bluuebunny/crossref_metadata_2025 huggingface dataset:
Culturing THP-1 Cells v1
Authors: C Luehr Teesha
Published: November 2019

THP-1 cells are a human monocyte suspension cell line from peripheral blood of a 1 year old infant who had acute mnocytic leukemia.
INDIVIDUOS Y ESTADIOS: UNA PROPUESTA FORMAL DESDE LA INFORMACIÓN ASPECTUAL DE LOS PREDICADOS
Authors: Casado Mancebo Mario
Published: November 2019

Una de las cuestiones más polémicas en los estudios sobre predicación es ladivisión entre predicados de individuo y predicados de estadio y si el origen deestadistinción es léxico, sintáctico o semántico. En este trabajo se ofrece, enprimer lugar, una revisión teórica crítica de las categorías de individuo y estadioy de los diferentes enfoques que se les ha dado a ambas categorías desde losdiferentes ámbitos de la gramática. En segundo lugar, se propone un análisisformal de los dos tipos de predicaciones desde la perspectiva de la informaciónaspectual de los predicados, tomando como punto de partida la información dela que constan al salir del léxico, para concluir que la llamada «coacción léxica»es, en realidad, una coacción aspectual que insertaría un Sintagma Aspecto conuna variable espacio-temporal interfiriéndose en la estructura funcional de lasestructuras referenciales de la predicación.
DANTE ALIGHIERI E A VOZ FEMININA SOBREDETERMINADA: AGONISMO E FANTASMAGORIA
Authors: Louzada Fonseca Pedro Carlos , Bottos Júnior Norival
Published: November 2019

A mulher é tema central para Dante, desde seus primeiros poemas líricos até aComédia. Nessa perspectiva temática, através do método comparativo e da análisecríticoteórica, este artigo examina a maneira pela qual o poeta se utiliza daoperação fantasmática do amor cortês para anular a voz feminina em Beatriz deVida nova e, posteriormente, como a dama florentina ressurge na Comédia dotadade voz masculina do próprio Dante em constante processo de autoescuta. Nesseaspecto mimético, o artigo pretende concluir pela observação de que a poética deDante apresenta traços de emancipação da estética medieval em direção aomoderno.
The Effect of Different Dripper Properties on Entomopathogenic Nematode Application in Drip Irrigation
Authors: ERDOĞAN Hilal , ULU Tufan Can , KUŞCU Hayrettin
Published: November 2019

There are many types of drippers with different
flow path length, flow path shape, filtration surface. EPN delivery performance
of the most commonly used four different types of drippers (in-line short path,
in-line long path, in-line cylindrical and on-line button) was examined with a
drip irrigation system in laboratory conditions. Under four different pressures
(0.5, 1, 1.5, 2 bar), EPNs were applied to 1-liter beakers with irrigation
system and discharged nematodes were counted under a stereomicroscope. The
effect of pressure on application and EPN mortality were also determined. The
results showed that there were significant differences between the discharge
ratio of EPNs from drippers. Among the four drippers, on-line button dripper sustained
the highest and fastest discharge ratio. Pressure alone had no significant
effect on delivering EPNs. However, it should be considered that long pressure
exposure may harm EPNs. Regarding our results, different irrigation drippers
have significantly different effects on EPN discharge ratio. Therefore,
optimizing drip irrigation systems for EPN applications may increase their
performance.
Bazı Tanenlerin Soğan (Allium cepa L.) Dip Çürüklüğü Hastalık Etmeni Fusarium oxysporum f.sp. cepae Üzerine Antifungal Etkisi
Authors: BEKTAŞ İdris , ÜCÜK Ceyda , KÜSEK Mustafa
Published: November 2019

Soğan (Allium cepa L.) ekim
alanlarında bir çok hastalık etmeni görülmektedir. Bu hastalık etmenlerinden en
önemlisi olan Fusarium oxysporum f.sp. cepae (FOC)’nın neden olduğu dip
çürüklüğü hastalığı önemli derecede ürün kayıplarına neden olmaktadır. Bu
çalışmada 3 farklı ticari tanen ekstraktının(Artutan K, Artutan ve Farmatan)
farklı dozları(%0.25, 0.5, 1.0, 2.0, ve 
4.0) ve ticari bir fungusit olan 
Antracol WP 70’in (%0.05) FOC misel gelişimi üzerine etkisi in vitro ortamda  incelenmiştir. Elde edilen sonuçlara göre; Artutan
ve Farmatan uygulamaları fungal misel gelişimini %57,3 ile %51,4 oranında
engellemiştir. Aynı konsantrasyondaki Artutan %57,3; Farmatan ise %51,4
oranında misel gelişimini engellemiştir. Ayrıca tüm tanen ekstraktlarının %2 ve
%4’lük konsantrasyonu ve Artutan K'nın % 1'lik konsantrasyonu FOC misel
gelişimini Antracol WP 70 den daha daha fazla baskılamıştır(p<0.05). Üç
farklı tanen ekstraktının farklı konsantrasyonları FOC'un in vitro ortamda misel gelişimine etkisi negatif kontrol ile
karşılaştırıldığında birçok konsantrasyonunun 
antifungal özellik gösterdiği belirlenmiştir. Sonuç olarak; yapılan bu
çalışmada kullanılan tanenler bitki hastalık etmenlerine karşı kullanılan
sentetik bileşiklere alternatif olarak kullanılabileceği saptanmıştır.
In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey
Authors: KESER Serhat , KESER Fatma , TURKOGLU İsmail , KAYGILI Omer , TEKIN Suat , DEMIR Ersin , KARATEPE Mustafa , YILMAZ Okkes , KIRBAG Sevda , SANDAL Suleyman , TURKOGLU Semra
Published: November 2019

