bluuebunny/crossref_metadata_2025 huggingface dataset:
LES INFECTIONS SUR PROTHESES DE HANCHE : QUELLE STRATEGIE THERAPEUTIQUE ?
Authors:   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Chaoui A. , Jiddi M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Nassiri M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Ayyadi H. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Elhaoury H. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Chafik R. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Madhar M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Najeb Y. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc.
Published: June 2022

As prosthetic hip infection is one of the most feared complications of hip arthroplasty, the aim of our work was, on the one hand, to describe different possible therapeutic options for treating and managing PHI, and on the other hand, to establish a strategy according to the type of infection and the characteristics of each patient. This is a retrospective study concerning 12 cases of prosthetic hip infection, conducted at the Department of Orthopedic Surgery and Trauma (A) of the Ibn Tofail Hospital in Marrakech and the Grand Atlas Clinic, during a period ranging from January 2017 to December 2020. The average age of our patients was 63 years, with a predominance of women (66% of cases). The distinction of PHI from other causes of painful hip arthroplasties is not obvious, therefore its diagnosis is based on a cluster of arguments clinical, radiological and biological pre and intraoperative. We were able to divide our patients according to the type of infection, 41.6% had an early postoperative infection and 58.4% had a delayed chronic infection. This classification as well as the particularities of each patient allowed us to choose the optimal therapeutic strategy and to adapt it according to the evolution of the infection. Indeed, targeted antibiotic therapy, in association with surgery, is essential. Thus, preservation of the prosthetic implant is indicated in early infections (< 4 weeks), while its change is reserved for delayed chronic infections. At the end of this study, we were able to establish a medico-surgical therapeutic strategy adapted to our service and the practical recommendations for the management of infections on prostheses.
LIPOSARCOME DE BAS GRADE ET PIEGE DIAGNOSTIC: A PROPOS DUN CAS
Authors:   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Chaoui A. , Nassiri M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Jiddi M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Ali Robleh S. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Elhaoury H. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Madhar M. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Rachid C. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc., Najeb Y. ,   Service De Traumatologie-Orthopedie A, Faculte De Medecine Et De Pharmacie Cadi Ayyad, Hopital Ibn Tofail, CHU Mohamed VI, 40000 Marrakech, Maroc.
Published: June 2022

Le liposarcome est lun des plus communs sarcomes des tissus mous, il represente pres dun quart des neoplasmes des parties molles. Cependant cest un cancer rare puisquil ne represente quenviron 10% de lensemble des cancers chez lhomme. Nous rapportons le cas dun jeun patient de 36 ans, presentant une masse de la face antero-externe de la cuisse gauche de consistance molle, douloureuse, mobile par rapport au plan superficiel, sans signes inflammatoires en regard, de 12cm du grand axe, evoluant depuis 2 mois dans un contexte de conservation de letat general. Le bilan biologique standard etait normal. La radiographie de la cuisse gauche na pas revelee danomalies osseuses ni de calcifications au niveau des parties molles. Ces caracteristiques evoquaient un lipome dont lexerese a ete programmee. Letude anatomopathologique et immunohistochimique de la piece operatoire ont objective un liposarcome peripherique bien differencie de bas grade appele aussi tumeur lipomateuse atypique (OMS 2013) (Grade 1 selon FNCLCC). Un bilan dextension a ete realise fait dune IRM de la cuisse gauche etait negatif. En accord avec le comite doncologie de notre CHU, une intervention de reprise dexerese a ete realisee elle a consiste en une excision de la cicatrice precedente puis, en bloc, de laponevrose et du tissu musculaire sur toute la hauteur du site initial de la tumeur en le debordant de deux centimetres environ. Une surveillance clinique locale et regionale post-operatoire du patient a 4,6 mois et un an plus trad na pas revelee danomalie.
PERIPHERAL OSSIFYING FIBROMA - A CASE REPORT
Authors:   Assistant Professor, Sri Rajiv Gandhi College of Dental Sciences., Prakash Nomitha , Karanjkar Mehta Abha ,   Assistant Professor, Bapuji Dental College and Hospital., Bommineni Prathima ,   Assistant Professor, Krishnadevaraya College of Dental Sciences., Prathim Roy Partha ,   Associate Professor, Sri Rajiv Gandhi College of Dental Sciences.
Published: June 2022

Peripheral ossifying fibroma is a benign neoplasm that usually develops from gingiva, presenting as an exophytic smooth surfaced pink or red nodular mass that is sessile or is less frequently seen on a pedicle. From the Indian perspective, it is usually noticed in 5thâ€“6th decades of life with female predilection. Microscopically, the tumour shows stratified squamous epithelium and highly cellular fibrous stroma, sparse endothelial proliferation with fibroblasts and dystrophic calcifications. It has to be differentiated histopathologically from pyogenic granuloma, fibroma, peripheral giant cell granuloma, peripheral odontogenic fibroma and fibrous hyperplasia. A case of peripheral ossifying fibroma of mandibular gingiva in a 70-year-old Indian woman is reported.
DEVELOPMENT OF LIFE SKILLS THROUGH VARIOUS FORMS OF FOLKLORE PEDAGOGY AT ELEMENTARY LEVEL OF EDUCATION
Authors:   Head and Dean Faculty of Education, Department of Education, University of Jammu., Nanda Renu , Kour Raspreet ,   Research Scholar of Department of Education, University of Jammu.
Published: June 2022

