bluuebunny/crossref_metadata_2025 huggingface dataset:
The Development and Implementation of a Culturally Safe Survey for Measuring Knowledge, Attitudes and Values around FASD and Alcohol Use During Pregnancy in a Remote Australian Aboriginal Community Setting
Authors:   Telethon Kids Institute, Symons Martyn , Tucker David ,   Telethon Kids Institute, Bruce Kaashifah ,   Telethon Kids Institute, Stearne Annalee ,   Curtin University, Kogolo Annette ,   Fitzroy Crossing, Carter Maureen ,   Fitzroy Crossing, Oscar June ,   Fitzroy Crossing, Pearson Glenn ,   Telethon Kids Institute, Fitzpatrick James ,   Telethon Kids Institute
Published: June 2022

Fetal Alcohol Spectrum Disorder (FASD) describes a lifelong neurodevelopmental disability caused by prenatal alcohol exposure that has a devastating impact on individuals, families and communities. The prevalence of FASD is high in some Indigenous communities around the World and the only active case ascertainment prevalence study conducted in Australia found a rate of 19.44 per 100 children in the remote Fitzroy Valley region of Western Australia. Following this study community led FASD prevention activities were implemented under the Marulu (“Worth Nurturing”) Strategy in the Fitzroy Valley. A Knowledge, Attitudes and Practices survey was designed to assess the impact of the prevention campaign and gather more information about knowledge of the dangers of alcohol use in pregnancy and FASD, local attitudes, and health behaviours both around alcohol and more generally including where residents received their health information. Best practices recommend including local Aboriginal people in the development of surveys and aiming to achieve cultural security. Actions taken included consulting with local health workers during survey development, translation of key sections of the survey into the local Kimberley Kriol, and performing the surveys with the assistance of Aboriginal Community Researchers. The full survey is made available in this paper. The surveys were conducted with 200 community members during August 2015 and 203 in October 2015. Surveys were updated between the first and second waves based on learnings during implementation. Key implementation details around weather and timing, gender/kinship issues, group participation, declining participation, problematic questions and responses to the survey are described. Cultural safety was achieved but further steps could be taken to ensure future cultural security by embedding cultural safety protocols in the survey and further community consultation.
Review of diabetes among Aboriginal and Torres Strait Islander people
Authors:   Edith Cowan University, Ride Katherine , Burrow Samantha ,   University of Western Australia
Published: June 2022

Diabetes is the fastest growing chronic disease condition globally. Type 2 diabetes in particular, has reached epidemic proportions, with the greatest burden falling on socially disadvantaged groups and Indigenous peoples. This review focuses primarily on type 2 diabetes among Aboriginal and Torres Strait Islander people, which is responsible for the majority of cases of diabetes in this population. It provides general information on the social and cultural context of diabetes, and the behavioural and biomedical factors that contribute to diabetes among Aboriginal and Torres Strait Islander people. This review provides detailed information on: the extent of diabetes among Aboriginal and Torres Strait Islander people, including incidence and prevalence data; hospitalisations; mortality and burden of disease the prevention and management of diabetes relevant programs, services, policies and strategies that address the health issue of diabetes among Aboriginal and Torres Strait Islander people two special population groups: adolescents pregnant and post-partum women. This review concludes by suggesting possible future directions for combatting the growing epidemic of diabetes among Aboriginal and Torres Strait Islander people. This review is part of a suite of knowledge exchange products that includes a summary, a video, and a fact sheet.
Mental Health of Clinical Nurses during the COVID-19 Pandemic in South Korea
Authors:   Crisis and Emergency Management: Theory and Praxis, Park Young Suk
Published: June 2022

Mental health of frontline nurses, who are critical healthcare personnel, is essential to overcome the COVID-19 pandemic. This study aimed to investigate the symptoms of depression, anxiety, perceived stress, and post-traumatic stress disorder of frontline nurses during the COVID-19 pandemic in South Korea. This was a cross-sectional online survey using the Patient Health Questionnaire, Generalized Anxiety Disorder, Perceived Stress Scale, and Impact of Event Scale-Revised from November 2020 to February 2021. The subjects were 249 nurses with work experience of at least one month at the frontline of the COVID-19 response. 39.4% of the participants had a higher than moderate level (≥10) of depression, 49.7% had a higher than mild level (≥5) of anxiety, and 40.1% were above the threshold of partial PTSD (≥18). The influencing factors of PTSD were depression, anxiety, COVID-19-related work period, and skipping meals, and their explanatory power was 60% (F=54.26, p<.001). Mental health of frontline nurses in clinical fields of COVID-19 screening/treatment need to be monitored and managed. In that regard, mental health programs and policies should be developed and legally guaranteed.
Insurance Transactions through Blockchain Applications: Current Status and Implications for the Domestic Insurance Industry
Authors:   Crisis and Emergency Management: Theory and Praxis, Kim Seonhyeon , Thompson Ephraim Kwashie , Kim Changki
Published: June 2022

This paper discusses the necessity for introducing blockchain technology into insurance sales channels. We focus on two factors that have hindered the sustainable development of the domestic insurance industry. The first problem is that insurance companies’ profitability is on the decline and the second issue relates to information asymmetry problems besetting insurance sales channels. The channels are heavily concentrated on general agencies (GA) but the GA channel has been characterized by problems such as incomplete sales and high termination rates. Due to the advantages of blockchain technology such as the transparency of information and reduction in transaction and security costs, insurance sales channels such as GA can help reduce insurance companies’ business costs and alleviate information asymmetry by adopting blockchain technology. Thus, in this paper, we discuss ways to utilize applications using blockchain platforms in insurance sales channels. This paper also introduces the web-based blockchain application of International Business Machines (IBM) and suggests that various stakeholders of insurance can interact through blockchain applications.
Causal Map of Fine Dust (PM10) Using System Dynamics: Focused on the Policy Variables in Seoul and Cheongju
Authors:   Crisis and Emergency Management: Theory and Praxis, Kim Kyu Ri , Lee Seung Hoon , Ban Yong Un
Published: June 2022

