bluuebunny/crossref_metadata_2025 huggingface dataset:
Features and Patterns of Functioning of Financial resources of Digital companies
Authors: Skokov R. Yu.
Published: November 2022

The relevanceof the study is due to the monopolization of the markets for goods and services by transnational digital companies.

The objectof the study is the finances of the two world’s largest digital and oil companies — Meta Platforms Inc. and Saudi Arabian Oil Company.

The subjectof the study is economic relations in the functioning and regulation of the economic behavior of traditional and digital companies in the context of the digital transformation of existing markets and the creation of new markets for digital goods.

The purposeof the study is to identify the features of development and patterns of functioning of the system of financial resources of digital companies.

The methodological baseof the study is based on the financial analysis of a digital and oil company, including a comparative analysis of market capitalization, financial results and balance sheets (revenue, net income, assets, liabilities), financial condition, liquidity, profitability, and a comprehensive assessment of performance. It has been established that five manufacturers of digital goods by capitalization in 2020–2022 were among the 12 world leaders and significantly strengthened their positions against the backdrop of traditional business during the pandemic. The size of the largest oil company in 2014–2020 was more significant than that of a digital company, but the gap in dynamics decreased from 7 times in 2017 to 3 times in 2020. At the same time, the liquidity of the balance sheet of a digital organization is 4–7 times higher than that of an oil company, the financial condition is absolutely stable, and independence from external creditors is the highest. The oil company’s cost-effectiveness indicators are still higher, as the digital one invests in network development and attracting new users. However, in dynamics, the oil company’s profitability has halved over the past four years.

The author comes to theconclusionthat in the medium term, a digital company is projected to outperform an oil company in terms of size and efficiency. For the first time in international and domestic science, it is proposed to increase normative values of liquidity and financial stability indicators of a digital company by 4–7 times higher compared to traditional organizations, which determines thescientific noveltyof the study.
Cryptocurrencies vs Central Banks' Digital Currencies: The Role of Financial Literacy
Authors: Krylova L. V. , Lukashenko I. V.
Published: November 2022

A bifurcation point has arisen in the transformation of the global monetary and financial system, associated with its further digital transformation: will it be based on private digital currencies like Bitcoin, or on the basis of central bank digital currencies (CBDC)? To a large extent, this depends on the willingness of economic agents to use virtual currencies.

The purpose of the study is to explore the factors determining the attitude of economic agents to digital currencies and the impact of financial literacy on using these instruments as an investment object and means of payment.

The authors use the following research methods: content analysis, retrospective analysis, methods of comparative cross-country analysis, and empirical research in the form of an online survey of graduate financial students. This study is one of the first to reveal differences in the assessment of their knowledge and readiness to use digital currencies of financial and non-financial students, as well as to confirm an adequate assessment of the risks and opportunities of different types of virtual currencies if students have financial knowledge. The research shows that the situation with the decisionmaking of economic agents on the use of cryptocurrencies and the CBDC differs: in the first case, the initiative comes from the economic agents themselves, who make decisions at their own peril and risk; in the second case, economic agents are confronted with the fact of the existence of the CBDC and the need to use them.

The authors conclude that the population’s low financial and digital literacy can create a mental barrier to the use of CBDC, complicating their implementation in national monetary systems. The lack of financial literacy leads to an exaggeration of their knowledge by participants in the cryptocurrency market.
Commercialization of Public Finance Management: Modern realities and Organizational and legal Modernization
Authors: Lapina M. A. , Zav’yalov M. M. , Gurinovich A. G.
Published: November 2022

The subject of the research is a substantive study of the modern realities of commercialization of public finance management and the possibility of its organizational and legal modernization.

The purpose of the research is to establish the current state of commercialization of public finance management and to identify emerging problems in managing the liquidity and debt of the state, together with the possibilities and ways of leveling them and hedging risks through the organizational and legal modernization of public finance management.

The relevance of scientific research and its scientific novelty are based on the absence in the Russian Federation of fundamental research on the current state of public finance management and its commercialization factors. The domestic scientific and practical literature touches on certain aspects of the issue under study, which does not allow us to establish cause-and-effect relationships of problems arising in the course of public finance management.

The research is based on general scientific and special methods containing elements of comparative jurisprudence, system analysis, structural and functional approach, as well as a comprehensive and complete study and critical analysis of domestic and foreign fundamental scientific research, containing a number of studies in the field of legal regulation, public administration, econometrics, and macroeconomic forecasting. The collection and analysis of the material for the preparation of scientific research was carried out by a scientific group taking into account the quantitative and qualitative indicators of the authors’ citations, as well as the significance of their individual research.

The authors conclude about the need to hedge risks when exercising the authority to manage liquidity and debt as integral elements of macroeconomic policy, with the elimination of the fragmented organizational structure of the authorities. Based on international experience, a number of authors’ recommendations have been developed to create, within the framework of organizational and legal modernization, a unified effective commercialized public finance management system with the establishment of promising potential development options to ensure the achievement of the state’s sustainable development goals stipulated by national projects.
Analysis of Changes in the Soundness of Korean Stocks after Capital Market Opening: Focusing on Role and Identification of Long-term Equilibrium Variables
Authors: Kim Yun-Yeong
Published: November 2022

This study examines and evaluates changes in the soundness of Korean stock prices by classifying the financial and global financial crises after the 1990s, when the capital market was first opened. The criteria for judging soundness include whether stock prices are determined by long-term equilibrium variables, whether there is a trend among non-long-term equilibrium variables, and whether long-term equilibrium variables of overseas stocks are identified during the Korean stock price determination process. Further, a co-integration test is performed using the VAR model which comprises the stock prices from Korea and the United States, and their long-term economic equilibrium variables. Furthermore, a transformation error correction model with a VAR type consisting of differences and cointegration errors in Korean stock prices is derived. Accordingly, the trend of long-term equilibrium variables is estimated using the Beveridge-Nelson decomposition of Korean stock prices. Furthermore, a test for its presence is performed. According to the empirical analysis conducted using monthly Korean data; the influence of the long-term equilibrium variable trend in the Korean economy tends to increase the stock prices following a financial crisis.
Do Korean Pension Guidelines Improve Firms’ Management Efficiency?
Authors: Ahn Ha Eun , Hong Jun Yeung
Published: November 2022

