bluuebunny/crossref_metadata_2025 huggingface dataset:
Parcelamento de fósforo em algodoeiro irrigado
Authors: Aquino Leonardo Angelo de , Berger Paulo Geraldo , Neves Júlio César Lima , Lima Tricia Costa , Aquino Rosiane Filomena Batista Almeida de
Published: April 2012

A maioria das regiões de cultivo de algodoeiro no Brasil apresenta baixa fertilidade dos solos, especialmente com relação ao fósforo (P) disponível. Objetivou-se avaliar a aplicação parcelada de doses de P em algodoeiro irrigado, visando a uma maior eficiência da adubação fosfatada, em comparação com a aplicação tradicional, em semeadura. O experimento foi desenvolvido em Neossolo Quartzarênico com 22 mg dm-3 de P (disponibilidade média), no norte de Minas Gerais. Utilizou-se delineamento em blocos ao acaso, em arranjo fatorial (4x3) + 3, com três repetições. Os fatores estudados foram doses de P2O5 (0 kg ha-1, 30 kg ha-1, 60 kg ha-1, 120 kg ha-1 e 180 kg ha-1) e três formas de aplicação parcelada (80% e 20%; 60% e 40%; 40% e 60% da dose do fertilizante aplicada em semeadura e aos 35 dias após a emergência (DAE), respectivamente), além da aplicação de 0 kg ha-1, 60 kg ha-1 e 120 kg ha-1 de P2O5 na semeadura. A fonte de P foi o superfosfato triplo granulado e houve aumento no conteúdo de P, na parte aérea, em função das doses aplicadas. Os teores de nutrientes na folha índice, exceto P, não foram influenciados pelas doses de P e pelos parcelamentos. O teor de P na folha índice e o número de capulhos por planta aumentaram com o incremento das doses de P, mas não foram influenciados pelo parcelamento do fertilizante fosfatado. A aplicação de 40% da dose de P em semeadura e do restante parcelado aos 35 DAE reduziu a produtividade de algodão em caroço, não havendo efeito significativo nos demais parcelamentos.
Milho pipoca consorciado com feijão em diferentes arranjos de plantas
Authors: Viegas Neto Antonio Luiz , Heinz Rafael , Gonçalves Manoel Carlos , Correia Allan Michel Pereira , Mota Leandro Henrique de Souza , Araújo Willian Dias
Published: April 2012

O cultivo de milho pipoca em consórcio com feijão é uma alternativa para o pequeno produtor, por proporcionar maior retorno econômico e aproveitamento da área de cultivo, além de diminuir os riscos de perda. Neste trabalho, avaliaram-se diferentes sistemas de consórcio de milho pipoca com feijão. O experimento foi realizado em campo experimental da Universidade Federal da Grande Dourados, em Dourados (MS). Utilizou-se delineamento experimental de blocos ao acaso, com quatro repetições, e tratamentos em esquema de parcelas subdivididas, no qual as parcelas constituíram-se de duas cultivares de milho pipoca (Zélia e BRS Ângela) e as subparcelas de três sistemas de consórcio de milho pipoca com feijão BRS MG Pioneiro (milho + feijão na linha do milho, milho + feijão na entrelinha do milho e milho + feijão na linha do milho + feijão na entrelinha do milho) e milho pipoca em monocultivo. Os sistemas de consórcio avaliados não afetaram a produtividade do milho pipoca e a semeadura do feijão na linha + entrelinha do milho resultou em maior produtividade da leguminosa. De maneira geral, o consórcio das duas espécies reduziu os rendimentos do feijoeiro, entretanto, devido aos valores do Índice de Equivalência de Área, foi 50% a 91% mais eficiente que os monocultivos.
"Batizando e ressignificando práticas pedagógicas" no ensino da língua materna: o papel da formação continuada
Authors: Eitelven Adriane Angheben , Fronza Cátia de Azevedo
Published: April 2012

Neste trabalho, reflete-se sobre questionamentos de professores que participaram de um programa de formação continuada ocorrido no Rio Grande do Sul, oferecido pelo Ministério da Educação, em parceria com a Secretaria Municipal de Educação. Parte-se das impressões que os educadores tinham no início da referida formação, comparando-as às compreensões explicitadas ao final do curso. Neste período de formação, compartilhando experiências e conhecimento, aliando teoria e prática, dúvidas e inquietações foram dando espaço a novas perspectivas para reavaliar e modificar o fazer pedagógico. Destaca-se que o letramento, assumido em todo o processo de ensino e de aprendizagem, é, acima de tudo, ensinar o aluno a falar, ver, ouvir, ler, escrever, calcular, entre tantas outras habilidades. Todavia, primeiro, os professores precisam aprender a fazê-lo.
Quality of Life and Its Associated Factors in Patients with Hepatocellular Carcinoma Receiving One Course of Transarterial Chemoembolization Treatment: A Longitudinal Study
Authors: Shun Shiow-Ching , Chen Chien-Hung , Sheu Jin-Chuan , Liang Ja-Der , Yang Jyh-Chin , Lai Yeur-Hur
Published: April 2012

Learning Objectives:

After completing this course, the reader will be able to: List the top 10 ranked symptoms after discharge suffered by patients with hepatocellular carcinoma (HCC) receiving transarterial chemoembolization (TACE) treatment.Identify the significant factors in the associations between quality of life (QOL) and demographic factors and clinical factors over a period of 2 months in patients with HCC receiving TACE.Design individualized education programs for newly diagnosed and recurrent HCC patients in order to maintain better QOL after treatment.

