bluuebunny/crossref_metadata_2025 huggingface dataset:
“Thank you for Listening” Kaupapa Māori Methodology as a Facilitator of Culturally Safe Research With Māori Mothers Experiencing Perinatal Mental Illness
Authors: Meredith Cara , Haitana Tracy , McKerchar Christina , Pitama Suzanne
Published: December 2024

Māori are the Indigenous peoples of Aotearoa, New Zealand, and, similar to other Indigenous populations, face significant health inequities. Of concern, Māori mothers and birthing parents experience persistent and grave mental health inequities within the perinatal period relative to other ethnic groups. Indigenous research participants who have mental illness and who are also pregnant or in the early stages of parenting present intersecting ethical dilemmas for researchers working with research participants in situations of vulnerability. Given the known historical harms that culturally unsafe research has previously caused Indigenous peoples, it is crucial that research approaches with Indigenous mothers and birthing parents who have experienced mental illness are culturally safe and ethically sound. Kaupapa Māori research provides a framework to decolonise research processes and create the conditions for the cultural safety of the researcher and research participants. Kaupapa Māori research is grounded in a philosophy of relationship and a mutual recognition of the mana (dignity, prestige) of both researcher and participant. Engaging in culturally safe and responsive research with Māori can address power imbalances and ensure that the priorities of Māori communities are centred within the research. This paper details the application of a Kaupapa Māori research methodology used within qualitative research with Māori mothers and birthing parents experiencing perinatal mental illness and is structured in three parts. The first section situates Kaupapa Māori methodology in relation to the context of Māori mothers and birthing parents experiencing perinatal mental illness, providing a rationale for the research. The second section describes the application of Kaupapa Māori methodology within the research project. The third section discusses Kaupapa Māori methodology’s influence on research participants’ cultural safety through a case study format.
Augmenting research consent: should large language models (LLMs) be used for informed consent to clinical research?
Authors: Allen Jemima W , Schaefer Owen , Porsdam Mann Sebastian , Earp Brian D , Wilkinson Dominic
Published: December 2024

The integration of artificial intelligence (AI), particularly large language models (LLMs) like OpenAI’s ChatGPT, into clinical research could significantly enhance the informed consent process. This paper critically examines the ethical implications of employing LLMs to facilitate consent in clinical research. LLMs could offer considerable benefits, such as improving participant understanding and engagement, broadening participants’ access to the relevant information for informed consent and increasing the efficiency of consent procedures. However, these theoretical advantages are accompanied by ethical risks, including the potential for misinformation, coercion and challenges in accountability. Given the complex nature of consent in clinical research, which involves both written documentation (in the form of participant information sheets and informed consent forms) and in-person conversations with a researcher, the use of LLMs raises significant concerns about the adequacy of existing regulatory frameworks. Institutional Review Boards (IRBs) will need to consider substantial reforms to accommodate the integration of LLM-based consent processes. We explore five potential models for LLM implementation, ranging from supplementary roles to complete replacements of current consent processes, and offer recommendations for researchers and IRBs to navigate the ethical landscape. Thus, we aim to provide practical recommendations to facilitate the ethical introduction of LLM-based consent in research settings by considering factors such as participant understanding, information accuracy, human oversight and types of LLM applications in clinical research consent.
Trans-trapezium carpometacarpal dislocation of the thumb
Authors: Gao Yongbin , Xiong Ge , Chen Shanlin
Published: December 2024

We report a case series of trans-trapezium carpometacarpal dislocation of the thumb and propose a classification to help with decision-making for this injury.
The effect of caricaturing on the esthetic appeal of familiar faces, and its relation to simple proportion judgments
Authors: Anderson Andrew J. , Livingstone Margaret S.
Published: December 2024

It has been suggested that caricaturing enhances esthetic appeal, by making an image more strongly stimulate those areas of the brain encoding the subject's distinctive features than does the subject itself. However, some experimental work suggests that people prefer faces with proportions closer to average, or closer to a particular template. It might be that familiarity with the face is important if caricaturing is to increase the esthetic appeal of a likeness. Here we examined how automated caricaturing of photographs of nominal celebrities influenced judgments of esthetic appeal, and how familiarity with the celebrities affected these. Caricaturing monotonically decreased the esthetic appeal of the celebrity photographs, with subjects’ familiarity with the celebrity not influencing this relationship. The degree to which caricaturing influenced esthetic appeal was not correlated with judgments of relative spatial dimensions for a simple shape, either in a discrimination threshold experiment or a peak-shift experiment.
Intense fibroblast activation protein inhibitor localization around the site of embolized gastroduodenal artery in a patient with metachronous pancreatic adenocarcinoma: A potential pitfall in positron imaging
Authors: Abdlkadir Ahmed Saad , Alalawi Hasan , Al-Ibraheem Akram
Published: December 2024

68Gallium-Fibroblast activation protein inhibitor (68Ga-FAPI) positron emission tomography/computed tomography (PET/CT) is increasingly used for evaluating various epithelial neoplasms. Despite addressing some pitfalls, many remain unacknowledged. This report details a 77-year-old man with suspected pancreatic malignancy who underwent a 68Ga-FAPI PET/CT scan post-gastroduodenal coil embolization for upper gastrointestinal bleeding. The scan revealed intense 68Ga-FAPI uptake in the pancreatic body and tail malignancy and around the embolized gastroduodenal artery, indicating a healing process. This highlights the importance of understanding FAPI expression in recent surgical sites for accurate radiologic interpretation.
Adjudicating Registry Data: Benefits and Pitfalls—The ACTION Experience
Authors: Kwiatkowski David M. , Auerbach Scott , Niebler Robert A. ,   on behalf of the ACTION Adjudication Committee
Published: December 2024

