bluuebunny/crossref_metadata_2025 huggingface dataset:
Aflatoxin Exposure from Milk in Rural Kenya and the Contribution to the Risk of Liver Cancer
Authors: Sirma Anima , Makita Kohei , Grace Randolph Delia , Senerwa Daniel , Lindahl Johanna
Published: August 2019

Milk is an important commodity in Kenya; the country has the largest dairy herd and highest per capita milk consumption in East Africa. As such, hazards in milk are of concern. Aflatoxin M1 (AFM1) is a toxic metabolite of aflatoxin B1 (AFB1) excreted in milk by lactating animals after ingesting AFB1-contaminated feeds. This metabolite is injurious to human health, but there is little information on the risk to human health posed by AFM1 in milk in rural Kenya. To fill this gap, a quantitative risk assessment (QRA) applying probabilistic statistical tools to quantify risks was conducted. This assessed the risk of liver cancer posed by AFM1 in milk, assuming 10-fold lower carcinogenicity than AFB1. Data from four agro–ecological zones in Kenya (semi-arid, temperate, sub-humid and humid) were used. We estimated that people were exposed to between 0.3 and 1 ng AFM1 per kg body weight per day through the consumption of milk. The annual incidence rates of cancer attributed to the consumption of AFM1 in milk were 3.5 × 10−3 (95% CI: 3 × 10−3–3.9 × 10−3), 2.9 × 10−3 (95% CI: 2.5 × 10−3–3.3 × 10−3), 1.4 × 10−3 (95% CI: 1.2 × 10−3–1.5 × 10−3) and 2.7 × 10−3 (95% CI: 2.3 × 10−3–3 × 10−3) cancers per 100,000 in adult females, adult males, children 6–18 years old, and in children less than five years old, respectively. Our results show that aflatoxin exposure from milk contributes relatively little to the incidence of liver cancer. Nonetheless, risk managers should take action based on cumulative exposure from all sources of aflatoxins.
Bacteriophage-Based Biotechnological Applications
Authors: Santos Sílvio B. , Azeredo Joana
Published: August 2019

Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools are revealing innovative phage features and enabling new processes that can be further exploited for biotechnological applications in a wide variety of fields. This special issue is a collection of original and review articles focusing on the most recent advances in phage-based biotechnology with applications for human benefit.
Screening of Duck Tembusu Virus NS3 Interacting Host Proteins and Identification of Its Specific Interplay Domains
Authors: Wang Yawen , Zhang Shuai , Tang Yi , Diao Youxiang
Published: August 2019

NS3 protein is a member of the non-structural protein of duck Tembusu virus (DTMUV), which contains three domains, each of which has serine protease, nucleotide triphosphatase, and RNA helicase activities, respectively. It performs a variety of biological functions that are involved in the regulation of the viral life cycle and host immune response. Based on the yeast two-hybrid system, we successfully transformed pGBKT7-NS3 bait plasmid into Y2H Gold, tested it to prove that it has no self-activation and toxicity, and then hybridized it with the prey yeast strain of the duck embryo fibroblast cDNA library for screening. After high-stringency selection, positive alignment with the National Center for Biotechnology Information database revealed nine potential interactive proteins: MGST1, ERCC4, WIF1, WDR75, ACBD3, PRDX1, RPS7, ND5, and LDHA. The most interesting one (PRDX1) was selected to be verified with full-length NS3 protein and its three domains S7/DEXDc/HELICc using yeast regressive verification and GST Pull-Down assay. It denoted that PRDX1 does indeed interact with HELICc domains of NS3. NS3 is involved in the RNA uncoiling process of viral replication, which may cause mitochondrial overload to create oxidative stress (OS) during DTMUV attack. We deduced that the HELICc domain binding partner PRDX1, which regulates the p38/mitogen-activated protein kinase pathway (p38/MAPK) to avert OS, causing apoptosis, making it possible for viruses to escape host immune responses.
Optimized Artificial Neural Networks-Based Methods for Statistical Downscaling of Gridded Precipitation Data
Authors: Salimi Amir Hossein , Masoompour Samakosh Jafar , Sharifi Ehsan , Hassanvand Mohammad Reza , Noori Amir , von Rautenkranz Hary
Published: August 2019

Precipitation as a key parameter in hydrometeorology and other water-related applications always needs precise methods for assessing and predicting precipitation data. In this study, an effort has been conducted to downscale and evaluate a satellite precipitation estimation (SPE) product using artificial neural networks (ANN), and to impose a residual correction method for five separate daily heavy precipitation events localized over northeast Austria. For the ANN model, a precipitation variable was the chosen output and the inputs were temperature, MODIS cloud optical, and microphysical variables. The particle swarm optimization (PSO), imperialist competitive algorithm,(ICA), and genetic algorithm (GA) were utilized to improve the performance of ANN. Moreover, to examine the efficiency of the networks, the downscaled product was evaluated using 54 rain gauges at a daily timescale. In addition, sensitivity analysis was conducted to obtain the most and least influential input parameters. Among the optimized algorithms for network training used in this study, the performance of the ICA slightly outperformed other algorithms. The best-recorded performance for ICA was on 17 April 2015 with root mean square error (RMSE) = 5.26 mm, mean absolute error (MAE) = 6.06 mm, R2 = 0.67, bias = 0.07 mm. The results showed that the prediction of precipitation was more sensitive to cloud optical thickness (COT). Moreover, the accuracy of the final downscaled satellite precipitation was improved significantly through residual correction algorithms.
Assessment of the Physically-Based Hydrus-1D Model for Simulating the Water Fluxes of a Mediterranean Cropping System
Authors: Ventrella Domenico , Castellini Mirko , Di Prima Simone , Garofalo Pasquale , Lassabatère Laurent
Published: August 2019

