bluuebunny/crossref_metadata_2025 huggingface dataset:
Effective Teacher Professional Development for School-Based Mental Health Promotion: A Review of the Literature
Authors: Dinnen Hannah L. , Litvitskiy Nicole S. , Flaspohler Paul D.
Published: September 2024

Teachers are critically involved in the delivery of school-based mental health promotion (SMHP) interventions in school, though pre-service teacher education often leaves teachers feeling underprepared in this area. Thus, understanding how best to build teachers’ capacity for delivery through effective professional development (PD) is essential for teachers to fulfill their role as delivery agents to achieve SMHP outcomes. This systematized review focuses on identifying components of high-quality teacher PD for SMHP and examining the empirical support for these components. In a two-phase analysis, we examined the descriptive literature regarding teacher PD for SMHP to identify common elements. This resulted in the identification of components relevant to training (interactive, guided by staff input) and technical assistance (TA), including the goals (skill development, motivation, generalization/adaptation), approach (collaborative, individualized, data-driven, strengths-based), and activities (modeling, performance feedback, reflection, problem solving) involved. A second phase focused on the examination of empirical evidence for these PD components. While the empirical evidence for these components was limited, the identified components represent a current standard of practice in teacher PD for SMHP, based on the existing research. These components may provide a framework for practical use in planning teacher PD related to SMHP and for designing future research into effective capacity building in this area.
Research on Green Campus Evaluation in Cold Areas Based on AHP-BP Neural Networks
Authors: Guo Mengqi , Zhu Yiyun , Xu Aiyan
Published: September 2024

The green campus agenda is a specific manifestation of sustainable development and China’s basic strategy of developing the country through science and education. As a result of the differences in the climate environments and topographies of various places, the requisites for site planning and energy consumption by colleges and universities are different among regions, especially cold regions. However, China’s current green campus evaluation standard, GB/T 51356-2019, does not refine the evaluation indicators according to the different regions. Therefore, it is important to develop a green campus evaluation system appropriate to the region. Firstly, based on the relevant literature and standards, this paper clarifies the four evaluation criteria of campus sustainable land use, resource utilization, healthy environment, and safety. Nine first-level evaluation indicators for campuses—master planning, energy utilization, indoor environment, etc.—and twenty-one second-level evaluation indicators for campus siting—such as the use of water-saving appliances and renewable energy—were determined. Secondly, expert scoring and hierarchical analysis (AHP) were utilized to calculate the weights of the evaluation indicators by inputting the experts’ scores into the neural network model and testing the evaluation results using a back propagation neural network (BP) to finally establish a green campus evaluation model for cold regions based on an AHP-BP neural network. Finally, a university building in Xi’an, a cold region, was selected as a case study, and the errors in the green campus evaluation results were between 0.0001 and 0.001, which verifies the precision and practicability of the assessment system and the AHP-BP model. This paper’s findings serve as significant references for the improvement in assessment criteria for green campuses in the future.
Assessment of Construction Workers’ Spontaneous Mental Fatigue Based on Non-Invasive and Multimodal In-Ear EEG Sensors
Authors: Fang Xin , Li Heng , Ma Jie , Xing Xuejiao , Fu Zhibo , Antwi-Afari Maxwell Fordjour , Umer Waleed
Published: September 2024

Construction activities are often conducted in outdoor and harsh environments and involve long working hours and physical and mental labor, which can lead to significant mental fatigue among workers. This study introduces a novel and non-invasive method for monitoring and assessing mental fatigue in construction workers. Based on cognitive neuroscience theory, we analyzed the neurophysiological mapping of spontaneous mental fatigue and developed multimodal in-ear sensors specifically designed for construction workers. These sensors enable real-time and continuous integration of neurophysiological signals. A cognitive experiment was conducted to validate the proposed mental fatigue assessment method. Results demonstrated that all selected supervised classification models can accurately identify mental fatigue by using the recorded neurophysiological data, with evaluation metrics exceeding 80%. The long short-term memory model achieved an average accuracy of 92.437%. This study offers a theoretical framework and a practical approach for assessing the mental fatigue of on-site workers and provides a basis for the proactive management of occupational health and safety on construction sites.
Unveiling Digital Transformation: Analyzing Building Facility Management’s Preparedness for Transformation Using Structural Equation Modeling
Authors: Naji Khalid K. , Gunduz Murat , Al-Qahtani Abdulla
Published: September 2024

