bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Brand Equity Drivers on Consumer-based Brand Equity in the Sport Service Setting
Authors: Gordon Brian S. , James Jeffrey D.
Published: May 2017

The importance of brand equity to a firm has been well documented by previous literature. Brands with high equity allow a firm to charge a premium price as well as garner a larger market share in relation to competitors (Simon & Sullivan, 1993). From the consumer’s perspective, previous research has failed to explain precisely how consumers perceive and become loyal to specific brands. Therefore, this study constructed and tested a consumer-based brand equity model based on Keller’s (2003a) brand equity pyramid that explains how consumer perceptions influence brand resonance. Data were collected from a general consumer sample (n = 787) in a mid-sized southeastern community in order to validate the consumer-based brand equity model. The results from an examination of the structural model confirmed a significant relationship between brand awareness and brand associations as posited by previous research. Brand associations were found to have a significant impact on a consumer’s cognitive evaluation (brand superiority) and affective response (brand affect) to a focal brand in the service realm. Further, this study highlighted the important role that emotions play in the process of building strong brand equity. Cumulatively, these findings revealed that two attitudinal constructs (brand superiority and brand affect) played a differential role in the brand association-brand resonance relationship in the services context.
Health related quality of life among children with Type I diabetes, Assiut city, Egypt
Authors: Gadallah Marzoka A. , Ismail Taghreed Abdul-Aziz M. , Abdel Aty Naglaa Saad
Published: May 2017

Objective: Health related quality of life (HRQOL) is a multidimensional construct that includes physical and psychosocial functioning, has emerged as an important outcome in pediatric population with chronic health conditions. The study objectives are to measure the quality of life among children with type I diabetes compared to healthy peers and to determine factors affecting the QOL among children with type I diabetes.Methods: Analytic cross sectional study was conducted in Sidi Galal health insurance outpatient clinic for children with type 1 diabetes mellitus and a comparison group of healthy peers was taken from other outpatient clinics. A total of four hundred and twelve children, aged from 8-18 years with type 1 diabetes and four hundred and twelve healthy peers matched in age and sex were interviewed. Three tools were used for this study: Demographic questionnaire, Socio-economic scale, and Peds QL4.0 Generic Core Scale was used to measure HRQOL.Results: The mean age of studied children was 12.9 ± 3.2. More than 60% of children with diabetes had uncontrolled glycemic level and 60% of them were in low socio-economic level. Children with diabetes had significantly lower HRQOL than healthy children in all domains. Age, glycemic control status and birth order of the diabetic children showed no significance difference regarding the QOL. Disease duration affected only the emotional function of the QOL and females showed significantly higher score regarding school functioning. Social, school and the total QOL scores were significantly higher among children with highly educated mothers while father's education affected the emotional, school and total QOL scores. Children in the middle and high social class showed significantly higher scores regarding social, school and total QOL. Presence of diabetic parent positively affected the social functioning while had negative effect on the school function of children with type I diabetes.Conclusions and recommendations: Diabetes is negatively affecting all the QOL functioning of the children. We recommend that Integrated programs between child's home, school and health insurance clinics for educating and supporting children with diabetes to improve their HRQOL.
Reviewer Acknowledgements for Review of European Studies, Vol. 9, No. 2
Authors: Dou Paige
Published: May 2017

Reviewer Acknowledgements for Review of European Studies, Vol. 9, No. 2, 2017
Generalized k–uniformly convex harmonic functions with negative coefficients
Authors: Li Shuhai , Tang Huo , Ma Lina , En Ao
Published: May 2017

In the present paper, we introduce some generalized $k$-uniformly convex harmonic functions with negative coefficients. Sufficient coefficient conditions, distortion bounds, extreme points, Hadamard product and partial sum for functions of these classes are obtained.
On inequalities of Hermite-Hadamard type for stochastic processes whose third derivative absolute values are quasi-convex
Authors: Materano Jesus Enrique , Merentes Nelson , Lopez-Valera Maira
Published: May 2017

In this paper we give some estimates of the right-hand side inequality of Hermite-Hadamad type for stochastic processes whose third derivatives in absolute values are quasi-convex.
Entire solution originating from three fronts for a discrete diffusive equation
Authors: Chen Yan Yu
Published: May 2017

In this paper, we study a discrete diffusive equation with a bistable nonlinearity. For this equation, there are three types of traveling fronts. By constructing some suitable pairs of super-sub-solutions, we show that there are only two types of entire solutions originating from three fronts of this equation. These results show us some new dynamics of this discrete diffusive equation.
Sentrum og snikksnakk. Luther i bruk - i samfunn og skole
Authors: Aas Per Anders
Published: May 2017

Approaching the 500-year Reformation anniversary, the article discusses what might legitimize Luther as a topic in today’s society and educational practice. Are his crucial ideas an exclusively religious heritage, or could they be converted to issues of common relevance? Referring to the ways Luther was used by the GDR state and church in the 1983 anniversary, the article questions the potential for recontextualizing his specifically theological issues. By this, it relates to a current debate in religion didactics whether stories could be taught according to their religiously specific or universal, existential dimensions – cf. the question of learning about or from religion. The cultural and political impact of Luther’s theology obviously makes it relevant as common heritage. His theological issue, however – man’s lack of free will (De servo arbitrio), and his view on «theological man» as defined solely by God’s justification (De homine), which Luther considers to be his primary concern – appears to be counter-intuitive, i.e. different from what seems right or natural. Hence, it challenges the concept of cultural heritage, but proves a critical corrective to common, essentialist justifications of human dignity, cultural identity and superiority – which makes it an issue to be learnt from and not only about.Emneord: Luther, reformasjonen, kulturarv, fagdidaktikk, religionsdidaktikk.
Luthers pedagogiske bidrag
Authors: Mogstad Sverre Dag
Published: May 2017

