bluuebunny/crossref_metadata_2025 huggingface dataset:
Recycled Construction and Demolition Waste as Supplementary Cementing Materials in Eco-Friendly Concrete
Authors: Zito Silvina V. , Irassar Edgardo F. , Rahhal Viviana F.
Published: June 2023

Growing environmental awareness and scarcity of natural resources are forcing the world to migrate from linear to circular economies. The possibility of partially replacing cement with ceramic-based waste from construction and demolition waste (C&DW) is a government and industry focus. The present study analyzes the effects of including finely ground complete walls of ceramic blocks (including masonry mortars) as supplementary cementing materials (SCM) on the physical, mechanical, and transport properties (water absorption and permeability) of concrete. The replacement ratio employed was 25% by weight of cement. Studies of the hydration evolution of cement pastes support the described properties of concretes. The findings reveal that the ground ceramic-based waste from C&DW stimulates hydration at all ages. Initially, this stimulation is predominantly physical (filler effect), but in later stages, it becomes chemical (pozzolanic reaction). Based on the results obtained in this study, it is possible to produce concrete with mechanical properties comparable to those of conventional concrete at 28 days.
Design and Performance Analysis of a Torsional Soft Actuator Based on Hyperelastic Materials
Authors: Xu Zhengyun , Liu Haiqiang , Feng Weihua , Yang Huaming , Nie Xin , Zhou Rougang
Published: June 2023

Conducting research on soft robots is crucial as there are still many problems that need to be resolved in the areas of material selection, structure design and manufacture, and drive control. Soft manipulators, a subset of soft robots, are now a popular area of study for many researchers. In comparison to typical manipulators, soft manipulators feature a high degree of gripping flexibility and a basic morphological structure. They are composed of flexible materials. They have a wide range of potential applications in healthcare, rehabilitation, bionics, and detection, and they can compensate for the drawbacks of rigid manipulators in some use scenarios. A modular soft-body torsional gripping system is developed after a torsional and gripping actuator is conceived and constructed, and its performance examined. The torsion actuator and the grasping actuator can be combined in the system in a modular fashion. With the help of RGB-D vision algorithms, this multi-modular setup makes it possible to combine soft actuators with various twisting degrees and achieve exact gripping. Through pneumatic control, the target object is precisely grasped and rotated at various angles, enabling the rotation of the target object in three dimensions.
The Self-Disproportionation of Enantiomers (SDE) of α-Pinene via Evaporation off Silica Gel and Foam Fractionation—Validation of the Plausibility of SDE via Gas Chromatography (GC) for α-Pinene
Authors: Wzorek Alicja , Soloshonok Vadim A. , Klika Karel D.
Published: June 2023

α-Pinene is an intriguing monoterpene as it has been reported to undergo the self-disproportionation of enantiomers (SDE) phenomenon via gas chromatography (GC), the only compound to decisively demonstrate this. Examples of the SDE involving the gaseous phase—sublimation aside—are extremely rare. Attempts to replicate the GC results were unsuccessful, though the authors argued convincingly for the difficulty of observing the phenomenon. However, we could effect for α-pinene SDE via evaporation off silica gel and by foam fractionation—albeit the SDE magnitude for both was only very slight—to confirm that α-pinene can undergo the SDE for processes involving a gaseous phase and thus validate the plausibility of the GC report. The indications are that the molecular associations responsible for the various SDE observations of α-pinene occur not in the gaseous phase or the bulk phase but rather in two-dimensional (2D) adsorbed monolayers and are not based on conventional functional group-based intermolecular interactions and instead are, most likely, as a result of homo- and heterochiral packing differences in the 2D monolayers—a well-known 2D chiral-based association packing effect. These are also the first reports of the occurrence of the SDE using an adsorptive bubble separation process (foam fractionation) and involving a gaseous phase other than sublimation, GC, and distillation.
Men’s Physical Attractiveness Predicts Women’s Ratings of Sexual Intent through Sexual Arousal: Implications for Sexual (Mis)Communication
Authors: Livingston Tyler N. , Rerick Peter O.
Published: June 2023

Men often perceive greater sexual willingness underlying women’s behaviors than women themselves intend. This discrepancy can contribute to sexual miscommunication and, sometimes, acts of sexual assault. The current study tested whether actor–observer asymmetry is present in women’s ratings of sexual intent to offer an additional explanation for past findings. We hypothesized that women rating their own behaviors would report less sexual intent compared to women rating another woman’s behaviors. We also hypothesized that these ratings would be influenced by the physical attractiveness of a male target through self-reported sexual arousal as a mediation pathway. Results from a community sample of 164 women (Mage = 42 years) generally supported these hypotheses. Sexual arousal was positively associated with ratings among all participants, but the mediation pathway was significant only for women rating another woman’s behavior. The findings suggested that actor–observer asymmetry is present in ratings of sexual intent. This effect might account for some of the sexual overperception phenomena and explain why third-party observers of women’s sexual behavior (e.g., potential partners, Title IX investigators, jurors) sometimes misinterpret sexual willingness.
Effect of Outdoor Leisure Activity Participation on Leisure Attitude, Serious Leisure, Recreational Specialization, and Leisure Satisfaction
Authors: Song Won-Ick , Ahn Byoung-Wook
Published: June 2023

