bluuebunny/crossref_metadata_2025 huggingface dataset:
Sistema electrónico experimental para la medición de variables de parámetros de marcha en ancianos
Authors: Menéndez Álvarez Jaime , Arencibia Castellanos Gianna , Hernández Montero Fidel Ernesto , Rodríguez Suárez Juan R. , Pérez Molinet Ailén
Published: July 2020

En el estudio actual que se realiza en Cuba sobre el monitoreo de indicadores del desempeño físico en ancianos, los parámetros medidos son afectados por la subjetividad del especialista que realiza las mediciones y no se tiene en cuenta la variabilidad que puede existir en estos. Desarrollar y evaluar en un entorno de laboratorio un sistema electrónico, de bajo costo, capaz de medir de forma inalámbrica estas variables físicas brinda la posibilidad de obtener parámetros de la marcha de manera automática. El sistema diseñado está basado en una Unidad de Medición Inercial (IMU) por tanto es capaz de medir la aceleración lineal y la velocidad angular en los tres ejes coordenados, así como la temperatura. El sistema transmite los datos de forma inalámbrica vía Bluetooth hacia una PC donde se implementa la etapa de procesamiento. Se evalúa el sistema de medición diseñado con diferentes pruebas que demuestran un comportamiento satisfactorio. También se muestran los resultados obtenidos al usar el dispositivo, en una prueba de equilibrio dinámico; en la cual las variables físicas obtenidas del IMU son procesadas con el fin de obtener el ángulo de inclinación del sensor.
Partisipasi Pemuda Dalam Meningkatkan Program Wajib Belajar Sembilan Tahun Bagi Masyarakat Kelurahan Denai Kota Medan
Authors: Tambunan Ahmad Taufiq , Revida Erika , Rujiman Rujiman
Published: July 2020

Penelitian ini bertujuan untuk mengetahui partisipasi pemuda dalam meningkatkan program wajib belajar sembilan tahun bagi masyarakat di Kelurahan Denai Kota Medan, disertai dengan kendala-kendala masyarakat dalam menyelesaikan kewajiban menempuh pendidikan selama sembilan tahun, yakni SD dan SMP. Penelitian ini menggunakan jenis penelitian deskriptif dengan pendekatan kualitatif. Informan penelitian ini adalah orang tua yang memiliki anak yang sedang atau telah mengalami masa wajib belajar sembilan tahun dan para pemuda yang tergabung dalam organisasi yang berperan dalam meningkatkan pendidikan wajib belajar sembilan tahun, yang berada di setiap lingkungan di Kelurahan Denai. Hasil yang didapat adalah kendala utama yang dirasakan para orang tua dalam menuntaskan anaknya dalam wajib belajar sembilan tahun adalah dana dan ongkos. Maka peran dan partisipasi pemuda yang tergabung dalam organisasi adalah menjembatani itu. Dari data yang didapat, ada organisasi dengan pemuda yang berada di dalamnya melakukan pencarian orang tua asuh, yang kemudian memberikan bantuan berupa pembebasan biaya uang sekolah bagi anak yatim dan tidak mampu.
The progress of CAR-T therapy in cancer and beyond
Authors: Huang Yehong , Li Lulu , Liu Wenzhou , Tang Tao , Chen Liming
Published: July 2020

Chimeric antigen receptor T (CAR-T) technology is the pinnacle of modern immunology, system biology, synthetic biology and cellular engineering. It is the powerful new player of cancer therapy since the concept of adoptive cell therapy. Clinical success of CAR-T cells targeting antigen unique to B cell leukemia has made it the focus of new development in cancer therapy. The latest success is reported in a clinical case of using CAR-T cells to treat pediatric acute lymphoblastic leukemia. However, the major challenges are to make CAR-T cells a reliable, controllable, safe and effective platform that could apply to diverse cancer types including solid tumors. In this review we summarize the recent research progress to tackle the challenges and discuss the broader application of CAR-T cells beyond cancer in the context of genome editing era.
ON APPROACHES TO THE MANAGEMENT OF CAPITAL FOR SMALL AGRIBUSINESSES
Authors: Smirnova I.Yu. , Vetrova N.M.
Published: July 2020

The article analyzes the features of capital management on the example of OOO «Yarosvit-agro». An analysis of the compliance of the enterprise with the «golden rule» of financing was carried out. Also there was evaluated the compliance of the enterprise with the «golden rule» of financing.
EXPERIMENTAL PARAMETERS FOR BEACH FORMATION IN THE SEASIDE URBANIZED RECREATIONAL TERRITORIES
Authors: Mennanov E.E. , Mennanov E.M.
Published: July 2020

The article presents the results of experimental studies of beach formation in coastal urbanized recreational areasusing coastal protection structures. Two series of experimental studies in the wave basin are considered. The scale of the experimental model is substantiated, and the reliability of the output data on the beach model during experiment No. 1 is confirmed. The effectiveness of the engineering-ecological solution proposed by the author for protecting the beach zone of the coastal urbanized recreational areas according to the results of experiment No. 2 is proved.
RATIONALE FOR USING RECLAIMED STORAGE PONDS TO INCREASE WATER AVAILABILITY WATER-DEFICIENT TERRITORIES OF CRIMEA
Authors: Sadykova G.E. , Ivanenko T.A. , Babchinskaya I.А.
Published: July 2020

In connection with the transition of the Crimean Peninsula to water supply at the expense of its own natural sources, there is a formation of water-deficit conditions in significant territories. The current situation with water scarcity of the territory has a negative impact on all sectors of the national economy. In the current situation, the problem of increasing water availability should be considered comprehensively, taking into account the rational use of water resources and water bodies with the possibility of parallel restoration of disturbed territories. The use of reclaimed storage ponds on local runoff can be a step towards improving the existing water supply system for water-deficient areas.
ФОРМУВАННЯ ІННОВАЦІЙНОЇ СТРАТЕГІЇ УПРАВЛІННЯ ЕКОНОМІЧНОЮ АКТИВНІСТЮ ПІДПРИЄМСТВА ТОРГІВЛІ
Authors: Кащена Н.Б.
Published: July 2020

