bluuebunny/crossref_metadata_2025 huggingface dataset:
Jalisco a futuro 2012-2032. Construyendo el porvenir. Tomo 1. Informe ejecutivo, estudio de valores y protocolo de actualización
Authors:   Universidad de Guadalajara, Padilla López Raúl , Leal Moya Irma Leticia , Acosta Silva Adrián , Cortés Guardado Marco Antonio , Curiel Ballesteros Arturo , De León Arias Adrián , Escobar Latapí Agustín , Canales Cerón Alejandro Isidoro , Celis de la Rosa Alfredo de Jesús , Vargas Becerra Patricia Noemi , Silas Casillas Juan Carlos , Chavoya Peña María Luisa , De la Peña y Topete Guillermo Francisco Nicolas , Díaz Pérez Claudia del Carmen , Gómez López Alicia , Sánchez Bernal Antonio , Moloeznik Gruer Marcos Pablo , Zepeda Lecuona Guillermo Raúl , Bravo Padilla Itzcóatl Tonatiuh , Michel Velasco Jaime Enrique , Alonso Concheiro Antonio
Published: February 2025

Este informe ejecutivo de Jalisco a futuro 2012-2032 abunda en datos estadísticos y descripciones que muestran la realidad del estado. Como en los reportes amplios de los temas, aquí se compara aquello que se esperaba ocurriera con lo sucedido realmente en los pasados doce años; se comprendían los éxitos y fracasos, aciertos y errores, políticas certeras y fallidas; se identifican los escenarios positivos y negativos que Jalisco podría enfrentar desde ahora hasta el año 2032. Presenta los resultados esenciales de los once temas estudiados: naturaleza y medio ambiente, población y territorio, educación, economía, sociedad, salud y seguridad social, ciencia y tecnología, cultura, política y gobierno, administración y gestión pública, y seguridad pública y justicia.
Jalisco a futuro 2012-2032. Construyendo el porvenir. Tomo 4. Educación, cultura, ciencia y tecnología
Authors:   Universidad de Guadalajara, Acosta Silva Adrián , Silas Casillas Juan Carlos , Chavoya Peña María Luisa , De la Peña y Topete Guillermo Francisco Nicolas , Díaz Pérez Claudia del Carmen
Published: February 2025

Las áreas de educación, cultura, ciencia y tecnología deben conformar un fuerte entramado que conduzca al progreso económico y la satisfacción personal de los jaliscienses. En el ámbito educativo, conforme nos acercamos al nivel medio superior y superior, la cobertura es muy baja y desigual entre regiones. En el ámbito cultural, la promoción oficial predomina la visión elitista de la alta cultura, mientras que la ciencia y la tecnología parecen ajenas a la educación y la cultura de Jalisco. En todos los niveles educativos, las prácticas científicas y tecnológicas son vistas como actividades extrañas, exóticas, comprensibles sólo para iniciados, y de escasa utilidad cotidiana.
Análisis del impuesto al valor agregado en alimentos y la tasa al 0 % preferencial
Authors:   Universidad de Guadalajara/Jalisco/México, De la Garza Jiménez Eduardo Hector
Published: February 2025

En los últimos treinta años ha existido gran confusión en la aplicación del artículo 2-A, fracción I, incisos a) y b) de la Ley del Impuesto al Valor Agregado, en la que se establece la aplicación de la tasa preferencial del 0% del impuesto relativo, por lo que se ha reformado en más de 10 ocasiones generándose incontables litigios que han llegado al máximo tribunal del país. A la fecha, continúan generándose controversias en la materia, por lo que mediante la presente investigación se pretende conocer y analizar los antecedentes más relevantes emitidos por el poder legislativo, ejecutivo y judicial, para que los contribuyentes puedan conocer los alcances y limitaciones del artículo en cita, y en su caso opten por buscan conseguir resoluciones vinculantes respecto de su correcta aplicación en el caso concreto, a efecto de evitar contingencias fiscales.
Innovations in Strategic Finance and Accounting: Insights from Research Centers in a VUCA Environment
Authors: Wijaya Raden Muhammad Syah Arief Atmaja , Yuhertiana Indrawati , Sucahyati Diarany , Izaak Wilma Cordelia , Susilowati Endah , Suryaningrum Diah Hari , JASF Ignathia Martha Hendrati , Sukiswo Helmy Wahyu , Widodo Condro , Wati Seftin Fitri Ana , Fitri Anindo Saka
Published: February 2025

This paper examines the function of research centers in promoting strategic innovations in finance and accounting under the VUCA (Volatility, Uncertainty, Complexity, and Ambiguity) paradigm. This work employs a qualitative approach, incorporating benchmarking of research centers and literature evaluation, to identify approaches that improve financial resilience and adaptation. There are three research that develop financial resilience fields from Indonesia, Canada, and the United States that were analyzed. The data was obtained from field benchmarking and website observation. Comparative analysis is used to get a deep understanding of how research centers facilitate the advancement of innovative financial and accounting strategies to tackle challenges in VUCA environments. The results underscore the importance of collaboration, technological integration, and actionable frameworks, providing recommendations for academia, governments, and communities to connect research-driven innovation with practical application. This research highlights the unique role of research centers in addressing VUCA challenges by integrating technology-driven frameworks, data-centric tools, and community-based approaches, offering a comprehensive perspective on bridging theory and practice to enhance financial resilience and adaptability.
Pengaruh Green Accounting, Material Flow Cost Accounting, dan Environmental Performance terhadap Sustainable Development
Authors: Irene Kurnianingtyas  , Luh Putu Puji Trisnawati
Published: February 2025

