bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Impact of Engineering Measures and Vegetation Restoration on Soil Erosion: A Case Study in Osmancık, Türkiye
Authors: Ediş Semih , Timur Özgür Burhan , Tuttu Gamze , Aytaş İbrahim , Göl Ceyhun , Özcan Ali Uğur
Published: August 2023

The prioritization of preventing soil loss in Türkiye’s watersheds has become a pressing concern for planners. Numerous mathematical models are presently utilized on a global scale for soil erosion prediction. One such model is the Revised Universal Soil Loss Equation (RUSLE), commonly used to estimate average soil loss. Recently, there has been an increased emphasis on utilizing USLE/RUSLE in conjunction with Geographic Information System (GIS) technology, enabling grid-based analysis for predicting soil erosion and facilitating control measures. This study evaluates the effectiveness of erosion and flood control initiatives started in the 1970s within the Emine Creek watershed and its tributary rivers in Osmancık, Türkiye, utilizing RUSLE/GIS technologies. Two distinct maps illustrating the potential erosion risks were produced for two distinct temporal intervals, and a comparative analysis was conducted to evaluate the alterations that transpired. The implementation of various measures such as terracing, afforestation, and rehabilitation in the watershed led to a notable prediction of decreasing soil loss in the watershed. From 1970 to 2020, the rate of estimated soil loss was reduced from 417 to 256 metric tons per hectare per year, demonstrating the effectiveness of soil conservation measures in a semi-arid and weakly vegetated area at reducing potential soil loss.
Research on Design and Optimization of Large Metal Bipolar Plate Sealing for Proton Exchange Membrane Fuel Cells
Authors: Zhao Jinghui , Guo Huijin , Ping Shaobo , Guo Zimeng , Lin Weikang , Yang Yanbo , Shi Wen , Wang Zixi , Ma Tiancai
Published: August 2023

The sealing system, as the most important load-bearing component, is a critical part of the stack assembly in a proton exchange membrane fuel cell (PEMFC). Currently, flat or single-peak sealing gaskets are commonly used for large metal bipolar plate sealing, which can easily cause problems such as significant internal stress and distortion displacement. In order to solve this problem, an innovative double-peak sealing gasket structure is proposed. Based on the Mooney–Rivlin constitutive model, the impact of the sealing material hardness, friction coefficient, and compression ratio on the sealing performance are investigated. Meanwhile, the double-peak seal is fabricated and assembled into a single fuel cell for testing. The results show that the sealing performance of a double-peak sealing gasket with extended wings has been optimized, and the maximum contact pressure on the upper and lower contact surfaces is 1.2 MPa and 0.67 MPa, respectively, which is greater than the given air pressure of 0.1 MPa. And the sealing effect is optimal with a 45 Shore A hardness rubber, a friction coefficient of 0.05, and an initial compression ratio of 35%. The simulation and experimental sealing performance of the sealing gasket under different compression ratios remain similar.
Gender Mainstreaming in Miraa Farming in the Eastern Highlands of Kenya
Authors: Ndubi Jessica , Murithi Festus , Thuranira Elias , Murage Alice , Kathurima Cecilia , Gichuru Elijah
Published: August 2023

Miraa (Catha edulis forsk) farming is a major income earner in Kenya, but until recently, it was not scheduled as a priority crop in the country. Consequently, no gender research to identify men and women issues with the purpose of designing gender-responsive solutions for increased productivity has ever been conducted on the crop value chain. The main objective of the study was to examine gender issues in miraa production and marketing activities in Kenya. Data were collected using multiple methods. These included a formal survey that covered 962 households, key informants’ interviews, focused group discussions and a literature review. The household data were analyzed through descriptive statistics using SPSS Version 20 software. The Harvard theoretical framework was used to structure the analysis. The main findings indicate that women have less access to production resources such as land and extension services than men. Moreover, men performed almost all crop activities. Men also dominated all crop decisions. The study recommends that research scientists need to design gender-responsive technologies, innovations and management practices that are tailor made to meet men’s needs and concerns. This is because the crop appears to belong to men with less women’s operational and financial control.
Multi-Sensor Information Fusion and Multi-Model Fusion-Based Remaining Useful Life Prediction of Fan Slewing Bearings with the Nonlinear Wiener Process
Authors: Liu Mingjun , Dong Zengshou , Shi Hui
Published: August 2023

Many factors affect the accuracy of the estimation of the remaining useful life (RUL) of the fan slewing bearings, thereby limiting the sustainable development of the wind power industry. More specifically, the traditional vibration data, which are easily disturbed by noises, cannot comprehensively characterize the health status; thus, the physical model is difficult to establish, and when the data-driven model analyzes the status, it results in unclear physical mechanisms. A new nonlinear Wiener degradation model was established based on the fusion of the physical models and the data-driven models, which was employed to characterize the degradation process of the slewing bearings in this work, and for the local temperature distribution, which has a strong anti-interference ability, the multi-sensor temperature data fusion was selected to analyze the RUL prediction. First, the multi-sensor temperature data were fused by performing a principal component analysis (PCA) to obtain the comprehensive health index (CHI), which represents the fan slewing bearings. Second, the Arrhenius Equation, which characterizes the degradation using temperature, was introduced into the nonlinear Wiener model, and a new degradation model was established. Moreover, considering the random change of the drift coefficients and the individual differences, the closed expression of the probability density function (PDF) of RUL was derived. Third, maximum likelihood estimation (MLE) was used to estimate the parameters. In addition, Bayesian analysis was used to update parameters to achieve real-time estimation. The results demonstrated that the proposed method can be used to significantly improve the fitting degree of the model and the accuracy of RUL estimation.
Concircular Vector Fields on Radical Anti-Invariant Lightlike Hypersurfaces of Almost Product-like Statistical Manifolds
Authors: Erkan Esra
Published: August 2023

