bluuebunny/crossref_metadata_2025 huggingface dataset:
Kütle ve Ağırlık Kavramlarının STEM Çemgisi ile Öğretimine Yönelik Bir Etkinlik Örneği
Authors: ŞENTÜRK ÖZKAYA Özge , BOSTAN SARIOĞLAN Ayberk
Published: June 2023

Bu çalışmanın amacı ‘Kuvvet ve Enerji’ ünitesinde yer alan kütle ve ağırlık kavramlarının STEM Çemgisi ile öğretimine yönelik bir etkinlik sunumudur. Çalışma Marmara bölgesindeki bir devlet okulunda öğrenim görmekte olan 27 yedinci sınıf öğrencisi ile yürütülmüştür. Etkinlik süresince sınıf altı gruba ayrılmıştır. Etkinlik dört ders saati süresince uygulanmıştır. Etkinlikte öğrenciler Tinkercad Web 2.0 aracını kullanarak modeller tasarlamış ve 3 boyutlu yazıcıda bu modelleri basmışlardır. Gruplar etkinlik süresince STEM çalışma yapraklarını doldurmuşlardır. STEM çalışma yapraklarından elde edilen verilerin analizinde ise “STEM Çalışma Yaprağı Değerlendirme Rubriği” kullanılmıştır. Çalışma yapraklarının analizinden elde edilen bulgularda bütün grupların model tasarladığı belirlenmiş ancak tasarladıkları modeli kullanarak sunulan problemi çözmede grupların çoğunlukla kısmen yeterli oldukları görülmüştür. Öğrencilerin model tasarlama ve bu modelleri kullanarak problem çözme becerilerini arttırmaya yönelik farklı çalışmalar da yapılabilir.
The Impact of Carbon And Energy Prices on The Return of Energy Sector Stock in Selected Asia-Pacific Countires
Authors: Almas Mawhibah Hasan , Rizal Nora Amelda , Kusairi Suhal
Published: June 2023

The stock market is very important in the country's economy, namely as a source of corporate funding and especially in investments that have the aim of increasing the welfare of investors and companies. The purpose of this study is to analyze the effect of the rate of return on carbon costs, Brent crude oil, palm oil, interest rates, and exchange rates on the rate of return on energy stock prices in Asia-Pacific countries from 1st January 2016 to end of December 2021. In this study, the phenomena were explored utilizing quantitative approaches to collect data and test previously determined hypotheses. The panel data model is used, as well as the VECM (Vector Error Correlation Model) test. The results show that the influence of CO2 return on energy sector returns is negative in the short term but positive in the long term. Return on energy industry and return on Brent oil have both short-term and long-term unfavorable effects. The return of the use of palm oil has an advantageous long-term and short-term impact on the energy industry's return. The exchange rate has only a short-term negative relationship with the return of energy. Lastly, there is no long-term or short-term correlation between interest rates and the return on energy. The implication of this result is that industries must switch to using environmentally friendly devices and governments must declare regulations to emitters producers.
Using Machine Learning to Predict Cost Overruns in Construction Projects
Authors: Theingi Aung  , Liana Sui Reng , Htet Arkar , Amiya Bhaumik
Published: June 2023

Addressing the persistent issue of cost overruns in construction projects, our study explores the potential of machine learning algorithms for accurately predicting these overruns, utilizing an expansive set of project parameters. We draw a comparison between these innovative techniques and traditional cost estimation methods, unveiling the superior predictive accuracy of machine learning approaches. This research contributes to existing literature by presenting a data-driven, reliable strategy for anticipating and managing construction costs. Our findings have significant implications for project management, offering a path towards more efficient and financially sound practices in the construction industry. The improved prediction capabilities could revolutionize cost management, facilitating better planning, risk mitigation, and stakeholder satisfaction.
Cardiovascular risk management in the peri‐operative setting
Authors: Mahendran Shehane , Thiagalingam Aravinda , Hillis Graham , Halliwell Richard , Pleass Henry CC , Chow Clara K
Published: June 2023

Peri‐operative cardiovascular events occur in up to 3% of patients undergoing non‐cardiac surgery.

Accurate cardiovascular risk assessment is important in the peri‐operative setting, as it allows informed and shared decisions regarding the appropriateness of proceeding with surgery, guides surgical and anaesthetic approaches, and may influence the use of preventive medications and post‐operative cardiac monitoring. Quantitative risk assessment may also inform a reconsideration of choosing a more limited lower risk type of surgery, or conservative management.

Pre‐operative cardiovascular risk assessment starts with clinical assessment and should include an estimate of functional capacity.

Specialised cardiac investigations are rarely indicated specifically to assess pre‐operative cardiovascular risk. The decision regarding cardiac investigations is influenced by the nature, extent and urgency of surgery.

The strategy of performing pre‐operative revascularisation to improve post‐operative outcomes is not evidence‐based and recent international guidelines recommend against this.
The health care and societal costs of inherited retinal diseases in Australia: a microsimulation modelling study
Authors: Schofield Deborah , Kraindler Joshua , Tan Owen , Shrestha Rupendra N , West Sarah , Hart Natalie , Tan Liny , Ma Alan , Grigg John R , Jamieson Robyn V
Published: June 2023

Objectives

To estimate the health care and societal costs of inherited retinal diseases (IRDs) in Australia.

Design, setting, participants

Microsimulation modelling study based on primary data — collected in interviews of people with IRDs who had ophthalmic or genetic consultations at the Children's Hospital at Westmead or the Save Sight Institute (both Sydney) during 1 January 2019 – 31 December 2020, and of their carers and spouses — and linked Medicare Benefits Schedule (MBS) and Pharmaceutical Benefits Schedule (PBS) data.

