bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the Effects of High-Intensity, Intermittent Exercise and Unanticipation on Trunk and Lower Limb Biomechanics During a Side-Cutting Maneuver Using Statistical Parametric Mapping
Authors: Whyte Enda F. , Richter Chris , O'Connor Siobhan , Moran Kieran A.
Published: March 2018

Whyte, EF, Richter, C, O'Connor, S, and Moran, KA. Investigation of the effects of high-intensity, intermittent exercise and unanticipation on trunk and lower limb biomechanics during a side-cutting maneuver using statistical parametric mapping. J Strength Cond Res 32(6): 1583–1593, 2018—Anterior cruciate ligament (ACL) injuries frequently occur during side-cutting maneuvers when fatigued or reacting to the sporting environment. Trunk and hip biomechanics are proposed to influence ACL loading during these activities. However, the effects of fatigue and unanticipation on the biomechanics of the kinetic chain may be limited by traditional discrete point analysis. We recruited 28 male, varsity, Gaelic footballers (21.7 ± 2.2 years; 178.7 ± 14.6 m; 81.8 ± 11.4 kg) to perform anticipated and unanticipated side-cutting maneuvers before and after a high-intensity, intermittent exercise protocol (HIIP). Statistical parametric mapping (repeated-measures analysis of varience) identified differences in phases of trunk and stance leg biomechanics during weight acceptance. Unanticipation resulted in less trunk flexion (p < 0.001) and greater side flexion away from the direction of cut (p < 0.001). This led to smaller (internal) knee flexor and greater (internal) knee extensor (p = 0.002–0.007), hip adductor (p = 0.005), and hip external rotator (p = 0.007) moments. The HIIP resulted in increased trunk flexion (p < 0.001) and side flexion away from the direction of cut (p = 0.038), resulting in smaller (internal) knee extensor moments (p = 0.006). One interaction effect was noted demonstrating greater hip extensor moments in the unanticipated condition post-HIIP (p = 0.025). Results demonstrate that unanticipation resulted in trunk kinematics considered an ACL injury risk factor. A subsequent increase in frontal and transverse plane hip loading and sagittal plane knee loading was observed, which may increase ACL strain. Conversely, HIIP-induced trunk kinematic alterations resulted in reduced sagittal plane knee and subsequent ACL loading. Therefore, adequate hip and knee control is important during unanticipated side-cutting maneuvers.
Relationship among Market Value Added, Cash Value Added, and Corporate Governance: A Case of Taiwan during 2011–2012
Authors: Wang Mao-Chang
Published: March 2018

Traditional accounting-based performance measurement systems often fail to account for changes in firms’ economic substances. Scholars have argued that market value added and cash value added methods are better value-based performance measurement systems that accurately reflect economic substance. This article examines the relationship among market value added, cash value added, and corporate governance for Taiwanese-listed firms. The results show cash value added to have a positive relationship to the market value added. The corporate governance variables have a positive or negative moderation effect on the relationship between cash value added and market value added systems. The moderation effect of the corporate governance variables on the market value added differs from cash value added.
An Optical Fiber Sensor Method for Simultaneously Monitoring Corrosion and Structural Strain Induced by Loading
Authors: Mao Jianghong , Xu Fangyuan , Jin Weiliang , Gao Qian , Xu Yidong , Xu Chen
Published: March 2018

Monitoring the entire process of concrete corrosion is critical for assessing the remaining life of the structure and determining if maintenance is needed. In this study, the long-distance embedded optical fiber sensor (LEOFS) and the embedded corrosion optical fiber sensor (ECOFS) were both embedded to form a smart reinforced concrete beam that could simultaneously sense loading and corrosion. The structural strain induced by loading was recorded by the LEOFS; meanwhile, the structural strain induced by corrosion was monitored by the ECOFS. The experimental result shows that the aluminum-plastic tube makes the LEOFS effective for long-term monitoring in the corrosive environment. The result also indicates that selecting an appropriate location for the ECOFS leads to high accuracy measurement of strain induced by corrosion. The data of the ECOFS are meaningful for judging the corrosion cracking moment and for estimating the corrosion crack width for the entire corrosion process.
Manihot esculenta Peel Powder: Effective Adsorbent for Removal of Various Textile Dyes from Aqueous Solutions
Authors: Parvathi C. , Shoba U. S. , Prakash C. , Sivamani S.
Published: March 2018

This investigation is aimed to examine the efficiency of dye removal by activated carbon prepared from the peel of Manihot esculenta, which is commonly known as cassava, a waste obtained from sago industries. The effluents containing reactive, direct, acid, alkali, or sulfur dyes were treated with the carbon obtained from cassava peels, which were activated thermally as well as by using acid, alkali, and silver nitrate (AgNO3). The characterization of these carbons was done, and the effect of the parameters pH, concentration, contact time, adsorption dosage, and temperature were studied for each carbon and dye removal. The results of the study indicate that AgNO3-impregnated carbon is more effective in removing the dyes. The equilibrium time is found to be 150 min for reactive, direct, and sulfur dyes and 180 min for acid and basic dyes. The highest percentage dye removal of around 90 % is achieved with AgNO3-impregnated carbon, and the lowest is achieved with alkali-treated carbon. Next to AgNO3-impregnated carbon, acid-treated carbon demonstrates effective dye removal followed by thermally activated carbon and alkali-treated carbon. AgNO3-activated carbon was found to be most effective in removing the basic dye. The order of effectiveness for AgNO3-treated carbon is basic dye > direct dye > sulfur dye > acid dye > reactive dye. The characterization results of AgNO3-activated carbon corroborate its effectiveness in dye removal by indicating greater surface area and higher porosity.
Reexamining Dis/Similarity-Based Tests for Rare-Variant Association with Case-Control Samples
Authors: Wang Charlotte , Tzeng Jung-Ying , Wu Pei-Zhen , Preisig Martin , Hsiao Chuhsing Kate
Published: March 2018

