bluuebunny/crossref_metadata_2025 huggingface dataset:
A novel AuNP colorimetric sensor based on a polyadenine probe for ultra-sensitive detection of Ag+
Authors: Li Dandan , Wen Qilin , Zhou Yanyu , Huang Guidan , Xi Huai , Zhang Lianming , Li Ziyuan , Zhu Wenyuan
Published: December 2022

Silver(i) ions (Ag+) are harmful to humans and can be bioaccumulated in organisms.
A bioorthogonal chemistry approach to detect the K1 polysialic acid capsule in Escherichia coli
Authors: Rigolot Vincent , Rossez Yannick , Biot Christophe , Lion Cédric
Published: December 2022

A metabolic oligosaccharide engineering method that enables bioorthogonal labelling of the K1 capsule expressed by pathogenic Escherichia coli strains associated with neonatal meningitis and sepsis.
Collective plasmonic resonances enhance the photoluminescence of rare-earth nanocrystal films processed by ultrafast annealing
Authors: Cabello-Olmo Elena , Higashino Makoto , Murai Shunsuke , Tanaka Katsuhisa , Lozano Gabriel , Míguez Hernán
Published: December 2022

Rapid thermal annealing allows ultrafast processing of rare-earth nanocrystal thin films to achieve close-to-one photoluminescence quantum yield while preserving the transparency of the layers, which further enables their integration with photonic architectures.
Structurally diverse G-quadruplexes as the noncanonical nucleic acid drug target for live cell imaging and antibacterial study
Authors: Zheng Bo-Xin , Yu Jie , Long Wei , Chan Ka Hin , Leung Alan Siu-Lun , Wong Wing-Leung
Published: December 2022

The recent advances in G-quadruplex-selective ligands in the fields of live cell imaging, chemical biology and therapeutic prospects against bacterial infections.
A dinuclear copper(ii) complex with photoswitchable catechol oxidation activity
Authors: Marcon Michela , Crespi Stefano , Pielmeier Andreas , König Burkhard
Published: December 2022

Photoswitching of a catechol oxidase mimic: irradiation brings the Cu2+ centres closer together, enhancing catalytic activity.
Regiocontrolled halogen dance of 2,5-dibromopyrroles using equilibrium between dibromopyrrolyllithiums
Authors: Okumi Tatsuki , Mori Atsunori , Okano Kentaro
Published: December 2022

A regiocontrolled halogen dance of 2,5-dibromopyrroles provides isomeric dibromopyrroles using an N,N-dimethylsulfamoyl group that facilitates interconversion of 2,3- and 2,4-dibromopyrrolyllithiums.
Investigating the potential of hydroxyethylamino-di(methylene phosphonic acid) in inhibiting gypsum crystallization
Authors: Rabizadeh Taher
Published: December 2022

HEMPA has the potential to mitigate gypsum scaling through chelation with Ca2+in solution and adsorption onto and incorporation into the crystals.
Influence of interfacial energy on the growth of SiC single crystals from high temperature solutions
Authors: Wang Guobin , Sheng Da , Li Hui , Zhang Zesheng , Guo Lingling , Guo Zhongnan , Yuan Wenxia , Wang Wenjun , Chen Xiaolong
Published: December 2022

Al addition modifies the interfacial energy of SiC/solution during the growth of SiC single crystals via TSSG, and is beneficial to smoothing the growth surface, improving the crystalline quality, stabilizing the 4H polytype, and increasing the growth rate.
Extracting, quantifying, and comparing dynamical and biomechanical properties of living matter through single particle tracking
Authors: Scott Shane , Weiss Matthias , Selhuber-Unkel Christine , Barooji Younes F. , Sabri Adal , Erler Janine T. , Metzler Ralf , Oddershede Lene B.
Published: December 2022

A panoply of new tools for tracking single particles and molecules has led to novel insights into physical properties of living matter governing cellular development and function, health and disease.
Structural basis for the mutation-induced dysfunction of the human IL-15/IL-15α receptor complex
Authors: Batool Zahida , Qureshi Urooj , Mushtaq Mamona , Ahmed Sarfaraz , Nur-e-Alam Mohammad , Ul-Haq Zaheer
Published: December 2022

In silico strategies offer a reliable, fast, and inexpensive, way compared to the clumsy in vitro approaches to boost understanding of the effect of amino acid substitution on the structure and consequently the associated function of proteins.
Investigating the hydrolysis of cryogenically layered molybdenum hexafluoride through a disordered hydrogen-bonded network
Authors: McNamara Louis , Waldron Abigail , Thomas Michael , Jones Willis , O’Rourke Patrick , Darrell Simmons , Strange Fessler K. Alicia
Published: December 2022

Molybdenum hexafluoride (MoF6) is used as a non-radioactive substitute for uranium to study the hydrolysis of metal hexafluorides.
Trapping of single diffusing particles by a circular disk on a reflecting flat surface. Absorbing hemisphere approximation
Authors: Dagdug Leonardo , Berezhkovskii Alexander M. , Bezrukov Sergey M.
Published: December 2022

Sample trajectories of a particle starting atr0.
Unraveling the low-temperature activity of Rh–CeO2 catalysts in CO oxidation: probing the local structure and Red-Ox transformation of Rh3+ species
Authors: Fedorova Elizaveta A. , Kardash Tatyana Yu. , Kibis Lidiya S. , Stonkus Olga A. , Slavinskaya Elena M. , Svetlichnyi Valery A. , Pollastri Simone , Boronin Andrei I.
Published: December 2022

