bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effects of Vascular Cognitive Impairment on the Thickness of the Granular Cell Layer of the Dentate Gyrus within the Hippocampus in a Mouse Model
Authors: Radhakrishnan Akshaya , Jadavji Nafisa
Published: April 2019

Vascular Cognitive Impairment (VCI) is a form of dementia, most prevalent after Alzheimer’s Disease. However, VCI remains the second leading cause for dementia because it restricts blood flow to the brain and there are currently no treatments. There has been a positive correlation between VCI and hippocampal atrophy reported. Diet such as deficiencies in folic acid, is a modifiable risk factor for neurodegeneration. In the present study, a mouse model of VCI was combined with a deficiency in folic acid to assess hippocampal morphology. Animals were split into 4 experimental groups where they were placed into a control diet (CD) or folic acid deficient diet (FADD), and later these animals either had microcoils implanted around their common carotid arteries to model VCI or a sham, control surgery.  For hippocampal morphological analysis, the thickness of the granular cell layer of the dentate gyrus within the hippocampus was measured. It was hypothesized that a mouse model of VCI with microcoil treatment and reduced levels of folic acid would reduce blood flow, and increase cell death resulting in a reduced thickness of the granular cell layer within the dentate gyrus of the hippocampus. Our results show that thickness had an increasing trend in the in the FADD microcoil group. These data suggest that there may be an additional factor coming into play such as compensation by neural stem cells that needs to be further researched.
The Role of IFT140 in Osteogenesis of Adult Mice Long Bone
Authors: Tao Dike , Xue Hui , Zhang Chenyang , Li Gongchen , Sun Yao
Published: April 2019

Primary cilia have a pivotal role in bone development and the dysfunctions of primary cilia cause skeletal ciliopathies. Intraflagellar transport (IFT) proteins are conserved mediators of cilium signaling. IFT sub-complex A is known to regulate retrograde IFT in the cilium. As a core protein of IFT complex A, IFT140 has been shown to have a relationship with serious skeletal ciliopathies caused in humans. However, the effects and mechanisms of IFT140 in bone formation have not been systematically disclosed. To further investigate the potential role of IFT140 in osteogenesis, we established a mouse model by conditional deletion of IFT140 in pre-osteoblasts. The adult knock-out mice exhibited dwarf phenotypes, such as short bone length, less bone mass, and decreased bone mineral apposition rate. In addition, by IFT140 deletion, the expressions of several osteoblastic markers were decreased and loss of bone became severe with aging. These results suggest that cilia gene Ift140 is essential in bone development.
Time to Turn Up the Volume
Authors: Van der Linde Nadia
Published: April 2019

I remember my first self-organised donor panel well. It was at the Global Social Change Philanthropy Conference in Washington, DC in 2013. I had just started work as the first coordinator of the Red Umbrella Fund—the newly established fund for and by sex workers. I organised a session that would clarify the distinction between sex work and human trafficking and emphasise the need to fund sex worker organising. We had a strong panel: an awesome sex worker activist, a knowledgeable academic, a passionate service provider, and a committed funder. I was, however, in for a rude awakening: even though the line-up was great, the audience was scarce. I thought to myself, if we can’t even get funders to show up and learn about sex workers’ rights, how will we ever meet the needs of sex worker organisations fighting for their basic human rights?
Sex Worker Resistance in the Neoliberal Creative City: An auto/ethnography
Authors: Tigchelaar Alex
Published: April 2019

Sex workers are subjects of intrigue in urban and creative economies. Tours of active, deteriorating, or defunct red-light districts draw thousands of tourists every year in multiple municipalities around the world. When cities celebrate significant anniversaries in their histories, local sex worker narratives are often included in arts-based public offerings. When sex workers take up urban space in their day-to-day lives, however, they are criminalised. Urban developers often view sex workers as existing serviceably only as legend. A history of sex work will add allure to an up-and-coming neighbourhood, lending purpose to its reformation into a more appropriately productive space, but the material presence of sex workers in these neighbourhoods is seen as a threat to community wellbeing and property values. This paper considers how sex workers, continuously displaced from environments they have carved out as workspaces, may use the arts to draw attention to these ongoing contradictions. It investigates how sex workers may make visible the idiosyncratic state of providing vitality to a city’s history while simultaneously being excluded from its living present. Most critically, it suggests ways in which sex workers may encourage those involved as producers and consumers of neoliberal urban revitalisation projects to connect these often fatal paradoxes to the laws that criminalise their labour.
The Philippine Sex Workers Collective: Struggling to be heard, not saved
Authors: Parmanand Sharmila
Published: April 2019

The Philippine Sex Workers Collective is an organisation of current and former sex workers who reject the criminalisation of sex work and the dominant portrayal of sex workers as victims. Based on my interviews with leaders of the Collective and fifty other sex workers in Metro Manila, I argue in this paper that a range of contextual constraints limits the ability of Filipino sex workers to effectively organise and lobby for their rights. For example, the Collective cannot legally register because of the criminalisation of sex work, and this impacts their ability to access funding and recruit members. The structural configuration of the Philippines’ Inter-Agency Council Against Trafficking incentivises civil society organisations to adhere to a unified position on sex work as violence against women. The stigma against sex work in a predominantly Catholic country is another constraint. Recently, President Rodrigo Duterte’s war on drugs has been weaponised by some members of the police to harass sex workers. Finally, I reflect on strategies the Collective could adopt to navigate the limited space they have for representation, such as crucial partnerships, outreach work, and legal remedies.
Butterfly: Resisting the harms of anti-trafficking policies and fostering peer-based organising in Canada
Authors: Lam Elene , Lepp Annalee
Published: April 2019

