bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review on Polymeric Nanostructured Micelles for the Ocular
Inflammation-Main Emphasis on Uveitis
Authors: Kumar Manish , Kaushal Nikita , Singh Amanjot , Tiwari Abhishek , Tiwari Varsha , Pahwa Rakesh
Published: October 2022

Background:

Various types of nano-formulations are being developed and tested for the
delivery of the ocular drug. They also have anatomical and physiological limitations, such as tear
turnover, nasal lachrymal waste, reflex squinting, and visual static and dynamic hindrances, which
pose challenges and delay ocular drug permeation. As a result of these limitations, less than 5% of
the dose can reach the ocular tissues.

Objective:

The basic purpose of designing these formulations is that they provide prolonged retention
for a longer period and can also increase the course time.

Methods:

To address the aforementioned issues, many forms of polymeric micelles were developed.
Direct dissolving, dialysis, oil-in-water emulsion, solvent evaporation, co-solvent evaporation,
and freeze-drying are some of the methods used to make polymeric nano micelles.

Results:

Their stability is also very good and also possesses reversible drug loading capacity.
When the drug is given through the topical route, then it has very low ocular bioavailability.

Conclusion:

The definition and preparation process of polymeric micelles and anti-inflammatory
drugs used in uveitis and the relation between uveitis and micelles are illustrated in detail.
Pulegone: An Emerging Oxygenated Cyclic Monoterpene Ketone
Scaffold Delineating Synthesis, Chemical Reactivity, and Biological
potential
Authors: Chopra Bhawna , Dhingra Ashwani K.
Published: October 2022

Pulegone ((R)-5-Methyl-2-(1-methylethylidine) cyclohexanone) is a pharmacologically
active, natural monoterpene ketone obtained from leaves and flowering
tops of the mint family (Lamiaceae). The aim is to comprise the physicochemical and
biological aspects of pulegone. All significant databases were collected via electronic
search using Pubmed, Scopus, Web of Science, and Science Direct and were compiled.
This review presents the occurrence, chemistry, and modifications of pulegone structure
and its effect on the biological system. Pulegone represents various pharmacological
properties, i.e., antioxidant, antimicrobial, anti-feeding, antifungal, antiviral, and pesticide
activities, and has a significant role as an abortifacient and emmenagogue. Thus, this
present review concludes the knowledgeable erudition on pulegone that paves the way
for further work.
Expectations, Rejections, and Reviewer 2: Publishing Demystified
Authors: Lookingbill Valerie , Kitzie Vanessa , Winberry Joseph , Lund Brady , Colón-Aguirre Mónica , Hands Africa
Published: October 2022

Navigating the pressures and processes of academic publishing is a challenge for doctoral students and recent graduates. While there is a growing expectation that doctoral students and recent graduates are capable of immediately producing publishable research and survive in a “publish or perish” environment, many doctoral students have misperceptions of and remain uncertain about how to navigate the publishing process (Rich, 2013). However, while the quantity of publications does not necessarily equate to success in the job market, publishing productivity is critical in finding employment (Hatch & Skipper, 2016). As such, doctoral students need to consider the publishing process early in their program so they can present a competitive publishing record when entering the job market. Yet, many universities do not provide formal training on understanding scholarly publishing or devote efforts to include explicit content on navigating the publishing process (Hanafizadeh & Shaikh, 2021). This panel from ALISE’s Doctoral Student Special Interest Group will therefore address this gap by presenting advice and strategies for doctoral students at any stage of their program, focusing on expectations of publishing as a doctoral student and best practices for publishing research. Panelists, comprised of early-career faculty and doctoral candidates with admirable publication records, will discuss their experiences with publishing, specifically through discussions of (1) expectations for publishing productivity as a doctoral student; (2) their decision-making processes about where to submit research for publication; (3) their strategies for publishing most efficiently; and (4) their experiences with publication rejections. Panelists will provide insight into the typical workflows of the publishing process, detail the most common pitfalls when submitting research for publication, and describe how to effectively address these pitfalls in manuscripts to minimize chances of receiving rejections. Drawing on the experiences of the panelists, attendees will learn of best practices for submitting research for publication and understand how to address fundamental issues and pitfalls of publishing to help increase their chances of getting their work published. Attendees will be able to ask questions and/or share their own experiences after panelists present through a moderated Q&A. The session will proceed as follows: 

1. Welcome and introduction of panelists (5 minutes) 

2. Panelist presentations on key topics (60 minutes) 

3. Moderated Q&A (15 minutes) 

4. Concluding thoughts (10 minutes)
Informative Storytelling with Provenance Research Sources
Authors: Bartley Jane E. , Buchanan Sarah A.
Published: October 2022

