bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PENGUATAN OTOT TRANSVERSUS ABDOMINIS TERHADAP NYERI MENSTRUASI PADA MAHASISWA KEBIDANAN UNIVERSITAS AISYIYAH YOGYAKARTA
Authors: Fitriahadi Enny , Daryanti Menik Sri , Sulistyanigsih Sulistyanigsih
Published: September 2017

Dismenore merupakan nyeri yang dialami remaja saat menstrusi. Dismenore disebabkan ketidakseimbangan hormon progesteron dalam darah, prostaglandin dan faktor stress/psikologi mengakibatkan terjadinya dismenore pada beberapa wanita. Nyeri haid sering dialami oleh sebagian besar wanita. Dari data yang didapat, dismenore ini mengganggu setidaknya 50% wanita masa reproduksi dan 60-85% pada usia remaja, yang mengakibatkan banyaknya absensi pada sekolah maupun kantor. Untuk mengatasi hal tersebut sebagian wanita menggunakan obat yang berfungsi secara kuratif. Dalam penelitian akan memberikan alternatif terapi yang sederhana, mudah dilakukan dan bersifat preventif. Penelitian kuantitatif ini bertujuan untuk mengetahui pengaruh penguatan otot transversus abdominis terhadap nyeri menstruasi pada mahasiwi kebidanan Universitas Aisyiyah Yogyakarta. Subyek penelitian ini adalah mahasiswi Universitas Aisyiyah Yogyakarta. Teknik pengambilan sampel yang akan digunakan adalah purposive sampling. Instrumen yang digunakan untuk mengukur nyeri menstruasi adalah skala nyeri menurut wong baker face dan lembar pemantauan sebelum dan sesudah dilakukan intervensi. Analisa data yang digunakan adalah menggunakan rumus paired sample t test. Hasil penelitian ini berdasarkan analisis paired sample test di dapatkan bahwa asymp sig. (2-tailed) 0,000 < a = 0,05, sehingga disimpulkan terdapat pengaruh yang signifikan antara penguatan otot transversus abdominis terhadap penurunan nyeri menstruasi. Saran bagi mahasiswi kebidanan Universitas Aisyiyah Yogyakarta supaya dapat mempraktekkan secara langsung teknik pengurangan nyeri menstruasi dengan penguatan otot transversus abdominis.
FAKTOR RISIKO MATERNAL KEJADIAN ABORTUS (Studi Kasus di RSUD Dr. Soeselo Slawi Kabupaten Tegal)
Authors: Fatkhiyah Natiqotul , Kodijah Kodijah , Hadiningsih Tri Agustina
Published: September 2017

Latar Belakang: Abortus spontan yang disertai terjadinya perdarahan dapat menyebabkan sebagian placental site masih terbuka sehingga perdarahan terus berlangsung. Pasien dapat jatuh dalam keadaan anemia atau syok hemoragik sebelum sisa jaringan konsepsi dikeluarkan. Tujuan penelitian: Untuk mengetahui hubungan faktor risiko maternal dengan kejadian abortus spontan di RSUD dr. Soeselo Kabupaten Tegal. Metode: jenis penelitian kuantitatif dengan pendekatan cross sectional. Analisis data dilakukan secara univariat dan bivariat dengan chi square. Hasil: ibu yang mengalami abortus 50% (20 responden) dan persalinan spontan 50% (20 ibu). Berdasarkan usia, 75% responden (30 ibu) dengan umur berisiko (usia <20tahun dan >35 tahun) dan 25 % (10 ibu) dengan usia reproduksi sehat (usia 20-35 tahun). Berdasarkan paritas, ibu dengan paritas aman (persalinan pertama sampai keempat) sebesar 62,5% (25 ibu) dan paritas berisiko (belum pernah melahirkan atau ≥ 5 kali partus) sebesar 37.5% (15 ibu). Ada hubungan umur ibu dengan kejadian abortus (p value=0.03) dan tidak ada hubungan paritas dengan kejadian abortus (p value=0.327).
Implementation of Reseptive Esteemy Approach Model in Learning Reading Literature
Authors: Nurhayatin Titin
Published: September 2017

Research on the implementation of aesthetic model of receptive aesthetic approach in learning to read the literature on the background of the low quality of results and learning process of Indonesian language, especially the study of literature. Students as prospective teachers of Indonesian language are expected to have the ability to speak, have literature, and their learning in a balanced manner in accordance with the curriculum demands. This study examines the effectiveness, quality, acceptability, and sustainability of the aesthetic approach of receptions in improving students' literary skills. Based on these problems, this study is expected to produce a learning model that contributes high in improving the quality of results and the process of learning literature. This research was conducted on the students of Language Education Program, Indonesian Literature and Regional FKIP Pasundan University. The research method used is experiment with randomized type pretest-posttest control group design. Based on preliminary and final test data obtained in the experimental class the average preliminary test was 55.86 and the average final test was 76.75. From the preliminary test data in the control class the average score was 55.07 and the average final test was 68.76. These data suggest that there is a greater increase in grades in the experimental class using the aesthetic approach of the reception compared with the increase in values in the control class using a conventional approach. The results show that the aesthetic approach of receptions is more effective than the conventional approach in literary reading. Based on observations, acceptance, and views of sustainability, the aesthetic approach of receptions in literary learning is expected to be an alternative and solution in overcoming the problems of literary learning and improving the quality of Indonesian learning outcomes and learning process.
Implementation of Reciprocal Teaching Models to Increase The Capability of Writing Definition and Theorem in Simbolic Form
Authors: T Ahmad Yani , Lanteri Cristina
Published: September 2017