Drawing on knowledge gleaned from over four years of community organising and from the ongoing compilation of the experiences of Asian and migrant sex workers in Canada, this article presents a case study of the work of Butterfly, a migrant sex worker-led and sex worker-focused organisation. It explores how Butterfly, through various mediums, has sought to challenge the discourses, laws, and policies that negatively impact Asian and migrant sex workers. It also highlights how the organisation, through its peer-based model and activities and its radical centring of the voices and experiences of Asian and migrant sex workers, is able to more effectively address their everyday realities and struggles. In this way, Butterfly offers a grassroots alternative to the often detrimental prohibitionist and anti-trafficking interventions undertaken by governments, law enforcement, and social service organisations.
Unacceptable Forms of Work in the Thai Sex and Entertainment Industry
Authors: Villar Leo Bernardo
Published: April 2019

This article examines the working conditions in sex and entertainment work in Thailand using the Unacceptable Forms of Work (UFW) Framework. Criminalisation of sex work and insufficient oversight of labour conditions increase the vulnerability of sex workers to police harassment; prevent sex workers from accessing legal and social protections; and contribute to the decent work deficit in the sector. Protecting the human rights of sex workers and ensuring decent work in the Thai sex and entertainment industry necessarily involves the decriminalisation of sex work; amending labour and social protection laws, policies, and systems to be inclusive of sex workers; and ensuring implementation. Throughout the process of policy change, the involvement of sex workers, their employers, and civil society organisations is crucial.
Chemically Modified Hydroxyapatite Nanocrystals by Temperature-Responsive Poly(N-isopropylacrylamide) via Surface Initiated Radical Polymerization
Authors: THUAN DOAN VAN , QUANG HIEU-VU , MINH BUI LE , THINH PHAM VAN , ISLAM MD. RAFIQUL , THANH HO VAN THI , NGUYEN DUY TRINH
Published: April 2019

This article reports on application of surface-initiated thiol-lactam initiated radical polymerization (TLIRP) method to modify hydroxyapatite nanocrystals (HAP) with thermoresponsive poly(N-isopropylacrylamide) (PNIPAm) brushes through grafting from strategy. Initially, 3-mercaptopropyl trimethoxysilane possessing thiol groups was functionalized with the -OH species on the surface of hydroxyapatite through ligand-exchanging response to introduce thiol species on hydroxyapatite (hydroxyapatite-thiol). Subsequently, attaching polymerization of N-isopropylacrylamide from HAP-SH surface was accomplished in the attendance of butyrolactam to produce PNIPAAmg-HAP. Thermogravimetric analysis, Fourier transform infrared, X-ray photoelectron spectroscopy and their thermal phase transition behaviour were employed to confirm the grafting and to characterize the nanoparticle structure.
Preparation of Amphoteric Ion Exchanger by Chemical Treatment of Scrap Tires
Authors: MALLAH ABDULRAHMAN
Published: April 2019

An amphoteric ion exchanger containing acidic and basic groups is prepared by chemical treatment of scrap tires by reaction with Sulphuric acid then the sulphonated sample aminated by ethylenediamine at different conditions in order to choose the best product within the thermal range of 120-170 ºC. The best conditions to obtain an amphoteric ion exchanger were at 150 ºC, for a period of 12 h, and mass ratio 1:1 of sulphonated sample to ethylenediamine. The maximum acidic and basic capacities were found as 2.40 and 2.55 meq g-1 of the selected ion exchanger respectively, wet and dry thermal stability process of the selected exchanger were also investigated.
Synthesis, Anti-inflammatory, Analgesic and Antipyretic Activity of Novel 1,3,5-Trisubstituted Pyrazole Derivatives
Authors: PADMINI THATAVARTHI , KAMAL BIGALA RAJ
Published: April 2019

A novel series of 1,3,5-trisubstituted pyrazole derivatives were synthesized by the cycloaddition reaction between the electron rich N-substituted aryl hydrazones and nitro-olefins. Different N-substituted aryl hydrazones (1a-j) on reacting with 4-methyl-β-nitrostyrene (2) in ethylene glycol or trifluoroethanol-trifluoro acetic acid mixture (for acid stable hydrazones) at 120 ºC, yielded various 1,3,5-trisubstituted pyrazoles (3a-j). The final products were characterized by spectral analysis using Mass, NMR and IR spectroscopy. All the products were assessed for their anti-inflammatory, analgesic and antipyretic activities on Swiss albino rats. All the compounds (3a-j) exhibited noteworthy defence against inflammation, nociception and hyperthermia. Compounds (3e and 3h) disclosed better antiinflammatory, analgesic and antipyretic activities while compound 3c had highest anti-inflammatory activity compared to the standard nimesulide.
Effect of Natural Drying Methods on Flavour Profile of Camphor Rich Ocimum americanum L. from North India
Authors: BISHT M. , RANA L. , TEWARI G. , PANDE C. , BHATT S.
Published: April 2019

In the present study, fresh aerial parts of Ocimum americanum L. were collected from Ramnagar, India and sun and shade drying was applied until constant weights. The fresh and dried plant materials were hydrodistilled by Clevenger apparatus and the extracted oils were analyzed by GC and GC/MS. One-way ANOVA and correlation were performed to evaluate the difference and correlation between drying treatments using SPSS 16.0. The major compounds of the fresh oil were camphor (33.41 %), maillol (11.96 %), β-selinene (8.34 %), α-selinene (6.92 %), β-gurjunene (5.43 %) and (E)-caryophyllene (5.07 %). In the dried samples, significant increase (p < 0.05) in the percentage of camphor and maillol was observed while the percentage of (E)-cayophyllene, β-gurjunene, β-selinene and α-selinene significantly (p < 0.05) decreased during drying process. Drying caused loss of fourteen constituents with appearance of four compounds. The oil yield was the highest under sun drying condition.
Kinetic, Equilibrium and Thermodynamic Studies on Removal of Cu(II) and Pb(II) by Activated Carbon Prepared from Macro-Algae (Kappaphycus alvarezii)
Authors: SATHASIVAM K.V. , FULORIA N.K. , FULORIA S. , DARSHENEE P.J. , XAVIER R. , MARIMUTHU K. , SUNDRAM K.M.
Published: April 2019

