bluuebunny/crossref_metadata_2025 huggingface dataset:
Bidirectional Ductal Shunting and Preductal to Postductal Oxygenation Gradient in Persistent Pulmonary Hypertension of the Newborn
Authors: Lesneski Amy , Hardie Morgan , Ferrier William , Lakshminrusimha Satyan , Vali Payam
Published: September 2020

Background: The aim was to evaluate the relationship between the direction of the patent ductus arteriosus (PDA) shunt and the pre- and postductal gradient for arterial blood gas (ABG) parameters in a lamb model of meconium aspiration syndrome (MAS) with persistent pulmonary hypertension of the newborn (PPHN). Methods: PPHN was induced by intermittent umbilical cord occlusion and the aspiration of meconium through the tracheal tube. After delivery, 13 lambs were ventilated and simultaneous 129 pairs of pre- and postductal ABG were drawn (right carotid and umbilical artery, respectively) while recording the PDA and the carotid and pulmonary blood flow. Results: Meconium aspiration resulted in hypoxemia. The bidirectional ductal shunt had a lower postductal partial arterial oxygen tension ([PaO2] with lower PaO2/FiO2 ratio—97 ± 36 vs. 130 ± 65 mmHg) and left pulmonary flow (81 ± 52 vs. 133 ± 82 mL/kg/min). However, 56% of the samples with a bidirectional shunt had a pre- and postductal saturation gradient of < 3%. Conclusions: The presence of a bidirectional ductal shunt is associated with hypoxemia and low pulmonary blood flow. The absence of a pre- and postductal saturation difference is frequently observed with bidirectional right-to-left shunting through the PDA, and does not exclude a diagnosis of PPHN in this model.
Class Conflict: Diffuse Competition between Mammalian and Reptilian Predators
Authors: Dickman Christopher R. , Greenville Aaron C. , Wardle Glenda M. , Bytheway Jenna P.
Published: September 2020

(1) Diffuse competition affects per capita rates of population increase among species that exploit similar resources, and thus can be an important structuring force in ecological communities. Diffuse competition has traditionally been studied within taxonomically similar groups, although distantly related intraguild species are likely also to compete to some degree. (2) We assessed diffuse competition between mammalian and reptilian predators at sites in central Australia over 24 years. Specifically, we investigated the effect of dasyurid marsupial abundance on the diet breadth of three groups of lizards (nocturnal dietary generalists, diurnal dietary generalists and dietary specialists). (3) Nocturnal generalist lizards had progressively narrower diets as dasyurid abundance increased. The diet breadth of diurnal generalist lizards was unaffected by overall dasyurid abundance, but was restricted by that of the largest dasyurid species (Dasycercus blythi). Ant- and termite-specialist lizards were unaffected by dasyurid abundance. (4) Diffuse competition, mediated by interference, between dasyurids and nocturnal generalist lizards appears to have strong effects on these lizards, and is the first such between-class interaction to be described. Diffuse interactions may be widespread in natural communities, and merit further investigation among other disparate taxon groups that occur in the same ecological guilds.
Predictive Controller Design for a Cement Ball Mill Grinding Process under Larger Heterogeneities in Clinker Using State-Space Models
Authors: Venkatesh Sivanandam , Ramkumar Kannan , Amirtharajan Rengarajan
Published: September 2020

Chemical process industries are running under severe constraints, and it is essential to maintain the end-product quality under disturbances. Maintaining the product quality in the cement grinding process in the presence of clinker heterogeneity is a challenging task. The model predictive controller (MPC) poses a viable solution to handle the variability. This paper addresses the design of predictive controller for the cement grinding process using the state-space model and the implementation of this industrially prevalent predictive controller in a real-time cement plant simulator. The real-time simulator provides a realistic environment for testing the controllers. Both the designed state-space predictive controller (SSMPC) in this work and the generalised predictive controller (GPC) are tested in an industrially recognized real-time simulator ECS/CEMulator available at FLSmidthPvt. Ltd., Chennai, by introducing a grindability factor from 33 to 27 (the lower the grindability factor, the harder the clinker) to the clinkers. Both the predictive controllers can maintain product quality for the hardest clinkers, whereas the existing controller maintains the product quality only up to the grindability factor of 30.
Current Methods for Body Fluid Identification Related to Sexual Crime: Focusing on Saliva, Semen, and Vaginal Fluid
Authors: Sakurada Koichi , Watanabe Ken , Akutsu Tomoko
Published: September 2020