Fine dust was designated as a social disaster with top priority, a complex environmental problem, by the Ministry of Environment, Korea. in 2020. Policies to reduce fine dust from emission sources were differently implemented by city size. Previous research related to fine dust has dealt with both its impacts on health and its impacts on society as a whole. But, the studies did not consider changes in fine dust control factors, and did not employ dynamic analysis of policy factors according to city size. Therefore, this study intended to draw a causal loop of fine dust (PM10) emissions and effects using System Dynamics by city size considering policies. To reach this goal, this study has designed following research procedure: 1) to select factors that identify fine dust emission sources and the effects; 2) to investigate causal relationships between the causes and effects of fine dust; and 3) to draw a causal map of fine dust in consideration of policy variables by sectors by city hierarchy. As a result, the sources of fine dust included socioeconomic, demographic, and urban spatial variables, and the impacts of fine dust emissions due to differences in fine dust reduction policies by city size were identified in the causal map.
A Study on the Implementation of the Corporate Wage System in the Period of Employment Crisis
Authors:   Crisis and Emergency Management: Theory and Praxis, Koo Jung Mo
Published: June 2022

In this study, we tried to present practical implications of the effectiveness of the HR system through the research of the wage system of Korean companies in the period of employment crisis. Prior research related to the wage system were considered and team leader-level staff in charge of establishing/ improving/executing corporate HR policies were selected for research. And on-line surveys and in-depth interviews were conducted. It was confirmed that the wage system was treated as one of the HR system implemented but as an organizational and cultural factor optimized over a long period of time. It was also confirmed that the entity’s field needs for a level of practical research that can be used as a direct focus on the improvement and implementation of the current wage system. The results of this study led to the conclusion that securing its effectiveness through gradual application was the direction of implementation of the wage system in the period of employment crisis, considering that it was established over a long period of time under the influence of the labor market and organizational culture.
Authors:   Crisis and Emergency Management: Theory and Praxis, Jeong Kilho , Choi Changhui , Kim Changki
Published: June 2022

We attempt to analyze the VI (variable insurance) consumers’ behavior in Korean insurance market around the global financial crisis and the COVID-19 pandemic period. We pointed out economic factors that affect VI demand, and confirmed VI demand increases with stock market boom, low interest rate, high price level, and stable economic situation. Also consumers who decide to purchase VI usually consider the size, safety and profitability of a target insurance company. The asset and equity size have positive relationship with VI sales. Also reputation in traditional insurance market helps companies to attract new VI customers. The increase in the number of sales organization and sales person positively affects VI sales. From the analysis, we notice that more risk averse VI customers would choose domestic companies. Foreign companies have very active marketing strategies using young and highly educated sales persons targeting less risk averse VI customers.
An Empirical Study on the Perception of Health Risk Factors in Field Fire Officials: Focused on Fire Fighters, Rescue Workers and Emergency Medical
Authors:   Crisis and Emergency Management: Theory and Praxis, Yim Dong Kyun , Kim Si Kuk
Published: June 2022

In this study, we empirically examined risk factors that affect health for firefighting civil servants nationwide, and tried to utilize the results to establish a health management improvement plan for firefighting civil servants in the field. To this end, we conducted an awareness survey on the risk factors associated with the work characteristics of fire suppression personnel, rescue personnel, and rescue personnel. In the analysis, the internal consistency reliability of the risk factor factors was examined to ensure the reliability. Next, latent factors were extracted through Exploratory Factor Analysis and factor analysis was performed. We also performed a one-way ANOVA to investigate the differences in risk factor perceptions between jobs. Through the examination of risk factors between each job, he suggested that an academic scale for on-site safety is necessary. He also suggested the need for organized expert committee activities to deal with hazardous chemicals that field personnel perceive as dangerous.
Pembelajaran Matematika dengan Pendekatan Problem Based Learning dalam Implementasi Kurikulum 2013
Authors: Wahyuningsih Endang
Published: June 2022

