bluuebunny/crossref_metadata_2025 huggingface dataset:
Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer
Authors: Lu You-Wang , Ding Zhao-Li , Mao Rui , Zhao Gui-Gang , He Yu-Qi , Li Xiao-Lu , Liu Jiang
Published: February 2024

BACKGROUND

Aberrant methylation is common during the initiation and progression of colorectal cancer (CRC), and detecting these changes that occur during early adenoma (ADE) formation and CRC progression has clinical value.

AIM

To identify potential DNA methylation markers specific to ADE and CRC.

METHODS

Here, we performed SeqCap targeted bisulfite sequencing and RNA-seq analysis of colorectal ADE and CRC samples to profile the epigenomic-transcriptomic landscape.

RESULTS

Comparing 22 CRC and 25 ADE samples, global methylation was higher in the former, but both showed similar methylation patterns regarding differentially methylated gene positions, chromatin signatures, and repeated elements. High-grade CRC tended to exhibit elevated methylation levels in gene promoter regions compared to those in low-grade CRC. Combined with RNA-seq gene expression data, we identified 14 methylation-regulated differentially expressed genes, of which only AGTR1 and NECAB1 methylation had prognostic significance.

CONCLUSION

Our results suggest that genome-wide alterations in DNA methylation occur during the early stages of CRC and demonstrate the methylation signatures associated with colorectal ADEs and CRC, suggesting prognostic biomarkers for CRC.
Characteristics and risk assessment of atmospheric PM2.5 heavy metals pollution near coal gangue sites in Huaibei, China
Authors: Yang Kang , Hong Xiuping , Wang Xin , Zhu Yongjie , Zuo Pengtong , Gao Ge
Published: February 2024

To study the level of atmospheric PM2.5 and its heavy metal pollution near the coal gangue mountain, this study analyzed the content of seven heavy metals (Zn, Pb, Cu, Cd, Hg, Ni, Cr) and As through the PM2.5 samples from the vicinity of a large-scale coal gangue filed of Tongting coal mine in Huaibei, and evaluated the level of pollution, sources, and health effects. The results showed that during the sampling period, the average concentration of PM2.5 near the coal gangue field was 169.83 μg·m-3, which was 2.26 times that of the national air quality level Ⅱ daily standard. The coal gangue field may be an important source of air pollution, with the degree of heavy metal and arsenic pollution in the order of Cd, Pb, Zn, Hg (extremely heavy pollution) > As, Cu (medium pollution) > Ni, Cr (light pollution) and coal gangue dust and mining dust contributed more. This study provides data for atmospheric particulate matter and heavy metal and arsenic pollution levels near coal gangue fields and provides a theoretical basis for air pollution prevention and control near coal gangue hills.
Preferencias de los consumidores por leche producida en cumplimiento con bienestar animal en Puerto Rico: Evaluando alternativas para informar al consumidor
Authors: Tavárez Héctor , Cortés Mildred , Gregory Alexandra
Published: February 2024

En años recientes, la industria lechera de Puerto Rico ha estado interesada en producir leche certificada en cumplimiento con el bienestar animal. Sin embargo, es vital examinar dos asuntos principales en términos de mercadeo y política agraria. Primero, es crucial identificar los factores que afectan las preferencias de los consumidores por leche producida en cumplimiento con el bienestar animal. Segundo, es importante entender cómo la información sobre la leche producida en cumplimiento con el bienestar animal debe ser presentada a los consumidores, de tal forma que aumente la probabilidad de compra. Este estudio utilizó una regresión logit para identificar los determinantes que afectan las preferencias por leche producida en cumplimiento con el bienestar animal. Además, el estudio utilizó un modelo logit multinomial para examinar las preferencias por texto, logo y código de respuesta rápida en el envase de leche. Los resultados de la regresión logit revelan que los entrevistados más jóvenes, con mayor educación, mujeres y con menos dependientes tienen mayor interés por leche certificada en cumplimiento con el bienestar animal. Además, las personas que regularmente están interesadas en productos diferenciados tienen mayor interés en la leche producida bajo la certificación de bienestar animal. Los resultados del modelo logit multinomial indican que los participantes prefieren texto y logo sobre el código de respuesta rápida.
ATHELOCA SUBRUFELLA (HULST) (LEPIDOPTERA: PYRALIDAE: PHYCITINAE): THE COCONUT MOTH IN PUERTO RICO
Authors: Cabrera-Asencio Irma , Estévez de Jensen Consuelo
Published: February 2024

ATHELOCA SUBRUFELLA (HULST) (LEPIDOPTERA: PYRALIDAE: PHYCITINAE): THE COCONUT MOTH IN PUERTO RICO
Study of Release Time 25 NM Runway 34 At Airnav Palangka Raya Branch
Authors: Pasa Inda Tri , Tommy Hutabarat Liber , Restiana Rizny , Ramadhini Fadril Deby
Published: February 2024

