bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparative Study on Delivery of Externally Attached DNA by Papillomavirus VLPs and Pseudoviruses
Authors: Brendle Sarah , Cladel Nancy , Balogh Karla , Alam Samina , Christensen Neil , Meyers Craig , Hu Jiafen
Published: December 2021

Human papillomavirus (HPV) 16 capsids have been chosen as a DNA delivery vehicle in many studies. Our preliminary studies suggest that HPV58 capsids could be better vehicles than HPV16 capsids to deliver encapsidated DNA in vitro and in vivo. In the current study, we compared HPV16, HPV58, and the cottontail rabbit papillomavirus (CRPV) capsids either as L1/L2 VLPs or pseudoviruses (PSVs) to deliver externally attached GFP-expressing DNA. Both rabbit and human cells were used to test whether there was a species-specific effect. DNA delivery efficiency was determined by quantifying either GFP-expressing cell populations or mean fluorescent intensities (MFI) by flow cytometry. Interestingly, CRPV and 58-VLPs and PSVs were significantly more efficient at delivering attached DNA when compared to 16-VLPs and PSVs. A capsid/DNA ratio of 2:1 showed the highest efficiency for delivering external DNA. The PSVs with papillomavirus DNA genomes also showed higher efficiency than those with irrelevant plasmid DNA. HPV16L1/58L2 hybrid VLPs displayed increased efficiency compared to HPV58L1/16L2 VLPs, suggesting that L2 may play a critical role in the delivery of attached DNA. Additionally, we demonstrated that VLPs increased in vivo infectivity of CRPV DNA in rabbits. We conclude that choosing CRPV or 58 capsids to deliver external DNA could improve DNA uptake in in vitro and in vivo models.
mRNA COVID-19 Vaccines and Long-Lived Plasma Cells: A Complicated Relationship
Authors: Giannotta Girolamo , Giannotta Nicola
Published: December 2021

mRNA COVID-19 vaccines have hegemonized the world market, and their administration to the population promises to stop the pandemic. However, the waning of the humoral immune response, which does not seem to last so many months after the completion of the vaccination program, has led us to study the molecular immunological mechanisms of waning immunity in the case of mRNA COVID-19 vaccines. We consulted the published scientific literature and from the few articles we found, we were convinced that there is an immunological memory problem after vaccination. Although mRNA vaccines have been demonstrated to induce antigen-specific memory B cells (MBCs) in the human population, there is no evidence that these vaccines induce the production of long-lived plasma cells (LLPCs), in a SARS-CoV-2 virus naïve population. This obstacle, in our point of view, is caused by the presence, in almost all subjects, of a cellular T and B cross-reactive memory produced during past exposures to the common cold coronaviruses. Due to this interference, it is difficult for a vaccination with the Spike protein alone, without adjuvants capable of prolonging the late phase of the generation of the immunological memory, to be able to determine the production of protective LLPCs. This would explain the possibility of previously and completely vaccinated subjects to become infected, already 4–6 months after the completion of the vaccination cycle.
“I Didn’t Come Here to Make Trouble”: Resistance Strategies Utilized by Transgender and Gender Diverse Youth in the Midwestern U.S.
Authors: Paceley Megan S. , Goffnett Jacob , Diaz April L. , Kattari Shanna K. , Navarro Jennifer , Greenwood Emera
Published: December 2021

Research on transgender and gender diverse (TGD) youth demonstrates the negative outcomes associated with trauma and oppression based on gender identity and expression. Related research illustrates how TGD youth are resilient in the face of oppression through individual (e.g., navigating difficult relationships, seeking mental health support) and community (e.g., access to community resources) factors. However, this research is limited by an understanding of resilience as overcoming challenges rather than exploring the possibly unique ways that TGD youth resist oppression as a form of resilience. This qualitative study utilized in-depth interviews with 19 TGD youth living in two Midwestern states, a region of the U.S. characterized by high levels of hostility and victimization toward TGD young people. Thematic analyses revealed the ways in which TGD youth engage in resistance strategies in the face of oppression. At an intrapersonal level, strategies included resisting oppressive narratives, affirming one’s own gender, maintaining authenticity, and finding hope. At an interpersonal level, strategies were standing up for self and others, educating others, and avoiding hostility. Finally, at a community-level, TGD youth were engaging in activism and organizing and enhancing visibility and representation. Findings are discussed and implications are identified.
USO POPULAR E COMPROVAÇÃO CIENTÍFICA DA PLANTA SIPARUNA GUIA-NENSIS EM DIFERENTES REGIÕES DO PAÍS
Authors: De Oliveira Anny Caroline Oliveira
Published: December 2021

A Siparuna guianensis é uma planta conhecida popularmente como negramina. Ela compõe a flora das angiospermas, é encontrada no cerrado brasileiro e é usada em diferentes regiões do mundo, principalmente em tribos indígenas. Na medicina popular, as suas folhas são utilizadas como antiflamatório e estimulante para o tratamento da herpes, dor de cabeça, reumatismo, artrite e malária, além de serem usadas para a decoração. O consumo do seu fruto in natura é eficaz para dores abdominais e indigestão. Ademais, é importante ressaltar que o óleo dessa planta é um excelente inseticida. Nesse sentido, o objetivo desse trabalho é realizar uma pesquisa bibliográfica, dando ênfase no uso popular e comprovação científica da Siparuna guianensis.
RELAÇÃO ENTRE ÍNDICE DE DESENVOLVIMENTO HUMANO E NÚMERO DE CASOS DE COVID-19 EM CIDADES DO TOCANTINS
Authors: Panontin Juliane Farinelli , Ferreira Neto Domingos Marques , Morbeck Natália Belo Moreira , Welter Áurea
Published: December 2021

