bluuebunny/crossref_metadata_2025 huggingface dataset:
Low Performance of Hepatitis Delta Virus Testing Among 2 National Cohorts of Chronic Hepatitis B Patients in the United States
Authors: Wong Robert J. , Kaufman Harvey W. , Niles Justin K. , Chen Cheng , Yang Zeyuan , Kapoor Hema , Cheung Ramsey , Gish Robert G.
Published: August 2022

INTRODUCTION:

The purpose of this study was to evaluate hepatitis delta virus (HDV) testing patterns among US adults with chronic hepatitis B (CHB).

METHODS:

HDV testing was evaluated among CHB patients using Quest Diagnostics (2016–2020) and Veterans Affairs (2010–2020) data.

RESULTS:

Among 157,333 CHB patients (Quest), 6.7% received HDV testing, among which 2.2% were positive. HDV testing was higher in male patients, younger individuals, and patients with advanced liver disease. Among 12,002 CHB patients (Veterans Affairs), 19.7% received HDV testing, among which 3.1% were positive. HDV testing was higher in younger individuals and Asians.

DISCUSSION:

Low HDV testing was observed among 2 large US cohorts of adults with CHB.
Análise dos Parâmetros Morfométricos da Rede de Drenagem e Rede Viária da Bacia Hidrográfica do Ribeirão Paraíso, Jataí-GO
Authors: Souza Carine Cabral , Cunha Márcia Cristina
Published: August 2022

Estudos referentes à análise morfométrica são de extrema importância para o conhecimento hidrogemorfológico em bacias hidrográficas. Contudo, as estradas rurais, em sua maioria, não são consideradas nessas análises. Sendo assim, o objetivo deste artigo foi verificar se as relações entre rede de drenagem, os parâmetros de relevo e rede de viária indicam mudanças na dinâmica de drenagem de uma bacia hidrográfica ocupada por uso agrícola. A cultura da cana-de-açúcar é um fator de influência no aumento das estradas rurais na bacia e chegou na região a partir de 2009. Portanto, optou-se pelo recorte temporal de 2005, 2010, 2015 e 2020 para a investigação. Como metodologia, utilizou-se a pesquisa bibliográfica e as medidas quantitativas para extração de informações de rede de drenagem e rede viária por meio de parâmetros morfométricos. Para isso, foram utilizados os softwares ArcGIS® 10.6.1 e Excel 2019. Como resultados, identificou-se que a bacia apresenta hierarquia fluvial de quarta ordem, sua área é de 903,6 km², a densidade de drenagem é de 0,45 km/km² e quando inseridas as estradas rurais na análise, em (2005) correspondeu à 2,1km/km², (2010) 2,2km/km², (2015) 2,4km/km², e em (2020) 3,1km/km². Sendo assim, a média da densidade de estradas no período foi 84% superior quando se considerou apenas a drenagem natural, aumentando principalmente depois da inserção da cana-de-açúcar no cenário. Conclui-se, portanto, que a análise de parâmetros morfométricos é primordial para gerar novos conhecimentos sobre a bacia estudada, e as estradas rurais devem ser incluídas nas análises, uma vez que influenciam os aspectos hidrogeomorfológicos das bacias. Nesse caso, o aumento da densidade de drenagem está diretamente relacionado ao aumento das estradas e cana-de-açúcar, e com a inclusão destas na análise morfométrica, a bacia aumenta sua capacidade de drenagem, alterando de forma significativa a resposta hidrológica em bacias hidrográficas.
Vector correlation learning and pairwise optimization feature selection for false data injection attack detection in smart grid
Authors: Xing Ziya , Liu Boyu
Published: August 2022

This paper mainly studies vector-related learning and pairwise optimization feature selection for false data injection attack detection in smart grid. In order to provide experimental detection of false data injection attacks, this article will conduct a detailed analysis of the power system segmentation. This paper comprehensively considers the similarity of nodes, security control and confidentiality strategies to complete the optimal partition. Next, we preprocess the measurement data. In order to improve the adaptability of the algorithm structure to the grid structure and further improve the accuracy and convergence speed of the algorithm output, a differential evolution algorithm with swarm intelligence is proposed. Obtain a higher-precision state estimate useful for detecting bad data. In the experiment of this article, if false data account for 20% of all data, the detection accuracy exceeds 75%. As the number of experimental groups increases, the detection accuracy of only one type of false data that does not meet the rules will continue to increase, but the detection accuracy of other types of false data will not change much, but the overall detection accuracy will become higher. Experimental results show that the detection framework can not only effectively detect and identify false data injection attacks on multiple bus nodes, but also has high detection accuracy and can effectively recover false data.
Effect of metal layer height on heat transfer inside molten pool
Authors: Liu Chang , Ma Pengfei , Liu Hui , Liu Yan , Zhao Danting , Lei Yudian , Zhou Yuxuan , Xue Jiyuan , Huang Zijing , Cao Liuxuan
Published: August 2022

In a serious accident, after the core of a nuclear reactor melts and collapses, In-Vessel Retention in the External Reactor Vessel Cooling (IVR-ERVC) is an effective technology to maintain the integrity of lower head by reducing heat load on it. The various factors affecting the melting of the lower head have been widely studied. The mass of the molten metal layer may affect the consequences of the accident, since it is where the focusing effect occurs. However, the related research is still absent. In this paper, we systematically calculated the heat transfer behavior and melting process under different metal layer heights conditions. The temperature distribution, the velocity distribution, the heat flux of the outer wall of the Reactor Pressure Vessel (RPV), and the change of the thickness of the RPV were obtained through Large Eddy Simulation (LES). Interestingly, the heat flux increases with the metal layer height at first and achieve the maximum in the middle height. These results increase the understanding towards the serious accidents.
Automated assessment of immunofixations with deep neural networks
Authors: Thiemann Christian , Klitzke Britta , Martinetz Philipp , Grüning Philipp , Käster Thomas , Barth Erhardt , Kramer Jan , Martinetz Thomas
Published: August 2022

Objectives

The reliable evaluation of immunofixation electrophoresis is part of the laboratory diagnosis of multiple myeloma. Until now, this has been done routinely by the subjective assessment of a qualified laboratory staff member. The possibility of subjective errors and relatively high costs with long staff retention are the challenges of this approach commonly used today.

