bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of public debt as a moderator in the relationship between revenues and capital expenditures of the Jordanian government
Authors: Ali Al Hayek Mohammad
Published: July 2024

This study aims to investigate the relationship between government revenue and capital expenditures in Jordan from 2003 to 2022, with public debt as the moderating variable. Utilizing data from the Jordanian Ministry of Finance’s final accounts and the Central Bank of Jordan’s reports, the study employed regression analysis techniques in the statistical software E-Views to test the study’s hypotheses. The findings reveal a positive relationship between revenue and capital expenditures, indicating the significance of revenue in determining the level of capital expenditures. Additionally, a positive relationship is observed between public debt and the magnitude of capital expenditures, suggesting that a portion of capital expenditures is covered by government revenues while the remaining portion is financed by public debt. Upon introducing the moderating variable (public debt) into the analysis, the impact of public debt on the relationship between revenue and capital expenditures becomes evident, indicating that public debt strengthens the relationship between revenue and capital expenditures. In light of the study’s findings, the government should focus on enhancing and increasing revenue and financing sources while rationalizing expenditures. Moreover, it should strive to improve its services and infrastructure to attract more investments and reduce public debt.
Association between Interleukin-6 and Multiple Acute Infarctions in Symptomatic Intracranial Atherosclerotic Disease
Authors: Mo Jinglin , Chen Zimo , Wang Mengxing , Cheng Aichun , Li Jiejie , Pan Yuesong , Jiang Yong , Jing Jing , Wang Yongjun , Pu Yuehua , Li Zixiao
Published: July 2024

Background:

Interleukin-6 (IL-6) plays an important role in the pathophysiology of
atherosclerosis. This study aimed to determine whether IL-6 is a crucial biomarker associated with
Multiple Acute Infarctions (MAIs), which indicate an important stroke mechanism of artery--
to-artery embolism with a high risk of stroke recurrence in symptomatic Intracranial Atherosclerotic
Disease (sICAD). We tested the association between circulating IL-6 levels and the presence of
MAIs in a prospective population-based registry.

Methods:

We included 1,919 patients with sICAD and baseline IL-6 levels from the Third China
National Stroke Registry for the current analysis, The baseline IL-6 was centrally measured at Beijing
Tiantan Hospital, Images of the brain parenchyma and vascular structures were digitized and
then blindly and independently read by two groups of trained readers, The recruited patients were
divided into 3 groups according to IL-6 tertiles, The relationship between baseline IL-6 tertile levels
and the presence of MAIs was modeled using multivariate logistic regression.

Results:

Compared to patients in the first IL-6 tertile those in the second and third tertiles demonstrated
a significantly higher proportion of MAIs. The odds ratios were 1.81 [95% Confidence Interval
(CI), 1.42-2.30] for the second versus first tertile and 2.15 (95% CI 1.66-2.79) for the third versus
first tertile, The proportion of patients with MAIs increased with rising IL-6 tertiles observed
at 59.3%, 71.6% and 76.4% for the first, second and third tertiles, respectively (P for trend <
0.001). The association between higher IL-6 tertiles and increased proportion of MAIs was also
present in subgroups defined by age < 65 years, age ≥ 65 years, male, and high-sensitivity C-reactive
Protein (hs-CRP) ≥ 2 mg/L. Furthermore, a significant interaction was detected for the hs-
CRP subgroup (P = 0.038). In sensitivity analyses, the positive correlation between IL-6 levels
and the proportion of MAIs remained consistent.

Conclusion:

In patients with sICAD, higher IL-6 levels were associated with an increased proportion
of MAIs. IL-6 could be used as a biomarker and a potential therapeutic target for future
atherosclerosis treatment and prevention in patients with sICAD.
Unraveling the Anti-Obesity Potential of Luteolin: Mechanistic Insights
Authors: Sharma Akhil , Kaur Gagandeep , Kaur Amandeep , Devi Sushma
Published: July 2024

Luteolin, a flavonoid, has gained attention for its anti-obesity benefits. Luteolin has
been shown to regulate multiple aspects of adipose tissue biology, including adipocyte differentiation
and adipokine secretion. It prevents the formation of adipocytes by interfering with the expression
of important transcription factors, such as PPAR-γ and C/EBP-β. Furthermore, luteolin possesses
anti-inflammatory properties, inhibiting the production of pro-inflammatory adipokines,
such as TNF-α and IL-6. These actions help to reduce the persistent low-grade inflammation associated
with obesity, which eventually improves metabolic health. It increases the production of
adiponectin, an adipokine with anti-inflammatory and antioxidant properties. This change in the
adipokine level may result in metabolic benefits in obese persons. Additionally, the antioxidant activities
of luteolin shield adipocytes from oxidative stress, preserving their function and contributing
to overall metabolic equilibrium. This study provides scientific evidence supporting luteolin as
an anti-obesity agent in depth, focusing on its mechanisms of action, experimental studies, pharmaceutical
formulation studies, and other reported clinical evidence.
Microwave Thermal Ablation of Thyroid Nodules with the MONTREAL
Technique: Preliminary Clinical Results
Authors: Mazzucco Mauro , Mattarello Mee Jung , De Santi Francesca , Peron Cinzia , Mazzucco Anna , Terni Tommaso , Tosoratti Nevio
Published: July 2024