Present study was intended to explore the biosorption of Cu(II) and Pb(II) ions in aqueous solution using activated carbon biosynthesized from macro-algae Kappaphycus alvarezii under different experimental parameters. Activated carbon was produced via zinc chloride chemical activation method. The effect of parameters such as pH, temperature over biosorption, amount of adsorbents, initial Cu(II) and Pb(II) aqueous concentration, and contact time were studies. The pH 4.0 for adsorption of Cu(II) and Pb(II), and metal ions uptake contact time of 60 min were considered as optimum. Equilibrium data of biosorption were analyzed by models of Langmuir and Freundlich isotherm at different initial Cu(II) and Pb(II) aqueous solutions concentration. Fruendlich adsorption isotherm model fitted well into biosorption data with a regression value of 0.9986. Thermodynamic parameters such as change in change of enthalpy (ΔHº), change of entropy (ΔSº) and Gibbs free energy (ΔGº) were also determined.
Rapid Magnetic Solid-Phase Extraction Based on Graphene Oxide/Magnetite Nanoparticles for the Determination of Non-Steroidal Anti-Inflammatory Drugs and Bisphenol-A in Tap Water
Authors: ABDULLAH U.A.A. UNGKU , HANAPI N.S. MOHAMAD , IBRAHIM W.N.W. , AZHAR S. SAIFUL , ISHAK N.S. , HAMID R.D.
Published: April 2019

A simple and rapid magnetic solid-phase extraction based on reduced graphene oxide/ferroferic oxide (rGO/Fe3O4) coupled with high performance liquid chromatography-diode array detector (HPLC-DAD), was proposed for the determination of naproxen and diclofenac sodium of non-steroidal anti-inflammatory drugs (NSAIDs) and bisphenol-A residue in tap water sample. Fe3O4 was assembled with graphene oxide by facile method. Several important parameters, such as extraction time, desorption time and desorption solvent were studied and optimized. Optimal conditions were then used for the extraction of NSAIDs and bisphenol-A from real samples, prior to HPLC-DAD analysis using C18 column. The proposed method provides good linearity in the range of 1.0-5.0 mg L-1 (R2 naproxene = 0.9983, R2 diclofenac = 0.9960) for NSAIDs and R2 = 0.9919 for bisphenol-A; limit of detection of 0.031 mg L-1 and 0.023 mg L-1 for naproxen and diclofenac, respectively and 0.1785 mg L-1 for bisphenol-A; limit of quantification for naproxen and diclofenac were 0.102 and 0.076 mg L-1, respectively and 0.5949 mg L-1 for bisphenol-A; relative recoveries between 66.21 and 105.60 % for diclofenac and naproxen, respectively and 72.74 % for bisphenol-A; and acceptable reproducibility relative standard deviation (RSD, n = 3) of 6.79 and 11.32 % for diclofenac and naproxen, respectively and 0.93 % for bisphenol-A. The method was successfully applied to tap water sample and the results indicates that small residue of bisphenol-A is present the sample while no traces of NSAIDs was detected.
Degradation of Anionic Dye (Acid Orange II) by Bentonite Supported Nano-Zero Valent Iron
Authors: ZARIME N.A. , YAACOB W.Z. WAN , JAMIL H.
Published: April 2019

The nano-zero valent iron (nZVI) has been reported as an excellent material to decolourize the anionic dyes. Aggregation of nZVI tends to reduce its reactivity. Due to this reason, modifications of nZVI were applied by using bentonite. Bentonite supported nano-zero valent irons (B-nZVI) was synthesized by using reduction method of ferrous ions and sodium borohydride in presence of bentonite. The objective of this study was to evaluate the performance of composite nanoscale zero-valent iron (nZVI) in decolorized of acid orange II from aqueous solutions. All the three adsorbent materials (nZVI, B-nZVI and bentonite) were characterized by physical, chemical, mineralogical and morphological properties such as Brunnaer-Emmett-Teller (BET) surface area, X-ray photoelectron spectroscopy with auger electron spectroscopy (XPS-AES), field emission scanning electron microscopy (FESEM) and X-ray diffraction (XRD). The batch adsorption tests for all adsorbent materials have been conducted to determine the effectiveness of both materials in dye removal. The five effects have been analyzed in Batch test among others concentration, dose, pH, kinetic and temperature. The study found in all effects, BnZVI (qe opt = 8.9286 mg/g) showed the higher adsorption capacity followed by nZVI (qe opt = 8.1224 mg/g) and bentonite (qe opt = 5.8469 mg/g). The effectiveness of B-nZVI was due to the dispersion of nZVI particles bentonite particles, consequently provided more sites for adsorption. This study discovered that B-nZVI has a high potential to be a low-cost adsorbent for decolorized anionic dye from synthetic dye wastewater.
Synthesis, Characterization and Anticonvulsant Potential of 2,5-Disubstituted 1,3,4-Oxadiazole Analogues
Authors: KUMAR RAJNISH , ABDULLAH MOHD. MUSTAQEEM
Published: April 2019

A new series of compounds in which benzimidazole, oxadiazole and quinoline were incorporated, was synthesized and investigated for their anticonvulsant activity. Some of the newly synthesized compounds have shown good anticonvulsant activity. Significant anticonvulsant potency of the prepared derivatives has been evaluated by minimal electroshock and subcutaneous pentylenetetrazole animal model methods. The structure of synthesized compounds indicated that the introduction of strong electron donating groups like methoxy, amino and hydroxyl group and weak electron withdrawing halogen at phenyl ring attached to 1,3,4-oxadiazole moiety causes improvement in anticonvulsant activity. Locomotor behaviour was evaluated by actophotometer and toxicology study was also performed to evaluate their significance as required anticonvulsant compounds.
A indexação na base de dados Scopus
Authors: Almeida Marcio
Published: April 2019

