bluuebunny/crossref_metadata_2025 huggingface dataset:
A Listeria monocytogenes-Based Vaccine Formulation Reduces Vertical Transmission and Leads to Enhanced Pup Survival in a Pregnant Neosporosis Mouse Model
Authors: Imhof Dennis , Pownall William Robert , Monney Camille , Oevermann Anna , Hemphill Andrew
Published: December 2021

The apicomplexan parasite Neospora caninum is the worldwide leading cause of abortion and stillbirth in cattle. An attenuated mutant Listeria monocytogenes strain (Lm3Dx) was engineered by deleting the virulence genes actA, inlA, and inlB in order to avoid systemic infection and to target the vector to antigen-presenting cells (APCs). Insertion of sag1, coding for the major surface protein NcSAG1 of N. caninum, yielded the vaccine strain Lm3Dx_NcSAG1. The efficacy of Lm3Dx_NcSAG1 was assessed by inoculating 1 × 105, 1 × 106, or 1 × 107 CFU of Lm3Dx_NcSAG1 into female BALB/c mice by intramuscular injection three times at two-week intervals, and subsequent challenge with 1 × 105N. caninum tachyzoites of the highly virulent NcSpain-7 strain on day 7 of pregnancy. Dose-dependent protective effects were seen, with a postnatal offspring survival rate of 67% in the group treated with 1 × 107 CFU of Lm3Dx_NcSAG1 compared to 5% survival in the non-vaccinated control group. At euthanasia (25 days post-partum), IgG antibody titers were significantly decreased in the groups receiving the two higher doses and cytokines recall responses in splenocyte culture supernatants (IFN-γ, IL-4, and IL-10) were increased in the vaccinated groups. Thus, Lm3Dx_NcSAG1 induces immune-protective effects associated with a balanced Th1/Th2 response in a pregnant neosporosis mouse model and should be further assessed in ruminant models.
A Review of UK-Registered and Candidate Vaccines for Bovine Respiratory Disease
Authors: Lemon Joanne L. , McMenamy Michael J.
Published: December 2021

Vaccination is widely regarded as a cornerstone in animal or herd health and infectious disease management. Nineteen vaccines against the major pathogens implicated in bovine respiratory disease are registered for use in the UK by the Veterinary Medicines Directorate (VMD). However, despite annual prophylactic vaccination, bovine respiratory disease is still conservatively estimated to cost the UK economy approximately £80 million per annum. This review examines the vaccine types available, discusses the surrounding literature and scientific rationale of the limitations and assesses the potential of novel vaccine technologies.
Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
Authors: Ramatillah Diana Laila , Gan Siew Hua , Sulaiman Syed Azhar Syed , Puja Dama , Abubakar Usman , Jaber Ammar Ali Saleh , Lukas Stefanus , Jusnita Nina
Published: December 2021

Pneumonia is one of the common complications of SARS-CoV-2 infection where most patients have moderate to severe symptoms that pose a higher risk for death. This study aims to evaluate the treatment outcome of COVID-19-associated Pneumonia among patients with/without comorbidity in a public hospital in Indonesia. This is a retrospective cohort study involving unvaccinated confirmed COVID-19 patients admitted to the hospital between March and December 2020. All confirmed COVID-19 patients with Pneumonia (n = 1522) treated at the hospital were included. The majority of patients (99%) had mild COVID-19 symptoms while the remaining had moderate symptoms. The median age was about 32 years old and the average treatment duration was 6.25 ± 1.83 days. Most patients (88.8%) received a combination of azithromycin and oseltamivir. There was a very significant relationship (p < 0.001) between comorbidities with treatment and duration of treatment of Pneumonia in COVID-19 patients. Although most patients had Pneumonia and comorbidities, they were successfully treated with azithromycin and oseltamivir combination following approximately five days of treatment.
Human Papillomavirus Vaccine Efficacy and Effectiveness against Cancer
Authors: Kamolratanakul Supitcha , Pitisuttithum Punnee
Published: December 2021

Human papillomavirus (HPV) is the most common sexually transmitted infection, with 15 HPV types related to cervical, anal, oropharyngeal, penile, vulvar, and vaginal cancers. However, cervical cancer remains one of the most common cancers in women, especially in developing countries. Three HPV vaccines have been licensed: bivalent (Cervarix, GSK, Rixensart, Belgium), quadrivalent (Merck, Sharp & Dome (Merck & Co, Whitehouse Station, NJ, USA)), and nonavalent (Merck, Sharp & Dome (Merck & Co, Whitehouse Station, NJ, USA)). The current HPV vaccine recommendations apply to 9 years old and above through the age of 26 years and adults aged 27–45 years who might be at risk of new HPV infection and benefit from vaccination. The primary target population for HPV vaccination recommended by the WHO is girls aged 9–14 years, prior to their becoming sexually active, to undergo a two-dose schedule and girls ≥ 15 years of age, to undergo a three-dose schedule. Safety data for HPV vaccines have indicated that they are safe. The most common adverse side-effect was local symptoms. HPV vaccines are highly immunogenic. The efficacy and effectiveness of vaccines has been remarkably high among young women who were HPV seronegative before vaccination. Vaccine efficacy was lower among women regardless of HPV DNA when vaccinated and among adult women. Comparisons of the efficacy of bivalent, quadrivalent, and nonavalent vaccines against HPV 16/18 showed that they are similar. However, the nonavalent vaccine can provide additional protection against HPV 31/33/45/52/58. In a real-world setting, the notable decrease of HPV 6/11/16/18 among vaccinated women compared with unvaccinated women shows the vaccine to be highly effective. Moreover, the direct effect of the nonavalent vaccine with the cross-protection of bivalent and quadrivalent vaccines results in the reduction of HPV 6/11/16/18/31/33/45/52/58. HPV vaccination has been shown to provide herd protection as well. Two-dose HPV vaccine schedules showed no difference in seroconversion from three-dose schedules. However, the use of a single-dose HPV vaccination schedule remains controversial. For males, the quadrivalent HPV vaccine possibly reduces the incidence of external genital lesions and persistent infection with HPV 6/11/16/18. Evidence regarding the efficacy and risk of HPV vaccination and HIV infection remains limited. HPV vaccination has been shown to be highly effective against oral HPV type 16/18 infection, with a significant percentage of participants developing IgG antibodies in the oral fluid post vaccination. However, the vaccines’ effectiveness in reducing the incidence of and mortality rates from HPV-related head and neck cancers should be observed in the long term. In anal infections and anal intraepithelial neoplasia, the vaccines demonstrate high efficacy. While HPV vaccines are very effective, screening for related cancers, as per guidelines, is still recommended.
Locomotor Behavior Analysis in Spinal Cord Injured Macaca radiata after Predegenerated Peripheral Nerve Grafting—A Preliminary Evidence
Authors: Paramasivam Anand , Mickymaray Suresh , Jayakumar Saikarthik , Jeraud Mathew , Perumal Periasamy , Alassaf Abdullah , Aljabr Abdullah Abdulrahman , Dasarathy Sridevi , Rangasamy Suresh Babu
Published: December 2021

