bluuebunny/crossref_metadata_2025 huggingface dataset:
ОСНОВНЫЕ НАПРАВЛЕНИЯ РАЗВИТИЯ ГИДРОБИОЛОГИИ
Authors: Зинченко Т.Д. , Розенберг Г.С.
Published: March 2023

В предлагаемом в качестве основы для научной дискуссии адаптированном варианте одной из глав монографии Т.Д. Зинченко и Г.С. Розенберга «Гидробиология 20-х годов XX века (ретрохроника)» рассмотрены некоторые направления развития современной гидробиологии, обсуждены проблемы общей (системной, продукционной, этологической гидробиологии, палеогидробиологии) и частной гидробиологии (санитарной, медицинской, токсикологической, радиологической, сельскохозяйственной, рыбохозяйственной, технической, космической), гидробиологического образования. Отмечена необходимость продолжения процесса ее «экологизации», совершенствования научных основ комплексной эксплуатации водных объектов.
Antioxidant and antimicrobial activities of White Radish
Authors: Sevindik Mustafa , Onat Cavit , Mohammed Falah Saleh , Uysal İmran , Koçer Oğuzhan
Published: March 2023

Since prehistoric times, humans have relied on plants for a wide variety of needs, including sustenance, shelter, thermal regulation, and medical treatment. Plants are significant organics because of the many ways they may be put to use. The white radish (Raphanus raphanistrum subsp. sativus (L.) Domin) was tested for its antioxidant and antibacterial properties, as were its tuber and aerial portions. A soxhlet was used to extract ethanol from plant material. The antioxidant and oxidant capacities were tested with the use of Rel Assay TAS and TOS kits. The agar dilution technique was used to test for antimicrobial activity against the bacteria and fungus included in the experiment. As a result of the studies, the TAS value of the tuber extract of the plant was measured as 6.698±0.187, the TOS value as 5.609±0.245 and the OSI value as 0.084±0.002. The TAS value of the herbal aerial parts extract was 4.689±0.223, the TOS value was 3.746±0.128, and the OSI value was 0.080±0.003. Inhibition of tuber extract was observed at concentrations varying between 25-100 against bacterial strains and 200 µg/mL against fungal strains. Aerial parts extract showed inhibition against bacterial strains at concentrations varying between 100-200 and against fungus strains at concentrations ranging from 200-400 µg/mL. As a result, it was determined that the white radish plant has significant antioxidant and antimicrobial activity.
Influencing Academic Achievement and Regional Mediating Effects of General High Schools on Local Apartment Prices Based on Spatial Hedonic Price Model
Authors:   Korean Association for Housing Policy Studies, Oh Jiyoung , Seo Wonseok
Published: March 2023

This study empirically analyzed the effect on housing prices according to the academic achievement of general high schools and the regional mediating effect using the spatial hedonic model. The main empirical analysis results are as follows. First, accessibility to general high schools had a positive effect on local apartment prices regardless of the type. It was found that the preferred high school type, which had the highest college entrance rate, had a greater influence. Second, a prestigious high school was more preferred when it comes to the type of high school closest to the apartment. This result seems to be due to the recognition that consumers in the local housing market place high value on the status of local prestigious high schools, and that there are many students with excellent grades in prestigious high schools. Consequently, there may be less incidence of juvenile delinquency, creating a positive effect on the residential environment around the school. Third, it was found that in an area where the regional effect on housing price is high, the closer an apartment is to a prestigious high school, the higher the apartment price can get. Through these results, this study confirmed that the characteristics of general high school academic achievement have a clear influence on apartment prices and that these influences appear differentially by region.
A singular manifestation of focal fibrous hyperplasia on the lateral border on both sides of the tongue – A case report and literature review
Authors: Oliveira Cavezzi Gabriel , Cavezzi Junior Orlando
Published: March 2023

Focal fibrous hyperplasia (FFH) is a pathology characterized by tissue enlargement as a result of increasing the number of inflammatory cells which receive chronic mechanical stimuli of low intensity that may affect gums, lip, palate, jugal mucosa and tongue. The aim of this article is to report a case of FFH on the lateral border on both sides of the tongue associated with the use of the Hyrax appliance in a hebiatric patient, whose chief complaint was chewing discomfort. This case was successfully treated by surgical excision as well as the removal of Hyrax appliances. Follow-up care provided the recovery of the patient's quality of life.
Influencia de la satisfacción e importancia de la educación física en el abandono deportivo
Authors: Aznar-Ballesta Antonio , Vernetta Mercedes
Published: March 2023

El objetivo del estudio fue analizar la influencia que la satisfacción, aburrimiento e importancia que le atribuyen los estudiantes a la asignatura de educación física, tiene sobre el abandono deportivo extraescolar, asociando los factores y determinando los motivos de abandono. Se utilizó un diseño transversal con una muestra de 925 alumnos de secundaria con edades entre 12 y 18 años, de los que 263 habían abandonado la práctica deportiva. Se aplicó un cuestionario ad hoc, la Escala de satisfacción adaptada a la educación física (ES-EF), la Escala de Importancia de la Educación Física (IEF) y la Escala de Motivos de abandono de la práctica de actividad físico deportiva. El alumnado que había abandonado la práctica mostró valores intermedios de satisfacción e importancia respecto a la asignatura. El principal motivo de abandono fue la falta de tiempo. Las chicas mostraron mayores porcentajes de abandono deportivo. La satisfacción predijo negativamente los motivos personales de abandono, la importancia y el aburrimiento fueron predictores positivos de los motivos ambientales/sociales y los motivos actitudinales respectivamente. Como conclusión, los docentes de EF deben implantar metodologías que favorezcan la satisfacción, teniendo en cuenta el posible agotamiento de los estudiantes.
Análisis del impacto de un programa formativo STEM en los modelos mentales y la actitud de docentes en formación
Authors: García-Yeguas Araceli , Arias Mª Dolores , González-García Francisco , Aguilera Morales David
Published: March 2023

