen species, despite their physical and electronic differences, are electrophilic and undergo direct epoxida- tion. This work provides insights into the complex nature of epoxidation reaction and discusses electronic factors influencing the selective oxidation route on different Ag-O complexes.
Improved Mechanical Properties of Graphene/Carbon Fibre Composites via Silanization
Authors: Yao Xudan , Hui Jason , Kinloch Ian , Bissett Mark
Published: March 2024

Despite their excellent mechanical performance, carbon fibre reinforced polymer (CFRP) composites are limited by the interfacial properties due to the inherent nature of laminated structures. One way to modify the interface is by the inclusion of nanomaterials on the surface of carbon fibres. Here, we use electrochemical exfoliation to produce graphene (EEG) flakes which have hydroxyl and epoxy functional groups on their surface. To further improve the interfacial bonding between the flakes and the epoxy matrix, silanization was carried out on the graphene, with 3-aminopropyl triethoxysilane (APTES) which could react with both oxygen and amino groups, and then EEA flakes achieved. Combing SEM and AFM, lateral size and thickness of both flakes were characterized, which showed comparable values, and thus removed the effect of aspect ratio during the comparison. Both EEG and EEA flakes were dispersed in ethanol and sprayed coated onto carbon fibres, followed by vacuum assisted resin infusion to make hybrid composites. Testing of their mechanical properties showed that EEG flakes tend to act as points of stress concentration which accelerated the delamination; while the EEA flakes improved interfacial properties owing to the covalent bonding. As a result, with only 0.5 wt.% EEA flakes spray coated onto the carbon fibres, the tensile and flexural strength of graphene/carbon fibre composites improved by 17.6% and 5.4% respectively.
Multi-Scale Modeling of Physical Properties of Nanoporous Frameworks: Predicting Mechanical, Thermal and Adsorption Behavior
Authors: Hardiagon Arthur , Coudert François-Xavier
Published: March 2024

Nanoporous frameworks are a large and diverse family of materials, with a key role in various industrial processes and applications such as energy production and conversion, fluid separation, gas storage, water harvesting, and many more. The performance and suitability of nanoporous materials for each specific application are directly related to both its physical and chemical properties, and their determination is crucial for process engineering and optimization of performances. In this Account, we focus on some recent developments in the multi-scale modeling of physical properties of nanoporous frameworks, highlighting the latest advances in three specific areas: mechanical properties, thermal properties, and adsorption. For the study of the mechanical behavior of nanoporous materials, the last few years have seen a rapid acceleration of research. For example, computational resources have been pooled to created public large-scale databases of elastic constants: those can serve as a basis for data-based discovery of materials with targeted properties, as well as the training of machine learning predictor models. The large-scale prediction of thermal behavior, in comparison, is not yet routinely performed at such large scale. Tentative databases have been assembled at the DFT level on specific families of materials, like zeolites, but prediction at larger scale currently requires the use of transferable, classical force fields, whose accuracy can be limited. Finally, adsorption is naturally one of the most studied physical properties of nanoporous frameworks, as fluid separation or storage is often the primary target for these materials. We highlight the recent achievements and open challenges for adsorption prediction at large scale, focusing in particular on the accuracy of computational models and the reliability of comparisons with experimental data available. We detail some recent methodological improvements in the prediction of adsorption-related properties, including thermodynamic quantities and transport properties. Finally, we stress the importance for data-based methods of addressing all sources of uncertainty. The Account concludes with some perspectives about the latest developments and open questions in data-based approaches, and the integration of computational and experimental data together in the materials discovery loop.
Patriarchy and Oppression in Sylvia Plath’s Lady Lazarus
Authors: Karo Hasan H.
Published: March 2024

This paper discusses Sylvia Plath’s feelings towards her patriarchal society. In her poem, Lady Lazarus, she expresses her contempt for the mistreatment she receives from the close male members of her family, her father, and husband. Through the poetic lines in the poem, she illustrates the world that women live within a patriarchal society. This paper justifies her hatred of men that Plath conveys in her poem. Her poetic lines in Lady Lazarus are analyzed to show her inner feelings. The paper also explains Plath’s attitude against this oppression that she suffers from. It explains how Plath employs  an example of oppression to blame patriarchy for their actions.
Analisis Pengaruh Brand Ambassador dan Brand Awareness Terhadap Keputusan Pembelian Sabun Pemutih Lux Dengan Variabel Minat Beli Sebagai Variabel Intervening
Authors: Habibi Mahsyar Januar , Hadi Gunawan Wely
Published: March 2024