Er det noen god grunn for å trekke frem pedagogiske perspektiver i Luther- og reformasjonsjubileet? Martin Luther var verken pedagog eller politiker. Først og fremst var han teolog. Men hans teologiske tenkning fikk omfattende folkepedagogiske følger. I denne artikkelen skal jeg se på noen av disse, og spesielt hvordan hans teologi førte til et nytt syn på oppdragelsen, skolen og barnet. Til en viss grad vil jeg også trekke linjene fremover til vår egen tid. Men for å få tak i Luthers pedagogiske innflytelse, må vi først danne oss et bilde av samtidens pedagogiske arv og tenkning.Nøkkelord: Luther, , luthersk pedagogikk, skole, oppdragelse, barneteologi
Re:formation – teser, tro og tvivl - Et dansk undervisningsprojekt om reformationen i børnehøjde
Authors: Madsen Helle Krogh , Svensson Sidsel Leth
Published: May 2017

I 2017 er det jubilæumsår for reformationen. I den anledning udbyder Landsnetværket af Folkekirkelige Skoletjenester i Danmark et projekt til 5. og 6. klassetrin, hvor fokus både er på Martin Luther og hans tid og på følgerne af hans nye udlægning af kristendommen. Godt 30.000 danske skoleelever vil arbejde med reformationen i samarbejde med lokale folkekirker gennem projektet Re: formation – teser, tro og tvivl.Nøkkelord: reformasjonsjubileum, kirke-skolesamarbeid, undervisningsopplegg
Hans Hodne og Helje Kringlebotn Sødal: Å undervise om religion og livssyn på barnetrinnet
Authors: Flornes Kari
Published: May 2017

Anmeldelse av boka «Å undervise om religion og livssyn påbarnetrinnet» av Hans Hodne og Helje Kringlebotn Sødal. Anmeldt av Kari Flornes
Verdier i formålsparagraf og minnematerialet etter 22. juli 2011
Authors: Lied Sidsel , Stubø Ingebjørg
Published: May 2017

Many of the texts and drawings from spontaneous memorial places in the Oslo area in the days after the bombing of government buildings and  the shooting and killing of young people on Utøya island on July 22nd 2011, are made by children. The main focus of this article is what values these memorial utterances show that children considered important and worth fighting for in the aftermath of this event. Love and togetherness, life and human worth were often in focus in these utterances – utterances that are closely related to central values in the objects clause («formålsparagrafen») of the Norwegian Education Act, such as love for one’s neighbour, respect for human worth, diversity and solidarity. But children’s memorial utterances also indicate that the very fight for these values sometimes puts the same values under pressure: in some texts and drawings the terrorist is dehumanised and deprived of his human worth. The article gives examples of and discusses these phenomena. The theoretical perspective used in the article is Gunther Kress and Theo van Leeuwen’s grammar of western visual design.Nøkkelord: verdier, 22. juli, barns verdier, verdier i norsk skole, visuell meningsskaping
Grunnleggende ferdigheter i KRLE-læreverk
Authors: Hodne Hans
Published: May 2017

This article analyzes the relationship between basic skills and textbooks in the subject Christianity, religions, worldviews and ethics. Two research questions are discussed and answered: How can the basic skills be understood within the subject? And how do selected textbooks facilitate for working with the basic skills? The first question seeks to define and operationalize the basic skills within the context of the subject. This is done on the basis of official documents and current research, but also on an understanding of the subject which emphasizes both knowledge and formation. The answer to the first research question is used as an analytical resource for the discussion of the next question. The material being analyzed is three textbooks. With respect to knowledge, the article shows that textbooks manage to integrate the basic skills. However, the books could have paid more attention to some of the aspects of the skills which are specific for the subject. When it comes to aspects of formation and education the basic skills are mainly resources for ethical and philosophical topics, primarily to develop tolerance and respect within the pupils.Nøkkelord: lærebøker, religiøs utdanning i grunnskolen og videregående skole, grunnleggende ferdigheter, kunnskap, formasjon
Mellan verklighet och vision – en diskursanalys av Riktlinjer för Svenska kyrkans konfirmandarbete
Authors: Gustavsson Caroline
Published: May 2017

In the Lutheran Church of Sweden, Guidelines for the Confirmation Work serves as a framework for the confirmation process and presents the conditions within which Swedish church congregations can conduct high-quality confirmation work. The latest version of the document was presented in 2008; the previous version was released in 2000 and the version before that was published in the late 1990s. The present article aims to contribute to a perspective on the 2008 edition by exploring the discourses that are reflected in the document. The analysis reveals three dominant Orders of discourse: the target group, the context, and the content. The results raise the question of how guidelines can be expected to balance the expectations and visions from the national church, the dioceses, and the congregations.Nøkkelord: kirkelig konfirmasjon, retningslinjer, diskursanalyse, svensk kirke
Ei solid skattkiste eller skjøre leirkrukker? Om trosopplæring og religiøs identitet i en flerkulturell og flerreligiøs sammenheng
Authors: Schuerhoff Carsten
Published: May 2017

