bluuebunny/crossref_metadata_2025 huggingface dataset:
KENTSEL DÖNÜŞÜM SÜRECİNDE KENTSEL KİMLİĞİN KORUNMASINA İLİŞKİN BİLİNCİN TWİTTER ÜZERİNDEN DEĞERLENDİRİLMESİ
Authors: Yemen Aysun , Çelik Eda , Çelik Rukiye
Published: October 2018

Avrupa kentlerinin yeniden organize
edilmesi ile birlikte tarih sahnesine çıkan kentsel dönüşüm; kentsel yenileme
pratiklerinin, kentsel kimliğin korunmasının ve bu pratiklerin kentsel dokuya
uyumunun sorgulanmasını beraberinde getirmiştir. Kente özgü kimliğin korunması
mevzusu, sosyal medyanın da etkisiyle kamuoyunda bir duyarlılık oluşturmuştur. Bu
çalışmanın amacı kentsel dönüşüm sürecinde hayata geçirilen pratiklerin kentin
kimliğiyle uyuşup uyuşmadığına ilişkin sosyal medya tartışmalarını
değerlendirmektir. Çalışmada; sosyal medya mecralarından biri olan twitterdaki
kentsel dönüşümle ilgili hashtaglerin altında yer alan tweetler evren olarak
alınmış ve söz konusu evrenden eleştirel söylem analizine dair doyuma ulaşacak
kadar tweet, örneklem olarak seçilmiştir. Çalışmanın amacına hizmet eden tweetler,
örnekleme dâhil edildiği için çalışmanın örneklemi amaçlı örnekleme yoluyla
belirlenmiştir. Örnekleme dâhil edilen tweetler eleştirel söylem analizine tabi
tutulmuştur.
SAĞLIK YÖNETİMİ MEZUNLARININ ÖZ YETERLİLİKLERİNİN İSTİHDAM DURUMUNA ETKİSİ
Authors: Biçer Enis Baha , Ilıman Ebrar , Ekiz Tutku
Published: October 2018

Çalışmanın
amacı: Sağlık Yönetimi Bölümü mezunlarının istihdam durumunu belirlemek ve
öz yeterliliklerinin istihdam durumlarına etkisini saptamaktır. Yöntem: Tanımlayıcı araştırmada elektronik
anket yöntemi kullanılmıştır. Araştırmanın evrenini 1988-2017 yılları
arasındaki Sağlık Yönetimi Bölümü mezunları oluşturmaktadır. Örneklem seçimine
gidilmemiş olunup, örneklemin geçerlilik ve güvenilirliği sağlayacak sayıya
ulaşılması yeterli görülmüştür. Sağlık Yönetimi mezunlarının istihdam durumunu
belirlemeye yönelik olan sorular araştırmanın amacına uygun olarak
araştırmacılar tarafından oluşturulmuştur.
Öz yeterlilik ölçeği olarak Yeşilay (1996)
tarafından hazırlanan ölçek kullanılmıştır. Ölçeğin Cronbach alpha katsayısı
0,920 olarak saptanmıştır. Bulgular:
Çalışmaya 255 kişi katılmış olup, katılımcıların %63.5’i kadın, %36.5’i
erkektir. %41.2’si meslek sahibi iken, %58,8’i çalışmamaktadır. Çalışanların ise
%66.7’si kendi alanında çalışmaktadır. Anketi cevaplayanların öz yeterlilik
düzeyi 3.78±0.89.’dir.
Sonuç: Sağlık Yönetimi
mezunlarının istihdam oranı düşüktür ve meslek sahibi olanların da bir kısmı
kendi alanı dışında çalışmaktadır. Kadınların istihdam düzeyi ise erkeklerden
daha fazladır. Eğitim düzeyi de istihdam oranını büyük ölçüde etkilemektedir.
Araştırmanın bir diğer boyutu olan öz yeterlilik boyutu sonucunda, mezunların
öz yeterliliklerinin yüksek olduğunu görülmüştür. Mezunların cinsiyeti, mezun
oldukları üniversite ve meslek sahibi olma durumları ile öz yeterlilik
düzeyleri arasında anlamlı bir ilişki saptanmıştır. Sonuçlara göre erkeklerin
öz yeterliliklerinin kadınlardan daha yüksek olduğu ve meslek sahibi olanların
öz yeterliliklerinin meslek sahibi olmayanlardan daha yüksek olduğu
görülmüştür.
TÜRKÇE ÖĞRETMEN ADAYLARININ BENİMSEDİKLERİ EĞİTİM FELSEFELERİNİN ÇEŞİTLİ DEĞİŞKENLERE GÖRE DEĞERLENDİRİLMESİ (ZİYA GÖKALP EĞİTİM FAKÜLTESİ ÖRNEĞİ)
Authors: Bingöl Ulaş , Kinay İsmail
Published: October 2018

İnsanı diğer
varlıklardan ayıran en önemli niteliklerinden birisi kendi varlığı hakkında
düşünmesi ve etrafında olup bitenlere anlam verebilmesidir. Kişi kendisi ve dış
dünya ile ilgili düşünmeye başladığı andan itibaren felsefi bir eğilim içine
girer. İnsanoğlunun benimsediği felsefe, çoğu zaman eğitim yolu ile şekillenir.
Bütün mesleklerde olduğu gibi öğretmenlik mesleğinde de benimsenen felsefe
kişinin iş yaşamını bütün boyutları ile etkiler. Öğretmenler benimsedikleri
eğitim felsefesine göre sınıf içerisindeki davranışlarını düzenler; eğitim ve
öğretim ile ilgili karaları alırken benimsedikleri eğitim felsefesinin
tesirinde kalırlar. Bundan ötürü öğretmenlerin benimsedikleri eğitim
felsefelerinin tespiti; eğitim ortamının ve uygulamalarının düzenlenmesine,
ders içeriklerinin belirlenmesine, eğitim programlarının eksikliklerinin
giderilmesine yardımcı olacaktır. Bu çalışmanın genel amacı, Türkçe öğretmen adaylarının benimsedikleri eğitim felsefelerini
çeşitli değişkenler açısından incelemektir. Çalışmanın
katılımcılarını 2016-2017 Yılı Bahar Döneminde Dicle Üniversitesi Ziya Gökalp
Eğitim Fakültesi Türkçe Eğitimi Anabilim Dalında kayıtlı 171 öğretmen adayı
oluşturmaktadır. Bu araştırmada tarama modeli
kullanılmıştır. Veri toplama aracı olarak “Felsefi Tercih Değerlendirme Ölçeği”
kullanılmıştır. Bu araştırmadaki veriler SPSS 20 paket
programı kullanılarak incelenmiştir. Elde edilen bulgular yorumlanarak birtakım
önerilerde bulunulmuştur.
Karyological Studies on Nine Astragalus L. Taxa in Turkey
Authors: GEDİK Osman , KÜRŞAD Murat , KIRAN Yaşar
Published: October 2018

