bluuebunny/crossref_metadata_2025 huggingface dataset:
Extensive Inhibitory Gating of Viscerosensory Signals by a Sparse Network of Somatostatin Neurons
Authors: Thek Kimberly R. , Ong Sarah J.M. , Carter David C. , Bassi Jaspreet K. , Allen Andrew M. , McDougall Stuart J.
Published: August 2019

Integration and modulation of primary afferent sensory information begins at the first terminating sites within the CNS, where central inhibitory circuits play an integral role. Viscerosensory information is conveyed to the nucleus of the solitary tract (NTS) where it initiates neuroendocrine, behavioral, and autonomic reflex responses that ensure optimal internal organ function. This excitatory input is modulated by diverse, local inhibitory interneurons, whose functions are not clearly understood. Here we show that, in male rats, 65% of somatostatin-expressing (SST) NTS neurons also express GAD67, supporting their likely role as inhibitory interneurons. Using whole-cell recordings of NTS neurons, from horizontal brainstem slices of male and female SST-yellow fluorescent protein (YFP) and SST-channelrhodopsin 2 (ChR2)-YFP mice, we quantified the impact of SST-NTS neurons on viscerosensory processing. Light-evoked excitatory photocurrents were reliably obtained from SST-ChR2-YFP neurons (n= 16) and the stimulation–response characteristics determined. Most SST neurons (57%) received direct input from solitary tract (ST) afferents, indicating that they form part of a feedforward circuit. All recorded SST-negative NTS neurons (n= 72) received SST-ChR2 input. ChR2-evoked PSCs were largely inhibitory and, in contrast to previous reports, were mediated by both GABA and glycine. When timed to coincide, the ChR2-activated SST input suppressed ST-evoked action potentials at second-order NTS neurons, demonstrating strong modulation of primary viscerosensory input. These data indicate that the SST inhibitory network innervates broadly within the NTS, with the potential to gate viscerosensory input to powerfully alter autonomic reflex function and other behaviors.

SIGNIFICANCE STATEMENTSensory afferent input is modulated according to state. For example the baroreflex is altered during a stress response or exercise, but the basic mechanisms underpinning this sensory modulation are not fully understood in any sensory system. Here we demonstrate that the neuronal processing of viscerosensory information begins with synaptic gating at the first central synapse with second-order neurons in the NTS. These data reveal that the somatostatin subclass of inhibitory interneurons are driven by visceral sensory input to play a major role in gating viscerosensory signals, placing them within a feedforward circuit within the NTS.
Detecting a Fungal Pathogen in Its Natural Habitat: The Case of Valley Fever
Authors: Valenzuela Alex H. , Mullins Erica L. , Lauer Antje
Published: August 2019

Valley fever, a disease caused by the soilborne fungal pathogen Coccidioides spp., is on the rise in the southwestern United States and is suspected of expanding its habitat in response to climate change. Many people residing in endemic areas are unaware of the risk of contracting coccidioidomycosis by inhaling fugitive dust that may contain dormant arthroconidia of this fungus. In an effort to teach students about the ongoing epidemic of valley fever and reduce incidence of the disease through education, we developed an inquiry-based, multi-focus laboratory exercise that (1) increases awareness of valley fever incidence, disease symptoms, and ongoing efforts of disease prevention; (2) teaches about the pathogen's ecology; and (3) familiarizes students with molecular techniques targeting pathogen identification. This laboratory exercise uses polymerase chain reaction to detect Coccidioides spp. in DNA extracts from soil samples collected by students across different soil environments. Additionally, this exercise will teach students how to use publicly available data to investigate disease incidence over time and characterize soils the pathogen may inhabit.
The Sound of Music & Its Effect on Biological Systems: Project-Based Learning Tapping into Adolescents' Interests
Authors: De Beer Josef
Published: August 2019

Science education often fails to address the actual range of adolescents' interests. One such interest is music. Research shows that young people devote large amounts of time and money to music. By tapping into students' interest in music, affective outcomes can be achieved in the biology classroom. This article describes a project-based learning activity that studies the influence of music on seed germination. Part of the student project is to conduct a literature search on the influence of music on plants, and possibly also on people (its biological, psychological, and social effects). The project is contextualized in the indigenous practice of making music while planting crops. There is a growing body of literature suggesting that music can improve crop yields. Students are required to follow the key features of project-based learning to plan and execute an inquiry to determine the influence of music on seed germination. Students undertaking a literature study will find research showing that music affects the viscosity of the plasmalemma and the availability of intercellular Ca2+, which, in turn, influences the activity of membrane-based enzymes. This can lead to larger amounts of water, nutrients, and growth regulators entering the plant cell. The article also reflects on data obtained from high school biology students as they engage in the learning activity.
Drift and Directional Selection Are the Evolutionary Forces Driving Gene Expression Divergence in Eye and Brain Tissue ofHeliconiusButterflies
Authors: Catalán Ana , Briscoe Adriana D , Höhna Sebastian
Published: August 2019

Characterization of gene expression patterns across species - and the evolutionary forces driving them - can reveal processes that have remained conserved across species, as well as those that have changed in a species- specific manner...