Digital transformation (DT) is revolutionizing building facility management (FM) by streamlining operations, maximizing resources, and increasing performance. FM firms prioritize DT to stay competitive as speed and efficiency become more crucial in the corporate context. Traditional FM methods like manual record-keeping and reactive maintenance cannot meet recent corporate needs. Modern technologies such as IoT, AI, digital twins, and data analytics enable real-time building asset monitoring and optimization. This paper evaluates the digital transformation readiness level index of building facility management (DTRLIBFM), which includes critical success factors for DT development, using structural equation modeling (SEM). DTRLIBFM model determines the importance of key factors that contribute to the success of digital transformation initiatives, specifically focusing on the DT readiness level index of building facility management. Expert interviews and an intensive literature review were employed to identify the critical success factors for the DTRLIFMB. The Delphi technique was employed to validate these factors with 13 highly experienced professionals, and they were subsequently appraised for significance through an online questionnaire that was circulated to industry experts. To quantitatively evaluate the interconnectedness of different elements of DTRLIFMB and establish the impact of each construct on the overall digital transformation, data from 220 participants from around the world were analyzed using (SEM). The evaluation included reliability, validity, hypothesis testing, multivariate normality, and goodness-of-fit indexes. The DTRLIBFM model, with 20 indicators in three constructs, explains how DT readiness affects a building’s digitalization importance level. The research provides governments, organizations, contractors, consultants, suppliers, subcontractors, and facility managers with a current DT index and DT roadmap for building facility management.
Evaluation and Optimization of Traditional Mountain Village Spatial Environment Performance Using Genetic and XGBoost Algorithms in the Early Design Stage—A Case Study in the Cold Regions of China
Authors: Xu Zhixin , Li Xiaoming , Sun Bo , Wen Yueming , Tang Peipei
Published: September 2024

As urbanization advances, rural construction and resource development in China encounter significant challenges, leading to the widespread adoption of standardized planning and design methods to manage increasing population pressure. These uniform approaches often prioritize economic benefits over climate adaptability and energy efficiency. This paper addresses this issue by focusing on traditional mountain villages in northern regions, particularly examining the wind and thermal environments of courtyards and street networks. This study integrates energy consumption and comfort performance analysis early in the planning and design process, utilizing Genetic and XGBoost algorithms to enhance efficiency. This study began by selecting a benchmark model based on simulations of courtyard PET (Physiological Equivalent Temperature) and MRT (mean radiant temperature). It then employed the Wallacei_X plugin, which uses the NSGA-II algorithm for multi-objective genetic optimization (MOGO) to optimize five energy consumption and comfort objectives. The resulting solutions were trained in the Scikit-learn machine learning platform. After comparing machine learning models like RandomForest and XGBoost, the highest-performing XGBoost model was selected for further training. Validation shows that the XGBoost model achieves an average accuracy of over 80% in predicting courtyard performance. In the project’s validation phase, the overall street network framework of the block was first adjusted based on street performance prediction models and related design strategies. The optimized model prototype was then integrated into the planning scheme according to functional requirements. After repeated validation and adjustments, the performance prediction of the village planning scheme was conducted. The calculations indicate that the optimized planning scheme improves overall performance by 36% compared with the original baseline. In conclusion, this study aimed to integrate performance assessment and machine learning algorithms into the decision-making process for optimizing traditional village environments, offering new approaches for sustainable rural development.
Spatial Analysis with Detailed Indoor Building Models for Emergency Services
Authors: Cheng Min-Lung , Tsai Fuan , Teo Tee-Ann
Published: September 2024

This paper presents a systematic approach to perform spatial analysis with detailed indoor building models for emergency service decision supports. To achieve a more realistic spatial application, this research integrates three-dimensional (3D) indoor building models and their attributes to simulate an emergency evacuation scenario. Indoor building models of a complicated train station with different levels of detail are generated from two-dimensional (2D) floor plans and Building Information Model (BIM) datasets. In addition to the 3D building models, spatial and non-spatial attributes are also associated with the created building models and the objects within them. The ant colony optimization (ACO) algorithm is modified to analyze the indoor building models for emergency service decision support applications. The detailed indoor models and the proposed spatial analysis algorithms are tested in simulated emergency evacuation scenarios to select the best routes during emergency services. The experimental results demonstrate that the proposed system is helpful for selecting the optimal route with the least cost at varying time stamps. Together with the developed spatial analysis framework, they have a great potential for effective decision support during emergency situations.
Pleiotropic Effects of Peroxisome Proliferator-Activated Receptor Alpha and Gamma Agonists on Myocardial Damage: Molecular Mechanisms and Clinical Evidence—A Narrative Review
Authors: Rubio-Ruíz María Esther , Plata-Corona Juan Carlos , Soria-Castro Elizabeth , Díaz-Juárez Julieta Anabell , Sánchez-Aguilar María
Published: September 2024

Cardiovascular diseases remain the leading cause of death in the world, and that is why finding an effective and multi-functional treatment alternative to combat these diseases has become more important. Fibrates and thiazolidinediones, peroxisome proliferator-activated receptors alpha and gamma are the pharmacological therapies used to treat dyslipidemia and type 2 diabetes, respectively. New mechanisms of action of these drugs have been found, demonstrating their pleiotropic effects, which contribute to preserving the heart by reducing or even preventing myocardial damage. Here, we review the mechanisms underlying the cardioprotective effects of PPAR agonists and regulating morphological and physiological heart alterations (metabolic flexibility, mitochondrial damage, apoptosis, structural remodeling, and inflammation). Moreover, clinical evidence regarding the cardioprotective effect of PPAR agonists is also addressed.
E-Selectin and Asymmetric Dimethylarginine Levels in Adult Cyanotic Congenital Heart Disease: Their Relation to Biochemical Parameters, Vascular Function, and Clinical Status
Authors: Nartowicz Sonia Alicja , Szczepaniak-Chicheł Ludwina , Lipski Dawid , Miechowicz Izabela , Bartczak-Rutkowska Agnieszka , Gabriel Marcin , Lesiak Maciej , Trojnarska Olga
Published: September 2024