A properly designed distance-based measure can capture informative genetic differences among individuals with different phenotypes and can be used to detect variants responsible for the phenotypes. To detect associated variants, various tests have been designed to contrast genetic dissimilarity or similarity scores of certain subject groups in different ways, among which the most widely used strategy is to quantify the difference between the within-group genetic dissimilarity/similarity (i.e., case-case and control-control similarities) and the between-group dissimilarity/similarity (i.e., case-control similarities). While it has been noted that for common variants, the within-group and the between-group measures should all be included; in this work, we show that for rare variants, comparison based on the two within-group measures can more effectively quantify the genetic difference between cases and controls. The between-group measure tends to overlap with one of the two within-group measures for rare variants, although such overlap is not present for common variants. Consequently, a dissimilarity or similarity test that includes the between-group information tends to attenuate the association signals and leads to power loss. Based on these findings, we propose a dissimilarity test that compares the degree of SNP dissimilarity within cases to that within controls to better characterize the difference between two disease phenotypes. We provide the statistical properties, asymptotic distribution, and computation details for a small sample size of the proposed test. We use simulated and real sequence data to assess the performance of the proposed test, comparing it with other rare-variant methods including those similarity-based tests that use both within-group and between-group information. As similarity-based approaches serve as one of the dominating approaches in rare-variant analysis, our results provide some insight for the effective detection of rare variants.
Self-Identified Tobacco Use and Harm Perceptions Among US Youth
Authors: Agaku Israel , Odani Satomi , Vardavas Constantine , Neff Linda
Published: March 2018

BACKGROUND:

We investigated tobacco-related self-identity and risk perceptions among adolescent tobacco users.

METHODS:

Data were analyzed for 20 675 US sixth- to 12th-graders from the 2016 National Youth Tobacco Survey. Students who reported past-30-day use of a specific tobacco product or ≥2 products but denied having used “any tobacco product” in the past 30 days were classified as not self-identifying as tobacco users. Tobacco product harm perceptions were further assessed across products. Descriptive and multivariable logistic regression analyses were performed.

RESULTS:

Among past-30-day users of ≥1 specific tobacco product type, those denying having used any tobacco products in the past 30 days included single-product users of roll-your-own and/or pipe tobacco (82.2%), electronic cigarettes (e-cigarettes) (59.7%), cigars (56.6%), hookah (44.0%), smokeless tobacco (38.5%), and cigarettes (26.5%) as well as poly-tobacco users (12.7%). The odds of denying using any tobacco products were higher among those without symptoms of nicotine dependence than those with symptoms (adjusted odds ratio = 2.16); and those who access their tobacco products via social sources than those who bought them (adjusted odds ratio = 3.81; all P < .05). Among those believing “all tobacco products” were harmful, single-product users of the following believed their own product was not harmful: e-cigarettes (74.6%), hookah (56.0%), smokeless tobacco (41.8%), and cigarettes (15.5%).

CONCLUSIONS:

Many of those who used certain tobacco products exclusively did not self-identify as tobacco users. Increasing the sensitivity of questions used to assess youth tobacco use in surveys and clinical settings can mitigate nondisclosure or underreporting of true tobacco use status.
Wnt/?-Catenin Signalling during Liver Metabolism, Chronic Liver Disease and Hepatocarcinogenesis
Authors: Shirolkar Gayatri D , Pasic Sara , Gogoi-Tiwari Jully , Bhat Manoj K , Olynyk John K , Dharmarajan Arun , Tirnitz-Parker Janina EE
Published: March 2018

Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely, cirrhosis, liver failure and hepatocellular carcinoma represent major global challenges. The most common initiators of progressive CLD are viral hepatitis and long-term alcohol abuse as well as steatosis and steatohepatitis. Irrespective of the underlying aetiology, a common feature of CLD is the formation of hepatic ductular reactions, involving the proliferation of liver progenitor cells (LPCs) and their signalling to fibrosis-driving hepatic stellate cells. The Wnt/?-catenin pathway has been found to regulate development, stemness and differentiation, and alterations in its activity have been associated with tumour development. Recent data highlight the role of Wnt/?-catenin signalling in hepatic metabolism, steatosis and cancer, and suggest targeting of this pathway as a promising molecular strategy to potentially inhibit CLD progression and hepatocarcinogenesis.
Resistance to Pepper huasteco yellow vein virus and its heritability in wild genotypes of Capsicum annuum
Authors: Retes-Manjarrez Jesús Enrique , Hernández-Verdugo Sergio , Pariaud Benedicte , Hernández-Espinal Luis Alberto , Parra-Terraza Saúl , Trejo-Saavedra Diana Lilia , Rivera-Bustamante Rafael Francisco , Garzón-Tiznado José Antonio
Published: March 2018

