bluuebunny/crossref_metadata_2025 huggingface dataset:
Harmonious Biomaterials for Development of In situ Approaches for Locoregional Delivery of Anti-cancer Drugs: Current Trends
Authors: Singh Amrinder , Thakur Shubham , Sharma Tushit , Kaur Manjot , Sahajpal Nikhil Shri , Aurora Rohan , Jain Subheet Kumar
Published: June 2019

Locoregional drug delivery is a novel approach for the effective delivery of anti-cancer agents as it exposes the tumors to high concentration of drugs. In situ gelling systems have fetched paramount attention in the field of localized cancer chemotherapy due to their targeted delivery, ease of preparation, prolonged or sustained drug release and improved patient compliance. Numerous polymers have been investigated for their properties like swelling along with biodegradation, drug release and physicochemical properties for successful targeting of the drugs at the site of implantation. The polymers such as chitosan, Hyaluronic Acid (HA), poloxamer, Poly Glycolic Lactic Acid (PGLA) and Poly Lactic Acid (PLA) tend to form in situ hydrogels and have been exploited to develop localized delivery vehicles. These formulations are administered in the solution form and on exposure to physiological environment such as temperature, pH or ionic composition they undergo phase conversion into a hydrogel drug depot. The use of in situ gelling approach has provided prospects to increase overall survival and life quality of cancer patient by enhancing the bioavailability of drug to the site of tumor by minimizing the exposure to normal cells and alleviating systemic side effects. Because of its favorable safety profile and clinical benefits, United States Food and Drug Administration (U.S. FDA) has approved polymer based in situ systems for prolonged locoregional activity. This article discusses the rationale for developing in situ systems for targeted delivery of anti-cancer agents with special emphasis on types of polymers used to formulate the in situ system. In situ formulations for locoregional anti-cancer drug delivery that are marketed and are under clinical trials have also been discussed in detail in this article.
Ferulic Acid: A Promising Therapeutic Phytochemical and Recent Patents Advances
Authors: Chaudhary Ashun , Jaswal Vivek S. , Choudhary Sonika , Sonika  , Sharma Ajay , Beniwal Vikas , Tuli Hardeep S. , Sharma Sanjeev
Published: June 2019

Background:

Among the various phenolics metabolites, ferulic acid is considered as the
promising mitigating, restorative and antioxidant agent. Ferulic acid is one of the most commonly
found natural products in vegetables, for example, tomatoes, sweet corn, and in rice grain. Phytochemicals
are utilized in the treatment of human ailments and these are derived from the dietary compounds.

Objective:

The present review widely argued the calming restorative capability of ferulic acid alongside
the scientific evidences and its proposed mechanism for activity. Furthermore, we provided the main
practical points for the use of ferulic acid in oxidative damages during various diseases. Additionally,
the relevant patents on ferulic acid with various therapeutic potential has been discussed.

Methods:

One hundred and twenty references have been cited in the present review article. The cited
references were found to be suitable and described the therapeutic application of ferulic acid thoroughly.

Conclusion:

Ferulic acids are known to contrarily down-manage an assortment of extracellular and
intrcelullular molecular targets related to infection movement. Various patents on ferulic acid based
moieties have been accounted for from 2018. The ferulic acids have a wide scope of impacts against
different infections like malignant growth, diabetes, cardiovascular and neurodegenerative diseases.
The current review deals with the antioxidant property of ferulic acid and the recent patent describes
the role of ferulic acid against human diseases.
Antiphospholipid Syndrome (APS) - An Update on Clinical Features and Treatment Options
Authors: Katikaneni Mamatha , Gangam Meera , Berney Seth Mark , Umer Sarwat
Published: June 2019

Antiphospholipid syndrome (APS) is an autoantibody disorder characterized by the presence of antiphospholipid (APL) antibodies and heterogeneous clinical manifestations. Patients may present with recurrent thrombosis, obstetric morbidity, cardiac valvular lesions, thrombocytopenia, skin lesions, renal or neurologic abnormalities. We provide a comprehensive review of these diverse clinical features except renal and obstetric complications. Treatment of APS can be challenging as one tries to balance the benefit of anticoagulation therapy in this hypercoagulable state while minimizing the risk of bleeding. We discuss the various therapeutic options including the role of aspirin, warfarin, low molecular weight heparin, new direct thrombin inhibitors, hydroxychloroquine, intravenous gamma globulin, rituximab and others. Lower risk APS patients (i.e. first venous thrombosis) should receive warfarin with a target INR of 2.0-3.0. Higher risk patients (i.e. arterial thrombosis or recurrent venous events) have a target INR of >3.0. Currently, warfarin remains the mainstay in treatment of APS. Because of lack of adequate data, the newer oral direct inhibitors should be considered only when there is a known allergy/ intolerance or poor control with warfarin. Additional vascular and thrombotic risk factors should be aggressively reduced. Further studies involving large number of APS patients, diagnosed according to accepted criteria, are needed to better define the role of newer anticoagulants and other novel therapies.
Diagnosing Diabetes Mellitus With Glycated Haemoglobin in Newly Diagnosed HIV-positive Patients in Buffalo City Municipality, South Africa: A Cross-sectional Study
Authors: Sogbanmu Olufunso O. , Obi Larry O. , Goon Daniel T. , Okoh Anthony , Iweriebor Benson , Nwodo Uchechukwu. U. , Ajayi Anthony I. , Digban Tennison O.
Published: June 2019

Background:

The HbA1c estimates long-term glycaemic control in individuals. However, scanty data exist on the determination of Diabetes Mellitus (DM) in newly diagnosed HIV patients using the HbA1c screening tool in the South African context. Thus, this study examines the prevalence of diabetes mellitus in newly diagnosed HIV-positive patients in Buffalo City Municipality, East London, South Africa.

