bluuebunny/crossref_metadata_2025 huggingface dataset:
Status of Compassionate, Respectful, and Caring Health Service Delivery: Scoping Review
Authors: Nigusie Adane , Endehabtu Berhanu F , Angaw Dessie Abebaw , Teklu Alemayehu , Mekonnen Zeleke Abebaw , Feletto Marta , Assan Abraham , Samuel Assegid , Sheikh Kabir , Tilahun Binyam
Published: October 2021

Background

A compassionate, respectful, and caring (CRC) health professional is very important for human-centered care, serving clients ethically and with respect, adhering to the professional oath, and serving as a model for young professionals. As countries try to achieve universal health coverage (UHC), quality delivery of health services is crucial. CRC health care is an initiative around the need to provide quality care services to clients and patients. However, there is an evidence gap on the status of CRC health care service delivery.

Objective

This scoping review aimed to map global evidence on the status of CRC health service delivery practice.

Methods

An exhaustive literature review and Delphi technique were used to answer the 2 research questions: “What is the current status of CRC health care practices among health workers?” and “Is it possible for health professionals, health managers, administrators, and policy makers to incorporate it into their activity while designing strategies that could improve the humanistic and holistic approach to health care provision?” The studies were searched from the year 2014 to September 2020 using electronic databases such as MEDLINE (PubMed), Cochrane Library, Web of Science, Hinari, and the World Health Organization (WHO) library. Additionally, grey literature such as Google, Google Scholar, and WorldWideScience were scrutinized. Studies that applied any study design and data collection and analysis methods related to CRC care were included. Two authors extracted the data and compared the results. Discrepancies were resolved by discussion, or the third reviewer made the decision. Findings from the existing literature were presented using thematic analysis.

Results

A total of 1193 potentially relevant studies were generated from the initial search, and 20 studies were included in the final review. From this review, we identified 5 thematic areas: the status of CRC implementation, facilitators for CRC health care service delivery, barriers to CRC health care delivery, disrespectful and abusive care encountered by patients, and perspectives on CRC. The findings of this review indicated that improving the mechanisms for monitoring health facilities, improving accountability, and becoming aware of the consequences of maltreatment within facilities are critical steps to improving health care delivery practices.

Conclusions

This scoping review identified that there is limited CRC service provision. Lack of training, patient flow volume, and bed shortages were found to be the main contributors of CRC health care delivery. Therefore, the health care system should consider the components of CRC in health care delivery during in-service training, pre-service training, monitoring and evaluation, community engagement, workload division, and performance appraisal.
A Personalized, Interactive, Cognitive Behavioral Therapy–Based Digital Therapeutic (MODIA) for Adjunctive Treatment of Opioid Use Disorder: Development Study (Preprint)
Authors: Meyer Björn , Utter Geri-Lynn , Hillman Catherine
Published: October 2021

BACKGROUND

Opioid use disorder (OUD) is characterized by the inability to control opioid use despite attempts to stop use and negative consequences to oneself and others. The burden of opioid misuse and OUD is a national crisis in the United States with substantial public health, social, and economic implications. Although medication-assisted treatment (MAT) has demonstrated efficacy in the management of OUD, access to effective counseling and psychosocial support is a limiting factor and a significant problem for many patients and physicians. Digital therapeutics are an innovative class of interventions that help prevent, manage, or treat diseases by delivering therapy using software programs. These applications can circumvent barriers to uptake, improve treatment adherence, and enable broad delivery of evidence-based management strategies to meet service gaps. However, few digital therapeutics specifically targeting OUD are available, and additional options are needed.

OBJECTIVE

To this end, we describe the development of the novel digital therapeutic MODIA.

METHODS

MODIA was developed by an international, multidisciplinary team that aims to provide effective, accessible, and sustainable management for patients with OUD. Although MODIA is aligned with principles of cognitive behavioral therapy, it was not designed to present any 1 specific treatment and uses a broad range of evidence-based behavior change techniques drawn from cognitive behavioral therapy, mindfulness, acceptance and commitment therapy, and motivational interviewing.

RESULTS

MODIA uses proprietary software that dynamically tailors content to the users’ responses. The MODIA program comprises 24 modules or “chats” that patients are instructed to work through independently. Patient responses dictate subsequent content, creating a “simulated dialogue” experience between the patient and program. MODIA also includes brief motivational text messages that are sent regularly to prompt patients to use the program and help them transfer therapeutic techniques into their daily routines. Thus, MODIA offers individuals with OUD a custom-tailored, interactive digital psychotherapy intervention that maximizes the personal relevance and emotional impact of the interaction.

CONCLUSIONS

As part of a clinician-supervised MAT program, MODIA will allow more patients to begin psychotherapy concurrently with opioid maintenance treatment. We expect access to MODIA will improve the OUD management experience and provide sustainable positive outcomes for patients.
A Web-Based, Time-Use App To Assess Children’s Movement Behaviors: Validation Study of My E-Diary for Activities and Lifestyle (MEDAL) (Preprint)
Authors: Tan Sarah Yi Xuan , Chia Airu , Tai Bee Choo , Natarajan Padmapriya , Goh Claire Marie Jie Lin , Shek Lynette P , Saw Seang Mei , Chong Mary Foong-Fong , Müller-Riemenschneider Falk
Published: October 2021

BACKGROUND

Existing modes of collecting self-reported 24-hour movement information from children, including digital assessments, have not been demonstrated to be of acceptable validity when compared to objective measurements. My E-Diary for Activities and Lifestyle (MEDAL) is an interactive web-based diary developed to collect time-use information from children aged 10 years and older.

