bluuebunny/crossref_metadata_2025 huggingface dataset:
Research in TESOL: An Investigation of Trends and Types of Research over the Last Ten Years
Authors: Albiladi Waheeb
Published: December 2019

This paper provides a systematic review of the research around teaching English as a second or foreign language over the last ten years. The review aims to help second and foreign language researchers to recognize the trends that have impacted English teaching and learning research. More than 400 articles from four leading journals (TESOL Journal, TESOL Quarterly, ELT Journal, and Second Language Research) were reviewed to examine the trends and method that were used. The findings suggested that the research interests in the TESOL field have changed as many topics and trends have risen based on students’ academic and social needs. Topics such as teaching methodology, digital literacy, and using technology to teach English have dominated the research during the last decade.
Effectiveness of Brand Management Key Elements in Forming Consumer Loyalty
Authors: Sugiarto Catur , Suryanadi Pram
Published: December 2019

The competitive strength of companies in the current era of global trade is largely determined by the company's ability to manage their brands. The implementation of an effective brand management strategy was proven to have an impact on the formation of competitive advantage through a form of commitment and customer loyalty to the company's brand. This study aims to examine the role of key elements of brand management in shaping customer loyalty. The quantitative study was conducted in order to investigate the effect of brand innovativeness, brand customer orientation, brand self-relevance, and brand social responsibility on brand commitment. 252 responses from Indonesian respondents were collected and then analyzed with Structural Equation Modeling (SEM). The results prove that the four key elements of brand management have a great influence on the formation of brand commitment and loyalty.
The Effect of Organizational Culture, Transformational Leadership and Organizational Environment to the Organizational Commitment and Performance of Private Higher Performance in East Kalimantan Province
Authors: Sugiono Sugiono , Brahmasari Ida Ayu , Ardiana I Dewa Ketut Raka
Published: December 2019

This study aims to analyze the influence of organizational culture, transformational leadership and organizational environment on organizational commitment and performance. 200 responses were collected through surveys gathered from 8 Universities, 34 High School and 15 Academy. Data were analyzed using Structural Equation Model (SEM) and found that the organizational culture, transformational leadership, and organizational environment has a significant effect on organizational commitment and performance of Private Higher Education in East Kalimantan Province except organizational environment has no significant effect on the performance of Private University in East Kalimantan Province. Organizational commitment variable can be a variable that can improve the effect of organizational culture, transformational leadership and organizational environment on the performance of Private Universities in East Kalimantan Province.
The Influence of Nano-Encapsulation of Melastoma malabathricum L. Fruit Extract to Lipid Profile of Broiler Chicken
Authors: Dani Muhammad , Rusman Rusman , Zuprizal Zuprizal
Published: December 2019

The aim of this research was to examine the impact of nano encapsulation of Melastoma malabathricum L. fruit extract as feed additive that was given through drinking water towards lipid profile of broiler chicken. Experimental design used in this research was completely randomized design using six increment treatments of Melastoma malabathricum L. fruit extract to the drinking water of the chicken each with five repetitions. Detail of treatment rations were as follow: T0 drinking water treatment without feed additive (negative control), T1 drinking water treatment + 0.2 mg/kg body weight simvastatin (positive control), T2 drinking water treatment + 1.5% Melastoma malabathricum L. fruit extract, T3 drinking water treatment + 3.0% Melastoma malabathricum L. fruit extract, T4 drinking water treatment + 1.5% nano encapsulation of Melastoma malabathricum L. fruit extract, T5 drinking water treatment + 3.0% nano encapsulation of Melastoma malabathricum L. fruit extract. Observed Parameters were the blood lipid profile, cholesterol of meat and crude fat of meat. The results showed that adding the nano encapsulation of Melastoma malabathricum L. fruit extract did not give significant effect (P>0.05) on blood lipid profile and crude fat of the thigh and breast of the broilers. Addition of nano encapsulation of Melastoma malabathricum L. fruit extract gives real impact (P<0.05) toward reduction of broiler’s meat cholesterol. The conclusion of this research is that giving nano encapsulation of Melastoma malabathricum L. fruit extract is able to improve lipid profile of broiler, which is in the amount of meat’s cholesterol.
Effect of Different Beehives Size and Daily Activity of Stingless Bee Tetragonula Laeviceps on Bee-Pollen Production
Authors: Agus Ali , Agussalim Agussalim , Umami Nafiatul , Budisatria I Gede Suparta
Published: December 2019

