bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterización de cambios didácticos en la práctica docente universitaria de química organometálica
Authors: Cárdenas-Acero Alexander , Mosquera Carlos J. , Baquero Edwin A.
Published: January 2025

En este trabajo se presenta el primer estudio de la caracterización de los cambios didácticos en la práctica docente de un profesor universitario de química organometálica, en relación con la inclusión de la naturaleza de la ciencia en su quehacer educativo y su conocimiento didáctico del contenido. Para ello, se adoptó un enfoque multiparadigmático y plurimetodológico y se llevó a cabo un proceso de reflexión con el docente a lo largo de un año académico, a través de espacios de discusión conjunta. La implementación de otros instrumentos de recolección de datos, como entrevistas y observaciones de clase, complementó la información recolectada en las sesiones de trabajo. Debido a la emergencia provocada por el COVID-19, la intervención se llevó a cabo de manera virtual. Los datos obtenidos fueron analizados en términos de las categorías de trabajo propuestas. Entre los resultados, se destaca la comprensión de la reflexión de la práctica como un proceso esencial en el quehacer docente (actitudinal), la aparición de formas alternativas de explicación (procedimental), y el reconocimiento de la importancia de abordar el conocimiento histórico dentro del aula (conceptual). Sin embargo, a pesar del proceso implementado, el profesor no mostró interés en las posturas de la filosofía de la ciencia, lo cual concuerda con trabajos anteriores.
Metamodelización en un aula de física universitaria: visiones del estudiantado sobre los modelos científicos
Authors: Useche-Arciniegas Víctor Julio , Rodríguez-Pineda Diana Patricia , Adúriz-Bravo Agustín
Published: January 2025

Algunos resultados de investigación en didáctica de las ciencias dan a conocer que la incorporación de los modelos científicos en la enseñanza y aprendizaje de las ciencias es escasa, más aún en la actividad científica escolar universitaria. Por ello, el objetivo de esta investigación es analizar el involucramiento del estudiantado de una clase de física universitaria en actividades de metamodelización, dirigidas a que comprendan la naturaleza e importancia de los modelos científicos. El proceso investigativo se realizó desde el paradigma interpretativo con enfoque cualitativo, en el marco de una intervención didáctica implementada con 24 estudiantes matriculados en la asignatura de Física Mecánica, orientada por uno de los investigadores en la Universidad Francisco de Paula Santander, ubicada en Norte de Santander, Colombia. Para la recolección de la información, se realizó una intervención de aula que se desarrolló en cuatro fases: exploración de las ideas iniciales de los estudiantes sobre noción de modelo científico, implementación del artefacto didáctico, ajuste de los mapas mentales construidos inicialmente y realización de entrevistas. El análisis de los datos reveló que, inicialmente, algunos estudiantes relacionaban el modelo científico con unos estándares o pasos, es decir, con una forma de investigar. Además, manifestaron que no conocían la importancia de los modelos científicos en la enseñanza de las ciencias.
La investigación formativa para la enseñanza de la ciencia y la tecnología en la escuela
Authors: Valderrama-Alarción Camilo Andrés , Guerrero-Villalobos Liliana Rocío , Lache-Rodríguez Luz Mary
Published: January 2025

La investigación formativa (IF) es una estrategia pedagógica que tradicionalmente ha estado asociada a la formación universitaria, sin embargo, desde hace un par de décadas está siendo implementada a nivel de educación básica y media para la enseñanza de la ciencia y la tecnología, sin que hasta el momento existan suficientes estudios acerca de sus potencialidades y de cómo está siendo desarrollada y apropiada por los docentes de estos niveles educativos. En este artículo de investigación se realiza un análisis acerca de la implementación de la IF en algunas instituciones educativas oficiales de educación básica y media en el Departamento de Cundinamarca y Bogotá D. C., Colombia. Es un estudio cualitativo desde un paradigma interpretativo, en el que se identificaron y reconocieron junto con los maestros elementos relevantes en sus prácticas en relación con la if: sus implicaciones para el rol del maestro y su quehacer, el carácter interdisciplinar de las líneas temáticas trabajadas y las dinámicas de gestión institucional para trabajar bajo esta estrategia. Desde los resultados es posible evidenciar que, en la escuela la IF toma un carácter más amplio que la definición tradicional del investigar desde las prácticas o el investigar investigando, porque además de promover el ejercicio de la lógica del proceso investigativo, también permite llevar a la práctica procesos de innovación pedagógica que articulan el reconocimiento de contextos, fortalecimiento de competencias, el trabajo inter y transdisciplinar en ciencias y tecnología y la gestión de proyectos escolares orientados a la transformación social en los territorios.
Possibilidades didáticas do cinema em sala de aula: educação em saúde e negacionismo científico
Authors: DaSilva Pauletti Eloisa , Gonçalves dos Santos Eliane
Published: January 2025