CME This article is available for continuing medical education credit at CME.TheOncologist.com

Objective.

To (a) explore changes in physical and psychological distress and quality of life (QOL) and (b) identify the significant pre- and postdischarge factors related to changes in physical and mental domains of QOL over a period of 2 months in patients with hepatocellular carcinoma receiving one course of transarterial chemoembolization (TACE) treatment.

Methods.

A longitudinal prospective design was used, with participants recruited from a teaching hospital in Northern Taiwan. Data were collected three times: within 3 days prior to discharge (T0) and at the fourth (T1) and eighth (T2) weeks after discharge. A set of structured questionnaires was used to assess participants' QOL, symptom distress, anxiety, and depression. Changes in QOL and associated factors were examined using generalized estimating equations.

Results.

Eighty-nine patients were included in this study. Fatigue was reported to be the most distressful symptom after treatment. Overall QOL improved monthly after discharge. Change in physical QOL 2 months after TACE treatment was associated with age, diagnosis status, level of symptom distress, and depression after discharge. Change in mental QOL was significantly associated with gender, diagnosis status, and anxiety and depression after discharge.

Conclusions.

Health care providers should pay special attention to patients of older age, those who are male, and those who have higher levels of depression and anxiety after discharge. Designing personalized education programs before discharge for patients with newly diagnosed cancer versus those who have recurrent disease is suggested to help patients maintain a better QOL after discharge.
Letter to the Editor Regarding “A Prospective, Controlled Study of the Botanical Compound Mixture LCS101 for Chemotherapy-Induced Hematological Complications in Breast Cancer” by Yaal-Hahoshen et al. (
The Oncologist
2011;16:1197–1202)
Authors: Mooiman Kim D. , Goey Andrew K.L. , Meijerman Irma , Beijnen Jos H. , Schellens Jan H.M.
Published: April 2012

A prospective, randomized, placebo-controlled study by Yaal-Hahoshen et al. published in a recent issue of The Oncologist that concluded that the botanical mixture LCS101 prevented hematological complications in breast cancer patients undergoing anthracycline- and taxane-based chemotherapy is critically reviewed.
Gainsborough flood defence scheme: improving project delivery by reusing existing assets
Authors: Ford Ken , Dineley Malcolm , Zilles Andreas
Published: April 2012

This paper shows how an integrated team enabled the UK Environment Agency to deliver a more cost-effective and sustainable solution to improving protection for over 2600 properties in Gainsborough, Lincolnshire, from flooding by the tidal River Trent. The team identified several opportunities to cut costs, mitigate risks and reduce carbon dioxide emissions. At the outset, a detailed condition assessment and numerical analysis of existing flood defence structures enabled many of them to be reused, even though most were originally thought to be at the end of their design life. This and other initiatives resulted in cost savings £10 million, a shorter construction period and significantly lower environmental impact.
Achieving more for less at Canary Wharf Crossrail station, London
Authors: Yeow Hoe , Nicholson Duncan , Bryant Cliff , Westbury Martin
Published: April 2012

Innovative thinking and willingness to break with the norm were two of the main ingredients to successful delivery of the first Crossrail station at Canary Wharf in London. For example, minimising the environmental impact of construction activities in an urban environment led to the use of an innovative silent piling technique, which in turn led to significant cost savings and cut a year off the programme. In addition, a flexible approach to design development allowed continuous improvements in layout to be made to generate further cost and programme savings, with additional savings arising during construction through adoption of the observational method.
Contribution of nitrous oxide emissions from wastewater treatment to carbon accounting
Authors: Winter P. , Pearce P. , Colquhoun K.
Published: April 2012

This paper describes research that investigated the contribution of nitrous oxide (N2O) emissions from wastewater treatment to the greenhouse gas emissions of a wastewater treatment plant (WWTP). The research provided several months of robust data from a large-scale WWTP serving a population equivalent of 284,000. N2O emissions were monitored online at the ventilation system of a covered activated sludge (AS) plant, therefore capturing the complete off-gas stream. This methodology eliminated errors incurred through sampling of small percentages of emission areas and allowed representative continuous measurements. Nitrogen load and dissolved oxygen (DO) were also monitored. To address seasonal variation, data were recorded in two extensive phases. In addition, three separate 24-hour surveys were conducted. Emissions of CO2, CH4 and N2O associated with treatment were calculated using the UK Water Industry Research carbon accounting workbook. This study measured N2O emissions from the AS process (nitrification and denitrification) equivalent to 17.5% of the annual GHG emissions (tonnes CO2e) from processes at the WWTP. The emissions were within the range of published N2O emissions. The diurnal profiles confirmed literature findings of a trend of increased N2O emissions when the DO decreased. The DO in the high rate zone of the aeration lanes should be kept above 1 mg l−1 to avoid favourable conditions for N2O emissions during nitrification.
Oral Mucocele of Unusual Size on the Buccal Mucosa: Clinical Presentation and Surgical Approach
Authors: Seo Juliana , Bruno Ingrid , Artico Gabriela , Vechio Aluana dal , Migliari Dante A
Published: April 2012

Oral mucoceles are small-size, benign minor salivary gland pathologies. The most frequent localizations of these lesions are the lower lip mucosa. However, in some cases, they grow to an unusual size and hinder the preliminary diagnosis of mucocele. The purpose of this article is to report a case of a large oral mucocele with a diameter of 3.5 cm on the buccal mucosa of a 43-years-old male patient. The surgical procedure was carried out for a complete removal of the lesion.
Positive solutions of differential equations with unbounded Green’s kernel
Authors: Graef John , Padhi Seshadev , Pati Smita , Kar P.K.
Published: April 2012

