bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of a compound vitamin B mixture in combination with GeneTime® on radiation-induced oral mucositis
Authors: Sun Hui , Zhu Xiaoshuai , Li Dan , Cheng Tao
Published: April 2019

Objective

Both compound vitamin B mixtures and GeneTime® have been used in treatment of oral inflammation. This study aimed to assess the therapeutic effects of a compound vitamin B mixture combined with GeneTime® on radiation-induced oral mucositis.

Methods

A total of 100 patients with radiation-induced oral mucositis were randomly divided into a control group (vitamin B alone; n = 50 patients) and an observation group (vitamin B plus GeneTime®, n = 50 patients). Clinical outcomes were compared between the two groups for the following 3 weeks.

Results

The observation group had a significantly greater number of grade 0–I patients and significantly fewer grade II–IV patients than the control group. Among patients in the observation group, a significantly greater number of ulcers healed within 1–2 weeks, compared with those in patients in the control group. Significantly fewer ulcers healed among patients in the observation group at 3 weeks; notably, there were fewer ulcers to heal in the observation group, compared with the control group.

Conclusions

Use of a compound vitamin B mixture combined with GeneTime® exerted obvious therapeutic effects on radiation-induced oral mucositis and markedly shortened ulcer healing time. Therefore, this strategy may be useful in clinical applications.
Toll Choice and Stochastic User Equilibrium: Ticking All the Boxes
Authors: Zill Jan C. , Camargo Pedro , Daisy Naznin Sultana , Veitch Tim
Published: April 2019

Stochastic user equilibrium is a behaviorally realistic framework for strategic demand modeling and forecasting in cities/regions where there are multiple tolled facilities, especially when it comes to patronage forecasting for existing or planned tolled facilities. However, there is currently no algorithm available in the literature or in commercial software that provides a comprehensive approach for stochastic user equilibrium assignment that addresses the generation of route choice sets for tolled roads, path overlap, and high levels of convergence. This paper presents a novel choice set generation algorithm combined with the path-size logit model and the bi-conjugate Frank-Wolfe equilibrium assignment in a comprehensive algorithm for forecasting tolled road patronage, along with the results of its application to a real-life model in Brisbane, Australia.
Pasadena’s Experience using Vehicle Miles Traveled (VMT) to Measure Transportation Impact
Authors: Dock Frederick C.
Published: April 2019

The City of Pasadena adopted new metrics for measuring transportation impact in 2015 that promote sustainable transportation and urban form. This paper describes the process by which conventional impact measures were replaced with metrics for sustainability and describes experiences with implementation of the metrics, development of companion elements, and monitoring performance. The integrated approach to planning, development review, and system management in use in Pasadena provides both a model framework for other cities and highlights the issues that can be encountered when using metrics that are less familiar to the public and decision makers.
Learning from the Budapest School women
Authors: Johnson Pauline
Published: April 2019

What can Western feminism hope to learn from women whose feminisms were originally shaped by experiences behind the ‘Iron Curtain’? In the first instance, an acute sensitivity to the importance of a politics that is responsive to needs. In its social democratic heyday, Western feminism had embraced a politics of contested need interpretation. Now, though, a neoliberal version has converted feminism into an attitudinal resource for the individual woman who is bent upon success. The takeover was made easy by the poor self-understanding of social democratic feminism. My paper will compare Agnes Heller’s theory of ‘radical needs’ and Maria Márkus’s account of the ‘politicization of needs’ and apply both to the normative clarification of endangered feminist agendas. We look to the Budapest School women for more than just a way of conceptualizing the political radicalism of modern feminism as a social movement. Women need heroes too and a reflection upon the dignified and admirable lives of Agnes Heller and Maria Márkus has much to contribute to an ongoing search for a feminist ethic of the self.
Silver triethanolamine-loaded PVB/CO films for a potential liquid bandage application
Authors: Zhou Fengzhen , Wang Wenjing , Guo Huiling
Published: April 2019

Many studies have reported that silver has excellent antibacterial properties. However, silver ions can easily react with oxygen to form Ag2O, thus leading to a color change and a reduction in its anti-microbial characteristics. In this study, silver triethanolamine- (ST) loaded PVB/CO solution was prepared as a potential candidate liquid bandage. PVB/CO/ST retained high transparency after exposure to light for 12 months, which allowed convenient inspection of the wound bed without removal of the dressing. The PVB/CO/ST film exhibited favorable properties, such as speed of drying, excellent tensile strength and elongation characteristics and water vapor transmission rate (WVTR). It was comfortable and waterproof, and therefore effective at preventing bacterial invasion, providing effective biosafety. PVB/CO/ST solution-treated wounds exhibited accelerated healing and reduced inflammation in a nude mouse mode. Our data suggested that PVB/CO/ST solution could serve as a promising liquid bandage for treatment of minor trauma.
Lipid extraction from microalgae Chlorella and Synechocystis sp. using glass microparticles as disruption enhancer
Authors: Derakhshandeh Masoud , Atici Tahir , UN Umran Tezcan
Published: April 2019