Ultrasound-guided percutaneous Microwave Thermoablation (MWA) is an increasingly
popular minimally invasive therapy for the treatment of benign thyroid nodules due to its
remarkable heating velocity and resilience to heat sinking. We present a cohort of 26 patients
(17 F, 9M, mean age 56.2yy) with 20 goiters (mean volume 34.9cc, min 6.5cc-max 84cc) and 6
autonomously functioning nodules (AFTNs, mean volume 11.6cc, min 3.5cc-max 24cc) treated
with MWA, using the moving shot technique and a novel energy delivery algorithm
(MONTREAL), based on intra-operative real-time reflectivity measurements: each moving shot
was automatically terminated when reflectivity was observed to ramp up. 17G or 18G internally
cooled 2.45 GHz applicators were used (AMICA-PROBE, HS HOSPITAL SERVICE SpA),
operated at 15-30W. On average, each treatment deposited 9.9±5.5kJ during 696±325s, through
26.7±14.4 moving shots: the mean moving shot duration was 28.1±9.0s, yielding a mean ablation
time per unit nodule volume of 34.3±19.1s/cc. No mild nor severe complications were recorded.
Post-MWA ultrasound follow-up showed a mean volume reduction ratio of 59.1±10.2%
[min 44% – max 80%] at 3 months and of 70.1±8.5% [min 53% – max 91%] at 6 months, with
slightly better outcomes in the AFTNs sub-group (volume reduction of 65.3±10.2%/76.0±4.0%
at 3/6 months and, in all cases, normal TSH values at 3 months upon pharmacological therapy
suspension). MWA treatments of benign nodules with the MONTREAL technique appeared to
be safe, fast, and effective. Further research is warranted to confirm these preliminary results.
Fabrication and Characterization of Andrographolide-loaded Microsponges to Enhance Oral Bioavailability of Drug against Colon Cancer Using HT29 Cells
Authors: Archana  , Deshmukh Rohitas
Published: July 2024

Background:

The current research aimed to determine ways to improve the bioavailability
of andrographolide (AGP) for use in colon cancer treatment by developing and evaluating microsponges
loaded with the drug.

Methods:

Utilising the quasi-emulsion solvent diffusion approach, microsponges containing AGP
were synthesised. A total of ten formulations were prepared using different concentrations of drug,
polymer and other excipients. Particle size, shape, and differential scanning calorimetry (DSC) were
used to characterise the microsponges that were created. To find out the rate at which the microsponges
would expel their contents, researchers measured their release dynamics. In vitro anticancer
activity of formulation was determined using HT29 cells

Results:

Results showed that the percentage yield of the formulations ranged from 10.85-41.03%.
The highest drug concentration was achieved in formulation F8 with a particle size of 33.7 nm. SEM
analysis demonstrated that the particles were round and possessed a rough and porous surface. Increasing
the ratio of ethyl cellulose to AGP reduces surface roughness. The microsponge's DSC
difractogram reveals prominent peaks at 18°, 24°, and 38° (2 θ) with reduced intensity, suggesting
that the microsponges' crystalline character has diminished. In vitro drug release study showed
93.85% release upto 12 hours. Mathematical models showed normal release of the formulations with
“n” values greater than 0.90 of all the formulations. Formulation F8 decreased the HT-29 cells' ability
to survive. The percentage of cell cytotoxicity was 75.54 at 100μg/ml. Since AGP microsponges
had a detrimental effect on the survival of colorectal cancer cells.

Conclusion:

It can be concluded from the study that prepared formulations possess anticancer properties
against cancerous cells and can be used as an alternative anticancer drug.
Effect of 17β-Estradiol on Endothelial Cell Expression of Inflammation- Related MicroRNA
Authors: Levy Ma’ayan V. , Fandl Hannah K. , Hijmans Jamie G. , Stockelman Kelly A. , Ruzzene Samuel T. , Reiakvam Whitney R. , Goldthwaite Zoe A. , Greiner Jared J. , DeSouza Christopher A. , Garcia Vinicius P.
Published: July 2024

Background:

Estrogen plays a protective role in vascular health due, in part, to its
regulation of endothelial inflammation. However, the mechanism(s) by which estrogen negatively
regulates inflammatory signaling pathways is not completely understood. MicroRNAs (miRNAs)
are recognized as sensitive and selective regulators of cardiovascular function, inflammation, and
disease, yet the effects of 17β-estradiol on the endothelial miRNA profile are largely unknown.

Objective:

The aim of this study was to determine the effect of 17β-estradiol on the expression of
inflammation-associated miRNAs in endothelial cells in vitro.

Methods:

Human Umbilical Vein Endothelial cells (HUVECs) were treated with media in the
absence (control) and presence of 17β-estradiol (100 nM) for 24 hr. Thereafter, endothelial cell
release of cytokines (IL-6 and IL-8), the intracellular expression of the central protein inflammatory
mediator NF-κB, and the levels of inflammatory-associated miRNAs: miR-126, miR-146a,
miR-181b, miR-204, and miR-Let-7a, were determined.