Introduction: Primate animal models are being utilized to explore novel therapies for spinal cord injuries. This study aimed to evaluate the efficiency of the transplantation of predegenerated nerve segments in unilateral spinal cord-hemisected bonnet monkeys’ (Macaca radiata) locomotor functions using the complex runways. Materials and Methods: The bonnet monkeys were initially trained to walk in a bipedal motion on grid and staircase runways. In one group of trained monkeys, surgical hemisection was made in the spinal cord at the T12-L1 level. In the other group, hemisection was induced in the spinal cord, and the ulnar nerve was also transected at the same time (transplant group). After one week, the hemisected cavity was reopened and implanted with predegenerated ulnar nerve segments obtained from the same animal of the transplant group. Results: All the operated monkeys showed significant deficits in locomotion on runways at the early postoperative period. The walking ability of operated monkeys was found to be gradually improved, and they recovered nearer to preoperative level at the fourth postoperative month, and there were no marked differences. Conclusion: The results demonstrate that there were no significant improvements in the locomotion of monkeys on runways after the delayed grafting of nerve segments until one year later. The failure of the predegenerated nerve graft as a possible therapeutic strategy to improve the locomotion of monkeys may be due to a number of factors set in motion by trauma, which could possibly prevent the qualities of regeneration. The exact reason for this ineffectiveness of predegenerated nerve segments and their underlying mechanism is not known.
Genotyping of African Swine Fever Virus (ASFV) Isolates in Romania with the First Report of Genotype II in Symptomatic Pigs
Authors: Ungur Andrei , Cazan Cristina Daniela , Panait Luciana Cătălina , Taulescu Marian , Balmoș Oana Maria , Mihaiu Marian , Bărbuceanu Florica , Mihalca Andrei Daniel , Cătoi Cornel
Published: December 2021

The World Organisation for Animal Health has listed African swine fever as the most important deadly disease in domestic swine around the world. The virus was recently brought from South-East Africa to Georgia in 2007, and it has since expanded to Russia, Eastern Europe, China, and Southeast Asia, having a devastating impact on the global swine industry and economy. In this study, we report for the first time the molecular characterization of nine African swine fever virus (ASFV) isolates obtained from domestic pigs in Mureş County, Romania. All nine Romanian samples clustered within p72 genotype II and showed 100% identity with all compared isolates from Georgia, Armenia, Russia, Azerbaijan, Ukraine, Belarus, Lithuania, and Poland. This is the first report of ASFV genotype II in the country.
Sustentabilidade socioambiental para o ensino básico brasileiro: proposta para “o novo normal”
Authors: Pedrini Alexandre Gusmão
Published: December 2021

A pandemia do novo coronavírus (SARS-CoV-2) contaminou mais de 22 milhões de pessoas na Terra e estima-se que, em 2021, mais de seis centenas de milhares de cidadãos venham a óbito no Brasil. A convivência com as variantes do vírus deverá ocorrer, pelo menos, até 2022, cabendo aos três níveis de governo agirem em conjunto no seu enfrentamento. O “Novo Normal “exige um ambiente renovado e demanda a adoção da sustentabilidade socioambiental nas unidades escolares do ensino básico brasileiro. O modelo do Programa Nacional de Escolas Sustentáveis associado ao Programa Dinheiro Direto na Escola e a Agenda Ambiental Federal devem ser devidamente ressignificados e operacionalizados como políticas públicas integradas e transversais no país.
Estructuras pseudo-comparativas en el latín de Tácito
Authors: Gutiérrez Daniel
Published: December 2021

El presente trabajo aborda la problemática cuestión de las estructuras pseudo-comparativas en la lengua latina de la etapa imperial temprana. Problemática que supone, por un lado, la caracterización sintáctica, semántica y pragmática de las mencionadas estructuras, y por otro, el análisis centrado en una porción de esa sincronía. A estos fines se ha seleccionado algunas de las obras que constituyen el corpus del historiador y pensador P. Cornelio Tácito. El trabajo parte de las recientes investigaciones y resultados alcanzados por Manfredini (2015).
El centro de la tierra (Lectura e infancia), de Jorge Monteleone, Buenos Aires, Editorial Ampersand, 2018.
Authors: Lespada Gustavo
Published: December 2021

Reseña del libro en cuestión.
High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy
Authors: Rostami Soheila , Tafvizi Farzaneh , Kheiri Manjili Hamid Reza
Published: December 2021

