bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning from (In)Constant Infrastructures
Authors: Trujillo-Torres Sebastián
Published: January 2024

As part of a larger research endeavour, this article operates in the context of current conditions and potentialities of street vending in India, as a city-making constant. It begins by examining frequent, yet, questionable tropes utilised to justify their exclusion from urban planning and design narratives as a main issue to debate: tropes that are then debunked and disproven, after methodically mapping and unpacking the design and infrastructural features of selected case studies. Street vending is therefore explored as a distinct type of infrastructural system in itself, one which is simultaneously a constant factor, and an inconstant array of procedures and processes. It possesses distinct temporal and spatial features seemingly incompatible with conventional planning and design understandings. This article is therefore intended to attempt not only to legitimize the spatial-systemic practices of these infrastructures as a developmental asset, but to outline clues for designers to reimagine urban futures that can lead to more equitable city-making practices.
Addressing Cultural Stigma: Endometriosis Diagnosis in the Arab World
Authors: Al Shukri Maryam , Easa Abdulla Mohammed Almarzooqi Maryam
Published: January 2024

Endometriosis, a challenging chronic disease, has often been shrouded in delayed diagnosis. Efforts to enhance the quality of life for affected women by facilitating earlier diagnoses is crucial. Early diagnosis in the teenage years can impact not only the individual but also her family. In conservative cultures such as those found in the Arab world, including the Arab Peninsula, North Africa, and East Asia, reproductive capacity stands as a defining feature in a woman’s life. Endometriosis, viewed as both a stigma and a threat to reproductive capabilities, can significantly influence a girl’s marriage prospects, especially as within these cultural contexts, marriage is perceived as a protective shield, guarding against potential future hardships. The stigma associated with endometriosis intensifies the anxieties of both the affected girl and her parents about the future. This policy commentary dives into the intricacies of reproductive stigma, offering thoughtful suggestions to systematically address it on both policy and societal levels. The proposed interventions involve active engagement with adolescent girls, their families, partners, schools, healthcare institutions, specialized professionals, workplaces, and the broader communities. Comprehensively addressing these aspects can foster a supportive environment that empowers individuals to navigate the challenges posed by endometriosis in conservative cultures.
Beyond Contraception: The Medical Necessity of Hormonal Contraceptives for Optimal Health and Well-being of Women in the UAE
Authors: Al Awar Shamsa , Zaręba Kornelia
Published: January 2024

Introducing contraception as a method of treatment of many diseases is essential in order to optimize health and well-being of women in the UAE. The aim of the presented study was to analyze the non-contraceptive benefits and possible methods of using hormonal contraception in cultural context of the country. We reviewed articles concerning non-contraceptive use of contraception. Authors conducted their search in Pubmed/Medline, Scopus, Web of Science, EMBASE, CINAHL, National Library of Medicine, and Google Scholar. Hormonal contraceptives offer several health and wellness benefits that can improve the overall quality of life for women. These benefits encompass mood stabilization, reduction of premenstrual symptoms, acne relief, recurrent functional ovarian cysts, and luteal hemorrhagic cysts prevention, positive impact on bone mineral density, treatment of abnormal uterine bleeding, menstrual cycle abnormalities dysmenorrhea, ovarian and endometrial cancer prevention. It can also be used as a symptomatic method of treatment of PCOS and endometriosis. Moreover, it can guarantee appropriate birth spacing and can be prescribed for women with certain medical conditions where pregnancy poses significant risks to their health. Expanding access to hormonal contraceptives for non-contraceptive medical purposes requires a multi-faceted approach, including policy changes, regulatory reforms, insurance coverage adjustments, and educational initiatives for healthcare providers and the general public
Analysis The Competitiveness of Indonesian Tobacco Exports to International Markets 2003-2022
Authors: Nur Salsabila Nadhifah , Tarik Ibrahim Jabal , Mumpuni Ningsih Gumoyo
Published: January 2024

Indonesia as an open economy country establishes trade relations with other countries in the world to sell excess and buy shortages of products needed by a country. International trade has two important activities, there are exports and imports. Both of these are the main activities that play a major role in a countrys economy. One way that a country can increase and improve its economic conditions is by increasing competitiveness through comparative and competitive advantage. One of the commodities from Indonesia that is demand in international market is tobacco. Tobacco is product from the leaves of Nicotiana genus that can be used as pesticides, medicines, and cigarettes. Therefore, this research aims to determine competitiveness of Indonesian tobacco exports comparatively and competitively through RCA and TSI analysis. This study also aims to find out whether Indonesian tobacco can win the market or not through AR analysis. The results obtained are the average value of RCA 2.12 indicates that Indonesian tobacco has a comparative advantage. The average value of TSI 0.21 indicates that Indonesian tobacco has a strong competitive advantage, tends to be an exporter country and Indonesia in export expansion period. The average value of AR 1.57 indicates that Indonesia is able to capture the tobacco market and Indonesias position is getting stronger in the export and domestic market. It can be concluded that Indonesian tobacco has comparative and competitive advantage and Indonesian tobacco is able to capture the tobacco market to international market.
Miasta zbyt małe na handel z dyskontem
Authors: Wilk Waldemar
Published: January 2024

