bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Processing Conditions on the Physical Properties of LLDPE Blown Film
Authors: Shang S. W. , Kamla R. D.
Published: February 2019

The effects of (1) pelletizing extrusion conditions and (2) blowing film extrusion conditions on the physical properties of linear low density polyethylene (LLDPE) films were studied. The results show that better film properties can be obtained when a resin is pelletized at a lower temperature profile and then blown at a higher temperature profile.

As the melt temperature of the blown film extrusion increases, the optical properties of the LLDPE film are improved. The mechanical properties, however, remain essentially the same as those blown at lower temperatures. Extrusion conditions during pelletizing were shown to have a significant effect on the number of "gel" defects in film-with an increase in the melt temperature resulting in more gel.
The diagnosis and management of interstitial ectopic pregnancies: a review
Authors: Brincat Maximilian , Bryant-Smith Alison , Holland T. K.
Published: February 2019

The objective of this article is to review the published literature on the diagnosis and management of interstitial pregnancies (IPs). IPs account for 2–6% of all ectopic pregnancies and have the potential to cause life-threatening haemorrhage resulting in a 2–5% mortality rate. There is little consensus on the best practice for diagnosing and managing interstitial pregnancies. By reviewing the published data, we set out to determine what the best evidence-based practice for the management of interstitial ectopic pregnancies is, what protocols can be used and whether this improves post-operative outcomes and future fertility rates.
An analysis of the foot in turnout using a dance specific 3D multi‐segment foot model
Authors: Carter Sarah L. , Bryant Alan R. , Hopper Luke S.
Published: February 2019

Introduction

Recent three‐dimensional (3D) kinematic research has revealed foot abduction is the strongest predictor of standing functional and forced turnout postures. However, it is still unknown how the internal foot joints enable a large degree of foot abduction in turnout. The primary purpose of this study was to use a dance specific multi‐segment foot model to determine the lower leg and foot contributions to turnout that female university‐level ballets use to accentuate their turnout.

Methods

Eighteen female dance students (mean age, 18.8 ± 1.6 years) volunteered for this study. Retro‐reflective markers were attached to the dancers' dominant foot. Each dancer performed three repetitions of functional turnout, forced turnout and ten consecutive sautés in first position. Repeated measures ANOVA with Bonferroni adjustments for the multiple comparisons were used to determine the kinematic adjustments, hindfoot eversion, midfoot and forefoot abduction, navicular drop (i.e. lowering of the medial longitudinal arch) and first metatarsophalangeal joint abduction between natural double leg up‐right posture and the first position conditions.

Results

Hindfoot eversion (4.6°, p < 0.001) and midfoot abduction (2.8°, p < 0.001) significantly increased in functional turnout compared to the natural double leg up‐right posture. Thirteen dancers demonstrated increased first metatarsophalangeal joint (MTPJ) abduction in forced turnout, however no statistically significant increase was found. Navicular drop during sautés in first position significantly increased by 11 mm (p < 0.001) compared to the natural double leg up‐right posture.

Conclusion

Our findings suggest dancers do pronate, via hindfoot eversion and midfoot abduction in both functional and forced turnout, however, no immediate association was found between forced turnout and first MTPJ abduction. Foot pronation does play a role in achieving turnout. Further prospective research on in situ measures of the lower limb in turnout and injury surveillance is required to improve our understanding of the normal and abnormal dance biomechanics.
Treatment of oral cancers during pregnancy: A case-based discussion
Authors: Sato Kiyoshi , Shimamoto Hiroaki , Mochizuki Yumi , Hirai Hideaki , Tomioka Hirofumi , Shimizu Risa , Marukawa Eriko , Fukayama Haruhisa , Yoshimura Ryoichi , Ishida Hiroo , Harada Hiroyuki
Published: February 2019

Background

Malignancies occur in approximately 1:1000 pregnancies; the most common being breast (46%) and hematological (18%) malignancies. Oral cancers account for only 2% of all cancers in pregnant women, and there are no standard guidelines for the treatment of oral cancer during pregnancy.

Methods

Between 2007 and 2014, our department managed 1109 patients with oral cancers; four (0.4%) had tongue carcinomas during pregnancy. These cases were retrospectively reviewed.

Results

The four women were aged 29–39 (median 32.5) years. Two underwent partial glossectomy at 39 and 40 weeks’ gestation, respectively, one received radiotherapy at 17 weeks’ gestation, and one underwent supraomohyoid neck dissection and hemi-glossectomy with a forearm flap reconstruction.

Conclusion

In addition to tumor factors, the wishes of the patient and her family, gestational age, and fetal and maternal conditions are important factors in deciding on a treatment protocol. Moreover, treatment decisions require multidisciplinary approach.
RETRACTED ARTICLE: Predictability and controlling factors of overpressure in the North Alpine Foreland Basin, SE Germany: an interdisciplinary post-drill analysis of the Geretsried GEN-1 deep geothermal well
Authors: Drews Michael C. , Hofstetter Peter , Zosseder Kai , Straubinger Robert , Gahr Andreas , Stollhofen Harald
Published: February 2019