Matematika merupakan ilmu universal yang mendasari perkembangan teknologi modern dan mempunyai peran penting dalam berbagai disiplin ilmu. Setiap orang dirasa perlu untuk mempelajari dan memahami matematika. Pengetahuan matematika harus diajarkan sejak dini. Akan tetapi, sebagian besar siswa menganggap matematika merupakan pelajaran yang sulit. Kesulitan siswa dapat dilihat dari rendahnya hasil UN matematika Tahun Ajaran 2018/2019. Kenyataan tersebut berimplikasi pada kualitas pembelajaran matematika yang perlu ditingkatkan. Salah satu pendekatan pembelajaran yang dipandang efektif dalam pembelajaran matematika adalah problem based learning (PBL). Berdasarkan hasil penelitian, PBL dikatakan mampu meningkatkan siswa berpikir dan memecahkan masalah dalam kehidupan nyata yang diperlukan untuk memenuhi kebutuhan pendidikan masa kini. Saat ini, kurikulum yang sedang berlangsung di Indonesia adalah Kurikulum 2013 (K13). Dalam K13 , pendekatan saintifik adalah salah satu pendekatan yang direkomendasaikan. Pendekatan Kurikulum 2013 dapat meningkatkan kreativitas peserta didik. Pendekatan saintifik merupakan pembelajaran yang menggunakan tahapan 5M yaitu mengamati, menanya, mengumpulkan informasi (melakukan percobaan), mengolah informasi (melakukan penalaran), dan mengkomunikasikan hasil. Selain itu, dalam implementasi K13, guru hendaknya tidak langsung memberikan rumus-rumus yang sudah siap pakai, tetapi siswa sebaiknya dilibatkan dalam penemuan rumus tersebut. Salah satu usaha guru untuk memfasilitasi kegiatan tersebut adalah dengan membuat Lembar Kegiatan Siswa (LKS). Oleh karena itu, dalam pelaksanaan pembelajaran matematika dengan pendekatan PBL juga harus disesuaikan dengan tuntutan Kurikulum 2013. Dengan demikian, pembahasan pada artikel ini akan menghasilkan: (1) rancangan kegiatan pembelajaran matematika (khususnya pada sub topik keliling lingkaran) dengan pendekatan PBL yang memuat tahapan 5M sebagaimana yang diharapkan dalam implementasi K13, (2) rancangan LKS yang tidak hanya berisi latihan soal-soal, tetapi juga memuat sekumpulan kegiatan untuk memaksimalkan pemahaman siswa.
Eksplorasi Etnomatematika pada Permainan Tradisional Layangan (Pemahaman Materi Bangun Datar Layang-Layang dan Pengembangan Karakter)
Authors: Kuswidi Iwan , Lestari Devinta Fajar , Arfinanti Nurul , Azka Raekha
Published: June 2022

Etnomatematika dapat menciptakan pembelajaran yang lebih bermakna dan menarik bagi perserta didik.  Selain itu, dapat menumbuhkan rasa cinta terhadap budaya lokal. Penelitian ini bertujuan untuk mengeksplorasi etnomatematika dan mengkaji lebih mendalam tentang konsep matematika pada permainan tradisional layangan, menggunakan metode penelitian kualitatif dengan pendekatan etnografi. Hasil analisis dan pembahasan, menunjukkan bahawa terdapat etnomatematika pada permainan tradisional layangan. Pada bagian kerangka layangan terdapat konsep dasar matematika seperti garis, panjang diagonal, titik sudut, dan sudut. Berdasarkan pengamatan bentuk layangan dapat diperoleh rumus keliling dan luas layang-layang melalui pendekatan dua segitiga kongruen dan dua segitiga sama kaki pada bangun layang-layang. Selain terdapat unsur matematika, permainan tradisional layangan memiliki peran dalam penanaman karakter bagi peserta didik. Sehingga dapat disimpulkan bahwa layangan dapat digunakan sebagai media dalam pembelajaran matematika.
Short‐term arm immobilization modulates excitability of inhibitory circuits within, and between, primary motor cortices
Authors: King Erin M. , Edwards Lauren L. , Borich Michael R.
Published: June 2022

Previous research has suggested that short‐term immobilization of the arm may be a low‐cost, non‐invasive strategy to enhance the capacity for long‐term potentiation (LTP)‐like plasticity in primary motor cortex (M1). Short‐term immobilization reduces corticospinal excitability (CSE) in the contralateral M1, and interhemispheric inhibition (IHI) from ipsi‐ onto contralateral M1 is increased. However, it is unclear whether reduced CSE and increased IHI are associated with changes in intracortical inhibition, which has been shown to be important for regulating neuroplasticity in M1. The current study used transcranial magnetic stimulation to evaluate the effects of short‐term (6 h) arm immobilization on CSE, IHI, and intracortical inhibition measured bilaterally in 43 neurotypical young adults (23 immobilized). We replicated previous findings demonstrating that immobilization decreased CSE in, and increased IHI onto, the immobilized hemisphere, but a significant change in intracortical inhibition was not observed at the group level. Across individuals, decreased CSE was associated with a decreased short‐interval intracortical inhibition, an index of GABAA‐ergic inhibition, within the immobilized hemisphere only in the immobilization group. Previous research has demonstrated that decreases in GABAA‐ergic inhibition are necessary for the induction of LTP‐like plasticity in M1; therefore, decreased intracortical inhibition after short‐term arm immobilization may provide a novel mechanism to enhance the capacity for LTP‐like plasticity within M1 and may be a potential target for strategies to augment plasticity capacity to enhance motor learning in health and disease.
Sports activities at a young age decrease hypertension risk—The J‐Fit+ study
Authors: Kumagai Hiroshi , Miyamoto‐Mikami Eri , Someya Yuki , Kidokoro Tetsuhiro , Miller Brendan , Kumagai Michi Emma , Yoshioka Masaki , Choi Youngju , Tagawa Kaname , Maeda Seiji , Kohmura Yoshimitsu , Suzuki Koya , Machida Shuichi , Naito Hisashi , Fuku Noriyuki
Published: June 2022