This study aims to analyze the impact of green accounting, material flow cost accounting (production cost, area size, production output), and environmental performance on sustainable development. The population of this study includes energy sector companies in the subsectors of oil, gas, coal, and palm oil listed on the Indonesia Stock Exchange (IDX) during 2020-2022. Data were collected secondary through purposive sampling, resulting in 23 companies with 69 observations, based on certain criteria. The analysis methods include descriptive statistics, classical assumption tests (normality, multicollinearity, autocorrelation, and heteroscedasticity), multiple regression, coefficient of determination, and hypothesis tests t and F using Eviews. The results show that green accounting, production costs, and production output have an impact on sustainable development, while area size and environmental performance do not have an impact. This study is limited by the availability of data and the number of sample companies, as well as the subjective measurement of green accounting. It is recommended to expand the sample, use more objective measurements, and add variables such as green intellectual capital, environmental cost, and internal corporate governance strength for future research.
Improved techniques for exploration of groundwater deposits for conditions of rural areas of the Mangystau Peninsula
Authors: Biletskiy M. T , Ratov B. T , Khomenko V. L , Yesturliyev A. Ye , Makhitova Z. Sh
Published: February 2025

Purpose. Development of an innovative methodology for exploring groundwater deposits for the conditions of rural areas of the Mangystau Peninsula, which will allow finding sources of groundwater with acceptable mineralization with a minimum number of drilled wells.

Methodology. The assigned tasks were solved using a comprehensive research method, which includes a review and synthesis of literary sources; patent market research; study of geological and hydrogeological conditions of the work area; critical analysis of existing methods for exploration of groundwater deposits; studying and summarizing previously conducted exploration work in the area and developing recommendations for improving exploration methods.

Findings. The reasons for the insufficient use of groundwater reserves on the Mangystau Peninsula have been established. A highly effective method for exploring groundwater deposits has been developed, taking into account the specific features of the Mangystau Peninsula – vast sparsely populated areas and the chaotic location of aquifers with acceptable mineralization. Reducing the number of wells drilled is achieved by searching and identifying the boundaries of the aquifer using successive cycles with a moving center, which allows you to systematically explore the area and find the best aquifers.

Originality. For the first time, a methodology for exploring groundwater deposits has been proposed, the main provisions of which are as follows: exploration wells are drilled with a small diameter, and only wells that have uncovered horizons with acceptable mineralization are subject to expansion; wells are drilled using a combined grid, combining the capabilities of radial and regular grids; the centers of the first cycle of the exploration grid are existing water intakes containing water with acceptable mineralization; from such centers, drilling is carried out along a radial grid of six wells; when a horizon with acceptable mineralization is discovered, the discovered well becomes the center of the second cycle of a radial grid of six wells, at least three of which have already been drilled in the previous cycle. Further exploration continues with subsequent cycles with the goal of constructing wells with acceptable flow rate and mineralization.

Practical value. The implementation of the developed methodology is of great practical importance for the further development of oil and gas production, industrial production and agriculture of the Mangystau Peninsula, as well as social significance for meeting the needs of the growing population of the region for high-quality water for drinking and household water supply. The use of the developed methodology makes it possible to reduce the number of useless wells, minimizing exploration costs.
Well operation by plunger rod pumps in difficult conditions
Authors: Togasheva A , Bayamirova R , Ratov B , Sudakov A , Makyzhanova A
Published: February 2025

Purpose. Research and optimization of the processes of operation of wells equipped with plunger rod pumps in conditions with increased complexity, such as high oil viscosity, high pressure, aggressive geological and physical conditions and significant fluctuations in flow rate, in order to increase the efficiency and reliability of the plunger rod pump (UPSH) installation, increase well productivity and reduce operating costs.

Methodology. The authors used the following scientific methods: the method of analysis and synthesis – for a review and systematization of existing scientific publications and experiments on the operation of wells with UPR in conditions of increased complexity; the method of observation and data analysis – for an analysis of the operation of UPR in various conditions, including the study of the effectiveness of their work in difficult geological conditions; experimental methods – for conducting field experiments to evaluate the work of UPSH in conditions of increased complexity.

Findings. The use of inhibitors, tubing (tubing and compressor tubes) with protective coating, rod centralizers and special pumps is proposed to combat wiping and deposits in deep pumping equipment. Low-cost options are recommended for use in small and medium-sized wells up to 1,500 m deep, providing an efficiency of 50‒60 % with a viscosity of up to 200 MPaˑs and a sand content of up to 10 %.

Originality. The theory of the causes of the failure of the GNR and the downtime of the mechanized fund of production wells equipped with UPSH has been further developed. The influence of complicated conditions on the operational characteristics of plunger rod pumps has been established. The use of OPN in production wells at the Uzen field is justified, taking into account technical and economic factors in comparison with other methods of operation.

Practical value. The development and implementation of methods that increase the inter-repair period of wells at the Uzen field make it possible to reduce the cost of repair and preventive maintenance, increase the efficiency of operation and reliability of the mining complex, especially at a late stage of field development. As a result of the pilot tests conducted, the average duration of the inter-repair period of the mechanized fund in 2021 increased by 14 days compared to 2018.
Static continuous bulk material model for inclined bunker section
Authors: Radkevytch A. V , Bannikov D. O , Wu H , Cheng X
Published: February 2025

Purpose. Obtaining an analytical pattern of pressure distribution of bulk material based on the classical Jansen’s model for an inclined outlet part of a hopper with an arbitrary cross-sectional shape.

