bluuebunny/crossref_metadata_2025 huggingface dataset:
Outbreaks of Foot-and-Mouth Disease in Burundi, East Africa, in 2016, Caused by Different Serotypes
Authors: Estevez Garcia Andrea Isabel , Lefebvre David J. , Nyabongo Lionel , Haegeman Andy , Nkundwanayo Canesius , De Vleeschauwer Annebel , Ntakirutimana Désiré , De Leeuw Ilse , Nsanganiyumwami Deogratias , Niyokwizera Pascal , van den Berg Thierry , Niyokwishimira Alfred , Clercq Kris De
Published: May 2022

Burundi is a small, densely populated country in the African Great Lakes region. In March 2016, several hundreds of cattle were reported with vesicular lesions, suggesting foot-and-mouth disease (FMD). Epithelial samples, saliva, and blood were collected in six of the affected provinces spread over the country. The overall seroprevalence of FMD virus (FMDV) in the affected herds, as determined by antibodies against FMDV non-structural proteins, was estimated at 87%. Antibodies against FMDV serotypes O (52%), A (44%), C (19%), SAT1 (36%), SAT2 (58%), and SAT3 (23%) were detected across the provinces. FMDV genome was detected in samples from five of the six provinces using rRT-PCR. FMDV was isolated from samples from three provinces: in Cibitoke province, serotypes A and SAT2 were isolated, while in Mwaro and Rutana provinces, only serotype SAT2 was isolated. In Bururi and Cankuzo provinces, the serological profile suggested a recent incursion with serotype SAT2, while in Bubanza province, the serological profile suggested past incursions with serotype O and possibly serotype SAT1. The phylogenetic assessments showed the presence of topotypes A/Africa/G-I and SAT2/IV, similarly to previously characterized virus strains from other countries in the region, suggesting a transboundary origin and necessitating a regional approach for vaccination and control of FMD.
In Vitro and In Vivo Assessments of Two Newly Isolated Bacteriophages against an ST13 Urinary Tract Infection Klebsiella pneumoniae
Authors: Laforêt Fanny , Antoine Céline , Blasdel Reuter Bob , Detilleux Johann , Pirnay Jean-Paul , Brisse Sylvain , Fall Abdoulaye , Duprez Jean-Noël , Delcenserie Véronique , Thiry Damien
Published: May 2022

Antibiotic resistance represents a major public health concern requiring new alternatives including phage therapy. Klebsiella pneumoniae belongs to the ESKAPE bacteria and can cause urinary tract infections (UTIs). The aims of this study were to isolate and characterize new bacteriophages against a K. pneumoniae strain isolated from UTIs and to assess their efficacy in vitro and in vivo in a Galleria (G.) mellonella larvae model. For this purpose, two bacteriophages were newly isolated against an ST13 K. pneumoniae strain isolated from a UTI and identified as K3 capsular types by wzi gene PCR. Genomic analysis showed that these bacteriophages, named vB_KpnP_K3-ULINTkp1 and vB_KpnP_K3-ULINTkp2, belong to the Drulisvirus genus. Bacteriophage vB_KpnP_K3-ULINTkp1 had the narrowest host spectrum (targeting only K3), while vB_KpnP_K3-ULINTkp2 also infected other Klebsiella types. Short adsorption times and latent periods were observed for both bacteriophages. In vivo experiments showed their ability to replicate in G. mellonella larvae and to decrease host bacterial titers. Moreover, both bacteriophages improved the survival of the infected larvae. In conclusion, these two bacteriophages had different in vitro properties and showed in vivo efficacy in a G. mellonella model with a better efficiency for vB_KpnP_K3-ULINTkp2.
Immunogenicity of the 13-Valent Pneumococcal Conjugate Vaccine (PCV13) Followed by the 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23) in Adults with and without Immunosuppressive Therapy
Authors: Garcia Garrido Hannah M. , Vollaard Albert , D’Haens Geert R. , Spuls Phyllis I. , Bemelman Frederike J. , Tanck Michael W. , de Bree Godelieve J. , Meek Bob , Grobusch Martin P. , Goorhuis Abraham
Published: May 2022

Immunosuppressive therapy increases the risk of pneumococcal disease. This risk can be mitigated by pneumococcal vaccination. The objective of this study was to investigate the immunogenicity of the 13-valent pneumococcal conjugate vaccine (PCV13), followed by the 23-valent pneumococcal polysaccharide vaccine (PPSV23), in adults with and without immunosuppressive therapy. We performed a prospective cohort study among adults using conventional immunomodulators (cIM), biological immunomodulators (bIM), combination therapy, and controls during 12 months. The primary outcome was seroprotection, defined as the proportion of patients with a postimmunization IgG concentration of ≥1.3 µg/mL for at least 70% (17/24) of the serotypes of PCV13 + PPSV23. We included 214 participants. For all 24 vaccine serotypes, IgG levels increased significantly in both treatment subgroups and controls, with peak seroprotection rates of 44% (combination therapy), 58% (cIM), 57% (bIM), and 82% (controls). By month 12, seroprotection had decreased to 24%, 48%, 39%, and 63%, respectively. Although pneumococcal vaccination with PCV13 + PPSV23 was immunogenic in all treatment groups, impaired vaccination responses were observed in patients using immunosuppressive medication. Apart from the obvious recommendation to administer vaccines before such medication is started, alternative vaccination strategies, such as additional PCV13 doses or higher-valent pneumococcal vaccines, should be investigated.
Quantitative and Qualitative Difference in Antibody Response against Omicron and Ancestral SARS-CoV-2 after Third and Fourth Vaccination
Authors: Hein Sascha , Mhedhbi Ines , Zahn Tobias , Sabino Catarina , Benz Nuka Ivalu , Husria Younes , Renelt Patricia Maria , Braun Floriane , Oberle Doris , Maier Thorsten J. , Hildt Christoph , Hildt Eberhard
Published: May 2022

