bluuebunny/crossref_metadata_2025 huggingface dataset:
The Trapping by Nitric Oxide of Initially‐Formed Free Radicals in Photochemical Reactions: 1. The mercury‐6(3P1)‐photosensitized decomposition of propane and the deuterated propanes
Authors: Woodall George N. C. , Gunning Harry E.
Published: September 2010

A study has been made of the relative primary yields of n‐propyl and i‐propyl radicals in the reactions of Hg 6(3P1) atoms with C3H8, C3D8, CH3CD2CH3 and CD3CH2CD3. A fast flow system was used, at 25°, and a pressure of 11–12 mm, with (i) pure NO and (ii) a mixture of NO and 1‐C4H8, added as inhibitors.

With pure NO, the propyl radicals formed the corresponding oximes, nitropropanes, nitrites and nitrates. Low flow rates and low % (NO) favoured oxime formation. From the products, the relative percentage of those of n‐propyl origin (%(n‐pr)) could be determined. With pure NO, %(n‐pr) rose to a maximum with %(NO) in the 15–30 range. The high NO levels were required to scavenge primary H‐atoms. The same effect could be achieved by using 2% NO, and 4.8% 1‐butene. This dual‐inhibitor method gave the following results with the %(n‐pr) values in parentheses : C3H8(42); C3D8(49); CH3CD2CH3C77); CD3CH2CD3(25).

It is shown that the results can be explained in terms of a cyclic quenching complex involving quasi‐bivalent bonding of Hg 6(3P1) simultaneously to a primary and secondary CH (or CD) bond. The C3H8 and C3D8 cyclic complexes symmetrically cleave forming nearly equal yields of the two propyl radicals. With CH and CD bonds in the complex, as in CH3CD2CH8 and CD3CH2CD3, a D/H isotope effect of ca three results, favouring CH cleavage.
Sur la Réaction Photochimique des Composés Polyaromatiques Avec le Tétrachlorure de Carbone
Authors: Ivanoff Melle N.
Published: September 2010

Nous avons étudié les réactions photochimiques du tétrachlorure de carbone avec différents composés aromatiques polycycliques Benz‐1,2 Anthracène, Pyrène, Chrysène, trans‐Stilbène, et Naphtacène. Les rendements quantiques ont été mesurés dans chaque cas.

Pour toutes les substances étudiées, excepté le Naphtacène, l'échelle des réactivités trouvées est voisine de celle prévue pour une réaction d'addition des composés polyaromatiques à l'état fondamental. La réactivité du naphtacène est beaucoup plus faible que prévue. Son rendement quantique dépend de la température pour la longueur d'onde de 4360 Å.
Photochemical Reactions of Nitrophenylesters and ‐Ethers
Authors: Havinga E. , De Jongh R. O.
Published: September 2010

Several years ago we reported the occurrence of an intriguing type of photochemical reaction that was observed during illumination of solutions in water of nitrophenylphosphates and ‐sulphates and of nitrophenylethers (e.g. nitroanisoles) (1,2). In this communication some results of continued studies of these reactions are discussed.
Sur les Réactions Photochimiques de L'Acridine dans des Solvants Hydrogénés
Authors: Kellmann Melle A.
Published: September 2010

Nous avons étudié les réactions photochimiques de l'acridine dans divers solvants hydrogénés, par irradiation à 3.660 A. Le rendement quantique Φ (‐A) de la disparition de l'acridine a été mesuré dans chaque cas.

Les énergies de liaison C‐H dans les solvants utilisés ne sont pas seules responsables des rendements quantiques observés; des problèmes d'empêchement stérique interviennent également.
Photoréduction des Colorants Thiaziniques par les Acides Amino Polycarboxyliques Application aux Dosages de Mélanges de Cations
Authors: Joussot‐Dubien Jacques , Faure Jean
Published: September 2010

Nous avons étudié la photoréduction de la thionine et du bleu de méthylène par différents acides aminopolycarboxyliques (complexons) en solution.

1. La vitesse de photoréduction de la thionine passe par une valeur maximale entre pH 6 et 9 suivant la nature du complexon.

2. La vitesse de photoréduction du bleu de méthylène croit constamment avec le pH, mais semble tendre vers une vitesse maximale en milieu très basique, zone que l'on ne peut explorer puisque ce colorant se décompose à partir de pH 12.

Ces résultats peuvent s'expliquer si l'on admet que l'espèce chimique photosensible dans la solution est une association moléculaire entre une molécule de colorant, sous la forme acide la plus facilement réductible, et une molécule de complexon sous sa forme basique la plus facilement oxydable.

Nous avons exploité ces resultats en analyse complexométrique en dosant un melange Fer(III) — Aluminium.
La Sensibilisation Chimique du Bromure D'Argent
Authors: Hautot A.
Published: September 2010

La sensibilisation des émulsions de halogénures d'argent consiste en l'activation photochimique du halogénure traité par des traces de composés sulfurants, réducteurs ou de divers métaux nobles. Deux interprétations de cette activation ont été avancées : l'une admet que le sensibilisateur, en réagissant avec le halogène libéré pendant l'exposition lumineuse, évite la recombinaison du halogène avec l'argent photolytique; l'autre postule que le sensibilisateur crée, à la surface des cristaux du halogénure d'argent, des germes susceptibles de servir comme centres de condensation de l'argent photolytique. Les deux théories sont confrontées et discutées.
Internally Protected Amino Sugar Equivalents from Enantiopure 1,2‐Oxazines: Synthesis of Variably Configured Carbohydrates with C‐Branched Amino Sugar Units
Authors: Pfrengle Fabian , Reissig Hans‐Ulrich
Published: September 2010

