bluuebunny/crossref_metadata_2025 huggingface dataset:
Machine Learning Algorithms for Intrusion Detection in Cybersecurity
Authors: Mane Prof. Dipali
Published: May 2023

Abstract: Computer networks and virtual machine security are very necessary in today’s time. An Intrusion Detection System (IDS) is a security mechanism designed to monitor computer networks or systems for malicious activities or unauthorized access attempts. The primary function of an IDS is to detect and respond to potential security breaches in real time. Tasks performed by an IDS are anomaly detection, Signature detection, security alert generation, etc… Various researchers are actively working on different ideas for increasing the performance of the IDS. We have used a machine-learning approach for intrusion detection. We have used SVM, Random Forests, and Decision trees for detecting intrusions.
Text Summarization and Conversion of Speech to Text
Authors: Abhale Prof. Priyanka
Published: May 2023

Abstract: This article describes the fusion of recurrent neural networks and deep learning algorithms for text summarization systems and analysis of the text learning process. Next, the text analytics learning model is summarized. In addition, applications of deep learning-based text analysis are also introduced. Language is the most important part of communication between people. Although there are many ways to express our thoughts and feelings, language is considered the most important medium of communication. Speech recognition is the process by which machines recognize different people's voices based on specific words and phrases. End-to-end deep learning techniques can be used to identify and simplify spatial representations of text data and semantic information. This study considers text analysis based on deep learning
Review of Malware and Phishing in the Current and Next Generation of the Internet
Authors: Chandel Tanmay
Published: May 2023

Abstract: The advent of Web 2.0 and Web 3.0 technologies has created new opportunities for cybercriminals to launch malware and phishing attacks. This review paper aims to provide an overview of the current state of these types of attacks in Web 2.0 and Web 3.0 environments, as well as the tools and strategies that can be used to prevent them. The paper begins by defining malware and phishing and describing the basic methods used to execute these attacks. It then delves into the specific characteristics of Web 2.0 and Web 3.0 environments that make them vulnerable to these types of attacks. For example, the ability to share information and collaborate in real time in Web 2.0 environments can create opportunities for cybercriminals to exploit trust relationships and launch phishing attacks. In Web 3.0 environments, the use of blockchain and decentralized technologies introduces new challenges for preventing malware and phishing attacks. The paper discusses the the functioning and the procedures which are followed in the event of a malware attack or phishing attack in unison with social engineering and also takes a look at a case study of a real life phishing attack in web 3.0. The paper concludes by outlining some of the key tools and strategies that can be used to prevent malware and phishing attacks in Web 2.0 and Web 3.0 environments. These include technical measures such as anti-malware software, firewalls, and spam filters, as well as user education and training to recognize and avoid phishing attacks. Overall, the paper provides a comprehensive overview of the current state of malware and phishing attacks in Web 2.0 and Web 3.0 environments, as well as the strategies and tools that can be used to prevent them. As the use of these technologies continues to grow, it is essential that individuals and organizations take steps to protect themselves against these types of cyber attacks.
Job Recommendation for Daily Paid All Workers
Authors: Mane Miss. Seema , Adak Abhang , Rathore PratapSingh , Chaudhar Manasi , Ubhe Santoshi
Published: May 2023

stract: In the last years, job recommender systems have become popular since they successfully reduce information overload by generating personalized job recommendation. Currently recommendation Systems are utilized to handle the issue of the overwhelming amount of data or the information in every domain and enables the clients to concentrate on data that is more relevant to their area of interest. One such field where recommender frameworks can play a vital role is to help workers who works on daily wages basis by recommending a job based on their skills and interest. In the current scenario, with an abundance of different industries and fields, a huge number of jobs are available for the skilled and literate professionals. It is not difficult to find suitable jobs for a person after his field has been identified but the main obstacle for achieving this goal is lack of information and awareness. The problem is that there is no such relevant recommendation system available currently so, we proposed the “Job recommendation system for daily paid workers” by analysing the skills of a particular worker and then finding appropriate jobs in his area of interest. To make this system even more robust, a wide variety of factors are taken into consideration while recommending jobs to a worker’s who work on daily wages basis
Role of IoT in Agriculture in India in Water Irrigation
Authors: Bhandari Babita , Patel Rakesh , Tiwari Akshat , Sharma Namita , Thawait Shiwangi
Published: May 2023

Abstract: The Indian agricultural sector could be drastically changed by the Internet of Things (IoT), a rapidly developing technology. IoT can be quite useful in maximizing water usage in agricultural activities. Water irrigation is one of the most important parts of agriculture. In this study, we explore the current irrigation situation in Indian agriculture, the difficulties farmers confront, and the possible advantages of implementing IoT-based irrigation system solutions. We look at the several Internet of Things (IoT) technologies and applications that may be utilized in agriculture, such as sensors, drones, and machine learning algorithms, in order tomaximize water use, cut down on waste, and boost crop yields. Finally, we propose suggestions after discussing the obstacles and prospects for the mainstream use of IoT in Indian agriculture.
ADESÃO AO TRATAMENTO ONCOLÓGICO: perscrutando sujeitos que vivenciam este processo
Authors: Miranda Maíra Aparecida Fraga , Piva Maristela
Published: May 2023