The somatic chromosome number and morphometric properties of nine Astragalus taxa native to Turkey were studied in detail. Somatic chromosome numbers have been determined as follows: A. campylorhynchus Fisch. & C.A.Mey., A. suberosus Banks & Sol., A. densifolius Lam. subsp. densifolius, A. cretaceus Boiss., A. leporinus Boiss. var. hirsutus (Post) Chamberlain, A. anthylloides Lam., A. odoratus Lam. 2n=16, A. lamarckii Boiss. 2n=32, A. camptoceras Bunge, diploid chromosome number 2n = 2x = 16 and 2n = 4x = 32 tetraploid were seen in the cells. Chromosomes of Astragalus taxa, whose karyotype analyses were made, generally had metacentric and sub-metacentric chromosomes. In A. densifolius Lam. subsp. densifolius taxon, one pair satellite chromosomes (sat-chromosome) were observed. Among the species A. leporinus var. hirsutus and A. lamarckii were identified for the first time.
Morbidity profile of paediatric otorhinolaryngological disorders in a rural teaching hospital
Authors: Anwar M. Mohamed , Jesudoss A. , Sowmya P. G. , Thirumalaikolundusubramanian P. , Ismail M.
Published: October 2018

Background: Otorhinolaryngological disorders are more common among children and timely intervention is essential. These disorders variy from one geographical area to another and also differs among different community and age groups. The present study was aimed to assess the different otolorhinolarygological disorders among paediatric age groups.

Methods: This retrospective study was conducted in a rural tertiary care teaching hospital for a period of two years. Data were collected from case sheets and then classified, tabulated and statistically analyzed.  

Results: Among the otorhinolarygological disorders in children, otological, nasopharyngeal and oropharyngeal disorders were 73.67%, rhinological 7.31%, oropharhngeal 5.58% and oral cavity was 4.1% morbidity profile differed among male and female children.

Conclusions: Otologic, nasopharyngeal and its associated disorders reported more among the children in this rural area Variations among gender, age and seasonality were noticed.
Fauna and Larval Habitats Characteristics of Mosquitoes (Diptera: Culicidae) in Golestan Province, Northeast of Iran, 2014–2015
Authors: Sofizadeh Aioub , Reza Shoraka Hamid , Mesgarian Fatemeh , Mohammad Ozbaki Ghorban , Gharaninia Abdolsamad , Sahneh Ebrahim , Dankoob Rohollah , Malaka Ali , Fallah Saeid , Nemani Shamsaddin
Published: October 2018

Background: Mosquitoes (Diptera: Culicidae) is one of the most medically important families of Diptera. The aims of this study were to determine fauna and larval habitat characteristics of mosquitoes in Golestan Province, during 2014–15.
Methods: This study was conducted in larval habitats of mosquitoes and installed ovitraps in 14 districts of Golestan Province, Northern Iran in 2015. Samples were collected with a scoop by ladle handling for entomology. The col­lected larvae were transferred to Laboratory of Medical Entomology in lactophenol solution. Then microscopic slides were prepared using de Faure's formula. Species of each sample was recognized using diagnostic criteria to identify the Culicidae species. Characteristics of larval breeding places were studied based on the habitat type (Permanent or temporary), water conditions (Clear or turbid, stagnant or running), vegetation (out, in, underwater vegetation or without vegetation), sunlight exposure (Full or partial sunlight) and so on. Data were analyzed using SPSS.
Results: Overall, 5661 third- and fourth- instars larvae of mosquitoes were collected and 5 genera and 14 species were identified: Anopheles hyrcanus, An. maculipennis, An. pseudopictus, An. superpictus, Culex hortensis, Cx. mimiticus, Cx. perexiguus, Cx. pipiens, Cx. pusillus, Cx. theileri, Cx. tritaeniohynchus, Culiseta longiareolata, Och­lerotatus caspius, Uranotaenia unguiculata. Culex pipiens was recognized as predominant species of the family. Among the detected species, Cx. pusillus reported for the first time from Golestan Province.
Conclusion: Due to the high species diversity of Culicidae, ecology of medical important species such as Cx. pipiens and Cx. tritaeniorhynchus needs more investigations.
Tick Ectoparasites of Animals in Borderline of Iran-Iraq and Their Role on Disease Transmission
Authors: Banafshi Omid , Ali Hanafi-Bojd Ahmad , Karimi Mohamad , Faghihi Faezeh , Beik-Mohammadi Mojtaba , Gholami Sahere , Javaherizadeh Siavash , Vatandoost Hassan , Telmadarraiy Zakkyeh
Published: October 2018

