bluuebunny/crossref_metadata_2025 huggingface dataset:
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
Authors: Zhang Wuji , Kedzierski Lukasz , Chua Brendon Y. , Mayo Mark , Lonzi Claire , Rigas Vanessa , Middleton Bianca F. , McQuilten Hayley A. , Rowntree Louise C. , Allen Lilith F. , Purcell Ruth A. , Tan Hyon-Xhi , Petersen Jan , Chaurasia Priyanka , Mordant Francesca , Pogorelyy Mikhail V. , Minervina Anastasia A. , Crawford Jeremy Chase , Perkins Griffith B. , Zhang Eva , Gras Stephanie , Clemens E. Bridie , Juno Jennifer A. , Audsley Jennifer , Khoury David S. , Holmes Natasha E. , Thevarajan Irani , Subbarao Kanta , Krammer Florian , Cheng Allen C. , Davenport Miles P. , Grubor-Bauk Branka , Coates P. Toby , Christensen Britt , Thomas Paul G. , Wheatley Adam K. , Kent Stephen J. , Rossjohn Jamie , Chung Amy W. , Boffa John , Miller Adrian , Lynar Sarah , Nelson Jane , Nguyen Thi H. O. , Davies Jane , Kedzierska Katherine
Published: May 2023

High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we found that Australian First Nations peoples elicit effective immune responses to COVID-19 BNT162b2 vaccination, including neutralizing antibodies, receptor-binding domain (RBD) antibodies, SARS-CoV-2 spike-specific B cells, and CD4+ and CD8+ T cells. In First Nations participants, RBD IgG antibody titers were correlated with body mass index and negatively correlated with age. Reduced RBD antibodies, spike-specific B cells and follicular helper T cells were found in vaccinated participants with chronic conditions (diabetes, renal disease) and were strongly associated with altered glycosylation of IgG and increased interleukin-18 levels in the plasma. These immune perturbations were also found in non-Indigenous people with comorbidities, indicating that they were related to comorbidities rather than ethnicity. However, our study is of a great importance to First Nations peoples who have disproportionate rates of chronic comorbidities and provides evidence of robust immune responses after COVID-19 vaccination in Indigenous people.
Dynamic patterns of electroosmosis peristaltic flow of a Bingham fluid model in a complex wavy microchannel
Authors: Hosham H. A. , Thabet Esraa N. , Abd-Alla A. M. , El-Kabeir S. M. M.
Published: May 2023

The purpose of this paper is to present a rigorous analysis of streamline patterns and their bifurcation to a viscoplastic Bingham fluid model that involves heat and mass transfer in an electroosmotic flow through a complex wavy microchannel. The Bingham fluid act as a solid medium in the core layer, which divides the channel into three distinct sections utilized to model the problem as a switched dynamical system between these zones. To track multiple steady states (stagnation points) and related trapping phenomena, we perform both analytical and numerical bifurcation analysis of each subsystem with respect to different physical effects such as electrical double layer thickness and Helmholtz-Smoluchowski velocity. The key feature of the technique presented here is its ability to reveal the peristaltic transport characteristics of the Bingham fluid model in the presence or absence of symmetric flow properties. The primary novelty here is the ability to regulate the location and stability of the equilibrium points in the domain of interest. This leads to the detection of global bifurcations that reflect important dynamic elements of the model. Our results highlighted a new category of complex behavior that controls transitions between qualitatively different transport mechanisms, as well as a class of non-classical trapping phenomena.
Anti-Toxoplasma gondii activity of Trametes versicolor (Turkey tail) mushroom extract
Authors: Sharma Homa Nath , Catrett Jonathan , Nwokeocha Ogechi Destiny , Boersma Melissa , Miller Michael E. , Napier Audrey , Robertson Boakai K. , Abugri Daniel A.
Published: May 2023

Toxoplasma gondii (T. gondii) infection continues to rise globally in humans and animals with high socioeconomic and public health challenges. Current medications used against T. gondii infection are limited in efficacy, safety, and affordability. This research was conducted to assess the higher fungi extract effect on T. gondii tachyzoites growth in vitro and possibly decipher its mechanism of action. Furthermore, we evaluated the extract's effect on human foreskin fibroblast viability. The methanol extracts of Turkey tail (TT) mushroom was tested against T. gondii tachyzoites growth using an RH-RFP type I strain that expresses red fluorescent protein throughout culture in a dose-dependent manner using a fluorescent plate reader. Similarly, we tested the effect of the extract on host cell viability. We observed that TT extract inhibited tachyzoites growth with a 50% minimum inhibitory concentration (IC50s), IC50 = 5.98 ± 1.22 µg/mL, and 50% cytotoxic concentration (CC50s), CC50 ≥ 100 µg/mL. It was discovered that TT extract induced strong mitochondria superoxide and  reactive oxygen species production and disrupted mitochondria membrane potential in T. gondii tachyzoites. Additionally, scanning electron microscopy depicted that TT extract and pyrimethamine (PY) caused a morphological deformation of tachyzoites in vitro. In conclusion, TT methanol extract made up of phytosterols, bioactive sphingolipids, peptides, phenolic acids, and lactones could be a promising source of new compounds for the future development of anti-Toxoplasma gondii drugs. Extracts were non-cytotoxic, even at higher concentrations.
Regioselective [3 + 2] cycloaddition of di/trifluoromethylated hydrazonoyl chlorides with fluorinated nitroalkenes: a facile access to 3-di/trifluoroalkyl-5-fluoropyrazoles
Authors: Zhang Nan , Ma Hai , Cheung Chi Wai , Zhang Fa-Guang , Jasiński Marcin , Ma Jun-An , Nie Jing
Published: May 2023