Results:

17β-estradiol-treated cells released significantly lower levels of IL-6 (47.6±1.5 pg/mL
vs. 59.3±4.9 pg/mL) and IL-8 (36.3±2.3 pg/mL vs. 44.0±2.0 pg/mL). Cellular expression of total
NF-κB (26.0±2.8 AU vs. 21.2±3.1 AU) was not different between groups; however, activated
NF-κB (Ser536) (12.9±1.7 AU vs. 20.2±2.2 AU) was markedly reduced in 17β-estradiol-treated
cells as compared to untreated cells. Furthermore, cellular expressions of miR-126 (1.8±0.3 fold),
miR-146a (1.7±0.3 fold), miR-181b (2.1±0.4 fold), miR-204 (1.9±0.4 fold), and miR-Let-7a
(1.8±0.3 fold) were markedly increased in response to 17β-estradiol treatment.

Conclusion:

These data suggest that the anti-inflammatory effect of 17β-estradiol in endothelial
cells may be mediated by miRNAs.
Exploring the Filling Related Defect in Vertical Centrifugal Castings for A413 and A356 Using 3D Transient Simulation
Authors: Mazloum Kamar , Al Njjar Ameen , Sata Amit
Published: July 2024

Background:

Defects in casting related to the stage of the process, like filling or solidification
and related to many parameters (process, geometric, and material). In the casting field, extreme
temperatures refer to the high heat necessary to melt and maintain metals or other materials
in a liquid state, enabling them to be shaped into desired forms using molds. Extreme temperature
and other factors, such as die rotation speed play an important role in the formation of defects, as
their significant increase leads to excessive viscosity or instability in the flowing metal. The effective
method that takes the least time and cost to explore this defect is simulation.

Objective:

This study aims to predict the porosity defect for the 3D pattern in vertical centrifugal
casting during filling of A413 and A356.

Methods:

A three-dimensional transient simulation was done for flowing mode in five molds having
various aspects ratio from 1 to 2 in step 0.25 with change in pouring temperature and mold rotation
speed (700 − 800 °c and 50 − 150rpm with step 25 °c , 25 rpm) considering the existance
of air phase with fluid inside the mold.

Results:

The study's findings reveal that when the pouring temperature exceeds 750°C and the mold
rotation speed surpasses 100 RPM, porosity significantly decreases. Generally, increasing the rotation
speed from 50 to 150 RPM reduces defects, except when the pouring temperature is low, specifically
less than 725°C. Additionally, porosity decreases with an increase in the aspect ratio up to
2, accompanied by the lowest interface heat transfer coefficients observed at 6867.62 W/(m^2·K)
for A413 and 7703.89 W/(m^2·K) for A356.

Conclusion:

Determining the interface’s heat transfer coefficient at each moment ensures accuracy
and reliability in the obtained results. By following these simulations for any alloy, the quality of
the castings can be improved.
Emerging Applications of Herbal-Based Nanocosmeceuticals for Beauty and Skin Therapy
Authors: Shree Dipthi , Patra Chinam Niranjan , Sahoo Biswa Mohan
Published: July 2024

:

Herbal cosmeceuticals are a rapidly expanding sector of the personal care industry,
and their use has greatly expanded over time. The advancement of research and development is
demonstrated by nanotechnology, which boosts product efficacy by delivering innovative solutions.
The application of nanotechnology is growing in the field of cosmeceuticals to address
numerous shortcomings of conventional herbal products. Lower penetration and high compound
instability of various cosmetic products for prolonged and enhanced compound delivery to
beauty-based skin therapy are the main problems with the use of phyto-based cosmeceuticals.
Nanosized delivery technologies are currently being used in cosmeceutical industries and products
for prolonged and improved delivery of phyto-derived bioactive chemicals to solve these
drawbacks. The aseptic sensation of many cosmeceutical products is improved by nanosizing
phytocompounds, which also improve skin-protective properties and sustained delivery. Nanocosmeceuticals
are now commonly utilized on skin, hair, lips, and nails to treat disorders including
wrinkles, photoaging, hyperpigmentations, dandruff, hair damage, chapped lips, etc. Some of
the cutting-edge nanotechnologies now being used for improved delivery of the phytoconstituents
in skin care therapy include liposomes, ethosomes, glycerosomes, transferosomes, niosomes,
phytosomes, nanostructured lipid carriers, solid lipid nanoparticles, polymeric nanoparticles,
nanoemulsions, nanogels, etc. The advantages of these novel nanocarriers include improved skin
penetration, controlled and prolonged drug release, increased stability, site-specific targeting,
high entrapment efficiency, and improved bioavailability. Several phytoconstituents such as curcumin,
aloe vera, resveratrol, lycopene, tocopherol, quercetin, catechins, and lutein have been
successfully nanosized by employing various delivery technologies and incorporated in various
gels, lotions, and creams for skin, lip, hair, and nail care for their sustained effects. The present
article primarily focuses on the use of phytocompounds in various cosmeceutical products, diverse
classes of innovative nanocarriers employed for delivering herbal nanocosmeceuticals, and
the use of various phytobioactive compounds in novel nanocosmeceutical formulations to improve
skin-based therapy.
A Comparative Study of Dexamethasone and Methylprednisolone in COVID-19 Patients: Clinical Outcomes and Inflammatory Markers
Authors: Moghaddam Alireza Ziaei , Soleimani Mostafa , Imani Behnam , Hejazi Sepide , Taherynejad Mohammadhossein , Kabiri Mona , Emadzadeh Maryam , Ravanshad Sahar
Published: July 2024

Background:

The Coronavirus disease 2019 (COVID-19) pandemic, prompted by
SARS-CoV-2, has created complicated health crises. An excessive inflammatory response and cytokine
storm characterize severe COVID-19. Corticosteroids like dexamethasone and methylprednisolone
are used for their anti-inflammatory effects, but comparisons of their efficacy are lacking.

