bluuebunny/crossref_metadata_2025 huggingface dataset:
Pesticide Exposure of Residents Living Close to Agricultural Fields in the Netherlands: Protocol for an Observational Study (Preprint)
Authors: Figueiredo Daniel M , Krop Esmeralda J M , Duyzer Jan , Gerritsen-Ebben Rianda M , Gooijer Yvonne M , Holterman Henk J , Huss Anke , Jacobs Cor M J , Kivits Carla M , Kruijne Roel , Mol Hans J G J , Oerlemans Arné , Sauer Pieter J J , Scheepers Paul T J , van de Zande Jan C , van den Berg Erik , Wenneker Marcel , Vermeulen Roel C H
Published: February 2021

BACKGROUND

Application of pesticides in the vicinity of homes has caused concern regarding possible health effects in residents living nearby. However, the high spatiotemporal variation of pesticide levels and lack of knowledge regarding the contribution of exposure routes greatly complicates exposure assessment approaches.

OBJECTIVE

The objective of this paper was to describe the study protocol of a large exposure survey in the Netherlands assessing pesticide exposure of residents living close (<250 m) to agricultural fields; to better understand possible routes of exposure; to develop an integrative exposure model for residential exposure; and to describe lessons learned.

METHODS

We performed an observational study involving residents living in the vicinity of agricultural fields and residents living more than 500 m away from any agricultural fields (control subjects). Residential exposures were measured both during a pesticide use period after a specific application and during the nonuse period for 7 and 2 days, respectively. We collected environmental samples (outdoor and indoor air, dust, and garden and field soils) and personal samples (urine and hand wipes). We also collected data on spraying applications as well as on home characteristics, participants' demographics, and food habits via questionnaires and diaries. Environmental samples were analyzed for 46 prioritized pesticides. Urine samples were analyzed for biomarkers of a subset of 5 pesticides. Alongside the field study, and by taking spray events and environmental data into account, we developed a modeling framework to estimate environmental exposure of residents to pesticides.

RESULTS

Our study was conducted between 2016 and 2019. We assessed 96 homes and 192 participants, including 7 growers and 28 control subjects. We followed 14 pesticide applications, applying 20 active ingredients. We collected 4416 samples: 1018 air, 445 dust (224 vacuumed floor, 221 doormat), 265 soil (238 garden, 27 fields), 2485 urine, 112 hand wipes, and 91 tank mixtures.

CONCLUSIONS

To our knowledge, this is the first study on residents’ exposure to pesticides addressing all major nondietary exposure sources and routes (air, soil, dust). Our protocol provides insights on used sampling techniques, the wealth of data collected, developed methods, modeling framework, and lessons learned. Resources and data are open for future collaborations on this important topic.

INTERNATIONAL REGISTERED REPORT

RR1-10.2196/27883
Isolation and Characterization of Two Virulent Phages to Combat Staphylococcus aureus and Enterococcus faecalis causing Dental Caries
Authors: Nasr-Eldin Mohamed A. , El-Dougdoug Noha K. , Elazab Yara H. , Esmael Ahmed
Published: February 2021

This study aimed to isolate and characterize bacteriophages, as a biocontrol agent, against certain antibiotic-resistant bacteria causing dental caries. Here, two dental caries-causing bacteria S. aureus and E. faecalis were isolated and characterized biochemically using the automated VITEK® 2 system. Antibiotic sensitivity pattern of the isolated dental caries bacteria was assessed against selection of antibiotics. The two isolates showed resistance against most of the tested antibiotics. To overcome this problem, two lytic phages vB_SauM-EG-AE3 and vB_EfaP-EF01 were isolated, identified, and applied to control the growth of S. aureus and E. faecalis, respectively. Phages were identified morphologically using TEM and showed that vB_SauM-EG-AE3 phage is related to Myoviridae and vB_EfaP-EF01 phage belongs to Podoviridae. The two phages exhibited high lytic activity, high stability, and a narrow host range. The one-step growth curve of phages showed burst sizes of 78.87 and 113.55 PFU/cell with latent periods of 25 and 30 minutes for S. aureus phage and E. faecalis phage respectively. In addition, the two phages showed different structural protein profiles and exhibited different patterns using different restriction enzymes. The genome sizes were estimated to be 13.30 Kb and 15.60 Kb for phages vB_SauM-EGAE3, vB_EfaP-EGAE1, respectively. Complete inhibition of bacterial growth was achieved using phages with MOIs of 103, 102 and 10 after 1, 3, 5, and 24 h of incubation at 37°C. Hence, this study indicates that the isolated bacteriophages are promising biocontrol agents that could challenge antibiotic-resistant dental caries bacteria to announce new successful alternatives to antibiotics.
COMBATENDO O MOSQUITO AEDES AEGYPTI: UMA PARCERIA SAÚDE E ESCOLA
Authors: Gomes Renara Meira , Da Silva Mirian Souza Pereira , Santos Cizélia Barreto , Damacena Jucilene de Jesus , Vieira Sheylla Nayara Sales
Published: February 2021

O objetivo é relatar o desenvolvimento de uma ação de promoção à saúde realizada entre escolares, voltada para o combate aos focos do mosquito Aedes Aegypti. Caracteriza-se por um estudo descritivo, exploratório, participativo, com base no relato de experiência, referente a uma atividade de educação em saúde envolvendo matérial lúdico, desenvolvido em uma escola municipal, tendo dezoito escolares como sujeitos constituintes. A atividade evoluiu de forma positiva, visto que o brinquedo lúdico proporcionou interação entre as crianças assistidas e o tema desenvolvido e discutido. É prioritário nesse momento, a intensificação das ações cruciais de conscientização, envolvimento e combate ao vetor para garantir o controle da doença em um futuro próximo. Desse modo, a adesão a essas propostas em ações preventivas certamente resultarão num cenário favorável para a redução significativa do número de incidência de casos e internações por dengue.
SEMÁFORO DO CORAÇÃO E BINGO CARDIOVASCULAR: TECNOLOGIAS EDUCATIVAS PARA PREVENÇÃO DE DOENÇAS CARDIOVASCULARES EM IDOSOS
Authors: Oliveira Luciane Silva , Frota Kairo Cardoso da , Braga Yandra Kelline Brandão , Cardoso Maria Aparecida Fernandes , Ponte Keila Maria de Azevedo
Published: February 2021

