bluuebunny/crossref_metadata_2025 huggingface dataset:
The Phytochemical and Biological Activities of Two Phyllanthus Species: Insights into Metabolit, Antioxidant and Antibacterial Activity
Authors: Araújo Otilda Fátima , Kristiani Elizabeth Betty Elok , Kasmiyati Sri , Nugroho Laurentius Hartanto
Published: December 2024

Phylanthus species, including P. niruri and P. urinaria have pharmacological potential due to their rich phytochemical composition. People usually used this plant for medicinal treatments. This study aimed to compare the phytochemical and antioxidant and antibacterial activities of two Phyllanthus species. The whole of plants was extracted using maceration method with ethanol as solvent. Phytochemical content analyzed using spectrophotometer.  The reagent used for each compounds that were Folin-ciocalteu for phenolics, AlCl3 for flavonoid, dimethyl sulfoxide for chlorophyll and carotenoid. Bioactivity analysis using 1,1-diphenyl-2-picrylhydrazyl method for antioxidant activity and Kirby-Bauer method for antibacterial activity. The highest flavonoid content (12.22 mg QE/gram extract) and total chlorophyll (43.2 µg/ml extract) in P. niruri while phenolic content (80.8 mg GAE/gram extract) in P. urinaria. The carotene of both Phyllanthus were similar (11.9 µg/ml extract. The IC50 values of P. urinaria (6.16 ± 0.42 μg/ml) and P. niruri (17.72 ± 0.80 μg/ml), which indicated very strong antioxidant activity. P. urinaria leaf extract had stronger inhibition against Escherichia coli than Staphylococcus aureus (>20 mm) and P. niruri leaf extract could inhibit E. coli and S. aureus bacteria at all concentrations (11-20 mm). This study found that phenolic compounds strongly influenced the antioxidant and antibacterial abilities of Phyllanthus, while chlorophyll and carotenoids had only a slight influence. These findings open up opportunities to utilize P. niruri and P. urinaria as antioxidant and antibacterial agents.
Evaluation of Lactic Acid Bacteria and Total Bacterial Load in Milk from Clinical Mastitis, Subclinical Mastitis and Healthy Cows
Authors: Yalcin Semiha , Simsir Mehmet , Kurtulus Eda Merve
Published: December 2024

Aim: Studies on alternative preventive and therapeutic approaches for bovine mastitis have gained momentum in the veterinary field due to bacterial antibiotic resistance. In this study; It was aimed to determine the total bacterial counts and lactic acid bacteria counts in milk taken from lactating cows, clinical/subclinical mastitis and healthy udder lobes, compare them with the results of the California Mastitis Test, used a screening test, and determine the variability of lactic flora load in the cases. Materials and Methods: The milk samples were collected from lactating cows from fifteen farms. Udder quarters were categorized into three subgroups: non-mastitis (NM; n=35), clinical mastitis (CM; n=30), and subclinical mastitis (SCM; n=31). Total bacteria and lactic acid bacteria were counted by inoculating milk samples onto MRS (De Man Rogosa Sharpe Agar), M17 agar and PCA (Plate Count Agar) media. Results: No significant difference between the three groups regarding the logarithmic averages of MRS and M17 colony numbers were found. When evaluated using MRS and M17, no significant difference existed among the NM, SCM, and CM groups (P=0.093). Positive correlations (P=0.001) existed between the mean of PCA, CMT, MRS and M17 media. Conclusion: The total bacterial count in milk, as well as the LAB load, are affected by the growing environment and environmental conditions. The milk microbiota is altered in healthy udder quarters and clinical and subclinical mastitis cases. Further investigation is needed to understand the flora characteristics of milk in cases of bovine mastitis and healthy animals.
Surgical Treatment of Squamous Cell Carcinoma (SCC) of the Third Eyelid in a Cat
Authors: Zamirbekova Nuriza , Satici Iremsu , Pulat Selman , Cifci Aysenur Tural , Kul Mustafa , Alkan Fahrettin , Gungor Rumeysa
Published: December 2024

Squamous cell carcinoma (SCC) is the most common malignant tumor of the eyelid in cats. It is usually seen in white-haired cats aged 10 years and older. Although various regional and systemic chemotherapy treatments have been proposed, surgical total resection of the mass is generally recognized as the most accepted treatment method. The aim of this study was to evaluate the treatment of eyelid SCC by surgical total resection in a cat. The study material consisted of a short-haired female grey-white stray cat that was brought to Selçuk University, Faculty of Veterinary Medicine, Animal Hospital, Department of Surgery on January 4, 2024 with the complaint of ulcerative tumor in the right eye. After clinical and hematologic examinations, the cat was operated for mass resection. A dose of 0.25 ml bupivacaine was injected subconjuctivally into the bulbar conjunctiva of the T-shaped cartilage, and then the conjunctival tissue from which the third eyelid originated was dissected along all its borders with dissecting scissors and total resection of the tissue was achieved. The final diagnosis of SCC was made after histopathologic examination. Postoperative detailed examination of the eye segments and ocular MR imaging revealed no pathology. In addition, according to the patient's clinical and hematologic findings and radiographic findings of the thorax, no evidence of metastasis was found. During the 1-month postoperative follow-up period, no recurrence or general condition deterioration was detected. In conclusion, we believe that surgical total resection of the third eyelid is a feasible method for the treatment of SCC originating from the third eyelid in cats
Sunflower Crop Yield Prediction Using Machine Learning Methods
Authors: GÖKLER Seda Hatice
Published: December 2024

