bluuebunny/crossref_metadata_2025 huggingface dataset:
INTERFACE ENTRE SAÚDE MENTAL E OBSESSÃO NO CONTEXTO DA DOUTRINA ESPÍRITA-CRISTÃ
Authors: Hott Márden Cardoso Miranda
Published: March 2021

Entrevista realizada com Eugênio Eustáquio dos Santos, curador da Casa Chico Xavier, presidente da Aliança Municipal Espírita de Pedro Leopoldo e Matozinhos, e dirigente do Centro Espírita Meimei, localizados em Minas Gerais. A abordagem é direcionada para uma das vertentes da Doutrina Espírita-Cristã, a obsessão, considerando a vasta experiência do entrevistado com a tônica. O problema possivelmente de origem espiritual pode afetar a condição pessoal, familiar e social do obsediado, sendo que, por vezes, é considerado, equivocadamente, como um distúrbio da saúde mental do portador. O inquérito tem por objetivo colaborar para o avanço no entendimento do tema que é notadamente recorrente e incidente na população brasileira, embora seja relegado e pouco explorado. As questões foram respondidas em setembro de 2020, via plataforma de pesquisa online.
Die Entwicklung von Forschungssoftware als praktische Interdisziplinarität
Authors: von Nordheim Gerret , Koppers Lars , Boczek Karin , Rieger Jonas , Jentsch Carsten , Müller Henrik , Rahnenführer Jörg
Published: March 2021

Wir stellen in diesem Aufsatz ein Modell interdisziplinärer Zusammenarbeit zwischen Kommunikationswissenschaft und Methodenwissenschaft (hier: Statistik) vor. Dabei steht die Frage im Mittelpunkt, wie sich die Kollaboration grundverschiedener Disziplinen über einen längeren Zeitraum verstetigen lässt. Der agilen Entwicklung von Forschungssoftware, die die fachübergreifende Zusammenarbeit strukturiert, kann hierbei eine zentrale Rolle zukommen. Sie ermöglicht zwei Ebenen der Zusammenarbeit mit verschiedenen Zeithorizonten: auf der einen werden zeitlich begrenzte Projekte umgesetzt, auf der anderen die längerfristige Zusammenarbeit organisiert. Wechselnde Team-Konstellationen und Hierarchien ermöglichen kontinuierlichen Wissensaustausch, die verwendete Programmiersprache ist Grundlage für die Entstehung einer fächerübergreifenden Kommunikation und die Orientierung auf ein gemeinsames Produkt schafft eine Kultur der gemeinsamen Verantwortlichkeit. Um die theoretischen Reflexionen an der Forschungspraxis zu spiegeln, greifen die Autor*innen auf ihre Erfahrungen im Kontext des Dortmund Center für datenbasierte Medien-Analyse (kurz: DoCMA) zurück. DoCMA ist deswegen als Fallbeispiel relevant, da Struktur und Organisation hier auf die Erfordernisse der agilen Entwicklung offener Forschungssoftware ausgerichtet wurden.
Co-Creation als Entwicklungsmethode. Zu Möglichkeiten und Grenzen partizipativer Forschungssoftwareentwicklung am Beispiel der Sortiersoftware MeSort und Tagebuchsoftware MeTag
Authors: Hohmann Florian
Published: March 2021

Die Verwendung von Forschungssoftware zur Unterstützung methodischer Vorgehensweisen insbesondere bei Untersuchungen zu Mediennutzung oder -aneignung innerhalb digitaler Medienumgebungen bietet Vorteile etwa bei der Datensammlung, -auswertung oder -darstellung. Forschungssoftware ist jedoch häufig sehr spezialisiert und an eher kleine Zielgruppen gerichtet. Diese haben einerseits sehr spezielle Ansprüche an die Funktionen einer solchen Software und sind andererseits, indem sie sie aktiv nutzen, wichtig für die Nachhaltigkeit und damit Langlebigkeit der Forschungssoftware. Eine Möglichkeit, Zielgruppenansprüche und Softwarenachhaltigkeit gewinnbringend miteinander zu vereinen und den Nutzerkreis der Forschenden schon bei der Softwareentwicklung zu involvieren, bietet der Co-Creation-Ansatz. Im Artikel wird gezeigt, wie der Einsatz von Co-Creation bei der Entwicklung von Forschungssoftware angewendet werden kann. Illustriert wird dies am Beispiel der beiden Programme MeTag und MeSort, die derzeit am ZeMKI in Bremen im Rahmen eines DFG-Projektes entstehen. Zunächst wird demonstriert, welche Vorteile der Einsatz von Forschungssoftware insbesondere zur Unterstützung cross-medialer Methoden in der Mediatisierungsforschung gegenüber herkömmlichen Vorgehensweisen bietet, und dann mit der Beschreibung zweier Workshops gezeigt, wie der Co-Creation-Ansatz bei der Entwicklung dieser Software im Projekt umgesetzt wurde.
Rechtliche Rahmenbedingungen für die Suche nach einem Endlager für hochradioaktiven Abfall (HAW)
Authors: Emanuel Florian
Published: March 2021

Producing nuclear energy inherently produces high active nuclear waste (HAW), which has to be disposed of properly and safely. Disposal of HAW represents an eternal burden of nuclear power – even after the German nuclear phase-out in 2022. This intergenerational challenge is a challenge for many more countries than just Germany. Up to date, in the whole world, there is not one operational disposal facility for HAW.