For the first time, drilling- and velocity-based well analysis and 3D basin modeling were combined to test the predictability and controlling factors of overpressure in the North Alpine Foreland Basin in SE Germany. More specifically, the techniques were tested in the sub-regional context of the deep geothermal well Geretsried GEN-1 (TVD = 4852 m), located in the south of Munich. A 3D basin model based on a total of 20 wells was calibrated to the pressure distribution of four petroleum wells and tested against the Geretsried GEN-1 well. The results demonstrate that overpressure in the North Alpine Foreland Basin SE Germany can be predicted from a simple 3D basin model calibrated to a minimum number of wells. Thereby, disequilibrium compaction likely acts as the main overpressure mechanism in the study area, underpinned by significantly higher sedimentation rates at overpressured locations. 3D basin modeling also confirms the role of Upper Cretaceous shales, which, if present, serve as an important pressure barrier between the under- to normally pressured Jurassic and overpressured Cenozoic basin fill. In addition, overpressure magnitudes of the Chattian might be higher than previously expected. The results of this study have great impact on future drilling campaigns in the North Alpine Foreland Basin in SE Germany. Minimized non-productive time and drilling cost, improved well planning and increased safety are amongst the most important benefits of accurate pore pressure and overpressure prediction. The newly derived insights on the mechanisms of overpressure will greatly influence future geomechanical and tectonic studies, since pore pressure drives rock strength and principle stress magnitudes. Finally, the study is a great example for the importance of an interdisciplinary approach and the incorporation of geological conditions, when investigating drilling-related problems.
Enhanced peer-review for optimising publication of biomedical papers submitted from low- and middle-income countries: feasibility study for a randomised controlled trial
Authors: Pitman Alexandra , Underwood Raphael , Hamilton Adam , Tyrer Peter , Yang Min
Published: February 2019

Background

Biomedical research from low- and middle-income countries (LMICs) is poorly represented in Western European and North American psychiatric journals.

Aims

To test the feasibility of trialling a capacity-building intervention to improve LMIC papers' representation in biomedical journals.

Method

We designed an enhanced peer-review intervention delivered to LMIC corresponding/first authors of papers rejected by the British Journal of Psychiatry. We conducted a feasibility study, inviting consenting authors to be randomised to intervention versus none, measuring recruitment and retention rates, outcome completion and author/reviewer-rated acceptability.

Results

Of the 26/121 consenting to participate, 12 were randomised to the intervention and 14 to the control arms. Outcome completion was 100% but qualitative feedback from authors/reviewers was mixed, with attrition from 5/12 (42%) of intervention reviewers.

Conclusions

Low interest among eligible authors and variable participation of expert reviewers suggested low feasibility of a full trial and a need for intervention redesign.

Declaration of interest

A.P., P.T. and M.Y. are British Journal of Psychiatry editorial board members. During this study P.T. was British Journal of Psychiatry Editor, A.P. was a trainee editor and A.H. was an editorial assistant.
Discrediting experiences: outcomes of eligibility assessments for claimants with psychiatric compared with non-psychiatric conditions transferring to personal independence payments in England
Authors: Pybus Katie , Pickett Kate E. , Prady Stephanie L. , Lloyd Charlie , Wilkinson Richard
Published: February 2019

Background

Recent qualitative research suggests that changes to the way eligibility for welfare payments is determined in the UK may be detrimental to claimants with mental illnesses. No large-scale analysis has been undertaken to date.

Aims

To examine differences between claimants with psychiatric conditions compared with non-psychiatric conditions in the number of claims disallowed following a personal independence payment (PIP) eligibility assessment for existing disability living allowance (DLA) claimants.

Method

Administrative data on DLA claimants with psychiatric conditions transferring to PIP between 2013 and 2016 was compared with claimants with non-psychiatric conditions to explore differences in the number of claims disallowed following an eligibility assessment.

Results

Claimants with a mental illness were 2.40 (95% CI 2.36–2.44) times more likely to have their existing DLA entitlement removed following a PIP eligibility assessment than claimants with musculoskeletal conditions, neurological conditions and diabetes.

Conclusions

PIP eligibility assessment outcomes show marked differences by health condition, raising questions as to whether the process is equitable.

Declaration of interest

None.
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
Authors: Wen Patrick Y. , Touat Mehdi , Alexander Brian M. , Mellinghoff Ingo K. , Ramkissoon Shakti , McCluskey Christine S. , Pelton Kristine , Haidar Sam , Basu Sankha S. , Gaffey Sarah C. , Brown Loreal E. , Martinez-Ledesma Juan Emmanuel , Wu Shaofang , Kim Jungwoo , Wei Wei , Park Mi-Ae , Huse Jason T. , Kuhn John G. , Rinne Mikael L. , Colman Howard , Agar Nathalie Y.R. , Omuro Antonio M. , DeAngelis Lisa M. , Gilbert Mark R. , de Groot John F. , Cloughesy Timothy F. , Chi Andrew S. , Roberts Thomas M. , Zhao Jean J. , Lee Eudocia Q. , Nayak Lakshmi , Heath James R. , Horky Laura L. , Batchelor Tracy T. , Beroukhim Rameen , Chang Susan M. , Ligon Azra H. , Dunn Ian F. , Koul Dimpy , Young Geoffrey S. , Prados Michael D. , Reardon David A. , Yung W.K. Alfred , Ligon Keith L.
Published: February 2019

PURPOSE

Phosphatidylinositol 3-kinase (PI3K) signaling is highly active in glioblastomas. We assessed pharmacokinetics, pharmacodynamics, and efficacy of the pan-PI3K inhibitor buparlisib in patients with recurrent glioblastoma with PI3K pathway activation.

METHODS

This study was a multicenter, open-label, multi-arm, phase II trial in patients with PI3K pathway–activated glioblastoma at first or second recurrence. In cohort 1, patients scheduled for re-operation after progression received buparlisib for 7 to 13 days before surgery to evaluate brain penetration and modulation of the PI3K pathway in resected tumor tissue. In cohort 2, patients not eligible for re-operation received buparlisib until progression or unacceptable toxicity. Once daily oral buparlisib 100 mg was administered on a continuous 28-day schedule. Primary end points were PI3K pathway inhibition in tumor tissue and buparlisib pharmacokinetics in cohort 1 and 6-month progression-free survival (PFS6) in cohort 2.

