bluuebunny/crossref_metadata_2025 huggingface dataset:
IDENTIFIKASI CEMARAN LOGAM BERAT PADA TEMPE DI PENGRAJIN TEMPE X DAN Y KOTA BENGKULU
Authors: Risalatuzain Eldania , Yosephin Betty , Okfrianti Yenni
Published: November 2019

Proses fermentasi tempe, higiene memegang peran penting untuk menghasilkan produk yang sehat. Industri tempe Indonesia yang telah menerapkan prinsip higiene sekitar 5%. Cemaran logam berat pada makanan perlu diketahui agar terwujudnya keterjaminan dan keamanan makanan. Logam dapat menyebabkan keracunan (toksisitas) dan ini sangat berbahaya bagi makhluk hidup (hewan dan manusia), logam tersebut meliputi timbal (Pb), merkuri (Hg), Arsen (As), dan kadmium (Cd). Tujuan penelitian ini untuk mengetahui cemaran logam berat pada tempe di pengrajin tempe X dan Y Kota Bengkulu. Desain penelitian ini adalah deskriptif kualitatif dengan pendekatan observasional menggunakan pemeriksaan laboratorium pada tempe di pengrajin tempe X dan Y Kota Bengkulu. Penelitian yang dilakukan terdapat 4 uji di laboratorium yaitu kadmium (Cd), timbal, (Pb), timah (Sn), dan merkuri (Hg). Hasil penelitian ini menunjukan bahwa terdapat kandungan logam berat pada tempe di pengrajin X dan Y tetapi masih dibawah batas maksimum dari syarat mutu tempe menurut BSN 2015. Kesimpulan penelitian ini bahwa kandungan logam berat timbal, cadmium, timah, dan merkuri pada pengrajin tempe X dan Y Kota Bengkulu dalam batas aman dari syarat mutu tempe menurut BSN 2015. Saran penelitian ini dapat mengidentifikasi kandungan tempe dari syarat mutu tempe lainnya.
KONSUMSI TABLET FE DAN PENGETAHUAN BERHUBUNGAN DENGAN ANEMIA PADA IBU HAMIL TRIMESTER III
Authors: Sari Eka Ratna , Andriani Lusi , Kurniawati PS.
Published: November 2019

Anemia in pregnancy is a condition of pregnant woman with hemoglobin (Hb) <11 gr% in the first and third trimesters while in the second trimester hemoglobin level <10,5 gr%. World Health Organization (WHO) in 2012, reported that the prevalence of anemia in pregnant women in the world ranges an average of 14%, in industrialized countries 56% and in developing countries between 35% -75%. This study aims to determined the factors of the occurrence of anemia in third trimester pregnant women in Kampung Melayu sub-district Bengkulu City 2017. This research uses Analytical Survey design with Cross Sectional Approach. Population in this research is third trimester pregnant woman in Kampung Melayu sub-district as many as 106 people, using sample total sampling technique. The analysis used Chi square test with significance level p <0,05.The results of this study indicate that there is a relationship between adherence of Fe (p = 0,000) and knowledge (p = 0,000) with anemia occurrence in third trimester pregnant women, no relationship between age (p = 0,346), parity (p = 0,949) , Education (p = 0.198), occupation (p = 1,000) with anemia and the most dominant factor with anemia was the consumption of Fe tablet (OR = 78,803). Health workers are expected to provide routine counseling on the causes, symptoms, and effects of anemia for pregnant women and screening anemia by checking Hb at least twice during pregnancy.
FAKTOR- FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PREEKLAMPSI BERAT (PEB)
Authors: Novrianti Silpia , Rachmawati Rachmawati , Yuniarti Yuniarti
Published: November 2019

Severe preeclampsia (PEB) is still one of the causes of maternal morbidity and mortality if not adequately treated. There are many things that affect the occurrence of PEB, some of which are maternal age, parity, gestational age and education. The high incidence of PEB in the 2016. Yunus Bengkulu District Hospital Obstetric Room in 2016. The purpose of this study was to determine the factors that influence the incidence of PEB in Yunus Bengkulu Public Hospital in 2016. The design of this study was using case control, with a maternal population 1070 people in 2016 with a sample of 162 people. The analysis was carried out univariately and bivariately using Chi-Square test while multivariate analysis used Logistic Regression test. The results showed that there was a relationship between age, parity, gestational age and education with the incidence of PEB. The results of multivariate analysis showed that education had the most influential relationship to the incidence of severe preeclampsia.
PEMBERIAN ASI BERPENGARUH TERHADAP RESPON NYERI BAYI PADA PENYUNTIKAN IMUNISASI PENTAVALEN
Authors: Atikah Atikah , Heryati Kosma , Eliana Eliana
Published: November 2019

Imunisasi pada bayi merupakan tindakan yang dapat menimbulkan trauma karena hal tersebut dapat menyebabkan nyeri. Salah satu teknik menejemen nyeri non-farmakologi adalah dengan pemberian ASI. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas pemberian ASI terhadap penurunan respon nyeri pada bayi yang dilakukan imunisasi Pentavalen. Penelitian menggunakan metode Quasi Eksperimen dengan static group comparation dan teknik pengambilan sampel menggunakan consecutive sampling, jumlah sampel didapatkan 54 responden. Penelitian ini dilakukan di Puskesmas Sawah Lebar Kota Bengkulu pada tanggal 11 September – 10 Oktober 2017. Analisis perbedaan respon nyeri menggunakan Independent Sample t-Test. Hasil penelitian ini menunjukkan rata-rata respon nyeri pada bayi pada kelompok intervensi adalah 3,89. Sedangkan pada kelompok kontrol rata-rata tingkat nyerinya adalah 7.63. Hasil analisis bivariat menunjukkan ada perbedaan rata-rata respon nyeri pada bayi yang diberikan ASI (intervensi) dengan bayi yang diberikan terapi sentuhan (kontrol) pada saat dilakukan penyuntikan imunisasi Pentavalen sebesar 3,74 (p=0,000). Diharapkan bagi Puskesmas khususnya petugas imunisasi dapat menerapkan prinsip menurunkan respon nyeri pada bayi yang diimunisasi yaitu dengan melakukan intervensi pemberian ASI sebelum dan sesudah dilakukan penyuntikkan imunisasi pada bayi yang merupakan salah satu Asuhan Sayang Bayi.
PEMBERIAN ES KRIM UBI JALAR UNGU BERPENGARUH TERHADAP KADAR KOLESTEROL TOTAL DAN TEKANAN DARAH PASIEN HIPERKOLESTEROLEMIA
Authors: Arisetia Dwita , Yuliantini Emy , Kusdalinah Kusdalinah
Published: November 2019

