bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Hematologic Parameters in Predicting Orchiectomy for Testicular Torsion
Authors: Çanakcı Cengiz , Dinçer Erdinç , Özkaptan Orkunt , Sevinç Medet , Eryıldırım Bilal
Published: June 2024

Objective: Testicular torsion is an urological emergency that requires early intervention. When torsion is diagnosed late, the possibility of organ loss increases. In this study, we investigated the role of preoperative hematological parameters in predicting orchiectomy. Material and Methods: A total of 136 patients who had undergone surgery due to testicular torsion were included in this study. Patients are divided into two groups as orchiectomy (n=48) and testicular fixation (n=88). The groups were compared with age, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), platelet count (PLT), mean platelet volume (MPV), neutrophil count, lymphocyte count, symptoms of duration, side and the degree of torsion. Results: The mean age was 18.2 ± 9.6 in orchiectomy group and 17.2 ± 6.1 in testicular fixation group (p=0.569). The symptoms of duration was statistically higher in orchiectomy group (57.4±35.7 vs. 8.7±7.4 (p=0.001)). NLR was 5.03±2.93 in orchiectomy group and 6.72±3.51 in testicular fixation group (p=0.005). MPV was found to be significantly higher in the orchiectomy group (p=0.001). There were no differences between the groups in terms of the PLR (p=0.137), PLT (p=0.251), neutrophil count (p=0.309) and lymphocyte count (p=0.895). In multivariate analysis, the degree of torsion and the duration of symptoms were found to be predictive for orchiectomy (p=0.003, p<0.001). Conclusion: Many studies have reported that preoperative haematological parameters predict orchiectomy. However, no predictive factor was found in our study.
تطبيق طريقة "باندوغان" في ترجمة الكتب العربية في معهد الوصايا كرطاريجا غورو جومبانج
Authors: M. Shoby Mubarok  , Rohman Fathur
Published: June 2024

Menerjemah adalah proses mengubah bahasa dari bahasa sumber kebahasa target. Pada kenyataannya, diera sekarang ini, masih banyak mahasiswa kesulitan memahami buku-buku Arab, terutama dalam terjemahan. Metode pembelajaran dipondok-pondok pesantren memiliki bentuk ciri khas yang berbeda dari lainnya. dan salah satunya adalah metode Bandungan yang digunakan oleh  pondok pesantren Washoya Kertarejo Jombang sebagai sarana untuk  menerjemahkan buku-buku Arab. Tujuan penelitian adalah: untuk mengetahui bagaimana menerapkan metode Bandongan dipondok washoya, dan untuk mengetahui menerjemahkan buku-buku Arab dengan menggunakan metode Bandongan, dan untuk mengetahui  factor pendukung dan penghambat dalam menerapkan metode Bandongan. Dalam penelitian ini, peneliti menggunakan metodologi penelitian deskriptif kualitatif. Adapun hasil penelitian ini, Pertama dalam penerapan metode Bandongan pondok washoya adalah guru membaca satu persatu kosakata dalam kitab dengan menggunakan simbol dan beberapa istilah tertentu, tetapi siswa menyimak kitanya dan menuliskan makna kosakata tersebut dan mereka juga tidak dapat berpartisipasi aktif dalam proses penerjemahan. kedua Penerjemahan buku-buku Arab dengan menerapkan metode Bandongan adalah literal dengan menerjemahkan kata demi kata atau jenis terjemah harfiyah. Yang ketiga factor pendukung dalam menerapkan metode Bandongan dalam pondok washoya adalah bagusnya penguasaan siswa dalam memahami kaidah bahasa Arab, adapun penghambatnya adalah kurangnya kedisiplinan siswa, kurangnya semangat siswa ketika memberi makna, dan mengantuk serta tidak memperhatikan guru.
A Study on Job Demands-Resources in the Public Sector
Authors: Tri Ongko Bayu Sadewo  , Nourma Mei Shinta
Published: June 2024

Purpose – This study aims to find out the effect of job demands, workload, job resources, autonomy, relevance, and competence, and personal resources, psychological capital in influencing job engagement, as well as testing the mediating role of burnout in public sector employees.
Methodology – Respondents in this study were 201 employees of the Fiscal Policy Agency, using proportionate stratified sampling. The data was analyzed using Structural Equation Modeling with AMOS.
Findings – The research showed that workload has a positive influence on burnout, while psychological capital, autonomy, and relatedness have negative influences on burnout. It is also demonstrated that psychological capital and relatedness have positive influences on job engagement, while burnout has a negative influence on job engagement. It cannot be proven that competence has a negative influence on burnout and a positive influence on job engagement. It was also found that burnout can mediate the relationship between workload, psychological capital, autonomy, and relatedness to job engagement. Still, it cannot mediate the relationship between competence and job engagement.
Originality – Studies related to job demand resources in the public sector are very limited and are mostly conducted in the healthcare sector. This research also considered the conditions of the Covid-19 pandemic.
Wearable sensors based on artificial intelligence models for human activity recognition
Authors: Alarfaj Mohammed , Al Madini Azzam , Alsafran Ahmed , Farag Mohammed , Chtourou Slim , Afifi Ahmed , Ahmad Ayaz , Al Rubayyi Osama , Al Harbi Ali , Al Thunaian Mustafa
Published: June 2024