Main outcome measures

Annual and lifetime costs for people with IRDs and for their carers and spouses, grouped by payer (Australian government, state governments, individuals, private health insurance) and type (health care costs; societal costs: social support, National Disability Insurance Scheme (NDIS), income and taxation, costs associated with caring for family members with IRDs); estimated annual national cost of IRDs.

Results

Ninety‐four people (74 adults, 20 people under 18 years; 55 girls and women [59%]) and 30 carers completed study surveys (participation rate: adults, 66%; children, 66%; carers, 63%). Total estimated lifetime cost was $5.2 million per person with an IRD, of which 87% were societal and 13% health care costs. The three highest cost items were lost income for people with IRDs ($1.4 million), lost income for their carers and spouses ($1.1 million), and social spending by the Australian government (excluding NDIS expenses: $1.0 million). Annual costs were twice as high for people who were legally blind as for those with less impaired vision ($83 910 v $41 357 per person). The estimated total annual cost of IRDs in Australia was $781 million to $1.56 billion.

Conclusion

As the societal costs associated with IRDs are much larger than the health care costs, both contributors should be considered when assessing the cost‐effectiveness of interventions for people with IRDs. The increasing loss of income across life reflects the impact of IRDs on employment and career opportunities.
Prevalence of Orthopedic Pains in Children and Adolescents: A Systematic Review and Meta-analysis
Authors: Karimiyarandi Hosein , Khalilizad Majid
Published: June 2023

Context: Musculoskeletal disorders are among the main causes of death and disability and can impose high costs on individuals and countries. Considering the importance of pain, the present meta-analysis study aimed to investigate the prevalence of orthopedic pains in Iranian children and adolescents. Methods: The present study was reported in line with PRISMA. The searching process was carried out using keywords, including adolescents, pain, youth, school-age children, shoulder pain, neck pain, shoulder, and neck, AND/OR operators for the articles published during 2000 and 2022 in Scopus, Embase, PubMed, Scientific Information Database, Magiran, International Statistical Institute, and Islamic World Science Citation Center databases. This study reviewed the articles that reported the prevalence of orthopedic pains (i.e., wrists/hands, shoulders, elbows, and knees) among the 5-18-year age group in Iran and extracted their results. Two researchers conducted the search quite independently and extracted the necessary data using a researcher-made checklist. The collected data were analyzed using Comprehensive Meta‐Analysis software (CMA3). Results: Initially, 418 articles were identified, and 14 articles were entered into the systematic review stage. The prevalence rates of pains related to wrists/hands, shoulders, elbows, and knees were 6.6 (95% confidence interval [CI]: 3.2 - 13.0), 26.9 (95% CI: 17.0 - 39.7), 2.9 (95% CI: 1.3 - 6.3), and 6.6 (95% CI: 3.0 - 14.2), respectively. Conclusions: The prevalence of shoulder and knee pains in individuals under 18 years in Iran was high. Therefore, it is necessary to make necessary interventions and take preventive measures.
Investigating the Presence of Efflux Pump Genes adeI and adeJ in Clinical Antibiotic-Resistant Isolates of Acinetobacter baumannii
Authors: Ghafari Samaneh , Mirnejad Reza , Sameni Fatemeh , Dehghan-Tarazjani Mohamad Hoseyn , Khaledi Mansoor , Niakan Mohammad
Published: June 2023

Background: Acinetobacter baumannii is one of the most important known causes of hospital infections worldwide that is resistant to many common antibiotics. Efflux pumps are among the main reasons behind resistance in this bacterium. Objectives: This study was conducted to investigate the presence of efflux pump genes (adeI, adeJ) in clinical antibiotic-resistant isolates of A. baumannii in Tehran hospitals. Methods: One hundred fifty clinical samples of wounds, urine, sputum, and blood were collected periodically (6 months) from Tehran hospitals. Acinetobacter baumannii was identified using common biochemical methods. After conducting biochemical tests, the final confirmation of the samples was performed by examining the blaOXA-51-like gene by molecular polymerase chain reaction (PCR) method. The disk diffusion antimicrobial susceptibility testing was performed using Mueller Hinton agar growth medium according to Clinical and Laboratory Standards Institute (CLSI) guidelines on nine antibiotics. Then the samples were investigated for the presence of adeI and adeJ genes. Results: Examining the antibiotic resistance of the isolates showed that the resistance level varied from 48.1% to 98.2%, depending on the antibiotic type. In this study, isolates showed the highest and lowest resistance to tetracycline and gentamicin, respectively. Also, positive isolates for the presence of adeI and adeJ genes showed the highest resistance to tetracycline, amikamycin, ceftazidime, and ceftriaxone. Isolates that were negative for the presence of these two genes showed the highest sensitivity to imipenem, gentamicin, and ciprofloxacin. Conclusions: In this study, the correlation of antibiotic resistance test and PCR results showed that the presence of adeI and adeJ genes in the samples significantly increased the resistance to all investigated antibiotics. Therefore, evaluating efflux pumps proves to be useful in identifying antibiotic-resistant strains and appropriate drug treatment. Of course, the role of other factors in creating resistance should not be neglected.
The Role of Physiology, Affect, Behavior and Cognition in Leader Character Activation: A Music Intervention
Authors: Crossan Mary , Ellis Cassandra , Crossan Corey
Published: June 2023