Bee activities and colony may affect the production of bee products. Bee-pollen is one of the important products of honeybees, besides of honey. Tetragonula laeviceps is a group member of stingless bees found in tropical region. In Indonesia, Tetragonula laeviceps mostly create a nest in bamboos that make unfortunately difficult for harvesting of its products. The aim of this study was to investigate the effect of different beehives size and the daily activity (morning vs. afternoon) of stingless bee Tetragonula laeviceps on bee-pollen production. This study was conducted in Ngrandu, Katongan Village, Sub-district of Nglipar, Gunungkidul, Yogyakarta. Forty colonies of Tetragonula laeviceps were obtained from bamboos (similar in diameter and length) were transferred into four different group of beehives size (BS) made from dried wood, respectively: 35x17.5x13.5 (BS1); 35x20x17.5 (BS2); 37.5x20x20 (BS3) and 40x20x20 cm (BS4). Each group of beehives size had ten colonies/beehives as replicates. The colonies consisted of a queen bee, eggs, worker bees, and drones were transferred into wood beehives, and they were kept for two months for the study. The bee-pollen was harvested from beehives, separated from the propolis then weighed. The production of bee-pollen in the four different beehives size (BS1: 2.34±2.48 g/colony; BS2: 4.56±3.94 g/colony; BS3: 1.30±1.22 g/colony, BS4: 1.02±0.63 g/colony) was not different (ns) among the groups. The daily activity of bee bring the pollen to the nest in the morning (07.00 to 11.00) was significantly different (P<0.05) among the groups, but not significant (ns) different in the afternoon (14.00 to 17.00). The frequency of bringing in pollen into the hives at the morning is higher than at the afternoon (21.75 vs. 12.43 times/5 minutes). It could be concluded that the colony in beehive size of BS2 (35x20x17.5 cm) has higher daily activities and thus higher bee-pollen production, compared to the other beehives groups.
Pinokio u hrvatskim prijevodima
Authors: Andraka Marija
Published: December 2019

U radu se istražuju hrvatski prijevodi Pinokija od prvoga prijevoda 1943. do današnjih dana. Prvi prijevod uspoređuje se s njegovim kasnijim izdanjima te s ponovljenim prijevodima nastalima 1990-ih i kasnije. Izraz „ponovljeni prijevod“ odnosi se na novi prijevod u istom jeziku već ranije prevedenoga djela (Koskinen i Paloposki 2010). U ovom se radu ponovljeni prijevodi istražuju i u okviru teorijskih postavaka koje razumiju prijevod kao adaptaciju (Klingberg 1986). Dva su glavna cilja istraživanja: (1) utvrđuje se postoje li razlike između prvoga prijevoda iz 1943., njegovih ponovljenih izdanja nakon 1945. i triju ponovljenih prijevoda nastala tijekom 1990-ih i kasnije, s obzirom na različit sociopolitički kontekst u kojem su se pojavili i na utjecaj ideologije na prijevode (v. Pokorn 2012, Hameršak i Zima 2015); (2) na temelju usporedbe prijevoda kulturno specifičnih jedinica, kao što su osobna imena, nazivi za hranu, regionalni i dijalektalni izrazi, tuđice, arhaizmi i frazemi, uspoređuju se prevoditeljske strategije u različitim vremenskim razdobljima i društveno-kulturnim kontekstima te se primjenom hipoteze ponovljenoga prijevoda uz pomoć primjera odomaćivanja i otuđivanja kulturnih sadržaja razmatraju motivi za ponovno prevođenje.
Efficiency of the Use of Humidified Gas Fuel and Oxidizing Mixture
Authors: Soroka B. S. , Vorobyov N. V.
Published: December 2019

The influence of hydration of the components of combustion (air-oxidizer and – in some cases – fuel) including hydration in the conditions of substitution of natural gas by alternative gas fuels, viz. by coke blast furnace mixture and natural blast furnace mixture – on energy efficiency of the use of different fuels has been determined. Calculations of fuel saving for substitution of natural gas (NG) by wet process gas (blast furnace gas (BFG), coke gas (CG), their mixtures) were performed taking into account real technological parameters (on the example of a specific metallurgical plant). All the calculations were performed within the framework of the author’s methodology on fuel substitution grounded on the 1st and the 2nd laws of thermodynamics. The analysis of possibility for saving or overspending NG is performed in the conditions of preservation of the flow of the used total enthalpy (as the main requirement of the methodology that had been proposed) and of taking into account the corresponding efficiency of fuel use. The calculation of the required heat flow of natural gas combustion depending on the content of wet blast furnace gas in NG + BFG mixtures for the cases of NG substitution by process gases has been carried out. It is established that the presence of moisture in the fuel-oxidation mixture always reduces the efficiency of the combustion chamber or the energy process and the unit. In order to increase the efficiency of a high-temperature furnace (boiler), it is necessary to provide heating of combustion components when utilizing the heat of the outgoing combustion products. It is shown that the efficiency of the fuel-using system can be significantly increased when the potential (excess total enthalpy) of the working fluid (combustion products) is activated. There are additiоnal benefits due to the fact that the existing heat of products of combustion with humid air in a full range of temperatures – from the theoretical combustion temperature to ambient temperature under conditions of equilibrium, including account of the heat of condensation – increases with increasing moisture content of the initial components of combustion, viz. air-oxidizer and/or fuel gas.
Thermal Measurement and its Application for Diagnostics of Distribution Oil Transformers
Authors: Korenciak D. , Sebok M. , Gutten M.
Published: December 2019

In the first part of the paper the theory of infrared radiation and the use of nondestructive measurement of electrical devices by means of thermovision are under analysis. In the second part of paper basic principles and application of non-contact temperature measurement are examined. In the third part of paper thermal processes in distribution oil transformer – temperature in dependence on height of oil transformer and temperature distribution in sectional plan of oil transformer – are considered. In the fourth part of paper, by means of the experimental measurements and subsequent analysis, practical thermal imaging and contact thermal measurements by optical detectors for the diagnosis of distribution oil transformers in the field of mechanical strength of windings are shown. In this paper, we wanted to show out the possibility of using thermal measurements in this field of analysis and detection of quality of winding for distribution oil transformer. It is possible to use these methods to localize places of faults, and they are also applicable for the diagnosis and detection of disorders of the quality of materials and other anomalies during operation of the equipment. By means of the experimental measurements followed by diagnostic analysis the practical use of thermovision and optical sensors for diagnostics of power oil transformers in field mechanical strength and quality of winding is demonstrated.
Synthesis of Functionalized Silica from Rice Husks Containing C-I End Group
Authors: Et al. Sobh
Published: December 2019

