bluuebunny/crossref_metadata_2025 huggingface dataset:
A Textbook Pointing the Way to the Russian Classics
Authors: Yakovenko Natalya V.
Published: March 2021

The article is a review of the textbook in two parts under the title “Russian literature of the 19th century” by the well-known literary scholar Doctor of Philology Yuri Vladimirovich Lebedev. A brief description of the publication, its structure, some of the problems raised by the author, and the basic concept of the textbook continuing the whole line of the author's books published for schoolchildren and students are given. Yu. V. Lebedev emphasizes the uniqueness of the path of Russian literature, a special mission that has always been with our writers — to be spiritual authorities, especially in the most difficult times of our country. In this textbook presents not only the personalities of poets and writers. The author of the textbook also shows the integral literary process of the 19th century closely connected with philosophical thought in Russia and the life of society. In his textbooks Yu. V. Lebedev for the first time in the post-reform period in Russia speaks so vividly and accurately about the reviving and transforming power of Russian classical literature.
Artist and Authorities. Nikolay Gogol and the Censorship Policy of the 19th–20th Centuries
Authors: Vinogradov Igor' A.
Published: March 2021

The article is devoted to historical and theoretical problems of relations between an artist and the authorities. The work summarizes old methodological principles for studying Russian censorship in the 19th century and formulates the new ones. A comprehensive study of the censorship histories of N. V. Gogol's works introduces significant adjustments to the idea of the exclusively negative role of censorship in his literary fate, and proves the overall positive interaction with the censorship department. The author analyzes the limitations of the "class approach" inherited from the past era in the understanding and assessment of censorship, which in fact represents a system of regulatory norms and restrictions. The social significance of the institution of censorship as the most important component of culture is emphasized. Despite the well-known shortcomings of the censorship department in the 19th century, which was exclusively covered by the radical criticism, Russian censorship was at the forefront of the struggle against negative processes that developed in the subsequent 20th century. The character of Gogol's satire as a form of public service is studied. The correlation of spiritual and pastoral denunciation with state interests is considered among other censorship issues.
The Notes of Different Years’ of the Moscow Merchant Pyotr Porokhovshchikov: a Family Chronicler in a historical Miscellanea of the Second Half of the 18th century
Authors: Poliakov Ivan A. , Smirnova Maria A.
Published: March 2021

The article focuses on the family chronicler of the Moscow merchants Porokhovshchikovs,Abstract: The article focuses on the family chronicler of the Moscow merchants Porokhovshchikovs,discovered in the collection of A. A. Titov in the Manuscripts Departmentof the National Library of Russia. The handwritten Notes are located on the last pages of thehistorical miscellanea of the second half of the 18th century. Annual records were kept from1753 to 1803 first by Petr Isaevich, and then by his son Andrey Petrovich Porokhovshchikovs.The article reflects the history of the creation of The Notes, makes observations aboutthe tradition of keeping such chroniclers in the merchant environment of the second half ofthe 18th — early 19th centuries in general, and in the Porokhovshchikovs family in particular.The authors traced the reflection of the author’s “social circles” in the text of The Notes. Thearticle precedes the commented edition of the monument, which will be published in thenext issue of the journal.
Mitral valve repair versus replacement with extensive annular calcification: a systematic review and meta-analysis
Authors: Baudo Massimo , Petruccelli Rocco , Muneretto Claudio
Published: March 2021

Background: Mitral annular calcification (MAC) represents an important
risk factor in mitral valve (MV) surgery. Despite several procedures
have been described, no surgical treatment of choice has been yet
established. Materials and Methods: A systematic review of the
literature and meta-analysis on patients undergoing MV surgery
associated to MAC was performed. The meta-analysis primary endpoints
were 30-day mortality and late overall and cardiac-related mortality.
Secondary endpoints were early reintervention, re-exploration for
bleeding, postoperative pacemaker implantation, cerebrovascular
accident, atrioventricular groove rupture, acute myocardial infarction
and late recurrences of mitral regurgitation (MR) or paravalvular leak
and reintervention. Primary and secondary endpoints were also evaluated
in the subgroup analysis between MV repair and replacement surgery.
Meta-regression was used to analyze the influence of decalcification and
annular reconstruction on endpoints. Results: Among 1429 papers, 25
papers studying 1327 patients were included. In the pooled analysis, the
30-day mortality event rate was 2.89% (95%Confidence Interval
[CI], 1.48%-5.57%) and 7.72% (95%CI, 2.95%-18.71%) for MV
repair and replacement respectively. At mid-term follow-up, MV repair
revealed a significantly lower incidence rate (IR) of death compared to
MV replacement (p=0.043), with a trend of higher reoperation IR compared
to replacement (p=0.051) and a trend of higher recurrent MR2+ in MV
repair (p=0.071). Annular reconstruction was associated with a
significant increase in re-exploration for bleeding at univariate
analysis, but not at the multivariate meta-regression. Conclusions: The
current meta-analysis suggests that MV repair in MAC patients may
provide better short and mid-term survival outcomes when compared to
replacement.
Clinical course of thoracic mycotic aneurysm in a patient who was rescued by thoracic endovascular aortic repair with video-assisted thoracic surgery after rupture
Authors: Kim Yun Seok
Published: March 2021

Ruptured thoracic mycotic aneurysm is fatal, and surgical resection of
the aorta may be unavailable because of occurrence of preoperative shock
in such a patient. In the present case, the thoracic mycotic aneurysm
ruptured during hospital stay, causing acute hypovolemic shock but was
successfully repaired by thoracic endovascular aortic repair (TEVAR)
with video-assisted thoracic surgery (VATS) drainage.
left ventricular apex rupture in STEMI
Authors: Mohamed Amr
Published: March 2021

