bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of Genetic Diversity Among Crataegus Species (Hawthorn) Using ISSR Markers in Northwestern of Iran
Authors: Beigmohamadi Mina , Rahmani Fatemeh , Mirzaei Leila
Published: November 2021

Background: Crataegus spp. (Hawthorn) are used for horticultural and medicinal purposes.
Objectives: In the present study, the genetic relationships among the five Iranian Crataegus species were evaluated by Inter Simple Sequence Repeats (ISSR) molecular marker
Methods: PCR reactions were performed using six primers (811, 827, 834, 845, 856, and 868) and genetic similarity was calculated based on Jacquard’s similarity coefficient.
Results: Six primers generated 79 products in total, of which 71 were polymorphic (89.9%), with an average of 13.1 bands per primer. The percentage of polymorphic bands ranged from 77 to 100. Primer 856 produced the highest number of bands, while the lowest was generated by primer 845. The Jacquard’s similarity coefficient, derived from ISSR marker analysis, ranged from 0.164 to 0.337, indicating high genetic variation among Crataegus species in Iran.
Conclusion: This study provides important data for identifying species relationships and helps develop plant breeding strategies to improve the medicinal properties of this genus in the future.
A Case of Erythema Multiforme Caused by Sildenafil Plus Tramadol
Authors: Ghanbarzamani Amir Hossein , Salehifar Ebrahim , Kazemian Kaveh
Published: November 2021

In this report, we present a 29-year-old man who experienced EM five days after using sildenafil and tramadol. Based on clinical examination and history, the diagnosis of EM was made confirmed via skin biopsy, which found intra-epidermal bulla filled by fibrinous exudate, some mononuclear cells, and a few eosinophils. The spongiotic epidermis showed lichenoid interface dermatitis, eosinophilic spongiosis, and necrolysis, consistent with EM diagnosis. Fluocinolone, 0.025% ointment, was prescribed for the patient, and the lesions healed after two weeks of treatment.
COVID‐19 Pandemic: Management and Challenges
Authors: Saberi-Hasanabadi Parisa , Mohammadi Hamidreza
Published: November 2021

Background: Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‑CoV‑2). The outbreak was first identified in Wuhan, China, in December 2019.
Objectives: This review gives a bird’s-eye view of the COVID-19 pandemic and its various effects on human society. Since knowledge about this virus is rapidly evolving, readers are urged to update themselves regularly.
Methods: In this review, our searching was performed on international databases of Embase, ScienceDirect, Scopus, PubMed, and Web of Science (ISI) from October 2019 to June 2020.
Results: Most patients infected with COVID‑19 have mild symptoms. Approximately 15% of patients have severe pneumonia, and about 5% acute distress syndrome or organ failure. In the absence of definitive treatment and vaccines, the most effective measure is to prevent infection, particularly in those at high risk of taking the severe form of the disease with adverse outcomes. Pharmacotherapy is essentially supportive; the role of antiviral agents is yet to be established. The commonest drugs used in treating this viral disease are tocilizumab, remdesivir, favipiravir, and camostat mesilate. Also, drugs related to malaria, AIDS, and Ebola, such as hydroxychloroquine, are widely used. Based on physical examinations alone, it is impossible to comment with certainty in mild cases of the disease. Accordingly, a wide range of methods is used for diagnosing and treating the disease. Various variables in reducing the severity of the epidemic and the effects of the virus require special management at the national, regional, and global levels.
Conclusion: This review summarizes the latest findings in safety, management, and public services related to the COVID-19 virus epidemic.
L-arginine Ameliorated Mitochondrial Oxidative Damage Induced by Sub-chronic Exposure to Cadmium in Mice Kidney
Authors: Shaki Fatemeh , Teymoori Melika , Motafeghi Farzaneh Sadat , Hemmati Nasibeh , Arab-Nozari Milad
Published: November 2021

Background:Cadmium is a heavy metal that can cause various injuries in the body, including nephrotoxicity. L-Arginine is a metal chelator that can prevent oxidative damage caused by oxygen free radicals.
Objectives:This study aimed to investigate the effect of L-arginine in inhibiting mitochondrial toxicity induced by subchronic cadmium exposure in the kidney of male mice.
Methods: A total of 42 male mice were randomly divided into six groups (n=6): control (normal saline), cadmium (2 mg/kg), cadmium (2 mg/kg) plus three doses of L-arginine (50, 100, and 200 mg/kg) and finally cadmium (2 mg/kg) plus vitamin C (500 mg/kg). After 42 days, the animals were anesthetized with ketamine/xylazine. Their kidney tissues were removed, and mitochondrial fractions were isolated. Oxidative stress factors and mitochondrial damage parameters (MTT, swelling, and mitochondrial membrane potential) were measured in renal isolated mitochondria. Also, evaluation of Blood Urea Nitrogen (BUN) and Creatinine (Cr) tests were done.
Results: Significant rise in BUN and Cr were observed in cadmium-treated mice (P<0.05). Cadmium enhanced oxidative stress in the kidney via increasing lipid peroxidation and oxidation of protein and glutathione. It caused significant mitochondrial dysfunction, mitochondrial membrane potential collapse, and swelling in isolated mitochondria (P<0.05). L-Arginine significantly ameliorated cadmium-induced oxidative stress and mitochondrial damage (P<0.05). Furthermore, a significant reduction in serum BUN and Cr were observed in L-arginine received group (P<0.05).
Conclusion: The results showed that L-arginine has significant protective effects against cadmium-induced renal toxicity in male mice.
A Comparative Study of Apigenin Content and Antioxidant Potential of CosmosBipinnatus Transgenic Root Culture
Authors: Bijani Soroush , Gharari Zahra , Ahmadnia Alireza , Danafar Hossein , Sharafi Ali
Published: November 2021

