bluuebunny/crossref_metadata_2025 huggingface dataset:
Desafiando al “feminismo”. Voces de La Libertad Avanza en el contexto argentino actual
Authors: País Andrade Marcela , Zani Alejandra , Kaplan Yanina , Russo Sierra Georgina
Published: December 2024

Este ensayo examina las narrativas sobre el feminismo en el contexto de la presidencia de Javier Milei en Argentina, centrando el análisis en dos figuras clave del partido político La Libertad Avanza: Victoria Eugenia Villarruel y Lilia Adela Bolukalo Lemoine. Nuestro corpus de estudio incluye dos entrevistas realizadas en el último año (difundidas a través de plataformas de streaming) que ponemos en diálogo con estudios académicos sobre el tema. Nos proponemos explorar cómo las narrativas de estas mujeres interpelan y desafían las nociones de feminismo y las políticas de género en Argentina en las últimas décadas. Identificamos cinco palabras clave: educación sexual, violencia de género, feminismo, identidad de género y aborto, que estructuran tres ejes analíticos: a) el feminismo como construcción ideológica, b) la noción de meritocracia y autonomía sobre el propio cuerpo, y c) el papel del Estado en estos procesos.A lo largo del ensayo, observamos cómo Villarruel y Lemoine articulan una compleja red de temas relacionados con el mérito, la meritocracia y el rol de la mujer en la sociedad contemporánea, entrelazando estas discusiones con la crítica al “feminismo”, la identidad colectiva y la igualdad de género. Este análisis nos permite identificar continuidades y rupturas con lo político de la sexualidad en los procesos de subjetivación a través de las narrativas de estas mujeres liberal-libertarias. Aunque estas perspectivas no son novedosas en cuanto a las discusiones sobre sexualidad, nos dejan con preguntas incómodas que aún no sabemos responder.ARK: https://id.caicyt.gov.ar/ark:/s18535925/rkqnriyri
Una nueva regulación de les pobres y sus hijes. El discurso autoritario francés post COVID
Authors: Bazile Katia
Published: December 2024

Este artículo examina los discursos autoritarios emergentes en Francia durante el periodo post-COVID (2020-2024) y la reestructuración política de una nueva derecha radical e intransigente con les pobres y las minorías tras la crisis sanitaria y social. Se demostrará el impacto de estos discursos autoritarios y paternalistas en la precarización, el control y la criminalización de padres, madres e hijes, especialmente en contextos de pobreza y marginación. El artículo también analiza el impacto de estos discursos autoritarios para la juventud según el género. A través de un enfoque metodológico claramente definido, se analizan estos discursos de banalización de los discursos de extrema derecha, de tolerancia cero, de odio, de racismo y sexismo dirigidos especialmente hacia la juventud pobre y proveniente de pueblos descolonizados, en el contexto de las últimas elecciones, así como la configuración ideológica de las poblaciones afectadas. El sujeto de estudio es Francia, pero se vinculará con discursos y sobresaltos autoritarios de manera más amplia, para demostrar su aplicabilidad a lo largo de la historia y del desmantelamiento de los derechos sociales a través un sistema social cada vez más mezclado con el sistema penal de control y castigo de los pobres con un enfoque particular en la criminalización por el sistema welfare de las malas madres pobres y sus hijes. Finalmente, se aborda la polarización ideológica entre juventudes y género, ofreciendo un análisis completo y estructurado de los fenómenos estudiados.ARK:  https://id.caicyt.gov.ar/ark:/s18535925/7nbpvbbav
Humillación y desinhibición. Para una crítica del fascismo contemporáneo
Authors: Cerruti Pedro
Published: December 2024

Este ensayo examina las llamadas “nuevas derechas” a la luz de una reconsideración de la relación entre política, afectividad y comportamientos multitudinarios, y de una reconsideración del fascismo como forma de subjetivación. Para ello, en primer lugar, se recorren a través de una lectura crítica, las hipótesis centrales de la psicología de las masas, y los diagnósticos de George Simmel relativos a la sobreestimulación, el intelectualismo y la reserva propias de la vida urbana, y son puestas en relación con las nociones de “shock” y de la pérdida de la experiencia de Walter Benjamin, a través de la interpretación de Susan Buck-Morss, y su forma de reconsiderar a partir de ello la estetización de la política. En segundo lugar, se propone una lectura de la teoría de la propaganda formulada por Harold Lasswell, y su forma de comprender la transformación de la guerra en una confrontación psicológica, movilizando emociones, tales como el odio y la esperanza, como técnicas de desinhibición. Finalmente, se ofrece una interpretación de la condición moderna de la subjetividad a partir de la figura de la humillación, en la que se recupera la perspectiva de Elias Canetti y las lecturas de Sloterdijk sobre el problema de la masa como diferencia indiferenciada.ARK: https://id.caicyt.gov.ar/ark:/s18535925/s9xzp380k
Gambaran Pendidikan Karakter Disiplin di Era Digital Pada Siswa Kelas V di SDN 02 Laladon Bogor
Authors: Nabilah Farhah  , Fitira Rosmi  , Dace
Published: December 2024

