bluuebunny/crossref_metadata_2025 huggingface dataset:
Enzymes in the Content of Combined Antimicrobials as Improvers of Their Action
Authors: Stepanov N. A. , Aslanli A. G. , Domnin M. V. , Efremenko E. N.
Published: September 2024

Accumulating information about the growing number of microorganisms that are resistant to the antibiotics used, on the one hand, and the emergence of information about the presence of laboratories in which closed work is carried out with microbial pathogens, the negative properties of which can be artificially enhanced.

The aim of the work to analyze current trends in the development of antimicrobial drugs combining the use of wellknown and widely used antibiotics, as well as substances with antimicrobial properties, including metal nanoparticles, antimicrobial peptides, with various enzymes that allow to preserve and enhance the antimicrobial effect against the cells of various microorganisms

The source base of the research is mainly English–language scientific literature available via the global Internet network, as well as the authors’ own published experimental studies.

The research method is analytical.

Results. The work considers enzymes that, unlike classical antimicrobial agents, which more often enter into reactions inhibiting key biochemical reactions, are catalysts for processes aimed at oxidation and hydrolysis of molecules that are metabolically and structurally important for microorganisms.

Conclusion. The enzyme repeatedly enters into reactions that significantly reduce the concentrations of substances important for the vital activity of microbial cells, which leads to their weakening and more effective action of antimicrobial agents. Most often, in this case, the enzymes themselves act as carriers for molecules with antimicrobial action, which avoids their non-specific interaction with other, primarily proteins, thus removing some, for example, antibiotics, from the active effect on pathogen cells. It has been demonstrated that the enzymatic enhancement of the bactericidal action of antimicrobial agents can be in relation to different cells, including the complex biosystems (biofilms) formed by them, both by several times and by several orders of magnitude. Such antimicrobial agents combined with enzymes may be of interest for carrying out sanitary treatments of various surfaces, containers, premises, including biological laboratories, for the introduction of protective and dressing materials.
Modern Hardware and Software Solutions for Whole-Genome Sequencing, Prospects of Their Implementation in the Practice of Nuclear, Chemical and Biological Protection Troops of the Armed Forces of the Russian Federation
Authors: Petrov A. A. , Kazantsev A. V. , Kovalchuk E. A. , Pavlyukov M. Yu. , Sapkulov A. V. , Kutaev D. A. , Borisevich S. V.
Published: September 2024

One of the promising areas for improving laboratory diagnostics is the active introduction of next-generation sequencing (NGS), which retains the key advantages of molecular tests and allows the detection of a wide range of diverse microorganisms. Despite the significant advantages of NGS in the laboratory diagnosis of infectious diseases, there are also a number of objective obstacles to its widespread use.

The purpose of the work is to consider existing hardware and software solutions for whole-genome sequencing, as well as the prospects and problems of their implementation in the practice of the RCB protection troops of the Armed Forces of the Russian Federation for the identification of pathogens of various etiologies.

The source base of the research includes an analysis of data published in domestic and English-language scientific publications, as well as posted on the Internet.

The research method is analytical.

Results. Materials are presented that summarize data on three generations of sequencing technologies, their advantages and disadvantages. It is shown that with the development of NGS technologies, many technical problems arise that need to be deeply analyzed and solved. Despite its great potential, NGS has not yet been widely adopted in clinical microbiology laboratories, partly due to the lack of standardized workflows.

Conclusions. For the successful use of NGS by units of the RCB protection troops of the Armed Forces of the Russian Federation, it is necessary to solve the main problem, which is the development of domestic hardware, appropriate bioinformatics tools and databases certified in accordance with the established procedure for functioning offiine without connecting to the Internet.
Greek Fire, Poison Arrows, and Scorpion Bombs Biological and Chemical Warfare in the Ancient World
Authors: Supotnitskiy M. V.
Published: September 2024

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Development of the program of complex standardization of the closed-loop economy
Authors: Antonov S. A. , Gorbashko E. A.
Published: September 2024

Aim. Provision and development of standardization on the basis of system approach, improvement of perspective planning of standardization at all stages of product life cycle and intersectoral interaction using the program of complex standardization, leading and stepped standards.