A stereodivergent synthesis of differently configured C2‐branched 4‐amino sugar derivatives was accomplished. The Lewis acid mediated rearrangement of phenylthio‐substituted 1,2‐oxazines delivered glycosyl donor equivalents that can directly be employed in glycosidation reactions. Treatment with methanol provided internally protected amino sugar equivalents that have been transformed into the stereoisomeric methyl glycosides 28, ent‐28, 29, ent‐29 and 34 in two simple reductive steps. Reaction with natural carbohydrates or bicyclic amino sugar precursors allowed the synthesis of homo‐oligomeric di‐ and trisaccharides 44, 46 and 47 or a hybrid trisaccharide 51 with natural carbohydrates. Access to a bivalent amino sugar derivative 54 was accomplished by reaction of rearrangement product 10 with 1,5‐pentanediol. Alternatively, when a protected L‐serine derivative was employed as glycosyl acceptor, the glycosylated amino acid 60 was efficiently prepared in few steps. In this report we describe the synthesis of unusual amino sugar building blocks from enantiopure 1,2‐oxazines that can be attached to natural carbohydrates or natural product aglycons to produce new natural product analogues with potential applications in medicinal chemistry.
ChemInform Abstract: Imma Perovskite‐Type Oxynitride LaTiO2N: Structure and Electron Density.
Authors: Yashima Masatomo , Saito Mio , Nakano Hiromi , Takata Tsuyoshi , Ogisu Kiyonori , Domen Kazunari
Published: September 2010

A highly crystalline and high‐purity LaTiO2N sample is synthesized from the corresponding oxides by ammonolysis (1.
ChemInform Abstract: Photoluminescence and Concentration Quenching of NaCa4(BO3)3:Eu3+ Phosphor.
Authors: Zhang Xinmin , Seo Hyo Jin
Published: September 2010

The new title phosphor is synthesized by solid state reaction of Na2CO3, CaCO3, Eu2O3, and excess H3BO3 (880 °C, 12 h).
ChemInform Abstract: Magnetic Structure of ErCu2Ge2.
Authors: Penc B. , Baran S. , Kaczorowski D. , Hoser A. , Szytula A.
Published: September 2010

The title compound is characterized by neutron powder diffraction between 1.4 and 12.0 K and heat capacity measurements.
ChemInform Abstract: Phase Equilibria in the Oxide System Nd2O3—K2O—P2O5.
Authors: Szczygiel Irena , Znamierowska Teresa , Mizer Dagmara
Published: September 2010

The title system is studied with focus on the NdPO4—K3PO4—KPO3 partial system and the phase diagram of this region is constructed.
ChemInform Abstract: Structure and Stability of Sodium Intercalated Phases in Olivine FePO4.
Authors: Moreau P. , Guyomard D. , Gaubicher J. , Boucher F.
Published: September 2010

Two new NaxFePO4 (x = 0.7, 1) phases with olivine‐based structures are electrochemically synthesized using a mixture of FePO4 and carbon black as positive electrode, Na as negative electrode, and NaClO4 solution as electrolyte.
ChemInform Abstract: A Ferromagnetic Carbodiimide: Cr2(NCN)3.
Authors: Tang Xiaojuan , Xiang Hongping , Liu Xiaohui , Speldrich Manfred , Dronskowski Richard
Published: September 2010

The title compound, the first transition‐metal(III) carbodiimide with a 3d3 configuration is prepared from a mixture of CrCl3 and ZnNCN using LiCl/KCl as a flux (550 °C, 2 d).
ChemInform Abstract: Topochemical Synthesis of Europium Molybdenum Oxynitride Pyrochlores.
Authors: Yang Minghui , Oro‐Sole Judith , Fuertes Amparo , Attfield J. Paul
Published: September 2010

Eu2Mo2O7 (I) is synthesized from a stoichiometric mixture of Eu2O3, MoO2, and Mo (alumina boat, flowing Ar, 1450 °C, 14 h) and EuMoO4 (II) from a stoichiometric mixture of Eu2O3, MoO3, and Mo (quartz tube, 600 °C, 24 h, and 1050 °C, 36 h).
ChemInform Abstract: Combined Magnetic Susceptibility Measurements and 57Fe Moessbauer Spectroscopy on a Ferromagnetic {Fe4IIIDy4} Ring.
Authors: Schray Dirk , Abbas Ghulam , Lan Yanhua , Mereacre Valeriu , Sundt Alexander , Dreiser Jan , Waldmann Oliver , Kostakis George E. , Anson Christopher E. , Powell Annie K.
Published: September 2010

The new compound (III) crystallizes in the monoclinic space group P21/n with Z = 4.
ChemInform Abstract: Two Novel Copper—Undecaniobates Decorated by Copper—Organic Cations [{Cu(H2O) L}2{CuNb11O35H4}]5‐ (L: 10‐Phenanthroline, 2,2′‐Bipyridine) Consisting of Plenary and Monolacunary Lindqvist‐Type Isopolyniobate Fragments.
Authors: Niu Jing‐Yang , Chen Guo , Zhao Jun‐Wei , Ma Peng‐Tao , Li Su‐Zhi , Wang Jing‐Ping , Li Ming‐Xue , Bai Yan , Ji Bian‐Sheng
Published: September 2010

Compounds (III) and (IV) represent the first examples of copper undecaniobates.
ChemInform Abstract: Actinide Tetracyanoplatinates: Synthesis and Structural Characterization with Uncharacteristic Th—NC Coordination and Thorium Fluorescence.
Authors: Maynard Branson A. , Sykora Richard E. , Mague Joel T. , Gordon Anne E. V.
Published: September 2010

The structures of the new tetracyanoplatinates (III) (monoclinic, space group C2/c, Z = 4), (IV) (orthorhombic, Pbca, Z = 8), and (VI) (tetragonal, P4/mbm, Z = 4) are determined by single crystal.
ChemInform Abstract: One‐Pot System for Reduction of Epoxides Using NaBH4, PdCl2 Catalyst, and Moist Alumina.
Authors: Yakabe Shigetaka
Published: September 2010

Aryl epoxides are smoothly reduced and give exclusively the least substituted alcohols.
ChemInform Abstract: Highly Efficient Diastereoselective Reduction of α‐Fluoroimines.
Authors: Malamakal Roy M. , Hess Whitney R. , Davis Todd A.
Published: September 2010

The new methodology for the reduction of α‐fluoroimines is based on the ability of fluorine and nitrogen to activate organosilanes which results in enhanced reducing reactivity and high diastereoselectivity.
ChemInform Abstract: N,N′‐Dioxide—Cu(OTf)2 Complex Catalyzed Highly Enantioselective Amination Reaction of N‐Acetyl Enamide.
Authors: Chang Lu , Kuang Yulong , Qin Bo , Zhou Xin , Liu Xiaohua , Lin Lili , Feng Xiaoming
Published: September 2010

The title reaction performs well over a range of substituted α‐aromatic N‐acetyl enamides.
ChemInform Abstract: Efficient Pd‐Catalyzed Coupling of Tautomerizable Heterocycles with Terminal Alkynes via C—OH Bond Activation Using PyBrOP.
Authors: Shi Ce , Aldrich Courtney C.
Published: September 2010