This study aims to describe the character education of discipline in grade V students of SDN 02 Laladon Bogor in the digital era. The digital era has a significant impact on the development of character education, especially discipline. This study uses a qualitative method with data collection techniques through observation, interviews, and documentation studies. The results of the study indicate that character education of discipline in grade V students of SDN 02 Laladon Bogor faces challenges and opportunities in the digital era. Factors such as the use of technology, parenting patterns, and school environment influence the formation of students' disciplined character. These findings provide insight into the efforts that need to be made in improving character education of discipline in the digital era, including the development of relevant learning methods and the active role of parents in supporting character education at home. This study is expected to contribute to increasing understanding and awareness of the importance of character education of discipline in changing times. The practical implications of this study can be used as a guideline for educators, parents, and related parties in designing effective strategies to develop discipline in grade V students in the digital era.
Analisis Yuridis terhadap Kendala dalam Implementasi Pelaksanaan Kerja Sama Daerah di Kabupaten Sumenep
Authors: Mohamad Faishal Agil  , Ansori Ansori
Published: December 2024

Regional cooperation agreements are not something new, these regional cooperation agreements have a positive impact in improving people's welfare which makes this cooperation based on considerations of efficiency and effectiveness of public services that are mutually beneficial. In practice, there are problems that often arise in regional cooperation agreements. In this research, we want to examine in more depth the flow of implementing regional cooperation agreements and also want to examine what factors cause the failure or non-performance of a regional cooperation agreement with the Sumenep Regency Government. The results of this research are that the stages in regional cooperation agreements are regulated in Minister of Home Affairs Regulation No. 22 of 2020 article 6. And the problems that often arise are 1) The cooperation agreement that will be carried out is not accompanied by a draft of a mutual agreement between the regent and the leadership of the party that will collaborate. 2) Most of the articles on rights and obligations as well as financing have not found common ground so that the draft text of the cooperation agreement that has been discussed has not yet been signed. 3) The draft cooperation agreement that was prepared several times is not in accordance with the Minister of Home Affairs Regulation on Procedures for Regional Cooperation with Other Regions and Regional Cooperation with Third Parties.
Pencegahan dan Penanganan Tindak Kekerasan Terhadap Anak oleh Dinas Pemberdayaan Perempuan, Perlindungan Anak, Pengendalian Penduduk dan Keluarga Berencana (DP3KB) di Kabupaten Bintan
Authors: Dini Oktavia Putri  , Wanda Hafisya  , Mahesa Arya Pratama
Published: December 2024

Child abuse in Indonesia, particularly in Bintan, shows a concerning upward trend. This study aims to analyze the efforts of the Women's Empowerment, Child Protection, Population Control, and Family Planning Agency (DP3KB) in preventing and addressing cases of violence against children. The research method employed is empirical research, collecting primary data through interviews and observations, as well as secondary data from relevant literature. Findings indicate that DP3KB has implemented prevention programs that include socialization of children's rights and campaigns for reporting violence, although it still faces challenges such as limited resources and lack of inter-agency coordination. The implications of this research highlight the importance of cross-sector collaboration and increased community awareness to protect children from violence. By understanding the steps taken by DP3KB, it is hoped that this can contribute to child protection efforts and the handling of violence cases in Bintan Regency.
Supply-Side Arguments for Tax Reductions, 2017, 2025 or Beyond
Authors: Johnson Clark
Published: December 2024

Tax policy is “on the ballot,” so to speak in the 2024 US Presidential election. Trump’s economic advisors are arguing for an extension of the rate reductions in the 2017 Tax Act, which some have deemed “supply side, as were the Reagan tax cuts during the 1980s. The economic argument for supply side tax rate reductions drew on a policy mix framework developed by Robert Mundell as early as 1962. Within that framework, the easy fiscal/ tight monetary policy solution was intended for circumstances of either pressure on reserves or the exchange rate (as during the Kennedy Administration) or of serious domestic inflation (as under the Carter and Reagan Administrations). Tax cuts in the US since the 1980s have not had the intended stimulus effects because neither the currency weakness nor inflationary preconditions have existed. Absent such conditions, tax rate reductions will generate either domestic over-heating or a redistribution of income to those in higher brackets. Any argument in favor of the 2017 Tax Act, or for a similar tax reduction in 2025 or 2026, should not fall back on Mundell’s policy mix advocacy. In contrast, the case for an easy fiscal/ tight money policy may have unexpected force in situations of fixed exchange rates, or where domestic monetary policy options are otherwise constrained or absent – as has been the case in Eurozone periphery countries.
Enablers and Determinants of Post-digitalisation in the Local Economy
Authors: Stepnicka Nina
Published: December 2024

The notion of post-digitality does not send digitality into oblivion. Instead, it is an impetus for an in-depth, much-needed critical reflection on digital technologies, their often uninvited ubiquity and mutation into unpredictable forms and practices.’

