bluuebunny/crossref_metadata_2025 huggingface dataset:
BESOCIAL: A Sustainable Knowledge Graph-Based Workflow for Social Media Archiving
Authors: Lieber Sven , Van Assche Dylan , Chambers Sally , Messens Fien , Geeraert Friedel , Birkholz Julie M. , Dimou Anastasia
Published: September 2021

Social media as infrastructure for public discourse provide valuable information that needs to be preserved. Several tools for social media harvesting exist, but still only fragmented workflows may be formed with different combinations of such tools. On top of that, social media data but also preservation-related metadata standards are heterogeneous, resulting in a costly manual process. In the framework of BESOCIAL at the Royal Library of Belgium (KBR), we develop a sustainable social media archiving workflow that integrates heterogeneous data sources in a Europeana and PREMIS-based data model to describe data preserved by open source tools. This allows data stewardship on a uniform representation and we generate metadata records automatically via queries. In this paper, we present a comparison of social media harvesting tools and our Knowledge Graph-based solution which reuses off-the-shelf open source tools to harvest social media and automatically generate preservation-related metadata records. We validate our solution by generating Encoded Archival Description (EAD) and bibliographic MARC records for preservation of harvested social media collections from Twitter collected at KBR. Other archiving institutions can build upon our solution and customize it to their own social media archiving policies.
Embedding Taxonomical, Situational or Sequential Knowledge Graph Context for Recommendation Tasks
Authors: Werner Simon , Rettinger Achim , Halilaj Lavdim , Lüttin Jürgen
Published: September 2021

Learned latent vector representations are key to the success of many recommender systems in recent years. However, traditional approaches like matrix factorization produce vector representations that capture global distributions of a static recommendation scenario only. Such latent user or item representations do not capture background knowledge and are not customized to a concrete situational context and the sequential history of events leading up to it. This is a fundamentally limiting restriction for many tasks and applications, since the latent state can depend on a) abstract background information, b) the current situational context and c) the history of related observations. An illustrating example is a restaurant recommendation scenario, where a user’s assessment of the situation depends a) on taxonomical information regarding the type of cuisine, b) on situational factors like time of day, weather or location and c) on the subjective individual history and experience of this user in preceding situations. This situation-specific internal state of the user is not captured when using a traditional collaborative filtering approach, since background knowledge, the situational context and the sequential nature of an individual’s history cannot easily be represented in the matrix. In this paper, we investigate how well state-of-the-art approaches do exploit those different dimensions relevant to POI recommendation tasks. Naturally, we represent such a scenario as a temporal knowledge graph and compare plain knowledge graph, a taxonomy and a hypergraph embedding approach, as well as a recurrent neural network architecture to exploit the different context-dimensions of such rich information. Our empirical evidence indicates that the situational context is most crucial to the prediction performance, while the taxonomical and sequential information are harder to exploit. However, they still have their specific merits depending on the situation.
Adding Structure and Removing Duplicates in SPARQL Results with Nested Tables
Authors: Ferré Sébastien
Published: September 2021

The results of a SPARQL query are generally presented as a table with one row per result, and one column per projected variable. This is an immediate consequence of the formal definition of SPARQL results as a sequence of mappings from variables to RDF terms. However, because of the flat structure of tables, some of the RDF graph structure is lost. This often leads to duplicates in the contents of the table, and difficulties to read and interpret results. We propose to use nested tables to improve the presentation of SPARQL results. A nested table is a table where cells may contain embedded tables instead of RDF terms, and so recursively. We introduce an automated procedure that lifts flat tables into nested tables, based on an analysis of the query. We have implemented the procedure on top of Sparklis, a guided query builder in natural language, in order to further improve the readability of its UI. It can as well be implemented on any SPARQL querying interface as it only depends on the query and its flat results. We illustrate our proposal in the domain of pharmacovigilance, and evaluate it on complex queries over Wikidata.
Realization of a cascade treatment algorithm for glaucoma in St. Petersburg
Authors:   City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation, Antonova A.V. , Nikolaenko V.P. ,   City Multidisciplinary Hospital No. 2, St. Petersburg, Russian Federation,   St. Petersburg State University, St. Petersburg, Russian Federation, Brzheskiy V.V. ,   St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation
Published: September 2021

