bluuebunny/crossref_metadata_2025 huggingface dataset:
Towards Sustainable Forest Management: Assessing and Predicting Landuse/cover Change on Forest Landscape and Estimating its Impact on Forest Health in Southeast Georgia, USA
Authors: Batame Michael , Kanjin Kingsley
Published: September 2024

The conversion of LULC classes into other types is occurring at a faster rate globally including United States. Many studies have examined the drivers and causes of LULC changes, particularly, in northeast Georgia and Atlanta in the United States, while the case of southeast Georgia remains unstudied. Thus, this study filled the gap by quantifying and predicting the impact of LULC change on forestlands and how these LULC changes have affected forest health. The study used Landsat images, including 2005 and 2023 together with the random forest algorithm to perform LULC classification on the Google Earth Engine. Also, the study predicted how LULC will impact forest cover by 2050. The results revealed that forest hectares have generally changed approximately from 65% to 62% between 2005 and 2023, and this is projected to likely further decline to about 53% by 2050. This change in forest acreage has resulted decline in the health of the forest, that is the NDVI values changed from 0.992 to 0.866 between 2005 and 2023. The study concludes that the forest cover in southeast Georgia has changed to urban features over the years. Agriculture land is projected to gain most of the forest cover by 2050.
Petrographic and Geo-Mechanical Characteristics of Inzari Formation of Nizampur Basin, Nowshera District, Khyber Pakhtunkhwa, Pakistan
Authors: Ayaz Hassan , Xu Jaincong , Aslam Muhammad Usama , Ahmad Sohail , Ali Junaid
Published: September 2024

This study is focus on the petrographic properties and geo-mechanical properties of the Inzari formation rocks at Tar Khel Village, District Swabi, Khyber Pakhtunkhwa, and whether they are suitable for use as building materials for structures like bridges, buildings, and roads. Five fresh and large samples have been taken from various areas of this formation. These rock samples were identified as siliciclastic mudstone through a careful petrographic analysis. The test result of physical properties (water absorption, specific gravity, and porosity) and mechanical properties (unconfined compression strength, unconfined tensile strength, Schmidt hammer test, and shear strength) of these rock samples shows as follows: their unconfined compressive strength with between 23 to 94 MPa, their specific gravity values being very high (≥2.78), and their porosity and water absorption values being very low (<1%), imply that the Inzari formation rock can be used as an excellent building material. The rock sample strength variations may be mainly caused by the presence and abundance of stylolite and fractures. Furthermore, the petrographic property analysis of these rock samples indicates that they have the significant amount of micrite and calcite, which are suitable to be use as both asphalt and concrete aggregate. According to this study, the Inzari formation rock is appropriate for use as fine aggregate in concrete, asphalt, and other building materials.
Translation, Cultural Adaptation of the Portuguese Provider Attitudes toward Cardiac Rehabilitation and Referral (PACRR-P) Scale and Assessment of its’ Measurement Properties
Authors: Cruz Mayara Moura Alves da , Vanderlei Luiz Carlos Marques , Takarashi Carolina , Laurino Maria Julia Lopez , Cruz Murilo Reis Alves da , Grace Sherry L , Ghisi Gabriela L M
Published: September 2024

The access to cardiac rehabilitation (CR) is contingent upon physician referrals, yet these are often inadequate, particularly in low-resource settings. This multi-method study aimed to translate, culturally adapt, and validate the Portuguese version of the Provider Attitudes toward CR and Referral (PACRR-P) scale, as well as to identify key factors influencing CR referral in a Latin American context for the first time. The PACRR was translated into Brazilian-Portuguese through a rigorous process involving independent translation, back-translation, and expert panel review to ensure face, content, and cross-cultural validity. A total of 44 Brazilian physicians completed the questionnaire, allowing for an assessment of internal consistency, criterion validity, and convergent validity. The findings confirmed the face, content, and cultural validity of the 20 translated items, with a mean item clarity rating of 4.8/5. The final version included 17 of the original 19 PACRR-P items, with a Cronbach’s alpha of 0.73. Referral rates were significantly associated with specific PACRR-P items, supporting the scale's criterion validity, while correlations with ReCaRe scores further supported convergent validity. The most prominent barriers to referral were a lack of familiarity with CR site locations, absence of a standard referral form, and lack of automatic referral processes. The PACRR's validity and reliability among Portuguese-speaking providers are preliminarily supported.
Novel Compound Nonsense Variant in the CYP27B1 Cause an Atypical Form of Vitamin D-Dependent Rickets Type 1A: Case Report in Two Siblings in a Mexican Family
Authors: López Jaime Toral , Tenopala Cesar Candia , Mosqueda Daniela Reyes , Sánchez Miguel Ángel Fonseca , Huerta Luz María González
Published: September 2024