Every society of the world has an important duty to provide basic education to all their members so that they can lead an effective life. Especially the elementary level of the education is a period when the intellectual,moral, social, physical, emotional and almost all the capabilities are very high during this time but most of the students are not able to utilize their potential to maximum. A life skills education bridges the gap between ones basic functioning and capabilities. It strengthens ones ability to meet the needs and demands of the present society and develops the skills needed to deal with todays realities and challenges.Our conventional classroom pedagogy deprives children opportunities to learn in a collaborative and reflective manner. But with the help and usage of various form of folklore pedagogy like folk stories, riddles, myths, legends, fairy tales, celebration of folk culture, celebration of traditional food habits of different societies in the class room, we should inculcate various life skills among the students at elementary stage. The present research paper highlighted, how the various form of folklore pedagogy develops life skills among the students.
NEXUS OF UNIVERSITY AND COMMUNITY: TRANSFORMATIVE REFLECTION OF STUDENT VOLUNTEERS
Authors:   College Lecturer, University of Cebu-Lapu-Lapu and Mandaue, College of Teacher Education., A. Garma Vernel , L. Niepes Gendolf ,   College Lecturer, University of Cebu-Lapu-Lapu and Mandaue, College of Teacher Education.
Published: June 2022

To connect the university and community, this paper aimed to describe how the student volunteers gave meaning to their participation in the ALS Assistantship Community Extension program. Anchored on Edmund Husserls phenomenology, the researchers explored the experiences of 8 student volunteers, specifically the student interns, through their written transformative reflection journals. The result revealed 50 significant statements that generated 5 themes. These themes emphasize the experience of student volunteers in their participation in the community extension program of the department as 1.) Recognizing the highs and lows of the volunteers community experience 2.) Making strides toward becoming a dedicated individual 3.) Aligning oneself to the calling of the teaching profession 4.) Establishing nodes in the community through camaraderie, and 5.) Nurturing reflective practices toward excellence. These themes are further discussed through textural and structural descriptions. A description of the essence of student volunteers lived experience is provided. Results from this paper offered practical insights into improving the implementation of community extension programs in the department and ensuring that the volunteers participation truly enhanced learning.
EXOGENOUS OPTIMIZATION OF THE ANTIOXIDANT PROTECTION CAPACITY OF PLANTS IN MODERATE DROUGHT CONDITIONS
Authors:   Institute of Chemistry, Republic of Moldova., Anastasia Stefirta ,   Institute of Genetics, Physiology and Plant Protection, Republic of Moldova., Ion Bulhac ,   Institute of Chemistry, Republic of Moldova., Maria Cocu ,   Institute of Chemistry, Republic of Moldova., Lilia Brinza ,   Institute of Chemistry, Republic of Moldova., Vera Zubarev ,   Institute of Chemistry, Republic of Moldova.
Published: June 2022

The effect of Thiourea, Galmet and Thiogalmet on the antioxidant protection capacity of plants in moderate drought conditions was studied. Thiogalmet is a new chemical composition that contains Thiourea (Tu) and Galmet - a preparation that consists of a mixture of potassium, ammonium, magnesium gallates, and potassium molybdate and ammonium paramolybdate. Biological tests were performed in the vegetation complex of the Institute of Genetics, Physiology and Plant Protection. As subjects of investigations served the plants Glycine max (Merr) L Nadejda variety and Zeya mays LP458 cultivar, grown in the Mitcherlih vegetation pots with 40 kg soil and exposed to the drought stress at the critical stages for water. It has been established that pre-treatment of plants with Thiourea, Galmet and, in particular, with Thiogalmet increases the activity of superoxide dismutase (SOD), catalase (CAT), ascorbateperoxidase (APX), glutathione reductase (GLR) and glutathione peroxidase (GLPX). The high activity of antioxidant enzymes is associated with a decrease in the content of malonic di-aldehyde (MDA). The increase in antioxidant protection capacity of plants pre-treated with Thiogalmet was recorded both in optimal conditions and in conditions of oxidative stress induced by drought. Thiogalmet has been shown to be one of the new biologically active chemicals that can be used in agriculture to reduce the negative impact of oxidative stress caused by reactive oxygen species (ROS).
HUMANITIES IN HIGHER EDUCATION: THE ROLE OF THE UNIVERSITY OF GUYANA AS A PREMIER NON-PARTISAN INSTITUTION
Authors: Cayana Ele
Published: June 2022

Although Humanities in Higher education continues to be a subject that garners little institutional support, it is nevertheless tantamount to any other academic pursuit. Specifically, political philosophy and socio-economic nationality are subjects that have the potential to guide humanity into a balanced and sustainable future. In Guyana, the University of Guyana (UG) remains the premier academic institution and continues to maintain relevance and respect by being non-partisan. This essay attempts to reveal the context of this paradigm and suggests that the UGÂ’s mission and vision are needed now, more than ever. Teachers and students of Humanities will be responsible for coalescing a culturally divided society, manifesting a nation where collective wealth is paramount to individual successes. In this essayÂ’s commitment to social history, the use of Newspaper articles is paramount and reveals either public sentiment or, propaganda. Ultimately, though, the results show that there is an acknowledgment that UGÂ’s role will be tested in these times of economic change and, furthermore, that this is a defining moment for Guyanese to decide how development could transform all lives.
STUDY OF THYROID PROFILE IN GERIATRIC AND NON GERIARTIC DIABETES MELLITUS
Authors:   Department of General Medicine., Kumar Rahul Rajesh
Published: June 2022

