bluuebunny/crossref_metadata_2025 huggingface dataset:
Zebrafish Larvae as an in vivo Model for Antimicrobial Activity Tests against Intracellular Salmonella
Authors: Hauswirth Patrick , Buck Jonas , Puligilla Ramya , Alter Claudio Luca , Sieber Sandro , Claudi Beatrice , Fanous Joseph , Bumann Dirk , Huwyler Jörg
Published: May 2023

Introduction: Blood infections from multi-drug-resistant Salmonella pose a major health burden. This is especially true because Salmonella can survive and replicate intracellularly, and the development of new treatment strategies is dependent on expensive and time-consuming in vivo trials. The aim of this study was to develop a Salmonella-infection model that makes it possible to directly observe Salmonella infections of macrophages in vivo and to use this model to test the effect of antimicrobials against intra- and extracellular Salmonella in order to close the gap between in vitro and rodent-infection models. Methods: We established suitable Salmonella-infection conditions using genetically engineered zebrafish and Salmonella-expressing fluorescent proteins (green fluorescent protein (GFP) and/or mCherry). Results: We detected Salmonella inside and outside zebrafish larvae macrophages. Administration of the cell-impermeable antibiotic tobramycin removed Salmonella residing outside macrophages but did not affect Salmonella in macrophages, whereas ceftriaxone successfully cleared both types of Salmonella. Salmonella inside and outside macrophages experienced substantial DNA damage after administration of fluoroquinolones consistent with the excellent cell penetration of these antibiotics. Conclusions: The zebrafish-larvae model enables testing of antimicrobials for efficacy against extra- and intracellular Salmonella in a complex in vivo environment. This model thus might serve for antimicrobial lead optimization prior to using rodent models.
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis
Authors: Xiong Dan , Hu Wei , Han Xiaofang , Cai Yahong
Published: May 2023

Background: Diabetic nephropathy (DN) is one of the most serious complications of diabetes. Rhein has been reported to be effective in treating DN. This study aimed to investigate the role and mechanism of rhein in the treatment of DN. Methods: High glucose-induced (HG) podocyte injury model and streptozocin-induced (STZ) DN mouse model were constructed and intervened with rhein. Cell viability was detected by Cell Counting Kit-8 (CCK-8) assay. The reactive oxygen species (ROS) level was measured by flow cytometry. The expression of Ras-related C3 botulinum toxin substrate 1 (Rac1), NADPH Oxidase 1 (NOX1), and β-catenin were measured by quantitative real-time PCR (RT-qPCR). The contents of glutathione peroxidase 4 (GPX4), α-smooth muscle actin (α-SMA), Nephrin, and Podocin were characterized by immunofluorescence (IF) staining. Hematoxylin-eosin (HE) staining and Masson staining were employed to observe the renal morphological changes and tubulointerstitial fibrosis. The contents of α-SMA and Nephrin were detected by immunohistochemistry (IHC) staining. The kits were utilized to analyze various biochemical indicators. Results: Rhein inhibited the HG-induced accumulation of ROS, malondialdehyde (MDA), and Fe2+, and the expression of α-SMA, Transferrin Receptor 1 (TFR1), acyl-CoA synthetase long-chain family member 4 (ACSL4), Vimentin, Snail, and Desmin. Rhein inhibited the expression of Rac1 and its downstream targets NOX1 and β-catenin. Rac1 silencing (si-Rac1) inhibited the accumulation of MDA and Fe2+ and the expression of Rac1, NOX1, β-catenin, α-SMA, TFR1, and ACSL4. Rac1 overexpression (oe-Rac1) resulted in the inhibition of superoxide dismutase (SOD), glutathione (GSH), GPX4 synthesis, and down-regulation of Recombinant Solute Carrier Family 7, Member 11 (SLC7A11) and Nephrin expression in HG-treated podocytes. Rac1 Lentivirus (LV-Rac1) injection significantly promoted the accumulation of MDA and Fe2+ and increased the expression of RAC1, NOX1, β-catenin, TFR1, ACSL4, and α-SMA in DN mice. Conclusions: Rhein inhibited ferroptosis and epithelial-mesenchymal transition (EMT) to attenuate DN by regulating the Rac1/NOX1/β-catenin axis.
Promoting Sustainable Development: The Role of Environmental Law and International Cooperation
Authors: Butt Aaliya
Published: May 2023

Promoting Sustainable Development: The Role of EnvironmentalLaw and International Cooperation
Protecting Biodiversity: Legal Frameworks for Conservation and Ecosystem Preservation
Authors: Butt Aaliya
Published: May 2023

Protecting Biodiversity: Legal Frameworks for Conservation andEcosystem Preservation
Efektivitas Penggunaan Model Pembelajaran Cooperative Script
Authors: Rif'ah Athiyyah Taqhilah
Published: May 2023

Penerapan model pembelajaran Cooperative Script dalam pelaksanaan kegiatan pembelajaran berguna untuk menumbuhkan ide - ide atau gagasan baru dalam pemecahan suatu masalah, pengembangan daya berpikir kritis serta mengembangkan mentalitas dan melatih public speaking peserta didik dalam menyampaikan hal - hal baru yang diyakininya benar. Model pembelajaran ini merupakan suatu cara bekerja sama dalam membuat naskah tulisan tangan dengan berpasangan dan bergantian secara lisan menyimpulkan materi - materi yang sedang dipelajari sehingga dapat meningkatkan pemahaman peserta didik mengenai konsep materi pembelajaran yang sedang diajarkan oleh tenaga pendidik.
Russian Prosody as a Special Case of the Mobile Stress System in Indo-European Languages
Authors: Comstock Lindy B
Published: May 2023