OBJECTIVE

This study evaluated the validity of MEDAL for assessing children’s movement behaviors by comparing self-reported and accelerometer-measured time spent in movement behavior among children in Singapore aged 10-11 years.

METHODS

Funding for this study was obtained in October 2017, and data were collected between April and August 2020. Participants recorded their daily activities using MEDAL over 2 specified weekdays and 2 weekend days and wore an Actigraph accelerometer on their nondominant wrist throughout the study to objectively assess movement behaviors. Spearman correlation coefficient and intraclass correlation coefficient (ICC) were used to compare the accelerometer measurements and self-reports for each movement behavior. Bland-Altman plots were generated to investigate trends of bias in the self-reports.

RESULTS

Among the participants aged 10-11 years (29/49, 59% boys), we observed that children reported lower light physical activity (LPA) and higher moderate-to-vigorous physical activity (MVPA), inactivity, and night sleep than that measured by the accelerometer. There was a moderate-to-strong correlation between self-reported and accelerometer-measured MVPA (r=0.37; 95% CI 0.20-0.54), inactivity (r=0.36; 95% CI 0.18-0.54), and night sleep (r=0.58; 95% CI 0.43-0.74); the correlation for LPA was poor (r=0.19; 95% CI 0.02-0.36). Agreement was poor for all behaviors (MVPA: ICC=0.24, 95% CI 0.07-0.40; LPA: ICC=0.19, 95% CI 0.01-0.36; inactivity: ICC=0.29, 95% CI 0.11-0.44; night sleep: ICC=0.45, 95% CI 0.29-0.58). There was stronger correlation and agreement on weekdays for inactivity and night sleep; conversely, there was stronger correlation and agreement for MVPA and LPA on weekend days. Finally, based on Bland-Altman plots, we observed that with increasing MVPA, children tended to report higher MVPA than that measured by the accelerometer. There were no clear trends for the other behaviors.

CONCLUSIONS

MEDAL may be used to assess the movement behaviors of children. Based on self-reports, the children are able to estimate their time spent in MVPA, inactivity, and night sleep although actual time spent in these behaviors may differ from accelerometer-derived estimates; self-reported LPA warrant cautious interpretation. Observable differences in reporting accuracy exist between weekdays and weekend days.
Development and assessment of an accessible communication system for population-based genetic testing: Method/design (Preprint)
Authors: Coffin Tara , Bowen Deborah , Swisher Elizabeth , Lu Karen , Lu Karen , Lu Karen , Rayes Nadine , Norquist Barbara , Norquist Barbara , Norquist Barbara , Blank Stephanie , Levine Douglas , Levine Douglas , Levine Douglas , Bakkum-Gamez Jamie , Bakkum-Gamez Jamie , Bakkum-Gamez Jamie , Bakkum-Gamez Jamie , Fleming Gini , Fleming Gini , Olopade Olofunmi , Olopade Olofunmi , Olopade Olofunmi , D’Andrea Alan , D’Andrea Alan , Nebgen Denise , Nebgen Denise , Nebgen Denise , Nebgen Denise , Peterson Christine , Peterson Christine , Peterson Christine , Munsell Mark , Gavin Kathleen , Gavin Kathleen , Lechner Rebecca , Lechner Rebecca , Crase Jamie , Crase Jamie , Polinsky Deborah , Romero Iris
Published: October 2021

BACKGROUND

Genetic testing uptake is low, despite the well-established connection between pathogenic variants in certain cancer-linked susceptibility genes and ovarian cancer risk. Given that most major insurers cover genetic testing for those with a family history suggestive of hereditary cancer, the issue may lie in access to genetic testing.

OBJECTIVE

To present the development and formative evaluation of the multi-step online communication system required to support the democratization of genetic testing.

METHODS

While designing the multi-step online communication system, we considered various barriers and facilitators to genetic testing, guided by Levesque et al.’s dimensions of accessibility. In addition to conducting usability testing, we performed ongoing assessments focusing on function of the online system and participant response rates, with the goal of continuing to make modifications to the online communication system as it is in use.

RESULTS

The combined approach of usability testing and expert user experience (UX) consultation resulted in several modifications to the multi-step online communication system, including changes that related to imagery and content, web-accessibility, and general organization of the online system. All recommendations were made with the goal of improving the overall accessibility of the online communication system.

CONCLUSIONS

A multi-step online communication system appears to be an effective way to address many potential barriers to access, which may otherwise make genetic testing difficult for at-risk individuals to participate in. Importantly, some dimensions of access were easy to assess prior to study recruitment opening, but other aspects of the communication system required ongoing assessment during the implementation process of the Making Genetic Testing Accessible (MAGENTA) study.
Understanding Cardiology Practitioners’ Interpretations of Electrocardiograms: An Eye-Tracking Study (Preprint)
Authors: Tahri Sqalli Mohammed , Al-Thani Dena , Elshazly Mohamed B , Al-Hijji Mohammed , Alahmadi Alaa , Sqalli Houssaini Yahya
Published: October 2021

BACKGROUND

Visual expertise refers to advanced visual skills demonstrated when performing domain-specific visual tasks. Prior research has emphasized the fact that medical experts rely on such perceptual pattern-recognition skills when interpreting medical images, particularly in the field of electrocardiogram (ECG) interpretation. Analyzing and modeling cardiology practitioners’ visual behavior across different levels of expertise in the health care sector is crucial. Namely, understanding such acquirable visual skills may help train less experienced clinicians to interpret ECGs accurately.