Jednym z najdynamiczniej rozwijających się formatów handlu są współcześnie sklepy dyskontowe, wykorzystujące w procesie zdobywania rynku strategię niskich cen. Na skutek szybkiego rozwoju o charakterze organicznym oraz fuzji i przejęć na obecnym etapie rozwoju rynku mamy do czynienia z istnieniem kilku sieci sklepów dyskontowych o zasięgu ogólnokrajowym. Placówki te rozmieszczone są w wielu miastach Polski, jednak dosyć nierównomiernie. Wychodząc od analizy wielkości i zasięgu przestrzennego sieci sklepów dyskontowych w Polsce, autor podejmuje się analizy rozwoju tego sektora usług w małych miastach poprzez ukazanie dynamiki tego zjawiska, wskazania czynników lokalizacji oraz porównania pod względem położenia i struktury społeczno-gospodarczej małych miast ze sklepami dyskontowymi i tych bez dyskontów.
Kierunki rozwoju wybranych małych miast dolnośląskich w okresie 1995-2008
Authors: Chądzyńska Elżbieta
Published: January 2024

Małe miasta położone w otoczeniu metropolii znajdują się w szczególnej sytuacji. Z jednej strony mogą korzystać z rozwijającego się w pobliżu dużego rynku pracy, jednocześnie rozwijający się rynek dużego miasta stanowi zagrożenie dla rozwoju lokalnych rynków pracy. Pomiędzy miastem centralnym a otoczeniem, dzięki procesom suburbanizacji, odbywają się migracje ludności. Charakterystyczną cechą ruchów migracyjnych w ostatnich latach jest przenoszenie się mieszkańców dużych miast na tereny przyległe. Celem artykułu jest analiza zmian przestrzenno-funkcjonalnych i gospodarczych w małych miastach leżących w strefie oddziaływania Wrocławskiego Obszaru Metropolitalnego. Wzięty pod uwagę okres czasu (1995‒2008) pozwolił na określenie skutków zaistniałych przemian i ich wpływu na dalszy rozwój.
Regularities of zero charge formation on the surface of clay particles exposed to pressure
Authors: Seredin Valeriy V. , Sheina Ksenia V. , Siteva Olga S.
Published: January 2024

Relevance. Caused by the need to study the effect of high pressure on the change in pH value of the point of zero charge of clay minerals. The point of zero charge is one of the most important characteristics of a diluent. The magnitude of the charge is largely controlled by the pH values of a pore solution. As it is known, clays of different genesis have excellent physical and chemical properties, which directly affects the value of the zero charge point. Aim. To identify the patterns of formation of the zero charge point of clay particles exposed to pressure. Objects. Kaolin clay of the Nizhne-Uvelsky deposit of the Chelyabinsk region and bentonite clay of the Zyryanovsky deposit of the Kurgan region. Methods. potentiometric titration, determination of the point of zero charge was carried out using the construction of potentiometric titration curves. Microsoft Excel, SigmaPlot, Statistica software was used. Results. When processing clays by pressure, there is a decrease in the content of aluminum ions (Al3+) in the packages of kaolinite and montmorillonite, the transition of Al3+ ions into the diffuse layer of the clay particle, where aluminum ions bind hydroxyl ions, while the released hydrogen ions increase the acidity of the suspension. Activation by pressure of kaolin and bentonite clays has a multidirectional effect on the change in the ion-exchange capacity of clays and, as a result, on the pH of the point of zero charge on the surface of clay particles. The authors developed statistical models that allow predicting the pH of the zero charge point from clay activation pressure data. Knowledge of the characteristics of the charge on the surface of clay particles makes it possible to explain the mechanism of sorption and other processes.
Study of the composition of high molecular asphaltenes of bituminous oils using ruthenium ion-catalyzed oxidation reaction
Authors: Cheshkova Tatiana V. , Ostapenko Darya V. , Kovalenko Elena Yu. , Sagachenko Татyana А. , Min Raisa S.
Published: January 2024

Relevance. Conditioned by the need to expand the amount of data on composition and structure of the asphaltene constituents of heavy oils. The data are important for creation of new and modernization of existing technologies for processing unconventional hydrocarbon raw materials. Aim. To study the composition of structural fragments in macromolecules of asphaltenes of bituminous oils from the Ashalchinskoe, Usinskoe, and Nurlatskoe oilfields using the ruthenium ion-catalyzed oxidation. Object. Fractions of high-molecular asphaltenes, which make up the bulk of the asphaltene constituents of the Ashalchinskoe, Usinskoe, and Nurlatskoe oils (94.1; 92.1 and 95.0 rel. %). Methods. Elemental analysis, cryoscopy in benzene, selective chemical destruction of Car–C bonds using a ruthenium ion-catalyzed oxidation, gas chromatography–mass spectrometry. Results. It has been established that the structure of high-molecular asphaltenes of bituminous oils from the Ashalchinskoe, Usinskoe, and Nurlatskoe oilfields contains fragments bound to the core of their molecules through Car.–C bridges and compounds trapped in the hollow cells of macromolecular entities of asphaltenes during kerogen cracking. It follows from the analysis of the oxidation products that the covalently bonded fragments are represented by C8–C32 n-alkanes, branched C9–C30 alkanes (2-methylalkanes and C15, C19, C20 isoprenoids), C22–C24 cheilanthanes, C27, C29–C33 hopanes and long chain alkyl bridges (C9–C30) connecting aromatic blocks. Most of the fragments linked by Car.–C bridges are linear paraffin chains. Typical biological markers, i. e. n-alkanes and hopanes were identified among the occluded compounds.
Waste management in potash mining companies
Authors: Perevoshchikova Anna A. , Perevoshchikov Roman D. , Malyshkina Elizaveta E. , Mitrakova Natalya V.
Published: January 2024