Religiøs identitet og læring «på tvers» – hvilke vilkår har det, midt i Groruddalen, i en drabantbymenighet? På noen trosopplæringstiltak er de færreste av deltakerne medlemmer av Den norske kirke, langt fra alle er kristne. Hvordan drive trosopplæring i et flerkulturelt og flerreligiøst lokalsamfunn? Hvilke implikasjoner gir seg til kjenne når en spør etter religiøs identitet i en slik setting? Hva er forholdet mellom misjon og dialog? Det er spørsmål denne artikkelen dreier seg om.
Et vanskelig samarbeid
Authors: Winje Geir
Published: May 2017

Et vanskelig samarbeid Av Geir Winje. Fungerer skole-kirkesamarbeid i tråd med retningslinjene for KRLE/RLE-faget? Debattinnlegg med kritikk av utvalgte trekk ved praksis og argumentasjon for eksisterende skole-kirkesamarbeid. Nøkkelord: skole-kirkesamarbeid, påskevandring
Religion og norskopplæring. Underkommunisering av religionen i norskopplæringa av voksne flerspråklige?
Authors: Engen Hans-Jacob
Published: May 2017

«Religion i fagkretsen er ikke relevant, fordi vi underviser i en religionsnøytral sone». Dette ble uttalt da jeg ble ansatt som norsklærer for voksne innvandrere. Religion er ikke et undervisningsfag for nyankomne innvandrere, og læreplanen inneholder bare faget norsk med samfunnskunnskap. Men for deltakerne er religion viktig. Jeg vil i denne artikkelen presentere en studie av religionens videre plass og dens betydning i undervisningen. Materialet peker mot at manglende kunnskap om religion og manglende tematisering av religion er til skade for læringsprosessen på flere måter, og motsatt: å tematisere religion og tilpasse undervisningen ut fra kjennskap til religion og religiøs praksis kan være en ressurs. I undersøkelsen min fant jeg eksempelvis et tilfelle der undervisningsopplegget ble dårlig fordi store deler av klassen var fraværende på grunn av en religiøs høytid læreren ikke hadde fått med seg. En kvinne som ellers knapt snakket norsk, pratet i mange minutter i sammenheng når hun snakket om noe hun var opptatt av – ramadan. Og et forbud mot bønn viser seg å kunne fungere mer forstyrrende enn som hjelp til konsentrasjon. Undersøkelsen viser at religion ser ut til å være en viktig didaktisk faktor på mange ulike måter selv i en erklært religionsløs skole.
Salmer i kirke og skole
Authors: Rong Marit
Published: May 2017

In the light of the Lutheran hymn tradition, the article investigates how the Plan for Christian Education of the Church of Norway reflects on hymn singing. The author compares hymn lists from a few congregations to the hymns in school songbooks. The article discuss the purpose and intention of hymn singing, and the correspondence between hymns used in church and the RLE subject. The core question is whether hymn singing is an expression of faith or of culture, and how hymn singing influences on identity.Keywords: Hymn singing in church • Christian education • Identification • Hymns in school songbooks • The curriculum of the RLE subjectNøkkelord: Salmesang i kirken • Kristendomsundervisning • Identifikasjon • Salmer i skolens sangbøker • Læreplanenen i RLE
«Engler og barnesanger» – og estetikk og religion
Authors: Trysnes Irene
Published: May 2017

Denne artikkelen tar for seg funn fra et forskningsprosjekt om religion og estetikk. Artikkelen ser på hvordan ulike religiøse miljøer nærmer seg hverandre og blir likere i uttrykksformer. I katolske og karismatiske ungdomsmiljøer synges de samme lovsangene. Lovsanger og kristne barnesanger legger vekt på positive elementer ved troen, tekstene forenkles og følger populærkulturelle trender. Miljøene preges av populærkulturelle uttrykk og opplevelser, og følelser tillegges stor vekt. Elementer fra ulike trosretninger trekkes også inn, og ny teknologi er med på å strømlinjeforme miljøene og gi dem et konsertpreget uttrykk.
Trenger vi flere lærebøker i religionsdidaktikk?
Authors: Von der Lippe Marie
Published: May 2017

Anmeldelse av boken:Kari Repstad og Inger Margrethe Tallaksen. Praktisk fagdidaktikk for religionsfagene.
En profesjonell, relasjonell aktør? Kateketen som leder i kvalitetsutvikling av lokal trosopplæring
Authors: Edvardsen Jo
Published: May 2017

Hvordan skal kirkens undervisningstjeneste organiseres? Hva innebærer kateketens rolle som leder av menighetens undervisning? Den pågående debatten reiser ikke bare spørsmål om stillingskategorier og strukturer, men også om forståelsen av å lede kirkelig undervisning. Med utgangspunkt i lokal trosopplæring reflekterer jeg rundt hvordan en mangfoldig kompetanse innenfor både pedagogikk og teologi er nødvendig for at kateketen kan utøve en profesjonell faglig ledelse. Ved å tilrettelegge for samhandling både med andre medarbeidere og med deltakere i trosopplæring kan de få bruke sine ressurser på en slik måte at ny kunnskap utvikles. I denne artikkelen vil jeg bruke mine erfaringer som kateket koplet mot et sosiokulturelt syn på læring og teorier om lærende organisasjoner.
Korskolen vår
Authors: Nese Kristin Vold
Published: May 2017