The term ‘post-digital’ appears alongside other terms: ‘post-internet’ (post-internet), “great disruption” (Great Disruption), or “post-web 2.0” (post-web 2.0), which similarly define the end of a phase and the transition to the next phase in the digital age. The use of the prefix ‘post’ e.g. in relation to the industrial era (post-industrial), modernity (post-modern) or the real world (post-real) is seen as a sign of life in transition.

In economics, this phase and the direction of the evolution of the 21st century economy are determined by four features: transformational innovation, the neo-customers, social interactions.

Transformational innovations are the most important game-changer in the 21st century economy and are the result of the disruption of existing ecosystems caused by meeting customer needs with new technology-enabled business models. What this means, therefore, is that, regardless of the industry, companies that have been regarded as market leaders for decades may be displaced by newcomers, and competitive advantage is no longer sustainable in the long term as it was before.

Neoconsumers are consumers, who used to be needs-oriented, while in the post-digital economy they are demand-oriented, have more demands, less time to spend and limited attention spans. Furthermore, neo-consumers in the post-digital economy are entering the role of professional prosumers who, together with actors, design ecosystems, products and services, adapting them to constant change and thus becoming co-owners of them.

Social interactions refer, inter alia, to treating neo-consumers not only as purchasers of products and services, but in particular as consumers communicating experiences to a larger audience, taking into account messages from the immediate environment, other customers and experts.
SYNTHESIS OF ANTIMICROBIAL MODIFIERS BASED ON POLYVINYL ALCOHOL ACYLATED WITH CHLOROANHYDRIDE OF MALEOPIMARIC ACID
Authors:   Sumgait State University, Sumgait, Azerbaijan, S. Pirguliyeva Matanat
Published: December 2024

The water-soluble form of of maleopimaric acid (MPA) as its ester with polyvinyl alcohol (PVA) has been prepared by reaction of (PVA) with chloroanhydride of MPA in the conditions of interphase catalysis. The optimal conditions of the acylation reaction of PVA with chloroanhydride of MPA have been determined, the catalyst allowing to obtain the water-soluble polyester with yield to 52 % has been chosen. The tests of samples of modifiers for antibacterial activity against Gram-positive and Gram-negative strains of bacteria have been carried out.
ENHANCING BREAD QUALITY: EFFECTS OF SMALL AND MECHANICALLY DAMAGED STARCH GRANULES IN LOCAL WHEAT FLOUR
Authors:   Faculty of Industrial Viticulture and Food Production Technology, Shahrisabz branch of Tashkent Institute of Chemical Technology, Shakhrisabz, Uzbekistan, Mirzayev Jamol
Published: December 2024

This study investigates the impact of small-sized and mechanically damaged starch granules on the quality and shelf life of bread made from high-grade local and imported wheat flours. By separating these damaged granules, we aimed to enhance bread quality indicators such as freshness, moisture retention, structural integrity and overall longevity without the use of synthetic additives. The results demonstrated that bread made from flour with separated starch granules consistently retained higher freshness scores, exhibited better moisture retention, had a higher swelling capacity, showed reduced crumbling and maintained lower firmness over time compared to control samples. These findings suggest that the separation process provides a natural, cost-effective solution to improve bread quality, offering significant benefits for the bakery industry and aligning with consumer preferences for natural and environmentally friendly products.
THE PHASE DIAGRAM OF THE In2Se3-SrInSe2 SYSTEM AND THE PHOTO- AND ELECTROPHYSICAL PROPERTIES OF THE OBTAINED PHASES
Authors:   Baku State University, Baku, Azerbaijan, Yagubov N.I.
Published: December 2024

Using the methods of physico-chemical analysis: differential-thermal analysis (DTA), X-ray diffraction (XRD), microstructural analysis (MSA), as well as density and microhardness measurements, the chemical interaction in the In2Se3-SrInSe2 system was studied and its phase T-x diagram was constructed. The phase diagram of the system is quasi-binary and eutectic. The composition of the eutectic formed between the compounds In2Se3 and SrInSe2 is 35 mol % SrInSe2, with a melting point of 720°C. According to the results of the microstructural analysis in a system based on the In2Se3 compound, the solid solution region reaches up to 7 mol % SrInSe2 and based on SrInSe2, the solubility is 10 mol % In2Se3. The temperature dependences of electrical conductivity and thermoelectric driving force, as well as the spectral dependence of photoconductivity of solid solution alloys (In2Se3)1-x(SrInSe2)x (x=0.01; 0.03; 0.05), have been studied.
Ice and snow sports behavior recognition based on multi-scale features and improved CBAM
Authors: Liu Chunping
Published: December 2024

