bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemenary Figure 4 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: March 2023

PDF file, 40K, Intracellular ROS levels are reduced in metastatic BC cells. The distribution of superoxide levels in metastatic (blue) and non-metastatic (red) cell-lines.
Supplementary Figures 1-6 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: March 2023

PDF file - 296K, Figure S1: ICOS is mainly expressed by TA-Treg. Figure S2: pDC expanded Treg sustain suppressive activity. Figure S3: ICOS-L is highly expressed on R848-activated HD-pDC. Figure S4: ICOS blockade reduces Treg but not Tconv proliferation induced by pDC without impacting mDC/T cell activation. Figure S5: Strong IL-10 secretion in culture of BT single cell suspension. Figure S6: Correlation between TA-pDC and TA-Treg percentages in fresh primary BT and in retrospective IHC cohort
Supplementary Figure Legends 1-6, Table Legends 1-2 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: March 2023

PDF file - 68K
Supplementary Video 2 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: March 2023

MOV file - 4.3MB, Video for the mice receiving flavopiridol (day 90 after tumor cell injection via tail vein)
Supplementary Figure 3 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: March 2023

PDF file - 163K, FP/obatoclax up-regulates the BH3-only proteins Bim, Noxa, and Bik/NBK, primary events for interaction between FP and obatoclax
Supplementary Figure 6 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: March 2023

PDF file - 155K, RNF8 suppresses RAD51 assembly in BRCA1/53BP1-depleted 293T cells
Supplementary Figure 5 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: March 2023

PDF file - 657K, Depletion of 53BP1 rescues RAD51 assembly at DSB sites in BRCA1-depleted human cells
Supplementary Data 1-6 from Cardiac Inflammation after Local Irradiation Is Influenced by the Kallikrein-Kinin System
Authors: Sridharan Vijayalakshmi , Tripathi Preeti , Sharma Sunil K. , Moros Eduardo G. , Corry Peter M. , Lieblong Benjamin J. , Kaschina Elena , Unger Thomas , Thöne-Reineke Christa , Hauer-Jensen Martin , Boerma Marjan
Published: March 2023

PDF file - 82K, Echocardiography analysis at 3 months and 6 months after local heart irradiation
Supplementary Figure 1 from Genetic Ablation of Cav1 Differentially Affects Melanoma Tumor Growth and Metastasis in Mice: Role of Cav1 in Shh Heterotypic Signaling and Transendothelial Migration
Authors: Capozza Franco , Trimmer Casey , Castello-Cros Remedios , Katiyar Sanjay , Whitaker-Menezes Diana , Follenzi Antonia , Crosariol Marco , Llaverias Gemma , Sotgia Federica , Pestell Richard G. , Lisanti Michael P.
Published: March 2023

PDF file - 105K
Supplementary Figure 1 from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: March 2023

PDF file - 86K, TIC- specific aptamers display specificity for TICs.
Supplementary Figure 4 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: March 2023

PDF file - 91K, Nude mice bearing MB49 tumors were injected with Ad5/3-CMV-mCD40L, Ad5/3-Luc1 or PBS (Mock) on days 0,2 and 4. Eight days after first virus injection mice were killed and spleens and tumors were collected, smashed and cultured for 24 hours. Homogenates were analyzed for NK+ cells (left side) and CD19+ (right side). Results are presented as mean from 6 mice + SEM. *, P<0.05, **, P<0.01.
Supplementary Table 3 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages
Authors: Osawa Tsuyoshi , Tsuchida Rika , Muramatsu Masashi , Shimamura Teppei , Wang Feng , Suehiro Jun-ichi , Kanki Yasuharu , Wada Youichiro , Yuasa Yasuhito , Aburatani Hiroyuki , Miyano Satoru , Minami Takashi , Kodama Tatsuhiko , Shibuya Masabumi
Published: March 2023

PDF file - 24K, List of genes upregulated in response to hypoxia and nutrient starvation double stress in human and mouse cancer cells.
Supplementary Figure 3 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: March 2023

PDF file - 1651K, Absence of EMT-like protein changes following altered TWIST1 expression in melanoma cells
Supplementary Table 1 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages
Authors: Osawa Tsuyoshi , Tsuchida Rika , Muramatsu Masashi , Shimamura Teppei , Wang Feng , Suehiro Jun-ichi , Kanki Yasuharu , Wada Youichiro , Yuasa Yasuhito , Aburatani Hiroyuki , Miyano Satoru , Minami Takashi , Kodama Tatsuhiko , Shibuya Masabumi
Published: March 2023