Vitamin D-dependent rickets type 1A (VDDR1A) is a rare autosomal recessive disorder, caused by pathogenic variants in the CYP27B1 gene, typically characterized by growth failure, rickets, leg bowing, fracture, seizures, hyperparathyroidism, hypocalcemia, high alkaline phosphatase, high or normal 25(OH)D3, and low 1,25(OH)2D3. We studied two siblings in a Mexican family with an atypical form of VDDR1A. In addition to the typical features of VDDR1A, the proband showed cafe au lait spots, small teeth and grayish sclera, with hypophosphatemia, normocalcemia and normal 25(OH)D3, the proband´s brother showed grayish sclera. Proband underwent Next Generation Sequencing. Sanger sequencing was performed in the proband, his brother, the parents and 100 healthy controls for validation of detected variant. Both brothers presented a recurrent variant NM_000785.3; c.1319_1325dupCCCACCC and a novel nonsense variant NM_000785.3; c.227G>A in the CYP27B1 gene. Calcitriol treatment had better response in proband´s younger brother. We describe the first Mexican family with an atypical form of VDDR1A associated with novel nonsense variant, the results contribute to the phenotypic spectrum and increases the pool of pathogenic variants in CYP27B1. Data suggesting that nonsense-truncating variants play a significant role in the severity of VDDR1A.
Unraveling the Heterogeneity of Deficiency of Mismatch Repair Proteins in Endometrial Cancer: Predictive Biomarkers and Assessment Challenges
Authors: Carvalho Filomena Marino , Carvalho Jesus Paula
Published: September 2024

Endometrial cancer (EC) poses a significant global health challenge, with increasing prevalence in 26 of 43 countries and over 13,000 deaths projected in the United States by 2024. This rise correlates with aging populations, the obesity epidemic, and changing reproductive patterns, including delayed childbearing. Despite the early diagnosis in 67% of cases, approximately 30% of cases present with regional or distant spread, leading to nearly 20% mortality rates. Unlike many cancers, EC mortality rates are escalating, outpacing therapeutic advancements until recently. One of the reasons for this was the lack of effective therapeutic options for advanced disease until recently. The introduction of immunotherapy has marked a turning point in EC treatment, particularly benefiting patients with defects in mismatch repair proteins (dMMRs). However, dMMR status alone does not ensure a favorable response, underscoring the need for precise patient selection. This review explores the pivotal role of mismatch repair proteins in EC, emphasizing their heterogeneity, the challenges in their assessment, and their potential as predictive biomarkers.
Solanum indicum Linn.: Bridging the Gap Between Traditional Knowledge and Modern Scientific Discoveries
Authors: Yadav Ritu , Tiwari Shashank
Published: September 2024

Solanum indicum Linn, is commonly known as Indian Nightshade or Poison Berry belongs to the family Solanaceae. This review studied the botanical description, traditional uses of its seeds, its chemical composition, pharmacological properties and modern applications in medicinal system. The plant is rich in alkaloids, steroidal saponins, flavonoids and phenolic acids having diverse pharmacological activities and phytochemical profile. It is used in treatment of various respiratory disorders, inflammation, skin problems and gastrointestinal disease since ancient times. Scientific research in modern times also tested many of the traditional uses revealing anti-inflammatory, antioxidant, antimicrobial activities as well as some cytotoxic and even antidiabetic effects. These pharmacological activities show potential future as uses for organic drugs, natural health products, skincare formulations and agricultural advancements.
Hallmarks of Brain Plasticity
Authors: Statsenko Yauhen , Kuznetsov Nik V. , Ljubisavljevic Milos
Published: September 2024

Brain plasticity is the ability of the brain to change and adapt in response to experience or learning. Its hallmarks are developmental flexibility, complex interactions of genetic and environmental influences, and structure-functional changes comprising neurogenesis, axonal sprouting, and synaptic remodeling. Herein, we review brain plasticity association with non-coding RNAs (ncRNAs). Studies on brain plasticity have important practical implications. Numerous cerebral ncRNAs are linked with neurological disorders, which makes them putative targets for RNA-based diagnostics and therapeutics since molecular characteristics of brain plastic change may reveal disease course and rehabilitative potential of the patient. A new insight into the concept of brain plasticity will provide perspectives on functional recovery following brain damage. The knowledge of this phenomenon will enable physicians to exploit cerebral plastic potential and regulate eloquent networks with timely interventions. Future studies will provide pathophysiologic mechanisms of brain plasticity at macro- and microscopic levels to advance rehabilitation strategies and improve the quality of life in neurological disorders.
Exploring the Impact of Environmental Conditions and Bioreactors on Microalgae Growth and Applications
Authors: Do Sally , Du Zhi-Yan
Published: September 2024

Microalgae and their bioproducts hold significant potential across various applications, for instance, in wastewater remediation, CO2 fixation, and the synthesis of nutraceuticals, pharmaceuticals, and biofuels. The production of these organisms heavily relies upon environmental conditions, including factors like temperature, light, and nutrient supply, which can significantly impact growth. Furthermore, the limitations in nutrients or certain extreme environments can result in productivity increases. As such, microalgae growth systems have become a critical consideration for both research and industry. Both open and closed systems, such as raceway ponds and photobioreactors, respectively, have their own advantages and drawbacks in microalgae cultivation. However, for microalgae growth, photobioreactors may address most concerns, as the system has a lower risk of contamination and can deliver specific growth factors in a controlled manner. This review will summarize the growth and incubation factors of microalgae and the uses of bioreactors in both research and industrial capacities.
The Role of Copper in Alzheimer’s Disease Etiopathogenesis: An Updated Systematic Review
Authors: Sabalic Angela , Mei Veronica , Solinas Giuliana , Madeddu Roberto
Published: September 2024

