bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on magnetic excitation model of magnetic flux leakage for coal mine hoisting wire rope
Authors: Tian Jie , Wang Hongyao
Published: December 2015

This study presents the optimal design of a magnetic excitation model for developing a nondestructive sensor for coal mine hoist wire ropes. The model was established using axial-symmetry finite-element analysis and calculations. The influence of the excitation device parameters on the local magnetization effect of the wire rope was investigated in detail using the axial-symmetry finite-element model. The excitation model parameters of the sensor were optimally designed using a combination of finite-element analysis and an optimization method. The experiments were performed to measure the leakage flux and evaluate the performance of the optimally designed sensor. The results show that the sensor based on the newly designed excitation model can not only improve the signal-to-noise ratio for defect detection in a coal mine hoist wire rope by 11% compared to an existing sensor but also reliably detect small defects with a high detection speed (5 m/s) along the length of the coal mine wire rope.
Improving Clinical Outcomes of Very Low Birth Weight Infants by Early Standardized Nutritional Management
Authors: Shakeel Fauzia , Napolitano Anthony , Newkirk Melanie , Harris Jo Ellen , Ghazarian Sharon R.
Published: December 2015

Background. Optimal nutrition for very low birth weight (VLBW, <1500 grams) preterm infants is critical in the neonatal period. With substantial variation in clinical practice, there is limited data on impact of early nutrition on growth and outcomes. Objective. The purpose of this study was to conduct a quality improvement project evaluating growth and clinical outcomes after implementing standardized enteral feeding guidelines for preterm infants. Methods. Evidence based clinical practice feeding guidelines were developed and implemented for VLBW infants in NICU. Primary outcome measures were (1) the rate of early initiation of enteral feeds (< 5 days of life) and (2) growth outcomes as measured by weight and head circumference from birth to discharge. Secondary outcome measures were total TPN days and rate of cholestasis. Retrospective data prior to initiation of guidelines were compared with data from post-implementation period in logistic and linear regression models. Results. Pre and post-implementation cohorts consisted of 121 and 114 VLBW infants respectively. Standardized guidelines resulted in early initiation of enteral feeds by day 5 (OR = 3.57; p< 0.001) and an average weight gain >20gm/day during hospital stay (OR= 1.89; p< 0.05). In both groups there was early achievement of full feeds with early initiation of feeds (p<0.001). Similarly, infants who initiated early enteral feeds were less likely to develop cholestasis (direct bilirubin >2 mg/dl) (p<0.01) Conclusions. Consistent and standardized approach to early nutrition in VLBW infants results in improved growth and clinical outcomes with less duration of TPN and decreased rate of cholestasis.
The burden of comorbidity in people with chronic kidney disease stage 3: a cohort study
Authors: Fraser Simon D. S. , Roderick Paul J. , May Carl R. , McIntyre Natasha , McIntyre Christopher , Fluck Richard J. , Shardlow Adam , Taal Maarten W.
Published: December 2015

Background

Multimorbidity is a growing concern for healthcare systems, with many countries experiencing demographic transition to older population profiles. Chronic kidney disease (CKD) is common but often considered in isolation. The extent and prognostic significance of its comorbidities is not well understood. This study aimed to assess the extent and prognostic significance of 11 comorbidities in people with CKD stage 3.

Methods

A prospective cohort of 1741 people with CKD stage 3 was recruited from primary care between August 2008 and March 2010. Participants underwent medical history, clinical assessment, blood and urine sampling. Comorbidity was defined by self-reported doctor-diagnosed condition, disease-specific medication or blood results (hemoglobin), and treatment burden as number of ongoing medications. Logistic regression was used to identify associations with greater treatment burden (taking >5 medications) and greater multimorbidity (3 or more comorbidities). Kaplan Meier plots and multivariate Cox proportional hazards models were used to investigate associations between multimorbidity and all-cause mortality.

Results

One thousand seven hundred forty-one people were recruited, mean age 72.9 +/−9 years. Mean baseline eGFR was 52 ml/min/1.73 m2. Only 78/1741 (4 %) had no comorbidities, 453/1741 (26 %) had one, 508/1741 (29 %) had two and 702/1741 (40 %) had >2. Hypertension was common (88 %), 30 % had ‘painful condition’, 24 % anemia, 23 %, ischaemic heart disease, 17 % diabetes and 12 % thyroid disorders. Median medication use was 5 medications (interquartile range 3–8) and increased with degree of comorbidity. Greater treatment burden and multimorbidity were independently associated with age, smoking, increasing body mass index and decreasing eGFR. Treatment burden was also independently associated with lower education status. After median 3.6 years follow-up, 175/1741 (10 %) died. Greater multimorbidity was independently associated with mortality (hazard ratio 2.81 (95 % confidence intervals 1.72–4.58), p < 0.001) for 3 or more comorbidities vs 0 or 1).

