bluuebunny/crossref_metadata_2025 huggingface dataset:
Las letras de Pascual Contursi en la consolidación formal del tango
Authors: Longoni Torti Bruno
Published: October 2022

Los estudios en tango han erigido a Pascual Contursi (1888-1932) a la condición de fundador del tango-canción y sus dos situaciones axiales, amuros y milonguitas, encarnados respectivamente en “Mi noche triste” y “Flor de fango”. Sin embargo, una revisión estilística de sus tangos pone de relieve el crucial aporte de Contursi a los principios de simetría contrastiva y condensación que consolidaron la estructura del tango en sus diversas expresiones artísticas. En lo formal, el afianzamiento de versos isométricos aunados por la rima aguda, la tensión entre la descripción estática y la narración dinámica, la ambientación minimalista, el dialogismo teatral del apóstrofe, contrapunto entre el yo y tú líricos, así como el sistemático empleo del lunfardo cuya adopción entraña, de suyo, una oposición a la variedad estándar de la lengua. Hallazgos semejantes contribuyen a recalibrar la impronta contursiana de poeta ingenuo y esquemático.
Update for Duchenne Muscular Dystrophy - Hope for Causal Treatment of a Disorder Presenting in Early Childhood?
Authors: Walter Gerhard Franz
Published: October 2022

Duchenne muscular dystrophy (DMD) is a lethal muscle wasting disease that affects 1 in 3,600 to 6,000 males. DMD is not curable until today. In this mini-review, myoblast transplantation and stem cell therapy, read-through therapy, antisense oligonucleotide-mediated therapy, vector-mediated gene therapy, and CRISPR/Cas9-mediated gene editing are shortly addressed, approaches which alone or combined have the potential for causal treatment of DMD.
project providing clinical input to youth justice services informed by principles of trauma-informed practice
Authors: Griffiths Craig , Archard Philip John , Levy Alexander , Hardy Stevie-Jade , Bowlay-Williams Jeanette , Lord Kayleigh
Published: October 2022

Abstract: This article describes an innovative initiative based on principles of trauma-informed care which involves clinicians from a specialist child and adolescent mental health service (CAMHS) team providing input to youth justice services. At a local level, the project seeks to help address recognised gaps in service provision whereby children and young people involved with the criminal justice system are afforded inconsistent access to care and treatment yet recognised as being at increased risk for having experienced early adversity and suffering mental health difficulties. The article takes stock of the project’s development via reference to three interlinked strands of work it incorporates: work supporting staff; direct work with children and young people; and training workshops for professionals. Reference is also made to the findings of an evaluation of the project. In so doing, the article adds further support to arguments for a senior clinician role in CAMHS provision linked to youth justice services, and the necessity of staff training to embed this role and support the recognition of trauma.
Perceptions of Portuguese Doctors Regarding Hastened Death Scenarios: A Cross-Sectional Study
Authors: Pereira Eva , Marina Sílvia , Ricou Miguel
Published: October 2022

Introduction: A growing number of countries have legalized the process of hastening death. At a time when laws decriminalizing hastened death have been passed in the Portuguese Parliament, the development of research related with decision making regarding this issue is of crucial importance. This study seeks to evaluate, in a sample of Portuguese doctors, whether the presentation of clinical vignettes changes the agreement with the practice of hastened death compared with general scenarios.Material and Methods: A questionnaire was distributed among academic physicians from medical schools across Portugal to assess their level of agreement or disagreement with the practice of hastened death. The questionnaire included eight standard cases and eight clinical vignettes framed under conditions defined by law for the practice of hastened death. Differences were analyzed using the t-Student test for paired samples.Results: There were statistically significant differences in five scenarios (t = 3.46; p < 0.05; t = 2.47; p < 0.05; t = 4.28; p < 0.05; t = 3.38; p < 0.05; t = 3.66; p < 0.05) with greater agreement concerning the clinical vignettes. The highest acceptance was found in the requests made by adults with terminal and incurable illnesses.Conclusion: Agreement increased when the clinical vignette was presented in comparison with the respective standard for most of the cases of hastened death presented.
SPOTIFY: listening mediators and algorithmic arrangements
Authors: Girardi Júnior Liráucio , Ribeiro Heitor
Published: October 2022

The essay develops a brief history of the practices of production and fruition in the platformization of musical experience and aims to understand how new digital environments change the conditions of experience with music in the contemporary world. The focus of the analysis is the Spotify platform, as a mediator of listening, based on the changes in the modes of recording, distribution, and consumption of music through digital platforms - and its complex processes of dating and orientation by algorithmic logic.
THE SR. BACANA BRAND IN COVID-19 PANDEMIC: affective memory on Instagram
Authors: Gonzales Lucilene dos Santos , Molini Tatiana Cristina
Published: October 2022

The micro brand Sr. Bacana from Bauru reinvented itself in the pandemic when it was launched on social media Instagram. To differentiate his business from the commodities market, he bet on the affectionate memory of his warm and good- humored grandfather, who has been selling sugarcane juice and coconut water for 30 years in the city. The methodology began with the bibliographic foundation on the brand, advertising, and social media Instagram for an analytical description of the brand's history and communication in its first year of existence, reaching almost 30,000 followers. We identified three stages in Sr. Bacana's journey: 1) launch of the brand; 2) brand connection; 3) the brand as a digital influencer.
IMAGES OF PALMAS: cultural consumption in profile @descubraotocantins
Authors: Ramos Luciélia de Aquino , Mara Miranda Cynthia
Published: October 2022

