bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevention of Transmission of TB Disease with the Approach of Neuman System Model in Kawangu Community Health Center East Sumba Regency Indonesia
Authors: Gunawan Yosephina Elizabeth Sumartini
Published: June 2019

Introduction: Family empowerment needs to be done to improve the knowledge, awareness and willingness of the family in its efforts to prevent the transmission of TB disease. This study aims to explainÂ  the influence of the approach Neumanâ€™s System Model to the prevention of transmission of TB. Methods: The design of this study is quasy experimental with the approach of the pre-post mehod with control group design. Sample research as many as 32 of the family, namely the 16 families in the treatment group and 16 families in the control group were determined purposively. Results: there is significant effect of treatment against the level of knowledge of the treatment group with z by -2.432 and significant valueÂ  of 0.001 and a significant influence of the treatment given to the prevention control groups with z value -2.039 and significant value of 0.041. Different test showed significant difference on the knowledge of the control group ang the treatment of 0.039 and z values -2.066 and there is a significant difference in prevention efforts of the control group and the treatment of 0.000 with a value of z -4.642. Conclusions: the approach of Neumanâ€™s System Model performed in the treatment group have a significant influence on the increased knowledge and prevention of transmission of TB disease conducted by the family.
Progressive Muscle Relaxation in Reducing Blood Glucose Level among Patients with Type 2 Diabetes
Authors: Agung Akbar Muhammad , Malini Hema , Afriyanti Esi
Published: June 2019

Most of the treatments of patients with type 2 Diabetes MellitusÂ Â (T2DM) who are admitted to the hospital in controlling the blood glucose still concentrated on medication and diet. On the other hand, exercise or activity management, however, gets insufficient consideration. Health professionals, especially nurses, need to be aware that some exercises or activities should be accomplished even for hospitalized patients. The effort to organize physical activity can be achieved by using Progressive Muscle Relaxation (PMR). The purpose of this study was to determine the effect of PMR on reducing the blood glucose levels in patients with T2DM. This research used the quasi-experimental design with one group pretest-posttest approach with control group design. The sampling technique was simple random sampling with 30 samples, 15 in both intervention and control groups. Data collection techniques were performed by measuring the blood glucose levels at that time. The duration of PMR as an intervention was performed for three days on a regular basis. Afterward, we remeasured the blood glucose levels. Data analysis was done by using t-test. The results of data analysis showed that there was a decrease in mean score of blood glucose levels for 63,80 mg/dl in the control group and 80,46 mg/dl in the intervention group.The results showed that PMR was effective in reducing the blood glucose levels of patients with T2DM in the public hospital (p-value = 0.015). The results of this study can be applied by nurses as an alternative intervention in the management of patients with T2DM.

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Family Efforts to Prevent Transmission of Tuberculosis Disease in The Region of Kawangu Community Health Center East Sumba Regency
Authors: Gunawan Yosephina Elizabeth Sumartini
Published: June 2019

Introduction: The family has an important role in the care and treatment of tuberculosis as well as the prevention of transmission of tuberculosis disease in the family or the community. This research aims to identify the family's efforts in preventing the transmission of tuberculosis disease in the region of Kawangu Community Health Center East Sumba Regency. Method: This study is a qualitative research approach phenomenology with the participant as much as 16 people selected by purposive technique. Data collected by conducting structured interviews and dianalis with the technique of content analysis. Result: The theme of the research obtained is as much as 7 themes in a row as follows: the concept of Disease tuberculosis, Cleanliness, Close your mouth when coughing or sneezing, dispose of the saliva in place, Support TB Disease Treatment, improved nutritional Status and puts Sufferers Separately. Conclusion: Although the family has yet to fully grasp the concept of disease of TB but various efforts have been undertaken by the family to prevent the transmission of tuberculosis diseases such as keep clean, reminds patients to cover the mouth when coughing/sneezing and not throw the saliva carelessly. The family also support treatment programs with a role as PMO as well as pay attention to nutrient intake for patients of TB. Other efforts undertaken family is placing the sufferer separately.

Keywords: family efforts, prevent transmission, tuberculosis
THE ROLE OF FOREST ECOSYSTEMS IN THE PROCESS OF MITIGATION AND ADAPTATION TO THE EFFECTS OF CLIMATE CHANGE
Authors: Ristić Ratko , Malušević Ivan , Radić Boris , Milanović Slobodan , Milčanović Vukašin , Polovina Siniša
Published: June 2019

Forest ecosystems provide a wide range of environmental services with an important role in the Earth’s life-support system. Climate change in Southeastern Europe (SEE) and forecasts for the period until 2070 have a huge impact on the present and future planning in forestry and watershed management, due to the observed trends: the increment of mean annual air temperature from 2,5–5,0 °C until the end of the XXI century; redistribution of annual precipitation, with much more precipitation in the spring-summer period, during short, intensive rain events; a decrease of annual precipitation and soil moisture of 10–20 %, with extreme consequences: dieback and disappearance of forests in huge areas of hilly-mountainous regions. Degradation and loss of forests leads to spread and intensification of soil erosion, with frequent torrential floods, mudflows, landslides, and avalanches. Stable forest ecosystems are pillars of sustainable development, repopulation and could provide means and resources to battle and overcome poverty in moun-tainous regions of southeast Europe.
DISTRIBUTION OF CHEMICAL ELEMENTS IN SOIL FROM CRN DRIM RIVER BASIN, REPUBLIC OF MACEDONIA
Authors: Stafilov Trajče , Šajn Robert , Mickovska Ivana
Published: June 2019