Background: Alzheimer's disease (AD) is the most common cause of dementia and cognitive decline in the elderly. Although the etiology of AD is unknow, the increase of amyloid precursor protein (APP) leads to the toxic aggregation of Aβ plaques. Several factors such as hypertension, diabetes, dyslipidemia, smoking, hormonal changes, and metal exposure could increase the risk of developing AD.
In this review, we will examine the role of copper (Cu) in the pathophysiology of AD, as well as the mechanisms involved in neurotoxicity and cognitive decline.
Methods: This review was conducted in accordance with PRISMA guidelines. We performed a comprehensive literature analysis of the last ten years on AD and Cu. Only late-onset Alzheimer’s disease was considered; therefore, only studies on elderly people of both sexes were included.
Results: A total of seven articles were picked for this review, three studies focused on non-ceruloplasmin bound Copper (non-Cp-Cu) and four on ceruloplasmin bound Copper (Cp-Cu). The results showed higher Cu concentrations in patients compared to healthy controls.
Conclusion: Elevated concentrations of Cu may contribute to the progression of AD, potentially interacting with ATP7B mutations, oxidative stress, and amyloid-β plaques. Future research is needed to provide more robust evidence and better characterize the relationships between AD and Cu.
Unlocking Supply Chain Visibility and Operational Efficiency: A Systematic Review of Industry 4.0 Technologies
Authors: Emon Md Mehedi Hasan , Khan Tahsina
Published: September 2024

Purpose: This systematic review investigates the implications of Industry 4.0 technologies on supply chain visibility and operational efficiency. The primary aim is to discern the impact of technological integration on contemporary supply chain dynamics. Design/Methodology/Approach: A comprehensive search strategy identified 67 pertinent studies published between 2015 and 2023. The review adheres to systematic methodologies, employing the Critical Appraisal Skills Programme framework for quality assessment. Data synthesis incorporates qualitative and quantitative analyses to distill key themes and patterns. Findings: The review unveils the pivotal role of information visibility in fortifying supply chain outcomes, emphasizing the need for a dual investment strategy encompassing technological solutions and a collaborative organizational culture. Regional variations in supply chain practices, insights from humanitarian supply chains, and the influence of environmental factors on agility broaden the understanding of Industry 4.0 implications. Research Limitations/Implications: The study acknowledges limitations in the geographical focus of the included studies and the evolving nature of Industry 4.0 technologies. These considerations prompt a call for ongoing research to capture emerging trends and global nuances. Practical Implications: Organizations are urged to adopt a context-specific, adaptive approach, recognizing the significance of intangible assets and tailoring strategies to local contexts for optimal supply chain performance. Originality/Value: This systematic review contributes a nuanced understanding of Industry 4.0's transformative potential in supply chain management, emphasizing the interplay between technology, organizational culture, and regional contexts.
Development of Slow-Release Fertilizers with Function of Water Retention Using Eco-Friendly Starch Hydrogels
Authors: Song Yue , Ma Litao , Duan Qingfei , Xie Huifang , Zhang Huaran , Dong Xinyi , Yu Long
Published: September 2024

Various slow-release fertilizers (SRFs) have been developed and commercialized, particularly over the past two decades, with the primary aim of mitigating environmental issues associated with excessive fertilizer use. A range of methodologies, including chemical and physical reactions, incorporation into carriers with porous and layered structures, and coating techniques, have been explored and refined. On the other hand, dry and desertification are big challenges for agriculture in many countries in the world. Application of hydrogels or superabsorbent polymers as carrier materials to develop SRFs could add the function of moisture retention. This paper reviewed the development of application eco-friendly starch hydrogels as fertilizer carrier and water retention to develop SRFs, in particular starch-based superabsorbent polymers through grafting copolymerization with acrylamide. The reviewer includes both scientific issues like general microstructures of various starch hydrogels and releasing mechanisms, and technical development involving copolymerization technologies, multi-initialization and loading fertilizer into hydrogel etc. Starch, recognized as one of the most abundant carbohydrate polymers, is both biodegradable and renewable. It exhibits excellent chemical stability and high reactivity. The fabrication technique of starch hydrogels though grafting polymerization have been developed from batch chemical reaction in aqueous solution to high efficient and no-solvent reactive extrusion. The benefits of SRFs based on starch hydrogel encompass enhanced soil aeration, prevention of soil deterioration, minimization of water evaporation, environmental pollution control, reduction in plant mortality, and prolonged nutrient retention within the soil. Based on the literatures and our experience, we have not only discussed and summarized the achievements, but also pointed out the weakness of current technologies and proposed research directions in this review.
Comparison of CNN-Based Architectures for Detection of Different Object Classe
Authors: Bilous Nataliya , Malko Vladyslav , Frohme Marcus , Nechyporenko Alina
Published: September 2024

Detecting people and technical objects in various situations, such as natural disasters and warfare, is critical to search and rescue operations and the safety of the civilian. A fast and accurate detection for people and equipment can significantly increase the effectiveness of search and rescue missions and provide timely assistance to people. Computer vision and deep learning technologies play a key role in detecting the required objects due to their ability to analyse big volumes of visual data in real time. The performance of the neural networks such as YOLOv4-v8, Faster R-CNN, SSD, and EfficientDet has been analysed using COCO2017, SARD, SeaDronesSee, and VisDrone2019 datasets. Main criteria for comparison were mAP, Precision, Recall, F1-Score, and the ability of the neural network to work in real time. The most important metrics for evaluating the efficiency and performance of models for a given task are accuracy (mAP), F1-Score, and processing speed (FPS). These metrics allow us to evaluate both the accuracy of object recognition and the ability to use the models in real-world environments where high processing speed is important. Although different neural networks perform better on certain types of metrics, YOLO outperforms them on all metrics, showing the best results of mAP-0.88, F1 - 0.88, and FPS - 48, so the focus was on these models.
Development and Characterization of Paclitaxel-Loaded Li-pid-Coated Mesoporous Silica Nanoparticles for pH-Responsive Tumor-Targeted Drug Delivery
Authors: Yingyue Deng , Jiaru Zhou , Tao Zhang , Guoqiang Wang , Min Xiao , Junfeng Ban , Yan Zhang , Hongcai Liang
Published: September 2024