O presente artigo busca analisar o consumo cultural da imagem de Palmas, capital do estado do Tocantins, a partir da divulgação institucional das imagens da cidade publicadas no perfil do Instagram @descubraotocantins gerido pela Agência do Desenvolvimento do Turismo, Cultura e Economia Criativa do Estado do Tocantins.  A pesquisa foi realizada a partir da coleta de imagens da capital postadas no perfil. Foi efetuada análise crítica e de conteúdo das imagens com o objetivo de propor reflexões sobre o consumo cultural das imagens. A análise apontou para uma seleção limitada e muitas vezes repetida com alternância de ângulos, selecionadas de forma aleatória de terceiros. Pode-se afirmar que a ausência de produção imagética própria do perfil limita a diversidade que a cidade oferece e que poderiam apresentar potencial turístico.
THE CHALLENGES OF ENVIRONMENTAL HEALTH ON THE SCIENCE CURRICULUM ON THE LAST YEARS OF ELEMENTARY EDUCATION, IN THE STATE OF TOCANTINS
Authors: Suarte Letícia Brito de Oliveira , Lagares Ferreira Silva Kellen , Simone Seibert Carla
Published: October 2022

Environmental Health is an area of knowledge that goes through many curricular components, especially in the Natural Sciences, an important field to develop it. It should be related to the teachers' preparation to work in a critical way with a bias towards scientific literacy. This study aimed to evaluate the challenges faced by teachers in the area of Natural Sciences to implement Environmental Health in the Final Years of Elementary School, in the state of Tocantins. A quantitative and qualitative research identified a high percentage of young teachers, with higher prevalence to teach expository lessons and little appropriation of scientific literacy. Although the teachers indicated little difficulty in working with the themes of Environmental Health, they reported the need for continued education.
A GAMIFICAÇÃO COMO INSTRUMENTO DE AMPLIAÇÃO DO ENGAJAMENTO NO PROGRAMA #TEUFUTURO
Authors: Martins Amilton Rodrigo de Quadros , Rosa Pagliarini Eduardo , Kalil Fahad , Pazinato Ariane
Published: October 2022

As gerações atuais de estudantes são cada vez mais influenciadas pela cultura digital, pela tecnologia e por jogos. Porém, as instituições de ensino ainda não conseguem alinhar essa ligação dos jovens com a tecnologia com um método de ensino que consiga engajar o aluno no aprendizado. Assim, surge a gamificação como um meio de estimular uma participação mais ativa dos alunos nas salas de aula. Logo, o objetivo deste estudo é verificar a efetividade da gamificação no aumento de engajamento em estudantes participantes do programa #TeuFuturo da Faculdade Meridional (IMED). Essa é uma pesquisa qualitativa, realizada por meio de um grupo focal, coletando os dados em gravação de áudio e vídeo, com um grupo de 7 alunos do 3º ano do Ensino Médio que fizeram parte do programa. Com a análise dos dados obtidos, foi possível perceber que a gamificação teve um impacto positivo no engajamento dos estudantes.
GAMIFICATION AS AN INSTRUMENT FOR ENHANCING THE ENGAGEMENT ON #TEUFUTURO PROGRAM
Authors: Martins Amilton Rodrigo de Quadros , Rosa Pagliarini Eduardo , Kalil Fahad , Pazinato Ariane
Published: October 2022

Current generations of students are increasingly influenced by digital culture, technology, and games. However, educational institutions still cannot align this connection that young people have with technology with a teaching method that can engage the student in learning. Thus, gamification emerges as a means of stimulating more active participation of students in classrooms. Therefore, the objective of this study is to verify the effectiveness of gamification in increasing engagement in students participating in the IMED #TeuFuturo program. This is qualitative research carried out through a focus group, collecting data through audio and video recording, with seven 12th grade high school students who were part of the program. The analysis of the obtained data made it possible to observe that gamification had a positive impact on the students' engagement.
RESHAPING THE WORK AND IDENTITY OF JOURNALISTS: research reflections on the Covid-19 pandemic
Authors: Figaro Roseli , Moliani João Augusto , Pachi Filho Fernando Felício , Nonato Cláudia
Published: October 2022

This article reflects on the professional identity of journalists. The analysis is based on a survey conducted by the CPCT-ECA/USP in 2021 with professionals from all states in Brazil who work in journalism and journalism-related areas. The results showed that more than half of the respondents identified themselves as journalists. This information was based on the respondents’ own descriptions of the roles and activities they perform as journalists. We first present the research data, discuss what professional identity is and its link to values, and lastly, we present our final considerations.
RECONFIGURAÇÕES DO TRABALHO E DA IDENTIDADE DE JORNALISTAS: reflexões com base em pesquisa no período de pandemia de Covid-19
Authors: Figaro Roseli , Moliani João Augusto , Pachi Filho Fernando Felício , Nonato Cláudia
Published: October 2022

Este artigo traz uma reflexão acerca do que se delineia como identidade profissional dos jornalistas. A análise parte de uma pesquisa  realizada pelo CPCT-ECA/USP em 2021, e cujo corpus é composto por respostas dos profissionais de todos os Estados, que trabalham no jornalismo e em áreas correlatas. A relação das respostas válidas apontou que mais da metade dos respondentes declarou se identificar como jornalista; informação que vem acompanhada, ao longo da pesquisa, pela declaração da função e da atividade que realizam como jornalistas, razão que nos levou a essa reflexão. Para tanto, apresentamos os dados da pesquisa, discutimos o que se entende por identidade profissional, vinculada a valores e, por fim, fazemos algumas ponderações à título de conclusão.
The Influence of The Addition of Potato (Solanum Tuberosum) And Extract of The Skin of The Dragon Fruit on The Level of Flow and Organoleptic Ice Cream
Authors: Meilani Delia , Purwanti Yunika , Fera Melly , Daryono Daryono
Published: October 2022