Conclusions

Isolated CKD was rare and multimorbidity the norm in this cohort of people with moderate CKD. Increasing multimorbidity was associated with greater medication burden and poorer survival. CKD management should include consideration of comorbidities.
CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma
Authors: Mitsui Yozo , Chang Inik , Fukuhara Shinichiro , Hiraki Miho , Arichi Naoko , Yasumoto Hiroaki , Hirata Hiroshi , Yamamura Soichiro , Shahryari Varahram , Deng Guoren , Wong Darryn K. , Majid Shahana , Shiina Hiroaki , Dahiya Rajvir , Tanaka Yuichiro
Published: December 2015

Background

Cytochrome P450 1B1 (CYP1B1) has been shown to be up-regulated in many types of cancer including renal cell carcinoma (RCC). Several reports have shown that CYP1B1 can influence the regulation of tumor development; however, its role in RCC has not been well investigated. The aim of the present study was to determine the functional effects of CYP1B1 gene on tumorigenesis in RCC.

Methods

Expression of CYP1B1 was determined in RCC cell lines, and tissue microarrays of 96 RCC and 25 normal tissues. To determine the biological significance of CYP1B1 in RCC progression, we silenced the gene in Caki-1 and 769-P cells by RNA interference and performed various functional analyses.

Results

First, we confirmed that CYP1B1 protein expression was significantly higher in RCC cell lines compared to normal kidney tissue. This trend was also observed in RCC samples (p < 0.01). Interestingly, CYP1B1 expression was associated with tumor grade and stage. Next, we silenced the gene in Caki-1 and 769-P cells by RNA interference and performed various functional analyses to determine the biological significance of CYP1B1 in RCC progression. Inhibition of CYP1B1 expression resulted in decreased cell proliferation, migration and invasion of RCC cells. In addition, reduction of CYP1B1 induced cellular apoptosis in Caki-1. We also found that these anti-tumor effects on RCC cells caused by CYP1B1 depletion may be due to alteration of CDC20 and DAPK1 expression based on gene microarray and confirmed by real-time PCR. Interestingly, CYP1B1 expression was associated with CDC20 and DAPK1 expression in clinical samples.

Conclusions

CYP1B1 may promote RCC development by inducing CDC20 expression and inhibiting apoptosis through the down-regulation of DAPK1. Our results demonstrate that CYP1B1 can be a potential tumor biomarker and a target for anticancer therapy in RCC.
Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes
Authors: Qin Harry H. , Filippi Céline , Sun Song , Lehec Sharon , Dhawan Anil , Hughes Robin D.
Published: December 2015

Introduction

Mesenchymal stem/stromal cells (MSCs) improve the metabolic function of co-cultured hepatocytes. The present study aimed to further enhance the trophic effects of co-culture with hepatocytes using hypoxic preconditioning (HPc) of the MSCs and also to investigate the underlying molecular mechanisms involved.

Methods

Human adipose tissue-derived MSCs were subjected to hypoxia (2 % O2; HPc) or normoxia (20 % O2) for 24 h and then co-cultured with isolated human hepatocytes. Assays of metabolic function and apoptosis were performed to investigate the hepatotrophic and anti-apoptotic effects of co-culture. Indirect co-cultures and co-culture with MSC-conditioned medium investigated the role of paracrine factors in the hepatotrophic effects of co-culture. Reactive oxygen species (ROS) activity was antagonised with N-acetylcysteine to investigate whether HPc potentiated the effects of MSCs by intracellular ROS-dependent mechanisms. Tumour necrosis factor (TNF)-α, transforming growth factor (TGF)-β1, and extracellular collagen production was determined and CASP9 and BAX/BCL-2 signalling pathways analysed to investigate the role of soluble factors, extracellular matrix deposition, and apoptosis-associated gene signalling in the effects of co-culture.

Results

HPc potentiated the hepatotrophic and anti-apoptotic effects of co-culture by ROS-dependent mechanisms. There was increased MSC TGF-β1 production, and enhanced MSC deposition of extracellular collagen, with reduced synthesis of TNF-α, as well as a downregulation of the expression of pro-apoptotic CASP9, BAX, BID and BLK genes and upregulated expression of anti-apoptotic BCL-2 in hepatocytes.

Conclusions

HPc potentiated the trophic and anti-apoptotic effects of MSCs on hepatocytes via mechanisms including intracellular ROS, autocrine TGF-β, extracellular collagen and caspase and BAX/BCL-2 signalling pathways.
Neural and mesenchymal stem cells in animal models of Huntington’s disease: past experiences and future challenges
Authors: Kerkis Irina , Haddad Monica Santoro , Valverde Cristiane Wenceslau , Glosman Sabina
Published: December 2015

Huntington’s disease (HD) is an inherited disease that causes progressive nerve cell degeneration. It is triggered by a mutation in the HTT gene that strongly influences functional abilities and usually results in movement, cognitive and psychiatric disorders. HD is incurable, although treatments are available to help manage symptoms and to delay the physical, mental and behavioral declines associated with the condition. Stem cells are the essential building blocks of life, and play a crucial role in the genesis and development of all higher organisms. Ablative surgical procedures and fetal tissue cell transplantation, which are still experimental, demonstrate low rates of recovery in HD patients. Due to neuronal cell death caused by accumulation of the mutated huntingtin (mHTT) protein, it is unlikely that such brain damage can be treated solely by drug-based therapies. Stem cell-based therapies are important in order to reconstruct damaged brain areas in HD patients. These therapies have a dual role: stem cell paracrine action, stimulating local cell survival, and brain tissue regeneration through the production of new neurons from the intrinsic and likely from donor stem cells. This review summarizes current knowledge on neural stem/progenitor cell and mesenchymal stem cell transplantation, which has been carried out in several animal models of HD, discussing cell distribution, survival and differentiation after transplantation, as well as functional recovery and anatomic improvements associated with these approaches. We also discuss the usefulness of this information for future preclinical and clinical studies in HD.
Fixed point theorems for set-valued mappings on TVS-cone metric spaces
Authors: Fierro Raúl
Published: December 2015