Cancer is an important public health problem, which conditions the recovery of health to the adherence to treatment demonstrated by the subjects affected by the disease. This study sought to understand which factors facilitate and hinder adherence to cancer treatment and what are the possible interventions. This is a qualitative research with documental design, in which statements of subjects undergoing cancer treatment published in social networks were collected and grouped. The methodology of data analysis was guided by Content Analysis, and from the exploration of the statements, five thematic categories were identified: the subject and his internal world; the impacts on quality of life; subject, family and health team; health system and its conditioning factors; protective resources. The results indicated that adherence to treatment is a multifactorial phenomenon, which requires a broad and empathetic look at the construction of policies and health care. It is essential that health practices recognize the subjectivity of individuals affected by cancer. And thus, understand their difficulties in adherence as part of the process of adaptation to this condition and rethink interventions that help in this process.
Repensar la relación entre el lugar y la memoria
Authors: Rodríguez Sánchez Luz Cecilia
Published: May 2023

Repensar el lugar respecto a su relación con la memoria, supone una oportunidad de indagar cómo ha sido entendido el lugar en la construcción de la memoria, a fin de reflexionar acerca de los procesos de significación que van más allá de una mera referencia geográfica, bajo el principio de la llamada espacialidad vivida. Para ello se propone hacer una revisión de tres autores David Harvey, Paul Ricoeur y Pierre Nora, esto supone una oportunidad para ampliar el discurso mediante tres visiones desde diferentes disciplinas, bajo el principio de generar una comprensión complementaria respecto al lugar y su relación con la construcción de la memoria en general y, en específico de la memoria urbana, a fin mostrar las posibilidades que tiene el lugar en la conformación de ésta, al revalorar la al lugar como un elemento primario en la construcción de la memoria, la cual adquiere múltiples posibilidades cuando se trata de la memoria urbana, pues la ciudad es y será una ventana abierta para construir y reconstruir la memoria colectiva más allá de monumentalidad.
Caracterización histórica y cultural del patrimonio minero como alternativa de desarrollo
Authors: Espinoza Aguilar Yuri Patricio , Mayorga Cárdenas Miguel Yury
Published: May 2023

La extracción minera se ha dado por muchos años específicamente en el cantón Portovelo de la provincia de El Oro en el Ecuador, dicha práctica nace en Curipamba (tierra de oro). Para realizar la caracterización histórica y cultural que ha sufrido el cantón Portovelo se emplea la metodología basada en mapas temáticos, cuyo objetivo es conocer la transición que ha tenido el sector debido a las actividades extractivas mediante la herramienta de ARGIS y en complemento con fichas adaptadas al presente trabajo, con el propósito de identificar y recuperar la infraestructura, historia y tradiciones como alternativa de desarrollo.
ilusión de la palidez
Authors: Alvarado Borgoño Miguel
Published: May 2023

En este artículo examinaremos la noción de raza, particularmente en lo referido a la raza negra, y su proyección conceptual y por lo tanto en sus connotaciones y proyecciones epistemológicas; ello en el contexto del proceso sostenido de inmigración de población haitiana a nuestro país; deseamos ser una instancia de reflexión que permita diferenciar el concepto de raza de su acepción biológica, para constituirse en una categoría social y psicocultural que, como tipo ideal, permita la comprensión de la creciente diversidad en Chile. Así, el concepto se vincula con una espiritualidad de la negritud, que deriva de una espiritualidad en la acepción que le proporciona la teología latinoamericana.
O INSTITUTO DO ESTADO DE COISAS INCONSTITUCIONAL E SUA COMPATIBILIDADE COM A ORDEM JURÍDICA BRASILEIRA BALANÇO DAS MEDIDAS CAUTELARES FIXADAS PELO STF NA ADPF 347
Authors: Maciel Bruno , Souza Taiguara
Published: May 2023

The object of this article is to research ADPF 347, analyzing the decision, in a precautionary measure determined 6 years ago, in which the Federal Supreme Court (STF) recognized the unconstitutional state of affairs (ECI) in the national penitentiary system . As the ECI constitutes a structural decision modality, an incursion will be made into the structural measures created to implement the decision handed down by the Supreme Court of the United States in the case of Brown v. Board of Education in 1954 which found racial segregation in the school system unconstitutional. As the ECI is a jurisprudential construction of the Constitutional Court of Colombia, can such an institute be successfully applied in Brazil? To this end, a brief digression will be carried out on the political, social and legal context of the country where the ECI was created. In addition, the impact of ADPF 347 on the prison system will be evaluated. Has care been taken to create a supervisory mechanism for the measures determined by the STF? Continuing, the need for the ECI to be used within a context of dialogic activism will be defended, that is, priority should be given to flexible decisions constructed in a negotiated manner between the public agencies and civil society entities involved, in order to obtain the greater legitimacy and effectiveness of structural measures.
KERANGKA YURIDIS STRATEGI PENCEGAHAN FRAUD DALAM PELAKSANAAN INVESTASI PEMERINTAH DAERAH DALAM RANGKA MEWUJUDKAN GOOD GORVENANCE DI KABUPATEN MALANG
Authors: Solehuddin Solehuddin , Risang Bagaskoro Ladito , Casmi Arrsa Ria
Published: May 2023

