bluuebunny/crossref_metadata_2025 huggingface dataset:
EU Trade Governance and Policy: A Critical Perspective
Authors: Ford Lucy
Published: April 2022

This article offers a critical analysis of EU trade policy. It does so by highlighting the political and economic enclosures within which EU trade policy is embedded and that continue to hamper more holistic and interdisciplinary analyses that are argued to be necessary in order to comprehend the obstacles to and avenues towards a more sustainable and socially just world. The article critically analyses economic and political hegemony by drawing on two strands of critical international thought, namely neo-Gramscian analysis and global political ecology, employing a critical realist approach. The article identifies the perceived twin short-comings of conventional analyses: firstly, the neglect of understandings of power relations and social justice, and secondly the lack of attention to criteria of sustainability. Within critical debates about European governance, including the governance of trade and trade policy, neo-Gramscian perspectives highlight the power relations within EU governance, exposing the mechanisms of hegemony as well as identifying potential counter-hegemonic forces. While this offers important insights, the article argues that a critical perspective cannot be complete without attention to sustainability. Political ecology makes a vital contribution to critical perspectives by highlighting the natural limits within which by necessity all human activity takes place. Using illustrations from trade policy debates, the article argues that current EU trade policy and governance is not best placed to meet the challenges of sustainability and social justice and it points to the need for more holistic systems thinking to challenge orthodoxy.
EU External Trade and the Treaty of Lisbon: A Revised Neofunctionalist Approach
Authors: Niemann Arne
Published: April 2022

This article analyses the EU’s Common Commercial Policy (CCP) at the level of Treaty revision and particularly focuses on the last Treaty negotiations that led to the Treaty of Lisbon. The analysis is based on a revised neofunctionalist framework that the author developed in previous work. It draws on the following concepts: (i) functional spillover; (ii) cultivated spillover; (iii) social spillover; and (iv) countervailing forces. Insights into the dynamics and countervailing forces driving Treaty revisions considerably deepen our understanding of the Common Commercial Policy, as EU external trade policy-making is substantially affected by the parameters set by the Treaty. The analysis indicates that the revised neofunctionalist framework can broadly account for the changes of the Common Commercial Policy during the last Treaty revision. It is further suggested that integration in the area of trade policy cannot be explained exclusively by rational choice dynamics, such as utility maximizing actors with fixed preferences, but that socialization through deliberation also needs to be taken into account.
COLLABORATIVE GOVERNANCE DALAM PENGEMBANGAN KAWASAN EKONOMI KHUSUS
Authors: Trisniati Elsa , Cadith Juliannes , Sapto Nugroho Kandung
Published: April 2022

The development of tourism is not only conducted by one stakeholder, but it involves various stakeholders and therefore needs the collaboration among them. The purpose of this research is to describe the collaborative governance in developing the special economic zone of Tanjung Lesung. The description of collaborative governance is based on collaborative governance model that emphasizes four dimensions, namely starting condition, institutional design, facilitative leadership, and collaboration process. Method of this research is descriptive-qualitative method. This research needs primary and secondary data. Primary data of this research are collected by in-depth interview and observation, and secondary data of this research are collected by documentation. The collected data, both primary and secondary, are qualitatively described. Results of this research indicate that the collaborative governance based on the dimensions of starting condition, institutional design, facilitative leadership, and collaboration process in developing the special economic zone of Tanjung Lesung is not optimally implemented yet. This research recommends that the community increases its resources in order to involve in collaboration; the government provides the sustained training to help the community in order to actively collaborate and forms a special forum to communicate and discuss the vision and mission to be commonly achieved in developing the special economic zone of Tanjung Lesung.
Principais necessidades humanas básicas afetadas em pacientes com câncer e tromboembolismo venoso: revisão integrativa
Authors: Vidigal Paula Dias , Fuly Patrícia dos Santos Claro , Fuly Patrícia dos Santos Claro , Santos Mauro Leonardo Salvador Caldeira dos , Camacho Alessandra Conceição Leite Funchal , Souto Marise Dutra , Santos6 Sonia Carvalho
Published: April 2022

Objetiva-se identificar as principais necessidades humanas básicas afetadas em pacientes com câncer e tromboembolismovenoso baseando-se nas evidências de problemas de enfermagem identificadas na literatura científica, segundo oreferencial conceitual de Wanda Horta. Revisão integrativa de literatura para identificação de problemas de enfermagempara pacientes com câncer e tromboembolismo venoso. A análise dos dados foi feita através da seleção e agrupamentode evidências empíricas conforme a Necessidade Humana Básica afetada. 151 evidências empíricas foram identificadas,relacionadas à 18 diferentes Necessidades Humanas Básicas, sendo 11 necessidades psicobiológicas e 07 psicossociais.Conclui-se que os problemas de enfermagem identificados distribuem-se em necessidades psicobiológicas epsicossociais. Dentre as necessidades mais afetadas destacam-se: regulação vascular, percepção dolorosa, oxigenaçãoe integridade cutâneo-mucosa/integridade física. Sugere-se a produção de outros trabalhos que tratem do processo deenfermagem, com consequente elaboração de diagnósticos e de intervenções de enfermagem para pacientes com câncere tromboembolismo venoso, com posterior validação dos mesmos.Palavras-chave: Enfermagem Oncológica; Tromboembolia Venosa; Processos de Enfermagem.
Detection of Biomarkers for Epithelial-Mesenchymal Transition with Single-Cell Trajectory Inference
Authors: Murayama Kosho , Matsuda Hideo
Published: April 2022