Provenance has underpinned archival practice in America across the past century, guiding archivists in the arrangement, description, and accessioning of new and legacy collections. Provenance research is a necessary step taken to secure pending donations and title information, and ultimately tell the story of the object’s journey to the current possessor. Across four domains of key interest in the “Developing Extensible Methods for Provenance Research” project, we examine source-specific methods that are most useful to practitioners, and communicate them in an open educational resource (OER) meant to broaden access and awareness of provenance research among administrators and students engaging with collections. Our poster will demonstrate how archival workers seek and then combine information laboriously gathered from photographs, legal documents, and handwritten materials among other resources in creative, inventive, and engaging ways that invite visitors into stories that the objects – if only they are displayed – can tell about our shared pasts and futures. Such information sources can serve a multitude of stakeholder goals, e.g. employing datapoints about transfers and handoffs to encourage object-based learning, transparency, and accountability.
LIS Leadership: Opportunities and Barriers for People of Color
Authors: Singh Vandana , Cooke Nicole , Rorissa Abebe , Hands Africa , Knox Emily
Published: October 2022

Responding to the conference theme of “Go Back and Get It – From One Narrative to Many” this panel provides an opportunity for LIS faculty of color to voice their narratives about leadership opportunities in LIS. Through this panel, we will bring together people of color from different levels of LIS faculty (Assistant Professor, Associate Professor, and Professor) to discuss their expectations and experiences of opportunities and barriers in leadership positions in LIS. According to the latest ALISE Statistical report, 2021 (ALISE Statistical Report, 2021) – out of a total of 55 heads of schools in LIS, there are 34 white, 11 Asian, 2 Black, and 1 Native American and Hispanic. The representation of marginalized groups in LIS leadership remains minimal.

The panelists will discuss their experiences of being in leadership or administrative positions and the availability or lack of training and guidance for faculty of color. Panelists who have not been in leadership/administrative positions will discuss the hesitation and perceived barriers for this work. This panel will also create a platform for the faculty of color to assert their narrative, their interest, their ambitions, and their competence in leadership positions in LIS. Their stories with their reflections and illustrative examples will provide space for alternative narratives. Each panelist will give a 10 minute presentation and pose questions for audience engagement. Additionally, we will engage the audience to develop an agenda for future faculty leaders from marginalized groups. There will be a brainstorming and experience sharing session with the attending colleagues to discuss the following questions – What kind of barriers exist for POCs? How can we address these barriers? What are the systemic barriers that need to be removed by current leaders? What is the type of support that POC faculty needs to receive and succeed in leadership positions in LIS?

The panelists will solicit POC faculty to create a collaboration for developing leadership and administration training modules/toolkits for LIS faculty and doctoral students of color. This discussion will also explicate how this approach will be complementary to the current ALISE Leadership Academy. The goal is to spark dialogue between faculty and doctoral students of color to facilitate an equitable vision for the future. For the wider audience of the conference focused on the metaphorical meaning of Sankofa (ALISE 22 website), we hope that this discussion will provide a direction to “see” and “hear” the marginalized voices of people of color in LIS.
Educating for Equity
Authors: Villagran Michele , Hofman Darra
Published: October 2022

This poster presentation summarizes mixed-methods research from the 2021 ALISE Research Grant Competition Award: Educating for Equity?: Sexual and Gender Minority Privacy in Library and Information Studies Education. This project examined whether we can handle complex information policy questions by examining an urgent information problem facing libraries: the privacy of sexual and gender minority (SGM) individuals in the face of COVID-19 surveillance. This session aligns with the conference theme by illustrating how “privacy” is a polysemous concept. Information professionals grappling with privacy from a policy perspective must be prepared for its multi-faceted nature and the distinct privacy needs of different communities. SGM face significant information risks that differ from those of cis-gender, heterosexual people; improper information disclosure can lead to the loss of employment, housing, access to health care, and social support for SGM due to outing. This study asked, “Are LIS programs preparing their students to meet the needs of LGBTQ+ patrons and stakeholders from a policy perspective in the workplace?” Researchers conducted a mixed methods study that included a survey of LIS faculty, a content analysis of ALA-approved masters programs’ learning outcomes and syllabi, a document analysis of the privacy policies of a sample of libraries, and interviews with library employers. The researchers will share any results to date from their analysis and provide current best practices and recommendations for both libraries and LIS educators to help expand the understanding of the privacy of marginalized groups.
Many Narratives
Authors: McDowell Kate
Published: October 2022

Storytelling bridges a key epistemological divide in our field between socially constructed humanism of children’s story time and implicit positivist orientation of computational systems. Centering story and storytelling as fundamental to LIS calls for a richer variety of stories, tellers, and audiences for a future of greater inclusion.
Information Literacy is a Social Practice
Authors: Rath Logan
Published: October 2022

The field of information literacy (IL) suffers from a gap between theory and practice, meaning that librarians, as practitioners, do not adequately use and apply the theory of information science in their work (Hider et al., 2019; Julien et al., 2013; Nguyen & Hider, 2018). Specifically, IL is theorized as a social practice, yet practitioners appear to adopt a skills-based approach to IL. As an answer to this theory-to-practice gap, a grounded theory study found that seeing information literacy as a social practice is a threshold concept for academic instruction librarians. This dissertation study employed focus groups and semi structured solicited diary prompts to explore the fit of this threshold concept with the experiences of academic librarians.