We established the structural features of Rh single atom and RhOx clusters in CeO2, their Red-Ox reversibility and low temperature CO oxidation activity.
Synchrotron radiation photoemission spectroscopy of the oxygen modified CrCl3 surface
Authors: Kazim S. , Mastrippolito D. , Moras P. , Jugovac M. , Klimczuk T. , Ali M. , Ottaviano L. , Gunnella R.
Published: December 2022

We investigate the experimentally challenging CrCl3 surface by photon energy dependent photoemission (PE).
Enzyme–substrate interactions in orotate-mimetic OPRT inhibitor complexes: a QM/MM analysis
Authors: Kumar Shashi , Rao N. N. Subrahmanyeswara , Reddy K. S. S. V. Prasad , Padole Manjusha C. , Deshpande Parag A.
Published: December 2022

QM/MM analysis of orotate-mimetic inhibitors of orotate phosphoribosyltransferase revealed 4-Hydroxy-6-methylpyridin-2(1H)-one be the best inhibitor among the tested ones for the inhibition of OPRT action.
Recent advances in fluorescent and colorimetric chemosensors for the detection of chemical warfare agents: a legacy of the 21st century
Authors: Kumar Vinod , Kim Heejeong , Pandey Bipin , James Tony D. , Yoon Juyoung , Anslyn Eric V.
Published: December 2022

This review highlights recently reported optical molecular sensors for the sensing of Chemical Warfare Agents (CWAs) including nerve agents, blister agents, blood agents, and other toxicants.
Finite perovskite hierarchical structures via ligand confinement leading to efficient inverted perovskite solar cells
Authors: Huang Yanchun , Yan Kangrong , Niu Benfang , Chen Zeng , Gu Emely , Liu Haoran , Yan Buyi , Yao Jizhong , Zhu Haiming , Chen Hongzheng , Li Chang-Zhi
Published: December 2022

Finite 2D/3D hierarchical perovskites are effectively constructed via interfacial ligand confinement to obtain efficient and stable inverted perovskite solar cells and modules.
Self-propelled Janus magnetic micromotors as peroxidase-like nanozyme for colorimetric detection and removal of hydroquinone
Authors: Zhang Xiaolei , Liu Bin , Wei Tao , Liu Zongming , Li Jinkai
Published: December 2022

A Janus micromotor-assisted dual-function platform through a novel and facile method was designed and fabricated for sensitive detection and rapid degradation of hydroquinone in water.
Effect of liquid confinement on regioselectivity in the hydrosilylation of alkynes with cationic Rh(i) N-heterocyclic carbene catalysts
Authors: Panyam Pradeep K. R. , Buchmeiser Michael R.
Published: December 2022

A liquid confinement is created using an ionic liquid containing a Rh–N-heterocyclic carbene catalyst, all supported on a polymeric monolithic support. Alkyne hydrosilylation reactions can be run under biphasic conditions with high β-(Z) selectivity.
On the mechanism of intermolecular nitrogen-atom transfer from a lattice-isolated diruthenium nitride intermediate
Authors: Cosio Mario N. , Alharbi Waad S. , Sur Aishanee , Wang Chen-Hao , Najafian Ahmad , Cundari Thomas R. , Powers David C.
Published: December 2022

Computational studies indicate nitrogen-atom transfer at lattice-confined diruthenium sites proceeds by an H-atom abstraction, radical rebound mechanism and corroborate available porosity-dependent kinetic isotope effects.
Unveiling the potential of deep eutectic solvents to improve the conformational and colloidal stability of immunoglobulin G antibodies
Authors: Dhiman Diksha , Marques Ana S. C. , Bisht Meena , Tavares Ana P. M. , Freire Mara G. , Venkatesu Pannuru
Published: December 2022

Deep Eutectic solvent as a suitable solvent system to design a final pharmaceutical formulation of immunoglobulin G antibodies.
The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhancesT1-weighted magnetic resonance imaging contrast
Authors: Liu Jianping , Li Li , Zhang Run , Xu Zhi Ping
Published: December 2022

Magnetic resonance imaging (MRI) is one key technology in modern diagnostic medicine.
Nitrogen-doped BiOBr nanosheets with preferentially exposed (102) facets enhanced visible-light photoreactivity
Authors: Li Guangbi , Yang Jie , Yang Xinhui , Liu Mila , Liu Bingyan , Li Zhuolan , Bao Kexin , Wang Yurong , Wang Zhiwei , Zhou Huan
Published: December 2022

Schematics of the photocatalytic degradation of RhB.
A multifunctional strategy of two-dimensional WS2modified absorbers for efficient planar perovskite solar cells
Authors: Sun Qinghua , Hu Wanting , Yu Miao , Wang Fengyou , Liu Xiaoyan , Yang Lihua , Liu Huilian , Fan Lin , Yang Lili
Published: December 2022

A novel WS2modified perovskite was constructed. Synergistic effects of WS2on the crystallization kinetics and charge behaviors were proposed.
Copper-catalyzed synthesis of benzo[4,5]thiazolo[3,2-a]indoles from elemental sulfur and 1-(2-iodophenyl)-1H-indoles
Authors: Wang Zongkang , Yuan Yang , Jin Shuxin , Wang Ye , Gu Yingge , Wang Chengyu , Li Yanzhong
Published: December 2022

This is the first example of making benzo[4,5]thiazolo[3,2-a]indoles from cheap and odourless elemental sulfur.
Strongly enhanced piezocatalysis of BiFeO3/ZnO heterostructure nanomaterials
Authors: Zhang Qichang , Jia Yanmin , Chen Jing , Wang Xiaoxing , Zhang Luohong , Chen Zhi , Wu Zheng
Published: December 2022