Introduction: Due to the side effects of drugs, the development of nanoscale drug delivery systems has led to a significant improvement in medicinal therapies due to drug pharmacokinetics changes, decreased toxicity, and increased half-life of the drug. This study aimed to synthesize tamoxifen (TMX)-loaded L-lysine coated magnetic iron oxide nanoparticles as a nano-carrier to investigate its cytotoxic effects and anti-cancer properties against MCF-7 cancer cells. Methods: Magnetic Fe3O4 nanoparticles were synthesized and coated with L-lysine (F-Lys NPs). Then, TMX was loaded onto these NPs. The characteristics of synthesized nanoparticles (F-Lys-TMX NPs) were evaluated by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), dynamic light scattering (DLS), differential scanning calorimetry (DSC), vibrating sample magnetometer (VSM), and thermogravimetric analysis (TGA). The drug release was analyzed at pH 5.8 and pH 7.4. The MCF-7 cells were exposed to F-Lys-TMX NPs, F-Lys NPs, and TMX for 24, 48, and 72 hours. To evaluate the cytotoxic potential of designed nanoparticles, MTT and apoptosis assays, real-time PCR, and cell cycle analysis was carried out. Results: The F-Lys-TMX NPs had spherical morphology with a size ranging from 9 to 30 nm. By increasing the nanoparticles concentration and treatment time, more cell proliferation inhibition and apoptosis induction were observed in F-Lys-TMX NPs-treated cells compared to the TMX. The expression levels of ERBB2, cyclin D1, and cyclin E genes were down-regulated and expression levels of the caspase-3 and caspase-9 genes were up-regulated. Studies on the drug release revealed a slow and controlled pH-dependent release of the nanoparticles. Cell cycle analysis indicated that F-Lys-TMX NPs could arrest the cells at the G0/G1 phase. Conclusion: The findings suggest that F-Lys-TMX NPs are more effective and have the potential for cell proliferation inhibition and apoptosis induction compared to the TMX. Hence, F-Lys-TMX NPs can be considered as an anti-cancer agent against MCF-7 breast cancer cells.
Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers
Authors: Khonsari Fatemeh , Heydari Mostafa , Dinarvand Rassoul , Sharifzadeh Mohammad , Atyabi Fatemeh
Published: December 2021

Introduction: Recent studies showed that rapamycin, as a mammalian target of rapamycin (mTOR) inhibitor, could have beneficial therapeutic effects for the central nervous system (CNS) related diseases. However, the immunosuppressive effect of rapamycin as an adverse effect, the low water solubility, and the rapid in vivo degradation along with the blood-brain barrier-related challenges restricted the clinical use of this drug for brain diseases. To overcome these drawbacks, a transferrin (Tf) decorated nanostructured lipid carrier (NLC) containing rapamycin was designed and developed. Methods: Rapamycin-loaded cationic and bare NLCs were prepared using solvent diffusion and sonication method and well characterized. The optimum cationic NLCs were physically decorated with Tf. For in vitro study, the MTT assay and intracellular uptake of nanoparticles on U-87 MG glioblastoma cells were assessed. The animal biodistribution of nanoparticles was evaluated by fluorescent optical imaging. Finally, the in vivo effect of NLCs on the immune system was also studied. Results: Spherical NLCs with small particle sizes ranging from 120 to 150 nm and high entrapment efficiency of more than 90%, showed ≥80% cell viability. More importantly, Tf-decorated NLCs in comparison with bare NLCs, showed a significantly higher cellular uptake (97% vs 60%) after 2 hours incubation and further an appropriate brain accumulation with lower uptake in untargeted tissue in mice. Surprisingly, rapamycin-loaded NLCs exhibited no immunosuppressive effect. Conclusion: Our findings proposed that the designed Tf-decorated NLCs could be considered as a safe and efficient carrier for targeted brain delivery of rapamycin which may have an important value in the clinic for the treatment of neurological disorders.
Fabrication, characterization, and optimization of a novel copper-incorporated chitosan/gelatin-based scaffold for bone tissue engineering applications
Authors: Bozorgi Azam , Mozafari Masoud , Khazaei Mozafar , Soleimani Mansooreh , Jamalpoor Zahra
Published: December 2021

Introduction: Fabricating composite scaffolds with improved physicochemical properties as artificial microenvironments are of great interest in bone tissue engineering. Given advantageous properties of nano-hydroxyapatite/chitosan/gelatin (nHA/Cs/Gel) scaffolds, the present study aimed to synthesize a modified nHA/Cs/Gel biomimetic scaffold with improved features. Methods: Pure and copper (Cu)-substituted nHA was synthesized using the chemical precipitation method under controlled pH and temperature. Pure and Cu-substituted nHA/Cs/Gel scaffolds were fabricated by salt-leaching/freeze-drying method. Physicochemical characteristics of nanoparticles and scaffolds were explored using XRD, FTIR, FE-SEM/EDX, and ICP. Besides, scaffold mechanical strength, degradation, porosity, swelling, biomineralization, and cytocompatibility were assessed. Results: Pure and Cu-substituted nHA were synthesized and characterized with appropriate Cu substitution and improved physical properties. All scaffolds were highly porous (porosity >98%) and Cu incorporation reduced porosity from 99.555 ± 0.394% to 98.69 ± 0.80% while enlarged the pore size to more than100 µm. Cu-substitution improved the scaffold mechanical strength and the best result was observed in nHA.Cu5%/Cs/Gel scaffolds by the compressive strength 88.869 ± 19.574 MPa. Furthermore, 3% and 5% Cu-substituted nHA enhanced the scaffold structural stability and supported osteoblast spread, adhesion, survival, mineralization, and proliferation. Moreover, long-term and sustainable Cu release from scaffolds was observed within 28 days. Conclusion: Cu-substituted nHA/Cs/Gel scaffolds mimic the porous structure and mechanical strength of cancellous bone, along with prolonged degradation and Cu release, osteoblast attachment, viability, calcium deposition, and proliferation. Taken together, our results indicate the upgraded properties of nHA.Cu5%/Cs/Gel scaffolds for future applications in bone tissue engineering.
Effect of Ti: Sapphire and Nd: YAG Lasers on Shear Bond Strength at the Zirconia - Veneering Ceramic Juncture
Authors: Abraham Anamika , Jain Deshraj , Gupta Alka , Chakera J A
Published: December 2021

