bluuebunny/crossref_metadata_2025 huggingface dataset:
Suplementação com vitamina D no controle da asma – revisão integrativa
Authors: Trombim Luan Cordeiro , Costa Sérgio Marques , Suter Lucas Manetta da Cunha , Leme João Guilherme Catarino Pereira , Dantas Daniel Antonio Rissi , Silva Debora Tavares de Resende e , Salge Ana Karina Marques , Medeiros Mariana Figueiredo Corrêa de , Cavalcante José Rafael Assad , Costa Graziela Beatriz  Caseiro , Blanco Gabriela Reigota , Rossi Renata Calciolari
Published: February 2022

Atualmente a deficiência de vitamina D tem sido reconhecida como uma pandemia causadas por múltiplos fatores. Um número cada vez maior de estudiosos tem voltado seus esforços para pesquisas relacionadas aos efeitos adversos da deficiência da vitamina D e sua possível associação com patologias, tais como a asma. Poucos trabalhos foram publicados com avaliações diretas sobre o papel da vitamina D na asma, mas existem pesquisas que relacionam indiretamente esta vitamina com mecanismos da doença. Este manuscrito é uma revisão integrativa que utilizou o método PICO (população, intervenção, comparação, resultado) para a seguinte pergunta: “A suplementação com vitamina D ajuda no controle da asma?” Foram incluídos na população de estudo, asmáticos, sem outras comorbidades; a intervenção foi a suplementação com vitamina D e a comparação com indivíduos não suplementados, resultado analisado foi se houve ou não melhora do controle da asma. Em conclusão, altas doses de suplementação com VD, associado ao tratamento padrão da asma, podem melhores os parâmetros de controle da doença, apesar que mais estudos são necessários sobre o tema.
Administração de recursos humanos no setor público
Authors: Santos Viviane Rodrigues Sales dos , Corrêa Alessandra Conceição Santos
Published: February 2022

Este trabalho tem como proposta entender o funcionamento da Administração de Recursos Humanos no Setor Público. A metodologia utilizada foi a pesquisa bibliográfica. A administração pública tem por objetivo principal atender ao interesse público e às necessidades sociais. Para o cumprimento da sua função administrativa, o Estado possuí certas prerrogativas lhe asseguradas por lei; contudo, tais prerrogativas precisam ser utilizadas no cumprimento das ações que foram propostas em sua criação. Na administração pública, administrar vai além de executar serviços públicos, mas direcionar e gerenciar buscando o bem e a satisfação da sociedade. A literatura a respeito de gestão de pessoas na área privada é bastante ampla, no entanto, aquela específica para a área pública é escassa e dispersa. Por um longo período, a gestão de pessoas na área pública tinha como foco principal a realização de atividade operacional, não havendo instruções claras sobre as diretrizes que regiam os recursos humanos. A falta de capacitação e de participação da equipe se perderam devido à falta de objetivos, pois elevado é o nível de comprometimento que exige a mudança, onde muitas das vezes não são vistas como melhoria, mas perca de tempo.
Boas práticas executadas pela enfermagem ao paciente submetido a revascularização miocárdica
Authors: Lins Rodrigo de Albuquerque , Aredes Kézia Verli Nunes , Fassarella Bruna Porath Azevedo , Santos Larissa Christiny Amorim dos , Souza Francine Silva de , Lima Dayene Rodrigues de , Ribeiro Wanderson Alves , Neves Keila do Carmo , Alves Ana Lúcia Naves , Amaral Fernando Salgado do
Published: February 2022

Objetivo deste estudo é elucidar através da literatura científica as boas práticas de enfermagem na revascularização do miocárdio. A pesquisa foi de natureza descritiva realizada através de revisão bibliográfica, realizada na base de dados por meio da Biblioteca Virtual em Saúde (BVS), a qual abrange: LILACS, BDENF, Google acadêmico e SCIELO, através dos descritores: Boas práticas, enfermagem e infarto agudo do miocárdio. Os critérios de inclusão foram: obras publicadas na íntegra, em língua portuguesa, publicados nos últimos 10 anos e que possuam aderência ao tema, na qual foram utilizados 21 artigos para construção deste estudo. Compreende-se que, o pós-operatório imediato dos pacientes submetidos à cirurgia cardíaca acontece em Unidade de Terapia Intensiva (UTI), visto que, é um setor que promove recursos suficientes para atender a paciente de alta complexidade, como os que realizam alguma cirurgia cardíaca. Logo, foi possível observar o pós-operatório imediato de pacientes submetidos a revascularização do miocárdio, e a importância da sistematização da assistência de enfermagem como uma tônica na eficácia dos cuidados através do planejamento e preparo seguro, para que toda a equipe a equipe envolvida no processo realize uma abordagem individual e integral ao paciente.
City Information Modeling como ferramenta na gestão urbana: aplicação da integração GIS-BIM
Authors: Melo Francisca Ires Vieira de , Giesta Josyanne Pinto , Queiroz Luiz Alessandro Pinheiro da Camara de
Published: February 2022

Os centros urbanos vêm se tornando ambientes cada vez mais complexos, ocasionando mudanças que se expressam tanto na paisagem da cidade como no comportamento e estilo de vida das pessoas, causando, dessa forma, transformações que impactam diretamente na estruturação socioespacial urbana. Deste modo, esse artigo apresenta parte dos resultados de uma pesquisa de mestrado, possuindo o objetivo de elaborar diretrizes para a integração de softwares GIS-BIM, com intuito de facilitar a tomada de decisões no planejamento urbano. Para isso, será abordado o método de pesquisa Design Science Research (DSR) com a utilização de artefatos destinados a sanar problemas do mundo real. Apresenta-se abordagens de integração GIS-BIM, por meio da compatibilização do georreferenciamento e da modelagem de um bairro da cidade de Pau dos Ferros/RN - Brasil. Como resultados desenvolveu-se uma proposta com diretrizes de integração GIS-BIM e por meio da aplicação da mesma foi possível obter a modelagem total do bairro com 1.496 edificações modeladas, onde os parâmetros de gabarito, área construída e área de projeção da edificação podem ser extraídos de forma automática. O desenvolvimento dessa integração contribui na redução do custo de tempo e de recursos para produzir informações geográficas, além de facilitar a visualização e compreensão do território estudado.
Análise Bioética frente a Covid-19: abordagem necessária para a área da saúde
Authors: Camacho Alessandra Conceição Leite Funchal , Ferraz Victor Hugo Gomes , Silva Juliana de Oliveira Nunes da , Barroso Suellen de Almeida , Souza Vitória Meireles Felipe de
Published: February 2022

