bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights on the effectiveness of a hybrid learning modality in a BS Pharmacy Program of a local university in the National Capital Region, Philippines: A follow-up study
Authors:   Institute of Pharmacy, University of Makati, JP Rizal Extension, West Rembo, 1215 Taguig City, Philippines, M. Cariaga Maria Fay Nenette
Published: February 2025

The COVID-19 situation in 2020 pushed educational institutions in the Philippines to adopt an online learning modality. Subsequently, through a phased approach, catch-up plan was implemented towards the end of the 2nd semester of the academic year (AY) 2021–2022 and limited onsite laboratory classes were likewise employed during the 1st semester of AY 2022–2023. By the 2nd semester of AY 2022–2023, hybrid learning, which consisted of 50% online and 50% onsite learning delivery mode was implemented as per the Commission of Higher Education (CHED) memorandum order 16, series of 2022. As educational institution transitioned to hybrid learning, questions on the pedagogical effectiveness were raised. This study which consisted of a mixed-method approach was performed to assess if the program learning outcomes (PLOs) of a Bachelor of Science in Pharmacy (BS Pharmacy) program in a local university in the National Capital Region, Philippines were achieved given the transition to hybrid learning modality. Quantitative data were gathered through online survey, while qualitative data were collected via the conduct of open forum and narrative essay. The quantitative findings of the study revealed significant improvements in PLO achievement under the hybrid learning from purely online learning. Qualitative findings highlighted enhanced learning experience, collaborative opportunities and practical skills development aided by the increased onsite engagements. In conclusion, the hybrid learning effectively attained the PLOs, emphasizing the importance of having an onsite learning set-up. The insights from this study contributes to the advancement of pedagogical strategies in the field of pharmacy education as the world may face future challenges such as pandemics.
Effects of various polymers on dissolution improvement of fabricated amorphous clonazepam solid dispersion-an in vitro study
Authors:   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh, Jahan Khurshid , Akter Mousumi ,   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh, Bhowmick Tonmoy ,   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh, Or Rashid Md. Harun ,   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh, Tasnim Sadia ,   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh, Rahman Rimi Rubaya ,   Department of Pharmacy, World University of Bangladesh Sector: 17/H, Uttara, 1230 Dhaka, Bangladesh
Published: February 2025

The 1,4-benzodiazepine derivative clonazepam (Biopharmaceutics Classification System [BCS] class ii) drug, which is a hypnotic and tranquiliser, is almost completely insoluble in water and lipophilic in nature. Since traditional dosage forms typically have a number of drawbacks, solid dispersion (SD) technology can be helpful in improving the way that pharmaceuticals dissolve, absorb and work therapeutically in dosage forms. Our study's objective is to create an SD formulation of the poorly water soluble medication clonazepam (CLZ) with the hydrophilic polymers PEG 4000 and PEG 6000. The main advantages of using water-soluble polymers as carriers are their low toxicity and wide applicability for the majority of medications. Using physical mixing and SD techniques, the polymers were employed with the medication CLZ in varying ratios (1:2, 1:4, 1:6). The production yield, drug content analysis and cumulative drug release of the produced formulations were evaluated. At 60 minutes, only the pure drug exhibited 51% of release. However, the solubility of the medication is significantly increased when hydrophilic polymer is added. With a better drug release by the polymer PEG 6000 and an 80.19% in vitro drug release, the formulation KSD9 showed promise. Furthermore, the other polymer exhibited 59.11% in kneading method and 57.08% in fusion method respectively. Hence the greater carrier content and the prevention of crystallinity in the dispersion, the binary SD produced using various techniques significantly increases the drug's solubility.
Kinetics of quantum reaction-diffusion systems
Authors: Gerbino Federico , Lesanovsky Igor , Perfetto Gabriele
Published: February 2025

We discuss many-body fermionic and bosonic systems subject to dissipative particle losses in arbitrary spatial dimensions dd, within the Keldysh path-integral formulation of the quantum master equation. This open quantum dynamics represents a generalisation of classical reaction-diffusion dynamics to the quantum realm. We first show how initial conditions can be introduced in the Keldysh path integral via boundary terms. We then study binary annihilation reactions A+A\to \emptysetA+A→∅, for which we derive a Boltzmann-like kinetic equation. The ensuing algebraic decay in time for the particle density depends on the particle statistics. In order to model possible experimental implementations with cold atoms, for fermions in d=1d=1 we further discuss inhomogeneous cases involving the presence of a trapping potential. In this context, we quantify the irreversibility of the dynamics studying the time evolution of the system entropy for different quenches of the trapping potential. We find that the system entropy features algebraic decay for confining quenches, while it saturates in deconfined scenarios.
AN IDEAL WAY TO OUR EDUCATIONAL SYSTEM
Authors: M. Vanita , J.P. Pramod , Priya N. B. Yagna
Published: February 2025

Education is the most crucial component for both individual and national development. The current state of education requires significant reforms, including the addition of courses and skills centred on entrepreneurship and agriculture, which will assist the country in producing a large number of scholars and inventors. The pupil should be exposed to nature at every level. We always begin our education. The teaching technique of the school must be altered first, along with the personnel, study guides, facilities, and attitudes of both teachers and pupils. Higher secondary education is the next important stage, and it requires numerous adjustments, chief among them being facilities, classrooms, labs, and a teaching methodology and system they adhere to. All student needs at graduation are the ideal direction for their career and aspirations. The educational system must be modified to reflect students abilities. Every pupil should have a different one. Every student should have confidence in their ability to acquire skills rather than certificates thanks to this educational system. This approach emphasises students mental processes and thinking when they continue their education. This paper presents the process of teaching and learning at every step of an ideal educational system.
SMART BETA PORTFOLIO STRATEGY ON TECHNOLOGY AND FOOD STOCK IN SOUTH KOREA
Authors:   School of Economics and Business, Telkom University, Bandung, Indonesia., Violisa Halim Shaeva , Fitrizal Salim Dwi ,   School of Economics and Business, Telkom University, Bandung, Indonesia.
Published: February 2025