BiFeO3/ZnO heterostructures, with a strongly enhanced piezocatalytic dye decomposition performance, offer a promising option to treat wastewater through collecting environmental vibration energy.
Quadratic nonlinear optical response of composite polymer materials based on push–pull quinoxaline chromophores with various groups in the aniline donor moiety
Authors: Kalinin Alexey A. , Islamova Liliya N. , Sharipova Sirina M. , Fazleeva Guzel M. , Gaysin Adel I. , Shmelev Artemiy G. , Simanchuk Andrey E. , Turgeneva Snezhana A. , Sharipova Anastasiya V. , Mukhtarov Anvar S. , Vakhonina Tatyana A. , Fominykh Olga D. , Mikerin Sergey L. , Balakina Marina Yu.
Published: December 2022

Novel D–π–A–π–A′ chromophores with different substituents in the donor moiety were synthesized and NLO coefficients for composite polymer materials doped with them were measured.
Yttrium-preintercalated layered manganese oxide as a durable cathode for aqueous zinc-ion batteries
Authors: Wu Tzu-Ho , Lin Ya-Qi , Huang Jian-Xue
Published: December 2022

Preintercalated Y3+ in layered MnO2 can elaborately regulate the electronic structure, boost electrochemical activity, and render better electrochemical reversibility of MnO2, leading to enhanced energy storage in aqueous Zn-ion batteries.
Functionalized polymer modified buried interface for enhanced efficiency and stability of perovskite solar cells
Authors: Zou Hanjun , Bi Huan , Chen Yongheng , Guo Mengna , Hou Wenjing , Su Pengyu , Zhou Kai , Yang Chuanyao , Gong Xiangnan , Xiao Li , Liu Li
Published: December 2022

A new interfacial polymer material named povidone-iodine was reported. Due to the reduced defect density and improved interface contact, ultimately, we achieved attractive efficiency and considerable long-term stability.
Metal-free homo-/cross-anion–cation coupling of cyclic diaryl λ3-bromanes
Authors: Wang Yiwen , Tian Ya-Nan , Ren Shiyan , Zhu Ruijie , Huang Bin , Wen Yanqiong , Li Shiqing
Published: December 2022

The homo anion–cation coupling of cyclic diaryl λ3-bromanes/diarylbrominiums has been disclosed for the first time. Moreover, metal-free cross-coupling of cyclic diarylbrominiums with alcohols, phenols, and water has been developed.
Base-promoted synthesis of tetrasubstituted alkenylboronates from propargyl amines and B2pin2via dual 1,4-metallate shift and B–N elimination
Authors: Liu Kang , Jin Shengnan , Song Qiuling
Published: December 2022

An efficient approach to synthesize tetrasubstituted alkenylboronates via a cascade borylation/B–N elimination of propargyl amines and B2pin2 is disclosed.
Enantioselective N-heterocyclic carbene-catalyzed rearrangement of enol ε-lactones
Authors: Qiu Ye , Liang Zhi-Qin , Chen Kun-Quan , Dai Lei , Ye Song
Published: December 2022

The enantioselective N-heterocyclic carbene-catalyzed rearrangement of enol ε-lactones was developed for the construction of bicyclic β-lactones.
Correction: Realization of a piezoelectric quantum spin Hall phase with a large band gap in MBiH (M = Ga and In) monolayers
Authors: Wang Y. H. , Lei S. Y. , Xu F. , Chen J. , Wan N. , Huang Q. A. , Sun L. T.
Published: December 2022

Correction for ‘Realization of a piezoelectric quantum spin Hall phase with a large band gap in MBiH (M = Ga and In) monolayers’ by Y. H. Wang et al., J. Mater. Chem. A, 2022, 10, 25683–25691, https://doi.org/10.1039/D2TA04206A.
Protein targeting by the itaconate family in immunity and inflammation
Authors: Day Emily A. , O'Neill Luke A.J.
Published: December 2022

Immune cells are metabolically plastic and respond to inflammatory stimuli with large shifts in metabolism. Itaconate is one of the most up-regulated metabolites in macrophages in response to the gram negative bacterial product LPS. As such, itaconate has recently been the subject of intense research interest. The artificial derivatives, including 4-Octyl Itaconate (4-OI) and Dimethyl Itaconate (DI) and naturally produced isomers, mesaconate and citraconate, have been tested in relation to itaconate biology with similarities and differences in the biochemistry and immunomodulatory properties of this family of compounds emerging. Both itaconate and 4-OI have been shown to modify cysteines on a range of target proteins, with the modification being linked to a functional change. Targets include KEAP1 (the NRF2 inhibitor), GAPDH, NLRP3, JAK1, and the lysosomal regulator, TFEB. 4-OI and DI are more electrophilic, and are therefore stronger NRF2 activators, and inhibit the production of Type I IFNs, while itaconate inhibits SDH and the dioxygenase, TET2. Additionally, both itaconate and derivates have been shown to be protective across a wide range of mouse models of inflammatory and infectious diseases, through both distinct and overlapping mechanisms. As such, continued research involving the comparison of itaconate and related molecules holds exciting prospects for the study of cysteine modification and pathways for immunomodulation and the potential for new anti-inflammatory therapeutics.
Research on energy‐saving virtual machine migration algorithm for green data center
Authors: Li Huxiong , Liu Jun , Zhou Qingbiao
Published: December 2022