Penelitian ini meneliti pengaruh brand ambassador dan brand awareness terhadap keputusan pembelian sabun pemutih Lux, dengan minat beli sebagai variabel intervening.  Metode penelitian yang digunakan adalah deskriptif kuantitatif dengan menggunakan metode survei kepada 180 sampel. Variabel penelitian meliputi brand ambassador, brand awareness, minat beli, dan keputusan pembelian, dengan masing-masing variabel memiliki indikator penelitian yang spesifik. Selain itu, penelitian ini juga menggunakan analisis model kausalitas dan teknik analisis Structural Equation Modeling (SEM) yang dioperasikan melalui program AMOS untuk menguji hipotesis yang diajukan. Proses permodelan SEM melibatkan langkah-langkah seperti pengembangan teori berdasarkan model, pembentukan diagram alur dari hubungan kausal, pengubahan alur diagram ke dalam persamaan struktural, dan penyusunan model pengukuran. Hasil penelitian menunjukkan bahwa brand ambassador secara signifikan meningkatkan minat beli dan keputusan pembelian konsumen. Sementara itu, brand awareness berdampak positif terhadap minat beli tetapi tidak selalu menghasilkan keputusan pembelian. Riset ini mengindikasikan bahwa minat beli merupakan mediator kunci antara pengaruh brand awareness dan keputusan pembelian konsumen. Temuan ini memberikan wawasan strategis untuk inisiatif pemasaran, menekankan pentingnya menyelaraskan brand ambassador dengan citra dan karakteristik produk serta memperkuat brand awareness untuk meningkatkan minat dan komitmen pembelian konsumen.
Strukur Modal dan Kepemilikan Terhadap Kinerja Keuangan Industri Manufakur Sektor Konsumsi yang Terdaftar di Bursa Efek Indonesia (BEI) 2017 – 2020
Authors: Purwanti Tri , Rochyawati Qudrat Mulya Fety Rochyawati Qudrat Mulya
Published: March 2024

Penelitian ini bertujuan untuk mengkaji pengaruh struktur modal dan struktur kepemilikan terhadap kinerja keuangan. Penelitian ini menggunakam pengukuran untuk mengukur struktur modal yaitu Debt to Assets Ratio (DAR) serta Debt to Equity Ratio (DER), Struktur Kepemilikan Manajerial, Struktur Kepemilikan Institusional, untuk melihat pengaruh terhadap kinerja keuangan yang diukur dengan menggunakan Return on Assets (ROA) dan Return on Equity (ROE). Populasi dalam penelitian ini adalah perusahaan manufaktur sektor konsumsi yang terdaftar di Bursa Efek Indonesia (BEI) pada periode 2017 – 2020. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling dengan sampel sebanyak 24 perusahaan manufaktur sektor konsumsi bahan makanan dan minuman yang terdafftar di Bursa Efek Indonesia (BEI) pada periode 2017 – 2020. Teknik analisis yang digunakan adalah teknik analisis regresi linier berganda, dengan mendapatkan hasil penelitian struktur modal (DAR) memiliki pengaruh negatif dan signifikan terhadap kinerja keuangan (ROA dan ROE), sedangkan struktur modal (DER) memiliki pengaruh positif dan signifikan terhadap kinerja keuangan (ROA dan ROE). Namun untuk struktur kepemilikan manajerial tidak berpengaruh terhadap kinerja keuangan perusahaan. Struktur kepemilikan institusional memiliki pengaruh positif dan signifikan terhadap kinerja keuangan (ROA dan ROE) perusahaan yang manufaktur sektor konsumsi bahan makanan dan minuman yang terdafatr di BEI tahun 2017 – 2020.
Hurdles in investigating UVB damage in the putative ancient asexual Darwinula stevensoni (Ostracoda, Crustacea)
Authors: Van den Broecke Lynn , Vanfleteren Jacques , Martens Koen , Schön Isa
Published: March 2024