Human motion detection technology holds significant potential in medicine, health care, and physical exercise. This study introduces a novel approach to human activity recognition (HAR) using convolutional neural networks (CNNs) designed for individual sensor types to enhance the accuracy and address the challenge of diverse data shapes from accelerometers, gyroscopes, and barometers. Specific CNN models are constructed for each sensor type, enabling them to capture the characteristics of their respective sensors. These adapted CNNs are designed to effectively process varying data shapes and sensor-specific characteristics to accurately classify a wide range of human activities. The late-fusion technique is employed to combine predictions from various models to obtain comprehensive estimates of human activity. The proposed CNN-based approach is compared to a standard support vector machine (SVM) classifier using the one-vs-rest methodology. The late-fusion CNN model showed significantly improved performance, with validation and final test accuracies of 99.35 and 94.83% compared to the conventional SVM classifier at 87.07 and 83.10%, respectively. These findings provide strong evidence that combining multiple sensors and a barometer and utilizing an additional filter algorithm greatly improves the accuracy of identifying different human movement patterns.
OPTIMALISASI KONSUMSI OLAHAN TELUR PUYUH TERHADAP PENINGKATAN KADAR HEMOGLOBIN IBU HAMIL
Authors: Mardianti Mardianti , Farida Yuli , Santi Mina Yumei , Arum Dyah Noviawati Setya , Trisnawati Irna
Published: June 2024

Kehamilan merupakan proses yang diawali dengan pembuahan sampai kelahiran. Kebutuhan gizi yang belum terpenuhi dan perubahan hormon dalam kehamilan menyebabkan tubuh kekurangan jumlah sel darah merah yang disebut dengan anemia dalam kehamilan. Beragam makanan untuk ibu hamil berfungsi efektif untuk menjaga kesehatan selama kehamilan, salah satunya adalah telur puyuh. Telur puyuh kaya akan vitamin sehingga olahan makanan dengan bahan utama telur puyuh dalam bentuk baso aci isi telur puyuh, merupakan upaya optimal meningkatkan gizi dalam mencegah anemia kehamilan. Penelitian ini bertujuan untuk mengetahui peningkatan kadar hemoglobin ibu hamil dan rata-rata kenaikan kadar hemoglobin ibu hamil yang mengonsumsi baso aci isi telur puyuh serta mengetahui perbedaan kadar hemoglobin ibu hamil setelah mengonsumsi baso aci isi telur puyuh. Jenis penelitian ini eksperimen dengan metode quasi eksperimen. Sampel terdiri atas 35 responden kelompok kasus dan 35 responden kelompok kontrol dengan teknik purposive sampling pada kriteria usia kehamilan ≥24 minggu tanpa komplikasi dan penyakit yang menyertai diwilayah kerja Puskesmas Rengasdengklok Karawang. Hasil penelitian didapatkan peningkatan kadar Hb pada ibu hamil anemia yang mengonsumsi baso aci isi telur puyuh sebesar 94% ,dengan rata-rata peningkatan kadar hemoglobin 1,47 gr%. Terdapat perbedaaan yang bermakna pada ibu hamil anemia yang mengonsumsi baso aci isi telur puyuh dengan nilai P=0.00. Bidan dalam layanan antenatal secara konsisten memotivasi ibu hamil untuk meningkatkan gizi selama kehamilan dengan memberikan makanan tambahan berupa olahan bakso aci isi telur puyuh, sehingga dapat meningkatkan kadar hemoglobin ibu selama kehamilan.
English day: Impact on motivation of english language teaching undergraduates
Authors: Agudelo Bedoya Alejandra , Aguilar-Cruz Paola Julie
Published: June 2024

This study investigates how the English Day, an extracurricular activity, influences intrinsic and extrinsic motivation among English as a Foreign Language (EFL) undergraduates. Conducted at a public university in Florencia, Caquetá, Colombia, the qualitative case study involved thirty (30) participants from the English Language Teaching (ELT) program at Universidad de la Amazonia. Through semi-structured interviews and grounded theory analysis, the research aimed to analyze the role of the English Day in motivating ELT undergraduates. Results revealed that the majority of participants felt intrinsically motivated to use English during the event. Interestingly, some initially reported extrinsic motivation, which transformed into intrinsic motivation upon participation in the English Day activities. This study provides valuable insights into how the English Day extracurricular activity influences both intrinsic and extrinsic motivation among undergraduates.
Prácticas de cuidado y resistencia en trabajadores de plataformas de reparto
Authors: Mendoza Sánchez Citlalli , Sahagún Padilla Miguel Angel
Published: June 2024

El presente artículo da cuenta de la articulación de prácticas de cuidado y resistencia frente a las condiciones de precarización laboral en el ámbito de las plataformas digitales de reparto. La precarización es abordaba como una forma de violencia que impacta la vida de los trabajadores. El objetivo es discutir las implicaciones de las prácticas de cuidado y resistencia que permiten hacer frente a esta problemática. La investigación se realiza desde un enfoque cualitativo, específicamente, echando mano del análisis documental y las entrevistas. Los participantes son trabajadores que forman parte de organizaciones que luchan por los derechos laborales en este sector. Los resultados evidencian prácticas colectivas de cuidado, orientadas a la construcción de condiciones de prosperidad para la vida de los repartidores, que buscan incidir en el ámbito laboral, social y político. Se concluye que las prácticas de cuidado y resistencia constituyen estrategias que han intentado mitigar las condiciones de precariedad laboral, al tiempo que han construido alternativas de cuidado con alcance local y global.
Síntese e caracterização de filmes de Polipirrol dopados com Tetraquis(4-carboxifenil) porfirina para aplicações fotoelectroquímicas
Authors: Guarin Felipe Martinez , Hernandez Martin Emilio Gonzalez , Puerres Jhon Danis Puerres , Montañez Maria Teresa Cortés
Published: June 2024