Esse artigo apresenta o potencial do filme Sonhos Tropicais como instrumento pedagógico capaz de desencadear a elaboração de materiais didáticos por professores de Ciências Biológicas em formação inicial. Metodologicamente, a pesquisa fundamentou-se na análise microgenética, tendo como sujeitos licenciados/as em Ciências Biológicas de uma Instituição de Ensino Superior (ies). Os dados de análise consistiram em episódios de transcrições de interações e nos materiais didáticos produzidos pelos licenciandos/as. Como resultado, identificamos duas cenas, sendo que a cena 1 contou com dois episódios para análise. Para as discussões, a pesquisa baseou-se na abordagem histórico-cultural proposta por Vigotski. Este estudo evidencia o papel didático do cinema como instrumento pedagógico em sala de aula, onde sua intencionalidade se reflete em atividades com diferentes temas relacionados à Educação em Saúde. Concluímos, por tanto, que o uso do cinema com uma intencionalidade pedagógica no ensino possibilita discussões sobre diferentes assuntos, como alfabetização científica, saúde pública, Infecções Sexualmente Transmissíveis (ist), a vida e obra de Oswaldo Cruz, a pesquisa no Brasil, a Campanha nacional de vacinação e a história do Zé Gotinha. Esses instrumentos culturais auxiliam no desenvolvimento das funções psicológicas superiores, e, diante dos contextos vivenciados e a intencionalidade pedagógica com que são utilizados, é possível formar sujeitos críticos e atuantes na sociedade.
Diseño y validación de un instrumento para indagar concepciones sobre razas humanas, esencialismo y biología
Authors: Pérez Gastón , González-Galli Leonardo , Bifano Fernando
Published: January 2025

La cuestión racial suele ser estructural en nuestras sociedades. En relación con la enseñanza, conocer las concepciones sobre la relación entre raza y biología que sostienen los estudiantes permitirá elaborar estrategias acordes para intervenir en este tema tan complejo. En este artículo presentamos un cuestionario, junto con su validación, que permite recolectar información sobre las concepciones de estudiantes de profesorado y docentes en ejercicio sobre la cuestión de las razas o etnias humanas. Además, permite identificar algunos supuestos esencialistas asociados a estas concepciones. Para validar el cuestionario se utilizó una muestra de 552 docentes formados y en formación en el área de biología y ciencias sociales, así como del juicio de once expertos. Se realizaron análisis de consistencia interna y análisis factorial exploratorio. Consideramos que este cuestionario será de importancia para la investigación en didáctica, dado que las concepciones de raza suelen impactar en la manera en que se aborda la temática del racismo en las clases de biología.
El COVID-19: investigación de educación en ciencias y aportes para trabajo de aulas
Authors: Hernández-Hernández María del Rocío , Gómez-Galindo Alma Adrianna
Published: January 2025

Desde una mirada compleja, exploramos cómo se podría abordar el contenido de la pandemia por COVID-19 en las aulas de educación básica. Para responder a este interrogante, se realizó una revisión documental de literatura especializada con un corpus de veinticinco textos. Los resultados apuntan a la distinción entre los conceptos de infección y pandemia para esclarecer las esferas sociales, políticas y económicas que esta última engloba. Se posicionan la combinación de múltiples modelos, la multirreferencialidad y las controversias sociocientíficas como marcos clave para el desarrollo de esta mirada compleja en las aulas. Se discuten cinco dimensiones sociales que son abordadas en estos artículos. Esta revisión forma parte de una investigación más amplia en la que se analiza el tratamiento de la pandemia en el currículo y el aula en el contexto mexicano de reforma educativa actual, por lo que discutimos el reto de concretar estas ideas en las aulas.
Prácticas interculturales de enseñanza de las ciencias para la inclusión cultural
Authors: Tovar-Gálvez Julio César
Published: January 2025

El profesorado de ciencias necesita apoyo didáctico para llevar la inclusión cultural al aula. Hay políticas, teoría y conciencia sobre la diversidad y la inclusión cultural, pero el profesorado necesita aprender a implementarlas. Una solución son las Prácticas Interculturales de Enseñanza de las Ciencias (piec) para incluir diversas epistemologías en el aula. Metodológicamente, la investigación basada en el diseño guía el desarrollo de las piec a través de tres ciclos iterativos. El resultado es una piec de planificación y otra de implementación. En conclusión, la evidencia demuestra que la profesora guía al estudiantado a construir explicaciones desde diversas epistemologías.
Intereses de los profesores en formación posgradual, una mirada desde el CDC en química
Authors: Delgado-Jiménez Jose Armando , Ariza-Ariza Leidy Gabriela
Published: January 2025

Este artículo de investigación refleja las tendencias en didáctica de la química de un programa posgradual especializado en didáctica, a la luz de las categorías Enseñanza, Energía, Formación de profesores, Ambiental e Historia y epistemología de la química. Se utilizó como herramienta el software Nvivo para la clasificación y sistematización de la información documental. Se identificaron algunos aspectos que movilizan las investigaciones didácticas en química a partir del análisis de investigaciones de un programa posgradual reconocido, donde ingresan profesionales de diferentes enfoques que se dedican a la enseñanza de la química tanto en la universidad como en instituciones escolares. El análisis de estas investigaciones se realizó desde la mirada del Conocimiento Didáctico del Contenido (CDC) en química y su influencia en el contexto de enseñanza. Entre los resultados obtenidos se destaca el interés de los investigadores por indagar en los procesos formativos en la educación media, lo cual va en dirección con las tendencias investigativas del programa. Se encontró que los aspectos más trabajados se relacionan con el desarrollo de competencias científicas, fortalecimiento de habilidades argumentativas en las ciencias naturales-química, alfabetización científica, estimulación y desarrollo del pensamiento crítico, integración y reformulación de los contenidos químicos.
A conservação patrimonial como auxiliar na mitigação dos efeitos climáticos
Authors: Teixeira Bruna Correia , Costa Lorena Vila Bela , Monteiro Eliana Cristina Barreto , Melo Alcília Afonso de Albuquerque e
Published: January 2025

