bluuebunny/crossref_metadata_2025 huggingface dataset:
Using LINE as a Platform for Encouraging Students’ Learning and Participation
Authors: Ekahitanond Visara
Published: October 2024

Using online discussion forums and peer-to peer interactive learning currently becomes a common instructional proposition. Such social discourse is educationally adopted to enhance learning and through ideas interchanged in an online setting. The aim of this study was to investigate the use of LINE as an instructional tool complementing language practice to express opinions in an EFL course. In order to examine factors related to student learning performance in the online discussion activity, data were collected from learning score, quantity of interaction, as well as attitude from 83 students. Frequency, mean, and correlation coefficients were employed to analyze. The findings revealed students’ positive attitude toward the online activity, with the highest mean score indicating an enjoyable learning environment. The students’ learning outcome showed positive correlation with frequency of their interaction; however, it was disassociated with their attitude toward the assigned online task. Furthermore, students’ engagement in the learning disclosed no relation with their attitude toward the online educational experience. The finding of the study can be beneficial for online activity course designs in the future. Apparently, student participation is considered a vital variable; thus, motivation strategies are to be carefully planned to facilitate effective online learning.
An Incremental Model for Cloud Adoption: Based on a Study of Regional Organizations
Authors: Erturk Emre
Published: October 2024

Many organizations that use cloud computing services intend to increase this commitment. A survey was distributed to organizations in Hawke’s Bay, New Zealand to understand their adoption of cloud solutions, in comparison with global trends and practices. The survey also included questions on the benefits and challenges, and which delivery model(s) they have adopted and are planning to adopt. One aim is to contribute to the cloud computing literature and build on the existing adoption models. This study also highlights additional aspects applicable to various organizations (small, medium, large and regional). Finally, recommendations are provided for related future research projects.
EPIDEMIA DE HIV/AIDS EM 2022: UM DESCRITIVO SOBRE O CONHECIMENTO DE UNIVERSITÁRIOS
Authors: Fernandes Ferreira Lucilei , Fálico Faria Mayara , Nuevo Gatti Márcia Aparecida
Published: October 2024

Objetivo: aferir o nível de conhecimento de universitários sobre HIV/AIDS. Método: estudo exploratório, quantitativo-descritivo, com a população de universitários utilizado um questionário online formulado no Google Forms, contendo 31 perguntas sobre os saberes envolvendo HIV/AIDS. Resultados: amostra final foi constituída por 127 questionários analisados, sendo a população predominantemente do sexo feminino (73,2%), cor branca (85,8%), solteiros/separação legal (54,4%), das áreas de biológicas e saúde (62,2%), com a faixa etária entre 20 a 25 anos, que possuem vida sexual ativa (81,9%), fazem uso de preservativos nas relações sexuais (63%) e que não tiveram alguma IST (83,5%). Discussão e Conclusão: grande parte dos participantes têm conhecimento sobre as formas de transmissão e proteção, mas ainda assim, notou-se que existem dúvidas pontuais, não havendo associação desses conhecimentos com comportamentos sexuais seguros, sendo necessária a construção de novas metodologias sobre educação sexual.
Palavras-chave: Síndrome da Imunodeficiência Adquirida (HIV/AIDS). Universitários. Conhecimento. Educação em Saúde. Saúde Sexual.
Knowledge, skills, and household food preparation practices in the north of Pretoria - Gauteng province, South Africa
Authors:   University of Mpumalanga, Ncube LJ , Manafe M ,   Sefako Makgatho Health Sciences University, Gordon RE ,   Sefako Makgatho Health Sciences University
Published: October 2024

The food preparation method is one of the critical food security dimensions. Food may be available in a household. But still, the preparation method used for cooking food items may be detrimental to nutrient intake if the person responsible does not have appropriate cooking skills. Therefore, this study aims to assess the knowledge, skills, and household food preparation practices in the North of Tshwane, Gauteng Province to develop relevant intervention strategies to improve the community’s cooking skills. A quantitative study design was used. Data was collected from 490 households using an interviewer-administered questionnaire. Descriptive statistics were analyzed using STATA 13.1. A Pearson chi-square was used to test for association between demographic variables, and the knowledge, skills, and household food preparation practices. Most households (64%) cook daily, 58% cook one main meal daily, 45% never eat food not prepared in a household, and 48% do not eat meals prepared away from home and do not opt to eat any meal out. Most households (51%) reported that they have food-cooking skills. Most households (65%) indicated that they use the boiling cooking method when cooking vegetables, 19% indicated that they use other methods, and 8% indicated that they use the frying method. There was an association between age, and how many main meals the households prepared at home (P-value = 0.013); age, and how often the households ate out (P-value = 0.026). An association was found between adults employed in a household, and how the household acquired cooking skills (P-value = 0.029); adults employed in a household and the cooking methods normally used by households when cooking meat (P-value = 0.050). Although most households indicated that they have cooking skills, there is a slight difference between them, and those who indicated that they don’t, as most households indicated they use the boiling method for cooking vegetables. This denotes a cooking skills gap, which demands intervention. Also, cooking skills should be improved to reduce food wastage thus addressing household food security. Key words: Food security, households, home-cooking, cooking skills, cooking practices
Risk factors of anemia among children aged 6-59 months in Madagascar
Authors:   Korea University, Kim Y , Choi Y ,   Johns Hopkins School of Public Health, Kim C ,   Korea University, Seo E ,   Treasure International, Kang Y ,   Johns Hopkins School of Public Health
Published: October 2024