Ostracoda or mussel-shrimps are small, bivalved Crustacea. Because of their excellent fossil record and their broad variety of reproductive modes, ostracods are of great interest as a model group in ecological and evolutionary research. Here, we investigated damage and repair from one of the most important biological mutagens, namely UVB radiation, in the putative ancient asexual ostracod Darwinula stevensoni from Belgium. We applied three different methods: the Polymerase Inhibition (PI) assay, Enzyme-Linked Immuno Sorbent Assay (ELISA) and dot blot. All three techniques were unsuccessful in quantifying UVB damage in D. stevensoni. Previous experiments have revealed that the valves of D. stevensoni provide an average UVB protection of approximate 60%. Thus, UVB damage could be too little to make quantitative experiments work. Additionally, variation between individual ostracods due to season and age most likely contributed further to the failure of the three used experimental approaches to quantify damage. In a second experiment, we investigated the influence of temperature on survival of D. stevensoni during UVB exposure. The estimated relative lethal UVB dose at 4°C was with 50 kJ/m2, significantly lower than at room temperature, with 130 kJ/m2. This could either indicate lack of adaptation to low temperatures and/or the presence of metabolic processes active at room temperature protecting against UVB damage in D. stevensoni. The latter possibility could also explain why the estimated relative lethal UVB dose of D. stevensoni is similar to that of other non-marine ostracods where valves provide around 80% protection, despite the valves of D. stevensoni providing less protection. If such metabolic processes can repair UVB damage quickly, this may provide an alternative explanation why we could not quantify UVB damage in D. stevensoni.
The Effect of Situational Simulation Education Teaching Mode on Clinical Obstetrics and Gynecology Specialty Teaching: A Comparative Study
Authors: Liu Feifei , Zhang Lili
Published: March 2024

Objective: To explore the effectiveness of applying the situational simulation education teaching mode in clinical gynecology and obstetrics specialty education. Methods: Seventy personnel specializing in clinical gynecology and obstetrics at Shaanxi Provincial People’s Hospital between June and October 2023 were selected and randomly divided into a control group and a research group, with 35 personnel in each. The control group underwent traditional teaching methods, while the research group received instruction through the situational simulation education teaching mode. The study then compared the satisfaction levels of the two groups regarding the teaching methods, as well as their scores on theoretical and practical examinations. Results: Following the teaching sessions, the research group exhibited a teaching satisfaction rate of 94.29%, significantly higher than that of the control group (P < 0.05). Moreover, when comparing the scores of theoretical and practical examinations, the research group outperformed the control group, with statistical significance (P < 0.05). Conclusion: The implementation of situational simulation education teaching mode in clinical gynecology and obstetrics significantly enhances the satisfaction levels of professional personnel and improves their theoretical knowledge and clinical operational skills.
The Evaluation of Risk-Based Resource Allocation Alternatives Based on Fuzzy Information Axiom
Authors: Yu Jie , Wang Yuliang
Published: March 2024

This paper presents an analysis of the challenges in risk-based resource allocation in engineering projects. Sub-sequently, an alternative resource allocation evaluation method based on language information and information axioms is proposed. Firstly, the evaluation team uses language information to give the evaluation information of the alternatives of risk resource allocation and provides the corresponding expected information for each resource. Secondly, according to the transformation formula of language information and fuzzy numbers, the above information is transformed into the evaluation information and expected information of the alternatives of risk-based resource allocation. Thirdly, according to the transformation formula of language information and fuzzy numbers, the above information is transformed into evaluation information and expectation information of alternative risk resource allocation. Finally, according to the information amount of each risk resource and the corresponding weight, the comprehensive information amount of the expected risk-based resource allocation alternatives is determined.
Research on the Shape and Structure of Mamianqun in the Ming and Qing Dynasties
Authors: Ge Yingying , Xu Henan
Published: March 2024

Mamianqun (horse-faced skirt) is one of the most typical dress patterns of traditional Chinese costume. In the long history of mamianqun, it was the Ming and Qing dynasties that were the heyday of its development. The changes were varied, and the styles were also novel and changeable, all of which demonstrated the mature progress of traditional costume in the Ming and Qing dynasties, making it the epitome of costume during that period. Starting from mamianqun, this paper focuses on the shape and structure of mamianqun during the Ming and Qing dynasties as its research subject and explores the significance of the times behind mamianqun by analyzing its shape, structure, and modeling characteristics.
Exploration of the Impact of Dynamic Narrative Approach on Public Exhibition Experience
Authors: Chi Siqi
Published: March 2024