We describe the base-mediated [3 + 2] cycloaddition reaction of di/trifluoromethylated hydrazonoyl chlorides with fluoronitroalkenes for the synthesis of densely functionalized 3-di/trifluoroalkyl-5-fluoropyrazoles with potent biological activity.
Modulating living crystallization-driven self-assembly behaviors of oligo(p-phenylene ethynylene)-containing block copolymers and micellar stability by solvent and corona-forming chain length
Authors: Nie Jiucheng , Xia Longgang , Huang Xiaoyu , Lu Guolin , Feng Chun
Published: May 2023

Corona-forming chain length and solvent are vital factors that affect the micellar elongation mechanism to give micelles of different morphologies and stabilities. Necklace-like micelles can be obtainedviaend-to-end coupling of diamond-like micelles.
Adjacent atomic cobalt sites anchored on carbon foam as a self-supporting electrode for efficient hydrogen evolution
Authors: Wang Yingxue , Yu Jing , Zhu Jiahui , Liu Qi , Liu Jingyuan , Chen Rongrong , Li Rumin , Wang Jun
Published: May 2023

Based on the MOF derivation strategy of inkjet printing, carbon foam supported Co–N single atom catalysts was synthesized, which formed adjacent but dispersed Co single atom sites to promote hydrogen evolution.
Chemins de drainage-humidification d’un sol limoneux traité au ciment : étude expérimentale et simulations par le modèle de van Genuchten
Authors: Belal Tewfik , Ghembaza Moulay Smaine
Published: May 2023

Le présent article présente une étude expérimentale sur les chemins de drainage-humidification d’un sol limoneux traité à différents dosages en ciment et compacté à l’Optimum Proctor Normal à température ambiante. Les succions utilisées sont comprises entre 0,05 MPa et 342,63 MPa, et appliquées sur quatre formulations étudiées (sol naturel, sol + 2 % ciment, sol + 4 % ciment et sol + 6 % ciment). À la fin des essais sur les chemins de drainage-humidification, les courbes hydriques du sol traité à différents dosages en ciment nous permettent de déterminer les différents paramètres d’états du sol traité : degré de saturation (Sr), poids volumique sec (γd), indice des vides (e) et teneur en eau (w). La gamme d’imposition de succion ainsi que le dosage en ciment influencent de manière importante le comportement hydrique du matériau étudié. D’autre part, des simulations ont été effectuées en utilisant un modèle hydrique de la littérature ; ces simulations permettent d’illustrer l’effet du traitement sur les paramètres hydriques du sol étudié à savoir : la limite de retrait, la pression de limite de retrait et la pression de désaturation afin de faciliter l’interprétation des résultats expérimentaux obtenus.
Effect of powder reuse on physical, chemical and toxicological properties of 6061-Zr aluminum alloy processed by Laser Powder Bed Fusion (L-PBF)
Authors: Beal Maxime , Azzougagh Mohamed-Nour , Pourchez Jérémie , Bertrand Philippe , Cabrol Elodie , Si-Mohand Hocine , Keller Francois-Xavier
Published: May 2023

Laser Powder Bed Fusion (L-PBF) is an additive manufacturing process, which allows to produce metallic parts layer by layer. The reuse of the powder is critical for cost part. The reuse can modify the powder and thus the printed parts properties. This study is focused on a severe reuse of 6061-Zr by analyzing the physico-chemical features of the powder, their impact on both the printed parts and toxicological properties. The results of this study showed a high physico-chemical stability of 6061-Zr powder under severe reuse even if oxygen content increase on the reused powder. This study highlights the high amount of oxygen and the variation in chemical composition of the sieving residue. Besides, the toxicological properties of the powder and the mechanical features of the printed parts are unchanged. These results show that in addition to guaranteeing a specific particle size, sieving limits the oxygen increase and the chemical modification of the powder.
Analysis of the transmission path of factors influencing employee slackness in companies based on ISM-MICMAC
Authors: Yao Jianing , Zhang Ruizhi , Fan Kerou , Yan Yu
Published: May 2023

