bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods, Figures 1-6, Tables 1-4 from Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry
Authors: Eberlin Livia S. , Norton Isaiah , Dill Allison L. , Golby Alexandra J. , Ligon Keith L. , Santagata Sandro , Cooks R. Graham , Agar Nathalie Y.R.
Published: April 2023

PDf file - 728K
Supplementary Methods, Figure Legend from Dual Role of the Antioxidant Enzyme Peroxiredoxin 6 in Skin Carcinogenesis
Authors: Rolfs Frank , Huber Marcel , Gruber Florian , Böhm Friederike , Pfister Herbert J. , Bochkov Valery N. , Tschachler Erwin , Dummer Reinhard , Hohl Daniel , Schäfer Matthias , Werner Sabine
Published: April 2023

PDF file - 102K
Supplementary Figures 1 - 4 from Dual Role of the Antioxidant Enzyme Peroxiredoxin 6 in Skin Carcinogenesis
Authors: Rolfs Frank , Huber Marcel , Gruber Florian , Böhm Friederike , Pfister Herbert J. , Bochkov Valery N. , Tschachler Erwin , Dummer Reinhard , Hohl Daniel , Schäfer Matthias , Werner Sabine
Published: April 2023

PDF file - 626K, Supplemental Fig. S1: Effect of Prdx6 loss-of-function or overexpression on development, growth, and localization of HPV8-induced papillomas Supplemental Fig. S2: Prdx6 overexpression does not affect induction of DNA double strand breaks, keratinocyte proliferation, mast cells or T cells during DMBA/TPA-induced skin carcinogenesis Suppl. Fig.S3: Prdx6 overexpression does not affect keratinocyte proliferation, inflammation or hemorrhage during HPV8-induced skin carcinogenesis Supplemental Fig. S4: Kinetics of lipid peroxidation in wild-type mice after TPA treatment
Supplementary Figure 2 from Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Authors: Hu Bin , Nandhu Mohan S. , Sim Hosung , Agudelo-Garcia Paula A. , Saldivar Joshua C. , Dolan Claire E. , Mora Maria E. , Nuovo Gerard J. , Cole Susan E. , Viapiano Mariano S.
Published: April 2023

PDF file - 195K, Specificity and efficacy of siRNAs against fibulin-3 and Notch-1
Supplementary Figure 4 from Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
Authors: Teng Michele W. L. , Vesely Matthew D. , Duret Helene , McLaughlin Nicole , Towne Jennifer E. , Schreiber Robert D. , Smyth Mark J.
Published: April 2023

PDF file - 171K, Clodrolip-sensitive macrophages are critical in equilibrium
Supplementary Figure 3 from Strain-Specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer
Authors: Kreisel Daniel , Gelman Andrew E. , Higashikubo Ryuji , Lin Xue , Vikis Haris G. , White J. Michael , Toth Kelsey A. , Deshpande Charuhas , Carreno Beatriz M. , You Ming , Taffner Samantha M. , Yokoyama Wayne M. , Bui Jack D. , Schreiber Robert D. , Krupnick Alexander S.
Published: April 2023

PDF file - 21K, Strain-specific differences in Yac-1 cytotoxcity
Supplementary Figure 2 from Strain-Specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer
Authors: Kreisel Daniel , Gelman Andrew E. , Higashikubo Ryuji , Lin Xue , Vikis Haris G. , White J. Michael , Toth Kelsey A. , Deshpande Charuhas , Carreno Beatriz M. , You Ming , Taffner Samantha M. , Yokoyama Wayne M. , Bui Jack D. , Schreiber Robert D. , Krupnick Alexander S.
Published: April 2023

PDF file - 25K, Cytotoxicity of neutrophils and monocytes/macrophages
Supplementary Table 3 from BMP4 Administration Induces Differentiation of CD133+ Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma
Authors: Zhang Lixing , Sun Hefen , Zhao Fangyu , Lu Ping , Ge Chao , Li Hong , Hou Helei , Yan Mingxia , Chen Taoyang , Jiang Guoping , Xie Haiyang , Cui Ying , Huang Xiaowu , Fan Jia , Yao Ming , Li Jinjun
Published: April 2023

PDF file - 7K, Sequences of siRNA fragments used in this study
Supplementary Figure 1 from Strain-Specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer
Authors: Kreisel Daniel , Gelman Andrew E. , Higashikubo Ryuji , Lin Xue , Vikis Haris G. , White J. Michael , Toth Kelsey A. , Deshpande Charuhas , Carreno Beatriz M. , You Ming , Taffner Samantha M. , Yokoyama Wayne M. , Bui Jack D. , Schreiber Robert D. , Krupnick Alexander S.
Published: April 2023

PDF file - 36K, T cell depletion in AJ mice
Supplementary Figures 1-6, Table 1, Methods from Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
Authors: Murai Junko , Huang Shar-yin N. , Das Benu Brata , Renaud Amelie , Zhang Yiping , Doroshow James H. , Ji Jiuping , Takeda Shunichi , Pommier Yves
Published: April 2023

