bluuebunny/crossref_metadata_2025 huggingface dataset:
Photothermal Quotient-An Effective Thermal Index for Evaluation of Lentil (Lens culinaris L.) Phenology and Yield in the Lower Gangetic Plains
Authors: Maji S. , Chakraborty P.K. , Nath R. , Mondal S. , Dey S. , Bandopadhyay P. , Banerjee S.
Published: October 2022

Background: Sowing time and variety-specific genetics influence the phenological development of lentil (Lens culinaris L.), affecting its heat and solar energy utilization for attaining satisfactory yield. The present study was conducted to assess how the different thermal indices behaved in explaining variation in phenology and yield components with corresponding effects on yield of lentil varieties grown under varying sowing dates. Methods: The experiment comprised of four sowing dates in the main plots and five lentil varieties in the sub-plots, laid out in a split-plot design replicated thrice. The phenology, yield components and yield were recorded. The computed thermal indices and correlation and regression analyses were used to assess their effects on yield traits and yield. Result: Sowing after 7th November reduced lentil yield by 13.6-22.5 kg ha-1 day-1 and 0.9-2.1% ha-1 day-1 on absolute and relative basis, respectively. The varieties WBL 77 and HUL 57 were less sensitive to temperature fluctuations resulting in stable yield performance under varying thermal regimes. Despite significant influence of temperature on yield traits, growing degree days explained 82.0-89.0%, while photothermal quotient (PTQ) explained 92.0-96.0% of the total variation in yield. PTQ emerged as a reliable yield predicting thermal index and might be used for breeding climate-smart lentil varieties.
Alleviation of Salt Stress with Chitosan Foliar Application and Its Effects on Growth and Development in Tomato (Solanum lycopersicum L.)
Authors: ÖZKURT Nazlı , BEKTAŞ Yasemin
Published: October 2022

Environmental and climatic fluctuations as well as abiotic stress factors affect agricultural production and cause a loss in quality and yield. It is important to find alternative solutions for the sustainability of agricultural production to feed the increasing population. Salt stress is one of the most devastating abiotic stress factors and tomato (Solanum lycopersicum L.) production is also affected by salt stress since it needs extensive irrigation for high yield. The exogenous application of some plant inducers showed promising results in the induction and improvement of plant tolerance to stress factors. Chitosan (2-amino-2-deoxy-b-D-glucosamine), one of the organic compounds, is getting significant attention in agriculture with its potential. Here, we evaluated the potential of chitosan application for salt stress tolerance on tomato. 0.03% and 0.05% chitosan solutions were applied as a foliar spray to the plant and salt tolerance improvement were investigated under untreated (0 mM NaCl) and 100 mM NaCl conditions. The growth-related (root and shoot diameters, above and below-ground biomass, number of leaves and branches, and plant height), photosynthetic parameters (chlorophyll a, b, total carotenoid content), and ion leakage were investigated. According to the results, chitosan application improves plant development in both untreated and salt-stress conditions and improved plant growth. Also, photosynthetic parameters showed that the application of chitosan increased chlorophyll contents under untreated conditions. Our result suggests that the application of chitosan may have a promising effect on salt stress tolerance and further research may shed light on its molecular mechanisms.
Anterior Biopercular Syndrome Caused by Unilateral Infarction
Authors: Brandão Eva , Ferreria Augusto , Leal Loureiro José
Published: October 2022

The anterior biopercular syndrome is characterized by facio-pharyngo-glosso-masticatory diplegia, with automatic dissociation of movements. It generally translates bilateral opercular lesion, often of vascular etiology. There are very few cases described with unilateral lesions. We present the case of a patient with a bilateral anterior opercular syndrome caused by unilateral infarction.
Estudos Observacionais na Era da Medicina Baseada na Evidência: Breve Revisão Sobre a Sua Relevância, Taxonomia e Desenhos
Authors: Fronteira Ines
Published: October 2022

Nesta revisão narrativa da literatura, distinguimos entre estudos experimentais e estudos observacionais, realçando a importância que estes últimos têm vindo a ganhar na era da medicina baseada na evidência cujo gold standard são os estudos experimentais. Apresentamos uma taxonomia para os estudos observacionais que se baseia nas unidades de observação e na medição (transversal ou longitudinal). Distinguimos entre estudos descritivos e estudos analíticos. Em seguida, e dada a sua especificidade, definimos e apresentamos uma classificação própria para os estudos ecológicos. Definimos e tecemos considerações sobre as vantagens e desvantagens dos estudos transversais, de caso controlo e de coorte. Analisamos a força da evidência de cada desenho de estudo. Terminamos concluindo sobre o que deve orientar a escolha do desenho de estudo.
Suicídio nos Mais Velhos: Fundamental Não Esquecer!
Authors: Sampaio Daniel , Telles-Correia Diogo
Published: October 2022

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Dermatose Marítima por Contato com uma Caravela-Portuguesa
Authors: Moleiro Susana , Pereira Andreia , Paiva Lopes Maria João
Published: October 2022

Durante a época do Verão, as lesões cutâneas que surgem na praia são um motivo frequente de recurso aos serviços de urgência e de consulta de dermatologia. Os autores descrevem o caso de uma criança com uma lesão maculopapular dolorosa que resultou de um provável contato com uma caravela-portuguesa. Não apresentava outros sinais ou sintomas pelo que foi medicada em ambulatório com analgesia, anti-histamínico e corticoide tópico. Após uma semana de evolução constatou-se resolução completa das lesões cutâneas. Apesar da gravidade da maioria dos casos de dermatoses marítimas encontradas em Portugal ser ligeira, considera-se ser importante o estudo da fauna e da flora de cada região para adequar os cuidados terapêuticos.
A ressonância magnética na doença de crohn do intestino delgado
Authors: Ramalho Miguel , Herédia Vasco , Cardoso Cláudia , Matos António P , Palas João , De Freitas João , Semelka Richard C
Published: October 2022