Introduction: In clinical practice, diabetes mellitus (DM) and thyroid diseases are very common endocrine disorders. These are commonly affected by each other and association between both conditions have long been reported. Objective: To Study correlation and association between Thyroid disorder and Diabetes mellitus in geriatric and non geriatric age group patients. To study correlation between TSH and HBA1C in previously diagnosed Diabetes Mellitus patients. Method: The study includes 80 patients in geriatric age groups with type 2 diabetes mellitus visiting the Medicine out patients department. Thyroid profile were assayed A in type 2 diabetic patients. Results: It was noted that thyroid dysfunction was prevalent in 41(51.25%) A out of the 80 geriatric age group patients with 31(38.75%) being hypothyroidism, 7 (8.7%) having subclinical hypothyroidism and 3 (3.7%) having a hyperthyroid state. Conclusion: The study shows that screening should be strongly recommended for all type 2 diabetics to rule out thyroid dysfunction in patients with increasing age.
50 Years with Nordic Hydrology/Hydrology Research
Authors: Rosbjerg Dan
Published: June 2022

The history of Nordic Hydrology/Hydrology Research is described from its initiation in 1970 to its current state in 2021. This includes dramatic changes leading first to an ownership transformation to Nordic Association for Hydrology (NAH) in 1976, and much later, in 2004, to a joint ownership between NAH, British Hydrological Society and IWA Publishing. The development in publication policy during time is covered as well.
Thiomethylphenyl Benzenesulfonamides as Potential Cholesteryl Ester Transfer Protein
Inhibitors: Synthesis, Molecular Modeling and Biological Evaluation
Authors: Khalaf Reema Abu , Asa'ad Manal , Habash Maha
Published: June 2022

Background:

The number of lipid disorders cases has risen dramatically around the
world as a result of poor dietary habits, hereditary risk factors, or other diseases or medicines.
Cholesteryl ester transfer protein (CETP) is a 476 amino acid lipophilic glycoprotein that
helps transport cholesteryl esters and phospholipids from proatherogenic LDL and VLDL to
atheroprotective HDL. CETP inhibition increases HDL cholesterol, lowers LDL cholesterol
and triglycerides, rendering it a promising therapy option for hyperlipidemia and its comorbidities.

Methods:

In this research, fourteen benzenesulfonamides 7a-7g and 8a-8g were synthesized
and identified using 1H-NMR, 13C-NMR, IR and MS. The in vitro biological evaluation of 7a-
7g and 8a-8g revealed CETP inhibitory activities ranging from 15.6 to 100% at 10 μM concentration.

Results:

Four aromatic rings compounds bearing either m-CH3 (8c) or p-Cl (8g) were the most potent compounds
with 100% CETP inhibition, while the most active compound was 7c bearing three aromatic rings and m-CH3 with
an IC50 of 0.12 μM. LibDock displayed that benzenesulfonamides can form hydrophobic interactions with the side
chains of Leu129, Cys13, Ala202, Val198, Leu217 and Ile215 and participate in п-п stacking with Phe441, Phe197
and Arg201 in the binding pocket of CETP.

Conclusion:

Pharmacophore mapping showed significant matching with the pharmacophoric features of Hypo4/8
and shape-complemented Hypo4/8 of CETP inhibitors for potent compounds.
Detection of Iturin A from Bacillus atrophaeus by HPLC and Mass Spectrometry
Analysis and Evaluation of its Antifungal Activity
Authors: Pisheh Solmaz Moghtadi , Madani Mahboobeh , Shakib Pegah
Published: June 2022

Background:

Bacillus species create several kinds of metabolites, which contain cyclic
lipopeptide-type antibiotics, consisting of three major families: fengycin, surfactin, and iturin. Iturin
demonstrates powerful biocontrol characteristics and can restrain the growth of a diversity of plant
fungal pathogens.

Objective:

The current study investigates the identification of iturin A from Bacillus atrophaeus using
HPLC and Mass spectrometry analysis and evaluate its antifungal effects.

Materials and Methods:

In this study, the lipopeptide antibiotics were isolated by HPLC and characterized
by MS. Then, the lipopeptides were examined for their ability to antagonize the growth of different
pathogenic fungi. Antifungal performance of the lipopeptides was determined against Fusarium
oxysporum, Aspergillus niger, Penicillium chrysogenum, and Mucor hiemalis according to well diffusion
and percentage of growth inhibition.

Results:

Bacillus atrophaeus HNSQJYH170, isolated from Isfahan soil, offered strong fungicidal activity
by producing cyclic lipopeptide-type antibiotics. Inhibition zones were 17.55, 17, 18.50, and
20.99 mm, and the percentages of growth inhibition were 78.54, 62.55, 83.11, and 84/95 for Fusarium
oxysporum, Penicillium chrysogenum, Mucor hiemalis and Aspergillus niger, respectively. The spectrum
represented the iturins family in retention times of 32.423–33.893 min. MS demonstrated molecular
ion peaks (M+H) + for iturin at m/z 1029.55, 1043.60, 1051.55, 1065.60, 1079.60 and 1093.65.
The inhibition rate against all fungi on the seventh day of incubation was higher than 80%. Among
them, Aspergillus niger was the most sensitive fungal species with an average of 84.95% inhibition.