Investigating gene expression evolution over micro- and macroevolutionary timescales will expand our understanding of the role of gene expression in adaptation and speciation. In this study, we characterized the evolutionary forces acting on gene expression levels in eye and brain tissue of five Heliconius butterflies with divergence times of ∼5–12 MYA. We developed and applied Brownian motion (BM) and Ornstein–Uhlenbeck (OU) models to identify genes whose expression levels are evolving through drift, stabilizing selection, or a lineage-specific shift. We found that 81% of the genes evolve under genetic drift. When testing for branch-specific shifts in gene expression, we detected 368 (16%) shift events. Genes showing a shift toward upregulation have significantly lower gene expression variance than those genes showing a shift leading toward downregulation. We hypothesize that directional selection is acting in shifts causing upregulation, since transcription is costly. We further uncovered through simulations that parameter estimation of OU models is biased when using small phylogenies and only becomes reliable with phylogenies having ≥ 50 taxa. Therefore, we developed a new statistical test based on BM to identify highly conserved genes (i.e., evolving under strong stabilizing selection), which comprised 3% of the orthoclusters. In conclusion, we found that drift is the dominant evolutionary force driving gene expression evolution in eye and brain tissue in Heliconius. Nevertheless, the higher proportion of genes evolving under directional than under stabilizing selection might reflect species-specific selective pressures on vision and the brain that are necessary to fulfill species-specific requirements.
Mixed-Race Marriage -- Hollywood Version
Authors: Toh Hai Leong
Published: August 2019

A VIEW FROM SINGAPORE The very first images I had of black-and-white sexual attraction were those from 100 Rifles (Tom Gries, 1969) where Jim Brown makes passionate love to Raquel Welch and in the slick Shaft (Gordon Parks, 1971) where the tough private detective Richard Roundtree has a fine wet time in the shower with a prostitute. The theme of interracial or mixed-race sex and marriage has been, since D. W. Griffith's time, problematic for Hollywood, the world's greatest Dream Factory. The most prominent film to treat this theme seriously is arguably Stanley Kramer's Guess Who's Coming to Dinner (1967). The question of interracial relationship is more sublimated in this film, where Katherine confesses to her mother (Katharine Hepburn), she and Sidney Poitier have not had sex because "he wouldn't let me!" Though controversial in the tumultuous Civil Rights era, it now looks tame and timid as a social...
African Cinema
Authors: Stoneman Rod
Published: August 2019

AFRICAN CINEMA: ADDRESSEE UNKNOWN Thirty years after Sembene's pioneering Borom Sarret, this is a moment of celebration but also of self-assessment for emergent African cinema -- an opportunity to think through questions of funding, the basis of production, and the way that various African films address their different audiences. Pieces of Identity In Europe and North America a nebulous imaginary unity is projected onto Africa. This lazily assumed misconception continues to underpin the distorting insularity and ignorance of the north. It is precisely an imaginary, implicit unity and not to be confused with the distinct political unity proposed by the project of Pan-Africanism, built from conscious political and cultural alliances. One does not have to be too familiar with the continent to understand that there are also many Africas -- culturally, politically, socially. Indeed more than a thousand languages are spoken in Africa and there are as many...
Reading the Subtitles and Captions in Dances With Wolves
Authors: Tiessen Hildi , Tiessen Paul
Published: August 2019

DANCES WITH WOLVES INVITES THE VIEWER into the inner and outer worlds of Lt. Dunbar, alias Kevin Costner, alias Dances With Wolves. The audio-visual text of this film -- which ends with the "spine-tingling howl" of a wolf framed by a "great, yellow full moon" and, then, Dances With Wolves and Stands With A Fist (played by Mary McDonnell) walking together up a canyon trail, away from the camera which "slowly pulls back" -- precedes the coda-like pronouncement of the closing caption: "Thirteen years later, their homes destroyed, their buffalo gone, the last band of free Sioux submitted to white authority at Fort Robinson, Nebraska. The great horse culture of the plain was gone and the American Frontier was about to pass into history."(1) The epic-length text of Dances With Wolves invites the viewer to identify totally and unabashedly with the almost absurdly heroic and deliciously vulnerable child/man...
The Enduring Legend of Grace Kelly
Authors: Fox Joan
Published: August 2019

FEW FEMALE STARS of the fifties have joined the legendary immortals of the American cinema. There were many beauties then and some great magnetic stars like Doris Day. Yet only the mysterious extrovert, Marilyn Monroe, and the mysterious introvert, Grace Kelly, shone with a brighter light. Like Monroe, Grace Kelly captured the imagination of future generations. There is public and media fascination with Princess Grace and everything that touched her. There have been rumours of a cult adoration in Monaco which has sought to have her enrolled in the first declension toward sainthood. The tabloid rags have it that she did not die but was so badly shattered in her fatal accident that her family had her put away in a secret place. But, because she is a kind soul, she has ventured forth to a hidden rendezvous with Jack Kennedy in his secret place to comfort the brain-damaged...
Hong Kong 1995
Authors: Teh Limin , Toh Hai Leong
Published: August 2019