"No mês de março, recebemos, com muita honra, a grata informação de que a nossa querida Revista Clínica de Ortodontia Dental Press (RCODP) passou no rigoroso processo de indexação na tão almejada base de dados Scopus. Na verdade, ser indexada na base de dados Scopus é uma conquista deveras importante para toda e qualquer revista no mundo, e alcançar esse — se assim pudermos chamar— “sucesso” traz consigo não apenas uma medida de satisfação para os Editores, mas também a comprovação da qualidade da revista para outros membros da comunidade científica..."
A Ortodontia e o periodonto: coisas que devemos saber
Authors: Janson Marcos
Published: April 2019

"Meus amigos, é frequente nos depararmos com casos clínicos, que irão iniciar a movimentação ortodôntica ou que já estão em andamento, que apresentam recessões gengivais. O que o ortodontista pode ou deve fazer quando encontra essa situação?.."
Espaçador para haste mandibular do APM IV
Authors: Bastos Marden
Published: April 2019

"O uso de propulsores mandibulares tem se tornado cada vez mais evidente. Entre os vários modelos, destaca-se o APM IV, desenvolvido pelo brilhante Dr. Carlos Martins Coelho Filho, construído com tubos telescópicos de 1,2 mm e fio de aço de 1,0 mm de diâmetro. Porém, uma das críticas feitas a esse aparelho é seu alto índice de quebras, sendo que um dos motivos disso acontecer é o deslocamento da haste mandibular para dentro do círculo feito no arco inferior para ancorá-la. Esse deslocamento pode provocar o travamento do aparelho durante o fechamento da boca, bem como levar a haste maxilar a tocar nos braquetes dos pré-molares, causando um efeito guilhotina, com fratura de braquetes e/ou do APM..."
MARPE – Quais os efeitos esperados?
Authors: Gurgel Júlio de Araújo
Published: April 2019

"Devido à diversidade de desenhos do MARPE (osseossuportados: apenas ancoragem esquelética; dento-osseossuportados: ancoragem esquelética e dentária, ancorados com dois mini-implantes ou com quatro mini-implantes), às variações nos sítios de instalação dos mini-implantes, à inserção bi ou monocortical dos mini-implantes, às diferentes faixas etárias avaliadas e aos diferentes protocolos de ativação utilizados nos estudos publicados na literatura, não há, atualmente, consenso em relação aos efeitos produzidos por essa mecanoterapia. Portanto, na atualidade, os resultados devem ser comparados com máxima atenção, considerando- se os fatores previamente descritos..."
Cirurgia ortognática para tratamento de má oclusão de Classe III: relato de caso clínico
Authors: Fernandes Bruno Viezzer , Peters Calisson Ildemar , Coelho Ulisses , Fernandes Tito Lúcio , Klüppel Leandro Eduardo
Published: April 2019

Introdução: a cirurgia ortognática é uma modalidade de tratamento voltada para a correção das deformidades dentofaciais que envolve uma equipe multidisciplinar, conduzida pela interação do cirurgião bucomaxilofacial com o ortodontista. O tratamento ortodôntico associado a técnicas cirúrgicas, como osteotomia sagital bilateral dos ramos mandibulares e osteotomia Le Fort I, trouxe grandes avanços para a correção das más oclusões esqueléticas com o objetivo de obter uma oclusão funcional, visando a saúde das estruturas orofaciais, harmonia facial e dentária, e estabilidade dos resultados. Objetivo: o presente trabalho exemplifica o tratamento ortodôntico-cirúrgico contemporâneo com o relato de um caso clínico de deformidade dentofacial Classe III. Relato de caso: paciente do sexo masculino, 23 anos de idade, portador de má oclusão Classe III esquelética com histórico de tratamento ortodôntico compensatório prévio, com indicação de tratamento ortodôntico- cirúrgico com a finalidade de aprimorar as funções mastigatória, respiratória e de fonação, aliada à melhora da estética facial e do sorriso. Resultados: após 16 meses de preparo ortodôntico, foi realizada cirurgia ortognática com avanço de maxila, recuo de mandíbula e mentoplastia de avanço. No controle pós-operatório de 6 meses, com o tratamento ortodôntico finalizado, apresentou resultados funcionais e estéticos favoráveis. Conclusões: a correta indicação do tratamento ortodôntico-cirúrgico representa um método eficaz para a correção das más oclusões esqueléticas, proporcionando resultados funcionais satisfatórios, com previsibilidade e estabilidade adequadas.
Tratamento compensatório das más oclusões do Padrão II deficiência mandibular: relato de caso
Authors: Piccoli Vicente Dias , Guedes Fabio Pinto , Rhoden Fernando Kleinübing , Cardoso Maurício de Almeida , Capelozza Filho Leopoldino
Published: April 2019

O presente artigo descreve, por meio de um caso clínico, o tratamento compensatório de uma má oclusão do Padrão II deficiência mandibular associada à relação oclusal de Classe II, divisão 1. A paciente foi submetida a um manejo ortopédico mandibular com aparelho Herbst, seguido de finalização com Ortodontia fixa. O tratamento, realizado em duas etapas subsequentes, proporcionou à paciente estética e função adequadas em um espaço de tempo relativamente curto, reforçando a importância de um criterioso diagnóstico para definição de metas terapêuticas individualizadas.
O impacto da intervenção ortodôntica no desenvolvimento da dentição e da oclusão
Authors: Romano Fábio Lourenço , Matsumoto Mírian Aiko Nakane
Published: April 2019

