bluuebunny/crossref_metadata_2025 huggingface dataset:
Egészségműveltség és alkoholfogyasztás összefüggésének vizsgálata szakgimnáziumban tanuló fiatalok körében
Authors: Tuza Alexandra , Barth Anita , Szőnyi Krisztina , Szőllősi Gergő József
Published: December 2021

A fiatalok alkoholfogyasztási szokásainak és egészségműveltségének vizsgálatát célzó nemzetközi kutatások rávilágítottak arra, hogy az alacsonyabb egészségműveltséggel rendelkező fiatalok körében gyakoribb az alkoholfogyasztás. Legjobb tudásunk szerint hazánkban még nem történt hasonló vizsgálat. A vizsgálat célja felmérni a 11. és 12. osztályos tanulók alkoholfogyasztási szokásait és egészségműveltségi szintjét, illetve ezek kapcsolatát megvizsgálni. A vizsgálatban összesen 120 fő vett részt. Kérdőívünk alkoholfogyasztási szokásokra vonatkozó kérdéseken túlmenően szocio-demográfiai kérdéseket is tartalmazott. Az egészségműveltségi szintet a Newest Vital Sign (NVS) kérdőív segítségével mértük. A kapott eredmények statisztikai elemzése és összefüggések feltárása Fisher-féle egzakt próbák segítségével, valamint Kruskal–Wallis tesztekkel valósult meg. Az NVS teszt alapján a vizsgálatban részt vevő fiatalok 45,83%-a nagy valószínűséggel megfelelő, 26,67%-a valószínűleg korlátozott, míg 27,50%-a nagy valószínűséggel korlátozott kategóriába került. Határérték szignifikanciát találtunk a lerészegedés teljes életprevalencia értéke és az egészségműveltségi szint között (p=0,057). A vizsgálatban részt vevő fiatalok igen magas a problémás egészségműveltségi szinttel rendelkezők aránya. Egyértelmű különbség azonban nem mutatható ki az egészségműveltség és az alkoholfogyasztási szokások között.
MRI- és UH-felvételek geometriai elemzése a beszédszintézisben
Authors: Trencsényi Réka
Published: December 2021

A gépi beszéd előállításának egyik új vonulata az artikulációs beszédszintézis, ami a hangképzéshez kapcsolódó vizuális információk feldolgozásán alapszik. A hangképző szervek statikus és dinamikus geometriai paramétereinek pontos ismerete alapvető szerepet játszik a beszédszintézis megvalósításában. Ezen adatok vizuális kinyerésének alkalmas forrásai lehetnek a beszéd közben készült MRI- és UH-felvételek, melyek különböző geometriával jellemezhetők. Az UH-keretek képpontjai egy polárkoordináta-rendszer kijelölésével kezelhetők a legkényelmesebben, míg az MRIkeretek képpontjainak leírásához egy descartes-i koordináta-rendszer adhat megfelelő kiindulópontot. Mivel az UH-felvételeken nem látható a nyelv hátsó része és a nyelvhegy, így az MRI-hez képest csak részleges információt kaphatunk a nyelv mozgásáról. Ennélfogva fontos és egyben nem triviális feladat az MRI- és UH-források geometriájának összehangolása. A publikációban bemutatom a geometriai transzformációk egy lehetséges módját.
Vagyok, aki vagyok. Kisebbségi csoportok identifikációja
Authors: Ladancsik Tibor , Maszlag Fanni
Published: December 2021

Az elmúlt fél évszázadban empirikusan is érzékelhető gyors változás és irányváltás ment végbe a társadalmi folyamatokban. Egyre interaktívabb lett világunk, gyorsabb lett az információáramlás, állandóan fejlődik a kommunikációs technológia. A felgyorsult folyamatok, a történelem és a kultúra alakulása a kisebbségi csoportokhoz tartozó családokban identitásválságot eredményezett. A tanulmány célja, hogy bemutassa, hogyan alakult a vajdasági vegyes házasságban élő párok és két magyarországi megyében élő roma női közösség tagjainak identifikációja, valamint milyen hasonlóságokat és különbségeket lehet felfedezni a két kisebbségi csoport életében. A kutatásunk során arra a következtetésre jutottunk, hogy a mobilitási csatornák megnyitása jelentősen gyorsítja az asszimilációt.
Az uszodai infrastruktúra vizsgálata az Észak-alföldi régióban
Authors: Kosztin Nikolett , Balatoni Ildikó
Published: December 2021

Az úszás azon közkedvelt sportágak egyike, amely amellett, hogy egészséget megőrző mozgásforma, bármely életkorban űzhető. Jelen társadalmunk jelentős hányadának fizikai inaktivitása miatt kutatók számos irányból vizsgálták, hogy miként lehetne rendszeres sportolásra bírni a lakosságot, többek között az épített környezet sportolási szokásokra gyakorolt hatásai is elemzésre kerültek. Kutatásunk során az Észak-alföldi régió 34 uszodáját tanulmányoztuk, telefonos interjú alapján végzett kérdőíves módszerrel. Áttekintettük az uszodák átadásának időpontjait, a létesítéskor megfogalmazott célokat, a medencék számát, hosszát. Elemeztük, hogy az egyes sportfoglalkozások, mint iskolai úszás, lakossági úszás, gyógytorna, edzés, versenyek hogyan jelennek meg az időbeosztásban, valamint, hogy a nyitva tartás miként befolyásolja a lakosság által történő igénybevétel lehetőségét. Megállapítható, hogy az érintett megyék egészségügyi mutatói alapján fontos lenne az egészséges életmódra nevelés, ehhez kapcsolódóan az úszás lehetőségének biztosítása is. Ugyanakkor a jelenleg rendelkezésre álló infrastruktúra kevés, emiatt az uszodaépítési program folytatása kiemelt jelentőségű.
Kisgyermekes édesanyák sportolási szokásai
Authors: Kosztin Nikolett , Balatoni Ildikó
Published: December 2021