Accurately identifying and correcting erroneous sports behaviors of athletes or beginners in ice and snow sports can improve the training quality. However, ice and snow sports scenes often have complex motion backgrounds, and the behavioral features during motion are difficult to extract, which affects the recognition accuracy. In order to solve the feature extraction in ice and snow sports behavior recognition, a behavior recognition model based on multi-scale features and improved convolutional block attention module is proposed. The model first utilizes multi-scale features to obtain multi-level features from the collected ice and snow motion images, ensuring that features of different scales in the images can be effectively captured. Then, one-dimensional convolution and spatial random pooling layers are introduced to improve the convolutional attention module, thereby constructing a behavior recognition model. The accuracy of the proposed model in the Ski-Pose dataset was 98.3%, which was 8.2% and 13.7% higher than other recognition models, indicating an obvious gap. The accuracy and F1 value were 89.5% and 91.2%, respectively, and the recognition rate for small targets reached 80%, which verified the effectiveness of the model. The research provides new technological support for intelligent monitoring and analysis systems for ice and snow sports.
Wpływ postępowania karnego i postępowania w sprawie o przestępstwo skarbowe na status komornika sądowego
Authors: Kowalski Sebastian
Published: December 2024

The article presents the dogmatic-legal analysis of the impact of penal proceedings and proceedings concerning a fiscal crime on the status of a bailiff. This impact involves an option of suspending a bailiff in activities when proceedings are initiated against him or her or upon the expiry under law of the appointment of a bailiff to the official position and the option to dismiss him or her from the position upon passing a final and valid judgement concerning a crime or a fiscal crime. According to the author, the present regulations of this problem in the Act on bailiffs, although generally correct, do require an intervention of the legislator. The author deems as unacceptable, first of all, no possibility to revoke a decision to suspend a bailiff in activities if the basis of a suspension has been the presentation of an alleged crime or a fiscal crime, regardless of how long the proceedings continue or of their outcome and the expiry of the appointment to the official position of a bailiff sentenced for a wilful act prosecuted on the basis of private prosecution, even if its commitment had nothing to do with the fulfilment of an official function.

Keywords: suspension of a bailiff, termination of appointment, dismissal, conviction
Pozostawienie należności przypadającej wierzycielowi hipotecznemu na rachunku depozytowym – zagadnienia praktyczne
Authors: Mikołajczak Michał
Published: December 2024

Keeping Receivables Due to a Mortgagee on a Deposit Account – Practical Aspects
The article presents problems related to keeping a receivable due to a mortgagee on a deposit account of the Minister of Finance. Based on examples from enforcement practice, the author points out difficulties involved in the proper determination of the value of a liability secured with mortgage, which is to be included in a distribution plan of sums recovered from enforcement against real estate.
Issues concerning a type of enforcement title have been described in particular, which entitle a creditor to receive funds deposited on an account of the Minister of Finance. Due to the concision of statutory regulations, the author pays also much attention to problems in interpretation relating to the determination of regulations that apply to a deposit, rules of its reception and liquidation. The article indicates possible procedures for transferring to the deposit of the Minister of Finance of amounts that correspond to liabilities that have already expired.
In the final part, effects have been presented of submitting receivables that are due to a mortgagee to the deposit of the Minister of Finance, including but not limited to negative consequences that result from the lack of redemption of liability for which funds have been paid to the deposit.

Keywords: enforcement, real estate, liability, mortgage, deposit
Doręczenie komornicze jako nieegzekucyjna czynność komorników sądowych
Authors: Czyszkowski Paweł
Published: December 2024

This study deals with service made by a court enforcement officer after the amendments to the Law of 22 March 2018 as non-enforcement activities of court enforcement officer. In the study it was demonstrated that the scope of these activities makes the judicial officer closer to an entrepreneur, contrary to the legislature’s declaration in the Act. Attention is also drawn to the procedural difficulties that may arise in connection with the practical application of the provisions discussed. The study points out the scope of these activities and the connection with other provisions including art. 139(1) of the Code of Civil Procedure.

Keywords: court enforcement officer, businessman, service of correspondence, bailiff fees
From Belief to Action: Political Efficacy as Predictor of Social Media Political Participation Among Students
Authors:   University of the Cordilleras, Cadelina Kathlyn Princess
Published: December 2024

The impressive rise of social media has made political participation through digitally networked avenues more prevalent. In exploring universities and youth political engagement, it can be concluded that the youth have started to create a voice and began participating in politics in ways they know. Using explanatory sequential mixed method, this study investigated the level of political efficacy (PE) and the extent of social media political participation (SMPP) of student voters. It also determined the relationship between PE and SMPP. This is to examine how their PE plays a role in better understanding their participatory habits and conclude an explanation in the youth’s political engagement through the platform. The study has determined that there is a moderate positive relationship between the overall level of PE and overall extent of SMPP among student voters. Based on the findings, it is recommended to promote strategies that enhance student’s PE and SMPP in order to cultivate well-informed individuals who are equipped to express their political views in a healthy and constructive manner.
Transforming Healthcare: The Role of Artificial Intelligence in Revolutionising Patient Care
Authors: Pan Dr Ritika
Published: December 2024

