bluuebunny/crossref_metadata_2025 huggingface dataset:
A Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Confers Full Protection against Rift Valley Fever Challenge in Sheep
Authors: Faburay Bonto , Wilson William C. , Gaudreault Natasha N. , Davis A. Sally , Shivanna Vinay , Bawa Bhupinder , Sunwoo Sun Young , Ma Wenjun , Drolet Barbara S. , Morozov Igor , McVey D. Scott , Richt Juergen A.
Published: June 2016

Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen causing disease outbreaks in Africa and the Arabian Peninsula. The virus has great potential for transboundary spread due to the presence of competent vectors in non-endemic areas. There is currently no fully licensed vaccine suitable for use in livestock or humans outside endemic areas. Here we report the evaluation of the efficacy of a recombinant subunit vaccine based on the RVFV Gn and Gc glycoproteins. In a previous study, the vaccine elicited strong virus neutralizing antibody responses in sheep and was DIVA (differentiating naturallyinfected fromvaccinatedanimals) compatible. In the current efficacy study, a group of sheep (n = 5) was vaccinated subcutaneously with the glycoprotein-based subunit vaccine candidate and then subjected to heterologous challenge with the virulent Kenya-128B-15 RVFV strain. The vaccine elicited high virus neutralizing antibody titers and conferred complete protection in all vaccinated sheep, as evidenced by prevention of viremia, fever and absence of RVFV-associated histopathological lesions. We conclude that the subunit vaccine platform represents a promising strategy for the prevention and control of RVFV infections in susceptible hosts.
Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome
Authors: Prokhorova Irina V. , Akulich Kseniya A. , Makeeva Desislava S. , Osterman Ilya A. , Skvortsov Dmitry A. , Sergiev Petr V. , Dontsova Olga A. , Yusupova Gulnara , Yusupov Marat M. , Dmitriev Sergey E.
Published: June 2016

Amicoumacin A is an antibiotic that was recently shown to target bacterial ribosomes. It affects translocation and provides an additional contact interface between the ribosomal RNA and mRNA. The binding site of amicoumacin A is formed by universally conserved nucleotides of rRNA. In this work, we showed that amicoumacin A inhibits translation in yeast and mammalian systems by affecting translation elongation. We determined the structure of the amicoumacin A complex with yeast ribosomes at a resolution of 3.1  Å. Toxicity measurement demonstrated that human cancer cell lines are more susceptible to the inhibition by this compound as compared to non-cancerous ones. This might be used as a starting point to develop amicoumacin A derivatives with clinical value.
Strain-assisted magnetization reversal in Co/Ni multilayers with perpendicular magnetic anisotropy
Authors: Gopman D. B. , Dennis C. L. , Chen P. J. , Iunin Y. L. , Finkel P. , Staruch M. , Shull R. D.
Published: June 2016

Multifunctional materials composed of ultrathin magnetic films with perpendicular magnetic anisotropy combined with ferroelectric substrates represent a new approach toward low power, fast, high density spintronics. Here we demonstrate Co/Ni multilayered films with tunable saturation magnetization and perpendicular anisotropy grown directly on ferroelectric PZT [Pb(Zr0.52Ti0.48)O3] substrate plates. Electric fields up to ±2 MV/m expand the PZT by 0.1% and generate at least 0.02% in-plane compression in the Co/Ni multilayered film. Modifying the strain with a voltage can reduce the coercive field by over 30%. We also demonstrate that alternating in-plane tensile and compressive strains (less than 0.01%) can be used to propagate magnetic domain walls. This ability to manipulate high anisotropy magnetic thin films could prove useful for lowering the switching energy for magnetic elements in future voltage-controlled spintronic devices.
Differential integrative omic analysis for mechanism insights and biomarker discovery of abnormal Savda syndrome and its unique Munziq prescription
Authors: Guo Xia , Bakri Iskandar , Abudula Abulizi , Arken Kalbinur , Mijit Mahmut , Mamtimin Batur , Upur Halmurat
Published: June 2016

Research has shown that many cancers have acommon pathophysiological origin and often present with similar symptoms. In terms of Traditional Uighur Medicine (TUM) Hilit (body fluid) theory, abnormal Savda syndrome (ASS) formed by abnormal Hilit is the common phenotype of complex diseases and in particular tumours. Abnormal Savda Munziq (ASMq), one representative of TUM, has been effective in the treatment of cancer since ancient times. Despite the physiopathology of ASS, the relationship between causative factors and the molecular mechanism of ASMq are not fully understood. The current study expanded upon earlier work by integrating traditional diagnostic approaches with others utilizing systems biology technology for the analysis of proteomic (iTRAQ) and metabolomic (1H-NMR) profiles of Uighur Medicine target organ lesion (liver) tumours. The candidate proteins were analyzed by enrichment analysis of the biological process and biomarker filters. Subsequently, 3Omics web-based tools were used to determine the relationships between proteins and appropriate metabolites. ELISA assay and IHC methods were used to verify the proteomic result; the protein von Willebrand factor (vWF) may be the “therapeutic window” of ASMq and biomarkers of ASS. This study is likely to be of great significance for the standardization and modernization of TUM.
High stability of electro-transport and magnetism against the A-site cation disorder in SrRuO3
Authors: Wang Y. L. , Liu M. F. , Liu R. , Xie Y. L. , Li X. , Yan Z. B. , Liu J.-M.
Published: June 2016