The motivation of the present study is to describe the main relations of the radical anti-invariant lightlike hypersurfaces of almost product-like statistical manifolds. We provide concircular vector fields on radical anti-invariant lightlike hypersurfaces and obtain some results involving these vector fields.
Inducing Cytotoxicity in Colon Cancer Cells and Suppressing Cancer Stem Cells by Dolasetron and Ketoprofen through Inhibition of RNA Binding Protein PUM1
Authors: Gor Ravi , Gharib Ali , Dharshini Balaji Priya , Madhavan Thirumurthy , Ramalingam Satish
Published: August 2023

Clinical trials of new drugs often face a high failure rate of approximately 45 percent due to safety and toxicity concerns. Repurposing drugs with well-established safety profiles becomes crucial in addressing this challenge. Colon cancer ranks as the third most prevalent cancer and the second leading cause of cancer related mortality worldwide. This study focuses on the RNA-binding protein pumilio1 (PUM1), a member of the PUF family involved in post-transcriptional gene expression regulation. By utilizing molecular docking techniques and FDA-approved drugs, potential inhibitors against PUM1 were identified. Notably, dolasetron and ketoprofen demonstrated promising results, exhibiting strong binding affinity, hydrophobic interactions, and favorable chemical reactivity according to Conceptual-DFT calculations. Both compounds effectively reduced cell viability, with IC50 values of 150 µM and 175 µM, respectively and shows long term inhibitory effects as seen by reduced in number of colonies. Moreover, they exhibited inhibitory effects on colon cancer stem cells, as indicated by reduced colonospheroid size and numbers. Apoptosis is induced by these compounds and has triggered activation of executioner caspase 3/7 in HCT116 cells which is evident through a caspase 3/7 assay and AO/EB staining, while the non-toxic effect of these compounds was evident from viability against non-cancerous cell line and hemolysis assay. Additionally, the treatment group showed a significant decrease in PUM1 and cancer stem cell markers expression compared to the control group. In conclusion, this study highlights the potential of targeting PUM1 as a novel approach to colon cancer treatment. Dolasetron and ketoprofen demonstrate promise as effective anti-cancer and anti-cancer stem cell drugs, inducing apoptosis in colon cancer cells through inhibition of PUM1.
In Silico–Ex Vitro Iteration Strategy for Affinity Maturation of Anti-Ricin Peptides and the SPR Biosensing Application
Authors: Yang Zhifang , Wang Chuang , Liu Jia , Xiao Lan , Guo Lei , Xie Jianwei
Published: August 2023

The highly toxic plant toxin ricin is one of the most known threatening toxins. Accurate and sensitive biosensing methods for the first emergency response and intoxication treatment, are always pursued in the biodefense field. Screening affinity molecules is the fundamental mainstream approach for developing biosensing methods. Compared with common affinity molecules such as antibodies and oligonucleotide aptamers, peptides have great potential as biosensing modules with more accessible chemical synthesis capability and better batch-to-batch stability than antibodies, more abundant interaction sites, and robust sensing performance towards complex environments. However, anti-ricin peptides are so scant to be screened and discovered, and an advanced screening strategy is the utmost to tackle this issue. Here, we present a new in silico-in vitro iteration-assisted affinity maturation strategy of anti-ricin peptides. We first obtained affinity peptides targeting ricin through phage display with five panning rounds of “coating-elution-amplification-enrichment” procedures. The binding affinity and kinetic parameters characterized by surface plasmon resonance (SPR) showed that we had obtained four peptides owning dissociation constants (KD) around 2~35 μM, in which peptide PD-2-R5 has the lower KD of 4.7 μM and higher stable posture to interact with ricin. We then constructed a new strategy for affinity maturity, composing two rounds of in silico-in vitro iterations. Firstly, towards the single-site alanine scanning mutation peptide library, the molecular docking predictions match the SPR evaluation results well, laying a solid foundation for designing a full saturation mutated peptide library. Secondly, plenty of in silico saturation mutation prediction results guided the discovery of peptides PD2-R5-T3 and PD-2-R5-T4 with higher affinity from only a limited number of SPR evaluation experiments. Both evolved peptides had increased affinity by about 5~20 times, i.e., KD of 230 nM and 900 nM. A primary cellular toxicity assay indicated that both peptides could protect cells against ricin damage. We further established an SPR assay based on PD-2-R5-T3 and PD-2-R5-T4 elongated with an antifouling peptide linkage and achieved good linearity with a sensitivity of 1 nM and 0.5 nM, respectively. We hope this new affinity-mature strategy will find its favorable position in relevant peptide evolution, biosensing, and medical countermeasures for biotoxins to protect society’s security and human life better.
Has Data Quality of an Antimicrobial Resistance Surveillance System in a Province of Nepal Improved between 2019 and 2022?
Authors: Upadhaya Sweety , Acharya Jyoti , Zolfo Maria , Nair Divya , Kharel Mahesh , Shrestha Anjana , Shrestha Basudha , Madhup Surendra Kumar , Raghubanshi Bijendra Raj , Kattel Hari Prasad , Rajbhandari Piyush , Bhandari Parmananda , Thakur Subhash , Singh Gyani , Shrestha Lilee , Jha Runa
Published: August 2023