Employee slackness is a prevalent behavior among current corporate employees, and this behavior harms both employee personal development and organizational effectiveness. In this study, factors are extracted from four levels: employee, leader, company, and job, and the relationships of factors influencing employee slackness are sorted out using the explanatory structural model (ISM) and the cross-influence matrix multiplication method (MICMAC), and corresponding conclusions are drawn based on the relevant mechanistic models. The results of the study show that a strong sense of overqualification and less meaningful work as independent group factors have the deepest influence on corporate employees to produce slacking behavior. The findings of this study help enterprises to understand the influencing factors of employees’ slacking behavior at a deeper level; they also provide important management insights for enterprise managers to pay attention to and alleviate employees’ slacking emotions and negative work behaviors.
Risk Path Identification and Research of Digital Trade Enterprises Based on the DEMATEL-ISM-MICMAC Model
Authors: Lv Haofeng
Published: May 2023

As the world ’s largest trading country, it is very important to ensure the stable operation of digital trading enterprises in the digital economy. Therefore, it is necessary to study the identification and influence path of risk factors. Based on the literature analysis method and expert interview method, this paper determines 18 risk factors of digital trade enterprises, and then divides the risk into two dimensions of internal and external factors to form the risk path identification index system of digital trade enterprises. The DEMATEL ( Decision Making Trial and Evaluation Laboratory ) -ISM ( Interpretative Structure Method-Cross-Impact ) -MICMAC ( Matrix Multiplication Applied to Classification ) method was used to quantitatively reveal the comprehensive influence degree of each influencing factor. And the reason degree and centrality of its impact on the risk of China ’s digital trade enterprises are divided into strong ( weak ) driving type according to the value of reason degree greater than zero ( less than zero ). Further analysis of the hierarchical structure and overall influence relationship of the risk factors of China ’s digital trade enterprises, the causes of the seven levels of China ’s digital trade enterprise risk are obtained. Then, combined with the dependence of each key risk factor and the size of the driving force, the risk factors are divided into four quadrants, and the interaction between the risk factors is revealed. The results show that the key factors affecting enterprises are financial risk, decline of digital trade, increase of trade barriers, aggravation of digital financial risk spillover and aggravation of supply chain crisis. Based on the algorithm, this study identifies the risk factors and ways that affect Chinese digital trade enterprises. The research results can provide theoretical risk path guidance for the risk management of enterprise risks, and provide scientific decision-making basis for enterprises when facing risks.
Study on the optimization path of Liaoning trade structure under the background of “anti-globalization”
Authors: Zhang Yan
Published: May 2023

Through the “inverse globalization” influence on trade structure and factor endowment theory in Liaoning trade structure, from strengthening the attention of trade friction in Liaoning, Liaoning export market structure, develop scientific and reasonable trade development strategy, Liaoning support countries and Liaoning key enterprises put forward “inverse globalization” under the background of Liaoning trade structure optimization path.
Research on the reconstruction of northeast local cultural ecology by New Media
Authors: Cao Yingmei
Published: May 2023

The emergence of new media makes the northeast local culture ecological reconstruction, this paper through the background of northeast local culture development, the analysis of new media on the significance of northeast local culture ecological reconstruction and motivation, explore new media of northeast local culture ecological reconstruction path, and promote the efficient spread of northeast local culture. Rural construction is an important content of socialist modernization construction, and local culture is also the key point of rural construction is also the difficulty, but also the soul. In recent years, with the large increase in the number of rural Internet users in northeast China, a large number of rural Internet users are not only the audience of new media, but also the communicators of new media. They use new media (TikTok, Kuaishou, Toutiao and other network platforms) to release the latest life trends around them. The rural local culture communicators using new media show content including rural food, local products and rural production and living such as local culture, shows the new era of the new look of the new rural construction in our country, become an important part of the new era of rural network culture, but also the reconstruction of local cultural ecological in northeast China. Therefore, studying new media is of great significance to the reconstruction of rural cultural ecology in northeast China.
Research on Influencing Factors of Coordinated Development of Regional Economy Based on City-country fringe Income Gap
Authors: Lin Jia
Published: May 2023

At present, China is affected by the decline of international market demand, and the export growth rate is slowing down, so it is urgent to rely on domestic demand to stimulate economic growth. The widening income disparity intercity and countryside is not conducive to releasing the consumption power of rural residents and building a harmonious society in China today. The regional economic development gap is a universal and international problem in the process of economic development in all countries of the world, which has always been concerned by all countries of the world. The existence and expansion of regional economic development gap will inevitably have a great impact on the economic development and social stability of various countries (or regions). This paper mainly focuses on the problem of city-country fringe income disparity between regions. First, it makes a comparative analysis of the city-country fringe income disparity between regions in China. In the analysis of the income composition of urban and rural residents, it is found that the wage income disparity has the largest contribution to the overall income disparity intercity and countryside; Although the contribution rate of operating income is negative, the role of operating income disparity in narrowing the overall income disparity intercity and rural residents is decreasing; Property income accounts for a small proportion of urban and rural residents’ income, and its contribution rate is low; The transfer income disparity has a large contribution rate to the city-country fringe income disparity, which is due to the long-term city-country fringe division in China.
Research on the Mechanism of the Impact of M&A Motivation on M&A Performance
Authors: Zhao Yuchen
Published: May 2023