Sufficient conditions are obtained for the existence/nonexistence of at least
two positive periodic solutions of a class of first order differential
equations having an unbounded Green?s function. An application to an
ecological model with strong Allee effects is also given.
Fetal ultrasound scan: Prerogatives for the basic level
Authors: Novakov-Mikic Aleksandra , Ilic Djordje , Vejnovic Tihomir , Kopitovic Vesna , Kapamadzija Aleksandra , Sekulic Slobodan
Published: April 2012

Adequate level of prenatal ultrasound scan is a prerequisite for a successful
definition of high risk population that needs further investigations.
?Basic?, standardized fetal mid-trimester scan, with an informative report
enables not only diagnosis of anomaly but also evaluation of state of
pregnancy in general. This paper was aimed at reviewing the benefits of and
requirements for a complete basic mid-trimester fetal ultrasound scan and the
necessary documentation. Potential directions for development of organization
of basic mid-trimester fetal ultrasound scans are standardization of the
scan, with establishing the number and the level of examination, and
continual education of both the doctors and the patients. In order to
standardize the exam, a uniform check list is needed, so that the examination
should always be done in the same manner and at the same level, no matter
where it is done and by whom. International and national guidelines should be
agreed upon and they should state clear standards on who should do the scan,
how, what kind of ultrasound machine should be used and what documentation
should be kept. This paper presents a possible standardization of basic level
mid trimester fetal ultrasound scan. A routine complete second trimester
ultrasound between 18 and 22 weeks and a complete ultrasound report will
provide the best opportunity to diagnose fetal anomalies and to help in the
management of prenatal care. It will also reduce the unnecessary number of
ultrasound examinations done during the second trimester for completion of
fetal anatomy survey, which would decrease the costs.
The role and importance of biochemical markers in diagnosis of alcoholic acute pancreatitis
Authors: Tesic-Rajkovic Snezana , Radovanovic-Dinic Biljana , Jevtovic-Stoimenov Tatjana
Published: April 2012

Introduction. Alcoholic acute pancreatitis occurs in 10% of alcoholics, who
take more than 80g alcohol daily. Different biochemical markers are used to
diagnose acute pancreatitis, and some of them may help in establishing
etiology of acute pancreatitis. Material and Methods. This study is a
prospective review of 21 patients. All patients were hospitalized at the
Department for Gastroenterology and Hepatology or at the Department for
Surgery of the Clinical Centre of Nis in the period from August 1st 2009 to
March 1st 2010 with diagnosis of acute alcoholic pancreatitis. Detailed
anamnesis, clinical examination, biochemical analyses and ultrasonography of
the upper abdomen were done in all patients. All patients provided data on
alcohol abuse. Results. The analysis of the corresponding biochemical
parameters revealed a statistically significant correlation between the
following values: serum amylase and serum lipase (R=0.964674; p<0.001),
cholesterol and triglycerides (R=0.93789; p<0.001), total and direct
bilirubin (R=0.857899; p<0.001) and between aspartate aminotransferase and
alanine aminotransferase (R=0.824461, p<0.001) in patients with alcoholic
acute pancreatitis. In addition, there was a statistically significant
correlation between the values of serum amylase and urinary amylase
(R=0.582742, p<0.001). Discussion. The analysis of biochemical markers showed
that some of them were significant for beforehand diagnosis of alcoholic
acute pancreatitis, which is in accordance with other studies. Conclusion
Some biochemical parameters can be potential predictors of alcoholic acute
pancreatitis (lipase/amylase ratio >2, greater ratio of aspartate
aminotransferase/ alanine aminotransferase, enhanced triglycerides and values
of mean corpuscular volume.
Dispersed settlement in detached houses: Attitudes over the residential space consumption in Slovenia
Authors: Hocevar Marjan
Published: April 2012

Public opinion surveys investigating the levels of environmental awareness
target the most diverse aspects of environment pollution, but they rarely
examine people's attitudes to the ways and forms in which space itself is
used or consumed, especially in the context of residential or settlement
patterns. This article analyses the connection between the prevailing
long-term value orientations about residential preferences in Slovenia, which
we associate with an ideology of ?anti-urbanism?, and the resulting
?schizophrenic? environmental perception, which expresses itself as
relatively high declared environmental awareness of people who do not live in
a town. Extensive and dispersed use of the physical space (defined as a
sprawl) is in general one of the issues of environmental degradation.
Dispersion and low settlement density, as well as the connected consumption
of physical space in detached houses, is even more rarely addressed as the
key issue of the environment problem. The absence of comprehensive
?ecologisation? of the ways in which space is consumed for residential
purposes in Slovenia is of a structural nature. Its structural captivity is
identified on ideological, institutional, planning, and individual levels.
Dispersed individualised settlement is critically addressed, but usually seen
from the angle of pollution and not as an immanent ecological problem, i.e.
the consumption of space as a rare commodity. In surveys on spatial values,
we come across the phenomenon that parochial ruralism is equated with
environmentalism, something we explain with a schizophrenic environmental
perception, when respondents consider living in individual family houses
environmentally more acceptable than living in multi-dwelling houses in an
urban environment.
Configurational forces and shape of a sessile droplet on a rotating solid substrate
Authors: Lubarda Vlado , Talke Kurt
Published: April 2012

