bluuebunny/crossref_metadata_2025 huggingface dataset:
Patient satisfaction with preoperative nursing care and its associated factors in surgical procedures, 2023: a cross-sectional study
Authors: Ataro Bizuayehu Atinafu , Geta Temesgen , Endirias Eshetu Elfios , Gadabo Christian Kebede , Bolado Getachew Nigussie
Published: April 2024

Background

To enhance patient satisfaction, nurses engaged in preoperative care must possess a comprehensive understanding of the most up-to-date evidence. However, there is a notable dearth of relevant information regarding the current status of preoperative care satisfaction and its impact, despite a significant rise in the number of patients seeking surgical intervention with complex medical requirements.

Objective

To assess patient satisfaction with preoperative nursing care and its associated factors in surgical procedures of, 2023.

Methods

A cross-sectional study was conducted, and the data was collected from the randomly selected 468 patients who had undergone surgery during the study period. The collected data was entered into Epidata version 3.1 and analyzed using SPSS version 25 software.

Results

The complete participation and response of 468 participants resulted in a response rate of 100%. Overall patient satisfaction with preoperative nursing care was 79.5%. Sex (Adjusted odds ratio (AOR): 1.14 (95% confidence interval (CI): 0.21–2.91)), payment status for treatment (AOR: 1.45 (95% CI: 0.66–2.97)), preoperative fear and anxiety (AOR: 1.01, 95% CI: 0.49–2.13)), patient expectations (AOR: 3.39, 95% CI: 2.17–7.11)), and preoperative education (AOR: 1.148, 95% CI: 0.54–2.86)) exhibited significant associations with patient satisfaction with preoperative nursing care.

Conclusion

It is important to exercise caution when interpreting the level of preoperative nursing care satisfaction in this study. The significance of preoperative nursing care satisfaction lies in its reflection of healthcare quality, as even minor deficiencies in preoperative care can potentially lead to life-threatening complications, including mortality. Therefore, prioritizing the improvement of healthcare quality is essential to enhance patient satisfaction.
Parental satisfaction with neonatal intensive care unit services and associated factors in Ethiopia: systematic review and meta-analysis
Authors: Elfios Eshetu , Awoke Nefsu , Geta Temesgen , Kebede Christian , Hassen Abdulkerim
Published: April 2024

Background

In the context of healthcare, satisfaction is the attainment of adequate or acceptable treatment and serves as both a benchmark for quality and the ultimate objective of providing care. In neonatal care facilities, parent satisfaction is a key measure of the quality of the services offered to the newborns and aids in improving healthcare delivery. This is the first systematic review aiming to address critical knowledge gaps regarding factors influencing parental satisfaction with neonatal intensive care unit services, and determine pooled prevalence in Ethiopia.

Methods

After comprehensive systematic search for full texts in the English language through an electronic web-based search strategy from databases of PubMed, CINAHL, Embase, African Journals Online, PsycINFO, and Google Scholar, included a total of 8 articles. Checklists from the Joanna Briggs Institute were used to assess the studies’ quality of methodology. STATA version 14 software for windows was used for all statistical analyses and meta-analysis was done using a random-effects method. Subgroup and sensitivity analyses were performed to clarify the source of heterogeneity.

Results

Pooled national level of parents’ satisfaction with neonatal intensive unit service was 57.87% (95% CI (49.99, 65.75%)). Age of respondents and availability of chair were significantly associated with parents’ satisfaction with neonatal intensive unit service.

Conclusions and recommendation

In our review we found that nearly half of parents expressed dissatisfaction with neonatal intensive unit service, which is high. Age of respondents and availability of chair in neonatal intensive unit waiting area were significantly associated with neonatal intensive unit service. Efforts to enhance parental satisfaction with neonatal intensive unit services are crucial, given that nearly half of parents reported dissatisfaction. Necessary infrastructure should be fulfilled to increase parental satisfaction with neonatal intensive unit service.

(PROSPERO) International prospective register of systematic reviews:

CRD42023483474
The effect of physical barriers under a raised house on mosquito entry: an experimental study in rural Gambia
Authors: Carrasco-Tenezaca Majo , Jawara Musa , Bradley John , D’Alessandro Umberto , Jeffries David , Knudsen Jakob B. , Lindsay Steve W.
Published: April 2024

Background

Anopheles gambiae, the major malaria mosquito in sub-Saharan Africa, feed largely indoors at night. Raising a house off the ground with no barriers underneath reduces mosquito-house entry. This experiment tested whether walling off the space under an elevated hut affects mosquito-hut entry.

Methods

Four inhabited experimental huts, each of which could be moved up and down, were used in rural Gambia. Nightly collections of mosquitoes were made using light traps and temperature and carbon dioxide levels monitored indoors and outdoors using loggers. Each night, a reference hut was kept at ground level and three huts raised 2 m above the ground; with the space under the hut left open, walled with air-permeable walls or solid walls. Treatments were rotated every four nights using a randomized block design. The experiment was conducted for 32 nights. Primary measurements were mosquito numbers and indoor temperature in each hut.

Results

A total of 1,259 female Anopheles gambiae sensu lato were collected in the hut at ground level, 655 in the hut with an open ground floor, 981 in the hut with air-permeable walls underneath and 873 in the hut with solid walls underneath. Multivariate analysis, adjusting for confounders, showed that a raised hut open underneath had 53% fewer mosquitoes (95% CI 47–58%), those with air-permeable walls underneath 24% fewer (95% CI 9–36%) and huts with solid walls underneath 31% fewer (95% CI 24–37%) compared with a hut on the ground. Similar results were found for Mansonia spp. and total number of female mosquitoes, but not for Culex mosquitoes where hut entry was unaffected by height or barriers. Indoor temperature and carbon dioxide levels were similar in all huts.