It is known that the electro-transport and magnetism of perovskite alkaline-earth ruthenate oxides are sensitive to the lattice distortion associated with the A-site cation size. Orthorhombic CaRuO3 and cubic BaRuO3 exhibit distinctly different electro-transport and magnetic properties from orthorhombic SrRuO3. It has been suggested that SrRuO3 can be robust against some intrinsic/external perturbations but fragile against some others in terms of electro-transport and magnetism and it is our motivation to explore such stability against the local site cation disorder. In this work, we prepare a set of SrRuO3-based samples with identical averaged A-site size but different A-site cation disorder (size mismatch) by Ca and Ba co-substitution of Sr. It is revealed that the electro-transport and magnetism of SrRuO3 demonstrate relatively high stability against this A-site cation disorder, characterized by the relatively invariable electrical and magnetic properties in comparison with those of SrRuO3 itself. A simple electro-transport network model is proposed to explain quantitatively the measured behaviors. The present work suggests that SrRuO3 as an itinerant electron ferromagnetic metal possesses relatively high robustness against local lattice distortion and cation occupation disorder.
A liposomal Gd contrast agent does not cross the mouse placental barrier
Authors: Shetty Anil N. , Pautler Robia , Ghaghada Ketan , Rendon David , Gao Haijun , Starosolski Zbigniew , Bhavane Rohan , Patel Chandreshkumar , Annapragada Ananth , Yallampalli Chandrasekhar , Lee Wesley
Published: June 2016

The trans-placental permeability of liposomal Gadolinium (Gd) nanoparticle contrast agents was evaluated in a pregnant mouse model. Pregnant Balb/c mice at 16.5 (±1) days of gestation were imaged using a 3D Spoiled Gradient Echo method at 9.4 T using two contrast agents: a clinically approved Gd chelate, Multihance® (gadobenate dimeglumine), and a novel experimental liposomal Gd agent. A Dynamic Contrast Enhancement (DCE) protocol was used to capture the dynamics of contrast entry and distribution in the placenta, and clearance from circulation. A blinded clinical radiologist evaluated both sets of images. A reference region model was used to measure the placental flow and physiological parameters; volume transfer constant (Ktrans), efflux rate constant (Kep). The Gd content of excised placentae and fetuses was measured, using inductively coupled plasma mass spectrometry (ICP-MS). MRI images of pregnant mice and ICP-MS analyses of placental and fetal tissue demonstrated undetectably low transplacental permeation of the liposomal Gd agent, while the clinical agent (Multihance) avidly permeated the placental barrier. Image interpretation and diagnostic quality was equivalent between the two contrast agents. Additional testing to determine both maternal and fetal safety of liposomal Gd is suggested.
Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway
Authors: Zhou Xiaoqiao , Li Xiaowen , Wang Xiliang , Jin Xiue , Shi Deshi , Wang Jun , Bi Dingren
Published: June 2016

Cecropins are peptide antibiotics used as drugs and feed additives. Cecropin B can inhibit the expression of CYP3A29, but the underlying mechanisms remain unclear. The present study was designed to determine the mechanisms responsible for the effects of cecropin B on CYP3A29 expression, focusing on the Toll-like receptors (TLRs) and NF-κB pathways. Our results indicated that the CYP3A29 expression was inhibited by cecropin B, which was regulated by pregnane X receptor (PXR) in a time- and dose-dependent manner. Cecropin B-induced NF-κB activation played a pivotal role in the suppression of CYP3A29 through disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences. NF-κB p65 directly interacted with the DNA-binding domain of PXR, suppressed its expression, and inhibited its transactivation, leading to the downregulation of the PXR-regulated CYP3A29 expression. Furthermore, cecropin B activated pig liver cells by interacting with TLRs 2 and 4, which modulated NF-κB-mediated signaling pathways. In conclusion, cecropin B inhibited the expression of CYP3A29 in a TLR/NF-κB/PXR-dependent manner, which should be considered in future development of cecropins and other antimicrobial peptides.
Hydrothermal growth of VO2 nanoplate thermochromic films on glass with high visible transmittance
Authors: Zhang Jiasong , Li Jingbo , Chen Pengwan , Rehman Fida , Jiang Yijie , Cao Maosheng , Zhao Yongjie , Jin Haibo
Published: June 2016

The preparation of thermochromic vanadium dioxide (VO2) films in an economical way is of interest to realizing the application of smart windows. Here, we reported a successful preparation of self-assembly VO2 nanoplate films on TiO2-buffered glass by a facile hydrothermal process. The VO2 films composed of triangle-shaped plates standing on substrates exhibit a self-generated porous structure, which favors the transmission of solar light. The porosity of films is easily controlled by changing the concentration of precursor solutions. Excellent thermochromic properties are observed with visible light transmittance as high as 70.3% and solar modulating efficiency up to 9.3% in a VO2 film with porosity of ~35.9%. This work demonstrates a promising technique to promote the commercial utilization of VO2 in smart windows.
Urinary miR-16 transactivated by C/EBPβ reduces kidney function after ischemia/reperfusion–induced injury
Authors: Chen Hsi-Hsien , Lan Yi-Fan , Li Hsiao-Fen , Cheng Ching-Feng , Lai Pei-Fang , Li Wei-Hua , Lin Heng
Published: June 2016

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is regulated by transcriptional factors and microRNAs (miRs). However, modulation of miRs by transcriptional factors has not been characterized in AKI. Here, we found that urinary miR-16 was 100-fold higher in AKI patients. MiR-16 was detected earlier than creatinine in mouse after I/R. Using TargetScan, the 3′UTR of B-cell lymphoma 2 (BCL-2) was found complementary to miR-16 to decrease the fluorescent reporter activity. Overexpression of miR-16 in mice significantly attenuated renal function and increased TUNEL activity in epithelium tubule cells. The CCAAT enhancer binding protein beta (C/EBP-β) increased the expression of miR-16 after I/R injury. The ChIP and luciferase promoter assay indicated that about −1.0 kb to −0.5 kb upstream of miR-16 genome promoter region containing C/EBP-β binding motif transcriptionally regulated miR-16 expression. Meanwhile, the level of pri-miR-16 was higher in mice infected with lentivirus containing C/EBP-β compared with wild-type (WT) mice and overexpression of C/EBP-β in the kidney of WT mice reduced kidney function, increased kidney apoptosis, and elevated urinary miR-16 level. Our results indicated that miR-16 was transactivated by C/EBP-β resulting in aggravated I/R induced AKI and that urinary miR-16 may serve as a potential biomarker for AKI.
Capacity of very noisy communication channels based on Fisher information
Authors: Duan Fabing , Chapeau-Blondeau François , Abbott Derek
Published: June 2016