This study discusses the performance of stocks of technology companies and food companies in South Korea in the period January 2019-November 2024 which are attractive to foreign investors due to their strategic position in the global economy. However, companies do not always show good performance. Therefore, a careful investment strategy is needed, including the preparation and management of portfolios. In compiling the portfolio, this study uses a smart beta strategy that has been proven to provide superior returns compared to traditional portfolios. Portfolio management involves two strategies, namely a passive approach and an active approach. This quantitative descriptive study uses open prices from stock data prices that form a portfolio based on selected betas. Weighting is adjusted for higher beta stocks in receiving a larger allocation in the portfolio. This study compares three beta groups (high, medium, and low) and two investment strategies (active and passive) using the Sharpe index.The results of this study indicate that the medium beta group and passive strategy have better performance with competitive return values â€‹â€‹without having to face too much risk. The passive strategy provides a balance between risk return and maintaining stability without dependence on market movements that tend to be volatile.
Perceptual service robot attributes affecting customer value co-creation intention in luxury hotels industry
Authors: Li Qian , Jiang Songyu
Published: February 2025

Service robots have become a trend in hotel services, presenting new opportunities and challenges for the development of the hospitality industry. This study aims to explore how the perceptual attributes of service robots affect customer value co-creation intention in the luxury hotel industry. In China, Shanghai is the city with the most hotels from luxury brands and the city with the highest number of service robots deployed in luxury hotels. Currently, only 11 luxury hotels in Shanghai use service robots. Therefore, this study conducted an online survey of customers who have used service robots in these 11 luxury hotels in Shanghai. A total of 644 responses were collected from customers in luxury hotels in China who have used service robots through convenience sampling. Subsequently, the data underwent a validity analysis, and structural equation modeling was used to process the data. The results indicate that when service robots are perceived as possessing anthropomorphism, animacy, perceived intelligence, and perceived safety, they significantly enhance the customer hospitality experience. These attributes boost the enjoyment and trust customers feel when interacting with the robots, leading to greater engagement during the experience. Notably, likeability lacks significant impact on customer hospitality experience, suggesting that in luxury hotel settings, customers place more emphasis on whether robots possess practical attributes like intelligence and safety. Moreover, the customer hospitality experience serves as a significant mediator, implying the anthropomorphism, as the most critical attribute.
The impact of the forced displacement of universities due to the occupation of certain territories of Ukraine on the effectiveness of their activities: “Top 200 Ukraine” universities ranking
Authors: Sych Tetiana , Panchenko Liubov , Saienko Olga , Ptakhina Olga , Ivanov Yevhen
Published: February 2025

The study targets temporarily displaced universities that changed their location due to the outbreak of the armed military conflict in Ukraine in 2014 and Russia’s full-scale military aggression in 2022. This paper focuses on the leadership of universities in implementing their third mission, which is critical to fostering the economic and social development of the regions. The purpose is to assess the impact of forced, urgent, and unplanned relocation of universities (due to the potential or actual occupation of certain territories of the country by enemy forces) on their effectiveness.According to the rating of Ukrainian universities, “Top 200 Ukraine”, the rating indicators for the last 10 years of temporarily displaced universities from the occupied territories were analyzed. А comprehensive analysis of the challenges faced by temporarily displaced universities in Ukraine was done. Statistical analysis has confirmed the decline in ranking positions by displaced higher education institutions. The findings indicate a minimum five-year decrease in performance metrics for all institutions following relocation, with the success of adaptation to new conditions being contingent upon the institution’s capacity and resources. The data suggest that displaced universities face existential threats and require enhanced support from both governmental and international communities. A review of scholarly research on the strategic management of higher education institutions and their leading role in regional development underscores the necessity of preserving these institutions to facilitate the socio-economic reconstruction of war-affected territories.
Comparative Analysis of Financial Performance in Indonesian Islamic Banks: The Impact of Spin-Offs, Mergers, and Conversion
Authors: Rusmita Sylva Alif , Salleh Marhanum Che Mohd , Samad Khairunnisa Abd
Published: February 2025

This study conducts a comparative analysis of Indonesian Islamic banks' performance before and after spin-off, merger, and conversion. Using a quantitative approach, the research applies paired t-tests and Wilcoxon tests to assess financial performance across six categories: liquidity, financing, efficiency, profitability, capital adequacy, and non-performing financing. Data from six Islamic banks over ten years were analyzed, comparing performance pre- and post-establishment. The findings reveal no significant differences in performance for banks that underwent pure spin-offs. However, banks formed through mergers demonstrated improvements in operational efficiency, return on assets (ROA), and capital adequacy (CAR), while conversions exhibited strong financing performance but faced capital risk and lower profitability. These results suggest that mergers offer a more efficient establishment method for enhancing bank performance, while conversions require careful capital management. The research highlights the importance of strategic decisions regarding the choice of establishment method for Islamic banks, with significant implications for bankers and policymakers aiming to optimize Islamic bank performance.
Efficient or Opportunistic: An Empirical Test of Managerial Discretion of Islamic Banking in Reporting The Earnings
Authors: Abbas Ahmad , Triani Neks , Rayyani Wa Ode , Radwan Maha
Published: February 2025