Waning immunity against SARS-CoV-2 and the emergence of variants, especially of the most distant variant, Omicron, affect titers of neutralizing antibodies in the sera of vaccinated individuals. Thus, two vaccinations with the mRNA vaccine BNT162b fail to induce neutralizing antibodies against the Omicron variant. A first booster vaccination increases Omicron-RBD-binding IgG and IgA and neutralizing capacity. In comparison, the Wuhan isolate titers of the Omicron variant binding antibodies are 8.5 lower. After a third vaccination, induction of Omicron-RBD- and Wuhan-RBD-binding antibodies follows the same kinetic. Five to six months after the third vaccination, there are still Omicron-RBD-binding antibodies detectable, but 35.9 percent of the analyzed sera fail to neutralize the Omicron variant, while all sera efficiently neutralize the Delta isolate. In the case of the Wuhan-RBD, a significantly larger number of stable antigen–antibody complexes is formed than in Omicron-RBD. A fourth vaccination with mRNA-1273 temporarily restores levels of Omicron-, Delta- and Wuhan-specific antibodies. Comparing different booster strategies revealed that the breadth of the immune response is not affected by the vaccination regimen. Taken together, these data indicate that booster vaccinations (third and fourth dose) increase the breadth of the immune response, but there is a qualitative difference of antibodies with respect to the stability of antigen–antibody complexes and persistence of antibody titers.
Perancangan Prototype Sistem Informasi Akuntansi (SIA) pada PT XYZ
Authors: Martono
Published: May 2022

PT XYZ is a company that has many business fields such as retail up to financing. PT XYZ at this time, running its business PT XYZ also utilizes information technology in the form of a general computer-based information system, the result of this current system having weaknesses in terms of data security to the high potential for human error. This happened because system users must reprocess all the data using a separate system and open other files before finally being able to process a financial report. Due to this problem, the author finally conducted a study entitled the design of a prototype accounting information system (AIS) at PT XYZ. The accounting information system (AIS) which is the final result of this research will be explained using use case diagrams and class diagrams modeling. The final result of this research will be in the form of prototypes of an accounting information system (AIS) which describes the user's flexibility in managing data categories, users, income transactions, expenditure transactions, debts, receivables, reports related to financial transactions at PT. XYZ and view of the transaction recaps.
Implementasi Metode Algoritma Genetika Untuk Penjadwalan Matakuliah Pada Universitas Dinamika Bangsa
Authors: Agus
Published: May 2022

Perkembangan teknologi yang begitu pesat sangat berdampak pada munculnya metode baru dalam algortima pemrograman, salah satunya adalah metode algortima genetika. Algoritma genetika sendiri merupakan metode yang dapat mengoptimalkan sebuah nilai melalui proses pencarian. Nilai yang optimal didapat dari generasi populasi, yang mana tiap populasi akan dilalukan seleksi serta dilakukan cross over terhadap populasi terbaik, sehingga muncul evolusi dari populasi yang baru berdasarkan besarnya nilai dari laju mutasi. Metode algoritma genetika dapat dimanfaatkan untuk mengoptimalkan proses penjadwalan mata kuliah pada Universitas Dinamika Bangsa, sehingga proses kerja manusia dapat dibantu untuk berkerja lebih cepat.
Sistem Informasi Penjualan Online Berbasis Mobile Pada Supermarket Kasimura
Authors: Muhamad
Published: May 2022

Supermarket Kasimura merupakan salah satu bidang usaha yang bergerak pada bidang penjualan produk kebutuhan hidup manusia. Dalam melakukan proses penjualan produk. Supermarket masih menggunakan cara manual. Pelanggan harus datang ke Supermarket Kasimura untuk melakukan proses pembelian. Cara seperti ini masih dianggap kurang efektif dan efisien terutama dari ruang lingkup pemasaran dan promosi produk Supermarket Kasimura. Proses pemasaran dan promosi hanya terbatas pada ruang lingkup sekitar Supermarket Kasimura. Penulis melakukan penelitian dengan tujuan untuk membangun sebuah sistem informasi berbasis mobile android yang dapat memudahkan pelanggan dalam proses melakukan pemesanan dan penjualan produk yang tersedia pada Supermarket Kasimura. Metode pengembangan sistem yang digunakan adalah metode waterfall. Tool yang digunakan untuk membuat rancangan secara visual menggunakan Unified Modeling Language (UML). Sistem informasi dibangun dengan menggunakan Kodular dan database Airtable. Dengan adanya sistem informasi ini, diharapkan dapat memudahkan pelanggan dalam memperoleh informasi mengenai produk yang tersedia dan melakukan pemesanan produk pada Supermarket Kasimura. Selain itu, dapat membantu pihak Supermarket Kasimura dalam melakukan penjualan produk dan memperluas ruang lingkup pemasaran melalui mobile android secara online.
EVOLUTION OF CREATIVE ACCOUNTING AND WAYS TO IMPROVE IT
Authors:   Chernivtsi Institute of Trade and Economics of KNUTE, Bagrii Konon
Published: May 2022

