bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Indigenous Non-Saccharomyces Yeast Strains with Potential Use in Winemaking
Authors: Castrillo David , Blanco Pilar
Published: January 2023

Background: The vineyard is a great reservoir of autochthonous yeast strains whose composition is defined by different regional (edaphology, orography or climatology) and anthropological factors (cultivation systems or cultural practices). Most of this yeast diversity corresponds to non-Saccharomyces strains, some of which have potential use in winemaking. Methods: The oenological potential of 29 different native non-Saccharomyces strains belonging to 4 species (Lachancea thermotolerans, Torulaspora delbrueckii, Starmerella bacillaris and Metschnikowia spp.) was evaluated, using the autochthonous Saccharomyces cerevisiae XG3 strain as a control. Microfermentations with pure culture of each strain were performed in duplicate and the basic parameters and major volatiles of wines were analysed following official methodology. The best strain within each species was selected using a quantification matrix including the relevant oenological characteristics. Results: The fermentative ability of non-Saccharomyces was lower than S. cerevisiae in all cases, but with differences among species. L. thermotolerans and T. delbrueckii showed higher fermentation rates than Starm. bacillaris, whereas Metschnikowia spp. presented a low fermentative power. At chemical level all non-Saccharomyces strains reduced the alcoholic content, the higher alcohols and the volatile acidity of wines and increased the content of glycerol, with differences among strains within a given species. T. delbrueckii and L. thermotolerans increased the total acidity of wines. The latter and Metschnikowia spp. strains produced lactic acid, which decreased the wine pH in the case of L. thermotolerans. According to their oenological traits the best rated strains of each species were Lt93, Td315, Mf278 and Sb474. In addition, the data obtained in pure fermentations were correlated to those chemical and aromatic compounds obtained with these non-Saccharomyces strains in sequential fermentations. Conclusions: Autochthonous strains of non-Saccharomyces yeast species contribute distinctive chemical characteristics to the wines. The correlations observed between wines fermented with the different non-Saccharomyces indigenous strains in pure and sequential fermentations suggest that their contribution to wine properties remains stable regardless of must composition or winemaking techniques.
Effects of Early Risperidone Treatment on Metabolic Parameters in Socially Isolated Rats—Implication of Antipsychotic Intervention across Developmental Stages of Schizophrenia
Authors: Tzeng Nian-Sheng , Yang Yu-Yin , Lin Chen-Cheng , Hsieh Po-Shiuan , Liu Yia-Ping
Published: January 2023

Background: Second-generation antipsychotics (SGAs) is thought responsible for the metabolic abnormalities of schizophrenic patients, however, some untreated schizophrenic patients had already developed problems with glucose metabolism. The present study examined the hypothesis that schizophrenia itself but not risperidone, an extensively employed SGA, is accountable for metabolic abnormalities. Methods: A 56-day risperidone regimen (1 mg/kg/day) was employed for rats of social isolation rearing (SIR) beginning at different developmental stage (28 or 56 days after weaning, i.e., adolescent and young adulthood, respectively). Metabolic parameters including body weight, systolic blood pressure (SBP), triglyceride, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol, and plasma glucose were measured at baseline, 28, and 56 days of the regimen. Oral glucose tolerance test (OGTT) was performed at the end of the regimen. Insulin function was evaluated by area under the curve (AUC) of OGTT, homeostasis model assessment-insulin resistance (HOMA-ir), and Matsuda index. Results: Our results demonstrated that: (i) SIR rats presented higher body weight, plasma triglyceride, and HOMA-ir than social controls. (ii) Higher insulin resistance was specifically presented in young adult rather than adolescent SIR rats. (iii) Adolescent drugged rats showed a lower level of LDL in day 28 of the regimen than young adult. Risperidone led to a lower LDL level in only young adult IR rats in day 56 than undrugged rats. (iv) SIR-induced dysregulation of insulin can be reversed by chronic risperidone treatment beginning at adolescence but not young adulthood. Conclusions: Our findings support the primary role of schizophrenia in metabolic abnormalities and risperidone appear beneficial when administered earlier.
SGLT2 Inhibition in Heart Failure with Preserved Ejection Fraction — The New Frontier
Authors: Aguiar-Neves Inês , Santos-Ferreira Diogo , Fontes-Carvalho Ricardo
Published: January 2023

Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome with high morbidity and increasing socio-economic burden, compounded by the lack of effective treatment options available to treat this disease. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have previously been shown to improve cardiovascular and renal outcomes in patients with type 2 diabetes and patients with heart failure with reduced ejection fraction (HFrEF). Recent major clinical trials with SGLT2 inhibitors, both empagliflozin and dapagliflozin, have now demonstrated improved cardiovascular outcomes in patients with HFpEF and a significant reduction in heart failure hospitalization. Current evidence shows a potential for cardiovascular benefits with SGLT2 inhibition that is consistent across the spectrum of ejection fraction, age, New York Heart Association (NYHA) functional class, natriuretic peptide levels and diabetes status. Although the cardioprotective mechanisms behind SGLT2 inhibition remain unclear, ongoing clinical studies aim to clarify the role of SGLT2 inhibitors on biomarkers of cardiac metabolism, diastolic function and exercise capacity in HFpEF. This article analyzes current clinical evidence from randomized controlled trials and meta-analyses and explores the potential cardioprotective mechanisms of SGLT2 inhibitors, while also looking towards the future of SGLT2 inhibition in HFpEF.
Treatment of Moderate Functional Mitral Regurgitation during Aortic Valve Replacement: A Cohort Study
Authors: Tiemuerniyazi Xieraili , Xu Fei , Song Yangwu , Nan Yifeng , Yang Ziang , Chen Liangcai , Zhao Dong , Zhao Wei , Feng Wei
Published: January 2023

