bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPACTO DA CONCORRÊNCIA DE MERCADO NA QUALIDADE DO SERVIÇO EDUCACIONAL
Authors: Penteado junior Luiz Carlos
Published: February 2025

Este artigo objetiva demonstrar a frágil relação entre as avaliações interna e externa da qualidade do serviço escolar e a imbricada relação entre pressão exercida pelo mercado e a qualidade do serviço educacional, tomados como base os processos de aferição dos serviços educacionais oferecidos por quatro unidades da Rede Educacional Adventista situadas na região do Recôncavo Baiano. Nesta análise denominamos de avaliação interna da qualidade aquela realizada pela própria instituição ou por sua mantenedora, utilizando indicadores padronizados e validados pela própria organização, eleitos como adequados à checagem e mensuração da qualidade em face dos objetivos corporativos; ao passo que, consideramos como avaliação externa, aquela que expressa a percepção do cliente ou tomador do serviço, com dados levantados a partir de pesquisa de opinião através de instrumento já validado na literatura e amplamente utilizado neste tipo de verificação. Partindo do pressuposto de que a escola é um espaço rico e complexo de aprendizagem e convivência, onde a atuação do diretor pode ser decisiva para o sucesso ou fracasso dos objetivos escolares, checou-se ainda, de forma secundária, o impacto que a avaliação do desempenho do gestor escolar exerce sobre a percepção do cliente a propósito da qualidade final do serviço prestado pela escola.
A IMPORTÂNCIA DO ENSINO RELIGIOSO PARA O DISCIPULADO DO ADOLECENTE NO CONTEXTO DA EDUCAÇÃO ADVENTISTA
Authors: Liessi Hebert Davi , Souza Rodrigo Tergilene de
Published: February 2025

Este trabalho tem o intuito de estudar a importância do Ensino Religioso para o discipulado do adolescente no contexto da educação adventista. Por meio da revisão bibliográfica, foi utilizada uma abordagem de pesquisa qualitativa do material para que os objetivos propostos fossem atingidos. Observou-se que a educação adventista tem como propósito restaurar a imagem de Deus em seus filhos, sendo isso possível por meio do discipulado. Para tal cumprimento, existe grande necessidade de educadores alinhados com os princípios e valores da instituição, que estejam dispostos a embarcar no desafio de ensinar aos adolescentes o que é religião, tanto de maneira teórica quanto, sobretudo, de maneira prática. O educador terá maior êxito em discipular ao sê-lo um discípulo, bem como ao compreender o perfil e as necessidades dos seus alunos – buscando atender suas características físicas, mentais, sociais e espirituais – e ao utilizar métodos e estratégias que possibilitem alcançar a mente e o coração daqueles adolescentes que o ouvem.
Malignant Transformation of Linear Porokeratosis
Authors: Niclavos Nidhin , Aithal Vijay
Published: February 2025

Porokeratosis (PK) is a rare disorder characterised by clonal expansion of keratinocytes without neoplastic transformation. However, malignant transformation, particularly to squamous cell carcinoma (SCC), is a documented complication. This case report describes a 58-year-old female with a 10-year history of progressively worsening, linear plaques on her left lower extremity. Skin biopsies initially suggested PK, leading to treatment with acitretin and cyclosporine. Subsequent biopsies revealed a moderately differentiating keratinising type of SCC arising within a background of linear PK. The patient ultimately underwent surgical excision and radiation therapy. This case highlights the potential for malignant transformation in PK, particularly the linear subtype. We review the literature on PK subtypes, risk factors for malignancy and management strategies. This case report emphasises the importance of clinical vigilance for malignant transformation in PK, particularly the linear variant. Early diagnosis and appropriate management are crucial for optimal patient outcomes.
Innocence in Disguise: Vulvar Hidradenoma Papilliferum
Authors: Shah Ankita Siddharth , Sadhwani Monal , Bhide Dhanashree Santosh , Kulkarni Vinay , Vaidya Pradyumna Prakash , Patki Anil H.
Published: February 2025

The vulvar region contains a high concentration of apocrine, eccrine, anogenital mammary-like glands and pilosebaceous units. Vulvar hidradenomas are benign tumours originating from anogenital mammary-like glands and typically manifest as small, painless nodules on the vulva. They can clinically resemble pyogenic granulomas or granuloma inguinale. The preferred treatment method is local surgical excision. This case report discusses two cases of women diagnosed with vulvar hidradenomas, highlighting their characteristic clinical presentation and management approach. These cases serve as a reminder for clinicians to consider this rare tumour in differential diagnoses of nodular lesion on vulva with beefy red erosive surface, alongside conditions such as sexually transmitted infections and other benign or malignant tumours.
Unveiling the therapeutic potential of Olax psittacorum: An approach to explore its safety and efficacy in experimental rats
Authors: Mansingh Pragyan Parimita , Adhikari Lopamudra , Dhara Moonmun
Published: February 2025

Objectives:

A traditional herb, Olax psittacorum (Lam.) Vahl. used in Odisha, India, for the management of different ailments, including aphthae ulcers. O. psittacorum leaf ethanolic extract was used in the present study to quantitatively evaluate the phytoconstituents present in ethanolic extract for its antibacterial, anti-oral-ulcer and free radical-scavenging properties.