A doença de Crohn (DC) é uma doença inflamatória intestinal de carácter crónico e recidivante, que atinge em muitos casos doentes jovens. Os métodos de imagem são indispensáveis no seu diagnóstico, na monitorização da progressão da doença e na resposta ao tratamento. Na prática clínica actual, a avaliação imagiológica da DC é efectuada de forma crescente por técnicas de imagem seccional, em particular a tomografia computorizada e a ressonância magnética (RM), permitindo a visualização simultânea do lumen e da parede intestinal, bem como a extensão extra-entérica. A enterografia por RM permite uma avaliação segura e não-invasiva destes doentes, sem necessidade de exposição a radiação ionizante. O novo paradigma de imagem deve contemplar a segurança do doente como um aspecto essencial na escolha do método de imagem. Por esta razão, a ressonância magnética poderá ser o método de avaliação preferido para a avaliação do intestino delgado, especialmente em doentes jovens com DC, considerando que a maioria irá realizar estudos de repetição. Além disso, a informação sobre a actividade da doença não é equiparável por qualquer outro método de imagem. Neste artigo de revisão os autores discutem os aspectos essenciais da utilização da RM na DC, incluindo o protocolo e os principais achados de imagem, fazendo ainda referência às suas vantagens comparativamente a outros métodos, nomeadamente no que diz respeito à segurança, à acuidade diagnóstica e à potencial importância na abordagem terapêutica desta doença.
Estudos Genéticos em Doentes Portugueses com Esclerose Múltipla
Authors: Bettencourt Andreia , Martins da Silva Ana , Pinho e Costa Paulo , Martins Silva Berta
Published: October 2022

A esclerose múltipla (EM) é uma doença crónica, neuroinflamatória e auto-imune que resulta de uma interacção complexa entre factores genéticos e ambientais. Como em outras doenças complexas, com características auto-imunes, a associação genética com o complexo major de histocompatibilidade (HLA no Homem) está bem documentada. Nos últimos anos vários estudos de associação genéticos têm sido realizados em doentes portugueses com esclerose múltipla. Genes como o HLA-DRB1, HLA-A, HFE, TNFA, CTLA-4, PTPN22 e a Apolipoproteina E (ApoE) foram investigados. A ApoE, os alelos 1858T do gene do PTPN22, -318C do gene CTLA-4, -308A do gene TNFA, -1237C do gene TLR9 e os polimorfismos do gene HFE parecem não estar associados ao desenvolvimento de EM. O alelo HLA-DRB1*15 foi confirmado como o principal marcador genético de susceptibilidade à doença. Foi também observado que a presença dos alelos HLA-A*02 e TNFA-238A diminui o risco de desenvolver esclerose múltipla, e que a presença da variante C282Y do gene HFE parece conferir um pior prognóstico. Por outro lado, o alelo HLA-DRB1*15 e o alelo 1858T do PTPN22 estão associados, na nossa população, a um curso benigno da doença.
Ciência em cordel
Authors: Klautau Fabiana Dias , Jansen Marina Beatriz Haddad
Published: October 2022

O objetivo desse artigo é apresentar a elaboração de um Cordel in fólio sobre o tema Biomas do Brasil, com capa produzida por meio da técnica de xilogravura, trabalhada com alunas do 7º ano do Ensino Fundamental em uma escola sediada na cidade de São Paulo, SP, em sequência didática realizada pelas professoras de Ciências e Língua Portuguesa. Em uma abordagem à luz da História da Ciência, foi apresentada a xilogravura como técnica para ilustrações de obras sobre animais e plantas na primeira modernidade. Posteriormente, trabalhou-se o emprego da técnica na elaboração da literatura de cordel, o surgimento do cordel no Brasil e o início da produção de folhetos na região Nordeste, em meados do Século XIX, cuja perpetuação foi atribuída ao uso da técnica da xilogravura. Como conclusão da atividade, as alunas produziram Cordéis criando poemas com o tema proposto, respeitando métrica e rima, organizados em fólios. A técnica da xilogravura foi empregada na produção da capa para o poema.
A mineração e os limites geográficos na colonização de Cuiabá e Mato Grosso
Authors: Garcia Pedro Maciel de Paula , Bonfim Carolina Santos
Published: October 2022

O presente trabalho objetiva explorar as relações entre a mineração e a construção do território mato-grossense, ao longo de mais de 300 anos de colonização. Para tal, foram congregadas informações obtidas em fontes primárias dos séculos XVIII (correspondências oficiais) e XIX (notícias de jornal), em trabalhos de campo e levantamento bibliográfico. O eixo de análise central se baseia em momentos históricos que remetem à ocupação de regiões com relevantes recursos minerais ou episódios de migração motivados pela descoberta de ouro ou diamante. Em Mato Grosso, os primeiros núcleos de ocupação foram iniciados e mantidos por causa da mineração e garantiram a expansão do território brasileiro a oeste, em uma dinâmica de “corridas” por ouro e diamantes, que ainda se repete atualmente.
Determinants of Postpartum Blues in Indonesia
Authors: Kurniawati Dini , Septiyono Eka Afdi
Published: October 2022

