bluuebunny/crossref_metadata_2025 huggingface dataset:
Farmaci antitumorali e tromboembolismo venoso
Authors: Pancani Roberta , Pagano Alessandra , Lomi Marta , Casto Elisabetta , Cappelli Sara , Celi Alessandro
Published: September 2023

Studi di popolazione hanno evidenziato un incremento dell’incidenza di tromboembolismo venoso (TEV) nei pazienti neoplastici in corso di trattamento con farmaci antitumorali. Sono state condotte ricerche cliniche allo scopo di chiarire il possibile ruolo di singoli agenti antitumorali nella modulazione del rischio di TEV, riscontrando fra essi alcune differenze. Gli studi disponibili presentano diversi limiti: non consentono un confronto diretto tra molecole poiché gli schemi di trattamento si basano generalmente su combinazioni di farmaci e spesso per ricavare dati su una singola molecola è necessario estendere lo studio a tumori di tipologie, sedi o comportamento biologico differenti; inoltre è probabile che alle differenze riscontrate contribuisca un rischio di TEV già di per sé aumentato nei pazienti in fase avanzata di malattia. Una possibile strategia per limitare l’incidenza di TEV potrebbe essere quella di sottoporre i pazienti oncologici in trattamento antitumorale a profilassi antitrombotica primaria. Per tale profilassi non esiste attualmente una raccomandazione solida, in virtù di dati contrastanti, sia sulle terapie con eparine frazionate che con farmaci anticoagulanti orali diretti (DOAC), sul rapporto fra il beneficio in termini di prevenzione degli eventi tromboembolici sintomatici ed il rischio di sanguinamenti maggiori o clinicamente rilevanti. L’introduzione in commercio di inibitori del fattore XIa, dei quali sono in corso studi di fase 2, potrebbe modificare lo scenario attuale. Un problema che sta acquisendo rilevanza sempre maggiore è quello delle possibili interazioni farmacologiche fra i farmaci anticoagulanti orali e i farmaci antitumorali. In questo senso, l’utilizzo dei DOAC può essere vantaggioso rispetto a quello degli inibitori della vitamina K, nonostante una potenziale maggiore difficoltà nel controllo delle interazioni, qualora presenti, dovuta al fatto che il dosaggio plasmatico dei DOAC non viene normalmente sottoposta a monitoraggio. Le interazioni fra i DOAC e i farmaci antitumorali sono state ipotizzate sulla base dell’azione su molecole coinvolte nella farmacodinamica di entrambe le categorie di farmaci, quali la glicoproteina-p (P-gp) o il citocromo CYP3A4; pur non essendo mai state studiate in vivo, è necessario prendere in considerazione la possibilità di tali interazioni nella pratica clinica. Alcune opportunità per affrontare il problema sono rappresentate dal dosaggio plasmatico dei DOAC e dalla somministrazione dei due farmaci in momenti il più possibile lontani nella giornata.
Fibrillazione atriale e neoplasie: scelta dell’anticoagulante
Authors: Capozza Paola Francesca , De Caterina Raffaele
Published: September 2023

La fibrillazione atriale rappresenta l’aritmia sostenuta più frequente nella popolazione generale e la sua incidenza è in costante aumento. D’altro canto, sebbene grazie alle politiche di screening e all’avanzamento delle terapie, la sopravvivenza nella popolazione affetta da neoplasie sia sensibilmente aumentata, rimane il fatto che i pz affetti da cancro in fase attiva hanno un rischio molto maggiore, rispetto alla popolazione generale, di sviluppare la fibrillazione atriale. Questo pone il medico cardiologo ed il medico oncologo di fronte alla necessità di intraprendere una terapia anticoagulante efficace e sicura per il paziente. I farmaci anticoagulanti diretti rappresentano sicuramente la prima scelta terapeutica, anche se è necessaria una valutazione accurata delle terapie concomitanti del paziente, un attento monitoraggio clinico ed un approccio dinamico all’evoluzione della storia clinica del singolo paziente.
Education Between Foreseeing The Future and Requesting Quality and Accreditation
Authors: Al-Momani Mohammad Omar
Published: September 2023

The study aimed to identify the current education system between looking forward to the future and asking for quality and reliability, as the issue of quality and accreditation occupied many educators and specialists in this field from the principle of providing a high degree of reliability for all educational and educational programs and the youth represented in the teacher, the curriculum and the educational environment, whether in the school stage University mother, in addition to the importance of the presence of modern technology in education and its impact on future generations in the future; Where this study came to shed light on the importance of education and its impact on individuals and societies through the introduction of all kinds of educational and technological innovations; The study followed the qualitative analytical approach, which is based on the theoretical research study. This study concluded that it is necessary to work on strengthening education, whether it is school or university, with all that is new in terms of knowledge and modern technologies, whose impact is reflected on students and society as a whole and contributes to the continuity of progress, growth and prosperity of societies
PEMBELAJARAN OLAH RAGA DENGAN MODEL KONTEKSTUAL UNTUK MENINGKATKAN KEMAMPUAN GERAK DASAR
Authors: Komaludin Dudi
Published: September 2023

