bluuebunny/crossref_metadata_2025 huggingface dataset:
„Agiles Leadership” - Zur agilen Führungskraft geboren?
Authors: Meindl Stefanie , Pfähler Julia , Bissel Moritz
Published: May 2021

Um flexibel, agil und innovativ am Markt agieren zu können, benötigen Unternehmen Mitarbeiter, die ihrem Beruf gern und mit viel Leidenschaft nachgehen. Daher suchen sie nach Persönlichkeiten, die in ihrem Innersten Gestalter, Macher und Unternehmer sind und zugleich verantwortungsvoll handeln. Aufgabe von Führungskräften ist es, ein vertrauensvolles Arbeitsumfeld zu schaffen, in dem Mitarbeiter Bestleistungen geben können, wollen und dürfen. Ein derartiges Arbeitsumfeld zieht nicht nur junge motivierte Talente magisch an, sondern wirkt sich auch direkt positiv auf die Kundenzufriedenheit, die Flexibilität und die Innovationskraft aus und ist somit ein Schlüsselfaktor für nachhaltigen Unternehmenserfolg!
Entwicklung eines Konzepts für ein dynamisches Risikomanagement bei Entwicklungsprojekten
Authors: Ghadiri Daniel , Schlücker Eberhard
Published: May 2021

Ziel ist es, ein Konzept für das Risikomanagement mit dem Fokus Entwicklungsprojekte / Innovationsprojekte zu entwickeln. Da die Ziele dieser Projekte auf verschiedenen Szenarien basieren und sich ständig ändern können, sollte man ein dynamisches Risikomanagement durchführen. Bei diesem Artikel wird ein Konzept für ein dynamisches Risikomanagement entwickelt, bei dem die dynamischen Aspekte des Risikomanagements erforscht werden. Darauf aufbauend wird eine Methode für die Berechnung der Gesamtprojektrisiko-Zahl vorgestellt, um das Gesamtprojektrisiko während des Projektlebenszyklus dynamisch monitoren und steuern zu können.
VACCINATION OF CHILDREN WITH MALIGNANT DISEASES: THE URGENCY OF THE PROBLEM
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Deordieva E.A.
Published: May 2021

Currently, the number of cases of malignant diseases in children is increasing, but the number of children who have recovered is also increasing. In the past few years, the number of deaths has decreased thanks to the latest technologies for treating cancer patients, but there are still a number of problems in the lives of small patients after treatment. One of the important problems is the lack of continuation of the mandatory vaccination of children who have undergone a malignant disease, according to age and in accordance with the national calendar, despite the availability of clinical guidelines in domestic and foreign publications on preventive vaccination of this cohort. Many physicians make unjustified medical exclusions from vaccination based only on their own biases, which can be justified by the limited number of publications on this topic. In turn, vaccination can reduce the number of deaths from infectious complications and provide hope for further full life. Children with malignant diseases should be vaccinated against infectious diseases that can be prevented with vaccines after completion and sometimes during treatment. For such patients, there should be a vaccination schedule that takes into account the available therapy that may lead to the suppression of immunity. This article is devoted to the vaccination of children with malignant diseases.
INITIAL EXPERIENCE IN ESTIMATING TUMOR MUTATION BURDEN IN PEDIATRIC HEPATOCELLULAR CARCINOMA
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Akhaladze D.G. , Rabaev G.S. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Zhukov N.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Pyatnitskiy M.A. ,   ONCOGENOTEST, LLC, Moscow, Russia,   Institute of Biomedical Chemistry, Moscow, Russia, Gorochov N.S. ,   ONCOGENOTEST, LLC, Moscow, Russia, Zhulikov Y.A. ,   ONCOGENOTEST, LLC, Moscow, Russia,   N.N. Blokhin Russian Cancer Research Centre, Moscow, Russia, Rabaev G.G. ,   ONCOGENOTEST, LLC, Moscow, Russia, Kasatskiy A.A. ,   ONCOGENOTEST, LLC, Moscow, Russia, Volodin I.V. ,   Academician N.P. Bochkov Research Centre of Medical Genetics (RCMG) of the Russian Academy of Sciences, Moscow, Russia, Myakova N.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: May 2021

The level of tumor mutation burden (TMB) is a predictive factor of immune checkpoints that determines the potential effectiveness of immune checkpoint inhibitors and indications for their prescription regardless of the type of tumor in adults and children. However, the prevalence of tumors with high TMB in the pediatric population has not been well studied. Objective of the research: to assess the detection frequency of high TMB (>10 mutations per megabase) in pediatric hepatocellular carcinoma (HCC). Materials and methods of research: Next Generation Sequencing, Ion AmpliSeq™ Comprehensive Cancer Panel (409 genes) of tumor DNA samples from 4 children with HCC was performed. The calculation of the mutational load was carried out according to the work of Z.R. Chalmers et al. Results: out of 4 analyzed samples, TMB levels have lower cut-off value than needed for the immunity checkpoint inhibitors for 2 patients to administer: 5,9 mut/MB (primary tumor), 9,2 mut/MB (metastasis), while in 2 other patients the TMB has level above the threshold – 10,9 mut/MB (primary tumor) and 48,5 mut/MB (relapse metastasis), respectively. Conclusion: this paper presents the initial experience of estimation of the TMB level in children with HCC. In our case series report, the level allowing the prescription of immunotherapy (>10 mut/MB) was observed in 2 patients. Further research on a larger cohort of patients is useful to assess the role of mutational burden in disease prediction and effectiveness of immunotherapy.
STAGED SURGERY TREATMENT OF TETRALOGY OF FALLOT AND HEPATOBLASTOMA IN A CHILD
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Akhaladze D.G. , Shatalov K.V. ,   A.N. Bakulev Scientific Center for Cardiovascular Surgery, Moscow, Russia, Arnautova I.V. ,   A.N. Bakulev Scientific Center for Cardiovascular Surgery, Moscow, Russia, Kachanov D.Y. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Rabaev G.S. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Akhtiamov R.R. ,   A.N. Bakulev Scientific Center for Cardiovascular Surgery, Moscow, Russia, Utalieva D.T. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Myakova N.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: May 2021