This study aimed to assess (1) blood pressure between young, current athletes, and non‐athletes early in life; (2) hypertension prevalence between former athletes and the general population later in life; and (3) understand the mechanisms between exercise training and hypertension risks in the form of DNA methylation. Study 1: A total of 354 young male participants, including current athletes, underwent blood pressure assessment. Study 2: The prevalence of hypertension in 1269 male former athletes was compared with that in the Japanese general population. Current and former athletes were divided into three groups: endurance‐, mixed‐, and sprint/power‐group. Study 3: We analyzed the effect of aerobic‐ or resistance‐training on DNA methylation patterns using publicly available datasets to explore the possible underlying mechanisms. In young, current athletes, the mixed‐ and sprint/power‐group exhibited higher systolic blood pressure, and all groups exhibited higher pulse pressure than non‐athletes. In contrast, the prevalence of hypertension in former athletes was significantly lower in all groups than in the general population. Compared to endurance‐group (reference), adjusted‐hazard ratios for the incidence of hypertension among mixed‐ and sprint/power‐group were 1.24 (0.87–1.84) and 1.50 (1.04–2.23), respectively. Moreover, aerobic‐ and resistance‐training commonly modified over 3000 DNA methylation sites in skeletal muscle, and these were suggested to be associated with cardiovascular function‐related pathways. These findings suggest that the high blood pressure induced by exercise training at a young age does not influence the development of future hypertension. Furthermore, previous exercise training experiences at a young age could decrease the risk of future hypertension.
Avoiding the news to participate in society? The longitudinal relationship between news avoidance and civic engagement
Authors: Ohme Jakob , Bruin Kiki de , Haan Yael de , Kruikemeier Sanne , Meer Toni G.L.A. van der , Vliegenthart Rens
Published: June 2022

Lower levels of news use are generally understood to be associated with less political engagement among citizens. But while some people simply have a low preference for news, others avoid the news intentionally. So far little is known about the relationship between active news avoidance and civic engagement in society, a void this study has set out to fill. Based on a four-wave general population panel survey in the Netherlands, conducted between April and July 2020 (N = 1,084) during a crisis situation, this research-in-brief investigates the development of news avoidance and pro-social civic engagement over time. Results suggest that higher news topic avoidance results in higher levels of civic engagement. The study discusses different explanations for why less news can mean more engagement.
Supervision method of indoor construction engineering quality acceptance based on cloud computing
Authors: Zhang Jian
Published: June 2022

As an important part of Chinese economy, the construction industry has a great contribution to the economy, and plays an important role in the Chinese economic development. Therefore, it has certain research significance for the quality acceptance supervision method of construction engineering. This article takes Shenzhen S project as an example, combined with cloud computing, discusses the quality acceptance and supervision methods of indoor construction projects. In the introduction to the technical part, this article first briefly introduces the definition of cloud computing and then introduces the particle swarm algorithm and traditional genetic algorithm in the cloud computing task scheduling method. The algorithm is introduced into the quality acceptance of indoor construction projects to obtain the quality, most efficient method for acceptance supervision. The experimental part of this article takes S project as the research object and the residents’ satisfaction with the project as the experimental purpose. Finally, through statistical analysis, it is concluded that the residents’ satisfaction with S project reaches more than 70%.
Ein neuartiges Konzept für 5D Nanopositionier-, Nanomess-,und Nanofabrikationsmaschinen
Authors: Leineweber Johannes , Meyer Christoph , Füßl Roland , Theska René , Manske Eberhard
Published: June 2022

In den vergangenen Jahren wurden an der TU-Ilmenau zahlreiche Entwicklungen im Bereich der Nanopositionier- und Nanomesstechnik realisiert. Insbesondere die NMM-1 [Gerd Jäger, Eberhard Manske, Tino Hausotte, Jans-Joachim Büchner, Nanomessmaschine zur abbefehlerfreien Koordinatenmessung, tm – Technisches Messen, 67(7–8), 2000] sowie die NPMM-200 [Eberhard Manske, Gerd Jäger, Tino Hausotte, Felix Balzer, Nanopositioning and Nanomeasuring Machine NPMM-200 – sub-nanometre resolu-tion and highest accuracy in extended macroscopic working areas, euspen’s 17th International Conference, 2017] stellen ein Novum auf dem Gebiet der Koordinatenmesstechnik mit Nanometerpräzision unter Einhaltung des Abbe-Komparatorprinzips [Ernst Abbe, Messaparate für Physiker, Zeitschrift für Instrumentenkunde, 10:446–448, 1890] dar. Ausgehend von diesen Errungenschaften besteht ein nächster Schritt im Messen und Fabrizieren auf stark gekrümmten, asphärischen, oder freigeformten Oberflächen. Vor jenem Hintergrund wird im folgenden Artikel ein Konzept für ein zweiachsiges Rotationsmodul vorgestellt. Dieses dient als Erweiterung für die NMM-1 und ermöglicht über das kartesische Messvolumen von

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25\hspace{0.1667em}\text{mm}\times 25\hspace{0.1667em}\text{mm}\times 5\hspace{0.1667em}\text{mm}

hinaus zusätzlich eine Rotation des Tools über 360 ° um die Hochachse sowie 60 ° Neigung. Die Umsetzung erfolgt über eine neuartige sphärische Parallelkinematik. Mit Hilfe eines interferometrischen In-Situ-Referenzmesssystems können die während der Rotationsbewegungen auftretenden translatorischen Positionsabweichungen detektiert werden. Erste Untersuchungen an einem Prototypenaufbau erbringen den Funktionsnachweis des Referenzmesssystems über den gesamten adressierbaren Winkelbereich.
Die nichtfinanzielle Berichterstattung – Analyse der Herausstellungsmöglichkeiten von Genossenschaftsbanken und Sparkassen und das Vorgehen in der Berichtspraxis
Authors: Helms Nils
Published: June 2022