OBJECTIVE

This study aims to quantify and analyze through the use of eye-tracking technology differences in the visual behavior and methodological practices for different expertise levels of cardiology practitioners such as medical students, cardiology nurses, technicians, fellows, and consultants when interpreting several types of ECGs.

METHODS

A total of 63 participants with different levels of clinical expertise took part in an eye-tracking study that consisted of interpreting 10 ECGs with different cardiac abnormalities. A counterbalanced within-subjects design was used with one independent variable consisting of the expertise level of the cardiology practitioners and two dependent variables of eye-tracking metrics (fixations count and fixation revisitations). The eye movements data revealed by specific visual behaviors were analyzed according to the accuracy of interpretation and the frequency with which interpreters visited different parts/leads on a standard 12-lead ECG. In addition, the median and SD in the IQR for the fixations count and the mean and SD for the ECG lead revisitations were calculated.

RESULTS

Accuracy of interpretation ranged between 98% among consultants, 87% among fellows, 70% among technicians, 63% among nurses, and finally 52% among medical students. The results of the eye fixations count, and eye fixation revisitations indicate that the less experienced cardiology practitioners need to interpret several ECG leads more carefully before making any decision. However, more experienced cardiology practitioners rely on their skills to recognize the visual signal patterns of different cardiac abnormalities, providing an accurate ECG interpretation.

CONCLUSIONS

The results show that visual expertise for ECG interpretation is linked to the practitioner’s role within the health care system and the number of years of practical experience interpreting ECGs. Cardiology practitioners focus on different ECG leads and different waveform abnormalities according to their role in the health care sector and their expertise levels.
Refinement of a Parent–Child Shared Asthma Management Mobile Health App: Human-Centered Design Study (Preprint)
Authors: Sonney Jennifer , Cho Emily E , Zheng Qiming , Kientz Julie A
Published: October 2021

BACKGROUND

The school-age years, approximately ages 7 through 11, represent a natural transition when children begin assuming some responsibility for their asthma management. Previously, we designed a theoretically derived, tailored parent–child shared asthma management mobile health app prototype, Improving Asthma Care Together (IMPACT).

OBJECTIVE

The purpose of this study was to use human-centered design (HCD) to iteratively refine IMPACT to optimize user experience and incorporate evidence-based longitudinal engagement strategies.

METHODS

This study used a mixed methods design from December 2019 to April 2021. Our app refinement used the HCD process of research, ideation, design, evaluation, and implementation, including 6 cycles of design and evaluation. The design and evaluation cycles focused on core app functionality, child engagement, and overall refinement. Evaluation with parent–child dyads entailed in-person and remote concept testing and usability testing sessions, after which rapid cycle thematic analyses identified key insights that informed future design refinement.

RESULTS

Twelve parent–child dyads enrolled in at least one round of this study. Eight of the 12 child participants were male with a mean age of 9.9 (SD 1.6) years and all parent participants were female. Throughout evaluation cycles, dyads selected preferred app layouts, gamification concepts, and overall features with a final design prototype emerging for full-scale development and implementation.

CONCLUSIONS

A theoretically derived, evidence-based shared asthma management app was co-designed with end users to address real-world pain points and priorities. An 8-week pilot study testing app feasibility, acceptability, and preliminary efficacy is forthcoming.
Thoughts from French Psychoanalysis on the Absence of Corporeality in the Unconscious of Emerging Complex Cognitive System
Authors: GUY Olivier , Potier Rémy
Published: October 2021

In this text we answer at the same time to two recent interesting works of Giancarlo Minati and Luca Possati in which they both called to work on the development, one from the part of the computer side, and the other of the humanities one of an IA unconscious in complex cognitive systems as an experiment to come to more anthropomorphic machines, performance added by the unconscious will not be addressed in this paper. We gathered many sources in psychoanalysis to help us understand what could be the barriers dressed against us. In the light of Lacan, Anzieu, Leclaire and Winnicott amongst others we tried to explain how having a body, in the biological sense, makes a difference with recreating—this is a typical human preoccupation—an unconscious in IA. Of course, from a French psychoanalytic standpoint there are many conservative objections, while some can be easily overcome, the matter of innate desire and body seems an understandable concern. It is also important to consider the interesting conjecture of Possati (i.e., a computer can be a projective identification object); while we only may say that it is a transitional object in the sense of Winnicott. Also, we can study further within psychotherapy the behaviour of the patient and therapist, with an algorithm we developed. In the end we address the objection of French postructruralist psychology objections to the creation of a human-like unconscious and advise the experimenting of Possati’s theory with our device.
A 21st Century Vision for Neotropical Snake Systematics
Authors: Pyron Robert Alexander
Published: October 2021