The alkynylation of tautomerizable heterocycles is described via a two step process involving in situ C—OH activation with PyBroP followed by Sonagashira coupling with a range of alkynes.
ChemInform Abstract: A Facile Demethylation of ortho Substituted Aryl Methyl Ethers Promoted by AlCl3.
Authors: Du Zhen‐Ting , Lu Jing , Yu Hong‐Rui , Xu Yan , Li An‐Pai
Published: September 2010

Aryl methyl ethers which are ortho‐substituted with electron‐withdrawing groups are selectively demethylated in the presence of aluminum chloride.
ChemInform Abstract: A Copper(II)‐Mediated Regioselective Cyclization—Acetoxylation of 6,8‐Dien‐1‐ones for the Synthesis of Functionalized Cyclopentanes.
Authors: Wang Yazhou , Du Haifeng
Published: September 2010

In the presence of Cu(O‐Ac)2 and NaOAc, 6,8‐dien‐1‐ones undergo regio‐ and stereoselective cyclization—acetoxylation.
ChemInform Abstract: Benzylic Bromination of Toluene Derivatives with Boron Tribromide.
Authors: Chen Hongbiao , Shen Litao , Lin Yuanbin
Published: September 2010

The presented method avoids the formation of dibrominated products.
ChemInform Abstract: Oxidation and Deprotection of Primary Benzylamines by Visible Light Flavin Photocatalysis.
Authors: Lechner Robert , Koenig Burkhard
Published: September 2010

The oxidation of a variety of benzylamines and structurally related compounds is investigated.
ChemInform Abstract: Reductive Amination Using Ammonia Borane.
Authors: Ramachandran P. Veeraraghavan , Gagare Pravin D. , Sakavuyi Kaumba , Clark Paul
Published: September 2010

The reaction of aldehydes and ketones with primary and secondary amines under conditions A) and B) affords secondary and tertiary amine products in excellent yields.
ChemInform Abstract: 4‐Hydroxy‐2′‐nitrodiphenyl Ether Analogues as Novel Tyrosinase Inhibitors.
Authors: Sapkota Kiran , Lee Eunyoung , Yang Jae‐Ho , Kwon Youngjoo , Choi Jongwon , Na Younghwa
Published: September 2010

A series of hydroxy‐ and nitro‐substituted diphenyl ethers are prepared as novel tyrosinase inhibitors.
ChemInform Abstract: Synthesis of Substituted N‐[3‐(3‐Methoxyphenyl)propyl] Amides as Highly Potent MT2‐Selective Melatonin Ligands.
Authors: Hu Yueqing , Ho Maurice K. C. , Chan King H. , New David C. , Wong Yung H.
Published: September 2010

The title compounds (I) are screened for their binding affinities towards human melatonin MT1 and MT2 receptors.
ChemInform Abstract: Direct Metal‐Free α‐Iodination of Arylketones Induced by Iodine or Iodomethane with HTIB in Ionic Liquid.
Authors: Lee Jong Chan , Kim Jimi , Park Hyun Jung , Kwag Byungmook , Lee Seung Bae
Published: September 2010

PhI(OH)‐O‐Tos (HTIB) is shown to promote the α‐iodination of ketones in [bmim]BF4.
ChemInform Abstract: Synthesis of Unsymmetrical o‐Biphenols and o‐Binaphthols via Silicon‐Tethered Pd‐Catalyzed C—H Arylation.
Authors: Huang Chunhui , Gevorgyan Vladimir
Published: September 2010

A practical and efficient synthesis of unsymmetrical o‐biphenol derivatives is presented.
ChemInform Abstract: Facile and Green Method for the Synthesis of β‐Aminoketone Derivatives in Aqueous Media.
Authors: Wang Xiang‐Shan , Zhou Jie , Yang Ke , Li Qing
Published: September 2010

The three‐component reaction has the advantage of operational simplicity and green solvent.
ChemInform Abstract: Short Synthesis of COX‐2 Inhibitor Inotilone.
Authors: Al‐Busafi Saleh , Al‐Belushi Muna , Al‐Muqbali Khalid
Published: September 2010

The title compound (VI) is prepared from commercially available acetaldoxime (I) by using isoxazole chemistry.
ChemInform Abstract: Diastereoselective Synthesis of Tetrahydrofurans from Aryl 3‐Chloropropylsulfoxides and Aldehydes.
Authors: Komsta Zofia , Barbasiewicz Michal , Makosza Mieczyslaw
Published: September 2010

Sulfoxides of type (I) smoothly react with electron‐rich nonenolizable aldehydes to afford trans‐substituted tetrahydrofurans with high stereoselectivity.
ChemInform Abstract: Regioselective Synthesis of 3‐Indolyl(alkoxy)acetates.
Authors: Suarez‐Castillo Oscar R. , Melendez‐Rodriguez Myriam , Cano‐Escudero Indira C. , Luz De Ita‐Gutierrez Sandra , Sanchez‐Zavala Maricruz , Morales‐Rios Martha S. , Joseph‐Nathan Pedro
Published: September 2010

(Z)‐ and (E)‐2‐alkoxyindolenines (V) and (VI) are synthesized by treating bromoindole (II) with alcohols in the presence of molecular sieves.
ChemInform Abstract: Copper‐Mediated Cyclization—Halogenation and Cyclization—Cyanation Reactions of β‐Hydroxyalkynes and o‐Alkynylphenols and Anilines.
Authors: Swamy Nalivela Kumara , Yazici Arife , Pyne Stephen G.
Published: September 2010

The reactions allow a new and direct access to functionalized furopyrroles, benzofurans, and indoles.
ChemInform Abstract: Synthesis, Spectral and Antimicrobial Studies of Some N(2)‐Substituted Tetrahydroindazoles.
Authors: Amirthaganesan Shanmugasundaram , Aridoss Gopalakrishnan , Park Keun Soo , Lim Kwon Taek , Jeong Yeon Tae
Published: September 2010

2 series of 9 title compounds each of type (III) and (IV) are prepared and tested for their antimicrobial activities.
ChemInform Abstract: Imidazo[1,2]hetarylglyoxylates: Synthesis and Reactivity Toward Nucleophiles.
Authors: Zamkova Irina A. , Chekotylo Oleksiy O. , Geraschenko Oleksandr V. , Grygorenko Oleksandr O. , Mykhailiuk Pavel K. , Tolmachev Andrey A.
Published: September 2010

