bluuebunny/crossref_metadata_2025 huggingface dataset:
Nuevos enfoques, dogmas, herejías y ajustes de cuentas. Un mapa aproximado del pensamiento comunista español en el exilio
Authors: Andrade Blanco Juan
Published: June 2019

Este artículo analiza varias líneas fundamentales del pensamiento político de los comunistas españoles durante el exilio de 1939 a 1975. Lo hace a partir de la consideración de las grandes obras publicadas, pero también de ensayos más livianos, de debates mantenidos en encuentros y órganos de dirección y de los mítines o discursos luego publicados en libros, revistas o folletos. En él se presta especial atención a las reflexiones teóricas acerca del Estado, las posibilidades de trasformación social y la tradición ideológica y cultural propia. También a los análisis históricos sobre el movimiento comunista, el PCE y su participación en la Guerra civil. De igual modo se atiende, muy especialmente, a los análisis acerca de la evolución del Franquismo y las posibles estrategias de transición a la democracia. La atención se centra en lo producido por aquellos militantes y dirigentes comunistas con mayores veleidades intelectuales y por aquellos intelectuales comunistas que tuvieron un mayor compromiso orgánico. Todo ello es abordado desde la perspectiva de la nueva historia del pensamiento político y la historia intelectual que ponen el acento en cómo estas se van tejiendo, más allá de su autoría individual, al calor de los conflictos sociales, políticos y culturales de una época.
Pervivencia de las fosas comunes de la guerra civil española en el siglo XXI. Evidencia cultural, particularidad académica
Authors: Solé Queralt
Published: June 2019

En el presente artículo se desarrolla una aproximación a las diferentes formas de producción cultural e histórica que se han realizado en España en torno a las fosas comunes de la guerra civil española en el siglo xxi. Se realiza una breve descripción de las diversas producciones culturales aparecidas en relación con este tema y se expone la incidencia que han tenido las exhumaciones de fosas en los estudios académicos, sobre todo en el ámbito de la historia. Se numeran las universidades e investigadores que han trabajado las fosas comunes como unidad de análisis y se reflexiona respecto a la contribución al conocimiento que los datos históricos de las exhumaciones pueden aportar para la comprensión de los procesos represivos franquistas.
Examination of Maternal Assets and Breast Milk Expression
Authors: Bai Yeon K. , M. Dinour Lauren
Published: June 2019

The proportion of mothers in the workforce has increased over the past 40 years. Examination of factors associated with a working/student mother’s milk expression is needed to provide effective lactation support. The purpose of this study was to examine the role of maternal assets in the relationships between the theory constructs, intention, and behavior of breast milk expression. Using a cross-sectional design framed under the theory of planned behavior, all female personnel associated with a higher education institute in northern New Jersey were invited to participate in the online survey, Milk Expression on Campus. Attitude toward breast milk expression, subjective norm, perceived behavioral control, intention, and behavior of breast milk expression on campus as well as maternal assets such as income, education, living status, and campus role were measured. Maternal assets had no moderation role but showed a significant and meaningful mediation effect on the relationship between perceived behavioral control and the intention to express breast milk on campus, with effect size R2=3.59%, 95% CI (-.1061, -.0047). There was no mediation effect of the asset on the relationship between intention and the behavior of breast milk expression, 95% CI (-.0984, .0232). Future breastfeeding support and promotion may direct its attention to provide systematic social and clinical support to enhance working/student maternal assets, e.g. family education, access to lactation services, or peer-based support programs, thereby helping mothers achieve their breastfeeding goals.
Causative Factors behind an Efficacious Teacher: Evaluating Teacher Efficacy
Authors: Batool Sadia , Shah Syed Mubarak Abbas
Published: June 2019

In the third world school dropout rates are the highest, which is largely attributable to a dearth of efficacious teachers. The present research is an analysis of the teacher efficacy based on the teaching milieu. The Ohio State Teacher Efficacy Scale was used for data collection. Probability sampling design was used to select 171 secondary school teachers. As per the results, subject specialization affects teacher efficacy the most whereas, institution type influences teacher efficacy the least. The less experienced teachers have a greater self-efficacy than the experienced teachers, teachers teaching uncrowded classes are more efficacious than those teaching crowded classes.
The glucose-lowering therapy structure in special groups of type 2 diabetes mellitus patients based on data from the Moscow region register
Authors: Misnikova Inna V. , Kovaleva Yulia A. , Isakov Mikhail А. , Dreval Alexander V.
Published: June 2019

BACKGROUND: Data of real clinical practice in diabetes mellitus (DM) register allow to evaluate features and trends in structure of glucose-lowering therapy (GLT).
AIM: Тo analyze of structure of GLT received by patients with type 2 diabetes mellitus (T2DM) in Moscow region for 2018 and to evaluate its dynamics over 15 years.
METHODS: Analysis of GLT structure was carried out on basis of data from register of patients with DM in Moscow region, which is part of National register of diabetes mellitus in Russian Federation. In March 2018 it contained data on 211,792 T2DM patients of Moscow region. Structure of GLT administration was evaluated according T2DM duration, patients age and presence of cardiovascular diseases (CVD). Dynamics of GLT is analyzed from 2004 to 2018 yrs.
RESULTS: In 2018 non-insulin glucose-lowering drugs (NIGD) prescription prevailed (78.3%), insulin therapy was prescribed in 18.5% of patients, 3.2% of patients did not receive drug therapy. Most commonly prescribed NIGD were metformin (69.3%) and sulfonylurea (51.3%). Older patients more often than younger did not use GLT at all and less frequently received insulin therapy and iDPP-4. Insulin therapy was prescribed twice as often in patients with CVD compared with patients without CVD (29.6% and 15.5%). NIGD monotherapy has been less commonly used in patients with CVD (67.3% and 81.2%). Glucagon-like peptide-1 receptor agonists (GLP-1 RA) were prescribed to patients with CVD GLP-1 RA in 0.1% of cases, without CVD in 0.3% of cases, and sodium-glucose cotransporter 2 (SGLT2) inhibitors in 1.1% and 0.6%. correspondently.
CONCLUSION: Metformin was most commonly prescribed drug in GLT structure for T2DM patients in the Moscow region in 2018 yr. Percentage of new drugs in the structure of GLT increased mainly due to iDPP-4, and secondly due to SGLT2 inhibitors. New classes of GLT were more often prescribed to patients of younger age, with diabetes duration up to 10 years, overweight or obese. Administration of NIGD with proven cardiovascular protection in presence of CVD is almost two times less than for those without CVD.
A clinical case of neonatal diabetes caused by INS gene mutation
Authors: Atanesyan Rosa A. , Uglova Tatyana A. , Vdovina Tatyana M. , Klimov Leonid Ya. , Kostanova Marina U. , Kuryaninova Victoriya A. , Stoyan Marina V. , Alaverdyan Lilit S. , Dolbnya Svetlana V.
Published: June 2019