У статті розглянуто теоретико-методичні засади формування інноваційних стратегій управління економічною активністю підприємств торгівлі. Доведено, що інноваційна стратегія економічної активності торговельних підприємств є стратегією розвитку, орієнтованою на використання інновацій для формування конкурентних переваг високого порядку, підвищення ринкової активності та вартості підприємства в умовах швидкоплинних змін бізнес-середовища та потреб стейкхолдерів. Визначено принципи та розроблено алгоритмічну модель формування й реалізації інноваційної стратегії розвитку економічної активності підприємств торгівлі, яка втілює ключові процеси стратегування (мислення, планування, управління, реалізація, аналіз ситуації та наслідків дій) і дає змогу структурувати порядок дій із розроблення, втілення, контролю виконання та корегування стратегії.
ІНЖИНІРІНГ БІЗНЕС-АРХІТЕКТУРИ ПІДПРИЄМСТВА ДЛЯ ПРОГНОЗУВАННЯ СОЦІАЛЬНО-ЕКОНОМІЧНИХ ПРОЦЕСІВ
Authors: Єсіна О.Г. , Лінгур Л.М.
Published: July 2020

Дослідження присвячено проблемам формування сучасних шаблонів бізнес-архітектури підприємства. Було зазначено, що поява нових бізнес-моделей та адаптивного стилю бізнесу для інжинірингу перехідних моделей повинна базуватися на гнучкому реагуванні на потреби ринку, це динамічний стиль бізнес-архітектури, пов'язаний із визнанням неминучості і непередбачуваності змін у зовнішньому середовищі. Запропоновано концепцію бізнес-архітектури підприємства та загальносистемні проектні рішення на основі автоматизованої підтримки за моделлю SABSA. Прогнозування стану та розвитку соціально-економічних процесів у такій бізнес-архітектурі запропоновано визначити відповідно до концепції (BSC), а моделювання в таких моделях відбувається в інтегрованих ІТ-модулях. Авторами запропонована методика оцінки варіантів вибору альтернатив через багатофакторну модель визначення стану процесів зі встановленими обмеженнями, які визначено як нормативні. На основі сформованої моделі побудована матриця синтезу оптимальних впливів на модель багатофакторного аналізу прогнозування діяльності підприємства на основі системи BSC.
ВИКОРИСТАННЯ ЗАСАД ГЛОБАЛЬНИХ ЦІЛЕЙ СТАЛОГО РОЗВИТКУ ДЛЯ ЗАБЕЗПЕЧЕННЯ РОЗВИТКУ ПРОМИСЛОВОСТІ УКРАЇНИ
Authors: Трофименко О.О. , Дорошкевич Д.В. , Джадан І.М.
Published: July 2020

У статті досліджено основні тенденції розвитку промисловості України. Обрано основні Глобальні цілі сталого розвитку на основі яких має забезпечуватися розвиток промисловості України, а саме: Ціль 8 “Гідна праця та економічне зростання”, Ціль 9 “Інновації й інфраструктура”, Ціль 12 “Відповідальне споживання”, Ціль 17 “Cпівпраця заради досягнення цілей”. Досліджено основні передумови розвитку промисловості. Співставлено динаміку індексів валового внутрішнього продукту та промислової продукції. Визначені основні країни, які доцільно використовувати як орієнтири для аналізу прогресу досягнення цілей сталого розвитку та розвитку промисловості. Наведено динаміку реального ВВП на душу населення в досліджуваних країнах та в Україні. Визначені основні негативні та позитивні аспекти розвитку промисловості на засадах глобальних цілей сталого розвитку. Досліджено окремі показники ефективності заходів щодо досягнення визначених цілей сталого розвитку в Україні.
Perancangan Arsitektur Sistem Informasi Absensi dan Penggajian Menggunakan Framework Zachman
Authors: Sastradipraja Cecep Kurnia , Darmawan Gumgum , Hadi Juandi
Published: July 2020

Penelitian ini bertujuan untuk merancang arsitektur sistem informasi dengan pendekatan model enterprise architecture menggunakan metode Framework Zachman dengan mengadopsi 4 baris (Planner, Owner, Designer, Builder) dan 5 kolom (What, How, Where, Who, When) di PT. XYZ Realty Kabupaten Sukabumi. Teknik dan sumber pengumpulan data adalah melalui proses observasi, wawancara, dan penyebaran angket terhadap pihak-pihak terkait pada PT. XYZ Realty. Hal ini dilakukan berdasarkan hasil temuan yang menunjukan bahwa kondisi saat ini khususnya pada bagian keuangan, dalam pengelolaan absensi dan penggajian karyawan masih menggunakan alat bantu aplikasi Ms. Excel, serta belum terintegrasinya antara data absensi dan data penggajian. Dari penelitian ini menghasilkan prototipe aplikasi dengan hasil analisis dan pengujian korelasi yang menunjukan bahwa penerapan metode Framework Zachman yang diimplementasikan pada sistem informasi absensi dan penggajian berbasis web memilki korelasi yang sangat kuat.
Perancangan Sistem Keamanan Menggunakan Solenoid Door Lock Berbasis Arduino Uno pada Pintu Laboratorium di PT. XYZ
Authors: Suwartika Rini , Sembada Gandang
Published: July 2020