Relevance. Related to the need to carry out environmental protection measures in potash mining areas exposed to the environmental consequences of the impact of multi-tonnage salt waste. Aim. To summarise and analyse the geography of potash mining operations, the environmental impact of these operations, and potash waste management practices. Object. Potash mining waste. Methods. Theoretical and logical analysis of the data. Results. The research considers the geographical distribution of potash deposits and presents the characteristics of potash mining waste using the example of the Verkhnekamskoe Potash Deposit. The paper provides both domestic and foreign analyses of ecological consequences of waste storage on the day surface. Several options for potash mining waste management are analysed. For the management of clay-salt slurry, the most effective approach is its injection into underground horizons, which includes the use of saturated solutions as a fertiliser component, as a part of a product in construction, and in the oil industry. A more comprehensive approach to halite waste management is needed. Waste disposal to waste dumps is relevant due to the presence of mined-out areas on the territory of long-operating enterprises. Reclamation of the salt dump will help to isolate it from atmospheric precipitation, thereby reducing the inflow of saturated water into the environment. Utilising waste for production of construction materials is the most economically and environmentally favourable option. Extracting valuable components, producing fertilisers, concentrates, etc. from waste is the least practical approach due to the ecological and economic expenses involved in acquiring extraction equipment and the repeated generation of waste. The most challenging aspect of reducing waste generation in terms of technology lies in improving mining operations and implementing selective mining.
A EMERGÊNCIA DOS ESTADOS GERAIS E AS ORIGENS LUSO-AMERICANAS DE SEU EXPANSIONISMO ULTRAMARINO (1580-1609)
Authors: SILVA JOÃO GABRIEL COVOLAN
Published: January 2024

Neste artigo buscamos relacionar a formação dos Estados Gerais após a revolta contra o poderio espanhol, caracterizando alguns aspectos centrais do novo Estado, e a intensificação de sua presença mercantil em territórios e possessões ultramarinas das potências ibéricas. Acreditamos que já no período final do século XVI e na primeira década do século XVII, o Estado neerlandês, com forte presença da classe comercial em sua administração, já se delineia uma política expansionista, a qual tem o Brasil e o comércio de açúcar como um objetivo central. A interação crescentemente assimétrica entre redes comerciais portuguesas e neerlandesas desvela-se como aspecto marcante da configuração da potência ascendente na disputa colonial europeia.
FORGING CONNECTIONS ACROSS REMOTENESS: Colonization Projects and Global Dynamics in Amazonia and the Guianas (Late 1800s - Early 1900s)
Authors: BASÍLIO ROMÁRIO SAMPAIO
Published: January 2024

This paper analyzes colonization projects and schemes that aimed to connect two remote regions in South America: the northern Brazilian Amazonia and the British colony of Guyana, during the transition from the late nineteenth century to the early twentieth century. The central problem is to understand projects designed to break or reduce remoteness and create cross-border connections (infrastructure, social and commercial linkages) that would cross societies and markets in different crisis scenarios, and to question the extent to which the ‘decadence’ denounced by contemporaries was a conjunctural element within long-term structural dependencies that cannot be solely attributed to competitiveness, mechanization limitations, or production rationalization. This study adopts a diachronic historical approach to examine three key aspects: (1) the challenges posed by the prolonged dominance of sugar monoculture in British Guyana and the concurrent rubber boom in the Brazilian Amazonia; (2) the interrelated matters of circulation and labor scarcity; and (3) the persistent issue of food shortages amid the setbacks encountered by integration endeavors.
NOS RASTROS DE INÁCIA VAZ: venturas e desventuras de uma pesquisa
Authors: FARIA REGINA HELENA MARTINS DE
Published: January 2024

O artigo compartilha a motivação, o desenvolvimento e os resultados da pesquisa para desvendar um enigma: quem foi e quando viveu a mulher que dá nome ao município de Buriti de Inácia Vaz - MA. A falta de comprovação documental sobre a origem dela tem levado à criação de versões que a veem como branca, negra escravizada ou indígena. O foco direcionou-se para um indício aparentemente irrefutável: uma família de Caxias - MA considera-se descendente dela. Foram utilizados documentos eclesiásticos, cartoriais e a imprensa da época, para apresentar a situação socioeconômica dessa Inácia e de seu marido, além da atuação política do seu pai e do sogro. Essa é a maior contribuição da pesquisa porque não encontrei qualquer ligação dela e seus familiares com Buriti e, por um acaso, chegou-me uma informação que afasta inteiramente a possibilidade dessa Inácia ser a que deu nome ao Buriti. Seguirei outros indícios.
Apontamentos de Reflexões Inconclusas, por Enrique Padrós: BOLSONARO E A CULTURA DO ÓDIO
Authors: PADRÓS (In memorian) ENRIQUE
Published: January 2024