This study examines whether Korean pension guidelines that limit the payment of director show practical policy effectiveness by improving corporate management efficiency. Specifically, this study examines stickiness of pay to determine whether opportunistic executive payment existed in firms where executive pay was above 50% of articles of incorporation, before the announcement of the Korean pension guidelines. Further, we examine how executive pay stickiness has changed after the implementation of Korean pension guidelines to check whether they have been effective in improving corporate management efficiency. We use data from 2011 to 2019 and determine that, prior to the announcement of Korean pension guidelines, firms who paid above 50% of articles of incorporation showed higher executive payment stickiness. This suggests that these firms had a more opportunistic payment structure. However, this stickiness disappears after the announcement of Korean pension guidelines in 2020, suggesting that the Korean pension guidelines for executive pay show policy effectiveness. However, in 2020, the majority of decision-making within firms was affected by the global pandemic; therefore, there exists a need for additional research using a sample unaffected by the impact of the pandemic.
Cryptoasset Returns: Statistical Properties and Implications for Asset Allocations
Authors: Kim Hyemin , Kim Noolee
Published: November 2022

We examine Bitcoin returns’ statistical properties and check whether these properties are consistent with the well-known stylized facts of asset returns for the period from January 2019 to May 2022. We find that Bitcoin exhibits price behaviors that correspond well to all the stylized facts of asset returns examined in the analyses. We also examine the returns of Tesla stock, NASDAQ index, and S&P500 index for comparison and find that they generally conform to the stylized facts examined. However, Tesla stock does not exhibit an asymmetric volatility feature, and the two indices show significant autocorrelations in low order time lags, which are inconsistent with the well-known stylized facts of asset returns. Based on these findings, we discuss the possible implications of cryptoassets for asset allocation processes. Cryptoassets provide some potential utilities for asset allocations, but only with several simultaneous limitations.
We Refuse to Cope! The Vitruvian Nurse, the Code of Conduct, and Nurses’ Lived Knowledge
Authors: Smith Jamie , Willis Eva
Published: November 2022

We, as nurses, refuse to cope. In this editorial style piece we discuss the ongoing crisis in nursing and the ways in which this situation is being produced. We discuss the metaphors with which nursing is produced in the UK and US and how these metaphors produce an idealized version of nurses and nursing that is impossible. We situate this metaphor in critical posthuman theory by drawing comparisons to Braidotti’s (2013) understanding of the idealised human as an axiom of social production under advanced capitalist societies. We make comparisons of this idealized person with the idealized nurses that are captured in nursing codes of conduct and practice. We then suggest ways in which we can resist and diffract metaphors in nursing to produce affirmative futures.
Science’s Stories and Other Possible Grammars
Authors: Silver Jake
Published: November 2022

For ages, science has told divisive stories about the world, especially along racial lines: who is more human; who is fit to rule; who matters. And yet, science continues to enchant us, sustaining wonder within its mission to help us grasp and put into words the unknown. This review essay follows how three recent monographs that straddle STS and Black studies seize upon this seeming contradiction. I argue that they do so by cataloguing the elements of science’s stories: genres, beginnings, plotlines, grammars, characters, and endings. In so doing, these texts not only diagnose scientific racism, but they offer a horizon for telling different scientific stories. They gesture toward a science that reveals new arrangements of the physical world already in front of us. With their focus on relationality, insistent that the story of science entails humanity’s entwined and plural stories, these texts offer lucid and captivating templates for pursuing a decolonial study of science freed from differentiation, classification, opposition, and the hierarchies they architect.
Game Over: The Perils of Framing Feminist Game Design Pedagogy as Repair versus Transformation
Authors: Corron Amy , Rouse Rebecca
Published: November 2022

Drawing on the experience of a multiyear research project bringing transformative pedagogies to game design education, we provide a critical reflection on the lack of sustainability of the project. Upon examination, we see that some reasons behind this perceived failure are due to institutional systems of power that seek to neutralize transformative feminist pedagogy as performative repair, resulting in the maintenance of existing curricula. Instead of fully engaging with transformative pedagogies, these teaching and learning methods are used as tools to provide a cursory fulfillment of the deep need for social justice education in games. We examine the ways in which structures and systems continually devalue and de-resource pedagogical work, specifically pedagogies that are centered in feminist, anti-racist, and critical approaches, as well as our own complicity within these oppressive structures at times. We draw connections with relevant disciplinary perspectives on higher education, and conclude by offering a framework for understanding the pitfalls that can hamper work with transformative pedagogical aims, characterized by the types of labor used to maintain the status quo, as well as a set of recommendations for moving beyond the frame of repair to sustainably and radically disrupt dominant pedagogies in games and related disciplines.
Technologies of Quiescence: Measuring Biodiversity, “Intactness,” and Extractive Industry in Canada
Authors: Blacker Sarah
Published: November 2022

Debates over the environmental costs of industrial resource extraction in Alberta, Canada—home to a petrochemical industry that plays an outsize economic and political role—are reaching a fever pitch in response to government regulations on industry, data on climate change threats, and social movements pushing for environmental protection. Away from the news headlines, scientists are developing new metrics and models to calculate biodiversity loss and other outcomes of industrial environmental contamination. But these data are not only used to provide evidence of environmental harm. Practitioners of settler science like the Alberta Biodiversity Monitoring Institute employ such data in combination with the metaphor of environmental “intactness,” generating colonial mythologies of terra nullius anew, and enabling industrial extraction to continue. This paper theorizes a technology of settler colonial concealment. It shows how settler technologies of quiescence operate through the strategic use of scientific metrics, thereby concealing evidence of colonial harm and promoting a fiction of environmental “intactness” in a province that is home to one of the most environmentally destructive industries in the world.
THREEDIMENSIONAL STRUCTURE OF THE PENTAPEPTIDE MOLECULE ARG-GLU-ARG-GLY-PRO
Authors: Ismailova L. , Abbasli R. , Akhmedov N.
Published: November 2022