In the context of TVS-cone metric spaces, we prove a Bishop-Phelps and a Caristi type theorem. These results allow us to prove a fixed point theorem for $(\delta, L)$
(
δ
,
L
)
-weak contraction according to a pseudo Hausdorff metric defined by means of a cone metric.
Strong convergence theorems for the split equality variational inclusion problem and fixed point problem in Hilbert spaces
Authors: Guo Haili , He Huimin , Chen Rudong
Published: December 2015

In this paper, we propose and investigate two new iterative algorithms for solving the split equality variational inclusion problem in Hilbert spaces. We also prove that the sequences generated by the proposed algorithms converge strongly to a common solution of the split equality variational inclusion problem and fixed points of a family of nonexpansive mappings, which is also an unique solution of a variational inequality as an optimality condition for a minimization problem. The results presented in this paper extend and generalize a variety of existing results in this area.
H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa
Authors: Baichoo Shakuntala , Botha Gerrit , Jaufeerally-Fakim Yasmina , Mungloo-Dilmohamud Zahra , Lundin Daniel , Mulder Nicola , Promponas Vasilis J. , Ouzounis Christos A.
Published: December 2015

In the context of recent international initiatives to bolster genomics research for Africa, and more specifically to develop bioinformatics expertise and networks across the continent, a workshop on computational metagenomics was organized during the end of 2014 at the University of Mauritius. The workshop offered background on various aspects of computational biology, including databases and algorithms, sequence analysis fundamentals, metagenomics concepts and tools, practical exercises, journal club activities and research seminars. We have discovered a strong interest in metagenomics research across Africa, to advance practical applications both for human health and the environment. We have also realized the great potential to develop genomics and bioinformatics through collaborative efforts across the continent, and the need for further reinforcing the untapped human potential and exploring the natural resources for stronger engagement of local scientific communities, with a view to contributing towards the improvement of human health and well-being for the citizens of Africa.
Influence of phytochemicals in piper betle linn leaf extract on wound healing
Authors: Lien Le Thi , Tho Nguyen Thi , Ha Do Minh , Hang Pham Luong , Nghia Phan Tuan , Thang Nguyen Dinh
Published: December 2015

Background

Wound healing has being extensively investigated over the world. Healing impairment is caused by many reasons including increasing of free-radicals-mediated damage, delaying in granulation tissue formation, reducing in angiogenesis and decreasing in collagen reorganization. These facts consequently lead to chronic wound healing. Piper betle Linn (Betle) leaves have been folklore used as an ingredient of drugs for cutaneous wound treatment. However, the effect of betle leaf on wound healing is not yet well elucidated. In this study, we aimed to investigate the healing efficacy of methanol leaf extract of Piper betle Linn on proliferation of fibroblast NIH3T3 cells as well as full-thickness burn and excision wounds in swiss mice.

Methods

Scratch wound healing assays were conducted to examine the effects of betle leaf extract on healing activity of fibroblast cells. Burn and excision wounds on swiss mouse skins were created for investigating the wound healing progress caused by the betle leaf extract. Malondialdehyde (MDA) was also evaluated to examine the products of lipid hydroperoxide (LPO) under conditions of with or without betle leaf extract treatment.

Results

The results of this study showed that Piper betle Linn leaf extract in methanol increased proliferation of NIH3T3 cells and promoted wound healing in vitro and in vivo with both burn wound and excision wound models. In addition, this extract significant decreased level of malondialdehyde (MDA) in liver of treated-mice compared with that in non-treated mice.

Conclusions

Our results suggest that Piper betle Linn can be used as an ingredient in developing natural origin drugs for treatment of cutaneous wounds.
Editorial: Ephs, ephrins, and early T cell development
Authors: Bryson Jerrod L , Bhandoola Avinash
Published: December 2015

Discussion of how Eph-ephrin signaling is required for efficient generation of the ETP.
Editorial: Breaching their way through: Neutrophils destroy intercellular junctions to transmigrate rapidly across lymphatic endothelium
Authors: Teijeira Alvaro , Halin Cornelia
Published: December 2015

Discussion on the molecular and cellular mechanism of neutrophil migration across lymphatic endothelium compared to dendritic cell migration.
The liver sinusoidal endothelium reappears after being eclipsed by the Kupffer cell: a 20th century biological delusion corrected
Authors: Anderson Clark L
Published: December 2015

Attention returns to the robust scavenging properties of the liver sinusoidal endothelium.
Health inequalities and psychosis: Time for action
Authors: Shiers David , Bradshaw Tim , Campion Jonathan
Published: December 2015

People with psychosis face a life-restricting and life-shortening epidemic of obesity, diabetes and cardiovascular disease. This can be predicted by the associated antecedent risk factors evident from early in psychosis, yet remain largely ignored. Greater coordination between primary care, secondary care and public health to systematically prevent and intervene earlier for these physical illnesses offers a realistic solution to reduce this health inequality.
Commissioning neuropsychiatry services: barriers and lessons
Authors: Bhattacharya Rahul , Rickards Hugh , Agrawal Niruj
Published: December 2015

Aims and method

Previous studies have shown variations in commissioning of neuropsychiatry services and this makes access to neuropsychiatric services a postcode lottery. In this survey, we approached all mental health and neuropsychiatric service commissioners within London to map current funding and commissioning arrangements, and explored perceived barriers to neuropsychiatric service commissioning.