RESULTS

Sixty-five patients were treated (cohort 1, n = 15; cohort 2, n = 50). In cohort 1, reduction of phosphorylated AKTS473 immunohistochemistry score was achieved in six (42.8%) of 14 patients, but effects on phosphoribosomal protein S6S235/236 and proliferation were not significant. Tumor-to-plasma drug level was 1.0. In cohort 2, four (8%) of 50 patients reached 6-month PFS6, and the median PFS was 1.7 months (95% CI, 1.4 to 1.8 months). The most common grade 3 or greater adverse events related to treatment were lipase elevation (n = 7 [10.8%]), fatigue (n = 4 [6.2%]), hyperglycemia (n = 3 [4.6%]), and elevated ALT (n = 3 [4.6%]).

CONCLUSION

Buparlisib had minimal single-agent efficacy in patients with PI3K-activated recurrent glioblastoma. Although buparlisib achieved significant brain penetration, the lack of clinical efficacy was explained by incomplete blockade of the PI3K pathway in tumor tissue. Integrative results suggest that additional study of PI3K inhibitors that achieve more-complete pathway inhibition may still be warranted.
Sea urchin Paracentrotus lividus immune cells in culture: formulation of the appropriate harvesting and culture media and maintenance conditions
Authors: Pinsino Annalisa , Alijagic Andi
Published: February 2019

The sea urchin is an emergent model system for studying basic and translational immunology. Here we report a new method for the harvesting and maintenance of primary immune cells isolated from adult Paracentrotus lividus, a common Mediterranean sea urchin species. This optimised method uses Coelomocyte Culture Medium, containing a high-affinity Ca2+ chelator, as the ideal harvesting and anti-clotting vehicle and short-term culture medium (≤48 h), and artificial seawater as the master medium that maintains cell survival and in vitro–ex vivo physiological homeostasis over 2 weeks. Gradually reducing the amount of anticoagulant solution in the medium and regularly replacing the medium led to improved culture viability. Access to a robust and straightforward in vitro–ex vivo system will expedite our understanding of deuterostome immunity as well as underscore the potential of sea urchin with respect to biomedicine and regulatory testing.
Leptin induces muscle wasting in kras-driven hepatocellular carcinoma (HCC) model in zebrafish
Authors: Yang Qiqi , Yan Chuan , Wang Xu , Gong Zhiyuan
Published: February 2019

Cancer cachexia affects up to 80% of the patients with advanced solid cancer and leads to excessive muscle wasting. Here, using an inducible zebrafish HCC model driven by oncogenic krasG12V, we observed a progressive muscle wasting phenotype in adult zebrafish, characterized by significant loss of body weight and muscle fibers. By differential feeding, we observed that overfeeding caused fatty liver, accelerated carcinogenesis and muscle wasting. Interestingly, leptin, an obesity hormone, was upregulated in oncogenic hepatocytes and overfeeding groups. We also found a progressively increased leptin expression during human liver disease progression. By using leptin receptor (lepr) knockout fish, we found that tumor fish in the lepr mutant background had a higher survival rate and significantly lower muscle wasting level after tumor induction than the tumor fish in the wildtype background. Chemical inhibitors targeting leptin signaling also alleviated muscle wasting phenotype, indicating that the leptin signaling may be a new therapeutic target for cancer patients with muscle wasting.
The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila
Authors: Bag Indira , Dale Ryan K. , Palmer Cameron , Lei Elissa P.
Published: February 2019

Chromatin insulators are DNA-protein complexes that establish independent higher order DNA domains to influence transcription. Insulators are functionally defined by two different properties: they can block communication between an enhancer and a promoter and also act as a barrier between heterochromatin and euchromatin. In Drosophila, the gypsy insulator complex contains three core components; Su(Hw), CP190 and Mod(mdg4)67.2. Here, we identify a novel role for Chromatin-linked adaptor for MSL proteins (CLAMP) in promoting gypsy chromatin insulator function. When clamp is depleted, gypsy-dependent enhancer blocking and barrier activities are strongly reduced. CLAMP associates physically with the core gypsy insulator complex, and ChIP-seq analysis reveals extensive overlap particularly with promoter-bound CP190 on chromatin. Depletion of CLAMP disrupts CP190 binding at a minority of shared sites, but depletion of CP190 results in extensive loss of CLAMP chromatin association. Finally, reduction of CLAMP disrupts CP190 localization within the nucleus. Our results support a positive functional relationship between CLAMP and CP190 to promote gypsy chromatin insulator activity.
Thermal Lens Microscope and Microchip Chemistry
Authors: Kitamori Takehiko
Published: February 2019

Thermal lens spectrometry was realized under an optical microscope by controlling the chromatic aberration of the objective lens system. This thermal lens microscope (TLM) is ultrasensitive to non-fluorescent molecules and detection at even the yoctomole level in a liquid was confirmed. The TLM is widely applicable, almost the same as spectrophotometry, but its specificity for the analyte species is similarly poor. During development of the TLM equipment, a microchannel fabricated on a glass substrate was used as a sample vessel, which then became a microchemical chip. The generalized microchemical chip design method, micro unit operation (MUO) and continuous flow chemical processing (CFCP) was proposed and a variety of complex chemical processes for analyses, syntheses, and biomedical experiments could be integrated onto the microchemical chip. Therefore, the development of microchemical chips realized significant expansion of the field of microfluidics. Microchemical chips are also suitable devices for separation chemistry, and combination of the TLM and microchemical chips could compensate for the poor selectivity of TLM. These innovative methods will not only impact analytical chemistry but also microfluidics and most certainly other research fields such as biology and medicine. This account of The Chemical Society of Japan Award for Creative Work 2006 introduces these achievements.
Recent advances in understanding RAG deficiencies
Authors: Gennery Andrew
Published: February 2019

