bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Geometry on Artificial Tracer Dispersion in Synthetic Karst Conduit Networks
Authors: Rabah Amal , Marcoux Manuel , Labat David
Published: November 2023

This paper presents the modeling results of tracer test simulations performed using COMSOL Multiphysics (version 6.1), a powerful software for multiphysics simulation. The simulations consist of the propagation of artificial tracers injected into different model configurations. This study is based on computational fluid dynamics (CFDs), which allows us to take into consideration the turbulent regime of the water flow in conduits. The objective of this contribution is to identify the relationship between the tracer dynamics and the geometric parameters of synthetic karstic systems via a systematic investigation of the occurrence of dual-peaked breakthrough curves (BTCs) in tracer tests. Various conduit structures were proposed by modifying five key factors: conduit diameter, presence of pools, connection angle between conduits, distance of the outlet from the inlet, and number of branches. The next step will be to confront these computational experiments with real-world tracer test experiments.
Liderazgo docente universitario en los modelos del sistema gestión universitario, explorando enfoques
Authors: Palacios Pérez Ricardo , Tarifeño Ramírez Marco , Gallegos Ruiz Conejo Ada Lucia
Published: November 2023

Comprender la importancia del papel que juegan los docentes y los roles de liderazgo que desempeñan en la sociedad, es crucial, ya que la calidad de los docentes es un factor decisivo que afecta significativamente el proceso de enseñanza. Este artículo analiza los enfoques y las aproximaciones teóricas sobre el liderazgo de los profesores universitario. Se elaboró una revisión sistemática; la búsqueda se realizó Scopus, Scielo, Redalyct y Google Scholar, considerando términos como “Liderazgo Docente Universitario”, “Modelo de Gestión Universitaria”, los resultados de búsquedas según criterios de selección quedaron establecidos en 7 artículos, 5 reseñas publicadas, 2 ensayos universitarios sobre liderazgo instruccional universitario, y 1 libro sobre la experiencia universitaria exitosa en Perú. En conclusión, se reconoce que el liderazgo no se limita a la administración, sino que también se relaciona con la enseñanza, la colaboración, el servicio y la ética. Los profesores universitarios desempeñan un papel fundamental en la formación de futuros líderes y en la mejora de la calidad de la educación superior.
Perspectiva del docente en la educación inclusiva
Authors: Palomino Condo Luz Marina , Tarco Sánchez Armando , Sosa Hernández María del Pilar
Published: November 2023

La educación inclusiva es un factor que trata de maximizar la integración y cumplimiento de derechos hacia los integrantes educativos; como parte de la mediación los docentes juegan un papel fundamental tanto en sus percepciones, actitudes y prácticas pedagógicas para fortalecer la inclusión. El objetivo fue generar un análisis mediante una revisión sistemática sobre la educación inclusiva y la percepción del docente, considerando la base de datos de Scopus, Scielo, Google Schoolar y Ebsco, donde los descriotres quedaron establecido “Percepción del docente en la educación”; “Percepción del docente en la participación educativa” entre otros. Fueron seleccionado 50 artículos de los últimos 5 años; el cual tuvo como parte de los criterios de inclusión artículos académicos; en la exclusión: tipo de documento diferente (monografías, tesis, libros), descarte de duplicados. Se concluye la participación de los docentes integran en el plan del enfoque de aprendizaje, la experiencia y la práctica en el desarrollo de cambios curriculares, herramientas de observación, actividades de aprendizaje.
Competencias digitales en docentes de educación pública: Una necesidad en tiempos de COVID-19
Authors: Gómez Vinces Sandro
Published: November 2023

La pandemia por COVID-19 generó una nueva normalidad en especial a la educación; presentado dificultades con el deficiente acceso a Internet, la ausencia de planes educativos estructurados en sintonía a contenidos apropiados, y una limitante mayor docentes que no reúnen las competencias para un trabajo virtual. De acuerdo a este planteamiento, el objetivo de este estudio es analizar las competencias digitales docentes desde un aspecto reflexivo. Se realizó un artículo de reflexión, donde se seleccionó el tema relevante y personal acerca de la problemática observada de las competencias docentes en tiempo de pandemia, se realizó un proceso de investigación y recopilación información: donde se desarrolló la etapa de selección de información y recolección de artículos científicos. Se estructuró el artículo en introducción, que presentó el tema, el desarrollo exploró las reflexiones y la conclusión resume las ideas principales generadas de la reflexión. Se concluye que es ineludible el dominio de las competencias digitales para asegurar el éxito de la enseñanza virtual.
Efectividad del aprendizaje colaborativo en la educación virtual de estudiantes de educación superior
Authors: Ramírez Fernández Mirtha Jiovana
Published: November 2023

El aprendizaje colaborativo como la educación virtual presentan ventajas significativas en la educación superior, sin embargo, para maximizar sus beneficios, es fundamental abordar los desafíos relacionados con la capacitación docente, el acceso a recursos tecnológicos, la calidad, la interacción, la motivación, y la evaluación. Por ello, el objetivo de este estudio es analizar la efectividad del aprendizaje colaborativo en la educación virtual de los estudiantes de educación superior. Para lo cual se usó el diseño de revisión narrativa; para evitar sesgos la búsqueda y sistematización se dio usando bases de datos y plataformas como WoS, Scopus, Scielo, La Referencia, Redalyc, Dialnet. Los resultados de búsqueda generado según los criterios de inclusión artículos publicados durante los últimos 5 años sobre aprendizaje colaborativo, generando 35 fuentes de las cuales se seleccionaron 20 artículos. En conclusión, la efectividad del aprendizaje colaborativo en la educación virtual depende de diversos factores, incluyendo la infraestructura tecnológica disponible, la motivación y autodisciplina de los estudiantes, la capacitación y apoyo de los docentes, y la calidad de la comunicación y la coordinación en línea.
Sistem Pakar Diagnosa Keluhan Selama Masa Nifas Dengan Metode Dempster Shafer
Authors: Wijayanti Tita
Published: November 2023