Photoelectrochemistry is emerging as a promising technology for harvesting and utilizing solar energy in a wide range of applications. However, electrode materials still need to be improved to achieve optimal performance. Conductive polymers emerge as particularly promising organic compounds for this purpose due to their highly versatile properties.
In this study, the galvanostatic synthesis of polypyrrole films co-doped with tetrakis(4-carboxyphenyl) porphyrin (PPy/TCPP) on fluorine doped tin oxide (FTO)-coated glass substrates was performed for the first time. In addition, an evaluation of these films as photoelectrodes was performed, focusing on key properties. The incorporation of porphyrin into the polymer matrix was confirmed by UV-Vis and IR characterization. SEM micrographs showed the morphological changes induced by the codopant. Cyclovoltammetry was used to evaluate the conductivity of the film, its electroactivity, electroactive area and HOMO energy level. The chopped chronoamperometry confirmed the photoactivity of the material and its stability for 3000 s. The electrical and optical properties of the polymer were characterized by EIS and light absorption measurements to propose its energy level diagram. The PPy/TCPP coatings were obtained with high homogeneity on FTO, good conductivity, quasi-reversible electrochemical activity to ferrocene probe and stable photoactivity. Electrical characterization indicates high charge flow under illumination. An indirect bandgap of 2.51 eV and a HOMO level value of -4.59 eV were obtained for PPy/TCPP.
O Plantão Psicossocial na Polícia Militar do Paraná: um suporte essencial para a saúde mental dos policiais militares
Authors: Penkal Rafael Cordasco , Rodrigues Caroline Bail
Published: June 2024

A profissão policial-militar foca na preservação da ordem pública, na proteção das pessoas e do patrimônio, também abrangendo medidas assistenciais e preventivas. No entanto, essas atividades podem, ocasionalmente, resultar em incidentes críticos que causam traumas psicológicos, comprometendo a habilidade adaptativa dos profissionais envolvidos. Sopesando a primordialidade de compreender os efeitos da vitimização policial e de melhorar as condições laborais e a saúde mental desses profissionais, criando um ambiente mais seguro para toda a sociedade, objetiva-se descrever o Plantão Psicossocial da Polícia Militar do Paraná (PMPR) como um modelo eficaz para reduzir os efeitos da vitimização policial. Mediante uma revisão sistemática de artigos, monografias e obras acadêmicas, observa-se que a resiliência e o suporte psicológico são essenciais para os policiais que enfrentam eventos traumáticos, visando minimizar os danos de um incidente crítico, sendo que esse suporte deve incluir toda a organização, promovendo a saúde mental e qualidade de vida dos profissionais. Em suma, este estudo destaca a magnitude do Plantão Psicossocial, para garantir um atendimento abrangente, mediante um suporte institucional robusto para enfrentar os desafios psicológicos inerentes à atividade policial, promovendo a saúde mental e a resiliência destes profissionais.
Percepção da comunidade acadêmica sobre questões ambientais: um estudo do programa Pet-Pesca
Authors: Maquiné Anderson Barroso , Santos Jerusa Halem do Nascimento , Santos Rômulo Ferreira dos , Bernardo Francinete Tobar , Nogueira João Marcos Miranda , Vasconcelos Karla Garcia , Souza João Victor Silva de , Yamamoto Kedma Cristine
Published: June 2024

Este estudo teve como objetivo investigar a percepção da comunidade acadêmica sobre questões ambientais, foi utilizado um questionário com perguntas fechadas, aplicado por meio do Google Forms, para abordar questões ambientais junto a uma comunidade acadêmica diversificada. A maioria dos participantes (65%) demonstrou alto interesse no meio ambiente, o que indica conscientização e engajamento no tema. A inserção de questões ambientais na formação educacional foi considerada "Muito importante" por 85% dos participantes, ressaltando a necessidade de uma educação ambiental efetiva. Ações sustentáveis, como visitas técnicas e parcerias com instituições industriais, foram apoiadas (30%), enquanto a coleta seletiva foi considerada uma importante ação para lidar com os resíduos do consumismo desenfreado (34%). A poluição das águas foi apontada como a questão ambiental mais preocupante (42%). Esses resultados fornecem informações significativas para o desenvolvimento de estratégias e políticas que promovam a sustentabilidade e preservação ambiental, enfatizando a importância da conscientização e ações práticas para enfrentar os desafios ambientais atuais.
La importancia de la diversidad y la inclusión laboral en las empresas
Authors: Bencomo Myrna Isela García , Sanchez Brenda Guadalupe Burciaga , Avila José Rene Arroyo , Diaz Del Rosario de Fátima Alvídrez , Magallanes Karinna Idalia Holguín , Rogel Rosa Nava , Zapata Armando Javier Cabrera
Published: June 2024