While child anemia remains an uncontrolled health issue in developing and underdeveloped countries, the public health burden of child anemia is high in Madagascar. Using cross-sectional data from Madagascar Demographic and Health Survey 2021 (Madagascar DHS 2021), this study aims to examine the prevalence and risk factors of child anemia by region and socioeconomic status in the country. A total of 5,048 children aged 6-59 months with hemoglobin (Hb) concentration data were used for the study. First, the associations between child anemia (Hb< 11.0g/dl) and the household, parental, and child characteristics were tested by univariate logistic regression analysis. Variables with a p-value <0.05 in the univariate were included in the multivariate regression analysis, and sub-group analysis was conducted for six provinces. A heatmap was provided to visualize the distribution of common risk factors for the child anemia across six provinces. The prevalence of child anemia was 47 %. Child anemia was negatively associated with older age, and positively associated with maternal anemia in a dose-response manner, maternal younger age (<25 years old), underweight (BMI<18.5), low education level, history of fever or diarrhea in the past two weeks and high birth order (5th or higher, compared to the 1st). There was a regional variation in anemia (3.8% to 56.3%) with a higher prevalence in the Southern provinces compared to Antananarivo province, the capital area. The age of the child and the maternal anemia status consistently determined child anemia status in all six provinces, with certain region-specific factors such as female child, poor wealth, maternal obesity, women’s empowerment, and iron supplementation. The prevalence of child anemia across Madagascar was found to be closely linked to both the age of the child and the maternal status, including health related, and socioeconomic conditions, which need to be more comprehensively examined. Further research is required to explore the pathways by which child anemia is related to maternal anemia and varies by regional location is required. Interventions targeting both anemic mother-child pairs, vulnerable populations, and young children are recommended to strengthen national nutrition programs in the country. Key words: Anemia prevention, anemia control, Madagascar, child health, public health
Designing and validating an effective iconography for the dissemination of food-based dietary guidelines in Peru: A qualitative study
Authors:   National Institute of Health, Lázaro-Serrano ML , Domínguez-Curi CH ,   National Institute of Health, Ríos-Castillo I ,   University of Panama
Published: October 2024

Changes in dietary patterns towards Western diets, along with unhealthy lifestyles, are causing a rapid increase in the rates of overweight, obesity, and non-communicable chronic diseases in the Peruvian population. Food-based dietary guidelines (FBDG) are supportive tools for public policies aimed at promoting healthier eating habits. This study aimed to present the process of designing and validating an iconography for the Peru FBDG. The design process involved an extensive review of dietary iconography in various countries of the LAC region. In accordance with the specific context of Peru, the decision was made to incorporate local elements into the iconography. Four image proposals were initially designed and subsequently subjected to expert validation. From these, two proposals were selected for population validation through focus groups. The validation process focused on qualitative evaluation criteria, including understanding, attraction, involvement, acceptance, and induction to action. The resulting final iconography consists of two concentric circles. The central circle represents the seven food groups distributed proportionally, while the outer circle signifies healthy lifestyles, encompassing physical activity, commensality, and daily water consumption, portrayed in vibrant colors. Surrounding the circles are icons representing ultra-processed foods depicted in black octagons. Additionally, icons for added sugar and salt are placed outside the circles, serving as prominent warnings to reduce their consumption, as recommended during the validation process. This study successfully developed an iconographic representation that fulfills both technical and population-level validation criteria. The incorporation of participants' contributions and recommendations further enhanced its efficacy. The validated iconography not only serves as an educational and awareness tool but also offers practical guidance for individuals to adopt healthier dietary practices and lifestyles. In conclusion, the FBDG iconography effectively communicated the importance of natural foods over ultra-processed ones, along with emphasizing healthy eating habits, as understood and embraced by focus group participants. The attraction and comprehension of the FBDG iconography looks promising for its implementation, suggesting improvements in the health and nutritional well-being of individuals of two years and above. Key words: Iconography, dietary guidelines, food and nutrition education, healthy lifestyle, Peru dietary guidelines
The effect of polyherbal containing Tamarindus indica and Murraya paniculata leaf extract on triglyceride level using a rat model of hypertriglyceridemia
Authors:   Universitas Gadjah Mada, Wiyono T , Sholikhah EN ,   Universitas Gadjah Mada, Pratiwi WR ,   Universitas Gadjah Mada
Published: October 2024