Under China’s financial supervision system, the financial industry gradually tries to merge and acquire in order to achieve the strategic goal of industrial integration and economic transformation, and maintain a state of continuous rising profitability. M&A, as an important means to reallocate resources in the capital market, has a far-reaching impact on enterprises and is also a hot issue in the field of corporate finance research in recent years. Because of the complexity of M&A activities, the identification of M&A motives is particularly important for the study of M&A performance and related issues. However, the previous research lacks a systematic study of M&A motivation and its influence on M&A performance from the perspective of “agent”. Therefore, based on the existing M&A theories and the actual situation in China, this article studies the relationship between managers’ agent M&A motivation and M&A performance from the perspective of “agents”. This article innovatively introduces a compensation mechanism to study the impact of agent M&A motivation on M&A performance, which can obtain whether agent M&A motivation damages corporate value, and can also understand whether executives seek private benefits through M&A, providing evidence for the agent motivation hypothesis from multiple perspectives.
The Effect of Elderly’s Social Engagement on their Emotion
Authors: Liu Siyuan
Published: May 2023

The mental health problem of middle and old people cannot be ignored, while depression is a common but serious mental illness that affects the health of the elderly. In order to find the optimal social activity which seniors would like to do to decrease their depression, this research employed 5 different models onto elderly longitudinal study from 4 different countries. Based on database analysis and detailed interpretation, the research found suitable approaches to prevent senior depression in different countries and communities.
Sector rotation multi-factor stock selection strategy based on six boards
Authors: Chen Xinrui , Ma Cenyi , Zhao Mengzhu , Guo Yenan , Xu Jiaye
Published: May 2023

This paper proposes an investment strategy based on a regression linear model to predict sector rotation and a multi-factor scoring model to select stocks to achieve excess returns. The strategy uses January 2006 December 2020 as the model construction period and January 2021 June 2021 as the model validation and backtesting period. Using Shenyin & wanguo’s industry classification as a standard, the cyclicality of industries is classified by β value and the existence of sector rotation is verified using the difference in rate of return between cyclical and non-cyclical industry. The factors associated with the annualized rate of return are selected and the fitted formula for the annualized rate of return is obtained by regressing linear equation and neural network multidimensional correlation to select the dominant board. Valid factors for each board were selected for fitting, and the factors were assigned weights for scoring, resulting in 32 stocks. The backtest results significantly outperformed the CSI 300 Index, and the model performance is stable and can achieve better returns.
Leveraging Overseas Crowd-sourcing Resources in the Foreign Trade Industry: Opportunities, Challenges, and Supply Chain Management Considerations
Authors: Wang Jianbo , Jiang Zisu , Wang Hang
Published: May 2023

This study examines the use of overseas crowdsourcing resources in the foreign trade sector to boost efficiency and reduce costs in the post-pandemic era. We evaluate potential opportunities and challenges in sales order management, logistics, and online dispute settlement, all while considering the effects of crowdsourcing partnerships on the management of the supply chain. Foreign trade companies can improve their operations and utilize the potential of a globally applicable crowdsourcing resource application system to meet the needs of the post-epidemic period.
Construction and Empirical Analysis of the Index System of High-quality Development of Manufacturing in China
Authors: Yuan Huiai , Zhao Lihong
Published: May 2023

Promoting high-quality development of manufacturing is not only an important part of promoting high-quality economic development, but also an inevitable requirement for deepening supply-side structural reform, as well as an objective requirement for comprehensively building a great modern socialist country. Based on the basic requirement of manufacturing high-quality development, this paper builds evaluation index system from two dimensions of “source” and “fruit”, containing six secondary indicators: innovationdriven, intellectualization-driven, service-driven, high added-value, high productivity, high efficiency. Then, we measure the high-quality development level of 30 provinces and 27 manufacturing sub-industries in China from 2011 to 2019 by using the ″Vertical-Horizontal″ Wide Range. We find that the overall high-quality development level of manufacturing industry is on the rise; By region, the high-quality development level of manufacturing industry is normally distributed, showing obvious regional heterogeneity of “strong east and weak west”. By industry, the sub-industries of the manufacturing industry have improved their high-quality development level to varying degrees, showing a good development trend. However, most of the molecular industries in China’s manufacturing industry are at a lower level, and only a small part is at a higher level. Based on this, the path of high-quality development of manufacturing industry lies in encouraging enterprise innovation, promoting supply-side structural reform, highlighting the integrated development of industries and driving intelligent manufacturing.
Re-orienting China-Australia Relations in the Theoretical Perspective of Security Dilemma
Authors: Zhang Xuefei , Wang Zihan
Published: May 2023