El presente artículo tiene como objetivo de analizar los conceptos de diversidad e inclusión laboral a través de diferentes enfoques basados en contexto cultural, social y legal. Las empresas suelen tener características similares en cuanto a raza religión, formación académica incluso nivel social, sin embargo, eso ha cambiado significativamente y debe de cambiar asumiendo   compromiso con la diversidad y la inclusión en todas las dimensiones de la compañía respondiendo con ello a las necesidades de vigencia y crecimiento como una empresa de clase mundial, enfocada a la responsabilidad social, al voluntariado corporativo y a la sustentabilidad. Estos aspectos son fundamentales y contribuyen de forma significativa en la mejora del clima laboral, toma de decisiones estratégicas y conexión con diferentes grupos de interés, destacando la importancia de la equidad, el respeto y la valoración como pilares fundamentales para alcanzar un entorno laboral más justo, inclusivo y productivo.
Sarau literário e cultural em um município do interior da Bahia: um relato de experiência
Authors: Celestino Aldésia Márcia de Freitas Vieira , Vieira Vilma Maria do Nascimento , Silva Geane da , Vieira Edinalva Cardoso Freitas , Araújo Herácliton Neves
Published: June 2024

Introdução: Assim, aspectos sociais da memória podem ser considerados como a memória social do indivíduo e como atos coletivos do lembrar e do esquecer. São tradições e traços da memória que representam diferentes abordagens que podem ser associadas a um mesmo fenômeno ou explicar diferentes acontecimentos classificados na memória. Objetivo: descrever a experiência do projeto de ampliação dos conhecimentos acerca da história e cultura da cidade de Campo Formoso e da região de Tiquara. Métodos: Este estudo trata-se de um relato de experiência. Neste Projeto foram apresentados o histórico de Campo Formoso, conhecimentos sobre a educação, saúde, riquezas naturais, símbolos do município, personalidades ilustres, aspectos econômicos, povoados, cultura e tradições da nossa cidade, com o objetivo de proporcionar a valorização e o respeito pela cidade, fazendo o aluno se reconhecer como membro desse contexto e participante da construção dessa história. Resultados e discussão: Refletir sobre a realidade atual e quais mudanças serão necessárias para atender a essa nova sociedade consiste em mudar ou adequar currículos, inovar práticas pedagógicas, modificar a estrutura física dos ambientes de aprendizagem para se adequar às mudanças sociais, entendendo assim o que Thomas Kuhn chama de ruptura paradigmática, onde contextos de aprendizagem são construídos pela interação dos pares dentro de um ambiente carregado de nutrientes cognitivos, contrariando os pressupostos do paradigma fabril.Considerações finais: Todas as propostas de atividades sugeridas pelos professores provocaram uma prática pedagógica concreta, construindo uma aprendizagem efetiva dos seus alunos. A superação das dificuldades dos alunos na leitura e escrita, percurso este construído dia após dia, com um desejo de mudança que vinha de dentro, perceptível no desenrolar das aulas e na vontade de aprender que era despertada nos alunos, colocando-os sempre como os protagonistas da ação no desenvolvimento da identidade e do espírito de pertencimento.
PENGARUH KETERSEDIAAN INFRASTRUKTUR TERHADAP KETIMPANGAN PENDAPATAN DI PROVINSI JAWA BARAT
Authors: Siswantoro
Published: June 2024

West Java is ranked third as the province with the highest level of income inequality in Indonesia. Equitable infrastructure development is one strategy to reduce income inequality in a region. This research aimed to examine the impact of the availability of infrastructure in the form of roads, educational facilities and health facilities as well as a control variable in the form of economic growth on income inequality in West Java. A total of 189 panel data from 27 districts and cities over a period of 7 years (2016-2022) were evaluated using a selected regression model (random effect model). The data source taken from the West Java Province Statistics Agency. The research results showed that the availability of road infrastructure is the dominant factor in reducing income inequality in West Java rather than education and health facilities. This is possible because road infrastructure encourages connectivity between regions, develops other facilities more evenly and increases business productivity so that people's income increases and ultimately reduces income inequality.
The Effect of Varenicline on Smoking Cessation in Hospitalized Patients: A Systematic Review and Meta-Analysis
Authors: Aryanpur Mahshid , Ghorbani Raheb , Rashno Sajjad , Heydari Gholamreza , Kazempour-Dizaji Mehdi , Hessami Zahra , Ghorbani Narges
Published: June 2024

Background: Varenicline tartrate is a new and selective agonist of the nicotinic acetylcholine receptor (nAChR). This systematic review and meta-analysis aimed to determine varenicline efficacy in smoking cessation among hospitalized patients. Methods: We looked through worldwide databases such as Web of Science, Embase, PubMed, Cochrane, and Scopus. Relevant pieces of research published on varenicline efficacy on smoking cessation among hospitalized patients were discovered using proper keywords. The data were analyzed using Stata software version 14 and a random-effects model meta-analysis. Findings: Nine studies were eligible to be included in this study, with a total sample size of 2131. Generally, the point abstinence rate was significantly greater in the varenicline group than in the placebo group at weeks 12 (odds ratio [OR]=0.59; 95% CI: 053-0.65; P<0.001), 24 (OR=0.78; 95% CI: 0.72-0.84; P<0.001), and 52 (OR=0.86; 95% CI: 0.80-0.92; P<0.001). Furthermore, the continuous abstinence rate for weeks 4 (OR=0.70; 95% CI: 019-0.54; P=0.000), 12 (OR=0.26; 95% CI: 019-0.54; P<0.001), 24 (OR=0.32; 95% CI: 019-0.53; P<0.001), and 52 (OR=0.32; 95% CI: 019-0.54; P<0.001) was significantly greater in the varenicline group than in the placebo group. Conclusion: According to the high efficacy of varenicline in both short- and long-term smoking settings and considering the importance of smoking cessation in high-risk hospitalized patients, varenicline consumption could be considered as a main smoking cessation strategy in these patients.
Awareness and Attitude Towards Tobacco Products and Tobacco Industry and Perception about Government’s Role in Tobacco Control among the Adult Rural Population: A Cross-sectional Study in the Indian State of Bihar
Authors: Nanda Naik Bijaya , Rao UR Rajath , Verma Manisha , Kumar Nirala Santosh , Pandey Sanjay , M Singh C
Published: June 2024