O objetivo do presente artigo é descrever a utilização das tecnologias educativas para prevenção do adoecimento cardiovascular em idosos: Semáforo do Coração e Bingo Cardiovascular. Trata-se de um relato de experiência, realizado em novembro de 2018, com um grupo de idosos de uma Unidade Básica de Saúde do município de Sobral-Ceará.  A educação em saúde foi desenvolvida através de uma oficina prática. Participaram 15 pessoas integrantes do grupo. O momento foi organizado nas seguintes fases: integração com o grupo e apresentação; investigação acerca de seus conhecimentos sobre cardiopatias através da tecnologia “Semáforo do Coração” e orientações acerca dos hábitos para a prevenção de doenças cardiovasculares através da tecnologia “Bingo Cardiovascular”. Evidenciou-se que o uso das tecnologias educativas favoreceram o processo de comunicação entre facilitadores e participantes, pois pode-se trabalhar a temática de forma lúdica e criativa, sem a necessidade de imposições, proporcionando a ressignificação do processo de aprendizagem. A elaboração e implementação das tecnologias educativas foram relevantes por instigar a criatividade dos facilitadores e facilitar o compartilhamento de conhecimentos.
ASSOCIAÇÃO DA COGNIÇÃO COM FATORES SOCIOEDEMOGRÁFICOS E QUALIDADE DE VIDA EM CRIANÇAS PORTADORAS DE FISSURA OROFACIAL NÃO SINDRÔMICA
Authors: Cavalcanti de Lima Ergellis Victor , Gomes Salles Ândrea , Da Silva Chaves Dayse , Baia da Costa Fernanda , Sampaio Souza Aloiso , Dantas de Almeida Marques Rossana Vanessa
Published: February 2021

Trata-se de um estudo quantitativo com 67 crianças, entre 05 e 11 anos, agrupadas da seguinte forma: A1 (portadores de fissura labiopalatina; n= 21), A2 (crianças normorreativas vinculadas a escola privada; n= 23) e A3 (crianças normorreativas vinculadas a escola pública; n=23), sendo A1 o grupo caso e A2 e A3 os grupos controles. Realizaram-se anamnese, avaliação cognitiva, verificação de prontuários, análise da qualidade de vida e avaliação da qualidade de saúde oral; com a finalidade de obter correlações. A distribuição da amostra foi semelhante a outros estudos. Em A1, a fissura transforame obteve relação numérica com a inteligência abaixo da média(n=5). O grupo A2 apresentou maiores pontuações socioeconômicas em contraponto a A1 e A3, sem relação com a cognição. No A2 o domínio da incapacidade social obteve relevância com a inteligência abaixo da média(p=0,005), o que não se observou nos demais domínios de qualidade de saúde bucal do mesmo grupo e do A1 e A2. Na qualidade de vida do A1, o domínio da autonomia apresentou números menores que o A2 e A3, sem correlação com os tipos de inteligência; com os demais domínios semelhantes a outros estudos. Logo, a cognição das crianças portadoras de fissura orofacial não sindrômica não apresentou relação significativa com qualidade de vida, qualidade de saúde oral e perfil socioeconômico. Evidencia-se, portanto, a importância do tratamento multiprofissional e o seu impacto na normatização da vida de uma criança fissurada.

Palavras chave: Fenda Labial; Qualidade de vida; Cognição; Criança.
COVID-19: ETIOLOGIA, ASPECTOS CLÍNICOS, DIAGNÓSTICO, TRATAMENTO E EPIDEMIOLOGIA
Authors: Sampaio Carla Jaqueline Silva
Published: February 2021

O novo coronavírus SARS-CoV2 é o agente causador da pandemia por Coronavirus Disease 2019 (COVID-19). Devido ao alcance e a gravidade da COVID-19, este trabalho objetiva realizar um levantamento das informações sobre a COVID-19, enfatizando aspectos como a patogênese, as manifestações clínicas, o diagnóstico e a epidemiologia, bem como os principais obstáculos ao enfrentamento da pandemia. Realizou-se o levantamento bibliográfico nas bases de dados MEDLINE, Biblioteca Virtual em Saúde, e PubMed utilizando palavras-chave “COVID-19”, “SARS-CoV2”, “Coronavírus”, “Síndrome respiratória” e “Gastrointestinal” nos idiomas inglês e português. A rápida transmissão do vírus tem sobrecarregado os sistemas de saúde em vários países, resultado do aumento súbito do número de casos e elevado número de óbitos. As medidas restritivas e preventivas têm sido relevantes na redução do número de casos confirmados da COVID-19. Entretanto, ainda existe a necessidade do desenvolvimento e distribuição de vacina, medicamentos e testes rápidos para melhor controle da pandemia.
A PRESENÇA DE COMORBIDADES PSIQUIÁTRICAS E RISCO DE SUICÍDIO EM USUÁRIOS DE SUBSTÂNCIAS PSICOATIVAS
Authors: Oliveira Eliany Nazaré , Lima Letícia Mara Cavalcante , Moreira Roberta Magda Martins , Andrade Carla Suyane Gomes , Campos Marcos Pires , Almeida Paulo César
Published: February 2021