Methodology:

This was a cross-sectional study of 335 newly HIV-diagnosed patients between August 2016 and July 2017. Demographic (age, gender, residence, employment status and level of education) and behavioural variables (smoking and alcohol use (past 30 days)) were by self-reporting. Information on HbA1c and other clinical variables were obtained from the medical records of the patients. Diabetes mellitus was defined based on the Society for Endocrinology, Metabolism and Diabetes of South Africa (SEMDSA) 2017 guideline of HbA1c of above 6.5%. Weight and height were measured using standard protocols. Logistic regression analyses were applied to determine the predictors of abnormal glycated haemoglobin.

Results:

Majority of the participants were female (72%). The prevalence of patients with HbA1c greater than 6.5% was 6%. The multivariate analysis indicates only age (p=0.031) and race (0.019) significantly shows a correlation to increase the risk of development of DM in newly diagnosed HIV positive patients. The binary logistic regression analysis shows that age (above 46 years) (p=0.001; AOR (6.60); CI (2.08-20.9) was directly related to the development of DM.

Conclusion:

Consistent with other studies, the exclusive non-fasting HbA1c, which is a marker of glycaemic control, only underestimate glycemia in HIV patients with diabetes in this present study. Notwithstanding, HIV patients who are over 40 years are likely to develop DM. As such, screening older individuals diagnosed with HIV is crucial in offering a timely point of care and interventions.
THE CONCEPT DESIGN OF OBSERVATION CONTROL SYSTEM FOR LIJIANG 2.4-METER TELESCOPE
Authors: Wang C. J. , Chen L. X. , Fan Y. F. , Wang D. Q.
Published: June 2019

The Lijiang 2.4-m telescope was built and opened to astronomers since 2008, now there are several instruments installed at the telescope. The control system of the 2.4-m telescope was designed to be operated in robotic mode as the Liverpool telescope, but due to many reasons it didn’t achieve robotic mode until now. After we upgraded the fold mirror by adding a rapid instrument exchanging system at the Cassegrain focus in 2012, now we can have up to 9 instruments on the telescope at the same time, but the control system for the instrument is still specific for each instrument. During the observation, change to different control software and operating system for different instrument are needed, which affects the observation significantly. Following the observation control system for few years, we are trying to develop a suitable observation control system for the Lijiang 2.4-m telescope. In this paper, we will introduce the Lijiang observatory, the 2.4-m telescope and its instruments at first, and then discuss the concept design of observation control system for this telescope which will based on the main purpose of improving the observation efficiency.
Changes in Tear Cytokines Following a Short Period of Daily and Overnight Silicone Hydrogel Lens Wear
Authors: Duong Kim , Chao Cecilia , Willcox Mark , Richdale Kathryn
Published: June 2019

Background and Objective: To investigate changes in ocular surface inflammatory markers after daily and overnight silicone hydrogel contact lens wear in healthy wearers.

Material and Methods: Twenty-six experienced soft contact lens subjects were evaluated at baseline, after 1-day of silicone hydrogel lens wear, and after 1-night of wear. Basal tears were collected at each visit and tear cytokine concentrations were quantified using multiplex [interleukin (IL)-1β, IL-6, IL-10, IL-12(p70), IL-17A and tumor necrosis factor (TNF)-α] or ELISA (IL-8) kits. A historical control group of 27 non-contact lens wearers was used to compare absolute concentrations and diurnal variations in tear cytokine concentrations. Changes in cytokine concentrations were analyzed using linear mixed models. Linear regression with bootstrapping was used to assess whether changes in IL-1β concentrations were associated with changes in other cytokines.

Results: IL-8 concentrations decreased after 1 day of silicone hydrogel contact lens wear and returned to baseline levels the next morning (p=0.04). This same diurnal fluctuation was seen in non-contact lens wearers (p=0.03). With daily contact lens wear, there was a significant positive correlation between the changes in IL-1β and IL-8, TNF-α, IL-10 and IL-12(p70) (all p<0.03). With overnight contact lens wear, there were significant positive correlations between the changes in IL-1β and IL-6, IL-17A and TNF-α (all p<0.01).

Conclusion: A short period of daily and overnight silicone hydrogel lens wear does not significantly alter the inflammatory status in adapted soft contact lens wearers.
Conjunctival Inlapse: Nasal and Temporal Conjuctival Shape Variations associated with Scleral Lens Wear
Authors: Courey CLaudine , Courey Gabriella , Michaud Langis
Published: June 2019

PURPOSE: This article aims to report a new clinical finding associated with the wear of scleral lenses.

METHODS: Non-contact lens wearer subjects were recruited and fitted with large diameter (18 mm) scleral lenses. Lens was randomly filled with non preserved saline or non preserved carboxymethylcellulose-based artificial tears (Refresh Celluvisc, Allergan, Ca). The sinking of the lens on the nasal and temporal sclera was assessed periodically during a total of 6h00 of wear, with the use of anterior segment coherence tomography (OCT- Optovue, Clarion Technologies, Texas).   Images were taken every 30 minutes for the first 2h00, then at 4h00 and 6h00 post-insertion.