The aim of this study was to investigate the distribution of chemical elements in topsoil and subsoil, focusing on the identification of natural and anthropogenic element sources in the area of the Crn Drim River Basin, Republic of Macedonia. For that purpose, by using sampling network of 5 × 5 km, 124 soil samples from 62 locations (topsoil and bottom soil) were collected. In total 60 elements were analysed, from which 18 elements (Ag, Al, B, Ba, Ca, Cr, Cu, Fe, K, Li, Mg, Mn, Na, Ni, P, Pb, V и Zn) were analysed by inductively coupled plasma - atomic emission spectrometry (ICP-AES) and an additional 42 elements were analysed by ICP - mass spectrometry (ICP-MS). Multivariate statistical analysis was applied to the obtained data. Factor analysis applied to the ICP-AES results produced four geogenic fac-tors: F1 (Ba and K); F2 (Ag, Cd, Cu, Ni, Pb and Zn), F3 (Cr, Fe, Na, Ni and V) and F4 (Al, Ca, Mg and Mn). Data ob-tained from the distribution maps and data analysis on soil samples, indicate the natural occurrence of the analysed ele-ments as well as low concentrations of heavy metals in the studied area.
Psychometric Characteristics of the Physical Activity Enjoyment Scale in the context of Outdoor Activity
Authors: Fuentesal-Garcia Julio , Baena-Extremera Antonio , Sáez-Padilla Jesús
Published: June 2019

The aim of this study was to assess the psychometric properties of the Physical Activity Enjoyment Scale in the context of outdoor physical activities. In order to do this, we carried out a research in some Primary and Secondary school l located in western Andalucía (Spain), with kids aged 9-12 years old [M= 11.22; SD= 1.07), therefore a sample of 455 students (228 boys= 50.1% 227 girls = 49.9% = 50.1) was used]. Descriptive, exploratory and confirmatory analyses were conducted. We also analyzed several factors such as internal consistency, composite reliability, average variance extracted and convergent validity. Afterwards, differences by gender and school year were also studied. Data showed the need to eliminate many of the items from the original scale, giving as a result a model of 5 items with satisfactory fit in the confirmatory analysis. The ANOVA statistical test carried out in terms of sex and school year didn’t show any tangible difference between the target groups.
Self-Employment in Times of Crisis: The Case of the Spanish Financial Crisis
Authors: Contreras Sergio
Published: June 2019

While some researchers have suggested that the self-employment (SE) sector is a haven during a financial Crisis, others believe that SE is not necessarily the desired outcome, but an indicator that the labor market is tightening for some groups. Few researchers have compared the SE sector before and after the occurrence of a significant financial Crisis, especially in developed countries. This paper analyzes the determinants of entry into self-employment during the 2008 Spanish Crisis. Using data from the Encuesta de Presupuesto Familiar (EPF), results show that although the rate of SE did not experience a significant change during this time the Crisis affected people differently based on gender, with being females more affected than males. Results also suggest differences between Comunidades Autonomas in how the self-employment sector behaved during the Crisis.
Fast and Effective Techniques for LWIR Radiative Transfer Modeling: A Dimension Reduction Approach
Authors: Westing Nicholas , Borghetti Brett , Gross Kevin
Published: June 2019

The increasing spatial and spectral resolution of hyperspectral imagers yields detailed spectroscopy measurements from both space-based and airborne platforms. Machine learning algorithms have achieved state-of-the-art material classification performance on benchmark hyperspectral data sets; however, these techniques often do not consider varying atmospheric conditions experienced in a real-world detection scenario. To reduce the impact of atmospheric effects in the at-sensor signal, atmospheric compensation must be performed. Radiative Transfer (RT) modeling can generate high-fidelity atmospheric estimates at detailed spectral resolutions, but is often too time-consuming for real-time detection scenarios. This research utilizes machine learning methods to perform dimension reduction on the transmittance, upwelling radiance, and downwelling radiance (TUD) data to create high accuracy atmospheric estimates with lower computational cost than RT modeling. The utility of this approach is investigated using the instrument line shape for the Mako long-wave infrared hyperspectral sensor. This study employs physics-based metrics and loss functions to identify promising dimension reduction techniques. As a result, TUD vectors can be produced in real-time allowing for atmospheric compensation across diverse remote sensing scenarios.
Supplementing L-Isoleucine Increases Medium Protein and Alters the Expression of Genes and Proteins Involved in Milk Protein Synthesis and Energy Metabolism in Bovine Mammary Cells
Authors: Conejos Jay Ronel , Lee Jae-Sung , Park Jin-Seung , Moon Jun-Ok , Lee Hong-Gu
Published: June 2019