Objetivou-se analisar a saúde mental de usuários de substancias psicoativas tendo como parâmetro a presença de comorbidades psiquiátricas e o risco de suicídio. Trata-se de uma pesquisa com abordagem quantitativa de caráter exploratório-descritivo realizada em um Centro de Atenção Psicossocial e na Estratégia Saúde da Família de um município da 11° Regional de Saúde do Ceará (11° CRES). Foram entrevistados 51 usuários de substâncias psicoativas, no período de fevereiro a junho de 2019, mediante formulário sociodemográfico; o Self-ReportingQuestionnaire, Escala questionário sobre a saúde do paciente ou para avaliação de depressão e o Índice de Risco de Suicídio. A maioria dos usuários do sexo masculino (n=33; 64,7%), com faixa etária de 31 a 50 anos (n=24; 47,0%) e pardos (n=36; 70,6%), com transtorno mental comum (n=28; 54,9%), episódio depressivo maior (n-24; 47,1%) e risco intermediário para o suicídio (n=25; 49,0%). Estes resultados sugerem que os usuários de SPA apresentam comorbidades psiquiátricas e estão mais vulneráveis aos riscos de suicídio. Neste contexto, recomenda-se um plano de cuidado integral e multiprofissional com estratégias de monitoramento das comorbidades existentes e o risco de suicídio.
DOAÇÃO DE SANGUE: UM ATO DE HUMANIZAÇÃO LIMITADO
Authors: Freire Meira Leandro
Published: February 2021

Objetivos: analisar a visão dos profissionais de saúde de dois serviços de hemoterapia e hemoderivados sobre do critério de doze meses em abstinência sexual para que Homens que fazem sexo com outros Homens, Bissexuais e suas parceiras, se tornem aptos para a doação de sangue; Metodologia: um estudo de caráter descritivo e exploratório e de corte transversal, onde os locais escolhidos para ser o campo de pesquisa foram um Hemocentro e um Banco de Sangue, ambos situados em um município do interior baiano. O Hemocentro recusou-se a assinar o Termo de Anuência do Gestor. Resultados: os profissionais concordam com as regras propostas pela portaria que regulamenta a doação de sangue no Brasil, porém também concordam que há necessidade de modificar alguns artigos da mesma, buscando regras mais rigorosas para a aptidão de novos doadores, mostra a opinião dos profissionais sobre uma possível mudança nas regras para que houvesse uma igualdade para todos diante do ato de doar sangue, unanimidade opinou por não alterar as regras e manter a inaptidão por 12 meses. Conclusão: A Enfermagem visa pelo reconhecimento desse público, sugerindo que seja levantada a consideração da possibilidade de reduzir o período de inaptidão temporária para no máximo 120 dias.Descritores: Doação de Sangue; Enfermagem; Saúde.
ESTIMULAÇÃO ELÉTRICA NEUROMUSCULAR NA DIÁSTASE, FLACIDEZ E TROFISMO DA MUSCULATURA ABDOMINAL: UMA REVISÃO SISTEMÁTICA
Authors: Camilo Izabela Rodrigues , Silva Pâmela da , Mata Tainara Buliani da , Peres Celeide Pinto Aguiar , Bertolini Gladson Ricardo Flor
Published: February 2021

Objetivo: Realizar uma revisão sistemática da literatura, analisando os estudos que apontem os efeitos da eletroestimulação na diástase abdominal, flacidez e hipotrofismo da musculatura abdominal. Métodos: Para tanto, foi realizada a busca de artigos experimentais e ensaios clínicos com base nas publicações acessíveis nas bases de dados MEDLINE/PubMED, SciELO, PEDro e Google acadêmico, incluindo no estudo artigos relacionados ao tema proposto e que tinham como objetivo de estudo a influência da eletroterapia no tratamento da Diástase Abdominal (DA) e/ou flacidez da musculatura abdominal, com artigos disponíveis na integra,  nos idiomas português e inglês, publicados no período de 2002 a 2017. Foram excluídos do estudo, artigos que não se encaixavam a esses critérios e que utilizassem como terapia técnicas não existentes nas práticas da Fisioterapia; por utilizarem a eletroacupuntura e que fossem revisão de literatura. As buscas foram realizadas utilizando como palavras-chaves “Diástase”, “Eletroterapia”, “Abdominal”, “Pós-parto” e “Flacidez. Resultados: a estimulação elétrica acompanhada ou não de um protocolo de exercícios físicos no uso do fortalecimento da musculatura abdominal e/ou diminuição da diástase abdominal apresentou resultados positivos. Conclusão: a utilização da Estimulação Elétrica Neuromuscular é eficaz para diminuir a diástase abdominal e flacidez e melhora a hipotrofia muscular.
INTOXICAÇÃO POR OPIOIDE (METADONA): RELATO DE CASO
Authors: Oliveira Erivan de Souza , Liberato Francisco Leandro Rocha , Romeu Geysa Aguiar , Morais Arlandia Cristina Lima Nobre de
Published: February 2021

A intoxicação pode ser caracterizada como uma manifestação clínica, que apresenta sinais e sintomas causados por efeitos nocivos no organismo vivo do individuo da decorrência de interações com agentes tóxicos. Pode ser classificada como aguda ou crônica. O objetivo deste trabalho foi relatar um caso de intoxicação por opioide (metadona) acompanhado durante o estágio de toxicologia em um Centro de Informação e Assistência Toxicológica. Paciente J.D.M., 33 anos de idade, sexo feminino, ingeriu 20 comprimidos de metadona 5 mg, encontrava-se desacordada, irresponsiva a estímulos verbais e nociceptivos, taquicárdica (137 bpm), apresentava pupilas puntiformes, saturação de oxigênio 91% em ar ambiente e pressão arterial 91x54 mmHg. No entanto, ao quarto dia de internação hospitalar, a paciente apresentou curva de melhora clínica, sem sinais de intoxicação aguda. Conclui-se que éimportante que os sintomas iniciais de intoxicações sejam rapidamente identificados, pois favorece ao diagnóstico e tratamento rápido e efetivo.
CONCEPÇÃO DE PROFISSIONAIS DA ESTRATÉGIA SAÚDE DA FAMÍLIA SOBRE VIOLÊNCIA DOMÉSTICA CONTRA A MULHER
Authors: Santos Johandra Cristina Vieira , Silva Luana Ramos da , Dias Gilberto Alves , Machado Juliana Costa , Rodrigues Vanda Palmarella
Published: February 2021