Die nichtfinanzielle Berichterstattung, oftmals auch als Nachhaltigkeitsberichterstattung bezeichnet, gewinnt immer größere Bedeutung im Rahmen der Unternehmensberichterstattung. Zielsetzung des Beitrags ist die Analyse, inwieweit Genossenschaftsbanken und Sparkassen in ihrer nichtfinanziellen Berichterstattung ihre Alleinstellungsmerkmale, die eindeutige Nachhaltigkeitsbezüge aufweisen, herausarbeiten. Um dies empirisch überprüfen zu können, werden zunächst Kriterien zur Herausstellung der Spezifika abgeleitet, die dann mit Hilfe einer qualitativen Inhaltsanalyse ausgewertet werden. Im Ergebnis zeigt sich, dass sowohl die Genossenschaftsbanken als auch die Sparkassen ihre Besonderheiten hinsichtlich der Nachhaltigkeit hervorheben, aber in einigen Themengebieten (z. B. lokale Aktivitäten, Mitbestimmung) eine noch stärkere Herausarbeitung möglich wäre.
Predicting Students' Digital Entrepreneurial Intention: The Mediating Role of Knowledge and Inspiration
Authors: Wibowo Agus , Narmaditya Bagus Shandy
Published: June 2022

This study was intended to investigate how the direct effect of digital entrepreneurship education on digital entrepreneurship intentions and reveal the mediating role of knowledge and entrepreneurial inspiration. Our quantitative approach uses survey methods to address the proposed hypotheses. Approximately 340 students in five and seventh grade from Universitas Negeri Jakarta were participated as volunteers in this study. Moreover, the collected data were analyzed by using SEM-PLS with SmartPLS 3.0. The findings remarked that digital entrepreneurship education could promote students’ digital entrepreneurship intentions. This study provided insights related to psychological aspects in the form of entrepreneurial inspiration as one of the predictor variables and mediators for increasing digital entrepreneurship intentions. This research also confirmed that entrepreneurial knowledge took a role as a mediator for digital entrepreneurial intentions. This research is the first step to exploring further the critical role of digital entrepreneurship education as the right strategy to enhance the number of new entrepreneurs.
Primary adrenal insufficiency in a patient with biallelic QRSL1 mutations
Authors: Dursun Fatma , Genc Hulya Maras , Mine Yılmaz Ayşe , Tas Ibrahim , Eser Metin , Pehlivanoglu Cemile , Yilmaz Betul Karademir , Guran Tulay
Published: June 2022

Background

Biallelic QRSL1 mutations cause mitochondrial ‘combined oxidative phosphorylation deficiency-40’ (COXPD40). COXPD40 has been reported to be invariably lethal in infancy. Adrenal insufficiency was weakly reported and investigated among seven previously reported patients with COXPD40.

Objective

We report the clinical, biochemical, molecular, and functional characteristics of a patient with adrenal insufficiency due to COXPD40.

Methods

The medical history and adrenal function tests were examined. Genetic analysis was performed using whole-exome sequencing. Mitochondrial function was tested using mitochondrial membrane potential (MMP) and superoxide dismutase (SOD) enzyme assays.

Results

An 8-year-old boy was investigated for adrenal insufficiency. He also had mild developmental delay, sensorineural hearing loss, hypertrophic cardiomyopathy, nephrocalcinosis, elevated parathyroid hormone and creatine kinase, and lactic acidosis. Biallelic novel QRSL1 variants (c.300T>A;Y100* and c.610G>A;G204R) were identified. Oxidative damage in mitochondria was shown by reduced MMP and SOD assays in the patient compared to controls (P < 0.0001). Adrenal function tests revealed a ‘primary adrenal insufficiency other than congenital adrenal hyperplasia’ (non-CAH PAI) with an isolated glucocorticoid deficiency. In the 8-year follow-up, having the longest survival of reported COXPD40 patients, he had preserved mineralocorticoid functions and gonadal steroidogenesis.

Conclusion

Biallelic QRSL1 mutations can cause non-CAH PAI. Adrenal functions should be monitored in mitochondrial disorders to improve clinical outcomes.
Hacia un nuevo modelo pedagógico para la enseñanza y aprendizaje del Derecho: algunas apreciaciones desde una perspectiva crítica
Authors: Baltodano Mayorga José Daniel
Published: June 2022

Due to multiple critiques of traditional pedagogy and its impact on the education of legal professionals, some recommendations have been made which include adopting alternative pedagogical approaches, implementing curriculum changes, and introducing new didactic and evaluation strategies, among others. Nevertheless, it is appropriate to analyze whether these suggested changes are sufficient to overcome the traditional pedagogical model. This essay intends to examine the possibilities of a new pedagogical model for Law teaching and learning, taking into consideration elements such as exercising pedagogical authority and instructors’ capacity to reflect on their own praxis. Therefore, it is suggested that renovating the pedagogical model entails an integral approach that includes different dimensions, especially the epistemological and political ones before tackling formal or methodological aspects.
Saber, poder y justicia: una aproximación decolonial a la deconstrucción epistémica de la educación
Authors: Sánchez Lara Ricardo , Druker Ibáñez Sofía
Published: June 2022

This essay proposes a deconstructive approach of structural coordinates that, situated at the intersection of being, knowledge and power, are institutionalized as governmentality devices that organize educational narratives of domination. These narratives are sustained by objectivist and reifying epistemological assumptions articulating hegemonic constructions of knowledge, as a condition for the updating of exclusion systems based on colonial discourses and practices that produce and perpetuate subalternized otherness. Putting the premise of ontological reality in parentheses, we address the relationship between being, knowledge and power as an educational justice issue, focusing on the dimensions of distribution, recognition and participation as axes for the displacement of educational scenarios embedded in colonial frameworks.
El libro cartonero: inclusión y acceso a la información desde el trabajo colaborativo
Authors: Viera Iván Ariel
Published: June 2022