Background: Flavonoid-derived components have been studied for their therapeutic properties.
Objectives: Apigenin has shown remarkable antioxidant and anti-inflammatory features, so we should have a reliable source of apigenin.
Methods: In this study, we used high-performance liquid chromatography method to compare the amount of apigenin in flower, root, leaf, and stem of three varieties of osmos bipinnatus, i.e., ‘Dazzler,’ ‘Xanthos,’ ‘Sensation Pinkie’, and in transgenic root culture of C. bipinnatus ‘Dazzler’. Besides, the antioxidant activity of C. bipinnatus ‘Dazzler’ transgenic root culture was evaluated using Ferric Reducing Antioxidant Power (FRAP) assay.
Results: Dazzler variety flowers showed the highest recovery of apigenin with 0.799 mg/100 mg Dry Weight (DW). However, the Sensation pinkie variety leafs had the lowest recovery with 0.089 mg/100mg. Apigenin content in transformed roots (0.797 mg/100 mg DW) of C. bipinnatus ‘Dazzler’ was significantly higher than non-transformed roots (0.42 mg/100 mg DW). The ethanolic extract of hairy root showed the FRAP value of 668.1 µM Fe2+/mg that was comparatively more than the wild root FRAP value (426.2 µM Fe2+/mg).
Conclusion: In conclusion, the presence of apigenin in high amounts in hairy root cultures of C. bipinnatus ‘Dazzler’ indicates its great potential for the future pharmaceutical industry.
Doctors Perception of the Use of Hydroxychloroquine as Prophylaxis for COVID-19 Infection
Authors: Rana Proteesh , Ghadlinge Manik , Singh Pratap , Chandane R. D. , Khanna Arjun
Published: November 2021

Background: The National Task force constituted by the Indian Council of Medical Research (ICMR) and various International agencies has recommended the use of Hydroxychloroquine (HCQ) as prophylaxis for Coronavirus Disease 2019 (COVID-19). This measure was taken because of the urgent need to protect high-risk individuals like Health Care Workers (HCW) from contracting COVID-19.
Objectives: This study aimed to assess the awareness, attitudes, and practices on using HCQ as prophylaxis to prevent COVID-19 infection.
Methods: A cross-sectional study was conducted among the doctors working in Dr RML Hospital, New Delhi, India, a tertiary care public hospital involved in the care of COVID-19 patients. The invitation to participate was electronically circulated, and the consenting participants were allowed to access an online survey. The survey had a total of 23 questions that were designed to understand the awareness, perception, and practices of doctors regarding the use of HCQ as prophylaxis in COVID-19.
Results: About 147 doctors participated in this survey. The major source of knowledge regarding HCQ prophylaxis was quoted as regulatory agencies (44%), particularly ICMR, and the main indication was reported as being a healthcare worker (60%). Most of the participants (91%) believed that the HCQ effect is not clear and felt more scientific data regarding the use of HCQ as prophylaxis for COVID-19. But many doctors (51%) still recommend using HCQ to their colleagues.
Conclusion: In this study, we observed that most doctors were aware of the recommendations regarding the HCQ prophylaxis in COVID-19 and had good adherence to therapy but felt the need for more concrete scientific evidence for using HCQ.
Evaluation of Susceptibility and Resistance of Human Infectious Bacteria and Identification of Bioactive Compounds in Pistacia atlantica, Cassia absus, and Quercus persica
Authors: Alamholo Mostafa , Amraie Yosof
Published: November 2021

Background: The antimicrobial activity of plants has long been considered an effective mechanism for controlling pathogenic microorganisms.
Objectives: This study aimed to identify phytochemical compounds of the seed extracts from ethnomedicinal plants of Pistacia atlantica, Cassia absus, and Quercus persica with Gas Chromatography-Mass Spectrometry (GC-MS) and investigation of their antibacterial and antioxidant activities.
Methods: The seeds were collected from Lorestan Province, Iran. Their antibacterial and antiradical activities were analyzed by disk-diffusion and 2,2-diphenyl-1-picrylhydrazyl assays, respectively. Ethanol (96%), methanol (80%), and distilled water extracts were obtained by the maceration method. The methanol extract was used for the analysis of chemical compositions.
Results: About 40, 31, and 8 compounds were identified by GC-MS in the seeds of C. absus, P. atlantica, and Q. persica, respectively. Results indicated that 2,4-di-tert-butylphenol (36.043%) and tetradecanoic acid (4.92%) were dominated in the seed extracts of C. absus. However, germacyclopetene (38.119%) and 1,2,3-benzenetriol (8.115%) were dominated in the seed extracts of P. atlantica. Furthermore, 5H-tetrazole-5-thione, 1,4-dihydro-1,4-dimethy (38.505%), and tetradecanoic acid (30.546%) were dominated in the seed extracts of Q. persica. The highest inhibitory activity against Micrococcus luteus was observed on the methanol extract of C. absus with ascorbic acid. A significant difference was observed between the Inhibitory Concentration (IC50) values of methanol extract of C. absus with ascorbic acid.
Conclusion: Because of the presence of antimicrobial compounds in the tested ethnomedicinal plants, they can be used to synthesize new antimicrobial drugs in medicinal and pharmaceutical sciences.
Hemorrhagic Events in Patients Receiving Heparin or Enoxaparin in Combination With Oral Antithrombotics, NSAIDs, and Antiplatelet Medications: A Multi-Center Case-Series Study
Authors: Ghanbarzamani Amirhossein , Sefidani Forough Aida , Salamzadeh Jamshid , Fahimi Fanak
Published: November 2021