Este texto inédito foi o último artigo escrito por Padrós. Embora apresente algumas lacunas e ideias a desenvolver, optamos por publicá-lo resguardando sua originalidade como forma de homenagem ao autor. Além das reflexões temos uma pequena mostra do processo criativo de um autor/pesquisador maduro, como estrutura seus diálogos antes de oferecer uma versão final a seus leitores. Mesmo nas lacunas há ensinamentos.
O HOSPITAL DE CARIDADE E O CONTEXTO DAS EPIDEMIAS EM SÃO LUÍS NA SEGUNDA METADE DO SÉCULO XIX
Authors: COE AGOSTINHO JÚNIOR HOLANDA
Published: January 2024

Desde os primórdios da sua existência em Portugal, no século XV, uma das grandes características desenvolvidas pelas Misericórdias foi a administração de hospitais nos lugares em que essas instituições foram edificadas. Em São Luís, a Irmandade desde cedo buscou centralizar as ações no campo da assistência médica. Em 1805, possuindo igreja e cemitério, já encontramos relatos sobre a existência de um hospital de caridade administrado pela Misericórdia. Na economia da Misericórdia, os hospitais significaram quase sempre um grande peso nas contas da instituição, as reclamações que versavam sobre a dificuldade de manutenção dos hospitais eram recorrentes e se acirravam em momentos de epidemias. Talvez, nessa obra esteja o principal ponto de discordância entre os irmãos congregados e as administrações locais. Os irmãos quase sempre acreditavam que necessitavam de mais recursos para o cuidado dos doentes, sobretudo, durante as crises epidêmicas, enquanto que os administradores locais alegavam que os já existentes eram suficientes para dar prosseguimento à administração dos hospitais.
Comparing internal versus external fixation for diaphyseal tibial and fibular fractures in skeletally immature dogs
Authors: Chitty Jake , Aldridge Paul
Published: January 2024

PICO Question
In skeletally immature dogs with simple non-displaced diaphyseal tibial and fibular fractures does internal fixation compared with external fixation result in less postoperative complications and improved fracture healing?
 
Clinical bottom line
Category of research
Treatment.
Number and type of study designs reviewed
There were no publications that answered the PICO question.
Strength of evidence
None.
Outcomes reported
Both external skeletal fixation and internal fixation are reported as techniques for diaphyseal tibial and fibular fracture management in companion animals, though no study has been reported to compare these techniques directly, or to report fracture healing and postoperative complications in skeletally immature dogs with non-displaced diaphyseal tibial fractures.
Conclusion
Given the absence of evidence answering the PICO, choice and recommendation on treatment for non-displaced diaphyseal tibial and fibular fractures in skeletally immature dogs should be decided on personal experience and stabilisation methods available to the veterinarian such as external fixation or internal fixation. Both surgical techniques have been reported in skeletally mature and immature dogs with diaphyseal tibial fractures, but not specifically in skeletally immature patients with non-displaced diaphyseal tibial and fibular fractures. They are both applicable methods of fixation for tibial fractures in companion animals, though there is lacking evidence for which has more favourable outcomes for non-displaced diaphyseal tibial and fibular fractures in skeletally immature dogs as no studies have directly compared these stabilisation techniques.
 
How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Comunicación educativa en pospandemia
Authors: Crovi Druetta Delia
Published: January 2024

Las prácticas actuales de la comunicación educativa se caracterizan por emplear mediaciones digitales, tanto en clases presenciales como en programas a distancia. Las constantes innovaciones tecnológicas interpelan los procesos y contenidos educomunicativos, por lo que es necesario renovar su análisis a partir de una perspectiva multidisciplinaria. El presente artículo lleva adelante una discusión documental crítica que parte del caso mexicano y busca identificar y conocer estos procesos, enfocándose en los ejes del cambio que la digitalización impone a la comunicación educativa actual. En tal sentido, la educación del presente, pospandémica, tiene características singulares: es digital, ubicua y transmediática, además de estar condicionada por una nueva dimensión espacio-temporal y la disponibilidad de un volumen ilimitado de información.

En estas circunstancias, crear y evaluar conocimientos legitimados y verosímiles presenta una serie de desafíos que abarca las dinámicas tanto comunicativas como pedagógicas, las brechas de habilidades y la conectividad tecnológicas, como así también la revisión de las políticas públicas sobre la problemática. Sólo a partir de la identificación de estos retos y un abordaje analitico que escuche la voz de los protagonistas educativos (maestros, estudiantes e instituciones) será posible alimentar políticas que actúen en consecuencia, así como proponer novedosas estrategias metodológicas para la enseñanza, la investigación y la difusión del conocimiento científico.
Development of Contextual Learning-Based E-Module in Elementary School
Authors: Juwantara Ridho Agung , Harjanto Ambyah , Sutiyono Akhmad , Utari Dwi
Published: January 2024