Neonatal diabetes mellitus (NDM) is a severe endocrine pathology diagnosed in children during the first months of life. It comprises rare (1:300 0001:400 000 newborns) metabolic disorders with postnatal pancreatic -cell dysfunction, manifested by hyperglycaemia and hypoinsulinaemia. It is currently established that molecular genetic diagnosis of neonatal diabetes forms can influence treatment and prognosis. Interestingly, most identified mutations in the insulin gene are not inherited, but are sporadic. There is evidence that, in addition to heterozygous INS mutations, NDM can be caused by homozygous or compound-heterozygous mutations.
The present article presents the clinical case of a girl with NDM associated with an INS gene mutation. INS gene mutations cause permanent diabetes and require children to undergo genetic examination, especially patients with type 1 diabetes in the absence of antibodies.
Currently, there are no data that allow to determine a phenotypic and genotypic portrait of NDM forms or to explain the factors determining their occurrence. Further studies of clinical cases of neonatal diabetes are therefore required to determine the characteristics of NDM subtypes with subsequent disease prognosis.
The prevalence of hypogonadism in men with type 2 diabetes mellitus in clinical practice
Authors: Melnichenko Galina A. , Shestakova Marina V. , Rozhivanov Roman V.
Published: June 2019

BACKGROUND: Hypogonadism is a common complication in men with type 2 diabetes mellitus (DM), but its prevalence remains unknown.
AIMS: To estimate the prevalence of hypogonadism in men with type 2 DM.
MATERIALS AND METHODS: Male patients with type 2 DM were enrolled into a single-cohort contemporaneous multicenter non-interventional screening study. The study period was from November 2017 through August 2018. Assessments included total testosterone, luteinizing hormone (LH), sex hormone-binding globulin, HbA1c levels. Levels of free testosterone were calculated by Vermeullen method.
RESULTS: TheThe median of age of 400 included men was 56 years [51; 58], total testosterone was 12.3 [9.2; 16.5] nmol/l, free testosterone 270 [217; 334] pmol/l, HbA1c 7,1% [6.1; 8.6]. Hypogonadism was found in 135 men (33.7%). The total testosterone level in that group was 7.9 [6.8; 9.8] nmol/l, and free testosterone 192 [164; 227] pmol/l. In hypogonadism-free men their levels were 15,1 [12,4; 18,6] nmol/l and 311 [270; 364] pmol/l, respectively. In most patients with hypogonadism LH level was low, but within normal ranges, and significantly lower than in men without hypogonadism 3.2 [2.1; 4.7] IU/L vs 3.8 [2.7; 4.9] IU/L, respectively (p=0.007). Most commonly hypogonadism was with normal LH levels (92,6%, median LH level 3.2 [2.2; 4.3] IU/L, p0,001). The frequency of hypogonadism with high LH level (10.2 [9.2; 14.7] IU/L) and low LH level (1.0 [0.6; 1.1] IU/L) was 4.4% and 3.0%, respectively.
CONCLUSIONS: The prevalence of hypogonadism in men with type 2 DM was found to be 33.7%. Normal levels of LH are typical for this type of patients with hypogonadism.
Psychosocial aspects of the usage of modern technologies in diabetes mellitus
Authors: Motovilin Oleg G. , Surkova Elena V. , Baburyan Anush S. , Ibragimova Lyudmila I. , Mayorov Alexander Y.
Published: June 2019

This article represents a review of trials on the relationship between the use of modern technologies in the treatment of diabetes, such as continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM), and the psychological characteristics of patients. The review includes Russian studies and foreign publications.
The analysis showed that the psychological aspects of using CSII are considered more often than CGM. Most Russian authors agree that the use of technology is associated with an increased psychological well-being of patients. Foreign researchers generally agree with the same point of view but also report a weaker correlation.
One of the most significant conclusions of this analysis is that the use of modern technologies itself does not guarantee an improved quality of life (QOL) and psychological well-being, but technologies such as CSII and CGM provide patients with opportunities to achieve greater effectiveness in treating diabetes, improving clinical and metabolic parameters and therefore improving QOL. However, the use of these devices, as well as many other technological tools, is associated with certain psychological problems, both in terms of their acquisition and influence on patients subjective well-being. Early diagnosis and prevention of such problems should be one of the tasks in preparing patients for the use of modern technologies. A positive effect on both clinical and metabolic indicators as well as on the mental sphere and social life of patients can be achieved only by combining complete training (optimallyaccording to specialised programmes) with medical support.
Opportunities and options for surrogate assessment of insulin resistance
Authors: Ruyatkina Lyudmila A. , Ruyatkin Dmitry S. , Iskhakova Irina S.
Published: June 2019