Redundancy is a key element of linguistic systems, serving to constrain variation in features that convey an important function within the system (Winter & Wedel, 2016). This redundancy may counteract phonological change and preserve the intelligibility of speech (see Ohala, 1989). Derivational processes are one means by which dual representational systems may be acquired, particularly in unmarked linguistic structures (Kiparsky, 2003). Russian adjectival suffixes present an interesting problem. Highly regular and resistant to phonological change (Bratishenko, 2019; Hamilton, 1976), Russian adjectival suffixes are typically unstressed and pronounced with phonetic vowel reduction, yet they are perceived to bear pitch accents (Yokoyama, 2001). This paper proposes that the intersection of phonological and morphological features found in Russian adjectival suffixes (i) forms a dual representational system that preserves word-internal metrical structure, and (ii) sheds light on unexplained features of Russian prosody.
Consumer Protection Laws: Ensuring Fair Practices in Commercial Transactions
Authors: Nathan Zofia
Published: May 2023

Consumer Protection Laws: Ensuring Fair Practices in CommercialTransactions
Bard on the hijacked journals with web domains expiring
Authors: wikiarchiving
Published: May 2023

Bard on the hijacked journals with web domains expiring
Bard on the costs of Hindawi's closure of four journals
Authors: wikiarchiving
Published: May 2023

Bard on the costs of Hindawi's closure of four journals
Pre-Registered Analysis Plan: Is the Inter-Researcher Variability in Social Scientific Results Explicable? An Adversarial Collaboration and Joint Effort to Parse Model and Estimate Dispersion
Authors: Breznau Nate , Auspurg Katrin , Brüderl Josef , Holzmeister Felix , Nilsonne Gustav , Aczel Balazs , Clark Cory J , Nguyen Hung Hoang Viet , Varga Marton Aron , Uhlmann Eric Luis
Published: May 2023

We plan a collaborative research analysis of the original ‘many analysts’ study by Silberzahn et al.1 testing whether European soccer referees were skin-tone biased in giving red cards. Their study concluded that the answer has great model dependency, and in this sense is unclear. Auspurg and Brüderl2 re-analysed the methods and data and argued the answer is clearer when attending to causal inference and outliers. Researchers involved in the original study and follow-up agreed to an adversarial collaboration to better answer this pertinent research question and sources of variability in answers. They recruited other scholars to provide independent methodological and theoretical insights. The result is this study where together we jointly tackle the skin-tone bias hypothesis and the ‘parsing problem’ of identifying meaningful moderators that explain effect size dispersion across a multiverse of alternative specifications. We build on Auspurg and Brüderl’s proposal that analysts in the original study had very different interpretations of the conceptual research question, leading them to different empirical research questions, which in turn produced results that are not directly comparable. This pre-analysis plan describes our motivation, methods, and plan to contextualize our findings in larger discussions of race bias, multiverse analysis parsing, and subjectivity in science.
The replication crisis has led to positive structural, procedural, and community changes
Authors: Korbmacher Max , Azevedo Flavio , Pennington Charlotte Rebecca , Hartmann Helena , Pownall Madeleine , Schmidt Kathleen , Elsherif Mahmoud Medhat , Breznau Nate , Robertson Olly May , Kalandadze Tamara , Yu Iris Shijun , Baker Bradley James , O'Mahony Aoife , Olsnes Jørgen Ø.-S. , Shaw John J , Gjoneska Biljana , Yamada Yuki , Röer Jan Philipp , Murphy Jennifer , Alzahawi Shilaan , Grinschgl Sandra , Oliveira Catia Margarida , Wingen Tobias , Yeung Siu Kit , Liu Meng , König Laura M , Albayrak-Aydemir Nihan , Lecuona Oscar , Micheli Leticia , Evans Thomas Rhys
Published: May 2023

The emergence of large-scale replication projects yielding successful rates substantially lower than expected caused the behavioural, cognitive, and social sciences to experience a so-called ‘replication crisis’. In this Perspective, we reframe this ‘crisis’ through the lens of a credibility revolution, focusing on positive structural, procedural and community-driven changes. Second, we outline a path to expand ongoing advances and improvements. The credibility revolution has been an impetus to several substantive changes which will have a positive, long-term impact on our research environment.
The reflection of the mathematical dimension of gambling in iGaming content: A qualitative analysis - Technical report no. 3
Authors: Barboianu Catalin
Published: May 2023

The current technical report of the research project investigating how the mathematical dimension of gambling is reflected in the communication and texts associated with the gambling industry raises the problem of the adequacy of sampling and proposes a new approach in this respect. The qualitative analysis of the reviewed websites is extended to a deeper analysis of language and also to the organization and structure of websites’ content. Although not stated as a goal of the initial project, the research will also try to identify relationships between the specificity of content relative to the mathematical dimension of gambling, and the management and marketing of the website. An overview of the results of the statistical analysis of the current sample is also presented.
Latent Classes of Perceived Societal Marginalization
Authors: Bollwerk Michael , Wetzel Eunike , Schlipphak Bernd , Back Mitja D
Published: May 2023