The current anti-hypertriglyceridemia (HTG) medications still have side effects such as myopathy, rhabdomyolysis, liver damage, and insulin resistance. The development and discovery of new, safer agents to treat hypertriglyceridemia is urgently needed. The leaves of Murraya paniculata have been empirically used for lowering lipids. Meanwhile, Tamarindus indica leaves are reported to contain high antioxidants and anti-diabetic activity. This study was conducted to evaluate the combination effect of leaf extracts from Tamarindus indica and Murraya paniculata to treat hypertriglyceridemia in animal models and to predict the optimum ratio. Hypertriglyceridemic Wistar rats were developed by feeding the high fat-sucrose diet for 75 days. The combination of T. indica extract (TIE) and M. paniculata extract (MPE) was made following the Simplex Lattice Design ranging from 50:350 to 350:50, producing denoted ratios TIE:MPE: (i) 50:350, (ii) 125:275, (iii) 200:200, (iv) 275:125, and (v) 350:50. The extract was given to hyperlipidemic animals orally once per day for 14 days at a dose of 400 mg/kgBW. Prior to the in vivo assay, both extracts were analyzed for their phytochemical content (mineral, phenol and flavonoid content) and water content. The result of lipid profile measurements showed that the combination of 350:50 mg/kgBW (TIE:MPE) gave the strongest effect in lowering triglyceride (p<0.05). As the composition of the TIE extract increased, the TG-lowering effect appeared to strengthen and the body weight gain of rats also decreased in a dose dependent manner. The liver protective activity was observed in all combinations based on hepatic catalase and malondialdehyde measurement. Administration of the combined extract with a high proportion of TIE tends to provide better enhancement of muscle lipoprotein lipase (LPL) activity. In conclusion, it was proven that the combination of Tamarindus indica and Murraya paniculata leaf extracts significantly reduced triglycerides level in animal models. The optimum effect was achieved at a ratio of 350:50 mg/kgBW (TIE:MPE). Finally, purification of extract from primary fat components is suggested for further research. Key words: anti-hypertriglyceridemia, Tamarindus indica, Murraya paniculata, leaf extract, polyherbal, Simplex-Lattice-Design, obesity, animal-model
I. - Symposium sur la variabilité, la reproduction et la conservation des arbres des forêts tropicales
Authors: Grison François , Malagnoux Michel
Published: October 2024

Pas de résumé
Epilepsy Secondary to Occipital Cobblestone Malformation in an Adult Patient with Merosin-Deficient Congenital Muscular Dystrophy Type 1A
Authors: Schön Miguel , Bentes Carla , Morgado Carlos , Oliveira Santos Miguel
Published: October 2024

N/a.
QUALITY OF LIFE THE ELDERLY AND AVAILING OF NON-FOOD-BASED NATIONAL SOCIAL ASSISTANCE SCHEMES IN INDIA: A CROSS-SECTIONAL STUDY
Authors: Lo Sourav , Pramanik Rama , Biswas Daliya
Published: October 2024

Background: Health and quality of life (QOL) are crucial constituents. In providing social safety for older people, the weakening social support system and rising burdens are having huge impact. Purpose: To assess the QOL of old age people and their relationship with availing of non-food-based social assistance schemes. Methods: This was a descriptive community-based study which was conducted in urban slums of Bankura district, West Bengal among all individuals aged ≥60 years fulfilling inclusion and exclusion criteria. WHOQOL-BREF questionnaire was used for assessing QOL. Results: A total of 107 participants were recruited for the study. Most common morbidities were hypertension, diabetes mellitus, chronic bronchitis, etc. The majority (80.5%) of participants were receiving non-food-based NSAS for less than 10 years. Overall QOL was ‘Good’ in 69.2% of study subjects. Most of the elderly had ‘Good’ QOL in Physical, Psychological, Social, and Environment domains. Participants availing non-food-based NSAS had good physical, social, environmental health of QOL and overall QOL. Conclusion: Despite good QOL among the elderly, appropriate and relevant health indicators need to be developed.
Integration of Blockchain Technology into the Internet of Things (Overview)
Authors: Serebriakov Roman , Tkachenko Valentyna , Klymenko Iryna
Published: October 2024

One of the modern trends in the development of information and communication technologies that have evolved into the Internet of Things (IoT) paradigm is the progressive idea of using blockchain technology in IoT. This trend is described in a large number of modern literature sources, which point out the significant advantages of using blockchain, primarily related to decentralization, immutability, transparency and security. This allows us to conclude that the implementation of blockchain technology in IoT information and communication systems is highly relevant. However, the authors of different studies describe significant problems, including the problem of scalability of the blockchain itself, as well as the problems of energy efficiency and limited resources in IoT devices. Due to these problems, the implementation of blockchain technology in the Internet of Things is becoming a challenge and determines the relevance and feasibility of researching this topic and finding effective solutions related to the integration of two very powerful technologies in modern information and communication systems.
The article presents an analytical overview of the issues of integrating blockchain technology into IoT, in particular, the use of the Proof-of-Work (PoW) consensus algorithm in IoT and the use of alternative blockchain protocols, including IOTA, Ethereum Light Client and Litecoin, which allow increasing the efficiency of performing tasks in IoT infrastructure, taking into account the limited resources of devices; existing problems and implementation methods, such as the use of light clients and proxy servers. The article also considers the feasibility of using a full blockchain node on IoT devices and ways to increase system efficiency by pre-processing data before sending it to the blockchain network. The article also highlights the problem of insufficient implementation of blockchain technology in various spheres of human life, as well as the search for the reasons for this problem.
The results of the analytical review make it possible to substantiate the purpose and advantages of integrating blockchain technology into the Internet of Things, as well as to summarize the main issues and substantiate a number of tasks for relevant and progressive scientific research in the field of modern information and communication systems.
Analysis of the Leading and Non-Leading Sectors of South Sulawesi's Revenue Potential
Authors: Topadda M Ilham , I Ketut Patra  , Rismawati
Published: October 2024