Background: Epithelial-mesenchymal transition (EMT) has been recognized as playing a crucial role in cancer progression. Among the studies on EMT, biomarker detection has been one of the important topics to understand the biology and mechanism of EMT related to tumor progression and treatment resistance. The existing methods often identified differentially-expressed genes as potential markers by ranking all genes by their variances. This paper proposes a novel method to detect markers for respective lineages in the EMT process. Methods and Results: Our method consists of three steps: first, perform trajectory inference to identify the lineage of transitional processes in EMT progression, and secondly, identify the lineage for EMT reversion in addition to EMT progression, and thirdly detect biomarkers for both of the EMT progression and reversion lineages with differential expression analysis. Furthermore, to elucidate the heterogeneity of the EMT process, we performed a clustering analysis of the cells in the EMT progression and reversion conditions. We then explored branching trajectories that order clusters using time information of the time-course samples. Using this method, we successfully detected two potential biomarkers related to EMT, phospholipid phosphatase 4 (PLPP4) and lymphotoxin-beta (LTB), which have not been detected by the existing method. Conclusions: In this study, we propose a method for the detection of biomarkers of EMT based on trajectory inference with single-cell RNA-seq data. The performance of the method is demonstrated by the detection of potential biomarkers related to EMT.
Safety and Efficacy of Systemic Anti-Scg3 Therapy to Treat Oxygen-Induced Retinopathy
Authors: Dai Chang , Tian Hong , Bhatt Amit , Su Guanfang , Webster Keith A. , Li Wei
Published: April 2022

Background: To circumvent possible systemic side effects, anti-angiogenic drugs targeting vascular endothelial growth factor (VEGF) for ocular neovascular diseases in adults are approved only for intravitreal administration. However, intravitreal injection itself can elicit injection-related adverse effects, and premature eyes of infants with retinopathy of prematurity (ROP) may be particularly susceptible to intravitreal injection. Therefore, an unmet clinical need is to develop safe systemic anti-angiogenic therapies for ROP. We recently reported that secretogranin III (Scg3) is a disease-restricted angiogenic factor and that systemic anti-Scg3 mAb alleviates ROP in animal models with minimal side effects on developing eyes and organs. The aim of this study is to investigate the safety and efficacy of a humanized anti-Scg3 antibody via systemic administration. Methods: We analyzed the safety and efficacy of a humanized anti-Scg3 antibody Fab fragment (hFab) delivered by intraperitoneal injection in oxygen-induced retinopathy (OIR) mice, a surrogate model of ROP. Results: The results showed that systemic anti-Scg3 hFab effectively alleviated pathological retinal neovascularization in OIR mice with similar efficacy to the anti-VEGF drug aflibercept. Systemic aflibercept conferred significant adverse side effects in neonatal mice, including reduced body weight, abnormalities in retinal and renal development, and retarded physiological neovascularization, whereas systemic anti-Scg3 hFab elicited no such side effects. Conclusions: The findings suggest that systemic anti-Scg3 hFab is a safe and effective therapy for OIR and support further development for ROP treatment.
Age Distribution of 4526 Surgically Excised Specimens of Eye Tumors by Histopathological Examination in China
Authors: Li Xiaohua , Ying Guishuang , Liu Xiaohui , Yuan Min , Yin Ruijie
Published: April 2022

Background: Cumulative evidence suggests that the risk of eye tumors varies among different age groups and populations. The purpose of the present study was to assess the age distribution of eye tumors in China. Methods: In this retrospective study, the age distribution of various types of eye tumors was analyzed on surgically excised and histologically confirmed specimens obtained from 4492 patients (4526 eyes), collected between 2001 and 2017. Results: Of the 4526 specimens, 3156 eyes (69.7%) had benign eye tumors, while 1370 eyes (30.3%) had malignant tumors. The age-specific incidence of eye tumors was characterized by a bimodal distribution, one peak occurred at age 0–9 years (19.7%) and the other at 50–59 years (14.7%) of age. Malignant eyelid tumors were very rare under the age of 20 years, but increased to 78% of all eyelid tumors by the age of 70 years. Children aged 0–9 years old were 6.5 times as likely to have a malignant eye tumor (95% CI, 4.1–10.4) as those aged 10–19 years. The age-related variation of eye tumors was also observed in the top ten categories of both benign (p < 0.001) and malignant types (p = 0.001). Conclusions: These results showed that age is a major factor determining the type of eye tumor, confirmed by histopathological analysis.
Targeted Therapy in the Management of Modern Craniopharyngiomas
Authors: Reyes Maikerly , Taghvaei Mohammad , Yu Siyuan , Sathe Anish , Collopy Sarah , Prashant Giyarpuram N. , Evans James J. , Karsy Michael
Published: April 2022

Background: The proximity of craniopharyngiomas (CPs) to critical neurovascular structures can lead to a host of neurologic and endocrine complications that lead to difficulty with surgical management. In this review, we examine the molecular and genetic markers implicated in CP, their involvement in tumorigenic pathways, and their impact on CP prognosis and treatment. Methods: We undertook a focused review of relevant articles, clinical trials, and molecular summaries regarding CP. Results: Genetic and immunological markers show variable expression in different types of CP. BRAF is implicated in tumorigenesis in papillary CP (pCP), whereas CTNNB1 and EGFR are often overexpressed in adamantinomatous CP (aCP) and VEGF is overexpressed in aCP and recurrent CP. Targeted treatment modalities inhibiting these pathways can shrink or halt progression of CP. In addition, EGFR inhibitors may sensitize tumors to radiation therapy. These drugs show promise in medical management and neoadjuvant therapy for CP. Immunotherapy, including anti-interleukin-6 (IL-6) drugs and interferon treatment, are also effective in managing tumor growth. Ongoing clinical trials in CP are limited but are testing BRAF/MET inhibitors and IL-6 monoclonal antibodies. Conclusions: Genetic and immunological markers show variable expression in different subtypes of CP. Several current molecular treatments have shown some success in the management of this disease. Additional clinical trials and targeted therapies will be important to improve CP patient outcomes.
Taxonomic position, antibiotic resistance and virulence factors of clinical Achromobacter isolates
Authors: Fluit Ad C. , Bayjanov Jumamurat R. , Aguilar María Díez , Benaissa-Trouw Barry , Tunney Michael M. , Westreenen Mireille van , Meis Jacques F. , Elborn J Stuart , Cantón Rafael , Ekkelenkamp Miquel B.
Published: April 2022