Materials and Methods:

The leaves were extracted with ethanol, and the quantitative estimations were assessed by total tannin, flavonoid as well as phenolic contents. The antioxidant efficacy was evaluated using different free radical scavenging assays, and antimicrobial activity was assessed for Gram-positive as well as Gram-negative bacteria. Acute toxicity and sub-chronic toxicity studies were assessed. The anti-oral-ulcer property of the extract was observed using an acetic acid-induced ulceration in vivo model.

Results:

The extract yield was 45.6%, and the total phenolic, flavonoid and tannin content was determined to be 97.6 mg gallic acid equivalent/g, flavonoid content was 754.8 mg quercetin equivalent/g of extract, and the total tannin content was 21.81 mg tannic acid equivalent/g of extract. The extract exhibited free radical scavenging efficacy with a median inhibitory concentration of <50 µg/mL. Acute toxicity studies revealed no death associated with the extract. Subchronic toxicity studies showed no significant changes in biochemical, haematological or histological parameters. However, the extract exhibited good antioxidant, antimicrobial and anti-oral-ulcer activity by inhibiting ulceration by 70% and 83%, with doses of 100 and 200 mg/kg, respectively, on day 5.

Conclusion:

The present work confirms potent antioxidant and antimicrobial, along with anti-oral-ulcer properties and is considered safe for therapeutic purposes, suggesting that it could be an appropriate herbal source in treating associated ailments.
Assessment of neurodevelopmental outcomes in preterm infants using risk stratification score
Authors: Nemadi Nikita Deepak , Patil Sharanagouda , Patil Arundhati , Mangshetty Roopa
Published: February 2025

Objectives:

Preterm birth, defined as delivery occurring before 37 weeks gestation, poses a significant public health challenge, as an increasing number of infants who survive face neurodevelopmental disabilities. Preterm infants face various health challenges, including anaemia, hyperbilirubinaemia, feeding and respiratory difficulties, retinopathy and intracranial haemorrhage, which often lead to long-term cognitive, learning and behavioural impairments due to structural brain abnormalities. (1) To study risk stratification tools based on intrauterine and neonate insult. (2) To study and predict major neuro-developmental disability like cerebral palsy, mental retardation, blindness, deafness at 1 year of age.

Material and Methods:

The study included 30 preterm infants, categorised by risk levels, after obtaining ethical clearance and parental consent. Developmental follow-up assessments were adjusted for prematurity and conducted using tools such as the Amiel-Tison angle (ATA), scarf sign, Denver developmental screening test (DDST) and Vineland social maturity scale (VSMS). Visual and hearing assessments were checked for retinopathy and deafness. Primary outcomes at 1 year included death or major neurodevelopmental delays, such as cerebral palsy, mental impairment, blindness and profound hearing loss.

Results:

In this study of 30 preterm infants, 83% weighed over 1.5 kg with a mean birth weight of 1.73 kg, and amongst those under 1.5 kg, 80% had abnormal developmental outcomes. The mean gestational age was 32 ± 1 weeks. Major neurodevelopmental delays (NDD), including cerebral palsy and global developmental delay, was observed in 16.6% of the infants, while 30% experienced minor NDD. Preterms with major NDD had higher intervention needs, with 40% requiring positive pressure ventilation and intubation, and 20% requiring chest compressions, 26.6% having abnormal ATAs. Statistically significant perinatal risk factors for poor neurodevelopmental outcomes included extreme prematurity (≤32 weeks), birth weight (<1.7 kg), need for resuscitation and prolonged ventilation (>7 days).

Conclusion:

The study identified extreme prematurity, low birth weight, need for resuscitation and prolonged ventilation as key predictors of poor neurodevelopmental outcomes in preterm infants. Infants were stratified into low and high-risk groups to plan follow-up intensity and early intervention. Tools such as ATA, DDST, and VSMS aid in the early detection of neurodevelopmental disabilities, emphasising the importance of standardised follow-up programmes in neonatal units to improve outcomes for high-risk infants.
Автоматизированная сегментация пользователей с применением RFM-анализа в маркетинговых стратегиях
Authors: Святов Р.С.
Published: February 2025

Актуальность исследования обусловлена необходимостью повышения эффективности маркетинговых стратегий за счет автоматизированной и кастомизируемой сегментации клиентов. В рамках данной работы предложена универсальная система управления клиентскими данными, в основе которой лежит RFM сегментация с возможностью настройки гибкой логики, а также возможностью интеграции с различными внешними системами. Традиционные CRM-системы и ручные методы RFM сегментации ограничены в функционале и не всегда удовлетворяют потребности бизнеса в гибкости и интеграции с различными источниками данных. В работе были выявлены недостатки традиционных CRM-систем и предложены точки улучшения описываемой системы. Дополнительно был проведен эксперимент, в котором сравнивались полученные RFM сегменты на основе предложенной архитектуры с автостратегиями Яндекса в рекламной платформе Яндекс.Директ. Применение системы показало значительные преимущества в сравнении с автостратегиями, включая увеличение числа покупок на 30,71 % на примере магазина одежды. Полученные результаты подтверждают практическую ценность системы для оптимизации маркетинговых кампаний и повышения конверсии. Результаты имеют практическую значимость для компаний, нуждающихся в кастомизированных решениях и интеграциях. Для дальнейшего развития предлагается совершенствование метода RFM-сегментации путем внедрения алгоритмов машинного обучения, а также поиск дополнительных эффективных каналов для использования создаваемых сегментов.