Results 83% of commissioners within London responded. There was significant variability between neuropsychiatric services commissioned through the mental health stream. Contracting arrangements were variable. Lack of earmarked fund for neuropsychiatry and disjointed funding stream for such services were identified by commissioners as a barrier, as was the critical mass of neuropsychiatric cases.

Clinical implications

Neuropsychiatric service development continues to be hindered by lack of clear commissioning process. Strategic drive is needed to promote more equitable neuropsychiatric services. National or regional commissioning covering a large population will provide a better model for neuropsychiatric services to be commissioned.
Mental health problems associated with female genital mutilation
Authors: Knipscheer Jeroen , Vloeberghs Erick , van der Kwaak Anke , van den Muijsenbergh Maria
Published: December 2015

Aims and method

To study the mental health status of 66 genitally mutilated immigrant women originating from Africa (i.e. Somalia, Sudan, Eritrea and Sierra Leone). Scores on standardised questionnaires (Harvard Trauma Questionnaire-30, Hopkins Symptom Checklist-25, COPE-Easy, Lowlands Acculturation Scale) and demographic and psychosocial correlates were analysed.

Results

A third of the respondents reported scores above the cut-off for affective or anxiety disorders; scores indicative for post-traumatic stress disorder were presented by 17.5% of women. Type of circumcision (infibulation), recollection of the event (a vivid memory), coping style (avoidance, in particular substance misuse) and employment status (lack of income) were significantly associated with psychopathology.

Clinical implications

A considerable minority group, characterised by infibulated women who have a vivid memory of the circumcision and cope with their symptoms in an avoidant way, reports to experience severe consequences of genital circumcision. In terms of public healthcare, interventions should target these groups as a priority.
The changing face(book) of psychiatry: can we justify ‘following’ patients' social media activity?
Authors: Cox-George Chantal
Published: December 2015

Individuals with mental health issues may post information on social networking sites that can provide an insight into their mental health status. It could be argued that doctors (and specifically psychiatrists) should understand the way in which social media is used by their patients to gain a better insight into their illnesses. However, choosing to actively monitor a patient's social media activity raises important questions about the way in which medical students, qualified clinicians and other healthcare professionals obtain information about patients. While this may be framed as a mere form of ‘collateral history-taking’, there are obvious practical and ethical problems with doing so. Here, a case is made against monitoring the social media activity of patients involved with psychiatric services.
Emergent Precarities and Lateral Aesthetics
Authors: Adan Elizabeth , Bateman Benjamin
Published: December 2015

This introduction to the special focus section, “Emergent Precarities and Lateral Aesthetics,” takes the recent work of Lauren Berlant and Judith Butler as its point of departure to map the parameters of lateral agency and precarity as a means of exploring what options are available for artistic and cultural projects that attempt to imagine their way through, and/or intervene in, the neoliberal forces producing these attritions in, and of, labor and life. Drawing from certain developments in postwar avant-garde art and culture (e.g., Debord's notion of drift) as well as more recent investigations in art, aesthetics, and politics (e.g., Rancière's notion of indeterminacy), this essay proposes that new habits of attenuation, diminution, and collective de-dramatization, along with new modes of perception — to which “emergent precarities” and “lateral aesthetics” offer a tentative name — serve as options for projects in literature, visual art, and related modes of cultural production that work to describe, investigate, and at times interrupt the conditions of neoliberalism.
Unstored Energies
Authors: François Anne-Lise
Published: December 2015

This essay draws on the example of Emily Dickinson's experiments with meter and line to review the multiple valences that attach to precariousness, a term that is sometimes synonymous with précarité and the casualization of labor but that also carries a less negatively charged sense of flexibility, provisionality, and dependence on the morrow. It examines the irony whereby contemporary capitalism's reliance on stored energies not only has produced crises of insecurity unprecedented in scale but also threatens this other kind of precariousness, eliminating both the risk and the pleasure of proximate dependence.
Beckett and the Character of the Unchosen; Or, the Time of Precarity
Authors: Ty Michelle
Published: December 2015

Samuel Beckett's body of work is a literature committed or, more accurately, given over to nonsovereign states of being. Taking as a point of departure the prominence of choicelessness in Beckett's writing — along with the difficulties it introduces for character (which hardly develops), plot (that hardly accretes), and agency (which is hardly efficacious) — this essay examines how contemporary accounts of economic and affective precarity theorize the subject's (compromised) relationship to choice. Turning attention to the institution of the zero-hour contract and to Michel Foucault's analysis of “environmental” power, a form of intervention that he contrasts to the direct subjugation of individuals, this article suggests that neoliberalism manufactures prolonged states of precarity and choicelessness and does so, oddly, by creating conditions for the steroidal amplification of decision's renewal. This phenomenon, along with the curtailed temporalities that it engenders, is crystallized, though in a different register, in Beckett's 1981 play for television, Quad.
Accounting for Ashes
Authors: Adamson Morgan
Published: December 2015