This study aims to identify leading sectors and non leading sectors and analyze the potential of non leading sectors in South Sulawesi. This research method uses Location Quotient (LQ) to measure sector concentration relative to the national level and Klassen Typology to classify economic sectors based on growth dynamics and regional economic contribution. This research utilizes data from the Central Bureau of Statistics (BPS) of Indonesia and South Sulawesi covering the years 2019-2023. The results show that sectors such as agriculture, forestry, fisheries, construction, wholesale and retail trade, financial and insurance services, education services, and health services and social activities are leading sectors with significant comparative advantages. In contrast, sectors such as mining, manufacturing, transportation, warehousing, accommodation and food services, and information and communication have the potential to be further developed with appropriate investment and supportive policies. Strategies to develop non-lead sectors include increased investment in technology and infrastructure, human resource development, and the provision of strong policy support. These developments are critical to diversifying the economy and achieving sustainable growth in South Sulawesi.
The Influence of Emotional Intelligence and Learning Environment On University Student Performance
Authors: Annisa Savira
Published: October 2024

The purpose of this study is to determine and analyze the influence of emotional intelligence (X1) and learning environment (X2), both simultaneously and partially, on the performance of students at the Faculty of Economics and Business, Tadulako University. This type of research is quantitative research. This research sample consists of 87 active students at Tadulako University's Faculty of Economics and Business. The analytical tool used is multiple linear regression analysis. Based on the results of the multiple linear regression analysis, it was found that the variables emotional intelligence (X1) and learning environment (X2) simultaneously have a significant effect on the performance of students at the Faculty of Economics and Business, Tadulako University, with a significant value of 0.000 below < 0.05. From the results of the partial testing (t-test), it was found that the emotional intelligence variable (X1) has a significant influence with a significance value of 0.008 > 0.05. The Learning Environment (X2) with a significance value of 0.000 < 0.05, which means there is a significant influence on student performance.
The The Influence of Interpersonal Communication, Compensation, and Work Environment on Employee Job Satisfaction at PT Rajawali Nusantara Indonesia (Persero)
Authors: Supardi Aditya Darmawan
Published: October 2024

This research aims to describe the relationship of interpersonal communication, compensation, and work environment on employee job satisfaction. The purpose of this research is to explain the influence of interpersonal communication, compensation, and work environment on employee job satisfaction both partially or simultaneously at PT Rajawali Nusantara Indonesia (Persero). The population in this research is all employees of PT Rajawali Nusantara Indonesia (Persero), totaling 267 employees. The sample size in this study consist of 160 employee respondents with a purposive sampling. This research uses a quantitative approach by collecting data through Google Form questionnaires and observation. The analytical method used is the descriptive analysis model and the multiple linear regression analysis model using SPSS version 26 software. The results of this study show that interpersonal communication, compensation, and work environment partially have a significant influence on job satisfaction. Furthermore, interpersonal communication, compensation, and work environment together (simultaneously) have a significant influence on job satisfaction.
Analysis Of Archives Digitalization System Management In Lldikti Region Iii Jakarta
Authors: Baringbing Rizki , Marsofiyati  , Maulida Ervina
Published: October 2024

This research used a qualitative descriptive method which was carried out with the
aim of finding out more about the management of the archive digitization system at
LLDikti Region III Jakarta. Data collection techniques use observation, interviews, and documentation and are obtained from previous research, articles, books, andw ebsites related to research on archival digitization system management.
Optimizing Marketing Management at BUMDes Tridadi Makmur and BUMDes Mekaring Pono Potorono in Increasing Revenue
Authors: Elrahman Fitriyatunnisa , Suhud Usep , Wahyu Handaru Agung
Published: October 2024

Village-Owned Enterprises, hereinafter referred to as BUM Des, are village businesses formed/established by the Village Government whose capital ownership and management are carried out by the Village Government and the community. The village business is a type of business in the form of village economic services such as service businesses, distribution of nine basic materials, trade in agricultural products, as well as industry and folk crafts. Village-Owned Enterprises will be better if in the village there are community business units that are the economic ties of the community that are managed in a perceived and accommodated manner to increase community income and original village income (Lutfia, 2021).
One of the economic institutions operating in Rural, BUM DESa must have a difference with economic institutions in general. This is intended for the existence and performance of BUM Desa able to make a significant contribution to improving the welfare of villagers. According to Law Number 6 of 2014, BUM Desa is a business entity whose capital is wholly or most of the capital owned by the Village through direct participation derived from the Village's wealth which is separated to manage assets, services, and businesses others for as much as possible the welfare of the village community (Bappenas Working Papers, 2018).
Assessment of the Prevalence of Leptospiroses and Hemorrhagic Fever with Renal Syndrome in the Leningrad Region
Authors: Riabiko E. G. , Grechishkina D. I. , Baimova R. R. , Karmokov I. A. , Buts L. V. , Khalilov E. S. , Lyzenko I. S. , Tokarevich N. K.
Published: October 2024