Background and Aim: Patients with cyanosis secondary to congenital heart disease (CHD) are characterized by erythrocytosis and increased blood viscosity, which contribute to endothelial dysfunction, increased arterial stiffness, and impaired vascular function, which may affect the final clinical presentation. Asymmetric dimethylarginine (ADMA) and e-selectin (e-sel) are valuable biomarkers for endothelial and vascular dysfunction. Their concentration levels in blood serum have the potential to be an accessible tool that reflects the severity of the disease. We aimed to assess e-sel and ADMA levels and their relationship with the clinical status and endothelial and vascular function. Methods: A cross-sectional study, including 36 adult CHD cyanotic patients [(17 males) (42.3 ± 16.3 years)] with an arterial blood oxygen saturation less than 92% and 20 healthy controls [(10 males) (38.2 ± 8.5 years)], was performed. All the patients underwent a clinical examination, blood testing, and cardiopulmonary tests. Their endothelial function was assessed using the intima media thickness and flow-mediated dilatation. Vascular function, using applanation tonometry methods, was determined using the aortic systolic pressure, aortic pulse pressure, augmentation pressure, augmentation index, pulse pressure amplification, and pulse wave velocity. Results: The concentrations of e-sel and ADMA were significantly higher in the patients with CHD. The E-sel levels correlated positively with red blood cells, hemoglobin concentration, hematocrit, and augmentation pressure; they correlated negatively with blood oxygen saturation, the forced expiratory one-second volume, forced vital capacity, and oxygen uptake. The ADMA levels were found to correlate only with age. Conclusions: The E-sel level, unlike ADMA concentration, reflects the severity of erythrocytosis and hypoxia and, thus, the physical status of patients with cyanotic CHD.
Context of Atropine Adherence in Preschool Children with Early-Onset Myopia: A Qualitative Study
Authors: Ho Ciao-Lin
Published: September 2024

The use of atropine is currently one of the most effective methods used to prevent myopia progression. The purpose of this study was to investigate atropine adherence in preschool children with myopia, to explain the context of treatment through caregivers, and to identify barriers and facilitators of using atropine. We conducted in-depth interviews with 60 caregivers of children (parents, kindergarten teachers and nurses) in four different areas ranging from large cities to rural areas in Taiwan. Based on the social ecological theory model, the recorded text was systematically analyzed, extracted, edited and indexed by NVivo 12 Plus. After interviewing caregivers, we determined the barriers and facilitators at the four levels of influence (children, parents, school, and hospital and society). Barriers included the side effects, parental neglect, lack of understanding of long-term drug use, lack of conducive environment, and lack of friendly medical services. Facilitators included overcoming side effects, parental responsibility, myopia progression on treatment adherence, teacher support, management by nurses, navigation by ophthalmologists, and model learning. Hence, establishing a social support network, discussing the experience of individualized drug use in preschool children, and establishing a friendly medical intervention strategy can raise awareness among parents regarding myopia, and improve atropine adherence in preschool children.
Novel Mutations in AKT1 Gene in Prostate Cancer Patients in Jordan
Authors: Alasmar Ala’a , Al-Alami Zina , Zein Sima , Al-Smadi Asmaa , Al Bashir Samir , Alorjani Mohammed S. , Al-Zoubi Raed M. , Al Zoubi Mazhar
Published: September 2024

The AKT1 oncogene is related to various cancers due to its critical role in the PIC3CA/AKT1 pathway; however, most of the studies screened the hotspot mutation AKT1 (E17K) with various incidences. Low frequency or lack of AKT1 (E17K) mutation was reported in prostate cancer (PC) patients. This study aims to explore genetic alterations in the AKT1 PH domain by extending the sequencing to include AKT1 gene exons 3 and 4. Genomic DNA was extracted from 84 Formalin-Fixed Paraffin-Embedded samples of PC patients in Jordan, and then subjected to PCR and sequencing for the targeted exons. This study revealed the presence of two novel mutations (N53Y and Q59K) and a high frequency of mutations in exon 4, with a lack of mutations in the E17K hotspot. Nine missense and two synonymous mutations were detected in exon 4 (Phe27Tyr, Phe27Leu, Ala58Thr, Ser56Phe, Arg41Trp, Phe35Leu, Asp32Glu, Phe35Tyr, and Gln43Lys) and (Ser56 and Glu40), respectively. Two synonymous mutations were detected in exon 3 (Leu12 and Ser2). It is concluded that there is a high frequency of AKT1 mutation in PC patients in Jordan with two novel missense mutations in the Pleckstrin homology (PH) domain. E17K hotspot mutation was not detected in any tested samples, which underlined the significant role of mutations in other AKT1 exons in PC development.
Dexamethasone Impairs ATP Production and Mitochondrial Performance in Human Trabecular Meshwork Cells
Authors: Kennedy Shane , Williams Clayton , Tsaturian Emily , Morgan Joshua T.
Published: September 2024