Penyelenggaraan Investasi Pemerintah Daerah memegang peran penting dan strategis dalam rangka mempercepat purtumbuhan perekonomian serta meningkatkan pelayanan kepada masyarakat. Kedudukan Kabupaten Malang sebagai penyelenggaraan Pemerintahan Daerah oleh ketentuan Undang-Undang Nomor 23 Tahun 2014 tentang Pemerintahan Daerah. Adapun Kewenangan yang dimiliki Pemerintah Kabupaten Malang meliputi regulasi, operasional dan supervisi.  Kerangka yuridis strategi pencegahan fraud dalam pelakasanaan investasi Pemerintah Daerah dalam rangka mewujudkan good governance di Kabupaten Malang belum di laksanakan pada praktek investasi di 4 (empat) BUMD meliputi Perumda Tirta Kanjuruhan, BPR Artha Kanjuruhan, PD Jasa Yasa, Bank Jatim. Ketiadaan analisis kelayakan, analisis portofolio dan analisis risiko berpotensi pada praktik curang/fraud dalam pelaksanaan investasi (Penyertaan Modal) Pemerintah Daerah sehingga praktik pelaksanaan inevstasi akan bertolak belakang dengan upaya Pemerintah Kabupaten Malang mewujudkan tata Kelola pemerintahan yang baik.
Critical Legal Studies: Memahami Hubungan Antara Kepentingan Bisnis, Pemerintah dan Hukum
Authors: Trianto Agus , Rosida Nina , Wijaya Endra
Published: May 2023

Kajian ini membahas mengenai pemikiran Critical Legal Studies (CLS) sebagai salah satu cabang aliran pemikiran dalam bidang hukum. Kajian mengenai CLS ini dibahas dengan pendekatan konseptual dan teoretis dengan mengungkapkan beberapa pendapat ahli hukum. Para pemikir CLS mengajukan kritik terhadap tatanan hukum yang ada, yang mereka anggap sebagai tatanan yang liberal. Dalam tatanan yang liberal, CLS memandang hukum beserta dengan entitas pemerintah dalam arti yang luas, yang membentuk dan menerapkan hukum, telah tersubordinasi oleh kepentingan aktor-aktor bisnis. Dengan demikian, hukum serta pemerintah memang akan sulit untuk benar-benar bersifat netral dan objektif.
ANALISIS HUKUM HAK MEMILIH PENYANDANG DISABILITAS MENTAL DALAM PEMILIHAN UMUM
Authors: Adhyaksa Andika
Published: May 2023

Penelitian ini bertujuan untuk menganalisis kedudukan hukum terhadap hak pilih penyandang disabilitas dalam pemilihan umum dan untuk menganalisis keabsahan hak pilih penyandang disabilitas mental dalam pemilihan. Tipe Penelitian yang digunakan adalah tipe penelitian hukum normatif, yang meletakkan hukum sebagai sistem norma. Teknik memperoleh bahan hukum dengan cara penelitian kepustakaan (Library Research) dengan mengumpulkan bahan hukum yang dilakukan dengan cara membaca, mengutip, mencatat dan memahami berbagai literatur hukum dan Perundang-Undangan. Bahan hukum yang dianalisis berupa Peraturan Perundang-Undangan dan Isu hukum yang selanjutnya diinterpretasikan dengan menggunakan cara berfikir deduktif. Hasil penelitian menunjukkan bahwa 1) Penyandang Disabilitas Mental merupakan warga negara yang diakui dan dijunjung haknya untuk dapat memilih dan dipilih dalam Pemilihan Umum sebagaimana amanat konstitusi untuk memberikan persamaan kedudukan masyarakat dalam hukum dan pemerintahan dan telah dijamin dalam Peraturan Perundang-Undangan. 2) Pemenuhan Hak penyandang disabilitas mental masih banyak penolakan dari masyarakat dan bertentangan dengan penyelenggaraan pemilihan umum yang berdasarkan atas asas langsung, umum, bebas, rahasia, jujur dan adil.
Museum specimens and occurrences of Glottidia audebarti, Discradisca strigata and other brachiopods (Brachiopoda) in the Pacific of Costa Rica
Authors: Vargas Zamora José A. , Vargas-Castillo Rita
Published: May 2023

Introduction: Lamp shells or brachiopods have a rich fossil record but only about 400 extant species. Their diversity on the Eastern Pacific is poorly known and only eight species are reported for the Pacific of Costa Rica. Objective: To list the specimens from Costa Rica and provide a distribution map along its Pacific coast. Methods: We checked collections at the University of Costa Rica (MZ-UCR) and Scripps Institution of Oceanography. Results: We found 22 records at MZ-UCR and 10 at Scripps, both include unidentified specimens, as well as Glottidia audebarti and Discradisca strigata, which are frequently collected intertidally. Conclusion: The study of Eastern Pacific living brachiopods is at an early stage; ecological studies could focus on the more easily accessed intertidal species.
Lista de revisores 2022
Authors: Research Journal UNED
Published: May 2023

Lista de revisores 2022
Fatores associados à exposição ao HIV em usuários de álcool
Authors: Fernandes Suelen Soares , Benzano Daniela , Paz Aline F. , Ornell Felipe , Kessler Felix H. P. , Schuch Jaqueline B. , Diemen Lisia Von
Published: May 2023