Conclusion

Raising a house 2 m from the ground reduces the entry of An. gambiae and Mansonia mosquitoes, but not Culex species. The protective effect of height is reduced if the space underneath the hut is walled off.
MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus
Authors: Wang Tao , Song Dan , Li Xuejuan , Luo Yu , Yang Dianqiang , Liu Xiaoyan , Kong Xiaodan , Xing Yida , Bi Shulin , Zhang Yan , Hu Tao , Zhang Yunyun , Dai Shuang , Shao Zhiqiang , Chen Dahan , Hou Jinpao , Ballestar Esteban , Cai Jianchun , Zheng Feng , Yang James Y.
Published: April 2024

Endosomal single-stranded RNA-sensing Toll-like receptor-7/8 (TLR7/8) plays a pivotal role in inflammation and immune responses and autoimmune diseases. However, the mechanisms underlying the initiation of the TLR7/8-mediated autoimmune signaling remain to be fully elucidated. Here, we demonstrate that miR-574-5p is aberrantly upregulated in tissues of lupus prone mice and in the plasma of lupus patients, with its expression levels correlating with the disease activity. miR-574-5p binds to and activates human hTLR8 or its murine ortholog mTlr7 to elicit a series of MyD88-dependent immune and inflammatory responses. These responses include the overproduction of cytokines and interferons, the activation of STAT1 signaling and B lymphocytes, and the production of autoantigens. In a transgenic mouse model, the induction of miR-574-5p overexpression is associated with increased secretion of antinuclear and anti-dsDNA antibodies, increased IgG and C3 deposit in the kidney, elevated expression of inflammatory genes in the spleen. In lupus-prone mice, lentivirus-mediated silencing of miR-574-5p significantly ameliorates major symptoms associated with lupus and lupus nephritis. Collectively, these results suggest that the miR-574-5p-hTLR8/mTlr7 signaling is an important axis of immune and inflammatory responses, contributing significantly to the development of lupus and lupus nephritis.
Exploring the decision-making process of female genital cosmetic procedures in Iranian women and constructing and validating a results-based logic model for a healthy public policy: a study protocol
Authors: Azmoude Elham , Zagami Samira Ebrahimzadeh , Hooshmand Elahe , Taheri Elham , Shoorab Nahid Jahani
Published: April 2024

Background

Female genital cosmetic procedures have grown rapidly in most parts of the world. Professional organizations have issued warnings about the complications and long-term consequences of these practices. To be able to adopt the right health policies, it is necessary to know why women decide to perform these procedures. Therefore, the present study will be aim to discover the decision-making process involved in performing female genital cosmetic procedures for Iranian women and construct and validate a results-based logic model for healthy public policy.

Methods

The present study was conducted in three phases. In the initial phase, a qualitative study will be conducted with the Corbin and Strauss ground theory approach. The participants in the study will be healthy women who desire or have undergone female genital cosmetic procedures without medical indications. In this phase, purposive and theoretical sampling will guide recruitment and data collection. The data will be collected via semi-structured interviews, field notes and observations of individual interactions. The data will be analysed using the approach of Corbin and Strauss (2015). MAXQDA 2007 software was used for managing the process of data analysis. In the second phase, the development of a results-based logic model for a healthy public policy is performed based on the findings of the first phase of the study, interviews with key informants and a review of the results of the literature in this field. Finally, validation of the designed program will be performed by the nominal group technique with the presence of a group of experts in the third phase.

Discussion

The findings of this study, by identifying women’s main concerns related to the studied phenomenon, the existing context, participants’ reactions and the consequences of the adopted reactions, can be very important in designing a program that fits Iran’s cultural characteristics. In this research, a program using a logical model will be presented that is suitable for policymakers, planners and healthcare service providers to be implemented in the social-cultural context of the study.
Development of monoclonal antibodies against oropouche virus and its applicability to immunohistochemical diagnosis
Authors: Andreolla Ana Paula , Borges Alessandra Abel , Nagashima Seigo , Vaz de Paula Caroline Busatta , de Noronha Lucia , Zanchin Nilson I.T. , Bordignon Juliano , Duarte dos Santos Claudia Nunes
Published: April 2024

Orthobunyavirus oropouche ense virus(OROV), the causative agent of Oropouche fever, is widely dispersed in Brazil and South America, causing sporadic outbreaks. Due to the similarity of initial clinical symptoms caused by OROV with other arboviruses found in overlapping geographical areas, differential diagnosis is challenging. As for most neglected tropical diseases, there is a shortage of reagents for diagnosing and studying OROV pathogenesis. We therefore developed and characterized mouse monoclonal antibodies and, one of them recognizes the OROV nucleocapsid in indirect immunofluorescent (IFA) and immunohistochemistry (IHC) assays. Considering that it is the first monoclonal antibody produced for detecting OROV infections, we believe that it will be useful not only for diagnostic purposes but also for performing serological surveys and epidemiological surveillance on the dispersion and prevalence of OROV in Brazil and South America.
Recurrent cementoblastoma with multifocal growth and cellular atypia: a case report
Authors: Oya Kaori , Takeshita Akinori , Wakamori Kanta , Song Misa , Kimura Hayato , Hirose Katsutoshi , Shimamoto Hiroaki , Sato Sunao , Matsunaga Kazuhide , Uzawa Narikazu , Toyosawa Satoru
Published: April 2024

Background

Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high potential for growth with a certain degree of recurrence risk. However, there are only a few studies describing the features of recurrent cementoblastoma. The diagnosis of recurrent cementoblastoma is challenging not only due to its cytological atypia but also because of its large size and multicentric growth pattern. These characteristics suggest a potential for malignancy.