Introduction: This study was conducted to assess the impact of nanosecond and femtosecond lasers on shear bond strength at the zirconia - veneering ceramic juncture. Materials and Methods: The first 60 samples of partially sintered zirconia cylindrical discs measuring 7 mm diameter and 4 mm height were milled and sintered. Then they were randomly divided into three groups namely group C (control, n=10), group N (Nd: YAG laser, n=10), and group T (Ti: sapphire laser n=40) which was further divided based on the duration of laser irradiation, into 4 subgroups (n=10 each) which were 30 seconds, 1 minute, 2 minutes and 3 minutes. Surface treatment was done on sintered zirconia discs based on the group. Following the treatment, the discs were ultrasonically cleaned followed by liner application (IPS Emax Zirliner, Ivoclar-Vivadent) and veneer ceramic layering (IPS e.max Ceram, Ivoclar-Vivadent) of 1.5 mm height. Each sample underwent shear stress in the universal test machine on the mounting jig, and bond strength was evaluated. Data were assessed using ANOVA followed by Tukey’s post hoc multiple comparison analyses. Results: According to one-way ANOVA, there was a significant difference in shear bond strength between the groups. Tukey’s post hoc pair wise comparison test showed a significant difference (P value=0.001) in shear bond strength of all pairs except group C and group N. The results of repeated measures, ANOVA (related and dependent groups) and Tukey’s multiple pair wise comparison test showed that there was a significant difference (P value=0.001) in shear bond strength at 30 seconds and all other groups. Conclusion: Ti: sapphire laser irradiation for 30 seconds can be used as potential surface treatment to increase shear bond strength at the zirconia-veneering ceramic juncture.
Clinical Effect of Non-Thermal CO2 Laser Therapy (NTCLT) on Pain Relief of Oral Aphthous Ulcers of Behçet’s Disease
Authors: Zand Nasrin , Ataie-Fashtami Leila , Mansouri Parvin , Fateh Mohsen , Shirkavand Afshan
Published: December 2021

Introduction: Behçet’s disease (BD) is a debilitating and chronic vasculitis which can affect multiple organs. Recurrent oral aphthosis is the most common clinical feature of BD. The remarkable pain associated with painful oral ulcers can exert a major impact on the patients’ quality of life. Relieving pain of these oral ulcers is an essential approach in the management of mucocutaneous lesions of BD. Non-thermal CO2 laser therapy (NTCLT) as a novel photobiomodulative approach has recently been used for significant and immediate pain reduction of some types of painful oral lesions such as recurrent aphthous stomatitis, pemphigus vulgaris, and so on. In this procedure by some considerations, the conventional CO2 laser is used as a non-surgical, non- thermal, photobiomodulative laser without any visible thermal adverse effects. In this article, we report our experiences about the analgesic effects of NTCLT on painful oral aphthous ulcers of BD. Case Presentation: We report four cases of BD, whose painful oral aphthous ulcers were irradiated with NTCLT. Immediately after NTCLT, the pain of the lesions was significantly relieved with no visible complications. Conclusion: The results of this study suggest that NTCLT could be proposed as a hopeful procedure for significant and instant pain relief of oral aphthous ulcers of BD without any visible thermal adverse effects.
STUDY OF STEEL BARRIER SURFACE AFTER HIGH-SPEED EXPOSURE OF W AND TIC POWDERS
Authors: Petrov E. V. , Trofimov V. S. , Kopytskiy V. O.
Published: December 2021

The surface layer of an obstacle made of U8 steel is investigated after high-speed exposure to a flow of powder particles. After analyzing the frames of high-speed photography, the average velocities of movement of particles of tungsten and titanium carbide powders were determined. It is shown that the shock-wave loading of the barrier material and the effect of particles accelerated by the explosion energy provide a change in the physical and mechanical properties of the surface and the volume of the steel barrier material.
STRUCTURE AND PROPERTIES OF MELTED AREAS FORMED AT THE BORDER OF SECTION IN EXPLOSION WELDED JOINTS ALUMINUM-IRON-BASED ALLOY
Authors: Shmorgun V. G. , Kulevich V. P. , Bogdanov A. I. , Slautin O. V.
Published: December 2021

The influence of the composition of iron-based alloys on the microhardness of the areas of the melted metal in explosion-welded joints with aluminum is investigated. It is shown that, other things being equal, the presence of chromium in the composition of an iron-based alloy leads to an increase in the hardness of the alloys by 1-2 GPa, and joint alloying with chromium and nickel, by 3 GPa.
Göksu Irmağı (Türkiye) Güncel Balık Faunası ve Ekolojik Durumunun Değerlendirilmesi
Authors: KÜÇÜK Fahrettin , GÜLLE İskender , GÜÇLÜ Salim Serkan , TURAN Davut
Published: December 2021

