bluuebunny/crossref_metadata_2025 huggingface dataset:
SE NÃO MUDAR ESTÁ FRITZ: UM CASO SOBRE O MODELO DE EQUILÍBRIO PONTUADO
Authors: Raasch Michele , Silveira-Martins Elvis , Vasconcelos Jaqueline Chagas
Published: February 2022

O objetivo do caso para ensino é apresentar as mudanças e adaptações estratégicas realizadas em uma empresa familiar, e seus 31 anos de história (1987-2018), criada e gerenciada por mulheres. O caso é baseado em dados reais, coletados através de entrevistassemiestruturadas, análise de conteúdo. A identificação dos personagens e do estabelecimento são fictícios, para manter o sigilo do caso, já os dados e as datas são reais. A análise é baseada no modelo de equilíbrio pontuado de Tushman e Romanelli (1985). O caso para ensino foi desenvolvido para ser utilizado e disciplinas da área de estratégia, em cursos de graduação e pós-graduação. Ao longo de sua trajetória foi possível identificar os pontos de evolução, as adaptações planejadas e realizadas pelas gestoras da empresa, assim como as mudanças necessárias para sua manutenção e equilíbrio, entre períodos de inércia ao longo do tempo, até o sucesso dos dias atuais.
ADAPTABILIDADE DE CARREIRA: PRODUÇÃO CIENTÍFICA DOS ÚLTIMOS 10 ANOS
Authors: Coradini Juciéle Fátima , Lopes Luis Felipe Dias , Fabricio Adriane , Pimentel Lima Mauren , Krüger Cristiane
Published: February 2022

Objetivo: Avaliar a produção científica sobre adaptabilidade de carreira dos últimos 10 anos, no período de 2010-2019.
Método / Abordagem: Realizou-se uma revisão bibliométrica da literatura nos bancos de dados Web of Science e Scopus, entre os meses de janeiro a fevereiro de 2020, resultando, respectivamente, na seleção de 390 e 417 publicações. As publicações foram analisadas em função do ano, área, autor, fonte, país, tema e hot topics.
Principais resultados: Verificou-se que em ambas as bases pesquisadas há concentração de publicações quanto ao tema no ano de 2019, nos Estados Unidos da América, sendo os hot topics Desenvolvimento da Carreira e Empregabilidade, principalmente na área de Psicologia.
Originalidade / Relevância: O uso da bibliometria vem a ser uma ferramenta de busca e disseminação do conhecimento científico, possibilitando aos pesquisadores uma análise quantitativa e prognóstica das publicações realizadas em determinadas áreas científicas.
Palavras-chave: Carreira. Adaptabilidade. Bibliometria.
ALÉM DOS LIMITES DO VAREJO FÍSICO: AS DIFICULDADES DAS LOJAS FÍSICAS AO IMPLEMENTAREM UM E-COMMERCE
Authors: Carminatti Samuel , Zanin Bagatini Francine , Rech Lais , Araujo Pacheco Natalia
Published: February 2022

Objetivo: O presente estudo visa identificar as principais dificuldades enfrentadas pelos proprietários de lojas físicas ao implementarem uma plataforma e-commerce.
Método / abordagem: Desenvolveu-se uma pesquisa qualitativa de cunho exploratório por meio de entrevistas com dez proprietários de lojas físicas, os quais possuem uma plataforma e-commerce em funcionamento e atuam em diversos segmentos de negócio.
Principais resultados: Entre as dificuldades enfrentadas, observa-se maior carga de trabalho, a falta de profissionais qualificados para executar a operação, dificuldade de contratação e confiança nos serviços das agências digitais, dificuldade com a produção de conteúdo para os produtos divulgados no e-commerce e dificuldade de integração do estoque da loja física e da loja online.
Contribuições metodológicas / sociais / gerenciais: Os gestores brasileiros precisam estar atentos ao planejarem e implementarem um novo canal de vendas como um e-commerce. A gestão de uma loja online demanda conhecimento, planejamento, organização e integração entre as operações realizadas na loja física e na loja online.
Originalidade / relevância: A presente pesquisa possibilitou compreender as dificuldades de implementação de uma plataforma e-commerce no contexto de empresas brasileiras já consolidadas no varejo físico. Com o intuito de mitigar as dificuldades, foi possível mapear os pontos de atenção que devem ser previstos pelos gestores brasileiros ao iniciarem a implementação de um e-commerce.
Penyalahgunaan Bantuan PKH: Motif dan Dampak (Studi Kasus di Gampong Bluka Teubai Kecamatan Dewantara Kabupaten Aceh Utara).
Authors: Zulkifli  , Suadi  , Alwi
Published: January 2022

PKH has provided benefits for recipients, but its implementation in various regions does not always run well. From the beneficiary's perspective, the problem often occurs is the misuse of the assistance provided. This article briefly describes the impact and motives for the misuse of PKH assistance by beneficiary families in Gampong Bluka Teubai, North Aceh. The research method used is qualitative with a descriptive approach. Data collection techniques used are observation, interviews, and the study of relevant documents. This study found that most KPM informants used aid funds that were not following their designation. The motive for this misuse is the weak economic condition of the KPM and the assumption that the aid funds are fully proprietary so that they can be used as needed. The misuse of these aids indirectly affects the education and health aspects of KPM so that there are still KPMs who drop out of school are malnourished and stunted.