Previous research has followed a binary perspective in analyzing the effects of modernization and globalization, often assumed to produce the societal camps of both “winners” and “losers” in economic, cultural, and political terms. However, our understanding of these individual differences and the social groups that perceive themselves as disadvantaged by society is still limited. Hence, in contrast to previous findings we argue that the phenomenon may be better grasped by following a “pattern approach”. Hence, in three different samples (total N = 2,566), we applied Latent Class Analysis to investigate subgroups representing individual differences in Perceived Societal Marginalization (PSM). Furthermore, we explored sociodemographic, personal-resource-related, attitudinal, and personality determinants of people’s class membership probabilities to better understand the subgroups – or: patterns – we identified in substantive terms. In the discussion, we focus on the implications of our findings regarding societal cleavages, prejudice toward minority groups, and the support of far-right political parties.
Estimating vital signs remotely using adaptive facial regions for photoplethysmography
Authors: VERMA AAKASH , kaur Gurkirat , Zapana Bruno Daniel Olivera , Yi  , Reid Shawn
Published: May 2023

Traditional approaches to automatic recognition of human emotions have traditionally relied on using sensors placed on the body to collect physiological data. However, recent studies have shown that it is possible to estimate heart rate by analyzing changes in RGB color during the cardiac cycle in video footage of human faces. This process, called photoplethysmography (PPG) signal extraction, allows for con- tactless measurement. In this study, a pioneering method is introduced for classifying human emotions using contactless PPG signals. Various techniques for extracting PPG signals were tested on a widely used emo- tional database. For classification, a deep learning architecture combining a 1D convolutional neural network (1DCNN) and a long short-term mem- ory (LSTM) was employed. The method demonstrated excellent perfor- mance in binary classification of valence and arousal when using 5-second signal segmentation. It is important to note that the primary aim of this study is to present a new technique for automatically recognizing emo- tions by utilizing deep learning and contactless sensing of physiological signals.
Mangrove Land Suitability Assessment Using Weighted Linear Combination: A Case Study of La Union Province Coastline, Philippines
Authors: Aduana-Alcantara Alexis Ann , Almadrones-Reyes King Joshua , Dagamac Nikki Heherson A.
Published: May 2023

Land suitability assessments play a crucial role in determining optimal land use patterns to meet specific requirements, particularly in the context of forest restorations and plantations. However, there is a lack of studies reporting such assessments for mangrove rehabilitation and reforestation in the Philippines, leading to low survival rates (10-20%) due to improper site selection and site-species matching. This study aims to identify and narrow down suitable sites for mangrove growth in La Union Province, facilitating ground truthing for site selection and species matching. The Geographic Information System (GIS) method, specifically the Weighted Linear Combination (WLC) using ArcMap software, was employed. The study identified four suitable sites along the coastline of La Union within the jurisdictions of Aringay, Bangar, Sto. Tomas, and the City of San Fernando, all actively involved in mangrove conservation. However, mangrove planting efforts in other municipalities along the coastline of La Union, such as Agoo, Balaoan, and Bauang, were not reflected on the maps due to data resolution limitations. Nevertheless, the study's findings should be regarded as a supportive tool in the site determination process, with ground truthing and assessment remaining essential. Integrating the study's results with mangrove rehabilitation/reforestation efforts offers efficiency options that have the potential to enhance project success rates.
Partial Replacement of Coarse Aggregates with Plastic Waste in Paver Blocks
Authors: Olubunmi Adetoye , Olamoju Rabiu Olayemi , Taiye Afolayan
Published: May 2023

Plastics are widely used worldwide, but their non-biodegradable nature leads to significant waste generation. Improper management of plastic waste poses environmental hazards. Paver blocks made of concrete offer versatility, aesthetic appeal, and low maintenance when manufactured and placed correctly. Utilizing plastic as a building material aligns with Sustainable Development Goals. Concrete production contributes to the depletion of natural resources like aggregates. This study investigates the partial replacement of coarse aggregates with plastic waste in pavement blocks, using a mix ratio of 1:2:4. Coarse aggregates were replaced at volumes of 0%, 5%, 10%, and 15%. After batching and mixing, 54 cubes were produced and cured for 7, 14, and 28 days. Tests conducted included slump, compressive strength, and water absorption. The results indicate an optimal replacement of 10% of coarse aggregates with plastic waste which reduced water absorption. Plastic waste is recommended for use in low-load bearing walls and structures like pedestrian footpaths and water retaining structures, reducing costs and conserving natural resources. Effective utilization of plastic waste in the construction industry benefits the environment.
Implementation Strategies for Modular Construction Systems in Developing Countries: Perspectives of Nigerian AEC Professionals
Authors: Bello Abdulkabir Opeyemi , Ihedigbo Kingsley Sunday , Bello Taofiq , Awwal Hamzat Mohammed
Published: May 2023

This study aimed to develop effective strategies for implementing Modular Construction Systems (MCS) in developing countries, with a specific focus on the perspectives of Nigerian Architecture, Engineering, and Construction (AEC) professionals. A quantitative research approach was adopted, involving a survey of 227 AEC professionals in Nigeria. The survey collected respondents' perceptions on the developed MCS strategies in developing countries using a structured five-point Likert scale questionnaire. The professionals were identified through a snowball sampling technique. The results indicated that all fourteen hypothesized strategies were statistically significant for implementing MCS in developing countries. The strategies that received the highest mean scores were "Increasing awareness among professionals and stakeholders," "Creating an enabling environment within the industry," and "Government participation in the usage of MCS." The Kruskal-Wallis test revealed that professionals, regardless of their varied professions, held similar opinions on the identified strategies. The study has practical implications for the AEC industry in developing countries by providing valuable insights into strategies for implementing MCS. It can also assist policymakers in making informed decisions. Overall, this study offers a pathway for implementing MCS, addressing the housing shortage, and improving the quality of housing in developing countries.
Assessment of Landcover Change of Kathmandu District, Nepal
Authors: Lama Bimala , Kumpakha Basanti
Published: May 2023