A prevalência de HIV é maior em Porto Alegre comparada ao restante do país. O abuso de álcool afeta o juízo crítico, sendo associado a comportamentos de risco que podem levar à contaminação pelo HIV. Objetiva-se analisar fatores associados à exposição ao HIV em alcoolistas com práticas sexuais de risco comparando com aqueles que se previnem.
An Analysis of Undergraduate EFL Students’ Perceptions of Intercultural Sensitivity
Authors: Nguyen Huyen-Thanh
Published: May 2023

Intercultural sensitivity, which is seen as an affective component of intercultural competence, is crucial to cultivating one’s favorable emotions about cultural differences experienced in intercultural communication. This qualitative study was conducted to find out how undergraduate English as a foreign language (EFL) students in Vietnam perceived intercultural sensitivity. The results showed that although the majority of students had not previously heard the phrase “intercultural sensitivity” before taking part in the survey, their intuitive understanding of the term was rather close to that of the literature. The participants were well aware of the evaluation of their intercultural sensitivity level. EFL students had different strategies for improvement of intercultural sensitivity depending on their study level and intercultural awareness. All participants, especially those who were learning a second language, believed that intercultural awareness is crucial. The study findings point to the recommendation that educators strive to further integrate intercultural sensitivity instruction and learning to improve EFL students’ capacity for intercultural communication.
Rhetorical Strategies Used by Information Technology Students in In-Class Presentations
Authors: Ellederová Eva
Published: May 2023

Rhetoric plays an important role in helping information technology (IT) professionals communicate their ideas clearly and effectively. By employing rhetorical devices when speaking about technology topics, IT professionals can present logical and convincing arguments, and demonstrate their knowledge and expertise while engaging the audience and making complex technical concepts more accessible for non-experts. This study attempts to understand how IT students construct and develop persuasive arguments by analysing their use of rhetorical strategies in a sample of persuasive presentations delivered in the course “English for IT”. Both corpus analysis and manual analysis were used to identify different types of rhetorical strategies students employed to influence their audiences’ attitudes. The results show that IT students not only created a logical appeal which might be more natural for them but also employed a wide range of rhetorical strategies and devices to establish disciplinary credibility and create a more personal connection with their audience, thus maintaining an appropriate balance of logos, ethos and pathos. The study further recommends systematic and careful rhetorical analysis of ESP (English for specific purposes) students’ spoken language across disciplines and the consequent adaption of learning materials and teaching methods to improve ESP students’ rhetoric skills.
Quantitative study on deep migration and plugging law of deformable gel particles in porous media
Authors: Zhao Wenjing , Wang Jing , Qi Zhongyang , Liu Huiqing
Published: May 2023

The breakage and deep plugging law of deformable gel particle (DGP) in
porous media are not clear. In this study, the flow experiments of DGP
were carried out, the changes of residual resistance coefficient (RRC),
DGP size and concentration along the way were measured, and the breakage
and plugging law of DGP was quantitatively characterized. The results
show that the passage after breakage is the main migration behaviors of
DGP, and DGP are reduced by half in front of the porous media. Breakage
is an important reason for the continuous decrease of concentration,
particle size and RRC. However, the DGP can plug in deep of the porous
media after breaking. The higher the injection rate or the larger the
DGP size, the faster the breakage along the injection direction, and the
worse the deep plugging ability. The empirical model can be used to
optimize the DGP parameters in oil field.
The Unique Impacts of COVID-19 on Low-Income Canadian Mother’s Mental Health Profiles: A Latent Transition Analysis
Authors: Burns Samantha , Jegatheeswaran Calpanaa , Barron Christine , Perlman Michal
Published: May 2023

There is evidence of an overall decline in maternal mental health in the
wake of the COVID-19 pandemic. However, there is also heterogeneity in
maternal responses. A latent transition analysis was conducted to
identify profiles of anxiety, depression, and stress among 289
low-income mothers. Using these identified profiles, we examined the
transitional patterns between profiles before and during COVID-19 and
the sociodemographic and familial factors related to these profiles. A
three-profile solution was identified prior to COVID-19, and a
four-profile solution during COVID-19, with some profiles exhibiting
qualitatively different defining characteristics. Latent transition
analyses found diverse patterns of mental health shifts after the onset
of COVID-19. However, mothers with better mental health prior to
COVID-19 tended to have the most stable mental health during COVID-19.
In contrast, mothers who were highly stressed prior to COVID-19 were
equally likely to improve or decline after the onset of the pandemic. In
addition, the relationships between ethnicity, parenting practices,
child temperament, and mental health were significantly related to
maternal mental health. These findings describe mothers’ experiences and
areas where policymakers and practitioners can tailor support to
low-income mothers.
The lived experiences of people with misophonia in educational, work, and everyday settings: an Interpretative Phenomenological Analysis
Authors: Robinson Oliver , Zdravkova Radostina
Published: May 2023