The author deals with the constitutional requirements for the German Site Selection Process and the evaluation criteria derived from the constitution. Based on an international legal comparison, he finally develops recommendations concerning a further legal development of this process. The legal comparison particularly emphasizes Canada, Switzerland and Finland.
Regulatory T Cells in the Mosaic of Liver Transplantation Tolerance
Authors: Terzieva Velislava , Uzunova Yordanka , Gornev Radosvet , Spassov Lubomir
Published: March 2021

The success of transplantation depends on multiple factors, but the establishment of immune tolerant milieu is of critical importance. Hepatic environment consists of different cellular populations with prominent capacity to tolerate a huge range of antigens. Among them, regulatory T cells (Tregs) play an important role. They control the strength of immune reactions against non-self antigens and were shown to have an impact on the establishment of immune tolerance in the post-transplantation period. Furthermore, they impact a particular state after transplantation – operational tolerance. The abundant data show that Tregs might be manipulated, which suggests their further implementation as a treatment strategy. Tregs are also a very attractive target as a biomarker in the monitoring of post-transplantation period. Here, we review the particular role of Tregs among the broad spectrum of immune tolerance mechanisms of the liver in the light of the current directions of medical research.
A Survey on Weapon Target Allocation Models and Applications
Authors: Asadi Ghanbari Abdolreza , Mohammadnia Mousa , Abbas Sadatinejad S. , Alaei Hossein
Published: March 2021

In Command and Control (C2), Threat Evaluation (TE) and Weapon Target Allocation (WTA) are two key components. To build an automated system in this area after modeling Threat Evaluation and Weapon Target Allocation processes, solving these models and finding the optimal solution are further important issues. This setting demands instantaneous operational planning and decision making under inherent severe stress conditions. The associated responsibilities are usually divided among a number of operators and also computerized decision support systems that aid these operators during the decision making process. In this Chapter, the literature in the area of WTA system with the emphasis on the modeling and solving methods are surveyed.
Continuous Curvilinear Capsulorhexis
Authors: Qian Liu
Published: March 2021

Continuous curvilinear capsulorhexis (CCC) is an important step in of modern phacoemulsification, which has crucial influence on the surgical process and prognosis. In this chapter, we mainly discuss following aspects: Preoperative preparation, Effects of incision on capsulorhexis, Capsulorhexis, Special cases of capsulorhexis and Capsulorhexis assisted by femtosecond laser. The problem need to pay attention and the solution way in above aspects will be elaborated.
Internet of Things Security and Privacy
Authors: J. Showail Ahmad
Published: March 2021

The Internet of Things is becoming more and more popular with time. The extremely low cost of sensors is putting the growth of the Internet of Things on steroids. Many industries such as healthcare, construction, agriculture, and transportation are increasingly leveraging this technology. However, security and privacy are two big concerns when it comes to the future of the Internet of Things. Since most of these “things” that are connected to the Internet are simple devices with limited hardware capabilities, it is nearly impossible to harden them via traditional resource-heavy defenses. In this chapter, we discuss the importance of securing the Internet of Things networks, layout the challenges of the Internet of Things security, and briefly discuss potential solutions in the literature.
COVID-19 or Influenza, or Both? A Comparison and Algorithmic Approach to Management
Authors: Karimi Abdollah , Rafiei Tabatabaei Sedigheh , Shiva Farideh , Hoseinialfatemi Seyedeh Mahsan
Published: March 2021

Context: First cases of Coronavirus disease 2019 (COVID-19) were reported in December 2019. With more than 100 million confirmed cases 14 months later, the disease has become the worst public-health dilemma of the century. The rapid global spread of COVID-19 has resulted in an international health emergency, threatening to overwhelm health care systems in many parts of the world, especially poor resource countries. Evidence Acquisition: Influenza and COVID-19 have similar clinical symptoms, and both cause a respiratory illness that may vary from mild to severe. Both diseases have the same mode of transmission and require similar public health guidelines to prevent their spread, but their treatment strategies are different. In this study, an algorithmic method is proposed for managing patients according to their symptoms for each of these infections. Results: In fall and winter, infections with seasonal influenza and other respiratory viruses become common. As influenza also causes significant morbidity and mortality, especially at the two extremes of age and in those with compromised immunity, it is of major importance to know the similarities and dissimilarities between COVID-19 and seasonal influenza and plan appropriate public health measures to deal with each of these illnesses. Conclusions: Will there be a devastating combined epidemic of COVID-19 and influenza (COV-Flu) during the 2020 - 2021 season? Does co-infection increase the risk of severe illness or amplify virus shedding? Actually, we do not yet know the answers to these questions; so, in this article, first, we attempt to define the similarities and differences between COV-Flu. Then, we will have a brief discussion on how to manage patients presenting with symptoms suggestive of both diseases. However, as COVID-19 has been recognized as a pandemic since December 2019, the management of this emerging disease is rapidly evolving as new information is collected from different parts of the world.
The Effect of Pilates Training on Body Composition, Lipid Profile, and Serum 25-Hydroxy Vitamin D Levels in Inactive Overweight Women
Authors: Khajehlandi Mojdeh , Mohammadi Robabeh
Published: March 2021