This essay aims to analyze the possibilities of a process of social inclusion by linking the way of working of a cardboard publisher and its strength as a social movement, with the aim of reflecting on the opportunities of generating inclusive actions to democratize access to information. This publisher finds its anchor in the publisher-society binomial and in the knowledge that is put into play as capital to satisfy the needs of the links that are generated. It will inquire how their policies make the problem of social exclusion and the marginalization of vulnerable sectors visible. The focus will be placed, then, on the activity of the cardboard publisher with respect to the form of cooperative and collaborative work and its possibilities as a form of social inclusion.
Comentario del libro Exiliados, expatriados e integrados: chilenos en Costa Rica (1973-2018), de Mario Oliva Medina (coordinador)
Authors: Rebolledo González Loreto
Published: June 2022

A comment is made on this book, coordinated by Mario Oliva and published by the National University Editorial in 2021, which is the result of an exhaustive and rigorous investigation supported by a variety of written and oral sources. Four chapters address the solidarity received by the Chileans who arrived in Costa Rica after the coup, considering the political and sociocultural dimensions of their integration, the insertion of academics in various universities; the meanings that exiles assign to the exile experience based on their subjectivities and a look at the exile of the painter Julio Escámez Carrasco. It is remarkable and novel that the text is located in the host country, with its center in the Chilean exiles but in a permanent dialogue with the context of the country to which they arrived and were integrated, showing how their presence had repercussions in various spheres of Costa Rican society generating mutual benefits.
How Routine are Routine Vital Signs?
Authors: McDaniel Lauren M. , Ralston Shawn L.
Published: June 2022

BACKGROUND AND OBJECTIVES

Frequent measurement of vital signs has been associated with disruptions to sleep and increased nursing workload. Since vital signs are often measured at the same frequency regardless of patient acuity, there may be inappropriate prioritization of limited resources. We sought to understand what hospitalists report as the default frequency of routine vital sign measurement in hospitalized pediatric patients at academic institutions.

METHODS

We surveyed pediatric hospital medicine leadership at Association of American Medical Colleges-affiliated medical schools on their perception of routine vital signs in general medicine inpatients.

RESULTS

Survey requests were sent to individuals representing 140 unique hospitals. Responses were received from 74 hospitalists, representing a 53% response rate. Routine vitals were most commonly characterized as those collected every 4 hours (78%; 95% confidence interval, 67%–87%), though at least 1 in 5 hospitalists reported obtaining all or select vital signs (eg, blood pressure) less frequently. Strategies to decrease vital sign frequency varied.

CONCLUSIONS

Our results suggest routine vital signs are not a normative concept across all patient populations in pediatrics. We further identify several conditions under which deviation from routines are sanctioned.
Feasibility, accuracy and advantages of frozen section examination of ovarian masses with normal tumor markers. A tertiary referral center experience
Authors:   Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt, Elfeky Abeer , Hamdy Omar ,   Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt, Roshdy Sameh ,   Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt, Shahatto Fayez ,   Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt, Abdelaziz Mahmoud ,   Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt
Published: June 2022

Introduction: Proper design of the operative plan for patients with ovarian masses is a must to avoid unnecessary surgical steps, the need for another surgery or empirical chemotherapy. We investigated the role of frozen section examination in this design. Methods: This was a prospective study in which 64 complex adnexal masses with normal tumor markers underwent frozen section examination. The patients were divided into two parallel groups: group A in which the decision whether to proceed for complete staging or not was built on the result of the examination, and group B in which the patients underwent panhysterectomy at baseline regardless of their frozen section examination result. Postoperative stay, estimated blood loss and the incidence of complications were compared. Results: When comparing the two groups, including patients with tumors that turned out to be benign, there were no significant differences in postoperative complications, but there were for the operative time (60 vs. 120 minutes, p = 0.004) and blood loss, which were significantly lower in group A (50 vs. 100 mL, p = 0.001), and hospital stay, which was statistically insignificantly shorter than in group B (1 day vs. 2 days, p = 0.062). The sensitivity of frozen section examination for benign, borderline, and malignant ovarian masses was 91.9%, 76.9%, 53.3%, respectively, while the specificity was 85.2%, 87.5%, 95.9% and the overall diagnostic accuracy was 89.6%, 85.2%, 85.9%, respectively. Conclusion: The use of frozen section examination in the assessment of complex ovarian masses in patients with normal tumor markers offers an acceptable accuracy with a significant decrease of the operative time, blood loss as well as hospital stay.
PARP inhibitors – a new direction in the treatment of breast and ovarian cancer
Authors:   Student Research Club at the Department of Obstetrics, Women’s Diseases and Gynecologic Oncology, Medical University of Warsaw, Warsaw, Poland, Gawalski Karol , Bizoń Magdalena ,   Department of Obstetrics, Gynecology and Gynecologic Oncology, Medical University of Warsaw, Mazovian Bródnowski Hospital, Warsaw, Poland, Dźwigała Bohdan ,   Department of Obstetrics, Gynecology and Gynecologic Oncology, Medical University of Warsaw, Mazovian Bródnowski Hospital, Warsaw, Poland, Cendrowski Krzysztof ,   Department of Obstetrics, Gynecology and Gynecologic Oncology, Medical University of Warsaw, Mazovian Bródnowski Hospital, Warsaw, Poland, Sawicki Włodzimierz ,   Department of Obstetrics, Gynecology and Gynecologic Oncology, Medical University of Warsaw, Mazovian Bródnowski Hospital, Warsaw, Poland
Published: June 2022