A rendszeres fizikai aktivitás minden életkorban hasznos. A szülés utáni időszakban is számos jótékony hatása figyelhető meg a testmozgásnak, hiszen csökkenti a szorongást, javítja a hangulatot, hozzájárul a testsúly optimalizálásához és a fittségi állapot javításához. Kutatásunk során kisgyermekes édesanyák sportolási szokásainak változását vizsgáltuk a szülést megelőző állapothoz viszonyítva, külön elemezve a gyermek hat hónapos koráig illetve három éves koráig tartó, otthon töltött időintervallumot és a munkába visszatérés időszakát. A válaszadók egyharmada a szülést megelőzően sem sportolt, a kisgyermekkel otthon lévők további harmadának nincs rá ideje. A dolgozni visszatérő édesanyák 17,1% sportol legalább hetente egy alkalommal. Az anyasággal járó feladatok mellett a nők jelentős hányadának nem jut ideje saját magára. További kutatások lennének szükségesek a megoldási lehetőségek feltárására.
A fogyatékkal élők sportolási lehetőségei és motivációs tényezői
Authors: Varga Ábrahám , Balatoni Ildikó
Published: December 2021

Még a világ legfejlettebb részein is sok esetben komoly kihívás elé állíthat egy mozgásában vagy más módon korlátozott embert, ha speciális igényeinek megfelelő sportolási lehetősége(ke)t keres, különösen, ha lakóhelyéhez közel szeretne sportolni. Tekintettel arra, hogy mind a fogyatékossággal, mind az anélkül élő emberek esetében kiemelt jelentősége van (illetve jó néhány esetben csak lenne) az aktív életmódnak, valamint arra a sajnálatos tényre, hogy a rendelkezésre álló kutatási adatok alapján a parasportokat űzők aránya messze elmarad az ép sportolókétól, rendkívül hasznos lenne feltárni az e mögött meghúzódó okokat, felvázolni a politika által is minden további nélkül támogatható megoldásokat. Jelen tanulmány írása során azt a célt tűztük magunk elé, hogy az elmúlt 15 év fogyatékos sportolói motivációkat és lehetőségeket középpontba állító publikációnak áttekintése révén közelebb kerüljünk ennek a problémának a megoldásához, egyben egy olyan összefoglalását adjuk a témának, ami újabb kutatások kiindulópontjául szolgálhat.
The possible contexts of inclusion and special educational needs in the light of an international research
Authors: Fónai Mihály , Barnucz Nóra , Hüse Lajos
Published: December 2021

The relationship between school integration and special educational needs (hereinafter: SEN) is analyzed in the framework of an international resarch in this study. In the theoretical part the process of segregation, integration and inclusion is introduced, and also the use of the concepts is dicussed. The integration in the school system means the approach and practice against segregated education of students with disabilities with the aim to eliminate segregated education. SEN is not a diagnostic but an educational concept, and the its special pedagogy and legal term do not coincide. The research was extended to Ukrainian (the Transcarparthian n=280), Polish (n=271) and Hungarian students (n=552). The results show that school inclusion and social support are increased by school success. Success can increase the self-esteem of students with learning problems, which co-occures with the subjective perception of increasing social support and decreasing exclusion.
KIKLOPSKA SVAKODNEVICA ROMANA KIKLOP RANKA MARINKOVIĆA
Authors: Milanović Željko D.
Published: December 2021

U radu se istražuje svakodnevica predstavljena u romanu Kiklop Ranka Marinkovića. Dosadašnja istraživanja ovog romana bila su usmerena najčešće na isticanje izuzetnosti doživljaja glavnog junaka i zaobilazila su običnost svakodnevice u kojoj se odvija radnja. Insistiranjem na pomeranju svakodnevnih doživljaja iz običnosti u neobičnost mita ili razumevanjem svakodnevice kao karnevalskog vremena, iz istraživačkog fokusa nestaju ona značenja romana koja se više tiču mikropolitike pojedinca suprotstavljene makropolitici sveta. Razlikovanje mesta i nemesta u savremenoj antropologiji omogućava nam da otkrijemo nova značenja romana Kiklop koja se prvenstveno odnose na problematizovanje uticaja politike na život pojedinca kao i mogućnosti otpora tim politikama. U zaključku rada se kaže da Kiklop, kao jedan od umetnički najvrednijih romana hrvatske književnosti, ima svoje mesto i u razumevanju sadašnjosti jer i njene relacijski konstruisane prostore nastanjuju pojedinci kojima je neprekidno bekstvo jedina mogućnost da se oslobode straha.
Meningkatkan Kemampuan Fisik Motorik Halus Melalui Kegiatan Menganyam Dengan Bentuk Bahan Alam Pada Anak Kelompok A Di TK Pembina Amen Kecamatan Amen Kabupaten Lebong
Authors: Ningtyas Amanah Rahma
Published: December 2021