The central research question for this study was: To what extent, if any, does the proposed threshold concept describe librarians’ beliefs about information literacy as a social practice? Qualitative content analysis of the focus group transcripts and the diary entries found that the threshold concept required a slight revision in order to accurately describe librarians’ beliefs about information literacy as a social practice. Where the initial version of the threshold concept had one arrow indicating "tensions" that prevent librarians from teaching IL as a social practice, the revised version contains an opposing arrow indicating "supports" that help librarians to deliver IL from a social practice standpoint. The role of skills and practices in IL instruction were investigated. Findings from this study have implications for LIS educators, library administrators, and practicing academic instruction librarians.
Reflections from MLS Students’ Perceptions of Information Literacy Modules – a SoTL Study
Authors: Hebert Holly , Reed Karen , Krahenbuhl Kevin
Published: October 2022

Bringing together graduate students from different backgrounds into an online MLS program means that they show up with varying degrees of skills and competences in information literacy when they first start. As LIS educators, we often have trouble knowing where to fit this instruction into our courses, or we hesitate to take valuable instruction time from other concepts since we believe students should already arrive with a good understanding of information literacy from their undergraduate experience. Although it’s often assumed that graduate MLS students already have a good handle on information literacy, in this researcher’s experience, this is not always the case. This qualitative study of students’ self-reflections during completion of information literacy modules looks at two semesters of data from our program’s core Librarianship course and are being approached as a scholarship of teaching and learning study through the lens of constructivism from an andragogical perspective. Common emerging are that students still experience research anxiety at this level and that gaps in schooling can leave students unsure of their current competency level. Results so far indicate that students are overall appreciative of the modules and that the knowledge gained and information literacy concepts from prior experience remembered is helpful to them. They report using these skills and competencies immediately during coursework and plan to use them in the future in their jobs and life.
Digital wonders
Authors: Urban Alex
Published: October 2022

How, if at all, does awe foster information seeking? This question was examined through a two-pronged approach. First, in a laboratory setting, participants (n = 34) were exposed to a variety of awe elicitors through a virtual reality (VR) head-mounted display. Participants’ quantitative and qualitative responses were gathered immediately after exposure in the laboratory as well as 24 hours later through questionnaires. Second, a stratified sample of participants who voluntarily conducted information seeking (n = 8) completed phenomenologically-informed interviews. Findings indicate that although awe is primarily experiential, information seeking may arise from surprising learners with unknown and unexplained phenomena. Additionally, feelings of perceptual envelopment and accessing the inaccessible characterized participants’ VR-based awe experiences. Emergent findings also reveal that creating awe-inspiring VR content may require reduced didactic information to generate feelings of presence. These findings point to ways that VR may increase learners’ intrinsic motivations for informal and formal research.
“No One Told Me”
Authors: Gross Melissa , Latham Don , Baum Brittany , Crabtree Lauren
Published: October 2022

Libraries are being called upon to assist with a variety of social problems including everything from housing and food insecurity to disaster recovery. In response, some public libraries have called on social workers to help. These developments beg the question of whether information professionals are being prepared for the realities of public library careers. This presentation reports findings from a series of 28 interviews with public librarians and branch managers to explore their views on how library and information science programs can ensure that students are prepared to respond to their community’s social service needs. Findings reveal that the inclusion of social work interview skills, de-escalation training, knowledge of social service resources, and instruction on how to collaborate with and supervise social workers would better prepare students for the realities of working in public libraries.
Discovery and Analytical Validation of a Vocal Biomarker to Monitor Anosmia and Ageusia in Patients With COVID-19: Cross-sectional Study
Authors: Higa Eduardo , Elbéji Abir , Zhang Lu , Fischer Aurélie , Aguayo Gloria A , Nazarov Petr V , Fagherazzi Guy
Published: October 2022

Background

The COVID-19 disease has multiple symptoms, with anosmia and ageusia being the most prevalent, varying from 75% to 95% and from 50% to 80% of infected patients, respectively. An automatic assessment tool for these symptoms will help monitor the disease in a fast and noninvasive manner.

Objective

We hypothesized that people with COVID-19 experiencing anosmia and ageusia had different voice features than those without such symptoms. Our objective was to develop an artificial intelligence pipeline to identify and internally validate a vocal biomarker of these symptoms for remotely monitoring them.

Methods

This study used population-based data. Participants were assessed daily through a web-based questionnaire and asked to register 2 different types of voice recordings. They were adults (aged >18 years) who were confirmed by a polymerase chain reaction test to be positive for COVID-19 in Luxembourg and met the inclusion criteria. Statistical methods such as recursive feature elimination for dimensionality reduction, multiple statistical learning methods, and hypothesis tests were used throughout this study. The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis) Prediction Model Development checklist was used to structure the research.

Results

This study included 259 participants. Younger (aged <35 years) and female participants showed higher rates of ageusia and anosmia. Participants were aged 41 (SD 13) years on average, and the data set was balanced for sex (female: 134/259, 51.7%; male: 125/259, 48.3%). The analyzed symptom was present in 94 (36.3%) out of 259 participants and in 450 (27.5%) out of 1636 audio recordings. In all, 2 machine learning models were built, one for Android and one for iOS devices, and both had high accuracy—88% for Android and 85% for iOS. The final biomarker was then calculated using these models and internally validated.