This research was motivated by the unavailability of contextual learning-based E-Modules in Civic lessson for Class IV Student of Insan Mandiri Elementary School at Bandar Lampung, so teaching and learning activities in class are still lacking in variety. E-Module are important for students to use because they make learning easier. A contextual approach is used to help student learn by associating learning material with the life around. The research method of this study used Development Research with the ADDIE model. Questionnaires, interviews, tests as data collection tools. This research is analyzed and explained with numbers and descriptive. Based on the results of the research, the material validation results were 83%, language validation was 93%, and design validation was 91%. The results of the teacher's response test were 78% and the student's response test was 80% in the "Decent" category. The effectiveness test obtained an average of 91 in the "Very High" effectiveness category. This research shows that the development of Civics E-Module teaching products based on contextual learning is urgently needed and deserves to be disseminated.
1923-1980 Yılları Arasında Kadınlar Tarafından Çıkarılan Dergiler
Authors: YILDIRIM Taner , ÇELİK Yakup
Published: January 2024

29 Ekim 1923 tarihinde cumhuriyetin ilan edilmesiyle birlikte gelişen toplumsal eşitlik fikri ve toplumun farklı katmanları arasındaki bütünleşme düşünceleri ve bu doğrultuda yapılan çalışmalar neticesinde Türk kadını da her alanda kendini göstermiştir. Bundan dolayı bilimden sanata, ekonomiden sanayiye, eğitimden kültürel faaliyetlere, spordan ziraata kadar geniş bir sahada Türk kadınının izi görülmeye başlanmıştır. Yayımlandığı döneme ayna tutan dergiler, cumhuriyetten sonra kadınların nazariyesi ile çıkmış ve olayların kadın gözüyle görülmesini sağlamıştır. Makalemizin konusunu 29 Ekim 1923 tarihinden sonra cumhuriyetin kadınları tarafından çıkarılmış olan dergiler oluşturmaktadır. 1923-1980 yılları arasına temas edilecek olan bu çalışmada Adımlar, Fikirler, Yeni Yayınlar, Tarla, Şiir Sanatı ve Türk Çocukları ele alınacak olan dergilerdir. Farklı sahalar hakkında yayımlanmış olan bu dergilerde kadınların pek çok konuya hâkim oldukları tespit edilmeye çalışılacaktır. Ele alınan yayınların değişik görüşleri barındırmasına ve çeşitli türleri ihtiva etmesine özen gösterilecek ve bu sayede cumhuriyetin kazanımları neticesinde kadınların her konuda ve her görüşte dergi çıkarabildiği açıklanmaya çalışılacaktır.
Artificial Intelligence: A Kalam and Sufi Perspective
Authors: Khalili A.
Published: January 2024

The recent remarkable progress in Artificial Intelligence (AI) has renewed the discussion on the possibility of human-level AI. Despite the difficulty of the problem and the presence of many large gaps and challenges, most people working in the field think that human-level AI is achievable, but they disagree on the date. In this paper, I briefly discuss the possibility of human-level AI from the perspective of two traditions in the Islamic world, namely Kalam and Sufism, and despite their different mode of investigation, they converge to the same conclusion on this topic.
Impact of Various Non-contrast Enhanced MRA Techniques on Lumen Visibility in Vascular Flow Models with Surpass Evolve Flow Diverter
Authors: Ozpeynirci Yigit , Gorodezky Margarita , Sanches Augusto Fava , Solana Ana Beatriz , Liebig Thomas
Published: January 2024

Background: Silent MRA has shown promising results in evaluating the stents used for intracranial aneurysm treatment. A deep learning-based algorithm was recently introduced by GE. The purpose of this study was to compare the performance of several MRA techniques in lumen visibility in silicone models with flow diverter stents.
Methods: Two Surpass Evolve stents of different sizes were implanted in two silicone tubes. The tubes were placed in separate boxes in straight position and in two different curve configurations and connected to a pulsatile pump to construct a flow loop. Using a GE 3.0T scanner, TOF and silent MRA images were acquired, and deep learning reconstruction was applied to the silent MRA dataset. Intra-luminal signal intensity in the stent (SIin-stent), in the tube outside the stent (SIvessel) and of the background (SIbg) were measured for each scan.
Results: The SIin-stent/SIbg and SIin-stent/SIv ratio were higher on silent scans and DL-based reconstructions than on TOF images. The stent tips created severe artefacts on TOF images, which could not be observed on silent scans.
Conclusions: Our study demonstrated that the DL algorithm improved the quality of the silent technique in evaluating the flow diverter stent patency.
An Exploratory Bio-Informatic Investigation of Cats’ Susceptibility to Coronavirus-Deriving Epitopes
Authors: Buonocore Michela , De Biase Davide , Sorrentino Domenico , Giordano Antonio , Paciello Orlando , D’Ursi Anna Maria
Published: January 2024

Coronaviruses are highly transmissible and pathogenic viruses for humans and animals. The vast quantity of information collected about SARS-CoV-2 during the pandemic helped to unveil details on the mechanisms behind the infection, which are still largely elusive. Recent research demonstrated that different class I/II human leukocyte antigen (HLA) alleles might define an individual susceptibility to SARS-CoV-2 spreading, contributing to the differences in the distribution of the infection through different populations; additional studies suggested that the homolog of the HLA in cats, the Feline Leukocyte Antigen (FLA), plays a pivotal role in the transmission of viruses. With these premises, this study aimed to exploit a bioinformatic approach for the prediction of the transmissibility potential of two distinct Feline Coronaviruses (FCoVs) in domestic cats (Feline enteric Coronavirus, FeCV and Feline Infectious Peritonitis Virus, FIPV) using SARS-CoV-2 as the reference model.