Background and Objectives Misophonia is a condition
characterised by the experience of negative emotional and physiological
reactions to specific sounds, such as chewing, pen tapping or sniffing
(Potgieter et al., 2019). People suffering from misophonia experience
irrational and disproportionate feelings of anger, disgust, and harm
ideation that negatively impact their lives. The current study aims to
address a gap in the literature by exploring people’s lived experience
with self-diagnosed misophonia in educational, work, and everyday
settings. Methods Five interviews were conducted with
individuals who self-diagnosed as having misophonia. Interview
transcripts were analysed using Interpretative Phenomenological
Analysis. Results The analysis revealed four superordinate
themes: ‘Phenomenology of the misophonia reaction’, ‘Susceptibility to
triggering sounds’, ‘Coping strategies when triggered’, and ‘Levels of
attention and concentration’. Misophonia was reported as having
wide-ranging effects on mental health and familial/social relationships.
Coping strategies that re-direct attention and concentration, such as
mindfulness techniques, were reported to be effective in ameliorating
aversive reactions. Conclusions The findings provide the first
phenomenological insight into misophonia through ideographical analysis
of a small number of cases. Future research and implications of the
study are discussed.
Scalable Interfacial Modification of Zn Anode for Aqueous Rechargeable Batteries with Improved Capacity and without Hydrogen Evolution
Authors: Yuan Xiangcheng , Xu qiuju , Li yiqing , Gan mi , Liu Jinzhang
Published: May 2023

The Zn anode in rechargeable aqueous Zn-ion battery (AZIBs) suffers from
hydrogen gas evolution and dendrite growth, which are critical issues
making the current AZIB technology immature. Here, these issues are
efficiently tackled by forming an amorphous
ZnSe protective layer over the Zn
foil surface through a simple chemical bath reaction process. The
anti-corrosion performance of the Zn anode in aqueous electrolyte is
greatly improved, and the Zn@ZnSe
symmetric cell exhibits notable rate performance and long cycle life of
4500 h after being tested at 1 mA cm and 1 mAh
cm. Also, the use of
Zn@ZnSe leads to a larger
Zn transference number, compared to that that using
bare Zn anode. When combined with a MnO-based cathode,
the button-type full cell using
Zn@ZnSe exhibits higher capacity and
much longer cycle life, compared to the counterpart using bare Zn anode.
It is found that the in situ formation of an amorphous ZnO nanosheet
network induced by the amorphous
ZnSe overlayer plays a key role in
improving the Zn anode performance. Pouch cells using high-mass-loading
MnO cathode and as-prepared Zn anode are made to
demonstrate the hydrogen evolution inhibition and some practical
applications.
Anthropogenic and climatic drivers of population densities in an African savanna ungulate community
Authors: Bierhoff Lukas , Bond Monica , Ozgul Arpat , Lee Derek
Published: May 2023

Many ungulate species in Africa range in habitats that vary in type and
quality over space and time, but ongoing environmental change is
substantially altering their habitats. Identifying key environmental
variables that regulate ungulate population densities can guide
management actions for effective conservation. We studied the local
population density responses of a community of sympatric ungulate
species in the Tarangire Ecosystem of northern Tanzania, to a suite of
environmental factors that vary over space and time, to quantify
population trends, determine the primary environmental correlates of
densities, and identify covariation in densities among species. We
estimated seasonal densities of five commonly detected species (impala,
dik-dik, Grant’s gazelle, eland, and waterbuck) based on 7 years of
distance-sampling data from 41 replicate surveys of 237 line transects.
We systematically analyzed the effects of spatial, seasonal, and annual
environmental covariates on variation in transect species-specific
densities across space and time. Despite large fluctuations in climatic
factors, we documented more spatial than temporal variation in four of
the five species, suggesting that spatial heterogeneity may provide some
buffer against temporal variation in the environment. Protection of
sufficient habitats and water sources should allow ungulates to respond
to a temporally changing world by moving across space. Further,
among-species covariation patterns identified two potential ungulate
guilds (impala—dik-dik—waterbuck; eland—grant’s gazelle) that
should aid in developing efficient and coordinated management actions.
Paroxetine induced hyponatremia in a 52 years old male hypertensive patient
Authors: khan Muhammad umer , Zulifqar Alisha , khetpal Raja , Raja Roomi
Published: May 2023

INTRODUCTION: Paroxetine is an antidepressant belonging to the class of
SSRI. It is used in multiple psychiatric disorders including depression,
anxiety and obsessive-compulsive disorder. Apart from being very
efficacious, it causes some adverse effects too and hyponatremia is one
of them. The association between the two is not well established, which
makes this case worth of attention. CASE PRESENTATION: A 52 years old
male hypertensive patient was brought to the ER after having an episode
of seizure. Hyponatremia due to an unknown cause was made a provisional
diagnosis. He was then referred to the psychiatric department for
further assessment, where his detailed history was taken and mental
state examination was performed. The patient was found to be suffering
from chronic depression. The patient has been taking a combination of
antipsychotics and antidepressants for this condition. Paroxetine,
Olanzapine and Quetiapine were prescribed to him by his psychiatrist 10
years back, and since then he was taking it daily. His current
medication was then immediately altered and paroxetine was replaced by
mirtazapine. DISCUSSION/ CONCLUSION: Numerous studies have been done on
the effects of SSRIs, but very few of them mentioned their association
with hyponatremia. Electrolyte imbalances are common with many
medications including antiepileptic and antidepressant drugs as well.
Although some literature has shown the link between the two, drug
induced hyponatremia remained one of the rarest adverse effect. In
summary, paroxetine is very effective in the management of depression
but its long-term use could result in an electrolyte imbalance in
hypertensive patients
A spectrophotometric trimethylamine monooxygenase assay
Authors: Ramanathan Gurunath , Maurya Shiwangi , Singh Abhishek
Published: May 2023