We generalize the asymptotic capacity expression for very noisy communication channels to now include coloured noise. For the practical scenario of a non-optimal receiver, we consider the common case of a correlation receiver. Due to the central limit theorem and the cumulative characteristic of a correlation receiver, we model this channel noise as additive Gaussian noise. Then, the channel capacity proves to be directly related to the Fisher information of the noise distribution and the weak signal energy. The conditions for occurrence of a noise-enhanced capacity effect are discussed and the capacity difference between this noisy communication channel and other nonlinear channels is clarified.
A rapid and practical technique for real-time monitoring of biomolecular interactions using mechanical responses of macromolecules
Authors: Tarhan Mehmet C. , Lafitte Nicolas , Tauran Yannick , Jalabert Laurent , Kumemura Momoko , Perret Grégoire , Kim Beomjoon , Coleman Anthony W. , Fujita Hiroyuki , Collard Dominique
Published: June 2016

Monitoring biological reactions using the mechanical response of macromolecules is an alternative approach to immunoassays for providing real-time information about the underlying molecular mechanisms. Although force spectroscopy techniques, e.g. AFM and optical tweezers, perform precise molecular measurements at the single molecule level, sophisticated operation prevent their intensive use for systematic biosensing. Exploiting the biomechanical assay concept, we used micro-electro mechanical systems (MEMS) to develop a rapid platform for monitoring bio/chemical interactions of bio macromolecules, e.g. DNA, using their mechanical properties. The MEMS device provided real-time monitoring of reaction dynamics without any surface or molecular modifications. A microfluidic device with a side opening was fabricated for the optimal performance of the MEMS device to operate at the air-liquid interface for performing bioassays in liquid while actuating/sensing in air. The minimal immersion of the MEMS device in the channel provided long-term measurement stability (>10 h). Importantly, the method allowed monitoring effects of multiple solutions on the same macromolecule bundle (demonstrated with DNA bundles) without compromising the reproducibility. We monitored two different types of effects on the mechanical responses of DNA bundles (stiffness and viscous losses) exposed to pH changes (2.1 to 4.8) and different Ag+ concentrations (1 μM to 0.1 M).
Dendrite Suppression by Shock Electrodeposition in Charged Porous Media
Authors: Han Ji-Hyung , Wang Miao , Bai Peng , Brushett Fikile R. , Bazant Martin Z.
Published: June 2016

It is shown that surface conduction can stabilize electrodeposition in random, charged porous media at high rates, above the diffusion-limited current. After linear sweep voltammetry and impedance spectroscopy, copper electrodeposits are visualized by scanning electron microscopy and energy dispersive spectroscopy in two different porous separators (cellulose nitrate, polyethylene), whose surfaces are modified by layer-by-layer deposition of positive or negative charged polyelectrolytes. Above the limiting current, surface conduction inhibits growth in the positive separators and produces irregular dendrites, while it enhances growth and suppresses dendrites behind a deionization shock in the negative separators, also leading to improved cycle life. The discovery of stable uniform growth in the random media differs from the non-uniform growth observed in parallel nanopores and cannot be explained by classic quasi-steady “leaky membrane” models, which always predict instability and dendritic growth. Instead, the experimental results suggest that transient electro-diffusion in random porous media imparts the stability of a deionization shock to the growing metal interface behind it. Shock electrodeposition could be exploited to enhance the cycle life and recharging rate of metal batteries or to accelerate the fabrication of metal matrix composite coatings.
Size-, electric-field- and frequency-dependent third-order nonlinear optical properties of hydrogenated silicon nanoclusters
Authors: Li Haipeng , Xu Hu , Shen Xiaopeng , Han Kui , Bi Zetong , Xu Runfeng
Published: June 2016

We investigated the electronic properties and second hyperpolarizabilities of hydrogenated silicon nanoclusters (H-SiNCs) by using the density functional theory method. The effects of cluster size, external electric field and incident frequency on the second hyperpolarizability were also examined, respectively. We found that small H-SiNCs exhibit large second hyperpolarizability. With the increase of the number of silicon atoms in H-SiNCs, the frontier molecular orbital energy gap decreases, attributed to the enhancement of the second hyperpolarizability. Interestingly, we also found the electric-field-induced gigantic enhancement of the second hyperpolarizability for H-SiNCs due to the change of electron density distributions. In addition, our results demonstrate a significant dependence on the frequency of incident light.
Polarizability of the active site of cytochrome c reduces the activation barrier for electron transfer
Authors: Dinpajooh Mohammadhasan , Martin Daniel R. , Matyushov Dmitry V.
Published: June 2016

Enzymes in biology’s energy chains operate with low energy input distributed through multiple electron transfer steps between protein active sites. The general challenge of biological design is how to lower the activation barrier without sacrificing a large negative reaction free energy. We show that this goal is achieved through a large polarizability of the active site. It is polarized by allowing a large number of excited states, which are populated quantum mechanically by electrostatic fluctuations of the protein and hydration water shells. This perspective is achieved by extensive mixed quantum mechanical/molecular dynamics simulations of the half reaction of reduction of cytochrome c. The barrier for electron transfer is consistently lowered by increasing the number of excited states included in the Hamiltonian of the active site diagonalized along the classical trajectory. We suggest that molecular polarizability, in addition to much studied electrostatics of permanent charges, is a key parameter to consider in order to understand how enzymes work.
Endomembrane-associated RSD-3 is important for RNAi induced by extracellular silencing RNA in both somatic and germ cells of Caenorhabditis elegans
Authors: Imae Rieko , Dejima Katsufumi , Kage-Nakadai Eriko , Arai Hiroyuki , Mitani Shohei
Published: June 2016