Background: Attitudes and impressions toward the tobacco industry and tobacco products among the general public are important determinants for curbing the menace of the tobacco epidemic. Accordingly, this study aimed to assess the knowledge and perceptions about the tobacco industry and tobacco products and analyze attitudes towards social denormalization (SD) of tobacco use and tobacco industry denormalization (TID) among the rural population of Bihar, India. Methods: This community-based cross-sectional survey was conducted on 421 adults aged 18 to 65 years who were selected using multistage systematic random sampling in a rural area of Bihar State in India from January to March 2022. Results were presented as proportions and the factors associated with support for TID and SD were identified using the chi-square test and binary logistic regression. Findings: Out of 421 participants, 342 (81.2%) did not consider smokeless tobacco to be very dangerous. Nearly half (192, 45.6%) of the individuals believed that tobacco companies never tell the truth about the ill effects of tobacco use on health. Maximum, 345 (89.5%) also believed that the tobacco industry is responsible for adverse health effects of tobacco use and that the government should sue them. The prevalence of favorable attitudes toward TID and SD was found to be 55.1% [95% CI: 50.3% – 59.8%] and 38.2% [95% CI: 33.7% – 42.9%], respectively. Conclusion: One out of every two and one out of every three individuals showed favorable attitudes toward TID and SD, respectively. There is a need to inform and educate the public on the ill effects of tobacco and the deceptive strategies used by the tobacco industry to help them choose health over tobacco.
Investigating the Effect of Substance Desire and Child Abuse in Adolescent Suicide Attempt
Authors: Gheshlagi Farzad , Meamar Rokhsareh , Rastkerdar Fatemehalsadat , Akbari Jebeli Azadeh , Soleimanpour Ali , Haddad Shadi , Eizadi-Mood Nastaran
Published: June 2024

Background: This study aimed to investigate the impact of child abuse and substance desire on adolescent suicide. Methods: This cross-sectional analytical study was conducted on all adolescents aged 12 to 19 who attempted suicide in 2018 at Khorshid Hospital, Isfahan, Iran. A checklist of the patients’ demographic information, toxicological data, and 2 standard questionnaires, including substance desire (family, personal, social) and child abuse questionnaire (emotional abuse, physical abuse, and neglect abuse), were collected. The data were analyzed using SPSS version 15. Comparisons between the 2 groups were performed using t tests, chi-square tests, regression analysis, and crude model analysis. Odds ratio (OR) and 95% confidence interval were calculated based on logistic regression. Findings: A total of 196 teenagers were included in the study, with a mean age of 16.48±1.6 years. Out of these, 155 individuals (79.1%) were female, resulting in a female-to-male ratio of 3.78. There was a significant relationship between gender and alcohol consumption in the personal aspect, as well as between the history of psychiatric diseases and alcohol consumption in the physical aspect (P<0.005). The previous history of suicide was the only variable that showed significance in all aspects of both the substance desire and child abuse questionnaires. History of neglect abuse (OR: 1.2, 95% CI [1.07–1.41]; P=0.009) was a predictive factor for suicide attempt. However, being male (OR: 0.12, 95% CI [0.039–0.37], P=0.000), having no psychiatric history (OR: 0.23, 95% CI [0.10–0.52], P<0.001) and not consuming alcohol (OR 0.33, 95% CI 0.15–0.71, P=0.005) were identified as protective factors for attempted suicide. Conclusion: A public health strategy for suicide prevention includes implementing prevention strategies aimed at reducing risk factors, such as alcohol consumption and the risk of neglect abuse.
Investigating the Relationship of Childhood Traumas and Sexual Guilt with Sexual Addiction in Iranian Prostitutes
Authors: Ghazaei Maryam , Rafei Nayereh
Published: June 2024

Background: Prostitution is a social phenomenon, and its underlying factors require more scholarly attention. This study aimed to investigate the relationship of childhood traumas and sexual guilt with sexual addiction in Iranian prostitutes. Methods: This was a cross-sectional study conducted on prostitutes who visited a health promotion center in Khorasan Razavi province, Iran in 2020. A total of 100 women agreed to participate in the study. Data collection tools included the Sexual Addiction Screening Test (SAST), Mosher Sex-Guilt Scale, and Childhood Trauma Questionnaire (CTQ). Data were analyzed using Pearson’s correlation coefficient and multiple regression analysis. Findings: The age of the participants ranged from 23 to 42, with a mean age of 33.54±8.9 years. About 40% of the participants were divorced, 13% were married, 27% were single, and 10% were widows. The findings indicated that 84% of the prostitutes met the criteria for sexual addiction according to SAST. Emotional abuse (r=0.41, P<0.001), physical abuse (r=0.32, P<0.001), sexual abuse (r=0.33, P<0.001), emotional neglect (r=0.52, P<0.001), and physical neglect (r=0.37, P<0.001) had a positive and significant relationship with sexual addiction in prostitutes. There was no correlation between sexual guilt and sexual addiction (r=0.13, P=0.09). Furthermore, the linear regression results showed that emotional neglect was the only variable positively associated with sexual addiction (β=0.5, P<0.001). Conclusion: The findings of this study suggested that childhood traumas can predict sexual addiction in female prostitutes.
The Role of Orexin Receptor Antagonists in Inhibiting Drug Addiction: A Review Article
Authors: Esmaili-Shahzade-Ali-Akbari Peyman , Ghaderi Amir , Sadeghi Atena , Nejat Fatemeh , Mehramiz Alireza
Published: June 2024