Background: Treatment of moderate functional mitral regurgitation (FMR) during aortic valve replacement (AVR) is controversial. This study aimed to evaluate the effect of different surgical strategies in patients with moderate FMR undergoing AVR. Methods: A total of 468 patients with moderate FMR undergoing AVR from January 2010 to December 2019 were retrospectively studied comparing 3 different surgical strategies, namely isolated AVR, AVR + mitral valve repair (MVr) and AVR + mitral valve replacement (MVR). Survival was estimated using the Kaplan-Meier method and compared with the log-rank test, followed by inverse probability treatment weighting (IPTW) analysis to adjust the between-group imbalances. The primary outcome was overall mortality. Results: Patients underwent isolated AVR (35.3%), AVR + MVr (30.3%), or AVR + MVR (34.4%). The median follow-up was 27.1 months. AVR + MVR was associated with better improvement of FMR during the early and follow-up period compared to isolated AVR and AVR + MVr (p < 0.001). Compared to isolated AVR, AVR + MVR increased the risk of mid-term mortality (hazard ratio [HR]: 2.13, 95% confidence interval [CI]: 1.01–4.48, p = 0.046), which was sustained in the IPTW analysis (HR: 4.15, 95% CI: 1.69–10.15, p = 0.002). In contrast, AVR + MVr showed only a tendency to increase the risk of follow-up mortality (HR: 1.63, 95% CI: 0.72–3.67, p = 0.239), which was more apparent in the IPTW analysis (HR: 2.54, 95% CI: 0.98–6.56, p = 0.054). Conclusions: In patients with severe aortic valve disease and moderate FMR, isolated AVR might be more reasonable than AVR + MVr or AVR + MVR.
Rotational Atherectomy in Coronary Heart Disease Patients with Different Rotational Speed: In Hospital and Six-Month Outcomes
Authors: Wu Jiawei , Qiu Guangquan , Hu Hao , Ma Li-Kun
Published: January 2023

Background: Rotational atherectomy (RA) is an important technique for the management of severe coronary calcification. However, optimal rotational speed is yet to be defined. Methods: A total of 372 coronary heart disease (CHD) patients were retrospectively analyzed between February 2017 and January 2022. The patients were divided into four groups based on the maximum RA speed: group 1 (<150,000 rpm, 76 cases), group 2 (150,000 rpm, 156 cases), group 3 (160,000 rpm, 90 cases) and group 4 (≥170,000 rpm, 50 cases). The outcomes analyzed were procedural complications, six-months major cardiovascular and cerebrovascular events (MACCE) and chronic heart failure. Results: Patients in group 4 had a higher incidence of slow flow during the RA operation (p = 0.025). There was no significant difference in other complications among the four groups, as well as six-month MACCE. After adjusting for confounding factors, increase in rotational speed led to a higher probability of slow flow (p for non-linearity = 0.131; adjusted model) and MACCE (p for non-linearity = 0.183; adjusted model). Logistic regression analysis showed that rotational speed was a predictor of slow flow during RA operation (OR = 1.25, 95% CI: 1.05~1.49, p = 0.01). Moreover, the analysis demonstrated that individuals with lower rotational speed (<150,000 rpm) were at 230% higher risk of vasospasm compared with a higher rotational speed (160,000 rpm) (OR = 3.3, 95% CI: 1.08~10.09, p = 0.036). Conclusions: CHD patients treated with a rotational speed of ≥170,000 rpm had a higher risk of slow flow after RA. Rotational speed is an independent risk factor for slow flow in CHD patients. Moreover, a rotational speed of <150,000 rpm was associated with a higher risk of vasospasm compared with rotational speed of 160,000 rpm. There was no significant difference in six-month outcomes in comparison to elective CHD patients with different rotational speeds, and the probability of MACCE was intensified with increase in rotational speed.
Cardiorespiratory Fitness and Its Place in Medicine
Authors: Ross Robert , Myers Jonathan
Published: January 2023

The evidence that cardiorespiratory fitness (CRF) predicts morbidity and mortality independent of commonly obtained risk factors is beyond dispute. Observations establishing that the addition of CRF to algorithms for estimating cardiovascular disease risk reinforces the clinical utility of CRF. Evidence suggesting that non-exercise estimations of CRF are associated with all-cause mortality provides an opportunity to obtain estimates of CRF in a cost-effective manner. Together with the observation that CRF is substantially improved in response to exercise consistent with guideline recommendations underscores the position that CRF should be included as a routine measure across all health care settings. Here we provide a brief overview of the evidence in support of this position.
The Effects of Inspiratory Muscle Training (IMT) on Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery: A Systematic Review and Meta-Analysis
Authors: Zhang Sisi , Li Bo , Meng Xiaoping , Zuo Houjuan , Hu Dayi
Published: January 2023