In today’s exhibition field, the dynamism of the narrative approach as a mainstream trend has permeated various aspects such as visual design, exhibit display, and media communication. On one hand, this is due to the development of digital media technology providing practical operational pathways; on the other hand, it is also a result of the information explosion brought about by the maturity of digital media technology, forcing exhibitions, as an important form of public cultural service, to stimulate public interest to the fullest extent in competition with other cultural products. In such a coincidental yet inevitable combination, how to effectively utilize a dynamic narrative approach within the exhibition field to provide the public with a sense of unfamiliarity in dimensions, boundaries, and situations, thereby constructing a unique perspective that enables people to perceive alienation relationships and ultimately resist the control of the technological landscape on humanity, becomes the key issue determining whether the integration between the two can be beneficial.
The Effect of Cylindrical Grip ROM Exercise Therapy on Finger Grip Muscle Strength in The Upper Extremities of Post Stroke Patients
Authors: Pratiwi Rizky Meuthia
Published: March 2024

One of the conditions in post-stroke patients is that post-stroke sensory and motor disorders occur on one side of the body, resulting in balance disorders including muscle weakness.Based on a preliminary study conducted in June 2023, it was discovered that 5 respondents who were in the Inpatient Room at Siti Hajar Hospital Sidoarjo most often experienced paralysis in the upper extremities caused by decreased muscle tone so that patients were unable to move their bodies (immobilization). extremity motor abilities through a rehabilitation program.Cylindrical Grip which is a functional hand exercise by holding a cylindrical object such as a glass, bottle, rolled tissue in the palm of the hand (Kleim & Jones, 2008 in Soloman, 2013). The benefits of this therapy are to increase the client's independence and increase muscle strength. Movement exercises can also be useful for improving muscle tone and tendon reflexes.This research used Pre-Experimental design with One Group Pretest and Posttest approach. The population was all post-stroke patients in the inpatient ward who experienced paralysis of the upper right/sinistra extremities at Siti Hajar Hospital. The results of the study proved that there was a change in the value of finger grip muscle strength before and after Cylindrical Grip ROM exercise therapy. The majority of respondents had finger grip muscle strength in the weak category, 23 respondents (76.7%) after being given therapy, different results were obtained, namely the majority of respondents had finger grip muscle strength in the weak category, 15 respondents (50.02). This number decreased after the intervention. Pre and Post data was carried out using the Paired T Test which stated that there was an effect of Cylindrical Grip Exercise Therapy on Finger Grip Muscle Strength in post-stroke patients.
Occupational Health and Safety Knowledge correlated with The Use of PPE among Home Industry Furniture Workers in the Production Process
Authors: Aini Fatimah Nur , Sofiana Hepfi , Purwandari Henny , Nurhayati Risa
Published: March 2024

Work accident is an unexpected event that can cause loss and damage to both physical, and property and cause death. One way to prevent work accidents is to increase understanding related to occupational health and safety so that workers have the behavior of using Personal Protective Equipment (PPE) in accordance with the need to protect themselves in order to avoid work accidents. The aim of this study was to determine the correlation between knowledge about occupational health and safety and the use of Personal Protective Equipment (PPE) for furniture home industry workers in the production process in Balongrejo Village, Berbek District, Nganjuk Regency. The design of the study used correlational with a cross-sectional approach with a total of 42 respondents which selected by the Proportional Random Sampling technique. The independent variable in this study was knowledge of occupational health and safety and the dependent variable was the use of personal protective equipment (PPE). The results of the Spearman rank test showed that there was a correlation between Occupational Health and Safety Knowledge and the use of PPE for Home Furniture Industry workers in the production process in Balongrejo Village, Berbek District, Nganjuk Regency with strong correlation strength. The knowledge of workers with the behavior of using PPE is directly proportional so that the better the knowledge possessed, the better the behavior reflected, therefore it is important for nurses as educators to provide education to workers regarding the use of personal protective equipment
The Incident Prevalence of 4T High Risk Pregnant Women
Authors: Sari Dwi Linda , Mulyani Endah
Published: March 2024