Background: Pepper huastecto yellow vein virus (PHYVV) is one of the main viruses affecting pepper (Capsicum spp.) plants in Mexico.Question: Why there are no pepper resistant cultivars to PHYVV currently? Could it be due for the lack of new pepper resistant sources and knowledge about the heritability of the resistant trait?Study species: Capsicum annuum, Pepper huasteco yellow vein virus and Bemisia tabaci.Study site: Culiacan Sinaloa, Mexico; January 2013 to August 2014.Methods: Two assays were performed in 2013 and 2014 with three resistant wild lines of Capsicum annuum in the S2 and S3 generation under greenhouse conditions to analyze the resistance to the Pepper huasteco yellow vein virus (PHYVV) and its heritability. Plants were inoculated with PHYVV through Bemisia tabaci G. and by grafting.Results: Line UAS12 showed a significantly higher proportion of resistant plants, longer incubation time, and less amount of viral DNA, followed by lines UAS13, UAS10 and the Maverick cultivar under both inoculation methods in both assays. Distribution of symptoms revealed a bimodal tendency in both assays. The novel gene "CchGLP" which confer resistance to PHYVV in pepper plants, was identified in the three lines evaluated on this study. Heritability of line UAS12 was of 0.35 and 0.26 in the insects and grafting inoculations, and of 0.58 and 0.10 in the first and second assays, respectively. Lines UAS13 and UAS10 showed close to zero heritability in the first and second assays with both inoculation methods.Conclusions: Line UAS12 is the most promising genetic resource for its high resistance and for showing heritability for the resistance trait. The intermediate resistance of lines UAS13 and UAS10 could be also useful for breeding programs. At least two genes are involved in the resistance trait to PHYVV. Part of the resistance shown in these lines may be due to the presence of the "CchGLP" gene. Line UAS12 count with variability for the resistant trait and can, therefore, be used to improve resistance and the other two lines possibly are stable as they did not show heritability.
Ecology and distribution of macroscopic algae communities in streams from the Basin of Mexico
Authors: Rodríguez-Flores Rogelio , Carmona-Jiménez Javier
Published: March 2018

Background: Several studies of lotic ecosystems have provided important ecological information on the influence of environmental heterogeneity on macroscopic algae composition.Hypothesis: The highest species diversity will occur during the cold-dry season, correlated to low temperature and oligothrophic water, while the distribution of each species will be related to heterogeneity of habitat and its dispersal strategies.Studied species: Twenty-two species of macroscopic algae of different Phyla (Chlorophyta, Cyanobacteria, Heterokontophyta and Rhodophyta).Study site: The macroscopic algae composition was described for 35 permanent mountain streams in the Basin of Mexico from 2012 to 2015.Methods: Algae species, physico-chemical water conditions and microhabitat factors were recorded in situ at each contrasting season. The relationship between diversity and the environmental factors was statistically evaluated by Canonical Correspondence Analysis and a Spearman test. Results: Macroscopic algae recorded had biological features and environmental abilities that separated them into two groups. The first included the most frequent and abundant species: Nostoc parmelioides, Placoma regulare, Prasiola mexicana and Vaucheria bursata . The second included species restricted to certain habitats:  Draparnaldia mutabilis, Tetraspora gelatinosa , Batrachospermum gelatinosum and Paralemanea mexicana . Each Phyla responds differentially to the spatial heterogeneity of the streams, but the species does not change between contrasting seasons.Conclusions: Local and spatial environmental variables explain differences in richness and distribution of species on the studied area; however, species composition does not vary widely among sampling sites. Cyanobacteria and Chlorophyta are more affected by local environmental variables, whereas Rhodophyta is more influenced by spatial variables.
Degree of domestication influences susceptibility of Theobroma cacao to frosty pod rot: a severe disease devastating Mexican cacao
Authors: Albores-Flores Victor J. , García-Guzmán Graciela , Espinosa-García Francisco J. , Salvador-Figueroa Miguel
Published: March 2018

Background: The three -main  cacao ( Theobroma cacao ) varieties cultivated in México are: Criollo, Forastero, and Trinitario. Each variety has a different fruit setting time and has been subjected to several selection stages. The aim of this study was to determine the susceptibility of the three cacao varieties to Frosty pod rot caused by Moniliophthora roreri . We also analyzed the physicochemical properties of the pericarp of the three varieties and its domestication age.Question: Is there a relationship between the degree of domestication of the cacao variety and its susceptibility to Frosty pod rot?Studied species: Theobroma cacao fruits.Study site: A cacao plantation in Chiapas, Mexico.Methods:  The content of moisture, lignin, phenols, peroxidase activity and hardness of the pericarp were analyzed in the middle zone of healthy fruits at 4, 8 and 12 weeks of development. Number of healthy and infected fruits were recorded every week.Results: The highest susceptibility to Frosty pod rot was found in the immature stage of fruits from the Criollo variety. The disease was mostly found in the mid-zone of the fruit. The Criollo variety was the most susceptible. This variety showed the highest moisture values and the lowest values of the other measured parameters.Conclusions: The finest cacao is obtained from the Criollo variety, the one with the highest degree of domestication, and also the most susceptible to frosty pod rot. We suggest using material from wild Criollo populations and from the Forastero and Trinitario varieties in future breeding and selection programs.
Surgical management for mesenteric cysts in pediatric patients: a single center experience
Authors: Gafar Ahmed M. , Batikhe Mohamed Y.
Published: March 2018