Objectives. To analyze the current regulatory acts of the Russian Federation (RF); to determine the main approaches to the implementation of closed-loop economy based on standardization, taking into account the available experience of program activities in the field of standardization.

Methods. The methodological basis of the study is the paradigm of the closed-loop economy. This paradigm embodies a comprehensive approach to the formation of the closed-loop economy standardization program by classifying the goals of creating a system of standardization of the closed-loop economy.

Results. According to the results of the analysis of regulatory legal acts of the Russian Federation and fundamental standards of the national standardization system, the “tree of objectives” is formed, the basis of which is “the formation of a program of integrated standardization of all subsystems of the closed-loop economy”. It is proposed to use the possibilities of advanced standardization in planning the development of standards included in the comprehensive standardization program. The algorithm for the development of the system of complex standardization programs that solves the issues of inter-sectoral interaction is presented.

Conclusions. The system analysis of normative-legal acts of the Russian Federation and fundamental standards of the national standardization system allowed to find ways of linking subsystems of the closed-loop economy, providing a full cycle of circularity and use of material resources from their manufacture to secondary application.
A model of regional distribution of labor migrant numbers
Authors: Trapitsin S. Yu. , Fedorov P. M.
Published: September 2024

Aim. To develop a model of regional distribution of the number of labor migrants that estimates determinant regional disparities factors.

Objectives. To study theoretical approaches to the study of regional distribution of the number of labor migrants; to analyze the factors of regional disproportions of the Russian labor market in modeling migration flows; to collect and analyze statistical information to develop a model of regional distribution of the number of labor migrants that assesses determinant regional disproportions factors.

Methods. General scientific methods of research such as deduction, analysis, synthesis were used. Statistical methods of data analysis were applied, linear regression model was built.

Results. The stable trends of natural population decline, population aging, leading to an outstripping reduction in the number of able-bodied population of the Russian Federation (RF), indicate the need for replacement migration. Regional differentiation in the labor market, characteristic of the Russian economy, can be balanced by both internal migration and external migration flows. However, effective replacement migration is associated with the presence of certain conditions and also carries risks. Such conditions include economic attractiveness of the Russian labor market for foreign workers, integration potential of the host community (absence of anti-migrant attitudes or discriminatory practices). At the same time, replacement migration carries the risks of negative changes in the structure of the labor force due to the relatively low qualifications of migrant workers, weakening incentives to innovate and maintaining a low level of labor productivity, transfer of money received by migrants as wages outside the Russian Federation.

Conclusions. As a result of the regression analysis, the position about the determinant role of regional differentiation of income distribution of the population in determining the regional distribution of the number of labor migrants was confirmed. The regression model uses the indicator of the share of labor migrants in the employed population as the dependent variable characterizing the intensity of labor migration to the region, and data on the average per capita monetary income of the population in the regions of the Russian Federation as the independent variable. The calculation of the regression coefficient indicates the presence of a weak correlation between these variables. Thus, regional disparities in the level of income affect the formation of imbalance in the placement of foreign labor force, since it is the economic factor of attractiveness of the regional labor market that forms the flows of labor migration in the regions.
Developing a taxonomy of decisions based on artificial intelligence technologies in health care practices
Authors: Lapidus L. V. , Tokareva O. M.
Published: September 2024

Aim. To conduct an analysis of research on the application of artificial intelligence (AI) technologies in medicine, norms and practices governing this field, and on its basis to build a taxonomy of AI-based decisions in the practice of medical services.

Objectives. To structure existing AI-based solutions in medicine; to identify, based on research and state registration data, the most mature areas of AI application and potential areas of development; to study the specific features of the applied technologies.