Methods

Deep Convolutional Neural Networks are applied to the assessment of immunofixation images. In addition to standard monoclonal gammopathies (IgA-Kappa, IgA-Lambda, IgG-Kappa, IgG-Lambda, IgM-Kappa, and IgM-Lambda), also bi- or oligoclonal gammopathies, free chain gammopathies, non-pathological cases, and cases with no clear finding are detected. The assignment to one of these 10 classes comes with a confidence value.

Results

On a test data set with over 4,000 images, approximately 25% of the cases are sorted out as inconclusive or due to low confidence for subsequent manual evaluation. On the remaining 75%, about 3,000 cases, not even one is classified as falsely positive, and only one as falsely negative. The remaining few deviations of the automated assessment from the classifications assigned manually by experts are borderline cases or can be explained otherwise. As a software running on a standard desktop computer, the Deep Convolutional Neural Network needs less than a second for the assessment of an immunofixation image.

Conclusions

Assisting the laboratory expert in the assessment of immunofixation images can be a useful addition to laboratory diagnostics. However, the decision-making authority should always remain with the physician responsible for the findings.
Two isomers Ba5Mg4C54O48H114 and Pb5Mg4C54O48H114
Authors: Fábry Jan , Samolová Erika , Dušek Michal
Published: August 2022

There are reported two related structures of Ba5Mg4C54O48H114 (dodeca(aqua-6κ
3O,7κ
3O,8κ
3O,9κ
3O)-tris(μ2-propanoato-1:6κ
2O,1κO′)-tris(μ-propanoato-2:7κ
2O,2κO′-tris(μ-propanoato-3:8κ
2O,3κO′)-tris(μ-propanoato-4:9κ
2O,4κO′)-hexakis(μ3-propanoato-1:5κ
2O,2:5κ
2O′;1:5κ
2O,3:5κ
2O′;1:5κ
2O,4:5κ
2O′;2:5κ
2O,3:5κ
2O′;2:5κ
2O,4:5κ
2O′;3:5κ
2O,4:5κ
2O′)-pentabarium tetramagnesium), (I), and Pb5Mg4C54O48H114 (dodeca(aqua-1κ
3O,2κ
3O,3κ
3O,4κ
3O)-hexakis(μ3-propanoato-1:5κ
2O,2:5κ
2O′;1:5κ
2O,3:5κ
2O′;1:5 κ
2O,4:5κ
2O′;2:5κ
2O,3:5κ
2O′;2:5κ
2O,4:5κ
2O′;3:5κ
2O,4:5κ
2O′)tetramagnesium lead(II) tris(propanoato-κ
2O,O′)plumbate(II)), (II). The title structures are compositional isomers which crystallize in the same space group type. The structure of (I) comprises molecules with symmetry 

4
‾

3
m

$\overline{4}3m$

. The structure (II) comprises the complex cation {Pb(C3H5O2)6[Mg(H2O)3]4}4+ with the symmetry

4
‾

3
m

$\overline{4}3m$

and four anions [tris(propanoato-κ
2O,O′)plumbate(II)]−, [Pb(C3H5O2)3]− , with 3m symmetry. The central cations Ba12+ and Pb12+ in (I) and in the cation {Pb(C3H5O2)6[Mg(H2O)3]4}4+ of the structure (II), respectively, have similar structural features which are comparable to the environment of the Ba2+ cation in BaCa2(C3H5O2)6 [Stadnicka, K. & Glazer, A. M. (1980). Acta Cryst. B36, 2977–2985]. The molecules in (I) and the ions in (II) are interconnected by Owater‒H⋯Opropanoate hydrogen bonds of a moderate strength. The ethyl chains are disordered which is common in propanoates. However, there are unprecedented features in the title structures: 1) The central atom Pb12+ is the first known example of a Pb2+ cation which is surrounded by six carboxylates in a bidentate bridging mode, i.e. by 12 oxygens. 2) The anion [tris(propanoato-κ
2O,O′)plumbate(II)]− has a constitution with unusually prominent stereochemical activity of the 6s
2 electron pair of the cation Pb2+ completing the coordination to the tetrahedral one. Thus, its formula can be expressed as [Pb[ψ−4t](C3H5O2)3]−. 3) In both title structures, there are propanoate molecules with disordered carboxylate oxygens.
Preparation and comparative evaluation of PVC/PbO and PVC/PbO/graphite based conductive nanocomposites
Authors: Raza Junaid , Hamid Abdul , Khan Muhammad , Hussain Fakhar , Zada Amir , Tiehu Li , Ali Amjad , Fazil Perveen , Wahab Zainul
Published: August 2022