The objective of this study was to determine the effects of supplementing L-isoleucine (L-Ile) on milk protein synthesis, using an immortalized bovine mammary epithelial (MAC-T) cell line. In this case, the cells were treated with 0, 0.3, 0.6, 0.9, 1.2 and 1.5 mM of supplemental Isoleucine (Ile), and the most efficient time for protein synthesis for each amino acid was determined by measuring the cell, medium and total protein at 0, 24, 48, 72 and 96 h. Confirmatory tests showed that 48h incubation time and 0.6 mM dosage of L-Ile are considered as the optimal time and dosage. The mechanism of milk protein synthesis was elucidated through proteomics analysis to clarify the metabolic pathway. When the L-Ile was supplemented, extracellular protein (medium protein) reached a peak at 48h, whereas in the case of the intracellular cell protein, it was shown to have reached to its peak at 24h in all L-Ile dosage treatments. In total, it is noted that there were 63 upregulated and 52 downregulated proteins. The results of the protein pathway analysis showed that the L-Ile group stimulated insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade, insulin/IGF pathway-protein kinase B signaling cascade, p53 pathway, de novo purine biosynthesis, Wnt signaling pathway, glycolysis, pentose phosphate pathway, and ATP synthesis which are pathways involved and related to protein and energy metabolism. Together, these results demonstrate that L-Ile supplementation was effective in stimulating β-casein synthesis by stimulating genes and pathways which are significantly related to protein and energy metabolism.
Parasites and Fungi Characteristics on Short Finned Eel Anguilla marmorata in Central Sulawesi, Indonesia
Authors: Amrullah Amrullah , Rosyida Eka , Ardiansyah Ardiansyah , Hartinah Hartinah , Wahidah Wahidah
Published: June 2019

Parasitic infections are often not the direct cause of death of fish but the presence of wounds in the fish's body due to parasitic attacks is a trigger factor for secondary infection. Secondary infections can be caused by fungi, bacteria or viruses, which ultimately cause the death of fish. This study aimed to determine the characteristics of parasites and fungi that infected eel (Anguilla sp.) in the waters of Poso, Buol, Toli-toli and Donggala, Central Sulawesi as an important part of the diagnosis of fish disease in the framework of teraupetic strategies. Eel were taken as many as 30 individuals / location for observation of parasites and fungi. Parasitological examination was carried out for external and internal parasites on the mucous layer of the body, gills, intestines and stomach, while fungal isolations were carried out on muscles, skin and tissues that have abnormalities. After identification, the prevalence and intensity were carried out. The results showed that the highest prevalence of parasites were Camallanus sp (70%), Proteacephalus sp (50%) and Gyrodactylus sp (40%), and the nematode Camallanus sp the tapeworm Proteocephalus sp had the highest intensity of 57.5 and 30.8 respectively. Fungal prevalence were found highest in Saprolegnia sp (36%), and Fusarium sp (32%).
Quantile Regression with Telematics Information to Assess the Risk of Driving Above the Posted Speed Limit
Authors: Pérez-Marin Ana M. , Guillen Montserrat , Alcañiz Manuela , Bermúdez Lluís
Published: June 2019

We analyze real telematics information for a sample of drivers with usage-based insurance policies. We examine the statistical distribution of distance driven above the posted speed limit – which presents a strong positive asymmetry – using quantile regression models. We find that, at different percentile levels, the distance driven at speeds above the posted limit depends on total distance driven and, more generally, on such factors as the percentages of urban and nighttime driving and on the driver’s gender. However, the impact of these covariates differs according to the percentile level. We stress the importance of understanding telematics information, which should not be limited to simply characterizing average drivers, but can be useful for signaling dangerous driving by predicting quantiles associated with specific driver characteristics. We conclude that the risk of driving long distances above the speed limit is heterogeneous and, moreover, we show that prevention campaigns should target primarily male, non-urban drivers, especially if they present a high percentage of nighttime driving.
Evaluating Landslide Remediation Methods Used in the Carpathian Mountains, Poland
Authors: Bednarczyk Zbigniew
Published: June 2019

The aim of this study was to evaluate the results of landslide remediation in the Polish Carpathians. The research for safeguarding the roads and infrastructure was conducted in the years 2005–2018 in nine landslide areas. The interpretation of engineering geology conditions was complex due to the soil-rock nature of the flysch sediment. Movements were activated after heavy rainfalls. In two cases, triggers were connected with the undercutting of the slope or external loading. The research methods included mapping, drilling, index, oedometer, direct shear tests, ground-penetrating radar scanning, and numerical modeling. To date, 15–59 series of inclinometer and piezometer network readings in 30 locations have been taken. Three online stations have been delivering continuous, nearly real-time data since May 2010. Displacements before the remediation ranged from a few millimeters to several centimeters. The proposed remediation methods included piles, micropiles, anchors, retaining walls, and drainage systems. Six stabilization projects were prepared and checked using the limit equilibrium method and finite element method modeling. The research shows that in five landslide areas, the proposed remedial works were effective. Two other partial stabilization works limited the scope of the movements but did not eliminate the risk. At two locations, only temporary repairs were conducted. Proper identification of the landslide triggers and activity is standard for the recognition of counteraction possibilities and could lower stabilization costs. The selected methods delivered data for remedial decisions. However, effective remediation of an active Carpathian landslide is difficult. It requires individually calibrated investigations, representative monitoring, and careful design of stabilization.
LAS RESOLUCIONES DE LA DIRECCIÓN GENERAL DE LOS REGISTROS Y DEL NOTARIADO SOBRE RETRIBUCIÓN DE ADMINISTRADORES DESPUÉS DE LA SENTENCIA DEL TRIBUNAL SUPREMO DE 26 DE FEBRERO DE 2018: ¿FLEXIBILIDAD O FRAGILIDAD?
Authors: Ortiz del Valle Mª del Carmen
Published: June 2019

Una de las cuestiones que más debate ha suscitado desde siempre en el ámbito del derecho de sociedades es el relativo a la retribución de los consejeros ejecutivos y, en concreto, en lo que se refiere a la constancia estatutaria de su retribución. De ahí la importancia de la Sentencia del Tribunal Supremo de 26 de febrero de 2018 (RJ 2018, 635) y de las resoluciones de la Dirección General de los Registros y del Notariado (en adelante DGRN) surgidas con posterioridad a la misma.
Add-on effect of Kinesiotape in patients with acute lateral ankle sprain: a randomizedcontrolled trial
Authors: Shin Jeong-Cheol , Kim Jae-Hong , Nam Dongwoo , Park Gwang-Cheon , Lee Jeong-Soon
Published: June 2019

Background

Evidence on the add-on effect of Kinesiotape (KT) on acupuncture for treating ankle sprains remains insufficient. We assessed the add-on effect of KT on ankle sprain by comparing acupuncture combined with KT(AcuKT) with acupuncture alone in patients with acute lateral ankle sprain (ALAS).