Background: Since ticks are potent vectors of various diseases, identification of these species are clinically important to protect the public health and control veterinary problems in the communities. We aimed to figure out the frequency of ticks on cows, goats, sheep, lambs, turtles and also obscure hosts in Kurdistan Province, bordered with Iraq June 2012 to May 2013.
Methods: The hosts were selected randomly and examined individually for tick infestation. In case of infestation, ticks were collected using forceps and then preserved in 70% ethyl alcohol. All collected specimens were preserved in tubes and relative information was recorded and then identified based on morphological characteristics.
Results: Totally, 1209 ticks were collected. The prevalence of ticks on cows, sheep, goats, lambs, turtles, poultry and obscure hosts was 11.33%, 55.41%, 6.53%, 5.95%, 0.9%, 8.02% and 11.82% respectively. The mean number of ticks on each animal was 1.6. Number of 5 genera, including Rhipicephalus, Argas, Ornithodoros, Hyalomma and Haem­aphysalis and 9 species; including R. sanguineus (60.05%), R. bursa (0.08), Hy. anatolicum (12.33), Hy. asiaticum (1.49), Hy. aegyptium (0.91), Hy. marginatum (0.08), Haemaphysalis parva (4.22), Hyalomma sp. (0.99), Orni­thodoros lahorensis (11.83), and Argas persicus (8.02) were identified.
Conclusion: The most abundant species in this study area was Rh. sanguineus (60.05%). Due to high prevalence of tick specimens and a variety of collected species from sheep (55.41%), the vaccination of sheep and control of tick vectors are recommended..
PERANAN PENGADILAN AGAMA DALAM PEMBARUAN HUKUM ISLAM DI INDONESIA
Authors: Gunawan Edi
Published: October 2018

Tulisan ini menyoroti mengenai konsep hukum Islam di Indonesia yang telah berkembang dengan berbagai proses sosial yang terjadi, namun tidak mengesampingkan metode-metode yang sangat memperhatikan kepentingan lokal(budaya lokal masyarakat Indonesia). Konsep pembaruan hukum Islam di Indonesia banyak dilakukan melalui hasil ijtihad para hakim dan kajian ilmiah dalam bidang al-ahwal al-Syakhsiyah dan ekonomi Islam. Faktor-faktor penyebab terjadinya pembaruan hukum, antara lain: adanya perubahan kondisi, situasi, tempat, dan waktu,untuk mengisi kekosongan hukum karena norma-norma yang terdapat dalam kitab-kitab fikih tidak mengaturnya, sedangkan kebutuhan masyarakat terhadap hukum masalah baru sangat mendesak untuk diterapkan, pengaruh globalisasi ekonomi dan IPTEK,
Akibat Hukum Cacat Kehendak terkait Hakikat Benda pada Perjanjian Jual Beli Batu Akik Bongkahan
Authors: Akbar Ilham
Published: October 2018

Perjanjian jual beli batu akik bongkahan adalah suatu perjanjian, dimana pihak yang satu mengikatkan dirinya untuk menyerahkan batu akik bongkahan dan pihak yang lain untuk membayar harga yang telah dijanjikan. Jual beli dianggap telah terjadi diantara kedua belah pihak, seketika setelahnya orang-orang tersebut mencapai kata sepakat tentang batu akik bongkahan tersebut dan harganya, meskipun batu akik bongkahan itu belum diserahkan, maupun harganya belum dibayar. Syarat sahnya sebuah perjanjian ada 4 (empat), yaitu : (1) sepakat, (2) cakap, (3) objek tertentu dan (4) kausa yang tidak dilarang. Tidak terpenuhinya syarat pertama dan kedua akibat hukumnya perjanjian dapat dapat dibatalkan dan tidak terpenuhinya syarat ketiga dan keempat akibat hukumnya batal demi hukum. Cacat kehendak dalam perjanjian batu akik bongkahan terjadi ketika terjadi ketidaksesuaian kehendak para pihak pihak karena adanya kesesatan dan/atau penipuan. Hakikat benda batu akik bongkahan terdiri atas jenis, kualitas dan/atau daerah asalnya. Akibat hukum adanya cacat kehendak ini yaitu : a). perjanjian batal ketika kesepatakan belum tercapai diantara para pihak; b). perjanjian dimohonkan gugatan pembatalan kepada pengadilan ketika kesepakatan sudah tercapai; atau c) perjanjian dimohonkan gugatan pembatalan karena penipuan beserta gugatan ganti rugi ketika kesepakatan yang sudah tercapai terdapat kesengajaan dari salah satu pihak untuk mempengaruhi keputusan pihak lainnya dengan cara melanggar hukum.
PERGESERAN ORIENTASI PENELITIAN HUKUM: DARI DOKTRINAL KE SOSIO-LEGAL
Authors: Hakim Muhammad Helmy
Published: October 2018

Penelitian hukum doktrinal dalam pendidikan tinggi akan lebih diperkaya jika menyediakan sedikit ruang bagi penelitian hukum sosio-legal yang bersifat interdisipliner. Pendekatan ini akan membantu menemukan dan menjelaskan keterkaitan hukum dan masyarakat. Dengan demikian diharapkan akan lahir para sarjana profesional yang tidak hanya paham tentang ilmu hukum, tetapi juga insan hukum yang dapat berfungsi maksimal karena paham tentang sendi-sendi keadilan masyarakatnya sendiri. Oleh karenanya dibutuhkan suatu pendekatan hukum yang bisa menjelaskan hubungan antara hukum dan masyarakat, maka pendekatan socio-legal merupakan salah satu alternatifnya
Wakaf Tunai sebagai Instrument dalam Peningkatan Ekonomi Umat
Authors: Kadir Abdul
Published: October 2018