«Alle barn har en gnist i seg, det som gjelder er å tenne den.» Roald DahlKan det å synge gi oss livstolkning og livsmestring? Jeg mener det. Jeg har sunget helt fra jeg var ganske liten, nesten før jeg kunne snakke. Og sangen har gitt meg troens gave. Sangene har hjulpet meg gjennom livskriser. I trosopplæringen må vi tenke stort om sangene, de skal følge oss gjennom livet, i glede og sorg. Sangene besitter også den egenskapen at vi kan huske dikt og tekster, så kjernetekstene sitter best når vi synger dem.
Epistemic friction, affect and learning to know patients well: setting new norms for medical education
Authors: Potter Nancy Nyquist
Published: May 2017

Medical education takes seriously the centrality of treating the person and not just the illness. This paper engages with previous work on epistemic and ethical challenges to person-centered care. The aim of the paper is to identify some missing components that medical education must focus on if it wants to inculcate proper epistemic, ethical and affective skills in treating patients well. The argument has four parts: after introducing the problem and providing a background for this paper, I explain the relationship between objectivity and trust. In section II, I inquire into the conditions under which trust in physicians and in the medical establishment can be fostered. I explain the everyday realities of social situatedness that, I argue, must be taken into consideration in order to foster the right kind of objectivity and trust in medical fields. Section III builds on the previous sections by addressing problems of silencing that are systematic and harmful, especially to people from marginalized and minority groups. I draw on Kristie Dotson’s work of testimonial quieting and testimonial smothering in this section and apply it to patients in order to show how important it is to good doctoring practices that physicians learn to develop skills and virtues that address the epistemic problems this essay identifies. Section IV develops the main positive argument. Drawing upon Medina’s account of epistemic vices and virtues that are socially situated and systemically reproduced, I show what a thick notion of epistemic and ethical responsibility would look like. In particular, I argue that physicians need to know how to engage with, rather than remain detached from, epistemic friction in their encounters with patients and that such engagement requires affective sensibilities as well as epistemic and ethical ones. Coming full circle, I return to the starting point of the relationship between objectivity and trustworthiness and argue that struggles to develop a thick notion of physician responsibility in oneself simultaneously is epistemic, ethical, affective, social and political.
Developing an integrated educational simulation model by considering art approach: Teaching Empathic Communication skills
Authors: Yakhforoshha Afsaneh , Emami DR.Seyed Amir Hossein , Mohammadi Dr. Navid , Cheraghi Dr.Mohammadali , Mojtahedzadeh Rita , Mahmoodi-Bakhtiari Behrooz , Shirazi Mandana
Published: May 2017

Introduction: Simulation plays an important role in integrated learning of communication skills. Communication skills are known as the heart and art of medicine. Although, designing high-impact learning experiences in simulated environments are essential elements in the process of communication training, it has encountered some challenges. Art-based education by providing ‘simulation’ of the wider experience of life as well as making creative thinking in medical students can help to overcome these issues. This article aims to develop a new model of simulation for communication skills education, the Integrated Model for Communication Skills (IMCS), by integrating the essential features of simulation and art.Materials and Methods: A review was done on the current literature of medical education, simulation model and main framework of art approach. Then, an expert panel by the use of nominal group technique (NGT) was held with medical education experts in Iran and Sweden to design, select an appropriate simulation model and approve the final model (IMCS) following some modifications.Results: IMCS is an integrated model in 3 concepts of Jeffries simulation model based on art approaches: simulation design, simulation intervention and outcome. The model used activity theory and transformative learning theory to foster outcomes of skill-based and emotional-based communication skills.Conclusion: Arts strategies could be incorporated into the simulation model. The IMCS has the potential to promote emotional and technical aspects of communication skills to make the healthcare providers as competent communicators.
LEITURA DO MUNDO DE GESTANTES ADOLESCENTES: DESCOBRINDO UNIVERSO VOCABULAR BASEADO NO CÍRCULO DE CULTURA
Authors: Mendonça Glícia Mesquita Martiniano , Silva Maria Adelane Monteiro da , Abreu Leidy Dayane Paiva de , Viana Rebeca Sales , Rocha Francisca Alanny Araújo , Ferreira Junior Antonio Rodrigues
Published: May 2017

O artigo objetiva revelar o universo vocabular de leitura do mundo de gestantes adolescentes, baseado nos Círculos de Cultura de Paulo Freire. Trata-se de uma pesquisa exploratória de abordagem qualitativa realizada de outubro/2012 a maio/2013 com quatorze adolescentes. Para coleta das informações utilizou-se observação participante e diário de campo nos encontros grupais. A análise dos achados se deu mediante aplicação do método de Análise Temática de Minayo. A partir do diálogo, foi possível identificar palavras do universo vocabular das adolescentes, para então propiciar conscientização crítica e rica discussão quanto a amamentação, família e grupalidade. O estudo permitiu conhecer as palavras geradoras do universo vocabular de adolescentes grávidas: amamentação, apoio familiar, gravidez e história de vida. Destacaram-se palavras que possibilitam melhor atuação profissional no desenvolvimento de cuidados em saúde para gestantes adolescentes.Descritores: Gravidez na Adolescência; Educação em Saúde; Atenção Primária à Saúde.
PERFIL EPIDEMIOLÓGICO E SOCIAL DA FIBROSE CÍSTICA NA INFÂNCIA E ADOLESCÊNCIA
Authors: Santos Sueli Maria dos Reis , Barroso Mayara Dias , Duarte Thaís Rothier , Jesus Maria Cristina Pinto de
Published: May 2017