We build on the theoretical model proposed by Crossan et al. (2021) to examine leader character activation, through the use of music, as a foundational area for leader character development. Our findings reveal that music influences all of the physiology, affect, behavior, cognitive (PABC) systems to more and less degrees. As well, music activates all dimensions of character, with different dimensions of character varying in their reliance on the PABC systems. Our empirical examination underscores the importance of examining activation as an initial step in development, yielding insights into the holistic role of the PABC systems in character development. Although all four systems are implicated, this study points to the need to understand how various dimensions of leader character rely differentially on the PABCs, which provides important insight into how leader character development can be tailored. Finally, the study verifies the important role of music therapy in the activation and subsequent development of leader character and paves the way for other innovative approaches that move beyond the cognitive and behavioral focus in leadership development to embrace physiology and affect as well.
We Don’t Do that Here: Using Role Playing and Character Battle Drills to Develop Upstander Behavior at West Point
Authors: Spain Everett S. , Konheim-Kalkstein Yasmine L. , Erbe Ryan G. , Wilsey Corrine N. , Rosenberg Stacey F.
Published: June 2023

Background: The Army is focused on the prevention of harmful interpersonal behaviors such as sexual harassment and sexual assault. Training soldiers who may witness these behaviors to intervene is considered paramount to the Army’s prevention efforts. Objective: To increase the propensity and efficacy of cadets (undergraduate college students) employing upstander behaviors when witnessing harmful interpersonal behaviors in less governed spaces, the United States Military Academy at West Point facilitated two scenario-based role-playing workshops to develop its cadets while piloting new methods of training intervention behaviors. Methods: Both workshops had cadets improvise roles as upstanders, perpetrators, victims, and witnesses. The first workshop focused on developing cadets’ propensity (courage) to intervene and intentionally provided cadets with little guidance on if and how they should intervene, allowing them to develop their own workable intervention strategies and skills. The second workshop focused on developing cadets’ effectiveness during an intervention by having them apply the new Character Battle Drill (CBD) concept, which is a specific sequence of action steps to follow, including specific scripts to say during an intervention. Results: In both workshops, cadets reported higher levels of engagement than traditional forms of bystander training. Conclusions: Improvisational role playing seems promising for future training. Lessons-learned, limitations, and areas of future research are discussed.
New Challenges to Character Education
Authors: Aspray Barnabas
Published: June 2023

The recent growth of character education worldwide has met with a number of criticisms. This article applies a humanities methodology to investigate three of these criticisms in the belief that a growing movement can only benefit from attention to its critics. The first criticism is that character education depends on flawed or unreliable social science methods. In response, the article recommends more focused attention on the philosophical foundations of empirical research on character. The second criticism is that character education leaves unjust systems unchallenged. In response, the article recommends increased academic dialogue between character education discourse and social justice discourse. The third criticism is that character education violates the purpose of a university. In response, the article denies the objection, appealing to historical and philosophical sources to argue that character has been and should be at the heart of all Higher Education.
Reproductive Justice as Reparative Justice
Authors: Valentine Desiree ,   Philosophy Documentation Center
Published: June 2023

While the principles of reproductive justice are generally agreed upon in progressive reproductive political circles, other theoretical frameworks such as reparative justice can further foster the goals of the movement. In the literature, however, reparative justice has been insufficiently explored as it relates to reproductive injustice. My concern in this essay is therefore the development of conceptual architecture for understanding reproductive justice as reparative in nature. A reparative approach to reproductive ethics importantly takes up the demand to situate reproduction within ongoing historical and sociopolitical contexts. It makes transparent the harms generated by an oppressive social order and the depths to which conditions must change for reproductive justice to emerge. To construct the relationship between reparative and reproductive justice, I employ Olúfemi Táíwò’s constructivist view of reparations as an ongoing, generative, and ultimately world-building project. For, if reproductive justice is about developing enabling conditions wherein folks can control their birthing options and parent in safe and healthy environments, then a constructivist reparative approach is necessary—one which takes seriously the accumulative harms of history and their relation to transforming social structures in the present.
Pendidikan Multikultural dalam Usaha Meningkatkan Kesadaran HAM di Sekolah
Authors: Putri Shanas Septina , Tiodora Lucia , Sukmawati Anis
Published: June 2023

Multicultural education plays an important role in raising issues of mutual freedom (HAM) in schools. Through this method, students and school staff are welcome to appreciate and understand societal, racial, religious, and social diversity. Multicultural education helps combat the divisions, generalizations, and foul play that may arise in an instructive climate. Students can cultivate empathy and gain a deeper understanding of other people's points of view by studying other people's cultures and experiences. This contributes to the development of an inclusive school environment where every individual is treated with dignity and respect. Students' perceptions, attitudes, and actions regarding human rights can also be changed through multicultural education. The understanding that everyone has the same rights to be respected, recognized, and treated fairly is taught to students. They also learn about the importance of opportunities for articulation, the right to training, and other basic freedoms. The school creates an atmosphere that encourages equality, fairness, and respect for differences by implementing multicultural education. This not only makes people more aware of human rights but also helps shape a generation of students who are more tolerant, open, and ready to face an increasingly diverse world.
FAKTOR PENYEBAB DAN UPAYA PENANGGULANGAN TINDAK PIDANA PENCABULAN ANAK OLEH AYAH KANDUNG DI WILAYAH HUKUM KEPOLISIAN SEKTOR KELAPA LIMA
Authors: Bandi Melan , Petrus Leo Rudepel , Manu Nikolas
Published: June 2023