Dalam perkembangan anak, perkembangan motorik adalah perkembangan pengendalian gerak jasmani melalui kegiatan pusat syaraf, urat syaraf dan otot terkoordinasi. Perkembangan motorik seperti menggenggam,merangkak, duduk dan berjalan akan mendasari perkembangan lainnya yang lebih kompleks. Perkembangan fisik motorik anak dapat ditingkatkan melalui kegiatan mewarnai pola gambar seperti memberikan kebebasan pada anak untuk bereksplorasi dan beraktifitas sesuai perkembangan anak.mewarnai adalah kegiatan motorik halus anak yang harus dikembangkan sesuai perkembangan anak.Tujuan dan perbaikan kegiatan pengembangan kemampuan ini secara umum adalah untuk meningkatkan kemampuan motorik halus anak melalui kegiatan menganyam dengan bahan alam pada anak kelompok A di TK Pembina Amen Kec.Amen Kab.Lebong semester 1 tahun pelajaran 2020/2021. Subyek penelitian ini adalah anak–anak, pendidik,  Kepala Sekolah serta metode pembelajaran. Penelitian ini dilaksanakan pada semester 1 pada tanggal 10 Juni s/d 21 Juni 2020 di TK Pembina Amen Kecamatan Amen  Kabupaten Lebong. Adapun cara penelitiannya adalah menggunakan pelaksanaan perbaikan dua siklusya itusiklus I dan siklus II. Pada siklus I akan dibuat kegiatan yang seharusnya mampu dicapai anak. Pada siklus I dari RPPH 1-5 Presentase masih dibawah 85% Kurang berhasilnya rencana pembelajaran pada siklus I maka akan diadakan perbaikan pada siklus II. Siklus II setelah diadakan perbaikan presentase meningkat  jadi 93,3% semua disebabkan karna guru menggunakan metode  dan media pembelajaran yang sesuai karakteristik anak. Dalam penjabaran diatas dapat disimpulkan bahwa sebelum melaksanakan pembelajaran seorang guru harus mempersiapkan diri mulai dari media yang digunakan maupun metode yang harus dipakai , sehingga pada saat pembelajaran berlangsung guru dapat mengatasi masalah yang timbul di kelas. Guru juga harus pandai dalam mengkondisikan kelas sehingga pembelajaran berjalan dengan baik dan hasil yang dapat dicapai siswa dapat berkembang dengan optimal
A hazai kkv-k területi jellegzetességei válságok idején
Authors: Jeneiné Gerő Henriett Emese , Kincses Áron , Tóth Géza
Published: December 2021

A tanulmány néhány példa segítségével mutatja be az európai és a magyarországi mikro-, kis- és középvállalkozások (kkv) gazdasági jelentőségét a térségek felzárkóztatásában, képet ad alapvető jellemzőikről és helyzetükről. Feltárja a válságok hatásait a hazai kkv-kra, és azonosítja a válságok által leginkább érintett ágazatokat, valamint térségeket. A szerzők megvizsgálják a Magyarországon működő kkv-k területi jellegzetességeit, azok változásait, a 2008-as válság óta miként változott számuk, területi eloszlásuk, nettó árbevételük, bruttó hozzáadott értékük, foglalkoztatottaik létszáma, illetve mely térségek tekinthetők sérülékenynek a kkv-k szempontjából.
Latin American Integration Route and the state of Mato Grosso do Sul: productive characterization, threats, and possibilities of promotion
Authors: Boldrine Abrita Mateus , Amorim Souza Centurião Daniel , Rondina Neto Angelo , Vignandi Rafaella Stradiotto
Published: December 2021

The Latin American Integration Route (RILA) corresponds to the materialization of an old desire to integrate the peoples of South America. This route will connect important municipalities in Brazil, Paraguay, Argentina, and Chile. In the state of Mato Grosso do Sul (MS), it will connect important municipalities, and bring opportunities and threats. The objective of the study was to analyze the productive structure of the municipalities in Mato Grosso do Sul that will be directly affected by the RILA to better understand this process. For this purpose, we used an Exploratory Spatial Data Analysis (Spatial EDA) and the spatial Locational Quotient (sLQ) of the sectorial jobs of the municipalities of the State. The results point out a spatial inequality in productive sectors, delimiting "sectorial islands". In the industrial sector, the northeastern regions and the surroundings of the capital, Campo Grande, stand out. The northeast region of the State also stands out in the Civil Construction sector and, together with the north-central part of the MS, in the agriculture and livestock sector. In the trade sector, the southern region of the MS stands out, with proximity to Paraguay. In the services sector, there is a relative concentration in the capital and the extreme south of the State. In conclusion, we point out the urgent need for public policies to expand opportunities and mitigate the threats of integration managed by the route.
La Red Universitaria de la Ruta de Integración Latinoamericana (UniRila) y el Corredor Bioceánico: relaciones culturales entre Porto Murtinho/Brasil y Carmelo Peralta/Paraguay
Authors: Quintana Shiota Hanae Caroline , Akamine Mariana De Barros Casagranda , Chaia Alessandra , Santos Silva Érika , Dorsa Arlinda Cantero
Published: December 2021

La consolidación y la articulación entre universidades abre la posibilidad de un espacio privilegiado para discusiones, reflexiones y construcción de propuestas significativas de acciones académicas que posibiliten el trabajo técnico-científico interdisciplinario. La Red de Universidades en la Ruta de la Integración Latinoamericana (UniRila) fue creada en 2016, con el propósito de desarrollar acciones que apoyen los estudios de viabilidad del Corredor Bioceánico entre Brasil, Paraguay, Argentina y Chile. Este trabajo procura analizar la identidad y relación cultural entre Porto Murtinho-Brasil y Carmelo Peralta-Paraguay con vistas a las acciones de UniRila, enfatizando que la cultura se guió por principios y valores que sostienen el paradigma cultural de un pueblo en sus hábitos, creencias, valores e identidades, bien como la forma de difusión y conservación. La investigación utilizó el método deductivo con alcance sistémico mediante búsqueda bibliográfica y documental. Por tanto, para comprender mejor los temas relacionados con la cultura y los procesos de identidad, es necesario traer una breve noción de qué es la cultura y cuál es la relación cultural entre Porto Murtinho y Carmelo Peralta con vistas a la implementación del Corredor Bioceánico. Se infiere que la relación establecida conduce a la observación de que el entrelazamiento cultural estará en constante mutación o transformación a medida que se produzca la interacción e integración social.
Guaicuru caá, Cienfuegosia drummondii (A. Gray) Lewton, planta medicinal en el Chaco brasileño: conocimiento de la Ruta Bioceánica
Authors: Benites Maristela , Mamede Simone , Matias Rosemary , Albuquerque de Vargas Icléia
Published: December 2021

