bluuebunny/crossref_metadata_2025 huggingface dataset:
Los retratistas de la corte de Saboya en el siglo XVI y sus relaciones con España
Authors: Pérez de Tudela Almudena
Published: March 2024

Los estrechos vinculos familiares entre Emanuel Filiberto I de Saboya y Felipe II propiciaron que intercambiaran retratos familiares desde que separaron en 1551. El italiano envió a su pintor Giorgio Solario a la Península Ibérica en una campaña entre 1578 y 1580 para retratar a las familias reales portuguesa y española. Paralelamente otros pintores, como Alessandro Ardente viajaba a la vecina corte de Parma para retratar al sobrino de Felipe II, Alejandro Farnesio y a toda su familia. Sin embargo, el pintor más destacado fue Jan Kraeck, italianizado Giovanni Caracca, quien acompañó a Carlo Emanuele de Saboya a Zaragoza en 1585 con motivo de su matrimono con la infanta Catalina Micaela. Un segundo viaje a España para retratar a la familia real española tuvo lugar entre 1591 y 1592.
Ensalzamiento monárquico y nobiliario: el programa decorativo del palacio de Cusano en Milán
Authors: Martínez Leiva Gloria
Published: March 2024

Tras el matrimonio de Carlos Homodei con Leonor de Moura en 1678 este pasó a ser el nuevo marqués de Castel Rodrigo. Nombrado General de la Caballería extranjera en Milán en 1680, el IV marqués de Castel Rodrigo ordenó un nuevo programa iconográfico en su palacio de Cusano, en los alrededores de Milán, para dejar constancia tanto de su pertenencia a los Castel Rodrigo como de su labor como representante de la Monarquía de los Austrias. Las decoraciones que se llevaron a cabo pretendían parangonar las empresas arquitectónicas de los Castel Rodrigo y los Homodei con las llevadas a cabo por los Austrias. De ese modo, se creaba un juego muy propio de la época, mostrando al rey como espejo y a la nobleza como reflejo de su gusto.
Bernaert de Rijckere, un artista a la sombra de Frans Floris. Sobre los tronies femeninos del museo de Bellas Artes de Bilbao y del museo Nacional de Varsovia (Polonia)
Authors: Diéguez Rodríguez Ana
Published: March 2024

Una pintura de la segunda mitad del siglo XVI representando un busto femenino del museo de Bellas Artes de Bilbao, ha sido durante largo tiempo tenida por obra florentina. No es hasta comienzos del siglo XXI en que se ha relacionado con la escuela flamenca, y en particular con el taller de Frans Floris. En este trabajo, sin embargo, se relaciona con el de otro coetáneo, menos conocido, pero con una producción importante en su momento, Bernaert de Rijckere. Es la serie de cinco tronies conservada en el museo nacional de Varsovia, los que ayudan en esta identificación y permiten plantearse otra iconografía para estas cabezas femeninas en relación con las Sibilas.
Sobre Benito Sánchez Galindo y el Maestro de la tabla de San Benito de Montserrat: pinturas del retablo de la capilla de Talavera (Catedral Vieja de Salamanca)
Authors: González Martínez Eloy
Published: March 2024

En este artículo se estudian las pinturas que forman parte del retablo renacentista que alberga la capilla de San Salvador o Talavera, en la Catedral Vieja de Salamanca. Aunque ya se habían hecho distintas propuestas sobre su autoría, las nuevas aportaciones al estudio de la pintura española del siglo XVI permiten centrar de forma más precisa la cuestión. De esta forma, el presente estudio las atribuye a un pintor anónimo cuyo estilo viene definido por las obras publicadas por la Carmelo Solís e Isabel Mateo a nombre de Benito Sánchez Galindo. Sin embargo, investigaciones posteriores obligan a deslindar las pinturas de la mano de este maestro, por lo que en este trabajo se le acuña el nombre convencional del “Maestro de la tabla de San Benito de Montserrat”, mientras no se pueda identificar a través de una evidencia documental. Asimismo, se pone en relación con las pinturas del retablo de la iglesia de San Pedro en la localidad extremeña de Garrovillas de Alconétar.
Aspects of the European Union’s climate policy in the context of the opportunities offered by the building sector – innovation in action
Authors: Wojtas Magdalena
Published: March 2024

The European Commission wants Europe to become climate-neutral by 2050. 28 November 2018. The Commission has set out a long-term strategic vision for a prosperous, modern, competitive and, above all, climate-neutral economy by 2050, showing how Europe can lead the way in achieving this goal by investing in realistic technologies, empowering citizens and adapting policies in such areas like industrial policy, finance and research. In this transition process, social justice must also be guaranteed. The Commission’s vision for a climate-neutral future, following the suggestions of the European Parliament and the European Council, covers almost all EU policies and is in line with the Paris Agreement objective of keeping the temperature increase well below 2°C and trying to bring it down to 1.5°C. The Commission adopted its strategic vision on 28 November 2018 in advance of the UN Climate Summit (COP24), which took place from 2 to 14 December in Katowice. Clean technologies are opening up new opportunities for industry and investors, even if capital markets are slower to adapt to the climate economy. Renewable technologies such as solar, hydro or wind energy are expected to enable the EU to reduce its greenhouse gas emissions by up to 90% by 20502.
РАСПРЕДЕЛЕНИЕ ТЯЖЕЛЫХ МЕТАЛЛОВ (ТМ) В ДЕПОНИРУЮЩИХ СРЕДАХ В ЗОНЕ ВЛИЯНИЯ АВТОМАГИСТРАЛЕЙ СВАО И ЮЗАО ГОРОДА МОСКВЫ
Authors: Еременко К.В. , Зубкова В.М. , Пугачева Т.Г. , Арсланбекова Ф.Ф.
Published: March 2024