Centaurea L.
species were used as medicinal plants among the people for treatment of the
common cold, abscesses, peptic ulcers, hemorrhoid and diabetes etc.. In the
present study, antiradical properties, phytochemical contents, antimicrobial
and antiproliferative activities of three Centaurea
species
were investigated. Centaurea
saligna (K.Koch) Wagenitz methanol
(99.94%), Centaurea virgata Lam. methanol (98.23%) and water
(98.10%) extracts were showed higher ABTS scavenging than trolox (96.79%). Centaurea kurdica Reichardt extracts
showed lower activity than trolox for all the antiradical assays. Centaurea
extracts exhibited antimicrobial activity against to some microorganisms. It
was determined that these Centaurea
species contain high amount of total flavonoid, phenolic and proanthocyanidin,
phenolic acids, phytosterols and unsaturated fatty acids. Also, three Centaurea extracts showed very high antiproliferative
property on LNCaP, HCT-116, MCF-7 cancer cell lines.
Estilos de liderazgo y satisfacción laboral en personal operativo en seguridad privada. Perspectiva psicosocial intralaboral
Authors: NIÑO ABELLA LINA ISABEL , PARRA OSORIO LILIANA
Published: November 2019

La Satisfacción Laboral y el Liderazgo han sido variables estudiadas en diversos sectores del mercado laboral. Asimismo, el dominio características de Liderazgo es una dimensión de factores psicosociales intralaborales. Cuyo objetivo fue determinar la relación entre los estilos de Liderazgo y niveles de Satisfacción Laboral en personal operativo en una empresa de vigilancia y seguridad privada en Cali, 2018. Estrategia metodológica: estudio cuantitativo, descriptivo correlacional de corte transversal, con una muestra aleatoria al azar de representación estadística de 147 guardas de seguridad. En cuanto a los cargos de supervisión se tomó la totalidad de la población (36 jefes de primera línea). Se aplicaron tres cuestionarios: ficha de datos generales del Ministerio de la Protección Social, de Satisfacción Laboral S20/23 y cuestionario multifactorial de Liderazgo (MLQ).

Resultados: El estilo de Liderazgo predominante fue el transformacional (44.3 %), seguido del transaccional (37.7 %). Existe correlación entre el Liderazgo Transformacional y la Satisfacción Laboral fueron: satisfacción laboral general (0.461), satisfacción con la supervisión (0.656), satisfacción con las prestaciones recibidas (0.595) y satisfacción con la participación (0.656). Conclusiones: El estilo de Liderazgo participativo, carismático y transformador es un aspecto determinante en la Satisfacción Laboral. Asimismo, las relaciones interpersonales sostenidas con los compañeros y superiores y los estilos de Liderazgo adecuados son factores protectores psicosociales si son percibidos como positivos dentro de la dinámica organizacional específicamente en la población de estudio (guardas de seguridad).
Conflict analysis: some theoretical and ethical considerations
Authors: MEDINA GUTIÉRREZ FERNANDO A.
Published: November 2019

Hope for development seems to be weathering. In recent years, research on development issues and developmental strategies has been replaced by a burgeoning literature on conflict analysis, conflict transformation and peace building. As the World is confronted with the catastrophic effects of free trade and open financial markets globalization –a catastrophe in terms of quality of life for the majority of the people, as well as in terms of social, gender and economic equality and environmental sustainability– we all are defied by the urgent need to make sense of this state of widespread political violence, Human Rights violations and massive international migration.

The purpose of this work is to consider some ethical, theoretical and methodological issues about conducting research on conflict, and especially when dealing with the victims and their attempt to have their voices heard, and to move from victimization to social agency.

In part one we give some consideration to the impact of contemporary violence and its manifestations. The second part reviews some of the most influential theories on political violence. The last part deals with some ethical and methodological challenges that stem from the task.
La doble realidad: arquitecto de sueños, demoledor de realidades: radiografía al artículo 199, Ley 1098 de 2006 a la luz de la psicología jurídica. Estudio de caso: feminicidio de Yuliana Samboní
Authors: VÁSQUEZ BOHÓRQUEZ FABIOLA
Published: November 2019

El momento en que un prestigioso arquitecto Bogotano se convierte en uno de los mayores referentes de crueldad y tortura en Colombia, da lugar a un punto de quiebre en los patrones de abuso sexual y feminicidio en el país. De allí surge un cuestionamiento a la efectividad de las leyes que protegen a la niñez colombiana, por ello la presente investigación pretende Analizar desde el lente de la psicología jurídica la efectividad del Artículo 199 de la Ley 1098 de 2006 –Ley de Infancia y Adolescencia– en materia de garantía de derechos a las niñas en Colombia a la luz de las cifras registradas durante el periodo 2006 a 2018 en materia de abuso sexual infantil en el país y el feminicidio de Yuliana Andrea Samboní Muñoz como exponente de una nueva tipología dentro de este delito.