When reflecting on the benefits of conserving architectural cultural heritage and reusing pre-existing buildings to mitigate the effects of climate change, which are favored by civil construction activities, this article sought to present solutions to resolve the existing damages in the Luiz Nunes Pavilion, built in Recife, in 1937, under the precepts of modern architecture developed by Le Corbusier. To this end, the research was divided into three moments: construction characterization, prepared using the Dimension Analysis method; diagnosis, developed with the aid of maps and damage identification sheets and based on visual inspections carried out on site; and conduct, which encompass proposed actions aiming at less intervention in the property and greater compatibility between the original techniques and materials. The diagnosis and suggested guidelines, of proven effectiveness and easy execution, ensure the feasibility of resuming the use of the Pavilion, providing the population of Recife with another space with which to establish links and create new meanings for their identity, in addition to reducing the environmental impacts generated by the demand for new construction.
Ondas de calor
Authors: Marques Luis Otavio do Amaral , Meireles Eduardo , Jorge Nayara Luciana , Rosa Jean Lucas , Oliveira João Paulo Leonardo de
Published: January 2025

In the context of climate change, many efforts have been made to avoid or mitigate its effects. Extreme weather events such as heatwaves have become more frequent and intense worldwide, causing complications to human health, besides other environmental and socioeconomic imbalances. Thus, this article conducts a current bibliographical and documental review in order to define heatwaves, highlight the use of the Heat Index to quantify thermal perception, and evaluate their harmful effects. It was found that the greatest health risk occurs in the elderly and in individuals with weakened circulatory and respiratory systems. Other indirect consequences include insect proliferation, contamination of groundwater, changes in agricultural production, the need for adjustments in psychotropic and antihypertensive medication dosages, interruptions in transportation and power supply systems, and an increase in work accidents.
USDA LTAR Cropland Common Experiment: Standardized primary metric protocols v1
Authors: J. Abendroth Lori , A. Liebig Mark , Philip Robertson G
Published: January 2025

A component of the USDA ARS Long-Term Agroecosystem Research (LTAR) network is a Common Experiment standardized across all sites. In this overview protocol we describe the development of standardized protocols for the biophysical metrics collected in the Common Experiment. Throughout this collection, we refer to “metric” as the physical sample that can be quantified and used to inform the status of performance indicators within production, environment, economic, and society domains. We refer to “protocol” as the methods used to collect that metric so that all experimental sites are compatible. This set of protocols were developed for the Cropland Sites although some are also usable for Grazingland and Integrated Common Experiment Sites. This collection allows the LTAR network to ensure research is scalable and robust. All Cropland Common Experiment Sites within the network started following these protocols with the 2024 growing season.
Protocolo para a Quantificação de Cafeína, Ácido Clorogênico, Mangiferina e outros por HPLC-DAD v2
Authors: M. Borges Ricardo
Published: January 2025

Este protocolo é adequado para a análise de compostos bioativos como cafeína, ácido clorogênico, mangiferina e outros em matrizes como extratos vegetais. O método utiliza HPLC acoplado a um detector de arranjo de diodos (DAD). English: This protocol is suitable for the analysis of bioactive compounds such as caffeine, chlorogenic acid, mangiferin, and others in matrices like plant extracts. The method employs HPLC coupled with a diode array detector (DAD).
Listening Strategies Utilized by Thai EFL Students for Comprehending ASEAN Englishes-Accented Conversations
Authors: Yaemtui Wachirapong
Published: January 2025

Listening is widely regarded as an essential language skill for achieving proficiency in both educational and professional contexts. Despite its significance, listening comprehension remains one of the most challenging tasks for language learners, especially in the context of non-native English accents. According to numerous scholars, the ability to select and apply appropriate listening strategies is crucial for successful listening comprehension. Therefore, this study aims to investigate how Thai EFL students, categorized as high-ability and low-ability listeners, utilize cognitive and metacognitive listening strategies to comprehend Association of Southeast Asian Nations (ASEAN) Englishes-accented conversations. In this regard, 300 participants were required to report their perceived use of listening strategies through a questionnaire adapted from the Strategy Inventory for Language Learning (SILL), followed by verbally explaining their use of these strategies in detail through a think-aloud task. The findings indicate that the high-ability listeners significantly employ overall listening strategies more frequently than the low-ability listeners. More importantly, the high-ability listeners demonstrate a greater awareness of which strategies to use and how to apply these strategies in a systematic way to successfully achieve comprehension of ASEAN Englishes-accented conversations. Based on these findings, Strategies-Based Instruction (SBI) is recommended as an instructional approach to help low-ability listeners effectively and appropriately utilize practical listening strategies to improve their comprehension of conversations involving non-native English accents.
Ecolexicon of Flora and Fauna in Makassarese Proverbs: An Ecolinguistic Study
Authors: Umiyati Mirsa , Asfar Nur Afnita , Sari Rika Purnama
Published: January 2025