In order to achieve good long-term results of combination treatment in children with malignant neoplasms, continuity of stages of the therapy and adherence to the time intervals between the stages are necessary. Severe accompanying pathology can make it difficult or impossible to complete all the necessary steps. The presented clinical case of a child with hepatoblastoma and Tetralogy of Fallot demonstrates the importance of the interdisciplinary work of oncologists, surgical oncologists and cardiac surgeons to ensure the optimal treatment algorithm for such patients.
PRIMARY HYPOTHYROIDISM IN A HIGH-RISK NEUROBLASTOMA PATIENT AFTER 131I-MIBG THERAPY: A CLINICAL CASE REPORT AND LITERATURE REVIEW
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Utalieva D.T. , Babakhanova S.B. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Ilyina E.Yu. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Andreeva N.A. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Likar Yu.N. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Shcherbakov A.P. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Kachanov D.Yu. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Shamanskaya T.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: May 2021

In recent decades, there has been marked progress in understanding the biology of the most common extracranial solid tumor of childhood – neuroblastoma (NB), which led to a significant improvement in treatment outcomes due to stratification of patients into risk groups, intensification of treatment of patients with metastatic disease and the presence of unfavorable molecular genetic markers. Survivors who have received multimodal therapies, including chemotherapy, high-dose therapy and autologous peripheral stem-cell transplantation, 131I-metaiodobenzylguanidine (131I-MIBG) therapy, radiation therapy, and immunotherapy have a high risk of developing long-term side effects of treatment (LT SE). The study of the nature and frequency of LT SE after completion of therapy in patients with NB is important to ensure the quality of life and minimize severe health disorders. This article presents a literature review and description of a clinical case report of primary hypothyroidism in a high-risk patient with NB who received multicomponent treatment, including 131I-metaiodobenzylguanidine therapy due to the persistence of MIBG-positive foci after the induction chemotherapy.
DIAGNOSTICS AND ENZYME REPLACEMENT THERAPY OF CHILDHOOD-ONSET HYPOPHOSPHATASIA IN A 5-YEAR-OLD BOY
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Soboleva M.K. , Maslova E.A. ,   Novosibirsk Oblast Regional Clinical Diagnostic Center, Novosibirsk, Russia
Published: May 2021

The article presents a clinical case report of hypophosphatasia, a rare congenital genetically determined disease diagnosed in a boy at the age of 3 years and 6 months. The diagnostic search took more than 2 years before the correct diagnosis was made, which is explained by the rarity of the disease and the lack of doctors awareness about it. The pathology was suspected on the basis of a combination of clinical evidence and characteristic complaints (early loss of primary teeth with an unchanged root, rickets-like skeletal deformities, motility disorders) in combination with a pathologically low level of alkaline phosphatase. The detection of mutations characteristic of the disease in the ALPL gene in the boy, his mother and father made it possible to finally confirm the diagnosis. The patient received a 7-month course of enzyme replacement therapy with Asfotase alfa, which significantly slowed down the progression of the disease and was not accompanied by the development of side effects. A feature of the patient's disease is the involvement of the urinary system in the pathological process, which is manifested by hypercalciuria, nephrocalcinosis and decreased renal function.
The concept and signs of public control of power in the Russian Federation, as well as its relationship with other forms of control of power
Authors: Goncharov Vitaly Viktorovich
Published: May 2021

This article is devoted to the constitutional and legal analysis of the concept and signs of public control of power, as well as its relationship with other forms of control of power. We affirm that the analysis of the concept of “public control of power” in constitutional law, the study of its features and its place in the system of other forms of control of power, will allow us to identify specific priorities for ensuring the exercise of the right of citizens of the Russian Federation to exercise public control.
Modelling universal design for learning to faculty as learners developing engaging educators
Authors:   , Clyne Carolee
Published: May 2021

The question explored through this research study is: Does modelling Universal Design for Learning to university faculty as learners deepen their engagement as educators? Through providing training where faculty themselves are learning about Universal Design for Learning (UDL) through a UDL modelled environment (CAST, 2018b; Meyer, Rose, & Gordon, 2014), this research project investigates if this experience translates into a stronger role as educators for these faculty. Participants in this research project are faculty members teaching in disciplines associated with Natural Resources and Environmental Studies. Through a virtual World Café, participants of the workshop shared their reflections and experiences as they learned about learning. Using the UDL framework’s horizontal organization, as conceptualized by CAST, as a lens, participant reflections were themed to determine their progression towards learning and understanding the UDL framework in this context. Evaluation of this research data indicated that faculty in this study are located along UDL Access and Build rows of the UDL Guidelines reflecting a novice learning stage where greater cognitive energy is required (Posey, 2019a, 2019b). This knowledge provides evidence that professional development opportunities should support strategies and provide the guidance necessary to foster their skills towards the UDL goal of becoming an expert learner. Elevating faculty to the UDL expert teacher level in this context enhances their skills and understanding in their creation of inclusive learning environments for their classrooms (Meyer, Rose, & Gordon, 2014).
La televisión como herramienta para la integración social: narraciones y experiencias de migrantes asiáticos en la ciudad de Mesina (Italia)
Authors: Olmos Alcaraz Antonia , Cava Gaetana
Published: May 2021