Hiperkolesterolemia merupakan salah satu penyebab dari penyakit kardiovaskular. Studi epidemiologi membuktikan ada hubungan antara peningkatan kadar kolesterol total, khususnya kolesterol LDL dengan kejadian PJK, penurunan kadar kolesterol dapat menurunkan resiko kejadian kardiovaskular dan kolesterol yang tidak normal meningkatkan resiko hipertensi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian es krim ubi jalar ungu terhadap kadar kolesterol total dan tekanan darah pada pasien hiperkolesterolemia.Desain penelitian ini adalah Pra-eksperimental dengan metode one group pretest-posttest. Sampel dalam penelitian ini sebanyak 30 orang  yang memenuhi kriteria inklusi. Intervensi yang diberikan adalah pemberian es krim ubi jalar ungu sebanyak 60 gr (1 cup) per hari selama 28 hari. Data yang didapat dianalisa menggunakan uji t-test dependen. Pemberian es krim ubi jalar ungu berpengaruh secara signifikan terhadap kadar kolesterol total dan tekanan darah dengan nilai p < 0,05. Ada pengaruh pemberian es krim ubi jalar ungu terhadap kadar kolesterol total dan tekanan darah pada pasien hiperkolesterolemia di Puskesmas Basuki Rahmat.
TEKNIK RELAKSASI GENGGAM JARI OLEH SUAMI BERPENGARUH TERHADAP NYERI POST OPERASI SECTIO CAESAREA
Authors: Saputra Denny , Asmawati Asmawati , Septiyanti Septiyanti
Published: November 2019

Nyeri pasca bedah SC akan menimbulkan reaksi fisik dan psikologi pada ibu postpartum seperti  gangguan mobilisasi, malas beraktifitas, sulit tidur, tidak nafsu makan, tidak mau merawat bayi sehingga diperlukan cara untuk mengontrol nyeri agar dapat beradaptasi dengan nyeri post operasi  sectio  caesarea. Tujuan penelitian ini adalah mengetahui pengaruh teknik relaksasi genggam jari yang dilakukan oleh suami terhadap nyeri post operasi Sectio Caesarea (SC).
Desain penelitian ini adalah quasi eksperimen dengan pretest-posttest with control group Teknik pengambilan sampel menggunakan consequtive sampling. Jumlah responden 58 orang terdiri dari 29 orang kelompok kontrol dan 29 kelompok intervensi alat ukur yang digunakan menggunakan NRS (numerical rating scale).
Hasil  penelitian menunjukkan bahwa rata-rata nyeri sebelum intervensi kelompok kontrol 5 skala nyeri dan kelompok intervensi 5,5. Setelah intervensi skala nyeri pada kelompok kontrol 4,1 dan kelompok intervensi 3,4. Ada perbedaan nyeri sebelum dan sesudah dilakukan intervensi genggam jari yang dilakukan oleh suami (p-value = 0,000)
POLA KONSUMSI LEMAK DAN RLPP BERHUBUNGAN DENGAN KEJADIAN PENYAKIT JANTUNG KORONER
Authors: Pabela Igha Aprilesika , Krisnasary Arie , Haya Miratul
Published: November 2019

Tujuan penelitian untuk mengetahui hubungan pola konsumsi lemak (jenuh dan tak jenuh) dan RLPP dengan kejadian penyakit jantung koroner di poli rawat jalan RSUD M. Yunus Kota Bengkulu Tahun 2017. Penelitian ini merupakan survey analitik dengan pendekatan retrospective, desain case control. Lokasi penelitian di poli rawat jalan RSUD M. Yunus kota Bengkulu. Penelitian dilaksanakan tanggal 8 Mei – 8 Juni 2016. Sampel adalah pasien PJK yang berobat di poli rawat jalan RSUD M. Yunus Kota Bengkulu sebanyak 74 sampel. dilakukan dengan teknik purposive sampling. Data asupan lemak jenuh dan tak jenuh pasien, diperoleh melalui form food frequency questioner (FFQ) dan data RLPP, usia, jenis kelamin, tekanan darah, kebiasaan merokok diperoleh melalui kuesioner. Data yang diperoleh dianalisis menggunakan univariat dan bivariat. Hampir seluruh pasien sering mengkonsumsi lemak jenuh dan tak jenuh. Hampir seluruh pasien dengan RLPP berstatus gizi obesitas. Ada hubungan yang signifikan antara pola konsumsi lemak (jenuh dan tak jenuh) (p=0,0,022), RLPP (p=0,014), jenis kelamin (p=0,0005), kebiasaan merokok (p=0,0005) dengan kejadian penyakit jantung koroner. Tidak ada hubungan antara usia (p=0,056) dan tekanan darah (p=0,10) dengan kejadian penyakit jantung koroner.
Ada hubungan antara pola konsumsi lemak (jenuh dan tak jenuh), RLPP dengan kejadian penyakit jantung koroner di poli rawat jalan RSUD M. Yunus Kota Bengkulu Tahun 2017. Perlunya peran aktif keluarga terkait motivasi dengan cara mengingatkan pola makan pasien penyakit jantung koroner.
National-patriotic education of future teachers of musical art in the study of the
disciplines of the conductor-choral cycle (on the example of the revival of the choral heritage of A. Wedel abroad)
Authors: Parfentyeva Irina
Published: November 2019

