bluuebunny/crossref_metadata_2025 huggingface dataset:
Pedaling to Performance: Exploring the Effects of Pre-Tournament Cycling on Rocket League Esports Performance
Authors: Gaige Connor J. , Allen Leah E. , Krieger Joesi M. , Hagele Anthony M. , Sunderland Kyle L. , Kerksick Chad M. , Mumford Petey W.
Published: January 2024

Purpose

Exercise has been well documented to elicit cognitive benefits; therefore, we aimed to examine the effect on performance of a single bout of cycling exercise before an esports tournament.

Methods

Twenty healthy males (age, 24 ± 6 yr; height, 177.3 ± 7.3 cm; body mass, 80.7 ± 20.9 kg; ranked between Gold 1 and Champion 3) participated in a randomized, counterbalanced crossover study involving 1) a 20-min cycling exercise bout at 60%–70% heart rate reserve or 2) 20 min of rest before competing in an esports tournament. Tournaments consisted of 10 paired, rank-matched Rocket League 1 vs. 1 matches played in three series. Participants were assessed before and after the tournament for hemodynamics, cognition, and gameplay mechanics. Heart rate was monitored throughout the tournament, with gameplay performance and post-match surveys completed after each match.

Results

Exercising before the tournament led to higher initial fatigue (P= 0.002), higher average heart rates throughout the tournament (P< 0.001), lower perceived individual performance in series 1 (P= 0.03), lower overall perceived opponent performance (P= 0.03), and improved goal percentage in series 3 (P= 0.04) compared with rest. Participant save percentage decreased over time in both conditions (P= 0.04). No differences were observed in cognition measures, gameplay mechanics, or hemodynamics.

Conclusions

A single bout of cycling exercise completed before a Rocket League 1 vs. 1 tournament had no negative effects on performance or wins. It did, however, lower perceived match performance and fatigue at the beginning of the tournament while improving goal percentage during the last series.
Optical and electronic properties of transition metal dichalcogenides on pre-patterned surfaces
Authors: Κουρμουλάκης Γεώργιος
Published: January 2024

Τα δισδιάστατα διχαλκογεννή μέταλλα μετάβασης (2D-TMDs) παρουσιάζουν αξιοσημείωτες οπτοηλεκτρονικές ιδιότητες, καθιστώντας τα βασικά εργαλεία για την υλοποίηση προηγμένων συσκευών. Το άμεσο ενεργειακό χάσμα σε συνδυασμό με το σχηματισμό σταθερών εξιτονίων με ενέργειες δέσμευσης της τάξης των εκατοντάδων meVs, επιτρέπει την ισχυρή εκπομπή φωτοφωταύγειας (PL) ακόμη και σε θερμοκρασία δωματίου. Λόγω του ατομικού τους πάχους και της κρυσταλλικής συμμετρίας τους, αυτά τα υλικά υπόκεινται σε συγκεκριμένους κανόνες οπτικής επιλογής στους οποίους οι δείκτες κοιλάδας και σπιν συνδέονται εγγενώς δημιουργώντας ένα δυαδικό σύστημα που μπορεί να χρησιμοποιηθεί για αποθήκευση και επεξεργασία πληροφοριών. Παρά την ανθεκτικότητά τους στη μηχανική παραμόρφωση, τα 2D-TMD είναι εξαιρετικά ευαίσθητα στο διηλεκτρικό τους περιβάλλον. Σε αυτή τη διατριβή, διερευνούμε πώς τα οπτικά χαρακτηριστικά μιας ατομικής μεμβράνης WS2 (1L-WS2) επηρεάζονται από το υπόστρωμα. Αυτό το επιτυγχάνουμε μεταφέροντας τα δισδιάστατα υλικά σε ένα προσχεδιασμένο υπόστρωμα Si/SiO2 με κυλινδρικά πηγάδια με αποτέλεσμα τη δημιουργία τόσο αιωρούμενων όσο και τοπικά παραμορφωμένων περιοχών εντός της ίδιας μεμβράνης. Εξετάζουμε αυτή τη διαμόρφωση δείγματος με μέσα οπτικής φασματοσκοπίας και μη γραμμικής απεικόνισης. Η ευδιάκριτη εκπομπή PL που προέρχεται από το ουδέτερο εξιτόνιο (X0) σε αναρτημένες περιοχές υπογραμμίζει την επίδραση του υποστρώματος. Επιπλέον, δείχνουμε ότι οι μελέτη Δεύτερης Αρμονικής εξαρτώμενης από την πόλωση (P-SHG) μπορεί να είναι ένα εξ ολοκλήρου οπτικό εργαλείο για την παροχή μοτίβων εικόνας του κρυσταλλικού προσανατολισμού σχετιζόμενα με την παραμόρφωση του υλικού. Στο τελευταίο μέρος της διατριβής, μελετάμε την επίδραση της διαξονικής εφελκυστικής τάσης στην ενέργεια εξιτονίου και στην πόλωση σπιν-κοιλάδας της μεμβράνης WS2 πάνω από τον Γραφίτη. Τα πειραματικά μας αποτελέσματα μας επέτρεψαν να εξαγάγουμε την καθαρή επίδραση της διαξονικής εφελκυστικής τάσης στην μείωση της πόλωσης, την οποία αποδώσαμε στη μείωση του χρόνου ζωης του σπιν λόγω αύξησης της συχνότητας ιδιοπεριστροφής σε συνδυασμό με τη μείωση σκέδασης μέσω του καναλιού Κ-Λ στο ζώνη αγωγιμότητας. Τα αποτελέσματά μας καταδεικνύουν ότι η διαμόρφωση υποστρώματος και η μηχανική παραμόρφωση μπορούν να είναι σημαντικά εργαλεία για τον συντονισμό των ιδιοτήτων των 2D-TMD στην επιδίωξη της ανάπτυξης νέων οπτοηλεκτρονικών συσκευών.
The role of (un)realistic expectations about forensic science in understanding victim satisfaction with burglary investigations
Authors: Βαζακίδου Ελένη
Published: January 2024