An operational research study was conducted in 2019 to assess the quality of data submitted by antimicrobial resistance (AMR) surveillance sites in the Bagmati Province of Nepal to the National Public Health Laboratory for Global Antimicrobial Resistance and Use Surveillance System (GLASS). Measures were implemented to enhance the quality of AMR surveillance by strengthening capacity, improving infrastructure, implementing data sharing guidelines, and supervision. The current study examined reports submitted by surveillance sites in the same province in 2022 to assess whether the data quality had improved since 2019. The availability of infrastructure at the sites was assessed. Of the nine surveillance sites in the province, seven submitted reports in 2022 versus five in 2019. Completeness in reporting improved significantly from 19% in 2019 to 100% in 2022 (p < 0.001). Timely reports were received from two sites in 2019 and only one site in 2022. Specimen–pathogen consistency in accordance with the GLASS guidelines for urine, feces, and genital swab specimens improved, with ≥90% consistency at all sites. Overall, the pathogen–antibacterial consistency improved significantly for each GLASS priority pathogen. The study highlights the importance of dedicated infrastructure and institutional arrangements for AMR surveillance. Similar assessments covering all provinces of the country can provide a more complete country-wide picture.
Lévy α-Stable Model for the Non-Exponential Low-|t| Proton–Proton Differential Cross-Section
Authors: Csörgő Tamás , Hegyi Sándor , Szanyi István
Published: August 2023

It is known that the Real Extended Bialas–Bzdak (ReBB) model describes the proton–proton (pp) and proton–antiproton (pp¯) differential cross-section data in a statistically non-excludible way, i.e., with a confidence level greater than or equal to 0.1% in the center of mass energy range 546 GeV ≤s≤8 TeV and in the squared four-momentum transfer range 0.37 GeV2 ≤ −t ≤ 1.2 GeV2. Considering, instead of Gaussian, a more general Lévy α-stable shape for the parton distributions of the constituent quark and diquark inside the proton and for the relative separation between them, a generalized description of data is obtained, where the ReBB model corresponds to the α=2 special case. Extending the model to α<2, we conjecture that the validity of the model can be extended to a wider kinematic range, in particular, to lower values of the four-momentum transfer −t. We present the formal Lévy α-stable generalization of the Bialas–Bzdak model and show that a simplified version of this model can be successfully fitted, with α<2, to the non-exponential, low −t differential cross-section data of elastic proton–proton scattering at s=8 TeV.
Search for Super-Deformed Identical Bands in the A = 190 Mass Region on the Basis of Level Spin
Authors: Jain Poonam , Kumar Yogesh , Kumar Vinod , Bangotra Pargin
Published: August 2023

The systematic study of Super-Deformed (SD) bands in the A=190 mass region has been performed. We observed a large number of pairs of SD bands, with different mass numbers, having transition energies nearly equal (within 3 keV) and having identical dynamic moments of inertia. The bands having nearly equal transitions energies and other parameters are called identical bands. We have performed detailed analysis and found 16 pairs of Super-Deformed Identical Bands (SDIBs) whose Eγ energies and moment of inertia are in good agreement with each other. The modified Variable Moment of Inertia (VMI) model is applied to 16 pairs of SDIBs to estimate the band spins by fitting the two parameters J0 and C. We found that out of 16 pairs, the band-head spin is consistent with moment of inertia and transition energies for four pairs. For another seven pairs, the transition energies and moment of inertia are identical, but originate from levels with different spins. The remaining five pairs have the identical energy but spins are either increasing or decreasing by one unit in the pair. Secondly, the NpNn scheme is applied to verify the existence of SDIBs. The parameters deduced from the NpNn scheme are also in good agreement for the mentioned case. The study indicates that each pair of conjugate nuclei have nearly identical spin, moment of inertia (dynamic) and gamma transition energy.
The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice
Authors: Skandorff Isabella , Gille Jasmin , Ragonnaud Emeline , Andersson Anne-Marie , Schrödel Silke , Thirion Christian , Wagner Ralf , Holst Peter Johannes
Published: August 2023

Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence Syncytin-1. Syncytin-1 is constitutively fusogenic and forms large multinucleated cell fusions when overexpressed. Consequently, immunising humans with a vaccine encoding Syncytin-1 can lead to the formation of extensive syncytia, which is undesirable and poses a potential safety issue. Here, we show experiments in cell lines that restoring an evolutionary lost cleavage site of the fusion inhibitory R-peptide of Syncytin-1 inhibit cell fusion. Interestingly, this modification of the HERV-W vaccine’s fusogenicity increased the expression of the vaccine antigens in vitro. It also enhanced Syncytin-1-specific antibody responses and CD8+-mediated T-cell responses compared to the wildtype vaccine in vaccinated mice, with a notable enhancement in responses to subdominant T-cell epitopes but equal responses to dominant epitopes and similar rates of survival following a tumour challenge. The impairment of cell–cell fusion and the enhanced immunogenicity profile of this HERV-W vaccine strengthens the prospects of obtaining a meaningful immune response against HERV-W in patients with HERV-W-overexpressing cancers.
Factors Associated with Utilization of Teleretinal Imaging in a Hospital-Based Primary Care Setting
Authors: Szulborski Kira J. , Gumustop Selin , Lasalle Claudia C. , Hughes Kate , Roh Shiyoung , Ramsey David J.
Published: August 2023

Regular eye examinations to screen for the initial signs of diabetic retinopathy (DR) are crucial for preventing vision loss. Teleretinal imaging (TRI) offered in a primary care setting provides a means to improve adherence to DR screening, particularly for patients who face challenges in visiting eye care providers regularly. The present study evaluates the utilization of TRI to screen for DR in an outpatient, hospital-based primary care clinic. Patients with diabetes mellitus (DM) but without DR were eligible for point-of-care screening facilitated by their primary care provider, utilizing a non-mydriatic, handheld fundus camera. Patient demographics and clinical characteristics were extracted from the electronic medical record. Patients who underwent TRI were more likely to be male, non-White, and have up-to-date monitoring and treatment measures, including hemoglobin A1c (HbA1c), microalbumin, and low-density lipoprotein (LDL) levels, in accordance with Healthcare Effectiveness Data and Information Set (HEDIS) guidelines. Our findings demonstrate that TRI can reduce screening costs compared to a strategy where all patients are referred for in-person eye examinations. A net present value (NPV) analysis indicates that a screening site reaches the break-even point of operation within one year if an average of two patients are screened per workday.
HYPER: Computer-Assisted Optimal Pump-as-Turbine (PAT) Selection for Microhydropower Generation and Pressure Regulation in a Water Distribution Network (WDN)
Authors: Marini Gustavo , Di Menna Francesco , Maio Marco , Fontana Nicola
Published: August 2023

Although pressure reducing valves (PRVs) have traditionally been employed to regulate pressure and reducer water leakage, researchers have been increasingly investigating the strategy of micro-hydropower generation using pumps as turbines (PATs) to enable both pressure reduction and energy production as an alternative strategy in water distribution networks (WDNs). However, due to the continuous variability of flow discharge during the day, selecting the optimal PAT remains a challenging issue. To address this, the authors have developed HYPER, a freely available software app that implements an innovative approach for selecting the most suitable PAT in systems that involve both hydraulic and/or electrical regulation. In enabling the identification of the PAT parameters that maximize energy production, HYPER thus provides a fast and effective PAT selection tool. The effectiveness of the proposed approach was further demonstrated with application to a real WDN. Four operational patterns varying in terms of available flow and head drop were considered, showing that the most efficient pumps consistently tended to be located in close proximity to the maximum produced energy. Furthermore, the results confirmed that hydraulic regulation and coupled hydraulic/electric regulation-based installation layouts represent the best solutions in terms of energy produced. The solely electrical regulation option, given its poor flexibility, returns in all cases lower energy production with the lower adaptability of commercial pumps.
The Base Value of the Ecological Compensation Standard in Transboundary River Basins: A Case Study of the Lancang–Mekong River Basin
Authors: Zhao Yue , Li Fang , Chen Yanping , Chen Xiangnan , Xu Xia
Published: August 2023

The ecological compensation standard in transboundary river basins should be determined by the basin countries through negotiation on the basis of the base value of the ecological compensation standard. This paper calculated the base value range of the ecological compensation standard, determining the upper limit based on the spillover value of ecosystem services for the ecosystem-service-consuming country and the lower limit according to the cost of ecological protection for the ecosystem-service-supplying country. The final range was determined by integrating this with the willingness to pay and the actual effort in each basin country. Taking, for example, the Lancang–Mekong River basin, the results indicate that the spillover value of ecosystem services in Laos, China and Myanmar was positive and these three countries were ecosystem-service-supplying countries, while in Cambodia, Vietnam and Thailand it was negative and these three countries were ecosystem-service-consuming countries. Among the ecosystem-service-supplying countries, the cost of ecological protection of them was in descending order of Laos, China and Myanmar, which was related to their own level of economic development. Considering the adjustment coefficient for the payment of ecosystem service value and the cost-sharing coefficient of each basin country, the feasible range for the base value of the ecological compensation standard was determined to be [2.47, 229.67] × 108 $, which provided the basis for the negotiation on the determination of the ECS. In addition, implementation suggestions were proposed from three aspects: establishing a basin-information-sharing mechanism and platform, establishing an integrated management organization for transboundary river basins, and strengthening and improving the coordination and supervision model of ecological compensation.
Early and late facial neuropathy after radiosurgery of vestibulocochlear schwannomas
Authors:   SBHI N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Gretskikh K.V. , Zavaliy L.B. ,   SBHI N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Evdokimova O.L. ,   SBHI N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Shamalov N.A. ,   Institute of Cerebrovascular Pathology and Stroke, FSBI Federal Center for Brain and Neurotechnologies of the Federal Medical and Biological Agency of Russia, Petrikov S.S. ,   SBHI N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department
Published: August 2023