The relevance of the study is determined by the need to enhance the effectiveness of marketing strategies through automated and customizable customer segmentation. This work proposes a universal customer data management system based on RFM segmentation with the ability to configure flexible logic, as well as the capability to integrate with various external systems. Traditional CRM systems and manual RFM segmentation methods are limited in functionality and do not always meet the business needs for flexibility and integration with various data sources. The study identifies the shortcomings of traditional CRM systems and suggests points for improvement in the described system. Additionally, an experiment was conducted comparing the RFM segments generated using the proposed architecture with Yandex's auto-strategies in the Yandex.Direct advertising platform. The application of the system showed significant advantages over auto-strategies, including a 30.71% increase in purchases in the case of a clothing store. The results confirm the practical value of the system for optimizing marketing campaigns and improving conversion. The results are of practical importance for companies in need of customized solutions and integrations. Further development is proposed, focusing on improving the RFM segmentation method by implementing machine learning algorithms and exploring additional effective channels for utilizing the generated segments.
Effect of tera Indonesia exercise on BMI and resting pulse rate in people aged 50 years and above
Authors: Widodo Dirga , Kinanti Rias Gesang , Andiana Olivia
Published: February 2025

Changes experienced by the elderly are a decrease in physical fitness such as heart-lung and circulatory fitness. This results in the elderly getting tired easily when doing physical activity. So it takes a physical activity that produces results for the elderly with the right dose and dose. This article aims to examine the Indonesian Tera Gymnastics on BMI and pulse frequency. The method used is an experimental research model, using a one group pre-test and post-test design framework through a process before and after treatment in the form of Tera Gymnastics carried out 3 times 1 week in 4 weeks. The instrument used in collecting BMI data is measuring body weight and height. The technique of collecting assessment samples using Purposive Sampling. The sample obtained was 33 people with the research subject was COOM (Branch of Community Sports Organization) Gymnastics Tera Indonesia who participated in training at Slamet Park, Malang City. Data  processed descriptively using statistical tests. The results of the analysis showed that Tera Gymnastics did not have a significant effect on reducing BMI (p = 0.281 > 0.05). However, there was a significant effect on the decrease in resting pulse rate before and after exercise (p = 0.000 < 0.05). In addition, the average pulse rate after exercise was in the light intensity category, according to the fitness level of the elderly. In conclusion, Tera Gymnastics is effective in reducing resting pulse rate, which contributes to improved cardiovascular health, although it does not significantly affect BMI.
Application of cooperative learning model in increasing students' motivation in doing physical fitness activities
Authors: Dinali Lipran , Gunawan Gunawan , Mursalim Mursalim
Published: February 2025

Cooperative learning models are known to be effective in increasing student engagement and motivation, especially in physical fitness activities. This study aimed to investigate the application of cooperative learning models to increase students' motivation to participate in physical fitness activities at SMANOR Tadulako. This study used a mixed methods approach, combining quantitative and qualitative data from surveys and observations. A total of 100 students were involved in the study, who were divided into groups for the cooperative learning intervention during physical education sessions. The results showed a significant increase in motivation levels, where students demonstrated higher participation, teamwork, and enthusiasm in physical fitness activities. The findings highlight the role of cooperative models in creating a supportive and engaging learning environment that encourages active participation and better learning outcomes.
Supramolecular polymerization through rotation of light-driven molecular motors
Authors: Schiel Philippe , Maaloum Mounir , Moulin Emilie , Nyrkova Irina , Semenov Alexander , Dattler Damien , Accou Lou-Ann , Christoulaki Anastasia , Buhler Eric , Plamont Rémi , Lehn Jean-Marie , Giuseppone Nicolas
Published: February 2025

Molecular motors are capable of acting on their environment through their unique capacity to generate nonreciprocal autonomous motions at the nanoscale. Although their operating principles are now well understood, artificial molecular motors have yet to demonstrate their general capacity to confer novel properties on (supra)molecular systems and materials. Here, we show that amphiphilic light-driven molecular motors can adsorb onto an air‒water interface and form Langmuir monolayers upon compression. Under UV-irradiation, the surface pressure isotherms of these films reveal a drastic shift toward smaller molecular areas as a consequence of motor activation. We explain this counterintuitive phenomenon by the rotation-induced supramolecular polymerization of amphiphilic motors through a non-thermal annealing process, which is limited by the maximal torque they can deliver (≈10 pN.nm) and leads to the formation of highly organized patterns. This serendipitous discovery highlights the opportunities offered by molecular motors to control supramolecular polymerization by motion-induced processes and to form active nanostructures for the design of innovative materials.
Nickel-Catalyzed Gas-Free Reductive Carbonylation of Aryl Thianthrenium Salts to Access Aryl Amides and Aryl Thioesters
Authors: Chen Chen , Ding Lu-Yao , Zhang Xiao-Xu , Chen Guan-shen , Zhu Yan-Ping , Ni Chunjie , Zhu Bolin
Published: February 2025