Methodology. The work used a set of research methods, including scientific analysis and synthesis of available technical information regarding the current regulatory and professional approaches to determining the pressure from bulk material in container structures. Computer modeling methods based on the numerical method of structural mechanics ‒ the finite element method ‒ were also used. Analysis of the performance of structural options was carried out using the SCAD design and computing complex (Ukraine). A separate direction in the work was design developments, which included methods for engineering assessment of the accuracy and reliability of the results obtained.

Findings. An analytical expression for determining the vertical pressure of bulk material is obtained, which reflects in a closed form the regularities of its distribution for the case of a straight inclined rigid wall of the outlet part of the hopper container with an arbitrary cross-sectional shape. The pressure value of the bulk material according to this expression quantitatively exceeds the pressure value according to known analytical models. This gives grounds to believe that when loading the hopper structures, a change in the structure of the bulk material occurs, which is described in the literature as its loosening.

Originality. The conducted researches allowed for the first time to establish the regularities of the pressure distribution of bulk material during static operation of a hopper structure with straight inclined walls. The obtained expression is structurally the product of two power functions, in which the exponent is the expressions that reproduce the geometry of the outlet part of the hopper structure and the material of its side walls.

Practical value. The obtained expression allows to calculate the vertical and, if necessary, normal pressure of bulk material for straight inclined walls of hopper structures. It is proved that the pressure increases significantly with increasing its depth, which in the case of unloading the container should lead to the destruction of the static form of laying of bulk material. The developed model is the basis for a more detailed consideration of the characteristics of bulk material, such as the density of laying or the angle of laying.
Modern Views on the Prevalence, Gender Specificity, and Etiological Factors of Temporomandibular Disorders
Authors:   Lviv National Medical University named after Danylo Halytskyi, Lviv, Ukraine., Makeyev V. , Shybinska M. ,   Lviv National Medical University named after Danylo Halytskyi, Lviv, Ukraine.
Published: February 2025

Relevance. Temporomandibular disorders (TMD) remain a significant challenge for dentists across various specialties when diagnosing
and treating them. Thus, current data on TMD’s prevalence and potential etiological factors are crucial for the initial diagnosis.
Objective. To systematize and review modern views on temporomandibular disorders’ prevalence, gender-specific characteristics, and
etiological factors.
Materials and Methods. From 2017 to 2024, scientific and medical information was searched and systematically analyzed, including
studies by foreign and Ukrainian researchers published in English and Ukrainian. During the literature analysis, three more recent publications
were added, whose information was deemed relevant to the present.
Results of the Study. It was determined that temporomandibular disorders remain relevant in identifying their etiological factors.
The prevalence of TMD remains high, with significant gender-specific characteristics showing an increased incidence of TMD in women.
Conclusions. Due to the relatively high prevalence of temporomandibular disorders, it is necessary to emphasize the importance of
timely diagnosis of this pathology for dentists.
Keywords: temporomandibular disorders, prevalence, gender specificity, etiological factors.
Comparison of the Effectiveness of Transcutaneous Electrical Nerve Stimulation and Microcurrent Nerve Stimulation in Reducing Clinical Symptoms in Patients with Temporomandibular Joint Dysfunction
Authors:   Institute of Postgraduate Education, O. Bogomolets’ National Medical University, Kyiv, Ukraine, Proshchenko A. , Shynchukovskyi I. ,   Institute of Postgraduate Education, O. Bogomolets’ National Medical University, Kyiv, Ukraine
Published: February 2025

Abstract. Today, the prevalence of temporomandibular joint dysfunction among the world’s population is approximately 80%. Quite
often, this disease significantly impairs the quality of life, sometimes even leading to disability. Today, there are methods for treating
temporomandibular joint dysfunction with electrotherapy, including transcutaneous electrical nerve stimulation (TENS) and microcurrent
electrical nerve stimulation (MENS), which are considered promising areas for further research.
The study aimed to compare the effectiveness of TENS and MENS therapy in reducing clinical symptoms in patients with temporomandibular
joint dysfunction.
Materials and methods: 40 participants participated in the study and were randomly divided into 2 groups. Group I received treatment
with TENS therapy, and group II—MENS therapy. The frequency of treatment was 2 sessions per week, and the total duration of
treatment was 10 sessions.
Results. In comparison, between the baseline and the result at the end of 10 sessions, the HRV in group I decreased by 37.5% and in
group II —by 27.03%. When comparing the results of treatment for VAS between the baseline and 1 month after treatment, the results
in group I showed a 33.33% reduction in pain, and in group II—22.98%. The improvement in maximum mouth opening at 10 sessions
compared to the baseline in group I was 12.98% and in group II —10.67%. When comparing the indicators of maximum mouth opening
between the baseline and one month after treatment, an increase in this parameter was observed in group I by 11.87% and in group
II — by 9.43%.
Conclusions: according to the study results, the use of TENS- and MENS therapy is effective in treating temporomandibular joint disorders,
but during the treatment, TENS therapy showed slightly better results in reducing clinical symptoms. However, 1 month after
the end of treatment, the effect of electrotherapy decreases slightly, but still, the clinical symptoms are better compared to the initial
situation.
Keywords: temporomandibular joint, dysfunction, pain, electrotherapy, physiotherapy.
АНАЛІЗ І МОДЕЛЮВАННЯ ПРОЦЕСУ РУХУ СУДНА ПІД ЧАС ЗАХОДУ В КАМЕРУ ШЛЮЗУ
Authors: Гончарук І.П. , Головань А.І. , Піменова А.Ю.
Published: February 2025

