bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Multiplexed Marker Sets to Identify the Most Relevant Poplar Species for Breeding
Authors: Schroeder Hilke , Kersten Birgit , Fladung Matthias
Published: December 2017

Within the genus Populus, about 30 species are classified into six sections, of which some are cross-compatible. Besides naturally occurring hybrids, huge breeding programs have led to a high number of artificially produced hybrids, for which the determination of genetically involved species by morphological characteristics is often difficult. This necessitates the use of molecular markers for the identification of both maternal as well as paternal species, and in the case of complex hybrids, the genealogy. For this reason, we developed new chloroplast and nuclear markers for the differentiation of up to 19 poplar species, with one to 32 individuals per species regularly used in breeding programs based on already known barcoding, other chloroplast regions, and nuclear genes of interest. We developed methods to identify species by either species-specific nucleotide variations or, when no initial information for the species was given, by using a set of markers either in a procedure of exclusion or in a multiplexed marker set. The developed markers can all be used with low-cost equipment, and some can additionally be applied using a genetic analyzer. We combined these markers in multiplexes for a very fast and easy-to-use application for the identification of poplar species and their hybrids.
Spatiotemporal Variations and Driving Factors of Air Pollution in China
Authors: Zhan Dongsheng , Kwan Mei-Po , Zhang Wenzhong , Wang Shaojian , Yu Jianhui
Published: December 2017

In recent years, severe and persistent air pollution episodes in China have drawn wide public concern. Based on ground monitoring air quality data collected in 2015 in Chinese cities above the prefectural level, this study identifies the spatiotemporal variations of air pollution and its associated driving factors in China using descriptive statistics and geographical detector methods. The results show that the average air pollution ratio and continuous air pollution ratio across Chinese cities in 2015 were 23.1 ± 16.9% and 16.2 ± 14.8%. The highest levels of air pollution ratio and continuous air pollution ratio were observed in northern China, especially in the Bohai Rim region and Xinjiang province, and the lowest levels were found in southern China. The average and maximum levels of continuous air pollution show distinct spatial variations when compared with those of the continuous air pollution ratio. Monthly changes in both air pollution ratio and continuous air pollution ratio have a U-shaped variation, indicating that the highest levels of air pollution occurred in winter and the lowest levels happened in summer. The results of the geographical detector model further reveal that the effect intensity of natural factors on the spatial disparity of the air pollution ratio is greater than that of human-related factors. Specifically, among natural factors, the annual average temperature, land relief, and relative humidity have the greatest and most significant negative effects on the air pollution ratio, whereas human factors such as population density, the number of vehicles, and Gross Domestic Product (GDP) witness the strongest and most significant positive effects on air pollution ratio.
Individual Differences, Self-Efficacy, and Chinese Scientists’ Industry Engagement
Authors: Zhao Zhiyan , Cai Jianfeng
Published: December 2017

Research indicates that non-commercial and informal university–industry interactions, which are defined as academic engagement, account for a larger part and play a more important role than commercialization in academic knowledge transfer in China. This paper aims to explore the effect of Chinese scientists’ individual differences on academic engagement via social cognitive theory. This study attempts to provide an interpretation of how individual differences affect Chinese academics’ industrial engagement through self-efficacy. Based on data collection from Chinese universities, these analysis results show that gender, academic rank, industry connections, and previous industrial experience are significantly associated with Chinese scientists’ industry engagement. Furthermore, a scientist’s self-efficacy in industry collaborations is also influenced by these four individual factors. The mediating effects of self-efficacy on the relationship between individual differences and academic engagement are confirmed by empirical analysis results. Implications, limitations, and future research directions are discussed at the end of this paper.
Edible Scaffolds Based on Non-Mammalian Biopolymers for Myoblast Growth
Authors: Enrione Javier , Blaker Jonny , Brown Donald , Weinstein-Oppenheimer Caroline , Pepczynska Marzena , Olguín Yusser , Sánchez Elizabeth , Acevedo Cristian
Published: December 2017

In vitro meat has recently emerged as a new concept in food biotechnology. Methods to produce in vitro meat generally involve the growth of muscle cells that are cultured on scaffolds using bioreactors. Suitable scaffold design and manufacture are critical to downstream culture and meat production. Most current scaffolds are based on mammalian-derived biomaterials, the use of which is counter to the desire to obviate mammal slaughter in artificial meat production. Consequently, most of the knowledge is related to the design and control of scaffold properties based on these mammalian-sourced materials. To address this, four different scaffold materials were formulated using non-mammalian sources, namely, salmon gelatin, alginate, and additives including gelling agents and plasticizers. The scaffolds were produced using a freeze-drying process, and the physical, mechanical, and biological properties of the scaffolds were evaluated. The most promising scaffolds were produced from salmon gelatin, alginate, agarose, and glycerol, which exhibited relatively large pore sizes (~200 μm diameter) and biocompatibility, permitting myoblast cell adhesion (~40%) and growth (~24 h duplication time). The biodegradation profiles of the scaffolds were followed, and were observed to be less than 25% after 4 weeks. The scaffolds enabled suitable myogenic response, with high cell proliferation, viability, and adequate cell distribution throughout. This system composed of non-mammalian edible scaffold material and muscle-cells is promising for the production of in vitro meat.
Novel Development of Phosphate Treated Porous Hydroxyapatite
Authors: Doi Kazuya , Abe Yasuhiko , Kobatake Reiko , Okazaki Yohei , Oki Yoshifumi , Naito Yoshihito , Prananingrum Widyasri , Tsuga Kazuhiro
Published: December 2017