In a context characterized by a scarcity of water resources and a need for agriculture to cope the increase of food demand, it is of fundamental importance to increase the water use efficiency of cropping systems. This objective can be meet using several currently available software packages simulating water movements in the “soil–plant–atmosphere” continuum (SPAC). The goal of the paper is to discuss and optimize the strategy for implementing an effective simulation framework in order to describe the main soil water fluxes of a typical horticultural cropping system in Southern Italy based on drip-irrigated watermelon cultivation. The Hydrus-1D model was calibrated by optimizing the hydraulic parameters based on the comparison between simulated and measured soil water content values. Next, a sensitivity analysis of the hydraulic parameters of the Mualem–van Genuchten model was carried out. Hydryus-1D determined simulated soil water contents fairly well, with an average root mean square error below 9%. The main fluxes of the SPAC were confined in a restricted soil volume and were therefore well described by the one-dimensional model Hydrus-1D. Water content at saturation and the fitting parameters α and n were the parameters with the highest impact for describing the soil/plant water balance.
Hydraulic Capacity and Efficiency of a Low-Speed Nonpressurized Coil Pump
Authors: Matz Radosław , Błażejewski Ryszard , Nawrot Tadeusz , Pawlak Maciej
Published: August 2019

The paper presents the results of an investigation on hydraulics of a low-speed coil pump for transport of liquids. One of the pump’s advantages is its wide range of potential inclination angles for its rotating shaft, from the horizontal to an almost vertical position. A simplified hydraulic model was developed based on kinematic and geometrical considerations to determine the pump capacity. The model was verified under laboratory conditions using a low-speed coil pump composed of transparent PVC tube (15 mm outer diameter) wound around a cylindrical drum (104 mm external diameter; 550 mm long). Laboratory tests were performed for three angles of inclination of the axis of rotation (20°, 40°, and 60°) and four rotational speeds (10, 20, 30, and 40 rpm). The results of the tests showed satisfactory agreement with the hydraulic model predictions. Energetic efficiency was estimated on the base of electric power measurements and difference of water levels in the two arms of rotating transparent torus, partly filled with water. The hydraulic efficiency of the coil pump is increasing with decreasing rotational speed.
Bayesian Simultaneous Estimation of Unsaturated Flow and Solute Transport Parameters from a Laboratory Infiltration Experiment
Authors: Younes Anis , Zaouali Jabran , Kanzari Sabri , Lehmann Francois , Fahs Marwan
Published: August 2019

Numerical modeling has become an irreplaceable tool for the investigation of water flow and solute transport in the unsaturated zone. The use of this tool for real situations is often faced with lack of knowledge of hydraulic and soil transport parameters. In this study, advanced experimental and numerical techniques are developed for an accurate estimation of the soil parameters. A laboratory unsaturated flow and solute transport experiment is conducted on a large undisturbed soil column of around 40 cm length. Bromide, used as a nonreactive contaminant, is injected at the surface of the undisturbed soil, followed by a leaching phase. The pressure measurements at different locations along the soil column as well as the outflow bromide concentration are collected during the experiment and used for the statistical calibration of flow and solute transport. The Richards equation, combined with constitutive relations for water content and permeability, is used to describe unsaturated flow. Both linear and non-equilibrium mobile–immobile transport models are investigated for the solute transport. All hydraulic and mass transport parameters are inferred using a one-step Bayesian estimation with the Markov chain Monte Carlo sampler. The results prove that the pressure and concentration measurements are able to identify almost all hydraulic and mass transport parameters. The mobile–immobile transport model better reproduces the infiltration experiment. It produces narrower uncertainty intervals for soil parameters and predictive output concentrations.
Wavelet Coherency Structure in Open Channel Flow
Authors: Chen Kebing , Zhang Yifan , Zhong Qiang
Published: August 2019

Many studies based on single-point measurement data have demonstrated the impressive ability of wavelet coherency analysis to catch the coherent structures in the wall-bounded flows; however, the question of how the events found by the wavelet coherency analysis relate to the features of the coherent structures remains open. Time series of velocity fields in x–y plane of the steady open channel flow was obtained from a time-resolved particle imaging velocimetry system. The local wavelet spectrum found shows that one of the main energetic scales in open channel flows is 3h motions. The wavelet coherent coefficients of u and v series from the same measurement points successfully detected the occurrence and the scale of these 3h motions, and the phase angle indicates their inside velocity structure is organized by the Q2 and Q4 events. The wavelet coherency analysis between different measurement points further reveals the incline feature of the 3h scale motions. All the features of this 3h motion found by the wavelet coherency analysis coincide well with the flow field that is created by the passing of hairpin packets.
Metodologías de detección de outliers en datos espaciales, temporales y espacio-temporales
Authors: Blasco Fernández Isabel
Published: August 2019

En la obtención de conjuntos de datos se pueden detectar registros con valores mucho mayores o menores a los usuales. Dichos registros, denominados outliers, pueden ser correctos, o ser el resultado de errores de captura o del procesado de los datos. El estudio y la detección de outliers ayuda a revelar información valiosa de los conjuntos de datos, así como a depurar las bases de datos de información que pueda ser errónea. En este trabajo se describen distintos métodos de detección de outliers propuestos recientemente y aplicados al marco espacial y espacio-temporal, junto con los resultados de su aplicación. Entre las propuestas se abordan métodos puramente espaciales, puramente temporales y otros mixtos que han demostrado su valía en ensayos controlados. Entre otros se considerarán: 1) emplear un algoritmo que tiene en cuenta los datos temporales y combina las ventajas del clustering y la aproximación basada en la densidad; 2) comparar el valor obtenido por un sensor con el valor esperado calculado de forma incremental, al tener en cuenta la correlación temporal de los datos que muestran una correlación espacial en el pasado reciente; 3) plantear un algoritmo que detecta outliers en grandes bases de datos espacio-temporales a partir del uso conjunto de la información espacial, no espacial y valores temporales; 4) detectar outliers en bases de datos temporales a partir de reglas de asociación extraídas del comportamiento normal de los objetos de un conjunto de datos, de forma que se definen relaciones entre los atributos y el tiempo; 5) detectar los outliers en las propiedades globales del conjunto de datos, en contraste con la mayoría de métodos existentes que lo aplican de forma local y 6) asignar, para el caso específico de los outliers espaciales, diferentes pesos para diferentes vecinos a la hora de calcular el objeto central, determinando
Geografía del carbono en alta resolución en bosque tropical amazónico del Ecuador utilizando tecnología LiDAR aerotransportada
Authors: Molina S. Xavier , Farjas A. Mercedes , Ojeda M. Juan Carlos
Published: August 2019