RESULTS:  The nasal side sinks significantly more than the temporal side by 23.0±7.3 μm (F(1,12)=10.043; p=0.008; 95%CI:[7.2 ,38.9]). This difference is significant with time (F=8.757; p<0.001) and there is a side effect (F=10.043; p=0.008). The type of solution does not influence the lens behavior (F=0.250; p=0.626).  A new clinical finding was revealed during scan analysis. Conjunctival tissue displacement was seen, under the reverse curve of the scleral lens, shortly after insertion. This conjunctival “inlapse” (CI) was sustained over all the wearing hours. On the nasal quadrant, CI was reduced in height and present in only 8/15 subjects while, in the temporal quadrant, 100% of subjects showed an average CI of 38.39 ± 10.43 μm (t(84)=3.68; p=0.0072; 95%CI[17.64, 59.13]) 30 minutes post insertion followed by a non-significant decrease of 1.97 ± 10.34 μm (t(84)=0.19; p=1.00; 95%CI[-22.52,18.58]) between 30 minutes and 6 hours of wear.

CONCLUSION: Nasal sinking is more pronounced as compared with temporal lens sinking. This may explain the occurrence of a new clinical phenomenon identified to happen shortly after lens insertion, under the reverse curve of a scleral lens. In fact, CI happens mostly on the temporal quadrant, where more space is available for the conjunctival tissue to move. This finding suggests that conjunctival tissue reacts to scleral lens wear, not only in the inferior quadrant, where conjunctival prolapse is known to occur, but in every other one as well.
On the use of remote sensing in the design of Railways
Authors: Andreeva O.A. , Konon N.I. , Ratinski M.G.
Published: June 2019

The authors analyze the methods of engineering-geodetic and design of Railways in remote and sparsely populated areas. It is shown that one of the ways to improve the efficiency of design work significantly, especially for the design of roads in sparsely populated regions is the use of remote sensing materials and geoinformation technologies that enable you to apply the methods of geospatial and geological analysis, modeling and forecasting with the use of software and hardware systems of information support in design of Railways on the basis of computer geological interpretation of space survey materials. The problems of integrating geoinformation technologies in the system of computer-aided design of Railways are considered. The tasks of improving modern methods of engineering researches are set. This will significantly reduce the time and financial costs in the design, and rise the efficiency of engineering surveys.
Tuning the copper Cluster´s size on HOPG by electrodeposition from perchlorate aqueous solutions. An AFM study
Authors: Garcia-Rodriguez Diana , Rios Reyes , Mendoza Huizar
Published: June 2019

In this work, we report the electrochemical synthesis of nanometric copper clusters smaller than 3 nm of height and 14.3 nm of diameter from perchlorate solutions. From the number of copper clusters counted directly from the AFM (Atomic force microscopy) images, it was possible to derive an equation, which is able to predict the number of clusters formed in function on the applied potential. Also, qualitative AFM images were simulated employing a spreadsheet and the freeware ImageJ, the results obtained show concordance with the experimental AFM images.
Oxovanadium(IV) complexes of the pyridoxal Schiff bases: Synthesis, experimental and theoretical characterizations, QTAIM analysis and antioxidant activity
Authors: Ghorbani Parisa , Ali Beyramabadi , Homayouni-Tabrizi Masoud , Yaghmaei Parichehreh
Published: June 2019

Two vanadyl complexes of the pyridoxal Schiff bases have been newly synthesized and characterized by several experimental methods, where the 4,4?-[1,4-butanediylbis-[(E)-nitrilomethylidyne])bis[5-hydroxy-6-methyl- -3-pyridinemethanol] and trans-4,4?-[1,2-cyclohexanediylbis-[(E)-nitrilo-methylidyne]] bis[5-hydroxy-6-methyl-3-pyridinemethanol] Schiff base were used. Geometry optimization, assignment of the IR vibrational frequencies and the natural bond orbital (NBO) analysis of the complexes have been calculated by employing the density functional theory (DFT) approaches. Deprotonated form of the Schiff bases (L2-) acts as a tetradentate N2O2 ligand, which coordinates to the V(IV) via two phenolate oxygens and two imine nitrogens. In the square?pyramidal geometry of the [VO(L)], the apical position is occupied by an oxo ligand. The DFT-calculated vibrational frequencies show a good consistency with the corresponding experimental values, confirming suitability of the optimized geometries for the complexes. Characteristics of the bonding interactions have been explored using the quantum theory of atoms in molecule (QTAIM) analysis. The complex formation results in decrease in strength of the C?N bond of the azomethine group and increase in the strength of the C?O bonds of the phenolate group. High-energy gaps approve stability of the complexes. Both of the complexes show significant radical scavenging activities against the ABTS and DPPH radicals, even higher than the BHA.
Spatial distribution of PAHs in riverbed sediments of the Danube river in Serbia: Anthropogenic and natural sources
Authors: Brboric Maja , Vrana Branislav , Radonic Jelena , Vojinovic-Miloradov Mirjana , Turk-Sekulic Maja
Published: June 2019