Phosphoric acid-etching treatment to the hydroxyapatite (HA) surface can modify the solubility calcium structure. The aim of the present study was to develop phosphate treated porous HA, and the characteristic structures and stimulation abilities of bone formation were evaluated to determine its suitability as a new type of bone graft material. Although the phosphoric acid-etching treatment did not alter the three-dimensional structure, a micrometer-scale rough surface topography was created on the porous HA surface. Compared to porous HA, the porosity of phosphate treated porous HA was slightly higher and the mechanical strength was lower. Two weeks after placement of the cylindrical porous or phosphate treated porous HA in a rabbit femur, newly formed bone was detected in both groups. At the central portion of the bone defect area, substantial bone formation was detected in the phosphate treated porous HA group, with a significantly higher bone formation ratio than detected in the porous HA group. These results indicate that phosphate treated porous HA has a superior surface topography and bone formation abilities in vivo owing to the capacity for both osteoconduction and stimulation abilities of bone formation conferred by phosphoric acid etching.
Predicting the Performance of Organic Corrosion Inhibitors
Authors: Winkler David
Published: December 2017

The withdrawal of effective but toxic corrosion inhibitors has provided an impetus for the discovery of new, benign organic compounds to fill that role. Concurrently, developments in the high-throughput synthesis of organic compounds, the establishment of large libraries of available chemicals, accelerated corrosion inhibition testing technologies, and the increased capability of machine learning methods have made discovery of new corrosion inhibitors much faster and cheaper than it used to be. We summarize these technical developments in the corrosion inhibition field and describe how data-driven machine learning methods can generate models linking molecular properties to corrosion inhibition that can be used to predict the performance of materials not yet synthesized or tested. We briefly summarize the literature on quantitative structure–property relationships models of small organic molecule corrosion inhibitors. The success of these models provides a paradigm for rapid discovery of novel, effective corrosion inhibitors for a range of metals and alloys in diverse environments.
Prevalence and Effects of Functional Vitamin K Insufficiency: The PREVEND Study
Authors: Riphagen Ineke , Keyzer Charlotte , Drummen Nadja , De Borst Martin , Beulens Joline , Gansevoort Ron , Geleijnse Johanna , Muskiet Frits , Navis Gerjan , Visser Sipke , Vermeer Cees , Kema Ido , Bakker Stephan
Published: December 2017

Matrix Gla Protein (MGP) is a strong vitamin K-dependent inhibitor of soft tissue calcification. We assessed the prevalence of functional vitamin K insufficiency, as derived from plasma desphospho-uncarboxylated MGP (dp-ucMGP), and investigated whether plasma dp-ucMGP is associated with all-cause and cardiovascular mortality in a large general population-based cohort. We included 4275 subjects (aged 53 ± 12 years, 46.0% male) participating in the prospective general population-based Prevention of Renal and Vascular End-Stage Disease (PREVEND) study. The prevalence of functional vitamin K insufficiency (i.e., dp-ucMGP > 500 pmol/L) was 31% in the total study population. This prevalence was significantly higher among elderly and subjects with comorbidities like hypertension, type 2 diabetes, chronic kidney disease, and cardiovascular disease (~50%). After 10 years of follow-up, 279 subjects had died, with 74 deaths attributable to cardiovascular causes. We found significant J-shaped associations of plasma dp-ucMGP with all-cause (linear term: hazard ratio (HR) (95% confidence interval (CI)) = 0.20 (0.12–0.33), p < 0.001; squared term: 1.14 (1.10–1.17), p < 0.001) and cardiovascular mortality (linear term: 0.12 (0.05–0.27), p < 0.001; squared term: 1.17 (1.11–1.23), p < 0.001). These associations remained significant after adjustment for potential confounders. Whether the correction of vitamin K insufficiency improves health outcomes needs to be addressed in future prospective intervention studies.
The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14
Authors: Zhao Ningning , Zhang An-Sheng , Wortham Aaron , Jue Shall , Knutson Mitchell , Enns Caroline
Published: December 2017

Loss of p53’s proper function accounts for over half of identified human cancers. We identified the metal transporter ZIP14 (Zinc-regulated transporter (ZRT) and Iron-regulated transporter (IRT)-like Protein 14) as a p53-regulated protein. ZIP14 protein levels were upregulated by lack of p53 and downregulated by increased p53 expression. This regulation did not fully depend on the changes in ZIP14’s mRNA expression. Co-precipitation studies indicated that p53 interacts with ZIP14 and increases its ubiquitination and degradation. Moreover, knockdown of p53 resulted in higher non-transferrin-bound iron uptake, which was mediated by increased ZIP14 levels. Our study highlights a role for p53 in regulating nutrient metabolism and provides insight into how iron and possibly other metals such as zinc and manganese could be regulated in p53-inactivated tumor cells.
Normal Diet within Two Postoperative Days—Realistic or Too Ambitious?
Authors: Grass Fabian , Schäfer Markus , Demartines Nicolas , Hübner Martin
Published: December 2017