В статье приведена оценка загрязнения снежного покрова, почв и листьев древесных растений тяжелыми металлами (ТМ) на участках, расположенных вдоль автомагистралей СВАО и ЮЗАО города Москвы, указывающая на умеренный и умеренно-опасный уровни загрязнения снега и почвы при наибольшем долевом участии железа, стронция, бария, цинка и марганца.
ВОЗМОЖНОСТИ ПРОДУКТОВ ИЗ МЕСТНОГО СЫРЬЯ В СОХРАНЕНИИ ЗДОРОВЬЯ НАСЕЛЕНИЯ АРКТИКИ
Authors: Олесова Л.Д. , Миронова Г.Е.
Published: March 2024

Профилактика метаболического дисбаланса с последующим развитием алиментарно-зависимых заболеваний у жителей Арктики требует поиска путей коррекции недостаточности основных веществ, макро- и микронутриентов. Рекомендации диетологов в первую очередь касаются учета в рационе национальных особенностей и сохранения этнического питания: увеличение потребления традиционных продуктов - рыбы, мяса, молочных продуктов, ягод, произрастающих в этих климатических зонах. Во-вторых, создание новых функциональных продуктов, обогащенных биологически активными соединениями из местного растительного и животного сырья. В-третьих, необходима широкая пропаганда здорового образа жизни, в том числе обеспечение информированности населения о здоровом питании и о вреде, наносимой высоким потреблением хлебобулочных, кондитерских изделий, сахара, сдобы, сладостей и газированных напитков. Эффективность коррекции рациона питания северных популяций возможна в условиях повышения качества жизни.
РЕКРЕАЦИОННОЕ ИСПОЛЬЗОВАНИЕ МАЛЫХ РЕК ГОРОДОВ
Authors: Колошин Н.В. , Топорина В.А.
Published: March 2024

В связи с бурным демографическим ростом в Московском регионе, у населения возникает проблема недостатка рекреационных ресурсов. С одной стороны, в самой столице находится множество парков, заказников и даже несколько ботанических садов, однако для эти территории распределены неравномерно. С другой стороны, развитие инфраструктуры и транспорта улучшили доступность ко многим территориям, поэтому их ценность из-за растущей рекреационной нагрузки снижается. В связи с этим цель данной работы - выявить наиболее подходящие водные объекты, находящиеся на территории Московского региона, прибрежная часть которых может использоваться для выполнения рекреационных функций. Были проанализированы основные проблемы, такие как загрязнение воды, нарушение экосистемы рек, негативное воздействие рекреационной деятельности на окружающую среду.
РАЗРАБОТКА ДОРОЖНЫХ КАРТ В ТЕХНИЧЕСКИХ ВУЗАХ С ИСПОЛЬЗОВАНИЕМ ИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ И ЦИФРОВЫХ РЕШЕНИЙ
Authors: Воробьев К.А. , Чекушина Т.В.
Published: March 2024

В статье исследуется значимость и применение дорожных карт в контексте образования в технических вузах. Дорожные карты - это наглядные и структурированные планы учебного курса или проекта, в которых определены цели, задачи, ключевые этапы и учебные ресурсы для достижения успеха. В статье представлен обзор существующих методик разработки и использования дорожных карт в техническом образовании, а также приведены примеры практического применения. Авторы рассматривают роль дорожных карт в повышении эффективности самоорганизации студентов, создании системного подхода к обучению и развитию навыков профессиональной работы. Статья также освещает влияние дорожных карт на процесс планирования и достижения карьерных целей студентов технических вузов. Исследование заключается в том, что использование дорожных карт в техническом образовании играет ключевую роль в формировании у студентов навыков самостоятельности, организации работы и преуспевания в будущей работе.
Implementation and Analysis of Software for Control and Administration of Expenses in Machinery
Authors:   Student PhD in Projects, American University of Europe, UNADE Cancún, Quintana Roo, México, Zamudio Carlos Enrique López , Fonseca Fabiola Colmenero ,   Architect, Training Department, American University of Europe, UNADE Cancún, Quintana Roo, México
Published: March 2024

In the last three years, the use of technological and online resources has increased, going beyond borders. The problem is focused on the insufficiency of control of expenses to manage, therefore, control is lost and as a result of this the need to have a new tool is created; without this, it is believed unnecessary to be able to carry it in an orderly and correct manner. This article is based on the experience and empirical work of the construction specifically in the ERPs or software to keep an effective control, considering that the machinery is a generator of income and with it to put emphasis to obtain good results. A qualitative and quantitative analysis was carried out, in companies that use a similar type of software, a comparison is made in two programs, identifying in the COMPANY-A program the lack of reports unlike CharLow MACHINERY, therefore, the need for Create a new software that includes all the previous reports and therefore a relationship is established from the data analysis of the new software. The results show that the creation of this type of software solves the problems of administration and control of a company as part of a monitoring in a first phase to obtain the positioning of the user and team and in a second phase the version 2.0 working in customer satisfaction the users.
Why the Basic Axioms of Risk Assessment Can Be Problematic to Identify Risk? – The Development of the VUCA Meter
Authors:   Assistant Professor, Reykjavik University, Iceland, Fridgeirsson Thordur Vikingur , Ingason Helgi Thor ,   Professor at Reykjavik University Reykjavík, Capital Region, Iceland
Published: March 2024