Bandar Udara Tjilik Riwut memberikan pelayanan lalu lintas penerbangan yaitu Aerodrome Control Tower (ADC) dan Approach Control Procedure (APP). Bandara ini merupakan salah satu bandara penghubung untuk bandara perintis yang ada disekitarnya. Dalam memberikan pelayanan, pendekatan utama yang digunakan untuk runway 34 adalah Instrument Landing System (ILS) dan straight in approach. Selama melaksanakan observasi di Airnav Cabang Palangka Raya, ditemukan sebuah permasalahan yang menimbulkan pendapat berbeda-beda antara ATC yaitu belum adanya pengkajian ulang terkait standar separasi yang tersedia dalam SOP akibat dari adanya penambahan apron baru. Berdasarkan Standar Operasional Prosedur (SOP) Palangka Raya disebutkan bahwa pesawat udara yang akan berangkat dapat dijzinkan masuk landasan saat pesawat udara yang akan mendarat berjarak minimal        25 NM dari Threshold RWY, namun jarak tersebut dihitung dari north apron yang merupakan apron lama dari Bandar Udara Tjilik Riwut menuju RWY 34 sedangkan saat ini Bandar Udara Tjilik Riwut terdapat penambahan apron baru yaitu south apron sehingga perlu adanya pengkajian ulang apakah jarak 25 NM               bisa dijadikan sebagai acuan juga untuk memasukkan pesawat ke landasan apabila pesawat line up dari south apron. Dalam melaksanakan observasi, penulis mengumpulkan data pergerakan pesawat yang akan       berangkat dan yang akan mendarat menggunakan runway 34. Dari observasi yang telah dilakukan dapat disimpulkan bahwa jarak 25 Nm masih layak untuk digunakan sebagai standar untuk memasukkan pesawat ke landasan. Dengan adanya penambahan apron tentu harus ada pengkajian ulang dalam Standar Operasional Prosedur (SOP). Kajian inilah yang diharapkan dapat membantu Airnav Cabang Palangka Raya dalam menentukan standar separasi untuk mengizinkan pesawat masuk landasan dan dengan adanya standar separasi tersebut, diharapkan para ATC dapat mewujudkan pelayanan lalu lintas yang aman dan efektif.
KONSUMSI VITAMIN C DAN ZAT BESI PADA ANEMIA DEFISIENSI BESI
Authors:   Universitas Islam Sumatera Utara, Afriandi Dian , Aktalina Lucia
Published: February 2024

The prevalence of iron deficiency anemia in Indonesia is around 57.1% and often occurs in adolescent girls. Iron deficiency anemia can result in impaired hemoglobin function, low productivity, hampered mental and intelligence development as well as a decrease in the body's immune system and morbidity. Macronutrients such as carbohydrates, proteins and fats are needed in hemoglobin biosynthesis. Likewise micronutrients such as iron, folic acid, vitamin C and vitamin B and micronutrients. This research aims: to determine the intake of vitamin C and iron and the incidence of anemia in students of the UISU Medan medical faculty. This type of research is observation using a cross-sectional design. The population was all students from the second semester of the UISU medical faculty, totaling 134 people. A sample of 50 people was taken randomly. This research showed that 58% of respondents did not consume insufficient amounts of vitamin C and 42% consumed sufficient amounts of vitamin C. The research results showed that 44% of respondents consumed sufficient iron and 56% did not consume enough iron. There were 18% of respondents who suffered from anemia. Conclusion: Based on the Chi square test, there is a significant relationship between iron intake and the incidence of anemia (p value <0.05) and there is no significant relationship between vitamin C consumption and the incidence of anemia (p value > 0.05).
Survey of Dairy Products Using Machine Learning Techniques
Authors: Khaliq Fadel Nour Abd AL , Bahnam Baydaa Sulaiman
Published: February 2024

The quality of dairy is of great importance in the food industry, as dairy is one of the main sources of proteins, calcium, vitamins and minerals that the human body needs. Dairy is found in many products, including milk, cream, and cheese, the most important of which is milk. It represents the basic and important element in people's lives, especially children, because it is an indispensable source for their growth, building their bones, and strengthening their bodies. Milk is a perishable product. Every gram of milk of poor quality or structure can cause tons of milk to spoil, causing significant financial losses and can lead to poisoning. Therefore, the quality and safety standards of this product are essential to ensure the provision of healthy and safe products to consumers. Determining the quality of the milk product is crucial for the purpose of monitoring to reduce potential losses and damages. The aim of this research is to provide a brief survey of the methods used in classifying milk quality using artificial intelligence methods, which include the use of machine learning algorithms through Identifying the most important and accurate methods and displaying the results reached using the known metrics: Accuracy, Precision, Recall, and F1_score.
Sidimi, a dacha village in Ussuri: architectural and planning features
Authors:   Pacific National University, Frolova Natalia A. , Kradin Nikolay P. ,   Pacific National University
Published: February 2024

Sidimi (Sidemi, now Bezverkhovo) in Primorye region is the only surviving (though ruined) complex of country estates in the south of the Russian Far East dating back to the turn of 20th century. Other estates and dacha villages in the region were destroyed or have survived as isolated buildings. Our study of the history of Sidimi and its architectural and planning features helps understand the concept of Far Eastern country architecture. It combines eastern and western stylistic traditions, new architectural trends of the early 20th century and their adaptation to the unique lifestyle in Ussuri taiga.
M. Ginzburg’s functional method as a sustainable tradition in modern architectural design
Authors:   Moscow Architectural Institute, Maksimova Anna D.
Published: February 2024

