bluuebunny/crossref_metadata_2025 huggingface dataset:
Current approaches to risk assessment of chronic heart failure after myocardial infarction
Authors: Lozhkina N. G. , Mukaramov I. , Voskoboinikov Yu. E. , Khayurina T. B.
Published: July 2022

In the last decade, there has been an increase in the number of survivors of myocardial infarction (MI). However, the risk of developing chronic heart failure (CHF) remains high in this category of patients. Population aging and comorbidity further contribute to adverse outcomes. Optimization of approaches to identify predictors of postinfarction CHF is an important clinical task of modern medicine.

The aim of the investigation is to develop a method to assess the risk of CHF development after MI.

Material and Methods. The present analysis included 186 patients who underwent MI from January 2019 to January 2020: 86 patients with signs of CHF above functional class (FC) 2 (NYHA) (mean age 64.3 years) and 100 patients without signs of CHF or with CHF 1 (NYHA) (mean age 62.6 years) by day 30 of MI. A mathematical model of CHF risk after MI was built by factor and correlation analysis methods.

Results. A method for assessing CHF risk after a previous MI was developed. The proposed formula is programmed in Excel table processor and includes 5 indicators: presence of atrial fibrillation, Killip class of acute heart failure, triglycerides level, ST-segment elevation of electrocardiogram, left ventricular ejection fraction less than 45 %. The authors’ approach allows long-term personalized monitoring, taking into account the ranked contribution of each factor in a particular patient; it is characterized by high sensitivity, specificity, and accuracy.

Conclusion. The present study investigated the factors of formation of postinfarct chronic heart failure syndrome. An original mathematical formula for CHF risk estimation, including routine indices of MI patients, has been proposed. The approach allows personalized management of selected cohorts of patients – with increased and standard risk of postinfarction CHF.
Myocardial condition in overweight patients at different stages of rehabilitation after revascularization
Authors: Seitekova A. N. , Molotov-Luchanskiy V. B. , Toleubekov K. K. , Yekizhanova B. T.
Published: July 2022

The aim of the study was to study the dynamics of myocardial function indicators in overweight patients at different stages of rehabilitation after coronary revascularization.

Material and methods. This article presents the interim results of prospective study which was conducted at the Tulpar cardiorehabilitation center (Karaganda, Kazakhstan). The study included 135 patients after restoration of blood flow in the coronary arteries (coronary artery bypass grafting, stenting). The average age was 58 ± 6 years. Exclusion criteria: acute myocardial infarction; chronic heart failure, functional class III–IV; acute disorders of cerebral circulation; diabetes mellitus in a state of decompensation; obesity I–III degree. We observed patients in dynamics at three stages of rehabilitation. 41 patients were included in the study at the first stage, 43 – at the second stage and 51 – at the third stage. Patients were included from different stages of rehabilitation. The groups were comparable in terms of the parameters of the structural and functional state of the myocardium, the same age range.

Results. Considering the size of the interventricular septum, the posterior wall of the left ventricle, the relative thickness of the myocardium and the myocardial mass index, it can be noted that statistically significant hypertrophy of the left ventricle was observed in all observation periods (p < 0.05).

Conclusions. In overweight patients who underwent myocardial revascularization surgery, persistent changes in the myocardium remain at the 3rd stage of rehabilitation
Adipokines/cytokines and disturbances in lipid metabolism
Authors: Spiridonov A. N. , Khudiakova A. D. , Ragino Yu. I.
Published: July 2022

This review presents the results of investigations in the field of studying the association of adipokines secreted by visceral adipocytes and the level of low-density lipoprotein cholesterol. In relation to this association, such adipokines as adiponectin, plasminogen activator inhibitor 1 (PAI-1), resistin, interleukin 1 beta (IL-1β), monocyte-chemoattractant protein type 1 (MCP-1), nerve growth factor (NGF), visfatin, omentin-1, and the pancreatic hormone insulin were analyzed. The results of studies that have studied the pathogenetic (in animal models) and clinical role of this association in humans are presented. Information on the topic from the publications of the PubMed, Google Scholar databases was used.
Los nuevos retos en la ingeniería sanitaria en Perú: Pandemia COVID-19 y enseñanza remota
Authors: Godiño Poma Francisco Cyl , Godiño Poma Milka Gloria
Published: July 2022

La Ingeniería Sanitaria surge como una rama de la ingeniería que involucra tanto materias propias de la ingeniería tales como: matemáticas, física, química hidráulica o mecánica, como aquellas relacionada con la medicina y la higiene, tales como la microbiología y conservación. Tiene como función principal crear y fomentar condiciones de salubridad en las poblaciones siendo vigilante de las aguas, el aire y la tierra, evitando que la contaminación alcance a los seres humanos. En Perú, la ingeniería sanitaria se creó como un apéndice de la ingeniería civil, pero pronto tomó el lugar merecido, declarándose una carrera de ingeniería independiente. Actualmente, la Ingeniería sanitaria es la encargada de llevar agua potabilizada a la población, y tratar las aguas servidas. Por otra parte, con la llegada del SARS-CoV-2, el mundo fue sacudido, y una situación de pandemia emergió, lo que hizo que los diferentes países tomasen las acciones necesarias, tal como sucedió con el Perú. Allí, la Ingeniería Sanitaria, accionó sus funciones, buscando la potabilización del agua de consumo. En estos tiempos de pandemia, tambien determinaron el resguardo de la población, lo que fomentó la educación remota. En el caso de la Ingeniería Sanitaria, los laboratorios presenciales y convencionales fueron sustituidos por laboratorios virtuales y remotos, lo cual permitió que la educación continuase sin contratiempos.
Geohelmintos y parámetros fisicoquímicos del suelo como indicadores de calidad ambiental en el distrito de José Crespo y Castillo, Huánuco
Authors: León Santa María Jonatan Estiff , Oré Cierto Luis Eduardo , Vertiz-Osores Jacinto Joaquin , Mendez-Ilizarbe Gliria Susana , Mercado-Marrufo Celia Emperatriz , Garcia Curo Gianmarco , Diaz Dumont Jorge Rafael
Published: July 2022