In this study, the effect of adding microparticles of glass as a cell disruption enhancer to maximize the extracted lipid from wild-type microalgae Synechocystis and Chlorella sp. has been investigated. A general factorial design approach at different levels has been implemented to evaluate the effectiveness of size and quantity of glass particles for both species. The statistical analysis of variance for the obtained results revealed the significance of the method and defined factors. The recorded extraction efficiency of lipid without addition of particles was 45.02 and 23.19% for Synechocystis and Chlorella sp., respectively. With the addition of particles, the highest recorded value for Chlorella was 34.01% which stands for 46.60% enhancement of extraction efficiency. This was achieved when 40 µm particles in 2.25 mass proportion of particle to dried biomass were used. The addition of particle did not improve the lipid extraction efficiency for the Synechocystis sp. These findings also showed that the conventional gravimetric methods may underestimate the lipid content of microalgae species.
Flow and music performance anxiety: The influence of contextual and background variables
Authors: Cohen Susanna , Bodner Ehud
Published: April 2019

Recent studies have provided empirical support for the suggestion that there is an antithetical relationship between music performance anxiety (MPA) and flow, and that this antithetical relationship may have useful clinical applications for facilitating optimal performance by both encouraging flow and reducing MPA. In order to develop music performance skills interventions that can help facilitate optimal performance, promote psychological health, and are tailored to the particular needs of individual musicians, it is important to understand the contribution of contextual (e.g., orchestral role, instrument, performance context) and background variables (e.g., gender, age, culture) to experiences of MPA and flow, and the relationships between these variables. The current study investigated the contribution of background and contextual variables to experiences of MPA and flow in a sample of 202 professional orchestral musicians in Israel. The study findings showed evidence of significantly higher flow in principal players than associate principals and tutti players. Associate principals had higher MPA than principal players, percussionists experienced higher flow and lower MPA than string players, there was a significant moderating effect of instrument on the negative association between MPA and flow, and age was significantly positively associated with flow. The implications of the findings for developing methods for facilitating optimal performing experience are discussed.
How path-creating mechanisms and structural lock-ins make societies drift from democracy to authoritarianism
Authors: Toelstede Björn
Published: April 2019

The question of how societies move between democracy and authoritarianism is of vital interest in science, as well as in the day-to-day political debate. This article contributes to this debate by exploring which mechanisms potentially encourage societies to move from democracy to authoritarianism. This article is based on the idea of traditional path dependence, tracing back to Arthur and the organizational path dependence theory by Sydow et al. Building on these theories, I examine how the so-called path-creating mechanisms can emerge and influence societies to move from democracy to authoritarianism. I develop two new concepts in this article. First, structural lock-in that describes a society deprived of its capabilities to adapt to the continuously changing environment. Second, efficient statism, describing societies which strive for higher socio-economic efficiency by embracing strong governmental forms and high conformity levels. The empirical cases presented in this article show that the path-creating mechanisms and efficient statism are regularly observable in societies. Such mechanisms put democracy at risk.
Palmetto Postmortem: Examining the Effects of the South Carolina Voter Identification Statute
Authors: Hood M. V. , Buchanan Scott E.
Published: April 2019

In 2011, South Carolina passed a government-issued photo identification (ID) statute. We examine the effects of this law on overall turnout, as well as for minority turnout in particular. A series of difference-in-difference tests are specified using individual-level population data on registrants with and without ID, comparing the 2010 (pre-implementation) and 2014 (post-implementation) election cycles. The results of our analysis indicate that the voter ID statute did dampen overall turnout. These findings comport with recent scholarship which has found evidence that voter ID laws can lower turnout rates. The size of the effect, however, is quite diminutive. We estimate that initial implementation of the South Carolina statute decreased turnout in the 2014 general election by 0.19 percent. In addition, the evidence gathered on the question of racial effects indicates that there is no discernible racial impact from the state’s voter ID law.
Collaborative Partnership: Opening Doors Between Schools and Universities
Authors: Farah Yara N.
Published: April 2019

Although K-12 schools and universities are two separate and distinct systems, fundamentally both have the same broad goal: the education of students. This leads one to ponder, “How can these two entities work together to promote, foster, and support this goal?” In this article, I share and discuss the key elements for building a successful school–university collaborative partnership. A type of partnership that includes ongoing commitment founded on mutually beneficial goals, trust, equitable decision making, and communication. A partnership that produces high-quality research, improves educational practices in schools, and contributes to the field.
Implementing Innovation in Different Service Delivery Models
Authors: Feldman-Adams Deborah , Bird Megan , Dwosh Janice , Warner ElizaBeth
Published: April 2019

This article reviews recent efforts to implement the William & Mary English Language Arts (ELA) curriculum within the Paradise Valley Unified School District gifted programs. The programs include self-contained gifted, as well as content replacement programs in Title 1 and Non-Title 1 schools. Each delivery model modified the constructs of the curriculum to meet the unique needs of the students serviced. All results indicated successful academic progress and student growth.
A Highly Successful School–University Partnership
Authors: Cross Tracy L.
Published: April 2019