Αυτή η διατριβή διερευνά τις αντιλήψεις των θυμάτων διαρρήξεων σχετικά με τα εγκληματολογικά-δικανικά στοιχεία και συγκεκριμένα εάν αυτά τα θύματα έχουν μη ρεαλιστικές προσδοκίες που μπορούν να επηρεάσουν την ικανοποίησή τους με την αστυνομική έρευνα της διάρρηξης. Το ευρύτερο κοινό μπορεί να έχει αλλοιωμένες αντιλήψεις γιατις εγκληματολογικές-δικανικές επιστήμες λόγω της μεγάλης δημοτικότητας των εγκληματολογικών ταινιών-σειρών φαντασίας, σύμφωνα με τη βιβλιογραφία για το φαινόμενο του CSI (CSI Effect). Αν και η συγκεκριμένη βιβλιογραφία έχει παραμελήσει τα θύματα του εγκλήματος, έχει εξετάσει τις αντιλήψεις του ευρύτερου κοινού (κυρίως των ενόρκων) για τα εγκληματολογικά-δικανικά στοιχεία που συλλέγονται στον τόπο του εγκλήματος προκειμένου να προσδιοριστεί εάν υπάρχει το φαινόμενο του CSI, προτείνοντας ότι οι ένορκοι έχουν μη ρεαλιστικές προσδοκίες για τα εγκληματολογικά-δικανικά στοιχεία. Η παρούσα διατριβή υιοθετεί μια νέα προσέγγιση, χρησιμοποιώντας μια διαδεδομένη ψυχολογική θεωρία στην εξήγηση της ικανοποιήσης του καταναλωτή, δηλαδή τη θεωρία της διάψευσης των προσδοκιών (expectancy disconfirmation theory) για να εξηγήσει τον αντίκτυπο τέτοιων μη ρεαλιστικών προσδοκιών στην ικανοποίηση των θυμάτων των διαρρήξεων με την αστυνομική έρευνα. Τα θύματα είναι καταναλωτές των εγκληματολογικών υπηρεσιών της αστυνομίας και γι αυτό το λόγο η συγκεκρίμενη θεωρία, έχει χρησιμοποιηθεί από λίγες έρευνες για να εξηγηθούν οι παραγόντες που επηρεάζουν την ικανοποίηση των θυμάτων με την αστυνομία. Όμως αυτές οι έρευνες δεν εξέτασαν τον πιθανό ρόλο των μη ρεαλιστικών προσδοκιών για τα εγκληματολογικά- δικανικά στοιχεία. Με βάση τη θεωρία της διάψευσης των προσδοκιών, η διατριβή υποθέτει ότι τα θύματα που έχουν μη ρεαλιστικές προσδοκίες για τα εγκληματολογικά-δικανικά στοιχεία είναι πιθανό να αισθάνονται δυσαρεστημένα, καθώς η αστυνομία και η σήμανση δεν θα μπορέσουν να ανταποκριθούν σε τέτοιες προσδοκίες. Για την εξέταση αυτού του θέματος, η παρούσα διατριβή χρησιμοποίησε μια προσέγγιση μεικτής μεθόδου. Ποσοτικά δεδομένα συγκεντρώθηκαν από ένα ερωτηματολόγιο απευθυνόμενο σε θυμάτα διαρρήξεων (N=100) προκειμένου να εξεταστεί η επίδρασητων μη ρεαλιστικών προσδοκιών των θυμάτων για τα εγκληματολογικά-δικανικά στοιχεία στην ικανοποίηση τους. Προς συμπλήρωση αυτών των ευρημάτων, ποιοτικά δεδομένα συλλέχθηκαν από μια μελέτη δύο μερών που αφορούσεσυνεντεύξεις (N=6) και μια διαδικτυακή έρευνα (N=24) με ερευνητές της σήμανσης (CSIs). Τα αποτελέσματα δείχνουν ότι τα θύματα διαρρήξεων μπορεί να έχουν μη ρεαλιστικές προσδοκίες για τα εγκληματολογικά-δικανικά στοιχεία, πράγμα που είναι σε συμφωνία με τη βιβλιογραφία για το φαινόμενο του CSI, οι οποίες έχουν αρνητικό αντίκτυπο στηνικανοποίηση σε σχέση με την έρευνα της σήμανσης στον τόπο του εγκλήματος. Η παρούσα διατριβή συμβάλει με μοναδικό τρόπο στην ακαδημαϊκή έρευνα για την ικανοποίηση των θυμάτων και στην ακαδημαϊκή έρευνα για το φαινόμενο του CSI, εξετάζοντας ένα πρωτότυπο θέμα και χρησιμοποιώντας έναν καινοτόμο ερευνητικό σχεδιασμό.
Ο βυζαντινός οικισμός της Μεσσήνης (300-800 μ.Χ.)
Authors: Τσιβίκης Νικόλαος
Published: January 2024

Στην παρούσα μελέτη καταγράφεται συστηματικά η συνολική αρχαιολογική εικόνα μιας επαρχιακής πρωτοβυζαντινής πόλης στο νοτιοδυτικό άκρο της Ελληνικής χερσονήσου, όπως αυτή διαμορφώνεται και αλλάζει στους πέντε αιώνες ιστορίας από το 300 περ. μ.Χ. και μέχρι και το 800 μ.Χ. Τί είναι αυτό που αλλάζει σε μια πόλη από το τέλος του αρχαίου κόσμου και στην πορεία προς τη γέννηση ενός νέου μεσαιωνικού; Ποιες είναι οι αρχαιολογικές ενδείξεις αυτής της διαδικασίας και πως μπορούμε να τις καταγράψουμε, να τις οργανώσουμε και να τις μελετήσουμε; Επιπλέον κατά πόσο και με ποιο τρόπο οι αλλαγές που παρατηρούμε στην αρχαιολογική καταγραφή εκφράζουν αλλαγές στις κοινωνίες που παράγουν τον υλικό πολιτισμό που εμείς ανασκάπτουμε; Και ταυτόχρονα με ποιο τρόπο συνομιλούν οι παρατηρούμενες αυτές αλλαγές με τις ιστοριογραφικές μας κατασκευές για την κατανόηση του παρελθόντος; Συγκεκριμένα, πρώτος στόχος υπήρξε η συνθετική παρουσίαση ενός οικισμού που ζει και αλλάζει σύμφωνα με τις ανάγκες των κατοίκων του, πάντοτε βέβαια κάτω από την επίδραση των γεγονότων της μεγάλης κλίμακας. Ένας δεύτερος αλλά εξίσου σημαντικός στόχος υπήρξε η αποτύπωση της λειτουργίας ενός πρωτοβυζαντινού οικισμού, η καταγραφή των κτηρίων και των μνημείων του, μέσα από την ανάδειξη και διάσωση των σχετικών αρχαιολογικών πληροφοριών. Συνολικότερα η μελέτη αποτέλεσε μια δοκιμή, όπου η πρωτοβυζαντινή Μεσσήνη καθίσταται ένα παράδειγμα για τη μελέτη των επαρχιακών πρωτοβυζαντινών οικισμών.
Method development for identification of tachykinins and their post-translational modifications and discovery with in silico analysis of bio-informatic databases
Authors: Δεληκωνσταντίνου Γεωργία
Published: January 2024