Abstrak

PKH telah memberikan manfaat bagi penerima, namun pada implementasinya di berbagai daerah, program ini tidak selalu berjalan dengan baik. Dari sisi penerima manfaat, masalah yang sering terjadi adalah penyalahgunaan bantuan yang diberikan. Artikel ini secara singkat ingin mendeskripsikan tentang dampak dan motif penyalahgunaan bantuan PKH oleh keluarga penerima manfaat di Gampong Bluka Teubai Aceh Utara. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan deskriptif.  Teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan studi dokumen yang relevan. Penelitian ini menemukan bahwa dari mayoritas informan KPM menggunakan dana bantuan masih belum sesuai dengan peruntukannya. Motif penyalahgunaan tersebut adalah lemahnya kondisi ekonomi KPM dan anggapan bahwa dana bantuan tersebut merupakan hak milik seutuhnya sehingga dapat digunakan sesuai kebutuhan. Penyalahgunaan bantun tersebut secara tidak langsung berpengaruh pada aspek pendidikan dan kesehatan KPM sehingga masih ditemui KPM yang putus sekolah, kurang gizi dan stunting.
Orta Ege Denizi’nde Yüzer Ağ Kafes Sistemlerinde Yerleşen Makro alg ve Makro omurgasız Türler Üzerine Bir Ön Araştırma
Authors: Ulaş Ali , Serdar Serpil , Yıldırım Şükrü , Göktürk Didem
Published: February 2022

Ocak-2015 ile Şubat 2018 tarihleri arasında Orta Ege Denizi, İzmir Körfezi güneybatısındaki Balıklıova kıyısında yer alan ağ kafes ünitelerinde yürütülen bu çalışmada, ağ kafes ünitelerinin yüzdürücü kafes, ağ ve halatlar gibi farklı bölümlerine tutunmuş makroalg ve makroomurgasızların oluşturduğu makrofouling organizmaların tanımlanması ve yoğunluklarının belirlenmesi amaçlanmıştır. Örneklemeler serbest dalış ve tüplü dalışlar ile gerçekleştirilmiştir. Çalışma sonunda 9’u Mollusca, 4’ü Arthropoda ve 2’si Echinodermata filumlarına ait olan toplam 15 adet makroomurgasız ile Chlorophyta ve Rhodophyta filumlarına ait 6 adet alg türü tespit edilmiştir. Mytilus galloprovincialis ve Balanus sp. en yoğun rastlanan canlılar olarak belirlenmiş olup Ulothrix, Ulva, Ceramium genuslarına ait türlerin de derinliğe bağlı değişerek dağılım gösterdikleri tespit edilmiştir. Deniz ekosisteminde yapay habitatlar olarak düşünülebilecek bu tip ünitelerin makrofouling açısından farklı türlere yaşam alanı oluşturduğu gözlenmiştir.
Ammothella longioculata (Arthropoda, Pycnogonida): A Sea Spider New For the Mediterranean Coast of Turkey
Authors: Koçak Cengiz
Published: February 2022

Sampling studies on the Turkish Mediterranean coast revealed the presence of a species of Pycnogonida belonging to the genus Ammothella. This species is identified as A. longioculata (Faraggiana, 1940). This is herein reported for the first time from the Fethiye Bay and Mediterranean coast of Turkey. Therefore, the record further extends the known distribution of A. longioculata from the Aegean Sea to the Mediterranean coast of Turkey. A distribution map of the species in the Mediterranean Sea is provided, together with photographs of the species. This study is the only scientific report to date of the pycnogonids of the Fethiye Bay in Turkey.
Analisis Besarnya Kredit Bermasalah Selama Masa Pandemi Covid-19 pada Perusahaan Financial Technology (FINTECH)
Authors: Munandar Aris , Alwi Alwi , Nurhayati Nurhayati , Herman Herman
Published: February 2022

This study aims to determine and analyze the amount of non-performing loans in Financial Technology (FINTECH) companies during the covid-19 pandemic. The research sample consisted of 12 samples from January 2020 - December 2021 with the purposive random sampling method. Data collection is done through the official website of the financial services authority and the type of data taken is secondary data. The results show that non-performing loans in Financial Technology (FINTECH) companies have an average Non-Performing Loan (NPL) value of 6.08%, which is greater than 5% of the maximum limit set. Where these conditions indicate that non-performing loans in Financial Technology (FINTECH) companies are problematic or unhealthy. The increase in non-performing loans began to increase in April 2020 after the COVID-19 outbreak began in Indonesia.
TIPOLOGI ARSITEKTUR KOLONIAL DI INDONESIA
Authors: Tamimi Nadhil , Fatimah Indung Sitti , Hadi Akhmad Arifin
Published: February 2022

Salah satu periode yang memiliki pengaruh terhadap perkembangan pembangunan di Indonesia adalah periode kolonial. Terdapat berbagai macam bentuk peninggalan bersejarah berasal dari periode tersebut, salah satunya ialah langgam atau gaya arsitektur kolonial. Bangunan yang memiliki karakter arsitektur kolonial dapat dikategorikan sebagai bangunan yang penting untuk dilestarikan karena memiliki nilai sejarah yang tinggi. Kajian yang dilakukan membahas tipologi dan pelestarian arsitektur kolonial yang berada di Indonesia. Metode yang digunakan pada kajian ini adalah studi pustaka atau literatur dengan  tujuan untuk menjelaskan arsitektur kolonial di Indonesia dan dapat bermanfaat sebagai dasar kategorisasi bangunan kolonial. Dari kajian ini dapat disimpulkan arsitektur kolonial merupakan salah satu gaya arsitektur yang ada di Indonesia sejak masa penjajahan Belanda dimana gaya, karakter, dan ciri arsitektur kolonial dipengaruhi oleh perpaduan antara budaya Belanda dan budaya Indonesia serta memiliki dua metode konservasi yaitu teknik konservasi bersifat fisik (preservasi, restorasi, dan rekonstruksi) dan non fisik. One period that has big influence on the development in Indonesia is the colonial period. There are various forms of historical relics from this period, one of which is the style of colonial architecture. Buildings that have colonial architectural character can be categorized as important buildings to be preserved because they have high historical value. The study was conducted to discuss typology and preservation of colonial architecture in Indonesia. Literature study is used in this study with the aim of explaining colonial architecture in Indonesia and can be useful as a basis for the categorization of colonial buildings. From this study it can be concluded that colonial architecture is one of the architectural styles that existed in Indonesia since the Dutch Colonial period where the style, character, and features of colonial architecture were influenced by a combination of Dutch and Indonesian culture, it also had two conservation methods, namely physical conservation techniques (preservation , restoration and reconstruction) and non-physical.
Analisis Konsep Green Roof Dan Permodelan Desain Sederhana
Authors: Rahayu Yuhana
Published: February 2022