The cloud computing center can dynamically respond to various needs, schedule computing resources, and provide users with convenient IT services. As the demand for cloud computing services continues to increase, the scale of the data center is getting larger and larger, and the problem of high energy consumption of equipment is becoming more and more prominent. Therefore, building a green data center is key to ensuring the development of the technology industry. Virtual machine online migration technology has been widely used in energy consumption management, which plays an important role in the energy‐saving management of large‐scale data centers. Considering the problem of energy consumption in a multi‐data center environment, a cross‐data center virtual machine migration strategy is proposed, EVMA. First, the target data center of the virtual machine migration is determined according to the bandwidth between data centers, and then the overload host and virtual machine selection strategy is determined according to the historical CPU load. The experimental results showed that the algorithm had a good performance in reducing the energy consumption of the data center and ensuring the quality of service.
Conductor temperature monitoring for the fully insulated busbar prefabricated joint considering contact resistance
Authors: Tang Liezheng , Ruan Jiangjun , Chen Rou , Zhou Guohua
Published: December 2022

The fully insulated busbar system, which has been extensively used in the industry, contains a large number of joints due to its limited length, and thus it is prone to overheating failure caused by poor contact. Taking the uncertainty of contact resistance into account, this paper presents an indirect approach to monitor the conductor temperature for the fully insulated busbar prefabricated joint using the busbar surface temperatures. The model is composed of radial direction temperature calculation (RDTC) in the busbar and axial direction temperature calculation (ADTC) in the conductor. The equivalent thermal resistance of joint is defined to characterize the influence of contact resistance, based on which RDTC and ADTC are corrected by an iterative method. The temperature rise test of the prefabricated joint was carried out. When the contact state is normal, the transient and steady‐state error is within 4 and 1 K, respectively. When the contact state is abnormal, the steady‐state error under rated current is less than 5 K, and the transient error with the step load is about 10 K, which is thoroughly analyzed. From an engineering point of view, the proposed algorithm can effectively monitor the joint hotspot temperature and evaluate the contact state.
Axial and radial electromagnetic‐vibration characteristics of converter transformer windings under current harmonics
Authors: Jiang Peiyu , Zhang Zhanlong , Dong Zijian , Yang Yu , Pan Zhicheng , Deng Jun
Published: December 2022

The winding current harmonic content of converter transformer in operation is rich. However, affected by harmonics, the radial vibration characteristics are quite different from the power transformer, structural loosening and deformation caused by winding vibration are more prominent. Therefore, in view of the influence of current harmonics on axial and radial vibrations, this study builds a 3D winding electromagnetic vibration finite element simulation model, analyses the components and contents of current harmonics, compares the leakage flux and vibration distribution under the fundamental, harmonic and superimposed currents. The correlation relationship between the harmonic components and axial and radial vibration characteristics is obtained, and the vibration measurement test of ±800 kV converter transformer in operation is carried out to verify the correctness of the analysis method. The results show that the winding radial vibration amplitude will exceed the axial vibration affected by harmonics. More importantly, under the superposition of the fundamental, 5th and 7th harmonic current, the vibration contribution of the converter transformer tank is mainly radial vibration, and the vibration dominant frequency is shifted from 100 Hz under the fundamental current to 400 Hz.
Multi‐domain autonomous driving dataset: Towards enhancing the generalization of the convolutional neural networks in new environments
Authors: Khosravian Amir , Amirkhani Abdollah , Masih‐Tehrani Masoud , Yazdanijoo Alireza
Published: December 2022

In this paper, a large‐scale dataset called the Iran Autonomous Driving Dataset (IADD) is presented, aiming to improve the generalization capability of the deep networks outside of their training domains. The IADD focuses on 2D object detection and contains more than 97,000 annotated images, covering six common object classes in the field of autonomous vehicles. To improve the generalization of the models, a wide variety of driving conditions and domains, including the city and suburban road settings, adverse weather conditions, and various traffic flows, are presented in the IADD images. The results of exhaustive evaluations conducted on several state‐of‐the‐art convolutional neural networks reveal that not only the trained architectures have performed successfully on test data of the IADD, but also they have upheld high precision in the assessments of generalization capability. In order to challenge the models, broad range of simulations have been performed in the CARLA software environment; which due to the synthetic nature of the simulated images, severe domain shifts have been observed between the CARLA and the IADD. Also, the cross‐domain evaluation results have confirmed the efficacy of the IADD in enhancing the generalization ability of the deep learning models. The dataset is available in: https://github.com/ahv1373/IADD
.
Phasor data concentrator placement in phasor measurement unit networks considering communication channel uncertainty and failure
Authors: Dehghani Maryam , Vafamand Navid
Published: December 2022

One challenge in Wide Area Measurement System is to design a reliable network which assures data availability. The availability of data in Phasor Measurement Unit (PMU) networks depends on two factors: 1‐Reliable data measurements which depend on performance of PMUs and transmission branches, 2‐Reliable data transmission which depends on the reliability of communication networks used to transfer data from PMUs to Phasor Data Concentrators (PDCs) and control centre. The reliability of data transmission can be improved by choosing proper locations for PDCs. In this paper, a novel approach for PDC placement is proposed based on two pre‐defined indices; observability reliability and Loss Of Data Expectation (LODE). In the proposed method, the probability of regional communication networks' failure and the uncertainty of failure data for all components are also included in the calculation of these two indices to achieve more realistic results. To handle uncertainty, fuzzy membership functions are obtained for repair time and failure rate of all components, and a fuzzy Monte Carlo method is presented to evaluate both indices for each possible PDCs' location. The minimum LODE is used to find the best locations for PDCs. The proposed method is investigated for three sample systems which prove the system efficacy.
The height of convective plumes in the red supergiant μ Cep
Authors: López Ariste A. , Wavasseur M. , Mathias Ph. , Lèbre A. , Tessore B. , Georgiev S.
Published: December 2022

Aims. We seek to understand convection in red supergiants and the mechanisms that trigger the mass loss from cool evolved stars.