We performed an epitope mapping of nonapeptides deriving from SARS-CoV-2, FeCV and FIPV glycoproteins and predicted their affinities for different alleles included in the three main loci in class I FLAs (E, H and K). The predicted complexes with the most promising affinities were then subjected to molecular docking and molecular dynamics simulations to provide insights into the stability and binding energies in the cleft. Results showed the FLA proteins encoded by alleles in FLA-I H (H*00501 and H*00401) and E (E*01001 and E*07001) loci are largely responsive to several epitopes deriving from replicase and spike proteins of the analyzed coronaviruses. The analysis of the most affine epitope sequences resulting from the prediction can stimulate the development of anti-FCoV immunomodulatory strategies based on peptide drugs.
Orbital stabilization of dynamically elongated small satellite using active magnetic attitude control
Authors: Monakhova Uliana Vladimirovna
Published: January 2024

The paper proposes an algorithm for angular motion control of a dynamically elongated spacecraft. The algorithm is based on the direct Lyapunov method using matrix control coefficients. The calculated mechanical torque is implemented using a magnetic attitude control system. Control parameters are selected using Floquet theory to ensure convergence of the motion trajectory to the required one. A numerical study of controlled motion to achieve gravitational attitude equilibrium of a 3U CubeSat is carried out.
Exploring of the Factors Behind Disaster-Related Deaths
Authors: Inagaki Marina ,   Editorial Office
Published: January 2024

This study was conducted to elaborate on the factors contributing to indirect deaths due to earthquakes between 1995 and 2016 in Japan and to identify their prevalence by focusing on life and health changes. A content analysis was conducted to determine the factors using documents provided by the local government. From the 472 indirect death cases, 12 categories and 137 detailed factors were identified. From the 13 cases related to suicide, six categories and 15 detailed factors were extracted. Among the categories, intense disaster-related work was ranked highest, followed by damage to jobs and property and family changes. For the other 459 non-suicide related causes of death, 12 categories and 122 detailed factors were extracted. The most prevalent categories were related to delay or interruption of treatment due to hospital shutdowns, followed by changes in living conditions. In detailed factor of living conditions, cold or hot environments—which are due to being washed away by tsunamis, weather, drafty shelters, the number of evacuees, damaged infrastructure, and a lack of clothes—were found in 60 cases. In conclusion, maintenance of medical services, promotion of a safe environment, and identification and intervention of high-risk people based on these factors are imperative. Developing assessment tools based on these factors for future research is essential to estimate the size of high-risk populations, assist in the distribution of limited resources, and respond quickly to survivors in disasters.
Examining the Relationship Between Disaster Scenarios and Disaster Management Behavior During Earthquakes
Authors: Nakazawa Kosuke ,   Editorial Office, Ohtomo Shoji , Kimura Reo , Nagata Toshimitsu , Ikeda Masaki
Published: January 2024

This study examines the effect of the recognition of various disaster scenarios on the disaster management behavior of people. It analyzes the data (n = 1,900) of the social surveys, conducted by the National Research Institute for Earth Science and Disaster Resilience (NIED) in seven districts of Japan (Hokkaido/Tohoku, Kanto, Chubu, Kinki, Chugoku, Shikoku, and Kyushu). The study indicates that the experience of victims, recognition of earthquake occurrence in the region and of earthquake hazard maps, as well as the factors, “life threatening,” “difficulties in daily life,” and “induced disasters,” in the disaster scenarios are related to their disaster management behavior. The greater their recognition of “life threatening” and “difficulties in daily life,” the more people will adopt disaster management behaviors. This study suggests that, added to the experience of victims and the recognition of the occurrence of earthquakes and of hazard maps, the image of the damage through specific disaster scenarios affects people’s disaster management behavior. On the other hand, it has become apparent that creating images of “induced disasters” that are caused by earthquakes, with their unclear association, may lead to psychological confusion.
Sistema emprendedor basado en redes de conocimiento para la sustentabilidad empresarial: hacia una aproximación teórico-conceptual
Authors: Canales García Rosa Azalea , Montiel Méndez Oscar Javier
Published: January 2024

El objetivo de este trabajo consiste en examinar explícitamente la relación entre sustentabilidad empresarial, redes de conocimiento y emprendimiento como un conjunto holístico de conexiones de naturaleza compleja. Para ello, se propone un marco teórico-conceptual denominado “Sistema emprendedor basado en redes de conocimiento para la sustentabilidad empresarial”. La justificación reside en la inexistencia un esbozo orientado a identificar los aspectos que intervienen en la conducta emprendedora desde los puntos de vista reticular, cognitivo y sustentable. La construcción de la propuesta se lleva a cabo mediante una investigación de carácter exploratorio y documental. Los resultados apuntan la factibilidad del planteamiento ya que es posible relacionar teóricamente la sustentabilidad y las redes de conocimiento mediante la figura del emprendedor.
Positive Airway Pressure Therapy Compliance in Patients With Comorbid Insomnia and Sleep Apnea
Authors: Bae Mi Rye , Lee Young-Ha , Lee Sei Won , Chung Seokhoon , Chung Yoo-Sam
Published: January 2024