Οι ταχυκινίνες είναι πεπτίδια σηματοδότησης που απελευθερώνονται από την επεξεργασία προδρόμων ουσιών προπρωταχυκινίνης, τα οποία υπόκεινται σε μετα-μεταφραστικές τροποποιήσεις, συμπεριλαμβανομένης της αμίδωσης. Οι ταχυκινίνες δρουν στους τρεις υποδοχείς ταχυκινίνης NK1, NK2 και NK3. Η διαφορική επεξεργασία των προδρόμων ουσιών της προπρωταχυκινίνης μπορεί να οδηγήσει στο σχηματισμό ποικίλου φάσματος ταχυκινινών (συμπεριλαμβανομένων των εκτεταμένων μορφών). Τα προηγούμενα ευρήματά μας, έδειξαν αυξημένη πρωτεολυτική διάσπαση των προδρόμων των ανθρώπινων TAC3 και TAC4 προπρωταχυκινίνης από τον πλακούντα σε παθολογικές καταστάσεις όπως η προεκλαμψία συγκρίσιμη με αυτή που βρίσκεται στον εγκέφαλο. Αυτή η μελέτη έχει αναπτύξει μια πειραματική στρατηγική για τη σύλληψη και την ανίχνευση ταχυκινινών που συνδυάζει εκχύλιση πεπτιδίων, εμπλουτισμό με καθαρισμό ανοσοσυγγένειας, διαχωρισμό RP-HPLC και MALDI-TOF. Η συνδυασμένη εφαρμογή αυτών των μεθόδων σε εγκέφαλο αρουραίου αναγνώρισε το mHK-1 ως αμιδωμένο δεκαπεπτίδιο και επίσης συνέλαβε και ανίχνευσε το Substance P. Η ανίχνευση μιας τροποποιημένης μορφής mHK-1 στον εγκέφαλο που ταιριάζει με τη μάζα μιας επιπρόσθετης ακετυλομάδας (+42 π.μ. u.) υποδεικνύει την ύπαρξη ειδικής για το νευροπεπτίδιο μετα-μεταφραστική τροποποίηση. Ο ρόλος της ακετυλίωσης είναι να παρέχει μεγαλύτερη σταθερότητα για το πεπτίδιο και συγγένεια δέσμευσης για τον υποδοχέα του. Η μεθοδολογία που περιγράφεται σε αυτή την έρευνα θα μπορούσε να εφαρμοστεί για τη δέσμευση ταχυκινινών που εκφράζονται σε φυσιολογικούς, προεκλαμπτικούς και πλακούντες IUGR, προκειμένου να διερευνηθούν οι αλλαγές που συμβαίνουν στην επεξεργασία των πρόδρομων ουσιών κατά τη διάρκεια παθήσεων όπως η προεκλαμψία και να εντοπιστούν μεταφραστικές τροποποιήσεις. Διεξήχθη μια παράλληλη in silico ανάλυση των δημοσίως προσβάσιμων βάσεων δεδομένων NCBI και Ensembl για τον εντοπισμό πρόδρομων ουσιών ταχυκινίνης. Επίσης διερευνήθηκε η φυλογενετική σχέση μεταξύ των ταυτοποιημένων ειδών. Συλλογικά, τα αποτελέσματα επεκτείνουν τον αριθμό των γνωστών ή προβλεπόμενων ταχυκινινών και πεπτιδίων που σχετίζονται με το γονίδιο της ταχυκινίνης. Επιπλέον, διαχωρίζουν τις πρόδρομες ενώσεις της προπρωταχυκινίνης σε τρεις διακριτές ομάδες. Η ανάλυση ρίχνει επίσης φως στην εξέλιξη των θέσεων διάσπασης του προδρόμου της ταχυκινίνης (π.χ. η Ν-τερματική μονοβασική θέση διάσπασης του ανθρώπινου ΕΚΑ/Β). Συνολικά, αυτή η μελέτη έχει αναπτύξει τεχνολογίες για τον εντοπισμό τροποποιήσεων προδρόμου ταχυκινίνης μετά τη μετάφραση που μπορεί να χρησιμεύσει ως εργαλείο για τον προσδιορισμό διαφορετικών πεπτιδικών φυσιολογιών μεταξύ νευρωνικών και περιφερικών ιστών και διαφορετικών καταστάσεων ασθένειας.
The COVID-19 pandemic and the incidence of acute coronary syndromes at General Hospital of Veroia
Authors: Sdogkos Evangelos , Roditis Pavlos , Papadopoulos Antonios , Spahiu Anila , Aidinis Andreas , Pliatsika Maria , Vogiatzis Ioannis
Published: January 2024