Two series, A and B, of PVC based nanocomposite polymer membranes (nCPMs) were prepared using PbO only and PbO/graphite mixture as a filler by solution casting method. Seven samples with varying compositions (5–35%) of filler particles were prepared for each series and were compared by thickness measurements, porosity, water uptake, swelling degree, ionic conductivity, ion exchange capacity (IEC), membrane potential and transport number. The maximum values for these characteristics were observed as 0.402 mm, 0.77, 141.3%, 0.11, 0.0033 Scm−1, 8.6 milli-eq.g−1, 0.19 V and 0.01391 for series-A composites whereas that of 0.367 mm, 0.83, 63.4%, 0.019, 0.00981 Scm−1, 5.21 milli-eq.g−1, 0.13 V and 0.0108 for series-B nCPMs respectively. The SEM images of membranes showed greater voids produced in the series-B compared to series-A composites. The maximum Ionic conductivity, IEC, membrane potential and transport number were observed for membrane with 25% PbO/graphite, 20% PbO and 35% PbO particles respectively.
A comparative study of apricot kernel oil yield using different extraction methods
Authors: Hao Yinan , Wang Jingwen , Qi Lin , Qiu Yilong , Liu Hui , Zhang Yongqiang , Wang Ximing
Published: August 2022

Apricot kernel was used as a raw material to compare and analyze the yield of apricot kernel oil using a pressing method, an ultrasonic-assisted extraction method, and a Soxhlet extraction method. The optimum extraction conditions were further verified through gas chromatography-mass spectrometry (GC-MS), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The fatty acid composition of the apricot kernel oil consisted of palmitic acid and stearic acid, and the total content of cis-oleic acid and cis-linolenic acid reached 93%. The apricot kernel oil obtained by Soxhlet extraction had the highest yield. However, the Soxhlet method has some limitations, such as high consumption of energy, long extraction time, and low efficiency. Ultrasound-assisted extraction has been developed by the industry to minimize these disadvantages. Finally, nuclear magnetic resonance (NMR) analysis was carried out on the ultrasonic-assisted extraction method, and it was again shown that the apricot kernel oil contained many unsaturated fatty acids.
The variance of word-forming suffixes in conversational person names based on external features
Authors:   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Horodensʹka Kateryna
Published: August 2022

This article addresses the issue of quantitative and qualitative manifestations of variance of wordforming suffixes in the names of persons motivated by noun names of the body parts and adjective names of some of the external excessive corporeal markers. For the first time, the paper ascertains historically formed and the most complete composition of specific noun suffixes leading to the rise of the equivalent and mostly cognate names of persons with respect to actualized external features of their body. The author discusses the ability of all names of human body parts and some names of corporeal external qualitative features to be combined with the different number of word-forming suffixes within the common word-forming meaning which allows for forming six-, four-, three-, and two-variant series. In this paper, І determine the actualized feature each variant series is based on, indicate a number of its variant suffixes, and account for their ratio in terms of productivity and functional and stylistic use. The main hypothesis is that it is the stylistically reduced nature of variant names of persons based on appearance which led to their predominant use in the colloquial usage and language of Ukrainian fiction. As a necessary part of the account, we provide evidence from literary works in Ukrainian translations which attest to a noticeable intensification in the above-mentioned names use. A rather broad reflection of these variant appellatives in Ukrainian surnames shows a characteristic feature of Ukrainian mentality, namely the differentiation of the outside world subjects due to the preferred corporeal related markers. Keywords: variance of word-forming suffixes, names of persons by external features, variant series, common names, surnames
Studies in historical linguistics at the Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine
Authors:   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Puriaieva Nataliіa , Kotsa Ruslana ,   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine, Babenchuk Bohdana ,   Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine
Published: August 2022

This article analyzes major directions, achievements, and prospects of studies in historical linguistics accomplished by the department of the history of Ukrainian of the Institute of the Ukrainian Language of the National Academy of Sciences of Ukraine within 30 years since its foundation. The department has focused on the Ukrainian glotogenesis and dialectogenesis and their ProtoSlavic origins, the history and structure of Church Slavonic in its East Slavic recension as attested in Old Ukrainian records and used on the Ukrainian ethnolinguistic territory in the 10th—13th centuries, and the history of the Ukrainian orthography. At the moment, three general research areas are in the center of scholarly interests, which are editorial studies of linguistics sources, historical lexicography, and the academic history of Ukrainian. Together with the historians of language working at different Ukrainian educational institutions and research centers, the department continues publishing the book series Ukrainian Written Records of the 11th—13th centuries. In 2019, the department coordinated a scientific seminar series dealing with the historical and lexicographic project Dictionary of the Ukrainian Language of the Late 17th—18th Century. It starts working on a monograph to present theoretical and methodological principles of the dictionary ompilation. Together with the South Ukrainian Historical Word Formation Center (founded in 2004, Zaporizhzhia), the department is working on the 5th volume of the academic book A History of the Ukrainian Language. Word Formation containing a generalized study of word formation of the nominative elements of Ukrainian. Keywords: historical and linguistic research, editorial studies of linguistic sources, historical lexicography, historical word formation
Evaluasi Settling Pond pada Area Run of Mine (ROM)
Authors: Parhusip Masjon , Ernawati Rika , Cahyadi Tedy Agung
Published: August 2022