It is necessary to understand land cover changes for managing and monitoring natural resources and development, especially urban planning. Remote sensing and geographical information systems (GIS) are proven tools for assessing land use and land cover changes, which helps planners advance sustainability. Google Earth Engine is used in this study to detect land cover changes in one of the rapidly growing cities in Nepal. It was discovered that from 2013 to 2019, 0.26% of the total area was increased by forests, 3.28% by settlement, 0.015% by wetland, and 1.21% by otherland. The overall accuracy and kappa coefficient of the landcover change study for 2013 are 80% and 0.74, and the overall accuracy and kappa coefficient of the study of landcover change for 2019 are 83.33% and 0.78. The status of the landcover change in Kathmandu district before and after the earthquake showed that forest covers the highest area, followed by cropland, and then settlement in both years 2013 and 2019. Forest, settlement, wetland, and other land have increased by 0.26%, 4.54%, 0.015%, and 1.21%, respectively. However, cropland and grassland have been decreased by 3.28% and 0.22% respectively.
Can GNSS Derived Height Replace Levelling Height? - A Case of Low-Land of Nepal
Authors: KC Shanker , Bhandari Stallin , Upadhyaya Sandesh , Shrestha Sanjeevan
Published: May 2023

Orthometric height is the generally adopted type of height worldwide and in geomatics community. Precise levelling has been the method of obtaining orthometric height in past for most of the country, so as the Nepal. However, due to wide usage of Global Navigation Satellite System (GNSS), the alternative approach of combining GNSS derived ellipsoidal height with geoid undulation to get GNSS derived orthometric height, has been used extensively. In Nepal, this technique was officially adopted in 2020 for Everest height measurement and understood as the efficient way to comply with levelling height. In this study, GNSS surveying was conducted on 15 stations located at the lowland region of Nepal and orthometric heights were obtained from GNSS and geoid method. When compared GNSS derived orthometric height with precise levelling height, the difference remained within threshold of 5cm for majority of observation stations. However, these differences are not sufficient to support the standards set for the third order levelling by Survey Department (SD). The accuracy of GNSS derived orthometric height can be significantly affected by various environment and existing resources such as existing accuracy of geoid, nature of precise levelling height. Considering the revisit upon these conditions, we expect GNSS-levelling as a strong alternative to time consuming, tedious, and costly precise levelling which is most suitable method of obtaining orthometric height in lowland topography at a precision less than 4 cm.
Restoration of Land Parcels using Land Consolidation & Readjustment: A Case of Resilience after Flood Disaster
Authors: Dahal Tanka Prasad , Dangol Susheel , Nepali Purna Bahadur , Shrestha Reshma
Published: May 2023

Millions of people are affected from natural disaster leading to loss of land tenure around the world. People affected from the disaster leading to loss of land tenure are often excluded from post disaster assistance. The parcel boundary may change or obliterated because of disaster or also from some infrastructure development. Re-establishing of the cadastral boundary is very crucial and challenging task to re-establish the tenure rights and other cadastral details. This paper focuses on the restoration of land parcels after flood. Paper highlights the impact of flood in parcel boundary and proposes a concept for restoration of those obliterated parcels of Melamchi bazar, Sindupalchok, Nepal which was affected from the flash flood on 15th June 2021. The model for restoration of land parcel using the concept of land consolidation and re-adjustment has been recommended focusing on land pooling, creating a regular shape of the parcel. This paper also evaluates the current legal provisions for restoration of land parcels after land use change due to flood.
Podstawa prawna sporów sądowych w odniesieniu do umów międzynarodowych zawartych przez Unię Europejską z Kazachstanem i Armenią
Authors: Kalicka-Mikołajczyk Adriana
Published: May 2023

In the context of inter-institutional litigation concerning the legal basis of the European Union acts which have a constitutional significance, cases which call into question the dividing line between the external action of the European Union in areas covered by the Treaty on the Functioning of the European Union and the Common Foreign and Security Policy enshrined in the Treaty on European Union have become increasingly important following the entry into force of the Treaty of Lisbon. The two cases under review constitute a new stage in the dispute between the European Commission and the Council of the European Union concerning the appropriate legal bases for the conclusion and implementation of the “new generation” partnership agreements. In both cases, the Court of Justice of the European Union was called upon for the first time to rule on the demarcation between the competences falling within the Common Foreign and Security Policy and the competences falling within the Treaty on the Functioning of the European Union in the context of the implementation of one of these agreements, specifically with regard to the adoption of a decision under Article 218(9) of the Treaty on the Functioning of the European Union, by which the Council establishes the European Union’s position within the body set up pursuant to that agreement. The Court of Justice of the European Union therefore had to rule whether the position taken by the European Union with regard to decisions taken in an international body is to be determined by the Council unanimously or by qualified majority in accordance with Article 218(9) of the Treaty on the Functioning of the European Union. This issue is of utmost importance as the decision-making system of the Council of the European Union depends on its determination.
ANALISIS FORMULA NUGGET TAHU, UBI JALAR KUNING, BROKOLI UNTUK BALITA WASTING
Authors: Umasangaji M. Sadli , Theresia Theresia , Fajar Ibnu
Published: May 2023