Salah satu tugas perkembangan anak adalah mengembangkan gerak dasar anak sesuai dengan usianya. Tujuan pendidikan jasmani yaitu mengembangkan kemampuan koordinasi gerak, menanamkan nilai-nilai sportivitas, disiplin, dan meningkatkan kesegaran jasmani. Untuk mencapai tujuan yang diharapkan pada pembelajaran keterampilan gerak diperlukan model pembelajaran yang menyenangkan sesuai dengan karakteristik anak. Salah satu model tersebut yaitu model pembelajaran kontekstual. Pembelajaran kontekstual adalah suatu pendekatan pembelajaran yang menekankan kepada proses keterlibatan siswa secara penuh untuk dapat menemukan materi yang dipelajari dan menghubungkanya dengan situasi kehidupan nyata sehingga mendorong siswa untuk dapat menerapkannya dalam kehidupan yang nyata. Penelitian ini mengunakan pendekatan kuantitatif dengan metode penelitian kuasi eksperimen pada siswa SD Padasuka 1 dan 2. Berdasarkan pedoman interpretasi Guildford, koefisien korelasi tersebut termasuk pada kategori hubungan yang sedang. Adapun t hitung (5,70) t tabel (2,013). Jadi, pendidikan olah raga dengan model kontekstual memiliki hubungan erat terhadap peningkatan kemampuan gerak dasar. One of the tasks of child development is to develop children's basic movements according to their age. The purpose of physical education is to develop the ability to coordinate movement, instill the values of sportsmanship, discipline, and improve physical fitness. To achieve the expected goals in the learning of motion skills a fun learning model is needed in accordance with the characteristics of the child. One such model is the contextual learning model. Contextual learning is a learning approach that emphasizes the process of full student involvement to be able to find the material being studied and relate it to real life situations so as to encourage students to be able to apply it in real life. This study uses a quantitative approach with a quasi-experimental research method in Padasuka 1 and 2 elementary students. Based on the Guildford interpretation guidelines, the correlation coefficient is included in the moderate relationship category. The t count (5.70) t table (2.013). So, sports education with a contextual model has a close relationship with increasing basic mobility
HUBUNGAN DISIPLIN DAN MOTIVASI KERJA DENGAN KINERJA GURU DALAM MENGAJAR IPS DI MADRASAH IBTIDAIYAH KABUPATEN GARUT
Authors: Nurjamaludin Muhammad
Published: September 2023

The purposes of this study was to know whether there is a positive influence between working motivation towards teachers’ performance of social study in the Madrasah Ibtidaiyah in Karangpawitan District, Garut. The method used in this research is descriptive quantitative method with a number of samples of 120 teachers. The instruments are compiled in these study as many as 60 items of three variables. From the results of research show that F count of 25.091, since F count (25.091) F table 3.07, then Ho is rejected. It can be concluded that there is simultaneously a significant influence on working discipline and working motivation on the teachers’ performance in teaching social study. The magnitude of the effect of variable discipline and motivation influence 30% of the teaching performance of teachers while the remaining 70% is contributed by other variables not examined in this study.
PENDIDIKAN SENI TARI SEBAGAIPendidikan Seni Tari sebagai Alternatif Pendidikan Multikultur bagi Siswa SD ALTERNATIF PENDIDIKAN MULTIKULTUR BAGI SISWA SD
Authors: Cahya Anasta Non Dwishiera
Published: September 2023

Dance art is a work of art that contains a cultural encyclopedia. Traditional dance in Indonesia is a representation of multicultural Indonesian society, because traditional dance represents philosophical messages, both in the spiritual, moral and social aspects of the supporting community. This article examines how dance education has benefits for multicultural education for elementary school children. The aim is to explain the meaning of cultural diversity as something that is beneficial for the lives of local, national and global communities. Through dance education in elementary schools, students can be creative and appreciate the art of Indonesian dance. So it is expected that elementary students will know the treasures of their own nation's dance, as well as learn about the cultural differences between regions. Thus, they will become individuals who are able to respect differences and diversity, and accept the reality of the plurality of cultures that exist in Indonesia
PERIS ALBENTOSA, Tomàs, 2019, Enciclopèdia del regadiu històric valencià. Infraestructures hidràuliques i distribució de l’aigua.
Authors: Calatayud Giner Salvador
Published: September 2023

PERIS ALBENTOSA, Tomàs, 2019, Enciclopèdia del regadiu històric valencià. Infraestructures hidràuliques i distribució de l’aigua. Valencia, Generalitat Valenciana, Universitat de València, Academia Valenciana de la Llengua, Cátedra Demetrio Ribes y Acequia Real del Júcar, 774 págs. ISBN 978-84-482-6421-5.
Right to Repatriation of Abandoned Seafarers: A Study in Light of Maritime Labour Convention 2006, and International Covenant on Civil and Political Rights 1966
Authors: Gupta Mohit
Published: September 2023

The abandonment of seafarers is one of the major challenges that seafarers onboard vessels may face. In 2022, 1555 seafarers were abandoned on 113 ships. The port state's role in seafarer abandonment is crucial because it can assist abandoned seafarers by facilitating their repatriation. In practice, however, it has been seen in many cases that the port state of the vessel had restricted the disembarkation of the abandoned crew from the vessel by citing the reason that the vessel cannot be left unmanned. The present study will assess such measures adopted by the port states in light of International Law instruments, including the Maritime Labour Convention, 2006 and the International Covenant on Civil and Political Rights, 1966.
As we live, so we believe, so we worship together
Authors: Scott Hilton
Published: September 2023