Although, DNA typing plays a decisive role in the identification of persons from blood and body fluid stains in criminal investigations, clarifying the origin of extracted DNA has also been considered an essential task in proving a criminal act. This review introduces the importance of developing precise methods for body fluid identification. Body fluid identification has long relied on enzymatic methods as a presumptive assay and histological or serological methods as a confirmatory assay. However, because the latest DNA typing methods can rapidly obtain results from very small and even old, poorly preserved samples, the development of a novel corresponding body fluid identification method is required. In particular, an immunochromatographic method has been introduced to identify saliva and semen from sexual crimes. In addition, for vaginal fluid identification, attempts have been made in the past decade to introduce a method relying on body fluid-specific mRNA expression levels. At present, the development of molecular biological methods involving microRNA, DNA methylation, and resident bacterial DNA is ongoing. Therefore, in criminal investigations, body fluid identification is an essential task for correctly applying the results of DNA typing, although further research and development are required.
Both Autopsy and Computed Tomography Are Necessary for Accurately Detecting Rib Fractures Due to Cardiopulmonary Resuscitation
Authors: Hamanaka Kunio , Nishiyama Kei , Nakamura Mami , Takaso Marin , Hitosugi Masahito
Published: September 2020

Few studies have compared the sensitivities of autopsy and post mortem computed tomography (PMCT) in detecting rib fractures caused by cardiopulmonary resuscitation (CPR). We aimed to compare the characteristics between both modalities for accurately detecting CPR-related rib fractures. This single-centre observational study included adult patients with autopsy records and PMCT scans at our institution from January 2013 to March 2019. CPR-related rib fractures were evaluated using autopsy and PMCT findings. In 62 patients enrolled, 339 rib fractures were detected on autopsy and/or PMCT (222 fractures on both PMCT and autopsy, 69 on PMCT alone, and 50 on autopsy alone). The agreement of detection for both modalities was substantial (kappa coefficient, 0.78). In the logistic regression model, incomplete fractures detected by PMCT and age <75 years were significantly associated with findings that were negative on autopsy but positive on PMCT, while rib number (ribs 1–3 and 7–12) and fracture location (posterolateral and paravertebral) were significantly associated with negative PMCT findings but positive autopsy findings. Autopsy and PMCT showed complementary roles, and are thus necessary in accurately detecting CPR-related rib fractures. Combining both modalities may contribute to improved CPR quality and better understanding of discrepancy in characteristics between the two modalities.
Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors
Authors: Althumairy Duaa , Zhang Xiaoping , Baez Nicholas , Barisas George , Roess Deborah A. , Bousfield George R. , Crans Debbie C.
Published: September 2020

Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings. Both receptors and the thyroid-stimulating hormone receptor are members of a subset of G-protein coupled receptors (GPCRs) described as the glycoprotein hormone receptors. Their ligands, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and a structurally related hormone produced in pregnancy, human chorionic gonadotropin (hCG), are large protein hormones that are extensively glycosylated. Although the primary physiologic functions of these receptors are in ovarian function and maintenance of pregnancy in human females and spermatogenesis in males, there are reports of LHRs or FSHRs involvement in disease processes both in the reproductive system and elsewhere. In this review, we evaluate the aggregation state of the structure of actively signaling LHRs or FSHRs, their functions in reproduction as well as summarizing disease processes related to receptor mutations affecting receptor function or expression in reproductive and non-reproductive tissues. We will also present novel strategies for either increasing or reducing the activity of LHRs signaling. Such approaches to modify signaling by glycoprotein receptors may prove advantageous in treating diseases relating to LHRs or FSHRs function in addition to furthering the identification of new strategies for modulating GPCR signaling.
Concept Map and Knowledge
Authors: Ullah AMM Sharif
Published: September 2020

Based on Piaget’s genetic epistemology, Ausubel developed the assimilation theory of verbal learning [...]
Developing a Motion Infographic-Based Learning System for Effective Learning
Authors: Tsai Shih-Ting , Huang Hsin-Yi , Chang Teng-Wen
Published: September 2020

The motion infographic system combines the characteristics of continuous images and the simplification of information, which can make up for the disadvantages of content in static images, and may have the advantage of deepening the impression of infographics. As Taiwan’s elementary school resource classes (elementary school pupils with mild disabilities or learning challenges) do not yet have exclusive learning content, resource class teachers prepare their own teaching content, but they cannot integrate existing learning lists and network resources. Therefore, this study designed and developed a motion infographic system to assist with resource class learning. The theme of this motion infographic system uses a very rare natural phenomenon in Taiwan, the Arctic oscillation, which in early 2016 brought to Taiwan the lowest recorded temperature on the flat ground. The study analyzed the learning effectiveness of this system applied to resource classes through an experimental and control group. The final result shows that the motion infographic system was different from the original content used in the resource class. The improvement in the academic achievement and the grasp of the image shapes of the experimental group was better than the control group, which verified that the motion infographic system can improve learning outcomes in a resource class.
Me and My New World: Effects of a School Based Social-Emotional Learning Program for Adolescents in Panama
Authors: Araúz Ledezma Ana Belinda , Massar Karlijn , Kok Gerjo
Published: September 2020