Orta Toroslar karst alanlardan beslenen Göksu Irmağı, Doğu Akdeniz Havzası’nın Akdeniz’e dökülen en büyük akarsuyudur. Bu çalışmada, 2004-2017 yılları arasında farklı tarihlerde yapılan örneklem, gözlem ve literatür ışığında; Göksu Irmağı balık faunasının güncel taksonomik durumu, dağılım alanları, IUCN koruma ölçütleri ve akarsu bölgelerinin ekolojik yapısı değerlendirilmiştir. Çalışmamızda akarsuyun acısu bölgesi hariç 8 familyadan; 6’sı endemik olmak üzere 7’si yerli, 3’ü egzotik ve 1’i göçücü (diadrom) toplam 11 takson belirlenmiştir. Akarsuyun yukarı havzalarındaki bu yüksek endemizm oranı oldukça dikkat çekicidir. Irmağın ana kollarını oluşturan, yukarı-orta havza drenaj alanı içerisindeki, Göksu Çayı ve Ermenek Çayı (Gevne Çayı)’nın üzerinde gerçekleşen karayolu, köprü, baraj ve HES yapımı gibi fiziki tahribatların akarsu ekosisteminin doğal yapısını bozduğu, akarsu yatağında kısmi kurumalar ve habitat parçalanmasına neden olduğu gözlemlenmiştir. Bu baskılar sonucunda, Göksu Çayı ve Gevne Çayı’nın baskın balık türü olan endemik Toros sirazı (Capoeta caelestes) popülasyon yoğunluğunun önemli ölçüde azaldığı tespit edilmiştir. Aynı olumsuz etkenler nedeniyle Gevne Çayı’nın Beyreli Köyü (Hadim-Konya) ile Dumlugöze (Sarıveliler-Karaman) arasında kalan yaklaşık 45 km’lik üst kesiminde 2004-2009 yılları arsında nadiren örneklenen Kırmızıbenekli Alabalık (Salmo opimus) popülasyonunun yok olduğu belirlenmiştir.
Güney Doğu Karadeniz’de Beam Trol ile Avlanan Liocarcinus depurator (Crustacea: Decapod: Brachyura)’ün Üreme Biyolojisi
Authors: ONAY Hatice , BİLGİN Sabri
Published: December 2021

Bu çalışma Aralık 2012- Kasım 2013 ayları arasında Güney Doğu Karadeniz’de beam trol ile avlanan Liocarcinus depurator’un (Crustacea: Decapod: Brachyura) üreme özelliklerini belirlemek amacıyla yürütülmüştür. İyidere, Merkez ve Çayeli istasyonlarından 2 m genişliğinde kirişli trol (Beam trol) kullanılarak 0-30+ derinliklerde örnekleme yapılmıştır. Toplamda 2715 adet L. depurator (%39,4 yumurtasız dişi, %7,8 yumurtalı dişi ve %52,8 erkek) biyolojik olarak incelenmiştir.. GSI değerleri en yüksek dişide Ağustos- Kasım aylarında, erkeklerde ise Mart ayında tespit edilmiştir. Yumurtalı bireyler, Mayıs ve Kasım ayları arasında tespit edilmiştir. Araştırma bölgesinde L. depurator türünün yumurtlamasının Şubat, Mart ve Nisan ayları hariç yıl boyunca devam ettiği belirlenmiştir. %50 cinsi olgunluk erkekler için 32,28 mm (KG) dişiler için ise 28,19 mm (KG) olarak hesaplanmıştır. Çalışma sonuçları L. depurator türü üzerinde yapılacak daha sonraki çalışmalar için önemli girdi parametreleri olarak değerlendirilmiştir.
FAKTOR-FAKTOR YANG MEMPENGARUHI PEMILIHAN KARIR MAHASISWA S1 AKUNTANSI SEBAGAI AKUNTAN PUBLIK
Authors: Susanto Vania , Everrell Jeremy , Marsetio Nany Chandra , Hadi Achmad Setyo
Published: December 2021

This research aims to examine the effect of compensation, variety of work experiences, marketability, high turnover, work environment, subjective norms, difficulty to pursue CPA certification, intention to pursue CPA certification, extensive travel and internship experiences on the career choice of undergraduate accounting students as public accountants using theory of planned behavior and motivation theory. The sample was collected by using purposive sampling, resulting in 155 undergraduate students from 3 private universities and 3 public universities in Java Island. Logistic regression analysis is used with the help of SPSS 26. Interviews as a triangulation is conducted to understand the results better. Results show that compensation, subjective norms and intention to pursue CPA certification have a positive influence while  high turnover and extensive travel have a negative influence on the career choice of undergraduate accounting students as public accountants. The results of logistic regression also found that variety of work experiences, marketability, work environment, difficulty to pursue CPA certification and internship experiences have no influence on the career choice as a public accountant. This paper has important implications as a reference for future research, for the preparation of the accounting study program curriculum, as interview materials for the recruitment process, and for IAPI to socialize the CPA certification requirements.

 

Keywords: career choice, public accountant, theory of planned behavior, motivation theory
RANCANGAN WATERWALL PADA ONCE THROUGH SUPERCRITICAL BOILER UNTUK PEMBANGKIT LISTRIK TENAGA UAP KAPASITAS 1X660 MW
Authors: Jayu Suzia  , Ika Yuliyani  , Maridjo
Published: December 2021

Waterwall merupakan tempat terjadinya proses perpindahan panas konveksi dan radiasi antara fluida kerja dengan gas hasil pembakaran pada Furnace. Ada 3 jenis waterwall, yaitu multi-pass waterwall, spiral waterwall, dan Benson waterwall. Pada teknologi supercritical boiler, jenis waterwall yang paling banyak digunakan yaitu jenis spiral waterwall karena perpindahan panas yang terjadi lebih baik dari jenis yang lainnya dan juga mengurangi jumlah pipa yang digunakan pada boiler tersebut. Temperatur dan tekanan fluida kerja pada supercritical boiler beroperasi di atas titik kritis, titik kritis tekanan fluida air adalah sebesar 22,1 MPa dan titik kritis temperatur 374,14°C. Hssil rancangan waterwall adalah jenis spiral waterwall dengan volume furaace waterwall sebesar 2952i,36 m3, tinggi furnace waterwall sebesar 65,66 m,  lebar furnace waterwall sebesar 21,42 m, kedalaman fumace waterwall sebesar 20,99 m dan diameter luar water tubes spiral waterwall sebesar 76,2 mm (3 in) serta ketebalan pipa tersebut sebesar 1,27 nn (0,05 in). Jumlah energi kalor yang diserap oleh waterwall adalah 689.33 MW.
LINIERISASI SENSOR THERMISTOR NTC MENGGUNAKAN PERANGKAT LUNAK DENGAN METODE LOGARITMIK
Authors: Wahyu Budi Mursanto  , Hartono Budi Santoso  , Sri Utami
Published: December 2021