The article deals with the problems of the national-patriotic education of future teachers of musical art by means of choral art on the example of one of the outstanding representatives of the Ukrainian composer and choirmaster school – Artemy Lukyanovich Vedel. The stages of knowledge of the choral heritage of the Ukrainian
composer of the late eighteenth and early nineteenth centuries in Western Europe and America of the twentieth century are considered. Sources from periodicals allow us to analyze various forms of perception of his works by a foreign listener during concert performances. Named the national choir, Ukrainian and foreign performers, who
were direct popularizers of the artist’s creativity. The distribution of A. Vedel’s choral heritage in the countries of Western Europe and America of the twentieth century had its own definite place. The problem of popularizing the choral heritage of the outstanding Ukrainian composer Artemii Lukyanovich Vedel is not sufficiently covered in
modern scientific research. Domestic educators and culturologists pay more attention to revealing the secrets of biography, outlook and search of little-known works of the composer, therefore the question of widespread distribution of his musical work is now relevant, which helps to highlight the bright personality of the artist. The source
of our searches is based on the materials of publications of the national periodicals of the twentieth century.
These are, first and foremost, magazine and newspaper articles related to concert performances by well-known domestic choral groups and individual performers of the last century. Available factual materials allow us to conclude that despite all the prohibition on singing the works of this composer in the 19th and the first half of the
20th century, his art proved his vitality in concert performance by choir collectives, in the pedagogical repertoire of educational choir collectives, which was confirmed by modern practice. national musical pedagogy. This topic, with all its obvious features, has a prospect of development in various areas of musical and pedagogical research.
PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF DYSGLICEMIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AT THE STAGE OF DECOMPENSATION OF CHRONIC CARDIAC FAILURE
Authors: Ishekova M. Yu. , Dvoryashina I. V. , Kholmatova K. K. , Grjibovski A. M.
Published: November 2019

The aim was to study the prevalence of dysglycemia and glycemic variability (GV) during hospitalization for chronic heart failure (CHF) decompensation and their effect on four-years survival. Methods: A retrospective analysis of the hospital records of 279 patients with type 2 diabetes mellitus (DM), hospitalized with CHF decompensation to the First City Clinical Hospital in Arkhangelsk was performed. Mann - Whitney tests were used for numeric variables. Simple and multiple logistic regression analyses were used to determine the effect of glycemia at admission, GV indicators on the early and long-term prognosis. Results: Median blood glucose at hospitalization was 8.80 (6.74; 11.04) mmol/l. Off-target glycemia was observed in 245 (87.8 %) patients. More than half of the measured tests during hospitalization had glycemic values beyond the recommended levels for the hospitalization period (82.6 %). In patients who died in the long-term period (n = 64, 28.1 %), hyperglycemia of more than 10.0 mmol/l was observed in 43.8 % of the measured tests during hospitalization, in 18.3 % - hyperglycemia from 7.8 to 10.0 mmol/l. Patients who died in the long-term period had higher indices of GV in comparison with the survivors (p = 0.004 for glycemic level variation, p = 0.008 for standard deviation and p = 0.001 for variation coefficient). High GV was associated (OR: 1.943; CI 1.013-3.725, p = 0.046) with the outcome, regardless of gender, manifestations of heart failure and renal function. Conclusions. Altogether, 87.8 % of patients had dysglycemia during the period of hospitalization. High GV during hospitalization was observed in 50.2 % of patients. High GV during hospitalization is an independent risk factor for for-years mortality
Ivabradine does not Impair Anxiety-Like Behavior and Memory in Both Healthy and L-NAME-Induced Hypertensive Rats
Authors: KRAJCIROVICOVA K. , AZIRIOVA S. , BAKA T. , REPOVA K. , ADAMCOVA M. , PAULIS L. , SIMKO F.
Published: November 2019

Cardiovascular pathologies are frequently associated with anxiety and other behavioral disturbances. Ivabradine, an inhibitor of the hyperpolarization-activated cyclic nucleotide-gated channels in the sinoatrial node, decreases heart rate and provides cardiovascular protection. Although ivabradine is increasingly used in cardiovascular medicine, the data on its behavioral effects are lacking. The aim of this work was to show ivabradine’s potential effect on behavior in healthy and hypertensive rats. After a four-week treatment period, systolic blood pressure was increased in the N(G)-nitro-L-arginine methyl ester (L-NAME)-group and ivabradine significantly reduced it. Furthermore, it reduced the heart rate in both the control and L-NAME-group. In the control group, ivabradine enhanced the time spent in and transition to the open arms of the elevated plus maze test (EPM). In the L-NAME-group, ivabradine does not show a significant effect on the time spent in the EPM open arms and the number of transitions into them. Furthermore, ivabradine has no impact on cognitive function in both control and L-NAME groups. We conclude that ivabradine showed no undesirable effects on anxiety, locomotion or learning; in fact, some of these parameters were even improved. For the first time it has been shown that ivabradine is a safe cardiovascular drug regarding its effect on psycho-behavioral manifestations.
Information Domain Analysis of Respiratory Sinus Arrhythmia Mechanisms
Authors: KROHOVA J. , CZIPPELOVA B. , TURIANIKOVA Z. , LAZAROVA Z. , WISZT R. , JAVORKA M. , FAES L.
Published: November 2019

Ventilation related heart rate oscillations – respiratory sinus arrhythmia (RSA) – originate in human from several mechanisms. Two most important of them – the central mechanism (direct communication between respiratory and cardiomotor centers), and the peripheral mechanism (ventilation-associated blood pressure changes transferred to heart rate via baroreflex) have been described in previous studies. The major aim of this study was to compare the importance of these mechanisms in the generation of RSA non-invasively during various states by quantifying the strength of the directed interactions between heart rate, systolic blood pressure and respiratory volume signals. Seventy-eight healthy volunteers (32 male, age range: 16.02-25.77 years, median age: 18.57 years) participated in this study. The strength of mutual interconnections among the spontaneous beat-to-beat oscillations of systolic blood pressure (SBP), R-R interval (RR signal) and respiration (volume changes – RESP signal) was quantified during supine rest, orthostatic challenge (head-up tilt, HUT) and cognitive load (mental arithmetics, MA) using bivariate and trivariate measures of cardio-respiratory information transfer to separate baroreflex and nonbaroreflex (central) mechanisms. Our results indicate that both basic mechanisms take part in RSA generation in the intact cardiorespiratory control of human subjects. During orthostatic and mental challenges baroreflex based peripheral mechanism becomes more important.
ANALISIS KETERAMPILAN DASAR MENGAJAR GURU DALAM MELAKSANAKAN PEMBELAJARAN DI SEKOLAH DASAR
Authors: Bastian Bastian
Published: November 2019