Objetivo: verificar o perfil epidemiológico e social da Fibrose Cística na infância e adolescência. Metodologia: estudo exploratório, descritivo, com abordagem qualitativa. Participaram 26 crianças e adolescentes com Fibrose Cística e seus responsáveis. Coletaram-se os dados utilizando um formulário e entrevista semiestruturada gravada em áudio. Para análise utilizou-se estatística descritiva e técnica de análise temática de conteúdo. Resultados: 34,6% idade entre 10 e 14 anos; 69,2% sexo masculino; 65,3% cor da pele branca; maioria morava em perímetro urbano; todos com idade superior a três anos frequentavam escola; 46,2% não tinham irmãos; 92,4% professavam alguma religião; 38,4% renda de um salário mínimo; 38,4% várias hospitalizações. Conclusão: doença precisa ser melhor divulgada. Para cuidar e conviver com a enfermidade a família apóia na espiritualidade para sustentar a esperança. A proporção de adultos com Fibrose Cística cresce progressivamente, gerando novas demandas para os serviços de saúde.Descritores: Fibrose Cística; Infância; Adolescência; Enfermagem.
AVALIAÇÃO DA QUALIDADE DE VIDA DE PACIENTES SUBMETIDOS AO TRANSPLANTE DE CÉLULAS-TRONCO HEMATOPOÉTICAS
Authors: Santos Marciele Braga dos , Cardoso Andreza Lima , Schio Bruna , Leal Francine Ziegler , Mielke Jenifer Colombelli , Mozzaquatro Juliana De Oliveira , Horner Rosmari
Published: May 2017

O objetivo do presente trabalho foi avaliar a qualidade de vida (QV) dos pacientes pós transplante de células tronco hematopoéticas (TCTH) autólogo e alogênico. Trata-se de um estudo descritivo, exploratório com abordagem quali-quantitativa, realizado nos meses de março a dezembro de 2016 - em um Hospital Universitário. Fizeram parte da pesquisa 21 pacientes adultos pós-TCTH, que seguiam acompanhamento no referido hospital, sendo utilizada a escala de avaliação funcional da terapia do câncer – transplante de medula óssea (Functional Assessment of Cancer Therapy - Bone Marrow Transplantation - FACT-BMT) e para análise dos dados, o programa Statistical Package for Social Sciences (SPSS), versão 15.0. Os resultados obtidos neste estudo permitem ratificar, comparando com avaliações nacionais e internacionais, o impacto positivo do TCTH em relação à qualidade de vida geral dos pacientes submetidos a este tratamento, apesar de algumas funções apresentarem-se mais comprometidas. Estudos que identificam a influência dos efeitos do TCTH na QV dos pacientes submetidos a esse procedimento são escassos. Conhecer o impacto do TCTH na vida do transplantado auxilia a equipe multidisciplinar a desenvolver um plano de assistência integral com estratégias para diminuir os efeitos colaterais desse procedimento e melhorar a qualidade de vida do paciente em todos os momentos do tratamento.Descritores: Transplante de Medula Óssea; Qualidade de Vida; Internato não Médico.
Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loops
Authors: Liu Jie , Ede Christopher , Wright William D , Gore Steven K , Jenkins Shirin S , Freudenthal Bret D , Todd Washington M , Veaute Xavier , Heyer Wolf-Dietrich
Published: May 2017

Synthesis-dependent strand annealing (SDSA) is the preferred mode of homologous recombination in somatic cells leading to an obligatory non-crossover outcome, thus avoiding the potential for chromosomal rearrangements and loss of heterozygosity. Genetic analysis identified the Srs2 helicase as a prime candidate to promote SDSA. Here, we demonstrate that Srs2 disrupts D-loops in an ATP-dependent fashion and with a distinct polarity. Specifically, we partly reconstitute the SDSA pathway using Rad51, Rad54, RPA, RFC, DNA Polymerase δ with different forms of PCNA. Consistent with genetic data showing the requirement for SUMO and PCNA binding for the SDSA role of Srs2, Srs2 displays a slight but significant preference to disrupt extending D-loops over unextended D-loops when SUMOylated PCNA is present, compared to unmodified PCNA or monoubiquitinated PCNA. Our data establish a biochemical mechanism for the role of Srs2 in crossover suppression by promoting SDSA through disruption of extended D-loops.
mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
Authors: Burke Luke K , Darwish Tamana , Cavanaugh Althea R , Virtue Sam , Roth Emma , Morro Joanna , Liu Shun-Mei , Xia Jing , Dalley Jeffrey W , Burling Keith , Chua Streamson , Vidal-Puig Toni , Schwartz Gary J , Blouet Clémence
Published: May 2017

Energy dissipation through interscapular brown adipose tissue (iBAT) thermogenesis is an important contributor to adaptive energy expenditure. However, it remains unresolved how acute and chronic changes in energy availability are detected by the brain to adjust iBAT activity and maintain energy homeostasis. Here, we provide evidence that AGRP inhibitory tone to iBAT represents an energy-sparing circuit that integrates environmental food cues and internal signals of energy availability. We establish a role for the nutrient-sensing mTORC1 signaling pathway within AGRP neurons in the detection of environmental food cues and internal signals of energy availability, and in the bi-directional control of iBAT thermogenesis during nutrient deficiency and excess. Collectively, our findings provide insights into how mTORC1 signaling within AGRP neurons surveys energy availability to engage iBAT thermogenesis, and identify AGRP neurons as a neuronal substrate for the coordination of energy intake and adaptive expenditure under varying physiological and environmental contexts.
Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt)
Authors: Erickson Timothy , Morgan Clive P , Olt Jennifer , Hardy Katherine , Busch-Nentwich Elisabeth , Maeda Reo , Clemens Rachel , Krey Jocelyn F , Nechiporuk Alex , Barr-Gillespie Peter G , Marcotti Walter , Nicolson Teresa
Published: May 2017