Background: The increasing prevalence of overweight and related diseases has gained more scientific attention. Overweight and obesity are known as a threat to health, and low serum 25-hydroxy vitamin D levels is associated with obesity. Objectives: Therefore, we examined the effect of Pilates training on body composition, lipid profile, and serum 25-hydroxy vitamin D levels in inactive overweight women. Methods: In this clinical study, 28 overweight women were randomly divided into a training group (n = 14) and a control group (n = 14). Pilates training was performed three 60-min sessions during 12 weeks. In two stages, blood samples were collected 48 hours before and after the last protocol exercise training session. During the 12 weeks, the control group had no exercise training. For analyzing within- and between-group changes, paired t-test and ANCOVA with the significant level of P < 0.05 were used, respectively. Results: After 12 weeks of Pilates training in the training group compared to the control group, there was a significant decrease in the body mass index (P = 0.005), cholesterol (P = 0.001) and triglyceride (P = 0.001) values, and serum 25-hydroxy vitamin D levels (P = 0.005), while high-density lipoprotein (P = 0.028) increased significantly. However, no significant change was observed in low-density lipoprotein levels (P = 0.435). Conclusions: According to the results, it can be indicated that 12 weeks of Pilates training have improved serum 25-hydroxy vitamin D levels, changed anthropometry, and lipid profile in inactive overweight women.
Delayed Replantation of Avulsed Teeth: A Case Report
Authors: Ameli Sahar , Jafari Karim , Zadfatah Firouz , Blurian Mehrdad , Hekmatfar Somayeh
Published: March 2021

Introduction: Dental avulsion is a severe injury in which the tooth is totally displaced out of its alveolar socket. Replantation of avulsed teeth is a standard procedure. The success of the treatment of traumatized teeth revolves around the status of periodontium since it is a vital structure. Furthermore, other factors, including extra-alveolar time period, choice of storage media, and contamination of the avulsed tooth, can determine the success of replantation. Delay in the replantation of avulsed incisors increases the risk of dentoalveolar ankylosis and replacement root resorption. Case Presentation: This case report presented a 9-year-old girl with tooth avulsion subjected to a 3-year follow-up after the replantation of avulsed maxillary central incisors kept in dry conditions for seven days. The avulsed mature permanent teeth were managed through the application of treatment guidelines with prolonged extra-oral time. The avulsed teeth were replanted and splinted for four weeks. The canals of both teeth were filled with calcium hydroxide and replaced by mineral trioxide aggregate after six months. Two months after replantation, there were signs of external root resorption in tooth 21. Conclusions: In the third year of follow-up, both teeth were infraoccluded, although they had an acceptable level of functionality and appearance. These ankylosed incisors can be managed successfully with the decoronation technique in the future.
The Prevalence of Hepatitis B and C Virus Infections in the Couples Attending a Premarital Screening Program in Zakho City, Kurdistan Region of Iraq
Authors: Jamal Shakir Abdulrahman , Naqid Ibrahim Abdulqader , Hussein Nawfal Rasheed , Abdulqader Solav Rashed , Nimet Avan Ali , Abdulkhdair Haider Adil , Qader Ramyar Abubakr
Published: March 2021

Background: Hepatitis B and C virus (HBV and HCV) infections are major global health issues and the leading causes of liver cirrhosis and hepatocellular carcinoma. Objectives: The aim of this study was to investigate the prevalence of HBV and HCV infections in couples attending a premarital screening program in Zakho city, Kurdistan region, Iraq. Methods: This cross-sectional study was carried out in Zakho city, Kurdistan Region of Iraq, between January and October 2019. During this period, 2123 couples were screened for HBV and HCV as a part of premarital screening. The age of couples ranged from 18 to 63 years old. ELISA test was used to detect HBsAg, HBc IgG, and HCV Ab. Hepatitis C virus Ab positivity was then confirmed by HCV RT-PCR, and all HCV positive patients were then tested for genotyping. Results: Among the recruited subjects, 38/4246 (0.89%) patients were positive for HBsAg. Of these, 12/2123 (0.57%) were females, and 26/2123 (1.22%) were males. Hepatitis C virus RT-PCR confirmed HCV positivity for one female patient who was further confirmed to be infected with HCV genotype 4. Conclusions: To conclude, the present study showed a relatively low prevalence of HBV and HCV infections in the couples tested through the premarital screening program in Zakho city. The prevalence of HBV seropositivity was higher in males than females. Therefore special attention should be paid to males during prevention strategies.
Association of Medication Regimen Complexity With Clinical Endpoints in Pediatric Patients With Cystic Fibrosis
Authors: Tjugum Shelby L. , Hansen B. Kyle , McKinzie Cameron J.
Published: March 2021

OBJECTIVE

Cystic fibrosis (CF) patients and caregivers are impacted by the number of pharmacological agents and unique administration needs; however, no data currently assesses how medication regimen complexity impacts clinical outcomes in this population. The objective of this study is to evaluate if an association exists between increased medication regimen complexity and clinical endpoints in pediatric patients with CF.

METHODS

This retrospective analysis included all pediatric patients with CF (ages 5–20 years) with at least 2 pharmacist encounters and acceptable pulmonary function tests at our pediatric pulmonary clinic during 2017. Each patient's medication regimen was scored using the validated Medication Regimen Complexity Index (MRCI) tool. The primary outcome was the correlation between MRCI score and lung function. Secondary endpoints included growth, number of infections requiring antibiotics, and hospitalizations.

