bluuebunny/crossref_metadata_2025 huggingface dataset:
Peningkatan Hasil Belajar Peserta didik Menggunakan Model Kooperatif Tipe STAD Berbantuan Video Pembelajaran di Kelas III Sekolah Dasar
Authors: Sari Anggun Novita , Desyandri Desyandri
Published: August 2023

Penelitian ini dilatarbelakangi oleh masalah rendahnya hasil belajar peserta didik pada pembelajaran tematik terpadu di kelas III sekolah dasar. Hal itu disebabkan oleh pelaksanaan pembelajaran yang masih berpusat pada guru dan belum menggunakan model serta media pembelajaran yang dapat meningkatkan keaktifan peserta didik. Penelitian ini bertujuan untuk mendeskripsikan peningkatan hasil belajar peserta didik pada pembelajaran tematik terpadu menggunakan model kooperatif tipe STAD berbantuan video pembelajaran di kelas III SDN 28 Rawang, Kabupaten Solok Selatan. Jenis penelitian ini adalah penelitian tindakan kelas dan menggunakan pendekatan kualitatif dan kuantitatif. Dilaksanakan dalam dua siklus dengan prosedur penelitian disetiap siklus meliputi perencanaan, pelaksanaan, pengamatan dan refleksi. Hasil penelitian menunjukkan adanya peningkatan pada: a) RPP pada siklus I pertemuan I memperoleh persentase 93,18%, pada siklus I pertemuan II memperoleh persentase 95,45%, dan pada siklus II memperoleh persentase 97,72%, b) aktivitas guru pada siklus I pertemuan I memperoleh persentase 71,87%, pada siklus I pertemuan I memperoleh persentase 87,5%, dan pada siklus II memperoleh persentase 96,87%, c) aktivitas peserta didik pada siklus I pertemuan I memperoleh persentase 71,87%, pada siklus I pertemuan I memperoleh persentase 87,5%, dan pada siklus II memperoleh persentase 96,87%, dan d) hasil belajar peserta didik pada siklus I pertemuan I memperoleh nilai rata-rata 70,41, pada siklus I pertemuan II memperoleh nilai rata-rata 74,02, pada siklus II memperoleh nilai rata-rata 85,77. Dari hasil penelitian yang dilakukan, dapat disimpulkan bahwa model kooperatif tipe STAD berbantuan video pembelajaran dapat meningkatkan hasil belajar peserta didik.
Psychogenic non-epileptic seizures following COVID-19 vaccine: A report of two cases in Colombia
Authors: Villalobos-Comas Julio Cesar , Castillo-Támara Edgard Eliud , Montaño Lozada Juan Manuel , Cardona Moica Sandra Marcela
Published: August 2023

The novel coronavirus SARS-CoV-2 has caused the death of more than 5 million of people worldwide. Vaccination is the best strategy for controlling the pandemic with an estimated of more that 4 million of people completely vaccinated. The reported adverse events secondary to vaccines against SARS-CoV-2 are mainly mild and moderate, however, there are raising concerns about more severe and long-term outcomes, as well as neurological complications due to the vaccine.
We present two cases of psychogenic non epileptiform seizures (PNES) in Colombian female patients, following vaccination against Covid-19. There is no evidence of similar adverse reactions reported on the literature and thus, we decided to report these events in order to help clinicians in recognizing early and properly all the possible neurological manifestations related to this novel approach, that aimes to eradicate the viruses which has come along with worldwide devastating consequences in terms of health and social issues.
Research on the reform of music education in universities in China based on the cultivation of core elements
Authors: Yang Yi
Published: August 2023

The article first analyzes the significance of the curriculum reform of music education in universities under the guidance of core literacy, analyzes the demands of curriculum reform, and then expounds the problems existing in the current music education curriculum in universities, and puts forward reform measures, aiming at perfecting the music education curriculum in universities and promoting the good growth of students.
Development of economic globalization under the conditions of polycentrism
Authors: Perskaya Victoriya
Published: August 2023

The purpose of this article is to analyze the transformational process of economic globalization itself, which received new impulses in the conditions of its combination with the ideas of building an American-centric world economy, and is transformed during the transition of the world community to a multipolar structure.
Implementing Machine Learning Techniques for Continuous Emotion Prediction from Uniformly Segmented Voice Recordings
Authors: Diemerling Hannes , Stresemann Leonie , Braun Tina , von Oertzen Timo
Published: August 2023

This article presents a novel approach to recognizing emotions from generated 1.5-second audio recordings, utilizing 1510 unique samples sourced from two distinct databases in German and English. Features extracted from these recordings are employed in Deep Neural Networks (DNN), spectrogram features for Convolutional Neural Networks (CNN), and a hybrid model combining both (C-DNN) for emotion prediction. The study underscores challenges in merging datasets due to their heterogeneity, language disparities, and the intricacies of trimming audio recordings. Nevertheless, the results demonstrate that these models achieve an accuracy considerably above random guessing and are on par with human ratings. Given the shortness of the used sample length, this method holds promise for estimating emotional shifts in continuous, longer speech data.
The Usage of Mindsponge Theory for Explaining the Association between Health Status and Subjective Life Expectancy among Older Indian Adults
Authors: SARI NI PUTU WULAN PURNAMA
Published: August 2023