De allí se concluye en razón al análisis y articulación de la psicología del testimonio, las personalidades psicopáticas, específicamente la personalidad compulsiva en su tinte psicótico y la efectividad de las penas privativas de la libertad ante personas que ostentan dicha tipología, que es necesario implementar estrategias preventivas que permitan que la sociedad tome conciencia de la existencia de perfiles como el de Rafael Uribe Noguera, un profesional prestigioso sin necesidad aparente de delinquir, pero con un desorden mental que así se lo exige.
Design of experiments for verification of computational life prediction methods
Authors: Samsonova O. V. , Fetisov K. V. , Karpman I. V. , Burtseva I. V.
Published: November 2019

The failure of heavily loaded rotating parts of aviation gas turbine engines may bring about dangerous consequences. The life of such parts is limited with the use of computational and experimental methods. Computational life prediction methods that are used without carrying out life-cycle tests of engine parts or assemblies should be substantiated experimentally. The best option for verifying the computational methods is to use the results of cyclic tests of model disks. These tests make it possible to reproduce loading conditions and surface conditions that correspond to those of real disks, and the data on the load history and material properties make it possible to simulate stress-strain behavior of disks under test conditions by calculation. This paper shows the process of planning such tests. It is assumed that the tests will be carried out in two stages - before and after the initiation of a low-cycle fatigue crack. A number of criteria are formulated that the geometry of model disks and their loading conditions are to satisfy. Based on these criteria, model disks were designed and the conditions for their testing were selected.
Methods of validation of the ballistic structure of space surveillance system orbital segment
Authors: Fadin I. A. , Yanov S. V. , Samokhvalov O. A.
Published: November 2019

Space activity brought about the space debris problem that constitutes a threat to active spacecraft. Nowadays the most efficient way of spacecraft protection against space debris is choosing the appropriate orbit parameters to prevent collisions of space objects. To do this one should know the parameters of motion of space objects (SO). At present the task of determining SO orbit parameters is solved be means of the space surveillance system (SSS). The Russian space surveillance system includes only ground based facilities located on the territory of the Russian Federation and Tajikistan. This fact does not allow determining the parameters of SO motion over the Western and Southern Hemispheres. The task of monitoring SO in low orbits (up to 2000km height) is of particular importance because there have already been collisions that generated a lot of debris which, in their turn, pose a new threat to Russian active spacecraft. To prevent prospective threats to the Russian orbital constellation associated with possible generation of new debris as a result of impacts or spontaneous separation (because of an explosion, for instance) of active SOs the parameters of motion of newly emerging space objects need to be determined quickly and efficiently. We propose to solve the task of online monitoring of space object motion by creating an orbital segment of SSS. The creation of the new system is to be preceded by the development of scientific methods for justification of its ballistic structure. This article presents a method based on the solution of an optimization task, where the target function is the dependence of the required number of measurer spacecraft on the quality indicators of space surveillance.
Solitary Fibrous Tumor of the Female Pelvis – Clues to the Radiological Diagnosis
Authors: Tereso Andreia , Oliveira João , Cunha Teresa Margarida
Published: November 2019

Solitary fibrous tumors were initially described in the pleural cavity and they were thought to have mesothelial origin. Nowadays, these tumors are known to have origin in the mesenchymal cells and they are ubiquitous with both pleural and extrapleural distribution. There are many extrapleural localizations, being the pelvis one of the rarest and the most challenging to diagnose. Usually, solitary fibrous tumors are clinically insidious and manifest as a slow-growing large tumor. At imaging, these tumors have different characteristics, and computed tomography and magnetic resonance play an important role in their diagnosis. Solitary fibrous tumors appear as heterogeneous enhancement on contrast-enhanced computed tomography, intermediate signal on T1-weighted images, hypointense on T2-weightes images and show intense heterogeneous enhancement in dynamic sequences. When they appear in the female pelvis, it is essential to recognize their radiological characteristics, in order to differentiate it from others tumors, like pure stromal ovarian tumors or Brenner tumors. This study reviews the female pelvis solitary fibrous tumors’ imaging findings and its differential characteristics from more common tumors, by describing illustrative confirmed cases.
Correlation of ACTH and Salivary Cortisol levels to diagnose Adrenal Insufficiency in cirrhotic patients.
Authors: Memon Dr Haris , Mujtaba Memon Dr. Muhammad Haroon , Shahab Dr. Mahum , Iqbal Dr. Mahmood , Memon Dr. Ghulam Murtaza
Published: November 2019

Purpose. The prevalence of adrenal insufficiency (AI) in patients with decompensated liver cirrhosis is unknown. Because these patients have lower levels of cortisol-binding carrier proteins, their total serum cortisol (TSC) correlates poorly with free serum cortisol (FC). Salivary cortisol (SaC) correlates better with FC. We aimed to establish SaC thresholds for AI for the 250 g intravenous ACTH test and to estimate the prevalence of AI in non-critically ill cirrhotic patients. Methods. We included 39 patients with decompensated cirrhosis, 39 patients with known AI, and 45 healthy volunteers. After subjects fasted ≥8 hours, serum and saliva samples were collected for determinations of TSC and SaC at baseline 0’ (T0) and at 30-minute intervals after intravenous administration of 250
Learning outcome of the Thai qualifications framework for higher education (2009) by PBL
Authors: Charupash Rujee
Published: November 2019

A classroom action research, the objective of which is to study five aspects of learning outcomes, as follows: 1) Ethics and Morals 2) Knowledge 3) Cognitive Skills 4) Interpersonal Skills and Responsibility 5) Numerical, Communication and Information Technology Skillsand to study the attitude towards Problem-Based Learning method (PBL). Purposive sampling selected a sample of 53 students from the first-year of dental nurses studying the Contemporary World Affairs subject. Data were collected using questionnaires (the evaluating tools on TQF: HEd) and were analysed by finding percentages and means. 1. Both lecturers and students found that the students were learning at an effective rate which was more than standard scores (60%) in five aspects: 1. Ethics and Morals (96.98%), 2. Knowledge (96.06%), 3. Cognitive Skills (94.33%), 4. Interpersonal Skills and Responsibility (96.73%) and 5. Numerical, Communication and Information Technology Skills (94.33%). 2. It was found that 100% of students have a positive attitude towards PBL.