Transmembrane O-methyltransferase (TOMT/LRTOMT) is responsible for non-syndromic deafness DFNB63. However, the specific defects that lead to hearing loss have not been described. Using a zebrafish model of DFNB63, we show that the auditory and vestibular phenotypes are due to a lack of mechanotransduction (MET) in Tomt-deficient hair cells. GFP-tagged Tomt is enriched in the Golgi of hair cells, suggesting that Tomt might regulate the trafficking of other MET components to the hair bundle. We found that Tmc1/2 proteins are specifically excluded from the hair bundle in tomt mutants, whereas other MET complex proteins can still localize to the bundle. Furthermore, mouse TOMT and TMC1 can directly interact in HEK 293 cells, and this interaction is modulated by His183 in TOMT. Thus, we propose a model of MET complex assembly where Tomt and the Tmcs interact within the secretory pathway to traffic Tmc proteins to the hair bundle.
Cell descent caused by boundary curvature of a high topographical
structure for a device that changes cell density
Authors: Okutani Chihiro , Wagatsuma Akira , Mabuchi Kunihiko , Hoshino Takayuki
Published: May 2017

Noninvasive techniques of controlling cell migration on substrates are widely
useful for tissue engineering. However, the cell migration controls of previous
studies were not enough for collecting cells locally. To solve this problem, in
this work, we report the C2C12 mouse myoblast cell migration difference (descend
or be repelled) by changing the curvature of the boundary of a topographical
structure when the cells move from a flat surface to the boundary. 69% of the
cells coming across a round boundary — the curvature radius of which was
50 µm — descended into the hole. In contrast, no cells descended
into a groove with a linear boundary. Moreover, we demonstrated the cell spatial
density change from the difference at the boundary. This finding will provide a
new device that will enable us to manipulate spatial cell density noninvasively
for tissue engineering.
Output-Based Instruction, Learning Styles and Vocabulary Learning in the EFL Context of Iran
Authors: Rastegar Behnaz , Safari Fatemeh
Published: May 2017

Language learners' productive role in teaching and learning processes has recently been the focus of attention. Therefore, this study aimed at investigating the effect of oral vs. written output-based instruction on English as a foreign language (EFL) learners' vocabulary learning with a focus on reflective vs. impulsive learning styles. To this end, 131 learners were chosen among 182 learners by taking Nelson vocabulary proficiency test. Next, the participants received a valid Persian version of reflective thinking (Kember et al., 2000) and Barratt, Patton and Stanford (1975) BIS (Barratt’s Impulsiveness Scale) 11 impulsiveness questionnaires, based on which both experimental groups were divided into impulsive and reflective subgroups, but the control group consisted of both impulsive and reflective learners. After 15 sessions of intervention and based on the results through one-way ANOVA and independent t-test it was concluded that both oral output and written output had significant effect on vocabulary learning of reflective and impulsive EFL Learners. It was also observed that the effect of both oral output and written output on impulsive (oral group’s mean=21.04; written groups’ mean= 21.75) learners and reflective learners (oral groups’ mean=22.38; written group’s mean: 22.23) is not significantly different. Pedagogical implications are discussed.
The Relationship between Cultural Identity, Intrinsic Motivation and Pronunciation Knowledge of Iranian EFL Learners
Authors: Shabani Somayyeh , Alipoor Iman
Published: May 2017

Gardener’s (1985) socio-cultural model shows that culture is among the variables that can affect learning languages. In addition, a series of studies were prompted by Dörnyie (2005) to gauge the effect of motivation on language learning. This correlational study endeavored to find out any possible interaction between these variables, i.e., cultural identity, intrinsic motivation, and pronunciation knowledge of Iranian EFL learners at intermediate level. To this end, 9 items from Mathews’ Cultural Identity Questionnaire (2007) (as cited in Bazrafshan, 2015) along with intrinsic/extrinsic motivation questionnaire developed by Noels, Pelletier, Clement, and Vallerand (2000) were given to the 49 intermediate Iranian EFL learners who were selected among 74 learners studying at Mahan Language Institute in Birjand. The participants’ pronunciation knowledge was also measured through an interview. The results of the data analysis through Pearson correlation revealed that cultural identity shows no relationship with pronunciation knowledge of the participants, whereas more intrinsically motivated language learners gained higher scores on the pronunciation test. Pedagogical implications are discussed.
Elevskap mot frafall i videregående skole
Authors: Thunberg Odd Arne , Andreassen Svein-Erik
Published: May 2017