La educación STEM cada vez produce más interés en el ámbito educativo. En la literatura podemos encontrar distintas definiciones, haciendo que su comprensión pueda resultar dispersa. En este trabajo analizamos la actitud de los docentes hacia este enfoque educativo y el modelo mental que conciben sobre STEM antes y después de vivenciar un programa formativo STEM. La muestra está compuesta por docentes del Grado de Educación Primaria en formación de la Universidad de Granada. Para conocer la actitud hacia STEM se ha usado el cuestionario TatSTEM con un pretest y un postest. Para analizar los modelos conceptuales se ha usado la clasificación “STEM como acrónimo”, “Resolución de problemas de la vida real como contexto”, “Ciencia como contexto”, “STEM como disciplinas separadas”, “Disciplinas integradas” e “Ingeniería como contexto”. Los resultados muestran  una mejora en la actitud hacia STEM tras la formación propuesta. Por otro lado, los modelos STEM han evolucionado desde modelos más simplista a modelos más complejos, produciendo un gran cambio respecto a STEM como disciplinas integradas.
Young EFL learners' pausing behavior: exploring pause thresholds in two proficiency levels

Authors: Garcés-Manzanera Aitor
Published: March 2023

The study of pausological behavior in L2 writing has been a matter of interest in recent years (see Lindgren & Sullivan, 2019), leading to a number of empirical studies which have explored pausing behavior from different angles. Among the many elements of pausological behavior, the pause threshold has aroused controversy in recent years (Alves et al., 2008) given its role in helping to discern lower-level and higher-level cognitive processes associated with L2 writing. While the research intent has focused recently on observing how pausological behavior varies according to the pause thresholds in adult L2 writers (Medimorec & Risko, 2017), this element of writing has not been examined in children L2 writers. For that purpose, this study analyzes pausological behavior and transcription fluency based on a picture-based story task by children L2 writers. Results indicate that pauses at word boundaries were more frequent than at sentence or paragraph boundaries. Likewise, the text boundary effect was not fully replicated, contrary to what studies in adult L2 writers have shown (see Wengelin, 2007).
FEATURES OF MUTATION DETECTION IN LONG-READ WHOLE GENOME SEQUENCING DATA
Authors: Кечин А.А. , Корюков М.А. , Боробова В.С. , Филипенко М.Л.
Published: March 2023

Технологии секвенирования третьего поколения позволяют идентифицировать не только точечные и короткие мутации, но и протяженные перестройки. В результате генерируется огромное количество данных, которое анализируется при помощи различных методов, в том числе машинного обучения. Целью работы стала отработка подходов к выявлению различных мутаций в данных полногеномного секвенирования технологией Oxford Nanopore. В результате были подобраны оптимальные параметры для BWA и minimap2 (картирование), Pisces (точечные мутации), Sniffles и Nanovar (крупные перестройки), а также сконструированы праймеры для валидации некоторых крупных перестроек.

Third-generation sequencing technologies make it possible to identify not only point and short mutations, but also large rearrangements. Therefore, a huge amount of data is generated, which is analyzed using various methods, including machine learning. The aim of the study was to develop approaches to identifying various mutations in Oxford Nanopore sequencing data. As a result, optimal parameters were selected for BWA and minimap2 (mapping), Pisces (point mutations), Sniffles and Nanovar (large rearrangements), and primers were designed to validate some large rearrangements.
DIGITAL MODELS OF QUARRY EXVAVATORS WORKLOADING FOR INFORMATION SUPPORT OF EQUIPMENT PARK EXPLOITATION
Authors: Доронин С.В. , Альшанская А.А.
Published: March 2023

Рассматривается возможность использования построенных цифровых моделей нагруженности карьерных экскаваторов в информационно-вычислительных системах управления парком технологического оборудования горных предприятий. Обсуждаются перспективы и целесообразность создания и применения цифровых двойников карьерных экскаваторов.

The possibility of using the developed digital models of quarry shovels workloading in information and computing systems for managing the park of technological equipment of mining enterprises is considered. The prospects and feasibility of creating and using digital twins of quarry excavators are discussed.
ON THE RELATIONS IN SCIENCE BY THE EXAMPLE OF THE ANALYSIS OF DISSERTATIONS
Authors: Леонова Ю.В.
Published: March 2023

С использованием базы данных авторефератов диссертаций была проанализирована динамика развития связей между персонами, выступающими в качестве соискателей и научных руководителей (консультантов) диссертаций с целью изучения структуры научных связей ученого (научное окружение ученого), структуры и динамики развития научных коллективов и научных школ.