PDF file - 465K, Figure S1. Chemical structures. Figure S2. Alignment of human PARP1 (hPARP1) and chicken PARP1 (gPARP1) amino acid sequences. Figure S3. Olaparib induces PARP1- and PARP2-DNA complexes in OVCAR4 and SF295 cells. Figure S4. Differential trapping of PARP1 and PARP2 by the different PARP inhibitors in human glioblastoma SF295 cells. Figure S5. PARP1- and PARP2-poisoning by 4-amino-1,8-naphthalimide (4-AN). Figure S6. Monoubiquitination of FANCD2 in response to olaparib. Table S1. DT40 isogenic mutant cell lines used in this study. Plus, Supplementary Materials and Methods
Supplementary Tables 1-3, Figures 1-3 from Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival
Authors: Silva Ines A. , Bai Shoumei , McLean Karen , Yang Kun , Griffith Kent , Thomas Dafydd , Ginestier Christophe , Johnston Carolyn , Kueck Angela , Reynolds R. Kevin , Wicha Max S. , Buckanovich Ronald J.
Published: April 2023

Supplementary Tables 1-3, Figures 1-3 from Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival
Supplementary Methods and Materials from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis
Authors: Kazerounian Shiva , Gerald Damien , Huang Minzhou , Chin Y. Rebecca , Udayakumar Durga , Zheng Ningning , O'Donnell Rebekah K. , Perruzzi Carole , Mangiante Lee , Pourat Jacob , Phung Thuy L. , Bravo-Nuevo Arturo , Shechter Sharon , McNamara Stephanie , DuHadaway James B. , Kocher Olivier N. , Brown Lawrence F. , Toker Alex , Prendergast George C. , Benjamin Laura E.
Published: April 2023

PDF file - 22K
Supplementary Figure 6 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis
Authors: Kazerounian Shiva , Gerald Damien , Huang Minzhou , Chin Y. Rebecca , Udayakumar Durga , Zheng Ningning , O'Donnell Rebekah K. , Perruzzi Carole , Mangiante Lee , Pourat Jacob , Phung Thuy L. , Bravo-Nuevo Arturo , Shechter Sharon , McNamara Stephanie , DuHadaway James B. , Kocher Olivier N. , Brown Lawrence F. , Toker Alex , Prendergast George C. , Benjamin Laura E.
Published: April 2023

PDF file - 26K, Level of EGFR on the surface of human MDA-MB-231 cells
Supplementary Figure 6 from Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2–mTOR Pathway
Authors: Chen Wei , Ma Tao , Shen Xu-ning , Xia Xue-feng , Xu Guo-dong , Bai Xue-li , Liang Ting-bo
Published: April 2023

PDF file - 1.1MB
Supplementary Figure 5 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis
Authors: Kazerounian Shiva , Gerald Damien , Huang Minzhou , Chin Y. Rebecca , Udayakumar Durga , Zheng Ningning , O'Donnell Rebekah K. , Perruzzi Carole , Mangiante Lee , Pourat Jacob , Phung Thuy L. , Bravo-Nuevo Arturo , Shechter Sharon , McNamara Stephanie , DuHadaway James B. , Kocher Olivier N. , Brown Lawrence F. , Toker Alex , Prendergast George C. , Benjamin Laura E.
Published: April 2023

PDF file - 52K, Level of silencing of Akt in RhoB-/- and RhoB+/+ mouse cells
Supplementary Figure 5 from Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2–mTOR Pathway
Authors: Chen Wei , Ma Tao , Shen Xu-ning , Xia Xue-feng , Xu Guo-dong , Bai Xue-li , Liang Ting-bo
Published: April 2023

PDF file - 1.4MB
Supplementary Figure 4 from Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2–mTOR Pathway
Authors: Chen Wei , Ma Tao , Shen Xu-ning , Xia Xue-feng , Xu Guo-dong , Bai Xue-li , Liang Ting-bo
Published: April 2023

PDF file - 1.4MB
Supplementary Figure 3 from Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2–mTOR Pathway
Authors: Chen Wei , Ma Tao , Shen Xu-ning , Xia Xue-feng , Xu Guo-dong , Bai Xue-li , Liang Ting-bo
Published: April 2023

PDF file - 633K
Supplementary Figure 2 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis
Authors: Kazerounian Shiva , Gerald Damien , Huang Minzhou , Chin Y. Rebecca , Udayakumar Durga , Zheng Ningning , O'Donnell Rebekah K. , Perruzzi Carole , Mangiante Lee , Pourat Jacob , Phung Thuy L. , Bravo-Nuevo Arturo , Shechter Sharon , McNamara Stephanie , DuHadaway James B. , Kocher Olivier N. , Brown Lawrence F. , Toker Alex , Prendergast George C. , Benjamin Laura E.
Published: April 2023