Methods. Linear spectropolarimetry of the atomic lines of the spectrum of μ Cep reveals information well outside the wavelength range expected from previous models. This is interpreted as structures in expansion that are visible in the front hemisphere and sometimes also in the back hemisphere. We model the plasma distribution together with its associated velocities through an inversion algorithm to fit the observed linear polarization.

Results. We find that supposing the existence of plasma beyond the limb rising high enough to be visible above it can explain the observed linear polarization signatures as well as their evolution in time. From this we are able to infer the geometric heights of the convective plumes and establish that this hot plasma rises to at least 1.1 R*.

Conclusions. μ Cep appears to be in an active phase in which plasma rises often above 1.1 R*. We generalize this result to all red supergiants in a similarly evolved stage, which at certain epochs may easily send plasma to greater heights, as μ Cep appears to be doing at present. Plasma rising to such heights can easily escape the stellar gravity.
Exotic states in the quarkonium sector — status and perspectives
Authors: Yuan Chang-Zheng
Published: December 2022

The discovery of hadronic states beyond the conventional two-quark meson and three-quark baryon picture in the last two decades is one of the most amazing accomplishments in fundamental physics research. Many experiments contributed to this field despite of the original goals of the design. We review the experimental progress on the study of the quarkoniumlike states — states with at least one heavy quark-antiquark pair and possible light quarks, also known as XYZ states. We give a general review and then focus on the new experimental results on the X(3872) and its bottom-quark partner Xb, the X(3960), the Y(4260), Y(4500), Y(4660), and Y(10750), and the charged charmoniumlike Zc and Zcs states. The observations suggest that we did observe hadronic molecules and we also observed hadronic states with some other quark configurations. Possible further studies at the existing and future facilities are briefly discussed.
Excited States of “Elementary” Particles in Gauge-Higgs Theories
Authors: Greensite Jeff , Matsuyama Kazue
Published: December 2022

We show that the gauge and scalar fields which surround static ions in the Ginzburg-Landau model of superconductivity have a spectrum of excitations which are potentially observable. This ties in with earlier results along these lines found in a variety of gauge Higgs theories. Excitations of this type would appear as a mass spectrum of the “elementary” particles in the theory.
Zooming in on Multiquark Hadrons within QCD Sum-Rule Approaches
Authors: Lucha Wolfgang , Melikhov Dmitri , Sazdjian Hagop
Published: December 2022

Aiming at self-consistent descriptions of multiquark hadrons (such as tetraquarks, pentaquarks, hexaquarks) by means of QCD sum rules, we note that the totality of contributions to two-point or three-point correlation functions that involve, respectively, either two or just a single operator capable of interpolating the particular multiquark under study can be straightforwardly disentangled into two disjoint classes defined by unambiguously identifiable members. The first is formed by so-called multiquark-phile contributions which indeed might support multiquarks. In the case of flavour-exotic tetraquarks, by definition composed of four (anti–) quarks of mutually different flavours, a tetraquark-phile contribution has to exhibit two or more gluon exchanges of appropriate topology. The second consists of contributions evidently not bearing any relation to multiquarks; these must be discarded when studying multiquarks by QCD sum rules. The first class only should enter the “multiquark-adequate” QCD sum rules for exotic hadrons.
Femtoscopy of the J/ψ-nucleon interaction
Authors: Krein Gastão
Published: December 2022

I discuss the prospects of using femtoscopy in high-energy protonproton and heavy-ion collisions to learn about the low-energy J/ψ-nucleon interaction. Femtoscopy is a technique that makes it possible to obtain spatiotemporal information on particle production sources at the femtometer scale through measurements of two-hadron momentum correlation functions. These correlation functions also provide information on low-energy hadron-hadron forces as final-state effects. In particular, such correlation functions give access to the forward scattering amplitude. One can express the forward amplitude as the product of the J/ψ chromopolarizability and the nucleon’s average chromoelectric gluon distribution, the latter being relevant to the problem of the origin of the nucleon mass. I will present the results of a recent study using the information on the J/ψ-nucleon interaction from lattice QCD simulations to compute J/ψ-nucleon correlation functions. The calculated correlation functions show clear sensitivity to the final-state interaction. I conclude discussing open issues regarding the use of the effective range expansion formula to fit experimental data for small scattering lengths and large effective range parameters.
Open and hidden heavy flavor measurements at RHIC
Authors: Kosarzewski Leszek
Published: December 2022

Quarks of heavy flavors are useful tool to study quark-gluon plasma created in heavy-ion collisions. Due to their high mass and early production time, heavy quarks experience the entire evolution of the system created in these collisions. Open heavy flavor meson measurements are sensitive to the energy loss in the QGP, while quarkonia are sensitive to the temperature of the QGP as they dissociate because of Debye-like screening of color charges.