A intervenção ortodôntica na dentição mista contribui, de forma significativa, para diminuir a gravidade das más oclusões, permitindo um tratamento corretivo mais rápido e com menor complexidade. Em algumas situações, a intervenção apropriada pode solucionar de forma definitiva os problemas oclusais, evitando qualquer tipo de tratamento futuro. O objetivo do presente artigo foi relatar a intervenção ortodôntica realizada em uma criança com 7 anos de idade, que apresentava hipoplasia transversal da maxila e mordida aberta anterior dentária na dentição mista, sendo que nenhum tratamento ortodôntico corretivo foi necessário na dentição permanente. A hipoplasia transversal maxilar foi corrigida com expansão rápida da maxila (ERM), seguida de aparelho de contenção removível superior com grade palatina, para interceptação do hábito de interposição lingual. Após aproximadamente 12 meses de tratamento, os problemas oclusais foram corrigidos, e a paciente foi acompanhada até a dentição permanente. Pôde-se concluir com esse relato que a intervenção ortodôntica na dentição mista, quando realizada de forma adequada e criteriosa, pode reduzir os problemas ortodônticos futuros ou evitá- los, pois elimina interferências no crescimento e desenvolvimento dos dentes e ossos maxilares, viabilizando a obtenção de oclusão e estética facial satisfatórias.
The contribution of customized lessons with cultural content in the learning of EFL among undergraduates
Authors: Oviedo Gómez Hans Humberto , Álvarez Guayara Henry Alberto
Published: April 2019

This qualitative descriptive action research study explores the contribution of customized lessons with cultural content in the learning of English as a Foreign Language (EFL).. This study was conducted with a group of 17 undergraduates from the English Language Teaching (ELT) program at a state university in south-eastern Colombia. Data were collected via students’ artefacts (EFL lessons developed by the participants) with corresponding self-assessment, teachers’ field notes, and surveys on students’ perceptions. Findings suggest that designing customized lessons anchored in principles of second language acquisition results in more effective language learning. Additionally, using cultural content in the lessons makes communication more meaningful as undergraduates develop cultural knowledge and understanding. Finally, addressing learning styles and providing learning strategies in the lessons greatly contribute to EFL learning among undergraduates.
A comparative study of Mexican and Irish compliment responses
Authors: Flores-Salgado Elizabeth , Witten Michael T.
Published: April 2019

The purpose of the present study is to compare the compliment responses (CRs) provided by 60 native Mexican Spanish speakers and 60 Irish English native speakers. Using a discourse completion task, 1080 responses were analyzed based on Herbert’s (1989) and Nelson, El Bakary and Al-Batal’s (1993) taxonomy. Findings suggest the existence of cross-cultural similarities in Irish and Mexican CRs in the frequency of deﬂecting comments and the mechanisms that are used to redirect the praise force. Second, the two languages differ in important ways. In responding to compliments, Irish recipients are much more likely than Mexican speakers to use a single strategy when formulating CRs. The fndings further show that social factors (social distance, social power, gender, and the topic of the compliment) in both Mexican and Irish society seem to be crucial parameters in the formulation and acceptance or rejection of a compliment.
MENAKAR IDEALITAS LAPANGAN PUPUTAN SEBAGAI RUANG PUBLIK MASYARAKAT KOTA DENPASAR
Authors: Nugroho Wahyu Budi , Kamajaya Gede
Published: April 2019

This research discusses public space in Denpasar, Bali, focusing on Lapangan Puputan. Theoretically, public space has three functions, namely recreational, social interaction and political aspect. Using Habermas's theory on public space, this article found Lapangan Puputan fulfils three functions of public space. Yet, there is a lack of society's understanding on the function of public space, in which the space is functioned more for economic activity. They also refuse if Lapangan Puputan is used for political activity.
Analisa MRR, EWR, DOC terhadap Beberapa Material Elektroda pada Proses EDM Die Sinking
Authors: Londa Petrus
Published: April 2019

Electrical Discharge Machining (EDM) adalah non-conventional machining process. EDM dapat memotong semua jenis benda kerja yang bersifat penghantar listrik, terutama digunakan pada benda kerja yang sangat keras dan memiliki bentuk yang rumit, yang tidak dapat dipotong oleh mesin konvensional. Penelitian ini menggunakan metode Taguchi untuk menentukan variabel pemesinan yang secara signifikan mempengaruhi proses pemotongan pada beberapa material elektroda (tembaga, kuningan, alumunium) dan benda kerja dari bahan K460 (amutit S). Taguchi L25 Orthogonal standard arrays dan analysis of variance (ANOVA) dapat menentukan performa variabel pemotongan (PON, POFF, GAP, QDON, SERVO dan LT) dengan variabel yang diteliti adalah Electrode Wear Rate (EWR), Material Removal Rate (MRR) dan Diameter Overcut (DOC). Hasil dari penelitian ini ditampilkan dalam bentuk tabel-tabel dan grafik yang menunjukan variabel pemesinan yang signifikan mempengaruhi proses pemotongan sesuai dengan jenis material elektroda yang digunakan.
Karakterisasi Karbon Aktif dari Bulu Ayam untuk Aplikasi Penyimpan Gas Hidrogen (Hydrogen Storage)
Authors: Alhamidi Ali , Kustiningsih Indar , Poetra Irmansyah
Published: April 2019