The VUCA world is the epitome of the challenges linked with some of the undercurrents currently shaping businesses in the projectified society. The terms Volatility, Uncertainty, Complexity and Ambiguity (VUCA) are used as descriptive for the continuous flux project managers and project planners are forced to keep at bay. In this article, the authors present an idea to connect the VUCA concept as a risk identification platform to access, identify and isolate low-probability but high-impact events often called black swans or fat tail events. It is argued that the assumptions of conventional risk assessment in the domain of project management can lead to skewed general outcomes due to limitations of the intellect to assess probability. The outline of the VUCA meter is drafted and argued that the meter can augment the conventional risk assessment approach.
Artificial Intelligence in Marketing: A Theoretical Overview from a Developing Economy
Authors:   School of Information Office Technology and Management, Department of Business Administration and Management, Tatari Ali Polytechnic, Bauchi, Nigeria, Ibrahim Muhammed Kabir , Muhammed Abdullahi ,   School of Information Office Technology and Management, Department of Business Administration and Management, Tatari Ali Polytechnic, Bauchi, Nigeria, Ahmed Sani ,   AD Rufa’I College of Education, Legal and General Studies, Misua, Nigeria
Published: March 2024

Marketing offers a lot of potential for Artificial Intelligence (AI). It assists in expanding information and data sources, enhancing software’s data management abilities, and developing complex and sophisticated algorithms. The interactions between businesses and customers are altering as a result of AI. The way this technology is used depends a lot on the sort of business and website being used. Marketers are now better able to concentrate on the customer and immediately address their demands. Because AI gathers and generates data through its algorithms, businesses can swiftly decide what content to target customers with and which channel to use when. When AI is used to personalise user experiences, users are more comfortable and likely to make purchases. AI techniques can also be used to examine the effectiveness of rival efforts and uncover the expectations of their target audiences. Computers can now analyse and interpret data without explicit programming thanks to machine learning (ML), a subset of artificial intelligence. Furthermore, ML helps people solve issues effectively. As more data is fed into the algorithm, it learns and gets better at performing and being accurate. This paper theoretically highlighted on the essentiality AI in marketing in developing economies like Nigeria
Improvements in Clinical Laboratory Techniques, Technologies, and Practices with a Focus on the Equipment and Personnel: A Consolidated Review
Authors:   Center of Clinical Laboratory Medicine, Zhongda Hospital, Medical School of Southeast University, People’s Republic of China, M Zhou , Y Yao ,   Center of Clinical Laboratory Medicine, Zhongda Hospital, Medical School of Southeast University, People’s Republic of China, G Wu ,   Center of Clinical Laboratory Medicine, Zhongda Hospital, Medical School of Southeast University, People’s Republic of China
Published: March 2024

Background and Aims: In recent years, exquisite diagnostic techniques are stringent demands in Medical Laboratory Science (MLS). The reviews discuss ways to improve clinical laboratory techniques under the current level of medical care in China. Materials and Methods: With a focus on China’s current situation and development direction of clinical detection technology, journal literature was reviewed; reforms in the educational concepts were studied. Herein, reforms in the management practices of clinical medical testing departments as well as the development and production status of medical testing instruments are discussed. Results: Medical schools should change the educational concept from the traditional “indoctrination” teaching method to a diversified teaching method. Hospitals should strengthen the daily management of laboratories and improve professional of the laboratory personnel. The government should strategically set up regional inspection centers to provide medical inspection services for small hospitals at the township and community levels. Manufacturers should be encouraged to develop and produce advanced instruments to continuously improve the efficiency and accuracy of the instrumental test results. Conclusions: Diversity teaching method in hight medical schools, daily management improvement of laboratories and government supporting will cultivate excellent medical laboratory personnel, improve clinical laboratory techniques.
Rituximab for Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Authors:   Department of Neurology, Albany Medical Center, United States, Pak Stella , Abdelhak Tamer ,   Department of Neurology, Albany Medical Center, United States, Varelas Panayiotis ,   Department of Neurology, Albany Medical Center, United States
Published: March 2024

Anti-N-Methyl-D-Aspartate (NMDA) receptor encephalitis is a severe, but potentially reversible autoimmune encephalitis, dominantly affecting children and young adult women [1]. Approximately 60% of patients with NMDA encephalitis have tumors containing nervous tissue, such as ovarian teratoma [2].
Exploring the New Targets for Candida Vaginiitis
Authors:   Department of Pharmacy, Krishna University College of Pharmacy and Research, India, Dasari Santhi Krupa , B Janakiram ,   Department of Microbiology, NRI Medical Hospital, India, Jeevigunta Naveena Lavanya Latha ,   Department of Biosciences and Biotechnology, Krishna University, India
Published: March 2024