Background: Hemorrhagic events are amongst the significant adverse effects of injectable anticoagulants such as heparin and enoxaparin. This undesirable effect needs close monitoring of their use for clinically relevant drug-drug interactions.
Objectives: To study the rate of hemorrhagic events, the anatomical site, and the severity of the bleeding in patients receiving heparin or enoxaparin in combination with clopidogrel, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), and warfarin.
Methods: We designed a prospective, multi-center, case-series study. Patients admitted to two teaching hospitals who received either an NSAID, or warfarin, or clopidogrel were evaluated. Any hemorrhagic event was recorded by Yellow Card Scheme. Also, the Naranjo scale was utilized for causality assessment.Results: A total of 123 patients were eligible for inclusion. They were admitted between November 2014 and April 2015. Sixty-five patients (52.5%) received heparin and 58 patients (47.2%) received enoxaparin. Of 123 patients, 115 patients (93.5%) received aspirin, 69 (56.1%) warfarin, 34 (27.6%) an antiplatelet medication, and 121 (98.4%) NSAIDs in combination with heparin or enoxaparin. Overall, 26 cases (21.1%) of the hemorrhagic incident were reported, of whom six cases (4.9%) were categorized as major bleeding. Patients receiving heparin constituted the largest proportion among all 26 hemorrhagic incidents (57.7%). All patients with the hemorrhagic incident had aspirin in their medication regimen, while 19 patients (73.0%) were concomitantly receiving warfarin as well. Hematuria (46.2%), hematoma in the injection site (38.5%), and hematoma (34.6%) were the top three types of hemorrhagic events. In Naranjo scale analysis, 19 patients scored more than 9 points, indicating a definite Adverse Drug Reaction (ADR) causality. Moreover, seven patients scored 5 to 8, affirming a possible association with ADR.
Conclusion: The risk of hemorrhagic can be influenced by undesirable drug-drug interactions. Close monitoring of high-risk patients is advised to prevent adverse hemorrhagic reactions. Further studies to detect the explanatory factors associated with the hemorrhagic events are recommended.
Synthesis of Pyrazolo[1,2-b]phthalazine-5,10- dione Derivatives: A New Class of α –Glucosidase Inhibitors
Authors: Hosseinpoor Tehrani Maryam , Mirshokraie Seyed Ahmad , Khoobi Mehdi , Amini Mohsen
Published: November 2021

Background: Hyperglycemia is a metabolic disorder that refers to an increase in blood sugar in diabetic patients. α-Glucosidase has been introduced as a membrane-bound enzyme, and it is the main enzyme for carbohydrate digestion in some parts of the intestine. Inhibition of α -glucosidase enzyme activity is a reliable approach to control post-prandial hyperglycemia condition.
Objectives: In this study, a series of Pyrazolo[1,2-b]phthalazine-5,10-dione derivatives 5a–t were synthesized via a multicomponent reaction and evaluated as new inhibitors for α-glucosidase.
Methods: The biological activity of the synthesized compounds was studied using a source of the α-glucosidase enzyme (EC3.2.1.20, Saccharomyces cerevisiae) at 20 U/mg concentration.
Results: Four compounds showed higher α-glucosidase inhibitory activity in comparison to a standard, i.e., Acarbose. Compound 5q displays the most potent α-glucosidase inhibitory activity (IC50 = 155.4 ± 6.0 μM).
Conclusion: In conclusion, some of the synthesized compounds, including heterocyclic core molecules, have shown remarkable activity that could be considered as subjects for the development of new, more efficient inhibitors of the α-glucosidase enzyme.
Clinical Case Series of Gastrointestinal Symptoms in Patients With Novel Coronavirus 2019 Infection
Authors: Abbaspour Kasgari Hamideh , Shabani Amir Mohammad , Fakheri Hafez , Mohammadzadeh Parnian
Published: November 2021

Background: Various digestive symptoms have been frequently reported in a significant portion of patients infected with the virus since the outbreak of Coronavirus Disease 2019 (COVID-19). Most patients with COVID-19 have a fever accompanied by respiratory signs and symptoms, such as cough and dyspnea. We present 36 cases with a chief complaint of Gastrointestinal (GI) symptoms along with respiratory symptoms. In this study, we aimed at investigating the prevalence and outcomes of COVID-19 patients with digestive symptoms.
Methods: A variety of observed GI symptoms included nausea and vomiting (72.2%), diarrhea (25%), abdominal pain (19.4%), loss of appetite (14%), and anosmia (14%). The most nonGI symptoms were dyspnea (66.7%), fever (66.7%), dry cough (58.3%), myalgia (52.4%), and others. Six patients (16.6%) were critically ill, 7 (19.4%) were in stable condition, and 23 patients (64%) showed moderate symptoms. Among the patients, 7 (19.5%) needed critical care and were admitted to ICU. Leucopenia, lymphopenia, and elevated acute-phase proteins were other features observed in these patients. The most common antiviral regimen was hydroxychloroquine and oseltamivir. Finally, 32 patients (89%) were discharged, and 4 (11%) died.
Conclusion: This case series study highlights that patients with COVID-19 are prone to GI symptoms along with fever and respiratory symptoms. Patients may even present with digestive symptoms and without any respiratory symptoms. Hence, clinicians should pay more attention to these patients and help diagnose COVID-19 earlier to start prompt treatment before the occurrence of severe disease.
Association of IRF6 rs2235371 Polymorphism with Non-Syndromic Cleft Lip/Palate: A Meta-analysis
Authors: Neamatzadeh Hossein , Zare-Shehneh Masoud , Mazaheri Mahta , Daliri Karim , Akbarian Elahe , Sheikhpour Elnaz
Published: November 2021