Dalam sejarah Islam, wakaf telah memainkan peran yang sangat signifikan dalam meningkatkan kesejahteraan kaum muslimin, baik di bidang pendidikan, pelayanan kesehatan, pelayanan sosial dan kepentingan umum, keagamaan, pengembangan ilmu pengetahuan dan peradaban Islam secara umum. Salah satu bentuk wakaf yang berkembang di zaman klasik Islam bahkan sampai zaman modern ini adalah wakaf tunai. Untuk mengoptimalisasi wakaf tunai, maka tulisan ini akan difokuskan pada dua aspek besar yaitu pembangunan yang bersifat fisik dan pemberdayaan dan pengembangan. Penyaluran dana hasil wakaf itu bisa untuk: 1). Dalam bidang pendidikan, 2). Dalam bidang kesehatan dan fasilitas Rumah Sakit, 3). Dalam bidang pelayanan sosial, 4). Dalam bidang pengembangan usaha kecil dan menengah (UKM)
Hyponatremia among Psychiatric Patients Using Antipsychotic Medication in a Tertiary Hospital in South-South, Nigeria
Authors: Olose Emmanuel O. , Chukwujekwu Donald C. , Igwe Monday N. , Aguocha Miriam C. , Busari Cecilia O. , Opara Sidney K. ,   Department of Psychiatry, University of Calabar, Cross River State, Nigeria.,   Department of Psychiatry, University of Port Harcourt, Port Harcourt, Nigeria.,   Department of Psychological Medicine, Ebonyi State University, Abakaliki, Nigeria.,   Department of Internal Medicine, Imo State University Teaching Hospital, Orlu, Nigeria.,   Department of Clinical Services, Federal Neuropsychiatric Hospital, Calabar, Nigeria.,   Department of Internal Medicine, University of Calabar, Cross River State, Nigeria.
Published: October 2018

The aim of this study was to determine the prevalence of hyponatremia among psychiatric patients taking antipsychotics, to determine the correlation between serum sodium levels and dosage of medications as well as to determine the association between class of antipsychotic medication and serum sodium levels among patients taking antipsychotic medications. This is a longitudinal study. From 92 consenting antipsychotic na�ve patients who met the inclusion criteria, sociodermographic interview schedule was administered. Thereafter, a single venous blood sample was obtained for serum electrolyte analysis and repeated after 6 weeks. Prevalence of hyponatremia was 19.4%, there was a correlation between hyponatremia and dose of antipsychotic in chlorpromazine equivalent (r = −0.354; p = 0.01), and there is an association between typical antipsychotic use and hyponatremia. The use of both typical and atypical antipsychotic medications can lead to hyponatremia. This is in keeping with previous reports.
Safety of Breastfeeding by Mothers on Immunosuppressive Medication for Renal Transplantation: Obsession, Myth and Truth
Authors: Sharma Ajay
Published: October 2018

It is very natural to be concerned that immunosuppressive medications might be deemed hazardous to infant's breastfed by mothers who are transplanted. This is due to lack of good quality guidelines supported by robust evidence. The drugs that are not safe during pregnancy are not necessarily unsafe during breastfeeding. On reviewing non-transplant patients, we noted that there was no adverse effect reported in infants who were breastfed by mothers receiving steroids even in a high dose of prednisolone 50mg/day. Azathioprine levels were undetectable in breast milk or in infant blood and were not associated with increased risk of infection on a long-term follow-up. Cyclosporine levels are undetectable or at insignificant levels in infants breastfed by mothers on this drug. Tacrolimus levels were detected in infants' serum but at insignificantly low levels. In regards to mycophenolate mofetil and belatacept, the data based on animal studies is rather limited. There is still no conclusive evidence regarding the safety of motor inhibitors during breastfeeding. In conclusion, it is safe for mothers to breastfeed while on immune suppression that includes steroids, cyclosporine, tacrolimus or azathioprine. Nonetheless, a close follow-up of these infants is of paramount importance
Horozibiği (Amaranthus mantegazzianus)’nde Farklı Azot ve Fosfor Seviyelerinin Ot Verimi ve Bazı Silaj Özelliklerine Etkisi
Authors: DUMANOĞLU Zeynep , GEREN Hakan
Published: October 2018

Horozibiği bitkisinde farklı azot ve fosfor seviyelerinin verimliliğe olan etkisini değerlendirmek için “Don Juan” isimli horozibiği genotipinde, beş azot (0, 5, 10, 15, 20 kg/da) ve üç fosfor (0, 5, 10 kg/da) seviyesinden oluşan bir saksı denemesi dış ortamda yürütülmüştür. Çalışmada, bitki boyu, yaprak sayısı, doğal kuru madde oranı, yaş ot ve kuru madde verimi, silaj pH’sı, silaj ham protein oranı, NDF ve ADF oranları incelenmiştir. Sonuçlara göre, artan azot ve fosfor seviyelerinin kontrol uygulamasına verim ve verim unsurlarına olumlu yönde etki ettiği, en yüksek KM verimi ve kabul edilebilir silaj yemi özellikleri N15 ile P10 uygulamasından elde edilmiştir.
Analyzing Abnormal Return Before And After The Announcement Of Merger And Acquisition In 2018
Authors: Haryanto Sonny , Mardiyati Umi , Buchdadi Agung Dharmawan
Published: October 2018

This study aims to analyze the abnormal returns before and after the announcement of mergers and acquisitions in the companies listed on the IDX 2018. In this study the observation period taken was three days before and after the announcement of mergers and acquisitions with the number of samples observed were 9 companies. The method for calculating abnormal returns used is the market adjusted return by using an intraday stock price of 15 minutes. Based on testing hypotheses conducted by paired sample t-test, it was found that there were no significant differences in abnormal returns before and after the announcement of mergers and acquisitions in each 15 minute period.
Efficient numerical simulations with Tensor Networks: Tensor Network Python (TeNPy)
Authors: Hauschild Johannes , Pollmann Frank
Published: October 2018

Tensor product state (TPS) based methods are powerful tools to
efficiently simulate quantum many-body systems in and out of
equilibrium. In particular, the one-dimensional matrix-product (MPS)
formalism is by now an established tool in condensed matter theory and
quantum chemistry. In these lecture notes, we combine a compact review
of basic TPS concepts with the introduction of a versatile tensor
library for Python (TeNPy) [1]. As concrete examples, we consider the MPS based
time-evolving block decimation and the density matrix renormalization
group algorithm. Moreover, we provide a practical guide on how to
implement abelian symmetries (e.g., a particle number conservation) to
accelerate tensor operations.
Comparison of Mini-Laparoscopic and Conventional Laparoscopic Surgery for Tubal Ligation
Authors: Gencdal Servet , Ekmekci Emre
Published: October 2018