Trimethylamine monooxygenase ( Tmm, EC-1.14.13.148) belongs to
the family of flavin-containing monooxygenases (FMOs) that oxidize
trimethylamine into trimethylamine-N-oxide (TMAO). Conventional methods
for assaying Tmm are accurate over a narrow range of substrate/
product concentrations. Here we report a TMAO-specific enzymatic assay
for Tmm using polyallylamine hydrochloride (PAHCl)-capped MnO
nanoparticles (PAHCl@MnO ). We
achieved TMAO specificity using iodoacetonitrile to remove interfering
trimethylamine. The change in the concentration of TMAO is measured by
observing the difference in the absorbance of
3,3´,5,5´-tetramethylbenzidine (TMB) at 652 nm. The assay is tolerant to
several interfering metal ions and other compounds. This method is more
reliable and easier than currently known methods. The limit of detection
(LOD) and limit of quantitation (LOQ) are 1 µM and 10 µM, respectively,
for direct TMAO measurement.
Protection Method of Traction Power Supply System for Low and Medium Speed Maglev Traffic Based on Fault Traveling Wave Features
Authors: Yan Ningning , Wang Jian , Li Qingmin
Published: May 2023

Low and medium speed magnetic levitation traffic with short power supply
distance and complex grounding network structure, prone to power supply
rail grounding faults. However, the existing fault location methods do
not accurately locate the fault point, which in turn makes it difficult
for the protection device to act to cut off the fault. To address the
above problems, this paper builds a dynamic simulation model of the low
and medium speed magnetic levitation power supply rails to study the
distribution characteristics of the fault traveling waves after a ground
fault occurs in the power supply rails, and analyses the generation
mechanism of the traveling wave spectrum through formula calculation.
The first step is to determine whether an earth fault has occurred by
analysing the difference in current between the positive and negative
busbars. Secondly, the direction of the current difference between
stations is compared to locate the faulty section. Finally, the fault
distance is calculated from the frequency difference of the fault
voltage at the double-ended station. Through simulation, the method is
validated to be unaffected by fault location, fault transition
resistance, noise interference, and is applicable to short circuit
faults caused by lightning strikes, and the ranging error always remains
within 20m. The method has strong robustness, can effectively solve the
problem of protection misoperation and accurately locate the fault
point. It is suitable for low and medium speed magnetic levitation
transportation power supply rail ground fault.
A Rare Case of Idiopathic Thrombocytopenic Purpura with Unusual Clinical Manifestations
Authors: Patel Tirath
Published: May 2023

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune condition
marked by isolated thrombocytopenia, which makes people more likely to
hemorrhage. We provide a case of a 45-year-old female patient with ITP
who displayed unusual clinical symptoms, emphasizing the diagnostic
difficulties and treatment options in such circumstances.
Epidemiological landscape of Batrachochytrium dendrobatidis and its impact on amphibian diversity at global scale
Authors: Basanta M. Delia , Velasco Julián , González-Salazar Constantino
Published: May 2023

Chytridiomycosis caused by the fungal pathogen Batrachochytrium
dendrobatidis (Bd) is a major driver of amphibian decline worldwide. The
global presence of Bd is driven by a synergy of factors, such as
climate, species life history, and amphibian host susceptibility. Here,
using a Bayesian data-mining approach, we modelled the epidemiological
landscape of Bd to evaluate how the infection varies across several
spatial, ecological, and phylogenetic scales. We compiled global
information on Bd occurrence, climate, species ranges, and phylogenetic
diversity to infer the potential distribution and prevalence of Bd. By
calculating the degree of co-distribution between Bd and our set of
environmental and biological variables (e.g., climate and species), we
identified which factors could potentially be related to Bd presence and
prevalence using a geographic correlation metric, epsilon (ε). We fitted
five ecological models based on: i) amphibian species identity, ii)
phylogenetic species variability values for a given species assemblage,
iii) temperature, iv) precipitation, and v) all variables together. Our
results extend the findings of previous studies by identifying the
epidemiological landscape features of the presence of Bd. This
ecological modelling framework allowed us to generate explicit spatial
predictions for Bd prevalence at global scale and a ranked list of
species with high/low probability of Bd presence. Our geographic model
was able to identify areas with high potential for Bd prevalence as
potential risk areas and areas with low potential Bd prevalence as
potential refuges (free Bd). At the amphibian assemblage level, we found
a non-relationship with amphibian phylogenetic signals, but a
significantly negative correlation between observed species richness and
Bd prevalence indicated a potential dilution effect at the landscape
scale. Our model may identify potential susceptible species and areas at
risk of Bd presence which could be used to prioritize regions for
amphibian conservation efforts and assess species and assemblage risk
Advances in Biosynthesis of Peptide Drugs: Technology and Industrialization
Authors: Wang Jing , Chen Long , Qin Song , Xie Mingyuan , Luo Shizhong , Li Wenjun
Published: May 2023