Gender inequalities still affect the health and well-being of young people worldwide. Given the apprehensions among government and educators in a conservative context like Panama to implement comprehensive sexual education, there is a need for other educational efforts to stimulate healthy and respectful intimate relationships between adolescents. This article examines to what extent a newly developed Social-Emotional Learning (SEL) program, Me and My New World, provides a context in which students can learn to recognize and manage emotions, to care about others and themselves, make responsible decisions, develop social awareness. The program could additionally facilitate behavioral changes of young people towards more gender equality. Specifically, we focused on equal gender roles, equal rights in relationships and nonviolent problem solving, and present the qualitative effect evaluation among adolescents in Panama. The findings suggest that SEL-based lessons might broaden views on how young people experience the process of exploring identity formation, how assumptions of inequalities can be recreated through the lessons, and that SEL can emphasize the significance of choice and decision-making in interpersonal relationships. The perspectives, needs, and limitations highlighted by the adolescents living in a conservative context are highly valuable for improving future learning strategies for the development of healthier relationships.
Experimental Study of Macro Fiber Composite-Magnet Energy Harvester for Self-Powered Active Magnetic Bearing Rotor Vibration Sensor
Authors: Mystkowski Arkadiusz , Ostasevicius Vytautas
Published: September 2020

The paper presents the design, fabrication, and characterization of an energy harvester for an active magnetic bearing (AMB) rotor vibration using a macro fiber composite (MFC) with magnetic coupling. The MFC cantilevers configuration, together with neodymium magnets, is used for the contact-free rotor radial vibration self-powered sensor. The permanent magnets attached to the rotor and to the four MFC element beams ensure the mechanical energy transfer and the MFC cantilever vibration excitation. In the proposed prototype, the MFC transducer output voltage depends on the air-gap between two magnets. This paper investigates the optimum conditions to harvest as much as possible electric energy at different clearances and rotational speeds. Furthermore, to assess the rotor vibration sensitivity, the experimental results of the MFC-magnet self-powered sensor are compared with measurements obtained using a fiber optic sensor. The maximal obtained harvesting power equals 673.47 µW for the rotor speed of 3150 rpm. Moreover, the MFC cantilever was proposed as the rotor vibration sensor. The MFC-magnet self-powered vibration sensor output was compared with the fiber optic laser sensor. The mismatched vibration amplitude for both sensors does not exceed 1 µm.
A Long-Term Condition Monitoring and Performance Assessment of Grid Connected PV Power Plant with High Power Sizing Factor under Partial Shading Conditions
Authors: Corba Zoltan , Popadic Bane , Milicevic Dragan , Dumnic Boris , Katic Vladimir A.
Published: September 2020

Partial shading conditions of photovoltaic (PV) modules often occurs in urban areas leading to losses in electricity power generation of the PV power plant. The purpose of this study is to present how the PV power plant with high value of inverter power sizing factor (Kinv) can achieve high performance and power production under partial shading conditions with high shading losses. In this paper the results of long-term monitoring, performance analysis and experimental results are presented, while the results are compared to the estimated values calculated using PVsyst software. The study focused on the PV power plant at the Faculty of Technical Sciences (FTS) in Novi Sad, Republic of Serbia, for the period between the years 2012 and 2019. It has been shown that the values of PV power plant performance parameters are better than expected (very high), and resemble the power plants operating without shading. The high value of the inverter power sizing factor may lead to occasional saturation of the inverter when certain conditions are met, but most of the times it allows the inverter to operate at a more optimal power level. PV module soiling and power degradation is within the limits mentioned in the literature. The increase in Kinv in the partial shading conditions favorably affects the performance, does not degrade the efficiency of the inverter at saturation, reduces the effect of soiling and aging of PV modules, leading to higher power production.
Application of Photovoltaic Systems for Agriculture: A Study on the Relationship between Power Generation and Farming for the Improvement of Photovoltaic Applications in Agriculture
Authors: Cho Jaiyoung , Park Sung Min , Park A Reum , Lee On Chan , Nam Geemoon , Ra In-Ho
Published: September 2020

Agrivoltaic (agriculture–photovoltaic) or solar sharing has gained growing recognition as a promising means of integrating agriculture and solar-energy harvesting. Although this field offers great potential, data on the impact on crop growth and development are insufficient. As such, this study examines the impact of agriculture–photovoltaic farming on crops using energy information and communications technology (ICT). The researched crops were grapes, cultivated land was divided into six sections, photovoltaic panels were installed in three test areas, and not installed in the other three. A 1300 × 520 mm photovoltaic module was installed on a screen that was designed with a shading rate of 30%. In addition, to collect farming-cultivation-environment data and to analyze power generation, sensors for growing environments and wireless-communication devices were used. As a result, normal modules generated 25.2 MWh, bifacial modules generated 21.6 MWh, and transparent modules generated 25.7 MWh over a five-month period. We could not find a difference in grape growth according to the difference of each module. However, a slight slowing of grape growth was found in the experiment group compared to the control group. Nevertheless, the sugar content of the test area of the grape fruit in the harvest season was 17.6 Brix on average, and the sugar content of the control area was measured at 17.2 Brix. Grape sugar-content level was shown to be at almost the same level as that in the control group by delaying the harvest time by about 10 days. In conclusion, this study shows that it is possible to produce renewable energy without any meaningful negative impact on normal grape farming.
State-Space Modeling Techniques of Emerging Grid-Connected Converters
Authors: Mandrile Fabio , Musumeci Salvatore , Carpaneto Enrico , Bojoi Radu , Dragičević Tomislav , Blaabjerg Frede
Published: September 2020