Stereotactic radiosurgery (SRS) is the method of choice for the treatment of vestibular schwannomas, due to its high frequency of tumor growth control and low complication rate. According to the world scientific literature, one of the rare late radiation induced complications is facial nerve paralysis. It is extremely rare to find reports of cases of prosoparesis that occurred during the first week after performing SRS. The potential etiology, pathogenesis, and management of this type of complication still remain a subject for discussion. As potential risk factors for the development of radiation-induced complications for cranial nerves, such indicators as the patient's age, the maximum diameter of the tumor, the presence of a fundal fluid cap, the amount of prescribed, average and maximum radiation dose per cochlea, the extent of the tumor's contact with the nerve trunk, or the radiation dose beyond the boundaries of the tumor are currently being studied. However, further study of predictors of the post-radiation neuropathy requires cohort studies. The article presents two cases of early and late radiation-induced neuropathy of the facial nerve after radiosurgery of vestibular schwannomas. Predictors and risk factors for the development of this type of complications after SRS are discussed. The important role of steroid therapy in the complex treatment of this group of patients was noted. In the presented patients, no reliable pathogenetic mechanisms leading to early radiation damage to the facial nerve were revealed. Despite the restoration or improvement of the strength of facial muscles, complications of facial neuropathy (hypertension, synkinesia) developed, which required timely detection and correction with the mandatory supervision of a neurologist.
Use of anticoagulants in patients with traumatic brain injury and intracranial hematomas with the novel coronavirus infection as a concomitant pathology
Authors:   FSBEI HE Pediatric Saint-Petersburg State Medical University named after I. P. Pavlov of the Ministry of Health of Russia, Cherebillo V. Yu. , Kanarskiy A. D. ,   FSBEI HE Pediatric Saint-Petersburg State Medical University named after I. P. Pavlov of the Ministry of Health of Russia, Sosnovski A. S. ,   FSBEI HE Pediatric Saint-Petersburg State Medical University named after I. P. Pavlov of the Ministry of Health of Russia, Kurnukhina M. Yu. ,   FSBEI HE Pediatric Saint-Petersburg State Medical University named after I. P. Pavlov of the Ministry of Health of Russia, Chernichenko V. K. ,   FSBEI HE Pediatric Saint-Petersburg State Medical University named after I. P. Pavlov of the Ministry of Health of Russia
Published: August 2023

Anticoagulant therapy is an integral part in the treatment and prevention of diseases and symptoms associated with pathological thrombosis in the human body. Anticoagulant therapy is traditionally not used in traumatic brain injury and hemorrhagic strokes with the formation of intracranial hematomas, intracerebral hematomas, and contusion hemorrhagic foci. However, in such diseases as the novel coronavirus infection, anticoagulant therapy is life-saving, since there is a high risk of developing various thromboses. The article considers the indications for the prescription of anticoagulants in the combination of these pathologies. The article discusses the possibility of using anticoagulants in patients with the novel coronavirus infection and intracranial hematomas, when there are two life-threatening diseases, in which anticoagulants are vital in one case and contraindicated in the other one. It is necessary to understand the complex mechanisms of hemostasis and weigh the risks and benefits in each case.
Comorbidity of schizophrenia and alcoholism in the modern paradigm of outpatient psychiatric care
Authors:   Psychiatric Clinical Hospital No. 1 named after N. A. Alekseev, Cherepakhin D. I. ,   Moscow, Aronov P. V. ,   Federal Scientific and Clinical Center of Specialized types of Medical Care and Medical Technologies; Moscow
Published: August 2023

The comorbidity of alcohol disorder and schizophrenia or schizoaffective disorder is a complex and multifaceted problem that has a significant impact on the quality of life of patients and the complexity of medical care. This article discusses the common neurobiological mechanisms that explain the high rates of co-occurrence of these disorders, as well as the consequences of such comorbidity for patients and the healthcare system. Additionally, potential ways to optimize the treatment of these patients are being considered.
Prescripción de ejercicios de rehabilitación cardiaca en pacientes con Tetralogía de Fallot y sus beneficios en pacientes adolescentes y adultos jóvenes
Authors: Álvarez-Cordero Dayna , Vargas-Vargas Amanda , Rivera-Vargas Juan Miguel
Published: August 2023