Sunflower, one of the most important crops, is produced in many countries to meet especially for edible oil demand. Since the sunflower plant is affected by many factors, such as the amount of rain and air temperature, the yield changes from year to year, which has adverse effects on the balance between demand and supply. Because of the product produced in many countries is not enough; it has to be imported. Turkey is one of the world’s leading sunflower importers. The yield must be accurately estimated for the imported quantity to be correct. Importing in large quantities causes inventories, while small quantities cause the sunflower oil demand to not be met. It is used methods such as the direct method, simulation, and remote sensing to estimate sunflower yield. However, these methods have some shortcomings. In this article, machine learning methods, such as Artificial Neural Network, Decision Tree, Support Vector Machine and Random Forest, are used for production prediction. In order to increase the effectiveness of the methods, the values of the hyperparameters are determined by Halving Grid Search method that is tuning method. The methods were implemented in Edirne, which is among the province with the highest sunflower yield in Turkey. The results were evaluated with ANOVA method and performance evaluation metrics, RMSE, RRSE, AE, and R. Decision Tree method, providing the prediction with the lowest error, is determined a suitable method for sunflower yield prediction and then accurate buying decision making.
The Reevaluation of Dostoevsky by the Critic A. Volynsky: “Ecstasies”, Recognition and “Cancellation” of the Author
Authors: Kotelnikov Vladimir
Published: December 2024

The article examines the evolution of Akim Volynsky’s perception and critical assessment of Dostoevsky’s work. The famous literary critic, thinker, art critic Akim Lvovich Volynsky (1863–1926) began studying Dostoevsky’s work in the late 1890s and continued to examine it up to 1923 During this time, the literary canon of Dostoevsky had formed. Volynsky was attracted to the writer’s artistic anthropology, which he discovered in the latter’s novels. In them, the critic found confirmation of his religious and philosophical intuitions. However, in his interpretation of some images, Volynsky deviated from the meanings entrenched in them by the author. His criticism became harsher and more belligerent when Volynsky evaluated the ideas and characters of the novel “Demons.” Volynsky accused Dostoevsky of subjective hostility to the radical “young Russia.” The critic’s last speech about Dostoevsky was given in 1923 In it, the critic reproached the novelist for the latter’s dualistic view of the world and man. At that time, Volynsky himself became a zealous supporter of the monistic worldview. From this viewpoint, he found duality and schematism in the writer’s imagery. His concluded that scholasticism prevails in Dostoevsky’s work, and that it does not contain a full-fledged artistic depiction of life. Such Dostoevsky, according to Volynsky, is outdated, irrelevant for the present, does not belong among literary classics and should remain in the domain of literary legend.
Finerenone: Will It Be a Game-changer?
Authors: Khullar Dinesh , Gupta Anish Kumar , Singh Kulwant
Published: December 2024

Heart failure (HF) is a major contributor to hospitalisations and accounts for 7% of cardiovascular-related deaths, with patients who have chronic kidney disease and type 2 diabetes at heightened risk. Existing treatment guidelines inadequately address these comorbidities. Steroidal mineralocorticoid receptor antagonists (MRAs) are commonly used in HF with reduced ejection fraction but pose risks, such as hyperkalaemia and acute kidney injury. Finerenone, a non-steroidal MRA, offers a safer alternative, with higher selectivity, reduced electrolyte disturbances and beneficial effects on heart and kidney tissues. Preclinical studies show anti-inflammatory and anti-fibrotic effects, while phase III trials (ARTS and ARTS-HF) demonstrated fewer hyperkalaemia incidents compared with spironolactone. In phase III trials (FIDELIO-DKD and FIGARO-DKD), finerenone reduced HF hospitalisations by 22% in patients with chronic kidney disease and type 2 diabetes. The FINEARTS-HF trial found that finerenone significantly reduced the risk of worsening HF events or CV death in patients with HF with mildly reduced or preserved ejection fraction. Its combination with therapies, such as sodium–glucose cotransporter 2 inhibitors, shows promise and ongoing trials, such as REDEFINE-HF, FINALITY-HF and CONFIRMATION-HF, are investigating its efficacy in other HF phenotypes. These studies will further establish the role of finerenone in managing cardio-renal-metabolic diseases.
Cardiovascular Implications of Non-steroidal Anti-inflammatory Drugs: A Comprehensive Review, with Emphasis on Patients with Rheumatoid Arthritis
Authors: Ikdahl Eirik , Kerola Anne , Sollerud Eli , Semb Anne Grete
Published: December 2024

This review examines the cardiovascular risks associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs), both traditional NSAIDs and cyclooxygenase-2 selective inhibitors (COXIBs). It describes the history of traditional NSAIDs and the development of COXIBs to explain why their cardiovascular side effects were unnoticed for many decades. Further, the review presents the mechanism of action of NSAIDs, to elucidate the possible underlying basis for why they are associated with an increased risk of cardiovascular disease. Finally, data on the cardiovascular risk with NSAID use in patients with rheumatoid arthritis are presented, and we propose possible explanations for why the risk of cardiovascular side effects in these patients seems to be less pronounced than in the general population.
Overview of the Burden and Challenges of Hypertension in Asia-Pacific
Authors: Shariff Raja Ezman Raja , Jiang Haowen , Yap Jonathan , Tan Shyn Yi , Cuenza Lucky , Dwiputra Bambang , Habib Faisal , Chang Wei-Ting , Chimura Misato , Ulziisaikhan Ganchimeg , Lee Derek Pok Him , Malis Vorn , Hewarathna Uditha Indika , Choi Kang-Un , Cho Dong-Hyuk , Cader F Aaysha , Gan Gary , Arshad Akmal , Surunchupakorn Purich , Nguyen Quang Ngoc , Jafar Tazeen Hasan , Pronyk Paul , Tiksnadi Badai , Dalakoti Mayank , Sin Kenny , Tan Jack WC
Published: December 2024