Objective:

This study seeks to rigorously assess and contrast the effectiveness of dexamethasone
and methylprednisolone in combating COVID-19 infections.

Methods:

This retrospective clinical study evaluates the effects of these two corticosteroids by reviewing
the files of 500 hospitalized COVID-19 patients. The baseline characteristics of the patients,
chest CT severity score, type of steroid prescription, duration of hospitalization and steroid
prescription, dosage of corticosteroid therapy, their recovery status, hospital mortality, and specific
disease severity-associated markers, such as lactate dehydrogenase (LDH), complete blood
count (CBC), C-reactive protein (CRP), and Erythrocyte sedimentation rate (ESR) were collected
and compared.

Results:

The study found no significant difference in most disease severity-associated markers between
the two corticosteroid groups. However, lower mortality rates and shortened hospital stays
were significantly associated with dexamethasone, especially in critical patient groups. A detailed
analysis of inflammatory markers suggested minimal differences based on the type of corticosteroid
used.

Conclusion:

The study indicates that dexamethasone may have some advantages in specific clinical
outcomes. Further research needs to explore the mechanisms involved despite similar anti-inflammatory
profiles.
Decoding Acne Vulgaris: Insights into Pathogenesis, Treatment Modalities, Diagnosis and Recent Advancements
Authors: Guleria Priyanka , Joshi Shiana , Parmar Shivika , Sharma Tarun , Chaudhary Archana , Kumar Pravin , Ashawat Mahendra Singh
Published: July 2024

Background:

Acne vulgaris, an alternative term for acne, is a persistent inflammatory
skin condition affecting the pilosebaceous unit. Its development involves a combination of factors,
including increased sebum production, changes in keratinization leading to comedone formation,
colonization of hair follicles by Propionibacterium acnes (P. acnes), and the release of inflammatory
mediators in the vicinity of the pilosebaceous unit.

Objective:

This review provides a concise overview of acne, covering its pathogenesis, epidemiology,
diagnosis, treatment options, and recent advancements involved in acne.

Discussion:

Various therapeutic approaches, encompassing topical, systemic, combination, and
hormonal treatments, are employed to address acne. Prolonged use of synthetic medications is
common in acne therapy, but their potential for severe side effects prompts a preference for herbal-
based treatments. Herbal remedies utilizing extracts of natural origin are considered safer due
to their lower toxicity and reduced likelihood of adverse drug reactions. Recent advancements, particularly
in personalized medicine and microbiome research have enhanced our understanding and
opened new avenues for more effective management.

Conclusion:

Decoding acne vulgaris has provided insights into its pathogenesis, treatment modalities,
diagnostics, and recent advancements. Integrating synthetic and herbal treatments, personalized
medicine, microbiome research, and advanced modeling techniques offer promising acne management
strategies.
TED Talks: análise da estrutura retórica do género sob a perspetiva da teoria de movimentos
Authors: Isrigova Victoria
Published: July 2024

This article explores the rhetorical structure of TED Talks, a popular form of online discourse, through a theoretical framework based on Swales' move analysis. Drawing on previous studies and employing a corpus study approach, the article investigates the main moves and rhetori-cal steps within TED Talks, focusing on their communicative purposes. The results reveal a non-linear organization of rhetorical elements, reflecting the oral nature and adaptability of the genre. It is noteworthy that elements such as audience orientation and speaker presentation show flexibility in their arrangement, emphasizing the speaker's authority and engagement. The recurrent use of exemplification emerges as a significant rhetorical strategy, facilitating the audience's understand-ing of complex concepts. The study also raises questions about the genre's independence, rhetori-cal consistency across scientific domains, and communicative goals, suggesting avenues for further research.
A emergência da mulher nas carreiras policiais como acontecimento: entre os já ditos machistas e os confrontos discursivos nas mídias digitais
Authors: Santana Cremilton de Souza , Cortes Gerenice Ribeiro de Oliveira
Published: July 2024

This study aims to investigate the emergence of women in police careers and the Brazilian Navy as a discursive event and the effects of this dynamic in digital media networks. For this, we are anchored in the theoretical assumptions of Discourse Analysis (DA) from a Pêcheux perspective. For the analytical movements, we constructed a discursive corpus with three discursive sequences (DS) from a digital materialities archive: one collected from the social network Facebook, one from the website Defesa em Foco, and another from the São Paulo State Legislative As-sembly website. Data collection was performed using the Lightshot screenshot application. The re-sults show that although machismo ideological discourses still intersect, under the play of memory forces, the emergence of women in police roles in Brazil is configured as a discursive event. This is because it instigates disruption and deregulation of the machismo and military discourse memory, as women police officers begin to occupy a space previously reserved only for men. Furthermore, by occupying the space of social and digital networks, women police officers gain visibility with a subject-position of resistance to machismo discourse
A nutritive review on Shaka Varga in Charaka Samhita
Authors: Premlata  , Bhuwal Ram  , Rajendra Prasad Purvia
Published: July 2024