In this paper, we have extracted Silica from rice husk ash (RHA) by sodium hydroxide to produce sodium silicate. 3-(chloropropyl)triethoxysilane (CPTES) functionalized with sodium silicate via a sol-gel method in one pot synthesis to prepare RHACCl. Chloro group in compound RHACCl replacement in iodo group to prepere RHACI. The FT-IR clearly showed absorption band of C-I at 580 cm-1. Functionalized silica RHACI has high surface area (410 m2/g) and average pore diameter (3.8 nm) within mesoporous range. X-ray diffraction pattern showed that functionalized silica RHACI has amorphous phase .Thermogravemitric analysis (TGA) showed two decomposition stages and SEM morphology of RHACI showed that the particles have irregular shape. Atomic force microscope (AFM) technique was proved that the RHACI  has a nanostructure The XPS spectra of I 3d for all the studied surfaces are presented in the peak located at 618.5 eV binding energy was associated with C–I bond.
Lifestyle factors and reversion to normoglycaemia by prediabetes type in PREDAPS study.
Authors: SORIANO LUCIA CEA , Giráldez-García Carolina , Albadalejo Romana , Franch-Nadal Josep , Mata-Cases Manel , Díez-Espino Javier , Artola Sara , Serrano Rosario , Regidor Enrique
Published: December 2019

Background There is little evidence on how healthy lifestyle factors can explain the variation in the proportion of patients reverting to normal glucose regulation according to type of prediabetesAims To study the role of lifestyle factors on the reversion to normal glucose regulation according to type of prediabetes.Design and Setting Observational prospective cohort study. The Cohort study in Primary Health Care on the Evolution of Patients with Prediabetes from2012-2015Methods Participants were classified, according to the definition established by ADA using either fasting plasma glucose (FPG) levels between 100-125 mg/dL or HbA1c between 39-47 mmol/mol (5.7%–6.4%), in three groups. Reversion to normal glucose regulation was calculated at third year of follow-up. Relationship of lifestyle factor and type of prediabetes with reversion was estimated by means of Odds Ratios (OR) using three sequential models.Results Proportion of reversion rates were 31% for FPG group, 31% for HbA1c group and 7.9% for both altered parameters group, respectively. BMI<25 kg/m2[OR (95% CI): 1.90 (1.20-3.01)], high adherence to Mediterranean diet 1.78 (1.21-2.63) and absence of abdominal obesity 1.70 (1.19-2.43) were the strongest lifestyle predictors for reversion. Compared with those with both altered parameters, OR of reversion of prediabetes was 4.87 (3.10-7.65) for FPG group and 3.72 (2.39-5.78) for HbA1c group. These estimates remained almost the same after further adjustment for biochemical parameters and lifestyle factors.Conclusions Although optimal lifestyle factors showed to be a positive predictor, those do not seem to explain the differences according to the type of prediabetes.
Intracavitary and Extracavitary Iliac Extended Fixation Using Porous Metal Augments for Paprosky Type 3 Acetabular Defects in Revision Total Hip Arthroplasty: A Minimum 2 Years Follow-up
Authors: Tang Hao , Zhou Yixin , Ma Zhuyi , Huang Yong , Guo Shengjie
Published: December 2019

Background: We proposed a new concept of “iliac extended fixation” in revision total hip arthroplasty (THA) as fixation extending superiorly 2 cm beyond the original acetabular rim with porous metal augments, which was further classified into intracavitary and extracavitary fixation. This study reports the minimum 2 years outcome of the iliac extended fixation technique in patients with Paprosky type 3 acetabular defects. Methods: Thirty two revision THA patients were retrospectively reviewed who underwent reconstruction with the concept of iliac extended fixation from 2014 to 2016 in our hospital. Patients were assessed using the Harris Hip Score (HHS) and the Western Ontario and McMaster Universities Osteoarthritis Index score (WOMAC). In addition, radiographs were assessed and patient reported satisfaction was collected. Results: At an average follow-up of 40 months (range 25 – 64 months), the postoperative HHS and WOMAC scores were significantly improved at the last follow-up (p < 0.001). The postoperative horizontal and vertical locations of the COR were significantly improved from the preoperative measurements (p < 0.05). Two (6.3 %) patients were dissatisfied with the outcome. The extracavitary iliac extended fixation group had significantly more horizontal screws fixation (4.6 ± 25.7° vs 41.9 ± 37.8°, p < 0.001) and higher rate of osteointegration in zone 1A (91.7% vs 50.0%, p = 0.023) than the intracavitary iliac extended fixation group. Conclusions: Intracavitary and extracavitary iliac extended fixation with porous metal augments and cementless cups are effective in reconstructing severe superior acetabular bone defects, with promising short-term clinical and radiographic outcome.
Analysis of the potential correlation between gastric cancer and gastrointestinal microbiota via in-silico data mining
Authors: Ding Xuelu , Zhu Yukun , She Zhaoyuan , Liu Xuewen , Zhang Cancan , Ma Xuying , Wang Feng , Wang Fei , Geng Xin
Published: December 2019