The top layer of riverbed sediments from 10 sites along the Danube River in Serbia were analysed for the presence of polycyclic aromatic hydrocarbons (PAHs). Potential sources of pollution were identified using different multivariate techniques. Total concentrations of 29 PAHs in sediment samples ranged from 128.27 to 676.85 ?g/kg dry weight. Based on these concentrations and PAH patterns, a clear spatial distribution of examined localities was determined. The diagnostic ratios indicated a pyrolytic origin of PAHs, except for two sites where PAH contamination originated from petrogenic sources. The Varimax rotated principal component analysis revealed three main factors, namely coal, wood, and biomass combustion; vehicular emissions; and natural sources; accounting for 92.1 % of the variance in the original datasets. The sites with different pollution load, depending on main sources identified, were arranged by hierarchical cluster analysis. The results were compared with sediment quality guidelines, and the obtained values of equilibrium partitioning sediment benchmarks toxic unit and total toxic equivalent quantities of benzo- [a]pyrene suggested that Danube sediments do not pose an elevated ecotoxicological risk for benthic organisms.
X-ray calibration of Dee voltage of radiofrequency cavity based on a low-power test
Authors: Liu Guang , Song Yuntao , Chen Gen , Zhao Yanping , Caruso Antonio , Calabretta Luciano , Zhang Xin
Published: June 2019

Radiofrequency cavity is one of the most critical and complicated components in a cyclotron. Dee voltage of radiofrequency cavity accelerates charged particles to achieve required energy. Peak voltage of Dee is the key parameter of an radiofrequency cavity. Balanced Dee voltage is very important for effective beam cantering and beam extracting. An X-ray measurement has been made to calibrate and verify the peak voltage of Dee in a low-power ( 20 kW) test. The X-ray measurement for radiofrequency cavity was designed by means of bremsstrahlung. A suitable shielding cover was chosen for radiofrequency cavity and the X-ray measurement design was demonstrated according to the theory of photon transmission. Finally, the peak voltage of Dee was obtained at the power of 10-20 kW and the balance of Dee voltage was verified.
The Best Estimate Plus Uncertainty approach in nuclear reactor safety and licensing: Brief history and the elements after licensing
Authors: D’Auria Francesco , Galassi Giorgio
Published: June 2019

The best estimate plus uncertainty is, at the same time, an approach, a procedure and a frame- work in nuclear thermal-hydraulics and nuclear reactor safety and licensing. The motivation at the basis of the best estimate plus uncertainty is the lack of knowledge in the areas of single and, mainly, two-phase transient thermal-hydraulics. In other terms and introducing some simplifications, the insufficient knowledge of turbulence imposes the design of roadmaps for the application of imperfect (thermal-hydraulic) models to the evaluation of design features and of safety for complex technological installations or systems like the nuclear power plants and, more specifically, the water cooled nuclear reactors. Furthermore, the legal counterpart of nuclear reactor safety, or the licensing, is concerned: therefore the best estimate plus uncertainty must account for rules and regulations derived from the fundamental radioprotection principle which imposes the minimization of the impact of radiations upon humans and the environment under any circumstance. In the present paper, the key elements of the approach are identified and characterized. These shall be seen as the support for a consistent application of thermal-hydraulics to the design and safety of water-cooled nuclear reactors.
Incidence of bronchopulmonary dysplasia and mortality of very low birth weight infants in Vojvodina
Authors: Vilotijevic-Dautovic Gordana , Doronjski Aleksandra , Vijatov-Djuric Gordana , Bjelica Milena
Published: June 2019

Introduction/Objective. The incidence of bronchopulmonary dysplasia (BPD) varies depending on the prematurity rate, definition, and therapy that are applied at a certain center. The average incidence of BPD for very low birth weight infants (VLBW) in developed countries ranges 4?53%. The mortality of VLBW infants is high and represents 50% of the total neonatal and infant mortality. In recent years, the survival limits are shifted towards lower gestations. The aim of our study was to determine the incidence and severity of BPD in VLBW infants in Vojvodina and the overall mortality. Methods. This retrospective study was conducted from January 2006 to December 2011 and included 504 infants with birth weight < 1,500 g. Results. In the total premature infants? population, 82.3% survived by the gestational age of 36 weeks. According to the original definition of BPD, as supplemental oxygen use at 28 days of life, BPD had 45.4% of infants. According to the severity based definition 19.4% had mild BPD, 19.8% moderate BPD and 6.5% severe BPD. If BPD is observed as supplemental oxygen use at 36 weeks postmenstrual age, BPD had 26% of infants. Conclusion. The overall mortality and incidence of BPD in our study are comparable to those in some developed countries and lower compared to underdeveloped countries.
100Cr6 Çeliğinde Kısmi ve Tam Östenitlemede Karbür Çözünmesi Kinetiği
Authors: ERİŞİR Ersoy , GEZMİŞOĞLU Ahmet Efe
Published: June 2019

Bu
çalışmada, 100Cr6 çeliğinde kısmi ve tam östenitleme koşullarında sementit
çözünme kinetiği incelenmiştir. 840 °C ve 1050 °C sıcaklıkta farklı sürelerde
ısıl işleme tabi tutulan numunelerde sementit hacim oranındaki ve boyutundaki
değişim belirlenmiştir. ImageJ yazılımı ile SEM mikrografları analiz edilerek
karbürlerin boyutu ve hacim oranları belirlenmiştir. Elde edilen istatistiksel
veriler “lineer olmayan eğri uydurma” yöntemi kullanılarak çözünme eğrilerine
dönüştürülmüştür. Tam ve kısmi östenitleme işlemlerinin başlangıcında sementit
çözünme hazının yüksek olduğu belirlenmiştir. Bir model kurularak DICTRA
yazılımında karbür çözünmesi hesaplanmıştır. Elde edilen çözünme eğrileri
DICTRA sonuçları ile karşılaştırılmıştır. SEM mikrograflarından elde edilen
istatistikler ile DICTRA hesaplamalarının uyumlu olduğu görülmüştür. Elde
edilen hesaplama sonuçlarına göre başlangıçtaki hızlı karbür çözünmesinin
nedeni, C atomları difüzyonu ile kontrol edilen ve Cr difüzyonunun ihmal
edildiği “ihmal edilebilir yerel denge” modunda çözünmenin gerçekleşmesidir.
Faktor-Faktor Pemicu Minat Mahasiswa Menjadi Wirausaha (Studi Empiris di Universitas Hindu Indonesia)
Authors: Pramuki Ni Made Wisni Arie , Pratiwi Komang Ary , Purwaningrat Putu Atim
Published: June 2019

