bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Genetics of Parkinsonism
Authors: Lesage Suzanne , Brice Alexis
Published: May 2010

Over the past decade, genetic causes of parkinsonism have been elucidated, but in less than 10% of the cases. Since the discovery of the first gene responsible for Parkinson disease (PD),

SCNA

encoding
α‐synuclein
, linkage mapping and positional cloning have identified autosomal dominantly or recessively inherited PD‐causing mutations in the genes encoding
parkin
,
PTEN‐induced kinase 1
(

PINK1

),
DJ‐1
,
leucine‐rich repeat kinase 2
(

LRRK2

) and
ATP13A2
, indicating that PD has a highly heterogeneous aetiology. In addition, polymorphic variants in

SNCA

and

LRRK2

and heterozygous mutations in the gene encoding
β‐glucocerebrosidase
(

GBA

) appear to contribute to sporadic PD in several populations. These mutations have been linked to mitochondrial dysfunction, accumulation of abnormal and misfolded proteins, impaired protein clearance and oxidative stress. Identification of other mendelian forms of PD will be the main challenge for the next decade.

Key concepts:

Deciphering the aetiology of monogenic forms of parkinsonism would help understanding of the common idiopathic forms of the disease.

Genetic dissection of familial parkinsonism provides clues in identifying pathways involved in neuronal death.

The knowledge of the pathogenesis of Parkinson disease at a molecular level will have important implications for the development of individual therapeutic strategies to prevent disease progression.

Linkage analysis and positional cloning are fundamental tools for identifying genes in inherited diseases.

Genome‐wide association studies provide a powerful tool to identify low penetrance at‐risk alleles.
The Genetics of Human Aggressive Behaviour
Authors: Craig Ian W , Halton Kelly E
Published: May 2010

Both genes and environment contribute to individual differences in aggression. Surveys of the pathways implicated in the physiological and neuronal processes involved highlight the potential role of genes regulating sexual differentiation, anxiety, stress response and neurotransmission. To date, however, association studies have provided little evidence of a substantially significant role for any single candidate gene in such pathways. This may be because genes function against a background in which other genetic and environmental factors are crucial. A series of recent studies, particularly concentrating on
monoamine oxidase A
, has emphasised the necessity of examining gene by environmental interactions if the contributions of individual loci are to be understood. These findings have major significance for the interpretation of data, both from individual gene and whole genome association studies. Functional imaging studies of genetic variants affecting serotonin pathways have also provided valuable insights into potential links between genes, brain and aggressive behaviour.

Key Concepts:

Aggression is an evolutionarily advantageous trait with input from one of the most primitive brain regions, the amygdala.

There is significant disparity between aggressive behaviour in males and females.

Genes and environment both influence aggressive behaviour and there is evidence that stressful life events can interact with specific genetic variants.

DBH
,
COMT
, adrenergic receptors,
NET1
and
SLC6A2
have been studied as possible candidate genes linking stress and aggression.

In the serotonin system, genetic polymorphisms in
MAOA
,
SLC6A4
,
TPH1/2
and the serotonin receptor genes have been linked with aggression.

Studies have shown a potential link between diet and its effects (e.g. on glucose levels) and aggression.

Brain imaging studies are beginning to assist an interpretation of the links between genetic variation and aggression.
On the Symmetry of the n=1 Ruddlesden‐Popper Phase Ca2FeO3Cl.
Authors: Kriworuschenko B. , Kahlenberg V.
Published: May 2010

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Rb(GaPO4)2(OH)(H2O)×H2O: A Hydrated Rubidium Gallium Phosphate Analogue of GaPO4×2H2O and Leucophosphite.
Authors: Beitone Lionel , Loiseau Thierry , Ferey Gerard
Published: May 2010

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Growth of Nd:GdVO4 Single Crystal and Its Laser Output at 1062 nm, 1342 nm.
Authors: Qin L. J. , Meng X. L. , Du C. L. , Shao Z. S. , Zhu L. , Xu B. C. , Zhang H. J.
Published: May 2010

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Flux Growth of Vanadyl Pyrophosphate, (VO)2P2O7, and Spin Dimer Analysis of the Spin Exchange Interactions of (VO)2P2O7 and Vanadyl Hydrogen Phosphate, VO(HPO4)×0.5H2O.
Authors: Koo Hyun‐Joo , Wangbo Myung‐Hwan , VerNooy Paul D. , Torardi Charlie C. , Marshall William J.
Published: May 2010

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Formation of Ternary Carbide Co6W6C by Mechanical Activation Assisted Solid‐State Reaction.
Authors: Tsuchida Takeshi , Morita Naruki
Published: May 2010

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Single‐Crystal Al18B4O33 Microtubes.
Authors: Ma Renzhi , Bando Yoshio , Sato Tadao , Tang Chengchun , Xu Fangfang
Published: May 2010

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Dichlorogallane (HGaCl2)2: Its Molecular Structure and Synthetic Potential.
Authors: Nogai Stefan , Schmidbaur Hubert
Published: May 2010

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Mg2+‐Selective Fluorescence Enhancement of Benzo‐15‐crown‐5 Derivative Bearing Vinylanthracene Fluorophore.
Authors: Shin Eun Ju
Published: May 2010

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Kinetic Resolution of Oxime Esters with Lipases — Synthesis of Enantiomerically Enriched Building Blocks with Quaternary Carbon Centers and Formal Total Synthesis of Perhydro Histrionicotoxin.
Authors: Diedrichs Nicole , Krelaus Ralf , Gedrath Ina , Westermann Bernhard
Published: May 2010

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First Chemoenzymatic Synthesis of Optically Active Uracil and Chromen‐4‐one Substituted Homoallylic Alcohols: An Entry into Chiral Pool.
Authors: Singh Satwinder , Kumar Subodh , Chimni Swapandeep Singh
Published: May 2010

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Biomimetic Reactions in Organic Synthesis: Semi‐pinacol Rearrangements of Some Spirocyclic Epoxyalcohols Derived from Julia—Colonna Asymmetric Epoxidations.
Authors: Hauer Bernhard , Bickley Jamie F. , Massue Julien , Pena Paula C. A. , Roberts Stanley M. , Skidmore John
Published: May 2010

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Synthesis of Allylic Esters and Ethers Using Polymer‐Supported Selenium Bromide.
Authors: Sheng Shou‐Ri , Huang Xian
Published: May 2010