Recombination-activating genes (RAG)1 and RAG2 initiate the molecular processes that lead to lymphocyte receptor formation through VDJ recombination. Nonsense mutations in RAG1/RAG2 cause the most profound immunodeficiency syndrome, severe combined immunodeficiency (SCID). Other severe and less-severe clinical phenotypes due to mutations in RAG genes are now recognized. The degree of residual protein function may permit some lymphocyte receptor formation, which confers a less-severe clinical phenotype. Many of the non-SCID phenotypes are associated with autoimmunity. New findings into the effect of mutations in RAG1/2 on the developing T- and B-lymphocyte receptor give insight into the development of autoimmunity. This article summarizes recent findings and places the genetic and molecular findings in a clinical context.
Evaluation of a multi-level intervention to improve postpartum intrauterine device services in Rwanda
Authors: Ingabire Rosine , Nyombayire Julien , Hoagland Alexandra , Da Costa Vanessa , Mazzei Amelia , Haddad Lisa , Parker Rachel , Sinabamenye Robertine , Mukamuyango Jeannine , Smith Julie , Umutoni Victoria , Mork Ellen , Allen Susan , Karita Etienne , Wall Kristin M.
Published: February 2019

Background. The copper intrauterine device is one of the most safe, effective, and cost-effective methods for preventing unintended pregnancy. It can be used postpartum irrespective of breastfeeding to improve birth spacing and reduce unintended pregnancy and maternal-child mortality. However, this method remains highly underutilized.

Methods. We developed a multi-level intervention to increase uptake of the postpartum intrauterine device (PPIUD, defined as insertion up to six weeks post-delivery) in Kigali, Rwanda. High-volume hospitals and health centers were selected for implementation of PPIUD counseling and service delivery. Formative work informed development of a PPIUD counseling flipchart to be delivered during antenatal care, labor and delivery, infant vaccination visits, or in the community. Two-day didactic counseling, insertion/removal, and follow-up trainings were provided to labor and delivery and family planning nurses followed by a mentored practicum certification process. Counseling data were collected in government clinic logbooks. Insertions and follow-up data were collected in logbooks created for the implementation. Data were collected by trained government clinic staff and abstracted/managed by study staff. Stakeholders were involved from intervention development through dissemination of results.

Results. Two hospitals (and their two associated health centers) and two additional health centers were selected. In 6-months prior to our intervention, 7.7 PPIUDs/month were inserted on average at the selected facilities. From August 2017-July 2018, we trained 83 counselors and 39 providers to provide PPIUD services. N=9,020 women received one-on-one PPIUD counseling after expressing interest in family planning who later delivered at a selected health facility. Of those, n=2,575 had PPIUDs inserted (average of 214.6 insertions/month), a 29% uptake. Most PPIUDs (62%) were inserted within 10 minutes of delivery of the placenta.

Conclusions. This successful, comprehensive intervention has the potential to make a significant impact on PPIUD uptake in Rwanda. The intervention is scalable and adaptable to other sub-Saharan African countries.
How to be your practice's leading light
Authors: Memon Shaz
Published: February 2019

Successful online dental marketing depends on great ideas and a big passion for social media. Dental marketing and design expert Shaz Memon forecasts six sensational trends for you and your team
Are you the ace in the pack?
Authors: Anastasi Emma
Published: February 2019

The role of a treatment coordinator adds precious value to a dental nursing career, to a practice and to its patients. Diamond Dental Staff's Emma Anastasi explains why
Isolated submandibular lymph node metastasis in pancreatic adenocarcinoma
Authors: Oyebola Taiwo , Mavilakandy Akash , Conboy Peter , Bhardwaj Neil
Published: February 2019

Pancreatic adenocarcinoma is a highly aggressive malignancy that usually presents at a late stage. Common sites of metastasis include the liver, lung and adjacent lymph nodes. Cervical lymph node involvement has been reported previously but there are no documented cases of submandibular lymph node metastasis in the available literature. We describe a case of pancreatic adenocarcinoma metastasis to the left submandibular lymph node with no confirmed concurrent sites of metastasis.
TÉCNICA E LIBERDADE: MARTIN HEIDEGGER E EUGEN FINK SOBRE O PROBLEMA E A ESSÊNCIA DA TÉCNICA MODERNA
Authors: Giubilato Giovanni Jan
Published: February 2019

A filosofia da técnica representa uma dentre as áreas de estudo mais atuais, além de constituir ainda uma disciplina do pensamento filosófico cuja importância se revela cada vez maior no âmbito acadêmico contemporâneo. O presente trabalho tem a intenção de, num primeiro momento, alcançar uma rigorosa fundamentação conceitual da reflexão filosófica de Heidegger e Fink sobre o fenômeno da técnica e as questões relacionadas à sua essência, que incluem a liberdade e o papel da subjetividade. Essa primeira etapa pretende fornecer os pressupostos teóricos para uma discussão que considera não apenas a reformulação do conceito de “técnica” mas se detém sobre as consequências filosóficas dessa recolocação do problema. No contexto da filosofia finkeana, a questão da técnica adquire importância central não apenas para uma compreensão da filosofia como pedagogia, mas igualmente para uma determinação do filosofar numa perspectiva cosmológica, e como dialética (necessária) entre fenomenologia e ontologia.
FINITUDE E TRANSCENDÊNCIA NA ETAPA DA “METAFÍSICA DO DASEIN” (1927-1930)
Authors: Braga Arnin Rommel Pinheiro , Júnior Nelson José De Souza
Published: February 2019

A problemática da finitude como o horizonte de manifestação do ser é uma das principais temáticas dentro do pensamento de Heidegger. No entanto, ela ganha aspectos novos e evolui a cada etapa do pensamento deste autor, o que dificulta o exercício de tratar este tema desde uma visão totalizante de sua filosofia. Neste sentido, este artigo busca abordar a questão da finitude a partir da etapa do pensamento heideggeriano conhecida como a “Metafísica do Dasein” (1927-1930). Em outras palavras, abordaremos como a questão do desvelamento do ser no horizonte da finitude vai se deslocando do âmbito estrito do Dasein como “cuidado” (Sorge) e “ser-para-a-morte”, para ser abordada de uma maneira mais ampla no conceito de “transcendência”, que garante uma relação de unidade intencional entre Dasein e mundo.
O OUTRO, O SER-COM E A IPSEIDADE NA CONTEMPORANEIDADE
Authors: Falkoski Fernando Matheus
Published: February 2019