Pembangunan secara terus-menerus di Indonesia menyebabkan Indonesia kekurangan lahan untuk Ruang Terbuka Hijau di daerah perkotaan. Hal ini memicu para kontraktor atau pun perancang desain bangunan memikirkan berbagai cara untuk mengatasi hal tersebut. Konsep green roof hadir untuk mengatasi permasalahan tersebut. Green roof merupakan konstruksi bangunan dimana terdapat media tanam dan vegetasi pada atap. Artikel ini bertujuan untuk menganalisis keefektifan pengaplikasian konstruksi green roof dan mengolah desain permodelan yang memungkinkan untuk diterapkan di Indonesia yang merupakan kawasan yang dilalui garis khatulistiwa. Metode penulisan artikel ini adalah dengan menganalisis hasil pengaplikasian green roof di Indonesia maupun luar negeri, kemudian dilakukan wawancara dengan kontraktor bangunan. Hasil dari penelitian ini yakni green roof efektif dan memiliki banyak manfaat sehingga green roof dapat menjadi jawaban bagi permasalahan lingkungan baik itu di Indonesia maupun di luar Indonesia serta mampu mereduksi suhu termal di Indonesia yang merupakan negara yang dilalui garis khatulistiwa.  Continuous development in Indonesia causes Indonesia to lack land for green open spaces in urban areas. This triggers the contractors or building design designers to think of various ways to overcome this. The green roof concept is here to overcome these problems. Green roof is a building construction where there is a planting medium and vegetation on the roof. This article aims to analyze the effectiveness of the application of green roof construction and to develop a possible modeling design in Indonesia, which is an area traversed by the equator. The method of writing this article is by analyzing the results of the application of green roofs in Indonesia and abroad, then conducting interviews with building contractors. The results of this study are that green roofs are effective and have many benefits so that green roofs can be the answer to environmental problems both in Indonesia and outside Indonesia and are able to reduce thermal temperatures in Indonesia, which is a country passed by the equator.
Existence and stability of stationary solutions to the compressible quantum model
Authors: Xi Xiaoyu
Published: January 2022

In this paper, the compressible quantum model with the given mass source
and the external force of general form in three-dimensional whole space
is considered. Based on the weighted $L^2$ method and
$L^\infty$ estimates, the existence and uniqueness
of stationary solutions can be obtained by the contraction mapping
principle. By using a general energy method, the nonlinear stability of
stationary solutions is studied, and the time decay rates of the
solutions are established when the initial perturbation belongs to
$\dot{H}^{-s}$ with $0 \leq s
< \f32$.
A mathematical model to assess COVID-19 vaccination in Thailand
Authors: Photphanloet Chadaphim , Shuaib Sherif , Ritraksa Siriprapa , Riyapan Pakwan , Intarasit Arthit
Published: January 2022

In this article, a COVID-19 transmission mathematical model
incorporating vaccination and non-pharmaceutical interventions was
formulated and theoretically analysed. Here, the COVID-19 free and
endemic equilibrium points, vaccine reproduction number were computed.
The derived vaccination reproduction number largely depends on vaccine
efficacy for disease eradication to occur. Infection risk is
significantly reduced whenever the vaccine intake is greater than one
dosage. The simulation results indicate that the administered COVID-19
vaccines and non-pharmaceutical interventions have been effective for
the current variants, additional efforts such as a third vaccine booster
shot should be considered and implemented to greatly mitigate the risk
of the emerging variants of the COVID-19 pandemic.
Need of preventive photocoagulation for retinal arterial macroaneurysm
Authors: Nagasato Daisuke , Iwawaki Takuji , Tabuchi Hitoshi
Published: January 2022

Retinal arterial macroaneurysm shows rapid vision loss when rupture
occurs; therefore, preventive photocoagulation should be considered, if
necessary.
Holistic Analytical Characterization and Risk Assessment of Residual Host Cell Protein Impurities in an Active Pharmaceutical Ingredient (API) Synthesized by Biocatalysts
Authors: Wang Fengqiang , LI Xuanwen , Swanson Michael , Guetschow Erik , Winston Matthew , Smith Joseph P. , Hoyt Erik , Liu Zhijian , Richardson Douglas , Bu Xiaodong , Jawa Vibha , Variankaval Narayan
Published: January 2022