Using the database of dissertation abstracts, the dynamics of the development of relations between persons acting as applicants and scientific supervisors (consultants) of dissertations was analyzed in order to study the structure of scientific relations of a scientist (scientific environment of a scientist), the structure and dynamics of the development of research teams and scientific schools.
Black Carrot (Daucus carota ssp. sativus var. Atrorubens Alef.) Extract Protects against Ethanol-induced Liver Injury via the Suppression of Phosphodiesterase 4 mRNA Expression
Authors:   Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, Japan, A Kitano , T Norikura ,   Department of Nutrition, Aomori University of Health and Welfare, Japan, I Matsui-Yuasa ,   Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, Japan, H Shimakawa ,   Konan Chemical Industry, Co., Ltd., Japan, M Kamezawa ,   Konan Chemical Industry, Co., Ltd., Japan, A Kojima-Yuasa ,   Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, Japan
Published: March 2023

We examined the protective effects of Black Carrot Extract (BCE) on Alcoholic Liver Disease (ALD) using in vivo and in vitro models. In an in vivo ethanol-Carbon Tetrachloride (CCl4)-treated rat model, BCE treatment suppressed serum alanine aminotransferase and aspartate aminotransferase activity. BCE also suppressed ethanol- and CCl4-induced alcoholic liver disease. Furthermore, we observed that the BCE or butanol-extracted fraction of BCE (BCE-BuOH) recovered the cell viability of in vitro ethanol-treated hepatocytes. BCE-BuOH also suppressed the production of reactive oxygen species induced by ethanol to the control level. Moreover, BCE-BuOH regulated the activities of three alcoholic metabolism-related enzymes: cytochrome P450 2E1 activity was suppressed at the posttranslational level, alcohol dehydrogenase activity was increased at the posttranslational level, and aldehyde dehydrogenase 2 activity was increased at the transcriptional level. Novel findings in this study include an increase in intracellular Cyclic Adenosine 3’,5’-Monophosphate (cAMP) levels in hepatocytes with the simultaneous addition of ethanol and BCE-BuOH and the suppression of changes in the activities of three enzymes upon treatment with an inhibitor of cAMP-dependent protein kinase. Our study also found that BCE-BuOH suppressed the expression of phosphodiesterase 4b mRNA, which increased intracellular cAMP levels. These results suggest that BCE is useful for the treatment of ALD.
Ways to improve the social efficiency of small and medium-sized businesses in the context of digitalization
Authors: Denikin A. V. , Denikina Z. D. , Kubikova N. V.
Published: March 2023

This article discusses the issue related to ways to improve the social efficiency of small and medium-sized businesses in the context of digitalization. The authors consider key aspects concerning the internal component of business processes through the prism of a behaviorist approach – study the role of human capital in the formation of social efficiency of the company, identify ways of measuring it and the role of job satisfaction, as well as the impact of this indicator on the productivity of the workforce as a whole. The social efficiency of a company is a complex phenomenon, therefore, the study of ways to improve it through internal business processes is important. As the main conclusions to the work, the authors formulate recommendations for improving the level of job satisfaction through the integration of the latest digital technologies. An important place in this article is devoted to the study of the issue related to the factors of increasing job satisfaction. The authors consider the main groups of factors that form the level of employee satisfaction with work. Based on the identified factors, the authors make recommendations to improve the social efficiency of the company. In the final part of the article, the authors make conclusions regarding the further development of the social efficiency of small and medium-sized businesses in the conditions of digitalization.
Benchmarking in silico Tools for Cysteine pKa Prediction
Authors: Awoonor-Williams Ernest , Golosov Andrei , Hornak Viktor
Published: March 2023

Accurate estimation of the pKas of cysteine residues in proteins could inform targeted approaches in hit discovery. The pKa of a targetable cysteine residue in a disease-related protein is an important physiochemical parameter in covalent drug dis- covery, as it influences the fraction of nucleophilic thiolate amenable to chemical protein modification. Traditional structure-based in silico tools are limited in their predictive accuracy of cysteine pKas relative to other titratable residues. Additionally, there are limited comprehensive benchmark assessments for cysteine pKa predictive tools. This raises the need for extensive assessment and evaluation of methods for cysteine pKa prediction. Here, we report the performance of several computational pKa methods, including single structure and ensemble-based approaches, on a diverse test set of experimental cysteine pKas retrieved from the PKAD data- base. The dataset consisted of 16 wildtype and 10 mutant proteins with experimentally measured cysteine pKa values. Our results highlight that these methods are varied in their overall predictive accuracies. Among the test set of wildtype proteins evaluated, the best method yielded a mean absolute error of 2.3 pK units highlighting the need for improvement of existing pKa methods for accurate cysteine pKa estimation. Given the limited accuracy of these methods, further development is needed before these approaches can be routinely employed to drive design decisions in early drug discovery efforts.
DFT and TDDFT Studies of Silicon Analogs of Fluorescein Derivatives
Authors: Weerasinghe Krishanthi , Wang Lichang
Published: March 2023

Fluorescein derivatives play an important role in the field of biological and fluorescent sensors. To tune the spectroscopic properties many attempts have been made including extending conjugation, substituting the central carbon by nitrogen or introducing electron withdrawing groups and replace the oxygen bridge atom by other elements such as N, C, S, Se, and Te. In this paper we report density functional theory (DFT) and time-dependent DFT (TDDFT) studies of silicon analog of fluorescein derivatives with oxygen replaced by Si, C, and Ge. Among the different silicon analogs, the most conjugated molecule 4 showed red shift in absorption wavelength (495 nm). The OH position of molecule 2 has a significant effect on the spectral properties of the silicon analogs of the fluorescein. Since aggregation is very common in most of the fluorescein and it is interesting to study the effect of aggregation, we also studied dimerization of molecule 1 in silicon analog of fluorescein derivative and the results show that two absorption bands are formed with red shift compared to monomer.
Materials Science Optimization Benchmark Dataset for High-dimensional, Multi-objective, Multi-fidelity Optimization of CrabNet Hyperparameters
Authors: Baird Sterling G. , Parikh Jeet N. , Sparks Taylor D.
Published: March 2023