No final do ano de 2019, aproximadamente em dezembro, aparece uma nova enfermidade do trato respiratório bastante propagativa na China, nomeada de COVID-19, a qual se alastrou ligeiramente por diversos países fazendo com que a Organização Mundial da Saúde (OMS) decretasse estado de pandemia. Cidades que apresentam uma maior vulnerabilidade podem apresentar uma disseminação maior da COVID-19. O presente estudo teve como objetivo relacionar o IDH com o número de casos de COVID-19 em cidades tocantinenses. Para tanto, foi realizado um estudo descritivo retrospectivo, exploratório, no qual foram analisados 20 municípios do estado do Tocantins, selecionando os 10 municípios com maior IDH e os 10 municípios com menor IDH, de acordo com censo de 2010. Os dados coletados foram tabulados no software Excel e foi realizada análise de correlação no R 4.1.1. Foi usado a correlação de Spearman no programa R version 4.1.1 onde o valor obtido de ρ(rho) foi analisado. A partir dos resultados obtidos, observa-se que o IDH da cidade tem relação com o índice de casos por 1.000 habitantes, quando for levado em consideração o número de incidência, pois os seis primeiros municípios com maior taxa de incidência pela COVID-19 têm um IDH alto, ou seja, quando feito a correlação dos dados levando em consideração o número de incidência de casos em todas as cidades relacionado ao IDH, verificou-se que cidades com maior população apresentaram uma proliferação maior da COVID-19. Com o levantamento realizado, verificou-se que no Tocantins, a disseminação da COVID-19 em relação ao IDH, foi bem maior em cidades IDH alto devido, possivelmente à maior movimentação de pessoas.
The Network Effect of Arts Incubators
Authors: Renard Stan , Zanella Gianluca
Published: December 2021

Although there has been a proliferation of metrics to evaluate arts incubators, the academic field is still developing. Different models and methods of education are applied to the complex phenomena of arts incubators; therefore, it is crucial to measure the effectiveness of education programs from many different perspectives. Our aim is to propose a metric that can estimate the effect of each incubator activity based on the geospatial distribution of its participants. This GIS-based metric will provide a descriptive measure for the quantity and density of the geographical communities affected by the incubator’s activity as well as a socio-economic and demographic benchmarks. Our study investigates 14 US-based arts incubators that offer entrepreneurial training to their associated 1,087 incubatees. The goal of this study is to provide a metric that can assist arts incubators, program directors, arts administrators, and university programs assess program growth as well as funding and marketing efforts.
Book Review: Can Music Make You Sick? Measuring the Price of Musical Ambition by Sally Anne Gross & George Musgrave
Authors: Kuuskoski Jonathan
Published: December 2021

Book Review of Can Music Make You Sick? Measuring the Price of Musical Ambition by Sally Anne Gross & George Musgrave (University of Westminster Press, 2020)
Editors Introduction
Authors: Vakharia Neville , Bonin-Rodriguez Paul
Published: December 2021

Editors' Introduction to Issue 10.2
Migracije u naravi i poslanju Crkve. Temeljni stavovi i posebni teološki izazovi
Authors: Punda Edvard , Rapić Darko
Published: December 2021

Jedan od velikih fenomena današnjeg svijeta, a time i jedan od velikih izazova koji se stavlja pred Crkvu jesu migracije. U ovome se članku pokušava teološki promišljati o tom fenomenu, o značenju koje on ima za Crkvu, te o posebnosti izazova koji migracije stavljaju pred teologiju. Najprije se pokazuje kako je Crkva ozbiljno pristupala tom fenomenu tijekom čitave svoje povijesti. Međutim, nemoguće je obuhvatiti raspon djelovanja Crkve na tom području. Jednako je i kada se želi prikazati sve intervencije učiteljstva i teološke perspektive pristupa migracijama. Stoga ovdje ukratko predstavljamo najvažnije dokumente crkvenog učiteljstva, te istaknuto mjesto koje migracije imaju u pontifikatu pape Franje. Potom se, u drugome dijelu, pokušava pokazati kako je fenomen migracija u samoj naravi Crkve, koja je putujuća i misionarska. Te su dvije dimenzije, iako različite, neodvojive. Crkva nije samo usmjerena prema migrantima nego je ona trajno migrirajuća ukoliko je uvijek na putu prema svome konačnom dovršetku u nebeskoj slavi. Ona je također migrirajuća ukoliko je poslanje Kristovih učenika ići svim narodima, ali i ukoliko vjera Kristovih učenika podrazumijeva trajni nutarnji izlazak. U trećem se dijelu pokušava dati vlastito shvaćanje posebnosti teološkog promišljanja o migracijama, koje se opisuje kroz dvije perspektive, dogmatsku i evangelizacijsku. Na kraju, u zaključku, sažima se važnost migracija za vjeru i Crkvu, te se pokazuje kakvu teologiju zahtijeva fenomen migracija.
Kult svetog Nikole – mijene kroz
povijest i uloga u izgradnji suvremenog identiteta Dubrovnika
Authors: B. Lupis Vinicije , Hazdovac Bajić Nikolina
Published: December 2021