Potato is one of the tubers that can be used as an alternative source of non-fat solids in the manufacture of ice cream, which can act as an emulsifier that functions to slow down the melting power of ice cream. As for the coloring material, dragon fruit peel extract is used because it has a purplish red pigment and is rich in anthocyanin content as a natural dye. This study aims to determine the level of melting of potato ice cream and the organoleptic properties of ice cream with the addition of potatoes and dragon fruit peel extract as natural dyes. The method used in this study was a completely randomized design (CRD) with two factors, namely factor 1 combination of full cream milk: potato (25:75; 50:50; 75:25) and factor 2 the addition of dragon fruit peel extract (10 ml, 20 ml). ml, 30 ml) with 3 replications. The best treatment results were K₃E₃, namely the composition of 75gr full cream milk and 25 gr potatoes, 30 ml dragon fruit peel extract, which resulted in the highest score on aroma (3.84), color (3.86), texture (4.30), and liking (3.96).
Enzimatic Kinetics of Cellulose Hydrolysis using Cellulase from Goat Rumen Fluids
Authors: Wijonarko Gunawan , Purbowati Ike Sitoresmi Mulyo , Maksum Ali
Published: October 2022

In line with the depletion of petroleum reserves from fossils, humans have forced people to look for alternative renewable energy sources. Nipah plant stems are organic material that contains a lot of lignocellulose. Cellulose in lignocellulose can be hydrolyzed to glucose to produce bioethanol. Problems arise because hydrolysis using pure cellulase requires relatively high costs, so it is necessary to find an alternative source of cheap cellulase. One of the cheap sources of cellulase is goat rumen fluid. Until now, there is not much information regarding the reaction kinetics and cellulase characteristics of goat rumen fluid. The purpose of this study was to isolate crude cellulase extract, determine the KM and Vmax values ​​and determine the optimum temperature and pH. The research was carried out at the Unsoed Agricultural Technology Laboratory. The samples used were seven rumen fluids. The study began with isolation followed by enzymatic kinetics studies. Fractionation was carried out by adding ammonium sulfate salt (50, 60,70, and 80 %), and centrifugation at 7,000 rpm at 4 oC for 15 minutes. Crude cellulase extract with the highest enzyme activity value was used for the study of enzymatic reaction kinetics and characterization. The crude cellulase resistance test to temperature was carried out at 45, 55 and 65 oC and the pH was carried out at pH 4, 5, 6, 7 and 8. The KM and Vmax values ​were determined by measuring the activity of crude cellulase extract at various concentrations of CMC (1, 1 ,5, 2, 2.5, and 3 %). The results showed that crude cellulase extract had an average specific activity of 1.7356 IU/mg. The highest enzyme activity was 0.9854 IU/ml. The optimum crude cellulase extract was at pH 6 with an activity of 1.1015 IU/ml and a temperature of 60 oC with an activity of 0.7829 IU/ml. At a CMC concentration of 2.5% crude cellulase extract had an activity of 0.3179 IU/ml with a Vmax value of 0.0045 IU/ml and a KM of 0.0252 %.
ANALISIS KUALITAS BIOBRIKET KARBONISASI TEMPURUNG KELAPA DAN KULIT SINGKONG DENGAN PEREKAT TEPUNG SINGKONG
Authors: Ropiudin Ropiudin - , Syska Kavadya
Published: October 2022

One of the steps that can be taken to overcome fossil fuel sources is the use of renewable energy sources, especially renewable energy sources. The transfer of energy sources from fuel oil to renewable energy sources is expected to reduce the level of dependence on petroleum. Utilization of agricultural waste, plantation waste or industrial waste is an alternative fuel substitute by converting it into biobriquettes. Coconut shells and cassava peels are agricultural wastes that can be used as materials for making biobriquettes and their availability is quite abundant in Indonesia. This study aims to determine the characteristics of coconut shell and cassava peel carbonized biobriquettes, determine the effect of material composition and adhesive percentage on the quality of coconut shell and cassava peel carbonized biobriquettes. This study used a completely randomized design (CRD) with a combination of 9 experimental variations. The experiment was repeated 4 times so that 36 experimental units were obtained. The treatment factors used in this study were the percentage of adhesive (P0 = 3% adhesive, P1 = 5% adhesive, P2 = 7% adhesive) and material composition (K0 = 80% coconut shell carbonized powder and 20% cassava peel carbonized powder, (K1 = 75% coconut shell carbonized powder and 25% cassava peel carbonized powder, (K2 = 70% coconut shell carbonized powder and 30% cassava peel carbonized powder). The variables observed in this study were water content, ash content, volatile matter content, evaporated, bound carbon content, calorific value, density, and compressive strength. The data obtained were analyzed using the F test and DMRT test at 5% level. The results showed the characteristics of carbonized biobriquettes of cassava peel and coconut shell using cassava flour adhesive, namely water content ( 6.71-7.75%), ash content (4.16-4.63%), volatile matter content (2.01-2.18%), bound carbon content (85.53-87.02% ), calorific value (6709.29-8142.82cal/g), density (0.57-0.74 g/cm3), and compressive strength (3.36-7.66 kg/cm2). The composition of the material and the percentage of adhesive have a significant effect on the moisture content, ash content, volatile matter content, bound carbon content, calorific value, density, and compressive strength.
The Nutritional Content of Egg and Blood’s Lipid Profile of Layer Fed by Kepok Banana Meal (Musa paradisiaca L.) as Feed Supplement
Authors: Leke Jein Rinny , Wantasen Erwin , Siahaan Ratna , Sompie Florencia
Published: October 2022