Mechanical complications of myocardial infarction are rare. However, the
consequences are catastrophic if missed; here, we present a case
highlighting the red flags that can guide the diagnosis of mechanical
complications of MI.
COVID-19 CARDIAC ARREST DUE TO PRINZMETAL'S ANGINA IN A PREVIOUSLY NORMAL HEART
Authors: Wang Melinda , Talon Andrew , Saririan Mehrdad
Published: March 2021

There has been a compelling body of evidence of COVID-19 causing cardiac
complications such as myocarditis and increased risk of coronary
thrombosis. Acute coronary syndrome due to coronary vasospasm is an
unusual occurrence.
Surgical management of a giant congenital left ventricular aneurysm in a 2-month-old infant.
Authors: Egunov Oleg , Krivoshchekov Evgeniy , Cetta Frank , Sviazov Evgenii , Sokolov Alexander
Published: March 2021

This clinical case demonstrated surgical management of a giant
congenital left ventricular aneurysm in a 2-month-old female using the
Dor procedure. Transthoracic echocardiography performed at 6-month
follow-up showed an ejection fraction of 66%.
A 52-year-old man with asymptomatic giant thoracic-abdominal aortic aneurysm
Authors: Deng Jianying , Liu Wei
Published: March 2021

A 52-year-old man was admitted to our hospital for “CT-diagnosed
thoracic-abdominal aortic aneurysm”. One week ago, the patient had
repeated dry coughs and went to the local hospital for treatment. A
chest radiograph revealed a huge mass in the left thoracic cavity. A
further chest CT examination revealed a thoracic-abdominal aortic
aneurysm and was transferred to our hospital for surgical treatment.The
patient is almost healthy, with no fever, no severe chest and abdomen
pain, no dyspnea, no dysphagia or other clinical symptoms. Ten years
ago, the patient underwent “ascending aorta and total aortic arch
replacement surgery” in another cardiovascular hospital due to aortic
dissection involving the ascending aorta and aortic arch (Debakey I).The
patient’s thoracic-abdominal aortic aneurysm is huge and has a high risk
of rupture. Recently, the patient has undergone thoracic-abdominal
aortic replacement surgery and is recovering well.
Moxibustion for Chronic Pelvic Inflammatory Disease：A systematic review and meta-analysis
Authors: Hua Fanghui , Xiong Jun , Huang Shouqiang , Xiang Jie
Published: March 2021

Background: This study was performed to strictly evaluate the quality of
RCTs and thus test the effect of moxibustion on CPID. Methods: Seven
databases (PubMed, Cochrane Library, Embase, China National Knowledge
Infrastructure, WangFang Database, Chinese Scientific Journal Database,
Chinese Biomedical Literatures Database were reviewed for RCTs on CPID
treated by moxibustion up to September 2020. Methodological quality and
evidence level was assessed on the basis of the RoB tool from Cochrane
collaboration and the GRADE instrument, respectively. RevMan5.4.1 and
Stata 12.0 software were used for further meta-analysis.Results: A total
of 17 RCTs were included (1315 participants, 515 treated by moxibustion
and 515 treated by control therapy). The meta-analysis showed that, in
comparison to control group, moxibustion had a higher total effective
rate (RR = 1.21; 95% CI [1.31, 1.29]; P = 0.007; I2 = 53%); and
lower total symptom score (MD = -3.72; 95% CI [-4.38, -3.06]; P
=0.02; I2 = 66%). As for the total sign score, the participants treated
by moxibustion had lower scores than those treated by control
therapy(SMD = -0.72; 95% CI [ -1.07, -0.37]; P = 0.36; I2 = 0%).
For the VAS score, pelvic fluid and inflammatory factor level, only one
trial showed that there was a significant effect, respectively.
Conclusions: This study shows that moxibustion is more effective and
safe for CPID. The findings we obtained must be interpreted with caution
due to universal low quality and low evidence level of the eligible
trials.
Reg3g ameliorates Tacrolimus-induced pancreatic β cell dysfunction by restoring mitochondrial function
Authors: Xiang Ming , Li Senlin , Zhou Hong , Xie Mengyuan , Zhang Zijun , Gou Jing , Yang Jian , Tian Cheng , Ma Kun , Lu Yi , Li Qing , Peng Wen
Published: March 2021

Background and Purpose: Tacrolimus (Tac) induces pancreatic β cell
dysfunction, causing new-onset diabetes mellitus (NODM) after
transplantation. Reg3g is a member of the pancreatic regenerative gene
family, as reported to improve type 1 diabetes by promoting β cell
regeneration. Here, we aim to investigate the role and approach of Reg3g
in reversing Tac-induced β cell dysfunction and NODM in mice.
Experimental Approach: Circulating REG3A (the human homolog of mouse
Reg3g) concentrations of patients treated with Tac after heart
transplantation(HT) were detected. The glucose-stimulated insulin
secretion (GSIS) and mitochondrial functions, including mitochondria
membrane potential (MMP), mitochondria calcium uptake, ATP production,
and oxygen consumption rate (OCR), were tested in β cells. Effects of
Reg3g on Tac-induced NODM in mice were studied. Key Results: Circulating
REG3A levels significantly decreased in NODM patients treated with Tac
compared with those without diabetes. Tac down-regulated Reg3g via
inhibiting STAT3-mediated transcription activation, while Reg3g
protected against Tac-induced apoptosis of β cells. Besides, Reg3g
restored GSIS suppressed by Tac in β cells via improving mitochondrial
function, including increased MMP, mitochondria calcium uptake, ATP
production, and OCR. Mechanically, Reg3g increased accumulation of
pSTAT3(Ser727) in mitochondria by activating ERK1/2-STAT3 signaling
pathway, leading to restoration of Tac-caused mitochondrial impairment.
Moreover, Reg3g overexpression effectively ameliorated Tac-induced NODM
in mice. Conclusion and Implications: Reg3g ameliorates Tac-induced
pancreatic β cell dysfunction by restoring mitochondrial function via a
pSTAT3(Ser727)-dependent way. Our observations identify a novel
Reg3g-involved mechanism underlying the augmented incidence of
Tac-induced NODM and reveal that Reg3g ameliorates Tac-induced β cell
dysfunction.
OPTIMAL DECAY RATES OF A NONLINEAR SUSPENSION BRIDGE WITH MEMORIES
Authors: Afilal Mounir , Feng Baowei , Soufyane Abdelaziz
Published: March 2021