The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry collects data and adjudicates adverse events on pediatric patients receiving mechanical circulatory support at participating centers. To date, the registry includes over 1500 patients from 48 centers. Data collected has been used for research publications, quality improvement projects, and the regulatory support of several ventricular assist devices. While this dataset is large and adjudicated, the registry has real limitations that may limit the interpretation of findings. A full understanding of potential biases and limitations allows researchers and clinicians to make meaningful conclusions from the patient population. This report reviews the strengths and limitations of the ACTION registry to ensure optimal utility among pediatric patients receiving mechanical circulatory support. It also suggests potential areas for improvement to facilitate best care of this vulnerable population.
Relationship Between Intensive Passive Data Signals and Patterns of Binge-Eating Behaviors: From a Dynamical-System Approach
Authors: Shi Qinxin , Thornton Laura M. , Kilshaw Robyn , Flatt Rachael E. , Butner Jonathan E. , Adamo Colin , Deboeck Pascal R. , Baucom Brian R. W. , Tregarthen Jenna , Argue Stuart , Bulik Cynthia M.
Published: December 2024

In this study, we investigate using passive data, specifically heart rate and actigraphy, for individuals with binge-type eating disorders such as bulimia nervosa (BN) and binge-eating disorder (BED). By applying dynamical-system theory and incorporating advancements in technology-based health care, we explored the relationship between passive data patterns as potential indicators of binge-eating episodes. Over 30 days, 1,019 participants with BN or BED symptoms used the Recovery Record app on iPhone and Apple Watches for real-time eating-behavior logging. Apple Watches simultaneously recorded heart rate and actigraphy. Results show no marked difference in heart and step averages 2 hr before a binge versus a control period. However, significant momentum and stability differences emerged when examining the changing dynamics leading up to a binge event. These findings suggest that the stability of step, rather than their average value, may serve as a detectable indicator of approaching binge events.
2024 IRSF Rett Syndrome Scientific Meeting June 18-19, 2024, Westminster, Colorado, USA
Authors: Garg Nupur , Broccoli Vania , Cobb Stuart , Meyer Kathrin , Pozzo-Miller Lucas
Published: December 2024

The 2024 International Rett Syndrome Foundation (IRSF) Rett Syndrome Scientific Meeting, held in Westminster, Colorado, gathered over 200 researchers and clinicians to discuss advancements in understanding and treating Rett syndrome (RTT). Key topics included MeCP2 biology, neuronal circuitry, therapeutic development, and clinical trial outcomes. The meeting reinforced the importance of collaborative research in unraveling RTT’s complex pathology and advancing treatment approaches. With promising therapeutic candidates in development, the conference underscored a growing hope for effective treatments, offering a path toward improving the quality of life for individuals with Rett syndrome and their families.
The Presence of Predatory and Open Access Journal Publications Among Canadian Plastic Surgery Residency Applicants
Authors: Keeler Adrianna , ElHawary Hassan , Tuen Young Ji , Courtemanche Rebecca , Gilardino Mirko S. , Arneja Jugpal S.
Published: December 2024

Introduction: As scientific publishing has transitioned online, open access and predatory publishers have surged. This study describes the frequency of publications in potentially predatory and open access journals among applicants to a Canadian plastic surgery residency program, and explores applicant characteristics associated with open access and predatory publishing. Methods: A retrospective review of plastic surgery resident applicants’ curriculum vitae (CVs) from 2015 to 2018 was performed. Published articles listed in CVs were reviewed by 2 authors to identify publication availability, publication year, and publisher. Open access publications were identified using the Directory of Open Access Journals. Predatory publications were identified using Beall's list of potentially predatory publishers. Published applicants’ characteristics were summarized. Applicant characteristics associated with open access and predatory publishing were explored using logistic regression. Results: Of the 186 applicants, 117 published 388 articles and were included in the final analysis. 156 (40.2%) articles were published in open access journals by 76 (40.8%) applicants. 14 (3.6%) articles were published in predatory journals by 14 (7.5%) applicants. Applicant characteristics associated with open access publishing included total number of publications (OR: 1.56, 1.18-1.93, P < .001) and presence of at least one post-baccalaureate degree (OR: 0.36, 0.13-0.95, P = .038). Only an applicant's total number of publications (OR: 1.25, 1.06-1.48, P = .010) was significantly associated with publishing in a predatory journal. Conclusion: These findings stress the importance of raising awareness within the plastic surgery community, including medical students, about the deceptive nature of predatory journals.
Salary Negotiation Role-Playing in Online Course Settings
Authors: Parks-Yancy Rochelle , Cooley Delonia
Published: December 2024

Preparing to negotiate salary is an important aspect of the employment process, given that compensation varies for different roles. Unfortunately, there are limited formal mechanisms for college students to learn how to negotiate salary. More often than not, students accept the first salary offer for post-collegiate employment without negotiating. This is due to several factors: lack of knowledge that salary negotiation is possible; lack of knowledge of how to negotiate; and possible fear that negotiation will cause job offer recission. However, negotiating salary is a critical skill for business school students. This is because it impacts their financial compensation throughout their professional lives. This exercise prepares students who were enrolled in an asynchronous online course to negotiate salary. Given the prevalence of online hiring processes, the exercise provides relevant negotiation preparation strategies in a virtual setting.
Gender and Geographic Equity in the International Association for Dental Research Awards
Authors: Lalloo R. , Borrell L.N.
Published: December 2024

Objective:

To examine the gender and geographic distribution of the International Association for Dental, Oral, and Craniofacial Research (IADR) Distinguished Scientist Awards (DSA; data: 2019–2024), group awards (data: 1982–2024), and fellowships (data: 1987–2024).