This study was aimed to evaluate the nutritional of content of egg and the fat profile of layers by feeding of kepok Banana flour (Musa paradisiaca formantypica) as feed supplement. A total of 200 laying 58-week-old hens were used in the study, with 5 treatments and 5 replications, each of which was filled with 8 chickens. The treatments were applied in a completely randomized design, continued with Duncan’s test. The treatments given by kepok banana flour were 0%, 5%, 10%, 15% and 20% substitution of corn flour. This research was conducted for 8 weeks. The parameters measure included egg crude protein (%), egg crude fat (%), egg white crude protein (%), egg yellow fat (%), egg cholesterol (mg/100 g), blood cholesterol (mg/dl), blood LDL cholesterol (mg/dl), and blood HDL cholesterol (mg/dl) of the laying hens. The results showed that the utilization of kepok banana flour up to 20% substitution of yellow corn had a highly significant effect on egg protein content, egg white protein, egg fat content, egg cholesterol content, chicken blood cholesterol, chicken blood HDL, chicken blood LDL and triglycerides of chicken blood. It was concluded that kepok banana flour substitution of up to 20% as a feed source  can increase the nutritional content of chicken eggs and the fat profile of laying hens.
Chemical Composition and Organoleptic Properties of Emulsion-Type Lamb Meat Sausage with Different Fat Levels
Authors: Iswoyo Iswoyo , Sumarmono Juni , Setyawardani Triana , Sampurno Adi , Wibowo Cornelius Hari
Published: October 2022

Various lamb-based processed products have become popular in many countries, including Indonesia that are well known for lamb satay, lamb curry, grilled lamb, and others. Processing lamb meat into sausages is a potential alternative to diversify lamb-based processed food. This study aims to develop a lamb-based processed product in form of emulsion sausage. We used mixed lamb meat and fat of Batur lamb (0, 5, 10, 15, 20 and 25%) that was coarsely ground and added with 2.0% salt, 0.5% dextrose, 0.5% garlic powder, 0.5% pepper powder, 0.3% paprika powder and 0.5% chili powder. Meat, fat, and other ingredients are mixed evenly and then put into collagen casings and measured 10-cm long. Next, the sausage was steamed for +45 minutes, then cooled and drained. We used an experimental method with a Completely Randomized Design (CRD) assigning 6 treatments and 4 replicates. The treatments included T0: Lamb sausage without fat; T1 : Lamb sausage + 5% fat; T2 : Lamb sausage + 10% fat; T3 : Lamb sausage + 15% fat; T4 : Lamb sausage + 20% fat and T5 : Lamb sausage + 25% fat. The observed characteristics of sausages were chemical content (moisture, protein, fat, and ash content) and organoleptic properties (preferred colour, aroma, texture, taste, and acceptability). F test (anova) results showed that the treatment had a significant effect (P<0.05) on the moisture, protein, fat, and ash content of lamb sausage, as well as on preference for colour, aroma, texture, taste, and acceptance of lamb sausage. The results showed that the addition of 10% lamb fat produced emulsion-type lamb sausage with the most optimal characteristics, containing 63.290% water, 15.245% protein, 12.518% fat and 2.536% ash. The preferred colour, aroma, texture, taste and acceptance have satisfied the neutral criteria.
Mapping the Non-Structural Transmembrane Proteins of SARS-CoV-2
Authors: Thomas Sunil
Published: October 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the disease COVID-19 has wreaked havoc on the health and economy of humanity. In addition, the disease is observed in domestic and wild animals. The disease has impacted directly and indirectly every corner of the planet. Currently, there are no vaccines and effective therapies for COVID-19. SARS-CoV-2 is an enveloped virus with a single-stranded RNA genome of 29.8 kb. More than two-thirds of the genome comprises Orf1ab encoding 16 non-structural proteins (nsps) followed by mRNAs encoding structural proteins, spike (S), envelop (E), membrane (M), and nucleocapsid (N). These genes are interspaced with several accessory genes (open reading frames [Orf] 3a, 3b, 6, 7a, 7b, 8, 9b, 9c and 10). The functions of these proteins are of particular interest for understanding the pathogenesis of SARS-CoV-2. Several of the nsps (nsp3, nsp4, nsp6) and Orf3a are transmembrane proteins involved in regulating the host immunity, modifying host cell organelles for viral replication and escape and hence considered drug targets. In this paper we report mapping the transmembrane structure of the non-structural proteins of SARS-CoV-2.
A Proof Of The Riemann Hypothesis Based On A New Expression Of The Completed Zeta Function
Authors: Zhang Weicun
Published: October 2022