The high prevalence of type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular diseases (CVD) determines the need for early detection and correction of key markers of cardio-metabolic risk (CMR). This prophylactic direction is closely related to metabolic syndrome (MS) based on the concept of insulin resistance (IR). At the same time, IR is the first link in the pathogenesis of T2DM and is a recognized risk factor for atherothrombosis. Therefore, early diagnosis of IR is of practical importance both for the detection of early disorders of carbohydrate metabolism (DCM) and prognosis of T2DM, and cardiological risk. Alternative indicators have been proposed for evaluating IR with the inclusion of lipid and anthropometric parameters, the diagnostic and prognostic significance of which in terms of CMR (DCM and CVD) has been evaluated in randomized clinical trials in comparison with the HOMA-IR index and clamp. The TyG index (calculated on the basis of plasma glucose and triglycerides) is consistent with the phenomenon of glucolipotoxicity with subsequent metabolic disorders in target organs. Its derivatives are proposed: TyG-WC (TyG / waist circumference) and TYG-BMI (TyG / BMI). Apply LAP indices (lipid accumulation index) and VAI (visceral obesity index), as well as TG / HDL (TG / HDL). Their ethnic and gender differences were revealed, attempts were made to calculate the cut-off points for these indices.
Epidemiological features of obesity in children and adolescents in the Udmurt Republic
Authors: Larionova Mariya A. , Kovalenko Tatiana V.
Published: June 2019

BACKGROUND: Obesity is one of the most frequent chronic diseases in the world. The true prevalence of obesity in the Russia significantly exceeds the data of official statistics and remains at the moment insufficiently studied.
AIM: to study the main epidemiological features of obesity in children and adolescents in the Udmurt Republic (UR).
MATERIALS AND METHODS: The data of official statistics for the period from 2005 to 2016 were analyzed. A total of 9662 children aged 117 years living in large cities and rural areas of the UR were examined (the ratio of urban and rural residents was 1:1), of which 4795 boys (49.6%), girls 4867 (50.4%). Age features of the disease were analyzed in groups of 13 years, 37 years, 712 years, 1215 years, over 15 years. At the standard deviation (SD) values of the body mass index (BMI) from +1 to +2 SD, excess body weight was diagnosed, with an excess of +2 SD obesity. The degree of obesity was assessed according to the classification of V.A. Peterkova et al. (2014) Epidemiological data were calculated for 1000 surveyed.
RESULTS: Official statistics showed a steady increase in the prevalence of obesity: in the 014 age group, the indicator (per 1000 children's population) increased from 5.4 (2005) to 16.2 (2016), among adolescents 1517 years from 7,5 to 45,4 respectively. In the epidemiological survey, overweight was recorded in 166,5 children, obesity in 67.1 (per 1000 surveyed). Data on a higher incidence of obesity in rural residents compared to urban residents (7.3% and 6.1%, respectively, p 0.05) were obtained. The disease was more often registered in boys (8,7%, in girls 4.7%, p 0.05). Thehighest prevalence of overweight was registered is 13 years (217.4 per 1000 people surveyed), of obesity 712 years (93.1 per 1000 people surveyed). The lowest prevalence rates of both overweight and obesity are registered in the age group over 15 years.
СONCLUSIONS: The study showed the importance of the problem of obesity in children and adolescents in the region.
Inflammation of adipose tissue. Is there a place for statins to correct adiposopathy?
Authors: Borodkina Daria A. , Gruzdeva Olga V. , Palicheva Elena V. , Barbarash Olga L.
Published: June 2019

This review is devoted to the analysis of data on the effect of inhibitors of 3-hydroxy-3-methylglutaryl coenzymate-reductase on the endocrine function of adipose tissue in obesity. Violation of metabolism of adipose tissue, as well as the amount of fat, are a a key factor in the pathophysiology of obesity and the development of concomitant diseases. Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl-kofermenta reductase (HMG-COA reductase) that catalyze the initial stage of cholesterol biosynthesis in the liver. Therefore, traditionally, the liver is considered as the main target organ for statins. The results of studies of molecular mechanisms of action of statins on carbohydrate and lipid metabolism, adipokine and inflammatory balance in adipose tissue on the example of isolated adipocytes (in vivo) and in living organism (in vitro) are presented. Effect of statins on the action of insulin, as well as the possibility of developing pathological conditions associated with insulin resistance and the development of type 2 diabetes mellitus (DM 2). The proven clinical effects of cholesterol-lowering action of statins, allow new insights and to further explore their possible impact on other links in the development of obesity, and potentially to use them as therapeutic agents for pharmacological correction of obesity and the fight against cardiovascular diseases.
The significance of circulating progenitor cells with osteogenic activity in the of atherosclerosis development in patients with type 2 diabetes mellitus
Authors: Michurova Marina S. , Kalashnikov Victor Yu. , Smirnova Olga M. , Stepanova Svetlana M. , Zakharov Alexander S. , Shestakova Marina V. , Dedov Ivan I.
Published: June 2019