SINCE 1985 THE HONG KONG INTERNATIONAL FILM FESTIVAL (HKIFF) has been the guardian of Asian cinema. Apart from screening an eclectic range of Asian and international films, it regularly runs comprehensive retrospectives which highlight both prominent and little-known Asian directors in events such as the thematic "Hong Kong Cinema Retrospective." In celebrating the Centenary of Cinema this year, the 19th HKIFF focused its attention on archival motion pictures collectively titled "Early Images of Hong Kong and China." An exhibition of the same theme was held concurrently at the City Hall. Among the most striking of the nearly 126 films from 44 countries exhibited in the Colony's bustling art cinemas were engaging movies that featured peculiar familial clans, haunted loners and bizarre relationships. The intensive 16-day affair (7th to 22nd April) opened with Jiang Wen's rites-of-passage film, In the Heat of the Sun. In his introductory speech, the acclaimed Mainland Chinese...
Dark Alchemy: The Films of Jan Švankmajer
Authors: Uhde Jan
Published: August 2019

The ARCIMBOLDO OF ANIMATION Peter Hames' Dark Alchemy is the first book publication on the Czech master animator Jan Švankmajer. This may sound surprising, since Svankmajer, a pre-eminent Czech artist has produced twenty-six shorts and two features over the last three decades and is the recipient of numerous international festival prizes and awards. Despite the critical acclaim, his achievements have remained in partial obscurity. There may be more than one reason for this peculiarity: most of Švankmajer's artistic career has coincided with the totalitarian rule in the former Czechoslovakia. The Communist regime was not at all interested in encouraging or promoting an artist whose work represented an opposing view to the government's cultural ideology and practice, and was thus barely tolerated by the authorities....
Eye of the World: John L. Baird and Television (part 2)
Authors: Baird Malcolm H. I.
Published: August 2019

IN THE FIRST ARTICLE of this series,(1) Adrian Hills has skilfully brought us through John Logie Baird's early life to the "birth of television," the first public demonstration in 1926. In this part I will write of the years from 1926 until my father's death in 1946, and also comment on how the perceptions of his work have changed since 1946. This article is dedicated to the memory of my mother, Margaret Baird (1907-1996). Early Television AchievementsThe first public demonstration of television, in the cramped London attic room in January 1926, marked a turning point for Baird. One of the scientists at the demonstration was heard to comment "Well, he got it right. It's only a matter of .s.d. to carry on developments." Public interest was immense and the small company that had been formed six months earlier, Television Limited, was able to expand. One of its...
Postwar Korean Cinema
Authors: Toh Hai Leong
Published: August 2019

POSTWAR KOREAN CINEMA: FRACTURED MEMORIES AND IDENTITY IT IS generally agreed by South Korean film scholars that the Golden Flowering of Korean cinema took place in the turbulent 1950s after the end of the 1950-53 Korean War, amidst the rapid industrialisation and modernisation of a predominantly agrarian society based on a highly stratified class system. Like its highly reactive Hongkong counterpart, South Korean cinema acts as a sensitive reflection of the constant changes and upheavals -- both socio-economic and political. These include the liberation in 1945 from Japan, the Korean War, the 1970s economic miracle and the current traumatic transformations that are shaping this troubled peninsula. This year, the astute Asian programmer of the 20th Hongkong International Film Festival, Ms Wong Ain-ling introduced a total of 12 "Rediscovered Korean Classics," with 6 of them set in the 1950s and 60s, emphasising the important role of Korean women during these...
The Cultural Exception: Why?
Authors: Liehm Anthony J.
Published: August 2019

THE NEXT CENTURY will definitely be a century of the audio-visual, an alpha-numeric century. This will have an enormous impact on culture. In every household, of whatever might then be called the developed world, there will be a huge TV screen and a smaller one in each room. Add the internet and other advances technology will offer and you will easily agree that, whether we like it or not, the audio-visual media will play the role of the most important, dominant vectors of art and culture. Furthermore, the attitude towards these developments of still too many intellectuals and artists -- one of hostility and snubbing the audio-visual instead of trying to influence it and occupy an increasingly important position in its structures and programs -- seems a suicidal one. These are the reasons why the Europeans fight for a "cultural exception" to the GATT agreements on free trade concerning...
A History of Narrative Film
Authors: Uhde Jan
Published: August 2019

A CURSORY EXAMINATION of the Third edition of David Cook's film history already reveals an impressive publication. The more then a thousand pages of dense text include 1,500 colour and monochrome illustrations, a glossary with 250 terms, a bibliography of over 2,000 titles on the history and theory of cinema, and an extensive index. This new edition does not fundamentally change Cook's approach used in the earlier editions (1981 and 1990) -- it simply makes the good even better. Examining narrative film medium's history from its inception up to the mid 1990s, Cook has thoroughly updated the entire text, including the bibliography; he has also added several new sections, such as those on ethnic cinema, Scandinavian and New Spanish cinema. Particularly commendable is the inclusion of many inadequately explored or neglected spots on the world film map: Baltic (Lithuania, Latvia, Estonia); Transcaucasian (Georgia, Armenia, Azerbaijan); Central Asian (Uzbekistan, Kazakhstan,...
A Clockwork Orange: The First 25 Years
Authors: Ng Yvonne
Published: August 2019