The title compounds are synthesized via Friedel—Crafts acylation of fused imidazoles with ethyl oxalyl chloride.
ChemInform Abstract: Construction of Linked Nitrogen Heterocycles by Palladium(0)‐Catalyzed Intramolecular Domino Cyclization of 2‐Alkynylaziridines Bearing a 2‐Aminoethyl Group via Ring Expansion with Isocyanate.
Authors: Okano Akinori , Oishi Shinya , Tanaka Tetsuaki , Fujii Nobutaka , Ohno Hiroaki
Published: September 2010

The Pd‐catalyzed reaction of alkynylaziridines of type (I) and (V) with isocyanates provides a new approach to pyrrolinylimidazolidinones and/or imidazolidinyldiazepinones depending on the nature of substituents and conditions used.
ChemInform Abstract: Exploration of Amino Alcohol Derivatives as Novel, Potent, and Highly Selective Sphingosine‐1‐phosphate Receptor Subtype‐1 Agonists.
Authors: Evindar Ghotas , et al. et al.
Published: September 2010

PPI‐4955 ((R)‐I) is found to be a potent and selective preclinical candidate with an excellent in vivo potency and dose responsiveness and markedly improved overall in vivo pharmacodynamic properties upon oral administration.
ChemInform Abstract: Synthesis of Benzoxazole Amides as Novel Antifungal Agents Against Malassezia furfur.
Authors: Kim Beom Joon , Kim Jinah , Kim Young‐Kook , Choi Soon‐Yong , Choo Hea‐Young Park
Published: September 2010

A series of 12 benzoxazole amides (VI) are prepared and tested as antifungal agents against Malassezia furfur.
ChemInform Abstract: Synthesis of Perfluorinated Heterocyclic Compounds Having a Long Alkyl Chain Functionality by 1,3‐Dipolar Cycloaddition.
Authors: Lee Chan Woo , Hwang Ho Yun , Park Joo Yuen , Chi Ki‐Whan
Published: September 2010

Perfluorinated compounds having a long alkyl‐chain functionality are prepared by 1,3‐dipolar cycloaddition reactions with 1,3‐dipoles (in situ‐formed NH‐nitrones or nitrile oxides).
ChemInform Abstract: Synthesis of 2,6‐Bis(fluoroalkyl) ‐2,6‐dihydroxytetrahydro‐2H‐pyran‐3,5‐dicarboxylates from Aldehydes and Fluorinated β‐Oxo Esters in the Presence of Ionic Liquid—K2CO3 as Catalytic System.
Authors: Zlotin S. G. , Kryshtal G. V. , Zhdankina G. M. , Ignatenko A. V. , Burgart Ya. V. , Saloutin V. I. , Chupakhin O. N.
Published: September 2010

The catalytic system retains its catalytic activity for three reaction cycles.
ChemInform Abstract: Facile Synthesis of 9‐Acetyl/Formyl/Cyano‐substituted Pyrano[2,3‐f]flavones and Chromones Using the Baylis—Hillman Reaction.
Authors: Reddy S. Satyanarayana , Krupadanam G. L. David
Published: September 2010

Novel flavones / chromones (III) with a pyran ring fused at 7,8‐position are synthesized starting from the corresponding 8‐formyl‐7‐hydroxy derivatives via Baylis‐Hillman reaction.
ChemInform Abstract: Synthesis and Reactions of Some Novel Nicotinonitrile, Thiazolotriazole, and Imidazolotriazole Derivatives for Antioxidant Evaluation.
Authors: Sayed Hayam H. , Morsy Eman M. H. , Flefel Eman M.
Published: September 2010

Novel 2‐O‐substituted pyridine derivatives are synthesized and tested for their free radical scavenging capacity in DPPH assay.
ChemInform Abstract: A One‐Step Synthesis of 2,4‐Unsubstituted Quinoline‐3‐carboxylic Acid Esters from o‐Nitrobenzaldehydes.
Authors: Venkatesan Hariharan , Hocutt Frances M. , Jones Todd K. , Rabinowitz Michael H.
Published: September 2010

The methodology uses commercially available esters (II) and (V), is operationally simple and tolerates a broad spectrum of functionalities.
ChemInform Abstract: Simple and Efficient Synthesis of 2‐Aryl‐2,3‐dihydroquinolin‐4(1H)‐ones Using Silica Chloride as a New Catalyst under Solvent‐Free Conditions.
Authors: Muthukrishnan M. , Mujahid M. , Punitharasu V. , Dnyaneshwar D. A.
Published: September 2010

Title compounds (II) are also obtained from a similar one‐pot reaction between 2‐aminoacetophenone and aromatic aldehydes, but yields are only poor.
ChemInform Abstract: Amberlite IRA 402(OH): An Efficient Mediator for the Exclusive Synthesis of Fused Tricyclic Oxaza Quinolinium Salts.
Authors: Paira Rupankar , Paira Priyankar , Maity Arindam , Mondal Shyamal , Hazra Abhijit , Sahu Krishnendu B. , Naskar Subhendu , Saha Pritam , Banerjee Maitreyee , Mondal Nirup B.
Published: September 2010

The improved protocol for the preparation of the biologically interesting title compounds uses the Amberlite resin instead of phase transfer catalysts.
ChemInform Abstract: Triethylamine Promoted Efficient Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones/thiones Using a Solvent‐Free Biginelli Condensation.
Authors: Debache Abdelmadjid , Ghalem Wassima , Boulcina Raouf , Belfaitah Ali , Rhouati Salah , Carboni Bertrand
Published: September 2010

An efficient and environmentally benign protocol for the synthesis of 3,4‐dihydropyrimidin‐2(1H)‐ones and ‐thiones (IV) is described.
ChemInform Abstract: Synthesis, Reactions, and Antimicrobial Evaluation of Some Polycondensed Thienopyrimidine Derivatives.
Authors: Rashad Aymn E. , Shamroukh Ahmed H. , Abdel‐Megeid Randa E. , El‐Sayed Wael A.
Published: September 2010