Pregnancy is a physiological condition, but pregnancy can also become pathological when accompanied by high-risk conditions. Restful (high risk) pregnancies are found in pregnant women who are too old, too young, too many and too close (4T). The aim of this research was to determine the prevalence of 4T high risk pregnant women in Gresik Regency. The type of research used quantitative descriptive with a survey research design. The population in this study was all 6,929 pregnant women in Gresik Regency. The results of this study showed that the highest incidence of 4T in pregnant women in Gresik Regency was at ages over 35 years, amounting to 22.7%, which occurred in Gresik District. Health workers are expected to pay more attention to the problems they face, to prevent problems that can increase maternal mortality.
Patterns and errors of word production in aphasic contexts
Authors: Darie Eliza
Published: March 2024

This article is part of the paper „Patterns and errors of word production in aphasic contexts”. To begin with, generalities about aphasia and a cognitive neuropsychology model of spoken word production are presented, which addresses four stages involved in word retrieval: semantic system, phonological output lexicon, phonological set, and articulatory programming, and finally speech. Also, as a theoretical aspect, the three types of word utterance errors are presented: the imaginability, frequency, and length effects. The theoretical aspects are then exemplified in a case study. The aim of the research was to identify from a neurocognitive point of view in which domain the disorder is located, and which pattern of word production errors can be identified, in order to intervene specifically in language recovery, proposing an intervention plan. Among the conclusions, it can be mentioned that although aphasic symptomatology is well known, the approach from the proposed perspective created specific opportunities for recovery.
Particularities of language and communication in ASD
Authors: DÂRJAN Ioana , AL GHAZI Loredana , PREDESCU Mihai
Published: March 2024

Autism spectrum disorders (AST) are a complex and puzzling cluster of disorders in which social isolation, communication difficulties, and the presence of peculiar and/or repetitive behaviors, in various degrees, are the main characteristics. These characteristics are interlinked and share similar brain and cognitive functioning specificity. This paper focuses on communication and language disorders, their particularities in persons with AST, and their impact on differential diagnostic and specific interventions. Efficient therapeutic strategies and techniques for persons with ASD should address these strong correlations and overlaps between the specific social behavior development and the particularities of using language and communication in an ecological paradigm.
Psychological aspects of school interventions in oral and written language disorders
Authors: CĂLUGĂR Alexandra , DEZMIREAN Mara , BUZGAR Ramona , ROMAN Ioana , FĂRĂGĂU Mirela , CÂMPAN Adela
Published: March 2024

Language disorder is one of the most common childhood problems. The results of epidemiology studies are estimating that 1 in 12 preschoolers has a language disorder. The consequences of unresolved speech and language problems are significant and lead over time to behavioral disorders, mental health problems, reading difficulties, and school failure, including truancy and school dropout. Hence, we consider imperative raising awareness of this issue in the educational environment. Several studies reported an increased prevalence of social and emotional problems among children with written or spoken language disorders. Furthermore, a large body of research has demonstrated positive effects of school interventions in developing resilience strategies among children with language disorders. Accordingly, based on the results of previously conducted research of language disorders, this article presents a brief review of frequently associated social, emotional, and behavioral problems and reviews particular aspects of school interventions, which may contribute to students’ socio-emotional resilience.
Implementation in Handling Ex-Lepros Communities by The Social Service of Makassar City
Authors: Ilmi Rizky Yulia , Ibrahim Muh. Akmal , Lambali Suryadi
Published: March 2024

This research aims to find out how the implementation of the development ex-leprosy Community by the social services of Makassar city. Starts from standards and targets of resource policies, inter-organizational communication, characteristics of implementing agents and strengthening activities in economic, social and political conditions. The research method used in this study is to use a qualitative descriptive method, namely the data obtained will be analyzed and then poured into a series of words, this technique aims to systematically describe the facts and data obtained. The results of this study indicate that there are still obstacles in the implementation of handling of the excluded community based on Makassar Mayor Regulation No. 89 Years 2016 carried out by the social services of the city of Makassar. problems related to work programs, provision of skills training and basic food assistance to the community are not implemented actively and meet the needs of the ex-leprosy community in the city of Makassar.