PDF file - 21K, RhoB is downregulated in MDA-MB-231 cells using lentivirus shRNA
Supplementary Figure 1 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis
Authors: Kazerounian Shiva , Gerald Damien , Huang Minzhou , Chin Y. Rebecca , Udayakumar Durga , Zheng Ningning , O'Donnell Rebekah K. , Perruzzi Carole , Mangiante Lee , Pourat Jacob , Phung Thuy L. , Bravo-Nuevo Arturo , Shechter Sharon , McNamara Stephanie , DuHadaway James B. , Kocher Olivier N. , Brown Lawrence F. , Toker Alex , Prendergast George C. , Benjamin Laura E.
Published: April 2023

PDF file - 219K, Effects of RhoB deletion on MT-myc induced mammary tumorigenesis in virgin female mice
Supplementary Table 1 from Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels
Authors: Kretzner Leo , Scuto Anna , Dino Pamela M. , Kowolik Claudia M. , Wu Jun , Ventura Patrick , Jove Richard , Forman Stephen J. , Yen Yun , Kirschbaum Mark H.
Published: April 2023

Supplementary Table 1 from Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels
Supplementary Figure Legends 1-2 from Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy
Authors: Emeagi Perpetua U. , Van Lint Sandra , Goyvaerts Cleo , Maenhout Sarah , Cauwels Anje , McNeish Iain A. , Bos Tomas , Heirman Carlo , Thielemans Kris , Aerts Joeri L. , Breckpot Karine
Published: April 2023

PDF file - 60K
Supplementary Figure 2 from Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy
Authors: Emeagi Perpetua U. , Van Lint Sandra , Goyvaerts Cleo , Maenhout Sarah , Cauwels Anje , McNeish Iain A. , Bos Tomas , Heirman Carlo , Thielemans Kris , Aerts Joeri L. , Breckpot Karine
Published: April 2023

PDF file - 117K, Uptake of LV-tSMAC transduced dying human melanoma cells enables dendritic cells to activate tumor-infiltrating lymphocytes.
Supplementary Figure 4 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 680K, Deletion of TREM-1 inhibits cytokine and chemokine production by bone marrow-derived macrophages stimulated with the product of necrotic hepatocytes (PNH)
Supplementary Figure 7 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 306K, Over-expression of the human progesterone receptor (hPR) with a lentivirus in the tumor stroma.
Supplementary Figure 1 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 2.9MB, Targeting strategy for the Trem1 genomic locus and generation of Trem1-deficient mice
Supplementary Figure 4 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 364K, Stromal or epithelial specific deletion of PR-A and PR-B.
Supplementary Figure 1 from Mammary Gland Selective Excision of c-Jun Identifies Its Role in mRNA Splicing
Authors: Katiyar Sanjay , Jiao Xuanmao , Addya Sankar , Ertel Adam , Covarrubias Yolanda , Rose Vanessa , Casimiro Mathew C. , Zhou Jie , Lisanti Michael P. , Nasim Talat , Fortina Paolo , Pestell Richard G.
Published: April 2023

PDF file - 183K
Supplementary Table 7 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Authors: Cheng Alfred S.L. , Lau Suki S. , Chen Yangchao , Kondo Yutaka , Li May S. , Feng Hai , Ching Arthur K. , Cheung Kin F. , Wong Hoi K. , Tong Joanna H. , Jin Hongchuan , Choy Kwong W. , Yu Jun , To Ka F. , Wong Nathalie , Huang Tim H.-M. , Sung Joseph J.Y.
Published: April 2023

Supplementary Table 7 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Supplementary Figures 1-7, Tables 1-6 from miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma
Authors: Jones Kevin B. , Salah Zaidoun , Del Mare Sara , Galasso Marco , Gaudio Eugenio , Nuovo Gerard J. , Lovat Francesca , LeBlanc Kimberly , Palatini Jeff , Randall R. Lor , Volinia Stefano , Stein Gary S. , Croce Carlo M. , Lian Jane B. , Aqeilan Rami I.
Published: April 2023

PDF file - 2MB
Supplementary Table 1 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Authors: Cheng Alfred S.L. , Lau Suki S. , Chen Yangchao , Kondo Yutaka , Li May S. , Feng Hai , Ching Arthur K. , Cheung Kin F. , Wong Hoi K. , Tong Joanna H. , Jin Hongchuan , Choy Kwong W. , Yu Jun , To Ka F. , Wong Nathalie , Huang Tim H.-M. , Sung Joseph J.Y.
Published: April 2023

Supplementary Table 1 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Supplementary Figures 1-5 from Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk
Authors: Brennan Kevin , Garcia-Closas Montserrat , Orr Nick , Fletcher Olivia , Jones Michael , Ashworth Alan , Swerdlow Anthony , Thorne Heather , Riboli Elio , Vineis Paolo , Dorronsoro Miren , Clavel-Chapelon Francoise , Panico Salvatore , Onland-Moret N. Charlotte , Trichopoulos Dimitrios , Kaaks Rudolf , Khaw Kay-Tee , Brown Robert , Flanagan James M.
Published: April 2023