Introduction: The condition of postpartum blues is difficult to detect as it is still considered an instinct from a mother. Postpartum blues is a psychiatric disorder that, if left untreated, causes severe mental problems. This study aims to determine the factors that influences postpartum blues in postpartum mothers.Methods: This study used a cross-sectional method. The population in this study were mothers who gave birth at Balung Hospital. The sample obtained were 330 mothers who gave birth from January to December 2019. The instrument used was a questionnaire consisting of the Edinburgh Postnatal Depression Scale, a family support questionnaire, and a questionnaire to determine the respondent's characteristic data (age, salary, education, employment, type of labor, husband support, pregnancy status, and risk of postpartum blues)Results: The results of the analysis using the chi-square found that the determinants of postpartum blues are age (p=0.002), salary (p=0.032), education (p=0.001), occupation (p=0.042), type of delivery (p=0.0001), husband's support (p=0.003), and pregnancy status (p=0.009) with p <0.05.Conclusion: Mothers who receive the related factors will feel that they are valuable and needed and therefore a sense of happiness and comfort will arise to improve the mother's mood. Health workers can support the factors that promote the reduction of the postpartum blues status.
Understanding the Barriers Againts Eco-Friendly Behavior
Authors: Restya Winda Putri Diah
Published: October 2022

Over the past two decades, increased media coverage – coupled with economic incentives has substantially raised citizens’ awareness and concern about environmental sustainability, but has typically failed to induce persistent behavioral changes. The ineffectiveness may due to the fact that all this time the discussions and efforts to tackle environmental problems, research conducted, and policies made by the government are always based on non – psychological perspective, such as legal studies, economic, and policy maker perspective. Effort from psychological perspective is relatively not easy to find whereas acting sustainably itself is actually a form of behavior. Hence, this study attempt to understand the gap between awareness of environmental sustainability and individual’s actual behavior from a psychological perspective. The primary objective is to identify the barriers for individuals in implementing eco-friendly behavior. The data was obtained by using descriptive research method through semi-structured interview, non-participant observation combined with social experiment. As many as 32 respondents participated and chosen through incidental sampling technique. The research started by showing seven images that reflected environmental issues in order to do the mapping on participants’ stage of knowledge. the results showed that there is clear evidence on “awareness -behavior” gap while barriers to act environmentally such as: laziness, underestimate their behavior toward the environment, feeling powerless to do some changes, absence of reward and punishment.
Development and research of refrigeration cycle with biagent jet compressor
Authors: Trokoz Ya.Ye. , Barabash P.O. , Kudelya P.P. , Golubev O.B.
Published: October 2022

Background. Currently, in the cycles of steam-ejector refrigeration machines (SERM) are used monoagent jet compressors, the working body in which is water. Despite their low efficiency, SERM have a number of advantages over refrigeration machines that usemechanical compressors: low cost, ease of manufacture and reliability. The use of SERM is largely limited by the inability of these installations to reach temperatures below 0 °C. This limitation can be overcome by applying a fundamentally new steam compressioncycle using a bioagent (water-freon) jet compressor (BAJC).Objective. The purpose of the paper is experimentally confirm the operability of a refrigeration machine operating on a steam compression cycle using a bioagent (water-freon) jet compressor. Determine the efficiency of the experimental refrigeration machine andfind the optimal geometric characteristics of the jet compressor.Methods. An experimental stand was created to study the refrigeration plant using BAJC. The refrigeration machine efficiency e was determined according to the developed method.Results. Experimental values of the cooling machine coefficient e were obtained depending on the change in the ejection coefficient q of BAJC. The maximum machine coefficient values emax = 1,3 ÷ 1, 4 correspond to those of the ejection coefficient q opt ≈опт 0, 25q 0,25, which also achieves the maximum efficiency h ≈max 0,35 ÷ 0, 45 of the BAJC.Conclusions. The efficiency of a refrigeration unit operating on a steam compression cycle using a bioagent (water-freon) jet compressor has been experimentally confirmed. To expand the temperature spectrum of the cycle in the direction of lowering the boilingpoints in the evaporator (tboilt −≤кип 20 °C), it is planned to modernise the laboratory bench by using aqueous salt solutions as a coolant.
Controlling the thickness of the plastic layer applied using 3D printing by electromagnetic acoustic method
Authors: Druziev Maksym S. , Podolian Oleksandr O. , Tymchik Grigoriy S.
Published: October 2022

Background: Currently, the EMA method is not used to control the thickness of the layer of plastic applied to a metal platform using 3D printing, which significantly limits the scope of its use. However, EMA flaw detectors are widely usedto control the quality of the metal platform itself. The solution of the problem of radiation research will allow carrying out complex control of the thickness of the layer of plastic applied by 3D printing, which will increase the efficiency ofultrasonic flaw detection in the reliability and speed of work.Objective: This article considers the possibility of determining the thickness of the layer applied by 3D printing using electromagnetic-acoustic (EMA) method.Methods: The analysis of the relationship between the thicknesses of the layer of plastic applied by 3D printing on theacoustic pressure created in it during the control using EMA transducers. The influence of the thickness of the plastic layer applied to the metal platform by means of 3D printing on the acoustic parameters of the EMA transducer was investigated with the help of mathematical modeling. Experimentally obtained dependences showing the influence of the thickness of the layer applied by 3D printing on the generated acoustic pressure.Results. The effect of the thickness of the plastic layer applied to a metal platform using 3D printing on the acoustic parameters of the EMA transducer is studied using mathematical modelling.Dependences showing the effect of the thickness of the plastic layer applied to the metal platform using 3D printing on the created acoustic pressure are obtained experimentally. The maximum acoustic pressure is created when there is no thickness of the plastic layer applied to the metal platform using 3D printing. The pressure drops sharply, as the layerthickness increases.Conclusions: Good convergence of the outcome of theoretical and experimental studies is demonstrated, with the approximation error of experimentally obtained data generally not exceeding 5%.The study is based on a widely proven approach to analyzing the process of acoustic wave formation by an EMA transducer. The reliability of the results obtained is confirmed by the correct use of the mathematical tools and goodconvergence of the outcome of theoretical and experimental studies.
52 ve 53 Numaralı Şer’iye Sicili Defterlerine Göre Amasya Sancağı’nda İçtimai Yapı
Authors: KARADENİZ Yılmaz
Published: October 2022