The shape of a uniformly rotating liquid droplet deposited on a solid
substrate is determined by an iterative numerical integration of the
governing nonlinear differential equation. The differential equation and the
boundary conditions are derived by means of the variational analysis which
delivers the expressions for the specific configurational force per unit area
of the liquid/vapor interface, and the configurational force along the
liquid/solid/vapor contact circle. An analytical proof for the orthogonality
of the specific configurational force to the surface of the droplet is
constructed. The effect of rotation on the droplet?s gyrostatic shape is
discussed.
Serum Apolipoproteins Are Associated With Systemic and Retinal Microvascular Function in People With Diabetes
Authors: Sasongko Muhammad Bayu , Wong Tien Y. , Nguyen Thanh T. , Kawasaki Ryo , Jenkins Alicia J. , Shaw Jonathan , Robinson Carol , Wang Jie Jin
Published: April 2012

Serum apolipoprotein (apo)AI and -B have been shown to be associated with diabetic retinopathy, but the underlying mechanisms are unclear. We investigated whether apoAI and apoB levels are associated with measures of systemic and retinal microvascular function in patients with diabetes. We recruited 224 diabetic patients (85 type 1 and 139 type 2) and assessed serum lipids and lipoproteins from fasting blood, skin responses to sodium nitroprusside (endothelium independent) and acetylcholine (ACh) (endothelium dependent) iontophoresis, flicker-light–induced retinal vasodilatation, and retinal vascular tortuosity. After adjustment for age and sex, every SD increase in apoAI level was associated with ACh-induced skin perfusion (mean change 1.27%; P < 0.001 for apoAI) and flicker-light retinal arteriolar vasodilatation (0.33%; P = 0.003) and was associated inversely with arteriolar tortuosity (−2.83 × 10−5; P = 0.044). Each SD increase in apoB was associated with arteriolar tortuosity only (1.75 × 10−5; P = 0.050). These associations, except for apoB, remained in multivariate models. Serum apoAI was associated with increased vasomotor responsiveness to ACh and flickering light and inversely related to retinal vessel tortuosity—a characteristic that has both structural and functional dimensions. These findings provide additional insights into the potential mechanisms of apos in the pathogenesis of diabetic retinopathy and other diabetic microvascular complications.
High Concentrations of AGE-LDL and Oxidized LDL in Circulating Immune Complexes Are Associated With Progression of Retinopathy in Type 1 Diabetes
Authors: Lopes-Virella Maria F. , Baker Nathaniel L. , Hunt Kelly J. , Lyons Timothy J. , Jenkins Alicia J. , Virella Gabriel ,   the DCCT/EDIC Study Group
Published: April 2012

OBJECTIVE

To determine whether immunocomplexes (ICs) containing advanced glycation end product (AGE)–LDL (AGE-LDL) and oxidized LDL (oxLDL) contribute to the development of retinopathy over a 16-year period in subjects with type 1 diabetes.

RESEARCH DESIGN AND METHODS

Levels of AGE-LDL and oxLDL in ICs were measured in 517 patients of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort. Retinopathy was assessed by stereoscopic fundus photography. Cox proportional hazards models were used to assess the effect of AGE-LDL-ICs and oxLDL-ICs on retinopathy progression.

RESULTS

In unadjusted models, higher baseline levels of AGE-LDL-ICs and oxLDL-ICs significantly predicted progression of diabetic retinopathy outcomes. After adjustment by study-design variables (treatment group, retinopathy cohort, duration of type 1 diabetes, and baseline albumin excretion rate [AER], hemoglobin A1c (HbA1c), and Early Treatment Diabetic Retinopathy Study [ETDRS] score), one SD increase in IC levels was associated with 47% (hazard ratio [HR] 1.47 [95% CI 1.19–1.81]; AGE-LDL-IC) and 45% (1.45 [1.17–1.80]; oxLDL-IC) increased risk of developing proliferative diabetic retinopathy (PDR) and 37% (1.37 [1.12–1.66]; to both ICs) increased risk of progressing to severe nonproliferative retinopathy. Analyses were stratified by retinopathy cohort because results differed between primary and secondary cohorts. For AGE-LDL-ICs, HR for progression to PDR was 2.38 (95% CI 1.30–4.34) in the primary cohort and attenuated in the secondary cohort (1.29 [1.03–1.62]). Similar results were observed for oxLDL-ICs.

CONCLUSIONS

Increased levels of AGE-LDL and oxLDL in ICs are associated with increased risk for progression to advanced retinopathy in patients with type 1 diabetes, indicating that the antibody response to modified LDL plays a significant role in retinopathy progression.
Interactions of Ipomoea aquatica and Utricularia reflexa with phytoplankton densities in a small water body in northern Nigeria
Authors: Chia Mathias , Adelanwa Michael , Ladan Zakari , Iortsuun Dora , Adanyi Sewuese , Stephen Bala
Published: April 2012

The interactions of Ipomoea aquatica and Utricularia reflexa with phytoplankton densities were studied in a small water body in Zaria, Nigeria from June to November 2007. The negative effects of both macrophytes on 10 out of 15 phytoplankton taxa, including Staurastrum sp., Netrium sp., Ulothrix sp., Marssionella sp. and Closterium sp. were differentiated from other environmental effects. U. reflexa, on the other hand, showed positive associations with species like Actinocyclus sp., Palmellopsis sp., Spirotaenia sp., Microcystis sp. and Marssionella sp. Qualitative phytochemical screening and FT-IR analyses confirmed the presence of glycosides, anthraquinone, saponins, steroids, triterpenes, flavonoids, and alkaloids in Ipomoea aquatica and Utricularia reflexa. The observed variations in phytoplankton community dynamics were closely related to the presence of these macrophytes as well as the environmental conditions in the pond.
Vertical micro-distribution of psammonic ciliates and their relationship to physical and chemical parameters in two lakes of different trophic status
Authors: Mieczan Tomasz , Nawrot Dorota
Published: April 2012