Este artigo apresenta como objetivo analisar as questões bioéticas na área da saúde frente a Covid-19. É uma proposta de reflexão, com abordagem qualitativa do tipo descritiva sobre a análise bioética frente a Covid-19 num diálogo baseado nos princípios que a contextualizam que são: a beneficência, a autonomia e a justiça. Este artigo está pautado nas seguintes discussões: as questões bioéticas sobre a violência contra o idoso na Pandemia da Covid-19; a autonomia do cliente oncológico na ótica da bioética durante a Pandemia da Covid-19 e a análise bioética na Pandemia da Covid-19. Os desafios da bioética em relação as questões relacionadas ao direito a autonomia e o acesso aos serviços de saúde enunciam problemas de saúde pública no panorama brasileiro mas, destacam um alerta necessário para repensar as práticas de cuidado a população através das políticas públicas. Para ampliar as discussões recomenda-se pesquisas sobre a Covid-19 com um enfoque bioético sem a pretensão de esgotar mas, ampliar as discussões, evidenciando outras temáticas relevantes sobre a Covid-19 no que diz respeito a dignidade humana.
Ethnopharmacological studies in 21st century Brazil: a systematic review
Authors: Silva Alex Sander Lopes da , Carvalho Maria Luiza Silveira de , Benevides Clicia Maria de Jesus
Published: February 2022

Brazil is a country with a large party of the population, including traditional communities, that use plants for medicinal purposes, however, the prospect of drugs derived from plants is still little explored. The present study aimed to carry out a systematic review of the literature, in an attempt to understand how studies involving ethnopharmacology have developed in Brazil during the 21st century. The Scielo and PubMed data bases were used, using the keywords “ethnopharmacology” and “Brazil”. In a total of 212 articles were selected and the highest number of publications in the years of, respectively: 2018 (9.43%), 2020 (8.96%) and 2014 (8.96%). Experimental studies (laboratory studies, such as phytochemicals and biological activity) accounted 41.98% of the total, followed by literature reviews (36.32%) and ethno-directed interviews (20.28%). The results showed that the most common types of studies were popular use and biological activity (33.96%), followed by studies of popular use, phytochemical composition and biological activity (21.70%) and ethno-directed survey (20.75%). The most cited botanical families were Fabaceae (8.49%), Asteraceae (5.19%) and Lamiaceae (2.83%) and the main biological activities evaluated were anti-inflammatory (10.85%), antimicrobial (10 .85%), antimalarial (5.19%) and antioxidant (4.72%). Among the traditional communities surveyed were rural communities (50%) and quilombola communities (13.64%). The present study indicates that there was a significant increase in publications involving ethnopharmacology in Brazil, mainly from 2010, associated with a greater diversification of the researched objectives.
Analgesic effect of photobiomodulation after placement of elastomeric separators: randomized controlled clinical trial
Authors: Ortega Silvana Machado , Gonçalves Marcela Leticia Leal , Schalch Tânia Oppido , Silva Tamiris , Gallo Juliana Maria Altavista Sagretti , Altavista Olga Maria , Deana Alessandro Melo , Motta Lara Jansiski , Fernandes Kristianne Porta Santos , Mesquita-Ferrari Raquel Agnelli , Brugnera Júnior Aldo , Horliana Anna Carolina Ratto Tempestini , Bussadori Sandra Kalil
Published: February 2022

Objective: Pain resulting from the positioning of elastomeric separators is a strong reason for abandoning orthodontic treatment. So, this study aims to verify the analgesic effects of photobiomodulation (PBM) in participants submitted to orthodontics with elastomeric separators. Methods: Participants were individuals who received separators on the mesial and distal surfaces of the first molars. They were randomly separated into two groups: an experimental group that received photobiomodulation (PBM) (n=22) and a placebo group (n=22). After the positioning of the separators, the PBM group received one application of PBM (2 J of energy applied in 20 seconds per point, adding up to 12 J per molar (6 J on the vestibular surface and 6 J on the lingual surface) over the cervical portion and the apical third of the tooth. Pain was measured one hour after placement, with the aid of a visual analog scale (VAS). Statistical analysis involved the Mann-Whitney, Fisher’s Exact and chi-square tests. Results: Reports of severe pain only occurred in the placebo group. However, a larger percentage of the individuals in the PBM group reported feeling moderate pain compared to this same intensity in the placebo group. No significant differences among groups were found with regards to reports of mild pain and no pain. An association was found between pain and the female sex in both groups. Conclusion: Significant difference was found in severe pain sensitivity when PBM was applied after the positioning of elastomeric separators, favoring the irradiated participants. Thus, PBM may be a useful tool in orthodontic treatment. Clinical Trials Reference Number (www.ClinicalTrials.gov), NCT03939988.
Promoção da saúde mental: o atendimento de adolescentes com sintomas depressivos em uma clínica-escola
Authors: Silva Daniela Souza da , Schröder Nádia Teresinha , Gedrat Dóris Cristina
Published: February 2022

Os adolescentes formam um grupo vulnerável quanto ao desenvolvimento de alguns transtornos psicológicos, dentre eles a depressão, cuja importância dos atendimentos em saúde mental desse público é reconhecida. Este estudo teve como objetivo identificar a percepção dos adolescentes com sintomas depressivos quanto aos benefícios do atendimento recebido em uma clínica-escola que oferece serviços psicológicos na cidade de Manaus-AM. É uma pesquisa com abordagem qualitativa na qual participaram 10 adolescentes na faixa etária de 15 a 18 anos de idade atendidos em 2020 e 2021. Os dados coletados nas entrevistas semiestruturadas foram analisados de acordo com a análise de conteúdo temática. Os benefícios identificados foram: aumento da autoestima; benefícios no relacionamento familiar; benefícios durante a pandemia de COVID 19; diminuição/ausência da autolesão e de outros sintomas. Esses benefícios podem não significar uma remissão total dos sintomas depressivos, porém houve mudanças positivas na qualidade de vida dos adolescentes.
Mortalidade e alterações de parâmetros laboratoriais na presença de culturas positivas para bactérias e fungos em pacientes críticos com COVID-19 em hospital terciário de ensino de Mato Grosso do Sul, Brasil
Authors: Stringhetta Giulia Rodrigues , Saad Bruna Abdul Ahad , Almeida Eliane Borges de
Published: February 2022