The aim of the study was to determine the prevalence of leptospiroses and hemorrhagic fever with renal syndrome (HFRS) among residents of some administrative districts of the Leningrad Region. Materials and methods. 958 blood serum samples of conventionally healthy individuals living in the following territories of the Leningrad Region: Boksitogorsky, Volosovsky, Vyborgsky, Kingiseppsky, Lodeynopolsky, Luzhsky, Podporozhsky, Priozersky, Slantsevsky and Tikhvinsky districts – were analyzed by enzyme immunoassay. The retrospective epidemiological analysis of the incidence of leptospirosis and HFRS in the population of the Leningrad Region in 2011–2020 was carried out based on the data from the Rospotrebnadzor Administration and Forms No. 2 “Information on infectious and parasitic diseases”. Results and discussion. All in all, 54 cases of leptospirosis and 104 cases of HFRS were registered in the Leningrad Region in 2011–2020. The long-term average annual incidence rate (LTAAIR) for leptospirosis was 0.32. In Boksitogorsky, Vyborgsky, Lodeynopolsky, Podporozhsky and Slantsevsky districts, cases of leptospirosis were not recorded, but IgG-antibodies to Leptospira interrogans were detected in residents of those areas. The LTAAIR for HFRS was 0.63. There are no registered cases of HFRS in the Kingiseppsky, Podporozhsky, and Slantsevsky districts. IgG-antibodies to Orthohantavirus were detected in volunteers in all surveyed areas. The detection of specific antibodies in the blood sera of conventionally healthy people living in the Leningrad Region indicates contact of the population with pathogens of leptospirosis and HFRS. The lack of registered morbidity in some areas is probably due to their hypo-diagnosis, as evidenced by the detection of antibodies to the pathogens of these infections in people living in the corresponding territories.
Comparative Analysis of the Legal Framework of the Republic of Tajikistan against the Provisions of the International Health Regulations (2005)
Authors: Sufiev A. Z. , Nazarova O. D. , Dzhafarov N. Dzh. , Anvarova G. B.
Published: October 2024

The aim of the work was to conduct a comparative analysis of the existing national legal framework against the provisions of the International Health Regulations (IHR) (2005). The main issues of harmonization of the existing documentation in accordance with modern international requirements have been identified. A number of gaps and inconsistencies in the legislative acts that do not fully comply with the requirements of international legal acts recognized by the Republic of Tajikistan are revealed. Proposals for optimization and improvement of the national legal framework and regulatory documents, as well as for adaptation to the requirements of the IHR (2005) are presented.
Peculiarities of Vesiculation in Virulent and Avirulent LPS-Defective Strains of Francisella tularensis of Various Subspecies
Authors: Aronova N. V. , Pavlovich N. V. , Meloyan M. G. , Tsimbalistova M. V. , Noskov A. K.
Published: October 2024

The aim of the study was to compare outer membrane vesicles (OMVs) and their composition in virulent and avirulent (LPS-defective) strains of Fracisella tularensis of various subspecies. Materials and methods. The vesiculation process in F. tularensis bacteria was studied using transmission electron microscopy. OMVs preparations were obtained and characterized by their composition using immunological methods: antibody neutralization test, immunochromatographic analysis, dot and immunoblotting. Results and discussion. It has been found that all natural virulent strains with the S type lipopolysaccharide (LPS) are able to produce two forms of vesicles – spherical and tubular (“tubes”), specific for F. tularensis. OMVs formation has not been registered in avirulent LPS-defective strains. It is revealed that vesicles of strains of various subspecies show their own individual morphological features. The tubes of F. tularensis subsp. mediasiatica are larger in size as compared to those of the subsp. holarctica strain. This is probably the reason why vesicle preparations from F. tularensis subsp. mediasiatica obtained using filters with a diameter of pores being 0.22 μm contained a significantly reduced number of tubular forms. A method of disinfection of bacterial suspensions using gentamycine, which does not affect the morphology and antigenic activity of vesicles, is proposed. A comparative study of several series of concentrated OMVs preparations obtained from different strains has revealed that all samples had antigenic activity in the precipitation Ouchterlony test, antibody neutralization test, immunochromatografic assay, dot-blot and immunoblotting. Immunodominant antigen – LPS and several major antigenic proteins have been detected in the preparations. Differences in the composition of vesicle proteins in the strains of various F. tularensis subspecies have been identified.
Production and Characterization of Immune Ascitic Fluids to Vibrio cholerae R-Variant Strains
Authors: Evdokimova V. V. , Alekseeva L. P. , Yakusheva O. A. , Levchenkо D. A. , Rengach M. V.
Published: October 2024