Penelitian ini bertujuan untuk merancang sistem keamanan pintu laboratorium menggunakan keypad dengan solenoid berbasis Arduino Uno di PT. XYZ. Metode penelitian menggunakan metode penelitian dan pengembangan (Research and Development). Metode penelitian dan pengembangan adalah metode penelitian yang digunakan untuk menghasilkan produk tertentu dan menguji efektivitas produk ini. Sehubungan dengan masalah yang dihadapi, teknik pengumpulan data digunakan dengan mengamati dan dilengkapi dengan tinjauan literatur. Permasalahan dalam penelitian yang telah dilakukan adalah tentang keselamatan laboratorium yang membutuhkan sistem keselamatan pintu menggunakan model kode keamanan. Oleh karena itu, desain alat pengaman pintu dibuat dengan selenoid berdasarkan Arduino Uno menggunakan tombol sebagai alat input dan diimplementasikan dengan bahasa pemrograman C. Alat yang dirancang ini diharapkan dapat bermanfaat bagi perusahaan dalam hal keamanan.
ДИСТАНЦІЙНЕ НАВЧАННЯ: РЕАЛІЇ І ПЕРСПЕКТИВИ
Authors: Malovanyi Yurii
Published: July 2020

У статті на підставі даних, здобутих у процесі оперативних досліджень учених Відділення загальної середньої освіти НАПН України, виокремлено основні проблеми в організації і здійсненні навчання учнів закладів загальної середньої освіти в онлайн-режимі під час масового короновірусного карантину. Серед них — відсутність якісного інтернет зв'язку, неповне забезпечення суб'єктів освітнього процесу необхідними гаджетами для його ефективного здійснення, відсутність належного попереднього досвіду роботи в умовах дистанційного навчання, недостатня методична підготовленість педагогів до такого виду навчання та ін. Окреслено пріоритетні напрями удосконалення й розвитку дистанційного навчання. Висловлено застереження щодо абсолютизації можливостей дистанційного навчання і перспективи утвердження його як єдиного панівного виду навчання в освітньому просторі країни.
Effect of magnetic field, heat generation and absorption on nanofluid flow over a nonlinear stretching sheet
Authors: Misra Santoshi , Kamatam Govardhan
Published: July 2020

The study of magnetohydrodynamic flow of a nanoparticle suspension under the influence of varied dimensionless parameters has been the focus of research in contemporary times. This work models the effect of magnetic field, heat generation and absorption parameter in a steady, laminar, two-dimensional boundary layer flow of a nanofluid over a permeable stretching sheet at a given surface temperature and partial slip. The highly nonlinear governing equations are solved numerically using similarity transformations with suitable boundary conditions and converted to ordinary differential equations. A computational model is setup using FORTRAN, where a relevant Adam’s predictor–corrector method is employed to solve the equations. The impact of the dimensionless parameters, including the Brownian motion, thermophoresis, magnetic field, heat generation and absorption parameters, on the velocity, temperature and nanoparticle concentration of fluid flow are analysed systematically.
A dynamic combinatorial library for biomimetic recognition of dipeptides in water
Authors: Klepel Florian , Ravoo Bart Jan
Published: July 2020

Small peptides are involved in countless biological processes. Hence selective binding motifs for peptides can be powerful tools for labeling or inhibition. Finding those binding motifs, especially in water which competes for intermolecular H-bonds, poses an enormous challenge. A dynamic combinatorial library can be a powerful method to overcome this issue. We previously reported artificial receptors emerging form a dynamic combinatorial library of peptide building blocks. In this study we aimed to broaden this scope towards recognition of small peptides. Employing CXC peptide building blocks, we found that cyclic dimers of oxidized CFC bind to the aromatic peptides FF and YY (K ≈ 229–702 M−1), while AA binds significantly weaker (K ≈ 65–71 M−1).
LIPID NANOPARTICLES FOR THE TRANSPORT OF DRUGS LIKE DOPAMINE THROUGH THE BLOOD–BRAIN BARRIER
Authors: Ortega Elena , Blanco Santos , Ruiz Adolfina , Peinado María Ángeles , Peralta Sebastian , Morales María Encarnación
Published: July 2020

Diseases and disorders of the nervous system, like Parkinson disease (PD) and others neurodegenerative pathologies are widespread in our society. The arsenal of treatments against these pathologies continues to increase, but in many cases its use is limited. This is due to the blood-brain barrier (BBB), which acts by limiting the penetration of drugs into the brain. To overcome this handicap, in the current research solid lipid nanoparticles (SLNPs) able to encapsulate drugs and to cross the blood-brain barrier have been designed to transport and release these drugs into their targets. These SLNPs were synthesized by a sonication method and high agitation process searching the most adequate physicochemical profile to achieve the objectives set. Today, the most efficient treatment for PD consists of providing the dopamine (DP) that is lost by neurodegeneration; however, the nature of this neurotransmitter prevents its crossing of the BBB. Therefore, DP may be considered as a good candidate to be encapsulated in SLNPs while studying how the loading drug could affect such nanoparticles. Based on these antecedents, in this research, both empty and DP-charged SLNPs were characterized physicochemically. The results obtained indicated a great stability of the nanoparticles loaded with DP when drug was used at 0.2 to 0.05%; these concentrations barely affected its size, polydispersity and ζ-potential, and the SLNPs elaborated in this research were high appropriate to be injected systemically. Finally, empty SLNPs labeled and administered systemically to adult male Wistar rats demonstrate their penetration ability into the brain parenchyma.
PESANTREN DAN PENANAMAN SIKAP ANTI KORUPSI
Authors: Fathoni Tamrin
Published: July 2020