Mitochondrial damage occurs in human trabecular meshwork (HTM) cells as a result of normal aging and in open angle glaucoma. Using an HTM cell model, we quantified mitochondrial function and ATP generation rates after dexamethasone (Dex) and TGF-β2 treatments, frequently used as in vitro models of glaucoma. Primary HTM cells were assayed for metabolic function using a Seahorse XFp Analyzer. We additionally assessed the mitochondrial copy number and the expression of transcripts associated with mitochondrial biogenesis and oxidative stress regulation. Cells treated with Dex, but not TGF-β2, exhibited a significant decrease in total ATP production and ATP from oxidative phosphorylation relative to that of the control. Dex treatment also resulted in significant decreases in maximal respiration, ATP-linked O2 consumption, and non-mitochondrial O2 consumption. We did not observe significant changes in the level of mitochondrial genomes or mRNA transcripts of genes involved in mitochondrial biogenesis and oxidative stress regulation. Decreased mitochondrial performance and ATP production are consistent with the results of prior studies identifying the effects of Dex on multiple cell types, including HTM cells. Our results are also consistent with in vivo evidence of mitochondrial damage in open-angle glaucoma. Overall, these results demonstrate a decrease in mitochondrial performance in Dex-induced glaucomatous models in vitro, meriting further investigation.
Glioblastoma Tumor Microenvironment: An Important Modulator for Tumoral Progression and Therapy Resistance
Authors: Tataranu Ligia Gabriela , Turliuc Serban , Kamel Amira , Rizea Radu Eugen , Dricu Anica , Staicu Georgiana-Adeline , Baloi Stefania Carina , Rodriguez Silvia Mara Baez , Manole Andrada Ioana Maria
Published: September 2024

The race to find an effective treatment for glioblastoma (GBM) remains a critical topic, because of its high aggressivity and impact on survival and the quality of life. Currently, due to GBM’s high heterogeneity, the conventional treatment success rate and response to therapy are relatively low, with a median survival rate of less than 20 months. A new point of view can be provided by the comprehension of the tumor microenvironment (TME) in pursuance of the development of new therapeutic strategies to aim for a longer survival rate with an improved quality of life and longer disease-free interval (DFI). The main components of the GBM TME are represented by the extracellular matrix (ECM), glioma cells and glioma stem cells (GSCs), immune cells (microglia, macrophages, neutrophils, lymphocytes), neuronal cells, all of them having dynamic interactions and being able to influence the tumoral growth, progression, and drug resistance thus being a potential therapeutic target. This paper will review the latest research on the GBM TME and the potential therapeutic targets to form an up-to-date strategy.
Exercise-Induced Shear Stress Drives mRNA Translation In Vitro
Authors: Conde Daniel , Garcia Mario A. , Gomez Manuel , Gurovich Alvaro N.
Published: September 2024

The vascular endothelium is the first line of defense to prevent cardiovascular disease. Its optimal functioning and health are maintained by the interaction of the proteins—endothelial nitric oxide synthase (eNOS), sirtuin 1 (SIRT1), and endothelin 1 (ET1)—and the genes that encode them—NOS3, SIRT1, and EDN1, respectively. Aerobic exercise improves endothelial function by allegedly increasing endothelial shear stress (ESS). However, there are no current data exploring the acute effects of specific exercise-induced ESS intensities on these regulatory proteins and genes that are associated with endothelial function. The purpose of this study was to assess the acute changes in endothelial proteins and gene expression after exposure to low-, moderate-, and high-intensity exercise-induced ESS. Human umbilical vein endothelial cells (HUVECs) were exposed to resting ESS (18 dynes/cm2, 60 pulses per minute (PPM)), low ESS (35 dynes/cm2, 100 PPM), moderate ESS (50 dynes/cm2, 120 PPM), and high ESS (70 dynes/cm2, 150 PPM). Protein and gene expression were quantified by fluorescent Western blot and RTqPCR, respectively. All exercise conditions showed an increase in eNOS and SIRT1 expression and a decrease in NOS3 and SIRT1 gene expression when compared to resting conditions. In addition, there was no expression of ET1 and an increase in EDN1 gene expression when compared to resting conditions. These results show that (1) exercise-induced ESS increases the expressions of vascular protective proteins and (2) there is an inverse relationship between the proteins and their encoding genes immediately after exercise-induced ESS, suggesting that exercise has a previously unexplored translational role catalyzing mRNA to proteins.
Gibberellins Play an Essential Role in the Bud Growth of Petunia hybrida
Authors: Deng Jichu , Deng Xinyi , Yao Huanyu , Ji Shunhua , Dong Lili
Published: September 2024

This study delves into the role of gibberellin (GA) in governing plant branch development, a process that remains incompletely understood. Through a combination of exogenous hormone treatment, gene expression analysis, and transgenic phenotype investigations, the impact of GA on petunia’s branch development was explored. The results showed that GA3 alone did not directly induce axillary bud germination. However, paclobutrazol (PAC), an inhibitor of GA synthesis, effectively inhibited bud growth. Interestingly, the simultaneous application of GA3 and 6-BA significantly promoted bud growth in both intact and decapitated plants compared to using 6-BA alone. Moreover, this study observed a significant downregulation of GA synthesis genes, including GA20ox1, GA20ox2, GA20ox3, GA3ox1, and CPS1, alongside an upregulation of GA degradation genes such as GA2ox2, GA2ox4, and GA2ox8. The expression of GA signal transduction gene GID1 and GA response factor RGA was found to be upregulated. Notably, the PhGID1 gene, spanning 1029 bp and encoding 342 amino acids, exhibited higher expression in buds and the lowest expression in leaves. The overexpression of PhGID1 in Arabidopsis resulted in a noteworthy rise in the number of branches. This study highlights the crucial role of GA in bud germination and growth and the positive regulatory function of GA signaling in shoot branching processes.
Development and Analysis of a Global Floating Wind Levelised Cost of Energy Map
Authors: Vilajuana Llorente Sergi , Rapha José Ignacio , Domínguez-García José Luis
Published: September 2024