It seems relevant to carry out structural and functional studies of glyprolines and their synthetic analogues on model systems using theoretical research methods. Glyprolines are a family of short peptides whose amino acid sequences contain residues of proline and glycine. Currently their mechanisms of action are poorly understood. Great interest in their structure is caused by the possibility of creating new drugs that are the human body’s own reserve. Glyproline molecules are stable and eddicient. Using the method of molecular mechanics, the spatial structure and conformational properties of the glyproline pentapeptide molecule Arg-Glu-Arg-Gly-Pro were determined. The potential energy of the molecule was estimated as the sum of non-valent, electrostatic, torsion interactions and the energy of hydrogen bonds. 9 low-energy conformations were found for glyproline pentapeptide, the values of structure the dihedral angles of the main and side chains, and the energy of intra-and inter-residue interactions was estimated. It is revealed that low energy conformations of this molecule have the half-folded type of backbone. The side chains of the Arg and Glu amino acids in low-energy conformations carry out effective interactions and are conformationally labile amino acids, they bring together the regions of the main chain and the side chains of the amino acids included in the pentapeptide.
NANOSECOND MICROWAVE PULSES AFFECT STEM CELL PROLIFERATION RATE
Authors: Bolshakov Mikhail , Samoylova Anna , Gostyukhina Alyona , Doroshenko Olga , Kutenkov Oleg , Zaytsev Konstantin , Rostov Vladislav
Published: November 2022

On 17 cultures of stem cells (SK) isolated from the femur of laboratory rats «Wistar», the change in the rate of cell proliferation in vitro after irradiation with 4000 nanosecond microwave pulses with a pPFD of 140 and 1500 W/cm2 at pulse repetition rates of 8 and 13 Hz was experimentally studied. It has been established that exposure to nanosecond RPMR with both intensities affects the rate of proliferation SK. After exposure to 4000 RPMR pulses with 140 and 1500 W/cm2 pPFD and a pulse repetition rate of

8 Hz, inhibition of cell proliferation was observed relative to the control group. After exposure to a pulse repetition rate of 13 Hz at the same intensities, stimulation of proliferation took place, as a result of which the number of stem cells in the studied cultures increased. The main revealed pattern is the dependence of the effect (on the pulse repetition rate and, in part, on the intensity). Understanding the patterns will allow choosing and using the most optimal mode of exposure to achieve the desired result, and knowledge of the primary mechanism will make it possible to enhance or weaken the effect, in particular, the combined effect of RPMR with other factors.
THE EFFECT OF USING E-MARKETING TOOLS IN ACTIVATING SALES IN HOTELS: A FIELD STUDY IN FIVE-STAR HOTELS IN THE JORDANIAN CAPITAL – AMMAN
Authors: Abu Rokbeh Alanoud Amer Saleem
Published: November 2022

The purpose of this study is to look at the effect of employing E-Marketing techniques on activating sales in Amman city hotels. The quantitative technique was utilized in the investigation, with data collected using questionnaires. (500) questionnaires were delivered to guests at (13) Jordanian five-star hotels in Amman. (484) of the (500) questionnaires were recovered, while (16) were eliminated due to excessive missing data. According to the study, adopting E-Marketing tools such as: (the hotel website, hotel blog, hotel social media, and hotel e-mail) has a substantial influence on sales promotion such as: (trade contest, coupons, and rebates). Finally, the study suggests that hotels in Amman continue to implement an E-Marketing policy, activate trade promotion electronically, and promote their services through all electronic channels, particularly social media sites.
Analisis Gaya Bahasa Novel Badai Matahari Andalusia Karya Hary El-Parsia
Authors: Julia Maulida Nela , Intiana Siti Rohana Hariana , Khairussibyan Muh.
Published: November 2022

Karya sastra merupakan ciptaan untuk tujuan estetika. Rene Wellek dan Austin Warren (1989:3) mengatakan sastra adalah suatu kegiatan kreatif dalam sebuah karya seni. Dalam menyampaikan imajinasi dalam bentuk karya sastra, pengarang menggunakan bahasa sebagai mediumnya. Adapun salah satu ciri atau sifat bahasa sastra adalah penggunaan gaya bahasa. Gaya bahasa digunakan oleh pengarang untuk memperindah tulisannya. Penggunaan gaya bahasa dalam sebuah karya sastra bertujuan untuk memperoleh efek estetis atau keindahan, maka dari itu pengarang berusaha untuk menambahkan sebuah gaya bahasa di dalam sebuah karyanya sehingga pembaca akan lebih tertarik untuk membacanya. Penelitian ini bertujuan untuk mendekripsikan bagaimanakah makna gaya bahasa perumpamaan, personifikasi, alegori, hiperbola, paradoks, dan oksimoron dalam novel Badai Matahari Andalusia karya Hary El-Parsia. Metode pengumpulan data pada penelitian ini menggunakan teknik baca dan catat. Berdasarkan hasil analisis, Pada penelitian ini ditemukan gaya bahasa kiasan dan retoris dalam novel Badai Matahari Andalusia karya Hary El-Parsia. Adapun data yang ditemukan pada a) gaya bahasa kiasan meliputi perumpamaan 46, personifikasi 34, dan alegori 7; b) gaya bahasa retoris meliputi hiperbola 51, paradoks 10, dan oksimoron 7. Pada novel Badai Matahari Andalusia karya Hary El-Parsia didominasi dengan penggunaan gaya bahasa kiasan yaitu, perumpamaan dengan  46 kutipan, sedangkan gaya bahasa retoris didominasi dengan penggunaan hiperbola 51 kutipan. Pemakaian gaya bahasa dalam novel Badai Matahari Andalusia melalui kalimat atau ungkapan-ungkapan sebagai sarana untuk menarik minat pembaca. Dalam memahami makna penggunaan gaya bahasa dalam novel Badai Matahari Andalusia perlunya pemahaman dan ketelitian pembaca.
Perbandingan Hasil Point of Care Testing (POCT) Asam Urat dengan Chemistry Analyzer
Authors: Akhzami Dewi Rabiatul , Rizki Mohammad , Setyorini Rika Hastuti
Published: November 2022