In the modern activity of enterprises and organizations, which is developing dynamically, the number of accounting tasks is constantly growing. This is due to the improvement of accounting for the introduction of new rules for the recognition, evaluation and reflection of facts and phenomena of economic life. Such changes require a great deal of knowledge from the accountant not only on the legal regulation of accounting but also the correct professional judgment. A new system of financial reporting regulation has created the preconditions for the emergence of a new area of accounting, namely creative accounting. On the one hand, any accounting method that does not meet generally accepted practices or standards can be considered creative. At its worst, it is the process of selecting the company’s accounts in such a way that they present its activities in a more favourable light. The application of creative accounting methods is of great importance under operation of enterprises according to International Financial Reporting Standards. The relevance of the study of creative accounting is growing, as it is based on the provision of a set of legal methods aimed at providing property and financial state of the firm in the desired or appropriate form, when often one expression can be used in completely opposite senses. The article considers the reasons for the emergence of creative accounting, as well as the stages of its evolution. The urgency and importance of this problem is shown, both for the compilers of financial statements and for external users of such information. The author’s interpreting the concept of "creative accounting" is also proposed. The necessity of conducting research in the direction of finding ways to improve creative accounting is substantiated. The existing approaches of researchers to eliminate the negative consequences of creative accounting are analyzed. Two main groups of research approaches to improving creative accounting have been identified and analyzed. The necessity of improving the procedural aspects of creative accounting based on the application of the concept of true and fair representation is substantiated. The main concept provisions of true and fair reflection, the use of which provides an adequate picture of the economic reality of the enterprise in the financial statements are considered. A "pendulum" of attitude to creative accounting in the scientific and professional community has been built. The author reveals the causal relationship between the categories of truth and justice in the context of the concept of True and Fair View.
Vision systems as a type of information and telecommunications in matters of environmental monitoring water environment
Authors:   Admiral Makarov State University of Maritime and Inland Shipping, Martynov V.L.
Published: May 2022

To obtain high-quality video images characterizing the ecological condition of the underwater marine environment in real time, it is necessary to create modern automated systems for accumulating and processing video information, which are aggregated from autonomous underwater devices equipped with special technical means of control, in particular, television cameras. Technologies for environmental monitoring using these systems make it possible to study the seabed for the presence of unfavorable environmental factors and foreign objects, to identify them, as well as to map the seabed topography in order to provide the coordination center with a full volume of data on the bottom ecological situation. All this requires high-resolution video transmission from autonomous underwater devices. The traditional hydroacoustic underwater systems for accumulating and processing video information are being replaced by open systems for its optical transmission and reception, based on laser technologies. An obstacle for the wider use of hydroacoustic fields is the low speed of video information transmission to surface objects. The article substantiates the expediency of using open optical communication systems to create high-speed underwater information telecommunications, among which the most preferable are laser systems that have sufficient broadband, which is necessary to ensure a high video stream speed.
Intelligent transport and technological means of a new generation and the underlying the concept of «digital autolift»
Authors:   St. Petersburg Federal Research Center of the Russian Academy of Sciences, Stepanov P.V.
Published: May 2022

The article describes the concept of a «Digital Autolift», which is the basis of an intelligent transport and technological means (ITTS) designed for aircraft maintenance at the airport. The changes in the architecture and functionality of the autolift are analyzed with the introduction of digital technologies and the appearance of an on-board computer as the main tool for monitoring and managing ITTS systems. It describes what new transport and technological means may appear and how existing ones are transformed after digitalization. Collision prevention systems, control of technological operations, external communications system and proactive control and management system of ITTS are described.
Analysis of insider threat detection methods tested on CERT dataset
Authors:   St. Petersburg Federal Research Center of the Russian Academy of Sciences, Bystrov I.S. , Kotenko I.V.
Published: May 2022

Applying artificial intelligence for insider threat detection faced a number of challenges: lack of data, user behavior modeling, etc. Meanwhile, there are open datasets for research and there are effective approaches of insider threat detection. This work considers studies that utilizes one of the popular datasets — CERT. A comparative analysis contains features used for user behavior modeling and insider threat detection methods.
Search for statistically significant clusters in networks and biomedical applications
Authors:   PRNRMU, Pyatnitskiy A.M. , Gukasov V.M. ,   Republican Research Scientific-Consulting Center Expertise
Published: May 2022

A new, statistically based method of clustering previously used by authors for analysis of frequency and point data in epidemiology and for searching clusters in samples is applied to discovering clusters in graphs or networks. Graph clustering or community detection is often used in biomedical applications. Nevertheless methods existing in literature have no sufficient statistical background and the question of significance for revealed clusters usually is not considered. In the case when clusters do not form the whole network false positive results are inevitable. We propose method for discovering statistically significant clusters. It is compared with nine methods existing in literature. It is shown that only proposed method can discover significant clusters successfully discriminating them from phone consisting from randomly connected network objects.
An up-to-date digital intellectual resource for ensuring biological safety in healthcare
Authors:   Maikop State Technological University, Agirov A.H. , Gukasov V.M. , Zakharov V.A. , Konyshev I.S. , Orlov D.A. , Tarasov B.V. ,   Research Institute of Communications and Control Systems,   ZAO NPTs «Modul»
Published: May 2022

The main results on the creation of the System of intellectual support for management decisions to counter biological threats, including those of a terrorist nature, implemented in the Republic of Adygea, are presented. These results, according to the authors, can form the basis of the National System of Protection against New Infections (Decree of the President of the Russian Federation of October 12, 2020, No. 620).
Correction of physical development of women in the conditions of aerobic fitness
Authors:   State Research Institute chemistry and technology of organoelement compounds, Golovanov S.A.
Published: May 2022