Floating offshore wind (FOW) is rapidly gaining interest due to its large potential. In this regard, it is of special interest to determine the best locations for its installation. One of the main aspects when evaluating the feasibility of a project is the levelised cost of energy (LCOE), but there are many variables to consider when calculating it for FOW, and plenty of them are hard to find when the scope is all the suitable areas worldwide. This paper presents the calculation and analysis of the global LCOE with particular focus on the best countries and territories from an economic point of view, considering four types of platforms: semi-submersible, barge, spar, and tension leg platform (TLP). The model takes into account, on the one hand, wind data, average significant wave height, and distance to shore for an accurate calculation of delivered energy to the onshore substation and, on the other hand, bathymetry, distances, and existing data from projects to find appropriate functions for each cost with regression models (e.g., manufacturing, installation, operation and maintenance (O&M), and decommissioning costs). Its results can be used to assess the potential areas around the world and identify the countries and territories with the greatest opportunities regarding FOW. The lowest LCOE values, i.e., the optimal results, correspond to areas where wind resources are more abundant and the main variables of the site affecting the costs (water depth, average significant wave height, distance to shore, and distance to port) are as low as possible. These areas include the border between Venezuela and Colombia, the Canary Islands, Peru, the border between Western Sahara and Mauritania, Egypt, and the southernmost part of Argentina, with LCOEs around 90 €/MWh. Moreover, there are many areas in the range of 100–130 €/MWh.
A Selective, Efficient, Facile, and Reusable Natural Clay/Metal Organic Framework as a Promising Adsorbent for the Removal of Drug Residue and Heavy Metal Ions
Authors: Abdelazeem Rania , Younes Heba A. , Eldin Zienab E. , Allam Ahmed A. , Rudayni Hassan Ahmed , Othman Sarah I. , Farghali Ahmed A. , Mahmoud Hamada M. , Mahmoud Rehab
Published: September 2024

It is imperative to eliminate heavy metals and pharmaceutical residual pollutants from wastewater to reduce their detrimental effects on the environment. In this work, natural zeolite and a 2-amino terephthalic acid-based multi-metallic organic framework were used to create a new composite that can be utilized as an adsorbent for cadmium and safinamide. The adsorption study was examined in a variety of settings (pH, adsorbent dosage, pollutant concentration, and time). Moreover, Zeta potential, BET, SEM, FTIR, XRD, and SEM measurements were used to characterize the adsorbents. The adsorption process was confirmed using FTIR, XRD, and SEM analysis. Various nonlinear adsorption isotherm models were applied to adsorption results. The results showed a significantly better adsorption ability for safinamide and cadmium using zeolite/MOF compared to zeolite. Adsorption kinetics were represented by five models: pseudo first-order, pseudo second-order, intraparticle diffusion, mixed first- and second-order, and the Avrami model. Regarding both adsorbent substances, safinamide adsorption was best represented by the intraparticle diffusion model. In contrast, the pseudo second-order and intraparticle diffusion models for zeolite and zeolite/MOF, respectively, better fit the experimental results in the case of cadmium adsorption. The thermodynamic parameters ΔH°, ΔS°, and ΔG° were investigated through temperature tests carried out at 25, 35, 45, and 55 °C. Exothermic and spontaneous adsorption processes were demonstrated by the computed values. The study of adsorbent regeneration involved the use of several chemical solvents. The DMSO solvent was shown to have the highest adsorbent regeneration method efficiency at 63%. Safinamide elimination was lessened by organic interfering species like cefixime and humic acid compared to inorganic species like chloride, sulphate, and nitrate, most likely as a result of intense competition for the few available active sites. Using zeolite/MOF nanocomposite, the percentage of safinamide removed from spiked real water samples (tap water, Nile River water, and groundwater samples) was 48.80%, 64.30%, and 44.44%, respectively. Based on cytotoxicity results, the highest percentages of cell viability for zeolite and zeolite/MOF at 24 h were 83% and 81%, respectively, in comparison to untreated controls. According to these results, zeolite and zeolite/MOF composites can be used as effective adsorbents for these pollutants in wastewater.
Predicting Student Performance in Introductory Programming Courses
Authors: Pires João P. J. , Brito Correia Fernanda , Gomes Anabela , Borges Ana Rosa , Bernardino Jorge
Published: September 2024