BACKGROUND: There is an interaction between cell-mediated pathway of the vessel calcification and atherosclerosis processes. In some studies the relation beeen circulating osteogenic progenitor cells and cardiovascular diseases was shown. Though its role in the development of cerebrovascular diseases (CVD) in Type 2 diabetes mellitus (T2DM) remains unknown.
AIM: To study the level of circulating endothelial (CD34 + VEGFR2 +) and osteogenic (CD34 + OCN +) progenitor cells in patients with CVD and T2DM.
METHODS: We observed patients with CVD (coronary artery disease and / or chronic limb threatening ischemia) with T2DM and without T2DM. Patients with CVD and T2DM were included in group 1 patients with CVD and without T2D were included in group 2. The level of CD34 + VEGFR2 cells and CD34 + OCN+ cells was determined by flow cytometry.There were no differences in the age, gender, lipid profile, body mass index, creatinine clearance, myocardial revascularization and lower limb revascularization between the 2 groups.The level of CD34 + VEGFR2 cells and CD34 + OCN+ cells was determined by flow cytometry. The number of cells was determined by a percentage of the number of CD34+ cells.
RESULTS: We observed 71 patients (38 women, mean age 67 years [62, 74]). Forty six patients were included in group 1 (28 women, mean age 68 years [63;75], 25 patients (10 women, 66 years [55;72]) were included in group 2. We found that in patients with CVD and T2DM demonstrated higher amounts of CD34+OCN+ cells than CD34+VEGFR2+ cells. (29.7% [26.2;36.1] and 11.8% [9.57;17.2], p0.001). In the 1st group observed higher amounts of CD34+OCN+ cells, than in the 2d group (29.7 [26.2;36.1] и 25.6 [17.3;30.7] соответственно; p=0.035). Positive correlation was established between amount of CD34+OCN+ cells and atherogenic lipid fraction, LDL (r=0.4; р=0.032) and total cholesterol (r=0.27; р=0.05) in patients of group 1.While SYNTAX score tertiles and amount of CD34+OCN+ cells (r = 0.50, p=0.021) were the positive correlation. Between coronary artery calcium score and amount of CD34+OCN+ cells (r = 0.49, p=0.034) was the positive correlation.
CONCLUSIONS: Acquired results may indicate the active role of CD34+OCN+ endothelial progenitor cells in atherosclerosis and vascular calcification in patients with T2DM.
Estrogen metabolism, lifetime methylation disorders, and breast cancer
Authors: Chagay Natalia B. , Mkrtumyan Ashot M.
Published: June 2019

Oncogenesis can be caused by an increase in the activity of genes responsible for initiating tumor growth in stem or progenitor cells, as well as a reduction in the functioning of suppressor genes. Endogenous estrogen exposure is associated with an increased risk of breast cancer in both pre- and postmenopausal women.
The most important step in the understanding of the pathogenesis of breast cancer was the development of the theory of the switching of estrogen’s effect from hormonal to genotoxic, in which the main culprits of carcinogenesis are not chemical metabolites of estrogens, but their derivatives, corresponding to chemical procarcinogens according to their damaging characteristics. The origin of these substances and the formation of estrogen genotoxicity lies in the disruption of the inactivation process of catechol estrogens in methylation reactions.
The main epigenetic modification of the human genome is the methylation of cell DNA molecules. DNA methylation does not alter the primary sequence of nucleotides, but is necessary for the functional suppression of certain genes. The phenomenon of hypomethylation-hypermethylation underlies the long-term silencing of various genes, including tumor suppressor genes.
Nutrition and a lifestyle associated with smoking and the consumption of excessive quantities of alcohol determine estrogen metabolism and the availability of methyl groups in the body, as well as epigenetic changes in the DNA of the genome. The assessment of individual risk of breast cancer on the basis of an assay for the expression and methylation of the COMT gene responsible for estrogen metabolism seems relevant.
Mechanisms for the development of arterial hypertension in overweight adolescents and young adults
Authors: Mustafayeva Aynur G.
Published: June 2019

In recent years, an increase in the number of young people with arterial hypertension (AH) has occurred together with the increased prevalence of obesity. It is generally recognized that obesity plays an important role in the pathogenesis of hypertension in adolescents and young adults. In adolescents of non-European ethnicity with a family history of disease, a low birth weight and sedentary lifestyle, and insufficient physical activity and poor sleep quality, excess weight is accompanied by a high probability of AH. High tolerance to cardio-respiratory exertion and a number of genetic polymorphisms can play a protective role against this pathology. Biochemical studies in young people with hypertension and excess weight display a number of features, including levels of hormones and enzymes of the renin-angiotensin system, associated with lipid metabolism and inflammation. Adolescents with hypertension can be included in the group of young people at high risk of damage to affected organs and the subsequent development of cardiovascular diseases, based on a number of characteristics: blood pressure readings, BMI, age, family history and ethnicity.
Das utilidades da literatura
Authors: Cipreste Karla , Chagas Pedro D. , Saltarelli Thiago
Published: June 2019

Apresentamos artigos que defendem a utilidade da literatura, com discussões sobre sua contribuição para o desenvolvimento da mente, para a evolução cultural e para a formação humana.
La utilidad de la ficción en la poesía
Authors: Palma Castro Alejandro
Published: June 2019

En este artículo realizo un recorrido por la poesía desde la Edad Media hasta la época contemporánea revisando casos singulares donde se manifiesta la ficción. A partir de una lectura pragmática de estos poemas, en específico la enunciación, demuestro cómo la ficción más que una característica del lenguaje literario ha sido un medio que nos ha permitido interpretar y hasta crear la realidad desde nuevas experiencias. En la poesía trovadoresca, por ejemplo, es destacable cómo su ficción permitió la creación de saberes culturales que subsisten y han determinado nuestra época. También en la Edad Media, una cantiga del rey de Portugal, Don Dinis, pone en perspectiva el desarrollo cultural y económico de su reino. Posteriormente destaco al enunciador del célebre Primero sueño de Sor Juana Inés de la Cruz como experiencia posible de un sujeto femenino no contemplado en los cerrados esquemas sociales del virreinato. Concluyo el recorrido con un análisis sobre la evanescencia del sujeto poético en la poesía de Leopoldo María Panero como posibilidad para encarar el temor a la muerte. Este recorrido argumental me permite concluir que la poesía ha hecho uso de la ficción de una manera distinta a otros géneros literarios pero poco hemos reflexionado y caracterizado su procedimiento.
A intrahistoria de Manuel Rivas e as luzes da literatura sobre as sombras do passado
Authors: Cipreste Karla , Gregório Isabella Borges
Published: June 2019

O presente artigo analisa alguns aspectos da obra ¿Qué me quieres, amor? do escritor galego-espanhol Manuel Rivas à luz da reflexão do próprio autor sobre seu estilo como uma intrahistoria que, por ser literária, transfigura as sombras do passado em arte. Defendemos que seu estilo, contemporâneo, mas não pós-moderno, revela uma crença no papel edificante da literatura.
STEM Eğitimi Alanında Yapılan Yayınların Bibliyometrik Analizi
Authors: ÖZKAYA Ali
Published: June 2019