The aim of the work was to obtain immune ascitic fluids (IAF) of mice to whole cells of R-variant cholera vibrios and to evaluate the possibility of their use for detection and characterization of atypical cholera vibrios. Materials and methods. A cycle of immunization of nonlinear white mice was performed. It included four injections of antigen with and without adjuvant, induction of ascitic fluid accumulation through intraperitoneal inoculation of murine myeloma cells. Experimental IAFs were studied in serologic and immunologic reactions on a set of strains of R-variant Vibrio cholerae, V. cholerae nonO1/nonO139, V. cholerae O1 and heterologous microorganisms. Results and discussion. The obtained IAFs are notable for high antibody titers in indirect enzyme immunoassay (up to 1:640000), and agglutinate atypical cholera vibrios at dilutions from 1:8 to 1:32 in slide-agglutination reaction. Cross-reactions were found in the three groups of V. cholerae strains studied, indicating the presence of similar antigens. Based on the results of electrophoretic separation and immunoblotting of cell lysates of the strains, the presence of common major proteins in the region of 55–60 and 25 kDa was established. Evident differences were observed for several minor proteins in the 30–55 kDa region, in particular, they were absent in the typical strains. It is also shown that experimental IAFs contain antibodies to epitopes of the core part of LPS and surface proteins, most of them being common to the studied groups of cholera vibrios. The obtained data allow us to draw the following conclusions: the possibility of detecting a larger number of V. cholerae R-variants is increased if the ELISA kit to R-vibrios is used; the use of ELISA method is preferable to the slide-agglutination reaction for serologic analysis of atypical strains. Combining IAFs in the form of a single preparation seems promising, as it allows for characterizing the spectrum of surface antigenic determinants of altered strains and expanding the possibilities of their detection.
Prevalence of Anxiety and Depression in COVID-19 Patients and Frontline Healthcare Workers
Authors:   Department of Internal Medicine, Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan., Khan Faheem , Babar Zainab ,   Department of Pharmacy, Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan., Imtiaz Saira ,   Department of Research, Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan., Khalid Abdullah ,   Department of Hepatobiliary & Pancreatic Surgery, Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan.
Published: October 2024

Abstract: Background: During global health crises such as the COVID-19 pandemic, understanding the psychological impact on both patients and healthcare workers is crucial for effective public health response and support strategies. Objectives: To assess anxiety and depression prevalence among COVID-19 patients and healthcare workers in Pakistan, utilizing the Aga Khan University Anxiety and Depression Scale. Materials and Methods: A cross-sectional survey from 20th May 2020 to 25th August 2020, using a 15-item structured questionnaire was conducted on patients diagnosed with COVID-19 and healthcare workers at the Pakistan Kidney and Liver Institute & Research Center, Lahore. The Aga Khan University Anxiety and Depression Scale - Short Form (AKUADS-SF) was employed to assess the levels of anxiety and depression among the participants. Data were analyzed using descriptive statistics, chi-square tests, and logistic regression to identify significant predictors of anxiety and depression. Result: Of 183 participants, 55% were healthcare workers and 44.8% were patients. Preliminary findings showed 37.6% of healthcare workers had anxiety and depressive symptoms. Significant predictors among healthcare workers included family members with psychiatric disorders, family members affected by COVID-19, and a history of psychiatric disorders. Among patients, 13.4% had positive scores on the AKUADS-SF, with significant predictors being marital status (single), affected family members, smoking, and addiction. Conclusion: The study identified significant anxiety and depression among healthcare workers and patients during COVID-19. Predictors for healthcare workers included family psychiatric issues and personal history, while patients’ predictors were marital status, affected family members, smoking, and addiction. This underscores the need for targeted psychological support.
Model Pengembangan Pelaksanaan Uji Kompetensi Berbasis Digital dalam Peningkatan Kualitas LSP di Perguruan Tinggi
Authors: Prastyana Brahmana Rangga , Prasetyo Aji , Putra Very Ferdiansyah Eka
Published: October 2024

The improvement of student competency in the Higher Education environment is carried out by the Professional Certification Institute (LSP), namely through competency test activities in the competency certification scheme it has. As a form of improving the quality of LSP, the development of digital-based competencies needs to be carried out so that it can be an alternative in implementing competency tests that are still guided by applicable regulations, upholding the principles of competency testing and are more effective and efficient. The purpose of this study is to develop a model for implementing competency test activities for all certification schemes in LSP, starting from registration to the pre-assessment stage. This research is a type of development research with a research and development (R and D) model. The procedure in development research uses steps including the stages of analysis, design, development, implementation, and evaluation. The subjects in this study were LSP implementers in Higher Education, in this case LSP P1 Universitas PGRI Adi Buana Surabaya. This study uses expert validation tests related to the content and products of the development. The results of a series of research activities based on trial evaluations are known to obtain an average score of eligibility of 3.81 with a maximum scale of 4 in the very good category. From the evaluation results, improvements are needed in the design aspects, namely the type of writing, the appearance of the background and the addition of videos as a guide for prospective assessors in this case students of Universitas PGRI Adi Buana Surabaya.
Automated Borehole Image Interpretation Using Computer Vision and Deep Learning
Authors: Gharieb Amr , Ibrahim Ahmed Farid , Gabry Mohamed Adel , Elsawy Mohamed , Algarhy Ahmed , Darraj Nihal
Published: October 2024

Reservoir characterization is critical for successful oil and gas exploration, heavily reliant on detailed formation analysis from formation microimager (FMI) logs. However, interpreting these complex logs is time-consuming, subjective, and requires expert-level knowledge. This study addresses this challenge by proposing a novel approach that integrates computer vision (CV) and deep learning (DL) for automated and real-time interpretation of FMI logs.