Benchmarks are crucial for driving progress in scientific disciplines. To be effective, benchmarks should closely mimic real-world tasks while being computationally efficient, allowing for accessibility and repeatability. Developing surrogate models that can be indistinguishable from the ground truth observation within the explored dataset bounds dramatically reduces the computational burden of running benchmarks without sacrificing quality, but this requires a large amount of initial data. In the fields of materials science and chemistry, relevant optimization tasks can be challenging due to their complexity, which includes hierarchical, noisy, multi-fidelity, multi-objective, high-dimensional, and non-linearly correlated variables. Additionally, they may include mixed numerical and categorical variables that are subject to linear and non-linear constraints. Simulating or experimentally verifying such tasks can be difficult, which is why benchmarks are essential. This study aimed to overcome these challenges by generating 173219 quasi-random hyperparameter combinations across 23 hyperparameters and using them to train CrabNet on the Matbench experimental band gap dataset (Computational runtime: 387 RTX-2080-Ti GPU days). The results were stored in a free-tier shared MongoDB Atlas dataset, creating a regression dataset that maps hyperparameter combinations to metrics such as MAE, RMSE, computational runtime, and model size for the CrabNet model trained on the Matbench experimental band gap benchmark task. To simulate the actual simulations, heteroskedastic noise was incorporated into the regression dataset, and bad hyperparameter combinations were excluded. Percentile ranks were computed within each group of identical parameter sets to capture heteroskedastic noise, rather than assuming Gaussian noise as is done in traditional approaches. This approach can be applied to other benchmark datasets, bridging the gap between optimization benchmarks with low computational overhead and realistically complex, real-world optimization scenarios.
Molecular Insights into the Binding Interaction of the First Class of Potent Small Molecules Disrupting the YAP-TEAD Protein-Protein Interaction
Authors: Awoonor-Williams Ernest , Dickson Callum , Furet Pascal , Golosov Andrei , Hornak Viktor
Published: March 2023

Disruption of the YAP-TEAD protein-protein interaction is an attractive therapeutic strategy for oncology to suppress tumour progression and cancer metastasis. YAP binds to TEAD at a large flat binding interface (~3500 2) devoid of a well-defined druggable pocket, so it has been difficult to design low molecular weight compounds to abrogate this protein-protein interaction directly. Recently, work by Furet and coworkers (ChemMedChem 2022, DOI: 10.1002/cmdc.202200303) reported the discovery of the first class of small molecules able to efficiently disrupt the transcriptional activity of TEAD by binding to a specific interaction site of the YAP-TEAD binding interface. Using high-throughput in silico docking and structure-based drug design, they identified a virtual screening hit from a hot-spot derived from their previously rationally designed peptidic inhibitor. Given advances in rapid high-throughput screening and rational approaches to peptidic ligand discovery for challenging targets, we analyzed the pharmacophore features involved in transferring from their peptidic to small molecule inhibitor that could enable small molecule discovery for such targets. Here, we show that pharmacophore analysis augmented by solvation analysis of molecular dynamics trajectories can guide the designs while binding free energy calculations provide greater insight into the binding conformation and energetics accompanying the association event. The computed binding free energy estimates agree with experimental findings and offer useful insight into structural determinants that influence ligand binding to the TEAD interaction surface, even for such a shallow binding site. In general, our results provide rationale for the structure-based design efforts in compound optimization that led to a significant gain in potency among the first class of potent small molecule YAP:TEAD protein-protein inhibitors.
Click-electrochemistry for the rapid labeling of virus, bacteria and cell surfaces
Authors: Depienne Sébastien , Bouzelha Mohammed , Courtois Emmanuelle , Pavageau Karine , Lalys Pierre-Alban , Marchand Maia , Alvarez-Dorta Dimitri , Nedellec Steven , Marin-Fernandez Laura , Grandjean Cyrille , Boujtita Mohammed , Deniaud David , Mével Mathieu , gouin sebastien
Published: March 2023

The remodeling of microorganism surfaces with biomolecules is a powerful tool to study the role of membrane receptors in chemical biology and to develop drug delivery systems in gene therapy using viral vectors and cell-based therapies. Methods for direct covalent ligation of these surfaces remain poorly reported, and mostly based on metabolic engineering for bacteria and cells functionalization. In the latter case, a tagged precursor must first be enzymatically metabolized and delivered to the outer cell membrane to become available for chemo-selective labeling. While effective, a faster method avoiding the bio-incorporation step would be highly complementary. This would also need to be compatible with organisms showing poor levels of precursor assimilation or lacking the metabolic function. Here, we used N-methylluminol (NML), a fully tyrosine-selective protein anchoring group after one-electron oxidation, to label the surface of viruses, living bacteria and cells. The functionalization was performed electrochemically and in situ by applying a 750 mV vs Ag/AgCl electric potential to aqueous buffered solutions of tagged NML containing the viruses, bacteria or cells. The electro-coupling was performed with NML anchors bearing a bioorthogonal azide, biotin, or carbohydrate (mannose and N-acetyl galactosamine) handles. The broad applicability of the click-electrochemistry method was explored on recombinant adeno-associated viruses (rAAV2), E. coli (Gram-) and S. epidermis (Gram+) bacterial strains, and HEK293 and HeLa eukaryotic cell lines. Surface electro-conjugation was achieved in minutes to yield functionalized rAAV2 that conserved both structural integrity and infectivity properties, and living bacteria and cell lines that were still alive and able to divide. As NML activation immediately stops if there is no current, the method offers reproducible temporal control on the degree of surface functionalization. Thus, click-electrochemistry should significantly expand the scope of bioconjugation methods.
Generation and Transfer of Triplet Electron Spin Polarization at Solid-Liquid Interface
Authors: Yabuki Reiya , Nishimura Koki , Hamachi Tomoyuki , Matsumoto Naoto , Yanai Nobuhiro
Published: March 2023