RESULTS

MRCI scores of the 113 included patients ranged from 2 to 101 points. A negative correlation was found between initial and final MRCI score and initial and final forced expiratory volume in 1 second (FEV1; r = −0.323, p = 0.0005 and r = −0.287, p = 0.0021, respectively). MRCI scores were negatively correlated with BMI percentile for both encounters (r = −0.162 and r = −0.125) but were not significant. Higher MRCI scores were associated with increased use of oral and intravenous antibiotics and hospital admissions.

CONCLUSIONS

Higher MRCI scores are correlated with a significant decrease in FEV1, increased need for antibiotic therapy, and more hospital admissions in pediatric patients with CF. Larger studies are needed to determine if a correlation exists between MRCI score and growth.
An Evaluation of Twice-Daily Dosing of Caffeine for Apnea of Prematurity
Authors: Rebentisch Aubrey , Kovey Karen , Denslow Sheri
Published: March 2021

OBJECTIVE

Preterm infants often require caffeine for the treatment of apnea. While the maintenance dose of caffeine citrate is usually administered once daily per FDA labeling, many providers administer the maintenance dose in two divided doses. This study evaluated the effectiveness of a twice daily dosing regimen of caffeine for apnea of prematurity.

METHODS

This was a retrospective analysis conducted from 2013–2018 that included preterm infants who received caffeine that was dosed both once and twice daily respectively. The primary outcome of our study was a composite of the number of apneic and bradycardic events for five 24-hour periods prior to switching to twice daily dosing of caffeine and five 24-hour periods after switching to twice daily dosing of caffeine.

RESULTS

The median five-day average incidence of apnea and bradycardia during the once and twice daily dosing periods was 6.2 events and 6.4 events respectively (p=0.09).

CONCLUSIONS

There is little benefit of twice daily dosing of caffeine for apnea of prematurity.
Evaluation of the Development of Tolerance Following Frequent Administration of Propofol in Children Requiring Successive Sedation for Separate Procedures
Authors: Shaikh Nadia , Tallman Brandon , Wang Yanzhi , Deshpande Girish , Tripathi Sandeep
Published: March 2021

OBJECTIVE

Propofol is frequently used for outpatient sedation for pediatric patients, some of whom require multiple rounds of sedation for separate procedures within a short period. Anecdotal experience suggests that frequent use of propofol results in escalating doses; however, clinical evidence is unconvincing. This study was designed to evaluate if tolerance develops with frequent administration of propofol for children requiring multiple successive sedations.

METHODS

A retrospective chart review of patients requiring multiple doses of propofol for separate procedures from 2011 through 2019 was conducted. Cumulative propofol dose and induction dose were analyzed using a mixed model for patients requiring sedation for serial procedures.

RESULTS

Data from 24 different patients who required 3 or more sedations during the study period were analyzed. The number of sedations ranged from 3 to 28. The mean total propofol dose rate was 0.19 ± 0.14 mg/kg/min, and the mean induction dose was 3.2 ± 0.97 mg/kg. The total doses and induction doses were not statistically significantly different at different sedations (p = 0.089 and 0.180, respectively). There was a statistically significant decrease in the total dose as the time interval between 2 sedations increased (p < 0.001).

CONCLUSIONS

Repeated administrations of propofol at time intervals used in outpatient sedation do not lead to the development of tolerance. A small decrease per day interval may be significant when propofol is used more frequently (multiple times per day or as a continuous drip) in an ICU setting.
Cardiac Arrest Following the Administration of Intravenous Diphenhydramine for Sedation to an Infant With Congenital Heart Disease
Authors: Andersen Courtney L. , Tobias Joseph D.
Published: March 2021

Diphenhydramine (Benadryl) is a first-generation antihistamine that is used primarily to treat allergic reactions including anaphylaxis, urticaria, and allergic rhinitis. Despite its availability as an over-the-counter medication, toxicity may occur with its use especially when administered in large doses or via the intravenous route. We present a 3-month-old infant with Trisomy 21 who suffered a cardiac arrest immediately following administration of a single 1.25 mg/kg dose of intravenous diphenhydramine, prescribed for sedation in the Pediatric ICU setting. The potential cardiovascular and respiratory effects of diphenhydramine are presented, previous reports of life-threatening adverse effects reviewed, and options to limit these effects discussed.
The company size as a determinant of financial result
Authors: Ševkušić Ljubiša
Published: March 2021

In different studies examined the determinants that significantly determine a company's financial performance. The size of the company is often mentioned as a determinant of the financial result. However, the results of researchs by authors around the world are not uniform, so we have claims that the size of the company positively affects the financial result, the size of the company negatively affects the financial result and researchs that emphasizes the lack of influence of company size on the financial result. In accordance with that, the main goal of the article is to use scientific methods to examine through empirical research whether the size of a company is a determinant of the financial result of a company in Serbia. The results of the research show that there is a statistically significant correlation between the size of the company and the financial result, ie that large companies in the real sector are more profitable compared to smaller companies.
Ergonomic risk assessment of the press machine for casava chips in SMEs-Karya Lestari Jaya: A case study
Authors: Hakim Silviana , Hardianto Andy , Fuhaid F , Hermawan Dadang
Published: March 2021