In the area of gerontology, the differences in subjective life expectancy (SLE) between gender and socioeconomic status were unexplored in low-resource settings, especially in countries with rapidly aging populations like India. Kumar et al. [1] aimed to analyze the association between SLE and subjective-objective health status among older Indian adults. By studying 5,969 older adults aged 60 years and above in India, Kumar et al. [1] found that the majority reported a 100% probability of survival for one more year. Older men reported a greater average probability of survival than women, but the ones with poor self-rated health, underweight, and depression had a significantly lower SLE for a 1-year period. On the other hand, older women with poor self-rated health had a significantly lower SLE for a 10-year period, but the one with cognitive impairment had a significantly lower SLE for a 1-year and 5-year period. Study findings may benefit health professionals and public policymakers in planning targeted interventions that can benefit at-risk population cohorts. Kumar et al. [1] utilized the mindsponge theory as the study framework because the mindsponge mechanism can link contextual factors with an individual's health evaluation [2]. Mindsponge theory is a construct that proposes how individuals process information and suggests that contextual factors, e.g., socio-cultural settings, available healthcare services, and health-related information, positively impact the individual's health evaluation [3]. When exposed to new health information, he will apply the multi-filtering process to gauge the new information inputs for benefits and alignment with his core values. When the new information is perceived as beneficial for health, the individual will incorporate it into his mindset, determining his perceived longevity [1]. SLE is a result of positive individual health evaluation, which may provide evidence for identifying and prioritizing policies for vulnerable older populations. Information on several health outcomes which may influence SLE could guide targeted interventions for Indian aging populations.
Agronomic adaptation strategies to climate change may increase soil greenhouse gas emission
Authors: Grados Diego , Kraus David , Haas Edwin , Butterbach-Bahl Klaus , Olesen Jørgen Eivind , Abalos Diego
Published: August 2023

Climate change poses a significant threat to agriculture, highlighting the need for adaptation strategies to reduce its impacts. Agronomic adaptation strategies, such as changes in planting dates, fertilization, and irrigation, might sustain crop yield. However, their impact on soil greenhouse gas (GHG) emission is unknown under future climate scenarios. Using the LandscapeDNDC model, we assessed the effect of agronomic adaptation strategies (early sowing, increased fertilization dose, and increased irrigation amount) on soil GHG emission, yield, and yield-scaled GHG emission. A diversified crop rotation (potato – winter wheat – spring barley – faba bean) of a long-term experiment in Denmark was used for model validation. The adaptation practices to climate change were implemented for two representative concentration pathways (RCPs; 4.5 and 8.5) and five coupled global circulation and regional climate models. The adaptation scenarios were contrasted against a baseline scenario under current management practices. Soil-related variables showed better model fit (refined index of agreement ≥ 0.38) and lower errors (mean absolute error ≤ 8.18) than crop-based outputs for model validation. A total yield of ~29 (± 3) t DW ha-1, and soil GHG emission of ~3.02 (± 1.39) t CO2e ha-1 (RCP8.5) were obtained for the crop rotation system under the baseline for 2071-2100. Early sowing and its combination with increased fertilization decreased the yield compared to the baseline by 6.1 and 4.8%, respectively (RCP8.5). Conversely, early sowing with increased irrigation, and early sowing with increased fertilization and irrigation, produced higher yields by 2.3 and 4.0%, respectively (RCP8.5). All the agronomic adaptation strategies increased soil GHG emissions (ranging from 4.1 to 17.8%) as well as yield-scaled GHG emissions (varying from 3.0 to 12.9%) (RCP8.5). The highest soil GHG emission was simulated for early sowing in combination with increased fertilization and irrigation. Our study indicates that soil GHG emission will increase over the coming decades and that the agronomic adaptation strategies needed to sustain food production may further exacerbate this emission.
“I’m the leader and I’m going to save the world”: Characterizing Empowering and Disempowering Game Experiences
Authors: Vornhagen Jan Benjamin , Bennett Dan , Murphy Dooley , Mekler Elisa D
Published: August 2023

Empowering people through technology is a core concern of HCI, yet little is known about how players experience empowerment or disempowerment through videogames. We surveyed 250 participants about their dis-/empowering videogame experiences, investigating why they felt dis-/empowered, and how these experiences related to core player experience constructs including emotion and basic needs satisfaction. While empowering experiences were often positive, and disempowering experiences often negative, we found meaningful exceptions to this, and a surprising complexity in player accounts. We capture this diversity in seven themes. These range from “heroic victories´´ which follow long periods of failure, to positive experiences of disempowerment, which were appreciated for their narrative meaning. By articulating these complex experiences, and relating them to quantitative measures we provide a foundation for understanding of the role of dis-/empowerment in player experience, and highlight avenues for future work. Data and analyses are available at https://osf.io/zhtu8/
Gender relations and decision-making on climate change adaptation in rural East African households: A qualitative systematic review
Authors: Niemann Johanne , El-Mahdi Miriam , Samuelsen Helle , Tersbøl Britt  Pinkowski
Published: August 2023