RNA silencing signals in C. elegans spread among cells, leading to RNAi throughout the body. During systemic spread of RNAi, membrane trafficking is thought to play important roles. Here, we show that RNAi Spreading Defective-3 (rsd-3), which encodes a homolog of epsinR, a conserved ENTH (epsin N-terminal homology) domain protein, generally participates in cellular uptake of silencing RNA. RSD-3 is previously thought to be involved in systemic RNAi only in germ cells, but we isolated several deletion alleles of rsd-3, and found that these mutants are defective in the spread of silencing RNA not only into germ cells but also into somatic cells. RSD-3 is ubiquitously expressed, and intracellularly localized to the trans-Golgi network (TGN) and endosomes. Tissue-specific rescue experiments indicate that RSD-3 is required for importing silencing RNA into cells rather than exporting from cells. Structure/function analysis showed that the ENTH domain alone is sufficient, and membrane association of the ENTH domain is required, for RSD-3 function in systemic RNAi. Our results suggest that endomembrane trafficking through the TGN and endosomes generally plays an important role in cellular uptake of silencing RNA.
An excellent navigation system and experience in craniomaxillofacial navigation surgery: a double-center study
Authors: Dai Jiewen , Wu Jinyang , Wang Xudong , Yang Xudong , Wu Yunong , Xu Bing , Shi Jun , Yu Hongbo , Cai Min , Zhang Wenbin , Zhang Lei , Sun Hao , Shen Guofang , Zhang Shilei
Published: June 2016

Numerous problems regarding craniomaxillofacial navigation surgery are not well understood. In this study, we performed a double-center clinical study to quantitatively evaluate the characteristics of our navigation system and experience in craniomaxillofacial navigation surgery. Fifty-six patients with craniomaxillofacial disease were included and randomly divided into experimental (using our AccuNavi-A system) and control (using Strker system) groups to compare the surgical effects. The results revealed that the average pre-operative planning time was 32.32 mins vs 29.74 mins between the experimental and control group, respectively (p > 0.05). The average operative time was 295.61 mins vs 233.56 mins (p > 0.05). The point registration orientation accuracy was 0.83 mm vs 0.92 mm. The maximal average preoperative navigation orientation accuracy was 1.03 mm vs 1.17 mm. The maximal average persistent navigation orientation accuracy was 1.15 mm vs 0.09 mm. The maximal average navigation orientation accuracy after registration recovery was 1.15 mm vs 1.39 mm between the experimental and control group. All patients healed and their function and profile improved. These findings demonstrate that although surgeons should consider the patients’ time and monetary costs, our qualified navigation surgery system and experience could offer an accurate guide during a variety of craniomaxillofacial surgeries.
A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish
Authors: Hong SoonGweon , Lee Philip , Baraban Scott C. , Lee Luke P.
Published: June 2016

Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Although fecundity, breeding convenience, genetic homology and optical transparency have been key advantages, laborious and invasive procedures are required for electrophysiological studies. Using an electrode-integrated microfluidic system, here we demonstrate a novel multichannel electrophysiology unit to record multiple zebrafish. This platform allows spontaneous alignment of zebrafish and maintains, over days, close contact between head and multiple surface electrodes, enabling non-invasive long-term electroencephalographic recording. First, we demonstrate that electrographic seizure events, induced by pentylenetetrazole, can be reliably distinguished from eye or tail movement artifacts, and quantifiably identified with our unique algorithm. Second, we show long-term monitoring during epileptogenic progression in ascn1labmutant recapitulating human Dravet syndrome. Third, we provide an example of cross-over pharmacology antiepileptic drug testing. Such promising features of this integrated microfluidic platform will greatly facilitate high-throughput drug screening and electrophysiological characterization of epileptic zebrafish.
Super-resolution fluorescent materials: an insight into design and bioimaging applications
Authors: Yang Zhigang , Sharma Amit , Qi Jing , Peng Xiao , Lee Dong Yeop , Hu Rui , Lin Danying , Qu Junle , Kim Jong Seung
Published: June 2016

With the emerging of super-resolution fluorescent imaging microscopy techniques, biological targets below 200 nm in size are successful to be localized clearly and precisely with unprecedented details. In this tutorial review, the fluorescent materials, including organic fluorophores and nanomaterials, utilized in STED, single molecule localized microscopy (PALM/STORM) and SOFI microscopies, together with their working principles are mainly discussed.
Acoustically-driven thread-based tuneable gradient generators
Authors: Ramesan Shwathy , Rezk Amgad R. , Cheng Kai Wei , Chan Peggy P. Y. , Yeo Leslie Y.
Published: June 2016

Dynamically tuneable concentration gradients are demonstrated in a thread-based microfluidic network that can be embedded in a three-dimensional hydrogel construct to mimic in vivo tissue microenvironments.
Cell membrane penetration and mitochondrial targeting by platinum-decorated ceria nanoparticles
Authors: Torrano Adriano A. , Herrmann Rudolf , Strobel Claudia , Rennhak Markus , Engelke Hanna , Reller Armin , Hilger Ingrid , Wixforth Achim , Bräuchle Christoph
Published: June 2016