Background: To determine the effects of inspiratory muscle training (IMT) alone on inspiratory muscle strength and endurance, pulmonary function, pulmonary complications, and length of hospital stay in patients undergoing coronary artery bypass graft surgery (CABG). Methods: We conducted a literature search across databases (Ovid MEDLINE(R) and Epub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily; Ovid Embase; Ovid Cochrane Central Register of Controlled Trials; Ovid Cochrane Database of Systematic Reviews; and Scopus) from inception to December 2021. The eligibility criteria were randomized controlled trials that investigated the effects of IMT versus usual care or sham IMT in patients undergoing CABG. Results: A total of 12 randomized clinical trials with 918 patients were included in the meta-analysis. Postoperative IMT was associated with improved maximal inspiratory pressure (MIP), maximum inspiratory pressure (PImax), and six-minute walking test (6MWT) and with a decrease in length of hospital stay (LOS). For preoperative IMT, there was statistical significance between intervention and MIP, PImax, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), postoperative pulmonary complications (PPCs), and LOS. Pre- and postoperative IMT resulted in improvements in MIP. Conclusions: Isolated IMT in patients who underwent CABG improved their inspiratory muscle strength and endurance, pulmonary function, and 6MWT and helped decrease postoperative pulmonary complications and the length of hospital stay.
COVID-19 and the central nervous system: What is the interplay?
Authors: Abd El-Fadeal Noha M , Anber Sara A , Elkot Hoda A , Maged Ghada , Saeed Iman A , Negm Marwa M , Abdelsamad Menna Allah , El-bakri Asmaa , Mohamed Wael
Published: January 2023

Since the outbreak of COVID-19 in 2019-2020, the highly contiguous disease caused by coronavirus 2 (SARS-CoV-2) spread worldwide in a short life span causing a disastrous effect and nearly 5.8 million deaths until February 2022. This global health crisis caused concerns about the disease's aetiology, epidemiology, and management. Understanding the virus's long- and short-term consequences on diverse human body organs and systems was one of the scientist's concerns despite the virus' respiratory system principal effect. Thus, after reporting neurological symptoms in approximately one-third of hospitalised patients with COVID-19, demonstrating how COVID-19 infects the central nervous system (CNS), causing neurodegenerative diseases in various patients and how the virus affects CNS function became quintessential. There are various mechanisms for COVID-19 pathophysiology, some implicating the potential virus invasion of the blood-brain barrier (BBB). Trans-synaptic and hematogenous routes are the main routes for the virus to pass through the barrier. Binding to the BBB endothelial cells is causing significant alterations in the permeability and integrity properties of the barrier, which cause an elevation of the incidence rate of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis among COVI-19 patients. COVID-19 patients developed neurological manifestations ranging from mild symptoms to severe diseases such as headache and loss of smell, encephalitis and CNS-mediated respiratory distress. However, encephalitis is not a common complication, and it has a significant mortality rate in severely ill patients due to the hyperactivation of the host immune response. Although more investigations are needed, severe COVID- 19 patients are considered at a high risk of neurodegenerative disorder as a long-term consequence of SARS-CoV-2 infection.
A Method for Fast Synchronization of Chaotic Systems and Its Application to Chaos-based Secure Communication
Authors: Nguyen Van Tho , Do Thanh Bao Ngoc , Mai Thi An Ninh , Nguyen Vy Rin , Le Dinh Dung
Published: January 2023

Chaos theory is one of the fields of research that has many practical applications. An important application of chaos in communication is that it can be used for secure communication. To be able to use the chaotic signal in communication, we need to synchronize the chaotic signal between the receiver and the transmitter. In this paper, a sliding mode controller is proposed for global synchronization between two chaotic systems. The interesting point of this controller is that it can help reduce the synchronization time based on the selection of the appropriate gain parameter. This method has also been applied to a secure communication system with chaos masking. Finally, numerical simulations are given to illustrate the effectiveness of the proposed method.
Implication of IFRS 17 on the Operationa
Authors: Gebreel Alia Youssef
Published: January 2023

Implication of IFRS 17 on the Operational Performance ofListed Insurance Companies in Nigeria
A single nucleotide variant on chromosome 3, rs6766334, distinguishes patients with normal-like breast cancer.
Authors: Mamoor Shahan
Published: January 2023

Molecular subtypes including the normal-like subtype drive patient outcomes in human breast cancer but the biological basis underlying subtype-specific disease is not completely understood (1-4). We mined published microarray data (5) to discover in an unbiased fashion the most distinguishing genetic features of tumors of each breast cancer molecular subtype. We identified a single nucleotide polymorphism on chromosome 3, rs6766334, as among the most significant genetic differences in the tumors of patients with normal-like breast cancer. Sequence variation at rs6766334 may be important in understanding differences in genetic background that favor development of normal-like subtype human breast cancer.
'Otaku: Japan’s Database Animals' review; Parasite Eve novel and film (Supplement I:17)
Authors: Akmut Camille
Published: January 2023

Supplement to the Historiography (of computer science and technology)
Merawat Ideologi Pancasila
Authors: Qosim Nanang
Published: January 2023