The purpose of this study is to explore the role of pesantren in instilling anti-corruption attitudes. Pesantren is empirically known as a successful institution in developing quality education, especially in the field of religion. In the midst of a number of compliments received from pesantren, there is criticism that must reflect the pesantren, that pesantren are considered to have not succeeded in perfectly educating students who have strong personalities in anti-corruption. That criticism is not without foundation. The ministry of religion which incidentally is the headquarters of the students, is also known as one of the ministries which often ministers stumble over corruption cases. Even though they are not a few who in their daily lives work as preachers and obligatory worshipers, and can even be categorized as scholars. This study uses qualitative research library type. Data collection by identifying discourses from books, papers or articles, journals, newspapers, internet (websites), and other information that is still related to pesantren studies. Data analysis uses descriptive analysis and critical analysis. Descriptive analysis is collecting and compiling data then the data is analyzed. Meanwhile, critical analysis is the interpretation of the text and addressing the meaning behind events scientifically. The results showed the need for pesantren stakeholders to reaffirm the pesantren culture to instill anti-corruption in their students. especially through his students. Because students with their pesanten culture (a) have a simple tradition of life an absolute requirement to be a pioneer of anti-corruption; (b) has strong religious insight, and (c) deep-rooted tradition amar ma'ruf nahi munkar.
GROWTH AND DEVELOPMENT OF AGATE INDUSTRY IN GUJARAT –A CASE STUDY OF KHAMBHAT
Authors: Patel Mahesh , Rangiya J. G.
Published: July 2020

The paper looks at the growth and development of agate industry in the Khambhat area of Gujarat, India. The data collected for the understanding had use mix methodology which is explained in the paper below. The paper tries to understand the current situation of the agate industry in context of history, economics, environment and labourers (workers). The paper also explains the basic of agate and the manufacturing process that is used in the agate industry. And at the end the paper provides the readers with the current scenario of the agate industry in Khambhat area of Gujarat.
Perspetiva do Enfermeiro em relação à Via Verde Trauma
Authors: Almeida Ana , Ribeiro Carlos , Paes Pedro , Mota Liliana , Príncipe Fernanda
Published: July 2020

Enquadramento: De acordo com a Organização Mundial de Saúde (OMS), o trauma é um dos maiores problemas de saúde a nível mundial sendo responsável por um aumento da mortalidade e morbilidade da população. Ao reconhecermos os Enfermeiros como atores importantes na abordagem à vítima de trauma consideramos pertinente conhecer a sua perspetiva em relação à Via Verde Trauma (VVT) uma vez que esta é uma medida considerada relevante positivamente para a melhoria do atendimento ao Utente vítima de trauma. Objetivo: Com a realização deste trabalho pretende-se identificar as dificuldades de implementação da VVT e os ganhos em saúde que esta Via Verde (VV) traz na perspetiva do Enfermeiro e refletir acerca dos motivos da baixa implementação desta VV. Metodologia: Estudo qualitativo, exploratório com recurso a focus groups (FC)como método de recolha de dados. Amostra não probabilística, análise de dados de acordo com o método de análise de conteúdo de Bardin. Resultados: Após análise das transcrições surgiram três categorias: Identificação de vantagens, necessidades formativas e identificação de fatores barreira que evidenciam a perspetiva do Enfermeiro acerca da VVT. Conclusão: Os enfermeiros consideram a VVT uma ferramenta que acarreta vantagens importantes a nível dos cuidados à pessoa vítima de trauma, reconhecendo as necessidades formativas e fatores barreira que possam existir.
Briefing na prática simulada: representação para os estudantes e docentes
Authors: Novais Sónia , Alves Maria , Pinho Ana , Baltarejo Viviana
Published: July 2020

Enquadramento: a prática simulada é uma estratégia pedagógica que estimula a tomada de decisão em casos clínicos. A sua implementação decorre por etapas, sendo o briefing a primeira. Objetivo: compreender a representação do briefing para os estudantes e docentes envolvidos nas aulas de prática simulada do curso de licenciatura em Enfermagem. Metodologia: estudo qualitativo e descritivo orientado pela teoria das representações sociais. Participaram 37 estudantes do curso de Licenciatura em Enfermagem, que se encontravam inscritos em unidades curriculares que recorriam à metodologia de prática simulada e os 7 docentes das mesmas unidades curriculares. A recolha de dados foi realizada através de um questionário que continha um Teste de Associação Livre de Palavras. A analise de dados foi realizada através do software IRAMUTEQ. Resultados: os estudantes representam o briefing valorizando o domínio cognitivo, mas salientando igualmente o domínio afetivo. Os docentes valorizam a preparação dos cenários com o objetivo de alargar o horizonte dos estudantes, procurando aumentar o conhecimento e a experiência através do estabelecimento de objetivos de aprendizagem. Conclusão: considerando os objetivos da prática simulada, o briefing é representado como uma etapa promotora do conhecimento, das aprendizagens e das competências, mas também gerador de emoções.
COVimpact: pandemia COVID-19 nos estudantes do ensino superior da saúde
Authors: Ferreira António Manuel dos Santos , Principe Fernanda , Pereira Henrique , Oliveira Isabel , Mota Liliana
Published: July 2020

Enquadramento: no contexto de emergência de saúde pública internacional por SARS-CoV-2, a suspensão das atividades letivas presenciais criou uma disrupção ao regular funcionamento das instituições de ensino superior com impacte na comunidade académica. Objetivo: avaliar o impacte da pandemia COVID-19 no percurso académico e de vida dos estudantes e sua satisfação com as medidas adotadas. Metodologia: estudo descritivo, exploratório. Recolha de dados por questionário online, com questões centradas nas condições para o ensino à distância, nas vivências dos estudantes e no impacte e satisfação com o Plano de Contingência. A amostra não probabilística e de conveniência. Análise estatística dos dados de acordo com a natureza das variáveis. Resultados: participaram 264 estudantes com idade média de 28,2±10,2 anos. No geral, referem muito boas condições em casa para concretização do ensino à distância (X=4,4±0,67,2−5). A maioria (79,2%, n=209) refere ter participado nas atividades não presenciais após a ativação do Plano de Contingência. Da análise do impacte verificam-se níveis de adequação muito elevados das plataformas educativas. Constata-se também, uma elevada satisfação com a informação fornecida. Conclusão: as medidas adotadas foram adequadas tendo contribuído para reduzir o impacte do COVID-19 no processo de ensino, aprendizagem e avaliação dos estudantes.
Responsabilidade médica e prescrição off-label de medicamentos no tratamento da COVID-19
Authors: Soares Flaviana Rampazzo , Dadalto Luciana
Published: July 2020