The photoexcited triplet state of dyes can generate highly polarized electron spins for sensing and dynamic nuclear polarization. However, while triplets exhibit long spin-lattice relaxation times (T1) on the microsecond scale in solids, the polarization quickly relaxes on the nanosecond scale in solution due to the rotational motion of chromophores. Here, we report that the immobilization of dye molecules on a solid surface allows molecular contact with a liquid while maintaining high polarization and long T1 as in a solid. By adsorbing anionic porphyrins on cationic mesoporous silica gel, porphyrin triplets exhibit high polarization and long T1 at the solid-liquid interface of silica and toluene. Furthermore, porphyrin triplets on the solid surface can exchange spin polarization with TEMPO radicals in solution. This simple and versatile method using the solid-liquid interface will open the way for utilizing the photo-induced triplet spin polarization in solution, which has been mainly limited to the solid-state.
Describing nuclear quantum effects in vibrational properties using molecular dynamics with Wigner sampling
Authors: Tikhonov Denis , Vishnevskiy Yury
Published: March 2023

In this work, we develop a molecular dynamics method, combining the simple Maxwell-Boltzmann statistics with the generally applicable standard Wigner sampling. The resulting implemented single-parameter procedure, termed simplified Wigner sampling, has been extensively benchmarked by calculating vibrationally averaged rotational constants and vibrational spectra of several molecules and by comparing with results from other methods. The procedure has been also combined with the Andersen thermostat for simulation of NVT-ensembles.
MODELLING THE IMPACTS OF SELECTED WATERSHED MANAGEMENT STRATEGIES ON SEDIMENT REDUCTION UPSTREAM OF SHIRORO DAM, NIGERIA
Authors: ADEOGUN ADENIYI GANIYU , GANIYU HABEEB OLADIMEJI , OKUNADE ABRAHAM BABAJIDE , AMOO OSENI TAIWO
Published: March 2023

This research utilized a regulated hydrological model, Soil and Water Assessment Tool (SWAT) interfaced with Geographical Information System (GIS), in studying the effectiveness of the chosen watershed management strategies on sediment reduction upstream of Shiroro dam, Nigeria. Selected management approaches were modelled while calibration and validation of the model were achieved using observed streamflow data. Findings indicated a good correlation during calibration and validation period. Application of reforestation, vegetative filter strips and stone bunds in the watershed reduces sediment production by 27 %, 39 %, and 15 % respectively. Thus, the sediment management scenarios depicted within this research are considerably sustainable and effective.
EXPERIMENTAL OPTIMIZATION OF AERODYNAMIC DRAG COEFFICIENT OF A MINIBUS MODEL WITH NON-SMOOTH SURFACE PLATE APPLICATION
Authors: BAYINDIRLI CIHAN , CELIK MEHMET
Published: March 2023

In this study non-smooth surface plate application was experimentally investigated to flow control around a scaled minibus model in a wind tunnel. 1/15 scaled minibus model and non-smooth surface plate were designed in SolidWorks® Cad program and produced in 3-D printer. It was focused on decrease of drag coefficient of vehicle with non-smooth surface plate by reducing flow separation. The experimental tests carried out 4 free stream velocities between the speed of 13.90-27.40 m/s and 2.62x105-5.18x105 Reynolds numbers. In wind tunnel tests Reynolds number independence was used to ensure dynamic similarity. The blockage rate was 10.68 %. It was determined that the using of non-smooth surface plate e on the front roof area of minibus model decreased to drag coefficient by an average of 1.03%. This reduction rate can decrease fuel consumption of vehicle about 0.5% at high speeds.
SELECTION OF SOCIAL MEDIA PLATFORMS USING FUZZY PROMETHEE METHOD WITH DIFFERENT SCENARIO TYPES
Authors: BOZDEMİR MELİKE KÜBRA EKİZ , ALKAN ATAKAN
Published: March 2023

Social media are widely and mostly utilized in many areas to increase advertising, client relations, tourism, journey and many others by means of members or organizations. Social Media Platforms (SMPs) are becoming increasingly popular in the world. The selection of SMPs, which might be widely and mostly utilized by members or organizations, becomes a critical and complex problem. Moreover, some problems that need to be investigated which consist of the reason for the use of different SMPs, purpose, and frequency of use. In this study, we have investigated to explain these problems via questionnaire which evaluates by undergraduate pupils (N = 173). Therefore, we have created twelve different scenarios that are different weights and thresholds and handled the selection and ranking of SMPs by fuzzy Preference Ranking Organization Method for Enrichment Evaluation (PROMETHEE) I and II. Consequently, we able to conclude that "Which SMPs were more preferred?", "What are the reasons for selection of SMPs? and "Which criteria are more important for this selection?". In addition, this study can be guiding an infrastructure for the content of new SPMs in the future.
LOW-CEMENT DOSAGE REFRACTORY CONCRETE WITH LOW THERMAL CONDUCTIVITY
Authors: PAUNESCU LUCIAN , VOLCEANOV ENIKO , PAUNESCU BOGDAN-VALENTIN , SURUGIU IOANA MONICA
Published: March 2023