Objective: To compare the intraoperative characteristics and postoperative results of mini laparoscopic and conventional laparoscopic surgeries performed for surgical sterilization.Study Design: This retrospective study was conducted to compare the conventional and mini laparoscopic tubal ligation for surgical tubal sterilization. In total of 39 women, 22 in the conventional laparoscopy and 17 in the mini laparoscopic surgery group participated in the study. The main outcome measures were total operation time, amount of bleeding, intraoperative complications, skin scar formation with patient scale and observer scale and length of hospital stay. Results: Demographical findings did not differ between the two groups. Similarly, rates of intraoperative complications, conversion to laparotomy, length of hospital stay, pre and postoperative hematocrit levels were not significantly different between the groups. Both patient and observer POSAS scores were better in mini laparoscopic surgery group. Conclusion: Mini laparoscopic surgery seems a safe and feasible alternative to conventional laparoscopy for surgical tubal sterilization.
Metabolomics of Exhaled Breath Condensate by Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry: A Methodological Approach
Authors: Maniscalco Mauro , Cutignano Adele , Paris Debora , Melck Dominique J. , Molino Antonio , Fuschillo Salvatore , Motta Andrea
Published: October 2018

:

Respiratory diseases present a very high prevalence in the general population, with an
increase in morbidity, mortality and health-care expenses worldwide. They are complex and heterogeneous
pathologies that may present different pathological facets in different subjects, often
with personal evolution. Therefore, there is a need to identify patients with similar characteristics,
prognosis or treatment, defining the so-called phenotype, but also to mark specific differences
within each phenotype, defining the endotypes.

:

Biomarkers are very useful to study respiratory phenotypes and endotypes. Metabolomics, one of
the recently introduced “omics”, is becoming a leading technique for biomarker discovery. For the
airways, metabolomics appears to be well suited as the respiratory tract offers a natural matrix, the
Exhaled Breath Condensate (EBC), in which several biomarkers can be measured. In this review,
we will discuss the main methodological issues related to the application of Nuclear Magnetic
Resonance (NMR) spectroscopy and Mass Spectrometry (MS) to EBC metabolomics for investigating
respiratory diseases.
Phenolic Imidazole Derivatives with Dual Antioxidant/Antifungal Activity: Synthesis and Structure-Activity Relationship
Authors: Bettencourt Ana P. , Castro Marián , Silva João P. , Fernandes Francisco , Coutinho Olga P. , Sousa Maria J. , Proença Maria Fernanda , Areias Filipe M.
Published: October 2018

Background:

Previous publications show that the addition of a phenolic antioxidant to
an antifungal agent, considerably enhances the antifungal activity.

Objective:

Synthesis of novel compounds combining phenolic units with linear or cyclic nitrogencontaining
organic molecules with antioxidant/antifungal activity using methodologies previously
developed in the group.

Methods:

Several N- [1,2-dicyano-2- (arylidenamino) vinyl]-O-alkylformamidoximes 3 were synthesized
and cyclized to 4,5-dicyano-N- (N´-alcoxyformimidoyl)-2-arylimidazoles 4 upon reflux in
DMF, in the presence of manganese dioxide or to 6-cyano-8-arylpurines 5 when the reagent was
refluxed in acetonitrile with an excess of triethylamine. These compounds were tested for their antioxidant
activity by cyclic voltammetry, DPPH radical (DPPH•) assay and deoxyribose degradation
assay. The minimum inhibitory concentration (MIC) of all compounds was evaluated against
two yeast species, Saccharomyces cerevisiae and Candida albicans, and against bacteria Bacillus
subtilis (Gram-positive) and Escherichia coli (Gram negative). Their cytotoxicity was evaluated in
fibroblasts.

Results:

Among the synthetised compounds, five presented higher antioxidant activity than reference
antioxidant Trolox and from these compounds, four presented antifungal activity without
toxic effects in fibroblasts and bacteria.

Conclusion:

Four novel compounds presented dual antioxidant/antifungal activity at concentrations
that are not toxic to bacteria and fibroblasts. The active molecules can be used as an inspiration
for further studies in this area.
Modeling an Airlift Reactor for the Growing of Microalgae
Authors: Lara Gustavo A. , Moreno Luis , Ramírez Yendery , Cisternas Luis A.
Published: October 2018

Objective:

The flow dynamics of an airlift reactor for the growing of microalgae is modeled using Computational Fluid Dynamics (CFD). The model is applied to the operation and optimization of the reactor, giving a valuable picture of the liquid movement and carbon dioxide trajectory at different air injection flow rates.

Methods:

A novel aspect of the model is that air and carbon dioxide are injected at separated locations. Air is injected at the bottom of the reactor and CO2 injection takes place in the downcomer region of the reactor to obtain longer CO2 paths, improving its transference.

Results:

The results show modeling is a useful tool in the control of the reactor operation; for example, in avoiding the sedimentation of microalgae or for detecting the existence of zones with extremely low CO2 concentrations.
O poema sobre o poema. A poesia em construção do barroco ao contemporâneo
Authors: Barros Anabela Real de
Published: October 2018

Reporta-se este trabalho à autorreflexividade poética, centrando-se nos textos em processo ou em construção, em particular no soneto, e sobretudo no período barroco e no Siglo de Oro castelhano, através da recolha e edição de vários poemas inéditos. A sua fortuna e atualidade ficam bem patentes no cultivo que ao longo dos séculos, e até aos nossos dias, se tem feito desse estilo e subgénero.
NOTA DE APRESENTAÇÃO
Authors: Sousa Sérgio
Published: October 2018