Aim: to analyze the duration and regimen of topical treatment and the pattern of prior laser and surgical procedures in patients with glaucoma who were admitted to the hospital for IOP-lowering interventions. Patients and Methods: this study included 500 consecutively enrolled patients who underwent surgery for uncontrolled glaucoma in 2016– 2020 and were followed up for 6–24 months. Disease history, cumulative "preservative" load, clinical examinations, and surgical outcomes were assessed. Results: preoperatively, most patients received the maximum medical therapy (i.e., three agents in two bottles). Simultaneous use of all four major classes of IOP-lowering medications occurred in 10% of patients only. Two-third of patients required surgical interventions to reduce IOP after a 6-year medical therapy. By the time of admission, 60% of patients were diagnosed with advanced or end-stage glaucoma. Prior laser or surgical procedures to reduce IOP were performed only in 142 patients and 52 patients, respectively. Treatment adherence was lower in men compared to women, irrespective of its stage. Conclusion: most patients received adequate medical therapy. However, in general, surgery was performed too late. It gives the impression that the efficacy of therapeutic and laser stages of cascade glaucoma treatment is no more than five years. In addition to the obvious drawbacks of a laissez-faire strategy (irreversible vision loss), the risk of surgical failure significantly increases. Long-term (at least 3-year) therapy using (non)fixed-dose combinations of agents containing preservatives is the major modifiable risk factor for early filtration loss. Preservativefree prostaglandin analogues improve treatment tolerability, adherence to treatment, and chances for success of IOP-lowering surgery. The authors’ results demonstrate that gender differences should be considered when planning treatment and follow-up visits. Keywords: glaucoma, IOP-lowering therapy, glaucoma surgery, ocular surface, preservatives, benzalkonium chloride. For citation: Antonova A.V., Nikolaenko V.P., Brzheskiy V.V. Realization of a cascade treatment algorithm for glaucoma in St. Petersburg. Russian Journal of Clinical Ophthalmology. 2021;21(3):123–128 (in Russ.). DOI: 10.32364/2311-7729-2021-21-3-123-128.
Treatment for neovascular age-related macular degeneration: reasonable expectations of physicians and patients
Authors:   Ophthalmology Clinic ", Durasov A.B. ,   Octopus",   (",   Tochka zreniya",   Ltd), Samara, Russian Federation
Published: September 2021

Neovascular age-related macular degeneration (nAMD) is a progressive chronic multifactorial disease requiring long-term, lifelong anti- VEGF therapy. Treatment outcomes are not always in line with the results of randomized clinical trials and do not meet the expectations for therapy whose success is assessed differently by patients and physicians. Good functional and anatomical results are expected from antivasoproliferative therapy under certain conditions, e.g., accurate evaluation of some patient characteristics (baseline visual acuity, type of choroidal neovascularization, comorbidities, status of retinal fluid and its differentiation), timely (as early as possible) treatment initiation after verifying diagnosis, and strict adherence to a proactive personalized "Treat-and-Extend" (T&E) regimen that implies a required number of injections with individual intervals. Poor adherence to treatment (non-compliance or nonpersistence of anti-VEGF therapy) significantly affects treatment outcomes in real-world clinical practice. This paper reviews criteria which predict the response to antivasoproliferative therapy and improving treatment adherence. The authors describe four fundamental principles to be met by an ideal regimen of anti-VEGF therapy for nAMD. Keywords: neovascular age-related macular degeneration, nAMD, "Treat-and-Extend", T&E, adherence, nonpersistence, anti-VEGF. For citation: Durasov A.B. Treatment for neovascular age-related macular degeneration: reasonable expectations of physicians and patients. Russian Journal of Clinical Ophthalmology. 2021;21(3):169–174 (in Russ.). DOI: 10.32364/2311-7729-2021-21-3-169-174.
Incomplete ossification of the atlas in cats: seven cases detected on computed tomography
Authors: Kemel'man Evgeniy , Kostygova Elena , Tyurenkov Ivan , Lapshin Maksim
Published: September 2021

Defects of the ventral arch of the atlas were detected on computed tomography in nine cats aged 3…12 months with signs of upper cervical injury including paina and ataxia. Seven cats have an ambulatory tetraparesis, and two cats have a nonambulatory tetraparesis. The bone defects were consistent with the normal location of the ventral arch growth areas of the atlas. In all observed cats, the pattern of ossification abnormalities was similar — the lateral portion of the arch was completely absent in seven cats on the left and in two cats on the right. The structure of the ventral tubercle was traceable in 8 of 9 cats. Also, in 8 of 9 cases an isolated bone fragment was observed lateral to the dens of the axis, the exact origin of which was not determined. This fragment was observed in 6 cases on the right, in two cases on the left, and only in two cases it corresponded to the side of the undeveloped arch. In 7 out of 9 cats, the dorsal arch was not fused; in 2 cats with complete fusion, the dorsal arch was deformed. An dens fracture was visualized in 3 cases, no hypoplasia of the dens was visualized, and one cat have atlantoaxial subluxation. Seven cats received conservative treatment and 2 cats received surgical treatment. Clinical improvement was observed in all cats. Disorder the ossification of the ventral arch of the atlas should be considered as the differential diagnosis in young cats with suspected atlanto-axial instability and trauma of the cervical spine. The authors were unable to find publications describing this atlas developmental abnormality in cats, so the authors believe that this is the first mention of incomplete ossification of the atlas in cats.
The Association Between ANKRD55 rs6859219 SNP and the Risk of Multiple Sclerosis in Iranian Patients
Authors:   Department of Biology, Faculty of Engineering, Science & Arts University, Yazd, Iran., Mandegarfard Sepideh , Pourgholaminejad Arash ,   Department of Immunology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Miresmaeili Seyed Mohsen ,   Department of Biology, Faculty of Engineering, Science & Arts University, Yazd, Iran., Shahzadeh Fazeli Seyed Abolhassan ,   Department of Molecular and Cellular Biology, Faculty of Basic Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran.
Published: September 2021