PDF file - 37K, The sequence of specific primers for angiogenic factors and JMJD1A in real-time polymerase chain reaction analysis.
Supplementary Table 1, Figures 1-10, Methods from An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer
Authors: Ling Shizhang , Chang Xiaofei , Schultz Luciana , Lee Thomas K. , Chaux Alcides , Marchionni Luigi , Netto George J. , Sidransky David , Berman David M.
Published: March 2023

Supplementary Table 1, Figures 1-10, Methods from An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer
Supplementary Figure Legends 1-3 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells
Authors: Du Xiaoli , Qian Xiaolan , Papageorge Alex , Schetter Aaron J. , Vass William C. , Liu Xi , Braverman Richard , Robles Ana I. , Lowy Douglas R.
Published: March 2023

PDF file - 56K
Supplementary Table S2 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Authors: Ishii Nobuya , Harada Naoki , Joseph Eric W. , Ohara Kazuhiro , Miura Takaaki , Sakamoto Hiroshi , Matsuda Yutaka , Tomii Yasushi , Tachibana-Kondo Yukako , Iikura Hitoshi , Aoki Toshihiro , Shimma Nobuo , Arisawa Mikio , Sowa Yoshihiro , Poulikakos Poulikos I. , Rosen Neal , Aoki Yuko , Sakai Toshiyuki
Published: March 2023

Supplementary Table S2 - PDF file 163K, Kinase selectivity profile of CH5126766. The values of % competition at 10 �M CH5126766 in DiscoveRx's KINOMEscan for 256 kinases, Kd values for MEK and RAF enzymes in the same assay platform, and IC50 values against 25 kinases in biochemical enzyme assays were listed
Supplementary Figure S2 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Authors: Ishii Nobuya , Harada Naoki , Joseph Eric W. , Ohara Kazuhiro , Miura Takaaki , Sakamoto Hiroshi , Matsuda Yutaka , Tomii Yasushi , Tachibana-Kondo Yukako , Iikura Hitoshi , Aoki Toshihiro , Shimma Nobuo , Arisawa Mikio , Sowa Yoshihiro , Poulikakos Poulikos I. , Rosen Neal , Aoki Yuko , Sakai Toshiyuki
Published: March 2023

Supplementary Figure S2 - PDF file 92K, Inhibition of CRAF catalytic activity in a cell free CRAF assay with a peptide substrate of RAF family enzymes
Supplementary Figure 4 from Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence
Authors: Cui Hang , Kong Yahui , Xu Mei , Zhang Hong
Published: March 2023

PDF file - 20K, Data showing Notch3 transactivates p21 in a luciferase assay.
Supplementary Table 1 from miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells
Authors: Kovaleva Valentina , Mora Rodrigo , Park Yoon Jung , Plass Christoph , Chiramel Abhilash I. , Bartenschlager Ralf , Döhner Hartmut , Stilgenbauer Stephan , Pscherer Armin , Lichter Peter , Seiffert Martina
Published: March 2023

PDF file - 106K
Supplementary Table 2 from Targeting Pioneering Factor and Hormone Receptor Cooperative Pathways to Suppress Tumor Progression
Authors: Shah Supriya , Prasad Shikha , Knudsen Karen E.
Published: March 2023

PDF file - 1MB
Supplementary Table 1 from Targeting Pioneering Factor and Hormone Receptor Cooperative Pathways to Suppress Tumor Progression
Authors: Shah Supriya , Prasad Shikha , Knudsen Karen E.
Published: March 2023

PDF file - 2.3MB
Supplementary Figure 9 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma
Authors: Ostler Kelly R. , Yang Qiwei , Looney Timothy J. , Zhang Li , Vasanthakumar Aparna , Tian Yufeng , Kocherginsky Masha , Raimondi Stacey L. , DeMaio Jessica G. , Salwen Helen R. , Gu Song , Chlenski Alexandre , Naranjo Arlene , Gill Amy , Peddinti Radhika , Lahn Bruce T. , Cohn Susan L. , Godley Lucy A.
Published: March 2023

PDF file, 56K, Effect of ATRA on global DNA methylation.
Supplementary Figure 2 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma
Authors: Ostler Kelly R. , Yang Qiwei , Looney Timothy J. , Zhang Li , Vasanthakumar Aparna , Tian Yufeng , Kocherginsky Masha , Raimondi Stacey L. , DeMaio Jessica G. , Salwen Helen R. , Gu Song , Chlenski Alexandre , Naranjo Arlene , Gill Amy , Peddinti Radhika , Lahn Bruce T. , Cohn Susan L. , Godley Lucy A.
Published: March 2023