This study is aimed at examining the Flora and Fauna ecolexicon in the Makassarese language and understanding the metaphorical relationships within the analyzed ecolexicon using Haugen’s (1972) theory. The study employs a qualitative approach. The research data is sourced from documents. The results reveal the existence of 20 flora ecolexicons and 20 fauna ecolexicons, comprising linguistic morphology and biotic semantic morphology categories. The metaphors used by the Makassarese community fall into the conventional classification of Makassarese discourse society’s agreement. The interdependence between flora and fauna that inhabit the Makassar natural environment (ecoregion) serves as the realm of sources interacting with humans. This interaction is connected to their conditions and behaviors as the target domain through a correlated cross-mapping process within the mental and cognitive realms of the discourse community members. This is subsequently realized in Makassarese proverb and in verbal communication within the social life of the discourse community. The ecolexicons, based on the ecophilosophical perspective within eco-linguistics, hold philosophical values. The intended philosophical values encompass local wisdom, consumptive value, productive value, and environmental service value.
Measuring Vocabulary Knowledge for Secondary Graduate Students
Authors: Alsuhaibani Yasser
Published: January 2025

This study examines the extent of vocabulary knowledge among Saudi students who have recently graduated from secondary school, and its potential connection to their performance in English. The study involved 83 participants taking the Updated Vocabulary Levels Test by Webb et al. (2017). The findings reveal that the mean score of the test is below expectations: minimum scores suggested by Webb et al. (2017) are 29/30 for the first three word levels (1,000, 2,000, and 3,000) and 24/30 for the last two word levels (4,000 and 5,000). However, the average scores for participants in the study are 22.6/30 for the 1,000-word level, 16.4/30 for the 2,000-word level, 9.3/30 for the 3,000-word level, 8.9/30 for the 4,000-word level, and 7.7/30 for the 5,000-word level. These low scores could indicate an inadequate performance in English and imply that participants will struggle with receptive and productive skills. Therefore, a thorough evaluation of the EFL curriculum from K-12, especially for teaching vocabulary, is strongly recommended. Moreover, the adequacy of learners’ vocabulary knowledge will be a crucial boost for their performance in communicative tasks.
Implementing a Genre-Based Approach to Enhance Essay Writing Skills in Saudi EFL Learners
Authors: Alhammad Albandary Ibrahim
Published: January 2025

This study investigates the impact of explicit instruction in writing using a genre-based approach (GBA) on Saudi EFL students. It examines emergent themes derived from learner interviews and assesses teachers' awareness of employing this pedagogical approach. Conducted at Prince Sattam bin Abdulaziz University (PSAU), the mixed methods study involved 32 EFL learners and 4 teachers from the BA program. A specifically designed intervention aimed to train teachers in genre-based essay writing instruction. Results indicate a significant improvement in students' writing performance, with scores increasing from 12.97 in the pretest to 14.90 in the post-test (Sig. = .000). Students reported heightened confidence in utilizing GBA for writing, while teachers displayed a positive disposition towards adopting efficacious methods to enhance student writing skills, despite potential gaps in their knowledge of recent developments in ELT.
Expanding English Learning Beyond Classroom Boundaries: Investigating EFL Students’ Perceptions of the Effects of Listening to Online Stories on Incidental Vocabulary Acquisition
Authors: Al-Othman Amal Abdul-Aziz Mohammad
Published: January 2025

This study investigated EFL students’ perceptions of how listening to online stories impacts incidental vocabulary acquisition. Conducted at an English department at a public university in Riyadh, Saudi Arabia, the research examined cognitive processes and assessment methods related to vocabulary learning, including dynamic and self-assessment. Quantitative results showed that listening to online stories significantly improved incidental vocabulary acquisition, with a mean score of 3.59 ± 0.84. About 89.8% of students reported enhanced vocabulary, covering aspects such as word recognition, formation, and usage, while 84.2% observed better word recognition in different contexts. Additionally, 80% of students found that online stories were more effective than reading for increasing vocabulary knowledge. Self-assessment also played a significant role in understanding vocabulary acquisition processes, with a mean score of 3.70 ± 0.90. Qualitative results identified six key methods for assessing vocabulary acquisition: dynamic assessment, technology-based tools, vocabulary tests, self-assessment, vocabulary journals, and storytelling assignments. Vocabulary journals were identified for their effectiveness in developing cognitive skills, functional vocabulary use, and contextual understanding, and reinforcing retention through repetition. The study underscores the benefits of online stories for authentic vocabulary learning and suggests incorporating modern methods, such as mobile applications, to extend English learning beyond the classroom.
Integrating Blockchain and AI to Enhance Supply Chain Transparency in Energy Sectors
Authors: Talla Rajasekhar Reddy
Published: January 2025