A vaginal yeast infection, also known as vaginal candidiasis, genital candidiasis, or Vulvovaginal Candidiasis (VVC), is an infection involving a type of fungus, or yeast. The fungus most commonly associated with vaginal yeast infection is called Candida albicans, which account for up to 92% of all cases, with the remainder due to other species of Candida. These fungi can be found all over the body and are normally present in warm and moist areas of the body. Studies have shown that up to 20%-50% of all women normally carry yeast in the vagina without the presence of symptoms. When C albicans in the vagina multiplies to the point of infection, this infection can cause vaginal inflammation, irritation, odor, discharge, and itching.
Candidemia - Species Distribution and Antifungal Resistance Patterns in Two Tertiary Care Centers in South India
Authors:   Department of Clinical Microbiology, Yashoda Hospital Secunderabad, India, P Nimmala , S Prakasham ,   Department of Clinical Microbiology, Yashoda Hospital Secunderabad, India, M Anand ,   Department of Clinical Microbiology, Yashoda Hospital Secunderabad, India
Published: March 2024

Background: Bloodstream infections due to Candida species are a significant cause of morbidity and mortality in hospitalized patients worldwide. Epidemiology of Candidemia is dynamic with reports of non-albicans Candida species on a steady increase and the emergence of C.auris reported from many centers in India. This study was undertaken to analyze species distribution and antifungal susceptibility of Candida bloodstream infections in two tertiary care centers in Telangana, South India. Material and Methods: In a retrospective analysis, Candida isolates from blood cultures of patients with suspected bloodstream infection over five years (2017-2021) were identified and tested for antifungal susceptibility by Vitek 2 Compact (Biomerieux, France). Results: A total of 85,603 blood cultures were processed from two centers from January 2017 to December 2021. Among these, 270 (0.31%) Candida species were isolated. Of the total Candida isolates, C. tropicalis (49.2%) was the most common isolate, followed by C. albicans 55 (20.3%), C. glabrata 35 (12.9%), C. parapsilosis 25 (9.2%), C. auris (5.5%), C. guilliermondii (1.4%) and C. krusei (1.1%). We have tested six antifungals and of the total isolates, resistance to fluconazole was highest (11.9%) followed by amphotericin B (7.0%), caspofungin (2.9%), voriconazole (2.3%), flucytosine (1.8%) and micafungin (0.7%). C.auris isolates were found to be resistant to two or three classes of antifungals tested and 13.3% were pandrug -resistant. Conclusion: C.tropicalis was the most common isolate and each Candida species showed varied antifungal resistance rates. We emphasize the need for the identification of Candida species and antifungal susceptibility for every invasive isolate to tailor targeted preventive and therapeutic antifungal strategies in line with current evidence and guidelines.
Mechanisms of Antimicrobial Resistance and Its Diagnostic Techniques in Nontyphoidal Salmonella Infections
Authors:   Animal Health Institute (AHI), PO Box: 04, Sebeta, Ethiopia, EM Hambisa , AA Umer ,   Animal Health Institute (AHI), PO Box: 04, Sebeta, Ethiopia
Published: March 2024

Antimicrobial Resistance (AMR) is the decreased sensitivity of microbes to drugs that are capable of causing cell death or inhibition of growth. It is one of the key issues linked with foodborne infections caused by various resistant pathogenic microorganisms. Nontyphoidal Salmonella (NTS) is one of the leading causes of food-borne infections in which its serotypes are usually zoonotic. The source of this resistance is classified as natural and acquired and the mechanism of AMR emergence in NTS can also be divided into two broad categories: biochemical and genetic mechanisms. The biochemical mechanisms are enzymatic inactivation, antimicrobial permeability reduction, active efflux pumps, and others; while the genetics mechanisms include mutation and horizontal and vertical resistant gene transfer. The techniques of AMR diagnosis are conducted by conventional and non-conventional methods. The utilization of antimicrobials for growth promotion, prophylaxis and its misuse in humans or animals, and contamination of the environment are some of the factors that attribute to AMR development. NTS infection is common throughout the world including Ethiopia and developed resistance to different antimicrobials, and the mechanism of AMR development and its diagnosis is not common in the developing countries including our country. The mechanisms by which NTS develop resistance to antimicrobials should be known very well and its dissemination to human, animals, and the environment could be managed, and methods for the diagnosis of AMR in NTS species should be available for the identification of resistant antimicrobials to give proper treatments and other measures. Additionally, proper policies and regulation systems on antimicrobial use and its distribution should be developed and implemented properly.
Implications of Threat in Swot Analysis in Setting up a New Medical Research Center in Nigeria
Authors:   School of Public health, The University of America, Curacao, Department of Medical Laboratory Science, College of Medicine, Enugu State University of Science and Technology, Enugu State Nigeria, Igwe Matthew Chibunna
Published: March 2024

Conducting a thorough SWOT analysis that includes identifying threats is essential for setting up a new medical research center in Nigeria. Recognizing threats and understanding their implications allows for proactive planning, resource allocation, risk management, stakeholder engagement, and strategic decision-making, all of which contribute to the overall success and sustainability of the research center. Developing contingency plans to minimize the impact of threats in setting up a new research center in Nigeria is crucial for ensuring the center’s stability and success. And also adapting the threat matrix and contingency plans can help minimize the impact of threats when setting up a new research center in Nigeria. Involving security experts, local authorities, and consulting with local stakeholders can provide valuable insights and improve the accuracy of the threat matrix. It is important to note that the specific threats and their categories may vary depending on the research center’s location, sector, and other contextual factors. Adhering to international best practices, leveraging local knowledge and expertise, and maintaining open lines of communication can help navigate these human-related threats effectively. Therefore, it is recommended to conduct a comprehensive risk assessment and consult with local experts to identify and categorize the most relevant threats.
Screening Targets for Diagnosis and Treatment of Cognitive Dysfunction in Stroke through Transcriptome Combined with Machine Learning
Authors:   Department of Neurology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China, Chen Zhibin , Li Junxiong ,   Department of Acupuncture, Huadong Hospital Affiliated to Fudan University, Shanghai 20040, China, Hou Yangbo ,   Department of Neurology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China, Zhu Qiaoyan ,   Department of Neurology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China, Shi Zhizhen ,   Department of Neurology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
Published: March 2024