The role of Achromobacter species in lung disease remains unclear. The aim of this study was to characterize Achromobacter isolated from persons with cystic fibrosis and from other clinical samples. Whole genome sequences from 101 Achromobacter isolates were determined (81 from patients with cystic fibrosis and 20 from other patients) and analysed. Taxonomic analysis showed nine species including two putative novel species. Thirty-five novel sequence types were present. The most active agent was co-trimoxazole followed by imipenem, but Minimal Inhibitory Concentrations (MICs) were high. Acquired antibiotic resistance genes were rare. Their presence did not correlate with minimal inhibitory concentrations suggesting that other mechanisms are involved. Genes for proposed virulence factors were present in only some isolates. Two putative novel species were identified. The putative virulence properties of Achromobacter involved in infections are variable. Despite the high MICs, acquired resistance genes are uncommon.
The Interaction of Severe Obstructive Sleep Apnea Hypopnea Syndrome and Abdominal Obesity on Cognitive Function
Authors: Fan Xin , Zhong Yun , Li Jia-qi , Zhang Ling-ling , Xiong Yuan-ping , Zhang Zhi-yuan , Xia Yun-yan
Published: April 2022

Background: Both obstructive sleep apnea-hypopnea syndrome (OSAHS) and obesity are related to cognitive deficits, but the interaction effects of OSAHS and abdominal obesity on cognitive function are unclear. Thus, we performed this study to investigate this issue. Methods: We recruited subjects who received polysomnography test, anthropometric measurements and cognitive function assessment and/or blood protein test. Correlations between apnea-hypopnea index (AHI) and cognitive function were assessed. Analysis of covariance was used to compare the differences in cognitive function between groups and detect the interactions of OSAHS and obesity on cognitive function. Multiple linear regression models were used to determine the associations between OSAHS and cognitive function. Results: In total, 196 subjects with Montreal Cognitive Assessment (MoCA), 161 subjects with Symbol Digit Modalities Test (SDMT) and Trail making test, and 44 subjects with blood protein test were enrolled. Significant negative correlations between AHI and visuo-spatial and executive, language, delayed recall and total score of MoCA were observed. After adjusting for multiple confounding factors, subjects with severe OSAHS had significant lower delayed recall score and total score of MoCA, SDMT index, and Aβ40 protein level than those with non-severe OSAHS group. Severe OSAHS was independently negatively associated with delayed recall score and total score of MoCA, SDMT index, and Aβ40 protein level. An interactive effect of severe OSAHS and abdominal obesity on language score of MoCA was found. Conclusions: Severe OSAHS increased the risk of cognitive deficits. Interaction effect of severe OSAHS and abdominal obesity on language was seen.
Peter Martynovich Meyer — the first chief of staff of the Caucasian Linear Cossack Army
Authors: Nikolaenko Nikolay , Kolesnikov Ilya , Klimova Natalya , Goroshko Olga
Published: April 2022

The article, based on the analysis of published sources, provides information directly related to the career of officer P.M. Meyer (until 1854). The purpose for which the post of chief of staff of the Caucasian Linear Cossack Army was established and for what period of time P.M. Meyer occupied it is investigated. The authors consider in detail his official duties and special assignments, which were entrusted to him by the high command, some facts of his biography are considered.
Volost administration and local self-government in a modern Chinese village: from people’s communes to volosts and committees of fellow villagers (the 80s of the 20th century — the beginning of the 21st century)
Authors: Mayorov Vladimir , Stezhenskaya Lydia
Published: April 2022

This article continues a historical outline of the rural municipality administration and local self-government in rural China and Taiwan. The authors analyze volost administration and local self-government in a modern Chinese village.
Aspek permodalan koperasi
Authors: rusdin Zahra amaliyah
Published: April 2022

Undang-undang nomor 17 tahun 2012 tentang perkoperasian mempertegas kedudukan koperasi sebagai badan hukum yg ditandai dengan adanya pemisahan kakayaan para anggotanya sebagai modal awal untuk menyelenggarakan usaha koperasi .
ASPEK PERMODALAN KOPERASI
Authors: Agnusia Nur Adillah
Published: April 2022

Aspek permodalan yang dimaksud merupakan pengukuran bagaimana serta berapa modal bank tersebut dapat memadai dalam menunjang setiap kebutuhannya. Modal Kerja menurut Jumingan (2011:6) yaitu jumlah dari aset lancar. Defnisi ini bersifat kuantitatif karena menunjukkan jumlah dana yang digunakan untuk maksud operasi-operasi jangka pendek. Waktu tersedianya modal akan tergantung pada macam dan tingkat likuiditas dari unsur-unsur aset lancar misalnya kas, suratsurat berharga, piutang dan persediaan. Sedangkan Modal Kerja menurut Kasmir (2012:205) merupakan modal yang digunakan untuk melakukan kegiatan operasi perusahaan. Modal diartikan sebagai investasi yang ditanamkan dalam aset lancar atau aset jangka pendek seperti kas, surat-surat berharga, piutang, persediaan dan aset lancar.
NeuroLibre : A preprint server for full-fledged reproducible neuroscience
Authors: Karakuzu Agah , DuPre Elizabeth , Tetrel Loic , Bermudez Patrick , Boudreau Mathieu , Chin Mary , Poline Jean-Baptiste , Das Samir , Bellec Pierre , Stikov Nikola
Published: April 2022