This article discusses about the press machine posture movement effectiveness for cassava chips mold. This research was conducted at Karya Lestari Jaya which is one of the SMES in Tulungagung, East Java, Indonesia. The industry is in trouble with new manual press machine that is too rigid and heavy to handle. The operator complain of pain the arm and forearm. this means the activity has deficient posture when the operator works. This study aims to know the ergonomics risk factors for press machine and determine the best recommendation by the operator and owner SMEs Karya Lestari Jaya suggestion. We conduct a case study by collect the data from observation. We analyze the observation data by RULA (Rapid Upper Limb Assessment). Then, we do interview of eight resource person to get the attribute that required to upgrade the machine. Besides that, we analyze the best recommendation by AHP (Analytic Hierarchy Process). This research result a value of RULA 6 which means the attitude in pressing the dough or working facilities need to repair immediately. There are five phases to determine design there are information phase, creative phase, analyze phase, development phase and recommendation phase and the result of AHP show that the best recommendation is the addition of a pneumatic system in machine press to lighten the lever. In the end, this research can be useful to the company by knowing body posture and evaluating the upgrade machine.
Design development and technical analysis of an auto checking hardness machine: A study case of the hardness tester HR-522 series
Authors: Caesar Bernardus , Dzulfikar Muhammad , Prabowo Aditya , Pratama Pandu , Cho Joung
Published: March 2021

A hardness-checking machine is a crucial tool in engineering studies, especially in mechanical and manufacturing processes. It is usually used to measure, calibrate, and standardize the quality of products. This study is based on the field problem in Akebono Brake Astra, Indonesia, where more manual tools are used to meet product demands. In consideration of this issue, a modified hardness checking tool with automatic operation has been developed. Using automatic operation is beneficial in terms of time and cost efficiency in comparison with other manual tools. Automatic tools apply the 3-axis system mechanism, using a Festo linear actuator with a servo motor. The testing capacity of automatic devices is equal to more manual devices. The frame of the auto checking hardness machine is assessed in this study by applying load variations. Drawing on other similar work on auto checking hardness machines, this paper provides a comparison of various aluminum frame types based on different tensile strengths and cross-sectional area values. The baseplate for hardness testing is also calculated. There are 9 testing points for calculating the use of linear guides for the baseplate. The results show excellent tensile strength values, as well as a good displacement and maximum stress.
Connection between the disorder of the function of the thyroid gland and the appearance of the somatic symptoms with the patients
Authors: Stanić Gordana , Marinković Snežana
Published: March 2021

Introduction: The thyroid gland is one of the most important endocrine glands that has the function of releasing hormones that regulate metabolism in adults. Thyroid hormones act directly or indirectly on almost all systems in the body, so they can negatively affect the health of an individual, who have a high risk of developing disorders in psychosomatic symptoms. The occurrence of somatization in patients can be accompanied by a direct impact of thyroid disorders on certain organs and systems, but it can also be non-specific in relation to the disease itself. Objective: To examine the relationship between different disorders of the thyroid gland and the occurrence of somatic symptoms in patients, according to age, body mass index and length of treatment. Material and methods: The study was conducted as a cross-sectional study in 221 outpatients with thyroid disease at the Special Hospital for Thyroid Diseases and Metabolic Diseases "Zlatibor", from February to July 2018. In addition to the sociodemographic questionnaire, a four-dimensional symptom questionnaire subscale (4DSQ) was used in the study to assess the occurrence and level of somatization in subjects. Results: There is an association between different thyroid disorders and a high score on the somatization scale (16.05 ± 8.34), in 69.7% of subjects. In our subjects, the most pronounced somatic symptoms have subjects with hypothyroidism (M = 17.5; as = 16.44 ± 8.26), subjects over 61 years (19.29 ± 8.29). Musculoskeletal somatic symptoms were expressed in 72.4% of subjects. Pronounced somatization (19.40 ± 8.32) have subjects who have elevated body mass index values (35-39.9), as well as subjects who have been treated for thyroid disease for more than ten years (19.7 ± 8.7). Conclusion: This study showed that there is an association between thyroid disorders and the appearance of somatic symptoms in patients. In patients, there are moderate somatic symptoms that are associated with age, body mass index and length of treatment.
Produtos midiáticos
Authors: Silva Lara Lodi da , Sousa Richard Perassi Luiz de
Published: March 2021

Atualmente na cultura de mercado, é possível ver marcas gráficas de grifes de moda estampando produtos, sendo também publicamente expostas como símbolos que identificam, distinguem e representam os seus usuários. Esse movimento, demonstra uma identificação e um acordo tácito de correlação entre a exposição pública do indivíduo com a marca, devido à esta forma de expressão identitária que, ao mesmo tempo, difere e representa o produto e o usuário. Este artigo desenvolve, um estudo exploratório descritivo-qualitativo do fenômeno chamado "Logomania", assim, como referência especial para os fashionistas, as marcas gráficas de grifes são publicamente expostas como entidades de culto e devoção, o que caracteriza este movimento "logomaníaco" como um meio de identificação dos usuários, sendo comumente observado na mídia de moda e consequentemente na cena urbana. A partir desse argumento através da fundamentação teórico-mercadológica a conceito de métodos de pesquisa ao estudo, propõe-se apresentar o fenômeno indicado, com a revisão e a aplicação sistemática de conceitos e contribuições teóricas sociais ligados a ele a cerca de considerações envolvendo Mídia, Moda, Marca e Cultura de Mercado
The transcendentalist turn of the new post-postmodern American literature
Authors: Bolaño Quintero Jesús
Published: March 2021

Este artículo responde al debate que se produce en el campo de la teoría literaria en torno a la naturaleza de la novela estadounidense postmoderna. Mientras que algunos autores afirmaron a principios del milenio que la novela estaba muerta, una nueva generación de jóvenes escritores estadounidenses fueron responsables de un nuevo compromiso con el género por parte del público. Con esto en mente, este estudio busca arrojar luz sobre la naturaleza de la literatura escrita por estos novelistas que buscan distanciarse del callejón sin salida del posmodernismo. Nuestra premisa es que durante la crisis de principios del siglo veinte, que provoca un replanteamiento del concepto de posmodernidad, los jóvenes autores estadounidenses volvieron su mirada hacia las ideas del trascendentalismo estadounidense como una herramienta para recuperar el proyecto inacabado de la modernidad interrumpido por el postmodernismo.