Background: The previous published data on the association between interferon regulatory factor 6 (IRF6) polymorphisms and non-syndromic Cleft Lip/Palate (NSCL ± P) risk remained inconclusive. The aim of this study was to conduct a meta-analysis to further assess the associations.
Methods: A comprehensive search in PubMed, EMBASE, Web of Science, and CNKI for all eligible studies up July 2021.
Results: A total of 23 studies with 6,161 cases and 8,919 controls were selected for this meta-analysis. Overall pooled analysis suggest a significant association between IRF6 rs2235371 polymorphism and CL±P risk under all the five genetic models, i.e., allele (A vs. G: OR=0.754, 95% CI 0.628-0.905, P=0.002), homozygote (AA vs. GG: OR=0.621 95% 0.405-0.953, P=0.029), heterozygote (AC vs. GG: OR=0.619, 95% CI 0.485-0.791, P≤0.001), dominant (AA+AG vs. GG: OR=0.550, 95% CI 0.381-0.794, P=0.001) and recessive model (AA vs. AG+GG: OR=0.583, 95% CI 0.423-0.804, P=0.001). Subgroup analysis by ethnicity showed that rs2235371 was associated with NSCL±P risk in Asians.
Conclusion: This meta-analysis provides strong evidences that IRF6 rs2235371 might be associated with risk of NSCL ± P.
A Meta-Analysis for Prevalence of Cesarean Section, Preterm Birth, Stillbirth, and Low Birth Weight Deliveries in Infected Pregnant Women with COVID-19
Authors: Karimi-Zarchi Mojgan , Schwartz David A. , Dastgheib Seyed Alireza , Bahrami Reza , Javaheri Atiyeh , Emarati Alireza , Asadian Fatemeh , Akbarian Elahe , Neamatzadeh Hossein
Published: November 2021

Background: The aim of this meta-analysis was to estimate the prevalence of cesarean section (CS), preterm birth, stillbirth, and low birth weight deliveries (LBWD) in pregnant women with SARS-COV-2 infection.
Methods: All relevant studies were searched up to 30 February 2021.
Results: A total of 47 studies with 5970 infected pregnant women were included. There were 1010 CS, 55 stillbirths, 524 preterm birth, and 82 with LBWD. Pooled data showed that the prevalence of CS, preterm birth, stillbirth, and LBWD among women with SARS-COV-2 infection was 29.6% (95% CI 0.081-0.160), 2.1% (95% CI 0.081-0.160), 11.5% (95% CI 0.081-0.160), and 2.1% (95% CI 0.081-0.160), respectively. Stratified analysis revealed that these pregnancy outcomes among Asian women were higher than Caucasians.
Conclusion: Our combined data revealed that the CS prevalence (29.6%) was the highest followed by preterm birth (11.5%), stillbirth (2.1%), and LBWD (2.1%) among women with COVID-19.
Prevalence of Urinary Tract Infection in Iranian Newborns with Jaundice: A Meta-Analysis
Authors: Lookzadeh Mohamad Hosein , Bahrami Reza , Ekraminasab Sedigheh
Published: November 2021

Background: Jaundice is the most common clinical problem among newborns. It could be caused by different factors, including infections such as urinary tract infection (UTI). We investigated the prevalence of UTI in Iranian newborns with jaundice and prolonged jaundice in this study based on a larger sample of existing data.
Methods: We searched the databases of PubMed, Web of Sciences, Scopus, CNKI, SciELO, and Google Scholar for English articles, and a search was also done in Persian in Magiran and Scientific Information Database (SID) published until July 2021. Data analysis was performed by Comprehensive Meta-Analysis (CMA) version 2.0 software.
Results: This study included 19 eligible articles out of approximately 240 retrieved articles. The prevalence of UTIs in neonates with jaundice was estimated by pooling the data from 7416 neonates with jaundice. Of those, 369 cases had UTI. Combined data revealed that the prevalence of UTI in neonates with jaundice was 5.4% (95% CI 0.032-0.089, P ≤ 0.001) and there was no publication bias.
Conclusion: The overall prevalence of UTI in Iranian newborns with jaundice was 5.4%. However, more studies with a large sample size are required for better results. Also our review showed a screening of UTI should be considered for infants with jaundice, especially prolonged jaundice.
Death of a 3 Month-Old Infected Infant with Dilated Cardiomyopathy after COVID-19 Infection: A Case Report
Authors: Baghalsafa Fatemeh , Neamatzadeh Hossein , Ekraminasab Sedigheh
Published: November 2021