NeuroLibre is a preprint server for neuroscience Jupyter Books, blending code, visualization and narrative text into one document. NeuroLibre archives the environment, code and data and also implements a technical review to ensure readers can reproduce the work. NeuroLibre offers an online platform where readers can reproduce or modify each preprint from a web browser, without any installation required. We hope that NeuroLibre will contribute to usher the research community in a new area of open and reproducible neuroscience. The preprint server is built with open source components, and can be freely adapted to meet the needs of other communities in the future as well.
The Between-Person and Within-Person Effects of Intergroup Contact on Outgroup Attitudes: A Multi-Context Examination
Authors: Friehs Maria-Therese , Bracegirdle Chloe , Reimer Nils Karl , Wölfer Ralf , Schmidt Peter , Wagner Ulrich , Hewstone Miles
Published: April 2022

The contact hypothesis proposes that intergroup contact improves outgroup attitudes. Existing cross-sectional and longitudinal studies provide valuable insights into the association between contact and attitudes, but are mostly uninformative regarding within-person and between-person effects. To investigate such effects, we applied (random-intercept) cross-lagged panel model analyses in two studies featuring diverse study characteristics. We found longitudinal associations between contact and attitudes in conventional cross-lagged panel models. These associations were, however, ascribed purely to between-person effects, not within-person effects, in random-intercept cross-lagged panel models. The lack of within-person effects conflicts with the contact hypothesis, which assumes that contact affects individuals’ attitudes. To investigate the possibility that between-person effects represent spurious correlations caused by confounders, we examined the extent to which demographic characteristics, intergroup ideologies and personality traits explain between-person effects. Our findings highlight the need to further investigate within-person effects and the factors that may explain between-person differences in contact and attitudes.
ASPEK-ASPEK PERMODALAN KOPERASI
Authors: Agnusia Nur Adillah
Published: April 2022

Koperasi adalah suatu badan usaha yang secara sukarela dimiliki dan dikendalikan oleh anggota yang adalah juga pelanggannya dan dioperasikan oleh mereka dan untuk mereka atas dasar nirlaba atau dasar biaya. Modal Kerja merupakan modal atau investasi yang digunakan nantinya untukmelakukan kegiatan operasi suatu perusahaan yang ditanamkan dalam aset-aset perusahaan. Dalam koperasi modal terbagi menjadi 2 yaitu modal jangka panjang dan modal jangka pendek. Modal koperasi itu terdiri dari dan dipupuk dari simpanan-simpanan, yaitu simpanan wajib, simpanan pokok dan simpanan sukarela. Kemudian pinjaman-pinjaman, penyisihan-penyisihan dari hasil usahanya termasuk cadangan serta sumber-sumber lain.
Ilmu Komunikasi Dalam Al-Quran
Authors: Bobihu Amina
Published: April 2022

Tujuan dari penelitian ini adalah untuk mengetahui konsep komunikasi dalam kesucianAlquran. Penelitian ini merupakan penelitian kualitatif yang menerapkan teologi sosialmendekati. Hasil penelitian ini mengungkapkan bahwa Al-Qur'an menggambarkan konsep tersebutkomunikasi menjadi beberapa bentuk. Oleh karena itu, para cendekiawan muslim mengklaim bahwa adaAda delapan bentuk komunikasi yang disebutkan dalam Al-Qur'an, yaitu qaulkarim, qaul ma'ruf, qaul layyin, qaul adzim, qaul balig, qaul maisur, qaul tsaqil,dan qaul sadid. Lebih jauh, Al-Qur'an menginformasikan bahwa dalam komunikasi, seseorang perlu untukmenganggap komunikan untuk mencapai suatu tujuan yang disengaja. penentuan dariBentuk komunikasi yang dipilih untuk digunakan telah ditawarkan dalam Al-Qur'an sebagai cara alternatif dalamTujuan dari penelitian ini adalah untuk mengetahui konsep komunikasi dalam kesucianAlquran. Penelitian ini merupakan penelitian kualitatif yang menerapkan teologi sosial.
HYDROGEN-INDUCED CALCITE DISSOLUTION IN AMALTHEENTON FORMATION CLAYSTONES: IMPLICATIONS FOR UNDERGROUND HYDROGEN STORAGE CAPROCK INTEGRITY
Authors: Bensing Joel , Misch David , Skerbisch Lukas , Sachsenhofer Reinhard
Published: April 2022

With the rising potential of underground hydrogen storage (UHS) in depleted oil and gas reservoirs or deep saline aquifers, questions remain regarding changes to geological units due to interaction with injected hydrogen. Of particular importance is the integrity of potential caprocks/seals with respect to UHS. The results of this study show significant dissolution of calcite fossil fragments in claystone caprock proxies that were treated with a combination of hydrogen and 10 wt% NaCl brine. This is the first time it has been experimentally observed in claystones. The purpose of this short communication is to document the initial results that indicate the potential alteration of caprocks with injected hydrogen, and to further highlight the need for hydrogen-specific studies of caprocks in areas proposed for UHS.
Range Geolocation Accuracy of C-/L-Band SAR and Its Implications for Operational Stack Coregistration
Authors: Yunjun Zhang , Fattahi Heresh , Pi Xiaoqing , Rosen Paul , Simons Mark , Agram Piyush , Aoki Yosuke
Published: April 2022