Background: Emerging evidence shows the gastrointestinal microbiome might play an important role in the carcinogenesis of gastric cancer. While Helicobactor pylori has been reported to be a specific risk factor of gastric cancer, it is still controversial whether significant difference of non- H. pylori microbiota exists between gastric cancer patients and healthy control.Results: In this study, we employed multiple bioinformatic databases to excavate the potential correlation between gastrointestinal microbiome and gastric cancer. The databases involved in this investigation include HMDB, STITCH, OMIM, GWAS Catalog, WebGestalt, Toppgene, GeneMANIA. In addition, the network diagrams were built by use of Cytoscape software. Notably, our results showed that 33 common genes participate in both gastrointestinal microbiome and gastric cancer. The further analysis of these common genes suggested that there was a wide array of interactions and pathways in which the correlation between gastrointestinal microbiome and gastric cancer is involved.Conclusions: Our present study gives a bioinformatic insight into possible pathways in which the gastrointestinal microbiome play roles in gastric cancer. Future efforts are necessary to be paid to elicit the exact mechanisms as well as potential therapeutic targets of gastric cancer.
Myofibroblasts in Oral submucous fibrosis, Oral squamous cell carcinoma and Normal mucosa- an Immunohistochemical Analysis
Authors: Annamalai Sivachandran , Shamsudeen Shaik Mohamed , thavarajah Rooban , jousha Elizabeth , Rao Uma devi k , Kannan Ranganathan
Published: December 2019

Background: Myofibroblasts are spindle shaped smooth muscle like fibroblast involved in the physiological repair of tissue structure can also cause pathological remodeling of tissue by forming fibrosis. They express smooth muscle actin which can be evaluated for their biological behavior in the physiological and pathological conditions. Aim: To evaluate the expression of Myofibroblasts in oral submucous fibrosis, oral squamous cell carcinoma and normal mucosa by Immunohistochemical analysis. Methods: It is a cross-sectional study done to evaluate the expression of Myofibroblasts in oral submucous fibrosis (Group-1), oral squamous cell carcinoma (Group-2) and normal buccal mucosa (Group-3) using immunohistochemistry using alpha smooth muscle actin in formalin fixed, paraffin embedded tissue specimens. The localization of stain, nature of stain, intensity of stain and the percentage of cells stained among the three groups were studied and compared. Results: The gender distributions in the study were in favor of males. It was observed that Staining Intensity was seen more in group I (30%) than in group II (20%) and progressively increased from early (16.5%) to advance stage(50%) of oral submucous fibrosis. Higher staining intensity was observed in well differentiated oral squamous cell carcinoma. Conclusion: Myofibroblasts are important in normal healing process, but can induce fibrosis. In oral submucous fibrosis, they can be used to assess the severity of the lesion by their increased expression of alpha smooth muscle actin. In oral carcinogenesis increase in the number of alpha smooth muscle actin can change the distribution pattern results in tumor invasive characteristics. Key Words: Myofibroblasts, Alpha smooth muscle actin, Staining intensity, Oral Submucous Fibrosis, Oral Squamous Cell Carcinoma.
Aberrant expression of PD-1 on B cells and their subpopulations in systemic lupus erythematosus and association with clinical parameters
Authors: changhao xie , Lu Yang , Zhu Qingqing , Li Yun , Wang Qiyi , Jiang Chao , Li Zhijun , Wang Hongtao , Wang Yan , Zhang Wei , Wang Yuanyuan
Published: December 2019

Background: The binding of programmed death 1 (PD-1) with its ligands inhibits the T cell activation and proliferation. But role of the PD-1 pathway on B cells is unclear. In present study, we aimed to evaluate the expression of PD-1 on B cells and their subpopulations and association with clinical parameters in systemic lupus erythematosus (SLE).Results: The frequency of B cells increased significantly in patients with active SLE compared with healthy controls and patients with inactive SLE.The proportions of CD19+ IgD- CD27- cells andplasmablast cell among total B cells were significantly higher in patients with SLE compared with controls. The percentage of PD-1+ B cells was higher in patients with in active SLE than in healthy controls. The proportion of PD-1+ B cells was correlated with lupus nephritis, complement components, IgG, SLE Disease Activity Index, and autoantibodies. PD-1+ B cells from SLE showed a high proliferative response. The levels of IgG and anti-dsDNA secreted by PD-1+ B cells from SLE patients was higher after 7 days compared with that by PD-1- B cells from patients with SLE and healthy controls.Conclusions: The expression of PD-1 on B cells and their subpopulations was aberrant and was associated with clinical parameters in SLE.KEY WORDS:PD-1; B cells; subpopulation; systemic lupus erythematosus
Expression and Significance of protein 4.1R in rat models with diaphragmatic weakness
Authors: Li Yanhong , Li Yongqiang , Ji Xinying , Li Huimin , Wu Dongdong , Wei Wenqiang , Wang Xinchun
Published: December 2019