Kualitas air akibat terkontaminasi oleh batubara  akan membentuk larutan  yang bersifat asam , sehingga perlu dilakukan penanganan terlebih dahulu sebelum di alirkan ke sungai. Tujuan penelitian ini adalah mengevaluasi settling pond dengan menentukan curah hujan rencana menggunakan distribusi gumbell dan menghitung debit air limpasan dengan menggunakan metode rasional. Data curah hujan yang digunakan merupakan data 10 tahun (2010-2020). Dari hasil penelitian diketahui nilai curah hujan rencana dengan perhitungan distribusi gumbell untuk periode ulang 5 Tahun adalah 39,4 mm/jam, sehingga perhitungan dengan metode rasional diketahui Debit air limpasan adalah 13.110,98 m3/jam. Perhitungan dimensi geometri settling pond dapat menampun debit air limpasan 12.852 m3. Pada makalah ini, penulis merekomendasikan pembuatan saluran terbuka dengan membagi catchment area I dan II. Diharapkan debit air limpasan pada catchment area I yang tidak terkontaminasi oleh tumpukan batubara langsung mengalir ke sungai kecil. Dari rekomendasi tersebut memberikan nilai debit air limpasan pada catchment area II  menjadi  11.001,39 m3/jam. Sehingga settling pond dapat menampung debir air larian yang terkontaminasi oleh batubara pada catchment area II.
COX-2 upregulation by tumour cells post-chemotherapy fuels the immune evasive dark side of cancer inflammation
Authors: Bell Charlotte R. , Zelenay Santiago
Published: August 2022

Cytotoxic therapies, such as chemotherapy and radiotherapy, are mainstays of cancer treatment for both early and unresectable, advanced disease. In addition to debulking the tumour mass through direct killing of pro-liferating tumour cells, these treatments can promote tumour control via immune-stimulating effects. Nonetheless, chemoresistance and tumour relapse remain huge clinical problems, suggesting that induction of anti-cancer immunity post-cytotoxic therapy is often weak, not durable and/or overcome by immune evasive mechanisms. In our recent study (Nat Commun 13:2063), we demonstrate that cancer cell-intrinsic activation of the cyclooxygenase (COX)-2/prostaglandin E2 (PGE2) path-way post-chemotherapy treatment is a prevalent phenomenon which profoundly alters the inflammatory properties of the treated cancer cells. Of particular translational relevance, our findings support a model whereby upregulation of COX-2 expression and activity post-chemotherapy impairs the efficacy of the combination of PD-1 blockade and chemotherapy. Accordingly, pharmacological inhibition of COX-2 with celecoxib, an anti-inflammatory drug already used clinically, unleashed tumour control in preclinical models when given alongside chemoimmunotherapy combinations.
Language Competency – Promoting Communicative Approach For Engineering students
Authors: Jaheer Billa
Published: August 2022

In this world of gizmos, particularly with the cut-throat competition existing in the global arena, Communication skills play a key role for global communications. To face the impending future encounters at the workplace and to meet the demands of the organizations the engineering graduates
got to be equipped with excellent communication skills. Name any organization which is considered to be highly reputed is in fact looking for professionals who possess the gift of gab, garrulous and tackle the bottle-necks in the organization with their exceptionally phenomenal communication
and inter-personal skills. The companies like Google and Microsoft are today looking for engineering graduates who not only have technical knowledge and but have immense talent of communicating with the people for official transactions. So the need of the hour is to create the methods and
techniques which would meet the communicative requirements of the engineering graduates. In this paper I am trying to explore the methods which can be implemented and imparted among engineering students to make them viably competent and effective communicators.
Kum Zemindeki Bir Derin Kazının Komşu Kazığın Davranışı Üzerindeki Etkisinin Statik Analizi
Authors: ASHOUR Sameh , ÜNSEVER Yeşim S.
Published: August 2022

The influence of deep excavation on adjacent pile behaviour is an important issue to ensure its serviceability and stability. In this paper, the effect of deep excavation on an adjacent loaded single pile in saturated cohesionless soil was investigated by 3D finite element method. After verification of finite element model using centrifuge test results found in literature, a parametric study was conducted by varying the most influence factors on the pile behaviour such as excavation depth, distance from the pile to the excavation and pile head type. It was concluded that the excavation depth (He) with respect to pile length (Lp) has a significant effect on pile response. Among the three cases of He/Lp, the case of He/Lp= 0.5 induced the maximum bending moment while the case of He/Lp= 1.5 induced the maximum pile lateral deflection. Moreover, the distance from the pile to the excavation site has also a significant influence on pile response and the induced bending moment in pile is inconsiderable after 9 m distance. Also, it is observed that the pile head type has an important effect on the pile behaviour especially in case of rigid head case.
The mediating role of behavioral control on the intention to repurchase halal cosmetics
Authors: MURSID MANSUR CHADI , Palupiningtyas Andita Dwi , Hamid Abdul , Aenurofik Aenurofik
Published: August 2022

The more growth in the cosmetic industry today does not rule out that there are cheats that occur either from the ingredients used or the chemical content contained in cosmetics. In the marketing world there is a theory about consumer behavior in choosing and consuming a product, namely Theory of Planned Behavior (TPB). TPB identifies influences that predict and change behavior, where behavioral intention is influenced by: a person's attitude, beliefs about whether an individual who is important to that person approves or disapproves of the behavior, and perceived control over performing the behavior. The purpose of this study was to determine the effect of consumer attitudes and subjective norms on the intention to repurchase halal cosmetics mediated by behavioral control on as many as 150 college students in Pekalongan with the sampling technique using purposive sampling. The analysis technique used in this research is the Structural Equation Modeling analysis technique with the help of the AMOS version 22 program. This research includes field research with a quantitative approach. Sources of data obtained from primary data and secondary data, while the data in this study were obtained from observations, questionnaires and documentation. Based on the results of the analysis in this study, the results show that (1) consumer attitudes have a positive and significant effect on behavior control, (2) subjective norms have a positive and significant effect on behavior control, (3) consumer attitudes have a positive and significant effect on repurchase interest, (4) subjective norm has a significant positive effect on the intention to repurchase cosmetic products labeled halal, (5) behavioral control has a positive and significant effect on repurchase interest, (6) Behavioral control can mediate the effect of consumer attitudes on consumer repurchase interest in halal cosmetic products , (7) Behavioral control can mediate the effect of subjective norms on consumer repurchase interest in halal cosmetic products.
Viral infections in prostate carcinogenesis: literature review
Authors: Kamalov A. A. , Mikhaleva L. M. , Matveev V. B. , Karpov V. K. , Okhobotov D. A. , Osmanov O. A. , Akopyan E. P. , Shaparov B. M.
Published: August 2022