This research was conducted at SD Neger 022 Pulau Baru Kopah, Sentajo Raya District. The purpose of this study was to find out how the basic teaching skills of teachers at SDN 022 Pulau Baru Kopah. The subjects in this study were 15 class teachers, consisting of 4 male teachers and 11 female teachers. Judging from the problems discussed about describing the basic skills of teaching teachers in implementing learning, this study belongs to a descriptive quantitative study. Descriptive quantitative research is a method that examines a group of people, an object, a system of thought or an event in the present. The results showed that the basic teaching skills of teachers at SD Negeri 022 Pulau Baru Kopah obtained an average grade of 76.9 in the good category. Broadly speaking, it can be concluded that the use of basic teaching skills of teachers in the implementation of learning has been classified as good.
Ru-containing Catalysts for Liquid-phase Fischer-Tropsch Synthesis
Authors: Markova M. , Stepacheva A. , Gavrilenko A. , Petukhova I.
Published: November 2019

The search for new stable and active catalysts of Fischer-Tropsch synthesis is one of the key directions for production of liquid fuels from alternative raw materials. Stabilization of the active phase is the main task in the development of catalysts for hydrogenation of CO into liquid fuels. This problem can be solved by choosing the optimal support, as well as the synthesis method. This work is devoted to the development of new polymer mono– and bimetallic Ru-containing catalysts for liquid phase Fischer-Tropsch synthesis. It is shown that the use of 1% Ru-HPS and 10% Co — 1% Ru-HPS allows to obtain a high yield of gasoline hydrocarbons (more than 70%), providing a high conversion of CO (up to 23%). The selected polymer-based systems showed high stability in the Fischer-Tropsch synthesis process.
The Process of Catalytic Hydrocondensation of Sugars and Amines
Authors: Mikhailov S. , Sulman A. , Matveeva V. , Doluda V.
Published: November 2019

N-methylglucamine (MGA, trade name meglumin) is a derivative of D-sorbitol, widely used in medical chemistry to highly solubilize and stabilize biologically active compounds used in cardiovascular diseases, which have antiepileptic, analgesic, antimicrobial, antibacterial, antitumor and many other actions. N-methylglucamine promotes the transition to personalized medicine, high-tech healthcare and health-saving technologies, including through the rational use of drugs (primarily antibacterial ones). This technology may be in demand by pharmaceutical companies and the food industry.
Production of Zol-Gel Pasta in the Complex System ВаСl2-SrCl2-Sb2О3 Based on Lemonic Acid and Н2О at Temperature Interval 40-42 °С
Authors: Atambekova A. , Tashpolotov Y. , Ysmanov E.
Published: November 2019

The article investigated the preparation of sol-gel paste from many component substances barium chloride (BaCl2), strontium chloride (SrCl2), antimony trioxide (Sb2O3), citric acid in a liquid medium by the complexometric (chelate) method. During the reaction, the pH of the medium was 5.5 units, temperature conditions 40–42 °C. For efficient complex formation, an electric mixer was used. The ratio of multicomponent substances was according to the following formula BaIx ∙ SrIx ∙ SbIx ∙ CAIx (where X = I:I:I:I). This reaction was studied, complexes with metal ions. Thus, the sol-gel process includes hydrolysis at temperature conditions, and the mechanical effects of the latter processes occur during further polymerization and a viscous resin (gel) is formed. A homogeneous white paste is obtained, which is nanosubstances.
SIMULASI DAN EKSPERIMEN KONTROL AUTOMATIC TURRET GUN
Authors: Tamara Mohamad Nasyir , Pramujati Bambang , Nurhadi Hendro , Pitowarno Endra
Published: November 2019

This research presented Active Force Control (AFC) as a control method which is applied to Automatic Turret gun (ATG) in ground combat vehicles This method compares the reference force conducted by actuator with actual force of the mechanical systems that arise due to disturbances. The advantage of AFC method is its ability to handle disturbances effectively without complicated mathematical calculations. The AFC method uses Crude Approximation (CA) in the internal loop controller AFC as inertia matrix estimator as an important part in the control loop.  Simulation without load on the azimuth movement shows PID controller produces the best precision with MSE of 0 degrees while RACAFC and RAC method provide MSE 0.267 degrees. In simulation on the elevation movement, the RAC method showed the best results with an estimated MSE of the targets shot of 2.42 degrees, while the PID and RACAFC method are 2.5 and 2.46 degrees. When simulation is conducted with additional load RACAFC method gives the best precision with a MSE of 0.267 and 2:46 degrees, while the PID method was 4.24 and the 10.52 degrees. RAC method produces MSE of 0.7 and 2.87 degrees. With the added load the performance of PID controller decreases. In the experiment on the constructed rig, RAC and RACAFC scheme produce smoother movement trajectory and minimum oscillation compared to the PID controller. In loaded conditions these methods are able to maintain their performance. However, these three methods can still achieve a reference point with or without load in the end of travel time
INSTALASI ESP (ELECTRIC SUBMERSIBLE PUMP) SISTEM TANDEM PADA SUMUR MINYAK DENGAN VARIABLE SPEED DRIVE
Authors: Sucipto Hari , Wiwaha Sigit Setya , Ridzki Imron
Published: November 2019

When the pressure of an oil well is not too large to do Natural Flow, Artificial Lift is one of the methods that can be used to replace it, artificial lift usually using ESP (Electric Submersible Pump). ESP oil pump in petroleum is equipped with VSD (Variable Speed Drive) component to adjust motor speed as softstarter and oil rate regulator and as pump motor protection. For ESP construction with a motor tandem system installed on wells with different characteristics and depths that are different from ESP single motors. However, submersible pumps are augmented by increasing the number of pump stages according to the depth of the well by coupling, submersible electric motors can be mechanically coupled and electrically on a spindle between upper motor and center motor.
KAJIAN IMPLEMENTASI PIRANTI THERMOELECTRIC (PELTIER) SEBAGAI SISTEM PENGATUR SUHU THERMOS PENYIMPAN SPERMATOZOA
Authors: Singgih Hariyadi , Subiyantoro Subiyantoro , Siswoko Siswoko
Published: November 2019