Introducción: la Tetralogía de Fallot (ToF) es una cardiopatía congénita que presenta cuatro distintas afecciones: estenosis en el tracto de la salida del ventrículo derecho, una comunicación interventricular grande y no restrictiva, hipertrofia del ventrículo derecho y cabalgamiento o dextro posición de la aorta. Esta patología se determina por el grado de obstrucción en el tracto de salida en el ventrículo derecho, ocasionando cianosis. Objetivo: describir la adecuada prescripción de ejercicios de rehabilitación cardiaca en pacientes con Tetralogía de Fallot y sus beneficios en pacientes adolescentes y adultos jóvenes. Metodología: se realizó una revisión bibliográfica sistematizada de tipo narrativa consultando en las bases de datos EBSCO, PubMed, Scielo, Elsevier y Redalyc, artículos científicos publicados entre el año 2016 y 2022, en idioma español o inglés. Los descriptores utilizados fueron: tetralogía de Fallot, ejercicio físico/ejercicio aeróbico/ ejercicio de resistencia/, rehabilitación cardíaca, calidad de vida y contraindicaciones, y sus iguales en idioma inglés. Se encontraron un total de 59 artículos, se excluyeron artículos repetidos y los que no mencionan la relación entre la rehabilitación cardíaca en pacientes con ToF; se incluyeron un total de 33 artículos. Resultados:  los niños que nacen con ToF, deben someterse a una cirugía correctiva, la cual ocasiona una disminución en la capacidad de ejercicio, afectando su calidad de vida y autonomía en su vida adulta. Sin embargo, las intervenciones de rehabilitación cardíaca garantizan a los pacientes mejores condiciones físicas (sistema cardiorrespiratorio y fuerza), mentales (disminución de ansiedad y depresión) y sociales (participación, rendimiento académico). Los programas de ejercicio tienen que ser individualizados para los pacientes con cardiopatías congénitas, estos programas deben de ser sin restricciones excesivas en el ejercicio físico ni ejercicio excesivo, tomando en cuenta la clasificación del riesgo del paciente y una serie de valoraciones previas a la prescripción. Una frecuencia de ejercicio de dos veces por semana, en comparación directa entre los índices de carga de trabajo, pico de VO2 (consumo de oxígeno), pulso de O2, pico de trabajo y tiempo de resistencia, brinda mejor aprovechamiento. Conclusiones: la rehabilitación cardíaca resulta beneficiosa en pacientes con ToF y se basa en la prescripción de ejercicio aeróbico y resistencia con el fin de obtener mejoras en la condición física y en la aptitud cardiorrespiratoria. Ésta es segura y no demuestra complicaciones siempre que se maneje de manera individual y se realicen las debidas evaluaciones.
Terapia física en la prevención de los problemas de salud mental durante el envejecimiento
Authors: Montoya-Valverde Denis , Marchena-Mora Tania , Fajardo-Lui Adrian , Roselló-Araya Marlene , Cyrus-Barker Ericka
Published: August 2023

Objetivo: describir el impacto de la terapia física en la prevención de los principales problemas de salud mental asociados con el proceso de envejecimiento. Metodología: revisión bibliográfica, en la cual se comprendieron artículos del 2017 al 2022, en español e inglés, que incluyeran personas mayores de 65 años, de tipo revisiones bibliográficas, revisiones sistemáticas, estudios cualitativos, estudios observacionales y ensayos clínicos. Se obtuvieron 31 artículos científicos mediante la búsqueda en bases de datos EBSCO host, SciELO y PubMed. La estrategia utilizada de la combinación en los descriptores fue: salud mental en la persona adulta mayor, factores de la salud mental, actividad física en la persona adulta mayor, terapia física y salud mental. De acuerdo con el nivel de evidencia se clasificaron en: revisión sistemática de ensayos controlados aleatorios (19%), revisión sistemática de estudios de cohorte (23%), revisión sistemática de estudios caso control (19%), estudios transversales (29%), opinión de expertos (10%). Resultados: la investigación evidenció que los factores que se relacionan con los principales problemas de salud mental en personas mayores de 65 años son aquellos de origen biológico, patológico y social, que contribuyen a la disminución de las reservas del organismo, lo cual puede ser tratado por medio de intervenciones fisioterapéuticas como lo son el movimiento funcional, la actividad física, la prescripción del ejercicio y la conciencia cinemática. Las intervenciones deben centrarse en un enfoque multimodal, que incluya ejercicios aeróbicos, resistencia, marcha, equilibrio, de intensidad moderada a vigorosa, junto a espacios para el ocio y el esparcimiento donde se pueda incluir actividades de la vida diaria que permitan promover el movimiento funcional y la conciencia cinemática; actividades como la terapia de conciencia corporal basal, terapia de movimiento de baile, musicoterapia, el yoga y el Tai Chi son algunas de las intervenciones que más resultados positivos han demostrado. Conclusiones:  la fisioterapia puede ayudar a los pacientes a mejorar su estado de ánimo, disminuir la ansiedad, mejorar la calidad de vida y reducir los síntomas de los trastornos mentales a través de la conciencia del movimiento corporal y el ejercicio.
Colaborando en un mundo en transición, Academia Latinoamericana de Desarrollo Infantil y Discapacidad (ALDID)
Authors: Valdelomar-Marín Erick , De Campos Ana Carolina , Longo Egmar , Ribeiro-Leite Hércules , Pessóta-Sudati Isabella , Souto Deisiane , Valerín-Ramírez Roselyn
Published: August 2023