Host cell proteins (HCPs) are a significant class of process-related
impurities commonly associated with the manufacturing of
biopharmaceuticals. However, due to the increased use of crude enzymes
as biocatalysts for modern organic synthesis, HCPs can also be
introduced as a new class of impurities in chemical drugs. In both
cases, residual HCPs need to be adequately removed to ensure product
purity, quality, and patient safety. Although a lot of attentions have
been focused on defining a universally acceptable limit for such
impurities, the risks associated with residual HCPs on product quality,
safety, and efficacy often need to be determined on a case-by-case basis
taken into consideration of residual HCP profile in the product, the
dose, dosage form, and administration route etc. Here we describe the
unique challenges for residual HCP control presented by the biocatalytic
synthesis of a Merck investigational stimulator of interferon genes
protein (STING) agonist, MK-1454, which is a cyclic dinucleotide
synthesized using E. coli cell lysate overexpressing cyclic
GMP-AMP synthase (cGAS) as a biocatalyst. In this study, a holistic
characterization of residual protein impurities using a variety of
analytical tools, together with in silico immunogenicity prediction of
identified proteins, facilitated risk assessment and guided process
development to achieve adequate removal of residual protein impurities
in MK-1454 API.
Study on energy and water balance of pepper field in arid areas
Authors: Zhang Qingtao , Wang Zhiqiang , Ke Zijun , Wu Xinyu , Wang Bei , Qiu Guo Yu
Published: February 2022

The middle Heihe River Basin (MHRB) in arid areas in China faces the
challenge of sustainability, but frequent over-irrigation deteriorated
the situation. The water balance and energy budget have not been widely
used for the quantifying evaluation of over-irrigation. Although some
studies have measured the energy budget and water balance in cropland,
the energy and water balance in pepper fields is still unclear. An
experiment was conducted using an eddy covariance system, SmartView
fluke and other measurements in MHRB. The leaf area index (LAI) for
pepper increased in the first two months, then decreased thereafter.
After Aug. 4, the daily evapotranspiration (ET) decreased during the
maturation stage. The soil moisture was higher than the field capacity
frequently, indicating that over-irrigation had occurred. Soil water
content was relatively high at 100 cm depth, causing high percolation.
The water inputs were 1.5 times ET, and the deep percolations accounted
for 74% of the total irrigation inputs. Irrigation water could be
conserved 301 mm, in case that percolation was avoided. Therefore, the
irrigation amount (per time and total) should be reduced to achieve high
water use efficiency (WUE). The latent heat flux (LE) consumed 80% of
the net radiation (Rn). In July, the LE/Rn was the highest among all
months, whereas H/Rn was the lowest due to the highest value of LAI in
July. The net radiation had a significant positive linear correlation
with the latent heat flux because of the high water supply. Our study
showed that there was considerable room for water conservation in MHRB.
Keywords: Sensible heat flux; Soil water content; Evapotranspiration;
Latent heat flux; Leaf area index
Activation of S1PR2 upregulates tumoral DPD by promoting the interaction of TWIST1 with the JMJD3-RNA Pol II complex bound to the DPYD promoter
Authors: Guo Zhi-Kun , Zhang Ying-Zhi , Zhang Yu-Hang , Luo Dong-Dong , Wan Sheng-Biao , Qu Xianjun , cui shuxiang
Published: February 2022

Background and Purpose: Dihydropyrimidine dehydrogenase (DPD) is a major
determinant of 5-FU resistance in cancers. DPD catalyzes 5-FU into FBAL
(α-fluoro-β-alanine) to lower intracellular 5-FU level. We aimed to
investigate mechanism and clinical significance of FBAL-stimulated
sphingosine 1-phosphate receptor 2 (S1PR2) in upregulation of DPD in
colonic cancer. Experimental Approach: Cancer cells transfected or
silenced S1PR2 were exposed to FBAL for analyzed S1PR2 and DPD levels.
Luciferase reporter assay analyzed S1PR2-activated TWIST1 binding to
DPYD promoter. Co-IP assay analyzed TWIST1 interaction with JMJD3-RNA
Pol II complex binding to DPYD promoter. HT-29sh-S1PR2 or SW480TgS1PR2
cells xenografted nude mice were used to evaluate clinical significance
of S1PR2-upregulated tumoral DPD. Key Results: Activation of S1PR2
upregulated DPD in colonic cancer cells and human fresh cancer
specimens. FBAL was first time identified as an etiological stimulator
of S1PR2 activation. The FBAL-stimulated S1PR2 increased TWIST1 binding
to DPYD promoter and interacting with JMJD3-RNA Pol II complex,
enhancing H3K27me3-enriched DPYD transcription elongation. Transfection
of S1PR2 in SW480TgS1PR2 xenograft contributed 5-FU resistance by
45.14%, and silence of S1PR2 improved 5-FU sensitivity by 62.12% in
HT-29sh-S1PR2 xenograft. S1PR2 inhibitor JTE013 prevented the
FBAL-stimulated S1PR2’s effects in upregulating DPD. Cancer cells with
high S1PR2 are more resistant to 5-FU, strongly suggesting clinical
significance that combination use of S1PR2 inhibitors may be the
appropriate 5-FU-based regimens of colonic cancers. Conclusions and
Implications: The FBAL-stimulated S1PR2 increased TWIST1 binding to DPYD
promoter and interacting with JMJD3-RNA Pol II, enhancing the
H3K27me3-enriched DPYD transcription elongation.
A Review of Common Tools and Techniques for Reconnaissance Attacks.. Proceedings of the
Authors:   Department of Computer & Information Sciences College of Science & Tech. Covenant University Ota, Ogun State, Nigeria, Isaac Gabriel Odun-Ayo
Published: January 2022

Background: A reconnaissance helps the attacker gain valuable information on the target to help the attacker select the best tools that would make the attack successful. Aim: This study aims to review tools for reconnaissance attacks which will be beneficial to professional ethical hackers and also enlighten organizations and the general public of the potential harm of successful reconnaissance attacks. Methodology: The databases – Springer, Elsevier, Wiley, IEEE, ACM, ArXiv, and Google Scholar were explored. A quantitative evaluation was conducted on 19 selected articles. Result: 95.2% of the reconnaissance tools allowed experts to gather information by use of the command line. While 4.8% of the tools do not provide a commandline interface. 61.9% of the tools are network-based – can be used to gather data about the target’s network infrastructure. Conclusion: The best-fit tool is massively dependent on the attacker or penetration tester. Therefore, a tool should be selected based on the user’s preference and the attack style. Keywords: Reconnaissance, cyber-attack, cybersecurity,social engineering, techniques.
Challenges of Autonomy on Effective Local Government in Nigeria
Authors:   Dept of General Studies Lagos State Polytechnic, Ikorodu Lagos State, Nigeria, Aderogba A.
Published: January 2022