Peptide drugs are developed from endogenous or synthetic peptides with
specific biological activities. They have advantages of strong target
specificity, high efficacy and low toxicity, thus showing great promise
in the treatment of many diseases such as cancer, infections and
diabetes. Although an increasing number of peptide drugs have entered
market in recent years, the preparation of peptide drug substances is
yet a bottleneck problem for their industrial production. Comparing to
the chemical synthesis method, peptide biosynthesis has advantages of
simple synthesis, low cost, and low contamination. Therefore, the
biosynthesis technology of peptide drugs has been widely used for
manufacturing. Herein, we reviewed the development of peptide drugs and
recent advances in peptide biosynthesis technology, in order to shed a
light to the prospect of industrial production of peptide drugs based on
biosynthesis technology.
CANADIAN MUSTARD: VARIETIES, COMPOSITION, PHENOLICS, PROCESSING, AND APPLICATIONS: A REVIEW
Authors: Nguyen Thu , Nandasiri Ruchira , Fadairo Olamide , Eskin Michael
Published: May 2023

Mustard seeds have been used since ancient times contributing great
economic value to global agriculture. Canada, one of the world’s top
producers, grows three main mustard varieties, white /yellow, (Brassica
hirta/ Sinapis alba), black (Brassica nigra) and Oriental (Brassica
juncea). Besides their high protein and lipid content, mustard varieties
are a rich source of phenolic compounds. This review will cover mustard
seed components including lipids, glucosinolates, and sinapates. The
latter are the main phenolic compounds in mustard and include sinapine,
sinapic acid and its conversion to canolol. The important bioactivities
associated with mustard phenolics, has led to efforts to improve the
methods for their extraction. The use of green technology is crucial for
producing these phenolics while minimizing any detrimental effects to
the environment. The important antioxidant and anticancer activities of
these phenolics will also be reviewed.
Apportionment and Inventory Optimization of Agriculture and Energy Sector Methane Emissions using Multi-month Trace Gas Measurements in Northern Colorado
Authors: Mead Griffin J , Herman Daniel I , Giorgetta Fabrizio R , Malarich Nathan A , Baumann Esther , Washburn Brian R , Newbury Nathan R , Coddington Ian , Cossel Kevin C
Published: May 2023

Quantifying sector-resolved methane fluxes in complex emissions
environments is challenging yet necessary for inventory validations.  We
separate energy and agriculture sector methane using a dynamic linear
model of methane, ethane, and ammonia mixing ratios measured at a
Northern Colorado site from November 2021 to January 2022. Combining
observations with spatially resolved inventories and inverse methods,
energy and agriculture methane fluxes are constrained across a
~850 km area. Optimized energy sector
fluxes were 22% lower than the inventory despite a
~360% increase in regional energy production since the
inventory was constructed, suggesting a regional decline in emissions
factors. In contrast, optimized agriculture fluxes were 3× larger than
the inventory; we demonstrate this discrepancy is consistent with the
spatial distribution of agricultural sources. These results highlight
the utility of sector-apportioned methane observations for multi-sector
inventory optimization in complex environments, which may prove valuable
for national and global quantification of sector-resolved methane
fluxes.
Impact of Job Security on Turnover Intention Mediated by Job Satisfaction in the Context of Covid-19 in Pakistan
Authors: Atiq Nazia , Usmani Sania
Published: May 2023

Retaining intellectual capital and understanding the reasons behind Turnover intentions s are the most crucial tasks for any industry, especially in the era where organizations have the most diverse workforce in terms of generation. A high turnover carries detrimental effects for any sector. The education industry gets affected more adversely due to this factor. The primary purpose of this study is to verify the effects of lack of Job Security on the Turnover Intention with the mediation effects of job satisfaction, particularly in a covid context. Generation Y and Z were compared to understand how they both reacted to the lack of Job Security in the private education sector. Results showed that Job Security elevates Job Satisfaction and reduces intention of turnover in Gen Y. While in the case of Gen Z, the negative relationship between Job Security and turnover is stronger but Job Satisfaction will not decrease Turnover Intention  rather it increases. This is quite interesting and provides a vast area for further research in this regard. These findings offer implications for creating an environment where a diverse workforce senses and achieves high Job Satisfaction along with security to retain them, especially for Gen Y. while for Gen Z there should be some challenging tasks to keep them enthusiastic and passionate about their work.
Examining the Mediating Effect of Online Engagement and Online Reviews: The Influence of Influencer Credibility on Consumer Purchase Intentions
Authors: Zaman Syed Ahsan Ali , Anwar Adnan , Haque Irfan Ul
Published: May 2023

Companies look up to influencers because they are seen as thought leaders who mediate between the company and its followers. This results in their taking on the role of brand ambassadors or spokespersons. They play a significant role in helping businesses develop what they call a "digital relationship" with their clientele by supplementing and amplifying more traditional forms of marketing. They see digital connection as crucial in the current business climate. This study examined the effects of influencer credibility, customer review, and customer interaction on consumers' intent to buy after seeing an endorsement from an influencer, with an emphasis on Purchase intention. The study's findings indicate that customer involvement is the most important factor in determining whether a consumer will follow through on a purchase intent prompted by an influencer. The credibility of influencers had a notably large impact on consumer engagement; however, trustworthiness was also a factor. Online shoppers place a high value on accessibility to information. Because they both include customers sharing their experience and appraisal of a product or service with other potential purchasers, customer reviews and influencer endorsements can be considered customer reviews. This research reveals that consumer reviews have little impact on consumers' propensity to make a purchase. Influencer endorsement, but not customer reviews, affects desire to buy premium goods. However, the role of customer reviews as a moderator between trustworthiness and desire to buy was not established in this research.
Care Management Processes Important for High Quality Diabetes Care
Authors: A. Peterson Kevin , S. Carlin Caroline , I. Solberg Leif , Normington James , F. Lock Eric
Published: May 2023

  

Objective: Identify the improvement in diabetes performance measures and population-based clinical outcomes resulting from changes in care management processes (CMP) in primary care practices over three years. 