Conclusions

This study demonstrates that people with COVID-19 who have anosmia and ageusia have different voice features from those without these symptoms. Upon further validation, these vocal biomarkers could be nested in digital devices to improve symptom assessment in clinical practice and enhance the telemonitoring of COVID-19–related symptoms.

Trial Registration

Clinicaltrials.gov NCT04380987; https://clinicaltrials.gov/ct2/show/NCT04380987
Assessing the Content and Quality of Digital Tools for Managing Gestational Weight Gain: Systematic Search and Evaluation
Authors: Brammall Bonnie R , Garad Rhonda M , Boyle Jacqueline A , Hayman Melanie J , de Jersey Susan J , Teede Helena J , Hong Quoc V , Carrandi Alayna , Harrison Cheryce L
Published: October 2022

Background

Digital health resources have the potential to assist women in optimizing gestational weight gain (GWG) during pregnancy to improve maternal health outcomes.

Objective

In this study, we aimed to evaluate the quality and behavior change potential of publicly available digital tools (websites and apps) that facilitate GWG tracking.

Methods

Digital tools were identified using key search terms across website search engines and app stores and evaluated using the Mobile App Rating Scale, the App Behavior Change Scale, as well as criteria to evaluate the rigor and safety of GWG information.

Results

Overall, 1085 tools were screened for inclusion (162 websites and 923 apps), and 19 were deemed eligible. The mean Mobile App Rating Scale quality score was 3.31 (SD 0.53) out of 5, ranging from 2.26 to 4.39, and the mean App Behavior Change Scale score was 6 (SD 3.4) out of 21, ranging from 19 to 0. Of the 19 items used to evaluate rigor of GWG advice, most tools (n=11, 57.9%) contained ≤3 items.

Conclusions

This review emphasizes the substantial limitations in current digital resources promoting the monitoring and optimization of GWG. Most tools were of low quality, had minimal behavior change potential, and were potentially unsafe, with minimal linkage to evidence-based information or partnership with health care.
"АРМИЯ-2022" − САМОЕ МАСШТАБНОЕ КОНГРЕССНО-ВЫСТАВОЧНОЕ СОБЫТИЕ ГОДА
Authors: Набоких Л. , Попов С.
Published: October 2022

Международный военно-технический форум "Армия-2022", организатором которого выступает Министерство обороны России, состоялся уже в восьмой раз. Его центральные события проходили с 15 по 21 августа на традиционных площадках в Подмосковье: конгрессно-выставочном центре "Патриот" и на аэродроме Кубинка.
ИCТОЧНИКИ ОДИНОЧНЫХ ФОТОНОВ ДЛЯ ИНФОКОММУНИКАЦИОННЫХ СИСТЕМ
Authors: Зайцев А. , Зубилевич А. , Колесников О. , Коробов А.
Published: October 2022

Проанализировано современное состояние исследований в области создания источников одиночных фотонов для защищенных систем связи. Рассмотрены базовые платформы для создания источников одиночных фотонов, перспективные для применения в волоконно-оптических линиях связи и основные тенденции в развитии систем связи на основе технологии квантового распределения ключей. На основе анализа научной литературы выявлены пути развития технологий для создания перспективных источников одиночных фотонов, предназначенных для телекоммуникационных приложений.
Artículos científicos en las ciencias agrarias chilenas 1989 –2016: evolución, disciplinas e impacto liderado.
Authors: Padilla Navarro Patricio Andrés , Vallejos Romero Arturo
Published: October 2022

Se presentan los resultados de una investigación enmarcada en el campo de las ciencias agrarias en Chile, cuyo período comprendió de 1989 a 2016 donde se analizaron 5.873 artículos científicos relacionados a esta área científica. En la investigación se analizó, mediante indicadores bibliométricos de actividad científica, la evolución de la producción de artículos en las ciencias agrarias chilenas, la colaboración científica, las disciplinas mayormente trabajadas y el nivel de impacto normalizado liderado. Se concluyó la existencia de un sostenido aumento de artículos científicos en el período de estudio, la concentración temática en las disciplinas de ciencias veterinarias, pesquería y agronomía y recientes cambios en la estructura de colaboración científica con más participación internacional, especialmente de Estados Unidos.
Effects of Acupuncture with a Combination of GV20 and EX-HN1 Acupoints on CO2 Reactivity in the Anterior and Middle Cerebral Arteries during Hypercapnia in Normal Subjects: A Randomized Crossover Trial
Authors: Park Hojung , Moon Sang-Kwan , Lee Han-Gyul , Kwon Seungwon , Cho Seung-Yeon , Park Seong-Uk , Jung Woo-sang , Park Jung-Mi , Ko Chang-Nam , Cho Ki-Ho
Published: October 2022