Background: Several numbers of studies have reported that coronavirus disease-2019 (COVID-19) in infants and children have shown milder symptoms and a better prognosis than in adult patients. However, there is no sufficient evidence on the effect of cardiovascular involvement in COVID-19 in the infant.
Case Report: Here, we report an infant infected with COVID-19 with the manifestations of dilated myocarditis. The patient was referred to Pediatric Emergency with lethargy and tachypnea. On physical examination, she had holosystolic murmur with grade 3/6. The laboratory examinations showed anemia as well as increased alkaline phosphatase (ALP) levels. Due to respiratory distress, she was intubated and put under mechanical ventilation. The diagnosis of COVID-19 infection was confirmed by real-time polymerase chain reaction (RT-PCR) using a pharyngeal specimen. Finally, dilated cardiomyopathy (DCM) was diagnosed and one day after hospitalization the infant was died due to complications of DCM.
Conclusion: It seems that in the infant with severe underlying disease, even a mild COVID-19 infection, may be lethal. Focal viral myocarditis is a very rare condition described by localized disturbance of the myocardium occurring in ventricular dysfunction with significant morbidity and mortality. Thus, due to the possibility of cardiac injury in infected neonates with COVID-19 disease and the manifestation of myocarditis, effective measurement is recommended.
Intracardiac Thrombosis in A Neonate: A Case Report
Authors: Mirjalili Seyed Reza , Danaeian Morteza , Baghalsafa Fatemeh
Published: November 2021

Background: Life-threatening intracardiac thrombosis is rare. Intracardiac thrombosis may affect neonates from the first months of life. Because of the potential risk of serious bleeding, the use of recombinant plasminogen activator (rt-PA) in neonates along with heparin is controversial.
Case Report: We reported a 37- day- old term infant presented with fever, restlessness, malaise, and respiratory acidosis. Right atrial thrombose was identified by ECHO, results of laboratory tests, and examination. She was successfully treated with rt-PA and rivaroxaban.
Conclusion: Early echocardiographic detection before the clot grows large and organized, allows complete, safe, and rapid thrombolysis with rt-PA and rivaroxaban.
Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells
Authors: AKBABA Giray Buğra
Published: November 2021

Cerium(IV) oxide (CeO2) is widely used in industrial fields such as biomedical, glass, electronics, automotive, and pharmacology. In this study, the cytotoxic effects on human peripheral blood cultures of two forms of cerium(IV) oxide with different particle sizes (Bulk-sized Cerium(IV) oxide: BC and Nano-sized Cerium(IV) oxide: NC) in concentrations range of 0.001-200 ppm were investigated. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay were used to determine the cytotoxicity of these forms. According to the test results, it was determined that both forms caused severe cytotoxicity at all concentrations studied. It was observed that cytotoxicity increased with increasing concentration. NCs are more toxic at all concentrations except 100 and 200 ppm concentrations.
Dioxomolybdenum(VI) complexes of ONN chelating thiosemicarbazones: Crystallographic and spectroscopic (UV, IR and NMR) studies
Authors: EĞLENCE BAKIR Songül
Published: November 2021

Four new cis-dioxomolybdenum(VI) complexes of the closed formula [MoO2(L)CH3OH] have been obtained by the condensation of bis(acetylacetonato)dioxomolybdenum(VI) with S-allyl/propyl thiosemicarbazones in methanol. The compounds were identified with elemental analysis, and molecular characterization by UV-Vis, FT-IR, 1H-NMR and 13C-NMR spectroscopies. Also, crystal structures of 1 and 2 were resolved by X-ray diffraction analysis. The single crystal studies indicated a distorted octahedral geometry for complexes. It was noticed that 1 crystallized in the monoclinic P21/c space group with Z=4, while 2 crystallized in tricilinic P-1 space group with Z=2. The O=Mo=O angles of 105.68(8)° (for 1) and 105.96(7)° (for 2) indicated the cis-dioxomolybdenum structure. The spectroscopic and crystallographic studies show that the thiosemicarbazone ligands are bound to cis-MoO22+ moiety as ONN tridentate agent and the 6th coordinated position of the molybdenum is located by the methanol molecule.
Perceptions Of Customs Managers And Agents Towards Import Tax Non- Compliance During Goods Clearing In Malawi
Authors: Chisale Catherine D , Maluwa Alfred
Published: November 2021

Import tax non-compliance is increasing in Malawi. A study was conducted to explore the perceptions of custom managers and agents towards import tax non-compliance with import tax procedures and processes. The design of the study was descriptive and used qualitative data collection and analysis methods. The study was conducted in Malawi’s major border posts of Blantyre and Mwanza in the southern region. A total number of 25 participants were purposively sampled and administered an open-ended data collection tool to collect data using in-depth face-to-face interviews. The qualitative data were analyzed using content analysis. Two themes emerged from the study which were, customs agents' limited knowledge, and corruption. The study results further show that training sessions by the Malawi Revenue Authority created the requisite knowledge to the customs agents which improved import tax compliance. However, corruption needs a long-term solution to change the stakeholders’ mindset. It is recommended that awareness should be created among the stakeholders to change the attitude and perceptions of the Malawian general public towards import tax non-compliance.
Using Differentiation Strategies for Gifted Pupils in Primary School Science Classes
Authors: Letina Alena
Published: November 2021

The aim of this study was to determine the extent to which gifted pupils receive differentiated instruction in primary school science classes, which of the differentiated instruction strategies are used by teachers and how often. The survey sample included 134 primary school teachers. The results show that teachers frequently use questioning and thinking activities but make only minor modifications in the regular curriculum to meet the needs of gifted pupils. Gifted pupils rarely engage in activities such as providing challenges and choices, differentiated reading and writing assignments, individually set work, activities involving curriculum modification, and enrichment centres.
The relation between intercultural Sensitivity and world music preferences Among grammar school and vocational School students
Authors: Petrušić Daniela , Šešelj Tonka
Published: November 2021