Este artigo tem a finalidade de investigar responsabilidade médica na prescrição off-label de medicamentos para o tratamento de pacientes infectados pelo coronavírus. A análise desse tema passa, em sua trajetória investigativa, pela exploração conceitual da prescrição off-label, os limites dessa prescrição e a fronteira entre a licitude e a ilicitude nessa conduta, a verificar se existe diferenciação na responsabilidade por prescrição off-label em situação de pandemia e fora desta, no que concerne às suas consequências jurídicas no campo do direito de danos. Cuida-se de tema cuja atualidade e importância é acentuada nesse período excepcional de pandemia, cuja repercussão ainda será sentida nos Tribunais, em demandas indenizatórias que possam ser propostas por pacientes que tenham sofrido danos   por experimentarem efeitos colaterais provenientes de uma administração medicamentosa baseada em uma prescrição médica dessa natureza. Buscar-se-á igualmente apontar, no decorrer do texto, alguns dos diversos desafios a serem enfrentados, bem como as suas admissíveis soluções, as quais necessariamente passam pela indicação de alguns requisitos que podem ser aceitos como de justificação à prescrição off-label, para que seja possível identificar quando a conduta médica poderá ser considerada lícita ou ilícita.
Teoría administrativa y fuerza militar: Un análisis de los principales aportes de las teorías clásicas de la administración a la gestión en las fuerzas militares
Authors: Ortiz-Bethés Carlos Ernesto
Published: July 2020

La práctica de la administración de la primera mitad el siglo XX junto con su teorización se ha visto enmarcada a la luz de tres paradigmas administrativos: El paradigma tecno-ingenieril, el paradigma sociológico y el paradigma humanista psicológico que han dado a luz las teorías clásicas de la Administración como son La Administración Científica de Taylor, La Administración Clásica de Fayol, La Teoría de las Relaciones Humanas de Mayo y La Burocracia de Weber, todas con un marco conceptual distintivo que han apuntado a la solución de los problemas organizacionales de las empresas en sus respectivos contextos históricos y que aún siguen siendo de gran utilidad, no solamente a las empresas privadas, sino también a las organizaciones estatales. De ahí que surge el análisis de este documento que presenta las principales aportaciones de las teorías clásicas de la administración de la primera mitad del siglo XX a la gestión de las fuerzas militares entorno a tres tópicos: Las tareas, las interacciones sociales y las relaciones de poder en las estructuras de orden jerárquico.
Retos logísticos de puertos de cuarta generación diagnóstico y modernización en países emergentes
Authors: Boyano-Fram Teófilo Omar
Published: July 2020

Así como los Sistemas de Información y los buques o embarcaciones se van perfeccionando y facilitando la atención a los usuarios, de nada sirve si el Puerto como un todo, no está preparado para atender las exigencias del Mercado. El siguiente texto es el resultado de una revisión de la literatura relacionada con el tema, en el que se describe los Referentes relacionados con Puertos de Cuarta Generación, además se incluye los retos que tendrán que enfrentar en un país que no logra tener índices de Desarrollo Económico, en él se infere que políticas públicas orientadas a fortalecer el Puerto a la altura de los más desarrollados será el camino de entrar en Puertos de Cuarta Generación.
La minería criminal en el río Atabapo frontera colombo venezolana: propuestas de solución
Authors: Fonseca-Moreno Andrea Catalina , Gualteros-Pinzón Carlos Edgardo , González-Díaz Jaime Eduardo
Published: July 2020

El propósito de este artículo es describir el fenómeno de la minería criminal en el río Atabapo límite territorial con Venezuela, y presentar propuestas de solución a este fenómeno. Este es producto de una investigación descriptiva. Presenta un diagnóstico de los aspectos inﬂuyentes en el ámbito económico, social, político y militar; y los efectos de estos a futuro de no generarse o contar con una política que permita regular tal actividad. En el aspecto económico los pobladores mayoritariamente indígenas han cambiado la forma de sustentarse debido a la generación de empleo directo por parte de grupos que desarrollan actividades de minería criminal, así también como la afectación de esta actividad en el tema de regalías. En el aspecto social es importante atender la afectación a mediano y largo plazo de la salud de la población de los dos países generada por el vertimiento de elementos como mercurio y cianuro. En el aspecto político, el desconocimiento de la población del área referente a la normatividad minera, la afectación de la soberanía de los dos países dada por la inﬂuencia del hombre en el lecho del río. En el ámbito militar actualmente en área y en general en esta parte de la frontera se encuentran grupos al margen de la ley que se ubican estratégicamente en la frontera Colombo-Venezolana con el objetivo de consolidar corredores tácticos de movilidad.
Calidad en la educación universitaria, desde el programa de ingeniería de sistemas: una visión cualitativa de la educación superior
Authors: Ramírez-Fernández René , Machado-Licona Jhorquis , Fernández-Ramírez Oscar Eduardo
Published: July 2020