TWENTY-FIVE YEARS AFTER ITS FIRST RELEASE in New York on 20th December 1971, Stanley Kubrick's A Clockwork Orange, adapted from the 1962 novel by Anthony Burgess, has acquired a prominent place in the history of cinema. However, at the time of its release, it generated much controversy and was heavily criticised in its artistic, political and social dimensions. A New York Times reviewer called it "a marvelously executed, sensationalist, confused and finally corrupt piece of pop trivia, signifying nothing."(1) Next, Fred M. Hechinger, an American liberal, accused the film of promoting fascist ideology.(2) In March 1972, the Detroit News refused to give advertising and publicity space to X-rated films, judging them to be of "pornographic nature" and instituted its policy with A Clockwork Orange.(3) On the other hand, the film was also nominated for four 1971 Academy Awards and it received the 1971 New York Film...
Music as Spiritual Metaphor in the Cinema of Ingmar Bergman
Authors: Bird Michael
Published: August 2019

SECRET ARITHMETIC OF THE SOUL: MUSIC AS SPIRITUAL METAPHOR IN THE CINEMA OF INGMAR BERGMAN Prelude: General Reflections on Music and the Sacred: It frequently happens that in listening to a piece of music we at first do not hear the deep, fundamental tone, the sure stride of the melody, on which everything else is built... It is only after we have accustomed our ear that we find law and order, and as with one magical stroke, a single unified world emerges from the confused welter of sounds. And when this happens, we suddenly realize with delight and amazement that the fundamental tone was also resounding before, that all along the melody had been giving order and unity...        - Rudolf Bultmann(1) I said to myself, it is as if the eternal harmony were conversingwithin itself, as it may have done in...
Short films in Canada
Authors: Thompson Patricia
Published: August 2019

(1) SPEAKING OF MOVIESDirector: Michael Ostroff. Narrator: Laurie Lapierre. Canada 1994, 24 min. Pioneer filmmaker Gordon Sparling speaks out the title -- he was over 90 then and, like much of Canadian film history, long forgotten. This little documentary gives a brief glimpse of Sparling's talents, and whets the appetite for more of the lively and punchy "shorts" he made as head of production at Associated Screen News in Montréal from 1930-1954. These ten-minute theatrical entertainments were shot inexpensively and covered many subjects, with music, drama and humour abounding, and in the 1930's were being produced at the rate of one a month. Among the tiny excerpts in this film, Rhapsody in Two Languages was perhaps the most well-known, but it's fascinating to see "Music from the Stars" presenting a young Horace Lapp and his orchestra. Horace also lived to a ripe old age, and for many...
DAKWAH DAN PEMBERDAYAAN MASYARAKAT
Authors: Masrial Masrial
Published: August 2019

This paper aims to describe the role of transformative da'wah in community empowerment. This is library research type by gathering various references related to da’wah. The results of the analysis shows that for the eradication of crime, that is human stupidity of all forms, in the form of kufr, polytheism, demoralization, poverty and dehumanization carried out by the method of preaching, both in the form of oral, written, and deed. Da'wah must not neglect the fulfillment of human needs as the object of da'wah consisting of material or material, spiritual or psychological dimensions, and social or social aspects.
PENGARUH LOCUS OF CONTROL EKSTERNAL TERHADAP IMPULSIVEBUYING PADA MAHASISWA DENGAN JENIS KELAMIN SEBAGAI VARIABEL MODERATOR
Authors: Agustin Lusi Tania , Sarsono Sarsono
Published: August 2019

This study aims to examine the effect of external locus of control based on students’ gender towards impulsive buying. The subjects of this study are 80 students in the Special Region of Yogyakarta, aged 17-21 years. The Impulsive Buying and External Scales of Locus of Control were the instruments of this research. Simple linear regression analysis used as the data analysis. The results showed that external locus of control had a significant influence on impulsive buying in students, with F count of 56.702 and p = 0.000 (0 <0.010). This showed a significant influence between impulsive buying of clothing products with external locus of control on students. There is a positive influence between external locus of control on impulsive buying and gender as a moderator variable. The hypothesis proposed in this study is acceptable. It is concluded that between impulsive buying and external locus of control occurs because of causality or influence each other.
Female Activism and Leadership through Social Media in Egypt during the Arab Spring
Authors: Al-Barghouthi Samar
Published: August 2019

This article provides a detailed analysis of the blog of an Egyptian female activist, Nawara Negm, during the critical period of the Egyptian Revolution of 2011. The analysis presents the contents of the blog thematically, through identifying strategies and values and in terms of the author’s shifting terminology by undertaking a quantitative and qualitative analysis of Negm’s changing lexicon. The intersection of gender, nationalism, political activism, and Islam make this individual and her blog important examples of new spaces for the female voice in Arab Muslim contexts.
Estratégias de Inbound Marketing em Uma Indústria 3.0
Authors: Almeida Sueli Sales
Published: August 2019

A difusão entre a internet e o marketing permitiu as empresas explorarem novos campos de atuação frente ao mercado, assim o marketing digital surgiu para facilitar o processo de compras e vendas, entre as ferramentas utilizadas por este, está o inbound marketing. O objetivo do presente estudo de caso foi propor uma discussão sobre o uso e aplicação de estratégias de inbound marketing e verificar a aplicação desta nova filosofia de marketing por uma indústria brasileira 3.0 de médio porte. Desta forma, foi realizada uma pesquisa survey, através da plataforma do Google Docs para se obter informações sobre a aplicação do inbound marketing na mesma, bem como as principais ferramentas utilizadas e as que mais fidelizam os clientes. Os resultados do estudo demonstraram que as estratégias do Google Adwords, bem como algumas estratégias de marketing de relacionamento direto são os meios que mais fidelizam seus clientes. Dentre as principais dificuldades encontradas numa indústria 3.0 foram mencionados a preocupação na geração de conteúdo de qualidade, a falta de recursos para as áreas de marketing, bem como para a implementação de estratégias mercadológicas e a compreensão da complexibilidade dos mercados-alvos.
Prova de Conceito e Análise de Desempenho em Protótipo de Sistema para o Tratamento Natural de Efluentes Domésticos
Authors: Narcizo Ramon Baptista , Prucoli Martins Antonisio , Cardoso Rodolfo , Tammela Iara , Siqueira Madeira Henrique
Published: August 2019