Dubrovnik je važan kulturni i vjerski topos na nacionalnom ozemlju, grad na svojevrsnom raskršću uljudbenih sustava, koji je, uz vjerski i državni kult sv. Vlaha, prepoznat i kao najjužniji grad s urbanim svjetovnim kultom viteza Orlanda. Ovim gradskim vjerskim i svjetovnim kultovima u Domovinskom se ratu pridružio i treći – kult sv. Nikole. Na dan sv. Nikole 6. siječnja 1991. godine zbio se najteži napad srpsko-crnogorskih agresora na grad, pa je stoga taj dan proglašen i Danom branitelja Dubrovnika. Vjerski kult sv. Nikole od 1991. godine dobiva tako posve novu dimenziju i priključuje se drugim urbanim simbolima Grada. Sv. Nikola postaje u suvremenoj memoriji Grada kult sveca zaštitnika branitelja Domovinskog rata. Ovdje se radi o posve jedinstvenom fenomenu u razvoju kulta sv. Nikole u svjetskim razmjerima, koji postaje antiratni svetac i svetac obranitelj. Cilj je ovoga rada, na interdisciplinaran način, kombinirajući povijesnu i sociološku perspektivu, steći prvi znanstveni uvid u međusobni odnos koncepata religijskog simbola, identiteta i zajednice na primjeru razvoja, promjene i značenja kulta sv. Nikole u Dubrovniku kroz povijesni kontinuitet do suvremenih zbivanja.
Penerapan Association Rule Menggunakan Algoritma Apriori Pada Poliklinik Penyakit Dalam (Studi Kasus: Rumah Sakit Umum Daerah Bintan)
Authors: Nola Ritha  , Suswaini Eka , Pebriadi Wisnu
Published: December 2021

Rekam Medis merupakan berkas yang berisi tentang identitas pasien, pemeriksaan, pengobatan, tindakan serta pelayanan yang diberikan kepada pasien. Data rekam medis seiring waktu akan terakumulasi setiap hari seiring dengan aktivitas di rumah sakit. Selama ini data rekam medis yang tersedia di Rumah Sakit Umum Daerah Bintan hanya menampilkan informasi berupa data statistik maupun grafik. Sedangkan, pola dan kecenderungan penyakit yang diderita oleh pasien masih belum di gali untuk dijadikan acuan untuk penyuluhan ke masyarakat maupun sebagai pencegahan penyakit, terutama data rekam medis yang berasal dari Poliklinik Penyakit Dalam. Poliklinik Penyakit Dalam merupakan salah satu Poliklinik yang banyak melayani pasien di Rumah Sakit Umum Daerah Bintan, sehingga data rekam medis yang berasal dari Poliklinik Penyakit Dalam belum bisa digali secara maksimal. Pada penelitian ini penulis melakukan penerapan Algoritma Apriori dalam menentukan aturan asosiasi berdasarkan jenis kelamin, umur, kelurahan, dan kode ICD10. Dengan menggunakan data sebanyak 1668 dan menggunakan minimal support sebesar 6% dan minimal confidence sebesar 50%, kemudian didapatkan hasil aturan asosiasi sebanyak 22 aturan. Aturan asosiasi yang dihasilkan pada penelitian ini dapat digunakan oleh pihak rumah sakit maupun pihak dinas kesehatan untuk melakukan sosialisasi dan penyuluhan kesehatan kepada masyarakat.
Направления реализации стратегии национальной безопасности стран Балтийского региона
Authors: Bolshakov Sergey
Published: December 2021

The article analyzes the strategy and principles of building the national security strat-egy of the Russian Federation, considers the priorities of ensuring national security. Security doc-trines are aimed at security in the military, political, and informational environment. The article highlights the priority tasks in the field of national defense of the Russian Federation. The review analyzes the integrated security strategies of the countries of the Baltic region – Estonia, Lithuania, Latvia; analyzes the effectiveness of the doctrine of “total defense” of Estonia, the procedure and forms of its implementation. It is stated that the Baltic countries are considering various options to improve security, the concept of “total defense”, is based on the protection of the position of neu-trality, the defense policy of the countries is based on cooperation with large European and regional countries (Finland, Sweden, Poland). The article states that the military security of countries is associated with the need to deepen cooperation with NATO. The doctrine of territorial defense of Estonia, Latvia, Lithuania, directions of defense policy and territorial security is analyzed.
piel y la cicatriz colonial. El desgarramiento y la escisión en dos artistas feministas palestina e israelí:
Authors: Bidaseca Karina
Published: December 2021

El artículo aborda los devenires palestinos a través de las prácticas artísticas feministas sensibles al concepto que creé, el del desgarramiento de la “cicatriz colonial” en los territorios palestinos ocupados. A partir de la obra de dos artistas de un lado y otro del muro: la obra de la artista palestina en la diáspora Emily Jacir, quien con su técnica de pantallas divididas e imágenes dobles nos permite inferir la escisión de esa herida colonial aún latente. La obra de la artista israelí Sigalit Landau cuya obra Hula Barbed (2000) es metáfora visceral del desgarramiento de su piel por el roce del alambre de púas, una metáfora de esa cicatriz en estos tiempos de crímenes de lesa humanidad, colonialismo y apartheidización de Palestina (Bidaseca, 2018). Ya no la piel como umbral de la racialización compulsiva sino la carne, ya no sólo la herida abierta sino es preciso tocar esas zonas sensibles de nuestra cicatriz colonial.
Design of edges in contour and half moons from edaphoclimatic parameters, for the endorrheic basin of lagunas de tajzara - ramsar site 1030
Authors: Schmidt-Gomez Armando , Olivares-Ramírez Juan Manuel , Ferriol-Sánchez Fermín , Marroquín-De Jesús Ángel
Published: December 2021

The collection of water is proposed from the design of contour borders and half moons, green infrastructure measures, to reduce surface runoff and increase the availability of water for vegetation. The contour and crescent ridges have land ridges with a trapezoidal section, which follow the contour lines, to compartmentalize the slope into smaller hydrological units, the ends of which are located on contour lines. With the data of maximum rainfall every 24 hours and parameters of Gumbel's Law modified, the equations of maximum daily rainfall height (hdT), rainfall height for a duration ´´t´´ (htT), and the Intensity Duration Frequency curve (ItT), for a duration of t <2h. Then considering the values of basic infiltration, vegetation cover, soil type and hydrological condition, the curve numbers were determined for different soil moisture conditions, later the separation length (L) between the Half Moons, and the borders was calculated. in contour, which were designed by means of 10 configurations between diameter and height, for the two infrastructures, being in Copacabana Valle, the greatest separation distance.
Ergonomic culture level in managers and supervisors in manufacturing centers
Authors: López-Acosta Mauricio , Chacara-Montes Allán , Velarde-Cantú José Manuel , Ramírez-Cárdenas Ernesto
Published: December 2021