Artificial Intelligence (AI) has emerged as a powerful tool in the healthcare industry. It has enhanced patient care, diagnostics, treatment planning, and operational efficiency. This article explores the diverse applications of AI. Machine learning algorithms, natural language processing, and predictive analytics reshape clinical practices. These technologies allow healthcare providers to focus more on patient care by enhancing diagnostic accuracy, personalising treatments, and automating tasks. However, challenges such as data security, algorithmic bias, and ethical concerns must be addressed for AI to be fully integrated into healthcare. Overcoming these obstacles will enable AI to revolutionise patient outcomes and healthcare innovation.
DESIGN AND STATIC ANALYSIS OF PRISMATIC PRESSURE VESSELS ACCORDING TO TS 13445-3 STANDARD
Authors:   Trakya University Engineering Faculty, Dilara Dogan Munise , Çalpan Osman ,   HPO TECH, Altinbalik M. Tahir ,   Trakya University Engineering Faculty
Published: December 2024

The focus of the presented work is on the design and analysis of prismatic pressure vessels. Engineering calculations, design parameters and performance criteria of pressure vessels are available in the literature in detail, but there are deficiencies in the evaluation of the manufacturing processes of prismatic pressure vessels and the mathematical formulae required by these processes in the light of standards. In this context, it was investigated how a special prismatic pressure vessel, a square profile hyperbaric oxygen chamber, could be optimised in terms of structural strength, stress distribution and safety requirements. The material selection and design of such a chamber has been evaluated using DBA and DBF methods. The performance of the prismatic hyperbaric oxygen chamber in current applications is explained, supported by various engineering analyses and simulations. It was observed that the cabin designed in accordance with TS 13445-3 standards is 2 times safe under operating conditions and the amount of displacement is commercially acceptable. It is shown with SolidWorks analysis.
NANOTUBULAR OXIDE FORMATION ON BIOMEDICAL TITANIUM ALLOYS
Authors:   Institute of Metal Science, equipment, and technologies with Center for Hydro- and Aerodynamics “Acad. A. Balevski”, Veselinov Deyan , Yankova Radostina ,   Institute of Metal Science, equipment, and technologies with Center for Hydro- and Aerodynamics “Acad. A. Balevski”, Koeva Veneta ,   Institute of Metal Science, equipment, and technologies with Center for Hydro- and Aerodynamics “Acad. A. Balevski”
Published: December 2024

Titanium and its alloys, particularly commercially pure titanium (cpTi, Grade 2) and Ti-6Al-4V Extra Low Interstitial (ELI), are widely used in biomedical implants due to their excellent biocompatibility and mechanical properties. Surface modifications such as nanotubular oxide formation can further enhance their biological performance by improving osseointegration, corrosion resistance, and antibacterial properties. In this study, cpTi and Ti-6Al-4V ELI were anodized to form nanotubular titanium oxide layers. The anodization process was carried out in an ethylene glycol-based electrolyte containing ammonium fluoride, with an applied potential of 80 V for 30 minutes.
Scanning Electron Microscopy (SEM) and Energy Dispersive Spectroscopy (EDS) were used to characterize the morphology and chemical composition of the resulting oxide layers. SEM analysis revealed well-organized nanotubular structures on both alloys, with an average inner diameter of approximately 90 nm and nanotube lengths of about 1.1 microns. However, the Ti-6Al-4V ELI alloy exhibited voids in the nanotubular layer, corresponding to regions of the beta phase. EDS analysis confirmed the presence of titanium dioxide (TiO₂) as the primary component of the oxide layer, with the Ti-6Al-4V ELI alloy also showing traces of aluminum, vanadium, and fluorine incorporated during the anodization process.
These results demonstrate that both cpTi and Ti-6Al-4V ELI can form nanotubular oxide layers with distinct morphological and compositional features. The differences in nanotube density and the presence of alloying elements in Ti-6Al-4V ELI suggest potential influences on the mechanical and biological properties of the anodized surfaces, making them suitable for tailored biomedical applications.
Implementation of Augmented Reality with Marker Based Tracking on Custom Gift Products by Tricksy.co
Authors: Raisa Mutia Thahir  , Jasmine Aulia Mumtaz  , Kinaya Khairunnisa Komariansyah  , Wien Kuntari
Published: December 2024

This research explores the integration of Augmented Reality (AR) technology into custom gift products by Tricksy.co to create a more interactive and personalized gift-giving experience. By utilizing EyeJack Creator, a platform for creating AR photo markers, the system allows customers to design gifts that display personalized videos when scanned. The process includes generating AR markers, integrating QR codes, and ensuring compatibility with both iOS and Android devices. System testing confirmed that the AR markers successfully displayed the videos as intended, with smooth functionality across different platforms. However, slow internet connections impacted the speed of AR content downloading. This study highlights the potential of AR to revolutionize the gift industry by adding a unique digital layer to physical gifts, offering both emotional and interactive value.
Review of TOGOBM study
Authors: Jain Rajesh
Published: December 2024