Background: Climatic changes are threatening rural livelihoods in East Africa. Evidence suggests that climate change adaptation in this context might reproduce inequitable intra-household gender relations and that adaptation may be more effective when women are involved in meaningful ways. Hence, a nuanced understanding of the gendered nature of intra-household adaptation decision-making is essential for gender-responsive research, policy-making and practice.Objective: This qualitative systematic review aimed to investigate how gender relations influence decision-making concerning climate change adaptation in rural East African households and how decisions about climate change adaptation influence intra-household gender dynamics, in turn.Methods: Applying qualitative meta-synthesis principles, systematic searches were conducted in 8 databases and supplemented with comprehensive hand searches. 3,662 unique hits were screened using predetermined inclusion criteria, leading to a final sample of 21 papers. Relevant findings of these studies were synthesised using inductive thematic coding, memoing and thematic analysis.Results: While men tended to be the primary decision-makers, women exercised some decision-making power in traditionally female domains and in female-headed households. Women’s and men’s roles in intra-household adaptation decision-making appeared to be influenced by a plethora of interconnected factors, including gender norms, gendered divisions of labour and access, ownership and control over resources. Intra-household adaptation seemed to impact the dynamics between male and female household members. The pathways of this influence were complex, and the ultimate outcomes for men and women remained unclear.Discussion: We discuss our findings with reference to theoretical literature on gender-transformative approaches in development and adaptation and previous research concerning the gendered nature of CCA in East Africa. We then discuss implications for gender-responsive adaptation interventions.
Long-term affective and non-affective brain alterations across three generations following the genocide in Cambodia
Authors: Caspar Emilie A. , Pech Guillaume
Published: August 2023

Importance. The literature has largely indicated that trauma can lead to post-traumatic stress disorder (PTSD) and alterations in brain functioning. However, even though research has shown that descendants of parents who have experienced trauma are more prone to developing PTSD symptoms, it remains unclear whether brain alterations are also observable in subsequent generations. Objective. Uniquely, the present project focused on survivors of the Cambodian genocide and their descendants spanning two generations, to determine whether brain alterations are observable about five decades after the traumatic event and in subsequent generations. Design, Setting, and Participants. We conducted a cross-sectional study with a total of 163 participants (Generation 0=59; G1=52 and G2=52). Using portable electroencephalography (EEG), we used four experimental tasks—two targeting non-affective processing (i.e., sensory gating, oddball) and two targeting affective processing (i.e., emotion recognition, threat processing). Post-traumatic stress disorder was assessed using PTSD Checklist (PCL)-5. All tasks were pre-registered before data acquisition. Results. Using both the frequentist and the Bayesian statistical approaches, we found that, although the rate of PTSD symptoms was similar across generations, the affective reaction to threat was primarily observed, or intensified, in the directly affected generation with PTSD. For other tasks, the persistence of affective and non-affective alterations was not statistically reliable.Conclusions and Relevance. The present study underscores that affective and non-affective alterations might be reduced decades after a trauma, but a sensibility to threat remains in individuals with PTSD. Our results also support a dissociation between PTSD and neural alterations.
Overcoming Academic Procrastination: A Behavioral-Cognitive Approach
Authors: Lee Joshua
Published: August 2023

Procrastination, the act of delaying tasks, is an issue affecting individuals regardless of skin color, age, or gender. Notably, a significant proportion of young students in the United States struggle with academic procrastination, and multiple examples are provided with students at the focus. This research paper adopts the lens of a behavioral-cognitive psychology approach, employing both cognitive behavioral therapy (CBT) and operant conditioning to uncover how academic procrastination occurs. Using CBT, the thought process contributing to the behavior, procrastination, is identified, while operant conditioning serves as a tool to unlearn this behavior. The objective of this study was to explore the potential of a behavioral-cognitive approach to prevent one category of academic procrastination: external distractions. Gathering data on how CBT and operant conditioning are applied, a conclusion was formed based from over a dozen credible sources. The study’s findings contain a potential solution, synthesizing a rough model that aims to reduce academic procrastination by unlearning the behavior and addressing the underlying causes. Further exploration on how operant conditioning affects an individual is required to solidify the findings.
Development of an adaptive test of musical scene analysis abilities for normal-hearing and hearing-impaired listeners
Authors: Hake Robin , Bürgel Michel , Nguyen Ninh K. , Greasley Alinka , Müllensiefen Daniel , Siedenburg Kai
Published: August 2023

Auditory scene analysis (ASA) is the process by which the auditory system makes sense of complex acoustic environments through organizing sound mixtures into meaningful events and streams. Although music psychology has acknowledged the fundamental role of ASA in shaping music perception, no efficient test to quantify listeners’ ASA abilities in realistic musical scenarios has been published yet. This study presents a new tool for testing ASA abilities in the context of music, suitable for both normal-hearing (NH) as well as hearing-impaired (HI) individuals: The adaptive Musical Scene Analysis (MSA) test. The test uses a simple ‘yes-no’ task paradigm to determine if the sound from a single target instrument is heard in a mixture of popular music. During the online calibration phase, 525 NH and 131 HI listeners were recruited. The level-ratio between the target instrument and the mixture, choice of target instrument, and number of instruments in the mixture were found to be important factors affecting item difficulty, whereas the influence of the stereo width only had a minor effect. Based on Bayesian logistic mixed effects model, an adaptive version of the MSA test was developed. In a subsequent validation experiment with 74 listeners (20 HI), MSA scores showed acceptable test-retest reliability and moderate correlations with other music-related tests, pure-tone-average audiograms, age, musical sophistication, and working memory capacities. The MSA test is a user-friendly and efficient open-source tool for evaluating musical ASA abilities and is suitable for profiling the effects of hearing impairment on music perception.
Interação entre as caraterísticas do Calçado e o Risco de Queda ao mesmo nível
Authors:   508592151, Santos Mónica , Almeida Armando , Lopes Catarina
Published: August 2023