La estimación de la biomasa de la vegetación terrestre en bosque tropical es un tema de gran interés para reducir las emisiones de carbono asociadas a la deforestación y la degradación forestal (REDD+). Las estimaciones de densidad de carbono sobre el suelo (ACD) en base a inventarios de campo y datos provenientes de sensores aerotransportados, en especial con sensores LiDAR, han conducido a un progreso sustancial en el cartografiado a gran escala de las reservas de carbono forestal. Sin embargo, estos mapas de carbono tienen incertidumbres considerables, asociadas generalmente al proceso de calibración del modelo de regresión utilizado para producir los mapas. En este estudio se establece una metodología para la calibración y validación de un modelo general de estimación de ACD usando LiDAR en el Parque Nacional Yasuní en Ecuador. En el proceso de calibración del modelo se considera el tamaño y la ubicación de las parcelas, la influencia de la topografía y la distribución espacial de la biomasa. Para el ajuste y validación del modelo se propone un esquema de muestreo estratificado por posiciones topográficas (valle, ladera y cima). La validación del modelo general para toda la zona de estudio presentó valores de RMSE= 5.81 Mg C ha-1, R2 = 0.94 y sesgo= 0.59, mientras que, al considerar las posiciones topográficas, el modelo presentó valores de RMSE= 1.67 Mg C ha-1, R2= 0.98 y sesgo= 0.23 para el valle; RMSE= 3.13 Mg C ha-1, R2= 0.98 y sesgo= - 0.34 para la ladera; y RMSE= 2.33 Mg C ha-1, R2= 0.97 y sesgo= 0.74 para la cima. Los resultados muestran el potencial de los datos LiDAR para caracterizar la estructura vertical de la vegetación en un bosque altamente diverso, permitiendo realizar estimaciones precisas de ACD, y conocer patrones espaciales continuos de la distribución de la biomasa aérea
ENSURING EPIDEMIOLOGICAL SAFETY OF THE POPULATION DURING THE HOSTING THE XXI FIFA WORLD CUP IN SAINT-PETERSBURG IN 2018
Authors: Bashketova N.S. , Chkhindzheriya I.G. , Tel’nova N.V. , Gaevaya E.A.
Published: August 2019

We presented the results of ensuring epidemiological safety during the hosting international sport mass events in Saint-Petersburg in 2018. An integrated approach to preventive measures and interdepartmental cooperation allows us to predict possible epidemiological risks, prevent the development of emergency situations of sanitary and epidemiological nature, including those of international importance and ensure a stable epidemiological situation on infectious diseases.
ON THE ACTIVITY OF ROSPOTREBNADZOR OFFICE
IN THE ROSTOV REGION TO ENSURE SANITARY AND EPIDEMIOLOGICAL
WELLBEING DURING THE PREPARATION AND HOSTING THE 2018 FIFA WORLD
CUP IN ROSTOV-ON-DON
Authors: Kovalev E.V. , Konchenko A.V. , Korzhov S.A. , Rodionova M.M. , Akinina S.K. , Kalinina M.V. , Ponomareva E.A. , Buzakin D.I.
Published: August 2019

Activities, including organizational ones, within monitoring and control and surveillance activities
aimed at ensuring sanitary and epidemiological wellbeing of guests and games participants on the territory
of the host city, sports facilities, accommodation places and catering conducted by Rospotrebnadzor
office in the Rostov region during the preparation and hosting the 2018 FIFA World Cup Games in Rostov-
on-Don are presented.
ON THE ENSURING
OF SURVEILLANCE ON ACCOMMODATION FACILITIES, SPORTS FACILITIES
AND LIVING ENVIRONMENTAL FACTORS DURING THE PREPARATION AND
HOSTING THE 2018 FIFA WORLD CUP IN MOSCOW
Authors: Andreeva E.E. , Khudoborodov A.I. , Kosycheva T.V. , Latypov A.R. , Zabolotneva K.M.
Published: August 2019

The paper shows the work experience of the surveillance on accommodation facilities, sports facilities and living
environmental factors in Moscow: the state of water and sewage supply city, level of air pollution, water
quality of surface water bodies, including water bodies allowed for swimming, soil on the epidemiological important
territories and areas of sports facilities. We presented the results of activity to control the sanitary and
hygienic condition of sports facilities, temporary accommodation of guests and participants of the World Cup,
food quality and environmental facilities.
JUSTIFICATION FOR HYGIENIC OPTIMIZATION OF PRIMARY
SCHOOL STUDENTS' PHYSICAL EDUCATION ORGANIZATION BASED ON THE
DIFFERENTIATED ASSESSMENT OF THEIR PHYSICAL FITNESS
Authors: Morgachev O.V.
Published: August 2019

We evaluated the physical fitness of 146 primary school students (68 boys and 78 girls) in the dynamics of the
school year in order to substantiate the hygienic optimization of physical education organization based on a
differentiated approach taking into account the sex of students. Results' analysis revealed that the age period of
8–9 years is a sensitive period for the development in children of speed, power, speed-strength and
coordination body capabilities. It is shown that in order to increase the efficiency of physical education, it is
advisable to conduct physical education classes differentially depending on the gender of the students.
TO THE ORGANIZATION AND CARRYING
OUT ACTIVITIES ON CONTROL WITHOUT INTERACTION WITH LEGAL
ENTITIES AND INDIVIDUAL ENTREPRENEURS IN THE IMPLEMENTATION OF
SOCIO-HYGIENIC MONITORING
Authors: Perezhogin A.N. , Zhdanova-Zaplesvichko I.G.
Published: August 2019

We proposed an algorithm for organizing and carrying out activities on control without interacting
with legal entities and individual entrepreneurs in the course of state social and hygienic monitoring
(SHM). Methodological approaches to the development of the Order of tasks' drawing up for carrying
out these activities, the requirements for their content, as well as the drawing up the activities’ results
on control without interaction with legal entities and individual entrepreneurs in the course of SHM by
specialists of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing
were suggested.
Наука к 80-летнему юбилею АО «МосводоканалНИИпроект»
Authors: Primin O.
Published: August 2019