У статті представлено результати дослідження гідродинамічних особливостей руху суден під час заходу в камеру шлюзу, що є складним і відповідальним маневром, особливо для великотоннажних суден. Встановлено, що в умовах обмеженого простору камери шлюзу виникають значні гідродинамічні явища, включаючи інтерференцію хвиль, підвищення рівня води перед носовою частиною судна, стиснення потоку та збільшення хвильового опору. Ці процеси суттєво впливають на параметри руху судна, зокрема на його швидкість, осідання,диферент та стабільність під час маневру. Розроблено математичну модель руху судна, яка враховує специфіку гідродинамічних умов у камері шлюзу. Вона поєднує рівняння руху судна, опис стану потоку обтікання та хвильові явища. Особлива увага приділена впливу ступеня стиснення потоку на критичні швидкості, що є важливими для оцінки безпеки та ефективності маневрування. Модель дозволяє прогнозувати поведінку судна під час заходу в шлюз, аналізувати вплив різних факторів і розробляти рекомендації для практичного застосування. Експериментальні дослідження підтвердили, що запропонована модель є ефективною для аналізу руху великотоннажних суден, які мають підвищені вимоги до точності маневрування. Результати роботи можуть бути використані для оптимізації процесів шлюзування, розробки нових підходів до навігаційного забезпечення і підвищення безпеки експлуатації шлюзів. Також вони сприяють вдосконаленню існуючих методик проектування шлюзів і процедур маневрування в обмежених водних просторах. Запропоновані підходи мають значний потенціал для інтеграції у сучасні навігаційні системи, дозволяючи враховувати складні гідродинамічні умови і зменшувати екологічні та економічні ризики, пов’язані із судноплавством у вузьких та обмежених водних шляхах.
Ключові слова: маневрування, судно, безпека судноплавства, шлюзування, критична швидкість, прийняття рішень, гідродинаміка, камера шлюзу, математичне моделювання, оптимізація, великотоннажні судна, вузькості.
ДОСЛІДЖЕННЯ ВПЛИВУ ПОГОДНИХ УМОВ НА ВМІСТ АЛЮМОСИЛІКАТІВ В СУДНОВОМУ ПАЛИВІ
Authors: Врублевський Р.Є.
Published: February 2025

У сучасних умовах судноплавства наявність алюмосилікатів у судновому паливі становить значну проблему, що впливає на надійність та ефективність роботи суднових двигунів. Збільшення концентраціїцих частинок, особливо в епоху використання низькосірчистого пального, створює значні експлуатаційні та економічні виклики для судновласників та операторів. Використання ефективних систем підготовки пального, зокрема сепараторів, сучасних фільтраційних технологій та інтеграції систем автоматичного моніторингу, є необхідним для забезпечення стабільної роботи двигунів і зменшення ризиків пошкоджень. Системи очищення та контролю за вмістом алюмосилікатів в судновому паливі не завжди справляються з цією задачею а особливо в умовах несприятливих погодних умов. Незважаючи на численні дослідження, вплив погодних умов на ефективність очищення пального досі не отримав належної уваги. З метою усунення цього пробілу та глибшого розуміння механізмів впливу погодних факторів на рівень забруднення пального, було вирішено провести експеримент у реальних умовах експлуатації судна. Цей підхід дозволяє не лише кількісно оцінити наявність алюмосилікатів у паливі, але й дослідити динаміку їх змін залежно від погодних умов. Експеримент доводить що аномально високі рівні алюмосилікатів та інших твердих домішок у паливі спричинені потраплянням домішок із дна танків через коливання та перемішування під час хитавиці або різких маневрів у несприятливих погодних умовах. Результати нашого дослідження можуть стати основою для вдосконалення систем очищення пального та впровадження систем візуального контролю за вмістом алюмосилікатів у паливі в режимі реального часу, що дозволить оперативно відстежувати рівень забруднень та мінімізувати їхній негативний вплив.
Ключові слова: дослідження, погодні умови, алюмосилікати, суднове паливо.
ПОТОЧНИЙ СТАН ДОСЛІДЖЕННЯ ПИТАННЯ ПРОГНОЗУВАННЯ МАНЕВРЕНОСТІ СУДЕН ТА ЇХНЬОЇ ГІДРОДИНАМІКИ В ОБМЕЖЕНИХ ВОДАХ
Authors: Маранов О.В. , Левченко О.В.
Published: February 2025

Метою дослыдження є оцінка сучасного стану питання прогнозування маневреності суден і їхньої гідродинаміки в обмежених водах. Для досягнення мети дослідження вивчено історію розвитку цієї галузі знань та вказані основні досягнуті на цьому шляху результати.На основі проведеного аналізу встановлений реальний стан прогнозування маневреності суден в обмежених водах і проблемні питання їхньої гідродинаміки на мілководних ділянках. Питання прогнозування руху суден є пріоритетним у зв'язку зі збільшенням розмірівсуден і вимогами щодо підвищення їхньої енергоефективності. Для цього необхідно мати сучасні надійні обчислювальні методи через можливість проведення постійних морських випробувань і модельних експериментів. Розглянуто та проаналізовано історію розвитку питання прогнозування маневреності суден і їхньої гідродинаміки в обмежених водах. Наведені відомі результати різних підходів щодо математичного моделювання гідродинамічних сил у рівняннях руху маневрених суден. Показано основні проблеми ускладнення математичних моделей маневрування. Виділено місце багатовимірних поліномів, що випливають з розкладів в ряд Тейлора, виражають гідродинамічні сили в термінах специфічних для судна гідродинамічних коефіцієнтів інерції та демпфування різного порядку. Показано шляхи, на основі яких дослідники на базі фізичних уявлень, математичних властивостей і досліджень чутливості створили структуру моделі для довільних маневрів керма з трьома ступенями свободи в заданій робочій точці. Ретельно розглянуто внесок дослідників у врахування ефекту мілководдя у загальну процедуру моделювання руху судна. Показано, що на відміну від морських випробувань, маневрові випробування в стиснутих умовах пропонують аналіз гідродинамічних сил на суднах в ідеалізованих умовах течії з точки зору жорсткої кінематики тіла, керуючих впливів і глибини води. Дослідження підтверджує, що моделювання складних течій навколо суден, які виникають при маневруванні на мілководді, все ще є складним завданням з точки зору моделювання та залучення обчислювальних ресурсів.
Ключові слова: безпека судноводіння, безпека судноплавства, стиснені води, прийняття рішень, морська справа, метод оцінки, управління судном, безпека, прийняття рішень, екіпаж судна, безпека на морі, навігація, навігаційна безпека.
АНАЛІЗ МЕТОДІВ ТА ЗАСОБІВ НЕЙТРАЛІЗАЦІЇ ВІБРАЦІЇ СУДНОВОГО ДИЗЕЛЬ-ГЕНЕРАТОРА
Authors: Шапран Ю.Є. , Тимощук О.М.
Published: February 2025