At studying an opportunity of use and development of techniques of application of a preparation Trekrezan for restoration of a condition of an organism at women in the shortest terms, it is established, that at application of biologically active additive Trekrezan in a doze 0,5х2 once a day during 21 day two times a year leads to the highest parameters of motivation to employment, significant decrease in time of restoration after loading and to increase of parameters of physical development.
ANALYSIS OF THE DEVELOPMENT OF THE INDUSTRIAL COMPLEX OF THE CHECHEN REPUBLIC: SEARCH FOR POSSIBLE “POINTS OF GROWTH”
Authors: Ахмадов М-Э. И. , Хлебников К. В. , Якубов Т. В.
Published: May 2022

В большинстве случаев промышленный комплекс является основой экономики регионов, поскольку обеспечивает основной вклад в формирование ВРП. На сегодняшний день доля промышленного комплекса региона в ВРП составляет не более 6%. В Чеченской Республике 2022 год объявлен годом промышленности, что подчеркивает масштаб усилий региональных органов власти, направленных на качественный рост данного сектора экономики. В статье анализируются динамика основных показателей промышленного комплекса республики, а также рассматривается деятельность основных составляющих элементов: добывающего сектора и обрабатывающих производств. Что, в свою очередь, позволило выделить те специализированные производства, которые могли бы стать «точками роста» экономики региона.

In most cases, the industrial complex is the basis of the regional economy, since it provides the main contribution to the formation of GRP. Unfortunately, this cannot be said about the industrial complex of the Chechen Republic, whose contribution to the GRP is no more than 6%. In the Czech Republic, 2022 has been declared the year of industry, which underlines the scale of the efforts of regional authorities aimed at the qualitative growth of this sector of the economy.The article analyzes the dynamics of the main indicators of the industrial complex of the Czech Republic, and also examines the activities of the main constituent elements: the extractive sector and manufacturing industries. Which, in turn, made it possible to single out those specialized industries that could become “growth points” for the region’s economy.
Evaluation of the border traps in LPCVD Si3N4/GaN/AlGaN/GaN MIS structure with long time constant using quasi-static capacitance voltage method
Authors: Sun Haozhe , Lin Wei , Yin Ruiyuan , Chen Jianguo , Hao Yilong , Shen Bo , Wang Maojun , Jin Yufeng
Published: May 2022

We extract the electric properties of border traps with long time constant in low-pressure chemical vapor deposition (LPCVD) Si3N4/GaN/AlGaN/GaN metal–insulator–semiconductor (MIS) structure using quasi-static capacitance voltage method. The energy and depth distribution of the border traps is calculated based on the analysis of energy band diagram and charging dynamic of border traps in the MIS structures. With this method, it is found that LPCVD Si3N4/GaN/AlGaN/GaN MIS structure have a high density of border traps in the order up to 1021 cm−3 eV−1 located at energy level between E
C,GaN − 0.04 eV and E
C,GaN − 0.66 eV with distance of 1.0–4.2 nm from the Si3N4/GaN interface. Microstructure analysis suggests that the high density of border traps is possibly correlated to the oxygen content at the Si3N4/GaN interface. Meanwhile, the proposed method is also suitable for MIS or metal-oxide-semiconductor structure on other semiconductors, providing another powerful tool to analysis the physical properties of border traps.
How will Local Energy Markets influence the pan-European Day-ahead Market and Transmission Systems? A Case Study for Local Markets in France and Germany
Authors: Schmitt Carlo , Schumann Klemens , Kollenda Katharina , Blank Andreas , Rebenaque Olivier , Dronne Théo , Martin Arnault , Vassilopoulos Philippe , Roques Fabien , Moser Albert
Published: May 2022

The energy system decarbonization leads to a decentralization of generation and flexibility. Among the new concepts to integrate the distributed flexibility are local energy markets. While a broad range of research investigates local energy markets on a distribution grid level in detail, research on their system impact has been limited. Therefore, we develop a framework to investigate different configurations of local markets and operation of distributed energy resources and their interaction with the wholesale markets. This framework is applied to a pan-European case study with detailed bottom-up modeling of local energy markets in France and Germany. Additionally, transmission grid simulations are carried out to investigate the impact of local trading on grid congestions. Our results show that a direct coordination of distributed flexibility within the wholesale market is more efficient than a preference of local trading. Nonetheless, local energy markets can be used as an incentive for expansion of distributed flexibility as well as a way to break down the complexity of coordinating millions of distributed assets in a single market. Additionally, our results show that local trading relieves the transmission grid. 
Satisfacción académica de los estudiantes de un Instituto Público de la Provincia de Tungurahua
Authors: Valdiviezo Rodríguez Diana Carolina , Ulloa Juan Carlos , Sánchez Andrea , Cando Sandra
Published: May 2022