A variety of novel polycondensed thienopyrimidine derivatives are synthesized starting from 2‐aminoindenothiophene‐3‐carboxylic amide (I).
ChemInform Abstract: Synthesis of 2,3‐Dihydroquinazoline‐4(1H)‐ones.
Authors: Shaterian Hamid Reza , Oveisi Ali Reza , Honarmand Moones
Published: September 2010

A practical method for the synthesis of the title compounds via three‐component reaction of isatoic anhydride (I) with aromatic aldehydes and primary amines or ammonium salts under solvent‐free conditions is developed.
ChemInform Abstract: (S)‐3‐(4‐(2‐(5‐Methyl‐2‐phenyloxazol‐4‐yl)ethoxy)phenyl)‐2‐ (piperazin‐1‐yl)‐propanoic Acid Compounds: Synthesis and Biological Evaluation of Dual PPARα/γ Agonists.
Authors: Zhou Xinbo , Chen Wei , Xu Cheng , Fan Shiyong , Xie Yunde , Zhong Wu , Wang Lili , Li Song
Published: September 2010

A series of novel piperazinylpropanoic acid derivatives (I) are designed, synthesized and evaluated as dual PPARα/γ agonists.
ChemInform Abstract: Stereoselective Synthesis of Tetrasubstituted Alkenylboronates via 1,1‐Organodiboronates.
Authors: Endo Kohei , Hirokami Munenao , Shibata Takanori
Published: September 2010

A facile and stereoselective method to prepare (E)‐tetrasubstituted target compounds as versatile building blocks is presented.
ChemInform Abstract: Synthesis of [1‐(Dimethylamino)alkyl]phosphonates from (1‐Hydroxyalkyl)phosphonates: Transformation of Allylic Hydroxyphosphonates into Allylic Aminophosphonates.
Authors: Kaboudin Babak , Faghihi Mohammad Reza
Published: September 2010

The transformation of substrates (I) succeeds without any catalyst to give the synthetically important novel title compounds (III) in moderate to good yield.
ChemInform Abstract: Synthesis, Spectral Characterization and Antimicrobial Activity of Novel 5‐[(Substituted)methyl] ‐5‐oxo‐1,3,2λ4,5λ 5‐dioxaselenaphosphinan‐2‐ones.
Authors: Reddy S. Subba , Krishna B. Satheesh , Rao V. Koteswara , Raju C. Naga
Published: September 2010

Title compounds (IV) are synthesized starting from tris(bromomethyl)phosphine oxide (I).
ChemInform Abstract: A New Cytotoxic Tambjamine Alkaloid from the Azorean Nudibranch Tambja ceutae.
Authors: Gavagin Margherita , et al. et al.
Published: September 2010

Tambjamine K (I) displays high cytotoxicity against both tumor and non‐tumor mammalian cells.
ChemInform Abstract: N‐Aryltriazole Ribonucleosides with Potent Antiproliferative Activity Against Drug‐Resistant Pancreatic Cancer.
Authors: Liu Yang , Xia Yi , Fan Yuting , Maggiani Alain , Rocchi Palma , Qu Fanqi , Iovanna Juan L. , Peng Ling
Published: September 2010

A variety of novel N‐aryltriazole nucleosides is synthesized via Cu‐mediated C—N cross‐coupling of 3‐aminotriazole ribonucleoside and various aromatic boronic acids.
ChemInform Abstract: Stereoselective Divergent Synthesis of Four Diastereomers of Pachastrissamine (Jaspine B).
Authors: Yoshimitsu Yuji , Inuki Shinsuke , Oishi Shinya , Fujii Nobutaka , Ohno Hiroaki
Published: September 2010

Pachastrissamine (Ia) and its epimers (Ib) and (II) are prepared to investigate structure—activity relationships.
ChemInform Abstract: Expedient Synthesis, on Large Scale, of Aliphatic Chaetomellic Anhydrides from N‐Allyl‐2,2‐dichlorocarboxyamides.
Authors: Ghelfi Franco , Pattarozzi Mariella , Roncaglia Fabrizio , Giangiordano Valerio , Parsons Andrew F.
Published: September 2010

The title method is suitable for large‐scale production of chaetomellic anhydride (VII).
ChemInform Abstract: Synthesis and Ligand Based 3D‐QSAR of 2,3‐Bis‐benzylidenesuccinaldehyde Derivatives as New Class Potent FPTase Inhibitor, and Prediction of Active Molecules.
Authors: Soung Min‐Gyu , Kim Jong‐Han , Kwon Byoung‐Mog , Sung Nack‐Do
Published: September 2010

A series of 29 title compounds of type (I) are prepared by a known procedure and tested as new FPTase inhibitors.
ChemInform Abstract: Magnetism of Complex Metallic Alloys: Crystalline Electric Field Effects
Authors: Bauer E. , Rotter M.
Published: September 2010

Review: 50 refs.
ChemInform Abstract: CaBr2 Hydrolysis for HBr Production Using a Direct Sparging Contactor
Authors: Yang Jianhong , Panchal C. B. , Doctor Richard D.
Published: September 2010

Review: 8 refs.
ChemInform Abstract: Synthesis of Metal Enolato Complexes
Authors: Vicente Jose
Published: September 2010

Review: 1102 refs.
ChemInform Abstract: Biological Importance of the Indole Nucleus in Recent Years: A Comprehensive Review
Authors: Sharma Vikas , Kumar Pradeep , Pathak Devender
Published: September 2010

Review: 37 refs.
ChemInform Abstract: The Synthesis and Physiological Activity of 2,3,4,5‐Tetrahydro‐1H‐pyrido[4,3‐b]indoles
Authors: Ivachtchenko A. V. , Mitkin O. D. , Kadieva M. G. , Tkachenko S. E.
Published: September 2010

Review: 146 refs.
ChemInform Abstract: Isolation, Structure Elucidation, and Asymmetric Synthesis of Biologically Active New Lycopodium Alkaloids
Authors: Takayama Hiromitsu
Published: September 2010

Review: ca. 50 refs.
ChemInform Abstract: Synthesis of Clarithromycin, a Macrolide Antibiotic and Development of the Next Generation Macrolides
Authors: Tanikawa Tetsuya , Kashimura Masato
Published: September 2010

Review: ca. 50 refs.
ChemInform Abstract: MicroAntibodies: Directed Evolution of Molecular Targeting Peptides in Phage‐Displayed Libraries of Conformationally Constrained Peptides
Authors: Fujii Ikuo
Published: September 2010