Methods

This study was a multicenter, randomized, controlled clinical trial that included a per-protocol analysis of the add-on effect of KT on ALAS. The randomization was software-based and only the assessors were blinded. Sixty participants(20 each from three centers) with grade I or II ALAS were randomly assigned to an acupuncture (n=30) or AcuKT (n=30) group. Both groups received acupuncture treatment once daily, 5 days per week for 1 week. The AcuKT group received additional KT treatment. Visual analog scale (VAS) scores for pain and Foot and Ankle Outcome Score (FAOS) were obtained, and edema measurements were performed at baseline (week 0), at the end of the intervention (week 1), and at 4 weeks after the intervention (week 5).The European Quality of Life Five Dimension-Five Level Scale (EQ-5D-5L) measurements were conducted at week 0, week 1, week 5, and 26 weeks after the intervention. The number of recurrent ankle sprains was determined at 4,8,12, and 26weeks after the intervention.

Results

Fifty-six patients with ALAS completed the trial (AcuKT group, 27; acupuncture group, 29). There were significant changes(week 0 vs. week 1;week 0 vs. week 5) in VAS, FAOS, and EQ-5D-5L in both groups and in edema measurement in the AcuKT group alone. There were no significant differences between both groups regarding any outcome and in a subanalysis based on symptom severity.

Conclusions

These results indicate that AcuKT did not show the positive add-on effects of KT on acupuncture regarding pain reduction, edema, recovery of function, activities of daily living, quality of life, and relapse of ALAS.
Preventing acute kidney injury in high-risk patients by temporarily discontinuing medication – an observational study in general practice
Authors: Faber Suzanne J , Scherpbier Nynke , Peters Hans , Uijen Annemarie
Published: June 2019

Background

Elderly, patients with chronic kidney disease (CKD) and patients with heart failure who continue using renin-angiotensin-aldosterone-system (RAAS) inhibitors, diuretics, or non-steroidal-anti-inflammatory drugs (NSAIDs) during times of fluid loss have a high risk of developing complications like acute kidney injury (AKI). The aim of this study was to assess how often advice to discontinue high-risk medication was offered to high-risk patients consulting the general practitioner (GP) with increased fluid loss. Furthermore, we assessed the number and nature of the complications that occurred after GP consultation.

Methods

We performed a cross-sectional study with patients from seven Dutch general practices participating in the Family Medicine Network between 1-6-2013 and 1-7-2018. We included patients who used RAAS-inhibitors, diuretics, or NSAIDs, and had at least one of the following risk factors: age ≥70 years, CKD, or heart failure. From this population, we selected patients with a ‘dehydration-risk’ episode (vomiting, diarrhoea, fever, chills, or gastrointestinal infection). We manually checked their electronic patient files and assessed the percentage of episodes in which advice to discontinue the high-risk medication was offered and whether a complication occurred in three months after the ‘dehydration-risk’ episode.

Results

We included 3607 high-risk patients from a total of 44.675 patients (8.1%). We found that patients were advised to discontinue the high-risk medication in 38 (4.6%) of 816 ‘dehydration-risk’ episodes. In 59 of 816 episodes (7.1%) complications (mainly AKI) occurred.

Conclusions

Dutch GPs do not frequently advise high-risk patients to discontinue high-risk medication during ‘dehydration-risk’ episodes. Complications occur frequently. Timely discontinuation of high-risk medication needs attention.
Multi-Drug Resistant, Extended Spectrum β-Lactamase and Carbapenemase Producing Bacterial Isolates among Septicemia Suspected under Five Children in Tikur Anbesa Specialized Hospital, Addis Ababa Ethiopia
Authors: Mitiku Mequanint , Ayenew Zeleke , Mitiku Mequanint
Published: June 2019

Background: Bloodstream infections due to bacterial pathogens are a major cause of morbidity and mortality among pediatric patients. Emergence of drug resistance in high classes of antibiotics among the bacterial pathogens is another issue of the public health concern. Objective: To determine Multi-drug resistant, extended spectrum β-lactamase and carbapenemase producing bacterial isolates among septicemia suspected under five Children in Tikur Anbesa Specialized Hospital, Addis Ababa Ethiopia. Methods: Across-sectional study was conducted from September 2017 to June 2018 among pediatric patients with febrile illness aged under five in Tikur Anbesa Specialized Hospital. 340 Blood samples were collected and processed following standard microbiological techniques and culture was performed using BacT/Alert machine in combination with conventional method. AST of the isolates was performed by Kirby-Bauer disc diffusion method and MIC technique Result: A total of 137(40.2%) bacterial pathogens were isolated from 340 pediatric patients suspected of BSI with febrile illness. Of these isolates 54% were Gram negative bacteria. Of the isolates 43 (31.4%) Klebsiella pneumonia Acinitobactor species were the most frequently isolated pathogens. Klebsiella pneumoniae isolates were 95.6% MDR, 23.7% ESBL, and 27.1% CRE in children.Conclusion: In this study, Klebsiella pneumoniae and S. aureus are common pathogens associated with BSI in pediatrics with high antimicrobial resistance. The prevalence of MDR 51.1%, CRE 30.5% and ESBL 25.4% were alarmingly high in bacterial isolates. ESBL producing organisms were common in Klebsiella species and Escherichia coli isolates. Since most of isolates exhibit multidrug resistant, invitro- susceptibility of antimicrobials is mandatory. Strengthing antimicrobial surveillance system and antimicrobial stewardship are necessary for better management of antibiotics in addition to infection prevention practice in TASH settings.
Ancient DNAs and the Neolithic Chinese super-grandfather Y haplotypes
Authors: Zhang Ye , Lei Xiaoyun , Chen Hongyao , Li Jiawei , Zhou Hui , Huang Shi
Published: June 2019