Keywords: Learning outcomes, TQF, PBL.
Mutagénesis dirigida del conector interdominio ácido FVIIIa3 del factor VIII de la coagulación como estrategia para favorecer la cristalización de sus complejos con la trombina
Authors: Rojas-Murcia Jeremy , Arce-Solano Silvia , Fuentes-Prior Pablo , Hernández-Carvajal Erick
Published: November 2019

Las enfermedades cardiovasculares representan una de las principales causas de morbilidad y mortalidad a nivel mundial, lo que se traduce en un fuerte impacto económico en el sector salud. El factor VIII (FVIII) es un cofactor esencial en los procesos hemostáticos que participa en la formación del coágulo ante alguna señal de daño vascular. La proteasa trombina es el principal activador fisiológico del FVIII, pero los mecanismos moleculares de reconocimiento del FVIII por la trombina y la formación de los complejos transitorios Michaelis-Menten correspondientes aún no se han descrito en detalle. La cristalografía de rayos X es una técnica que permite resolver la estructura 3D de complejos proteicos, pero requiere la cristalización previa de la muestra a estudiar. Con el objetivo de favorecer la formación de cristales del FVIIIa3 humano (residuos Glu1649-Arg1689) acomplejado con la trombina, se realizó mutagénesis dirigida para generar los doble-mutantes FVIIIa3 (R1689Q, G1690P) y FVIIIa3 (R1689G, G1690P). Estos fragmentos fueron sobreexpresados de forma heteróloga y purificados, obteniendo rendimientos de ~1.5 mg por cada litro de cultivo bacteriano. Esto permitió generar los complejos proteicos FVIIIa3 (R1689Q, G1690P)•trombina y FVIIIa3 (R1689G, G1690P)•trombina en cantidades suficientes para explorar sus espacios de solubilidad de forma extensiva. En total, en cada caso se evaluaron entre 630 y 820 condiciones de cristalización distintas. A partir de esta búsqueda inicial se obtuvo algún tipo de precipitado cristalino en 22 condiciones, 10 de las cuales lograron ser optimizadas para obtener monocristales de alta calidad para posteriores ensayos de difracción con rayos X.
Comprendiendo a los mejores estudiantes. Una mirada más allá de la docencia
Authors: Rubinsztejn Goldfarb Gustavo , Grijalvo Martín Mercedes , Rivera-Torres Pilar , Araújo Cazeres Luis
Published: November 2019

Se ha demostrado que la intención de los estudiantes de recomendar su universidad está influida positivamente por su percepción de la calidad global que experimentan en el servicio universitario. Sin embargo, no está claro cuáles son las dimensiones de la calidad que más impactan en esa percepción ni cómo estas evolucionan en el tiempo para el mismo estudiante. Esta investigación pretende llenar ese vacío, utilizando medidas de calidad docente y del servicio integradas con medidas de la experiencia de los estudiantes y de su percepción de la calidad global de la carrera. El estudio utiliza modelos de ecuaciones estructurales con datos secundarios de los registros de la encuesta de calidad continua de la Universidad ORT Uruguay que siguen a 232 mejores estudiantes durante toda su experiencia con la universidad, con un total de 1681 registros. Los resultados muestran que la importancia relativa de la calidad docente y la calidad del servicio en la percepción de la calidad global evolucionan con el tiempo para los mejores estudiantes. La calidad docente es más importante en las etapas iniciales mientras que en las etapas avanzadas la calidad del servicio se vuelve más importante. Asimismo la evidencia sugiere que la etapa de la experiencia del estudiante no modera el efecto positivo de la percepción de la calidad global en la intención de recomendar. Estos resultados son de gran importancia para los responsables de las políticas universitarias. La intención de recomendar puede mejorar si la calidad docente y de los servicios está diseñada específicamente para cada etapa de la experiencia del estudiante. Esto es particularmente importante en las etapas finales, cuando los estudiantes están a punto de terminar sus estudios. Las instituciones de educación superior pueden mejorar su proceso de planificación estratégica al incluir la segmentación de los estudiantes según su experiencia.
Formación afectiva en la educación parvularia de Chile
Authors: Mujica Johnson Felipe , Toro Oyarzún Maritza Angélica
Published: November 2019