En la investigación se determinaron la presencia de geohelmintos y se evaluó la calidad ambiental del suelo mediante parámetros fisicoquímicos en el distrito de José Crespo y Castillo – Huánuco, Perú. Se detectaron y cuantificaron los geohelmintos, se caracterizó los perfiles modales y propiedades fisicoquímicas en función del Soil Taxonomy, y contraste con el estándar de calidad para el cadmio (Cd) y determinación del índice de calidad ambiental del suelo empleando el análisis de componentes principales. Los perfiles modales son Fluventic Eutrudepts, Lithic Udorthents, Typic Dystrudepts, Typic Dystrudepts - Lithic Udorthents, Typic Dystrudepts - Typic Endoaquents, Typic Endoaquents, Typic Eutrudepts - Typic Eutrudepts, Typic Udifluvents y Typic Udorthents; los parámetros fisicoquímicos textura, pH, materia orgánica, nitrógeno, fosforo disponible, potasio disponible, cadmio disponible, capacidad de intercambio catiónico efectivo, calcio, magnesio, aluminio, hidrogeno, bases y ácidos cambiables y porcentaje de saturación de aluminio, determinando que el cadmio disponible se encuentra dentro de los estándares de calidad ambiental del Perú; y el índice de calidad ambiental del suelo es de 41,48%, teniendo la calificación de un suelo regular de calidad ambiental. Y la contaminación por Ascaris lumbricoides fue en 25 de las calicatas (55,56%), presente en los 8 tipos de suelos catalogados, seguida de las unicinarias representadas por Necator americano y Ancylostoma duodenale en 14 calicatas (31,11%) de pH ligeramente a medianamente acido, y Taenias y Capilaria, ambos en el 8,29%; los geohelmintos como riesgo de salud pública, permanecen por largo de tiempo en el suelo, independientemente de la calidad y en amplios rangos de pH, favorecidos por niveles de sustratos orgánicos derivados de la antropogénesis.
Saturación de oxígeno versus índice de oxigenación: predictores de mortalidad en pacientes críticos con síndrome distrés respiratorio agudo por COVID-19
Authors: Bravo-Sotero María del Cielo Milagros , Vásquez-Tirado Gustavo Adolfo , Meregildo-Rodriguez Edinson Dante , Segura-Plasencia Niler Manuel , Arbayza-Ávalos Yessenia Katherin , Quispe-Castañeda Claudia Vanessa , Alva-Guarniz Hugo , Cuadra-Campos María del Carmen
Published: July 2022

Introducción: el COVID-19 es la causa más frecuente de SDRA generando cuadros clínicos leves, moderados y graves, en esta última, los pacientes podrían evolucionar a la necesidad de intubación orotraqueal y soporte ventilatorio avanzado; reportándose mortalidad de 26-90%, en estos casos. Es por ello, la necesidad de identificar factores de riesgos y herramientas predictores de mortalidad. En este estudio se determinó la validez diagnóstica de los índices de saturación de oxígeno y oxigenación como predictores de pronóstico de mortalidad en pacientes con SDRA severo por COVID-19 que requirieron de ventilación mecánica invasiva. Material y métodos: estudio transversal, analítico y retrospectivo. La muestra estuvo constituida por 176 historias clínicas de pacientes críticos. Se realizó análisis bivariado, y multivariado, además de determinar especificidad, sensibilidad, VPP, VPN y AUC. Resultados: 57,37% (101/176) de los pacientes fallecieron, con predominio del sexo masculino 79% (80/101); con edad promedio de 56 años. El lactato (p=0,115), no mostró asociación estadísticamente significativa. Contrariamente, en el análisis multivariado, el sexo masculino (p=0.04), glicemia (p=0,02) y, OI (p=0.00), arrojaron asociación. En cuanto a los índices, OSI registró sensibilidad y especificidad de 33% y 96% respectivamente; mientras que, IO tuvo 33,6% de sensibilidad y, 97,33% de especificidad; AUC 0,773 (IC: 0,677-0,868); es decir más del 77,3% de probabilidad de pronóstico a mortalidad. Conclusión: OSI y OI son adecuados predictores de mortalidad, teniendo OI mejor validez diagnóstico. Además, se ratifica, al sexo masculino y, aumento de valores glicémicos, como factores asociados a riesgo de desarrollar cuadros graves por COVID-19.
Infección por Helicobacter pylori y la hemorragia digestiva alta
Authors: Romero Parra Rosario Mireya , Barboza Arenas Luis Andres , Romero Chacín Jorge Luis , Cueva Parra Henry Antonio , Faría Romero José Antonio
Published: July 2022