Super-aluminous refractory concrete (over 94 % Al2O3) with low dosage of cement (9 %) was made, its physical, thermal, and mechanical characteristics being considered suitable for the intermediate layer of a steel casting ladle: porosity of 29.31 %, the apparent density of 2.32 g·cm-3 thermal conductivity of 1.45 W·m-1·K-1, and compressive strength of 34.8 MPa (after heat treatment at 1500 ºC). The aim of the research was achieving a super-aluminous concrete with low-cement dosage, which would have acceptable thermal insulation properties, so that the heat loss through this refractory lining layer would be significantly reduced compared to the reference situation.
FLUID DYNAMIC STUDY USING RTD IN A PACKED REACTOR AND EVALUATING FLOW PATTERN MODELS ON THE CHEMICAL CONVERSION. AN APPROACH TO REAL BEHAVIOR
Authors: SERNY KLAUS , PACHECO MILEXI
Published: March 2023

In this work was done a fluid dynamic study in an experimental packed reactor using RTD exposing bimodal and modal behavior when it was varied the particle diameter and bed presenting flow channels, dead zones in the vessel and lateness of the material mixture in the equipment. Additionally, using flow pattern models was estimated the chemical conversion with greater approximation to the experimental value. This result could be use in the scaling stages of the process and minimize overdesigns.
Consultoría Política. Una práctica antropológica en el mercado laboral
Authors: Torres Álvarez Sebastián
Published: March 2023

El objetivo de este artículo ha sido exponer una forma en la que la práctica antropológica puede adentrarse en la consultoría política, a través de un estudio de caso realizado para una campaña de diputación local en la Ciudad de México durante la terna electoral del 2021. Para el estudio señalado, se llevaron a cabo 207 encuestas a lo largo de 29 colonias que componen dicho distrito electoral. El instrumento fue diseñado para obtener información sobre las principales problemáticas percibidas por los habitantes del distrito sobre su entorno, así como su intención de voto, incluyendo preguntas sobre la posibilidad de cambiar dicha intención. El instrumento permitió referenciarlo por colonias, lo cual ayudó a entender la diversidad de las problemáticas locales. No obstante, más allá de los resultados obtenidos, este es un ejercicio de ejemplificación de las oportunidades de una disciplina en la prestación de servicios a sujetos o instituciones políticas.
Hubungan Penerapan Perilaku Hidup Bersih Dan Sehat (PHBS) Orang Tua Dengan Kejadian Stunting Di Kelurahan Air Hitam Kota Samarinda
Authors: Dhefiana Tika , Reni Suhelmi  , Hansen
Published: March 2023

Stunting merupakan masalah gizi nasional dengan pravelensi kejadian cukup tinggi setiap tahun yang tercatat 23,4% pada tahun 2021. Secara regional, terdapat 403 balita tercatat stunting di Kota Samarinda sedangkan 87 balita stunting dilaporkan pada Puskesmas Juanda tahun 2021. Salah satu penyebab tidak langsung stunting adalah faktor lingkungan melalui perilaku hidup bersih dan sehat yang secara signifikan memengaruhi pola asupan gizi anak. Tujuan penelitian ini adalah untuk mengetahui hubungan antara tingkat pengetahuan, sikap, dan perilaku ibu balita dalam implementasi PHBS dengan kejadian stunting pada balita berusia 24 hingga 59 bulan di Kelurahan Air Hitam Kota Samarinda. Populasi yang ditetapkan pada penelitian ini ialah ibu yang mempunyai balita berusia 24 hingga 59 bulan di Posyandu Srikaya dan Posyandu Al-Azhar. Sampel yang ditentukan dalam penelitian ini sebanyak 50 responden dengan metode penelitian analitik dengan pendekatan cross sectional. Pengumpulan data dilakukan pada bulan Mei 2022 melalui wawancara langsung responden menggunakan kuesioner dan pengukuran antropometri pada balita. Hasil penelitian menunjukkan bahwa sebesar 22% balita mengalami stunting, terdapat hubungan antara tingkat pengetahuan dan penerapan PHBS ibu dengan kejadian stunting (p-value = 0,030 dan 0,017). Diharapkan masyarakat dapat lebih peduli dan dapat menerapkan PHBS di lingkungan mereka sebagai langkah awal pencegahan stunting.
Mangrove litter production in Sei Carang waters of Tanjungpinang City, Riau Island Province
Authors: Dharma Putra Urai Dian , Lestari Febrianti , Susiana Susiana
Published: March 2023