The paper analyses the use and consumption that a sample of Asian migrants living in Italy make of television, with the aim of knowing the potential of this media as a tool for social integration. For this, we have worked through a semi-structured interview, applied to 60 people from China, the Philippines and Sri Lanka, resident in the city of Messina. The results of the research indicate that the people participating in the study take advantage of certain contents and formats provided by television to reinforce language learning and knowledge of Italian society (essential elements within integration processes). We therefore conclude that television has the potential to be a good resource for social integration, without this obviating the need not to carry out simplistic and superficial analysis that ignore the multidimensional and multidirectional nature of the process of the integration.
Pengujian Air Sulingan Kulit Buah Kopi dengan Metode Destilasi Air dan Efeknya sebagai Atraktan Penggerek Buah Kopi (Hypothenemus hampei Ferr.) (Curculionidae:Scolytiidae)
Authors: Suwantapura Siska Rasiska , Darmawan Jemia Afdhila , Yulia Endah
Published: May 2021

Penggerek buah kopi/PBKo (Hypothenemus hampei Ferr.) adalah hama utama pada tanaman kopi Arabika yang dapat menyebabkan kerusakan hingga mencapai 40%. Pemanfaatan kulit buah kopi sebagai atraktan PBKo diduga dapat menjadi salah satu cara pengendalian PBKo dengan cara memengaruhi perilakunya. Salah satu metode isolasi senyawa sumber atraktan dari bahan tanaman adalah metode destilasi baik itu destilasi air maupun destilasi air dan uap. Penelitian ini bertujuan untuk mengetahui komposisi fitokimia kulit buah kopi dengan metode isolasi destilasi air dan efeknya terhadap ketertarikan hama betina PBKo. Percobaan dilaksanakan pada bulan November 2019 hingga Maret 2020 di Laboratorium Pestisida dan Toksikologi Lingkungan, Departemen Hama dan Penyakit Tumbuhan, Fakultas Pertanian, Universitas Padjadjaran. Rancangan Acak Lengkap digunakan dengan tujuh perlakuan yang terdiri dari kontrol air sulingan kulit buah kopi sehat 4 ml, 8 ml dan 12 ml, serta air sulingan kulit buah kopi sakit 4 ml, 8 ml dan 12 ml. Masing-masing perlakuan diulang sebanyak empat kali. Hasil penelitian menunjukkan bahwa air sulingan kulit buah kopi sehat mengandung alkaloid dan saponin, sedangkan air sulingan kulit buah kopi terinfestasi PBKo mengandung alkaloid, triterpenoid dan steroid. Efeknya, hama betina PBKo tidak memiliki ketertarikan terhadap air sulingan kulit buah kopi dengan metode destilasi air.
THE GROWTH, PHOTOSYNTHETIC PARAMETERS AND NITROGEN STATUS OF BASIL, CORIANDER AND OREGANO GROWN UNDER DIFFERENT LED LIGHT SPECTRA
Authors: Matysiak Bożena , Kowalski Artur
Published: May 2021

Growth, morphological parameters, photosynthetic performance and nitrogen status were investigated in leafy herbs grown in light-limited time in a greenhouse under different light spectra emitted by LEDs. Fluorescence-based sensors that detect crop N status and maximum photochemical efficiency of photosystem II were used in this study. Four light treatments with the ratio of Red, Blue and White LEDs including 1) R40 + B50 + W10, 2) R70 + B20 + W10, 3) R70 + B20 + W10 + Far-Red and 4) White LEDs as control were used in this study. Dominant red light and/or white LED lights at 200 µmol m–2 s–1 at plant level and a 12 h photoperiod provided the most favourable conditions for plant growth and development compared to a high proportion of blue light (R40 + B50 + W10). However, plants grown under a high proportion of blue light had a higher chlorophyll index and nitrogen balance index (NBI) than under dominant red light treatments. Our study indicates the significant potential of fluorescence-based sensors in photobiology research as well as in the production of leafy herbs under LED lights.
Predictors of adherence to composite therapy after acute coronary syndromes
Authors: Stabile Eugenio , Franzese Michele , Chianese Salvatore , Alfani Arturo , Gerardi Donato , Colaiori Iginio , Annunziata Monica , Nappi Pierluigi , Scalise Martina , Di Serafino Luigi , Puzone Brunella , Avvedimento Marisa , Leone Attilio , Ilardi Federica , Piccolo Raffaele , Franzone Anna , Cirillo Plinio , Morisco Carmine , Trimarco Bruno , Esposito Giovanni
Published: May 2021

Aims

Adherence to medical therapy following acute coronary syndrome (ACS) affects a patient's prognosis. In this cohort study, we sought to assess the factors that could affect a patient's adherence to therapy after ACS.