Determinar la relación entre la infección por Helicobacter pylori y hemorragia digestiva alta (HDA) y su frecuencia fue el objetivo de la investigación, siendo ésta de tipo descriptivo correlacional con 50 pacientes con hemorragia digestiva, que acudieron al Servicio de Gastroenterología del Hospital Nacional Arzobispo Loayza de Perú, durante los meses de julio a octubre del 2021. Se elaboró un instrumento de recolección de información para las variables; edad, género, procedencia, ocupación y grado de instrucción. Se determinó la presencia de H. pylori a través de la realización de biopsia gástrica (identificación histopatológica). Para determinar la correspondencia entre las variables de la investigación, se utilizó la correlación de Pearson. Al evaluar el riesgo entre las patologías gastrointestinales y sufrir HDA se encontró para enfermedad ulcero péptica un (OR=7,1 IC: 1,394-35,987), gastritis (OR=13,7 IC: 1,068-174,81), y litiasis vesicular (OR=1,2 IC: 1,056-1,352). Dentro de los hábitos de los pacientes con HDA, 1 de cada 4 reportó consumir bebidas alcohólicas, 1 de cada 8 manifestó tabaquismo, y 1 de 2 reportó hábito cafeico. Se encontró una correlación positiva entre las variables hemorragia digestiva alta e infección por H. Pylori, ya que el coeficiente reportado es igual a 0,685. Se determinó una correlación positiva entre las variables hemorragia digestiva alta e infección por H. pylori en pacientes valorados por el servicio de gastroenterología del hospital. La infección por H. Pylori es de prevalencia elevada en la población general, sin embargo, el estudio muestra que no se manifiesta frecuentemente con sintomatología sangrante alta.
Evaluation of Barriers to Gilgit Baltistan's Travel & Tourism Industry: Pakistani Youth's Perception
Authors: Kharipzhanova Albina , Irfan Muhammad
Published: July 2022

Thousands of local and foreign tourists visit Gilgit-Baltistan (GB) which has huge tourist potential due to its unique beauty, but for being countryside area and new province, this region is facing different type of challenges and barriers towards its travel & tourism development. The current study intends to identifying and evaluate multiple varriers barriers to the development of GB's travel & tourism industry. Primary data was collected from Pakistani youth. The opinion of both men and women were sought. Later, the Grey Rational Analysis (GRA) model was used to analyse data and rank the barriers. The results showed that, absence of tourist information centres, limited and expensive flights and inability to regulate tourism & lack of effective tourism policy are key barriers hindering the development of GB. The results are important for GB's cultural & tourism department and for policy makers. Also, the results are important for the tour operators and the general public who want to visit GB.
Evaluation of Risks to Russian Food Supply Chains during the COVID-19
Authors: Ivanova Marina
Published: July 2022

The COVID-19 pandemic has demonstrated the vulnerability of global supply chains - the failure of one link in the supply chain can lead to numerous supply disruptions. The current study examines the main supply chain problems associated with the spread of the coronavirus and their ranking based on the perceived importance among the Russian shop owners. The study found the key factors of risks and uncertainty that might have disrupted the food supply chains in Russia during the COVID-19 pandemic and are source of food insecurity if not managed properly. These factors were identified through the literature, and later, based on the primary data collected from the grocery and catering shop owners in Russia, they were ranked using the Grey Relational Analysis model. The study found that traceability and logistical issues are perceived to be the most critical factors that have disrupted the food supply chain in the country.
New facts on consumer price rigidity in the Euro area
Authors: Petroulas Pavlos , Gautier Erwan , Fabo Brian , Menz Jan-Oliver , Roldan-Blanco Pau , Wieland Elisabeth , Conflitti Cristina , Fadejeva Ludmila , Messner Teresa , Rumler Fabio , Zimmer Helene , Faber Riemer P. , Jouvanceau Valentin , Santoro Sergio
Published: July 2022

Using CPI micro data for 11 euro area countries covering about 60% of the euro area consumption basket over the period 2010-2019, we document new findings on consumer price rigidity in the euro area: (i) each month on average 12.3% of prices change, which compares with 19.3% in the United States; when we exclude price changes due to sales, however, the proportion of prices adjusted each month is 8.5% in the euro area versus 10% in the United States; (ii) differences in price rigidity are rather limited across euro area countries but much larger across sectors; (iii) the median price increase (resp. decrease) is 9.6% (13%) when including sales and 6.7% (8.7%) when excluding sales; cross-country heterogeneity is more pronounced for the size than for the frequency of price changes; (iv) the distribution of price changes is highly dispersed: 14% of price changes in absolute values are lower than 2% whereas 10% are above 20%; (v) the overall frequency of price changes does not change much with inflation and does not react much to aggregate shocks; (vi) changes in inflation are mostly driven by movements in the overall size; when decomposing the overall size, changes in the share of price increases among all changes matter more than movements in the size of price increases or the size of price decreases. These findings are consistent with the predictions of a menu cost model in a low inflation environment where idiosyncratic shocks are a more relevant driver of price adjustment than aggregate shocks.
Podręcznik Pozytywnej Psychoterapii Psychodynamicznej
Authors: Boessmann Udo , Remmers Arno
Published: July 2022