Pancasila merupakan ideologi negara Indonesia yang sudah disepakati secara komprehensif. Tetapi implementasi dan pengaplikasian Pancasila itu sendiri kurang didalam masyarakat kita. Mungkinkah tanpa adanya Pancasila negara kita ini dapat berdiri dengan sendirinya?Setiap negara memiliki ideologinya sendiri yang dibuat dengan maksud itulah bentuk dari identitas negara tersebut, misalkan saja negara Tiongkok dan Rusia dengan ideologi komunisnya, Amerika dengan ideologi liberalnya, kemudian Malaysia dengan ideologi sosialis liberalisme dan berbagai negara lainnya.Kita merupakan negara yang memiliki beribu macam suku, agama, ras, dan golongan beribu macam bentuk bahasa daerah, adat istiadatnya, beribu pulau dan lautnya, kekayaan hasil laut, dan daratnya. Maka untuk itulah para pendiri bangsa kita membuat Pancasila dengan tujuan agar semua perbedaan yang ada di negara kita ini dapat bersatu menjadi sebuah negara yang maju dan makmur.Setidaknya itulah yang menjadi dasar bagi masyarakat agar Pancasila dapat diamalkan didalam diri masyarakat itu sendiri, dengan begitu masyarakat dapat memberikan yang terbaik kepada bangsa dan negara.
A single nucleotide variant on chromosome 4 residing within IRF2 distinguishes patients with normal-like breast cancer.
Authors: Mamoor Shahan
Published: January 2023

Molecular subtypes including the normal-like subtype drive patient outcomes in human breast cancer but the biological basis underlying subtype-specific disease is not completely understood (1-4). We mined published microarray data (5, 6) to discover in an unbiased fashion the most distinguishing genetic and transcriptional features of tumors of each breast cancer molecular subtype. We identified a single nucleotide polymorphism, rs3733475, residing within IRF2, as among the most significant genetic differences in the tumors of patients with normal-like breast cancer. In a separate cohort of patients with normal-like subtype breast cancer, we observed transcriptome-wide differential expression of an IRF2 transcript. Analysis of patient survival data revealed that IRF2 primary tumor expression was correlated with overall survival in patients with basal-like breast cancer. Sequence variation in the IRF2 gene may be important in understanding differences in genetic background that favor development of normal-like subtype human breast cancer.
APPLICATION OF FIXED POINT THEOREM TO INSURANCE LOSS MODEL
Authors: Sakib S M Nazmuz
Published: January 2023

The future development when an insurance company is in a difficult circumstance can be described by a stochastic process which the insurance company is tasked to manage effectively in order to achieve best goal of the company. Application of an effective risk or loss management model in an insurance company brings in more revenue for the insurer and less conditional pay-out of claims to the insured. Insurance losses, risks and premium calculation or pricing have been active and essential topics in insurance and actuarial literatures but most of these literatures did not only stand the test of time due to dynamic nature of insurance principles and practices in highly evolving environment but also lack the intuitive and detailed standard rating logic to adjust loss rating to a particular experience. There is a need to strike a balance in charging an appropriate and equitable premium by applying a suitable loss model that gives a sufficient uniquely determined solution that will not necessarily put an insurer or the insured in an uncertain awkward business situations. Therefore, the objective of this research is to obtain sufficient conditions for convergence of algorithm towards a fixed point under typical insurance loss and actuarial circumstances to achieve a uniquely determined solution. At the end, a unique fixed point was determined and the algorithm formulated converges towards that point through straightforward and simplified generalised formulae and functions.
Resume "SISTEM EKONOMI MERKANTILISME"
Authors: Rahmadani
Published: January 2023

Merkantilisme adalah doktrin ekonomi yang berlaku di sebagian besar Eropa selama abad ke-17 dan 18. Merkantilisme termasuk dalam ‘prasejarah’ ekonomi, sebelum menjadi bidang studi. Merkantilisme adalah suatu teori ekonomi yang menyatakan bahwa kesejahteraan suatu negara hanya ditentukan oleh banyaknya aset atau modal yang disimpan oleh negara yang bersangkutan, dan bahwa besarnya volume perdagangan global teramat sangat penting.
Implementation of the Strictliability Principle in Enforcement of Environmental Civil Case Laws and Settlement of Their Execution in Indonesia
Authors: Warlia Meni , Munaf Yusri , Susilo Efendi Ibnu , Huda Ni’Matul , Thamrin S
Published: January 2023

Environmental degradation is a series of events from a decrease in environmental quality or a decrease in the carrying capacity of the environment caused by humans or caused by nature. In fact, environmental degradation will not only affect the degradation of the surrounding area or have an impact on direct victims, but will also affect other areas that still show the relationship of resource flows as we have witnessed together. This research is a doctrinal legal research that focuses more on primary and secondary legal materials. Research on doctrinal law itself can be carried out through an inventory of positive laws, tracing legal principles and doctrine, legal systematics, comparative law and legal history. The results of this study indicate that in environmental civil law cases, the combination of the concept of rule of law and the welfare state is very important, which consists of aspects of the rule of law and aspects of the legality of the concept of rule of law. The issue of social justice which is also the concept of a welfare state includes justice for the present generation as well as for future generations. Economic justice and state control rights over natural resources are very prominent factors in the form of the state's obligation to create general welfare and as much prosperity as possible for the people.
Panduan Mudah Memijahkan Ikan Koki
Authors: Dadiono Muh. Sulaiman
Published: January 2023