There remains great heterogeneity in the availability of data and approaches in managing hypertension in Asia-Pacific. A narrative review was performed to better understand the epidemiology of hypertension and challenges in hypertension care provision regionally. The data obtained were discussed under five domains: epidemiology; hospitalisation and financial impact; medication prescription; national guidelines, societies and measures; and barriers and challenges in managing hypertension. Sixteen countries were included, with the prevalence of hypertension ranging between 10.6% and 48.3%. Rates of undiagnosed, untreated and uncontrolled hypertension were alarming throughout the region, with various factors from the five major domains contributing to this, such as urbanisation, gender and socioeconomic status. Data on care provision were generally sparse. Although various measures and policies exist in individual countries to help combat hypertension, challenges have also been identified: some are systemic, while others appear more granular and culturally influenced. Collaboration between stakeholders between countries is crucial to effectively tackle these issues.
The Evaluation of the Quality and Content of YouTube Videos as a Source of Aerobic Exercise Training for Diabetic Individuals
Authors: Tüfekçi Bengisu , Usgu Günseli , Özcan Esra Nur
Published: December 2024

Purpose: This study aimed to examine the quality and characteristics of aerobic exercise training videos for diabetic individuals published on YouTube.
Methods: In this study, 57 videos were included by searching with the keywords "aerobics, exercise, diabetes". For the reliability assessment, the modified DISCERN scale and Journal of the American Medical Association (JAMA) criteria were used and for the quality and usefulness assessment, the Global Quality Scale (GQS) was used.
Results: In our study, it was observed that most of the videos ( 64.9%, n=37) we analysed (n=57) were produced by non-health video sources. Although DISCERN scores of videos produced by healthcare professionals (3.15±0.81) showed a statistically significant difference compared to videos produced by non-health video producers (2.46±0.93), they were found to be more reliable (p
GENERAL PRINCIPLES OF FORMALIZATION OF TECHNOLOGICAL PROCESS CONTROL OF MINING PRODUCTION IN A DYNAMIC DISTRIBUTED SYSTEM
Authors: Morkun V. S. , Morkun N. V. , Hryshchenko S. M. , Shashkina A. A. , Bobrov E. Y.
Published: December 2024

Context. The problem of synthesis, modeling, and analysis of automated control of complex technological processes of mining production as a dynamic structure with distributed parameters.
Objective. On the example of the technological line of ore beneficiation, the general principles of formalization of control of mining production processes as a dynamic system with distributed parameters are considered.
Method. The modeling of interactions between individual components of the control system is carried out using the methods of coordinated distributed control. In accordance with this approach, the technological line is decomposed into a set of separate subsystems (technological units, enrichment cycles). Under these circumstances, the solution to the global optimization problem is also decomposed into a corresponding set of individual subproblems of optimizing the control of subsystems. To solve the global problem, this formulation uses a two-level structure with coordinating variables that are fed to the input of local control systems for technological units and cycles. At the lower level of control, sets of subtasks have independent solutions, coordinated by the coordinating variables formed at the upper level.
Results. The paper proposes a method for forming control of a distributed system of technological units of an ore dressing line based on the decomposition of the dynamics of the distributed system into time and space components. In the spatial domain, the control synthesis problem is solved as a sequence of approximation problems of a set of spatial components of the dynamics of the controlled system. In the time domain, the solution of the control synthesis problem is based on the methods of synthesizing control systems with concentrated parameters.
Conclusions. The use of the proposed approach to the formation of technological process management at mining enterprises of the Kryvyi Rih iron ore basin will improve the quality of iron ore concentrate supplied to metallurgical processing, increase the productivity of technological units and reduce energy consumption.
Laser additive manufacturing of metal-ceramic materials
Authors:   Khristianovich Institute of Theoretical and Applied Mechanics SB RAS, Malikov A.G. , Golyshev Alexander A. ,   Khristianovich Institute of Theoretical and Applied Mechanics SB RAS
Published: December 2024

The study explores the possibility of manufacturing metal-ceramic materials using two laser manufacturing technologies: Direct Metal Deposition (DMD) and Laser Surface Cladding (LSC). The physical phenomena occurring in these technologies are demonstrated. Similarity laws are applied to describe the geometric characteristics of clad tracks. The structure-phase composition of the resulting coatings is determined using synchrotron radiation. Mechanical properties are measured.
Türkiye’de Bilgi ve Belge Yönetimi Araştırmacılarının İnterdisipliner Yayın Kalıpları: Disiplin Sınırlarını Aşmak
Authors: Yayla Kemal
Published: December 2024

This study examines the interdisciplinary publication patterns of Information and Document Management (IDM) / Information and Records Management researchers in Turkey, determining whether their academic publishing trends align with global tendencies in the field. A data-driven and reproducible research methodology was adopted. Journal articles of 100 IDM researchers from 13 active universities in Turkey were compiled from the YÖK Academic database. Additionally, the publications were analyzed using respective journals obtained from the TR Dizin database. Word2Vec was utilized to identify semantic relationships, UMAP was used for visualization, and the Radius of Gyration (ROG) was computed to express researchers’ interdisciplinary tendencies quantitatively. T-tests and ANOVA were applied to assess differences based on demographic variables. The findings reveal that the average ROG value of IDM researchers in Turkey is 7.23, indicating a general tendency to transcend disciplinary boundaries. No significant differences in interdisciplinary tendencies were found based on academic rank, gender, or institution. The study deepens the understanding of the interdisciplinary nature of the IDM field, introduces methodological innovations through advanced data analysis methods, and contributes to the literature by creating a unique dataset. Future research should explore interdisciplinary tendencies in the IDM field by utilizing more extensive datasets and conducting international comparative analyses.
Bilgi ve Belge Yönetimi Bölümü Öğrencilerinin İş Yeri Örgüt Kültürü Beklentileri
Authors: Alaca Erdinç
Published: December 2024