Case presentation

A 29-year-old woman was transferred to our university dental hospital complaining of swelling of the right mandible. She had a history of enucleation of cementoblastoma associated with the third molar of the right mandible. Five years after the initial treatment, imaging demonstrated well-circumscribed multicentric radiopaque lesions in the same area. Histologically, the lesion consisted of osteocementum-like tissue rimmed with polygonal or plump tumor cells. Several cells were large epithelioid cells with bizarre nucleoli, which may be reminiscent of malignant tumors. Otherwise, there were no apparent malignant findings, including proliferative activity or atypical mitotic figure. Besides, tumor cells were positive for c-FOS, a marker of osteoblastoma and cementoblastoma. Eventually, the patient was diagnosed with recurrent cementoblastoma.

Conclusions

Pathological analyses of this case suggested that the recurrent event in the cementoblastoma altered its growth pattern and tumor cell shape. Moreover, in the case of enucleation surgery, long-term follow-up is important because there is some recurrent risk of cementoblastoma, although it is not high.
The use of prescription medications and non-prescription medications during lactation in a prospective Canadian cohort study
Authors: Soliman Youstina , Yakandawala Uma , Leong Christine , Garlock Emma S. , Brinkman Fiona S.L. , Winsor Geoffrey L. , Kozyrskyj Anita L , Mandhane Piushkumar J , Turvey Stuart E. , Moraes Theo J. , Subbarao Padmaja , Nickel Nathan C. , Thiessen Kellie , Azad Meghan B , Kelly Lauren E
Published: April 2024

Background

A lack of safety data on postpartum medication use presents a potential barrier to breastfeeding and may result in infant exposure to medications in breastmilk. The type and extent of medication use by lactating women requires investigation.

Methods

Data were collected from the CHILD Cohort Study which enrolled pregnant women across Canada between 2008 and 2012. Participants completed questionnaires regarding medications and non-prescription medications used and breastfeeding status at 3, 6 and 12 months postpartum. Medications, along with self-reported reasons for medication use, were categorized by ontologies [hierarchical controlled vocabulary] as part of a large-scale curation effort to enable more robust investigations of reasons for medication use.

Results

A total of 3542 mother-infant dyads were recruited to the CHILD study. Breastfeeding rates were 87.4%, 75.3%, 45.5% at 3, 6 and 12 months respectively. About 40% of women who were breastfeeding at 3 months used at least one prescription medication during the first three months postpartum; this proportion decreased over time to 29.5% % at 6 months and 32.8% at 12 months. The most commonly used prescription medication by breastfeeding women was domperidone at 3 months (9.0%, n = 229/2540) and 6 months (5.6%, n = 109/1948), and norethisterone at 12 months (4.1%, n = 48/1180). The vast majority of domperidone use by breastfeeding women (97.3%) was for lactation purposes which is off-label (signifying unapproved use of an approved medication). Non-prescription medications were more often used among breastfeeding than non-breastfeeding women (67.6% versus 48.9% at 3 months, p < 0.0001), The most commonly used non-prescription medications were multivitamins and Vitamin D at 3, 6 and 12 months postpartum.

Conclusions

In Canada, medication use is common postpartum; 40% of breastfeeding women use prescription medications in the first 3 months postpartum. A diverse range of medications were used, with many women taking more than one prescription and non-prescription medicines. The most commonly used prescription medication by breastfeeding women were domperidone for off-label lactation support, signalling a need for more data on the efficacy of domperidone for this indication. This data should inform research priorities and communication strategies developed to optimize care during lactation.
Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds
Authors: Kar Tarun Kumar , Sil Sananda , Ghosh Angshita , Barman Ananya , Chattopadhyay Sandip
Published: April 2024

Background

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women that necessitates effective and safe treatment alternatives. This study aimed to evaluate the therapeutic efficacy of Vitex negundo seed in a letrozole-induced PCOS rat model.

Results

Findings of the present study demonstrated that administration of hydro-ethanolic extract of Vitex negundo (VNE) effectively restored endocrino-metabolic imbalances associated with PCOS, along with correction of antioxidant enzymes level, proinflammatory cytokines, and apoptotic bio-markers. LC-MS analysis confirmed the presence of cinnamic acid, plumbagin and nigundin B as the prominent phytochemicals in VNE. The observed beneficial effects could be attributed to the active compounds in Vitex negundo extract, which exhibited hypoglycemic, hypolipidemic, and catabolic effects on body weight. Additionally, the extract contributed to hormonal balance regulation by modulating the steroidogenic enzymes, specifically by tuning gonadotropins level and correcting the LH:FSH ratio, through the modulation of ERα signalling and downregulation of NR3C4 expression. The antioxidant properties of phytochemicals in Vitex negundo seed were apparent through the correction of SOD and catalase activity. While it’s anti-inflammatory and antiapoptotic action were associated with the regulation of mRNA expression of TNF-α, IL-6, BAX, Bcl2. Molecular docking study further indicated the molecular interaction of above mentioned active phytocompounds of VNE with ERα, NR3C4 and with TNFα that plays a critical mechanistic gateway to the regulation of hormone signalling as well as synchronizing the inflammation cascade. Furthermore, the histomorphological improvement of the ovaries supported the ameliorative action of Vitex negundo extract in the letrozole-induced PCOS model.