The purpose of the following project is to measure the level of ergonomic culture of a manufacturing company that is dedicated to the development of cables, fiber optics, cabling systems and related services for the automotive sector and cable systems; To carry out this study, the ergonomic culture questionnaire in work centers (CCE-T) was used as a tool and it was applied to a sample of 26 people between supervisors and managers. This questionnaire made it possible to measure the level of development of ergonomic culture in work centers from the perspective of supervisors and senior management (managers) and to know their perception of the development and application of ergonomics in their company. Therefore,
Using Learning Theories to Develop a Veterinary Student Preparedness Toolkit for Workplace Clinical Training
Authors: Routh Jenny , Paramasivam Sharmini , Cockcroft Peter , Nadarajah Vishna Devi , Jeevaratnam Kamalan
Published: December 2021

Learning theories are logically related statements designed to explain what should or could be aspired to in establishing ideal learning conditions. Multiple theories can inform our understanding of a single concept, in this case: veterinary workplace clinical training (WCT), which occurs just prior to students’ graduation as competent veterinary surgeons. The competency movement has strongly influenced reforms in veterinary education and is considered important. In reflection of this, the term “preparedness” is operationalised here as a measure of the likelihood that the veterinary student is going to be a competent learner and participant during WCT. Preparedness itself is therefore important because it directly impacts performance. Workplace clinical training is explored through the lenses of cognitivist, social constructivist and socio-culturalist learning theories and used to inform student preparedness characteristics in terms of their behaviours, personal attributes, knowledge and skills, and awarenesses to optimise learning and participation.
HAK ATAS TANAH SEBAGAI SARANA DALAM PENANAMAN MODAL
Authors: Ramadhan Adrian Wahyu , Putri Gelza Sectine , Putri Dianita Hani
Published: December 2021

kemudahan pelayanan hak atas tanah yang diberikan oleh Pemerintah kepada penanam modal berdasarkan Undang – Undang Penanaman Modal dan Undang – Undang Pokok Agraria. Metode penelitian yang digunakan penulis adalah penelitian normatif, serta dilakukan pendekatan undang – undang dan juga secara konseptual. Pentingnya suatu pemahaman tentang konsep kemudahan pelayanan terkait hak atas tanah yang diberikan bagi penanam modal, khususnya mengenai Hak Guna Usaha, Hak Guna Bangunan dan juga Hak Pakai, karena tidak semua orang tahu dan konsep tersebut sangat luas jangkauannya yang tersebar dalam berbagai macam undang – undang. Kemudian pemahaman mengenai pentingnya suatu insentif yang harus diberikan pemerintah dalam penerapan kemudahan pelayanan dimana hal tersebut sangat dibutuhkan dalam kegiatan investasi. Pemerintah perlu membuat suatu aturan secara eksplisit terkait fasilitas dan juga jaminan kegiatan investasi yang belum diatur dalam peraturan – peraturan yang telah ada.
MUTUAL LEGAL ASSISTANT DALAM PENYIDIKAN TINDAK PIDANA PERDAGANGAN MANUSIA MELALUI MEDIA SOSIAL SEBAGAI KEJAHATAN TERORGANISASI TRANSNASIONAL
Authors: Salsa Shidqi Noer
Published: December 2021

AbstrakPerdagangan manusia merupakan kejahatan yang tidak hanya terjadi di Indonesia namun juga di pelbagai negara yang saat ini dilakukan dengan pemanfaatan sosial media. Permasalahan yang timbul dalam hal ini adalah sejauhmana penerapan Mutual Legal Assistant (MLA) yang dilakukan oleh penegak hukum dalam penyidikan tindak pidana perdagagang manusia yang merupakan kejahatan terorganisasi transnasional. Tujuan penelitian ini untuk mengetahui sejauhmana penerapan MLA dalam upaya penyidikan untuk melengkapi barang bukti dan alat bukti untuk menjerat pelaku tindak pidana perdagangan orang yang dilakukan dengan cara yang semakin cangih, yaitu dengan pemanfaatan aplikasi digital sosial media. serta tidak hanya melibatkan warga Negara Indonesia, namun juga dilakukan oleh warga Negara asing dan dilakukan di beberapa Negara. Metode dalam penelitian ini menggunakan pendekatan yuridis normatif, yaitu permasalahan yang muncul dilapangan dikaji dari bahan-bahan hukum seperti buku atau artikel yang membahas tentang perdagangan orang sebagai referensi bahan pokok dan bahan hukum sekunder. Hasil penelitian menunjukan masih ditemukan kendala penerapan MLA terhadap penyidikan perdagangan manusia yang diakibatkan oleh masalah prosedural akibat dari belum semua Negara mengatur kerjasama MLA, selain itu biaya tinggi, dan hubungan Negara peminta terhadap Negara yang diminta tidak harmonis juga menjadi penyebab tidak maksimalnya penerapan MLA.
EFEKTIVITAS HUKUM PEMBATASAN JAM MALAM DALAM RANGKA PENCEGAHAN DAN MEMUTUS MATA RANTAI PENYEBARAN COVID-19 DI KOTA SURABAYA
Authors: Syafaadin Mohammad Ricky , Wahyudi Eko
Published: December 2021