Methods

We prospectively collected information from patients (N = 964) hospitalized at the coronary care unit of the Federico II University Hospital, from 1 January 2015 to 30 June 2017, for ACS. Adherence to three classes of drugs including statins, antiplatelets [dual or single antiplatelet agent (SAPT)] and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACE-I/ARB) and their composites were assessed at 1 month, 1 and 2 years after discharge.

Results

At 30 days adherence to prescribed therapy was 94.4% for dual antiplatelet therapy (DAPT), 78.2% for statins, 92.7% for ACE-I/ARB and 70.7% for multitherapy. At 1 year, it was 91.1% for DAPT, 81.2% for ACE-I/ARB, 84.9% for statins and 71.4% for multitherapy. At 2 years, it was 97.1% for SAPT, 78.1% for ACE-I/ARB, 91.8% for statins, 72.8% for multitherapy. Multivariable logistic analysis demonstrated that at each time point, a telephone follow-up assessment predicts nonadherence to multitherapy and that a percutaneous coronary intervention at the index hospitalization is an independent predictor of adherence to composite therapy at 1 month and 1 year.

Conclusion

Up to 2 years after ACS, three out of four patients are adherent to multitherapy prescription; percutaneous coronary intervention during the index hospitalization improves a patient's adherence, whereas telephone follow-up is associated with reduced adherence to multitherapy.

Campania Salute Network Registry (Clinical Trials.gov Identifier: NCT02211365).
Administrative Functions of Implementation, Control of Administrative Decisions, and Protection of Rights
Authors: Perlingeiro Ricardo
Published: May 2021

This essay includes a comparative analysis of the traditions of administrative law in Latin American and their impact on the contemporary scene and trends in the general orientations of its administrative justice systems. This analysis is limited to Latin American countries of Iberian origin under the jurisdiction of the Inter-American Court of Human Rights (“I/A Court H.R”). The method followed by the author is to point out the roles attributable to the administrative authorities and to attempt to identify a distinction in Latin America between the “administrative function of implementation”, “control of the legality of administrative decisions” (unrelated to any adjudicative function) and the “protection of rights” (by means of an adjudicative function) while examining their historical genesis and possible future trends. From that perspective, the text discusses certain administrative powers, such as disciplinary or other regulatory powers, and their forms of concrete application; the prerogatives and instruments of the authorities and of their decision-making employees in the exercise of the functions of implementation; the control of administrative decisions by those authorities themselves and by external bodies; and judicial and extrajudicial protection of rights against administrative decisions. The author concludes that Latin American administrative law, despite the fact that its civil-law substantive roots have always coexisted with judicial review typical of common law, is currently tending, on the one hand, to approximate the U.S. model of administrative adjudication and, on the other, to adapt to I/A Court H.R case law with respect to the administrative function of implementation in harmony with the fundamental right to good administration which, combined with a critical re-examination of diffuse control of the legality of administrative rules in court, would safeguard the true role of adjudicating bodies (administrative authorities or courts) in their function of protecting individual rights for the sake of more fair and equitable administrative justice.
Contamination of bottom sediments by lead, zinc and cadmium in Rzeszow reservoir
Authors: Maj-Zajezierska Katarzyna , Koszelnik Piotr
Published: May 2021

The aim of the present study was to determine the level of contamination of the bottom sediments in the Rzeszow reservoir by the selected heavy metals Pb, Cd and Zn, and to identify the potential environmental risks of heavy metals content basing on available assessments and classification of bottom sediments. The Rzeszow reservoir is situated on the Wisłok River in the Podkarpackie Voivodeship, southeaster Poland, was constructed on 1974. Nowadays, as a result of silting, the reservoir reduced its surface and depth, which does not have a positive effect on the assumed functions it is to perform. The study was conducted in 2016. The samples of sediment were collected in five locations. Samples were taken twice: in June and in October. The following concentrations have been determined: cadmium - 0.01 ÷ 0.92 mg•kg–1, zinc - 54.39 ÷ 128 mg•kg–1, lead - 2.98 ÷ 25.42 mg•kg–1. The decline trend in the sediment is following: Zn > Pb > Cd. For the assessment of sediment contamination, following methods: aquatic sediment quality classification used by the Polish Geological Institute - I class, Regulation of the Minister of Environment of April 16 2002 on the types and concentrations of substances contaminating the excavated material – unpolluted and LAW sediment classification – Pb - I/I-II, Cd - I/I-II/II and Zn - I/I-II. The obtained results were compared with the results obtained by the other authors in earlier years, which led to the estimated changes in the concentration of the tested metals.
Legal aspects of the resolutions determining the acceptable types and quality of fuels under Polish legislation
Authors: Makuch Kinga
Published: May 2021

The article focuses on the selected aspects of introducing a resolution by a self-government of a province, which allows to determine the acceptable types and quality of fuels. The impact of polluted air on human health is significant. The actions carried out by the local authorities should be aimed on seeking effective air protection remedies; nonetheless, the scale of these activities seems to be still insignificant. One of the legal mechanisms is introducing resolutions determining the acceptable types and quality of fuels by a self-government of a province in order to protect the health of Polish residents and reduce the negative impact of air pollution on the environment. The question, however, is whether such resolutions could be audited with respect to the execution of such a resolution and whether they effectively lead to air quality improvement.
UTICAJ ORGANIZACIONE KULTURE NA USPEŠNOST PREVAZILAŽENJA KRIZNE SITUACIJE - PANDEMIJE VIRUSA COVID-19
Authors: Dulić Dajana
Published: May 2021