Conclusions

This study indicates the potential of Vitex negundo seed as a multifaceted therapeutic option for PCOS. VNE offers a holistic strategy for PCOS with antiandrogenic, anti-inflammatory, and antioxidant properties, driven by its major compounds like cinnamic acid, plumbagine, and nigundin B.
Genetic evolution and phylogenetic analysis of porcine epidemic diarrhea virus strains circulating in and outside China with reference to a wild type virulent genotype CHYJ130330 reported from Guangdong Province, China
Authors: Mohiuddin Mudassar , Deng Shengchao , Zhu Lisai , Wang Guiping , Jia Aiqing
Published: April 2024

During the last decade, porcine epidemic diarrhea virus has detrimental consequences on swine industry, due to severe outbreaks especially in the suckling piglets. In March 2013, an outbreak was reported on a commercial swine farm in Guangdong Province, Southern China. A wild-type PEDV strain named as CHYJ130330 was identified, complete genome was sequenced and deposited in GenBank (accession no. KJ020932). The molecular epidemiological including evolutionary characteristics and pathogenicity assessment were explored during this study with particular interest and focus to develop this candidate strain for new vaccine. The isolates from China pre- and post-2013 shared 96.5–97.2% and 97–99% nt identity respectively with wild-type CHYJ130330 strain which during experimental studies has demonstrated high virulence and 100% mortality in 104 TCID50 group piglets within 5 days. The 22 reference strains selected from other parts of the world shared 98–99% identity with our sequence except Chinese (CV777) and S. Korean (vir.DR13, SM98 and atten.DR13) strains sharing 96.8, 97.6, 96.6 and 97.1% identity respectively. The phylogenetic tree revealed most strains reported after 2013 in GII genogroup while the prototype (CV777), S.korean and earlier Chinese (JS2008, 85-7mutant, Atten.vaccine, SD-M, LZC and CH/S) were GI Group. The amino acid sequence of CHYJ130330 E and M protein is highly conserved while ORF3 and N protein having 9 and 17 amino acid substitutions respectively in comparison to CV777 strain. The comparison of full length genome and the structural proteins revealed variations signifying that PEDV variant strains are still the main source of outbreaks in spite of continuous vaccination and also explain the variable trend of large scale outbreaks during this decade as compared to sporadic tendency of disease found before 2010. It is evident from this study that Chinese strains display significant level of mixing with the strains reported from other countries. The strain CHYJ130330 was also adapted successfully to Vero cell line and has shown high virulence in piglets. The information/findings will be helpful to develop a strategy for control of PEDV and have also shown that CHYJ130330 strain has strong virulence and is a more popular clinical strain in recent years, which has the potential to be developed into PEDV vaccine.
On the multiparameterized fractional multiplicative integral inequalities
Authors: Almatrafi Mohammed Bakheet , Saleh Wedad , Lakhdari Abdelghani , Jarad Fahd , Meftah Badreddine
Published: April 2024

We introduce a novel multiparameterized fractional multiplicative integral identity and utilize it to derive a range of inequalities for multiplicativelys-convex mappings in connection with different quadrature rules involving one, two, and three points. Our results cover both new findings and established ones, offering a holistic framework for comprehending these inequalities. To validate our outcomes, we provide an illustrative example with visual aids. Furthermore, we highlight the practical significance of our discoveries by applying them to special means of real numbers within the realm of multiplicative calculus.
Assessing the impact of a cleaning programme on environmental hygiene in labour and neonatal wards: an exploratory study in The Gambia
Authors: Okomo Uduak , Gon Giorgia , Darboe Saffiatou , Sey Isatou C. M. , Nkereuwem Oluwatosin , Leigh Lamin , Camara Nfamara , Makalo Lamin , Keita Abdoulie , Dancer Stephanie J. , Graham Wendy , Aiken Alexander M.
Published: April 2024

Background

Effective surface cleaning in hospitals is crucial to prevent the transmission of pathogens. However, hospitals in low- and middle-income countries face cleaning challenges due to limited resources and inadequate training.

Methods

We assessed the effectiveness of a modified TEACH CLEAN programme for trainers in reducing surface microbiological contamination in the newborn unit of a tertiary referral hospital in The Gambia. We utilised a quasi-experimental design and compared data against those from the labour ward. Direct observations of cleaning practices and key informant interviews were also conducted to clarify the programme's impact.

Results

Between July and September 2021 (pre-intervention) and October and December 2021 (post-intervention), weekly surface sampling was performed in the newborn unit and labour ward. The training package was delivered in October 2021, after which their surface microbiological contamination deteriorated in both clinical settings. While some cleaning standards improved, critical aspects such as using fresh cleaning cloths and the one-swipe method did not. Interviews with senior departmental and hospital management staff revealed ongoing challenges in the health system that hindered the ability to improve cleaning practices, including COVID-19, understaffing, disruptions to water supply and shortages of cleaning materials.

Conclusions

Keeping a hospital clean is fundamental to good care, but training hospital cleaning staff in this low-income country neonatal unit failed to reduce surface contamination levels. Further qualitative investigation revealed multiple external factors that challenged any possible impact of the cleaning programme. Further work is needed to address barriers to hospital cleaning in low-income hospitals.
Cross-sectional association study of hedonic hunger, self-control, cognitive distortion, and well-being with adiposity measures among a sample of urban Malaysian adults
Authors: Say Yee-How , Nordin Mimi Shamirah , Ng Alvin Lai Oon
Published: April 2024

Background

We assessed the association of hedonic hunger, self-control (impulsivity and restraint), cognitive distortion (CD), and well-being with adiposity measures such as waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body mass index (BMI), total body fat (TBF), subcutaneous fat (SF), visceral fat level (VFL), skeletal muscle percentage (SM), and resting metabolism (RM), among a sample of urban Malaysian adults at Sunway University and Sunway College, Selangor, Malaysia.