Hadirnya aturan pembatasan jam malam di Kota Surabaya sendiri berbuntut dari Pandemi Covid-19 yang masih belum terkendali, aturan ini dijalankan dengan membatasi kegiatan masyarakat/tmpat usaha yang tidak berkepentingan di malam hari pukul 22.00-04.00 WIB, pada penelitian ini berfokus guna mengetahui efektivitas hukum dari jalannya pembatasan jam malam yang sedang berlaku di surabaya, karena memang berdasarkan temuan awal penulis di lapangan masih banyak pelanggaran, aturan tersebut termuat di dalam Peraturan Walikota Surabaya Nomor 67 Tahun 2020 dalam penelitian ini bahasannya berfokus pada analisis pelaksanaan pembatasan jam malam dengan didukung data dari instansi terkait, serta wawancara dengan beberapa masyarakat terkait adanya aturan ini, serta kendala penegakan hukum pembatasan jam malam dan upaya mengatasi kendala tersebut. Penelitian ini menggunakan metode penelitian yuridis empiris yang merupakan penelitian terhadap efektivitas hukum pada hukum yang berlaku di masyarakat. Hasil penelitian ini dapat disimpulkan bahwa pembatasan jam malam ini telah dijalankan dengan efektif oleh instansi terkait dengan sanksi administrasinya namun dari memang dari sisi kepatuhan masyarakat pada aturan ini masih kurag efektif karena pelanggarannya masih cukup banyak, selain itu juga memang dalam penegakan hukumnya masih terdapat kendala dan diperlukan upaya mengatasi agar pelaksanaanya lebih baik lagi.Kata Kunci: Pembatasan Jam Malam, Efektivitas, COVID-19
TANGGUNG JAWAB NOTARIS YANG MEMBATALKAN AKTA ATAS PERMINTAAN PENJUAL SECARA SEPIHAK DALAM PERSPEKTIF UNDANG-UNDANG JABATAN NOTARIS
Authors: Amalia Rizki , Arifin Muhammad , Mansar Adi
Published: December 2021

Notaris sebagai salah satu profesi hukum yang sebagian wewenangnya adalah menerbitkan suatu dokumen berupa akta dengan kekuatan sebagai akta otentik.Kesalahandan kelalaian Notaris menyebabkan pembatalan akta Notaris disebabkan oleh kesalahandan kelalaian penghadap yang mengikatkan diri dalam akta Notaris itu, kesalahan dankelalaian kedua belah pihak maupun salah satu pihak mengakibatkan adanya atautimbulnya gugatan atau tuntutan dari salah satu penghadap terhadap akta. Hal inidapat dicermati dalam Putusan Pengadilan Negeri Kisaran Nomor657/Pid.B/2015/PN Kis. Permasalahan yang diangkat dalam tesis ini adalah bagaimana prosedur Notaris dalam mengeluarkan pembatalan akta secara sepihak, bagaimana akibat hukum terhadap Notaris dalam mengeluarkan pembatalan akta secara sepihak, bagaimana bentuk penyelesaian tanggungjawab hukum terhadap Notaris yang mengeluarkan pembatalan akta secara sepihak. Tujuan dari penelitian ini adalahuntukmengetahui dan menganalisis prosedur Notaris dalam mengeluarkan pembatalan akta secara sepihak, untuk mengetahui dan menganalisis akibat hukum terhadap Notaris dalam mengeluarkan pembatalan akta secara sepihak, untuk mengetahui dan menganalisis bentuk penyelesaian tanggungjawab hukum terhadap Notaris yang mengeluarkan pembatalan akta secara sepihak.Penelitian ini bersifat deskriptif analisis, jenis penelitian yang digunakan adalah penelitian hukum normatif (yuridis normatif). Teknik penumpulan data diperoleh dengan cara penelitian kepustakaan (library research) berupa studi dokumen. Analisis data menggunakan analisis kualitatif, selanjutnya ditarik kesimpulan dengan menggunakan metode berpikir deduktif. Alasan yuridisuntuk menyatakan batal demi hukum suatu akta Notaris adalah jikaakta Notaris tidak memenuhi persyaratan objektif dan subjektif dalam suatu perjanjian. Akibat hukum pembatalan akta Notaris yaitu berubahnya status dan kekuatan pembuktian suatu akta Notaris sebagai akta otentik menjadi akta di bawah tangan. Pertanggungjawaban Notaris terhadap akta yang dinyatakan batal demi hukum oleh pengadilan meliputi pertanggungjawaban perdata, pidana dan administrasi.Penelitian ini menyarankan agar Hakim harus membuat keputusan yang bijaksana dan seadil-adilnya dalam menangani setiap perkara, terutama yang berkaitan dengan akta Notaris. Setiap akta yang dibuat Notaris harus memenuhi persyaratan materil dan formil. Notaris harus siap dan bertanggungjawab terhadapsetiap produk akta yang dibuatnya, baik secara perdata, pidana dan administrasi
Hygienic Characteristics of the Digital Information and Educational
Environment and the Risk of Its Mental Health Impacts in Students with Different Degrees of Myopia
Authors: Setko NP , Korshunova RV , Bulycheva EV
Published: December 2021