Time series analysis of synthetic aperture radar (SAR) and interferometric SAR generally starts with coregistration for the precise alignment of the stack of images. Here we introduce a model-adjusted geometrical image coregistration (MAGIC) algorithm for stack coregistration. This algorithm corrects for atmospheric propagation delays and known surface motions using existing models and ensures simplicity and computational efficiency in the data processing systems. We validate this approach by evaluating the impact of different geolocation errors on stacks of C-band Sentinel-1 and L-band ALOS-2 data, with a focus on the ionosphere. Our results show that the impact of the ionosphere dominates Sentinel-1 ascending (dusk-side) orbit and ALOS-2 data. After correcting for ionosphere using the JPL high resolution global ionospheric maps, with topside total electron content (TEC) estimated from GPS receivers onboard the Sentinel-1 platforms, solid Earth tides, and troposphere, the mis-registration RMSE reduces by over a factor of four from 0.20 m to 0.05 m for Sentinel-1 and from 2.66 m to 0.56 m for ALOS-2. The results demonstrate that for Sentinel-1, the MAGIC approach is accurate enough in the range direction for most applications including interferometry; while for the L-band SAR, it can be potentially accurate enough if topside TEC is available. Based on our current understanding of different error sources, we evaluate the expected range geolocation error budget for the upcoming NISAR mission with an upper bound of the relative geolocation error of 1.3 m and 0.2 m for its L- and S-band SAR, respectively.
KEMASAN PINTAR BERBASIS EKSTRAK UBI UNGU SEBAGAI INDIKATOR KESEGARAN FILET IKAN PATIN PADA SUHU CHILLER
Authors: Ningtyas Rina , Saraswati Anisa Dewi
Published: April 2022

Ikan patin (pangasius sp.) mengandung lemak dan protein tinggi sehingga rentan mengalami pembusukan. Untuk mengurangi risiko tersebut, dilakukan pendinginan pada penyimpanan serta pengemasan ikan patin dengan penambahan indikator kesegaran untuk mempermudah konsumen mengenali kualitas ikan. Penelitian ini bertujuan untuk mengetahui perubahan warna indikator selama masa penyimpanan, serta mengetahui korelasi perubahan warna label indikator dengan mutu ikan patin. Label indikator dibuat menggunakan pewarna alami berupa antosianin dari ekstrak ubi ungu. Ubi ungu diekstraksi dengan menggunakan alkohol 70%, kemudian dilakukan variasi pH pada lautan ekstrak (pH 2, 5, 8, dan 11). Variasi pH ini digunakan sebagai larutan indikator. Sensitivitas larutan terhadap gas amin diuji dengan menggunakan NH4OH yang diletakan bersama larutan indikator di wadah tertutup selama 2 jam. Pengujian label indikator dilakukan dengan aplikasi pada ikan patin, selain itu dilakukan pengukuran nilai L*a*b*, pH ikan, dan uji organoleptik yang dilakukan setiap 4 hari selama 12 hari dengan 2 ulangan. Hasil uji sensitivitas didapatkan bahwa larutan indikator sensitif dan menujukkan perubahan warna terhadap uap NH3 yang dihasilkan selama pengujian. Berdasarkan pengukuran nilai L*a*b, variasi pH 2 dan 5 menghasilkan perubahan warna yang signifikan dan sesuai dengan hasil pengamatan secara visual dimana warna label berubah dari merah muda dan ungu menjadi biru muda. Sedangkan variasi pH 8 dan 11 tampak terjadi pemudaran warna. Hasil pengukuran pH awal 7.4±0.0 dan pH akhir 7.7±0.28. Hasil uji organoleptik menunjukan ikan sudah tidak segar pada hari ke-4 berdasarkan penilaian kenampakan, bau, dan tekstur (SNI 2729:2013). Kesimpulan yang didapatkan adalah ekstrak antosianin ubi ungu dapat digunakan untuk mendeteksi kesegaran ikan patin.
Dialogue in In-Depth Cognition of the Subject’s Psyche: Functioning of Pragmatic Referent Statements
Authors: Yatsenko Tamara , Ivashkevych Ernest , Halushko Lyubov , Kulakova Larysa
Published: April 2022

The aim of our research was also to analyze the dialogue in in-depth cognition of the subject’s psyche in the psycholinguistic paradigm. The latter allows us to distinguish pragmatic-explicit and pragmatic-implicit reference statements in psychoanalytic dialogues, to classify such statements, to give their characteristics, which will further help psychoanalysts to build dialogues with patients in psychotherapeutic practice.

Methods. In our research we’ve used author’s Psychodynamic Methodology of organizing of psychotherapeutic process, which contributes to the problem of understanding the essence of the patient’s psyche. The improvement of diagnostic tools stipulated the clarification of the focus of the process of active socio-psychological cognition on optimizing the psyche of the patient in the psychotherapeutic process. Also we proposed group method of active socio-psychological cognition (hereinafter referred to as the ASPC) which emphasized on a law of positive disintegration of the psyche of the person and its secondary integration at a higher level of mental development of a man (Yatsenko, 2020).

Results. The nature of emphasized by us pragmatic-implicit reference statements, the peculiarities of their functioning in the whole text fragment will resemble semantic performatives. In the paradigm of pragmatic statements, we will accept them as pragmatic statements. Although both pragmatic-implicit and pragmatic-explicit reference statements are very important for psychoanalytic dialogues. Pragmatic-explicit reference statements have all the features of performatives and can be fully characterized as pragmatic performatives.