A questão da identidade cultural está intrinsecamente ligada à noção de diferença entre o “eu” e o “outro” através da alteridade promovida pela individualidade que cada um carrega em si mesmo como sujeitos singulares. Conquanto, buscaremos explicitar a questão da identidade cultural em Stuart Hall, analisando a obra A identidade cultural na pós-modernidade, a fim de verificar a crise sobre o sujeito que, perguntando pelo quem (?) do outro, se perde em sua própria identidade, não se reconhecendo em si-mesmo e, por vezes, sendo apenas coadjuvante do mundo que o limita e o solicita. Após, pretendemos conectar a questão da identidade cultural de Hall com a questão da ipseidade de Heidegger, propondo que o ser-si-mesmo do Dasein, por estar no horizonte de possibilidades existenciais (ek-sistir), possibilita ele mesmo o sujeito diaspórico se tornar ser-com, na medida em que ele estabelece relações com o outro em suas preocupações e ocupações cotidianas.
La pesada herencia de la dependencia. Competencia capitalista y ganancias extraordinarias en Argentina (2002-2015)
Authors: López Emiliano , Barrera Insua Facundo
Published: February 2019

El presente artículo estudia el patrón de reproducción del capital por medio del análisis de tasas de ganancia sectoriales (1993-2015). Así, se muestra que la ampliación de la disparidad entre tasas puede vincularse con los aportes clásicos de la teoría de la dependencia, siendo resultado de la concentración y extranjerización del capital en la economía desde los años 90 en adelante. Asimismo, como resultado, se evidencia la profundización del perfil primario exportador de la Argentina.
Reformar la seguridad en América Latina. Cartografía de la red transnacional de la seguridad ciudadana
Authors: Lazreg Nordin
Published: February 2019

En este artículo, se evidencia la formación de una red transnacional en torno al concepto de seguridad ciudadana que se ha ido difundiendo en Latinoamérica desde los noventa. Se realiza un análisis sociométrico de red a partir de una base de datos original sobre los foros, considerando que estos permiten la formación de redes sociales y la circulación de las ideas. Con base en este trabajo exploratorio y empírico, se proponen futuras pistas de investigaciones.
Movilización sociolegal transnacional. Extractivismo y Derechos Humanos en América Latina
Authors: Hincapié Sandra
Published: February 2019

En este artículo se argumenta que la movilización sociolegal transnacional en los conflictos socioambientales ligados al extractivismo es una estrategia de acción colectiva en constante crecimiento y expansión en América Latina. Dicha movilización revela la apropiación de los derechos humanos como una herramienta para el activismo por parte de amplios colectivos sociales en defensa del medio ambiente sano. Al analizar empíricamente la tendencia regional de movilización ante el sistema interamericano, se identifican actores, estrategias, diferencias por países y casos paradigmáticos.
APPLICATION OF GEOSTATISTICS IN THE ESTIMATION OF SUJISHAN GRAPHITE DEPOSITS, MONGOLIA
Authors: Song Huang , An Huaming
Published: February 2019

In this paper, the author used mine 3D software to establish the 3D geological model of Sujishan Graphite deposit, and applied geostatistics to estimate the resource, offered references for next exploration and mining. Surpac was used to set up geological database of Sujishan Graphite deposit, topographical DTM, ore body model and grade model, 3D of drilling database, also analysis the spatial grade distribution in reality. Based on geostatistics, drilling samples are composited and statistically analysed and eliminate the impact of outliers. Experimental variograms were constructed for the striking, dipping and vertical directions. Grade and resource are estimated by ordinary kriging. Comparing to the traditional estimation methods, this 3D software gives reliable estimation, which provides references for dynamic management of mine's resource.
EXAMINATION OF THE USABILITY OF BASALT AGGREGATE IN SIFCON
Authors: İpek Metin
Published: February 2019

In this study, the usability of the quartz and basalt rocks as aggregate in Slurry Infiltrated Fiber Concrete (SIFCON) has been examined. In the study, quartz aggregate has been taken as reference and basalt aggregate has been used as a substitute and separately. The aggregates have been ground and classified in the dimensions of 0-0.1 mm (powder) and 0.1-0.6 mm (sand). The physical properties of the aggregates have been determined and SIFCON slurry has been prepared. The samples produced by this slurry have been conducted to Compressive Strength, Flexural Tensile Strength, Fracture Toughness, Ultrasonic Pulse Velocity, Schmidt Hammer tests. Moreover, unit cost has been examined with the different aggregate usages. Consequently; the highest compressive and flexural strength being respectively 99.75 MPa and 32.01 MPa have been reached with the use of quartz aggregate. The compressive strength of the basalt aggregate is 14% lower than that of the quartz aggregate where, its flexural strength almost remained in the same value. It has been observed that basalt aggregate is more economical in terms of unit strength cost. It is suggested that basalt aggregate could also be used in SIFCON as an alternative to the quartz aggregate.
INVESTIGATING OF SEISMIC PARAMETERS OF RC FRAMES REHABILITATED BY ECCENTRICALLY BRACING WITH VERTICAL LINK
Authors: Noruzi Faramarz , Naserabadi Heydar Dashti , Jelodar Hosein Nematian , Dorvar Hosein
Published: February 2019