Enhanced Recovery After Surgery (ERAS) protocols advocate early postoperative resumption of normal diet to decrease surgical stress and prevent excessive catabolism. The aim of the present study was to identify reasons for delayed tolerance of normal postoperative diet. This was a retrospective analysis including all consecutive colorectal surgical procedures since May 2011 until May 2017. Data was prospectively recorded by an institutional data manager in a dedicated database. Uni- and multivariate risk factors associated with delayed diet (beyond POD 2) were identified by multiple logistic regression among demographic, surgery- and modifiable pre- and intraoperative ERAS-related items. In a second step, univariate analysis was performed to compare surgical outcomes for patients with early vs. delayed oral intake. The study cohort consisted of 1301 consecutive colorectal ERAS patients. Herein, 691 patients (53%) were able to resume normal diet within two days of surgery according to ERAS protocol, while in 610 patients (47%), a delay in tolerance of normal diet was observed. Male gender was independently correlated to early tolerance (Odds Ratio (OR) 0.66; 95% Confidence Interval (CI) 0.46–0.84, p = 0.002), while ASA score ≥ 3 (OR 1.60; 95% CI 1.12–2.28, p = 0.010), abdominal drains (OR 1.80; 95% CI 1.10–2.49, p = 0.020), right colectomy (OR 1.64; 95% CI 1.08–2.49, p = 0.020) and Hartmann reversal (OR 2.61; 95% CI 1.32–5.18, p = 0.006) constituted risk factors for delayed tolerance of normal diet. Patients with delayed resumption of normal diet experienced more overall (Clavien grade I–V) (47% vs. 21%, p < 0.001) and major (Clavien grade IIIb–V) (11% vs. 4%, p < 0.001) complications and had a longer length of stay (9 ± 5 vs. 5 ± 4 days, p < 0.001). Over half of patients could not tolerate early enteral realimentation and were at higher risk for postoperative complications. Prophylactic drain placement was the only independent modifiable risk factor for delayed oral intake.
Biocompatibility Assessment of Conducting PANI/Chitosan Nanofibers for Wound Healing Applications
Authors: Moutsatsou Panagiota , Coopman Karen , Georgiadou Stella
Published: December 2017

As electroactive polymers have recently presented potential in applications in the tissue engineering and biomedical field, this study is aiming at the fabrication of composite nanofibrous membranes containing conducting polyaniline and at the evaluation of their biocompatibility. For that purpose, conducting polyaniline–chitosan (PANI/CS) defect free nanofibres of different ratios (1:3; 3:5 and 1:1) were produced with the electrospinning method. They were characterized as for their morphology, hydrophilicity and electrical conductivity. The membranes were then evaluated for their cellular biocompatibility in terms of cell attachment, morphology and cell proliferation. The effect of the PANI content on the membrane properties is discussed. Increase in PANI content resulted in membranes with higher hydrophobicity and higher electrical conductivity. It was found that none of the membranes showed any toxic effects on osteoblasts and fibroblasts, and that they all supported cell attachment and growth, even to a greater extent than tissue culture plastic. The membrane with the PANI/CS ratio 1:3 supports better cell attachment and proliferation for both cell lines due to a synergistic effect of hydrophilicity retention due to the high chitosan content and the conductivity that PANI introduced to the membrane.
Exploring Performance Determinants of China’s Cable Operators and OTT Service Providers in the Era of Digital Convergence—From the Perspective of an Industry Platform
Authors: Wan Xing , Cenamor Javier , Chen Jing
Published: December 2017

This paper investigates key determinants of business performance in China’s video industry in the era of digital convergence. Specifically, we analyze China’s OTT (over-the-top) service providers and cable operators based on the perspective of an industry platform, which acts as the core module of a business ecosystem and is capable of facilitating and coordinating interdependence among different agents. Panel data models are established to empirically explore what factors impact the performance of these two types of players. The findings demonstrate that both platform use and the size of an installed base are crucial for the determinants of the performance of OTT service providers and cable operators. An online video platform can also benefit from an increasing proportion of mobile viewers by implementing a multi-screen strategy. Further, an OTT service provider can profit from the interaction between its installed base and UGC (user-generated content), while cable operators can take advantage of positive feedback between their demand side and supply side.
Reciprocal Relations between Official Development Assistance Recipient and Donor Countries: Case of South Korean Overseas Construction Business and Southeast Asian Countries’ Economy
Authors: Lee Suk-Won , Kim Jae-Jun , Kim Ju-Hyung
Published: December 2017

In developing countries, official development assistance (ODA) is generally perceived to be an alternative means to develop infrastructure. Donor countries may expect benefits such as increased construction project orders in recipient countries. However, it remains arguable whether ODA contributes to reciprocal relations between recipient and donor countries. The case of South Korea can provide empirical data given that its government has expanded the amount of ODA to encourage overseas construction business while supporting Southeast Asian countries. In this research, gross national income (GNI), gross domestic product (GDP), foreign direct investment (FDI), and construction project orders awarded by South Korean construction companies in Vietnam, Bangladesh and Sri Lanka are analyzed according to the variation of ODA awarded by South Korea. The analysis results show that the influence of ODA upon economic situation of recipient countries varies according to their economic volume and development policy. From the donor country’s perspective, enhanced performance of construction business can be expected by means of cooperation with local construction business.
Micro-Study of the Evolution of Rural Settlement Patterns and Their Spatial Association with Water and Land Resources: A Case Study of Shandan County, China
Authors: Ma Libang , Guo Xiaodong , Tian Yaya , Wang Yongli , Chen Meimei
Published: December 2017