In modern power electronics-based power systems, accurate modeling is necessary in order to analyze stability and the interaction between the different elements, which are connected to it. State space modeling seems a valid approach to study the modes of a certain system and their correlation with its states. Unfortunately, this approach may require complicated calculations and it is difficult to model advanced or emerging control techniques for grid-tied converters, such as cascaded controllers (e.g., voltage and current) and virtual synchronous generators (VSGs). Moreover, this approach does not allow an easy reconfiguration of the modeled system by adding, removing of modifying certain elements. To solve such problems, this paper presents a step-by-step approach to the converter modeling based on the Component Connection Method (CCM). The CCM is explained in detail and a practical example is given, by modeling one exemplary VSG model available in the literature. The obtained model is finally validated experimentally to demonstrate the practical accuracy of such approach.
Effects of Ball Milling and TiF3 Addition on the Dehydrogenation Temperature of Ca(BH4)2 Polymorphs
Authors: Llamas Jansa Isabel , Friedrichs Oliver , Fichtner Maximilian , Bardají Elisa Gil , Züttel Andreas , Hauback Bjørn C.
Published: September 2020

The changes introduced by both ball milling and the addition of small amounts of TiF3 in the kinetics of the hydrogen desorption of three different Ca(BH4)2 polymorphs (α, β and γ) have been systematically investigated. The samples with different polymorphic contents, before and after the addition of TiF3, were characterized by powder X-ray diffraction and vibrational spectroscopy. The hydrogen desorption reaction pathways were monitored by differential scanning calorimetry. The hydrogen desorption of Ca(BH4)2 depends strongly on the amount of coexistent α, β and γ polymorphs as well as additional ball milling and added TiF3 to the sample. The addition of TiF3 increased the hydrogen desorption rate without significant dissociation of the fluoride. The combination of an α-Ca(BH4)2 rich sample with 10 mol% of TiF3 and 8 h of milling led to up to 27 °C decrease of the hydrogen desorption peak temperature.
Modeling Wildland Firefighter Travel Rates by Terrain Slope: Results from GPS-Tracking of Type 1 Crew Movement
Authors: Sullivan Patrick R. , Campbell Michael J. , Dennison Philip E. , Brewer Simon C. , Butler Bret W.
Published: September 2020

Escape routes keep firefighters safe by providing efficient evacuation pathways from the fire line to safety zones. Effectively utilizing escape routes requires a precise understanding of how much time it will take firefighters to traverse them. To improve this understanding, we collected GPS-tracked travel rate data from US Interagency Hotshot “Type 1” Crews during training in 2019. Firefighters were tracked while hiking, carrying standard loads (e.g., packs, tools, etc.) along trails with a precisely-measured terrain slope derived from airborne lidar. The effects of the slope on the instantaneous travel rate were assessed by three models generated using non-linear quantile regression, representing low (bottom third), moderate (middle third), and high (upper third) rates of travel, which were validated using k-fold cross-validation. The models peak at about a −3° (downhill) slope, similar to previous slope-dependent travel rate functions. The moderate firefighter travel rate model mostly predicts faster movement than previous slope-dependent travel rate functions, suggesting that firefighters generally move faster than non-firefighting personnel while hiking. Steepness was also found to have a smaller effect on firefighter travel rates than previously predicted. The travel rate functions produced by this study provide guidelines for firefighter escape route travel rates and allow for more accurate and flexible wildland firefighting safety planning.
Assessment of the Prevalence and Drug Susceptibility of Listeria monocytogenes Strains Isolated from Various Types of Meat
Authors: Skowron Krzysztof , Wałecka-Zacharska Ewa , Wiktorczyk-Kapischke Natalia , Skowron Karolina Jadwiga , Grudlewska-Buda Katarzyna , Bauza-Kaszewska Justyna , Bernaciak Zuzanna , Borkowski Miłosz , Gospodarek-Komkowska Eugenia
Published: September 2020

Listeria monocytogenes are the etiological factor of listeriosis, and their main source for humans is food. The aim of the current study was to assess the contamination of various types of meat and the drug susceptibility of isolated L. monocytogenes. Between 2016–2018, 6000 swabs were taken (2000 annually) from the surface of pork, beef, and poultry. The analysis of intermediate and finished product samples was carried out in accordance with ISO 11290-1 (International Organization for Standardization). The genetic similarity assessment of the isolates obtained was based on the Pulsed Field Gel Electrophoresis (PFGE) method, and drug-sensitivity assessment using the disc-diffusion method. We found 2.1% of collected samples were L. monocytogenes positive. The level of meat contamination varied depending on its matrix. Most L. monocytogenes were isolated from poultry. It was shown that 39 (32.5%) strains were sensitive to all tested antibiotics and eight (6.7%) were resistant to all five tested antimicrobials. Most strains tested were resistant to cotrimoxazole (55; 45.8%) and meropenem (52; 43.3%), followed by erythromycin (48; 40.0%), penicillin (31; 25.8%), and ampicillin (21; 17.5%). High prevalence of this pathogen may be a serious problem, especially when linked with antibiotic resistance and high percentage of serotypes responsible for listeriosis outbreaks.
Application of Analytical Chemistry to Foods and Food Technology
Authors: Naviglio Daniele , Gallo Monica
Published: September 2020