Methods:

Publicly available data were obtained from the IADR awards website. Information on gender and location of the awardees was gathered from photographs and affiliations if available or otherwise from online profiles or using Genderize, an online gender allocation platform.

Results:

Of the 99 DSA awardees in 2019 to 2024, 35% were women; 38% were from the United States, 12% were from the United Kingdom, and 11% were from Australia. Of the 35 DSA women awardees, 54% were from the United States and 11% from Finland. Of the 795 group awardees, 45% were women. Data on the location of awardees were readily available for 681 group awards; of these, 39% were from the United States and 87% were from high-income countries. Of the 113 fellowships awarded, 58% were to women. Of the 32 fellowships since 2018, 44% were for awardees from upper-middle income countries.

Conclusion:

Although women are overrepresented in the dental profession and the IADR has a global membership, women awardees remain underrepresented, and most awards are granted to researchers in high-income countries. These findings call attention to a deeper look at diversity, equity, and inclusion within the IADR.

Knowledge Transfer Statement:

Gender diversity of IADR research awards is moving in the right direction, but geographic diversity lags, with most Distinguished Scientist Awards and group awards to members in high-income countries. There is an urgent need to consider performance relative to opportunities and applications. This change in process could provide a much-needed intersectionality lens for recognizing the research performance of IADR members while increasing diversity and inclusivity.
Toward a Quantum-Inspired Framework for Modelling Legal Rules
Authors: Godfrey Nicholas
Published: December 2024

There is a growing demand for the development of computational models of legal rulesets, yet scholars acknowledge an incompatibility between the deterministic nature of current legal coding processes and the indeterminate nature of the law. Previously, legal scholars have identified conceptual links between the indeterminacy of quantum mechanics and the law, but very few have attempted to formally model the law using a framework inspired by the formalism of quantum information. I highlight similarities regarding indeterminacy as it is understood by legal and scientific scholars, motivating the construction of a quantum-inspired framework to model ambiguous legal rules. I outline how multi-qubit systems can be used to represent ambiguous legal rules formally, wherein each state of the system represents competing orthogonal interpretations of the law. I show that the amplitude corresponding to an interpretation state can represent its likelihood of validity and secondary interpretive characteristics, such as jurisprudential alignment. Using measures of classical and quantum information theory, these states can be analysed to yield information relating to forms of ambiguity, intra- and intertextuality, and inconsistencies present in a legal ruleset and interpretations. Finally, I illustrate the potential for generative artificial intelligence to assist in producing these quantum-inspired models of legal rules.
Quality of care for people with differences of sex development (DSD) in Germany
Authors: Maike Schnoor , Andreas Heidenreich , Martina Jürgensen , Ulla Döhnert , Olaf Hiort , Alexander Katalinic
Published: December 2024

Background

People with "Differences of Sex Development" (DSD) require comprehensive, specialised, and individualised medical and psychological care. This is often perceived as inadequate by those affected. Therefore, the German Federal Ministry of Health funded the project DSDCare which aimed to improve the quality of care for people with DSD over the lifespan in Germany.

Method

Indicators of structural, process, and outcome quality were defined, which are used to evaluate the quality of care. The indicators of structural quality are collected once a year from ten participating centres. Based on the "Open Source Registry System for Rare Diseases (OSSE)", a DSD-specific registry (DSDReg) was developed, in which patient-related care data are recorded in order to be able to assess the process and outcome quality. Furthermore, patient-reported outcomes are collected directly from the patients by means of questionnaires. The data are reported back to the participating centres in an annual benchmarking.

Results

Twenty-five indicators of structural quality were defined, twelve indicators of process quality and ten of outcome quality. A total of 477 patients were registered in DSDReg in the period from May 2021 till October 2022. The mean age is 16 years; the most common diagnosis groups are 46,XY DSD (34.8%), followed by 46,XX DSD (33.3%) and chromosomal DSD (27.5%). Patient numbers vary across centres from N = 10 to N = 131. Questionnaires are available from 316 (66.2%) affected individuals, including 122 from adults, 120 from children or adolescents with DSD, and 191 from parents. Preliminary results show heterogeneity between centres in both data quality and quality of care.