The orexinergic system and its receptors are involved in many physiological processes. Their functions in energy homeostasis, arousal, cognition, stress processing, endocrine functions, and pain modulation have been investigated. Many studies have shown that the orexinergic system cooperates with the dopaminergic system in the addiction process. Emerging evidence suggests that the orexinergic system can be effective in the induction of drug dependence and tolerance. Therefore, several researches have been conducted on the effect of orexin receptor (OXR) antagonists on reducing tolerance and dependence caused by drug abuse. Due to the significant growth of the studies on the orexinergic system, the current literature was conducted to collect the findings of previous studies on orexin and its receptors in the induction of drug addiction. In addition, cellular and molecular mechanisms of the possible role of orexin in drug tolerance and dependence are discussed. The findings indicate that the administration of OXR antagonists reduces drug dependence. OXR blockers seem to counteract the addictive effects of drugs through multiple mechanisms, such as preventing neuronal adaptation. This review proposes the potential clinical use of OXR antagonists in the treatment of drug dependence.
The Association Between Personality Traits and Substance Use Among Advanced Level Students in Western Province, Sri Lanka: A Cross-sectional Study
Authors: Charuni Thennakoon Janitha , Deva Adithiya Dilantha , Randika Jayamaha Akila
Published: June 2024

Background: While personality predominantly influences human cognition, emotion, and behavior, there is still an unresolved research gap concerning the association between personality and substance use within the Sri Lankan context. Methods: This descriptive cross-sectional study aimed to investigate the association between personality traits and substance use among advanced-level students aged over 18 in Western province, Sri Lanka, in 2023. Data collection was carried out using self-administered paper-pencil questionnaires. The study variables were measured using the brief version of the Big Five Personality Inventory and the Alcohol, Smoking, and Substance Involvement Questionnaire. Data analysis involved the use of the chi-square test and Spearman correlation. Findings: Of the 441 enrolled participants, 422 provided correct responses to the questionnaire. Among them, 154 (36.5%) reported substance use. The majority of students initiated substance use at the age of 17. The results reveal a significant association between the openness personality trait and substance use among advanced-level students in Western province. Additionally, there was a statistically significant positive correlation between the extroversion personality trait and amphetamine use among advanced-level students. Conclusion: The findings highlight a significant association between specific personality traits, particularly openness and extroversion, and substance use among advanced-level students in Western province, Sri Lanka. These results emphasize the significance of considering personality factors in understanding and addressing substance use behaviors among youth populations. Further research and targeted interventions are necessary to delve deeper into these associations and develop effective prevention and intervention strategies.
Dual-stage Acting Dendrimeric Nanoparticle for Deepened Chemotherapeutic Drug Delivery to Tumor Cells
Authors: Shahpouri Mohammad , Adili-Aghdam Mohammad Amin , Mahmudi Hossein , Ghiasvand Saeedeh , Dadashi Hamed , Salemi Aysan , Alimohammadvand Sajjad , Roshangar Leila , Barzegari Abolfazl , Jaymand Mehdi , Jahanban-Esfahlan Rana
Published: June 2024

Purpose: We report on the design of hypoxia-induced dual-stage acting dendrimeric nanoparticles (NPs) for selective delivery of two chemotherapeutic model drugs doxorubicin (DOX) and tirapazamin (TPZ) for deepened drug delivery into hypoxic tumors in vitro. Methods: PAMAM G5 dendrimers were crosslinked with a hypoxic azo linker, attached to a mPEG to form a detachable corona on the dendrimer surface (PAP NPs). NPs were characterized by Zeta sizer, transmission electron microscope (TEM), Fourier transforms infrared (FTIR) and drug release kinetics. The anti-cancer performance of PAPs was evaluated by numerous tests in 2D and 3D cultured MDA-MB-231 breast cancer cells. Results: MTT assay showed a significant difference between PAP and PAMAMG5 in terms of biocompatibility, and the effect of PAP@DOX was significantly greater than free DOX in hypoxic conditions. The results of DAPI and Annexin V-FITC/PI cell staining also confirmed uniform drug penetration as validated by induction of 90% cell apoptosis in spheroids and a high level of PAP@DOX-induced ROS generation under hypoxia conditions. Mechanistically, PAP@DOX significantly reduced the expression of mTOR, and Notch1, while the expression of Bax and Caspase3 was considerably unregulated, compared to the controls. Importantly, hypoxia-responsive disintegration and hypoxia-induced activation of HAP drug were synergized to promote deep and homogenous HAP distribution in whole microtumor regions to efficiently eliminate residual tumor cells. Conclusion: Our results indicate the safety and high therapeutic potential of PAP system for targeted drug delivery of chemotherapeutics in particular HAPs which show maximum anti-cancer activity against hypoxic solid tumors.
Comparison of the healing process of xenografts with three different sources in critical-size bone defects: An in vivo study
Authors: Amid Reza , Kadkhodazadeh Mahdi , Kheiri Aida , Esfandiari Shiva
Published: June 2024