Örgüt kültürü, örgütü oluşturan unsurların etkileşimiyle oluşmakta, kurumsal performansa yön vermektedir. Personel ise kültürün oluşturulması ve aktarılması süreçlerinde rol oynamaktadır. Kültürün aktarılabilir özelliği uygun örgüt kültürüne sahip olunduğunda olumlu sonuçlar doğurmaktadır. Bu nedenle mevcut örgüt kültürünün yeni çalışanların beklentisiyle uyumu kurum ve çalışan açısından önemlidir. Bu araştırma kapsamında Ankara’daki Bilgi ve Belge Yönetimi (BBY) Bölümlerinde eğitim gören 4. sınıf öğrencilerinin iş yeri örgüt kültürü beklentilerinin saptanması amaçlanmıştır. Katılımcıların nasıl bir örgüt kültürüne dâhil olmak istedikleri, kuruma bakış açılarını olumsuz etkileyecek unsurların ve çalışmak istedikleri kurumların özelliklerinin neler olduğu sorularına yanıt aranmıştır. Araştırmada betimleme yöntemi kullanılmış ve anket tekniğinden yararlanılmıştır. 101 katılımcıya anket uygulanmıştır. Araştırma sonucunda katılımcıların iş hayatında dâhil olmak istedikleri örgüt kültürünün ağırlıklı olarak iş birliği ve yaratıcı kültür karışımı bir kültür olduğu ortaya çıkarılmıştır. Yenilikçi düşüncelerin dikkate alınmaması, iş yükü dağılımında dengesizlik gibi uygulamalar katılımcıların kuruma bakışını yüksek düzeyde olumsuz etkilemektedir. Katılımcıların, yenilik isteği ve vizyonu olan, eğitim ve gelişime açık kurumlarda potansiyellerini daha iyi yansıtma niyetinde oldukları saptanmıştır. Kurumlarda mevcut kültür ile hedeflenen kültür uyumu göz ardı edilmemelidir. Katılımcılarda örgüt kültürüne karşı algı ve farkındalık yaratılmalı, kurumlar ise kültürel beklentileri dikkate almalıdır.
Araştırma Kütüphanelerinde Hizmet Başarısının Tanımlanması: İSAM Kütüphanesi Örneği
Authors: Değer Mehmet Kürşat
Published: December 2024

Bu çalışmada, Nuri Taşkın’ın aynı isimli doktora tezinden türetilen “Araştırma Kütüphanelerinde Hizmet Başarısının Tanımlanması: İSAM Kütüphanesi Örneği” başlıklı kitabının incelenmesi amaçlanmıştır. Kitap, araştırma kütüphanelerinin hizmet başarısını etkileyen faktörlerin, kullanıcı görüşleri doğrultusunda İslâm Araştırmaları Merkezi (İSAM) Kütüphanesi örneklemiyle değerlendirilmesini kapsayan dört bölümden oluşmaktadır. Bu kitapla araştırmacılar, araştırma kütüphaneleri ve İSAM Kütüphanesi hakkında kapsamlı bilgiler elde etmenin yanı sıra hizmet başarısı konusunda nitel bir değerlendirmenin sonuçlarına ulaşabilecektir.
STATE BOREDOM IN ONLINE CLASSROOMS: A STUDY OF NOVICE AND EXPERIENCED IRANIAN EFL TEACHERS
Authors: Estaji Masoomeh , Sadr Seyedeh Azadeh
Published: December 2024

Teachers and students frequently experience positive and negative emotions in EFL classrooms. Boredom is a negative feeling whose detrimental influence on various aspects of the learning process and achievement has been well established. However, in the EFL context, particularly among EFL teachers, this aspect remains under-examined. Using a mixed-methods research design, the current study examined 263 Iranian novice and experienced EFL teachers with online teaching experience to compare their state boredom and perceptions of its signs. For qualitative analysis, 15 novice and 15 experienced teachers were selected from the respondents to review their open-ended questionnaire answers. Additionally, 16 teachers participated in a semi-structured interview. The results of Mann-Whitney U-test revealed a significant difference in state boredom between teacher groups, with novice teachers experiencing higher level of boredom in online classrooms. Qualitative analysis using MAXQDA showed differing perceptions of boredom between novice and experienced teachers in online settings. Novice teachers primarily viewed boredom as attention failure, while experienced teachers had a deeper understanding, including loss of motivation and enthusiasm. The results suggest that targeted support and training for novice teachers in online environments are critical approaches to enhance engagement and reduce boredom, fostering a more comprehensive understanding of motivational factors.
ДОСЛІДЖЕННЯ НИЗЬКОТЕМПЕРАТУРНИХ ПРОЦЕСІВ ОПРІСНЕННЯ ВОДИ
Authors: Мординський Всеволод Петрович , Бурдо Алла Костянтинівна , Фатєєва Яна , Грещук В. П.
Published: December 2024