Background: Although deaths from Acute Coronary Syndromes (ACS) are the most prevalent globally, during the outbreak of the new SARS-CoV-2 coronavirus pandemic, there was a declining trend in hospital admissions for ACS patients. Inevitably a reduction of invasive procedures in cardiac catheterization laboratories was observed. Moreover, an increase in sudden out-of-hospital cardiac deaths was recorded. On the other hand, patients that eventually treated in the hospital had a much worse outcome in terms of cardiac function. Inadequate treatment of acute myocardial infarction resulted in a further increase in mortality due to coronary artery disease.
The aim of our study was the comparison of admissions of the patients with ACS before and during the COVID-19 pandemic.
Methods: A retrospective single center study was conducted. We recorded all admissions with ACS underwent  invasive interventions during the period of lockdown due to COVID-19 pandemic, in Greece, from 16 March 2020 to 1 May 2020 (study period A), as well as in the period of gradual withdraw of restrictions from 2 May 2020 to 1 June 2020 (study period B),. The data were compared with those of the periods of 2019 (control period A and B).
Results: One hundred thirty eight patients were the group of study period and 158 were the group of the control period. The reduction rate was 12.7% in study period. The largest decrease in admissions concerned with elderly patients over 75 years old, as well as females (by 52% - 53% respectively). The severity of the restrictions but also the fear of the spread of the coronavirus may be relevant to the insufficient seek of help for these groups of patients.
Conclusion: Our study showed that during the pandemic period, the invasive interventions were fewer than those of 2019. However, the expected reduction of catheterizations during this two and a half months period was mitigated by the increase of inter-hospital transfers of patients with ACS from neighboring hospitals, without a catheterization laboratory.
The role of job crafting as an employee strategy in responding to organizational change and job satisfaction in health units in Greece: Cross sectional study
Authors: Digonis Stefanos , Giannouli Anastasia
Published: January 2024

Background: In recent decades, in the context of organizational change, Job crafting is the process in which the redesign of work takes place, employees change their labor boundaries and labor relations to find meaning in them.
Material and Method: Data were collected from 112 health care workers from the public and private sector regardless of specialty with a random sampling method. The data was collected by a questionnaire that included three parts: demographics, scale of organizational commitment, job satisfaction. The data was analyzed with SPSS version 24.0 using descriptive statistics, Pearson correlation, variance analysis and t-test.
Purpose: To investigate job crafting as a strategy of employees in Health Units in Greece regarding organizational change and the factors that affect job satisfaction.
Results: A statistically significant positive correlation was identified between the RCT scale and the MSQ satisfaction scale (r=0.299, p=0.002a=0.05), while it is rejected for the MSQ scale (F=3.757, p-value=0.027a=0.05) with application of One Way ANOVA. There was also no statistically significant difference (χ2(3)=2.068, p-value=0.558>a=0.05) so there is no differentiation in the degree of agreement of the MSQ scale per educational level. Finally, the hypothesis of equality of population fluctuations is not rejected (Vene test, F=2,507, p=0,116) and a statistically significant relationship between the Job Crafting scale in relation to the employment agency (t=-2,607, p=0,01) emerged.
Conclusions: Job crafting has a positive impact on organizational change and job satisfaction is positively linked to the implementation of Job crafting. Planning and managing organizational change is a complex and difficult task for organizational managers. Reactions to organizational change can be multiple, often ambiguous and complex. Employees can respond to change in unexpected ways. They don't just face change, but they may also be actively involved with it and play an active role in influencing its direction. On the one hand, organizations and, on the other hand, managers should turn to work redesign interventions, leave room for employees to change their work routine and provide them with opportunities to "match" their work to their strengths, skills and preferences.
Hospital liaison nurse develops an effective post cardiac device implant discharge planning
Authors: Kadda Olga
Published: January 2024

No abstract available
Extending the Reporting Items of Practice Guidelines in Healthcare (RIGHT) statement for reporting Chinese patent medicine guidelines: a protocol
Authors: Li Xuanlin , Huang Lin , Zhou Qi , Xie Zhijun , Hu Xuanming , Chen Yaolong , Wen Chengping
Published: January 2024

Background: Based on the main document of the Reporting Items of Practice Guidelines in Healthcare (RIGHT) statement, this study will aim to develop the reporting checklist applicable to the guidelines of Chinese patent medicine (CPM).

Methods: According to the methodology recommended by the Enhancing the QUAlity and Transparency Of health Research (EQUATOR) network, three well-defined working groups were established, namely the coordination team, the advisory group, and the Delphi panel. The coordination team conducted a literature analysis of the already published CPM guidelines, the extensions of the RIGHT statement, and CPM related reporting specifications to initially form an initial item pool. The Delphi panel of multidisciplinary backgrounds will conduct two rounds of Delphi questionnaires to identify an extension item for RIGHT for CPM. These questionnaires will be sent to each Delphi panel member via email, and each member will independently fill out and provide comments within 10 working days of receiving the questionnaire. Finally, feedback will be provided to the coordination team and the post efficacy assessment of the already published clinical practice guidelines for CPM to determine the final items for RIGHT for CPM checklist.

Dissemination: The extended version of the RIGHT for CPM checklist will be published in a peer reviewed journal.

Conclusion: We hope that the upcoming RIGHT for CPM checklist provides detailed guidance for developers and users of CPM guidelines, further improving the quality of reports, and promoting the effective dissemination and implementation of CPM guidelines.
On the Question of the Relevance of the Philosophical-Anthropological Paradigm in Education
Authors: Viktoruk Elena , Chernyaeva A. , Myshkovskaya A.
Published: January 2024

Social, cultural and technological changes necessitate the search for new paradigms in education. One solution may be associated with an anthropological approach that integrates philosophical, psychological and educational anthropology. The anthropological approach most fully reveals the essence of education as a phenomenon associated with human. The authors consider the problem of identifying educational technologies that will provide solutions to educational problems in a changing reality. It was found in the research that the pedagogical ideas that have developed in anthropological teachings reveal the desired image of a person and the methods of its formation. Thus, the anthropological approach in education demonstrates its effectiveness, since it allows us to consider a person as a sociocultural subject, whose behavior and development are determined by interaction with other people and the social environment. The analysis of anthropological views made it possible to identify two positions: the first is based on the ideas of uniqueness and self-creation of the individual, the subject-subject model of interaction, dialogue forms of communication, the second shifts the emphasis to the environment in which the formation and cultivation of the individual by society occurs. Analysis of approaches and concepts allows us to state the dynamics of the anthropological approach itself and the coexistence of various programs within the framework of approaches united conceptually.
Development of Creative Potential of Youth in Extracurricular Activities on the Model of School Game (Creative) Club
Authors: Sizov A.
Published: January 2024

The article presents the results of the pilot empirical study on the development of creative potential of young people by means of game and art technologies. It is shown that the existing methodological developments are aimed at the development of highly specialized skills, but not at the creative potential in the broad sense. In order to remove this limitation, the technology of game (creative) club in school extracurricular activities is proposed.