PDF file - 207K
Supplementary Table 3 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 69K, Summary of IHC staining for HBx, Shh, Ihh, Gli2 and PTCH1 among HBV infected patients with HCC
Supplementary Figure 4 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 2.3MB
Supplementary Figure 1 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 4.3MB
Supplementary Material and Methods and Figure Legends from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: April 2023

PDF file, 247K, The file includes robustness analysis, a small-scale example of MPA application, MPA's validation and supplementary methods.
Supplementary Figure 3 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: April 2023

PDF file, 281K, Prediction of lipid content by MPA. (a) The percentage of lipids that were significantly positively correlated (p-value<0.05) to the MPA lipid-scores (blue) or to the gene expression of ACC (gray). (b) The empirical p-values, denoting the significance of the obtained results, in a minus log10 scale. Similar results were obtained when considering the gene expression levels of FAS and ACL (Supplementary Table 3).
Supplementary Table 1 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 68K
Supplementary Tables 1-4 from Dissection of T-cell Antigen Specificity in Human Melanoma
Authors: Andersen Rikke Sick , Thrue Charlotte Albæk , Junker Niels , Lyngaa Rikke , Donia Marco , Ellebæk Eva , Svane Inge Marie , Schumacher Ton N. , thor Straten Per , Hadrup Sine Reker
Published: April 2023

PDF file - 75K
Supplementary Table 5 from Dissection of T-cell Antigen Specificity in Human Melanoma
Authors: Andersen Rikke Sick , Thrue Charlotte Albæk , Junker Niels , Lyngaa Rikke , Donia Marco , Ellebæk Eva , Svane Inge Marie , Schumacher Ton N. , thor Straten Per , Hadrup Sine Reker
Published: April 2023

XLS file - 41K
Supplementary Figure 5 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 5.6MB
Supplementary Figure 4 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 361K
Supplementary Figures 1-3 from Dissection of T-cell Antigen Specificity in Human Melanoma
Authors: Andersen Rikke Sick , Thrue Charlotte Albæk , Junker Niels , Lyngaa Rikke , Donia Marco , Ellebæk Eva , Svane Inge Marie , Schumacher Ton N. , thor Straten Per , Hadrup Sine Reker
Published: April 2023

PDF file - 170K
Supplementary Figure 2 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 3.3MB
Supplementary Methods, Figure Legends 1-6 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 114K
Supplementary Figure 6 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 81K
Supplementary Figure 5 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 59K
Supplementary Figure 2 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 185K
Supplementary Figure 1 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 36K
Supplementary Methods , Figure Legends 1-5 from Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma
Authors: Chan Isaac S. , Guy Cynthia D. , Chen Yuping , Lu Jiuyi , Swiderska-Syn Marzena , Michelotti Gregory A. , Karaca Gamze , Xie Guanhua , Krüger Leandi , Syn Wing-Kin , Anderson Blair R. , Pereira Thiago A. , Choi Steve S. , Baldwin Albert S. , Diehl Anna Mae
Published: April 2023

PDF file - 82K
Supplementary Video 4 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

MOV file - 3MB, Video for the mice receiving both flavopiridol and obatolcax (day 120 after tumor cell injection via tail vein)
Supplementary Video 3 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

MOV file - 9.5MB, Video for the mice receiving obatolcax (day 120 after tumor cell injection via tail vein)
Supplementary Video 2 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

MOV file - 4.3MB, Video for the mice receiving flavopiridol (day 90 after tumor cell injection via tail vein)
Supplementary Table 1 from Translation Initiation Factor eIF4E Is a Target for Tumor Cell Radiosensitization
Authors: Hayman Thomas J. , Williams Eli S. , Jamal Muhammad , Shankavaram Uma T. , Camphausen Kevin , Tofilon Philip J.
Published: April 2023

PDF file - 113K, List of 1124 genes whose binding to eIF4E was induced by radiation
Supplementary Figure 3 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

PDF file - 163K, FP/obatoclax up-regulates the BH3-only proteins Bim, Noxa, and Bik/NBK, primary events for interaction between FP and obatoclax
Supplementary Methods from Exploiting the Mutanome for Tumor Vaccination
Authors: Castle John C. , Kreiter Sebastian , Diekmann Jan , Löwer Martin , van de Roemer Niels , de Graaf Jos , Selmi Abderraouf , Diken Mustafa , Boegel Sebastian , Paret Claudia , Koslowski Michael , Kuhn Andreas N. , Britten Cedrik M. , Huber Christoph , Türeci Özlem , Sahin Ugur
Published: April 2023

PDF file - 101K
Supplementary Figure Legends 1-7 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: April 2023

PDF file - 36K
Supplementary Figure 7 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: April 2023