Hubungan resistansi termistor dengan temperatur merupakan fungsi eksponensial dan biasa dinyatakan dalam Persamaan Beta, namun relasi tersebut benar apabila temperatur yang digunakan adalah dalam satuan derajad Kelvin. Dalam penelitian ini akan dicari suatu relasi tegangan hasil pengukuran dengan temperatur, namun dalam satuan derajad Celcius. Untuk itu akan dicari suatu model matematik termistor yang mempunyai fungsi dengan karakteristik eksponensial yang memenuhi relasi lersebut.  Teknik linierisasi dilakukan dengan mencari fungsi invers dari model matematik tersebut yang merupakan fungsi logaritmik untuk mendapatkan kembali nilai temperatur yang diinginkan. Hasil penelitian memperlihatkan bahwa model matematik dengan fungsi Gompertz plus konstanta memberikan kecocokan yang paling sesuai antara model matematik dengan sebaran data. Dengan menggunakan metode linierisasi secara software menggunakan arduino diperoleh hasil ketelitian pembacaan temperatur yang paling baik dengan derajad kesalahan ±0,04°C pada rentang pengukuran 10°C sampai dengan 90°C.
Présentation
Authors: Damasco Denise Gisele de Britto
Published: December 2021

Présentation
Penerapan Model Pembelajaran Treffinger Pada Pembelajaran Geografi
Authors: Nurjannah Humairah , Saputro Alief , Maddatuang Maddatuang , Fikri Muh Jibran Nidhal
Published: December 2021

This study aims to determine whether the application of the Treffinger learning model can improve student learning outcomes in geography learning in class X SMA 7 Sinjai.  This research method uses pretest posttest control group design experimental research.  The subjects in this study were two classes of IPS X in SMA Negeri 7 Sinjai namely X IPS 1 and X IPS 2. The data analysis technique in the study used SPSS 22 for windows.  For the hypothesis test the t-test (independent samples t test) is used.  The results showed that the Treffinger model affected the learning outcomes in learning geography of class X IPS students of SMA Negeri 7 Sinjai.  This shows Ho was rejected and Hi was accepted.  The gain score of students' learning outcomes using the Treffinger model is better (8.97) than students who do not use the model (1.41).  Suggestions for teachers, the use of this learning model can be done as an alternative model to improve student learning outcomes.  Further research is also recommended to: a) test the effect of applying the Treffinger learning model to other variables and to locations, levels of education, or other material;  and b) integrate or compare with other learning models to be used as alternative learning models in schools.  Quasi (Quasi Experiment) with design.
Peningkatan Hasil Belajar Siswa Pada Pembelajaran Geografi Melalui Model Discovery Learning
Authors: Pratiwi Pratiwi , Zhiddiq Sulaiman , Umar Ramli , Saputro Alief
Published: December 2021

This study aims to: 1) find out how the picture of learning outcomes of students by using the Discovery Learning learning model in class X SMA Negeri 3 Luwu Utara. 2) find out the increase in geography learning outcomes by using the Discovery Learning learning model in class X SMA Negeri 3 Luwu Utara. The target in this study were students of class X IIS 2 in SMA Negeri 3 North Luwu, totaling 30 students. This type of research is Classroom Action Research (PTK). Consists of 2 cycles where each cycle consists of three meetings. The first and second meetings are material giving and the third meeting is the evaluation of the end of the cycle. The results of this study indicate 1) The average learning outcomes of students before using the discovery learning model is 40.67. Then increase after the application of discovery learning models in the first cycle of 63.267 included in the medium category, and in the second cycle of 75.33 also included in the medium category with a percentage increase of 13.79%. 2) The results of observations of students' activities in the teaching and learning process also increased, in the first cycle of the first meeting of 60.14% and then an increase in the second meeting of 68.88%. In the second cycle the first meeting amounted to 70.83% and experienced a change in the second meeting amounted to 78.47% included in the category of "very active".
Pengaruh Penggunaan Pupuk Bersubsidi terhadap Efektivitas Petani di Kelompok Tani Tosalamae Kabupaten Pinrang
Authors: Rais Muh , Yusriadi Yusriadi , Nurhaedah Nurhaedah
Published: December 2021

The purpose of this study is to find out the influence of the use of subsidized fertilizer on the effectiveness of farmers based on the right indicators of price, right amount, on time, right place, and the right type in the farmer group tosalamae. This research is descriptive quantitative. The method of data retrieval used is observation, questionnaire and interview. The method of data analysis used is multiple linear regression. Primary data comes from farmer interviews and secondary data comes from research-related agencies. The results showed that on time is a real effect on (Y) the effectiveness of the use of subsidized fertilizers because of the significance (Sig) below alpha (α) 0.05 ie 0.016 means a real effect on the use of subdivided fertilizers in farmer groups tosalamae. Subsidized fertilizer is very important for farmers in the process of farming, so when farmers want to use subsidized fertilizer is always available in the time farmers need it. Therefore, on time it is very important in the use of subsidized fertilizers.
Relationship Between Emotional Intelligence and Geography Learning Outcomes of Class XII Students at Wahdah Islamiyah Integrated Islamic High School Makassar
Authors: Abbas Ibrahim , Syarif Erman , Lisman Lisman
Published: December 2021