Introduction/framework/objectives Falls to the same level are reasonably frequent and, if in some professional sectors there is a reasonable number of employees who have access to adequate footwear, in other contexts this does not happen. In addition, not all professionals working in the Occupational Health teams will be able to make recommendations to choose the model to be acquired. The aim of this review was to summarize the most recent and relevant publications on this topic, in order to try to alleviate this issue. Methodology This is a Bibliographic Review, initiated through a search carried out in August 2021 in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Contents Accidents are associated with a decrease in productivity, more indemnities for disability, an increase in the number of days lost from work, more pain/suffering for the employee at the time and, eventually, permanent disability in the future. Falling to the same level will depend on extrinsic or environmental factors (such as weather, light, obstacles, distractions, footwear, tasks per se and floor characteristics) and intrinsic or human factors (joint/muscular and reflex issues-postural stability and fatigue muscle/intense exercise). Discussion and Conclusions Although the selected articles did not produce a synthesis of information that would allow the topic to be approached with much confidence and robust evidence, were found data that could minimally guide the activity of professionals working with employers with this risk factor, namely: providing a adequate illuminance and temperature, eliminate or reduce obstacles, prepare a floor with grooves perpendicular to the main direction of displacement, attenuate or eliminate water or other contaminants, avoid or attenuate the maintained standing posture, as well as vigorous exercise immediately before/fatigue, control the displacement speed and develop joint and muscular strength of the employee. As for the characteristics of the shoe itself, these can be summarized in the existence of deep grooves in the sole, a non-elevated heel, a model that is above the ankle and the use of flexible, light materials with soles that cause adequate friction. It would be pertinent taht some professionals working in Occupational Health to better investigate the topic (differences between models/materials and areas of work/specific tasks; as well as comfort and adherence) and publish the conclusions obtained in journals in the area. Keywords: fall to the same level, non-slip footwear, occupational health and occupational medicine.
Determinação sequencial de Anticorpos IGg Anti-Spike SARS-COV-2 seis meses após infeção Covid-19 em Profissionais de Saúde de um Hospital Central Português
Authors: Matos Sara , Almeida Maria , Duarte Ana , Miranda Mário
Published: August 2023

Introduction Healthcare workers were heavily exposed to repetitive viral loads during the SARS-CoV-2/COVID-19 pandemic. The duration and effectiveness of post-infection immunity remains an unclear question. The determination of serum IgG anti-S/SARS-CoV-2 (IgG/anti-S) antibodies is the only feasible way to assess immunity against this virus. Methods We’ve identified 193 RT-PCR/SARS-CoV-2 positive from a total of 4200 healthcare workers from an university hospital between March-May 2020. Serum IgG/anti-S was determined by chemiluminescence immunoassay in three anonymized quarterly samples to comparison of mean concentrations over the six months of observation (cut-off defined by the manufacturer: ≥1AU/mL). Disease severity was classified as asymptomatic, mild/moderate and severe/very severe. Results 76.2% were infected women, with mean ( ) age 39.6±11.7 year; men mean age 41.1±13.0 years, and women/men ratio 3.2. 93.8% worked in high-risk areas and 72.5% were nurses or assistants. Regarding the severity, 7.8% had asymptomatic infection and 6.7% had serious illness with inpatient management. 8.3% refused to participate on serologic testing, so 177 participants were included. In the first determination, 73.5% had IgG/anti-S(+ve) (144/166 samples) with 12.5±9.1 AU/mL, collected at =50.3±15.3 days after symptoms onset. At the second time, 47.9% (80/167) had positive results, with IgG/anti-S =2.7±4.9 UA/mL, =143.1±43.9 days after symptoms. The third moment had 27.7% positive results, with IgG/anti-S =1.3±2.8 AU/mL, =241.3±75.5 days after symptoms. Discussion A progressive decrease in mean IgG/anti-S titers was evident during the first six months after SARS-CoV-2 infection, in consonance with the available data, with 13% of professionals presenting antibody levels below the threshold of positivity a month and a half after infection, 52% after four and 72% after six months. We also found that even those with positive titers, at six months, approached the cutoff point, showing a downward curve. Conclusions These results suggest that natural immunity is weak/scarce and reinforce that infected professionals should be vaccinated against COVID-19. This measure, together with the protective (collective plus individuals) actions, maximize workers protection against new infections, as well as the safety of patients of the institution.
Student Engagement- An Assessment and Comparison
Authors: Parveen Heema , Jan Kounsar
Published: August 2023