El presente documento divulga los resultados de la investigación “calidad en la educación universitaria, percepción de los estudiantes de la facultad de ingeniería” realizada en el programa de ingeniería de sistemas de una Universidad de la Ciudad de Cartagena; el objetivo de dicha investigación es analizar como los estudiantes del programa de ingeniería de sistemas observan la calidad de educación impartida en la Universidad; para el estudio se seleccionaron cuatro variables, currículo, formación docente, soporte administrativo e infraestructura, las cuales fueron evaluadas por los alumnos de segundo a decimo semestre; el método implementado es deductivo-inductivo y el enfoque es cualitativo. Dentro de los principales resultados, se pudo observar que las unidades de análisis, actualidad del currículo, tutorías y refuerzos, adecuación de las aulas y espacios de socialización, son lo que demandan mayor trabajo por parte de la Universidad.
Time Dependent Ca2+ Induction Led to the Formation of Mitochondrial Permeability Transition Pore as a Function of Age
Authors: Kumar BS Mohan , Basha P Mahaboob
Published: July 2020

Ca2+ sequestration and its homeostasis is disrupted when mitochondrial membrane permeabilises to form a large opening - the mitochondrial permeability transition pore (MPTP). The MPTP formation is common during aging and age related pathologies, activating cell death pathways to avoid unhealthy consequences and malignancies in the brain tissue. Several studies have identified the participation of Cyclophilin-D (Cyp-D) and adenine nucleotide translocase(ANT) in forming MPTP. However, Ca2+ is known to participate significantly in MPTP induction, although its concentration and time dependent permeabilization mechanisms are still elusive. In this work, we have focused on the contribution of Ca2+ participation, its concentration and time taken to permeabilze the mitochondrial inner membrane as a measure of light scattering at 540 ηM. We have observed that MPTP formation is increased in mitochondria isolated from aged rats in comparison to young adult and neonatal rats. The cyclosporin A application blocks the cyclophilin interaction thus avoiding MPTP formation confirming the crucial role of Ca2+ inducted MPTP opening. A 100 µM Ca2+ incubation for 15 minutes allowed the 50% probability of formation of MPTP in mitochondria isolated from all age groups. Thus, alleviating its role in aging and neurodegeneration.
Technology Innovation Transition Strategy to Achieve Indonesian Local Millennial Customer Satisfaction in Using Digital Facilities
Authors: Marina Debby Christyna , Mulyana Ahmad
Published: July 2020

This study aims to analyze how the use of digital facilities as a form of transition to technological innovation for Indonesia's local millennial. Technology Innovation Transition is an action to change the old work system to a new work system, starting from the conventional one to more sophisticated technology. In this context, the transition of technological innovation has become part of the customer service industry, one of the biggest users of digital facilities is local millennial, in this study the researchers narrowed the scope of millennial discussion, researchers focused more on Indonesian local millennial. The theory used to analyze is the theory of innovation and other supporting theories. This study uses a qualitative method with a case study approach and data collection techniques by means of in-depth interviews with informants and field observations to answer the results of the research. The results of the study show that certain levels of local Indonesian millennial capabilities have not really been able to fully adapt to sophisticated technological innovations as a form of transition.
Characteristics of Transcendental Leadership in Managing Eductional Organization to Sustainable
Authors: P Srichaiwong. , P Jedaman. , S Teemueangsa. , K Wongsa-ard. , B ongmuanwai. , P Darae.
Published: July 2020

Leadership is important characteristics of leaders to will be implemented in managing organization to effectiveness. Specific purpose this study have the objectives are to analyzed characteristics of transcendental leadership in managing educational organization to sustainable, and analyzed relationship of characteristics of transcendental leadership for effecting job satisfaction and organization commitment. Collections of qualitative research came from documentary study and interview, quantitative to survey by questionnaire into the data. Characteristics of transcendental leadership including leadership spirit, vision, morals and ethics, pursuing service, leader competency. Relationship of characteristics of transcendental leadership with job satisfaction and organization commitment to positive relations of statistical significance at the level of .01. Finally, leadership were special skills into ability of energetic and ability of creating passionate for personnel in all sectors.
A Study to Assess the Knowledge Regarding Occupational Hazards and Utilization of Safety Measures among Construction Labourers at Selected Construction Sites of Jodhpur
Authors: Soni Mukesh , Khan Parvej
Published: July 2020

Work plays an important role in people's lives as most workers spend at least 8 hours a day in the workplace whether it be in a building, office or factory. Occupational health is also a health concern regarding work and work. Occupational health not only protects health but also promotes health, emergency care, a wide range of preventative, therapeutic, rehabilitation services, an all-encompassing concept that can work to promote the health and wellbeing of employees. Construction work is considered a physically demanding task, usually under difficult conditions including hot, cold or wet weather. Construction workers closest to immigrants and members of other low-income groups are dealing with illness and injury resulting from work. Quantitative descriptive survey study approach and non experimental research design was used.Total 50 construction labourers working in construction site Jodhpur were selected by purposive sampling technique.Data collection by structured knowledge questionnaire and analysed by using descriptive and inferential statistics.
THE CONDITIONS OF THE PRC’S HIGH-TECHNOLOGICAL ENTERPRISES DEVELOPMENT
Authors: Pinegina I. T. , Lee Haotian
Published: July 2020

The article discusses the conditions for the development of high-tech enterprises of the PRC, notes the development programs of China's innovation sphere, and highlights the strategic changes in the state management of the economy.
Preclinical study of innovative peptides mimicking the tertiary structure of the α-helix B of erythropoietin
Authors: Golubev Ivan V. , Gureev Vladimir V. , Korokin Mikhail V. , Zatolokina Maria A. , Avdeeva Elena V. , Gureeva Anastasia V. , Rozhkov Il’ya S. , Serdyuk Elena A. , Soldatova Valeriya A.
Published: July 2020

Introduction: The aim of this study was to examine the effectiveness of innovative peptides obtained by addition of polypeptide motifs with antiaggregation activity (Arg-Gly-Asp, Lys-Gly-Asp and Pro-Gly-Pro) to a peptide mimicking the tertiary structure of the α-helix B of erythropoietin pHBSP (Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser).