The vegetables are described under Shaka Varga in Ayurvedic classical books. Caraka Samhita is the most important repository of Ayurveda classics. In Caraka Samhita, Shaka Varga mentioned under the classification of diet (Food). The Shaka Varga includes Patra Shaka (Green Leafy Vegetables), Kanda Shaka (Rhizome Vegetables), Kaanda Shaka (Stem Vegetables), Pushpa Shaka (Flower Vegetables), Phala Shaka (Fruit Vegetables) etc. Vegetables are also supply vitamins and minerals to the diet and are sources of phytochemicals that function as antioxidants, phytoestrogens, and anti-inflammatory agents. The consumption of these vegetables may play a role in preventing human diseases in which free radicals are involved such as cancer, ageing, cardiovascular diseases. In this review, we describe the existing literature available in Caraka Samhita on Shaka Varga (vegetables). We also review to identify the plants with their botanical identification, properties, therapeutic indications, and chemical constituents. There are some plants in this review study whose botanical identification has not been found.
A Review of Nagkeshar churna management in bleeding piles
Authors: Priyanka Priya  , Deepali Sundari Verma
Published: July 2024

Because of changing in lifestyle of modern society, haemorrhoid leading one of biggest challenging disease nowadays, it has high prevalence and low morbidity. It affect the high-quality of life when it comes to internal haemorrhoid with extreme bleeding the affected person turn out to be integral day by way of day with addition of other symptom associated to blood loss, so at once administration of this nation of affairs, but all of these are expensive, time ingesting ,painful ,have most postoperative complication, and the recurrence cost is moreover high, so we can consider the treatment principle given by Acharya Susuruta, for the management of Arsha, Bhesaj Karma is one among them. Bheshaja Chikitsa is a first line of treatment in various diseases. It is viewed to be a conservative line of remedy useful to cure and stop the recurrence of ailments. According to Indian Herbal System (Ayurveda), Nagkeshar is considered one of the most important herb used widely in bleeding disorders. The Nagkeshar improves digestion and appetite, used in fever, vomiting, nausea, excessive thirst, bad breath, pile, excessive sweating, Skin diseases like herpes, infertility etc.
A review on disease Nadi Vrana
Authors: Megha R  , Ranjith Kumar
Published: July 2024

Nadi-Vrana is a tubular structure which contains pus within it or Nadi-Vrana is a blind tract which has continuous pus discharge from it. According to various Acharyas, if Vranashopha is not timely drained or treated during its Pakvaavastha or neglected at this stage, it traverses into deeper tissues and results in formation of Nadi-Vrana. The disease nature of the Nadi-Vrana can be correlated to Sinuses of the contemporary science, where Sinus is the epithelial lined tubular structures which contain unhealthy granulation tissue. Acharyas have given detailed explanation on different types of Nadi-Vrana along with its treatments, which include Bhaishajya Chikitsa, Kshara Sutra application, Agnikarma and Shastrakarma. Among these various treatment modalities Kshara Sutra application stands out in present days in combating the disease Nadi-Vrana. Shalyaja/Agantuja Nadi-Vrana can be correlated to Pilonidal sinus by its causative factors and clinical features. In this article the compiled explanation of Nadi-Vrana which includes its causes, classification, signs and symptoms, management and many more descriptions according to Ayurveda and modern medicine will be dealt.
Psychological disorder w.s.r. to Daivavyapashraya Chikitsa (Mantra Chikitsa)
Authors: Bharati N. Deshmukh  , Brijesh R. Mishra
Published: July 2024

Introduction: The perfect balance of mind, body and soul is considered as complete health in Ayurveda. Ayurvedic theory of mental health is based on combination of Triguna, Tridosha, and Panchmahabhuta. The dynamic balance of these above elements creates a good mental health. Balanced dosha of mind regulates the emotion while disturbed Dosha of mind plays an important role in the pathogenesis of mental diseases. In Ayurveda many references of Mana and treatment of Manas Vikara are available, which would be easy to understand and rewarding the field of treatment. These treatment has been categorised into 3 types i.e., Daivavyapashraya, Yuktivyapashraya and Satvavajaya. Daivavyapashraya Chikitsa is one of the treatment approaches concerned with spiritual way of treatment. Objectives: 1) To review literature related to the concept of Daivavyapshraya Chikitsa. 2) To find out details about Mantra Chikitsa which is used in Psychological Disorders. Materials and Methods: Ayurveda texts, Ayurvedic Samhitas, published articles are the materials for review of compilation and analysis of the concept. Discussion and Conclusion: Daivavyapashraya Chikitsa is considered Ashukari and cures the disease without any difficulties. It act as a Vyadhihar because of Daiva Prabhava. Mantra Chikitsa is one of the different modalities of Daivavyapashraya Chikitsa. Mantra has been explained in both Swastha and Atura in the classics. In the present paper literature regarding the utility and importance of Mantra Chikitsa in psychological disorder has been explained.
A review on Ulat Kambal (Abroma augusta Linn.)
Authors: Ashwarya  , Rosy Gupta
Published: July 2024