In this paper, we investigate the decay properties of suspension bridge
with memories in one dimension. To prove our results, we use the energy
method to build some very delicate Lyapunov functionals that give the
desired results.
Attenuation of Sinapic Acid and Sinapine-Derived Flavor-Active Compounds Using A Factorial-Based Pressurized High-Temperature Processing
Authors: Nandasiri Ruchira , Zago Erika , Thiyam-Holländer Usha , Eskin Michael
Published: March 2021

De-oiled canola meals are sources of protein-containing flavor-active
phenolic compounds. Conventional canola oil processing utilizes an
excess amount of solvents and is associated with the release of
high-intensity bitter flavor-active phenolic compounds, limiting the use
of the canola meal. Recent advances in the extraction and isolation of
the bitter favor-active phenolic compounds from canola by-products
produce protein isolates, however, would benefit the industry by
producing a side-stream ingredient rich in phenolics. High temperature
and pressure-aided processing, namely the accelerated solvent extraction
(ASE) was investigated to extract the flavor-active bitter molecules
from the canola meal. The extractability of flavor-active phenolic
compounds including the major sinapates, kaempferol derivatives, and
other thermo-generative compounds including thomasidioc acid (TA) was
evaluated. The effects of temperature, solvent extractant and
concentration, and the particle size of the meal, were examined on the
extraction efficiency of these phenolic compounds. Extraction
temperature (180oC) was the primary determinant (p<0.05) for
the attenuation of major sinapates including sinapine and sinapic acid.
Both ethanol and methanol extractants at a concentration of 70% (v/v)
significantly (p<0.05) extracted the flavor-active phenolic
compounds. The pressurized high temperature through optimized ASE
conditions attenuated the bitter undesirable flavor-active phenolic
molecules from canola meal thereby facilitating a potential value-added
phenolic-rich by-product.
The role of IgE, IgG, and IgA in tolerance, sensitization, and targeted treatment of allergic disease
Authors: Shamji Mohamed , Valenta Rudolf , Jardetzky Theodore , Verhasselt Valerie , Durham Stephen , Würtzen Peter , Neeven R.J.Joost van
Published: March 2021

Immunoglobulin E (IgE)-mediated allergy is the most common
hypersensitivity disease affecting more than 30% of the population. In
genetically-predisposed subjects exposure to minute quantities of
allergens leads to the production of IgE antibodies which is termed
allergic sensitization and mainly occurs in early childhood.
Allergen-specific IgE then binds to the high (FcRI) and low affinity
receptors (FcRII, also called CD23) for IgE on effector cells and
antigen-presenting cells, respectively. Subsequent and repeated allergen
exposure increases allergen-specific IgE levels and, by receptor
cross-linking, triggers immediate release of inflammatory mediators from
mast cells and basophils whereas IgE-facilitated allergen presentation
perpetuates T cell-mediated allergic inflammation. Due to engagement of
receptors which are highly selective for IgE even tiny amounts of
allergens can induce massive inflammation. Naturally occurring
allergen-specific IgG and IgA antibodies usually recognize different
epitopes on allergens compared to IgE, and do not efficiently interfere
with allergen-induced inflammation. However IgG and IgA antibodies to
these important IgE epitopes can be induced by allergen-specific
immunotherapy or by passive immunization. These will lead to competition
with IgE for binding with the allergen and prevent allergic responses.
Similarly, anti-IgE treatment does the same by preventing IgE from
binding to its receptor on mastcells and basophils. Here we review the
complex interplay of allergen-specific IgE, IgG and IgA and the
corresponding cell receptors in allergic diseases and its relevance for
diagnosis, treatment and prevention of allergy.
Impact of the Environmental Management System Standardization on the Managerial Image of Firms: An Empirical Study
Authors: Garechana Gaizka , Río-Belver Rosa , Zarrabeitia-Bilbao Enara , Álvarez-Meaza Izaskun
Published: April 2021

We describe a characterization of the conceptual and emotional changes on environmental issues in a sample of firms certified under the ISO 14001 standard. Business communications regarding the main Spanish industrial firms have been downloaded from the ABI/INFORM database and processed using Vantage Point software, in order to study the evolution of the main concepts and emotions before and after the certification year. Our study concludes that in the years before certification, environmental management was fundamentally tied to operative issues, broadly pivoting on the immediate impact of a firm's productive activities. Environmental management gains strategic traction in the years after certification, positioning itself near corporate decision-making concepts and associated with adjectives that denote relevance and positivity. The sentiment analysis points at an increased positivity of environment-related issues, accompanied by a general decrease in negative emotions and an increased presence of expectation and planning emotions.
Managers' Equity Incentives and Asymmetric Cost Behavior
Authors: Brisker Eric R. , Park Jong Chool , Song Hakjoon
Published: April 2021

Recent research documents the phenomenon of sticky cost behavior where costs change asymmetrically between an increase and a decrease in sales and attributes this behavior to managers' deliberate decisions. In this paper, we test the relationship between sticky cost behavior and equity incentives. We find that a measure of the sensitivity of managerial wealth to stock price (delta) is positively related to sticky costs where costs increase more quickly in response to a sales increase than they decline in response to a sales decrease. Conversely, we find that a measure of the sensitivity of managerial wealth to stock volatility (vega) is positively related to anti-sticky costs where costs increase to a lesser extent in response to a sales increase than they decline in response to a sales decrease. These results indicate the importance that equity incentives have on managerial resource adjustment decisions in response to changes in firm activity levels.