PDF file, 146K, DNMT3B7 expression levels in primary neuroblastoma tumors and induced cells.
Supplementary Table 1 from Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma
Authors: Suzuki Yoshiyuki , Mimura Kousaku , Yoshimoto Yuya , Watanabe Mitsuaki , Ohkubo Yu , Izawa Shinichirou , Murata Kazutoshi , Fujii Hideki , Nakano Takashi , Kono Koji
Published: March 2023

PDF file - 91K, Characteristics of the patients
Supplementary Figure Legends 1-5 from Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma
Authors: Suzuki Yoshiyuki , Mimura Kousaku , Yoshimoto Yuya , Watanabe Mitsuaki , Ohkubo Yu , Izawa Shinichirou , Murata Kazutoshi , Fujii Hideki , Nakano Takashi , Kono Koji
Published: March 2023

PDF file - 74K
Supplementary Figure S3 from Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks
Authors: Shen Changxian , Oswald Duane , Phelps Doris , Cam Hakan , Pelloski Christopher E. , Pang Qishen , Houghton Peter J.
Published: March 2023

Supplementary Figure S3 - PDF file 2191K, The mTOR Pathway Regulates ATM Checkpoint in Response to ICL via Sustaining FANCD2 in Rh30 Cells. A, model of the control of FANCD2 by PI3K-Akt-mTORC1-S6K1 axis. B, a hypothetic model of the regulation of ATM checkpoint activation and DNA damage repair in response to ICL by mTOR signaling
Supplementary Table 3 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

XLS file - 68K, Onto-Express Analysis for Cellular Components
Supplementary Figure Legends 1-6, Table Legends 1-6 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

PDF file - 81K
Supplementary Figure 2 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

PDF file - 56K, A secretory and inflammatory gene signature specific to CAFs
Supplementary Materials and Methods from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: March 2023

PDF file - 133K
Supplementary Table 2 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: March 2023

PDF file - 37K, Main characteristics of patients and tumor samples
Supplementary Figure 2 from eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies
Authors: Alain Tommy , Morita Masahiro , Fonseca Bruno D. , Yanagiya Akiko , Siddiqui Nadeem , Bhat Mamatha , Zammit Domenick , Marcus Victoria , Metrakos Peter , Voyer Lucie-Anne , Gandin Valentina , Liu Yi , Topisirovic Ivan , Sonenberg Nahum
Published: March 2023

PDF file - 2.7MB, Figure S2 contains data that show that cells with reduced levels of 4E-BP1/2 have increased resistance to the anti-neoplastic effects of PP242.
Supplementary Figure 5 from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: March 2023

PDF file - 250K, BMPs are downregulated, while TGFB1 is upregulated in breast cancer
Supplementary Table 1 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 57K, on clinical information
Supplementary Figure 5 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 322K, Showing the effect of siRNA PDK3, elesclomol and the combination DCA plus elesclomol on melanoma cell viability
Supplementary Figure 1 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 969K, Showing the expression of HIF-1a and PDK3 in human melanoma specimen and cell lines
Supplementary Figure 5 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: March 2023

PDF file - 25K, q-PCR data for miR-200a and miR-200c showing that PEG-encapsulated structures have decreased miR-200 levels at all loci following TGFbeta exposure
Supplementary Figure Legend from Dysregulated Expression of FOXM1 Isoforms Drives Progression of Pancreatic Cancer
Authors: Kong Xiangyu , Li Lei , Li Zhaoshen , Le Xiangdong , Huang Chen , Jia Zhiliang , Cui Jiujie , Huang Suyun , Wang Liwei , Xie Keping
Published: March 2023

PDF file - 103K
Supplementary Figure 2 from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: March 2023

PDF file, 440K, Characterization of SVF cell lines and effects of treatment with diphtheria toxin in vivo.
Supplementary Figure 1 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: March 2023

PDF file - 459K, Figure S1. HER2, HER3 and members of the PI3K signaling pathway are activated in HER2 amplified cell lines.
Supplementary Figure 1 from GM-CSF Promotes the Immunosuppressive Activity of Glioma-Infiltrating Myeloid Cells through Interleukin-4 Receptor-α
Authors: Kohanbash Gary , McKaveney Kayla , Sakaki Masashi , Ueda Ryo , Mintz Arlan H. , Amankulor Nduka , Fujita Mitsugu , Ohlfest John R. , Okada Hideho
Published: March 2023