Conclusions. It was proved that positive pragmatic-explicit and pragmatic-implicit reference statements in psychoanalytic dialogue allowed us to identify the links between superficial and hidden semantic parameters of the patient’s psyche, which under the conditions of comprehension of his/her consciousness can open up prospects for their individual reconstruction by the subject, without the psychoanalyst’s help. This process facilitates the harmonization and functional optimization of the psyche of the person in in-depth correctional process. This way of solving a problem by a person sets the awakening of adequate capabilities of the subject, making by the patients’ some adjustments to their own behavior by expanding and deepening the boundaries of self-awareness in the process of active socio-psychological cognition.
Дослідження ґенези розуміння текстів інтернету в юнацькому віці залежно від рівня мисленнєво-мовленнєвого розвитку
Authors: Akimova Nataliia , Akimova Alina , Akimova Anastasiya
Published: April 2022

Мета. Представити результати вивчення специфіки розуміння текстів інтернету читачами юнацького віку; дослідити особливості ґенези розуміння текстів інтернету залежно від рівня мисленнєво-мовленнєвого розвитку, притаманного певному читачеві; виявити закономірності динаміки успішності розуміння зі зростанням рівня мисленнєво-мовленнєвого розвитку на кожному етапі процесу розуміння.

Методи і методики. У дослідженні використані теоретичні (дедукція, індукція, аналіз, синтез, узагальнення, систематизація), емпіричні (експеримент, метод семантичних і прагматичних інтерпретацій, контент-аналіз; суб’єктивного шкалування) та статистичні методи (первинна статистика, кореляційний аналіз). Вибірка склала 122 особи чоловічої та жіночої статі. Вивчення специфіки розуміння проводилося за авторською методикою “Успішність розуміння текстів інтернету”, що представлена у статті. Рівень мисленнєво-мовленнєвого розвитку респондентів було визначено за допомогою низки стандартизованих тестів, зокрема тесту Еббінгауза, методики “Встановлення закономірностей” Б.Л. Покровського, КОТ (короткий орієнтовний відбірковий тест В.Н. Бузина, Е.Ф. Вандерліка, опитувальник діагностики інтелекту).

Результати. У дослідженні було встановлено, що чим вищий рівень розвитку когнітивної сфери досліджуваних, тим активніше вони читають тексти інтернету та точніше можуть прогнозувати зміст тексту за малюнком, проте дещо гірше за назвою. Успішність інтерпретації також покращується зі зростанням рівня мисленнєво-мовленнєвого розвитку, незалежно від типу тексту інтернету. На етапі емоційної ідентифікації ґенеза розуміння текстів інтернету визначається рівнем мисленнєво-мовленнєвого розвитку лише щодо узгодженості емоційної оцінки, яка залежить від специфіки тексту інтернету.

Висновки. Доведено, що рівень мисленнєво-мовленнєвого розвитку юнаків впливає на успішність їх розуміння текстів інтернету. Особливо відчутній цей вплив на етапах рецепції та інтерпретації. На етапі емоційної ідентифікації рівень мисленнєво-мовленнєвого розвитку впливає лише на узгодженість емоційної оцінки і лише щодо окремих типів текстів інтернету.
Penanaman Nilai Nasionalisme Melalui Kepedulian Lingkungan Alam dalam Novel Si Anak Pemberani Karya Tere Liye
Authors: Permatasari Nur Endah
Published: April 2022

Tujuan dari penelitian ini, yaitu untuk mendeskripsikan (1) wujud nilai nasionalisme dalam novel Si Anak Pemberani karya Tere Liye, (2) relevansi novel Si Anak Pemberani karya Tere Liye dengan pembelajaran Bahasa Indonesia di SMA/MA. Jenis penelitian ini termasuk dalam penelitian kepustakaan (library research). Penelitian ini menggunakan metode deskripsi kualitatif dengan pendekatan sosiologi sastra. Data dan sumber data penelitian ini berupa novel Si Anak Pemberani karya Tere Liye dan sumber buku referensi maupun artikel-artikel yang mendukung dan menunjang permasalahan penelitian. Teknik penelitian menggunakan teknik pustaka, teknik simak, dan teknik catat. Teknik pemeriksaan keabsahan data menggunakan teknik triangulasi teori. Teknik analisis data yang digunakan menggunakan teknik analisis data interaktif, yaitu mengumpulkan data, reduksi data, penyajian data, dan menarik kesimpulan/verifikasi. Hasil dari penelitian ini dapat disimpulkan bahwa novel Si Anak Pemberani karya Tere Liye mengandung: (1) tiga prinsip nasionalisme, meliputi: a) kesatuan wilayah tanah air, bangsa, bahasa, ideologi, aturan negara, sistem politik, sistem ekonomi, sisten keamanan, dan kebijakan kebudayaan, b) mempunyai harga diri, perasaan bangga dan sayang terhadap identitas bangsa, dan c) berprestasi: cita-cita untuk menciptakan kesejahteraan, kebesaran, dan kemuliaan bangsa, (2) novel ini relevan dengan pembelajaran Bahasa Indonesia di SMA/MA pada KI 2 (sikap). Kata kunci: Nasionalisme, Lingkungan Alam, Novel
Crises fébriles : mise au point pour le médecin aux urgences
Authors: Guedj R. , De Suremain N. , Cavau A. , Enault M. , Carbajal R.
Published: April 2022