Prostate cancer is one of the most common malignant diseases in men. Viral infections can be risk factors for prostate carcinogenesis. Based on the literature review, an assumption can be made about the pathogenetic role of viral infections in prostate carcinogenesis. Further study of this problem is required, the solution of which can make a great contribution to the diagnosis and prevention of prostate cancer
Situation with cancer care in Russia. Kidney cancer (median survival, cumulative survival, and survival of patients depending on their disease stage). Population-based study at the federal district level. Part 2
Authors: Merabishvili V. M. , Nosov A. K.
Published: August 2022

Background. In the first part of our study, we described the dynamics of kidney cancer (С64) incidence and mortality, as well as reliability of kidney cancer surveillance in Russia. This study analyzed the effectiveness of cancer control measures in Russia by assessing patient survival using the data form the newly developed Population-based cancer registry of the North-Western Federal District.

Materials and methods. We used the data from the Population-based cancer registry of the North-Western Federal District of Russia that has more than 1,350,000 records, including 35,629 kidney cancer patients. Standard methods of the European Network of Cancer Registries (EUROCARE program) were used for data processing and analysis.

Results. Our findings confirmed that kidney cancer is characterized by a low death rate. Over the last 18 years, median survival of kidney cancer patients in the North-Western Federal District of Russia increased form 4 years to 6.5 years. The 1-year survival rate increased from 68 % to 78.5 % (by 16.5 %); 5-year cumulative observed survival increased from 47.3 % to 54.1 %; 5-year cumulative relative survival increased from 56.8 % to 61.8 %. Female kidney cancer patients demonstrated higher 5-year cumulative survival rates than male patients (65.8 % vs 43.9 %).

Conclusion. We observed a positive dynamic of the main analytical indicators of cancer control, including an increase in the median survival and 5-year cumulative survival of kidney cancer patients.
«Snail on the Slope» by the Strugatsky Brothers:
Authors: Izotov V.P.
Published: August 2022

The work is aimed at identifying linguistic features in the story of the Strugatsky brothers "Snail on the slope". Six etudes devoted to various linguistic realities are presented. In particular, the following points are considered: the pace of speech, linguistic interpretation of events, methods of deciphering the text, new words, substantiation of prepositions, features of the use of the conjunction but. The results obtained complement the general reflexive linguistic picture of the works of A.N. and B.N. Strugatsky.
Mental ecology in the structure of the COVID-19 pandemic (review)
Authors: Vasileva Anna V. , Neznanov Nikolay G. , Soloviev Andrey G.
Published: August 2022

Currently, sufficient data are available on the negative impact of the COVID-19 pandemic and its socio-economic consequences on human mental health and the mental ecology in general. The success of public health strategies to cope with pandemics is largely determined by psychological factors and the mental values prevailing in the community at large.
The present review systematized the psychological response features of various social, professional, and national representatives during the COVID-19 period within the framework of the main mental ecology provisions.
The review methodology was based on the World Health Organization documents and open sources of the Scopus and Web of Science databases on the population's mental health under COVID-19 pandemic conditions.
A significant increase in adaptive and anxiety-depressive disorders was noted during the COVID-19 pandemic. Among the specific mental phenomena associated with the pandemic, coronaphobia, COVID-19-stress syndrome, covid-dissidence manifestations with the involvement of conspiracy theories, and mythological thinking were identified. The negative infodemia impact on the mental ecology, as well as the adherence to anti-epidemic measures and readiness for vaccination, were also established. Negative trends were demonstrated in communities where the maximum infection and death risk were associated with low adherence to the epidemiological measures and refusal to vaccination.
It was revealed that belonging to certain social or professional groups largely determines a person's behavior in relation to a new coronavirus infection within the framework of accepted social norms. Based on the analysis of a large domestic and international data number on the impact of the COVID-19 pandemic emergency on the human psyche, its significant adverse contribution to the overall mental ecology was noted. The necessity of developing special therapeutic and psycho-prophylactic programs aimed at coping with the stress pandemic impact and treatment of affective disorders, countering infodemia, and strengthening behavioral patterns to maintain mental health and personal well-being is substantiated.
They don't always know what they're going to do, but they know how to do it
Authors:   , Lyons Sara , Yau Pamela
Published: August 2022