Masa nifas adalah masa setelah persalinan atau dapat juga diartikan sebagai masa pulih kembali yang dimana organ-organ reproduksi akan mengalami perubahan seperti keadaan pra hamil dengan memerlukan waktu kurang lebih 6 minggu. Dewasa kini, seringkali fokus utama bagi ibu dan bayi banyak tertuju pada masa kehamilan dan persalinan, sedangkan pada masa nifas seorang ibu juga rentan terserang penyakit seperti endometritis, metritis, mastitis, abses payudara, infeksi saluran kemih, thromboplebitis, infeksi luka perineum, infeksi luka post SC, perdarahan pospartum dan baby blues yang dapat bertambah parah jika tidak ditangani dengan baik. Tujuan dari penelitian ini yaitu untuk mengimplementasikan metode Dempster Shafer pada aplikasi sistem pakar dan menguji tingkat keakuratan sistem dalam mengidentifikasi penyakit yang dapat menyerang selama masa nifas serta memberikan solusi penanganan dari hasil diagnosa. Aplikasi sistem pakar ini menghasilkan keluaran atau diagnosa berupa kemungkinan penyakit yang diderita berdasarkan keluhan atau gejala yang dialami pasien serta menampilkan besarnya nilai kepercayaan terhadap penyakit tersebut yang diperoleh dari perhitungan dengan menggunakan Dempster Shafer. Sistem ini diuji dengan menggunakan pengujian akurasi yang dimana dilakukan perbandingan antara hasil diagnosa sistem dengan hasil diagnosa pakar. Tingkat akurasi sistem dalam penelitian ini mencapai 93%, yang menunjukkan tingkat kehandalan yang tinggi dalam memberikan diagnosa yang tepat. 
Kata Kunci: Penyakit pada Masa Nifas, Sistem Pakar, Dempster Shafer
COMMUNITY EMPOWERMENT IN PROCESSING CELERY (APIUM GRAVEOLENS L) AS HAND SANITIZER IN NEIGHBOURHOOD (RW) NUMBER 05 OF BABAKAN LOA STREET, NORTH CIMAHI
Authors: Kurniati Iis , Sufa Hafizah Ilmi , Marliana Nina , Dermawan Asep
Published: November 2023

Background: The corona virus diseases 19 (COVID-19) pandemic has continued to infect the world's population in the last two years, including in Indonesia which the number of positive cases of the corona virus is already above 1.5 million people. In our country, health protocol that is effective enough to prevent transmission of the corona virus is known as 5M, including washing hands thoroughly. For maximum results, it is recommended to wash your hands for at least 20 seconds several times a day. To kill viruses and other pathogenic bacteria, it is recommended to wash hands using soap or hand sanitizer with alcohol or other antibacterial substances at least 60% concentration.

Method used is technology transfer through counseling, training and mentoring in the neighbourhood (RW) 05 Babakan Loa Street, Cimahi Utara area is processing celery to be used as a hand sanitizer.

Result: After receiving learning materials and demonstration from team, each participants who are represented by the Chair of RW 05 Babakan Loa Street, North Cimahi, received handbooks which containing guidelines for processing celery as hand sanitizer. In addition, participant also received materials and equipment needed for processing celery as hand sanitizer so that can do experience independently or in team work.

Conclusion: So that, this activity can help implement health protocols in terms of washing hands and preventing the spread of COVID-19.
Effect of CaF2 Additions on the Yield of AZ63 Magnesium Chips during Remelting
Authors: YÖRÜK Pınar , GÖKELMA Mertol
Published: November 2023

Magnesium is one of the metals listed in European Union’s critical raw materials list. Primary production of magnesium is a high energy demanding process which raised the necessity of recycling the magnesium alloys in an efficient way. Remelting those scraps under a salt flux consist of chlorides (NaCl, KCl, and MgCl2) and fluorides (CaF2) are a common process however, different alloys might behave differently when it comes to salt-metal-metal oxide interactions. Furthermore, the condition of the salt flux such as dry-mixed or pre-melted (fused) affects the coagulation and metal yield. This work presents results on the effect of CaF2 concentration and pre-melting the salt flux on metal yield during remelting of chips. A yield up to 75% was observed in the case of remelting of chips under a fused salt flux with 5.5% CaF2 concentration.
Application of Multi-Criteria Decision Making Methods for Menu Selection
Authors: İPEK Semih Latif , GÖKTÜRK Dilek
Published: November 2023