У статті з’ясовано, що перетворення в машинах і механізмах одних видів енергії на інші, перетворення форм руху, здійснення робочих процесів неминуче пов'язані з появою змінних сил, що породжують вібрацію. Вона негативно впливає на міцність та надійність роботи машин, несучих конструкцій, споруд та має шкідливий вплив на фізіологічний стан людей. При досягненні певних значень вібрація може викликати порушення робочих процесів, призвести до розладу управління та регулювання, спотворення показань приладів, до посиленого зносу та поломок машин. Більшість сучасних машин уже недостатньо характеризувати енергетичними, масогабаритними та економічними показниками, а необхідно також оцінювати їхню віброактивність. Метою статті є дослідження методів та засобів нейтралізації вібрації суднового дизель-генераторного агрегату для формування обґрунтованих рекомендацій щодо їх ремонту (модернізації). Розроблена методика призначена для визначення жорсткості, коефіцієнтів демпфування та поглинання інноваційний віброізоляторів на основі експериментальних статичних навантажувальних показників, що дозволить удосконалити суднового дизель-генераторного агрегату на етапі його модернізації. Проведено дослідження основних віброізоляційних засобів (упорів) та зроблено висновок про необхідність розробки інноваційних методів компенсації поперечних коливань верхньої частини двигунів. Побудована блок-схема методу визначення експериментальних статичних навантажувальних характеристик, жорсткостей, коефіцієнтів демпфування та поглинання інноваційних віброізоляторів, що може бути використана на етапі модернізації суднових дизель-генераторних агрегатів.
Ключові слова: морський транспорт, напівпровідникові прилади, силова електроніка, суднові двигуни, суднова електроенергетична установка, енергетична установка, судно, діагностування, ефективна потужність, передача потужності, судновий дизель.
The New Hahn Sequence Space via $(p,q)$-Calculus
Authors: Bilgin Ellidokuzoğlu Hacer , Erdem Sezer , Demiriz Serkan
Published: February 2025

In this paper, a novel generalized Hahn sequence space, denoted as $h(C(p,q))$, is introduced by utilizing the $(p, q)$-Ces\`{a}ro matrix. Fundamental properties of this sequence space, such as its completeness and inclusion relations with other well-known sequence spaces, are explored. The duals of this newly constructed sequence space are also determined, providing insights into its structural and functional characteristics. Furthermore, matrix mapping classes of the form $(h(C(p,q)):\mu)$ are characterized for various classical sequence spaces $\mu \in \{c_0, c, \ell_\infty, \ell_1, h\}$, extending the applicability of the proposed space to broader mathematical contexts. The results obtained contribute to the ongoing development of sequence space theory and its applications in functional analysis.
Inventarisasi Arthropoda pada Tanaman Tebu (Saccharum officinarum L.) Di Tiga Umur Tanaman yang Berbeda
Authors: Abidin Zainal , Dwy Ushardyna Funky , Lukman Hakim Arief
Published: February 2025

Sugarcane (Saccharum officinarum L.) is a national sugar-producing plant. One of the declines in sugar production is caused by pests and diseases and improper control. The study aims to make an inventory of arthropods in sugarcane at the age of 1,5 – 3 months, 4 – 10 months, and < 11 months in order to obtain information on these matters. The research was carried out in three plantation areas in Sumber Perkul, Gedangan, Malang and at the Basic Laboratory of the Universitas Islam Raden Rahmat Malang during March – May 2022. This study used the relative method (Sticky yellow traps, pitfall traps, light traps) and the absolute method (visual control). The results of this 14.932 individu, study obtained 68 families from the Arachnida and Insecta classes, with groups of predatory roles, parasitoids, herbivores and others. The Important Value Index of dominant natural enemies (Parasitoid) Dolichopodidae (45%), Detritivor arthropod (Drosophilidae) and Polinator arthropod (Noctuidae) (26%), Herbivora arthropod Delphacidae (15%), and natural enemies (Predator) Coccinelidae (14%).  The conclusion is that from all the calculated indicators there is no group of arthropods that dominates, the diversity is moderate, and the distribution is evenly distributed. There is a change in composition, but in all indicators the calculation of the entire age of the sugarcane plant is still in the stable and balanced category.
Peranan Mikroorganisme Pendegradasi Plastik: Tinjauan Biodegradasi Plastik, Mekanismenya, serta Mikroorganisme yang Berperan
Authors: Arista Putu Cindy
Published: February 2025