Background: Mesenteric cysts are exceptional abdominal lesions of childhood. Presentation may vary with broad spectrum of symptoms from asymptomatic mass and nonspecific complaints to an acute abdomen. Objectives of this study were to present a series of patients with mesenteric cysts and to analyze our experience with emphasis on the presentation, management, and outcome.Methods: This observational study included thirteen children were diagnosed and treated for mesenteric cysts. All cases subjected to clinical evaluation, laboratory investigations and radiological studies. The diagnosis was confirmed on laparotomy. Ethics committee approval was obtained. The main data which extracted and analyzed included demographic data, operative finding, postoperative complications and duration of hospital stay. Data were analyzed using SPSS for Windows software and P value of ≤ 0.05 was considered significant.Results: There were 13 patients with mesenteric cyst, 5 girls and 8 boys. The ages ranged from neonate to 8 years. Abdominal mass and pain was the main presenting symptoms. Prenatal diagnosis established in two cases. Laparotomy performed in all cases. Small bowel mesentery is the commonest site. Two patients required urgent surgery. Surgical procedures included cyst excision with or without intestinal resection. Chylolymphatic cyst was documented in 4 cases. Post-operative complications reported in 2 cases.Conclusions: Mesenteric cysts are unusual in children with variable clinical presentation. Complete excision was feasible in nearly all cases, bringing a favorable outcome. The possibility of this disease entity should be considered as the cause of acute abdomen.
Estratégias de prevenção e pósvenção do suicídio: Estudo com profissionais de um Centro de Atenção Psicossocial
Authors: De Alcântara Müller Sonia , Silveira Pereira Gerson , Basso Zanon Regina
Published: March 2018

O suicídio é considerado um problema de saúde pública que vêm sendo mundialmente debatido.  No Brasil, a região Sul tem se destacado com altos índices de suicídio, alertando profissionais e pesquisadores sobre a temática. O estudo objetivou investigar o desenvolvimento de estratégias de prevenção e pósvenção ao suicídio em um Centro de Atenção Psicossocial (CAPS). Especificamente, buscou-se verificar ações realizadas referentes à assistência aos sujeitos que tenham ideado, tentado ou cometido suicídio, e aos seus familiares, além de investigar sobre as percepções dos profissionais do CAPS sobre o suicídio. Realizou-se um estudo de caso exploratório. Foram entrevistados cinco profissionais do CAPS, e os dados foram analisados com base na Análise de Conteúdo qualitativa. Os profissionais falaram sobre estratégias para manejo do suicídio, citando a importância da atuação em rede e em equipe, do atendimento humanizado e da atenção à família. Também reportaram sentimentos que indicam sofrimento e empatia. Elaborou-se um modelo de planejamento técnico ilustrando estratégias para a prevenção e pósvenção ao suicídio. Por fim, torna-se evidente que as políticas públicas devem dispor de estratégias intervencionais em relação à prevenção e pósvenção ao suicídio, valorizando e qualificando profissionais da saúde.
Evidências de validade para testes de Impulsividade e Atenção no contexto do trânsito
Authors: Jesuíno Ana Deyvis Santos Araújo , Rueda Fabián Javier Marin
Published: March 2018

Atenção e impulsividade podem influenciar na condução de um veículo automotor. Nesse sentido, o objetivo deste estudo foi buscar evidências de validade de critério para testes que avaliam tais construtos. Participaram 201 candidatos à obtenção e renovação da Carteira Nacional de Habilitação (CNH) em seis clínicas de avaliação psicológica pericial no trânsito do Piauí, com idades entre 18 a 68 anos (M=29,64; DP=11,31), sendo 115 (57,2%) do sexo masculino e escolaridade do Ensino Fundamental ao Ensino Superior. Os candidatos à CNH responderam ao TEACO-FF, TEADI e TEALT, uma prova de conhecimentos sobre o trânsito, e a EsAvI. Os candidatos à renovação responderam ao TEACO-FF, TEADI e TEALT, EsAvI e o Questionário de Comportamento do Motorista (QCM). Não foram encontradas diferenças entre candidatos à 1ª CNH e candidatos à Renovação. Evidenciou-se correlações positivas entre os fatores Falta de Concentração e Persistência e Audácia e Temeridade, da EsAvI, com Violações do QCM, enquanto que com o fator Controle Cognitivo a correlação foi negativa. A pontuação total da prova de conhecimentos apresentou correlação positiva e significativa com TEADI. Os resultados indicaram uma capacidade preditiva dos testes de atenção e impulsividade diante dos instrumentos utilizados como critérios, o que lhes confere a evidência
Introjeção de Normas Sociais e Expressão Indireta de Preconceito em Crianças
Authors: Vrijdags Amanda Cezar , Fernandes Sheyla Christine Santos
Published: March 2018

Este trabalho visa contribuir com o estudo da expressão indireta do preconceito contra negros em crianças considerando o papel da introjeção das normas sociais. Objetivou-se analisar a expressão indireta do preconceito em crianças de 5 a 10 anos de idade. Especificamente, avaliou-se expressão indireta do preconceito: 1) em função de três contextos de resposta; 2) em função da cor da pele; 3) comparando crianças de 5 a 7 anos versus 8 a 10 anos. Contou-se com a participação de 40 crianças de uma escola municipal da cidade de Maceió. Para comparar as variáveis envolvidas, foram realizadas técnicas de estatística descritiva e o teste de associação X2 (qui-quadrado). Os resultados indicaram que existe uma relação entre contexto e expressão do preconceito, que pode estar relacionada com as hipóteses da expressão indireta de preconceito racial. A faixa etária não pareceu exercer uma diferença significativa na expressão do preconceito. Concluiu-se que as crianças expressam preconceito de uma forma sutil e indireta, uma vez que o fazem somente quando existe uma justificativa para isso que não seja a cor da pele do alvo.
Consequências psicossociais atreladas ao consumo precoce de bebida alcoólica
Authors: Rodrigues Giovana , Krindges Cris Aline
Published: March 2018