Though student engagement has earned a considerable attention elsewhere in the world but in India it is still an evolving concept. Engagement as a term is based on the idea of participation, identification and investment. It encompasses all the three behavioral, cognitive and affective components. Every component is equally contributing to the total engagement a student reports in an activity or school. A holistic understanding of student engagement is crucial. Its significance and role in promoting positive and better outcomes is immense, making it extremely essential to be paid special emphasize to and analyze the level or extent to which students are engaged in school related activities or report engagement in their respective schools both at state and national level. The present investigation is an attempt to analyze and assess the student engagement among higher secondary students studying in various government schools in the Kashmir province of Jammu and Kashmir UT. 700 higher secondary school students consisting of (339) rural and (361) urban, made up the sample, selected using the probability sampling technique. The Student Engagement Scale developed and constructed by the researcher was used to collect the data. Moreover, a comparative analysis with regard to gender and residence was performed to compare the groups based on these two demographic variables. Statistical procedures such as Mean, percentage, SD and t-test were employed to analyze the obtained data. The results showed, 23.4% of students fall in the high engagement group, 50.1% were averagely engaged and 26.4% were found in the low student engagement category. Moreover, a significant difference was found in the student engagement level of male and female students. The Mean of female students (M=121.44) was higher as compared to male students (M= 116.71) and the difference between means was significant at .01 level (t= 4.198). However, no significant difference was found in the mean score of students residing in urban and rural areas. Students from both the areas had similar mean score on the student engagement scale.
ТЕЛЕБАЧЕННЯ ЯК СОЦІОКУЛЬТУРНИЙ ФЕНОМЕН І ПРЕДМЕТ КУЛЬТУРОЛОГІЧНОГО ДОСЛІДЖЕННЯ
Authors: Цімох Наталія Іванівна , Гнатюк Анатолій Васильович
Published: August 2023

У статті охарактеризовано телебачення як соціокультурний феномен, доведено актуальність застосування культурологічного підходу до його вивчення. Наголошено на помилковості тлумачення телебачення суто як засобу масової інформації, натомість звернено увагу на потребу розгляду телебачення як простору, середовища чи навіть середовищ, в яких продукуються і передаються культурні цінності. Акцентовано, що дослідження телебачення в межах культурології передбачає застосування певних методів і підходів, які, не заперечуючи здобутих досягнень в його вивченні, дали б змогу міждисциплінарно проаналізувати його і як важливу медіаструктуру, і як атрибут глобалізації, і як соціокультурний феномен. Обґрунтовано необхідність невпинного коригування теоретичних положень, що описують певний етап розвитку телебачення та його специфічні особливості, зумовлену складністю, швидкою трансформацією самого об’єкта дослідження. Коротко описано етапи трансформації телебачення: 1) від транслятора популярних творів кінематографа і театрального мистецтва до соціального (сутність якого визначається художньо-розважальним, економічним, інформаційним, політичним і технологічним компонентами, і водночас чинниками, розвитку) та культурно-комунікативного інституту (впливає на сприйняття реальності, на стиль і спосіб життя мільйонів людей); 2) від утилітарного засобу передавання інформації до інструмент ууправління глядацьким сприйняттям, до сенсопороджуючого елемента надскладної системи комунікації у світі. Згадано про інструментарій осмислення феномена телебачення: 1960-ті роки – мистецтвознавчі, 1970-ті – філологічні підходи; 1970–1980-ті – інституційний, 1990-ті – індустріальний підходи; у 2000-х рр. – комунікативний підхід. Підсумовано, що жоден зі згаданих підходів до дослідження телебачення не здатен надати повної інформації не просто про телевізійні програми та їх аудиторію, а й про згадані вище компоненти/чинники функціонування телебачення, що дає змогу отримати саме культурологічний підхід. Акцентовано на взаємозв’язку телебачення із масовою культурою, що є одним із перспективних напрямів культурологічного дослідження - вивчення телебачення як каналу поширення артефактів останньої та як каталізатора процесу масовизації культури.
Adipocytokines Through the Prism of Human Metabolic Phenotypes
Authors:   Research Institute of Internal and Preventive Medicine — Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Alferova V.I. ,   Novosibirsk, Russian Federation, Mustafina S.V. ,   Research Institute of Internal and Preventive Medicine — Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences; Novosibirsk, Russian Federation
Published: August 2023

Aim: To study the features of adiponectin, leptin, resistin, adipsin, interleukin 6, and tumor necrosis factor α levels in individuals with a metabolically healthy and unhealthy phenotype at different values of body weight according to the literature. Key points. The results of foreign and domestic studies of the levels of adipocytokines in metabolically healthy and unhealthy phenotypes in individuals with different body weights are presented. Adipokines such as adiponectin, leptin, resistin, adipsin, interleukin 6, and tumor necrosis factor α were analyzed. Data are given on the pathogenetic and clinical features of the production of these biologically active substances and their effect on metabolism. Conclusion. According to the literature, high levels of leptin, resistin, tumor necrosis factor α, interleukin 6 are associated with a metabolically unhealthy phenotype, and adiponectin, adipsin are associated with a metabolically healthy phenotype. Keywords: adipokines, metabolically healthy obesity, metabolically unhealthy obesity, adiponectin, leptin, resistin, adipsin, interleukin 6, tumor necrosis factor α.
Effect of Dapagliflozin on Fat and Carbohydrate Metabolism in Patients with Type 2 Diabetes Mellitus
Authors:   Russian Medical Academy of Continuous Professional Education, Gogoleva S.P. ,   Moscow, Russian Federation, Ametov A.S. ,   Russian Medical Academy of Continuous Professional Education; Moscow, Russian Federation, Shabalina A.A. ,   Research Center of Neurology; Moscow, Russian Federation
Published: August 2023