Conclusions

The DSDReg is well established in the DSDCare project as a quality assurance tool with continuously increasing recruitment figures. The implemented quality indicators are applicable, enable a comparison between the participating centres and will foreseeably lead to an improvement of the care of patients with DSD. A long-term continuation of the registry after the end of the initial study period is therefore indicated.
Ancient ceramics restoration method based on image processing texture stitching
Authors: Zheng Qi , Yang Hui , Yang Jianfei , Jiang Hong , Hu Weiwen , Liao Dahai
Published: December 2024

This study addresses the issue of the existence of a considerable number of ancient ceramic fragments within the gene pool of ancient ceramics in Jingdezhen, as well as the limited efficacy of manual restoration techniques. To this end, an ancient ceramic restoration method based on the stitching of ancient ceramic textures through image processing is proposed. By employing the optimal single responsiveness matrix and state transfer equation, coupled with a random sampling strategy to ascertain the precise matching points and a consistency checking mechanism to preclude erroneous matching, the optimal single responsiveness matrix is devised to meticulously transform and stitch ancient ceramic textures. The dynamic programming idea is employed to identify the optimal stitching path, thereby enhancing the quality of the stitching and facilitating the precise, seamless, and natural integration of the ancient ceramic texture. The average peak signal-to-noise ratio of the stitched image of ancient ceramics is 58.7554, and the mean square error is 0.0866, which demonstrates the efficacy of image processing technology in the restoration of ancient ceramics and facilitates the intelligent advancement of cultural protection.
Monocyte to high-density lipoprotein ratio as biomarker for cardiovascular health and cognitive function in the elderly diabetic and nondiabetic population: a case–control study
Authors: Ragheb Christina S. , Masry Manal Roshdy El , Elbasel Mohamed , Galal Mai , Rabiee Ahmed
Published: December 2024

Background

Atherosclerosis plays a crucial role in the progression of cardiovascular disease, which is still a major global health concern. Its onset and advancement are significantly influenced by inflammation, especially when it comes to the immune system’s relationship with hypercholesterolemia. Effective serum biomarkers for atherosclerosis are still elusive, despite continuous research into anti-inflammatory therapies. Both monocytes and high-density lipoprotein play important roles in inflammatory and antioxidant processes, while high-density lipoprotein cholesterol (HDL-C) provides protective benefits, and monocytes are involved in the development of atherosclerotic plaque. The monocyte to high-density lipoprotein ratio (MHR) has emerged as a promising predictor of cardiovascular events, potentially more sensitive than each one’s individual levels. Studies have investigated the relationship between MHR and cardiovascular events in a number of diseases, such as acute coronary syndrome and chronic kidney disease. This study investigates the associations between MHR, atherosclerosis, arteriosclerosis, and cognitive impairment in elderly Egyptian populations, exploring its potential as a diagnostic marker and its role in predicting cognitive decline in diabetic individuals.

Comprehending this intricate correlation is essential for developing preventive measures and targeted interventions for preventing cardiovascular disease and cognitive deterioration in the geriatrics.

Results

The study included 100 participants, 50 with type 2 diabetes and 50 nondiabetic, with a mean age of 67 years. Significant negative correlations were found between MHR and the 3MS test (r: − 0.353, p = 0.012) and (r: − 0.170, p = 0.238) and between carotid femoral PWV and the 3MS test in diabetics and in nondiabetics (r: − 0.453, p = 0.001) in both groups, suggesting a potential link between MHR and cognitive impairment.

Conclusion

This study highlights the complex relationship between monocyte to HDL-C ratio (MHR), atherosclerosis, and cognitive function in the elderly. Positive correlations were found between MHR and carotid intima-media thickness and carotid femoral PWV, suggesting a role for MHR in atherosclerosis. Notably, a negative correlation between MHR and cognitive function in diabetic individuals suggests a potential link between MHR and cognitive decline.
Ενεργειακή αναβάθμιση των αδιαφανών στοιχείων (οριζόντιων και κατακόρυφων) του εξωτερικού κελύφους
Authors: Γεωργίου Νικόλαος
Published: December 2024

Η εισβολή του 1974 και η κατάληψη του 40% του εδάφους της Κύπρου από τους Τούρκους κατακτητές, δημιούργησε ένα τεράστιο αριθμό 200,000 προσφύγων που έπρεπε άμεσα να στεγαστούν στο ελεύθερο μέρος του νησιού. Το γεγονός αυτό, οδήγησε, μέσα στις επόμενες δεκαετίες, στη δημιουργία ενός πολύ μεγάλου οικιστικού αποθέματος, το οποίο κτίστηκε γρήγορα και στόχο είχε την άμεση κάλυψη των στεγαστικών αναγκών των προσφύγων. Οι γρήγορες λύσεις, καθώς και η οικονομική ανάπτυξη που ακολούθησε τα επόμενα χρόνια, κάλυψαν μεν τις απαιτούμενες ανάγκες στέγασης, με κτιριακό απόθεμα όμως, που δεν είχε καμία πρόνοια θερμικής προστασίας των κατασκευών. Κατά συνέπεια, όλες αυτές οι κατασκευές που κτίστηκαν μεταπολεμικά και συνέχισαν να κτίζονται μέχρι και την αρχή του 21ου αιώνα, αποτελούν σήμερα, μία μεγάλη πηγή κατανάλωσης σημαντικών ποσοστών ενέργειας, για να μπορούν οι χώροι αυτοί να έχουν τις απαιτούμενες συνθήκες θερμικής άνεσης. Η έρευνα αυτή εστιάζει σε όλο αυτό το, θερμικά απροστάτευτο οικιστικό απόθεμα, το οποίο είναι ενεργό και προσπαθεί να αξιολογήσει ποιος είναι ο αποδοτικότερος τρόπος να προστατευτεί, έτσι ώστε να σταματήσει να αποτελεί εστία κατανάλωσης ενέργειας και μόλυνσης του περιβάλλοντος. Για να επιτευχθεί ο στόχος δοκιμάζονται ποικίλοι τρόποι με παθητικά συστήματα θερμικής προστασίας των κατασκευών. Λόγω της δοκιμής πολλαπλών συστημάτων, επιλέγεται όπως αξιολόγησή τους γίνει μέσω λογισμικών δυναμικής προσομοίωσης. Καθορίζεται, κατά συνέπεια, αρχικά, ένας τύπος οικιστικής μονάδας πολύ κοντά στον πολυπληθέστερο τύπο που συνθέτει αυτό το οικιστικό απόθεμα, ο οποίος θα αποτελέσει την βάση για την έρευνα και την εφαρμογή των παθητικών συστημάτων. Ο καθορισμός του τύπου αυτού αποτελεί πρωτογενή έρευνα και βασικό κομμάτι αυτής της διατριβής. Στη συνέχεια, με βάση την Κυπριακή πραγματικότητα, επιλέγονται υλικά που βρίσκονται σε αφθονία στην τοπική αγορά και δημιουργούνται συστήματα θερμικής προστασίας που στην συνέχεια αξιολογούνται στο μοντέλο της οικίας που έχει καθοριστεί από την έρευνα. Τέλος, όλα τα αποτελέσματα των πειραμάτων αξιολογούνται χωριστά, αλλά συγκρίνονται και μεταξύ τους και εξάγονται συμπεράσματα σχετικά με τον αρχικό στόχο της έρευνα, που ήταν η εύρεση του αποδοτικότερου συστήματος. Επίσης, με βάση τα αποτελέσματα, εξετάζονται και διάφορες παράμετροι που θα καταστήσουν εφικτή τη δυνατότητα εφαρμογής του συστήματος στην πράξη.
Vorwort und Impressionen
Authors: Lassau Guido
Published: December 2024