Immersive theatre is a growing creative industry in the United States today, both in its own right and in connection to the current trend of experiential marketing. Despite this, the current body of academic literature is sparse on research into the experiences and needs of immersive theatre administrators and managers, including best practices in safety and business model and business structure considerations for founders. This thesis explores the concerns central to running an immersive theatre company, including how managers handle and facilitate the development of artist-audience relationships in immersive theatre productions; what special considerations managers need to make for site-specific immersive work; how managers acquire immersive management knowledge; and what changes in praxis are on the horizon due to changes in the theatre landscape as a result of COVID-19. These questions are explored through multiple case studies on successful immersive theatre companies of varying sizes currently operating in the United States, chiefly through interviewing administrators, managers, and other personnel at each company to learn from their perspectives on their work. The data collected in this process leads us to discover that a framework of immersive management will require a reimagining of theatre managerial responsibilities as they are currently understood in order to accommodate the specialized circumstances in immersive productions. Furthermore, the research conducted herein suggests that there is much more ground to be broken in this field of study, and the author concludes with suggestions for further avenues of study based on interview data from active practitioners.
Empezando a transformar bases de datos con R y dplyr
Authors:   Universidad Icesi, Alonso Cifuentes Julio César
Published: August 2022

Si estás leyendo este libro, ya haces parte de la comunidad que emplea R para analizar datos. Esta obra tiene como objetivo presentar una primera aproximación al paquete dplyr que permite manipular rápidamente bases de datos en R. Si eres nuevo en el universo de R o en el uso del paquete dplyr, este libro puede ser un buen punto de arranque. Si ya eres usuario de dplyr, seguramente este libro no te aportará nuevos conocimientos, pero puede ser una herramienta de consulta de algunos conceptos básicos.
Protective effect of carwin capsules against cyclophosphamide induced chromosomal aberrations in mice
Authors: Thakur Niharika , Upmanyu Neeraj , Saxena Rajiv
Published: August 2022

The concept of polyherbalism has been highlighted in , an Ayurvedic literature dating back to 1300 AD. Polyherbal formulations enhance the therapeutic action and reduce the concentrations of single herbs, thereby reducing adverse events. In the present study, the clastogenic effect of carwin capsuleshas been evaluated against cyclophosphamide (CP)-induced chromosomal aberrations in the bone marrow cells of the mice. Genotoxicity was carried out in mouse bone marrow cells. Animals were divided into four groups each containing four animals. Group I (control) was treated orally with vehicle (acacia suspension- 1ml/100gm), Group II was treated i.p. with cyclophosphamide (50 mg/kg, bw.), Group III was treated orally with carwin alone (1.5 mg/animal, bsa.), and Group IV was treated with cyclophosphamide + carwin. Animals were pretreated for 7 days with test drug (carwin). The evaluating parameter was to count total number of aberrated chromosomes and its various types. The results demonstrate that carwin was found to be significant (P<0.01) as compared to cyclophosphamide treated as the no. of total aberrated chromosomes in carwin treated was decreased effectively. And also carwin was able to significantly (P<0.01) protect the action caused by cyclophosphamide as well was also found to be effective antigenotoxic (P<0.01) as compared to cyclophosphamide, when total no. of aberrated cells and their types were scored. Therefore, the results suggest a genotoxic potential of carwin capsules.
ЦИФРОВІ ТЕХНОЛОГІЇ У ПРОФЕСІЙНОМУ РОЗВИТКУ ПЕДАГОГІЧНИХ ПРАЦІВНИКІВ
Authors: Кондратова Людмила Григорівна
Published: August 2022

У статті розглядається роль цифрових технологій в професійному розвитку викладачів закладів вищої, фахової передвищої та загальної середньої освіти в системі інформальної освіти, подаються приклади самоосвітньої діяльності педагогічних працівників з розвитку цифрової компетентності, аналізуються освітні досягнення, що здобуваються в процесі навчання за дистанційними авторськими курсами в умовах відкритого університету післядипломної освіти.
Bacteriological characteristics of hypervirulent Klebsiella pneumoniae rmpA gene (hvKp-rmpA)-harboring strains in the south of Iran
Authors: Shoja Saeed , Ansari Maryam , Bengar Saman , Rafiei Azam , Shamseddin Jebreil , Alizade Hesam
Published: August 2022

Background and Objectives: To provide data on the occurrence of classical K. pneumoniae (cKp) and hypervirulent Klebsi- ella pneumoniae (hvKp) strains harboring the gene encoding regulator of mucoid phenotype A (rmpA) and evaluated charac- teristics of virulence biomarkers, carbapenemase, extended-spectrum-β-lactamase (ESBL)-producing, and capsule serotypes among K. pneumoniae clinical isolates collected in the south of Iran.
Materials and Methods: A total of 400 K. pneumoniae isolates were collected. First, the K. pneumoniae isolates were screened for rmpA gene by PCR, and then they were characterized for the presence of the virulence genes (pagO, iucA, iroB, luxR), capsular serotype genes (K1, K2, K5, K20, K54, and K57), carbapenemase (bla , bla IMP, bla , bla KPC , bla ,bla OXA-48 , and bla ) and ESBL (bla CTX-M SHV and blaTEM) genes. For all K. pneumoniae isolates phenotypic tests in- clude of string test and disk diffusion test were performed.
Results: In total, 16 (4%) hvKp-rmpA+ and 384 (96%) cKp were observed. Of hvKp-rmpA+ strains, 16 (100%) were carried pagO, iroB, and luxR genes, and 13 (81.3%) strains harbored iucA gene. The most prevalent capsular type genes were K1 (62%) and K2 (19%) in hvKp-rmpA+ strains. The incidence of bla SHV gene in hvKp and cKp was 94% (15/16) and 87.5% (336/384), respectively. The cKp isolates carried bla. NDM (30/384; 7.8%) gene.
 