OBJETIVO: caracterizar la satisfacción académica de los estudiantes del Instituto Público de la Provincia de Tungurahua. MÉTODO: se parte de una investigación no experimental, de enfoque cuantitativo, alcance descriptivo y corte transversal. Para el diagnóstico se aplica a un total de 405 estudiantes de dicha institución el cuestionario Satisfacción de los Estudiantes Universitarios con su Educación (SEUE). RESULTADOS: oscilan entre bastante satisfecho y poco satisfecho en las diferentes dimensiones, siendo que lo peor valorado son los servicios de la institución. Además, se encuentra que las mujeres muestran menos satisfacción en las condiciones básicas de la infraestructura, los servicios de la institución y condiciones de seguridad, siendo esas diferencias estadísticamente significativas. Por otra parte, en cuanto a las carreras, la carrera de contabilidad tiene puntajes significativamente superiores en la satisfacción en comparación con la carrera de Software y Diseño. CONCLUSIÓN: el artículo hace referencia al nivel de satisfacción de los estudiantes del Instituto Público de la Provincia de Tungurahua, este oscila entre Poco Satisfecho, y Bastante Satisfecho. Se encontró la necesidad de mejorar los servicios de la institución y de las condiciones de seguridad.
Chemotherapy Compliance and Tolerance in Elderly and Non-Elderly Patients with Colorectal Cancer: A Single Institution Study
Authors: Salleh Norly , Yusof Amirah , Hamdan Mohd Aizat , Sadarman Robi’ah Al-Adawiyah , Noor Shamsiah Mohd
Published: May 2022

The objectives of this retrospective, observational study are to compare the compliance and tolerance rate between elderly and non-elderly patients with colorectal cancer, and to ascertain the stage at presentation. All adult patients with diagnosis colorectal cancer who received first line chemotherapy (adjuvant or palliative) between January 2017-January 2019 were included. Data on demographic, clinic-pathological, treatment and patient outcome were collected. Toxicity data was collected as they appear. These data were then analyzed using IBM®SPSS® Statistics Version 24. Sixty-four patients were included. There were almost equal numbers of elderly and non-elderly patients. Thirty-five patients were Malay (54.7%), Chinese 26 (40.6%) and Indian 3 (4.7%). Their age ranges from 38-82 years old. Most patients received FOLFOX regimen (73.4%), followed by Mayo regimen and capecitabine (10.9% each). There was no significance difference in the type of chemotherapy and number of cycles given. The majority received combination therapy rather than single therapy. There was no difference in the terms of toxicity between the study populations. Thirty-three percent of elderly and thirty-five percent of non-elderly patients had no documented chemo-toxicity. The most common toxicity is neutropenia, followed by thrombocytopenia and anaemia. In total, 25% (16 patients) did not complete their chemotherapy for various reasons. Nine were elderly patients (56.3%). Presentation at Stage 3 and 4 accounted for 70.3% (45 patients) of the study population. Elderly colorectal cancer patients’ should be treated with equal therapeutic opportunities as their younger counterparts. Biological age should be considered when deciding treatment regime rather than chronological age.
Research on Humanistic Education for Medical Students in Post-epidemic Era
Authors: Ma Jing
Published: May 2022

The COVID-19 pandemic, which started in early 2020, has not stopped. The need of safety makes people hold on to medicine. People urgently need doctors with noble medical ethics and superb medical skills. The epidemic has brought about changes, but the essence of medical education has not changed. Medical students should not only have medical knowledge and excellent technical level, but also have extensive humanistic feelings and caring ability. Medical education is rooted in humanity. It is of great importance how to improve medical students’ humanistic education in further higher education reform.
Trespassory Art
Authors: Bezanson Randall , Finkelman Andrew
Published: May 2022

The history of art is replete with examples of artists who have broken from existing conventions and genres, redefining the meaning of art and its function in society. Our interest is in emerging forms of art that trespass-occupy space, place, and time as part of their aesthetic identity. These new forms of art, which we call trespassory art, are creatures of a movement that seeks to appropriate cultural norms and cultural signals, reinterpreting them to create new meaning. Marcel DuChamp produced such a result when, in the early twentieth century, he took a urinal, signed it, titled it Fountain, and called it art.

Whether they employ twenty-first-century technologies, such as lasers, or painting, sculpture and mosaic, music, theatre, or merely the human body, these new artists share one thing in common. Integral to their art is the physical invasion of space, the trespass, often challenging our conventional ideas of location, time, ownership, and artistic expression. Their art requires not only borrowing the intellectual assets of others, but their physical assets. This is trespassory art-art that redefines and reinterprets space-art that gives new meaning to a park bench, to a billboard, to a wall, to space itself.

Our purpose is to propose a modified regime in the law of trespass to make room for the many new forms of art with which we are concerned-art that is locationally dependent or site specific. We begin by briefly describing and characterizing these often-new artistic forms. This provides a jumping off point for addressing the basic question this Article seeks to address-should the law accommodate these new types of art, and if so, to what degree? We first turn to the law of trespass, with particular focus on real property, both public and private, but also with an eye to personal and intellectual property. We conclude that adjusting trespass remedies for artistic trespass through a set of common law privileges would better balance the competing interests of owners and artists than do current trespass rules. We then turn to a set of constitutional issues and conclude that our common law proposal is consistent with, and in some ways perhaps required by, the First Amendment. Finally, we summarize our proposal and then revisit the value of trespassory art as art in our creative culture.
ПРОБЛЕМА НРАВСТВЕННОГО СОВЕРШЕНСТВОВАНИЯ ЧЕЛОВЕКА В ПОЗДНИХ ПРОИЗВЕДЕНИЯХ Л.Н. ТОЛСТОГО
Authors: Лабазанова М.В. , Садулаева М.Х.
Published: May 2022