The article examines the functional creativity method of the architect Moisei Ginzburg, reviews its development over time, and searches for references to its application in modern architectural practice using as an example the project of Alexei Ginzburg - a temporary stay camp located in extreme conditions.
The concept of coloristic treatment of a linear urban structure (on the example of Leninsky prospekt in Voronezh)
Authors:   Voronezh State Technical University, Gurev Sergey N. , Yenin Alexander E. ,   Voronezh State Technical University, Gurev Alexander S. ,   Voronezh State Technical University
Published: February 2024

We examined the pool of colors demonstrated by the natural context of the city of Voronezh and the color palette of the architecture on the Left Bank and the main street Leninsky Prospekt of this district. Based on this study, a conceptual idea is proposed for the color treatment of the city’s extended linear structure. The concept allows for the spatial arrangement of the street, ensuring continuity in the perception of its colors, shapes and spaces and the stylistic features of the buildings. Orientation in the space of the street is improved through the accentuation by color of high-rise dominants, architectural monuments, socially and functionally significant objects, and historical buildings of architectural and artistic interest.
The embodiment of the ecological concept and climatic adaptability in the spatial structure of the traditional chinese dwelling with a courtyard
Authors:   Ural Federal University, Zhang Yimeng , Korotich Andrey V. ,   Ural Federal University
Published: February 2024

The article analyzes the logic and distinctive features of the structural construction of traditional Chinese dwellings with a courtyard. A detailed comparison of various types of such dwellings located in different geographical and climatic regions of China allows us to identify their compositional features and unique architectural solutions. The focus of the study is on the ecological principles and strategies of climatic adaptation of various compositional types of courtyards that allowed them to effectively cope with climatic challenges over centuries. Attention is drawn to the basic philosophical concept of harmonious coexistence of man with nature, which underlies the design of optimal types of traditional Chinese dwellings, particularly to passive methods of architectural design that contribute to environmental sustainability and climatic adaptation of these dwellings.
Socializing the Impact: An Analysis of the Theory of Planned Behavior's Influence on Increasing University Students' Cybersecurity Awareness
Authors: Parikh Varsha , Nimbekar Mansi
Published: February 2024

The study aimed to assess cybersecurity awareness among university students in Vadodara, India, using the Theory of Planned Behavior (TPB) framework. The study involved 242 students from selected universities, selected using a snowball sampling method. Data was collected through Google Forms and email, and the Statistical Package for the Social Sciences (SPSS) programme was used for statistical analysis. The majority of students were young (18-23 years old), with moderate internet usage and primary digital competency skills. Only 17% reported experiencing issues during cyber surfing. The study found that most students had low awareness, lower knowledge, and negative perceptions about cybersecurity. Most students followed unsafe cybersecurity practices and had a negative attitude towards cybersecurity. The study also examined the correlation between TPB constructs.
Legal Reconstruction in Determining a Justice Collaborator in Corruption Crime Cases in Indonesia
Authors:   Faculty of Law, Universitas Singaperbangsa, Gunawan Yopi
Published: February 2024

This research aims to analyze the regulations regarding policies for determining witnesses and reconstructing policies for determining justice collaborators in corruption cases. The type of research used is normative, using an approach to laws and other regulations. The nature of the research is descriptive, using secondary data. Research analysis was carried out qualitatively using a deductive method of conclusion. This research concludes that, in practice, various regulations regulate the policy of determining cooperating witnesses or justice collaborators in criminal acts of corruption. This regulation began with laws and then developed into Circulars and Joint Regulations from law enforcement agencies. Due to differences in rules, the policy for setting new standards had to be changed. This standard must legally bind recognition or recognition and the same understanding or perception regarding the status of cooperating perpetrator witnesses or justice collaborators from the examination stage at the investigation level to the examination stage at the court level, even to the examination stage at the court level.
Do the Total Reward and Talent Management Program Affect the Retention and Performance of Generation Y Employees?
Authors:   Master of Management University of Lampung, Bandar Lampung, Indonesia, Dewi AR Sinta , Ahadiat Ayi ,   Master of Management University of Lampung, Bandar Lampung, Indonesia, Hayati Keumala ,   Master of Management University of Lampung, Bandar Lampung, Indonesia
Published: February 2024

Currently, the Indonesian national workforce is dominated by generation Y. Generation Y is the generation born between 1980-2000. Based on literature studies, this generation is known as the generation that easily leaves the workplace if they see career opportunities. Employees who move easily will affect company performance. With changes in employee demographics, it is important to examine strategies and factors that influence employee retention. This article tries to discuss and explore the factors that influence the retention and performance of generation Y employees through total rewards and talent management programs. This research uses a questionnaire survey conducted on employees of Bank Syariah Indonesia in Lampung Province, Indonesia. A total of 200 generation Y employee respondents in Lampung participated in this research. The analysis model in data processing uses SEM Lisrel 8.8. The findings reveal that total rewards are proven to influence the retention and performance of generation Y employees. The talent management program has no direct influence on the performance of generation Y employees. Intrinsic rewards are proven to have more influence on the retention and performance of generation Y employees. Talent management programs influence the performance of generation Y employees if mediated by retention.
Neuromotricity in early childhood education. Development tables as an interdisciplinary proposal according to the BAPNE method
Authors: Romero Naranjo Francisco Javier , Andreu-Cabrera Eliseo , Arnau-Mollá Antonio Francisco
Published: February 2024