Latar belakang: Hiperurisemia merupakan peningkatan kadar asam urat dalam darah. Pada dekade terakhir prevalensi hiperurisemia cenderung meningkat di seluruh dunia. Oleh karena itu, dibutuhkan pemeriksaan laboratorium untuk mengetahui kadar asam urat serum. Alat yang telah digunakan sebagai alat standar dalam pemeriksaan laboratorium adalah chemistry analyzer. Seiring perkembangan teknologi dan pengetahuan, terdapat alat lain yang dapat digunakan yaitu point of care testing (POCT).

Tujuan: Untuk mengetahui perbedaan hasil antara point of care testing (POCT) asam urat dengan chemistry analyzer.

Metode: Penelitian dengan desain studi perbandingan dengan metode potong lintang (cross-sectional). Pengambilan sampel dilakukan dengan tehnik consecutive random sampling dan memenuhi kriteria inklusi (n=42). Selanjutnya dilakukan pengambilan sampel darah dari vena antecubital, kemudian dilakukan pemeriksaan dengan point of care testing (POCT) dan chemistry analyzer. Uji statistika yang digunakan yaitu uji Wilcoxon untuk mengetahui perbedaan hasil pemeriksaan asam urat antara alat POCT dan chemistry analyzer.

Hasil: Kadar asam urat serum yang diperiksa dengan point of care testing (POCT) dengan strip/stik berkisar antara 3,1-11,1 mg/dl dengan nilai tengah 5,65 mg/dl dan rentang antar kuartil (interquartile range [IQR]) 7,4 mg/dl sedangkan kadar asam urat serum responden yang diperiksa dengan menggunakan chemistry analyzer berkisar antara 3,1-12,3 mg/dl dengan nilai tengah 5,45 mg/dl dan rentang antar kuartil (interquartile range [IQR]) 7,1 mg/dl. Tidak terdapat perbedaan yang signifikan antara pemeriksaan asam urat dengan POCT dan chemistry analyzer (p=0,7460; uji Wilcoxon).

Kesimpulan: Tidak terdapat perbedaan hasil antara point of care testing (POCT) asam urat dengan chemistry analyzer.
Perbandingan Lama Analgesia Bupivakain Hiperbarik + Morfin Intratekal dengan Bupivakain Hiperbarik + NaCl Intratekal pada Pasien yang Menjalani Operasi dengan Anestesi Spinal
Authors: Mardani Imam , Kresnoadi Erwin , Setyorini Rika Hastuti
Published: November 2022

Latar Belakang : Nyeri pasca operasi merupakan salah satu faktor yang mempengaruhi kenyamanan pada pasien yang sudah menjalani operasi. Penggunaan anestesi spinal termasuk salah satu teknik anestesi yang dapat dipilih untuk mengurangi nyeri pasca operasi. Obat yang dapat digunakan sebagai agen anestesi adalah kombinasi bupivakain dan morfin. Penelitian ini bertujuan untuk mengetahui efektifitas penambahan morfin terhadap bupikain hiperbarik untuk memperpanjang durasi analgesia.

Metode : Penelitian ini bersifat analitik deskriptik dengan menggunakan data sekunder. Penelitian dilakukan terhadap 48 pasien dengan status fisik ASA I-II yang terbagi dalam dua kelompok. Kelompok A (perlakuan) mendapat bupivakain 0,5% 12,5 mg hiperbarik ditambah morfin 0,1 mg intratekal dan kelompok B (kontrol) mendapat bupivakain 0,5% 12,5 mg hiperbarik ditambah NaCl 0,9% 0,1 cc intratekal. Penilaian lama analgesia dilakukan dari awal pemberian obat sampai terjadinya regresi 2 segmen. Analisis statistik pada penelitian ini menggunakan independent t-test dan uji Mann whitney

Hasil : hasil penelitian ini didapatkan bahwa lama analgesia kelompok perlakuan lebih panjang dibandingkan dengan kelompok kontrol dengan perbedaan bermakna.

Simpulan : simpulan dari penelitian ini adalah lama analgesia bupikain 0,5% 12,5 mg hiperbarik ditambah morfin 0,1 mg lebih lama dibandingkan bupivakain 0,5% 12,5 mg hiperbarik ditambah Nacl 0,9% 0,1 cc.
Efektivitas Ekstrak Buah Ara (Ficus Glomerata ROXB.) sebagai Antidiabetes pada Mencit Balb/C yang diinduksi Aloksan
Authors: Dewi Citrangganai Prajnya , Anggoro Joko , Ekawanti Ardiana
Published: November 2022

Latar belakang: Buah ara (Ficus glomerata Roxb.) merupakan salah satu buah dengan kandungan antioksidan yang tinggi dan memiliki potensi untuk menurunkan kadar glukosa darah. Penelitian ini dilakukan untuk mengetahui pengaruh pemberian ekstrak buah ara terhadap kadar glukosa darah pada mencit BALB/c yang diinduksi aloksan.