Aim: To determine the effects of dapagliflozin in impaired carbohydrate and fat metabolism in type 2 diabetes mellitus (T2DM). Design: An open cohort controlled prospective study. Materials and methods. In this study 60 patients with T2DM and obesity were examined. Dapagliflozin 10 mg was added to metformin monotherapy. Carbohydrate metabolism and fat metabolism markers were evaluated for 6 months: anthropometry, body composition analysis, assessment of adipokines (adiponectin, leptin, irisin, interleukin (IL) 6) and lipid panel. Results. Dapagliflozin addition resulted in glycated hemoglobin level decrease by an average of 0.6% (p = 0.093) along with significant positive effects on fat metabolism markers. The mean body mass decrease was 3.3 kg (p < 0.05). There was also a significant decrease in fat mass of 3 kg (p = 0.001) and a muscle mass extension, according to a body composition analysis report, which correlated with leptin levels decrease (p = 0.073) and adiponectin and irisin levels increase (p < 0.05). A significant decrease in total cholesterol, triglycerides and low-density lipoproteins levels also occurred (p = 0.001). Conclusion. Leptin and IL-6 levels decrease and irisin and adiponectin levels increase correlating with a fat mass reduction and muscle mass expansion occurred with dapagliflozin added to the therapy. These findings suggest the possibility of metabolically unhealthy obesity transitioning to metabolically healthy obesity. Adipose tissue dysfunction treatment as a focus of therapy may provide not only a better control of T2DM, but also cardiometabolic risks reduction. Keywords: type 2 diabetes mellitus, dapagliflozin, adiponectin, leptin, irisin, interleukin 6, lipid panel, fat metabolism.
Rheumatological Masks of Hypothyroidism
Authors:   I.M. Sechenov First Moscow State Medical University (Sechenov University), Mikhalkova D.Yu. ,   Moscow, Russian Federation, Vitebskaya A.V. ,   I.M. Sechenov First Moscow State Medical University (Sechenov University); Moscow, Russian Federation
Published: August 2023

Aim: To demonstrate clinical cases of hypothyroidism in adolescents manifested under the guises of rheumatic diseases. Key points. We presented the cases of hypothyroidism which required differential diagnostics with systemic lupus erythematosus (SLE) and juvenile idiopathic arthritis (JIA). Thyroid arthropathy course is demonstrated. Conclusion. Hypothyroidism is characterized by nonspecific symptoms (weakness, oedema) which are also typical for SLE and JIA; thyroid hormones measurement for diagnostics is necessary. If joint syndrome remains in spite of hypothyroidism compensation repeated differential diagnostics of thyroid arthropathy and JIA is required. Keywords: adolescents, hypothyroidism, juvenile arthritis, systemic lupus erythematosus, thyroid arthropathy.
Exploring Pan-African Unity and Development in Yoruba Arabic Literature
Authors: Sarumi Kahar Wahab
Published: August 2023

This article examines the theme of Pan-Africanism in Yoruba literature in Arabic and analyzes the perspectives of Yoruba literati on how unity of the African nations and leaders could function in evolving a new Africa that would withstand socio-economic and political challenges. The article investigates the following questions: how might the views and insights of Yoruba writers and critics benefit Africa in achieving unity for development? And how might Yoruba Arabic literature on Pan-Africanism contribute to switching and shifting the paradigm of development in Africa? To provide answers to these questions, I selected the works of three Yoruba Arabic scholars namely, Adam al-Ilorī, Isa Abu-Bakre and Abdul Aziz Azakawī for analysis. The article benefits in its discussion from historical, descriptive and analytical methods. Employing several historical and analytical methods, the article draws on some of the views of prominent Pan-Africanist intellectuals such as Du Bois, Kwame Nkrumah, Nelson Mandela, Julius Nyerere, Frantz Fanon, Chinua Achebe and Wole Soyinka among others. I argue that the selected Yoruba Arabic writers consider unity as vital to the economic, social and political progress of Africa just as requisite ingredients for its renaissance.
Jan Kochanowski’s Psalter – a Source of Polish Poetry and Mirror of the Human Mind
Authors: Buszewicz Elwira
Published: August 2023

The article deals with Jan Kochanowski’s Psałterz Dawidów [David’s Psalter], published in 1579. This paraphrase of the biblical Psalter, intensely lyrical in its spirit, was inspired by George Buchanan’s Latin poetic paraphrase of the Psalms, which is strongly Horatianising. Kochanowski’s work can be seen as a presentation of humanist piety. That is to say that the borders between secular and sacred spaces, or even between Judeo-Christian and Pagan traditions, may seem blurred. The Psalter is also interconfessional (or “doctrinally neutral”) and acts as a universal mirror reflecting the human mind. The author analyses three of Kochanowski’s Psalms to demonstrate the intellectual and emotional space of his Psalter and its polyphonic structure: 1 (Beatus vir qui non abiit in consilio impiorum), 19 (Caeli enarrant gloriam Dei) and 91 (Qui habitat in adiutorio Altissimi), displaying some interplays of ideas and different approaches to paraphrasing applied by the poet.
The Covenants of the Patriarchs with Foreigners at Beersheba
Authors: Dziadosz Dariusz
Published: August 2023