O objetivo do presente estudo foi avaliar a mortalidade e as alterações de parâmetros laboratoriais na presença de culturas positivas para bactérias e fungos em pacientes COVID-19 positivos admitidos nos CTIs, em um hospital terciário de ensino de Mato Grosso do Sul. Trata-se de um estudo observacional retrospectivo realizado por meio de coleta de dados clínicos e laboratoriais de pacientes adultos admitidos nos CTIs, com diagnóstico confirmado para SARS-CoV-2, entre os meses de julho e agosto de 2020. A presença de ao menos uma cultura positiva em pacientes críticos com COVID-19 foi associada a maiores taxas de mortalidade, maiores períodos de internação, e a maiores níveis de D-dímero e PCR. Pacientes do sexo masculino foram mais propensos a culturas positivas, e idades mais avançadas foram associadas a contagens plaquetárias mais baixas. Contagens de leucócitos mais elevadas e contagens plaquetárias mais baixas foram também associadas a maiores taxas de mortalidade. As culturas que apresentaram maior taxa de positividade foram as culturas de aspirado traqueal. Os principais microrganismos encontrados nos exames de cultura foram a levedura Candida albicans e as espécies de Staphylococcus coagulase negativas. As bactérias Acinetobacter baumannii e Klebsiella pneumoniae destacaram-se por apresentarem perfis de resistência mais frequentes. Nota-se, portanto, a importância da adoção de medidas que previnam infecções hospitalares secundárias em pacientes com COVID-19 e o desenvolvimento de mecanismos de resistência por microrganismos de relevância clínica. O laboratório destaca-se na identificação desses microrganismos e no direcionamento para o uso de antibióticos e antifúngicos mais apropriados para cada caso específico.
Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS: Revisão integrativa
Authors: Salgueiro Francisco Haeverson Dias , Santos Teresa Maria Momensohn
Published: February 2022

Introdução: Existe a discussão se o HIV/AIDS ou o tratamento antirretroviral é responsável por manifestações clínicas generalizadas envolvendo o sistema auditivo e/ou o sistema vestibular. Objetivo: Realizar revisão integrativa sobre a Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS. Método: Utilizando-se do critério PICOS, para responder à seguinte questão: O HIV/AIDS são responsáveis por manifestações clínicas generalizadas envolvendo o sistema vestibular? A coleta dos dados a partir das bases: Embase/Elsevier; Lilacs; PubMed; Scopus e Web Of Science, no período de 2010 a 2021. Foram incluídos: artigos completos publicados português, inglês e espanhol, estudo caso-controle, estudo de coorte, estudo piloto, com desenho longitudinal e transversal, que relatam alterações otoneurológicas em pessoas vivendo com HIV/AIDS que foram submetidos a exames de vertigem e/ou tontura. Os descritores basearam-se no Decs - Descritores em Ciências da Saúde - e Mesh Terms, na língua inglesa. Foram excluídos os trabalhos: resumos, anais de congressos, relato de casos, estudos que tenham população com idade inferior a 10 anos e superior a 50 anos, artigos sobre HIV associados a outras patologias de base, Artigos de revisão. Resultados: A pesquisa resultou em 735 estudos identificados nas bases de dados e após a aplicação dos critérios de inclusão restaram 14 artigos para a análise descritiva. Conclusão: Após a conclusão desta revisão de literatura foi possível observar que não há consenso na literatura sobre os efeitos do uso da terapia antirretroviral sobre o sistema vestibular de pessoas vivendo com HIV (PVHIV) ou com a síndrome da imunodeficiência (AIDS).
Hábitos sexuais de mulheres com câncer ginecológico
Authors: Modesto Felipe Cardozo , Lattanzi Letícia Viana Chebabe Mendes , Damasceno Caroline Graça Mota , Karl Marcela Arruda , Carvalho Raquel Boechat de Moura , Ferreira Kamila Rodrigues , Lopes-Souza Patrícia , Pimentel Natalia Beatriz Lima , Oliveira Adriana Maria de , Andrade Karla Biancha Silva de
Published: February 2022

Introdução: A progressão da doença e os efeitos colaterais dos tratamentos repercutem na vida das pacientes com câncer ginecológico. Ponderar sobre hábitos sexuais após diagnóstico pode facilitar entender fatores psicológicos e físicos que influenciam na sexualidade. Objetivos: Verificar os hábitos sexuais de mulheres com câncer ginecológico após diagnóstico e os fatores que impactam na sexualidade dessas mulheres. Métodos: Pacientes hospitalizadas >18 anos, com câncer ginecológico, responderam questionário com 16 questões fechadas, 11 sobre perfil clínico e 5 sobre hábitos sexuais pós diagnóstico. Resultados: Participaram do estudo, 83 mulheres, 55,7±13,5 anos. 34,8% com estadiamento >IIb. 77,11% declaram não ter vida sexual ativa, estando 36,7% atribuído à ausência de parceiro, 12,05% por dor, 16,87% por perda da libido e 13,25% por medo ou limitação clínica. 26,51% das mulheres referem impacto da sexualidade na sua qualidade de vida. Conclusão: A situação conjugal influencia na função sexual das mulheres, mas dor e perda de libido são fatores que mais impactam na sexualidade dessas mulheres. Maior exploração dessa temática faz-se necessário para melhor instruções das pacientes, acompanhantes e, sobretudo, dos profissionais de saúde, para elaboração de estratégias com foco na qualidade de vida.
Proposta de Linha de Cuidado para a Meningococcemia: Detalhando o modelo
Authors: Schramm Neto Fernando Antônio Ramos , Faria Carolina Dourado de , Gordiano Filho Alberto Araújo , Barbosa Anna Luyse Cerqueira , Blumetti Camila Rodrigues , Fidalgo Hellen Moraes Caldas Coqueijo , Barros Isadora Rodrigues da Costa , Oliveira Lahyse de Oliveira e , Lima Luana Beatriz Santos Barbosa , Gonçalves Maria Clara Bezerra , Andrade Pedro Alves de , Blanc Sara Otoni , Alcântara Yasmin de Fátima Vilasboas , Braga Alecianne Azevedo
Published: February 2022