Due to the recent COVID-19 pandemic, there has been a tendency for people to participate more frequently in outdoor leisure activities as opposed to indoor leisure activities. Leisure activities bestow various benefits. The purpose of this research is to study the effect of leisure attitude, serious leisure, recreational specialization, and leisure satisfaction among outdoor leisure activity participants in South Korea. Therefore, this research is used to analyze the relationships amongst leisure attitudes, serious leisure, recreational specialization, and leisure satisfaction among various theories about leisure. The participants in this study were collected from amongst 356 people who were frequent participants in outdoor leisure activities. For the data analysis, we used frequency, confirmatory analysis, reliability, correlation, and structural equaling modeling. The findings are as follows. First, leisure attitude had an influence on serious leisure and leisure satisfaction. Second, serious leisure had an effect on recreational specialization and leisure satisfaction. Third, recreational specialization had an influence on leisure satisfaction. According to the results of this study, leisure attitude and recreational specialization had insignificant effects, but all other hypotheses were accepted. Despite the COVID-19 pandemic, it was various reasons such as, leisure attitude, serious leisure, recreational specialization, leisure satisfaction and which was continuous participation in outdoor leisure activities were confirmed in South Korea.
Melatonin Ameliorates Apoptosis of A549 Cells Exposed to Chicken House PM2.5: A Novel Insight in Poultry Production
Authors: Dai Pengyuan , Shen Jiakun , Shen Dan , Li Xiaotong , Win-Shwe Tin-Tin , Li Chunmei
Published: June 2023

The particulate matter 2.5 (PM2.5) from the chicken production system can cause lung injury and reduce productivity through prolonged breath as it attaches large amounts of harmful substances and microbes. Melatonin has acted to regulate physiological and metabolic disorders and improve growth performance during poultry production. This research would investigate the apoptosis caused by chicken house PM2.5 on lung pulmonary epithelial cells and the protective action of melatonin. Here, the basal epithelial cells of human lung adenocarcinoma (A549 cells) were subjected to PM2.5 from the broiler breeding house to investigate the apoptosis induced by PM2.5 as well as the alleviation of melatonin. The apoptosis was aggravated by PM2.5 (12.5 and 25 μg/mL) substantially, and the expression of Bcl-2, Bad, Bax, PERK, and CHOP increased dramatically after PM2.5 treatment. Additionally, the up-regulation of cleaved caspase-9 and cleaved caspase-3 as well as endoplasmic reticulum stress (ERS)-related proteins, including ATF6 and CHOP, was observed due to PM2.5 exposure. It is worth noting that melatonin could support A549 cells’ survival, in which reduced expression of Bax, Bad, cleaved caspase-3, and cleaved caspase-9 appeared. Concurrently, the level of malondialdehyde (MDA) was down-regulated and enhanced the intracellular content of total superoxide dismutase (T-SOD) and catalase (CAT) after treatment by PM2.5 together with melatonin. Collectively, our study underlined that melatonin exerted an anti-apoptotic action on A549 cells by strengthening their antioxidant capacity.
Optimized Derivation of Predicted No-Effect Concentrations (PNECs) for Eight Polycyclic Aromatic Hydrocarbons (PAHs) Using HC10 Based on Acute Toxicity Data
Authors: Sun Xiao , Ding Ting-Ting , Wang Ze-Jun , Huang Peng , Liu Shu-Shen
Published: June 2023

For persistent organic pollutants, a concern of environmental supervision, predicted no-effect concentrations (PNECs) are often used in ecological risk assessment, which is commonly derived from the hazardous concentration of 5% (HC5) of the species sensitivity distribution (SSD). To address the problem of a lack of toxicity data, the objectives of this study are to propose and apply two improvement ideas for SSD application, taking polycyclic aromatic hydrocarbons (PAHs) as an example: whether the chronic PNEC can be derived from the acute SSD curve; whether the PNEC may be calculated by HC10 to avoid solely statistical extrapolation. In this study, the acute SSD curves for eight PAHs and the chronic SSD curves for three PAHs were constructed. The quantity relationship of HC5s between the acute and chronic SSD curves was explored, and the value of the assessment factor when using HC10 to calculate PNEC was derived. The results showed that, for PAHs, the chronic PNEC can be estimated by multiplying the acute PNEC by 0.1, and the value of the assessment factor corresponding to HC10 is 10. For acenaphthene, anthracene, benzo[a]pyrene, fluoranthene, fluorene, naphthalene, phenanthrene, and pyrene, the chronic PNECs based on the acute HC10s were 0.8120, 0.008925, 0.005202, 0.07602, 2.328, 12.75, 0.5731, and 0.05360 μg/L, respectively.
Theracurmin Modulates Cardiac Inflammation in Experimental Model of Trypanosoma cruzi Infection
Authors: Louise Vitória , Machado Bianca Alves Almeida , Pontes Washington Martins , Menezes Tatiana Prata , Dias Fernanda Carolina Ribeiro , Ervilhas Luiz Otávio Guimarães , Pinto Kelerson Mauro de Castro , Talvani André
Published: June 2023