Çalışmada
STEM eğitimi konu alanında yayımlanan bilimsel araştırmaların bibliyometrik
analizi gerçekleştirilmiştir. Bu kapsamda alana yönelik bilimsel birikimin
iletişim yapısının genel görünümü objektif bir yöntemle, veriye dayalı olarak
ortaya konmaya çalışılmıştır. Bu kapsamda, STEM Eğitimi hakkında 1992-2017
yılları arasında yayımlanan 2313 çalışma bibliyometrik açıdan incelenmiş, son
26 yıldaki eğilim ortaya konmuştur. Web of Science Core Collection veri
tabanında “STEM Eğitimi” konu başlığında tarama gerçekleştirilmiş ve
çalışmalara ait bibliyometrik verilere ulaşılmıştır. Çalışmalar; yıllara göre
yayın sayıları, yayın türleri, yayın dilleri, atıf analizleri, ülke
işbirliktelikleri, ortak atıf ağları ile kavram-konu yönelimleri alt
başlıklarında incelenmiştir. Ortak atıf ağları ile kavram-konu yönelimlerinin
belirlenmesinde sosyal ağ analizi kullanılmıştır. Veri setinde yer alan
çalışmaların ortak atıfta bulunduğu yazarlar ve eserler de çalışma kapsamında
incelenmiştir.  Böylece, STEM eğitimi
konu alanında araştırmalar yapan önemli yazarların ve meydana getirdikleri
eserlerin belirlenmesi ve aralarındaki etkileşimlerin tespit edilmesi
amaçlanmıştır. Ayrıca çalışmada, STEM eğitimi alanında yayımlanan ve veri
setinde yer alan araştırmalarda kullanılan kavramların belirlenmesi için kelime
analizi gerçekleştirilmiştir. Analizler sonucunda işbirliktelikler ve ilişki
örüntüleri bilişsel haritalar şeklinde görselleştirilmiştir. Çalışmada ayrıca
ülke işbirliktelikleri, atıf kaynağı dergiler, yazarlar, yayınlar ile
kavramların ağdaki konumları değerlendirilmiş, 
veri setinde yer alan araştırmaların atıfta bulunduğu yazarlara,
eserlere ve bu eserlerin yayımlandığı önemli dergilere yönelik olarak da atıf
patlamaları tespit edilmiştir.
Penilaian Kualitas Desain Perguruan Tinggi dengan Menggunakan Pendekatan CPTED di Kota Semarang
Authors: Hapsari Dini Oktaviani , Susanti Retno
Published: June 2019

The existence of Undip and Unika in Semarang become the main attraction for students who are outside Semarang. It can increase the activity around Undip and Unika areas. Nevertheless, there are some new things happening around the campus area, in September 2017, there were reports of loss of 34 motorcycles, 133 helmets and 1 rearview mirror in Undip. Meanwhile, Unika has a case of murder that killed a man outside the exit gate of Unika in 2014. Therefore to minimize the crime case it is necessary to "Crime Prevention through Environmental Design (CPTED)" in campus area, can improve students' sense of security on the two campuses. In this research, to achieve the result of design quality, the method of analysis used is descriptive quantitative method. Analytical technique used is Analytical Hierarchy Process (AHP) and scoring using categorical given in the form of descriptive quantitative. Results of research that determine in Undip are in the sufficient category with 2,079 and the Unika category is in good category with a score of 2,378. These differences can be influenced by factors such as land area, contour, building density, area, number of students, and number of activities, which can cause facilities and policies to reduce crime and improve security at Undip and Unika.
Karakteristik Taman Menteri Soepeno sebagai Taman Ramah Anak di Kota Semarang
Authors: Prihantini P , Kurniawati Wakhidah
Published: June 2019

The child-friendly city is a city that gives attention to and recognizes the existence of children's rights, including the provision of children's play facilities. Public facilities that can reflect recognition of children's rights are parks. The purpose of this study is to find out the characteristic of Menteri Soepeno park as a child-friendly park in Semarang city. This park is expected to be a reference for the development of child-friendly parks in realizing a child-friendly city. The method used in this research is quantitative with scoring analysis. The result showed that Menteri Soepeno park was not child-friendly, some improvements were needed so this park could be one of facility that supports the realization of a child-friendly city in Semarang.
Comparação entre dispositivos de galgamento costeiro com rampa única e com rampa dupla empregando espectro de ondas e design construtal
Authors: Corrêa Martins Jaifer , Moraes Goulart Marcelo , Domingues dos Santos Elizaldo , André Isoldi Liércio , Das Neves Gomes Mateus , Oliveira Rocha Luiz Alberto
Published: June 2019

Estudos sobre formas alternativas de geração de energia elétrica vêm aumentado nos últimos anos. Os conversores de energia das ondas (wave energy converter - WEC) são uma destas formas, dentre elas o dispositivo de galgamento destaca-se por seu princípio de funcionamento. No presente trabalho é avaliado geometricamente um dispositivo de galgamento com rampa dupla, com a finalidade de maximizar a potência disponível ((Pd)m), este resultado é então comparado com o obtido para um dispositivo com rampa única, este referente a um trabalho encontrado na literatura. O método Design Construtal é usado na avaliação geométrica (determinação de um campo de busca) e o método Busca Exaustiva para a otimização. Para a geração da onda se utilizou o espectro de ondas Pierson-Moskowitz (PM), com período de onda e altura significativa de, respectivamente, TS = 7,5 s e HS = 1,5 m. As dimensões das rampas do dispositivo são obtidas em relação a fração de área da rampa (ϕ1 = 0,0006; 0,0009; 0,0012 e 0,0015; e ϕ2 = 0,0006, além das razões entre as alturas e comprimentos das rampas iguais: H1/L1 = 0,3 e H2/L2 = 0,2 e 0,3. Os resultados mostram que, para o dispositivo com rampa dupla, a aplicação do Design Construtal foi importante para avaliação geométrica, possibilitando determinar a potência disponível máxima para as condições impostas. Porém, em comparação com o dispositivo com rampa única, este mostrou-se uma opção melhor
Análise tarifária em instalações elevatórias de água – cenários para mitigação do impacto econômico das faturas de energia elétrica
Authors: Steffens Daniel Rocha , Silva Eglon Silveira , Rocha Luiz Alberto de Oliveira , Wander Paulo Roberto
Published: June 2019