The adage lex orandi, lex credendi, lex vivendi (or lex (con)vivendi) denotes causal interrelationships between worship, belief and life. Simply one affects the others as this adage forms the foundation of doctrine and/or a moral life. However, if there are true causal relationships between “as we worship” (lex orandi), “so we believe” (lex credendi), “so we live” (lex vivendi) then the adage can also be understood as: “as we live” (lex vivendi), “so we believe” (lex credendi), “so we worship” (lex orandi). This leads o the question: how does popular art and music in the lived experience (lex vivendi) influence/affect belief and therefore worship? In terms of promoting acceptance in the church this investigation begins by using two examples from popular music by Taylor Swift and two examples from British rapper Stormzy with the supposition that the artists intend to provoke a change in thinking that encourages an ethical acceptance of difference across society. This article is from a paper that was presented at the 2021 Societas Liturgica Conference hosted by University of Notre Dame.
MARMARA BÖLGESİNDEKİ TÜKETİCİLERİN HAYVANSAL KÖKENLİ GIDA TÜKETİM TERCİHLERİNİN BELİRLENMESİ VE TÜKETİCİYE BAĞLI DEĞİŞKENLERİN MİKROBİYOLOJİK AÇIDAN DEĞERLENDİRİLMESİ
Authors: SEZGİN Funda H. , DÜMEN Emek , BAYRAKAL Gülay Merve
Published: September 2023

Gıdalar üretim transport ve satış aşamalarında en doğru prosedürler uygulanarak üretilse bile, satın alınan gıdalar, tüketicinin evine girdikten birçok farklı değişkene bağlı olarak insan sağlığı açısından çok önenmli risk faktörleri haline dönüşebililir. Bu çalışmanın amacı, Marmara bölgesi kapsamında, Edirne, Tekirdağ, Kırlareli, İstanbul, Kocaeli, Adapazarı, Yalova, Bursa, Bilecik, Balıkesir, Çanakkale illeri için, hayvansal kökenli gıda ürünleri (süt ve ürünleri, et ve ürünleri, su ürünleri, kanatlı et ve ürünleri olmak üzere) hanehalkı tüketim profillerini belirlemek ve bu ürünlerinin mikrobiyolojik açıdan durumunu değerlendirmektir. Veriler normal dağılımlı olmadığı için parametrik olmayan yöntemlerden Kruskal-Wallis testi uygulanmıştır. Analiz sonucunda, mikrobiyolojik parametreler açısından, et ve et ürünleri ile süt ve süt ürünleri için anlamlı farklılık belirlenmiştir (p<0.05). Buna karşılık, su ürünleri ve kanatlı et- et ürünleri için anlamlı farklılık elde edilmemiştir (p>0.05). Farkın kaynağına bakıldığında, hem et ve et ürünleri için hem de süt ve süt ürünleri için E. Coli ve Koliform Grubu anlamlı şekilde yüksek olarak elde edilmiştir.
TÜRKİYE’DE TÜKETİCİ KREDİLERİNİN BELİRLEYİCİLERİ: ALTERNATİF TÜKETİCİ KREDİLERİ ÜZERİNE BİR İNCELEME
Authors: Tunay K. Batu , Tunay Necla
Published: September 2023

Risklilikleri kurumsal kredilere oranla düşük ve karlılıkları tatminkâr oranda yüksek olduğundan tüketici kredileri bankalar için önemli bir plasman türüdür. Hane halkının da çeşitli tüketim harcamalarının finansmanı için bu kredilere yönelik ciddi bir talebi olduğu görülmektedir. Bu tespitler Türkiye içinde önemli oranda geçerlidir ve son yıllarda tüketici kredilerinin hacmi giderek artmıştır. Çalışmamızda uluslararası literatür ışığında Türkiye’de tüketici kredilerinin belirleyicileri ekonometrik olarak araştırılmıştır. Dinamik yapıdaki iki regresyon modeli kullanılarak, 2005:4 ile 2022:4 dönemlerini kapsayan ve üç aylık verilerden oluşan bir örneklem analiz edilmiştir. Yapılan analizlerde alternatif tüketici kredilerini açıklayan değişkenler belirlenmeye çalışılmıştır. Elde edilen bulgular, tüketici kredilerinin geçmişe bağlılık gösterdiğini ve hemen tüm tahminlerde harcanabilir gelir düzeyinden pozitif ve faiz oranından negatif etkilendiğini ortaya koymuştur. Bazı modellerde, enflasyon ve işsizlik oranlarının da tüketici kredileri üzerinde etkili olduğu görülmüştür. Tüketici kredileri, enflasyon oranından pozitif işsizlik oranından ise negatif etkilenmektedir.
BANKA KREDİ HACMİ İLE EKONOMİK BÜYÜME ARASINDAKİ İLİŞKİ: DOĞRUSAL OLMAYAN EŞTÜMLEŞME ANALİZİ
Authors: Çelik İsmail Erkan , Kayacan Murad
Published: September 2023