A violência doméstica contra a mulher tem sido um problema cada vez mais discutido que acomete diferentes âmbitos da sociedade ligados a fatores culturais, sociais e econômicos, sendo caracterizada como um importante problema de saúde pública. O objetivo do estudo foi descrever as representações sociais de profissionais de saúde que atuam no âmbito da Estratégia Saúde da Família (ESF) sobre a violência doméstica contra a mulher. Pesquisa descritiva de natureza qualitativa, embasada na Teoria das Representações Sociais, com 24 profissionais de Unidades de Saúde da Família, utilizando o software IRAMUTEq e Análise de Conteúdo Temática. Foram apreendidos o entendimento sobre o conceito e as formas de violência doméstica contra a mulher entre os profissionais da ESF. Nesse sentido, estudos nessa visão demonstram a necessidade de que profissionais da atenção básica possam identificar e notificar melhor casos de violência doméstica contra a mulher em suas unidades.
Reflex sympatho-vagal coactivation and concealed QTc prolongation: Lessons from hERG-blockers and long QT syndromes type 1 and type 2
Authors: Champéroux Pascal , Fares Raafat , Jude Sebastien , Maleysson Vincent , Richard Serge , Guennec Jean-yves Le , Thireau Jerôme
Published: February 2021

Background and Purposes: Several hERG blocking molecules known for their
propensity in triggering Torsades de Pointes (TdP) were reported as
increasing High Frequency QT oscillations (HFQT). This effect was found
as reflecting a sympatho-vagal coactivation. The present work aims to
characterise the mechanism(s) leading to this particular state of the
autonomic nervous system. Experimental approach: Effects of 20 hERG
blockers including 15 torsadogenic molecules were assessed by telemetry
in beagle dogs. Electrocardiogram and stroke volume modelled from the
pulse contour method were analysed at the first dose level causing
either QTc prolongation and/or HFQT increase. Cardiac autonomic control
was analysed using the High Frequency Autonomic Modulation (HFAM) model
in dogs and in untreated genotyped LQT1 and LQT2 individuals, for
comparison. Key results: The sympatho-vagal coactivation induced by
torsadogenic molecules is elicited by reflex compensatory mechanisms in
response to changes in stroke volume or cardiac output related to
hemodynamic off-targets and/or QT prolongation. QTc prolongation was
concealed or markedly blunted by the sympathetic component activation in
a large proportion of tested torsadogenic drugs. Sympathetic reflex
mechanisms in LQT patients similar to that found for dofetilide was also
revealed in both patients exhibiting QTc prolongation and concealed QTc
prolongation, irrespective to LQT type. Conclusions and implications:
QTc prolongation and/or drug-induced hemodynamic side effects enhance
beat to beat ventricular repolarisation variability via sympatho-vagal
reflex compensatory mechanisms. Considering the sympathetic reflex
component via analysis of HFQT oscillations dramatically improves
prediction, sensitivity and specificity of drug induced Torsades de
pointes risk assessment.
Leptin promoted glycolytic metabolism to induce DCs activation via STAT3-HK2 pathway
Authors: Ye Yunshan , Bai Ziran , Ye Xiaokang , Yuan Bo , Tang Yawei , Jing Wei , Jin Minli , Wang Guan , li xia
Published: February 2021

Leptin is over-secreted in many autoimmune diseases, which can promote
dendritic cells (DCs) maturation and up-regulate the expression of
inflammatory cytokines, but the underlying mechanisms are not fully
elucidated. Considering the major role of leptin in maintaining energy
balance and the significant role of glycolysis in DCs activation, our
study aims to investigate whether leptin promotes the activation of DCs
via glycolysis and its underlying mechanisms. We demonstrated that
leptin promoted the activation of DCs, including up-regulating the
expression of co-stimulatory molecules and inflammatory cytokines,
enhancing the proliferation and T helper 17 (Th17) cell ratio in
peripheral blood mononuclear cells (PBMC) co-cultured with
leptin-stimulated DCs. Leptin also enhanced DCs glycolysis with
increased glucose consumption, lactate production, and the expression of
hexokinase 2 (HK2). In addition, the activation of DCs stimulated by
leptin could be inhibited by the glycolysis inhibitor 2-DG. To explore
the signaling pathways involved in leptin-induced HK2 expression, we
observed that only the inhibitors of STAT3 (NSC74859) could repress the
enhancement of HK2 triggered by leptin stimulation. Therefore, our
results indicated that leptin promoted glycolytic metabolism to induce
DCs activation via STAT3-HK2 pathway.
Deactivation of left ventricular assist device (LVAD) after recovery of cardiac function: a case report
Authors: ALKATTAN HANI , Kjellman Ulf , Selimovic Nedim , Omrani Ahmed Al , Alghamdi Abdullah
Published: February 2021

Recovery of heart function during support with durable LVAD is uncommon,
and there are few reports of cases that address the issue of eliminating
the LVAD without the need for a heart transplant. Radical surgical
removal of the LVAD may cause distortion of left ventricular cavity and
thus affect its function, in addition to the associated risks of the
operation. Innovative ways to de-activate the LVAD, relying mainly on
implantation of vascular plugs in the outflow graft have been used. Few
reports have shown the success of this method. In this case report, we
review the story of a young patient with advanced heart failure, who
underwent LVAD implantation, and after 6-month, there was a dramatic
improvement of heart function that enabled successful de-activation of
the device.
The dynamic analysis on a class of stochastic impulsive equations with doubly weighted pseudo almost automorphic coefficients on time scales
Authors: Zhu Ping
Published: February 2021

Devoting to exploring the translation invariance and convolution
invariance of doubly weighted pseudo almost automorphic stochastic
processes with impulses on time scales proposed in this paper. Based on
these results, taking advantage of a new approach to obtain the
existence and uniqueness of the doubly weighted pseudo almost
automorphic solutions to a class of stochastic nonlinear impulsive
equations on time scales, which enrich the dynamics of doubly weighted
pseudo almost automorphic stochastic processes. Finally, an example is
researched to illustrate our conclusions.
Sistem Pengiriman Data dan Tampilan Simulasi Dinamika Perubahan Tekanan Udara Matras Dekubitus dan Koordinat Lokasi Alat Memanfaatkan Web Server
Authors: Nugraha Christophorus K. Wisma , Pranjoto Hartono , Agustine Lanny
Published: February 2021