JEL Classifications: G32; G34.
Implementasi Strategi Komunikasi Guru (SKG) dalam Pembelajaran untuk Meningkatkan Hasil Belajar Bahasa Inggris
Authors: Sumarni Ni Nengah
Published: March 2021

Penelitian ini bertujuan untuk mengetahui peningkatan aktivitas dan hasil belajar siswa kelas XI TO.1 Semester 1 SMK Negeri 2 Negara setelah diterapkan Implementasi Strategi Komunikasi Guru pembelajaran dalam pembelajaran Bahasa Inggris. Subjek penelitian ini adalah siswa Kelas XI TO.1 SMK Negeri 2 Negara sebanyak 36 orang yang terdiri dari 36 orang siswa laki-laki. Dipilihnya siswa. Yang dijadikan objek penelitian ini adalah kemampuan belajar Bahasa Inggris siswa Kelas XI TO.1 SMK Negeri 2 Negara yang masih rendah. Kemampuan belajar Bahasa Inggris dipilih sebagai objek penelitian yang akan diperbaiki mengingat kemampuan dalam pembelajaran Bahasa Inggris sangat penting dikuasai oleh siswa dalam menguasai kemampuan mata pelajaran lainnya. Indikator keberhasilan penelitian tindakan ini adalah bila terjadi peningkatan aktifitas belajar dan hasil belajar siswa yang dihitung berdasarkan prosentase pada setiap siklusnya. Kriteria hasil belajar siswa menggunakan rata-rata tes ulangan harian. Berdasarkan hasil penelitian diperoleh kesimpulan bahwa melalui Implementasi Strategi Komunikasi Guru (SKG) dalam pembelajaran Bahasa Inggris siswa kelas X TO.1 Semester 1 SMK Negeri 2 Negara ternyata dapat meningkatkan aktivitas dan hasil belajar siswa. Peningkatan aktivitas dapat terlihat dari nilai rata-rata pra siklus sebesar 48,46 %, di siklus I sebesar 67,59% dan siklus II sebesar 87,96%. Sedangkan peningkatan aktivitas kinerja kelompok pra siklus ke siklus I meningkat rata-rata 15,56 % dan siklus I ke siklus II meningkat 20,20 % dengan rata-rata pada siklus II kinerja kelompok sudah dikatakan baik karena mencapai rata-rata 89,25. Analisis hasil belajar siswa diperoleh melalui hasil evaluasi setelah dilaksanakan tindakan yang dilakukan setiap siklus. Peningkatan hasil belajar siswa terlihat dari jumlah siswa yang tuntas belajar pada pra siklus 63,9%, siklus I sebesar 88,9%, dan siklus II siswa yang tuntas mencapai 97,2%.
PENERAPAN MODEL PEMBELAJARAN LEARNING CYCLE “5E” UNTUK MENINGKATKAN MOTIVASI DAN PRESTASI BELAJAR KOMUNIKASI INDUSTRI PARIWISATA
Authors: Aryantini Ni Putu
Published: March 2021

Penelitian ini dilaksanakan dalam dua siklus pembelajaran di kelas X AP1  SMK Negeri 2 Singaraja pada semester genap tahun pelajaran 2019/2020 yang terdiri atas 40 orang siswa. Penelitian ini bertujuan untuk meningkatkan motivasi dan prestasi belajar Komunikasi Industri Pariwisata siswa. Data motivasi belajar siswa dikumpulkan dengan menggunakan lembar angket/kuisioner. Data prestasi belajar siswa diperoleh dengan menggunakan nilai tes prestasi belajar. Metode analisis datanya adalah deskriptif baik untuk data kualitatif maupun data kuantitatif. Hasil penelitian ini menunjukkan bahwa Penerapan Model Pembelajaran Learning Cycle “5E” dalam pembelajaran Komunikasi Industri Pariwisata dapat meningkatkan motivasi dan prestasi belajar siswa. Ini terbukti dari hasil yang diperoleh dimana motivasi belajar siswa meningkat sebesar 6,88 dari rata-rata 41,35 dengan kategori tinggi pada siklus I  menjadi 48,23 dengan kategori sangat tinggi pada siklus II  dan prosentase keberhasilan meningkat sebesar 39% dari 48 % pada siklus I  menjadi 87 %  pada siklus II dan prestasi belajar siswa meningkat sebesar 0,74 dari rata-rata 7,25 pada siklus I menjadi 7,99 pada siklus II, daya serap (DS) siswa meningkat sebesar 7,4 % dari 72,5 % pada siklus I menjadi 79,9 % pada siklus II, ketuntasan belajar (KB) siswa meningkat sebesar 14% dari 83 % pada siklus I menjadi 97 % pada siklus II.  Kesimpulan yang diperoleh dari penelitian ini adalah Penerapan Model Pembelajaran Learning Cycle “5E” dalam pembelajaran Komunikasi Industri Pariwisata dapat meningkatkan Motivasi dan Prestasi Belajar Komunikasi Industri Pariwisata Siswa Kelas X AP1 SMK Negeri 2 Singaraja Semester Genap Tahun Pelajaran 2019/2020.
Penerapan Model Pembelajaran Direct Learning untuk Meningkatkan Hasil Belajar Mata Pelajaran Food And Beverage Pada Kompetensi Menerapkan Tehnik Platting dan Garnish
Authors: Supartini Komang Wiwik
Published: March 2021