Abstract Background To explore the significance of protein 4.1R expression in the diaphragmatic weakness animal and cell models and its preliminary mechanism.Methods Rats were intraperitoneally injected with Lipopolysaccharide (LPS) to construct diaphragmatic weakness models. Histopathology of diaphragmatic tissues was detected by Hematoxylin eosin(HE) staining. L6 cells were induced by LPS to establish the myasthenic cell models and transfected with 4.1R-siRNA to konckdown 4.1R. Immunohistochemistry was performed to detect the expression of acetylcholine receptor(AchR) and 4.1R; The expression of desmin and myosin in tissues and cells were detected by western blot.Results LPS could induce the diaphragmatic weakness of rats. The expression of AchR in diaphragmatic weakness tissues was lower, while that of desmin was higher than that in the control group. 4.1R was up-regulated in the diaphragmatic weakness models, and related to the severity. After knockdown of 4.1R in LPS induced L6 cells, the expression of AchR was up-regulated significantly. But there was not difference of contractile proteins.Conclusions Protein 4.1R was upregulated in diaphragmatic weakness model in vivo and in vitro and might be involved into the occurrence of myasthenia gravis by negatively regulating the expression of AchR.
Dental Health and Dental Care Utilization Among Able-Bodied Adults on Medicaid in Kentucky After Medicaid Expansion: A Mixed Methods Study
Authors: Wang Tim T , Dixon Erica L. , Bair Elizabeth F , Ferrell William , Linn Kristin A. , Volpp Kevin G. , Underhill Kristen , Venkataramani Atheendar S.
Published: December 2019

Background. Dental utilization remains low among adults on Medicaid, despite the ACA expansion increasing access to care in many states. It remains unclear whether low utilization reflects low demand or other barriers. Our objective was to examine factors associated with poor perceived dental health and low dental utilization among adults on Medicaid. Methods. We conducted a large survey of able-bodied adults (N=9,363) on Medicaid in Kentucky from between May and September 2018, which included questions on perceived dental health and utilization of dental care. Semi-structured interviews were also conducted with a subset of participants (N=127) from May to November 2018. Results. 37.8% of respondents reported fair or poor oral health, higher than the 26.2% with fair or poor physical health. 47.6% indicated needing dental care in the last six months, but only half of this group reported receiving all the care they needed. Both low demand and a number of barriers, including lack of coverage for needed services and lack of access to care (low provider availability, transportation difficulties), appeared to explain low rates of utilization. Conclusions. Low dental utilization reflects a combination of low demand and barriers to care. Coverage and access issues could be mitigated by expanding the range of covered services and increasing provider availability.
Factors affecting community based health insurance utilization in Ethiopia: A systematic review
Authors: Bayked Ewunetie Mekashaw , Kahissay Mesfin Haile , Workneh Birhanu Demeke
Published: December 2019

Background: The goal of health care financing in Ethiopia has been to achieve universal health care coverage by minimizing the catastrophic out of pocket health service expenditure. Even though the performance was not as planned, the promising strategy to achieve universal health care coverage in the informal sector was community based health insurance which was expected to cover more than 83 % of the population. So, we systematically reviewed determinants of community based health insurance utilization in Ethiopia. Methods: We searched DOAJ, EconBiz, ERIC, Google Scholar, Oxford Journals, PubMed, SpringerLink, Europe PMC, Microsoft Academic Search, OAIster and AJ including various relevant websites by March 9 to 10, 2019. We included articles regardless of their publication status with both quantitative and qualitative approaches. Results: The factors determining community based health insurance utilization in Ethiopia were found to be associated with supply side, health facility, demographic and socioeconomic predictors. Among demographic and socio-economic factors, the report of the studies regarding to gender and age was not consistent. However income, education, community participation, marriage, occupation and family size were found to be significant predictors and were positively related with the scheme’s utilization. With respect to health status and health service related factors; illness experience, benefit package, awareness level, previous out of pocket expenditure for health care service and health service status (quality, adequacy, efficiency and coverage) were significantly and positively related but premium amount, self-rated health status and bureaucratic complexity were found to be negative predictors. Conclusion: To achieve universal health care coverage through community based health insurance, it is advisable that special attention should be given to income level, education, community participation, marriage, family size, benefit package, awareness level and health service quality, premium amount and bureaucratic or governance issue.
Complete sequence of two potentially epidemic KPC-harbouring plasmids in Klebsiella pneumoniae ST11 strains in China
Authors: Zhai Yao , Li Daixi , Du Pengcheng , Zhang Zhao , He Zilong , Guo Yatao , Chen Yusheng , Kang Yu , Hu Songnian , Gao Zhancheng
Published: December 2019