La Academia Latinoamericana de Desarrollo Infantil y Discapacidad (ALDID) es una organización interdisciplinaria de profesionales latinoamericanos sin fines de lucro, que promueve el desarrollo integral de los niños, niñas y adolescentes y sus familias por medio del avance de la investigación, la promoción de prácticas clínicas basadas en la evidencia, la educación continua, y la promoción de los derechos de niños con trastornos en el desarrollo y/o discapacidad y sus familias. Visando disminuir las barreras para el acceso a las practicas basada en evidencia y al conocimiento sobre desarrollo infantil y discapacidad, ALDID ha promovido congresos científicos y varias acciones de traducción de conocimiento. El IV Congreso ALDID permitió reunir a profesionales de la salud y la educación, representantes del Estado (Salud, Educación, Social) y Sociedad Civil (ONG, Familias y Personas con Discapacidad) para demostrar los avances científicos en el campo de la discapacidad infantil como puente para asegurar una calidad y participación plena en la vida de los niños y jóvenes con discapacidad. ¡ALDID invita a todos los profesionales a unir esfuerzos para que podamos avanzar más fuertes hacia el futuro y seguir colaborando en un mundo en transición!
Structuring of economic analysis based on the criterion of the volume of data used
Authors: Kornyushchenko Andrey V.
Published: August 2023

The article analyzes the main approaches to structuring economic analysis, justifies the author's approach using a grouping feature – the type of data used. The concept of economic analysis is considered at the microeconomic level, in this case the object of observation is an organization (enterprise). As the main criteria determining the structure of economic analysis, the requests of stakeholders and the sources of information used are highlighted. According to the author, not enough attention is paid to the classification of data (financial and non-financial) in the economic analysis of the organization's activities in the scientific literature, which does not allow for a clear separation of managerial and financial, external and internal analysis. Special attention is paid to deciphering the concepts of financial and managerial analysis.
Investment decisions in the real estate market using instruments to reduce the level of financial risks
Authors: Buneeva Evgeniya Yu. , Bezrukikh Olga A. , Zubritskaya Kseniya Yu.
Published: August 2023

The real estate market is an important element of the system of market relations, acting not only as an object of ownership, but also as an object of investment. Real estate investments are one of the key aspects of ensuring the functioning of the economic system and have a multiplicative effect. The article substantiates the role of real estate investments as the most important catalyst for economic development. The structure and dynamics of investments in commercial real estate were analyzed, which led to the conclusion that the overall increase in the volume of investments in this market is accompanied by a reduction in the share of foreign capital in investments. Various forms of investment are considered and their distinctive features are investigated in the context of the fundamental characteristic features of each of the forms. Special attention is paid to investment decisions related to investments in real estate and implemented using financial market instruments. Based on a number of characteristics, the presented forms of investment were compared, their profitability, growth prospects and possible risks were determined. Based on the analysis, the directions of investment strategies in the real estate market are formulated, which are relevant in the current market conditions.
Best Management Practices for a Successful Transition into an Administrative Role
Authors: Godwin Derek , Diem Keith , Maddy Deborah
Published: August 2023

Many successful county Extension educators aspire to "higher" positions in administration, such as a county director, regional director, etc. However, such administrative roles likely have more complex duties related to managing people and teams than faculty have experienced in their program assignment. This article provides essential management concepts and techniques to help faculty gain perspective and build a foundation for success in transitioning to an administrative assignment. Best management practices are shared that can significantly improve administrators' leadership skills and the likelihood of success in managing faculty and staff to maintain a productive, positive, and supportive office environment.
Financial Management and Relationship Skills Education: Gauging Consumer Interest and Delivery Preferences
Authors: Futris Ted , Nielsen Robert , Barton Allen
Published: August 2023

The study reported here explored level of interest and preferred delivery method of Extension programming related to financial management and relationship skills education. These two subjects comprise areas of Extension that often receive less recognition but appear as pertinent issues in the lives of many individuals. Using a diverse sample of 512 residents from the state of Georgia, findings from the study indicate high levels of interest for receiving information in both program areas. Additionally, findings highlight how delivery method preferences depend on both the particular audience and particular content areas.
A User Evaluation of a Decision-Support System: The Community Assessment Model for Odor Dispersion (CAM)
Authors: Tyndall John , Harmon Jay , Hoff Steven , Schuck Nancy
Published: August 2023

This article introduces to the agricultural Extension community a decision-support system—the Community Assessment Model for Odor Dispersion (CAM)—that is helping Iowa swine producers minimize potential odor conflict. Additionally, we share our rationale and approach to evaluating both CAM and its outreach approach. CAM accounts for local conditions and helps producers assess odor risk from new facilities. Based on a user survey, 75% of producers rated CAM as "useful" to "very useful" in decision-making. Results suggest that CAM has passed the primary test of applied science as measured by usefulness to producers in making better decisions.
Perceptions of Missouri 4-H Youth Development Personnel Regarding Interorganizational Cooperative Behavior
Authors: McKim Billy , Torres Robert
Published: August 2023