Salah satu alternatif penyimpanan hidrogen adalah dengan metode adsorpsi menggunakan karbon aktif karena memiliki kemampuan adsorpsi yang yang besar berkaitan dengan luas permukaan dan ukuran porinya.Untuk meningkatkan daya adsorpsi dari adsorben dapat dilakukan dengan menjadikan sebanyak mungkin porinya yang termasuk kategori micropori sehingga sesuai dengan ukuran molekul hidrogen sebagai adsorbate. Dengan semakin besarnya prosentase mikropori yang dimiliki dibandingkan makropori dan mesoporinya, maka kemampuan adsorpsi dari adsorben tersebut diharapkan akan meningkat. Penelitian ini menggunakan material bulu ayam sebagai bahan baku pembuatan karbon aktif. Bulu ayam sebelumnya dikarbonisasi dahulu selama 60 menit pada suhu 4000C hingga terbentuk arang/karbon. Karbon kemudian diaktivasi secara kimia yaitu dengan cara mencampurkan karbon dengan KOH dengan perbandingan 1:2. Dalam penelitian ini karbon aktif dibentuk menjadi dua yaitu bentuk serbuk dan pellet. Pada karbon aktif pellet terjadi penambahan binder sebagai perekat. Setelah tahap pencampuran, karbon kemudian diaktivasi pada temperatur 4000C, 5000C, 6000C selama 60 menit. Hasil percobaan kemudian dikarakterisasi dengan pengujian SEM dan uji BET. Hasil pengujian BET menghasilkan luas permukaan pori tertinnggi dihasilkan oleh karbon aktif serbuk dengan nilai 3,257 m2/g dan 3,109 m2/g untuk karbon aktif pellet. Sedangkan hasil terendah didapat karbon aktif bentuk pellet sebesar 1,47 m2/g dan 0,796 untuk karbon aktif serbuk. Pada uji SEM terlihat perbedaan anatar karbon sebelum aktivasi dan sesudah aktivasi yaitu terlihat pori yang terbuka setelah karbon diaktivasi.
Penggunaan Styrofoam sebagai Material Bilah Turbin Angin
Authors: Ikaningsih Manty Aldilani , Rosihan War’an
Published: April 2019

Percobaan pembuatan bilah turbin angin dengan bahan kayu dan styrofoam dilakukan dengan tujuan agar pada kecepatan tertentu bilah dapat rusak. Kerusakan ini dipusatkan pada bagian styrofoam yang memiliki tingkat ketahanan pembebanan di bawah kayu. Kerusakan bilah tersebut nantinya akan melindungi generator agar tidak mengalami overspeed. Pada penelitian ini, desain bilah turbin angin yang digunakan berasal dari lembaga penelitian Lentera Angin Nusantara. Bilah turbin angin yang dibuat adalah tipe taperless, dimana ukuran bilah sama dari pangkal hingga ujung. Modifikasi bilah turbin angin dilakukan berdasarkan hasil simulasi performa bilah turbin angin dengan menggunakan perangkat lunak QBlade. Pada hasil simulasi ditunjukkan bahwa sumbangsih terbesar harga torsi total berasal dari torsi elemental dari bagian bilah pada posisi 50% - 100% panjang bilah. Berdasarkan hasil simulasi performa bilah turbin angin tersebut, maka bilah turbin angin yang dibuat dari bahan dasar kayu dimodifikasi dari bagian tengah hingga bagian ujung belakang dengan menggunakan styrofoam. Harapannya modifikasi tersebut akan mencegah overspeed pada generator dan memusatkan kerusakan di bagian bilah yang terbuat dari styrofoam akibat gaya dorong saat kecepatan angin cukup tinggi. Jika uji lapangan berhasil, maka pemusatan letak kegagalan bilah akan meminimalisir kerusakan (patahnya) bilah di bagian yang tidak terprediksi.
THE IMPORTANCE OF AFFECT IN LANGUAGE LEARNING
Authors: Arnold Jane
Published: April 2019

As language teachers, we have to pay attention to many things in our work but cognitive aspects of foreign or second language learning cannot provide all the information we need. If we also give attention to the affective domain, this can make our teaching more effective. In this article we will be considering some of the affective factors and exploring how they influence the process of language learning. Special emphasis will be placed on implications for teachers in the classroom.
Patient reported outcomes and neuropsychological testing in patients with chronic non-cancer pain in long-term opioid therapy: a pilot study
Authors: Diasso Pernille D. K. , Sjøgren Per , Højsted Jette , Nielsen Susanne D. , Main Katharina M. , Kurita Geana P.
Published: April 2019

Background and aims

Opioid consumption has increased dramatically in patients with chronic non-cancer pain (CNCP), but long-term consequences are still unclear. The aim of this study is to investigate the effects of long-term opioid treatment on pain, cognition, mood, sleep and quality of life in CNCP patients.

Methods

In this cross-sectional pilot study, two groups of patients with CNCP treated in a multidisciplinary pain center were selected: (1) opioid group: ≥30 mg morphine equivalent/day for >4 weeks, and (2) control group: no opioid consumption for >4 weeks. Socio-demographic data, alcohol consumption, smoking habits and body mass index (BMI) were registered and pain (brief pain inventory), mood (Hospital Anxiety and Depression Scale), sleep (Pittsburgh Sleep Quality Index) and quality of life (RAND 36-Item Health Survey) were assessed. Continuous Reaction Time and the Digit Span Test were used to evaluate cognitive function. Data was analyzed with a Fisher’s exact test and Wilcoxon two-sample test.

Results

Forty-two patients with CNCP were included (21 in each group). No differences regarding socio-demographics, smoking/alcohol habits and duration, type, or intensity of pain were found. More patients in the opioid group had significantly higher BMI (62% above BMI 25 vs. 33.3%, p = 0.042). Consequently, the subsequent data analyses were controlled for BMI. The two groups did not differ in pain, cognition, anxiety, depression, sleep or quality of life but both showed lower values than the normal standards. Further, the opioid group presented a tendency to lower ratings regarding pain and social function and performed below the normal cut off in the continuous reaction time.