Background: Klebsiella pneumoniae carbapenemase (KPC) has spread across the world. The present study focuses on explore sequence and evolution pathway of two potentially epidemic KPC-harbouring plasmids in Klebsiella pneumonia isolated from Southern China.Methods: Eighteen carbapenemases-producing Klebsiella pneumonia isolates were collected in a tertiary teaching hospital in 2014 in Southern China. The KPC production, antimicrobial susceptibility and MLST were tested for all isolates. Plasmids were purified for all isolates. Plasmids of six isolates were randomly selected to perform Single-molecule real-time sequencing, annotation and bioinformatics analysis. Conjugation and transformation experiment were also performed for the six selected plasmid samples. Furthermore, PCR screening based on the plasmid sequences information were performed for other twelve isolates, to identify the prevalence of the identified plasmids.Results: Two new KPC plasmids, pF5 and pF77, were identified and detected to be highly epidemic in the collected isolates with the rate of 77.8% (14/18), and 92.9% of the plasmid-harbouring isolates were identified in sequence type (ST) 11 group. pF5 belongs to the incompatibility group IncR and IncFIIk, and pF77 belongs to IncFIIk. The two plasmids were non-conjugative. By sequencing and comparing the plasmids sequences in detail, we found these plasmids carrying bla KPC-2 , bla CTX-M-65 , bla SHV-12 , catA2 and fosA3 antimicrobial genes. Additionally, the two plasmids both showed a close relationship with the other two reported KPC-harbouring plasmids pKP1034 and pCT-KPC, which have highly similar backbones and have been considered to evolve from some recombination events of other closely related plasmids pHN7A8, pKPC-LK30 and pKPHS2. We noticed that these previous reported plasmids and our plasmids all have been detected in the period of 2013-2014 in Southern China, share similar backbone and carried by the clonal ST11 K. pneumonia strains.Conclusions: The plasmids were identified and detected to be highly epidemic in the collected isolates. A potential evolutionary pathway from pHN7A8-, pKPC-LK30 and pKPHS2-derived plasmids in Klebsiella pneumoniae strains in China was hypothesised.
Genomic insights and probiotic characteristics of Bifidobacterium gallinarum CACC 514 isolated from canine
Authors: Jung Min Young , Kim Yangseon , Kim Jung-Ae , Kim Dae-Hyuk
Published: December 2019

Background: The genus Bifidobacterium includes common healthy gut microbes in mammals and is widely acknowledged as a probiotics with health-promoting properties. Results: Bifidobacterium gallinarum CACC 514 was isolated from canine feces and its potential probiotic properties were characterized by comparative and functional genome analyses.The complete genome of strain CACC 514 was found to be 2.4 Mb, with a G + C content of 63.9 mol%. The strain possessed factors beneficial to mammalian health based on the presence of genes related to mucosal surface adhesion proteins, stress-related genes, and extracellular polysaccharide genes. A comparative genome analysis with other Bifidobacterium species revealed the unique characteristics of this species. These functional genomics have been confirmed for its superiority by probiotic properties, acid and bile tolerance, and adhesion to mucus. Conclusions: The genome analysis and in vitro probiotics characteristics revealed its superiority in the intestine. These results add to our comprehensive understanding of B. gallinarum and suggest that this strain has potential application in mammalian probiotics. Keywords: Bifidobacterium gallinarum, gut microbe, probiotics, genome analysis, canine, feces.
Intercultural Learning: A Promising Pedagogy in the New Millennium
Authors: Echcharfy Mouhssine
Published: December 2019

In a multicultural context, most of the common problem among individuals is that people hold an ethnocentric perspective, as they tend to idealize their own culture and ignore cultural difference. In this regard, interculturalism has come into play as it encourages ethno-relative perspective in that it stresses the importance of openness to and acceptance of different beliefs, values and customs (e.g., Coulby, 2006; Lentin & Titley, 2011; O’Cinneide, 2012; Jokikokko & Karikoski, 2016).This intercultural trend has led to the emergence of a new language pedagogy called “Intercultural Learning” that aims at promoting intercultural competence in EFL classrooms and prepare EFL learners to meet the challenges of such a globalized world. The thrust of the argument in this paper is that culture courses should not be a place where learners are exposed only to the target culture; it should rather be a place where learners can experience cross-cultural situations, reflect on their experience, and act as intercultural speakers/mediators with the ability to communicate and interact appropriately and effectively in different intercultural situations. It offers insights into the challenges that lead to the emergence of intercultural learning. It also gives an account of the importance of culture in language learning. The paper discusses intercultural learning pedagogy, as it defines the notion of intercultural learning, discusses its principles and explains the key element of intercultural learning “experiential learning” and how it is implemented. It also provides implications for teachers at the university level.
Heiner Goebbels's Stifters Dinge and the Arendtian Public Sphere
Authors: Matthews Luke
Published: December 2019

Heiner Goebbels’s works are examples of “postdramatic” theatre works that engage with the political by seeking to challenge socially ingrained habits of perception rather than by presenting traditional, literary-based theatre of political didacticism or agitation. Goebbels claims to work toward a “non-hierarchical” theatre in the contexts of his arrangement of the various theatrical elements, in fostering collaborative working processes between the artists involved, and in the creation of audience-artist relationships. In offering a reading of Goebbels’s “no-man show” Stifters Dinge, this paper seeks to situate Goebbels’s practice within a theoretical tradition that also encompasses Hannah Arendt’s deployment of the theatre as a metaphor for the public sphere. Within this analysis, I suggest, theatre can be seen to offer the possibility of a participatory democracy through its attention to disappearance and absence.
Spatial Assessment of Commuting Patterns in India's National Capital Region
Authors: Jain Manisha , Hecht Robert
Published: December 2019