Artikkelen retter fokus mot frafallsproblematikk i videregående skole. En mulig løsning er å øke elevenes kompetanse i å gjøre karrierevalg. I en videreutdanningsstudie i yrkesveiledning har skolerådgivere og lærere arbeidet med å utvikle mulige løsninger gjennom FoU-arbeid på egne arbeidsplasser.Data er samlet inn fra bl.a. veiledningssamtaler og eksamensoppgaver. Som analyseredskaper er teoretiske begreper fra Ellstrøm (2006) anvendt; tilpasningslæring og idealet elevskap i utviklingslæring.Artikkelens funn er at medbestemmelse – ikke bare medvirkning – i valg av aktiviteter, rådgiver, utdanning og skolested øker elevens kompetanse i å gjøre karrierevalg.Artikkelen bidrar med praktiske eksempler på hvordan skolene kan lykkes med dette, med utgangspunkt i faget Utdanningsvalg. Faget ble obligatorisk på ungdomsskoletrinnet fra 2008.
The first reported ceratopsid dinosaur from eastern North America (Owl Creek Formation, Upper Cretaceous, Mississippi, USA)
Authors: Farke Andrew A. , Phillips George E.
Published: May 2017

Ceratopsids (“horned dinosaurs”) are known from western North America and Asia, a distribution reflecting an inferred subaerial link between the two landmasses during the Late Cretaceous. However, this clade was previously unknown from eastern North America, presumably due to limited outcrop of the appropriate age and depositional environment as well as the separation of eastern and western North America by the Western Interior Seaway during much of the Late Cretaceous. A dentary tooth from the Owl Creek Formation (late Maastrichtian) of Union County, Mississippi, represents the first reported occurrence of Ceratopsidae from eastern North America. This tooth shows a combination of features typical of Ceratopsidae, including a double root and a prominent, blade-like carina. Based on the age of the fossil, we hypothesize that it is consistent with a dispersal of ceratopsids into eastern North America during the very latest Cretaceous, presumably after the two halves of North America were reunited following the retreat of the Western Interior Seaway.
Within outlying mean indexes: refining the OMI analysis for the realized niche decomposition
Authors: Karasiewicz Stéphane , Dolédec Sylvain , Lefebvre Sébastien
Published: May 2017

The ecological niche concept has regained interest under environmental change (e.g., climate change, eutrophication, and habitat destruction), especially to study the impacts on niche shift and conservatism. Here, we propose the within outlying mean indexes (WitOMI), which refine the outlying mean index (OMI) analysis by using its properties in combination with theK-select analysis species marginality decomposition. The purpose is to decompose the ecological niche into subniches associated with the experimental design, i.e., taking into account temporal and/or spatial subsets. WitOMI emphasize the habitat conditions that contribute (1) to the definition of species’ niches using all available conditions and, at the same time, (2) to the delineation of species’ subniches according to given subsets of dates or sites. The latter aspect allows addressing niche dynamics by highlighting the influence of atypical habitat conditions on species at a given time and/or space. Then, (3) the biological constraint exerted on the species subniche becomes observable within Euclidean space as the difference between the existing fundamental subniche and the realized subniche. We illustrate the decomposition of published OMI analyses, using spatial and temporal examples. The species assemblage’s subniches are comparable to the same environmental gradient, producing a more accurate and precise description of the assemblage niche distribution under environmental change. The WitOMI calculations are available in the open-access R package “subniche.”
Обнаружение вынужденного комбинационного рассеяния в кристалле LiYbF4, "Доклады Академии наук"
Authors: Каминский А. А.
Published: May 2017

Сообщается об обнаружении вынужденного комбинационного рассеяния (ВКР) в тетрагональном кристалле LiYbF4. Зарегистрированные компоненты стоксовой и антистоксовой (3)-нелинейной генерации идентифицированы с его двумя ВКР-активными фононными модами wВКР1 ~ 325 см-1 и wВКР2 ~ 432 см-1.
Influence of the Canton Tower on the cloud‐to‐ground lightning in its vicinity
Authors: Zhang Changxiu , Lu Weitao , Chen Luwen , Qi Qi , Ma Ying , Yao Wen , Zhang Yijun
Published: May 2017

This paper analyzed the influence of the Canton Tower on cloud‐to‐ground lightning in its vicinity based on the data obtained by Lightning Location System (LLS) of the Guangdong Power Grid Corporation from 1999 to 2015. The LLS data obtained before (1999–2005) and after (2010–2015) the erection of the Canton Tower were compared. The flash/stroke density showed a significant increase in the immediate vicinity around the Canton Tower within a radius of 1 km and a clear decrease in the annular vicinity with a radius from 1 km to 4 km. The arithmetic mean and median LLS‐inferred peak current of strokes that occurred in 1 km radius area around the Canton Tower exhibited a significant increase, while that of the strokes that occurred beyond 1 km did not show a clear change. The percentage of negative flashes (ratio of negative flashes to total flashes) showed a slight increase in the immediate vicinity around the Canton Tower, which could be caused by the upward lightning (often negative) initiated from the tower. Due to the existence of the Canton Tower, the lightning multiplicity presented a decreasing trend to some extent within 4 km radius around the tower compared with the arithmetic mean value within 10 km radius. It is speculated that the Canton Tower induced lots of upward flashes and attracted some downward flashes around it within several kilometers radius to itself.
On the upward flux of sea‐spray spume droplets in high‐wind conditions
Authors: Wu Lin , Cheng Xueling , Zeng Qingcun , Jin Jiangbo , Huang Jian , Feng Yerong
Published: May 2017