The aim of this study was to examine the community structure and vertical micro-distribution of psammonic ciliates in two lakes of different trophic status in eastern Poland. Additionally, the size and trophic structure of these microorganisms, and the influence of physical and chemical water parameters on their abundance, were analysed. Psammon samples were collected during spring, summer, and autumn of 2010. In each of the lakes samples were collected in the euarenal, higroarenal, and hydroarenal zones of the psammolittoral. In order to determine the micro-vertical distribution of ciliates, each sample was divided into two sub-samples: the upper part (0–1cm) and the lower part (1–2cm). The species diversity of ciliates decreased with depth. The tendency was particularly clear in mesotrophic lakes. Irrespective of the lake’s trophic type and arenal zones, significantly higher numbers and biomass of ciliates were recorded in the surface layer of the psammolittoral. The upper layer of sand was dominated by omnivorous taxa, whereas the deeper layer showed increases in the proportions of bacterivore species. The factors limiting the occurrence of ciliates are mainly concentrations of total organic carbon and nutrients.
Sulfur in the marine environment
Authors: Jasińska Anita , Burska Dorota , Bolałek Jerzy
Published: April 2012

Sulfur is an element commonly occurring in the environment. It is present in the atmosphere, in the hydrosphere, and in live organisms; it is one of the most important physicochemical and geological indicators. Depending on the natural conditions, sulfur compounds in the environment may play the role of electron acceptor or donor in the redox processes. These compounds influence the ion concentration and ion balance in benthic sediments. They also determine the speciation, bioavailability and toxicity of heavy metals. Comprehensive knowledge of the processes mediated by sulfur can be a valuable source of information about the past and present state of the ecosystem.
Estimation of the Interference in Multi-Gas Measurements Using Infrared Photoacoustic Analyzers
Authors: Zhao Yongjing , Pan Yuee , Rutherford Jerry , Mitloehner Frank M.
Published: April 2012

Two methods were described to estimate interference in the measurements of infrared (IR) photoacoustic multi-gas analyzer (PAMGA). One is IR spectroscopic analysis (IRSA) and the other is mathematical simulation. An Innova 1412 analyzer (AirTech Instruments, Ballerup, Denmark) with two different filter configurations was used to provide examples that demonstrate the two methods. The filter configuration in Example #1 consists of methane (CH4), methanol (MeOH), ethanol (EtOH), nitrous oxide (N2O), carbon dioxide (CO2), and water vapor (H2O), and in Example #2 of ammonia (NH3), MeOH, EtOH, N2O, CO2, and H2O. The interferences of NH3 as a non-target gas in Example #1 were measured to validate the two methods. The interferences of H2O and NH3 as target gases in Example #2 were also measured to evaluate the analyzer’s internal cross compensation algorithm. Both simulation and experimental results showed that the interference between the target gases could be eliminated by the internal cross compensation algorithm. But the interferences of non-target gases on target gases could not be addressed by the internal cross compensation, while they could be assessed by the IRSA and mathematical simulation methods. If the IR spectrum of a non-target gas overlaps with that of target gas A at filter A, it could affect not only gas A (primary interference), but also other target gases by secondary interference (because the IR spectrum of gas A overlaps with gas B at filter B and thus affects gas B measurements). The IRSA and mathematical simulation methods can be used to estimate the interference in IR PAMGA measurements prior to purchase or calibration of the unit.
Immune Response to Sipuleucel-T in Prostate Cancer
Authors: Thara Eddie , Dorff Tanya B. , Averia-Suboc Monica , Luther Michael , Reed Mary E. , Pinski Jacek K. , Quinn David I.
Published: April 2012

Historically, chemotherapy has remained the most commonly utilized therapy in patients with metastatic cancers. In prostate cancer, chemotherapy has been reserved for patients whose metastatic disease becomes resistant to first line castration or androgen deprivation. While chemotherapy palliates, decreases serum prostate specific antigen and improves survival, it is associated with significant side effects and is only suitable for approximately 60% of patients with castrate-resistant prostate cancer. On that basis, exploration of other therapeutic options such as active secondary hormone therapy, bone targeted treatments and immunotherapy are important. Until recently, immunotherapy has had no role in the treatment of solid malignancies aside from renal cancer and melanoma. The FDA-approved autologous cellular immunotherapy sipuleucel-T has demonstrated efficacy in improving overall survival in patients with metastatic castrate-resistant prostate cancer in randomized clinical trials. The proposed mechanism of action is reliant on activating the patients’ own antigen presenting cells (APCs) to prostatic acid phosphatase (PAP) fused with granulocyte-macrophage colony stimulating factor (GM-CSF) and subsequent triggered T-cell response to PAP on the surface of prostate cancer cells in the patients body. Despite significant prolongation of survival in Phase III trials, the challenge to health care providers remains the dissociation between objective changes in serum PSA or on imaging studies after sipleucel-T and survival benefit. On that basis there is an unmet need for markers of outcome and a quest to identify immunologic or clinical surrogates to fill this role. This review focuses on the impact of sipuleucel-T on the immune system, the T and B cells, and their responses to relevant antigens and prostate cancer. Other therapeutic modalities such as chemotherapy, corticosteroids and GM-CSF and host factors can also affect immune response. The optimal timing for immunotherapy, patient selection and best sequencing with other prostate cancer therapies remain to be determined. A better understanding of immune response may help address these issues.
Equivalence of Electron-Vibration Interaction and Charge-Induced Force Variations: A New O(1) Approach to an Old Problem
Authors: Powell Benjamin J. , Baruah Tunna , Pederson Mark R.
Published: April 2012