Most of existing concrete structures do not have suitable seismic performance due to various reasons, therefore they need seismic rehabilitation. One of the seismic rehabilitation method in structural level is using of steel bracing. New investigation of steel bracing can be referred to eccentrically bracing with single vertical link. This method of rehabilitation provides many advantages such as increasing in ductility, stiffness, lateral resistance, architectural compatibility, low weight, and the fewest changes in primary structural system. In this paper, two existing 3- and 9-story RC frames are assessed on the basis of FEMA356. Eccentrically bracing with single vertical link is used for seismic rehabilitation of these frames. The results of nonlinear time history analysis based on the maximum inter-story drift, maximum roof displacement and plastic rotation in critical elements of original and rehabilitated frames for two performance levels of Life safety (LS) and Collapse Prevention (CP) are presented. The results indicate that single vertical link can lead structures to the desired performance level with minimum cost and braced span number.
Currículo sobre la enseñanza del pasado reciente y violencia política en Colombia
Authors: Arias Gómez Diego , Herrera Martha
Published: February 2019

El presente escrito recoge los hallazgos de dos investigaciones centradas en el tratamiento de la violencia política y el conflicto armado en el campo educativo y escolar, específicamente en las particularidades del abordaje de la historia reciente en la escuela colombiana. A partir de la revisión de documentos académicos y la percepción de docentes en ejercicio se pudieron identificar las dificultades y potencialidades que el tema concita, especialmente aquellas relacionadas con los retos de posicionar la categoría historia reciente en el país, la importancia de las apuestas ético-políticas de los docentes para las definiciones curriculares y la ambigüedad de la normativa educativa respecto al tema del conflicto armado interno.
¿Qué saben los estudiantes secundarios de la última dictadura? Fortalezas y debilidades de la formación de ciudadanos en las clases de Historia de escuelas secundarias de la ciudad de La Plata
Authors: De Amézola Gonzalo
Published: February 2019

Este trabajo se ocupa de cómo los alumnos de la escuela secundaria  conocen e interpretan el tema de la última dictadura militar argentina, un contenido considerado central  para su formación como ciudadanos democráticos. Con este propósito se utilizan datos cuantitativos resultantes de una investigación terminada sobre los países del Mercosur y se los contrapone con los obtenidos mediante narrativas de estudiantes de 5º año de un proyecto cualitativo todavía en curso y focalizado en la ciudad de La Plata (capital de la Provincia de Buenos Aires).
Amézola, G. de y Cerri, L. (Coords). (2018). Los jóvenes frente a la Historia: Aprendizaje y enseñanza en escuelas secundarias
Authors: Rocha Milagros
Published: February 2019

.
Elektropolimerisasi Anilin secara Potensiostatik dengan Penambahan Dopan
Authors: Richard Yudhi , Widodo Didik Setiyo
Published: February 2019

Penelitian tentang elektropolimerisasi anilin dengan metode potensiostatik telah dilakukan. Penelitian ini bertujuan untuk memperoleh senyawa polimer polianilin dengan konduktivitas yang tinggi melalui pendekatan elektropolimerisasi. Anilin dielektrolisis menggunakan elektroda besi dan karbon dan ditambahkan H2SO4 hingga terbentuk endapan. Konsentrasi anilin yang digunakan adalah 0,7 M dengan metanol sebagai pelarut. Metode yang digunakan adalah potensiostatik dalam larutan 100 mL pada potensial 5 V selama 20 menit. Karakter produk dari hasil elektropolimerisasi yang terbentuk dianalisis menggunakan spektrofotometer UV-Vis dan FTIR. Hasil yang diperoleh menunjukkan bahwa elektropolimerisasi anilin dengan melibatkan proses doping dengan menggunakan H2SO4 menghasilkan senyawa polianilin yang konduktif.
Identifikasi Senyawa Sitotoksik dalam Ekstrak Kloroform Daun Tempuyung (Sonchus arvensis L.) Menggunakan GC-MS
Authors: Azifa Ayu Ni’mah , Kusrini Dewi , Fachriyah Enny
Published: February 2019

Identifikasi senyawa sitotoksik dari ekstrak kloroform daun tempuyung (Sonchus arvensis L.) menggunakan GC-MS telah dilakukan. Identifikasi ini dilakukan menggunakan metode GC-MS dan uji aktivitas menggunakan metode BSLT (Brine Shrimp Lethality Test). Dari uji aktivitas, diperoleh bahwa fraksi B hasil kolom ekstrak kloroform merupakan fraksi yang sangat sitotoksik dengan harga LC50 = 7,862 ppm. Pada identifikasi fraksi B, diperoleh 29 senyawa dan ada 5 senyawa yang teridentifikasi dengan kelimpahan tertinggi yaitu dibutil ftalat dengan waktu retensi 22,265 menit dan luas area 7,71%, asam palmitat dengan waktu retensi 22,626 menit dan luas area 8,49%, 8,11,14-asam eikosatrieonat dengan waktu retensi 24,4 menit dan luas area 6,95, dioktil adipat dengan waktu retensi 26,517 menit dan luas area 7,90%, serta dioktil ftalat dengan waktu retensi 28,983 menit dan luas area 10,61%.
Synthesis of Alginate-Chitosan Polyelectrolyte Complex (PEC) Membrane and Its Physical-Mechanical Properties
Authors: Hermanto Dhony , Mudasir Mudasir , Siswanta Dwi , Kuswandi Bambang
Published: February 2019

Synthesis of alginate-chitosan polyelectrolyte membrane and the determination of the physical-mechanical properties were carried out. Alginate-chitosan polyelectrolyte complex membrane can be made by mixing hydrosol alginate and chitosan hydrosol with a ratio of 1: 1 at pH 5.28. Membranes of alginate-chitosan polyelectrolyte complexes produced have physical-mechanical properties including load, elongation and elasticity, water absorption and resistance better than the constituent polymers. The results of FTIR spectroscopy analysis showed that there was an electrostatic interaction between alginate and chitosan through protonated amine groups of chitosan and carboxylic groups from alginate. Surface analyses by SEM showed that morphology of alginate-chitosan polyelectrolyte complex membrane was different with single membrane morphology
Effects of Leontice leontopetalum and Bongardia chrysogonum on oxidative stress and neuroprotection in PTZ kindling epilepsy in rats
Authors: Ergul Erkec Ozlem , Arihan Okan , Kara Mehmet , Karatas Ersin , Erten Remzi , Demir Halit , Meral Ismail , Mukemre Muzaffer , Ozgokce Fevzi
Published: February 2019