Background. Xenograft bone substitutes can be obtained from different animals and processed using various methods. The present in vivo study evaluated bone regeneration after using three types of xenografts with different sources in critical-sized bone defects in rabbit calvaria. Methods. Four 8-mm defects were created in calvaria of 14 New Zealand and white male rabbits. Three out of four defects were filled with xenografts of bovine, camel, and ostrich sources. The fourth defect was left unfilled as the control group. Seven rabbits were sacrificed after eight weeks and seven others after 12 weeks. Micro-CT imaging and histologic evaluation were further performed on dissected calvarias. Results. After 8 and 12 weeks, the highest and lowest percentages of new bone formation were observed in the camel (27.71% and 41.92%) and control (11.33% and 15.96%) groups, respectively. In the case of residual material, the ostrich group had the most value after eight weeks (53%), while after 12 weeks, it was highest in the camel group (37%). Micro-CT findings were consistent with histologic results. Conclusion. Although all three xenografts can be good choices for treating bone defects, camel-sourced xenograft seemed to be better than the other two groups. The origin and processing procedures of xenografts affected their final characteristics, which should be considered for clinical use.
Effect of conventional cigarettes and e-cigarettes on salivary biomarkers: A systematic review
Authors: Dolatabadi Amirmohammad , Noori Faranak , Raee Amir
Published: June 2024

Background. E-cigarette consumption is increasing, and like conventional smoking, it can cause some harmful effects. This systematic review compared the effect of conventional cigarettes and e-cigarettes on salivary biomarkers. Methods. The search strategies included electronic databases (Medline/PubMed, Scopus, EMBASE) and related journals up to May 2023. A qualitative assessment was performed on data extracted from the included studies. Seven studies were included in this systematic review (number of patients=563). Results. Eleven biomarkers were assessed and compared between e-cigarette and conventional cigarette smokers. The data showed that the different effects of electronic and conventional cigarettes on the level of these biomarkers were not achievable. Due to the heterogeneity of the studies (I2 statistic>90%), performing a meta-analysis was impossible. Even after a sub-group classification, homogeneous data were not achieved. Conclusion. The current data do not provide evidence of obtainable outcomes between conventional cigarettes and e-cigarettes on salivary biomarkers.
Immediate full-arch fixed rehabilitation of a narrow mandible with newly conceived connection system implants: A case report
Authors: Pellegrino Gerardo , Zaccheroni Zoran , Lizio Giuseppe
Published: June 2024

Rehabilitating thin jaws without reconstructive surgery entails using narrow implants. The proposed treatment adopted an innovative implant system, allowing the mini-screws to be parallel and immediately loaded. A mandible, wearing an overdenture, was functionalized contextually to the residual dental extraction and the placement of six 2.4-mm thick one-piece implants. Low-profile intermediate abutments, the LEMs, able to rotate over the spherical heads of the fixtures, were connected after suturing, oriented, and blocked in a mutual parallel position. The copings, engaging with a tapered juncture of the LEMs, resulted in their alignment to be intraorally wedged together. The provisional superstructure enclosed the copings and was immediately connected to the implants, and the definitive prosthesis was delivered after three months. No clinical signs of peri-implantitis or radiographically evident bone loss were recorded after a two-year follow-up without any prosthetic complication. No cases have been published regarding mini-implants bearing fixed prosthesis rehabilitation.
Comparative assessment of the physical structure of antler and bovine bone substitutes: An in vitro study
Authors: Mahboubian Mohammad Hossein , Kadkhodazadeh Mahdi , Amid Reza , Moscowchi Anahita
Published: June 2024

Background. The use of bone graft materials has significantly increased. Given the inherent variations in structure and functionality between different grafting materials, this evaluated and compared the physical attributes of antler and bovine femur bone substitutes. Methods. In the present in vitro investigation, the surface morphological architecture of the two bone substitutes with different origins was assessed through scanning electron microscopy. Furthermore, the Brunauer–Emmett–Teller (BET) technique was employed to measure the porosity, specific surface area (SSA), and pore morphology. Results. Scanning electron microscopy observations indicated that the surface of the bovine particles appeared smoother, while the antler particles exhibited a rougher surface texture. The BET analysis revealed that both samples exhibited identical pore morphology. The SSA was 15.974 m2 /g in the antler particles compared with 18.404 m2 /g in the bovine sample. The total porosity volume in the antler and bovine femur bone substitutes were 0.2172 cm3 /g and 0.2918 cm3 /g, respectively. Additionally, the antler particles had a porosity percentage of 40%, whereas the bovine femur bone substitute showed a porosity percentage of 43.5%. Conclusion. Based on the results of this study, it seems that the two samples of bone grafting materials have comparable physical structures.
A comparative investigation of therapeutic effects of rose and lavender aromatherapy on hemodynamic symptoms of recently diagnosed diabetic patients: A single-blind randomized cross-over controlled clinical trial
Authors: Yousefi Pooneh , Hosseini Teshnizi Saeed , Faghih Aref , Taklif Mohammad Hossein
Published: June 2024