U ovom radu, objašnjene su teorijske postavke organizacione kulture i njenih stilova. Takođe je prikazan pregled literature na temu krize i kriznog menadžmenta, sa posebnim osvrtom na aktuelnu situaciju – pandemiju virusa COVID-19. Predstavljeni su i načini na koje se organizacije suočavaju sa pandemijom. U praktičnom delu rada su, na osnovu empirijskog istraživanja, identifikovani uticaji koje organizaciona kultura ostvaruje na uspešnost prevazilaženja krizne situacije.
МОТИВАТОРИ И ДЕМОТИВАТОРИ У ПОСЛОВАЊУ СРЕДЊИХ ПРЕДУЗЕЋА
Authors: Совиљ Симона
Published: May 2021

Како би компаније данас опстале и могле да се развијају у овом изразито турбулентном окружењу, поред велике конкуренције, морају истовремено да постижу високу учинковитост на разним пољима пословања. Један од главних извора конкурентске предности модерних и успешних организација састоји се у правилној комуникацији и мотивацији запослених. Комуникација је неопходна за успостављање и спровођење циљева предузећа, развој планова за њихово остварење, организовање људских и других ресурса на најуспешнији и најделотворнији начин, затим за избор, развој и оцењивање чланова организације, као и за вођење, усмеравање, мотивисање и креирање климе у којој су људи вољни да доприносе циљевима.
ANALIZA RAZVIJENOSTI TRŽIŠTA OSIGURANJA U REPUBLICI SRBIJI SA POSEBNIM OSVRTOM NA OSIGURANJE OD ODGOVORNOSTI
Authors: Antonić Momčilo
Published: May 2021

U ovom radu su prikazane teorijske i metodološke osnove osiguranja, a sa posebnim osvrtom na osiguranje od odgovornosti. Pored toga, predstavljene su i osnovne podele osiguranja i osnovni pojmovi značajni u osiguranju. Predstavljena je analiza razvijenosti tržišta osiguranja u Republici Srbiji sa osvrtom na osiguranje od odgovornosti. Data je komparativna analiza sa tržištem osiguranja u razvijenim zemljama.
UNAPREĐENJE PROCESA SKLADIŠTENJA U KOMPANIJI „SUNOKO“
Authors: Ačanski Vesna
Published: May 2021

Na samom početku rada dat je teorijski prilaz na temu logistike a nakon toga  prikazan je značaj procesa skladištenja kao logističke funkcije. Svrha ovog rada jeste rešavanje problema nedovoljnog kapaciteta skladišta na način koji obezbeđuje najmanje utrošenog vremena i novčanih sredstava, uz korišćenje raznih meto­da koje dokazuju opravdanost predloženog rešenja.
POVEZANOST SISTEMA ZA UPRAVLJANJE U INDUSTRIJSKIM OKRUŽENJIMA
Authors: Stojačić Stefan
Published: May 2021

U okviru ovog rada razmatra se uticaj povezanosti sistema za upravljanje (SCADA, PLC i DCS) na celokupne performanse upravljanog sistema. Data su osnove karakteristike SCADA, PLC i DCS i njihov međusobni uticaj na  upravljanje.
Aiming for G7 Master Compliance through a Color Managed Workflow: Comparison of Compliance with Amplitude Modulated (AM) vs. Frequency Modulated (FM) Screening of Multicolor Digital Printing
Authors:   Central Connecticut State University, Department of Computer Electronics & Graphics Technology, New Britain, USA, Dharavath Haji Naik
Published: May 2021

The purpose of this research was to determine the influence of screening technologies (AM vs. FM) in the color reproduction aimed at the G7 master compliance. The quality of digital color printing is determined by these influential factors: screening method applied, type of printing process, ink (dry-toner or liquid-toner), printer resolution and the substrate (paper). For this research, only the color printing attributes such as the G7 colors hue and chroma, gray balance, and overall color deviations were analyzed to examine the significant differences that exist between the two screening technologies (AM vs. FM). These are the color attributes which are monitored and managed for quality accuracy during the printing. Printed colorimetry of each screening from the experiment was compared against G7 ColorSpace GRACoL 2013 (CGATS21-2-CRPC6) in CIE L* a* b* space using an IDEAlliance (Chromix/Hutch Color) Curve 4.2.4 application interface with an X-Rite spectrophotometer with an i1iO table. The measured data of each screening were run through this application (Curve 4.2.4). The data of each screening were analyzed by using the Verify Tool of the Curve 4.2.4 application to determine the pass/fail of G7 master compliance levels using G7 ColorSpace tolerances (G7 Grayscale, G7 Targeted, and G7 Colorspace). Analyzed data from the experiment revealed that the printed colorimetric values of each screening (G7 Grayscale, G7 Targeted, and G7 Colorspace) are in match (aligned) with the G7 master compliance levels (reference/target) colorimetric values (G7 Grayscale, G7 Targeted, and G7 Colorspace). Therefore, the press run was passed by the Curve 4 application for both screening technologies tested.
Management of hemoperitoneum due to rupture of the ovarian cyst
Authors: Balalau Oana Denisa , Conea Ileana Maria , Bacalbasa Nicolae , Dumitriu Anca Silvia , Paunica Stana , Vasilache Andrei , Olaru Octavian Gabriel
Published: May 2021