We investigated the effects of Leontice leontopetalum and Bongardia chrysogonum on apoptosis, gamma-aminobutyric acid (GABAA) receptor positive cell number, cyclin-B1 and bcl-2 levels and oxidative stress in pentylenetetrazol (PTZ) kindling in rats. Kindling was produced by subconvulsant doses of PTZ treatments in rats. Wistar albino rats were divided into 4 groups; Control, PTZ treated (PTZ), PTZ+L. leontopetalum extract treated (PTZ+LLE) and PTZ+B. chrysogonum extract treated (PTZ+BCE) groups. Extracts were given a dose (200 mg/kg) 2h before each PTZ injection. PTZ treatment significantly decreased the glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) activities and bcl-2 levels and increased the total oxidant status (TOS), malondialdehyde (MDA), cyclin B1, oxidative stress index (OSI) and number of neurons that expressed GABAA receptors when compared to the control. LLE and BCE possessed antioxidant activity in the brain and ameliorated PTZ induced oxidative stress, decreased cyclin-B1, increased bcl-2 levels, and kept the GABAA receptor number similar to that of the control despite the PTZ application.
Morphological and molecular characterization of coprinoid fungi newly recorded for the mycobiota of Iran
Authors: Seidmohammadi Elham , Abbasi Saeed , Asef Mohammad Reza
Published: February 2019

Twenty-five specimens of coprinoid fungi were collected during an ongoing survey of agaric fungi in Kermanshah Province, western Iran. The specimens were identified based on morphological characteristics and molecular analysis of internal transcribed spacer sequences. Five species of Coprinellus viz C. disseminates, C. flocculosus, C. micaceus, C. radians and C. xanthothrix, three species of Coprinopsis viz C. atramentaria, C. insignis and C. semitalis and two species of Coprinus viz C. pinetorum and C. sterquilinus were identified. Among the species identified in this research, three unreported species from Iran namely C. insignis, C. semitalis and C. pinetorum are reported. Detailed morphological descriptions and illustrations of this three newly-recorded species were provided here and their evolutionary relationships were presented by the constructing of a phylogenetic tree.
Are XPD and XPG gene variants related to the mechanism of oral squamous cell carcinoma?
Authors: Avci Hakan , Iplik Elif Sinem , Aydemir Levent , Acar Senol , Kiyak Erkan , Unur Meral , Cakmakoglu Bedia
Published: February 2019

Oral cavity cancers have anatomically a big part of the body system and include several types of cancer. The aim of the study is to investigate the relation between XPG and XPD gene variants in the DNA repair system and oral squamous cell cancers. A total of 111 patients with a pathologic diagnosis of oral squamous cell carcinoma and a control group of 148 healthy volunteers who presented to Istanbul Faculty of Medicine, Department of Otolaryngology & Head and Neck Surgery and Dentistry Faculty were included in the study. Isolation of DNA was achieved using an Invitrogen Purelink Genomic DNA Kit. XPD alleles of Lys751Gln (rs13181) and XPG Asp1104His (rs17655) loci from genomic DNA samples were reproduced using polymerase chain reaction. A statistically significant difference in XPD genotype distribution between control and patient groups was determined (P=0.019). XPD Lys+ was significantly more common in the patient group than in the control group, and a two-fold increased risk for disease was determined. XPD Gln/Gln+ was significantly more common in the control group than in the patient group, and a two-fold decrease in risk for disease was determined (P=0.045). In the other region of the study, there was no statistically significant difference in terms of disease development between XPG genotypes. In conclusion, Lys751Gln polymorphism in the XPD gene could play a role in oral squamous cell development. It is important to increase the numbers of subjects in patient groups and healthy controls in studies to increase the possibility of determining XPD's potential as a molecular risk factor.
Bio-insecticidal effects of Oleaster leaves aqueous extracts against Psylla larvae (Euphyllura olivina (Costa)), a primary pest of Olea europaea L.
Authors: Mestar Nadjet G. , Boudiaf Malika N. , Lahcene Souad , Abbaci Hocine , Aiche Ghenima I. , Metna Boussad , Saadoun Noria S. , Taibi Faiza , Houali Karim
Published: February 2019

Many plant species produce phenolic compounds in their various organs and their use in crop protection. These plant secondary metabolites may serve as toxins against the insect pests. The objective of this study was to evaluate in vitro the bio-insecticidal effect of an aqueous extract of wild Olive leaves on Psylla larvae (Euphyllura olivina), a primary pest of the cultivated Olive tree (Olea europaea L. subsp sativa). Two concentrations of 0.05g/ml and 0.1g/ml leaves grinding powder in distilled water were sprayed on branches infested with Psylla larvae. The obtained results revealed a very significant mortality rate of the larvae 24 hours after spraying. The chemical composition of Oleaster leaves aqueous extracts is determined by HPLC-DAD. The results show in majority the presence of phenolic compounds represented by oleuropein and its metabolite hydroxytyrosol. The phenolic compounds of the crude extract were at the origin of this mortality. The Analysis of Variance revealed highly significant results both between the sampled trees and between the tested concentrations. The Principal Component Analysis (PCA) revealed a close relation between the physiological state of the studied trees and the degree of their infestation by the phytophagus. Taking into account, the physical and chemical characteristics of the sampled soils, data analysis showed that trees growing on nitrogen-rich soils were more infested than those growing on soils rich in organic carbon (Corg) and phosphorus (Porg).
Jezuicka ars educandi. Prace ofiarowane Księdzu Profesorowi Ludwikowi Piechnikowi SJ, Kraków 1995, ss. 288
Authors: D.Ź.-S. .
Published: February 2019