This essay analyzes the aesthetics and politics of resistance in the work of Chilean artist Francisco Tapia (aka Papas Fritas) who burned $500 million worth of student debt promissory notes and presented them to the student movement as a work of art in May 2014. Analyzing the art of sabotage in the context of global struggles against debt under neoliberalism, this essay argues that Tapia's piece draws our attention to the politics of accounting and accountability in contemporary life while offering an alternative model based on solidarity.
How to make an oligodendrocyte
Authors: Goldman Steven A. , Kuypers Nicholas J.
Published: December 2015

Oligodendrocytes produce myelin, an insulating sheath required for the saltatory conduction of electrical impulses along axons. Oligodendrocyte loss results in demyelination, which leads to impaired neurological function in a broad array of diseases ranging from pediatric leukodystrophies and cerebral palsy, to multiple sclerosis and white matter stroke. Accordingly, replacing lost oligodendrocytes, whether by transplanting oligodendrocyte progenitor cells (OPCs) or by mobilizing endogenous progenitors, holds great promise as a therapeutic strategy for the diseases of central white matter. In this Primer, we describe the molecular events regulating oligodendrocyte development and how our understanding of this process has led to the establishment of methods for producing OPCs and oligodendrocytes from embryonic stem cells and induced pluripotent stem cells, as well as directly from somatic cells. In addition, we will discuss the safety of engrafted stem cell-derived OPCs, as well as approaches by which to modulate their differentiation and myelinogenesis in vivo following transplantation.
Role of epithelial sodium channels (ENaCs) in endothelial function
Authors: Guo Dongqing , Liang Shenghui , Wang Su , Tang Chengchun , Yao Bin , Wan Wenhui , Zhang Hailing , Jiang Hui , Ahmed Asif , Zhang Zhiren , Gu Yuchun
Published: December 2015

An increasing number of mechano-sensitive ion channels in endothelial cells (ECs) have been identified in response to blood flow and hydrostatic pressure. However, how these channels response to flow under different physiological and pathological conditions remains unknown. Our results showed that ENaCs were co-localized with hemeoxygenase-1 (HO-1) and hemeoxygenase-2 (HO-2) within the caveolae on the apical membrane of ECs and were sensitive to stretch pressure and shear stress. ENaCs kept low activities until their physiology environment was changed; in this case, the up-regulation of HO-1, which in turn facilitated heme degradation and hence increased the carbon monoxide (CO) generation. CO potently increased the bioactivity of ENaCs, releasing the channel from inhibition. Endothelial cells started to response to shear stress by increasing the Na+ influx rate. Elevation of [Na+]i hampered the transportation of L-arginine, resulting in impairing the nitric oxide (NO) generation. Our data suggested that ENaCs endogenous to human endothelial cells were mechano-sensitive. Persistent activation of ENaCs could inevitably lead to endothelium dysfunction and even vascular diseases such as atherosclerosis.
The importance of Lotmanian semiotics to sign theory and the cognitive neurosciences
Authors: Andrews Edna
Published: December 2015

The following paper is based on a presentation given as the Juri Lotman Lecture at the University of Tartu conference “Creative Continuity: 50 years of Sign Systems Studies”, on December 5th, 2014. The focus of the current analysis is to bring to light important new directions in cognitive neuroscience and cognitive neurolinguistics and how Lotman’s work contributes to deepening our understanding of the complex relationship of language(s) and brain(s) and the ever present dynamic cultural context.
Practice of using household service: foreign and domestic experience
Authors: Ермакова Елена , Ermakova Elena
Published: December 2015

The article is devoted to the peculiarities of functioning of the household service on the material of the

InterContinental Hotels Group (IHG) which is the largest international hotel chain by number of rooms; in

particular they examine the Holiday Inn Express Rolling Meadows, USA, and the hotel “ Vostok” located in

Tyumen, Russian Federation. They examine the standard of housekeeping, cleaning technology and the order

of service. The author characterizes timing parameters for the service and the number of personnel involved in

the service. They say about the service stages of rooms. The completeness of the house cleaner carts characterize

on the material of Holiday Inn Express Rolling Meadows. It can have: the cleaner, the laundry bag, trash bag,

broom, and dustpan, chemicals, funds for a complete bathroom, linen, towels, bathrobes, kitchenette, dry

cloth for cleaning bathrooms, sponge, brush, plunger, bucket, notepads and pens. They examine its movement

when cleaning room stock. The article proposes speech clichés and communicative strategies used by the house

cleaner while cleaning the rooms (in particular, the phrase on the plates’ clean rooms). The author makes

the conclusion that clean technologies in the hotel Vostok and the Holiday Inn, despite the absence of unified

standards, have many things in common. Even if there are differences in the process of cleaning (for example,

a cart in the hotel Vostok is less than in the Holiday Inn Express Rolling Meadows), they are based on rational

conditions (there are special rooms for maids in the hotel to fill the cart). Generally, the author notices the

importance of the house cleaner in the functioning of a household service, because the cleanliness of the room,

and thus profits of the hotel depends on this profession.
Services of mass media and personal ecology: issue history
Authors: Ефимова Людмила , Efimova Lyudmila
Published: December 2015