Plants are boon to mankind. They have been used to support life in all ways. Many drugs are also of plant origin. Research and exploration are ever going to unlock their potential benefits. The plant Ulat Kambal (Abroma augusta L.) or Devil’s cotton belonging to family Malvaceae, is generally found in hotter parts globally. Not much mentioned in Ayurveda text, fresh juice from its root bark is reported to be useful in congestive and neuralgic forms of dysmenorrhea, amenorrhea in recent times only. The broad range of therapeutic potential of this plant includes gonorrhoea, bronchitis, bronchopneumonia, abscess, sores etc. Also, the leaves are found to be beneficial in diabetes, rheumatic pain and sinusitis. General overview along with pharmacological and pharmacognostical aspect of Ulat Kambal (Abroma augusta L.) are tried to be explored through this review article.
Ayurvedic treatment of Psoriasis (Ekakustha) through Shaman therapy : Case Study
Authors: Tapaswini Dalasinghray  , Ajay Ku Sahu  , Bharat Kumar Padhar  , Pooja Lekhak  , Satya Santosh Sahoo
Published: July 2024

This case study highlights the successful management of psoriasis (Ekakustha) through Ayurvedic Shaman Chikitsa in a 30-year-old male patient with dry, scaly lesions on the scalp and extensors. The patient, unresponsive to allopathic treatment, exhibited dietary indiscretions and irregular bowel habits. Ayurvedic treatment involved Shamana Chikitsa, incorporating Panchanimba Churna, Kaishor Guggulu, Khadirarista and Psoria oil, alongside dietary modifications. Over four months, the patient experienced progressive improvement in itching, erythema and scaling, leading to a significant reduction in the Psoriasis Area and Severity Index (PASI) score from 22.1 to 0.6 which is near remission. This case underscores the efficacy of Ayurvedic Shaman therapy and the importance of personalized treatment strategies guided by classical Ayurvedic principles in managing psoriasis.
An experimental evaluation of Anti-Inflammatory and Analgesic Activity of Allium Cepa Linn. and Allium Ascalonicum Linn. - A comparative study
Authors: Aby Mathew Jose  , Akhila Vinod
Published: July 2024

Introduction: The drugs possessing Vataghna property are much indicated in classics for managing Shotha and Vedana. Cost-effective, widely available, and potent drugs should be encouraged over costly ones. The present study was undertaken based on this, focusing on the bulb of Allium cepa Linn. & Allium ascalonicum Linn. to evaluate the anti-inflammatory and analgesic activities employing carrageenan induced paw oedema in wistar albino rats and hotplate tests in mice, respectively. Materials and Methods: Fresh juice of Allium cepa Linn. and Allium ascaloncum Linn. was given to rats and mice orally to observe anti-inflammatory and analgesic activity, and observed for a day. Anti-inflammatory activity was evaluated using carrageenan induced paw edema model in wistar albino rats. Analgesic activity was evaluated using Hot plate method in mice. Experimental animals were divided into 4 groups, Group A as control was given distilled water and; Group B with standard drug, Paracetamol suspension, Group T 1 as test drug 1 with Swarasa of Allium cepa Linn; and Group T 2 as test drug II with Swarasa of Allium ascalonicum Linn. as per the calculated doses respectively. Results: Animals treated with the test drugs showed a significant reduction in paw oedema and had analgesic effects compared to the control group. The result obtained was also assessed by a one-way-ANOVA test. Discussion: The experiment concludes that both the test drugs have anti-inflammatory and analgesic capabilities. However, anti-inflammatory and analgesic effect was seen better in Allium ascalonicum Linn. than Allium cepa Linn. No adverse effects were noted in the study.
Ritmos de resistencia: la danza como voz en Comuna 23
Authors: Rubiano Elkin
Published: July 2024

El artículo analiza Comuna 23, una obra coreográfica del Movimiento en Colectivo (mec), destacando su importancia en la representación y transformación social a través del arte. La pieza utiliza la danza como medio para explorar y expresar las vivencias y desafíos de una localidad imaginaria que simboliza la realidad social y cultural de Cali. Se enfoca en cómo la danza, entrelazada con temas de identidad y resistencia, se convierte en un lenguaje poderoso para la expresión y el cambio social. La obra es un reflejo de la vida urbana en Cali, revelando las tensiones y esperanzas de sus habitantes. La danza, como acto de rebeldía y deriva, permite a los bailarines y al público conectar con experiencias personales y colectivas, desafiando las estructuras sociales existentes. El análisis destaca la relevancia de Comuna 23 en el contexto cultural caleño y su contribución a la discusión sobre la función del arte en la sociedad.
Concepción de los derechos de autor relativos a la música: análisis desde su fundamentación
Authors: Jaimes Melgarejo María Fernanda , Lozano Parra Johan Sebastian , Caballero Palomino Sergio Andrés , Morantes Franco Carlos Fernando
Published: July 2024