Esse artigo apresenta a concepção, o processo de desenvolvimento e os resultados operacionais iniciais do projeto de um sistema energeticamente eficiente e de baixo custo para o tratamento natural de efluentes domésticos. O objetivo do projeto era o de desenvolver um sistema para o tratamento, reuso e a reciclagem da água consumida em um típico domicílio brasileiro, que usa os próprios micro-organismos encontrados nos efluentes no processo, sem demanda de aditivos químicos. O sistema é projetado para funcionar com baixo custo operacional, de manutenção e de consumo energético. Como método, foi empregada uma versão simplificada da proposição de Ulrich e Eppinger (2015) para o desenvolvimento de novos produtos, avançando até a fase de testes e refinamentos. Iniciado em 2015, o projeto atualmente já concluiu as primeiras etapas do desenvolvimento, possuindo um protótipo funcional capaz de tratar cerca de quatro mil litros de efluentes por dia, com resultados promissores comprovados por meio de análises laboratoriais. Como resultados, tanto o desempenho individual de cada módulo, assim como também o desempenho global do sistema, são apresentados e discutidos à luz do planejamento e das especificações iniciais. O artigo é concluído argumentando-se que o sistema é promissor, constituindo-se numa efetiva prova de conceito para o projeto.
Uma Proposta de Melhoria no Arranjo Físico de Uma Fábrica do Setor Têxtil
Authors: Coleone Murilo , Junqueira Martarelli Fróes Nádia
Published: August 2019

Perante ao aumento da competividade, diversas empresas têm investido na melhoria dos seus processos produtivos, visando um aumento da eficiência e efetividade. Uma das formas de obter tais resultados, é realizar melhorias no arranjo físico do chão de fábrica. Dessa forma, este artigo tem como objetivo realizar um estudo de caso em uma empresa no setor têxtil, situada no interior do estado de São Paulo, visando desenvolver uma proposta de melhoria no layout de um setor específico. Para isso, realizou-se o diagnóstico da situação atual, e elaborou-se uma proposta de layout. As melhorias obtidas pelo novo arranjo físico contemplam eliminação de movimentações desnecessárias e diminuição do retrabalho.
Gestão de Micro e Pequenas Empresas: Uma proposta pedagógica para o desenvolvimento de uma disciplina do curso de Engenharia de Produção
Authors: De Almeida Thairone Ezequiel
Published: August 2019

O elemento central deste artigo foi realizar um exame sistemático dos principais itens existentes na literatura para elaborar uma proposta pedagógica no desenvolvimento da disciplina de Gestão de Micro e Pequenas Empresas (GMPE) do curso de Engenharia de Produção. Perante o contexto, buscou-se fazer um estudo exploratório nas diretrizes curriculares do curso e na literatura relacionada à gestão de empresas de pequeno porte. Como resultado, ressalta-se a construção de um quadro sinóptico para sistematizar o Plano de Trabalho Docente (PTD) e justificar a sua proposta pedagógica, metodologias, materiais textuais, recursos tecnológicos e processos de avaliação a serem utilizados nas aulas da disciplina. Dessa forma, espera-se que este estudo seja relevante do ponto de vista acadêmico, pois abrange a estruturação de um PTD da disciplina de GMPE para o curso de Engenharia de Produção, podendo ser adaptado para outras composições curriculares. As conclusões provenientes da pesquisa destacam o quanto é importante o planejamento educacional no ensino superior, bem como a relevância da abordagem de particularidades das micro e pequenas empresas no processo de ensino-aprendizagem do engenheiro de produção.
Fatores Críticos de Adoção da Tecnologia da Informação (TI) em Saúde e o seu Impacto na Gestão: um estudo exploratório
Authors: Gonçalves Marina , De Mattos Claudia Aparecida , Chang Junior João
Published: August 2019

O progresso em tecnologias da informação em saúde oferece novas oportunidades, bem como novos cenários de aplicação, trazendo benefícios em qualidade dos serviços médicos e redução dos custos de saúde. Porém, a literatura científica relacionada com este tema parece ser ainda muito dispersa e fragmentada, demandando novos estudos. Assim, o objetivo geral deste trabalho é investigar a decisão de adoção de tecnologias informação em saúde, e desenvolver uma lista indicando os fatores críticos que influenciam sua adoção e o impactos na gestão da saúde. Para o desenvolvimento da pesquisa foi adotada a pesquisa Qualitativa através de um estudo de caso em um Organização de Saúde e a Tecnologia analisada foi a implantação do Prontuário Eletrônico. Com relação aos resultados, foram identificados os seguintes fatores críticos de adoção: elaboração de um plano diretor de TI, integração com os sistemas legados, tendências tecnológicas promovendo inovação, envolvimento da alta administração, gestão de projetos com equipes hibridas, plano de capacitação para equipe enfermagem, pressão da concorrência, perfil dos pacientes e a necessidade de novos modelos de negócio. Os principais impactos observados com a adoção dos sistemas foram: melhoria da segurança do paciente, redução do Índices de erro de medicamento, visibilidade das informações.
Impacto da Manufatura Aditiva nos Processos Tradicionais de Produção: Um Estudo de Caso em Joalheria Artesanal
Authors: Mourão Laura Braz , De Miranda Carlos Alberto Silva , Tavares Paulo Henrique Campos Prado
Published: August 2019