We live in an unprecedented age for systematics and biodiversity studies. Ongoing global change is leading to a future with reduced species richness and ecosystem function (Pereira, Navarro, & Martins, 2012). Yet, we know more about biodiversity now than at any time in the past. For squamates in particular, we have range maps for all species (Roll et al., 2017), phylogenies containing estimates for all species (Tonini, Beard, Ferreira, Jetz, & Pyron, 2016), and myriad ecological and natural-history datasets for a large percentage of species (Meiri et al., 2013; Mesquita et al., 2016). For neotropical snakes, a recent synthesis of museum specimens and verified localities offers a fine-grained perspective on their ecogeographic distribution in Central and South America, and the Caribbean (Guedes et al., 2018).
ANOMALÍAS MACROSCÓPICAS EN LARVAS DE ANFIBIOS ANUROS
Authors: Aguillón-Gutiérrez David Ramiro
Published: October 2021

Actualmente, los anfibios son el grupo de vertebrados más amenazados a nivel mundial, pues algunos autores consideran que de un 30 a un 40% de especies dentro de este grupo, están en riesgo de extinción. El problema es multifactorial y global, pues es la combinación de distintos factores lo que pone en riesgo a un gran número de especies en muchas partes del mundo a la vez (Blaustein y Wake, 1995; Young et al. 2001; Stuart et al., 2004; Allentoft y O’Brien, 2010).

Aunque a partir de que empezó la llamada “crisis de los anfibios” aumentó considerablemente el número de investigaciones y publicaciones sobre este grupo biológico, sigue habiendo muchos lugares, especies y factores que no han sido estudiados. Por ejemplo, las larvas de anfibios han sido históricamente menos estudiadas que los adultos, pues son más difíciles de encontrar, de identificar y de investigar (McDiarmind y Altig 1999).

En países con una gran biodiversidad como México, gran parte de los estudios en ciencias biológicas y ecológicas se centran en la taxonomía y distribución de las especies, y en menor medida se abordan temas relacionados a la salud de los organismos.

A nivel mundial, existe un número importante de publicaciones sobre anomalías macroscópicas en anfibios, aunque la gran mayoría se hizo en individuos adultos, lo que reduce el espectro de tipos de anomalías encontrados, ya que, en etapa larvaria, muchos de los individuos con anomalías presentes no llegarán a la etapa adulta (Johnson et al. 2001, Blaustein y Johnson 2003).

Las anomalías macroscópicas son aquellas que se pueden observar a simple vista en la parte externa del organismo. Se considera que no más de un 5% de una población de anfibios debe presentar una anomalía (Blaustein y Johnson 2003), sin embargo, hay reportes de poblaciones las cuales superan ese porcentaje (Vershinin 1989, Severtsova et al. 2012b), lo que indica que existen uno o varios factores que propician este fenómeno.

En este capítulo se abordan los tipos de anomalías macroscópicas en larvas de anfibios anuros, no sin antes dar una breve explicación sobre los anfibios, sus etapas ontogenéticas y su conservación. La sección de anomalías empieza con la terminología básica y posteriormente se divide según la etiología de las mismas, abarcando factores genéticos, agentes infecciosos, factores ambientales, exposición a contaminantes y anomalías por factores desconocidos. Finalmente se presentan las conclusiones y la bibliografía. Como se puede apreciar, el objetivo de este trabajo es ofrecer un panorama general de este interesante fenómeno, esperando cumplir con las expectativas del lector.
Anfibios y Reptiles: enfermedades, hospederos y vectores
Authors: Herpetologia Revista Latinoamericana de
Published: October 2021

Editorial Invitada.
Magic Symbols (Charaktêres) on North African Curse Tablets as a Regional Feature
Authors: Németh György
Published: October 2021

This study examines the practice of magic symbols in North Africa to find out whether there was a regional peculiarity in the use of charaktêres that distinguished this area from other parts of the Roman Empire. Two phenomena appear to be more common in North Africa, though they may also occur elsewhere: first, charaktêres as encrypted names, and second, charaktêres as framing devices. First and foremost, though, some introductory remarks concerning charaktêres in general are made.
Presence and Importance of Beauty in the Byzantine Epigrams About the Cross and the Crucifixion of Jesus Christ: Some Basic Observations
Authors: Kantaras Anastasios
Published: October 2021

Scholar poetry, particularly the epigram, has been a literary means of expression not only of ideas and attitudes about life but also of religious sentiment and profound religious faith. Delving into the epigrams of the second category, particularly those related to the Cross and the Crucifixion, our attention will be focused on the presence of beauty, its meaning, and the role it played within the category of Byzantine epigrams. The aim of this article is to identify relevant epigrams (by anonymous or known writers), make some basic observations and reach certain conclusions regarding the issue of beauty.
Magical Iconography. How Can an Image Protect and Heal?
Authors: First Grzegorz
Published: October 2021

One of the features of the attitude of ancient societies towards the threats of everyday life was a close relationship between spiritual/magical and religious beliefs and the real actions aimed at overcoming dangers. This relationship is visible in the magical iconography of Ancient Egypt and other Ancient Near Eastern cultures – in the form of demons, minor deities, and other benevolent supernatural beings that can protect people. Images of theses deities are sometimes accompanied by archaeological traces (holes for water, traces of rubbing, touching), indicating that images were also subjects of action. The question is how the magical and religious iconography meets the non-supernatural actions and how this custom could emerge in other parts of the Ancient world and in post-ancient times.
pied de Sérapis de la sculpture à l’intaille : étude d’un thème isiaque caractéristique
Authors: Barcat Dominique
Published: October 2021