Based on the Hadamard product $\xi(s)= \xi(0)\prod_{\rho}(1-\frac{s}{\rho})$, a new expression of $\xi(s)$ is obtained by paring $\rho$ and $\bar{\rho}$ $$\xi(s)= \xi(0)\prod_{i=1}^{\infty}(1-\frac{s}{\rho_i})(1-\frac{s}{\bar{\rho}_i})=\xi(0)\prod_{i=1}^{\infty}\Big{(}\frac{\beta_i^2}{\alpha_i^2+\beta_i^2}+\frac{(s-\alpha_i)^2}{\alpha_i^2+\beta_i^2}\Big{)}$$ where $\xi(0)=\frac{1}{2}$, $\rho_i=\alpha_i+j\beta_i$ and $\bar{\rho}_i=\alpha_i-j\beta_i$ are the complex conjugate zeros of $\xi(s)$, $0<\alpha_i<1$ and $\beta_i\neq 0$ are real numbers, $\beta_i$ are in order of increasing $|\beta_i|$, i.e., $|\beta_1|\leq|\beta_2|\leq|\beta_3|\leq \cdots$.\\ Then, by the functional equation $\xi(s)=\xi(1-s)$, we have $$\xi(0)\prod_{i=1}^{\infty}\Big{(}\frac{\beta_i^2}{\alpha_i^2+\beta_i^2}+\frac{(s-\alpha_i)^2}{\alpha_i^2+\beta_i^2}\Big{)} =\xi(0)\prod_{i=1}^{\infty}\Big{(}\frac{\beta_i^2}{\alpha_i^2+\beta_i^2}+\frac{(1-s-\alpha_i)^2}{\alpha_i^2+\beta_i^2}\Big{)}$$ i.e., $$\prod_{i=1}^{\infty}\Big{(}1+\frac{(s-\alpha_i)^2}{\beta_i^2}\Big{)}=\prod_{i=1}^{\infty}\Big{(}1+\frac{(1-s-\alpha_i)^2}{\beta_i^2}\Big{)}$$ which, by Lemma 3, is equivalent to $$\alpha_i= \frac{1}{2}, i =1, 2, 3, \cdots, \infty$$ Thus, we conclude that the Riemann Hypothesis is true.
A New Albomycin-Producing Strain of Streptomyces globisporus Subsp. globisporus May Provide Protection for Ants Messor structor
Authors: Zakalyukina Yuliya V. , Pavlov Nikolay A. , Lukianov Dmitrii A. , Biryukov Mikhail V. , Marina Valeria I. , Belozerova Olga A. , Tashlitsky Vadim N. , Guglya Elena B. , Osterman Ilya A.
Published: October 2022

There are several well-studied examples of protective symbiosis between insect-host and symbiotic actinobacteria, producing antimicrobial metabolites to inhibit host pathogens. These mutualistic relationships are best described for some wasps and leaf-cutting ants while a huge variety of insect species still remains poorly explored. For the first time we isolated actinobacteria from harvester ant Messor structor, and evaluated the isolates’ potential as antimicrobial producers. All isolates could be divided into two morphotypes of single and mycelial cells. We found that the highest frequency of occurrence of mycelial morphotype was observed among soldiers, and the lowest among larvae in the studied laboratory colony. The representative of this morphotype was identified as Streptomyces globisporus subsp. globisporus 4-3 by polyphasic approach. It was established using E. coli JW5503 pDualRep2 system, that crude broths of mycelial isolates inhibited a protein synthesis in reporter strains, but it did not disrupt the in vitro synthesis of proteins in cell-free extracts. Active compound was extracted, purified and identified as albomycin δ2. Pronounced ability of albomycin to inhibit the growth of entomopathogens suggests that Streptomyces globisporus subsp. globisporus may be involved in defensive symbiosis with the Messor structor ant against infections.
Aerosol Mineral Dust Pollution over Nicosia, Cyprus, April 2019
Authors: Yukhymchuk Yuliia , Milinevsky Gennadi , Syniavskyi Ivan , Popovici Ioana , Unga Florin , Sciare Jean , Marenco Franco , Pikridas Michael , Goloub Philippe
Published: October 2022

The climate change impacts on some regions of the planet faster and stronger. These areas are known as the hot spots for climate change and Cyprus (Nicosia) in the Mediterranean is one of these spots. This paper aims to analyze the significant changes of atmospheric aerosol characteristics in 2019 and during the extreme event of 25 April 2019. We study the aerosol optical thickness (AOT), Ångström exponent, single scattering albedo, refractive index (imaginary and real parts), size, and vertical distribution of aerosol particles during the event of a high atmospheric aerosol contamination over Nicosia in details. For this purpose, we used the ground-based lidar, observations of the sun-photometer AERONET Nicosia station, satellite products from the Moderate Resolution Imaging Spectroradiometer (MODIS), and back trajectories of air movements calculated using the Hybrid Single Particle Lagrangian Integrated Trajectory Model (HYSPLIT). On 23–25 April, according to lidar and sun-photometer observations, strong aerosol pollution over Nicosia was detected. On April 25, 2019, the AOT value exceeds 1.0 at λ = 440 nm. Analysis of the optical and microphysical characteristics supported that the pollution consists of mainly Saharan dust and partly urban aerosols. This assumption was confirmed by HYSPLIT backward trajectories and MODIS images where air masses containing dust particles came from North Africa and from the Eastern part of Europe.
Acute Effect of Moringa oleifera Seed Extract on Oocyte Maturation, Gonadosomatic Index and Hepatosomatic Index of Brackishwater Catfish, Mystus gulio
Authors: Panda P. P. , Kumar P. , Mallick B. C. , Behera P. , Ghosal T. K.
Published: October 2022

The study was conducted during spawning season (June-July) to evaluate the effect of Moringa oleifera seeds Petroleum Ether extracts (MPE) on gonad development and maturation of Mystus gulio. A total of 72 individual’s adult Mystus gulio (weighing from 72-110 g) were equally distributed in four different experimental groups in triplicate. Animals were fed with four different isonitrogenous and isocaloric diets viz. T1 (control), T2 (0.5 g MPE/kg), T3 (1 g MPE/kg) and T4 (1.5 g MPE/kg) for 35 days. Result of the experiment showed that the significantly (p<0.05) maximum oocytes growth, gonadosomatic index (GSI) value and hepatosomatic index (HIS) value in T3 experimental group followed by T2 group as compared to control. Histological observation of ovary deciphers the comparatively mature oocytes in T3 group. These mature oocytes are characterized by fusion of yolk granules, oil globules and thickening of egg chorion. Feeding with higher dose of MPE (T4) results in fatty liver and hepatocytes hypertrophy. This higher dose negatively affects the oocyte maturation, GSI and HSI of M. gulio. From the study it is concluded that the inclusion of 1 g of MPE/kg diet will improve the oocyte maturation, GSI and HSI in M. gulio cat fish.
Low Carb Diet-Related Quality of Life (QOL) and Health Outcomes
Authors: Selvaraj Mary Magdalene Santa , Gopal Jayashree , Subramaniam Kala
Published: October 2022