Pemantauan kesehatan pasien jarak jauh untuk menjelaskan kondisi kesehatan pasien telah mendorong manusia untuk membuat sistem pemantauan kesehatan berbasis IoT (Internet Of Things). Pemantauan dirasa penting untuk pasien yang berbaring di kasur dan tidak bergerak dalam jangka waktu yang lama, karena kondisi tersebut dapat menimbulkan ulkus dekubitus. Untuk mencegah masalah tersebut digunakan matras pereduksi dekubitus yang mengubah titik tumpu pada kulit secara berkala. Ada kondisi saat matras mengalami malafungsi, dan matras tidak lagi mengubah titik tumpu pada kulit secara berkala. Untuk itu perlu adanya pemantauan tekanan kantung udara matras sehingga kondisi tersebut bisa diatasi. Raspberry Pi 3 menjalankan simulasi perubahan siklus tekanan kantung udara pada matras secara periodik. Data simulasi tersebut akan dikirimkan ke server menggunakan modul GPS/GPRS SIM868 dan akan disimpan dalam database. Lokasi alat dapat diketahui dengan menggunakan modul GPS yang terintegrasi dalam modul GPS/GPRS SIM868. Dalam halaman web ditampilkan simulasi kembang kempis kantung udara matras yang diindikasikan dengan warna. Modul GPS/GPRS SIM868 dapat berkomunikasi dengan Raspberry Pi dan dapat mengirimkan data simulasi perubahan siklus tekanan udara pada matras. Pengujian tampilan halaman web dengan siklus simulasi kembang kempis kantung udara dengan indikasi perubahan warna pada matras sudah sesuai dengan data simulasi tekanan kantung udara yang dikirimkan dari Raspberry Pi ke database.
APLIKASI HEALTH BELIEF MODEL DALAM PENANGANAN PANDEMI COVID-19 DI PROVINSI DKI JAKARTA
Authors: Suryani Angela Oktavia , Purwodiharjo Otty Mulijaty
Published: February 2021

Tulisan berikut ini hendak menyajikan permasalahan di masyarakat DKI Jakarta terkait belum berhasilnya pelaksanaan program pencegahan penyebaran COVID-19 terutama penerapan PSBB dan usulan strategi pemecahannya dengan menggunakan pendekatan Health Belief Model (HBM). HBM merupakan pendekatan psikologi sosial yang menekankan persepsi individu sebagai kunci keberhasilan dilaksanakannya perilaku kesehatan. Persepsi-persepsi kunci dalam model ini antara lain adalah persepsi kerentanan individu untuk tertular COVID-19, persepsi keparahan COVID-19 dan konsekuensi yang akan diderita warga apabila terjangkit penyakit ini, persepsi manfaat melakukan PSBB, persepsi mengenai hambatan pelaksanaan PSBB, self-efficacy warga untuk berhadapan dengan COVID-19, serta sinyal-sinyal terlaksananya perilaku PSBB. Pengamatan lapangan yang dilakukan melalui analisis berita menunjukkan bahwa warga Jakarta masih memiliki persepsi-persepsi yang beragam sehingga belum dapat ditentukan persepsi mereka tergolong tinggi, rendah, positif, atau negatif. Dalam tulisan ini, paparan berbagai persepsi dikemukakan. Hasil analisis data menunjukkan bahwa permasalahan terjadi di semua persepsi kunci, terutama di persepsi hambatan. Hambatan yang mendasar terkait dengan belum efektifnya PSBB adalah dampak ekonomi. Dalam strategi, penulis mengusulkan adanya kampanye sosial kesehatan dengan menggunakan pendekatan positive reinforcement yang dilaksanakan secara rutin dan terbarukan untuk memberikan informasi yang akurat dan menimbulkan rasa aman dan nyaman pada warga. Selain itu disarankan pula pemerintah memberikan penghargaan ataupun insentif bagi para tenaga medis dan pihak-pihak lain yang secara aktif mendukung program pencegahan penyebaran COVID-19 ini.
Comparison of the Accuracy of WhipPredict to That of a Modified Version of the Short-Form Örebro Musculoskeletal Pain Screening Questionnaire to Predict Poor Recovery After Whiplash Injury
Authors: Sterling Michele , Ritchie Carrie , Rebbeck Trudy , Cameron Ian D. , Griffin Alex , Jagnoor Jagnoor , Nicholas Michael , Nguyen Ha , Warren Jacelle
Published: February 2021

Objective

To compare the accuracy of a whiplash-specific risk screening tool (WhipPredict) with that of the modified generic short-form Örebro Musculoskeletal Pain Screening Questionnaire (SF-ÖMPSQ) for predicting poor recovery in patients following whiplash injury.

Study Design

Inception cohort study.

Methods

Two hundred two participants with acute whiplash completed the WhipPredict and modified SF-ÖMPSQ at baseline. Poor recovery was measured at 6 and 12 months using the Neck Disability Index (greater than 10%), numeric pain-rating scale (greater than 3/10), global perceived recovery (less than +4), and inability to return to preinjury work level. Accuracy statistics were calculated to predict poor recovery.

Results

Seventy-one percent (n = 143) of participants completed the 6-month assessment and 56% (n = 113) completed the 12-month assessment. At baseline, agreement between the WhipPredict and modified SF-ÖMPSQ was fair (prevalence-adjusted and bias-adjusted κ = 0.26; 95% confidence interval: 0.12, 0.39). Depending on the outcome, 20% to 72% of people had not recovered at 6 months and 12% to 71% had not recovered at 12 months. At 6 and 12 months, the WhipPredict tool showed high sensitivity (88%–96%) and low specificity (all outcomes less than 31%) on all 4 separate outcomes. The modified SF-ÖMPSQ showed moderate sensitivity (67%–75%) for the Neck Disability Index, numeric pain-rating scale, and global perceived recovery, high sensitivity for return to work (81%–90%), and moderate specificity (54%–77%) for all 4 outcomes.