Ovarian cyst is the most common female gynecological pathology and it is characteristic of reproductive age. Its rupture causes the sudden onset of pelvic-abdominal pain, often associated with physical exertion or sexual contact. The differential diagnosis is made with other causes of lower abdominal pain: ectopic pregnancy, adnexal torsion, pelvic inflammatory disease or acute appendicitis. The clinical picture may vary depending on the type of ruptured cyst. Dermoid cyst causes severe symptoms due to chemical peritonitis that occurs in response to extravasation of sebaceous contents in the peritoneal cavity. Surgical treatment is indicated for complicated forms of cystic rupture. Most cases have self-limiting, quantitatively reduced bleeding and spontaneous resorption within a few days. Patients diagnosed with ovarian cyst are recommended for regular ultrasound monitoring to prevent complications such as cystic rupture or adnexal torsion. The identification of any ovarian tumor mass in the woman at menopause requires further investigation to rule out the causes of malignancy.
The comparison between the medical and the surgical management of chronic anal fissures
Authors: Mishra Navneet , Parmar Kamal Kishore , Huda Tanweerul
Published: May 2021

Introduction. Anal fissures can be defined as a tear or a break in the anoderm. Acute fissures do not exceed a 6 week-duration and can be seen as a simple tear in the anoderm along with edema, whereas chronic fissures are longer than 6 weeks. Aim. To compare the efficacy of the medical and surgical options for the treatment of chronic anal fissures and to recommend the appropriate option in terms of their symptomatic relief, healing of fissures and long-term effectiveness. Materials & Methods. A prospective observational study was conducted for a period of 2 years, that is, from October 2018 to October 2020, including a follow-up period of 2 months. A total of 72 patients with chronic anal fissures were included in the study and randomized into two groups, represented by the medical management group and the surgical management group (Lateral Internal Sphincterotomy (LIS)). Results. In the case of the 36 patients with CAF (chronic anal fissure) who underwent surgical management, all 36 (100%) patients had optimal healing of the fissure at 6 weeks. In the case of the 36 patients with CAF who underwent medical management, only 32 (89%) patients had optimal healing of the fissure at 6 weeks, whereas 4 patients failed to heal even after 2 months. Conclusions. Surgical management is the preferable method for chronic anal fissures in comparison to medical management. But the medical management has a role in acting as a bridge to surgical management in patients who are not fit for surgery or do not perceive surgery as an option at the time.
Die Kirchen der Stadt Rom im Mittelalter 1050-1300. Bd. 2. S. Giovanni in Laterano (Corpus Cosmatorum II,2). Mit einem Beitrag von Darko Senekovic über S. Giovanni in Fonte
Authors: Claussen Peter Cornelius
Published: May 2021

Der zweite Band des Katalogs der hochmittelalterlichen Kirchen in Rom ist der päpstlichen Kathedrale S. Giovanni in Laterano gewidmet, der von Konstantin begründeten ersten christlichen Basilika. Erstmals entsteht anhand der Schrift- und Bildquellen eine Vorstellung vom mittelalterlichen Äußeren und Inneren des im Barock völlig umkleideten und im 18. und 19. Jahrhundert weiter veränderten Bauwerks. Rekonstruktionen der untergegangenen Fassade, der Apsis des 13. Jahrhunderts und des Ziboriums vom Magdalenenaltar sowie Untersuchungen über die mittelalterlichen Gräber und den erhaltenen Prachtkreuzgang bereichern das Werk. Im Kontext der kirchlichen Reformbewegung und in Konkurrenz zu der Basilika von St. Peter entwickelt der Lateranklerus seit dem 11. Jahrhundert ein legendenhinterfüttertes ideologisches Selbstbild, das sich sowohl in den Beharrungstendenzen, die in Bau und Ausstattung deutlich werden, als auch in den bedeutenden Erneuerungen des 13. und 14. Jahrhunderts manifestiert.
Awake spine surgery: An eye-opening movement
Authors: Fiani Brian , Reardon Taylor , Selvage Jacob , Dahan Alden , El-Farra Mohamed H. , Endres Philine , Taka Taha , Suliman Yasmine , Rose Alexander
Published: May 2021

Background:

Awake surgery is performed in multiple surgical specialties, but historically, awake surgery in the field of neurosurgery was limited to craniotomies. Over the past two decades, spinal surgeons have pushed for techniques that only require regional anesthesia as they may provide reduced financial burdens on patients, faster recovery times, and better outcomes. The list of awake spine surgeries that have been found in the literature include: laminectomies/discectomies, anterior cervical discectomy and fusions (ACDFs), lumbar fusions, and dorsal column (DC) stimulator placement.

Methods:

An extensive review of the published literature was conducted through PubMed database with articles containing the search term “awake spine surgery.” No date restrictions were used.

Results:

The search yielded 293 related articles. Cross-checking of articles was conducted to exclude of duplicate articles. The articles were screened for their full text and English language availability. We finalized those articles pertaining to the topic. Findings have shown that lumbar laminectomies performed with local anesthesia have shown shorter operating time, less postoperative nausea, lower incidence of urinary retention and spinal headache, and shorter hospital stays when compared to those performed under general anesthesia. Lumbar fusions with local anesthesia showed similar outcomes as patients reported better postoperative function and fewer side effects of general anesthesia. DC stimulator placement performed with local anesthesia is advantageous as it allows real time patient feedback for surgeons as they directly test affected nerves. However, spontaneous movement during the placement of DC stimulators is associated with higher failure rates when compared to general anesthesia (29.7% vs. 14.9%). Studies have shown that the use of local anesthesia during ACDFs has no significant differences when compared to general anesthesia, and patient’s report better tolerated pain with general anesthesia.