China and Australia have maintained good economic and trade relations in the 21st century. However, since 2018, the Australian government has re-oriented its attitude towards China and provoked Sino-Australia trade friction regardless of its economic interests. This thesis provides a new perspective to explain the deterioration of China-Australia relations from security dilemma theory. Australia views China as a political and economic threat due to the consideration of geopolitics and export dependency, thus adopting policies against China. Accordingly, after going through stages of suspicion and warning, China took action against Australia. Consequently, China and Australia sank deeper and deeper into a security dilemma. A systematic study of China-Australia relations helps explain the Australian government’s perverse moves and provides theoretical support for peace and security in the Asia-Pacific region.
Detailed Review of Stagflation and Recession
Authors: Liu Yuhao
Published: May 2023

This paper thoroughly analyzes stagflation and recession along with their causes, effects and approaches to resolve them. Detailed literature on stagflation and recession provides value added analysis. In-depth review provides analysis about the history of stagflation, its effects and approaches to solve it. In addition, detailed reviews of recession, causes of major recessions, major sources of pressure for recession are thoroughly covered. Findings suggest that economies cannot completely avoid stagflation and recession, but they can reduce the effect of these factors on the economy.
ESG Ratings and Corporate Value
Authors: He Yuxin
Published: May 2023

ESG as a concept advocates companies to pay more attention to environmental friendliness, social responsibility and corporate governance in their development process. Companies can attract investment and enhance their competitiveness by developing ESG concepts. Based on the data of Chinese listed companies for five years from 2017 to 2021, relevant indicators are constructed, and regression analysis is conducted on them using static panel models to empirically investigate the impact of ESG performance on corporate value. Specifically, this study documents a significant positive relationship between ESG performance and corporate value. The results still largely hold after a robustness checks, including alterative measure of corporate value. This study contributes to the existing literature on the economic consequences of ESG and provides implications for both researchers, investors, and practitioners.
Maternal Education and Their Offspring’s Income in China
Authors: Xia Ziqing
Published: May 2023

In this paper, I study the relationship between maternal education and offspring income higher education are more likely to cultivate offspring with higher education. Using 2012 and 2014 China Labor Force Dynamics Survey, I find that one year increase of maternal education is associated with a 1.7% increase in children’s income. In studying the mechanism, I suggest that maternal education improves offspring’s income via improving children’s education. Hence, I conclude that women with a strong individual educational background devote more time and energy to their children. Consequently, their offspring earn a higher income.
Enhancing predictive accuracy of asset returns by experimenting with ML techniques
Authors: Pandey Prachi , Bandaru Abhijitha
Published: May 2023

The unparalleled success of machine learning is indisputable. It has transformed the world with unimaginable solutions to insistent problems. The remarkable accuracy that machine learning manifests for making estimations is an object of fascination for plenty of researchers all over the world. The financial industry has also benefited from the growth of this electrifying field to predict asset returns, creditworthiness of a customer, and portfolio management, among others. In this research, we spotlight how this accuracy is contingent upon the analysis of various aspects of the data. We also experiment with simple techniques to make predictions and our findings suggest how these methods overshadow neural nets. The results indicate that the penalized linear models deliver the best performance. Random forest models had not been effective though. Machine learning models fitted with respect to median quantile loss were similarly observed to typically offer improvements across all machine learning models across all loss metrics. While little is known about the future of asset return that involves various risk and uncertainty, the recent enhancements in a machine learning field can contribute to deep domain training. Machine learning is increasingly gaining popularity nowadays in sectors including engineering, charity work, etc. Recently, even behavioral economics has started to leverage machine-learning expertise.
Exploring Solutions to the Conflict between the Ownership of Trust Property and the Numerus Clauses
Authors: Jin Wanyi , Li Yijia
Published: May 2023

The principle of numerus clauses is the basic principle of civil law countries, and trusts, as a product of the common law system, are bound to diverge from it. Among them, the conflict between the ownership of trust property and the numerus clauses is the most significant. How to ease the conflict between the two in order to promote the long-term development of trusts in China has attracted a lot of attention. Trusts are developing rapidly around the world, and a comparative study approach has been adopted, of which the following are representative views: (i) Japanese scholars consider that trust is a legal relationship with both jus in rem and obligations, and thus hold the view that trust property has both owner’s right and creator’s right. (ii) the common-law scholars deem that the legal nature of a trust is that the trustee and the beneficiary share the ownership of the trust property, namely dual property rights, which is a kind of “ a bundle of rights “. This article argues that the contradiction between the ownership of trust property and the legal principle of property rights can be alleviated by strengthening the practical regulation and the improvement of the relevant laws based on the essence of trusts, which are based on trust.
Proposals on prc’s company classification by the comparative method
Authors: Li Yijia , Jin Wanyi
Published: May 2023