A doença meningocócica constitui-se como uma infecção causada pela bactéria Neisseria meningitidis, e se caracteriza por gerar, dentre outras sintomatologias, mal-estar, calafrios e cefaleia. Dados dos últimos anos evidenciam uma queda relativa do número de acometimentos por esta enfermidade no Brasil, contudo, ainda permanece sendo um grave problema de saúde pública para o país. Portanto, o objetivo deste estudo foi propor a criação de uma nova Linha de Cuidado para a meningococcemia, detalhando todo o modelo apresentado, de forma a englobar os principais níveis de atenção à saúde: primária, secundária e terciária. Para isso, foi feita uma revisão, visando analisar as principais características da doença, bem como apresentar seus dados epidemiológicos, associado a um detalhamento dos pontos principais da Linha de Cuidado proposta. Dentre os resultados apresentados, observa-se um novo método de integrar as redes de atenção à meningococcemia, de forma a garantir um atendimento mais efetivo aos pacientes portadores de tal enfermidade, com a proposta da nova Linha de Cuidado. Por fim, conclui-se que a meningococcemia se trata de uma doença ainda presente de forma significativa em território brasileiro. Portanto, a proposta da Linha de Cuidado possui importância significativa, visto que cumpre função de complementar as medidas terapêuticas já existentes.
Comprehensive medication management of kidney transplanted patients
Authors: Reis Patrícia Mara dos , Oliveira Isabela Diniz de , Coelho Pollyanne Lacerda , Dias Sílvia Novaes , Silva Luana Kellen de Oliveira , Chemello Clarice
Published: February 2022

Kidney transplant patients use several medications, which increases the risk of developing drug-related problems. This is a pre-post-intervention study, carried out in a transplant outpatient clinic in Belo Horizonte, Minas Gerais, Brazil, with post-transplant patients using tacrolimus. Pharmacy consultations were carried out in individual offices, and the initial and final status were measured between the first and the last consultation. Satisfaction with the pharmaceutical service was also assessed. Thirty-nine drug-related problems were identified, 64.3% of patients presenting at least one, of which 79.5% were resolved (p<0.001). The most frequent were “use of unnecessary medications” (26.5%), with omeprazole being the most prescribed medication for this situation. Polymedicated patients had more drug-related problems (p = 0.001). 49 interventions were performed, 51.02% were accepted. The most accepted interventions were recommendations for guidelines regarding the time of administration and reduction of adverse drug reactions (100%) and suspension of treatment (92.3%). In the end, the proportion of patients with stable clinical status increased from 35 .7% to 83.3% (p<0.001). Patients related the pharmaceutical service as very good, reporting the desire for its continuity.  Comprehensive medication management positively impacted the patient's clinical situation, proved to be effective in solving drug-related problems, and was very well evaluated by the patients. It is recommended that polymedication is a priority criterion for this service.
PEMANFAATAN ASAP CAIR DARI LIMBAH PADAT KELAPA SAWIT PERKEBUNAN KELAPA SAWIT DI LAHAN BASAH SEBAGAI INSEKTISIDA ALAMI
Authors: Soedijo Samharinto , Pramudi Muhammad Indar , Rosa Helda Orbani , Maulana Ikhsan , Rima Priska Deyana , Putra Gusti Muhammad Ahsin Anggarda
Published: February 2022

Telah dilakukan penelitian penggunaan asap cair dari limbah padat kelapa sawit berupa tandan kosong serabut dan cangkang. Tujuan penelitian adalah untuk mempelajari pengaruh asap cair terhadap larva Spodoptera litura di laboratrium dan kemampuan asap cair untuk mengendalikan hama daun tanaman sawi, kedelai, dan hama polong kedelai. Penelitian dilakukan di laboratorium dan di lapangan, di laboratorium dengan menggunakan serangga uji S. litura yang diberi pakan yang dicelupkan (sandwich daun) ke dalam asap cair dan dengan menyemperotkan asap cair langsung ke larva S. litura, sedangkan penelitian lapangan dilakukan   dengan penyemprotan asap cair pada dua jenis tanaman sayuran, yaitu sawi dan kedelai .  Hasil penelitian di laboratorium menunjukkan bahwa  perlakuan asap cair metode semprot lebih mampu mematikan larva S. litura dibandingkan dengan metode sandwich daun, sedangkan  metode sandwich daun lebih mampu menghambat pembentukan imago. Penelitian lapangan secara statistik antara perlakuan asap cair tidak menunjukkan perbedaan nyata  terhadap intensitas kerusakan daun baik pada tanaman sawi maupun  kedelai, perbedaan nyata hanya pada berat segar tanaman sawi.
Uji Daya Hambat Fungisida Nabati terhadap Colletotrichum sp. dan Sclerotium sp. Secara In-Vitro
Authors: Afrianti Neli , Taufik Muhammad , Gusnawaty HS Gusnawaty HS , Khaeruni Andi , Asniah Asniah
Published: February 2022