Calculating electron-vibration (vibronic) interaction constants is computationally expensive. For molecules containing N nuclei it involves solving the Schrödinger equation for Ο(3N) nuclear configurations in addition to the cost of determining the vibrational modes. We show that quantum vibronic interactions are proportional to the classical atomic forces induced when the total charge of the system is varied. This enables the calculation of vibronic interaction constants from O(1) solutions of the Schrödinger equation. We demonstrate that the O(1) approach produces numerically accurate results by calculating the vibronic interaction constants for several molecules. We investigate the role of molecular vibrations in the Mott transition in κ-(BEDT-TTF)2Cu[N(CN)2]Br.
Computing the Topological Entropy of Multimodal Maps via Min-Max Sequences
Authors: Amigó José María , Dilão Rui , Giménez Ángel
Published: April 2012

We derive an algorithm to recursively determine the lap number (minimal number of monotonicity segments) of the iterates of twice differentiable l-modal map, enabling to numerically calculate the topological entropy of these maps. The algorithm is obtained by the min-max sequences—symbolic sequences that encode qualitative information about all the local extrema of iterated maps.
Self-Energy Closure for Inhomogeneous Turbulent Flows and Subgrid Modeling
Authors: Frederiksen Jorgen S.
Published: April 2012

A new statistical dynamical closure theory for general inhomogeneous turbulent flows and subgrid modeling is presented. This Self-Energy (SE) closure represents all eddy interactions through nonlinear dissipation or forcing ‘self-energy’ terms in the mean-field, covariance and response function equations. This makes the renormalization of the bare dissipation and forcing, and the subgrid modeling problem, transparent. The SE closure generalizes the quasi-diagonal direct interaction closure to allow for more complex interactions. The SE closure is applicable to flows in different geometries, is exact near maximum entropy states corresponding to canonical equilibrium, and provides a framework for deriving simpler realizable closures.
Risk-Association of CYP11A1 Polymorphisms and Breast Cancer Among Han Chinese Women in Southern China
Authors: Sun Minying , Yang Xuexi , Ye Changsheng , Xu Weiwen , Yao Guangyu , Chen Jun , Li Ming
Published: April 2012

Exposure to endogenous sex hormones has been reported as a risk factor for breast cancer. The CYP11A1 gene encodes the key enzyme that catalyzes the initial and rate-limiting step in steroid hormone synthesis. In this study, the associations between single nucleotide polymorphisms (SNPs) in CYP11A1 and breast cancer susceptibility were examined. Six SNPs in CYP11A1 were genotyped using the MassARRAY IPLEX platform in 530 breast cancer patients and 546 healthy controls. Association analyses based on a χ2 test and binary logistic regression were performed to determine the odds ratio (OR) and 95% confidence interval (95% CI) for each SNP. Two loci (rs2959008 and rs2279357) showed evidence of associations with breast cancer risk. The variant genotype C/T-C/C of rs2959008 was significantly associated with a decreased risk (age-adjusted OR, 0.75; 95% CI, 0.58–0.96; P = 0.023) compared with the wild-type TT. However, the homozygous TT variant of rs2279357 exhibited increased susceptibility to breast cancer (age-adjusted OR, 1.44; 95% CI, 1.05–1.98; P = 0.022). The locus rs2959003 also showed an appreciable effect, but no associations were observed for three other SNPs. Our results suggest that polymorphisms of CYP11A1 are related to breast cancer susceptibility in Han Chinese women of South China.
Increasing the Detection Limit of the Parkinson Disorder through a Specific Surface Chemistry Applied onto Inner Surface of the Titration Well
Authors: Mille Caroline , Debarnot Dominique , Zorzi Willy , El Moualij Benaïssa , Coudreuse Arnaud , Legeay Gilbert , Quadrio Isabelle , Perret-Liaudet Armand , Poncin-Epaillard Fabienne
Published: April 2012

The main objective of this paper was to illustrate the enhancement of the sensitivity of ELISA titration for neurodegenerative proteins by reducing nonspecific adsorptions that could lead to false positives. This goal was obtained thanks to the association of plasma and wet chemistries applied to the inner surface of the titration well. The polypropylene surface was plasma-activated and then, dip-coated with different amphiphilic molecules. These molecules have more or less long hydrocarbon chains and may be charged. The modified surfaces were characterized in terms of hydrophilic—phobic character, surface chemical groups and topography. Finally, the coated wells were tested during the ELISA titration of the specific antibody capture of the α-synuclein protein. The highest sensitivity is obtained with polar (Θ = 35°), negatively charged and smooth inner surface.
Dynamic Sensing of Localized Corrosion at the Metal/Solution Interface
Authors: Li Wei , Yuan Boyu , Wang Chao , Li Liang , Chen Shenhao
Published: April 2012

A Mach-Zehnder interferometer is employed to detect localized corrosion at the metal/solution interface in the potentiodynamic sweep of the iron electrode in solutions. During the electrochemical reactions, local variations of the electrolyte’s refractive index, which correlate with the concentration of dissolved species, change the optical path length (OPL) of the object beam when the beam passes through the electrolyte. The distribution of the OPL difference was obtained to present the concentration change of the metal ions visually, which enable direct evidence of corrosion processes. The OPL difference distribution shows localized and general corrosion during the anodic dissolution of the iron electrode in solutions with and without chloride ions, respectively. This method provides an approach for dynamic detection of localized corrosion at the metal/solution interface.
2-Allylphenyl glycosides as complementary building blocks for oligosaccharide and glycoconjugate synthesis
Authors: Premathilake Hemali D , Demchenko Alexei V
Published: April 2012