The so-called foot of Serapis sculptures (i.e. those in the round with a bust of Serapis directly on top of a right foot) are well known and studied. Nevertheless, it was still necessary to take into account the representations of this motif in other media, such as gems and coins. And that is precisely the purpose of the present paper. In the following pages, these images are analyzed in the iconographical context of their period (1st and 2nd centuries CE). Such an approach allows us to observe the development of the motif in the different materials. In addition, this analysis will help us better understand the meaning of this image, and also to formulate some theories concerning the possible uses of these gems.
SUSTAINABLE DEVELOPMENT GOALS TO STRENGTHEN INDONESIAN PALM OIL DEVELOPMENT THROUGH INDONESIAN SUSTAINABLE PALM OIL (ISPO)
Authors: Fahamsyah Ermanto , Amalia Rama Wulandari Brigitta , Adiwibowo Yusuf
Published: October 2021

The palm oil development provides many advantages for Indonesia. One of which is that the development of Indonesian palm oil came fast and contributed a lot to the country's economic sectors. There are also other organic oil-based, such as jatropha, camelina, soybean and rapeseed. However, compared the palm oil to the other base of the organic oil materials, palm oil price outperforms the others oil-based because of the stability of the palm oil price. Palm oil benefits the Indonesian economy and the triple bottom line of John Elkington: people, planet, and profit. However, there is a critical issue with palm oil production. Its production is believed not to apply sustainability principles. Thus, it can damage and ruin the natural environment in Indonesia; for example, it damaged the area where the Sumatran tiger, Sumatran Orang Utan, and Borneo Orang Utan lived. Through the ministry of agriculture, the government established Indonesian Sustainable Palm Oil (ISPO) to answer this critical issue and recover the sustainability aspect of Indonesian palm oil.

Abstrak: Indonesia beruntung karena dapat menikmati berbagai manfaat dari pembangunan kelapa sawit yang merupakan salah satu ciri dan keuntungan tersendiri yang Indonesia miliki, pembangunan kelapa sawit Indonesia sangat cepat dan pesat serta memberikan kontribusi yang tinggi terhadap negara melalui sektor ekonomi, jika dibandingkan dengan minyak nabati lainnya seperti : jathropa, camelina, soy bean dan rapeseed, kelapa sawit lebih unggul dari segi ekonomi yang mana dari segi harga lebih stabil jika dibandingkan minyak nabati dengan bahan baku lainnya. Minyak kelapa sawit memberikan berbagai manfaat bagi Indonesia selain daripada ekonomi juga terhadap triple bottom line sebagaimana dikemukakan oleh John Elkongton yakni people, planet dan profit sehingga dalam pemanfaatannya memberikan dampak yang baik meski begitu tetap saja dihadapkan dengan berbagai critical issue mengenai kelapa sawit. Dalam kegiatan produksi kelapa sawit diyakini bahwa belum mengedepankan aspek keberlanjutan yang kemudian berdampak terhadap kerusakan lingkungan di Indonesia.

Kata Kunci: Indonesia, ISPO, Pembangunan Kelapa Sawit, Aspek Keberlanjutan, Triple Bottom Line
Reception of Dostoevsky’s Artistic Heritage in the Works of Italian Writers at the Turn of the 19th–20th Centuries
Authors:   Moscow State Psychological and Pedagogical University, Dergacheva Irina V.
Published: October 2021

At present, there is no doubt about the recognition and high assessment of the artistic, journalistic and epistolary heritage of F.M. Dostoevsky in Italian culture and literary criticism. S. Aloe described in detail the difficult process of acquaintance of Italian Slavists and writers with the work of Dostoevsky, complicated for a number of years by the lack of translations of his works into Italian — readers could only get acquainted with French translations of his texts [Aloe]. The readers’ notes in the Viesse Cabinet in Florence, which allowed researchers to get acquainted with the writer’s reading circle, after 1881, the year of the writer’s death, showed the growing interest of Italian readers and foreign travelers to the works of Dostoevsky. The article analyzes the reception of the ideological and artistic heritage of F.M. Dostoevsky in the works of Italian writers, representatives of the verist movement, Gabriele D’Annunzio, Luigi Capuana and Grazia Deledda, at the turn of the 19th and 20th centuries.
Dostoevsky’s Petersburg in the Story by G.I. Chulkov “Autumn Mists” (1916)
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Bogdanova Olga A.
Published: October 2021

The article examines the metamorphoses of the image of St. Petersburg created in the works of F.M. Dostoevsky, in the literature of the Silver age, in particular in the half-forgotten, but significant story of a major symbolist writer G.I. Chulkov “Autumn mists” (1916). It is shown that, on the one hand, Chulkov’s artistic experience is intertwined with the general trend of “rewriting the classics” for the Silver age, which was first noted by D.M. Magomedova, at the same time on the other — proved that “Autumn mists”, is primarily focused not on the “great five books” of Dostoevsky with the hero-ideologist in the center of each piece, and the synthetic image of St. Petersburg in the novel “Humiliated and offended” (1861), incorporates the positive connotations early works of the famous classics and accusatory — late, are the most complete polemical conclusion cultural dialogue with Dostoevsky at the end of the “Petersburg period” of Russian history. It is pointed out that Dostoevsky’s mythologized images were transformed into elements of symbolist and, more broadly, modernist poetics, as well as the rejection of psychologism and the reinterpretation of the writer’s historiosophical prophecies of the 19th century. Thus, “Autumn mists” is a restored link of the “Petersburg text” of Russian literature at the break of cultural and historical epochs, which, in the context of famous works on the same subject by I.F. Annensky, D.S. Merezhkovsky, A. Bely, A.A. Blok, and others of Chulkov’s contemporaries, has an indisputable value due to the many-sided meanings contained in it.
Convergence to diffusion waves for solutions of 1D Keller-Segel model
Authors: Liu Fengling , Zhang Nangao , Zhu Changjiang
Published: October 2021