Nutritional information on menus can assist customers in making healthier eating choices. One technique being utilized to tackle the rise of overweight and obesity is the use of nutritional information on menus. Menu engineering strategies can be used to improve sales of generally healthier and higher margin items. For today's food and beverage companies, menu engineering has become essential. Companies must continually evaluate their menus in order to keep up with changing customer demands and the conditions of the competitive market. Menu engineering's core involves comparing the effectiveness of each menu. At this point, correct decision-making under numerous factors is thought to be a very challenging procedure. To evaluate alternatives according to many features, several Multi-Criteria Decision-Making (MCDM) approaches have been created. The main novelty of this paper is that four MCDM methods, including Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS), Fuzzy TOPSIS, VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR), and Fuzzy VIKOR, are employed to evaluate menu options. Comparative analysis of MCDM methods is another contribution of this study. The process of evaluating and selecting healthier menu alternatives can become challenging and time-consuming. This study pointed out how crucial it is to conduct comparative analysis using various MCDA methods and to carefully determine the right ones when addressing the issue of selecting the best menu, taking into account the values of the criterion in fuzzy numbers.
Relevancia de las competencias socioemocionales para la vida
Authors: Jolay-Benites Judith Angélica , Duran-LLaro Kony Luby , Purizaca-Gallo Ada Violeta , Mora-Aranda Rómulo Saúl
Published: November 2023

Este estudio tuvo como propósito demostrar la efectividad de la estrategia de formación con enfoque humanista para el desarrollo de las competencias socioemocionales en estudiantes de segundo grado de secundaria de la Institución Pública, Viru, 2023. Metodológicamente, el estudio se realizó bajo el enfoque cuantitativo, la investigación aplicada y el diseño cuasiexperimental. Como técnica, se empleó la experimentación y como instrumento se aplicó un test situacional JAJB-2, orientado a medir las competencias socioemocionales. La muestra estuvo constituida por 65 estudiantes, respectivamente. La data fue procesada con SPSS 26, obteniéndose un p-valor menor a 0,05 (0.000 < ,005) en el postest; es decir, los resultados señalaron una mejora significativa de las competencias socioemocionales; los cuales fueron obtenidos mediante la prueba “U” de Mann Whitney, alcanzando los niveles satisfactorio y sobresaliente. En consecuencia, se concluyó que la estrategia de formación con enfoque humanista mejoró significativamente las competencias socioemocionales de los estudiantes.
Protective Effects of Resveratrol Carbon Dots Against 6-OHDA-Induced Neurotoxicity in SH-SY5Y Cells
Authors: CİCEK Betul , DANIŞMAN Betül
Published: November 2023

Background: We aimed to investigate the ability of resveratrol carbon dots (RES C-Dots) to protect SH-SY5Y cells from oxido-inflammatory stress and apoptosis caused by 6-hydroxydopamine (6-OHDA).
Materials and Methods: In vitro PD model was generated in SH-SY5Y cells by administering of 200 µM 6-OHDA for 24 hours. Different concentrations of RES C-Dots (12.5, 25, and 50 µg/mL) were applied to the cells 30 minutes before administration of 6-OHDA.
Results: We observed that application of RES C-Dots prevented cell death induced by 6-OHDA and main-tained cell viability. As expected, RES C-Dots prevented oxidative damage induced by 6-OHDA - by strengthening the total amount of antioxidants and lowering the total amount of oxidants in SH-SY5Y cells. Similarly, RES C-Dots markedly alleviated the secretion of inflammatory factors (TNF-α and IL-1β) promot-ed by 6-OHDA. Furthermore, RES C-Dots prevented apoptosis induced by 6-OHDA by suppressing caspase-3 mRNA expression level.
Conclusions: RES C-Dots rescued SH-SY5Y cells from 6-OHDA- induced damage by modulating the oxido-inflammatory and apoptotic response. This report indicates enounces that RES- synthesised C-Dots may have promising curative potential for PD.
Metakarp Kırıklarının Adli Tıbbi Açıdan Ele Alınması
Authors: ATAN Yusuf , GÜRBÜZ Emre
Published: November 2023

Amaç: El kemik kırıklarının %20'sini beşinci metakarp boyun kırıkları oluşturmaktadır. Genelde yumruk atma neticesinde meydana geldiği için "boksör kırığı" olarak isimlendirilir. Metakarpal kırık meydana gelen kişilerde adli tıbbi yaklaşımın nasıl olması gerektiğinin tartışmaya açılması ve en nihayetinde bu konuda bir uzlaşı zemininin sağlanması amacı ile bu çalışma yapılmıştır. Materyal ve Metod: Çalışma, 2017-2022 yıllarında metakarp kırığı tanısı konularak haklarında adli rapor düzenlenen kişiler arasında yapılmış olup elde edilen veriler (nitel değişkenler) sayı ve yüzde (%) olarak analiz edildi. Bulgular: Çalışmada tamamı erkek olan 15 vaka değerlendirildi. Yaş aralığı 12-68 olup yaş ortalaması 36,26 idi. 11 vakada (%73,33) beşinci metakarpta kırık olup 7 vakada da beşinci metakarp kırığı olan elin dominant el olduğu saptandı. Sonuç: El travması nedeniyle metakarp kırığı tanısı konulan kişilerde direkt mekanizmalar neticesinde beşinci metakarp distali/boynu haricinde de kırık meydana gelebileceği ve Adli Tıp Uzmanı hekimlerin bu noktada anamnez-orijin-muayene-tahkikat dörtlüsü zemininde vakalara yaklaşması gereğinin önemi vurgulanmış olup dominant el faktörü ayrıca kritik edilmiştir.
Modern approaches to the diagnosis of functional disorders of the temporomandibular joint in mandibular trauma
Authors: Khelminskaya N.M. , Kravets A.V. , Pogabalo I.V. , Posadskaya A.V. , Kravets V.I. , Eremin D.A. , Zavgorodnev K.D.
Published: November 2023