Conclusion

Both tools showed acceptable accuracy in predicting poor recovery. The WhipPredict tool is recommended to correctly identify patients who will not recover but may falsely classify those who recover well. Using the modified SF-ÖMPSQ will result in fewer patients falsely categorized as being at risk of poor recovery and may result in some people being undertreated. J Orthop Sports Phys Ther 2021;51(5):207–215. Epub 19 Feb 2021. doi:10.2519/jospt.2021.9987
Safety and Environmental Management Systems (SEMS) Audit Methodology
Authors: Williams Charlie , Chawla Om
Published: February 2021

Introduction

In the United States, the Bureau of Safety and Environmental Enforcement (BSEE) requires an offshore lease operator to implement a Safety and Environmental Management System (SEMS), and to have it audited at least once every 3 years to evaluate its compliance to the regulatory requirements detailed in 30 CFR 250, Subpart S.

The first round of these SEMS audits, which concluded in 2013, was executed using varying audit styles – from system audits through to compliance audits. These varying audit styles, in turn, lead to differing types output, levels of detail, format and presentation.These diverse approaches may have been due, at least in part, to disparities in the expectations of stakeholders, differing interpretations of the use of the Center for Offshore Safety's (COS) SEMS Audit Protocol tools, use of other audit protocols, the experience-level of individual auditors, and the newness of the regulation.

System audits are intended to be a holistic assessment of a system, its elements, and how the elements work together to achieve system objectives. Compliance audits, on the other hand, are intended to assess adherence to specific requirements.

This white paper proposes that both types of audits should be used in tandem to reduce risk and increase confidence that a management system, and its verification programs, is operating as designed and meeting regulatory and company requirements.
Is error detection helpful on IBM 5Q chips?
Authors: Vuillot Christophe
Published: February 2021

This paper reports on experiments realized on several IBM~5Q chips which show evidence for the advantage of using error detection and fault-tolerant design of quantum circuits. We show an average improvement of the task of sampling from states that can be fault-tolerantly prepared in the [4,2,2] code, when using a fault-tolerant technique well suited to the layout of the chip. By showing that fault-tolerant quantum computation is already within our reach, the author hopes to encourage this approach.
Quantum signaling to the past using P-CTCS
Authors: Ghosh Soumik , Adhikary Arnab , Paul Goutam
Published: February 2021

Closed Timelike Curves (CTCs) are intriguing relativistic objects that allow for time travel to the past and can be used as computational resources. In Deutschian Closed Timelike Curves (D-CTCs), due to the monogamy of entanglement, non-local correlations between entangled states are destroyed. In contrast, for Postselected Closed Timelike Curves (P-CTCs), a second variant of CTCs, the non-local correlations are preserved. P-CTCs can be harnessed for the signaling of non-orthogonal states to the past without a disruption of causality. In this paper, we take up signaling to the past and show a method of sending four non-orthogonal states to the past using P-CTCs. After constructing our signaling protocol, we study the causality violations that our protocol results in and put forward two consistency relations to prevent them.
Weak measurement for improving the efficiency of remote state preparation in noisy
Authors: Wang Ming-Ming , Qu Zhi-Guo
Published: February 2021

Quantum communication provides a new way for transmitting highly sensitive information. But the existence of quantum noise inevitably affects the security and reliability of a quantum communication system. The technique of weak measurement and its reversal measurement (WMRM) has been proposed to suppress the effect of quantum noise, especially, the amplitude-damping noise. Taking a GHZ based remote state preparation (RSP) scheme as an example, we discuss the effect of WMRM for suppressing four types of quantum noise that usually encountered in real-world, i.e., not only the amplitude-damping noise, but also the bit-flip, phase-flip (phase-damping) and depolarizing noise. And we give a quantitative study on how much a quantum output state can be improved by WMRM in noisy environment. It is shown that the technique of WMRM has certain effect for improving the fidelity of the output state in the amplitude-damping noise, and only has little effect for suppressing the depolarizing noise, while has no effect for suppressing the bit-flip and phase-flip (phase-damping) noise. Our result is helpful for improving the efficiency of entanglement-based quantum communication systems in real implementation.
Non-local universal gates generated within a resonant magnetic cavity
Authors: Delgado Francisco
Published: February 2021

Quantum Information is a quantum resource being advised as a useful tool to set up information processing. Despite physical components being considered are normally two-level systems, still the combination of some of them together with their entangling interactions (another key property in the quantum information processing) become in a complex dynamics needing be addressed and modeled under precise control to set programmed quantum processing tasks. Universal quantum gates are simple controlled evolutions resembling some classical computation gates. Despite their simple forms, not always become easy fit the quantum evolution to them. SU(2) decomposition is a mechanism to reduce the dynamics on SU(2) operations in composed quantum processing systems. It lets an easier control of evolution into the structure required by those gates by the adequate election of the basis for the computation grammar. In this arena, SU(2) decomposition has been studied under piecewise magnetic field pulses. Despite, it is completely applicable for time-dependent pulses, which are more affordable technologically, could be continuous and then possibly free of resonant effects. In this work, we combine the SU(2) reduction with linear and quadratic numerical approaches in the solving of time-dependent Schr\"odinger equation to model and to solve the controlled dynamics for two-qubits, the basic block for composite quantum systems being analyzed under the SU(2) reduction. A comparative benchmark of both approaches is presented together with some useful outcomes for the dynamics in the context of quantum information processing operations.
Super-activating quantum memory with entanglement
Authors: Guan Ji , Feng Yuan , Ying Mingsheng
Published: February 2021

Noiseless subsystems were proved to be an efficient and faithful approach to preserve fragile information against decoherence in quantum information processing and quantum computation. They were employed to design a general (hybrid) quantum memory cell model that can store both quantum and classical information. In this paper, we find an interesting new phenomenon that the purely classical memory cell can be super-activated to preserve quantum states, whereas the null memory cell can only be super-activated to encode classical information. Furthermore, necessary and sufficient conditions for this phenomenon are discovered so that the super-activation can be easily checked by examining certain eigenvalues of the quantum memory cell without computing the noiseless subsystems explicitly. In particular, it is found that entangled and separable stationary states are responsible for the super-activation of storing quantum and classical information, respectively.
Quantum collision-resistance of non-uniformly distributed functions: upper and lower bounds
Authors: Ebrahimi Ehsan , Unruh Dominique
Published: February 2021