Conclusion:

The use of awake spine surgery is beneficial for those who cannot undergo general anesthesia. However, it is limited to patients who can tolerate prone positioning with no central airway (i.e., normal BMI with a healthy airway), have no pre-existing mental health conditions (e.g., anxiety), and require a minimally invasive procedure with a short operating time. Future studies should focus on long-term efficacies of these procedures that provide further insight on the indications and limitations of awake spine surgery.
Chronic subdural hematoma in patients over 65 years old: Results of using a postoperative cognitive evaluation to determine whether to permit return to driving
Authors: Katsuki Masahito , Yasuda Iori , Narita Norio , Ozaki Dan , Sato Yoshimichi , Kato Yuya , Jia Wenting , Nishizawa Taketo , Kochi Ryuzaburo , Sato Kanako , Kawamura Kokoro , Ishida Naoya , Watanabe Ohmi , Cai Siqi , Shimabukuro Shinya , Yokota Kenichi
Published: May 2021

Background:

Chronic subdural hematoma (CSDH) is usually associated with good recovery with burr hole irrigation and postoperative drainage under local anesthesia. In Japan, traffic accidents by the elderly drivers over 65 years old are severely increasing, and there is no consensus on whether or not to return to driving after CSDH treatment. We perform a postoperative cognitive assessment. We retrospectively investigated the return-to-driving rate and associated factors.

Methods:

Of the 45 patients over 65 y.o. and who had usually driven, 30 patients wished to drive again. We performed tests composed of Mini-Mental State Examination (MMSE), line cancellation and line bisection task, Kohs block design test, trail making test (TMT)-A and B, Kana-hiroi test, Rey-Osterrieth complex figure test, and behavioral assessment of the dysexecutive syndrome, in order. When all tests’ scores were better than the cutoff values, we let patients drive again. When some of the scores were worse than the cutoff values, we reevaluated the patients at the outpatient every month. If the patients’ scores could not improve at the outpatient, we recommended them to stop driving.

Results:

Nineteen of 30 patients could return to driving. Worse MMSE, Kohs block design test, TMT-A, TMT-B scores, higher age, dementia, or consciousness disturbance as chief complaints were associated with driving disability.

Conclusion:

CSDH is known as treatable dementia. However, we should perform an objective cognitive assessment before discharge because only 63% of the patients over 65 y.o. who wished to drive could return to driving.
ASUHAN KEBIDANAN PADA IBU HAMIL DENGAN ANEMIA RINGAN DI PMB Hj. DINCE SAFRINA TAHUN 2020
Authors: Siti Nur Aini Siti Nur Aini , Juli Selvi Yanti Juli Selvi Yanti
Published: May 2021

Anemia adalah suatu kondisi medis dimana jumlah sel darah merah atau haemoglobin kurang dari normal. Hal ini dapat menyebabkan masalah kesehatan karena sel darah merah mengandung haemoglobin yang membawa oksigen ke jaringan tubuh. Ibu hamil dikatakan anemia jika ibu hamil dengan kadar Hb <11 gr% pada trimester I dan III atau Hb <10,5 gr% pada trimester II. Ibu hamil dengan kadar Hb 9-10 gr%, termasuk dalam kategori anemia ringan. Tujuan penulisan adalah melaksanakan asuhan kebidanan pada Ny. Y G1P0A0 umur 22 tahun usia kehamilan 28 minggu 3 hari dengan kasus anemia ringan di Praktek Mandiri Bidan Hj. Dince Safrina Tahun 2020. Metode yang digunakan adalah studi kasus dengan pendekatan asuhan kebidanan yaitu SOAP yang meliputi subjektif, objektif, assessment, plan, dan lembar implementasi serta evaluasi, dilaksanakan pada tanggal 09 Juli 2020 sampai 16 Juli 2020 di PMB Hj. Dince Safrina dan di rumah pasien. Hasil asuhan kebidanan yang telah dilakukan terhadap Ny.Y G1P0A0 umur 22 tahun usia kehamilan 28 minggu 3 hari dengan anemia ringan dilakukan dengan memberikan tablet Fe dan sayur bayam sebanyak 300 gram dikonsumsi setiap hari selama 1 minggu, setelah 1 minggu diberikan asuhan ibu mengalami perbaikan Hb 11,2 gr/dL dan tidak ditemukan kesenjangan antara teori dan kasus. Kesimpulan yang ditarik adalah adanya kenaikan Hb pada ibu hamil setelah mengkonsumsi tablet Fe dan sayur bayam selama 1 minggu. Petugas kesehatan diharapkan dapat melakukan promosi kesehatan tentang pentingnya mengkonsumsi tablet Fe yang tepat, makan makanan yang mengandung zat besi, serta vitamin C untuk meningkatkan penyerapan zat besi didalam tubuh.
A Review on Natural Dyes: Raw Materials, Extraction Process, and their Properties
Authors:   Department of Textile Engineering, BGMEA University of Fashion & Technology (BUFT), Bangladesh, ANM Sayem , F Ahmed ,   Department of Textile Engineering, BGMEA University of Fashion & Technology (BUFT), Bangladesh, P Saha ,   Department of Textile Engineering, BGMEA University of Fashion & Technology (BUFT), Bangladesh, B Talukder ,   Department of Textile Engineering, BGMEA University of Fashion & Technology (BUFT), Bangladesh
Published: May 2021