This column introduces a collaborative partnership between the Center for Gifted Education at William & Mary and the Paradise Valley School District in Phoenix, Arizona. It describes its history and the leadership of the project.
Research Falling Out of Colorful Pages Onto Paper: Collage Inquiry
Authors: Lahman Maria K. E. , Taylor Christina M. , Beddes Lindsay A. , Blount Ivan D. , Bontempo Kimberli A. , Coon Joshua D. , Fernandez Cyrus , Motter Barry
Published: April 2019

As part of an advanced doctoral course on representing qualitative research, the authors used collage to represent either who they were as researcher or the research they were conducting. The authors, comprised of the course professor and seven doctoral students, read about collage as inquiry and research representation and then participated reflexively in a course lecture on the background of collage, a collage creation activity, a gallery walk, written and oral reflection on each other’s collages, a research poster presentation at a campus research event, and a final reflection of the entire process. As the process unfolded the authors represented the experience in the form of a collective collage poem, and a methodological and pedagogical article. Elements of this article include a review of collage as an art and research inquiry form, an overview of the pedagogical experiences, and the authors’ experiences shared in the form of brief vignettes and collage images.
Can a Social Norms Appeal Reduce Indoor Tanning? Preliminary Findings From a Tailored Messaging Intervention
Authors: Carcioppolo Nick , Peng Wei , Lun Di , Occa Aurora
Published: April 2019

Perceived social norms are routinely observed as positive predictors of indoor tanning. Past research has suggested that messaging interventions target normative perceptions to reduce indoor tanning behavior. Despite this call, little empirical research has investigated the utility of taking a social norms approach in behavioral interventions. The present study addresses this gap by conducting a quasi-experiment ( N = 206) assessing the effect of an intervention message correcting normative misperceptions on indoor tanning intentions at different levels of tanning frequency. Results suggest that tailored normative intervention messages can successfully reduce tanning intentions among high-frequency tanners, those who scored at the 75th and 90th percentile of tanning frequency ( f2 for interaction = .015). These results provide preliminary empirical evidence to support previous theorizing on the efficacy of social norms interventions among high-frequency indoor tanners.
Ranking Hospitality and Tourism Journals
Authors: Law Rob , Chan Irene Cheng Chu , Zhao Xinyuan (Roy)
Published: April 2019

Publications and reports on ranking journals are commonly found in various disciplines, including hospitality and tourism. They rank the journals on a list based on subjective judgment of experts and/or objective third-party indicators. The ranking of a journal represents its quality and prestige in the field. However, there exists no commonly agreed rankings of hospitality and tourism journals due to the different methods adopted. The current commentary critiques the relevance and accuracy of such rankings by revealing the potential methodological biases and limited implications in knowledge development.
Heart transplant secondary to cobalt toxicity after hip arthroplasty revision
Authors: Sanz Pérez Marta I , Rico Villoras Alberto M , Moreno Velasco Aurelio , Bartolomé García Sergio , Campo Loarte Jesús
Published: April 2019

Introduction:

Cobalt toxicity in patients with hip arthroplasty is a rare complication, but it should be considered in those patients who, after a ceramic fracture, were implanted with a metal-on-polyethylene prosthesis. The complete removal of ceramic particles during revision surgery can be complicated. If the bearing surface is replaced with a metal-on-polyethylene prosthesis, these residual ceramic particles may wear down the chrome-cobalt head, producing localised metallosis. This can trigger blood metal ion levels to rise, causing systemic toxicity. Visual and auditory alterations, cognitive deterioration, hypothyroidism, neuropathy, cardiomyopathy, anorexia, fatigue, diabetes, polycythemia, and respiratory and cutaneous symptoms are some of the clinical manifestations of prosthetic cobaltism.

Case description:

A young patient presented with multiorgan failure secondary to cobalt toxicity after a ceramic fracture and revision with a metal-on-polyethylene prosthesis; his serum cobalt and chromium levels were 652 μg/L and 270 μg/L, respectively. The patient needed a heart transplant after presenting with cobalt-induced cardiogenic shock.

Conclusions:

In a patient with a ceramic fracture who is subjected to revision surgery with a metal-on-polyethylene bearing, it is necessary to rule out the possibility of cobalt intoxication. Serum cobalt levels > 20 μg/L are inadmissible; in these cases, surgical treatment should be considered in the short term. A wide synovectomy and replacement of components should be performed with hard friction options, preferably with a ceramic-on-ceramic prosthesis.
Investigating the Feasibility of Brief Compassion Focused Therapy in Individuals in Treatment for Opioid Use Disorder
Authors: Carlyle Molly , Rockliff Helen , Edwards Rachel , Ene Crina , Karl Anke , Marsh Beth , Hartley Lucie , Morgan Celia JA
Published: April 2019