Ekonomik büyüme ve finansal gelişme arasındaki ilişkinin ele alındığı araştırmaların önemli bir kısmında banka kredilerinde yaşanan genişleme sonucu ekonomik büyüme gerçekleştiği görülmektedir. Ancak aynı zamanda ekonomik büyümenin banka kredi hacmi üzerindeki etkisinin tespit edildiği çalışmalar da mevcuttur. Dolayısıyla henüz ilişki yapısının belirlenmesinde ortak bir fikir birliği olmadığını söylemek mümkündür. Buradan hareketle banka kredi hacminin ekonomik büyümeyi olumlu yönde etkilemesini amaçlayan para politikalarının etkinliği tartışmalı hale gelmektedir. Bu çalışmada amaç; Türkiye’nin ekonomik büyümesi için sabit sermaye toplamı, mevduat bankalarına ait toplam kredi hacmi, kamu mevduat bankaları kredi hacmi ve özel mevduat bankaları kredi hacmi arasındaki doğrusal olmayan eştümleşme ilişkisinin araştırılmasıdır. KSS (2006) eştümleşme testinde değişkenler arasında uzun dönemli bir eştümleşme ilişkisinin farklılaştığı tespit edilmiştir. Eştümleşmenin varlığından hareketle oluşturulan ESTAR hata düzeltme modeli mekanizmasının Türkiye’de GSYİH ve mevduat bankalarına ait toplam kredi hacmi modelinde çalıştığı sonucuna ulaşılarak ilgili literatüre öneriler getirilmiştir.
Тerminology of rectal cancer: consensus agreement of the expert working group
Authors: Berezovskaya Tatiana  P. , Rubtsova Natalia  A. , Sinitsyn Valentin  E. , Zarodnyuk Irina  V. , Nudnov Nicolai  V. , Mishchenko Andrei  V. , Trubacheva Yuliya  L. , Bergen Tatiana  A. , Grishko Pavel  Yu. , Balyasnikova Svetlana  S. , Dayneko Yana  A. , Ryjkova Darya  V. , Hodzhibekova Malika  M. , Rucheva Nataliya  A. , Turin Igor  E. , Achkasov Sergey  I. , Nevolskikh Alexey  A. , Gordeev Sergey  S. , Droshneva Inna  V.
Published: September 2023

Unified terminology is a necessary condition for successful interdisciplinary communication within the field of oncology. The variety of anatomical, pathomorphological, and clinical terms used in rectal cancer is often accompanied by their ambiguous interpretation both in domestic and foreign scientific literature. This not only complicates the interaction between specialists, but also complicates the comparison of the results of rectal cancer treatment obtained in different medical institutions.
Based on the analysis of recent domestic and international scientific and methodological literature on rectal cancer, the key terms used in the diagnosis and treatment planning of rectal cancer were selected, followed by a two-time online discussion of their interpretations by experts from the Russian Society of Radiologists and Therapeutic Radiation Oncologists, the Association of Oncologists of Russia, and the Russian Association of Therapeutic Radiation Oncologists until reaching consensus (80%) of experts on all items. Terms that fail to attain consensus were excluded in the final list.
A list of anatomical, pathomorphological, and clinical terms used in the diagnosis, staging, and treatment planning of rectal cancer has been compiled and, based on expert consensus, their interpretation has been determined.
A lexicon recommended in the description and formulation of the conclusion of diagnostic studies in patients with rectal cancer is proposed.
CMS - Intelligent Machine Translation with Adaptation and AI
Authors: Amin Ruhul , Mandapuram Mounika
Published: September 2023

Machine translation, an emerging breakthrough, has changed translation. Dictionary-based machine translation, computer-aided translation, and neural machine translation with AI as its fundamental technology have progressed. However, NMT with AI has advanced machine translation. Many translation concerns still need to be solved. Language changes with context and dialect. Artificial intelligence will enable systems with adaptive algorithms to collaborate with humans to translate content more efficiently and well. The human translation should be revised, according to some. All in all, human progress fixes faults. Neural networks in machine translation ensure that adaptive frameworks can interpret like human translators. AI still needs help with language training and translation. Given the diversity of linguistic patterns and civilizations, they address clever machines; even with AI, handling human productivity seems unlikely. Machine translation is an important NLP topic that uses computers and adaptive systems to understand standard dialects. Neural machine translation (NMT) has become the standard in real-world MT frameworks. We begin this study with a broad assessment of NMT strategies and discuss architecture, decoding, and data analysis to improve content translation. We then summarize the most helpful expert resources and tools. We conclude with a discussion of future paths.
Evaluation features of network quality and efficiency indicators of data transmission and traffic routing
Authors: Ланин М.А.
Published: September 2023

Проведен углубленный анализ показателей качества и эффективности сетевых систем. Выявлены существенные показатели качества сети передачи данных, определяющие степень ее пригодности для использования по назначению и влияющие на значения показателей эффективности. Систематизированы частные показатели эффективности функционирования сети, включая, наряду с результативностью, оперативностью и ресурсоемкостью, промежуточные показатели производительности и продуктивности, обладающие самостоятельной информативностью применительно к оцениванию эффективности сети. Обоснована целесообразность раздельного рассмотрения показателей технического качества сетей и качества обслуживания их пользователей.

An in-depth analysis of the quality and efficiency of network systems has been carried out. Significant indicators of the quality of the data transmission network have been identified, determining the degree of its suitability for its intended use and influencing the values of efficiency indicators. The article systematizes private indicators of the effectiveness of network, including, along with efficiency, speed and resource intensity, intermediate indicators of performance and productivity, which have independent informativeness in relation to evaluating the network efficiency. The expediency of separate consideration of indicators of the technical quality of networks and the quality of service for their users is substantiated.
Business-analysis and decision support system in information technologies
Authors: Селивонин А.Е.
Published: September 2023

Рассмотрены основные этапы сбора бизнес-требований для продукта, предлагаемого заказчику, роль бизнес-аналитика в ИТ-компаниях, экспертные системы, взаимодействие компанийразработчиков производимого продукта с B2C (Business to Client), B2B (Business to Business), B2B2C (Business to Business to Client). Показана целесообразность применения систем поддержки принятия решений в ИТ-компаниях, а также существующие ограничения в использовании. Важность данного исследования заключается в повышении эффективности управления проектами компании, которая определяется способностью предоставлять четкую информацию о задачах каждого сотрудника, прогнозировать возможные решения и альтернативы.