Metode: Penelitian ini merupakan studi eksperimental dengan rancangan pre-post test control group, yang menggunakan 35 ekor mencit BALB/c yang terbagi dalam 5 kelompok. Tiga kelompok (P1, P2, P3) merupakan kelompok perlakuan yang diinduksi aloksan dan diberi ekstrak buah ara dengan dosis yang berbeda yaitu 100 mg/kgBB, 300 mg/kgBB, dan 500 mg/kgBB. Kelompok empat sebagai kontrol negatif (K-) diinduksi aloksan dan diberi akuades serta kelompok lima sebagai kontrol positif (K+) diinduksi aloksan dan diberi glibenklamid. Setiap kelompok mendapatkan perlakuan masing-masing selama 14 hari dan dilakukan pengambilan sampel pada hari ke 15.

Hasil: Uji Friedman yang dilanjutkan dengan post hoc uji Wilcoxon menunjukkan terdapat perbedaan kadar glukosa darah sebelum dan sesudah perlakuan yang bermakna (p<0,05) pada kelompok P1, P2, P3 dan K- dengan nilai signifikansi masing-masing sebesar 0,046, 0,028, 0,018 dan 0,046. Uji beda untuk membandingkan hasil akhir kadar glukosa darah pada masing-masing kelompok menggunakan uji Mann Whitney menunjukkan hanya kelompok P2 dan P3 yang memiliki pengaruh yang bermakna terhadap penurunan kadar glukosa darah dengan nilai signifikansi sebesar 0,003 dan 0,004.

Kesimpulan: Pemberian ekstrak buah ara (Ficus glomerata Roxb.) memiliki pengaruh yang bermakna terhadap penurunan kadar glukosa darah pada mencit BALB/c yang diinduksi aloksan.
Pengaruh Pemberian Ekstrak Anggur Hitam (Vitis vinifera) terhadap Kadar Trigliserida Darah pada Tikus Wistar (Rattus norvegicus) Jantan yang Diinduksi Hiperkolesterol
Authors: Hapsari Dita Nur , Lestarini Ima Arum , Priyambodo Seto
Published: November 2022

Latar Belakang: Di Indonesia, sekitar 7,2% penduduk menderita Penyakit Jantung Koroner. Penyakit Jantung Koroner adalah penyakit jantung yang disebabkan karena penyempitan arteri koronaria akibat proses aterosklerosis. Faktor resiko penyebab aterosklerosis antara lain hiperlipidemia, kebiasaan merokok, diebetes millitus, kurangnya aktifitas, dan stress. Hiperlipidemia merupakan kenaikan kadar kolesterol, trigliserida ataupun keduanya. Aterosklerosis dapat dicegah dengan mengubah pola hidup dengan memperhatikan pola makan yang sehat salah satunya dengan buah anggur hitam. Kadar flavonoid pada anggur hitam meningkatkan aktivitas lipoprotein lipase sehingga berpengaruh terhadap kadar trigliserida serum.

Metode: Desain penelitian ini adalah Post Test Only Control Group Design. Besar sampel penelitian adalah 24 ekor, dibagi menjadi 6 kelompok yaitu kelompok normal (K1), kelompok yang diinduksi hiperkolesterol 28 hari (K2), kelompok yang diinduksi simvastatin 14 hari (K3), kelompok perlakuan dengan dosis anggur hitam selama 14 hari masing-masing  200 mg/200 grBB/hari (P1), 400 mg/200 grBB/hari (P2), dan 800 mg/ 200grBB/hari (P3).Selanjutnya data akan dianalisa dengan uji One-way ANOVA.

Hasil: Nilai rerata kelompok normal (K1) adalah 42,8 Â± 24,7 kelompok K2 adalah 59,3 Â± 30,4  gr/dl , K3 adalah 63,0 Â± 23,2 gr/dl. Nilai kelompok perlakuan dosis berturut-turut P1 adalah 90,3 Â± 30,8 gr/dl, P2 adalah 55,3 Â± 41 gr/dl, dan P3 adalah 50,3 Â± 14,7 gr/dl. Dari uji statistik menggunakan One-way ANOVA didapatkan nilai p 0,311 (p>0,05) yang dapat diartikan bahwa tidak ada penurunan kadar trigliserida secara bermakna.

Simpulan: Pemberian ekstrak anggur hitam (Vitis vinifera. L) tidak berpengaruh secara bermakna terhadap perbedaan rerata kadar trigliserida darah tikus putih jantan (Rattus novergicus) yang diinduksi hiperkolesterol
Uji Diabetes Secara Non-Invasif Berbasis Kadar Asam Sialat Saliva
Authors: Harlan Muhammad Fauzan , Geriputri Ni Nyoman , Asmara I Gede Yasa
Published: November 2022

Latar Belakang: Diabetes mellitus (DM) merupakan kelainan metabolisme karbohidrat yang mempengaruhi banyak sistem, ditandai dengan hiperglikemia dan glukosauria akibat insufisiensi sekresi insulin absolut atau relatif, atau resistensi insulin pada target jaringan. Diabetes menyebabkan mortalitas dan morbiditas terutama karena komplikasinya. Self-Monitoring of Blood Glucose (SMBG) merupakan suatu terobosan besar dalam penanganan diabetes karena pasien dapat menentukan kadar glukosa mereka selama kehidupan sehari-hari.

Tujuan: Penelitian ini dilakukan untuk mengkaji kemungkinan penggunaan kadar asam sialat saliva sebagai bahan uji non-invasif pada penderita diabetes melitus.

Metode: Penelitian ini merupakan penelitian komparatif. Sampel yang digunakan adalah saliva yang berasal dari 20 orang dan terbagi menjadi 2 kelompok, yaitu kelompok orang dengan diabetes (D), dan kelompok orang normal/non-DM (N). Saliva yang terkumpul disentrifugasi dengan 8000 rpm. Hasil sentrifugasi berupa supernatan diambil sebanyak 50 Î¼l dan ditambahkan 100 Î¼l reagen Ninhydrin. Hasil campuran dipanaskan pada suhu 60Â°C dan dibaca dengan spektrofotometer pada 570 nm. Uji statistik dilakukan dengan menggunakan Independent Sample T-test

Hasil: Rerata kadar asam sialat saliva pada kelompok D dan N masing-masing  4.579 Â± 1.113 dan 1.204 Â± 0.549. Berdasarkan data tersebut, secara statistik terlihat perbedan kadar asam sialat saliva yang bermakna ( p<0,05).