Opioid use disorder (OUD) is reaching epidemic proportions worldwide, and is notoriously difficult to treat. Compassion focused therapy (CFT) has emerged as therapeutic tool for treating individuals exhibiting high levels of self-criticism and low self-esteem, both of which are common in OUD. Until now, however, there had been no research investigating this therapy in patients with OUD. Before running a premature clinical trial, it is important to fully assess the feasibility and acceptability of this treatment in this group of individuals. We aimed to assess the feasibility of CFT treatment in individuals with OUD in a short group intervention, which was co-created by the research team, service users and a local drugs service. The intervention involved three 2-hour sessions held over 3 weeks, where participants engaged in compassion-orientated psychoeducation and self-compassionate exercises. Individuals were randomly assigned to either the CFT group (n = 15), the active control (relaxation) group (n = 12) or the waitlist control group (n = 11). Of 103 individuals approached, 45% attended a baseline visit suggesting the treatment was acceptable to this group. A relatively low attrition rate across the 3 groups was found for CFT (21.1%), with no difference in drop-out between the groups. Qualitative analysis of interviews with participants identified a desire for more sessions. Compassion focused therapy was thus feasible and well-tolerated in those with OUD, and a further trial to evaluate any clinical differences may be warranted.
Effective Models Urgently Needed to Improve Physical Care for People With Serious Mental Illnesses
Authors: Chang Evelyn T , Vinzon Merlyn , Cohen Amy N , Young Alexander S
Published: April 2019

People with serious mental illness have substantially worse health outcomes than people without mental illness. These patients use primary care less often and fail to receive needed preventive and chronic care. While a variety of care models have been implemented with the goal of improving care for these patients, few have been found to be effective. Young et al describes a specialty patient-centered medical home for patients with serious mental illness. In this model, the primary care provider manages the medical and mental health conditions of patients with stable psychiatric symptoms with assistance from a registered nurse and a consulting psychiatrist. The goal of this integrated model is to engage patients in preventive care by building a relationship with them in primary care and understanding both their medical and psychiatric needs. While this model may improve care and increase patient satisfaction, implementing this type of model may be challenging.
The Use of Biologic Therapy in the Treatment of Acrodermatitis Continua of Hallopeau: A Review
Authors: Maliyar Khalad , Crowley Erika L. , Rodriguez-Bolanos Fabian , O’Toole Ashley , Gooderham Melinda J.
Published: April 2019

Acrodermatitis continua of Hallopeau is a rare subtype of pustular psoriasis that presents as a sterile, pustular eruption commonly in the finger tips and toes. This disease inflicts both the skin and nail bed, and causes severe disfigurement of the distal phalanges. Because it is a variant of pustular psoriasis, acrodermatitis continua of Hallopeau is commonly managed with antipsoriatic medications. Common approaches to treatment include topical therapy (corticosteroids, vitamin D analogs, and calcineurin inhibitors), systemic therapy, and in more severe cases, biologic therapy. This review will discuss how acrodermatitis continua of Hallopeau is diagnosed and how it is managed, with a particular emphasis on the use of biologics.
Effect of microhole-textures filled with graphite on tribological properties of WC/TiC/Co carbide tools
Authors: Song Wenlong , Wang Shoujun , Xia Zixiang , Zhang Xuan
Published: April 2019

To expand the industrial application of cemented carbide, micro-EDM was utilized to machine microhole-textures on the carbide surface; graphite powder was burnished into the textured microholes. The tribological properties of the microhole-textured tool combined with graphite were investigated and compared with the conventional one by carrying out reciprocating sliding friction tests and dry machining tests. Results exhibited that the microhole-textured tool combined with graphite possessed a much lower friction coefficient than that of the conventional one in sliding tests. The cutting forces, average friction coefficient at the tool–chip interface, and rake face wear of the textured tool were reduced, and the workpiece surface quality was also slightly improved. The worn regions of carbide specimen were examined and studied, and the possible effect mechanisms for the enhancement of friction and wear properties mainly consisted of the formation of uneven graphite film by friction extrusion, reduction of actual contact length, entrapment of wear debris and supply of graphite lubricant.
Evaluation of key factors for service experience: A comparison of tourism factories and international tourism hotels
Authors: Hsieh Yen-Hao , Chuang I-Chun
Published: April 2019

When building successful service experience, service providers have to consider multiple factors from a multi-element standpoint. This study aims to establish a new conceptual model for key factors affecting service experience and determine the influential key factors using a multi-perspective and multi-criteria methods. This study uses an analytic network process (ANP) to calculate the degree of influence exerted by the criteria and factors of the service experience and conducts in-depth interviews to validate the results of the ANP, improving the reliability of the results of the study and increasing its practical reference value. Results from tourism factories and international tourist hotels find five main criteria that affected service experience: employee, customer, service environment, information technology, and knowledge creation. The results reveal that employee and service environment are the most important criteria. Therefore, tourism factories and international tourist hotels must invest resources in training and managing employees to equip them with specialized knowledge needed to deliver high-quality service experience. Tourism factories and international tourist hotels also need to pay attention to service environments, and by building an environmental ambience, they allow customers to receive an aesthetically pleasing and comfortable service experience. Future researchers can extend this study’s architecture and results, incorporate other important criteria and factors, and consider the interdependent relations between multiple key factors to further improve the key factors affecting service experience.
Test anxiety in physical education: The predictive role of gender, age, and implicit theories of athletic ability
Authors: Danthony Sarah , Mascret Nicolas , Cury François
Published: April 2019