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar mata pelajara Food And Beverage pada kompetensi menerapkan tehnik Platting dan Garnish siswa kelas XI Perhotelan 4 semester genap SMK Negeri 2 Singaraja tahun pelajaran 2019/2020 setelah diterapkannya model pembelajaran Direct Learning. Penelitian ini adalah penelitian tindakan kelas. Subjek penelitian ini adalah siswa kelas XI Perhotelan 4 SMK Negeri 2 Singaraja yang berjumlah 40 siswa. Sedangkan yang menjadi objek penelitian ini adalah peningkatan hasil belajar Food And Beverage kompetensi Menerapkan Tehnik Platting dan Garnish setelah menggunakan model pembelajaran Direct Instruction dalam proses pembelajaran. Metode pengumpulan data menggunakan metode observasi. Sedangkan metode analisis data menggunakan metode analisis deskriptif. Penelitian Tindakan Kelas ini dikatakan berhasil apabila seluruh siswa dalam mata pelajaran Food And Beverage kompetensi Menerapkan Tehnik Platting dan Garnish mendapatkan nilai KKM 80 dengan prosentase 100%. Hasil penelitian ini menunjukkan bahwa terdapat peningkatan hasil belajar siswa terhadap penerapan model pembelajaran Direct Instruction (Pembelajaran Langsung) khususnya pada pelajaran Food And Beverage kompetensi Menerapkan Tehnik Platting dan Garnish yaitu 78,08 pada siklus 1 dan 83,38 pada siklus 2 atau dari 37,50 % menjadi 92,50%. Hal ini menunjukkan peningkatan yang signifikan sebesar 55%.
Is place or person more important in determining higher rural cancer mortality? A data-linkage study to compare individual versus area-based measures of deprivation
Authors: Murchie Peter , Fielding Shona , Turner Melanie , Iversen Lisa , Dibben Chris
Published: April 2021

Data from Northeast Scotland for 11,803 cancer patients (diagnosed 2007-13) were linked to UK Censuses to explore relationships between hospital travel-time, timely-treatment and one-year-mortality, adjusting for both area and individual-level socioeconomic status (SES). Adjusting for area-based SES, those living >60 minutes from hospital received timely-treatment more often than those living <15 minutes. Substituting individual-level SES changed little. Adjusting for area-based SES those living >60 minutes from hospital died within one year more often than those living <15 minutes. Again, substituting individual-level SES changed little. In Northeast Scotland distance to services, rather than individual SES, likely explains poorer rural cancer survival.
Background and objectiveThe Northeast and Aberdeen Scottish Cancer and Residence (NASCAR) study found rural-dwellers are treated quicker but more likely to die within a year of a cancer diagnosis. A potential confounder of the relationship between geography and cancer mortality is socioeconomic status (SES). We linked the original NASCAR cohort to the UK Censuses of 2001 and 2011, at an individual level, to explore the relationship between travel time to key healthcare facilities, timely cancer treatment and one-year mortality adjusting for both area and individual-level markers of socioeconomic status.
MethodsA data linkage study of 11803 patients examined the association between travel times, timely treatment and one-year mortality with adjustment for area, and for individual-level, markers of socioeconomic status.
ResultsFollowing adjustment for area-based SES measures those living more than 60 minutes from the cancer treatment centre were significantly more likely to be treated within 62 days of GP referral than those living within 15 minutes (Odds Ratio [OR]) 1.41; 95% (Confidence Interval [CI]) 1.23 , 1.60]. Replacing area-based with individual-level SES measures from UK Censuses made little impact on the results [OR 1.39; 95% CI 1.22, 1.57].
Following adjustment for area-based SES measures of socioeconomic status those living more than 60 minutes from the cancer treatment centre were significantly more likely to die within one year than those living closer by [OR 1.22; 95% CI 1.08, 1.38]. Again, replacing area-based with individual-level SES measures from UK Censuses made little impact on the result [OR 1.20; CI 1.06, 1.35].
ConclusionsDistribution of individual measures of socioeconomic status did not differ significantly between ruraland urban cancer patients. The relationship between distance to service, timely treatment and one-year survival were the same adjusting for both area-based and individual SES. Overall, it seems thatdistance to services, rather than personal characteristics, influences poorer rural cancer survival.
Maternal and perinatal outcomes in women with advanced maternal age affected by SARS-CoV-2 infection (Phase-2): The WAPM (World Association of Perinatal Medicine) Working Group on COVID-19
Authors:   WAPM Working Group on COVID-19, D'Antonio Francesco , Şen Cihat , Di Mascio Daniel , Galindo Alberto , Villalain Cecilia , Herraiz Ignacio
Published: March 2021