The balance between population and water and land resources is an important part of regional sustainable development. It is also significant for the ecological civilization in China and can help solve the Three Rural Issues (agriculture, countryside and farmers) in China. The Silk Road Economic Belt and Maritime Silk Road in twenty-first Century Strategy have brought new opportunities for the Hexi Corridor, which is facing challenges in the sustainable development of rural settlements. In this paper, we analyzed the temporal-spatial differentiation of rural settlement patterns in Shandan County of Hexi Corridor and studied the spatial association between rural settlements and water-land resources. Results show that the total area of rural settlement patches (CA), the number of rural settlement patches (NP), the mean patch area (MPS), the maximum patch areas (MAXP), the minimum patch areas (MINP) and the density of rural settlement patches (PD) changed more rapidly from 1998 to 2008 than from 2008 to 2015. In the second period, the indices mentioned before did not change significantly. The kernel density of rural settlements is basically consistent in three periods. Rural settlements mainly distribute along major roads and the hydrographic network and the kernel density of rural settlements decreases in the direction away from these roads and the hydrographic network. In addition, rural settlements in Shandan County are densely distributed in some regions and sparsely distributed in other regions. The dispersion degree of rural settlements increased from 1998 to 2008 and tended to be stable after 2008. These lead to the dispersion, hollowing and chaos of rural settlements in Shandan County. The spatial distribution of rural settlements in Shandan County is closely related to that of cultivated land and the hydrographic network. Our results might provide a theoretical basis for the reasonable utilization of water and land resources in Shandan County. Ultimately, a balance between population and water and land resources and regional sustainable development can be achieved.
Measuring Water Transport Efficiency in the Yangtze River Economic Zone, China
Authors: He Dan , Gao Peng , Sun Zhijing , Lau Yui-yip
Published: December 2017

Water transport, a component of integrated transport systems, is a key strategic resource for achieving sustainable economic and social development, particularly in the Yangtze River Economic Zone (YREZ). Unfortunately, systematic studies on water transport efficiency are not forthcoming. Using Data Envelopment Analysis (DEA) and the Malmquist index as a model framework, this paper measures water transport efficiency in YREZ, conducts spatial analysis to identify the leading factors influencing efficiency, and provides scientific evidence for a macroscopic grasp of water transport development and the optimization of YREZ. The results indicate that water transport technical efficiency (TE) in YREZ is low and in fluctuating decline. Therefore, it has seriously restricted performance and improvements in the service function. Additionally, the spatial pattern of TE has gradually changed from complexity and dispersion to clarity and contiguity with a larger inter-provincial gap. Water transport efficiency has slightly improved through technological change (TECHch), whereas deteriorating pure technical efficiency change (PEch) is the main cause of a TE decrease. According to our findings, decision-makers should consider strengthening intra-port competition and promoting water transport efficiency.
Gravity Modes Reveal the Internal Rotation of a Post-mass-transfer Gamma Doradus/Delta Scuti Hybrid Pulsator in Kepler Eclipsing Binary KIC 9592855
Authors: Guo Z. , Gies D. R. , Matson R. A.
Published: December 2017

We report the discovery of a post-mass-transfer Gamma Doradus/Delta Scuti hybrid pulsator in the eclipsing binary KIC 9592855. This binary has a circular orbit, an orbital period of 1.2 days, and contains two stars of almost identical masses (

). However, the cooler secondary star is more evolved (

), while the hotter primary is still on the zero-age-main-sequence (

). Coeval models from single-star evolution cannot explain the observed masses and radii, and binary evolution with mass-transfer needs to be invoked. After subtracting the binary light curve, the Fourier spectrum shows low-order pressure-mode pulsations, and more dominantly, a cluster of low-frequency gravity modes at about 2 day−1. These g-modes are nearly equally spaced in period, and the period spacing pattern has a negative slope. We identify these g-modes as prograde dipole modes and find that they stem from the secondary star. The frequency range of unstable p-modes also agrees with that of the secondary. We derive the internal rotation rate of the convective core and the asymptotic period spacing from the observed g-modes. The resulting values suggest that the core and envelope rotate nearly uniformly, i.e., their rotation rates are both similar to the orbital frequency of this synchronized binary.
The Temporal and Spatial Scales of Density Structures Released in the Slow Solar Wind During Solar Activity Maximum
Authors: Sanchez-Diaz E. , Rouillard A. P. , Davies J. A. , Lavraud B. , Pinto R. F. , Kilpua E.
Published: December 2017

In a recent study, we took advantage of a highly tilted coronal neutral sheet to show that density structures, extending radially over several solar radii (R
s), are released in the forming slow solar wind approximately 4–5 R
s above the solar surface. We related the signatures of this formation process to intermittent magnetic reconnection occurring continuously above helmet streamers. We now exploit the heliospheric imagery from the Solar Terrestrial Relation Observatory (STEREO) to map the spatial and temporal distribution of the ejected structures. We demonstrate that streamers experience quasi-periodic bursts of activity with the simultaneous outpouring of small transients over a large range of latitudes in the corona. This cyclic activity leads to the emergence of well-defined and broad structures. Derivation of the trajectories and kinematic properties of the individual small transients that make up these large-scale structures confirms their association with the forming slow solar wind (SSW). We find that these transients are released, on average, every 19.5 hr, simultaneously at all latitudes with a typical radial size of 12 R
s. Their spatial distribution, release rate, and three-dimensional extent are used to estimate the contribution of this cyclic activity to the mass flux carried outward by the SSW. Our results suggest that, in interplanetary space, the global structure of the heliospheric current sheet is dominated by a succession of blobs and associated flux ropes. We demonstrate this with an example event using STEREO-A in situ measurements.
A Comprehensive Rotational Study of Interstellar Iso-propyl Cyanide up to 480 GHz
Authors: Kolesniková L. , Alonso E. R. , Mata S. , Cernicharo J. , Alonso J. L.
Published: December 2017