El currículum de educación preescolar en Chile propone una educación integral del alumnado, por tanto el currículo de este ciclo educativo contiene diferentes objetivos de aprendizaje afectivo que refieren a las emociones, las actitudes o los intereses del alumnado. Entre los antecedentes teóricos del tema destaca una propuesta basada en la teoría del bienestar subjetivo. Sin embargo, la formación afectiva requiere también ser integrada a la educación moral. Por esa razón la finalidad de este estudio es analizar los objetivos de aprendizaje del ámbito afectivo en el currículo de educación parvularia de Chile en función de la formación moral del alumnado. La metodología responde al enfoque cualitativo, con un diseño de estudio documental, de modo que se analizaron todos los objetivos de aprendizaje del currículo preescolar. Los datos fueron sometidos a un análisis de contenido deductivo-inductivo, con la utilización del programa Atlas.ti versión 7.5. Los resultados indican que existen objetivos de aprendizaje del ámbito afectivo planteados desde una perspectiva abierta y contextualizada que favorecen una comprensión crítica de la afectividad. Así, se plantean aprendizajes coherentes tanto con una educación emocional situada y flexible como con los intereses personales. Desde esta perspectiva se acepta con normalidad el afecto tanto positivo como negativo para el bienestar subjetivo. Pero también existen objetivos que responden a una perspectiva cerrada y estandarizada en la que solo se promueve el afecto positivo para el bienestar subjetivo, desconociendo la función del afecto negativo para el bienestar subjetivo o la posibilidad de percibir afectos diferentes a los que propone el currículum. Finalmente, se concluye que el currículo exige al alumnado preescolar experimentar emociones positivas para el bienestar subjetivo ante ciertos contenidos curriculares, ignorando que en esencia las emociones no se aprenden porque son respuestas ante ciertos aprendizajes de diferentes ámbitos, como el de la formación moral.
Repeated Police Mental Health Act Detentions in England and Wales: Trauma and Recurrent Suicidality
Authors: Warrington Claire
Published: November 2019

Most police Mental Health Act (Section 136) detentions in England and Wales relate to suicide prevention. Despite attempts to reduce detention rates, numbers have risen almost continually. Although Section 136 has been subject to much academic and public policy scrutiny, the topic of individuals being detained on multiple occasions remains under-researched and thus poorly understood. A mixed methods study combined six in-depth interviews with people who had experienced numerous suicidal crises and police intervention, with detailed police and mental health records. A national police survey provided wider context. Consultants with lived experience of complex mental health problems jointly analysed interviews. Repeated detention is a nationally recognised issue. In South East England it almost exclusively relates to suicide or self-harm and accounts for a third of all detentions. Females are detained with the highest frequencies. The qualitative accounts revealed complex histories of unresolved trauma that had catastrophically damaged interviewee’s relational foundations, rendering them disenfranchised from services and consigned to relying on police intervention in repeated suicidal crises. A model is proposed that offers a way to conceptualise the phenomenon of repeated detention, highlighting that long-term solutions to sustain change are imperative, as reactive-only responses can perpetuate crisis cycles.
3D Printed Lab-on-a-Chip Diagnostic Systems - Developing a Safe-by-Design Manufacturing Approach
Authors: Karayannis Panagiotis , Petrakli Fotini , Gkika Anastasia , Koumoulos Elias
Published: November 2019

The aim of this study is to provide a detailed strategy for Safe-by-Design (SbD) 3D printed lab-on-a-chip (LOC) device manufacturing, using Fused Filament Fabrication (FFF) technology. At first, the applicability of FFF in lab-on-a-chip device development is briefly discussed. Subsequently, a methodology to categorize, identify and implement SbD measures for FFF is suggested. Furthermore, the most crucial health risks involved in FFF processes are examined, placing the focus on the examination of ultrafine particle (UFP) and Volatile Organic Compound (VOC) emission hazards. Thus, a SbD scheme for lab-on-a-chip manufacturing is provided, while also taking into account process optimization for obtaining satisfactory printed LOC quality. This work can serve as a guideline for the effective application of FFF technology for lab-on-a-chip manufacturing through the safest applicable way, towards a continuous effort to support sustainable development of lab-on-a-chip devices through cost-effective means.
Two-Phase Flow Characteristics on The Extensive Expansion Channel
Authors: Wibawanto Latif Ngudi , Santoso Budi , Juwana Wibawa Endra
Published: November 2019

This research was conducted to find out the flow characteristic of two phases through channel with sudden expansion in the form of change of flow pattern and pressure recovery. The test was conducted with variation of superficial velocity of water 0.2-1.3 m / s and superficial air velocity of 0.2-1.9 m / s resulting in pattern of three flow patterns ie bubble, plug, and slug. The expansion channel resulted in some changes to the flow pattern that originally plugs in the upstream channel into bubble in the downstream channel and the slug becomes plug. Pressure recovery experimental results were compared with the homogeneous model flow equation and Wadle correlation, the two correlations had predictions with standard deviation values of 0.32 and 0.43.
Karakteristisasi dan Profil Biodegradasi Material Biokomposit Bovine Hidroksiapatit (Bha)/Ampas Kopi/Shellac
Authors: Hidayat Taufiq , Triyono Joko , Masykur Abu
Published: November 2019

The incidence of fractures in Indonesia is quite high so it needs biomaterials in the field of health that is economical and environmentally friendly. Bovine bone waste can be used for grafting, repairing, replenishing or replacing bones and restoring dental tissue. The purpose of this research is to determine whether the content of the coffee grounds and shellac will disappear after the sintering process, and how the effects of coffee grounds on the porosity and degradation rate of BHA biocomposite materials. This research uses heating method of calcination and sintering. Based on the analysis of test data conducted, it was concluded that SEM EDX observation shows the presence of inorganic elements of Ca and P with high intensity and Na, Mg, O and C with low intensity. Observation of XRD diffraction pattern shows 2θ values of the sample according to the standard diffraction pattern of HA JCPDS 9-432. FTIR functional group analysis showed no major peak points other than phosphate functional groups ( ), carbonates ( ) and hydroxyl (OH-). From these three observations indicate that the content of coffee and shellac dregs has disappeared completely when the sintering process and leaving only the content of BHA and the more mixture of coffee dregs used will decrease the density value and increase the number of porus and accelerate the degradation rate.
STUDI EKSPERIMENTAL PERPINDAHAN KALOR KONVEKSI, PENURUNAN TEKANAN DAN FAKTOR GESEKAN PADA ALAT PENUKAR KALOR MENGGUNAKAN MICRO-FIN TUBE
Authors: Rifa’i Ahmad Imam , Kristiawan Budi , Wijayanta Agung Tri
Published: November 2019