Em perfeita consonância com o que sucede noutras áreas do conhecimento, em que ao papel da emoção é dada uma relevância considerável, senão mesmo fundamental, o número 31.2 da revista Diacrítica é tematicamente dedicado ao estudo das emoções na ficção literária e na criação cultural. Neste sentido, reúne ensaios que de um modo interdisciplinar abordam, sob o ângulo emocional, um conjunto diverso de conteúdos e representa-ções literário-culturais.Afora esta secção temática, na primeira parte da revista (Vária),o leitor encontra estudos consagrados a outras problemáticas. A partir deste número 31.2, a revista Diacrítica inicia um novo formato. A anterior organização em três números anuais correspondentes às linhas de investigação em Linguística, Literatura e Filosofia & Cultura, será subs-tituída por números temáticos que abordarão questões atuais de investiga-ção nos diversos campos da atuação do CEHUM, mantendo a revista a sua periodicidade trimestral.
Motivation, Fortitude and Success: The Impact of Academic Efficacy and Academic Commitment on Academic Performance among Minority High School Students
Authors: Hughes Christina , Jones-Adams Carla , Branham Sr. David
Published: October 2018

The importance of understanding the elements of success in the education of minority high school students is immense. Recognizing the causes of academic success for these students allows educators to employ better educational and motivational strategies. It has been shown that academic efficacy and academic commitment have a positive impact on academic performance. However, the interaction and relationship between these two variables in having a positive effect on education outcomes among minority high school students is not clear. This paper looks at the relationship between academic efficacy and academic commitment on academic performance among minority high school students. The findings reveal that academic commitment is positively associated with academic performance. However, while academic efficacy has a positive impact on academic commitment the results show that academic efficacy has no direct impact on academic performance among the respondents.
EXPERIMENTAL FORCED SOLAR THIN LAYER GINGER DRYING
Authors: Kumar Mahesh
Published: October 2018

In this research paper, the convective and the evaporative heat transfer coefficients of ginger (zingiber officinale) drying in an indirect solar cabinet dryer under the induced forced convection mode is presented. Experiments were conducted during the month of March 2015 under the climatic conditions of Hisar, India (29°5’5”N latitude and 75°45’55”E longitude). The experimental data obtained for solar drying of a constant ginger mass of 150 g has been used to determine constants ‘C’ and ‘n’ in the Nusselt number expression using linear regression analysis; consequently, the convective and the evaporative heat transfer coefficients have been evaluated. The average value of constants ‘C’ and ‘n’ were evaluated as 0.999 and 0.318, respectively. The average values of the convective and the evaporative heat transfer coefficients were found to be 3.95 W/m2 °C and 160.47 W/m2 °C, respectively, for the given mass samples of ginger. The average collector efficiency was observed to be 14.5%. The experimental error in terms of percentage uncertainty was found to be 20.87%.
REDUCTION OF RESIDUAL SHEAR STRESS IN THE LOADED CONTACT USING FRICTION HYSTERESIS
Authors: Kraft Adrian , Pohrt Roman
Published: October 2018

We investigate the tangential contact problem of a spherical indenter at constant normal force. When the indenter is subjected to tangential movement, frictional shear stresses arise at the interface and do not vanish when it is moved backwards. We study the evolution of shear stress when the indenter is moved back and forth at falling amplitude. The method of dimensionality reduction (MDR) is employed for obtaining the distribution of stick and slip zones as well as external forces and the final stress distribution. We find that the shear stress decreases. For the special case of linearly falling amplitude of the movement, we observe uniform peaks in the shear stress. The absolute value of the shear stress peaks is reduced best for a high number of back-and-forth-movements with slowly decreasing amplitude.
SPLITTING THE TOTAL EXERGY DESTRUCTION INTO THE ENDOGENOUS AND EXOGENOUS PARTS OF THE THERMAL PROCESSES IN A REAL INDUSTRIAL PLANT
Authors: Vučković Goran , Vukić Mića , Stojiljković Mirko , Simonović Miloš
Published: October 2018

The total exergy destruction occurring in a component is not only due to the component itself (endogenous exergy destruction) but is also caused by the inefficiencies of the remaining system components (exogenous exergy destruction). Hence care must be taken in using the total exergy destruction of a component for making decisions to optimize the overall energy system. In this paper, a complex industrial plant is analyzed by splitting the component’s exergy destruction into its endogenous part (the part resulting totally from the component’s irreversibilities) and its exogenous part (resulting from the irreversibilities of the other components within the system). It is observed that the steam generator has the dominant effect. From the total exergy destruction in the steam generator, 1,097.63 kW or 96.95% come from internal irreversibilities in the component, while the influence of other components on the loss of useful work in the steam generator is only 3.05%.
On the challenge of five-hole-probe measurements at high subsonic Mach numbers in the wake of transonic turbine cascades
Authors: Boerner Marcel , Bitter Martin , Niehuis Reinhard
Published: October 2018

Five-hole-probes are common use in turbomachinery flow investigations, even though, inserting a probe into a flow field inevitably induces perturbations to the flow which can falsify the measurement results, especially when exposed to transonic flows. The objective of the investigations presented here is to evaluate the Mach number measurements of a five-hole-probe (5HP) in the wake flow of a transonic turbine cascade at engine relevant Reynolds numbers by comparing them to the results of particle image velocimetry (PIV). Furthermore, PIV measurements were performed with inserted probe to investigate the influence of the probe on the wake flow field. Together with a sensitivity study of 5HP measurements in flow regimes close to Ma = 1, the results demonstrate how the measurement uncertainty can be improved in high subsonic flow regimes.
235 YEARS ON THE GUARD OF HEALTH OF SEAS OF THE BLACK SEA FLEET
Authors: Murynin V. A. , Zubarev A. A.
Published: October 2018

June 16, 2018 year marks anniversary 235 Rams 1472 VMKG Russian Defense Ministry hospital is Today. Multidisciplinary specialized military medical institution, standing at the forefront of modern medicine. Being coeval of the city of Sevastopol and the Black Sea fleet hospital in 235 anniversary rightfully takes its dignified and Honorable place. With 2016 year experts of the hospital, the first in the southern military region among military medical organizations, began to provide high-tech medical care. The hospital is a major methodological centre of medical service The Black Sea fleet and the Southern military district, with rich experience of practical work in the context of war and peace.
MULTI-LEVEL DAMAGE OF PERIPHERAL NERVOUS SYSTEM IN CLINICAL PRACTICE OF NAVAL AND MILITARY MEDICINE
Authors: Litvinenko I. V. , Zhivolupov S. A. , Bulatov A. R. , Kuzina E. E. , Provotorov E. A.
Published: October 2018