Buah tomat memiliki kandungan vitamin C, ß-carotene, lycopene yang penting bagi kesehatan. Selain itu nilai ekonomi tomat juga cukup tinggi sehingga menarik banyak petani untuk membudidayakannya. Saat ini petani tomat menghadapi kendala yaitu serangan penyakit bercak daun yang dapat disebabkan oleh beberapa patogen seperti Alternaria sp., Colletotrichum sp., Sclerotium sp., dan Pestaliopsis sp.Kompleks patogen tersebut menyulitkan petani tomat untuk mengendalikannya. Alternatif yang ditawarkan adalah penggunaan pestisida nabati berbahan minyak cengkeh dan ekstrak kulit jambu mete-phymar. Tujuan penelitian adalah mengevaluasi kemampuan fungisida nabati untuk mengendalikan patogen penyebab bercak daun tomat. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan tujuh perlakuan yaitu kontrol (N0), pestisida sintetik 2 mL (N1) phymar 10 mL (N2), phymar 20 mL (N3), phymar 30 mL (N4), minyak cengkeh 2,5 mL (N5), minyak cengkeh 5 mL (N6) dan minyak cengkeh 7 mL (N7), setiap perlakuan diulang empat kali. Hasil penelitian menunjukkan bahwa perlakuan fungisida nabati phymar dan minyak cengkeh mampu menghambat pertumbuhan cendawan patogen Colletotrichum sp dan Sclerotium sp. Fungisida nabati minyak cengkeh dengan konsentrasi 2,5 ml/L media agar sudah efektif menghambat perkembangan Colletotrichum sp dan Sclerotium sp. secara in-vitro dengan daya hambat masing-masing sebesar 100%.Kata kunci : bercak daun, Colletotrichum., fungisida, Sclerotiu
PENGARUH PENGGUNAAN SISTEM TEKNOLOGI INFORMASI TERHADAP KUALITAS LAPORAN KEUANGAN PADA BALAI LATIHAN KERJA KENDARI
Authors: Nurddin Emilia , Maya Sari Ika , Mardiana Anna
Published: February 2022

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh penggunaan Sistem Teknologi Informasi terhadap kualitas laporan keuangan pada Balai latihan Kerja Kendari. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kausalitas dengan pendekatan kuantitatif. Teknik sampel yang digunakan dalam penelitian ini adalah sensus sampling, dimana sampel dalam penelitian ini merupakan Tim Penyusun Laporan Keuangan Anggaran Pendapatan dan Belanja Negara (APBN) pada Satuan Kerja Balai Latihan Kerja Kendari sebanyak 40 orang. Instrumen penelitian menggunakan kuesioner, sedangkan alat analisis yang digunakan adalah analisis regresi linear sederhana menggunakan skala interval.Hasil penelitian ini menunjukkan bahwa Sistem Teknologi Informasi berpengaruh signifikan terhadap Kualitas Laporan Keuangan pada Balai Latihan Kerja (BLK) Kendari. Balai Latihan Kerja (BLK) Kendari telah mampu dalam menerapkan serta memanfaatkan fungsi dari sistem teknologi informasi berupa Sistem Aplikasi Satker (SAS) dalam segala mekanisme pengelolaan laporan keuangan secara tepat dan maksimal, sehingga pemanfaatan sistem teknologi informasi ini akan berdampak pada kemudahan dalam melaksanakan tugas utamanya berkaitan dengan pengolahan laporan keuangan secara lebih tepat, cepat, dan berkualitas dalam rangka memenuhi segala pertanggungjawaban keuangan yang terjadi selama Balai Latihan Kerja (BLK) Kendari memenuhi tujuan serta visi dan misi organisasinya.
PENGARUH SISTEM PENGENDALIAN MANAJEMENTERHADAP KINERJA KARYAWAN STUDI PADA PT. DACHTRACO RAYA
Authors: Nasrullah Dali Nasrullah , Nurnaluri Sitti , Hasniati H Hasniati H
Published: February 2022

Penelitian ini bertujuan untuk mengetahui pengaruh sistem pengendalian manajemen terhadap kinerja karyawan PT. Dachtraco Raya. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan sumber data primer yang diperoleh secara langsung oleh responden. Sampel dalam penelitian ini terdiri dari 20 karyawan dengan pengambilan sampel menggunakan sampling jenuh (sensus), yaitu teknik penentuan sampel bila semua anggota populasi digunakan sebagai sampel. Hasil analisis regresi menunjukkan bahwa sistem pengendalian manajemen berpengaruh positif signifikan terhadap kinerja karyawan. Hasil penelitian ini dapat dijadikan sebagai bahan masukkan bagi PT. Dachtraco Raya dalam rangka peningkatan kualitas kerja karyawan untuk mencapai tujuan yang ingin dicapai oleh perusahaan.
ANALISIS KONTRIBUSI PAJAK HOTEL DAN PAJAK RESTORAN UNTUK MENINGKATKAN PENDAPATAN ASLI DAERAH (PAD) DI KABUPATEN KOLAKA
Authors: Maya Sari Ika , Intihanah Intihanah , Marnianti Putri Septi
Published: February 2022

Penelitian ini bertujuan untuk mengetahui dan menjelaskan besarnya kontribusi dan efektivitas Pajak Hotel Melati dan Pajak Restoran Untuk Meningkatkan Pendapatan Asli Daerah di Kabupaten Kolaka. Manfaat dari penelitian yaitu agar memberikan informasi tentang beesarnya kontribusi dan tingkat efektvitas Pajak Hotel Melati dan Pajak Restoran Untuk Meningkatkan Pendapatan Asli Daerah di Kabupaten Kolaka. Penelitian ini menggunakan metode analisis deskriptif. Teknik pengumpulan data yaitu wawancara dan dokumentasi berupa data target dan realisasi kontribusi dan tingkat efektivitas Pajak Hotel Melati dan Pajak restoran.Hasil Penelitian menunjukkan bahwa kontribusi Pajak Hotel Melati dan Pajak Restoran untuk meningkatkan Pendapatan Asli Daerah di Kabupaten Kolaka yaitu sangat kurang dengan persentase masih dibawah 10%. Demikian juga efektivitas Pajak Hotel Melati pada tahun 2017 dan 2018 dibawah 100% tergolong kriteria belum efektif tetapi pada tahun 2019 meningkat diatas 100% sehingga tergolong kriteria sangat efektif. Berbanding terbalik dengan efektivitas Pajak Restoran pada tahun 2017 sebesar 84,98% tergolong kriteria cukup efektif dan ditahun 2018 sebesar 93,37 tergolong kriteria efektif, kemudian terjadi peningkatan di tahun 2019 sebesar 118,02% tergolong kriteria sangat efektif.
PERHITUNGAN PPH BADAN PADA CV. SINAR TIMU
Authors: Yusuf Satira , Akib Mulyati , Enil Syahban Wa Ode
Published: February 2022