Methods

Among 186 participants (M/F = 51/135; aged 22.1 ± 5.0), psychometrics were assessed using Power of Food Scale (PFS), Brief Self-Control Scale, CD Questionnaire (CD-Quest), and WHO-5 Well-being Index. Blood pressures, anthropometrics and body compositions were also measured using standard methods and bioimpedance.

Results

Men had significantly higher well-being, but lower overall self-control, impulsivity and Food Available hedonic hunger. Those with moderate/severe CD had higher odds ratio (OR) of having high central adiposity, compared with those with absent/slight CD (OR: 2.52;95% CI: 1.14, 5.61; p = 0.023 for WC and OR: 2.50; 95% CI: 1.19, 5.23; p = 0.015 for WHR). Higher CD and PFS scores were strongly significantly correlated with higher systolic blood pressure (SBP), WC, WHR, WHtR, BMI, TBF, SF, VFL and RM. Lower self-control was weakly correlated with higher WC, while lower impulsivity and restraint were weakly correlated with higher VFL. Those who were overweight, obese, and in high TBF class had significantly higher PFS Aggregate Factor scores. Food Available and Food Present scores, but not Food Tasted, were also significantly higher among overweight participants.

Conclusions

Higher hedonic hunger and CD were associated with higher SBP and all adiposity measures. Overweight participants had higher hedonic hunger in the context of ready availability and physical presence of highly palatable foods. Lower self-control was weakly correlated with higher central adiposity; lower impulsivity and restraint were weakly correlated with higher visceral adiposity. These findings have provided some insights into the cognitive factors underlying adiposity.
Oil-source correlation in the Yangjiang Uplift, South China Sea: A comparative analysis of mathematical and fingerprint methods
Authors: You Junjun , Li Hui , Lei Mingzhu , Liu Yi , Jiang Li
Published: April 2024

In recent years, significant exploration breakthroughs have been achieved in the Yangjiang Uplift. However, the source of crude oil is ambiguous, and the prevailing view suggests a remote hydrocarbon supply. To clarify the source of the crude oil in the Yangjiang Uplift, 30 source rocks and 15 crude oil samples collected from the Wenchang A Sag and Yangjiang Uplift are subjected to Rock-Eval pyrolysis, maceral analysis, vitrinite reflectance, and biomarker analysis, among other experiments. Principal component analysis and hierarchical cluster analyses are performed. The results indicate that the source rocks in the Yangjiang Uplift exhibit robust hydrocarbon-generating potential, with S1 +  S2 values ranging between 0.04 and 140.5 mg/g (averaging: 13.54 mg/g), indicative of reaching the oil generation period. Using 13 biomarker compounds, two types of biomarkers are selected to compare the sources of the crude oils: pristane/phytane (Pr/Ph) representing the depositional environment and tricyclic terpanes (TTs) representing the source input. The crude oil in the Yangjiang Uplift can be divided into two types: one with high values of bicadinane-T (T)/C30 hopane and ΣC30-4 methyl sterane/ΣC29 regular sterane and another with a low ratio of (C19TT + C20TT)/C23TT according to the charting method. The investigated crude oil is mixed with the source rocks of the Wenchang A Sag and the Yangjiang Uplift. Furthermore, owing to the differences in the mixing ratios, the crude oil in the study area exhibits two distinct characteristics. Type A is characterized by a higher proportion of the Wenchang A Sag crude oil in the mixture, whereas type B is characterized by a higher proportion of local crude oil. This study establishes that the Yangjiang Uplift boasts large petroleum resources.
Effects of Ashwagandha (Withania somnifera) standardized root extract on physical endurance and VO2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study
Authors: Verma Narsingh , Gupta Sandeep Kumar , Patil Sayali , Tiwari Shashank , Mishra Ashok Kumar
Published: April 2024

Background Ashwagandha is a well-known Ayurvedic herb used for youthful vigor and wellbeing. This study investigated the effects of 600 mg standardized root extract (>5% withanolides) of Ashwagandha (Withania somnifera) on muscle size, strength and cardiorespiratory endurance following resistance training. Methods In this eight-week, parallel-group, multicenter, randomized, double-blind, placebo-controlled clinical study, 80 healthy male and female participants aged 18-45 years, who engaged in regular physical activity were randomly allocated in a 1:1 ratio to receive Ashwagandha (AG, n=40) 300 mg capsules twice daily for eight weeks, or identical placebo (PB, n=40). Seven (3 AG, 4 PB) participants were excluded due to poor compliance. All participants conducted eight-week resistance training. Study outcomes included muscle strength (1RM bench press and leg extension), muscle size (circumference of arm, chest and upper thigh) and cardio-respiratory endurance (VO2max) assessed at baseline and at eight weeks. Analysis of covariance (ANCOVA) was used to estimate adjusted differences based on sex, BMI and chest circumference at baseline. Results AG caused greater improvement in bench press (males: p = 0.0084; females: p = 0.0005), leg press (males: p = 0.0049; females: p = 0.018) and endurance (males: p <0.0001; females: p <0.0001) as compared to PB. Also, greater improvements in muscle girth for arm, chest and thigh were seen in both male and female participants with AG. No adverse events were reported in the study. Conclusions Eight weeks of AG root extract supplementation along with resistance training is effective in improving muscle strength, growth and endurance in both male and female participants. AG root extract could be a safer, effective and low-cost alternative for athletes to improve muscle endurance.
Historia Zakładu Radiologii Pediatrycznej Warszawskiego Uniwersytetu Medycznego (część 1)
Authors: Batycki Krzysztof
Published: April 2024