Managers are responsible for the decision-making related to financial information. They make financial reporting incentives to manage financial data, including the earnings. Banks under Islamic principles seem to affect the probability of problematic managerial behavior in determining earnings. This study determines whether Islamic banking managers' discretion in reporting earnings is efficient or opportunistic. The sample of this study was Islamic commercial banks in Indonesia. The data was obtained from Bank Indonesia and Financial Services Authority. Their financial statements from 2010 to 2016 were analyzed using Moderated Regression Analysis. As reported by the analysis results, managers in Islamic banking are efficient in their discretion while reporting their earnings. Managers tend to level down their earnings when the profitability is exceptionally high at the current earning and movie it to the future earning making the profitability of Islamic banks seem stable.
A természeti erőforrások egyenlőtlen regionális eloszlása : Fókuszban az EU villamosenergia-termelési lehetőségei és korlátai
Authors: Herczeg Balázs , Pintér Éva
Published: February 2025

A természeti erőforrások regionális eloszlása és hozzáférhetősége jelentős hatással van egy adott ország geopolitikai helyzetére, kiváltképp az energiaforrások tekintetében, hiszen az ezekhez való hozzáférés stratégiai fontosságú és befolyásolja az országok energiabiztonságát. Ennek megfelelően az erőforrások biztosítása és fenntartható kezelése fontos kihívások elé állítja a nemzetközi közösséget. Mindeközben az új technológiák és a megújuló ener-giaforrásokon alapuló megoldások fejlődése újraértelmezi a klasszikus geopoli-tikai paradigmákat, mivel ezek kevésbé függenek a földrajzi korlátoktól és hozzájárulnak a környezetvédelemhez. Tanulmányunk célja az EU villamos-energia-termelési adottságainak, lehetőségeinek és korlátainak áttekintése természeti erőforrások tekintetében. Elemzésünk során megvizsgáltuk valam-ennyi fosszilis és nukleáris tüzelőanyagforrás földrajzi eloszlását, az EU meg-újuló energiaforrásainak potenciálját, valamint összehasonlítottuk az egyes energiatermelő technológiák kapacitásfaktorait és elektromos áramtermelő hatékonyságait. Arra a következtetésre jutottunk, hogy az EU jelentős fosszi-lis és nukleáris tüzelőanyag-tartalékokkal nem rendelkezik, így ezek importjá-ra szorul. Ugyanakkor megújuló energiaforrások kiaknázása terén az EU kü-lönböző régiói eltérő potenciállal bírnak, így ezek fejlesztése integrált megkö-zelítést igényel az energiaellátás biztonságának és gazdaságosságának növelése érdekében. A vízenergia kiemelkedik magas energiaátalakítási hatásfoka miatt, míg az atomenergia nagy energiaintenzitással és kapacitásfaktorral rendelke-zik, ami a legoptimálisabb villamosenergetikai technológiákká teszik őket. Emellett a rugalmasan kezelhető földgáztüzelésű erőművekre is jelenleg még szükség van, ezek mintegy áthidaló erőforrásként szolgálnak a megújuló ener-giákra történő átállás tekintetében.
Egészségügyi szektor átfogó ismertetése a szervezeti struktúrától az életpályamodellig
Authors: Kelen Andrea
Published: February 2025

Garaj Erika (szerk., 2020): Egészségügyi szervezetek menedzsmentje főiskolai jegyzet hallgatóknak, Akadémia Kiadó, Budapest, 150 p. ISBN 978-963-454-528-6 | DOI: https://doi.org/10.1556/9789634545286
Ownership in times of water scarcity: are inhabitants supplied by private utilities consuming more water?
Authors: Sousa Cláudia Orsini Machado de , Fávero Luíz Paulo Lopes , Fouto Nuno Manoel Martins Dias
Published: February 2025

The growing public focus on water resource issues highlights the effectiveness of demand-side management in reducing water consumption, a strategy adopted worldwide. In Brazil, where water scarcity remains a concern, the 2020 regulatory framework accelerated water utilities' privatization. This study examines how the expanded role of private companies in the water and sanitation sector influences residential water consumption behaviors. Using a three-level hierarchical linear model, we analyzed per capita water consumption data from 858 Brazilian municipalities between 2002 and 2019. Results show that, on average, residents in municipalities served by private companies consume less water than those served by public providers. While rising tariffs from privatization may partially explain these outcomes, the literature offers mixed support for this claim. Nonetheless, findings emphasize the importance of state-owned water providers, which serve most Brazilians, in revisiting their water demand management strategies. Key actions could include informational campaigns and economic incentives to promote voluntary water-saving behaviors.
Evaluation of failings in urban water supply and sanitation systems in Sub-Saharan Africa: a systematic review to inform future planning
Authors: Agbo Chukwuemeka , Jeffrey Paul , Sule May N.
Published: February 2025

The high failure rate of water supply and sanitation (WSS) systems is a major concern, especially for developing countries. Using the Collaboration for Environmental Evidence guidelines, this study carried out a systematic review of literature on failings in WSS in the urban areas of Sub-Saharan Africa to identify the factors hindering sustainability as lasting coverage. There were 101 full-text articles examined and 21 articles included in the final review. The findings are discussed through the lens of the financial, institutional, environmental, technological and social (FIETS) framework and depicted in a causal loop diagram to visualize the system structure. In total, 37 factors that contribute to the failings of urban WSS systems across 14 Sub-Saharan African countries were identified. The root causes of failed or failing systems included a lack of stakeholder engagement in the planning and implementation; limited human resources capacity; limitations imposed by settlement type (informal settlements); insufficient funds, corruption and mismanagement of funds; and insufficient operation and maintenance of facilities. The study concludes that sustainability in the sector will involve the use of legal instruments, adequate planning techniques, anti-corruption and cost recovery mechanisms to ensure long-term financing.
Principio de Pareto y participación de los ciudadanos en la edición de artículos de entidades del Estado colombiano en Wikipedia
Authors: Llano Aristizábal Sergio , Peña Escobar Jennie
Published: February 2025