Penelitian ini bertujuan untuk mengetahui bagaimana perhitungan PPh Badan Pada CV. Sinar Timu. Jenis data yang digunakan dalam penelitian ini adalah data kualitatif. Metode pengumpulan data yang digunakan adalah metode wawancara dan dokumentasi. Metode analisis data yang digunakan adalah metode analisis deskriptif Kualitatif.Hasil penelitian menunjukan bahwa perhitungan Pajak Penghasilan Badan (PPh) CV. Sinar Timu sudah melakukan perhitungan kewajiban perpajakan menurut Undang-undang No. 36 tahun 2008 pasal 4 ayat (2) dengan benar karena dalam perhitungannya menggunakan tarif final jasa konstruksi sebagai penyedia jasa sebesar 3% dan sesuai dengan Peraturan Pemerintah Nomor 40 Tahun 2009 tentang Pajak Penghasilan Atas Penghasilan Dari Usaha Jasa Konstruksi. Dengan adanya tarif final jasa konstruksi membuat perusahaan dalam menyetorkan dan melaporkan kewajiban perpajakan akan menjadi lebih ringan karena telah di berikan pemahaman oleh kantor pajak seperti apa mekanisme yang di lakukan pada saat penyetoran dan pelaporan kewajiban perpajakan.
ANALISIS KREDIT USAHA RAKYAT (KUR) BAGI PENGEMBANGAN UMKM DI KOTA KENDARI (Studi Kasus Pada Bank Sultra)
Authors: Abdullah Muntu , Tamburaka Sulvariany , Isda Isda
Published: February 2022

Penelitian ini bertujuan untuk menganalisis Bagaimana Perkembangan Usaha Mikro,Kecil, Menengah (UMKM) dalam pengembangan sektor usaha sebelum dan sesudah adanyapenggunaan dana Kredit Usaha Rakyat (KUR). Metode analisis yang digunakan dalampenelitian ini adalah metode analisis deskriptif kualitatif. Sumber data yang digunakan dataprimer dan data sekunder. Metode pengumpulan data yang digunakan dalam penelitian iniadalah wawancara dan dokumentasi. Hasil dari penelitian ini menunjukan bahwa setelahadanya dana Kredit Usaha Rakyat (KUR) yang diluncurkan pemerintah melalui Bank Sultrasangat berdampak positif dalam membantu pelaku UMKM dalam mengembangkan usahanya,baik dari segi permodalan, omset penjualan, dan dari segi keuntungan yang sangatberpengaruh dalam menumbuh kembangkan usaha UMKM. Perkembangan kinerja UMKMsetelah adanya dana Kredit Usaha Rakyat (KUR) mengalami peningkatan di bandingkansebelum adanya dana KUR di tahun-tahun sebelumnya, hal ini dapat dilihat dengan adanyaperbedaan sebelum dan sesudah adanya dana Kredit Usaha Rakyat (KUR).
PENGARUH KEJELASAN SASARAN ANGGARAN DAN SISTEM PELAPORAN TERHADAP AKUNTABILITAS KINERJA PEMERINTAH DAERAH KABUPATEN KONAWE
Authors: Maya Sari Ika , Intihanah Intihanah , Aris Aras Musa Muh. Alfayet
Published: February 2022

Tujuan dari penelitian ini adalah untuk mendapatkan bukti empiris tentangpengaruh secara parsial dan simultan kejelasan sasaran anggaran dan sistempelaporan terhadap akuntabilitas kinerja pemerintah Pemerintah Daerah Konawe.Sampel penelitian ini adalah seluruh kepala departemen / instansi dan Kepala Seksi /Sub Bagian Keuangan pada 29 SKPD Konawe Pengumpulan data dilakukan denganmenyebarkan kuisioner kepada 58 kepala departemen / instansi dan kepala bagian /sub bagian keuangan. Pengolahan data dilakukan dengan menggunakan analisisregresi berganda. Hasil penelitian menunjukkan bahwa kejelasan sasaran anggarandan sistem pelaporan berpengaruh signifikan atas akuntabilitas kinerja instansipemerintah.
PENGUKURAN KINERJA KEUANGAN MENGGUNAKAN METODE ECONOMIC VALUE ADDED (EVA) PADA BANK SULTRA
Authors: Tamburaka Sulvariany , Basru Wawo Andi , Sarni Siti
Published: February 2022

Penelitian ini bertujuan untuk mengetahui dan mengukur kinerja keuanganmenggunakan metode Economic Value Added (EVA) pada Bank Sultra periode tahun2016-2019, yang berguna untuk mengetahui besarnya nilai tambah ekonomiperusahaan. Adapun alat yang digunakan dalam penelitian ini adalah analisis deskriptifkuantitatif dan menggunakan data skunder sebagai sumber data. Hasil penelitian inimenunjukan bahwa kinerja keuangan Bank Sultra periode tahun 2016-2019 diukurmenggunakan metode Economic Value Added (EVA) memiliki kinerja yang baik. Halini sesuai dengan hasil pengukuran nilai EVA yang bernilai positif atau lebih besar darinol sehingga terjadi nilai tambah ekonomis bagi Bank Sultra karena laba yangdihasilkan dapat memenuhi harapan pada penyandang dana.
PENGARUH AKUNTABILITAS DAN PENGETAHUAN AUDIT TERHADAP KUALITAS HASIL KERJA AUDITOR INTERNAL (Studi Pada Kantor Inspektorat Provinsi Sulawesi Tenggara)
Authors: Hadisantoso Erwin , Dali Nasrullah , Kurnia Ulva
Published: February 2022

Penelitian ini bertujuan untuk menguji dan mengetahui pengaruh akuntabilitas danpengetahuan audit terhadap kualitas hasil kerja auditor internal. Variabel pada penelitian initerdiri dari akuntabilitas dan pengetahuan audit sebagai variabel independen, dan kualitasaudit sebagai variabel dependen. Metode pengumpulan data menggunakan kuesioner.Sampel pada penelitian ini adalah 38 auditor pada Inspektorat Provinsi Sulawesi Tenggara.Analisis data menggunakan metode analisis deskriptif dan analisis linear berganda denganbantuan aplikasi software IBM SPSS Statistics Versi 26. Hasil penelitin ini menunjukkanbahwa (1) akuntabilitas secara parsial berpengaruh positif signifikan terhadap kualitas hasilkerja auditor internal. (2) Pengetahuan audit secara parsial berpengaruh positif signifikanterhadap kualitas hasil kerja audit. (3) akuntabilitas dan pengetahuan audit secara simultanberpengaruh positif signifikan terhadap kualitas hasil kerja auditor internal. Kesimpulanpenelitian ini yaitu semakin tinggi akuntabilitas dan pengetahuan audit maka kualitas hasilkerja auditor internal akan semakin meningkat.
ANALISIS PENERAPAN SISTEM AKUNTANSI KEUANGAN DAERAH PADA BADAN PENGELOLAAN KEUANGAN ASET & PENDAPATAN DAERAH KABUPATEN MUNA BARAT
Authors: Anto La Ode , Awaluddin Ishak , Suwarno Try Edi
Published: February 2022