Les crises fébriles (CF), définies comme des crises d’épilepsie en contexte fébrile chez un enfant âgé entre six mois et cinq ans sans infection du système nerveux central affectent entre 2 et 5 % des enfants. Leur pronostic à long terme est excellent, n’exposant ni à un excès de mortalité ni à une diminution des compétences intellectuelles et comportementales. Poser le diagnostic de CF nécessite d’éliminer les autres causes de crises d’épilepsie en contexte fébrile, dont une méningite bactérienne et une méningoencéphalite herpétique. Cependant, le diagnostic de CF ne nécessite généralement aucun examen complémentaire sous réserve d’un interrogatoire et d’un examen clinique minutieux. L’indication des examens complémentaires pour identifier l’étiologie de la fièvre n’est pas modifiée par le fait que l’enfant ait présenté une CF. Bien qu’un tiers des enfants ayant eu une CF récidiveront au moins une fois avant l’âge de cinq ans, aucune mesure prophylactique (traitement antiépileptique, prise en charge agressive de la fièvre) n’est indiquée pour éviter ces récidives pour la quasi-totalité de ces enfants. Plusieurs facteurs de risque d’épilepsie sont à rechercher pour identifier les rares patients nécessitant un avis spécialisé sans urgence. Enfin, assister à un épisode de CF est une expérience très éprouvante pour les parents. Plusieurs messages clés doivent être délivrés aux parents avant le retour au domicile dans le but d’améliorer leur compréhension de l’épisode qui a eu lieu et de prévenir un syndrome posttraumatique ainsi que des modifications du comportement parental face à la fièvre.
Evaluation of the adaptability of introduced strawberry varieties in the conditions of the Samara Region
Authors: Antipenko M. I. , Zaika A. S.
Published: April 2022

The article presents the results of assessing the adaptability of introduced strawberry varieties of foreign breeding, according to economically valuable traits for their further use in breeding and cultivation in the conditions of the Samara region. In the State Register for the Middle Volga region, the assortment of strawberries is represented by 13 varieties. Almost all varieties are outdated, do not meet modern requirements and do not have the necessary complex of economically valuable traits. Strawberry varieties must be regularly updated in accordance with the increasing requirements of producers and consumers of marketable products. Strawberry varieties from other climatic regions adapt with great difficulty to new conditions, do not realize their biological potential and do not correspond to the characteristics declared by the originating institutions. At the same time, strawberries do not have varieties that are able to realize their potential in different environmental conditions. The aim of the study was to study 12 newest introduced strawberry varieties of foreign breeding by frigo seedlings, compared them with each other, highlighting varieties with maximum performance. Collection variety study was carried out according to a reduced program in the amount of 25 plants of each variety without repetition. The research was carried out in Research Institute of Horticulture and Medicinal Plants « Zhigulevskie Sady» on the site of the breeding department in 2019-2021. As a result of the collection variety study of 12 strawberry varieties in the conditions of the Samara region, a significant influence of weather conditions on the passage of phenological phases was revealed. According to the timing of flowering and ripening of berries, strawberry varieties were divided into groups: early, middle, late, remontant. The early group included 3 varieties: Asia, Liya sakharnaya, Clery. There are 4 varieties in the medium group: Camarosa, Syria, Molling Santineri, Olympia. In the group of late there are 2 varieties: Eliani, Sensatsiya. There are 3 remontant varieties: Garmoniya, Murano, Charlotte. By large-fruitedness of more than 12 g, the following varieties stood out: Olympia, Asia, Liya sakharnaya, Molling Santineri, Sensatsiya. The other varieties in the group are large (9-12 g), except for the Camarosa variety. The sources of largefruitedness, dessert taste, high transportability of berries and early ripeness of the variety were identified: Asia, Liya sakharnaya. Varieties with high plasticity and productivity for growing conditions have been revealed: Asia, Sugar Leah, Sensatsia, Molling Santinary, Garmoniya.
The incredible boong gi: Educational game RPG for mathematical understanding ability
Authors: Setiyani Setiyani , Sumarwati Sri , Sagita Laela , Fadhlurrohman Dzaki
Published: April 2022

Some of the android-based mobile game genres that are currently very popular such as adventure, first-person shooter, fighting, racing, and others. This development should provide opportunities in the field of education to make games not only for fun but also for education. The purpose of this study was to produce educational games that were valid, practical, and had potential effects to improve the mathematical understanding of the relationship and function of junior high school students. The research method used is RD (research development) using the ADDIE model. The data collection techniques used were documentation, interviews, and tests of mathematical comprehension abilities. The results obtained from the game "The Incredible Boong Gi" are valid with an average of 96.70% of expert validators and media validators. The results of the practicality questionnaire from 9 students averaged 90.32%. The results of data analysis show that educational RPG games have valid, practical criteria and have potential effects. RPG games are valid in terms of relevance, systematics, student-centered compatibility, game design, and compatibility. RPG games get practical results from implementation in small groups. Furthermore, the educational RPG prototype has the potential effect of improving students' mathematical understanding abilities. RPG games provide a fun learning atmosphere, by playing students can also learn. Making RPG games is also not difficult, according to the competence of students to be achieved and challenges the creativity of the teacher.
The positive politeness strategies used on whatsapp conversation between student and teacher in English learning at al-luthfah Islamic school
Authors: Santoso Dwi , Indriani Novita
Published: April 2022