PDF file, 65K, Confirmation of chimerism using enhanced green fluorescence protein (EGFP+) donor BM cells.
Supplementary Figure from NSD2 Is Recruited through Its PHD Domain to Oncogenic Gene Loci to Drive Multiple Myeloma
Authors: Huang Zheng , Wu Haiping , Chuai Shannon , Xu Fiona , Yan Feng , Englund Nathan , Wang Zhaofu , Zhang Hailong , Fang Ming , Wang Youzhen , Gu Justin , Zhang Man , Yang Teddy , Zhao Kehao , Yu Yanyan , Dai Jingquan , Yi Wei , Zhou Shaolian , Li Qian , Wu Jing , Liu Jun , Wu Xu , Chan Homan , Lu Chris , Atadja Peter , Li En , Wang Yan , Hu Min
Published: March 2023

PDF file, 989K, Depletion of NSD2 has only mild effects on myeloma cell proliferation. Supplementary Figure S2. NSD2 is important for tumorigenesis of t(4;14)+ myeloma cells. Supplementary Figure S3. PHD domains are important for cellular H3K36me2 activity of NSD2 but not in vitro enzymatic activity. Supplementary Figure S4. NSD2 activity mediates transcription activation of t(4;14)+ specific myeloma gene set. Supplementary Figure S5. NSD2 overexpression driven by t(4;14) translocation abolished global association of H3K36me2 with gene transcription. Supplementary Figure S6. NSD2 overexpression driven by t(4;14) translocation abolished positive correlation of H3K36me2 with gene transcription.
Supplementary Table 3 from Double Minute Chromosomes in Glioblastoma Multiforme Are Revealed by Precise Reconstruction of Oncogenic Amplicons
Authors: Sanborn J. Zachary , Salama Sofie R. , Grifford Mia , Brennan Cameron W. , Mikkelsen Tom , Jhanwar Suresh , Katzman Sol , Chin Lynda , Haussler David
Published: March 2023

PDF file, 142K, Data-based validation of exome analysis (Whole Genome Sequencing analysis).
Supplementary Figure 6 from Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma
Authors: Barrett Caitlyn W. , Ning Wei , Chen Xi , Smith Jesse Joshua , Washington Mary K. , Hill Kristina E. , Coburn Lori A. , Peek Richard M. , Chaturvedi Rupesh , Wilson Keith T. , Burk Raymond F. , Williams Christopher S.
Published: March 2023

PDF file - Gpx3 expression is highest in Caco2 cells. A) Gpx3 expression was analyzed within a cohort of colorectal cancer cell lines. The graph demonstrates fold-change of triplicate samples after analysis by the delta deltaCt method. B) Western blot for Gpx3 expression in Caco2 and HCT116 cells.
Supplementary Figure 2 from ATR Inhibition Broadly Sensitizes Ovarian Cancer Cells to Chemotherapy Independent of BRCA Status
Authors: Huntoon Catherine J. , Flatten Karen S. , Wahner Hendrickson Andrea E. , Huehls Amelia M. , Sutor Shari L. , Kaufmann Scott H. , Karnitz Larry M.
Published: March 2023

PDF file - 95K, Supplementary Figure 2. The Chk1 inhibitor LY2603618 sensitizes OVCAR-8 and PEO1 cells to gemcitabine.
Supplementary Table 3 from AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial–Mesenchymal Transition and Suppresses Tumor Growth and Progression
Authors: Shi Zhendong , Zhang Junxia , Qian Xiaomin , Han Lei , Zhang Kailiang , Chen Luyue , Liu Jilong , Ren Yu , Yang Ming , Zhang Anling , Pu Peiyu , Kang Chunsheng
Published: March 2023

XLSX file - 596K, The differential expression genes between AC1MMYR2 and DMSO 6-hour treatment were determined after RNA-Seq assay.
Supplementary Table 2 from Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Authors: Teitz Tal , Inoue Madoka , Valentine Marcus B. , Zhu Kejin , Rehg Jerold E. , Zhao Wei , Finkelstein David , Wang Yong-Dong , Johnson Melissa D. , Calabrese Christopher , Rubinstein Marcelo , Hakem Razqallah , Weiss William A. , Lahti Jill M.
Published: March 2023