This article is devoted to the review of domestic and foreign scientific and clinical works carried out by specialists of various dental specializations, which reflect the study of the features of muscular and maxillary functional disorders associated with trauma of the maxillofacial region with various types of fractures of the lower jaw.
Oscypek na nowo
Authors: Ceklarz Katarzyna
Published: November 2023

Artykuł dotyczy tradycyjnych produktów serowarskich pochodzenia owczego (oscypka, bundzu, a także bryndzy), wykorzystywanych do tworzenia współczesnych dań restauracyjnych. Oparty został na analizie oferty gastronomicznej wiodących podhalańskich restauracji i karczm oraz obserwacji uczestniczącej prowadzonej od wielu lat. Podstawowym celem jest ukazanie z jednej strony możliwości kulinarnych, jakie dają te wyroby mleczarskie (tworzenia nowych, oryginalnych potraw), a z drugiej sposobu kreowania nowoczesnej oferty turystyki kulinarnej pod Tatrami, która z nazwy często jest „tradycyjna”, a w rzeczywistości coraz częściej „foodparingowa”. Przybliżony został także wątek „fałszywych” oscypków nagminnie produkowanych pod Tatrami. W dalszej części tekst omawia zagadnienie inspiracji oscypkiem widocznych m.in. w przemyśle pamiątkarskim, cukierniczym, jubilerskim i modowym, a także w architekturze i wystroju wnętrz. Osobny akapit poświęcono złożonym produktom turystycznym, bazującym na popularności oscypka wśród turystów, takim jak m.in. Muzeum Oscypka w Zakopanem i kulturowe szlaki tematyczne.
Preparation of a freestanding GaN substrate in the Na-flux method by laser-assisted separation
Authors: Hamada Kazuma , Imanishi Masayuki , Murakami Kosuke , Usami Shigeyoshi , Maruyama Mihoko , Yoshimura Masashi , Mori Yusuke
Published: November 2023

We have fabricated large-diameter, high-quality gallium nitride (GaN) substrates by the multipoint seed (MPS) technique in the Na-flux method. To obtain crack-free freestanding GaN crystals, in this study we employed laser-assisted separation (LAS) as a new technique to separate GaN from a sapphire substrate. In LAS, the GaN crystal around the GaN-sapphire interface is partially decomposed by irradiating a laser onto the seed substrate before growth. Since this technique reduces the contact area between the sapphire and GaN, separation occurs spontaneously during the cooling process after growth. We found an appropriate LAS processing pattern for separation and successfully obtained freestanding GaN crystal without cracks. By combining LAS with the MPS method, we succeeded in growing crack-free crystals even in film thicknesses in which cracks occur in conventional MPS substrates.
СТРАТЕГІЇ ТА МОДЕЛІ ФОРМУВАННЯ ЗДОРОВОГО СПОСОБУ ЖИТТЯ В КОНТЕКСТІ ЗДОРОВ’ЯЗБЕРІГАЮЧОЇ ПОВЕДІНКИ
Authors: Чепурко Гульбаршин , Соболєв Андрій
Published: November 2023

Статтю присвячено висвітленню проблеми формування здорового способу життя людини та відповідних соціальних практик здоров’язбереження. Розкрито чинники, які впливають на процес формування здоровʼязберігаючої компетентності, визначено взаємозв’язок між поведінковими стратегіями в сфері здоров’я та моделями формування здорового способу життя. Здоров’язберігаюча компетентність трактується як багатогранний процес формування знань, удосконалення умінь та навичок, набуття досвіду збереження здоров’я, що проявляється у вмінні вести здоровий спосіб життя, в усвідомленому формуванні культури здоров’я та реалізується у здоров’язберігаючій поведінці людини.
Supervised Machine Learning Approach for Predicting Cardiovascular Complications Risk in Patients with Diabetes Mellitus
Authors: Muharram Arief Purnama , Sajid Fahmi
Published: November 2023

Diabetes mellitus, particularly type-2 diabetes, remains a prevalent health issue, raising concerns due to its associated risk of complications. Among these, cardiovascular complications pose a significant threat, exhibiting high morbidity and mortality rates. Health screening plays a pivotal role in stratifying the risk levels of diabetes patients, facilitating proactive measures to prevent the progression of complications. As such, the primary objective of this study is to develop a predictive model system for assessing cardiovascular risk in diabetes patients. Our study used the Cardiovascular Disease dataset and conducts experiments with various supervised machine learning algorithms, such as Naive Bayes, decision tree, random forest, AdaBoost, and XGBoost. The results reveal that ensemble learning algorithms based on boosting, particularly AdaBoost and XGBoost, outperform other supervised machine learning methods. However, even with the best performance achieved using the dataset, the accuracy stands at 0.71, and the F-1 score is 0.69, which is still acceptable for screening purposes. Although these results provide valuable insights, indicating individuals at higher risk for cardiovascular complications in diabetes, further improvements are needed to enhance early prevention strategies.
Clinical IoT in Practice: A Novel Design and Implementation of a Multi-functional Digital Stethoscope for Remote Health Monitoring
Authors: Baraeinejad Bardia , Shams Morteza , Hamedani Mohammad Saberi , Nasiri-Valikboni Amirhossein , Forouzesh Maryam , Fakhraeelotfabadi Shayan , Karimian Radmehr , Babaei Saba , Rashidi Diba , Germchi Danesh , Torabi Yasaman , Gorji Pouya , Vashaee Daryoosh
Published: November 2023