A detailed analysis of the rotational spectra of the interstellar iso-propyl cyanide has been carried out up to 480 GHz using three different high-resolution spectroscopic techniques. Jet-cooled broadband chirped pulse Fourier transform microwave spectroscopy from 6 to 18 GHz allowed us to measure and analyze the ground-state rotational transitions of all singly substituted 13C and 15N isotopic species in their natural abundances. The monohydrate of iso-propyl cyanide, in which the water molecule bounds through a stronger O–H⋯N and weaker bifurcated (C–H)2⋯O hydrogen bonds in a C

s
configuration, has also been detected in the supersonic expansion. Stark-modulation spectroscopy in the microwave and millimeter wave range from 18 to 75 GHz allowed us to analyze the vibrational satellite pattern arising from pure rotational transitions in the low-lying vibrational excited states. Finally, assignments and measurements were extended through the millimeter and submillimeter wave region. The room temperature rotational spectra made possible the assignment and analysis of pure rotational transitions in 19 vibrationally excited states. Significant perturbations were found above 100 GHz in most of the observed excited states. Due to the complexity of the interactions and importance of this astrophysical region for future radioastronomical detection, both a graphical plot approach and a coupled fit have been used to assign and measure almost 10,000 new lines.
xCOLD GASS: The Complete IRAM 30 m Legacy Survey of Molecular Gas for Galaxy Evolution Studies
Authors: Saintonge Amélie , Catinella Barbara , Tacconi Linda J. , Kauffmann Guinevere , Genzel Reinhard , Cortese Luca , Davé Romeel , Fletcher Thomas J. , Graciá-Carpio Javier , Kramer Carsten , Heckman Timothy M. , Janowiecki Steven , Lutz Katharina , Rosario David , Schiminovich David , Schuster Karl , Wang Jing , Wuyts Stijn , Borthakur Sanchayeeta , Lamperti Isabella , Roberts-Borsani Guido W.
Published: December 2017

We introduce xCOLD GASS, a legacy survey providing a census of molecular gas in the local universe. Building on the original COLD GASS survey, we present here the full sample of 532 galaxies with CO (1–0) measurements from the IRAM 30 m telescope. The sample is mass-selected in the redshift interval

from the Sloan Digital Sky Survey (SDSS) and therefore representative of the local galaxy population with

. The CO (1–0) flux measurements are complemented by observations of the CO (2–1) line with both the IRAM 30 m and APEX telescopes, H i observations from Arecibo, and photometry from SDSS, WISE, and GALEX. Combining the IRAM and APEX data, we find that the ratio of CO (2–1) to CO (1–0) luminosity for integrated measurements is

, with no systematic variations across the sample. The CO (1–0) luminosity function is constructed and best fit with a Schechter function with parameters

,

, and

. With the sample now complete down to stellar masses of 109

, we are able to extend our study of gas scaling relations and confirm that both molecular gas fractions (

) and depletion timescale (

) vary with specific star formation rate (or offset from the star formation main sequence) much more strongly than they depend on stellar mass. Comparing the xCOLD GASS results with outputs from hydrodynamic and semianalytic models, we highlight the constraining power of cold gas scaling relations on models of galaxy formation.
Rectal Dieulafoy’s Lesion: An Underrecognized Cause of Lower Gastrointestinal Bleeding
Authors: Yagnik Vipul D.
Published: December 2017

Dieulafoy’s lesion is a rare but potentially a life-threatening condition. It accounts for 1%–2% of acute gastrointestinal (GI) bleeding. The lesion is most frequently located in the stomach and may be located anywhere in the alimentary tract. It can be present as severe GI bleeding or chronic GI blood loss. The cause of lesion remains uncertain. The range of clinical presentation varies from acute ill hospitalized patients as well as in the newborn.
Case of Cytomegalovirus Colitis in a Patient with Type 2 Diabetes Mellitus
Authors: Gupta Ankur , Jain Priyanka
Published: December 2017

Cytomegalovirus (CMV) colitis usually affects immunocompromised hosts. We report a patient with type 2 diabetes mellitus who presented with massive lower gastrointestinal bleed due to CMV colitis, which proved to be fatal. Awareness about this life-threatening entity is important in patients who have impaired immune response.
A Rare Case of Gastric Outlet Obstruction due to Large Intramural Duodenal Hematoma Following Endotherapy for Bleeding Duodenal Ulcer in a Patient with End-stage Renal Disease
Authors: Gupta Vineet Kumar , Soni Ram Chandra
Published: December 2017