Kesimpulan: Terjadi peningkatan kadar asam sialat saliva yang bermakna pada penderita diabetes melitus bila dibandingkan dengan kadar asam sialat saliva pada orang tanpa diabetes, hal ini menunjukan konsentrasi DNA saliva dapat digunakan sebagai bahan uji non-invasif pada penderita diabetes melitus.
Fraktur Monteggia: Tantangan Klinisi dalam Menghadapi Fraktur Dislokasi yang Sering Misdiagnosis
Authors: Alaydrus M. Mukaddam
Published: November 2022

Fraktur Monteggia merupakan salah satu jenis fraktur yang terjadi pada regio antebrachii. Fraktur Monteggia adalah fraktur pada os ulna bagian proksimal disertai dislokasi dari caput radii pada proximal radioulnar joint (PRUJ). Kasus ini sering misdiagnosis meskipun telah dilakukan pemeriksaan X-Ray terutama dalam mengenali dislokasi atau subluksasi dari caput radii. Insidensi kasus tersebut terjadi 13% dari seluruh kasus fraktur pada regio antebrachii. Karena letaknya yang diibaratkan sebagai dua kerucut (cones) yang berdampingan dengan satu sama lain saling menunjuk pada arah yang berlawanan, maka perlu diingat bahwa segala cedera yang terjadi pada regio antebrachii menimbulkan efek pada os radius dan ulna. Mekanisme trauma yang paling sering adalah terjatuh dengan tangan menopang tubuh pada posisi hiperekstensi. Berdasarkan klasifikasi Bado, fraktur Monteggia dibagi menjadi 4 tipe. Gejala klinis yang nampak antara lain bengkak pada siku, deformitas, krepitasi, serta nyeri ketika melakukan gerakan supinasi dan pronasi. Pemeriksaan penunjang berupa X-Ray regio antebrachii posisi AP/ Lateral dapat membantu menegakkan diagnosis. Tujuan tatalaksana adalah mereduksi seakurat mungkin dengan mengembalikan panjang ulna ke ukuran semula, dimana caput radii biasanya akan tereduksi secara otomatis. Namun jika caput radii tidak tereduksi atau tidak stabil maka reduksi terbuka harus dilakukan. Komplikasi yang dapat terjadi berupa cedera nervus, malunion dan non union.
Diabetes gestacional e diabetes mellitus do tipo 2 pós gestação
Authors: Barros Larissa Moraes , Abreu Gabriel Candelária , Donadon Beatriz Oliveira Bastos
Published: November 2022

Este trabalho teve como objetivo analisar, através de uma revisão bibliográfica, a prevalência, diagnóstico, prevenção e tratamento da diabetes gestacional e diabetes mellitus tipo 2 pós diabetes gestacional. Para o embasamento teórico desta revisão foram usados 29 artigos acessados nas plataformas “PubMed” e “BVS”. De acordo com o levantamento bibliográfico, diabetes gestacional e hiperglicemia persistente pós-gestação são patologias muito comuns em mulheres que têm fatores de risco tais como idade avançada, obesidade e diagnóstico de diabetes gestacional no primeiro trimestre ou que foram tratadas com insulinização durante a gestação (em casos de diabetes mellitus tipo 2 pós-parto). Também se observou que a melhor maneira para diagnosticar o diabetes gestacional foi através do teste de glicemia capilar, ao passo que o diagnóstico do diabetes mellitus tipo 2 pós-gestação foi através do exame da curva glicêmica entre a 6a e a 12a semanas pós-parto. Porém, é recomendado realizar o exame de hemoglobina glicada um ano após o parto para complementar o rastreio. Concluímos que a melhor prevenção do diabetes mellitus tipo 2 pós-parto é a mudança no estilo de vida (praticar atividade física e melhorar a alimentação) e tratar o diabetes gestacional com metformina e/ou com a dieta diet em vez de insulina.
Otimização global do registro de nuvens de pontos 3D por interpolação linear esférica (Slerp) de quatérnios em circuitos fechados
Authors: Benevides Rubens Antonio Leite
Published: November 2022

Reconstruir digitalmente o mundo 3D a nossa volta é um tema que interessa a diversas áreas do conhecimento e tem vastas aplicações. Na última década, a quantidade de sensores LIDAR (Light Detection and Ranging) cresceu continuamente em função deste fato, o que desencadeou alta demanda pelo aprimoramento do produto bruto desta tecnologia, nuvens de pontos 3D. Neste contexto, o Laser Scaner Terrestre (LST) se estabeleceu como padrão de qualidade na digitalização 3D de ambientes complexos. Este instrumento utiliza o sensoriamento remoto ativo do tipo LIDAR para gerar nuvens de pontos, todavia devido ao modo de operação por varredura estas nuvens sofrem com obstruções na linha de visão do laser. A consequência disto é que, para obter a digitalização completa de um objeto diferentes locais são ocupados pelo sensor, onde cada posição nova estabelece um sistema de coordenadas relativo àquela posição. Estimar os parâmetros da transformação relativa entre estes sistemas é o problema conhecido como registro de nuvens de pontos 3D. Habitualmente, na reconstrução de um ambiente múltiplas nuvens de pontos são registradas ao longo de um circuito, e transformar todas as coordenadas destas nuvens para uma única origem global acumula os erros a cada transformação envolvida. Distribuir este erro ao longo dos parâmetros de orientação de todas as nuvens em relação a uma origem global é o problema abordado neste livro.
Nexus between energy intensity, human capital development, Trade and environmental quality in LIC, LMIC and UMIC: Evidence from GMM
Authors: Md Qamruzzaman
Published: November 2022