The article discusses the main stages of collecting business requirements for a product offered to a customer, the role of a business analyst in IT companies, expert systems in IT companies, the connection of a manufactured product with B2C, B2B, and B2B2C. The article shows the feasibility of using decision support systems in IT companies, as well as the existing limitations in use. The importance of this study lies in improving the efficiency of company project management, which is represented by the ability to provide clear information about the tasks of each employee and predict possible solutions and alternatives.
Method for organizing the microservice architecture of a modern Web application using the Istio service network
Authors: Кокотов Д.В.
Published: September 2023

По мере роста популярности сервисов в Интернете разработчикам все больше внимания необходимо уделять архитектуре приложения и используемым технологиям внутри системы. В данной статье сформулированы ключевые свойства современного web-приложения, необходимые для стабильной работы системы, безопасной передачи информации, а также даны гарантии высокого уровня предоставляемого сервиса. Рекомендована архитектура, позволяющая сформировать фундамент для достижения необходимых качеств системы. Рассмотрены некоторые способы физического размещения микросервисов на серверных компьютерах и предложено использовать контейнеры Docker как инструмент для эффективного запуска и масштабирования микросервисов. Но в процессе развития системы и повышения ее сложности требуется инструмент для управления множеством контейнеров, в связи с чем рекомендована платформа Kubernetes и описаны ее основные возможности. Также рассмотрены основные принципы подхода «сервисная сеть» и возможности его эффективной реализации в проекте Istio. Сервисная сеть Istio предоставляет дополнительные возможности для управления трафиком и безопасной передачи информации внутри платформы Kubernetes. Приведена общая схема архитектуры приложения на платформе Kubernetes с использованием сервисной сети Istio. Описаны ключевые достоинства и недостатки полученной архитектуры, примеры успешного использования выбранных технологий в промышленной среде.

As the popularity of services on the Internet grows, developers need to pay more and more attention to the architecture of the application and the technologies used within the system. This paper provides the key features of a modern web application, which are necessary for the stable operation of the system, the secure transfer of information, as well as gives guarantees of a high level of the service provided. An architecture is recommended that allows forming the foundation to achieve the necessary qualities of the system. The paper considers some ways of physical placement of microservices on server computers. As a result, it is proposed to use Docker containers as a tool for efficient deploing and scaling of microservices. But as the system evolves and becomes more complex, you will need a tool to manage multiple containers. To solve this problem, the Kubernetes platform is recommended and its main features are described. Further, the paper discusses the basic principles of the Service Mesh approach and its effective implementation in the Istio project. The Istio service mesh provides additional options for traffic management and secure communication within the Kubernetes platform. The last section of the paper is devoted a general diagram of the application architecture on the Kubernetes platform using the Istio service mesh. The key advantages and disadvantages of the resulting architecture are described as well as the examples of successful use of selected technologies in an industrial environment.
Basic typing of multibit microprocessor in the structure of modern microprocessors
Authors: Приходько Д.И.
Published: September 2023

Рассматриваются мультиразрядные микропроцессы – особый класс значительно улучшенных микропроцессоров, в которые встроены механизмы, отвечающие за повышение надежности работы программного обеспечения, запускаемого на данном микропроцессоре, – табличная структура регистров и система резервного копирования. Рассматривается месторасположение указанного микропроцессора и основные характеристики модельного ряда: система команд (самые популярные типы CISC и RISK), тип организации стэка (Неймана – Лебедева, гарвардская архитектура), тип распределения команд (статический или динамический). В качестве примера взят доработанный вариант микропроцессора AMD64, в котором применена табличная модель организации регистров и использовано резервное копирование.

The article considers a special class of microprocessors – multi-bit microprocessors, which are significantly improved microprocessors. They have built-in mechanisms to improve the reliability of software running on a given microprocessor. The main ones are a tabular register structure, and a backup system. The location of the specified microprocessor and the main characteristics of the lineup are considered, which include the command system (the most popular CISC and RISK types), the type of stack organization (Neumann – Lebedev, Harvard architecture), the type of command distribution (static or dynamic). An example for an analysis will be a modified version of the AMD64 microprocessor, in which a tabular model of register organization is applied and backup is used.
Analytic modeling of the thermal field behavior in case of radial and linear filtration in the near-wellbore area
Authors: Батманова О.В. , Наумов А.С. , Ерастова В.А. , Никонорова А.Н. , Гуляев Д.Н.
Published: September 2023

Динамика теплового поля в эксплуатационных скважинах при разработке месторождений углеводородов несет в себе большой объем полезной информации, благодаря чему можно оценить состояние околоскважинного пространства. Данная информация крайне полезна для задач разработки нефтегазовых месторождений. Методы геофизических исследований скважин часто используют термометрию для оценки состояния прискважинной области, где потенциально можно выявлять наличие трещин в горной породе или же в цементном кольце скважин. Данные разновидности каналов могут быть задействованы в явлении непроизводительной закачки, выражающемся в том, что вода вместо целевого объекта нагнетания уходит в нецелевые пласты. Важно корректно диагностировать тип канала, имеющийся в околоскважинной зоне, поскольку от этого зависит, какой тип ремонтных работ следует использовать для ликвидации перетока В работе рассматривается аналитическое моделирование поведения теплового поля в скважине для случаев радиальной и линейной фильтрации в пористой среде.