Background

Previous studies identified 3 Neolithic Han Chinese super-grandfather Y haplotypes, O2a2b1a1a-F5, O2a2b1a2a1-F46, and O2a1b1a1a1a-F11, but their relationships with the archaeological and written records remain unexplored.

Results

We here report genome wide DNA data for 11 ancient samples (0.02x-1.28x) from China ranging from 6500 to 2500 years before present (YBP), which also includes ~11 Mb Y NRY data for one sample. The 11 ancient samples belonged to 4 different genetic groups, designated as Dashanqian (DSQ) of Xiajiadian Culture in the Northeast, Duzhong (DZ) of late Yangshao Culture in the Central Plains, Zhengzhou Xishan (ZX) of Miaodigou Culture in the Central Plains, and Others. Present day F5 samples were closer in autosomal distances to the ZX and DSQ groups while O1, O2, and C samples were closer to the DZ group. We also sequenced the Y chromosome of one of these ancient samples K12 from DSQ and found both K12 and a previously reported ~4000 year old sample MG48 from Northwest China to have the O2a2b1a1a1a2a-F2137 haplotype, belonging to the most prolific branch O2a2b1a1a1-F438 immediately under F5. We further found close relationships between ZX and DSQ and between ZX and ancient M117 Tibetans or present day Southwest Dai Chinese carrying the F5 subtype O2a2b1a1a6.

Conclusions

The results imply radiations of F5 subtypes from the putative place of F5 origin in Henan. These results are remarkably consistent with archaeological and written records.
Genome-wide association study reveals new loci for yield-related traits in Sichuan wheat germplasm under stripe rust stress
Authors: Ye Xueling , Li Jian , Cheng Yukun , Yao Fangjie , Long Li , Wang Yuqi , Wu Yu , Li Jing , Wang Jirui , Jiang Qiantao , Kang Houyang , Li Wei , Qi Pengfei , Lan Xiujin , Ma Jian , Liu Yaxi , Jiang Yunfeng , Wei Yuming , Chen Xianming , Liu Chunji , Zheng Youliang , Chen Guoyue
Published: June 2019

Background

As one of the most important food crops in the world, increasing wheat (Triticum aestivum L.) yield is an urgent task for global food security under the continuous threat of stripe rust (caused by Puccinia striiformis f. sp. tritici) in many regions of the world. Molecular marker-assisted breeding is one of the most efficient ways to increase yield. Here, we identified loci associated to multi-environmental yield-related traits under stripe rust stress in 244 wheat accessions from Sichuan Province through genome-wide association study (GWAS) using 44059 polymorphic markers from the 55K single nucleotide polymorphism (SNP) chip.

Results

A total of 13 stable quantitative trait loci (QTLs) were found to be highly associating to yield-related traits, including 6 for spike length (SL), 3 for thousand-kernel weight (TKW), 2 for kernel weight per spike (KWPS), and 2 for both TKW and KWPS, in at least two test environments under stripe rust stress conditions. Of them, ten QTLs were overlapped or very close to the reported QTLs, three QTLs, QSL.sicau-1AL, QTKW.sicau-4AL, and QKWPS.sicau-4AL.1, were potentially novel through the physical location comparison with previous QTLs. Further, twenty-one candidate genes within three potentially novel QTLs were identified, they were mainly involved in the regulation of phytohormone, cell division and proliferation, meristem development, plant or organ development, and carbohydrate transport.

Conclusions

QTLs and candidate genes detected in our study for yield-related traits under stripe rust stress will facilitate elucidating genetic basis of yield-related trait and could be used in marker-assisted selection in wheat yield breeding.
Competition at product markets of various types of commodities
Authors: Umantsiv Iurii , Sonko Yuliіa , Yatsyshyna Klavdiia
Published: June 2019

This article is devoted to researching the peculiarities of the competitive environment at the markets of various types of commodities (goods). Competition analysis allows making conclusions about the effectiveness of the market to identify the factors of development, market infrastructure weaknesses and provide recommendations to address these problems, and to identify priorities for the market competition development. This, in turn, will contribute to finding ways to improve the competitiveness of products. Timely and adequate assessment of the level of competition is not just a part of analytical instruments for the research of the market environment; this is a necessary condition for effective activity of market participants. The peculiarities of competition at the markets of various types of goods were analyzed: the flower market, the juice market and the market for consulting services. In the course of the research, there were determined the factors that influence the competition, also were identified the main trends of its development.
Bilateral complicated ovarian cysts of the fetus
Authors: N.V. Mashinets, V.N. Demidov
Published: June 2019