Conclusion:

According to the results, Bacillus atrophaeus HNSQJYH170 could operate as a biocontrol
agent against a wide spectrum of pathogenic fungi.
Efficacy and Safety of Lobaplatin-TACE in the Treatment of Primary Hepatocellular
Carcinoma: A Retrospective Study
Authors: Lu Haohao , Zheng Chuansheng , Liang Bin , Xiong Bin
Published: June 2022

Purpose:

To investigate the safety and efficacy of lobaplatin-TACE in the treatment of primary hepatocellular carcinoma.

Method:

The data of 536 patients who underwent TACE in the interventional department from January 2016 to January 2020 were collected. Patients were divided into two groups according to the chemotherapeutic drugs used in TACE.: epirubicin-TACE group(N = 260), lobaplatin-TACE group(N = 276). Primary study endpoint: (1) The tumor response after TACE; (2)The survival rates ; Secondary study endpoints:(1)Changes of liver function and blood routine before and after TACE;(2)Occurrence of post-embolization syndrome and infection after TACE.

Results:

The ORR was 35.0% in epirubicin-TACE group and 51.1% in lobaplatin-TACE group(P=0.001). The DCR was 73.1% in epirubicin-TACE group and 82.2% in lobaplatin-TACE group(P=0.011). The 6-month, 9-month, 12-month, and 15-month survival rates were higher in the lobaplatin-TACE group than in the epirubicin-TACE group(P=0.029,P=0.001,P=0.005,P=0.002). mOS: Epirubicin-TACE group,14.8 months; Lobaplatin-TACE group,18.6 months (P =0.007). mPFS: Epirubicin-TACE group,9.5 months; Lobaplatin-TACE group,12.8 months (P =0.000). There was no statistical difference in ALT, AST, total bilirubin and Leucocyte after TACE between the two groups (P=0.343,P=0.368,P=0.288,P=0.359). The platelet decrease after TACE was more significant in the lobaplatin-TACE group than in the epirubicin-TACE group (P=0.046). There was no statistical difference in the incidence rate of abdominal pain, fever and infection after TACE between the two groups (P=0.502,P=0.602,P=0.726).The incidence of vomiting after TACE in the lobaplatin-TACE group was higher than that in the epirubicin-TACE group (P=0.003).

Conclusion:

Lobaplatin-TACE has higher tumor response rate and survival rate.Lobaplatin-TACE is a safe and effective treatment strategy,it is worthy of clinical application.
Cannabidiol Successful Therapy for Developmental and Epileptic Encephalopathy Related to CYFIP2
Authors: de Góes Fernanda Veiga , de Andrade Ramos Jessyca Thays Melo , da Silva Fontana Rosiane , de Carvalho Serão Cassio Luiz , Kok Fernando , Gandelman Horovitz Dafne Dain
Published: June 2022

Background:

The knowledge about the molecular basis of epilepsies has increased enormously with the advent of next-generation sequencing (NGS) technology, and CYFIP2 is one of the many genes recently recognized and associated with epilepsy. Pathogenic variants in CYFIP2 cause Developmental and Epileptic Encephalopathy 65 (DEE65), which is characterized by hypotonia, profound developmental delay, and epilepsy.

Case Presentation:

Herein, we report a 3-year-old male with an early onset epileptic encephalopathy (Ohtahara syndrome) evolving to Lennox-Gastaut syndrome refractory to several antiseizure medications. Whole exome sequencing (WES) disclosed a heterozygous pathogenic variant p.(Arg87Cys) in CYFIP2, which occurred as a de novo event. After the introduction of cannabidiol, the patient remained seizure-free for 16 months and had a marked electroencephalographic improvement.

Conclusion:

Cannabidiol might be a therapeutic option for CYFIP2-related epilepsy
General Practitioners’ Experiences of Professional Uncertainties Emerging from the Introduction of Video Consultations in General Practice: Qualitative Study
Authors: Nordtug Maja , Assing Hvidt Elisabeth , Lüchau Elle Christine , Grønning Anette
Published: June 2022

Background

Uncertainties are omnipresent in health care, but little is known about general practitioners’ (GPs) professional uncertainties concerning digital consultations. This is problematic, as many countries have undergone an extensive digital transformation.

Objective

The aim of this study was to explore the professional uncertainties that emerged among Danish GPs with the introduction of video consultations.

Methods

We conducted qualitative interviews with 15 Danish GPs during the beginning of the COVID-19 pandemic in 2020. The interviews were analyzed using an abductive approach.

Results

We identified 3 categories of uncertainty: integrity, setting, and interaction. Respectively, these 3 categories of uncertainty refer to (1) uncertainties related to how technology may impede the provision of health care; (2) uncertainties related to the potentials of video technology; and (3) uncertainties related to how the video consultation technology affects interactions with patients.

Conclusions

The uncertainties experienced by Danish GPs appear to be a typical reaction to the introduction of new technology. Embedding video consultation technology into GPs’ working routines will take time, and GPs do not necessarily feel intuitively capable of transferring their abilities, such as being good and socially present for video-mediated consultations. The heterogeneity of professional uncertainties experienced among the GPs suggests that they are the product of individual GP-technology relationships—not of the technology in itself. Consequently, we cannot expect that uncertainties can be remedied by changing or precluding new technology.
Safe use of ibuprofen in COVID-19 in children
Authors: Borysova T.P.
Published: June 2022