Penelitian ini bertujuan untuk menganalisis faktor penyebab tindak pidana pencabulan anak oleh ayah kandung di wilayah hukum Kepolisian Sektor Kelapa Lima serta mengidentifikasi upaya penanggulangan yang dapat dilakukan. Penelitian ini menggunakan pendekatan hukum empiris dengan mengumpulkan data melalui wawancara terhadap 2 orang responden/informan. Data yang digunakan adalah data primer dan sekunder yang diperoleh melalui wawancara dan studi pustaka, kemudian dianalisis secara deskriptif kualitatif. Hasil penelitian menunjukkan bahwa faktor-faktor penyebab tindak pidana pencabulan terhadap anak oleh ayah kandung di wilayah hukum Kepolisian Sektor Kelapa Lima meliputi: (1) rendahnya pendidikan yang mengakibatkan kurangnya pemahaman terhadap dampak perbuatan tersebut, (2) lingkungan tempat tinggal yang sepi, (3) penyalahgunaan minuman keras (beralkohol), dan (4) penyalahgunaan teknologi (HandPhone). Dalam penanganan kasus kejahatan pencabulan oleh ayah terhadap anak kandungnya, perlu dilakukan dengan perhatian khusus. Perlakuan yang buruk terhadap anak, terutama anak perempuan, dapat berdampak negatif pada tumbuh kembang mereka. Oleh karena itu, penanganan kasus ini perlu mendapatkan perhatian serius agar mental dan pikiran anak tidak terganggu dan tidak membawa dampak traumatis serta negatif kepada orang lain
PENEGAKAN HUKUM TERHADAP PELAKU TINDAK PIDANA PEMALSUAN MATA UANG ATAU UANG KERTAS DI KELURAHAN LAI-LAI BESI KOPAN, KECAMATAN KOTA LAMA, KOTA KUPANG
Authors: Gara Sawo Wilibrodus , S.M. Kadja Thelma , A. Kian Darius
Published: June 2023

Pemalsuan uang banyak terjadi pada uang kertas dilakukan dengan berbagai cara. Kegiatan pemalsuan uang dinilai sangat merugikan terutama untuk kepentingan umum. Pelaku yang melakukan kegiatan pemalsuan uang dapat diberikan hukuman dan perbuatan tersebut masuk ke dalam tindak pidana. Studi ini bertujuan untuk mengetahui menyebabkan tindak pemalsuan mata uang atau uang kertas dan penegakan hukum pidana terhadap pelaku pemalsuan mata uang atau uang kertas serta upaya penanggulangan tindak pidana pemalsuan mata uang atau uang kertas di Kelurahan Lai-lai Besi Kopan, Kecamatan Kota Lama, Kota Kupang. Penulis ingin mengkaji dan meneliti secara mendalam bagaimana penegakan hukum pidana terhadap pelaku tindak pidana pemalsuan mata uang atau uang kertas. Jenis  penelitian yang digunakan yaitu menggunakkan penelitian yuridis empiris dengan menggunakan pendekatan kasus. Informan dalam penelitian ini yakni penyidik dari Polsek Kelapa Lima. Sumber data yang digunakan adalah data primer dan data sekunder. Teknik pengumpulan data yang digunakan adalah wawancara dan studi kepustakaan. Hasil penelitian ini menunjukan bahwa Penegakan Hukum Terhadap Pelaku Tindak Pidana Pemalsuan Mata Uang Atau Uang Kertas Di Kelurahan Lai-Lai  Besi Kopan, Kecamatan Kota Lama Kota Kupang yaitu : penegakan hukum tidak dilaksanakan sesuai dengan amanat perundang- undangan, bahwa perbuatan terdakwa merupakan pengulangan tindak pidana pemalsuan uang atau residive, namun pada isi putusan akhir peerkara pada sidang Pengadilan Negeri Kupang tidak menjatuhkan hukuman yang memberatkan terdakwa sehingga perlu diperhatikan pula rumusan pasal 486 KUHP dan terdakwa melakukan dua tindak pidana yakni memalsukan mata uang atau uang kertas dan tindak mengedarkan serta membelanjakan uang palsu tersebut namun hanya dijatuhkan hukuman atas tindak pemalsuan mata uang atau uang kertas. Sehingga belum sesuai dengan Pasal 244 KUHP. Sehingga berdasarkan teori yang dikemukakan oleh Satjipto Raharjo (2000;175-183) tentang penegakkan hukum pada Pengadilan Negeri Kupang tidak melaksanakan hukum secara konkrit dalam kehidupan masyarakat dan tidak menjatuhkan hukuman yang dapat memberi efek jera kepada pelaku tindak pidana
Under the sign of pandemic
Authors: Scrumeda Andreea
Published: June 2023

The present paper aims to chronologically and comparatively present the evolution of human behavior, from the first recorded pandemics to the Covid-19 pandemic. We are interested in the attribution of these infectious disease’s origin, as well as in the literary and artistic manifestations that represented these disasters. While in the Antiquity the pagan philosopher Porphyry of Tire lamented the rise of Christianity, blaming it for the appearance of the plague, in Middle Ages Europe, Christians looked for scapegoats among the religious minorities. Epidemics and pandemics also proved to be an irresistible subject for many writers; in visual arts, the Great Plague of the Middle Ages inspired the iconographic theme Danse Macabre. Today, movies deal with this topic from an apocalyptic perspective, thus marking a return to the ancient conceptions of plagues. We also find that, from the Middle Ages to the present day, the popular reactions are broadly the same, including negationism, misinformation and mistrust of authorities. Apart from questionable cures, the tendency to reject sanitary measures has also been survived, especially since social media currently provide a huge amount of right and of false information, hard to classify.
Desconexión moral y social en un programa del Estado sobre la inserción laboral a víctimas de violencia familiar en el distrito Ventanilla – Callao, Perú en 2022
Authors: Panta Ymàn María Esther
Published: June 2023