Theracurmin is a nanoparticle formulation derived from curcumin, a bioactive compound known for its antioxidant and anti-inflammatory properties. Trypanosoma cruzi, the etiological agent of Chagas disease, triggers an intense inflammatory response in mammals and also causes severe tissue damage. To evaluate the immunomodulatory and antiparasitic effects of Theracurmin, Swiss mice were experimentally infected with 103 trypomastigote forms of the Colombian strain of T. cruzi and submitted to daily therapy with 30 mg/kg of Theracurmin. In addition, daily benznidazole therapy (100 mg/kg) was performed as a positive control. We evaluated the systemic and tissue parasitism, the survival and the body mass rate, the release of inflammatory mediators (TNF, IL-6, IL-15, CCL2 and creatine kinase) and the tissue inflammation at day 30 post-infection. Theracurmin therapy reduced the parasitemia curve without altering the animals’ survival rate, and it protected mice from losing body mass. Theracurmin also reduced CCL2 in cardiac tissue, IL-15 in cardiac and skeletal tissue, and plasma CK. Even without effects on TNF and IL-6 production and tissue amastigote nests, Theracurmin reduced the leukocyte infiltrate in both evaluated tissues, even in the case of more effective results observed to the benznidazole treatment. Our data suggest Theracurmin has an immunomodulatory (CCL2, IL-15, CK and tissue leukocyte infiltration) and a trypanocidal effect (on circulating parasites) during experimental infection triggered by the Colombian strain of T. cruzi. Further investigations are necessary to comprehend the Theracurmin role performed in combination with benznidazole or other potential anti-T. cruzi chemical compounds.
Analytical Constraints on the Radius and Bulk Lorentz Factor in the Lepto-Hadronic One-Zone Model of BL Lacs
Authors: Ma Zhi-Peng , Wang Kai
Published: June 2023

In this work, we study the parameter space of neutrino-emitting BL Lacs under the framework of the one-zone lepto-hadronic model. We show that constraints on the model come from various aspects of observations such as the variability timescale of blazar flares, gamma ray opacity and the spectral energy distribution of electromagnetic emission, as well as the inferred neutrino emissivity of the blazar. We apply our method to two potential neutrino sources, i.e., TXS 0506+056 and PKS 0735+178, which are BL Lacs. Then, we explore and summarize the allowed range of parameters such as the bulk Lorentz factor and the blob radius under different distributions of injected protons. We find that the parameter space that is available to explain the BL Lac–neutrino association is sensitive to the proton distribution, and usually, an injected proton luminosity significantly exceeding the Eddington luminosity is required for both sources. Our results suggest that the simple lepto-hadronic one-zone model may not be a reasonable interpretation for BL Lac–neutrino associations.
Development and Optimal Immune Strategy of an Alum-Stabilized Pickering emulsion for Cancer Vaccines
Authors: Peng Sha , Yan Yumeng , Ngai To , Li Jianjun , Ogino Kenji , Xia Yufei
Published: June 2023

Therapeutic cancer vaccines are considered as one of the most cost-effective ways to eliminate cancer cells. Although many efforts have been invested into improving their therapeutic effect, transient maturation and activations of dendritic cells (DCs) cause weak responses and hamper the subsequent T cell responses. Here, we report on an alum-stabilized Pickering emulsion (APE) that can load a high number of antigens and continue to release them for extensive maturation and activations of antigen-presenting cells (APCs). After two vaccinations, APE/OVA induced both IFN-γ-secreting T cells (Th1) and IL-4-secreting T cells (Th2), generating effector CD8+ T cells against tumor growth. Additionally, although they boosted the cellular immune responses in the spleen, we found that multiple administrations of cancer vaccines (three or four times in 3-day intervals) may increase the immunosuppression with more PD-1+ CD8+ and LAG-3+ CD8+ T cells within the tumor environment, leading to the diminished overall anti-tumor efficacy. Combining this with anti-PD-1 antibodies evidently hindered the suppressive effect of multiple vaccine administrations, leading to the amplified tumor regression in B16-OVA-bearing mice.
The Prevalence of Multidrug-Resistant Acinetobacter baumannii and Its Vaccination Status among Healthcare Providers
Authors: Elbehiry Ayman , Marzouk Eman , Moussa Ihab , Mushayt Yazeed , Algarni Ahmad Abdullah , Alrashed Osama Ali , Alghamdi Khalid Saad , Almutairi Naif Ahmed , Anagreyyah Sulaiman Abdulaziz , Alzahrani Anwar , Almuzaini Abdulaziz M. , Alzaben Feras , Alotaibi Meshal Abdullah , Anjiria Suha Abdulaziz , Abu-Okail Akram , Abalkhail Adil
Published: June 2023

There is growing concern among healthcare providers worldwide regarding the prevalence of multidrug-resistant Acinetobacter baumannii (A. baumannii). Some of the worst hospital-acquired infections, often in intensive care units (ICUs), are caused by this bacterial pathogen. In recent years, the rise in multidrug-resistant A. baumannii has been linked to the overuse of antimicrobial drugs and the lack of adequate infection control measures. Infections caused by this bacterial pathogen are the result of prolonged hospitalization and ICU stays, and they are associated with increased morbidity and mortality. This review outlines the epidemiology, risk factors, and antimicrobial resistance associated with A. baumannii in various countries, with a special focus on the Kingdom of Saudi Arabia. In response to the growing concern regarding this drug-resistant bacteria, fundamental information about its pathology has been incorporated into the development of vaccines. Although these vaccines have been successful in animal models, their effectiveness in humans remains unproven. The review will discuss the development of A. baumannii vaccines, potential related obstacles, and efforts to find an effective strategy against this pathogen.
Computed Tomographic Features of Thymus in Dogs: Correlation with Age, Gender, Breed and Body Fat Content
Authors: Molazem Mohammad , Soroori Sarang , Bahonar Alireza , Karimi Saghar
Published: June 2023