Приводятся сведения о деятельности научной части института МосводоканалНИИпроект в канун его 80летнего юбилея. Основное направление работы в области повышения надежности и экологической безопасности городских систем инженерного жизнеобеспечения города. В последние годы разработаны крупномасштабные научнотехнические программы и проекты генеральных схем развития водного хозяйства федерального, регионального и городского уровней. Создана методология выбора технологических схем очистки природных вод для питьевых целей на основании принципа наилучших доступных технологий. Осуществляется научное сопровождение эксплуатации и проектирования инженерных систем жизнеобеспечения г. Москвы. Институт обладает инновационными решениями в следующих областях: технологии очистки природных и сточных вод автоматизация технологических процессов при очистке воды и переработке отходов планирование модернизации и развития водопроводной и канализационной сетей города с целью снижения всех видов потерь воды выбор технологий и методов бестраншейного ремонта и прокладки труб без проведения земляных работ разработка систем мусороудаления, переработки и утилизации отходов производства и потребления разработка электронных моделей систем водоснабжения и водоотведения городов и поселений России информационные технологии для контроля эксплуатации систем водоснабжения и водоотведения

The information on the activities of the research division of MosvodokanalNIIproject Institute on the eve of its 80th anniversary is presented. The main direction is research in the field of improving the reliability and environmental safety of urban life support engineering systems. In recent years largescale scientific and technical programs and draft master plans of the development of water management at the federal, regional and urban levels have been compiled. A methodology has been developed to select process flow schemes of natural water treatment for drinking purposes based on the principle of the best available technologies. Scientific support is provided for the operation and design of life support engineering systems for the city of Moscow. The Institute is applying innovative solutions in the following areas: natural and wastewater treatment technologies automation of water treatment and waste processing planning the upgrade and development of the water distribution and sewer networks of the city in order to reduce all types of water losses selection of technologies and methods of trenchless pipe repair and laying without excavation development of systems of solid waste disposal, processing and utilization of industrial and consumer waste development of electronic models of water supply and wastewater disposal systems in cities and settlements of Russia information technologies for monitoring the operation of water supply and wastewater disposal systems.
Изменение качества природной воды источника централизованного водоснабжения при ее транспортировке
Authors: Govorov O. , Govorova Z. , Rudich U.
Published: August 2019

Рассмотрены вопросы трансформации качества воды природного источника водоснабжения при ее транспортировке по водоводам большой протяженности от водозабора до площадки водопроводных очистных сооружений и причины, влияющие на изменение качественного состава воды. Приведены результаты исследований изменения качества воды природного водоисточника, характеризующегося малой мутностью, средней цветностью, сезонным развитием фитопланктона и содержанием органических соединений. Установлено, что в отдельные периоды года происходит как улучшение, так и ухудшение качества транспортируемой по водоводам воды по показателям: перманганатная окисляемость, общее микробное число, численность и биомасса фитопланктона в несколько раз, вследствие чего возрастает в несколько раз нагрузка на сооружения по загрязняющим веществам и снижается эффективность процесса водоочистки. Постоянный мониторинг и систематизация данных по изменению качества воды позволят своевременно корректировать режимы и параметры работы водоочистных сооружений, тем самым обеспечивая стабильную эффективность очистки воды до нормативных требований.

The issues of the water quality transformation from a natural water supply source during transportation by longdistance water mains from the water intake to the water treatment facilities site and the reasons affecting the changes in the qualitative composition of water are considered. The results of the studies on the changes in the water quality of a natural water source characterized by low turbidity, medium color, seasonal growth of phytoplankton and the concentration of organic compounds are presented. It has been established that in certain periods of the year both the improvement and deterioration of the quality of water transported by water mains by several times occur in terms of the following indicators: permanganate value, total microbial count, phytoplankton count and biomass, resulting in several times increase in the pollution load on the treatment facilities and decrease in the efficiency of the water treatment process. Continuous monitoring and systematization of data on the changes in water quality will make it possible to timely adjust the modes and parameters of water treatment plants, thereby ensuring sustainable water treatment efficiency according to the regulatory requirements.
Методика гидравлического расчета инновационных конструкций системы отвода поверхностных сточных вод
Authors: Vereshchagina L. , Ten A. , Gromov G. , Khudiakova D.
Published: August 2019

Представлена методика гидравлического расчета открытых каналов (лотков) системы водоотвода АСО Qmax. Каналы предназначены для сбора и отведения поверхностных (дождевых, талых и поливомоечных) сточных вод с городских территорий различного функционального назначения: паркингов, складских комплексов, торговых центров, транспортных терминалов, автомагистралей, объектов дорожного сервиса, промышленных зон с интенсивным движением грузового автотранспорта, морских и речных причалов, аэродромов, спортивных объектов, внутриквартальных, парковых и других территорий, где допускается использование открытых систем водостока. Методика разработана специалистами АО МосводоканалНИИпроект с учетом законодательства и нормативнометодических документов Российской Федерации, регламентирующих проектирование систем отведения и очистки поверхностных сточных вод с территории поселений. В основе методики результаты экспериментальных исследований по определению гидравлических характеристик каналов системы водоотвода АСО Qmax, которые являются разновидностью открытых лотковых систем и широко используются в странах ЕС для благоустройства территорий.