We study the quantum query complexity of finding a collision for a function f whose outputs are chosen according to a non-uniform distribution D. We derive some upper bounds and lower bounds depending on the min-entropy and the collision-entropy of D. In particular, we improve the previous lower bound by Ebrahimi Targhi et al. from \Omega(2^{k/9}) to \Omega(2^{k/5}) where k is the min-entropy of D.
Ent: A Multipartite entanglement measure, and parameterization of entangled states
Authors: Hedemann Samuel R.
Published: February 2021

A multipartite entanglement measure called the ent is presented and shown to be an entanglement monotone, with the special property of automatic normalization. Necessary and sufficient conditions are developed for constructing maximally entangled states in every multipartite system such that they are true-generalized X states (TGX) states, a generalization of the Bell states, and are extended to general nonTGX states as well. These results are then used to prove the existence of maximally entangled basis (MEB) sets in all systems. A parameterization of general pure states of all ent values is given, and proposed as a multipartite Schmidt decomposition. Finally, we develop an ent vector and ent array to handle more general definitions of multipartite entanglement, and the ent is extended to general mixed states, providing a general multipartite entanglement measure.
Candidates for universal measures of multipartite entanglement
Authors: Hedemann Samuel R.
Published: February 2021

We propose and examine several candidates for universal multipartite entanglement measures. The most promising candidate for applications needing entanglement in the full Hilbert space is the ent-concurrence, which detects all entanglement correlations while distinguishing between different types of distinctly multipartite entanglement, and simplifies to the concurrence for two-qubit mixed states. For applications where subsystems need internal entanglement, we develop the absolute ent-concurrence which detects the entanglement in the reduced states as well as the full state.
Distributed synthesis of chains with one-way biphotonic control
Authors: Ozhigov Yuri
Published: February 2021

An example of a one-way distributed computation is given in which the use of entangled states of two photons to synchronize processes gives a benefit. The process of assembling polymer chains at two remote points is considered; the quality of the assembly is determined when they are superimposed on each other. The effect of using entangled states is almost 14 percents.
Channel fidelities for high-fidelity approach in KLM scheme
Authors: Oshima Kazuto
Published: February 2021

We study channel fidelity for the high-fidelity approach in the Knill-Laflamme-Milburn (KLM) scheme. We examine an optimal channel fidelity f_{opt} and identify the corresponding KLM ancilla state. In the limit of large n, where 2n is the number of the ancilla qubits, we find f_{opt}=1-{\pi^{2} \over 6n^{2}}+{2\pi^{2} \over 9n^{3}}. We see that as n increases f_{opt} approaches to 1 slightly faster than f=1-{2 \over n^{2}} which is the channel fidelity computed by Franson et. al. in the limit of large n. We also compute the channel fidelity for the ancilla state that gives a lower bound of success probability of quantum teleportation.
Improved reconciliation with polar codes in quantum key distribution
Authors: Lee Sunghoon , Park Jooyoun , Heo Jun
Published: February 2021

Quantum key distribution (QKD) is a cryptographic system that generates an information-theoretically secure key shared by two legitimate parties. QKD consists of two parts: quantum and classical. The latter is referred to as classical post-processing (CPP). Information reconciliation is a part of CPP in which parties are given correlated variables and attempt to eliminate the discrepancies between them while disclosing a minimum amount of information. The elegant reconciliation protocol known as \emph{Cascade} was developed specifically for QKD in 1992 and has become the de-facto standard for all QKD implementations. However, the protocol is highly interactive. Thus, other protocols based on linear block codes such as Hamming codes, low-density parity-check (LDPC) codes, and polar codes have been researched. In particular, reconciliation using LDPC codes has been mainly studied because of its outstanding performance. Nevertheless, with small block size, the bit error rate performance of polar codes under successive-cancellation list (SCL) decoding with a cyclic redundancy check (CRC) is comparable to state-of-the-art turbo and LDPC codes. In this study, we demonstrate the use of polar codes to improve the performance of information reconciliation in a QKD system with small block size. The best decoder for polar codes, a CRC-aided SCL decoder, requires CRC-precoded messages. However, messages that are sifted keys in QKD are obtained arbitrarily as a result of a characteristic of the QKD protocol and cannot be CRC-precoded. We propose a method that allows arbitrarily obtained sifted keys to be CRC precoded by introducing a virtual string. Thus the best decoder can be used for reconciliation using polar codes and improves the efficiency of the protocol.
Analisis dan Evaluasi File Storage and Backup di Diskominfo Data Center
Authors: Furkon Endang Amalia
Published: February 2021

Bencana adalah suatu kejadian yang sangat merusak dan tidak dapat diprediksi waktu terjadinya. Suatu fasilitas yang digunakan untuk menempatkan sistem komputer dan komponen-komponen terkaitnya, seperti sistem telekomunikasi dan penyimpanan data. Menurut Badan Nasional Penanggulangan Bencana (BNPB) Indonesia sangat rentan oleh bencana dikarenakan posisi Indonesia berada diatas tiga lempeng aktif dan cincin api. Reputasi Indonesia sebagai negara rawan bencana, juga tercatat dalam laporan The Atlas of the Human Planet 2017. Datanya menunjukkan, ancaman bencana alam telah meningkat dua kali lipat dalam 40 tahun terakhir seturut meningkatnya jumlah populasi. Diskominfo Jawa Barat adalah sebuah intansi yang bertugas melaksanakan urusan pemerintah daerah Jawa Barat di bidang komunikasi dan informatika berdasarkan asas otonomi, dekonsentrasi dan tugas pembantuan. Diskomifo memiliki data center yang berguna untuk kepentingan diskominfo itu sendiri dan SKPD (Satuan Kerja Perangkat Daerah) pemerintah provinsi Jawa Barat. Sebuah data center, harus di desain sebaik mungkin untuk menghindari gangguan kerusakan akibat bencana, gangguan ataupun kesalahan yang dapat menyebabkan kerusakan dari data center itu sendiri, maka dari itu harus dapat dihindari atau diminilisir dari dampak risiko yang terjadi dan menjamin availabilitas kelangsungan bisnis organisasi apabila terjadi gangguan atau bencana. Dalam penelitian ini dilakukan analisis terkait penilaian terhadap terjadinya risiko untuk mengetahui tingkat dampak risiko. Selain itu dalam dokumen ini juga dilakukan analisis dampak bisnis untuk mengetahui prioritas dari sistem informasi yang dimiliki organisasi, agar organisasi dapat lebih mengetahui sistem informasi yang mana yang menjadi prioritas utama ketika terjadi gangguan.
Diz oynağının osteoartritində kompleks terapiyanın effektivliyi
Authors: Ahmadov C.H  , Zamanov N.T.  , Nuriyev A. A.  , Ahmadova E.I.
Published: February 2021