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Bi3+ Catalyzed Regioselective Ring Opening of Epoxides with Aromatic Amines.
Authors: Swamy N. Raghavendra , Kondaji G. , Nagaiah K.
Published: May 2010

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Synthesis of Substituted Azines with the Participation of 4‐Bromo‐5‐nitrophthalonitrile.
Authors: Abramov Igor G. , Zhandarev Valerii V. , Smirnov Alexey V. , Kalandadze Levan S. , Goshin Mikhail E. , Plakhtinskii Vladimir V.
Published: May 2010

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MIMIRC Reactions of Nitromethane with Electrophilic Alkenes in Solvent‐Free Reactions under Microwave Irradiation.
Authors: Michaud David , Hamelin Jack , Texier‐Boullet Francoise , Toupet Loic
Published: May 2010

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Improvement of a Biomimetic Porphyrin Catalytic System by Addition of Acids.
Authors: Segrestaa Jerome , Verite Philippe , Estour Francois , Menager Sabine , Lafont Olivier
Published: May 2010

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A New Efficient Synthesis of ortho‐Cyanoarenes via Directed Lithiation Followed by Electrophilic Cyanation.
Authors: Sato Nobuhiro
Published: May 2010

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Prop‐2‐yn‐1‐als and 1‐Phenylprop‐2‐yn‐1‐one in the Chalcogen Baylis—Hillman Reaction.
Authors: Medvedeva Alevtina S. , Demina Maria M. , Novopashin Peter S. , Sarapulova Galina I. , Afonin Andrei V.
Published: May 2010

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Microwave‐Assisted Condensation Reactions Exploiting Hexamethylenetetramine as a Catalyst under Solvent‐Free Conditions.
Authors: Karchgaudhuri Nilay , De Aparna , Mitra Alok Kumar
Published: May 2010

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Tandem Oxidation Processes: The Direct Conversion of Activated Alcohols into Esters and Amides.
Authors: Foot Jonathan S. , Kanno Hisashi , Giblin Gerard M. P. , Taylor Richard J. K.
Published: May 2010

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A Convenient Oxidative Demasking of 1,3‐Dithiolanes and Dithianes to Carbonyl Compounds with TBHP.
Authors: Barhate Nivrutti B. , Shinde Popat D. , Mahajan Vishal A. , Wakharkar Radhika D.
Published: May 2010

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Conversion of Oximes, Phenylhydrazones, 2,4‐Dinitrophenylhydrazones and Semicarbazones to Carbonyl Compounds with Benzyltriphenylphosphonium Chlorochromate (BTPPCC) in the Presence of Aluminum Chloride under Non‐aqueous Conditions.
Authors: Hajipour Abdol Reza , Mallakpour Shadpour E. , Mohammadpoor‐Baltork Iraj , Backnejad Hossein
Published: May 2010

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Stereoselective Synthesis of syn,syn‐2‐Methyl‐1,3‐diols Through One‐Pot Aldol—Reduction Sequence.
Authors: Galobardes Marta , Mena Marisa , Romea Pedro , Urpi Felix , Vilarrasa Jaume
Published: May 2010

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A One‐Pot, Two‐Step Enzymatic Synthesis of L‐Lactic Acid from Acetaldehyde.
Authors: Miyazaki Masaya , Ogino Kazuya , Shibue Mitsukuni , Nakamura Hiroyuki , Maeda Hideaki
Published: May 2010

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Michael Addition of N,N′‐Dibenzylmalonamide to N‐Aryl(alkyl)crotonamides.
Authors: Georgiyants V. A. , Bezuglyi P. A. , Perekhoda L. A.
Published: May 2010

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Highly Enantioselective Copper—Bisoxazoline‐Catalyzed Allylic Oxidation of Cyclic Olefins with tert‐Butyl p‐Nitroperbenzoate.
Authors: Andrus Merritt B. , Zhou Ziniu
Published: May 2010

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Synthesis of Eight‐ and Nine‐Membered Carbocycles Through a Ring‐Closing Metathesis/Ring Fragmentation Strategy: A Rapid and Versatile Approach to Bicyclo[6.4.0]‐ and Bicyclo[7.4.0]alkene Ring Systems.
Authors: Rodriguez J. Ramon , Castedo Luis , Mascarenas Jose L.
Published: May 2010

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Can We Aminate Grignard Reagents under Barbier Conditions?
Authors: Erdik Ender , Daskapan Tahir
Published: May 2010

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Synthesis and Characterization of 1,3‐Bis‐(2,4,6‐trichlorophenyl)‐1H‐triazene (BTCPT).
Authors: Mehilal Mehilal , Salunke Rajendra B. , Agrawal J. P.
Published: May 2010

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A Practical Synthesis of Chloromethyl Esters from Acid Chlorides and Trioxane or Paraformaldehyde Promoted by Zirconium Tetrachloride.
Authors: Mudryk Boguslaw , Rajaraman Shanthi , Soundararajan Nachimuthu
Published: May 2010

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Suzuki—Miyaura Cross‐Coupling Reactions Mediated by Palladium/Imidazolium Salt Systems.
Authors: Grasa Gabriela A. , Viciu Mihai S. , Huang Jinkun , Zhang Chunming , Trudell Mark L. , Nolan Steven P.
Published: May 2010

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Single Step Synthesis of Cyclooctadienone Derivatives by Reaction of Cyclobutenones with Dienyllithium.
Authors: Hamura Toshiyuki , Tsuji Shinsuke , Matsumoto Takashi , Suzuki Keisuke
Published: May 2010

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The “Photo‐Friedel—Crafts Acylation” of 1,4‐Naphthoquinones.
Authors: Oelgemoeller Michael , Schiel Christian , Froehlich Roland , Mattay Jochen
Published: May 2010

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Diastereoselective Aziridination of Chiral α‐Carbonyl Enoates.
Authors: Fioravanti Stefania , Morreale Alberto , Pellacani Lucio , Tardella Paolo A.
Published: May 2010

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Novel 2‐Thioxohydantoin Ketene Dithioacetals: Versatile Intermediates for Synthesis of Methylsulfanylimidazo[4,5‐c]pyrazoles and Methylsulfanylpyrrolo[1,2‐c]imidazoles.
Authors: Elgemeie Galal H. , Elghandour Ahmed H. , Ali Hosny A. , Hussein Ahmed M.
Published: May 2010