Praca prezentuje historię Zakładu Radiologii Pediatrycznej Warszawskiego Uniwersytetu Medycznego, mieszczącego się w Samodzielnym Publicznym Dziecięcym Szpitalu Klinicznym przy ul. Marszałkowskiej 24 (róg ul. Litewskiej). Jedynym, obszernym opracowaniem historii Zakładu, jakie powstało do tej pory, jest bogaty w bezcenne informacje tekst profesora Andrzeja Marcińskiego, opublikowany kilkukrotnie w latach 1991-1997. Niniejsza praca w dużej mierze opiera się na nim – rozbudowano omówione już tematy, zwłaszcza o wydarzenia, które miały miejsce po jego napisaniu. Ponieważ działalność Zakładu zawsze była ściśle związana, bardziej lub mniej formalnie, z pracą Zakładu Radiologii Szpitala przy ul. Działdowskiej 1, zarys jego historii również został przedstawiony. Do napisania pracy autor wykorzystał przede wszystkim nieliczne publikacje dotyczące historii Zakładu Radiologii Pediatrycznej oraz materiały pochodzące ze zbiorów Archiwum Warszawskiego Uniwersytetu Medycznego. Całość wzbogacił o zebrany przez siebie rozległy zbiór wspomnień pracowników Zakładu i osób w inny sposób z nim związanych. Szczegółowo omówione zostało 60 lat historii  Zakładu, od jego założenia w 1951 r. do 2011 r. Zakład powstał na bazie dwóch istniejących już wcześniej pracowni rentgenowskich, dlatego pokrótce omówiona została także ich historia. Całość opracowania podzielono chronologicznie, na trzy główne części, w zależności od tego, kto pełnił funkcję kierownika Zakładu. Szczególnie obszerna część tekstu poświęcona jest ludziom tworzącym Zakład, nie tylko lekarzom – szeroko omówiona została praca techników elektroradiologów oraz zmiany, jakim jej specyfika podlegała na przestrzeni dekad.
Pułkownik doktor Władysław Gergovich (1893-1951)
Authors: Korab Michał , Mormul Agata
Published: April 2024

Pułkownik doktor Władysław Stanisław Gergovich łączył w swoim życiu dwa zawody – żołnierza i lekarza, i był wzorem poświęcenia Ojczyźnie i służbie pacjentom. W latach młodzieńczych działał w drużynach strzeleckich Józefa Piłsudskiego, a po wybuchu I wojny światowej służył w Legionach Polskich. W dwudziestoleciu międzywojennym pracował jako lekarz wojskowy oraz prowadził działalność dydaktyczną – przygotowywał przyszłych oficerów-lekarzy do pracy w czasie wojny. Kampanię wrześniową odbył na stanowisku szefa sanitarnego Armii „Kraków”. Po kapitulacji armii pod Tomaszowem Lubelskim stworzył na Zamojszczyźnie wielkie centrum szpitalne, w którym pomocy medycznej udzielono setkom rannych polskich żołnierzy. Po wydostaniu się z okupowanego kraju Gergovich działalność tę kontynuował we Francji i w Anglii, m.in. na stanowisku Szefa Służby Zdrowia Sztabu Naczelnego Wodza. Przedstawiając zarys biografii pułkownika, starano się uwypuklić przede wszystkim wojenny fragment jego działalności lekarskiej.
Análisis institucional de la implementación articulada de la agenda 2030 y el acuerdo de París en Colombia
Authors: Restrepo Medina Manuel Alberto
Published: April 2024

El objeto del presente capítulo consiste en exponer el diseño institucional adoptado por el Estado colombiano para la implementación y monitoreo tanto de la Agenda 2030 y sus ODS como del Acuerdo de París y establecer si el mismo permite que ello se haga de manera integrada entre ambas agendas de desarrollo.
Liquidity Risk and Currency Premia
Authors: Söderlind Paul , Somogyi Fabricius
Published: April 2024

The currency market is the world’s largest financial market by trading volume. We show that even in this highly liquid market, exposure to liquidity risk commands an economically significant risk premium of up to 3.6% per year. Liquidity risk is not subsumed by existing currency risk factors and successfully prices the cross section of currency excess returns. Moreover, we find that liquidity risk and carry trade premia are correlated, although this correlation is limited to static rather than dynamic carry trades. Building on this result, we propose a liquidity-based explanation for the carry trade, which adds significant explanatory power to existing theories.

This paper was accepted by Lukas Schmid, finance.

Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2023.01031 .
On Constrained Mixed-Integer DR-Submodular Minimization
Authors: Yu Qimeng , Küçükyavuz Simge
Published: April 2024

Diminishing returns (DR)–submodular functions encompass a broad class of functions that are generally nonconvex and nonconcave. We study the problem of minimizing any DR-submodular function with continuous and general integer variables under box constraints and, possibly, additional monotonicity constraints. We propose valid linear inequalities for the epigraph of any DR-submodular function under the constraints. We further provide the complete convex hull of such an epigraph, which, surprisingly, turns out to be polyhedral. We propose a polynomial-time exact separation algorithm for our proposed valid inequalities with which we first establish the polynomial-time solvability of this class of mixed-integer nonlinear optimization problems.