Our methodology leverages CV and DL techniques for automated feature extraction and classification from FMI data. A comprehensive training data set encompassing more than 2,500 images is utilized to train the DL model, enabling the identification of more than 50 distinct geological features, including bedding planes, fractures, and mineral variations. In addition, the study explores the creation of local stress maps from drilling-induced fractures to determine the present-day maximum horizontal stress (SHmax) orientation, crucial for optimizing wellbore stability and hydraulic fracturing strategies.

This research presents a groundbreaking advancement in reservoir characterization through the synergy of automated FMI interpretation, CV, and DL. The developed model exhibits exceptional accuracy in geological feature classification, significantly surpassing traditional, human-centric interpretations. For instance, the model achieves a remarkable 92% accuracy in classifying ore than 50 geological features, demonstrably outperforming conventional methods. Furthermore, the developed model was applied to actual field cases to predict the stress field. The model was able to accurately predict the minimum horizontal stress (Shmin) and SHmax based on FMI logs, and the results were used to refine the geomechanical modeling and optimize hydraulic fracture orientation for enhanced hydrocarbon recovery.

This work establishes a new benchmark for applying artificial intelligence in subsurface analysis, paving the way for future advancements in reservoir management and geomechanics. The implications are far-reaching, offering greater precision in geological interpretations, improved decision-making for production strategies, and ultimately, a more sustainable approach to hydrocarbon extraction. By automating tedious and subjective tasks, this approach not only reduces reliance on experts but also frees up valuable time for more strategic tasks. The ability to extract critical geological information with such accuracy from complex FMI logs translates to significant improvements in reservoir characterization and production efficiency.
Effects of immersive virtual environments on the performance of motor imagery brain-computer interfaces: A study on virtual environment, gamification and age relations.
Authors: Baspinar Ulvi , Tastan Yahya , Hamurcu Ahmet , Bal Abdullah , Okay Burcu Bulut , Bakır Barkın , Demiroğlu Murat , Topuz Vedat , Erguzel Türker Tekin , Acar Gonul
Published: October 2024

Objective: This study aims to investigate the influence of immersive virtual reality environments and gamification on the classification of motor imaginary (MI) signals and the associated increase in energy in the motor cortex region considering differences across age groups. Approach: Two immersive virtual environments, categorized as indoor and outdoor, were chosen, each encompassing gamified and non-gamified scenarios. Investigations into Event-Related Desynchronization (ERD) data were performed to determine the presence of significant discrepancies in ERD levels among varying age groups and to assess if Fully Immersive Virtual Reality (FIVR) environments prompted marked enhancements in energy levels. Main results: The preliminary analysis revealed a significant difference in cortical energy increase between gamified and non-gamified environments in the 32-43 age group (Group II). The study also explored the impact of environmental factors on MI signal classification using four deep learning algorithms. The Recurrent Neural Network (RNN) classifier exhibited the highest performance, with an average accuracy of 86.83%. Signals recorded indoors showed higher average classification performance, with a significant difference observed among age groups. The 21-24 age group (Group I) performed better in non-gamified environments (88.8%), whereas Group II performed well indoors, particularly in the gamified scenario (93.6%). Significance: The study is significant because it demonstrates how different immersive virtual environments and gamification affect performance in imaginary motor signal classification and cortical energy changes across age groups. This research holds importance as it showcases the impact of design variations within immersive virtual environments on enhancing the efficacy of brain-computer interface-driven systems. It underscores the necessity for further comprehensive investigations in this field.
Efficient removal of Sb(III) from aqueous solution using recyclable magnetic metal-organic frameworks Fe3O4@MIL-100 and Fe3O4@MIL-101
Authors: Song Xinyu , Zeng Zhen , Wang Shuo , Li Jun , Liang Yingqi , Rao Wenhao , Li Kun , Wang Zhenxing , Huang Lei
Published: October 2024