A los medios sociales se les atribuyen contribuciones al ejercicio de la democracia, tales como facilitar la expresión de las inquietudes y defensa de los intereses sociales, y el acceso a la información de interés público. A partir de la actividad de edición de los usuarios, este trabajo busca analizar los niveles de participación de los ciudadanos en la construcción de artículos de Wikipedia de entidades del Estado colombiano, y su contrastación con la distribución propuesta por el principio de Pareto. El estudio realizado consistió en un análisis descriptivo de datos abiertos. Los resultados apuntan a que existe participación limitada por parte de los ciudadanos, con una amplia concentración de la autoría en manos de muy pocos editores. Se abordan las implicaciones sobre el aprovechamiento de la inteligencia colectiva para la construcción colaborativa de este tipo de información pública como vía para la comprensión de las estructuras que nos gobiernan y los servicios a los que se tiene derecho.
Capital cultural y éxito académico de estudiantes migrantes en la educación media técnico profesional en la frontera norte de chile
Authors: Mondaca Rojas Carlos , Bustos González Raúl , Sánchez González Elizabeth
Published: February 2025

Se examina el rol del capital cultural de los estudiantes migrantes en la educación media técnico profesional en el norte de Chile y su influencia en el éxito académico. Se utilizó un enfoque de investigación cualitativo (entrevistas y grupos focales), identificándose un perfil del estudiantado migrante caracterizado por su esfuerzo, disciplina y un buen rendimiento. Se sostiene que su diversidad cultural podría ser un valioso capital que les brinda acceso a recursos y oportunidades, y les facilita el reconocimiento por parte de los docentes. Los hallazgos subrayan la necesidad de integrar este capital cultural en las políticas educativas, promoviendo así una educación inclusiva y de calidad.
KATECHEZA BIBLIJNA KS. ZBIGNIEWA MARKA SJ (1947-2024)
Authors: Kochel Jan
Published: February 2025

Celem artykułu było przedstawienie modelu katechezy biblijnej w ujęciu Zbigniewa MarkaSJ. Tego rodzaju katecheza ma prowadzić do tego, aby przemówił sam tekst biblijny, a jegowezwanie zostało usłyszane przez katechizowanych. Podstawowe cele i zadania katechezybiblijnej nawiązują do zasady przyjętej we współczesnej hermeneutyce, zgodnie z którą„tekst biblijny może właściwie zrozumieć tylko ten, kto sam przeżył to, czym mówi tekst”.Realizacja takiej katechezy jest możliwa, gdy katechetę wyróżniać będą trzy cechy, którymiodznaczał się krakowski jezuita: uwaga skierowana na osobę (katechizowanego),umiejętność rozeznawania (zdolność interpretacji i aktualizacji orędzia biblijnego) orazwrażliwość, polegająca na słuchaniu impulsów (wyczucia wierzących), które inni przeżywająwe wspólnocie Kościoła.
OD OSAMOTNIENIA DO OBDAROWANIA. TRUDNOŚCI A ROZWÓJ W NABYWANIU KOMPETENCJI SPOŁECZNYCH DZIECI
Authors: Światłoń Aneta , Szpoton Szczepan
Published: February 2025

Poczucie doświadczenia samotności przez małe dzieci i nastolatków pojawia się jakoproblem społeczny ze źródłami, dynamiką i konsekwencjami na tle społecznym i trybemwychowania dzieci. Stosuje się szeroki zakres definicji, aby pokazać różnorodność i przyczynyzaburzeń społecznych, na które narażone jest młode pokolenie. Autorzy wskazująna zdrowe relacje rodzinne, edukację przedszkolną i szkolną, przynależność do różnychgrup i społeczności, a także udział w inicjatywach społecznych jako czynniki prowadzącedo rozwoju kompetencji społecznych u dzieci i młodzieży. Wreszcie empatia i altruizm sąuznawane za cechy charakteryzujące wysokie kompetencje społeczne.
PRZYGOTOWANIE DO UCZESTNICTWA W SAKRAMENCIE POKUTY I POJEDNANIA
Authors: Przybylski Łukasz
Published: February 2025

Sakrament pokuty i pojednania jako sakrament uzdrowienia i powrotu człowieka do stanułaski uświęcającej jest stałym elementem formacji chrześcijanina. Nawrócenie i kształtowanieducha pokuty nie jest jednorazowym aktem, ale ma towarzyszyć człowiekowi przezcałe jego życie. Dlatego Kościół w sprawowanej liturgii oraz w swoim przepowiadaniunieustannie wzywa człowieka do nawrócenia i kształtowania sumienia w duchu Ewangelii.Szczególną grupą osób, która po raz pierwszy przystępuje do tego sakramentu są dzieci.Kościół podejmuje starania, aby człowiek został odpowiednio pouczony i przygotowany douczestnictwa w sakramencie pokuty i pojednania. Zazwyczaj przygotowanie do przyjęciasakramentów świętych dokonuje się w kontekście uczestnictwa w sakramencie Eucharystii.Jako przykład przygotowania dzieci do uczestnictwa w sakramencie pokuty i pojednaniaoraz Eucharystii zaprezentowałem formację dzieci w grupach barankowych. Współcześnie poszukuje się nowych form przygotowania do sakramentów i tych propozycji pojawia sięcoraz więcej. Pośród wielu wyzwań, jakie dzisiaj stoją przed Kościołem i wiernymi, pocieszającymi budzącym nadzieję jest fakt, że znajdują się tacy ludzie, a nawet całe rodziny,którzy poszukują rzetelnego i pogłębionego przygotowania do uczestnictwa w sakramentachKościoła.
Organic and inorganic fertilizers on growth and yield of Vigna radiata L. sown after wheat crop in Nawalparasi West, Nepal
Authors: Bhattarai Sagar , Shrestha Sailesh , Giri HomNath , Kafle Narayan
Published: February 2025