To develop a questionnaire to measure the influence of Low Carb Diet Therapy on patients’ Quality of Life, and also assess the effect of Low Carb Diet on biochemical, anthropometric and dietary intake parameters reflecting on the evaluation of care, health status and thus the efficacy of online consultation and review methods during COVID-19 Pandemic. Thirty five patients visiting the Diabetologist / Endocrinologist through online methods prescribed Low Carb Diets were administered the QOL questionnaire in Google Form through WhatsApp at online visit to the doctor and the subsequent visit. Other demographic, biochemical, anthropometric parameters, and diet recall were gathered at baseline and the subsequent review. Exploratory Factor Analysis (EFA), Reliability Analysis (RA) using Cronbach’s alpha, test-retest reliability were done. The questionnaire assessed 15 aspects or questions in the QOL. Exploratory factor analysis suggested a three-factor solution with eigen values >1 and factor loadings >0.3. The first factor contained 5 reliable items, the second factor contained 4 items, third factor with 6 items (with Cronbach’s Alpha= 0.669, 0.884, 0.775 respectively) As hypothesized, the QOL was better among patients following Low Carb Diets with higher levels of happiness, more satisfaction with their life and health and also, their biochemical, anthropometric and intake improved. These findings indicate the efficacy of the Low Carb Diet education on QOL and the influence on biochemical, anthropometric and dietary intake parameters was noted. This also shows the efficacy of online consultation and review methods during Pandemic.
Role of Ozone in Food Industry and Agriculture- A Review
Authors: R Mohanapriya, , R Kalpana , K Vijay Aravinth
Published: October 2022

Food contamination is a critical problem that necessitates ongoing food pathogen control at every stage of the manufacturing process. In the food industry, it is critical to maintain product quality and safety. They can be accomplished in a variety of ways, some of which are more technologically advanced than others. The role, contribution, importance, and influence of ozone as a disinfectant used to regulate and eliminate the presence of unfavourable bacteria in food products, as well as to extend their shelf life and remove unwanted odours, are discussed in the study. Several researchers have studied the qualities and applications of ozone, demonstrating that ozone treatment technology may be used on a wide range of foods, including fruits, vegetables, spices, meat and seafood, and beverages. Besides food industry, ozone is also used in agriculture crop production in the way of soil application, foliar spraying and irrigation. A combination of such papers, as described in this review, can be helpful in determining acceptable ozone treatment parameters as well as factors affecting improved food quality and safety. It also includes a critical assessment of the benefits and drawbacks of ozone’s use in the food industry.
Antidiabetic Activity of Bioactive Compounds in Pleurotus florida using Protein Receptors
Authors: Cherian Beena , Jose Shilpa
Published: October 2022

Diabetes Mellitus (DM) is a chronic metabolic disorder due to the defects of insulin secretion (type 1) and increased cellular resistance to insulin (type 2). Mushrooms were found to be effective for reducing diabetic complications and for decreasing the blood glucose levels. When compared to synthetic drugs, the bioactive compounds isolated from mushrooms seem to be less toxic and free of side effects. The ethanol extracts of Pleurotus florida mushroom was used for the extraction of bioactive compounds. The compounds PFEE-1 to PFEE -14 were screened for drug likeness and molecular properties. For structural molecular biology and computer -assisted drug design, molecular docking is found to be a strong tool. It has been used in an attempt to identify and to expound the mechanism of action of the bioactive compounds in Pleurotus florida with the inhibition of GPCR40, PTPBI, PPAR and DPP4 protein receptor for controlling the blood sugar level. 14 bioactive compounds screened from Pleurotus florida mushroom ethanol extract was docked with the glide software based on the drug-likeness score. Ergosterol was found to be a potent inhibitor of DPP4, GPCR40, PPAR and PTPBI when compared to other bioactive compounds.
Proximate, Physico-Chemical, Nutritive and Anti-Nutritive Assessment of Raw, Boiled and Roasted Kernels of Anacardium occidentale L. var. W210
Authors: A Elangovan , M Madhu Priya , R Priyadharshini , S Ravi Shankar
Published: October 2022