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Highly Stereocontrolled [2 + 2] Cycloaddition versus Unprecedented Imino‐Ene Reactions of Imino‐Ketenimines.
Authors: Alajarin Mateo , Vidal Angel , Tovar Fulgencio , Sanchez‐Andrada Pilar
Published: May 2010

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Palladium‐ and Copper‐Catalyzed Selective Arylation of 5‐Aryltetrazoles by Diaryliodonium Salts.
Authors: Beletskaya Irina P. , Davydov Dmitri V. , Gorovoy Matvey S.
Published: May 2010

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A Convenient One‐Pot Synthesis of 2‐(Alkylthio)isoflavones from Deoxybenzoins Using a Phase Transfer Catalyst.
Authors: Kim Young‐Woo , Brueggemeier Robert W.
Published: May 2010

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Quinonimine Formation in the Reaction of 6‐Hydroxy‐2,2,4‐trimethyl‐1,2‐dihydroquinoline with 1‐Chloro‐2,3‐epoxypropane.
Authors: Shmyreva Zh. V. , Ponomareva L. F.
Published: May 2010

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Dimethyl Sulfoxide‐Promoted Dehydrosulfonylation of 2‐Aryl‐3‐bromo‐1‐methanesulfonyl‐2,3‐dihydroquinolin‐4(1H)‐ones.
Authors: Mphahlele Malose J.
Published: May 2010

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Straightforward Synthesis of 11H‐Indolo[3,2‐c]isoquinoline and Benzofuro[3,2‐c]isoquinoline by Ring Transformation.
Authors: Beres Mariann , Timari Geza , Hajos Gyoergy
Published: May 2010

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Synthesis and Cytotoxic Activities of Pyrrole[2,3‐d]pyridazin‐4‐one Derivatives.
Authors: Murineddu Gabriele , Cignarella Giorgio , Chelucci Giorgio , Loriga Giovanni , Pinna Gerard Aime
Published: May 2010

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Reactivity of Stable Trifluoroacetaldehyde Hemiaminals. Part 3. Generation and Use of an Equivalent of Difluoroacetamide or Difluoroacetate Anions.
Authors: Blond Gaelle , Billard Thierry , Langlois Bernard R.
Published: May 2010

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A σ4,λ5‐Phosphinine Palladium Complex: A New Type of Phosphorus Ligand and Catalyst. Application to the Pd‐Catalyzed Formation of Arylboronic Esters.
Authors: Doux Marjolaine , Mezailles Nicolas , Melaimi Mohand , Ricard Louis , Le Floch Pascal
Published: May 2010

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Intramolecular Radical Hydrosilylation — The First Radical 5‐Endo‐dig Cyclization.
Authors: Amrein Stephan , Studer Armido
Published: May 2010

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Synthesis of α‐Aminophosphonates under Conditions of Phase‐Transfer Catalysis.
Authors: Kabachnik M. M. , Ternovskaya T. N. , Zobnina E. V. , Beletskaya I. P.
Published: May 2010

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1,2‐Diaza‐1,3‐butadienes: A New Approach to the Synthesis of Selenoheterocycles.
Authors: Attanasi Orazio A. , Filippone Paolino , Perrulli Francesca R. , Santeusanio Stefania
Published: May 2010

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Novel Selective Acid‐Catalyzed Rearrangement of the Carane‐Type α‐(N‐Acylamino)oximes: The X‐Ray Structure of (1S,5S)‐1‐Isopropyl‐3,5‐dimethyl‐2‐oxa‐4‐azabicyclo [3.3.1]non‐3‐en‐6‐one (E)‐Oxime.
Authors: Agafontsev Alexander M. , Rybalova Tatyana V. , Gatilov Yury V. , Tkachev Alexey V.
Published: May 2010

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Stereoselective Catalytic Hydrogenation of Δ7‐6‐Ketosteroids in the Presence of Sodium Nitrite.
Authors: Suksamrarn Apichart , Tanachatchairatana Tanud , Sirigarn Chana
Published: May 2010

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Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities.
Authors: Zhao Jing , Nakamura Norio , Hattori Masao , Kuboyama Tomoharu , Tohda Chihiro , Komatsu Katsuko
Published: May 2010

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Chloroperoxidase‐Catalyzed Oxidation of Methionine Derivatives.
Authors: Holland Herbert L. , Brown Frances M. , Lozada Damian , Mayne Benjamin , Szerminski W. Rick , van Vliet Aaron J.
Published: May 2010

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Enhancement of Magneto‐Optical Effects in Magnetite Nanocrystals Near Gold Surfaces.
Authors: Shemer Gabriel , Markovich Gil
Published: May 2010

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Oxidation‐Resistant Gold‐55 Clusters.
Authors: Boyen H.‐G. , et al. et al.
Published: May 2010

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[Ge9=Ge9=Ge9]6‐: A Linear Trimer of 27 Germanium Atoms.
Authors: Ugrinov Angel , Sevov Slavi C.
Published: May 2010

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Enantioselective 1,3‐Dipolar Cycloaddition of Nitrones Catalyzed by Optically Active Cationic Cobalt(III) Complexes.
Authors: Mita Tsuyoshi , Ohtsuki Natsuki , Ikeno Taketo , Yamada Tohru
Published: May 2010

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3,6‐Bis(triphenylphosphonium)cyclohexene Peroxodisulfate as an Efficient and Mild Oxidizing Agent for Conversion of Alkylbenzenes to Corresponding Carbonyl Compounds.
Authors: Badri Rashid , Soleymani Mousa
Published: May 2010

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Reaction of Allylzinc Reagents and Zinc Enolates of Ketones with α‐Amidoalkylphenyl Sulfones.
Authors: Petrini Marino , Profeta Roberto , Righi Paolo
Published: May 2010

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Synthesis of Highly Functionalized Arene Systems. Novel Selectivities of Intra‐ and Intermolecular Friedel—Crafts Reactions.
Authors: McMills Mark C. , Wright Dennis L. , Weekly R. Matt
Published: May 2010

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Z‐Selective Synthesis of α,β‐Unsaturated Amides with Triphenylsilylacetamides.
Authors: Kojima Satoshi , Inai Hiroki , Hidaka Tsugihiko , Fukuzaki Tomohide , Ohkata Katsuo
Published: May 2010