Objectives: To investigate the effects of acupuncture at GV20 and EX-HN1 on cerebral blood flow (CBF) velocity and cerebrovascular reactivity (CVR) in the middle cerebral arteries (MCA) and anterior cerebral arteries (ACA) and to compare the effects to acupuncture at GV20.Methods: The study was a randomized, crossover trial that included 10 healthy men aged 20 to 29 years who underwent acupuncture treatment four times with a washout period of one week. The CBF velocity and CVR were measured by transcranial Doppler sonography (TCD) on both MCAs at the first and second visits, and both ACAs at the third and fourth visits. Participants were randomly assigned to one of two groups (A and B) before the first and third visits. Group A received two phases of acupuncture intervention at a single GV20 point and a combination of GV20 and EX-HN1 acupoints. Group B received the same interventions, but in the reverse order.Results: The increase in CO2 reactivity was significantly higher for the combination acupoints of GV20 and EX-HN1 than for the GV20 single acupoint in both MCAs (Right: 136 to 178, p=0.017; Left: 127 to 191, p=0.017) and ACAs (Right: 133 to 158, p=0.013; Left: 122 to 168, p=0.025). No significant change was noted in the corrected velocity at PETCO2 40 mmHg, blood pressure, or heart rate.Conclusions: The findings suggest that improvement of the CBF in the MCA and ACA after GV20 acupuncture increases when acupuncture is also performed at EX-HN1. These results clinically support the combined use of EX-HN1 and GV20 to treat disorders of MCA and ACA circulation.
CТ densitometry as an additional method in the diagnosis of pulmonary hypertension: a prospective study
Authors: Rakhimzhanova R. I. , Mardenkyzy D. , Dautov T. B. , Yelshibayeva E. S.
Published: October 2022

INTRODUCTION: This article presents the results of application of CT densitometry in the computed tomography (CT) of the chest to diagnose various forms of pulmonary hypertension.

OBJECTIVES: To determine the diagnostic value of CT densitometry using comparative analysis of lung tissue density in patients with various forms of pulmonary hypertension.

MATERIALS AND METHODS: The study included 528 patients diagnosed with pulmonary hypertension by means of right heart catheterization (RHC) of the National Research Cardiac Surgery Center, Republic of Kazakhstan. All patients were divided into 4 groups according to the classification of pulmonary hypertension of the World Health Organization (ESC/ERS Guidelines) from 2015. The first group included 254 patients with pulmonary hypertension pulmonary hypertension due to left heart disease (PHLHD). The second group included 210 patients with pulmonary arterial hypertension (PAH). The third group included 49 patients with chronic thromboembolic pulmonary hypertension (CTEPH). The fourth group — 15 patients with pulmonary hypertension due to respiratory disease (PHDRD). The mean age of the patients was 52.15±16.75 years. Contrast-enhanced chest CT imaging performed with a 64-slice multislice computed tomography system (Somatom Definition AS, Siemens) with post-processing to assess the lung tissue densitometric parameters, analyse the diameters of the pulmonary trunk and its main branches. The CT examination was carried in accordance with an «Embolism» protocol with intravenous administration of a contrast agent according to indications. Statistics: analysis was conducted using the Statistica 10 software. To quantitatively compare the two groups nonparametric Mann-Whitney test and the Kruskal-Wallace test were applied. Mean value and standard deviation in the format of «M±S» were used for quantitative parameters. Correlation analysis was carried out using Spearman’s nonparametric rank correlation.

RESULTS: In patients with severe pulmonary hypertension a tendency for fibrotic changes was most clearly observed in cases of pulmonary hypertension due to left heart disease (–809.92±26.52), and emphysematous changes in the pulmonary arterial hypertension group (–843.27±43.88).

CONCLUSION: CT lung densitometry should be performed in all patients with suspected pulmonary hypertension as an additional method of examination.
Magnetic resonance tomography of the lungs with paramagnetic contrast enhancement in dynamic follow-up control of treatment of lung cancer in radiophobic patient: a case report
Authors: Vorob’eva V. O. , Nudnov N. V. , Miller S. V. , Rodionov E. V. , Ussov W. Yu.
Published: October 2022

Till now the facilities of MRI with paramagnetic contrast enhancement (CE-MRI) in detection of lung tumors remain underused and almost ignored. A clinical case of primary detection and prospective follow-up of lung cancer in a patient whose MRI of the chest revealed a tumor lesion — a central cancer of the left lung, in particular a lesion of the bronchus of the lower lobe of the left lung. MRI of the chest with paramagnetic contrast enhancement was carried out as part of the whole body CE-MRI study after the complex therapy of breast cancer, and both the primary lung tumor and metastatic lesion of mediastinal — subbifurcation lymph nodes were revealed. With a transbronchial biopsy, the diagnosis of lung cancer was verified. Chemotherapy (ChT) was started using the vinorelbin/ carboplatin regimen. After this, the CE-MRI has been carried out during the whole period of followup of anti-cancer chemotherapy. At the CE-MRI during the first course of ChT visually the complete regression of the disease, also with clinical remission was achieved. However, the ChT scheme was not fully completed due to the patient’s departure for urgent private reasons. Two months later, the patient was examined again according to the same CE-MRI protocol, while a relapse of the disease was detected with a more pronounced lesion of the mediastinal lymph nodes than during the initial treatment. ChT with vinorelbine/carboplatin was again carried out under the control CE-MRI, this time completely. According to the chest CE-MRI, visual remission was achieved, with the disappearance of nodular tumor at the site of the previously identified primary tumor of lung cancer and metastatic lesions of lymph nodes. Thus, it was the CE-MRI which provided the early diagnosis and adequate control of treatment of the lung cancer with extensive local lymph nodes spread. After this CE-MRI, the whole body PET with 18F-fluorodeoxyglucose (FDG) was also performed and no signs of relapse or continued tumor growth were revealed. Five months after this stage, the patient did persist to stay completely preserved clinically, at work and socially active. Thus, the chest CE-MRI can be employed for the follow-up of the tumor process in lung cancer, as necessary, without radiation exposure, without limiting the number and frequency of studies.
Projected Least-Squares Quantum Process Tomography
Authors: Surawy-Stepney Trystan , Kahn Jonas , Kueng Richard , Guta Madalin
Published: October 2022