Post-Stroke Cognitive Impairment (PSCI) is one of the major complications after stroke. The evaluation of PSCI usually depends on neuropsychology tests, but the results of these tests are subjective and inaccurate. Need to find more objective indicators as identification markers of PSCI. In this study, we use machine learning to find biomakers of PSCI, and established regulatory networks at transcriptional level. Several gene such as ORC1, TOMM40L and SHISAL2A are identified biomakers, and several miRNA such as hsa-mir-130b-3p and hsa-mir-484 are interacted most tight with this biomakers genes. The results of this study help to better distinguish patients with PS and PSCI in clinical practice, and identifying relevant biomarker genes and miRNAs that can serve as potential therapeutic sites.
Catalytic Kinetic Resolution of Monohydrosilanes via Rhodium-Catalyzed Enantioselective Intramolecular Hydrosilylation
Authors: Gou Fei-Hu , Ren Fei , Wu Yichen , Wang Peng
Published: March 2024

The catalytic access of silicon-stereogenic organosilanes remains a big challenge, and largely depends on the desymmetrization of the symmetric precursors with two identical substitutes attached to the silicon atom. Here we report the construction of silicon-stereogenic organosilanes via catalytic kinetic resolution of racemic monohydrosilanes with good to excellent selectivity factors. Both Si-stereogenic dihydrobenzosiloles and Si-stereogenic monohydrosilanes could be efficiently accessed in one single operation via Rh-catalyzed enantioselective intramolecular hydrosilylation, employing (R,R)-Et-DuPhos as the optimal ligand. This catalytic protocol features mild conditions, low catalyst loading (0.1 mol% [Rh(cod)Cl]2), high stereoinduction (S factor up to 152), and excellent scalability. Moreover, further derivatizations led to the efficient synthesis of uncommon middle-size (7- and 8-membered) Si-stereogenic silacycles. Preliminary mechanistic study indicates this reaction might undergo a modified Chalk-Harrod mechanism.
Contemporary forest harvesting impacts on water quality and treatability
Authors: Bahramian Soosan , Shams Shoeleh , Williams Chris , Silins Uldis , Stone Micheal , Emelko Monica
Published: March 2024

Forested landscapes are critical source regions for the supply of drinking water globally. The increasing frequency and severity of climate shocks (e.g., wildfire, floods) in these regions can deteriorate source water quality. Forest harvesting has been proposed as an allied component of forest fuel management and pre-emptive mitigation of disturbance impacts on source water quality and treatability; however, forest harvesting can also deteriorate source quality and compromise treatability in the absence of sufficient operational response capacity. Critically, the impacts of forest harvesting on drinking water treatability have not been reported. Here, drinking water source quality and treatability impacts of three contemporary forest harvesting approaches (clear-cut with patch retention, strip-shelterwood cut, and partial cut) were evaluated in Alberta, Canada. Stream water turbidity, the concentration and character of dissolved organic matter, and disinfection by-product formation potential were evaluated over four years, in harvested and reference watersheds. No appreciable impacts of forest harvesting on water quality and treatability were observed. The results suggest that contemporary forest harvesting approaches may show promise as source water protection technologies for mitigating climate-exacerbated disturbance threats to drinking water treatability; however, further study is needed to establish causality and the contributions of other biotic and abiotic factors.
Influence of Chloride and Electrolyte Stability on Anode Passivation Layer Formation and its Dissolution in Mg Batteries Revealed by operando EQCM-D
Authors: Schick Benjamin W. , Vanoppen Viktor , Uhl Matthias , Kruck Matthias , Riedel Sibylle , Zhao-Karger Zhirong , Berg Erik J. , Hou Xu , Jacob Timo
Published: March 2024

Rechargeable magnesium batteries are promising for future energy storage. However, among other challenges, their practical application is hindered by low coulombic efficiencies of magnesium plating and stripping. Fundamental processes such as the formation, structure, and stability of passivation layers and the influence of different electrolyte components on them are still not fully understood. Here, we gain unique insights into the initial Mg plating and stripping cycles by comparing Mg bis(trifluoromethanesulfonyl)imide (Mg(TFSI)2)- and Mg tetrakis(hexafluoroisopropyloxy)borate (Mg[B(hfip)4]2)-based electrolytes, each with and without MgCl2, on gold electrodes by highly sensitive operando electrochemical quartz crystal microbalance with dissipation monitoring (EQCM-D), applying hydrodynamic spectroscopy. With the stable Mg[B(hfip)4]2-based electrolytes, highly efficient and interphase-free cycling is possible and passivation layers are attributed to electrolyte contaminants. These are forming and degrading during the so-called conditioning process. With the more reactive Mg(TFSI)2 based electrolyte, thick passivation layers with small pores are growing during cycling. We demonstrate that the addition of chloride lowers the amount of passivated Mg deposits in these electrolytes and accelerates the currentless dissolution of the passivation layer. This has a positive effect since we observe the most efficient cycling and uniform deposition when no interphase is present on the electrode.
Laser Post-Ionization Combined with Matrix-Free Laser Desorption/Ionization Enhances the Mass Spectrometry Imaging of Plant Metabolites
Authors: Bartels Benjamin , Güngör Erbil , Smith Donald , Schluepmann Henriette , Heeren Ron , Ellis Shane
Published: March 2024