This study aims to obtain objective information about increasing in writing skill about definitions and theorems in symbolic form students through RT models in the sets, all kind of relations and functions in set and logic courses. In addition, this study develop the ability of understanding of definitions and theorems, because the ability of students to write definitions and theorems in symbolic form will foster the ability of understanding of the definitions and theorems.The sample of this study are the first semester students in class A2 who follow sets and logic  course in mathematics education program of PMIPA FKIP Untan 2016-2017. Implementation focus on subject, sets and all kind of relations and functions.The data collection conducted in providing achievement test after being given treatment. Form of test is Essai with 15 questions which consist of  4 questions from subject set, 8 questions from kind of relations and 3 questions from functions.The results showed if the Reciprocal Teaching Model is one of model that could improve the writing skill about definitions and theorems through symbolic form in the subject matter ; Sets, kind of relations, functions in Sets and Logic courses.
The psychological distress and psychic phenomena in cancer patients during palliative care
Authors: Mukharovska Inna
Published: September 2017

Background

The diagnostic cancer in incurable stages, the transition to palliative care because of disease progression are significant psychological challenge for the patient. Psychological help for cancer patients during palliative treatment are no less important than medical therapy.

Methods

The study conducted at the Kyiv City Clinical Cancer Center during the 2012 - 2013 years in two phases. In first phase provided psychological investigation psychological condition of incurable cancer patients and its dynamics during palliative therapy with followed qualitative analysis of the data – participated 436 patients. Second phase included determining factors of psychological maladjustment and evaluation intensity of mental distress – participated 63 palliative cancer patients. The SCL-90r used for assessment of psychic distress.

Results

The prominent psychopathological symptoms in incurable cancer patients were somatization, depression and nonspecific symptoms. Less pronounced signs of mental distress in descending order of severity were anxiety, hostility, paranoid ideation, interpersonal sensitivity, obsessive-compulsive, psychoticism and phobic anxiety. Factors of psychological distress in cancer patients during palliative care include high physical distress; the impossibility of total control on physical and psychological symptoms; chronic pain; progressive deterioration of physical well-being; need to use opioids for relief pain; need for help; existential nature of stress; individual psychological characteristics. In patients identified psychological phenomena related to the palliative phase of treatment: psychological induction "pendulum", externalizing of mental stress, decentralization.

Conclusion

Cancer patients in the palliative stage of treatment experiencing intensive psychological distress and clinically constitute a special group with specific psychological needs, which need to be consider in providing psychological care.
Сognitive-behavioral therapy in generalized anxiety disorder
Authors: Burda Hanna
Published: September 2017

Generalized anxiety disorder - is a common disease, which is quite difficult diagnosed and treated. Cognitive-behavioral therapy is indicated to patients with GAD as a first-line method. This article provides an overview of the principles, advantages and evidence of the effectiveness of this type of therapy. Although cognitive behavioral therapy has advantage over other types of therapy for GAD, this issue requires further research, because there are problems such as a high percentage of patients interrupting therapy and relatively low percentage of clinically meaningful improvement.
Pharmacotherapy versus psychological interventions in recurrent abdominal pain: in light of new evidence
Authors: Bezsheiko Vitaliy
Published: September 2017

Chronic or recurrent abdominal pain is a relevant problem, which affects more than 15% of children, adolescents and young people. Organic reason for this pain can't be found in most cases. Recently published studies have questioned the traditional treatment schema with prescribing antispasmodics, antidepressants and other traditional drugs and shifted focus towards psychological interventions.
Evaluation of the evoked brain potentials of patients with asthenia and anxiety symptoms and the partial loss of sight
Authors: Abdryakhimova Tsira , Abdryakhimov Rostislav , Snegir Andriy , Kleban Katherine , Mukharovska Inna
Published: September 2017

Background

Loss of sight, even partial, especially in adulthood, is accompanied by emotional, motivational and social consequences that directly affect the psychophysiological state of the individual himself, his communication in society and, often, the social status of the subject.

Methods

From the group of patients-volunteers (n=15) with a partial loss of sight of traumatic genesis two groups were formed for carrying out neurophysiological studies: with predominant asthenia and predominant anxiety. The controle group (CG) constisted from patients of the same age (n=20) without psychiatric comorbidity. A study of acoustic event-related potentials of the brain (ERP) was carried out in the oddball paradigm with the recording of the time and correctness of a simple sensorimotor reaction.