The focus of this study is to examine the relationship between autonomy and effectiveness of local government in Nigeria. The administrative structure for local governance has always existed in one form or the other since colonial period. However, the poser is how autonomous are they as a unit of government and to what extent are they effective. This study relying on available secondary data, adduced that local governments have constitutional responsibilities, its autonomy is greatly eroded by other higher tier governments, and that lack of autonomy impedes its effectiveness. Way forward suggested include, constitutional reforms, limited role for both state and federal governments and financial autonomy for effectiveness. Keywords: Local government, Autonomy, Effectiveness, Efficient-service, Decentralization
Motivational Strategies as Determinants of Lecturers’ Effectiveness in Nigerian Private Universities Amidst Covid-19 Lockdown: Evidence from Al-Hikmah University, Ilorin, Nigeria.
Authors:   Department of Food Science & Technology-Department of Nutrition and Dietetics Federal Polytechnic, Bauchi. Bauchi State, Nigeria, Lawal R. A. , Musa H , Adebusoye M. S. , Haruna U.S
Published: January 2022

Brevibacterium linens has long been recognized as an important dairy microorganism. This study investigated Assessment of Syneresis in yoghurt produced from fresh cow milk using Bervibacterium linens as starter culture. Bervibacterium linens was isolated from sample of cheese (procured from Jos metropolis). The milk samples were clarified to remove foreign materials, pasteurized at 65oC for 30min to destroy pathogenic materials and later cooled to temperature of 42oC and B. linens was inoculated in pasteurized milk to compare its potential as starter culture against common starter culture (L.bulgaricus and S. thermophlius) , the mixture allowed to ferment for 4 hrs. The semi- solid curds were homogenized; package and cool at 4oC and the same method was repeated for common starter yoghurt. Syneresis was determined by using centrifugal method. The result of syneresis of yoghurt produced Brevibacteriu linens as starter was significant (p<0.05) lower than that produced from common starter culture. The usage of B. linens as starter culture should be encouraged in dairy industries. Keywords: Syneresis, cow milk, yoghurt, Bervibacterium linens, starter culture.
Molecular based identification of Tem ß-lactamase and Tet a resistance gene in E. coli
Authors: Amjad Madiha , Akram Qaisar , Kauser Humara , Ali Azam , Ali Qurban
Published: February 2022

Escherichia coli is a universal bacterium causing infections in humans and
animal and serves as a major pathogen of urinary tract infections (UTI) and
Extraintestinal infection. The present study was conducted for current
antibiotic resistance pattern of E. coli and molecular detection of
resistance related gene in clinical isolates of E. coli. The study was a
hospital based, prospective study which was done for a period of twelve
months. This study was done by using the standard culture techniques for
urine, pus, semen and sputum samples, Maximum number was from samples of
urine 73 followed by pus 23 semen 2 and sputum 2. Hundred pathogenic E. coli
isolates was further identified by standard microbiology techniques such as
colony morphology, Gram staining and biochemical testing methods. Drug
resistance was evaluated by disc diffusion method and relevant drug
resistance gene detection done by Multiplex PCR. Out of 130 clinical samples
total (n=100) isolates were identified as E. coli and their susceptibility
patterns for different antibiotics were determined. Results showed that
Gentamicin among aminoglycosides and Colistin sulfate among polymyxin were
showed relatively less resistance in E. coli. Bacitracin, Ampicillin,
trimethoprim, Erythromycin, Tetracycline, Ciprofloxacin, Amoxicillin and
Piperacillin were found more resistant. Imepenum, Meropenum among ? lactam
were most effective drug. PCR was employed to identify resistance causing
gene. Among 100 pathogenic E. coli isolates 87% shown ampicillin resistance
encoded by Tem B lactamase gene and 86 % shown tetracycline resistance
causing by Tet A gene. Highest level of drug-resistance was observed against
ampicillin and tetracycline (AMP-TET) among clinical isolates of pathogenic
E. coli collected from hospitalized patients.
Rapid immunodetection assay based on somatic and excretory secretory antigen of fasciola species in large ruminants
Authors: Komal Maria , Afshan Kiran , Zafar Seemi , Khan Muhammad , Firasat Sabika , Qayyum Mazhar
Published: February 2022

Fasciolosis, caused by liver fluke species of the genus Fasciola, are well
recognized because of its high veterinary impact. Stool examination for
Fasciola eggs is not a sensitive method, and limited efforts to find a
reliable and cheaper means of detection are available. The present study
aimed to develop rapid diagnostic ELISA test against fasciolosis. The
excretory/secretory (ES) and somatic (SA) products of Fasciola helminths
were analyzed using polyacrylamide gel electrophoresis (PAGE).
Immunogenicity was evaluated by immunoblotting using hyperimmune sera raised
in rabbits and seroprevalence was determined by indirect ELISA. The results
of SA antigen of Fasciola species showed polypeptide bands ranged from
10kDa-100kDa, while ES antigen of Fasciola showed bands of 15kDa-55kDa. The
immunoblotting results showed the most prominent bands against ES antibodies
were 25, 35, 55-70, 100 and 250 kDa and SA antigens showed 10, 15-25, 35,
70, 100 and 250 kDa polypeptide bands. The sensitivity and specificity of
developed indirect ELISA for SA antigens was 95.45% and 87.1%, while for ES
antigens was 100% and 77.42% respectively. The overall seroprevalence
recorded for fascioliasis based on SA antigen was 39.8% and 29.8% for ES
antigen. The fasciolosis did not show significant association with host
type, sex, and age groups of examined animals, however significantly higher
infection was found in months of September and October. The result provides
sensitive in house immunodetection assay for diagnosis of fasciolosis
alternative to commercial kits with high import cost.
Vaccine Refusal Is Still Not Free Riding
Authors: Bradley Ethan , Navin Mark
Published: January 2022