Amasya Sancağı, on sekizinci asrın ikinci yarısına gelindiğinde artık şehzadeler tarafından idare edilmemiş, idareci olarak mutasarrıflar tayin edilmişse de bunlar da çoğu kez görev yerlerine gitmemiş, yerlerine mütesellim göndermişlerdir. İdari olarak görülen yetersizlikler halka yansımış, geçici olarak alınan, ancak daha sonra sürekli hale gelen vergiler, taşradaki halkı huzursuz etmiştir. Bundan istifade eden eşkıya taifesi, yanlarına adam bulmada zorlanmamıştır.
Amasya Sancağı’nda önce geçici, daha sonra sürekli toplanan avarız ve nüzûl vergileri için belirlenen haneler üzerinden sancağın nüfusu yaklaşık olarak tespit edilmeye çalışılacaktır. Ayrıca sicillerde sıkça geçen Müslim ve gayr-ı Müslim insanların esnaf ve ticaretteki ortaklıkları, içtimai hayatları ve sosyal ilişkileri üzerinde durulacaktır. Farklı dinlere mensup insanların Müslümanlar ile aynı mahallelerde yaşamaları ve dinden dolayı hiç kimsenin kendisini farklı tutmadığı ve karşılıklı hoşgörü içerisinde bütünleştikleri görülecektir. Bu yüzden Amasya Sancağı’nda sosyal tabakalaşmanın olmadığı, şehzadeler tarafından çok sayıda medresenin açılması ve şehrin bir ilim merkezi olması sebebiyle alimler şehri olarak anıldığı, bu kesimin de halk ile iç içe yaşayarak kendilerini ayrı tutmadıkları üzerinde durulacaktır. Sicillere yansıdığı kadarıyla halk arasında bazı ailelerin meslek, görev, fiziki özellik ve alışkanlıklarına göre aldıkları lakaplar verilmeye çalışılacaktır.
A Rare Case of Asymptomatic Bilateral Naso-Orbital Meningoencephalocele
Authors: Litovets I. I. , Litovets T. S.
Published: October 2022

Meningoencephalocele is a rare pathology. By origin, it can be congenital and acquired. As a rule, congenital menigoencephaloceles are combined with various congenital skull structure anomalies, and are rarely asymptomatic. This pathology is most often solitary, and cases of multiple meningoencephalocele in one patient are extremely rare. The presented clinical case demonstrates an accidental finding: an unusual variant of symmetrically located bilateral naso-orbital meningoencephalocele with asymptomatic course in a 17-year-old patient.
Results of Two-Years Mammographic Screening in the Kaluga Region
Authors: Drzhevetskaya K. S. , Korzhenkova G. P.
Published: October 2022

Objective: approbation of the project of mass breast cancer mammographic screening in the Kaluga Region.Material and methods. From April 2018 to December 2019, screening mammography was performed in 35,439 women aged from 38 to 93 years (mean age 57.33 ± 8.07 years). The study was carried out on mobile mammography complexes assembled on Russian KamAZ vehicles with Russian-made equipment from Amiko company. Mammography was performed in frontal and oblique projections. BI-RADS ACR international classification was used to standardize the identified changes and assess the sensitivity and specificity of the study method.Results. Out of the total number of women examined, pathological changes (BI-RADS IV–V) were assumed according to mammography data in 778 (2.2%) cases, of which 700 (1.98%) patients appealed to an oncological institution. Benign processes were found in 394 (1.11%) patients, breast cancer in 164 (0.46%). Without verification of the diagnosis, 137 (0.39%) patients remained under the supervision of oncologists. Distribution of detected tumors by stages for 2 years of observation: stage 0 – 7, stage 1 – 73, stage 2 – 56, stage 3 – 13, stage 4 – 3. The stage was not set in 4 cases. The total number of those examined with verification of the diagnosis in the oncological institution was 596. The proportion of correct diagnoses was 94%. The total number of diagnostic errors that would occur in the absence of a true double scan accounted for 36 (6%) cases.Conclusion. The proposed screening method makes it possible to increase the breast cancer detection in the early preclinical stages of the disease, to provide the available diagnostics for the population due to mobile mammography complexes, and to speed up the process of diagnostics and further hospitalization for examination and necessary treatment according to the disease stage in a specialized oncological institution.
Method of Analysis of the Temporomandibular Joint Parameters According to Magnetic Resonance Imaging
Authors: Yudin D. К. , Gette S. А.
Published: October 2022