Students participate actively in the development of the nation with a hope not only as job seekers, but also as providers or creators of employment by becoming entrepreneurs. Entrepreneurship entry into the college curriculum is expected to provide graduate competencies with hardskills and entrepreneurial softskills. But the low interest of students to become entrepreneurs is the motivation and attractiveness of researchers to conduct further studies. Thus, it is very important to know what factors can encourage students as triggers to become entrepreneurs. This research was carried out with the aim to identify factors that could trigger entrepreneurial interest in students, especially at the Faculty of Economics, Indonesian Hindu University. The analysis was carried out on the data obtained from the primary data by using questionnaire instruments to 100 students which included factor analysis and regression analysis. Factor analysis test results obtained evidence that the main factors that can trigger student interest into entrepreneurship can be grouped into three factors, namely attitudes, image and financial motivation. While the regression analysis obtained evidence that the three factors namely attitudes, image and financial motivation have a positive and significant influence on the interest of students to become entrepreneurs. Thus awareness programs for entrepreneurship need to be carried out more efficiently and effectively, so that our next generation is more as a creator of employment than a job seeker.
Erosión hídrica por lluvias máximas en diferentes tiempos de retorno en la subcuenca Cumbaza - Región San Martín
Authors: Camacho-Zorogastúa Katherine , Gomez-Lora Walter
Published: June 2019

La subcuenca Cumbaza cuenta con la mayor cantidad de áreas boscosas (bosques primarios) deforestadas, lo que ha generado el incremento de la erosión hídrica en los suelos. La presente investigación tuvo como objetivo conocer la erosión hídrica en función de las lluvias máximas para diferentes tiempos de retorno mediante el Modelo de la Ecuación Universal de Pérdida de Suelos y el modelamiento de los Sistemas de Información Geográfica (SIG), a fin de proponer medidas de conservación de suelos. Se realizó una investigación empírica de diseño no experimental, para lo cual se evaluaron las lluvias máximas en 24 horas mediante la regional- ización hidrológica utilizando el método Gumbel Tipo I para conocer la distribución de las lluvias en Cumbaza. Luego se evaluaron cartográfi- camente las trece (13) áreas de vulnerabilidad erosiva usando el mod- elamiento SIG realizando una ponderación, del cual el 23,2% del total de área presenta una vulnerabilidad erosiva alta, mientras que el 58,1% tiene una vulnerabilidad media, y un 12,1 y 6,6% poseen vulnerabilidad baja y muy baja, respectivamente. Asimismo, se estimó la tasa de erosión hídrica mediante el modelo USLE, resultando valores de 31, 40 y 50 t/ ha/año para un tiempo de retorno de 5, 25 y 100 años respectivamente; y finalmente se formuló una propuesta para la conservación de suelos uti- lizando Sistemas Agroforestales a través de la reforestación con especies nativas en función al tipo de suelo, clima, altitud, costos, etc., para lo cual se utilizaron árboles y arbustos nativos como aguaje, bambú caoba, ojé y sacha inchi.
Alteridad identitaria en los protagonistas de La ciudad y los perros (1963): ¿héroe o antihéroe?
Authors: Delgado Del Aguila Jesús Miguel
Published: June 2019

Los protagonistas de La ciudad y los perros (1963) están inmersos en un juego cíclico de recorrer los estados del miedo y la autoconfianza cuando ocurre una pelea; es decir, una manifestación de violencia. Por ejemplo, se demostró que el Esclavo no tuvo temor al denunciar al serrano Cava, a pesar de que sabía que el Círculo y el Jaguar podían vengarse de él; también, se probó un caso contrario, el Jaguar se arrepintió de haber asesinado (adoptó una postura disfórica de culpabilidad y necesidad de cambiar).
Tecnología de realidad aumentada para el proceso de enseñanza-aprendizaje en el Perú
Authors: Flores Masías Edward José
Published: June 2019

La realidad aumentada (RA) en el Perú y en el mundo no es nueva, tiene sus orígenes principalmente en la década de los noventa, es una tecnología de información y comunicaciones muy utilizada en diversos entornos socio-económicos y también en el contexto educativo, permite identificar información adicional al entorno real de la cual se visualiza o se describe, de esta forma, puede llegar así de manera más rápida a la persona o grupo de personas información relevante para su conocimiento o para establecer una relación cercana con alguna actividad en particular. En la actualidad, la RA es considerada una fuente muy importante y necesaria de información y de fácil acceso para interactuar con el ser humano, incluso, en muchos casos, esta ha sido desarrollada en juegos para niños y adultos de todas las edades, de tal forma que puedan interactuar y aprender cada vez con mayor facilidad frente al avance constante de las tecnologías de información. El presente trabajo describe la RA, las expectativas posibles de comunicaciones para su uso, y los principales desarrollos en investigaciones realizadas hasta el momento para la educación en el Perú.
Esquemas emocionales y dependencia emocional en estudiantes de Psicología de universidades de Lima Metropolitana
Authors: Aguirre Morales Marivel , Cirilo Acero Ingrid , Brocca Alvarado Paul
Published: June 2019