Cashew (Anacardium occidentale L.) is an evergreen perennial tree, originated from Brazil and now widely grown in the tropics. Cashew is a wonder tree crop, where almost all parts of the tree ranging from roots to apples and nuts are used in various fields. The aim of the present investigation is to analyse the kernels (nuts), var. W210 for understanding its proximate, physico-chemical, nutritive and anti-nutritive aspects in three forms, viz., raw, roasted and boiled state. The roasted samples are comparatively rich in crude carbohydrate (43.26±0.86 g), crude protein (22.80±1.22 g) and calorific value (498.32±1.64 k. cal). Highest lipid and fibre content is reported in raw sample as (33.02±0.94 g) and (8.56±1.62 g) respectively. Moisture content (16.65 ±1.88 g) is the highest to be reported in boiled sample. From the results, it has been clearly understood, that the minerals except iron, are rich in roasted than the other two forms. Roasted sample showed the maximum value of nitrogen (3.66±0.47 g), potassium of about 676.3±0.86 mg, calcium of 75.5±0.44 mg, magnesium of 355.4±0.50 mg and phosphorus of 398.6±1.78 mg/100 g. The iron content was high in raw sample of about 7.73±0.77 mg comparatively. The physico-chemical analysis shows that the total ash content was high in roasted sample which is recorded as 3.05±0.82 g. Other parameters such as acid insoluble ash, water-soluble extractive, alcohol soluble extractive values are found higher in roasted state. The results of anti-nutrient analysis gives a transparent idea that the raw sample has high content of phytic acid (0.445±0.004%), tannins (0.787±0.005%), saponins (0.101±0.003%) and oxalate (0.099±0.004%). The study addresses the nutritional and the anti-nutritional aspect of A. occidentale in its three forms and from the results obtained, we can conclude that the roasted form of seeds are found to be nutritionally superior for consumption as foods for humans.
Pro-biotification of Underutilized Manila Tamarind Pulverized Seed Blended with Muskmelon
Authors: Nandikolmath Veeresh , Nandi Priti , Nag Arnab , Maity Subhrajyoti
Published: October 2022

Probiotics are live microorganisms that offer health benefits to consumers by improving their intestinal microflora balance. The word ‘probiotics’ is derived from the Greek term ‘pro’ and ‘biotic’ that means ‘for life’. Many dairy products and fruit pulp juices are added with probiotic flora. Many juices are also prepared using nutraceutically rich fruit seeds. Pitchellobium dulce seeds are rich in saponins, steroids, glycosides, lipids, phospholipids, polysaccharides, and glycolipids. It has anti-oxidant activity, anti-ulcer activity, free radical scavenging activity, anti-fungal activity, and anti-diabetic activity. In the present work, the probiotic juice was prepared using Pitchellobium dulce seed powder, muskmelon fruit pulp, and two Lactic acid bacteria (Lactococcus lactis and Lactobacillus acidophilus). The final product was evaluated for Colony Forming Unit (CFU), pH, sterility, taste, color, flavor, and texture. It was found that the shelf life of the juice at 40C is 3 months. It has shown that its direct consumption helps in reducing gastric ulcers and other gut-related problems, and if the extract is introduced into the nostril, it will reduce chest congestion. People who are allergic or intolerant to milk-based products can also drink the juice. This study aims to serve a delicious and nutritious drink to promote better health and nutrition for the population.
Mobile Health Services for COVID-19: Counseling, Testing, and Vaccination for Medically Underserved Populations
Authors: Gupta Priya Sarin , Mohareb Amir M. , Valdes Christine , Price Christin , Jollife Margaret , Regis Craig , Munshi Nehal , Taborda Eddie , Lautenschlager Miriam , Fox Anne , Hanscom Diane , Kruse Gina , LaRocque Regina , Betancourt Joseph , Taveras Elsie M.
Published: October 2022

Mobile health units can improve access to preventive health services, especially for medically underserved populations. However, there is little published experience of mobile health units being used to expand access to COVID-19 vaccination. In concert with local public health departments and community members, we implemented a mobile COVID-19 health unit and deployed it to 12 predominantly low-income and racial/ethnic minority communities in Massachusetts. We describe the success and challenges of this innovative program in expanding access to COVID-19 vaccination. (Am J Public Health. 2022;112(11):1556–1559. https://doi.org/10.2105/AJPH.2022.307021 )
COVID-19 Vaccine Uptake and Factors Affecting Hesitancy Among US Nurses, March–June 2021
Authors: Rich-Edwards Janet W. , Rocheleau Carissa M. , Ding Ming , Hankins Jennifer A. , Katuska Laura M. , Kumph Xenia , Steege Andrea L. , Boiano James M. , Lawson Christina C.
Published: October 2022

Objectives. To characterize COVID-19 vaccine uptake and hesitancy among US nurses.

Methods. We surveyed nurses in 3 national cohorts during spring 2021. Participants who indicated that they did not plan to receive or were unsure whether they planned to receive the vaccine were considered vaccine hesitant.

Results. Among 32 426 female current and former nurses, 93% had been or planned to be vaccinated. After adjustment for age, race/ethnicity, and occupational variables, vaccine hesitancy was associated with lower education, living in the South, and working in a group care or home health setting. Those who experienced COVID-19 deaths and those reporting personal or household vulnerability to COVID-19 were less likely to be hesitant. Having contracted COVID-19 doubled the risk of vaccine hesitancy (95% confidence interval [CI] = 1.85, 2.53). Reasons for hesitancy that were common among nurses who did not plan to receive the vaccine were religion/ethics, belief that the vaccine was ineffective, and lack of concern about COVID-19; those who were unsure often cited concerns regarding side effects or medical reasons or reported that they had had COVID-19.

Conclusions. Vaccine hesitancy was unusual and stemmed from specific concerns.

Public Health Implications. Targeted messaging and outreach might reduce vaccine hesitancy. (Am J Public Health. 2022;112(11):1620–1629. https://doi.org/10.2105/AJPH.2022.307050 )
Secondary Fracture Rate After Vertebral Osteoporotic Compression Fracture Is Decreased by Anti-Osteoporotic Medication but Not Increased by Cement Augmentation
Authors: Mills Emily S. , Hah Raymond J. , Fresquez Zoe , Mertz Kevin , Buser Zorica , Alluri Ram K. , Anderson Paul A.
Published: October 2022

Background:

Painful vertebral osteoporotic compression fractures (OCFs) are often treated with cement augmentation, although controversies exist as to whether or not this increases the secondary fracture risk. Prevention of secondary fracture includes treatment of underlying osteoporosis. The purposes of this study were to determine (1) whether cement augmentation increases the rate of secondary fracture compared with nonoperative management, (2) whether anti-osteoporotic medications reduce the rate of secondary fracture, and (3) the rate of osteoporosis treatment with medications following vertebral OCF.