Results

Comparative analysis of the asthenia group with the comparison group revealed a sufficient number of indicators of the ERP, which have significant statistical differences. The correctness of the sensorimotor reaction in this group was 98.3 ± 2.44%, whereas in the CG - 92.5 ± 5.74% (U = 62.5, p <0.01). The values of the amplitude of the early positivity of P1 in the asthenia group were 4.25 ± 3.312 μV, and in the CG -4.15 ± 7.933 μV (U = 50, p <0.001). The early negativity in that group was -2.78 ± 2.377 μV, and in the CG it was 10.55 ± 7.466 μV (U = 75; p <0.05).

Conclusion

In the asthenia group this is the correctness of the sensorimotor reaction and the amplitude of the components: P1, N1, P2, N2. In the anxiety group, such indicators were: latency period P1, intervals P1N1 and N2P3, amplitude swing P1N1. A specific marker of the asthenia group, distinguishing it from the CG, was the more positive values of the amplitude of the components P1, N1, P2, N2. Taking into account the low-frequency nature of the modulation of the amplitudes of these components (circa 2 Hz), it can be assumed that nonspecific brainstem systems are involved in the process.
Dependence of the constitution, microstructure and electrochemical behaviour of magnetron sputtered Li–Ni–Mn–Co–O thin film cathodes for lithium-ion batteries on the working gas pressure and annealing conditions
Authors: Strafela Marc , Fischer Julian , Music Denis , Chang Keke , Schneider Jochen , Leiste Harald , Rinke Monika , Bergfeldt Thomas , Seifert Hans Jürgen , Ulrich Sven
Published: September 2017

Li(Ni1/3Mn1/3Co1/3)O2as a cathode material for lithium ion batteries shows good thermal stability, high reversible capacity (290 mAh g−1), good rate capability and better results in terms of environmental friendliness. In this paper thin film cathodes in the material system Li–Ni–Mn–Co–O were deposited onto silicon and stainless steel substrates, by non-reactive r.f. magnetron sputtering from a ceramic Li1.18(Ni0.39Mn0.19Co0.35)O1.97target at various argon working gas pressures between 0.2 Pa and 20 Pa. A comprehensive study on the composition and microstructure was carried out. The results showed that the elemental composition varies depending on argon working gas pressure. The elemental composition was determined by inductively coupled plasma optical emission spectroscopy in combination with carrier gas hot extraction. The films showed different grain orientations depending argon working gas pressures. The degree of cation order in the lattice structure of the films deposited at 0.5 Pa and 7 Pa argon working gas pressure, was increased by annealing in an argon/oxygen atmosphere at different pressures for one hour. The microstructure of the films varies with annealing gas pressure and is characterized using X-ray diffraction and unpolarized micro-Raman spectroscopy at room temperature. Electrochemical characterization of as-deposited and annealed films was carried out by galvanostatic cycling in Li–Ni–Mn–Co–O half-cells against metallic lithium. Correlations between process parameters, constitution, microstructure and electrochemical behaviour are discussed in detail.
Empowering patients and community online: Evaluation of the AIDS community information outreach program
Authors: Dancy Nicole C. , Rockoff Maxine L. , Dutcher Gale A. , Keselman Alla , Schnall Rebecca , Siegel Elliot R. , Bakken Suzanne
Published: September 2017

The AIDS Community Information Outreach Program (ACIOP) was created in 1994 to assist the affected community in utilizing electronic HIV/AIDS information resources. Nearly 300 competitive awards have been made to mostly community-based organizations. A formal evaluation was undertaken to determine the performance and impact of the ACIOP. A mixed methods design combined quantitative abstractions and summarization of 47 awardee final reports from 44 organizations, and qualitative telephone interviews with 17 individuals representing 20 projects. Findings revealed that project objectives were mostly met; high-risk populations were reached; low resource organizations were funded; community partnerships were significant; projects built on existing efforts; information resources and training were tailored to local needs; and most projects overcame barriers experienced. Needed modifications centered on: (1) enhancing evaluation capacity at the individual project level and (2) revising project reporting requirements to increase the amount of information available to assess the ACIOP; both have been implemented.
Re-envisioning the business of information: Policies, practices and procedures
Authors: Kenneally Christopher , Ivins October , Martone Maryann , Mueller Britt , Trippe William
Published: September 2017

Re-envisioning the business of information does not stop with new product development, new production infrastructures, and new financial business models. It requires an alignment of business policies with the changing needs and expectations of the information users. Publishers and librarians must develop the policies, practices, and procedures that will facilitate – not inhibit – the use of their information and maximize its value to the user. This requires that both communities move beyond the comfort zone of their current practices, policies, biases and business mindsets. This interactive panel discussion was organized to take a look at some of the issues that concern content providers and librarians as the new information mindset takes hold, such as the re-use, replication and sharing of data, privacy, content ownership, attribution and others.
Identifying user behavior in domain-specific repositories
Authors: van Hoek Wilko , Shen Wei , Mayr Philipp
Published: September 2017