Vorwort des Kantonsarchäologen Guido Lassau und Impressionen aus dem Berichtsjahr 2023.
Tätigkeitsbericht für das Jahr 2023
Authors: Lassau Guido
Published: December 2024

Der Tätigkeitsbericht des Kantonsarchäologen bietet einen Überblick zu den wichtigsten Kennzahlen und Arbeiten in den verschiedenen Abteilungen der Archäologischen Bodenforschung im Jahr 2023.
Fundchronik: Ausgrabungen und Funde im Jahr 2023
Authors: Allemann Martin , Billo Sven , Braun Ingmar M. , Flatscher Elias , Graber Simon , Hodel Corinne , Ketzler Michael , Lißner Birgit , Martin Erik , Savary Johann , Schmidig Roman , Steiner Susan
Published: December 2024

Berichte zu den archäologischen Untersuchungen der Archäologischen Bodenforschung Basel-Stadt im Jahr 2023.
Hinter den Kulissen
Authors: Wimmer Johannes , Zurbriggen Simone , Hoffmann Annette , Bott Kati , Rissanen Hannele , Spichtig Norbert
Published: December 2024

Bei den Rettungsgrabungen in der spätkeltischen Siedlung Basel-Gasfabrik kamen im Jahr 2010 aussergewöhnliche Funde zum Vorschein. Aus Zeitgründen wurde damals das ganze Fundensemble mit dem umliegenden Erdmaterial in einem Block geborgen. Die für 2025 geplante Ausstellung des Historischen Museums Basel bildet nun den Auftakt, diesen «Schatz» konservatorisch und wissenschaftlich zu heben. Dabei stehen vorab die prachtvollen Keramikgefässe im Fokus.
In der diesjährigen Coverstory beleuchten wir exemplarisch anhand des Depotfunds von Basel-Gasfabrik Prozesse, die sonst im Verborgenen ablaufen. Konservator:innen, Analytiker und Archäolog:innen arbeiten in der ABBS Hand in Hand, um die Objekte aus dieser rituellen Niederlegung sachgerecht zu konservieren und zu erforschen, bevor sie einem breiten Publikum präsentiert werden.
Hasta Bilgilerinin Yönetimi ve Gizliliğin Korunması
Authors: Aygın Dilek , Gül Aysel
Published: December 2024

Günümüzde bilim ve teknolojide yaşanan gelişmeler, hastaların kaliteli tedavi ve bakım alma istekleri ve bunları belirleme talepleri, kişisel verilere erişimi kolaylaştırmış olup bilgilerin korunması ve saklanması gereksinimini de beraberinde getirmiştir. Güvenilir bakımın temeli olan hasta mahremiyetinin korunması, bireysel otonominin bir gerekliliğidir. Bu noktada son derece hassas olan hasta bilgilerinin gizliliği ve bu bilgilerin aktarılması önemli bir parametredir. Özellikle sağlık sisteminde ileri teknolojilerin kullanılması, sağlık bilgilerine anında erişimi ve bilgi alışverişini kolaylaştırmakta, bakımın kalitesini arttırmakta ancak gizlilik ve mahremiyet ihlallerine ilişkin etik kaygılar da doğurmaktadır. Doğru bilginin yayılması, sağlık profesyoneli-hasta ilişkisinin etik ve pragmatik ilkeler çerçevesinde iyileştirilmesi ve tıbbi uygulamaların geliştirilmesi gibi birçok faydası bulunan bu sistemlerin gizlilik ve mahremiyet ihlallerine ilişkin olası risk ve engellere sahip oldukları açıktır. Bu konu ile ilgili yeterli sayıda çalışma olmadığı görülmektedir. Yapılan çalışmalarda, birbirinden farklı ileri sağlık bilgi teknolojilerinin ayrı ayrı incelendiği, yöntemler arasında değerlendirme yapılmasına olanak tanıyacak bir ortamın oluşturulmadığı görülmektedir. Buradan yola çıkarak oldukça önemli olan hasta hakları, hasta bilgilerinin gizliliği ve bu bilgilerin aktarılması konusunda yapılmış çalışmalara değinilerek farkındalığı arttırmak ve bu konuda uygun politikaların geliştirilmesine referans oluşturmak amacıyla bu derleme makale kaleme alınmıştır.
Strategic management in professional education organizations
Authors: Ryzhikov Sergey , Patrahina Tat'yana
Published: December 2024