This research examines how Blockchain and AI might improve energy supply chain transparency. These technologies are discussed to solve energy supply chain inefficiencies, fraud, and transparency while encouraging sustainability and operational optimization. The paper evaluates Blockchain and AI applications in energy systems using secondary data from literature, case studies, and industry sources. In summary, Blockchain provides an immutable and decentralized ledger for transparency and data integrity, while AI improves operational efficiency via predictive analytics, demand forecasting, and asset management. These technologies provide real-time tracking, cost reduction, and renewable energy integration. Scalability, data integrity, and regulatory ambiguity remain issues for Blockchain. The paper also stresses the need for clear legislative frameworks to govern energy industry blockchain and AI deployment. Policymakers should stimulate innovation, invest in digital infrastructure, and set safe and efficient technology integration standards. The study shows that Blockchain and AI can transform energy supply chains by improving transparency, efficiency, and sustainability and solving sector issues.
Characteristics and findings of digital subtraction angiography and magnetic resonance imaging in neurological patients: a cross-sectional study
Authors: Sumantri Fritz , Adriani Dini , Novitasari Ratih W. , Lomboan Veinels C. , Kurnia Leny , Kastilong Merlin P.
Published: January 2025

Background: Stroke is a major health concern worldwide with significant rates of mortality and morbidity. Asian population suffers from increasing incidence of stroke. Various imaging modalities have been developed for the diagnosis of stroke and neurological diseases. This study aims to compare the use of digital subtraction angiography (DSA) and magnetic resonance imaging (MRI) in neurological patients, underscoring particularly in ischemic stroke patients.
Methods: This cross-sectional descriptive study was performed from February to November 2023. Data was taken from medical records. All patients visiting the outpatient care unit of a hospital in Jakarta who underwent DSA and MRI were included in the study. The data taken included the patient’s name, medical record number, age, gender, MRI results, DSA results, and diagnosis. Diagnosis was established through history taking and physical examination.
Results: Of 500 subjects included in the study, most subjects were male (50.6%) aged 20 – 60 years old (75.6%) abnormal MRI and DSA results (84.6% and 90.6%, respectively). Ischemic stroke was the leading diagnosis (50.8%). MRI and DSA results showed 79.6% agreement of all cases.
Conclusions: Although MRI showed normal results, DSA could show abnormal results. This points out DSA superiority in detecting vascular abnormality compared to MRI.
Homicidal deaths due to weapons: an autopsy-based study
Authors: Hossain Din Islam , Jeba Tasfia Razzak , Dey Suranjit , Tasnim Zakia , Tabassum Taniza
Published: January 2025

Background: Homicide, one of the oldest crimes in human civilization, involves the killing of one human being by another. Defined legally as the intentional destruction of human life, it is a leading cause of unnatural deaths worldwide. The crime involves two key elements: Mens rea (preplanning) and Actus reus (execution). Homicidal methods and patterns vary globally, influenced by factors such as weapon availability, motives, cultural and social influences, and socio-economic status. Violence is recognized as a global public health issue, contributing to significant mortality and disability, with approximately 520,000 people dying annually from interpersonal violence. The study aims to explore the types of injuries, weapons, and anatomical regions of the affected victim.
Methods: This retrospective observational study was conducted at the department of forensic medicine, Dhaka medical college and hospital, Dhaka, Bangladesh, focusing on 120 autopsied homicide cases involving definite weapons from January 2021 to December 2023. The study included all age groups, excluding accidental burn deaths, suspected homicidal poisonings, and decomposed bodies. Data were gathered from police inquest and post-mortem reports, analyzing injury types, weapons used, and their anatomical distribution. The findings were correlated with victims' age and gender. The ethics committee approved the study, and data were presented using SPSS for statistical analysis.
Results: The study analyzes violent incidents, focusing on participant demographics, weapon types, injury patterns, and homicide intentions. The highest participant age group is 21-30 years (33.33%), with males dominating at 84.17%. Knives are the most used weapon (51.67%), followed by blunt objects (38.33%). Head injuries are most common (44.17%), with intracranial hemorrhage (ICH) as the leading cause of death (48.33%). Non-intentional homicides constitute 60%, while 35.83% are deliberate. The study provides detailed insights into the nature and causes of homicides in the population studied.
Conclusions: The study in Dhaka, Bangladesh, reveals that young males are the primary victims of homicide, with knives and blunt objects frequently used. Head injuries, especially ICH, are the leading cause of death. The findings call for targeted interventions and further research into the factors driving non-intentional homicides.
A comparative analysis of adiponectin and soluble CD36 levels between diabetic and non-diabetic metabolic syndrome patients
Authors: Khan Mansura , Alam M. Sohrab , Siddiquee Nadia , Nur Jesmin , Rahman Zeenat Farzana , Moniruzzaman Mohammad
Published: January 2025