The media have a strong influence on public life in general, as well as on moral and socio-psychological image of every member of society in particular because any new information, broadcasted by media, directs in a certain way and contains repeated stereotypes of political orientations and values, self-reinforcing in the minds of individuals. Mass media has a powerful impact on the consciousness of every member of society, and is an effective influence on emotions of the individual, means of operative delivery of the selected information in different “territorial nooks” of any regions of the planet. The most demonstrative example is electronic media. Today, the impact of the media on the individual has increased much more. The Internet and television dominate other media in terms of impact; they have become the life of almost every family.
An essay on the history and hermeneutics of Naṣīḥat Al-mulūk by Ghazālī, Abu Hamid Muḥammad ibn Muḥammad Al-tūsī: hermeneutic code
Authors: Конурбаев Марклен , Konurbaev Marklen , Конурбаев Салават , Konurbaev Salavat
Published: December 2015

Abstract: A hermeneutic analysis of the Oriental Philosophers’ writings is invariably a matter of great challenge and difficulty. It is always full of allegory and literary divagations which intersperse a smooth flow of argumentation. This paper is written by Marklen Konurbaev, Professor of Literature at Moscow State University and his son Salavat, a student of Arabic Philosophy. The paper consists of six parts and attempts to reveal the hidden message of a famous extract from the renowned book Ihya Ulum Al Din by a Persian philosopher Ghazālī, Abu Ḥamid Muḥammad Ibn Muḥammad Al-Tūsī, devoted to the analysis of the notion of “fairness” in the doings of a ruler. The hermeneutic analysis was performed based on the methodology propounded by Roland Gérard Barthes — a French literary theorist, philosopher, linguist and critic. This is the first ever attempt to put together the methodological efforts of a Western scholar and profoundly oriental piece of philosophy. Results of the hermeneutic study are stunning and elucidating. The paper could be recommended to the students of literature and philosophy at the universities and colleges.
Family and property demographics of landowner peasants in Russia in the middle of the eighteenth century
Authors: Прохоров Михаил , Prokhorov Mikhail
Published: December 2015

The article provides an analysis of family and property demographics of the peasant household in the fortress

village of Russia in the middle of the eighteenth century. The author that the development of the topic is not

enough in the historical literature. The source base of this study was documents extracted mainly from the

funds of the personal origin: orders and instructions of the landlords, reports and records of governing estates.

The census records and homestead descriptions of villages are especially valuable as they provide the list of

names of the inhabitants of the yard, their age, family relationships. The object of study was the large and

medium landowners ‘ ownership of the Central provinces of Russia – Moscow, Suzdal and Rostov, where there

was an early process of formation of local-patrimonial estates. Based on the system approach such tasks as the

population of the yard, the composition, structure and typology of family, its human resources, system of marriage

are examined. The article presents the demographic characteristics of the family with children, adolescents,

healthy and elderly people. The age and sex ratio of male and female population of a peasant family are

also studied. In the work there was discussed such question which is little-studied in Russian historiography as

marital relations in land environment: the proportion of married couples, the age of those who enter into marriage,

age difference between husband and wife. Special emphasis is given to the impact of the financial status

of the yard to the marital status of the peasants. Negative aspects of the demographic policy of the landowners,

which were directed on the increase, first, the solvency of the rural world, were clarified. The obtained results

will be useful for developing an information base of research on Russian history and historical demography.
Every pound spent has a positive impact
Authors: Tanuku Purnima , Gibbin Fay
Published: December 2015

MA Education Ltd, St Jude's Church, Dulwich Road, London, SE24 0PB. neil.henty@markallengroup.com
A premium on language
Authors: Parlane Kerry
Published: December 2015

In a follow-up to her workshop at the EY2015 conference, Kerry Parlane explores how Early Years Pupil Premium can be used to improve early communication and language skills for disadvantaged children.
Children's big questions
Authors: Sabine Alex
Published: December 2015

Children are subject to a vast range of experiences, most of which are not easily articulated to adults, so we should not be surprised when they express philosophical thoughts, such as ‘why are we here’?
Quality of assessment
Authors: Bamforth Heather , Kirkup Catherine
Published: December 2015

What makes a good Early Years Standardised Assessment now that the government has pushed to reintroduce baselines at the start of reception year? There are three key factors in all good systems.
Developing communication
Authors: Baston-Pitt Linda
Published: December 2015

The senior management team of any setting will drive the staff culture, but successfully conveying or sharing ideas and feelings to a group of other people is one of the biggest challenges a leader will face.
Following instructions
Authors: Brown Paula
Published: December 2015

Children younger than five-years-old receive a substantial number of instructions every day, but here we look at where instructing is appropriate and where it is not, and how to do this most effectively.
On Her Majesty's (not so) Secret Service
Authors: Harris Sean
Published: December 2015

Inspired by the release of the latest James Bond film, Sean Harris discusses the 007-themed principles that have driven his work to close the attainment gap and deliver effective Pupil Premium outcomes
Improntas vegetales en arquitectura e improntas de cestería en el yacimiento ibérico del Cerro de la Cruz (Almedinilla, Córdoba)
Authors: Moralejo Ordax Javier , Kavanagh de Prado Eduardo , Quesada Sanz Fernando
Published: December 2015