В роботі проведено аналіз установок блочного виморожування. Проаналізовано основні методи вилучення води з харчових рідин. Обґрунтовано шляхи зменшення витрат енергії та інтенсифікації процесу формування блоку льоду. Запропоновано основні підходи до спрощення цього процесу з енергетичної точки зору та з точки зору витрат часу. Досліджено кінетику утворення крижаної брили. Виявлено основні недоліки процесу заморожування. Запропоновано шляхи удосконалення блокових морозильних установок, які допоможуть вирішити ці проблеми. Показано, що енергетична ефективність збільшується при рециклінгу льоду, використанні його енергії для переохолодження холодильного агенту перед дроселюванням. Інтенсифікація процесу кристалізації проходить за ефектом «термічного парадоксу». Констатовано, що при певних узгоджених конструктивних і робочих параметрах відбувається зниження теплового опору в ланцюжку «холодоагент – поверхня кристалізатора – розчин». Запропонована методика розрахунку установок блочного виморожування для задач опріснення води. В основі алгоритму розрахунку число фазового переходу та дифузійне число Фруда. Систематизовано дані з моделювання процесів низькотемпературного опріснення води. Визначено основні завдання розрахунку, експерименту та оптимізації процесу заморожування блоку. Наведено результати експериментального та аналітичного моделювання процесів опріснення води. Наведено результати досліджень, які дозволяють визначити раціональні режими організації процесів опріснення солоної води в блокових морозильних установках.
РОЗРОБКА ТА ДОСЛІДЖЕННЯ МІКРОХВИЛЬОВОГО ШНЕКОВОГО ЕКСТРАКТОРУ БЕЗПЕРЕРВНОЇ ДІЇ
Authors: Всеволодов Олександр Миколайович , Аль-Хамад Ілля Малекович , Терзієв Сергій Георгійович
Published: December 2024

Проведено критичний аналіз джерел з індустрії харчової промисловості та проблематику розвитку сфери виготовлення фітоекстрактів. Визначено наукові протиріччя традиційного обладнання для екстрагування рослинної сировини. На кафедрі ПОЕМ було сформовано науково-технічну гіпотезу для процесу екстрагування з використанням мікрохвильового випромінювання. Використання мікрохвильової енергії для екстрагування біологічно-активних речовин дозволить значно підвищити ефективність процесу за рахунок інтенсивного впливу МХ на матеріал та руйнування клітинних структур (за рахунок бародифузії), що збільшить вихід цільових фітохімічних речовин, знизить енерговитрати та скоротить час екстрагування порівняно з традиційними методами. Спираючись на параметричну модель процесу екстрагування у мікрохвильовому полі методами теорії подібності, було отримано структуру критеріальної моделі  для шару сировини. Основним матеріалом для проведення серії експериментів, була рослинна сировина соя. Експериментальний стенд включав резонаторну камеру, шнековий транспортер, джерела електромагнітної енергії, завантажувальний і розвантажувальний бункери, система подачі екстрагенту, елементи керування установкою. Дуже важливими результатами дослідження є залежності кінцевої концентрації  екстракту від потужності магнетрону та від гідромодуля. Аналіз даних експериментальних досліджень показав перевагу мікрохвильового екстрагування, порівняно із традиційними методами екстрагування. Підвищення потужності МХ-енергії може суттєво підвищити кінцеву концентрацію і істотно знизити тривалість, тим самим, знизити витрати енергії на процес екстрагування. Гідромодуль і потужність мікрохвильового поля є найбільш важливими параметрами при виборі раціонального режиму роботи екстракційного обладнання. Узгодження цих параметрів дозволяє збільшити значення коефіцієнта масовіддачі при екстрагуванні.
A Study of Challenges and Opportunities in Enhancing Smart Grids with Cloud Computing
Authors:   Senior Systems Engineer, SIEMENS Technologies and Services, Bengaluru, Karnataka, India, Srinivas Chippagiri , Narayan Mahesh ,   Software Architect, SIEMENS Technologies and Services, Bengaluru, Karnataka, India
Published: December 2024

The integration of cloud computing into smart grids represents a transformative step toward enhancing
their efficiency, scalability, and sustainability. This paper explores the intricacies and strategic opportunities of this
integration, addressing technical and infrastructure challenges alongside technologies that enable seamless synergy. It
also examines the regulatory and policy implications associated with this convergence. The study provides a
comprehensive analysis supported by data tables and code snippets, offering practical insights into the real-world
application of smart grid-cloud integration. This work serves as a valuable resource for researchers and industry
professionals aiming to capitalize on this innovation.
Ustawodawstwo sejmowe doby bezkrólewia 1733 r. a bezpieczeństwo wewnętrzne i zewnętrzne Rzeczypospolitej
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Tomaszewski Michał
Published: December 2024

This article deals with matters concerning sejm legislation during the 1733 interregnum. As a contributory text, it attempts to answer the question to what extent the two undisturbed sejms raised the extremely important matter of state defence. The conclusions of the Convocation and Electoral Sejm of 1733 are analysed, i.e. the general confederation concluded at the Convocation and the constitutions of the Electoral Sejm, which have not yet been analysed. The text also examines the limited enlargement of the Lithuanian army at the end of 1733.
Powiat wielicki w okresie I wojny światowej w świetle pamiętnika Mariana Dydyńskiego z Raciborska
Authors:   Uniwersytet Jagielloński w Krakowie, Paluch Piotr
Published: December 2024

The aim of this article is to present Marian Dydyński’s from Raciborsko diary account in the context of World War I. The main emphasis in my work will be on the economic aspect: inflation, destruction, robberies, the terrible condition of the farm, the provision of the Austrian army, and after its withdrawal – the Russian army, both of which were often obtained by force. I will present these events from the perspective of a landowner who, unlike other people around him, did not decide to leave his land and persistently guarded his possessions.
Niemiecka propaganda gospodarcza wobec Polaków w Generalnym Gubernatorstwie 1939–1945
Authors:   Uniwersytet Ignatianum w Krakowie, Kot Przemysław
Published: December 2024