This Study discusses WhatsApp conversations between students and teachers used while learning English used in teaching activities to determine the type of politeness used by students in WhatsApp conversations during English learning at the al-Lutfah Islamic school. This research uses descriptive qualitative as the research method. The research subject is Student and teacher, while the study's object is politeness strategies in conversation WhatsApp that may contain politeness. The data of this research is the WhatsApp conversation of having politeness strategies. It uses observation and takes notes to collect the data. The data analyzing method is metode agih. The participants of this research are teachers and students at Al-Luthfah Islamic school. The transcriptions were analyzed and discussed based on the politeness of Brown and Levinson (1987). This study's findings reveal the kinds of politeness types used by Al-Luthfah Islamic students to encode politeness or politeness. In the form of several messages when replying to several statements in the WhatsApp group. These expressions are in the form of greetings, gratitude, ask questions, express opinions, and several forms of these messages are stages of obtaining data, identifying data, looking for standards, classifying types of politeness, and finding their function of the politeness used. And analyze the data.
Is a triangle 180 degrees? Using relevant material to explore elementary school students’ reasoning ability
Authors: Chen Jihe , Zhou Ying , Tanu Wijaya Tommy , Tamur Maximus
Published: April 2022

Students’ proof construction is one of the important abilities in learning mathematical knowledge. To understand the development of Students’ proof construction of the fourth-grade students in Guilin, 15 fourth-grade students were selected to conduct an exploration activity about the sum of the inner angles of a triangle is equal to 180°. Through the observation and interview with students in the activities, we conclude that the reasonable ability of excellent students has coherence and integrity, the middle level students’ proof construction is ordinary and still need to improve, and the Low Students’ proof construction students are weak, and it is difficult to understand the research object. The teacher must have a creative and interesting method to teach students to improve Students’ proof construction from the research process and results.
Nearpod as a tool for increasing students’ motivation for learning chemistry
Authors: Naumoska Aleksandra , Rusevska Katerina , Blazhevska Aleksandra , Stojanovska Marina
Published: April 2022

The Nearpod software application was implemented in chemistry teaching, thus keeping in touch with current technology appropriate for its use in the education. This is the first study in our country focusing on the usage of the Nearpod as an e-module-based learning media aimed to increasing students’ motivation in chemistry classes, through their engagement during the lesson and active participation. The total sample consisted of 244 9th grade students and 7 teachers from 7 primary schools. This research was based on data collection by modified SMTSL and IMI questionnaires and individual interviews with students and teachers. The data were analyzed and the mean, standard deviation and Cronbach’ alpha reliability coefficient were calculated, which revealed acceptable internal consistency for all subscales. Data obtained from the APQ-N instrument showed that most of the students found this activity enjoyable and interesting, and felt that it was important for their success and progress, but it also enabled them to achieve better results and improve their attention during the online classes. SMTSL-N questionnaire revealed that the students had medium motivation toward chemistry leaning overall. Independent t-tests results stated that there is no significant difference between male and female students’ mean scores. The results obtained in this study, including the interview data as well, indicated that Nearpod-based activities positively influenced students’ motivation in learning chemistry. Nearpod has a great potential to be applied during the face-to-face teaching as a hybrid model in the future, thus making teaching more interesting and less monotonous.
Tracing the bongkel: bamboo music of rural farmers in Banyumas, Central Java, Indonesia
Authors: Kuwat Kuwat
Published: April 2022

Bongkel is the music of a farming community that developed in Gerduren Village, Purwajati, Banyumas, Central Java. This music only uses a four-tone slendro tuning. The current condition is that it is very difficult to find bongkel players; if there is no tracking of information about the history of bongkel, then in the future, it will be very difficult to find important information about bongkel. The purpose of this research is to trace and document the bongkel, from the side of its early history to its musicological review. The research method used is observation and interviews to explore oral sources. The use of oral sources is done because, until now have never received written data that specifically discusses bamboo music, especially in the Banyumas language. The interview focused on Kasmudi, Ibu Kunes, Maryadi Kresek and several other informants who were selected as sources, especially Kasmudi (a bongkel player) because he was the perpetrator the main witness. Kasmudi is the fourth generation of his entire family, which is a bongkel player on average. There are three types of data analyzed, including the history of the appearance of the bongkel, organology data, and musicological data. The grouping of data is done based on the three types of data, and the analysis is done by referring to the grouping of the three types of data. The results of this study found that the strongest characteristic of bongkel music is the imbal technique; besides that, bongkel is one of the musical instruments that became the forerunner to the development of angklung buncis, krumpyung, and calung music. The contribution of this research provides important information for the interest of Banyumas musical studies, especially for the development of bamboo music
Лінійна, квадратурна та кубатурна геометрична інтерпретація числових рядів засобами моделювання
Authors: Корольський Володимир Вікторович , Габ Світлана Сергіївна
Published: April 2022

Метою дослідження є геометрична інтерпретація числових рядів, побудова моделі геометричної інтерпретації числових рядів в середовищі програмування, отримання розрахунків для лінійної, квадратурної та кубатурної геометричної інтерпретації числових рядів. Задачами дослідження є розгляд питання про необхідність геометричної інтерпретації об’єктів у навчанні природничо-математичних дисциплін, зокрема числових рядів у рамках дисципліни «Математичний аналіз»; розкриття змісту таких понять, як «модель», «моделювання», побудова моделі числових рядів у середовищі програмування; виконання обчислення для знайдених числових рядів за допомогою електронних таблиць. Об’єктом дослідження є геометрична інтерпретація числових рядів. Предметом дослідження є використання мови програмування та електронних таблиць для моделювання та аналізу отриманих результатів числових рядів з лінійною, квадратурною та кубатурною геометричною інтерпретацією. Методами дослідження є евристичний пошук знакових моделей числових рядів за допомогою моделей певних геометричних об’єктів. Результати дослідженнями планується узагальнити в методичній розробці з теми «Числові ряди».