Este trabajo presenta un amplio conjunto inédito de elementos asociados a la arquitectura doméstica y a partir de ello arroja nueva luz sobre las técnicas constructivas ibéricas en Andalucía, sobre las que apenas hay detallados publicados. Se analizan en detalle las improntas de elementos arquitectónicos vegetales sobre bloques de barro, que a su vez formaron parte de esa misma arquitectura, así como las improntas de elementos de cestería. Todo procede de las recientes excavaciones en el poblado ibérico del Cerro de la Cruz (Almedinilla, Córdoba), destruido a mediados del s. II a.C. Se relacionan estos elementos con otros similares ya conocidos.
Un santuario urbano hallado en Contributa Iulia (Medina de las Torres, Badajoz)
Authors: Mateos Cruz Pedro , Pizzo Antonio
Published: December 2015

Este artículo presenta el hallazgo de un santuario urbano en la ciudad de Contributa Iulia. Gracias a la utilización de un conjunto de técnicas no destructivas relacionadas con la fotografía aérea, la geofísica y reconocimiento de superficie se ha documentado un nuevo complejo arquitectónico. Tras su excavación arqueológica, se ha podido relacionar con un espacio cultual presidido por un templo tetrástilo ubicado en la zona central de un recinto situado cercano a una de las puertas principales de acceso a la ciudad. Junto al templo se documenta un pozo en el que apareció un ara votiva realizada en granito dedicada a las divinidades Fontano y Fontilis.
Un trapezoforo con Eracle e un’erma bifronte con Eracle e Silvano da Verona
Authors: Quattrocchi Luigi
Published: December 2015

Il presente articolo vuole portare alla conoscenza degli studiosi due sculture marmoree poco note: un trapezoforo con erma di Eracle e una doppia erma con Eracle e Silvano. Dopo uno studio sulle statue in questione si arriva a capire se effettivamente, attraverso altre fonti come le epigrafi, nel territorio del veronese e dunque nella Cisalpina, ci fossero attestazioni di culti per Eracle e Silvano.
Physical and constraint DOF reduction of redundant multibody systems using the Proper Orthogonal Decomposition
Authors: Stadlmayr Daniel , Witteveen Wolfgang , Steiner Wolfgang
Published: December 2015

Multibody simulation software has entered the industrial user's market several years ago and is nowadays part of a CAE engineer's everyday life. Due to usability and time advantages in the modeling process, such a simulation software is typically based on modeling strategies using a redundant set of coordinates. Although such a redundant set simplifies the modeling process, modeling without a minimal set of coordinates forces the multibody dynamics into differential algebraic equations (DAEs). Unnecessary degrees of freedom (DOFs) are introduced easily through kinematic relations and especially when talking about planar problems, modeled in a 3D space, the number of unnecessary DOFs increases rapidly. Further, unnecessary constraint equations which address such kinematic chains or unstressed DOFs are typically introduced. The d-index three DAE systems of second order considered in this contribution are modeled in the freeware multibody simulation software FreeDyn using Euler parameters and solved in the open source software Scilab, applying a HHT solver algorithm. Due to the characteristic nonlinear system matrices, model reduction is not possible a-priori but needs at least one full system forward simulation to rest on. Inspired by repetitive simulations necessary for e.g. parameter identification, we focus on reducing such a highly redundant set of coordinates close to a minimal set of coordinates representation by eliminating both, physical and constraint DOFs. This contribution first gives a brief introduction to the underlying DAE system. In the second part model reduction of redundant physical DOFs using a modied linear Galerkin projection based on a velocity level Proper Orthogonal Decomposition (POD) is proposed. The subspace found by POD is further applied to identify unneeded constraint equations related to a.) - constraints addressing unneeded physical DOFs and b.) constraints which are orthogonal to the found subspace and, hence, satisfied by the projection matrix. The method is illustrated using a simple analytical example and further applied to a rigid V8 crankdrive consisting of 119 DOFs as well as 118 constraint equations. In the conclusion the proposed methods are discussed and an outlook to parameter identification, using a reduced adjoint system, and therewith arising special needs to the underlying subspace is given.
Loop Quantum Gravity meets Topological Phases of Matter at the Black Hole horizon
Authors: Pithis Andreas G. A. , Ruiz Euler Hans-Christian
Published: December 2015

In this work we investigate the role played by large diffeomorphisms of quantum isolated horizons for the statistics of Loop Quantum Gravity black holes by means of their relation to the braid group. The
mutual exchange of quantum entities in two dimensions is achieved by the braid group, rendering the statistics anyonic. With this we argue that the quantum isolated horizon model of LQG based on
SU(2)_k-Chern-Simons theory explicitly exhibits non-abelian anyonic statistics, since the quantum gravitational degrees of freedom of the horizon can be seen as flux-charge composites. In this way a connection
to the theory behind the fractional quantum Hall effect and that of topological quantum computation is established, where non-abelian anyons play a significant role.
DEFECTS AND FAILURES OF JOINTS OF HISTORIC ROOF TRUSSES AND POSSIBILITIES OF USING FRP MATERIALS IN THEIR REHABILITATION AND STABILIZATION
Authors: Čejka Tomáš , Kroftová Klára , Šmidtová Markéta , Zigler Radek
Published: December 2015