The purpose of this study is to know the effect of different organic and inorganic fertilizers on the growth and yield of mung beans cultivated after the harvest of wheat in the Nawalparasi district of Nepal. An experiment was carried out at Sarawal rural municipality, Nawalparasi West district, Lumbini Province during the summer season of 2023. In this experiment, five treatments were used. The treatments included: T1: Control, T2: NPK (0:20:20 kg.ha-1), T3: Recommended NPK dose (20:20:20 kg.ha-1), T4: Farm Yard Manure(FYM) (5 t.ha-1), and T5: Wheat residue (3 t.ha-1) incorporation. The experiment was laid out in a Randomized Complete Block Design to the above five treatments which were replicated four times with an area of each plot 2.4 m2. During this study period, the highest temperature recorded was 42.7 °C and the minimum temperature was 26 °C. Data on plant growth parameters like plant height, number of leaves, and yield parameters were measured. From the results, it was found that growth parameters like plant height at 15, 45, and 60 DAS and number of leaves at 60 DAS were significantly influenced by fertilizers treatment. Similarly, all the yield parameters like pods per plant, seeds per pod, 1000-grain weight, seed yield, and biological yield were significantly influenced by different fertilizers. All parameters showed better performance at NPK (20:20:20 kg.ha-1). Major growth parameters were highest at NPK (20:20:20 kg.ha-1) and lowest at control. Pods per plant, seeds per pod, 1000-grain weight (TGW), and harvest index were also higher in plots where the recommended dose of NPK fertilizer was applied. The maximum seed yield (0.71 t.ha-1) was found in NPK (20:20:20 kg.ha-1) than other treatments. Similarly, the harvest index of mung bean was the highest (25.39 %) in NPK (20:20:20 kg.ha-1) and the lowest in control (22.41 %). This concludes that the performance of major growth parameters and yield parameters were better under the recommended dose of NPK (20:20:20 kg.ha-1) fertilizer resulting in higher yield.
Perfil farmacocinético do tramadol e o-desmetiltramadol após administração intravenosa em jumentos (equus asinus)
Authors:   , Mouta Andressa Nunes
Published: February 2025

Os jumentos são animais rústicos que rapidamente se adaptam às condições adversas e ao intenso trabalho à tração, estando constantemente expostos a condições clínicas dolorosas e, por isso é de suma importância tratá-la adequadamente, por meio do uso de analgésicos apropriados. O tramadol é um analgésico opioide de ação central amplamente utilizado para tratamento da dor aguda e crônica em humanos e animais. Sua metabolização hepática resulta em diversos metabólitos, sendo o principal destes o metabólito ativo O-desmetiltramadol (M1), pois apresenta maior afinidade pelos receptores opioides. O objetivo do presente estudo foi descrever a farmacocinética do tramadol e do M1, após a administração intravenosa única de duas doses distintas em jumentos. Foram utilizados 8 asininos adultos, hígidos, machos e inteiros. Os 8 animais receberam a dose de 2 mg.kg-1 (T2) e 4 mg.kg-1 (T4) de tramadol, com intervalo de 15 dias entre os tratamentos. Foram coletados 10 ml de sangue da veia jugular para obtenção do plasma, realizados nos momentos 0 (antes da administração do fármaco) e seguindo os tempos: 5, 10, 20, 30, 40, 50 minutos, 1h, 1:15h, 1:30h, 1:45h, 2h, 2:30h, 3h, 4h, 6h, 8h, 12h, 24h e 48h. As amostras foram acondicionadas a -80°C para posterior análise farmacocinética por meio de cromatografia líquida de ultra eficiência acoplada a um detector de espectrometria de massas (CLUE-MS/MS), utilizando um modelo não compartimental. O tramadol e o M1 foram mensurados até 48 horas e quantificados até 12 horas após a administração. Os efeitos adversos decorrentes da administração do fármaco foram observados. A dose de 4 mg.kg-1 apresentou aumento significativo do tempo residual médio (TRM0→ ∞) e tempo de meia vida (t1/2) para o metabólito. Para o tramadol, a concentração plasmática máxima média (Cmáx), o t1/2 e TMR0→ ∞ para 2 mg.kg-1 foram de 473,62ng/ml, 4,49h e 1,44 h, enquanto na dose 4mg.kg-1 foram de 7553,93 ng/ml 5,99 h e 2,27 h. Para o M1, a Cmáx,t1/2, Tmáx e TRM0→ ∞ para a menor dose foram de 90,37 ng/ml, 2,50 h, 0,94 h e 3,88 h, enquanto para a maior dose foram de 109,62 ng/ml, 6,95h, 1,19 h e 7,42 h. Na menor dose, um animal apresentou ataxia e espasmos musculares, enquanto na maior dose, sete animais apresentaram esses efeitos. O tramadol e o M1 atingiram concentrações plasmáticas consideradas efetivas para analgesia. Sugere-se intervalo de administração de aproximadamente 2,5 e 6,9 horas para as doses de 2 e 4 mg.kg-1 respectivamente. Para evitar a ocorrência de efeitos adversos, é necessário administrar o fármaco em um tempo mais prolongado.
Efeitos de diferentes níveis de restrição alimentar sobre características do líquido ruminal de caprinos
Authors:   , Souza Francisco Jocelho Alexandre de
Published: February 2025