Background: Multiple Sclerosis (MS) is a neuroinflammatory autoimmune disease of the central nervous system. ANKRD55 rs6859219 Single Nucleotide Polymorphisms (SNPs) are reported as a potential novel MS risk gene, but the biological reasons underlying this correlation are still mysterious. Objectives: This study aimed to investigate the potential association of ANKRD55 rs6859219 SNP with the risk of MS in Iranian patients. Materials & Methods: Blood samples were taken from 80 patients and healthy individuals. Afterward, the effects of some related-risk factors, such as age, gender, smoking status, drug allergy, and exposure to chemicals (such as detergents, cleansing chemical, acids, etc., in their common work area or their daily home exposure) were measured on the incidence of Relapsing-Remitting MS (RRMS) patients. Polymerase Chain Reaction (PCR) was performed, and the PCR products were genotyped using the Sanger sequencing system. Results: The GT genotype of ANKRD55 rs6859219 SNP more increased in MS patients than healthy subjects, and a significant association was found between MS and the rs6859219 SNP in the single-variable association analysis (P=0.04). In the additive model, our findings indicated that the rs6859219 SNP increased the risk of MS. Additionally, the results of all crude models, additive, recessive, dominant, and overdominant, were significantly different in participants with MS compared to the controls. Conclusion: Eventually, the GT genotype of ANKRD55 rs6859219 SNP significantly increased the risk of MS compared to the TT genotype.
КЛАСИФІКАТОР МОДИФІКАЦІЙ ЦИВІЛЬНИХ ВІТЧИЗНЯНИХ ЛІТАКІВ ЯК ЕФЕКТИВНИЙ ЗАСІБ РЕАЛІЗАЦІЇ ПРИНЦИПУ МІНІМІЗАЦІЇ ВИТРАТ НА ЇХ ПРОЕКТУВАННЯ І ВИРОБНИЦТВО
Authors: Серебрянникова В. Ю. , Неделько В. Н.
Published: September 2021

The main aspects of the implementation of the classifier of modifications of domestic civil aircraft as an effective means of implementing the principle of minimizing the costs of their design and production are set. Classification levels of classes include different modifications based on signs of species that are the most common.The classifier implements the principle of forming five signs of modifications of the Wash-shrinkage: a change in the functional purpose or conversion of the aircraft, due to its application area, a change in the degree of technical execution of the air vessel and an increase in economic efficiency. Mandatory accounting for differentiation of classification levels of modifications based on the signs of the presence or absence of the functional purpose of the aircraft and the remaining four alternative classification levels of the aircraft modifications are necessary.The first classification feature is based on the basis of the highest level - the species, and the following signs are attributed to equal classification levels - classes.The developed schemes of the components of the classes in the field of application, the stake of technical perfection and an increase in the economic efficiency of the aircraft vessel are given, and the fragment of its main flight technicians is presented.The practical use of the proposed classifier is associated with the necessary analysis of the characterization of the characterization of the components of the scope of application, changes in the flight specifications, the degree of technical perfection of the IS-complete modification and a sign of increasing the economic efficiency of modifies, as well as methods and comprehensive means of implementing the components of these recognition -s. This analysis is submitted to a large volume of research work, in the first approximation to the tables below - 5. The proposed principle and implementing its approach to the formation of a classifier of aircraft modifications must pass a sufficiently long process of practical phased implementation, starting with the level of subclasses and, in particular The next levels behind them, being objectically analyzed and justified by narrow specialists working at all stages of the life cycle of the aircraft.
РОЗРОБКА СИСТЕМИ РУЧНОГО РОБОТА-МАНІПУЛЯТОРА З ДИСТАНЦІЙНИМ УПРАВЛІННЯМ
Authors: Kritskiy D. N. , Plastun T. A. , Guobadia E. M.
Published: September 2021

The aim of this research work is to research and develop a system of a hand-like remote-controlled robotic arm. Devices of this design are currently in demand in many areas of human life, in particular during rescue operations. The described device must be able to hold an object of arbitrary shape using a gripper, has acceptable positioning and control accuracy. Such a device can be used to work in a harmful or hazardous environment, thereby minimizing the harmful effects on humans. The control system of such a device must provide a protocol for transferring data from the input device to the end handle of the manipulator to perform the corresponding movement. To start the development process, market analysis was conducted, in the process of which several similar products were identified and compared against each other and the system being developed. As a result of that analysis, comparison table was created listing the main features of the system being developed in comparison to existing solutions on the market, to check whether it will be competitive at the current market.In this article, such system is proposed and later developed with the analysis of modern technical components and taking into account the accompanying scientific and technical research. In the course of the work, the analysis of existing technical solutions was carried out, the principles of operation of individual components were considered, and the process of developing the final system was described. As a processor device, it was decided to use the Arduino Uno and Arduino Nano microprocessor boards, which provide convenient tools for working with ATmega microprocessors with high performance and energy efficiency.As a result of this work, functional, logical and electrical circuits were created and described, which were used to create a working prototype of the system, as well as a diagram of the model of the manipulator body, which was printed using a 3D printer. Using the created circuits, a working prototype of the described system was built, which was successfully tested, a demonstration of which is given in the work. The created one can be integrated as a subsystem into a larger-scale project.
Sense of Belonging, Intercultural and Academic Experiences among International Students at a University in Northern Ireland
Authors: Cena Elida , Burns Stephanie , Wilson Paul
Published: September 2021