Funding: This work was supported by the Office of Naval Research Global [Grant N00014-22-1-2602].
Sequência didática baseada no ensino investigativo para educação de jovens e adultos utilizando tecnologias de comunicação e informação no ensino de física
Authors: Vieira Isabela Felix Elizio , Ribeiro Moisés Medrado , De Castro Robson Costa , Canellas Catarine Gondim Leitão
Published: April 2024

A Educação de Jovens e Adultos (EJA), no Brasil, por vezes, é prejudicada, pela falta de investimento em pesquisa e pelas dificuldades estruturais. Além disso, se tratando do ensino de Física, os estudantes da EJA ainda precisam lidar com o nível abstração dos conceitos físicos e as limitações das metodologias de ensino tradicionais que dificultam o processo de ensino aprendizagem, colaborando para a evasão escolar. De acordo com o modelo de educação integral e inclusiva presente na Base Nacional Comum Curricular (BNCC), foi aplicada em turmas da EJA uma Sequência de Ensino Investigativo (SEI), que atende às exigências da BNCC, baseada em dois dos principais apontamentos desse documento para o ensino de Ciências da Natureza: o método de ensino por investigação e a utilização de dispositivos e tecnologias digitais de informação e comunicação (TDIC). Foram realizadas três aulas com 1h20min cada para aplicação da SEI e todas foram iniciadas com questionamentos aos alunos sobre alguns conteúdos relacionados ao Eletromagnetismo. No decorrer das discussões, vídeos educacionais e simulações foram utilizados pelos licenciandos oportunizando a interação dos estudantes com as ferramentas digitais a fim de facilitar a compreensão dos conceitos abordados. A aprendizagem dos alunos foi analisada com base em uma avaliação formativa e por meio de um questionário com perguntas objetivas e autoavaliativas. A utilização da SEI foi importante para a estruturação das aulas na EJA porque auxiliou os alunos em seu processo de ensino-aprendizagem tornando o ensino de Física mais acessível e inclusivo.
Avaliação da aprendizagem de conceitos de cinemática e dinâmica através da produção de histórias em quadrinhos
Authors: Vilar Artur Batista , Pereira Felipe de Carvalho , Rinaldi Bruno Bernardo
Published: April 2024

Buscamos, com este artigo, analisar a possibilidade de utilização de histórias em quadrinhos (HQs) e tirinhas no processo de avaliação da aprendizagem de conceitos de física, com destaque para os tópicos de cinemática e dinâmica do ensino médio. Almejamos, ainda, contribuir para um processo de ensino-aprendizagem em física que valorize a integração entre a ciência e a arte e que seja mais lúdico, motivador e conectado às experiências cotidianas dos estudantes da educação básica. Para tal, nos baseamos em trabalhos e publicações sobre a utilização de HQs no ensino de Ciências e em uma intervenção pedagógica em que os estudantes de turmas do ensino médio técnico integrado de um Instituto Federal de Educação, Ciência e Tecnologia foram estimulados a produzir tirinhas e quadrinhos autorais com temáticas inspiradas nos conteúdos abordados durante as aulas de física realizadas em um formato remoto, decorrente do cenário estabelecido pela pandemia de Covid-19. Pretendemos demonstrar que essas ferramentas podem ser aplicadas em quaisquer outras temáticas da física e analisamos, por fim, a contribuição da inserção do campo da CienciArte no processo de avaliação da aprendizagem dos estudantes, assim como da prática docente aplicada.
Reflexões Teóricas sobre a Interdisciplinaridade na Pesquisa em Ensino de Física: da Epistemologia Genética de Piaget à interação com a Educação em Direitos Humanos
Authors: Queiroz Gloria Regina Pessoa Campello
Published: April 2024

As reflexões teóricas apresentadas nesse artigo trazem elementos da história profissional de componentes de um Grupo de Pesquisa em Ensino de Ciências nos últimos quarenta anos, no que diz respeito ao direcionamento construtivista que incorporou os direitos humanos ao ensino, à pesquisa e à extensão nos temas abordados. Nessa trajetória destacamos a presença interdisciplinar entre o Ensino das Ciências da Natureza – Física, Química e Biologia, com outras áreas, inicialmente a Psicologia, a História, a Filosofia, a Pedagogia a Epistemologia, e mais recentemente acrescentando interações dialógicas com a Linguística, a Natureza da Ciência e a Educação em Direitos Humanos.
Assim falava Beatriz Alvarenga sobre laboratório há 33 anos
Authors: Vianna Deise M.
Published: April 2024

Este artigo tem como principal objetivo reeditar a palestra escrita por Beatriz Alvarenga, em 1990, logo após a 1ª Escola de Verão para Licenciandos que foi organizada pela Secretaria Regional Rio da Sociedade Brasileira de Física. Estes escritos relatam, além de suas atividades naquele evento, suas ideias a respeito do ensino de física, principalmente do ensino experimental que apesar de ter sido escrito em 1990 ainda é bastante atual, 33 anos depois. Deixar esta palestra de Beatriz à disposição daqueles que não a conheceram pessoalmente é uma contribuição bastante importante para inflamar as discussões sobre o ensino de física no país e estimular professores a dedicarem-se ao ensino, principalmente experimental, de física. Este escrito o encontrei em uma pesquisa por referências para elaborar outros trabalhos referentes à formação de professores que deveriam ser apresentados em eventos a serem realizados em Brasília, DF. O escrito aqui apresentado, além de um histórico das aulas experimentais no país traz uma forte contribuição para exaltar os jovens licenciandos e os já licenciados a continuarem firmes na profissão. Como considerações finais apresentarei uma discussão dos pontos que julguei mais relevantes em suas palavras.
O Mestrado Nacional Profissional em Ensino de Física na região Norte do Brasil
Authors: Santos Bianca Martins , Vianna Deise Miranda
Published: April 2024