Methods. The authors using general methods of scientific cognition in various aspects considered the sphere of application of AI technologies in medicine, identified and systematized the characteristic features of the current state of this field and trends of further development.

Results. According to the results of the analysis of existing solutions in the field of AI application in medicine all solutions are divided by the degree of elaboration, main processes and type of used data. The constructed taxonomy is the first step in comprehending and structuring the existing AI solutions, possibilities of their use in the process of rendering various medical services.

Conclusions. Today, the most developed area of AI use in medicine is the analysis of medical images in the process of diagnosis, treatment and rehabilitation. Further development and introduction of these technologies into medical practice requires a more structured approach to assessing their effectiveness and efficiency, as well as solving a number of ethical and regulatory issues.
Specific features of labor payments according to competences of the personnel of mass working specialties
Authors: Batsokin A. O. , Khoroshiltseva N. A.
Published: September 2024

Aim. To substantiate the expediency of the competence approach in the labor remuneration of the personnel of mass working specialties, as well as to consider specific features of the practical implementation of labor remuneration of this category of personnel regarding the order of formation of material remuneration by competences and the structure of competence assessment elements.

Objectives. To define the role and essence of supraprofessional competences in labor remuneration; to analyze the structure of wages in the aspect of establishing the elements of material remuneration formed by competences; to form approaches to the assessment of competences taking into account the specifics of the personnel of mass working specialties.

Methods. In order to establish the part of wages formed by competences, the authors have carried out a comparative analysis of modern labor remuneration systems. The procedure for assessing the competences of the personnel of mass work specialties is based on the approach used by the federal centers of competence assessment.

Results. Methodological proposals for the improvement of the labor remuneration system for the personnel of mass working specialties are formed, which consist in the allocation of a variable part as a material remuneration based on the results of competence assessment. The assessment of competences is considered as a single complex tool, including the assessment of professional and supraprofessional competences.

Conclusions. Recommendations of the authors of the article on improvement of the system of labor remuneration of the personnel of mass working specialties on the basis of the competence approach will allow to provide growth of labor productivity, formation of long-term competitive advantages, increase the level of adaptability of workers to changes in the production environment.
Transformation of the Russian market of digital financial assets at the present stage
Authors: Emirov N. D. , Makarov M. Yu.
Published: September 2024

Aim. To study the transformation of the digital financial assets (DFA) market in the Russian Federation (RF) at the present stage.

Objectives. To disclose the essence and role in the economy of DFA; to analyze the volume of the DFA market and their numbers for 2023; to consider the types and advantages of DFA; to identify the main prerequisites for the introduction of the digital ruble in the financial system of the Russian Federation; to study the process of introduction of central bank digital currencies (CBDCs) in different countries; to show new opportunities and prospects for making payments and storing funds using the digital ruble.

Methods. The authors used a comprehensive approach combining general scientific methods, methods of comparative and economic analysis, analytical processing and graphical presentation of information.

Results. The trend of DFA development as a specific type of economic assets is considered. Emphasis is placed on the study of the transformation of the Russian DFA market at the present stage. The participants of the DFA market are described, their role in its functioning is revealed. The graphical analysis of the DFA market volume and their number for 2023 is carried out. The impact of the introduction of the digital ruble on the transmission mechanism of monetary policy is studied. The factors of financial stability under the conditions of the introduction of the digital ruble have been analyzed.

Conclusions. At present, the financial and banking spheres are leading in the introduction of blockchain into their systems, as they are experiencing the process of digitalization to the greatest extent. The accelerating growth rate of the number of issued DFAs for 2023 that we have identified indicates an increasing interest in the new digital financial instrument by issuers. It was found that in the process of transformation of the Russian DFA market all prerequisites for the introduction of the digital ruble have been formed, which, acting as an additional monetary unit, can successfully counteract the problems of the financial sector. The introduction of the digital ruble has a complex and multifaceted effect on the transmission mechanism of monetary policy. It requires careful analysis and a strategic approach on the part of regulators in order to maximize the positive impact on the economy and minimize possible risks and negative consequences. In the long term, under the conditions of financial sanctions imposed on the Russian Federation, the digital ruble can become an effective alternative to traditional international settlements.
Structure of household income as a factor of financial development of municipalities
Authors: Pasynkov A. F.
Published: September 2024

Aim. To determine the Russian specifics and interrelations in the structure of sources of income of Russian households and living standards of the population on the example of municipal formations of a number of regions of the Russian Federation (RF).