Higher education institutions have a strong interest in attracting international students, however, there is little research on international students' experience while studying in the UK and how this relates to their adjustment and belonging. This research was conducted with 16 international students at a HE institution in Northern Ireland, using qualitative interviews to examine academic and socio-cultural challenges they experience while studying and living in a country different from their own. Findings suggest that the academic challenges posed by a different educational system, issues affecting social relations within the campus, and living in a homogenous society can have an impact on the international student experience. Adjustment challenges were primarily attributable to language and cultural barriers. These findings highlight that it is vital for institutions to better understand students’ needs and tailor their services to enhance international students’ learning experience.
“It’s My Fault”: Exploring Experiences and Mental Wellness Among Korean International Graduate Students
Authors: Koo Katie , Kim Young Won , Lee Joonyoung , Nyunt Gudrun
Published: September 2021

Mental health issues are on the rise on college campuses for all students, including international students. This qualitative study explores the mental wellness of Korean international graduate students, a sub-group that has received limited attention. By interviewing 18 Korean international graduate students in the United States, we found that limited English proficiency shapes various aspects of Korean international graduate students’ well-being; self-imposed pressures negatively influence mental wellness; self-blaming and an inability to express one’s feelings lead to further deterioration; and students turn to physical and religious/spiritual activities to improve their mental wellness. Implications for research and practice are discussed.
Intercultural Effectiveness of International and Domestic Students
Authors: Avcılar Ahsen , Gök Enes
Published: September 2021

Among the vast and diverse discussions and research on international students, the intercultural status of university students holds a special place in terms of integration and academic success. One of the discussions is the intercultural competencies of the students in higher education. In this respect, this study aims to compare the intercultural effectiveness of international and domestic students, as well as examine their intercultural effectiveness status in terms of different background characteristics. The data were collected from a public university in Turkey using the Intercultural Effectiveness Scale developed by Portalla and Chen (2010). The findings revealed that international students compared to domestic counterparts show a higher level of intercultural effectiveness. Additionally, some background characteristics are significant predictors of the intercultural effectiveness of university students: grade level, parent's nationality, being and living in a foreign country, having a close friend(s) from a different culture.  Some research and policy recommendations are provided.
Navigating Through Uncertainty in the Era of COVID-19
Authors: Sustarsic Manca , Zhang Jianhui
Published: September 2021

With the spread of COVID-19 around the world, the lives of international students became affected by a sudden shift to online learning, sheltering in place, and travel restrictions. Drawing upon the stress and coping framework, this study explores the experiences and coping of international graduate students at a large Western research university in the United States. We employed a phenomenological inquiry of in-depth interviews with 20 participants. Findings reveal the increased levels of stress and anxiety among participants as they faced academic challenges, personal challenges, and immigration-related uncertainties. Over time, students developed emotion-focused and problem-focused coping strategies to minimize the impact of the pandemic on their lives. Participants’ concerns about the host country’s treatment of international students raise important questions about the future of international student mobility. Finally, this study demonstrates the need to develop emergency responding mechanisms of the host institution.
Impact of Covid-19 on International Student Support
Authors: Bardill Moscaritolo Lisa , Perozzi Brett , Schreiber Birgit , Luescher Thierry
Published: September 2021

The Covid-19 pandemic caused unique challenges to international students. Student Affairs and Services (SAS) across the higher education sector played a key role in supporting students and institutions during the pandemic. This article reports the findings of an exploratory survey with SAS practitioners from around the globe on the ways in which SAS responded to the pandemic and sought to mitigate the impact of the pandemic on students in general and international students specifically. The results demonstrate that international students were among the primary groups of students impacted by the pandemic. Specific challenges identified include mental wellbeing, inability to return home, financial hardships, fear, and uncertainty. Discrimination of certain groups was also noted. SAS intervened to assist international students in navigating these challenges across world regions, including services declared essential for international student support. Finally, financial implications and the future of international student support are explored.
Complementary feeding practices in children aged 6-23 months: An institution-based observational study
Authors: Munde Kshitij K. , Save Sushma U.
Published: September 2021

Background: Inappropriate complementary feeding practices in children may lead to adverse consequences ranging from growth failure to mortality. Intervention programs intending to optimize the practices should be based on identification of the lacunae and on the assessment of the magnitude of the problem. Aim: The aim of the study was to determine appropriateness and adequacy of complementary feeding given to children aged 6?23 months. Materials and Methods: Data regarding demographic profile, maternal education, source of information for feeding, and details of complementary feeding provided in the last 24 h were obtained from caregivers, using the standard WHO questionnaire. Chi-square test was used for determining the association between optimal feeding practices and continued breastfeeding, age-group, maternal education, and source of information. Results: The study enrolled 480 children (mean age: 12.9+5.1 month; male: female=1.22:1). 225 children (46.87%) had minimum meal frequency and 66 (13.8%) had minimum dietary diversity, 41 (11.08%) were receiving minimum acceptable diet. Only 103 mothers (21.5%) obtained the information regarding recommended complementary feeding practices from health professionals. There was a significant association between health professional being the source of information and presence of adequate dietary diversity (p<0.01) and minimum acceptable diet (p<0.01). Conclusion: Complimentary feeding practices are inadequate and thus, require an intervention of healthcare providers with better involvement.
Leukocytic picture in pediatric Coronavirus Disease-19 infection
Authors: Dey Pranoy , Das Rhitwika
Published: September 2021