Platinum-decorated ceria nanoparticles of ∼50 nm can rapidly penetrate cell plasma membranes and reach intracellular organelles, such as mitochondria.
A persistent luminescence microsphere-based probe for convenient imaging analysis of dopamine
Authors: Tang Jie , Su Yingying , Deng Dongyan , Zhang Lichun , Yang Na , Lv Yi
Published: June 2016

SrMgSi2O6:Eu0.01,Dy0.02 persistent luminescence microspheres have been synthesized via a simple template method and a new probe was established based on turn-off of the persistent luminescence emission for detection and optical imaging of dopamine.
Engaging electronic effects for atropselective [5+2]-photocycloaddition of maleimides
Authors: Raghunathan Ramya , Kumarasamy Elango , Jockusch Steffen , Ugrinov Angel , Sivaguru J.
Published: June 2016

Atropisomeric maleimides were synthesized and subjected to atropselective [5+2]-photocycloaddition under direct irradiation to yield azepinone products with high enantio- (ee >98%) and diastereoselectivity (dr >98%).
Synthesis of a highly active oxidation catalyst with improved distribution of titanium coordination states
Authors: Wu Lizhi , Deng Xiujuan , Zhao Shufang , Yin Hanmei , Zhuo Zuoxi , Fang Xiangqing , Liu Yueming , He Mingyuan
Published: June 2016

A facile strategy was carried out to construct a high-performance titanosilicate oxidation catalyst with optimized distribution of titanium coordination states.
Characterization of a trinuclear ruthenium species in catalytic water oxidation by Ru(bda)(pic)2 in neutral media
Authors: Zhang Biaobiao , Li Fei , Zhang Rong , Ma Chengbing , Chen Lin , Sun Licheng
Published: June 2016

A RuIII–O–RuIV–O–RuIII type trinuclear intermediate was crystallographically characterized in catalytic water oxidation. Hindering the formation of the trinuclear intermediate by pH adjustment led to a great improvement in the catalytic activity.
New M- and V-shaped perylene diimide small molecules for high-performance nonfullerene polymer solar cells
Authors: Park Gi Eun , Kim Hyung Jong , Choi Suna , Lee Dae Hee , Uddin Mohammad Afsar , Woo Han Young , Cho Min Ju , Choi Dong Hoon
Published: June 2016

New M- and V-shaped perylene diimide (PDI)-based small molecules were synthesized as new n-type acceptors for nonfullerene-based polymer solar cells.
Engineering an iridium-containing metal–organic molecular capsule for induced-fit geometrical conversion and dual catalysis
Authors: Li Xuezhao , Wu Jinguo , Chen Liyong , Zhong Xiaoming , He Cheng , Zhang Rong , Duan Chunying
Published: June 2016

Quantitative dynamic capsule–capsule conversion by cooperative binding one carbonate anion and switchable dual catalysis was achieved within an Ir2Co3-type capsule.
Understanding the wettability of a hairy surface: effect of hair rigidity and topology
Authors: Pei Han-Wen , Liu Hong , Zhu You-Liang , Lu Zhong-Yuan
Published: June 2016

We present a computer simulation study on the wettability of a hairy surface with different topological structures such as single hairs, hair bundles and network structure.
Fe-doped Beta zeolite from organotemplate-free synthesis for NH3-SCR of NOx
Authors: Zhu Yongjun , Chen Bingbing , Zhao Rongrong , Zhao Qi , Gies Hermann , Xiao Feng-Shou , De Vos Dirk , Yokoi Toshiyuki , Bao Xinhe , Kolb Ute , Feyen Mathias , Maurer Stefan , Moini Ahmad , Müller Ulrich , Shi Chuan , Zhang Weiping
Published: June 2016

Structure–performance correlations suggest that the content of isolated Fe3+ in the Beta zeolite affects the SCR activity directly.
Lewis acid–base adducts of group 13 elements: synthesis, structure and reactivity toward benzaldehyde
Authors: Ganesamoorthy C. , Matthias M. , Bläser D. , Wölper C. , Schulz S.
Published: June 2016

[LGa-M(C6F5)3] (M = B1, Al2, Ga3) reacts with benzaldehyde in different ways including the formation of the zwitterionic species [LGa(C6F5){CH(Ph)(OAl(C6F5)2)}] (5).
Antimony(v) cations for the selective catalytic transformation of aldehydes into symmetric ethers, α,β-unsaturated aldehydes, and 1,3,5-trioxanes
Authors: Arias Ugarte Renzo , Devarajan Deepa , Mushinski Ryan M. , Hudnall Todd W.
Published: June 2016

1-Diphenylphosphinonaphthyl-8-triphenylstibonium triflate ([2][OTf]) was prepared in excellent yield. This antimony(v) cation was found to selectively catalyze the transformation of aldehydes into symmetric ethers, α,β-unsaturated aldehydes, and 1,3,5-trioxanes.
Likelihood of climate change pathways under uncertainty on fossil fuel resource availability
Authors: Capellán-Pérez Iñigo , Arto Iñaki , Polanco-Martínez Josué M. , González-Eguino Mikel , Neumann Marc B.
Published: June 2016

The consideration of the entire range of revised estimates of fossil fuels resources shows that their depletion is likely to occur during the 21st century accelerating the transition to renewable energy sources but not alleviating the need for urgent climate action.
Accelerated dephosphorylation of adenosine phosphates and related compounds in the presence of nanocrystalline cerium oxide
Authors: Janoš Pavel , Lovászová Iveta , Pfeifer Jan , Ederer Jakub , Došek Marek , Loučka Tomáš , Henych Jiří , Kolská Zdeňka , Milde David , Opletal Tomáš
Published: June 2016

Some forms of (nano)ceria promote the cleavage of the phosphoester bonds in mono- and dinucleotides under biologically relevant conditions.
Triclosan adsorption using wastewater biosolids-derived biochar
Authors: Tong Yiran , Mayer Brooke K. , McNamara Patrick J.
Published: June 2016