Este artigo tem por objetivo avaliar a situação econômico-operacional de uma estação elevatória de água bruta, que atende a dois grandes municípios do sul do Brasil, frente ao estabelecido na resolução normativa n° 414, de 09 de setembro de 2010, da ANEEL. A instalação é composta de cinco conjuntos motobombas que são acionados de acordo com as sazonalidades do consumo de água tratada no sistema de abastecimento. Na configuração de projeto, dois conjuntos motobombas eram reservas operacionais e, portanto, até três equipamentos eram acionados de maneira paralela. A partir de janeiro de 2016, por uma necessidade operacional de maior vazão disponibilizada ao sistema de abastecimento, um dos equipamentos reservas foi colocado em operação. Com esse aumento do volume captado de água bruta e frente aos valores elevados das faturas de energia elétrica, o presente estudo se concentrou na análise de dados anuais operacionais, propondo, com o uso do software EPANET 2.0, o estabelecimento de possíveis cenários que possam resultar em diminuição dos valores pagos à companhia de energia elétrica. Objetivo esse que pode ser atingido através de duas alternativas: contratação de nova modalidade tarifária e/ou diminuição do número de conjuntos motobombas acionados durante o horário de ponta (com ou sem alterações da demanda contratada). As simulações demonstraram que é viável a diminuição do número de conjuntos motobombas acionados, bem como a diminuição do valor da demanda contratada para o mesmo período. Valores próximos aos 21.136,00 R$ mês-1 ou 253.632,00 R$ ano-1 podem ser alcançados com aplicação de simples medidas operacionais/contratuais.
Reconstruction of Tesla micro-valve using topological sensitivity analysis
Authors: Abdelwahed M. , Chorfi N. , Malek R.
Published: June 2019

In this paper, we deal with topology optimization attributed to the non stationary Navier-Stokes equations. We propose an approach where we analyze the sensitivity of a shape function relating to a perturbation of the flow domain. A numerical optimization algorithm based on topological gradient method is built and applied to the 2D Tesla micro valve reconstruction. Some numerical results confirm the efficiency of the proposed approach.
Morphology and Dynamics of the Baltic Sea Shore within Kaliningrad Oblast (Overview)
Authors: Babakov Aleksandr
Published: June 2019

A review of morphological and morphodynamic studies of the coast of the Kaliningrad oblast has been carried out for half a century. The studies include monitoring measurements by the Atlantic Branch of the Shirshov Institute of Oceanology of the Russian Academy of Sciences (AB IO RAS) with the participation of the state institute Baltberegozashchita (BBZ), as well as pre-war studies and cartographic analyses of long-term coastline migration carried out by the private company Baltic Aerogeodetic Enterprise (BaltAGE). It shows the spatial alternation of abrasive and accumulative areas, as well as frequent changes in beach width and height within the same morphological coast type. A change in the development trend of particular coast sections from year to year was noted. The significant influence of anthropogenic factors on the coastal development was emphasized, including changes in the direction of coastal retreat/advance along an extensive coastal stretch. Comparison of the interannual and nearly century-old dynamics of the coast revealed noticeable differences between them, with opposite trends in several large-scale coast sections.
Simulation of Sea-ice Thermodynamics by a Smoothed Particle Hydrodynamics Method
Authors: Staroszczyk Ryszard
Published: June 2019

The paper deals with the problem of sea-ice pack motion and deformation under the action of wind and water drag forces. Differential equations describing the behaviour of ice, with its very distinct material responses in converging and diverging flows, express the mass and linear momentum balances on a horizontal plane (the free surface of the ocean). The thermodynamic effects (ice melting and lead water freezing) are accounted for by adding source terms to the equations describing the evolution of the ice thickness and area fraction (concentration). These thermodynamic source terms are described by means of a single function that idealizes typical ice growth-rates observed in winter in the Arctic. The equations governing the problem are solved by a fully Lagrangian method of the smoothed particle hydrodynamics (SPH). Assuming that the ice behaviour can be approximated by a non-linearly viscous rheology, the proposed SPH model was used to simulate the flow of a sea-ice pack driven by wind drag stresses and varying seasonal temperatures. The results of numerical simulations illustrate the evolution of an ice pack, including distributions of ice thickness and ice area fraction in space and time for assumed temperature distributions.
Novel Combined Feeding Approach to Produce Quality Al6061 Composites for Heat Sinks
Authors: Asokan Manivannan , Rathinasabapathy Sasikumar , Khadar Shaik Dawood Abdul , Khan Mohammed Sadique
Published: June 2019

This elementary work aims to address agglomeration and non-uniform dispersion of reinforcement particles in stir casting using Al6061 alloy (AA 6061) as a matrix and Aluminium oxide (Al2O3) as reinforcement particles. A novel combined feeding method of Encapsulate feeding technique & Two Step Stir Casting was developed & attempted to produce good quality composites by varying weight fractions of Aluminium Oxide (0 to 5 wt.%). The wetting agent Mg (2 wt.%) added in all castings to ensure better binding between ceramics and matrix. The SEM photomicrograph ensures homogenous dispersion of reinforcement particles by combined feeding method. The thermal properties of produced good quality composites are enhanced with increase in Aluminium Oxide (Al2O3) from 0 to 5 wt.%.
Revisiting the Euro’s Trade Cost and Welfare Effects
Authors: Felbermayr Gabriel , Steininger Marina
Published: June 2019