Se investigó la relación entre los esquemas emocionales y dependencia emocional en universitarios de Lima. Los participantes fueron estudiantes de universidades públicas y privadas, entre hombres y mujeres con un total de 451. Los instrumentos usados fueron la Escala de Esquemas emocionales de Leahy adaptado en su estructura por Aguirre, Cirilo, Brocca (2017) en muestra universitaria. Y el instrumento de Escala de dependencia emocional-ACCA. Los resultados específicos del esquema emocional respecto al sexo muestran diferencias solo en el esquema insensibilidad a favor de los hombres. Respecto a la edad y la procedencia, se observa las diferencias significativas en la mayoría de los esquemas. Para la dependencia emocional existen diferencias según la universidad que procede. Se evidenció correlaciones entre los esquemas y la dependencia emocional de magnitud baja y negativas en su mayoría, sin embargo, altamente significativas. Finalmente, entre los primeros hallazgos de estas correlaciones se comprendería que los universitarios no entenderían sus emociones dificultándoles afrontar adecuadamente y no clarificando sus valores cuando está la tendencia hacia la necesidad de afecto extremo.
Moralidade, Etica, Autonomia e Educação
Authors: Bellini Luzia , Ruiz Adriano
Published: June 2019

Relata a investigação desenvolvida no período de agosto de 1994 a julho de 1996, intitulada Adultos Trabalhadores em Processo de Alfabetização: um Estudo sobre a Inteligência Prática e a Autonomia Moral, e traz reflexões sobre as representações da escola e do conhecimento e sobre as condutas cognitivas, éticas e morais de um grupo de alunas do Projeto de Alfabetização de Adultos da Universidade Estadual de Maringá (UEMPR). As idéias apresentadas orientam-se em estudos piagetianos sobre a inteligência prática e a construção da moral e suas relações com o processo de escolarização.

Abstract

In this article the investigation carried out from August/1994 to July/1995 called Adult workers in the process of literacy: a study on practical intelligence and moral autonomy is reported. It presents some reflections on school and knowledge representations and on cognitive, ethical and moral behaviours of a group of student from the Adult Literary Project of Universidade Estadual de Maringá(UEM-PR). The ideas discussed are based on Piaget's studies about practical intelligence and moral construction and their relations with the learning process.

Résumé

Cet article rapporte une recherche développée dès du mois d'août 1994 à juillet 1996, sous le titre Adultes travaileurs en procès d'alphabétisation: une étude sur l'intelligence pratique et l'autonomie morale. Il s'agit d'une reflexion sur les représentations de l'école, de la connaissance et des démarches cognitives, éthiques et morales d'un groupe d'élèves qui font partie d'un projet d'alphabétisation d'adultes de l'Universidade Estadual de Maringá (UEM-PR). Les idées présentées sont basées sur des études de Piaget à propos de l'intelligence pratique et de la construction de la morale et leurs relations avec le procès de la scolarisation.

Resumen

En este artículo se relata la investigación desarrollada en el período de agosto del 1994 a julio del 1996, o título Adultos trabajadores en proceso de alfabetización: un estudio sobre la inteligencia práctica y la autonomia moral. Traza reflexiones sobre las representaciones de la escuela, del conocimiento y sobre las conductas cognitivas, éticas y morales de un grupo de alumnas del Proyecto de Alfabetización de Adultos de la Universidade Estadual de Maringá (UEM-PR). Las ideas presentadas se orientan en estudios piagetianos sobre la inteligencia práctica y la construcción de la moral y sus relaciones con el proceso de escolarización.
A Educação no Contexto das Mudanças
Authors: Xavier Odiva
Published: June 2019

Apresenta parte de estudos teóricos, realizados no Núcleo de Pesquisa "Currículo e Formação " do Programa de Pós-Graduação em Educação da PUCSP, no primeiro semestre de 1997. A análise, não conclusiva, toma por base a literatura revisada. Busca compreender o que seja mudança, modernidade e pós-modernidade, procurando refletir sobre as grandes transformações que estão ocorrendo no mundo e os novos enfoques das políticas de desenvolvimento, que impõem reorientação à ação educativa e trazem implicações para os sistemas de ensino e para a formação de educadores, gestores e demais profissionais da educação.

Abstract

This paper presents part of the theoretical studies, made in the Investigation Center "Curriculum and Formation " of the Post-Graduation Program in Education at PUCSP, in the first semester of 1997. The analysis, no conclusive, takes as basis the revised literature. It tries to understand what are changes, modernity and post-modernity, meditate on the big changes happening in the world and the new emphasis on development policies, that impose a re-orientation to the educational action and bring implications to the teaching systems and to the formation of educators, managers and other education professionals.

Résumé

Le travail présente une partie d'études théoriques, réalisés au Centre de Recherche "Curriculum et Formation " du Programme de Post-Graduation en Éducation de la PUCSP, au premier semestre de 1997. L'analyse, pas encore conclue, ayant comme base la littérature revisée, cherche à comprendre ce qu 'on conçoit par changement, modernité et post-modernité. Il s'agit aussi d'une réflexion sur les transformations qui ont lieu dans le monde, la manière comment ces transformations se donnent d'après les optiques nouvelles des politiques de développement, qui imposent une reorganization à l'action éducative en apportant des implications pour les systhèmes d'enseignement et encore à la formation d'éducateurs et professionnels d'éducation en général.