The paper explores the influence of the type of secondary education chosen by the participants on the level of intercultural sensitivity and world music preferences, as well as the connection between intercultural sensitivity and world music preferences. The research employed a general data questionnaire, the Intercultural Sensitivity Scale and an assessment scale to examine music fragment preferences in a sample of 124 participants. The results have significant implications for music and pedagogical theory and practice, in terms of increasing intercultural sensitivity and the tolerance of students towards members of other cultures and their music.
Pomen uzaveščanja narečnega besedja pri učečih se
Authors: Valh Lopert Alenka
Published: November 2021

The Dictionary of Standard Slovenian Language (SSKJ 2014) uses seven types of labels (qualifiers). The present article focuses on the style-genre label nar. (dialectal), further specified as vzhodno (eastern). There are 414 entries so labelled in the SSKJ2. This survey will focus on verbs only (98), labelled as dialectal eastern in the SSKJ2, comparing them to those found in Rajh’s material for his dialectal dictionary of Prlekija dialect Gúčati po antùjoško (2010), as well as in The Slovenian Orthography (Slovenski pravopis – SP 2001). The aim is to point out the importance of incorporating the current dialectal vocabulary into the normative manuals, as well as the importance of their labelling being a great help for teachers, language editors, translators, etc.
Predisposition Towards Sustainable Behaviour Among Students in the Pre-school Education Study Programme
Authors: Šindić Aleksandra , Barbarev Kiril , Gavriloski Marko , Lepičnik Vodopivec Jurka
Published: November 2021

Starting from the importance of sustainable behaviour among educators for sustainability in kindergarten, the aim of this empirical quantitative study was to investigate the prevalence of predispositions towards sustainable behaviour among students from the first cycle of the Preschool Education study programme at three universities. The connection between predispositions, the existence of a difference between cognitive and non-cognitive predispositions, and the absence of a statistically significant difference between the predispositions of the students in relation to home faculty and place of residence were determined.
Mnenje vzgojiteljic in vzgojiteljev o kompetentnosti za vodenje gibalnih dejavnosti predšolskih otrok, upoštevajoč lastno gibalno dejavnost
Authors: Plevnik Matej
Published: November 2021

The purpose of the study was to determine whether the regular leisure-time physical activity of preschool teachers (n = 177) is associated with their self-perceived competence for leading physical activities among preschool children. For the data collection on self-assessed physical activity and the subjective assessment of competence for leading the process of physical activities among preschool children, we used a questionnaire. We can conclude that the leisure-time physical activity of preschool teachers is associated with their subjective perception of competence for leading the process of physical activity among preschool children.
The Meaning of Radicalisation in Modern Social Pedagogy
Authors: Bogdan Zupančič Ana
Published: November 2021

The article defines radicalisation as part of the processes of modern liberation, which are recognised in the interlacement of emancipatory potential in social pedagogy and mobilisation in the theory of community development. In parallel to this, we problematise the internally divided socio-pedagogical attitude, which, on the one hand, seeks to liberate, and on the other hand, is repeatedly caught in the preservation of existing
“oppressive” power relations. In doing so, we consider the concerns regarding political action as the goal of “radicalising” social pedagogy, which indicate that in social pedagogy we have internalized collaboration as a democratic “norm” of solving social and other societal issues and thus accepted it as the only formally realistic option to achieve structural change.
Survival Camps in Nature as a Form of Social Skills Training
Authors: Vukovič Matej
Published: November 2021

This paper presents survival camps in nature as a form of social skills training. The camps are aimed primarily at adolescents with behavioural and emotional difficulties. They comprise many everyday social skills where both the group and the individual in the group are important. Social skills are among the many skills we teach in survival camps. Participants become acquainted with the content, methods and skills, and they strengthen the competences that help them to better integrate and function in the society. We shall present to what extent and in what way the social skills of young people are strengthened at survival camps, how young people gain vital experiences and competences and develop their potential.
Crisis Situations Among Children/Adolescents with Emotional and Behavioural Disorders in Education
Authors: Vrhunc Pfeifer Katja
Published: November 2021

Employees in education, especially in residential treatment centres, face crisis situations as a result of emotional and behavioural problems/disorders of children and adolescents. They most often face various types of violence, self-aggression, use of illicit substances and abuse. Cases of children and adolescents with mental health problems are frequent. Crisis interventions differ with the complexity of the situation, and regardless of the approach, an appropriate relationship is crucial to any solution. The purpose of this article is to present and elaborate the most common crisis situations and some successful interventions in such cases.
The Experience of Residential Care from the Perspective of Adolescents and Caregivers
Authors: Gazilj Ivana , Borić Ivana , Ćosić Andrea
Published: November 2021

Aim of the study is to provide an insight into the experience of residential care from the perspective of beneficiaries and experts. The data was collected in two male residential units. The results show that adolescents and caregivers tend to have a negative attitude toward residential care. Adolescents are even more skeptical about the purpose of treatment since they experience shortcomings in the activities and the methods of treatment, as well as monotony and stigmatization by the local community. Caregivers highlight their disappointment regarding the inadequate intervention system and the complexity of working with children with multiple risks and problems.
Flaccid quadriparesis with raised creatine kinase in Guillain-Barré syndrome: a case report with review of literature
Authors: Mahesh Bandari , Pathak Abhishek , Chaurasia Rameshwar Nath , Kumar Anand , Singh Varun Kumar
Published: November 2021