Sei Carang waters are a mangrove ecosystem area with a fairly wide area coverage, Sei Carang waters have mangrove ecosystems. This study aims to determine the level of mangrove density and production of mangrove litter in Sei Carang. This research was conducted May-June 2022 located in Sei Carang. Observation locations were determined by survey methods and point selection using purposive sampling. Then observations using line transects using a plot measuring 10x10 m. There were 6 species found at the study site, namely: Rhizophora apiculata, Rhizophora mucronata, Bruguiera gymnorhiza, Bruguiera sexangula, Sonneratia alba, Xylocarpus granatum. The most common types were found at station 1 where there were 6 of them, and at station 3 there were only 4 types. With density levels ranging from 1633.33 ind/ha to 2300 ind/ha. And also the highest litter production value occurs at station 3 with an average value of 7.21 (gbk/m2) and the lowest occurs at station 2 with an average value of 2.27 (gbk/m2), and the parameters of the Sei Carang waters are still relatively low. good for the life of the mangrove ecosystem when compared to seawater Quality Standards Government Regulation of the Republic of Indonesia No. 22 of 2021 concerning the Implementation of Environmental Protection and Management, Attachment VII.
Comparison of probiotics with different concentrations on the growth and survival rate of Bonylip Barb (Osteochilus vittatus)
Authors: Saadah Fatimatus , Lisminingsih Ratna Djuniwati , Latuconsina Husain
Published: March 2023

Bonylip barb (Osteochilus vittatus) is one of Indonesia's local fish which is starting to bloom in cultivation. One of the important needs in the development of fish farming is feed, to increase feed efficiency by providing probiotics which play a role in increasing growth, survival rates, digestibility, feed efficiency, the immune system and the composition of beneficial bacteria in the digestive tract of fish. This study aims to compare the concentration of different probiotics in commercial feed on the growth and survival of barley nilem (Osteochilus vittatus). The research was conducted at Pandaan Aquaculture Installation (IPB), Pasuruan Regency, East Java. Experimental study using a completely randomized design (CRD) with four treatments and three replications. Statistical analysis to compare growth performance (length and weight) and survival of nilem fish used analysis of variance (ANOVA) test. The results showed that there were differences in the growth of weight, length, and survival of barley nilem (Osteochilus vittatus) on commercial feed with different concentrations of probiotics. Where there is a tendency that the higher the concentration of probiotics in commercial feed, the higher the growth in length and weight and survival of nilem fish (O. vittatus).
Community structure of macrozoobenthos in seagrass bed on Barrang Lompo Island
Authors: Ayu Ayu , Nursyahran Nursyahran , Hidayani Mesalina Tri
Published: March 2023

Macrozoobenthos are bottom animals that play an important role in the productivity of waters in seagrass beds. This study aims to determine the species composition, density of macrozoobenthos, community structure of macrozoobenthos and the relationship between seagrass density and density of macrozoobenthos. The research method used is purposive sampling method, this method is taken based on certain reasons and criteria. This research was conducted in June-July 2022 on Barrang Lompo Island. Sangkarrang District, Makassar City. There were 26 species found consisting of 4 classes namely Bivalvia, Gastropods, Chepalopods and Crustacea with a total of 283 ind and dominated by the Gastropod class, both from the number of species and individual density. Macrozoobenthos community structure on Barrang Lompo Island at station I and II with a moderate diversity index (H'), moderate uniformity index (E') and low dominance index (D). The types of seagrass found at stations I and II were Enhalus acoroides, Thalassia hemprichii, and Cymodocea rotundata. The regression results of the relationship between seagrass density and macrozoobenthos density on Barrang Lompo Island show a weak relationship, which means that seagrass density has no relationship with macrozoobenthos density but macrozoobenthos density is influenced by physical and chemical factors of the waters and the type of sandy substrate.
Educación jurídica y tecnología: El potencial para democratizar el conocimiento y el poder jurídicos
Authors: Pearce Russell , Lochan Hema
Published: March 2023

The current technological transformation of legal education, including computer-based, interactive, and online modes of instruction, represents “one of the most dramatic technological revolutions in history, if not the most dramatic.”1 As the AI-based technological revolution accelerated dramati- cally in the 1990s, many commentators responded to the “commercial spread of the Internet” with utopian faith in its potential to equalize and democratize knowledge and power. This faith gave way to a second wave of comments criticizing the “damages… to historically subservient groups”, the threat of “disinformation” and polarization of democracy, the consolidation of power in Big Tech and authoritarian governments, and the threat to privacy in general.2 Today’s commentators are challenged to determine if and how to address these harms while realizing the potential benefits of AI-powered technology, especially given the impact and use of technology during the forced experimentation that took place during the COVID-19 pandemic.In assessing the potential impact of technology on legal education, this paper focuses primarily on legal education in the United States, although we will include some comparative ideas. Part I provides the context for our analysis – how legal education functions today to maintain hier- archy and inequality regardless of any specific reliance on technology. Part II examines the way law schools currently use online legal education, and its minimal impact on democratizing legal education. Part III will explore the potential of technology to improve legal education, including democratizing legal knowledge and power.
Völkerrechtsblog como infraestructura para la Comunicación Científica Global y Educación Abierta en la Era Digital
Authors: Kunz Raffaela , Riegner Michael , Schmalz Dana
Published: March 2023

Open Access publishing has numerous advantages and is said to be beneficial to the human rights to information, education, and science. Yet, the transition to Open Access has been slow, with the legal discipline lagging far behind. Moreover, Open Access brought about new risks of exclusion and hegemony. The aim of this article is to discuss the role of blogs, long considered as pioneers in the debate, in contributing to a sustainable Open Access transformation in the legal discipline. As editors and founders of Völkerrechtsblog, we have followed these developments closely and have also been part of them. After briefly introducing Völkerrechtsblog, the article addresses the question of how blogs and digital Open Access publishing can contribute to education in the legal discipline. The article concludes with some reflections on future visions for blogs and sustainable Open Access publishing in the legal areas.
A CRISE DO CONSTITUCIONALISMO GLOBAL: PROPOSTAS E REFLEXÕES
Authors: Frota Hidemberg Alves da
Published: March 2023