Background: The thymus is the first lymphoid organ formed to regulate a newborn’s immunity. It reaches its maximum size during puberty, after which it undergoes an atrophic procedure called involution, but its ability to grow again in response to some stresses, such as infections, neoplasia, surgeries, chemotherapy, and radiotherapy is maintained. There is no comprehensive study on computed tomographic features of thymus in dogs. So, the goal of the present study is to gain better insight into the thymus using computed tomography as a non-invasive method. Methods: One hundred and fifty dogs classified in five age groups and five breed groups were recruited to this study and the thymus was evaluated using a 2-slice computed tomography machine. The inclusion criteria for the present study were having a normal complete blood count, plain and post-contrast CT scan examination of the thoracic region and no history of neoplasia, chemotherapy or radiotherapy. The visibility, density, enhancement, grade, size, volume, shape, borders and lateralization of the thymus were evaluated and statistical analysis was performed. The effect of obesity on thymic grade and volume was also investigated. Results: The visibility, density, dorsal length, volume and grade decreased with increasing age. The thymic shape and lateralization were mostly wedge shaped and left sided, respectively. The borders became concave with aging and increasing body fat content caused an increase in the fatty degeneration of the thymus. Conclusions: Declining thymic density, grade, size and volume with aging are related to thymic involution and fatty degeneration was accelerated by increasing body fat content. Females and males were different only in thymic shape and small and large breeds were different only in thymic volume. The thymus was visible in some geriatric dogs with no underlying disease. We expect that the present work can be used by radiologists in reading thoracic computed tomography but investigation of thymic characteristics in dogs with neoplasia and history of chemotherapy, radiotherapy and thoracic surgeries can complete this study.
Chandelier-Assisted Scleral Buckling: A Literature Review
Authors: Governatori Lorenzo , Scampoli Alessandra , Culiersi Carola , Bernardinelli Patrizio , Picardi Stefano Maria , Sarati Federica , Caporossi Tomaso
Published: June 2023

The treatment of retinal detachment (RD) has seen numerous advancements in the last decades. Scleral buckling (SB) is a surgical procedure introduced in the 1950s that has seen a drastic reduction with the advent of vitrectomy. However, due to the new surgical visualization systems, SB has evolved and continues to be an extremely useful procedure in certain conditions. The presence of different case reports or interventional studies with comparable outcomes, as well as the lack of recent studies with direct comparison, may result in an underestimation of its potential nowadays. The aim of this review is to provide a comprehensive update on chandelier-assisted scleral bucking (CSB), with an overview of the surgical evolution, outcomes, advantages, and complications.
Elaboración de un preparado hidrosoluble en forma de sólido pulverulento a partir de Ilex guayusa Loes.
Authors: Luna Fox Sting Brayan , Álvarez Castro Reinaldo Rigoberto , Peñafiel-Bonilla Nelly Jazmín , Radice Matteo , Scalvenzi Laura , Arteaga Crespo Yasiel , López Hernández Orestes Darío , Bravo Sánchez Luis Ramón
Published: June 2023

La investigación tuvo como objetivo elaborar un preparado hidrosoluble en forma de sólido pulverulento a partir del extracto acuoso de Ilex guayusa Loes, para el que se consideró prioritario maximizar el contenido de cafeína y polifenoles. Las mejores condiciones para extraer la mayor cantidad de cafeína y polifenoles fueron con 15 g de guayusa en 100 mL de agua destilada, aplicando la decocción por 30 min. Mediante métodos espectrofotométricos se cuantificó la cantidad de cafeína y de polifenoles totales, las cuales arrojaron valores de 71.7 mg/L y 55.76 mg/L respectivamente. Se aplicó la tecnología de spray drying para obtener muestras de sólido pulverulento hidrosoluble. Sobre estas muestras se realizaron pruebas de solubilidad, y dio como resultado un tiempo de disolución en caliente (ebullición) menor a 30 segundos y en frío (16°C ± 2°C) menor a 3 min. El valor de pH, y contenido de cenizas totales fueron 5.50 y 13.87%, respectivamente. Las muestras del sólido pulverulento resultaron libres de microorganismos aerobios mesófilos. El contenido de cobre, zinc y hierro fue de 12.35 mg/kg, 234.50 mg/kg y 19.35 mg/kg correspondientemente; el plomo resultó ser no detectable en las muestras. Los resultados obtenidos son coherentes con la normativa NTE INEN 1122:2013 relacionada a los requisitos de café soluble obtenido por spray drying. La presente investigación sienta las bases para el desarrollo industrial de un producto hidrosoluble a base de extracto de I. guayusa rico en cafeína y polifenoles.
GP assessment of unmet need in a complex multimorbid population using a data-driven and clinical triage system: a prospective cohort study
Authors: Parry Emma , Ahmed Kamran , Evans Simon , Guest Elizabeth , Klaire Vijay , Koodaruth Abdool , Labutale Prasadika , Matthews Dawn , Lampitt Jonathan , Pickavance Gillian , Sidhu Mona , Warren Kate , Singh Baldev
Published: June 2023

Background

Patients with unmet healthcare needs are more likely to access unscheduled care. Identifying these patients through data-driven and clinical risk stratification for active case management in primary care can help address patient need and reduce demand on acute services.