This article responds to the debate in the field of literary theory around the nature of post-postmodern American novels. While some authors claimed at the turn of the millennium that the novel was dead, a new generation of American writers were responsible for a new engagement with the genre on the part of the public. With this in mind, this study seeks to shed light on the nature of the literature written by young novelists seeking to distance themselves from the dead end of postmodernism. Our premise is that during the crisis that brings about a rethinking of the concept of postmodernity, the young American authors turned their gaze towards ideas from American transcendentalism as a tool to recover the unfinished Project of modernity.
La posibilidad cómica en las estéticas de la negatividad
Authors: Ortiz de Urbina Arandigoien Xabier
Published: March 2021

El presente artículo pretende ofrecer una actualización acerca de la relación entre la experiencia humorística y las llamadas estéticas negativas. Desde que Aristóteles definiera la comedia como la imitación de los rasgos ridículos del ser humano, los cuales pertenecen a la categoría de lo feo, lo cómico y lo humorístico han sido muchas veces enumerados dentro de las categorías estéticas de la negatividad frente a las estéticas relacionadas con la belleza. En contraposición, se encuentran teorías como las de Theodor Lipps, quien asegura que el valor de la comicidad no es un valor estético, sino que responde a una forma de juicio distinta, como también adelantó el propio Kant. Se pretende así plantear una discusión a partir de estos dos postulados y ofrecer una posible salida.

This article aims to offer an update on the relationship between the humorous experience and negative aesthetics. Since Aristotle defined comedy as the imitation of the ridiculous traits of the human being, as a part of the ugly aesthetics, the comic and the humorous have often been listed within the aesthetic categories of negativity in front of the aesthetics related to beauty. In contrast, there are theories like those of Theodor Lipps, who assures that the value of humor is not an aesthetic value, but responds to a different form of judgment, as Kant also advanced. The aim is to propose a discussion based on these two postulates and offer a possible solution.
Una introducción al pensamiento de Marina Garcés
Authors: Castany Prado Bernat
Published: March 2021

Este artículo presenta de forma divulgativa y ordenada el pensamiento de la filósofa Marina Garcés. Siguiendo los cuatro momentos básicos en los que la filosofía clásica suele estructurarse, exponemos su epistemología, su ontología, su ética y su política, insistiendo siempre en el carácter práctico de su pensamiento.

This article presents in an informative and orderly way the thought of the philosopher Marina Garcés. Following the four basic moments in which classical philosophy is usually structured, we expose its epistemology, its ontology, its ethics and its politics, insisting on te practical nature of its thought.
Presentación
Authors: Hernández González María Belén , Pujante Segura Carmen María
Published: March 2021

Presentación de las coordinadoras y breve antología de Gaya.
La détermination des unités de négociation dans le secteur public fédéral : la langue et la culture entre approches fonctionnelle et volontaire
Authors: Coutu Michel
Published: March 2021

La détermination des unités de négociation, élément crucial de cristallisation de la liberté d’association depuis l’adoption au Canada du modèle Wagner (1944), obéit à des règles différentes du régime général dans le secteur public. En règle générale, la détermination de l’unité d’accréditation y repose avant tout sur des critères fonctionnels, telles la structure organisationnelle de l’entreprise ou la similarité des fonctions et des conditions de travail, par opposition à des critères volontaires qui feraient entrer en jeu, en toute priorité, les choix associatifs des employés. Dans le présent texte, l’auteur retrace l’historique de la détermination des unités de négociation dans le secteur public fédéral et examine les composantes respectives des approches fonctionnelle et volontaire, en comparant deux situations types, soit celles qui sous-tendaient les demandes de fragmentation des unités de négociation à la Société Radio-Canada en 1978 et chez les contrôleurs aériens au Québec en 1979. Les types idéaux du fonctionnalisme et du volontarisme sont ensuite mobilisés pour l’analyse de la situation contemporaine à la Gendarmerie royale du Canada, laquelle a fait l’objet, au regard de la liberté constitutionnelle d’association, d’une décision récente (juillet 2019) de la Commission des relations de travail et de l’emploi dans le secteur public fédéral.
Ameliorative effect of apelin-13 against renal complications in L-NAME-induced preeclampsia in rats
Authors: Hamza Reham Z. , Diab Abdel Aziz A. , Zahra Mansour H. , Asalah Ali K. , Attia Mai S. , Moursi Suzan MM
Published: March 2021