Ikan mas koki merupakan salah satu jenis ikan hiasair tawar. Ikan mas koki ini sangat potensial untukdikembangkan. Hal ini dikarenakan peluang bisnis ikankoki ini sangat terbuka lebar baik bisnis dalam negerimaupun luar negeri. Ikan mas koki memiliki nilaiekonomis tinggi. Budidaya ikan mas koki ini tidakmembutuhkan lahan yang terlalu luas. Siklusreproduksinya cukup singkat namun harga jualnya cukuptinggi. buku ini menjelaskan cara mudah dan cepat dalam memijahkan ikan koki
Capacity Building in Geo-information Sector: A Case of Kathmandu University
Authors: Ghimire Subash
Published: January 2023

Capacity building in Geo information is the empowerment that encompasses the ability, skills to initiate, manage, undertake, organize and evaluate Geoinformation activities. The capacity building includes major elements such as education, training, research, informal approaches such as networking, refresher courses, seminar/ conference. This paper aims to highlight the role of Kathmandu University (KU) for capacity building in Geo information sector in Nepal. It is committed to develop a center of excellence in Geoinformation sector by providing quality education, research, training etc. Kathmandu University, Geomatics Engineering program has collaboration with academic and nonacademic organizations to strengthen the quality of geoinformation education, research and internship. KU has also planned for the capacity building of faculty and students through its faculty development plan and student exchange program with other collaborating Universities. Geo spatial lab and other important advanced survey; Geodesy, remote sensing, photogrammetry lab etc. will be developed in near future at KU premises. LMTC and KU are also jointly establishing the necessary infrastructure required for the Geomatics Engineering program in the vicinity of these two organizations.
Necessity of Disaster Mapping Unit in Survey Department: The Context of 2015 Gorkha Earthquake and Disaster in Nepal
Authors: Shrestha Kalyan Gopal
Published: January 2023

N/A
Immediate Recovery Vision for Geo-information Sector in the Context of Post 2015 Earthquake Reconstruction
Authors: B.C. Krishna , Bhatta Ganesh Prasad , Shrestha Suresh Man , Manandhar Niraj , Marisini Anil
Published: January 2023

The devastating Earthquake 2015 has not only caused heavy loss of human lives and properties but also destructed the base of surveying and mapping. Maps and geoinformation are the foundation for resettlement and development activities whereas Geodetic Control Network is the fundamental base for all kind of mapping activities. Accurate and reliable Geoinformation is the foundation for any Post Disaster planning, resettlement activities, Disaster Risk Reduction and all kind of development activities. The Geodetic Network is the infrastructure of the infrastructures. For any development activities, mapping is a must and that the mapping to be of sufficient accuracy, the accuracy of Geodetic Network must be ascertained. Every developmental activities, reconstruction, rehabilitation, reconciliation processes require geoinformation and other census data. Successful implementation of this programme will ensure the reduction in data redundancy and ultimately reduces the time and cost for geo spatial data production.
Analysis Of 3D Cadastre Situation In Nepal
Authors: Paudyal Dev Raj , Sharma Rabin Kaji
Published: January 2023

The history of cadastre prevails that the records of land are kept in a text form as a basis to collect revenue and could be refer to one dimension cadastre. His Majesty's Government (HMG) of Nepal declared to launch Land Reform Program on 1964 AD. The main purpose of the program was to impose ceiling on land holding. For this purpose, it was necessary to determine the area of land hold by a land owner. In this way, the concept of two dimension cadastre was realized and the land registration was started with the help two dimension cadastral maps.As the population in urban area is ever growing and the land is fixed, the use of space under and above the surface seems to be one of the solutions to address the issue. So, there is a need of registration of vertical dimension of the legal status of real estate objects. The 3D information is becoming essential for land administration in Nepal. HMG of Nepal has adopted a policy to build apartments and joint residential building in urban area for optimal use of available space. Although, some juridical measures exist to address registration of vertical dimension of legal status of real estate objects in the available act, a lot of institutional and technical problems are facing for registration of apartment and room in a multi storey building in Nepal. Therefore, it is necessary to make a good institutional arrangement and develop a system to visualize 3D cadastre to link with cadastral maps and related land records.This paper first investigates the 3D cases practices in Nepal. There are more than eight such issues to be considered for the implementation of 3D cadastre. It then further elaborates about the three aspects; institutional, technical and legal to be considered for the 3D cadastre in Nepal. A low cost solution for the 3D mapping of the apartment or multistory building has investigated. The findings of this research will help the policy makers for the effective implementation of 3D cadastre in Nepal.
Monitoring Land Cover Change in Kathmandu City Using Spatial Metrics And Remote Sensing Techniques
Authors: Thapa Rajesh Bahadur , Murayama Yuji , Bajimaya Monika
Published: January 2023

This paper explores the urban land cover changes in Kathmandu city area in the past one and half decades. Multi-temporal satellite images and spatial metrics were used to quantify the land cover changes. The study area was setup to 10x10 km covering the Kathmandu metropolitan area. After pre-processing the satellite images, supervised classification with maximum likelihood classifier was applied to create thematic urban land cover maps. Random sampling method was used to create geographic points for each thematic map to assess the accuracy of the maps. Five land use classes: urban builtup area, cultivated land, orchard, water and natural vegetation were identified. For detecting land cover changes quantitatively, a land use land cover conversion matrix was computed between the year 1989- 1999 and 1999-2005. Spatial metrics (patch density, largest patch index, edge density, Euclidian nearest neighbor mean, contagion index and area weighted mean patch fractal dimension index) were computed to evaluate landscape structure of the metropolitan area.0The overall result shows rapid expansion of urban built environment and shrinkage of the agriculture land. The agriculture and orchard lands were mostly transformed into urban uses. The existence of water and vegetation were found very low as compared to other land covers. The urban expansion trend was confined in the peri-urban of the urbanized territory. The overall urban landscape seems to be very complex and fragmented in later years.
NSDI Initiatives in Nepal : An Overview
Authors: Bhatta Ganesh Prasad
Published: January 2023