Objective To elucidate the role of advanced maternal age (AMA) in determining the outcome of pregnancies complicated by SARS-CoV-2 infection. Methods Multinational cohort study included women with laboratory-confirmed SARS-CoV-2 infection from 76 centers in 27 different countries in Europe, United States, South America, Asia and Australia from 04 April 2020 till 28 October 2020. The primary outcome was a composite measure of maternal mortality and morbidity including admission to intensive care unit (ICU), use of mechanical ventilation (defined as intubation, need for continuous positive airway pressure, extra-corporeal membrane oxygenation), severe respiratory symptoms (including dyspnea and shortness of breath) or death. Results Eight hundred and eighty seven pregnant women were included in the study who were positive SARS-CoV-2 results by RT-PCR (reverse transcriptase-polymerase chain reaction) on their nasal and pharyngeal swab specimens (352 with and 652 with no AMA). The risk of composite adverse maternal outcome was higher in AMA group compared to that of under 35 years of age group, with an OR of 1.99 (95% CI 1.4–2.9; p=0.002). Likewise, women >35 years were also at higher risk of hospital admission (OR: 1.88, 95% CI 1.4–2.5; p<0.001), presence of severe respiratory symptoms (OR: 1.53, 95% CI 1.0–2.3; p=0.04) and/or admission to ICU (OR: 2.00, 95% CI 1.1–3.7; p=0.003); however, no difference was observed in terms of perinatal outcome risk. Conclusion Advanced maternal age is an independent risk factor for adverse maternal outcome in pregnancies complicated by SARS-CoV-2 infection. Accurate risk stratification of women presenting with suspected SARS-CoV-2 infection in pregnancy is warranted in order to identify a subset of women who may benefit from a personalized management, including elective hospitalization and/or prolonged surveillance in order to improve maternal outcome.
Corporate Governance and Financial Fraud of Wirecard
Authors: Jo Hoje , Hsu Annie , Llanos-Popolizio Rosamaria , Vergara-Vega Jorge
Published: March 2021

This paper examines the antecedents and consequences of the collapse of Wirecard AG, in June 2020, the “German Enron.” Specifically, we investigate how the Wirecard’s ineffective corporate governance under the German’s financial regulatory system fails to serve their stakeholders, and how its management’s unethical behavior of earnings manipulation contribute to significant financial collapse for the company, and lead to the destruction of shareholders’ value. This paper examines how the internal and external governance and monitoring mechanisms failed to uncover the vast fraud at the German payments group at a much earlier stage. Furthermore, we find evidence consistent with the hypothesis that the continuous pressure of meeting or exceeding consensus on earnings estimates, management’s performance compensation based on the growth of Wirecard’s stock price, and the lack of proper supervision from the board of directors ultimately create the opportunities for management to manipulate earnings without being uncovered for several years. Such course of action has caused significant financial corporate misconduct for Wirecard and led to the destruction of firm value.
Identification of Factors which Impact Towards Visit Intentions to Destination of Betawi Cultural Village Area
Authors: Safitri Aprilia , Astini Rina
Published: March 2021

This research aims to determine and analyze those factors which influence the visit intentions to Betawi Cultural Village Tourism Area. This population was tourists who interested in visiting the tourist destinations of Betawi Cultural Village, while the sample in this research was 150 respondents. This research analyzed by Structural Equation Model (SEM) with assistance of LISREL 8.80 program to examine these hypotheses. The result shows that visit intention to Betawi Cultural Village Tourism Area was influenced by motivation to visit and image of destination, while eWOM did not impact the visit intention to Betawi Cultural Village Tourism Area.
Analysis of Propylene Glycol Raw Supplier Selection using the Analytic Hierarchy Process Method
Authors: Budiono Yusuf , Permana Dudi
Published: March 2021

The purpose of this research is to study the priority order of the criteria and sub-criteria that influence supplier selection and to find out which supplier or supplier of the best raw material, which best meets the criteria for selecting the supplier that should be selected. In this study only limited to 4 criteria, namely price, quality, warranty, and delivery. This research is a qualitative research using the calculation method used is the Analytic Hierarchy Process (AHP) method. The software used in using the Analytic Hierarchy Process (AHP) method is version 3.2 super decisions. The findings show that the price criterion is the most important priority for companies to pay attention to, followed by delivery, quality, and warranty criteria.
Cooperatives of Farmers in Oman
Authors: Balasa Adela P. , Al-Mashaikhi Ghadeer Saif Khamis , Fitri Abdul Rahman Noorol Shaiful
Published: March 2021

This study focuses on explaining the concept of farmers' cooperatives which contribute to raising the Omani economy, achieving security and food balance, and contributing to the eradication of poverty, hunger and unemployment. The aim of this paper is to find areas of deficiency concerning the implementation of farmer cooperatives in Oman. The study follows the philosophy of realism, as it is delivering real and accurate information. The text uses a mixed method by combining qualitative and quantitative. The research uses questionnaire showing the responses of farmers and ordinary people to collect the data. In addition, an interview showing the importance and the factor of implementing farmer cooperatives. This study uses interviews and questionnaire to gather the data needed to fill the gaps. The findings of this research add deep discovery to the previous studies, regarding the unawareness and knowledge among farmers about the importance, causes and positive effects of cooperatives among farmers and the negative effects that may occur to farmers for refusing to enter farmers' cooperatives and the factors of implementing farmer’s cooperatives. Additional research in this topic is needed for full understanding of making strong relationships and trust between farmers, which convince them to join farmers' cooperatives. The value of this study lies in raising the level of farmer's cooperatives in Oman because of its invaluable role in improving livelihoods, achieving sustainable development, increasing profitability and increasing productive efficiency by finding the common reasons that prevent farmers to join these cooperatives.
The Relationship Between Cat Bond Market and Other Financial Asset Markets: Evidence from Cointegration Tests
Authors: Mouelhi Chaouki
Published: March 2021