Damage to the peripheral nerves and spinal roots in natural anatomical tunnels is not only a common form of damage to the nervous system, but also an important medical and social problem; because tunnel neuropathy and degenerative-dystrophic diseases of the spine are one of the most common reasons for the release of citizens from the call, the dismissal of military personnel from the Armed Forces of the Russian Federation, seafarers, changes in the category of fitness for military service. According to various authors, the combination of compression — ischemic neuropathies with signs of spinal cord lesions occurs in 30–70% of cases of tunnel syndromes. This is especially true for seafarers, because they are more likely to be affected by the musculoskeletal system, as long-term, monotonous load can lead to micro-traumatization and micro-hemorrhage, followed by scarring of muscles, tendons, ligaments, fascia and, as a consequence, the narrowing of natural anatomical tunnels. Revealed the existence of a relationship between the sea and the frequency of lesions of the spine, the shoulder girdle, with the emergence of the syndrome of the rotator cuff and carpal tunnel syndrome. In military personnel, this may occur during excessively long compression of the upper arms during shooting, training, work in low temperatures and vibration.
THE DYNAMICS OF INDICATORS OF THE COMPONENT COMPOSITION OF THE ORGANISM OF SEAMS IN A LONG-AWAY SEA TRACK
Authors: Andriyanov A. I. , Polyakov V. I. , Tshukina N. A. , Subbotina T. I. , Konovalova I. A. , Smetanin A. L. , Korosteleva O. G.
Published: October 2018

The dynamics of indicators of the component composition of the seamen’s organism of the surface ship of the Navy in the conditions of a long march in interaction with the crew’s feeding habits is considered in the article. The actual nutrition of the surveyed persons was estimated using the calculation method based on the analysis of the chemical composition and energy value of the products of the daily diet, taking into account the culinary losses described in the handbook on the chemical composition and caloric content of Russian foodstuffs edited by V. A. Tutelyan. Standard data on incomplete digestibility by a person of various classes of nutrients are taken into account. In the organization of the actual power supply of the crew there were shortcomings associated with a decrease in the energy value of the ration, an imbalance of mineral and vitamin compounds, due to the actual assortment of products obtained for marching at the rate of sea rations. Estimated content of vitamins (-carotene, thiamine, riboflavin, niacin and ascorbic acid) and mineral substances (potassium, phosphorus, magnesium, iron) in the daily diet throughout the long maritime expedition was significantly lower than those regulated by medical and technical requirements the norm of sea rations. Changes that have a nonrandom character occurred according to the indices of abdominal fat: waist circumference and waist-hip index. By the end of the campaign, 71% of the surveyed had a tendency to increase their body weight. At the same time, the body weight increased due to both subcutaneous and abdominal fat, which was reflected in the increase in visceral fat, body fat and body mass index. The data obtained in the course of the work confirm that the existing ration does not need to increase its energy content, but requires improvement in quality composition. Based on the data obtained, it is proposed to increase the protein content in the diet with the reduction of fats and simple carbohydrates using rational substitutions; increase the proportion of fresh fruits and vegetables to improve digestion.
TOXICOLOGY OF GASEOUS ENVIRONMENT IN DECOMPRESSION CHAMBER
Authors: Sokolov G. M. , Suvorov A. V. , Logunov A. T.
Published: October 2018

The paper presents basic concepts of toxicological problems under human containment in a closed hermetic hyperbaric volume basing on the literature data and our own long-term scientific and practical experience aimed at diving and diving medicine, development and testing of the decompression chambers. The paper describes the following essentials of the problem: gaseous atmospheric composition in closed hermetic volumes, evolution of exogenous gases in human organism under lowering in the chamber, evolving hazardous gaseous substances (HGS) in the closed volume, design average daily rate of HGS evolving, effect of conditions on HGS evolving, their maximum permissible concentrations, methods of СО2 and HGS removal in the chambers, and regulatory requirements. It is shown that the most of the modern existing chambers do not meet the regulatory requirements that may result in negative effects on human health. The ways to except the cases of human intoxication in the decompression chambers and systems are offered in the paper.
KEY PERSONNEL OF SURGERY DEPARTMENT OF KRONSTADT HOSPITAL DURING THE GREAT PATRIOTIC WAR
Authors: Chechko A. N.
Published: October 2018

Human history knows no other such tough time but that fell to the lot of Soviet people during the Great Patriotic War. But also it doesn’t know such common heroism, courage and win to victory that Soviet people showed fighting in fields and behind enemy lines every day. It stands to mention selfless work of military medicine. Surgeons and organizers of medical service for wounded were the most essential people that time. Collective of 35-th Kronstadt Naval Hospital that worked on island Cotlin was also in difficult conditions. There was no communication with scientific and educational health care institutions, therefore military medicine had to work in severe conditions of blockade. Surgeon service of Kronstadt Naval Hospital performed a mission properly. Dozens of thousands wounded and sick were kept going and their health recovered. This article is devoted to scientific, clinical and organizational activities of heads of surgery departments of Kronstadt Naval Hospital who worked during the war. Their contribution to the development of native military medicine is shown in the article.
Needs Analysis in Role Playing Learning Model Influence on Motivation and Biology Learning Outcome of the Students at SMA Negeri 3 Samarinda
Authors: Rosifah Djumroh , Masruhim Muh Amir , Sukartiningsih Sukartiningsih
Published: October 2018