Review: 16 refs.
ChemInform Abstract: O‐Phosphotyrosine Analogues: Synthesis and Therapeutic Role in Modulation of Signal Transduction
Authors: Wardle Nick J. , Hudson Harry R. , Bligh S. W. Annie
Published: September 2010

Review: 149 refs.
ChemInform Abstract: Recent Advances in Carbocupration of α‐Heterosubstituted Alkynes
Authors: Basheer Ahmad , Marek Ilan
Published: September 2010

Review: 72 refs.
ChemInform Abstract: Synthesis of Alkyl‐ and Cycloalkylamines by Substitution of Carbon Functionalities via Solvolysis
Authors: Montforts F.‐P. , Osmers M. , Azov V. A.
Published: September 2010

Review: 153 refs.
ChemInform Abstract: Hybrid Electronics and Electrochemistry with Conjugated Polymers
Authors: Inganaes Olle
Published: September 2010

Review: 130 refs.
ChemInform Abstract: Unraveling the Structure of the Ribosome (Nobel Lecture)
Authors: Ramakrishnan V.
Published: September 2010

Review: 104 refs.
ChemInform Abstract: Multidimensional Potential of Boron‐Containing Molecules in Functional Materials
Authors: Kaim Wolfgang , Hosmane Narayan S.
Published: September 2010

Review: 117 refs.
ChemInform Abstract: SPring‐8 Structural Biology Beamline
Authors: Kumasaka Takashi , Shimizu Nobutaka , Baba Seiki , Hasegawa Kazuya , Ueno Go , Yamamoto Masaki
Published: September 2010

Review: 13 refs.
Three‐phase fluidized distillation
Authors: Ravagnani Teresa M.K. , Pereira João A.F.R.
Published: September 2010

Separation efficiency in distillation operations can be improved by modifying the characteristics of the dispersions formed on the trays. The present work reports on the hydrodynamic and mass transfer characteristics of liquid‐solid‐vapour dispersions formed on sieve trays without downcomers of a distillation column operating under total reflux conditions. Murphree efficiency and the operating limits of distillation using the ethanol‐n‐butanol system are analyzed for a large range of vapour velocities and liquid mixture compositions, utilising wettable PVC particles and non‐wettable silicone, PE, and Teflonr̀ particles. It was verified that wettable particles show a drastic reduction in the upper operating limit of vapour velocity, but this does not occur for non‐wettable particles. Tray efficiency can be increased when non‐wettable particles are used, mainly for high vapour velocity operations.
Solubility of sulphur dioxide in mixed polyethylene glycol dimethyl ethers
Authors: Schmidt Kurt A.G. , Mather Alan E.
Published: September 2010

The solubility of sulphur dioxide in mixed polyethylene glycol dimethyl ethers was determined at 25°C, 40°C, 70°C and 100°C. The results were best correlated with the NRTL activity coefficient model. Henry's law constants were obtained from the data and the excess enthalpy of the liquid mixture over the full range of composition was predicted at each temperature. In addition, the enthalpy of mixing and the enthalpy of solution were both determined at infinite dilution. The effect of water on the solubility of sulphur dioxide was also investigated with a 6.04 mass% water solution.
Modelling the continuous drying of a thin sheet of fibres on a cylinder heated by electric induction
Authors: Pérez Sergio , Thérien Normand , Broadbent Arthur Douglass
Published: September 2010

The derived model predicts the evolution of the humidity and temperature of a thin web of fibrous material during drying on the surface of a metal cylinder heated by electric induction. The model explicitly considered heat conduction, convection and radiation, and thermal induction as well as energy transfer caused by the evaporation of the water. It also predicted the process responses to perturbations in the manipulated variables and in the initial humidity of the web entering a small‐scale induction dryer. The manipulated variables included the rotational speed of the cylinder, the electric power fed to the inductors, and the area of the web in contact with the cylinder. The simulations carried out showed a high degree of correspondence between the model predictions and the experimental data.
Uniform flux heat transfer in concentric laminar flow of two immiscible liquids
Authors: Stockman Gordon E. , Epstein Norman
Published: September 2010

The energy equation was solved exactly for fully developed steady laminar flow in a circular pipe of two immncible Newton liquids with a concentric cylindrical interface between them, assuming invariant physical properties of the liquids, uniform heat flux at the wall and fully developed temperature profiles. It is shown that, even if the viscosity of the annular liquid is orders of magnitude smaller than that of the core liquid, the improvement in heat transfer to the core liquid by infection of the annular liquid cannot exceed a factor of 1 8
The life and death of gc: The changeover to si and the declining use of gc in chemical engineering textbooks
Authors: Ruiz‐Beviá Francisco
Published: September 2010

Thirty years ago, an editorial on metrology in the March 1971 issue of AlChE Journal noted the following: “Recognizing the inevitable, the AlChE Journal will require that all papers submitted after July 1, 1971 conform in notation to the SI System (Système International d'Unités)”. This decision was the starting point for the gradual introduction of the use of the SI System in chemical engineering textbooks, at a substitute for the preceding British System. As a consequence, the use of the gc conversion factor has been also diminishing, gradually but at a slower pace In this paper, the changeover to SI and the declining use of gc in chemical engineering textbooks is analyzed. Firstly, some representative books published before 1971 are studied. Secondly, a special analysis is devoted to transport phenomena books. Finally, a few but significant books published since 1971, have been selected in order to carry out the analysis of the changeover to SI System and the evolution of the use of gc
Synthesis and Photophysics of Novel Soluble Polymeric Zn Metal Complex Based on Bis(8‐hydroxyquinoline) Groups with Benzene Unit
Authors: Huo Yanping , Zhu Shizheng
Published: September 2010

A novel ligand: 2,2′‐(1,3‐phenylenedivinylene)bis‐8‐hydroxyquinoline (m‐B8QPH) (4) and the corresponding polymeric metal complex Zn(m‐B8QPH) (5) were designed and synthesized in a convenient way. The luminescence properties of the compounds Zn(m‐B8QPH) (5) and Zn(p‐B8QPH) (9) were investigated by UV‐vis and fluorescence spectra in DMF at room temperature. The experimental results showed that the polymeric complexes 5 and 9 emitted yellow luminescence at 578 and 554 nm in DMF solution. The polymeric complex 5 has demonstrated good solubility in common organic solvents and good thermal stability with high Tg: 261°C. Furthermore, the molecular interactions of 5 with fullerene (C60) and fulleropyrrolidine containing 3,5‐bis(trifluoromethyl)benzene (11) were also investigated, which indicated the metal dye 5 can be used as new fluorescent probe.
Comparison of Sirolimus‐ and Paclitaxel‐Eluting Stents in Patients Undergoing Primary Percutaneous Coronary Intervention for ST‐Elevation Myocardial Infarction: A Meta‐analysis of Randomized Trials
Authors: Li Yong‐le , Wan Zheng , Lu Wen‐li , Wang Jian‐hua
Published: September 2010

Background

It has been reported that sirolimus‐eluting stents (SES) and paclitaxel‐eluting stents (PES) have been more effective than bare‐metal stents in reducing restenosis and cardiac events in a broad range of patients with coronary artery disease. However, it is unknown whether there might be differences between these two drug‐eluting stents in terms of efficacy and safety in the setting of acute ST‐segment elevation myocardial infarction (STEMI).