The literature review presents current data on the use of ibuprofen in COVID-19. Features of оmicron-variant of the disease are presented, which, unlike previous outbreaks, has a very high level of transmission, shorter average incubation period, increased incidence among children. Because most children have mild to moderate COVID-19, nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, are the most commonly used drugs in childhood to relieve pain and fever. During the first outbreak of COVID-19, NSAID and ibuprofen have been suggested to be dangerous for use in COVID-19 because they may increase the risk of severe and fatal COVID-19 disease. Experimental and clinical data on the safe use of ibuprofen in COVID-19 are presented. To date, there is no increased risk of COVID-19 infection with ibuprofen. In addition, there was no increased risk of hospitalization or severe COVID-19, death of patients taking ibuprofen. A lower risk of death has been found in patients with COVID-19 who received NSAIDs, consistent with a reduction in inflammation and a cytokine storm in severe COVID-19 and a protective role for NSAIDs. According to the Protocol ”Provision of medical care for the treatment of coronary heart disease (COVID-19)“ in mild to moderate disease in children, symptomatic treatment of fever and pain with ibuprofen is indicated. Thus, according to WHO guidelines and available clinical data, ibuprofen can be safely used for analgesic and antipyretic effects in children with COVID-19.
Urban Form and Transportation Energy Consumption in Depok, Indonesia
Authors: Putri Devina Widya , Indradjati Petrus Natalivan
Published: June 2022

By combining transportation energy use per capita for main, side, and weekend activities, this study explores the correlation between transportation energy consumption and urban form at a village scale. Conducted in Depok, a satellite city of the Jabodetabek metropolitan area, Indonesia, four different urban form variables were measured, including population density, land use mix, street connectivity, and public transportation range area. Four other socio-economic variables, i.e., private vehicle ownership, driving license ownership, job type, and monthly income, were also considered in the analysis. Data on individual energy consumption in the transportation sector was acquired through an online questionnaire. The results of correlation analysis and one-way analysis of variance highlighted three main findings related to transportation energy consumption. First, the population density and the street connectivity were found to be correlated with the amount of transportation energy consumed. Second, the middle urban form compactness level outweighed the high compactness level in terms of energy consumption per capita per week. Finally, differences in private vehicle ownership, driving license ownership, and job type resulted in different transportation energy usage.
Investigation of a Relation between Radiogenic Heat Production Rate (RHPR) and Land Surface Heat Temperature (LST) from Thermal Bands of ASTER and Landsat-8 (TIR-Data): Case Study of West Ras Gharib area North Eastern Desert, Egypt
Authors: Abdeen Samah Saeed , Abd El Nabi Sami Hamed , El Manawy Moataz El said , El-Arafy Reda Esmat , Farag Karam Samir
Published: June 2022

In this paper, an attempt was tried to study the relation between the land surface heat temperature (LST), extracted, from the thermal emission infrared data (ASTER-TIR) and (Landsat-8-TIR) imagery and radiogenic heat production rate (RHPR) that calculated from airborne gamma-ray spectrometric data applied on west Ras Gharib area at Northeastern Desert of Egypt. The area is geologically covered mainly by Precambrian basement rocks, which are unconformably overlain by Phanerozoic sedimentary succession. The method used for extraction land surface heat temperature for both ASTER-TIR and Landsat-8-TIR images is the reference channel emissivity technique and founded as the best method comparing to others. The study results showed a relative higher RHPR threshold value reached 4.8 μW/m3. On the other hand, ASTER-TIR Land Surface Temperature (AST-LST) ranges between 27.64oC to 47.2oC and, the Landsat 8-TIR Land Surface Temperature (LS8-LST) ranges between 30.64oC to 50.68oC. Comparing all results, there were a weak relationship or to some extent parallel relation between RHPR and satellite LST; as when the value of the Y-axis is constant, there are multiple values on X-axis, so it is not possible to deduce the value of one variable in terms of the other. The poor relation is regarded to the very weak RHPR which is not enough to affect the surface heat temperature, emission that could be detected by both thermal sensors of ASTER and Landsat-8 satellite TIR data. Other factors such as: topography, wind, shading and scattering, rock moisture and density, can strongly affect the surface temperature. In conclusion, the output results could be improved in areas of very high radioelement concentrations especially 235U, and through the use of the enhanced spatial resolution of future satellite TIR imaging instruments.
Metode Pembelajaran Mesin untuk Memprediksi Emisi Manure Management
Authors: Widi Hastomo  , Nur Aini  , Adhitio Satyo Bayangkari Karno  , L.M. Rasdi Rere
Published: June 2022