Objectives. This study aimed to compare positive airway pressure (PAP) therapy compliance between patients with comorbid insomnia and sleep apnea (COMISA) and those with obstructive sleep apnea (OSA) alone. It also assessed the influence of insomnia clinic visits on PAP compliance.Methods. Patients diagnosed with OSA and initiated on PAP therapy between January 2012 and December 2021 were included. The COMISA group (n=43) comprised patients with insomnia, while the control group (n=86) consisted of OSA patients without insomnia, matched 1:2 based on age and sex. COMISA patients were further categorized into group A (n=20), with at least two insomnia clinic visits, and group B (n=23) with one or no visits. PAP compliance in each group was evaluated at 3 and 9 months.Results. No significant differences were observed in PAP compliance between the COMISA patients and OSA patients without insomnia. Within the COMISA group, the impact of insomnia clinic visits on PAP compliance was not significant. No significant difference was observed in daily PAP usage between the two groups at 3 months (265.5±145.9 minutes in group A vs. 236.3±152.3 minutes in group B, P=0.760) or 9 months (213.4±155.3 minutes in group A vs. 166.3±158.3 minutes in group B, P=0.538). The percentages of PAP users and nights with PAP use exceeding 4 hours also showed no significant differences at either time point.Conclusion. This study demonstrated no significant disparity in PAP compliance between the COMISA and OSA groups at either 3 or 9 months. Furthermore, insomnia clinic visits did not significantly impact PAP compliance in COMISA patients during 3- and 9-month intervals.
El deseo trans en 20.000 especies de abejas
Authors: García Catalán Shaila
Published: January 2024

In 20,000 species of bees by Estibaliz Urresola (2023) a girl goes through a painful journey: from Aitor to Coco and from Coco to Lucía she tries to define with her own name the enigma she feels in the face of her strangeness: she feels that she has been born in a wrong body On this painful journey, his mother, Ane, will try to accompany him gropingly, disoriented, while he seeks to define his own desire through working with sculpture. In this text we analyze the film by Estibaliz Urresola as a key film of “another new Spanish cinema signed by women” that attends to trans desire by working on film forms in a self-conscious way, demanding listening to the particular through haptics, sorority and work with misunderstanding. We are interested in the stylems, the expressive and narrative elements in the staging, the putting in images and the editing as well as their intertexts with queer cinema or cinema directed by women of their generation. We will conclude that Lucía is the emblem of that transcendence and secret that every family must respect in the heirs.
El cuerpo político, la contrasexualidad, la dildotectónica y los nuevos placeres en Las hijas del Fuego (2018) de Albertina Carri
Authors: Perdomo Rodríguez Karina
Published: January 2024

This research addresses the analysis of the cinematographic treatment that film director Albertina Carri makes, in the feature film Las hijas del fuego (2018), of female sexual enjoyment and pleasure, making a different use of sexual devices, such as the dildo, dispensing with the symbology and the reference focused on what is exclusively masculine as normative in reference to sexual enjoyment and the identification that it implies of identity. The Argentine director tries to overcome what was maintained by the feminist film theorist Laura Mulvey (1975) regarding the scopophilic gaze of men and the traditional sexual conception of women in conventional cinema and in pornographic cinema, in particular.
Applying queer theory on the dissidence of bodies and genders, specifically that developed by Paul B. Preciado on dildo technology and contrasexuality, the research focuses on Carri's cinematographic discourse on the techniques and technologies of enjoyment and pleasure sexual.
In conclusion Carri manages to show what Preciado elaborates in his Contrasexual Manifesto (2011) and that he continues to develop in other books such as Testo Yonki (2020), etc., in which he maintains that counter-conducts and counter-devices must be created, reappropriating those who have normalized bodies giving them a different use to create new techniques that facilitate new pleasures.
Integrated Asset Modelling and Field Development of a Gas Condensate Field
Authors: Farooq U. , Ashraf Z. , Yousaf H. , Ahmad S. , Saqib C. M. , Ali M.
Published: January 2024

Optimized production from gas reservoirs comes with many challenges, especially in a case where there are several fields present around the main target reservoir, sharing common surface facilities. This study is aimed at integrated asset modelling of a gas field with over 1 Tscf of gas initially in place. The objective is to couple a layered reservoir, wells with comingled production and surface facilities, and to recognize the full potential as well as bottlenecks for creating a development plan for prolonging the field life.