PDF file - 522K, RAD18 is not required for RAD51 assembly at DSB sites in the absence of BRCA1 and 53BP1
Supplementary Data 1-6 from Cardiac Inflammation after Local Irradiation Is Influenced by the Kallikrein-Kinin System
Authors: Sridharan Vijayalakshmi , Tripathi Preeti , Sharma Sunil K. , Moros Eduardo G. , Corry Peter M. , Lieblong Benjamin J. , Kaschina Elena , Unger Thomas , Thöne-Reineke Christa , Hauer-Jensen Martin , Boerma Marjan
Published: April 2023

PDF file - 82K, Echocardiography analysis at 3 months and 6 months after local heart irradiation
Supplementary Figure 1 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: April 2023

PDF file - 121K, A schematic of the assembly of DNA damage response-related proteins at DSB sites
Supplementary Figure Legends 1-9 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Authors: Laurent Julien , Hull Eveline Faes-van't , Touvrey Cedric , Kuonen François , Lan Qiang , Lorusso Girieca , Doucey Marie-Agnès , Ciarloni Laura , Imaizumi Natsuko , Alghisi Gian Carlo , Fagiani Ernesta , Zaman Khalil , Stupp Roger , Shibuya Masabumi , Delaloye Jean-François , Christofori Gerhard , Ruegg Curzio
Published: April 2023

Supplementary Figure Legends 1-9 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Supplementary Figure 2 from S-Glutathionylated Serine Proteinase Inhibitors as Plasma Biomarkers in Assessing Response to Redox-Modulating Drugs
Authors: Grek Christina L. , Townsend Danyelle M. , Uys Joachim D. , Manevich Yefim , Coker Woodrow J. , Pazoles Christopher J. , Tew Kenneth D.
Published: April 2023

PDF file - 5MB
Supplementary Movie 1 from Interstitial Fluid Pressure and Associated Lymph Node Metastasis Revealed in Tumors by Dynamic Contrast-Enhanced MRI
Authors: Hompland Tord , Ellingsen Christine , Øvrebø Kirsti Marie , Rofstad Einar K.
Published: April 2023

MOV file - 305K, Video showing the outward movement of the peritumoral high-signal-intensity rim of a TS-415 cervical carcinoma xenograft
Supplementary Table 2 from Gliomagenesis Arising from Pten- and Ink4a/Arf-Deficient Neural Progenitor Cells Is Mediated by the p53-Fbxw7/Cdc4 Pathway, Which Controls c-Myc
Authors: Kim Hong Sug , Woolard Kevin , Lai Chen , Bauer Peter O. , Maric Dragan , Song Hua , Li Aiguo , Kotliarova Svetlana , Zhang Wei , Fine Howard A.
Published: April 2023

PDF file, 345K, Tumors and p53 mutations. All tumors contained one of two different types of p53 mutations (Cys132Trp and Arg270Cys).
Supplementary Materials and Methods from Gliomagenesis Arising from Pten- and Ink4a/Arf-Deficient Neural Progenitor Cells Is Mediated by the p53-Fbxw7/Cdc4 Pathway, Which Controls c-Myc
Authors: Kim Hong Sug , Woolard Kevin , Lai Chen , Bauer Peter O. , Maric Dragan , Song Hua , Li Aiguo , Kotliarova Svetlana , Zhang Wei , Fine Howard A.
Published: April 2023

PDF file, 117K
Supplementary Figure 5 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: April 2023

PDF file - 995K, Comparison of primary versus secondary Wnt(high) CT-2 tumor xenografts
Supplementary Figure 5 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: April 2023

PDF file - 3704K, The vessel normalization effect of NEMs is independent of tumor size. B16.F10 tumors were inoculated in mice, which were then injected at days 11 and 13 after tumor inoculation with PBS, Gr1+ cells and NEMs. Mice were sacrificed when tumors reached 1700 mm3 , irrespective of the day. A. Immunofluorescence analysis of the vasculature - representative images. Frozen sections were stained with antibodies against CD31 (green) and α-SMA (red).Nuclei are counterstained with DAPI. Scale bar: 100 μm. B. Quantitative evaluation of the α-SMA/CD31 ratio in vessels of tumors injected with PBS, Gr1+ cells or NEMs. Data are mean�s.e.m. **=P<0.01 vs. PBS.
Supplementary Figure 3 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: April 2023