The dynamics of the temperature field in oil wells for hydrocarbon fields development carries a large amount of useful information, due to which it is possible to evaluate the state of the near-wellbore layers. This information is extremely useful for the purpose of oil and gas field development. Production logging techniques often use temperature logs to evaluate the near-wellbore area, where the presence of fractures in the rocks or well cement can be potentially detected. These types of fractures can be involved in the phenomenon of unproductive injection, where injected water instead of going to the target formations goes into non-target formations. It is important to correctly diagnose the type of behind the casing crossflows in the near-wellbore zone, as this will determine which type of workovers should be used for crossflows elimination. The paper considers analytical modeling of the temperature field behavior in a well for the cases of radial and linear filtration in a porous medium.
Modeling the impact of bending deformation in a singlemode optical fiber on the refractive index of core – shell
Authors: Резак Е.В.
Published: September 2023

Рассматривается модель деформированного одномодового оптического волокна. Приводится математическая модель деформационных составляющих. Произведена оценка показателей преломления в трех взаимно перпендикулярных направлениях. Найдены случаи, в которых распространение света по изогнутому волокну происходит как по одноосному кристаллу. Определено, что значения показателя преломления изогнутого оптического волокна отличаются от показателя преломления недеформированного волокна.

The article addresses the model of a deformed single-mode optical fiber. A mathematical model of deformation fibers is given. Cases have been found where the propagation of light along a bent fiber occurs as though along a uniaxial crystal. A certain value of the refractive index of a bent optical fiber differs from the refractive index of the undeformed fiber.
Methodology for identifying and tracking social media misinformation in tweets about the impact of the COVID-19 pandemic on reproductive health
Authors: Золотарев О.В. , Хакимова А.Х. , Агравал Ш. , Джейн С.К. , Каушал С.
Published: September 2023

Цель исследования заключалась в разработке методики выявления и отслеживания дезинформации в социальных сетях, в частности в Твиттере, о влиянии коронавируса и COVID-вакцины на репродуктивное здоровье, одной из причин чего является недостаточная информированность об аспектах коронавирусной инфекции. Мы используем сочетание машинных и экспертных методов, последние научные статьи как эталон выявления дезинформации. Предлагаемая методика включает в себя изучение научных статей как источника достоверной правдивой информации по теме (стандарт информации) и сообщений в Твиттере (оценка соответствия информации стандарту). Результатом исследования является методика выявления дезинформации в сообщениях пользователей социальной сети. На основе этой методологии разработаны следующие аспекты проблемы: 1) формирование научного стандарта; 2) принцип сопоставления направлений научных исследований и дискуссий в Твиттере; 3) принцип контекстуального сопоставления пользовательского и научного представлений о проблемах. В отличие от существующих работ, сформулированы принципы, основанные на обработке информации из содержания научных статей и сообщений в социальных сетях.

The purpose of the study was to develop a methodology for identifying and tracking social media misinformation in tweets about the impact of the coronavirus and COVID-vaccine on reproductive health, one of the reasons for which is the lack of awareness about aspects of the coronavirus infection. We use a combination of machine and expert methods, the latest scientific articles as the standard for detecting disinformation. The proposed methodology includes the study of scientific articles as a source of reliable truthful information about the topic (information standard) and Twitter messages (assessment of information compliance with the standard). The result of the study is the methodology for detecting disinformation in the messages of social network users. Based on this methodology, the following aspects of the problem have been developed: 1) the formation of a scientific standard; 2) the principle of comparing the directions of scientific research and discussions on Twitter; 3) the principle of contextual comparison of user and scientific ideas about problems. In contrast to the existing works, the principles based on the information from the content of scientific articles and messages from social networks processing are formulated.
Mixed Poisson Transmuted New Weighted Exponential Distribution with Applications on Skewed and Dispersed Count Data
Authors: ADETUNJI Ademola Abiodun , Sabri Shamsul Rijal Muhammad
Published: September 2023

In this study, a new three-parameter mixed Poisson Cubic Rank Transmuted New Weighted Exponential Distribution is proposed. The new discrete distribution is obtained by mixing the Poisson distribution with a newly obtained Cubic Rank Transmuted New Weighted Exponential Distribution. Various shapes and mathematical properties of both mixing distribution and the new count distribution are examined. Special cases of the new proposition are also identified. The distribution along with its special cases and other count distributions are assumed for skewed and dispersed count observations. The maximum likelihood estimation is used to provide estimates for the parameters of all examined distributions. Results show that the new proposition along with some of its special cases provide good fit for all the examined data.
Marginal and Conditional both Extreme Value Distributions: A Case of Stochastic Regression Model
Authors: Bharali Sulaxana , Hazarika Jiten , Goswami Kuldeep
Published: September 2023

A mathematical model is a mathematical connection that describes some real-life scenario. To handle real-world problems securely and effectively, simulation modelling is required. In this article, the author investigates the stochastic regression model scenario in which the dependent and independent variables in a linear regression model follow a distribution. We assume that the dependent and independent variables both exhibit Type I Extreme Value Distribution. The estimators are then derived using the Modified Maximum Likelihood (MML) estimation method. In accordance with this, a hypothesis testing technique is developed.
Combined intravenous and intraarticular tranexamic acid compared with intraarticular use alone in total knee arthroplasty: A randomized controlled trial
Authors: Minaei Reza , Kazemi Seyed Morteza , Hoseini Seyyed Mehdi , Mirahmadi Alireza , Hosseini-Monfared Pooya , Salimi Maryam
Published: September 2023

: Total knee arthroplasty is associated with high rates of blood loss during and after the surgery. Tranexamic acid is an antifibrinolytic agent that effectively reduces total blood loss in total knee arthroplasty and minimizes the need for blood transfusion and transfusion-related complications. However, the most efficacious route of tranexamic acid administration has not been established. Therefore, in this study, we aimed to compare combined intravenous and intraarticular tranexamic acid with intraarticular use alone in patients undergoing total knee arthroplasty.