This study examines the relationship between Cat Bonds market and the other financial markets. Precisely, cointegration tests (the Engle and Granger’s methodology) were applied on weekly data of five indexes over the period 2012- 2019 to test for the existence of a long-run dynamic equilibrium relationship between Cat Bonds market and four financial markets, namely, Insurance Linked Securities (ILS) market, S&P 500 (first stock market), MSCI (second stock market) and Corporate Bonds market. In addition, a comparative analysis correlation vs cointegration was conducted to verify whether Cat Bonds can be really considered as zero-beta assets in the short-run (correlation) as well as the long-run (cointegration). For correlation analysis we employed three correlation coefficients (Pearson’s Correlation Coefficient, Spearman’s Rank Correlation Coefficient and Kendall's Rank Correlation Coefficient). Overall, the main findings of this study showed that in the short-run, Cat Bonds are partially zero-beta assets while over the long-run they are entirely zero-beta assets. Such results will be of great importance for investors in their decision choice between a short strategy or a long strategy in Cat Bonds’ investing.
The Role of Intentions in Determining Social Entrepreneurial Profile
Authors: Meza Téllez María del Carmen , Ortiz Betancourt Ignacio , Villar Sánchez Patricia Margarita , López Castro Leidy Margarita , Muñoz Carrillo Jessica Andrea
Published: March 2021

In this research the entrepreneurial actions and intentions that drive university students to create social businesses and participate in an international competition were analyzed. The study was conducted during the training week of a social business competition in September 2019. The methodology was qualitative, with case studies in a group of twelve students whose projects were selected to compete at the semi-final round of an international social business competition. Interviews were applied to competitors which revealed the circumstances that encouraged them to address a social problem and develop a project with a solution which will be presented in an international stage. Simultaneously, an observation guide was applied for the interpretation of the emotional expressions (typical of social entrepreneurship) associated with their responses and finally, an electronic link was shared with participants for them to answer a validated instrument that measured the university entrepreneurial potential. Main findings indicate that entrepreneurial actions of the students to create a social business and present it in a competition in the form of a social business project rest on motives that vary from a personal origin to the collective, revealed from moments of inspiration and personal commitment to address a social problem and seeking a sustainable solution, designed from resources and personal skills in a very particular emotional atmosphere. Finally, a sum up from all inputs (surveys and direct observation) revealed that social entrepreneurial intentions lie on a positive attitude, strong enterprise convictions and high desirability for becoming an entrepreneur and contribute to solve social problems.
Entrepreneurship as a Mechanism to Strengthen Rural Communities
Authors: Ortiz Betancourt Ignacio , Meza Téllez María del Carmen , Villar Sánchez Patricia Margarita , López Castro Leidy Margarita , Berdón Carrasco Jorge Samuel
Published: March 2021

Entrepreneurship has positioned itself as one of the main goals of both public and private agencies. This topic has been linked to urban areas population, marginalizing different groups and sectors, including the inhabitants of the rural areas have been included, which, usually considered by their lower income and social welfare, due to their inability to access sources of employment and services. Then, this research parts from a theoretical review of rural entrepreneurship and subsequently, explores the results from the application of a research instrument, focused on the perception of a group of rural tourism entrepreneurs was measured about the scope of their projects, pointing out the faced barriers and the gains that have been produced in their communities.
Evaluation of the Profitability of Vegetable and Fruit Street Vendors in Mbombela Local Municipality in Mpumalanga Province, South Africa
Authors: Tshikhudo Lutendo Patrick , Manenzhe Teboho Derick
Published: March 2021

This paper evaluated the sustainability of fruits and vegetables street vendors in Mbombela Local Municipality using random and referral sampling method. The area was chosen because of its accessibility to the researchers and its potential to provide relevant and accurate information for the research project. Thus, a quantitative research method was used to collect data through face-to-face interviews. SPSS was employed as analytical tools. A higher percentage of females (66.7%) as against males (33.3%) were revealed from the analytical results. The household size of the majority (37%) had 2 persons per family among family households. The research discovered that some of the factors encouraging traders in the area ranged from making of enough profit and good quality of the wares. Furthermore, insufficient experience in business operations, non-adherence to municipal procedures for allocations of trading spaces and spots, theft, and lack of support from local municipality were identified as common challenges that might hamper trader’s sustainability.
Transeterification of a Mixture of Vegetable Fats with the Addition of Phytosterols
Authors: Honcharov D. S. , Tkachenko N. A. , Nikolaieva V. G.
Published: March 2021

Pure phytosterols that are sparingly soluble in oils were subjected to a transesterification reaction using the catalyst sodium methylate in a mixture of palm stearin: palm oil: sunflower oil. As a comparison, transesterification was performed under the same conditions without the addition of phytosterols. To determine the qualitative composition of the mixture transesterified with phytosterols, analyzes were performed on the fatty acid composition, sterol composition, and melting point. The resulting product differed from the control by the presence of a characteristic odor, sterol composition, melting point.
Reabilitação oral com coroa cerâmica fresada em CAD/CAM em dente com ampla destruição coronária – relato de caso
Authors: de Lima Andre Augusto Neves , Ribeiro Beatriz Bezerra , Santos Giovanna de Alcantara , Peris Alessandra Rezende , Mitsui Fabio Hiroyuki Ogata
Published: March 2021