The importance of accurately predicting student performance in education, especially in the challenging curricular unit of Introductory Programming, cannot be overstated. As institutions struggle with high failure rates and look for solutions to improve the learning experience, the need for effective prediction methods becomes critical. This study aims to conduct a systematic review of the literature on methods for predicting student performance in higher education, specifically in Introductory Programming, focusing on machine learning algorithms. Through this study, we not only present different applicable algorithms but also evaluate their performance, using identified metrics and considering the applicability in the educational context, specifically in higher education and in Introductory Programming. The results obtained through this study allowed us to identify trends in the literature, such as which machine learning algorithms were most applied in the context of predicting students’ performance in Introductory Programming in higher education, as well as which evaluation metrics and datasets are usually used.
Characterizing Normal Upper Extremity Lymphatic Flow with 99mTc In-House Dextran: A Retrospective Study
Authors: Katiyarangsan Wiroj , Charoenphun Putthiporn , Chuamsaamarkkee Krisanat , Musikarat Suchawadee , Kiranantawat Kidakorn , Sakulpisuti Chaninart , Thamnirat Kanungnij , Kositwattanarerk Arpakorn , Sritara Chanika , Chamroonrat Wichana
Published: September 2024

Lymphoscintigraphy evaluates the lymphatic system using radiocolloid compounds like 99mTc-sulfur colloid and 99mTc-nanocolloid, which vary in particle size and distribution timing. A local in-house Dextran kit (15–40 nm) was developed in 2005 and began clinical use in 2008 to localize sentinel lymph nodes; diagnose lymphedema; and detect lymphatic leakage. The normal drainage pattern remains unexplored. We retrospectively analyzed 84 upper extremity lymphoscintigraphies from 2008 to 2021. 99mTc in-house Dextran was intradermally injected into both hands, followed by whole-body imaging at specified intervals (≤15 min; 16–30 min; 31–45 min; 46–60 min), with some receiving delayed imaging. Visual and quantitative analyses recorded axillary and forearm lymph nodes and liver, kidney, and urinary bladder activity. Results showed 92% (77/84) upper extremity lymphatic tract visualization within 45 min. Axillary node detection rates increased from 46% (≤15 min) to 86% (46–60 min). Delayed imaging further revealed nodes. Epitrochlear or brachial node visualization was rare (4%, 3/84). Hepatic, renal, and urinary bladder activity was noted in 54%, 71%, and 93% at 1 h, respectively. The axillary node uptake ratio was minimal (<2.5% of injection site activity; median 0.33%). This study characterizes normal upper extremity lymphatic drainage using 99mTc in-house Dextran, offering insights into its clinical application
Comparing New Smartphone-Connected Handheld Ultrasound Device vs. Traditional Ultrasound in Vitreo-Retinal Disease Diagnosis
Authors: Rubegni Giovanni , Zeppieri Marco , Russo Andrea , Castellino Niccolò , Fruschelli Mario , Hadjistilianou Theodora , Tognetti Linda , Orione Matteo , Lanzafame Luca , Gagliano Caterina , Cartocci Alessandra , Tosi Gian Marco , Avitabile Teresio
Published: September 2024

(1) Background: Ocular emergencies account for 1.5–3% of emergency department (ED) visits and require urgent diagnosis to prevent serious complications. Ultrasonography is a crucial, non-invasive diagnostic tool for these conditions but traditionally lacks portability and integration with modern electronic smart devices. The purpose of this study was to assess the accuracy and performance of a new handheld ultrasound device in comparison to a conventional cart-based sonographic machine in patients attending to the ED for vitreo-retinal diseases. (2) Methods: three specialists in ophthalmology, with at least 4-year experience in vitreo-retinal diseases and eye ultrasound, evaluated images of 50 eyes with both portable and traditional ultrasound probes. Each specialist made the diagnosis based on the images captured with both probes and then rated their overall image quality and confidence of diagnosis with a five-point Likert scale. The concordance of diagnosis between the two probes was evaluated. (3) Results: The sample comprised 42 patients. Twenty (40%) healthy eyes and thirty eyes with the following vitreo-retinal interface conditions were examined: 12 retinal detachment (24%), 8 vitreous hemorrhage (16%), and 10 posterior vitreous detachment (20%). The overall accuracy of the two devices appeared to be comparable (70.7% vs. 69.3%). The Butterfly iQ+ probe showed similar sensitivity in retinal detachment diagnosis (91.7% vs. 94.4% of the Accutome B-scan Pro), while it showed poor performance in diagnosing posterior vitreous detachment (sensitivity = 27.2%); (4) Conclusions: The Butterfly iQ+ device demonstrated high sensitivity in the diagnosis of retinal detachment. Significant adjustments are still needed to improve the resolution of the vitreous body.
Cryoprobe Placement Using Electromagnetic Navigation System (IMACTIS® CT-Navigation™) for Cryoablation Treatment of Upper Kidney Pole Lesions and Adrenal Metastases: Experience from a Single-Center, 4-Year Study
Authors: Michailidis A. , Kosmoliaptsis P. , Dimou G. , Mingou G. , Zlika S. , Giankoulof C. , Galanis S. , Petsatodis E.
Published: September 2024