Wastewater biosolids can be converted to a resource and used to remove micropollutants from wastewater.
A method for simultaneous bioflocculation and pretreatment of algal biomass targeting improved methane production
Authors: Prajapati Sanjeev Kumar , Bhattacharya Arghya , Kumar Pushpendar , Malik Anushree , Vijay Virendra Kumar
Published: June 2016

A novel fungi mediated method for simultaneous bioflocculation and pretreatment of algae, to improve the methane yield, is revealed.
Synchrotron radiation contribution to the study of aluminium corrosion layers of air and space museum aircrafts for their preservation
Authors: Mirambet F. , Vantelon D. , Reguer S. , Rocca E.
Published: June 2016

To improve the conservation of aluminium made materials in museum collections, the chemical composition and the electrochemical behaviour of corrosion product layers collected on aircrafts exposed for decades to climatic changes were investigated.
A reconfigurable continuous-flow fluidic routing fabric using a modular, scalable primitive
Authors: Silva Ryan , Bhatia Swapnil , Densmore Douglas
Published: June 2016

Using a single primitive (A., B.) we created an algorithmically scalable (D.) reconfigurable routing fabric (E.) for continuous-flow microfluidic devices capable of arbitrary routing.
In situ fluorescence of lac dye stabilized gold nanoparticles; DNA binding assay and toxicity study
Authors: Pattanayak Sutanuka , Chakraborty Sharmila , Mollick Md. Masud Rahaman , Roy Indranil , Basu Samita , Rana Dipak , Gauri Samiran Sona , Chattopadhyay Dipankar , Chakraborty Mukut
Published: June 2016

In situsynthesis of natural lac stabilized AuNPs, having DNA interactions and antitoxicity properties: UV-Vis and fluorimetric studies.
Synthetic studies of callyspongiolide: synthesis of the macrolactone core of the molecule
Authors: Athe Sudhakar , Sharma Ashish , Marumudi Kanakaraju , Ghosh Subhash
Published: June 2016

Synthesis of the fully functionalized macrolactone core of the highly cytotoxic marine natural product callyspongiolide has been achievedviaaZ-selective intramolecular H–W–E reaction and allylic alkylation of an activatedZ-allylic alcoholviaan SN2′ fashion as key steps.
β-NaYF4:Yb,Tm: upconversion properties by controlling the transition probabilities at the same energy level
Authors: Li Min , Liu Xiaoyang , Liu Li , Ma Bing , Li Benxian , Zhao Xudong , Tong Wenming , Wang Xiaofeng
Published: June 2016

The influencing factors of the special upconversion properties of Tm3+ have been studied in the β-NaYF4:Yb,Tm system.
Preparation of rutile TiO2 by hydrolysis of TiOCl2 solution: experiment and theory
Authors: Liu Yahui , Shao Dawei , Wang Weijing , Yi Lingyun , Chen Desheng , Zhao Hongxin , Wu Jingyi , Qi Tao , Cao Chengbo
Published: June 2016

HCl can decompose CaTiO3-type titanium slag and obtain a TiOCl2 solution. By hydrolysis of TiOCl2, rutile TiO2 can be prepared according to the structural rearrangement: (Ti2O2)(H2O)4Cl4–Ti(OH)(H2O)2Cl3–Ti(OH)2Cl2–rutile-type Ti(OH)2Cl2–rutile TiO2.
Facile synthesis of functional poly(vinylene sulfide)s containing donor–acceptor chromophores by a double click reaction
Authors: Wang Dong , Guo Qingsen , Gao Hong , Yang Zhou , Cao Hui , He Wanli , Wang Huihui
Published: June 2016

The new electronically active poly(vinylene sulfide)s containing dialkylaniline-substituted electron-rich alkynes in the side chains were designed and synthesized by the ‘thiol-click’ polymerization.
New insights into an innovative Auricularia auricular polysaccharide pH-sensitive hydrogel for controlled protein drug delivery
Authors: Yu Yibin , Pan Hao , Wang Yingying , Xiong Wei , Zhang Qiantao , Chen Kai , Gai Xiumei , Li Pingfei , Yang Xinggang
Published: June 2016

An innovative pH-sensitive Auricularia auricular polysaccharide hydrogel was developed for effective controlled protein delivery for the first time.
Reactivity of nanoceria particles exposed to biologically relevant catechol-containing molecules
Authors: Bülbül Gonca , Hayat Akhtar , Liu Xiaobo , Andreescu Silvana
Published: June 2016

The interaction of nanoceria with catecholic molecules was investigated to obtain mechanistic information of the surface reactivity of these particles, and develop predictive models of their behavior and potential effects in complex environments.
Facile preparation of amidoxime-functionalized fiber by microwave-assisted method for the enhanced adsorption of chromium(vi) from aqueous solution
Authors: Deng Sheng , Zhang Guangshan , Li Yang , Dou Yuan , Wang Peng
Published: June 2016

In this study, a facile and highly efficient approach, the microwave-assisted (MW-aid) method, was applied for the synthesis of amidoxime-functionalized fibrous adsorbent, which exhibited enhanced adsorption capacities for Cr(vi) in aqueous solution.
Facile synthesis of photoactive diaryl(hetaryl)cyclopentenes by ionic hydrogenation
Authors: Lvov Andrey G. , Bulich Ekaterina Yu. , Metelitsa Anatoly V. , Shirinian Valerii Z.
Published: June 2016

A facile synthetic approach to photoactive diarylethenes comprising a cyclopentene ring as an ethene bridge was developed based on reduction of 2,3-diaryl(hetaryl)cyclopent-2-en-1-ones through an ionic hydrogenation reaction.
Main chain poly(bile acid) directed plasmonic nanospheres with amphiphilic binding pockets and photo-triggered destruction
Authors: Sun Jinzhi , Li Weina , Xiao Lin , Yu Guanghui , Shi Jinsheng
Published: June 2016