Micro-fin is the popular technique for increasing heat transfer performance of the heat exchangers. In this research, the heat transfer coefficient of water inside counter-flow heat exchangers with micro-fin was investigated by experiment at the Reynolds number (Re) was varied from 4000-10,000. The results show that the heat transfer coefficient increase with increasing Reynolds number. Furthermore, effect helical micro-fin increasing pressure drop and friction factor at turbulent flow region.
DIAGNOSA KERUSAKAN BANTALAN BOLA MENGGUNAKAN METODE SUPPORT VECTOR MACHINE
Authors: Fathurrohman Muhammad , Lambang G. H R. Lulus , Susilo Didik Djoko
Published: November 2019

Bearings are the critical part of any rotating machine. The catastrophic failure of the bearing can lead to fatal and harmful to the operation of the machine. Therefore, predictive maintenance based on condition monitoring of bearing is very important. The objective of this research is to apply Support Vector Machine (SVM) method for fault diagnosis of the ball bearing. The research was carried out at the bearing test rig. Four types of ball bearing condition, such as normal, inner race defect, ball defect, and outer race defect were measured of the vibration signals using data acquisition with a sampling frequency of 20 kHz at the constant speed of 1400 RPM. Various features were extracted from vibration signals in time domain, such as RMS, variance, standard deviation, crest factor, shape factor, skewness, kurtosis, log energy entropy and sure entropy. PCA transformation was employed to reduce the dimension of feature extracted data. SVM classification problems were solved using MATLAB 2016a. The results showed that the application of RBF kernel function with the C parameter =1 was the best configuration. The training model accuracy was 98.93% and the testing accuracy of SVM was 97.5%. Finally, the research results show that the SVM classification method can be used to diagnose the fault condition of the ball bearing..
Clinical Characteristics Other Than Intralesional Hyperdensity May Increase the Preoperative Diagnostic Accuracy of Maxillary Sinus Fungal Ball
Authors: Cha Hyunkyung , Song Yoonjae , Bae Yun Jung , Won Tae-Bin , Kim Jeong-Whun , Cho Sung-Woo , Rhee Chae-Seo
Published: November 2019

Objectives. This study aimed to evaluate the clinical characteristics of maxillary sinus fungus ball (MFB) to increase the preoperative diagnostic accuracy.Methods. A retrospective review of 247 patients who underwent endoscopic sinus surgery for unilateral maxillary sinusitis from January 2015 to December 2017 at a single institution was performed. Patients with pathologically proven MFB were compared to those with unilateral chronic maxillary sinusitis (CMS). Patient demographics and computed tomography (CT) findings were evaluated. The CT features were categorized as intralesional hyperdensity (calcification), the irregular lobulated protruding lesion (fuzzy appearance), maxillary sinus full haziness without mass effect, maxillary sinus full haziness with mass effect, and others. A regression tree analysis was performed.Results. In total, 247 patients were analyzed; among them, 179 (72.5%) had MFB and 68 (27.5%) had CMS. MFB showed predominance in older individuals. Among the radiological features, intralesional hyperdensity was most commonly associated with MFB. The presence of a fuzzy appearance or full opacity with mass effect was also associated with MFB. The highest area under the curve was noted with the regression tree analysis based on the model, which included the presence of intralesional hyperdensity, demographic data (age), and presence of fuzzy appearance or maxillary sinus full haziness with mass effect in case of absence of intralesional hyperdensity (0.904).Conclusion. A simple algorithm to optimize the preoperative diagnosis of MFB was developed. Physicians should be aware of such findings in the management of patients presenting with unilateral CMS.
PENGEMBANGAN E-MODUL BERBASIS INKUIRI UNTUK PEMBELAJARAN GEOMETRI PADA PROGRAM STUDI PGSD
Authors: Suastika I Ketut , Triwahyuningtyas Dyah
Published: November 2019

Tujuan penelitian ini adalah untuk mengembangkan e-modul berbasis inkuiri untuk matakuliah Pembelajaran Geometri pada Program Studi Pendidikan Guru Sekolah Dasar (PGSD).  Tahapan pengembangan yang digunakan dalam penelitian ini adalah tahapan pengembangan Plomp meliputi: investigasi awal, prototipe, dan asesmen. Pada tulisan ini, peneliti hanya fokus pada pemaparan hasil dari investigasi awal. Investigasi awal dilakukan pada prodi PGSD di kampus yang berafiliasi PGRI di Jawa Timur. Hasil yang diperoleh pada investigasi awal: (1) materi yang disajikan pada pembelajaran geometri meliputi materi bangun datar dan materi bangun ruang, (2) pembelajaran yang dilaksanakan didominasi oleh dosen, (3) ada bahan ajar yang digunakan sebagai pegangan, namun masih belum menggunakan e-modul, (4) bahan ajar yang digunakan masih belum memberikan porsi yang cukup untuk mahasiswa menemukan konsep.
Users’ Perception of the Hospital Information System in a Maternity Hospital in Lampung, Indonesia
Authors: Asyary Al , Prasetyo Arief Kurniawan Nur , Eryando Tris , Gerke Solvay
Published: November 2019