When, about twenty years ago, the Euro was created, one objective was to facilitate intra-European trade by reducing transaction costs. Has the Euro delivered? Using sectoral trade data from 1995 to 2014 and applying structural gravity modeling, we conduct anex postevaluation of the European Monetary Union (EMU). In aggregate data, we find a significant average trade effect for goods of almost 8 percent, but a much smaller effect for services trade. Digging deeper, we detect substantial heterogeneity between sectors, as well as between and within country-pairs. Singling out Germany, and embedding the estimation results into a quantitative general equilibrium model of world trade, we find that EMU has increased real incomes in all EMU countries, albeit at different rates. E. g. incomes have increased by 0.3, 0.6, and 2.1 percent in Italy, Germany, and Luxembourg, respectively.
On two sublattices of the subgroup lattice of a finite group
Authors: Chi Zhang , Skiba Alexander N.
Published: June 2019

Let

𝔉

{\mathfrak{F}}

be a non-empty class of groups, let G be a finite group and let

ℒ
⁢

(
G
)

{\mathcal{L}(G)}

be the lattice of all subgroups of G.
A chief

H
/
K

{H/K}

factor of G is

𝔉

{\mathfrak{F}}

-central in G if

(

H
/
K

)

⋊

(

G
/

C
G

⁢

(

H
/
K

)

)

∈
𝔉

{(H/K)\rtimes(G/C_{G}(H/K))\in\mathfrak{F}}

.
Let

ℒ

c
⁢
𝔉

⁢

(
G
)

{\mathcal{L}_{c\mathfrak{F}}(G)}

be the set of all subgroups A of G such that every chief factor

H
/
K

{H/K}

of G between

A
G

{A_{G}}

and

A
G

{A^{G}}

is

𝔉

{\mathfrak{F}}

-central in G;

ℒ
𝔉

⁢

(
G
)

{\mathcal{L}_{\mathfrak{F}}(G)}

denotes the set of all subgroups A of G with

A
G

/

A
G

∈
𝔉

{A^{G}/A_{G}\in\mathfrak{F}}

.
We prove that the set

ℒ

c
⁢
𝔉

⁢

(
G
)

{\mathcal{L}_{c\mathfrak{F}}(G)}

and, in the case when

𝔉

{\mathfrak{F}}

is a Fitting formation, the set

ℒ
𝔉

⁢

(
G
)

{\mathcal{L}_{\mathfrak{F}}(G)}

are sublattices of the lattice

ℒ
⁢

(
G
)

{\mathcal{L}(G)}

.
We also study conditions under which the lattice

ℒ

c
⁢
𝔑

⁢

(
G
)

{\mathcal{L}_{c\mathfrak{N}}(G)}

and the lattice of all subnormal subgroup of G are modular.
The synthesis and crystal structure of isobutyl 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carboxylate, C16H13Cl2F6N3O3S
Authors: Chen Lianqing , Du Yanting
Published: June 2019

C16H13Cl2F6N3O3S, monoclinic, P21/n (no. 14), a = 5.8650(10) Å, b = 30.196(5) Å, c = 11.777(2) Å, β = 96.619(2)°, V = 2071.8(6) Å3, Z = 4, R
gt(F) = 0.0521, wR
ref(F
2) = 0.1211, T = 173 K.
Crystal structure of poly[μ2-1,4-bis((1H-imidazol-1-yl)methyl)benzene-κ2
N:N′)-(μ2-4-sulfidobenzoate-κ2
O:S)cobalt(II)] dihydrate, C42H44Co2N8O7S2
Authors: Yin Chonglan , Jiang Wei , Dai Jihong
Published: June 2019

C42H44Co2N8O7S2, monoclinic, P21 (no. 4), a = 7.3941(6) Å, b = 15.3043(14) Å, c = 9.7831(7) Å, β = 101.315(7)°, V = 1085.56(15) Å3, Z = 1, R
gt(F) = 0.0392, wR
ref(F
2) = 0.0749, T = 293(2) K.
Crystal structure of [(2-(2-chlorophenyl)-5-ethyl-1,3-dioxane-5-carboxylato-κ2
O,O′) (5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane-κ4
N,N′,N′′,N′′′)]nickel(II) perchlorate, C29H50Cl2N4NiO8
Authors: Guang-Chuan Ou , Jia Guo-Kai , Tan Ying-Zhi
Published: June 2019

C29H50Cl2N4NiO8, orthorhombic, Pbca (no. 61), a = 20.601(3) Å, b = 13.5059(16) Å, c = 25.015(3) Å, Z = 8, V = 6960.3(15) Å3, R
gt(F) = 0.0495, wR
ref(F
2) = 0.1652, T = 296(2) K.
Crystal structure of N
1,N
3-bis(2-hydroxyethyl)-N
1, N
1,N
3,N
3-tetramethylpropane-1,3-diaminium dibromide, C11H28Br2N2O2
Authors: Su Chang-Ming , Wang Chun-Hua , Hou Gui-Ge
Published: June 2019

C11H28Br2N2O2, triclinic, P1̄ (no. 2), a = 12.0519(11) Å, b = 12.6670(12) Å, c = 12.9161(12) Å, α = 117.088(3)°, β = 92.459(1)°, γ = 108.199(2))°, V = 1627.2(3) Å3, Z = 4, R
gt(F) = 0.0645, wR
ref(F
2) = 0.1632, T = 298(2) K.
Crystal structure of 2-oxo-1-(pyrimidin-5-ylmethyl)-3-(3-(trifluoromethyl)phenyl)-1,2-dihydro-5l4-pyrido[1,2-a]pyrimidin-4-olate, C20H13F3N4O2
Authors: Yun-lian Shi , Tao Huang , Xu-Liang Nie , Feng-Rong Zhang , Da-Yong Peng , Xu-Gen Shi , Bao-Tong Li
Published: June 2019