We report a very rare case and probably the first from India of gastric outlet obstruction due to a large intramural duodenal hematoma following combination endotherapy with hemoclipping and injection adrenaline 1:10,000 for actively bleeding duodenal ulcer in an elderly male patient with diabetes, hypertension, and end.stage renal disease on maintenance hemodialysis. The patient improved to approximately 6 weeks of conservative treatment with nasojejunal feeding.
Successful Endoscopic Management of Bile Leak: A Single-Center Experience
Authors: Pawar Vinay , Sonthalia Nikhil , Pawar Sunil , Surude Ravindra , Contractor Qais , Rathi Pravin
Published: December 2017

Background and Aims: Bile leak is a rarely encountered complication most commonly occurring in the setting of biliary tract surgery. Site of leak may be from the gallbladder bed, the cystic duct, or rarely from injury to a major bile duct. Management has evolved with from radical surgery prevalent in earlier days to recent increased expertise in biliary endoscopy. This study aims to determine the impact of endoscopic management in treating symptomatic bile leak and discusses the role of surgery. Patients and Methods: In this retrospective study, patients with symptomatic bile leak admitted between 2012 and 2015 to the Department of Gastroenterology of a tertiary care center in Western India were analyzed. Site and extent of bile leak was evaluated using contrast enhanced computed tomography or magnetic resonance cholangiopancreatography. Endoscopic retrograde cholangiopancreatography (ERCP) was mainly used as a therapeutic tool rather than a diagnostic tool. ERCP was used as a primary mode of treatment wherever feasible. Percutaneous biliary drainage was used in technically difficult cases. Results: Twenty-seven patients with symptomatic bile leak were identified in aforesaid period. Bile leak in 21 (77.88%) patients was due to postlaparoscopic cholecystectomy injury, while in 6 (22.22%) patients, it was associated with liver abscess. Major bile duct injury was seen in 10 patients with postcholecystectomy status and in 5 patients with liver abscess. Out of 27 cases, 25 (92.59%) were treated with ERCP and 2 (7.40%) with percutaneous drainage. Surgery was not required in any of the patients. Sphincterotomy with stent placement for 6 weeks was effective in 23 (92%) patients, and only sphincterotomy was effective in 2 (8%) patients undergoing ERCP. There was no mortality due to bile leak. Conclusion: Most patients presenting with bile leak including major bile duct injury without complete bile duct transection can be successfully treated by endoscopic therapy without the need for surgery.
L’identification électronique des animaux
Authors: Ferrando Raymond
Published: December 2017

Le marquage classique pour l’identification des animaux domestiques et sauvages est à l’origine de nombreux inconvénients qui sont énumérés, en particulier les risques de transmission de maladies contagieuses. Le marquage électronique actuellement mis au point supprime les diverses anomalies et dangers des anciennes pratiques. Cette nouvelle technique est décrite.
El idioma de los argentinos: entre Borges y Bordelois
Authors: Stala Ewa
Published: December 2017

La inspiración de esta ponencia surgió del título de la conferencia (Entre Cervantes y Borges. Perspectivas y desafíos organizada en la Facultad de Filosofía y Letras de la Universidad de Ljubljana del 3 al 5 de noviembre de 2016), inquietudes anteriores (Stala, 2004, 2009, en prensa) y la lectura de otros trabajos (Agoff et al., 2013; Thon, 2010; di Tullio, 2011; Leśniak, 2014) sobre el español de la Argentina. Nuestra intención ha sido presentar las ideas principales acerca de esta variedad del idioma en su dimensión diacrónica: la idea ya histórica de Jorge Luis Borges y la contemporánea, de Ivonne Bordelois. Asimismo, estas divagaciones nos acercan a las preguntas de siempre: ¿qué es el idioma nacional? ¿para qué sirve? ¿qué lo ayuda y qué obstaculiza su desarrollo?
Énfasis y orden de palabras en algunas construcciones con vaya
Authors: Fernández Lorences Taresa
Published: December 2017

La forma del subjuntivo vaya se ha ido diversificando en español y ha dado lugar a unidades de distinta categoría y función, tal como muestran los ejemplos siguientes.
Un Borges tardío: la literatura, la memoria y el tiempo
Authors: Mancini Adriana
Published: December 2017

En el año 1978 a los 79 años, Borges dicta una serie de conferencias que fueron publicadas al año siguiente, en 1979, en una compilación cuyo título es Borges oral. Los temas, confiesa Borges en el prólogo a este libro, fueron aquellos temas que el tiempo le había consustanciado. En este sentido, podríamos pensar que las circunstancias en las que Borges dicta las conferencias y prologa este libro, coinciden con las que Adorno (2003) y Said (2009) definieron como características de lo que han dado en llamar un estilo tardío.
En busca de las huellas perdidas: dos lectores del Quijote del siglo XIX
Authors: Pregelj Barbara
Published: December 2017

En el prólogo a uno de los números de la revista Bukla su editor Samo Rugelj (2016: 3) llama la atención sobre la inversión en la que pueden convertirse los libros, sobre todo los libros antiguos. Parece que en estos tiempos en los que los libros valen bien poco un amante de libros, dispuesto a demostrar su amor por las letras con una inversión concreta, parece raro hasta tal punto de ser digno de alabanzas emitidas por el prologuista de la revista eslovena sobre novedades libreras.
Rosemeire Selma Monteiro-Plantin (org.) (2015): Certas palavras o vento não leva: Homenagem ao professor Antonio Pamies Bertrán.
Authors: Müller Pograjc Blažka
Published: December 2017