While the benefits of mass spectrometry imaging (MSI) coupled with recently described laser post-ionization (LPI) techniques (e.g., MALDI-2) have been well explored for the study of mammalian systems, their benefits for spatial metabolomics of plants have not. Here, we demonstrate that matrix-free laser desorption/ionization (LDI) coupled with LPI can significantly increase the number of plant metabolites detectable in an MSI experiment, compared to LDI alone, including for many flavonoids. Moreover, while many aromatic compounds are detected as their radical cations, a result of the photoionization processes accessible using LPI, many compounds (e.g., non-UV active compounds) also experience a significant increase in the abundance of their protonated ions. This suggests that endogenous UV active compounds, such as flavonoids can act as a MALDI-like matrix in promoting charge transfer upon excitation by the laser pulse used for LPI. MSI datasets using LDI-LPI acquired from Azolla filiculoides reveal rich spectra, containing several thousand peaks, with very few background-related signals, including many poly glycosylated flavonoids. This work provides an avenue to significantly enhance the capabilities for studying region-specific flavonoid metabolism within plants.
Monomer-Recyclable Polyesters From CO2 and 1,3-Butadiene
Authors: Xu Jialin , Niu Yuxuan , Lin Bo-Lin
Published: March 2024

NOTE：This paper was first submitted for peer review at 31-Jan-2024, Manu-script ID: ja-2024-01537k. Recently, we found a very similar work published on ChemRxiv DOI: 10.26434/chemrxiv-2024-0p22l, therefore we decide to publish our work on ChemRxiv also. Synthesis of monomer-recyclable polyesters solely from CO2 and bulk olefins holds great potentials in significantly reducing CO2 emissions and addressing the issue of plastic pollutions. Due to the kinetic disadvantage of direct copolymerization of CO2 and bulk olefins compared to homopolymerization of bulk olefins, considerable research attention has been devoted to synthesis of polyester via the ring-opening polymerization (ROP) of a six-membered disubstituted lactone intermediate, 1,2-ethylidene-6-vinyl-tetrahydro-2H-pyran-2-one (𝜹-L), obtained from telomerization of CO2 and 1,3-butadiene. However, the conjugate olefin on the six-membered ring of 𝜹-L leads to serious Michael addition side reactions. Thus, selective ROP of 𝜹-L, which can precisely control the repeating unit for the production of polyesters potentially amenable to efficient monomer recycling, remains an unre-solved challenge. Herein, we report the first example of selective ROP of 𝜹-L using a combination of organobase and N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]urea as the catalytic system. Systematic modifications of the substituent of the urea shows that the presence of electron-deficient 3,5-bis(trifluoromethyl)-phenyl groups is the key to the extraordinary selectivity of ring opening over Michael addition. Efficient monomer recovery of poly(𝜹-L) was also achieved under mild catalytic conditions. This work proves that it is possible to synthesize monomer-recyclable polyester by only using CO2 and bulk olefin as the feedstock, provid-ing a new strategy to potentially fix CO2 in polymeric materials at large scales.
Pengaruh Digital Marketing, Efektivitas Iklan dan Komunikasi Pemasaran Terhadap Keputusan Pembelian Pada E-Commerce di Era Digital
Authors: Rochis Zaenur , Budi Setiawan Mulyo
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh Digital Marketing terhadap keputusan pembelian pada E-Commerce. Pengaruh Efektivitas Iklan terhadap keputusan pembelian pada E-Commerce. Pengaruh komunikasi pemasaran terhadap keputusan pembelian pada E-Commerce. Jenis penelitian ini adalah penelitian kuantitatif. Alat analisis yang digunakan adalah uji validitas dan uji reliabilitas program Smart (PLS) Versi 3.0.PLS, dengan berbasis pendekatan Variance Based Structural Equation Modelling (SEM). Penelitian ini dilakukan di Asa Beauty Msglow Semarang. Populasi penelitian ini berjumlah 400 orang. Teknik pengambilan sampel dalam penelitian ini menggunakan probability sampling dengan sampel 200 orang. Hasil penelitian menunjukkan bahwa Digital Marketing Berpengaruh Positif Dan Signifikan Terhadap keputusan pembelian pada E-Commerce Asa Beauty Msglow Semarang. Efektivitas iklan berpengaruh positif dan signifikan terhadap keputusan pembelian pada E-Commerce Asa Beauty Msglow Semarang.    Komunikasi pemasaran berpengaruh positif dan signifikan terhadap keputusan pembelian pada E-Commerce Asa Beauty Msglow Semarang.
Diet composition of the Mediterranean horse mackerel, Trachurus mediterraneus (Steindachner, 1868) (Osteichthyes: Carangidae), from the Aegean Sea
Authors: Bayhan Bahar , Sever Tuncay Murat , Kara Ali
Published: March 2024