C20H13F3N4O2, triclinic, P1̄ (no. 2), a = 11.3525(10) Å, b = 12.7530(11) Å, c = 13.1926(12) Å, α = 83.894(1)°, β = 69.314(1)°, γ = 84.720(1)°, V = 1773.7(3) Å3, Z = 4, R
gt(F) = 0.0477, wR
ref(F
2) = 0.1433, T = 296(2) K.
Innovación y TIC en el paisaje sonoro de la música festera a través de la creación de musicomovigramas
Authors: Botella Nicolás Ana María , Hurtado Soler Amparo , Ramos Ahijado Sonsoles
Published: June 2019

Este artículo es parte de un proyecto de investigación sobre el paisaje sonoro, la escucha y la creación y recreación de espacios de educación ambiental y musical. Consiste en una propuesta de creación y utilización de un recurso auditivo-didáctico e interactivo, el musicomovigrama o musicograma en movimiento, para trabajar la escucha y el desarrollo emocional mediante la Fiesta y la música de Moros y Cristianos de Alcoy y su paisaje sonoro. La gran potencialidad de este recurso deriva de su capacidad para ofrecer al alumnado un soporte visual atractivo sincronizado con la progresión de la música que escucha, de tal manera que ambos códigos avancen simultáneamente. El objetivo principal es estudiar el paisaje sonoro y el entorno acústico, así como el medio natural y los sentidos, para incentivar la sensibilización auditiva en las aulas y fomentar la escucha activa y consciente de los diferentes entornos o paisajes sonoros, favorables o perjudiciales. Los resultados demuestran que este tipo de aplicaciones permite desarrollar la percepción del entorno dentro del aula con aproximaciones quasi-reales incrementando la conexión entre la percepción natural del medio y la expresión artística. La utilización de las TIC como herramientas transversales permite profundizar en la composición del paisaje visual y sonoro relacionando los sonidos ambientales con los instrumentos y seleccionando estilos musicales con base en el paisaje.[1] La ciudad de Alcoy y su término municipal ocupan una extensión de 130,61 kilómetros cuadrados, implicando con ello que es el municipio más extenso de todos los que forman su comarca. Dentro de la Comunidad Valenciana, forma parte de la provincia de Alicante y es la capital de la comarca de L´Alcoià.
Optimization of Hot Workability of Cu-Cr-Zr-Ti Alloy Through Development of a Processing Map
Authors: Sarkar Aditya , Narayana Murty S. V. S. , Prasad M. J. N. V.
Published: June 2019

Owing to high thermal conductivity, copper-based alloys are used to fabricate heat transfer elements of rocket engines, such as combustion chambers, nozzle liners, and metal gaskets. One such alloy is the Copper-Chromium-Zirconium-Titanium (Cu-Cr-Zr-Ti) alloy, which possesses a good combination of thermal conductivity and strength at high temperatures. Thermomechanical processing is an important step in the realization of the various aforementioned heat transfer elements from this alloy. Hence, it is imperative to understand the hot deformation behavior of the alloy as a function of the process variables such as temperature and strain rate. An attempt is made to study the hot deformation behavior of the Cu-Cr-Zr-Ti alloy by subjecting it to uniaxial hot compression tests in the temperature range of 600°C–800°C and strain rate range of 0.001–10 s−1. The flow stress measurement tests were conducted up to a true strain of 0.5 using a Gleeble 3800 simulator. The nature of the flow curves obtained at the completion of the tests indicated the occurrence of dynamic recrystallization (DRX) at deformation temperatures greater than 700°C and with a strain rate below 1 s−1. The work hardening rate was plotted as a function of effective flow stress to assess the flow softening behavior due to DRX at different deformation conditions. A processing map delineating the stable and unstable regions during hot working is developed and validated by observing the microstructures in the corresponding domains. Optimum processing parameters (temperature of 750°C and strain rate of 0.1–10 s−1) for hot working of the alloy were proposed based on a contour map of efficiency of power dissipation. Two constitutive equations are also established: one using the Hyperbolic sine law as proposed by Sellars and McTegart and the other using Kocks Mecking analysis.
3D Electron Microscopy Study of Synaptic Organization of the Normal Human Transentorhinal Cortex and Its Possible Alterations in Alzheimer’s Disease
Authors: Domínguez-Álvaro M. , Montero-Crespo M. , Blazquez-Llorca L. , DeFelipe J. , Alonso-Nanclares L.
Published: June 2019

The transentorhinal cortex (TEC) is an obliquely oriented cortex located in the medial temporal lobe and, together with the entorhinal cortex, is one of the first affected areas in Alzheimer’s disease (AD). One of the most widely accepted hypotheses is that synaptopathy (synaptic alterations and loss) represents the major structural correlate of the cognitive decline observed in AD. However, very few electron microscope (EM) studies are available; the most common method to estimate synaptic density indirectly is by counting, at the light microscopic level, immunoreactive puncta using synaptic markers. To investigate synaptic morphology and possible alterations related to AD, a detailed three-dimensional (3D) ultrastructural analysis using focused ion beam/scanning EM (FIB/SEM) was performed in the neuropil of Layer II of the TEC in human brain samples from non-demented subjects and AD patients. Evaluation of the proportion and shape of asymmetric synapses (AS) and symmetric synapses (SS) targeting spines or dendritic shafts was performed using 3D reconstructions of every synapse. The 3D analysis of 4722 synapses revealed that the preferable targets were spine heads for AS and dendritic shafts for SS, both in control and AD cases. However, in AD patients, we observed a reduction in the percentage of synapses targeting spine heads. Regarding the shape of synapses, in both control cases and AD samples, the vast majority of synapses had a macular shape, followed by perforated or horseshoe-shaped synapses, with fragmented synapses being the least frequent type. Moreover, comparisons showed an increased number of fragmented AS in AD patients.