A series of sulfide-bridged main chain poly(bile acid)s were developed and biologically sourced amphiphilic homopolymer-directed plasmonic nanospheres and their properties were investigated.
Controlled functionalization of graphene with carboxyl moieties toward multiple applications
Authors: Miao Zhongzheng , Li Xianglong , Zhi Linjie
Published: June 2016

A controlled functionalization strategy is exploited for producing solution-processable carboxyl-rich functionalized graphene without sacrificing the structural integrity, providing a unique and universal material platform for diverse applications.
Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation
Authors: Faustino Hélio , Silva Maria J. S. A. , Veiros Luís F. , Bernardes Gonçalo J. L. , Gois Pedro M. P.
Published: June 2016

Formyl benzeno boronic acids rapidly and selectively react withN-terminal cysteines to yield a reversible boronated thiazolidine that may be used in the interactive orthogonal modification of peptides.
A polymer acceptor with an optimal LUMO energy level for all-polymer solar cells
Authors: Ding Zicheng , Long Xiaojing , Dou Chuandong , Liu Jun , Wang Lixiang
Published: June 2016

A new polymer acceptor based on the BNBP unit with an optimal LUMO energy level has been developed. The resulting all-polymer solar cells show high PCEs, remarkably highVocvalues and small photon energy losses.
Nanostructured catalysts for electrochemical water splitting: current state and prospects
Authors: Li Xiumin , Hao Xiaogang , Abudula Abuliti , Guan Guoqing
Published: June 2016

The fundamentals of water electrolysis, current popular electrocatalysts developed for cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER) in liquid electrolyte water electrolysis are reviewed and discussed.
Phase separation synthesis of trinickel monophosphide porous hollow nanospheres for efficient hydrogen evolution
Authors: Jin Lihuang , Xia Han , Huang Zhipeng , Lv Cuncai , Wang Jie , Humphrey Mark G. , Zhang Chi
Published: June 2016

A facile and scalable approach to synthesize trinickel monophosphide (Ni3P) porous hollow nanospheres (PHNs) has been developed, the resultant Ni3P PHNs exhibiting excellent catalytic activity in the hydrogen evolution reaction (HER).
Improvement of direct methanol fuel cell performance using a novel mordenite barrier layer
Authors: Al-Batty S. , Dawson C. , Shanmukham S. P. , Roberts E. P. L. , Holmes S. M.
Published: June 2016

The targeted addition of an ‘organophobe’ increases the power density of a direct methanol fuel cell by up to 50%.
Acene-linked covalent organic frameworks as candidate materials for singlet fission
Authors: Laszlo Viktor , Kowalczyk Tim
Published: June 2016

Embedding of acene linker units in 2D covalent organic frameworks shows promise in simulations as a novel route to singlet fission materials with high electron mobilities.
CuSCN as selective contact in solution-processed small-molecule organic solar cells leads to over 7% efficient porphyrin-based device
Authors: Morán Gabriela , Arrechea Susana , Cruz Pilar de la , Cuesta Virginia , Biswas Subhayan , Palomares Emilio , Sharma Ganesh D. , Langa Fernando
Published: June 2016

Two A–π–D–π–A small molecules with a zinc porphyrin donor core and 3-ethylrhodamine terminal were synthesized and used as donor for BHJ OSCs. The PCE over 7% was achieved using CuSCN as selective contact.
Bean pod-like Si@dopamine-derived amorphous carbon@N-doped graphene nanosheet scrolls for high performance lithium storage
Authors: Sun Wei , Wan Liu , Li Xiaocheng , Zhao Xinhong , Yan Xingbin
Published: June 2016

A bean pod-like void-containing Si@DDAC@N-GNS structure has been elaborately designed and synthesized, which demonstrates highly reversible capacity, excellent rate capability and good cycling stability.
Correction: Improving the efficiency of polymer solar cells via a treatment of methanol : water on the active layers
Authors: Guo Biao , Zhou Weilong , Wu Mengchun , Lv Junjie , Yu Chengzhuo , Li Fenghong , Hu Zhonghan
Published: June 2016

Correction for ‘Improving the efficiency of polymer solar cells via a treatment of methanol : water on the active layers’ by Biao Guo et al., J. Mater. Chem. A, 2016, DOI: 10.1039/c6ta04026h.
Biomolecular recognition at the cellular level: geometrical and chemical functionality dependence of a low phototoxic cationic probe for DNA imaging
Authors: Gaur Pankaj , Kumar Ajay , Bhattacharyya Shalmoli , Ghosh Subrata
Published: June 2016

Potential application of a biocompatible and low phototoxic cationic stain with semilunar geometry for longer duration visualization of cellular DNA is reported.
High selectivity in water soluble MoS2 quantum dots for sensing nitro explosives
Authors: Haldar Dhrubaa , Dinda Diptiman , Saha Shyamal Kumar
Published: June 2016

Rapid and highly selective detection of Aromatic Nitro explosive Trinitrophenol by amine functionalized MoS2 QDs.
Fine‐grained hardware switching scheme for power reduction in multiplication
Authors: Huang Y. , Li C. , Li M. , Van der Perre L. , Dehaene W.
Published: June 2016

This Letter presents a fine‐grained hardware switching scheme to choose from the proper hardware for low power computing. It exploits the word‐length optimisation opportunities for multiplication unit. With the proposed technique, the gate‐level simulation result on OpenRISC shows 23.7% power reduction for the multiplication unit, which accounts for 9.5% power reduction for its execution unit.
DHL‐cache: dynamic per history length adjustment for low‐power L2 cache
Authors: Joo H.W. , Chung E.Y.
Published: June 2016