Nanoparticle carriers can selectively deliver the drug cargo to tumor cells, thus having the ability to pre-vent early drug release, reduce non-specific cell binding, and prolong in vivo drug retention. We con-structed paclitaxel (PTX)-loaded lipid-shell mesoporous silica nanoparticles (LMSNs) for targeted an-ti-cancer drug delivery. The physical properties of PTX-LMSNs were analyzed by scanning electron mi-croscopy (SEM) and transmission electron microscopy (TEM). The drug loading (DL%) and entrapment efficiency (EE%) of PTX-LMSNs were measured by high performance liquid chromatography (HPLC). In vitro drug release test, in vivo imaging, tissue distribution and pharmacokinetics of PTX-LMSNs were also evaluated. The SEM examination showed that MSNs were sphere, whereas TEM showed that they were rich in fine pores. The uniform core-shell structure of PTX-LMSNs was also verified by TEM. The DL capacity of PTX-LMSN was as high as 21.75%, and PTX was released from the nanoparticles in vitro in a pH-dependent manner. The cumulative amount of free PTX increased at lower pH, which is conducive to selective drug release from LMSNs in the acidic tumor tissues. In vivo imaging showed prolonged reten-tion of PTX-LMSNs, which is beneficial to their therapeutic efficacy. In addition, PTX-LMSNs were primarily concentrated in the liver. Pharmacokinetic experiments showed that the half-life of PTX-LMSNs was 23.21% longer and 79.24% higher than that of Taxol. Together, LMSNs are a highly promising antineoplastic drug carrier system.
Individual and Community‐Level Determinants of Knowledge of Obstetric Danger Signs among Women in Southern Ethiopia: A Multi‐Level Mixed Effect Negative Binomial Analysis
Authors: Yoseph Amanuel , Simachew Yilkal , Tsegaye Berhan , Borsamo Asfaw , Seifu Yohans , Mehretu Mehretu
Published: September 2024

Introduction: One of the key strategies to achieve sustainable development goal by reduce preventable maternal deaths below 70 per 100,000 is increasing awareness about major obstetrics danger sign. Mother's awareness of obstetric danger signs in developing country is relatively low regardless of attempts trough many local and national program. It is crucial to increase women’s knowledge of obstetric danger signs through education and awareness-raising efforts. Despite its importance to reduce maternal deaths, Studies are limited only to the Northern Ethiopia. Objective: This study aimed to assess prevalence of knowledge of obstetric danger signs and associated factors among women who delivered in the last 12 months in Sidama region, Ethiopia. Methods: We conducted a community-based cross-sectional study from October to November, 2022. A multi-stage sampling procedure was utilized to select study participants. A structured and pretested questionnaire was utilized to collect data. A multilevel mixed-effects negative binomial regression model was used to control effects of clusters and confounders.Results: Out of 1,140 study participants, only 1,130 study participants took part in the study making a response rate of 99.12%. The overall prevalence of knowledge of obstetrics danger sign was estimated as 22.3% (95%CI: 18.7, 25.9). Government employed women (AIRR = 1.37; 95% CI: 1.2, 1.6), women who had access to mass media (AIRR = 1.16; 95% CI: 1.08, 1.25), women who had received model family training (AIRR = 1.15; 95% CI: 1.1, 1.25), autonomous women (AIRR = 1.15; 95% CI: 1.04, 1.25), women who had faced health problems during pregnancy (APR = 1.21; 95% CI: 1.11, 1.32) and urban women (APR = 1.22; 95% CI: 1.09, 1.62) were factors associated positively with knowledge of obstetrics danger sign. Conclusion: The prevalence of knowledge of obstetrics danger sign is found to be lower compared with the national average. Residence, mass-media exposure, model family planning, problem faced during pregnancy and women autonomy are the main predictors of knowledge of obstetrics danger sign. Public health policy makers should enhance health literacy at for focused on rural community. Awareness creation should be improved through mass media. Health providers should educate women during maternity health services to empower women for decision making process.
Mental Health Attitudes and Perspectives of an Arab American Community: Beliefs Associated with Stigma, Treatment, and the Origins of Pathology
Authors: Browning Liam , Oska Nicole , Kidess George , Hinchey Liza , Saleem Arwa , Knill Sadie , Elhage Malaak , Javanbakht Arash
Published: September 2024