O trabalho apresenta o perfil dos docentes do Mestrado Nacional Profissional em Ensino de Física (MNPEF) que atuam na região Norte do Brasil quanto à área de formação, sexo, produção acadêmica, atualização do CV (Curriculum Vitae) Lattes e o quantitativo de egressos em nível de pós-graduação da mesma instituição que abriga o polo. Para esta análise qualitativa e quantitativa, foi consultada a listagem do corpo docente nos sites dos 11 polos e paralelamente o CV na Plataforma Lattes dos 126 docentes que atuam no mestrado na região Norte. Comenta-se paralelamente o quantitativo de pós-graduação na região Norte do Brasil e a situação desarmoniosa desta em relação ao restante do país. Ao final são traçadas algumas reflexões sobre os resultados encontrados, ressaltando a importância de o MNPEF ter chegado a todos os estados da região Norte, estabelecendo um diálogo entre os dados encontrados com a realidade particular da região.
Ensinar Química através dos Poemas de Primo Levi
Authors: Costa Natália Matos Sanglar
Published: April 2024

Primo Levi, italiano, judeu e químico, sofreu os horrores do holocausto durante a segunda guerra mundial, ficando cerca de onze meses nos campos de concentração de Auschwitz. Essa experiência o motivou a se tornar escritor, produzindo poemas, contos, romances e ensaios. Suas primeiras obras foram: É isto um homem?, A trégua e Os afogados e os sobreviventes. Ele também escreveu A tabela periódica, livro que marca sua identidade como químico e tem um caráter autobiográfico. Neste artigo, três poemas do autor, presentes na coletânea Mil sóis, são analisados, buscando identificar conteúdos de química. Essa investigação é feita através da análise do discurso, considerando a perspectiva do dialogismo de Bakhtin. Os textos A obra, Um vale e o degelo, selecionados para essa análise, revelam a sensibilidade do autor e ao mesmo tempo o seu senso crítico. Os conceitos de química encontrados nesses poemas são: metais, ligação de hidrogênio e tensão superficial, em A obra; características da resina e conceito de temperatura, em Um vale; e separação de misturas, oxirredução e mudança de fase, em O degelo. Esses temas permitem pensar no uso desses poemas em sala de aula para o Ensino de Química, possibilitando uma abordagem social, interdisciplinar e contextualizada.
HISTÓRIAS DE VIDA NO CURRÍCULO:
Authors: Lopes Luís Fernando , Lisboa Edson da Silva Rodrigues , Silva Nádia Cataryna Nogueira e
Published: April 2024

Apresenta-se uma análise de autores das ementas numa perspectiva intercultural. Parte-se da problemática de que o currículo é reflexo social e, por isso, pode tender à exclusão. Considera-se que em sala de aula, muitas vezes, as obras utilizadas são descontextualizadas da subjetividade dos autores, ou seja, sem que o estudante saiba quem são e por que decidiram se envolver com tal temática. Assim, a hipótese é que fazendo uso das histórias de vida dos autores, haverá mais afetividade e maior propensão à diminuição da desigualdade social. Objetiva-se apresentar alguns autores elencados nas referências básicas das ementas das disciplinas dos cursos de graduação em Filosofia de cinco universidades federais. Fundamenta-se nas concepções de emancipação em Freire (1996); história de vida em Bertaux (2010); afetividade em Wallon (1995); e currículo em Sacristàn (2000). A metodologia é qualitativa e exploratória. Os resultados permitem interpretar que o uso de histórias de vida de autores possibilita espaços facilitadores para a equidade social.
ARTIVISMOS FEMINISTAS E EDUCAÇÃO
Authors: Lima Indiara Launa Teodoro da Silva , Souza Ana Paula Abrahamian de
Published: April 2024

Este artigo apresenta uma análise da produção acadêmico-científica sobre as relações entre artivismos feministas e educação. Tendo como recorte o período de 2018 a 2023, analisa-se sob uma abordagem qualitativa pós-crítica, mapeando os campos teórico-metodológicos, aspectos investigativos e resultados mais representativos das publicações. Foram identificadas dez publicações no acervo da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD), utilizando os seguintes descritores: artivismo, feminismo, educação popular e educação. A emergência de estudos sobre as expressões artivistas feministas nos últimos anos, e a ausência relevante de maiores trabalhos que explicitem a relação destas práticas com a educação, é uma das principais constatações evidenciadas pela análise de pesquisa bibliográfica. Dentro das diversas dimensões, que abrangem as discussões nos estudos, as mais relevantes aparecem sob a luz das teorias pós-estruturalistas, queer, decoloniais e em formulações sobre os lugares educativos dos artivismos, que variam entre a educação não-formal e a pedagogia feminista.
Establishment of a hospital group complaints staff network
Authors: Kenny Orla
Published: April 2024

This article describes the rationale and development of a complaints staff network in a hospital group in Ireland. The network was set up in early 2022 to encourage standardisation in healthcare complaints management and provide a platform for shared learning for staff directly involved in complaints management. Staff who handle complaints, either as their full-time role or as part of their role, have shown willingness to engage in the network and use it to access support. Membership of the network has more than doubled since its inception. This novel approach to sharing learning in complaints management at hospital-group level could be adopted in other healthcare organisations.