This study introduces a cutting-edge digital stethoscope optimized for
remote health monitoring. Integrating Micro-Electromechanical Systems
(MEMS) microphones with Bluetooth Low Energy (BLE) 5, the device ensures
high-fidelity, real-time audio transmission. It seamlessly connects to
an Internet of Things (IoT) platform through an embedded system,
highlighting its potential in remote healthcare scenarios, especially
during global health emergencies. Advanced features encompass Active
Noise Cancellation, extended battery life, and intricate internal sound
filtration. Paired with a dedicated Android application, the stethoscope
streamlines the capture, storage, and visualization of auscultation
data. Crucially, its integration with Electronic Health Records (EHRs)
and its capability to generate vast datasets can significantly advance
diagnostic precision, leveraging Digital Signal Processing and
Artificial Intelligence methodologies.Â
Supporting collaborative writing tasks in large-scale distance education
Authors: Burchart Marc , Haake Joerg
Published: November 2023

In distance education programs with a large number of students, the organization and facilitation of collaborative writing projects are particularly challenging. Teachers must specify the didactical design and group formation, supervise and support distributed groups, grade, and finally evaluate the learning experiences. Distributed student groups need their own workspace including both, support for a structured writing process including necessary instructions and materials as well as tools for collaborative text editing, communication, coordination, and providing formative and summative feedback. Current approaches to support collaborative writing in education are mostly based on the use of Web 2.0 applications, such as Wikis and Weblogs, or Collaborative real-time text editors, failing to support teachers and students appropriately. As a consequence, teachers often refrain from implementing collaborative writing projects in large scale distance learning courses. We introduce a process model of a collaborative writing project aimed at creating a summary of a research paper and present the architecture and implementation of a Collaborative Learning Platform implementing Collaborative Writing Activities by an extension of a Learning Management System and integrating it with a collaboration environment. The platform supports the phases and activities of the process model and provides distributed teachers and students with integrated support throughout the collaborative writing project lifecycle. Our experience shows that the platform provides a scalable, responsive, and robust environment for collaborative writing and is accepted by teachers and students. It provides the basis for the analysis of collaborative writing behavior and further research.
Performance of a New Dynamic TS Protocol with Intelligent Battery Management in a Full-Duplex Relay Network
Authors: Agrawal Kamal , Prakriya Shankar , Singh Keshav
Published: November 2023

In this paper, the performance of a  two-hop cooperative network is analyzed assuming the use of a channel-aware dynamic time-switching (TS) energy harvesting (EH) protocol at the battery-assisted EH full-duplex relay node. In such networks, node-level energy considerations are important for efficient battery utilization but have not attracted research attention. Two battery management schemes are considered. In the first scheme, fixed  battery energy (FBE) is added to the harvested energy.  To further improve performance, a new dynamic battery energy (DBE) scheme is considered in which the amount of battery energy drawn is channel dependent. The performance of the network is analyzed with both FBE and DBE schemes for static and dynamic TS schemes assuming a practical nonlinear EH model. Expressions are also presented for the average battery energy consumption in each case. It is demonstrated that joint optimization of  the average battery energy consumption and the TS parameter is important. It is also demonstrated that the proposed dynamic TS protocol provides substantial gains in throughput and average energy savings compared to the static TS protocol with both FBE and DBE.  The derived insights can aid a system designer. Computer simulations validate the derived expressions.
Distribution of human gene polymorphisms allele frequencies associated with viral infections
Authors: Vlasenko Natalia V. , Chanyshev Mikhail D. , Dubodelov Dmitriy V. , Serkov Artem A. , Solopova Galina G. , Sacuk Anastasija V. , Snicar Artem V. , Semenenko Tatiana А. , Kuzin Stanislav N. , Akimkin Vasily G.
Published: November 2023

Introduction. The design of studies aimed at finding the association between the genetic factor and the studied feature (disease) involves a comparison of the ratio of genotypes or allelic proportions in the study group with those in the control group. At the stage of determining the ratio of genotypes of the studied polymorphisms in the reference group, researchers meet a number of problems, which are the subject of the present work.
Aim of the work is to provide scientific rationale for the feasibility of creating a national information system comprising genetic data of the relatively healthy population of Russia, incorporating its ethnic diversity.
Materials and methods. The study group, total 1020 people, was genotyped for a number of single nucleotide polymorphisms of human genes. A comparative characteristic of the frequency distribution of the studied polymorphisms with those presented in international databases as reference data was carried out using χ2 index.
Results. The frequency of SNP rs4986790 of the TLR4 gene significantly differs from the EUR population (p = 0.032) and the CEU subpopulation (p = 0.047). The allele frequencies of the rs1800795 (IL6) and rs1800896 (IL10) polymorphisms in the study population differ from the CEU subgroup (p = 0.030 and 0.012, respectively). The frequency of SNP rs2295119 (HLA-DPA2) in the study group is significantly different from the EUR population (p = 0.034).
Conclusion. The analysis carried out in this work confirms the need to create a domestic information system containing data on the occurrence of SNP alleles and genotypes for a conditionally healthy population and in subgroups with various pathological conditions.
Association of polymorphic variants of hemostatic system genes with the course of COVID-19
Authors: Nikolaeva Lyudmila I. , Stuchinskaya Maya D. , Dedova Anna V. , Nadezhda Shevchenko G. , Khlopova Irina N. , Kruzhkova Irina S. , Merkulova Lilya N. , Kisteneva Lidya B. , Kolobukhina Lyudmila V. , Mukasheva Evgenya A. , Krasnoslobodtsev Kirill G. , Trushakova Svetlana V. , Krepkaya Anastasia S. , Kuprianov Victor V. , Nikitenko Natalia A. , Khadorich Elizaveta A. , Burmistrov Egor M. , Tyurin Igor N. , Antipyat Natalia A. , Burtseva Elena I.
Published: November 2023