Introduction: Today, educational conditions and the lifestyle of students of medical universities, coupled with active introduction of electronic educational resources, information and communication technologies and development of a digital
environment, pose a challenge of maintaining psycho-emotional wellbeing of students. This problem is especially relevant among students with myopia since, inter alia, the increasing visual load has a potential adverse effect on their mental and emotional health.
Objective: to give a hygienic characteristic of electronic information and educational environment and to assess its risk on students’ mental health with myopia of varying degrees.
Materials and methods: We assessed intensity of the educational process of 1,100 first to third-year students (aged 17 to 25 years) of the Orenburg State Medical University and analyzed data on the type, frequency and purpose of their using information and communication tools for study and leisure. We also conducted a questionnaire-based survey of 168 healthy students and 138 students with myopia to assess their mental health and determine the type of character accentuation, the anxiety level, and negative emotional experiences in educational and everyday life.
Results: We observed very intensive educational activities of the medical students against the background of the use of electronic gadgets by every second student for educational purposes lasting up to 4.8 hours a day and additional visual load
due to the use of a mobile phone by 93.6 % of students to visit social network sites more than five times a day with the total duration for every third person ranging from 25 to 50 minutes a day. We established that the presence and degree of myopia determined the anxious-pedantic type of character accentuation and a 1.3-fold increase in the anxiety level in everyday activities. In educational activities, it resulted in a 1.7-fold decrease in the level of anxiety and a 1.3-fold increase in the level of negative emotional experiences.
Conclusion: We established mental health risk factors of intense educational activities and an extensive use of information and communication tools by the students, including those with myopia, for study and leisure. Our findings prove the necessity of a differentiated approach to hygienic examination and regulation of various types of activities of the educational process in order to prevent the development and progression of myopia in medical university students.
Assessment of Health Risks Posed by Water Quality in the Centralized Supply Network of Private Sector Housing in Ufa
Authors: Rakhmatullina LR , Suleimanov RA , Valeev TK , Rakhmatullin NR , Rafikov SSh , Baktybaeva ZB
Published: December 2021

Background: At present, high-quality drinking water supply is challenging due to natural and anthropogenic pollution of the environment and remains a priority. The Federal Clean Water Project is aimed at improving the communal infrastructure in order to ensure chemical and microbiological safety of supplied water and to inform the public.
Objective: To assess priority health risk factors for the population of Ufa associated with tap water quality within the implementation of the Federal Clean Water Project in the Republic of Bashkortostan.
Materials and methods: We used data of the regional information fund of public health monitoring on eight street water pumps located in six administrative districts of the city for 2016–2018. The organoleptic risk associated with drinking water quality was assessed according to Method Recommendations MR 2.1.4.0032–11. Population health risk assessment was carried out in compliance with conditions and requirements of Guidelines R 2.1.10.1920–04.
Results: We established that chemical and microbiological quality indices of drinking water in street water pumps in 2016–2018 were below the permissible limits for all samples. Both organoleptic and non-carcinogenic risk estimates were within the
acceptable range. The carcinogenic risk for the population was less than a case. Yet, the presence of trihalomethanes and herbicides in tap water sampled in Olimpiyskaya Street posed unacceptable total carcinogenic health risk.
Conclusion: The study results were used to develop recommendations for appropriate preventive measures aimed to reduce chemical exposure of the population of Ufa through drinking water.
Criminalistics and criminal politics
Authors: Sotnikov Konstantin , Romanova Oksana
Published: December 2021

The article considers the question of the place and role of criminalistics in the implementation of the criminal policy of the state, examines the systemic relationship of criminalistics and criminal policy and the statements of individual criminologists about the need to form a forensic policy as an integral part of criminal policy are analyzed. The definition of the term «forensic policy» is formulated. The author regards the term as a strategic direction ensuring the implementation of criminal policy by the introduction in practice the most effective, accessible and economical forensic tools and methods to solve and investigate crimes. It is emphasized that at the present stage of development of society, in the conditions of globalization of the economy, challenges in the field of information technologies, environmental problems, interstate relations, the tasks of protecting fundamentally new relations and interests are being actualized. Legislators formulate new elements of crimes against property, in the field of economics, violations of tax legislation, protection of the financial and banking system, information technologies, as well as crimes related to systemic corruption. In this regard, criminology faces the task of timeliness and adequacy of scientific developments of the crime mode, qualitative changes in legislation and forecasting the needs of practice in combating crime. The digitalization of the preliminary investigation should become the most important direction of the implementation of the forensic policy. The author raises the question of the development of a forensic strategy and the formulation of a forensic policy. It is proposed to develop a strategy (concept, program) for the development of criminalistics as an applied science for 5-10 years with the participation of the leading criminalistics departments of the universities of the country. This document will be discussed and adopted at the All-Russian Congress of Criminologists.
Graffiti as an example of a new kind of objects for handwritten expertise. Styles and variants
Authors: Yaskina Valentina
Published: December 2021

In this article one can find examples of the analytical work based on a current terminology of a word “graffiti”, that can be found in scientific research works on this phenomenon in the fields of sociology, psychology, art and law. Current classifications of this notion are analyzed taking into account the content of these objects, their attitude to a graffiti community and a certain author, motivation and outward. Analysis considers materials and tools used for a certain object implementation. These writing tools in some cases determine the type of graffiti.

The main objective of this analysis was the need to identify certain classified objects the ones that might be necessary for a handwriting expertise and to determine of the relations between the notions of “graffiti” and “handwritten objects made with the use of unconventional writing materials”.

During the analysis, a number of characteristics that can be used as a support for conducting handwritten expertise of considered object were defined and conclusions for those graffiti objects that meet these criteria were drawn.
Social perceptions of convicts about the attitude of society towards ever imprisoned persons
Authors: Suchkova Elizaveta
Published: December 2021

The article analyzes the content of the social perception of convicts about the attitude of society towards ever imprisoned persons. It is noted that the very fact of a conviction often causes a wary attitude of people towards former convicts, which significantly complicates the process of their adaptation to life in freedom. The negative assessment of the personality and behavior of criminals which still persists in public opinion even after they have served their sentence and this contributes to the fact that convicts feel themselves as a group being subjected to stigmatization. An empirical study tested the hypothesis that in convicted persons’ view, who have served their sentences in places of deprivation of liberty, are still criminals in public opinion who constitute a menace even after their release. The assessment of society position about people with conviction by convicts is associated with the experience of those who were in places of liberty deprivation. Repeatedly convicted persons as compared with those who were convicted for the first time are surer in negative and biased treatment of former prisoners.