Hypothesis

The aim of the present study was to compare SES with PES in patients with acute STEMI undergoing primary percutaneous coronary intervention (PCI).

Methods

The published research was scanned by formal searches of electronic databases (PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials) from January 2001 to February 2010. Internet‐based sources of information on the results of clinical trials in cardiology were also searched.

Results

A total of 4 randomized trials were included in the present meta‐analysis, involving 1105 patients (550 in the SES group, 555 in the PES group). SES were significantly more effective in the reduction of angiographic binary (≥50%) restenosis (4.0% vs 9.6%, odds ratio 0.38, 95% confidence interval 0.19 to 0.74, P = 0.004) compared to PES. The differences between SES and PES were not statistically significant with respect to target vessel revascularization (TVR), stent thrombosis, cardiac death, and myocardial infarction.

Conclusions

SES are superior to PES in reducing the incidence of restenosis in patients undergoing primary PCI for STEMI, with nonsignificant differences in terms of TVR, cardiac death, myocardial infarction, and stent thrombosis. Copyright © 2010 Wiley Periodicals, Inc.

The authors have no funding, financial relationships, or conflicts of interest to disclose.
Thrombo‐Cardiology
Authors: Richard Conti C.
Published: September 2010

magnified image

As a medical student I, along with my classmates, learned the coagulation cascade. Later, in 1968 when I passed my internal medicine boards and was on my way to becoming a cardiologist, I thought that was the last I had to remember that complicated series of events and the drugs used to alter coagulation. Little did I know at that time how important coagulation and anti‐coagulation would become for cardiovascular patients. Copyright © 2010 Wiley Periodicals, Inc.
Cholinergic inputs to laryngeal motoneurons functionally identified in vivo in rat: A combined electrophysiological and microscopic study
Authors: Bautista Tara G. , Sun Qi‐Jian , Zhao Wen‐Jing , Pilowsky Paul M.
Published: September 2010

The intrinsic laryngeal muscles are differentially modulated during respiration as well as other states and behaviors such as hypocapnia and sleep. Previous anatomical and pharmacological studies indicate a role for acetylcholine at the level of the nucleus ambiguus in the modulation of laryngeal motoneuron (LMN) activity. The present study investigated the anatomical nature of cholinergic input to inspiratory‐ (ILM) and expiratory‐modulated (ELM) laryngeal motoneurons in the loose formation of the nucleus ambiguus. Using combined in vivo intracellular recording, dye filling, and immunohistochemistry, we demonstrate that LMNs identified in Sprague–Dawley rat receive several close appositions from vesicular acetylcholine transporter‐immunoreactive (VAChT‐ir) boutons. ELMs receive a significantly greater number of close appositions (mean ± standard deviation [SD]: 47 ± 11; n = 5) than ILMs (32 ± 9; n = 8; t‐test P < 0.05). For both LMN types, more close appositions were observed on the cell soma and proximal dendrites compared to distal dendrites (two‐way analysis of variance [ANOVA], P < 0.0001). Using fluorescence confocal microscopy, almost 90% of VAChT‐ir close appositions (n = 45 boutons on n = 4 ELMs) were colocalized with the synaptic marker synaptophysin. These results support a strong influence of cholinergic input on LMNs and may have implications in the differential modulation of laryngeal muscle activity. J. Comp. Neurol. 518:4903–4916, 2010. © 2010 Wiley‐Liss, Inc.
Enhancing P2P live streaming performance by balancing description distribution and available forwarding bandwidth in P2P streaming network
Authors: Lin Chow‐Sing
Published: September 2010

In a peer‐to‐peer (P2P) network, peers not only receive services from the network, but also contribute their own resources to the network. The abundant resources brought by P2P networks have stimulated the wide deployment of resource‐consuming multimedia streaming services over a P2P architecture. Allowing for the heterogeneity of peers in their upload and download bandwidth, most researches adopt the Multiple Description Coding (MDC) technique to enable differentiated streaming services. However, due to the lack of a global view of description availability, they tend to cause the skewed distribution of descriptions and lead to the under‐utilization of aggregated resources on P2P networks. In the paper, we propose a novel approach to balance the distribution of descriptions and available upload bandwidth in the P2P live streaming network. Based on the description distribution and available upload bandwidth, the proposed balancing scheme determines what descriptions a new peer should receive and their source peers such that better system scalability can be achieved. The simulation experiments indicate that our proposed balancing scheme can effectively reduce the server bandwidth consumption and rejection rate. Furthermore, abandoned peers can recover their lost descriptions mostly from the existing peers in the network instead of the server. Copyright © 2010 John Wiley & Sons, Ltd.
Towards disposable sensors for drug quality control: Dextromethorphan screen‐ printed electrodes
Authors: Khaled Elmorsy , Hassan H. N. A. , Mohamed Gehad G. , Seleim Aly Eldin A.
Published: September 2010

A simple, rapid, reliable, and reproducible method for mass production of disposable sensors using screen‐printing technology is described. Homemade printing has been characterized and optimized on the basis of effects of the modifier and plasticizers. The fabricated bi‐electrode potentiometric strip containing both working and reference electrode was used as dextromethorphan (DXM) sensor. The proposed sensors worked satisfactorily in the concentration range from 10−5 to 10−2 mol L−1 with detection limit reaching 6 × 10−6 mol L−1 and adequate shelf life of 8 months. DXM was determined in pharmaceutical formulations under batch and flow injection analysis (FIA) conditions with sampling output 120 h−1. Copyright © 2010 John Wiley & Sons, Ltd.
Novel antioxidants in food quality preservation and health promotion
Authors: Shahidi Fereidoon , Zhong Ying
Published: September 2010