The aim of this research is to review the basis of neurodevelopment in early childhood education and provide interdisciplinary development tables that encompass cognitive, kinesthetic, and musical aspects. After reviewing numerous authors, and in order to provide early childhood education teachers with a reliable overview of the subject, we present here tables that are always conditioned by genetic and environmental factors. The development tables offer guidance information in areas such as language, motor coordination, gross motor skills, fine motor skills, spatio-temporal relationships, time horizons, logic, numerical relationships, and rhythmic motor, melodic, and socio-musical aspects, among others.
Keywords: Neurodevelopment, Neuromotricity, Bapne, Body percussion, cognitive functions, executive functions.
Suporte social para acolhimento de irmãos de prematuros em UTI neonatal:"caderninho de histórias para colorir e brincar" / Social support for siblings of premature infants in nicu: the “notebook of stories to color and play”
Authors: Ruas Teresa Cristina Brito , Gagliardo Heloisa GRG , Françozo Maria de Fátima de Campos , Mello Bernadete Balanin Almeida , De Freitas Márcia , Albuquerque Raquel Costa
Published: February 2024

O nascimento de um bebê prematuro e sua internação trazem mudanças na rotina familiar e sofrimento para os irmãos. Práticas humanizadas em UTIN promovem ações focadas no núcleo familiar e acolhimento. Esta proposta apresenta material lúdico de suporte social para acolhimento dos irmãos de prematuros. Propomos um “Caderninho de Histórias”, para que os irmãos compreendam o ambiente neonatal, as necessidades do bebê e elaborem sentimentos decorrentes da ausência dos pais. Esperamos que esse material fortaleça vínculos afetivos familiares para que sejam continuados após alta hospitalar. AbstractThe birth of premature babies and their hospitalization changes family routine and causes suffering for siblings. The humanization in NICUs is focused on the family nucleus and on holding them. We present ludic material as a means of supporting siblings coping with the new situation. A “Notebook of Stories” for siblings was devised to help them understand the neonatal environment, the baby's needs, and to help them elaborate feelings arising from the absence of the parents. We expect this material to strengthen family bounds which may last after hospital discharge.Keywords: Infant Premature, Holding, Social Support, Sibling Relations, Humanization of Assistance.ResumenEl nacimiento de un bebé prematuro y su hospitalización traen cambios en la rutina familiar y el sufrimiento de los hermanos. Las prácticas humanizadas en la UCIN promueven acciones enfocadas en el núcleo familiar y la recepción. Esta propuesta presenta material lúdico de apoyo social para dar la bienvenida a los hermanos de bebés prematuros. Proponemos un "Cuaderno de historias", para que los hermanos entiendan el entorno neonatal, las necesidades del bebé y los sentimientos elaborados que resultan de la ausencia de los padres. Esperamos que este material fortalezca los lazos afectivos familiares para que puedan continuar después de alta hospitalaria.Palabras clave: Recien Nacido Prematuro, Acogimiento, Apoyo Social, Relaciones entre Hermanos, Humanización de la Atención.
Análise da qualidade de vida, sobrecarga de cuidadores e desempenho ocupacional de idosos: percepção da terapia ocupacional
Authors: AZAMBUJA MARTINS ELIS , FLORES ROSO BRUNA , ARAÚJO XIMENES AGUIAR PALMA KAYLA
Published: February 2024

Introdução: O aumento das doenças crônicas e perdas no desempenho ocupacional tornam os idosos dependentes de terceiros. O cuidador é o principal sujeito que desempenha esse papel. Contudo, diante do cotidiano de cuidado, existem fatores que influenciam na saúde. Objetivo: Realizar o levantamento sociodemográfico dos idosos e cuidadores e analisar a relação da qualidade de vida e nível de sobrecarga dos cuidadores com o desempenho ocupacional dos idosos. Métodos: Para coleta de dados, utilizou-se questionário sociodemográfico semiestruturado para cuidadores e idosos; Medida Canadense de Desempenho Ocupacional para idosos; Escala de Sobrecarga do Cuidador de ZARIT; WHOQOL-bref para os cuidadores. A análise estatística foi através do programa Statistical Package for Social Science for Windows. Resultados: Idosos com idade entre 80 e 90 anos com restrição no desempenho ocupacional. Predomínio do sexo feminino entre os cuidadores. Cuidadores informais apresentaram sobrecarga leve e grave e pontuação regular no domínio social relacionado à qualidade de vida. Os domínios psicológico e meio ambiente mostraram-se regulares para todos os cuidadores. Não há correlação significativa entre desempenho ocupacional, qualidade de vida e sobrecarga. Conclusão: O estudo obteve dados importantes para agregar na implementação de ações e espaços de rede de cuidado e suporte para cuidadores, disseminando informações, orientações e educação em saúde, a fim de contribuir com a assistência adequada, qualidade de vida e bem-estar dos idosos.
Palavras-chave: Cuidadores. Idoso. Qualidade de Vida. Terapia Ocupacional
Enhancing Early Diagnosis: Machine Learning Applications in Diabetes Prediction
Authors:   Department of Doctoral Studies, Colorado Technical University, Colorado Springs, CO, USA, Kalla Dinesh , Smith Nathan , Samaah Fnu ,   Department of Computer Science, Harrisburg University of Science and Technology, Harrisburg, PA, USA, Polimetla Kiran ,   Adobe, 345 Park Ave, San Jose, CA, USA
Published: February 2024