Contemporary urbanization as experienced in India is characterized by urban sprawl, which increases commuting distances and promotes private individual transport. This article takes India's largest region as a case study and uses data from the Census of India on commuting, the population,
socio-economic and infrastructural factors as well as spatial data on urban and rural administrative boundaries to understand commuting patterns. This article has two major objectives: first, to map spatially commuting patterns (distances to work and modes of travel); second, to estimate the
effect of people-based (minorities, illiteracy rate, household facilities) variables and place-based (basic amenities, road and rail network densities, etc.) variables on commuting. The research findings are as follows: short trips are prevalent in urban areas, while intermediate and long
trips are prevalent in rural areas. Short trips are common in areas with a high share of minorities as well as illiteracy rates. Long trips are undertaken by public transport such as trains and buses, intermediate trips by two-wheelers and buses, and short trips on foot and by bicycle. Areas
with high prevalence of long trips have a better provision of basic amenities. The paper recommends the following measures to reduce motorization and long commuting distances: (i) government initiatives to reduce private transport and promote transitbased transportation; (ii) the integration
of rural and urban areas through public transport; (iii) the establishment of a unified regional transportation authority to integrate regional transportation; and (iv) the introduction of subsidies to reduce private transportation and the implementation of transportation policy proposals.
Los monolitos del cañón del Colca, Choqquetico, distrito Maca, Arequipa, Perú
Authors: Deza Rivasplata Jaime , Molina Leoncio
Published: December 2019

El presente es un estudio etnoarqueológico que comprende la exploración de superficie, reconocimiento y descubrimiento para la ciencia, de diez monolitos que representan terrazas de cultivo con sus canales de distribución, ubicados en la orilla o margen izquierdo de los inicios del cañón y una piedra de superficie plana, de forma rectangular, de quince metros cuadrados y de altura con dirección NO y 27 hoyos cónicos, aprovechando la suave inclinación (5 grados) que mira al nevado apu Bombaya, como queriendo reproducir el paisaje que observa frente a él. En la otra banda del río, que es la zona donde se han construido cientos de andenes y se desarrollan las actividades agrícolas del Colca, se observan lagunas de almacenamiento que reciben el agua que procede del deshielo de los nevados de la Cordillera Chila. Lagunas que proveen de agua permanente para el cultivo y para la vida de las comunidades.
STORYTELLING SONGS OF THE ÈWÈ-DÒMÈ OF GHANA
Authors: Gbagbo Divine Kwasi , Elder D. Rose
Published: December 2019

For the Central Èwè or Èwè-Dòmè people of Ghana’s Volta Region, storytelling is a vital practice used to transmit key lessons. For centuries the Èwè- Dòmè employed storytelling performances in initiation rites, war celebrations, wake-keeping, and praise singing to enrich the gathering by relaying important information, building group identity, and binding the community together with story, song, and dance. Storytellers and community participants point to the role that songs play within storytelling as cultural markers for the Èwè-Dòmè communities in the area around Ho, the Volta Region’s capital. Within the framework of extended family or town-wide storytelling performances, audience members habitually interrupt the story with song and dance that enlivens sleepy listeners and augments the story with an interpretive angle on the theme. Singing reverses the artist-audience roles. Other community events similarly provide an opportunity for artist-audience interaction and the reversal of roles. This paper documents the social role of songs in the context of storytelling as well as the performance practices, texts, melodies, rhythms, and harmonies of this important traditional musical genre in the face of numerous threats to its ongoing existence.
“SINGING THE HEALING”: THE RITUALS OF THE TWELVE APOSTLES CHURCH IN GHANA
Authors: Asare Amos Darkwe
Published: December 2019

While many in Ghana prefer modern medical systems, others use indigenous means such as those emanating from shrines and indigenous sects. Today, many religious practices in Ghana focus a greater part of their services on healing and the general wellbeing of its members. The formation of African Indigenous Churches (AICs) has played a central role in bridging the gap between indigenous and Christian concepts of worship, healing, and wellbeing. The Twelve Apostles Church, first of the AICs in Ghana, is prominent as far as good health and the wellbeing of its members are concerned. These indigenous musical healing practices are seldom recognised for their significant contribution towards good health and wellbeing. In this article, I use an ethnographic approach, employing interviews and participant observation, to describe the significance of the musical healing rituals of the Twelve Apostles Church in Ghana. The question is, how does drumming, dancing, and singing in the Twelve Apostles Church contribute to good health and wellbeing?
Treatment of paraarticular tissue pathology with perifocal combination injections
Authors: Khitrov N. A.
Published: December 2019

Introduction: the article describes the most common variants of paraarticular tissue pathology (PTP) - enthesitis of the upper and lower extremities, back. The issues of enthesitis etiology, pathogenesis, clinic presentation, diagnosis, differential diagnosis are considered. The historical background, technique and mechanism of action of perifocal syringe injections are presented.

Objective of the study: evaluate the clinical efficacy of perifocal syringe injection of Alflutop in patients with enthesitis of the upper and lower extremities and back.

Materials and methods of the study:76 patients with shoulder joint enthesitis (30 patients), epicondylitis (10), back pain (14), trochanteritis (13), anseritis of the knee joints (9) received treatment with perifocal injections of Alflutop as a course of 5 injections with an interval of 1 injection every 2 -3 days. We evaluated general well-being, local pain at rest, during palpation and movement, range of motion. The diagnosis was established clinically, and using the results of x-ray examination, ultrasound, MRI.