This presentation is a summary of the latest heavy flavor studies performed at RHIC. Results from both STAR and PHENIX experiments are presented, compared to theoretical calculations and the implications discussed.
Examination of subleading twist proton TMD gTν in the light-front quark-diquark model
Authors: Sharma Shubham , Kumar Narinder , Dahiya Harleen
Published: December 2022

We have examined the subleading twist T-even transverse momentum dependent parton distribution (TMD) gνT (x, p⊥2) for proton in the light-front quark-diquark model (LFQDM). For semi-inclusive deep inelastic scattering (SIDIS), we have decrypted the unintegrated quark-quark correlator and derived the explicit expression of the TMD gνT (x, p2⊥) by considering the both scalar and vector diquarks. The 2-D and 3-D plots of this TMD for both up and down quarks have been examined. Expression of TMD gνT (x, p2⊥) in the form of available results leading twist TMDs g⊥q1T (x, p⊥) and hq1(x, p⊥) has been provided. Plot of transverse momentum-dependent parton distribution function (TMDPDF) gνT (x) have also been provided.
ϕ meson properties in nuclear matter from dilepton spectra in a transport approach
Authors: Gubler Philipp , Bratkovskaya Elena , Song Taesoo
Published: December 2022

The current status of research related to the behavior of the ϕ meson in nuclear matter is reviewed. First, recent theoretical works based of QCD sum rules and effective theory approaches are discussed. Next, preliminary results of transport simulations of pA reactions, with the goal of reproducing the dilepton spectra of the KEK E325 experiment are presented.
Gravitational Waves from dark composite dynamics
Authors: Reichert Manuel , Wang Zhi-Wei
Published: December 2022

We discuss the stochastic gravitational-wave spectrum from dark confinement and chiral phase transitions in the early Universe. Specifically, we look at pure Yang-Mills theory for an arbitrary number of colours as well as SU(3) with quarks in different representations. We utilise thermodynamic Lattice data and map it to effective models, such as the Polyakov-loop and the PNJL model. This allows us to compute gravitational-wave parameters and the corresponding gravitational-wave signal. We compare the signal to future gravitational-wave observatories such as the Big Bang Observer and DECIGO.
The density of states method in Yang-Mills theories and first order phase transitions
Authors: Mason David , Lucini Biagio , Piai Maurizio , Rinaldi Enrico , Vadacchino Davide
Published: December 2022

Extensions of the standard model that lead to first-order phase transitions in the early universe can produce a stochastic background of gravitational waves, which may be accessible to future detectors. Thermodynamic observables at the transition, such as the latent heat, can be determined by lattice simulations, and then used to predict the expected signatures in a given theory. In lattice calculations, the emergence of metastabilities in proximity of the phase transition may make the precise determination of these observables quite challenging, and may lead to large uncontrolled numerical errors. In this contribution, we discuss as a prototype lattice calculation the first order deconfinement transition that arises in the strong SU(3) Yang-Mills sector. We adopt the novel logarithmic linear relaxation method, which can provide a determination of the density of states of the system with exponential error suppression. Thermodynamic observables can be reconstructed with a controlled error, providing a promising direction for accurate model predictions in the future.
Strongly Interacting Dark Matter from Sp(4) Gauge Theory
Authors: Zierler Fabian , Kulkarni Suchita , Maas Axel , Mee Seán , Nikolic Marco , Pradler Josef
Published: December 2022

The stable hadronic bound states in a hidden new non-Abelian gauge sector provide interesting candidates for strongly-interacting Dark Matter (DM). A particular example are theories in which DM is made up of dark pions which set the DM relic abundance through self-annihilation. One of the simplest realizations is Sp(4)c gauge theory with two Dirac fermions. We discuss its mesonic multiplets for degenerate and non-degenerate fermions, construct a low-energy effective theory and present lattice results for the pseudoscalar mesons and vector mesons.
Insights into the Molecular Genetic of Hemophilia A and Hemophilia B: The Relevance of Genetic Testing in Routine Clinical Practice
Authors: Pezeshkpoor Behnaz , Oldenburg Johannes , Pavlova Anna
Published: December 2022

Hemophilia A and hemophilia B are rare congenital, recessive X-linked disorders caused by lack or deficiency of clotting factor VIII (FVIII) or IX (FIX), respectively. The severity of the disease depends on the reduction of coagulation FVIII or FIX activity levels, which is determined by the type of the pathogenic variants in the genes encoding the two factors (F8 and F9, respectively). Molecular genetic analysis is widely applied in inherited bleeding disorders. The outcome of genetic analysis allows genetic counseling of affected families and helps find a link between the genotype and the phenotype. Genetic analysis in hemophilia has tremendously improved in the last decades. Many new techniques and modifications as well as analysis softwares became available, which made the genetic analysis and interpretation of the data faster and more accurate. Advances in genetic variant detection strategies facilitate identification of the causal variants in up to 97% of patients. In this review, we discuss the milestones in genetic analysis of hemophilia and highlight the importance of identification of the causative genetic variants for genetic counseling and particularly for the interpretation of the clinical presentation of hemophilia patients.
Isolated Maternal Hypothyroxinemia May be Associated with Insulin
Requirement in Gestational Diabetes Mellitus
Authors: Topaloğlu Ömercan , Uzun Mehmet , Topaloğlu Seda Nur , Sahin Ibrahim
Published: December 2022