La investigación tiene como objetivo valorar en un programa del Estado, la inserción laboral a víctimas de violencia familiar, distrito Ventanilla Callao - 2022. Para cumplir con tal finalidad nuestra investigación desarrollo el enfoque cuantitativo, haciendo uso del instrumento de la técnica para recolectar información, para ello se realizó mediante el instrumento de cuestionario.El estudio de investigación se conforma con una muestra de 381 profesionales de la especialidad de psicología, de instituciones públicas que brindan asistencia a víctimas de violencia familiar implicados en procesos judiciales. Entre los resultados obtenidos se observa que sí existen diferencias significativas, como consecuencia de la prueba de hipótesis, explicado que las características sociolaborales para la inserción laboral ayudan a víctimas de violencia familiar, en un programa del Estado, distrito de Ventanilla Callao – 2022.
Organization Citizenship Behavior: Mediation towards Leadership Styles and Employees Engagement at Workplace in healthcare through the Lens of Social Exchange Theory
Authors: Kundi Ghulam Muhammad , Dr. Purshottam Manipal
Published: June 2023

This research study explores the role of OCB on leadership and employee engagement. The aims of the study was to investigate the mediating role of organization citizenship behavior on the leadership styles and employees’ engagement at work place in health organizations through the lens of social exchange theory. A structured questionnaire has been prepared strictly in line with the extracted variables and guidelines for questionnaire construction. The primary data was collected through a closed-ended questionnaire, distributed among healthcare professionals in Lady Reading Hospital Peshawar and Shifa International Hospital Islamabad. The Bivariate correlation and multiple regressions were used in this study and the result shows a significant relationship between variables. The study found partial mediation between variables during analysis. Yet, the results and findings are only valuable for Pakistani healthcare institutions because data was collected from public and private sector hospitals in Peshawar and Islamabad.
Restrição do uso das águas da bacia hidrográfica do rio Matipó devido à contaminação microbiológica
Authors: Reis Deyse Almeida dos , Nascimento Laura Pereira do , Marques Lilian de Souza , Oliveira Edilson Gonçalves de , Ferreira Clóvis de Souza , Chagas Igor Aparecido Santana das , Roeser Hubert Mathias Peter , Santiago Aníbal da Fonseca
Published: June 2023

O presente estudo foi realizado na bacia hidrográfica do Rio Matipó, um afluente do Rio Doce, em Minas Gerais – Brasil. O principal objetivo foi avaliar a contaminação microbiológica das águas da bacia devido à influência da atividade humana. Para tal, foram realizadas amostragens de água em 25 estações de monitoramento situadas ao longo do curso hídrico em períodos sazonais distintos. Essas amostragens possibilitaram mensurar variáveis químicas e microbiológicas das águas. A análise dos dados obtidos permitiu observar a limitação dos usos da água da bacia hidrográfica pelo fato de estar contaminada com microrganismos, alguns potencialmente patogênicos. Os impactos ambientais verificados na bacia hidrográfica, como criação de animais nas margens e, principalmente, lançamento de esgoto sanitário sem tratamento, foram os principais fatores que interferiram na limitação dos usos da água para balneabilidade e para o abastecimento público.

Keywords: Contamination, E. coli, Sewage, Doce River

 

 Abstract

The present study wascarried outin the Matipó river watershed, a tributary of the Doce river, in Minas Gerais,Brazil. The main objective was to evaluate the microbiological contamination of waters of the basin due to the influence of human activities. In order to do so, water sampling was  performed  in  25  sampling  stations  along  the water course in distinctseasonal  periods. These samples made it possible to measure chemical and microbiological variables of the waters. The analysis of the obtained data allowed to noticethe limitation of the water uses inthe watershed due to contamination withmicroorganisms, some potentially pathogenic. The environmental impacts observed in the watershed, such as livestock famingon the banks and mainlythe release of untreated domestic sewage were the main factors that interfered with the limitation of water usefor leasure purposes and public supply.
Expediente
Authors: Editorial Equipe
Published: June 2023

Expediente do n.1, v. 1 da Revista Mineira de Recursos Hídricos (RMRH).
Análise do comportamento das vazões nas bacias dos rios Paraopeba e Velhas
Authors: Fraga Micael de Souza , Ribas Luiza Pinheiro Rezende
Published: June 2023

O presente estudo teve como objetivo caracterizar o comportamento das vazões nas bacias hidrográficas dos rios Paraopeba (SF3) e Velhas (SF5), analisando a ocorrência de eventos extremos de máxima e mínima, bem como as tendências das séries históricas de vazões. Para isso, as séries históricas de vinte e uma estações fluviométricas presentes nas bacias foram analisadas. Foram determinadas as seguintes vazões: média de longa duração (Qmld) e mínima média de sete dias consecutivos, associada a um período de retorno de 10 anos (Q7,10). Posteriormente, foi avaliado o período chuvoso referente ao ano hidrológico de 2019/2020, bem como a ocorrência de vazões abaixo da Q7,10 para os anos de 2019 e 2020. Por fim, foi avaliada a estacionariedade dos dados de vazão utilizando o teste de Pettitt e a correlação de Spearman. Os resultados mostraram que o ano hidrológico pode ser definido de outubro a setembro, em ambas as bacias hidrográficas avaliadas. O período chuvoso do ano hidrológico de 2019/2020 foi caracterizado pelos altos valores de vazão nos cursos d’água, apresentando os maiores valores de vazão já registrados em algumas estações. Na bacia do rio Paraopeba foi observado significativas condições de restrição efetiva de uso dos recursos hídricos no ano de 2019, com menores ocorrências na bacia do rio das Velhas. Com a análise das tendências foi possível observar que o período seco tende a se intensificar nas bacias do rio Paraopeba e rio das Velhas.