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Pinacolboratamethylenetriphenylphosphonium Iodide, a New Methylene Transfer Reagent.
Authors: Quntar Abed Al‐Aziz , Srebnik Morris
Published: May 2010

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The Prenyl Group: A Versatile Hydroxy Protecting Group, Removable Chemoselectively under Mild Conditions.
Authors: Vatele Jean‐Michel
Published: May 2010

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Bismuth Nitrate‐Mediated Deprotection of Oximes.
Authors: Samajdar Susanta , Basu Manas K. , Becker Frederick F. , Banik Bimal K.
Published: May 2010

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Synthesis of (E)‐ and (Z)‐29‐Methylidyne‐2,3‐oxidosqualene Derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase.
Authors: Ceruti Maurizio , Viola Franca , Balliano Gianni , Milla Paola , Roma Giorgio , Grossi Giancarlo , Rocco Flavio
Published: May 2010

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New Synthesis of α‐Benzylaldehydes from 2‐(Dimethylphenylsilylmethylene)alkanals by Fluoride Promoted Phenyl Migration.
Authors: Aronica Laura Antonella , Morini Francesca , Caporusso Anna Maria , Salvadori Piero
Published: May 2010

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New Protocol for the Catalytic Pauson—Khand Reaction Induced by Molecular Sieves.
Authors: Blanco‐Urgoiti Jaime , Casarrubios Luis , Dominguez Gema , Perez‐Castells Javier
Published: May 2010

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Reactivities of Novel [Hydroxy(tosyloxy)iodo]arenes and [Hydroxy(phosphoryloxy)iodo]arenes for α‐Tosyloxylation and α‐Phosphoryloxylation of Ketones.
Authors: Nabana Takahiro , Togo Hideo
Published: May 2010

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A New Route for Generation of .alpha±lambda.3‐Iodanyl Ketones via Ester Exchange of (Z)‐(β‐Acetoxyvinyl)‐λ3‐iodanes: Their Nucleophilic Substitutions with Halides and Sulfur and Phosphorus Nucleophiles.
Authors: Ochiai Masahito , Nishitani Junichi , Nishi Yoshio
Published: May 2010

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Chemistry of Dicationic Electrophiles: Superacid‐Catalyzed Reactions of Amino Acetals.
Authors: Klumpp Douglas A. , Sanchez Jr. Gregorio V. , Aguirre Sharon L. , Zhang Yun , de Leon Sarah
Published: May 2010

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Nucleophilic Substitution on 4‐Hydroxymethylanilines under “Neutral” Conditions via Aza Quinone Methide Intermediate.
Authors: Takahashi Hiroyasu , Kashiwa Nobuyuki , Kobayashi Hisayoshi , Hashimoto Yuichi , Nagasawa Kazuo
Published: May 2010

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Stereoselective Construction of Functionalized (Z)‐Fluoroalkenes Directed to Depsipeptide Isosteres.
Authors: Okada Midori , Nakamura Yuko , Saito Akio , Sato Azusa , Horikawa Hiroaki , Taguchi Takeo
Published: May 2010

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[1,3] Sigmatropic Rearrangement of Ketene Silyl Acetals Derived from Benzyl α‐Substituted Propanoates.
Authors: Shiina Isamu , Nagasue Hiroshi
Published: May 2010

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Unexpected Side Reactions of Imidazolium‐Based Ionic Liquids in the Base‐Catalyzed Baylis—Hillman Reaction.
Authors: Aggarwal Varinder K. , Emme Ingo , Mereu Andrea
Published: May 2010

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Nickel/Zinc‐Mediated Synthesis of Aromatic Nitriles from Aromatic Oxime Ethers.
Authors: Maeyama Katsuya , Kobayashi Masato , Kato Hiroshi , Yonezawa Noriyuki
Published: May 2010

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Dimerization of Acetylenic Amides.
Authors: Usifoh Cyril O. , Okunrobo Lucky O.
Published: May 2010

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Synthesis of 2‐Indanones via [4 + 1] Annulation Reactions of (Trialkylsilyl)arylketenes.
Authors: Dalton Audra M. , Zhang Yongjun , Davie Christopher P. , Danheiser Rick L.
Published: May 2010

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Intramolecular Cycloadditions of α‐Allyloxycarbonylnitrones: Stereoselective Synthesis of 3‐Amino‐2(5H)furanones.
Authors: Chiacchio Ugo , Corsaro Antonio , Iannazzo Daniela , Piperno Anna , Procopio Antonio , Rescifina Antonio , Romeo Giovanni , Romeo Roberto
Published: May 2010

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Studies on Synthesis of 3(2H)‐Benzofuranone Derivatives.
Authors: Bokotey Sandor , Kovari‐Radkai Maria , Podanyi Benjamin , Ritz Imola , Hanusz Miklos , Batori Sandor
Published: May 2010

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Friedel—Crafts Acylation of Indoles in Acidic Imidazolium Chloroaluminate Ionic Liquid at Room Temperature.
Authors: Yeung Kap‐Sun , Farkas Michelle E. , Qiu Zhilei , Yang Zhong
Published: May 2010

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Study of the Reactions of Four Indolic 1‐Azadienes with a Few Enoic, Ynoic, and Azo Dienophiles.
Authors: Chakrabarty Manas , Sarkar Sandipan , Khasnobis Shampa , Harigaya Yoshihiro , Sato Noriko , Arima Shiho
Published: May 2010

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Fluorinated Ketene Dithioacetals. Part 9. Synthesis and Some Chemical Properties of New Fluorinated 3H‐1,2‐Dithiole‐3‐thiones.
Authors: Timoshenko Vadim M. , Bouillon Jean‐Philippe , Shermolovich Yuriy G. , Portella Charles
Published: May 2010

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The Application of Vinylogous Iminium Salt Derivatives to the Regiocontrolled Preparation of Heterocyclic Appended Pyrazoles.
Authors: Gupton John T. , et al. et al.
Published: May 2010

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4‐Functionally Substituted 3‐Heterylpyrazoles. Part 8. 3‐Aryl(heteryl)‐4‐hydroxy(chloro)methylpyrazoles.
Authors: Bratenko M. K. , Chornous V. A. , Vovk M. V.
Published: May 2010

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A Simple and Efficient Method for the Synthesis of Novel Trifluoromethyl Benzimidazoles under Microwave Irradiation Conditions.
Authors: Reddy G. Venkat , Rao V. V. V. N. S. Rama , Narsaiah B. , Rao P. Shanthan
Published: May 2010