Plastic is difficult to decompose in nature because it is a synthetic polymer made by humans and is made from petroleum. The problem that arises from the uncontrolled use of plastic is the accumulation of plastic waste in the environment which is not handled properly and becomes a source of environmental pollution. Plastic waste creates various kinds of environmental problems that disturb the balance of ecosystems and have an impact on the life of organisms in the environment. To overcome this problem, it is necessary to carry out related research as an effective solution for dealing with plastic waste. Biodegradation is one of the right methods for dealing with plastic waste now and in the future. However, there is limited review of the bio-decomposition of plastics, the microbial species present, the effectiveness of degradation, and the mechanisms involved. Based on this, this research focuses on a brief review of plastic biodegradation such as the factors that affect biodegradation, the species of microorganisms that play a role in the degradation of macro and micro-plastics, as well as the mechanism of plastic degradation through enzymes from the viewpoint of microorganisms. Various species of microorganisms such as bacteria, algae and fungi have the ability to decompose plastics but they cannot mineralize plastics completely. Meanwhile, research on the enzymes involved in plastic degradation is still limited, especially in the case of algae. This review can be a reference for researchers to find effective strategies to address the problem of plastic waste worldwide.
KANDUNGAN MINERAL DAN LOGAM BERAT PADA BIOSALT RUMPUT LAUT Padina sp.
Authors: Riska Nurdiana , Suedy Sri Widodo Agung , Izzati Munifatul
Published: February 2025

Indonesian is an archipelago that has abundant biological resources, one of which is seaweed. Seaweed is widely used by the community as a standard cake chart, agar and herbal medicinal ingredients. One of the potential of seaweed can produce mineral salts (biosalt). One of the seaweed Biosalt which has not been widely used is from Padina sp. Biosalt Padina sp. contains minerals needed by the human body. The purpose of this study was to determine the amount of salt yield obtained from seaweed Padina sp. and knowing the quality of salt from Padina sp. in terms of the content of macromineral (Ca and Mg), Micromineral (Fe, Mn and Zn) and heavy metals (Cu and Pb). Sampling of Padina sp. Seaweed conducted in Teluk Awur, Jepara. Extraction biosalt Padina sp. carried out at BSF Plant Laboratory, Department of Biology, FSM, UNDIP. Testing with the ICP-OES tool was carried out in the Physical Chemistry laboratory of FMIPA UNNES. Data analysis was descriptive qualitative by comparing the salt content of "biosalt" seaweed with table salt (control). The results showed that the total yield of seaweed biosalt was 9.44 gr / 100 gr or 9.44%. As for that the mineral content of Ca, Mg, Fe, Mn, and Zn in biosalt Padina sp. higher than in table salt. On the other hand, heavy metals Cu and Pb in biosalt Padina sp. lower than table salt. This shows that salt obtained from seaweed Padina sp. safe for humans because they have high mineral content and heavy metal levels which are still below the threshold (<2.0 mg / gr) Keywords: minerals, heavy metals, seaweed, biosalt.
KANDUNGAN MINYAK ATSIRI ANDALIMAN (Zanthoxylum acanthopodium DC) DAN BIOAKTIVITASNYA
Authors: Silalahi Marina , Lumbantobing Karen
Published: February 2025

Andaliman (Zanthoxylum acanthopodium) is a species belonging Rutaceae, widely used as a spice and traditional medicine, especially by the Batak ethnic group in North Sumatra. Until now, in-depth studies on the botanical and utilization of Z. acanthopodium is limited. This study is based on literature studies on various research results published online, especially on Google scholars. Some of the keys used include: Z. acanthopodium, uses of Z. acanthopodium, essential oil of Z. acanthopodium and bioactivities of Z. acanthopodium. The ethnobotany studies of Z. acanthopodium have been used in meat and fish processing which results in a distinctive flavor and longer lasting food. In the traditional Z. acanthopodium use as mouth fresheners, dental care, treat asthma, cure rheumatism, cure coughs, ingredients for making health drinks. The Z. acanthopodium has anti-cancer and anti-microbial bioactivity associated with its essential oil. The compound of dictammine and skimmianine have anticancer activity against leukemia P-388 murine cells. The activity of Z. acanthopodium as an anti-microbial is very potential to be developed as a food preservative while preventing cancer.
ANALISIS PERTUMBUHAN DAN KANDUNGAN TOTAL FLAVONOID KULTUR KALUS KRISAN (Chrysanthemum morifolium Ramat) DENGAN PEMBERIAN ASAM 2,4-DIKLOROFENOKSIASETAT (2,4-D) DAN AIR KELAPA
Authors: Setiawati Tia , Levi Astuti Anggita , Nurzaman Mohamad , Ratningsih Nining
Published: February 2025

Chrysanthemum morifolium contains flavonoids which have antioxidant properties and was useful in treating various diseases. The production of flavonoids from plants can be done in vitro through callus culture. Auxin 2,4-D growth regulators and organic compounds such as coconut water added to the media can affect the success of callus formation and secondary metabolite synthesis. The purpose of this study was to obtain the best treatment of 2,4-D concentration and coconut water that can increase the growth and total flavonoid levels of C. morifolium callus cultures. The method used in this research was the experimental method completely randomized design (CRD) with 8 treatments, namely 1 ppm 2,4-D + 10% coconut water (CW); 2 ppm 2,4-D + 10% CW; 3 ppm 2,4-D + 10% CW ; 4 ppm 2,4-D + 10% CW; 1 ppm 2,4-D; 2 ppm 2,4-D; 3 ppm 2,4-D; 4 ppm 2,4-D in 4 replication. The results showed that the treatment of 4 ppm 2,4-D and 10% CW was the best treatment combination, resulting in an average callus size (1.4 cm), fresh weight (0.19 grams), dry weight (0.16 gram) and total flavonoid content (1.873 mgQE/g)
CATATAN KELOMPOK ASCOMYCOTA MAKROSKOPIK DI INDONESIA
Authors: Permana Putra Ivan
Published: February 2025