Diabetes is a persistent illness that affects a huge number of individuals around the world. Early diagnosis and treatment of diabetes is critical for forestalling difficulties and further developing well-being results. Machine learning procedures offer promising answers for upgrading early diabetes expectations and determination. Based on a variety of data sources, this paper examines the recent machine-learning applications for diabetes prediction. The findings demonstrate that diabetes onset and risk can be accurately predicted using machine learning models applied to biomedical data, wearable device data, and electronic health records. For instance, random forest models utilising fasting plasma glucose, BMI, and age gave 93% precision in diabetes expectations. Profound brain networks utilising genomic and stomach microbiome information achieved 89% exactness. Machine learning techniques show excellent performance for diabetes prediction across diverse data types. Challenges remain in model interpretability and integration into clinical workflows. Further research on predictive feature selection, model optimisation, and clinical implementation will enable enhanced early diabetes diagnosis through machine learning. With accurate and early prediction, patients can receive prompt treatment to manage diabetes progression better.
Data Quality Improvement Strategies for Data Analysis Specific to the IT Industry
Authors:   Senior Data Consultant, MD, USA, Devineni Siva Karthik
Published: February 2024

In the ever-evolving landscape of the IT industry, data acts as the foundational element driving decisions, strategies, and innovations. The quality of data significantly influences the operational efficiency, decision-making accuracy, customer satisfaction, and overall success of IT initiatives. Poor data quality leads to erroneous insights, and ineffective strategies, and could potentially cost companies millions, making data quality improvement not just an option but a critical necessity. This paper explores the multifaceted importance of maintaining high data quality in the IT industry and outlines various strategies for improvement. It talks about big-picture methods, including sorting out data, keeping it up-to-date, using technology to improve accuracy and trustworthiness, and ensuring timeliness. This article explains methods IT specialties and groups should use to check and fix their data quality. These steps will help keep the information accurate and valuable for better results in the future
Strategi Humas PT Bank Sumut dalam Meningkatkan Citra Positif melalui Media Jurnalistik
Authors: Kurnia Balqis Putri Salwa , Saragih M. Yoserizal , Abidin Syahrul
Published: February 2024

The use of the internet by public relations practitioners gives them additional power to carry out their duties, because all digital PR activities can be easily accessed by the public wherever and whenever they want. If we look at modern society which is inseparable from the internet and electronic devices, using the internet is very effective because it gives everyone a new way to fulfill their daily needs. The type of research carried out in this research is qualitative research, namely research based on post-positivist philosophy, used to examine the condition of natural objects. The results of this research show that the public relations strategy in improving the image through journalistic media is publications that carefully carry out public relations activities such as publicity, publications, news, press releases, and maintaining the company's reputation and various internal activities.
Peran Humas Puskesmas Tanjung Morawa dalam Menyosialisasikan Penyebaran Stunting Melalui Media Sosial
Authors: Indriana Loula Umaiyah , Saragih M. Yoserizal , Abidin Syahrul
Published: February 2024

Stunting is a condition where a toddler experiences failure to develop due to acute nutritional deficiencies. Tanjung Morawa subdistrict is one of the subdistricts whose working area was designated as a stunting locus by the Deli Serdang regent. Limited publicity on stunting and the difficulty of approaching the public makes it difficult for public relations to maximize its role. This research aims to determine the role, obstacles and successes of Tanjung Morawa Community Health Center public relations in socializing the spread of stunting through journalistic media. The theories used are the theory of the four roles of public relations and the theory of communication barriers. The research method used is a descriptive method with a qualitative approach. Data collection techniques using interviews and observation. The results of the research show that the Public Relations Officer of the Tanjung Morawa Community Health Center has carried out all its roles well, although there is still one role which has been carried out less than optimally, namely as a communications technician. The biggest obstacle for public relations in carrying out its role is community behavior, while the success of public relations in carrying out its role is the freeing of 2 stunting locus areas which are the responsibility of and are under the auspices of the Tanjung Morawa Community Health Center.
Tourism Communication Model Based on Local Wisdom
Authors: Andri Andri , Dunan Amri
Published: February 2024

Gunung Padang is a tourist destination with unique beauty and uniqueness in the Karyamukti Village area, Campaka District, Cianjur Regency, West Java Province. The concept of conveying tourism information based on regional distinctiveness is traditional or local cultural activities that are still practiced in an area. In the development of tourism destinations, there is a pattern of interaction that exists between stakeholders, both between groups, groups with individuals, or individuals with groups. This study aims to describe the form of information delivery with regional distinctiveness at the Gunung Padang Cultural Heritage Site and analyze tourism communication between stakeholders, such as stakeholders and residents, related to efforts to develop regional tourism. This study uses qualitative research methods. Tourism communication at the Gunung Padang Cultural Heritage Site involves various institutions such as the Department of Culture and Tourism of Cianjur Regency, the Cultural Heritage Preservation Center of Banten, and the Tourism Department of West Java Province. This necessitates a longer bureaucracy and coordination process for tourism management. The Department of Culture and Tourism consistently seeks input from managers and the local community in formulating policies for developing tourism efforts at the Gunung Padang Cultural Heritage Site to ensure the successful implementation of programs.
Branding and Tourism in Komodo
Authors: Limbono Pricillia , Lolita Theresia Lavietha Vivrie
Published: February 2024