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Efficient and General Synthesis of 5‐(Alkoxycarbonyl)methylene‐3‐oxazolines by Palladium‐Catalyzed Oxidative Carbonylation of Prop‐2‐ynylamides.
Authors: Bacchi Alessia , Costa Mirco , Gabriele Bartolo , Pelizzi Giancarlo , Salerno Giuseppe
Published: May 2010

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New Bis‐aminomercaptotriazoles and Bis‐Triazolothiadiazoles as Possible Anticancer Agents.
Authors: Holla B. Shivarama , Poojary K. Narayana , Rao B. Sooryanarayana , Shivananda M. K.
Published: May 2010

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Photocatalyzed [2 + 2 + 2]‐Cycloaddition of Nitriles with Acetylene: An Effective Method for the Synthesis of 2‐Pyridines under Mild Conditions.
Authors: Heller Barbara , Sundermann Bernd , Buschmann Helmut , Drexler Hans‐Joachim , You Jingsong , Holzgrabe Ulrike , Heller Eberhard , Oehme Guenther
Published: May 2010

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Synthesis of Tetrasubstituted Pyridines by the Acid‐Catalyzed Bohlmann—Rahtz Reaction.
Authors: Bagley Mark C. , Brace Christian , Dale James W. , Ohnesorge Maren , Phillips Nathan G. , Xiong Xin , Bower Justin
Published: May 2010

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Stereoselective Synthesis of 1,2‐ and 1,4‐Dihydropyridines by Using Cation‐π Interaction as a Conformation‐Controlling Tool.
Authors: Yamada Shinji , Saitoh Momoe , Misono Tomoko
Published: May 2010

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Syntheses of Allyldihydroquinolines: Indium‐Mediated Allylations of EEDQ in the Presence of Acetic Acid.
Authors: Lee Ji Hee , Kweon Jin Sun , Yoon Cheol Min
Published: May 2010

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One‐Pot Synthesis of Tetrahydroquinolines Catalyzed by Dy(OTf)3 in Aqueous Solution.
Authors: Chen Ruifang , Qian Changtao
Published: May 2010

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Vasorelaxing Properties of Some Phenylacridine Type Potassium Channel Openers in Isolated Rabbit Thoracic Arteries.
Authors: Berkan Oecal , Sarac Buelent , Simsek Rahime , Yildirim Sahin , Sarioglu Yusuf , Safak Cihat
Published: May 2010

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Reduction of Imidazo[4,5‐c]pyridine and [1,2,3]Triazolo[4,5‐c]pyridine Derivatives to Spinaceamines and 2‐Azaspinaceamines.
Authors: Yutilov Yu. M. , Smolyar N. N. , Astashkina N. V.
Published: May 2010

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An Exceedingly Mild and Efficient Synthesis of 1,2,4‐Triazolo[4,3‐a][1,8]naphthyridines Using Iodobenzene Diacetate in the Solid State.
Authors: Mogilaiah K. , Babu H. Ramesh , Reddy N. Vasudeva
Published: May 2010

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Microwave‐Assisted Synthesis of Aminopyrimidines.
Authors: Luo Guanglin , Chen Ling , Poindexter Graham S.
Published: May 2010

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Synthesis and Evaluation for Biological Activity of 3‐Alkyl and 3‐Halogenoalkyl‐quinoxalin‐2‐ones Variously Substituted. Part 4.
Authors: Carta Antonio , Sanna Paolo , Loriga Mario , Setzu Maria Giovanna , La Colla Paolo , Loddo Roberta
Published: May 2010

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Synthesis of Variously 9,9‐Dialkylated Octahydropyrimido[3,4‐a]‐s‐triazines with Potential Antifungal Activity.
Authors: Ghaib Amar , Menager Sabine , Verite Philippe , Lafont Olivier
Published: May 2010

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Studies in Large Ring Compounds: Synthesis of Some New Morphanthridines and Diazocines.
Authors: Pawar V. G. , Bhusare S. R. , Pawar R. P. , Bhawal B. M.
Published: May 2010

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Chemoenzymatic Syntheses of Polyamines and Tetraazamacrocycles.
Authors: Rubio Mercedes , Astorga Covadonga , Alfonso Ignacio , Rebolledo Francisca , Gotor Vicente
Published: May 2010

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DTBB‐Catalyzed Lithiation of 4‐Hetero‐Substituted Dibenzothiins.
Authors: Yus Miguel , Foubelo Francisco , Ferrandez Jose V.
Published: May 2010

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Unprecedented 1,3‐Dipolar Cycloaddition of Azomethine Ylides to Ester Carbonyl.
Authors: Novikov Mikhail S. , Voznyi Igor V. , Khlebnikov Alexander F. , Kopf Juergen , Kostikov Rafael R.
Published: May 2010

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Indium‐Mediated Allylation Reaction of Difluoroacetyltrialkylsilanes in Aqueous Media.
Authors: Chung Woo Jin , Higashiya Seiichiro , Welch John T.
Published: May 2010

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t‐BuOK‐Catalyzed Addition Phosphines to Functionalized Alkenes: A Convenient Synthesis of Polyfunctional Phosphine Derivatives.
Authors: Bunlaksananusorn Tanasri , Knochel Paul
Published: May 2010

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Modification of A and B Rings in 20‐Dihydroisoxazolyl Steroids and Their Derivatives with a Functionalized Side Chain.
Authors: Litvinovskaya R. P. , Koval' N. V. , Khripach V. A.
Published: May 2010

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Structural Revision of Halipeptins: Synthesis of the Thiazoline Unit and Isolation of Halipeptin C.
Authors: Della Monica Carmela , Randazzo Antonio , Bifulco Giuseppe , Cimino Paola , Aquino Maurizio , Izzo Irene , De Riccardis Francesco , Gomez‐Paloma Luigi
Published: May 2010

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Carbohydrate Carbocyclization by a Zinc‐Mediated Tandem Reaction and Ring‐Closing Enyne Metathesis.
Authors: Poulsen Carina Storm , Madsen Robert
Published: May 2010

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Synthesis of α‐ and β‐Glycosyl Asparagine Ethylene Isosteres (C‐Glycosyl Asparagines) via Sugar Acetylenes and Garner Aldehyde Coupling.
Authors: Dondoni Alessandro , Mariotti Giandomenico , Marra Alberto
Published: May 2010