Ovarian cancer, like breast cancer, may either develop spontaneously or as a result of a family history. BRCA1 and BRCA2 mutations significantly increase the risk of both cancers at all ages. It is estimated that 3–5% of women are BRCA mutation carriers. BRCA1 mutation carriers have a 65% risk of breast cancer and 39% risk of ovarian cancer. These risks are lower among BRCA2 mutation carriers, i.e. 45% and 11% for breast and ovarian cancer, respectively. In breast and ovarian cancer with BRCA mutations, blocking the function of poly(ADP-ribose) polymerase (PARP) enzymes, including PARP1 and PARP2, causes an accumulation of DNA damage that ultimately leads to cancer cell death. Based on this mechanism, PARP inhibitors have been used in the treatment of hereditary neoplasms, in which the proper functioning of DNA damage repair systems is disturbed. In clinical trials to date, PARP inhibitors significantly extended the progression-free survival in patients with confirmed BRCA mutations. Similar results have been obtained for patients without confirmed genetic background. Currently, PARP inhibitors are increasingly approved for use in the treatment of ovarian and breast cancer. From May 2021, the Ministry of Health has reimbursed maintenance therapy with PARP inhibitors in patients with known BRCA mutation status.
The effect of calf gender on milk lactation traits and lactation gain of Holstein and Simmental cows
Authors:   Ministry of Agriculture, Sector for Livestock Production, Ilica 101, 10000 Zagreb, Croatia, Čačić Mato
Published: June 2022

Considering the challenging market conditions for dairy farms, calf gender management should be one of the tools used to increase profitability. The objective of this paper was to examine the effect of calf gender on lactation milk traits in Holstein and Simmental cows. Holstein cows that calved a female calf had a higher milk yield (p<0.0001) and lower milk fat and protein content (p<0.01) in the first lactation. The favourable effect of female calf on milk yield was also found in the second lactation of Holstein cows (p<0.0001). Simmental cows that calved female calves in the first and the second lactation also had higher milk yield and lactation gain, however the differences were not significant. Although no statistically significant effect of calf gender on milk yield was determined in the Simmental population, indications of positive effect of female calf gender on lactation milk yield impose the need for further research. Using gender selected semen as a tool for calf gender management could enable to increase the milk yield of Holstein cows and the profitability of Holstein farms as well.
Perubahan Pola Sakramen Umat Katolik Bandung Pada Era Pandemi Covid-19
Authors: Viktorahadi R.F. Bhanu
Published: June 2022

During the Covid-19 pandemic, Catholics in Bandung had difficulty understanding the Sacrament as a means and sign of salvation from God. This difficulty arises because people can only follow and celebrate the Sacraments, especially the Eucharist or Mass online. The absence of direct encounter causes reduction and degradation of appreciation of the efficacy or effectiveness of online Masses as a means and a sign of safety. People desperately need a program that can increase their understanding of the Sacrament's efficacy, especially online Mass. For this reason, the Center for Philosophy, Culture and Religious Studies, Faculty of Philosophy, Parahyangan Catholic University (CPCReS FF UNPAR) Bandung, in collaboration with the Theological Science Community (KBI) Faculty of Philosophy UNPAR, held an Extention Course Theology (ECT). The program that uses the dialogue method is followed by Catholics in Bandung online by involving speakers with theological backgrounds from FF UNPAR. The evaluation results show that the material from this course can increase understanding of the efficacy of the sacrament, especially in this Pandemic era.
El tortuoso camino hacia la justa distribución de la renta y de la riqueza
Authors: Benítez-Aurioles Beatriz
Published: June 2022

La información estadística disponible apunta hacia un crecimiento de la desigualdad de la renta y de la riqueza en la última década, lo cual ha estimulado el debate sobre las políticas más adecuadas para revertir el proceso. La discusión gira en torno a la definición del objetivo que se pretende alcanzar, la forma más adecuada de medirlo y los instrumentos que deben emplearse, teniendo en cuenta los efectos colaterales de las medidas implementadas. En este contexto, surge la oportunidad para que las empresas refuercen su compromiso social procurando, en su ámbito de actuación, la justicia distributiva.
Urban–Rural Differences in Drug Overdose Death Rates, 2020
Authors:   National Center for Health Statistics (U.S.), Spencer Merianne Rose , Garnett Matthew F. , Miniño Arialdi M.
Published: June 2022

This report uses the most recent final mortality data from the National Vital Statistics System to describe urban and rural differences in drug overdose death rates in 2020, by sex, race and Hispanic origin, and selected types of opioids and stimulants.
A roadmap for designing narrow-spectrum antibiotics targeting bacterial pathogens
Authors: Cao Xinyun , Landick Robert , Campbell Elizabeth A.
Published: June 2022

Clostridioides difficile (Cdiff) infection (CDI) continues to be the leading threat of nosocomial deaths worldwide and a major burden on health-care systems. Broad-spectrum antibiotics eradicate the normal gut microbiome, killing protective commensal bacteria and increasing CDI recurrence. In contrast, Fidaxomicin (Fdx) is a narrow-spectrum antibiotic that inhibits Cdiff growth without affecting crucial gut microbes. However, the basis of the narrow-spectrum activity of Fdx on its target, RNA polymerase (RNAP), in Cdiff has been enigmatic. Recently, Cao et al. (Nature, doi: 10.1038/s41586-022-04545-z) combined transgenic RNAP design and synthesis with cryo-electron microscopy (cryo-EM) to identify a key determinant of Fdx inhibition of Cdiff RNAP. This finding was further corroborated by biochemical, bioinformatics, and genetic analysis. This microreview describes implications of this work for lineage-specific antibiotic design and new directions toward understanding transcription and regulation in Cdiff and other bacterial pathogens.
Aktywność parlamentarna senatorów II Rzeczypospolitej na przykładzie obecności Narodowej Demokracji w Senacie II kadencji (1928–1930)
Authors:   Uniwersytet Kazimierza Wielkiego, Meller Arkadiusz
Published: June 2022