Indonesia berkomitmen menurunkan emisi gas rumah kaca (GRK) melalui skema nationally determined contribution (NDC). Target yang hendak dicapai untuk menurunkan emisi GRK yaitu 29% melalui skema business as usual (BAU) atau 41% dengan bantuan internasional. Target ambisius ini membutuhkan transformasi, baik dalam sistem energi maupun sistem pangan dan tata guna lahan, yang perlu mengatasi potensi pertukaran di antara sejumlah besar target, seperti ketahanan pangan, ketahanan energi, menghindari deforestasi, konservasi keanekaragaman hayati, persaingan penggunaan lahan, serta penggunaan air tawar. Mitigasi dan adaptasi memiliki peran yang saling melengkapi dalam merespons perubahan iklim yang dilakukan pada skala temporal dan spasial. Makalah ini bertujuan untuk melakukan simulasi dan prediksi pada emisi manure management penghasil CO2eq dengan menggunakan metode pembelajaran mesin long short-term memory (LSTM) dan gated recurrent unit (GRU). Arsitektur lapisan tersembunyi yang digunakan berjumlah enam kombinasi, sedangkan dataset diperoleh dari repositori fao.org. Optimizer yang digunakan dalam makalah ini yaitu RMSprop, dengan graphical user interface menggunakan dashboard Streamlit. Hasil dari penelitian ini yaitu; (a) cattle dengan lima belas epoch menggunakan lapisan tersembunyi empat kombinasi (LSTM, GRU, LSTM, GRU) menghasilkan RMSE 450,601; (b) non-dairy cattle dengan lima belas epoch dan satu lapisan tersembunyi (GRU, GRU, GRU, GRU) menghasilkan nilai RMSE 361,421; (c) poultry birds dengan nilai dua belas epoch dan tiga lapisan tersembunyi (GRU, GRU, LSTM, LSTM) menghasilkan nilai RMSE 341,429. Tantangan yang dihadapi adalah penentuan epoch, kombinasi lapisan tersembunyi, serta karakteristik dataset yang berjumlah relatif sedikit. Hasil dari penelitian ini diharapkan dapat memberikan nilai tambah untuk mengembangkan alat dan model pendukung keputusan yang lebih baik untuk menilai tren emisi di sektor peternakan serta untuk mengembangkan strategi mitigasi emisi CO2eq yang mengarah pada praktik pengelolaan pupuk yang berkelanjutan.
Pengembangan Hypermedia Learning Environment (HLE) untuk Meningkatkan Self-Regulated Learning Berdasarkan Kemampuan Self-Monitoring
Authors: Intan Sulistyaningrum Sakkinah  , Rudy Hartanto  , Adhistya Erna Permanasari
Published: June 2022

Penggunaan media pembelajaran saat ini telah berkembang pesat. Dewasa ini banyak penelitian yang menggunakan komputer sebagai media pembelajaran yang adaptif bagi mahasiswa; salah satu contohnya adalah hypermedia learning environment (HLE). Media HLE dikembangkan untuk membantu mahasiswa dalam belajar, misalnya pada situasi pandemi COVID-19 saat ini, yang mengharuskan semua aktivitas pembelajaran dilakukan secara daring (online). Salah satu bidang yang terkena dampak pandemi ini adalah bidang pendidikan, yaitu semua kegiatan pembelajaran dialihkan menjadi daring. Oleh karena itu, pembelajaran berbasis web HLE dapat membantu mahasiswa untuk tetap belajar dari rumah. HLE saat ini sedang dikembangkan untuk meningkatkan kemampuan mahasiswa dalam proses self-regulated learning (SRL). Ada komponen penting di dalam SRL, yakni self-monitoring. Namun, dalam perkembangannya, HLE yang dikembangkan tidak berbasis self-monitoring. Dalam penelitian ini, HLE adaptif dikembangkan berdasarkan kemampuan self-monitoring mahasiswa. Dalam pengembangannya, sistem HLE menggunakan metode pengembangan agile, yaitu Scrum. Pengumpulan data awal untuk klasifikasi mahasiswa dilakukan menggunakan self-regulatory inventory (SRI). SRI merupakan instrumen yang digunakan untuk mengukur kemampuan self-monitoring mahasiswa. Data kemudian diolah hingga dapat mengklasifikasikan siswa menjadi tiga kelas, yaitu high, medium, dan low. Hasil klasifikasi kemampuan siswa kemudian digunakan untuk mengembangkan bantuan pembelajaran pada HLE. Pengembangan bantuan yang disediakan adalah dalam bentuk teks dan video yang disesuaikan dengan tingkat self-monitoring mahasiswa. Dari hasil pengembangan, didapatkan bahwa semua fungsi HLE dapat berjalan dengan baik. Sistem diuji coba kepada dua belas mahasiswa untuk mengetahui tingkat usability dengan menggunakan system usability scale (SUS). Hasil menunjukkan kategori good, dengan skor 72,92. Untuk penelitian selanjutnya, dapat dilakukan implementasi pada mahasiswa dan mengukur keefektifan sistem yang telah dikembangkan.
Aspects Related to Breastfeeding in Premature Newborns: A Literature Review
Authors: Siqueira Debora Albuquerque da Silva , Oliveira Letícia Victória Sindeaux de , Silva Lorenna Vidal Rodrigues da , Teixeira Paula Raimunda Araújo , Silva Luisa Margareth Carneiro da
Published: June 2022

Exclusive breastfeeding for premature newborn babies faces several challenges in order to be effective and to be able to offer the necessary benefits. This article was based on the selection of 13 studies related to breastfeeding and prematurity found in Scielo, CAPES and BVS in the last six years, which passed inclusion and exclusion criteria. The search was performed using the descriptors: breastfeeding, premature and preterm. It was concluded that the relationship between exclusive breastfeeding and preterm newborns may have difficulties in establishing itself, mainly due to factors related to maternal intention to breastfeed, support from family and health professionals, education, presence of the partner and among others. In addition, there was a lack of essential guidelines and the performance of a multidisciplinary team so that breastfeeding between mothers and their children was effective.
Resignificación cultural: adaptación de las mujeres rarámuris a la ciudad de Chihuahua
Authors: Ruiz Salazar Grissel Alejandra , Zapata Martelo Emma María , Martínez Corona Guadalupe Beatriz , Pérez Hernández Luz María , Arras Vota Ana María , Garza Bueno Laura Elena
Published: June 2022