The aim of this study is to evaluate the safety and efficacy of the use of the IMACTIS® CT-Navigation™-electromagnetic navigation system (EMNS) in cryoablation CT-guided procedures under local anesthesia for the treatment of upper kidney pole and adrenal lesions. We conducted a retrospective analysis of patients with upper kidney pole lesions and adrenal metastases who underwent cryoablation using the IMACTIS-CT®-EMNS between January 2019 and April 2023. The EMNS was used to guide the placement of the cryoprobes with CT guidance under local anesthesia. The primary outcome was technical success, defined as the successful placement of the cryoprobes in the target lesion. A total of 31 patients were studied, of whom, 25 patients were treated with cryoablation for upper pole kidney masses, and 6 patients underwent the cryoablation of adrenal metastases during the study period. The mean age was 60 years (range, 36–82 years), and 21 patients were male. All the upper kidney pole lesions were renal cell carcinomas, and regarding adrenal metastases, the primary cancer sites were the lungs (n = 3), breast (n = 2), and the colon (n = 1). The median size of the lesions was 3,8 cm (range, 1.5–5 cm). All procedures were technically successful, with the cryoprobes accurately placed in the target lesions under CT guidance using the EMNS, avoiding the penetration of any other organs using an oblique trajectory. No major complications were reported, and local tumor control was achieved in all cases. Our initial experience using the EMNS for cryoprobe placement during CT-guided interventional procedures under local anesthesia for the cryoablation treatment of upper pole kidney lesions and adrenal metastases showed that it is safe and effective.
In Vitro Evaluation of Sodium Hypochlorite, Chlorhexidine, Propolis, and Calcium Hydroxide Effect on Lipoteichoic-Acid-Induced Proinflammatory Cytokines Production
Authors: de Oliveira Luciane Dias , de Carvalho Lara Steffany , Xavier Ana Claudia Carvalho , de Oliveira Felipe Eduardo , Leão Mariella Vieira Pereira , Diamantino Mariana Gadelho Gimenez , Khoury Rayana Duarte , Valera Marcia Carneiro , Carvalho Cláudio Antonio Talge , Abu Hasna Amjad
Published: September 2024

This study aimed to evaluate the effects of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and the glycolic extract of propolis (GEP) as endodontic irrigants and of calcium hydroxide [Ca(OH)2], CHX, or Ca(OH)2 + CHX as intracanal medications on the capacity of the lipoteichoic acid (LTA) of Enterococcus faecalis in macrophages’ proinflammatory cytokines production. Freshly extracted 108 human single-rooted teeth were used in this study. The LTA of E. faecalis was standardized in double-distilled pyrogen-free water (250 µg/mL) and inoculated into the specimens subdivided into nine subgroups (n = 12). Cultures of murine macrophages (RAW 264.7) were treated with 30 µL of each sample collected from root canals and incubated (37 °C, 5% CO2) for 24 h. Lastly, anti-TNF-α, anti-IL-6, anti-IP-10, anti-MIP-1α, anti-G-CSF, and anti-IL-1β DuoSet kits were used to perform an ELISA assay. Data were analyzed using one-way ANOVA and Tukey test (p ≥ 0.05). It was found that 1% NaOCl was the most effective irrigant in reducing the capacity of LTA in cytokines production, followed by 12% GEP and 2% CHX, respectively. Ca(OH)2 + CHX presented the best results when associated with NaOCl or GEP. Thus, NaOCl or GEP associated with Ca(OH)2 + CHX were effective in reducing the capacity of LTA in different macrophages pro-inflammatory cytokines production.
Runway-Free Recovery Methods for Fixed-Wing UAVs: A Comprehensive Review
Authors: Liu Yunxiao , Wang Yiming , Li Han , Ai Jianliang
Published: September 2024

Fixed-wing unmanned aerial vehicles (UAVs) have the advantages of long endurance and fast flight speed and are widely used in surveying, mapping, monitoring, and defense fields. However, its conventional take-off and landing methods require runway support. Achieving runway-free recovery is necessary for expanding the application of fixed-wing UAVs. This research comprehensively reviews the various techniques and scenarios of runway-free recovery of fixed-wing UAVs and summarizes the key technologies. The above methods cover parachute recovery, net recovery, rope recovery, SideArm recovery, deep stall recovery, towed drogue docking recovery, and robotic arm recovery methods within runway-free recovery. Finally, this research discusses the future research directions of runway-free recovery.
Computational Thinking and Modeling: A Quasi-Experimental Study of Learning Transfer
Authors: Musaeus Line Have , Musaeus Peter
Published: September 2024

This quasi-experimental study investigated the impact of computational learning activities on high school students’ computational thinking (CT) and computational modeling (CM) skills. High school students (n = 90) aged 16 to 19 engaged in activities using computer models versus textbook-based models in mathematics and social science. The results indicated that students using computer models showed significant improvements in CT and CM skills compared to their peers in conventional learning settings. However, a potential ceiling effect in the CT assessments suggests that the test may not fully capture the extent of skill development. These findings highlight the importance of integrating computational learning activities in education, as they enhance students’ abilities to apply these skills beyond the classroom.
Entrepreneurial Intentions: Entrepreneurship Education Programs, Cognitive Motivational Factors of Planned Behavior, and Business Incubation Centers
Authors: Anjum Temoor , Díaz Tautiva Julián Andrés , Zaheer Muhammad Asif , Heidler Petra
Published: September 2024