All countries, especially those still on the path to economic development, must work hard to protect the environment. The state with the most economic policy discussion and development because of its focus on fair economic growth, protecting the environment, saving energy, and ensuring there is enough energy for everyone. According to the Environmental Kuznets Curve (EKC) hypothesis, we should look for a U-shaped link between rising wealth per capita and emissions of nitrous oxide (N2O), agricultural methane (ACH4), and carbon monoxide (C.O.) (CO2). We also examine the links between G.D.P. growth, energy intensity, foreign direct investment (FDI), human capital, and CO2 emissions. Using a panel generalized linear model (G.M.M.), we found that trade increases emissions of N2O, ACH4, and CO2 by a large amount for all of S.S.A. and its income groups (Upper-Middle-Income Countries (UMIC), Lower-Middle-Income Countries (LMIC), and Low-Income Countries (L.I.C.)). We think that the EKC proves that future emission reductions are possible and that trade hurts the environment in all sample countries, no matter how developed their economies are. On the policy side, the research showed that domestic trade liberalization and foreign control of the economy are bad and that industrialization must be done in a way that is both energy efficient and secure.
Trilha peçonhenta
Authors: Guerra Leonan , Neto Luiz Caldeira Brant de Tolentino , Schetinger Maria Rosa Chitolina
Published: November 2022

Os acidentes causados por animais peçonhentos constituem grave problema de saúde pública, sobretudo em países tropicais. Sendo assim, aprofundar o conhecimento sobre eles e difundir informações por processos educacionais pode ser um caminho para prevenir acidentes e auxiliar na sensibilização dos estudantes, de que todos os animais, inclusive os peçonhentos, são de suma importância para o equilíbrio ecológico. O objetivo desse trabalho foi avaliar os efeitos da aplicação de um jogo como recurso didático em sala de aula, visando a discussão e a reflexão sobre a identificação dos animais peçonhentos e prevenção de acidentes. Essa pesquisa é parte de um estudo que foi desenvolvido com estudantes do 7° ano, de uma escola estadual, no município de Santa Maria (RS), no período de outubro de 2014 a julho 2015. A análise dos dados foi qualitativa, e para a coleta destes utilizou-se as respostas dadas pelos estudantes durante o jogo, além de roda de conversa. Os resultados obtidos evidenciaram que o ensino sobre animais peçonhentos foi favorecido pelo uso do jogo didático intitulado “Trilha peçonhenta”, pois os educandos tornam-se multiplicadores de informações corretas, não somente durante a atividade, mas com seus familiares e pessoas do seu convívio, podendo diminuir, assim, o número de acidentes envolvendo o ser humano e os animais peçonhentos.
Praying with Blathmac
Authors: Bergholm Alexandra
Published: November 2022

The mid-eighth-century Old Irish text known as the poems of Blathmac is a long devotional composition meditating on the mystery of Christ’s cross and its significance for salvation history. Since the discovery and subsequent publication of the text nearly six decades ago, the work has garnered considerable scholarly interest for its linguistic and socio-historical value, but many aspects of its devotional orientation remain less systematically explored. This article examines the poems’ devotional discourse by focusing on the intersections of martyrdom and memory in Blathmac’s composition. Taking as a starting point the text’s intended use as a prayer, the discussion considers how the text’s overarching interest in exemplary acts of self-sacrifice relates to the practices of ritual commemoration, and how these strategies of collective memory work to convey and sustain a shared understanding of Christian identity.
Independence Day in a would-be Christian nation
Authors: Kallinen Timo
Published: November 2022

When the West African nation of Ghana attained its independence from colonial rule in 1957, its traditional culture was to be promoted in all sectors of public life. Similarly, what was construed as Ghanaian traditional religion was to be treated equally with Christianity and Islam. The ritual offering of libations to ancestral spirits and deities was considered the Ghanaian equivalent to Christian and Muslim prayers, and it has been performed side by side with them in all sorts of national events. Later on, the libation ritual became a symbol of both Ghana’s religious diversity and its national culture, transcending religious divisions. Many Christian groups, especially from the Pentecostal-charismatic movement, have refused to accept the public status of the libation ritual in view of its alleged immoral ‘pagan’ associations. When the pouring of libations was removed from the Independence Day ceremonies held at the state capital in 2011, the public debate soon turned to the relationship between the government and Pentecostal churches, and accusations of religious intolerance were levelled. This article discusses how the arguments about the status of the ritual boil down to differences in semiotic ideology and notions about proper agency – namely, how forms of agency pertaining to words, objects, persons and spiritual beings involved in the ritual are understood differently by the disputants.
Stress-and-strain state of the rock mass in mining deposits in the Urals
Authors: Krinitsyn R.V.
Published: November 2022

With regard to mining at depths the issues of ensuring the chambers stability, the choice of their orientation and the support selection still at the design stage are particularly relevant. At depths, near large tectonic disturbances, the factor of natural rock pressure starts to play a defining role in the underground structures stability, and the constant growth of requirements for improving safety of underground structures predetermines the need to incorporate modern approaches to identify the stressstrain state using numerical simulation. Making design decisions without simulation can lead to a decrease in economic performance and production safety, and sometimes entail the impossibility of full recovery of reserves. The finite element simulation used in this work as one of the main methods for determining the optimal option for primary cutting of the ore body and mining a rich ore body located in close proximity to large-scale tectonic disturbance that provokes a complex stress state of the ore body itself. On a practical level, the finite element method can be discredited, and therefore a description of the sequence of techniques for constructing and calibrating finite element models of primary cutting of the ore body (mining options) is required for correct identification of the most suitable mining option, that is done in this work. The integrated approach includes: formation of complex spatial geometric model of ore bodies, taking into account the morphology of bedding; separation of the model into stages of development and forming different variants of development; determination of borderline conditions for Cauchy tensor correct task; determination of deformation model and assignment of physical and mechanical parameters; carrying out verification calculations; calculation of all model variants, their analysis and selection of the most optimal ore deposit mining technique; interpolation of data into geomechanical block model for the possibility of selecting and substantiating the supports parameters and calculating the stability of chambers using analytical tools.
VFR TOURISM MOTIVATION: A CASE STUDY OF YOUNG ACADEMICIANS
Authors: GÖKTEPE Sevinç
Published: November 2022

Visiting Friends and Relatives (VFR) tourism takes great attention from scholars in recent years. Due to its consisting a large part of the tourism market, understanding the motivations of VFR travelers is essential. Several reasons determine the motivations of VFR travelers. The duration of the trip, the attractions of the destination, the frequency of visits are some of these reasons.