Introducción: El presente artículo de investigación aborda la temática de los derechos de autor en la industria musical por medio de la conceptualización de diversas nociones que componen los espectros de los derechos de propiedad intelectual. Objetivo: analizar a nivel doctrinal y jurídico el papel que tienen los derechos de autor y los derechos conexos dentro dela producción de una obra musical. Metodología: de tipo descriptivo y explicativo, cuya base es esencialmente cualitativa para lo referente a la forma de recolección y análisis de la información. Resultados: Tal estudio, permitió identificar como resultado una serie de parámetros que la música como elemento artístico tiene dentro del campo no solo de los derechos de autor, sino también desde una perspectiva meramente penal, en la que se identifica como a partir de la creación de una armonía o incluso un ritmo puede existir o detectarse el fenómeno del plagio. Conclusión: Se identificó que la música como producto del pensamiento humano, la misma al igual que cualquier otra actividad de la persona, posee una serie de derechos que van desde lo patrimonial, hasta lo moral por lo que están sujetos a protección jurídica.
Caminhando para uma Ciência Aberta: Uma abordagem estatística a partir da criação de resumos extrativos manuais e automáticos
Authors: Arias Arias Ivan , Oliveira Ramos de Castro Margarida
Published: July 2024

Nos dias de hoje, a difusão de novos meios facilitou a proliferação de dados científicos, que podem ser divulgados graças a novas técnicas de tratamento da informação. Visa-se, neste artigo, a partir do fluxo de trabalho que se estabelece entre dados abertos e ciência de dados, analisar resumos gerados de forma manual e de forma automática em termos estatísticos. Assim, avaliam-se novas possibilidades de tornar o conhecimento científico mais acessível ao caminharmos para uma democracia de dados. Desta forma, tomando um corpus de textos resumidos como ponto de partida, realizar-se-ão análises quantitativas com recurso a fundamentos teóricos que permitirão retirar conclusões relativamente à viabilidade da automatização para atingirmos uma ciência aberta.
Migração e Comunicação na América Central. Entrevista com Amparo Marroquín Parduci
Authors: Chaparro Manuel
Published: July 2024

Amparo Marroquín Parducci é professora do Departamento de Comunicação e Cultura da Universidad Centroamericana Simeón Cañas de El Salvador desde 1997. Há vinte anos, iniciou o estudo dos processos migratórios e a forma como estes influenciam a construção de identidades socioculturais (Marroquín Parducci & Huezo Mico, 2006). Abordou também as narrativas que os média constroem sobre esta questão (Marroquín Parducci & Carballo, 2021). O seu trabalho mais recente explora a constituição da profissão do coiote (guia) como o grande mediador dos riscos enfrentados pelos migrantes no seu caminho para um novo país. Foi professora visitante em países como Argentina, México, Colômbia, Equador, Espanha e EUA. Especialista na obra de Jesús Martín Barbero, é, desde 2021, decana da Faculdade de Ciências Sociais e Humanas da Universidad Centroamericana Simeón Cañas, em San Salvador.
Depresi sosial tokoh perempuan dalam kumpulan cerpen Jurig Paséa Jeung Nyi Karsih karya Tini Kartini (kajian sosiologi sastra Ian Watt)
Authors: Dewi Gita Kurnia , Koswara Dedi
Published: July 2024

This study aims to analyze and describe: 1) the social background of Tini Kartini as a representative of the community group, 2) the social situation of depression that occurred in the community when the work was published, 3) the content of the text of the Jurig Paséa jeung Nyi Karsih short story collection which reflects the idea of depression, and 4) a social mirror from Jurig Paséa jeung Nyi Karsih's short story collection. The method used in this research is descriptive method. The results of this study, firstly, Tini Kartini's social background as a representative of community groups, meaning how the author's social background is related to the publication of the literary work. Second, the depressed social situation that occurred in society when the work was published, clearly existed during the Soekarno era. Third, there are four ideas of depression that occur in female characters in the short story "Nyi Karsih". Fourth, the social mirror associated with the state of society. In conclusion, Jurig Paséa jeung Nyi Karsih's short story collection has a social depression of female characters with depressive ideas that influence them.
QUALITY MANAGEMENT CHALLENGES IN CONSTRUCTION PROJECTS: INVESTIGATING FACTORS, MEASURES, AND THE ROLE OF MATERIAL QUALITY CONTROL
Authors: Sin Chin Hon , Nee Ting Sim , Yong Lee Yee
Published: July 2024

In spite of the considerable advancements and enhancements that quality assurance and control have undergone in the construction industry, quality of the products remain an issue. Notable prevalence of poor quality in final products and facilities such as premature defects, repairs and reworks, and overall product failures within construction projects continue to affect both end users and project stakeholders. This study delved into the intricacies of the role of material as a contributor to poor construction quality, specifically in the context of building projects. Results showed that the utilisation of non-compliant and poor-quality materials during construction primarily stemmed from lack of quality assurance/quality control (QA/QC) activities and lack clarity in QA/QC process as prominent factors for poor quality construction material. In addition, the inability of the project supervisory team to identify, rectify by removing or replacing these poor-quality materials at critical work junctures is also a substantial contributory factor. The results underscore the necessity for an enhanced QA/QC framework that possesses the capacity to comprehensively identify, address, rectify, and if required, replace materials that fall short of the stipulated standards and regulations. By resolving the issues of utilisation of poor materials, it is hopeful that substantial improvements to the overarching quality issues of construction projects can be achieved.
TOWARDS DIGITAL FUTURE: UNLOCKING STRATEGIES TO INTEGRATE E-TENDERING IN THE CONSTRUCTION LANDSCAPE
Authors: Aziz Nur Mardhiyah
Published: July 2024