Foods are a mixture of substances capable of supplying the human body with nutrients, which, once metabolized, are used mainly for the production of energy, heat, replenishment, and growth material for organs and tissues, ensuring the normal performance of vital functions necessary for growth of the human body. Therefore, the study of the chemical composition of foods and the properties of their constituents helps to define their nutritional and commodity values. Furthermore, it allows for evaluation of the chemical modifications that the constituents of the food undergo following the treatments (Food Technology) to which they are subjected. Analytical chemistry is the branch of chemistry based on the qualitative and quantitative determination of compounds present in a sample under examination. Therefore, through its application, it is possible to determine the quality of a product and/or its nutritional value, reveal adulterations, identify the presence of xenobiotic substances potentially harmful to human health (heavy metals, IPA, pharmaceuticals, etc.). Furthermore, some foods, in particular those of plant origin, contain numerous substances, secondary metabolites, with huge beneficial effects for human health. These functional components can be taken both through a correct diet, but also obtained from different food matrices by technological or biotechnological processes for the formulation of both functional foods and/or nutraceutical products. This Special Issue brings together 10 original studies and two comprehensive reviews on the above topics, in particular: (i) processes of extraction, identification, and characterization of biologically active compounds from different food matrices, (ii) overview of the main techniques applied for the determination of food colors, (iii) newer and greener solid-liquid extraction techniques.
Quality and Nutritional/Textural Properties of Durum Wheat Pasta Enriched with Cricket Powder
Authors: Carcea Marina
Published: September 2020

Edible insects have always been consumed by humans and nowadays they are looked at with interest by the research community as a means to produce food at low environmental cost for a growing and increasingly demanding population. A large number of different species are edible, and they can contribute fats, protein, fibre, vitamins, and minerals to the human diet. The absence of specific legislation on the use of insects as food, coupled with the general population’s disgust at the idea of eating insects, are among the limiting factors for the development of insect farming in developed countries. Several consumer studies have concluded that hiding insects in traditional foods can increase people’s willingness to eat insect-based foods. Cereal-based foods such as bread, bakery products, pasta, etc., being so popular worldwide and so widely accepted by the population, have been used by researchers as a carrier for the introduction of different percentages of insect flours to improve their nutritional qualities. The research by Duda et al. on “Quality and Nutritional/Textural Properties of Durum Wheat Pasta enriched with Cricket Powder” is the first recent scientific contribution to the understanding of the nutritional quality and technological effects of the introduction of insect flour in a popular food such as durum wheat pasta.
Validity of Items Assessing Self-Reported Number of Breaks in Sitting Time among Children and Adolescents
Authors: Van Oeckel Veerle , Deforche Benedicte , Ridgers Nicola D. , Bere Elling , Verloigne Maïté
Published: September 2020

Background: Sedentary behaviour guidelines recommend that individuals should regularly break up sitting time. Accurately monitoring such breaks is needed to inform guidelines concerning how regularly to break up sitting time and to evaluate intervention effects. We investigated the concurrent validity of three “UP4FUN child questionnaire” items assessing the number of breaks in sitting time among children and adolescents. Methods: Fifty-seven children and adolescents self-reported number of breaks from sitting taken at school, while watching TV, and during other screen time activities. Participants also wore an activPAL monitor (PAL Technologies, Glasgow, UK) to objectively assess the number of sitting time breaks (frequency/hour) during the school period and the school-free period (which was divided in the periods “after school” and “during the evening”). Concurrent validity was assessed using Spearman rank correlations. Results: Self-reported number of breaks/hour at school showed good concurrent validity (ρ = 0.676). Results were moderate to good for self-reported number of breaks/hour while watching TV (ρ range for different periods: 0.482 to 0.536) and moderate for self-reported number of breaks/hour in total screen time (ρ range for different periods: 0.377 to 0.468). Poor concurrent validity was found for self-reported number of breaks/hour during other screen time activities (ρ range for different periods: 0.157 to 0.274). Conclusions: Only the questionnaire items about number of breaks at school and while watching TV appear to be acceptable for further use in research focussing on breaks in prolonged sitting among children and adolescents.
Assessment of Active Video Games’ Energy Expenditure in Children with Overweight and Obesity and Differences by Gender
Authors: Comeras-Chueca Cristina , Villalba-Heredia Lorena , Pérez-Llera Marcos , Lozano-Berges Gabriel , Marín-Puyalto Jorge , Vicente-Rodríguez Germán , Matute-Llorente Ángel , Casajús José A. , González-Agüero Alejandro
Published: September 2020