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Construction of Carbohydrate‐Based Antitumor Vaccines: Synthesis of Glycosyl Amino Acids by Olefin Cross‐Metathesis.
Authors: Biswas Kaustav , Coltart Don M. , Danishefsky Samuel J.
Published: May 2010

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Nitrone Dipolar Cycloaddition Routes to Piperidines and Indolizidines. Part 9. Formal Synthesis of (‐)‐Pinidine and Total Synthesis of (‐)‐Histrionicotoxin, (+)‐Histrionicotoxin and (‐)‐Histrionicotoxin 235A.
Authors: Holmes Andrew B. , et al. et al.
Published: May 2010

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Reactions of Indole and Its Derivatives with Cotarnine. Rearrangement of 5‐(1‐Indolyl)‐4‐methoxy‐6‐methyl‐5,6,7,8‐tetrahydro[1,3]dioxolo [4,5‐g]isoquinolines.
Authors: Krasnov K. A. , Kartsev V. G.
Published: May 2010

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Synthesis of 1‐(3′,6′‐Anhydro‐2′‐deoxy‐β‐D‐glucofuranosyl)thymine.
Authors: Mereyala Hari Babu , Pola Pallavi
Published: May 2010

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Studies on the Synthesis of (‐)‐Spinosyn A: Application of the Steric Directing Group Strategy to Transannular Diels—Alder Reactions.
Authors: Frank Scott A. , Roush William R.
Published: May 2010

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Studies Towards the Total Synthesis of Solanoeclepin A: Synthesis and Potato Cyst Nematode Hatching Activity of Analogues Containing the Tetracyclic Left‐Hand Substructure.
Authors: Benningshof Jorg C. J. , IJsselstijn Maarten , Wallner Sabine R. , Koster Anne L. , Blaauw Richard H. , van Ginkel Angeline E. , Briere Jean‐Francois , van Maarseveen Jan H. , Rutjes Floris P. J. T. , Hiemstra Henk
Published: May 2010

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Synthesis of Taurospongin A: A Potent Inhibitor of DNA Polymerase and HIV Reverse Transcriptase, Using π‐Allyltricarbonyliron Lactone complexes.
Authors: Hollowood Christopher J. , Ley Steven V. , Yamanoi Shigeo
Published: May 2010

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A Calorimetric and Statistical Mechanics Study of Water Adsorption in Zeolite NaY.
Authors: Boddenberg B. , Rakhmatkariev G. U. , Hufnagel S. , Salimov Z.
Published: May 2010

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Trititanate Nanotubes Made via a Single Alkali Treatment.
Authors: Chen Qing , Zhou Wuzong , Du Gaohui , Peng Lian‐Mao
Published: May 2010

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Magnetic Coupling Between Liquid 3He and Solid Insulators
Authors: Naletov V. V. , Tagirov M. S. , Tayurski D. A.
Published: May 2010

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Towards the Rational Design of Zeolite Frameworks
Authors: Wagner Paul , Davis Mark E.
Published: May 2010

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Complexes Containing Metal—Carbon σ‐Bonds of the Groups Titanium to Manganese, Including Carbenes and Carbynes. Part 2. Group 5
Authors: Page Elizabeth M.
Published: May 2010

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Scandium, Yttrium and the Lanthanoids
Authors: Brennan John G. , Sella Andrea
Published: May 2010

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Group 2 (Be—Ba) and Group 12 (Zn—Hg)
Authors: Layfield Richard A. , Wright Dominic S.
Published: May 2010

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Chemistry of Bicyclic Pyridines Containing a Ring‐Junction Nitrogen
Authors: Hamama W. S. , Zoorob H. H.
Published: May 2010

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Recent Advancements in the Homoallylamine Chemistry.
Authors: Puentes Cristian Ochoa , Kouznetsov Vladimir
Published: May 2010

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Leukotriene Modifiers: Novel Therapeutic Opportunities in Asthma
Authors: Buccellati Carola , Fumagalli Francesca , Viappiani Serena , Folco Giancarlo
Published: May 2010

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The Medicinal Chemistry of Multidrug Resistance (MDR) Reversing Drugs.
Authors: Teodori E. , Dei S. , Scapecchi S. , Gualtieri F.
Published: May 2010

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Polyhedral Monocarbaborane Chemistry. A Review of Recent Developments Among C‐Aryl Monocarbaborane Systems.
Authors: Franken Andreas , Kilner Colin A. , Thornton‐Pett Mark , Kennedy John D.
Published: May 2010

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Muonium — The Second Radioisotope of Hydrogen — and Its Contribution to Free Radical Chemistry
Authors: Rhodes Christopher J.
Published: May 2010

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Synthesis of 2′‐O‐Alkylnucleosides
Authors: Zatsepin T. S. , Romanova E. A. , Oretskaya T. S.
Published: May 2010

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Foundation of the Bases for Protein Research and Its Application to the Pharmaceutical Science Field
Authors: Imoto Taiji
Published: May 2010

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Aziridines: Epoxides′ Ugly Cousins?
Authors: Sweeney J. B.
Published: May 2010

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Catalytic Asymmetric Synthesis with Chiral Ligands Bearing Organosulfur Functionality
Authors: Hiroi Kunio
Published: May 2010

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Synthetic Studies for the Novel Morpholine‐ and Oxazolidine‐Based Tachykinin Receptor Antagonists
Authors: Nishi Takahide
Published: May 2010

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Asymmetric Automultiplication of Chiral Compounds by Asymmetric Autocatalysis
Authors: Soai Kenso , Sato Itaru , Shibata Takanori
Published: May 2010

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Enthalpic and Entropic Contributions to the Conformational Free Energy Differences in Monosubstituted Cyclohexanes
Authors: Juaristi Eusebio , Munoz‐Muniz Omar
Published: May 2010

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Histaminic H3‐Receptors and Pharmacological Regulation of Their Function
Authors: Spasov A. A. , Chernikov M. V.
Published: May 2010

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Biological and Medical Significance of Calcium Phosphates.
Authors: Dorozhkin Sergey V. , Epple Matthias
Published: May 2010

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The Scientific and Human Legacy of Max Perutz (1914—2002).
Authors: Thomas John Meurig
Published: May 2010

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Biomineralization in Diatoms Mediated Through Peptide‐ and Polyamine‐Assisted Condensation of Silica.
Authors: Pohnert Georg
Published: May 2010