Background. The existing variety of approaches to the treatment of temporomandibular joint (TMJ) dysfunction corresponds to the variety of methods for its diagnosing. The absence of a universal technique of updating a particular diagnostic method data makes it impossible to evaluate the effectiveness of treatment.Objective: to evaluate the universality of magnetic resonance imaging (MRI) in the diagnosis and determination of tactics for the treatment of TMJ pathologies.Material and methods. One hundred patients of different age groups and genders with and without TMJ pathology were divided into groups according to Angle’s classification: Class 1 – 27 persons, Class 2 – 41, Class 3 – 32. The studies were carried out using Green 18 computer tomograph (Vatech, South Korea), Optima MR450W magnetic resonance tomograph (General Electric, USA), Dentograph digital Roshchin axiograph (Prosystom, Russia), SAM 2PX articulator (SAM Praezisionstechnik GmbH, Germany). The RadiAnt Viewer software was used.Results. We conducted a comparative analysis of the indicators of articular structures mutual disposition obtained using various methods of TMJ diagnosis. A technique for estimating TMJ parameters using the analysis of MRI data was proposed. A correlation was revealed between the indications obtained using various diagnostic methods.Conclusion. The developed method of TMJ structures analysis has high accuracy and is applicable in practice.
PRODUÇÃO DE TRANSGÊNICOS E O AGRONEGÓCIO NO POLO JUAZEIRO/PETROLINA
Authors: Sousa Raimunda Àurea Dias de , Teles Maria Genaria de Amorim
Published: October 2022

O agronegócio encontra-se, na atualidade, associado ao desenvolvimento e à alta tecnologia, especialmente, no que se refere à produção de sementes transgênicas (Organismos Geneticamente Modificados) como expressão da competitividade, rentabilidade, garantia de alimentos e progresso da ciência. Com base nisso, o presente trabalho tem como objetivo compreender como as terras são apropriadas pelo agronegócio, especialmente, para produção de milho transgênico cujo intuito é valor de troca – mercadoria; contraditoriamente, provoca a expropriação dos camponeses do bem natural (terra) e de um cultivo agroecológico que contém valor de uso. Para alcançar o objetivo, a metodologia utilizou-se de três eixos de operacionalização: a organização de uma pesquisa bibliográfica sobre a temática, visita à empresa Monsanto e comunidades rurais produtoras de sementes de milho e a coleta de dados estatísticos, que viabilizou a produção de gráficos, tabelas e mapas para melhor compreensão da expansão das sementes transgênicas e da resistência dos trabalhadores que vivem das sementes crioulas.
The Effect of Giving Avocado Leaf Boiled Water on Lowering Blood Pressure in the Elderly with Hypertension in the Work Area Gambut Health Center
Authors: Mar'iyah Khusnul , Rohman Aman , Fajar Ismul , Negara Chandra
Published: October 2022

Background: Hypertension is a condition of a person's blood pressure being at a level above normal, hypertension treatment can be done herbally using avocado leaves. Avocado leaves can lower blood pressure because they contain active substances, namely flavonoids and quercetin. This research was conducted in the working area of the Tilango Health Center. Objective: This study aims to determine the effect of giving boiled water of avocado leaves on reducing blood pressure in the elderly with hypertension. Methods: Design This study used a two-group quasi-experimental pre-test - post-test design. The sample is the elderly who have hypertension, amounting to 125 people with purposive sampling technique. The research instrument used a questionnaire. Results: Statistical test using T-Test on blood pressure before and after the intervention was given a significance value of 0.000 (p-value < 0.05 ). Conclusion : This study concludes that there is a significant effect between giving avocado leaf boiled water on reducing blood pressure in the elderly with hypertension in the working area of the Tilango Health Center.
LBM on non-uniform grids without interpolation
Authors: Berezin Arseniy Vladimirovich , Ivanov Anton Valerievich , Perepelkina Anastasia Yurievna
Published: October 2022

Lattice Boltzmann method (LBM) is a numerical scheme for solving fluid dynamics problems. One of the important and actively developing areas of LBM is the correct construction of the scheme on non-uniform spatial grids. With non-uniform grids the total number of calculations can be significantly reduced. However, at the moment, the construction of an LBM scheme near the boundary of grids with different spatial steps inevitably requires data interpolation, which can reduce the LBM approximation order and lead to violation of conservation laws. In this work, for the first time, we have developed and tested a method for constructing an athermal node-based LBM on non-uniform grids without interpolation, with the same time step for grids of different scales. The method based on a two-stage transformation of populations corresponding to different on-grid stencils.
Zones of Privacy in Letters Between Women of Power: Elizabeth I of England and Anna of Saxony
Authors: Neighbors Dustin , Käfer Natacha Klein
Published: October 2022

The present article explores how women of power engaged in diplomatic efforts via forms of epistolary privacy by analysing private letters between Elizabeth I and Anna of Saxony in the late 1570s and early 1580s. Through a close examination of how their exchanges moved from very public matters to more personal requests, the authors show how early modern notions of privacy offered strategic communication prompts that could be used effectively by women in political negotiations. The intersection between these zones of privacy with the very public matters being addressed in Elizabeth’s and Anna’s epistolary exchange makes explicit how noble women could develop their own private politics, becoming active agents of diplomacy even in periods of extreme religious and political turmoil through personal connections within female noble circles.
Community-Based COVID-19 Vaccine Clinics in Medically Underserved Neighborhoods to Improve Access and Equity, Philadelphia, 2021–2022
Authors: Klusaritz Heather , Paterson Emily , Summers Courtney , Al-Ramahi Nida , Naseer Nawar , Jeudin Helena , Sydnor Yuhnis , Enoch Maurice , Dollard Nieemah , Young Kevin D. , Khan Neda , Henne Jeffrey , Doubeni Anna , Kasbekar Nishaminy , Gitelman Yevgeniy , Brennan Patrick J. , Bream Kent , Cannuscio Carolyn C. , Wender Richard C. , Feuerstein-Simon Rachel
Published: October 2022