Objetivo: explorar la resignificación cultural, los cambios ideológicos, de creencias, prácticas, costumbres identitarias, ritualidad religiosa, educación, dinámica familiar y matrimonio de las mujeres rarámuris cuando emigran de su entorno rural a la ciudad de Chihuahua en busca de mejores oportunidades. Metodología: con base en una metodología feminista, se da voz a 19 mujeres rarámuris cuyos testimonios fueron recabados en diversas entrevistas. Resultados: es evidente la necesidad de desarrollar estrategias e instrumentos sociales que, además de mejorar la calidad de vida de dichas mujeres, contribuyan a preservar algunos rasgos culturales de su comunidad. Conclusiones: se explica hasta qué punto la forma de vida de la zona urbana incide en las costumbres de las rarámuris y en su concepción de la realidad y la supervivencia, sobre todo de las nuevas generaciones.
Analysis of Transformative Learning Experience Through Teacher Learning Community Activities: Focusing on the Changes That Appeared in the Process of Ki Hyungdo Project
Authors: Jang Mi Sung , Kim Kyung Yee
Published: June 2022

(Jang, Mi Sung);
Depressão e qualidade de vida em docentes de uma universidade federal do sul do país
Authors: Machado Thayla Rauch , Almeida Letícia Maria da Silva , Dumith Samuel C.
Published: June 2022

A depressão é causa muito frequente de incapacidade, está associada à diminuição da produtividade e do desempenho no trabalho, limitando a contribuição social do portador de seus sintomas e causando um impacto negativo na vida do indivíduo. Os docentes fazem parte de uma categoria de profissionais expostos aos riscos psicossociais, aos fatores desencadeantes de estresse próprios da organização acadêmica e escolar e a situações em que se desequilibram as expectativas individuais do profissional e a realidade do trabalho diário. O objetivo deste estudo é verificar a associação entre depressão e qualidade de vida nos docentes universitários, por meio de uma pesquisa transversal e quantitativa, feita com docentes de uma universidade federal. A qualidade de vida foi analisada por um questionário, enviado por e-mail aos participantes, denominado The Medical Outcomes Study 36 – item Short Form Health Survey (SF-36), e a depressão pelo diagnóstico médico autorreferido; demais variáveis foram analisadas por questionário semiestruturado. Para análise estatística, utilizou-se o teste de análise de variância. A amostra contou com 270 de 680 (40%) professores. A prevalência de depressão foi de 6,3% (IC95% 3,4 a 9,2). Houve associação entre depressão com menor escore de qualidade de vida para os domínios capacidade funcional, dor, estado geral de saúde, vitalidade, aspectos sociais e saúde mental. Os demais domínios não atingiram significância estatística. Observou-se que a depressão influenciou de forma negativa a qualidade de vida dos professores universitários estudados.
Uso de chupeta e a interrupção do aleitamento materno exclusivo: estudo de coorte
Authors: Morais Suelly Pinto Teixeira de , Oliveira Abdias Medeiros de , Pinto Elizabete de Jesus , Vieira Graciete Oliveira , Oliveira Romario Carneiro de , Oliveira Vinicius Carneiro de
Published: June 2022

Este estudo se propôs a averiguar a existência de associação entre o uso de chupeta e a interrupção precoce do aleitamento materno exclusivo (AME) ao longo dos quatro primeiros meses de vida da criança. Para isso, utilizaram-se dados de uma coorte composta por 1.037 mães e crianças. Para estimar a associação entre a variável desfecho e aquelas de exposição ao longo do tempo, foi utilizada a técnica de Equação de Estimação Generalizada (GEE). Foi averiguado que a interrupção precoce do AME e o uso de chupeta aumentaram gradativamente conforme a idade da criança; no quarto mês, mais da metade das crianças já estava desmamada e fazia uso de chupeta. Os resultados da estimativa obtida por meio da GEE mostraram que permaneceu significativo apenas o uso de chupeta associado à baixa escolaridade materna como risco de interrupção precoce do AME, quando ajustado para as demais covariáveis. Os resultados reforçam a interferência negativa do uso da chupeta na duração do AME e a necessidade de informar às mães sobre as desvantagens do uso de chupetas.
L’accès à l’accompagnement et à la représentation par les personnes accidentées ou malades du travail : une analyse sous le prisme des coûts de la justice
Authors: Gesualdi-Fecteau Dalia , Visotzky-Charlebois Maxine
Published: June 2022

Au Québec, les personnes ayant subi un accident du travail ou souffrant d’une maladie professionnelle au sens de la Loi sur les accidents du travail et les maladies professionnelles sont susceptibles de cheminer dans un processus de contestation devant le Tribunal administratif du travail. Le présent article fait état de résultats de recherche mettant en lumière les défis en matière d’accès à l’accompagnement et à la représentation auxquels les personnes non syndiquées peuvent faire face, que celles-ci soient admissibles à l’aide juridique ou non. Si le Québec se démarque du reste du Canada relativement à l’accès à la représentation des personnes salariées non syndiquées en matière de normes du travail, force est de constater qu’il fait piètre figure quant au soutien et à l’assistance fournie aux personnes accidentées ou malades du travail. En effet, ces dernières font face à des écueils importants en matière d’accès à la représentation et à l’accompagnement. Pourtant, le fait d’être représenté ou accompagné semble avoir des avantages indéniables pour les personnes accidentées ou malades du travail cheminant dans ce processus judiciarisé.
GC-MS Analysis of the in vitro leaf derived Callus Extracts of Ichnocarpus frutescens (L)W.T.Aiton
Authors: Ashwini  , Rajanna L.
Published: June 2022