Keywords: Water  demand,  Stationarity, Extreme  events, Belo  Horizonte Metropolitan  Area (RMBH)

 

Abstratc 

The purpose  of  the present  study is to  characterize  the  behavior  of  the flow in  the basins of  Paraopeba (SF3) and Velhas (SF5) rivers, analyzing the occurrence of extreme maximum and minimum events, as well as the trends of the historical flow series. For that, the historical series of twenty-one stream gauge stations present in the basins were analyzed. The following flows were determined: long-term average (Qmld) and average minimum of seven consecutive days, associated  with  a  10-year return period  (Q7.10).  Subsequently,  the  rainy  period  for  the hydrological year 2019/2020 was evaluated, as well as the occurrence of flows below Q7.10 for the  years  2019  and  2020.  Finally,  the  stationarity  of  the  flow  data  was  evaluated  using  the Pettitt test and Spearman's correlation. The results showed that the hydrological year can be defined from October to September, in both analyzed basins. The rainy period of the 2019/2020 hydrological year was characterized by high flow rates in water courses, reaching the highest flow rates  ever  recorded  in  some stations.  In  the  Paraopeba basin,  significant  conditions  of effective  restriction  in  the  use  of  water  resources  were  observed  in  2019,  with  lower occurrences in the Velhas basin. With the analysis of the trends it was possible to observe that the dry period tends to be intensified in the basins of Paraopeba and Velhas rivers.
Segurança hídrica em tempos de pandemia de Covid-19
Authors: Cerezini Monise Terra
Published: June 2023

A segurança hídrica é o objetivo central da Política Nacional de Recursos Hídricos no Brasil e considera as dimensões humana, econômica, ecossistêmica e de resiliência, sendo compreendida como a garantia de acesso a água em termos de quantidade e qualidade adequados para abastecimento, alimentação, preservação de ecossistemas e demais usos, considerando os riscos em nível aceitável para as pessoas, economias e meio ambiente. A pandemia provocada pelo novo Coronavírus e o consequente isolamento social e desaceleração econômica acentuou ainda mais as desigualdades sociais brasileiras. Nesse sentido, a segurança hídrica é questão fundamental para alcançar o acesso universal a serviços de oferta de água, indispensáveis para prover meios de subsistência fundamentais para manter a qualidade de vidas dos seres humanos.

Keywords: Water security, Pandemic, COVID-19

 

Abstratc

Water security is a central issue of Water Policy in Brazil and considers the human, economic, ecosystem and resilience dimensions. This concept is understood as the guarantee of access to water in terms of adequate quantity and quality for supply, food, preservation ecosystems and other uses, considering risks at an acceptable level for people, economies and the environment. The pandemic caused by the new Coronavirus and the resulting social isolation and economic slowdown further accentuated brazilian social inequalities. In this sense, water security is a fundamental issue in order to achieve universal access to water supply services, which are essential to provide basic means of subsistence to maintain the life quality of human beings and ecosystems.
Editorial
Authors: Júnior José Alves Junqueira
Published: June 2023

Editorial do v.1, n. 2 da Revista Mineira de Recursos Hídricos (RMRH).
Análise do impacto na qualidade da água do rio Paraopeba após 2 ciclos hidrológicos do rompimento das barragens de rejeitos da mineradora Vale S.A
Authors: Fernandes Antoniel Silva , Santos Matheus Duarte , Nogueira Patrícia Franklin Mayrink , Saraiva Vanessa Kelli , Oliveira Vitor Faria de Carvalho , Almeida Katiane Cristina de Brito , Nacif Wanderlene Ferreira , Fonseca Marcelo da
Published: June 2023

A presente nota técnica científica tem por objetivo avaliar a qualidade das águas do rio Paraopeba, impactados pelos rompimentos das barragens de rejeito, provenientes da Mina de Córrego do Feijão, da mineradora Vale S.A., em Brumadinho, Minas Gerais, decorridos dois ciclos hidrológicos. O monitoramento mostrou que o trecho de aproximadamente 40 km de extensão (distância medida desde as barragens que romperam), entre os municípios de Brumadinho e São Joaquim de Bicas, foi totalmente impactado, inviabilizando o uso da água. Nos três últimos períodos sazonais (período seco/2020, períodos chuvoso e seco/2021), observa-se que os valores de turbidez, manganês, ferro e chumbo ainda permanecem acima dos limites de Classe 2. Contudo, os registros desses parâmetros já se aproximam dos valores da série histórica do Igam, do período pré-rompimento ao longo da calha do rio Paraopeba.

Keywords: Dam rupture. Water quality. Paraopeba River.