Guaicuru caá (Cienfuegosia drummondii) es una especie del Chaco que se usa frecuentemente como planta medicinal en Porto Murtinho, Mato Grosso do Sul, Brasil y en otras regiones del Chaco sudamericano. El objetivo de este trabajo fue realizar el análisis fitoquímico de C. drummondii, con el fin de determinar las principales clases de sustancias químicas presentes en el extracto de hoja y describir las principales formas de uso y aplicación medicinal de esta planta por la población de Porto Murtinho, Mato Grosso do Sul, desde la perspectiva de la etnobotánica y del desarrollo local sostenible. La planta fue recolectada en la zona rural del municipio, en octubre de 2017, y los análisis se realizaron en el laboratorio. Las principales clases de metabolismo secundario encontradas en el extracto etanólico de las hojas de C. drummondii correspondieron a compuestos fenólicos, flavonoides y antraquinonas, estos últimos con 100% de frecuencia. Todavía hay una falta de estudios fitoquímicos y farmacológicos de plantas del Chaco brasileño, muchas de las cuales son comúnmente utilizadas como hierbas medicinales por las comunidades locales. Por tanto, la valorización y protagonismo de diferentes prácticas culturales no hegemónicas, como las vinculadas a la etnobotánica y la etnociencia en general, pueden atribuir un valor superlativo al turismo cultural y propuestas de desarrollo en la ansiada Ruta de la Integración Latinoamericana.
La Ruta Bioceánica como campo de discursividades producidas
Authors: Andrade Asato Thiago , Dorsa Arlinda Cantero , Fittipaldi Gonçalves D´ébora , Mariani Milton
Published: December 2021

Este artículo es parte del producto de una tesis titulada “La Ruta Bioceánica como campo de posibilidades para el desarrollo de la actividad turística”. Se enfoca en la posibilidad de abrir una Ruta de Integración entre países sudamericanos orientada al desarrollo en sus diferentes interfaces en los respectivos países que conforman el llamado Corredor Bioceánico, a saber: Brasil, Paraguay, Argentina y Chile. La designación de "Ruta de Integración" otorga más legitimidad, incluso en el sentido literal de la palabra "integración", abriendo más posibilidades de desarrollo, interconectando otras ciudades que se beneficiarán de manera inductiva, haciendo más el desarrollo de Mato Grosso do Sul. uniforme. Esta ruta que atraviesa la Ruta Bioceánica y, en consecuencia, el Corredor Vial Bioceánico puede brindar oportunidades para un cambio de perspectiva local, principalmente por las inversiones realizadas en infraestructura de todo tipo en la zona fronteriza que comprende Porto Murtinho y Carmelo Peralta, valorando el colectivo interés de las comunidades locales. Las fuentes teóricas establecen una confluencia de campos disciplinares a medida que se discute el conocimiento del campo del conocimiento en Análisis del Discurso desde diferentes enfoques, contextualizando los caminos necesarios para definir las categorías analíticas que fueron seleccionadas para el análisis de percepciones elegidas.
Magnitude of tuberculosis on the Bioceanic Route: an epidemiological description
Authors: Arantes da Cunha João Pedro , Vilela de Campos Rafael , Maciel Ruberval Franco , Campos Marques Ana Maria
Published: December 2021

This study aims to assess the epidemiological situation of five municipalities that are part of the bioceanic route in order to analyze the descriptors and general health aspect of the population through a retrospective, quantitative and cross-sectional descriptive study with a documentary approach, from secondary data reported to the National System of Notifiable Diseases in the municipalities of Guia Lopes da Laguna, Jardim, Nioaque, Porto Murtinho, Sidrolândia and Campo Grande, in the state of Mato Grosso do Sul, in the period from January 2015 to December 2020. The incidence rate ranged between 32.23 and 79.4 cases/100,000 inhabitants. There was a predominance of individuals aged between 30-39 years (26.05%) and males (67.5%). The most important injuries were alcoholism (19.15%) and smoking (18%). In the exams, 52.3% had positive bacilloscopy and 32.03% had a positive culture. The incidence of tuberculosis in the evaluated municipalities was higher than the Brazilian average and that of the state of Mato Grosso do Sul. These evaluated municipalities do not have a favorable epidemiological situation with regard to tuberculosis and the construction of the biocenic route may further aggravate the situation.
Kegagalan Inovasi Pertamina Dalam Mengembangkan Rantai Supply Pemasaran Dan Ketergantungan Terhadap Impor BBM Produksi Kilang Minyak Singapura
Authors: Wuryandari Ratna Dewi
Published: December 2021

AbstrakInovasi seringkali menjadi tuntutan penting dalam mendukung sebuah terobosan perubahan yang akan berdampak pada nilai tambah perusahaan dan negara. Melalui inovasi sumber daya alam, maka diharapkan dapat menciptakan sumber daya produksi baru maupun pengolahan sumber daya. Namun demikian, sebuah inovasi yang pada awalnya dibangun sebagai terobosan pada akhirnya seringkali menyimpang pada pelaksanaan akibat system yang kompleks dan terkait dengan kepentingan praktis dari sekelompok golongan. Penulisan ini menggunakan studi kasus Pertamina Energy Trading Limited/Petral dalam kegagalan inovasi yang dilakukan untuk mengembangkan rantai supply pemasaran serta terkait ketergantungan Pertamina terhadap impor BBM produksi kilang minyak Singapura. Hasil penelusuran penulisan menyimpulkan, budaya merupakan fondasi mendasar dalam pemerintahan yang mendasari dalam berbagai bidang serta terobosan-terobosan yang dilakukan oleh Pemerintah. Dari kegagalan Pertamina melalui Petral kita dapat belajar, dimana budaya dan kepemimpinan transformasional merupakan factor kunci yang akan membawa perubahan dan pengembangan inovasi dalam berbagai bidang di Indonesia.
Department of Theoretical Electrical Engineering KPI. Igor Sikorsky years, people, destiny
Authors: Spinul L. , Chibelis V. , Lobodzinsky V. , Svyatnenko V.
Published: December 2021