The O-allylphenyl (AP) anomeric moiety was investigated as a new leaving group that can be activated for chemical glycosylation under a variety of conditions, through both direct and remote pathways. Differentiation between the two activation pathways was achieved in a mechanistic study. The orthogonal-type activation of the AP moiety along with common thioglycosides allows for the execution of efficient oligosaccharide assembly.
Work-Related Injuries Among Certified Nursing Assistants Working in US Nursing Homes
Authors: Khatutsky Galina , Wiener Joshua , Anderson Wayne , Porell F.W.
Published: April 2012

Certified nursing assistants (CNAs) working in nursing homes are at significant risk for work-related injuries, but little is known about the frequency and types of their injuries, and how assistive equipment such as patient lifts affects injury rates. The study described in this research report analyzed the prevalence, nature, and predictors of injuries among CNAs working in US nursing homes. Researchers used 2004 data from the National Nursing Assistant Survey and the National Nursing Home Survey. One of their findings was that 60 percent of all CNAs nationally reported a work-related injury in the year prior to the survey.
Ni avec toi, ni sans toi
Authors: Santona Alessandra , Zavattini Giulio-Cesare
Published: April 2012

Résumé L’amour est en partie imputable à des objets internes qui représentent les fantasmes de la relation dont les individus sont porteurs et qu’ils tentent de réactualiser dans le lien de couple. Lorsque la capacité d’explorer les états mentaux – les siens propres et ceux de l’autre – échoue (accordage affectif, Stern, 1985), il s’ensuit : a ) un dommage à la capacité de réfléchir sur les expériences mentales et de différencier les émotions (« identification projective excessive ») ; b ) la négation de l’indépendance de l’objet ainsi que de la dépendance de la relation, associée à une énorme anxiété à l’idée d’un « triangle conjugal de couple » (Ruszczynski, 1997). Dans le cas clinique relaté de M. et M me D, le thérapeute a tenté de différencier, dans la première intervention, les thèmes individuels (pour M me D : le refus inconscient du rôle de la mère masochiste et soumise associé à l’identification à un père dominant ; pour M. D, l’introjection manquée à un père fort mais lié à une mère sur qui on ne peut pas compter), tandis que dans la seconde intervention, il a mis en évidence le thème inconscient partagé « ni avec, ni sans toi » (la peur que l’autre s’empare de la relation), qu’ils expriment aussi par leur collusion, au point de déclencher un conflit afin d’exclure l’analyste et d’éviter ainsi de « penser ».
Le mariage est-il une menace pour le couple ?
Authors: Levisky Ruth Blay
Published: April 2012

Résumé L’auteur analyse les transformations dans les relations au sein d’un couple qui, après avoir vécu une passion intense en tant qu’amants, a connu dans le mariage des moments de violence et d’agressivité. Un lien parasitaire s’est alors développé, dominé par le contrôle, la compétitivité et l’impulsivité. Suite à une consultation urgente liée à des violences physiques, la thérapie de couple a mis en évidence un conflit relatif au désir de l’épouse d’avoir un enfant (elle était sans enfant, alors que son mari en avait cinq). Selon son mari, de graves problèmes cardiaques interdisaient une grossesse. Pour elle, un suivi médical aurait rendu la grossesse possible, mais son mari ne supportait pas l’idée qu’un nouveau-né vienne s’immiscer entre eux. Dans cette évolution, était-ce le mariage qui était en cause ? Les changements dans les affects, fantasmes et représentations étaient-ils de l’ordre de la désillusion ? Le processus psychanalytique a facilité les réflexions sur le fonctionnement mental du couple et les réponses de chacun face à la frustration.
Spatiographie familiale
Authors: Cuynet Patrice , Mariage André , Vannier Annick , Puthomme Serge , Roult Philippe , Rossez Christine
Published: April 2012

Résumé L’innovation d’un outil projectif en thérapie familiale psychanalytique, tel que le dessin collectif d’une maison de rêve, va permettre de révéler la structure inconsciente de la représentation du corps familial. C’est la figuration de l’interfantasmatisation familiale qui aide chaque membre à prendre conscience des liens narcissiques qui les solidarisent au groupe ; mais aussi grâce aux places singulières qui les différencient dans cette cohabitation spatiale, ils pourront renforcer leur identité. Par le biais d’un exemple clinique les auteurs montrent comment une crypte peut se révéler à travers un dessin familial.
Anorexie mentale
Authors: Condamin Christine
Published: April 2012

Résumé Certaines familles sont marquées par une dynamique interne de rejet et de séduction : des rapports pathologiques d’autoritarisme, de tyrannie, de contrôle et de manipulation s’instaurent sur plusieurs générations pouvant amener la disqualification et la désubjectivation d’un ou de plusieurs membres. L’auteur illustre son propos par le travail psychanalytique de couple effectué durant cinq années par les parents d’Astrid, jeune fille anorexique de 16 ans.
Faire part d'enfances
Authors: de la Genardière Claude
Published: April 2012