Статья посвящена лучшим произведениям великого русского писателя, в которых он доказывает способность человека становиться лучше, бороться за свою духовность и божественное начало. Конечно, эти нравственно-этические искания Толстого следует связывать с его собственным духовным кризисом и его преодолением благодаря обращению к высшим и настоящим (это особенно подчеркивал автор) религиозным ценностям. В повести «Смерть Ивана Ильича» героя мучает мысль о бесцельно, бездарно прожитой жизни, и лишь в состоянии агонии, почувствовав любовь, которой его наполняет сын, он испытал минуты нравственного просветления. В следующем анализируемом произведении «Отец Сергий» автор делает акцент на мысли, что помощь людям должна быть бескорыстной, служение должно свершаться для Бога, а не для людей, несущих благодарение и восхваление. В «Хозяине и работнике» мы наблюдаем, как через добро к ближнему и веру в Бога даже самый нравственно падший человек может переродиться. В романе «Воскресение» Толстой ставит героев в такую ситуацию, когда проявляются лучшие их качества, о которых их обладатели, возможно, и не догадывались.
КРУЖОК КАК ФОРМА ФОРМИРОВАНИЯ ПОЗНАВАТЕЛЬНОЙ МОТИВАЦИИ МЛАДШИХ ШКОЛЬНИКОВ ВО ВНЕУРОЧНОЙ ДЕЯТЕЛЬНОСТИ
Authors: Айдамирова Х.У. , Булуева Ш.И.
Published: May 2022

В статье рассмотрена внеурочная форма деятельности – кружок как способ формирования познавательной мотивации младших школьников во внеурочной деятельности. Познавательная мотивация важна не только для достижения образовательных результатов в школе, но и для самореализации обучающихся. Ученик с низкой познавательной мотивацией, как правило, отрицательно относится к школе, к учению, проявляет пассивность и равнодушие к урокам и занятиям и, как следствие, рискует оказаться в числе слабоуспевающих. Рассмотрены различные теории, где изучалась познавательная мотивация младших школьников, благодаря чему были разработаны концептуальные основы онтогенеза мотивационной сферы в дошкольном и школьном возрастах. Познавательная мотивация младших школьников зависит от социально-экономических, социокультурных условий жизни, поэтому изучение мотивационной сферы младших школьников не теряет своей актуальности – изменение внешних условий отражается на иерархии мотивов обучающихся. Педагогам необходимо проводить работу по формированию познавательной мотивации, используя все имеющиеся для этого ресурсы школы. Во внеурочных формах школьники могут проявить свои аналитические способности, показать кругозор, эрудицию, что способствует повышению их познавательного интереса. Внеурочная деятельность, реализуемая в формах, отличных от урочной (творческие студии, кружки, спортивные секции и клубы, экскурсии, соревнования, олимпиады, научные исследования, интеллектуальные клубы, общественно полезная деятельность и др.), содержит большой потенциал для развития познавательной мотивации младших школьников при наличии определенных педагогических условий в образовательной организации.
СУЩНОСТЬ И СТРУКТУРА ПОНЯТИЯ «ИННОВАЦИОННЫЕ ТЕХНОЛОГИИ» В КОНТЕКСТЕ ОБРАЗОВАНИЯ
Authors: Каимова П.И. , Бехоева А.А.
Published: May 2022

В статье осуществлена сущностная и структурная характеристика понятия «инновационные технологии» в контексте образования. Сделан вывод о том, что инновация является междисциплинарным термином, который в контексте категориального аппарата педагогики и психологии очень серьезно рассматривается учеными. В отечественной научной мысли существуют различные трактовки сущности и структуры педагогической инновации, а также классификаций и требований к инновационным технологиям и программам. Различают такие инновации, как технико-технологические, социально-экономические, организационно-управленческие. В социальной практике выделяют различные подвиды инноваций, одним из которых являются педагогические инновации. Под педагогической инновацией понимается такое новшество и нововведение в педагогическую практику, которое улучшает педагогическую систему и функционирование данной педагогической системы в целом и ее элементов, а также благотворительно сказывается на всех структурных компонентах педагогического процесса. Также рассмотрено понятие «инновационная программа». Под инновационной программой понимается система инновационных проектов, которые планируется осуществить в ходе единого тематического направления. Важным аспектом инновационной образовательной программы являются её следующие черты: прогностический характер; инновационность содержания программы; инновационный характер применяемых технологий; особенность инноваций в организации процесса обучения; а также инновационный аспект в плане управления образовательной программой.
Birincil yaklaşımlar ve çocuk hakları çerçevesinden çocuklarda madde bağımlılığı
Authors: YİĞİTBAŞ Çağla
Published: May 2022