An insulin regimen may be necessary for about 30% of the patients with
gestational diabetes mellitus (GDM). We aimed to investigate the association of
free T4(fT4) levels with insulin requirement in pregnant women with GDM. We
included pregnant women whose TSH levels were within the normal range and who
were diagnosed with GDM, and excluded patients with thyroid dysfunction, chronic
illnesses, or any previous history of antithyroid medication, levothyroxine, or
antidiabetic medication use. The diagnosis and treatment of GDM were based on
American Diabetes Association guidelines. Demographic features, previous history
of GDM and gestational hypertension were recorded. Baseline (at diagnosis of
GDM) fasting blood glucose, HbA1c, TSH, fT4, and fT3 levels were analyzed. We
grouped the patients according to their baseline fT4 levels: isolated maternal
hypothyroxinemia (IMH) (group A) vs. in the normal range (group B). We grouped
those also based on insulin requirement in 3rd trimester. Of the patients
(n=223), insulin requirement was present in 56, and IMH in 11. Insulin
requirement was more frequent in group A than in group B (p=0,003).
HbA1c (≥47,5 mmol/mol) and fT4 level (lower than normal
range) were positive predictors for insulin requirement (OR:35,35,
p=0,001; and OR:6,05, p=0,008; respectively). We showed that IMH
was closely associated with insulin requirement in GDM. Pregnant women with IMH
and GDM should be closely observed as regards to glycemic control. If supported
by future large studies, levothyroxine treatment might be questioned as an
indication for patients with GDM and IMH.
Preoperative Bladder Capacity Predicts Social Continence following Bladder Neck Reconstruction in Children Born with Exstrophy–Epispadias Complex
Authors: Bar-Yosef Yuval , Savin Ziv , Ekstein Margaret , Ben-David Reuben , Dekalo Snir , Bar-Yaakov Noam , Sofer Mario , Ben-Chaim Jacob
Published: December 2022

Introduction The aim of the study is to review the continence and volitional voiding rate in a single center cohort of exstrophy–epispadias patients following Young-Dees-Leadbetter bladder neck reconstruction and to explore factors which predict continence.

Materials and Methods Children who underwent Young-Dees-Leadbetter bladder neck reconstruction as a final stage of repair in a large single low-volume center in a small-population country between 1997 and 2019 were included. Demographic and clinical details were extracted from the patients' charts. The primary end point was continence and volitional voiding. Patients were categorized as incontinent, socially continent (daytime dry intervals > 3 hours, wet nights) and fully continent (daytime dry intervals > 3 hours, dry nights).

Results The study cohort included 27 patients whose median age at reconstruction was 5 years, and median follow-up was 7.8 years (interquartile range [IQR] 6–11.2). The cohort included 24 classic exstrophy patients (89%, 17 males and 7 females) and 3 isolated complete epispadias patients (11%, 1 male and 2 females). Nine (33%) patients achieved full continence and social continence was achieved by nine (33%) patients, for an overall social continence rate of 67%. Preoperative bladder capacity of 110 mL or more was associated with achieving social continence (odds ratio = 6.4, p = 0.047). The overall volitional voiding rate was 67%.

Conclusion Young-Dees-Leadbetter bladder neck reconstruction yielded rates of 33% for full continence and 67% for social continence and volitional voiding. These rates are comparable to those of large high-volume centers. A preoperative capacity of 110 mL or more was the sole predictor of social continence.
Congenital Duodenal Obstruction: National Trends in Management and Outcomes during the Last Quarter of a Century in Norway
Authors: Treider Martin , Granheim Sturla , Engebretsen Anders Hauge , Pripp Are Hugo , Røkkum Henrik , Skari Hans , Sæter Thorstein , Bjørnland Kristin
Published: December 2022

Introduction During the last quarter of a century, new surgical techniques in neonates have been introduced, and neonatal intensive care has developed. Few studies have explored the implementation of new techniques and if outcomes in neonates undergoing gastrointestinal surgery have improved in the last decades. Therefore, this study aimed to investigate possible changes in postoperative outcomes and surgical techniques in all neonates operated for congenital duodenal obstruction (CDO) 1995 to 2020 in Norway.

Material and Methods This is a national multicenter retrospective study of all neonates undergoing surgery for CDO in Norway from 1995 to 2020. Results from three periods (1995–2003, 2004–2012, and 2013–2020) were compared. The study was approved by the local data protection officers (2020/13386) and (2020/15125).

Results We included 186 patients: 41 in period 1 (1995–2003), 83 in period 2 (2004–2012), and 62 in period 3 (2013–2020). Seventy (38%) neonates had Down syndrome and 104 (62%) had additional malformations/disorders. Birth weight, gender, frequency of Down syndrome, and other malformations/disorders did not differ between the three periods. We observed an increased rate of prenatal diagnosis throughout the study period (p < 0.001). The only change in surgical technique was the increased use of transanastomotic feeding tubes (p < 0.001). Length of stay, postoperative complication rate, days with parenteral nutrition, and 30-day mortality rate were stable over time.

Conclusion Perioperative treatment and postoperative outcomes in neonates with CDO have been surprisingly unchanged during the last quarter of a century. Only an increased rate of prenatal diagnosis and more frequent use of transanastomotic feeding tubes were observed.
Transient Recurrent Laryngeal Nerve Palsy after Interventional Therapy
Authors: Mandilaras Guido , Happel Christoph M. , Funk Christoph M. , Haas Nikolaus A. , Freund Matthias , Fischer Marcus
Published: December 2022

Background Hoarseness due to laryngeal nerve injury is a known complication after cardiothoracic surgery involving the aortic arch. However, this complication is only rarely reported after catheter interventions.

Results In this article we present the unusual case of a left-sided vocal cord paralysis in four patients after primary stenting of a re-coarctation, re-dilatation of a stented coarctation, a primary stenting of the left pulmonary artery (LPA), and prestenting for percutaneous pulmonary valve implantation with dilation of the LPA. After implanting bare metal stents, it is common practice, whilst contemplating the diameters of the adjacent structures, to optimize the stent diameter in a two-step procedure and dilate the stent until a maximum diameter is achieved and there is no residual gradient after applying this technique. Four of our patients experienced hoarseness after the intervention and a vocal cord paralysis was diagnosed. Angiography revealed no signs of extravasation or dissection. Clinical symptoms improved over the course of the following 6 months; patients with interventions at the aortic arch showed a complete remission, patients with procedures involving the LPA showed only mild regression of the symptoms.