Conclusion: Our data suggest that the incidence of hvKp was low. Also, hvKp-rmpA+ strains have less antibiotic resistance than cKp isolates. Serotypes K1 and K2, and bla SHV gene were strongly associated with hvKp-rmpA+.
Identification, characterization and antibiotic susceptibility testing for Bacillus species
Authors: Eldin Fahim Noha Alaa , El-Wahed Ismail Ghada Abd , AbdelAleem Moataz Bellah , Elanany Mervat , Saber Sally Mohamed , EL-Ashry Marwa Abd EL-Rasoul
Published: August 2022

Background and Objectives: With the increase in immunosuppressed patients and antimicrobial misuse, Bacillus species have risen as opportunistic pathogens in hospitalized patients. The present study aimed at comparing chromogenic media, automated identification cards versus MALDI-TOF as the gold standard method for identification of different Bacillus spe- cies and determining minimal inhibitory concentration (MIC) of different antibiotics by broth microdilution method (BMD) to suggest recommendations for Bacillus treatment.
Materials and Methods: The study included 30 Bacillus species isolates recovered from normally sterile sites of the human body and were subjected to identification by MALDI-TOF, Vitek-2c, and HiCrome Bacillus Agar. BMD test was performed to determine the MIC of vancomycin, gentamicin, and ciprofloxacin.
Results: Our study showed B. cereus was the most commonly isolated species (76.66%) followed by B. subtilis (23.33%). Regarding the different methods of identification, the highest agreement with MALDI-TOF was exhibited by HiCrome agar without polymyxin B (93.3%) followed by Vitek-2C and HiCrome agar with polymyxin with an agreement of 83.3%. Concerning the antibiogram, the tested isolates showed a susceptibility of 93.3%, 86.6%, and 83.3% towards vancomycin, gentamicin, and ciprofloxacin respectively.
Conclusion: In conclusion, we spotlight that Bacillus species should no longer be considered contaminant bacteria in cul- tures, particularly in immunosuppressed patients. HiCrome Bacillus Agar without polymyxin B displayed the highest agree- ment with MALDI-TOF. Hence, it represents a good option for identification for routine laboratories where expensive instru- ments are unavailable. The high susceptibility towards the tested antibiotics can suggest the possibility of empirical use of vancomycin, gentamicin, and ciprofloxacin.
Expression analysis of miRNA-155 level in Helicobacter pylori related inflammation and chronic gastritis
Authors: Mahboobi Ramina , Fallah Fatemeh , Yadegar Abbas , Dara Naghi , Kazemi Aghdam Maryam , Asgari Behnoush , Hakemi-Vala Mojdeh
Published: August 2022

Background and Objectives: Helicobacter pylori, is a major etiologic agent associated with gastritis. There is more evi- dence of noncoding microRNAs (miRs) dysregulation in gastrointestinal diseases, including inflammation caused by Helico- bacter pylori. Also, the classification of gastrointestinal malignancies using the miRs profile is better than the protein profile. MiRNA-155(miRNA-155) among other miRs plays an important role in control of inflammation and gastric malignancy, so it can be remarkable prognosis marker of gastric cancer in the phase of chronic gastritis. The aim of this study was to compare the expression of miRNA-155 in gastric biopsy and serum samples of adult patients with chronic gastritis.
Materials and Methods: Biopsy and blood samples were collected from endoscopy candidates at Taleghani hospital, Tehran, during 2019. H. pylori infection was detected using histology, culture and molecular PCR methods. Based on cagA and vacA genotyping, the toxicity of H. pylori isolates were determined. After RNA extraction, the expression rate of miRNA-155 was evaluated by real-time polymerase chain reaction (RT-PCR) in gastric tissue and serum of adults infected by H. pylori (n = 30) compared with control group without infection (n = 20). RNU6 housekeeping miRNA were used as endogenous control and statistical analyses were performed using SPSS, ANOVA and Student’s t-test.
Results: miRNA-155 expression in H. pylori infected adult patients increased significantly by 5.61 and 10.11 fold in serum and tissue respectively, compared to that observed in the control group. Evaluation of miRNA-155 expression pattern in relation to bacterial virulence factors showed that the increase in miRNA-155 expression is independent of CagA and VacA toxins.
Conclusion: According to the differential expression patterns of miRNA-155 in serum samples of the infected adult patients, miRNA-155 has the potential to evaluate as chronic gastritis marker.
Prevalence and genotypic characterization of human parvovirus B19 in hemophilia patients
Authors: Keshavarz Mohsen , Janati-Namin Nahid , Arjeini Yaser , Mokhtari-Azad Talat , Rezaei Farhad
Published: August 2022

Background and Objectives: Parvovirus B19 (B19V) is usually transmitted through respiratory tract, but can also be received through blood transfusion. This study evaluated the seroprevalence, DNA existence, and circulating genotypes of B19V in hemophilia patients.
Materials and Methods: Serum samples of cases and controls were analyzed for B19V using ELISA and real-time PCR. Finally, obtained sequences were used for genotyping.
Results: Among cases, 3% were anti-B19V IgM positive and 47% were anti-B19V IgG positive and B19V DNA was detect- ed in 16% of them. However, among controls, 38% were anti-B19V IgG positive (P>0.05) and 5% were B19V DNA positive (P= 0.019). Also ~13% of cases were positive and all of controls were negative for IgG avidity test (P= 0.029). Viral load in case group was higher than control group (P = 0.037).
Conclusion: Since hemophilia patients receive large amounts of blood factors, prevalence of B19V in these patients might be higher than normal subjects.
O Programa Horizonte 2020 da União Europeia e a perspectiva universidade de classe mundial: aproximações e tendências
Authors: Thiengo Lara Carlette , Bianchetti Lucídio
Published: August 2022