A nickel-catalyzed site-selective reductive carbonylation of arenes via aryl thianthrenium salts is described. Using Mo(CO)6 as a convenient solid CO source and reductant, and employing nitroarenes and sulfonyl chlorides as readily available nitrogen and sulfur sources, a range of aryl amides and aryl thioesters were successfully synthesized in moderate to good yields. The utility of this transformation is demonstrated through the synthesis of antimicrobial agents and the latestage functionalization of biorelevant molecules.
Asymmetric Ring Contraction of 2-Hydroxypyranones by Borrowing Hydrogen Biocatalysis
Authors: Liu Yuchang , Rolfes J. D. , Deska Jan
Published: February 2025

Ring contraction reactions facilitate easy access to carbo- and heterocyclic scaffolds from readily available precursors and have therefore enjoyed great popularity as a strategy in organic synthesis for a long time. By repurposing commercial alcohol dehydrogenases as borrowing hydrogen biocatalysts, we were able to develop a rare example of an enzymatic ring contraction methodology, where racemic 2-hydroxypyranones can be converted in an enantioconvergent manner to the corresponding 5-membered butenolides. The redox self-sufficient transformation delivers gamma-lactones in excellent optical purities and was successfully employed in the total synthesis of an Osmunda metabolite. Moreover, the biocatalytic tool was incorporated into a multi-step cascade consisting of six enzymes, achieving the formal enantioselective dearomatization of a furfuryl alcohol to deliver the corresponding saturated gamma-lactone in >99% ee.
Cobalt-Catalyzed Enantioselective and Diasterodivergent Con-struction of Distal Chiral C-N Diaxes
Authors: Das Abir , Kumaran Subramani , Maity Pritam , Premkumar J. Richard , sundararaju basker
Published: February 2025

Herein, we report an efficient method for the synthesis of atropisomers with distal 1,3–C–N diaxes using the co-balt/Salox system via C–H and N–H annulation with benzamide and sterically hindered alkynes. This one-step, step-economical process operates at room temperature with oxygen from air as the sole oxidant, removing the need for metal oxidants, photocatalysts, or electricity. The reaction is compatible with a broad range of arylamides and alkynes, providing high yields and excellent enantioselectivity (up to >99% ee). Experimental and DFT studies indicate that the migratory insertion is the rate-determining step, while C–H activation is the enantio-determining step.
Ion-Pair Hydrogen Atom Transfer Catalysis Enables Cr-Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes
Authors: Arii Suguru , Yu Zonghan , Chen Hongyu , Mitsunuma Harunobu , Kanai Motomu
Published: February 2025

We report a catalytic allylation of ketones using simple hydrocarbon alkenes, enabled by a synergistic system comprising chromocene and photo-activatable ion-pair hydrogen atom transfer (IP-HAT) catalysts derived from a thiophosphoryl imide and N-heteroaromatics. This catalyst system generates highly nucleophilic, electron-rich allylchromium(III) species directly from unactivated alkenes, demonstrating broad applicability to various ketones, including aromatic, aliphatic, and multifunctional ketones. The reaction proceeds under mild conditions with high functional group tolerance. The modular design of the IP-HAT catalysts allows precise tuning of redox potential and HAT activity, with the enhanced reduction potential of the reduced N-heteroaromatics catalyst playing a pivotal role in efficiently regenerating the electron-rich chromocene(II) catalyst.
Power Series Representation of Reaction Rates in Chemical Kinetics and Its Physical Interpretation
Authors: Qiu Jia
Published: February 2025

This paper introduces a power series framework for modeling chemical reaction rates, offering a mathematically flexible and physically interpretable alternative to traditional power-law models. By expressing reaction rates as multivariate power series of reactant concentrations, this approach captures the contributions of multi-molecular interactions and synergistic effects, which are often neglected in conventional models.
Cu-Controlled Enantiodivergent Pd-Catalyzed Stille Cross-Coupling Reactions
Authors: Ralph Glenn , Reghuvaran Santha Asha , Agyemang Nana , Ma Xinghua , Zuschlag Daniel , Murray Benjamin , Biscoe Mark
Published: February 2025

We report an enantiodivergent Pd-catalyzed cross-coupling reaction between unactivated enantioenriched alkylcarbastannatrane nucleophiles and aryl electrophiles in which the stereochemical course of the reaction is dictated by the inclusion or omission of a Cu(I) co-transmetalating agent. Use of a new electron-deficient biarylphosphine ligand (MaPhos) is required to promote the previously unreported stereoinvertive transmetalation pathway for unactivated secondary alkylstannanes. When a Cu(I) salt is included as a co-transmetalating agent, the stereochemical course of the reaction changes from stereoinvertive to stereoretentive. Thus, both enantiomers of the cross-coupling product can be accessed in high enantiopurity using a single achiral ligand. Mechanistic investigations suggest that net-stereoretentive alkyl transfer, in the presence of Cu(I), results from consecutive stereoretentive transmetalations from tin to copper and copper to palladium. In contrast, direct alkyl transmetalation from tin to palladium proceeds primarily via a stereoinvertive pathway that is facilitated by the presence of electron-deficient ligands.
Entropy-based Regularized Regression for Advanced Distribution of Relaxation Times Deconvolution
Authors: Py Baptiste , Wang Zilong , Wang Yuhao , Ciucci Francesco
Published: February 2025