In a recent article, "Can One Both Contribute to and Benefit from Herd Immunity?", Lucie White (2021) argues that vaccine refusal is more like free riding than we have claimed that it is. Here, we critically reply to White’s arguments.
Global Culture Reproduction Through The String Orchestra’ Repertoire

(The Role of Brandenburg Concerto III BWV 1084 J.S Bach toward the Skills and the musical Spirit of Strings Ensemble Students at the Pasundan University Music Study Program)
Authors: Matias Ferry , Lutfiansyah Abraham
Published: January 2022

The selection of repertoire on a musical ensemble is quite important, especially in the context of rehearsal in the non-professional string ensemble community. It is very common if there is a diversity of skill levels in each member. Such diversity will usually be a common obstacle when it comes to determining a shared repertoire. An overly difficult repertoire (advance) will be difficult for some members otherwise an easy one will create a bored atmosphere for members who are already proficient. Even the role of unbalanced work will make some members may struggle while others will become bored so that the rehearsal atmosphere is not conducive. The author observed that there is an interesting repertoire that is often used as an ensemble rehearsal material in the bowed string’s formation, namely Brandenburg Concerto no. III BWV 1048 Part III in G Major by Johan Sebastian Bach for 3 violins, 3 violas, 3 cellos and 1 double bass. This work is often used as an alternative work together in the community environment of string orchestras in Bandung, and based on the observation of the author of this work is often used in several workshops and ensemble learning materials, with a relatively balanced role, this complex-sounding work has techniques and finger positions that can still be reached by players in the skill range level 3-5 ABRSM. The authors collected data through observations, interviews and documentation on Unpas Music Study Program students who had played this work. After being described and analyzed, the authors found that this work had a significant role in improving ensemble skills playing in string ensembles that would indirectly also improve their individual skills especially for advanced entry-level string instrument students.

Keywords: Brandenburg Concerto III, String Orchestra, Music Ensembles, Baroque, Bach.
The Meaning of Tri Tangtu Principles in Sundanese Traditional Game “Oray-orayan”
Authors: Nurmalinda Erna
Published: January 2022

In West Java (Bandung) there are copious traditional games that are actually still played by children. But because of technological advances and the absence of fields for playing, the traditional games is now sidelined and even forgotten. Games are offered now, not only traditional games but also the games that sophisticated technological based derived from abroad. The traditional games of West Java that used to be played have been put aside. Traditional “Oray-orayan” game is a game of boys and girls known since ancient times. Besides educational elements (choir, sports and sensitivity) this game is also containing a fun entertainment for children. In Traditional Games “Oray-orayan” the desires can arise from thoughts or deeds, then the mind or knowledge evokes desire, after that there is a process of thought so that desire can manifested in action. The pattern of the three relationships in Tritangtu can be known from the structure of objects or artifacts. Tritangtu reflects and is represented in all systems and sub systems in Sundanese culture such as the State system, Social system, Legal system, Art system and others that relates to Tritangtu principles.

Keywords; Game, Traditional, Oray-orayan, Meaning, Tritangtu.
Affixation Category of Palembang Malay Language Reviewed From Perspective
of Morphological Typology
Authors: Thamrin Husni
Published: January 2022

Abstract
This research is related to affixation category of Palembang Malay language, which is a regional part of the Sumatra region exactly South Sumatra. In particular, this study uses category of affixation in the form of prefixes and suffixes (suffiks) used by Dryer's (2013) in researching the Nualu language in Seram island which belongs to the Polynesian Malay ethnic. This research reveals that on Palembang Malay language affixation, the first affixation category was the form of 6 (six) categories of prefixes (awalan) in Palembang Malay language, among others; N-, di-, peN-, be-, te-, and se-.Second, there are found 5 (five) types of suffixes (akhiran) in Palembang Malay language, such as; -ke, -la, -an, -nyo, and –i. The third is found 3 (three) simulfix (awalan-akhiran) which is the type of bound form of the prefix one with another prefix, such as: ke-.. . -an, pe-. . . -an, and be-. -an. Finally, there were found 3 (three) main categories of morphophonemic process prefixes in Palembang Malay language, such as; a) there are four types of prefixesN-in Malay language Palembang has many allomorphs: m, n, ny, ng. b) there are six types of prefixespeN- connected with words, so the prefix will change to: pem-, pen-, peny-, peng-, pel-, orpe-. c)there are four prefixesbe- that has allomorphs bel-, ber, and be- .The Grand theory approach used in this study has been stated by Velupillai (2012) and Lieber (2009).
Binaural Beat of Bringbrung Music
Authors: Permadi Putra Made Bagus
Published: January 2022

Bringbrung is a ritual music in the tradition of society in the Kampung Cidadap Hilir, Ledeng, Kota Bandung. In each of Bringbrung performances, there is always a trance from the player and the audience. This phenomenon becomes the background of this research. One of the musical elements that are thought to be highly influential stimulates trance is binaural sensation. This article explains how the music of Bringbrung can produce binaural sensation so that it can stimulate trance on the players and the audience. The research methods used in this article use qualitative methods with a phenomenological approach. The data was collected through observation, interview notes taking, triangulation, and focus group discussion. The analyses of this research were taken through analysis of reduction data, data presentation, and conclusion. The results of the research that has been done show that binaural sensation has a significant contribution in stimulating trance during the show Bringbrung. Binaural sensation generated from the frequency difference of each Bringbrung instrument that has a range of 0 - 25 Hz. The binaural sensation produced by Bringbrung music is certainly one of the proofs that ritual music in Indonesia has a therapeutic effect. Advanced research in the field is very important for the development of music therapy based on the musical traditions of Indonesia.