Perceptions of 4-H youth development personnel regarding interorganizational cooperation were studied between the perceived and desired levels of cooperative activities between 4-H youth development personnel and secondary agriculture teachers. Results indicated that 4-H youth development personnel wanted higher levels of coordinated efforts between the organizations and to utilize the resources provided by secondary agriculture teachers. Despite the desire of 4-H youth development personnel to participate in interorganizational cooperation, their perceived level of cooperation was lower than that of their desired level.
Extension's Role in Urban Education: Why Aren't We Involved?
Authors: Smith Kenyatta
Published: August 2023

With education failing nationwide and economic restraints affecting both rural and urban educational institutions, Extension should be taking a more aggressive stance instead of operating in what has now become the way of Extension and "collecting numbers." Why isn't Extension more visible in the urban populations that reside in our own backyards? This article is a cry out for a clear understanding of where Extension is in today's world and how we must change to survive and flourish amidst changing cultures.
Detergent Considerations for Consumers: Laundering in Hard Water—How Much Extra Detergent Is Required?
Authors: Camerson Bruce
Published: August 2023

Laundering is a complex process, and detergents have changed considerably over the last 20 years. The research reported will be of benefit to both Extension educators and teachers in advising people with whom they work on choices between different types of laundry detergents when it comes to laundering. Liquid detergents washed equally well in both soft and hard water. Powdered detergents were better than liquids in soft water. Water hardness affected powdered detergents, and, depending on the detergent type, 10-15% to > 30% extra detergent was needed to obtain a result similar to that of soft water.
Are You Ready to Be an Administrator? A Self-Assessment to Help You Manage Expectations When Assuming a New Role
Authors: Diem Keith
Published: August 2023

As a county Extension educator is successful and matures, it is natural for him or her to seek advancement to an administrative position. However, such a role likely has more complex duties related to managing people than the faculty member may have experienced or been trained to address in his or her program assignment. This article outlines some of the differences in duties and perspective that may be encountered when changing from a program-driven faculty member position to one with administrative leadership duties in the form of a self-assessment that may help determine whether you're ready to serve in an administrative role.
Action Learning—An Experiential Tool for Solving Organizational Issues
Authors: Kinsey Sharon
Published: August 2023

Action Learning can be effectively used in both large and small businesses and organizations by employees, stakeholders, or volunteers through this "learning by doing" approach to evaluate an issue or issues of importance to the organization. First developed in the 1940s, Action Learning has increasingly been used as a method to explore questions that often go unanswered in day-to-day organizational life through the use of reflective listening and insightful questioning.
Simple Retirement Plan Options for Small Agricultural and Forestry Operations
Authors: Straka Thomas
Published: August 2023

Many family farm and forests are small operations with just a few employees. Retaining these employees can be difficult, and a retirement package can make a big difference in employee job satisfaction. Extension professionals ought to be aware of several simple individual retirement account options available that minimize administrative costs and paperwork. The advantages of tax deferral in retirement planning are explained. The simplified employee pension (SEP) individual retirement arrangement (IRA) and the SIMPLE IRA are described. Examples are provided of typical savings from these programs and sources for additional information are identified.
Assisting with Ecological Land Planning: Introducing the Conservation Subdivision Ecological Design and Site Assessment Toolkit
Authors: Göçmen Asligül , Gao Jing
Published: August 2023

Geospatial tools can be helpful in the practice of land use and environmental planning. This article introduces an easy-to-use and cost-free geospatial toolkit that was created to help with the ecological design and evaluation of (open space) conservation subdivision proposals. The article describes the ecological design and site assessment functions and discusses how Extension educators might use it to help planning-related professionals conduct ecological planning in their communities.
Three Simple Hands-On Soil Exercises Extension Professionals Can Incorporate into Natural Sciences Curriculum
Authors: Kleinschmidt Andy
Published: August 2023

The importance of healthy soil and of conveying the importance of soils starts by conveying a few basic concepts of soil science cannot be overstated. This article provides three hands-on exercises Extension professionals can add to natural resources or Master Gardener education curricula. These natural sciences exercises are easy to prepare for the instructor and accurately reflect behavior of soil in situ. These exercises are designed for classroom use, but they can be used concurrently with field training. These exercises are appropriate for both youth and adult audiences.
A Snapshot of Organizational Climate: Perceptions of Extension Faculty
Authors: Tower Leslie , Bowen Elaine , Alkadry Mohamad
Published: August 2023

This article provides a snapshot of the perceptions of workplace climate of Extension faculty at a land-grant, research-high activity university, compared with the perceptions of non-Extension faculty at the same university. An online survey was conducted with a validated instrument. The response rate for university faculty was 44% (968); the response rate for Extension was 77% (126). Perceptions of the workplace climate were in the high-to-moderate range. Extension faculty appeared to view campus climate more favorably than traditional faculty. This article calls attention to the benefits of assessing an organization's climate.