Resumen

Ese trabajo presenta parte de estudios teóricos hechos en el Núcleo de Investigación "Currículo y Formación " del Programa de Posgraduación en Educación de la PUCSP, en el primer semestre de 1997. El análisis, no conclusivo, toma por base la literatura revisada. Tenta comprender lo que sea cambio, modernidad y posmodernidad, buscando reflejar respecto a las grandes transformaciones que están ocurriendo en el mundo y los nuevos enfoques de las políticas de desarrollo, que imponen reorientación a la acción educativa y traen implicaciones para los sistemas de enseñanza y para la formación de educadores, gestores y demás profesionales de la educación.
Usage of Simulations and Language Games in ESL Classes
Authors: Sarpparaje M.
Published: June 2019

As we all know that the need to access information continues to grow exponentially and institutions cannot remain as mere venues for the transmission of a prescribed set of syllabus from teacher to student over a fixed period of time, rather they must promote the acquisition of knowledge and skills as a continuous process throughout life span. It has been rightly said by a futurist, „The illiterate of the 21st century ―Will not be those who cannot read and write, but those who cannot learn, unlearn & relearn‟. Hence, the traditional lock-step approach to language teaching is rapidly becoming inadequate in modem teaching-learning process (Lee: 1965). It‟s a recent mandatory call that once unidirectional teaching methodology must be transformed to two way learning process and learner centered as well. This is possible only with interactive classes. But even today ESL learners‟ reluctance to speak English in the classroom is a problem found in almost every language learning environment. Many students are afraid to communicate in English for fear of committing mistakes and in turn getting laughed at by their peers.
Nationalism in Rabindranath Tagore Plays
Authors: Sankar G.
Published: June 2019

History reveals that institutions or artifacts produced by human beings can lead to the exploitation or the loss of freedom of other human beings. Thus the celebration of the good life of an Athenian citizen in Plato‟s time can hide the wretchedness of vast numbers of slaves whose labor made it possible for the few free citizens to enjoy that good life. Our criteria then must apply to all, or at least the vast majority of the vast of the human group concerned, if they are to lay claim to universality. Amiya Kumar Bagchi, Perilous Passage1 The story of Indo-Anglican literature is the story of yesterday, of a little more than a century, and today. One of the natural results of the British rule in India is the rise and development of literature. The term “Indo-Anglican” was first used in 1883 when a book published in Calcutta that bore the title Indo-Anglian Literature. After the publication of two books by Dr.K.R.Srinivasa Iyengar, the term “Indo-Anglian” has not only acquired considerable currency, but also has come to stay as a familiar and accepted term applied to Indian contribution to literature in English. This has come to be known as Indo-Anglian writing and has been quite an active school of didactic and creative art for at least a century. The first theatre offering English language drama in 1776, Indian drama in English has never achieved the same status as Indian fiction and poetry in English. As in other colonies such as Canada, the Indian theatrical scene was dominated by foreign companies, touring plays drawn mainly from
ART FOR LIFE’S SAKE
Authors: RAJARAO Mr. G. , SRINIVAS Prof. V
Published: June 2019

The first half of the 20thcentury is one of the most turbulent eras in the history of English literature. Modern Age marks a sharp and clear departure from the self-complacency, and stability of the Victorian period. The transition from the old to the new, from blind faith to rational thinking is very interesting. The twentieth century is called the Age of Interrogation and Anxiety because the scientific revolution and changing social, moral, political and economic conditions have shaken man’s faith in the authority of religion and church. The persistent mood of skepticism and interrogation has increased disproportionately in want of a new set of values. In the Modern Age number of writers rejected the doctrine of “art for art’s sake”. They developed the new literacy creed of “art for life’s sake” or, at least, for the sake of the community. A much stronger claim to be modern was made by Shaw with his socialism, H.G. Wells with his science fiction and Rudyard Kipling with his empire building and steam engines. The growth of a restless desire to probe and question changed the beginning of the twentieth century. Bernard Shaw vigorously attacks the “old superstition of religion” and the “new superstition of science”. The effect of his writing was to spread abroad for at least a generation “The Interrogative habit of mind”.
Quintessence of Truth and Beauty in the Writings of Rabindranath Tagore and Keats A Comparative Analysis
Authors: Debnath Swati Rani
Published: June 2019

In literary works, truth and beauty have been expressed in a varied number of ways by authors of all genres. Rabindranath Tagore and John Keats, two prominent writers from two languages have linked beauty and truth in philosophical manners in many of their writings. Beauty and truth are not separate entities; they flow from the same spring. Tagore views beauty as linked to eternal characteristics of nature and truth is associated with it. Keats sees beauty from spiritual perspective and according to him, realization of truth leads to the fulfillment of beauty. Readers of Tagore and Keats get eye-opening insights from the viewpoints that are followed by their expressions in regarding the tenets of truth and beauty. Truth and beauty fulfill each other in their harmonious existence in the universe. The authors make us realize that beauty does not emanate merely from sensual pleasure; it is an abstract idea, a spiritual understanding that originates from rhythmic attachment with truth. This article compares and contrasts philosophies of truth and beauty from the writings of Tagore and Keats. In doing so, the paper investigates the literary works of the two writers and explores how they have philosophized truth and beauty in the domain of human thought as well as in the realm of spiritual discipline.
The Theme of Silence in Shashi Deshpande’s That Long Silence
Authors: Mishra Divya
Published: June 2019