Keywords: music therapy, psychology of music, psychoacoustic
A Literature Analysis of “Kering” By Iwan Simatupang
Authors: Sianipar Rosmani
Published: January 2022

Iwan Simatupang the great writer was born on January 18, 1928. Lots of his works have been translated into various languages, while the demand for reprints continues to increase. Iwan Simatupang's "Kering" is not only in a physical sense but is more contemplative in nature. With the adventures carried out, he describes how the actors are afflicted with psychological, spiritual, ideas, and ready to be swallowed by termites so that it becomes pathetic. Iwan, in channelling his ideas and thoughts is by the understanding of the philosophers he admires, namely existentialist philosophers. Iwan can also be called a nihilist. He negates all old values and confirms standard values. He tried to overcome something he felt was an obstacle in the creation of his writing. The flow of thoughts he emits in a firm, yet artistic form. This is most evident in the novel 'Kering'. He ignores the rules, neither in his life nor in formulating his thoughts. If people want to characterize the nature of his mind and wisdom, it is fierce, like a sailboat hit by the waves of the ocean.

Keywords: irrationalism, parallelism, philosophy of existentialism,
Influence of Light Intensity on Tobacco Responses to Drought Stress
Authors: Rasool Brwa
Published: January 2022

The influence of high irradiance, drought stress and their cross-talk were explored in tobacco plants (Nicotiana tobaccum) grown under low light (250 ?mol m-2 s-1) irradiance (LL) and high (1600 ?mol m-2 s-1) irradiance (HL) then exposed to water deficient condition for 7 or 14 days. The detached leaves of HL-treated plants showed less water loss compared to LL plants. The HL-treated and 7 days drought-stressed plants had higher fresh and dry weights, as well as water content than the LL and drought-stressed leaves. The survival rate in 21 days drought-stressed plants after 3 days of re-watering was 50% in HL-grown and 0% in LL-grown plants. 

A transcriptome profiling analysis of the tobacco responses to light intensity highlights the increased abundance of a large group of drought-related transcripts including DROUGHT-RESPONSIVE ELEMENT BINDING FACTORS (DREBs), C-REPEAT/DROUGHT-RESPONSIVE BINDING FACTOR 1 (CBF1), GLYCINE-RICH RNA BINDING PROTEINS (GRPs), WRKY33 and MYCs transcription factors, as well as zeaxanthin epoxidase, which play as a regulator of plant responses to water deficient condition.

These findings identify light-dependent changes in the cell redox state that limit water loss and enhance plant responses to drought stress.
LoRa: A Proposed Connectivity Technology for Internet of Things Applications in the Kurdistan Region of Iraq
Authors: Ahmad Sarko Salahadin , Saeed Bakhtiar Ibrahim
Published: January 2022

The Internet of Things (IoT) has become one of the most important trends of this century. Recent advances in many different communication technologies and protocols, and access to low-cost and low-power microcontrollers and sensors have made it more prevalent.

Globally, most IoT adoption comes from developed countries such as the United States, United Kingdom, Western Europe, and East Asia, as these countries have a well-established nationwide IoT infrastructure. In contrast, the IoT application in developing countries such as Kurdistan Region of Iraq (KRI) remains restricted as deployment faces main challenges. On the one hand, selecting the right technology for IoT applications can be complicated with so many IoT connectivity technologies such as Cellular, Wi-Fi, Low Power Wide Area Network (LPWAN), Bluetooth, and ZigBee on the market. On the other hand, the main impediment seems to be the lack of IoT infrastructure technologies in developing countries.

In this paper, a comparative study on the main LPWAN technologies has been carried out in terms of cost and coverage of the network and range to become connectivity technology for IoT applications in the KRI. Based on the study, LoRa technology has been presented and proposed as the optimal connectivity technology to establish an IoT infrastructure for the KRI. The proposed network enables the deployment of IoT applications easier and faster. In addition, various LoRa based IoT applications have been proposed that benefit many sectors. A potential application has been set out as a case study to show case the significance of the new infrastructure.

The proposed LoRaWAN infrastructure can accommodate a vast range of applications and will revolutionize IoT applications in the KRI as it enables data transmission over a long distance while using extremely low power.
Pear Fruits Ripening Response to Ethylene and Temperature Treatments
Authors: Tahir Ikbal MuhammedGharib
Published: January 2022

A factorial experiment with complete randomized design carried out in Erbil governorate, Iraq on two varieties of pears (Pyrus communis L.) spadona and compote cv. to investigate the effects of ethylene and temperature treatments on fruits ripening. The experiment includes four treatments; the control (cold storage at 0±1 C° and 85-90 relative humidity), the second was putting the fruits in ambient temperature with exposure to ethylene gas (300 mg/l) for 24 hours, third and fourth treatments were putting the fruits in the ripening cabinet at 20 C° either for 8 days, or 12 days.  Results indicate that compote variety was differing significantly in decreasing weight loss and fruits firmness and increasing fruits peel pigments content and peroxidase enzyme activity compared to spadona variety. Slower ripening process was gained from cold storage treatment where the fruits remain non-ripened compared to other treatments, whereas ripening fruits at 20C° for 12 days fastened the ripening process by giving highest TSS, and lowest fruits firmness, in addition to percent of weight loss. For the condition of northern Iraq, the best treatment for ripening pear fruits is treating with ethylene gas or ripening the fruits at 20C° for 8 days.
PENGEMBANGAN BUKU AJAR ALJABAR LINIER BERBASIS MATLAB MOBILE UNTUK MENUNJANG PEMBELAJARAN DARING
Authors: Lusiana Restu , Setyansah Reza Kusuma
Published: January 2022