This paper presents an analysis of the user behavior of two different domain-specific repositories. The web analytic tool etracker was used to gain a first overall insight into the user behavior of these repositories. Moreover, we extended our work to describe an apache web log analysis approach which focuses on the identification of the user behavior. Therefore the user traffic within our systems is visualized using chord diagrams. We could find that recommendations are used frequently and users do rarely combine searching with faceting or filtering.
EPISCIENCES – An overlay publication platform
Authors: Berthaud Christine , Capelli Laurent , Gustedt Jens , Kirchner Claude , Loiseau Kevin , Magron Agnès , Medves Maud , Monteil Alain , Rivrieux Gaëlle , Romary Laurent
Published: September 2017

This paper delineates the main characteristics of the Episciences platform, an environment for overlay peer-reviewing that complements existing publication repositories, designed by the Centre pour la Communication Scientifique directe (CCSD) service unit. We describe the main characteristics of the platform and present the first experiment of launching two journals in the computer science domain onto it. Finally, we address a series of open questions related to the actual changes in editorial models (open submission, open peer-review, augmented publication) that such a platform is likely to raise, as well as some hints as to the underlying business model.
Shared service components infrastructure for enriching the user experience in electronic publications
Authors: Houssos Nikos , Stathopoulos Panagiotis , Stathopoulou Ioanna-Ourania , Kalaitzis Andreas , Soumplis Alexandros
Published: September 2017

A major requirement for electronic publishing systems is the availability of rich and intuitive mechanisms that enhance the user experience of viewing and searching online electronic documents such as books, monographs and journal papers. This work concerns a set of infrastructural components and their utilization for the creation of related coherent services and features for end users. We present a set of sophisticated platforms, tools and mechanisms that have been employed in real-life cases for implementing document viewing and full-text search features, shared among application instances of various types. Challenges encountered and the provided solutions are discussed.
EKT ePublishing: Developing an Open Access publishing service for the Greek research community
Authors: Nafpliotis Alexandros , Tsoukala Victoria , Houssos Nikos , Kalaitzis Andreas , Sachini Evi
Published: September 2017

The present contribution concerns a case study of open access scholarly publishing in Greece, its history and effect in helping the local researcher community transition from a print-only mode of work to online working environments and in rendering Greek publications and scholarship more relevant to the international scholarly community. The paper elaborates on the goals of the project and the challenges that were encountered and addressed during its implementation. The project, which started in 2007 with the transition of three print journals in the humanities to an online and print format and online working environment, culminated in the development of an online platform that provides access to content and services from a single point in the web, ePublishing.ekt.gr. As part of the National Documentation Centre (EKT)'s services, we systematize and upgrade the journals' policies according to international standards, provide an online working platform and training, digitize and release in open access academic articles (more than 3,500 articles in established journals, published by small, non-profit, academic/scholarly society publishers, so far), provide DOIs, as well as concentrate on electronic books and conference proceedings – also to include purely online books in the future, starting with a born-digital monograph in a Humanities subject (onlineBook). In a nutshell, we have focused on providing publishers of scientific journals a range of comprehensive services which are constantly updated and improved in the light of the developments in scholarly communication, and which foster the internationalization, visibility, and preservation of research in these fields.
A new paradigm for the scientific article
Authors: Weilenmann Anne-Katharina
Published: September 2017

Information overload is a great problem for the scientific community. To deal with the abundance of new scientific articles there are methods of sophisticated information retrieval tools and text mining tools. Little is known about the relationship between document structure and the structure of thought. This paper describes a project in this matter.
Transforming a research paper into a rich internet publication
Authors: Breure Leen
Published: September 2017

Scientific communication is gradually changing. In the web era the genre of the printed paper has survived in digital format as static PDF, but annotations, multimedia and access to data are appearing as new interactive features of innovative scholarly journals. Together they justify the term Rich Internet Publication (RIP) as name for a new emerging genre. Because of the authoritative role of publications in highly ranked journals, a RIP is mostly used as a ‘showcase’ to publish supplementary material that could not be made available otherwise, and to generate a broader interest in a project. The traditional authoring of linear text does not adequately fit the new situation, in which the author has to deal with much more information in various formats and has access to new options for presentation. This paper describes a strategy to transform a regular paper into a RIP. The strategy is divided into a conceptual stage, in which focal points are created and a balanced mixture of different media are achieved divided over different levels, and the implementation.
The information seeking behaviour of nurses in the UK
Authors: Wakeham Maurice
Published: September 2017

Little has been written about the information needs and information seeking behaviour of nurses. The British Library funded project described here has sought to identify the kinds of information sought by nurses and student nurses; their use of libraries was investigated. The study found that nurses most often need information in relation to patient or client care and for their own personal interest. They are least interested in information that relates to new courses or jobs or in preparing for interviews for them. An individual's own journals and their nursing colleagues are the main sources of information. Libraries were found to be relatively little used except when research or coursework were being undertaken. Asking the librarian and browsing the shelves were the most common ways of finding information in the library. Changes in nursing education imply an expanding role for nursing libraries which they are at present ill equipped to satisfy.
Opportunities for CD-ROM information services in Africa
Authors: Compton Anne W.
Published: September 2017