O presente estudo teve como objetivo investigar as consequências psicossociais atreladas ao inicio precoce de consumo de álcool na adolescência em adultos que fizeram uso abusivo de bebida alcoólica. Participaram deste estudo dois homens maiores de 18 anos de idade, vinculados ao grupo de etilistas do Centro de Atenção Psicossocial (CAPS) de um município do Rio Grande do Sul. A pesquisa teve como base a abordagem qualitativa e foi de cunho exploratório a partir de estudos de casos coletivos. Para obtenção dos dados utilizou-se questionário sociodemográfico e entrevista semiestruturada. Com este estudo compreendeu-se que a família se mostrou como principal influenciadora do consumo precoce, e esse início pode ter influenciado os participantes a consumirem abusivamente o álcool na idade adulta. Além disso, causou prejuízos ao longo de seu desenvolvimento, como laços afetivos prejudicados com seus familiares e dificuldades laborais. Por fim, o CAPS mostrou-se como importante aliado no tratamento dessas pessoas, ao auxiliar no reestabelecimento de vínculos com seus familiares e proporcionar um ambiente livre de julgamentos.Palavras-chaves: Abuso de álcool, adolescência, serviços de saúde mental, homens adultos
Bem-Estar Espiritual e Religião em Doutorandos de Universidade Comunitária
Authors: Thurow Ane Cristina , Charão Caroline De Souza , Mortagua Eloiza De Oliveira , Souza Luciano Dias de Mattos
Published: March 2018

O bem-estar espiritual conecta-se ao significado da vida de maneira ampla, possibilitando o equilíbrio emocional, a qualidade de vida e o desenvolvimento de valores éticos e morais que podem interferir nas questões biológicas, psicológicas e sociais do indivíduo. Este estudo objetivou avaliar o bem-estar espiritual em doutorandos de uma universidade comunitária de Pelotas-RS a fim de verificar sua associação com fatores sociodemográficos e autoavaliação de saúde e vida. Trata-se de um estudo transversal, com amostra de conveniência, que examinará o bem-estar espiritual em doutorandos de Programas de Pós-Graduação. Os participantes responderam ao questionário com fatores sociodemográficos, autoavaliação da saúde e da vida e ao instrumento – versão longa da Escala de Bem-Estar Espiritual (EBE) – que são autoaplicáveis. Foram utilizados os testes t, ANOVA e correlação de Pearson para a análise. Os resultados apresentaram maiores escores de bem-estar espiritual e religioso em doutorandos que têm alguma religião, realizam práticas religiosas e tem frequência na atividade; observou-se correlação significativa do bem-estar religioso com a renda familiar. O estudo mostra a importância do bem-estar espiritual como fator de proteção em questões sociais, psicológicas e profissionais, principalmente em momentos tensos e de sobrecarga em que vivem os doutorandos.Palavras-chave: Espiritualidade, Religião, Educação Superior
Mutations in COL1A1 and COL1A2 Genes Associated with Osteogenesis Imperfecta (OI) Types I or III.
Authors: Augusciak-Duma Aleksandra , Witecka Joanna , Sieroń Aleksander L. , Janeczko Magdalena , Pietrzyk Jacek J , Ochman Karolina , Galicka Anna , Borszewska-Kornacka Maria K , Pilch Jacek , Jakubowska-Pietkiewicz Elzbieta
Published: March 2018

Over 85% of osteogenesis imperfecta (OI) cases associates to mutations in procollagen type I genes (COL1A1 or COL1A2), however, no hot spots were linked to particular clinical phenotypes. The 8 patients whom were clinically diagnosed with OI are from Polish population with no ethnic background indicated. Six unpublished mutations were detected in eight patients diagnosed with OI. Genotypes for polymorphisms (Sp1 - rs1800012 and PvuII - rs412777), linked to bone formation and metabolism were also determined. In COL1A1 gene the mutations were found in exons 2, 22, 50 and in introns 13 and 51. In COL1A2 one mutation was identified in exon 22. Mutations of deletion type in COL1A1 that resulted in OI type I an effect neither on collagen type I secretion nor its intracellular accumulation were detected. Also, a single base substitution in I13 (c.904-9 G>T) was associated with OI type I. The OI type III was associated with single base change in I51 of COL1A1, possibly causing an exon skipping. Also, a missense mutation in COL1A2 changing Gly®Cys in the central part of triple helical domain of the collagen type I molecule caused OI type III. It affected secretion of heterotrimeric form of procollagen type I. However, no intracellular accumulation of procollagen chains could be detected. Mutation in COL1A2 affected its incorporation to procollagen type I. The results shall help in genetic counseling of OI patients and provide rational support in making by them and their families conscious, life important decisions.
Las ideas de los docentes de ciencias con respecto al aprendizaje de sus alumnos
Authors: Hermano Rosario , Vique María Inés
Published: March 2018

El presente trabajo de investigación es una aproximación a las concepciones de aprendizaje que tienen los docentes de Biología, Física y Química de Ciclo Básico en relación al aprendizaje de sus alumnos. Dado que no existe una única visión del mundo, ni de la naturaleza del hombre, ni de la educación, no existe una única concepción de aprendizaje, y la concepción de aprendizaje de cada profesor condicionará su práctica docente de tal forma que implícita o explícitamente aparecerá reflejada en su accionar diario en el aula.
El uso de los medios tecnológicos y sus posibles implicancias en el quehacer didáctico
Authors: González Daniela , González Virginia
Published: March 2018

La progresiva aceleración de los avances tecnológicos ha generado una dinámica de cambio constante en lo que a la comunicación se refiere. La información que se genera en cualquier parte del mundo se puede obtener en pocos minutos y está al alcance de la sociedad en su totalidad y en especial de los jóvenes. ¿Está la educación de hoy acompasando esta dinámica de cambio? ¿Están los educadores acompasando el cambio, en el sentido de apoyar en forma instrumental los procesos de formación? ¿Están los educadores brindando las herramientas necesarias para que los educandos construyan sus conocimientos en forma activa?
La reconstrucción del discurso didáctico
Authors: Lorenzo Enrique
Published: March 2018