Conclusions

No significant differences between the two groups were found regarding any of the above-mentioned variables. Interestingly, the patients assessed, regardless of taking opioids or not, could be classified with moderate pain intensity, anxiety and low quality of sleep and life compared to norm standards.

Implications

The findings of this pilot study suggested that long-term opioid treatment may influence pain and quality of life among CNCP patients. A larger cohort is needed to verify these findings.
Difference in the ascending reticular activating system injury between mild traumatic brain injury and cerebral concussion
Authors: Jang Sung Ho , Kim Seong Ho , Lee Han Do
Published: April 2019

Introduction

We investigated differences in the ascending reticular activating system (ARAS) injuries between patients with mild traumatic brain injury (mTBI) and cerebral concussion by using diffusion tensor tractography (DTT).

Methods

Thirty-one patients with mTBI, 29 patients with concussion, and 30 control subjects were recruited. We used DTT to reconstruct the lower ventral and dorsal ARAS, and the upper ARAS. The fractional anisotropy (FA) value and the fiber number (FN) of the lower ventral and dorsal ARAS, and the upper ARAS were determined.

Results

Significant differences were observed in the FA values of the lower ventral and dorsal ARAS on both sides between the mTBI and control groups and between the concussion and control groups (p < 0.05). The FN value was significantly different in the lower ventral ARAS on both sides between the concussion and control groups and between the mTBI and concussion groups (p < 0.05).

Conclusion

Both the mTBI and concussion patients suffered injuries in the lower ventral and dorsal ARAS, with the concussion patients exhibiting more severe injury in the ventral ARAS than that in the mTBI patients. These results suggest that the terms mTBI and concussion should be used differentially, even though they have used interchangeably for a long time.
Battle Rope Conditioning
Authors: Langford Emily L. , Wilhoite Sydni , Collum Connor , Weekley Hunter , Cook Jordan , Adams Kara , Snarr Ronald L.
Published: April 2019

This column provides an analysis of the proper technique for battle rope conditioning. Specific musculature involvement, benefits of battle rope training, exercise technique, as well as advanced and beginning progressions are discussed. This dynamic movement is designed to improve cardiorespiratory endurance, muscular strength, endurance, and power. Specific variations for battle rope conditioning can provide various benefits to athletes such as enhancing sport-specific movements, increasing grip strength, and addressing unilateral deficits. Thus, the implementation of battle rope conditioning for an exercise regimen should be considered.
DNA methylation in thyroid cancer
Authors: Zafon Carles , Gil Joan , Pérez-González Beatriz , Jordà Mireia
Published: April 2019

In recent years, cancer genomics has provided new insights into genetic alterations and signaling pathways involved in thyroid cancer. However, the picture of the molecular landscape is not yet complete. DNA methylation, the most widely studied epigenetic mechanism, is altered in thyroid cancer. Recent technological advances have allowed the identification of novel differentially methylated regions, methylation signatures and potential biomarkers. However, despite recent progress in cataloging methylation alterations in thyroid cancer, many questions remain unanswered. The aim of this review is to comprehensively examine the current knowledge on DNA methylation in thyroid cancer and discuss its potential clinical applications. After providing a general overview of DNA methylation and its dysregulation in cancer, we carefully describe the aberrant methylation changes in thyroid cancer and relate them to methylation patterns, global hypomethylation and gene-specific alterations. We hope this review helps to accelerate the use of the diagnostic, prognostic and therapeutic potential of DNA methylation for the benefit of thyroid cancer patients.
Šventoji ir pasaulietinė muzika Šventajame Rašte
Authors: Miliūnaitė Miglė
Published: April 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba] Straipsnyje šventosios ir pasaulietinės muzikos santykio problema svarstoma analizuojant giedojimo ir instrumentinės muzikos ypatybes Šventojo Rašto tekste. Šios perskyros susidarymą bandoma aptikti Mircea Eliade’s šventybės ir pasaulietiškumo perskyros pagrindu interpretuojant muzikos charakteristiką Senajame Testamente bei jos transformaciją Naujajame Testamente. Straipsnyje siekiama parodyti, kad reguliaraus ritmo ir daugiabalsumo parametrai dominuoja pasaulietinėje muzikoje, o monofonija pasakojime atsiskleidžia kaip šventosios muzikos bruožas.
Neįvykęs pokalbis: Del Noce’ė ir Vattimo apie ateizmą, sekuliarizaciją ir nihilizmą
Authors: Markevičius Domantas
Published: April 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]

Straipsnyje siekiama suprobleminti Roberto Esposito pasiūlytą Augusto Del Noce’ės ir Gianni Vattimo požiūrių į sekuliarizaciją ir nihilizmą analizę ir pateikti alternatyvią jų santykio interpretaciją. Tuo tikslu lyginami Del Noce’ės ir Vattimo modernybės ir ateizmo apmąstymai ir jais paremtos skirtingos sekuliarizacijos bei nihilizmo fenomenų interpretacijos. Teigiama, kad Esposito neadekvačiai įvertina tarp Del Noce’ės ir Vattimo filosofijų kylantį prieštaravimą. Del Noce’ės moderniojo ateizmo interpretacija turėtų būti vertinama ne kaip „ištirpstanti“ Vattimo silpnajame mąstyme, o kaip svarbus šiuolaikinės italų filosofijos idėjinio pliuralumo tyrinėjant sekuliarizacijos ir nihilizmo fenomenus ženklas.
Nuevos hospederos alternativos de begomovirus asociados al cultivo de ají en el Valle del Cauca.
Authors: Vaca-Vaca Juan Carlos , Corredor-Saenz Viviana , Jara-Tejada Frenyiline , Betancourt-Andrade Dyanela , Lopez-Lopez Karina
Published: April 2019