Research design and methods: Repeated cross-sectional study tracking clinical performance measures for all diabetes patients seen in a cohort of 330 primary care practices in 2017 and 2019. Unit of analysis was patient-year with practice-level CMP exposures. Causal inference is based on dynamic changes in individual CMPs between years by practice. We used Bayesian methods to simultaneously estimate a five-outcome model: A1c, systolic and diastolic blood pressure, guideline-based statin use, and Optimal Diabetes Care (ODC). We control for unobserved time-invariant practice characteristics and secular change. We modeled correlation of errors across outcomes. Statistical significance was identified using 99% Bayesian credible intervals (analogous to p<0.01). 

Results: Implementation of 18 of 62 CMPs were associated with statistically significant improvements in patient outcomes. Together, these resulted in 12.1 percent more patients meeting ODC performance measures. Different CMPs affected different outcomes. Three CMPs accounted for 5.7 of 12.1% total ODC improvement, 68% of A1c decrease, 21% of SBP reduction, and 55% of statin use increase: 1) systems for identifying and reminding patients due for testing, 2) after-visit follow-up by a non-clinician, and 3) guideline-based clinician reminders for preventive services during a clinic visit.

Conclusions:  Effective quality improvement in primary care focuses on practice redesign that clearly improves diabetes outcomes. Tailoring CMP adoption in primary care provides effective improvement in ODC performance through focused changes in diabetes outcomes. 
Estrategias de educación farmacéutica mediada por las TIC´s relacionadas con el uso adecuado de los medicamentos antihipertensivos que mejoren el control de la enfermedad
Authors: Larrea Galeano Johnny , Arrieta Rafael Arturo , Gomez Yisely Marcela , Rios Sossa Ramiro
Published: May 2023

La hipertensión es el asesino silencioso que pone a las personas en riesgo de sufrir efectos adversos para la salud y complicaciones graves que ponen en peligro la vida de una persona. La no adherencia al tratamiento recomendado para la hipertensión aumenta la probabilidad de fracaso terapéutico para lo cual la presente revisión intenta mostrar cómo a nivel local e internacional se le da el manejo a la terapia antihipertensiva desde un enfoque educativo con el apoyo del farmacéutico todo en torno al favorecimiento de la adherencia a la terapia mediada por la tics.El uso racional de los medicamentos antihipertensivos se debe basar en la información cientifica disponibleacerca de su eficacia, seguridad, comodidad de administración y coste. Así mismo en un componente educativo que incluya medidas no farmacológicas, un personal farmacéutico idóneo y que según su alcance legal abarque información complementaria a la terapia para que el paciente tenga bases de su uso racional y adecuado basado en el uso de herramientas tecnológicas.
Shortening of primary cilia length is associated with urine concentration in the kidneys
Authors: Kong Min Jung , Han Sang Jun , Seu Sung Young , Han Ki-Hwan , Lipschutz Joshua H. , Park Kwon Moo
Published: May 2023

Background: The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions. In kidneys, the primary cilia protrude into the tubular lumen and are directly exposed to pro-urine flow and components. However, their effects on urine concentration remain to be defined. Here, we investigated the association between primary cilia and urine concentration. Methods: Mice either had free access to water (normal water intake, NWI) or were not allowed access to water (water deprivation, WD). Some mice received tubastatin, an inhibitor of histone deacetylase 6 (HDAC6), which regulates the acetylation of α-tubulin, a core protein of microtubules. Results: WD decreased urine output and increased urine osmolality, concomitant with apical plasma membrane localization of aquaporin 2 (AQP2) in the kidney. After WD, compared with after NWI, the lengths of primary cilia in renal tubular epithelial cells were shortened and HDAC6 activity decreased. WD induced deacetylation of α-tubulin without altering α-tubulin levels in the kidney. Tubastatin prevented the shortening of cilia through increasing HDAC6 activity and consequently increasing acetylated α-tubulin expression. Furthermore, tubastatin prevented the WD-induced reduction of urine output, urine osmolality increase, and apical plasma membrane localization of AQP2. Conclusions: WD shortens primary cilia length through HDAC6 activation and α-tubulin deacetylation, while HDAC6 inhibition blocks the WD-induced changes in cilia length and urine output. This suggests that cilia length alterations are involved, at least in part, in the regulation of body water balance and urine concentration.
Use and Abuse of the Term "Psychosocial" in the Field of Social Intervention
Authors: Blanco Amalio
Published: May 2023

Applied to theory, research, and intervention, the term “psychosocial” is defined as an approach characterized by the relationships of interdependence and mutual influence between the various levels of reality in which daily life takes place. This idea began to take its first steps with the events that gave rise to the social sciences, psychology among them. Applied to social intervention, the psychosocial perspective is based on a simple premise: psychology is legitimized as an instrument to serve human well-being, both in its personal and collective dimension. It recognizes the constructed nature of reality and the social order, with the purpose of trying to change it when it leaves psychological damage and social destruction in its wake, using the social scenarios (community, group) as the agent and objective of change.