Objectives. To consider the domestic and foreign experience of singling out the interrelations of socio-economic development of territories and the structure of household income; to develop a methodology for assessing and forming a statistical base for assessing the structure of house-hold income; to calculate the interrelations of the structure of household income (labor, entre-preneurial income, social payments) and the standard of living of the population in the municipal formations of the Ural Federal District (UFD).

Methods. As a source of information we used publicly available databases on municipal entities of Rosstat, which present household incomes and social payments to the population. On this basis, adjustments and necessary calculations were made regarding the sources of household income and the formation of the database of average per capita income in municipalities of the UFD regions.

Results. The share of social payments in the total income of households in the municipalities of the UFD regions was calculated. In urban areas the share of social payments is close to the average Russian value, while in rural areas the share varies by regions. The correlation between labor and entrepreneurial incomes was determined; the southern regions of the district show an approximate parity of labor and entrepreneurial incomes of households, while in the northern municipalities three quarters of incomes fall on labor activity. As a result, the interrelationships of rural and urban settlements’ income structure with average per capita incomes are highlighted. The factors influencing this correlation for each type of municipal formations in the UFD regions were identified.

Conclusions. The study has shown that in general in the UFD municipalities the most significant component of income is the income from wage labor and social payments. In the southern regions of the UFD large cities have a great influence on the studied indicators, in the northern regions — natural resource extraction activities. Thus, the factors of financial development in the context of personal income are very diverse and depend on many conditions. The main ones include urbanization of the territory, availability of minerals, settlement system (large regional centers).
Impact of international sanctions pressure on the activities of higher education institutions of the Russian Federation
Authors: Panasenko N. V.
Published: September 2024

Aim. To identify the degree of influence of events related to the imposition of external sanctions on the functioning of higher education institutions in the Russian Federation (RF) and to make their structuring depending on the nature and scale of the imposed sanctions.

Objectives. To consider the main problems arising before higher education institutions in connection with the increasing number of imposed sanctions against the RF; to analyze their impact on the risks of educational institutions; to identify methods of their reduction; to assess the level of their variability in modern conditions.

Methods. In the process of the research the general scientific methods of cognition, system and comparative analysis of statistical information, scientific systematization and generalization of normative-legal documentation were used.

Results. The general characterization of the negative effect of the introduction of international sanctions on the country’s economy in general and on the sphere of higher education in particular is given. The impact of sanctions on the work of institutions of higher education system of the Russian Federation in the aspect of development of international cooperation in the field of science and education has been assessed. The sources of new types of risks are identified and the level of threats from their realization is justified, the most effective methods of management of these types of risks in modern geopolitical conditions are characterized.

Conclusions. It is established that the introduction of international sanctions had a significant impact on the system of higher education in Russia, the dynamics of their introduction revealed the depth of contradictions between the systems of social order of the Russian Federation and the countries of the global West. The negative factors of the impact of the imposed sanctions on the activities of Russian educational institutions have been assessed. At the same time, the sanctions pressure in general and exclusion from the Bologna system in particular led to the mobilization of internal resources, showed the need for reforms in education and science, contributing to the strengthening of scientific sovereignty of the country. With this Aim. The Government of the Russian Federation together with the Ministry of Science and Higher Education of the Russian Federation is implementing a set of measures aimed at supporting and ensuring the progressive development of domestic science and education. The analysis of changing risk factors and methods of their minimization has shown that in the conditions of changing norms and rules of international relations the need to find new ways to neutralize threats is undeniable.
Directions of activation of investment processes in tourism industry
Authors: Tarakanov A. V.
Published: September 2024

Aim. To identify the problems and prospects of tourism investment activity in the conditions of a complex geopolitical situation at the present stage.