XLSX file - 175K, Table S2- Data on the genes that differ in expression between primary tumors Th- MYCN, Caspase-8 wild type with no BMM, and primary tumors Th-MYCN, deficient caspase-8 without BMM (p<0.05).
Supplementary Figures 1 - 7 from Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Authors: Teitz Tal , Inoue Madoka , Valentine Marcus B. , Zhu Kejin , Rehg Jerold E. , Zhao Wei , Finkelstein David , Wang Yong-Dong , Johnson Melissa D. , Calabrese Christopher , Rubinstein Marcelo , Hakem Razqallah , Weiss William A. , Lahti Jill M.
Published: March 2023

PDF file - 709K, Figure S1. Correlation of relative mean fold changes in expression of genes and microRNAs of the mouse tumor groups by expression- array and by quantitative RT-PCR. Figure S2. Levels of caspase-8 protein in primary tumors and BM secondary tumors. Figure S3. Primary tumors from wild-type or caspase-8 deficient (fl/ko, fl/fl or wt/ko caspase-8) mice had neuroblastoma morphology and stained positive for neuronal markers typical for neuroblastoma. Figure S4. Age at maximum tumor burden of neuroblastoma primary tumors in the Th-MYCN mouse groups. Figure S5. Measuring apoptosis levels by immunostaining for cleaved caspase-3. Figure S6. MYCN expression in the primary Th-MYCN, Th-Cre neuroblastoma tumors. Figure S7. Secondary tumors observed in both the Th-MYCN Caspase-8 wt/wt and the Th-MYCN deficient caspase-8 mouse models.
Supplementary Tables 1 - 2 from Neuropilin-2 Is Upregulated in Lung Cancer Cells during TGF-β1–Induced Epithelial–Mesenchymal Transition
Authors: Nasarre Patrick , Gemmill Robert M. , Potiron Vincent A. , Roche Joëlle , Lu Xian , Barón Anna E. , Korch Christopher , Garrett-Mayer Elizabeth , Lagana Alessandro , Howe Philip H. , Drabkin Harry A.
Published: March 2023

PDF file - 97K, shRNA target sequences (S1); Primers used for quantitative RT-PCR (S2).
Supplementary Figure 1 from Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma
Authors: Ara Tasnim , Nakata Rie , Sheard Michael A. , Shimada Hiroyuki , Buettner Ralf , Groshen Susan G. , Ji Lingyun , Yu Hua , Jove Richard , Seeger Robert C. , DeClerck Yves A.
Published: March 2023

Supplementary Figure 1 - PDF file 231K, Inhibition of STAT3 activation in CHLA-255 cells by anti-IL-6R blocking antibody. A, Expression of pSTAT3 and STAT3 in CHLA-255 cells was examined by Western blot analysis as in Fig. 1A. When indicated, cells were treated with tocilizumab (2�g/mL) for 12 hours before treatment with IL-6 with or without sIL-6R. The data are representative of 2 separate experiments showing similar results. B, Nuclear extracts from CHLA-255 treated with IL-6 and sIL-6R in the presence and absence of tocilizumab as above described were examined for STAT3 DNA-binding activity by EMSA as indicated in Materials and Methods. Lane 8 is same as lane 5, except for the addition of a �supershifting� anti-STAT3 antibody also added to lane 2 (DU145 control). Top band (labeled STAT3) represents STAT3/STAT3 homodimers bound to DNA. C, CHLA-255 transfected with a STAT3 Firefly luciferase vector and a Renilla luciferase control vector were treated with IL-6 (10ng/mL) alone or in combination with sIL-6R (25ng/mL) as shown in Fig. 1 in the absence or presence of tocilizumab (4�g/mL). After 24 hours, the activity of the STAT3 reporter was examined by Dual Luciferase assay as indicated in Materials and Methods. The data represent the mean (�SD) ratio Firefly/Renilla luciferase activity from five samples for each experimental condition
Supplementary Methods and Figures and Table from KIT Signaling Governs Differential Sensitivity of Mature and Primitive CML Progenitors to Tyrosine Kinase Inhibitors
Authors: Corbin Amie S. , O'Hare Thomas , Gu Zhimin , Kraft Ira L. , Eiring Anna M. , Khorashad Jamshid S. , Pomicter Anthony D. , Zhang Tian Y. , Eide Christopher A. , Manley Paul W. , Cortes Jorge E. , Druker Brian J. , Deininger Michael W.
Published: March 2023