Materials and methods: The cytoprotective activity of innovative peptides mimicking the tertiary structure of the α-helix B of erythropoietin at the doses of 5 μg/ml, 30 μg/ml and 50 μg/ml was studied on human endothelial cell cul­ture in a simulated oxidative stress. An ADMA-like model of preeclampsia was simulated in the experiment. The study was conducted in 260 female Wistar rats, weighing 250–300 g.

Results and discussion: Innovative peptides mimicking the tertiary structure of the α-helix B of erythropoietin retain their cytoprotective activity in a simulated oxidative stress in HUVEC cell culture at the doses of 5 μg/ml, 30 μg/ml, and 50 μg/ml. The compounds with laboratory codes P-αB1 and P-αB3 had the most pronounced cytoprotective activity. Administration of N-nitro-L-arginine-methyl ether to pregnant females for 7 days causes the morphofunctional changes similar to clinical changes in preeclampsia. The innovative peptide under laboratory code P-αB4 at the dose of 50 μg/kg mimicking the tertiary structure of the α-helix B of erythropoietin shows the most pronounced protective properties.

Conclusion: Innovative peptides mimicking the tertiary structure of the α-helix B of erythropoietin have a pronounced positive influence on the morphofunctional disorders in animals with ADMA-like preeclampsia.
Contestation et apprentissage, ou l’entrée en citoyenneté des ouvriers immigrés (Talbot-Citroën, 1982-1983)
Authors: Gay Vincent
Published: July 2020

Au début des années 1980, les ouvriers immigrés de plusieurs usines automobiles de la région parisienne entament de longs mouvements de grève. Cette conflictualité s’inscrit dans un moment particulier de redéfinition de la citoyenneté industrielle ; alors que celle-ci a été bridée pendant de longues années par des systèmes de relations sociales autoritaires, la citoyenneté des ouvriers immigrés trouve à se déployer sous différentes modalités, plus ou moins agonistiques. La participation aux élections de représentants du personnel permet une première entrée en citoyenneté, puis celle-ci est prolongée par la grève, par une contestation quotidienne et enfin par un investissement syndical. Les pratiques des ouvriers immigrés ainsi que les modalités de leur représentation collective donnent dès lors une nouvelle dimension à la citoyenneté industrielle.
Combattantes, terroristes ou victimes ?
Authors: Boutron Camille , Le Basque Myriam
Published: July 2020

Cet article analyse l’engagement des femmes dans la violence politique dans le cadre de la lutte antiterroriste. À partir d’une perspective transdisciplinaire croisant la sociologie et le droit, il interroge l’évolution des perceptions et du traitement juridique de cet engagement, en montrant que celui-ci constitue un reflet des nouvelles formes de conflictualités. Les femmes sont restées traditionnellement en marge des études sur la guerre et la conflictualité. Or, bien qu’elles aient activement participé aux luttes de libération nationales qui émergent dans de nombreux pays dans la seconde moitié du siècle, c’est avant tout en tant que victimes qu’elles vont se rendre visibles sur la scène internationale. Les attentats du 11 septembre 2001 marquent une rupture, alors qu’à la doctrine de « contre-insurrection » qui dominait jusqu’aux années 1970 se substitue celle de « guerre globale contre le terrorisme ». Dans un tel contexte, la violence féminine est considérée comme une illustration de la menace terroriste. L’image de la femme terroriste vient dès lors contester celle de la combattante héroïque ou de la victime courageuse. Ce glissement dans les représentations produit des impacts concrets tant dans la société que dans le champ juridique.
Tehnični problemi in naključja kot botri uspeha
Authors: J. Żuchowski Tadeusz
Published: July 2020

Poznanjska jezuitska cerkev je bila zgrajena v več fazah med letoma 1651 in 1701 po načrtih arhitektov Tomassa Poncina, Bartłomieja Nataniela Wąsowskega in Giovan- nija Catenazzija. Gradnja se je močno zavlekla zaradi Poncinoviih začetnih tehničnih napak (med letoma 1651 in 1653) in poskusov njegovih naslednikov, da bi jih odpravili. Zanimiva končna rešitev notranjščine cer- kve je splet naključij. Mogočni stebri naj bi po prvotnem načrtu Wąsowskega podpirali obok s prečnimi loki, ki ga zaradi pomanjanja tehnološkega znanja nad tako široko ladijo niso uresničili; ladja je pokrita z lesenim stropom, ki posnema banjasti obok. Stebri, postavljeni za nerealizirani obok, so ostali in dali notranjščini edin- stven karakter. Zamisel o stebrih je predstavljala izhodi- šče za nadaljno gradnjo, ki jo je med leta 1696 prevzel in do leta 1701 zaključil Catenazzi.
Bratovščine v klariških samostanih na Kranjskem
Authors: Lavrič Ana
Published: July 2020

Prispevek se osredotoča na novoveške bratovščine, ki so delovale pri samostanih klaris na Kranjskem do njihove ukinitve pod Jožefom II. in so bile doslej v strokovni literaturi obravnavane predvsem z zgodovinskega vidika. Z bratovščinama v Ljubljani (1702) in Mekinjah (1717–1718) so klarise na Kranjskem spodbudile češčenje Jezusovega in Marijinega Srca, škofjeloške bratovščine (1717, 1725–1726, 1775–1776) pa so pospeševale v deželi že vkoreninjene pobožnosti do Marijinega brez- madežnega spočetja, sv. Jožefa (sv. Družine) in Imena Jezusovega. Umetnostna dediščina klariških bratovščin je razmeroma skromna, povezana z usodo posameznih samostanov po njihovi ukinitvi, in tudi po kakovosti posebej ne izstopa, zanimiva pa je po ikonografiji z bogato simboliko srca. Zaradi narave ohranjenega gradiva ima prispevek različne vsebinske poudarke in težišča.
Najzgodnejše omembe umetnikov v slovenskem jeziku
Authors: Golec Boris
Published: July 2020