To study the content of social perceptions a mixed research strategy was used. It consists in integrating of methods for collecting and analyzing data of qualitative and quantitative strategies. The study used specially designed interview plan and rating scale constructed on the basis of the data obtained with its help. The research sample includes groups of convicts formed depending on the number of sentences served. The results of the research allow us to conclude that in convicts’ perception there is a negative society attitude towards former prisoners which manifests itself in social distance from them in various spheres of social interaction. Persons who have previously served their sentences in places of deprivation of liberty, unlike those convicted for the first time, demonstrate greater confidence in the discriminatory nature of society’s attitude towards their group.
MENINJAU ORGANIZATIONAL CITIZENSHIP BEHAVIOR PADA KARYAWAN MELALUI IKLIM ORGANISASI DAN KEPUASAN KERJA
Authors: Aswitama Fathimah Khansha , Qomariyah Nurul
Published: December 2021

Organizational citizenship behavior (OCB) saat ini menjadi perhatian penting dalam sebuah organisasi karena mampu meningkatkan kemampuan karyawan untuk memperbaiki efisiensi, efektivitas, dan kreatifitas organisasi melalui kontribusinya dalam transformasi sumber daya, inovasi, dan kemampuan beradaptasinya. Penelitian ini bertujuan untuk meninjau organizational citizenship behavior (OCB) pada Karyawan Melalui iklim organisasi dan kepuasan kerja. Penelitian ini menggunakan pendekatan kuantitatif dengan partisipan penelitian berjumlah 185 karyawan yang diperoleh melalui teknik purposive sampling. Metode analisis data yang digunakan adalah regresi sederhana dan berganda. Berdasarkan hasil analisis data dengan menggunakan regresi berganda, diketahui bahwa semua hipotesis diterima. iklim organisasi dan kepuasan kerja secara bersama-sama terhadap OCB sebesar 28.2%, dimana iklim organisasi berkontribusi yang lebih besar terbentuknya OCB sebesar 27.1% dan kepuasan kerja berkontribusi terbentuknya OCB sebesar 15,3%.
HUBUNGAN QUARTER-LIFE CRISIS DAN SUBJECTIVE WELL-BEING PADA INDIVIDU DEWASA MUDA
Authors: Suyono Tsana Afrani , Kumalasari Asteria Devy , Fitriana Efi
Published: December 2021

Masa dewasa muda ditandai dengan adanya tugas perkembangan untuk mulai mengambil peran dan tanggung jawab sebagai individu yang produktif dalam bidang pekerjaan dan karir, relasi, dan finansial. Pada masa ini, individu dewasa muda mengalami berbagai tantangan dan kesulitan yang dapat memunculkan emosi negatif yang nyata dan sering disebut sebagai quarter-life crisis. Di sisi lain, produktivitas individu juga dipengaruhi oleh tingkat well-being individu. Penelitian ini bertujuan untuk mengetahui hubungan antara quarter-life crisis dan subjective well-being pada individu dewasa muda. Penelitian ini merupakan penelitian kuantitatif dengan metode korelasi yang melibatkan 126 responden mahasiswa dalam rentang usia 20-23 tahun yang terpilih menggunakan teknik sampel acak klaster. Pengambilan data dilakukan secara daring menggunakan Google form. Alat ukur yang digunakan dalam penelitian ini adalah alat ukur Quarter-Life Crisis, Satisfaction with Life Scale (SWLS), dan Scale of Positive and Negative Experience (SPANE). Analisis statistik yang digunakan adalah uji korelasi Pearson. Hasil analisa data menunjukkan bahwa quarter-life crisis berkorelasi negatif dengan kepuasan hidup dan afek positif, namun berkorelasi positif terhadap afek negatif. Dapat disimpulkan terdapat hubungan yang signifikan antara quarter-life crisis dan subjective well-being.
CARA MENGATASI INFERIORITAS PADA ATLIT BERPRESTASI PEREMPUAN PENDERITA SKELIOSIS
Authors: Prabowo Hendro , Fauziah Alia Rizki , Mahendra Nabiel Y.
Published: December 2021

Skoliosis menurut National Institute of Arthitis and Musculoskeletal and Skin Disease (NIAMS) USA merupakan kelainan muskuloskeletal yang digambarkan dengan bengkoknya tulang belakang ke arah samping. Penelitian ini bertujuan untuk mengetahui (1) Bagaimana gambaran mengenai inferioritas pada perempuan penderita skoliosis, (2) faktor-faktor apa saja yang menjadi penyebab inferioritas pada perempuan penderita skoliosis, serta (3) bagaimana gambaran striving for superiority pada perempuan penderita skoliosis. Penelitian ini menggunakan metode kualitatif berbentuk studi kasus pada seorang atlit berprestasi perempuan penderita skoliosis dengan jenis “S” dengan derajat kemiringan 19 derajat. Hasil dalam penelitian ini pada gambaran inferioritas meliputi (1) penyakit masa kecil, (2) merasa dibedakan dan kesal, (3) ketakutan terhadap ayahnya, (4) suka menyendiri, (5) merasa psikologisnya tidak sehat dan didiagnosis PTSD, (6) menyerah akan kondisi keluarga, (7) skoliosis, (8) merasa sedih, serta (9) khawatir dengan postur tubuh dan ragu akan kondisinya. Kemudian pada faktor penyebab inferioritas meliputi (1) kekerasan dari ayah, (2) dihukum, dan (3) dibedakan. Selanjutnya, gambaran striving for superiority meliputi (1) les dan bimbel, (2) mengikuti lomba, (3) mendapatkan penghargaan, (4) beladiri, dan (5) termotivasi dari Usain Bolt.
FACTOR ANALYSIS METHOD APPLICATION FOR CONSTRUCTING OBJECTIVE FUNCTIONS OF OPTIMIZATION IN MULTIMODAL TRANSPORT PROBLEMS
Authors: Zabolotnii Serhii , Honcharov Artem , Mogilei Sergii
Published: December 2021