The method of hydraulic calculation of open canals of the surface runoff drainage system ACO Qmax is presented. The canals are designed to collect and drain surface (rain, snowmelt and street flush water) runoff from urban areas of various functional purposes: parking lots, warehouse complexes, shopping centers, transport terminals, highways, service area facilities, industrial areas with heavy traffic, marine and river terminals, airfields, sports facilities, local park and other areas where the use of open drainage systems is allowed. The method was developed by the experts of MosvodokanalNIIproject JSC taking into account the legislative, regulatory and procedural documents of the Russian Federation governing the design of systems for the removal and treatment of surface runoff from the territory of settlements. The method is based on the results of experimental studies on determining the hydraulic characteristics of canals of the ACO Qmax drainage system that are a sort of open systems and are widely used in the EU countries for land improvements.
Нормативно-правовое поле в сфере водоснабжения и водоотведения
Authors: Pavlinova I.
Published: August 2019

В настоящее время в России принципиально изменился подход к процессу создания новой нормативной базы и контролю качества продукции. АО МосводоканалНИИпроект уже 80 лет занимается проектированием систем водоснабжения и водоотведения с использованием нормативноправовой базы РФ. Институт не только проектирует, но и имеет большой опыт по созданию нормативных документов (санитарных норм и правил, сводов правил и др.). Проведенный анализ нормативноправовой базы в сфере проектирования, строительства и эксплуатации систем водоснабжения и водоотведения показал, что на федеральном уровне этот вопрос решен, однако на региональном уровне требуется его дальнейшая глубокая проработка. Нередко требуется доработка, а в некоторых случаях и переработка утвержденных ключевых документов. Избежать недоработок в нормативной базе возможно лишь при тщательном анализе технических и технологических решений с привлечением широкого круга специалистов и при корректном внесении изменений в действующие нормативноправовые акты.

At present the approach to the process of developing a new regulatory framework and product quality control has been essentially changed. MosvodokanalNIIproject JSC already 80 years has been designing water supply and sanitation systems with the use of the RF regulatory and legal framework. Aside from designing the Institute has been well experienced in developing regulatory documents (sanitary norms and rules, codes of practice etc.). The analysis of the regulatory and legal framework conducted in the field of designing, constructing and operating water supply and sanitation systems shows that this matter has been settled at the federal level however, at the regional level its indepth analysis is needed. Every so often improvement and, in some cases, revision of the approved key documents is required. Avoiding shortfalls in the regulatory framework is possible only with the careful analysis of the technical and technological solutions involving a wide range of experts and with the correct amendments to the effective regulatory and legal acts. Key words: regulatory and legal framework, water supply and sanitation systems, design, construction, operation.
Investigation of the influence of the amount of ethylsilicate, sol based on it and phenol-formaldehyde resin on the strength properties of non-pergarnic magnesia carbon refractories
Authors: Borisenko О. N. , Logvinkov S. M.
Published: August 2019

Using the full factorial experiment, the influence of the number of modifiers: ethylsilicate (Z1 = 0.5 − 1.5 %), sol based on it (Z2 = 0.25 − 0.75 %) and liquid phenol formaldehyde resin (Z3 = 3.0 − 4.0 %) on the strength of periclase-carbonaceous materials. It has been established that in order to obtain strong non-perliquid periclase-carbon refractories, the maximum amount of phenol-formaldehyde resin (4 %), ethylsilicate (1.5 %) and the minimum amount of sol based on ethylsilicate (0.25 %) should be included in the charge composition.
Structure of the system SrO—SiO2—TiO2 and its importance in the technology of technical ceramics
Authors: Pitak Ya. N. , Lisachuk G. V. , Krivobok R. V. , Pitak O. Ya. , Chirkina М. А. , Grebenyuk A. P. , Karputin B. A.
Published: August 2019

Coexisting phases in the system SrO—SiO2—TiO2 are established. The elementary triangles, their relative area and asymmetry degree of the system SrO—SiO2—TiO2 are given. Geometrical-topological characteristics of the phases of the system are given. The areas of composition of the system, the most promising in technology of technical ceramics, are determined.
Technical ceramics with predetermined electrophysical properties based on system ZnO—SrO—Al2O3—SiO2
Authors: Fedorenko O. Yu. , Lisachuk G. V. , Prytkina M. S. , Krivobok R. V. , Gusarova I. A.
Published: August 2019

Modern high-temperature materials designed to radio-engineering systems protecting from external influences are considered. The obtaining possibility of radio-transparent ceramic, consists of Willemite and Slavsonite, at a temperature of 1200 °C has been studied. It is shown that the obtained ceramic materials satisfy the radio-transparent materials requirements by dielectric characteristics (ε < 10, tgδ = 10–2 ÷ 10–4). It was established that to preserve the concomitant phases of Hannite and Zincite, which impair the dielectric characteristics of the material, it is necessary to maintain the ratio of Willemite to Slavsonite as 1 : 1, taking into account the stoichiometry of these phases. This makes it possible to obtain the radio-transparent ceramic materials of the Willemite-Slavsonite composition with a low dielectric permittivity (ε = 5.9) and insignificant dielectric losses (tgδ = 0.004).
Tialit- and mullite-tialite containing ceramic in the MgO—SiO2—Al2O3—TiO2 system based on domestic raw materials
Authors: Lisyutkina M. Yu. , Ryschenko M. I. , Fedorenko E. Yu. , Daineko K. B. , Shevtsov A. V.
Published: August 2019

The aim of the paper is to justify the choice of the region of the system MgO—Al2O3—TiO2—SiO2, which is promising for the production of functional ceramics under conditions of low temperature synthesis. The structure of the A3S2—M2A2S5—AT—S tetrahedron in detail is considered (Тe = 1400 °C), it found that the minimum eutectic of this region is four-component. Compositions based on the above-mentioned tetrahedron are promising for the synthesis of chemically and thermally stable ceramics. Optimization of tialite and mullite-tialite ceramics at a synthesis temperature of 1250 °C has been carried out while maintaining the ratio MgO : TiO2 = 0.18 in the raw mixtures. The dependencies of the properties of materials on the compositions of the ceramic masses were received by mathematical modeling. Mass compositions of functional ceramics in conditions of low-temperature synthesis with high performance indicators have been developing.
External quality control of chemical-analytical units of refractory enterprises in 2016
Authors: Bondarenko E. A. , Varganov V. V. , Konchinko N. N.
Published: August 2019