Case report of prenatal diagnosis of bilateral complicated ovarian cysts of the fetus at 34 weeks of pregnancy
is presented. The particularity of this case is that one ovarian cyst in the fetus was complicated by intrauterine
torsion, which required surgical treatment after birth. In the cavity of the second cyst, hemorrhage occurred
with spontaneous regression, which did not require surgical intervention.
Involution of uterus in postpartum period in ultrasound examination
Authors: I.A. Ozerskaya
Published: June 2019

Retrospective analysis of 558 women in postpartum period is presented. In all cases delivery was urgent, one
live fetus; vaginal birth happened at 454 (81.4%) patients and by Caesarean section — 104 (18.6%). Ultrasound
examination was performed by one doctor, using transabdominal access. The value for assessment of a current
of postpartum period has a condition of a cavity of the uterus which decreases on thickness and the volume.
Advancement of uterine cavity contraction compared with myometrium shows the ratio of cavity volume to
uterine volume, which decreases from 8.0% on day 3 to 4.7% on the 5th day. In a cases of hematometra, no
significant increase in uterine volume was obtained.
A case of mucolipidosis II / manifested as chondrodysplasia punctata in
a second trimester fetus
Authors: A.A. Gusina , I.V. Novikova , S.K. Kleckii
Published: June 2019

The case of mucolipidosis II / in a second trimester fetus is presented. At the ultrasound examination at
20 weeks of gestation intrauterine growth restriction, abnormal profile with flattened nose, polyhydramnios and
premature maturation of the placenta were detected. Autopsy subsequent to the termination of pregnancy revealed
intrauterine growth restriction, shortening of the lower limbs, pronounced facial dysmorphism. The radiograph
showed a significant shortening of the long tubular bones, sclerosis of the skull base, reduced mineralization of the
bones of the facial skull, calcifications in the vertebral bodies of the cervical and sacral spine, proximal epiphysis
of the left humerus and femurs, heel and talus. Microscopic examination of the placenta revealed pale-colored
villi with diffuse pronounced vacuolization of syncytiotrophoblast cells, Hofbauer — Kashchenko cells, and
unvillous trophoblast, focal calcification of the basement membranes of the villi in the form of linear deposits.
A molecular genetic study revealed a compound heterozygous carriage of the mutations p.Asp919GlufsTer21
and p.Arg1189Ter in 14 and 19 exons of the GNPTAB gene and the diagnosis mucolipidosis II alpha/beta was
established.
Consórcio de educação de Barcelona: evidências de gestão compartilhada de serviços educativos via consórcios públicos
Authors: Strelec Thamara Caroline , Costa Valeriano Mendes Ferreira , Calderon Raquel Gallego
Published: June 2019

Partindo da inexistência no Brasil de consórcios públicos exclusivamente de educação nos termos da Lei de Consórcios Públicos (Lei nº 11.107/2005), este artigo toma como referência o Consórcio de Educación de Barcelona, experiência única na Espanha de gestão compartilhada de redes públicas de ensino entre governos, com o objetivo de compreender seu modelo de gestão e identificar seus resultados e desafios. Por meio de um estudo de caso, constataram-se limitações para a implementação de programas e desafios oriundos das preferências e herança dos governos, embora o consórcio tenha permitido a superação de problemas na cobertura da rede de atendimento e de sobreposições na gestão
Rola chirurgii i radioterapii w leczeniu przerzutów raka piersi do mózgu
Authors: Urbański Bartosz
Published: June 2019

Rak piersi jest drugim najczęstszym nowotworem związanym z przerzutami do ośrodkowego układu nerwowego, w tym głównie mózgu. Związane jest to z wieloma czynnikami, z których najważniejsze to podtyp molekularny raka piersi oraz wiek chorej.Rozsiew raka do mózgu związany jest z bardzo niekorzystnym rokowanie. Dlatego niezykle ważne jest właściwe postępowanie miejscowe tak, aby maksymalnie zwiększyć szanse chorej na wydłużenie życia.
Rola układu immunologicznego w patogenezie oraz progresji płaskonabłonkowego raka głowy i szyi
Authors: Maćkowska Natalia , Sobecka Agnieszka , Golusiński Wojciech , Suchorska Wiktoria M.
Published: June 2019

Płaskonabłonkowy rak głowy i szyi (HNSCC, ang. Head and Neck Squamous Cell Carcinoma) to nowotwór wywodzący się z komórek płaskonabłonkowych błon śluzowych jamy ustnej,  nosa lub gardła. Pomimo znacznych postępów konwencjonalnych metod leczenia, 5-letni wskaźnik przeżycia bez progresji u pacjentów z miejscowo zaawansowanym HNSCC HPV(-)  nadal nie przekracza 50%. Niskie wskaźniki przeżycia w połączeniu z wysoką toksycznością stosowanych terapii, podkreślają konieczność wprowadzenia nowych strategii terapeutycznych. Obecne badania potwierdzają, że układ immunologiczny odgrywa kluczową rolę w patogenezie HNSCC. Lepsze zrozumienie mechanizmów molekularnych odpowiedzialnych za ucieczkę komórek nowotworowych spod kontroli układu immunologicznego oraz dokładne poznanie szlaków molekularnych odpowiedzialnych za rozwój płaskonabłonkowego raka głowy i szyi umożliwi opracowanie bardziej efektywnych terapii. Celem pracy jest przegląd wiedzy dotyczącej roli układu odpornościowego w ucieczce komórek nowotworowych HNSCC spod nadzoru immunologicznego.
Microbiome network analysis of co-occurrence patterns in anaerobic co-digestion of sewage sludge and food waste
Authors: Orellana Esteban , Davies-Sala Carol , Guerrero Leandro D. , Vardé Ignacio , Altina Melisa , Lorenzo María Cielo , Figuerola Eva L. , Pontiggia Rodrigo M. , Erijman Leonardo
Published: June 2019