Creative potential, according to the concept of J. Renzulli, is considered as a complex of intellectual, motivational and creative factors. It is hypothesized that active intellectual-developmental game (creative) activities help to identify and form the creative potential of adolescents. Game (creative) technologies (TRIZ, acting exercises, the game "Mafia") were used as means of development. In order to test the hypothesis, we used the method of expert evaluation according to the method of S.M. Platonova for the evaluation of general aptitude and statistical analysis of the obtained empirical data.

The results reflect a qualitative change of creative potential of the experimental group at all levels of creative potential: intellectual, motivational and creative. The model of the school game club is proposed as a technology for the development of creative potential not only of adolescents, but also of teachers in the practice of extracurricular school activities.
Trends and Prospects for the Development of Higher Education in China
Authors: U Uzyahen
Published: January 2024

The article is devoted to the analysis of general trends and characteristics of the current state of the Chinese education system. The author analyzes the dynamics of important indicators of education development, such as the number of universities, the number of university students, the ratio of students to the total population, as well as some qualitative indicators. Much attention was paid to the importance and prospects of state support for all levels of the Chinese education system. As recommendations, the necessity of creating state (federal) and regional systems for forecasting and monitoring the current and future needs of the labor market in personnel of various specialties and qualifications, including taking into account global trends, is justified; the creation of a modern, mobile and flexible system of continuing professional education (as an integral part of the general system of continuing education), including vocational education at all levels.
Estudio criminológico sobre la inseguridad en las áreas rurales a partir del uso de herramientas TIC.
Authors: Ortiz García Jordi , Rodrigues Antúnez Ricardo
Published: January 2024

La percepción de inseguridad y el miedo al delito han sido sobradamente analizados en la literatura criminológica nacional e internacional. Desafortunadamente, los estudios realizados se han centrado principalmente en las ciudades y sus barrios. Esta investigación tiene como finalidad conocer la inseguridad y el miedo que existe en las áreas rurales de nuestro país. Para ello, hemos llevado a cabo un estudio de victimización en la localidad de Cilleros, un municipio al noroeste de la provincia de Cáceres en la Comunidad Autónoma de Extremadura de 1.617 habitantes. Para este estudio se ha empleado una metodología geoestadística, y cuyos resultados muestran mayoritariamente que las personas se sienten seguras, pero arrojan también un número relevante de ilícitos acaecidos conforme al tamaño de la población o la necesidad de una mayor presencia policial en este municipio.
Blockchain e implicaciones procesales en materia probatoria.
Authors: Martín Meneses Andrea
Published: January 2024

La aplicación de las nuevas tecnologías en la Administración de Justicia abre una puerta a la modernización, agilización y simplificación de los trámites procesales. Pese a que muchos consideran que pueden traer consigo una auténtica revolución de esta institución, es fundamental estudiar si realmente estas nuevas tecnologías son compatibles con los principios y garantías inherentes al sistema procesal español y, en caso afirmativo, habría que determinar cuáles son sus límites y en qué procedimientos podría utilizarse. Una de las más prometedoras actualmente es la tecnología blockchain, un sistema descentralizado basado en el consenso entre los usuarios y caracterizado por la inmutabilidad, la transparencia y la irrevocabilidad. En este trabajo, analizaremos el impacto que la implementación de la tecnología de la cadena de bloques puede ocasionar en el proceso civil, concretamente en materia probatoria, deslindando su caracterización como fuente y medio de prueba en el proceso con base en la normativa hoy vigente.
Derecho y ciencia: entre la dignidad humana y la inteligencia artificial.
Authors: Breceda Pérez Jorge Antonio , Castillo Lara Clara
Published: January 2024

La inteligencia artificial (IA) impacta todos los ámbitos y resalta su enorme potencial para transformar la vida diaria en este siglo XXI. No obstante, a medida que se integra cada vez más en nuestras vidas, resulta crucial reflexionar sobre su influencia en la dignidad humana. Este ensayo aborda precisamente la IA y la dignidad humana, examinando los desafíos y riesgos que plantea, así como las múltiples posibilidades y oportunidades en la vida. Aparte de explorar la ética y su regulación en la gobernanza de la IA, los cambios sociales y económicos que puede forjar. El objetivo principal aquí es el debate crítico sobre el uso de la ciencia, en el derecho para garantizar la dignidad humana.
Giving patients more choice: exploring the use of energy-based devices in medical aesthetics
Authors: Mclean Michelle
Published: January 2024

Michelle McLean, an Advanced Nurse Practitioner, delves into the increasing use of energy-based devices and provides insight into the efficacy of radiofrequency (RF) in the field of medical aesthetics
Molecular Analysis of Alternative Spliced Transcripts of Equine Pleckstrin Homology and RhoGEF Domain Containing G1 (PLEKHG1) gene
Authors: Park Jeong-Woong , Choi Jae-Young , Kim Kyoung Hwan , Kim Sujung , So Jae-rung , Kim Byeong-Woo , Cho Byung-Wook
Published: January 2024