PDF file - 1471K, Levels of expression of plexins in CD11b+ Gr1+ Nrp1+ cells and in NEMs. Real-time PCR quantifications were normalized to the levels of GAPDH mRNA. Data are mean �s.e.m. **=P<0.01; *=P<0.05.
Supplementary Figure 2 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 2.2MB, (A) Cell monolayers were infected with 100 viral paticles /cell (VP/cell) and 24 hours later cells were analyzed by flow-cytometry measuring Annexin-V expression. Results are presented as percentage of positive cells relative to Mock uninfected cells. **, P<0.01. (B) CD40 expression is shown in brown in A549 and EJ tumors. Pictures were taken with an Axioplan Microscope equipped with a camera Axiocam at a magnification of 10x. (C) Tumors from nude mice bearing either A549 tumors (left panel) or EJ tumors (right panel) injected with viruses were analyzed for viral load. Quantitative PCR was performed for E4 sequence and values were normalized to human beta-actin gene.. The real-time PCR conditions were as described in (31). All samples were tested in duplicate. Results are presented as mean from all mice +SEM. **, P<0.01.
Supplementary Figure 4 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 11564K, MMP-1 is able to rescue defects in spheroid outgrowth resulting from TWIST1 ablation
Supplementary Figure 3 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 1651K, Absence of EMT-like protein changes following altered TWIST1 expression in melanoma cells
Supplementary Table 2 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages
Authors: Osawa Tsuyoshi , Tsuchida Rika , Muramatsu Masashi , Shimamura Teppei , Wang Feng , Suehiro Jun-ichi , Kanki Yasuharu , Wada Youichiro , Yuasa Yasuhito , Aburatani Hiroyuki , Miyano Satoru , Minami Takashi , Kodama Tatsuhiko , Shibuya Masabumi
Published: April 2023

PDF file - 38K, List of genes up- and down-regulated in response to hypoxia and nutrient starvation double stress (DDS) in human cancer cells.
Supplementary Table 1 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages
Authors: Osawa Tsuyoshi , Tsuchida Rika , Muramatsu Masashi , Shimamura Teppei , Wang Feng , Suehiro Jun-ichi , Kanki Yasuharu , Wada Youichiro , Yuasa Yasuhito , Aburatani Hiroyuki , Miyano Satoru , Minami Takashi , Kodama Tatsuhiko , Shibuya Masabumi
Published: April 2023

PDF file - 37K, The sequence of specific primers for angiogenic factors and JMJD1A in real-time polymerase chain reaction analysis.
Supplementary Data from ErbB3 Ablation Impairs PI3K/Akt-Dependent Mammary Tumorigenesis
Authors: Cook Rebecca S. , Garrett Joan T. , Sánchez Violeta , Stanford Jamie C. , Young Christian , Chakrabarty Anindita , Rinehart Cammie , Zhang Yixian , Wu Yaming , Greenberger Lee , Horak Ivan D. , Arteaga Carlos L.
Published: April 2023

Supplementary Figures S1-S3; Supplementary Methods.
Supplementary Figure 3 from miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
Authors: Kasinski Andrea L. , Slack Frank J.
Published: April 2023

PDF file - 349K, As shown in all of the sections obtained from the pretreatment study, miR-34 prevents Kras;p53-induced tumorigenesis.
Supplementary Table S4 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Authors: Ishii Nobuya , Harada Naoki , Joseph Eric W. , Ohara Kazuhiro , Miura Takaaki , Sakamoto Hiroshi , Matsuda Yutaka , Tomii Yasushi , Tachibana-Kondo Yukako , Iikura Hitoshi , Aoki Toshihiro , Shimma Nobuo , Arisawa Mikio , Sowa Yoshihiro , Poulikakos Poulikos I. , Rosen Neal , Aoki Yuko , Sakai Toshiyuki
Published: April 2023

Supplementary Table S4 - PDF file 56K, Binding constant between MEK1 and BRAF or CRAF, related to Figure 3. His6-MEK1 binding to immobilized GST-BRAF or GST-CRAF in the presence of 500 �M ATP, 500 �M ATP plus 3 �M CH5126766 or 500 �M ATP plus 3 �M PD0325901 were analyzed with SPR
Supplementary Figure 3 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: April 2023

PDF file - 60K, Immunostaining of PEG-encapsulated structures following TGFbeta treatment shows loss of polar organization and cells undergo random apoptosis and proliferation
Supplementary Figures 6 - 8 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: April 2023

PDF file, 533K, Supplementary Figure S6. Analysis of MiR-10b and MiR-196b and HOXD10 in Dicerflox/flox:Id1pr/p-CreERT2 BMT mice. Supplementary Figure S7. MiRNA Expression in Tumor Vasculature using mCherry Exclusion. Supplementary Figure S8. ISH Analysis of miR-10b Expression in Normal and Tumor Vasculature.
Supplementary Figures 1 - 5 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: April 2023

PDF file, 510K, Supplementary Figure S1. Conditional Ablation of DICER in the BM. Supplementary Figure S2. Retroviral Delivery of CRE-Recombinase. Supplementary Figure S3. Analysis of Dicerflox/flox:Id1pr/p-CreERT2 BMT animals. Supplementary Figure S4. Representative Scatter Plots of EPC Isolation and Analysis by FACS. Supplementary Figure S5. ISH Analysis of MiR-10b Expression in EPCs.
Supplementary Figure 12 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: April 2023