Atualmente, com as novas formas de produzir, em que as organizações buscam gastar menos e produzir mais as tecnologias ganham espaço para apoiar essas novas formas de produção. O uso da impressão 3D vem quebrando paradigmas e criando valor para os clientes de uma forma a transformar as maneiras tradicionais de produção. No setor joalheiro essa tecnologia já vem sendo utilizada como ferramenta de construção de modelos, um trabalho anteriormente realizado manualmente por um modelador. Nesse artigo os processos de fabricação de joias tradicionais serão apresentados e também será abordada a utilização da tecnologia de prototipagem por impressão 3d no setor joalheiro. Além de um estudo de caso comparando a fabricação de uma joia pelo modo tradicional e com o uso da manufatura aditiva. Foi comparado o processo de desenvolvimento de um projeto de uma joia, através do processo de manufatura artesanal tradicional, onde o desenho do artesão foi modelado em software CAD e submetido a uma plataforma online de serviços de impressão em ouro, para efeitos de comparação. Evidenciamos o potencial de aplicação desta tecnologia emergente e a possibilidade da otimização e redução de custos. Em contraposição, também realçamos a importância fundamental da produção artesanal e o valor atribuído a esta atividade neste setor produtivo específico.
Análise de vibração em derriçadora de café portátil
Authors: Solane Rafael Brito , Boaventura Alana Indah , Cazani Ana Carolina , Guarnetti João Eduardo dos Santos
Published: August 2019

A vibração é uma das variáveis mais importantes a serem entendidas e interpretadas no projeto e melhoria de máquinas. As derriçadoras portáteis têm se mostrado de suma importância na colheita do café para o pequeno e médio produtor. A vibração inerente do funcionamento das ferramentas elétricas manuais se propaga pelas mãos e braços do operador, gerando preocupações quanto a saúde ocupacional dos trabalhadores expostos a essa variável ergonômica. O presente estudo teve como objetivo avaliar os níveis de vibração transmitidos por derriçadoras de café manual, baseando-se no comportamento (aceleração) da empunhadura em função de cada tipo de ponteira utilizada juntamente com a variação das rotações de trabalho. Os dados experimentais obtidos foram analisados através do software g4 e manipulados estatisticamente via planilha eletrônica e confrontados com a norma vigente. Os resultados mostraram que os níveis de aceleração na condição de alta rotação, extrapolam o que é permitido pela norma para uma jornada de 8 horas de trabalho, no entanto na condição de baixa rotação os níveis de vibração do equipamento atende o que é preconizado pelas normas.
A importância da comunicação no sucesso de gerenciamento de projetos
Authors: Muranaka Renata Sayuri , Facin Ana Lucia Figueiredo , Pacheco do Vale João Walter Saunders , De Carvalho Marly Monteiro
Published: August 2019

A comunicação é um fator essencial em todas as fases do gerenciamento de projetos, conectando todas as partes interessadas. É através da comunicação eficiente que os objetivos dos projetos podem ser cumpridos e o sucesso dos mesmos pode ser atingido. O trabalho teve como objetivo principal avaliar a importância da comunicação no sucesso do gerenciamento de projetos. Também foram caraterizados os canais de comunicação mais utilizados, os itens que melhoram e que prejudicam a comunicação, e a satisfação com o processo de comunicação. Para tanto, o método de pesquisa através do questionário survey foi aplicado às pessoas que possuem experiência em gestão de projetos. As principais informações obtidas foram que as reuniões formais são os canais de comunicação mais utilizados pelos participantes e são também considerados os mais eficientes. Também foi levantado que papéis e responsabilidades bem definidos são os itens que melhoram a comunicação e que a centralização de informações é a maior barreira à mesma. A maior insatisfação dos participantes é com as habilidades de comunicação dos gerentes de projetos e a maior satisfação é com a comunicação entre todos os membros da equipe. A grande maioria dos participantes reconheceu a importância da comunicação, considerando-a essencial para o sucesso no gerenciamento de projetos.
Coreset Stochastic Variance-Reduced Gradient with Application to Optimal Margin Distribution Machine
Authors: Tan Zhi-Hao , Zhang Teng , Wang Wei
Published: August 2019