This study aims to determine whether there is a relationship between emotional intelligence and geography learning outcomes in class XII Islamic Senior High School Wahdah Islamiyah Makassar. This research is a type of quantitative research with the Spearman Rank correlation method. The data collection technique  uses a  questionnaire.  The  sampling  technique  in this study  used a saturated sampling technique with a total of 25 respondents. For learning outcomes data is taken from the grade XII student report cards in the geography subject. The results of the analysis of emotional intelligence data are included in the medium category with an average value = 107.84 at intervals 103–110, for geography learning outcomes are included in the low category with an average value = 83.52 at intervals 81-84, to prove whether or not there is a relationship between emotional intelligence and geography learning outcomes, it can be seen from the calculation obtained using the Spearman Rank correlation formula, where the value of rs =0.037, with a significant value of 0.861. Because sig > 0.05, it can be concluded that emotional intelligence does not have a significant relationship with geography learning outcomes and the relationship is included in the very low category.
fib Bulletin 100. Design and assessment with strut-and-tie models and stress fields: from simple calculations to detailed numerical analysis.
Authors: Passos Sério Lourenço Miguel Filipe , Fernández Ruiz Miguel , Haugerud Stein Atle , Blaauwendraad Johan , Bousias Stathis , Hoang Linh Cao , Mata-Falcón Jaime , Meléndez Gimeno Carlos , Mihaylov Boyan , Pedrosa Ferreira Miguel , Roubaty Quentin
Published: December 2021

Following the long-standing tradition of fib in promoting the use of consistent design methods, strut-and-tie models were formally incorporated in Model Code 1990 to serve as the design basis for discontinuity regions. This choice was largely acknowledged as a sound approach for design and was thereafter followed in many national standards. For Model Code 2010, some update and revision of the previous provisions was performed, but the scope of the method was particularly broadened by introducing its complementary use with the stress field method. Since Model Code 2010, significant new knowledge has been generated in this topic. Particularly, the use of software implementing the theoretical ground of the stress field method is becoming increasingly popular and efficient, allowing for design, optimisation and assessment of structures in a simple, transparent and accessible manner. In this Bulletin, the current state-of-the-art of the strut-and-tie models (STM) and the stress field models (SFM) is presented. Reference is not only made to classical rigid-plastic solutions, but also to solutions considering compatibility of deformations, such as elastic-plastic approaches or models allowing investigation of serviceability behaviour and deformation capacity of concrete structures. It is shown in the Bulletin that all models share the same ground and fundamental hypotheses. Their results are presented in a unitary and consistent manner by means of compression fields in the concrete and stresses in the reinforcement. The consistency amongst these approaches and their potential use in practice is also explored by means of the Levels-of-Approximation (LoA) approach as described in Model Code 2010. Another effort in this Bulletin has been devoted to provide comparisons of the solutions according to strut-and-tie and stress fields to tests, in order to discuss on their pertinence and limitations. This perspective is also completed with practical examples presented of structures actually designed with this technique and where the potential of these methods can be appreciated in a clear manner. Finally, a number of special topics are also covered in the Bulletin, related to numerical optimisation, verifications at serviceability states, minimum reinforcement or the applicability of the methods under cyclic or reversal actions. This Bulletin not only aims to give state-of-the-art rules and methods to design according to these techniques, but also to provide an outlook of how these methods could be implemented in future standards. This material also serves as the background document for the revision of the current provisions of Model Code 2010 in the new Model Code 2020.
Attainment of low subthreshold slope in planar inversion-channel InGaAs MOSFET with in situ deposited Al2O3/Y2O3 as a gate dielectric
Authors: Young L. B. , Liu J. , Lin Y. H. G. , Wan H. W. , Chiang L. S. , Kwo J. , Hong M.
Published: December 2021

We have demonstrated a record low 85 mV dec−1 subthreshold slope (SS) at 300 K among the planar inversion-channel InGaAs metal-oxide-semiconductor field-effect transistors (MOSFETs). Our MOSFETs using in situ deposited Al2O3/Y2O3 as a gate dielectric were fabricated with a self-aligned inversion-channel gate-first process. The temperature-dependent transfer characteristics showed a linear reduction of SS versus temperature, with the attainment of an SS of 22 mV dec−1 at 77 K; the value is comparable to that of the state-of-the-art InGaAs FinFET. The slope factor of SS with temperature (m) is 1.33, which is lower than those reported in the planar InGaAs MOSFETs.
Lensless dual-color fluorescence imaging device using hybrid filter
Authors: Kulmala Natcha , Sasagawa Kiyotaka , Treepetchkul Thanaree , Takehara Hironari , Haruta Makito , Tashiro Hiroyuki , Ohta Jun
Published: December 2021

In this study, a dual-band hybrid filter that achieves high excitation light rejection performance in a lensless imaging system was fabricated and incorporated into an imaging device. The hybrid filter consisted of interference and absorption filters, and a fiber optic plate (FOP). The interference filters were attached to both sides of the FOP, which was placed on top of the absorption filter to suppress the decrease in spatial resolution. In addition, the lamination order was optimized to achieve a high fluorescence observation performance. The fabricated hybrid filter was mounted on an image sensor and had the ability to indicate the green and red fluorescence components.
Resolution capability of resist patterns and throughput using alkaline treatment under ultrasonic irradiation
Authors: Onishi Hideto , Miyake Mikio , Shirai Hajime
Published: December 2021

Alkaline treatment of the photoresist under ultrasonic irradiation has been investigated to improve the resolution capability of resist patterns with higher throughput. The selectively dissolved phenol resin for the combination of the alkaline treatment with ultrasonic irradiation was increased by 2.3 times compared to the solely alkaline treatment. The sensitizing effect of naphthoquinone diazide (sensitizer) based on phenol was increased to 0.46 against dip treatment of 0.31. As a result, resist sensitivity was increased to 26% and the resolution capability was drastically improved. Consequently, the 0.5 μm line and space resist patterns were resolved completely with fine profile by using the photoresist with a 0.7 μm resolution limit together with g-line exposure machine with a 0.6 μm resolution limit. As a consequence, a high throughput of 25 wafers min−1 was achieved, which was more than 25 times higher than that of electron beam lithography.
Consequence of Covid-19 lockdown on household food security: Voices from Hoima City, Uganda
Authors:   Discipline of Public Administration and Management, Lira University, Lira, Uganda, Mwesigwa David
Published: December 2021