.
Stefania Walasek, Szkolnictwo średnie ogólnokształcące na ziemiach polskich w latach 1914-1923, Wydawnictwo Uniwersytetu Wrocławskiego, Wrocław 1996, ss. 26
Authors: Apanel Danuta
Published: February 2019

.
Ludzie, wydarzenia i ośrodki polskiej logopedii, „Logopedia” 23, Wydawnictwo Polskiego Towarzystwa Logopedycznego, Lublin 1996, ss. 246
Authors: Kuczyńska Ewa
Published: February 2019

.
Tadeusz Jałmużna, Z dziejów akademickiej Łodzi. Wyższa Szkoła Pedagogiczna 1946-1956, Wydawnictwo Uniwersytetu Łódzkiego, Łódź 1996, ss. 127
Authors: Schoener-Wojtowicz Małgorzata
Published: February 2019

.
XII Zjazd Szkoleniowo-Naukowy Logopedów
Authors: Kuczyńska Ewa
Published: February 2019

.
Problemy adaptacji młodego nauczyciela do zawodu w polskiej teorii i praktyce pedagogicznej okresu międzywojennego
Authors: Hellwig Jan
Published: February 2019

.
Polityka a wychowanie. Toruński ośrodek badań w dziedzinie historii wychowania
Authors: Strzelecki Michał
Published: February 2019

.
Juliusz Jundziłl, Rodzina rzymska w czasach prosperity i przemian ideowych II wieku. Apulejusz, Fronton, Marek Aureliusz i Tertulian, Wydawnictwo Wyższej Szkoły Pedagogicznej w Bydgoszczy, Bydgoszcz 1996, ss. 284
Authors: Jakubiak Krzysztof
Published: February 2019

.
Cele kształcenia w dydaktyce Drugiej Rzeczypospolitej i ich odbicie w niektórych programach nauczania dla szkoły ogólnokształcącej w latach 1920-1922
Authors: Rodek Violetta
Published: February 2019

Cele kształcenia w dydaktyce Drugiej Rzeczypospolitej i ich odbicie w niektórych programach nauczania dla szkoły ogólnokształcącej w latach 1920-1922
Konferencja naukowa „Funkcja społeczna prywatnych szkół średnich w II Rzeczypospolitej”. Augustów, 26-27 maja 2003 r.
Authors: Gulczyńska Justyna
Published: February 2019

.
Konferencja naukowa „Stan i potrzeby badań nad rozwojem oświaty, wychowania i kultury fizycznej w okresie PRL”. 8-9 września 2003 r.
Authors: Jankowiak Robert
Published: February 2019

.
II Międzynarodowa konferencja naukowa „Wielokulturowe środowisko historyczne Lwowa w XIX i XX wieku”. Uniwersytet Rzeszowski, 2 -3 października 2003 r.
Authors: Szulakiewicz Władysława
Published: February 2019

.
Profesor Józef Miąso - historyk wychowania i współtwórca Towarzystwa Historii Edukacji
Authors: Bartnicka Kalina
Published: February 2019

.
Ogólnopolski Konkurs Prac Magisterskich z Historii Edukacji. Nagroda im. Profesora Czesława Majorka
Authors: Ślączka Ryszard
Published: February 2019

.
Heliodor Święcicki (1854-1923) - pierwszy rektor Uniwersytetu Poznańskiego
Authors: Głowacka-Sobiech Edyta
Published: February 2019

Heliodor Święcicki (1854-1923) - pierwszy rektor Uniwersytetu Pozńskiego
Przed dwusetną rocznicą powstania Seminarium Nauczycielskiego Józefa Jeziorowskiego w Poznaniu
Authors: Fijałkowski Adam
Published: February 2019

Przed dwusetną rocznicą powstania Seminarium Nauczycielskiego Józefa Jeziorowskiego w Poznaniu
Działalność kobiet polskich na polu oświaty i nauki, pod redakcją Wiesława Jamrożka i Doroty Żołądź-Strzelczyk, Wydawnictwo Eruditus, Poznań 2003, ss. 250
Authors: Apanel Danuta
Published: February 2019

Działalność kobiet polskich na polu oświaty i nauki, pod redakcją Wiesława Jamrożka i Doroty Żołądź-Strzelczyk, Wydawnictwo Eruditus, Poznań 2003, ss. 250
Retoryka i historia w służbie wychowania w Polsce na podstawie analizy skryptu wykładów retoryki w Kolegium Jezuitów w Poznaniu z 1679 roku
Authors: Nowicki Michał
Published: February 2019

Rhetoric and History in the service of education in Poland on the basis of the script of rhetoric lectures at the College of the Jesuits in Poznan from 1679.The most important subject of the Old-Polish educational system was rhetoric, having roots in the tradition of the Ancient Rome. This statement is very important because of the fact of the orator’s moral and patriotic duties. Owing to this, the lessons’ focus was not only on technical aspects of rhetoric education but also on morality, religion and political knowledge. The article is divided into two main parts. First of them is describing the role of the rhetorical education and the evolution of the connection between rhetoric and history which existed from the 1st century A.D. until the first decades of the 18th century, when history started separating from rhetoric. The second part shows the historical education in practice on the example of the Jesuit College in Poznań. The analysis of this topic was based on the script of rhetoric lectures given in Poznań in 1679. With regard to this manuscript, it could be said that the most important aim of historical education was the patriotic and civil upbringing of the pupils, so that they could participate in political and cultural reality. The history taught in the College in Poznań was mainly connected with Poland and was rather practica