A caprinocultura é uma atividade bastante difundida no Nordeste brasileiro, onde predomina os sistema semiextensivo e extensivo de criação. A dificuldade em avaliar a qualidade e quantidade de volumoso ingerido dificulta a determinação do status nutricional dos animais criados nestes sistemas. A avaliação do líquido ruminal é uma ferramenta útil para identificar deficiências e doenças metabólicas, porém ainda é pouco explorada nesta espécie. Foram utilizados 25 caprinos castrados com 6 a 7 meses de idade, mantidos em baias coletivas e passaram por período de adaptação onde receberam alimento volumoso e concentrado além de água e sal mineral. O período experimental foi de 72 dias, e os animais divididos em 5 grupos de 5 animais e submetidos a restrição alimentar isoprotéica/hipoenegética e isoenergética/hipoprotéica em diferentes níveis. As amostras do liquido ruminal foram coletadas 7 vezes ao longo do período experimental utilizando sonda oro-gástrica semiflexível com aproximadamente 1,5 m de comprimento e 12 mm de diâmetro externo, lubrificado com óleo vegetal. As variáveis aferidas foram o pH, o tempo de redução ao azul de metileno (RAM), o tempo de sedimentação e flutuação (TAS) e a acidez titulável total (ATT) e o número de protozoários no líquido ruminal. apresenta. A restrição alimentar hipoproteica / isoenergética nos níveis de 20 e 40%, hipoenergética / isoproteica nos níveis de 20 e 40% e hipoenergética / hipoproteica no nível de 30% promoveram alterações na RAM, TAS, ATT e no número de protozoários nas características do líquido ruminal de caprinos criados em confinamento pelo tempo de 42 dias, no entanto essas alterações não foram capazes de causar danos as atividades do rúmen, dado que, os valores encontrados estiveram dentro dos padrões determinados para ruminantes.
Simulador didático de estimação fasorial e localização de faltas em linhas de transmissão trifásicas (self3∅)
Authors:   , Nascimento Cleydson Adller de Castro
Published: February 2025

A linha de transmissão é o equipamento do sistema elétrico mais propício a uma falta elétrica e normalmente, devido a sua grande extensão, encontra-se localizada em regiões distantes de centros urbanos e com mobilidade prejudicada. Com base nessas condições, utilizar algoritmos de localização apresenta-se como solução para identificar com precisão e velocidade o ponto de falta. A maioria dos algoritmos de localização emprega fasores medidos nos terminais da linha de transmissão, de forma que, para obtenção desses fasores são necessários métodos de estimação fasorial. O objetivo desse trabalho é desenvolver o Simulador Didático para Estimação Fasorial e Localização de Faltas em Linhas de Transmissão Trifásicas (SELF3∅) com o intuito de apresentar o desempenho de técnicas de estimação fasorial, bem como de diferentes algoritmos de localização de faltas, afim de se tornar uma ferramenta de apoio ao ensino dos cursos de engenharia elétrica. Além da plataforma interativa poder ser utilizada no processo de ensino-aprendizagem em cursos de engenharia elétrica, também oferece de forma rápida e concisa soluções gráficas e numéricas voltadas a estimação fasorial e localização de faltas, podendo também ser utilizado em pesquisas acadêmicas. Para validar o simulador didático construído, compara-se seus resultados juntamente ao software ATP em cinco cenários, para uma topologia voltada a medições com dois ou três terminais
Filtro de dados com redes neurais multinível para remoção deruídos na resposta de sensores baseados na ressonância Deplasmon de superfície
Authors:   , Batista Jackson Carlos Sousa
Published: February 2025

Sensores baseados na ressonância de plasmons superficie (SPR) são dispositivos comumente
utilizados para detectar interações moleculares, tais interações são classificadas por meio da
computação das características da curva SPR. A instrumentação utilizada nos sensores SPR
exige condições específicas para acoplamento de componentes óptico-eletrônicos, mecânicos
e fluídicos para a correta excitação dos plasmons de superfície. Ruídos inerentes a essa instrumentação
e do uso do sensor refletem-se na curva SPR, afetando a qualidade das características
extraídas. Através do processamento inteligente de dados, objetiva-se eliminar os principais
ruídos generalistas inerentes ao processo de análise com o uso de sensores SPR. Para isso, um
filtro-inteligente baseado em redes neurais artificiais multicamadas foi projetado. Denominado
de Neural Net SPR Filter (NNSF), o filtro foi acoplado a sensores SPR operando nos modos de
interrogação espectral (WIM) e angular (AIM). Para ampliar a capacidade de aplicação do filtro
implementou-se uma máquina de comitê que atua na redução da variância, sendo uma alternativa
para sistema com elevado nível de ruído. O NNSF, aproximou a resposta experimental à resposta
teórica com erro médio quadrático na ordem de 10􀀀5 e índices de correlação de modelo testado
acima de 90%, drenando a maior parte dos ruídos presentes durante os experimentos. Com
o uso do NNSF registrou-se melhor desempenho para o monitoramento da Largura, Energia,
Fase, Assimetria e Posição de ressonância (ângulo e comprimento de onda mínimos) das curvas
SPR. O filtro contorna ruídos devido a aspectos como rugosidade na camada de filme metálico,
imprecisão de ângulo e/ou comprimento de onda da luz incidente, além de remover oscilações
eletromagnéticas de amplitude e fase, devido a ausência de controle na temperatura e corrente da
fonte luminosa e do ambiente experimental. Desse modo, o NNSF demonstra-se uma alternativa
menos onerosa, evitando a substituição ou incorporação de novos componentes
The New Concept of Aswaja An-Nahdliyah Values: An Investigation of Religious Moderation and Citizenship Teaching in Pesantren-Integrated Schools
Authors:   Universitas Negeri Yogyakarta Indonesia, Ikhsan M. Alifudin , Marzuki Marzuki ,   Universitas Negeri Yogyakarta Indonesia, Suharno Suharno ,   Universitas Negeri Yogyakarta Indonesia, Khoirul Anam Faris ,   Universitas Negeri Malang Indonesia, Muzdalifah Zahrotul ,   STAI Ma'had Aly Al-Hikam Malang Indonesia, Arawindha Ucca ,   Universiti Kebangsaan Malaysia
Published: February 2025