The survey of selected historic roof trusses performed within the NAKIDF12P01OVV037project revealed numerous failures and defects of joints of roof truss elements ofhistoric and listed buildings. Based on the results of the survey, the article outlines potentialrehabilitation and reinforcement techniques of joints of roof truss elements in which the mostfrequent defects and failures were found using composite fabrics based on high-strength carbonfibres and epoxy resin (CFRP).
Tierras públicas y privadas para la cría de ganados y cultivos de café en una zona de frontera del Caribe colombiano: Valledupar (Magdalena), 1920-1940
Authors: Sánchez Mejía Hugues Rafael , Santos Delgado Adriana , Blanquiceth Miguel
Published: December 2015

En este artículo analizaremos la forma como se dio un proceso de expansión de la frontera agropecuaria en una subregión del Caribe colombiano, la provincia de Valledupar. Mostramos como un tipo de demanda del mercado, específicamente de productos como la carne y el café, propiciaron un movimiento y demanda de terrenos para el establecimiento de hatos o fincas agrícolas. Esta expansión se apoyó en una frontera donde la tierra era un bien abundante y relativamente barata. Así, encontramos que en menos de una década se da un mercado de tierras y transformaciones en el paisaje rural, desde la división de propiedades antiguas o indivisas, hasta la apropiación de terrenos estatales o baldíos para establecer en ellos potreros para la cría de ganados o siembra de café y otros productos agrícolas.
Arqueología en la capital de la Gran Colombia: Villa del Rosario, un ejemplo de reinvención de un glorioso pasado
Authors: Martín Juan Guillermo , Quiroz Raquel Sofía
Published: December 2015

Hacia finales del siglo XVIII se fundó la Villa del Rosario. Esta pequeña población, ubicada en la actual frontera entre Colombia y Venezuela, adquirió especial relevancia en el siglo XIX cuando en su iglesia se instaló el Congreso de 1821. Es en este congreso cuando se designa a Villa del Rosario como capital de la naciente república, conocida en la historiografía como la Gran Colombia. De este evento histórico surge la estructura jurídica de la nueva república, a través de su Carta Fundamental, convirtiéndose también en escenario del proceso independentista. Sin embargo, un terremoto, a finales del siglo XIX, destruyó la población y obligó su traslado. A principios del siglo XX, la búsqueda por reivindicar ese pasado glorioso, llevó a la reconstrucción de la sede del Congreso de 1821: el Templo Histórico. Las exploraciones arqueológicas realizadas en 2013, dan cuenta de un pasado distinto, quizás menos ostentoso, de lo que el saber popular había construido en los últimos cien años.
Oro negro del Caribe sobre la blanca bahía. El transporte naval de petróleo y el camino al autoabastecimiento en el puerto de Bahía Blanca, Argentina (1951-1963)
Authors: Mateo Oviedo José Antonio
Published: December 2015

El petróleo ha sido un tema de discusión política y económica que atravesó en todo el último siglo en la Argentina tanto a vertientes ideológicas como a intereses económicos. Como bandera, desde izquierda a derecha abundaron argumentos nacionalistas o antiimperialistas que se enfrentaron a otros aperturistas e internacionalistas. Como insumo, fue muchas veces el talón de Aquiles de los proyectos de desarrollo donde los cárteles petroleros pendulaban entre abastecerlo o extraerlo con fuertes concesiones. Al ser Argentina un país con petróleo, la producción nacional y la importación se combinaron con distintas proporciones según lo que podía producir la empresa nacional o lo que podía importarse según los recursos disponibles. Un aspecto de esta problemática sin embargo no ha sido tratado y responde a una serie de interrogantes tales cómo ¿Cuál fue la progresión del ingreso de petróleo en Bahía Blanca en relación al total del país? y ¿Cómo se refleja la tendencia al autoabastecimiento en ambos niveles de integración? ¿Dónde se producía el petróleo importado? ¿Cómo se transportaba? ¿Quiénes lo transportaban? Y finalmente ¿Cómo impactó la política petrolera en la navegación?, es decir ¿Cómo impactó en la navegación la importación y los contratos petroleros en la distribución de petróleo entre los lugares de producción, refinamiento y consumo? A partir de los datos aportados fundamentalmente por los libros de la Aduana de Bahía Blanca, intentaremos responder a estas y otras pregunta
Lack of Association between Interleukin-18 –607 C/A Gene Polymorphism and Pulmonary Tuberculosis in Zahedan, Southeast Iran
Authors: Taheri M. , Hashemi-Shahri S. M. , Hamzehnejadi M. , Naderi M. , Moazeni-Roodi A. , Bahari G. , Hashemi Mohammad
Published: December 2015

Interleukin-18 (IL-18) plays a critical role in immune response, contributing to the pathogenesis and pathophysiology of infectious diseases. Polymorphisms in the IL-18 genes are known to influence expression levels and may be associated with outcome of infections. The objective of this study was to determine whether the presence of IL-18 polymorphisms –607 A/C (rs1946518) was associated with tuberculosis disease. We investigated the functional polymorphism of IL-18 (rs1946518) in 174 patients with pulmonary tuberculosis (PTB) and 177 healthy subjects. Genotype analysis was done using tetra amplification refractory mutation system-PCR (T-ARMS-PCR). The allelic and genotypic frequencies of the IL-18 polymorphism did not differ significantly between PTB and the controls. Our finding suggests that IL-18 polymorphism (rs1946518) may not be a risk factor for susceptibility to tuberculosis in a sample of Iranian population. Further studies are required to validate our findings.