(1) Background: Childhood obesity has become a main global health problem and active video games (AVG) could be used to increase energy expenditure. The aim of this study was to investigate the energy expenditure during an AVG intervention combined with exercise, differentiating by gender. (2) Methods: A total of 45 children with overweight or obesity (19 girls) performed an AVG intervention combined with exercise. The AVG used were the Xbox Kinect, Nintendo Wii, dance mats, BKOOL cycling simulator, and Nintendo Switch. The energy expenditure was estimated from the heart rate recorded during the sessions and the data from the individual maximal tests. (3) Results: The mean energy expenditure was 315.1 kilocalories in a one-hour session. Participants spent the most energy on BKOOL, followed by Ring Fit Adventures, Dance Mats, Xbox Kinect, and the Nintendo Wii, with significant differences between BKOOL and the Nintendo Wii. Significant differences between boys and girls were found, but were partially due to the difference in weight, VO2max, and fat-free mass. (4) Conclusions: The energy expenditure with AVG combined with multi-component exercise was 5.68 kcal/min in boys and 4.66 kcal/min in girls with overweight and obesity. AVG could be an effective strategy to increase energy expenditure in children and adolescents with overweight and obesity.
Sexual Knowledge, Attitudes and Behaviours among Undergraduate Students in China—Implications for Sex Education
Authors: Lyu Jinping , Shen Xiaoyun , Hesketh Therese
Published: September 2020

Background: Despite rapid modernization and improving gender equity in China in recent decades, traditional values prevail in many areas of life, including sexual behavior. This study aimed to explore gender differences in sexual knowledge, sexual attitudes and sexual behaviors, as well as preferences for sex education among undergraduates in China. Methods: A cross-sectional study surveyed 5965 undergraduates (62.8% females), aged 15 to 24 years from nine universities in Zhejiang, Henan and Yunnan provinces, from September to November 2019. Results: Of the total sample, 158 (2.6%) self-identified as homosexual, 287 (4.8%) as bisexual and 324 (5.4%) stated they were unclear about their sexual identity. The mean sexual knowledge score out of 12 was 6.16 ± 2.54 points. Ever having sexual intercourse was reported by 18.7% (27.0% males, and 13.9% females). Students from urban backgrounds, and those with homosexual and bisexual orientation were more likely to have had sexual intercourse. Most students (72.5%) reported that they would prefer to receive sex education from on-line sources. Conclusions: Female students are significantly more conservative in sexual attitudes and sexual behaviors. Low levels of sexual knowledge contribute to risk behaviors among Chinese adolescents. China needs to develop and widely disseminate on-line sex education, with practical, age-appropriate content.
The Quality of Counselling for Oral Emergency Contraceptive Pills—A Simulated Patient Study in German Community Pharmacies
Authors: Langer Bernhard , Grimm Sophia , Lungfiel Gwenda , Mandlmeier Franca , Wenig Vanessa
Published: September 2020

Background: In Germany, there are two different active substances, levonorgestrel (LNG) and ulipristal acetate (UPA), available as emergency contraception (the “morning after pill”) with UPA still effective even 72 to 120 h after unprotected sexual intercourse, unlike LNG. Emergency contraceptive pills have been available without a medical prescription since March 2015 but are still only dispensed by community pharmacies. The aim of this study was to determine the counselling and dispensing behaviour of pharmacy staff and the factors that may influence this behaviour in a scenario that intends that only the emergency contraceptive pill containing the active substance UPA is dispensed (appropriate outcome). Methods: A cross-sectional study was carried out in the form of a covert simulated patient study in a random sample of community pharmacies stratified by location in the German state of Mecklenburg-Vorpommern and reported in accordance with the STROBE statement. Each pharmacy was visited once at random by one of four trained test buyers. They simulated a product-based request for an emergency contraceptive pill, stating contraceptive failure 3.5 days prior as the reason. The test scenario and the evaluation forms are based on the recommended actions, including the checklist from the Federal Chamber of Pharmacies. Results: All 199 planned pharmacy visits were carried out. The appropriate outcome (dispensing of UPA) was achieved in 78.9% of the test purchases (157/199). A significant correlation was identified between the use of the counselling room and the use of a checklist (p < 0.001). The use of a checklist led to a significantly higher questioning score (p < 0.001). In a multivariate binary logistic regression analysis, a higher questioning score (adjusted odds ratio [AOR] = 1.41; 95% CI = 1.22–1.63; p < 0.001) and a time between 12:01 and 4:00 p.m. (AOR = 2.54; 95% CI = 1.13–5.73; p = 0.024) compared to 8:00 to 12:00 a.m. were significantly associated with achieving the appropriate outcome. Conclusions: In a little over one-fifth of all test purchases, the required dispensing of UPA did not occur. The use of a counselling room and a checklist, the use of a checklist and the questioning score as well as the questioning score and achieving the appropriate outcome are all significantly correlated. A target regulation for the use of a counselling room, an explicit guideline recommendation about the use of a checklist, an obligation for keeping UPA in stock and appropriate mandatory continuing education programmes should be considered.
Multidimensional Energy Poverty and Mental Health: Micro-Level Evidence from Ghana
Authors: Lin Boqiang , Okyere Michael Adu
Published: September 2020