The textbook outlines the issues of strategic management of a professional educational organization, suggests methods for assessing its external and internal environment, and discusses current problems of knowledge and competence management. The issues of evaluating the effectiveness of strategic management are comprehensively covered.
It is intended for students, students of the postgraduate education system, managers, teachers and employees of professional education organizations interested in strategic management issues, for advanced training and retraining of educational workers.
Administrative activities of the internal affairs bodies. The special part
Authors: Mironov Rinat
Published: December 2024

The textbook has been prepared on the basis of current Russian legislation, which is important for the organization and implementation of administrative activities of internal affairs bodies (ATS), ensuring the protection of public order and public safety in order to protect the rights, freedoms and legitimate interests of citizens, organizations and associations, and consists of two parts: Common and Special.
The main directions, goals and objectives of the special (special) administrative activities of the Department of Internal Affairs, the powers and competencies of police services and units to ensure law and order in the territory of the Russian Federation are disclosed.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For students, cadets and trainees of higher educational institutions studying in the field and specialty "Jurisprudence", as well as for teachers and practitioners.
Historical local lore of the Crimea
Authors: Ternovaya Lyudmila
Published: December 2024

In the textbook, as part of the study of the problems of historical local lore based on the materials of the Crimea, socially and politically significant issues of the development of this geopolitical and historical and cultural space are comprehended. It is shown how complex ethnic, social, economic, spiritual and moral processes merged on it, resulting in a unique world capable of simultaneously absorbing the experience and images of other regions and developing its own meanings that influence not only the socio-cultural and economic development of Russia, but also its geopolitical strategy.
It is intended for teachers of the course "Historical local lore of the Crimea", as well as for students studying in the fields of history (03/46.01), cultural studies (03/51.01), social work (03/39/02) and tourism (03/43/02). Due to the relevance and attractiveness of the issues raised in the textbook, which relate to the fields of history and ethnography, culture and art, economics and geopolitics, sociology and ecology, the materials presented in the book may be of interest to a wide range of readers.
Sociology of Management in a Transitive Society: Theory and Empirical Research Experience
Authors: Gostenina Valentina
Published: December 2024

The textbook examines the theoretical aspects and empirical patterns of management in a transitive society. The tasks of studying the course, a workshop for self-checking knowledge, skills and abilities, topics and content of the lecture material are presented.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For students in the fields of "Sociology of Management", "Sociological diagnostics of human potential in a digital society", "Psychology of management", "Digital Economy and regional management", "Management of technosphere security of territories and economic facilities", as well as for teachers, employees of management services, civil servants and graduate students.
The History of the Far East
Authors: Fedirko Oksana , Dudarenok Svetlana , Krupyanko Aleksandr , Isaev Aleksandr , Savchuk Anna , Krupa Tat'yana , Druzyaka Andrey , Din Yuliya
Published: December 2024

The textbook covers the history of the Russian Far East from ancient times to the present. The key problems of the history of the Far East in the context of Russian history are formulated.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For students and university professors, school teachers and anyone interested in the history of the Russian Far East.
Countering crimes in the field of information technology
Authors: Kalinichenko Igor' , Andreev Aleksey , Galiev Denis , Gonchar Vladimir , Gorach Nikolay , Dzhafarova Naylya , Zaharov Dmitriy , Ziborov Oleg , Klishina Natal'ya , Lyuban Vladislav , Molchanova Tat'yana , Puzyreva Yuliya , Ryadovskiy Igor' , Staschenko Stanislav , Tisen Ol'ga , Himicheva Ol'ga , Chekunov Igor' , Sharov Aleksandr
Published: December 2024

The textbook discusses the main issues related to the specifics of countering crimes in the field of information technology.
An integrated approach is used to train specialists for the internal affairs bodies of the Russian Federation engaged in countering crimes in this area. Administrative-legal,
criminal-legal, criminal-procedural, criminalistic, criminological, operational-investigative, organizational-legal and organizational-technical aspects of the activities of law enforcement officers to counter illegal activities in the field of information technology are reflected.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For teachers, cadets, trainees and students of educational institutions of legal and technical profile, as well as for law enforcement officials specializing in countering illegal activities in the field of information technology.
The specter of Asperger’s syndrome in Parent–Infant Psychotherapy. A case report.
Authors: Kałwa Agnieszka
Published: December 2024