The author of this paper seeks the original historical context as well as the oldest form, structure and concept of the biblical records of the covenants of Abraham and Isaac with the local ruler(s) as recorded in Gen 21:22–24, 25–33; 26:26–31. The patriarchs, who enjoy the status of foreign/sojourner/ resident in the land of the Philistine king, Abimelek, and their peaceful agreements are depicted in three biblical sources, which are very similar to each other in terms of structure and literary context. Those are compared with selected Hittite, Babylonian and Assyrian records of the royal covenants from the 2 millennium BC. The methodology adopted in the research allowed several important formal and substantive points of contact to be noted in the compared sources. Through this comparison, the paper confirms that Gen 21:22–24, 25 33; 26:26–31 reflects two ancient patterns of bilateral covenants between the monarch and an equal or subordinate social partner: royal grants and suzerain-vassal treaties. The paper also discusses the socio-cultural and legal spectrum of the Near Eastern royal procedures and how they were re-edited and adapted by the editors responsible for the current version of the biblical cycles about the patriarchs.
Особливості спадкування неповнолітніми особами в країнах Європейського союзу – порівняльно-правовий аналіз
Authors: Kurylo Tetyana , Barankevych Anna
Published: August 2023

Метою проведеного дослідження є порівняльна характеристика норм спадкового права країн Європейського союзу в площині спадкування неповнолітніми особами та викладення власного бачення авторів щодо доцільності імплементації певних правових норм у національне законодавство України. Така порівняльна характеристика дозволить виокремити ті правові конструкції, які можуть бути застосовані в українському законодавстві для забезпечення охорони та захисту якнайкращих інтересів неповнолітніх спадкоємців. В статті проведено аналіз законодавства країн Євросоюзу, яке визначає правовий статус неповнолітніх осіб як спадкоємців, виокремлено правові інститути та конструкції, які доцільно впровадити в національне законодавство України для забезпечення охорони та захисту спадкових прав неповнолітніх осіб.
MOLECULAR DOCKING INVESTIGATIONS OF THIOSEMICARBAZONE Cu(II) and Zn(II) METAL COMPLEXES AGAINST EGFR, HER2, AND IKK-β TARGET PROTEINS: SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL SCREENING
Authors: Mekala Himabindu , Palabindela Rambabu , Myadaraveni Prabhakar , Banothu Devendar , Ravi Gangalla , Kasula Mamatha
Published: August 2023

Cu(II) and Zn(II) complexes of Schiff bases produced from thiosemicarbazone with Anthracene, indole, pyrimidines, and chromones have been synthesized and physiochemically characterized. Among the synthesized ligands L1-L4, the first three ligands behave as uninegative bidentate ones towards Cu(II) and Zn(II) metals, whereas the L4 ligand behaves as a uninegative tridentate one. The structure and bonding properties of the complexes have been investigated using electronic and HRMS-spectral data. All the ligands and complexes were tested for their anti-cancer and anti-bacterial activities. Docking studies demonstrated that Cu(II) and Zn(II) complexes interacted favorably with the EGFR, HER2, and IKK-β receptors.
PREPARATION AND CHARACTERIZATION OF ACTIVATED CHARCOAL FROM BAMBOO WASTE WITH PHOSPHORIC ACID AS A BIOSORBENT FOR RHEMAZOL BRILLIANT BLUE
Authors: M. Manurung  , I. E. Suprihatin  , O. Ratnayani
Published: August 2023

Bamboo waste can be converted into materials of high economic value when processed into activated charcoal which is useful as an adsorbent. This study aims to make activated charcoal from bamboo waste with 20%(w/v) phosphoric acid as an activator. The activated charcoal produced was used as an adsorbent for rhemazol brilliant blue dye. Characterization of activated and inactivated charcoal was carried out by referring to the Indonesian National Standard-1995. Contact time and pH were studied for optimizing the adsorption. The results showed that the optimum contact time was 60 minutes, and the pH of the solution was 2. Isotherm adsorption of both charcoals tends to follow Langmuir isotherm, and the adsorption capacity obtained was 12.2399 and 9.5697 mg/g for activated and nonactivated charcoals respectively. Adsorption kinetic charcoals follow to pseudo-second order. Both charcoals are thought to contain functional groups of hydroxy, carbonyl, and aliphatic double bonds and have heterogeneous surfaces.
SYNTHESIS OF ZINC OXIDE NANORODS USING Ficus benghalensis AERIAL ROOT EXTRACT AND ITS ENHANCED ANTI-INFLAMMATORY AND ANTIBACTERIAL ACTIVITIES AGAINST DENTAL BACTERIA
Authors: V. Nandhakumar  , Gracia J. Princess , Richard J. Prince , N. Balasubramanian  , Suganya G.
Published: August 2023

High-purity Zinc Oxide and Ficus benghalensis – Zinc Oxide Nanorods were developed by hydrothermal method. The physio-chemical characteristics of the Nanorods were investigated. X-ray Diffraction spectrum confirms the formation of well crystalline nanorods along (101) orientation. The particle size of as-synthesized Nano rods was noticed to be lesser than the chemically synthesized Zinc Oxide nanorods. The PL spectrum shows a broad red emission peak and a sharp blue emission peak. The width of the energy gap of nanorods is lesser than the chemically synthesized ones. The functional groups of the Nanorods were determined by Fourier Transformation Infrared analysis. Scanning Electron Microscope-Energy Dispersive X-ray analysis micrograph reveals the morphology of the nanorods and elements present. The antibacterial and anti-inflammatory efficiency of the Nanorods were evaluated by the Agar well diffusion method against some multi-drug safe oral microbes and the Bovine serum albumin (BSA) denaturation method.
PHYSICAL RESPONSE OF ACRYLIC RESIN IN EFFECT OF Ziziphus mauritiana LAM RELATED TO GROWTH AND BIOFILM FORMATION OF Candida albicans
Authors: O. Fadriyanti  , W. Widyawati  , B. A. Gani
Published: August 2023