Previous studies have explored the factors influencing entrepreneurial intentions (EIs), primarily focusing on personality traits and various psychological aspects. This study, however, investigates external factors, such as entrepreneurship education programs (EEPs), cognitive motivational factors associated with the Theory of Planned Behavior (TPB), and the impact of business incubation centers (BICs), as moderators of EIs. The research involved 458 respondents from diverse higher education institutions in Asia. Our findings indicate that EEPs and BICs at universities positively and significantly affect students’ EIs. Additionally, the cognitive factors linked to TPB demonstrate a positive and significant direct effect on EIs while also acting as mediators between EEPs and EIs. These findings underscore the importance of adopting a multilevel perspective in designing and implementing EEPs and BICs to better comprehend the determinants of EIs. Our study provides valuable insights for university administrators, policymakers, and entrepreneurship instructors in developing countries to improve the university entrepreneurial ecosystem by creating cohesive programs and supportive institutions. Moreover, the results can serve as encouragement for individuals embarking on an entrepreneurial journey.
Parents’ and Children’s Emotional Well-Being and Language Beliefs in Heritage Bilingual Families
Authors: Bonifacci Paola , Borghetti Claudia , Cangelosi Martina
Published: September 2024

The present study aimed to examine how parents’ psychological characteristics and positive beliefs about multilingualism predict children’s emotional well-being in 51 multilingual families with an immigrant background. Parents were interviewed to assess their beliefs about multilingualism and completed a battery of questionnaires assessing depression, anxiety, psychological distress, parental competence, quality of life, and acculturative stress. They also completed the Strengths and Difficulties Questionnaire (SDQ), which assessed their children’s socio-emotional and behavioral characteristics. The results from regression analyses showed that parents’ depressive symptoms were significant concurrent predictors of children’s conduct problems. In contrast, higher acculturation stress was associated with more emotional problems and better prosociality in children, although the stronger predictor for the latter variable was parents’ self-efficacy. Positive beliefs about bilingualism were not related to children’s well-being. The discussion highlights the importance of targeting parents’ depressive traits and acculturation stress as possible risk factors for children’s emotional and behavioral problems. Conversely, fostering parental self-efficacy may promote children’s prosociality.
Sustainability of Automated Manufacturing Systems with Resources by Means of Their Deadlock Prevention
Authors: Čapkovič František
Published: September 2024

This paper is devoted to Petri net (PN)-based models of automated manufacturing systems (AMSs) with resources in order to prevent deadlocks in them. Their sustainability can be seen as the result of their deadlock freeness, leading to correct and fluent production, because AMSs with deadlocks work neither correctly nor fluently, need reconstruction and cause downtime in production. The paradigm of such PN models, S3PRs (systems of simple sequential processes with resources), is well known from the deadlock prevention point of view. Here, an extended S3PR (ES3PR) will be explored, with respect to its modelling and deadlock prevention. While in the case of S3PRs, ordinary Petri nets (OPNs) are used for these aims, here, for ES3PRs, generalized Petri nets (GPNs) are used. The reason for such a procedure is the possible presence of multiplex-directed arcs in the structure of PN models of AMSs. The significant alternation is that while, in the former case, the elementary siphons and dependent ones are sufficient for supervisor synthesis, here, in the later case, the GPNs and their siphons have to satisfy the max cs property.
The Method of Auxiliary Sources (MAS) in Computational Electromagnetics: A Comprehensive Review of Advancements over the Past Two Decades
Authors: Papakanellos Panagiotis J. , Tsitsas Nikolaos L. , Anastassiu Hristos T.
Published: September 2024

This paper presents a comprehensive review of research conducted on the Method of Auxiliary Sources (MAS) over a period of the last 22 years, i.e., since the last up-to-date survey was published. MAS is a very attractive numerical technique due to its simple algorithmic structure and the generally low computational cost it requires in terms of memory and CPU time; this is why it has been applied to a vast variety of cases, as concluded by the long citations list included. After a short introduction summarizing the fundamental concepts of the method, references since 2002 are categorized, briefly described, and commented on. This work is intended to assist every researcher who is involved in MAS computations, providing an exhaustive, to the best of the authors’ knowledge, list of related publications.
Station for Tuning and Testing Digital Twin in Hydraulic Actuator Control Systems under Programmable Load—Methodology, Design, and Tests
Authors: Ćwikła Grzegorz , Szewczyk Mirosław
Published: September 2024

This article presents the methodology and process of the modeling, designing, and testing of a research station enabling the identification, tuning, and verification of Digital Twin (DT) in control systems in power hydraulics. The concept of the station is presented, the main part of which is a subsystem forcing a dynamic, variable load using a hydraulic actuator controlled by a proportional valve, together with data acquisition and processing systems and software. The load application subsystem can subject the tested power hydraulic system, usually consisting of an actuator with its own control system, to controlled dynamic loads, which allows for the determination of its characteristics and tuning of the DT. This article describes the electro-hydraulic elements used to adjust the position of the actuators and the designed hydraulic and electrical diagrams of the station. The process of identifying, modeling, and selecting a controller for a subsystem simulating an external load is presented. The test station is built and tested. The identification, modeling, and tuning of DTs, for example, actuators and controllers, are described. A satisfactory convergence of the simulation and modeling results with the operation of the real system is achieved, which allows the obtaining of a reliable DT for actuator control systems operating under variable load.