Nesta resenha, visa-se apresentar os conteúdos e a relevância do volume Certas palavras o vento não leva que a professora Rosemeire Selma Monteiro-Plantin, da Universidade Federal do Ceará, (Brasil), organizou em homenagem ao professor Antonio Pamies Bertrán, professor catedrático e titular do Departamento de Linguística Geral da Universidade de Granada, (Espanha).
Sejdalija Gušić, Edina Spahić, Cecilia Prenz Kopušar (eds.) (2015-2017): Laura Papo Bohoreta: rukopisi.
Authors: Šabec Maja
Published: December 2017

Entre 2015 y 2017, con el motivo del 450 aniversario de la llegada de los sefardíes a Bosnia, vino a sumarse a la cada vez más extensa bibliografía sobre los estudios sefardíes en el ámbito de los Balcanes una trilogía que sin duda gozará de buena acogida no solo en el círculo de los investigadores del tema sefardí en particular sino también entre los estudiosos de otras especialidades y el público lector local e internacional más amplio. Tres libros titulados Laura Papo Bohoreta: rukopisi [manuscritos] y publicados sucesivamente en 2015, 2016 y 2017 facilitan accesibilidad a la totalidad de los textos manuscritos de Laura Papo Bohoreta (1891-1941), la guardiana más distinguida de la cultura y la lengua de los sefardíes bosnios cuyo legado ha sido depositado, desde 1961, en el Archivo Histórico de Sarajevo.
A Julio Rodríguez Puértolas, maestro amado, y amigo entrañable de Verba Hispanica
Authors: Escalera Cordero Matías
Published: December 2017

A finales de septiembre de 2017, murió Julio Rodríguez Puértolas, mi maestro amado en la Universidad Autónoma de Madrid, allá por los años del final de la dictadura franquista y del comienzo de la Transición; y, luego, amigo, y referente entrañable para mí, hasta el final de sus días…
Anthropometric risk factors of cardiovascular disease in adult population of Dharan Municipality, Eastern Nepal: Gender and age differences
Authors: Shah S. , Koirala S. , Khanal L. , Koirala B.
Published: December 2017

Introduction: Cardiovascular diseases (CVD) besides cancer are the most serious threat to the health and life of the population of both developed and developing countries. The aim of the study was to know the gender and age differences with anthropometric CVD risk factors among Nepalese adults of Dharan Municipality. Materials and Methods: A population based cross-sectional study was conducted using a pretested self-administered structured questionnaire on anthropometric parameters which can affect CVD. A systematic random sampling technique was applied to cover the estimated 280 households with 900 adult population. The parameters of anthropometric risk factors for cardiovascular diseases were Body Mass Index (BMI), Waist Hip Ratio (WHR) and Body Fat Percentage (BFP). The result was expressed as mean ± SD. Independent student t test and ANOVA were applied to find out the gender and age differences respectively. “P” value of < 0.05 was considered to indicate statistical significance. Results: The mean and SD of BMI, WHR and BFP were found to be 24.17±4.13, 1.01±2.83 and 26.91±7.15 respectively. The gender differences of BFP were found to be statistically significant, whereas for BMI and WHR were not significant (p>0.05). The age differences in BMI and BFP were statistically significant (<0.05) whereas for WHR was not found to be significant (p>0.05). The signiicant positive correlations were found among these parameters (p< 0.01). Conclusion:The results of this study emphasize the need for a comprehensive study (both lipid and anthropometric) for providing baseline data to prevent CVD in eastern Nepal.
Writing Goes Back to School: Exploring the “Institutional Practice of Mystery” in a Graduate Education Program
Authors: Stooke Rosamund K , Hibbert Kathryn
Published: December 2017

Drawing on a qualitative case study of writing practices and pedagogies in one Canadian graduate Education program, this article discusses roles and responsibilities of course instructors for teaching and supporting academic writing at the master’s level. Data were collected through individual, semi-structured, in-depth interviews with 14 graduate students and eight professors and they were analyzed thematically. The discussion is framed by the academic literacies pedagogical framework (ACLITS). The data suggest that academic writing expectations can be sources of extreme stress for graduate students. The students and instructors lacked a common language to discuss student texts. In the absence of explicit academic writing pedagogies, students and instructors sometimes turned to simplistic advice received at school. The paper also discusses pedagogical challenges associated with the teaching of disciplinary writing genres in multi-perspectival fields such as Curriculum Studies.
Dans cet article, basé sur une étude de cas qualitative de pratiques et de pédagogies de rédaction menée dans un programme universitaire d’éducation de cycle supérieur dans une université canadienne, il est question des rôles et des responsabilités des instructeurs concernant l’enseignement et les travaux de rédaction universitaire de soutien au niveau de la maîtrise. Les données ont été recueillies à partir d’entrevues individuelles approfondies, semi structurées, auprès de 14 étudiants de cycle supérieur et de huit professeurs. Les entrevues ont ensuite été analysées de manière thématique. La discussion se place dans le cadre pédagogique des littéracies universitaires (ACLITS - Academic Literacies Pedagogical Framework). Les données suggèrent que les attentes en matière de travaux de rédaction universitaire peuvent être des sources de stress extrême pour les étudiants de cycle supérieur. Les étudiants et les instructeurs n’ont pas de langue commune pour discuter les textes produits par les étudiants. En l’absence de pédagogies explicites en matière de travaux de rédaction universitaire, les étudiants et les instructeurs se tournent parfois vers des avis simplistes obtenus à l’école. Cet article présente également les défis pédagogiques associés à l’enseignement des genres disciplinaires de travaux de rédaction dans des domaines qui présentent des perspectives multiples tels que les études du curriculum.
Relationships in the Flipped Classroom
Authors: McCollum Brett M , Fleming Cassidy L , Plotnikoff Kara M , Skagen Darlene N
Published: December 2017