Electrochemical impedance spectroscopy (EIS) coupled with distribution of relaxation times (DRT) analysis is a robust framework for characterizing electrochemical systems. However, DRT deconvolution is often plagued by spurious peaks, hindering accurate process identification and quantitative parameter estimation. To overcome this critical limitation, we rigorously evaluate entropy-based regularization within the standard regularized regression framework for DRT deconvolution. Building upon initial investigations, this study provides a detailed and quantitative evaluation of entropy-regularized DRT using a comprehensive suite of simulated impedance spectra, encompassing various impedance models and noise levels, and experimental data from lithium-ion batteries, fuel cells, and solar cells. Our results demonstrate that entropy regularization consistently outperforms conventional ridge regression, achieving significantly improved accuracy in DRT recovery and effectively eliminating spurious peaks. Furthermore, we demonstrate the novel capabilities of the entropy method for Bayesian DRT uncertainty quantification through sampling and for the simultaneous analysis of multiple impedance spectra. These findings establish entropy-based deconvolution as a superior and versatile technique for robust and insightful electrochemical system characterization, advancing the reliability of DRT analysis in electrochemistry.
NMR reaction monitoring robust to spectral distortions
Authors: Domżał Barbara , Grochowska-Tatarczak Magdalena , Malinowski Przemysław , Miasojedow Błażej , Kazimierczuk Krzysztof , Gambin Anna
Published: February 2025

Nuclear magnetic resonance spectroscopy (NMR) is one of the most potent analytical chemistry methods, providing a unique insight into molecular structures. Its non-invasiveness makes it a perfect tool for monitoring chemical reactions and determining their products and kinetics. Typically, the reactions are monitored by a series of 1H NMR spectra acquired at regular time intervals. Even such a straightforward approach, however, often suffers from several problems. In particular, the reaction may cause the sample inhomogeneity, resulting in a non-homogenous magnetic field and distorted spectral lineshapes. When the studied process is fast, the hardware correction (shimming and locking) cannot be applied on the fly, and the spectral quality degrades over the course of the reaction. Moreover, when non-deuterated solvents have to be used in the reaction mixture, a magnetic field-stabilizing system (deuterium lock) cannot work. Consequently, the spectra have distorted lineshapes, reduced resolution, and randomly varying peak positions, making them challenging to analyze quantitatively with standard software. In this paper, we propose a conceptually new approach to quantitative analysis of a series of distorted spectra. The method is based on a Wasserstein distance and can effectively quantify the components of a reaction mixture without a need for peak-picking. We provide open-source software requiring minimum input from the user, i.e., a set of spectra indexed by time.
Revisiting Boron Cluster Dihydrogen Bonding: Improved Reference Energies and Benchmark of Localized Coupled Cluster and DFT Methods
Authors: Santra Golokesh
Published: February 2025

Dihydrogen bonds involving boron clusters have gained significant attention in chemistry, biology, and medicine. The reference interaction energies of diH-norm and diH-linear datasets (J. Fanfrlík et al., ChemPhysChem 2020, 21, 2599), which include such bonds both in bent and linear configurations, have been re-evaluated at the gold level. This re-evaluation utilizes explicitly correlated MP2-F12 near the complete basis set limit, CCSD(F12*)/cc-pVQZ-F12, and a (T) correction from conventional CCSD(T)/haV{T,Q}Z calculations. Relative to the updated reference data, Fanfrlík's original reference shows very small root mean square deviations, resulting from significant error compensation between the [CCSD-MP2] and (T) high-level corrections. Furthermore, the revised reference is employed to assess the performance of various localized-orbital coupled-cluster approaches, such as PNO-LCCSD(T), DLPNO-CCSD(T1), and LNO-CCSD(T), at their respective “Normal”, “Tight”, “vTight”, and “vvTight” accuracy settings. For these methods, gradually increasing the basis set size and tightening the accuracy cutoffs improves their performance. For the dihydrogen bonds in diH-norm set, two cost-effective methods with no noticeable loss in accuracy are PNO-LCCSD(T)/Tight/haV{T,Q}Z and DLPNO-CCSD(T1)/TightPNO/CPS(6,7)/haV{T,Q}Z. On the other hand, for the diH-linear set, LNO-CCSD(T)/vTight/haV{T,Q}Z and DLPNO-CCSD(T1)/TightPNO/CPS(6,7)/haV{T,Q}Z are the recommended low-cost methods. Among the more economical density functional methods, r2SCAN-3c demonstrates remarkably good accuracy at a very cheap cost. Additionally, for hybrid and double-hybrid functionals, the incorporation of range separation significantly enhances performance.
Predicting Pore Limiting Diameter in Metal-Organic Frameworks Using Only Metal-Linker Building Blocks
Authors: Koohi-Moghadam Mohamad , Mohammadi Ahmad , Li Hongyan , Sun Hongzhe
Published: February 2025