Neste artigo analisamos o Programa-Quadro da União Europeia (UE) para a Investigação e a Inovação – Horizonte 2020, lançado pela Comissão Europeia em 2014, como parte da Estratégia Europa 2020. O objetivo é demonstrar como este Programa é estruturado/fundamentado a partir de elementos da concepção de World Class University, (Universidade de Classe Mundial) que vem sendo difundida pelos Organismos Internacionais, especialmente o Banco Mundial, Think-Thanks, especialistas e rankings acadêmicos. Para isso, em termos teóricos-metodológicos, utilizamos o levantamento bibliográfico e a análise documental, buscando compreender as totalidades das relações/fenômenos, bem como as contradições, influências, relações de força e projetos em disputa que os atravessam. Por ora, compreendemos que H2020 “coroa” o longo processo de relativização de determinada universidade europeia, instaurando/reforçando uma concepção de universidade que vai ao encontro de características do modelo de excelência ou de classe mundial.
Experiência museal no distrito de Mazagão Velho-AP: visitação em movimento
Authors: Videira Piedade Lino , Vasconcelos José Gerardo
Published: August 2022

Neste artigo, deu-se enfoque ao território distrital de Mazagão Velho, localizado no município de Mazagão, estado do Amapá, como espaço museal afro-amapaense, ante a sua relevância histórica e cultural, como reduto de negras e negros que protegem do apagamento e esquecimento suas heranças culturais/religiosas, as quais resistem ao tempo e conformam a geografia social da comunidade. A metodologia utilizada pautou-se em estudo teórico-bibliográfico e com base em entrevistas semiestruturadas, endereçado a oito guardiões culturais, sendo quatro mulheres e quatro homens atuantes na comunidade. Concluiu-se que a cultura, a memória e a territorialidade, numa perspectiva educativa e patrimonial, sinalizam ser uma ação comunitária e recurso didático-pedagógico estratégico para salvaguardar  patrimônio cultural na/da comunidade.
Experiencias docentes, casos relevantes en la práctica docente y formación de profesores
Authors: Cortez Sic José Enrique , Rivas Oscar Hugo López , Crispin Haydee Lucrecia
Published: August 2022

Resumen: El trabajo trae reflexión sobre prácticas pedagógicas relevantes, asumidas como “casos de enseñanza”, y que fueron identificadas, valoradas y analizadas por un gran número de docentes en servicio en la red educativa. Estos docentes han sido seguidos y, a partir de la identificación de innovaciones en sus tareas en el aula, actúan como sujetos de sistematización de estas experiencias. Esto asegura un registro histórico al servicio de las nuevas generaciones de docentes que, al consultar estos documentos, encontrarán experiencias enriquecedoras para la mejora del sistema educativo. Antes de presentar estas relevantes experiencias, se presenta a modo de introducción un breve panorama de la formación inicial y continua de los docentes en Guatemala, en particular la implementación de una estrategia consensuada entre los profesores guatemaltecos y la Universidad Nacional de Guatemala a través de la Escuela de Educación. Formación de Docentes de Educación Primaria, quienes actuaron como mediadores ante el Ministerio de Educación, alcanzando acuerdos impensables que facilitaron la implementación de medidas para mejorar la formación docente y también acciones que constituyeron reformas básicas para la educación en el país. En educación se valoran los resultados a medio y largo plazo, y estas transformaciones se vienen implementando desde hace más de una década. En este análisis, la evidencia que surge de este proceso se destaca de la experiencia de los docentes cuya formación se desarrolló en el ámbito del Programa Académico de Desarrollo Profesional Docente.

Palabras claves: Formación docente. Prácticas relevantes en el aula. Casos de enseñanza. Escuelas normales. Reformas básicas.
Resenha Pedagogia histórico-crítica, quadragésimo ano: novas aproximações
Authors: PADILHA ANNA MARIA LUNARDI
Published: August 2022

A Pedagogia Histórico-Crítica, enquanto construção coletiva de uma teoria pedagógica revolucionária, acumula experiências de quatro décadas de estudos e práticas em favor de uma educação de qualidade para todos. Este livro - Pedagogia Histórico-Crítica, quadragésimo ano: novas aproximações – é a reunião das conferências realizadas pelo autor – Dermeval Saviani – entre dezembro de 2006 e março de 2019. A obra em questão dá continuidade ao Pedagogia Histórico-Crítica: primeiras aproximações, publicado pela primeira vez em 1991.
Cerebral hyperperfusion syndrome after endovascular stent graft reconstruction for postirradiated carotid blowout syndrome: a case report
Authors: Huang Yu-Cheng , Lin Yen-Heng , Lee Chung-Wei , Liao Ting-Wei
Published: August 2022

Background: Cerebral hyperperfusion syndrome (CHS) is a failure of autoregulation after a revascularization procedure. It has rarely been reported in patients with no pre-existing cerebral hypoperfusion. Case Report: We present a rare case of a patient who underwent stent graft implantation to treat postirradiated carotid blowout syndrome. The patient developed hypertension, focal neurological deficit, and seizures after the procedure; neuroimages revealed ipsilateral cerebral edema, swelling, and increased cerebral perfusion. CHS was diagnosed based on clinical and radiological findings. The patient recovered gradually after receiving supportive care. Conclusion: Owing to the risk of CHS, monitoring for cerebral perfusion and prevention of hypertension is suggested for patients who undergo stent graft placement for postirradiated carotid blowout syndrome.