Los begomovirus (virus de plantas de DNA de cadena sencilla) son la principal amenaza para los cultivos que crecen en áreas subtropicales y tropicales de todo el mundo. Hay muchos estudios que han demostrado que los begomovirus evolucionan por mecanismos de intercambio genético, que ocurren en hospedadores alternativos como las malezas. Las malezas están ampliamente distribuidas en todo el mundo y tienen una alta adaptabilidad ambiental. El objetivo de este trabajo fue identificar nuevos hospederos alternos de begomovirus en malezas asociadas con cultivos de aji que crecen en el Valle del Cauca. Malezas con y sin síntomas virales alrededor de cultivos de aji ubicados en los municipios de Zarzal, Vijes, Toro, Unión, Roldanillo y Guacarí fueron colectadas; Se realizó una identificación taxonómica en el Herbario de la Universidad Nacional de Colombia, Josep Cuatrecasas Arumí.La detección de begomovirus se realizó mediante PCR utilizando cebadores universales que amplifican 400 pb, correspondientes a un fragmento del gen AR1 (CP) del componente A. Se recolectaron 179 malezas y en 13 de ellas (Sida acuta, Malvastrum sp, Rivina humilis, Acalypha sp, Parthenium hysterophorus, Euphorbia hirta, Rhynchosia minima) se detectó la presencia de begomovirus. Para malezas como Sida acuta y Acalypha sp, este es el primer informe como hospedero alterno de begomovirus en Colombia, América Latina y el Caribe. Este resultado permite conocer nuevas familias como hospederas de begomovirus y también para confirmar la presencia de begomovirus en otras malezas donde se detectaron previamente en el Valle del Cauca. Existe una necesidad apremiante de obtener información adicional relacionada con la diversidad y la distribución de malezas como hospederos de begomovirus, con el fin de descubrir no solo el control del virus, sino también evitar la propagación del begomovirus de las malezas a los cultivos con interés económico.
Dakwah Majelis Rasulullah dan Kecintaan Jama’ah kepada Dakwah Islam
Authors: Ikrima Anisatul , Diningrat Karsidi , Rojudin Rojudin
Published: April 2019

This research discusses the Islamic proselytizing conducted by Majelis Rasulullah Tambun Cibitung Cikarang, the congregations love of the forum toward Islamic proselytizing, and the influence of Islamic proselytizing conducted by Majelis Rasulullah Tambun Cibitung Cikarang on the congregations of the forum’s love. The result showing the amount of X variable reach 46,4. After divided by the number of items obtained the number 4,64 and the amount of Y variable reach 47,36.  After divided by the number of items obtained the number 4,736. The both of this variable has very high qualification because at interval 4,20-5,00. The correlation coefficient is 1,0. The value of correlation coefficient in this research was at the interval 0,81-1.00 which expressed perfect correlation. The influence Majelis Rasulullah, has coefficient 1,0 with 40% level of influence, it can be concluded that there are still around 60% from other factor which also influence to follower’s love in Islamic proselytizing.

Penelitian ini mengungkapkan dakwah Islam yang dilakukan oleh Majelis Rasulullah Tambun Cibitung Cikarang, kecintaan jama’ah terhadap dakwah Islam, dan pengaruh dakwah Islam yang dilakukan Majelis Rasulullah Tambun Cibitung Cikarang terhadap kecintaan jama’ah. Metode Penelitian menggunakan analisis kuantitatif. Hasil penelitian menunjukkan jumlah variabel X mencapai 46,4. Setelah dibagi jumlah item diperoleh angka 4,64 dan jumlah Variabel Y mencapai 47,36. Setelah dibagi oleh jumlah item diperoleh angka 4,736. Kedua variabel ini memiliki kualifikasi sangat tinggi karena berada pada interval 4,20–5,00. Koefisien kolerasi sebesar 1,0. Nilai koefisien korelasi pada penelitian ini berada pada interval 0,81-1,00 yang dinyatakan korelasi sempurna. Pengaruh Majelis Rasulullah, koefisiennya 1,0 dengan kadar pengaruhnya 40% hal tersebut dapat disimpulkan bahwa masih ada sekitar 60% dari faktor lain yang turut mempengaruhi terhadap kecintaan jama’ahnya dalam dakwah Islam.
Debt and Bondage Records of the Joseph-Volokolamsk Monastery as a Source for Studying Monastic Borrowers in the Middle of the Time of Troubles (1606–1609)
Authors: Tseluykina Evgeniya
Published: April 2019

Introduction. To study the peasantry of the 16th – the early 17th century in Russia we need information from all the territories of the state. There are unique documents in the archives of the Joseph-Volokolamsk monastery for the central part of the Russian state, which allow us to investigate the issue of monastic enslavement. This issue has not been studied enough regarding the early 17th century.

Methods and materials. Such a source as a borrowed monastic bondage is poorly studied in historiography. In this regard the aim of the article is to study the position of monastery borrowers according to the form of debt records of the early 17th century. There are objectives: to identify the elements of the form of bondage records that reflect the position of the borrowers; to consider changes in the position of borrowers based on the debt book form evolution. The article uses the methods of formal and comparative analysis with respect to records in debt books of 7115 (1606/07), 7116 (1607/08), the bondage book of 1609, and borrowed bondages of 1609.

Analysis. The records of money issuance debt books of 1606/07 and 1607/08 were compared with the information from the debt book of 1532-1534. The author traced the evolution of debt charging book design elements based on the sources of 1606/07 and 1607/08. The paper analyzes borrowed bondages of besieged people on borrowed monastery bread in 1609, along with the bondage book of 1609. These results were compared with the bread bondages of the Spaso-Prilutsky monastery.

Results. The form of debt records has been well developed by the early 17th century. According to money issuance and charge records, a borrower was protected from lender’s abuses. However, bread bondages most objectively reflect the position of a debtor, who was in danger of enslavement because of vague wording in bondages.