Autoxidation in food and biological systems is responsible for a multitude of adverse effects and implications in human health as well as in food stability and preservation. Antioxidants play a major role in preventing or delaying autoxidation and have attracted much attention as food stabilizers, dietary supplements and natural health products. Both synthetic and natural antioxidants are widely used in food products and an ever increasing number of research papers have appeared in the recent literature on the discovery and application of natural antioxidants and their therapeutic use in inhibiting a myriad of diseases. However, some common synthetic antioxidants have also become controversial due to their potential adverse effects on health. This overview provides the latest developments about novel antioxidants, particularly phenolic derivatives, peptides/protein hydrolysates, phospholipids and polysaccharides, and their role in food quality preservation and human health promotion.
Synthesis and Post‐Resolution Modification of New Axially Chiral Ligands for Asymmetric Catalysis
Authors: Fleming William J. , Müller‐Bunz Helge , Guiry Patrick J.
Published: September 2010

The synthesis of four new members of the Quinazolinap series of ligands is described. Three of these ligands were prepared by post‐resolution modification of the known ligand (R)‐7‐chloro‐2‐isopropyl‐Quinazolinap, a new approach which offers an expedient route to a range of enantiopure ligands as it precludes the need for resolution of each ligand prepared. The remaining ligand, 7‐chloro‐2‐methyl‐Quinazolinap, was prepared in a seven‐step synthetic sequence incorporating palladium‐ and nickel‐catalyzed transformations as the key steps. A diastereomerically pure palladacycle of this ligand was characterised by X‐ray crystallography. (R)‐7‐Chloro‐2‐isopropyl‐Quinazolinap was applied to the rhodium‐catalyzed hydroboration of vinylarenes with regioselectivities of up to > 99:1 and ee values of up to 68 %. Each of the Quinazolinap ligands prepared were applied to the palladium‐catalyzed allylic alkylation of 1,3‐diphenylprop‐2‐enyl acetate resulting in conversions of up to 100 % and ee values of up to 85 %. Solution‐phase NMR studies on a palladium complex of one of the ligands provided a rationale for the sense of asymmetric induction.
A Combined Experimental and Theoretical Study of Anion–π Interactions in N6‐ and N9‐Decyladenine Salts (Eur. J. Org. Chem. 27/2010)
Authors: Garcia‐Raso Angel , Albertí Francisca M. , Fiol Juan J. , Lagos Yolanda , Torres Marta , Molins Elies , Mata Ignasi , Estarellas Carolina , Frontera Antonio , Quiñonero David , Deyà Pere M.
Published: September 2010

The cover picture shows the interesting anion–π/π–π/anion–π assembly that is found in the solid‐state architecture of an adenine derivative hydrochloride salt. The adenine has been decorated with a long alkyl chain (C10) in order to have a predefined ordering in the crystal due to hydrophobic effects. The influence of anion–π and π–π interactions on the final structure has been studied both experimentally and theoretically. Details are discussed in the article by A. Garcia‐Raso et al. on p. 5171 ff. The background picture depicts the scientific tradition of the Balearic Islands that springs from Ramon Llull, a 13th century philosopher, who founded a college in Miramar that is located in the northwest of the island of Majorca.
Hierarchical dynamic modeling of outbreaks of mountain pine beetle using partial differential equations
Authors: Zheng Yanbing , Aukema Brian H.
Published: September 2010

In this article, we develop spatial—temporal generalized linear mixed models for spatial—temporal binary data observed on a spatial lattice and repeatedly over discrete time points. To account for spatial and temporal dependence, we introduce a spatial—temporal random effect in the link function and model by a diffusion—convection dynamic model. We propose a Bayesian hierarchical model for statistical inference and devise Markov chain Monte Carlo algorithms for computation. We illustrate the methodology by an example of outbreaks of mountain pine beetle on the Chilcotin Plateau of British Columbia, Canada. We examine the effect of environmental factors while accounting for the potential spatial and temporal dependence. Copyright © 2010 John Wiley & Sons, Ltd.
On the voice‐data integration in third generation wireless access communication networks
Authors: Paterakis Michael , Cleary Allan C.
Published: September 2010

Mobile wireless communications, which includes cellular telephones, land mobile radio, and personal communication systems, have experienced enormous growth over the last decade. Data services represent a critical component of future wireless communications, but have received little attention. While some attention has been given to specialized mobile data networks, less has been directed at the ongoing design of data services in evolving digital cellular networks. In this paper we report on the results of a simulation study which explores voice‐data integration performance in third generation wireless communication networks. These networks are designed to provide access to broadband ISDN networks for large numbers of mobile voice and data users. The primary goal of the paper is the development of multiple access transmission protocols that will enable the voice and data terminals to efficiently share the terminal to base station wireless channel. Reservation Random Access (RRA) protocols are used for voice traffic, and multiple random access contention protocols are used for data traffic. The RRA protocols used enable the data terminals to precisely determine the end of voice packet contention periods, therefore providing a natural separation between voice and data contention. Such voice data integration mechanisms allow the voice contending terminals to resolve their contention without any interference from the data terminals. Data contention resolution does not degrade the voice performance, since it follows the voice contention resolution. The above approach is a promising alternative to other existing proposals due to its superior data packet throughput‐delay performance under steady state, and voice performance under transient conditions. Our results show that dispersed voice and data terminals can efficiently share a wireless channel.
Letter: Application of a simplified fano metric to adaptive receivers for digital mobile radio systems
Authors: Zimmermann Gerd , Rupprecht Werner
Published: September 2010

The detection list of sequential detection algorithms like the Generalized‐Stack‐Algorithm normally includes paths with different search lengths. Therefore, a special metric, the socalled Fano metric, has to be used to allow a comparison between the path metrics. A drawback of the Fano metric is its great computational effort in the case of a time‐variant channel impulse response which occurs typically at data transmission over frequency‐selective mobile radio channels. In this paper the most expensive part of the metric is replaced by a bias depending on the instantaneous signal‐to‐noise ratio and the phase characteristic of the channel. Simulation results obtained for the GSM system show the good performance of this method in view of bit error rate and computational complexity relative to the optimum Viterbi‐Algorithm.