Since horse industry get bigger with horse racing and horse riding, athletic performance become most important trait on horses, but the molecular analysis and regulatory pathway studies remain insufficient for evaluation and prediction of horse athletic abilities. In our previous study, we conducted RNA-sequencing analysis with muscle and blood samples by exercise in Thoroughbreds. Through RNA-sequencing, we identified Pleckstrin Homology and RhoGEF Domain Containing G1 (PLEKHG1) gene expressed differentially by alternative spliced isoforms in skeletal muscle during exercise. In this study, we conducted reverse transcriptase polymerase chain reaction (RT-PCR) to validate two isoforms of equine PLEKHG1 transcripts (PLEKHG1a, PLEKHG1b), and cloned the transcripts to confirm the sequences. Additionally, we validated expression pattern of PLEKHG1a (long form of transcript) and PLEKHG1b (short form of transcript) in horse tissue by quantitative RT-PCR (qRT-PCR). Prediction of protein structure of these isoforms revealed two putative phosphorylation sites at the amino acid sequences encoded in exon 7, which is deleted in PLEKHG1b. Expression pattern of PLEKHG1a and PLEKHG1b shows cross expressed pattern as RNA-sequencing data. PLEKHG1a increased after exercise whereas PLEKHG1b decreased after exercise. Collectively, it is assumed that the expression patterns of PLEKHG1a and PLEKHG1b transcripts would be involved in regulation of myogenic differentiation and myogenic proliferation through the Ras signaling pathway. Further study should be necessary to uncover biological function(s) and significance of the alternative splicing isoforms in equine skeletal muscle
Implementation and demonstration of digital twin system for plant factory
Authors: Ko Tae-Hwan , Han Seok-Ho , Lee Hea-Min , Noh Dong-Hee , Heo WonDeok , Chin ByungGak , Park Jong Seok
Published: January 2024

This study described the results of implementing the framework of the digital twin system for the digitization of plant factories. The purpose of this invention is to implement a system based on digital twins that can control and monitor the optimal environment for foliage containing functional components grown in plant factories. In this paper, for the realization of such a system, a digital twin framework that can be applied universally to plant factories was designed. This design structure was largely designed by dividing it into 1) the physical world layer, 2) the cyber and physical interaction layer, 3) the digital twin system layer, and 4) the application layer. In this study, the plant factory digital twin framework designed in this way was demonstrated in the test bed space of a company operating a plant factory in Chungcheongnam-do.
Analysis of 38 kW class agricultural tractor engine load rate according to agricultural operation
Authors: Yang Cheol Woo , Jeon Hyeon Ho , Baek Seung Yun , Baek Seung Min , Kim Yong Joo
Published: January 2024

This study was conducted to analyze the engine load ratio of a 38 kW agricultural tractor to calculate national emissions. Engine output was calculated using engine CAN (Controller area network) data measured through a load measurement system. In this study, plow tillage (PT) and rotary tillage (RT), which are the main agricultural tasks of small and medium horsepower tractors, were selected and performed three times for each stage. The engine load ratio was calculated as the ratio of the engine power generated during work and the engine rated power, and weights (25% each for PT M1, PT M2, RT L3, and RT L4) according to the agricultural work ratio were applied. The engine load ratio was found to be an average of 0.68 and 0.75 for the M1 and M2 stages of plow tillage work, respectively, and an average of 0.57 and 0.65 for the L3 and L4 stages of rotary tillage work, respectively. The weighted load ratio was 0.17, 0.19, 0.14, and 0.16 for plow tillage operation M1, M2, and rotary tillage operation L3 and L4, respectively. The integrated load factor was found to be 0.66, which is approximately 1.38 higher than the current domestic load factor of 0.48.
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection
Authors: Lin Junqing , Suo Jinlong , Bao Bingbo , Wei Haifeng , Gao Tao , Zhu Hongyi , Zheng Xianyou
Published: January 2024

Aims

To investigate the efficacy of ethylenediaminetetraacetic acid-normal saline (EDTA-NS) in dispersing biofilms and reducing bacterial infections.

Methods

EDTA-NS solutions were irrigated at different durations (1, 5, 10, and 30 minutes) and concentrations (1, 2, 5, 10, and 50 mM) to disrupt Staphylococcus aureus biofilms on Matrigel-coated glass and two materials widely used in orthopaedic implants (Ti-6Al-4V and highly cross-linked polyethylene (HXLPE)). To assess the efficacy of biofilm dispersion, crystal violet staining biofilm assay and colony counting after sonification and culturing were performed. The results were further confirmed and visualized by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). We then investigated the efficacies of EDTA-NS irrigation in vivo in rat and pig models of biofilm-associated infection.

Results

When 10 mM or higher EDTA-NS concentrations were used for ten minutes, over 99% of S. aureus biofilm formed on all three types of materials was eradicated in terms of absorbance measured at 595 nm and colony-forming units (CFUs) after culturing. Consistently, SEM and CSLM scanning demonstrated that less adherence of S. aureus could be observed on all three types of materials after 10 mM EDTA-NS irrigation for ten minutes. In the rat model, compared with NS irrigation combined with rifampin (Ti-6Al-4V wire-implanted rats: 60% bacteria survived; HXLPE particle-implanted rats: 63.3% bacteria survived), EDTA-NS irrigation combined with rifampin produced the highest removal rate (Ti-6Al-4V wire-implanted rats: 3.33% bacteria survived; HXLPE particle-implanted rats: 6.67% bacteria survived). In the pig model, compared with NS irrigation combined with rifampin (Ti-6Al-4V plates: 75% bacteria survived; HXLPE bearings: 87.5% bacteria survived), we observed a similar level of biofilm disruption on Ti-6Al-4V plates (25% bacteria survived) and HXLPE bearings (37.5% bacteria survived) after EDTA-NS irrigation combined with rifampin. The in vivo study revealed that the biomass of S. aureus biofilm was significantly reduced when treated with rifampin following irrigation and debridement, as indicated by both the biofilm bacterial burden and crystal violet staining. EDTA-NS irrigation (10 mM/10 min) combined with rifampin effectively removes S. aureus biofilm-associated infections both in vitro and in vivo.

Conclusion

EDTA-NS irrigation with or without antibiotics is effective in eradicating S. aureus biofilm-associated infection both ex and in vivo.