The significant power dissipation of the on‐chip L2 cache is a major concern in modern microprocessors. This Letter proposes a unique low‐power technique for a high‐associative large L2 cache that has fragmented locality by L1 cache. The dynamic per history length adjustment cache (DHL‐cache) dynamically selects the qualified way candidates to be accessed and controls the way‐prediction window size based on the access history pattern. With a high degree of the way‐prediction accuracy, the DHL‐cache shows a 55.3% energy‐delay product improvement over the location‐cache with minimum hardware support. Therefore, the DHL‐cache alleviates the power limit issue for L2 cache, even with high associativity and fragmented locality.
Quadrotor circumnavigation of an unknown moving target using camera vision‐based measurements
Authors: Ghommam Jawhar , Fethalla Nuradeen , Saad Maarouf
Published: June 2016

This study proposes a vision‐based motion estimation and target tracking algorithm for a quadrotor unmanned aerial vehicle circumnavigation around a moving mobile target whose velocity is unknown and time varying. In this study, the authors assume that the quadrotor is equipped with onboard downward‐looking camera, as a means to determine position of the quadrotor relative to the target. The proposed circumnavigation control algorithm relies essentially on two distinct phases, namely the virtual target tracking and the circumnavigation phase. To prepare for these phases, a predefined sphere, with a desired radius having the moving target position as its centre, is constructed along with a virtual target point that can move on its surface. During the whole tracking procedure, the quadrotor is first commanded to reach the virtual target point located at the projection of the ground vehicle's position onto the surface area of the sphere. When the quadrotor's position and velocity approaches the virtual target point with a given accuracy, the second phase is initiated to provide the quadrotor with more precise guidance to start orbiting at a specific height from level ground around the moving target. In this manner, the virtual target point is given the ability to manoeuvre itself in a circular motion above the moving target. The developed orbit manoeuvre uses an estimate of the moving target's velocity, obtained from a predictor scheme able to achieve velocity estimation as fast as possible.
Current‐estimation‐based iterative algorithms for solving periodic Lyapunov matrix equations
Authors: Wu Ai‐Guo , Chang Ming‐Fang
Published: June 2016

In this study, two novel iterative algorithms are presented to solve the Lyapunov matrix equations appearing in discrete‐time periodic linear systems. In both algorithms, a weighted combination of the estimation in the last and the current steps is used to update the estimation of the unknown matrices. It is shown that the sequences generated by the proposed algorithms with zero initial conditions monotonically converge to the unique positive definite solution of the periodic Lyapunov matrix equation if the associated system is asymptotically stable. Finally, a numerical example is used to illustrate the effectiveness of the proposed algorithms.
Adaptive tracking control of uncertain switched non‐linear systems with application to aircraft wing rock
Authors: Huang Ran , Zhang Jinhui , Zhang Xu
Published: June 2016

This study proposes an adaptive control scheme for global tracking of a class of switched non‐linear systems involving unknown saturated‐like Prandtl–Ishlinskii (PI) hysteresis. The switching information is assumed to be unobservable. A bound estimation approach is introduced to circumvent the obstacle caused by unknown switching and PI hysteresis. It is shown that under arbitrary switching, the proposed controller guarantees all signals of the overall closed‐loop system are globally uniformly bounded, and the tracking error can converge to an arbitrarily small residual set. The proposed control scheme is tested on a typical wing rock system in the face of persistent aerodynamic parameter changes. Simulation results demonstrate suppression of the wing rock and exhibit better transient performance in comparison with some existing method.
Adaptive iterative learning reliable control for a class of non‐linearly parameterised systems with unknown state delays and input saturation
Authors: Ji Honghai , Hou Zhongsheng , Fan Lingling , Lewis Frank L.
Published: June 2016

An adaptive iterative learning reliable control (AILRC) strategy is developed in this study for a class of non‐linearly parameterised systems subject to unknown time‐varying state delays and input saturation as well as actuator faults. In regard to non‐linearly parameterised uncertainties, not only the non‐linearly parameterised controlled object, but also the non‐linearly parameterised input distribution matrix is investigated in this technical note. Without the need for precise system parameters or analytically estimating bound on actuator faults variables, the novel data‐driven AILRC is constructed by a non‐linear feedback term and a robust term. The non‐linear influence brought by actuator faults, input saturation and state delays can be compensated with the resultant algorithms. It is shown that the convergence of single‐input–single‐output and multiple‐input–multiple‐output systems is proved through a new time‐weighted Lyapunov–Krasovskii‐like composite energy function. The validity of the proposed AILRC is further verified by simulation.
Robust optimal transmission switching with the consideration of corrective actions for N − k contingencies
Authors: Ding Tao , Zhao Chaoyue
Published: June 2016

In order to achieve a better economic dispatch decision of the electricity generation while guaranteeing system security, the optimal transmission switching (OTS) has been proposed with the well‐known N‐k contingency security criterion. However, the challenge for treating the OTS problem considering N‐k contingencies lie in that it may lead to a conservative result, since the optimal solution should simultaneously satisfy all the sets of N‐k constraints. To address this problem, the corrective control with respect to different contingencies is utilised during the period when the transmission topology remains unchanged, which can be formulated as a two‐stage problem. Consequently, a two‐stage robust optimisation is employed to optimise the objective value under the worst contingency, so as to hedge against the contingency uncertainties. Comparison of the traditional N‐1 OTS and the proposed robust N‐1 OTS models on IEEE 30‐bus test system shows that the robust OTS model has less conservatism than the traditional OTS model with the help of corrective actions. Moreover, it illustrates that the proposed method can be fairly applicable to cases with even N‐k contingencies, which can facilitate the complexity of contingency analysis.