Pre-eclampsia (PE) accompanying acute liver and kidney injury has remained a master cause of both fetal and maternal mortality and morbidity. Vasoactive mediators, oxidative stress and inflammatory imbalanceshave an important role in PE pathogenesis. Apelin is an adipokine that improves endothelial dysfunction; has anti-inflammatory and antioxidant effects; moreover, its level reduced during PE. This study aimed to explore the effects of apelin-13 administration on preeclampsia-associated renal dysfunction and proteinuria. Thirty-three pregnant female rats were divided into three groups; group: 1 (normal pregnant rats), group: 2 (preeclamptic rats); where rats were injected subcutaneously with 75 mg L-NAME/ kg body weight/day beginning from 9th to 20th day of pregnancy andgroup 3 (apelin-13 treated preeclamptic rats); In which L-NAME-induced preeclamptic rats were subcutaneously injected with 6 × 10−8 mol apelin-13/kg body weight/twice daily starting from 6th to 20th day of pregnancy. In all groups, mean arterial blood pressure, total urine protein, serum urea, creatinine, nitric oxide (NO), endothelin-1 (ET-1), interleukin–6 (IL-6) and malondialdhyde (MDA) were measured. Histopathological examination of kidney tissues was also done. preeclamptic rats showed significantly increased mean arterial blood pressure, total urine proteins, serum urea, creatinine, ET-1, IL-6, and MDA, but revealed a significantly decreased serum NO level. On the other hand, apelin treatment significantly improved these parameters together with amelioration of kidney histoarchitecture in the treated group. In conclusion, apelin may be a potentially curative candidate for prohibiting kidney damage and have a therapeutic benefit in PE rat models.
Transcriptome analysis revealed gene regulatory network involved in PEG-induced drought stress in Tartary buckwheat (Fagopyrum Tararicum)
Authors: Huang Juan , Chen Qijiao , Rong Yuping , Tang Bin , Zhu Liwei , Ren Rongrong , Shi Taoxiong , Chen Qingfu
Published: March 2021

Tartary buckwheat is a nutritious pseudo-cereal crop that is resistant to abiotic stresses, such as drought. However, the buckwheat’s mechanisms for responding to drought stress remains unknown. We investigated the changes in physiology and gene expression under drought stress, which was simulated by treatment with polyethylene glycol (PEG). Five physiological indexes, namely MDA content, H2O2 content, CAT activity, SOD activity, and POD activity, were measured over time after 20% PEG treatment. All indexes showed dramatic changes in response to drought stress. A total of 1,190 differentially expressed genes (DEGs) were identified using RNA-seq and the most predominant were related to a number of stress-response genes and late embryogenesis abundant (LEA) proteins. DEGs were gathered into six clusters and were found to be involved in the ABA biosynthesis and signal pathway based on hierarchical clustering and GO and KEGG pathway enrichment. Transcription factors, such as NAC and bZIP, also took part in the response to drought stress. We determined an ABA-dependent and ABA-independent pathway in the regulation of drought stress in Tartary buckwheat. To the best of our knowledge, this is the first transcriptome analysis of drought stress in Tartary buckwheat, and our results provide a comprehensive gene regulatory network of this crop in response to drought stress.
A Single Surgeon’s Experience of Total Extra Peritoneal Repair Vs Transabdominal Preperitoneal Repair- A Prospective Cohort Study
Authors: Chitrambalam Tharun Ganapathy , Panicker Koshy Mathew , Sundaraj Jeyakumar , Rajasekhar Sidhu , Christopher Pradeep Joshua
Published: March 2021

Introduction: Hernia surgery has evolved over a period of 2500 years from the Bassini-Shouldice era to conventional Lichenstein’s meshplasty to the laparoscopic era. Since, inception of the laparoscopic approach 25 years ago, there were several advancements in the techniques of inguinal hernia repairs. The two most commonly practiced laparoscopic approaches are the Total Extra Peritoneal (TEP) and Transabdominal Preperitoneal (TAPP) repair. Aim: To compare the outcomes for TEP and TAPP approaches in laparoscopic inguinal hernia surgery in terms of operative time consumed, postoperative pain, duration of hospital stay, complications and recurrence rate when performed by a single surgeon. Materials and Methods: A prospective interventional cohort study was carried out among 70 patients with uncomplicated inguinal hernia. Patients were divided equally into two groups of 35 patients and underwent TAPP and TEP repairs depending on group randomisation. All surgeries were performed by the same surgeon. Factors including operative time, postoperative pain, duration of hospital stay, complications and recurrence were documented and compared for both the groups. The statistical analysis was done using Statistical Package for the Social Sciences (SPSS) software version 21. Unpaired t-test was used to compare the mean between the two groups. The p-value of <0.05 was considered to be statistically significant. Results: The mean operative time measured in minutes for TEP repair was 31.03 minutes and TAPP repair was 42.26 showing a difference of 11.23 minutes which was statistically significant (p-0.001). The mean Standard Deviation (SD) pain score at 24 hours for TEP repair was 2.43 (1.195) and TAPP repair was 3.43 (0.917). The mean (SD) pain score at 48 hours for TEP repair was 1.31 (1.051) and TAPP repair was 2.20 (0.901). The mean (SD) pain score at one week for TEP repair was 0.37 (0.690) and TAPP repair was 0.91 (0.781). The mean (SD) duration of hospital stay in TEP repair was 2.60 days (0.553) when compared to 3.49 days (0.658) in TAPP repair. All the results were statistically significant with a p-value of 0.001. Conclusion: TEP repair had superior outcomes in terms of reduction in operative time, less postoperative pain and shorter hospital stay than TAPP repair.
Bartsocas-Papas Syndrome: A Lethal Multiple Pterygium Syndrome
Authors: Mehta Sumita , Kale Ekta , Ravi Tarun Kumar , Mann Ankita , Nanda Pratibha
Published: March 2021