Propaganda is an inherent element of wartime activities and has been used since the inception of statehood and the conduct of wars by mankind. This article will focus on German propaganda in the General Government directed at the Polish society throughout the war. Thematically, only issues related to economic propaganda will be analyzed. The first part of this article will provide a brief overview of theories on propaganda. The second part will characterize the propaganda system established by the German occupiers in the General Government. In the third and main part, German propaganda aimed at Poles related to economic topics will be characterized. The primary sources for this work will be two newspapers, „Nowy Kurier Warszawski” and „Goniec Krakowski”, which were published throughout the governorate. Content analysis and critical source analysis methods will be utilized.
Wpływ reform wojskowych na kształtowanie ustroju demokratycznego w Hiszpanii (1975– 1996)
Authors:   Uniwersytet Gdański, Hodlevska Valentyna
Published: December 2024

This article discusses the key military reforms in Spain from 1975 to 1996 and their significance in the country’s transition from Franco’s dictatorship to a democratic regime. Following General Franco’s death in 1975, Spain faced the challenge of transforming its authoritarian political system into a stable democracy. One of the most critical elements of this process was the reform of the military structures, which played a pivotal role in maintaining the old regime. The article analyzes significant changes in the Spanish armed forces, including the adoption of a new military criminal code, reforms related to compulsory military service, and steps towards the professionalization of the army. It also examines the impact of these reforms on civil-military relations, particularly in reducing hostile sentiments towards the military and increasing its popularity and acceptance among citizens. The article highlights the role of King Juan Carlos as a key mediator during the transition period, who managed to persuade the military to accept democratic changes. Military reforms contributed to limiting the military’s ability to intervene in internal politics, which was crucial for consolidating the new democratic regime. These reforms led to the Spanish army ceasing to act as a political arbiter and focusing on its primary defense tasks, which significantly impacted the stabilization and development of democratic Spain.
Camellia sinensis L. (Green Tea): Bioactive Compounds and Pharmacological Properties – A Comprehensive Review
Authors: MARINA Alexia-Desirée , FILIP Lorena A. , MARC Romina A.
Published: December 2024

Medicinal plants have become increasingly preferred over drugs due to the sense of well-being they promote, thanks to their rich content in bioactive compounds with many health benefits, as well as their lack of adverse effects compared to pharmaceuticals. At the same time, they can relieve the symptoms of some conditions and also contribute to the prevention of various chronic diseases, including obesity, diabetes, and cancer. Camellia sinensis L., known as the plant from which green, black, and oolong teas are obtained, as well as other varieties, is one of the most famous medicinal plants, bringing a multitude of benefits to the human body, mainly through the compounds in its leaves, the largest proportion being represented by catechins, a type of polyphenol recognized for their strong antioxidant properties. EGCG (epigallocatechin gallate), the most important and abundant catechin, is known for its ability to neutralize free radicals and reduce oxidative stress.Although less studied, the flowers of this plant are also rich in bioactive compounds found in the leaves, along with unique compounds but also others with multiple therapeutic properties. Research indicates that the regular consumption of green tea (Camellia sinensis L.) significantly enhances life quality and promotes longevity by lowering the risk of cardiovascular diseases and certain types of cancer, including colorectal and gastric cancers.
Grape Pomace Valorisation: Nutritional Properties and Sustainable Applications in Agriculture and Food Technology
Authors: ZMUNCILĂ Alexandru , PĂUCEAN Adriana , MAN Simona Maria , CHIŞ Simon-Maria
Published: December 2024

The wine industry generates a significant amount of waste, producing over 14 million tons of by-products from wineries in Europe alone. The resulting waste has an acidic composition and high levels of polyphenols. Thus, it is resistant to decomposition, making it an environmental threat. Grape pomace contains important nutrients for valorisation, which are dietary fiber, proteins, lipids, and polyphenols. This review summarizes the nutritional composition of grape pomace and discusses various strategies for its sustainable utilization, including animal feed, composting, advanced extraction techniques of phenolic compounds, fermentation, and food fortification. The current review aims to underline the importance of grape pomace valorisation in terms of environmental sustainability and human health, thereby justifying further research and implementation in this field.
Molecular Analysis of the Species Dracocephalum moldavica L.
Authors: SIMEA Ștefania-Alexandra , FLORIAN Teodora , BUTIUC-KEUL Anca , DUDA Marcel
Published: December 2024

There is a growing global trend in the consumption of cultivated medicinal and aromatic plants and an increasing demand for medicinal plants for the production of herbal medicines, health products, dietary supplements, and cosmetic products. The raw plant material from medicinal plant crops is insufficient to meet the needs of this industry. There is a preference for cultivated plant material because most pharmaceutical companies prefer raw materials that meet the required quality standards. Therefore, expanding the cultivation of medicinal plant and introducing new species into cultivation is becoming an important objective. These efforts are complemented by other advantages of cultivation (e.g., modern mechanized agricultural techniques, irrigation, fertilization, and mechanized harvesting). Molecular characterization of the species Dracocephalum moldavica, was focused on analysing the genetic structure of a cultivated plant population. Genetic analysis can provide important data regarding intra- and interpopulation genetic polymorphism, closely correlated with the adaptive capacity of the species to different pedo-climatic conditions, as well as the biosynthetic capacity of pharmacologically active compounds. This enables the accurate identification and selection of new valuable genotypes. Molecular analysis can be performed using DNA molecular markers, among which SSR (simple sequence repeats) and ISSR (inter simple sequence repeats) markers are frequently used due to their high reproducibility, relatively low cost, and avoidance of radioactivity (as is the case with other molecular markers). In this study, ISSR markers revealed genetic polymorphism of cultivated plants.
Autotransplantation of the kidney in locally advanced gastrointestinal stromal tumor of the duodenum
Authors: Rasulov R. I. , Muratov A. A. , Ponomarenko D. M.
Published: December 2024