La pluralidad de marcos y referentes teóricos viene siendo un rasgo inherente de cualquier disciplina. Un rastreo crítico de las principales corrientes nos permitirá conocer cuáles han sido los aspectos nucleares en su construcción y evolución. En este artículo analizaremos las más destacadas corrientes didácticas, con la intención de descubrir su campo de acción y los cambios operados en el mismo.
THE DIFFERENCE OF MAP1LC3 LEVEL AS MACROPHAGE AUTOPHAGY MARKER BETWEEN RESISTANT AND SENSITIVE TUBERCULOSIS PATIENTS ON RIFAMPICIN
Authors: Wulandari Dian Novita , Nugraha Jusak , Soedarsono Soedarsono
Published: March 2018

M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be phagocytosed by the alveolar macrophage cells and can survive in the phagosome. The macrophage plays a role in innate immunity towards an infection using autophagy by removing the microbe directly via phagocytosis. When bacteria phagocytosized, vacuole membrane formed double membranes called autophagosome, and followed by degradation by lysosome, which known as  autolysosome. Induction of autophagy can be observed on the formation of microtubule-associated proteins 1B lightchain 3B (MAP1LC3B/LC3). MAP1LC3B is protein that have role at autophagic way for selection autophagy substrate and biogenesis. In this study we are used serum from patients TB with rifampicin resistant and rifampicin sensitive as control. Samples were divided using gene expert to differentiate between resistant and sensitive rifampicin.This research aims to compare MAP1LC3B levels in resistant and sensitive rifampicin to study macrophages respond in autophagic way in tuberculosis patients, and give information for define therapy plan to improve therapy for MDR-TB patients. Type of this research is a case control study design with cross sectional research with each groups sample is 19 from age 18-65 years old. Result, MAP1LC3B serum levels on the rifampicin resistant group are lower compared to rifampicin sensitive group. This occur because MTB is able to hide and evade innate immune defense mechanisms. MTB can maintain intracellular growth inside the phagosome by inhibiting phagolysosome formation in autophagy process especially inhibit MAP1LC3B formation by PDIM.
Organic Production as a Key for Sustainable Development in Wine Industry in the Czech Republic
Authors: Formánková Sylvie , Chládková Helena , Beránková Anita
Published: March 2018

The paper describes the environment sector of organic winery in the Czech Republic and finds opportunities for Czech winegrowers to sustain the industry and contribute to its future development. Organic viticulture has changed dramatically. Organically farmed vineyards formed 4.9% share of the total area of vineyards in the Czech Republic in 2011and 6.1% in 2012. Czech organic wines have much to offer to consumers. They have received many prestigious awards at international competitions; however the foreknowledge of customers about such wines is very low as these are drunk mostly by regular consumers. That is why a change should be made. The popularity of organic wine is expected to grow mainly in the foreign markets. Although the Czech organic wines have already found their consumers, the need for additional marketing activities that will result in expansion of its portfolio of consumers, are required.

JEL codes: M1, M11, M 13, M14
Az organikuscímke-hatás a marketing irodalomban: imázstranszfer, halo-hatás és jelzés
Authors: Kiss Marietta , Kontor Enikő , Kun András István
Published: March 2018

Áttekintve az organikuscímke-hatás releváns marketing irodalmát megállapíthatjuk, hogy az imázstranszfer és a halo-hatás teszi ki az organikuscímke-hatást magyarázó publikációk döntő többségét, míg a jelzési irodalom mennyiségét tekintve (egyelőre) marginális. Ennek egyik oka lehet a szerzők szerint, hogy a jelzési modellek alkalmazása egyszerre igényli a marketing ismereteket és a közgazdaságtan módszereiben való jártasságot, ami mind a lehetséges szerzők számát korlátozhatja, mind a befogadó folyóiratokét. Ugyanakkor megállapíthatjuk, hogy a jelzési irodalom területén is születtek jelentős eredmények, tehát érdemes lenne ezt a kutatási vonalat a jövőben erősíteni.Feltűnő továbbá, hogy a feldolgozott tanulmányok egy részében az imázstranszfer és a halo-hatás koncepciói keverednek, több esetben szinonimaként használják azokat, holott jól elkülöníthetők egymástól, definícióik a szakirodalomban ismertek. Ez megnehezítheti a témában született eredmények értékelését és összevetését.Megállapítható továbbá, hogy maga az organikuscímke-hatás jelensége számos alkalommal, számos termékfajta és terméktulajdonság esetében megerősítést nyert; létezéséhez mára kétség nem fér. Ami továbbra sem tisztázott kellő mértékben, és amire cikkünkben mi is felhívtuk a figyelmet, az a jelenség vizsgálatának és magyarázatának elméleti kerete. A bemutatott három magyarázóelv (transzferhatás, halo-hatás, jelzés) külön-külön és egymás mellett is megállhatja a helyét, azonban a szerzők hiányolják a lehetséges magyarázatok alkalmazhatóságának vizsgálatát a szakirodalomból. Mint minden társadalmi-gazdasági jelenség esetében, nyilván az organikus címkék hatásainak esetében is igaz, hogy többféle modellel leírhatóak, elemezhetőek, de a konkrét szituációk paramétereitől függően ezek közül egyiknek vagy másiknak nagyobb a magyarázó ereje. Hasznos jövőbeli kutatási irány lehetne tehát az egyes modellek különböző feltételek közötti alkalmazhatóságának vizsgálata, esetleg kombinált modellek kidolgozása, melyek a komplex, valós szituációkat sikeresebben közelíthetnék meg.