Test anxiety is experienced by a substantial number of students in many school subjects, including physical education, and it may be deleterious for their school performance and their well-being. The aim of our study was to explore through multiple regression and mediation analyses the relationships between test anxiety in physical education, implicit theories, gender, and age. Five hundred and twenty-six French students ( Mage = 15.82, SD = 1.19) voluntarily participated in the study. The results mainly highlighted the following: Gender was a significant predictor of all the components of physical education test anxiety, evidencing that girls scored higher than boys on the four negative components (worry, self-focus, bodily symptoms, somatic tension), and lower on the positive component (perceived control). Age negatively predicted the self-focus component only. Entity theory was a significant predictor of the five components of test anxiety, whereas incremental theory only positively predicted perceived control. Entity theory partially mediated the relationships between gender and perceived control. A better understanding by physical education teachers of the characteristics of their students (e.g. gender differences, age, implicit theories of athletic ability) may contribute to decreasing test anxiety in physical education.
Aerodynamic performance and analysis of a hovering micro-scale shrouded rotor in confined environment
Authors: Han Han , Xiang Changle , Xu Bin , Yu Yong
Published: April 2019

The aerodynamic characteristics of open rotor hovering in confined environment are extensively studied, but few papers focus on shrouded rotor. In order to study aerodynamic performance and flowfield characteristics of micro-scale shrouded rotor hovering in confined environment, experimental measurements and computational fluid dynamic simulations are conducted in this article. Three cases of confined planes including ground, ceiling, and wall close to shrouded rotor are studied successively. Another case of no confined planes around shrouded rotor is also researched. Results show that both ground and ceiling improve the aerodynamic performance of shrouded rotor at distance below 1.5 rotor radii with the enhanced figure of merit, while wall plane influences flight stability because of the unbalanced moment. The experimental data reveal that the performance of shrouded rotor in-ground effect is more sensitive than that of shrouded rotor in-ceiling effect. However, for in-ground effect or in-ceiling effect, the performance of shrouded rotor is more sensitive than that of open rotor. Flowfield analysis by computational fluid dynamic shows the confined planes block airflow around shrouded rotor. Tip flow leakage and flow separation occur near shroud lip when shrouded rotor is hovering considerably close to ground or ceiling. Turbulent vortices and fluctuating velocities affect the flight stability of shrouded rotor.
Accuracy design of the Stewart manipulator of the Five-hundred-meter Aperture Spherical radio Telescope
Authors: Yao Rui , Fu Changhai , Sun Caihong , Zhu Wenbai
Published: April 2019

A Stewart manipulator is used in the Five-hundred-meter Aperture Spherical radio Telescope to ensure the position and orientation accuracy of the feed receivers. Due to the weight limit, the feed cabin has a low stiffness, which highly affects the control accuracy of the Stewart manipulator based on the control conditions. The main purpose of this article is to present an effective accuracy design method of the Stewart manipulator of the Five-hundred-meter Aperture Spherical radio Telescope. First, error modeling of the Stewart manipulator with the structural deformation is set up, which can indicate the influence on the control error caused by the structural deformation in real-time control. Second, by analyzing the accuracy factors of the Stewart manipulator, the end-effector error limit caused by the structural deformation is obtained. Third, an error distribution method based on the maximum coefficient method is proposed, which guides the structural design of the feed cabin. Fourth, a semi-physical simulation model of the feed cabin is set up to simulate the control accuracy of the feed cabin, and the experiment results show that the control error of the feed cabin is within root mean square 4.8 mm. Finally, the feed cabin is effectively used in the Five-hundred-meter Aperture Spherical radio Telescope within its root mean square 10-mm accuracy requirement.
Outcome after intravenous thrombolysis in patients with acute lacunar stroke: An observational study based on SITS international registry and a meta-analysis
Authors: Matusevicius Marius , Paciaroni Maurizio , Caso Valeria , Bottai Matteo , Khurana Dheeraj , de Bastos Mario , Martins Sheila CO , Krespi Yakup , Cooray Charith , Toni Danilo , Ahmed Niaz
Published: April 2019

Background

Intravenous thrombolysis (IVT) for lacunar stroke (LS) is debated, as the underlying pathophysiological mechanism may not be thrombogenic.

Aims

To investigate outcomes after IVT in LS in the SITS International Stroke Thrombolysis Register and perform a meta-analysis.

Methods

LS was identified by both baseline NIHSS-subscores and discharge ICD-10 codes, and contrasted by IVT to non-IVT treated. IVT patients were predominantly from Europe, non-IVT patients predominantly from South America and Asia. Outcome measurements were functional independence (modified Rankin Scale [mRS] score ≤2), excellent outcome (mRS ≤ 1), and mortality at three months. Matched-control comparisons of symptomatic intracerebral hemorrhage (SICH) between IVT-treated LS and IVT-treated non-LS patients were performed. Additionally, we performed a meta-analysis.