Latar Belakang: Wasting merupakan masalah balita berkaitan dengan asupan gizi yang kurang dan adanya penyakit penyerta atau penyakit infeksi. Hal sebagai penyebab langsung. Wasting dinilai menggunakan indeks antropmetri Berat Badan Menurut Tinggi Badan atau Panjang Badan dengan nilai z-score dibawah -2 SD. Data Riskesdas Tahun 2018 juga menunjukkan Balita Kurus dan Sangat Kurus masing-masing adalah 6,7% dan 3,5% sedangkan data gabungan sebagai data Wasting menunjukkan sebanyak 10,2% Dalam mengatasi Wasting dilakukan pembuatan nugget ini dengan tujuan penelitian ini adalah menganalisis mutu gizi, mutu protein, uji organoleptik serta penentuan taraf perlakuan terbaik terhadap formula nugget tahu, ubi jalar kuning dan brokoli. Metode: Penelitian ini merupakan penelitian eksperimen yang menggunakan desain Rancangan Acak Lengkap pada Formula Nugget Tahu, Ubi Jalar Kuning dan Brokoli. Proporsi taraf perlakuan Nugget ini dengan perbandingan Tahu : Ubi Jalar Kuning : Brokoli adalah P1 (40 : 30 : 30), P2 (50 : 20 : 30), P3 (50 : 30 : 20). Hasil: Penentuan Taraf Perlakuan menunjukkan bahwa nilai terbaik adalah perlakukan 3 (P3) dengan nilai 0,71. Nilai gizi untuk perlakuan 3 (P3) adalah energi 96,50 Kal, protein 3,15 gram, lemak 4,78 gram, karbohidrat 10,38 gram, fosfor 63,38 mg dan vitamin c 4, 53 mg. Hasil organoleptik untuk P3 adalah warna 3,7, aroma 3,75, rasa 3,3, tekstur 3,05. Kesimpulan: Secara organoleptik masing-masing aspek baik warna, aroma, rasa dan tekstur menunjukkan tidak ada perbedaan (nilai p >0,05). Sedangkan komposisi semua nilai gizi terdapat nilai yang berbeda dari masing-masing perlakuan.

 

Kata Kunci: Formula, Nugget, Tahu, Wasting
Sistem Pendukung Keputusan Pemilihan Karyawan Terbaik Menggunakan Metode Weighted Product Pada PT.Steadfast Marine, Pontianak
Authors: Sianipar Deliana , Hendri Hendri
Published: May 2023

The best employees have the potential to increase a company's productivity, which in turn increases profits. However, the problem with PT. Steadfast Marine, a Pontianak-based company that designs and builds ships, has not done the best job of hiring the best employees. Therefore, human resource management, namely using the weighted product (WP) method to select the best employees and improve employee performance in order to remain competitive in the business world, is an important component of successful business operations. Using multiplication to relate the value of the criteria, where each criterion must be raised to the first rank, with the weight of the relevant criteria, taking into account the criteria and weights. To select the best employees accurately and computerized, DSS can help provide solutions. Research was conducted to see and prove the truth and develop pre-existing knowledge by using criteria and applying them to web applications. The employee who was selected as the best employee among the alternatives in the company can be seen from the calculation results. Leading the administration of selecting the best employees. The highest score of 0.0490 as an employee eligible for an award from the company was obtained on behalf of Sau Kong.
Tik Tok in Improving Students' Speaking Skills in the English for Business Course
Authors: Pratama Rizky Mirani Desi , Hastuti Dwi Puji
Published: May 2023

Learning media in the digital era must be aligned with technological developments. The learning media chosen must be interesting and attached to students. The Tik Tok application is currently popular with many people, including the students of administrasi bisnis department, Universitas Bina Sarana Informatika. Departing from these reasons, the researchers took the initiative to implement the Tik Tok application as a medium interesting and fun learning in delivering material in English for Business courses. This study aims to find out how effective the Tik Tok application is in improving the speaking skills of students majoring in business administration at the Universitas Bina Sarana Informatika. Qualitative method is used for analyzing the recorded video on Tik Tok application that were produced by the students as well as processing of questionnaires on student views regarding the use of tick tock media in learning in English for Business courses. The result indicated that the use of the Tik Tok application is considered quite effective in developing students' speaking skills. This can be seen from the results of the recordings sent to lecturers, students are more relaxed and not tense when speaking English using Tik Tok. This was also corroborated by the results of filling out the questionnaire which stated that the Tik Tok application was an innovation in learning English, which made students more relaxed and enjoyed the teaching and learning process and eliminated the mindset that learning English is difficult.
Confinia Psychiatrica: Patient Art and the Diagnosis of Mental Illness
Authors: Duffin Jacalyn , Mikelova Lynda
Published: May 2023

Abstract.

In 1950 in Paris, the inaugural World Conference on Psychiatry hosted an exhibit of artwork by patients, including 150 works from 22 patients of Montreal’s Dr. Ewen Cameron. This event marked the inception of a vigorous but short-lived movement in the history of psychiatry and its relationship to art – not as therapy but as a tool for diagnosis. Two theses elevated the topic to the realm of serious research; their authors became leaders in the field: Robert Volmat (1953) and Irene Jakab (1956).