Prispevek obravnava najzgodnejše omembe slikarjev, kiparjev in drugih umetnikov v slovenskem jeziku. Glede na to, da je bila pisana slovenščina v svetni sferi do razsvetljenstva zelo malo rabljen jezik, srečamo večje število tovrstnih omemb šele sredi 18. stoletja. Slovenski nazivi za njihove poklice so sicer v slovenskih besedilih in slovarjih izpričani od druge polovice 16. stoletja, vendar brez navezave na konkretne osebe. Dragocen vir omemb predstavlja obsežna oklicna knjiga ljubljanske stolne župnije sv. Nikolaja iz let 1737–1759. Slovensko izrazje za obravnavane poklice, ki ga v njej srečujemo, je bilo v celoti adaptirano iz nemščine. Slikarji so označeni kot malar in maler, kiparji kor pilavar, pildtaver in bildtaver, slikarji kart kot kartenmalar oziroma kartenmaler, pozlatarji kot faser in fergulder oziroma ferguldar, edini stavbenik pa kot paumaster. Knjiga ni samo bogat vir podatkov slovenske poklicne terminologije 18. stoletja, ampak tudi zakladnica za preučevanje mikrokozmosa posameznikov.
Mnoge sledi bratovščine sv. Mihaela v Mengšu pri nastanku poslikav Franca Jelovška
Authors: Žnidaršič Golec Lilijana
Published: July 2020

Prispevek na podlagi gradiva duhovniške bratovščine sv. Mihaela v Mengšu (še zlasti seznama članov), objavljenega v Zgodovinskem zborniku, Prilogi časopisa Laibacher Dioecesanblatt v letih 1892–1895, in drugih primarnih virov ali nanje oprtih študij odkriva povezave bratovščinskih članov in podpornikov z deli v Mengšu rojenega slikarja Franca Jelovška (1700–1764). Kot izhodišče je izpostavljeno dejstvo, da se je v času Jelovškove formacije, leta 1722, bratovščini (duhovno) pridružil njegov oče, mengeški organist in cerkovnik Andrej Jelovšek. Zbrani podatki razkrivajo imena ter sorodstvene in druge vezi tistih duhovniških članov in laiških podpornikov bratovščine, ki so kot naročniki ali (so)priporočitelji vplivali na nastanek velikega dela Jelovškovih baročnih stvaritev, med katerimi se nekatere niso ohranile in jih poznamo le posredno. Ob tem je treba upoštevati, da je k naročilom nemalo pripomogel Jelovškov sloves, kar velja zlasti za čas od srede tridesetih let 18. stoletja.
Janez Ernest II. grof Herberstein in naročila opreme za župnijsko cerkev sv. Lenarta v Slovenskih goricah
Authors: Košak Tina
Published: July 2020

Prispevek na podlagi temeljite analize računskih knjig župnije Lenart v Slovenskih goricah in njihovih prilog obravnava naročila opreme, ki jo je Janez Ernest II. grof Herberstein (1709–1780) v drugi polovici 18. stoletja pridobil za lenarško župnijsko cerkev. Vrsta zanesljivih novih atribucij in datacij predstavlja temelj nadaljnjemu raziskovanju grofovih naročil v njegovih rezidencah. Herberstein je opremo naročal pri privilegiranih umetnikih iz deželne prestolnice, pri kiparju Johannesu Piringerju (1709–1788) ter slikarjih Johannu Baptistu Antonu Raunacherju (1729–1771) in Antonu Jantlu (1723–1805). Vsi omenjeni umetniki so sodelovali pri prenovah v dvorcu Eggenberg in graški palači, rezidencah Karla Leopolda grofa Herbersteina in njegove žene Marije Eleonore, roj. kneginje Eggenberg.
Plečnikova cerkev sv. Antona Padovanskega v Beogradu
Authors: Prelovšek Damjan
Published: July 2020

Članek prinaša nove ugotovitve o gradnji in opremljanju Plečnikove beograjske cerkve sv. Antona, ki temeljijo na doslej neupoštevanem arhivskem materialu iz Beograda in Jajca. Po tem, ko je novi provincial fra Josip Markušić zavrnil umetniško nedozorel načrt cerkve, so se beograjski frančiškani obrnili na Plečnika. Ta jim je narisal podolgovato cerkev s širokim zvonikom, kakršno so tedaj po njegovih načrtih gradili v Pragi. Kot alternativo jim je ponudil tudi cenejšo okroglo varianto z visokim zvonikom, ki so jo z veseljem sprejeli. Ker ni zaupal lokalnim izvajalcem in bi gradnja presegla finančne možnosti frančiškanov, je opustil sprva zamišljeno kupolo. Na Plečnikovo željo so se frančiškani odločili za dražjo vidno opeko. Cerkev so med letoma 1929 in 1932, to je v času najhujše gospodarske krize, gradili madžarski zidarji iz Vojvodine. Pri ikonografskem programu je Plečnik sodeloval z Markušićem in leta 1936 izdelal generalni predlog opreme. Po letu 1945 se je z dokončanjem cerkve ukvarjal agilni župnik fra Eduard Žilić. Plečnik je za svojega naslednika predlagal arhitekta Janeza Valentinčiča, ki je med drugim dozidal vhodno lopo in zvonik. Pri slednjem je, da bi nekoliko razbremenil temelje, uporabil železobetonsko jedro, navzven pa ga je oblekel z vidno opeko.