Purpose: Arab Americans are one of the largest ethnic groups in the United States. The mental health of Arab Americans and opinions on mental health, however, remain understudied despite higher rates of mental illness and lower rates of treatment. Unique cultural conceptualizations of mental illness may generate stigma, contributing to disparities in treatment. This study aimed to assess the attitudes and perspectives of Arab Americans regarding mental illness in order to address barriers to treatment. Methods:Using an anonymous bilingual Qualtrics survey, we assessed Arab and non-Arab participants (n = 294; ages 18+) on their conceptualizations of the causes of mental illness and on their stigma towards mental illness and mental health treatments. Comparisons were performed between Arabs and non-Arabs, as well as among Arabs. Results:Compared to non-Arabs, Arabs reported higher average mental illness stigma and were more likely to rate psychiatric medications as addictive and unhelpful. Among Arabs, being Christian, male, and older (>29 years old) were each associated with higher stigma. Arabs were less likely than non-Arabs to believe in a biological explanation for mental illness. Conclusion: Our results demonstrate higher levels of stigma towards mental illness among Arab Americans, especially Christian, male, and older Arabs, potentially related to a weaker belief in a biomedical model for mental illness. These are among the first findings describing mental illness stigma and beliefs about mental health in an Arab American community and may inform future interventions providing culturally competent care to Arab Americans.
The Economic Impact of Post-Traumatic Stress Disorder Among Patients with Systemic Autoimmune Diseases During the COVID-19 Pandemic
Authors: Lorenzoni Valentina , Andreozzi Gianni , Palla Ilaria , Tani Chiara , Carmassi Claudia , Fulvio Giovanni , Trentin Francesca , Fantasia Sara , Conti Lorenzo , Dell'Osso Liliana , Mosca Marta , Turchetti Giuseppe
Published: September 2024

Background: The present work aimed to estimate the economic impact of PTSD following COVID-19 in a population of patients affected by systemic autoimmune disease (SAD) using a cost-of-illness approach and accounting for the perspective of society. Methods: Considering data collected from SAD patients enrolled in a specialized outpatient clinic in the Tuscany region, Italy, generalized-linear-models and LASSO logistic regression were used to evaluate the impact of PTSD on costs and its relevance as possible predictors of being a high-cost patient, respectively. Results: Considering 301 SAD patients, 161 (51.2%) of whom diagnosed with PTSD, the overall costs were 3,670 [890;40,529] Euro per patient/year among patients with PTSD and 2,736.7 [283;21,078] Euro per patient/year among those without PTSD (P-value<0.001), with differences mainly attributable to significantly greater direct non-healthcare and indirect costs. PTSD was estimated to increase overall costs (β=0.296 (0.140), P-value=0.035), direct non-healthcare (β =1.193 (0.392), P-value =0.002) and indirect costs (β =3.741 (1.136), P-value =0.001). PTSD diagnosis was also significantly associated with the likelihood of being a high-cost patient. Conclusions: Findings from the present study offer a novel perspective on the economic impact of COVID-19 and provide valuable data for policymakers to better understand demand for healthcare services and associated costs.
The Impact of Parental Depression, Anxiety, and Stress on Adolescents’ Mental Health and Quality of Life: The Moderating Role of Parental Rejection
Authors: Sofrona Eirini , Giannakopoulos Georgios
Published: September 2024

Background/Objectives: Parental internalizing issues, particularly maternal mental health, can significantly influence adolescents' mental health by altering parenting behaviors and roles. This study aims to explore how parental rejection, a dimension of both maternal and paternal behavior, moderates the relationship between parental depression, anxiety, and stress with adolescents' mental health and quality of life. We hypothesized that parental rejection would have a significant moderating effect on these relationships; Methods: This cross-sectional, non-interventional study involved 206 parents (138 mothers) of adolescents aged 12-18 years from the general population. Participants were recruited online via convenience sampling and completed the Depression Anxiety Stress Scale (DASS), the Parental Acceptance-Rejection Questionnaire, the KIDSCREEN-27 to evaluate adolescents' quality of life, and the Strengths and Difficulties Questionnaire to assess adolescents' mental health; Results: Parental rejection was found to moderate the relationship between maternal anxiety and adolescents' quality of life, as well as between maternal anxiety and adolescents' mental health problems. Paternal rejection moderated the relationship between paternal stress and adolescents' mental health. However, parental rejection did not moderate the relationship between parental depression and adolescents' quality of life or mental health; Conclusions: These findings emphasize the significant role of maternal rejection in the association between maternal mental health, particularly anxiety, and adolescents' mental health outcomes. Paternal rejection also showed some moderating effects, though to a lesser extent. These results underscore the importance of considering both maternal and paternal influences in adolescent mental health and quality of life. Further research is necessary to fully understand the gender-specific dynamics of these relationships.
The structure of errors in recognizing the author of the text by the trigram method
Authors: Kislitsyna Maria Yurievna , Orlov Yurii Nikolaevich
Published: September 2024

Statistics of reference trigrams for the complete corpus of literary texts in Russian, including translated foreign authors, have been collected. Distributions of distances from individual texts to standards are constructed. The nearest reference method for recognizing the author of the text has been tested. The error was determined by genres, subgroups of authors and by the corpus as a whole. A classification of errors has been carried out to develop a correction method.
Kesesuaian Lokasi Terminal Jalan Sutra di Kabupaten Boyolali
Authors: Dhaniati Titin Putri , Andini Isti , Mukaromah Hakimatul
Published: September 2024