External quality control of the chemical-analytical departments of the central factory laboratories was carried out: PJSC Krasnoarmeysky Dinas Factory, PJSC Chasovoyarsk Refractory Plant, PJSC Velikoanadol Refinery Plant. During the chemical analysis of samples of refractories of the listed enterprises, the analysis methods, equipment and materials described in DSTU 3305(3, 4, 5)—96 (GOST 2642.(3, 4, 5)—97) — gravimetric (SiO2), complexometric (Al2O3), photometric (Fe2O3). As a result of the work carried out, conclusions were drawn up in which the quality of the work of the chemical analytical units of the central factory laboratories of the PJSC “Krasnoarmeysky Dinas Factory”, PJSC “Chasovoyarsk Refractory Plant”, and PJSC “VELIKOANADOL REFRACTORY PLANT” was considered satisfactory.
Evaluating Critical Success Factors of ERP Implementation in SMEs
Authors:   Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Guntur, A P, India., Kiran Talluri Sai , Reddy A Vasu Deva ,   Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Guntur, A P, India.
Published: August 2019

This paper is aimed at reviewing present state of the art (1998-March 2019) on the impact of Enterprise Resource Planning (ERP) implementation in Small and Medium Enterprises (SMEs). It includes critical success factors and critical failure factors.The technique depends on writing survey for optional information gathering. It characterizes the expressions that are utilized to get explore papers from databases and advanced studies on the ERP implementation in SMEs. It additionally incorporates the consideration and prohibition criteria to improve nature of papers. At that point methodical audit is made on the accessible papers to research the effect of ERP usage in SMEs.Critical factors are identified for success and failure of ERP implementations and actual impact of the same on SMEs (add actual success and failure factors here besides impact). The research found in this paper has limitations in terms of the period of which research papers have been reviewed. An implicit limitation is that it does not consider an empirical study except focusing on the state of the art found in the research area. However, its insights will have potential benefits and the directions for future work helps in further scope of the research. This paper contributes to the research on the impact of ERP implementation on SMEs either positively or negatively. It discovers critical success factors, critical failure factors and impact through secondary data collection method. The insights will help SMEs and stakeholders of SMEs and ERP service providers to know the reasons for failure or success and take necessary course of action.
Internal Curing Efficiency of Pre-Wetted Lightweight Fine Aggregates on Strength Parameters of Concrete
Authors:   Post graduate student, Gudlavalleru Engineering College, Gudlavalleru, India., Krishna T. Mohan , Devi K. Prafulla ,   Asst. Professor, Department of Civil Engineering College, Gudlavalleru Engineering College, India
Published: August 2019

Internal cured concrete (ICC) using pre-wetted lightweight aggregates is to replace conventional type of curing. Normally curing for conventional type is done by external to internal, which requires a large membrane and a large amount of water is required to do this type of procedure and the water which we use for curing may get runoff or get evaporated. But in ICC type of curing it cure inside to outside, the pre-wetted lightweight aggregates provides sufficient moisture to hydrate cement inside the concrete. The pre-wetted light weight aggregates, which stores water inside and acts as a reservoir. It release water when hydration process is done. Lightweight aggregates such as expanded clay or shale, vermiculite, pumice, slate, perlite having high water absorbing capacity are generally used for internal cured concrete. In this study, vermiculite and expanded clay had been used as replacements of fine aggregate, 2.5%, 5%, 7.5%, 10% and 12.5% are replaced for vermiculite and 5%, 10%, 15%, 20% and 25% for expanded clay.
Del Año del Libertador a la Campaña Echeverría: las figuras de Carlos Astrada y Héctor P. Agosti en la disputa por la historia nacional
Authors: Prestía Martín
Published: August 2019

La primera parte del presente trabajo busca brindar una visión panorámica de algunos tópicos que el peronismo puso en juego a la hora de forjar su tradición. Correlativamente, se ofrecerá también una somera presentación del modo en que ese fenómeno político fue representado desde la oposición. Se pondrá especial énfasis en las campañas que se llevaron a cabo teniendo como punto nodal las figuras del libertador San Martín (1950) y Esteban Echeverría (1951), oficialista y opositora respectivamente, que proporcionaron temas y tópicos que permitían re-situar el presente en una línea histórica que conectaba con el pasado nacional. En la segunda parte, la apropiación de la figura de Esteban Echeverría permitirá introducir a dos autores, Carlos Astrada (1894-1970) y Héctor Agosti (1911-1984), para quienes tematizar
al pensador y poeta romántico respondía a trayectorias personales, a un tiempo que pueden leerse como una contribución a las opciones políticas en que ambos se encolumnaban: peronismo y comunismo. Así, mientras la voz astradiana será una de las pocas que desde el oficialismo se había alzado para intentar recuperar la figura de Echeverría, Agosti la utilizará para intentar renovar la tradición política comunista local, demasiado deudora de los dictámenes de la URSS. El trabajo cierra con una serie de consideraciones en torno al derrotero intelectual de ambos pensadores tras el golpe de estado que destituyó a Perón en 1955.
El III Congreso Nacional de Filosofía. Un espacio académico desmembrado bajo la última dictadura en Argentina
Authors: Belloroso Lucía A.
Published: August 2019

Este trabajo se inscribe en el estudio de las implicaciones de la política en la producción filosófica y en los mecanismos de consolidación del espacio académico-filosófico en Argentina. En primer lugar, nos detendremos a estudiar la situación universitaria durante el
periodo de la última dictadura militar en Argentina (1976-1983), para luego poner el foco en el III Congreso Nacional de Filosofía, considerado como uno de los observatorios
privilegiado para analizar las prácticas disciplinares y su entrecruzamiento con el ámbito político. En el trabajo intentaremos dar cuenta de este evento, que, entre cooptación y resistencia, resulta una tentativa particular por articular y consolidar un campo filosófico desmembrado durante la dictadura.
Solidaridad desde México. Dos cartas entre Eduardo Nicol y Francisco Romero en torno a las políticas universitarias
Authors: Schmich Niklas , López Forjas Manuel
Published: August 2019