Vaccination remains key to reducing the risk of COVID-19–related severe illness and death. Because of historic medical exclusion and barriers to access, Black communities have had lower rates of COVID-19 vaccination than White communities. We describe the efforts of an academic medical institution to implement community-based COVID-19 vaccine clinics in medically underserved neighborhoods in Philadelphia, Pennsylvania. Over a 13-month period (April 2021–April 2022), the initiative delivered 9038 vaccine doses to community members, a majority of whom (57%) identified as Black. (Am J Public Health. 2022;112(12):1721–1725. https://doi.org/10.2105/AJPH.2022.307030 )
Knowledge and Practice of Pinworm Infection in Preschool Children, Jiangsu Province, China, 2019–2020
Authors: Mao Fanzhen , Yang Yougui , Zhang Qiang , Ding Xin , Xu Xiangzhen , Chen Yuying , Dai Yang , Cao Jun
Published: October 2022

We conducted a two-year (2019–2020) longitudinal study in Jiangsu Province, China to analyze risk factors of pinworm infection and evaluate the effect of behavior change communication–based (BCC-based) interventions in preschool children. The positive rate of pinworm infection was higher in private preschool (2%) than in public preschool (0.24%). Poor sanitation behaviors were risk factors among private preschool children. BCC-based intervention could improve knowledge and practice and reduce pinworm infection. This study may help fill in gaps in pinworm control. (Am J Public Health. 2022;112(12):1716–1720. https://doi.org/10.2105/AJPH.2022.307067 )
Controlling Shareholder Pledges and Cost of Equity Capital: Analyzing Empirical Evidence from A-share Listed Companies
Authors: Guo Cheng , Rong Huang , Yang Zhaiting , Sindakis Stavros , Aggarwal Sakshi
Published: October 2022

With the constant increase in China’s stock pledge transactions, controlling shareholders’ equity pledges may result in inadequate investment, which government regulatory authorities, investors, and financial management departments should be aware of. Taking China’s A-share listed companies from 2013 to 2019 as a sample, this paper examines the impact of controlling shareholder pledge on equity capital cost. It is found that the equity capital cost of listed companies increases significantly after controlling shareholder pledge, and high-quality audit reports help reduce the influence of controlling shareholder pledge on it. In addition, the mechanism test shows that controlling shareholder pledge impacts the equity capital cost by reducing stock liquidity and increasing the tunneling behavior of large shareholders. Further research shows that under controlling shareholder pledges, improving the quality of information disclosure can help reduce the equity capital cost, while stock price risk can increase the equity capital cost.
Urban tree composition is associated with breeding success of a passerine bird, but effects vary within and between years
Authors: Jensen Johan Kjellberg , Ekroos Johan Edvard , Watson Hannah , Salmón Pablo , Olsson Peter , Isaksson Caroline
Published: October 2022

Birds breeding in urban environments have lower reproductive output compared to rural conspecifics, most likely because of food limitation. However, which characteristics of urban environments may cause this deficiency is not clear. Here, we investigated how tree composition within urban territories of passerine birds is associated with breeding probability and reproductive success. We used seven years of data of breeding occupancy for blue and great tits (Cyanistes caeruleus; Parus major) and several reproductive traits for great tits, from 400 urban nest boxes located in five parks within the city of Malmö, Sweden. We found that tits, overall, were less likely to breed in territories dominated by either non-native trees or beech trees. Great tit chicks reared in territories dominated by non-native trees weighed significantly less, compared to territories with fewer non-native trees. An earlier onset of breeding correlated with increased chick weight in great tits. Increasing number of common oak trees (Quercus robur) was associated with delayed onset of breeding in great tits. Notably, as offspring survival probability generally increased by breeding earlier, in particular in oak-dominated territories, our results suggest that delayed onset of breeding induced by oak trees may be maladaptive and indicate a mis-match to this food source. Our results demonstrate that tree composition may have important consequences on breeding success of urban birds, but some of these effects are not consistent between years, highlighting the need to account for temporal effects to understand determinants of breeding success and inform optimal management in urban green spaces.
Computer aided drug design to generate a new antibiotic family
Authors: Barden Christopher , Wu Fan , Lu Erhu , Sun Shengguo , Taylor Marcia , Rushton Annette , Meek Autumn , Reddy Alla , Doyle Lisa , Sagamanova Irina , Sivamuthuraman Kovilpitchai , Boudreau Robert ,   J. Pedro Fernández-Murray1, Williams Jason , Byers David , Weaver Donald , McMaster Christopher
Published: October 2022

Using computer aided drug design we developed a new antibiotic class with a unique structure versus holo-acyl carrier protein synthase (AcpS). AcpS is a highly conserved enzyme essential for bacterial survival that catalyzes the first step in lipid synthesis. There are no current antibiotics targeting AcpS making this drug development program unique. We synthesized a library of >700 novel compounds targeting AcpS, from which 37 inhibit bacterial growth in vitro at ≤2 ug/ml. We demonstrate that compounds from this class have broad Gram positive activity including efficacy against clinically relevant multi-drug resistant strains in vitro and in animal models of infection in vivo. In addition, compounds from this new antibiotic family synergize with colistin versus multi-drug resistant Gram negative species. This new antibiotic family could form the basis for several multi-drug resistant antimicrobial programs.
How is China's energy green consumption revolution progressing? A comprehensive evaluation method based on entropy-weighted TOPSIS method
Authors: Zou Tong , Guo Pibin , Wu Qinglong
Published: October 2022