Madde bağımlılığı, küresel bir halk sağlığı sorunudur. Sonuçları itibarıyla yalnızca bireyi değil, aileyi ve hatta toplumu da etkilemektedir. Ve günümüzde bağımlılığın pek çok türü ile karşılaşılmaktadır. Bağımlılık hemen hemen yaştan kişide görülmekle birlikte sonuçları açısından çocuklardaki bağımlılıklar daha tehlikelidir. Madde bağımlısı çocukların ötekileştirilmesi mevcut sorunun daha da derinleşmesine yol açmaktadır. Konuya çocuk hakları penceresinden bakıldığında; Türkiye’nin de kabul ettiği çocuk hakları sözleşmesinde çocuğun madde bağımlılığından korunması ilkesi bulunmaktadır. Bu bağlamda sözleşmede yer alan “yaşama ve gelişme hakkı” ile “sağlık hizmetlerine erişim hakkı” ve “insana yakışır bir yaşam standardına erişim hakkı” maddeleri de çocukları madde bağımlılığından koruma ya da rehabilite etme anlamında sahip oldukları haklarıdır. Çocukluk döneminde bağımlılığın belirtilerinin anlaşılması koruyucu ve rehabilite edici yaklaşımlar açısından çok önemlidir. Çocuğun yaşı, cinsiyeti, içinde yaşadığı çevre risk nedenleri arasında gösterilmektedir. Literatürde ergenlik dönemi bağımlılık açsından tehlikeli bir dönem olarak kabul edilmektedir. Bu sorunun çözümünde; nedenlerin bilinmesi, etkilerin değerlendirilmesi, çözüm önerileri konusunda bilincin oluşması önemlidir. Son zamanlarda Türkiye’de de çocuklarda madde bağımlılığı oranının artmaya başladığı bildirilmektedir. Bu bağlamda Türkiye, 2023 yılına kadar sürdüreceği bir projeyi başlatmıştır. Projenin hedeflerinin içinde çocuklara yönelik tedbirlerde bulunmaktadır. Türkiye’deki çocukların sıklıkla esrar kullandığı belirlenmiştir. Esrar halisinojen grubunda olan ve merkezi sinir sistemine etki yapan bir maddedir. Çocukların madde bağımlılığından korunması birey, aile ve toplumun çabalarıyla mümkündür. Bu derleme madde bağımlılığını son güncel veriler altında ele almaktadır. Madde bağımlılığının tanılanmasını, nedenlerini, etkilerini, sonuçlarını ve Türkiye’deki yasal düzenlemeleri koruyucu önleyici yaklaşımlar ve çocuk hakları penceresinden incelemektedir.
MATHEMATICAL MODEL OF FINANCIAL INVESTMENT RISK
Authors:   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Vorokova Nodira Kh. , Sennikova Alina E. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Abrosimov Vladimir V. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Vasilchenko Valeria E. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia, Priymak Pavel N. ,   Kuban State Agrarian University named after I. T. Trubilin, Krasnodar, Russia
Published: May 2022

This article measures the amount of income and the degree of risk of financial investments. Analysis of the relationship between income and risks in financial investments is based on the theory of multipurpose linear programming. In the process of using study data obtained using MATLAB software. This approach requires an analysis of the investor's profitability assessment at a constant level of risk and minimized risk with the search for a profitable one. The results of the study are the basis for the formation of a diverse portfolio in the presence of various risks in financial investment. The monitor calculations presented in the article are generated by the application model to define a generic portfolio.
DIGITAL ECONOMY AS A TOOL OF MODERN IT SOLUTIONS IN ECONOMICS AND BUSINESS
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russia, Bekbuzarova Milana I.
Published: May 2022

The integration of the modern economy into the global system of trade and economic relations requires the introduction of the latest technological developments in industrial production. It is the introduction of IT solutions into the economy and business that makes it possible to compete in the global market. The development of the IT industry on a national scale is a criterion for the competitiveness of goods and the country as a whole. Moreover, economic growth without the introduction of information technology becomes almost impossible. The Russian society and the country's leadership rely on the introduction of IT technologies into business and the development of IT solutions by the scientific community. Such a tandem should, according to the country's leadership, become the key to the successful implementation of IT solutions in the economy.
Treatment of Vaccine Induced Myocarditis and Pericarditis Symptoms in Covid-19 Negative Patients: Case Report
Authors: Reinfeld Howard B
Published: May 2022

Myocarditis and Pericarditis have long been considered as possible effects of Covid-19, with retrospective studies demonstrating an increased likelihood of developing new onset cardiac inflammation in the months following a Covid-19 infection. Interestingly, a similar occurrence has been observed with mRNA Covid-19 vaccines, which raises the question whether Covid-19 vaccines increase an existing risk of myocarditis within infected patients or is this development independent of Covid-19 infection. In this report, to explore the possibility, two cases of Covid-19 negative patients shall be discussed who developed symptoms of myocarditis/pericarditis after receiving their vaccine dose.
Stacking Stories
Authors: Merchant Guy
Published: May 2022

What happens when a small group of educators get together? What could they do, what could they make, what could they become? Not necessarily what you might think. This book describes an alternate journey, one that departs from the busy traffic of goal-oriented projects, over-determined aims, and the doorstep delivery of interventions in order to wander reflectively across a more expansive landscape. We came together to record the successes and failures of a small research project, witnessing it gather momentum and then dissipate, but always holding open the space for a nuanced way of working that allowed for � even celebrated � humour, deviation, distraction, and dissatisfaction. This is a record of that journey, told through story fragments and reflective commentary.
ANALISIS KEGAGALAN CURRENT TRANSFORMER (CT) TIPE DUA BELITAN SEKUNDER DENGAN INTI MAGNETIK TERPISAH PADA SISTEM PROTEKSI DAN PEMBATAS DAYA
Authors: Ilyas Iriandi , Agassy Muhamad Taufan
Published: May 2022

ABSTRACT

Current transformers function to transform large currents into small currents used for electrical energy measurement instruments, power limitation and protection of electric power networks, current transformers have many types, the use of current transformers in actual facts such as electrical power requested by consumers to producers of electricity providers at 53 kVA to 197 kVA using a single ratio current transformer type and> 197 kVA using a secondary twisting transformer type with a separate magnetic core In this type of current transformers with different ratios have different saturation values also due to high interference current values, so they are not able to provide an accurate secondary current value according to the class and the ability of current transformers against measuring instruments, power limitation and protection of electric power networksBy analyzing the failure of these types can be a reference or  reference in the use of current transformers by selecting the appropriate type, ratio and accuracy class on the electricity network
Uhakiki wa Nafasi ya TEKNOHAMA katika Kukuza Maudhui katika Tamthilia ya Kigogo
Authors: Mwangi Jackson Ndung’u
Published: May 2022