Accommodation's competitiveness around Labuan Bajo currently drives them to strive after the COVID-19 pandemic to offer a variety of promotions on its products and services to increase brand awareness and expected visits to the super-priority destination on Komodo Island, East Nusa Tenggara. The study aims to explore how Mohini Resort Komodo, of accommodation in Labuan Bajo, performed the influencer marketing strategy for raising brand awareness through Instagram influencers in such a challenging situation. This descriptive and qualitative case study used in-depth interviews and observations to gather the idea. From the viewpoint of the two-step flow theory of communication, this study elaborates on how brands in the travel industry can use the influencer marketing framework to interact with Instagram influencers as online opinion leaders. The findings show that the resort has put into practice an influencer marketing strategy that includes 1) identifying the marketing objective, target market, and definition of success; 2) defining the best campaign strategy; 3) outlining the creative, creator, and content strategy; and 4) defining budget, target, and media planning. This research contributes to an ongoing examination of the framework for companies in the tourism industry to enforce effective influencer marketing.
Implications of the Role of Tourism Carrying Capacity in the Development of Sustainable Tourism Destinations
Authors: Haribudiman Irwan , Berliandaldo Mahardhika , Holman Fasa Angga Wijaya
Published: February 2024

Tourism contributes to increasing global and national Gross Domestic Product (GDP) growth. However, there are also negative impacts on tourism activities. One of the implementations to minimize negative impacts can be carried out by applying the carrying capacity of the destination (tourism carrying capacity/TCC). This study aims to determine the implications of the role of tourism carrying capacity in sustainable tourism development, which focuses on the causality relationship between tourism destination governance policies and tourism carrying capacity (TCC). This study uses a qualitative library/desk study method with a Driving Forces, Pressures, State, Impacts, and Responses (DPSIR) framework analysis approach. The five dimensions of the carrying capacity of tourism destinations used in the DPSIR framework are territorial, governance, economic, social, and environmental. As a result, three framework findings and strategic analysis implications were obtained. First, it required the restoration of natural resources, environment, and ecosystems; second, carrying out integrated planning in land use, economic growth, strengthening socio-demographics, and a sustainable environment; third, educating tourists to transform the attitude, behavior, and ethics of tourists. The overall strategic analysis framework aligns with various tourism development programs to maintain natural, economic, social, and environmental balances that apply sustainable tourism by implementing stakeholder cooperation.
Assessing the Geo-Strategic Implications of France’s Withdrawal from the Sahel
Authors: Harouna Assoumi , Karim Abdoul
Published: February 2024

Since their independence, postcolonial Sahelian republics have lived in the shadow of Paris, as the French have maintained enormous influence over their former African colonies, particularly those in the Sahel region. France’s self-proclaimed decades-long restoration of relations with Sahelian countries has achieved varied outcomes. France’s relations with the five Sahelian countries have been hampered by a colonial heritage that France has been hesitant to admit. Furthermore, it has been harmed by the years that followed African independence in the early 1960s, as well as by “França frique” – an era defined by collusion and involvement with illegitimate regimes. However, much has changed, and France is now facing opposition from Francophone Sahelian republics and communities. This has resulted in France’s economic, political, and military departure. The geostrategic consequences of France’s disengagement from the Sahel are examined in this study. A comprehensive desk review including secondary data is used in the paper. The paper concludes that France’s disengagement from the Sahel has far-reaching consequences. First, Salafi-Jihadist extremist organizations have discovered new leeway for maneuver (and more armaments), fomenting and exploiting sectarian and ethnic conflicts in countries that are multi-ethnic and multi-faith due to their often artificial colonial origins. Second, the French withdrawal will exacerbate geopolitical conflicts between Great Powers and Area Boys like Algeria.
Understanding Consumer Trends in Setting Up a Lucrative Marketing Strategies
Authors: Awofadeju Martins O. , Ademiju, Teslim A. , Karaduman Ilkay
Published: February 2024

Businesses all over the world strive to convince customers to buy their goods and services. To do this, they research consumer needs and develop marketing plans that will persuade customers to buy. Numerous marketing strategies are used to sway consumer behavior, which ultimately affects their purchasing decision. In present business world that is highly competitive, understanding consumers trend in setting up a lucrative marketing strategies dictate the tune in achieving a successful and effectual marketing rewards. The main objective of this study is to explore how consumer trends can be utilized to develop effective marketing strategies. To achieve this goal, the study analyzed both primary and secondary data. Primary data was collected through observation, interviews, and surveys, while secondary data was obtained from a variety of sources such as newspapers, magazines, trade journals, blogs, online data storage platforms, and government institutions like the Chamber of Commerce, Census Bureau, and labor department. Appropriate marketing tools analysis such as SWOT, PEST and situational analysis are adopted in the study to analyse the relevant data collected from both the primary and secondary sources in order to achieve the objectives of the study. The analysis indicates that grasping consumer trends plays a crucial role in designing effective marketing strategies. It helps in formulating appropriate techniques for each strategy and ensures their effectiveness. Understanding consumer trends is the key to making the strategies responsive to their needs and preferences. Creating successful marketing strategies requires steadfastness, planning, research, and analysis of important policies to understand consumer trends.
Unveiling Impact of Electron Beam Optics on Weld Attributes in EN30B Steel
Authors: Singh Vasundhara , Roy Gour Gopal , Srirangam Prakash
Published: February 2024