PDF file, 421K, Supplementary Figure 1: Specificity of imatinib, dasatinib, PPY-A, BAW667, and a SCF-blocking antibody on Mo7ep210BCR-ABL1 cells. Supplementary Figure 2: Comparison of CFU-GM colony formation upon sole BCR-ABL1 inhibition (PPY-A), sole KIT inhibition or dual BCR-ABL1/KIT inhibition. Supplementary Figure 3: Inhibition of KIT in human cells through use of a lentiviral vector for simultaneous expression of shKIT and GFP . Supplementary Figure 4: Analysis of CML CFU-GM colony growth following removal of the individual cytokines. Supplementary Figure 5: BCR-ABL1 and KIT signaling influence activation of AKT associated with a reduction of Foxo3A. Supplementary Table 1. Activity profile of BAW667.
Supplementary Movie 6 from Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Authors: Belaid Amine , Cerezo Michaël , Chargui Abderrahman , Corcelle–Termeau Elisabeth , Pedeutour Florence , Giuliano Sandy , Ilie Marius , Rubera Isabelle , Tauc Michel , Barale Sophie , Bertolotto Corinne , Brest Patrick , Vouret-Craviari Valérie , Klionsky Daniel J. , Carle Georges F. , Hofman Paul , Mograbi Baharia
Published: March 2023

AVI file - 645K, Video 6 (related to Fig. 6A) is a time-lapse recording showing that the ATG5-depleted A549 cells formed numerous ectopic furrows in addition to a wider-than-normal equatorial cleavage furrow.
Supplementary Methods from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Methods PDF file 75K, Supplementary Methods describing hybridoma production and associated ELISA
Supplementary Movie 4 from Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Authors: Belaid Amine , Cerezo Michaël , Chargui Abderrahman , Corcelle–Termeau Elisabeth , Pedeutour Florence , Giuliano Sandy , Ilie Marius , Rubera Isabelle , Tauc Michel , Barale Sophie , Bertolotto Corinne , Brest Patrick , Vouret-Craviari Valérie , Klionsky Daniel J. , Carle Georges F. , Hofman Paul , Mograbi Baharia
Published: March 2023

AVI file - 2112K, Video 4 (related to Fig. 2F) illustrates the failed abscission of a mononucleated a3-/- cell that exited mitosis as a binucleated cell after 18 attempts at cleavage furrow formation. Note that this cell developed ectopic furrows, which led to the formation of anuclear fragments that fused back to the cell.
Supplementary Movie 2 from Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Authors: Belaid Amine , Cerezo Michaël , Chargui Abderrahman , Corcelle–Termeau Elisabeth , Pedeutour Florence , Giuliano Sandy , Ilie Marius , Rubera Isabelle , Tauc Michel , Barale Sophie , Bertolotto Corinne , Brest Patrick , Vouret-Craviari Valérie , Klionsky Daniel J. , Carle Georges F. , Hofman Paul , Mograbi Baharia
Published: March 2023

AVI file - 875K, Video 2 (related to Fig. 2D) shows the delayed abscission of an a3-/- cell that remained connected by an intracellular bridge for up to 8 h 45 min before separating.
Supplementary Figure 3 from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Figure 3 PDF file 71K,Supplemental Figure 3: Lack of cytoplasmic ALCAM corresponds with poor patient outcome
Supplementary Figure from KEAP1-Dependent Synthetic Lethality Induced by AKT and TXNRD1 Inhibitors in Lung Cancer
Authors: Dai Bingbing , Yoo Suk-Young , Bartholomeusz Geoffrey , Graham Ryan A. , Majidi Mourad , Yan Shaoyu , Meng Jieru , Ji Lin , Coombes Kevin , Minna John D. , Fang Bingliang , Roth Jack A.
Published: March 2023

PDF file, 589K, Combination of Auranofin and MK2206 induced PARP cleavage in H460 cells with re-expression of functional KEAP1.
Supplementary Figure 1 from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Figure 1 PDF 2097K,Supplemental Figure 1: Multi-species sequence alignment was carried our using the Geneious� bioinformatics software
Supplementary Figure Legend from KEAP1-Dependent Synthetic Lethality Induced by AKT and TXNRD1 Inhibitors in Lung Cancer
Authors: Dai Bingbing , Yoo Suk-Young , Bartholomeusz Geoffrey , Graham Ryan A. , Majidi Mourad , Yan Shaoyu , Meng Jieru , Ji Lin , Coombes Kevin , Minna John D. , Fang Bingliang , Roth Jack A.
Published: March 2023