In this paper, we are concerned with the asymptotic behavior of
solutions to the Cauchy problem (or initial-boundary value problem) of
one-dimensional Keller-Segel model. For the Cauchy problem, we prove
that the solutions time-asymptotically converge to the nonlinear
diffusion wave whose profile is self-similar solution to the
corresponding parabolic equation, which is derived by Darcy’s law, as in
[11, 28]. For the initial-boundary value problem, we consider two
cases: Dirichlet boundary condition and null-Neumann boundary condition
on (u, ρ). In the case of Dirichlet boundary condition, similar to the
Cauchy problem, the asymptotic profile is still the self similar
solution of the corresponding parabolic equation, which is derived by
Darcy’s law, thus we only need to deal with boundary effect. In the case
of null-Neumann boundary condition, the global existence and asymptotic
behavior of solutions near constant steady states are established. The
proof is based on the elementary energy method and some delicate
analysis of the corresponding asymptotic profiles.
Multigenerational exposure to increased temperature reduces metabolic rate but increases boldness
Authors: Moffett Emma , Fryxell David , Simon Kevin
Published: October 2021

Acute exposure to warming temperatures increases minimum energetic
requirements in ectotherms. However, over and within multiple
generations, increased temperatures may cause plastic and evolved
changes that modify the temperature sensitivity of energy demand and
alter individual behaviours. Here, we aimed to test whether populations
recently exposed to geothermally elevated temperatures express an
altered temperature sensitivity of metabolism and behaviour. We expected
that long-term exposure to warming would moderate metabolic rate,
reducing the temperature sensitivity of metabolism, with concomitant
reductions in boldness and activity. We compared the temperature
sensitivity of metabolic rate (acclimation at 20 versus 30°C) and
allometric slopes of routine, standard, and maximum metabolic rates, in
addition to boldness and activity behaviours, across eight recently
divergent populations of a widespread fish species (Gambusia affinis).
Our data reveal that warm-source populations express a reduced
temperature sensitivity of metabolism, with relatively high metabolic
rates at cool acclimation temperatures and relatively low metabolic
rates at warm acclimation temperatures. Allometric scaling of metabolism
did not differ with thermal history. Across individuals from all
populations combined, higher metabolic rates were associated with higher
boldness and activity. However, warm-source populations displayed
relatively more bold behaviour at both acclimation temperatures, despite
their relatively low metabolic rates at warm acclimation temperatures.
Overall, our data suggest that in response to warming, multigenerational
processes may not direct trait change along a simple “pace-of-life
syndrome” axis, instead causing relative decreases in metabolism and
increases in boldness. Ultimately, our data suggest that
multigenerational warming may produce a novel combination of
physiological and behavioural traits, with consequences for animal
performance in a warming world.
CENTRAL DIABETES INSIPIDUS AFTER ABDOMINAL SURGERY: A CASE REPORT
Authors: Maharaj Aarti , Jana Kundan , Janga Kalyana , Greenberg Sheldon , Fein Elie
Published: October 2021

Post-operative polyuria due to Diabetes Insipidus is a commonly reported
complication of pituitary surgery. However, central DI post abdominal
surgery is rare and may be related to pre-existing DI or prolonged
surgery with intraoperative blood loss. A thorough workup needs to be
done to exclude central DI in such patients.
PhenomeCentral: 7 years of rare disease matchmaking
Authors: Osmond Matthew , Hartley Taila , Johnstone Brittney , Andijc Sasha , Girdea Marta , Gillespie Meredith , Buske Orion , Dumitriu Sergiu , Koltunova Veronika , Ramani Arun , Boycott Kym , Brudno Michael
Published: October 2021

A major challenge in validating genetic causes for patients with rare
diseases (RDs) is the difficulty in identifying other RD patients with
overlapping phenotypes and variants in the same candidate gene. This
process, known as matchmaking, requires robust data sharing solutions in
order to be effective. In 2014 we launched PhenomeCentral, a RD data
repository capable of collecting computer-readable genotypic and
phenotypic data for the purposes of RD matchmaking. Over the past 7
years PhenomeCentral’s features have been expanded and its dataset has
consistently grown. There are currently 1,615 users registered on
PhenomeCentral, which have contributed over 12,000 patient cases. Most
of these cases contain detailed phenotypic terms, with a significant
portion also providing genomic sequence data or other forms of clinical
information. Matchmaking within PhenomeCentral, and with connections to
other data repositories in the Matchmaker Exchange, have collectively
resulted in over 60,000 matches, which have facilitated multiple gene
discoveries. The collection of deep phenotypic and genotypic data has
also positioned PhenomeCentral well to support next generation of
matchmaking initiatives that utilize genome sequencing data, ensuring
that PhenomeCentral will remain a useful tool in solving undiagnosed RD
cases in the years to come.
Implementasi dan modifikasi WebShell untuk monitoring serangan berbasis website
Authors: Gumilang Paulus Miki Resa , Chandra Dian Widiyanto
Published: October 2021