Aim

To determine how a proactive digital healthcare system can be used to undertake comprehensive needs analysis of patients at risk of unplanned admission and mortality.

Design & setting

Prospective cohort study of six general practices in a deprived UK city.

Method

To identify those with unmet needs, the study’s population underwent digitally-driven risk stratification into Escalated and Non-escalated groups using seven risk factors. The Escalated group underwent further stratification using GP clinical assessment into Concern and No concern groups. The Concern group underwent Unmet Needs Analysis (UNA).

Results

From 24 746 patients, 516 (2.1%) were triaged into the Concern group and 164 (0.7%) underwent UNA. These patients were more likely to be older (t= 4.69,P<0.001), female (X2= 4.46,P<0.05), have a Patients At Risk of Re-hospitalisation (PARR) score ≥80 (X2= 4.31,P<0.05), be a nursing home resident (X2= 6.75,P<0.01), or on an end-of-life (EOL) register (X2= 14.55,P<0.001). Following UNA, 143 (87.2%) patients had further review planned or were referred for further input. The majority of patients had four domains of need. In those who GPs would not be surprised if they died within the next few months,n= 69 (42.1%) were not on an EOL register.

Conclusion

This study showed how an integrated, patient-centred, digital care system working with GPs can highlight and implement resources to address the escalating care needs of complex individuals.
Multidisciplined student projects: A systems case study, leading to a regenerative implementation strategy
Authors:   , William Maynard Early
Published: June 2023

This thesis is a systems level evaluation of the multi-disciplined project (the electric vehicle design and build by students). The study looked at the immediate systems surrounding the build project, and identified some key systems: Capital (values), Knowledge, Core competence, Promotion, Student development. This led to the identification of a key weakness in the build project, student numbers. With the Covid 19 disruption in 2020, a further systems review looking at global issues, led to some solutions based around regenerative thinking principles. The most appealing ongoing approach to multidisciplined projects is to have them based on: Staff centered research in areas where research is already taking place and have high student numbers; Develop projects that require wider input from multiple disciplines; Utilize postgraduate and undergraduate students in appropriate level sub-project research. Looking at the surrounding systems and influences, leads to a deeper understanding of the problem, and to the issues resulting from a possible solution. The initial study looked from the inside out, mostly revealing the immediate environment of the build project. The second study started much wider, looking from outside in. This revealed trends that are happening globally, the issues they cause, and how better decisions can be made for local problems understanding global issues. The solution coming from the second study has a far better understanding of the problem from a systems perspective and has led to a far more considered solution. This systems approach is transferable to any project and is likely to enable better decisions based on better understandings of immediate and global issues. Using a systems level evaluation of the build project has led to a proposed solution that considers both immediate and global issues, leading to a solution that: Is centered in departments already rich in research; Potentially produces great staff and student outcomes; Expands the research activity in the polytechnic; Is truly multidisciplinary; Is ongoing; A systems level approach leads to better understandings of problems, which leads to better decision making. Framing what a good solution would be can only come from a well-informed educated background, and the principles of regenerative thinking provide this. Addressing future issues using a system based regenerative framework should lead to better solutions for people and the planet in future.
Factors Influencing on Nursing Profession of Nursing Students in the Post-Corona Era
Authors:   Korean Society of Nursing Research, Jo A Young , Je Nam Joo
Published: June 2023

Purpose : This study aimed to investigate the effects of academic stress, ego-resilience, and grit on the perceptions of the nursing profession among nursing students who have undergone clinical training following the COVID-19 pandemic outbreak.
Method : Employing a descriptive research design, data were collected from 177 nursing students across three universities in City C, Gyengsangnam-do between October 11 and October 17, 2022. The gathered data were analyzed using IBM SPSS/WIN 21.0.
Results : The factors significantly influencing participants’ perceptions of the nursing profession included ego-resilience (β＝.404), being a junior student (β＝.206), and the intention to work as a nursing practitioner in a hospital setting upon graduation (β ＝.192), The combined explanatory power of these variables was 37.2% (F＝9.01, p＜.001, R2＝.418, Adj. R2 ＝.372).
Conclusion : The findings underscore the importance of fostering ego-resilience and enhancing understanding of the nursing profession through a systematic curriculum in the post-COVID-19 era. Establishing an accurate perception of the nursing profession will aid nursing students in improving their professional competency and commitment.
A High-Performance MoS
2
-Based Visible–Near-Infrared Photodetector from Gateless Photogating Effect Induced by Nickel Nanoparticles
Authors: Duan Ran , Qi Weihong , Li Panke , Tang Kewei , Ru Guoliang , Liu Weimin
Published: June 2023