Antimony (Sb) pollution is becoming increasingly serious. The pollution of water bodies containing antimony poses a great threat to the ecological environment and human health. In this study, two types of magnetic metal-organic frameworks(MOFs), namely Fe3O4@MIL-100(Fe) and Fe3O4@MIL-101(Fe), were prepared to investigate the removal effect on antimony (Sb). The influence of factors such as pH value and initial concentration on the adsorption effect was studied in detail. Compared to Fe3O4@MIL-100(Fe), the study found that the adsorption reaction rate of Fe3O4@MIL-101(Fe) was much higher than the former, reaching equilibrium after 10 minutes of addition. The fitting results conformed to the chemical adsorption behavior of the pseudo-second-order kinetic model. Mechanism characteristic analysis revealed that the Fe-O-Sb formed by Fe ions in the metal clusters and Sb (III) was the main adsorption mechanism. In addition, vibrating sample magnetometer (VSM) and adsorption tests showed that the material still possesses magnetism after adsorption, and the adsorption capacity remains basically unchanged after three cycles. These results indicated that the two magnetic Fe-based MOFs were effective and recyclable adsorbents, providing a new approach to the design of regenerative adsorbent materials.
Forecasting the Fate of Forest Dwellers: Comparative Modeling of Barking Deer Habitats Against Climatic and Anthropogenic Shifts in the Western, Central, and Eastern Himalayas
Authors: Sharma Chandra Maya , Bhattacharya Saurav , Singh Hemant , Dutta Ritam , Joshi Bheem Dutt , Thakur Mukesh , Sharma Lalit Kumar
Published: October 2024

Barking deer (Muntiacus vaginalisBoddaert, 1785), or Northern Red Muntjac, is a solitary forest-dwelling cervid distributed from eastern Pakistan to Indonesia, including Southeast Asia. Despite its wide range, habitat assessments for the species are limited. This study models the distribution of Barking deer in the Indian Himalayan Region (IHR) using primary data (camera traps, sign surveys) and secondary data (literature, GBIF). Bioclimatic, land use, topographic, and anthropogenic variables were used to predict current and future habitat suitability for 2050 and 2090 under SSP2.6 and SSP8.5 emission scenarios.
We analysed three biogeographic provinces of the IHR: Western Himalaya, Central Himalaya, and Eastern Himalaya. The estimated current suitable habitat is 7,363 km² in the Eastern Himalaya, 1,932 km² in the Central Himalaya and 30,573 km² in the Western Himalaya. Future projections indicate a decrease in suitable habitat in the Eastern and Central Himalayas under combined climate and land use change scenarios. Conversely, the Western Himalaya shows an increase in suitable habitat. Key variables influencing distribution include temperature and precipitation patterns, forest cover, and human impact indices.
The landscape metrics and fragmentation analysis revealed significant differences across the provinces. The number of suitable habitat patches in the Western Himalaya is currently estimated at 347, with an increase in patch size projected under future scenarios. In contrast, the Central and Eastern Himalayas have 33 and 54 patches, respectively, with future projections indicating a decline in both number and size of patches. This fragmentation suggests that Barking deer in these regions may face greater habitat loss and reduced connectivity. Effective conservation planning and habitat management are crucial for sustaining Barking deer populations and the larger ecosystem, including predators that rely on them. The study emphasizes the need for enhanced conservation efforts, particularly in the Eastern and Central Himalayas.
Global Analysis and Control of a Hepatitis B Spread Dynamics Model
Authors: Milongo Gallimard Nzinga , Langa Reval , Mabonzo Delmas Vital , Mongo-Onkouo Arnaud , NDONDO Apollinaire Mboma
Published: October 2024

This study examines the stability of a mathematical model for the dynamics of hepatitis B spread, dividing the population into six compartments. Through qualitative analysis, we determined the basic reproduction number R 0 and investigated its asymptomatic behavior under various conditions, considering both progressive and non-progressive disease scenarios (stability and instability regions). Utilizing existing literature values, numerical simulations were conducted to validate the theoretical findings. The model with biological controls demonstrates that frequent sensitization campaigns throughout the year can help eradicate the disease in the population.
Maturation, conversion and metabolic profile of somatic embryos derived from Klussia odoratissimaMozaff as affected by light spectra ​
Authors: Khosravi Farnoosh , Rafiei Fariba , Ebrahimi Morteza , Rabiei Mohammad
Published: October 2024

The present study investigated potential application of somatic embryogenesis (SE) for conservation of Klussia odoratissima Mozaff. As the efficiency of SE greatly varies depending on the culture conditions including light, effects of five light spectrums including a fluorescent light and four types of light - emitting diode (LED) (red, blue, 3red-1blue, and3blue:1red) for an exposure time of a month on the maturation of K.odoratissima were also studied. To better understand the effect of light treatment on conversion of K.odoratissima cultures, two months after treatment, fresh and dry weight and metabolite contents were evaluated. Samples of the same age in situ plant and air-dry plant were also considered for relative comparison. Study of developmental stage of K.odoratissima under in vitro conditions revealed that a combination of 3red:1blue LED provided the highest number of cotyledonary (mature) embryos per callus. Hence, this light treatment was identified as the best treatment for the conversion of somatic embryos in K.odoratissima. Consequently, the highest fresh and dried weights were recorded in the cultures grown under 3blue:1red and blue LED treatment. Phthalide content of in situ plant was significantly greater than other treatments. Interestingly, the phthalide content was significantly higher in tissue culture samples compared to air-dry plants, which suggests tissue culture as an alternative technique for the production of bioactive compound in K.odoratissima. Cultures were incubated in 3blue:1red LED followed by blue LED possessed higher contents of phthalides. Application of LEDs is promising approach in micopropagation of K.odoratissima.