The article offered to the reader is devoted to the formation and stages of development of one of the oldest departments of Kyiv Polytechnic Institute - Department of theoretical electrical engineering. An excerpt from the KPI personnel is given, which confirms the date of foundation . The history of the department is presented through its heads and their activities - from the day of formation to the present time. Main scientific directions of the department's activity and its achievements are given. The article will be useful for the heads and scientific and pedagogical staff of Ukrainian universities, a wide range of readers who are not indifferent to the history of education and science in Ukraine.
PRECEDENT-ANALYTICAL MODEL OF EXERCISE SYSTEM FOR ENERGY MANAGERS
Authors: Pleskach B. , Samoilov V. , Prokopenko V. , Zakladnyi O.
Published: December 2021

The topical issue of development of theoretical bases of creation and application of computerized systems for training of energy managers of industrial enterprises is considered. The object of the study is the practical activities of the company's staff, aimed at improving the energy efficiency of production systems for various purposes. The subject of research is computer technologies of training and coaching of industrial enterprise personnel. The purpose of the study is to create tools aimed at training the staff of energy management services. The research is based on scenario modeling of energy manager actions and precedent modeling of equipment reactions to such actions. The modeling of energy manager actions is based on the Deming cycle, and the modeling of reactions of production systems is based on cases of quasi-stationary energy consumption of the technological system. The software platform of the proposed technology consists of software modules that reproduce the control cycle PDCA (Plan-Do-Check-Act) and the subject area of ​​training in the form of a software add-on. The technology allows to work out the actions of the energy manager aimed at planning energy saving measures and calculating the financial and economic results achieved during their implementation.
SELECTION AND CALCULATION OF STEPPER MOTORS FOR CNC
Authors: Reytskiy M. , Kovalenko M. , Tymoshchuk O.
Published: December 2021

Today, modern technologies tend to develop rapidly. The application of advanced inventions, principles, systems and approaches allows to simplify the production process, reduce the cost of manufacturing finished products, replace monotonous manual work with automated systems and devices. The basis of the power drive of such systems are electric motors: with permanent magnets, direct current, stepper, etc. When developing any electromechanical system, the task of choosing the type of drive motor, its parameters and characteristics. This article is devoted to the choice of such an electric motor for an electromechanical system for three-dimensional plastic printing. As a result of comparative analysis of parameters and characteristics of different types of motors, it is established that bipolar stepper motors are optimal for use in low-power and small-sized systems for three-dimensional printing. This is due to the simplicity of their design, reliability and low requirements for nominal and maximum torque.
FORECAST EVALUATION OF HEAT PROTECTION AND MECHANICAL PROPERTIES OF INSULATING CONSTRUCTION CERAMIC MATERIALS
Authors: Shchukina Liudmyla Pavlivna , Halushka Yaroslav Olegovych , Yashchenko Larysa Oleksanrivna , Lihezin Stanislav Leonidovych
Published: December 2021

An integrated approach to determine the rational design of wall ceramic products based on modeling their behavior under operating conditions is proposed. This approach was used in the development of technology for heat–efficient insulating construction ceramic materials for energy–saving construction. For two models of porous–hollow ceramic products with a porous frame (40 % of voids) and a dense frame (60 % of voids), a predictive assessment of their heat–shielding and mechanical properties was carried out. Calculations of the equivalent coefficient of thermal conductivity of models based on Fourier’s law established that with a decrease in the voidness of products with a porous wall, the coefficient of their thermal conductivity decreases by 12 %, which improves the heat–shielding properties. Based on the results of computer simulation of the behavior of models under the influence of static power loads, it was determined that porosity of the ceramic framework of products leads to degradation of mechanical strength almost proportionally to a decrease in voidness. The stress–strain state of 3D models of ceramic structures with different pore geometry (spherical, globular, ellipsoidal) is analyzed and it is shown that stresses are concentrated in the contact zones of a ceramic matrix with pores. It is shown that the most durable is the structural model with spherical pores. The expediency of organizing such a structure, the need to strengthen the ceramic matrix of materials and zones surrounding the pores, as the most vulnerable structural sites, is shown. The results of predictive calculations have been experimentally confirmed in the development of technology for structural and heat–insulating composite–type ceramic materials based on low–melting loam and ash microspheres, which provide a given structural picture of the ceramic material.
Protocol for applying Machine Learning models for the transformation of conventional fluorescence images to super-resolution
Authors: Zinchuk Vadim , Grossenbacher-Zinchuk Olga
Published: December 2021

Machine Learning offers the opportunity to visualize the invisible in conventional fluorescence microscopy images by improving their resolution while preserving and enhancing image details. This protocol describes the application of GAN-based Machine Learning models to transform the resolution of conventional fluorescence microscopy images to a resolution comparable with super-resolution. It provides a flexible environment using a modern app functioning on both desktop and mobile computers. This approach can be extended for use on other types of microscopy images empowering life science researchers with modern analytical tools.
Qingre Huoxue Decoction, A Traditional Chinese Herbal Formulation, Impacts Angiogenesis in Psoriasis-Like Skin Through the HIF-1α/Flt-1/VEGF Pathway
Authors: Li Wen , He Xiang , Zhu Jiong , Zhang Huimin
Published: December 2021