Identifying roots in the earlier works of Ambroise Tardieu and Hans Prinzhorn and with connections to the Art Brut movement of artist Jean Dubuffet, a group of adherents formed the Société International de la Psychopathologie de l’Expression (SIPE) in Verona, Italy, in 1959. Members sought to release the hidden diagnostic potential of patient art through research on symbols, colour, structure, and content, deriving codes that would point to specific epistemic categories of evolving psychiatric nosology. National societies also arose in many countries. The related journal Confinia Psychiatrica ( Borderland of Psychiatry) ran from 1958 to 1980.

If patient art could be diagnostic, changes in it could be used to assess therapeutic progress. Perhaps for this reason, the pharmaceutical company Sandoz took a particular interest in SIPE, publishing, small collections of patient art of various diagnostic categories and scholarly analysis for distribution to practitioners. We argue that this publishing exercise was a form of corporate advertising – attractive, informative, avant-garde.

This paper traces the history of Confinia and SIPE through the publications and meetings, showing how the attempt to use art for “diagnosis” evolved into the more durable process of art as therapy.
La défense de l’environnement : les mobilisations de la société civile. Introduction
Authors: Larrère Catherine , Schmid Lucile
Published: May 2023

Depuis les années 1970 et la globalisation des questions environnementales, celles-ci sont abordées dans une perspective descendante : des organisations internationales (ONU) aux autorités régionales (Union européenne) et aux gouvernements nationaux, des politiques publiques sont censées appliquer les accords internationaux. Par des lois, des règlements ou des incitations économiques, elles encadrent l’action des entreprises et des particuliers pour réorienter leurs comportements vers des modèles de production et de consommation et plus généralement vers des modes de vie moins destructeurs de notre environnement. Envisagées de la sorte, les politiques écologiques se révèlent plutôt impuissantes. Faut-il en imputer la responsabilité à une société civile récalcitrante à changer ses façons d’être et de faire ? Ce serait ignorer toutes les initiatives citoyennes qui se multiplient, issues d’une société civile qui, bien loin de résister à la transition, se mobilise pour pousser les États à respecter leurs engagements de transformation des modèles économiques et sociaux, et multiplie les façons de faire et les modes de vie alternatifs. C’est sur ces mobilisations que ce numéro de The Tocqueville Review/La Revue Tocqueville a engagé l’enquête.
Stereolithography in Medical Device Fabrication
Authors: Skoog S.A. , Narayan R. J.
Published: May 2023

The development of biocompatible resins and improvements in stereolithography are driving innovations in drug delivery, biosensing, diagnostic testing, and surgical devices and procedures.
Multilayer Thermal Barrier Coatings for Gasified Coal Based Turbine Engines
Authors: Dwivedi Gopal , Viswanathan Vaishak , Sampath Sanjay
Published: May 2023

This article discusses some of the newer thermal barrier coating materials being considered for use in gasified coal-based turbines and how they compare with conventional materials in terms of bond coat oxidation and topcoat damage due to particle erosion and molten ash deposits.
Thermal Spray Materials and Coatings for Sustainable Energy Resources
Authors: Nestler Montia C. , Sharma Atin , Höhle Hans-Michael
Published: May 2023

Thermal spray technology is increasingly being used in alternative energy applications such as solid-oxide fuel cells, solar panels, and wind and hydropower turbines.
Selective-Melt Sintering Brings Speed and Efficiency to Creating High-Density Ceramics
Authors: Narayan J.
Published: May 2023

Selective-melt sintering is faster and more efficient than the methods currently used to make high-density ceramics. This article explains how applied electric fields contribute to the formation of metallic precipitates at grain boundaries and how defect segregation and field-assisted migration generate heat near dislocations and in grain boundaries, reducing flow stress and retarding grain growth in the solid state.
Reducing the Impact of Bird Strikes
Authors: Perumal Ganthimathinathan
Published: May 2023

Simulating bird-plane collisions helps aviation engineers design safer aerostructures and reduce physical testing.
Robotic Testing and Characterization Making Headway
Authors: Kaifler Robert
Published: May 2023

Several industries are now expanding robot integration beyond production tasks into new areas such as testing, where it has been shown to increase throughput and eliminate operator influence.
Renewed Interest in Triboglide Due to Its Excellent Wear and Friction Properties
Authors: Dixit Satish
Published: May 2023

Renewed interest in a NASA-developed material known as Triboglide has led to a study of the friction and wear properties of HVOF-sprayed Triboglide coatings and close variants. This article describes the coating process, examines coating cross-sections, and presents and analyzes the results of high-temperature pin-on-disc wear tests.
Opportunities for Thermal Spray in Functional Materials, Electronics, and Sensors
Authors: Sampath Sanjay
Published: May 2023

Thermal spraying is being incorporated into more manufacturing processes where its primary role is to deposit a layer of material or a free-standing structure that has a functional, rather than a passive, role. Examples include thermally sprayed membranes, electrodes, antennas, thermocouples, inductors, and electrical contacts.
Does Dietitian Involvement During Pregnancy Improve Birth Outcomes? A Systematic Review
Authors: Hanifi Madeha , Liu Wenjun , Twynstra Jasna , Seabrook Jamie A.
Published: May 2023

