PREVALENCE OF ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN AND ADOLESCENTS OF DAGESTAN AND THE CONTENT OF Mg, K, Ca, Zn, Pb IN SOILS AND NATURAL WATERS OF THE TERRITORY
Authors:   Precaspian Institute of Biological Resources of the Dagestan Federal Research Centre of the Russian Academy of Sciences, Makhachkala, Republic of Dagestan, Russia, Salikhov Sh.K. , Alieva D.Z. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Magomedova U.A. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Abdulkadyrova S.О. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Surkhaeva Z.Z. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Agaeva E.N. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Tagirova Z.G. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Ataev M.G. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Yahyaev M.А. ,   Precaspian Institute of Biological Resources of the Dagestan Federal Research Centre of the Russian Academy of Sciences, Makhachkala, Republic of Dagestan, Russia,   Scientific and Research Institute for Environmental Medicine named after S.A. Abusuev with the Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia, Adilova M.A. ,   Dagestan State Medical University, Makhachkala, Republic of Dagestan, Russia
Published: September 2021

The aim of the study is to determine the role of geochemical factors (the content of Mg, K, Ca, Zn, Pb in soils and natural waters of the plain zone of Dagestan) in the prevalence of essential arterial hypertension (EAH) among the population of children. Materials and methods of research: an observational cross-sectional (one-step) study of the prevalence of EAH in the child population was carried out. The prevalence rates of EAH among children in the plain zone of the Republic of Dagestan are calculated for 100,000 children 0–17 years old, without taking into account gender differences. The content of elements (Mg, K, Ca, Zn, Pb) in the environment (soil, natural waters) was determined by atomic absorption spectroscopy. Results: one-way analysis of variance (One-Way ANOVA) of indicators of the content of metals (Mg, K, Ca, Zn, Pb) in the regions and objects (soils, natural waters) of the study revealed a statistically significant difference in the data (for soils: F=81,06772, p<0,0002; for natural waters: F=58,86451, p<0,00001). The dependence of children's EAH on the content of chemical elements in the objects of the biosphere of Dagestan was determined, which was expressed in an increase in the number of patients with EAH when Pb content exceeded (r=+ 0,576, r=+ 0,759) and with the decrease of Mg (r=–0,668, r=–0,173), K (r=–0,440, r=–0,636), Ca (r=–0,693, r=–0,533), Zn (r=–0,051, r=–0,827) in soils and natural waters. Conclusion: when assessing the pathogenesis of EAH in the population of children, the content of Mg, K, Ca, Zn, Pb in soil and water should be taken into account, since these microelements, entering the body with water and food, affect the elemental status of child's body.