Recent advancements in two-dimensional materials have shown huge potential for optoelectronic applications. It is challenging to achieve highly effective and sensitive broadband photodetection based on MoS
2
devices. Defect engineering, such as introducing vacancies, can narrow the bandgap and boost the separation of photogenerated carriers by defect states but leads to a slow response speed. Herein, we propose a nickel nanoparticle-induced gateless photogating effect with a unique energy band structure to enable the application of defect engineering and achieve high optoelectronic performance. The device based on Ni nanoparticle-decorated MoS
2
with S vacancies exhibited high responsivities of 106.21 and 1.38 A W
−1
and detectivities of 1.9 × 10
12
and 8.9 × 10
9
Jones under 532 and 980 nm illumination (visible to near infrared), respectively, with highly accelerated response speed. This strategy provides new insight into optimizing defect engineering to design high-performance optoelectronic devices capable of broadband photodetection.
Cladribina para el tratamiento de la esclerosis múltiple remitente recurrente: nueva alternativa para Latinoamérica
Authors: Rito Yamel , Rivas-Alonso Verónica , Chiquete Erwin
Published: June 2023

Cladribine is a modified deoxyadenosine that evades the action of the enzyme adenosine deaminase, which results in an immunosuppressive effect through lymphopenia, leading to an immune cells reconstitution that helps in the treatment of autoimmune diseases such as relapsing–remitting multiple sclerosis (RRMS). Since we currently have a wide range of medications to treat RRMS, it is of great interest to identify the role that cladribine plays among all options. The main objective of this narrative review is to provide useful information, with the aid of a clinical case study, which helps physicians in making decisions to treat patients with RRMS, and provide them with the best options for efficacy and safety. Due to its selective immunosuppressive effects, cladribine is indicated for the treatment of moderate to severe activity RRMS, either in escalation therapy or as induction therapy. In this article we will also analyze the characteristics of this drug to establish the scientific bases that guide the therapeutic decision making, taking into account the balance of risks and benefits for the patient.
Pengaruh Lokasi, Fasilitas dan Kepuasan Wisatawan Terhadap Keputusan Berkunjung Kembali
Authors: Lestari Anggia Ayu , Yuliviona Reni , Liantifa Melifia
Published: June 2023

This study aims to examine how much influence the Location, Facilities and Tourist Satisfaction have on the Decision to Visit Again at the Bukit Khayangan Tourism Object, Sungai Full City. The background of this research is the decrease in the number of tourists visiting the Bukit Khayangan Tourism Object, Sungai Full City. The population used in this study were tourists at the Bukit Khayangan Tourism Object, Sungai Full City. Data collection was carried out using a questionnaire with a total sample of 80 respondents who visited the Bukit Khayangan Tourism Object, Sungai Full City. This research method uses a non-probability sampling technique with the accidental sampling technique method. The data obtained from the questionnaire, then processed and analyzed using multiple linear regression analysis through SPSS software. The results showed that there was a significant and positive influence between Location on the Decision to Visit at the Bukit Khayangan Tourism Object, Sungai Full City, There was a significant and positive influence between Facilities on the Decision to Visit at the Bukit Khayangan Tourism Object, Sungai Full City, there was a significant influence between satisfaction tourists with the decision to return to the Bukit Khayangan tourist attraction, Sungai Full City and there is a significant and positive influence between Location, Facilities and Tourist Satisfaction on the Decision to Visit again at the Bukit Khayangan Tourism Object, Sungai Full City.
General physical training of cadets in educational organisations of the Ministry of Internal Affairs of Russia
Authors: Kulikov Mikhail , Naumenko Stanislav
Published: June 2023

Introduction. Good physical fitness is an important component of human health and the basis of high professional performance. For a police officer, physical training is not only a means of keeping and maintaining good health, energy and high efficiency, but also an essential element of service activity, which involves the use of physical force and combat fighting techniques. The very process of mastering fighting techniques, forming the necessary motor skills and abilities and their further improvement proceeds much more successfully on the background of a high level of general physical fitness. The relevance of the researchconsists in the high importance of general physical training, which is the foundation of all professional-applied training of cadets and trainees, contributing to the formation of necessary knowledge and skills to organise their life in accordance with socially significant ideas about healthy lifestyles, as well as the ability to independently maintain the necessary level of physical fitness for full professional activity.

Research methods. Analysis of documents regulating the educational activities of cadets and trainees in physical training in educational organisations of the Ministry of Internal Affairs of Russia, survey of specialists giving practical courses in the discipline «Physical training», study of changes in testing indicators of general physical training of cadets, methods of mathematical statistics.

Results. The authors have studied regulatory documents, experts’ opinions, examined the dynamics of changes in the level of general physical fitness of cadets of St. Petersburg University of the Ministry of Internal Affairs of Russia based on the results of control standards. Both absolute indices and indices, expressed in points, have been investigated. On the basis of the carried out researches measures of further increase of efficiency of the general physical training of students in educational organisations of the system of the Ministry of Internal Affairs of Russia are defined.
Kształtowanie kompetencji społeczno-emocjonalnych dzieci w młodszym wieku szkolnym z wykorzystaniem programu Good Behavior Game (Gra w Dobre ZachowaniA)
Authors: Kwatera Anna
Published: June 2023