Fasihi ni zao la jamii na hubadilika kila uchao. Uwakilishi wa suala la TEKNOHAMA katika tamthilia za kisasa umechukua mkondo mpya. Hii ni kwa sababu, kutokana na jinsi dunia inavyobadilika ndivyo masuala ya kiteknolojia pia yanavyoathiri fasihi ya sasa na kuipa mguso na taathira mpya. Licha ya uwakilishi wa TEKNOHAMA kuwa na umuhimu katika kukuza fani na maudhui katika fasihi, mchango wake katika tamthilia ya Kigogo haujafanyiwa utafiti, suala linalomchochea mtafiti kulitafiti. Lengo kuu la utafiti huu ni kutathmini mchango wa TEKNOHAMA katika kukuza maudhui katika tamthilia ya Kigogo ya Pauline Kea (2016). Utafiti huu unaongozwa na Nadharia ya Uhalisia. Uteuzi wa sampuli utafanywa kimakusudi na utafiti wenyewe ni wa muundo wa kiudhamano. Mtafiti atasoma makala mbali mbali kuhusiana na mada na kisha kuichanganua data kwa njia ya kimaelezo
Analysis of Vitamin D and its Correlation with Interleukin-6 in COVID-19 Patients at Mary Begg Health Services, Zambia: Implication for Patient Management
Authors: Chileshe Misheck , Mulamba Mwamba , Julius Vernon , Kwangu Mwenya , Mubita Stephen Mwisiya
Published: May 2022

Introduction: The emergence of SARS COV-2 and Coronavirus Disease 2019 (COVID-19) came without any known medication or treatment, thereby raising concerns for drug (therapeutics) research and development. Vitamin D is a potent immunomodulator with a proven protective effect against respiratory viral infections, and because of this, many studies have been carried out to evaluate the effects of vitamin D on COVID-19 infection, however, with varying conclusions. Objective: To assess serum vitamin D levels and their correlation with IL-6 and other clinical characteristics among COVID-19 patients attended to at Mary Begg Health Services (MBHS). Methods: This cross-sectional study was conducted among COVID-19 patients at MBHS. The study included 33 confirmed severe patients admitted to the intensive care unit, 45 patients with mild symptoms, and 45 healthy controls. The Kruskal–Wallis test was used to compare the median serum vitamin D levels among the three groups, and Spearman’s correlations were performed to assess the correlation between serum vitamin D, IL-6, and clinical characteristics of the patients. Results: The majority of COVID-19 patients in this study had optimal levels of vitamin D 44/78 (56.4%), with vitamin D deficiency being observed in only 6/78 (7.7%). Vitamin D levels in the control group were not significantly different when compared to levels measured in severe and mild COVID-19 patients, median [IQR], 31.33 ng/ml [25.9-39.56] compared to 29.97 ng/ml [26.19-37.45] and 31.9 ng/ml [26.12-38.34], p = 0.916, respectively. Severe COVID-19 patients admitted to the intensive care unit were older and had median higher IL-6 levels (43.67 ± 11.86 years vs. 33.89 ± 13.38 years; p = 0.001 and 27.56 pg/ml [13.13-47.81] vs. 8.34 pg/ml [5.1-21.63]; p = 0.0003, respectively) than patients with mild disease. A significant negative correlation between vitamin D and IL-6 (r = - 0.42; p = 0.016) was found in severe COVID-19 patients. Conclusion: A negative (inverse) correlation between serum vitamin D and IL-6 was found in this study. Therefore, patients with severe COVID-19 might benefit from vitamin D supplementation, which would help to downregulate the cytokine storm and hence reduced disease severity.
Impacts and Causes of Flood Hazards on Public Health and Socio-Economic: The Case of Hirna Town, West Hararghe Zone, Oromia National Regional State, Ethiopia
Authors: Abrahim Shemsedin , Aliyi Michael , Ali Muhammad , Melese Tewekel
Published: May 2022

Introduction: Flooding is the most common destructive natural event globally. Aim: The goal of this study was to identify the causes of floods and their socio-economic consequences and public health. Materials and Method: The primary data collection methods were structured survey questionnaires, key informant interviews, focus group discussions, field observation, and document analysis. The survey questionnaires with 29 items were sent to 121 homes. The sample size for the house-to-house questionnaire survey was determined using the formula for sample size determination. Both probability and non-probability sampling techniques were used in this investigation. The data were summarized and analyzed using both qualitative and quantitative methodologies. The qualitative data gathered from key informant interviews, focus group discussions, and observation was interpreted, and the analysis was combined with survey findings to substantiate the outcome. Results: The lack of flood drainage infrastructure in the research area, according to 74.4 % of the homes, is the most important root cause of floods. Floods can increase the danger of waterborne pathogens and bug infections, with the most prevalent ailments experienced by the tested households being the common cold, malaria, diarrhea, and pneumonia. The lack of an early warning system played a significant role in exacerbating the flood damage. About (18.2%) claimed they were evacuated from their homes until the rainy season was over and back. The other (25.6%) diverged water flow direction and coping strategies to prevent flood impacts during flood events. Conclusion: One of the most prevalent illnesses observed in the houses surveyed was malaria. As a result, flooding is the most serious concern or hazard in the research area. Based on this analysis, the government should find a way to prevent flooding and drainage problems among the suspected areas. It is recommended that the watershed of the site should be delineated, and the streamline should be identified and managed properly.