In Africa, the primary audience for CD-ROM consists of the almost 1,000 national, higher education, and special libraries in the region. Several studies show that microcomputers already exist in many African libraries, with PC capability in the region growing very rapidly. A 1991 UNESCO survey reports 11% of African library respondents already have CD-ROM drives, an AAAS survey reports 15%, and the POPLINE project is currently supporting 71 organizations that have CD-ROM drives. CD-ROM alleviates many information transfer problems in Africa and has been accepted rapidly by information intermediaries, but producers/publishers should be aware of the unique marketing problems in the region.
World-wide access to computer models of biological systems
Authors: Wastney M.E. , Broering N. , Ramberg C.F.R. , Zech L.A. , Canolty N. , Boston R.C.
Published: September 2017

Models are used to study complex biological systems to represent hypotheses, test theories, make predictions, design outcomes, and analyze data. Because models coalesce a large amount of information they form valuable tools in research and education. However, their utility resides in being able to use and manipulate them interactively. Currently, there is no centralized way to access published models in order to use them. This paper describes the need and an approach for establishing such a facility, called a model library. Models will be collated, indexed, catalogued, described mathematically in formats compatible with several widely-used modeling software packages, and made available on the Internet. Users will be able to locate and view graphical and mathematical descriptions of the models and to download models to use with their own modeling software. This task will be accomplished by scientists with expertise in the fields of information science, library science, biology, modeling, computer science, and networking.
A users' perspective on information services
Authors: van de Wijngaert Lidwien
Published: September 2017

The use of information services proved to be hard to predict. This can be accounted for as a consequence of the false assumption that media use can be explained by looking from a suppliers perspective. This has been done frequently over the last decades. In communication theory we do find media use explained. Here a users' perspective is maintained. However, available theories only apply to traditional mass media. Accordingly, also from a theoretical perspective it is hard to explain the use of information services. The goal of this article is to contribute to the explanation of the use of information services by taking a users' perspective. The conclusion of this article is that the key areas for learning are accessibility, interactivity, content and the context in which communication takes place, both with regard to practice as well as theory.
Trans-European telecommunication networks: towards global interoperability
Authors: Turner Colin
Published: September 2017

The EU has initiated a programme for the development of advanced telecommunications networks within the EU. A vital part of the development of these networks is that they achieve interoperability with other emerging advanced networks. Such interoperability is important in terms of pushing forward the information society. However, the development of an all embracing network environment still faces considerable hurdles.
Supporting organisational learning: an overview of the ENRICH approach
Authors: Mulholland Paul , Domingue John , Zdrahal Zdenek , Hatala Marek
Published: September 2017

Traditional training separates learning from the work context in which the newly acquired knowledge is to be applied. This requires the worker themselves to apply imparted theoretical knowledge to knowledge in practice, a process that is grossly inefficient. The ENRICH approach builds on organisational learning theory to intertwine working and learning. The ENRICH methodology incorporates theories of learning at the individual, group and organisational level. Individual level learning is supported through the provision of semantically related resources to support problem reframing and to challenge assumptions. Group learning is supported through the evolution of domain concepts through work documents and representations linked to formal models of group knowledge, and the development of group practices and perspectives through enhanced sharing and collaboration. Organisational learning is supported through exposure to customs and conventions of other groups through shared best practices and knowledge models. The approach is being investigated in a range of industrial settings and applications.
The record of experimental science: Archiving data with literature
Authors: Helliwell John R. , McMahon Brian
Published: September 2017

Crystallography is presented as a case study of a scientific discipline where the experimental data that underpin research results can be integrated into the scientific record. Among other advantages, this maximises the degree of trust in science, since published results can thereby always be validated independently.
The anatomy of a nanopublication
Authors: Groth Paul , Gibson Andrew , Velterop Jan
Published: September 2017

As the amount of scholarly communication increases, it is increasingly difficult for specific core scientific statements to be found, connected and curated. Additionally, the redundancy of these statements in multiple fora makes it difficult to determine attribution, quality and provenance. To tackle these challenges, the Concept Web Alliance has promoted the notion of nanopublications (core scientific statements with associated context). In this document, we present a model of nanopublications along with a Named Graph/RDF serialization of the model. Importantly, the serialization is defined completely using already existing community-developed technologies. Finally, we discuss the importance of aggregating nanopublications and the role that the Concept Wiki plays in facilitating it.
Relationship between Commonly Used Adsorption Isotherm Equations Impedes Isotherm Selection
Authors: Dorkó Zsanett , Szakolczai Anett , Tóth Blanka , Horvai George
Published: September 2017

If the measured isotherm data of an adsorption system are well described by the Freundlich equation, then they can similarly well be described by the bi-Langmuir or tri-Langmuir model in most practical cases. This is proved by Monte Carlo simulation and by comparison of the mathematical functions of the respective isotherm models.
Structural Dynamics of Spin Crossover in Iron(II) Complexes with Extended-Tripod Ligands
Authors: Stock Philipp , Wiedemann Dennis , Petzold Holm , Hörner Gerald
Published: September 2017