Geospatial data, information and technologies are becoming more important and more common tools throughout the world because of their capacity to improve government and private sector decision making. Geospatial information is developed, used, maintained and shared in a various range of application areas. Sharing geospatial data in various applications helps to improve the management of public infrastructure and natural resources and further, it minimizes the duplication of resources invested in producing geospatial data. Many nations around the world are developing National Spatial Data Infrastructures (NSDI) to help facilitating cooperative production, use and sharing of geospatial information. In Nepal, NSDI initiatives have been taken through the National Geographic Information Infrastructure Program (NGIIP) under Survey Department, the National Mapping Organisation (NMO) of Nepal, since 2002. Due to various reasons, the NSDI initiatives in Nepal have not come to full functional stage yet. Various issues related to the development of full functional NSDI in the country are to be taken into consideration. This paper tries to give an overview of the state-of-the-art of the initiatives to suggest better way out for full functional NSDI in Nepal.
Macro-fungi diversity in Thulo Ban Community Forest of Arjam, Myagdi District, Nepal
Authors: Shrestha Shashi , Thapa Sadikshya , Jha Sanjay Kumar
Published: January 2023

Macro-fungi produce large fructifications that are visible without the help of a microscope. They play an important role in the conservation of forest ecosystems and biodiversity. The current study deals with the diversity of macro-fungi in the subtropical mixed forest of Arjam, Myagdi District. The study was conducted from June to September 2020, at a height of 1250 to 1450 meters above sea level. In three transects, 10 m×10 m quadrat was used and a total of 18 plots were made. A total of 70 macrofungal taxa were collected. Among them, 56 were identified at the species level, and 14 were generic levels belonging to 26 different families and 12 orders. The highest species-containing family was Russulaceae, with 16 species, whereas the densest species was Mycena sp., comprising 11.8 percent and Cantharellus cibarius was the most frequent species, consisting of 44.44 percent.
“Ukrainian wave” in the context of music life in modern Switzerland
Authors: Vardanyan Olga
Published: January 2023

Relevance of the study. The struggle of the Ukrainian people for freedom and independence has caused a great international wave of sympathy and, at the same time, interest in Ukraine and its artistic heritage. Intensification of cultural communication with other countries actualizes the need to understand the mechanisms of cultural life in Europe, the USA, other countries of the West and East. The study of the audience of classical music concerts is important because the listener is the final consumer of the music product. Studying the mechanisms of organizing a large international festival on the example of Lucerne Festival is important and promising.

Main objectives of the study. To highlight the problem of perception of Ukrainian music by the Swiss public and to describe the ways to overcome it in the context of the mechanisms of organization of musical life in Switzerland.

Methodology. The research is based on general scientific empirical (observation, description) and theoretical (generalization, comparison) methods. Statistical and sociological methods are used to identify patterns in the change of preferences of the European public in recent years.

Results and conclusions. The research summarized the experience of foreign scientists in studying the problem of audience aging. Some theories such as the theory of generations and the cohort effect are highlighted. Approaches to attracting new generations to the audience of classical music concerts are generalized. Problem areas in the perception of Ukrainian art by the European audience are identified and ways to overcome the problem are proposed.

Prospects for further research. The actual lack of research on the third link of the triad "composer — performer — listener" and the relevance of the object promotes further research in this area. Particular importance is the focus on foreign listeners, the search for ways to "translate" the meanings underlying the Ukrainian artistic product.
The timbre composition of Claude Debussy’s “Prélude à l’Après-midi d'un faune”: stylistic aspect
Authors: Zharkov Oleksandr , Kokhanyk Iryna
Published: January 2023

Relevance of the study. In the 20th–21st centuries art music the timbre component determines the processes of form creating, features of composition and dramaturgy, and becomes an essential component of a composer’s individual style system. This makes it necessary to distinguish and to define the concept of timbre composition, to study its functions in forming the text of a music work.

The purpose of the article is to study the timbre composition of “Prélude à l’Après-midi d’un faune” by Claude Debussy in the aspect of the composer’s individual style.

Methods. The methods of system and functional analysis are used, as well as the stylistic method, which gives possibility to determine the specific features of the timbre composition in the work.

The results and conclusions. The analysis of Debussy’s “Prélude à l’Après-midi d’un faune” score proves that the timbre composition clarifies the composer’s intention. The logic of the orchestral timbres changes is aimed at embodying the concept of dissolution, a gradual departure from the subjective through the dramaturgic idea of abandoning timbre solos (pure timbres), from the coloristics of one color to the diversity of all colors and shades, through the movement from pure timbre to doublings and mixes. The uniqueness of the composer’s timbre strategy is the chain of solos (flute — oboe — clarinet — violin — flute), which provides a colorful timbre development of the theme and the entire themes of the piece.