JEL-kódok: D82, Q13, L15
Development of Piezoelectric Harvesters with Integrated Trimming Devices
Authors: Doria Alberto , Medè Cristian , Fanti Giulio , Desideri Daniele , Maschio Alvise , Moro Federico
Published: March 2018

Piezoelectric cantilever harvesters have a large power output at their natural frequency, but in some applications the frequency of ambient vibrations is different from the harvester’s frequency and/or ambient vibrations are periodic with some harmonic components. To cope with these operating conditions harvesters with integrated trimming devices (ITDs) are proposed. Some prototypes are developed with the aid of an analytical model and tested with an impulsive method. Results show that a small trimming device can lower the main resonance frequency of a piezoelectric harvester of the same extent as a larger tip mass and moreover generates at high frequency a second resonance peak. A multi-physics numerical FE model is developed for predicting the generated power and for performing stress-strain analysis of harvesters with ITDs. The numerical model is validated on the basis of experimental results. Several configurations of ITDs are conceived and studied. Numerical results show that harvesters with ITDs are able to generate relevant power at two frequencies owing to the particular shape of the modes of vibration. The stress in the harvesters with ITDs is smaller than the stress in the harvester with a tip mass trimmed to the same frequency.
A Closed-Form Error Model of Straight Lines for Improved Data Association and Sensor Fusing
Authors: Sommer Volker
Published: March 2018

Linear regression is a basic tool in mobile robotics, since it enables accurate estimation of straight lines from range-bearing scans or in digital images, which is a prerequisite for reliable data association and sensor fusing in the context of feature-based SLAM. This paper discusses, extends and compares existing algorithms for line fitting applicable also in case of strong covariances between the coordinates at each single data point, which must not be neglected if range-bearing sensors are used. Besides, particularly the determination of the covariance matrix is considered, which is required for stochastic modeling. The main contribution is a new error model of straight lines in closed form for calculating fast and reliably the covariance matrix dependent on just a few comprehensible and easily obtainable parameters. The model can be applied widely in any case when a line is fitted from a number of distinct points also without a-priori knowledge of the specific measurement noise. By means of extensive simulations the performance and robustness of the new model in comparison to existing approaches is shown.
Evapotranspiration Rates of Turf Bermudagrasses under Nonlimiting Soil Moisture Conditions in Oklahoma
Authors: Amgain Naba R. , Harris Dustin K. , Thapa Santanu B. , Martin Dennis L. , Wu Yanqi , Moss Justin Q.
Published: March 2018

Due to limited water availability and increasing water costs, it is essential to identify and utilize turfgrasses with reduced water use rates. The objective of this study was to evaluate the evapotranspiration rates of bermudagrass (Cynodon spp.) genotypes under nonlimiting soil moisture conditions in the field at Stillwater, OK. Evapotranspiration rates of 10 bermudagrass genotypes were determined using mini‐lysimeters with calcined clay as rooting media. Daily evapotranspiration (ET) rates were measured before dawn by weighing the mini‐lysimeters from August to September in 2013, 2014, and 2015. A significant genotype × year effect was found. Therefore, data were analyzed separately for each year. Within years, the genotype × date effect was significant only in 2014. In 2013, ‘TGS_U3’, ‘TifTuf’, and ‘Premier’ used more water than OKC 1302, OKC 1163, ‘Latitude 36’, ‘Tifway’, and OKC 1131. In 2014, TifTuf, ‘Celebration’, Tifway, and OKC 1302 used more water than Premier, TGS_U3, ‘NorthBridge’, OKC 1163, and OKC 1131. In 2015, TifTuf, Celebration, and Latitude 36 used more water than Premier, OKC 1302, OKC 1163, OKC 1131, and NorthBridge. TifTuf ranked consistently in the group of genotypes with the highest ET rates, whereas OKC 1131 ranked consistently in the group of genotypes with lowest ET rates in 2013, 2014, and 2015. The differences in ET rates show the potential for breeding programs to develop bermudagrass cultivars with lower ET rates, which may result in reduced overall ET requirements.
Dietary Reference Intake and Nutritional Yield of Lentils in the Northern Great Plains
Authors: Graham Christopher , Beck R. , Thavarajah D.
Published: March 2018

Micronutrient deficiencies remain unacceptably high in the diets of many impoverished communities in both developed and developing countries. However, despite declining consumption patterns, pulse crops such as lentils (Lens culinaris Medik.) can serve as important crops to fill the micronutrient gap. In the present study, three lentil cultivars grown over a 2‐yr study period at two locations (Bison and Wall, SD) in the Northern Great Plains were evaluated to assess the crop's ability to meet the daily nutritional requirements of critical micronutrients: Fe, Mg, K, Se, and Zn. Results were found to vary significantly by location and by cultivar. The greatest differences were found for Se. Between cultivars, concentrations ranged from 115 to 210% of daily requirements per 100 g lentils at Bison and 295 to 381% at Wall. On the basis of average yields per hectare and nutrient concentrations, lentils were found on average to meet the yearly recommended intake requirements of 13 and 20 adult females for Fe, 9 and 13 adults for Mg, 7 and 11 adults for K, 49 and 125 adults for Se, and 14 and 26 adults for Zn between the two study sites, respectively.
Estimation of annual reference condition of Chlorophyll-a based on the segmental linear regression and power-law relationship in Taihu Lake
Authors: Wang Liang , Hua Zulin , Wang Yulin
Published: March 2018