Niniejsza książka jest w Niemczech od wielu lat bestsellerem w dziedzinie psychoterapii, zwłaszcza dla stażystów psychoterapii oraz terapeutów w procesie certyfikacji. Od pierwszych stron przedstawia ona jasno istotę psychoterapii psychodynamicznej. Jednak wiedza o pracy w przedstawionym tu podejściu może okazać się równie ważna i przydatna dla psychoterapeutów pracujących w nurcie humanistycznym. Czytelnik otrzymuje poręczny przegląd rozmaitych koncepcji psychoanalitycznych - aktualnych i naukowo dobrze udokumentowanych. Systematyczne i rygorystyczne przedstawienie takich zagadnień jak: diagnostyka, wyjaśnienie zadań terapeutycznych oraz określenie celu terapii, analiza przeniesienia i przeciwprzeniesienia, obrony czy oporu oraz techniki precyzyjnego formułowania hipotez dotyczących nieświadomego znaczenia i funkcji objawów zaburzeń psychicznych przypomina raczej pozycje bliskie terapeutom behawioralnym. Również planowanie leczenia przedstawiono w ujęciu ściśle praktycznym. Do ilustracji szerokiego wachlarza metod i technik terapeutycznych posłużono się analizą autentycznych przypadków. Koszty psychoterapii psychodynamicznej pokrywają w Niemczech od 1967 roku kasy chorych. Zebrane przez lata doświadczenie milionów pacjentów pozwoliło na solidne, systematyczne opracowanie koncepcji terapeutycznych oraz ram przeprowadzania terapii. Niemieckie doświadczenia mogą więc okazać się nad wyraz przydatne w pracy koleżanek i kolegów z innych krajów. Autorzy zdecydowali się na całkowite przeredagowanie książki, aby lepiej odpowiedzieć na potrzeby zagranicznych czytelników. Grupą docelową, dla której pozycja ta powinna być szczególnie wartościowa, są szkolacy się terapeuci i klinicyści, choć sięgają po nią w codziennej pracy również bardziej doświadczeni terapeuci.
Determinan jumlah penduduk miskin di Barlingmascakeb tahun 2012-2019
Authors: Corolina Natalia Nola , Sarfiah Sudati Nur , Panjawa Jihad Lukis
Published: July 2022

Creating a just, prosperous, and equitable life is the ultimate development goal in every country. Poverty is one of the problems in development and hinders these development goals. Barlingmascakeb is one of the development areas in Central Java province, which has a high number of poor people and poverty. This study aimed to analyze the effect of gross regional domestic product, inflation rate, human development index, and open unemployment rate on the poor population. The analytical method used in this research is panel data regression with a fixed-effect model approach. The results showed that the gross regional domestic product and the human development index had a significant adverse effect on the poor. The open unemployment rate had a significant positive effect on the number of the poor, and the inflation rate did not affect the number of the poor. The government’s role is needed to improve welfare, maintain the stability of the inflation rate, improve the quality of human development programs and increase training and skills programs to reduce the number of poor people.
Dampak penganguran, pendidikan, kesehatan, PDRB dan indeks pembangunan manusia terhadap kemiskinan di Indonesia
Authors: Aini Laily Nur , Islamy Sulaiha Nor
Published: July 2022

Poverty is a very complex social problem and one of the main problems faced by the Indonesian nation. This study aims to determine the effect of Unemployment, Education, Economic Growth (GDP), and the Human Development Index on Poverty in Indonesia. The quantitative research method uses panel data analysis with secondary data from the Central Statistics Agency of Indonesia. This study shows that unemployment and education do not affect poverty in Indonesia. The health variable shows that health affects poverty in Indonesia. The GDP variable shows the effect on poverty in Indonesia. The HDI variable shows the effect on poverty in Indonesia.
Determinan pengangguran usia muda
Authors: Putra Galang Ardian , Siti Aisyah
Published: July 2022

Youth unemployment is a challenge for development in Indonesia. As a country that is experiencing a demographic dividend, the issues of absorbing young workers are getting more attention. This study aims to analyze the effect of Gross Regional Domestic Product, provincial minimum wage, investment, inflation, and population on youth unemployment in provinces in Java and Sulawesi in 2011–2019. The analysis method used is panel data regression with the approach of the Random Effect Model (REM). The results show that the provincial minimum wage, inflation, and population have a positive and significant effect on youth unemployment in Java and Sulawesi in 2011–2019. Meanwhile, Gross Regional Domestic Product and investment proved to have no significant effect on youth unemployment.
Analisis faktor-faktor yang mempengaruhi produksi singkong di Kota Salatiga
Authors: Purnomo Didit , Kusuma Mahanara Puja
Published: July 2022

This study aims to analyze the effect of land area, fertilizer, and labor on cassava production in Argomulyo District, Salatiga City. This type of research is called quantitative research. The study was conducted in the Argomulyo District, Salatiga City. The population in this study were all farmers who planted cassava in the Argomulyo District of Salatiga City with rice fields, fields, and gardens. The research sample of 100 respondents was selected with random sampling techniques. Data collection techniques with a questionnaire. Data analysis techniques with multiple linear regression analysis and the classic assumption test. The results show that land area significantly affects cassava production in the Argomulyo District of Salatiga City. Fertilizer significantly affects cassava production in the Argomulyo District of Salatiga City. Labor has a significant effect on cassava production in Argomulyo District, Salatiga.
Analisis pengaruh industri pariwisata terhadap PDRB Jawa Tengah era pandemi covid-19
Authors: Andriyani Nur , Salam Annisa Nur
Published: July 2022

This study aims to analyze the influence of the tourism industry on PDRB in 35 districts/cities of Central Java during the 2020–2021 COVID-19 pandemic era. Secondary data is obtained from the Central Statistics Agency (BPS). The independent variables used are the number of tourist attractions, the number of domestic tourists, the number of foreign tourists, the number of restaurants, and the number of hotels and other accommodations. The dependent variable is the regional income of the tourism sector. The research method used is panel data regression with a fixed-effect model. The study results partially show that the variable number of tourist attractions and the number of hotels and other accommodations positively and significantly affect GRDP. The variable number of restaurants and the number of foreign tourists negatively and significantly affect GRDP. At the same time, domestic tourists have no significant effect on GRDP. Simultaneously, the variables of the number of tourist attractions, the number of domestic tourists, the number of foreign tourists, the number of restaurants, and the number of hotels and other accommodations affect the GRDP. Strenuous efforts are needed for the tourism industry to restore tourism performance to be more optimal in contributing to the economy.
The analyze of LQ45 companies stock price in 2018-2020
Authors: Samasta Almira Santi , Lestari Selvia Puji , Arsanda Tiara Daffa
Published: July 2022