In this randomized, double-blind clinical trial, 104 patients scheduled for primary unilateral Total knee arthroplasty were randomized to one of the two intervention groups. The combined intravenous and intraarticular group received 15 mg/kg (Max dose of 1 g) of intravenous tranexamic acid along with 15 mg/kg (Max dose of 1 g) of tranexamic acid administered intraarticularly after the capsule and retinaculum closure. Total blood loss was calculated using the drop in hemoglobin at post-operative day 3. The transfusion rate and incidence of thromboembolic events were evaluated.

Total blood loss in patients receiving combined intravenous and intraarticular tranexamic acid was not significantly different from that in patients receiving only intraarticular tranexamic acid (926 ± 312 ml vs 905 ± 348 ml, p value= 0.824). There were no complications like thromboembolic events or wound infection.

In conclusion, the intraarticular administration of tranexamic acid is an equally effective route as combined intravenous and intraarticular use of tranexamic acid in total knee arthroplasty, and hence to avoid potential complications of systemic TXA use, we recommend using the intraarticular only tranexamic acid in total knee arthroplasty.
Firecracker (Sutli Bomb) explosion in hand and Diwali celebration: A unique case
Authors: Makkar Dheeraj , Sauhta Ravi
Published: September 2023

This case report focuses on the management and treatment of a ten-year-old boy who suffered extensive hand injuries from a live firecracker explosion during Diwali celebrations. The purpose of the report is to highlight the importance of caution when handling fireworks and to present the approach taken in managing the patient's injuries.

The patient underwent a comprehensive assessment, and a treatment plan was formulated. The plan included exploration and debridement, conservative management, thumb and index finger fixation, posterior interosseous flap surgery, and wrist stabilization with JESS. Additionally, a contracture release procedure was performed to address finger contracture. The patient received physical rehabilitation for hand functionality restoration.

The case report emphasizes the significance of handling fireworks with care and the need for immediate medical attention in the event of injuries. The successful outcome achieved through the implemented treatment plan underscores the importance of prompt and appropriate management in fireworks-related accidents.
A screening strategy to prevent hospital acquired COVID -19 in peak pandemic period
Authors: Garg Jaya , Agarwal Jyotsna , Singh Mridu , Das Anupam , Sen Manodeep
Published: September 2023

Health care worker (HCW) are at increased risk for Severe acute respiratory syndrome corona virus 2 (SARSCoV-2) infection. The study evaluates seroprevalence of SARS CoV-2 IgG antibody among HCW during peak pandemic period and plans a screening strategy for early identification and isolation of HCW.

This is the prospective cross sectional study of HCW where High risk and low risk HCW were tested for the presence of SARS-CoV-2 IgG antibodies using Architect automated analyser.

Out of 264 HCW, 36 (13.6%) HCW were positive for SARS CoV-2 IgG antibodies. Seroprevalence was 14.7% in low risk group while 13.2 % among high risk group. Serosurvey could detect antibody in 47.3% HCW which were either negative by COVID-19 RTPCR or were never tested owing to absence of clinical symptoms.SARS-CoV-2 IgG antibody were absent in 39% previously COVID-19 positive HCW.

Equal seroprevalence in both the groups of HCW during peak of pandemic is suggestive of community transmission in India and robust infection control policy of hospital. Also, we conclude that there is need of multiprong approach with serial diagnostic screening of COVID infection in health care worker which should include both RTPCR and serological test.
Turkey ear as a cutaneous manifestation of tuberculosis
Authors: Pandey Ayush , Poorvi  , Bhardwaj Mohit
Published: September 2023

Lupus vulgaris is the most common morphological variant of cutaneous tuberculosis. Classical lupus lesions are often seen in the head and neck region. Turkey ear is a clinically descriptive term, previously being used for the earlobe with reddish indurated plaque lesions, which recently can be a sign for lupus vulgaris.
Instituições, evolução institucional e historiografia econômica: a contribuição de Douglass North
Authors: Da Costa Eduardo José Monteiro
Published: September 2023

Este artigo tem por objetivo apresentar os elementos centrais dateoria das instituições desenvolvida por Douglass North para a compreensãoda dinâmica econômica em sua perspectiva histórica. Para isso, apresenta ascontribuições seminais para o debate, descreve na forma de survey a evolução de seu pensamento no que tange a importância das instituições, e apresenta a teoria institucionalista de North em sua visão consolidada, destacando os conceitos mais importantes e o papel da mudança institucional na historiografia econômica
Vamos falar sobre africanidade? universidade, geografia e identidade numa comunidade quilombola amazônica
Authors: Marques Indira Cavalcante Rocha , Trindade Anna Thereza Correa
Published: September 2023