Metal-organic frameworks (MOFs) show important potential in applications such as gas storage, catalysis, and drug delivery. However, the vast chemical space of MOFs makes experimental exploration impractical. While existing computational models often require the full MOF structure to predict key properties, we introduce a deep learning approach that predicts the pore limiting diameter (PLD) using only the metal-linker building blocks. Our method employs a 3D convolutional neural network (CNN) trained on spatial features derived from the 3D coordination of atoms within metal-linker complexes. We constructed a dataset of 25,529 MOFs from CoREMOF-2019 and Tobacco databases, deconstructed them into metal-linker units, and applied voxelization to generate 3D features. These features were then used to train a 3D CNN model, achieving an R² value of 0.86 on an unseen test set. By enabling accurate PLD prediction without requiring the full MOF structure, our approach facilitates early-stage screening and rational design of MOFs. The data and source code for our model are available at https://github.com/ClinicalAI/MOF_LPD_Prediction.
VERTICAL FARMING IN URBAN AGRICULTURE: OPPORTUNITIES, CHALLENGES, AND FUTURE DIRECTIONS
Authors: Gurung Lalendra , Rawal Janak Singh , . Puspa RC , Joshi Ganesh Raj , Mandal Ashmita
Published: February 2025

Vertical farming has turned out to be one of the modern and innovative methods of developing urban agriculture to meet necessities such as food security, sustainability, and effective use of resources as the world is increasingly turning into urban centers, besides facing a future of climatic change. This review article aims to review the state of the art, opportunities, issues, and prospects of vertical farming. By using the technological means of hydroponics, aeroponics, and aquaponics, vertical farming benefits from activities such as resource-saving, the lower use of water, and the ability to produce products year-round. The paper further analyzes the economic profitability, environmental advantage, and social relevancy of the vertical farming system, which includes decreasing transportation-related costs, minimizing the impacts on ecological life and producing quality crops without using many pesticides. However, such excellence comes with drawbacks that include, high capital investment, usage of energy, technicalities and regulations in vertical farming. Additionally, the range of crops that are currently produced in vertical farms remains rather limited, and there are issues related to the environmental consequences of nutrient runoff and waste management. It is therefore necessary to effort towards establishing ways and means to innovate, in consultation with other farmers as well as other stakeholders, and develop policies that will help to enhance the implementation of vertical farming to increase the production of such crops to meet the demands of the growing population in the future.
OPTIMIZATION OF ROCK PHOSPHATE USE AND EFFECT ON SOYBEAN GRAIN YIELD AND YIELD COMPONENTS ON AN ANDOSOL AND ACRISOL OF CAMEROON
Authors: Nanganoa Lawrence T. , . Foncha Felix , . Kamdem N. Franck Gilles , . Djocne F. Christiane , . Christopher Suh , . Francis A. Ngome
Published: February 2025

Modulation of rock phosphate fertilizer dose in soybean cultivation is crucial for maximizing plant growth and grain yield while ensuring efficient use of resources and environmental sustainability. This study evaluated rock phosphate (RP) dose to produce soybean on Leptic Andosol in Foumbot and Acrisol in Mbalmayo, respectively in the West and Centre regions of Cameroon. This split-plot experiment consisted of five fertilizer rates (control-no input and four Phosphorus (P) rates of 0, 30, 60 and 90 kg P /ha respectively) and two soybean varieties (TGX 1910-14 F and TGX 2001-24 DM) laid out in randomized complete block design with each treatment replicated three times. Plots containing the different P rates also had N (25 kg / ha) and K (40 kg / ha) straight fertilizers. Analysis of variance showed that fertilizer application significantly increased (P < 0.01) the number of pods and seeds, aboveground dry weight, and grain yield of the soybean varieties at both locations. There was an outright grain yield and economic benefit because of fertilizer application which increased with addition of phosphorus in the fertilizer mixtures. The grain yield response to phosphorus fertilizer was fitted to quadratic and square root models. The two models predicted maximum yields which were close to the experimental maximums recorded at P rates of 30 kg / ha (TGX 2001-24 DM: 5.04 and 4.89 t / ha) and 60 kg / ha (TGX 1910-14 F: 4.72 and 4.38 t / ha) at Foumbot and Mbalmayo respectively. The average optimum P fertilizer recommendations for soybean estimated by square root model (29.41 kg P/ ha) was considerably lower than that given by the quadratic equation (45.61 kg P/ ha) for both sites but only slightly lower the experimental dose of 30 kg P/ ha. Taking into account the yield and cost benefit analysis of the soybean seeds, fertilization with 30 kg P/ ha can be recommended.
CHARACTERIZATION AND FERTILITY CAPABILITY CLASSIFICATION OF SOILS ALONG RIVER KADUNA WATERSHED, NORTH-WESTERN NIGERIA
Authors: . Obasi S.N , . Obasi C.C. , . Alhassan G.A , . Alawode Y.O , . Nnabuihe E.C
Published: February 2025