This article deals with one of Deshpande’s most significant novels, That Long Silence. In studying the novel from a feminist point of view, an effort has been made to study Deshpande’s psychological insights into the Indian woman’s behaviour. This novel deserves much attention as it is generally considered to be amongst her best and has been singled out among her novels by the Sahitya Academy’s prestigious award in the year 1990.Key words: Discrimination, predicament, dilemma, patriarchy, subjugation.
Aravind Adiga’s The White Tiger: A Socio –Political Study of Poverty and Injustice
Authors: Ahlawat RASHMI
Published: June 2019

Aravind Adiga’s Man Booker Prize winning debut novel The White Tiger is sharp, fascinating, attacks poverty and injustice. The White Tiger is a ground breaking Indian novel. Aravind Adiga speaks of suppression and exploitation of various sections of Indian society. Mainly a story of Balram, a young boy’s journey from  rags to riches, Darkness to Light transforming from a village teashop boy into a Bangalore entrepreneur. This paper deals with poverty and injustice. The paper analyses Balram’s capability to overcome the adversities and cruel realities. The pathetic condition of poor people try to make both ends meet. The novel mirrors the lives of  poor in a realistic mode. The White Tiger is a story about a man’s journey for freedom. The protagonist   Balram in this novel is a victim of injustice, inequality and poverty. He worked hard inspite   of his low caste and overcame the social hindrance and become a successful entrepreneur. Through this novel Adiga portrays realistic and painful image of modern India. The novel exposes the anxieties of the oppressed.
A REVIEW ON DIFFERENT APPLICATIONS OF SOLAR CHIMNEY
Authors: Gwatiya Arvind
Published: June 2019

Most recent couple of decades the vitality interest is ascending for space warming and cooling, in private and business building distinctive sorts of hardware, techniques, trial setup are utilized to lessen vitality request and for diminishing utilization of vitality numerous sorts of renewable wellsprings of vitality are likewise used to decrease vitality request and spare environment by various sorts of poison. Most normal renewable wellsprings of vitality is sunlight based vitality which is utilized as a part of this exploratory as Solar Chimney. In this proposal, we utilize solar chimney for Natural Room Ventilation framework amid summer season. Solar Chimney is utilized for its incorporated Design, Low cost of upkeep, Easy to utilize. This is recipient for the carbon dioxide outflow necessity of vitality and interest of vitality, starting the expense of operation. In this paper, we discuss about different solar chimney application in previous years.
“A DNA MOLECULE” OF CONTINUING PROFESSIONAL EDUCATION SERVICES AS ELEMENT OF MARKETING STRATEGY OF IMAGE CREATING
Authors: Voziyanova Natalya Yurievna , Chugunkina Irina Vladimirovna
Published: June 2019

The article focuses on the analysis of theoretical aspects of creating marketing strategies of the continuing professional education (CPE) institutions, where the most important strategies of creating and developing CPE image are: organizational and institutional strategy; product strategy; communication strategy. When forming the product strategy it is expedient to rely upon interdisciplinary and institutional approaches. A basic model for developing marketing strategies of creating the image of CPE services is the product strategy, whose basis should contain “a DNA molecule” of CPE services. Supported by the principles of the new institutional economic theory that defines the approaches to forming the institutes as sets of norms and rules, mechanisms of their realization, guarantees and responsibilities for their failure, considering the limited rationality of a person, there has been substantiated the need to account cognitive and other features of the educational service consumers due to their limited rationality, which should be shown in textual, visual and other aspects of their perception of the CPE services offered by the educational institutions.To operationalize the theoretical ideas there has been developed a methodical approach to creating “a DNA molecule” of CPE services including the order of designing its elements. The fragment of “a DNA molecule” of educational services of CPE designed on the example of the educational program “Development and operation of oil and gas fields” by the Center of CPE of the branch of Ukhta state technical university in Usinsk with using Microsoft Excel; 3ds Max ® is presented. It was recommended to further researches of developing the communication strategy of the institutions realizing CPE services as a part of the marketing strategy of creating the image of CPE services.
Infinity and the Problem of Evil
Authors: Leslie John
Published: June 2019

God seemingly had a duty to create minds each of infinite worth through possessing God-like knowledge. People might object that God’s own infinite worth was all that was needed, or that no mind that God created could have truly infinite worth; however, such objections fail. Yet this does not generate an unsolvable Problem of Evil. We could exist inside an infinite mind that was one among endlessly many, perhaps all created by Platonic Necessity. “God” might be our name for this Necessity, or for the infinite mind inside which we existed, or for an infinite ocean of infinite minds.
Personalistic Theism, Divine Embodiment, and a Problem of Evil
Authors: Meister Chad
Published: June 2019

One version of the problem of evil concludes that personalistic forms of theism should be rejected since the acts that one would expect a God with person-like qualities to perform, notably acts that would prevent egregious evils, do not occur. Given the evils that exist in the world, it is argued, if God exists as a person or like a person, God’s record of action is akin to that of a negligent parent. One way of responding to this “argument from neglect” is to maintain that there is a good reason for the apparent neglect—namely, that God could not intervene even once with respect to suffering (the “not-even-once principle”) without thereby incurring the responsibility of doing so on every occasion, which would be deleterious. So God never responds to evil. It is argued in this paper that a profoundly integrated, personalistic model of God and the God-world relation—one that is reflected in a soul-body analogy—provides a way of addressing the argument from neglect without affirming the not-even-once principle.