With the constant development of companies in our country, we still classify companies exclusively on the ground of person cooperation or capital integrity since the promulgation of the PRC’s Company Law(CCL) in 1993. Classificatory standard like this lagged far behind and exposed many problems, which includes the loopholes in the corporation regulations, state-funded companies types are excluded in this standard, and always not conducive to the boosting domestic company competitiveness among the fierce international competition. By comparing experiences of other countries and judicial districts, this article discusses the improved approaches: Adopting the company classification standard based on shares publicly offered and transferred, making specific classified pathways of existing companies, which means revising the Company Law and the Securities Law jointly.
Comparing various GARCH-type models in the estimation and forecasts of volatility of S&P 500 returns during Global Finance Crisis of 2008 and COVID-19 financial crisis
Authors: Chen Xuanyu
Published: May 2023

In this study, we utilize various GARCH-type models to estimate and forecast volatility on S&P 500 returns and compare the results between the two financial crises, the GFC of 2008 (Global Financial Crisis of 2008) and the COVID-19 financial crisis. These two financial crises are different from the forming reasons by whether mainly caused by the financial factors. This study also makes the evaluations on the performance of these GARCH-type models in estimating and forecasting volatility, which may provide the efficient models for reference for the research of the volatility of the future potential financial crisis. We find that as for the AIC/BIC assessments on the estimation of volatility, the GJR-GARCH model performs better during the GFC of 2008, while the EGARCH model has the better performance during the COVID-19 financial crisis. With respect to the QLIKE loss function evaluation on the forecasting ability of volatility, the GJR-GARCH model performs better during the GFC of 2008, while symmetric GARCH model has better volatility forecasting ability during the COVID-19 financial crisis.
Analysis of Emergency Management of the Internet Public Opinion on Public Emergencies
Authors: Nie Xitong
Published: May 2023

With the continuous development and progress of China’s economy and society, the government also attaches more and more important to the enthusiasm and initiative of the public to participate in political life. As China is in a period of transition, various conflicts are highlighted, and the rapid development of Internet technology makes it easy to attract the large-scale attention of netizens and quickly form a strong public opinion field after the occurrence of public emergencies. Hence, how to effectively respond to and guide Internet public opinion on public emergencies has become one of the critical issues that governments at all levels need to address. This paper takes public emergencies as the research object and discusses their concepts and characteristics from the theoretical point of view; explains the current situation of the Internet public opinion on public emergencies in China and its causes; focuses on analyzing the problems and causes of the current emergency disposal of the Internet public opinion on public emergencies in China; and finally proposes specific measures to improve the construction of the emergency management system of the Internet public opinion on public emergencies in China.
Research on Predisposition and Perceived Function of the Third-person Effect-A Case Study of the Zero Sugar Drinks Advertisement
Authors: Gao Suya
Published: May 2023

The sugar-free beverage advertisement emerged in 1980s. Recently, with the general health trend disseminating away, sugar-free beverage consumption has become a new fashion among the youth, of which the advertisement spread on social media has increased its effects in the Gen Z. While it has been extensive and unique on the aspect of advertising, this papaer mainly revealed that the methods of text analysis and literature analysis have been applied here, for what has been explored to depict how the third-person effect did work on explaining the advertising communication of sugar-free beverages. This paper finds that the path of advertising attaches importance to attracting the audience with the third-person effect, which directly affects other types of beverage advertisements. This paper depicts that the main value is to provide reference or other kinds of contribution to the research on beverage advertising.
Lymphological Liposculpture for Secondary Lymphedema after Breast Cancer and Gynecological Tumors: Long-Term Results after 15 Years
Authors: Cornely Manuel E.
Published: May 2023

Background Untreated lymphedema of an extremity leads to an increase in volume. The therapy of this condition can be conservative or surgical.

Methods “Lymphological liposculpture” is a two-part procedure consisting of resection and conservative follow-up treatment to achieve curative volume adjustment of the extremities in secondary lymphedema. This treatment significantly reduces the need for complex decongestive therapy (CDT). From 2005 to 2020, 3,184 patients with secondary lymphedema after breast cancer and gynecological tumors were treated in our practice and clinic. “Lymphological liposculpture” was applied to 65 patients, and the data were recorded and evaluated by means of perometry and questionnaires.

Results The alignment of the sick to the healthy side was achieved in all patients. In 58.42% (n = 38), the CDT treatment could be completely stopped postoperatively; in another 33.82% (n = 22) of the patients, a permanent reduction of the CDT was achieved. In 7.69% (n = 5) patients, the postoperative CDT could not be reduced. A total of 92.30% (n = 60) of the patients described a lasting significant improvement in their quality of life.

Conclusion “Lymphological liposculpture” is a standardized curative sustainable procedure for secondary lymphedema for volume adjustment of the extremities and reduction of postoperative CDT with eminent improvement of the quality of life.
Mobile Health-Technology-Integrated Care for Atrial Fibrillation: A Win Ratio Analysis from the mAFA-II Randomized Clinical Trial
Authors: Romiti Giulio Francesco , Guo Yutao , Corica Bernadette , Proietti Marco , Zhang Hui , Lip Gregory Y. H. ,   on behalf of the mAF-App II trial investigators
Published: May 2023

Background The Mobile Health (mHealth) Technology for Improved Screening and Optimized Integrated Care in atrial fibrillation (AF) (mAFA-II) cluster randomized trial assessed the efficacy of an integrated care approach in improving the prognosis of AF patients. In this study, we provide a reanalysis of the trial outcomes using the win ratio (WR) approach.