At the same time, the timbre composition deepens the three-part structure of the work. It is the timbre design that strengthens the gestural affinity of the themes and the gestural connections between the sections of the work. The study of the text confirms that the timbre composition–its exquisite structure, multilevel symmetry and perfection of proportions–reflects the main features of Debussy’s composing style. Even today, this work remains a source of inspiration for musicians of the 20th–21st centuries, who develop the timbral possibilities of sound, coloristic sound, and constructivism in the creating of music form. The experience of analyzing the timbre composition of “Prélude à l'Après-midi d'un faune” can be useful when studying modern art music works.
Institución del Conflicto Social: Violencias y Movilizaciones como Elementos para su Interpretación
Authors: DEL SOCORRO FOIO MARÍA
Published: January 2023

El artículo remite a diferentes corrientes de pensamiento y distintos autores sobre el problema del conflicto social. Se consideran teorías conflictivistas y teorías consensualistas, el enfoque funcionalista que relaciona la radicalización de los movimientos sociales con la incapacidad de las instituciones para integrar la protesta dentro de sus esquemas, y perspectivas centradas en el conflicto entendido como lucha por el poder. Se reconoce que a lo largo de la historia los actores sociales han mantenido en sus desplazamientos múltiples relaciones de complementariedad y antagonismo y que la forma que alcanza el conflicto al producir la movilización constituye la identidad de estos actores, y se destaca la importancia de la interpretación que los propios sujetos hacen sobre el conflicto. Se analizan conflictos que tienen lugar en las sociedades latinoamericanas y la necesidad de observar los sistemas políticos y las capacidades de los Estados para gestionar estos conflictos, y las tensiones que en Argentina dividen el mundo de las palabras, la ciudadanía y la participación del mundo de la precariedad y la represión y hacen de la discriminación la modalidad más extendida de violencia social. Concluye enfatizando la importancia de promover transformaciones constructivistas del conflicto para consolidar la democracia en nuestra región
Desigualdad entre establecimientos del comercio minorista mexicano en el contexto de COVID-19
Authors: Cantero Ramírez Margarita
Published: January 2023

El comercio minorista representa una fuente de empleo importante y sus establecimientos son espacios predilectos para el abasto para las familias mexicanas. Sin embargo, a partir de las medidas sanitarias implementadas se han propiciado condiciones laborales que evidencian diferencias entre los mismos, por ello se planteó como objetivo analizar cómo se da la desigualdad respecto a las condiciones laborales en el comercio minorista tradicional y moderno, por medio de un estudio cualitativo basado en una revisión narrativa de literatura. Entre los resultados sobresalen las acciones implementadas por comerciantes tradicionales y modernos para sobrellevar el cierre temporal de sus establecimientos comerciales, así como disparidades en el funcionamiento de los mismos. Se concluye en la necesidad de seguir reflexionando sobre las prácticas comerciales, laborales y sociales influenciadas por la relación capital-trabajo que van más allá del control individual y familiar.
TIEMPOS DE PANDEMIA DEL COVID-19, ACELERACIÓN DIGITAL Y EMPRENDIMIENTOS EN LIMA METROPOLITANA
Authors: SUÁREZ ROJAS Luis
Published: January 2023

En este artículo exploramos el modo como las personas se han apoyado sobre medios y plataformas digitales para el autoempleo y el desarrollo de emprendimientos, a fin de resistir la pandemia del COVID-19 en Lima Metropolitana. En este contexto, se ha dicho que los cambios introducidos por la cuarentena, como la educación a distancia y el trabajo remoto, exigen una alta dependencia de los medios digitales, estos cambios han venido para quedarse como parte del modus operandi de un sistema que busca reinventarse en tiempos de crisis.
PROGRAMACIÓN DE INTERFAZ GRÁFICA EN APP DESIGNER DEL MATLAB PARA REPRESENTAR LA SERIE DE FOURIER EN CURSO INTRODUCTORIO DE TELECOMUNICACIONES
Authors: HUAMANÍ NAVARRETE Pedro
Published: January 2023

This article describes the procedure for the implementation of a graphical user interface using the App Designer development environment of the Matlab software and its Toolbox Signal Processing and Symbolic Math, which allowed obtaining the Fourier Series coefficients for seven periodic signals followed by a graphical representation in the domain of time and frequency through pulses. Likewise, this 

interface was implemented using various components such as Drop Down, Button, Knob, Axes, among others, which allowed the choice of the number of sinusoidal components used in the decomposition, as well as the choice of the type of signal, its amplitude, frequency, DC level and duration time of the same. Therefore, this implementation complements the teaching-learning process developed remotely for a topic in the Telecommunications I course of the 6th academic semester of the Electronic Engineering Degree at Ricardo Palma University. Finally, the graphical results are presented for the case of four choices of periodic signals, with different amplitudes, frequencies and DC levels; as well as the numerical results in terms of the mean square error, showing a lower value for the triangular signal despite using a reduced number of sinusoidal components
INNOVACIÓN TECNOLÓGICA DESDE LAS INCUBADORAS EMPRESARIALES: FENOMENOLOGÍA PARA DOS PAÍSES EN VÍA DE DESARROLLO
Authors: ARGOTA-PÉREZ George
Published: January 2023