The Energy Green Consumption Revolution (EGCR) is an important sub-project of China's ongoing energy transition. Majority of the current studies on energy transition focused on the dynamics of the interaction between energy consumption and socio-technical elements such as economy, technology, environment, and institutions, and the transformation of energy consumption behavior, while only a few mentioned the crucial question regarding the EGCR progressing in China. This paper builds an integrated energy-economy-society-environment assessment framework and evaluates the progress of China's EGCR at the national, regional and inter-provincial levels using the entropy-weighted TOPSIS method. The evaluation results revealed that the overall progress of China's EGCR is stagnant, showing a stepped evolution of high level in the eastern region, medium level in the central region, and low level in the western region, with a huge gap in the progress of reform among provinces.
Analytical modeling of junction capacitance using Trapezoidal Approximation for source and drain Engineered Partially depleted Silicon on Insulator.
Authors: Baby Sumi , Pradeep Anju , U.S Shikha
Published: October 2022

Junction capacitance variation in Source-Drain Engineered Partially Depleted Silicon On Insulator(SDE-PDSOI), due to the geometry effects of source and drain are discussed in this paper. Reduction in sidewall junction capacitance at saturation is caused by reduced charge due to geometrical variation of source and drain. Junction capacitance is modeled and validated with numerical simulations. Trapezoidal approximation is applied to extract the depletion width and the junction capacitance is evaluated. Modulation of the depletion width with varying potential along the channel thickness is also presented.
Elucidation the by-products and toxicity assessment the treated solution of "10, 11 dihydro2 10 hydroxy carbamazepine" after electrochemical degradation process.
Authors: Mussa Zainab , Al-Qaim Fouad
Published: October 2022

In both deionized water and effluent wastewater, the electrochemical degradation kinetics of 10, 11 dihydro-10 hydroxy carbamazepine (HDX-CBZ) utilizing graphite-PVC composite as anode were evaluated. For the purpose of testing and validating a kinetic model for the oxidation of HDX-CBZ by the electrochemical oxidation process, the effects of the initial concentration of HDX-CBZ, chloride ion (Cl) loading, type of sample, applied voltage, hydrogen peroxide and pH were identified. The outcomes showed that HDX-CBZ electrochemical oxidation rates were pseudo-first-order kinetics. Depending on the operating conditions, the rate constant values varied from 0.0022 to 0.0483 min -1 . Due to the high applied voltage of 10 V, high energy consumption of 0.667 kWh g -1 HDX-CBZ was observed so it was not taken into account in this investigation. The primary by-products that arise from the electrochemical degradation of HDX-CBZ using graphite-PVC composite as anode in aqueous matrices were clarified using liquid chromatography time-of-flight mass spectrometry (LC-ToF/MS). At various incubation times, the toxicity of HDX-CBZ and its by-products against E. coli bacteria was evaluated.
An Evaluation of the Uric Acid and Hematological Parameters in Patients with Nodal Hand Osteoarthritis
Authors: Enginar Ayse Unal
Published: October 2022

Objective: To compare patients with symptomatic nodal hand osteoarthritis (OA) with a control group in respect of inflammation parameters, uric acid, and hematological parameters.
Methods:The study included 50 post-menopausal female patients diagnosed with symptomatic nodal hand OA and a control group of 50 post-menopausal females. Patient data including age, monocyte, neutrophil, lymphocyte, and thrombocyte counts, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, uric acid level, and the Kellgren-Lawrence (KL) score obtained from evaluations of hand radiographs, were recorded retrospectively from the hospital information system. The neutrophil-lymphocyte ratio (NLR), thrombocyte-lymphocyte ratio (PLR) and monocyte-lymphocyte ratio (MLR) were calculated. The data were compared between the two groups.
Results: Age, monocyte, neutrophil, lymphocyte, and thrombocyte counts, NLR, PLR, MLR, ESR, CRP, and uric acid level were compared. With the exception of MLR and ESR, no statistically significant difference was determined between the two groups. The MLR was determined to be statistically significantly higher in the control group than in the patient group (p:0.024). The ESR was determined to be statistically significantly higher in the patient group than in the control group (p<0.001). When patients with a KL score of 2 and 3 were compared, with the exception of age, no other difference was determined. Patients with a KL score of 3 were seen to be significantly older (p:0.032).
Conclusions: ESR was determined to be significantly higher in patients with symptomatic nodal OA. Clarification of the relationship between inflammation, uric acid, and hand OA, which is a heterogeneous disease, will be useful in the follow-up and treatment of patients.
Real–World outcomes of transjugular intrahepatic portosystemic shunt combined with embolization: A multicenter retrospective study
Authors: Zhao Lianhui , Wu Qiong , Wang Lifen , Xia Yifu , Tie Jun , Xu Jiao , Wu Hao , Wei Bo , Zhuge Yuzheng , Chen Chao , Sun Xiubin , Zhang Chunqing , Wang Guangchuan
Published: October 2022

Background and aims

Transjugular intrahepatic portosystemic shunt (TIPS) combined with embolization (TIPS + E) in the control of variceal bleeding still remains controversial. This study aimed to explore the clinical outcomes of TIPS + E and present evidence for guideline recommendations in a real–world cohort.