This study evaluated the potential of Ziziphus mauritiana Lam (Z. mauritiana Lam) ethanol extract improves thermal stability and strength to prevent the growth and biofilm formation of C. albicans.The assessment of heat release (thermal equilibrium) of acrylic resin using Differential scanning calorimetry, the strength of acrylic resin with the universal testing machine, growth assessment of C. albicans by spectrophotometry, and biofilm assay with crystal violet and visual images used to a microscope. Z. mauritiana Lam 12.5% provides better thermal stability with a cooling peak enthalpy of -223.27 cal/g. In addition, concentrations of 6.25% and 3.125% at 48 hours had a better ability to increase the strength of acrylic resin (p>0.05). Z. mauritiana Lam at all concentrations and incubation of 24 and 48 hours were similar in decreasing the growth of C. albicans (0.06-0.08 or equivalent to 0.05). The Z. mauritiana Lam increased heat release (thermal stability) in acrylic resin, which caused an increase in transverse strength. At the same time, it reduces the growth and biofilm formation of C. albicans on the acrylic resin surface.
PHOTOCATALYTIC DEGRADATION OF CONGO RED USING BISMUTH VANADATE-NICKEL SULPHIDE COMPOSITE
Authors: J. Panwar  , L. Joshi  , R. Ameta  , D. Soni
Published: August 2023

A composite of BiVO4-NiS was synthesized and used as a photocatalyst for the photocatalytic degradation of Congo red dye. BiVO4 and NiS were mixed in a 1:1 ratio. The composite was characterized on the basis of XRD, EDX, and FESEM data. The progress of photocatalytic degradation was monitored with a spectrophotometer. The effects of different parameters such as pH, dye concentration, amount of composite and light intensity on the degradation rate were investigated. The composite exhibited the highest catalytic activity in a neutral medium. It was found that higher activity, more stable nature, and recyclability of BiVO4-NiS composite were beneficial for the photodegradation of Congo red dye.
GREEN SYNTHESIS OF COPPER NANOPARTICLES FROM AN EXTRACT OF CINNAMON BARK: SPECTROSCOPIC CHARACTERIZATION, OPTICAL PROPERTIES, ANTIMICROBIAL, AND ANTIOXIDANT ACTIVITIES
Authors: Kothari Richa
Published: August 2023

Nanobiotechnology is increasing at a very fast rate due to its various industrial applications in the textile, biomedical, food, pharmaceutical, and paint industries. The green synthesis of copper nanoparticles using an aqueous extract of cinnamon zeylanicum has been documented in our present research work. The green synthesis of Cu NPs is a very simple, fast, efficient, eco-friendly, and cost-effective method. In this work, we use an aqueous environment for the green synthesis of copper nanoparticle(Cu NPs). The aqueous environment plays a very important role in decreasing reaction time, reducing the minimum possibilities of side reactions, and proper conversion of precursors into good quality CuNPs in very less time. The existence of flavonoids, tannins, glycosides, and alkaloids was confirmed by the phytochemical analysis of the plant extract, and the presence of these chemicals can be used as reducing, stabilizing, and capping agents. The Cu NPs were characterized by structural, vibrational, and electronic spectroscopic techniques. Powdered X-ray diffraction studies confirm the formation of well-defined equispaced crystalline CUNPs. The average particle and crystalline size of CuNPs were found to be 66.16 ±1 nm and 77.54±1 nm respectively. The Surface plasmon resonance peaks were found at 233.67 and 252.2 nm, measured using UV-Visible spectroscopy, and the calculated band gap was found to be 3.5 e V at 288nm, indicating the semiconductor behavior of the CZ-CUNPs. The effective results of pharmacological activities of CuNPs due to the presence of flavonoids, tannins, glycosides, and alkaloids in the CZ bark extract. The green synthesis of CZ-CUNPs from an aqueous extract of cinnamon zeylanicum bark in the proper stoichiometric ratio is an excellent method for synthesizing highly effective bioactive agents which can be considered good drug candidates for various biomedical applications in the future for mankind.
EXPLORING THE ROLE OF A BIO-SURFACTANT IN THE STABILIZATION OF HIGHLY CONCENTRATED IRON ORE SLURRY
Authors: Das Subrata Narayan , K. Biswal Susanta , K. Mohapatra Ranjan
Published: August 2023

The formulation and stabilization of highly concentrated solid-water slurry for transportation are gaining high interest. The influence of saponin extracted from A. auriculiformis on the stabilization of a high-grade iron ore sample in the slurry was studied. The collected iron ore powder and dried iron ore slurry samples were compared with the help of UV-vis, XRF, XRD, SEM, and EDS analysis. Moreover, the DSC spectral graph for both heat flow and mass loss with respect to time is plotted. The results confirmed that the surfactant molecules (aqueous A. auriculiformis) coated well on the iron surface which form an effective barrier between the iron ore particles. Further, the solubility of iron ore powder increased after adding an aqueous extract of Acacia auriculiformis as evident from the UV-vis spectral study.