El objetivo del estudio fue analizar la innovación desde las incubadoras empresariales. Se aplicó una encuesta a seis consultores de la República de Cuba y doce docentes universitarios de la República de Perú donde se estructuró mediante una escala Likert, seis indicadores para su análisis: 1ro) servicio de prospectiva social tecnológica, 2do) mapa mental y decisiones a ejecutarse, 3ro) estrategia de investigación y desarrollo, 4to) codificación de innovaciones tecnológicas, 5to) Valor de creatividad empresarial, y 6to) análisis de emprendimiento. La validación fue, a través del coeficiente alfa de Cronbach. Se observó que, al menos tres preguntas no se aceptaron por los encuestados representando el 80%. El valor de la escala tipo Likert fue de 2,88 lo que significó, respuestas irregulares ante el conocimiento de las variables comunicación social, innovación e incubación empresarial. El valor del coeficiente alfa de Cronbach fue de 0,66 siendo la confiabilidad de buena. Los resultados indicaron limitaciones sobre el conocimiento que se relaciona entre la gestión social, el modelo de pensamiento desde la comunicación social hacia la innovación y las decisiones según el mapa mental que se orienta a las incubadoras empresariales.
MENTIRA E HISTORIA. LA CONCATENACIÓN DE SUCESOS BASADOS EN EL MENTIR POR ALGUNOS GOBERNANTES PERUANOS DEL SIGLO XXI
Authors: DE LA CRUZ VILLANUEVA Carlos
Published: January 2023

El siguiente ensayo histórico, tiene como fin describir un patrón de conducta social, mostrado a partir de ciertos acontecimientos, que concatenados revelan una manifestación social y característica compleja de algunos de los mandatarios del Perú en el siglo XXI. El comportamiento que analizaremos, bajo las aproximaciones de la historia de lo imaginario, será la mentira o algunos ejemplos de argumentos o proclamas dudosas que los mandatarios realizan. Este ejercicio de observación histórica, será de vital utilidad, para la comprensión e identificación de un patrón temporal acontecimental, sobre el cual se expresa, el uso de la mentira, como un mecanismo orientado a proteger la imagen del gobernante, siempre y cuando, el engaño generado no sea descubierto. Pues al ser evidenciado, se produce un escándalo, el cual se convierte en todo un acontecimiento histórico, que será el escenario de la destrucción de la imagen del gobernante, que al no puede ocultar la verdad de su actuar político será criticado y cuestionado por la población.
UNA MIRADA ANTROPOLÓGICA AL TURISMO CULTURAL EN EL MUSEO DE SITIO PUCLLANA
Authors: PAZ FLORES Gladys
Published: January 2023

El turismo produce cambios culturales significativos que implica una relación entre diferentes grupos socioculturales. En este sentido, la puesta en valor de los recursos culturales también ha diversificado los productos turísticos, segmentando el mercado en “Turismo Cultural”, donde se incluyen museos, sitios arqueológicos, galerías de arte y también la visitas a comunidades indígenas. Este estudio antropológico sobre este segmento, es fundamental para reconocer los aspectos y símbolos culturales, relaciones recíprocas entre los grupos, y el comportamiento de los actores en estos espacios. De esta manera, nos permite identificar conceptos teóricos y formas de interculturalidad, identidad y roles de ambos actores tomando como eje el análisis de las relaciones socios culturales, flujos de población y expresiones simbólicas en la interacción entre los turistas y anfitriones en espacios donde se expone nuestra riqueza cultural, como es el Museo de Sitio Pucllana.
ESTABLECIMIENTO DE UN SUBSTRATO BASADO EN RESIDUOS DE Cedrus sp., Eucalito sp. y Pinus taeda PARA EL CULTIVO DE Ganuderma lucidum
Authors: Quiñones Aguilar Mauro
Published: January 2023

Los recursos naturales han constituido siempre las principales fuentes para el desarrollode la economía de un país. Además, en los últimos años se ha logrado importantedesarrollo en la tecnología, que ha traído como consecuencia una explotación cada vezmayor de dichos recurso y residuos forestales que contamina el ambiente; razón por elcual, se plantea desarrollar sistemas de biotransformación para minimizar los efectosnegativos sobre el ambiente, mediada por Ganoderma lucidun, un Basidiomycete de lafamilia Ganodermateaceae, ampliamente reconocido por sus múltiples propiedadesmedicinales y nutraceúticas por siglos en China, Japón y Corea. Se logró establecer dostipos de medio de cultivo que permiten subcultivar, multiplicar y conservar el micelio a4°C. Convertir en semilla en trigo resbalado. Asimismo, se logró el desarrollo yfructificación de G. lucidum en residuos (aserrín) de la industria aserradora alto andinade eucalipto, pino y se descartó como substrato el de cedro, donde no se alcanzó lacolonización total del substrato menos la fructificación.
PRESENTACIÓN
Authors: Jacinto Pazos Pedro
Published: January 2023

os temores y las angustias se advierten cada vez más en el mundo de laglobalización neoliberal que vivimos. Ya no tenemos las incertidumbresde los graves conflictos que nos advertía la crisis del socialismorealmente existente y el capitalismo con su guerra fría extensa y,prolongada durante la última mitad del siglo XX. Hoy en día estamos cada vezmás atados a los sofisticados misiles y a la cibernética militar, que ya pareceser parte de nuestra naturaleza humana, donde la compasión y el sufrimientose presenta como nuestro dolor piadoso y religioso que ya no lo vemos comola perversidad del individuo o, de las personas que la realizan bajo sentidosde dominación y poder, sino como el salvavidas de nuestra ciudadanía. Todoslo manifiestan al unísono, desde el político de los países hiperdesarrolladoshasta el jerarca del tercer mundo que tiene bajo su merced su dominio y supertrecho también tercermundista.