This study aims to analyze how much Earning Per Share, Debt to Equity Ratio, and Return on Equity to stock prices in companies indexed by the 2018-2020 LQ45 period. The population of this study is the LQ45 companies that are consistently indexed in 2018-2020. The sample of this study uses purposive sampling. The sample in this study was 35 companies. The type of data used is secondary data derived from a summary of financial statement records. The analysis technique uses multiple linear regression analysis. The results of the study found that Earning Per Share had an effect on stock prices, while Debt to Equity Ratio and Return On Equity had no effect on stock prices for LQ45 indexed companies consistently in the 2018-2020 period.
Analisis faktor - faktor yang mempengaruhi pengambilan keputusan konsumen terhadap pembelian rumah
Authors: Santoso Fuji , Anas Zulviar
Published: July 2022

The increase in population causes an increase in the demand for housing. Many developers use the increasing need for houses to provide housing with various facilities. Various kinds of developer offer make the public as consumers are faced with several factors in the decision to buy a house. The purpose of the study was to determine the effect of price, building design, physical building, facilities, and location and to determine the dominant factors in home-buying decisions. The research method uses quantitative methods. The results showed that the price factor, the building design factor, the physical building factor, the facility factor, and the location factor influenced the decision to buy a house. The most dominant factor in influencing home-buying decisions is the price factor. Other influencing factors are location, building physical, facility, and building design factors.
Pelatihan manajemen pemasaran dan laporan keuangan umkm usaha kerajinan Desa Sidomukti Kabupaten Magetan
Authors: Silaturahmi Gati , Widiasmara Anny
Published: July 2022

In addition to being a profitable business, the Batik business can also preserve the culture of the Indonesian nation. Problems faced by the Batik Mukti Rahayu Joint Business Group (KUBE) in Sidomukti Village, Magetan Regency, which houses 22 batik artisans, marketing has only been limited to their circles or the surrounding community. In addition, KUBE's financial reports are done manually, so KUBE has not predicted its financial capacity. Seeing this, the 2021 Innovation Talent Team will conduct marketing training and operate a simple cash flow application. The method used is field observations, data collection, marketing training, and simple cash flow applications to make financial reports. These marketing training results are that Batik Mukti Rahayu craftsmen (KUBE) in Sidomukti Village, Plaosan District, Magetan Regency already have an Instagram account and a shop at Shopee. It can operate a simple cash flow application for financial reports. The "Pring Sedapur" motif, which is the icon of KUBE, can be recognized by many people and is a source of pride for the people of Magetan.
Pelatihan kewirausahaan inovasi pemasaran dan varian rasa era digital Desa Kedungmaron Kabupaten Madiun
Authors: Iskandar Dicky , Widiasmara Anny
Published: July 2022

Small and Medium Enterprises (SMEs) of tempeh chips in Madiun Regency are experiencing rapid development, including the "NAJA" tempeh chips produced by Mrs. Yuli. So far, the problems faced are only word-of-mouth promotion and have not done online marketing, and there are no product variants. The 2021 Innovation Talent Team conducts marketing innovation training based on Digital marketing in collaboration with Shopee Indonesia and provides flavor variants for tempeh chips. The method used is field observation, data collection, and training on Marketing Innovation, Flavor Variants, and Packaging. The results of consumer training are easier to view and order products via Instagram, Whatsapp and telephone by cooperating with Shopee E-commerce and making permits. This training also provides ways to make packaging neater and more efficient. Flavor variants include original taste, balado, roast beef, grilled corn, chicken onions, spicy. Tempe chips UKM "NAJA" can expand its business reach so that many people can recognize tempeh chips with various flavors, and the market share is getting wider.
Peningkatan Millenial Anti Bokek melalui capital market investment for beginners pada Siswa MAN 2 Magetan
Authors: Fitria Fitria , Ubaidillah Moh.
Published: July 2022

The low-middle economic family background makes the welfare of MAN 2 Magetan students far from qualified. The condition of students who are still in school and do not have the skills to make students unable to become freelancers. This community service activity aims to provide alternative solutions to student problems by providing knowledge and assistance regarding capital market investment so that students can get additional pocket money. The essence of this community service activity is the contribution in overcoming the mission, which is the implementation of the first SDG points. The implementation of this activity uses the blended meeting method, namely webinars (online) and training and direct assistance (offline). The results of this community service activity indicate an increase in knowledge and awareness of the urgency of capital market investment, as evidenced by the pre-test and post-test results on 24 participants. The evaluation results of the average value before the activity was 32.08, and after the activity became 62.08. Another result is skills regarding mutual fund stock trading.
Program renovasi dan pendampingan kelompok belajar untuk meningkatkan motivasi siswa pada masa pandemi covid-19 di Banjar Pacung Desa Sangeh Kecamatan Abiansemal, Kabupaten Badung Bali
Authors: Kariyana I Made , Pratama Octavianus Sumardana
Published: July 2022