The reference conditions of Chlorophyll-a in lakes should be established in order to improve the water quality in these water bodies. A new method using segmental linear regression was developed to estimate the reference condition of Chlorophyll-a. The method can overcome the shortcomings of other methods, such as the quantile-selection-based method, which contains a certain level of subjectivity. The new method was used to estimate the annual reference condition of Chlorophyll-a in Taihu Lake. The log–log segmental regression results indicate that the distribution of specific volume (reciprocal of concentration) of Chlorophyll-a in Taihu Lake had a power-law tail. Both segmental regression and bootstrap approaches show two credible change points in the power-law relationship. This study's analysis shows that the value of 4.4 mg·m−3 was an appropriate annual reference value of Chlorophyll-a in Taihu Lake. Thus, the method would be useful in determining the numerical reference conditions of Chlorophyll-a for other shallow lakes.
Removal of atenolol from aqueous solutions by multiwalled carbon nanotubes modified with ozone: kinetic and equilibrium study
Authors: Dehdashti Bahare , Amin Mohammad Mehdi , Pourzamani Hamidreza , Rafati Lida , Mokhtari Mehdi
Published: March 2018

The aim of study is removal of atenolol from aqueous solutions by multiwalled carbon nanotubes modified with ozone. The design of the experiment was adopted across four levels with the L16 matrix arrangement. The factors influencing atenolol adsorption include changes in the pH value, contact time, the dose of the modified multiwall carbon nanotube, and the initial concentration of atenolol in the solution; these factors were evaluated along with the extent of their influence on removal efficiency. Data analyses were performed by the Design Expert 6 software. The results indicated that the pH, contact time, adsorbent dose, and the initial concentration were 7, 20 min, 0.15 g/L and 1 mg/L, respectively. In this state, the removal efficiency was calculated to be 75.79%. The maximum adsorption capacity was obtained as 5.05 mg/g under optimal conditions. The data were analyzed using adsorption models obtained from the isotherm fitting tool software. The results suggested that the data had a greater congruence with the Freundlich model (corrected Akaike information criterion = 2.58). Furthermore, the kinetics of the reactions followed pseudo second order kinetics (R2 = 0.95). Based on this study, it can be concluded that modified multiwall carbon nanotubes enjoy high potential and efficiency as adsorbents for the removal of atenolol from aqueous solutions.
Recent Developments in Controlled Release of Antibiotics
Authors: Ning Ling Gui , Kang En-Tang , Wang Yun Bing , Hu Xue Feng , Xu Li Qun
Published: March 2018

Traditional use of antibiotics through injection or oral ingestion has many disadvantages, such as detrimental
side effects in the host, less effectiveness, high and repeated doses, and development of drug resistance.
For prevention and treatment of implant-associated infections, the continuous local delivery of antibiotics is required.
Thus, there is a strong demand for the development of drug carrier systems to control the release of antibiotics
in a moderate manner over an appropriate timescale. This review summarizes the carrier platforms used
for the loading of antibiotics, and highlights their drug release behaviors as well as in vitro and in vivo antibacterial
properties.
Cognitive Training in Patients with Alzheimer's Disease: Findings of a 12-month Randomized Controlled Trial
Authors: Trebbastoni Alessandro , Imbriano Letizia , Podda Livia , Rendace Lidia , Sacchett Maria Luisa , Campanelli Alessandra , D’Antonio Fabrizia , de Lena Carlo
Published: March 2018

Background:

Cognitive training (CT) is a non-pharmacological intervention based on a set of
tasks that reflect specific cognitive functions. CT is aimed at improving cognition in patients with cognitive
impairment, though no definitive conclusions have yet been drawn on its efficacy in Alzheimer's disease
(AD).

Objective:

To assess the effectiveness of a CT program designed to improve cognition in AD patients.

Method:

This is a randomized, controlled, single-blind, longitudinal trial with a no-treatment control condition
in mild-to-moderate AD. Treated patients received in-group CT twice a week for six months,
whereas controls did not. CT consisted of tasks ranging from paper-and-pencil to verbal-learning exercises.
Participants' cognitive levels were assessed at baseline, post-intervention and 6 months later by
means of a complete neuropsychological test battery. Repeated measures ANOVA was used to analyze
the effect of time on the outcome measures, as well as to compare treated and untreated patients over time,
with demographic data considered as covariates.

Results:

Of the 140 patients enrolled, 45 in the treated group and 85 controls concluded the study. The CT
significantly improved treated subjects' cognitive functions immediately after the CT. Six months later,
some test scores remained stable when compared with those obtained at baseline. The control group performed
significantly worse than the treated group at each time-point, displaying a progressive cognitive
decline over time.

Conclusion:

Our results suggest that CT may improve cognitive functions in patients with AD and may
help to temporarily slow their cognitive decline.
Appropriate Architecture and Urban Design Research Centre for Creative Thinking and Communication
Authors: Bisadi Mona , Mozaffar Farhang , Hosseini Seyed Bagher
Published: March 2018

Progressive research activities, which assess entail factors in future societies, that are strongly dependent on creativity and innovation. This paper considers the built environment as one of the influential aspects of creativity and innovation and seeks its appropriate features. Among various choices, we adopt academic research centers of architecture and urban design for the sake of this study. At first, we identify four effective spatial characteristics, including privacy, beauty, spatial diversity, and proximity. Then, we conduct the analysis based on the survey method and, ultimately, we propose some design patterns in order to enhance the researchers' creativity and innovation.