Cite this article: Bone Joint Res 2024;13(1):40–51.
PRÁTICAS EDUCATIVAS DE LEITURA NA EDUCAÇÃO INFANTIL E AÇÕES DOS BEBÊS E CRIANÇAS: RELATOS DE OBSERVAÇÃO
Authors: Martins Bizarria Geisa Aparecida , Pereira Lima Rita de Cassia
Published: January 2024

A investigação presente neste relato refere-se a uma escola de Educação Infantil de uma cidade do Vale do Paraíba paulista, vinculada a uma Rede de Ensino Municipal pública cuja Educação Infantil realiza um programa específico de aulas de Literatura. Participaram do estudo nove professoras. Este texto apresenta práticas educativas de leitura realizadas junto aos bebês e crianças bem pequenas por essas professoras. O relato é um recorte de uma tese de doutorado de abordagem qualitativa que investigou, à luz dos estudos de Moscocivi, as representações sociais de leitura na primeira infância por professoras de creche. Tal tese consistiu-se num estudo de caso, cujos dados foram gerados por entrevistas, análise documental e observação de propostas de leitura. Contudo, os dados aqui apresentados tiveram origem pela observação participante revelando aspectos de destaque, para as pesquisadoras, nas práticas educativas dessas professoras e nas respostas dos bebês e crianças a elas.
O ENEM NO GOVERNO FEDERAL BRASILEIRO: FUNÇÕES DO EXAME NO CENÁRIO DA POLÍTICA E GESTÃO EDUCACIONAL
Authors: De Sousa Sobrinho Aysllan , Rodrigues Cavalcanti Cacilda
Published: January 2024

O artigo discute a utilidade dada aos exames de larga escala na política e gestão da educação nacional. Objetivou-se analisar as funções do Exame Nacional do Ensino Médio na política e gestão educacional brasileira em diferentes períodos do governo federal. Para tanto, realiza-se uma pesquisa documental com base nos editais, portarias e decretos que abordam a funcionalidade do exame no período de 1998 a 2022, fundamentada na epistemologia sociocrítica dos estudos sobre a avaliação educacional. Conclui-se que o Enem tem exercido diferentes papéis no cenário educacional, sobretudo, como mecanismo de seleção para o ensino superior, no contexto da meritocracia de políticas neoliberais, em que, na falta de oportunidades para todos, o exame seleciona os mais aptos para a continuidade dos estudos, validando a competitividade, a meritocracia e a responsabilização na gestão da política educacional.
The increasing trend in the consumption of ultra-processed food products is associated with a diet related to chronic diseases in Colombia—Evidence from national nutrition surveys 2005 and 2015
Authors: Cediel Gustavo , Cadena Elisa María , Vallejo Pamela , Gaitán Diego , Silva Gomes Fabio Da
Published: January 2024

Introduction

Ultra-processed food products (UPF) have been related to chronic diseases (CD). Public health politics has been establishing strategies to decrease the consumption of these products in the country.

Objectives

i) To assess the trend of the consumption of UPF between 2005 and 2015. (ii) its association with sociodemographic factors and the overall dietary content of nutrients related to CD in 2015. (iii) to estimate the Population Attributable Fraction of unhealthy nutrient intake in Colombia in 2015 due to ultra-processed food consumption.

Methods

We used data from the first (2005) and the last (2015) National Surveys of the Nutritional Status in Colombia. Food consumption was assessed using a 24-hour food recall. The NOVA classification classified the food items according to the extent and purpose of industrial processing.

Results

The consumption of processed and UPF increased in Colombia between 2005 and 2015. In 2015, no significant differences were found in the consumption of UPF between men and women but significant differences by age, wealth index, area of residence, and ethnicity (p<0.001). A significant positive association was found between the dietary share of UPF and the content of CD-related nutrients such as free sugars, total fats, saturated fats, trans-fats, and sodium. The prevalence of excessive intake of all CD-related nutrients (according to WHO recommendations) increased across quintiles of the dietary share of UPF. With the reduction of UPF consumption to the level seen among the 20% lowest consumers [1.0% (0–4.5%) of the total energy from UPF], the prevalence of excessive nutrient intake was almost three-fourths lower for trans fats; around one third lower for free sugar and saturated fats, 26% lower for sodium and 15% lower for total fat.

Conclusions

In Colombia, the increasing trend in the consumption of UPF is associated with increasing intake of CD-related nutrients. Thus, reducing the consumption of UPF is a potentially effective way to achieve the nutritional goals of the WHO for the prevention of CD.
Unraveling the plasticity of translation initiation in prokaryotes: Beyond the invariant Shine-Dalgarno sequence
Authors: Estrada Karel , Garciarrubio Alejandro , Merino Enrique
Published: January 2024

Translation initiation in prokaryotes is mainly defined, although not exclusively, by the interaction between the anti-Shine-Dalgarno sequence (antiSD), located at the 3’-terminus of the 16S ribosomal RNA, and a complementary sequence, the ribosome binding site, or Shine-Dalgarno (SD), located upstream of the start codon in prokaryotic mRNAs. The antiSD has a conserved 5’-CCUCC-3’ core, but inter-species variations have been found regarding the participation of flanking bases in binding. These variations have been described for certain bacteria and, to a lesser extent, for some archaea. To further analyze these variations, we conducted binding-energy prediction analyses on over 6,400 genomic sequences from both domains. We identified 15 groups of antiSD variants that could be associated with the organisms’ phylogenetic origin. Additionally, our findings revealed that certain organisms exhibit variations in the core itself. Importantly, an unaltered core is not necessarily required for the interaction between the 3’-terminus of the rRNA and the region preceding the AUG of the mRNA. In our study, we classified organisms into four distinct categories: i) those possessing a conserved core and demonstrating binding; ii) those with a conserved core but lacking evidence of binding; iii) those exhibiting binding in the absence of a conserved core; and iv) those lacking both a conserved core and evidence of binding. Our results demonstrate the flexibility of organisms in evolving different sequences involved in translation initiation beyond the traditional Shine-Dalgarno sequence. These findings are discussed in terms of the evolution of translation initiation in prokaryotic organisms.
Antimicrobial resistance patterns of WHO priority pathogens isolated in hospitalized patients in Japan: A tertiary center observational study
Authors: Nisa Tania Tabassum , Nakatani Daisaku , Kaneko Fumie , Takeda Toshihiro , Nakata Ken
Published: January 2024

Background

After issuing the “Global action plan on antimicrobial resistance” in 2015, the World Health Organization (WHO) established a priority pathogens list for supporting research and development of novel antimicrobials. We conducted a comprehensive analysis of the WHO priority organisms in a Japanese tertiary hospital to apprehend the local AMR epidemiology.

Methods

Data were obtained from electrical medical records in Osaka University Hospital between January 2010 and March 2021. The critical, high, and medium “priority pathogens list” categories of the WHO were used to compare results between the early (2010–2015) and late (2016–2021) phases.