We propose and investigate a new method of quantum process tomography (QPT) which we call projected least squares (PLS). In short, PLS consists of first computing the least-squares estimator of the Choi matrix of an unknown channel, and subsequently projecting it onto the convex set of Choi matrices. We consider four experimental setups including direct QPT with Pauli eigenvectors as input and Pauli measurements, and ancilla-assisted QPT with mutually unbiased bases (MUB) measurements. In each case, we provide a closed form solution for the least-squares estimator of the Choi matrix. We propose a novel, two-step method for projecting these estimators onto the set of matrices representing physical quantum channels, and a fast numerical implementation in the form of the hyperplane intersection projection algorithm. We provide rigorous, non-asymptotic concentration bounds, sampling complexities and confidence regions for the Frobenius and trace-norm error of the estimators. For the Frobenius error, the bounds are linear in the rank of the Choi matrix, and for low ranks, they improve the error rates of the least squares estimator by a factor d2, where d is the system dimension. We illustrate the method with numerical experiments involving channels on systems with up to 7 qubits, and find that PLS has highly competitive accuracy and computational tractability.
Reducing food waste from social innovation perspective: a review of measures, research gaps and future directions
Authors: Zhao Guoqing , Liu Shaofeng , Wang Yi , Lopez Carmen , Ong Aira , Chen Xiaoning
Published: October 2022

Food waste (FW) has been increasingly recognized as a severe environmental, social, and economic problem. Therefore, it should be tackled innovatively by analyzing and synthesizing existing solutions. This study aims to achieve a comprehensive understanding of different social innovation measures adopted for reducing FW using a systematic literature review. After locating, collecting, evaluating, and analyzing 50 publications from four databases, we conclude that social innovation activities such as digital food-sharing platforms, social supermarkets, solidarity stores, and food rescue hubs are widely deployed in different FW reduction processes. Based on the findings, we synthesized several research gaps and proposed corresponding future research directions related to research methodology, country, food redistribution, food rescue, food donation, and food sharing. These directions include conducting research to develop suitable key performance indicators to evaluate the performance of digital food-sharing platforms, linking with specific theory to conduct empirical research on partnership analysis regarding social supermarkets, and investigating the structure of multiplex relations among different participants in the food rescue activities using social network analysis. We suggest that more keywords should be scrutinized and included when searching publications in future research as keyword selection is subjective.
Pneumocystis jirovecii pneumonia among pediatric inpatients before and after COVID-19 pandemic: molecular diagnosis, predisposing factors, and outcomes in Northeastern Iran
Authors: Hosseinikargar Neginsadat , Zarrinfar Hossein , seyedi seyed javad , Mehrad-Majd Hassan , Najafzadeh Mohammad Javad
Published: October 2022

Background:Pneumocystis pneumonia (PCP), caused by
P. jirovecii, is one of the opportunistic fungal infections that
can cause life-threatening pneumonia in children with underlying
diseases. Due to the similarity of the symptoms of PCP with other lung
infections, such as tuberculosis, differential and accurate diagnosis is
necessary. The current study investigated the molecular diagnosis of
P. jirovecii, predisposing factors, and the outcomes, among
pediatric inpatients in Northeastern Iran. Method: In this
study, 180 bronchoalveolar lavage (BAL) specimens were obtained from
hospitalized children with respiratory disorders. The specimens were
examined using Giemsa stain, and the genomic DNA was extracted according
to the protocol of the AmpliSens® kit. Real-time polymerase chain
reaction technique was used to detect P. jirovecii by the
AmpliSens Pneumocystis jirovecii ( carinii)-FRT PCR kit.
Results: Among the patients studied, 34 (18.9%) were positive,
and 8 (4.4%) were suspicious for the presence of P. jirovecii.
Among the 34 positive cases, 12 (35%) were related to before, and 22
(65%) were affected during the COVID-19 pandemic. Only 2 cases (5.88%)
of the positive cases detected by Real-time PCR method were observed
using Giemsa staining. Also, no correlation was observed between
positive cases of infection and the sex, the outcomes, and underlying
diseases. Conclusion: The results showed that PCP has a
relatively high prevalence among pediatric inpatients with respiratory
disorders. Neutropenia is a significant predisposing factor in these
patients. However, there is no correlation between PCP cases and the
outcomes and underlying diseases. Most of patients with PCP were
affected during the COVID-19 pandemic.
Calculated globulin is clinically useful as a screening test for antibody deficiency in Turkish adult patients
Authors: Akkor Aslı , Yeğit Osman Ozan , Karadağ Pelin , Karabacak Deniz Eyice , Oztop Nida , Beyaz Şengül , Tuzer Can , Can Ali , demir semra , Ünal Derya , İşsever Halim , Genç Sema , Ömer Beyhan , Jolles Stephen
Published: October 2022