The following article provides an outline of a lesser known historical phenomenon related to the actions of Polish parliamentary politicians of the National Democracy (ND) formation in the years 1928-1930. In stark contrast to the elections of 1922, the elections of 1928 resulted in the defeat of the Nationalist camp, which ended up having only nine ND politicians. First, the article sketches a sociological map of ND senators. Secondly, it delves into the activities of senators in particular Senate boards, therefore explaining the real impact these people had on the workings of the higher chamber. Finally, an analysis of various statements is conducted with the aim of summarising the political views of these senators as well as the main issues they focused on, including state administration, justice, local governance, education and foreign policy.
Rola Europejskiego Urzędu ds. Bezpieczeństwa Żywności w zapewnianiu bezpieczeństwa biologicznego na przykładzie Afrykańskiego Pomoru Świń
Authors:   Uniwersytet Kazimierza Wielkiego, Panciszko Barbara
Published: June 2022

Przedmiotem artykułu jest problematyka zagrożenia biologicznego w państwach członkowskich Unii Europejskiej, jakim jest wirus Afrykańskiego Pomoru Świń (ASF). Celem było określenie roli Europejskiego Urzędu ds. Bezpieczeństwa Żywności (EFSA) w procesie analizy ryzyk biologicznych oraz wskazanie funkcji, jakie pełni w systemie instytucjonalnym UE. Postawiono hipotezę badawczą: rekomendacje wydawane w opiniach naukowych publikowanych przez EFSA są podstawą decyzji wykonawczych Komisji Europejskiej. Korespondują z nią pytania badawcze: Jaka jest skala zagrożeń związanych z wirusem ASF? Jakie kompetencje ma EFSA w procesie analizy ryzyk biologicznych? Jak ewoluowało podejście EFSA, co do zalecanych narzędzi zarządzania ryzykiem związanym z wirusem ASF? Kiedy i w jakich przypadkach EFSA podejmuje badania naukowe dotyczące ASF? W opracowaniu wykorzystano metodę case study oraz posłużono się techniką desk research.
Ceratitis capitata (Wiedemann,1824) (Diptera: Tephritidae)’nin İzmir, Aydın ve Mersin Şeftali Bahçelerinde kitle yakalama tekniğinin etkinliğinin belirlenmesi
Authors: Yayla Miraç , Tolga Mehmet Fatih , Helvacıoğlu Özge , Kahya Doğancan
Published: June 2022

Ceratitis capitata karantina zararlısı ve toleransı sıfır olarak kabul edilen bir türdür. Üreme kapasitesinin yüksek olması ve doğrudan meyvede zarar yapması nedeniyle zararlı ile mücadele yürütülmeden üretim yapmak mümkün olamamaktadır. Kimyasal mücadeleye alternatif olarak biyoteknik mücadele yöntemi olan kitle halinde tuzakla yakalama, zararlının çok yüksek olmayan popülasyonlarında başarılı sayılan bir mücadele şeklidir. Tuzaklar ile mücadelede farklı besin cezbedici materyaller kullanılarak bireylerin tuzağa çekilmesi sonucu öldürülmesi sağlanmaktadır. Bu çalışma, Ege ve Akdeniz Bölgelerinde şeftali bahçelerinde eş zamanlı yürütülmüş ve bölgeler arasındaki popülasyon farklılığına göre tuzakların etkinliğinin belirlenmesi amaçlanmıştır. Denemeler 2018 yılında Kuşadası (Aydın), Selçuk (İzmir) ve Erdemli (Mersin) ilçelerinde yürütülmüştür. Zararlının feromon tuzaklar ile popülasyon değişimi ve kitle halinde yakalama tuzaklarının etkinliği saptanmıştır. Mücadele tuzağı olarak Decis Trap (Bayer) isimli ürün kullanılarak tuzağın etkinlikleri saptanmıştır. Temmuz ayında Kuşadası, Selçuk ve Erdemli ilçelerinde sırasıyla 4.8, 149.1 ve 166.9 adet/tuzak ergin birey yakalamıştır. Buna göre Kuşadası ilçesinde %94.19, Selçuk ilçesinde %95.6 oranlarında etkili bir başarı sağlarken Erdemli ilçesinde %56.34 oranında etkili olmuştur. Akdeniz Bölgesi popülasyonunun Ege Bölgesine göre daha yüksek seyretmesi ve şeftali üretim sezonun daha uzun sürmesinden dolayı istenilen düzeyde başarı sağlanamadığı belirlenmiştir.
New data on the tribe Osmiini (Hymenoptera: Megachilidae) fauna of Türkiye
Authors: Kaplan Emin
Published: June 2022

Ten species belonging to the tribe Osmiini were collected and identified from the east of Türkiye during 2017-2021. The specimens were identifed as Chelostoma emarginatum (Nylander, 1856), Heriades rubicola Pérez, 1890, Hoplitis leucomelana (Kirby, 1802), Hoplitis tridentata (Dufour and Perris, 1840, Hoplitis (Anthocopa) serainae Müller, 2012, Hoplitis (Hoplitis) sp., Osmia aurulenta (Panzer, 1799), Osmia gallarum Spinola, 1808, Osmia (Helicosmia) signata Erichson, 1835 and Osmia viridana Morawitz, 1874. Distributions, illustrations and brief descriptions of all species are added to the study. No new records were obtained but new localities for some species have been reported.