Selective manipulation of spin states in iron(II) complexes by thermal or photonic energy is a desirable goal in the context of developing molecular functional materials. As dynamic spin-state equilibration in isolated iron(II) complexes typically limits the lifetime of a given spin state to nanoseconds, synthetic strategies need to be developed that aim at inhibited relaxation. Herein we show that modulation of the reaction coordinate through careful selection of the ligand can indeed massively slow down dynamic exchange. Detailed structural analysis of [FeL]2+ and [ZnL]2+ (L: tris(1-methyl-2-{[pyridin-2-yl]-methylene}hydrazinyl)phosphane sulfide) with crystallographic and computational methods clearly reveals a unique trigonal-directing effect of the extended-tripod ligand L during spin crossover, which superimposes the ubiquitous [FeN6] breathing with trigonal torsion, akin to the archetypal Bailar twist. As a consequence of the diverging reaction coordinates in [FeL]2+ and in the tren-derived complex [Fe(tren)py3]2+, their thermal barriers differ massively, although the spin crossover energies are close to identical. As is shown by time-resolved transient spectroscopy and dynamic 1H-NMR line broadening, reference systems deriving from tren (tris-(2-aminoethyl)amine), which greatly lack such trigonal torsion, harbor very rapid spin-state exchange.
Optimizing Melamine Resin Microspheres with Excess Formaldehyde for the SERS Substrate
Authors: Shen Lu , Zhu Junfu , Guo Yuqing , Zhu Zhirong , Wang Xiaogang , Hao Zhixian
Published: September 2017

Influence of the excess monomer within the synthetic reaction solution of melamine resin microspheres (MFMSs) on the surface-enhanced Raman spectroscopy (SERS) enhancement from Rhodamine 6G (R6G) was investigated, where the R6G was adsorbed on the silver nanoparticles (AgNPs) that were loaded on the MFMSs. Surface characteristics of the MFMSs were modified by the excess monomer (i.e., the excessive melamine or formaldehyde) through its terminal overreaction, which can be simply controlled by some of the synthetic reaction conditions, thus further allowing us to optimize the assembly of the loaded AgNPs for the SERS detection. These SERS substrates incorporating the optimized MFMSs with the excess formaldehyde can also be used for tracing analyses of more environmental and food contaminants.
Circumgalactic Oxygen Absorption and Feedback
Authors: Mathews William G. , Prochaska J. Xavier
Published: September 2017

O vi absorption in quasar spectra caused by intervening circumgalactic atmospheres suggests a downturn in the atmospheric column density in sightlines passing beyond about 100 kpc from central star-forming galaxies. This turnover supports the hypothesis that the oxygen originates in the central galaxies. When converted into oxygen space density using an Abel integral inversion, the O vi columns require

M
⊙ of oxygen concentrated near 100 kpc. Circumgalactic gas within this radius cools in less than 1 Gyr and radiates

erg s−1 overall. The feedback power necessary to maintain such oxygen-rich atmospheres for many Gyr cannot be easily supplied by galactic supernovae. However, massive central black holes in star-forming galaxies may generate sufficient accretion power and intermittent shock waves at

to balance circumgalactic radiation losses in late-type

galaxies. The relative absence of O vi absorption observed in early-type, passive

galaxies may arise from enhanced AGN feedback from their more massive central black holes.
A suggested algorithm for detection of multi drug-resistant tuberculosis in Zimbabwe
Authors: Makamure Beauty , Makumbirofa Salome , Bandason Tsitsi , Leccese Paul , Mutetwa Reggie , Robertson Val , Mason Peter
Published: September 2017

Introduction: Rapid genotypic and phenotypic methods for multi-drug-resistant-tuberculosis (MDR-TB) detection are now widely available. Zimbabwe adopted the use of GeneXpert-MTB/RIF, microscopic-observation-drug-susceptibility-assay (MODS) and Mycobacteria-Growth-Indicator-Tube (MGIT) drug-susceptibility-testing (DST). Data is limited on the ideal combination of use of these methods in resource limited settings.

Methodology: Between August 2014 to July 2015, 211 sputa from MDR-TB suspects were tested with GeneXpert-MTB/RIF, MODS, manual-MGIT and Lowenstein-Jensen (LJ)-DST to determine diagnostic accuracy and turnaround-time (TAT), with LJ-DST as the gold standard. A performance score ranking table for diagnostic accuracy, TAT, costs, facilities and expertise requirements, was used to determine the most favourable tool.

Results: GeneXpert-MTB/RIF sensitivity was 96% (95%CI:80-100) and specificity was 95% (95%CI:90-97). MODS sensitivity was 88% (95%CI:68-97) and specificity was 97% (95%CI:87-100). Manual MGIT-DST had slightly lower sensitivity of 80% (95%CI:59-93). Median time to detection of MDR-TB was <1 day (IQR:0-0) for Xpert, 14 days (IQR:11-31) for MODS, 21 days (IQR:7-22) for MGIT-DST and 28 days (IQR:25-28) for LJ-DST. Operational costs for MODS, MGIT-DST, and GeneXpert-MTB/RIF were $21.20, $27.52 and $39.76 respectively. From a summation of scores including facility and expertise requirements per diagnostic technique, GeneXpert-MTB/RIF was the most favourable tool, followed by MODS and MGIT-DST.