The influence of electron optics in terms of beam oscillation (BO) has been studied on weld quality of several steels and reported to develop cosmetic weld with smooth surface and enhanced weld properties. However, effect of electron BO on the weld quality of medium carbon low alloy steel, especially EN30B, has not reported well and investigated in this study. By manipulating magnetic lens in-line with electron beam, the diameter of oscillating beam (OD) and its effect on weld quality has been studied. The OD was changed between 0.5 mm and 2 mm. Numerous tests, including X-ray diffraction, scanning electron microscopy (SEM), Electron Backscattered Diffraction (EBSD), hardness, wear, and tensile, were used to characterize the weld quality. Welds with BO significantly lowered the heat input rate than welds without oscillation. In presence of BO, retained austenite (RA) in the weld increased and it became least in welds made without BO. Tensile residual stress was found in the fusion zone (FZ) and it was higher with BO, especially with higher OD. In contrast to columnar grains predominantly found in welds made without BO, significant equiaxed grains were identified in welds made with BO. Nonmetallic inclusions (NMIs) in the weld became finer and less by use of BO. Introducing BO enhanced the hardness and reduced wear rate of weld, particularly at greater beam OD. Although weld strength was diminished in comparison to the base metal (BM), BO increased the weld's ductility and strength.
 
Received: 26 October 2023 | Revised: 15 January  2024 | Accepted: 18 January  2024
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
Exploring the Landscape of Alertness-Enhancing Drugs: A Contemporary Review
Authors: Triveni Turre  , Ankita Raut  , Apurva Deshmukh  , Milind Umekar
Published: February 2024

This review paper explores the multifaceted concept of alertness, encompassing its diverse meanings, connections with wakefulness, general mechanisms of action of alertness-producing drugs. Alertness spans a continuum from heightened vigilance to a state of overall readiness, and its nuanced interpretations are examined across various disciplines, neurobiology. The paper critically analyzes the existing literature on alertness-producing drugs, ranging from traditional stimulants like caffeine to modern pharmaceuticals like modafinil. The mechanisms of action, efficacy, and potential side effects associated with these drugs are scrutinized. Additionally, natural compounds and herbal remedies acknowledged for their impact on alertness are explored. The review delves into the interplay between alertness and wakefulness, shedding light on their connections and distinctions. By synthesizing knowledge from theoretical frameworks to practical applications, this review serves as a comprehensive resource for researcher and individuals interested in the multifaceted nature of alertness and the pharmacological tools available for its modulation
Ensaio teórico sobre o contributo de exercícios multicomponentes em idosos de Moçambique
Authors: Chavane Félix Salvador , Tchonga Francisco Almeida , Manjate José Luis Sousa , Morais Danilo Barbosa , Rocha Saulo Vasconcelos
Published: February 2024

Este ensaio tem como objetivo abordar o contributo da implementação de Exercício Multicomponente (EM) na vida de pessoas idosas residentes em Moçambique (país em desenvolvimento), bem como, confrontar com as ações ligadas à execução das políticas públicas sociais de proteção adstritas a esse grupo populacional. Para a escrita do ensaio, para além das reflexões dos autores, foi realizada uma revisão de literatura da especialidade, bem como, a discussão de documentos oficiais de políticas públicas em vigor em Moçambique.
AVALIAÇÃO DA QUIMIORRESISTÊNCIA EM CARRAPATOS RHIPICEPHALUS (BOOPHILUS) MICROPLUS
Authors: Guzman Kelly Johana Ramirez , Penagos Angela Natalia Castillo
Published: February 2024

Introdução: A infestação por carrapatos é um dos principais problemas de saúde pública no mundo, e a quimiorresistência em carrapatos vem ocorrendo ao longo do tempo principalmente por o uso inadequado dos compostos inseticidas produzindo assim um impacto econômico negativo na produção ganadera, e a resistência que estos carrapatos tem é um dos maiores problemas já que a disponibilidade de novos antiparasitários e cada vez mais escassa. Objetivo: avaliar a resistência de carrapatos Rhipicephalus microplus a diferentes compostos ixodicidas em uma produção bovina localizada na periferia de Ibagué−Tolima, Colômbia. Material e Métodos: Foram coletadas teleóginas com tamanho maior que 7 mm a quais não foram expostas aos acaricidas mencionados por pelo menos 15 dias antes; após coletá las foram lavadas e secadas. depois; foram feitos grupos homogêneos em peso de dez teleóginas para cada composto mais o grupo controle; e foram preparados 100 ml de solução para imergir cada grupo em seu respectivo composto durante 3 minutos e o grupo controle foi imergido em água destilada. Estes grupos foram incubados a uma temperatura de 28°C e umidade relativa de 80% por 18 dias; As massas de ovos foram depositadas em seringas de 10 ml, selando-as de um lado e deixando um pedaço de algodão do outro e foram incubadas novamente por 20 dias. A eficiência reprodutiva (ER) foi determinada (ER= peso da massa de ovos/peso dos grupos do teleóginas x % eclosão x 20000), e a eficácia do produto (EP) foi determinada ( EP= ER grupo controle - ER grupo tratado/ ER grupo de controle x 100). Resultados: a eclosão no composto organofosforado foi 0%, ER= 0 e EP=100%; Para o composto amidina a eclosão foi de 93,5%, ER=9833,3 e EP=2,41% e no composto piretróide a eclosão foi de 89,3%, ER= 9173,6 e EP= 5,94%. No grupo controle evidenciou-se eclosão de 95,3% e ER 9753,7. Conclusão: Os carrapatos Rhipicephalus microplus da fazenda "EL CURAL" localizada em Ibagué-Tolima, Colômbia; apresentaram resistência a Piretroides e Amidinas. O composto organofosforado teve o maior nível de eficácia, sendo, portanto, a melhor opção para realizar um controle químico.
„Zu hohe Mieten allein können nicht die Begründung sein“
Authors: Tewes Werner
Published: February 2024