Maternal diet during pregnancy can have a significant impact on maternal and offspring health. As nutrition counselling is an important component of prenatal care, registered dietitians (RDs) are uniquely trained professionals who can provide personalized nutrition counselling customized to an individual’s sociocultural needs. The objective of this systematic review was to determine if RD involvement during pregnancy is associated with a lower prevalence of adverse birth outcomes in the United States and Canada. The review was conducted through a search of four databases: PubMed, CINAHL, Embase, and Web of Science. A total of 14 studies were identified. Women had a lower prevalence of low birth weight and preterm infants when RDs were involved during prenatal care. While RD involvement during pregnancy was not associated with macrosomia, more research is needed to assess its relationship with small for gestational age, large for gestational age, and infant mortality. Future research should also investigate the specific dietary advice provided by RDs and the extent and timing of their involvement throughout pregnancy to better understand the mechanisms surrounding nutrition counselling, in utero development, and health outcomes.
Teaching Chemistry by Means of Modern Research
Authors: Bobizoda G.M.
Published: May 2023

Education is currently undergoing "deep" modernisation. In accordance with this, the main outcomes of educational institutions are not the knowledge itself, but a set of social competences in the most important spheres of life. Learners should adopt a set of socio-political, intellectual, informational and civic competences when they enter "adult life". The teaching of different sciences in educational institutions contributes to the formation of diverse concepts and the development of critical thinking among learners. An important point in the understanding of knowledge should include pupils’ acceptance of personal relevance, which leads to an understanding of chemistry as a science in the context of global challenges to humanity. The development of a chemical picture of the world among learners is important for the formation of a scientific outlook and a culture of ecological thinking and behaviour. That’s why, the scientific picture of the world would be fundamental for the development of nanotechnology in the educational process.
Promoting continuous pedagogical education in the Republic of Kazakhstan
Authors: Zhaitapova A.A.
Published: May 2023

The article examines the conceptual foundations of continuous pedagogical education and its promotion in the Republic of Kazakhstan. The authors analyze the organization and management of continuing education, consider the design of a model of continuing pedagogical education, which includes a wide range of issues from the definition of the conceptual content, structure and stages of its functioning to the mechanisms of its implementation. The theoretical and methodological foundations of teacher training in the system of continuing professional education are determined based on the analysis of many sources, including normative legal acts and scientific and methodological literature. The approaches and principles implemented in continuing education, which is a single, holistic and integrated process, are disclosed. The main components of this process are three types of educational activity — formal, informal and informational, designated in modern theory and practice as an "educational triad". The authors present a component-competence model of a teacher in the system of continuing education with the definition of the levels of professional components of activity and, accordingly, the development, at the moment of the study, of the general competencies of teachers. The relevance of this article is due to the results of studying the demand for professionally educated and qualified specialists in modern society, a social order aimed at acquiring competitive competencies by them. The authors thank the Ministry of Education and Science of the Republic of Kazakhstan for the organization and grant support of the project scientific research under the coordination of the National Academy of Education named after Ybray Altynsarin for the development of the system of continuing pedagogical education in the context of Life-Long Learning.
Phycological bases of Development of cognitive, action, emotional reflection of students
Authors: Toktanova A.K.
Published: May 2023

The study considers the psychological aspects of the development of language reflection of the individual. The relevance of the article is the study of the current state of reflection, the study of the student's inner feelings and thoughts, emotional state, the specifics of their actions, thereby developing the student's reflection, based on the scientific views of psychologists of different centuries. The novelty of the research is to determine the need for the student not only to understand himself, but also to take into account the actions and cognitive concepts of the external environment, to recall actions, to develop consciousness, cognition, thinking, to determine the impact of correct thinking on future plans. The author expresses his scientific views and fresh ideas, based on the scientific concepts of domestic and foreign scientists. The methods of induction, deduction, generalization, analogy, modeling were used in the study. As a result of the research, the author proposed a new model for the development of cognitive and intellectual reflection of young people in the country, based on the concept of the famous scientist Shchedrovitsky to study the situation, identify difficulties in action, identify the causes of difficulties, self-criticism. In addition, based on the views of domestic and foreign scientists, a model for the development of cognitive reflection of the student was proposed, taking into account the development of the ability to think through comprehension and attention.
The need to form “hard skills” and “soft skills” for future pedagogues in the context of digitalization of education
Authors:   Karagandy University of the name of academician E.A. Buketov, Kazakhstan, Shkutina L.A. , Iskhakbayeva T.G. ,   Karagandy University of the name of academician E.A. Buketov, Kazakhstan, Karmanova Zh.A. ,   Karagandy University of the name of academician E.A. Buketov, Kazakhstan, Danek Jan ,   Saint Cyril and Methodius University, Trnava,
Published: May 2023

The article is devoted to the actual problem of the organization of personal development of future pedagogues in the process of their professional training. As a solution to this problem, the authors pay attention to the study of the problem of the formation of hard skills and soft skills in future pedagogues, their role in professional career and personal development. These skills allow future pedagogues to success adaptation to the educational environment. The role of the formation of hard skills and soft skills in the process of professional development of future pedagogues in the context of digitalization of education is increasing every year. The article discusses the concepts of hard skills and soft skills and their importance for the development of future pedagogues in the professional field. The authors conducted a literary analysis on the topic of the study, noted common and distinctive features in approaches to the understanding of supra-professional and professional skills by various authors. The authors conducted a survey among students of the educational program 6B01101 — Pedagogy and psychology, the basis of the study was the pedagogical faculty of the Karaganda University of the name of academician E.A. Buketov. The results of the empirical research conducted by the authors are presented in the article. The results of the study allowed the authors to conclude that it is necessary to form not only theoretical knowledge, but also practical skills that will contribute to the creation and development of a competitive and competent society of pedagogues of a new formation. The problems raised by the authors are relevant for further research and will be continued in the search for forms and methods of forming hard skills and soft skills for future pedagogues in the conditions of digitalization of education.
MEDAN MAKNA PERALATAN RUMAH TANGGA TRADISIONAL DALAM BAHASA DAYAK BELANGIN (KAJIAN SEMANTIK)
Authors: Novita Grasela , Lahir Muhammad , Ramaniyar Eti
Published: May 2023