PDF file, 149K, Supplementary Figure S12. RGD Peptide Directed Delivery of Anti-miRs using Liposomes.
Supplementary Table 1 from Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells
Authors: Chen Ke , Wu Kongming , Cai Shaoxin , Zhang Wei , Zhou Jie , Wang Jing , Ertel Adam , Li Zhiping , Rui Hallgeir , Quong Andrew , Lisanti Michael P. , Tozeren Aydin , Tanes Ceylan , Addya Sankar , Gormley Michael , Wang Chenguang , McMahon Steven B. , Pestell Richard G.
Published: April 2023

PDF file - 38K, Supplemental Table 1. Genes binding both P53 and DACH1 in ChIP Seq.
Supplementary Figure 2 from Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
Authors: Muthana Munitta , Rodrigues Samuel , Chen Yung-Yi , Welford Abigail , Hughes Russell , Tazzyman Simon , Essand Magnus , Morrow Fiona , Lewis Claire E.
Published: April 2023

PDF file - 426K, Macrophage delivery of an oncolytic virus (Ad1/PPT-E1A) abolishes the regrowth of prostate (LUC-LNCaP) tumors following irradiation
Supplementary Tables 1 - 4 from Impact of Body Mass Index on the Risk of Colorectal Adenoma in a Metabolically Healthy Population
Authors: Yun Kyung Eun , Chang Yoosoo , Jung Hyun-Suk , Kim Chan-Won , Kwon Min-Jung , Park Sung Keun , Sung Eunju , Shin Hocheol , Park Hye Soon , Ryu Seungho
Published: April 2023

PDF file - 155K, Associations between body mass index and colorectal polyps in 18,085 metabolically healthy participants among health checkup examinees at Kangbuk Samsung Hospital in 2010-2011 (S1); Associations between body mass index and colorectal polyps by gender in 18,085 metabolically healthy participants among health checkup examinees at Kangbuk Samsung Hospital in 2010-2011 (S2); Associations between body mass index and colorectal polyps in 41,192 participants among health checkup examinees at Kangbuk Samsung Hospital in 2010-2011 without excluding those with metabolically unhealthy status (S3); Associations between body mass index and colorectal polyps by gender in 41,192 participants among health checkup examinees at Kangbuk Samsung Hospital in 2010-2011 without excluding those with metabolically unhealthy status (S4).
Supplementary Figure 7 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 50K, Xpf and Mus81 are compensatory to each other in the completion of HR in human and mouse cell lines.
Supplementary Tables from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 109K, Clonogenic survival of lung SqCC after radiation (S1); High-throughput profiling of lung SqCC after radiation (S2); Mutations in NFE2L2 and KEAP1 in lung SqCC cell lines (S3); MSigDB Gene Sets from Fig S5 (S4); TP53 alterations, LOH, and mRNA levels in lung SqCC cell lines (S5).
Supplementary Figure 4 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 103K, NFE2L2 is frequently activated in human cancers.
Supplementary Table 1 from Loss of ARF Sensitizes Transgenic BRAFV600E Mice to UV-Induced Melanoma via Suppression of XPC
Authors: Luo Chi , Sheng Jinghao , Hu Miaofen G. , Haluska Frank G. , Cui Rutao , Xu Zhengping , Tsichlis Philip N. , Hu Guo-Fu , Hinds Philip W.
Published: April 2023

PDF file - 23K, Primer sequences.
Supplementary Figure 1 from Loss of ARF Sensitizes Transgenic BRAFV600E Mice to UV-Induced Melanoma via Suppression of XPC
Authors: Luo Chi , Sheng Jinghao , Hu Miaofen G. , Haluska Frank G. , Cui Rutao , Xu Zhengping , Tsichlis Philip N. , Hu Guo-Fu , Hinds Philip W.
Published: April 2023

PDF file - 155K, Tumor formation in BRAFV600E/ARF-/- mice.
Supplementary Figure 1 from MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells
Authors: Stroopinsky Dina , Rosenblatt Jacalyn , Ito Keisuke , Mills Heidi , Yin Li , Rajabi Hasan , Vasir Baldev , Kufe Turner , Luptakova Katarina , Arnason Jon , Nardella Caterina , Levine James D. , Joyce Robin M. , Galinsky Ilene , Reiter Yoram , Stone Richard M. , Pandolfi Pier Paolo , Kufe Donald , Avigan David
Published: April 2023

PDF file, 3013K, AML blasts from patient #20 harbored the trisomy 14 chromosomal abnormality.
Supplementary Table 2 from A Novel Model for Evaluating Therapies Targeting Human Tumor Vasculature and Human Cancer Stem–like Cells
Authors: Burgos-Ojeda Daniela , McLean Karen , Bai Shoumei , Pulaski Heather , Gong Yusong , Silva Ines , Skorecki Karl , Tzukerman Maty , Buckanovich Ronald J.
Published: April 2023

PDF File - 71K, PCR primers used.
Supplementary Methods from Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
Authors: Zhang Yaqing , Yan Wei , Collins Meredith A. , Bednar Filip , Rakshit Sabita , Zetter Bruce R. , Stanger Ben Z. , Chung Ivy , Rhim Andrew D. , di Magliano Marina Pasca
Published: April 2023