Introduction: Diabetes is a chronic and widespread problem with broad effects on human physiological systems, including significant impacts on hemodynamic symptoms, which can significantly affect the patient’s recovery process and quality of life. This study was conducted to compare the effects of rose and lavender aromatherapy on hemodynamic symptoms in patients with a recent diabetes diagnosis. Methods: In this cross-over controlled clinical trial study, three distinct groups were employed: two experimental groups (aromatherapy with rose and lavender) and a single control group. Pre-test and post-test assessments were conducted before and after the intervention on a total of 45 diabetic patients in 2022 at the Hormoz Clinic in Bandar Abbas. The interventions occurred over three sessions, with each patient receiving different treatments during different periods (first, second, and third stages). A one-week washout period was implemented between the stages to mitigate any potential carryover effects. Before initiating the interventions, demographic variable questionnaires and hemodynamic symptoms (systolic and diastolic blood pressure, and pulse rate) were documented both before and after the interventions. Data were analyzed using Stata version 14.0 and SPSS version 26 statistical software. Results: The mean diastolic blood pressure (P=0.459), systolic blood pressure (P=0.908), and pulse rate (P=0.125) did not differ significantly between the three groups before the intervention. However, there were significant differences in mean diastolic blood pressure (P<0.001) and mean pulse rate (P<0.001) in the post-intervention of the three groups. Conclusion: Aromatherapy treatments using rose and lavender essential oils can contribute to the stabilization of some Hemodynamic Symptoms.
Comparison of autologous blood Injection versus methylprednisolone Injection in Treatment of fasciitis plantar: a single-blind clinical trial
Authors: Bahram Masoud , Baghianimoghadam Behnam , Shirafkan Hoda , Kamali Ahangar Sekineh , Khoshbakht Shahriyar
Published: June 2024

Background. Various methods have been proposed to treat plantar fasciitis. Among these, autologous blood transfusion has been discussed and investigated in the past few years, the findings indicate its effects in the medium term, and in some studies, better results were observed compared to corticosteroids. This study was conducted with the aim of comparing the effect of two therapeutic methods of local injection of autologous blood and corticosteroid with the control group in the treatment of plantar fasciitis. Methods. In this prospective study that took place in Shahid Beheshti Hospital, Babol, during 2020–2021, 90 plantar fasciitis patients were examined in two treatment groups by corticosteroid injection or autologous blood. Their levels of pain and satisfaction were recorded during three and six months by the visual analog scale (VAS) and the Roles and Maudsley Scale (RMS). The data were described and analyzed by SPSS-22 using descriptive indices and statistical analysis tests at a significance level of 0.05. Results. There was no significant difference in pain and satisfaction during the third month of steroid and autologous blood transfusions. However, in the sixth month, the patients in the autologous blood group had significantly less pain than those in the steroid group (P= 0.001), and their level of satisfaction was significantly higher than that of patients in the steroid injection group (P= 0.018). The mean pain intensity based on VAS in six months was 5.40 ± 1.37 and 3.76 ± 1.87 in the steroid and autologous blood groups, respectively (P< 0.001). Based on the Wilcoxon test, the VAS score increased significantly in the steroid group in the sixth month compared to the third month (P= 0.011), while it decreased in the autologous blood group (P< 0.001). Conclusion. Based on the findings, autologous blood injection in plantar fasciitis over six months had significant pain-reducing effects and satisfaction versus corticosteroid injection. However, after three months, these effects were not significant compared to corticosteroids. Practical Implications. Based on the findings, autologous blood injection in plantar fasciitis over six months had significant pain-reducing effects and satisfaction versus corticosteroid injection. However, after three months, these effects were not significant compared to corticosteroids.
A comparative study of the effectiveness of Non-computer and Computer-based Cognitive Rehabilitation Interventions on Auditory/Visual Working Memory of Stroke Patients
Authors: Alivandi Vafa Marziyeh , Shalchi Behzad , Farhodi Mehdi , Nazari Mohamad Ali , Abidi Horolar Leyla
Published: June 2024

Background. Given the fact that there is contradictory evidence regarding the effectiveness of computerized cognitive rehabilitation interventions, the present study intended to compare the potential effects of non-computer and computer-based cognitive rehabilitation interventions on the memory of stroke patients in Tabriz. Methods. To this end, we conducted a quasi-experimental study with a pretest-posttest control group design. The population of the study included individuals who were admitted to a hospital in Tabriz, Iran, for the treatment of stroke. After identifying patients who met the inclusion criteria on the base of purposive sampling, 45 stroke patients were randomly selected and assigned to two experimental groups (15 in the computer-based group and 15 in the non-computer group) and one control group (15 in the waiting list). To measure the dependent variables of the research, Wechsler’s Digit Span subscale and Folstein’s MMSE were used. The cognitive rehabilitation therapy was performed three times a week for 7 weeks for the non-computer experimental group. The computer-based rehabilitation intervention using Captain’s Log software was delivered during the same period. Results. The results show that both computer-based and non-computer cognitive rehabilitation interventions are equally effective in improving working memory (visual and auditory) of stroke patients. Conclusion. It can be concluded that the unsubstantiated orientation towards the quality and quantity of using new computer-based interventions is not desirable and that the potential of both computer and non-computer interventions should be used to improve the memory of stroke patients. Practical Implications. Based on the findings, specialists can use the potential of both non-computer and computer-based cognitive rehabilitation interventions in improving auditory/visual working memory function of patients with stroke.