Methods

In this multicenter retrospective cohort, 2077 cirrhotic patients received TIPS ± E (631 in TIPS alone and 1446 in TIPS + E) were enrolled between January 2010 and June 2020, with a median follow–up time of 32.5 (19.3, 56.6) months. The primary outcome was rebleeding, and the secondary outcomes were hepatic encephalopathy (HE), survival, recompensated survival (R–survival), further–decompensated rates, and post–further–decompensated survival (PFD–survival).

Results

The rebleeding rate was similar between TIPS and TIPS + E group (P = 0.51). TIPS + E had a trend toward decreasing HE rates comparing to TIPS alone (P = 0.20). In addition, TIPS + E significantly improved survival comparing to TIPS (P = 0.006). Besides, TIPS + E group had a significant lower further-decompensated rate than TIPS (P = 0.04). For prognosis, TIPS + E also improved R–survival (P = 0.036) and PFD–survival (P = 0.02) comparing to TIPS alone, respectively.

Conclusion

Based on the present real–world data, TIPS + E showed efficacy in control of rebleeding, with a trend towards decreasing HE, which significantly improved survival and prognosis compared to TIPS alone.
Gapless superconductivity in Nb thin films probed by terahertz spectroscopy
Authors: Lee Ji Eun , Choi Joonyoung , Jung Taek Sun , Kim Jong Hyuk , Choi Young Jai , Sim Kyung Ik , Jo Youn Jung , Kim Jae
Published: October 2022

Time reversal symmetry (TRS) breaking often generates exotic quantum phases in condensed matter. In superconductors, TRS breaking by an external magnetic field not only suppresses superconductivity but also leads to a novel quantum state called the gapless superconducting state. Here we show that magneto-terahertz spectroscopy provides us with a rare opportunity to access and explore the gapless superconducting state of Nb thin films. We present the complete functional form of the superconducting order parameter for an arbitrary magnetic field, for which a fully self-consistent theory is, surprisingly, yet unavailable. We observe a Lifshitz topological phase transition with a vanishing quasiparticle gap everywhere on the Fermi surface, whereas the superconducting order parameter smoothly crosses over from the gapped to the gapless regime. Our observation of the magnetic pair-breaking effects in Nb challenges traditional perturbative theories and opens a pathway to further exploring and manipulating the exotic state of gapless superconductivity.
Management of Left Ventricular Aneurysm-Induced Ventricular Tachycardia in Limited Resource Setting: A Case Report
Authors: Mendel Brian , Kohar Kelvin , Utama Karen Elliora , Pratiwi Yustin Putri , Retnita Anggun , Prakoso Radityo
Published: October 2022

Introduction
Left ventricular aneurysm (LVA) was associated with life threatening ventricular tachycardia as well as sudden cardiac death. In limited-resource setting, the management of this condition remains challenging.
Case presentation
A 43-year-old man was diagnosed with unstable ventricular tachycardia. Due to certain circumstance, we tried to convert the rhythm by modifying Amiodarone intravenous infusion to prevent the sudden fall of blood pressure. After 300 mg of infusion, the rhythm converted to sinus. Furthermore, in addition to heart failure symptoms, ST elevation and pathological Q wave in V3-V6 still persisted within 7 days of follow-up, indicating the likelihood of LVA.
Conclusion
Untreated MI may lead to a LVA that can induce unstable ventricular tachycardia and aborted with amiodarone.
Photodynamic therapy reduced the risk of malignant transformation of oral leukoplakia: a retrospective study in an ethnic Chinese cohort
Authors: Song Yansong , Tang Fan , Liu Jiaxin , Yang Dan , Wang Jiongke , Luo Xiaobo , Jiang Lu , Zhou Yu , Zeng Xin , Xu Hao , Dan Hongxia , Chen Qianming
Published: October 2022

Objectives: This study aimed to evaluate the effect of photodynamic therapy (PDT) on the risk of malignant transformation of oral leukoplakia (OLK).
Materials and methods: This retrospective cohort study involved 370 OLK patients diagnosed from 2015 to 2022, with a mean time of 48.7 months from onset to the end of follow-up. Kaplan-Meier survival analysis, univariate and multivariate COX proportional regression models were used to evaluate the effects of PDT on the risk of malignant transformation of OLK. Subgroup analyses were performed to explore the role of PDT in OLK patients with different clinical characteristics.
Results: Older age (adjusted HR=1.034, P=0.01) and non-homogeneous leukoplakia (adjusted HR=2.181, P=0.035) had higher risk of malignant transformation of OLK. Patients who had finished a complete course of PDT (adjusted HR=0.316, P=0.008) had a significant lower risk of malignant transformation, while those who hadn’t finished a complete course of PDT (adjusted HR=0.702, P=0.372) cannot be considered to have such a protective effect. In the subgroup analyses, PDT showed a significant protective effect on malignant transformation of OLK in patients with female gender, no smoking or drinking habits, non-homogeneous lesions, lesions on oral mucosa outside the dangerous region, and any grade of epithelial dysplasia.
Conclusions: A complete course of PDT could significantly reduce the risk of malignant transformation of OLK, especially in those patients with risk factors of malignant transformation.
Clinical Relevance: PDT showed potential to prevent malignant transformation of OLK. A complete course of PDT might be encouraged to achieve better clinical outcomes.