This study aims to understand the implementation of the new concept of Aswaja an-Nahdliyah in teaching religious moderation and citizenship in pesantren integrated schools. It is based on the urgency of strengthening the role of pesantren in shaping a moderate understanding of religion and citizenship amid global challenges in the form of increasing radicalism and extremism. The research method used was a qualitative approach with a multi-site case study design. The research was conducted in three pesantren integrated schools in Malang Regency, East Java, which represent the types of salaf, modern, and semi-modern pesantren. Data were collected through deep interviews, participant observation, and document analysis. The results showed that the development of a new concept of Aswaja an-Nahdliyah was carried out through the systematic integration of values into the curriculum, the adoption of interactive teaching methods, and the development of teaching materials that integrate traditional values with contemporary issues. The teaching of Aswaja an-Nahdliyah values contributes significantly to the formation of religious moderation attitudes among santri, reflected in an increased understanding of key concepts of Islamic moderation and the ability to apply Aswaja an-Nahdliyah principles in responding to contemporary issues. This research provides valuable insights for the development of educational policies that promote religious moderation and strengthen civic values in Indonesia. It also makes an important contribution to the formulation of educational strategies that are adaptive to the demands of the times, while still maintaining the essence of fundamental Aswaja values
Politeness In The Digital Spotlight: Analyzing Language Use In Deddy Corbuzier's 'Close The Door' Podcast
Authors:   Universitas Brawijaya, Putri Helmaliya Erisa , Andarwulan Trisna ,   Universitas Brawijaya, Panich Pensri ,   Walailak University, Thailand
Published: February 2025

Language plays a crucial role in social communication, including on digital platforms such as YouTube. One of the most popular podcasts in Indonesia, "Close The Door" by Deddy Corbuzier, often showcases various forms of adherence to and violations of linguistic politeness. This study aims to describe the forms of adherence to and violations of politeness in the podcast using a cyberpragmatic perspective. The data source for this research is the video podcast "Close The Door," featuring a dialogue between Ivan Gunawan and Deddy Corbuzier titled "Cowo Kok Tas Cewe." This study employs a qualitative descriptive method, with data collection techniques conducted through documentation, observation, and note-taking. The data analysis procedure follows the stages outlined by Miles, Huberman, and Saldana, which include data collection, data condensation, data presentation, and conclusion drawing. Additionally, data triangulation in this study is based on sources, techniques, and time. The results indicate that violations of politeness in the podcast often take the form of jokes that lack respect for conversation partners and the use of vulgar language, reflecting a lack of attention to linguistic politeness.
Nurturing Character: A Comparative Study Of Elementary Education In Indonesia And Japan
Authors:   Universitas Negeri Malang, Dina Aulia Egi , Aji Saputro Bayu ,   Universitas Indonesia
Published: February 2025

Character education is crucial for addressing the negative impacts of technology on children's development. In this context, schools play a vital role in shaping individuals according to the norms and rules prevalent in society. This research aims to describe the efforts made in character development among elementary school students in Indonesia and to compare these efforts with those implemented in the Japanese education system. Through a literature study, this research explores the concrete steps taken by schools to improve character education.The findings indicate that support from the community, non-governmental organizations, and the government in Japan holds significant potential for adoption by schools in Indonesia. Several effective practices identified, such as integrated approaches and community support, can enhance the quality of character education in elementary schools. By implementing these methods, it is expected that schools in Indonesia can produce students who are not only academically intelligent but also possess good moral values and social responsibility. The role of school leaders is crucial in ensuring effective character education by managing the available support and resources to achieve these goals.
Zaburzenia w zakresie masy ciała i ich wpływ na poziom zadowolenia z życia w grupie młodzieży
Authors: Chłędowska Milena
Published: February 2025

Wstęp. Zadowolenie z życia traktowane jest jako jeden z najbardziej istotnych wskaźników prawidłowego przystosowania do życia. Okres ryzyka rozwoju zaburzeń jedzenia – adolescencja, bardzo często towarzyszą temu zaburzenia/ wahania nastroju. Dziecko z zaburzeniem masy ciała jest rozdrażnione, mniej skupione oraz narażone na dezaprobatę rówieśników. Jak wiemy dzieci są znane ze swojej ciekawości świata oraz dużą szczerością w wypowiadanych słowach, często nie zastanawiają się nad wypowiedzianymi słowami i nie mają problemu, aby skomentować wygląd swoich koleżanek lub kolegów. Poziom zadowolenia z życia wśród młodzieży może być ściśle związany z zaburzeniami masy ciała.
Cel. Celem pracy jest analiza poziomu zadowolenia z życia młodzieży w wieku szkolnym z zaburzeniami w zakresie masy ciała.
Materiał i metody. W pracy wykorzystano metodę sondażu diagnostycznego przy użyciu ankiety własnego autorstwa oraz metody szacowania, wielu badań w celu uzyskania ogólnych wniosków.
Wyniki. Grupa osób z nadwagą i otyłością ocenia najniżej zadowolenie z jakości życia w aspekcie zdrowia fizycznego. Według badań własnych nie ma istotnych statystycznie różnic w poziomie energii między różnymi kategoriami wagi. Waga prawidłowa i nadwaga mają wpływ na częstotliwość spędzania czasu ze znajomymi, a osoby z niedowagą wykazują niższą aktywność społeczną. Analiza nie wykazała statystycznie istotnych różnic między płciami oraz wiekiem, a poziomem zadowolenia ze życia.
Wnioski. Poziom masy ciała wpływa na młodzież w aspekcie zdrowia fizycznego w znacznym stopniu u dzieci z niedowagą, a w największym u dzieci z nadwagą. Młodzież z nadwagą ma największe problemy w obszarze zdrowia psychicznego względem masy ciała. Dzieci z niedowagą oraz nadwagą wolą czas spędzać w domu, czując się komfortowo w swojej przestrzeni. Dane demograficzne badanej młodzieży nie różnicują ogólnego poziomu jakości życia, płeć czy też wiek nie ma wpływu na jakość życia młodzieży.
Wspierająca, opiekuńcza i edukacyjna rola pielęgniarki wobec pacjenta pediatrycznego z zespołem FAS – studium indywidualnego przypadku
Authors: Czyżewska Justyna
Published: February 2025