Abstract Purpose: To investigate the consequence covid-19 lockdown on food security among a cohort of peri-urban households in Hoima city. Research methodology: A descriptive survey was employed targeting 186 respondents. Data were collected using a researcher-designed self-administered questionnaire and analysed using quantitative statistics. Specifically, chi-square was employed to establish whether the hypothesis held sway; also, regression analysis was employed with a view of forecasting the degree of change in household food security due to covid-19 lockdown. Results: The period of lockdown announced and implemented by the government had a positive consequence on food security. Nonetheless, the economic hardships overturned the successes otherwise achieved as a number of households sold off much of the food so as acquire other household items. Recommendations: While the government is credited for instituting a lockdown as a means to reduce the spread of covid-19 virus, it is recommended that city authorities are encouraged to boost urban farming by distributing agri-inputs to households in the peri-urban seeing that their daily incomes are already constrained. Contribution: The findings of this study may be useful to city authorities in Uganda in evolving a guide on integration of food security as a cross-cutting issue in the overall strategic disaster management plan. This article makes an input to the budding field of understanding by underlining inroads that can generate more sustainable urban community livelihoods through food security.
Pemanfaatann E-Learning Bagi Guru MGMP PAI Pada Masa Covid-19 Di Kab. Bintan Kepulauan Riau
Authors: Hantoro Ramandha Rudwi , Vita Lestari Dwi , Ediyansyah Ediyansyah , Zulhamdan Zulhamdan , Sudanto Sudanto
Published: December 2021

Sejak merebaknya wabah pandemi corona virus disease (Covid-19) di seluruh dunia memaksa banyak sekolah di Indonesia melaksanakan pembelajaran secara online di rumah. Google salah satu aplikasi online yang memiliki banyak fasilitas yang dapat digunakan untuk pembelajaran untuk guru dan siswa secara online, diantaranya google meet dan google classroom. Google Meet dan google classroom menyediakan banyak fasilitas untuk pembelajaran yang aman dan mudah digunakan untuk komunikasi antara guru dan murid. Pengabdian kepada masyarakat bertujuan untuk mengenalkan media pembelajaran menggunakan google meet dan google classroom untuk digunakan pembelajaran online kepada guru Musyawarah Guru Mata Pelajaran Pendidikan Agama Islam (MGMP PAI) Kabupaten Bintan Kepulauan Riau. Pelatihan dilaksanakan secara daring menggunakan WA Grup yang diikuti oleh 30 orang peserta guru perwakilan dari seluruh SMP Kabupaten Bintan.
Graça Morais et José de Guimarães, des humanistes du 20 ème siècle: l’art de penser le monde par le voyage
Authors: Souto Egídia
Published: December 2021

Starting with the theme of travel and forced migration in the contemporary world, this work aims to reflect on the different forms of travel representations and state of the world in a resilience time. Specifically, we will analyse Metamorfoses da Humanidade (2018) of Graça Morais and Nómadas e Migrantes (2018) of José de Guimarães, to understand how these artists describe the humanity and the crisis of the migrants from the artifice of the image.
E-savjetovanja o propisima i planskim dokumentima o javnoj arhivskoj službi u Hrvatskoj
Authors: Bukvić Nenad
Published: December 2021

U članku su prezentirani rezultati istraživanja o sudionicima savjetovanja s javnošću (e-savjetovanja) o propisima i planskim dokumentima kojima se uređuju organizacija i obavljanje javne arhivske službe u Hrvatskoj. Podatci su prikupljeni metodom kvantitativne analize sadržaja pojedinačnih izvješća o provedenim savjetovanjima od 2017. do 2020. godine dostupnih na središnjem mrežnom portalu e-Savjetovanja i popratnih dokumenata. Nakon uvoda slijedi teorijski dio, u kojem je ukratko opisan normativni okvir provedbe e-savjetovanja u Hrvatskoj, arhivski propisi i planski dokument, o kojima je provedeno e-savjetovanje te metodologija istraživanja. Potom su prezentirani rezultati istraživanja te se o njima raspravlja. Prezentirani podatci o broju i strukturi sudionika (fizičke osobe, razne kategorije pravnih osoba) te broju komentara koje upućuju (ukupno i po pojedinom e-savjetovanju) interpretirani su kao važan pokazatelj zainteresiranosti društvene okoline za javnu arhivsku službu, odnosno rad državnih arhiva kojima je njezino obavljanje povjereno. S druge strane, sudjelovanje u e-savjetovanjima pojedinih strukovnih arhivističkih društava, državnih arhiva i njihovih administrativnih i stručnih djelatnika interpretirano je kao pokazatelj zainteresiranosti za jačanje normativne infrastrukture vlastite službe.
Kronika grba obitelji Fux iz Metlike (Chronik zum Wappens des Geschlechts Fux)
Authors: Lamprecht Rajmund
Published: December 2021

Autor članka obrađuje kroniku metličke obitelji Fux, s grbom, koja je u obiteljskom vlasništvu već nekoliko generacija i koja je bila općenito prihvaćena kao konačna činjenica. Autor je analizirao i provjerio podatke iz kronike te razjasnio tko je njezin autor i kakvim je prevarantskim metodama izigrao obitelj, sugerirajući da se radio plemićkoj obitelji. Istovremeno je objasnio sve bitne elemente u kronici, kao i izvor grba.