Sistem transportasi memiliki peran dalam mengakomodasi kebutuhan mobilitas penduduk yang terus berkembang. Dalam keberhasilan pembangunan wilayah serta pertumbuhan ekonomi, sistem transportasi juga berperan sebagai katalisator penggerak pembangunan. Terminal merupakan salah satu komponen transportasi yang berfungsi sebagai sarana transportasi publik yang serbaguna untuk melayani kebutuhan dalam mengakses seluruh wilayah perkotaan. Untuk menciptakan terminal yang memiliki dampak signifikan terhadap perkembangan wilayah, Peraturan Menteri Perhubungan Nomor 24 Tahun 2021 menetapkan karakteristik lokasi ideal dalam penetapan lokasi terminal penumpang. Pemerintah Kabupaten Boyolali melakukan relokasi terminal tipe B dari Terminal Induk Sunggingan ke Terminal Jalan Sutra. Namun, lokasi Terminal Jalan Sutra yang dianggap sebagai titik pertumbuhan ekonomi, ditengarai tidak mampu meningkatkan pertumbuhan ekonomi wilayah sekitar. Oleh karena itu, penelitian ini dilakukan untuk menilai kesesuaian lokasi terminal tipe B di Kabupaten Boyolali, yaitu Terminal Jalan Sutra tersebut. Variabel penelitian meliputi aksesibilitas, kesesuaian terhadap Rencana Tata Ruang Wilayah (RTRW), keterhubungan dengan jaringan trayek angkutan umum, keterhubungan dengan jaringan jalan, kesesuaian kinerja lalu lintas, ketersediaan lahan, dan kelestarian lingkungan. Penelitian dilakukan dengan analisis kuantitatif dengan teknik analisis skoring dan pembobotan. Berdasarkan hasil penelitian, diketahui bahwa lokasi Terminal Jalan Sutra memiliki nilai kesesuaian sebesar 2,53 dari total skor kesesuaian 3,13 yang artinya lokasi Terminal Jalan Sutra dinyatakan sesuai terhadap prasyarat lokasi terminal penumpang tipe B. Berdasarkan hasil penilaian kesesuaian, lokasi Terminal Jalan Sutra memiliki kesesuaian terhadap aksesibilitas (indikator waktu tempuh, biaya atau ongkos perjalanan, pendapatan pelaku perjalanan, dan jarak), kesesuaian dengan RTRW, keterhubungan dengan jaringan trayek angkutan umum (jaringan trayek angkutan umum Antar Kota Dalam Provinsi/AKDP, jaringan trayek angkutan perkotaan, dan jaringan trayek angkutan perdesaan), keterhubungan dengan jaringan jalan (fungsi dan kelas jalan, rencana pengembangan jalan), dan terhadap kesesuaian lalu lintas, serta kelestarian lingkungan.
PROBLEMS OF MANAGING THE IMMUNE RESPONSE UNDER CONDITIONS OF COMPETITIVE ADSORPTION, DIFFUSION PERTURBATIONS AND TEMPERATURE RESPONSE OF THE ORGANISM
Authors: Baranovsky Serhii Vitaliiovych
Published: September 2024

Analysis of the problems associated with the rapid spread of infectious diseases indicates the need for new approaches to the diagnosis and develop- ment of effective personalized treatment programs. One of the important aspects of solving this problem is the creation of a mathematical modeling toolkit for predicting the dynamics of infectious diseases, taking into account spatial effects, concentrated effects, various mechanisms of body protec- tion in the conditions of the application of various types of therapeutic methods of treatment. An important component of complex methods of treat- ment of a wide range of infectious diseases is the use of adsorption drugs, which, along with detoxification of the body, are able to provide an addi- tional mechanism of neutralization of viral elements. In the process of using such means, not only pathogenic elements and toxins will be adsorbed, but also various types of immune agents, which will affect the dynamics of the immune response. In the paper the infectious disease model is generalized to take into account the features of competitive adsorption of antigens and immune agents in the conditions of diffusion perturbations, concentrated influences and temperature reaction of the body. By synthesizing the ideas of step-by-step procedures, asymptotic and numerical methods, an effective computational technology of step-by-step approximation of the solution of the original model singularly perturbed problem was built. The results of the computer experiments presented in the paper illustrate the features of reducing the predicted concentration of viral elements during their competi- tive adsorption together with immune agents, in particular, the effect of reducing the efficiency of the use of non-specific adsorbents. It is emphasized that taking into account the features of the action of competitive adsorption is important for making decisions regarding the formation of rational treatment programs with the complex use of adsorbing substances and immunological drugs.
Analisis Kualitas Permukiman Berbantuan Google Earth di Desa Sungai Kedukan, Kabupaten Banyuasin, Sumatra Selatan
Authors: Ruzaina Urwa , Eni Heldayani  , Mirna Taufik
Published: September 2024

The river basin settlement in Sungai Kedukan Village is a settlement located along the river and has an area of approximately 300,000 m2 with RT boundaries covering 8 RTs along the Nibung River, Sungai Kedukan Village with a background of the problem of residential building density where the condition of the buildings is very close together because of the large number of residents living in the settlement, irregular building layout, and lack of facilities and infrastructure. The purpose of the study was to determine the quality of settlements assisted by Google Earth in Sungai Kedukan Village, (DAS), Rambutan District, Banyuasin, South Sumatra. This study uses a quantitative approach with a survey method that has a population and sample using purposive sampling with data processing using the Google Earth application and to conduct analysis, namely by entering formulas from building density parameters, building layout, road width, and access road conditions, as well as by collecting questionnaires to determine the quality of the residential environment. This study shows that the quality of settlements and residential environments in river basin areas produces the same results and is included in various categories, namely poor and moderate.
Optimization strategies for geospatial data on end-user devices
Authors: Ruby Jeffrey , Fischer Robert , Massaro Richard , Pham Melissa , Luke Robert , Camaioni Raub , Wilson David , Frantz Nathan , Lin Christina , Shuart William , Anderson John
Published: September 2024