In this study, the motivation of visiting friends or relatives was tried to be revealed by interviewing academicians with similar income and education levels. As a result of the interviews, it was revealed that traditions mostly affect VFR travels. In Turkish traditions, it is especially important to visit family elders and other relatives on holidays. Therefore, the duration of stay can take a few days. Another important factor is the budget. VFR travels are preferred to lodgings because they are more affordable. Participants stated that they preferred to stay with their friends rather than with their relatives.
ÇEVRİMİÇİ ZİYARETÇİ YORUMLARINDA ÇATALHÖYÜK NEOLİTİK KENTİ
Authors: HALAÇ Hicran Hanım , ULAŞ Ebru , KARAÇOR Furkan
Published: November 2022

Teknolojideki gelişim ivmesini en yakından takip eden sektörlerden biri turizm sektörüdür. Turizm sektörünün dijital ortama teması; işletmelere, ziyaretçilere, turistlere, ziyaret edilecek lokasyonlara uzaktan erişim olanağı sağlamıştır. Mevcut çalışmada dijital platformlara gelen ziyaretçi yorumları, Google Haritalar kapsamında ele alınmıştır. Çatalhöyük Neolitik Kenti’ni ziyaret eden yerli ve yabancı turistlerin ziyaret sonrası alan ile ilgili olumlu-olumsuz yorumları ve 5 yıldız üzerinden yaptıkları puan değerlendirmeleri içerik analizi yöntemi ile incelenmiştir. İlk ziyaretçi değerlendirmesinin yapıldığı 2012 yılı ve 01.11.2020 tarihi arasında antik kent için yapılmış 1321 ziyaretçi değerlendirmesi, SPSS paket programına aktarılmış ve ilişki arayıcı değerlendirmeler program üzerinden yapılmıştır.

Çatalhöyük Neolitik Kenti yeni yönetim planı hazırlığının devam ettiği süreçte, alana dair ziyaretçi görüş ve önerilerinin belgelenmesi ve aktarımı amacı ile hazırlanan mevcut çalışmada, olumlu ve olumsuz yorum içerikleri dokuz başlıkta kodlanmış, başlıklara gelen yorumlar sayısal veriler ile belgelenmiştir. Toplamda 420 ziyaretçi yorumu incelenmiştir. Olumlu ziyaretçi yorumlarında model ev ve ücretsiz giriş ifadeleri sıklığı en yüksek başlıklardır. Antik kent çevresinde bakımsızlık ve yol güzergâhında bilgilendirme eksikliği ise olumsuz yorumlarda en sık yer alan ifadeler olmuştur. Ziyaretçi yıldız değerlendirmelerinde, 1321 ziyaretçinin %74’ünün (981) alana dair memnuniyet düzeyi yüksek çıkmıştır. Alana 5 yıldız değerlendirmesi yapan ziyaretçilerin de yorumlarında eleştirilere yer verdiği, sonraki ziyaret planları için kazı yönetim ve görevlilerine önerilerde bulunduğu görülmüştür. Destinasyon imajında gerekli görülen ziyaretçi görüşlerine dijital platformlardan erişim imkanı mevcut çalışmada örneklenmiştir .
A CONCEPTUAL RESEARCH ON THE THERMAL TOURISM POTENTIAL OF ERZURUM
Authors: ÇETİNKAYA Mehmet Yavuz , YAĞCI Kamil , ÖNEK Muhammet
Published: November 2022

Coğrafi olarak dünyanın en önemli jeotermal kuşaklarından birinde yer alan Türkiye, sahip olduğu doğal termal su kaynakları ve nitelikleri açısından popüler termal turizm destinasyonlarından biri olarak kabul edilmektedir.Türkiye’nin termal turizm potansiyeli içerisinde, Doğu Anadolu Bölgesinde Palandöken Dağı eteklerinde kurulmuş olan Erzurum, tarihî, kültürel ve arkeolojik zenginliklerin yanında termal turizm bakımından da önemli bir potansiyele sahiptir. Bu araştırma, tarihsel süreç içerisinde coğrafi konumunun sağladığı avantajla sürekli yerleşim yeri olarak kullanılan Erzurum’un termal turizm potansiyelinin ortaya çıkarılmasını ve alternatif turizm türü olarak kullanılabilirliğini incelemenin yanında termal turizmin gelişmesini sağlayacak öneriler geliştirmeyi amaçlamaktadır. Bu amaçla termal turizm üzerine kavramsal olarak literatür taraması yapılmış ve daha önceki yıllarda yapılmış olan araştırmalar kapsamlı bir şekilde incelenmiştir. Araştırma, Erzurum’un başta Aziziye, Pasinler ve Köprüköy ilçeleri olmak üzere hemen hemen tüm çevresinde hem nitelik hem de nicelik olarak pek çok termal su kaynağına sahip olmasına rağmen bu potansiyelini etkili ve verimli bir şekilde kullanamadığını ortaya çıkarmıştır. Bu bağlamda Erzurum ilinin termal turizm potansiyelini değerlendirerek arzu edilen sonucu elde edebilmesi amacıyla mevcut durum göz önünde bulundurularak bazı öneriler geliştirilmiştir.