Study group assistance was carried out to increase students' motivation studying in Adya Kids study groups during the Covid-19 pandemic. The current condition of the study area cannot be called a proper place to study, so it is necessary to renovate the building and improve infrastructure so that students can learn comfortably and increase their motivation for learning enthusiasm. The current pandemic is not expected to be a barrier for students to reach their dreams in the future. Students are invited to remain enthusiastic in understanding the material given at school. During pandemic the Covid-19, students can understand and apply the correct health protocols in carrying out learning activities. In addition, the existing old buildings need to be renovated and built-in conditions suitable for study. The results obtained in the mentoring of students' understanding of health protocols and increased interest in learning are indicated by good end-of-semester grades. In addition, the renovated building in the Adya Kids study group is also suitable and comfortable for students to study.
Pelatihan computational thinking guru MI se-Kecamatan Pabelan, Kabupaten Semarang
Authors: Kusumawati Erna Risfaula , Achmad Syaefudin
Published: July 2022

Learning in society 5.0 and the covid-19 pandemic requires several skills to be mastered, both by students and teachers. These skills are creativity, critical thinking, communication, collaboration, compassion, and computational thinking (6C). This paper describes the training carried out on teachers to improve computational thinking skills. A teacher must master computational thinking to prepare the next generation of potential, superior, and ready to face the era of society 5.0. The training target is MI teachers in Pabelan District, totaling 26 teachers. The training was divided into several stages, including a pretest, material presentation, practice working on logarithmic problems, creating a Bebras account, tutorial on making games using scratch software, and posttest. At the end of the activity, participants are asked to fill out a presence link as a condition to get a certificate. The training results showed that most of the participants could understand and implement computational thinking. It can be seen from the results of the posttest given. Participants were very enthusiastic and active in participating in the training. They were also happy because follow-up activities after the training were completed.
Pendampingan optimalisasi penggunaan google form untuk pembelajaran daring di masa pandemi
Authors: Djamdjuri Dewi Suriyani , Kholisah Fadia
Published: July 2022

Since the COVID-19 pandemic took place, the issue that teachers face, particularly in the regions, is a lack of knowledge in creating learning media that can be used in online learning. To overcome this problem, our team held training on making Google Form for elementary school teachers. The method we provide in this community service activity is by providing direct training to elementary school teachers and providing assistance in making learning media using the Google Form. The results of this service activity are that the teachers who participated in the training understood the technique of using, creating, and designing their own Google Form according to the needs of each subject as an online learning medium; all the teachers who participated in the training were happy, interested, and very enthusiastic about the Google Form training activities; and the results of the questionnaire completed by the teachers who attended the training showed that 90% of the teachers would apply Google Form as a medium of learning in teaching and learning activities.
醫療科技問題與病人安全風險學習平台成果與展望
Authors: 黃嘉立 黃嘉立 , Jia-Li Huang 鄧雅婷 , Ya-Ting Deng 洪聖惠
Published: July 2022

隨著科技的進步與智慧醫療的蓬勃發展，因資訊系統問題而導致的病人安全事件層出不窮，引起國際間重視。2020年醫策會與ECRI合作，建置台灣第一個醫療科技問題與病人安全風險學習平台(Information Technology related Patient Safety, ITPS)，由醫院通報以收集因資訊科技所導致的病人安全事件。本平台於2021年共收案50件，事件類別以檢驗／檢查／病理切片事件(40%)及藥物事件(38%)最多，在資通訊事件分類方面，以資訊系統問題(48%)、系統介面問題(26%)最多。為確保通報資料正確性與完整性，由專人客製化進行問題的溝通與釐清，並由專家群進行深度剖析，挖掘資訊系統潛藏的病人安全風險，提供即時的回饋與建議，並辦理醫院通報及改善經驗標竿分享，共同研討此新興領域，共創安全E世代。

 

With the rapid technology advancement and intense development of smart healthcare, patient safety incidents triggered by information technology related problems emerge in an endless stream, attracting international attention. In 2020, the Joint Commission of Taiwan (JCT) collaborated with the Emergency Care Research Institute (ECRI) to establish Taiwan’s first Information Technology related Patient Safety (ITPS). ITPS aims to collect information technology related patient safety incidents of healthcare organizations via reporting. In 2021, ITPS received a total of 50 incident cases, with the highest number of incidents in categories of inspection/examination/pathology (40%) and medication (38%). In terms of cause classification, the information system (48%) and system interface (26%) problems were the most common. In order to ensure the accuracy and integrity of the reported incident, a dedicated specialist will communicate with the hospital and clarify specific details of the incident. Then, an expert team will conduct in-depth analysis to identify potential patient safety risks in the hospital’s information system and provide immediate feedback and recommendations with final reports. The expert team will also invite hospitals to share their improvement benchmark experience, jointly explore this emerging field, and create a safe e-healthcare system within the country.

 
The Origins of the Romans 16 Doxology: Reconsidering Its Form and Provenance
Authors: Brewer J. Brittain
Published: July 2022

The doxology with which Paul concludes Romans is often judged inauthentic on thematic grounds and its unusual textual history. Though some have defended its Pauline origins, few have analyzed the doxology according to its liturgical structure. This article considers the formal features of the doxology as well as features of early Christian liturgy, suggesting that the doxology is best considered as a pre-Pauline liturgy that Paul adapted for his own purposes. Neither internal nor external evidence resolves the question of the doxology’s provenance. By considering the theological background and the formal criteria for homologies and hymns, a strong case can be made for the preexistence of the doxology. Preexistence best resolves the textual and stylistic tensions and explains the thematic overlap between the letter and the doxology. As a preexistent liturgical form, Rom 16:25–27 provides insight into the worship of the earliest Christians as well as the epistolary practices of Paul.
Effects of fruit thinning and some fruit and cladode components on fruit growth and fruit weight of cactus pear Opuntia ficus-indica (L.) Mill
Authors: Mohamed Arba  , Siham Farhat
Published: July 2022