Data on feeding habits in aquatic ecosystems are of great importance in determining the role that a certain fish species plays in its habitat and in related ecosystems. In this study, the diet composition of Mediterranean horse mackerel, Trachurus mediterraneus was investigated for 728 specimens from the central Aegean Sea to compare our data with those from other regions of the Mediterranean Sea and throughout all four seasons. Catches from five major groups were identified. Crustaceans (particularly copepods) proved to be the most important food item considering the index of relative importance (IRI). At least 58 different copepod species were identified. Abundant copepod species that occur in every season were Corycaeus sp., Oncaea media, Oncaea spp., Isias clavipes, Euterpina acutifrons and Oithona nana. Isias clavipes occurred only in spring, with all of them appearing in the diet with a %IRI >10. Although found in a relatively smaller quantity, teleost larvae ranked as the second most important prey in the overall diet, with increasing quantities in fish larger than 18.0 cm.
Soil mite communities (Acari: Gamasina) from different ecosystem types from Romania
Authors: Manu Minodora , Băncilă Raluca Ioana , Onete Marilena
Published: March 2024

The study aimed to characterize the distribution of soil mite populations (Acari: Gamasina) from several terrestrial ecosystems, some of them little studied in Romania as well as in Europe. We studied the Gamasina communities in seven ecosystem types from the Doftana Valley, Prahova County: Luzulo-Fagetum beech forest; Medio-European limestone beech forest of the Cephalanthero-Fagion; Pannonic woods with Quercus petraea and Carpinus betulus; Galio-carpinetum oak – hornbeam forests; Alpine rivers and their ligneous vegetation with Myricaria germanica; alluvial shrub, characteristic for a hilly-mountain area, with Salix purpurea; adjacent area to an inland cliff ecosystem. A total of 240 soil samples, 63 species and 475 individuals were analysed. The samples were taken from May 2006 till September 2010. The highest numerical abundance and species diversity was found in the area located nearby to an inland cliff, which is an early succession stage ecosystem. Considering the dominance and constancy indices quantified for mites from all investigated areas, the highest percent was recorded by the recedent-subrecedent and accessory-accidental species. Based on similarity index two different characteristic groups of gamasid populations were delimited: one for deciduous forests and one for shrubs. DCA ordination successfully handled the variation in soil mite species communities taking account of the soil type.
Variability of the proximal phalanx in warmblood and coldblood horses – morphological and structural analyses
Authors: Dzierzęcka Małgorzata , Komosa Marcin
Published: March 2024

Anatomical shape as well as bone geometry are important factors for the mechanical properties of stiffness and strength in bones. In the light of this statement, the primary aim of the study was to evaluate the variable forms of the proximal phalanx in different types of horses. Multivariate analyses of data from 81 horses revealed that the proximal phalanx has diverse spatial forms. Differences were observed particularly in the length of the bone and the breadth of its diaphysis. In horses with lighter morphotype, the phalanx is significantly narrower in its middle section. In the second stage of the study, geometrical parameters of the phalanx were analysed with the use of peripheral quantitative computed tomography (pQCT). Tomographic analysis was conducted at three levels: at 15%, 50% and 85% of the bone length. Based on the analysis, we concluded that most of the geometric parameters have higher values in coldbloods but only at the mid-diaphysis (50%) and at 85% of the bone length. Moreover, in coldblood horses, higher strength of the phalanx at these levels, expressed by Strength Strain Index, was observed. We did not observe any significant differences between warmblood and coldblood horses in the metaphyseal proximal region which is located at 15 % of the bone length.
The Golgi checkpoint: Golgi unlinking during G2 is necessary for spindle formation and cytokinesis
Authors: Mascanzoni Fabiola , Ayala Inmaculada , Iannitti Roberta , Luini Alberto , Colanzi Antonino
Published: March 2024

Entry into mitosis requires not only correct DNA replication but also extensive cell reorganization, including the separation of the Golgi ribbon into isolated stacks. To understand the significance of pre-mitotic Golgi reorganization, we devised a strategy to first block Golgi segregation, with the consequent G2-arrest, and then force entry into mitosis. We found that the cells forced to enter mitosis with an intact Golgi ribbon showed remarkable cell division defects, including spindle multipolarity and binucleation. The spindle defects were caused by reduced levels at the centrosome of the kinase Aurora-A, a pivotal spindle formation regulator controlled by Golgi segregation. Overexpression of Aurora-A rescued spindle formation, indicating a crucial role of the Golgi-dependent recruitment of Aurora-A at the centrosome. Thus, our results reveal that alterations of the pre-mitotic Golgi segregation in G2 have profound consequences on the fidelity of later mitotic processes and represent potential risk factors for cell transformation and cancer development.
Novelties in the Lichenoflora of the Vitimsky Reserve (East Siberia)
Authors:   Irkutsk State University, Lishtva A.V.
Published: March 2024