Backdoor is a code commonly used by hackers to gain access to a web page illegally, backdoor or also called a webshell at this time is still very often used by hackers to carry out attacks on a web page, but in handling attacks using a webshell it is not always possible to detected quickly and even take months to realize the web page has embedded webshell. To deal with these problems, we need an application that can quickly detect attacks carried out by embedding a webshell on a web page. The purpose of this study is to modify an existing webshell so that it can be monitored when used by hackers to attack a website, the monitoring process is carried out using a web page created by the author. The results of the discussion of this study can be used to quickly detect attacks that using modified webshell.
Suriyeli sığınmacı kadınların sözlü anlatılarında savaş, göç ve evlilik
Authors: HARUNOĞULLARI Muazzez
Published: October 2021

Çalışmanın amacı, Suriyeli kadınların savaş dolayısıyla yaşanan göçün yaşamları üzerindeki etkileri ile gündelik yaşam ve evlilik deneyimlerini değerlendirmektir. Çalışma, kartopu örnekleme yöntemi kullanılarak yapılmıştır. Bu yöntemle, Türkiye’nin sınır ili olan Kilis şehrinde yaşayan ve Türk erkeklerle evlilik yapan 15 katılımcıya ulaşılmıştır. Veriler, katılımcılardan derinlemesine görüşme ve katılımcı gözlem tekniği ile elde edilmiştir. Savaşın kadınların yaşamında ve psikolojilerinde meydana getirdiği etkiler oldukça derindir. Savaşta ailesini veya eşini kaybeden ya da savaşın yarattığı tüm olumsuz şartlarla baş etmek zorunda kalan kadınlar hayata tutunabilmek, güvenliklerini sağlamak, ekonomik anlamda rahatlamak, kendilerini bir yere ait hissetmek için Türk erkekleriyle evlilik yapmayı tercih etmiştir.
Distance Between Two Keplerian Orbits
Authors: Mohamed Ayman Homda , Dwidar Hany Ramdan , Adham Inal , Bakry Abd-Elazaz , El-Raffie Ahmed
Published: October 2021

In this paper, constrained minimization for the point of closest approach of two conic sections is developed. For this development, we considered the nine cases of possible conics, namely, (elliptic–elliptic), (elliptic–parabolic), (elliptic–hyperbolic), (parabolic–elliptic), (parabolic–parabolic), (parabolic–hyperbolic), (hyperbolic–elliptic), (hyperbolic–parabolic), and (hyperbolic–hyperbolic). The developments are considered from two points of view, namely, analytical and computational. For the analytical developments, the literal expression of the minimum distance equation (S) and the constraint equation (G), including the first and second derivatives for each case, are established. For the computational developments, we construct an efficient algorithm for calculating the minimum distance by using the Lagrange multiplier method under the constraint on time. Finally, we compute the closest distance S between two conics for some orbits. The accuracy of the solutions was checked under the conditions that L|
solution
≤ ɛ1; G|
solution
≤ ɛ2, where ɛ1,2 < 10−10. For the cases of (parabolic–parabolic), (parabolic–hyperbolic), and (hyperbolic–hyperbolic), we studied thousands of comets, but the condition of the closest approach was not met.
Impact of the implementation of EU, national and local policies and legislation on the transition towards eco-cities in Poland
Authors: Kociuba Dagmara , Wajs Klaudia
Published: October 2021

Transforming cities towards eco-cities constitutes a significant effort in mitigating and adapting to climate change. The implementation of legal acts and diverse environmentally oriented sectoral policies plays an important role in that process. The objective of this paper is to determine the antecedences and effects of the transformation of cities in accordance with the eco-city concept in Poland in the context of implemented policies, legislation and initiatives. The study reviews the normative acts and programme-strategic documents that provide the framework for the shift towards eco-city at the international and EU level, as well as identifying changes in legislation and policy initiatives resulting from their implementation at national and local level. A set of 24 original indices referring to six aspects of the eco-city (waste management, water and wastewater management, transport and urban mobility, application of RES in energy engineering, air quality, and urban green areas) were applied in multi-criterion analyses in selected case studies. This permitted us to identify the key factors that power the transition towards eco-city. The legal and policy measures are implemented in a top-down approach. Actions are usually initiated at national level and implemented by local authorities, who operate according to their assigned tasks and using dedicated tools (e.g. LEPs, SUMPs). Significant effect of the implementation of eco-city solutions were identified in waste management, sustainable transport, urban mobility, and air quality improvement. Recommendations for future measures include implementing plans and demonstrative projects of eco-cities or eco-districts, conducting complex pro-ecological measures, and increasing the role of bottom-up actions.
Susac syndrome with cognitive impairment - case report of 31-year-old woman
Authors: Terpiłowski Michał , Terpiłowska Barbara , Orzeł Anna , Szlichta Dominika , Łata Marcin , Próchnicki Michał
Published: October 2021

Introduction: Susac syndrome (SuS) is a rare immune-mediated disease caused by occlusions of microvessels in the brain, retina and inner ear. It is characterized by the clinical triad of encephalopathy, visual disturbances and hearing loss. The diagnosis of SuS is based mainly on the clinical symptoms and the supporting tests in which characteristic changes occur in the MRI.