This research work was carried out along river Kaduna watershed and aimed at characterizing some soil properties as well as carrying out a fertility capability classification for some arable crops grown in the location. A total of six profile pits were dug and characterized. Parameters employed in FCC study were Type, Subtrata type and Condition modifiers. The studied soils were dominated by soil texture class of silt clay loam. Almost all studied soils (pits 1, 2, 3, 5 and 6) had their textures ranged from Silt clay loam at the top horizons to silty loam or silt clay down the horizons. The only exception to this was the pit 4 which was dominated with silty loam at the top and its lower horizon. Soil pH was moderately acidic (pH > 5.0< 6.0), with the exception observed only in Pit 4 where pH was more acidic; 4.92 as measured in CaCl2. Classification under condition modifiers revealed that all studied locations except Pit 1 had a limitation of dryness (d) in all investigated locations suggesting a situation in which soils experience dryness > 60 consecutive days/year within 20 cm to 60 cm depth. Effective Cation Exchange Capacity (ECEC) (e) was not a limitation in the studied soils except in Pit 4 as all other ECEC values were higher than 6 Cmol.kg – 1 soil below which suggests serious leaching of exchangeable cations. The studied soils had a major challenge of low nutrient reserve, (exchangeable K < 0.20 c mole kg -1 soil). Application of organic substances rich in exchangeable basic cations especially K should be adopted by farmers around river Kaduna watershed. Also, the use of river Kaduna for irrigation purposes should be maximized to enhance dry season farming since rainfall duration is short in North Western Nigeria.
IN VITRO EVALUATION OF BOTANICALS AGAINST FUSARIUM SPP. CAUSING DAMPING OFF IN OKRA
Authors: . Pooja KC , . Hemant Raj Awasthi
Published: February 2025

Damping off is one of the important fungal diseases of okra. It is a widely prevalent and destructive disease affecting the initial plant stand of a crop that causes 20-30% losses. Fusarium spp. are the most important causal agents of damping off since they are frequently associated with the disease. The cheap, eco-friendly, safe, and sustainable management of the disease through botanicals is focused on the present study, as plant extracts prevent pollution, are non-phytotoxic, and are easily biodegradable in contrast to chemical fungicides. An experiment was conducted to evaluate the efficacy of two plant extracts of garlic (Allium sativum) and onion (Allium cepa) at three different concentrations (5%, 10%, and 15%) using the poisoned food technique against Fusarium spp. in vitro in a Completely Randomized Design. All the tested plant extracts significantly inhibited the mycelial growth of the pathogen in comparison to the control. The data on the mycelial growth of the pathogen were recorded on the 3rd, 5th, 7th, and 9th days of incubation. After the 9th day, among the tested plant extracts, the maximum growth inhibition of the pathogen was shown by (15%) garlic (74.13%), followed by (10%) garlic (52.99%), which was statistically at par with (5%) garlic (51.87%), and by (15%) onion (25.42%). Minimum growth inhibitions were shown by (5%) onion and (10%) onion, which are (8.84%) and (11.89%), respectively. The results showed plant extracts can be used as a potential alternative for the management of disease.
STUDY OF PHENOLOGICAL GROWTH STAGES OF SIX DIFFERENT CULTIVARS OF APPLE (Malus spp) IN MUSTANG, NEPAL
Authors: Saud Subash , Bhattarai Nitisha , Atreya Padma Nath , Dhakal Suman , Bohara Amrit Kumar
Published: February 2025

For proper orchard management, the phenological study of fruit trees is crucial. To study the phenological growth stages of different apple cultivars, a study was carried out at Temperate Horticulture Development Centre, Marpha, Mustang. The study was conducted from January to August 2023. The study was conducted for 6 cultivars of an apple available at Temperate Horticulture Development Center (Saune, Tsukura, Red Delicious, Golden Delicious, Royal Delicious and Rich a Red Delicious) where trees of each cultivar are replicated 4 times in Randomized Complete Block Design. The phenological stages of different cultivars were studied from the reference date which consists of 9 different stages (dormant, silver tip, green tip, half-inch green, tight cluster, pink, bloom, petal fall and fruit set. Climatic variables (temperature, relative humidity and rainfall) were estimated from the automatic weather station present in the development center. Data analysis was done through R Studio. The study of flowering phenology revealed that Tsukura (94.00 DARD) was the earliest and Golden Delicious (114.25 DARD) was the most late to reach a fruit set stage. The average blooming period of the typical flower of different apple cultivars was 10 days. The fruit set took place approximately a week after the completion of the full bloom period.
DIGITAL DIPLOMACY AS A MEANS OF STRATEGIC STATE COMMUNICATION
Authors: Kononenko Valery , Komarova Tetiana
Published: February 2025

The problem of digital diplomacy as a means of strategic communication of the state is considered. The authors consider different approaches to defining this phenomenon. Digitization of social processes affects diplomacy and its practical implementation. The changes concern institutions and mechanisms through which states and other international actors realize their interests. Attention is paid to such components of modern diplomacy as large volumes of information and databases, e-government, e-participation, cyber security, and digital transformation. The article combines an analytical view of modern diplomacy with the disclosure of the conditions of the information age, which shape the directions and fundamental tasks of modern development. It was determined that transformations of power regarding the priority of production and control of value meaning and cultural codes of society, should be taken into account by digital diplomacy, with the involvement of a wide range of subjects from both the state and non-state spheres. The article is devoted to the specific issues of challenges to political decision-making processes in the field of digital diplomacy: virtualization of social and political processes, the state of uncertainty, instability, fluidity in the global space, latency, uncoordinated influence of centers of power (power), the circle of which has significantly expanded, the struggle for informational dominance, for reducing the information space and opportunities of opponents.

The authors note that knowledge, values, cultural codes of societies, communication channels, new media, and information networks are becoming strategically significant in international activities.