Background: Coronavirus is a large family of enveloped single-stranded zoonotic RNA virus, causes a wide spectrum of disease including Coronavirus disease-2019 (COVID-19). It is a systemic disease where immunological response has been cited as the most important parameter for both COVID-19 related death as well recoveries. Among all the blood parameters, leukocytes play the most important role in mounting an immune response. COVID-19 being a novel virus has enough literature on its leukocytic picture in adult population which is being lacking in pediatrics study. Aim: The aim of the study was to study the leukocyte picture of COVID-19 positive pediatric populations admitted in Assam Medical College and Hospital. Methods: An observational study was conducted on COVID-19 positive pediatrics patients (Age >1 month–12 years) as detected by rapid antigen test/reverse transcription-polymerase chain reaction and whose blood samples could be sent for investigations. Patient’s status and leukocytic picture at the time of admission were studied. They were followed up till discharge. Results: A total 54 COVID-19 positive patients were enrolled in the study. The mean age group was 8±2 years and gender was male predominant. Out of 54 patients enrolled in the study, 38.89% had lymphocytopenia, 25.9% neutropenia, 24% normal blood picture, and 12.96% had leukocytosis. Four patients expired and 50 patients were discharged. Neutropenia was found in 100% of the mortalities. Conclusion: Lymphocytopenia is the most commonly found deranged blood parameter. Neutropenia when found in COVID-19 positive pediatrics population, signify poor prognosis.
Etiological profile of short stature in rural Rajasthan
Authors: Singh Ashwini , Masand Rupesh , Verma Chaman Ram , Khinchi Yograj
Published: September 2021

Background: Short stature is one of the most common referrals to pediatric endocrinology clinics. Approximately 3% of children in any population are found to be short. Aim: This study aims to determine the etiology of short stature and their frequency of occurrence in 2–18 years old rural pediatric population and to classify the patients with short stature using anthropometric measurements. Materials and Methods: A total of 400 patients (age: 2–18 years) were diagnosed with short stature and admitted in pediatric ward. After meticulous history collection and complete physical examination, relevant investigations were performed in all the study subjects. Appropriate statistical analysis was carried out with the collected data. Results: Out of 400 study subjects, 70.50% were boys (male: female=2.33:1). Majority (n=241, 60.5%) of the affected children were in the age group of 2–<6 years and 7–<10 years. Of the 400 study subjects, 95% of cases (n=380) were classified as having proportionate short stature and the rest (n=20, 5%) had disproportionate short stature. Undernutrition (n=117, 29.25%) and familial short stature (n=90, 22.50%) were the leading causes of short stature. Conclusion: The current study helped to determine the etiological profile of short stature in children of adjoining rural population and in devising appropriate strategies for management and prevention.
Regional disparities in prevalence of obesity among school-aged children in Egypt: A country case study from The Eastern Mediterranean Region
Authors: Al-Jawaldeh Ayoub , Abul-Fadl Azza
Published: September 2021

Background: This study is a review of recent research conducted in Egypt on the problem of rising prevalence rates of obesity among school-aged children. Methods: The search was conducted in three phases. The key words used were obesity, overweight, school-aged children, and nutritional status specifically for Egyptians over the past decade (2010–2021). Online research sites and the libraries of the Egyptian universities of the eluc.org. websites were searched along with on-site visits to the libraries of thesis universities and other research institutes in Egypt, to obtain full research material. Finally, retrieved data were analyzed statistically. Results: The search identified 24 studies that covered 15 governorates and one national survey that covered 25 governorates. The prevalence of obesity in the pooled populations was 10.6%. Prevalence rates of obesity were highest in Lower Egypt (LE) (10.0%) and urban governorates (9.2%) compared to Upper Egypt (UE) governorates (6.3%, p>0.05). Obesity in the children over 10 years was slightly higher among females in the urban (5.1%) and LE governorates (5.2%) compared to males (4.1 and 4.8%, respectively). However, it appeared higher in males (5.2%) compared to females (3.2%) in UE governorates (p>0.05). Conclusion: Obesity in Egypt is rising and is related primarily to high consumption of unhealthy foods. Member states must take active steps to regulate marketing of unhealthy foods to children.
Anesthetic management of a parturient with Eisenmenger’s syndrome: A case report
Authors: Singh Anshul , Patel Nishant
Published: September 2021

Eisenmenger’s syndrome results from certain uncorrected congenital abnormalities of the heart facilitating left to right shunt and chronic volume overload of the pulmonary vasculature, leading to irreversible changes in the pulmonary vasculature. Pregnancy in the patients of this syndrome is associated with a high risk of cardiovascular decompensation, thromboembolic complications, and sudden cardiac death. We present the case of a 25-year-old pregnant woman with Eisenmenger’s syndrome who delivered through the vaginal route at 37 weeks of gestation, under labor epidural anesthesia. A healthy male baby was delivered within 40 min of drug deposition in the epidural space. The postpartum period was essentially uneventful with successful maternal and neonatal outcomes.
Silent perforation and migration of IUCD: A diagnostic challenge in patients with pain abdomen: A case report
Authors: Srirambhatla Annapurna , Narayanam Srinivasa , Kannepalli Poornima Lakshmi
Published: September 2021