Introduction. COVID-19 is characterized by a varied clinical course.
The aim of the work was to identify associations of SNPs of hemostatic system genes with COVID-19.
Materials and methods. DNA was isolated from patients (n=117) and healthy participants (n=104). All infected patients were divided into 3 groups, depending on disease severity assessment, which was appreciated by NEWS2. Another group consisted of participants, who had asymptomatic infection in the past. Determination of SNPs of the genes FGB (-455 G/A), FII (20210 G/A), FV (1691 G/A), FVII (10976 G/A), FXIIIA1 (103 G/T), ITGA2 (807 C/T), ITGB3 (1565 T/C), SERPINE1 (-675 5G/4G) were performed by PCR using the “Genetics of Hemostasis” kit (“DNA-Technology”, Russia).
Results. In analyzed SNPs, no significant differences were detected between the group of infected patients and healthy participants. But significant association was revealed in gene SERPINE1 (-675 5G/4G), when patient groups, differing in the disease severity, were analyzed relative to the group of participants with asymptomatic infection (p=0.0381; p=0 .0066; p=0.0009). It was found, that as COVID-19 severity scores increased, the proportion of 5G allele of gene SERPINE1 decreased, and the proportion of the 4G allele increased (p=0.005; p=0.009; p=0.0005). Similar processes were observed for genotypes 5G/5G and 4G/4G.
Discussion. The gene SERPINE1 (-675 5G/4G) is associated with the severity of COVID-19.
Conclusion. For the first time, it was discovered that 5G/5G genotype of gene SERPINE1 (-675 5G/4G) can be a marker of a milder course of COVID-19, and the 4G/4G genotype as a more severe one.
CONTRIBUIÇÕES DAS UNIVERSIDADES À CONSTRUÇÃO DE NOVAS PERSPECTIVAS PARA O BRASIL EM TEMPOS DE PANDEMIAS:
Authors: SÍGOLO Vanessa Moreira , PERCASSI Jade
Published: November 2023

Abstract: Universities have been a space for theoretical formulations and practical experiments, together with social movements and peripheral communities, supporting popular demands and public policies. Faced with the crisis, the increase in unemployment, poverty, hunger and social inequalities, the research deals with the contributions of universities to the construction of prospects for development and social well-being, for a new cycle of national reconstruction in times of pandemics. Among the actions, the initiatives in Emancipatory and Solidarity Economies point to practices of cooperation and care, associated and self-managed work, technological and sustainable practices, little known in society. To contribute to the systematization and dissemination of these actions, as part of research by the Center SoU_Ciência/Unifesp, dedicated to the defense of science and public universities, the research has mapped university extensionist groups and actions in this subject, active in networks and collaborations with society and governments. Through a bibliographical review, selection of sources and interviews with relevant actors at the head of national articulations and in dialogue with public policies, the study seeks to base the creation of a Panel, with a Timeline of actions, Map of initiatives and university networks, thematic glossaries, and bibliometric studies on the subject.
 
Keywords: University; University Extension; Emancipatory and Solidarity Economies; Pandemic; Brazil.
Electronic Attendance System Impact on Healthcare Employees' Performance and Economic Impact in Saudi Arabia
Authors: Abdullah Alshehri Mada , Mohammed Alyami Essam , Abduljabar Alaklabi Mohammed
Published: November 2023

The study concludes that the adoption of electronic attendance systems in Saudi Arabia's healthcare sector has transformed personnel management and brought about a new era characterized by precision, efficacy, and financial constraint. The study highlights the advantages of these solutions, such as enhanced attendance record accuracy, promptness promotion, and better job satisfaction. The study also looks at the financial effects of using computerized attendance systems, such as cost reductions and efficient resource management. Overall, the report highlights how the Saudi Arabian healthcare sector has undergone a revolutionary transition and how electronic attendance systems have been crucial in modernizing the healthcare system.
Evaluation of Concrete Performances Based Recycled Aggregates of Road and Build Demolition for a Formal Using in the Republic of Congo
Authors: Okina Sylvain Ndinga , Ahouet Louis , Etou Destin Gemeton
Published: November 2023

The reuse of recycled aggregates in the composition of concrete is a major challenge today in response to the high cost of construction and the environmental impact of waste This work evaluates the the physic-mechanical properties of concrete using recycled building demolition aggregates and bituminous concrete of pavements in the Republic of Congo. The idea was to check whether these recycled aggregates can have the same performance as when they were first used in concrete. From the results obtained, the recycled building aggregates have good mechanical strength according to the Los Angeles (32.5%) and Micro-Deval (29.3%) tests. Concrete made from building demolition aggregates (CRA1#) has a 28-day compressive strength of (28.8MPa), which is very close to that of the CNA# control concrete (31.11MPa). Concrete incorporating a mixture of asphalt concrete and building demolition aggregates (CRA3#) has a compressive strength of 20.32MPa. In terms of compressive strength, only CRA1# and CRA3# can be used as class C25 concrete for CRA1# and C20 for CRA3#.
Neuroplasticidade e estimulação do Nervo Vago: Revisão Integrativa dos avanços no tratamento da Epilepsia.
Authors: Fernandes do Vale Gustavo , De Queiroz Cunha Leticia , Cardoso Felipe Maria Clara , De Azevedo Assunção Luiz Felipe , Rosado Cantídio Maria Oitava , Marinho Filho Fernando , Rocha Bezerra Keren Suely , Leandro Bezerra Maria Beatriz , Jovino de Oliveira Edson , Fernandes de Holanda Ana Larissa
Published: November 2023