One alternative application of technology in the field of animal reproduction is by artificial insemination technology (IB). Artificial Insemination Process (IB) is a technique for inserting spermatozoa or semen which has been melted and processed first into the female genital tract. To obtain good quality cement, cow sperm preservation by dilution and followed by cooling to 5 ° C (chilling process). The chilling process with cement storage using 5 ° C will keep the cement life of 7 to 10 days. For this fulfillment, the Thermos box prototype is designed as a spermatozoa storage device to ensure good cement quality. The research method is design of prototype tool using Thermoelectric TEC (peltier) type device TEC1-12706T200. And use the LM35 temperature sensor device to detect the temperature in the box. Thermos. This study examines the efficiency of time required by the system when it reaches 5.0 ° C. and influential parameters in accelerating the temperature performance of 5.0 ° C. The readable temperature of the LM35 sensor will be displayed on a 16x2 LCD monitor. Data processing system using Arduino Microcontroller. Measurement result and performance assessment of Thermoelectric TEC (peltier) device type TEC1-12706T200 when it reaches maximum working temperature 5,5 º C within 8 hours. has an error of 2.5%. which depends on the size of the power supply (Current) electricity.
PEMANTAUAN PERUBAHAN SUHU TERHADAP PENGONTROLAN PADA HEAT EXCHANGER DENGAN SENSOR PT100 BERBASIS
Authors: Pratama Yufinda Rahmatika , Parastiwi Andriani , Amri Syaiful Ulil
Published: November 2019

Heat exchanger berfungsi mentransfer energi panas antara 2 fluida, atauantar partikel padat dengan fluida yang memiliki beda suhu dan terjadikontak panas secara kontinyu. Pada penelitian ini, input Heat Exchangeradalah udara dengan tekanan bervariasi yang dipanaskan dan dikontrolsehingga output Heat Exchanger adalah udara panas dengan suhu dijaga200°C. Pemantauan perubahan suhu heat exchanger berfungsi untukmemantau hasil pengaturan suhu sehingga output tetap pada seting suhutertentu dan memantau perubahan suhu terhadap waktu pada proseskonversi panas pada Heat Exchanger yang dihasilkan. Sensor suhu yangdigunakan adalah PT100 dengan Raspberry Pi 3 sebagaimikrokontrolernya dan pengontrolan suhu yang digunakan adalahkontrol dengan kontrol PID. Kontrol PID bertujuan untuk menstabilkansuhu output Heat Exchanger 200°C dengan tekanan udara input berbedadengan cara mengatur bukaan motor servo yang terpasang di pemanaspada heat exhanger. Tekanan udara input 3 bar mencapai suhu 200°C dimenit ke 8 lebih cepat daripada tekanan udara input 5 bar yangmencapai suhu 200°C pada menit ke 9,5 menit. Dengan berbasisinternet, maka pemantauan perubahan suhu dapat dipakai untuk integrasidalam sistem yang lebih luas dalam plant industri.
STABILISASI TEGANGAN KELUARAN BUCK CONVERTER DENGAN METODE FUZZY LOGIC CONTROLLER
Authors: Melfazen Oktriza
Published: November 2019

Buck converter idealnya mempunyai keluaran yang stabil, pemanfaatandaya rendah, mudah untuk diatur, antarmuka yang mudah dengan pirantiyang lain, ketahanan yang lebih tinggi terhadap perubahan kondisi alam.Beberapa teknik dikembangkan untuk memenuhi parameter buckconverter. Solusi paling logis untuk digunakan pada sistem ini adalahmetode kontrol digital.Penelitian ini menelaah uji performansi terhadap stabilitas tegangankeluaran buck converter yang dikontrol dengan Logika Fuzzy metodeMamdani. Rangkaian sistem terdiri dari sumber tegangan DC variable,sensor tegangan dan Buck Converter dengan beban resistif sebagaimasukan, mikrokontroler ATMega 8535 sebagai subsistem kontroldengan metode logika fuzzy dan LCD sebagai penampil keluaran.Dengan fungsi keanggotaan error, delta error dan keanggotaan keluaranmasing-masing sebanyak 5 bagian serta metode defuzzifikasi center ofgrafity (COG), didapat hasil rerata error 0,29% pada variable masukan18V–20V dan setpoint keluaran 15V, rise time (tr) = 0,14s ; settling time(ts) = 3,4s ; maximum over shoot (%OS) = 2,6 dan error steady state(ess) = 0,3.
PEMBANGUNAN LINK PENELUSURAN KEBUTUHAN FUNGSIONAL DAN METHOD PADA KODE SUMBER DENGAN METODE PENGAMBILAN INFORMASI
Authors: Pramono Djoko , Setiawan Nanang Yudi
Published: November 2019