Wstęp. Spożywanie alkoholu w ciąży może powodować nieodwracalne uszkodzenia organizmu dziecka i prowadzić do tzw. zespołu alkoholowego płodowego (FAS, Fetal Alcohol Syndrome) charakteryzującego się wieloma trwałymi defektami rozwojowymi, zarówno neurologicznymi, jak i fizycznymi, które niosą potem ogromne trudności dla dziecka przez jego całe życie.
Cel. Celem niniejszej pracy jest rozpoznanie problemów pielęgnacyjnych i wskazanie zadań pielęgniarki wobec pacjenta pediatrycznego z zespołem FAS.
Prezentacja przypadku. Pacjent, mający 7 lat i 6 miesięcy, został przyjęty do oddziału w celu przeprowadzenia badań kontrolnych z powodu limfadenopatii, będący jednocześnie pacjentem ze stwierdzonym zespołem FAS. W dniu przyjęcia jego stan był dobry. Aktualnie od kilku dni pacjent skarży się na duszność, a w dniu przyjęcia notowano gorączkę o temperaturze 38˚C. Dodatkowo dziecko często odmawia spożycia posiłków, a po zjedzeniu zupy mlecznej wystąpiła biegunka. Pacjent posiada założoną kaniulę obwodową umieszczoną na prawej dłoni. U dziecka pojawiają się objawy autoagresji, takie jak budzenie się w nocy i uderzanie głową w barierki łóżka, oraz stany depresyjne. Dotychczasowe obserwacje wskazują, że dziecko nie wypowiada się. Ze względu na powyższe, stan pacjenta wymaga ciągłej obserwacji. Mimo pobytu w placówce opiekuńczej, na oddziale będzie pojawiać się matka pacjenta, która potrzebuje edukacji w zakresie opieki nad dzieckiem cierpiącym na duszność i przejawy autoagresji.
Wnioski. Pielęgniarka sprawująca opiekę nad dzieckiem z alkoholowym zespołem płodowym zobowiązana jest do uważnego i stałego monitorowania stanu zdrowia pacjenta oraz jego odpowiedzi na zastosowane leczenie i zastosowane techniki pomagające mu prawidłowo funkcjonować. Wymagane jest całościowe oraz indywidualne podejście wobec pacjenta, ale także wprowadzenie konkretnej edukacji wobec opiekunów chorego dziecka.
Straty i marnowanie żywności – charakterystyka problemu oraz sposoby przeciwdziałania skali zjawiska
Authors: Zborowski Marek , Mikulec Anna , Wygoda Małgorzata , Wojtas Zuzanna , Magiera Agnieszka , Kruczek Katarzyna
Published: February 2025

Wstęp. Straty i marnowanie żywności stanowią poważny problem XXI wieku. Ilość traconej żywności przekracza obecnie potrzeby wyżywienia krajów borykających się z brakiem możliwości zabezpieczenia potrzeb żywieniowych społeczeństwa krajów szczególnie rozwijających się. Konsumenci rozpatrują marnowanie żywności jako poważny problem zarówno pod względem etycznym i społecznym jak również środowiskowym i ekonomicznym, jednak mimo to blisko 1/3 światowej produkcji żywności na świecie jest marnowana.
Cel. Celem pracy było przedstawienie skali problemu strat i marnowania żywności oraz sposobów ograniczenia skali problemu.
Materiał i metody. Metoda zastosowana w pracy to analiza literatury dotyczącej strat i marnowania żywności.
Przegląd. Problem z marnowaniem żywności jest zróżnicowany i związany z licznymi czynnikami począwszy od poziomu dochodów, ograniczeniami technicznymi oraz technologicznymi związanymi z infrastrukturą i transportem, aż po zachowania i postawy konsumentów. Duża część strat i marnowania żywności ma miejsce już w chwili zaopatrywania się w produkty żywnościowe. Zakup zbyt dużej ilości żywności może generować straty związane z upływem terminu przydatności do spożycia. Drugim poważnym problemem związanym z nadprodukcją żywności jest przygotowanie zbyt dużych porcji żywności, które nie mogą zostać skonsumowane czego konsekwencją jest ich marnowanie.
Wnioski. Istotnym czynnikiem determinującym korzystne zmiany w zakresie ograniczania strat i marnowania żywności powinna być edukacja na temat zwiększania świadomości na temat bezpieczeństwa żywności oraz przedstawienie możliwości racjonalnego zarządzanie żywnością.