Conclusion To our knowledge, this complication (Ortner's syndrome, cardiovocal syndrome) after such interventions has rarely been reported before. Although a rare complication, the recognition of these symptoms may support colleagues in managing affected patients. In addition, awareness for hoarseness after interventional therapies and systematic screening for this complication might help to identify patients at risk in the future.
Chiral Phosphoric Acid Catalyzed Asymmetric Cycloadditions: from Alkenes to Alkynes
Authors: Wang Liu-Yang , Yang Lan , Chen Jie , Zhou Ling
Published: December 2022

Organocatalytic asymmetric cycloaddition reactions are the foundation for the construction of important cyclic molecules in synthetic chemistry and biochemistry. As a result, organic catalysts, in particular chiral phosphoric acid, entice researchers from all over the world to design and develop asymmetric cycloaddition reactions. In this Account, we discuss CPA-catalyzed [3+2] and [4+2] cycloaddition of alkenes and some further transformations from the cycloadducts, as well as several mechanisms related to these cycloadditions. All kinds of enantioenriched carbocycles and heterocycles with stereogenic centers could be synthesized efficiently. Recent advances in CPA-catalyzed cycloaddition of alkynes to generate axially chiral compounds are also discussed.

1 Introduction

2 CPA-Catalyzed [3+2] Cycloaddition of Alkenes

3 CPA-Catalyzed [4+2] Cycloaddition of Alkenes

4 CPA-Catalyzed Cycloaddition of Alkynes

5 Conclusions
Ruthenium-Catalyzed Regioselective Synthesis of C3-Alkylated Indoles Following Transfer Hydrogenation or Borrowing Hydrogen Strategy
Authors: Zhou Xiao-Yu , Chen Xia
Published: December 2022

By employing either borrowing hydrogen or transfer hydrogenation strategy, two straightforward [Ru(p-cymene)Cl2]2-catalyzed methods for regioselective synthesis of C3-alkylated indoles have been developed, utilizing alcohols as H atom donors or alkylating agents. The developed catalytic system could accommodate a broad substrate scope including primary/secondary aliphatic alcohols and substituted indoles, and in most cases providing good yields. Notable features of the developed system include high-activity, easy operation, and air atmosphere.
Effects of Growth Hormone on Muscle and Bone in Female Mice: Role of Follistatin
Authors: Ohira Takashi , Kawao Naoyuki , Takafuji Yoshimasa , Mizukami Yuya , Kaji Hiroshi
Published: December 2022

The interactions between muscle and bone are noted in the clinical relationships between sarcopenia and osteoporosis. Myokines secreted from the skeletal muscles play roles in muscle-bone interactions related to various physiological and pathophysiological states. Although numerous evidence suggests that growth hormone (GH) influences both muscle and bone, the effects of GH on the muscle-bone interactions have remained unknown. We, therefore, investigated the influences of GH administration for 8 weeks on muscle and bone, including myokine expression, in mice with or without ovariectomy (OVX). GH administration significantly increased muscle mass in the whole body and lower limbs, as well as tissue weights of the extensor digitorum longus (EDL) and soleus muscles in mice with or without OVX. Moreover, it markedly increased grip strength in both mice. As for femurs, GH administration significantly increased cortical thickness and area in mice with or without OVX. Moreover, GH significantly blunted the decrease in the ratio of bone volume to tissue volume at the trabecular bone in mice with OVX. GH administration significantly decreased follistatin mRNA levels in the EDL, but not the soleus, muscles in mice with or without OVX, although it did not affect the other myokines examined. However, GH administration significantly elevated serum follistatin levels in mice. In conclusion, this study indicates that GH administration increases skeletal muscle mass and grip strength and cortical and trabecular bone-related parameters obtained by micro-computed tomography analyses in mice. However, myokine regulation might not be critical for the effects of GH on muscle and bone.
Challenges and Strategies for Synthesizing Glutamyl Hydrazide Containing Peptides
Authors: Jakobsche Charles E. , Xu Muyun , MacArthur Nicholas S. , Duong Chau Minh , Islam Saadman , McElwee Joseph P.
Published: December 2022

Herein, we detail several specific challenges that hinder the effective synthesis of glutamyl hydrazide containing peptides, and we describe a synthetic strategy to work around these challenges. Glutamyl hydrazide is an unnatural amino acid residue that bears an acyl hydrazide functional group on its side chain. This family of compounds has the potential to provide potent and selective inhibitor molecules for several families of enzymes. During peptide synthesis, however, these side chains—even in protected form—can derail the synthesis by initiating undesired side reactions. Avoiding these side reactions is critical for enabling effective access to this family of compounds.
Enantioselective Synthesis of α-Chiral Amides by Catalytic Hydrogenation with Iridium N,P-Complexes
Authors: Peters Bram B. C. , Birke Norman , Andersson Pher G. , Massaro Luca
Published: December 2022

The catalytic asymmetric hydrogenation of olefins constitutes a powerful method for the preparation of chiral compounds. A series of prochiral unsaturated amides were efficiently reduced with high enantioselectivities by means of an iridium N,P-complex-catalyzed hydrogenation. Its application in the synthesis of fenpropidin and the possibility of using isomeric mixtures of starting materials are attractive features of the method.