Hospital information systems (HIS) have been applied on a massive scale; however, user evaluation of their effectiveness, efficiency, and service quality improvements remain rare. This study aimed to describe the utility of information systems from the users’ point of view by using the Technology Acceptance Model (TAM) in a maternity hospital in Lampung, Indonesia. The study provided an overview of the features of the information system and the workflow of the user through this information system. Screenshots were taken by using Camtasia Studio 2.0 Trial Version application software for one day (two shifts) in the outpatient service. The HIS generally supported the workflow, but not all application modules were fully applied. The obstacles appear to be at the registration unit/outpatient registration and queue dashboard, cashier unit, pharmacy unit, medicine storage/room, and poly unit/checking room. A TAM framework, which included perceived ease of use and perceived usefulness of the information system, revealed that the currently implemented HIS was not perceived as optimal. However, users are still optimistic and aware of the usefulness of the information system in supporting their jobs. Thus, leaders have committed to initiate the potential development of this information system in the inpatient polyclinic.
Midwife’s Role in the Mother-to-Child Transmission Prevention Program in Primary Health Care in Yogyakarta
Authors: Meilani Niken , Setiyawati Nanik , Barasa Sammy Onyapidi
Published: November 2019

Curing and eradicating Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) are to the core principles of the United Nations’ Sustainable Development Goals (SDGs). The incidence of HIV in the world remains high. Although midwives play a pivotal role in PMTCT implementation, the factors associated with midwives’ role in its implementation are not well understood. The aim of this study was to determine factors associated with midwives’ role in implementation of PMTCT. This study used a cross-sectional design. The subjects were 80 midwives at 14 primary health care in Yogyakarta City, Indonesia. The study was conducted from April to August 2017. Data were analyzed through univariate, bivariate with chi-square and Fisher’s exact test, multivariate with logistic regression. The results showed that 47.5% of midwives were in the poor category regarding implementation of PMTCT. Information availability through socialization (p-value = 0.047) and knowledge level (p-value = 0.016) were found to be related to PMTCT implementation. There was no relationship between age, length of work, education level, marital status, availability of information, midwife’s attitude, perception of the availability of facilities and institutional support with midwife behavior in PMTCT implementation. Multivariate analysis showed that level of knowledge was the most dominant factor affecting PMTCT implementation (OR:6.2; CI 95% = 1.8-21.4). We recommend that efforts should be made to continuously improve the knowledge of midwives on PMTCT implementation through peer support and training in order to achieve sustainable development goals.
Overweight and Obesity Status with Dental Caries among Children Aged 7–12 Years Old in Badung District, Bali 2018
Authors: Machmud Putri Bungsu , Rafitha Hariani , Djuwita Ratna , Gayatri Dwi , Ariani Ayub Fakhrana
Published: November 2019

Dental caries is an infectious disease that Dental  is characterized by the dental damage resulting from microorganism products in carbohydrate fermentation. Dental caries and obesity in children are multifactorial diseases associated with eating habits and certain lifestyle factors. This study aimed to assess the association between overweightness, obesity, and dental caries among children aged 7–12 years in Badung district, Bali province in 2018. The total sample of 426 children and their mothers were recruited from all first to fifth elementary grade students in three schools selected by simple random sampling. The logistic regression analysis has demonstrated a significant association between obesity and dental caries (OR: 1.830; 95% CI: 1.230–2.722) and showed that after controlling for the confounding variables, obese children have a twice higher chance of experiencing dental caries than non-obese children. Therefore, strengthening the existing health education programs in schools, including those on healthy food or snack components, and improving the efficiency of physical activities for preventing obesity could be a short-term strategy to protect school children from childhood obesity and dental caries.
A Correlation for Estimating the Biot Coefficient
Authors: Li Qi , Aguilera Roberto , Cinco-Ley Heber
Published: November 2019

The objective of this paper is to develop an easy-to-use correlation for estimating the Biot coefficient. This is important because the Biot coefficient plays an important role in solving many practical petroleum-engineering problems, including, for example, the design of hydraulic-fracturing jobs and the estimation of in-situ closure stress on proppant.

The procedure for developing the proposed empirical correlation uses data from various lithologies including limestone, sandstone, shale, marble, and granite. Thus, the correlation has application in conventional and unconventional petroleum reservoirs. The use of the correlation requires knowledge of permeability and porosity, the data commonly available in petroleum engineering (on the other hand, the Biot coefficient data are almost never available). The ratios of permeability to porosity (commonly known as process or delivery speed) and pore-throat radii (rp35) are entered for estimating the Biot coefficient from the correlation proposed in this paper. The correlation is useful in those cases where sophisticated experimental work needed for estimating the Biot poroelastic coefficient is not available.

Testing against various data sets indicates that the proposed correlation provides reasonable results. In the past, methods with different complexity levels have been used for estimating the Biot coefficient. These have included, for example, (1) a method that requires the knowledge of bulk modulus of the rock mineral and bulk modulus of the skeleton with no fluids in it, parameters that are not usually available for petroleum reservoirs; (2) a method that is based on knowledge of only porosity; (3) a method that is based on the knowledge of only permeability; and (4) an approach that simply assumes that the Biot coefficient is equal to 1.0 or some other number. The proposed correlation falls somewhere in the middle. It is not as simple as saying that the Biot coefficient is equal to unity or saying that it depends only on porosity, or only on permeability. On the other hand, it is not as complex as requiring sophisticated laboratory work of the type mentioned in (1) above.