Das Geschäft soll gut laufen, trotzdem meldet die KaDeWe-Gruppe Insolvenz an. Wie kann das möglich sein? Detlef Specovius, Insolvenzexperte von der Kanzlei Schultze & Braun, im Interview.
Zoll verteuert Fisch aus Russland
Authors: Sachsenröder Delphine
Published: February 2024

Verarbeiter müssen für Tiefkühl-Fisch aus russischen Fanggebieten künftig einen Aufpreis zahlen. Noch sind die Lager in Deutschland gut gefüllt. Doch wann schlagen sich die Mehrkosten im Markt nieder?
„Es gibt viel zu tun“
Authors: Himberg Mathias
Published: February 2024

Verena Bentele hat als blinde Biathletin Medaillen bei den Paralympics gewonnen und ist heute Präsidentin des Sozialverbands VdK mit mehr als zwei Millionen Mitgliedern. Mit der LZ spricht sie darüber, was der Handel ändern sollte, wenn er wirklich barrierefrei werden will.
Snacks mit Mehrwert, wohin man schaut
Authors: Ingelmann Anja
Published: February 2024

Einige Trends und Entwicklungen in der Süßwaren- und Snack-Branche haben sich verfestigt, neue sind hinzugekommen: Marktforscher geben auf der ISM Einblicke in das Verbraucherverhalten und liefern Ansätze für die Industrie.
Seehofers Erbe
Authors: Vetter Bernhard
Published: February 2024

Frankfurt a.M. Die Windkraftwerke in der Nordsee haben im vergangenen Jahr weniger Strom geliefert. Grund sind Abregelungen wegen Engpässen im Stromnetz. So zahlen alle Stromverbraucher für die Folgen bayerischer Politik.
An extensive analysis of Brazil and the Netherlands determinants of football attendance
Authors: Edel Matthijs
Published: February 2024

Understanding attendance at football stadiums holds great significance for sports economists and football clubs. Consequently, extensive research has been conducted to analyze the factors influencing football stadium attendance. However, much of this research has been confined to short-term analyses or focused solely on European countries. This study seeks to broaden the scope by examining long-term trends in the Netherlands and exploring the dynamics in Brazil. In the Netherlands, factors such as unemployment and overall interest in football emerge as significant determinants of stadium attendance. Surprisingly, hooliganism does not appear to have a notable impact, and the influence of leisure time is unclear. In the Brazilian context, stadium capacity and goal difference do not show significant effects on attendance, and the impact of the club's division is ambiguous.
Challenges in the post-covid-19 world
Authors: Taques Fernando H.
Published: February 2024

The COVID-19 pandemic has unleashed profound social and economic effects, leaving an indelible mark on societies worldwide. Socially, the crisis has exacerbated existing inequalities, disproportionately impacting vulnerable communities and widening the gap between socio-economic strata. Lockdowns, social distancing measures, and the shift to remote work have altered the fabric of daily life, prompting reflections on issues ranging from mental health strains to the digital divide. Economically, the pandemic has triggered widespread job losses, business closures, and disruptions to global supply chains, resulting in economic recessions and financial hardship for individuals and businesses alike. The challenges in the COVID-19 context extend beyond immediate concerns, encompassing the daunting tasks of rebuilding economies, addressing structural weaknesses, and fostering resilience in the face of ongoing uncertainties. In this context, evidence that shows the impact of the pandemic and the effects in the subsequent period is relevant to guide policies and new economic and social relations.
Segurança pública
Authors: Rex Danielson Felipe
Published: February 2024

The present course conclusion paper analyzes the foundations and justifi cation of the creation of Federal Law No. 13,142/2015, as well as its repercussion on the Brazilian legal system. In this perspective, the subjects that make up the provisions of Articles 142 and 144 of the Federal Constitution will be detailed, exposing all the characteristics surrounding the qualifi er exposed in Article 121, § 2, item VII of the Penal Code. Furthermore, it will present the doctrinal understandings in relation to the new qualifi er, that is, functional homicide, expressed in the normative text, to avoid the practice of crime to the disfavor of public security subjects. Moreover, the crime of personal injury committed against public security agents will be briefl y exposed, as well as the very serious and followed-up injuries committed against them, all of which are included by Law No. 13,142/2015.