Ascomycota is the largest Phylum in the Kingdom of Fungi. Most of the members of this group are microscopic, but fews are also produce macroscopic ascomata. Due to their large size and visible without the aid of a microscope, this group is often confused as Basidiomycota. This paper is a literature-based quantitative research. To date, 11 macroscopic Ascomycota from Indonesia have been reported, namely: Elaphomyces tropicalis sp. nov., Chlorociboria cf. aeruginosa, Podostroma cf. cornu-damae, Onygena sp., Morchella aff. deliciosa, Morchella sp., Scutellinia sp., Trichaleurina javanica, Cookeina speciosa, Cookeina tricholoma, Phillipsia sp., Daldinia spp., and Xylaria spp. The macrofungi are classified into 5 orders and 9 Families. Exploration and inventory efforts are need to be done more actively to increase the information on the diversity of masroscopic Ascomycota in Indonesia.
Distribusi Pandanus Di Pulau Wangi-wangi Kabupaten Wakatobi Sulawesi Tenggara
Authors: Husdiati  , Hendra Medi , Oktavianingsih Linda
Published: February 2025

Pandanus is a plant that has two houses (dioecious) that have morphological like shrubs or trees and is difficult to find shelter in another tree, prop roots, and single leaves that mostly have spines along the edges and the base of the leaf. The purpose of this research is to determine the distribution of the Pandanaceae family on Wangi-wangi Island, Wakatobi Regency. The method used field observation technique and data collection done by exploring the Wangi-wangi Island, Wakatobi Regency area. The result of the research is two distribution patterns of Pandanus on Wangi-wangi Island is spread throughout the island for the type of Pandanus tectorius Soland. and Pandanus amaryllifolius Roxb. while the other two species, Pandanus tectorius var. variegatus Back. and Pandanus dubious Spreng. found only on the west side only.
Collatz Sequence Proof (1st Way)
Authors: Muhammad Taha
Published: February 2025

Abstract of Solving Collatz Sequence I started from a loop containing all positive numbers and performed Collatz law on each number x in the loop, obtained algebraic equations, and defined the values of x, which not belong to the set of natural numbers except 1. Then I applied Collatz laws and obtained the elements of the loop, which are {4, 2, 1}. S (n)= {n/2 or 3n+1, ..., 4,2,1} for all N+. Thus LS (n) = {4,2,1} for all N+. I added extra work to support my proof: 1- Graph 2- Sketch 3- Chart 4- Table 5- Pattern 5- [If LS (n)= {4,2,1} for r = 3k] True Then I proved that [LS (n) = {4, 2, 1} for r+3= 3(k+1)] True 6- [If LS (n) has no loop if for r = 3k+h, h<3, h is a natural number] True Then I proved that [LS (n) has no loop if for r+1 = 3k+h+1=3k+2, h=1] True Therefore: LS (5) = LS (10^100) = LS ((10^1000) + 7) = LS (47) = ... = LS (1) = {4, 2, 1} only for all n in N+ Note: r = # of elements in a loop. K = 1 or 2
Construction of a novel gene signature linked to ferroptosis in pediatric sepsis
Authors: Fan Mingyuan , Chen Meiting , Gao Yongqi , Jiang Huilin , Li Yanling , Zhu Gongxu , Chen Shengkuan , Xu Yiming , Chen Xiaohui
Published: February 2025

Introduction

Pediatric sepsis is a complex and life-threatening condition characterized by organ failure due to an uncontrolled immune response to infection. Recent studies suggest that ferroptosis, a newly identified form of programmed cell death, may play a role in sepsis progression. However, the specific mechanisms of ferroptosis in pediatric sepsis remain unclear.

Methods

In this study, we analyzed microarray datasets from pediatric sepsis and healthy blood samples to identify ferroptosis-associated genes. A protein-protein interaction (PPI) network analysis and histological validation were performed to identify key genes. Additionally, immune infiltration analysis was conducted to explore the correlation between immune cells, immune checkpoint-related genes, and key genes. A competing endogenous RNA (ceRNA) network was constructed to investigate potential regulatory mechanisms involving long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and key ferroptosis-related genes.

Results

We identified 74 genes associated with ferroptosis in pediatric sepsis. Among them, five key genes (MAPK3, MAPK8, PPARG, PTEN, and STAT3) were confirmed through PPI network analysis and histological validation. Immune infiltration analysis revealed significant interactions between immune cells and key genes. The ceRNA network provided insights into the regulatory relationships between lncRNAs, miRNAs, and ferroptosis-related genes.

Discussion

These findings enhance our understanding of the role of ferroptosis in pediatric sepsis and highlight potential therapeutic targets for future research and clinical interventions.
Prion protein fragment (106–126) activates NLRP3 inflammasome and promotes platelet-monocyte/neutrophil interactions, potentially contributing to an inflammatory state
Authors: Verma Rashmi , Kailashiya Jyotsna , Mukherjee Avijit , Chaurasia Rameshwar Nath , Dash Debabrata
Published: February 2025

Introduction

Prion diseases are neurodegenerative disorders where infectious prion proteins (PrP) featuring an amyloidogenic amino acid sequence, PrP (106–126), accumulate in the brain leading to neuroinflammation while it can also access circulation by breaching the blood-brain barrier. Platelets are highly sensitive cells in blood, which have been widely employed as “peripheral” model for neurons. In addition to their stellar roles in hemostasis and thrombosis, platelets are also known to function as immune cells and possess necessary components of functional inflammasome. This study demonstrates that prion proteins drive inflammasome assembly in platelets and upregulate activity of caspase-1, a critical readout of functional inflammasomes.