Synthetic dyes and all the processing used in general dyeing is harmful to our health. Dye from natural sources can reduce the risk of synthetic dyes. As indigo has been used for thousands of years for the coloration of textiles as a natural source. This review is aimed at a discussion of different raw materials used for the extraction of natural dyes, the extraction process for different natural dyes, and the properties of fabric dyed by those dyestuffs. Most of the natural dyes showed a very good fastness property in researches. The dyes can be extracted from trees, bark, leaves, flowers, and many more sources. Most of the natural dyes exhibit special properties like anti-microbial, less toxicity, less allergenic, UV protection.
Intermittent Transfusions for Treatment of Thalassemia in the State of Georgia, 2007-2016
Authors:   Department of Pathology, Emory University, USA, MR Rollins , J Boudreaux ,   Department of Pediatrics, Emory University, USA, J Eckman ,   Department of Hematology & Oncology, Emory University, USA, J Branscomb ,   Georgia State University, Andrew Young School of Policy Studies, USA, M Zhou ,   Georgia State University, Andrew Young School of Policy Studies, USA, A Snyder ,   Georgia State University, Andrew Young School of Policy Studies, USA
Published: May 2021

Background: Individuals with Non-Transfusion Dependent Thalassemia (NTDT) may require infrequent transfusions. Knowing transfusion history, while important, can be challenging in this subgroup. Study Design: Hospital discharge data in Georgia (2007-2016) was reviewed. Thalassemia patients were defined as ≥3 encounters with a thalassemia diagnosis code. Transfusion was defined by the presence of a diagnosis, CPT, revenue, or HCPCS code for red cell transfusion. Results: There were 428 patients identified; 57 received multi-site transfusions. Conclusion: Georgia hospitals provide intermittent transfusions to low volumes of probable NTDT patients. Patient and provider education may help assure adherence to best practices, avoiding serious transfusion complications.
Quality of Migrant Care: Results of an Interprofessional Survey
Authors:   Charite - Universitätsmedizin Berlin, Clinic for Gynecology and Center for Oncological Surgery, Berlin, Germany, V Seidel , B Scheffer ,   Charite - Universitätsmedizin Berlin, Clinic for Gynecology and Center for Oncological Surgery, Berlin, Germany, A Heinz ,   Charité - Universitätsmedizin Berlin, Clinic for Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany, U Kluge ,   Charité - Universitätsmedizin Berlin, Clinic for Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany, N Monter ,   Psychiatrie Initiative Berlin Brandenburg des Vereins fur Psychiatrie und seelische Gesundheit e. V, Berlin, Germany, A Holzgreve ,   Vivantes - Hospital Group, Department of Clinical Research and Academic Teaching, Berlin, Germany, MG Inci ,   Charite - Universitätsmedizin Berlin, Clinic for Gynecology and Center for Oncological Surgery, Berlin, Germany, Wegner E Demirbuken ,   Berlin House of Representatives, Committee for Education, Youth and Family, Berlin, Germany, G Jonitz ,   Berlin Chamber of Physicians, Berlin, Germany, J Seybold ,   Deputy Medical Director, Charité - Universitätsmedizin Berlin, Berlin, Germany, J Sehouli ,   Charite - Universitätsmedizin Berlin, Clinic for Gynecology and Center for Oncological Surgery, Berlin, Germany
Published: May 2021

Background: Migration is a global phenomenon. Nevertheless, there are still data lacking about physicians and other health care provider perceptions and expectations concerning the management of patients with migration background. This national survey was therefore conducted. Method: Physicians and psychotherapists working at Charite Universitatsmedizin Berlin and Vivantes Hospital Group clinics, as well as resident doctors and psychotherapists, were invited to participate in this quantitative online-survey. The statistical analysis was anonymous and descriptive. Results: Overall, 355 questionnaires could be analyzed. The quality of care for migrants and non-migrants was rated as “good” or “very good” by at least 88% of the participants. The respondents estimated that 1% of the migrants were “not at all satisfied”. Of the respondents, 58% were dissatisfied at least once a week due to a language barrier. A specific training program on dealing with migrants and migrant care was desired by 61%. Conclusions: The topic of migrant care in the German health care system is relevant. Structured and systematic training on intercultural competence should be offered to improve migrant patient care quality and medical staff satisfaction. Institutionalized professional language translation could possibly improve the satisfaction of migrant patients and medical staff.
Coumarin Luciferins and Mutant Luciferases for Robust Multicomponent Bioluminescence Imaging
Authors: Yao Zi , Caldwell Donald , Love Anna , Kolbaba-Kartchner Bethany , Mills Jeremy , Schnermann Martin , Prescher Jennifer
Published: May 2021

We prepared a new class of luciferins based on a red-shifted coumarin scaffold. These probes (CouLuc-1s) were accessed in a two-step sequence via direct modification of commercial dyes. The bioluminescent properties of the CouLuc-1 analogs were also characterized, and complementary luciferase enzymes were identified using a two-pronged screening strategy. The optimized enzyme-substrate pairs displayed robust photon outputs and emitted a significant portion of near-infrared light. The CouLuc-1 scaffolds are also structurally distinct from existing probes, enabling rapid multicomponent imaging. Collectively, this work provides novel bioluminescent tools along with a blueprint for crafting additional probes for multiplexed imaging