Backgrounds: Heterogeneous clinical features of antibody
deficiency (AD) may cause diagnostic delays. Calculated globulin (CG)
(total protein minus albumin) has been proposed as a screening test to
prevent morbidity due to diagnostic delays in AD. Our aim is to validate
CG as a screening test in AD in Turkish adult patients by comparing its
role with gamma globulin analysis in protein electrophoresis.
Methods: Fifty serum samples were randomly collected for each
level of CG from 1.5 to 2.5 mg/dl and tested for serum IgG, IgA, IgM
levels and protein electrophoresis. Cut-off values predicting low IgG
levels were calculated for electrophoretically determined gamma globulin
and CG. Additionally, the data of 47 patients followed up in our clinic
with a diagnosis of primary antibody deficiency (PAD) were
retrospectively analyzed. Results: A total of 550 adult patients
were included in the study. The CG value predicting patients with IgG
<600 mg/dl as a screening test was determined as
<2.0 with 83.8% sensitivity and 74.9% specificity. The gamma
globulin value which predicted patients with the same IgG value of
89.0% sensitivity and 89.4% specificity was determined as
<0.7. In the retrospective analysis, 37 of 47 patients
(78.7%) with PAD had a CG value of <2.0 at the time of the
diagnosis and all 13 patients (%100) whose gamma globulin values were
measured at the time of the diagnosis had a gamma globulin value of
<0.7. Conclusion: The determined CG cut-off value of
<2.0 can be used as a screening test in Turkish adult
patients.
Calculation and analysis of the strong prism of the octagonal-quadrilateral networks
Authors: Liu Jia-bao , Wang Kang , Zheng Ya-Qian
Published: October 2022

Nowadays, with the development of the times, network structure analysis
has become a hot issue in some fields. The eigenvalues of normalized
Laplacian are very important for some network structure properties. Let
Qn be octagonal-quadrilateral networks composed of n octagons and n
squares and let Q2n be the strong prism of Qn. The strong product of a
complete graph of order 2 and a complete graph of order G forms a strong
prism of the graph G. In this paper, the decomposition theorem of the
associated matrix is used to completely investigate the normalized
Laplacian spectrum of Qn2. In addition, we establish exact formulas for
the degree-Kirchhoff index and the number of spanning trees of Qn2.
Deep Learning Based Beamforming for MISO Systems with Dirty-Paper Coding
Authors: Lou Xingliang , Xia Wenchao , Haitao Zhao , Wen Wanli , Li Xiaohui , Wang Bin
Published: October 2022

Beamforming technique can effectively improve the spectrum utilization
of multi-antenna systems, while the dirty-paper coding (DPC) technique
can reduce inter-user interference. In this letter, we aim to maximize
the weighted sum-rate under power constraint in a
multiple-input-single-output (MISO) system with the DPC. However, the
existing methods of beamforming optimization mainly rely on customized
iterative algorithms, which have high computational complexity. To
address this issue, by utilizing the deep learning technique and the
uplink-downlink duality, and carefully exploring the optimal solution
structure, we devise a beamforming neural network (BFNNet), which
includes a deep neural network module and a signal processing module.
Besides, we use the modulus of the channel coefficients as the input of
deep neural network, which reduces the input size. Simulation results
show that a well-trained BFNNet can achieve near-optimal solutions,
while significantly reducing computational complexity
Acute myeloid leukemia superimposed on hemophagocytic lymphohistiocytosis after COVID19 vaccination
Authors: Bhatt Shyam H. , Borowicz Violet , Stump Michael
Published: October 2022

Hemophagocytic lymphohistiocytosis (HLH) is a multi-system inflammatory
condition that has been observed as a rare adverse effect of the COVID19
vaccination. AML occurring in a pediatric patient as HLH enters
remission has never been documented previously. Our case describes a
17-year-old male who was treated for this pathology with
immunosuppressants and two different chemotherapeutic protocols. Due to
the aggressive nature of his MLL-rearranged genetic profile, this cancer
was pervasive and refractory to treatment.
Grassland stability: the role of biodiversity in the face of climate change
Authors: Hoss Daniela , Richter Aline , Vélez-Martin Eduardo , Menezes Luciana , Overbeck Gerhard , Debastiani Vanderlei , Pillar Valério
Published: October 2022