Background: Metabolic syndrome refers to a constellation of interrelated metabolic risk factors that promote the development of type-2 diabetes mellitus (T2 DM) and cardiovascular diseases (CVD). The purpose of this study was to compare the serum levels of adiponectin and soluble CD36 between diabetic and non-diabetic metabolic syndrome patients. The aim of this study was to compare the serum levels of adiponectin and soluble CD36 between diabetic and non-diabetic metabolic syndrome patients.
Methods: This cross-sectional analytical study, conducted at the Outpatient Department and Department of Immunology at BIRDEM General Hospital over 12 months, included 80 participants: 60 with metabolic syndrome (30 type-2 diabetic and 30 non-diabetic) and 20 healthy controls. Participants underwent clinical examinations, anthropometric measurements and blood tests for serum analysis of adiponectin and soluble CD36 using ELISA and immunonephelometry. Data were analyzed using nonparametric tests (Mann-Whitney U test, Levene's test) and correlation analyses (Pearson and Spearman) with p<0.05, using SPSS version 20.
Results: Metabolic syndrome patients had higher weight, BMI, waist circumference and blood pressure compared to healthy subjects. Adiponectin and soluble CD36 levels were significantly lower in metabolic syndrome patients, with differences between diabetic and non-diabetic groups. Adiponectin negatively correlated with waist circumference, blood pressure and triglycerides, while soluble CD36 positively correlated with waist circumference, diastolic blood pressure and triglycerides.
Conclusions: In conclusion, our study highlights that adiponectin and soluble CD36 levels are significantly altered in diabetic versus non-diabetic metabolic syndrome patients, suggesting their potential as biomarkers for metabolic syndrome.
Response of dasatinib in different phase of chronic myeloid leukaemia patients
Authors: Begum Moshammat Naznin , Khan M. A. , Ara Tasneem , Biswas Akhil Ranjon , Akter Mafruha , Islam M. Manirul , Nazneen Humayra , Farhad Muhammad Nurul
Published: January 2025

Background: Chronic myeloid leukemia (CML) is a stem cell disorder caused by a chromosomal abnormality that results in the formation of the Philadelphia chromosome. This abnormality leads to the production of the Bcr-Abl tyrosine kinase, which drives the uncontrolled proliferation of cells. Imatinib, a tyrosine kinase inhibitor (TKI), revolutionized the treatment of CML, but resistance and intolerance in some patients have necessitated alternative therapies such as Dasatinib, a potent multitargeted inhibitor of Bcr-Abl and Src-family kinases. This study was aims to assess the efficacy and safety of Dasatinib in CML patients who were either newly diagnosed or resistant/intolerant to Imatinib.
Methods: A prospective observational study was conducted at Dhaka Medical College & Hospital from July 2016 to June 2017. A total 31 patients with different phases of CML were included in this study. All patients were treated with Dasatinib 100 mg daily and monitored over 12 months. Molecular responses were assessed through quantitative PCR and hematologic responses were evaluated via complete blood counts.
Results: Among the 31 patients, two died and two discontinued treatment. Of the remaining 27, 23 (85%) achieved complete hematologic response (CHR), 12 (44%) achieved major molecular response (MMR) and 3 (11%) attained complete molecular response (CMR). All four chronic-phase CML (CML-CP) patients who received Dasatinib as frontline therapy achieved molecular response within one month of starting therapy. Responses were lower in more advanced disease stages, with two blast-phase patients dying.
Conclusions: Dasatinib demonstrated significant efficacy and safety in treating CML, particularly in chronic-phase patients and those resistant to Imatinib.
Relationship between stroke and compliance of antihypertensive medication
Authors: Roy Debashis , Shahidulla Muhammad , Morshed Mamun , Roy Chayan , Sabuz Mahmudul Hasan , Chowdhury Supta
Published: January 2025

Background: Stroke is a leading cause of death and long-term disability globally, with hypertension being a key modifiable risk factor. Effective management of hypertension through medication compliance is crucial for reducing the risk of both initial and recurrent strokes. However, non-compliance with antihypertensive medication is a common challenge, particularly in resource-constrained countries like Bangladesh, where awareness and access to healthcare can be limited. This study aimed to investigate the relationship between antihypertensive medication compliance and the incidence of stroke, as well as the risk of stroke recurrence, in hypertensive patients admitted to Dhaka Medical College Hospital.
Methods: A descriptive cross-sectional study was conducted between March and August 2010, involving 100 stroke patients diagnosed clinically and confirmed by CT scan. Data on patients' hypertension status, medication adherence, and stroke history were collected through interviews and medical record reviews. Statistical analysis was conducted using SPSS software (Version 12) to explore the relationship between compliance and stroke occurrence.
Results: From 100 stroke patients, 65% were previously diagnosed with hypertension. Among these patients, 18 (27.7%) were compliant and 47 (72.3%) were non-compliant with their prescribed antihypertensive medication. The recurrence of stroke was significantly higher in non-compliant patients, with 66.67% experiencing a second stroke, compared to 33.33% among compliant patients.
Conclusion: There is a significant association between non-compliance with antihypertensive medication and both the onset and recurrence of stroke. Enhancing patient adherence to antihypertensive therapy through education and healthcare interventions is vital to reducing stroke-related morbidity and mortality.
Postpartum depression associated with sex preference among rural Bangladeshi mothers
Authors: Chowdhury Tanjida , Islam M. Nazrul
Published: January 2025