Background: Guillain-Barré syndrome (GBS) is an immune-mediated inflammatory polyneuropathy characterized by acute flaccid paralysis. Elevated creatine kinase (CK) levels in GBS have been reported to be transient, and levels vary from mild to severe. Herein, we report a case of GBS with elevated CK mimicking acute myositis.Case Report: A 48-year-old man presented with pure motor flaccid quadriparesis. Power was 2/5 with hypotonia and areflexia in all four limbs. A nerve conduction study revealed reduced compound muscle action potential in all recorded motor nerves. Serum CK was 2,334 U/L. The patient’s symptoms progressed despite intravenous methylprednisolone administration. Cerebrospinal fluid (day 8) revealed albuminocytological dissociation, and electromyography (day 21) revealed spontaneous activity with neurogenic motor unit action potential suggestive of acute motor axonal neuropathy variant of GBS.Conclusion: In a patient with elevated CK and ascending paralysis, differential diagnosis of GBS should be considered and cerebrospinal fluid study and electromyography should aid in confirming the diagnosis.
​Effect of Hydrilla verticillata in Feed on Production Performance and Carcass Characteristics of Thai Native Chickens
Authors: Boonkeaw P. , Ngampongsai W. , Preuksa N.
Published: November 2021

Background: Producing Thai native chickens through feed commercial is costly. To reduce the cost, native chicken could be fed with local plants or agricultural waste. Hyrrilla verticillate, a dominate macrophyte in Songkhla Lagoon, contain high crude protein and nitrogen free extract. Therefore, this research studied the use of Hydrilla verticillate in Thai native chicken diet on production performance, carcass characteristics and production cost. Methods: The experiment was executed in a completely randomized design (CRD) with 180 one-day-old commercial Thai native chicks. Four dietary treatments supplemented with 0%, 5%, 10% and 15% Hydrilla verticillata were formulated for three different phases of the experimental chickens: starter (1-4 weeks), grower (5-8 weeks) and finisher (9-12 weeks). Two chickens from each replicate were chosen for the carcass characteristics study. Result: During the starter phase, there was no notable effect shown among the chickens fed with the diet containing Hydrilla verticillata in terms of feed intake (FI) and body weight gain (BWG) (P greater than 0.05). The control chickens had best feed conversion ratio (FCR) (P less than 0.05), while the grower and the finisher periods, provided with different levels of Hydrilla verticillata, revealed no apparent differences (P greater than 0.05) concerning FI, BWG and FCR. Considering carcass characteristics, there were significant differences in live weight (LW) (P less than 0.05). But, no significant differences between treatments for hot carcass percentage, pectoralis majors, pectoralis minorstrip, thighs, wings, drumsticks and total edible carcass (P greater than 0.05). There were also statistical divergences regarding gizzard weight (GW) (P less than 0.05).
Estudio morfoagronómico de materiales de cacao (Theobroma cacao L.) de diferentes zonas productoras en Colombia
Authors: López Hernández Martha del Pilar , Sandoval Aldana Angélica Piedad , García Lozano Jairo , Criollo Nuñez Jenifer
Published: November 2021

Las características de los productos agrícolas están influenciadas por el ecosistema desde la perspectiva de los factores bióticos y abióticos, lo cuales producen en la planta respuestas fisiológicas y a su vez en los frutos propiedades fisicoquímicas únicas, que son la base para las denominaciones de origen y estrategias de agregación de valor al producto en el mercado actual. En el presente trabajo se caracterizaron morfoagronómicamente diez materiales de cacao (Theobroma cacao L.) que fueron seleccionados por su destacada productividad (FSV41, FLE3, FEAR5, FSA12, FEC2, SCC23, SCC80, SCC55, ICS95 y CCN51), los cuales fueron establecidos en departamentos como Santander (931 m s. n. m.), Huila (885 m s. n. m.) y Arauca (204 m s. n. m.), principales zonas productoras de cacao en Colombia. Para la evaluación de las características físicas de materiales recolectados se utilizaron 21 descriptores cuantitativos encargados de definir la variabilidad física del fruto según el clon y el lugar donde se recolecto. Los datos recolectados fueron analizados mediante la matriz de correlación de Pearson y análisis de componentes principales, logrando identificar aquellos descriptores que más aportan a la variabilidad entre materiales (índice de mazorca, relación longitud diámetro, peso y diámetro de semilla y peso y longitud de fruto). Además, se pudo comprobar el efecto del lugar de cosecha sobre las características físicas de los materiales resaltando la importancia del estudio de adaptación previo a la siembra del material de cacao, con el objetivo de garantizar una cosecha de cacao Premium, productiva y de calidad para la industria, que compita en el mercado.
Distribución de fotoasimilados en los órganos vertederos de plantas Solanaceas, caso tomate y papa. Una revisión
Authors: León-Burgos Andres Felipe , Beltrán Cortes Gina Yuret , Barragán Pérez Andrea Liliana , Balaguera-López Helber Enrique
Published: November 2021

Los cultivos de tomate y papa son productos agrícolas de gran importancia a nivel mundial por su valor nutricional e industrial. La distribución de fotoasimilados en los órganos vertederos de estos cultivos depende en gran medida del metabolismo y partición de carbono generado en los procesos fotosintéticos, en la dinámica tanto de los órganos fuente y vertedero como en la actividad de enzimas vinculadas al metabolismo de azúcares, así como factores ambientales y nutricionales. Basado en esto, el objetivo de este documento fue revisar y discutir sobre el conocimiento actual de la distribución de los fotoasimilados en los órganos vertederos y los factores que pueden afectar este mecanismo en los cultivos de tomate y papa. De acuerdo con la información recopilada en artículos de investigación y de revisión recientes, se reporta que alrededor del 80% o 90% de los fotoasimilados producidos en los órganos fuentes en los cultivos de tomate y papa son transportados o translocados hacia los órganos vertederos de interés comercial (frutos y tubérculos). Tanto el desbalance en fuente/vertedero, así como el estrés hídrico y nutricional, en especial, deficiencias de nitrógeno y potasio afectan significativamente la distribución y transporte de los fotoasimilados. En contraste con los efectos de la calidad de la luz puede mejorar la carga de fotoasimilados en los órganos vertederos y mejorar atributos de la calidad como aumento en el tamaño de los frutos y concentración de azucares. Sin embargo, aún faltan más investigaciones que corrobore este efecto bajo condiciones de campo o en invernadero en las condiciones del trópico.
Lessons from K-12 Education in Asia-Pacific Countries Successful in the PISA: ICT Integration Dimension
Authors: FİŞ ERÜMİT Semra , KELEŞ Esra
Published: November 2021