Surgical intervention remains a fundamental component of radical treatment for locally advanced gastrointestinal stromal tumors of the duodenum. The paper presents a clinical experience in the diagnosis and organ-sparing surgical treatment of a gastrointestinal stromal tumor located in the lower horizontal segment of the duodenum, which involved the left kidney. The tumor was excised en bloc along with the anatomically involved structures, and then the left kidney was isolated from the excised tissue and successfully autotransplanted to a heterotopic position. The authors argue that ex vivo isolation of the kidney from the tumor mass, followed by heterotopic autotransplantation, represents a promising organ-sparing technique in oncological surgery for locally advanced abdominal tumors. Notably, the biological characteristics of the tumor are to be considered when planning organ-sparing surgical procedures.
Characteristics of intestinal microbiota in the pathogenesis and clinical course of acute pancreatitis
Authors: Sitsskiy A. A. , Kakotkin V. V. , Agapov M. A.
Published: December 2024

Aim. To analyze the most promising scientific and practical directions regarding the role of intestinal microbiota and its metabolites in the pathogenesis and clinical course of acute pancreatitis.

Materials and methods. The study involved a systematic literature review of the databases PubMed, EMBASE, and Cochrane for the last 20 years. A total of 5 meta-analyses, 234 clinical trials, 127 reviews, and 428 experimental studies were identified. Ultimately, 36 clinical trials, 2 reviews, and 18 experimental studies were selected for the inclusion. The systematic review was carried out in accordance with PRISMA recommendations.

Results. The structure of the intestinal microbiota significantly differs in healthy control groups and patients with acute pancreatitis. The microbiota of patients with acute pancreatitis closely correlates with systemic inflammation and intestinal barrier dysfunction. Cases of severe acute pancreatitis revealed an increase in Enterococcus, Proteobacteria, Escherichia, and Shigella, alongside a decrease in overall microbiome diversity and in Bifidobacterium, Prevotella, Faecalibacterium, Blautia, Lachnospiraceae, and Ruminococcaceae. Short-chain fatty acids, the concentration of which in the blood may indicate an increase in intestinal wall permeability, are directly involved in the pathogenesis of acute lung injury associated with acute pancreatitis.

Conclusion. Further study into the composition of the intestinal microbiota, its metabolites, and potential modulation strategies in various patient groups obtains high potential as a foundation for new diagnostic, therapeutic, and preventive approaches to acute pancreatitis.
Risk factors for the development of pancreatic fistula after pancreaticoduodenectomy
Authors: Ataeva A. N. , Mamedov A. F. , Kurskov A. O. , Kozodaeva M. V. , Dalgatov K. D , Sazhin A. V.
Published: December 2024

Pancreatic fistula refers to the most common and serious complication following pancreaticoduodenectomy. Various prognostic scoring systems have been developed and validated to reduce the risk of postoperative pancreatic fistula. These prognostic scores are based on preoperative data and intraoperative assessments of gland density, pancreatic duct diameter, and other parameters. The most frequently used and widely recognized prognostic scores include FRS, a-FRS, and ua-FRS. Evolution in instrumental methods of diagnosis, development of artificial intelligence, and accumulation of experience in managing patients with periampullary malignancies shift the focus towards preoperative evaluation based on CT data.
Endovascular surgery in the treatment of portal hypertension complications
Authors: Zatevakhin I. I. , Shipovskiy V. N. , Tsitsiashvili M. Sh. , Monakhov D. V.
Published: December 2024

Aim. To describe the main endovascular interventions used in portal hypertension. The paper presents modern endovascular procedures for treating patients with portal hypertension and varicose transformation of the esophageal and gastric veins: transjugular intrahepatic portosystemic shunt, balloon-occluded retrograde transvenous obliteration, balloon-occluded antegrade transvenous obliteration, partial embolization of the splenic arteries and gastric veins. The study extensively discusses the radical shunting surgery related to portal hypertension – transjugular intrahepatic portosystemic shunt. The paper involves historical aspects of the development of this treatment procedure, indications, techniques, variations depending on the nature of the disease and clinical situation, along with an analysis of the surgical approach in the event of endovascular intervention complications.
A literatura infantil para prevenção da violência sexual: análise de matériais
Authors: Bortolozzi Ana Cláudia , Sayuri Tanaka Brenda
Published: December 2024