Link penelusuran antara dokumen kebutuhan dan kode sumber sangatmembantu dalam proses pengembangan dan pemeliharaan perangkatlunak. Dalam proses pemeliharaan perangkat lunak, pengembangmelakukan perubahan pada kode sumber tetapi sering tidakmemperbarui dokumen yang menyertainya. Adanya link penelusuranantara dokumen kebutuhan dengan kode sumber diharapkanmeningkatkan kecepatan menemukan bagian kode sumber yang perludiubah ketika ada perubahan kebutuhan.Dalam penelitian ini dilakukan evaluasi terhadap dua metodepengambilan informasi (information retrieval/IR) yaitu LSA(LatentSemantic Analysis) dan LDA(Latent Dirichlet Allocation) untukmenemukan link antara kebutuhan fungsional dan method dalam kodesumber program. LSA merupakan sebuah metode yang memanfaatkanmodel statistik matematis untuk menganalisa struktur semantik suatuteks. LDA adalah model probabilistik generatif untuk sekelompok datadiskrit seperti corpus. Langkah pertama adalah membentuk kumpulankata(bag of words) dari method dalam kode sumber dan dokumenkebutuhan fungsional. Langkah berikutnya adalah menghitung nilaikedekatan semantic menggunakan cosine similarity.Pengujian dilakukan menggunakan kedua metode pada dataset yangterdiri dari kebutuhan fungsional dan kode sumber ITrust dan GanttProject. Kemudian dihitung nilai precision dan recall. Nilai f-measuresebesar 0,26 diperoleh pada recall sebesar 0,23 dan precission 0,305pada pengujian menggunakan metode LDA. Metode LDA memberikanhasil lebih baik daripada LSA namun nilai precision dan recall yangdihasilkan dari kedua metode tersebut masih rendah .
OPTIMALISASI RESISTANSI FEEDBACK DAN RESISTANSI INPUT PADA PENGUAT INVERTING UNTUK PENGKONDISI SINYAL
Authors: Mandayatma Eka
Published: November 2019

Penguatan rangkaian penguat inverting dengan Op Amp ditentukan oleh nilai Resistansi Feedback (Rf) dan Resistansi Input (Rin) dimana penguatan merupakan perbandingan antara Rf dan Rin. Biasanya salah satu nilai (Rf atau Rin) diambil secara bebas. Secara teoritis formula tersebut memperbolehkan memberikan nilai Rf dan Rin berapapun asalkan memenuhi syarat kebutuhan penguatan (Av). Penentuan nilai yang bebas (berapapun) ini sering membingungkan karena secara teori semua nilai bisa diterapkan namun secara praktik dilapangan tidak semua nilai bisa memberikan hasil yang diharapkan. Untuk menghilangkan kebingungan dalam memilih nilai Rf dan Rin yang memenuhi maka perlu ditentukan satu nilai Optimal. Dengan penentuan Rf dan Rin optimal maka dalam satu perencanaan tidak ada nilai yang berbeda-beda dan dipastikan rangkaian penguat bekerja sesuai dengan fungsinya. Nilai Rf dan Rin optimal ditentukan oleh Resistansi Input deferensial (Rid) dan Resistansi Output (Ro) dari IC op Amp yang digunakan dan tergantung pula dengan fungsi alih (penguatan) dari Rangkaian yang direncanakan. Dengan nilai Rf optimal maka rangkaian penguat bisa bekerja dengan baik dan tidak terjadi perbedaan dalam pemilihan resistansi feedback maupun resistansi input.

Strengthening the inverting amplifier circuit with the Op Amp is determined by the Feedback Resistance (Rf) and Input Resistance (Rin) where the gain is a comparison between Rf and Rin . Usually one value (Rf or Rin) is taken freely. Theoretically the formula allows giving any value of Rf and Rin as long as it meets the requirements for reinforcement requirements (Av). Determination of free value (whatever) is often confusing because in theory all values can be applied but practically in the field not all values can provide the expected results. To eliminate the confusion in choosing the value of Rf and Rin that meets the need to be determined one Optimal value. With the determination of Rf and Rin optimally in one plan there are no different values and it is certain that the amplifier circuit works according to its function. The optimal Rf and Rin values are determined by the Differential Input (Rid) Resistance and Output Resistance (Ro) of the IC op Amp used and depend also on the transfer function (gain) of the planned Circuit. With the optimal Rf value the amplifier circuit can work properly and there is no difference in the selection of feedback resistance or input resistance.
APLIKASI KONTROL PID PADA PROSES PENGOLAHAN AIR LAUT MENGGUNAKAN METODE REVERSE OSMOSIS BERBASIS DCS
Authors: Singgih Hariyadi Singgih , Subiyantoro Subiyantoro , Siswoko Siswoko
Published: November 2019

Metode pemurnian air laut menggunakan pengaturan kecepatan motor dalam proses reverse osmosis sangat dibutuhkan, dikarenakan proses penyaringan dalam membran reverse osmosis membutuhkan tekanan yang sesuai dengan kemampuan membran. Selain itu juga dibutuhkan kontrol ketinggian air untuk mengotomatisasi tangki yang telah penuh dan mempertahankan ketinggian air.

Solusi untuk mengurangi permasalahan ini digunakan DCS yang berfungsi untuk memonitor dan mengontrol plant dari jarak jauh, Metode kontrol yang digunakan pada DCS untuk menstabilkan set point menggunakan metode kontrol PID Ziegler-Nichols. Dalam penelitian ini dirancang mini plant kontrol ketinggian air dan tekanan menggunakan metode PID Ziegler-Nichols yang diimplementasikan pada DCS-PCS7. Sensor yang digunakan untuk ketinggian air adalah HC-SR04, dan untuk sensor tekanan menggunakan pressure transmitter.

Dengan aplikasi kontrol PID diperoleh kestabilan set point dengan parameter kontrol ketinggian air : Kp=134.4, Ti=0 dan Td=1. Waktu untuk mencapai set point 120 detik dan  error steady state sebesar 0.94% tanpa gangguan. Untuk parameter Kontrol tekanan air sebesar: Kp=3, Ti=0 dan Td=1.375 dan Delay time = 4s, Rise time = 7s, Settling time = 25s, Osilasi output PID rendah, Error steady state = 1.03% tanpa gangguan.
DISAIN PERANCANGAN ALAT UJI IC TTL / CMOS UNTUK PENUNJANG LABORATORIUM ELEKTRONIKA DIGITAL
Authors: Siswoko Siswoko , Singgih Hariyadi , Komarudin A.
Published: November 2019