Psychoanalityczna psychoterapia rodzic–niemowlę (Parent–Infant Psychotherapy PIP) jest w Polsce oferowana od niedawna. Jej podstawę stanowią teorie psychoanalityczne, wzbogacone o dane ze współczesnych badań naukowych. Artykuł stanowi psychodynamiczną konceptualizację procesu psychoterapii PIP. Istotną rolę odgrywają w niej hipotezy terapeutki dotyczące świadomych i nieświadomych elementów składowych relacji między rodzicami i niemowlęciem oraz występujących w niej problemów. Na ich podstawie formułowane są cele terapeutyczne oraz dobierane metody, jakimi można się posłużyć w ramach interwencji terapeutycznej. Hipotezy terapeutyczne obejmują przeciwprzeniesienie, obserwacje i interpretacje terapeutki. W artykule opisano proces psychoterapii PIP niemowlęcia i jego rodziców, która objęła 40 sesji. Rozpoczęła się, gdy dziecko miało 5 tygodni, a zakończyła się, gdy miało 17 miesięcy. Od początku ważny temat stanowiła kwestia diagnozy zespołu Aspergera. Odgrywała ona już istotną rolę w jego życiu w momencie rozpoczęcia terapii, choć zdaniem rodziców mogła zostać postawiona dziecku w przyszłości. Niniejsza praca opisuje, co stało się z widmem zespołu Aspergera w opisanej wyżej rodzinie w trakcie procesu terapii PIP.
Quo Vadis Climate Transition Risk? A Literature Review and Recommendations
Authors: Oguntuase Oluwaseun J. , Ajibare Adedayo O.
Published: December 2024

This paper examines the academic research on climate transition risk. Theobjective of this study is to provide descriptive characteristics of research trends inthe field of climate transition risk and make recommendations based on major bibliometricdata such as authors, journals, citation figures, methodology, geographicalfocus and author’s location. The systematic literature review methodology was usedto obtain information on publications and intellectual structure related to climatetransition risk from the Scopus bibliographic database until November 2023. A searchstrategy was developed to screen the title for eligibility, using the abstract and full textwhere needed. The review showed that annual evolution has increased significantlyin recent years. Findings revealed a marked European and Chinese dominance with little contribution from Global South in this research field with limited contributionsfrom Global South in terms of focus and authors and organizations contributions. Thepredominant data source is data-set indices, with limited methodological diversity inclimate transition risk research. Findings also showed that authors from universities,research institutes and central banks are contributing to climate transition risk literature. The main themes in climate transition risk research are banking, climate policy,stock market, and asset price and performance. The impacts of climate change on interconnectedness,systemic risk and financial stability were widely covered in overlappingpublications.
Evaluating the Efficacy and Safety of Baricitinib in Reducing COVID-19 Mortality: A Comprehensive Review of Clinical Evidence and Pharmacological Strategies
Authors: Kwaśniewska Paulina Klaudia , Graczyk Patryk , Wilewska Anna , Borowiec Kinga , Borowiec Agnieszka , Biernikiewicz Julia , Alabrudziński Konstanty , Biernikiewicz Milena , Pomirski Bartosz , Pomirska Agata
Published: December 2024

Introduction: COVID-19 manifests with symptoms ranging from mild to severe, including respiratory and cardiovascular complications. Severe cases are often marked by a cytokine storm, causing pulmonary damage and multi-organ dysfunction. Current treatments lack a specific antiviral, though several pharmacological options, including immunomodulatory and antiviral drugs, are under investigation.
Purpose: The purpose of this article is to provide an evaluation of the efficacy and safety of baricitinib, a JAK inhibitor, combined with standard care for hospitalized adults with COVID-19. By reviewing recent literature, it aims to assess baricitinib's effectiveness in improving patient outcomes.
Material and methods: A systematic review of clinical trials and case studies was conducted to analyze baricitinib’s impact on COVID-19 mortality. Data includes treatment-emergent adverse events and patient outcomes in moderate to severe cases.
Discussion: Baricitinib has demonstrated potential in managing hyperinflammation in severe COVID-19 by inhibiting multiple proinflammatory cytokines and enhancing immune response. Clinical trials show that baricitinib, particularly in combination with corticosteroids, reduces mortality and serious infections compared to standard care alone. Due to potential adverse events, continuous monitoring of hematological and lipid levels is essential. These findings highlight baricitinib's dual role as an immunomodulatory and antiviral agent, suggesting its importance in treating severe COVID-19. Future research should focus on optimizing treatment regimens and further exploring the long-term implications of baricitinib therapy.
Scripti versus manu Philippi… or the Album Amicorum with an Entry by Philipp Melanchthon from the Collection of the University of Warsaw Library
Authors: Milewska-Kozłowska Joanna
Published: December 2024

Early printed books are valuable artefacts not only because of their content but also for the annotations inscribed on their pages. The album of friends presented in the paper is a Wittenberg edition of the psalms in Martin Luther’s translation from 1551, with annotations by the praeceptor Germaniae Philipp Melanchthon and other well-known reformers of the sixteenth century, as well as laypersons affiliated with the court of the dukes of Pomerania. After discussing individual entries, we attempt to identify the owners of the book and outline the circumstances under which it found its way into the collection of the University of Warsaw Library.
Mental Health Implications of Acne Vulgaris
Authors: Sieradocha Kamila
Published: December 2024