Regardless of growing interest and awareness of the effect of energy poverty on mental health, studies on this linkage have mainly relied on unidimensional measures of energy poverty with much concentration on advanced economies. Employing a two-wave socioeconomic survey, we analyzed the impact of multidimensional energy poverty on mental health in Ghana. We found energy poverty to heighten the chances of being mentally unhealthy. Using prices of liquefied petroleum gas and electricity as instruments for multidimensional energy poverty, we found that a rise in energy deprivation is associated with a 0.562-, 1.494- and 1.867-fold increase in the odds of being mildly, moderately and severely depressed, respectively. Among the indicators of multidimensional energy poverty, a deprivation in household appliance ownership (refrigerator ownership), recorded the highest impact on the depression levels of household heads. We concluded by urging policymakers to adopt a holistic approach in solving issues of energy poverty where simultaneous attention is given to all the dimensions of energy poverty since they collectively have detrimental effects on mental health, especially in a developing country setting.
A Critical Review of the Status of Pesticide Exposure Management in Malawi
Authors: Kosamu Ishmael , Kaonga Chikumbusko , Utembe Wells
Published: September 2020

Pesticides pose a significant risk to humans and the environment. This paper analyzes the measures used to manage pesticides in Malawi. Malawi’s regulatory authority of pesticides, the Pesticides Control Board (PCB), faces a number of challenges including lack of facilities for analyzing pesticides and inadequate personnel to conduct risk assessment of pesticides. The PCB needs to provide access to information and opportunities among the public to make contributions regarding requirements, processes and policies for assessing pesticide risk and efficacy. There is also a need to enhance the capacity of PCB to assess pesticide poisoning in workers, monitor pesticide residues in food and environmental contamination, as well as to control the illegal importation and sale of pesticides. Just like in other countries such as South Africa, India and Sri Lanka, Malawi urgently needs to implement measures that can restrict the importation, production, sale and use of very toxic pesticides. Malawi also needs to develop measures for the effective management of pesticide waste containers as well as obsolete pesticides, where potential solutions include reducing the purchase of (unneeded) pesticides, treatment of obsolete pesticides in high-temperature cement kilns, as well as requesting pesticide dealers to adopt life-cycle management of their products.
Assessment and Mapping of Spatio-Temporal Variations in Human Mortality-Related Parameters at European Scale
Authors: Andreopoulos Panagiotis , Polykretis Christos , Tragaki Alexandra
Published: September 2020

Research efforts focusing on better understanding and capture of mortality progression over the time are considered to be of significant interest in the field of demography. On a demographic basis, mortality can be expressed by different physical parameters. The main objective of this study is the assessment and mapping of four such parameters at the European scale, during the time period 1993–2013. Infant mortality (parameter θ), population aging (parameter ξ), and individual and population mortality due to unexpected exogenous factors/events (parameter κ and λ, respectively) are represented from these parameters. Given that their estimation is based on demographics by age and cause of death, and in order to be examined and visualized by gender, time-specific mortality and population demographic data with respect to gender, age, and cause of death was used. The resulting maps present the spatial patterns of the estimated parameters as well as their variations over the examined period for both male and female populations of 22 European countries in all.
Monitoring of Urban Growth Patterns in Rapidly Growing Bahir Dar City of Northwest Ethiopia with 30 year Landsat Imagery Record
Authors: Kindu Mengistie , Angelova Daniela , Schneider Thomas , Döllerer Martin , Teketay Demel , Knoke Thomas
Published: September 2020

Monitoring urban growth patterns is an important measure to improve our understanding of land use/land cover (LULC) changes and a central part in the proper development of any city. In this study, we analyzed the changes over a period of 30 years (1985–2015) in Bahir Dar, one of the rapidly growing cities of northwest Ethiopia. Satellite images of Landsat TM (1985, 1995, and 2008), and OLI (2015) were used. The classification was carried out using the object-based image analysis technique and a change analysis was undertaken using post-classification comparison in GIS as a novel framework. An accuracy assessment was conducted for each reference year. Eight LULC types were successfully captured with overall accuracies ranging from 88.3% to 92.9% and a Kappa statistic of 0.85 to 0.92. The classification result revealed that cropland (66%), water (12.5%), and grassland (6%) were the dominant LULC types with a small share of areas covered by built-up areas (2.4%) in 1985. In 2015, cropland and water continued to be dominant followed by built-up areas. The change result shows that a rapid reduction in natural forest cover followed by grassland and wetland occurred between the first (1985–1995), second (1995–2008), and third (2008–2015) study periods. On the contrary, build-ups increased in all three periods by 9.3%, 121.3%, and 44.8%, respectively. Although the conversion between the LULC classes varied substantially, analysis of the 30-year change matrix revealed that about 31% was subject to intensive change between the classes. Specifically, the built-up area has increased by 250.5% during the study years. The framed approach used in this research is a good repeatable example of how to assess and monitor urban growth at the local level, by combining remote sensing and GIS technologies. Further study is suggested to investigate detailed drivers, consequences of changes, and future options.
Earth Observation and GIS-Based Analysis for Landslide Susceptibility and Risk Assessment
Authors: Psomiadis Emmanouil , Charizopoulos Nikos , Efthimiou Nikolaos , Soulis Konstantinos X. , Charalampopoulos Ioannis
Published: September 2020