Penelitian ini bertujuan untuk mendeskripsikan medan makna peralatan rumah tangga tradisional dalam Bahasa Dayak Belangin di Kecamatan Air Besar Kabupaten Landak. Metode dalam penelitian ini menggunakan metode deskriptif dan bentuk penelitian kualitatif. Sumber data dalam penelitian adalah bahasa yang dituturkan oleh masyarakat dayak Belangin. Teknik pengumpul data yang peneliti gunakan yaitu, teknik simak libat cakap dan teknik wawancara. Hasil penelitian ditemukan, pertama komponen makna pada bahasa Dayak Belangin ada yang terbuat dari anyaman, kayu, besi, tembaga, batu, rajutan benang, tanah liat, dan  bambu. Kedua, jenis makna dalam medan makna peralatan rumah tangga tradisional dalam Bahasa Dayak Belangin yang peneliti temukan yaitu, makna leksikal dan makna kolokatif (lingkungan dapur, lingkungan halaman, lingkungan ruang tamu, lingkungan kamar, lingkungan sungai, lingkungan kolong rumah), dan ketiga, peran semantis berperan sebagai tempat untuk menyimpan bawang, berperan sebagai pegangan parang, ketam, berperan sebagai landasan untuk memotong daging, berperan sebagai memukul pasak, berperan memarut kelapa, berperan sebagai tempat duduk, berperan untuk memotong dan membelah kayu, berperan untuk menebang pohon.Kata Kunci: Medan Makna, peralatan rumah tangga tradisional, bahasa dayak Belangin
ANALISIS KAUSALITAS KONFLIK TOKOH UTAMA DALAM NOVEL API TAUHID KARYA HABIBURRAHMAN EL SHIRAZY (KAJIAN PSIKOLOGI SASTRA)
Authors: Juniarti Meiga Tri , Lahir Muhammad , Hartati Mesterianti
Published: May 2023

Penelitian ini bertujuan untuk mendeskripsikan kausalitas yang terdapat dalam konflik internal dan eksternal yang dialami tokoh utama dalam novel Api Tauhid karya Habiburrahman El Shirazy. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif. Berdasarkan analisis data, dapat disimpulkan bahwa dalam novel Api Tauhid karya Habiburrahman El Shirazy terdapat konflik internal dan konflik eksternal yang dialami oleh tokoh utama. Wujud konflik internal yang dianalisis kausalitasnya yaitu berupa rasa sedih, ragu, malu, bingung, kaget, dan kecewa. Sedangkan wujud konflik eksternal yang dianalisis kausalitasnya yaitu pada saat musim salju yang membuat Fahmi kedinginan, adanya perdebatan antara Fahmi dan Ali, terjadinya penculikan terhadap Fahmi dan Aysel yang dilakukan oleh orang asing, dan terjadinya penyiksaan yang dilakukan Carlos terhadap Fahmi. Selain itu penelitian ini juga dapat dimanfaatkan sebagai bahan ajar dalam pembelajaran bahasa Indonesia pada materi unsur-unsur intrinsik dalam karya sastra berbentuk novel. Kata kunci: Kausalitas, Konflik, Tokoh Utama, Novel
ANALISIS TINDAK TUTUR DIREKTIF DALAM NOVEL ORANG-ORANG BIASA KARYA ANDREA HIRATA (KAJIAN PRAGMATIK)
Authors: Mardian Sari , Sulastriana Elva , Uli Indriyana
Published: May 2023

Tujuan penelitian ini untuk mendeskripsikan tindak tutur direktif dalam novel Orang-Orang Biasa karya Andrea Hirata. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan bentuk kualitatif. Teknik pengumpulan data menggunakan teknik studi dokumenter. Data dalam penelitian ini adalah kata, frasa, dan kalimat yang mengandung tindak tutur direktif dalam novel Orang-Orang Biasa karya Andrea Hirata. Sumber data dalam penelitian ini adalah novel Orang-Orang Biasa Karya Andrea Hirata. Teknik pemeriksaan keabsahan data menggunakan triangulasi teori. Teknik analisis data menggunakan teknik analisis konten. Hasil penelitian ditemukan (1) Bentuk tindak tutur direktif perintah, permintaan, ajakan, nasihat, kritikan, dan larangan. Fungsi tindak tutur direktif memerintah, menyuruh, menginstruksikan, menyilakan, memaksa, mengharuskan, meminta, memohon, menawar,  mengusulkan, menantang, mengajak, mengimbau, menasihati, menyarankan, menyerukan, mengingatkan, memarahi, menyindir, mengumpat, melarang, dan mencegah; (2) Konteks penggunaan tindak tutur direktif berupa konteks fisik dan konteks sosial; (3) Strategi penggunaan tindak tutur direktif berupa tindak tutur langsung dan kesantunan positif.Kata kunci: pragmatik, tindak tutur, tindak tutur direktif, novel.