The aim of this paper is to study the effect of fruit thinning and some fruit and cladode components on fruit growth and weight of cactus pear Opuntia ficus-indica (L.) Mill. The relationships between the fruit fresh weight and each of the parameters number of fruits per cladode, surface of cladodes and the dry weight of cladodes are studied. Experiments were carried out on an adult plantation of cactus pear in the Agadir area. Fruit thinning treatments used were: T: control without thinning, T1: thinning treatment of 6 fruits per cladode and T2: thinning treatment of 12 fruits per cladode. The size of cladodes used are: the small cladodes (C1), the medium cladodes (C2) and the large cladodes (C3). Obtained results showed that fruit thinning and the surface of cladodes and the interaction of the two factors have a significant effect (p ≤ 0.001) on fruit growth. On May 10, 2019, the highest rate of growth was obtained with the combination T1/C3 (thinning treatment T1 and large cladodes C3), with 1.6 cm for fruit length and 1 cm for fruit diameter, and the lowest rate of growth was obtained with the combination C1/T (not thinned plants and small cladodes C1) with 0.5 cm for fruit length and 0.3 cm for fruit diameter. The ratio dry weight of cladodes/ number of fruits per cladode has a significant effect (p ≤ 0.001) on the fruit fresh weight. The increase in the dry weight of cladodes and the reduction in the number of fruits per cladode leads to the production of fruits with large size. Positive linear relationships exist between the fruit fresh weight and the ratio dry weight of cladodes/ number of fruits per cladode, between the fruit fresh weight and the number of fruits per cladode, and between the fruit fresh weight and the surface of cladodes and the coefficient of determination R2 for each linear relationship is close to 1.
Frequency of Hypocalcemia after Thyroid Surgery
Authors: Butt Muhammad Bilal , Fayyaz Sana , . Quratulain , Balouch Varda , Sultan Waleed
Published: July 2022

Objective: The purpose of this study is to determine the prevalence of hypocalcemia among patients after thyroid surgery. Study Design: Descriptive study/ Cross-sectional Place and Duration: The study was conducted at the surgical department of Mayo Hospital, Lahore for the duration of eighteen months from July 2020 to December 2021. Methods: Fifty-five male and female subjects participated in this research. Patients ranged in age from 17 to 62 years. After obtaining written permission from the patient, demographic information such as age, sex, BMI, and tumors type was collected. Contralateral lobe cancer was also shown to be a problem. Before surgery and on the first post-operative day, the blood calcium levels of the patients were measured. Patients who received a full thyroidectomy were evaluated for signs of hypocalcemia. Analysis was performed using SPSS 22.0. Results: Among 55 patients, majority of the cases were females 30 (54.5%) were females and the rest were males 25 (45.5%). The patients mean age was 37.16±14.52 years and had mean BMI 24.45±6.62 kg/m2. Papillary cancer was the most common tumor found in 42 (76.4%) cases, followed by follicular cancer in 9 (16.4%) case and 4 (7.3%) cases had hurthle cell carcinoma. We found frequency of hypocalcemia in 14 (25.5%) cases. Among 14 patients of hypocalcemia 10 (71.4%) were females and 4 (38.6%) were males. Retrosternal of goiter found in 5 (35.7%) cases and no retrosternal extension found in 9 (64.3%) case. Post-operative other complications among all cases were seroma, transient hoarseness of voice and neck hematoma. Conclusion: In this study we found higher frequency of hypocalcemia in 25.5% cases after thyroid surgery. Majority of the cases were females and had no retrosternal extension. Except hypocalcemia other complications among all cases were seroma, transient hoarseness of voice and neck hematoma. Keywords: Thyroid Surgery, Tumors, Complications, Hypocalcemia
Use of Drotaverine 80mg with Paracetamol 500mg in Patients with Acute Bacterial Gastroenteristis
Authors: Musanna Syed Hassan , Zaffar Mounis Ahmad , Abdullah M , , Amil Javaria , Saleem Sheraz
Published: July 2022

Objective: This study's goal is to see whether drotaverine 80 mg and paracetamol 500 mg are as effective and safe as each other in treating individuals with acute gastroenteritis. Study Design: Randomized control trial Place and Duration: The study was conducted at the medicine department of Lahore General Hospital and Ittefaq Hospital Trust, Lahore for the period of five months from April 2021 to August 2021. Methods: Total one hundred and eighty patients of both genders with ages 17-60 years were presented. Patients had acute infectious gastroenteritis with abdominal pain from last 24 hours were included. To obtain comprehensive demographic information, including age, gender, height/weight, and BMI (body mass index), informed written permission was obtained from each patient. A total of two groups of patients were created: I and II. It took two days to provide 80mg drotaverine, together with 500 mg paracetamol, to patients in group I, while it took two days to administer 500 mg paracetamol, along with the same number of patients, in group II. A visual analogue scale (VAS) was used to measure the severity of pain in both groups after treatment to determine efficacy and safety. SPSS 24.0 was used to analyze the data. For categorical data, frequency and percentage were employed. Results: Mean age of the patients in group I was 30.07±4.28 years with mean BMI 23.07±4.32 kg/m2 and in group II 28.17±9.88 years was the mean age with mean BMI 22.44±8.21 kg/m2. Majority of the patients were males 59 (65.6%) in group I and 54 (60%) in group II. Intensity of pain was significantly decreases after 8hrs in group I 1.01±2.17 as compared to group II 4.09±11.34. Post treatment effectiveness among patients in group I was 84 (93.3%) greater than that of group II 54 (60%). The most prevalent side effects in both groups were nausea, vomiting, and dizziness, however the frequency was considerably lower in group I than in group II with a p value of 0.005.Frequency of satisfaction in group I was 88 (97.8%) higher than that of group II 60 (66.7%). Conclusion: In this study we concluded that the combination of 80mg drotaverine with 500mg paracetamol was effective and safe in terms of pain control and control of infection as compared to the paracetamol alone in the treatment of patients with acute gastroenteritis. Keywords: Acute Gastroenteritis, Drotaverine, Paracetamol, Efficacy
Combine treatment of Sofosbuvir and Velpatasvir in Patients of Chronic Hapatitis C
Authors: Babur Waseem , Khan Naveed Noor , Javed Syed Meerab , Huma Zille- , Memon Fayaz Ahmed , Azeem Abdul
Published: July 2022