 

Abstract

The present scientific note aimed to assess water quality in the Paraopeba River, impacted by tailings released from the ruptured of Córrego do Feijão Dam (Brumadinho, Minas Gerais), in two  hydrological  cycles.  The results  demonstrated  impacts  on  water  supply  for  the municipalities provided by the Paraopeba River, aproximately 40 km of extension from dam rupture, between Brumadinho and São Joaquim de Bicas. Over the last three seasonal periods (january/2020  to  april/2021), concentration  of  turbidity, manganese, iron and lead above legislation limits were perceived. Nevertheless, these concentrations are already near to what had been noticed previously, according to the historical series in Paraopeba River recorded by Igam (Minas Gerais Water Management Institute) before the dam rupture.
Thick‐Network Electrode: Enabling Dual Working Voltage Plateaus of Zn‐ion Micro‐Battery with Ultrahigh Areal Capacity
Authors: Wu Yudong , He Ningning , Liang Guojin , Zhang Chaofeng , Liang Changhao , Ho Derek , Wu Mingzai , Hu Haibo
Published: June 2023

Aqueous Zn‐ion micro‐batteries (AZMBs) have been recently shown to be promising integrated and safe micropower sources for portable electronics but with wide commercial adoption greatly constrained by their relatively low areal capacity. Although increasing the electrode thickness is proposed, the performance is compromised due to sluggish reaction kinetics, slow ion diffusion rate, and underutilization of active materials. Herein, the technique of utilizing a 3D thick‐network electrode, consisting of closely interweaved MnO2 nanowires (MnO2 NWs), silver nanowires (AgNWs), and carbon nanotubes (CNTs) is presented. The technique readily enables electrode realization up to a thickness of 351 µm, where the porous structure, high hydrophilicity, and fast electrolyte infiltration jointly contribute to fast kinetics. Matching with a Zn metal anode, the prototyped AZMBs acquire an ultra‐high areal capacity/power density of 809 µAh cm−2/1951 µW cm−2. Additionally, as MnO2 NWs and AgNWs collectively participate in the reaction as active substances, the AZMBs deliver dual voltage plateaus to further improve the areal energy density, realizing a maximum value of 896 µWh cm−2. The 3D thick‐network electrode supporting dual working voltage plateaus can provide a path forward for developing AZMBs with simultaneously ultra‐high areal capacity and energy density.
A Dual Heat Shock Protein Down‐Regulation Strategy Using PDA/Cu/ICG/R Controlled by NIR “Switch” Enhances Mild‐Photothermal Therapy Effect
Authors: Ding Xin , Wang Tianyu , Bai Shiwei , Yang Mian , Peng Na , Qiu Tao , Liu Yi
Published: June 2023

The purpose of this study is to down‐regulate heat shock proteins and improve the mild photothermal therapy (mild‐PTT) effect of polydopamine (PDA) by preparing the nanosystem of Cu2+ and indocyanine green (ICG)–loaded PDA nanospheres with surface modification of integrin‐targeted cyclic peptide (cRGD) (PDA/Cu/ICG/R), which can limit ATP synthesis through the double mitochondrial destruction pathway. In vitro and in vivo experiments using PDA/Cu/ICG/R irradiated with an NIR laser demonstrate that when NIR is “OFF,” Cu2+ can undergo Fenton‐like reaction in tumor cells, producing a large amount of hydroxyl radicals (·OH), which leads to oxidative stress in cells. This oxidative stress can cause mitochondrial oxidative phosphorylation dysfunction, resulting in limited ATP synthesis. When NIR is “ON,” mild‐PTT can accelerate Cu2+ to produce ·OH. Simultaneously, NIR can activate ICG to produce reactive oxygen species (ROS) storm, amplify intracellular oxidative stress, and continuously damage mitochondria. The biodegradability of PDA greatly reduces the risk of toxicity caused by long‐term retention of PDA/Cu/ICG/R in organisms. Finally, the improvement of the mild‐PTT effect of PDA is successfully achieved through the double mitochondrial destruction pathway of Cu2+ and ICG controlled by NIR “switch.”
Transition Metal‐FreeO‐Arylation ofN‐Alkoxybenzamides Enabled by Aryl(trimethoxyphenyl)iodonium Salts
Authors: Elboray Elghareeb E. , Bae Taeho , Kikushima Kotaro , Kita Yasuyuki , Dohi Toshifumi
Published: June 2023

Herein, we develop a metal catalyst‐free protocol forO‐arylation of benzamide hydroxamate esters. The chemoselectiveO‐versus N‐arylation of the amides was tuned by varying the electronic and/or steric properties of the diaryliodonium salt and/or the substrate. TheO‐arylation reaction would preferentially occur for sterically and electronically diverse substrates. This study, which reveals the possibility of substituent‐ and reagent‐controlled chemoselectivity, with diaryliodonium salts might attract interest in the area of hypervalent iodine chemistry.
Alternatives for sustainable weed control in single‐ and double‐cropped soybean: A case study for Mediterranean irrigated conditions
Authors: Simon‐Miquel Genís , Reckling Moritz , Recasens Jordi , Plaza‐Bonilla Daniel
Published: June 2023

The irrigated cropping systems in South Europe could benefit from soybean [Glycine max (L.) Merr.] introduction in their maize (Zea mays L.)‐based crop rotations. However, sustainable weed management strategies are needed for soybean growers under Mediterranean irrigated conditions. This work aimed to assess the weed control efficacy, and the soybean performance, of alternative management practices for single‐ and double‐cropped soybean. Two field experiments were carried out in northeast Spain in the period 2019–2021. Row width narrowing (75–37.5 cm), herbicide application (yes/no), and roller‐crimped rye [Secale cereal (L.) M.Bieb.] cover crop (yes/no) were assessed in the single cropping system experiment (SCS). In the barley‐soybean double cropping system experiment (DCS), row width narrowing and herbicide application were assessed. In the SCS, the presence of rye cover crop reduced weed biomass up to 92% compared to the controls without herbicide and cover crop in 2020. In 2021, no effect of the cover crop on weed pressure was found due to the low amount of rye biomass accumulated (11.8 and 3.4 ton DM ha−1 in 2020 and 2021, respectively). In the DCS, herbicide application attained the expected weed control. Row width narrowing to 37.5 cm did not have an impact on weed pressure nor on soybean yield in either experiment. We concluded that herbicide reduction for single‐cropped soybean under Mediterranean irrigated conditions can be achieved by roller‐crimping a rye cover crop, provided enough rye biomass is accumulated. In the DCS, our results indicated that further research is needed to find alternatives to chemical weed control.
Inflammatory characteristics of central compartment atopic disease
Authors: Rubel Kolin E. , Lubner Rory J. , Lopez Andrea A. , Li Ping , Huang Li‐Ching , Sheng Quanhu , Wu Jeffanie , Wise Sarah K. , DelGaudio John M. , Chandra Rakesh K. , Chowdhury Naweed , Turner Justin H.
Published: June 2023