O artigo relata a experiência de um projeto da Faculdade de Geografia da UFPA/Belém, que desenvolveu ações junto ao território quilombola de Jambuaçu, no município de Moju, Pará. Espaço, território e lugar foram os conceitos geográficos que, associados às elaborações de Paulo Freire, se colocaram em diálogo com a realidade vivida pelos moradores locais para estimular os estudantes da comunidade a ressignificarem o olhar sobre sua identidade. Isso foi estruturado em torno de uma oficina cujos momentos centrais foram a dinâmica “Teia territorial da vida” e a gincana “Construa sua representação”. Ao final, os estudantes constataram que os diversos elementos da realidade local estão interligados, de modo que a interferência de um empreendimento mineral, por exemplo, pode alterar significativamente a dinâmica comunitária. Também perceberam a necessidade de valorização de sua identidade quilombola como parte da defesa de seu território.
Saúde e habitação: enfrentamentos para o tratamento domiciliar na diálise peritoneal
Authors: Souza Luana Caroline de Matos
Published: September 2023

O presente estudo visa relatar os enfrentamentos do paciente renal crônico para o tratamento domiciliar na modalidade de diálise peritoneal. O estudo foi motivado a partir da experiência como assistente social residente no setor de nefrologia de um hospital de alta complexidade no estado do Pará, observou-se durante atendimentos sociais as muitas dificuldades enfrentadas por grande parte dos pacientes em admissão na diálise peritoneal, no que se refere à adequação de sua casa para realização do tratamento. O método de pesquisa utilizado pauta-se no estudo de caso único de um paciente de diálise peritoneal que teve seu início no tratamento completamente influenciado por sua situação habitacional, os dados foram coletados por meio de entrevista com o usuário, assim como consulta ao seu prontuário. Constatou-se que os enfrentamentos para o tratamento domiciliar em diálise peritoneal são condicionados pela desigualdade social e escassez de efetivação de políticas públicas, constatou-se também que a promoção da saúde está inteiramente ligada às condições habitacionais, sendo necessário promover a saúde compreendendo especificidades sociais e regionais.
Conservação do patrimônio cultural e turismo no vale do tapajós: perspectivas e possiblidades em Fordlândia/PA
Authors: Figueira Sahyra Soares , Cruz Silvia Helena Ribeiro , Campos Raul Ivan Raiol de
Published: September 2023

Na década de 1920, Fordlândia foi um grande empreendimento no Tapajós concebida para atender as necessidades da indústria automobilística da Companhia Ford. Ressaltar a importância da conservação do seu patrimônio cultural, assim como a importância do turismo para o desenvolvimento de Fordlândia é objetivo deste artigo, que utilizou como embasamento pesquisas bibliográfica, documental e pesquisa de campo, com técnica qualitativa com observações e entrevistas. O referido estudo aponta como resultados a necessidade de maior incentivo, capacitação e orientação da população de Fordlândia no que diz respeito à conservação do seu patrimônio. Estas tarefas podem ser associadas a ações de educação patrimonial com o turismo, podendo ser aliadas à informação e à conservação patrimonial, com possibilidade de ser um agente de transformação quando bem planejado, criando nas pessoas um orgulho pertencer àquela comunidade. Ao criar-se o sentimento de pertencimento, o turismo pode se valer de ações que visem a criar nas pessoas a consciência de maior zelo e proteção do seu patrimônio cultural. A conservação do patrimônio cultural de Fordlândia se faz necessária e urgente, sendo este o meio mais eficaz para evitar a degradação destes bens. Embora Fordlândia ainda tenha um turismo sem planejamento reúne no seu patrimônio e sua história, condições de se tornar de modo oficial um roteiro cultural no Tapajós, sendo necessário para tal, maiores investimentos no que diz respeito à infraestrutura, sendo importante garantir melhorias não só aos turistas, mas à população como um todo
QUEM FAZ E ONDE ESTÁ A PRODUÇÃO ACADÊMICA ETNOBOTÂNICA EM COMUNIDADES QUILOMBOLAS DA MATA ATLÂNTICA?
Authors: De Morais Bianca Pinto , Gonçalves Maiara Cristina , Hanazaki Natalia
Published: September 2023

O objetivo deste trabalho foi apresentar os principais aspectos da pesquisa etnobotânica em quilombos da Mata Atlântica a partir de uma perspectiva étnico-racial. O desenvolvimento de pesquisas etnobotânicas brasileiras tem apresentado importantes avanços nas últimas décadas tanto em relação à diversidade de publicações como também em relação às questões éticas; neste sentido, o questionamento sobre o racismo institucional na pesquisa etnobotânica busca discutir questões sociais latentes em nossa sociedade que refletem também nas relações entre pesquisadores e colaboradores durante o desenvolvimento da pesquisa e que se apoiam no mito da identidade coletiva nacional e da neutralidade científica. A partir de uma revisão sistemática em bases indexadas (Scopus e Web of Science), foram padronizados dados oriundos de 89 estudos publicados entre 1988 e 2020, compreendendo mais de 1000 entradas de informações que, após filtragens por repetições e inconsistências, resultaram numa compilação de 15 artigos publicados sobre usos de 380 espécies de plantas. As principais categorias citadas foram medicinais e alimentícias. Nove pessoas autoras responderam a um questionário online, com perguntas sobre seu perfil pessoal e sobre as motivações para o desenvolvimento do estudo em comunidades remanescentes de quilombos. Os estudos confirmam a enorme diversidade de espécies e de usos pelas comunidades quilombolas, contudo também indicam hegemonia das pessoas que produzem o conhecimento científico, realizado por mulheres em sua maioria branca demonstrando a importância das discussões sobre gênero e branquitude nas pesquisas etnobotânicas.