In this TOBGM study, Intervention started very late, with OGTT performed an average of 15.6 weeks. And this is why it results in a modest reduction in primary outcome in the immediate treatment arm (24.9% Vs. Control group (30.5%), adjusted risk reduction 5.6%. OGTT was performed in less than 14 weeks in 23.2% of Women only, and most of the women were beyond the 14th week at entry level in both the Intervention and control groups. Insulin and Metformin use was more in the Treatment arm than in the control arm, 58.1% vs. 41.4% and 23.6% Vs. 10.4%, respectively. Interestingly, more benefits were seen in less than the 14th week of pregnancy.
Profiling targeted therapy responses in ROS1+ non-small cell lung cancer using genomically engineered patient-derived cell lines
Authors:   , Terrones Bernat Marc
Published: December 2024

Lung cancer is a heterogeneous disease that requires tailored therapeutic approaches. Significant advances in molecular understanding have led to the development of targeted therapies, such as tyrosine kinase inhibitors (TKIs) for epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK)-mutated non-small cell lung cancer (NSCLC). However, resistance to these therapies often develops, complicating treatment. This thesis focuses on addressing resistance in ROS1-rearranged NSCLC, a rare molecular subtype. ROS1-rearranged tumors, though only 2% of NSCLC cases, present unique challenges due to limited experimental models and the difficulty of studying rare mutations. The research aimed to create novel patient-derived cell lines carrying ROS1 mutations associated with TKI resistance, allowing for high-throughput drug screening. The CRISPR/Cas9 technique was used to introduce three resistance-conferring mutations (G2032R, L2026M and S1986Y) into the HCC-78 cell line expressing SLC34A2-ROS1. Drug assays using the 5 clinically approved ROS1 TKIs showed varied responses, with G2032R mutation leading to the most aggressive phenotype and highest resistance, while S1986Y showed no resistance. The mutations were then introduced into two additional patient-derived cell lines: CUTO-28 (TPM3-ROS1) and CUTO-37 (CD74-ROS1), revealing that the effect of mutations is dependent on the ROS1 fusion partner. Additionally, transcriptomic analysis of ROS1+ NSCLC revealed an upregulation in pathways related to nucleotide synthesis and cell adhesion, with IL20RB identified as a potential target for treating bone metastases. The study also profiled gene expression changes in response to repotrectinib, a next-generation TKI, and identified overexpressed genes like complement 3 (C3) and epithelial-to-mesenchymal transition (EMT)-related genes that may contribute to drug resistance in G2032R mutant cases. This thesis demonstrates the feasibility of using CRISPR/Cas9 to model rare ROS1 mutations and highlights the importance of fusion partner context in drug resistance. The new panel of 9 TKI-resistant, patient-derived ROS1+ NSCLC cell lines unveiled potential new therapeutic targets for patients with TKI-refractory or bone metastatic ROS1+ NSCLC disease.
Outer-Hop Independent Vertex Cover of a Graph
Authors: Hassan Javier , Gamorez Anabel , Ahmad Eman
Published: December 2024

In this paper, we initiate the study on an outer-hop independent vertex cover of a graph and we characterize this type of set in some special graphs and in the join of two graphs. Moreover, we derive some bounds and formulas of the parameter using the characterization results.
A PERSPECTIVA OMNILATERAL E POLITÉCNICA NO ENSINO MÉDIO INTEGRADO
Authors: Carrijo Elaine Cristina Ribeiro , Ferrari Sandra Aparecida Fernandes Lopes
Published: December 2024

This study presents a bibliographical research in the area of Professional and Technological Education (EPT). It arises from the concern about concepts and principles that underpin Integrated High School Education, especially the principles of omnilaterality and polytechnics. To what extent can this knowledge be presented as a possibility of teaching practice in this teaching modality? The main objective is, based on the knowledge acquired through the research, to contribute, in practice, to reflections on the topic addressed. For this research, the methodology was to carry out a bibliographical and documentary survey, and as a result, we came to the conclusion that the principles of omnilaterality and polytechnics are considered pillars of the Integrated High School modality and that teaching practices in this perspective should focus on the inseparability between work, science, technology and culture, work as an educational principle, research as a pedagogical principle and the integration between general and specific knowledge in a perspective of totality, in the search for the integral formation of human beings.
Fluid Intake and Hydration Responses to Mass Participation Gravel Cycling
Authors: Schuerger Carly , Raik Brandon , Salmon Francis , Foote Kian , Madlambayan Angelo , Vega Maya , Handler Grace , Schubert Matthew M.
Published: December 2024