Medicinal plants are the treasure house of secondary metabolites. Production of seconmdary metabolites through micro propagation technology has immense application in new drug discoveries. Ichnocarpus frutescens (L.) W.T. Aiton - is a latex secreting medicinal herb commonly known as black creeper or Krishna Sariva belonging to the family Apocyanaceae.The present study was aimed at induction of callus from the leaf explants of I. frutescens using Murashige and Skoog (MS) medium supplemented with various combinations of plant growth regulators. Maximum amount of green compact mass of callus was proliferated from leaf explants on MS medium fortified with 3mg/L NAA + 2mg/L BAP. The main objective of the present study was to investigate the secondary metabolites in different extracts of callus by GC-MS analysis. To our best knowledge, no literature is available and this is the first report on GC–MS analysis of leaf derived callus extracts, which showed the presence of different phytocompounds out of which, Stigmasterol, Hexadecanoic acid, Beta-Sitosterol, Stigmasta-3,5-dien-7-one and Heptacosane are the major compounds that found to possess a wide range of biological activities. This protocol could be used to identify the secondary metabolites from leaf derived callus of the I. frutescens and further studies have to be carried out for the isolation and characterization of novel compounds for the formulation of new pharmaceutical drugs and also for its commercial production which will be used to cure some important ailments.
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Analysis of Quality Control of Brownies Home Business Products Using Statistical Quality Control
Authors: Wahyuni Selvia Anggun , Fadjryani  , Nadya Humairah Ramadhany
Published: June 2022

Brownies Home Business is one of the home-scale industries that produce brownies. This business began in 2011 and still active today. Brownies Home Business has conducted quality control over the products produced, but there are still failing products produced by the business. Even though the product failed to affect the benefits obtained because the costs incurred increased. For this reason, it is necessary to have quality control so that the products obtained experience less product failure. The analysis conducted in this study uses the Statistical Quality Control (SQC) approach. Statistical Quality Control (SQC) is a problem solving technique that used to control, analyze, and improve products so that they are expected to contribute to improving the quality of a production. Statistical Quality Control (SQC) analysis showed that the number of products examined was 2100 brownies with an average production that was damaged during fourteen days of observation of 7,71% with a total of failed products produces as many as 162 brownies. The type of damage that can occur in brownies products produced include immature defect, swift defects, and burns defects. The most common type of damage was defective immature by 56,79% with a total product of 92 brownies. From the analysis results obtained that the quality control in Brownies Home Business is well controlled.
La otra escuela. Estrategias y materiales didácticos digitales antes y después del Covid-19, un estudio de caso
Authors: Sequera Aguilar Elizabeth Josefina
Published: June 2022

Cuando se hace referencia a la otra escuela donde la tecnología podría considerarse un medio y no el fin, sabríamos pensar e imaginar la escuela digital, sin espacio físico, conectada con muchos, flexible, colaborativa de estrategias y materiales didácticos trascendentales para la transformación del aprendizaje tradicional. 

El objetivo de este estudio comparativo de casos fue analizar las estrategias y los materiales didácticos digitales utilizados por un grupo de docentes venezolanos antes y después de la llegada del Covid-19. Esta investigación cualitativa se apoyó en el análisis de contenido como metodología, para ello se aplicó una entrevista en profundidad a 36 docentes vía telefónica a raíz de la propagación de virus Covid-19.

Los hallazgos revelaron un antes y un después de la pandemia en cuanto a el uso de estrategias y materiales digitales. No obstante, la escuela no puede permanecer al margen de esta realidad a pesar de los cambios llegada la pandemia, aún falta mucho por hacer para materializar la otra escuela.
CASE REPORT OF A FIFTEEN-YEAR-OLD WITH SEVERE HAEMOPHILIA A WHO PRESENTED WITH SPONTANEOUS HAEMOTHORAX TO CHRIS-HANI-BARAGWANATH ACADEMIC HOSPITAL IN JULY 2021
Authors: Hayward Lioba , Bassinghtweighte Mairi , Zanini Andrea , Viljoen Ilana
Published: June 2022

Spontaneous massive haemothorax is a rare but severe complication seen
in children with haemophilia A. It is largely preventable with Factor
VIII. prophylactic replacement therapy, and therefore is unusual to be
seen as in the described case.
Occult Arterial Bleeding Associated With Cardiac Device Implantation
Authors: Demirtaş Abdullah , Sanhueza Eduardo , Singh Sheldon
Published: June 2022

Arterial bleeding can take a dramatic course with severe bleeding,
therefore it requires an immediate diagnosis and treatment. In this case
series, we present 2 cases of arterial injury during pacemaker
implantation.
The time-domain scattering by the elastic shell in a two-layered unbounded structure
Authors: Zhang Lei
Published: June 2022

The subject of this research is the time-domain scattering problem for a
three-dimensional layered elastic shell submerged in a two-layered fluid
separated by an unbounded rough surface. The essence of the problem is
to model the scattering interaction between the given elastic shell and
some incident wave in a two-layered medium. Using the exact transparent
boundary condition (TBC), we reformulate the unbounded scattering
problem into an equivalent initial-boundary value problem. The
well-posedness is proved for the problem by the Laplace transform and
variational method in the s-domain. Moreover, we show that the reduced
problem has a unique weak solution by the energy method. The priori
estimates with explicit dependence on the time are derived for the
acoustic pressure and the elastic displacement in the time domain.