Methods:

The PearlDiver database was queried for all patients with a diagnosis of OCF from 2015 to 2019. Patients were excluded if they were <50 years old, had a diagnosis of spinal neoplasm or infection, or underwent lumbar fusion in the perioperative period. Secondary fracture risk was assessed using univariate and multivariate logistic regression analysis, with kyphoplasty, vertebroplasty, anti-osteoporotic medications, age, gender, and Elixhauser Comorbidity Index as variables.

Results:

A total of 36,145 patients were diagnosed with an OCF during the study period. Of those, 25,904 (71.7%) underwent nonoperative management and 10,241 (28.3%) underwent cement augmentation, including 1,556 who underwent vertebroplasty and 8,833 who underwent kyphoplasty. Patients who underwent nonoperative management had a secondary fracture rate of 21.8% following the initial OCF, compared with 14.5% in the vertebroplasty cohort and 18.5% in the kyphoplasty cohort, which was not a significant difference on multivariate analysis. In the entire cohort, 2,833 (7.8%) received anti-osteoporotic medications and 33,312 (92.2%) did not. The rate of secondary fracture was 10.1% in patients who received medications and 21.9% in those who did not, which was a significant difference on multivariate analysis (odds ratio = 1.23, p < 0.001).

Conclusions:

Cement augmentation did not alter the rate of secondary fracture, whereas anti-osteoporotic medications significantly decreased the risk of subsequent OCF by 19%. Only 7.8% of patients received a prescription for an anti-osteoporotic medication following the initial OCF.

Level of Evidence:

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Unconventional Bradenhead Cementing in the Delaware Basin Case History
Authors: Pelton Ben , Adam Derek , Granier Garrett , Turner William , Tellez Diego , Willis John
Published: October 2022

This Delaware Basin case history describes a bradenhead cementing method that improves zonal isolation and top of cement (TOC). Common solutions for cementing depleted formations include stage tools, low-density slurries, and reverse circulation. For this bradenhead method, cement is pumped through the wellhead valves and down the annulus to a target loss zone. Field data, laboratory data, and the engineering model support the improvement bradenhead cementing provided across depleted formations.

The depleted Brushy Canyon Formation serves as an injection interval for a two-stage bradenhead cement job. This approach isolates formations below the Brushy Canyon with a conventional first stage, while achieving TOC with the second stage pumped down the annulus. Fracture gradients of the injection interval and casing shoe constrain the cement design. To achieve adequate cement placement, the design phase includes the pressure calculations required to start flow and injection for the bradenhead stage. Reactive spacers are utilized to prevent annulus fluid level drop in extreme cases. A benchmarked cement bond log (CBL) quantifies the results and validates this unconventional cementing method.

More than 50 two-stage bradenhead cement jobs were executed with a TOC success rate of 100% in intermediate and production hole applications. CBL data obtained after cementing the intermediate casing confirm the two-stage bradenhead as a placement method. In areas constrained by casing shoe pressures, CBL data identified potential areas of shallow injection. These data resulted in a modification of the fluids pumped. Use of these re-engineered fluids reduced injection initiation pressures and improved cement bonding across salt and anhydrite formations. Cementing costs were reduced by eliminating stage tools, annular casing packers, and low-density cement slurries. Pumping the bradenhead job offline (off the rig’s critical path) reduces cost further. These features support bradenhead cementing as an effective solution for wellbore sections with a potential injection zone.

The regulatory requirement to place cement above depleted formations resulted in many innovative cementing methods. Stage tools, low-density slurries, and reverse circulation are attempts to avoid formation breakdown, but these methods increase cost and have limited reliability and integrity. Bradenhead cementing takes advantage of the depleted interval to aid in cement placement. Although counterintuitive, bradenhead cementing has proved to be a cost-effective solution that improves zonal isolation and eliminates integrity risks associated with stage tool failures.
Not all cities are the same: variation in animal phenotypes across cities within urban ecology studies
Authors: delBarco-Trillo Javier , Putman Breanna J.
Published: October 2022

The sustained expansion of urban environments has been paralleled by an increase in the number of studies investigating the phenotypic changes of animals driven by urbanization. Most of these studies have been confined to only one urban center. However, as the types and strength of anthropogenic stressors differ across cities, a generalizable understanding of the effects of urbanization on urban-dwelling species can only be reached by comparing the responses of urban populations from the same species across more than one city. We conducted phylogenetic meta-analyses on data for animal species (including both invertebrates and vertebrates) for which measures about any morphological, physiological, or behavioral trait were reported for two or more cities. We found that morphological, physiological and behavioral traits of urban animals all differ similarly across cities, and that such phenotypic differences across cities increase as the more cities were investigated in any given study. We also found support for phenotypic differences across cities being more pronounced as the farther away cities are from each other. Our results clearly indicate that separate urban populations of the same species can diverge phenotypically, and support previous pleas from many researchers to conduct urban studies across several urban populations. We particularly recommend that future studies choose cities in different biomes, as urban adaptations may differ substantially in cities sited in different ecological matrices. Ultimately, a generalized knowledge about how organisms are affected by urbanization will only be possible when comprehensive biological patterns are similarly studied across separate and distinct cities.