Landslides can cause severe problems to the social and economic well-being. In order to effectively mitigate landslide hazards, the development of detailed susceptibility maps is required, towards implementing targeted risk management plans. This study aims to create detailed landslide susceptibility (LS) and landslide risk (LR) maps of the Sperchios River basin by applying an expert semi-quantitative approach that integrates the Geographic Information Systems (GIS)-based multicriteria analysis and Earth Observation (EO) data. Adopting the analytic hierarchy process (AHP) for a weighted linear combination (WLC) approach, eleven evaluation parameters were selected. The results were validated using a historic landslide database, enriched with new landslide locations mapped by satellite and aerial imagery interpretation and field surveys. Moreover, the landslide risk map of the area was also developed, based on the LS delineation, considering additionally the anthropogenic exposure and overall vulnerability of the area. The results showed that the most susceptible areas are located at the west and south-west regions of the basin. The synergistic use of GIS-based analysis and EO data can provide a useful tool for the design of natural hazards prevention policy at highly susceptible to risk landslide risk areas.
AGL15 Controls the Embryogenic Reprogramming of Somatic Cells in Arabidopsis through the Histone Acetylation-Mediated Repression of the miRNA Biogenesis Genes
Authors: Nowak Katarzyna , Morończyk Joanna , Wójcik Anna , Gaj Małgorzata D.
Published: September 2020

The embryogenic transition of somatic cells requires an extensive reprogramming of the cell transcriptome. Relevantly, the extensive modulation of the genes that have a regulatory function, in particular the genes encoding the transcription factors (TFs) and miRNAs, have been indicated as controlling somatic embryogenesis (SE) that is induced in vitro in the somatic cells of plants. Identifying the regulatory relationships between the TFs and miRNAs during SE induction is of central importance for understanding the complex regulatory interplay that fine-tunes a cell transcriptome during the embryogenic transition. Hence, here, we analysed the regulatory relationships between AGL15 (AGAMOUS-LIKE 15) TF and miR156 in an embryogenic culture of Arabidopsis. Both AGL15 and miR156 control SE induction and AGL15 has been reported to target the MIR156 genes in planta. The results showed that AGL15 contributes to the regulation of miR156 in an embryogenic culture at two levels that involve the activation of the MIR156 transcription and the containment of the abundance of mature miR156 by repressing the miRNA biogenesis genes DCL1 (DICER-LIKE1), SERRATE and HEN1 (HUA-ENHANCER1). To repress the miRNA biogenesis genes AGL15 seems to co-operate with the TOPLESS co-repressors (TPL and TPR1-4), which are components of the SIN3/HDAC silencing complex. The impact of TSA (trichostatin A), an inhibitor of the HDAC histone deacetylases, on the expression of the miRNA biogenesis genes together with the ChIP results implies that histone deacetylation is involved in the AGL15-mediated repression of miRNA processing. The results indicate that HDAC6 and HDAC19 histone deacetylases might co-operate with AGL15 in silencing the complex that controls the abundance of miR156 during embryogenic induction. This study provides new evidence about the histone acetylation-mediated control of the miRNA pathways during the embryogenic reprogramming of plant somatic cells and the essential role of AGL15 in this regulatory mechanism.
Introducing the Amphibious Mudskipper Goby as a Unique Model to Evaluate Neuro/Endocrine Regulation of Behaviors Mediated by Buccal Sensation and Corticosteroids
Authors: Katayama Yukitoshi , Saito Kazuhiro , Sakamoto Tatsuya
Published: September 2020

Some fish have acquired the ability to breathe air, but these fish can no longer flush their gills effectively when out of water. Hence, they have developed characteristic means for defense against external stressors, including thirst (osmolarity/ions) and toxicity. Amphibious fish, extant air-breathing fish emerged from water, may serve as models to examine physiological responses to these stressors. Some of these fish, including mudskipper gobies such as Periophthalmodon schlosseri, Boleophthalmus boddarti and our Periophthalmus modestus, display distinct adaptational behaviors to these factors compared with fully aquatic fish. In this review, we introduce the mudskipper goby as a unique model to study the behaviors and the neuro/endocrine mechanisms of behavioral responses to the stressors. Our studies have shown that a local sensation of thirst in the buccal cavity—this being induced by dipsogenic hormones—motivates these fish to move to water through a forebrain response. The corticosteroid system, which is responsive to various stressors, also stimulates migration, possibly via the receptors in the brain. We suggest that such fish are an important model to deepen insights into the stress-related neuro/endocrine-behavioral effects.