Penelitian ini bertujuan untuk mengetahui kesesuaian penerapan SistemAkuntansi Keuangan Daerah pada Badan Pengelolaan Keuangan Aset dan PendapatanDaerah Kabupaten Muna Barat terhadap Standar Akuntansi Pemerintahan dan PedomanPengelolaan Keuangan Daerah. Teknik analisis data yang digunakan dalam penelitianini adalah analisis deskriptif kualitatif. Pengumpulan data penelitian menggunakanteknik wawancara (interview) dan dokumentasi.Hasil penelitian ini menunjukan bahwa Badan Pengelolaan Keuangan Aset danPendapatan Daerah menggunakan Aplikasi SIMDA Keuangan dan Microsoft Excelyang membantu pengelolaan data keuangan pemerintah daerah. Penerapan SIMDAKeuangan sebagai Sistem Akuntansi Keuangan Daerah di Badan PengelolaanKeuangan Aset dan Pendapatan Daerah Kabupaten Muna Barat saat ini belum begituefektif. Hal tersebut terkait dengan masalah infrastruktur berupa jaringan dan fasilitasyang memadai dan masalah kesiapan Sumber Daya Manusia. Penyusunan LaporanKeuangan SKPD BPKAPD yang terdiri dari : 1) Laporan Realisasi Anggaran, 2)Laporan Operasional 3) Neraca, 4) Laporan Perubahan Ekuitas 5) Catatan Atas LaporanKeuangan.
PENGARUH E-COMMERCE TERHADAP SISTEM INFORMASI AKUNTANSI DAN KEPUTUSAN BERWIRAUSAHA (Studi Kasus Mahasiswa Jurusan Akuntansi FEB)
Authors: Dharmawati Tuti , Mirosea Nitri , Nirmaya Nirmaya
Published: February 2022

Penelitian ini bertujuan untuk menguji dan menjelaskan pengaruh e-commerceterhadap sistem informasi akuntansi dan keputusan berwirausaha. Populasi dalampenelitian ini adalah mahasiswa jurusan akuntansi FEB, Universitas Halu Oleo dansampel dalam penelitian ini yaitu mahasiswa aktif yang menggunakan e-commerce.Metode pengumpulan data menggunakan kuesioner. Analisis data menggunakan metodeanalisis deskriptif dan analisis jalur. Hasil penelitian ini menunjukkan bahwa (1) ecommercesecara parsial dan secara langsung berpengaruh signifikan terhadap sisteminformasi akuntansi. (2) e-commerce secara parsial dan secara langsung berpengaruhsignifikan terhadap keputusan berwirausaha. (3) sistem informasi akuntansi secaraparsial dan secara langsung berpengaruh signifikan terhadap keputusan berwirausaha.Pada uji koefisien determinasi nilai R Square total (R2m ) sebesar 0,99, hal inimenunjukkan bahwa kemampuan variabel independen mampu menjelaskan variabelendogennya dengan nilai koefisien determinasi total sebesar 99%, sedangkan sisanyasebesar 1% dijelaskan oleh variabel lain yang tidak diteliti pada penelitian ini.
School Building Energy Assessment Using Lean Energy Management Strategies
Authors: Ahamad Abdul Hadi , Abidin Nur IzieAdiana , Zakaria Rozana , Aminudin Eeydzah , Khan Jam Shahzaib , Sahamir Shaza Rina , Azman Shamila , Redzuan Amir Alhamdi , Lau Santi Edra Nisa , Mohd Yusoff Mohamad Faiz
Published: February 2022

In Malaysia, there are approximately 10,220 active schools, and these schools’ electricity bills are under the responsibility of the Malaysian Ministry of Education. The demand for energy use is expected to rise dramatically in the coming years due to many factors such as the increasing number of student enrolments and the demand for a comfortable indoor environment in response to global climate effects. Therefore, there are many ideas, concepts, and technologies that have been introduced towards energy conservation in buildings. This study aims to identify key implementation of energy conservation measures and audit energy consumption of five secondary schools. Case studies derived were from schools that participated in Energy Efficiency Challenge hosted by the Energy Commission. It was found that the schools’ usage of electricity exceeded their need. Based on the implementation of energy management conservation measures throughout 2016 to 2019, there were gradual reductions and downtrends in energy consumption graphs.
Distribution Map of Peristaltic Waves in the Chicken Embryonic Gut Reveals Importance of Enteric Nervous System and Inter-Region Cross Talks Along the Gut Axis
Authors: Shikaya Yuuki , Takase Yuta , Tadokoro Ryosuke , Nakamura Ryo , Inaba Masafumi , Takahashi Yoshiko
Published: February 2022

Gut peristaltic movements recognized as the wave-like propagation of a local contraction are crucial for effective transportation and digestion/absorption of ingested materials. Although the physiology of gut peristalsis has been well studied in adults, it remains largely unexplored how the cellular functions underlying these coordinated tissue movements are established along the rostral-caudal gut axis during development. The chicken embryonic gut serves as an excellent experimental model for elucidating the endogenous potential and regulation of these cells since peristalsis occurs even though no ingested material is present in the moving gut. By combining video-recordings and kymography, we provide a spatial map of peristaltic movements along the entire gut posterior to the duodenum: midgut (jejunum and ileum), hindgut, caecum, and cloaca. Since the majority of waves propagate bidirectionally at least until embryonic day 12 (E12), the sites of origin of peristaltic waves (OPWs) can unambiguously be detected in the kymograph. The spatial distribution map of OPWs has revealed that OPWs become progressively confined to specific regions/zones along the gut axis during development by E12. Ablating the enteric nervous system (ENS) or blocking its activity by tetrodotoxin perturb the distribution patterns of OPWs along the gut tract. These manipulations have also resulted in a failure of transportation of inter-luminally injected ink. Finally, we have discovered a functional coupling of the endpoint of hindgut with the cloaca. When surgically separated, the cloaca ceases its acute contractions that would normally occur concomitantly with the peristaltic rhythm of the hindgut. Our findings shed light on the intrinsic regulations of gut peristalsis, including unprecedented ENS contribution and inter-region cross talk along the gut axis.
Gradients of PI(4,5)P2 and PI(3,5)P2 Jointly Participate in Shaping the Back State of Dictyostelium Cells
Authors: Li Dong , Sun Feifei , Yang Yihong , Tu Hui , Cai Huaqing
Published: February 2022