Since the new quality of power is that it increasingly gets rid of institutional localization, anonymity, network flexibility, capacity for non-linear policy-making, principles of horizontality and verticalism, taking into account the tasks of the unstable balance of the principles of horizontality and verticalism, strategic and tactical, priority and conjunctural tasks, axiological meanings, and competitive images give modern actors of world politics great advantages.
TRUST IN THE AUTHORITIES IN THE CONDITIONS OF A FULL-SCALE MILITARY INVASION OF THE RF INTO UKRAINE: ALL-UKRAINIAN AND KHARKIV URBAN DIMENSIONS
Authors: Avksentiev Anton
Published: February 2025

The article is devoted to determining the dynamics of trust in the authorities in the conditions of a full-scale military invasion of the Russian Federation into Ukraine. Based on the material of All-Ukrainian sociological surveys, trends in the level of trust in the President of Ukraine and approval of the direction of the state of affairs in the country during 2022-2024 were analyzed. The dynamics of trust in the Kharkiv mayor and approval of the direction of the state of affairs in the city were analyzed on the basis of municipal sociological surveys. It is argued that the rapid growth of support for the president and the general positive assessment of the direction of the state of affairs in the country after the full-scale military invasion of the Russian Federation in Ukraine in 2022 is relevantly explained within the framework of the political science concept «rally-round-the-flag». The article reveals the content of this concept, which establishes a direct cause-and-effect relationship between the emergence of an extremely high-level security threat to the state and society and a time-limited increase in trust in the government and support for its course. It was found that after the initial rapid growth of trust in the President of Ukraine and his course in 2022, a downward trend in the dynamics of public support is observed. It was noted that after two years of the full-scale military invasion of the Russian Federation in Ukraine, the majority of citizens stopped positively evaluating the direction of the state of affairs in the country – this moment was characterized as the end of the «rally-round-the-flag» in the All-Ukrainian dimension regarding the support of the government and its course. It has been proven that the «electoral beneficiary» of the «rally-round-the-flag» caused by the war can be not only the central government and the president personally, but also local government representatives (in particular, the mayor of a front-line regional center). It is emphasized that longer manifestations of the «rally-round-the-flag» effect at the level of a local community (in particular, regarding trust in local authorities and positive assessments of the situation in the city) can be explained by the continuously high intensity of the external threat to residents.
GENERAL CHARACTERISTICS OF THE POST-SOVIET SPACE POLITICAL REGIMES AND FEATURES OF THEIR FORMATION
Authors: Koshelnyk Vladyslav
Published: February 2025

The main characteristics and features of the political regimes of the post-Soviet Baltic states, Ukraine, Russia and Georgia are considered and determined in the context of their transformation after the collapse of the USSR. The focus is on different ways of democratization in these countries, which were reflected in constitutional changes, ideological narratives, and foreign policy. The hybridity of political regimes in the transition period, when the political and economic modernization of breeds with the tasks of preservation and development of national identity took place, is explained. The multi-vector nature of political changes in post-Soviet countries is considered, which was manifested in different results of reform efforts - from democratization to authoritarianization, caused by the reaction to internal challenges and the need to adapt to international norms. Certain remnants of Sovietism and bureaucratic elements that inhibit the process of transformation and democratization are analyzed, which allows them to be labeled as neo-patrimonial: centralization of power, dominance of one party in the management of the state or a narrow group of persons, which negatively affects the formation and development of civil society and, in general, the process democratization. Two tables have been compiled, which trace the evolution of constitutions, economy, ideology and political systems in post-Soviet countries and the evolution of political regimes in post-Soviet countries, taking into account the influence of international organizations. The determined specificity of the Ukrainian political system shows certain differences from other post-Soviet countries.
POLITICAL CARICATURE AS AN ELEMENT OF RUSSIA'S HYBRID WAR AGAINST UKRAINE (2014-2022)
Authors: Gaiko Oleg , Chaika Oksana
Published: February 2025

The article deals with the political caricature of Russia in the Russian-Ukrainian war (2014-2022). It is shown that since 2014, Russia has systematically and consistently implemented a hybrid war against Ukraine, in which political actions were more important than military actions. The authors emphasize such an important element of the hybrid war against Ukraine as the implementation of the so-called "Gerasimov Doctrine" as evidence of the transformation of wars in 21st century.

The main features and main objectives of Russian political caricature, as well as some approaches to hybrid warfare, are analyzed, and the main ideological narratives of Russian political caricature as an element of Russia's hybrid war against Ukraine (2014-2022) are highlighted. The role of social networks as a convenient tool for the dissemination of Russian political caricature is revealed. It is shown that political caricature was one of the important elements of Russia's political propaganda in the context of the Russian-Ukrainian war of 2014-2022. The basic features and main tasks of Russian political caricature in Russia's hybrid war against Ukraine are considered, the main features and main tasks of Russian political caricature aimed at forming the desired emotional reaction are highlighted. The main ideological narratives of Russian political caricature during the Russian-Ukrainian war (2014-2022) are traced. The authors analyze the reaction of Russian political propaganda (on the example of political caricature) to the statements of the international community regarding Russia's actions in the Russian-Ukrainian war. It is shown that the Russian political caricature was quite effective and promptly responded to political challenges (especially to the reactions of the international community to Russia's actions in the Russian-Ukrainian war).