As a result of lichenological studies in the vicinity of Lake Oron (Vitimsky State Nature Reserve) and revision of herbarium material, 9 species of lichens were identified that had not previously been listed for a specially protected natural area. Some of the identified species have a wide distribution (Absconditella lignicola, Bryoria americana, Pyxine meissneriana, Trapeliopsis flexuosa and Multiclavula vernalis), and some have limited ranges covering only the eastern part of Asia, Alaska and Southern Siberia (“Cetraria” annae, Parmelina yalungana and Phaeophyscia dessecta), with “Cetraria” annae and Phaeophyscia dessecta so far they are known only for the territory of Russia. Some of these species (Absconditella lignicola, Trapeliopsis flexuosa and Multiclavula vernalis) probably have a wider distribution in the reserve, but without spore-bearing structures they are difficult to identify. Herbarium material attributed to Parmelina yalungana does not raise doubts regarding its species identity, however, the discovery of specimens with a macular upper surface in eastern Eurasia requires additional careful study.
Possible Role of Intestinal Microbiome Representatives in Biotransformation of Aryl- and Pyridyl-Containing Phosphines and their Derivatives According to 31P NMR Spectroscopy Data
Authors:   Irkutsk State University, Pendyukhova А. S. , Dranitsa I. S. ,   Irkutsk State University, Mikhailenko V. L. ,   Irkutsk State University, Pristavka А. А. ,   Irkutsk State University, Verkhoturova S. I. ,   A. E. Favorsky Irkutsk Institute of Chemistry SB RAS, Belogorlova N. A. ,   A. E. Favorsky Irkutsk Institute of Chemistry SB RAS, Arbuzova S. N. ,   A. E. Favorsky Irkutsk Institute of Chemistry SB RAS, Yurinova G. V. ,   Irkutsk State University, Salovarova V. P. ,   Irkutsk State University
Published: March 2024

Organophosphorus compounds (OPCs) are used in many areas of human activity. Unique physicochemical properties and high biological activity not only determine the applied value of OPCs but also give them the properties of xenobiotics that are harmful to human health, which largely depend on the state of the endogenous microbiota. The purpose of this work is to assess the effect of pyridyl- and aryl-containing phosphines, their oxides, and sulfides on the growth of Bifidobacterium bifidum and Escherichia coli and to identify possible patterns of biotransformation of OPCs using 31P NMR spectroscopy. Bacteria were cultivated in thioglycollate medium containing the tested phosphorus compounds. At the stationary growth phase was determined the cell concentration and were recorded spectra 31P NMR. It was shown that the most reliable (p<0,05) and opposite effect on the growth dynamics of both species of bacteria was exhibited by phosphine sulfides 1 and 3: PS1 (pyridyl) reduced the population reproduction rate by 35–40%, and PS3 (aryl) increased it by 45–60%. At the same time, OPCs themselves were most likely not metabolized. Phosphine oxides reduced the average titer of bacteria compared to the control, and PO3 caused complete cell elimination after 24 hours cultivation. In the medium with PO2 was identified PS2 appeared, which may be caused by the biologically mediated process of oxide-to-sulfide conversion. All phosphines are chemically labile and they were oxidized abiotically to oxides and sulfides. Formed sulfides could be the reason for a significant increase (to 35%) in the growth rate bacteria population both species. Five new unidentified organophosphorus compounds (UPC) were recorded on medias with B. bifidum, some of which may belong to the products of biotransformation of the original OPCs. Some organic phosphates, homologous to the phosphine oxides tested, have a δp value neighboring to the taken NMR spectra. This may indicate the way of their biological transformation: oxidation of the CP bond in the phosphine oxides to an ester bond of organic phosphates. This ability of bifidobacteria to metabolize OPCs will make it possible to develop a therapeutic strategy based on the use of B. bifidum as a microorganism that degrades phosphorus-containing xenobiotics.
Effect of Silicon-Containing Components of Nutrient Medium on the Synthesis of Exopolysaccharides by Silicate Bacteria
Authors:   East Siberian State University of Technology and Management, Ulakhanova L. A. , Gomboeva S. V. ,   East Siberian State University of Technology and Management, Tsyrenov V. Zh. ,   East Siberian State University of Technology and Management
Published: March 2024

Silicate bacteria have a wide biotechnological potential, they produce a large number of biologically active substances: enzymes that destroy silicates; fungicidal and antimicrobial compounds; phytohormones and exopolysaccharides (EPS). At the same time, they are able to use silicon-containing minerals as a source of additional energy. The literature provides studies on the destruction of polysilicon compounds by silicate bacteria of the speciessilicate bacteria. They are capable of destroying quartz, aluminosilicates with the release of Si, K and other elements. There is also information about stimulating the reproduction of silicate bacteria when growing on mineral media with the addition of silicon-containing components. At the same time, the influence of polysilicon compounds on the synthesis of exopolysaccharides by silicate bacteria is not considered. The exoglycans released by them are used in various industries: mining, oil production, pharmaceutical, food and cosmetic. The studies used isolated pure cultures of silicate bacteria, the biosynthetic activity of which was compared with strains of Paenibacillus mucilaginosus B7519 and B4901 (VKPM, GosNIIgenetics). Bacteria were isolated from the soils and sand of the Baikal region. The influence of silicon-containing components (bentonite, quartz sand) of the nutrient medium on crop growth and EPS synthesis was investigated. The positive effect of silicate minerals on the growth of isolated strains and museum cultures of P. mucilaginosus has been confirmed. Strain B-4901 had the highest amount of CFU/ml on nutrient media with both quartz sand and bentonite. The influence of siliconcontaining components on the EPS yield of the studied microorganisms has been established. The highest EPS yield was observed in the VSGUTU-2 strain on a nutrient medium with the addition of quartz sand, and the B7519 strain had the best synthesis on a medium with the addition of bentonite. The VSGUTU-1 strain showed the same yield of exopolysaccharides on two variants of media with silicon-containing components, whereas the amount of EPS in the B4901 strain did not increase with the addition of bentonite and quartz sand. The lowest EPS yields were on nutrient media without the addition of a silicon source.