Background

Central compartment atopic disease (CCAD) is an emerging phenotype of chronic rhinosinusitis with nasal polyposis (CRSwNP) characterized by prominent central nasal inflammatory changes. This study compares the inflammatory characteristics of CCAD relative to other phenotypes of CRSwNP.

Methods

A cross‐sectional analysis of data from a prospective clinical study was performed on patients with CRSwNP who were undergoing endoscopic sinus surgery (ESS). Patients with CCAD, aspirin‐exacerbated respiratory disease (AERD), allergic fungal rhinosinusitis (AFRS), and non‐typed CRSwNP (CRSwNP NOS) were included and mucus cytokine levels and demographic data were analyzed for each group. Chi‐squared/Mann‐Whitney U tests and partial least squares discriminant analysis (PLS‐DA) were performed for comparison and classification.

Results

A total of 253 patients were analyzed (CRSwNP, n = 137; AFRS, n = 50; AERD, n = 42; CCAD, n = 24). Patients with CCAD were the least likely to have comorbid asthma (p = 0.0004). The incidence of allergic rhinitis in CCAD patients did not vary significantly compared to patients with AFRS and AERD, but was higher compared to patients with CRSwNP NOS (p = 0.04). On univariate analysis, CCAD was characterized by less inflammatory burden, with reduced levels of interleukin 6 (IL‐6), IL‐8, interferon gamma (IFN‐γ), and eotaxin relative to other groups and significantly lower type 2 cytokines (IL‐5, IL‐13) relative to both AERD and AFRS. These findings were supported by multivariate PLS‐DA, which clustered CCAD patients into a relatively homogenous low‐inflammatory cytokine profile.

Conclusions

CCAD has unique endotypic features compared to other patients with CRSwNP. The lower inflammatory burden may be reflective of a less severe variant of CRSwNP.
Biophysical study on DNA and BSA binding activity of Cu(II) complex: Synthesis, molecular docking, cytotoxic activity, and theoretical approach
Authors: Tarai Swarup Kumar , Mandal Saikat , Tarai Arup , Som Ipsita , Pan Angana , Bagchi Arka , Biswas Arunima , Moi Sankar Ch.
Published: June 2023

The bidentate (N, O) donor Schiff base, methyl‐4‐(2‐hydroxybenzylidene‐amino) benzoate (HL), was synthesized for the synthesis of CuL2 complex. Their structures were characterized by single crystal X‐ray diffraction and spectroscopic methods. The important structural features of ligand HL are (space group: Pca21; a = 6.1434(7) Å; b = 7.1021(7) Å; c = 28.963(3) Å; α = 90.00°; β = 90.00°, and γ = 90.00°) and of CuL2 are (space group: P21/n; a = 15.763(7) Å; b = 8.1921(5) Å, and c = 20.1955(8) Å; α = 90.00°; β = 96.547(4)°, and γ = 90.00°). The DFT/TD‐DFT studies were performed to evaluate the structure optimization, MEP plot, and electronic spectroscopy data as well as the HOMO‐LUMO energy and also other electronic descriptor properties. The DNA and BSA binding property of both the ligand and complex were studied employing a variety of spectroscopic methods, viscosity experiments, and gel electrophoresis technique. Their biophysical study including 3D fluorescence, FRET calculation, and anisotropy measurements with BSA were studied by spectrofluorometric methods. The molecular docking simulation of the ligand HL and CuL2 was executed with DNA and BSA to observe their different weak and strong binding interactions and to compare their binding aptitude with biomolecules and experimental results. The software “PASS” for drug likeness prediction and “ADMET” for bioactivity were implemented to get an idea about the antineoplastic and bioactivity aspects of HL and CuL2 complex. The anticancer property of the Cu(II) complex was measured by MTT assay against human breast carcinomas (MCF‐7) cancer cell line and as well as normal human embryonic kidney cells (HEK293) and is less toxic and comparable anticancer activity compared to cisplatin and oxaliplatin. The annexin V‐FITC, propidium iodide assay by flow cytometric method, and reactive oxygen species (ROS) production assay by DCFDA were assessed in presence of the HL and CuL2 for their cell death mechanism proceed via either apoptosis or necrosis.
Mechanochemical Rhodium‐Catalyzed C−H Bond Amidation of Ferrocenes by Ball Milling
Authors: Li Hao , Ma Tongtong , Wang Yingxin , Wang Bosen , Li Dianjun , Yang Jinhui
Published: June 2023

A direct protocol for Rh‐catalyzed C−H amidation of ferrocenes in a ball mill using dioxazolones as the amide source under solvent‐free conditions was developed. The corresponding ortho‐aminated products were formed in 3 hours and the yields were up to 99% in the absence of base. This method could be a typically sustainable and environmental‐friendly alternative method to traditional methodologies, with the advantages of wide substrate range, good functional group tolerance and gram‐scale synthesis.