Objective: The purpose of this research is to evaluate how well individuals with chronic hepatitis C respond to a combination treatment consisting of sofosbuvir and velpatasvir. Study Design: Observational/ Prospective study Place of Study: King Salman Armed Forces Hospital Tabuk KSA and Dow University of Health Sciences Karachi Pakistan. Duration of Study: Jan, 2021 to Dec, 2021 Methods: This research included 42 participants of both sexes. Patients ranged in age from 20 to 78. After obtaining written permission, we collected demographic data about the patient, including age, gender, and height and weight. Patients with known genotypes of hepatitis C were presented. Patients were treated for 15 weeks with a SOF/VLP regimen that included sofosbuvir and velpatasvir. SPSS 24.0 version was used to analyse all of the data. Results: There were majority males in this study. The mean age of the cases was 33.8±7.43 years with mean BMI 23.18±7.31 kg/m2. Comorbidities were HTN, DM and obesity among all cases. There were 12 (28.6%) patients had treatment experienced. Frequency of effectiveness was found among 40 (95.2%) cases and 2 (4.8%) patients were died. Post-treatment, we found significantly improvement in aspartate aminotransferase (AST) 36.11 ± 9.13, alanine aminotransferase (ALT) 27.23 ± 11.45 and hemoglobin level 13.8 ± 4.19. Conclusion: The results of this trial led us to the conclusion that the combination therapy of hepatitis C patients with sofosbuvir and velpatasvir was successful, safe, and well tolerated by the patients. Keywords:, Sofosbuvir, Hepatitis C, Velpatasvir, Comorbidities
Prevalence of Hypoglycemia in Patients of Type 2 Diabetes Mellitus
Authors: Javed Syed Meerab , Khan Naveed Noor , Babur Waseem , Memon Fayaz Ahmed , Arshad Ashhar , Huma Zille-
Published: July 2022

Objective: Aim of current study is to evaluate the frequency of hypoglycemia in patients of type-2 diabetes mellitus. Study Design:Cross-sectional Place and Duration: King Salman Armed Forces Hospital Tabuk KSA and Muhammed Medical College & Hospital, Mirpurkhas, Sindh during from June, 2020 to Dec, 2020. Methods: There were 115 patients of both genders had type-2 diabetes mellitus were presented.Patients ranged in age from 20 to 60 years old. Individuals participated in the study were asked to sign a permission form acknowledging they had read the information and understood its significance before having their demographic data collected. Frequency of hypoglycemia was recorded by Whipple’s triad questionnaire based information. Symptoms of hypoglycemia were also recorded. SPSS 23.0 was used to analyze all data. Results:Among 115 patients, majority of the patients 65 (56.5%) were males and 50 (43.5%) were females. Mean age of the patients was 51.6±11.54 years and had mean BMI 27.5±8.34 kg/m2. There were 70 (60.9%) cases had rural residency and 45 (39.1%) patients had urban residency.Most common symptoms were dizziness, weakness and sweating among all cases. Metformin was the most common treatment used among all cases, followed by glynase and insulin. We found frequency of hypoglycemia among 50 (43.5%) in which majority of the cases were females. Among 50 cases of hypoglycemia, 11 cases had severe hypoglycemia, 20 cases had moderate and 19 cases had mild hypoglycemia. Conclusion: In this research, we found that type-2 diabetic patients, most of whom were female and rural, had a high incidence of hypoglycemia. The high incidence requires primary care doctors to ask for hypoglycemia symptoms at each diabetes patient visit. It's also crucial to educate patients about hypoglycemic symptoms and the need of reporting them to alter dosage and avoid recurrence bouts. Keywords:Type 2-diabetes Mellitus, Hypoglycemia, Dizziness, Glynase
Autoimmune hemolytic anemia presenting concurrently with thrombotic thrombocytopenic purpura
Authors: AL-Kadhimi Munaf , Wah Fernanda , AL-Dawoodi Tamarah , Peguero Julio , T Campos Luis
Published: July 2022

Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening syndrome typically characterized by thrombocytopenia and microangiopathic hemolytic anemia (MAHA). Both genetic and idiopathic TTP are caused by deficient activity of the serine protease ADAMTS-13, allowing its normal substrate, von Willebrand factor, to polymerize and bind platelets under high sheer conditions. Autoimmune TTP is typically treated by plasmapheresis and corticosteroids. Here, we describe a 69-year-old patient presenting with thrombopenia comorbid with "warm" autoimmune hemolytic anemia (WAIHA). Treatment with steroids and plasma exchange initiated at the beginning and patient acquired a clinical as well as biological response. Thrombotic thrombocytopenic purpura (TTP) is a life-threatening condition typically (but not always) associated with autoimmune or genetic inactivation of the protease ADAMTS-13, for which consistently effective therapeutic interventions remain elusive.