Gravel cycling is a relatively new cycling discipline, with the Union Cycliste Internationale (UCI) hosting their first World Championships in 2022. Gravel races combine features of road racing, cyclocross, and mountain biking, including terrain of varying technical difficulty, long distances, substantial elevation gain, obstacles, and limited opportunities to stop for in-race nutrition. This study assessed hydration responses to gravel races of three different distances. Data were collected on saliva osmolarity (SOsm), body mass (BM), fluid intake, and nutrition knowledge at a gravel cycling race in April 2023. A total of 121 participants completed pre-race surveys, 53 provided pre-race measures of BM and SOsm, and 38 participants completed post-race testing. Only 22.6% (n = 12) of participants were hydrated before the race, with 56.6% mildly dehydrated (n = 30), 18.9% moderately dehydrated (n = 10), and 1.9% severely dehydrated (n = 1). Post-race, 15% (n=6) were still hydrated, 20% (n = 8) were mildly dehydrated, 47.5% (n = 19) were moderately dehydrated, and 17.5% (n = 7) were severely dehydrated. Analyses revealed significant decreases in BM and increases in SOsm from pre- to post-exercise in the two longer race distances (p < 0.05). There was a significant effect of race distance on energy, fluid, carbohydrate, and sodium intake (p < 0.05). Sweat rates were not different (p > 0.05). Our results revealed an effect of race distance on BM losses, SOsm, and energy, fluid, carbohydrate, and sodium intakes. Future studies could inform optimal feeding and hydration strategies.
Children's TV Educational Programs Effects Analysis: A Case Study of Pakistan
Authors: Khan Huma , Hamza Ameer , Asghar Muhammad
Published: December 2024

Aim of the Study: This research study has been conducted to explore the children TV educational programs effects analysis on the intellect and behavior of children.
Methodology: The researcher has adopted the survey method to conduct this research.  The participants in this research study were kids enrolled in various Bahawalpur schools.  A sample of 500 student respondents was selected randomly from three different age groups for instance; (3-6), (6-12), (13-19). Further; these students were accessed through A class and C class school categorization. Information was gathered regarding the neighborhood's well-known kids' TV networks, including Nickelodeon, Nick Jr., Teen Nick, and Nick Toon. To gather data from a chosen sample, the researcher used the probability sampling technique. Using an open-ended question format and a Likert scale, a standard questionnaire was created as a data gathering tool. The questionnaire for the age group3-6 years was filled by their parents and teachers because; they are unable to register their preferences. However; the collected data was analyzed by using SPSS software to draw inferences.
Findings: The results have revealed that children TV Educational programs hasten the learning and behavior of children. It increases knowledge, vocabulary, cognition, and comprehension for basic subjects like languages, science and math.
Conclusion: The study concluded that TV educational programs are more effectively in the learning and shaping the behaviours of the children. These programs found fundamental in increasing knowledge and vocabulary of the school children.
Managing Multicultural Teams: A Case Study of IT Professionals of Developing Countries
Authors: Saleem Usama , Saeed Abid , Anjum Kainat
Published: December 2024

Aim of the Study: This research aims to explore the challenges faced by managers in managing international multicultural teams and to examine how cultural diversity affects organizational performance, employee performance, and the behavior and expectations of individuals.
Methodology: To achieve this aim, a quantitative study will be conducted using a systematic questionnaire distributed to employees in software companies in Pakistan, Australia, Ukraine, Iran, Nepal, and India. Data will be collected through a web-based system using Google Forms.
Findings: Managers in software development organizations encounter multiple issues when managing culturally diverse teams. To understand and explore these problems, cultural dimensions are utilized. Previous research indicates that common challenges faced by project managers and team members include ineffective communication, differing working styles, and varying expectations.
Conclusion: To address these challenges, it is crucial to embrace diversity and encourage team members to learn and grow from it.
Examining Transgender Community in Pakistani Media: A Content Analysis of English Newspapers
Authors: Siddique Saba , Pasha Saadia Anwar , Sharif Humaira
Published: December 2024

Aim of the Study: Over the past few years, the Pakistani Supreme Court has taken major action to protect transgender people's rights. In a similar vein, the Court ordered municipal governments to change laws in order to safeguard the rights of the transgender population. However, there are differences in how the law and courts perceive transgender identity, which makes the fight for basic rights more difficult. The purpose of this research is to examine and evaluate how transgender individuals are portrayed in Pakistan's top newspapers, Dawn and Express Tribune.
Methodology: To investigate the media's role in promoting social inclusion and bringing attention to the problems encountered by the transgender population, the researchers used quantitative content analysis. The purposive sampling technique was applied to select the newspapers' content, mainly their frequencies, tone, and topics.
Findings: Results showed that the transgender community receives inadequate coverage in newspapers, news reports, and other sections. The newspapers examined in this study did not emphasize placing transgender-related stories and items prominently. Besides, the representations of the transgender community in newspaper content, particularly on op-ed pages were significantly underrepresented.
Conclusion: Thus, it is concluded that media representations and framing of transgender are critical sources influencing the transgender community’s image in Pakistani society. Their affirming depictions of transgender people have the power to alter attitudes and actions toward this community and speak directly to the process of gender identity formation.
Neobrandeisianizm i polityczność ochrony konkurencji
Authors:   Urząd Ochrony Konkurencji i Konsumentów, Polański Jan
Published: December 2024