PDF file, 23K.
Supplementary Figure 6 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 1MB, SFigure 6 shows that proliferation of conventional T cells is not enhanced in tumor bearing mice and metastatic colorectal cancer patients and is not modulated by anti-VEGF treatment
Supplementary Figure 5 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 954K, SFigure 5 shows that bevacizumab associated with chemotherapy do not induce lymphopenia or variations of CD4+ and CD8+ T cells in metastatic colorectal cancer patients
Supplementary Figure 4 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 152K, SFigure 4 shows that anti-VEGF or sunitinib only modulate Treg and not other T cell subsets in tumors
Supplementary Figure 5 from Quantitative In Vivo Characterization of Intracellular and Extracellular pH Profiles in Heterogeneous Tumors: A Novel Method Enabling Multiparametric pH Analysis
Authors: Lutz Norbert W. , Le Fur Yann , Chiche Johanna , Pouysségur Jacques , Cozzone Patrick J.
Published: March 2023

PDF file - 34K, Gaussian curve fitting to 3-APP 31P NMR spectral regions of phantoms and mouse tumors for varying numbers and intensities of pHe modes.
Supplementary Figure 3 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 1.3MB, SFigure 3 shows that anti-VEGFA or sunitinib treatments only modulate Treg and not other T cell subsets in spleens of tumor-bearing mice
Supplementary Figure 2 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 1.5MB, SFigure 2 shows that Treg decrease after anti-angiogenic treatments is not correlated with tumor size
Supplementary Figure 1 from VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer
Authors: Terme Magali , Pernot Simon , Marcheteau Elie , Sandoval Federico , Benhamouda Nadine , Colussi Orianne , Dubreuil Olivier , Carpentier Antoine F. , Tartour Eric , Taieb Julien
Published: March 2023

PDF file - 831K, SFigure 1 shows that Treg decrease is maintained after 3 weeks of anti-VEGFA treatment
Supplementary Figure 1 from Quantitative In Vivo Characterization of Intracellular and Extracellular pH Profiles in Heterogeneous Tumors: A Novel Method Enabling Multiparametric pH Analysis
Authors: Lutz Norbert W. , Le Fur Yann , Chiche Johanna , Pouysségur Jacques , Cozzone Patrick J.
Published: March 2023

PDF file - 23K, Graphical presentation of a conventional histogram based on bins (buckets), and an analogous histogram derived from digital pH curve points.
Supplementary Table 1 from Oncogenic Herpesvirus HHV-8 Promotes Androgen-Independent Prostate Cancer Growth
Authors: Mygatt Justin G. , Singhal Adit , Sukumar Gauthaman , Dalgard Clifton L. , Kaleeba Johnan A.R.
Published: March 2023

PDF file - 112K, Microarray analysis of altered genes in HHV-8-infected LNCaP-V219 cells cultured in androgen depleted (CSFBS) conditions.
Supplementary Figure 5 from Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Authors: Ardestani Shidrokh , Li Bin , Deskins Desirae L. , Wu Huiyun , Massion Pierre P. , Young Pampee P.
Published: March 2023

PDF file - 107K, Tumor inhibitory effect of mTNFα requires the presence of TNFα receptors.
Supplementary Figure 1 from Oncogenic Herpesvirus HHV-8 Promotes Androgen-Independent Prostate Cancer Growth
Authors: Mygatt Justin G. , Singhal Adit , Sukumar Gauthaman , Dalgard Clifton L. , Kaleeba Johnan A.R.
Published: March 2023

PDF file - 149K, Long-term infection and reactivation of HHV-8 in DU145 cells.
Supplementary Table 1 from Critical Role for the Receptor Tyrosine Kinase EPHB4 in Esophageal Cancers
Authors: Hasina Rifat , Mollberg Nathan , Kawada Ichiro , Mutreja Karun , Kanade Geetanjali , Yala Soheil , Surati Mosmi , Liu Ren , Li Xiuqing , Zhou Yue , Ferguson Benjamin D. , Nallasura Vidya , Cohen Kenneth S. , Hyjek Elizabeth , Mueller Jeffery , Kanteti Rajani , El Hashani Essam , Kane Dorothy , Shimada Yutaka , Lingen Mark W. , Husain Aliya N. , Posner Mitchell C. , Waxman Irving , Villaflor Victoria M. , Ferguson Mark K. , Varticovski Lyuba , Vokes Everett E. , Gill Parkash , Salgia Ravi
Published: March 2023