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Chemical Reactivity as Described by Quantum Chemical Methods
Authors: Geerlings P. , De Proft F.
Published: May 2010

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Hybrid QM/MM Car—Parrinello Simulations of Catalytic and Enzymatic Reactions
Authors: Colombo Maria Carola , Guidoni Leonardo , Laio Alessandro , Magistrato Alessandra , Maurer Patrick , Piana Stefano , Rohrig Ute , Spiegel Katrin , Sulpizi Marialore , VandeVondele Joost , et al. et al.
Published: May 2010

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Template‐Synthesized Nanotubes for Chemical Separations and Analysis.
Authors: Wirtz Marc , Parker Matthew , Kobayashi Yoshio , Martin Charles R.
Published: May 2010

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Identification and Mapping of Small‐Molecule Binding Sites in Proteins: Computational Tools for Structure‐Based Drug Design.
Authors: Sotriffer Christoph , Klebe Gerhard
Published: May 2010

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Sulfur Compounds. Part 224. Tetraamidosulfurane and Its Decomposition Products — An ab initio MO Study.
Authors: Steudel Ralf , Steudel Yana , Lentz Dieter
Published: May 2010

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Synthesis and Characterization of Ru‐Doped n = 1 and n = 2 Ruddlesden—Popper Manganates.
Authors: Gallon Daniel J. , Battle Peter D. , Blundell Stephen J. , Burley Jonathan C. , Coldea Amalia I. , Cussen Edmund J. , Rosseinsky Matthew J. , Steer Christopher
Published: May 2010

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Mechanism of Dihydrogen Formation in the Magnesium—Water Reaction.
Authors: Taub Irwin A. , Roberts Warren , LaGambina Sebastian , Kustin Kenneth
Published: May 2010

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Synthesis, Crystal Structure, and Spectroscopic Characterization of the Phosphorane Iminato Complexes [Cl2BNPCl2NPCl3]2 and [Br2BNPCl3]2.
Authors: Jaeschke Britta , Jansen Martin
Published: May 2010

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Ca3(BN2)N, The Missing Compound in the Quasi Binary Ca3N2—BN System.
Authors: Haeberlen Marco , Glaser Jochen , Meyer H.‐Juergen
Published: May 2010

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A Solid State Metathesis Route for the Synthesis of Lanthanum Nitridoborates.
Authors: Jing Haipeng , Blaschkowski Bjoern , Meyer H.‐Juergen
Published: May 2010

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Synthesis, Crystal Structure, and Oxide Ion Conductivity in Bi4.6Ca1.1VO10.5.
Authors: Radosavljevic Evans Ivana , Tao Shanwen , Irvine John T. S. , Howard Judith A. K.
Published: May 2010

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Synthesis and Characterization of a New Ferrimagnetic Mixed‐Valent Iron Fluorophosphate [C6N4H21] [FeIII3‐xFeIIxF2 (PO4)(HPO4)2]2 (x ≈ 1.5) with a Layered Structure.
Authors: Mandal Sukhendu , Natarajan Srinivasan , Greneche Jean Marc , Riou‐Cavellec Myriam , Ferey Gerard
Published: May 2010

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Chemical and Structural Properties of a Whitlockite‐Like Phosphate, Ca9FeD(PO4)7.
Authors: Belik A. A. , Izumi F. , Stefanovich S. Yu. , Lazoryak B. I. , Oikawa K.
Published: May 2010

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Asymmetric Nucleophilic Addition Reactions of Aldehydes with Optically Active Dithioacetals and Their Application to Optically Active α‐Hydroxy Ketone Synthesis.
Authors: Taka Hideo , Fujita Ken‐ichi , Oishi Akihiro , Taguchi Yoichi
Published: May 2010

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Stereoselective Functionalization of Dithiolanes and Dithianes: The First Example of an Axial Trapping.
Authors: Capperucci Antonella , Cere Vanda , Degl'Innocenti Alessandro , Nocentini Tiziano , Pollicino Salvatore
Published: May 2010

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Remarkably High 1,5‐Diastereoselectivity in a Nickel‐Catalyzed Conjugate Addition of Me2Zn and Carbonyl Compounds to 1,ω‐Dienynes with Through‐Space Coupling.
Authors: Ezoe Akihiro , Kimura Masanari , Inoue Takahiro , Mori Masahiko , Tamaru Yoshinao
Published: May 2010

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Synthesis of Substituted Naphthalenes by the Palladium‐Catalyzed Annulation of Internal Alkynes.
Authors: Huang Qinhua , Larock Richard C.
Published: May 2010

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Sulfinyl‐Mediated Chirality Transfer in Diastereoselective Claisen Rearrangements.
Authors: Fernandez de la Pradilla Roberto , Montero Carlos , Tortosa Mariola
Published: May 2010

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The Rupe Rearrangement: A New Efficient Method for Large‐Scale Synthesis of Unsaturated Ketones in the Pilot Plant.
Authors: Weinmann Hilmar , Harre Michael , Neh Harribert , Nickisch Klaus , Skoetsch Carlo , Tilstam Ulf
Published: May 2010

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W(CO)5‐Amine Catalyzed exo‐ and endo‐Selective Cyclizations of ω‐Alkynyl Silyl Enol Ethers: A Highly Useful Method for the Construction of Polycyclic Compounds.
Authors: Kusama Hiroyuki , Yamabe Hokuto , Iwasawa Nobuharu
Published: May 2010

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Gif Chemistry for Oxidation of Activated Methylenes to Ketones.
Authors: Kim Sung Soo , Sar Santosh Kumar , Tamrakar Pankaj
Published: May 2010

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Catalytical Oxidation of Propylene and Isobutylene on Multicomponent Molybdenum Containing Contacts
Authors: Loura B. B.
Published: May 2010

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A Simple and Efficient Iodination of Alcohols on Polymer‐Supported Triphenylphosphine.
Authors: Anilkumar Gopinathan , Nambu Hisanori , Kita Yasuyuki
Published: May 2010

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Sonogashira Coupling with Aqueous Ammonia.
Authors: Mori Atsunori , Ahmed Mohamed S. Mohamed , Sekiguchi Akitoshi , Masui Kentaro , Koike Tooru
Published: May 2010