Methods The mAFA-II trial allocated patients to receive a mHealth-technology implemented Atrial Fibrillation Better Care (ABC) pathway (mAFA intervention) or usual care. The primary outcome was the composite of all-cause death, ischemic stroke or systemic thromboembolism, and rehospitalization. The efficacy of the mAFA intervention was analyzed according to the WR method using the unmatched pairs approach, with the components of the primary outcome analyzed hierarchically as follows: (1) all-cause death; (2) ischemic stroke or thromboembolism; (3) rehospitalization. Results were reported as WR and 95% confidence intervals (CIs). In addition, we calculated win odds (WO) and 95% CI.

Results A total of 3,324 patients were enrolled in the mAFA-II trial and included in this analysis (1,646 allocated to mAFA intervention and 1,678 to usual care). Among 2,761,988 unmatched pairs comparisons, the number of wins was higher in the mAFA intervention group, with a WR: 2.78 (95% CI: 1.85–4.17). WO confirmed the effect of mAFA intervention, although with a lower magnitude (WO: 1.06; 95% Cl: 1.04–1.08).

Conclusion In this posthoc WR analysis of the mAFA-II trial, a mHealth-technology-implemented integrated care approach was effective in reducing the risk of the primary composite outcome of all-cause death, ischemic stroke or thromboembolism, and rehospitalization, even when prioritizing fatal events.
The societal role of meat: the Dublin Declaration with an Australian perspective
Authors: Pethick David W. , Bryden Wayne L. , Mann Neil J. , Masters David G. , Lean Ian J.
Published: May 2023

It is clear that the societal role of meat is being challenged with ideological and simplified logic without substantiation from robust data-driven science. With this background, the international summit titled ‘The societal role of meat – what the science says’ was held in Dublin, Ireland, during October 2022, to provide evidence-based evaluations and the Dublin Declaration was signed by over 1000 scientists. In this paper, we provide a synopsis of the summit and then give context for evaluating the societal role of meat in Australia. The key themes of the summit were the essential roles of meat in (1) diet and health, (2) a sustainable environment and (3) society, economics and culture. Evidence clearly showed the role of meat as a nutrient-dense source of high-quality protein and micronutrients that can be safely consumed by humans. Further, the complementary role of livestock in agricultural systems was highlighted with both plant- and animal-based agriculture reliant on each other to maximise the efficient production of food. Thus, from both an Australian and world perspective, very little food considered to be human-edible is fed to livestock. The role of livestock in rural societies across the world was emphasised to underpin regional and national economies, with particular importance in those countries with developing economies to facilitate growing wealth to ‘step out’ of poverty and provide gender equality. Meat production, particularly from ruminants, is a critical part of Australian primary production and it is concluded that the Dublin Declaration is highly relevant to Australia. Finally, concern regarding future funding and organisation of research and extension is discussed. There is a need to continue funding highly collaborative programs that bring a broad range of disciplines together, in conjunction with undergraduate and postgraduate teaching to underpin the social license to operate for meat and livestock production.
New Zealanders with low back pain seeking health care: a retrospective descriptive analysis of Accident Compensation Corporation-funded low back pain healthcare service usage
Authors: Hill Julia , Kay Dylan , Gordon Jacob , Niazi Imran Khan , Saywell Nicola
Published: May 2023

Introduction Most New Zealanders experience low back pain (LBP) at least once throughout their lifetime and many seek help from the large range of health providers in primary care. Accident Compensation Corporation (ACC) funds a significant proportion of those claims, but which services are they funding and what are the costs? Method This was a retrospective audit and descriptive analysis of ACC-funded, non-public hospital healthcare service use by people with LBP in New Zealand (NZ). Outcome measures were the healthcare services accessed by people with ACC-funded LBP,the claims (all occurrences for a service that has generated a payment/year), single contact (with a service), and costs (NZ$) for services between 2009 and 2020. Results The number of claims for services were 129 000 for physiotherapy, 105 000 for general practitioner and 59 000 for radiology services. Per single contact, elective surgery and radiology services were the most expensive. During 2009–2020, there were 3.3 million ACC claims for LBP with a total cost of NZ$4 billion. Over this time, there was an increase in claims, costs and single contacts. Costs decreased slightly during 2010 due to changes in healthcare funding and in 2020 due to the COVID-19 pandemic. Discussion Consumers have considerable choice in where they access health care for ACC-funded LBP services. This study shows the services they use most frequently and the cost to NZ for those services. These data can inform service planning for ACC-funded LBP health care in NZ.
A corpus-driven description ofoin Naijá (Nigerian Pidgin)
Authors: Manfredi Stefano , Čéplö Slavomír
Published: May 2023