Secondary perforations of intrauterine contraceptive devices (IUCD) may be clinically silent. The patient may not report the missing threads due to a lack of acute symptoms or under the impression that the device could have been expelled. We present a case of a 42-year-old lady treated for renal cell carcinoma and presenting with recurrent right lower quadrant abdominal pain for 2 years. Ultrasound scans did not reveal any abnormality. A plain computed tomography (CT) revealed a migrated IUCD embedded in the omentum with adjacent inflammation. Although CT is not the modality of choice in the diagnosis of migrated IUCD, it proved helpful in diagnosing this case as history was not forthcoming. This case highlights the diagnostic dilemma faced in cases of silent IUCD migration presenting with pain abdomen. It is important to counsel the patient at the time of IUCD insertion for the early recognition of missing devices and prompt diagnosis of complications.
Unusual pericuff leak around proseal-laryngeal mask airway corrected by clamping gastric drain port: A case report
Authors: Mustahsin Mohd. , Bhoi Debesh
Published: September 2021

ProSealTM-Laryngeal Mask Airway (PLMA) (Laryngeal Mask Company, Henley-on Thames, UK) is commonly used for securing the airway with an added advantage over classic LMA as its gastric drain tube allows the insertion of Ryle’s tube and suctioning of gastric contents. The ProSeal LMA is designed in such a way that it allows controlled mechanical ventilation. During controlled mechanical ventilation, air leaks can occur because of positive airway pressures. Air leaks from the gastric drain port are almost always due to the malposition of PLMA. Here, we report a case of air leak from gastric drain port despite correctly placed PLMA and its successful management without removing the device.
Case series of seven cases of urticaria, angioedema, and anaphylaxis (LTP syndrome) due to foods (nuts, lentils, and citrus foods) related to tree pollen (Prosopis juliflora and Holoptelea integrifolia) sensitization
Authors: Kathuria P C , Rai Manisha
Published: September 2021

Lipid transfer protein syndrome (LTPS) results from a primary sensitization to LTP belonging to the PR-14 family of pathogenesis-related PR-proteins which are plant food allergens, stable against heat and digestive enzymes, and can induce systemic reactions of urticaria, angioedema, and anaphylaxis. Here, we report a case series of seven patients with nsLTP syndrome. Our six cases of LTPS were significantly sensitized to Prosopis juliflora and Holoptelea integrifolia and one case was sensitized to H. integrifolia only. In our seven cases, we hypothesized that symptoms of hypersensitivity reaction to foods were due to cross-reactivity by IgE reactive protein of ns-LTP as a major allergenic protein in foods.
A case of guillain-barré syndrome associated with post-covid infection during 2nd wave of coronavirus in india
Authors: Behera Anil Kumar , Hassan Syed Naqueeb ul , Challa Chaitanya , Madhusudhan Reddy K Divya , R Bhardwaj V Bharat , Athahullah Athahullah , Reddy K Manaswini
Published: September 2021

The novel coronavirus-COVID-19 was detected in Wuhan city of Hubei Province in China on December 31, 2019. Coronaviruses are known to infect multiple organ systems, with respiratory complications being the most obvious symptoms. Although, neurological manifestations are quite rarely reported in cases of COVID-19. In this report, we present the case of a 57-year-old male patient reported with complaints of acute progressive symmetric quadriparesis and recently recovered from COVID-19. Two weeks prior to hospitalization, the patient suffered from cough and fever. The reverse transcriptase-polymerase chain reaction test for COVID-19 infection was positive. Electrodiagnostic tests showed that the patient had acute motor and sensory axonal neuropathy variant of Guillain-Barré Syndrome (GBS). COVID-19 virus stimulates the inflammatory cells and as a result, creates immune-mediated processes. GBS is an immune-mediated disorder. It is not clear whether COVID-19 infection induces the production of antibodies against specific gangliosides. Further investigations should be conducted in regards to the mechanism of GBS in patients with COVID-19 in the future.
Use of resting state-functional magnetic resonance imaging to assess the utility of focused meditation in post-coronavirus disease cognitive dysfunction
Authors: Kapoor Atul , Mahajan Goldaa , Kapoor Aprajita
Published: September 2021

Post-coronavirus disease (COVID-19) syndrome is a well-recognized entity in which cognitive brain dysfunction is the most common presentation. Diagnosis and management of such patients are challenging. We describe an important brain finding of post-COVID-19 syndrome on resting (rs)-functional magnetic resonance imaging by mapping the default mode network of the brain which becomes dysfunctional thus causing patient symptoms and its correction by the technique of focused meditation.
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Authors: Cover Cover
Published: September 2021

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STUDI KARAKTERISKTIK GELOMBANG PADA FLOATING BREAKWATER TIPE TERPANCANG DAN TAMBAT
Authors: Sujantoko Sujantoko , Wardhana Wisnu , Djatmiko Eko Budi , Armono Haryo Dwito , Putro Wahyu Suryo , A. Rizki Haryono
Published: September 2021