Background: Qingre Huoxue Decoction (QHD), a traditional Chinese medicine (TCM) formulation, could alleviate psoriasis in our previous studies. The present work aimed to assess QHD’s effects on psoriasis and the underpinning mechanism in cultured cells and experimental animals.Methods: The CCK-8 assay was carried out for cell viability assessment. HUVEC migration was assessed by transwell and wound healing assays. QHD-induced suppression of capillary tube formation in HUVECs was detected by tube formation assay. In addition, the imiquimod (IMQ)-induced male BALB/c mouse model of psoriasis was established to examine the Psoriasis Area and Severity Index (PASI) after QHD administration. HIF-1α, Flt-1 and VEGF expression levels in vivo were assessed by immunoblot, qPCR and immunofluorescence. Results: The results showed that QHD dose-dependently reduced viability in HUVECs. In addition, QHD suppressed tube formation in HUVECs at levels below those needed to inhibit HUVECs. Upon QHD administration, HUVEC migration was markedly decreased; QHD effectively prevented the migratory ability of HUVECs, as determined by wound areas at 0h, 12h and 24h, respectively. Finally, QHD starkly downregulated HIF-1α, Flt-1 and VEGF in the IMQ-induced mouse model, at the protein and mRNA levels.Conclusions: In summary, QHD inhibits angiogenesis in cultured cells and mice. HIF-1α/Flt-1/VEGF signaling is important in angiogenesis and psoriasis development. These findings provide a rationale for developing QHD for clinical use against psoriasis.
Availability And Readiness of Healthcare Facilities And Their Effects On Long-Acting Modern Contraception Use In Bangladesh: Analysis of Linked Data
Authors: Khan Md Nuruzzaman , Islam M Mofizul , Akter Shahinoor
Published: December 2021

Aim: Evidence on the availability and accessibility of health facilities and their impacts on long-acting modern contraceptives (LAMC) use in low- and middle-Income countries are scarce. This study examined the influence of the availability and readiness of health facilities in determining the use of LAMC in Bangladesh.Methods: We linked data of the Bangladesh Demographic and Health Survey and the Health Facility Survey using the administrative-boundary linkage method. Mixed effect multilevel logistic regression was conducted. The sample comprised 10,938 married women of 15-49 years of age, who were fertile but did not desire a child within two years of the date of survey. The outcome variable was the current use of LAMC (yes, no) and the explanatory variables were health facility-, individual-, household- and community-level factors.Results: Nearly 34% of participants used LAMC with significant variations across areas in Bangladesh. The average distance between the nearest LAMC-providing health facilities and women’s homes was 6.36 km, higher in the Sylhet division (8.34 km) and lower in the Dhaka division (4.34 km). Increased scores for the management (adjusted odds ratio (AOR) 1.59; 95% CI, 1.21-2.42) and infrastructure (AOR, 1.44; 95% CI, 1.01-1.69) of health facilities were positively associated with the overall uptake of LAMC. AORs for women to report using LMAC were 2.16 (95% CI, 1.18-3.21) and 1.74 (95% CI, 1.15-3.20), respectively, for per unit increase in the availability and readiness scores to provide LAMC at the nearest health facilities. Nearly 27% decline in the likelihood of LAMC uptake was observed for every kilometer increase in the average regional-level distance between women’s homes and the nearest health facilities.Conclusion: The availability of health facilities close to residence and their improved management, infrastructure, and readiness to provide LAMC play a significant role in increasing LAMC uptake among women. Policies and programs should prioritize increasing the availability and accessibility of health facilities that provide LAMC services.
Melatonin Ameliorates Developmental Landmarks Induced by Gestational and Lactational Coexposure to Chlorpyriphos and Cypermethrin in F1 Male Rats
Authors: Shittu Muftau , Ambali Suleiman , Ayo Joseph , Kawu Umaru , Akande Motunrayo
Published: December 2021

The ameliorative potentials of melatonin (ML) on developmental changes evoked by gestational and lactational co-exposure to chlorpyriphos (CP) and cypermethrin (CY) was investigated in male Wistar rats. Pregnant dams were divided at random into 6 groups of 10 animals each and treated orally by gavage from gestation day 1 to postnatal day 21 with the following regimens: The DW, SO and ML groups were administered distilled water (2 ml/kg), soya oil (2 ml/kg) and melatonin (0.5 mg/kg), respectively; CC group was co-administered CP (1.9 mg/kg) and CY (7.5 mg/kg); MC group was pretreated with ML (0.5 mg/kg) and followed by co-administration of CP and CY while the CM group was administered CP and CY and then treated with ML. We evaluated the developmental parameters on the F1 generation male rats at different postnatal intervals following parturition. Alterations in litter size and weight, number of live/dead pups, anogenital distance, crown-rump length, time of eye and ear openings, and testicular descent induced by gestational and lactational exposure to CP and CY in F1 male rats were mitigated by pre- and post-administration of ML. These curative and prophylactic potentials of ML may be partly attributed to its widely known antioxidant property.
Rapid Shear Stress-dependent ENaC Membrane Insertion is Mediated by the Endothelial Glycocalyx and the Mineralocorticoid Receptor
Authors: Cosgun Zülfü C. , Sternak Magdalena , Fels Benedikt , Bar Anna , Kwiatkowski Grzegorz , Pacia Marta Z. , Herrnböck Lisbeth , Lindemann Martina , Stegbauer Johannes , Höges Sascha , Chlopicki Stefan , Kusche-Vihrog Kristina
Published: December 2021