Results

Median age for IVT-treated LS patients ( n = 4610) was 66 years vs. 64 years and NIHSS score was 6 vs. 3, compared to non-IVT-treated LS ( n = 1221). Univariate outcomes did not differ; however, IVT-treated LS patients had higher adjusted odds ratios (aOR) for functional independence (aOR = 1.65, 95% CI = 1.28–2.13) but similar mortality at three months (aOR = 0.57, 0.29–1.13) than non-IVT-LS. Propensity-score matched analysis showed that IVT-treated LS patients had a 7.1% higher chance of functional independency than non-IVT LS patients ( p < 0.001). IVT-treated LS patients had lower odds for SICH (aOR = 0.33, 0.19–0.58 per SITS, aOR = 0.40, 0.27–0.57 per ECASS-2) than matched non-LS controls, which was mirrored in the meta-analysis.

Conclusions

Our adjusted results show that IVT treatment in LS patients was associated with better functional outcome than non-IVT-treated LS and less SICH than IVT-treated non-LS patients.
Chronic pain: Sources framing of post-traumatic stress in The New York Times
Authors: Barnett Barbara , Lee Tien T
Published: April 2019

Post-traumatic stress (PTS) is a common reaction after witnessing a violent event, and individuals who have experienced trauma may relive the event, avoid people or situations that remind them of the trauma, or experience negative thoughts and hyperarousal. When symptoms persist, an individual may receive a medical diagnosis of Post-Traumatic Stress Disorder (PTSD). While nearly eight million Americans, including combat veterans, have PTSD in a given year, few studies have explored how the condition is represented in the mass media. This content analysis examines sources’ characterization of PTSD in New York Times articles. Results show that news stories framed PTSD as a long-term problem, with little chance for recovery, a frame that could negatively affect public policy decisions.
Dealing with complexity in type 2 diabetes
Authors: Basudev Neel
Published: April 2019

The management of people with type 2 diabetes (or type 2 diabetes mellitus) can be complex and sits largely within the portfolio of primary care. Unfortunately, despite an ever-increasing therapeutic armoury, many people with type 2 diabetes fail to achieve optimal control of their blood glucose and other metabolic indices, putting them at higher risk of diabetes-related complications. The situation has sadly changed little over recent years. People with type 2 diabetes often have other long-term health concerns that need to be recognised and addressed alongside more traditional parameters such as blood glucose and blood pressure. In this article, we will consider the recognition and management of two of the more common conditions that co-exist in people with type 2 diabetes: Diabetes distress and renal disease. Although there is undoubtedly some overlap with type 1 diabetes, the discussion in this article solely relates to the management of type 2 diabetes.
Strengthening the School Nurse Voice With Data Governance
Authors: Maughan Erin D. , Reiner Kathy L.
Published: April 2019

This interview provides a practical example of how a school district manages their data. It is a practical example of how to apply the principles found in the article on data governance, which is part of the “data and school nursing” articles series being published in NASN School Nurse during the 2018-2019 school year.
Management of anti-thrombotic therapy in patients with recent percutaneous coronary intervention and acute dengue infection: A case series
Authors: Aditya Wishnu , Yap Jonathan , Chlebicki Piotr , Chan Charles Wah Hak , Tan Jack Wei Chieh
Published: April 2019

There is currently little data regarding the ideal management for a patient who has undergone recent percutaneous coronary intervention (PCI) and subsequently develops dengue fever. Patients with recent PCI are at high risk of stent thrombosis with cessation of dual anti-platelet therapy. On the other hand, patients with dengue viral infection are at high risk of bleeding. Managing patients with recent PCI and dengue involves the delicate balancing of the risk of thrombosis and bleeding. Careful consideration of the timing of coronary intervention and the severity of the dengue infection is required. We describe the management of the anti-thrombotic therapy in three different patients with dengue infection and recent PCI and discuss our approach to managing such patients.
Risk factors for cognitive impairment in older people with diabetes: a community-based study
Authors: Xiu Shuangling , Liao Qiuju , Sun Lina , Chan Piu
Published: April 2019

Aim:

The aim of this study was to investigate the risk factors for cognitive impairment in older people with diabetes.

Methods:

This cross-sectional study included 2626 community-dwelling participants with diabetes aged ⩾55 years, living in Beijing, China. The participants were screened for risk factors, including smoking, obesity, hypertension, stroke, coronary heart disease, dyslipidemia, depression, apolipoprotein E (APOE) genotype, and low physical activity. Cognitive function was assessed with the scholarship-adjusted Mini-Mental State Examination (MMSE): MMSE ⩽17 for iliterate participants; MMSE ⩽20 for primary school graduates (⩾6 years of education); and MMSE ⩽24 for junior school graduates or above (⩾9 years of education).

Results:

The prevalence of cognitive impairment in older people with diabetes was 9.90%. Multiple logistic regression analysis demonstrated that stroke [odds ratio (OR) = 1.71, 95% confidence interval (CI) = 1.20–2.43], less than 0.5 h exercise per day (OR = 1.89, 95% CI = 1.37–2.61), and depression (OR = 1.64, 95% CI = 1.06–2.54), but not smoking, obesity, hypertension, dyslipidemia, and coronary heart disease, were independent risks for cognitive impairment in older people with diabetes. In addition, being married (OR = 0.66, 95% CI = 0.47–0.93) and urban living (OR = 0.33, 95% CI = 0.22–0.48) could decrease the risk of cognitive impairment.