This research aims to examine the integration of Information and Communication Technologies (ICT) into the instructional settings in Asia-Pacific countries and states, ranking among the Top 10 in the PISA test. PISA is an OECD’s assessment tool which is applied every three years to measure 15-year-olds’ ability to use their knowledge in mathematics, science, and reading. PISA was first held in 2000, and it has been observed an increasing number of Asia-Pacific countries and states in the Top 10 over the years. Nowadays, one focus of national education systems is on educational technologies and their impact on teaching processes. Therefore, this study focuses on studies regarding the ICT integration of countries in the Asia-Pacific region and their effects on student performance in the PISA test. The document analysis method was used to examine PISA results and reports, OECD reports, ICT integration projects, and studies on PISA. Successful ICT integration activities of Asia-Pacific countries and states were determined by comparing their efforts for ICT integration across countries. Additionally, studies on ICT integration of the Asia-Pacific countries were compared with the studies conducted in Turkey and inferences were made about the effect of ICT integration studies on the outcomes of PISA.
Open Archival Information System
Authors: Santos Henrique Machado dos , Flores Daniel
Published: November 2021

Objetivo: analisar as entidades funcionais do Open Archival Information System (OAIS), e apontar convergências com a Arquivística, tendo em vista a implementação de um Repositório Arquivístico Digital Confiável (RDC-Arq). Metodologia: artigo de revisão assistemática/narrativa que parte do levantamento bibliográfico de materiais previamente publicados, composto por livros, normas técnicas e artigos científicos recuperados pela ferramenta Google Scholar e pela Base de Dados em Ciência da Informação. Resultados: o modelo funcional proposto pelo OAIS permite receber, gerenciar e disseminar documentos arquivísticos digitais. Seus fluxos de informação são registrados e garantem a manutenção da autenticidade frente às ações realizadas no âmbito do RDC-Arq, como migrações e acréscimos de informações necessárias à preservação. Esse modelo funcional atende questões essenciais como negociar aquisições, transferências e recolhimento com produtores e custodiadores, além de gerenciar as demandas dos consumidores. Conclusões: o modelo funcional OAIS possibilita receber a documentação de forma adequada, adicionar as informações descritivas necessárias, armazenar os documentos de forma segura, gerenciar políticas de preservação e facilitar a disseminação à comunidade designada. Ademais, poderá ser incorporado ao sistema de arquivos, sendo base para implementar o RDC-Arq, e assim, proteger a custódia e garantir o acesso contínuo à documentos digitais autênticos no longo prazo.
Contribution of Satellite Campuses Financial Accountability and Resource Allocation on Financial Sustainability of Public Universities in Kenya
Authors: Musiega Maniagi , Rading Jared G.O.O , Oruko Fredrick
Published: November 2021

This study sought to determine the contributions of satellite campuses on financial sustainability of public universities in Kenya. The specific objectives will be to examine how financial accountability and effective management contribute to financial sustainability of public universities in Kenya. The study adopted descriptive survey research design. The target population was 176 selected staff of public universities in Kenya of which all of them were used in the study. The study adopted both descriptive analysis and for inferential statistical analysis data was cleaned coded and correlation analyses done the findings were financial accountability was positively correlated and significant p< 0.0. For regression also financial accountability as well as resource allocation and effective management had a positive relationship with financial sustainability. R squared was 0.731 therefore financial accountability and resource allocation explained 73.1% of variance in financial sustainability. Moderation was established using hierarchical regression, when the interaction terms of the moderator were added the value of R squared changed from 73.1% to 79.4% thus effective management and leadership had moderating effects on the relationship between financial sustainability and contribution of satellite campuses.Thus universities should mobilize resources from development partners and  focus on recovering full economic costs and investing in its infrastructure including human, intellectual and physical adequately to maintain future productive capacity to deliver its strategic plan and serve its customers.
Earnings Response Coefficient, Sharia Online Trading System, and Firm Value
Authors: Frihatni Andi Ayu , Amiruddin Amiruddin , Darmawati Darmawati , Abbas Ahmad
Published: November 2021

This research aims to examine the nexus between Earnings Response Coefficient (ERC), Sharia Online Trading System (SOTS), and firm value. The research sample was all companies listed on the Jakarta Islamic Index (JII). The research model used path analysis employing the regression with common, fixed and random effect models as well as the robustness check through Generalized Method of Moment (GMM). The result demonstrates that ERC and SOTS can’t determine the level of firm values. This research found no effects of ERC and SOTS on firm value, but nexus between ERC and SOTS was found. These findings indicate that ERC and SOTS have no effect at all on the firm value, meanwhile ERC has the negative effect on SOTS. Nevertheless, the result of this research found no intervening effect of SOTS on the ERC and firm Value. It shows that SOTS can’t mediate the nexus between ERC and firm value.