The effects of climate changes on the stability of plant communities is
a major concern, especially for the maintenance of ecosystem processes
and services. Biodiversity may buffer communities from the effects of
these disturbances, providing resistance and resilience. Here we assess
the interplay between biodiversity facets on resistance and resilience
of biomass productivity under anomalous dry and wet conditions in
subtropical grasslands. Overall, high levels of taxonomic and functional
biodiversity components, coupled to the community type derived from
functional traits, positively affected the resistance under anomalous
dry and wet conditions, whereas resilience was positively affected in
the recovery from wet periods. We conclude that increased diversity of
the plant communities can ensure ecosystem stability throughout the
climatic anomalies, but this is contingent on the biodiversity component
evaluated, the direction and intensity of the climatic anomaly, and the
functional structure of the communities.
Expanding the Concept of Materiality to Environmental, Social, and Governance: Audit Issues and Implications
Authors: Turner Lynn , Weirich Thomas R.
Published: October 2022

The concept of materiality has long been a basic feature in U.S. securities laws and regulations. With the current global and U.S. efforts to develop new disclosure standards for environmental, social, and governance, a debate has emerged regarding the expansion of the definition of materiality. An expanded definition would include not only financial materiality (i.e., how information affects an investor’s decision to buy or sell) but also environmental and social materiality (i.e., how a company’s operations impact the climate, its employees, consumers, and society). This is referred to as “double materiality” (European Union 2019). However, as discussed in this paper, the concept of materiality set forth in U.S. securities laws and court decisions are contrary to the concept of double materiality. This paper provides a brief history of materiality and expansion of the concept and discusses audit issues and implications.
Career Concerns, Contract Choice, and “Unpaid” Executives
Authors: Chen Hui , Luo Wei , Soderstrom Naomi
Published: October 2022

We examine a unique setting of publicly listed Chinese state-owned enterprises (SOEs), where some top executives are paid by government-controlled parent firms rather than by the firms where these executives work. Because their reported compensation is zero, these executives have been ignored in the literature. We find that the CEOs’ own personal characteristics, the nature of the CEO’s job responsibilities, and the environment in which the firm operates are significantly related to the CEO’s contract type. We also document that parent-paid CEOs have a significantly higher probability of future promotion than other CEOs. Compared to peer firms that directly pay their CEOs, firms with parent-paid CEOs have higher asset turnover. Contrary to concerns that parent-paid executives might extract resources from minority shareholders to the benefit of the parent SOE or local government, we document less use of tunneling or tax strategies under parent-paid contracts.

JEL Classifications: G30; J30; M12; M52.
Baseline Quality Improvement Capacity of 33 Endocrinology Centers Participating in the T1D Exchange Quality Improvement Collaborative
Authors: Marks Brynn E. , Mungmode Ann , Neyman Anna , Levin Laura , Rioles Nicole , Eng Donna , Lee Joyce M. , Basina Marina , Hawah-Jones Nana , Mann Elizabeth , O’Malley Grenye , Wilkes Meredith , Steenkamp Devin , Aleppo Grazia , Accacha Siham , Ebekozien Osagie
Published: October 2022

  

This article describes the evolution of the Type 1 Diabetes Exchange Quality Improvement Collaborative (T1DX-QI) provide insights into the development and growth of a successful type 1 diabetes quality improvement (QI) program. Since its inception 8 years ago, the collaborative has expanded to include centers across the United States with varying levels of QI experience, while simultaneously achieving many tangible improvements in type 1 diabetes care. These successes underscore the importance of learning health systems, data-sharing, benchmarking, and peer collaboration as drivers for continuous QI. Future efforts will include recruiting additional small- to medium-sized centers focused on adult care and underserved communities to further the goal of improving care and outcomes for all people living with type 1 diabetes. 
Enabling laser transmission welding of additively manufactured thermoplastic parts using an expert system based on neural networks
Authors: Kuklik Julian , Mente Torben , Wippo Verena , Jaeschke Peter , Kaierle Stefan , Overmeyer Ludger
Published: October 2022

In order to use laser transmission welding (LTW) for additively manufactured parts such as prototypes, small series, or one-off products, an enhanced process knowledge is needed to overcome the difficulties in the part composition resulting from the additive manufacturing process itself. In comparison to an injection molding process for thermoplastic parts, the additive manufacturing process fused deposition modeling leads to an inhomogeneous structure with trapped air inside the volume. In this paper, a neural network-based expert system is presented that provides the user with process knowledge in order to improve the weld seam quality of laser welded additively manufactured parts. Both additive manufacturing and LTW process are assisted by the expert system. First, the designed expert system supports the user in setting up the additive manufacturing process to increase the transmissivity. During welding, the additive manufacturing and LTW process parameters are used to predict the weld seam strength. To create the database for the expert system, specimens of transparent and black polylactide are additively manufactured. In order to change the transmissivity at an emission wavelength of 940 nm of the diode laser used, the manufacturing parameters for the transparent parts are varied. The transmissivity of the parts is measured with a spectroscope. The transparent samples are welded to the black samples with laser powers between 8 and 14 W in the overlap configuration and shear tensile tests are performed. In this work, the predictions of the transmissivity and the shear tensile force are demonstrated with an accuracy of more than 88.1% of the neural networks used for the expert system.