Acne vulgaris, a prevalent chronic inflammatory skin condition, affects approximately 9.4% of the global population, with implications that extend beyond physical appearance to significantly impact mental health. While acne primarily manifests through visible skin lesions, such as comedones, papules, and pustules, the condition’s psychological toll can be profound. Many individuals with acne experience elevated levels of anxiety, depression, and reduced self-esteem, especially adolescents, for whom acne can disrupt self-identity formation. These mental health challenges are often exacerbated by the social stigma associated with visible skin conditions, leading to issues like social withdrawal, body image concerns, and, in severe cases, even suicidal thoughts.
Effectively managing acne requires a holistic approach that addresses both physical symptoms and psychological well-being. Dermatological treatments, including topical retinoids, benzoyl peroxide, and oral isotretinoin, are commonly used to control acne symptoms. Dietary modifications, such as reducing high-glycemic foods and dairy, and the use of probiotics, have shown promise as supportive measures. However, addressing the psychological component is equally critical; integrating psychological interventions, such as counseling, cognitive-behavioral therapy, and patient education, can help alleviate the mental strain associated with acne, improve adherence to treatment, and enhance quality of life.
Further research is essential to explore the long-term benefits of combined dermatological and psychological treatments and to develop personalized approaches that consider individual psychological profiles. A comprehensive treatment model that incorporates both physical and mental health support offers the potential for improved outcomes, fostering both dermatological recovery and mental resilience in individuals affected by acne vulgaris.
Therapeutic Potential of Silicon Supplementation in Age-Related Diseases: A Comprehensive Review
Authors: Koczkodaj Maria , Kotowicz Michał , Mormul Agata
Published: December 2024

Silicon, the second most abundant element in nature, plays a crucial role in human health. Despite its understated presence, silicon's multifaceted contributions to various physiological processes make it a promising option for therapeutic intervention. Through a comprehensive analysis of recent scientific literature, this review explores the impact of silicon supplementation on bone health, cardiovascular function, metabolic regulation, and neuroprotection. Review methods involved the analysis of scientific publications found in databases such as PubMed and scientific journals, including meta-analyses, randomized trials, and systematic reviews, concerning the scope of medical and nutritional problems, excluding case reports.
Key findings suggest that silicon supplementation may positively influence bone mineral density, bone regeneration, and collagen synthesis, offering potential benefits for individuals at risk of osteoporosis and musculoskeletal disorders. Furthermore, evidence highlights silicon's role in regulating cardiovascular health, indicating its potential to mitigate atherosclerosis risk and improve lipid profiles, thereby offering promise in managing conditions such as diabetes and dyslipidemia. Additionally, emerging research underscores silicon's neuroprotective properties, hinting at its potential in combating neurodegenerative diseases like Alzheimer's. This review emphasizes the promising prospect of silicon supplementation as a complementary strategy for enhancing overall health and addressing age-related diseases.
Sauna and health
Authors: Łagowski Ryszard , Kosęda Julia , Fordymacki Jacek
Published: December 2024

Sauna use, practiced for thousands of years, has its roots in Finnish culture, where it was considered an essential part of health and hygiene. In recent years, a growing body of scientific research has confirmed the numerous health benefits associated with regular sauna use. This research review focuses on the effects of sauna sessions on the body's health, with particular emphasis on the cardiovascular system, blood pressure, respiratory system and urinary system. Analyses show that regular sauna use contributes to lowering the risk of cardiovascular disease by reducing blood pressure and improving the lipid profile. In addition, sauna has a beneficial effect on lung function, reducing the risk of diseases such as chronic obstructive pulmonary disease and pneumonia. It is also worth noting that sauna baths are safe for patients with kidney disease, as confirmed by research results. These indications underscore the importance of regular sauna sessions as a form of health support, helping to improve quality of life and long-term well-being.
Recent Advances in Bacopa Monnieri Research: Neuroprotective Effects and Cognitive Decline Mitigation in Neurodegenerative Diseases with a Focus on Alzheimer’s and Parkinson’s Diseases
Authors: Bychowski Mateusz , Kwaśna Julia , Górski Mateusz , Załęska Adrianna , Kaźmierczyk Izabela , Lenart Kacper , Homza Michał , Zakrzewska Natalia , Bednarek Szymon , Kulicka Joanna
Published: December 2024

Background: The global rise in neurodegenerative diseases, including Alzheimer’s and Parkinson’s, has increased interest in natural nootropics such as Bacopa Monnieri. Known for its neuroprotective properties, Bacopa Monnieri has a long history in traditional medicine. This review examines its role in cognitive enhancement, focusing on its effects in neurodegenerative diseases.
Methods: Relevant studies published after 2020 were analyzed to assess Bacopa Monnieri’s impact on memory, concentration, and neuroprotection, particularly in Alzheimer’s and Parkinson’s. The review explores mechanisms such as neurotransmitter modulation, reduced neuroinflammation, and enhanced synaptic plasticity.
Results: Bacopa Monnieri exhibits neuroprotective effects beneficial for cognitive health and neurodegenerative diseases. It has antioxidant and anti-inflammatory properties, promotes neurogenesis, and increases Brain-Derived Neurotrophic Factor (BDNF). In Alzheimer’s models, it improved cognitive function, reduced amyloid plaques, and prevented Tau aggregation. In Parkinson’s, it enhanced dopaminergic function and reduced neuroinflammation. Despite promising findings, more robust clinical trials are required to confirm its efficacy.
Conclusion: Bacopa Monnieri demonstrates potential in neuroprotection and cognitive enhancement, particularly in Alzheimer’s and Parkinson’s. It improves synaptic health and reduces oxidative stress and neuroinflammation. However, larger, high-quality trials are needed to fully establish its therapeutic role in neurodegenerative diseases.