A violência sexual contra crianças é um fenômeno alarmante, com graves implicações para o desenvolvimento das pessoas vitimizadas e que, por isso, deve ser alvo de políticas públicas de prevenção na área da saúde e da educação e um bom recurso pedagógico para isso é o uso de livros. Este estudo qualitativo, tipo documental, teve por objetivo analisar a literatura infantil sobre prevenção à violência sexual contra crianças. Foram analisados 12 livros localizados no site comercial amazon.com, resultando três categorias temáticas: (1) Conteúdo sobre violência sexual: a pessoa autora da violência geralmente é homem, está perto da criança, pede segredo e ela deve se defender e denuciar; (2) Vertentes de educação em sexualidade: Biológica - nomeação de partes íntimas do corpo e noção de privacidade, Religiosa - proteção de um corpo que é criação de Deus, e de Direitos Humanos - proteção da criança enquanto função da família e do Estado; e (3) Representação da diversidade: ênfase em corpos brancos, poucas imagens de pessoas negras e amarelas e nenhum indígena, prevalência de uma classe socioeconômica média e predomínio de corpos sem deficiência, magros e altos. A maior parte dos livros usa personagens humanos (poucos são animais ou figuras abstratas); alguns utilizam rimas para facilitar a linguagem e quase todos apresentam recomendações aos/às adultos/as que devem acompanhar a leitura. Alguns livros são mais completos em conteúdo, enquanto outros são mais superficiais; alguns são tendenciosos a valores mais conservadores ou a padrões familiares normativos e heterossexuais. Entretanto, a mensagem de identificação da violência e meios de proteção são explícitos em todos eles. Apesar de algumas ressalvas, conclui-se que há bons materiais que podem ser utilizados e adaptados para processos de educação em sexualidade na infância.
Crise no transtorno bipolar x terapia cognitivo comportamental: identificação e tratamento
Authors: Domingues Afonso Beatriz , Modenesi Pucci Silvia Helena
Published: December 2024

O Transtorno Afetivo Bipolar (TB) pode impactar significativamente a vida social, profissional e familiar dos indivíduos afetados. A instabilidade de humor e a ocorrência de episódios de crises podem gerar dificuldades no ambiente de trabalho, nos relacionamentos interpessoais e na rotina diária, o que reforça a importância de,identificar e abordar precocemente esses fatores de risco. Objetivo: Identificar os principais fatores de risco para crises no TB, bem como as principais técnicas da Terapia Cognitivo Comportamental (TCC) para o controle dessas crises. Metodologia: Revisão integrativa da literatura, utilizando descritores catalogados do Desc/Mesh, bem como bases científicas indexadas. Resultados: Como risco para crises no TB, foram identificados abuso sexual na infância, falta de suporte familiar, disfunção cognitiva causada pelo transtorno, ausência de psicoeducação, dificuldade de adaptação a medicamentos, uso abusivo de substâncias químicas, distúrbios do sono e do ciclo circadiano. Em relação a Terapia Cognitivo Comportamental, identificou-se técnicas de psicoeducação para pacientes e familiares, resolução de problemas, autogestão e reflexão sobre problemas,normalização do sono, fortalecimento das habilidades de resolução de problemas, autonomia do paciente no manejo dacondição, intervenções nutricionaise promoção do bem-estar. Conclusão: as estratégias terapêuticas buscam não apenas mitigar os sintomas do transtorno, mas também promover o bem-estar e a estabilidade emocional dos indivíduos impactados pelo TB e, o controle dos fatores associados ao aumento do risco das crises, podem auxiliar no tratamento e melhor gestão das crises.
Feasibility of a synchronous, online, group psychological intervention in nonclinical settings
Authors: Arrigoni Flavia , Navarro Guzmán José I.
Published: December 2024

Introduction: it was considered appropriate to design psychological interventions in non-clinical contexts (community, academic-clinical and academic-non-clinical), in order to obtain data on the feasibility, acceptance and satisfaction with the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (PU) in group, online, synchronous format. Objective: to explore the feasibility, acceptance and satisfaction of participants regarding a psychological intervention based on the application of the synchronous online group PU in various non-clinical contexts. Method: study with a quantitative, exploratory-descriptive, and interactive approach, with a quasi-experimental, pre-post test design for paired samples. The incidental sample of each of the three studies carried out consisted of a total of 9 women with a diagnosis of breast cancer (current or in remission), 9 UCA students who requested psychological care from the SAP at the beginning of the 2020-2021 academic year, and 13 students from the Aula Universitaria de Mayores of the UCA. Instruments: to assess feasibility we used the Satisfaction / Opinion Scale on Treatment (Spanish adaptation by Borkovec & Nau), an ad hoc Personal Assessment Survey on various aspects of the psychological intervention (Schedule, Themes, Modality of the sessions, Shared material and Therapist) which included an open question “Suggestions, comments or opinion”. Results: the preliminary results obtained are encouraging and show the feasibility of the PU in the format and contexts applied.
Violencia psicológica en parejas de jóvenes universitarios. Estudio comparativo en función de la variable edad
Authors: Baile Torres Patricia Beatriz
Published: December 2024

El objetivo del presente estudio fue analizar la prevalencia de las manifestaciones de maltrato psicológico y de los estilos de amor en jóvenes universitarios, determinando las diferencias y relaciones existentes en función de la edad. Se administró un cuestionario de datos sociodemográficos elaborado ad hoc, la “Escala Triangular del Amor” (Triangle Love Scale, TLS) y “Cuestionario de Maltrato Psicológico en la Pareja” (CMPar) a una muestra probabilística constituida por 1290 sujetos, de edades comprendidas entre los 17 y 25 años. Para realizar el análisis comparativo se dividió la muestra en cuatro grupos por intervalos de edad (17-19;20-21;22-23;24-25). Los resultados mostraron que los más jóvenes (17-19 años) presentaban puntuaciones más elevadas en Pasión e Intimidad, mientras, el grupo de mayor (24-25 años) edad lo hace en la mayoría de las manifestaciones de maltrato psicológico. Asimismo, se encontraron correlaciones significativas (p<0.001) entre los componentes de la TLS y CMPar por intervalos de edad. Consecuentemente, se concluye que el estilo de amor romántico se relaciona positivamente con una mayor tolerancia a manifestaciones de maltrato psicológico, reproduciendo relaciones desiguales y favoreciendo el dominio y la dependencia emocional.