Case report: Here, we present a case of a patient with possible SuS with psychiatric symptoms. A 31-year-old woman was admitted to the Department of Psychiatry due to deteriorating mental health for several weeks manifested as a negative mood and suicidal thoughts. During hospitalization, a neurological consultation was conducted, in which the patient was identified as conscious, psychomotor sluggish, with impaired verbal contact and persistent hearing and vision impairment. Cross-sectional assessment of cognitive functions revealed that the patient had a generalized syndrome of neuropsychological deficits, which confirms the diagnosis of dementia.

Discussion: This case summary provides an example of a woman diagnosed with SuS manifested as a cognitive impairment with associated vision and hearing deterioration. It is worth emphasizing the fact that such presentation of the triad of at disease onset is rare. The characteristics of the organic changes in the brain described in the MRI probably explain the symptoms described in that case. The prognosis of SuS depends on early diagnosis and treatment.

Conclusions: A diagnosis of SuS should always be considered in the presence of nonspecific neuropsychiatric symptoms and progressive multifocal neurological symptoms, hearing loss, and visual impairment. An important fact is that the typical triad of SuS symptoms in most cases does not occur simultaneously, which makes the diagnostic process very difficult and may lead to misdiagnosis.
A Probabilistic-Based Portfolio Resampling Under the Mean-Variance Criterion
Authors: Wakil Anmar Al
Published: October 2021

An abundant amount of literature has documented the limitations of traditional unconstrained mean-variance optimization and Efficient Frontier (EF) considered as an estimation-error maximization that magnifies errors in parameter estimates. Originally introduced by Michaud (1998), empirical superiority of portfolio resampling supposedly lies in the addressing of parameter uncertainty by averaging forecasts that are based on a large number of bootstrap replications. Nevertheless, averaging over resampled portfolio weights in order to obtain the unique Resampled Efficient Frontier (REF, U.S. patent number 6,003,018) has been documented as a debated statistical procedure. Alternatively, we propose a probabilistic extension of the Michaud resampling that we introduce as the Probabilistic Resampled Efficient Frontier (PREF). The originality of this work lies in addressing the information loss in the REF by proposing a geometrical three-dimensional representation of the PREF in the mean-variance-probability space. Interestingly, this geometrical representation illustrates a confidence region around the naive EF associated to higher probabilities; in particular for simulated Global-Mean-Variance portfolios. Furthermore, the confidence region becomes wider with portfolio return, as is illustrated by the dispersion of simulated Maximum-Mean portfolios.
A Novel Grid-Based Clustering Algorithm
Authors: Starczewski Artur , Scherer Magdalena M. , Książek Wojciech , Dębski Maciej , Wang Lipo
Published: October 2021

Data clustering is an important method used to discover naturally occurring structures in datasets. One of the most popular approaches is the grid-based concept of clustering algorithms. This kind of method is characterized by a fast processing time and it can also discover clusters of arbitrary shapes in datasets. These properties allow these methods to be used in many different applications. Researchers have created many versions of the clustering method using the grid-based approach. However, the key issue is the right choice of the number of grid cells. This paper proposes a novel grid-based algorithm which uses a method for an automatic determining of the number of grid cells. This method is based on the kdist
function which computes the distance between each element of a dataset and its kth nearest neighbor. Experimental results have been obtained for several different datasets and they confirm a very good performance of the newly proposed method.
Decision Making Support System for Managing Advertisers By Ad Fraud Detection
Authors: Gabryel Marcin , Scherer Magdalena M. , Sułkowski Łukasz , Damaševičius Robertas
Published: October 2021

Efficient lead management allows substantially enhancing online channel marketing programs. In the paper, we classify website traffic into human- and bot-origin ones. We use feedforward neural networks with embedding layers. Moreover, we use one-hot encoding for categorical data. The data of mouse clicks come from seven large retail stores and the data of lead classification from three financial institutions. The data are collected by a JavaScript code embedded into HTML pages. The three proposed models achieved relatively high accuracy in detecting artificially generated traffic.
Anomaly Pattern Detection in Streaming Data Based on the Transformation to Multiple Binary-Valued Data Streams
Authors: Kim Taegong , Park Cheong Hee
Published: October 2021

Anomaly pattern detection in a data stream aims to detect a time point where outliers begin to occur abnormally. Recently, a method for anomaly pattern detection has been proposed based on binary classification for outliers and statistical tests in the data stream of binary labels of normal or an outlier. It showed that an anomaly pattern can be detected accurately even when outlier detection performance is relatively low. However, since the anomaly pattern detection method is based on the binary classification for outliers, most well-known outlier detection methods, with the output of real-valued outlier scores, can not be used directly. In this paper, we propose an anomaly pattern detection method in a data stream using the transformation to multiple binary-valued data streams from real-valued outlier scores. By using three outlier detection methods, Isolation Forest(IF), Autoencoder-based outlier detection, and Local outlier factor(LOF), the proposed anomaly pattern detection method is tested using artificial and real data sets. The experimental results show that anomaly pattern detection using Isolation Forest gives the best performance.