The paper regards a specific class of optimization criteria that possess features of probability. Therefore, constructing objective function of optimization problem, the importance is attached to probability indices that show the probability of some criterial event or events to occur. Factor analysis has been taken for the main method of constructing objective function. Algorithm for constructing objective function of optimization is done for criterion of minimization risk level in multimodal transportations that demanded demonstration data. The application of factor analysis in classical problem solution was shown to give the problem a more distinct analytical interpretation in solving it.
METHOD OF MEASUREMENT AND REDUCTION OF THE ELECTROMAGNETIC DISTURBANCES INDUCTED BY SWITCHING SURGES IN LV CIRCUITS
Authors: Wąsik Patryk
Published: December 2021

This paper presents a fast, reliable and portable method for measuring electromagnetic disturbances in LV circuits (overcurrent circuit breakers). The experiment was carried out under conditions reflecting the real measurement environment. The method was verified and confirmed by a series of measurements with passive components reducing the disturbance. The results of the measurements made it possible to obtain suitable EMI reduction solutions, which can be used to protect commutators or end consumers. The results obtained make it possible to apply the method to measurements of multichannel circuit breakers, in which measuring the turn-on time of individual channels is important for the correct operation of the devices.
APPLICATION OF THE THREAT INTELLIGENCE PLATFORM TO INCREASE THE SECURITY OF GOVERNMENT INFORMATION RESOURCES
Authors: Nikolaienko Bohdan , Vasylenko Serhii
Published: December 2021

With the development of information technology, the need to solve the problem of information security has increased, as it has become the most important strategic resource. At the same time, the vulnerability of the modern information society to unreliable information, untimely receipt of information, industrial espionage, computer crime, etc. is increasing. In this case, the speed of threat detection, in the context of obtaining systemic information about attackers and possible techniques and tools for cyberattacks in order to describe them and respond to them quickly is one of the urgent tasks. In particular, there is a challenge in the application of new systems for collecting information about cyberevents, responding to them, storing and exchanging this information, as well as on its basis methods and means of finding attackers using integrated systems or platforms. To solve this type of problem, the promising direction of Threat Intelligence as a new mechanism for acquiring knowledge about cyberattacks is studied. Threat Intelligence in cybersecurity tasks is defined. The analysis of cyberattack indicators and tools for obtaining them is carried out. The standards of description of compromise indicators and platforms of their processing are compared. The technique of Threat Intelligence in tasks of operative detection and blocking of cyberthreats to the state information resources is developed. This technique makes it possible to improve the productivity of cybersecurity analysts and increase the security of resources and information systems.
INCREASING THE COST-EFFECTIVENESS OF IN VITRO RESEARCH THROUGH THE USE OF TITANIUM IN THE DEVICE FOR MEASURING THE ELECTRICAL PARAMETERS OF CELLS
Authors: Zarzeczny Dawid
Published: December 2021

Currently, various methods are used to assess the biocompatibility of materials. After an in-depth and detailed review of the literature, the method used in the research was selected. As part of the experiments, a method based on the analysis of the values ​​of electrical parameters of cell cultures measured in the presence of electrodes was used. The electrode is a structure made of a thin layer of metallization. It measures the change in resistance, impedance and capacity of a mixture of cells and the substance in which they are grown. The plate containing the electrode assembly is called the measurement matrix. Currently, commercially used test matrices are made of gold or platinum. However, their high price means that large-scale research is significantly limited. In order to increase the access to the widespread use of this method, it was decided that it was necessary to use cheaper materials, reducing the necessary costs of conducting experiments. Considering this, an attempt was made to use a different conductive material to build matrices compatible with the ECIS® Z-Theta measurement system. Their use would enable in vitro research on living cells. In the presented work, titanium was used as a material that may turn out to be an alternative to the materials currently used. Its application to the production of matrices will allow to study the influence of this metal on the behavior of cells.
FIBRE OPTIC BRAGG STRUCTURES WITH MONOTONIC APODISATION CHARACTERISTICS
Authors: Klimek Jacek
Published: December 2021

The article discusses the principle of operation and the structure of chirped and uniform gratings. It presents the method of producing gratings with monotonic apodisation characteristics, and compares the spectral features of produced gratings with the those obtained by mathematical modelling.
STEROWANIE CZTEROPRZEWODOWYM TRÓJPOZIOMOWYM PRZEKSZTAŁTNIKIEM AC/DC Z NIEZALEŻNĄ KONTROLĄ MOCY W KAŻDEJ Z FAZ
Authors: Stefańczak Bartłomiej
Published: December 2021

W artykule przedstawiono projekt czteroprzewodowego trójpoziomowego przekształtnika AC/DC. Sterowanie przekształtnika zrealizowano z wykorzystaniem regulatorów proporcjonalno-rezonansowych opartych na sterowaniu zorientowanym napięciowo (VOC). Zaimplementowana topologia przekształtnika AC/DC pozwala na sterowanie każdą z faz z osobna. Przekłada się to możliwość niezależnej kontroli mocy czynnej i biernej w każdej z faz. Ponadto szyna DC przekształtnika AC/DC połączona jest równolegle z magazynem energii poprzez izolowaną przetwornicę DC/DC oraz odnawialne źródło energii. Badania przeprowadzono z wykorzystaniem zaprojektowanego przekształtnika, sterownika DSP oraz platformy Matlab/SIMULNIK, którą wykorzystano do automatycznej generacji kodu. Otrzymane wyniki wskazują, że sterowanie niezależne każdą z faz jest możliwe jednakże, praca z dużymi asymetriami mocy na każdej z faz prowadzi do dużej pulsacji prądu na szynie DC. Jest to zjawisko zagrażające poprawności działania magazynu energii. W skutek tego poziom asymetrii między fazami powinien być ograniczony do poziomu akceptowalnego przez magazyn energii.