The ability to quickly disseminate geospatial data across all echelons, particularly those at the tactical edge, is critical to meeting threats described by the Multi-Domain Operations doctrine. The US Army Engineer Research and Development Center, Geospatial Research Laboratory (ERDC-GRL), is researching the optimization of the formats, data models, file sizes, and quality of geospatial products to be exploited by end-user devices (EUDs). This report describes a processing methodology comprising custom software and open-source tools to optimize Army Geospatial Enterprise Standard Sharable Geospatial Foundation and industry-accepted products for exploitation on EUDs. The Integrated Visual Augmentation System (IVAS) was emphasized, but other devices, including the Nett Warrior and Program Executive Office—Soldier targeting systems, were also studied. Additionally, we developed a compression methodology that reduced the size of three-dimensional model data by a factor of 9 without a loss in data quality. A summary of the results describes steps to address remaining technical issues and considers future efforts to further optimize geospatial data for additional EUDs and tactical applications.
Selection of internal design of crystallizer sleeves for continuous casting of 200 mm billets
Authors: Bondarenko I. A. , Volodkin P. V. , Kovaleva I. A.
Published: September 2024

The crystallizer is the most critical and most important functional unit of a continuous casting machine (hereinafter referred to as CCM). It is the main technological unit of the CCM, an assembly for removing heat during the solidification of the solidifying metal and the formation of the ingot. The main requirement for the crystallizer is to provide maximum heat removal from the solidifying steel to the cooling water, and to obtain a strong ingot shell with a good surface at the outlet of the crystallizer, which would not be destroyed by the heat of the liquid phase and the ferrostatic pressure. During the reconstruction of the CCM by the contractor company, drawings of crystallizers and crystallizer sleeves with a double‑cone internal geometry for casting 200 mm continuous cast billets were developed. The 200 mm continuous cast billet is a billet for the production of hot‑rolled seamless steel pipes. During the operation of the crystallizer sleeves with a double‑cone internal geometry, an accelerated wear of the protective coating in the lower part of the sleeve was noted, as well as an increased rejection of hot‑rolled pipes due to defects on the outer surface of the pipes. In order to identify the cause of the defect formation, complex metallographic studies of the outer surface of the pipes were carried out. As a result of the metallographic study, surface defects classified as steel mill scale on the outer surface of the pipes were identified. To minimize the “steel mill scale” defect and reduce the wear of the protective coating of the crystallizer sleeves, work was carried out to select the optimal conditions for the crystallization of the continuous cast billet: the use of crystallizer sleeves with a three‑cone internal geometry compared to a double‑cone was investigated; maintaining the temperature difference of the water at the inlet and outlet of the crystallizer within specified limits (ΔT) was tested. It was found that the use of a crystallizer sleeve with a three‑cone internal geometry for casting 200 mm billets and the stable behavior of the ΔT parameter made it possible to ensure the required quality of the surface of seamless pipes, reduce the wear of the protective coating of the crystallizer sleeves and increase the productivity of the CCM.
The influence of structure dispersity on the intensity of hardening during tensile testing of pearlitic steel
Authors: Fetisov V. P.
Published: September 2024

During uniform and concentrated stretching of thin‑plate pearlite steel, a comparison of the structural dependence of strength and plastic properties, indicators of hardening intensity in the form of the degree of relative strength increase and the rate of deformation hardening, was carried out. Increased structural sensitivity is characteristic of the fracture stress, uniform relative contraction, and the degree of relative strength increase. It is recommended to evaluate the contribution of the deformation hardening intensity to the formation of the ductility of pearlitic steel by the parameters of the relative strength increase.
Control of properties of core mixes manufactured by Cold‑box‑amineprocess
Authors: Kulikov S. A. , Rudnitsky F. I. , Shumigay V. A. , Kulikov Yu. A.
Published: September 2024

The article considers the strength issues of foundry cores manufactured by the Cold‑box‑amine process. It is shown that the properties of the core mix can be controlled by adjusting the formulation. Examples of the influence of binders’ consumption on the properties of the mixes are given: a decrease in resin and polyisocyanate leads to a decrease in strength and a decrease in life. In addition, the minimum consumption of binders varies from manufacturer to manufacturer. Recipes of mixes with special additives are given, which allow, by reducing the strength of the mix, to ensure the completeness of the polymerization reaction.
Secondary transformations in the structure of grey cast iron
Authors: Marukovich E. I. , Stetsenko V. Yu. , Stetsenko A. V.
Published: September 2024

A nanostructural mechanism of secondary transformations in the structure of gray cast iron is proposed. First, structureforming nanocrystals of austenite, ferrite, cementite and graphite are formed from elementary nanocrystals of iron and graphite, free atoms of iron and carbon. The crystallization centers of microcrystals of phases are formed from them. From these centers, structure‑forming nanocrystals of phases, free iron and carbon atoms, microcrystals of austenite, ferrite, cementite and graphite of binary gray cast irons are formed.
The influence of acid treatment on the adsorption‑structural characteristics of filtering materials created based on steelmaking slag
Authors: Panasyugin A. S. , Tsyganov A. R. , Masherova N. P. , Pavlovsky N. D. , Lomonosov V. A.
Published: September 2024

Many industrial enterprises use electroplating processes that lead to the formation of water containing heavy metal ions such as chromium, copper, zinc, nickel, and others. Such water is a dangerous source of environmental pollution. Most heavy metal ions belong to hazard classes I–II, they have carcinogenic and mutagenic properties, and have a cumulative effect.