PDF file - 139K, Includes tables of antibodies and PCR primers and detailed methods for common procedures.
Supplementary Figure 6 from Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
Authors: Zhang Yaqing , Yan Wei , Collins Meredith A. , Bednar Filip , Rakshit Sabita , Zetter Bruce R. , Stanger Ben Z. , Chung Ivy , Rhim Andrew D. , di Magliano Marina Pasca
Published: April 2023

PDF file - 184K, MAPK and IL6 signaling pathways activity following Kras* inactivation.
Supplementary Figure 1 from Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
Authors: Zhang Yaqing , Yan Wei , Collins Meredith A. , Bednar Filip , Rakshit Sabita , Zetter Bruce R. , Stanger Ben Z. , Chung Ivy , Rhim Andrew D. , di Magliano Marina Pasca
Published: April 2023

PDF file - 221K, IL6 is up-regulated in pancreatic cancer and required for PanIN formation.
Supplementary Figures from Indirubin Derivative 6BIO Suppresses Metastasis
Authors: Braig Simone , Kressirer Christine A. , Liebl Johanna , Bischoff Fabian , Zahler Stefan , Meijer Laurent , Vollmar Angelika M.
Published: April 2023

PDF file, 59K, S1. Reduced attachment of 6BIO treated T24 cells as determined by xCELLigence experiments (left). DMSO treated cells served as control. S2. Representative images of scratch assays of T24 cells treated with 6BIO,vMe-6BIO, 5BIO and 7BIO. S3. Chemical structures of 5BIO, 6BIO, Me-6BIO and 7BIO. S4. Treatment of HuH-7 hepatocellular cancer cells, MDA-MB-231 and 4T1 breast cancer cell lines with 3microM 6BIO strongly reduced the migratory potential, as shown by wound healing assays. S5. Representative images of filter areas counted in the Boyden chamber assays described in Figure 1D. S6. Boyden chamber assays revealed no inhibition of migration after treatment of T24 cells with the CDK-inhibitor Roscovitine. S7. No induction of apoptosis was observed after treatment of T24 cells with 10mM LiCl, 10microM Roscovitine, 10microM GSK2334470, 1microM Saracatinib and 10microM Jak-Inhibitor I for 48h, as determined by FACS assays. S8. Inhibiting Jak1, PDK1 or GSK3� using specific siRNAs or a combination of them has no influence on apoptosis (A) or proliferation (B) of T24 cells. Table S1. Nicoletti assays revealed no induction of apoptosis after treatment of HuH- 7, MDA-MB-231 and 4T1 cells with low concentrations of 6BIO.
Supplementary Figures 1 -2 from Vaccine-Instructed Intratumoral IFN-γ Enables Regression of Autochthonous Mouse Prostate Cancer in Allogeneic T-Cell Transplantation
Authors: Hess Michelini Rodrigo , Manzo Teresa , Sturmheit Tabea , Basso Veronica , Rocchi Martina , Freschi Massimo , Listopad Joanna , Blankenstein Thomas , Bellone Matteo , Mondino Anna
Published: April 2023

PDF - 152K, Supplementary Figure 1: CD4+ and CD8+ T cells infiltrate the stroma and the transformed epithelium following transplantation and vaccination.) Supplementary Figure 2: Tumor-directed vaccination and alloreactive DLI synergize in evoking intratumoral infiltration.
Supplementary Figure 7 from SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma
Authors: Bareiss Petra M. , Paczulla Anna , Wang Hui , Schairer Rebekka , Wiehr Stefan , Kohlhofer Ursula , Rothfuss Oliver C. , Fischer Anna , Perner Sven , Staebler Annette , Wallwiener Diethelm , Fend Falko , Fehm Tanja , Pichler Bernd , Kanz Lothar , Quintanilla-Martinez Leticia , Schulze-Osthoff Klaus , Essmann Frank , Lengerke Claudia
Published: April 2023

PDF file, 89K, SOX2 expression inhibits caspase-3 processing in response to apoptotic agents.
Supplementary Figure 3 from SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma
Authors: Bareiss Petra M. , Paczulla Anna , Wang Hui , Schairer Rebekka , Wiehr Stefan , Kohlhofer Ursula , Rothfuss Oliver C. , Fischer Anna , Perner Sven , Staebler Annette , Wallwiener Diethelm , Fend Falko , Fehm Tanja , Pichler Bernd , Kanz Lothar , Quintanilla-Martinez Leticia , Schulze-Osthoff Klaus , Essmann Frank , Lengerke Claudia
Published: April 2023

PDF file, 58K, Analysis of primary SOC cells transduced with SOX2-overexpressing and control lentiviruses.
Supplementary Movie 1 from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

AVI file - 503K, Time-lapse video-recording of a representative JVM3 cells exposed to a CCL19 gradient (source of CCL19 towards the bottom) over a period of 5 min.
Supplementary Methods from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

PDF file - 54K, Additional information regarding CCR7 internalization.