The contribution of the shear-stress sensitive epithelial Na+ channel (ENaC) to the mechanical properties of the endothelial cell surface under (patho)physiological conditions is unclear. This issue was addressed in in vivo and in vitro models for endothelial dysfunction.
Cultured human umbilical vein endothelial cells (HUVEC) were exposed to laminar (LSS) or non-laminar shear stress (NLSS). ENaC membrane insertion was quantified using Quantum-dot-based immunofluorescence staining and the mechanical properties of the cell surface were probed with the Atomic Force Microscope (AFM) in vitro and ex vivo in isolated aortae of C57BL/6 and ApoE/LDLR-/- mice. Flow- and acetylcholine-mediated vasodilation were measured in vivo using magnetic resonance imaging.
Acute LSS led to a rapid mineralocorticoid receptor (MR)-dependent membrane insertion of ENaC and subsequent stiffening of the endothelial cortex caused by actin polymerization. Of note, NLSS stress further augmented the cortical stiffness of the cells. These effects strongly depend on the presence of the endothelial glycocalyx (eGC) and could be prevented by functional inhibition of ENaC and MR in vitro and ex vivo endothelial cells derived from C57BL/6 and ApoE/LDLR-/- vessel. As expected, in vivo in C57BL/6 vessels ENaC- and MR-inhibtion blunted flow- and acetylcholine-mediated vasodilation, while in the dysfunctional ApoE/LDLR-/- vessels this effect was absent.
In conclusion, under physiological conditions, endothelial ENaC, together with the glycocalyx, was identified as an important shear stress sensor and mediator of endothelium-dependent vasodilation. In contrast, in pathophysiological conditions, ENaC-mediated mechanotransduction and endothelium-dependent vasodilation were lost, contributing to sustained endothelial stiffening and dysfunction.
The role of environmental regulation, industrial upgrading and resource allocation on foreign direct investment: Evidence from 276 Chinese cities
Authors: Qiu Wei , Bian Yaojun , Zhang Jinwei , Irfan Muhammad
Published: December 2021

Environmental pollution is becoming more and more prevalent in China, accompanied by the excessive expansion of the country's foreign direct investment in the scale of resource-based industries. This article uses the panel data of 276 prefecture-level cities in China from 2003 to 2016 to estimate the impact of environmental regulation on foreign direct investment by employing the Spatial Durbin model. The empirical results show that: firstly, environmental regulation, and foreign direct investment have an obvious spatial correlation. Secondly, environmental regulation significantly inhibits foreign direct investment and has significant negative space spillover. Thirdly, non-eastern cities' environmental regulation has significantly greater inhibitory effects on foreign direct investment than eastern cities, and the key cities' environmental regulation has greater inhibitory effects than ordinary cities. Finally, from the perspective of industrial upgrading and resource configuration, environmental regulation has significantly promoted foreign direct investment and have significant negative space spillovers. Therefore, the reasonable use of environmental regulatory measures through industrial upgrading and resource configuration to attract clean, capital-intensive and technology-intensive enterprises and to achieve the effect of "decontamination and clean" for foreign-funded enterprises is critical.
Combining Ability and Gene Action for Yield Improvement in Kenaf (Hibiscus Cannabinus L.) Under Tropical Conditions Through Diallel Mating Design
Authors: Al-Mamun Md , MOHD. RAFII Y. , AZIZAH MISRAN , ZULKARAMI BERAHIM , ZAITON AHMAD , HA KHAN MD MAHMUDUL , YUSUFF OLADOSU
Published: December 2021

Nine morphologically distinct kenaf genotypes were hybridized to produce 36 hybrids following a half diallel mating design. The combining ability and gene action of 15 yield and yield components were assessed in hybrids and their parents across two environments. Except for the mid diameter and plant height traits, there were highly significant differences (p ≤ 0.01) between both the analysis of variance of environments and the interaction of genotype and environment. For the inheritance of these traits, additive gene effects were considerable, and the expression of these additive genes was heavily influenced by the environment. Significant differences were found for all studied traits for GCA except top diameter, and SCA except plant height and top diameter, implying the presence of both additive and non-additive gene action for the inheritance of the concerned characters. For all features except top diameter and number of nodes, the magnitude of GCA variation was significantly higher than that of SCA variance, indicating the additive gene's predominance. The parental lines P1, P3 and P4 were determined to be outstanding general combiners for fibre yield and yield-related parameters. Considering combining ability and genetic analysis study together, the crosses P1 × P4, P1 × P9, P2 × P3, P2 × P5, P4 × P6, P4 × P7, P4 × P9, P5 × P8, and P7 × P9 were found promising for their heterotic response to higher fibre yield, stick yield, seed yield and and could be useful by adopting proper strategies for future improvement in kenaf breeding programmes.
Relationship Between Smoking, Narcissism, and Impulsiveness Among Young Women
Authors: Kertzman Semion , Kagan Alex , Vainder Michael , Lapidus Rina , Weizman Abraham
Published: December 2021

Although the connection between smoking and individual differences has been recently recognized, the relationship between narcissistic personality traits and cigarette smoking has received less attention. The notion that personality traits can be associated with addictive behavior is influential in clinical practice. However, questions remain about specific interactions between smoking and personality characteristics that need empirical support to substantiate this hypothesis. This study thus identifies narcissistic and impulsive personality traits as precursors of smoking in a sample of tattooed individuals. In a cross-sectional study (N = 120), personality traits were assessed in young women (aged 18-35 years) using the Narcissistic Personality Inventory (NPI) and the Barratt Impulsivity Scale (BIS-11). The current study, using the regression analysis, has clearly demonstrated that young women who smoke have different personality characteristics as compared with women who do not smoke.
Umbilical Cord Thrombosis: A Rare but Life-threatening Occurrence
Authors: Tong Long-xia , Xiao Ping , Xie Dan , Wu Lin
Published: December 2021