Wzrost znaczenia tzw. Big Tech doprowadził do wznowienia debat nad rolą prawa ochrony konkurencji. Podczas gdy w Europie dyskusje te przebiegają najczęściej w kontekście konkretnych spraw rozpatrywanych przez organy ochrony konkurencji, w Stanach Zjednoczonych w większym stopniu koncentrują się one na szerszym spojrzeniu na filozofię polityki antymonopolowej. W tym kontekście dominujący – jak się wydaje – pogląd, że prawo konkurencji powinno być coraz bardziej ekonomiczne i coraz mniej „polityczne” jest w ostatnim czasie kwestionowany przez zwolenników tzw. nowego ruchu brandeisiańskiego. Zwolennicy tego ruchu wskazują, że współczesne prawo konkurencji jest w istocie „martwe” i że dla jego odrodzenia konieczne jest przedefiniowanie sposobu jego postrzegania. W artykule omówiona zostaje istota toczącej się obecnie w Stanach Zjednoczonych debaty oraz jej potencjalny wpływ na stosowanie prawa konkurencji w Polsce. W artykule wskazano, że chociaż w prawie polskim tzw. chicagowska rewolucja nigdy nie została w pełni zrealizowana, to polskie prawo może wykazywać tendencję do dalszego dryfowania w kierunku „dobrobytowych” celów prawa konkurencji, które – podobnie jak w Stanach Zjednoczonych – nie muszą przystawać do faktycznej roli, jaka przypada temu prawu. Mając na względzie powyższe, w artykule zasugerowano potrzebę dalszej dyskusji nad celami ochrony konkurencji w Polsce, w tym ordoliberalnych podstaw dla tych działań. W artykule ponadto wskazano, że trudne do przesądzenia jest, na ile prawdopodobny jest długoterminowo sukces zwolenników neobrandeisianizmu, a także że dalszy kształt prawa konkurencji może być determinowany przez czynniki zewnętrzne, które nadają bieg ogólnej dyskusji na temat roli państwa w gospodarce.
An ensemble approach for research article classification: a case study in artificial intelligence
Authors: Lu Min , Tang Lie , Zhou Xianke
Published: December 2024

Text classification of research articles in emerging fields poses significant challenges due to their complex boundaries, interdisciplinary nature, and rapid evolution. Traditional methods, which rely on manually curated search terms and keyword matching, often lack recall due to the inherent incompleteness of keyword lists. In response to this limitation, this study introduces a deep learning-based ensemble approach that addresses the challenges of article classification in dynamic research areas, using the field of artificial intelligence (AI) as a case study. Our approach included using decision tree, sciBERT and regular expression matching on different fields of the articles, and a support vector machine (SVM) to merge the results from different models. We evaluated the effectiveness of our method on a manually labeled dataset, finding that our combined approach captured around 97% of AI-related articles in the web of science (WoS) corpus with a precision of 0.92. This presents a 0.15 increase in F1-score compared with existing search term based approach. Following this, we performed an ablation study to prove that each component in the ensemble model contributes to the overall performance, and that sciBERT outperforms other pre-trained BERT models in this case.
Endorsement of reporting guidelines and clinical trial registration across urological medical journals: a cross-sectional study
Authors: Hagood Alex , Case Joseph , Magee Trevor , Smith Caleb , Nees Danya , Hughes Griffin , Vassar Matt
Published: December 2024

Introduction

Over the years, funding for urologic diseases has witnessed a steady rise, reaching $587 million in 2020 from $541 million in 2018. In parallel, there has been a notable increase in the total number of urology journals from 2011 to 2018. This surge in research funding and journal publications calls for urologists to effectively navigate through a vast body of evidence to make the best evidence-based clinical decisions. Our primary objective was to assess the “instructions for authors” of these journals to determine the extent of endorsement of reporting guidelines for common study designs in medical research.

Methods

Top urology journals were identified using the 2021 Scopus CiteScore and confirmed via Google Scholar Metrics h5-index. In a masked, duplicate manner, two investigators retrieved data from the “instructions for authors” webpages of the included journals. For each journal investigated in our study, the following data were extracted: journal title, 5-year impact factor, email responses of journal editors, mention of the EQUATOR Network in the “instructions for authors,” mention of the ICMJE in the “instruction for authors,” geographical region of publication and statements about clinical trial registration.

Results

Of the 92 urology journals examined, only one-third (32/92) mentioned the EQUATOR network in their “instructions for authors.” A total of 17 journals (17/92, 18.5%) did not mention a single reporting guideline. The most endorsed guideline was CONSORT at 67.4% (62/92). Clinical trial registration was not mentioned by 28 (30%), recommended by 27 (29%), and required by 37 journals (40%).

Conclusion

Our findings indicate that urology journals inconsistently endorse reporting guidelines and clinical trial registration. Based on these results, we propose that urology journals adopt a standardized approach, incorporating explicit requirements for reporting guidelines such as those listed on the EQUATOR Network and clinical trial registration for all relevant study designs. Specifically, journals should consider clearly stating mandatory or recommended guidelines for clinical trials, observational studies, and systematic reviews, among others. Future efforts should focus on evaluating the implementation of these policies and identifying barriers that hinder their adoption.