Background: Maternal depression, particularly postpartum depression (PPD), significantly impacts women’s well-being and can have long-term effects on child health, development, and behavior. The purpose of this study was to evaluate the association between postpartum depression and sex preference among rural Bangladeshi mothers. The aim of the study was to evaluate the association between postpartum depression and sex preference among rural Bangladeshi mothers.
Methods: This cross-sectional study, conducted in Banchanagar village, Laxmipur District, Bangladesh, from January to December 2014, focused on postpartum depression among rural mothers with children aged 0-12 months and its association with sex preference. A total of 219 postpartum women, aged 15-49 years, participated. Data were collected using a pre-tested, semi-structured questionnaire, including the Edinburgh postnatal depression scale (EPDS), with double data entry and analysis in SPSS.
Results: Of the 219 mothers, most had a wanted pregnancy (87.20%), with 60% experiencing complications during pregnancy. Most had no family history of depression, and a majority showed a low probability of depression. Over half considered the sex of the child, with most satisfied with it. Logistic regression showed that the sex of the child, the husband's views, and the mother’s satisfaction were significant factors influencing postpartum depression.
Conclusions: In rural Bangladesh, postpartum depression is notably higher among mothers who give birth to female children, driven by strong cultural preferences for male offspring and negative family reactions toward daughters.
Frequency of autoantibody formation in multi-transfused thalassemia patients at a tertiary care hospital: a cross-sectional study
Authors: Al-Mamun A. B. M. , Islam M. Ashadul , Fatema Kaniz
Published: January 2025

Background: Autoantibodies are produced by the immune system against the body’s own proteins, such as red blood cells, particularly after transfusions. This phenomenon, known as erythrocyte autoimmunization, has been a recognized complication of repeated transfusions. The purpose of this study was to evaluate the frequency of autoantibody formation in multi-transfused thalassemia patients at a tertiary care hospital. The aim of the study was to detect the frequency of autoantibody formation in multi-transfused thalassemia patients at a tertiary care hospital.
Methods: This cross-sectional study at the department of transfusion medicine, BSMMU, Dhaka, conducted from October 2017 to September 2018, included 384 thalassemia patients who received at least 10 units of red cell concentrate. Informed consent was obtained, and data collection involved patient interviews, clinical exams, and hematological tests. Statistical analysis using SPSS version 23.0 included Chi-square, Fisher’s exact, and t-tests, with significance set at p<0.05.
Results: In the study of 384 patients, 43.5% were under 10 years old, with a majority of 52.9% male. Coombs’ test showed 3.1% DCT positive, 7.5% ICT positive, and 4.2% positive for both. All 12 DCT-positive patients had a history of drug use, and 7.7% had undergone splenectomy.
Conclusions: In conclusion, regular blood transfusion in thalassemia patients is a key factor in autoimmunization, with lower antibody formation in females, younger patients, and those with blood group B, while Rh phenotype-matched blood and prestorage leukodepletion may help reduce autoantibody formation.
Factors associated with postnatal care seeking behavior among mothers of infants
Authors: Sarkar Juthi , Yasmin Farida , Biswas Debashis , Uddin M. Imtiaz , Nowshin Sharmina , Ferdous Fahmida , Rahman M. Moklesur , Shafiuzzaman M.
Published: January 2025

Background: Postnatal period is a critical phase in the lives of mothers and newborn babies. Lack of appropriate care during this period could result in significant ill health and even death. Hence the study was carried out to identify the factors associated with postnatal care seeking behavior among mothers of infants.
Methods: This descriptive type of cross-sectional study was conducted at EPI centers of Sadar upazilla of Magura district from January to December 2023 among purposively selected 384 rural women of reproductive age who had at least one living child aged between 6 weeks to 10 months after obtaining ethical clearance from ethical review committee (ERC) of Dhaka Medical College.
Results: The average age of respondents was 24.28±3.52 years, with 84.1% aged 18-27 years. Among mothers, 59.6% completed primary education, while 10.2% reached secondary or higher education levels. Most (91.1%) were housewives, with 57% residing in joint families. While most of participants received ANC, only 35.5% sought PNC. The primary reasons for avoiding PNC included lack of awareness (28.9%) and financial constraints (23.7%). Significant associations were found between PNC utilization and mothers’ education, delivery complications, and decision-making authority within the family (p<0.05).
Conclusions: To improve utilization of postnatal care, national and local level action plan should be introduced to promote postnatal care delivery. PNC awareness campaign, motivation and economic empowerment programs for targeting mothers from the impoverished area need to be implemented.
Postoperative pain management in gynecologic laparoscopic surgeries
Authors: Nurul Amin Mohammad , Bhattacharjee Ramanuj , Ferdouse Lisa Shahreen , Akhter Sunzida
Published: January 2025

Background: Postoperative pain management is crucial in gynecologic laparoscopic surgeries, as inadequate pain relief can delay recovery and affect patient satisfaction. This study evaluated the effectiveness of different postoperative pain management strategies in a cohort of female patients undergoing elective procedures. The primary objective was to assess the effectiveness of multimodal analgesia, including nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, and regional anesthesia, on postoperative pain relief. Secondary objectives included evaluating side effects associated with these pain management strategies.
Methods: This cross-sectional observational study was conducted from July 2022 to June 2024 at the department of anesthesia, in different private clinics in Sylhet region, Bangladesh. A total of 60 adult female patients aged 18 to 65 years undergoing elective gynecologic laparoscopic surgeries were included. Data were collected using patient interviews and medical records, assessing pain levels using the visual analog scale (VAS) at 1, 6, 12, and 24 hours postoperatively. Statistical analysis was performed using SPSS software.
Results: Among the 60 participants, the mean age was 35 years, with 55% undergoing laparoscopic hysterectomy and 45% laparoscopic cystectomy. At 1 hour postoperatively, the mean VAS score was 6.5±1.2, decreasing significantly to 2.2±0.9 by 24 hours (p<0.01). Pain management strategies included NSAIDs in 75% of patients, opioids in 50%, and regional anesthesia in 41.7%. The incidence of adverse effects varied: nausea was reported in 33.3% of opioid users compared to only 6.7% in NSAID users.
Conclusions: The findings indicate that implementing multimodal analgesia, particularly incorporating regional anesthesia, can enhance postoperative pain management in gynecologic laparoscopic surgeries. This approach not only improves pain relief but also minimizes the adverse effects commonly associated with opioid use.
Efficacy of educational campaign on human leucocyte antigens screening for stem cell donation
Authors: Saikia Bharati , Tripathi Shivangi , Lawai Sonia , Sharma Sakshi , Sharma Deeksha , Goyal Tamanna , Rajeswari Saomya
Published: January 2025