Floating breakwater (PGT) is designed to be applied as a wave barrier to reduce beach abrasion and wave energy so that waves coming to the beach have their energy reduced. Compared to conventional breakwater structures, PGT structures are more advantageous if the area to be protected from impact waves has a large enough depth. This structure is more flexible because the elevation follows the tides, so this structure can be used as a wharf at the same time. It is also free from the scouring and sedimentation that often occurs on the feet of conventional breakwater structures. This study aims to attenuate and reflect waves from various PGT configurations of piling and mooring types, by testing the physical model of PGT in the wave flume laboratory of the Department of Ocean Engineering ITS, at a water depth of 80 cm, a wave height of 3.5-5.5 cm, a wave period of 0.5-2 seconds, and the angle of the mooring rope (45o, 60o, 90o). PGT is arranged in a variety of longitudinal and transverse directions to the coast. Based on the experiment, it is known that the effect of configuration and width on the PGT structure on wave transmission and reflection is influenced by the mooring angle. Configuration 3 with the largest width can give the best transmission coefficient Kt = 0.797 at 45o mooring angle and reflection coefficient Kr = 0.572 at 90o mooring angle. In type 3 fixed-configuration gives the greatest value Kt = 0.431-0.623 and Kr = 0.053-0.997 compared to other configurations. Because in configurations 1 and 2 the back of the structure is not supported by piles, so a swing occurs which generates waves. While the effect of the slope of the wave, Kt will increase as the number of waves slopes decreases, conversely the value of Kt decreases with the increase in the slope of the wave.Keywords: Floating breakwater, piling, tethered,  mooring
Covid-19 Enfeksiyonunun ARDS komplikasyonunda IL-10 ve IL-10 (-1082G/A) Gen Varyasyonunun Potansiyel Rollerinin İncelenmesi
Authors: ALKANLI Nevra , AY Arzu
Published: September 2021

COVID-19 yeni koronavirüs hastalığı olarak bilinmektedir ve COVID-19 enfeksiyonundan kaynaklanan komplikasyonlar yaş, cinsiyet ve komorbiditeler gibi çeşitli faktörlere bağlı olarak değişmektedir. Tüm yaş gruplarını etkileyebilen COVID-19 enfeksiyonu etkilenen popülasyonların bireysel özelliklerine bağlı olarak doğrulanmış vakaların bir kısmında ciddi rahatsızlık ve ölüm nedeni olarak ortaya çıkabilmektedir. Bu enfeksiyon özellikle yaşlı bireylerde ve hipertansiyon, diabetes mellitus, astım gibi komorbiditelere sahip kişilerde daha şiddetli seyretmektedir. Ancak COVID-19 enfeksiyonunun oldukça genç olan bireylerde de görülebileceği bildirilmiştir. Bu yüzden doku proteinlerinin ekspresyon düzeyleri gibi intrinsik faktörlerin yanısıra, genetik varyasyonlar gibi genetik faktörler de enfeksiyon patogenezine katkıda bulunabilmektedir. COVID-19 hastalarının yarısından fazlasında en sık görülen komplikasyonlardan biri yoğun bakım tedavisi gerektiren ARDS (Akut Solunum Sıkıntısı Sendromu) dir. COVID-19’da viral enfeksiyona yanıt olarak İnterlökin-10 (IL-10) gibi sitokinler salınmaktadır. COVID-19 enfeksiyonu sırasında gelişen sitokin fırtınası kontrolsüz inflamasyona neden olmaktadır. Böylece çoklu organ yetmezlikle-ri gelişebilmekte ve ARDS ile ilişkili sendromlar indüklenebilmektedir. Sitokin fırtınası COVID-19 hastalarında anlamlı derecede artmış IL-10 düzeyleri ile ilişkilendirilmiştir. ARDS patogenezinde inflamasyon önemli bir belirteçtir. Proinflamatuar ve antiinflamatuar sitokinler arasındaki dengesizlik sonucunda ARDS gelişebilmektedir. IL-10 geninin promotör bölgelerindeki genetik varyasyonlar sonucunda IL-10 mRNA ve protein düzeylerinde değişiklikler ortaya çıkmaktadır. IL-10’un patolojik proinflamatuar işlevi engelleyerek COVID-19 enfeksiyonundaki mortalitenin azalmasına katkı sağlayabileceği düşünülmektedir. ARDS gelişen COVID-19 hastalarında IL-10 geninin promotör bölgesinde tanımlanan IL-10 (-1082G/A) gen varyasyonu genotip dağılımlarına göre IL-10 ekspresyon düzeylerinin belirlenmesi, ARDS’nin patolojik mekanizmalarının daha iyi anlaşılabilmesi ve ARDS’ye yönelik terapötik stratejilerin geliştirilebilmesi bakımından oldukça önemlidir. Bu derlemede COVID-19 enfeksiyonunda gelişen ARDS komplikasyonunda IL-10 ve IL-10 (-1082G/A) gen varyasyonlarının rolünün incelenmesi amaçlanmıştır.
DEMÔNIOS E HERESIA NA “RELAÇÃO DA MISSÃO DA SERRA DA IBIAPABA”, DO PADRE ANTÔNIO VIEIRA
Authors: Cristina Santos Fernanda
Published: September 2021

O texto “Relação da missão da serra da Ibiapaba”, escrito pelo padre Antônio Vieira em 1660, relata o culminar de uma série de tentativas de catequizar (e converter ao cristianismo) os indígenas tabajaras. Após uma série de acontecimentos trágicos e ações infrutíferas em adentrar nos sertões do Ceará e do Maranhão, Vieira escreve vários documentos defendendo a missão a Ibiapaba. Na “Relação...”, o inaciano dá conta de uma série de observações sobre o modo de vida do povo tabajara, os seus costumes e crenças e a forma como os protestantes holandeses avançavam na mesma região. Pretende-se analisar, neste artigo, a forma como o padre Vieira traduz os costumes e crenças tabajaras para uma linguagem cristã e uma ótica católica que, longe de considerar os tabajaras como primitivos ou selvagens, considera-os aptos a construir alianças com os holandeses e a serem dominados pelo demônio, como qualquer cristão. A heresia dos tabajaras é comum, numa tentativa de desafiar os inacianos. A partir de aportes teóricos, tais como François Hartog, que refere como retórica da alteridade o conjunto de traduções que transportam “o outro ao mesmo” (1999, p. 268), analisa-se aqui o relato de Vieira a partir de categorias fulcrais na aferição do outro, tais como nomeação, classificação, inversão ou conversão.