Methods

Flow cytometric analysis was performed to measure intracellular ROS levels, caspase-1 activity, and platelet-monocyte/neutrophil interactions. Microscopy was used to assess the co-localization of NLRP3 and ASC.

Results

Inflammasome activation is fuelled by reactive oxygen species (ROS) generated in prion-stimulated platelets that eventually leads to formation of platelet-monocyte/neutrophil aggregates, which was prohibited by small-molecule inhibitors of either caspase-1 or ROS.

Discussion

Thus, in addition to their neurotoxic effects on neuronal cells and stimulation of pro-coagulant activity in platelets, prions also unleash an inflammatory response in the organism.
Molecular docking, free energy calculations, ADMETox studies, DFT analysis, and dynamic simulations highlighting a chromene glycoside as a potential inhibitor of PknG in Mycobacterium tuberculosis
Authors: Alruwaili Muharib , Elsaman Tilal , Mohamed Magdi Awadalla , Elderdery Abozer Y. , Mills Jeremy , Alruwaili Yasir , Hamza Siddiqa M. A. , Mekki Salma Elhadi Ibrahim , Alotaibi Hazim Abdullah , Alrowily Maily J. , Althobiti Maryam Musleh
Published: February 2025

Introduction

Tuberculosis (TB), caused by the Mycobacterium tuberculosis (M.tb), remains a serious medical concern globally. Resistant M.tb strains are emerging, partly because M.tb can survive within alveolar macrophages, resulting in persistent infection. Protein kinase G (PknG) is a mycobacterial virulence factor that promotes the survival of M.tb in macrophages. Targeting PknG could offer an opportunity to suppress the resistant M.tb strains.

Methods

In the present study, multiple computational tools were adopted to screen a library of 460,000 molecules for potential inhibitors of PknG of M.tb.

Results and discussions

Seven Hits (1–7) were identified with binding affinities exceeding that of the reference compound (AX20017) towards the PknG catalytic domain. Next, the ADMETox studies were performed to identify the best hit with appropriate drug-like properties. The chromene glycoside (Hit 1) was identified as a potential PknG inhibitor with better pharmacokinetic and toxicity profiles rendering it a potential drug candidate. Furthermore, quantum computational analysis was conducted to assess the mechanical and electronic properties of Hit 1, providing guidance for further studies. Molecular dynamics simulations were also performed for Hit 1 against PknG, confirming the stability of its complex. In sum, the findings in the current study highlight Hit 1 as a lead with potential for development of drugs capable of treating resistant TB.
Diversity is key: fantasy football dream teams under budget constraints
Authors: Gullholm Josef , Klünder Jil , Rowlett Julie , Stålberg Jonathan
Published: February 2025

Given a fixed budget for player salaries, what is the distribution of salaries of the top scoring teams? We investigated this question using the wealth of data available from fantasy premier league football (soccer). Using the players’ data from past seasons, for several seasons and several different budget constraints, we identified the highest scoring fantasy team for each season subject to each budget constraint. We then investigated quantifiable characteristics of these teams. Interestingly, across nearly every variable that is significant to the game of football and the budget, these top teams display diversity across these variables. Furthermore, randomly assembled teams would statistically not display such diversity across these variables. Our results indicate that diversity across these variables, including salaries, is a general feature of top performing teams. Moreover, in the process of obtaining these results we developed a data cleaning (or data reduction) algorithm that drastically reduced the amount of data to be analyzed.
Advancing personalized digital therapeutics: integrating music therapy, brainwave entrainment methods, and AI-driven biofeedback
Authors: Jiao Dian
Published: February 2025

Mental health disorders and cognitive decline are pressing global concerns, increasing the demand for non-pharmacological interventions targeting emotional dysregulation, memory deficits, and neural dysfunction. This review systematically examines three promising methodologies—music therapy, brainwave entrainment (binaural beats, isochronic tones, multisensory stimulation), and their integration into a unified therapeutic paradigm. Emerging evidence indicates that music therapy modulates affect, reduces stress, and enhances cognition by engaging limbic, prefrontal, and reward circuits. Brainwave entrainment, particularly within the gamma frequency range (30–100 Hz), facilitates neural oscillatory patterns linked to relaxation, concentration, and memory, with 40 Hz showing promise for cognitive enhancement, albeit with individual variability. Synchronized multisensory stimulation, combining auditory and visual inputs at gamma frequencies, has demonstrated potential in enhancing memory and supporting neural integrity, particularly in Alzheimer's disease. However, challenges such as patient response variability, lack of standardization, and scalability hinder widespread implementation. Recent research suggests that a synergistic application of these modalities may optimize therapeutic outcomes by leveraging complementary mechanisms. To actualize this, AI-driven biofeedback, enabling real-time physiological assessment and individualized adjustments—such as tailoring musical complexity, entrainment frequencies, and multisensory components—emerges as a promising solution. This adaptive model enhances treatment accessibility and consistency while maximizing long-term efficacy. Although in early stages, preliminary evidence highlights its transformative potential in reshaping non-pharmacological therapeutic strategies. Advancing this field requires interdisciplinary research, rigorous evaluation, and ethical data stewardship to develop innovative, patient-centered solutions for mental health and cognitive rehabilitation.