This study addresses four domains: 1) description of Role Playing learning model use as a learning strategy in Biology instructional process at school, 2) perspectives and threats obtained by teachers at school when addressing Protein Synthesis topic 3) Role Playing learning model in Protein Synthesis topic of Biology learning, 4) the influence of Role Playing learning model towards motivation and Biology learning outcome. The results of this study is teacher needs analysis instruments, analysed using descriptive qualitative. The study showes that the use of Role Playing Instructional Model during Biology learning process has not been performed at school according to three reasons: 1) obstacles obtained when addressing the topic which is difficult to observe, 2) the difficulties obtained when addressing Protein Synthesis topic, in this case, teacher needs to apply Role Playing instructional Model to engage students with their environment, 3) Role Playing as an instructional model that demands students to learn from their experience in order to motivate and improve their learning outcomes.
Teacher Problem Analysis in the Development of Biology Learning Tools Integrated by Reading Questionning and Answering (RQA) Learning Model in Senior Highschool
Authors: Winarno Winarno , Tindangen Makrina , Palenewen Evie
Published: October 2018

This study adressed three aspects: (1) how Senior Highshool Biology teachers perceive about learning tools (2) how the skills of Senior Highshool Biology teachers in managing learning tools (3) what are problems obtained by teachers according to planning and implementation of learning tools with the integration of Reading, Qusetioning and Answering (RQA). This study is the prerequisite study to analyse the needs for the development of learning tools integrated by Reading, Questioning and Answering (RQA) in Senior Highschool. Method used in this study is qualitative descriptive. The conculion obtained from this study includes: (1) the lack of expertise about learning tools in Senior Highschool Biology teachers, (2) the lack of ability in them to manage learning tools, (3) problems obtained in them related to the planning and implementation of the learning tools integrated by Reading, Qusetioning and Answering (RQA) learning model.
GAMBARAN ASUPAN CAIRAN DAN STATUS GIZI PADA MAHASISWA KEDOKTERAN UNIVERSITAS JAMBI
Authors: Halim Rita , Hana Marisa , Mardhiyah Mardhiyah
Published: October 2018

ABSTRACT

 

Background: Fluids are one of the essential nutritional elements in the body. The Indonesian Regional Dehydration Study (THIRST) finds that 46.1% of Indonesians are mildly dehydrated and the number is higher in adolescents at 49.5%. The RISKESDAS report in 2013 states that some teenage groups in Indonesia are also experiencing overweight and the number continues to increase every year. This study aims to determine the fluid intake and nutritional status in medical students of Jambi University in 2017.

 

Method: This research is a descriptive research with cross-sectional approach conducted in August-September 2017. The number of samples was 90 people. Data of fluid intake was obtained from the filling of 3x24 hour fluid diary and nutritional status based on Body Mass Index (BMI).

 

Results: The results show the average fluid intake of the study subjects was 2100 ml / day, but  74.4% are categorized as insufficient fluid intake. The average nutritional status of research subjects based on BMI was 22.36 kg / m2, with the normal nutritional status was 45.6%, above normal was 40%, and below normal was 14.4%.

 

Conclusions: Most of the study subjects were included in the category of insufficient fluid intake and overweight occurred more in women.

 

Keywords: Fluid intake, Nutrition Status, Medical Student

 

ABSTRAK

 

Latar Belakang : Cairan merupakan salah satu unsur gizi esensial dalam tubuh. Hasil penelitian The Indonesian Regional Dehydration Study (THIRST) menyebutkan bahwa 46,1% penduduk Indonesia mengalami dehidrasi ringan dan jumlah tersebut lebih tinggi pada remaja yaitu 49,5%. Laporan RISKESDAS tahun 2013 menyebutkan bahwa sebagian kelompok remaja di Indonesia juga mengalami gizi lebih dan angka tersebut terus mengalami peningkatan setiap tahun. Penelitian ini bertujuan untuk mengetahui Gambaran Asupan Cairan dan Status Gizi Pada Mahasiswa Kedokteran Universitas Jambi Tahun 2017.

Metode : Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional yang dilakukan pada Agustus-September 2017. Jumlah sampel sebanyak 90 orang. Data asupan cairan diperoleh dari pengisian fluid diary 3x24 jam dan status gizi berdasarkan indeks massa tubuh (IMT).

 

Hasil : Hasil penelitian menunjukkan rerata asupan cairan subjek penelitian yaitu 2100 ml/hari, akan tetapi sebagian besar termasuk dalam kategori asupan cairan kurang yaitu sebanyak 74,4%. Sedangkan status gizi subjek penelitian berdasarkan IMT didapatkan rerata 22,36 kg/m2 dengan status gizi normal sebesar 45,6%, status gizi lebih sebesar 40%, dan status gizi kurang sebesar 14,4%.

 

Kesimpulan : Sebagian besar subjek penelitian termasuk dalam kategori asupan cairan kurang dan status gizi lebih lebih bayak terjadi pada perempuan .  

 

Kata kunci : Asupan Cairan, Status Gizi, Mahasiswa Kedokteran
Colangiocarcinoma en pacientes con colangitis esclerosante primaria
Authors: Guerrero Bermudez Camila Andrea , Vélez Marín Mariana , Restrepo Gutiérrez Juan Carlos
Published: October 2018

La colangitis esclerosante primaria (CEP) es una enfermedad inflamatoria poco común que afecta los conductos biliares produciendo colestasis. Actualmente el único tratamiento disponible es el manejo sintomático con ácido ursodesoxicólico y el trasplante hepático. Además de ser una etiología de cirrosis a largo plazo, en su historia natural tiene una asociación importante con el colangiocarcinoma (CCA), una neoplasia agresiva que es casi exclusiva de este grupo de pacientes y hoy día constituye su principal causa de muerte, debido a que es de difícil diagnóstico y cuenta con opciones muy limitadas de tratamiento.En el presente artículo se exponen conceptos actuales sobre esta patología enfatizando en la importancia de realizar una adecuada tamización con pruebas diagnósticas efectivas (CA 19-9 y colangioresonancia) que ayuden a diferenciar el CCA de procesos benignos para detectarlo en estadios tempranos donde la probabilidad de tratamiento curativo es mucho mayor.