The novelty of this work is the development of an original easy-to-use correlation for estimating the Biot coefficient in conventional and unconventional (tight and shale) reservoirs on the basis of knowledge of the ratio of permeability to porosity (k/ϕ) and the pore-throat radius (rp35). The correlation is developed in such a way that it also has application for estimating the Biot coefficient in the case of unconsolidated petroleum reservoirs and oil sands. The overall approach allows the integration of geomechanics with flow units, geology, petrophysics, and reservoir engineering (RE).
Investigation of the Combined Effects of Temperature and Large-Scale Tortuosity on Friction-Factor Profile in Straight Inclined Sections
Authors: Wiktorski Ekaterina , Sui Dan , Khalifeh Mahmoud , Khatibi Milad
Published: November 2019

This paper studies the implicit effects of temperature and wellbore tortuosity on the mechanical friction factor in torque-and-drag models applied to straight inclined sections. Experimental work was performed to measure the variation of viscosity and density of a water-based-mud (WBM) sample with respect to temperature and pressure. The effect of wellbore tortuosity was accounted for by means of the dogleg-severity (DLS) filter, which is presented in the paper. Experimentally obtained parameters were included in an algorithm for friction-factor-profile back calculation using a selected torque-and-drag model. A field case is presented to show this approach. The calculated friction factors were compared with those obtained by using the original torque-and-drag model and the averaged friction-factor values provided by the field operator, and the deviation mechanisms were discussed. Comparing the obtained results, we concluded that pressure and temperature, accounted for through variation in fluid buoyancy with depth, affect friction factor just marginally for rotation off-bottom and negligibly for tripping operations. The unplanned large-scale tortuosity affects the ultimate friction factor more significantly. The magnitude of the studied effects would greatly depend on the wellbore conditions. By including additional parameters in the traditional torque-and-drag models, researchers and engineers would be able to evaluate the effects of these parameters on the friction-factor estimation. It can help to estimate the range of friction forces during the planning phase and explain abnormal trends in post-run analysis.
GWAS and co-expression network combination uncovers multigenes with close linkage effects on oleic acid content accumulation in Brassica napus
Authors: Qian Lunwen , Yao Min , Guan Mei , Zhang Zhenqian , Zhang Qiuping , Cui Yixin , Chen Hao , Liu Wei , Jan Habib U. , Voss-Fels Kai P. , Werner Christian R. , He Xin , Guan Chunyun , Liu Zhongsong , Snowdon Rod J. , Hua Wei
Published: November 2019

Abstract Background: Strong artificial and natural selection causes the formation of highly conserved haplotypes that harbor agronomically important genes. GWAS in combination with haplotype analysis has evolved as an effective method to dissect the genetic architecture of complex traits in crop species. Results: We used the 60K Brassica Infinium SNP array to perform a genome-wide analysis of haplotype blocks associated with oleic acid (C18:1) in rapeseed. Six haplotype regions were identified as significantly associated with oleic acid (C18:1) that mapped to chromosomes A02, A07, A08, C01, C02 and C03. Additionally, whole-genome sequencing of 50 rapeseed lines revealed three genes (BnmtACP2-A02, BnABCI13-A02 and BnECI1-A02) in the A02 chromosome haplotype region and two genes (BnFAD8-C02 and BnSDP1-C02) in the C02 chromosome haplotype region that were closely linked to oleic acid content phenotypic variation. Moreover, the co-expression network analysis uncovered candidate genes from these two different haplotype regions with potential regulatory interrelationships with oleic acid content accumulation. Conclusions: Our results suggest that several candidate genes are closely linked, which provides us with an opportunity to develop functional haplotype markers for the improvement of the oleic acid content in rapeseed.
Rapid identification and characterization of genetic loci for defective kernel in bread wheat
Authors: Fu Chao , Du Jiuyuan , Tian Xiuling , He Zhonghu , Fu Luping , Wang Yue , Xu Dengan , Xu Xiaoting , Xia Xianchun , Zhang Yan , Cao Shuanghe
Published: November 2019

Background Wheat is a momentous crop and feeds billions of people in the world. The improvement of wheat yield is very important to ensure world food security. Normal development of grain is the essential guarantee for wheat yield formation. The genetic study of grain phenotype and identification of key genes for grain filling are of great significance upon dissecting the molecular mechanism of wheat grain morphogenesis and yield potential. Results Here we identified a pair of defective kernel (Dek) isogenic lines, BL31 and BL33, with plump and shrunken mature grains, respectively, and constructed a genetic population from the BL31/BL33 cross. Ten chromosomes had higher frequency of polymorphic single nucleotide polymorphism (SNP) markers between BL31 and BL33 using Wheat660K chip. Totally 783 simple sequence repeat (SSR) markers were chosen from the above chromosomes and 15 of these were integrated into two linkage groups using the genetic population. Genetic mapping identified three QTL, QDek.caas-3BS.1, QDek.caas-3BS.2 and QDek.caas-4AL, explaining 14.78 - 18.17%, 16.61 - 21.83% and 19.08 - 28.19% of phenotypic variances, respectively. Additionally, five polymorphic SNPs from Wheat660K were successfully converted into cleaved amplified polymorphic sequence (CAPS) markers and enriched the target regions of the above QTL. Biochemical analyses revealed that BL33 has significantly higher grain sucrose contents at filling stages and lower mature grain starch contents than BL31, indicating that the Dek QTL may be involved in carbohydrate metabolism. As such, the candidate genes for each QTL were determined according to International Wheat Genome Sequence Consortium (IWGSC) RefSeq v1.0. Conclusions Overall, we achieved a rapid QTL mapping and reasonable predication of causal genes for Dek, laying foundation to conduct fine mapping and dissect the regulatory mechanism underlying Dek trait in wheat.