Learning mathematics online, especially in Linear Algebra courses requires mathematical software-based teaching materials, to strengthen the understanding of numerical concepts. The purpose of this research is to produce MATLAB Mobile-based textbooks that are suitable to support online learning. This development research uses a 4-D model containing 4 stages, namely Define, Design, Develop, and Disseminate. This research was conducted at the Mathematics Education Study Program, the University of PGRI Madiun with 20 students as the subject of the fourth semester. The research instrument and data collection in this study used validation sheets, response questionnaires, and learning outcomes tests. Data analysis of the validation sheet and questionnaire used the Likert scale and the Guttman scale, while the data analysis of the learning outcomes test used the Normalized Gain Score (n-Gain). This study produced a Linear Algebra textbook based on MATLAB Mobile to support online learning during the Covid 19 pandemic with a validity percentage of 86,5% (valid), practicality percentage 83,4% (practical), and an n-Gain score of 46,7 (moderately effectiveness). So that the textbooks developed are suitable to support online learning.
DESAIN VIDEO PEMBELAJARAN MATEMATIKA MATERI TURUNAN FUNGSI
Authors: Hali Fitriyani , Farman Farman
Published: January 2022

AbstrakPenelitian ini bertujuan untuk mendesain video pembelajaran matematika materi turunan fungsi yang layak digunakan bagi siswa SMA Kelas IX. Metode penelitian yang digunakan dalam penelitian ini adalah jenis penelitian pengembangan. Penelitian pengembangan merupakan penelitian yang berorientasi untuk menghasilkan produk tertentu dan menguji kelayakan produk tersebut. Desain video pembelajaran materi turunan dilakukan dengan langkah 4-D yaitu langkah define (pendefinisian), design (perancangan) develop (pengembangan) dan disseminate (penyebaran). Subjek uji coba terbatas penelitian ini adalah siswa kelas XI SMA Negeri 10 Kendari yang berjumlah 21 siswa. Instrumen yang digunakan dalam penelitian ini berupa angket lembar validasi dan angket respon siswa yang disusun dalam google form. Hasil validasi ahli materi dan ahli media menunjukkan bahwa desain video pembelajaran materi turunan berada dalam kriteria sangat valid. Hasil dari rerata indikator respon siswa yang terdiri atas fungsi dan manfaat, penyajian video serta bahasa dan tipografi menunjukkan persentase 87,3% yang berarti respon siswa menunjukkan sangat positif terhadap desain video pembelajaran yang dikembangkan. Dengan demikian video pembelajaran matematika materi turunan fungsi layak digunakan sebagai media belajar interaktif secara mandiri di sekolah atau di rumah dalam rangka menarik minat siswa dan memudahkan siswa dalam memahami turunan fungsi.  Kata kunci: matematika; turunan fungsi; video pembelajaran; AbstractThis study aims to design a mathematics learning video for derivative material that is suitable for use for class IX high school students. The research method used in this research is development research. Development research is research that is oriented to produce certain products and test the feasibility of these products. The design of the derived material learning video is carried out in a 4-D step, namely the define, design develop and disseminate. The subjects of the limited trial of this study were students of class XI SMA Negeri 10 Kendari, totaling 21 students. The instrument used in this study was a questionnaire validation sheet and student response questionnaire compiled in google form. The results of the validation of material experts and media experts show that the design of the derived material learning video is within the valid criteria. The results of the average student response indicators consisting of functions and benefits, video presentation as well as language and typography showed a percentage of 87.3% which means that responses showed a very positive attitude towards the learning video design developed. Thus the mathematics learning video for derivative is appropriate to be used as media for independent interactive learning at school or at home in order to attract students' interest and make it easier for students to understand derivatives.Keywords: derivative; learning video; mathematics
PENGARUH MODEL REALISTIC MATHEMATICS EDUCATION TERHADAP KEMAMPUAN LITERASI MATEMATIKA DITINJAU DARI SELF EFFICACY SISWA
Authors: Istiqomah Prastika , Kamid Kamid , Hasibuan Muhammad Haris Effendi
Published: January 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penerapan model pembelajaran realistic mathematics education (RME) terhadap kemampuan  literasi matematika siswa, dan pengaruh self-efficacy terhadap kemampuan literasi matematika siswa. Penelitian ini merupakan penelitian eksperimen yang menggunakan posttest only control design. Populasi penelitian ini adalah seluruh siswa kelas VIII SMP Negeri 9 Kota Jambi tahun ajaran 2021/2022 sebanyak 228 siswa dan terbagi menjadi 7 kelas. Dalam penelitian ini, sampel yang digunakan adalah sebanyak 68 siswa yang terbagi menjadi dua kelas (kelas eksperimen I dan kelas kontrol). Sampel di tentukan dengan teknik Simple Random Sampling. Instrumen yang digunakan dalam penelitian ini ialah angket self-efficacy dan tes kemampuan literasi matematika. Data yang diperoleh dianalisis menggunakan uji ANOVA dua jalur. Hasil penelitian ini yaitu Model pembelajaran RME lebih efektif mempengaruhi kemampuan literasi matematika dibandingkan dengan pembelajaran konvensional, serta self-efficacy dengan kategori tinggi dan sedang lebih mempengaruhi kemampuan literasi matematika dibandingkan self-efficacy siswa dengan kategori rendah.