A major problem for kernel-based predictors is the prohibitive computational complexity, which limits their application in large-scale datasets. Coreset, an approximation method which tries to cover the given examples with a small set of points, can be used to remain the prominent information and accelerate the kernel method. In this paper, we provide perhaps the first coreset-based kernel-accelerating optimization method that has a linear convergence rate, which is much faster than existing approaches. Our method can be used to train kernel SVM-style problems and obtain sparse solutions efficiently. Specifically, the method uses SVRG as the framework, and utilizes the core points to approximate the gradients, so it can significantly reduce the complexity of the kernel method. Furthermore, we apply the method to train ODM, a kernel machine enjoying better statistical property than SVM, so that we can reduce the risk of compromising the performance while encouraging the sparsity. We conduct extensive experiments on several large-scale datasets and the results verify that our method outperforms the state-of-the-art coreset approximation method in both efficiency and generalization, while simultaneously achieving significant speed-up compared to non-approximation baselines.
Optimization of Hierarchical Regression Model with Application to Optimizing Multi-Response Regression K-ary Trees
Authors: Tavallali Pooya , Tavallali Peyman , Singhal Mukesh
Published: August 2019

THIS PAPER HAS BEEN RETRACTED
The University of California, Merced campus, recently completed a formal investigation into allegations that content in this paper ("Optimization of Hierarchical Regression Model with Application to Optimizing Multi-Response Regression K-ary Trees," in Proceedings of the AAAI Conference on Artificial Intelligence, 2019, vol. 33, pp. 5133– 5142) was not properly attributed to the novel work of Professor Carreira—Perpiñán, reflected in a previously published paper, "Alternating Optimization of Decision Trees, with Application to Learning Sparse Oblique Trees,” published in Advances in Neural Information Processing Systems, 2018, (vol. 31, pp. 1211–1221). The UC Merced investigation was conducted in consultation with NSF, which funded the research reflected in the original Advances in Neural Information Processing Systems paper, and in accordance with UC Merced policies and procedures on research misconduct. The allegations were substantiated by a preponderance of the evidence. The investigation committee found, in pertinent part, that “key novel ideas in the AAAI paper were taken from the NeurIPS paper without appropriate credit." The initial submission of the AAAI paper, upon which the acceptance decision was made, did not include a reference to the NeurIPS paper, and thus represented a clear case of plagiarism. A citation to the NeurIPS paper was added in the final revision, after the reviewers had already decided to accept it, making it impossible for the AAAI peer-review process to consider the contributions of the AAAI article in light of the earlier work reported in the NeurIPS paper. Furthermore, the citation to the NeurIPS paper in this manuscript does not properly credit the original contributions of the NeurIPS paper and how those ideas were reflected in the work reported in this paper. In response to a formal request made by the University of California's Chancellor's office, and after careful review by the AAAI Publications Committee, AAAI has decided to retract this paper. One of the conditions of submission of a paper for publication in AAAI conference proceedings is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere. Reuse of any data should be appropriately cited. As such this paper represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of this proceedings that this was not detected during the submission process.
Clipped Matrix Completion: A Remedy for Ceiling Effects
Authors: Teshima Takeshi , Xu Miao , Sato Issei , Sugiyama Masashi
Published: August 2019

We consider the problem of recovering a low-rank matrix from its clipped observations. Clipping is conceivable in many scientific areas that obstructs statistical analyses. On the other hand, matrix completion (MC) methods can recover a low-rank matrix from various information deficits by using the principle of low-rank completion. However, the current theoretical guarantees for low-rank MC do not apply to clipped matrices, as the deficit depends on the underlying values. Therefore, the feasibility of clipped matrix completion (CMC) is not trivial. In this paper, we first provide a theoretical guarantee for the exact recovery of CMC by using a trace-norm minimization algorithm. Furthermore, we propose practical CMC algorithms by extending ordinary MC methods. Our extension is to use the squared hinge loss in place of the squared loss for reducing the penalty of overestimation on clipped entries. We also propose a novel regularization term tailored for CMC. It is a combination of two trace-norm terms, and we theoretically bound the recovery error under the regularization. We demonstrate the effectiveness of the proposed methods through experiments using both synthetic and benchmark data for recommendation systems.
HyperAdam: A Learnable Task-Adaptive Adam for Network Training
Authors: Wang Shipeng , Sun Jian , Xu Zongben
Published: August 2019

Deep neural networks are traditionally trained using humandesigned stochastic optimization algorithms, such as SGD and Adam. Recently, the approach of learning to optimize network parameters has emerged as a promising research topic. However, these learned black-box optimizers sometimes do not fully utilize the experience in human-designed optimizers, therefore have limitation in generalization ability. In this paper, a new optimizer, dubbed as HyperAdam, is proposed that combines the idea of “learning to optimize” and traditional Adam optimizer. Given a network for training, its parameter update in each iteration generated by HyperAdam is an adaptive combination of multiple updates generated by Adam with varying decay rates . The combination weights and decay rates in HyperAdam are adaptively learned depending on the task. HyperAdam is modeled as a recurrent neural network with AdamCell, WeightCell and StateCell. It is justified to be state-of-the-art for various network training, such as multilayer perceptron, CNN and LSTM.
CECL and the Credit Cycle
Authors: Loudis Bert , Ranish Ben
Published: August 2019

We find that that the Current Expected Credit Loss (CECL) standard would slightly dampen fluctuations in bank lending over the economic cycle. In particular, if the CECL standard had always been in place, we estimate that lending would have grown more slowly leading up to the financial crisis and more rapidly afterwards. We arrive at this conclusion by estimating historical allowances under CECL and modeling how the impact on accounting variables would have affected banks&#x27; lending and capital distributions. We consider a variety of approaches to address uncertainty regarding the management of bank capital and predictability of credit losses.
Measure 40 worm feeding with bioluminescent bacteria after drug treatment v1
Authors: Ding Serena
Published: August 2019