The advancement of technology has introduced the electronic tendering process commonly known as e-tendering, as a promising approach in the construction industry. Despite its potential benefits, the adoption of e-tendering remains limited in Malaysia. This article intends to reveal the reasons behind the poor adoption of e-tendering in view of integrating improvement in the construction procurement process. Suitable strategies for successful e-tendering adoption will be proposed to transform the Malaysian construction industry into a digital future. Semi-structured interviews were conducted with 15 experienced construction industry players, each with at least five years of experience using the e-tendering system. The snowball sampling technique was employed to identify suitable respondents. Data collected were analysed using thematic analysis, revealing six main groups of strategies: people, process, work environment, service provider, cost and technology. These proposed strategies can serve as a practical guideline for the construction industry players seeking to adopt e-tendering systems. Additionally, they offer valuable insights for construction companies and policymakers in planning, revising, and prioritising appropriate strategies and practices for the future development or upgrading of e-tendering systems within the construction landscape. This study significantly contributes to the knowledge on e-tendering adoption, particularly in Malaysia, and provides valuable support for researchers, construction industry players, and policymakers in their efforts to embrace a digital future in the construction sector.
GEOMETRICAL STUDY OF SUSTAINABLE POLYMER PILES WITH BUCKLING ANALYSIS
Authors: Lee Yee Yong , Ng Chee Khoon , Lee Yeong Huei , Ting Sim Nee , Kuan Hoo Tien Nicholas
Published: July 2024

Bakau piling is commonly used to support lightweight structures, such as drains, manholes, road, raft foundations and box culverts in construction, aside from its ability to sustain the deterioration of high-water table areas. Consequently, from the high demands, it is leading to mangrove deforestation. On the other hand, the alarming consent of environmental problems is that plastic products generated and becoming waste is increasing every year in Malaysia. Plastic products, mostly from polymer, require a long degradation period of about 1,000 years. Mangrove deforestation and the non-biodegradable nature of polymer waste have become environmental and global issues that leading to the innovative motive in this research by introducing polymer as a new material to the pile manufacturing, an alternative substitute for the bakau pile. This study aimed to optimise the polymer piles in relation to their structural behaviour under compressive stresses. Based on the developed numerical models, the optimum cross-sectional area of the polymer pile by using the buckling analysis is very much depending on the shape and size, specifically second moment of area and slenderness ratio. In preventing of torsional buckling, doubly symmetrical sections are the predominant consideration in the pile design. It found out that, the optimum polymer piles with 1.90 cm2 of cross-sectional area could be suggested for H shape pile, and the proposed material is the high-density polyethylene (HDPE) with virgin to recycle ratio of 50% (VR 50). While serving the environmental issues of mangroves and waste management, polymer pile is a feasible alternative for sustainable construction.
“US” VERSUS “THEM”: (RE)VISITING THE DAILY LIFE STRUGGLE OF STATELESS COMMUNITY IN SABAH, MALAYSIA
Authors: Tedong Peter Aning , Fazlie Fathin Amelina , Paul Devadason Evelyn Shyamala
Published: July 2024

The statelessness issue in Malaysia, particularly in Sabah state, began in the early 1970s due to the influx of Filipino refugees during the Mindanao insurgency and civil war. Scholars have documented that the stateless community in Sabah faces social discrimination and exploitation from various actors that cause them to live in vulnerability. Although previous research has written extensively about the plight of the stateless children in Sabah, there is limited research that talks about living conditions and the daily life struggles of the community itself. Therefore, using a qualitative approach, this study will explore the issues and challenges this community faces regarding their living conditions and access to essential services and amenities. In so doing, we conducted in-depth interviews with 30 stateless individuals living in Kota Kinabalu, Sabah. This study found that the stateless community in Sabah is having difficulty in terms of status registration, limited access to employment, worse housing and living condition, and no access to healthcare and education. Therefore, this study may improve the understanding of the state of statelessness in Sabah and provide input in constructing policy and mechanism frameworks to reduce the statelessness issue.
A CONCEPTUAL PAPER ON STIGMATISED DIMENSION TOWARDS RESIDENTIAL OVERHANG
Authors: Huri Norulelin , Ahmad @ Baharum Zarita , Hwa Ting Kien , Mohd Adnan Yasmin , Ishak Noor Farhana Akrisha
Published: July 2024

Property stigma refers to some characteristics, features, social values, or an event relating to land and buildings that can create a negative perception of a building, land, project, or neighbourhood area. It was identified as a significant factor contributing to the number of overhang residential units in Malaysia. This paper aims to develop a Conceptual Framework of a stigmatized dimension model for residential overhang properties that can assist the decision-making of the property market players (developers, planners, and property consultants). This study utilizes a desktop analysis that reviews previous scholars' conceptual frameworks. The conceptual paper develops four (4) stigma-related variables: Environmental stigma, phenomena stigma, neighbourhood stigma, and structural stigma. However, it is not an empirical investigation of property overhang since this paper needs to review in detail all the factors that influence the property overhang. The proposed conceptual framework will provide valuable insights into the stigmatized dimension of property overhang from the buyer's perspective. This paper provides an essential conceptual framework that will assist the property market players enhance their housing development and sales strategy, thereby increasing the bottom line. Subsequently, this will improve the property market efficiency and meet the demand and supply requirements.