The literature analysis showed that there is positive experience in the use of steelmaking slags in the processes of cleaning contaminated water of various origins from heavy metals.

The study examines the effect of acid activation on the adsorption‑structural characteristics of filtering materials created based on steelmaking slag. It is shown that during the interaction of some acids with slag, new crystallographic phases are formed

on its surface, and contact with other acids leads to the leaching of ions and their transition to the aqueous phase. It has been established that during acid activation, the specific surface area increases by 57–132 times compared to the original material.
ANÁLISIS ENERGÉTICO DE UNA BOMBA DE CALOR MODIFICADA. COMPARATIVO ENTRE SISTEMA SIMPLE, CON REFRIGERACIÓN, Y CON ORC.
Authors: Hernández Magallanes Javier Alejandro , De Santiago Diana , Cerdán Andrea , Kozhiparambil Sanal , Lugo Shadai , Jiménez Camilo
Published: September 2024

El presente estudio muestra un análisis energético comparativo de tres sistemas avanzados de poligeneración. En primer lugar, se expone un sistema base que sirve como punto de referencia, Ciclo I (potencia-calentamiento) (Figura 1a). Luego, se introducen modificaciones para incorporar el efecto de refrigeración, Ciclo II (Figura 1b), y finalmente se aumenta la producción global de potencia añadiendo un Ciclo Orgánico de Rankine ORC, Ciclo III (Figura 1c). Para  analizar los sistemas propuestos, se llevaron a cabo diversos estudios paramétricos, abarcando una variedad de aspectos como los niveles de temperaturas, la relación de presiones, la relación de flujos másicos, y las cargas térmicas, entre otros. Con los resultados obtenidos se examinaron los parámetros energéticos ηth, ηIeff, y ratio de los sistemas propuestos. Como valores promedio, para los ciclos I, II y III, se obtuvieron valores de eta_th de 0.53, 0.46 y 0.58; eta_I,eff de 0.14, 0.15 y 0.07; y ratios de 0.07, 0.17 y 0.25, respectivamente. Con los resultados obtenidos se muestran tres propuestas energéticas alternativas que funcionan con temperaturas bajas de operación (150 °C) para producir potencia-calor revalorizado, y enfriamiento.
EVALUATION OF THE USE OF RADIATIVE COOLING TECHNOLOGY TO SUPPORT THE AIR CONDITIONING SYSTEM OF A DATA CENTRE
Authors: Cofré-Toledo Jonathan , Vilà Roger , Castell Albert , Martorell Ingrid
Published: September 2024

Data centre space cooling systems consume a lot of energy and will increase over the years. Therefore, it is necessary to propose new refrigeration strategies. Radiative cooling (RC) production is a renewable alternative solution with a promising future. In this work, the energy modelling of the air conditioning system of a data centre coupled to a RC emitter is carried out to explore the benefits of this technology. The system consists of a water chiller connected to a cooling coil through which air is circulated for distribution in the data centre room. The simulations were carried out for a typical summer week in Barcelona. The RC production was carried out during the night, and this power was used during the day and was implemented directly in the energy balance of the data centre room, considering emission surfaces of 80 and 60% of the total building roof, reducing the water chiller energy consumption by 13 and 10% respectively. In the transient behaviour of the temperature in the data centre room, when the RC was used to reduce the peak cooling load, a reduction of the temperatures was observed approaching to the design setpoint, therefore, the IT equipment was not affected.
EL USO DE ACEITE DE OLIVA ENCAPSULADO Y VINAGRE EN POLVO ENCAPSULADO, EN LA FORMULACIÓN DE ALIMENTOS EMPANADOS REFRIGERADOS, TIENE UN EFECTO SINÉRGICO EN EL AUMENTO DE SU VIDA ÚTIL
Authors: Martínez Sánchez María Ángeles , Barón Yusty Marta , López Gómez Antonio , Martínez Hernández Ginés Benito
Published: September 2024

Los alimentos empanados refrigerados (conservados a 4 ºC), como las croquetas, los nuggets y los filetes de carne y pescado empanados, tienen una vida útil relativamente corta, de sólo 8 días, lo que impide que los productos fabricados en España puedan comercializarse en otros países europeos. Para ello, se requiere una vida útil de al menos 15 días cuando se almacenan refrigerados a 4 ºC. Por ello, se han investigado diferentes técnicas para aumentar su vida útil. Una de ellas ha sido la utilización de aceite de oliva virgen extra (AOVE) encapsulado en alfa-ciclodextrina, mezclándolo con el pan rallado. De esta forma, se consigue un aumento significativo de la vida útil, hasta 14 días. En este trabajo se ha estudiado el posible efecto sinérgico del uso simultáneo de vinagre en polvo encapsulado (en la formulación del núcleo de las croquetas) con AOVE encapsulado (mezclado en el pan rallado). La vida útil se ha evaluado determinando la evolución del recuento microbiano en este producto (aerobios mesófilos totales, enterobacterias, bacterias lácticas, psicrófilos y mohos y levaduras). Con esta nueva tecnología se ha conseguido aumentar la vida útil de las croquetas hasta superar los 21 días, envasadas en bandejas con atmósfera modificada (MAP) y almacenadas a 4ºC.