Results

Out of 52,130 culture-positive specimens, a total of 9,872 (18.9%) contained WHO priority isolates. In comparison to early phases, late phases were likely to have higher rates of carbapenem resistance in Pseudomonas aeruginosa (15.7% vs 25.0%, P<0.001), 3rd generation cephalosporin resistance in Escherichia coli (11.5% vs 17.8%, P<0.001) as well as Klebsiella pneumoniae (1.6% vs 4.4%, P<0.001), and ampicillin resistance in Haemophilus influenzae (2.4% vs 3.9%, P<0.001). After 2015, however, the proportion of methicillin-resistant and vancomycin-intermediate Staphylococcus aureus was low. In this study, in-hospital mortality was comparable among patients with resistance to the three WHO priority pathogen types: critical (5.9%), high (3.9%), and medium (3.8%), and no significant change was observed between two phases in each category. However, significant interactions for in-hospital mortality were observed in subgroup analyses between “critical priority” AMR and the presence of comorbid conditions, such as chronic kidney disease or diabetes mellitus.

Conclusions

To implement better antimicrobial stewardship policies and practices, local priority pathogens and “high-risk” patients for in-hospital death need to be acknowledged and evaluated periodically.
Do high house prices promote the development of China’s real economy? Empirical evidence based on the decomposition of real estate price
Authors: Fan Wei , He Yun , Hao Liang , Wu Fan
Published: January 2024

Moderate rising of house prices are beneficial to the economic development. However, over high house prices worsen the economic distortions and thus hinder the development of the real economy. We use the stochastic frontier models to calculate the fundamental value in the housing in Chinese large and medium cities, and then obtain indexes which could measure the house prices’ deviations from the fundamental value. With the macroeconomic data in the city-level, this paper empirically investigates the effects of the house prices’ deviations on macro-economic variables like consumption, investment and output. The study reveals that the housing bubble exists in most Chinese cities, and first-tier cities fare the worst. House prices over the fundamental value, which could increase the scale of real estate investment, bring adverse impacts on GDP, as it causes declining civilian consumption and discourages real economy’s investment and production. The encouragement and the discouragement on macroeconomy caused by house prices’ deviation from its basic value take turns to play a key role in the process of China’ eco-nomic growth. In the early stage of China’s economic growth, the encouragement effect predominates. As urbanization and industrialization gradually upgrade to a higher level, the discouragement effect takes charge.
How social organizations participate in social governance in China: Official media’s attention distribution analysis (1949–2021)
Authors: Liu Huangjuan , Ma Fujun , Chen Xiaoman
Published: January 2024

The attitude of the Chinese government towards social organizations (SOs) is crucial, as it affects the management rule and development tendency of SOs. To research the rule of SOs’ participation in social governance in China, this study used a new historical perspective, the institutional development perspective, to conduct its exploration. This perspective provides an accurate measure of the reality of the SOs’ participation, as it involves a mixed research methodology using continuous data from 73 years of reports and content mining, as well as topic clustering analysis to reveal a macroscopic and multi-line picture. Using a co-word analysis of hundreds of reports, from 1949–2021, in the People’s Daily, an official newspaper of the Communist Party of China, this study quantified changes in intensity, emotion, and content regarding social organization participation in social governance through topic distribution. Three trends were revealed: (1) “social-oriented character” and “organized-oriented character” were identified during the change in SOs; (2) the extent of being managed gradually strengthened and shifted from the Communist Youth League of China to the Community Party of China; (3) the goals of SOs shifted from general to innovated function in special charitable organizations. The institutional development perspective can complement the focus event perspective, including a new method, co-word analysis, to examine official Chinese media and validate the Administrative Absorption of Society (AAS) theory by identifying two lines of topic clustering trends. The attention distribution analysis in official media from an institutional development perspective can help explore the role of official media reports in analyzing the allocation of national attention and provide new analytical methods for big data mining to establish the social and organizational natures of SOs to optimize their roles. It offers a basis for modern social governance policy innovation in China.
A warm-up strategy with or without voluntary contraction on athletic performance, lower-leg temperature, and blood lactate concentration
Authors: Lee Seunghee , Lim Junhyeong , Park Jihong
Published: January 2024

It is unclear whether temperature-related warm-up effects can be accomplished by passive warm-up (e.g., by external heat). Therefore, this study compared the effects of two different warm-up protocols with and without voluntary contraction on subsequent sprinting and jumping performance. Eighteen healthy male collegiate students (23.3 ± 2.4 years, 173.8 ± 7.2 cm, 70.5 ± 9.3 kg) randomly experienced 10 min of active (jogging on a treadmill; belt speed: 9.0 km/h at a 1% incline) and passive warm-up (lying down in the warm-up chamber; inner ambient temperature set at 35°C) protocols, followed by ten sets of intermittent exercises in two separate sessions. Athletic performance, lower-leg muscle temperature, and blood lactate concentration were statistically compared using analysis of variance with Tukey-Kramer post-hoc comparisons. Cohen’s d effect sizes (ES) were also calculated. There was no warm-up protocol effect over time on 20 m sprint times (condition × time: F9,323 = 1.26, p = 0.25). Maximal vertical jump heights were different (condition × time: F9,323 = 2.0, p = 0.04) such that subjects who performed the active warm-up protocol jumped higher (51.4 cm) than those who did the passive warm-up (49.2 cm, p = 0.04). There was a warm-up protocol effect over time on lower-leg muscle temperature (condition × time: F12,425 = 13.99, p<0.0001) in that there was a 5.5% and 5.8% increase after active (32.8 to 34.6°C, ES = 2.91) and passive (32.9 to 34.9°C, ES = 3.28) warm-up protocols, respectively. Blood lactate concentration was different (condition × time: F2,85 = 3.61, p = 0.03) since the values at the post-warm-up measurements were different between warm-up conditions (active: 4.1 mmol/L; passive: 1.5 mmol/L, p = 0.004, ES = 1.69). Subsequent sprint and jump performance did not differ between the duration- and muscle temperature-matched active and passive warm-up protocols. Non-thermal effects from the warm-up activity may be minimal for sprinting and jumping performance in recreationally active males.