Widely attested in both creole and non-creole languages of the Atlantic basin, the function wordohas been traditionally described as a ‘sentence/phrase final particle’, owing to its typical syntactic behaviour, rather than to its multiple grammatical meanings. Based on the corpus-driven analysis of the NaijaSynCor, a ~400K words corpus of spoken Naijá (i.e., Nigerian Pidgin), this study suggests that sentence-finalocan be better described as an ‘illocutionary force indicator’ whose main pragmatic function is to modify the illocutionary force associated with directive and assertive speech acts. The study also provides evidence for the emergence of new coordinating and subordinating functions ofoin intra-sentential position that are semantically harmonic with its assertive (i.e. epistemic) meaning in sentence-final position. The corpus-driven analysis further shows that the higher occurrence of sentence-finaloin (formal and informal) dialogic texts in comparison to monologic texts is a reflex of its basic illocutionary function.
Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial—outcomes of the Opti-med study
Authors: Etherton-Beer Christopher , Page Amy , Naganathan Vasi , Potter Kathleen , Comans Tracy , Hilmer Sarah N , McLachlan Andrew J , Lindley Richard I , Mangin Dee
Published: May 2023

Background

potentially harmful polypharmacy is very common in older people living in aged care facilities. To date, there have been no double-blind randomised controlled studies of deprescribing multiple medications.

Methods

three-arm (open intervention, blinded intervention and blinded control) randomised controlled trial enrolling people aged over 65 years (n = 303, noting pre-specified recruitment target of n = 954) living in residential aged care facilities. The blinded groups had medications targeted for deprescribing encapsulated while the medicines were deprescribed (blind intervention) or continued (blind control). A third open intervention arm had unblinded deprescribing of targeted medications.

Results

participants were 76% female with mean age 85.0 ± 7.5 years. Deprescribing was associated with a significant reduction in the total number of medicines used per participant over 12 months in both intervention groups (blind intervention group −2.7 medicines, 95% CI −3.5, −1.9, and open intervention group −2.3 medicines; 95% CI −3.1, −1.4) compared with the control group (−0.3, 95% CI −1.0, 0.4, P = 0.053). Deprescribing regular medicines was not associated with any significant increase in the number of ‘when required’ medicines administered. There were no significant differences in mortality in the blind intervention group (HR 0.93, 95% CI 0.50, 1.73, P = 0.83) or the open intervention group (HR 1.47, 95% CI 0.83, 2.61, P = 0.19) compared to the control group.

Conclusions

deprescribing of two to three medicines per person was achieved with protocol-based deprescribing during this study. Pre-specified recruitment targets were not met, so the impact of deprescribing on survival and other clinical outcomes remains uncertain.
Distribution of multiunit pitch responses recorded intracranially from human auditory cortex
Authors: Berger Joel I , Gander Phillip E , Kikuchi Yukiko , Petkov Christopher I , Kumar Sukhbinder , Kovach Christopher , Oya Hiroyuki , Kawasaki Hiroto , Howard Matthew A , Griffiths Timothy D
Published: May 2023

The perception of pitch is a fundamental percept, which is mediated by the auditory system, requiring the abstraction of stimulus properties related to the spectro-temporal structure of sound. Despite its importance, there is still debate as to the precise areas responsible for its encoding, which may be due to species differences or differences in the recording measures and choices of stimuli used in previous studies. Moreover, it was unknown whether the human brain contains pitch neurons and how distributed such neurons might be. Here, we present the first study to measure multiunit neural activity in response to pitch stimuli in the auditory cortex of intracranially implanted humans. The stimulus sets were regular-interval noise with a pitch strength that is related to the temporal regularity and a pitch value determined by the repetition rate and harmonic complexes. Specifically, we demonstrate reliable responses to these different pitch-inducing paradigms that are distributed throughout Heschl’s gyrus, rather than being localized to a particular region, and this finding was evident regardless of the stimulus presented. These data provide a bridge across animal and human studies and aid our understanding of the processing of a critical percept associated with acoustic stimuli.
Artistic, Artworld, and Aesthetic Disobedience
Authors: Burgos Adam , Lintott Sheila
Published: May 2023

Jonathan Neufeld proposes a concept of aesthetic disobedience that parallels the political concept of civil disobedience articulated by John Rawls in A Theory of Justice. The artistic transgressions he calls aesthetic disobedience are distinctive in being public and deliberative in their aim to bring about specific changes in accepted artworld norms. We argue that Neufeld has offered us valuable insight into the dynamic and potent nature of art and the artworld; however, we contend that Neufeld errs by constraining aesthetic disobedience to the artworld. Through a reconsideration of the parallel between aesthetic and civil disobedience, we illustrate how aesthetic disobedience is more accurately conceived of in terms of two kinds of acts: artistic and artworld. In addition to artistic disobedience and artworld disobedience, we add a broader and more diverse sort of transgressive aesthetic disobedience. Our aim is to articulate how Neufeld’s account of a kind of disobedience in the artworld that parallels civil disobedience can prove even more generative.