PDF file - 66K, This table contains the detailed immunohistochemical data scoring depicted in Figure A and B
Supplementary Table 4 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 200K, MLH1 expression in pancreatic lesions.
Supplementary Figures from Complementary Populations of Human Adipose CD34+ Progenitor Cells Promote Growth, Angiogenesis, and Metastasis of Breast Cancer
Authors: Orecchioni Stefania , Gregato Giuliana , Martin-Padura Ines , Reggiani Francesca , Braidotti Paola , Mancuso Patrizia , Calleri Angelica , Quarna Jessica , Marighetti Paola , Aldeni Chiara , Pruneri Giancarlo , Martella Stefano , Manconi Andrea , Petit Jean-Yves , Rietjens Mario , Bertolini Francesco
Published: March 2023

PDF file, 1926K, Supplementary Fig. 1 Decreasing levels of CD34 expression among some ASCs. Supplementary Fig. 2: HEV-specific MECA 79 expression. Supplementary Fig. 3: Renal capsule invasion assay. Supplementary Fig. 4: z-stack 3D studies. Supplementary Fig. 5: z-stack 3D studies (cont). Supplementary Fig. 6: EMT morphology. Supplementary Fig. 7: Cell identification in time lapse studies. Supplementary Fig. 8: CCRL2 expression in WAT cells.
Supplementary Figure Legends and Tables from Complementary Populations of Human Adipose CD34+ Progenitor Cells Promote Growth, Angiogenesis, and Metastasis of Breast Cancer
Authors: Orecchioni Stefania , Gregato Giuliana , Martin-Padura Ines , Reggiani Francesca , Braidotti Paola , Mancuso Patrizia , Calleri Angelica , Quarna Jessica , Marighetti Paola , Aldeni Chiara , Pruneri Giancarlo , Martella Stefano , Manconi Andrea , Petit Jean-Yves , Rietjens Mario , Bertolini Francesco
Published: March 2023

PDF file, 105K, Supplementary Table 1, Monoclonal antibodies used in the study. Supplementary Table 2, EMT gene expression in luminal breast cancer cells ZR75-1 in transwell culture with human WAT totatl CD34+ cells, ECs and ASCs.
Supplementary Table 2 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 200K, GLI1 expression in pancreatic lesions.
Supplementary Figure 2 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 1878K, MLH1 copy number status and the tolerance to MNU.
Supplementary Figure 1 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 1384K, BHLHE41 promoter and GLI-binding sequence.
Supplementary Figure Legend from Autocrine Motility Factor Promotes HER2 Cleavage and Signaling in Breast Cancer Cells
Authors: Kho Dhong Hyo , Nangia-Makker Pratima , Balan Vitaly , Hogan Victor , Tait Larry , Wang Yi , Raz Avraham
Published: March 2023

PDF file - 71K
Supplementary Methods and Figure Legend from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 138K
Supplementary Figure 6 from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 428K, Supplementary Figure 6. Depletion of immune cell subsets with mAb is successful in tumor-bearing WT mice.
Supplementary Figure 5 from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 164K, Supplementary Figure 5. IFN-gamma and vorinostat act in concert to enhance tumor cell imunogenicity.
Supplementary Figure 4 from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 24K, TLR4 function is not affected by TLR5 F616L in primary immune cells.
Supplementary Methods from Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases
Authors: Zhao Hong , Jin Guangxu , Cui Kemi , Ren Ding , Liu Timothy , Chen Peikai , Wong Solomon , Li Fuhai , Fan Yubo , Rodriguez Angel , Chang Jenny , Wong Stephen TC
Published: March 2023

PDF file - 59K
Supplementary Figure S6 from Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity
Authors: Kwong Brandon , Gai S. Annie , Elkhader Jamal , Wittrup K. Dane , Irvine Darrell J.
Published: March 2023

Supplementary Figure S6 PDF file 66K, Therapeutic efficacy of prolonged Lip-�CD137 + Lip-IL-2Fc i.t. therapy in dual-tumor B16F10 model
Supplementary Table 7 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

XLS file - 48K, Sources of Small-Molecule Kinase Inhibitors
Supplementary Table 6 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

XLS file - 73K, Cumulative Gene Target Scores
Supplementary Table 5 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

XLS file - 224K, 151 Patient Gene Target Scores
Supplementary Table 4 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

XLS file - 552K, 151 Patient Drug Curve Raw Data Points
Supplementary Table 3 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

XLS file - 132K, 151 Patient IC50s