Conclusions: For best scale-up of MDR-TB diagnosis in Zimbabwe, GeneXpert-MTB/RIF can be used for rapid detection of TB in smear negative cases, RIF-susceptibility for early treatment initiation and probable MDR-TB. MODS can rapidly confirm probable MDR-TB detected by GeneXpert-MTB/RIF, manual-MGIT can provide early results for susceptibility to other antibiotics, with affordable costs, with LJ-DST confirming discordant DSTs.
KPC: an important mechanism of resistance in K. pneumoniae isolates from intensive care units in the Midwest region of Brazil
Authors: Conci Campos Caroline , Franco Roriz Náthalia , Nogueira Espínola Camila , Aguilar Lopes Fernando , Tieppo Caroline , Freitas Tetila Andyane , Volpe Chaves Claudia Elizabeth , Alexandrino de Oliveira Priscilla , Rodrigues Chang Marilene
Published: September 2017

Introduction: Infections caused by multidrug-resistant Klebsiella pneumoniae are difficult to treat and pose a serious threat to public health worldwide. Here, we describe the presence of carbapenemase-producing K. pneumoniae in intensive care units (ICU) of three major Mato Grosso do Sul hospitals located in the Midwest region of Brazil.

Methodology: A total of 165 K. pneumoniae isolates with reduced susceptibility to carbapenems as identified by the VITEK-2 compact system were studied. Antimicrobial susceptibility testing was performed using the disk diffusion method, as recommended by the Clinical and Laboratory Standards Institute, and the E-test method. The detection of carbapenemase was performed using the modified Hodge test and polymerase chain reaction.

Results: The blaKPC gene was identified in 88.1% (n=89) of the selected K. pneumoniae isolates from Beneficent Association of Campo Grande, 94.9% (n=34) of the isolates from the Regional Hospital of Mato Grosso do Sul and 95.2% (n=26) of the isolates from Maria Aparecida Pedrossian University Hospital. Resistance greater than 80% was observed against cephalosporins, aztreonam, ciprofloxacin and piperacillin/tazobactam. Carbapenemase-producing K. pneumoniae (Kp-KPC) isolates were considered important causative agents of urinary tract infections, pneumonia and bloodstream infections in ICU patients. While rarely reported in the literature, we documented three cases of meningoencephalitis caused by Kp-KPC.

Conclusions: Our study documents the presence of Kp-KPC in three major Mato Grosso do Sul state hospitals, providing key national epidemiology data. This is an important mechanism of resistance in K. pneumoniae isolates from ICU patients and is associated with resistance to multiple classes of antimicrobial drugs.
Molecular characterization of three enteroviral strains isolated in Kuwait from young children with serious conditions
Authors: Chehadeh Wassim , Ali Sanaa Abdulkader Moalim , Maimoona Syeda Mubeen
Published: September 2017

Introduction: Human enteroviruses are single stranded RNA viruses associated with many serious diseases such as encephalitis and myocarditis. They consist of up to 100 immunologically and genetically distinct types. Three enteroviral isolates, 2104, 3936 and 3988, were previously isolated from patients with neurological disorders or sepsis-like illness. In this study, the molecular characterization of the three isolates was investigated.

Methodology: A full genome sequencing was performed by Sanger method, followed by phylogenetic and bootscanning analyses. A detailed analysis of genetic differences between the clinical and prototype isolates were investigated by mapping polymorphisms at nucleotide and amino acid levels, and by comparing RNA secondary structure in the noncoding regions.

Results: Based on the phylogenetic analysis of the VP1 gene and complete genome, 2104 was typed as coxsackievirus B1, 3936 as coxsackievirus B5, and 3988 as echovirus 7. Similarity and bootscan plots provided support for intra- and intertypic recombination crossover points occurring mainly along the nonstructural coding regions of the isolates. A sequence divergence of 12 to 14% was detected in the 5’-noncoding region between the clinical isolates and their corresponding prototype strains. Synonymous and nonsynonymous substitutions could be also mapped to different coding regions of the isolates, including those coding for the Puff, Knob and the hydrophobic pocket of the capsid. Examination of relative frequencies of synonymous and nonsynonymous substitutions in different coding regions of enteroviral isolates showed no evidence for selective pressure.

Conclusion: The results provided a better understanding of the genetic variations, evolution and adaptation of enteroviruses in Kuwait.
Sur les pas de Freud : du démenti pervers au démenti généralisé
Authors: Rey-Flaud Henri
Published: September 2017

La détermination du démenti constitue la dernière avancée capitale de Freud qui bouleverse sa théorie du refoulement et de l’inconscient. Après le chantier initial de l’Homme aux loups (1918) qui met en lumière le clivage du sujet autour de la question de la castration, Freud, en 1927 dans « Le Fétichisme », circonscrit le démenti pervers avant de clôturer sa découverte en 1936 dans sa Lettre à Romain Rolland avec la reconnaissance du démenti généralisé.
Le Ver et le trou : quelques lueurs, pas sans conséquences
Authors: Sidoit Véronique
Published: September 2017