Background: Thrombosis of umbilical vessels is a rare but life-threatening pregnancy complication. The correct diagnosis and clinical management of umbilical cord thrombosis remain a challenge. This study aimed to evaluate the meaningful clinical manifestations and features of umbilical cord thrombosis and its optimal management options.Methods: This retrospective study analyzed umbilical cord thrombosis cases enrolled from January 1, 2011, to May 31, 2021. Data were collected from medical archives where the diagnoses of all patients were established by histopathology.Results: A total of 66 patients with umbilical cord thrombosis were enrolled, including 20 patients with intrauterine fetal death and 6 with fatal labor induction in the second trimester. The overall incidence of umbilical cord thrombosis was 0.05% (66/123,746), and the incidence increased significantly in the last 2 years, reaching 0.19% in 2021. The chief complaint was decreased fetal movement (25/60) or nonreactive nonstress test (NST) (19/40). In the 20 patients with intrauterine stillbirth, 8 patients had ignored fetal movement and were referred to the hospital because of ultrasound findings of intrauterine stillbirth. Five patients were misdiagnosed with a single umbilical artery on prenatal ultrasound. Twenty patients underwent emergency cesarean section due to decreased fetal movement and unresponsive fetal monitoring; all neonates were alive. The gross examination of the placenta and cord revealed umbilical cord abnormalities in 26 patients (39.4%, 26/66). The pathological examination revealed venous, venous and arterial, and arterial thrombosis in 74.2%, 12.1%, and 13.6% of patients, respectively.Conclusions: The main manifestation of umbilical cord thrombosis was decreased or disappeared fetal movement. The importance of self-counting fetal movement should be emphasized to patients. The abnormalities in the umbilical cord are the main cause of this phenomenon. Focus on counting fetal movements, electronic fetal monitoring, and specific signs during a prenatal ultrasound can help early identification of umbilical cord thrombi. Emergency cesarean section is recommended to reduce the risk of interrupting the umbilical cord blood flow.
De novo variants in Chinese ASD trios reveal distinct genetic basis underlying autism with and without developmental delay
Authors: Wang Jincheng , Yu Juehua , Wang Mengdi , Zhang Lingli , Yang Kan , Du Xiujuan , Wu Jinyu , Wang Xiaoqun , Li Fei , Qiu Zilong
Published: December 2021

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder causing impairments in social communication and stereotypical behaviors, often with developmental delay or intellectual disabilities (DD/ID). Accruing evidence indicates that ASD is highly heritable and genome-wide studies on ASD cohorts have defined numerous genetic contributors. Notably, since most of these studies have been performed with individuals of European and Hispanic ancestries, thus there is a paucity of genetic analyses of ASD in the East Asian population. Here, we performed whole-exome sequencing on 772 Chinese ASD trios, combining with a previous 369 ASD trios, to identify de novo variants in 1141 ASD trios. We found that ASD without DD/ID carried less disruptive de novo variants than ASD with DD/ID. Surprisingly, we found that expression of genes with de novo variants in ASD without DD/ID were enriched in a subtype of human neural progenitor cells. Importantly, some ASD risk genes identified in this study are not present in the current ASD gene database, suggesting that there may be unique genetic contributors to ASD with the East Asian ancestry. We validated one such novel ASD candidate gene – SLC35G1 by showing that mice harboring heterozygous deletion of Slc35g1 exhibited defects in social interaction behaviors. Together, this work nominates novel ASD candidate genes and suggests that genome-wide genetic studies in ASD cohorts of different ancestries are essential to reveal the comprehensive genetic architecture of ASD.
New Records of Neobenedenia Girellae (Hargis, 1955) (Monogenea: Capsalidae) In Marine Ornamental Fish Imported To Yucatan, Mexico
Authors: Paredes-Trujillo Amelia , Vidal-Martínez Victor Manuel , Hernández David , Gonzalez-Solis David , Río-Rodríguez Rodolfo del
Published: December 2021

We detected N. girellae infections in 40 species belonging to 12 families of imported marine ornamental fish from a public aquarium in the Mexican state of Yucatan in January 2018 to December 2020 and carried out their identification to the species level using morphological and molecular analyses. Monogeneans were corroborated morphologically and molecularly using a partial sequence of 28S (region D1–D3) ribosomal DNA and analyzed in a molecular phylogenetic context in combination with data derived from other species of N. girellae available in GenBank. The phylogenetic tree revealed that the specimen found consistently belonged to the N. girellae clade. High infection parameters were detected of N. girellae in the hosts. This identification is relevant to aquarists and aquaculturists in the Gulf of Mexico because N. girellae is considered highly pathogenic in confined fish. Clearly, this work demonstrates that the importation of ornamental fish, coupled with deficient sanitary measures (lack of quarantine areas in distribution centres) contributes to the introduction of parasites and their establishment and dispersal within Mexico.
Interleukin-6 and Granulocyte colony-stimulating factor as predictors of the prognosis of influenza-associated pneumonia
Authors: Zhang Jiaying , Wang Jingxia , Gong Yiwen , Gu Yudan , Xiang Qiangqiang , Tang Ling-Ling
Published: December 2021

Background: Pneumonia is a common complication of influenza and closely related to mortality in influenza patients. The present study examines cytokines as predictors of the prognosis of influenza-associated pneumonia. Methods: This study included 101 inpatients with influenza (64 pneumonia and 37 non-pneumonia patients). 48 cytokines were detected in the serum samples of the patients and the clinical characteristics were analyzed. The correlation between them was analyzed to identify predictive biomarkers for the prognosis of influenza-associated pneumonia.Results: Seventeen patients had poor prognosis and developed pneumonia. Among patients with influenza-associated pneumonia, the levels of 8 cytokines were significantly higher in those who had a poor prognosis: interleukin-6 (IL-6), interferon-γ (IFN-γ), granulocyte colony-stimulating factor (G-CSF), monocyte colony-stimulating factor (M-CSF), monocyte chemoattractant protein-1 (MCP-1), monocyte chemoattractant protein-3, Interleukin-2 receptor subunit alpha and Hepatocyte growth factor. Correlation analysis showed that the IL-6, G-CSF, M-CSF, IFN-γ, and MCP-1 levels had positive correlations with the severity of pneumonia. IL-6 and G-CSF showed a strong and positive correlation with poor prognosis in influenza-associated pneumonia patients. The combined effect of the two cytokines resulted in the largest area (0.926) under the receiver-operating characteristic curve. Conclusion: The results indicate that the probability of poor prognosis in influenza patients with pneumonia is significantly increased. IL-6, G-CSF, M-CSF, IFN-γ, and MCP-1 levels had a positive correlation with the severity of pneumonia. Importantly, IL-6 and G-CSF were identified as significant predictors of the severity of influenza-associated pneumonia.