İşin məqsədi. Tədqiqatın məqsədi diz oynağının osteoartritində (OA) kompleks terapiyanın klinik təcrübədə effektivliyini öyrənmək olmuşdur.Material və metodlar. Diz oynağının osteoartriti ilə 75 xəstə tədqiqata cəlb olunmuşdur. Xəstələr əsas dərman preparatı kimi NBL Qlükozamin Xondroitin MSM və qeyri-steroid iltihab əleyhinə preparatla Etodin - fortla əhatə olunmuşlar. Tədqiqata cəlb olunan xəstələrin yaşı 45-70 arasında tərəddüd etmişdir ki, xəstələrin 60-ı qadın (80,0%), 15-i kişi (20,0%) cinsinə aid olmuşdur. Xəstələrin orta yaşı; 60,0 ± 2,6 orta xəstəliyin davam müddəti isə 8,7 ± 2,8 il təşkil etmişdir. Xəstələr 3 qrupda təsnif olunmuşdur ki, I qrup xəstələr (25 nəfər) yalnız kombinə olunmuş NBL Qlükozamin Xondroitin MSM xondroprotektor, II qrup xəstələr (25 nəfər) xondroprotektorla qeyri-steroid iltihab əleyhinə preparatla birgə müalicə almışdır. III qrup xəstələrdə (25 nəfər) isə kalium- yodid və novakain elektoforez üsulu ilə kompleks müalicəyə qoşulmuşdur.Nəticələr. NBL Qlükozamin Xondroitin MSM alan I qrupda 12 həftəlik kurs müalicədən sonra 30% halda kafi qiymətləndirmə olmuşdur. II qrupda isə bu rəqəm 50% həddində tərəddüd etmişdir. III qrup xəstələrdə isə kalium- yodid və novakain elektoforez üsulu ilə kompleks müalicəyə qoşulmuşdur ki, bu qrupda ağrıların azalması 70 % halda müşahidə olunmuşdur.Yekun. Müalicənin sonunda ən yaxşı effekt III qrup xəstələrdə - elektroforezin qoşulduğu qrupda müşahidə olunmuşdur.
Covid-19 pnevmonyiası: diaqnostikasında və menecmentində radioloqun rolu
Authors: Sultanova M.J.
Published: February 2021

İşin məqsədi. İşin məqsədi COVİD-19 diaqnozu PCR (polimerazalı zəncirvari reaksiya) testi ilə təsdiq olunmuş xəstələrdə ağciyərlərdə baş verən dəyişikliklərin diaqnostikasında və dinamikasının izlənilməsində döş qəfəsi rentgenoqrafiya və komputer tomoqrafiya müayinələrinin imkanlarının öyrənilməsi olmuşdur.Material və metodlar. Tədqiqat Azərbaycan Tibb Universitetinin Tədris-Cərrahiyyə Klinikasında aparılmışdır. Tədqiqata 124 xəstənin döş qəfəsinin rentgenoqrafiya və 60 xəstənin komputer tomoqrafiya müayinələrinin nəticələri daxil edilmişdir. Hər iki müayinənin aparıldığı 30 xəstədə nəticələr müqayisəli dəyərləndirilmişdir.Nəticələr. Döş qəfəsi rentgenoqrafiya müayinələrində daha çox aşkar etdiyimiz əlamətə buzlu şüşə görüntüsü aid edilmişdir ki, bu da 74(60%) nəfərdə aşkar edilmişdir. Bundan bir qədər az 24(19%) xəstədə isə konsolidasiya sahələri vizuallaşmışdır. 26 xəstədə (21%) xəstədə rentgenoloji dəyərləndirilən dəyişiklik aşkar edilməmişdir. Zədələnmələr daha çox periferik ağciyər sahələrində (68%) və aşağı paylarda izlənilmiş (72%) və daha çox hallarda (56%) bilateral xarakter daşımışlar. 3(2%) xəstədə plevral effuziya aşkar edilmişdir. Komputer tomoqrafiya müayinəsində də, həmçinin daha çox aşkar etdiyimiz əlamətə buzlu şüşə görüntüsü aid edilmişdir ki, bu da 48 (80%) xəstədə aşkar edilmişdir. Bundan başqa, 21(35%) xəstədə isə konsolidasiya sahələri aşkar edilmişdir ki, bu da görüntülərdə buzlu şüşə görüntüsü ilə birlikdə vizuallaşmışdır. Digər səciyyəvi əlamətlərdən 25(42%) xəstədə plevral fibrotik bandlar, 9(15%) xəstədə düyünşəkilli buzlu şüşə görüntüsü və 12(20%) xəstədə vaskulyar genişlənmələr aşkar edilmişdir. 4(7%) xəstədə plevral effuziya izlənilmişdir. 12(20%) xəstədə komputer tomoqrafiya müayinəsində dəyişiklik aşkar edilməmişdir. Zədələnmələr daha çox periferik ağciyər sahələrində (86%) və aşağı arxa seqmentlərdə izlənilmiş (80%) və daha çox hallarda (60%) bilateral xarakter daşımışlar.Yekun. COVID-19 pnevmoniyasının diaqnostikasında və menecmentində radioloji müayinələrdə izlənilən əlamətlər yüksək informativliyə malikdir.Bu vacib məqamlar COVİD- 19 pnevmoniyası ilə məşğul olan bütün mütəxəssislər üçün əhəmiyyətlidir.