It has been speculated that the spume droplets torn off from ocean waves in high wind speeds (larger than about 9 m s−1) enhance air‐sea fluxes. However, the vertical transport of spume droplets in the high‐wind atmospheric boundary layer (ABL) is little researched and lacks the support of numerical simulations. Based on observational data and the characteristics of high‐wind ABL above the ocean, the vertical transport of spume droplets is studied and simulated. It is revealed that the existence of gusty wind with coherent structure during high winds is favorable for the vertical transport of the large‐size droplets. The trajectories of 1000 spume droplets with different sizes under different wind speeds in the range 10–35 m s−1 are calculated, and the uplifting fraction of spume droplets that can reach the 100 m height in the ABL is parameterized by using a nondimensional factor U102/(r80g), where U10 is the wind speed at 10 m height, r80 the equilibrium radius of droplet at an equivalent 80% relative humidity, and g the gravitational acceleration. Then, the upward flux of large‐size spume droplets and the mass concentration at 100 m height are evaluated. These numerical results are comparable to some observational data and show that the large‐size spume droplets can be entrained into the ABL during high winds and then contribute to the air‐sea mass fluxes.
Geochemistry and microbial community composition across a range of acid mine drainage impact and implications for the Neoarchean‐Paleoproterozoic transition
Authors: Havig Jeff R. , Grettenberger Christen , Hamilton Trinity L.
Published: May 2017

Streams impacted by acid mine drainage (AMD, also known as acid rock drainage) represent local environmental and ecological disasters; however, they may also present an opportunity to study microbial communities in environments analogous to past conditions. Neoarchean continents had streams and rivers replete with detrital pyrites. Following the emergence of oxygenic photosynthesis, Cyanobacteria colonized streams and rivers on continental surfaces. The combination of labile detrital pyrite grains and locally produced O2 generated by Cyanobacteria produced ideal conditions for pyrite oxidation similar to that found at modern AMD‐impacted sites. To explore the connection of modern sites to ancient conditions, we sampled sites that exhibited a range of AMD‐impact (e.g., pH from 2.1 to 7.9 [Fe2+] up to 5.2 mmol/L [SO42−] from 0.3 to 52.4 mmol/L) and found (i) nearly all analytes correlated to sulfate concentration; (ii) all sites exhibited the predominance of a single taxon most closely related to Ferrovum myxofaciens, an Fe‐oxidixing betaproteoabacterium capable of carbon and nitrogen fixation, and (iii) signs of potential inorganic carbon limitation and nitrogen cycling. From these findings and building on the work of others, we present a conceptual model of continental surfaces during the Neoarchean and Paleoproterozoic linking local O2 production to pyrite oxidation on continental surfaces to sulfate production and delivery to nearshore environments. The delivery of sulfate drives sulfate reduction and euxinia—favoring anoxygenic photosynthesis over cyanobacterial O2 generation in near‐continent/shelf marine environments.
Habitat and spatial thinning improve the Maxent models performed with incomplete data
Authors: Kiedrzyński Marcin , Zielińska Katarzyna M. , Rewicz Agnieszka , Kiedrzyńska Edyta
Published: May 2017

Species distribution models need adequate sets of data, particularly in the case of range‐restricted species. The problem faced in the modeling of rare species is twofold: a small sample size and the occurrence of sampling biases. The present analysis combines spatial‐ and habitat‐thinning approaches to improve maximum entropy models based on geographically incomplete data of relict and subendemic Festuca amethystina L. grass on Polish territory. The results show that models based on strongly incomplete historic data did not predict the occurrence of all important areas where the species was found in the following decades. However, the introduction of species‐specific thinning allows for more precise prediction of the species range, i.e., the detection of suitable areas on a more local scale. The introduction of habitat thinning caused the diversity of important predictors in model to increase, but spatial thinning decreased the number of significant predictors and made interpretation easier. Additionally, a combination of thinning techniques allowed significant improvements to be made to the model predictions after the experimental addition of a lower number of localities to regions which had previously been poorly recognized. It can be concluded that in the case of incomplete data, the above corrections allow the true range of the species to be predicted after the discovery of a lower number and relatively dispersed new localities.
Investigating molecular changes in organic matter composition in two Holocene lake‐sediment records from central Sweden using pyrolysis‐GC/MS
Authors: Ninnes Sofia , Tolu Julie , Meyer‐Jacob Carsten , Mighall Tim M. , Bindler Richard
Published: May 2017

Organic matter (OM) is a key component of lake sediments, affecting carbon, nutrient, and trace metal cycling at local and global scales. Yet little is known about long‐term (millennial) changes in OM composition due to the inherent chemical complexity arising from multiple OM sources and from secondary transformations. In this study we explore how the molecular composition of OM changes throughout the Holocene in two adjacent boreal lakes in central Sweden and compare molecular‐level information with conventional OM variables, including total carbon, total nitrogen, C:N ratios, δ13C, and δ15N. To characterize the molecular OM composition, we employed a new method based on pyrolysis‐gas chromatography/mass spectrometry (Py‐GC/MS), which yields semiquantitative data on >100 organic compounds of different origin and degradation status. We identify large changes in OM composition after deglaciation (circa 8500 ± 500 B.C.), associated with early landscape development, and during the most recent 40–50 years, driven by degradation processes. With molecular‐level information we can also distinguish between natural landscape development and human catchment disturbance during the last 1700 years. Our study demonstrates that characterization of the molecular OM composition by the high‐throughput Py‐GC/MS method is an efficient complement to conventional OM variables for identification and understanding of past OM dynamics in lake‐sediment records. Holocene changes observed for pyrolytic compounds and compound classes known for having different reactivity indicate the need for further paleo‐reconstruction of the molecular OM composition to better understand both past and future OM dynamics and associated environmental changes.