Palavras-chave: “Relação da missão da serra da Ibiapaba”/Antônio Vieira. Tabajaras. Demonização
NAS ORIGENS DO ROMANCE E DO GÓTICO NO BRASIL
Authors: Augusto P. Silva Daniel , França Júlio
Published: September 2021

Tomando como pontos de partida (i) as imbricações entre o nascimento do romance moderno e a literatura gótica e (ii) a extensiva recepção da obra de Ann Radcliffe (1764-1823) no Brasil, o artigo analisa as convenções góticas que se fazem presentes nos romances O filho do pescador (1843) e Tardes de um pintor ou As intrigas de um jesuíta (1847), de Antônio Gonçalves Teixeira e Sousa (1812-1861). O foco da análise recairá sobre a estratégia narrativa conhecida como “sobrenatural explicado”, tradicionalmente associado à escritora inglesa.Palavras-chave: Romance; Gótico; Teixeira e Sousa.
BAILE DE MÁSCARA NÃO É PARA PRETO DE FAVELA
Authors: Aparecida Hilário Rosangela , Veloso Ribeiro Igor , Caetano Marcio
Published: September 2021

Neste artigo refletimos como a favela, que o racismo transformou em gueto voltado para a pretitude, está se organizando para viver e sobreviver com as novas regras impostas pela pandemia causada pelo Covid-19. O objetivo é identificar as condições teóricas, as práticas e as políticas que delimitam as existências e resistências para homens pretos de favelas, suas interações corporais e espaciais, direcionadas à adaptação às novas exigências de convivência social que incluem, por exemplo, o uso de máscaras, isolamento social e demais medidas sanitárias. As conclusões até o momento indicam que a espacialidade, corporeidade e governabilidade são demarcadas pela necropolítica levada à efeito pelo Estado brasileiro e perpassadas pela aliança do crime organizado com o fundamentalismo religioso. Outrossim, compreendemos a produção das subjetividades como resultante dos modos de ser, estar e pensar. Nesse sentido, elaborar tais representações nos ajudam a entender não apenas o enredo marcado pelas subjetividades associadas a terrenos marcados pelas desigualdades sociais e violência, mas a seus novos arranjos e estratégias de enfrentamento das demandas que emergem do contexto da pandemia pela Covid-19.Palavras-chave: Racismo. Narcotráfico. Epistemologias Periféricas.
AS EPÍSTOLAS DE CÍCERO NO EXÍLIO COMO NARRATIVA DE SEU DESCENSUS
Authors: De Sousa Silva Frederico
Published: September 2021

Cícero, além de um dos grandes autores da vasta literatura latina, foi importante ator político em uma das épocas cruciais da história de Roma. E como um dos mais importantes homens de seu tempo, obteve sucessos bem como decepções, como o triste momento do autoexílio em 58 a.C., período em que sofreu perseguições, perdeu a liberdade e bens. O presente artigo faz leitura desse período vivido por Cícero e associa esse tempo à denominada catábase, aqui lida de forma metafórica, em que o sair da própria pátria apresenta significações tão intensas quanto o descensus ao mundo inferior.Palavras-chave: Cícero. Roma antiga. Exílio. Descensus
MORTE E VIDA PEREGRINA
Authors: Vecchio Alves Daniel
Published: September 2021

Muitas narrativas bíblicas, clericais e poéticas da Idade Média falam das coisas espirituais por meio de sua semelhança analógica com as coisas terrenas e corporais, analogias que se revelam como um grande esforço medieval de fixar, na alma, a crença na salvação e sua complexa rede de virtudes espirituais e vícios terrenos, interagindo, assim, com seus espaços imaginários de recompensas e punições. Para melhor compreender a representação dos diversos espaços imaginários que faziam e fazem parte da cosmologia cristã, observaremos, neste artigo, alguma das sutilezas histórico-culturais que fundamentaram os inúmeros percursos espirituais representados especificamente durante o Baixo Medievo, percursos que vão da busca pelo paraíso terreno no grande mar ainda desconhecido à busca pelo purgatório em diferentes planos espirituais. Para tanto, analisaremos, primeiramente, a representação da busca do paraíso terreno na marítima peregrinação da Navigatio Sancti Brendani Abbatis, de São Brandão (séc. VI) que passaram a ser redigidas a partir do século X, e, por conseguinte, analisaremos brevemente a Divina Comédia, de Dante, obra representativa do purgatório como terceiro espaço, um dos destinos sobrenaturais da alma, constituído não só por elementos infernais e edênicos, mas, sobretudo, por hábitos e necessidades humanas.Palavras-chave: Imaginário medieval. Representação narrativa. Espaços intermediários.