Conclusions:

Stroke, depression, and less than 0.5 h exercise per day were independent risks for cognitive impairment in older people with diabetes, whereas being married and urban living were protective.
Effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock
Authors: Wang Fengzhi , Zhang Mancui , Wang Xiujuan , Zhong Xiaopeng , Ding Po
Published: April 2019

The effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock remained unknown. In this study, we included 124 cases of severe septic shock patients in our hospital. The patients were randomly divided into control group (treated with dopamine) and experimental group (treated with dopamine plus norepinephrine), while the hemodynamic index (heart rate (HR)), blood vessel elasticity index, heart pump function, and inflammatory factor index were recorded. After 12 h of treatment, both groups showed decreased HR, increased levels of cardiac index (CI), mean arterial pressure (MAP), central venous pressure (CVP), peripheral vascular resistance index (PVRI), and vascular elasticity ( P < 0.05). To date, lower HR, higher levels of CI, MAP, CVP, and PVRI were observed in the experimental group ( P < 0.05). Furthermore, the vascular elastic coefficient, stiffness index, arterial compliance, and the precursors of plasma amino-terminal brain natriuretic peptide were also significantly higher in the experimental group than those in the control group ( P < 0.05). However, inflammatory cell tumor necrosis factor alpha factor test group (TNF alpha), interleukin-1 (IL-1), and interleukin-6 (IL-6) concentrations were significantly lower than the control group ( P < 0.05), compared to experimental group ( P < 0.05). This research indicates that phenylephrine could significantly improve hemodynamics in patients with severe septic shock, by maintaining blood vessel elasticity, improving heart pump function, and reducing the inflammatory factors’ activities, and this method could be used as a line of vascular tension of the medications used in patients with septic shock.
Frameworks and Models for Disseminating Curated Research Outcomes to the Public
Authors: Clifton-Ross Jaime , Dale Ann , Newell Robert
Published: April 2019

In our post-truth society, mobilizing “facts” and “evidence” has never been more important. We live in an age that is paradoxically information rich due to the proliferation of Internet Communication Technologies (ICTs) and information poor due to the spread of misinformation. Academic research outcomes are traditionally disseminated via peer-reviewed publications, conference presentations, and in the classroom; however, this research is not often effectively communicated to both decision makers and the general public(s). There is no perfect way of disseminating research outcomes; however, there are lessons to be learned from curatorial and communication frameworks developed in museums as these institutions have a long history educating and engaging the public. This article explores the new concept of “research curation,” or rather the enhanced dissemination of curated research outcomes to reach diverse audiences. Closing the “gap” between academia and the public is essential for increasing civic literacy around issues that threaten sustainability. By adapting curatorial and communication methods developed in museums along with ICT models, the practice of “research curation” can be an effective framework for improved dissemination of academic knowledge.
Acute renal failure in systemic sclerosis revealing Goodpasture syndrome: “All that glitters is not scleroderma renal crisis”
Authors: Felten Renaud , Nespola Benoît , Chatelus Emmanuel , Arnaud Laurent , Gottenberg Jacques-Eric , Canuet Matthieu , Prinz Eric , Goetz Joëlle , Sibilia Jean
Published: April 2019

The most common cause of acute renal failure in systemic sclerosis patients is scleroderma renal crisis but other etiologies have to be considered such as another autoimmune disease. We report the case of a 60-year-old male admitted to our hospital with a renal failure. His medical history included a diagnosis of systemic sclerosis 6 months ago. Antinuclear antibodies were positive at a titer of 1:1280 with positive anti-Scl-70 and anti-myeloperoxidase (34 U/mL) antibodies. Scleroderma renal crisis was suspected. However, antineutrophil cytoplasmic antibody–associated vasculitis could not be excluded and a renal biopsy was performed. Histopathology revealed crescentic glomerulonephritis and rupture of Bowman’s capsule. Anti-glomerular basement membrane antibodies were detected in serum and the diagnosis of Goodpasture syndrome was confirmed by kidney’s immunofluorescence analysis showing typical deposits. Only three other cases of systemic sclerosis associated with Goodpasture syndrome have been reported in the literature. Also, rapidly progressive glomerulonephritis with positivity of both antineutrophil cytoplasmic antibody and anti-glomerular basement membrane antibodies has been described. Several studies have suggested that antineutrophil cytoplasmic antibody positivity occurs first leading to damages of the glomerular basement membrane, to the release of alpha-3 NC1 antigen, and ultimately to anti-glomerular basement membrane antibody production. Although rare, antineutrophil cytoplasmic antibody–associated vasculitis and Goodpasture syndrome should be searched for in systemic sclerosis patients with acute renal failure.
Collective irrigation, the state and social relations in the Eastern Pyrenees of France
Authors: Delay Etienne , Linton James
Published: April 2019