Introdução: A epilepsia refratária representa um desafio na neurologia, afetando a qualidade de vida dos pacientes que não respondem às terapias farmacológicas convencionais. A Estimulação do Nervo Vago (ENV) surge como uma abordagem promissora. Metodologia: Esta revisão integrativa foi baseada em 29 estudos sobre a ENV no tratamento da epilepsia refratária. Utilizou-se a estratégia PICO para a construção da pergunta de pesquisa e os artigos foram selecionados de bases de dados como MEDLINE/PubMed, Science Direct e LILACS. Resultados: A ENV mostrou-se eficaz na redução da frequência das crises epilépticas, com cerca de 8% dos pacientes alcançando liberdade de convulsões. Efeitos colaterais, como cefaleia e irritação da pele, foram leves e bem tolerados. A terapia foi especialmente benéfica para pacientes com síndromes epilépticas específicas. No entanto, o alto custo da ENV pode ser uma barreira para muitos pacientes. Conclusão: A ENV é uma abordagem segura e eficaz para o tratamento da epilepsia refratária. A intervenção precoce pode ser particularmente benéfica, especialmente em pacientes pediátricos. Futuras inovações tecnológicas podem tornar a ENV mais acessível e eficaz.
System Science - An Inclusive Model
Authors: Akbar Khalida , Bodhanya Shamim , Muzekenyi Mike
Published: November 2023

This chapter tries to give a review of the current scientific debates from the point of view of the top scholars in the field. The failure of global South scholars to capitalise on system science research has subsequently identified prevailing western-centric scholarship rooted in western approaches and philosophical traditions. The limited scholarship has resulted in prevailing western dominance and cultural expansionism. The dominant general western scholarship has given rise to a singular scientific system in the 21st century. While system science subscribes to holistic, inter- and trans-disciplinary scholarship, extensive evidence of a hegemonic, exclusivist and monopolistic tradition prevails. this chapter adopts a desk-top approach that sought to collect data and related scientifically compiled evidence. Desktop research encompasses assembling data from prevailing reserves and is preferred as it is cost-effective and considerably less contentious than field research. Dual forms of online desktop research were used. this chapter confronts the dominant reality to make certain that scholars recognise the value systems in which they are firmly rooted.
Re-Engineering Sociological Constellations for Higher Education in South Africa
Authors: Fomunyam Kehdinga George , Ezeonwuachusi Nnenna Fidelia
Published: November 2023

Higher education in South Africa has experienced a number of challenges for the past three decades: from the days of apartheid to post-apartheid South Africa, to the challenges of transforming the higher education landscape. The merger of several South African higher education institutions in 2004 created a plethora of challenges to add to the already existing ones. These challenges were political, sociological, structural and fiscal in nature. The desire to address these challenges has in a way created an epistemological backlog where access to higher education has increased drastically but epistemological access remains a challenge. These amongst other things fuelled the decolonisation movement which demanded for the decolonisation of knowledge. However, the decolonisation of knowledge amongst other things cannot be effective or complete without a re-engineering of the sociology of education. this chapter articulates a pathway for the re-engineering of the sociology of education by articulating four sociological constellations.
Demystifying the Mainstream: Moving from Theories to Stories
Authors: Christopher Adewumi Kehinde
Published: November 2023

Africa, as we have it today, is a direct implication of the researches of the past. Likewise, the future of Africa depends on the quality and relevance of current researches and innovations in education and society. However, in recent years, researchers such as Clegg (2012), Hammond (2018) and Wood, Phan and Wright (2018) have problematized the contemporary relevance and usage of theories in researches. Oftentimes, the impact and understandability of an idea are sacrificed at the altar of theorizing. In such cases, theories and structures are given more attention than the potential impact and contribution of the researcher’s idea. Are theories truly problematic? How do we reconcile the place of theory in contemporary researches and education? How can theorizing be rid of its abstractive tendencies? How can theorizing be decolonized? What are the alternatives to the mainstream approach to theorizing? All these are the questions this chapter seeks to raise and attempt to answer. The argument in this chapter shall be based on Chimamanda Ngozi Adichie’s ideas on storytelling and Sir Ken Robinson’s ideas on seeking creativity as an alternative to rigid adherence to a standardized curriculum.
DIGITAL TRANSFORMATIONS AS INNOVATIVE WAY OF DEVELOPMENT IN THE HOSPITALITY INDUSTRY
Authors:   South Ural State University (Research University), Chelyabinsk, Russia, Bai Tatiana V. , Tarkhanova N. P. ,   South Ural State University (Research University), Chelyabinsk, Russia
Published: November 2023