El texto contextualiza brevemente el intercambio epistolar entre Eduardo Nicol y Francisco Romero en el marco de la renuncia de Romero a sus cátedras universitarias durante el primer peronismo y el rechazo de Nicol a la invitación al Primer Congreso Nacional de Filosofía de 1949. Después de reconstruir cómo se fraguó la relación intelectual entre ambos, se ofrece al lector la transcripción íntegra de dos cartas que sintetizan precisamente la empatía que Nicol mostró por Romero y sus descripciones sobre la crisis universitaria.
Sarcoma de Kaposi y enfermedad de Castleman multicéntrica VHH-8 positivo - VIH Negativo
Authors: Rodríguez Arrieta Luis Antonio , Rada Gener Mahaht , Salazar Luis Antonio , Sierra Rita Magola
Published: August 2019

El sarcoma de Kaposi y la enfermedad de Castleman multicéntrica/virus herpes humano-8 positivo/virus de la inmunodeficiencia humana negativo representan un subgrupo etiológico dentro del espectro clínico de las enfermedades asociadas al virus herpes humano-8 positivo, inicialmente fueron consideradas dos entidades aisladas. El virus tiene un papel protagónico por su tropismo por el tejido linfoide y su potencial oncogénico. La presencia de sarcoma de Kaposi y enfermedad de Castleman multicéntrica/virus herpes humano-8 (VHH-8) positivo/virus de la inmunodeficiencia humana (VIH) negativo sugiere la posibilidad de una deficiencia inmunológica subyacente. Se presenta un caso de una mujer de 67 años de edad con dermatosis en extremidades de curso indolente y aparición posterior de múltiples adenomegalias, esplenomegalia además síntomas sistémicos. Se destaca el abordaje diagnóstico, la coexistencia de dos enfermedades etiológicamente ligadas al virus herpes humano-8, sin asociación de inmunosupresión
Trabajos de investigación residentes
Authors: Residentes Residentes
Published: August 2019

TIR-1. ANEMIA ADQUIRIDA EN EL HOSPITAL Y FACTORES ASOCIADOS: UNA COHORTE RETROSPECTIVA DE PACIENTES MEDICOS HOSPITALIZADOS (MATEUS JUAN, ALZA JHONGERT, CÁRDENAS JORGE, CASTAÑEDA, ANDRÉS, WANCJER BENJAMÍN)

TIR-2. USO DE LA ESCALA DE CHARLSON COMO PREDICTOR INDEPENDIENTE DE ESTANCIA HOSPITALARIA PROLONGADA EN PACIENTES ADULTOS AL MOMENTO DE INGRESO A URGENCIAS (GARCÍA ÁNGEL ALBERTO, RODRÍGUEZ MARÍA ANGÉLICA, SOTELO JORGE ENRIQUE, MAYORGA VIVIANA, SERRANO PAULA, JURADO NATALLIE, PARIS GABRIELA, JIMÉNEZ CAMILO, GARZÓN ANDRÉS, CANO CARLOS ALBERTO, MORENO ATILIO, AGUIAR LEONAR)

TIR-3. EFICACIA DE LA TRIPLE TERAPIA EN PACIENTES DIABÉTICOS TIPO 2 NO CONTROLADOS: ESTUDIO EN VIDA REAL (BEDOYA VANESSA, OSORIO LUIS M., MUÑOZ JENNY, SALGADO CARLOS, CASANOVA MARÍA E., CARVAJAL REYNALDO Y ABREU ALÍN)

TIR-4. FACTORES DE RIESGO ASOCIADOS A ESTANCIA HOSPITALARIA PROLONGADA EN PACIENTES CON FALLA CARDÍACA AGUDA (ARBELAEZ-COLLAZOS LINA, CALVO-BETANCOURT LAUREN, VALENCIA-MEJIA MARGARITA, JUAN MARIETTA, AMAYA NICOLAS, JUAN EMILIO, MARIÑO ALEJANDRO, GARCIA-PEÑA ANGEL. )

TIR-5. ALTERACIONES HEMATOLÓGICAS EN PACIENTES COLOMBIANOS CON LUPUS ERITEMATOSO SISTÉMICO (SANTAMARÍA-ALZA YEISON, COY QUIROGA AMALIA, ALARCÓN GÓMEZ ZULLY MARCELA, SÁNCHEZ-BAUTISTA JULIÁN DAVID, FAJARDORIVERO JAVIER ENRIQUE, FIGUEROA PINEDA)

TIR-6. FACTORES PREDICTORES DE MORTALIDAD EN PACIENTES CON ENFERMEDAD CORONARIA Y COMPROMISO DEL TRONCO PRINCIPAL IZQUIERDO (MIRANDA-ARBOLEDA ANDRÉS F., CARDONA DANIEL, GARCÍA KAREN, URIBE CARLOS E., FERNÁNDEZ-CADAVID ANDRÉS, RODRÍGUEZ ARTURO E., SENIOR JUAN M)

TIR-7. CONCORDANCIA ENTRE ESCALAS FRAMINGHAM ATP III, SCORE Y ACC/AHA 2013, EN UNA COHORTE DE PACIENTES EN UN HOSPITAL DE CUARTO NIVEL EN EL AÑO 2015 (MANCERA RINCÓN PEDRO, GIRAL GIRALDO HELMAN EDUARDO, RIZO TELLO VÍCTOR ZEIN, BARRERA GARAVITO EDGAR CAMILO

TIR-8. RENDIMIENTO DIAGNÓSTICO DE TRES REGLAS DE PREDICCIÓN CLÍNICA PARA EMBOLIA PULMONAR (ORTIZ SANTIAGO, FAIZAL IVETTE, AGUIRRE GUILY, CEPEDA ANDRÉS, MARTINEZ LAURA, RAMÍREZ DAVID)

TIR-9. COMPORTAMIENTO DEL SINDROME DE CUSHING EN UN CENTRO DE SALUD NIVEL IV DE LA CIUDAD DE CALI (SALGADO CIFUENTES CARLOS ALBERTO, MUÑOZ LOMBO JENNY PATRICIA, BEDOYA JOAQUI VANESSA, OSORIO CORREA CINDY VERÓNICA, TABARES BURBANO ADRIÁN ANDRES, ABREU LOMBA ALIN)