Protocol uses bioluminescently labelled bacteria (Gregor et al, 2008, Addgene Plasmid #107879, https://www.pnas.org/content/115/5/962) to measure population feeding of 40 adult C. elegans worms following serotonin or naloxone drug treatment.
Compare estimates of people living 1, 5 and 10km from the coast in Pacific Island Countries and Territories v1
Authors: Bright Phil , L. Andrew Neil , de la Rua Luis , Jiau Teoh Shwu , Vickers Mathew
Published: August 2019

Compare estimates of the numbers of people living within 1, 5, and 10 km from the coast in Pacific Island Countries and Territories (PICTs). These distances are somewhat arbitrary, but in the absence of generally agreed definitions of the ‘coastal zone’ and of more integrated analyses that include elevation above sea level, livelihood portfolios and other measure of exposure to the ocean, they provide a logical basis for the analyses. Three coastal zones at 1, 5, and 10 km were mapped onto every populated island for each PICT. People residing within 1 km were considered to live on the coast, those within 5 km included those who could still easily walk to the coast and 10 km, those who interact with coastal communities (e.g. in terms of access to markets or other activities) and who would be able to easily get to the coast with some form of transport. The two global datasets used to spatially distribute populations were the SEDAC-CIESIN Gridded Population of the World v4 and the Oak Ridge National Laboratory LandScan™. GPWv4 is a minimally modelled population dataset that uniformly distributes census data from their native enumeration areas. LandScan™ allocates population census data using dasymetric cartographic techniques relying on ancillary data such as land cover, roads, terrain slope, urban extent, and accessibility to model population density at 30 arc-second grid resolution within administrative boundaries. Both global datasets distributed populations within enumeration areas to 30 arc second cells (approximate 1 km2 at the Equator). The following protocol explains the workflow used to calculate the Coastal Population Estimates for PICTs. The protocol involves three main steps: Generation of 1, 5 and 10 km coastal buffers Spatial disaggregation of the census population datasets using one of the three methods based on data availability. This step is not applicable for the global population grids. Overlay the coastal buffer mask on the disaggregated population datasets and sum the population contained within the coastal buffers to calculate the percentage of the country’s population within each of the three coastal zones.
Metadata extraction Zeiss CZI, before conversion to JPEG/TIFF (MacOS) v1
Authors: John Scott
Published: August 2019

Extract metadata from Zeiss CZI files before conversion to TIFF/JPEG, using macOS. Require "Fiji" and legacy Java 6 runtime for macOS 10.13
Make serotonin and naloxone drug plates v1
Authors: Ding Serena
Published: August 2019

Protocol for making a set of three serotonin drug plates and a set of three naloxone drug plates. Serotonin (20 mM) is added to molten agar, whereas naloxone (10 mM) is made into a 10X stock solution in water first before being spread over agar plates to achieve the final concentration. Each 35 mm drug plate contains 3 mL low peptone NGM agar and the drug, and is always made up fresh the day before imaging experiments. For naloxone methods, refer to https://www.ncbi.nlm.nih.gov/pubmed/25898004.
Linguistic Landscape of Religious Signboards in Ado Ekiti, Nigeria: Culture, Identity and Globalisation
Authors: Inya Blessing T.
Published: August 2019

This paper focuses on the linguistic landscape (LL) of religious signboards in select areas of Ado Ekiti, Nigeria with a view of establishing the relationship between the languages used on these signboards and the implication for identity, globalisation and culture. Fifty-three LL items were photographed for the study. The areas selected were based on activity level and the number of religious signboards they featured. The data were analysed both quantitatively and qualitatively. The findings revealed the dominance and the pervasiveness of the English language over and across the other languages in the public space. The use of Yoruba texts across the items revealed religio-cultural and loyalist reasons while the use of Arabic confirmed the inherent attachment of the language to Islamic religion, and fostered a religion-based collective identity between the sign writer and the sign reader.
Visualization Analysis of Research of English for Specific Purposes in China Based on CiteSpace (2000-2017)
Authors: Hu Fanghui
Published: August 2019

Based on the data from CNKI database, this study used CiteSpace to analyze the research hotspots and development trends of studies on English for Specific Purposes in China from 2000 to 2017. The results show that research hotspots mainly include college English ESP teaching reform, ESP teaching methods and models, needs analysis and ESP, ESP curriculum provision and curriculum design. The domestic studies on ESP experienced slow development in controversy, rapid development in practice and deep development with modern educational technology. Domestic ESP research has yielded fruitful results, but in the future, research on ESP evaluation system, ESP teachers, ESP corpora development, and ESP textbook construction should be deeply explored.
A Comparative Study of the Miserable Fate of Tess and Xianglin’s Wife from Legal System
Authors: Chen Haiting , Lu Jingjing
Published: August 2019

Law and Interdisciplinary research (“Law-and”) has flourished since the 1960s. “Law and literature” is an academic movement under such a background in the United States. The author uses Tomas Hardy's Tess of the d'Urbervilles and Lu Xun's The New-Year Sacrifice to analyze and compare the legal system in British Victorian and Chinese semi-feudal and semi-colonial society, and explores the root causes of the tragic fate of Tess and Xianglin’s Wife. Meanwhile, the paper reveals the predicament of women in the East and West around the 20th century.