Znaczącym celem współczesnej edukacji realizowanej zarówno formalnie, jak i nieformalnie na każdym etapie rozwoju człowieka jest przygotowanie go lub zwiększenie poziomu adaptacji do samodzielnego funkcjonowania w społeczeństwie. Opiera się ono na ukształtowaniu kluczowych kompetencji (twardych i miękkich) uwzględniających komponenty wiedzy, umiejętności i doświadczenia. Im wcześniej rozpocznie się ich kształtowanie, tym lepsze efekty przyniesie nabywanie przez uczniów społecznie oczekiwanych zachowań i postaw. W artykule zarysowano kontekst realizacji amerykańskiego programu Good Behawior Game (GBG), w polskich szkołach implementowanego jako Gra w Dobre ZachowaniA (GDZ), jego główne założenia i metodykę stosowania. Wskazano również na te obszary jego skuteczności, które odnoszą się do sposobów kształtowania różnych aspektów społeczno-emocjonalnego funkcjonowania dziecka na progu jego drogi edukacyjnej. Program GBG realizowany w szkołach podstawowych, wpisany na listę programów rekomendowanych przez PARPA[1], zalicza się do tej kategorii działań wspierających edukację, które zdecydowanie ułatwiają kształtowanie zestawu kompetencji stanowiących treść oczekiwanych postaw. Dla dzieci rozpoczynających szkołę GBG/GDZ stanowi ułatwienie odnalezienia się w roli ucznia, dla nauczyciela jest sprawdzonym narzędziem do efektywnego zarządzania zachowaniem w klasie, a w kontekście długofalowym pozwala zredukować częstotliwość zachowań ryzykownych u późniejszych adolescentów i młodych dorosłych.

 

[1] Z dn. 1.01.2022 r. na mocy ustawy z dn. 17 grudnia 2021 r. o zmianie ustawy o zdrowiu publicznym oraz niektórych innych ustaw (Dz. U. 2021, poz. 2469) Krajowe Biuro do Spraw Przeciwdziałania Narkomanii i Państwowa Agencja Rozwiązywania Problemów Alkoholowych zostają przekształcone w Krajowe Centrum Przeciwdziałania Uzależnieniom (Jabłoński, 2021).
Edytorial: Cielesność i podmiot
Authors: Walczak Anna
Published: June 2023

We współczesnym dyskursie humanistyczno-społecznym pytania o ciało i cielesność zaczynają stopniowo wyprzedzać pytania o podmiot i jego tożsamość badane z perspektywy „zastanych” paradygmatów. Także dotychczasowe wypowiedzi o podmiocie w-cielonym lub ucieleśnionym coraz częściej poddawane są krytyce. Współczesne podejścia do ciała i cielesności przestawiają zwrotnicę w narracjach o podmiotowości, podmiocie i jego tożsamości, która – zapośredniczona w ciele i cielesności – tworzy się w cyklach życia, jak i w doświadczeniach granicznych, w wyniku których doświadcza się zmian somatycznych, przeżyć kryzysowych, traumy itp.
Embodiment in Old Age
Authors: Muszyński Marcin
Published: June 2023

RESEARCH OBJECTIVE: This article presents embodiment in relation to four areas of human agency. The findings are part of a larger project on learning to be old.

THE PROBLEM AND RESEARCH METHODS: The main research problem is understanding how strategies, actions, and attitudes toward one’s body differ among the study participants in various agency areas. The study is based on a constructivist paradigm and grounded theory methodology.

THE PROCESS OF ARGUMENTATION: Four fields of the agency have been presented on a continuum, where on one side, forces are pushing a person towards dependence, while on the other side, there is the individual’s independence. These areas were identified during the analysis of empirical data and allow for a departure from judgmental approaches to aging, serving as model areas for the functioning of an older adult . These areas were used to reflect on the embodiment of older people. Finally, the embodiment category was placed within broader structures such as discourses, concepts, and theoretical knowledge about aging and getting old.

RESEARCH RESULTS: The findings indicate the multidimensional nature of the aging body. Different strategies, actions, and attitudes towards one’s embodiment are activated depending on the individual’s life situation and social position.

CONCLUSIONS, INNOVATIONS, AND RECOMMENDATIONS: Embodiment occupies a special place in learning to be old. It is one of the primary regulators of this process. As it turns out, self-identification is primarily related to the body. Furthermore, the findings of this study allow moving away from a narrow understanding of aging as physical deterioration and decay.
Routine, tact, and disciple as components of the subject’s identity in the context of its corporeality
Authors: Drabarek Anna
Published: June 2023

RESEARCH OBJECTIVE : Deliberations on identity of the subject first of allrefer to difficulties in trying to define to notion itself and the identity of the subject in the context of his corporeality.
THE RESEARCH PROBLEMS AND METHODS: The literature analysis method. The word identity may be defined as identicality  at a given time and place . The problem of identity is analyzed  on the social plan.
THE PROCESS OF ARGUMENTATION: The text presents the definitions of the concepts used, the theoretical foundations and historical outline. 
RESEARCH RESULTS: When describing the identity of a subject from the socjological, psychological and biological perspective, we come to the conclusion that while the brain is responsible for our mental life, it is neither the only nor sufficient condition of awareness and self-awareness. It is pointed out that the features which constitute identity are rationality, self-awareness, coherence and stability. The problem of identity analyzed on the narrative, linguistic and social plane also calls for assertions made on the ethical plane. The contemporary discourse on identity most often emphasizes its changeability, instability, and its Protean nature.
CONCLUSIONS, INNOVATIONS AND RECOMRNDATIONS: In the analyzes presented in this article, the concept of identification is emphasized, replacing the word identity, because it is more operational and coexists with the concept of social ties, community of interests and the common good. In the proposed understanding, identification is also the result of the concepts of corporeality, routine, tact and discipline analyzed in the text
Comparative analysis of the availability of cinema websites, taking into account the principles of universal design
Authors: Boguta Hanna , Skublewska-Paszkowska Maria
Published: June 2023