The increase in the number of enterprises in the hospitality industry puts the issue of increasing competitiveness on the agenda. Digitalization makes it possible to solve the problem of increasing competitiveness comprehensively. However, in the literature, this issue is considered either from the point of view of competitiveness or only the technologies used are considered. The analysis of the literature allowed us to assert that the applied innovations in the hotel business are represented by consumer trends, virtual/augmented reality, smart technologies. The article shows the ways of using a variety of technological innovations to increase competitiveness. The use of various technological innovations allows you to organize a “check-in” service, provide information about the hotel, and perform the functions of a “guest relationship”. In addition, to stimulate the volume of sales of services, manage the revenues of the hotel company and reduce the cost of resource consumption, change the models of human resource management. Along with this, there is an opportunity to offer a variety of novelties that are not presented in other hotels, which increases the attractiveness of the enterprise for the consumer. The use of digital technologies is a costly event. Depending on the tasks and financial capabilities, each company can choose its own option. The difficulties of implementing digital technologies at Russian hotel enterprises are due to economic factors.
METHODOLOGICAL APPROACH TO THE ASSESSMENT OF THE POTENTIAL OF IMPORT SUBSTITUTION IN THE ECONOMY OF THE RUSSIAN FEDERATION AND THE OPPORTUNITIES FOR ITS IMPLEMENTATION. PART 4. ASSESSMENT OF THE CAPABILITIES OF THE PEOPLE’S REPUBLIC OF CHINA TO REALIZE THE POTENTIAL OF IMPORT SUBSTITUTION OF MANUFACTURING PRODUCTS
Authors:   Institute of China and Modern Asia of the Russian Academy of Sciences, Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow Russian Federation, Gordienko Dmitry V.
Published: November 2023

Subject/topic. In the context of the introduction of anti-Russian sanctions for Russia, the task of assessing the potential of import substitution in the economy of the Russian Federation and developing methodological approaches to assessing the possibilities for its implementation becomes especially relevant. Goals/ objectives. Assess the impact of the prospects for expanding trade and economic ties between Russia and China, as well as other countries in the interests of realizing the potential of import substitution in the economy of the Russian Federation in the context of the introduction of anti-Russian sanctions. Methodology. The paper assesses the prospects for expanding trade and economic ties between Russia and China, as well as other countries in the interests of realizing the potential of import substitution in the economy of the Russian Federation in the context of the introduction of anti-Russian sanctions. Results. Based on statistical data, a methodological approach is proposed to assess the potential of import substitution in the economy of the Russian Federation and the possibilities for its implementation, as well as the prospects for expanding trade, economic and investment ties between Russia and China in the context of the introduction of anti-Russian sanctions. Discussion/ application. The proposed methodological approach to assessing the potential of import substitution in the economy of the Russian Federation and the possibilities for its implementation, as well as the prospects for expanding trade, economic and investment relations between Russia and China, makes it possible to predict the implementation of import substitution in the economy of the Russian Federation. Conclusions/relevance. The results of assessing the potential of import substitution in the economy of the Russian Federation and the possibilities for its implementation, as well as the prospects for expanding trade and economic ties between Russia and China in the context of relations between the countries of the “strategic triangle” Russia-China-USA can be used to assess the potential for import substitution of products, works and services in the economy of the Russian Federation and substantiation of recommendations to the leadership of our country. It is concluded that the People’s Republic of China and other countries can realize the commodity and investment potential of import substitution of products in the economy of the Russian Federation.
ANALYSIS OF INVESTMENT DECISION-MAKING FACTORS BY REGIONAL ENTERPRISES
Authors:   VTB Bank PJSC, Irkutsk, Russia, Abbasova Leila R. , Nechaev Andrey S. ,   Irkutsk National Research Technical University, Irkutsk, Russia, Ibragimova Alina V. ,   Irkutsk National Research Technical University, Irkutsk, Russia
Published: November 2023

The article discusses aspects and factors that can play a role in making managerial decisions in regional enterprises. Rational choice of investment direction is necessary for effective financial management, planning and forecasting of economic activity for the long term. The key factors that can influence the adoption of investment decisions are analyzed, the criteria for investment decisions are considered. It is noted that despite the known factors influencing investment decisions, there is a need for additional research and study of the influence of several combined factors on making a proper investment decision, including the nature of information, its disclosure and perception. The authors also proposed a scheme of the investment decision-making process.
ANALYSIS OF FINANCIAL INDICATORS IN INDICATORS AND METRICS FOR ASSESSING THE COMPETITIVE ENVIRONMENT
Authors:   FGAOU HE «North – Caucasian Federal University», Stavropol, Russia, Gorlov Sergei M. , Molchanova Regina V. ,   Saint-Petersburg State University of Aerospace Instrumentation, Saint-Petersburg, Moscow, Russia
Published: November 2023

The article discusses the issues of analyzing financial indicators when assessing the competitive environment, which involves studying the external environment, competitors, threats and opportunities through the tools of indicators and metrics. Financial indicators allow us to identify risks, competitiveness, customer focus, degree of innovation and technological development, marketing efficiency and level of market penetration. The stage-by-stage analysis of the competitive environment is presented through the analysis of financial results, working capital, long-term and short-term financial indicators, and assessment of operating indicators. The features of assessment for some segments of the economy are considered. Attention is paid to the analysis of financial statements as a key tool for assessing the financial condition and competitive environment of an organization, allowing one to identify trends, draw conclusions about the current financial position of the company and predict future results. Financial indicators with a brief description are indicated; the influence of the external competitive environment on financial indicators is presented in tabular form. A practical example of the implementation of market and competitive environment analysis is considered, demonstrating the identification of ineffective processes and structures in an enterprise for the development of effective management strategies and successful functioning in the market.