Polarity, which refers to the molecular or structural asymmetry in cells, is essential for diverse cellular functions. Dictyostelium has proven to be a valuable system for dissecting the molecular mechanisms of cell polarity. Previous studies in Dictyostelium have revealed a range of signaling and cytoskeletal proteins that function at the leading edge to promote pseudopod extension and migration. In contrast, how proteins are localized to the trailing edge is not well understood. By screening for asymmetrically localized proteins, we identified a novel trailing-edge protein we named Teep1. We show that a charged surface formed by two pleckstrin homology (PH) domains in Teep1 is necessary and sufficient for targeting it to the rear of cells. Combining biochemical and imaging analyses, we demonstrate that Teep1 interacts preferentially with PI(4,5)P2 and PI(3,5)P2in vitro and simultaneous elimination of these lipid species in cells blocks the membrane association of Teep1. Furthermore, a leading-edge localized myotubularin phosphatase likely mediates the removal of PI(3,5)P2 from the front, as well as the formation of a back-to-front gradient of PI(3,5)P2. Together our data indicate that PI(4,5)P2 and PI(3,5)P2 on the plasma membrane jointly participate in shaping the back state of Dictyostelium cells.
Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy
Authors: Huang Mengying , Yang Zhen , Li Yingrui , Lan Huan , Cyganek Lukas , Yuecel Goekhan , Lang Siegfried , Bieback Karen , El-Battrawy Ibrahim , Zhou Xiaobo , Borggrefe Martin , Akin Ibrahim
Published: February 2022

Background

Previous studies suggested involvement of non-ß-adrenoceptors in the pathogenesis of Takotsubo cardiomyopathy (TTC). This study was designed to explore possible roles and underlying mechanisms of dopamine D1/D5 receptor coupled signaling in arrhythmogenesis of TTC.

Methods

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) were challenged by toxic concentration of epinephrine (Epi, 0.5 mM for 1 h) for mimicking the catecholamine excess in setting of TTC. Specific receptor blockers and activators were used to unveil roles of D1/D5 receptors. Patch clamp, qPCR, and FACS analyses were performed in the study.

Results

High concentration Epi and two dopamine D1/D5 receptor agonists [(±)-SKF 38393 and fenoldopam] reduced the depolarization velocity and prolonged the duration of action potentials (APs) and caused arrhythmic events in iPSC-CMs, suggesting involvement of dopamine D1/D5 receptor signaling in arrhythmogenesis associated with QT interval prolongation in the setting of TTC. (±)-SKF 38393 and fenoldopam enhanced the reactive oxygen species (ROS)-production. H2O2 (100 μM) recapitulated the effects of (±)-SKF 38393 and fenoldopam on APs and a ROS-blocker N-acetylcysteine (NAC, 1 mM) abolished the effects, suggesting that the ROS-signaling is involved in the dopamine D1/D5 receptor actions. A NADPH oxidases blocker and a PKA- or PKC-blocker suppressed the effects of the dopamine receptor agonist, implying that PKA, NADPH oxidases and PKC participated in dopamine D1/D5 receptor signaling. The abnormal APs resulted from dopamine D1/D5 receptor activation-induced dysfunctions of ion channels including the Na+ and L-type Ca2+ and IKr channels.

Conclusions

Dopamine D1/D5 receptor signaling plays important roles for arrhythmogenesis of TTC. Dopamine D1/D5 receptor signaling in cardiomyocytes might be a potential target for treating arrhythmias in patients with TTC.
Tranexamic Acid Administered During Off-Pump Coronary Artery Bypass Graft Surgeries Achieves Good Safety Effects and Hemostasis
Authors: Wang Enshi , Yuan Xin , Wang Yang , Chen Weinan , Zhou Xingtong , Hu Shengshou , Yuan Su
Published: February 2022

Background

Tranexamic acid (TXA) administered during off-pump coronary artery bypass (OPCAB) surgeries has achieved good blood control in small cohorts. We aimed to investigate the safety issues and hemostasis associated with TXA administration during OPCAB in a large retrospective cohort study.

Methods

This study included 19,687 patients with OPCAB from 2009 to 2019. A total of 1,307 patients were excluded because they were younger than 18 years or certain values were missing. Among the remaining 18,380 patients, 10,969 were in the TXA group and 7,411 patients were in the no-TXA group. There were 4,889 patients whose TXA dose was ≥50 mg/kg, and the remaining 6,080 patients had a TXA dose of <50 mg/kg. Propensity score matching (PSM) was performed between the TXA and no-TXA groups and between the high-dose and low-dose groups, and statistical analysis was performed.

Results

Tranexamic acid administration did not increase the risk of hospital death or thromboembolic events. Patients who administered TXA had less blood loss at 24 h (478.32 ± 276.41 vs. 641.28 ± 295.09, p < 0.001) and 48 h (730.59 ± 358.55 vs. 915.24 ± 390.13, p < 0.001) and total blood loss (989.00 ± 680.43 vs. 1,220.01 ± 720.68, p < 0.001) after OPCAB than the patients with non-TXA. Therefore, the risk of total blood exposure [odds ratio (OR) = 0.50, 95% CI 0.47–0.54, p < 0.001] or blood component exposure (p < 0.001) was decreased significantly in the patients who administered TXA. The TXA dosage did not impact the patient survival, thromboembolic events, or blood management.

Conclusions

The application of TXA was safe and provided blood control in patients with OPCAB, and the dosage did not affect these parameters.