Résumé La violence fantasmatique des adultes et en particulier des parents, exprimée dans certaines représentations collectives de l’enfant, peut frapper, mais elle a toujours existé, comme le montrent notamment les rites d’accueil de l’enfant dans les sociétés traditionnelles ou les cartes postales éditées au moment des guerres (particulièrement celles illustrées de « bébés graines de poilus »). Ces représentations font écho à l’enfant inconscient, tout aussi étrangement inquiétant, que révèle l’expérience psychanalytique, effet d’une violence de l’infantile en nous. Les faire-part de naissance sont aussi porteurs de tels fantasmes infantiles. Des confusions de places apparaissent ainsi dans la mise de l’enfant lui-même en position d’annonceur de sa propre naissance. L’enfant s’y montre alors littéralement autofondé. Dans de tels exemples, ne s’agit-il pas pour les parents de faire part de leur enfance fantasmatique ?
La migration des enfants
Authors: Losso Roberto , Gandolfo Jorge , Horvat Pedro , Leive Bonfiglio Susana , Losso Ana Packciarz
Published: April 2012

Résumé Les auteurs décrivent plusieurs motifs pour lesquels les familles, ou plusieurs de ses membres, peuvent émigrer, de façon temporaire ou permanente. Ils analysent les différences entre les différents projets migratoires, s’ils sont de toute la famille ou non, si c’est pour réalisation personnelle ou groupale, ou bien pour raisons politiques, religieuses, économiques, sociales, raciales ou autres. Les auteurs donnent des précisions sur les caractéristiques de la migration à l’intérieur de l’Argentine. Ils font le commentaire d’un cas clinique, pour illustrer que, bien que la migration implique dans de nombreux cas une métamorphose familiale, comme une étape dans le développement, dans d’autres cas elle n’est pas, comme il paraît, un mouvement de croissance, mais principalement un recours ­défensif.
Les violences intra-familiales en situation d'hétérogénéité culturelle
Authors: Mohamed Ahmed
Published: April 2012

Résumé Les stigmates de la violence physique ou psychologique sont d’autant plus lourds à porter qu’ils sont marqués du sceau du silence, de la honte et de l’humiliation. Un silence bien difficile à briser car la violence semble émerger des modes de fonctionnement familiaux complexes, structurés autour de configurations particulières à la fois intra-psychiques, relationnelles et intergénérationnelles. Parmi les situations de violence intra-familiale envers les enfants, l’appartenance à une culture différente met les professionnels en difficulté dans leurs pratiques quotidiennes. L’auteur pose les jalons d’un questionnement clinique interculturel qui prend racine dans les problèmes que l’étranger et son enfant soulèvent aux institutions éducative, soignante et judiciaire et souligne le rôle et les apports de la TFP dans la prise en charge thérapeutique de ces situations critiques.
Le lien parento-filial comme un lien d'hospitalité
Authors: Kleiman Sonia , Eiguer Alberto , Loncan Anne
Published: April 2012

Résumé Dans quelle optique se place un psychanalyste du lien en ce qui concerne le lien parento-filial ? Est-ce que sa perspective a une spécificité ? S’agit-il d’un autre discours, ou d’une autre manière d’envisager la clinique ? La psychanalyse énonce des hypothèses relatives à la construction du psychisme de l’homme, du monde interne du sujet. Sous l’angle de l’intersubjectif, ce qui interroge, c’est l’imprévisible, ce que la présence de l’autre impose. Le lien parento-filial est ainsi décrit comme lien d’hospitalité. L’hospitalité n’appartient à l’origine ni à l’amphitryon ni à l’invité mais au geste par lequel on le reçoit. Notre réflexion concerne ce lien sans mettre l’accent sur les places et fonctions de la parenté, mais au contraire sur l’expérience nouvelle que la rencontre convoque.
Une analyse psychanalytique de la conjugalité dans les mariages durant depuis 20 et 30 ans
Authors: de Souza Campos Paiva Maria Lucia , Gomes Isabel Cristina
Published: April 2012

Résumé Cet article se base sur un mémoire de maîtrise soutenu en 2003, à l’Institut de Psychologie de l’Université de São Paulo, dont l’objectif était d’étudier les types de relation conjugale (consciente et inconsciente) qui s’établissent dans des mariages dont la durée est de vingt à trente ans ainsi que leurs caractéristiques. L’échantillon de cette recherche a été constitué par trois couples qui ne suivaient pas de psychothérapie, et qui apparemment n’avaient pas de plainte. Les données ont été obtenues par l’intermédiaire d’entretiens semi-directifs avec le couple, le mari et sa femme étant présents. Ensuite on a utilisé le TAT avec chaque conjoint séparément. Le référentiel théorique psychanalytique a été utilisé pour analyser les résultats obtenus. Ainsi, nous avons pu constater que le lien conjugal (conjugalité) s’est perdu au fur et à mesure, surtout après l’arrivée des enfants; quelquefois il a même été difficile de l’établir. Pendant les années de mariage, les conjoints aussi bien que les enfants ont présenté des symptômes. Nous avons pu remarquer que ce qui maintient le mariage est le fait d’avoir formé des couples complémentaires, et non un partenariat dans lequel l’homme et la femme occupent des places équivalentes.
Une affaire de famille
Authors: Sommantico Massimiliano
Published: April 2012

Résumé L’application de la méthodologie psychanalytique au film de Chabrol La Fleur du Mal met en lumière une forme de transmission trans-générationnelle dans une lignée. La transmission du secret, de la honte et de la culpabilité sur trois générations semble empêcher le travail de subjectivation de l’histoire familiale à chaque génération. Nous sommes aussi confrontés, dans le film, à l’importante fonction de la maison familiale comme lieu qui contient la mémoire familiale. L’interrogation qui anime le cinéaste est la suivante : peut-on échapper à un destin déjà écrit ?