Bentuk IC TTL dan CMOS yang kecil dan memiliki jumlah pin bervariasi membuat orang kesulitan untuk melakukan pengujian kondisi IC TTL dan CMOS secara cepat. Beberapa cara pengujian IC TTL dan CMOS secara manual yakni menggunakan protoboard. Akan tetapi hal tersebut membutuhkan waktu yang cukup lama. Dari permasalahan tersebut, dibutuhkan adanya alat uji yang dapat mempermudah pengguna untuk mengetahui kondisi IC TTL dan CMOS sebelum digunakan. Alat uji IC digital ini dibuat untuk menguji apakah IC yang digunakan dalam keadaan baik atau rusak. Karena jenis IC TTL dan CMOS yang akan diujikan lebih dari satu, maka dalam penelitian ini digunakan keypad sebagai alat untuk menyeleksi IC yang akan diujikan. Keunggulan dari pembuatan alat uji IC ini adalah penyusun dan mengkombinasikan rangkaian dengan menggunakan mikrokontroler AVR Atmega 644 dengan hasil output dapat dilihat pada tampilan di LCD, berupa kondisi dari IC tersebut. Alat uji IC TTL seri 74xxx dan CMOS seri 40xx ini dapat digunakan untuk menguji 100 IC dengan total kesalahan 0%.
The Relationship Between Mother Visit to Maternal and Child Health Centre (MCHC) and Timely of Giving Complementary Foods in Timur Tengah Selatan Regency, Nusa Tenggara Timur Province
Authors: Ischak Wenny Ino
Published: November 2019

The introduction of feasible complementary foods at 6 months together with continued breastfeeding up to two years of age or beyond. is very important to infant. This study aimed to assess factors associated with the accuracy of the age of supplementary feeding to infant. This study used a cross-sectional design of community-based and carried out in nine districts in the Timur Tengah Selatan Regency,Nusa Tenggara Timur province. It was conducted of the month, October to December 2013 in 9 sub-districts selected. The research subjects were children aged 6-23 months (n = 3578). Data were collected by trained local personnel using a standardized questionnaire. This study showed that there is 77.4% of the respondents have given complementary feeding at suggested time (6 mounths). Type supplementary food given was 56.5% in the form of instant porridge. Giving of complementary foods at 6 months as recommended midwife was 34.6% whereas the reason that it was time to give complementary food before the age of 6 months was only 7.9%. it was found statistically significant where the correlation between giving complementary foods and regularly bring the child to the IHC was 93.7% (P = 0:02), while its relationship with the child's diet counseling ever got was 78.5% (P = 0.00).

Keywords: complementary foods; integrated health care; children 6-24 mounths of age
Exploiting Curcumin Synergy With Natural Products Using Quantitative Analysis of Dose–Effect Relationships in an Experimental In Vitro Model of Osteoarthritis
Authors: D’Ascola Angela , Irrera Natasha , Ettari Roberta , Bitto Alessandra , Pallio Giovanni , Mannino Federica , Atteritano Marco , Campo Giuseppe M. , Minutoli Letteria , Arcoraci Vincenzo , Squadrito Violetta , Picciolo Giacomo , Squadrito Francesco , Altavilla Domenica
Published: November 2019

Introduction: Drug combination is widely used to treat chronic inflammatory diseases. A similar strategy might be worth of interest to design plant-derived natural products to treat inflammatory conditions. Curcumin is a natural phenolic compound which shares anti-inflammatory activity with both flavocoxid, a flavonoid mixture of baicalin and catechin, and β-caryophyllene, a bicyclic sesquiterpene. The aim of this study was to investigate the synergy potential of curcumin with both flavocoxid and β-caryophyllene in human articular chondrocytes triggered with lipopolysaccharide (LPS), in an experimental in vitro model of osteoarthritis.

Materials and Methods: Human articular chondrocytes were stimulated with LPS alone or in combination with different treatments. Total RNA was extracted 4 h after treatment to study interleukin 1β (IL-1β), NF-κB, and STAT3 mRNA expression. A drug combination study was designed choosing 5 doses to demonstrate a synergistic effect of compounds, according to Chou and Talalay method. A median-effect equation was applied and finally, the combination index (CI) was used to clarify the nature of the compounds interaction (synergistic versus additive versus antagonistic inhibitory effects); CI < 1, CI = 1, and CI > 1 indicated synergistic, additive, and antagonistic effects, respectively.

Results: LPS prompted IL-1β expression. Curcumin, flavocoxid and β-caryophyllene suppressed IL-1β expression with different IC50. A synergistic action for the reduction of the inflammatory phenotype in human chondrocytes was observed for the combination curcumin-flavocoxid with a percentage from 10% to 90%, and for the combination curcumin-β-caryophyllene from 50% to 90%. IC50 doses of either flavocoxid, β-caryophyllene and curcumin alone or in combination were safe and did not affect cell vitality. Moreover, the same IC50 doses reduced the transcription factors NF-κB and STAT3 mRNA expression and interestingly the effects of the combinations were greater than the natural products alone, thus suggesting that the site where the synergy takes place could be at the signal transduction level.

Discussion: The results suggest that curcumin synergizes with either flavocoxid or β-caryophyllene, exerting an anti-inflammatory activity and thus strongly suggesting the potential of a dual combination of these compounds for the management of osteoarthritis and unmasking a new feature of these natural products.
An Improved Genetic Algorithm with Adaptive Variable Neighborhood Search for FJSP
Authors: Gu Xiaolin , Huang Ming , Liang Xu
Published: November 2019

For solving the complex flexible job-shop scheduling problem, an improved genetic algorithm with adaptive variable neighborhood search (IGA-AVNS) is proposed. The improved genetic algorithm first uses a hybrid method combining operation sequence (OS) random selection with machine assignment (MA) hybrid method selection to generate the initial population, and it then groups the population. Each group uses an improved genetic operation for global search, then the better solutions from each group are stored in the elite library, and finally, the adaptive local neighborhood search is used in the elite library for detailed local searches. The simulation experiments are carried out by three sets of international standard examples. The experimental results show that the IGA-AVNS algorithm is an effective algorithm for solving flexible job-shop scheduling problems.
Lysimeter-Based Water Use and Crop Coefficient of Drip-Irrigated Potato in an Arid Environment
Authors: Alataway Abed , Al-Ghobari Hussein , Mohammad Fawzi , Dewidar Ahmed
Published: November 2019