The unitary ceramic crowns are fixed partial dentures cemented on the tooth to be rehabilitated and can be produced from CAD/CAM systems, a device that allows scanning the surface of interest, planning, and making the prosthetic part. The objective of this article is to report dental rehabilitation with the use of ceramic crown manufactured with the CAD/CAM system with the purpose of returning function, aesthetics, and well-being to the patient. Rehabilitation of tooth 26, already endodontically treated, was performed in two consultations, one for the temporary crown and the other for the definitive crown. The preparation for the total crown was done after filling the cavity with composite resin and then it was scanned with a scanner from the CEREC system (Dentsply Sirona). A temporary crown was designed in Cerec SW 4.6 software and then milled from a PMMA Vipiblock (VIPI) resin block. The model of the temporary piece was used to guide the preparation of the definitive crown milled from a leucite-reinforced ceramic block (Empress CAD Multi - Ivoclar) in color B1. After obtaining the crown, it was aesthetic finished to obtain greater naturalness. CAD/CAM system offers advantages in reducing the treatment time, in addition to manufacturing pieces that correctly adapt to the preparation margins and that have occlusal and proximal contact points at the appropriate intensity. It is important that work on methods and materials within dentistry are carried out constantly, keeping professionals updated.
Estabelecendo a oclusão lingualizada na reabilitação de pacientes edêntulos com próteses totais removíveis
Authors: Lidani Rangel , Sakurada Matheus Akira , Duarte Laís , Floriani Franciele , Philippi Analucia Gebler , Mezzomo Luis André Mendonça
Published: March 2021

This article describes the protocol with specific techniques for the establishment of a lingualized occlusion in the rehabilitation of edentulous patients with removable complete dentures.
Reabilitação total com porcelanas em paciente acometido por amelogênese imperfeita
Authors: Silva Weider de Oliveira , de Sá Gabriela Barbosa , Pinto Tarcísio , Montenegro Gil , Pinto Ismael Lucas
Published: March 2021

Amelogenesis imperfecta (AI) is a disorder of genetic origin, linked to the amelogenin gene, which presents developmental abnormalities in the quantity and quality of tooth enamel. The main clinical problems are the extensive loss of dental tissue, occlusal problems, impaired aesthetics, tooth sensitivity and gingival inflammation. This study described a clinical case and the approach in the treatment of a patient with AI, with gingival plastic surgery, porcelain crowns on the posterior teeth, porcelain veneers on the anterior teeth and application of botulinum toxin to correct the gingival smile. AI is an anomaly with complex development and early diagnosis is essential for the conduct and success of the case, to improve aesthetics and function, preserving the characteristic tooth wear.
Tratamento cirúrgico de fratura nasal vinte anos após o trauma
Authors: Santana Daiana Cristina Pereira , Garcia Juliana Jorge , Fialho Priscila Vital , dos Santos Marcelo Oldack Silva , Seixas Alexandre Martins
Published: March 2021

Nasal bone fractures are very common, and their approach should be immediate to better repair the defects. This is not always possible, which makes the surgical procedure more complex, often going from a simpler fracture reduction to a nose reconstruction. There are several materials and techniques to perform this type of procedure, among them the implant made from polymethyl methacrylate (PMMA). This study aimed to report a case of nasal dorsum reconstruction using a customized in situ molded PMMA prosthesis. A 24-year-old male patient searched for a public hospital with sequelae of fracture in his nasal bones, resulting from a mule kick twenty years ago, with aesthetic complaints. On physical examination, a significant loss of projection of the nasal dorsum was observed with local cicatricial fibrosis. To correct the defect, a prothesis constructed from PMMA was molded and installed, fixed with plates and screws. The patient has been under follow-up for one year with an acceptable result. Although it is not the first option in many cases for nasal dorsum reconstruction, PMMA can be used to repair existing sequelae areas, achieving satisfactory aesthetic results.
O impacto da autoimagem em crianças com estética odontológica comprometida – relato de casos
Authors: Damasceno Jéssica Mendes , Frota Lorena Vieira , Pinto Rafaella Alves Costa , Albuquerque Felipe Rezende , Pereira Neto Armando Rodrigues Lopes , Hanna Leila Maués Oliveira
Published: March 2021

During the development phase, the child is in the process of building human and social relationships. Smile aesthetics is an important point in the individual self-image and may interfere in his interaction with society and self-esteem. Thus, when smile harmony is impaired, the child’s self-image may be altered, promoting marks on her personality that may be perpetuated until adulthood. This case study analyzed the interference of dental rehabilitation in two children that had impaired aesthetics, qualitatively measuring through psychoanalysis, the impact that the aesthetics factor can have on self-image during the childhood. Psychological analysis and oral aesthetics rehabilitation were used as methodology, and rehabilitation varied according to the needs of each case. At the end of the treatment it was concluded that the aesthetics dental rehabilitation provided to these children development of psychic-emotional balance, enabling them a better social life.
Presença do canal mésio-vestibular 2 em primeiros molares superiores – série de casos
Authors: Lemes Letícia Tainá de Oliveira , Falcão Wellington Fernandes , Kich Tais , dos Santos Tiago Lange
Published: March 2021

The aim of this study was to report a series of clinical cases that show how the presence of the mesiovestibular 2 canal l(MV2) in the first maxillary molar is truly found. Patients complained of spontaneous pain with a history of element 26 or 16, some with deep caries and extensive restorations. Vertical and horizontal percussion tests, thermal tests. and radiographic analysis were performed. The canal was disinfected with abundant irrigation of 2.5% sodium hypochlorite. After, the root canals were located with files # 8 and #10, then the foraminal patency was performed with the EASY system file #25.01, root canal preparations were performed with EASY files from the Logic series #25.05, #40.05 and files #25.04, #30.03, #35.03. After using each file, irrigation with sodium hypochlorite was performed. After the canals were prepared, the cone test was carried out. After drying the canals, the final filling was performed with calibrated Tanari cones and AH plus cement. It was concluded that the occurrence of MV2 canal is high in the first maxillary molars and their location for disinfection is of paramount importance.