Addition of food waste (FW) as a co-substrate in anaerobic digesters of wastewater treatment plants is a desirable strategy towards achievement of the potential of wastewater treatment plants to become energy-neutral, diverting at the same time organic waste from landfills. Because substrate type is a driver of variations in phylogenetic structure of digester microbiomes, it is critical to understand how microbial communities respond to changes in substrate composition and concentration. In this work, high throughput sequencing was used to monitor the dynamics of microbiome changes in four parallel laboratory-scale anaerobic digesters treating sewage sludge during acclimation to an increasing amount of food waste. A co-occurrence network was constructed using data from 49 metagenomes sampled over the 161 days of the digesters' operation. More than half of the nodes in the network were clustered in two major modules, i.e. groups of highly interconnected taxa that had much fewer connections with taxa outside the group. The dynamics of co-occurrence networks evidenced shifts that occurred within microbial communities due to the addition of food waste in the co-digestion process. A diverse and reproducible group of hydrolytic and fermentative bacteria, syntrophic bacteria and methanogenic archaea appeared to grow in a concerted fashion to allow stable performance of anaerobic co-digestion at high FW.
Escuela Normal colombiana frente a las disposiciones legales. Tensiones pedagógicas y administrativas
Authors: Rátiva-Velandia Marlén
Published: June 2019

El presente texto está organizado en cinco etapas que caracterizan el desarrollo de las Escuelas Normales en Colombia. Este es el resultado de la primera fase de la tesis doctoral La Escuela Normal Superior de Cartagena de Indias, una historia en construcción. Mirada a la Práctica Pedagógica de 1998 a 2010, investigación histórica, cuyo objetivo fue el de identificar las tensiones pedagógicas y administrativas entre las instituciones (Escuelas Normales) y la normatividad. Para esto se realizó la revisión bibliográfica consultando fuentes como: artículos, informes, tesis, investigaciones, decretos, resoluciones y leyes que hacen parte de la normatividad colombiana sobre Escuelas Normales desde sus orígenes hasta los años noventa. De esta fase se concluye que las Escuelas Normales colombianas y el magisterio colombiano han superado los retos plasmados en las políticas educativas, las adversidades como el cierre constante de establecimientos y la arremetida en 1978 del cierre de 147 Escuelas Normales. No obstante, cabe señalar que algunos decretos y resoluciones terminaron siendo guía para reformas pertinentes en las mismas.
MODIFICATION OF TOOL FOR MOVING TRACK SEGMENTS IN DELTA DESIGN CAD
Authors: Gladkevich A. Yu.
Published: June 2019

Describes the process of improving and developing tools in computer‑aided design system Delta Design. Currently, the modern  process of PCB development is quite complex and time‑consuming process. Existing CAD systems make it easier to design a  printed circuit Board model by providing powerful development tools. Along with the increasing complexity of modern printed  circuit boards, the requirements for development tools are also growing, making them constantly improve. Using the example  of  the  Delta  Design  system,  the  process  of  improving  the  tool  for  moving  track  segments  is  described.  The  analysis  of  the  advantages and disadvantages of the existing tool is made, and the decision on the need to develop a new algorithm is justified.  Of the two proposed variants of such an algorithm, the optimal one was chosen in terms of the quality of the result obtained and  the convenience of operation.
UNIVERSAL CYBER PLATFORM. ADVANCED COMPUTING SYSTEM. ALTERNATIVE BASIC COMPUTATIONAL TECHNOLOGY FOR CONSTRUCTING AN INTELLIGENT AGENT ROBOTIC SYSTEMS
Authors: Danishevskiy O. V. , Parfenov A. V.
Published: June 2019

The  article  gives  a  brief  description  of  the  promising  research  work  on  the  creation  of  a  universal  cybernetic  platform  for  the  study  of  conceptual  solutions  and the  formation  of  scientific  and technical  reserve  in  the  field  of  breakthrough  technologies  of  artificial  intelligence  and  robotics.  An  alternative  approach  to  the  design  of  a  robotic  complex  control  system  in  the  form  of  a  distributed  intelligent  computing  system, the  basic technology  of  which  is  an  Advanced  Computing  System  (ACS), is  presented.  Describes  a  brief  history   of   the   origins   and   features   of   the   Forth   language, it   is  the  enhanced   dialect   and   also   considered   the  varian  t of execution of  the   Forth  and  its   application   in  the   construction of   neural networks.   A  number   of advantages   of  ACS   built  on  microcontroller   Forth‑machines   are   listed in comparison   with computing systems   that use   well‑known   processors of high  level  of integration, requiring   resource‑intensive   hardware   and software   for their   development.
INFORMATION AND LOGISTICS TECHNOLOGIES AS FOUNDATION OF LEAN MANUFACTURING AT DEFENSE INDUSTRY ENTERPRISES
Authors: Surovtseva T. G. , Andreev I. A.
Published: June 2019