The results of treatment: significant outcomes in patients, which included improved well-being, reduced pain, increased range of motion. 69 of 76 patients demonstrated significant improvement and improvement - the effectiveness of therapy was 90.8% with high tolerability of the drug.
Otizm Spektrum Bozukluğu Olan ve Tipik Gelişim Gösteren Çocukların ve Annelerinin Jest Kullanımlarının Karşılaştırılması
Authors: AKIN  BÜLBÜL İşık , ÖZDEMİR Selda , TÖRET Gökhan
Published: December 2019

Bu araştırmada 11-72 ay aralığındaki otizm spektrum bozukluğu olan (OSB; 6 kız, 24 erkek) ve tipik gelişim
gösteren (TGG; 13 kız, 17 erkek) çocukların ve annelerinin jest kullanım düzeyleri sosyal etkileşim (SE), ortak
dikkat (OD), davranış düzenleme (DD) ve sergilenen tüm jestlerin toplamından elde edilen toplam (TPLM) jest
kategorilerinde incelenmiştir. Araştırmanın bulguları, OSB’li çocukların tüm jest kategorilerinde daha düşük
düzeyde jest sergileyerek TGG’li akranlarından farklılaştıklarını göstermiştir. OSB’li çocuğa sahip annelerin ise
DD, SE ve TPLM jest kategorilerinde daha düşük düzeyde jest sergileyerek TGG’li çocuğa sahip annelerden
anlamlı düzeyde farklılaştıkları belirlenmiştir. OSB’li ve TGG’li çocukların jest kullanım farklılıklarının,
annelerinin jest kullanımlarından kaynaklanıp kaynaklanmadığı incelendiğinde, OSB’li ve TGG’li çocukların jest
kullanımlarındaki puan farklılığının annelerinden bağımsız olduğu bulgulanmıştır. Annelerin jest kullanımındaki
farklılığın, çocukların jest kullanımından kaynaklanıp kaynaklanmadığı incelendiğinde ise araştırma sonuçları,
OSB’li annelerin SE ve TPLM jest kategorine ait puanlarında bulgulanan farklılığın kaynaklarından birinin
çocukların jest kategorilerinden elde ettikleri puan farklılığı olduğunu göstermiştir. Araştırma bulguları tartışılmış
ileri araştırmalara yönelik önerilere yer verilmiştir
Analisis Permasalahan Guru dan Siswa Terkait Pembelajaran Teams Games Tournament (TGT) dan Student Teams Achievement Division (STAD) Terhadap Motivasi Prestasi dan Prestasi Belajar Biologi
Authors: Jamilah Siti , Boleng Didimus Tanah , Labulan P M
Published: December 2019

This needs analysis aims to determine the problems that occur in Biology learning activities at SMAN1 Anggana. Application of learning models that suit students' needs. The research sample in this analysis is a class X student at SMAN 1 Anggana. The results of the observations showed that as many as 50.00% of the students' daily daily test results used the lecture method. This is because several things include students not paying attention to the teacher during the learning process, students playing with their peers, and monotonous learning. The teacher states that students tend not to ask questions in learning. In addition, the problem that is also faced is that there are still many teachers who apparently have not implemented learning models that can make students more active so students tend to be saturated. The way that can be taken to overcome this problem is by applying the team games tournament (TGT) learning model and the student teams achievement division (STAD). From the observations in the form of analysis of the problems of Biology teachers and students of SMAN 1 Anggana, it can be concluded that the ability of teachers to overcome problems in learning needs to be improved so that students are more active and happy to learn biology.
Vocational Teachers Challenges in Developing Their Professional Competence in Indramayu
Authors: Prawiro Indra Yoga
Published: December 2019

As ESP teachers, the teachers are always forced to maintain their knowledge because the development of specific knowledge is changing very fast. The teachers should progressively develop their competence because it will influence the goal of teaching (Latha, 2014). This study focuses on investigating the kinds of challenges that have faced by vocational teachers in developing their professional competence. The research design of this study is a case study. The participants of this study were five vocational teachers who have been teaching in Vocational Schools in Indramayu at least for about two years. The writer used a semi-structured interview to collect the data. The data from the meeting were transcribed and analyzed qualitatively. The result showed that there are three main challenges in developing professional competence. Those challenges are the availability of seminars and workshops in their city, the less support from the institution, and the lack of facilities and infrastructure.
Destino de Prazer: Turismo e prostituição na ótica de travestis em Natal/RN, Brasil
Authors: Gurgel Kauay Vinícios , Silva Michel Jairo Vieira da , Lanzarini Ricardo
Published: December 2019

Desde o final dos anos 1990 a prostituição de travestis na cidade de Natal/RN atende ao mercado turístico, especialmente pelas ruas do bairro de Ponta Negra, mas também por toda a cidade, como uma atividade marcante. Então, esta pesquisa tem por objetivo compreender a dinâmica social entre a prostituição de travestis e o fenômeno turístico na cidade de Natal/RN, a fim de identificar o perfil dessas travestis e dos espaços utilizados por elas, além do perfil de turista que consome esses serviços. A trajetória metodológica contou com uma abordagem qualitativa sobre o depoimento de seis travestis e foi desenvolvida por meio de uma pesquisa exploratória-descritiva entre julho de 2017 e maio de 2018. Após a realização das entrevistas semiestruturadas, foi possível considerar que o perfil das entrevistadas tem semelhanças de faixa etária e de conflitos sociais em virtude da identidade de gênero, fato que as aproxima sob o prisma do preconceito e marginalidade, mas com disparidades em relação à escolaridade e renda, o que as distancia em relação ao consumo de bens e poder aquisitivo, seleção do perfil de público e local que atendem. Já o perfil da clientela turística é, quase sempre, de homens casados e de meia idade provenientes, majoritariamente, do continente europeu.

Palavras-chave: Prostituição. Turismo. Travestis. Natal/RN. Identidade de Gênero.