Le fil conducteur de ce travail est la levée du démenti dans son rapport à l’acte, question qui a amené l’auteur à discuter aussi bien de métapsychologie que des conséquences cliniques, éthiques, voire politiques, du démenti et de sa levée. Il s’agit pour l’auteur de questionner ce qui fait point de butée aussi bien dans la clinique que dans le lien social.
Chronique du transport en Belgique
Authors: Daubresse Coraline , Laine Benoît
Published: September 2017

Le Bureau fédéral du Plan et le SPF Mobilité et Transports publient, tous les trois ans, des perspectives de l’évolution de la demande de transport en Belgique. La version de ces perspectives parue en 2015 est présentée ici au travers de ses principaux résultats, en regard de l’évolution observée pour les mêmes indicateurs sur les dernières décennies. Cet exercice permet de donner un contexte global à l’analyse de la thématique du transport en Belgique, et de détailler la manière dont s’articulent les évolutions récentes et le scénario de base de ces perspectives.
Foundations of performance – factors that contribute to excellence in equine exercise
Authors: McKenzie E.
Published: September 2017

Horses are renowned for their incredible capacity for a range of athletic activities, and participation in athletic events arguably represents the most critical strut of the equine industry. Successful performance is typically a primary focus during participation in competitive athletic events, and relies upon a variety of innate physiological and structural factors of the athlete. However, a wide range of external factors also influence performance, and many of these can be readily manipulated. Therefore, thorough assessment of the individual’s inherent capacity for a specific athletic discipline must be combined with optimisation of external factors including nutrition and training to promote excellent performance. Recent progress in methods of athlete selection and monitoring of training responses are assisting continued improvements in equine performance.
Nutraceuticals: a goldmine but for whom?
Authors: McKeever K.H.
Published: September 2017

A whole new industry has grown up around dietary supplements that purportedly can, enhance exercise performance or enhance the recovery from exercise. Many of these new supplements are ‘functional foods’ or nutraceuticals that have active molecules or ingredients that purportedly can reduce inflammation, prevent oxidative stress or have other benefits for whatever may ails an equine athlete. The blitz of advertising that usually accompanies such miracle ergogenic (i.e. performance enhancing) products suggests that a great deal of scientific research has been published to support those claims. Unfortunately, the majority of new dietary supplements are being promoted with little or no scientific basis for the claims made on their labels or in the advertisements touting their benefits. In many cases, no research has been performed to demonstrate efficacy of these new expensive, avant-garde, dietary supplements in the horse. So how can we determine if a new supplement improves recovery from exercise or has potential to improve athletic capacity? The purpose of this review is to outline the important questions a horse owner, trainer, veterinarian, or regulator should ask before deciding it is ok (safety, legality) or even beneficial to feed a supplement to an athletic horse.
Use of Simulation to Integrate Cultural Humility Into Advanced Health Assessment for Nurse Practitioner Students
Authors: Ndiwane Abraham N. , Baker Nancy C. , Makosky Antonia , Reidy Patricia , Guarino Anthony J.
Published: September 2017

Background:

Increasing cultural humility among nursing students requires the application of knowledge and skills. The integration of an Objective Structured Clinical Examination (OSCE) offered nurse practitioner students practice in simulation.

Method:

This learning activity included pre- and postassessments of knowledge regarding cultural issues and level of student satisfaction. Course content included an exemplar video and a simulation interview with an African American standardized patient.

Results:

Of the 65 students enrolled, 97% completed OSCE interviews and 81% completed pre- and postsurveys. A 2-domain 3 × 2-time within-subjects ANOVA indicated a statistically significant interaction effect, reinforced by descriptive statistics. Follow-up pairedttests detected a significantly large knowledge increase. Standardized patient scenarios scored highest for satisfaction, followed by critical thinking, and with self-confidence scoring lowest.

Conclusion:

The favorable knowledge outcomes from this teaching intervention support future applications of OSCE methodology for teaching sensitive cross-cultural content. [J Nurs Educ.2017;56(9):567–571.]
Microcomputer Laboratory Maintenance
Authors: Garrett Norman A. , Lundgren Terry D.
Published: September 2017

The continuing improvement of available technologies has brought unanticipated problems to microcomputer laboratory maintenance. A major problem area in state-of-the-art microcomputer labs is maintenance of the hard disks. Hard disks become corrupted, filled with extraneous files, and are subject to sabotage. The resource costs of maintaining the integrity of the hard disks can be enormous with concomitant loss of user availability. We present a tested, reliable software solution to maintain hard disks which is virtually maintenance free.
Supporting Appropriate User-Developed Applications
Authors: Lally Laura
Published: September 2017

This paper examines User Developed Applications (UDAs) with the goal of providing a framework that managers can use for identifying and supporting appropriate UDAs. Tradeoffs between UDAs and traditionally developed systems throughout the systems development life cycle are identified. Steps that managers can take to: 1) ensure that only appropriate UDAs are developed and 2) improve the logical correctness and usability of the systems in an organizational context are indicated. Finally, suggestions are made for further research aimed at increasing the likelihood of UDA success. Three mini cases are provided as an appendix to illustrate the ideas developed in this analysis.