Este artigo científico debruçou-se sobre a crise do constitucionalismo global na contemporaneidade, por meio de estudo baseado em revisão bibliográfica, norteado pela literatura mais atual acerca desse eixo temático, colhida de periódicos científicos de língua inglesa especializados na matéria. Delinearam-se noções basilares sobre o constitucionalismo global e se realizou a sua contextualização no contemporâneo, à luz dos atravessamentos políticos, sociais e econômicos que, na atualidade, influem sobre e desafiam a viabilidade desse projeto constitucional. Após, quadripartiu-se a discussão, estabelecendo-se o diálogo do constitucionalismo global seja com o neoliberalismo, seja com o Direito Internacional dos Direitos Humanos, seja com o multiculturalismo e, ao fim, propôs-se novo locus para o poder constituinte, com a finalidade de divisar novos caminhos que permitam ao constitucionalismo global manter a sua relevância no debate constitucional e ampliar os seus horizontes hermenêuticos.
ARTIGO 316, PARÁGRAFO ÚNICO DO CPP: Considerações em face ao iminente ativismo judicial e a flexibilização da previsão legal
Authors: Lima Alexsandro da Silva , Paschoalick Marília Bachi Comerlato
Published: March 2023

O presente trabalho tem como objeto a análise do parágrafo único do artigo 316 do Código de Processo Penal que trata sobre a obrigação do juízo revisar a cada 90 dias, a necessidade ou não, da manutenção da prisão cautelar imposta ao réu, sob pena de tornar a prisão ilegal, caso não seja considerado o artigo mandamental. Ocorre que em análise na jurisprudência e doutrina, mediante o dispositivo supracitado percebeu-se divergências quanto ao que impõe o dispositivo legal. Embora sem respostas definitivas, apresenta uma reflexão razoável sobre o tema à medida que buscou considerar como fundamento e norte do estudo o princípio constitucional do devido processo legal. No Brasil há nítida tentativa de promover uma justiça mais democrática, no sentido de ser menos intolerante com os mais vulneráveis; todavia, há um sistema perpetuado na gênese penal que parece dificultar que uma nova legislação consiga encontrar aplicabilidade nos tribunais brasileiros. Nesse sentido, o referido artigo e seu parágrafo revela ter sido promulgado com a intenção de evitar injustiças com os presos preventivos sem justa causa. Porém, lamentavelmente, se vê o novel dispositivo processual penal ser modificado a partir da interpretação dada pelas cortes superiores.
A PRIORIZAÇÃO DA VACINAÇÃO CONTRA COVID-19 DAS MULHERES EM SITUAÇÃO DE CÁRCERE: O DIREITO FUNDAMENTAL À SAÚDE
Authors: Cordovil Emanuelle de Souza Oberst
Published: March 2023

O presente trabalho traz à baila reflexões pautadas na vulnerabilidade das Mulheres Privadas de Liberdade do sistema prisional do Estado do Rio de Janeiro no que concerne a crise sanitária mundial ocasionada pelo vírus COVID-19 (SARS-CoV-2) e as políticas públicas adotadas pelo Estado capazes de conter a propagação do vírus e garantir os direitos fundamentais a esse grupo de vulneráveis. Sob este prisma, diante da implacável crise sanitária, compete ao Estado a responsabilidade de promover políticas públicas de forma efetiva que possam permitir o acesso a saúde, mitigar a insalubridade das mulheres em situação de privação de liberdade no sistema prisional. O crescente contingente de infectados, bem como a célere disseminação do vírus imerge a identificação de situações de vulnerabilidade na qual as mulheres em situação de privação de liberdade são inseridas. O direito a saúde é garantido a todos, logo, as mulheres em situação de cárcere são mais suscetíveis a contaminação, haja vista, que em nosso sistema prisional há violações às garantias previstas constitucionalmente. Por essa razão, é de suma importância que o Estado promova como política de enfrentamento a pandemia a priorização do grupo de Pessoas Privadas de Liberdade para recebimento da vacina através do Plano Nacional de Operacionalização da Vacinação contra Covid-19.
A SELETIVIDADE PENAL NO SISTEMA PENITENCIÁRIO BRASILEIRO NA ATUALIDADE
Authors: Jorge Filho Geraldo Tadeu , Silva Juliana Absher de Sá e , Brígido Edimar
Published: March 2023

O artigo visa abordar as questões da seletividade penal no cenário do sistema penitenciário brasileiro na atualidade. O estudo se deu por meio de uma pesquisa bibliográfica direcionada aos conceitos basilares da criminologia em conjunto com a análise de dados da criminalização do país nos últimos anos. A partir da Teoria da Reação Social, também conhecida como “Labelling Approach”, a qual é responsável por uma mudança paradigmática no estudo criminológico, pretende-se demonstrar que o crime não depende a cominação legal apenas, mas também da reação social frente ao ato. Diante do aporte teórico, busca-se analisar dados a respeito do sistema carcerário nacional, observando assim os principais órgãos de informação, como o World Prison Brief e Infopen, os quais revelam a situação carcerária brasileira. Com isso, o presente trabalho objetiva verificar a incidência preponderante do fenômeno da seletividade penal em relação a determinados setores sociais.