The subject of this study is to conduct a comparative analysis of cinema websites, taking into account the principles of universal design. The universal designing is a philosophy which central assumption is to create products, including graphic interfaces so that they are accessible to as many users as possible. An accessibility is a term that describes the extent to which users of different ages, with varying degrees of physical or mental fitness, can use it. Therefore, it is essential to adapt the interface to the largest possible audience when designing the interface. In the paper the following hypothesis has been defined: "The application of universal design principles increases the accessibility of websites”. The "Multikino" website has been selected for the research, which does not require the universal design, and the website created for the purpose of this study that meets these requirements. The research methods used in the study include eye-tracking, checking compliance with WCAG (ang. Web Content Accessibility Guidelines) guidelines using the WAVE (ang. Web Accessibility Evaluation Tool) tool, and conducting an interface assessment survey.
Comparative analysis of frameworks and automation tools in terms of functionality and performance on the Salesforce CRM Platform
Authors: Ciechan Damian
Published: June 2023

Article describes comparative analysis of both code and low-code automation tools together with frameworks used for developing graphical user interfaces that are available on the Salesforce Platform. The research is being carried out due to lack of such comparison in the available literature and due to popularity of the Salesforce CRM. Four automation tools were put together: code-based Apex Triggers and three point-and-click tools: Workflow Rules, Process Builder, Flow Builder. In each of the frameworks (Visualforce, Aura Components, Lightning Web Components) an application module was developed and example logic was implemented in each of the automation tools. DML operations insert, update, delete were compared in terms of performance and each technology was analyzed in terms of provided functionalities and limitations. It was concluded that the most efficient automation tool is Flow Builder and the Lightning Web Components framework is the best choice for developing graphical user interfaces.
Field emission from sharp protrusions of graphite fabricated by sandblasting process
Authors: Yoshimoto Tomomi , Ebina Taiga , Iwata Tatsuo
Published: June 2023

The sandblasting process, a novel method for fabricating field emitters, has been adapted to be used on graphite substrates. The sandblasted graphite substrate features numerous sharp protrusions on its surface that serve as effective field emitters. The threshold of the electric field was found to be 0.78 V μm−1, and linear Fowler–Nordheim plots were achieved. These results demonstrate the potential of the sandblasting process for fabricating graphite-based emitters.
Guest Editor’s Introductory Note. Modern Japan: From the Meiji Restoration to the Takarazuka Revue
Authors:   West University of Timișoara, Sipos George T.
Published: June 2023

This is the first special issue of the Annals of the West University of Timisoara (Humanities Series) dedicated to Asian studies, and I am excited not only that it is focused on Japan, but honored that I was asked to curate it. It’s been a longer than anticipated journey to see this work to completion, but I am proud of the result. The contributions gathered here reflect the importance and worldwide spread of current scholarship on modern Japan. Italian, Korean, American Romanian, and Romanian researchers who teach and do research at universities in Japan, Romania, South Korea and the United States bring an unique and complex universe of themes and methodologies to their contribution to the field.
The Representation of War in Takarazuka Revue’s Performance Strategy
Authors:   Hiroshima University, Grajdian Maria
Published: June 2023

In this paper, I delve into Takarazuka Revue’s performative representation of war, death and suffering with particular focus on the past ten years (since 2014). Based on extensive fieldwork and in-depth literature research, the four pivotal performances chosen as case-studies serve to highlighting the gradual shift from a worldview which rejects war as barbaric towards a vision of/for the future in which war is not only accepted but integrated into the quotidian realities as an inseparable phenomenon. Instead of fighting against war, it seems that the alternative solution proposed by Takarazuka Revue’s recent on-stage developments is to acknowledge war as a means to an end, to achieve and maintain peace as foundation for political stability and economic prosperity.
Precios de la vivienda y la distribución de la riqueza en tiempos de la Gran Recesión
Authors:   , Cóndor Richard , Oviedo Moguel Rodolfo
Published: June 2023

Este artículo utiliza un modelo calibrado a la economía de EUA para analizar el auge y caída de los precios de la vivienda, así como los cambios en la distribución de la riqueza durante los años alrededor de la Gran Recesión. Se replica la dinámica del mercado inmobiliario utilizando choques al ingreso agregado, la distribución del ingreso, las condiciones crediticias y las expectativas de demanda de vivienda futura impulsadas por exuberancia irracional. Encontramos que la exuberancia irracional explica la mayor parte de la dinámica de los precios de la vivienda y que la relajación y posterior endurecimiento de las condiciones crediticias son cruciales para explicar el comportamiento de la deuda hipotecaria, las tasas de incumplimiento y la tenencia de viviendas por parte de los hogares en la parte inferior de la distribución de la riqueza. El auge en los precios de la vivienda condujo a una disminución temporal en la concentración de la riqueza, que se revirtió durante la caída.