TIR-10. ESCALA DE STOP-BANG COMO TAMIZAJE PARA IDENTIFICAR SUJETOS CON RIESGO DE SÍNDROME DE APNEA HIPOPNEA DEL SUEÑO, EN PACIENTES CON CEFALEA PRIMARIA CRÓNICA QUE ASISTEN A LA CONSULTA EXTERNA DE NEUROLOGÍA EN EL HOSPITAL MILITAR CENTRAL (HENRÍQUEZ ORTIZ SAYURIS, HINCAPIÉ DÍAZ GUSTAVO, GUZMÁN MOLANO LUISA, BASTIDAS GOYES ALIRIO, MANTILLA BARBARITA)

TIR-11. IMPACTO DE LOS ANALOGOS DE SOMATOSTATINA EN EL MANEJO DE ACROMEGALIA (OSORIO CORREA CINDY VERÓNICA, SALGADO CARLOS ALBERTO, CARVAJAL REYNALDO, ABREU LOMBA ALIN)

TIR-12. FACTORES ASOCIADOS A INJURIA RENAL AGUDA EN PACIENTES CON TRASPLANTE HEPÁTICO EN UN HOSPITAL DE CUARTO NIVEL (JUAN CASTELLANOS-DE LA HOZ, JULIÁN NARANJO MILLÁN, EDGAR BARRERA GARAVITO)
Geriatría
Authors: Residentes Residentes
Published: August 2019

GE-1 COMPARACION DE TRES FORMULAS PARA CALCULAR LA FUNCION RENAL EN EL ANCIANO (LÓPEZ RAMÍREZ JORGE HERNÁN, SIMANCA CASTRO ELKIN LEONARDO)

GE-2 POLIANGEITIS MICROSCOPICA EN EL ADULTO MAYOR: UNA PRESENTACIÓN TRAICIONERA (TOSCANO ANDRÉS, ZAPATA CARLOS, RAMOS DANIEL, QUINTERO NICOLÁS)
Neurología
Authors: Residente Residente
Published: August 2019

NR-1 SINDROME DE WALLENBERG EN EL CONTEXTO DE UNA EMERGENCIA HIPERTENSIVA (COGOLLO MARYSABEL, USTA EDUARDO)

NR-2 ESCLEROSIS MÚLTIPLE EN UNA PACIENTE CON SECUELAS DE POLIOMIELITIS (COGOLLO MARYSABEL, USTA EDUARDO, BORRÉ DIANA)

NR- 3 SÍNDROME DE VASOCONSTRICCIÓN CEREBRAL REVERSIBLE SECUNDARIO A PARAGANGLIOMA CAROTÍDEO METANEFRINA POSITIVO (ARENAS MAYRA, RICAURTE ANDRÉS, OCAMPO MARIA ISABEL, BARACALDO IVÁN, CORAL JULIANA, JUAN ANDRÉS MEJÍA)

NR-4 SÍNDROME DE CALL-FLEMING Y HEMORRAGIA SUBARACNOIDEA ASOCIADO A INHIBIDOR DE AROMATASA: CLAVES EN SU ABORDAJE DIAGNÓSTICO Y TERAPÉUTICO (CORAL JULIANA, MCCORMICK SILVIA, RICAURTE ANDRÉS, BARRACALDO IVÁN, JIMÉNEZ CAMILO, MEJÍA JUAN)

NR-5 PARÁMETROS DE RESPIRACIÓN MITOCONDRIAL ESTÁN RELACIONADOS CON LA SEVERIDAD DE SÍNTOMAS COGNITIVOS EN PACIENTES CON ENFERMEDAD DE PARKINSON (PAYÁN-GÓMEZ CÉSAR, MOLANO NICOLÁS, MILANESE CHIARA, MASTROBERARDINO PIER GIORGIO)

NR-6 ANGEÍTIS PRIMARIA DEL SISTEMA NERVIOSO CENTRAL EN MUJER CON DEMENCIA RAPIDAMENTE PROGRESIVA: UN REPORTE DE CASO (RIVERA NEIBY, PRIETO JAVIER, BERNAL ADRIANA, MÉNDEZ JUAN, LEGRO GIOVANNI)

NR-7 VASCULITIS DE SISTEMA NERVIOSO CENTRAL EN UNA INSTITUCIÓN DE COLOMBIA DURANTE LOS AÑOS 2014  2018 (PÉREZ MARÍA ALEJANDRA, ZULUAGA JUAN DAVID, ROA LUIS FERNANDO)

NR-8 ENCEFALITIS AUTOINMUNE POR ANTICUERPOS CONTRA EL RECEPTOR DE NMDA (GRANELA KATYA, BUZÓN EVERT, CHÁVEZ SAMUEL, BROCHADO LEONARDO)

NR-9 POLINEUROPATÍA COMO PRESENTACIÓN DE AMILOIDOSIS ASOCIADA A VASCULITIS NECTROTIZANTE (CABRA ANDREA, PRIETO JAVIER, CUERVO MAURICIO)

NR-10 DIPLEJIA FACIAL, VARIANTE ATÍPICA DEL SÍNDROME DE GUILLAIN BARRE (CÁRDENAS JOSÉ M., QUINTERO DIANA C.*, LÓPEZ JUANITA, JARAMILLO WILLIAM, HERNÁNDEZ LINA, KLINGER HELEN, OSORIO JUAN M)

NR-11 SINDROME ENCEFALOPATIA POSTERIOR REVERSIBLE (PRES): DIAGNOSTICO DIFERENCIAL DE CONVULSIONES EN LUPUS ERITEMATOSO SISTEMICO (FUENTES CARLOS, ESPINOSA DAVID, MORA JAVIER, CUERVO JESSICA, OVIEDO PABLO, PRIETO JAVIER)

NR-12 COMPLICACIONES NEUROLOGICAS DEL ALCOHOLISMO (AGUDELO ESTEBAN, ALTMAN DAVID, ÁLVAREZ SEBASTIÁN, ÁNGEL JUAN, ÁNGEL PAOLA, RIOS CESAR AUGUSTO*, BALCAZAR CARLOS MARIO, CARDENAS JOSE MAURICIO)