The  article  describes  the  existing  information  and  logistics  technologies  (ILT)  and  management  information  systems  (MIS).  Currently  there  are  several  difficulties  with  the  use  of  ILT  and  MIS  in  the  field  of  military‑industrial  complex  (MIC).  Defense  enterprises need competent implementation and application of modern ILT and IMS to optimize their production and economic  activities and reduce costs in the production of products. The essence of the methodology of lean manufacturing (LM) based on  the application of ILT is revealed. The concept of LM is aimed at managing the production enterprise and is used to reduce all  types of losses in material and information flows of value creation. Describes the experience of LM implementation at Obukhovsky  zavod. Examples of application of LM tools in the implementation of production projects are given.
MODERN SOLUTIONS IN THE FIELD OF ROBOTIC VISION TO CREATE A UNIVERSAL CYBERNETIC PLATFORM
Authors: Danishevskiy O. V. , Parfenov A. V. , Stankevich V. V.
Published: June 2019

The article describes modern solutions used to create vision systems for autonomous robotic complexes, a device for controlling  video sensors, methods for obtaining stereo images, processing and further using them in the navigation system. A functional  diagram of the organization of the robotic vision system, which is part of the NIIVK M. A. Kartsev Computing System Research  and Development Institute, platform, a brief description of its functions and principles of action. The proposed solution involves  placing a pair of optical sensors in the head of the robot, simulating the binocular stereoscopic vision inherent in higher animals.  A feature of the development is the rejection of the use of laser, infrared, radio frequency, ultrasound and other active emitters,  which reduces energy costs and the cost of products without reducing their reliability.
AUTOMATIC DEVICE FOR REAL–TIME SWITCHING TO RESERVE RADIO CHANNEL
Authors: Skvarnik I. S. , Shmakov A. A. , Shentyabin A. N. , Minin I. V.
Published: June 2019

Guaranteed delivery of information via communication channels remains an urgent task for a number of industries. However,  automatic transition to the reserve for analog communication channels requires non‑standard solutions. In the proposed device,  the decision on switching to the reserve is made on the basis of spectral analysis of signals transmitted via the main and backup communication channels. A wired communication channel is considered as the main channel, and a wireless broadband access  channel  is  used  as  a  backup  channel. The  signal  transmitted  over  the  wireless  broadband  access  is  taken  as  a  reference  because it is of high quality and which we can influence when building a network. The spectrum of analog signals is calculated on  the basis of the fast Fourier transform, the implementation of which is carried out in the analog signal block based on the STM‑32  microcontroller. The device provides a transition to the reserve in real time.
METHODS FOR IMPLEMENTING NEURAL NETWORK HYDROACOUSTICS ALGORITHMS BASED ON HETEROGENEOUS HARDWARE PLATFORM GRIFON
Authors: Alekseev G. G. , Alekseeva E. A. , Galagan P. V. , Sorokin A. P. , Sorokin S. А.
Published: June 2019

Recently, there has been an increase of interest in creating new neural network hydroacoustics algorithms, for example, test sites  in the Arctic are being created to evaluate the effectiveness of target detection and to ensure the safety of the Canadian North.  The open architecture allows you to adapt hardware to new threats or economic interests. Not only the equipment of radiation and  reception of hydroacoustic systems is improved, but also their processing. The article discusses the ways of improvement and the  principles of building specialized computers based on the GRIFON hardware platform, providing control and signal processing  in mobile and stationary sonar systems. We consider an example of creating a complex that demonstrates the capabilities of  the equipment and the prospects for creating calculators with high parameters and minimal mass‑dimensional characteristics.  Described in detail the structure and principles of the mathematical software of specialized computer. Comparative characteristics  of the proposed algorithms that can be used to optimize signal processing paths and the volume of digital equipment are given.
USE OF DEEP MACHINE LEARNING METHODS OF ARTIFICIAL NEURAL NETWORKS FOR DESIGNING ALGORITHMS OF ELECTROMYOGRAPHY SIGNAL RECOGNITION IN BIONIC PROSTHESIS
Authors: Yarygin A. A. , Aytbaev B. H. , Kanyshev A. Yu. , Alekseeva E. A.
Published: June 2019

For sterling application of scientific and engineered achievements in field of bionic prosthesis it’s required to provide comfortable  and natural human‑prosthesis interface for an end‑user. In this article we are looking into ways and methods of analysis of the  signal collected through electromyography activity of muscles on the skin surface. Such signal is nonstationary and unstable  by  its  nature,  dependent  on  various  factors.  sEMG  based  interface  has  several  unsolved  problem  at  the  moment,  such  as  insufficient accuracy of recognition and noticeable delay caused by signal recognition and processing. Article is dedicated to  application of deep machine learning required to provide decent recognition of electromyography signals. In the course of the  research hardware was developed to register muscle activity. Data collecting system and algorithms of gesture recognition have  been designed as well. In conclusion decent results were achieved by using convolutional neural network, with two‑dimensional input, since data stream has obvious translational orientation. In the future, modification of neural network architecture, learning  algorithms and experiments with structure of data are planned.
EXAMPLE OF ADAPTIVE STRATEGY OF PROJECTS’ IMPLEMENTATION
Authors: Orlov I. V. , Pryadko S. A.
Published: June 2019

Example of fulfillment of two projects by enterprise on determined time horizon is considered in the article. It is necessary to  estimate average possible income from the work on projects as well as to try to outwork strategy in cases of different situations,  which may arise while work. Link to algorithm is shown described earlier in other article as well as its short description. The  algorithm uses elements of dynamic programming of Markov’s chains. It is suggested to find probabilities of changes from one  condition into another with use of rework of experts’ judgments. It is told about possible situations in the process of projects’  implementation,  about  possible  income,  about  possible  expenses.  Methods  of  evaluation  of  events’  probability  while  works’  fulfillment and relevant methods of calculation of average income are shown.