In this article, we consider the social effects of a large dam in the Eastern Pyrenees region of France. In 1976, the French state constructed a dam near the town of Vinça on the Têt River, altering the hydrological conditions that had co-produced a complex system of hydro-social relations evolved since the Middle Ages. We argue that through altering the relative proximity of dependencies between farmers and between farmers and the state, the dam has had the effect of transferring expertise and social power from local to central authority. However, this shift is made difficult by the evolution of local farmers associations to take advantage of the new hydrological circumstances produced by the dam. The production of hydrological certainty assured by the dam has changed the raison d’etre for these associations (known as Association Syndicale Autorisée), providing them with new opportunities such as in the development of pressurized drip irrigation. In these circumstances, the relations between the Association Syndicale Autorisée and the state produce a hybridized authority over water, neither quite centralized nor local but combining both. We draw from Bookchin’s elaboration of ‘post-scarcity anarchism’ as well as Bouba-Olga and Grossetti’s concept of proximities to describe the pitfalls and the promises of pressurized irrigation in the region, made possible by the dam.
Outcomes Following Interposition Arthroplasty of the First Metatarsophalangeal Joint for the Treatment of Hallux Rigidus: A Systematic Review
Authors: Emmons Brendan R. , Carreira Dominic S.
Published: April 2019

Background:

Interposition arthroplasty of the first MTP joint has recently experienced renewed interest as a treatment for hallux rigidus. The purpose of this study was to systematically review the rapidly expanding literature on PRO following interposition arthroplasty of the first MTP joint.

Methods:

PubMed Central, Embase, and the Cochrane Central Register for Controlled Trials (CENTRAL) were searched. Inclusion criteria included length of time to follow-up, number of patients, outcome measure, and use of allogeneic or autogenous soft tissue or a synthetic matrix as interposition.

Results:

20 studies were included in the review, comprising 498 patients and 539 feet with mean time to follow-up of 4.5 years. The most common substance used for interposition in the included studies was autogenous first MTPJ capsular tissue, a technique reported on in 12 (60.0%) of the included articles. In studies reporting preoperative and postoperative outcomes by way of a standardized outcome scoring system, mean group improvements exceed minimal clinically important differences in the majority of studies. Eighty-five percent of the studies included in this review were of Level IV quality evidence, and of this subset of studies, 70.6% were of a retrospective nature. Progression to further surgery was observed in 3.8% of toes. The most common complication reported was transfer metatarsalgia of 1 or more lesser toes, observed in up to 57.9% of patients in one study.

Conclusion:

Interposition arthroplasty appears to be a viable option for the treatment of moderate to severe hallux rigidus in patients looking to salvage motion through the first metatarsophalangeal joint. A wide array of autogenous, allogeneic, and synthetic implant materials have surfaced in recent years, but long-term follow-up and prospective, comparative study designs with low risk of bias are limited.

Level of Evidence:

Level IV, systematic review of Level III-IV studies
Direct transretinal removal of subfoveal perfluorocarbon liquid combined with internal limiting membrane peeling
Authors: Erden Burak , Erdenöz Serkan , Çakır Akın , Bölükbaşı Selim , Elçioğlu Mustafa
Published: April 2019

A 65-year-old woman was referred to our institution with a 5-day history of visual impairment in her right eye and macula-off retinal detachment. A successful 23 G pars plana vitrectomy was performed with a 1000 cs silicone oil injection, and the silicone oil tamponade was extracted 2 months later. During the fundoscopic and optical coherence tomography examinations, three subfoveal perfluorocarbon liquid bubbles were detected, and her best corrected visual acuity was limited to 20/400. Brilliant blue staining was used for the internal limiting membrane peeling, and the direct transretinal aspiration of the perfluorocarbon liquid bubbles was performed with a 23 G silicone-tip Flute cannula. This patient’s best corrected visual acuity increased to 20/200 at the 1 month follow-up and then to 20/100 at the 1-year follow-up.
Project Managers’ Competences in Managing Project Closing
Authors: Wen Qi , Qiang Maoshan
Published: April 2019

Closing is a strategic but frequently overlooked project phase, in which project managers play pivotal roles as project team leaders. This study pinpoints project managers’ competences underpinning the effective management of project closing, defined as project managers’ closing competence (PMCC). A conceptual model of how PMCC contributes to project closing performance (PCP) was developed from related literature. Based on questionnaire data from 163 project management practitioners, partial least squares structural equation modeling (PLS-SEM) was employed to test the model and identify the most influential PMCC dimensions and indicators. The results reveal four PMCC dimensions (i.e., knowledge and skills, external stakeholder management, leadership in project team, and organization-level ability) significantly affecting PCP. The PLS-SEM results also quantify the relative importance of the indicators in each PMCC dimension. Comparing the findings with recent literature, we found that risk awareness, closing contract relationships, helping staff with career planning, participating in project closing decisions, and obtaining support from other departments are crucial aspects of PMCC that deserve more attention in research and practice. The findings heed the call for identifying competences according to project tasks, and operationalize PMCC and PCP into detailed indicators. The proposed PMCC framework also provides practical implications for project manager evaluation and selection.