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Preferential Hydrolysis of Benzylic/Allylic Dithianes and Dithiolanes Using o‐Iodoxybenzoic Acid (IBX) in DMSO Containing Traces of Water.
Authors: Wu Yikang , Shen Xin , Huang Jia‐Hui , Tang Chao‐Jun , Liu He‐Hua , Hu Qi
Published: May 2010

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Rearrangement Reactions. Part 12. Synthesis and Reactions of Isothiocyanate Substituted Allenes.
Authors: Banert Klaus , Groth Stefan , Hueckstaedt Holger , Lehmann Jens , Schlott Jana , Vrobel Kai
Published: May 2010

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Facile Synthesis of [5.n.1.01,5] Tricycles Mediated by Intramolecular Pauson—Khand Reaction of 3‐Alkynyl‐1‐alkylidenecyclic Compounds.
Authors: Ishizaki Miyuki , Masamoto Mina , Hoshino Osamu
Published: May 2010

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LiClO4—Acyl Anhydrides Complexes as Powerful Acylating Reagents of Aromatic Compounds in Solvent‐Free Conditions.
Authors: Bartoli Giuseppe , Bosco Marcella , Marcantoni Enrico , Massaccesi Massimo , Rinaldi Samuele , Sambri Letizia
Published: May 2010

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An Efficient and Cost‐Effective Synthesis of 3‐Ethoxy‐4‐ethoxycarbonyl‐phenylacetic Acid: A Key Acid Synthon of Repaglinide (VI).
Authors: Salman Mohammad , Babu Suresh J. , Ray Purna C. , Biswas Sujoy , Kumar Naresh
Published: May 2010

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Synthesis and Microbiological Activity of Some N‐(2‐Hydroxy‐4‐substitutedphenyl)benzamides, Phenylacetamides and Furamides as the Possible Metabolites of Antimicrobial Active Benzoxazoles.
Authors: Aki‐Sener Esin , Bingoel Kamuran K. , Temiz‐Arpaci Oezlem , Yalcin Ismail , Altanlar Nurten
Published: May 2010

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Palladium‐Catalyzed Homocoupling Reactions Between Two Csp3—Csp3 Centers.
Authors: Lei Aiwen , Zhang Xumu
Published: May 2010

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A Convenient Method for the Synthesis of 4,4‐Diarylbut‐1‐enes via the Successive Allylation of Aromatic Aldehydes and the Friedel—Crafts Alkylation Reaction of Aromatic Nucleophiles with the Intermediary Benzyl Silyl Ethers Using HfCl4 or Cl2Si(OTf)2.
Authors: Shiina Isamu , Suzuki Masahiko , Yokoyama Kazutoshi
Published: May 2010

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Asymmetric Epoxidation of Aldehydes Catalyzed by New C2‐Symmetrical Chiral Sulfide.
Authors: Ishizaki Miyuki , Hoshino Osamu
Published: May 2010

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Epoxidation of Olefins by Cobalt‐Containing Polyoxotungstate and Potassium Monopersulfate in Aqueous Solution.
Authors: Choi Sun Kyung , Lee Ha Jin , Kim Hyungrok , Nam Wonwoo
Published: May 2010

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Deiodination of Iodolactones by Transfer Hydrogenolysis Using Raney Nickel and 2‐Propanol.
Authors: Mebane Robert C. , Grimes Kimberly D. , Jenkins Summer R. , Deardorff Jonathan D. , Gross Benjamin H.
Published: May 2010

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Synthesis of 3‐Aminopyrrolidines by Cyclization of Neutral C‐Centered α‐Aminoalkyl Radicals.
Authors: Suero Ruben , Gorgojo Jose M. , Aurrecoechea Jose M.
Published: May 2010

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A Direct Lithiation Route to 2‐Acyl‐1‐(phenylsulfonyl)indoles.
Authors: Jiang Jun , Gribble Gordon W.
Published: May 2010

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Synthesis of 3‐(N‐Alkylaminomethyl)carbazoles Containing Functional Groups at the Alkyl Part of the Molecule
Authors: Alekseeva N. V. , Bokanov A. I. , Alekseeva L. M. , Granik V. G.
Published: May 2010

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Diastereoselective Ultrasonically Induced Zinc—Copper Conjugate Addition to Chiral α,β‐Unsaturated Carbonyl Systems in Aqueous Media.
Authors: Suarez Rosa Ma. , Sestelo Jose Perez , Sarandeses Luis A.
Published: May 2010

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Synthesis and Electrochemical Studies of Tetrathiafulvalene Derivatives (TTF′S) as Redox Active Ligands.
Authors: Sarhan Abd El‐Wareth A. O. , Murakami Makoto , Izumi Taeko
Published: May 2010

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[Ir4(CO)12]‐Catalyzed Coupling Reaction of Imidazoles with Aldehydes in the Presence of a Hydrosilane to Give 2‐Substituted Imidazoles.
Authors: Fukumoto Yoshiya , Sawada Katsutoshi , Hagihara Motoyuki , Chatani Naoto , Murai Shinji
Published: May 2010

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Regioselective Symmetrical Bromination of Protected 2,2′‐Diimidazole.
Authors: Sanchez‐Garcia David , Borros Salvador , Nonell Santi , Borrell Jose I. , Colominas Carles , Teixido Jordi
Published: May 2010

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2‐(2‐Hydroxy‐3‐alkoxyphenyl)‐1H‐benzimidazole‐5‐carboxamidine Derivatives as Potent and Selective Urokinase‐Type Plasminogen Activator Inhibitors.
Authors: Mackman Richard L. , et al. et al.
Published: May 2010

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Microwave Assisted Synthesis of New Benzimidazoles.
Authors: Njoya Yves , Boufatah Narimene , Gellis Armand , Rathelot Pascal , Crozet Michel P. , Vanelle Patrice
Published: May 2010

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Synthesis of Chiral Oxazolidin‐2‐ones by 1,2‐Amino Alcohols, Carbon Dioxide and Electrogenerated Acetonitrile Anion.
Authors: Feroci Marta , Gennaro Armando , Inesi Achille , Orsini Monica , Palombi Laura
Published: May 2010

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Indium Trifluoromethanesulfonate as a Mild and Chemoselective Catalyst for the Conversion of Carbonyl Compounds into 1,3‐Oxathiolanes.
Authors: Kazahaya Kiyoshi , Hamada Nao , Ito Shinya , Sato Tsuneo
Published: May 2010

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