This study examines the effectiveness of flipped classrooms in chemistry, and identifies relationships as a major factor impacting the success of flipped instruction methods. Examination of student interview data reveals factors that affect the development of peer-peer, peer-peer leader, and peer-expert relationships in first-year general chemistry and second-year organic chemistry flipped classrooms. Success was measured in terms of student perceptions of the effectiveness of the instruction, as well as student academic development. Furthermore, analysis of research participant interviews reveals that academic reading circles, open-response multiple-attempt group quizzes, and peer leaders are important elements of a text-centric flipped approach at a small-classroom, commuter-campus university. Student reflections and classroom observations provide further support for these conclusions.
Cet étude examine l’efficacité des salles de classe inversées en chimie et identifie la création de liens en tant que facteur important qui affecte la réussite des méthodes d’instruction inversée. L’examen des données provenant d’entrevues avec les étudiants révèle les facteurs qui affectent le développement des rapports d’étudiant à étudiant, d’étudiant à leader et d’étudiant à expert dans un cours inversé de chimie générale de première année et dans un cours de chimie organique de deuxième année. La réussite a été mesurée en termes de perceptions des étudiants de l’efficacité de l’instruction, ainsi que du développement académique des étudiants. De plus, l’analyse des entrevues des participants à la recherche révèle que les cercles de lecture universitaires, les tests de groupes à essais multiples et à réponses ouvertes, ainsi que les leaders de groupes sont des éléments importants d’une approche inversée centrée sur un texte en petite salle de classe, dans une université de banlieusards. Les réflexions des étudiants et les observations en salle de classe soutiennent également ces conclusions.
(RE)PLANEJANDO AULAS DE CIÊNCIAS: O CONTEXTO DE UM CENTRO DE ATENDIMENTO SOCIOEDUCATIVO DE GOIÂNIA
Authors: Santana Aline Neves Vieira , Shuvartz Marilda , Oliveira Neto José Firmino de
Published: December 2017

Este trabalho objetiva compreender como as aulas de Ciências são planejadas em um Centro de Atendimento Socioeducativo de Goiânia-GO, no qual se encontram adolescentes em conflito com a lei, privados e restritos de liberdade enquanto cumprem a medida socioeducativa de internação. Com o intento de abarcar e subsidiar a compreensão de elementos que partem da vida cotidiana dos participantes, percebe-se a necessidade de uma abordagem qualitativa nos moldes da pesquisa participante. Para a construção dos dados opta-se pela elaboração do planejamento das aulas de Ciências com a professora da instituição. Mediante a construção dos planos de aula concluiu-se que as intencionalidades educativas expressas no planejamento das aulas bem como no seu desenvolvimento possibilitam os caminhos para condução do aprendizado, logo, deve-se resgatar no planejamento pedagógico das aulas o compromisso com as novas maneiras de apreender e fazer Ciências, ampliando as vivências cidadãs, as quais são pouco empregadas no contexto da instituição escolar.
Comparison of MRI, CT, Dunn 45° and Dunn 90° alpha angle measurements in femoroacetabular impingement
Authors: Smith Kevin M. , Gerrie Brayden J. , McCulloch Patrick C. , Lintner David M. , Harris Joshua D.
Published: December 2017

Purpose:

To determine if a significant difference existed among alpha angle measurements between 4 imaging techniques, axial oblique CT and MRI, Dunn 45° and Dunn 90° plain radiographs, in patients with symptomatic cam femoroacetabular impingement (FAI) and labral tear.

Methods:

A single-surgeon prospective radiographic analysis of consecutive non-arthritic and non-dysplastic -patients with symptomatic FAI and labral tears who underwent surgery was performed. Alpha angle was measured using standard techniques as described by Nötzli. Cam morphology was defined via alpha angle measurement of >50.5 degrees. Group comparisons were made using ANOVA and chi-squared test. Sample size calculation was performed prior to study enrollment.

Results:

31 subjects (16 female; 33.5 ± 10.5 years mean age) were included. There was a significant difference in alpha angle measurements between all 4 imaging techniques (F [3,120] = 8.144; p<0.001), with the Dunn 45° view (66.3 ± 11.4°) significantly greater than all 3 other techniques (Dunn 90° [57.5 ± 10.7°; p = 0.015], MRI [53.3 ± 11.5°; p<0.001], and CT (54.9 ± 11.6°; p = 0.001). There was no significant difference in alpha angle between Dunn 90°, MRI, and CT. There was a significant difference in the observed number of hips with cam morphology between imaging techniques (χ2 9.4; p = 0.025).

Conclusions:

The Dunn 45° radiograph yielded a significantly higher alpha angle than Dunn 90°, axial oblique MRI, and CT imaging modalities. Use of the Dunn 90° or axial oblique MRI or CT as the threshold for cam osteoplasty may result in untreated symptomatic cam FAI. The authors recommend the Dunn 45° radiograph as the most sensitive evaluation of cam morphology.