Bartsocas-Papas Syndrome (BPS) is a very rare autosomal recessive syndrome characterised by marked craniofacial deformities, multiple pterygia of various joints, limb and genital abnormalities. It is mostly associated with mutation in the gene encoding Receptor Interacting Serine/Threonine Kinase 4 (RIPK4) required for keratinocyte differentiation. The syndrome is generally lethal and majority of babies die in-utero or in the early neonatal period. This is a report about a neonate born with characteristic clinical features of BPS including severe craniofacial and ophthalmic abnormalities, limb deformities and multiple pterygia at popliteal, axillary and inguinal region. The baby had respiratory distress at birth and was managed conservatively on Continuous Positive Airway Pressure (CPAP)/Oxygen hood and injectable antibiotics for two weeks and then referred for further work-up to a tertiary hospital. The parents took the baby home against the advice of the treating doctors and she subsequently died after 10 days. BPS is associated with high mortality and so all efforts should be directed towards diagnosing it early antenatally when termination of pregnancy is a viable option. This is possible by having a high index of suspicion in couples with consanguineous marriages or with a positive family history.
A Case Report of Beckwith-Weidemann Syndrome: An Overgrowth Anomaly
Authors: Jindal Monika , Minhas Santosh , Sharma Monika , Singh Jaspreet
Published: March 2021

Beckwith-Wiedemann Syndrome (BWS) is an overgrowth anomaly of congenital origin that has low prevalence. However, among the congenital anomalies of overgrowth, it has high prevalence. Typical features are macroglossia, macrosomia, omphalocele and anterior abdominal wall defects. Though Genetic, but it’s mechanism of occurrence is not clear. Many researchers have found correlation between methodology of Assisted Reproductive Techniques and BWS. Future research for the improvement of the prenatal diagnostic techniques would help the multidisciplinary team to treat these congenital diseases. In the present case, the diagnosis of BWS was made by ultrasound conducted in Radiology Department after filling Preconception and Prenatal Diagnostic Techniques (PCPNDT) form in the institute at gestation of 29+6 weeks and after two days of diagnosis, unfortunately patient reported to our hospital emergency with intrauterine foetal demise.
Continuous Epidural Analgesia and Continuous Femoral Nerve Block for Postoperative Pain after Unilateral Total Knee Arthroplasty: A Prospective Cohort Study
Authors: Anupama TG , Bindu MV , Ravindran Rashmi
Published: March 2021

Introduction: Total Knee Arthroplasty (TKA) surgeries are associated with moderate to severe postoperative pain. Inadequate analgesia leads to patient distress, suboptimal knee mobilisation and complications due to delayed rehabilitation. Peripheral nerve blocks and central neuraxial techniques are in the vanguard of various analgesic strategies to minimise pain after TKA. Aim: To compare the effects of Continuous Epidural Analgesia (CEA) and Continuous Femoral Nerve Block (CFNB) on postoperative analgesia, knee rehabilitation and adverse effects after TKA surgeries. Materials and Methods: A prospective cohort study was conducted among 90 patients undergoing unilateral TKA at the Government Medical College, Kozhikode, Kerala, India. They were divided into two groups of 45 each. CEA (Group E) and CFNB (Group F) were given for postoperative pain management. Effectiveness of postoperative analgesia was measured by Numerical Rating Scale (NRS) scores at 6, 12, 24, 48 and 72 hours and also by need for rescue analgesics during the first 48 hours. Postoperative knee rehabilitation indices were measured on 1st, 2nd and 3rd Postoperative Days (POD). Incidence of adverse effects in each group was also noted. Continuous variables were analysed using students t-test, categorical variables using Chi-square test and NRS scores using Mann Whitney U test. Results: NRS scores were similar in both CEA (E) and CFNB (F) groups. On POD 1, 75.6% of group E and 71.1% of group F (p=0.630), on POD 2, 71.1% of group E and 68.9% of group F (p=0.818) and on POD 3, 62.2% of group E and 66.7% of group F (p=0.66) achieved specific rehabilitation indices. There was no statistically significant difference in pain scores, rescue analgesic requirement and rehabilitation indices between the two groups. No significant adverse effects were noted in either group. Conclusion: CFNB is as effective as continuous epidural block for postoperative analgesia and knee rehabilitation after TKA without any significant side-effects.
Benzoic Acid Based Beverages: Health Implications
Authors: Rabiu Sulaiman , Abubakar Muazu Gusau , Sahabi Danladi Mahuta , Makusidi Muhammad Aliyu , Dandare Abdullahi , Bello Jaafar Haris
Published: March 2021

Soft drinks nowadays are becoming an important part of the modern diet consumed in many communities worldwide and are available in the market virtually in the same form almost anywhere around the globe. Additives such as antioxidants and preservatives are usually added to soft drinks to increase their shelf life. Several acids such as benzoic and ascorbic acid are used in beverages to prevent oxidation and degradation of matrix.  Literature documented that combination of these preservatives in soft drinks results in benzene formation. Moreover, benzene has long been reported to inflict many public health problems. This review elucidated different health consequences such as hematological, neurological, reproductive and carcinogenic effects of exposure to benzene. Liver and kidney derangements were also reported from different epidemiological and experimental studies. Therefore, we suggest that combination of ascorbic acid and benzoic acid in beverages should be avoided by small scale and industrial manufactures. A closer monitoring of these preservatives in beverages by regulatory agencies is highly needed.