The field consists of a main central reservoir, which is surrounded by compartmentalized satellite regions with production potential. The study begins with geophysical interpretation, followed by petrophysical and static modelling. The static model is used to initialize the dynamic model and a simulated realization of the main central reservoir is created. The satellite fields are modelled using material balance modelling. The reservoirs are then coupled together with the surface facilities network using the vertical lift profiles of all wells. Forecasts are run along with economic modelling to propose an optimized development scheme considering workovers, infill wells as well as surface compression. The main challenge is to create an optimized history matched integrated network model incorporating all available data, compared to a standalone simulation model with no consideration of surface constraints. Another challenge is to create coupled subsurface realization using both simulation model for central reservoir and tank models of more than 10 satellite compartments.

The goal of the study is meeting the sales requirements for as long as possible and maximizing the return on investment. Based on the integrated model, workovers and infill wells have been proposed that increase the plateau production period. Wells with underestimated flow potential are realized and choke optimization has been proposed for prolonging the plateau before bringing surface compression online. The water production constraints of the fields have been incorporated and realized in the modelling process. The surface compression has been proposed in three stages over the life cycle of the field, along with the timeline and location of compressors, to produce the fields until wellhead pressures approach atmospheric.

The unique aspect of this study is the ability to model complex multilayered reservoirs systems with multiple compartments and combine them with the well and surface models to create a comprehensive and robust tool for reservoir management and decision making. A tool that can be updated down the road with minimum effort, to keep up with the field behavior. Such integrated asset models serve as testing grounds to see expected outcomes and gain a level of confidence before any development strategy can be applied.
Improvement in Drilling Efficiency by Using Mechanical Thruster in BHA and Long Gauge Bit - A Case Study
Authors: Moiz Humaid , Sarfaraz Zaman , Khan Shahjahan , Sabir Usama Bin , Ali Abid , Shahid Azeem , Hussain Saadat , Asim Muhammad , Uddin Waqas
Published: January 2024

Drilling interbedded formations which contains stingers of siltstone and sand can be a tough challenge. This paper provides an insight into the combination of Long Gauge PDC bits and Mechanical Thruster in the BHA which can address the drilling efficiency in interbedded lithologies mentioned above. Aggressive bits can provide better drill-ability in interbedded lithologies but carries a high risk of cutter damage and the Mechanical Thruster reduces the high to severe vibration levels that are generated while using aggressive bits and keeps the bit engaged at bottom. The standard Matrix body PDC bit is used to drill formations with interbedded lithologies consisting of stingers of siltstone and sandstone in massive clay formation. Historically, whenever an aggressive PDC bit design is used, high stick and slip and vibrations have been limiting factors in increasing weight on bit (WOB) and, consequently, the rate of penetration (ROP).

On a recent Well, the vibrations severely limited the ROP by up to 35% and the team realized that a more aggressive bit design is needed to improve ROP. To mitigate the projected high vibrations, a longer gauge PDC bit with a metal body and a 19mm cutter was utilized which has better stability and reduced tendency for vibrations. Secondly, a Mechanical Thruster was introduced into the bottom hole assembly (BHA) which balances out the pressure drop below tool with the WOB and hence de-couple the drill string below the tool from the rest of the BHA.

This balance of hydraulic force with the WOB, smooths out the downhole WOB variation, minimizing bit induced vibration and improving the on-bottom ROP. In the 12-1/4″ section, ROP dropped at 3000m as the siltstone percentage increased. WOB was increased to 60+klbs with limited success. The matrix body 6-bladed bits were pulled green and hence it was decided to run 5-bladed 19mm steel body bits with 6″ undercut gauge. To minimize the vibrations and stick-slip with 5-bladed 19mm bit, Mechanical Thruster was run in the BHA for the first time. During all the three subsequent runs with Mechanical Thruster and long gauge bit, operator was able to increase ROP by 35+%, reduce vibration to a similar level as that of earlier bit while using aggressive bits. The Mechanical Thruster provided consistent WOB, with aggressive parameters while building confidence in the usage of steel body bit design in silty claystone formations.
Full-Endoscopic Extraforaminal Approach for Extraforaminal Herniated Intervertebral Disc Disease: Exploring Challenging Case
Authors: Lee Jae Hwan , Chang Kai-Sheng , Sun Li-Wei , Chen Kuo-Tai , Chen Chien-Min
Published: January 2024

Extraforaminal lumbar disk herniation (E-LDH) constitutes a challenging subset of lumbar disk herniations. Minimally invasive methods like full-endoscopic lumbar discectomy provide benefits but carry risks of complications, such as postoperative dysesthesia and nerve root injury. A 62-year-old male with comorbidities presented with severe leg pain due to left L3/4 E-LDH. An L3 nerve block, guided by fluoroscopy, was performed with the patient in a right decubitus position. After alleviating the pain, the patient was placed in a prone position to undergo the extraforaminal full-endoscopic procedure under local anesthesia. The tip of the needle was targeted to the base of the superior articular process (SAP). Foraminoplasty was precisely performed with a high-speed diamond burr at the base of the SAP, facilitating the removal of the extraforaminal portion of the herniated disc. The procedure yielded immediate relief (visual analogue scale score reduced from 10 to 0). There was no leg pain or associated back pain at the 6-month follow-up. This approach demonstrates the feasibility of an extraforaminal full-endoscopic technique for E-LDH, overcoming challenges associated with the uncooperative patient due to the severe leg pain. However, the technique demands technical proficiency and warrants further research to establish its broader applicability.