Background: Nearly all cells express the proteins known as human leukocyte antigens, or HLA. They aid in distinguishing our own cells from foreign substances and are principally in charge of the body's immunological response. It's interesting to note that every person inherits a distinct collection of antigens from their parents, with half coming from the mother and the other half from the father. This implies that these options can be programmed into youngsters from birth. This study aimed to evaluate how well undergrad students in particular colleges in greater Noida, Uttar Pradesh, are informed about HLA screening for stem cell donation.
Methods: Using convenience sample techniques, a pre-experimental study design is used to evaluate the awareness programme on HLA screening for stem cell donation.
Results: According to the study's findings, the majority of the sample (84%) had poor knowledge of stem cell donation during the pre-test, 16.0% had average knowledge, and 0% had good knowledge. During the post-test, however, the majority (61.0%) had good knowledge, with around 30.0% having average knowledge and only 9.0% having poor knowledge.
Conclusions: In summary, the majority of participants had low pre-test knowledge of HLA and stem cell donation; but, following an awareness presentation on the subject, most of them performed well on the post-test and had good understanding about HLA, DKMS, and stem cell donation. The awareness campaign was a success all around, and some of the participants are even eager to give.
Preoperative and intraoperative factors that influence development of systemic inflammatory response syndrome following percutaneous nephrolithotomy
Authors: Donthiri Sandeep Reddy , Shaik Jamal , Praveen A. P. S. Guru , Ramesh M. Laxmi , Reddy P. Vedamurthy
Published: January 2025

Background: Sepsis is one of the complications of PCNL. Various pre operative and intra operative factors are associated with its development. Sepsis initially starts with SIRS-Systemic Inflammatory Response Syndrome. Early diagnosis and treatment of SIRS also prevents the development of sepsis during the post operative period which markedly reduces the hospital stay and cost of care associated with the treatment and prevents mortality which can be attributed to septic shock. This study aimed to study the incidence of SIRS in the patients who underwent PCNL. Also, to study the pre operative and intra operative factors associated with development of SIRS in patients who underwent PCNL.
Methods: An observational study was conducted in the Department of Urology, Narayana Medical College and Hospitals, Nellore for 18 months from June 2021 to November 2022. A convenient sample of 100 were selected among the patients who underwent percutaneous nephrolithotomy procedure.
Results: 36% developed SIRS during the course of treatment. The association between development of SIRS and pelvic urine culture and sensitivity (P=0.018), stone culture and sensitivity (P=0.0004), requirement of blood transfusion (P=0.03) and operating time (P=0.0001) was statistically significant.
Conclusions: The patients with risk factors like positive pelvic urine culture and sensitivity, positive stone culture and sensitivity, requirement of blood transfusion and longer duration of surgery are to be carefully monitored and treated to prevent the development of SIRS.
Comparative study of vicryl polyglactin (910) versus chromic catgut for episiotomy repair
Authors: Kaur Nazamdeep , Kaur Amrit P. , Manku Harpoonam , Kaur Kiranjeet
Published: January 2025

Background: The aim of the study was to compare two different absorbable suture materials, namely vicryl rapide (no. 2-0) and chromic catgut (no.1-0) for episiotomy repair and evaluate their outcomes related to short term maternal post-partum morbidity.
Methods: The prospective randomized comparative study was conducted in the department of obstetrics and gynecology, Bebe Nanki Mother and Child Care Centre, Amritsar, for a period of 1 year, with 200 pregnant females admitted in the labour room who needed episiotomies for vaginal delivery and were randomly allocated for episiotomy repair with either vicryl polyglactin (910) (no. 2-0) or chromic catgut (no.1-0) with 100 patients in each group and various parameters like pain, swelling, tenderness, dyspareunia, wound discharge and dehiscence were assessed in each group at 24-48 hours, 10-14 days and 6 weeks postpartum.
Results: The sociodemographic characteristics were comparable in both groups. Compared to chromic catgut, the vicryl rapide group was associated with lesser pain (7% versus 21%), feeling of stitches (20% versus 38%) and swelling and tenderness (4% versus 12%). There was significantly less wound disruption (3% versus 12%), feeling of stitches (11% versus 21%) and wound discharge (1% versus 7%) in vicryl rapide group at 10-15 days. Residual pain and dyspareunia were also less in vicryl group at 6 weeks.
Conclusions: It can be concluded that vicryl rapide is a superior suture material than chromic catgut for repair of episiotomy as it results in lesser complications and improved wound healing.