The determination of the water requirements and crop coefficient (Kc) of agricultural crops helps to create an appropriate irrigation schedule, and with the effective management of irrigation water. The aim of this research was to estimate the water requirement, Kc, and water-use efficiency (WUE) of potato using non-weighing-type lysimeters in four regions of the Kingdom of Saudi Arabia (Qassiem, Riyadh, Al-Jouf, and Eastern). Our results clearly show that the accumulated values of the measured crop evapotranspiration of potato derived from the lysimeters were 573, 554, 592, and 570 mm, while the accumulated values of the predicted crop evapotranspiration from Penman-Monteith equation based on FAO (Food and Agriculture Organization) were 651, 632, 672, and 647 mm for the Qassiem, Riyadh, Al-Jouf, and Eastern regions, respectively. The Kc values of potato obtained from the lysimeters were Kc initial (0.58, 0.54, 0.50, and 0.52), Kc middle (1.02, 1.05, 1.13, and 1.10), and Kc end (0.73, 0.74, 0.74, and 0.75) for the Qassiem, Riyadh, Al-Jouf, and Eastern regions, respectively. Based on the amount of water used and the yield achieved, the highest WUE (3.6 kg m−3) was observed in the Riyadh region, while the lowest WUE (1.5 kg m−3) was observed in the Al-Jouf region.
3Rs-Related and Objective Indicators to Help Assess the Culture of Care
Authors: Hawkins Penny , Bertelsen Thomas
Published: November 2019

Within animal research and testing, the need for an effective Culture of Care is widely recognized and described in terms of an establishment-wide commitment to improving the implementation of the 3Rs, animal welfare, scientific quality, care of the staff, and transparency for all stakeholders, including the public. Ideally, each establishment would determine what the Culture of Care means for them, and be able to assess and potentially benchmark their own culture. Some establishments already do this, using various indicators and formal or informal assessments. This paper provides examples of these approaches to assessing the Culture of Care, including surveys and surrogate measures. Many currently-used criteria and indicators tend to be human-centric and subjective, and we suggest using further objective indicators and animal-centric, 3Rs-based criteria. It is preferable to consider each of the 3Rs separately when assessing culture, and some indicators are suggested to facilitate this. Several documents produced by regulators in the UK and European Union are good sources of objective indicators of a good Culture of Care. This concept paper aims to complement the literature on assessing the Culture of Care, providing ideas and sources of information to help identify relevant and measurable criteria.
Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature
Authors: Moysa Cozette , Murtagh Ross , Lambert John S.
Published: November 2019

This report describes the case of an individual who was clinically diagnosed with Lyme borreliosis and initially responded to standard antibiotic therapy. Subsequent to treatment cessation, the patient experienced symptomatic rebound and failed to respond to a second course of the same antibiotic. The patient was eventually diagnosed with both Borrelia and Anaplasma infections by serological testing performed in a private laboratory. Following a two-month course of combination antibiotic therapy, the patient responded clinically, with a return to almost normal functioning. We discuss this case in the context of recent pre-clinical research examining potential Borrelial persistence despite antibiotic therapy.
Cost Consensus Algorithm Applications for EV Charging Station Participating in AGC of Interconnected Power Grid
Authors: Tang Jun , Ma Xiang , Gu Ren , Yang Zhichao , Li Shi , Yang Chen , Yang Bo
Published: November 2019

In order to more effectively reduce the regulation costs of power grids and to improve the automatic generation control (AGC) performance, an optimization mathematical model of generation command dispatch for AGC with an electric vehicle (EV) charging station is proposed in this paper, in which a cost consensus algorithm for AGC is adopted. Particularly, virtual consensus variables are applied to exchange information among different AGC units. At the same time, the actual consensus variables are utilized to determine the generation command, upon which the flexibility of the proposed algorithm can be significantly enhanced. Furthermore, the implement feasibility of such an algorithm is verified through a series simulation experiments on the Hainan power grid in southern China, where the results demonstrate that the proposed algorithm can effectively realize an autonomous frequency regulation of EVs participating in AGC.
A Short Survey and Open Questions on Compact Q-Groups
Authors: Russo Francesco G.
Published: November 2019

Finite Q -groups have been recently studied and form a class of solvable groups, which satisfy interesting structural conditions. We survey some of their main properties and introduce the idea of Q -group for compact p-groups (p prime). A list of open questions is presented, along with several connections of arithmetic nature on a problem originally due to Frobenius.
Association of RS708272 (CETP Gene Variant) with Lipid Profile Parameters and the Risk of Myocardial Infarction in the White Population of Western Siberia
Authors: Semaev Sergey , Shakhtshneider Elena , Orlov Pavel , Ivanoshchuk Dinara , Malyutina Sophia , Gafarov Valery , Ragino Yuliya , Voevoda Mikhail
Published: November 2019

The TaqI B (rs708272) single-nucleotide variant, i.e., the +279 G/A substitution in intron 1 of the CETP gene, is actively investigated as a risk factor of lipid metabolism disorders. The aim of this study was to analyze the association of rs708272 with lipid parameters and the risk of myocardial infarction in the population of Western Siberia (Russia). The study population was selected from a sample surveyed within the framework of the Health, Alcohol and Psychosocial Factors In Eastern Europe (HAPIEE) study (9360 participants, >90% white, aged 45–69 years, males: 50%). In total, 3132 randomly selected patients were included. Plasma lipid levels were determined by standard enzymatic assays. Rs708272 was analyzed by RT-PCR via TaqMan single-nucleotide polymorphism (SNP) Genotyping Assays (Thermo Fisher Scientific, USA). The frequencies of rs708272 genotypes AA (homozygote), AG (heterozygote), and GG were 0.21, 0.49, and 0.30, respectively, in this population. Allele A frequency was 0.46. We found an association of allele G with low levels of high-density lipoprotein cholesterol and a high index of atherogenicity in this population (p < 0.001 and p < 0.001, respectively). Allele G was significantly associated with the risk of myocardial infarction among the male participants (odds ratio 1.96, 95% confidence interval 1.208–3.178, p = 0.008) and in the study population (odds ratio 1.465, 95% confidence interval 1.028–2.087, p = 0.036). Thus, rs708272 is associated with myocardial infarction in the white population of Western Siberia (Russia).