Objectives. To define the role of the tourism industry development; to group the targets set for achievement as a result of investment programs implementation; to describe the current state of investment processes in the tourism industry; to identify the most frequently arising problems and to form proposals for their overcoming.

Methods. The author used general scientific methods, including analysis and synthesis, description, as well as methods of structural, system and economic analysis.

Results. The development of the tourism sector is included in the main tasks of integrated sustainable development of the region. In order to activate private investment in the tourism industry, the state program of the Russian Federation (RF) “Tourism Development” has been developed, which specifies the algorithm for achieving the strategic objectives contained in the Strategy of Tourism Development in the Russian Federation for the period up to 2035. The main condition is the creation of an attractive investment environment to ensure the reduction of the payback period of projects and leveling of entrepreneurial risks, an environment that promotes the increase in financing of creative projects for the development of supportive infrastructure. Despite the set tasks and allocated funds, the contribution of the tourism industry to the gross domestic product of the Russian Federation is not significant. The size of public and private investments in the tourism industry does not allow us to talk about the possibility to fully disclose the tourist potential of our country. The article reveals the problems of tourism industry development, offers a typology of legal models of investment projects taking into account their comparative characteristics.

Conclusions. In the conditions of the new geopolitical order outbound tourism along classical directions is practically absent. However, Russia has a huge potential for the creation of powerful tourist zones for domestic tourism. A new tourist map of world tourism is being formed, and it is necessary to form organizational, economic, legal mechanisms for the application of effective investment tourism practices.
ФОРСИТЬ VS ФОРСИРОВАТЬ: GRAMMATICAL ADAPTATION OF THE LATEST VERB BORROWINGS FROM THE ENGLISH LANGUAGE
Authors: KONONOVA Irina
Published: September 2024

The relevance of the research is due to its focus on the analysis of the latest verb borrowings, reflecting modern processes in the language. The novelty of the work is determined by the identification of factors influencing the choice of verb suffixes, which serve for the grammatical adaptation of modern English borrowings to the Russian language system. During the research, morphemic and morphonological analysis methods were used.
The work highlights the tasks of grammatical adaptation of borrowings that determine the choice of a suffix: 1) the complete preservation of the sound shell of the prototype from the source language; 2) compliance with the law of consistency, that is, compliance with the linguistic system of the acceptor language; 3) compliance with the law of economy.
It is concluded that the choice between the most frequent suffixes for grammatical adaptation of the latest verb borrowings from the English language is determined by different types of conjugation corresponding to these suffixes and, accordingly, different types of morphonological transformations. When using the suffix -и-, alternations occur at the junction of the root and the suffix or at the junction of the stem and the ending; as a result, the principle of preservation of the sound shell of the prototype from the source language is violated. When using the suffix -а- interfixation occurs at the junction of the stem and ending; as a result, the sound shell of the prototype from the source language is preserved, but the linguistic law of economy is violated.
VARIATON IN EXPRESSION AMONG GRAMMARIANS
Authors: Al-Zubaidi Ahmed
Published: September 2024

This research paper reminds those in charge of the Arabic languag development and those who teach it of what Arabic has devolved into, as a hybrid language that dominated their tongues, being broken in their mouths, and its aesthetics distorted. The study looked into the eloquent expression that was among the first generation of grammarians such as Al-Khalil bin Ahmed, Sibaweih, Al-Akhfash Al-Awsat, Al-Farra’ and Al-Mubarrad, who had elevated Arabic to what has reached us from them. While it was damaged by others, whose expression had dried up and became devoid of eloquence, their speech was afflicted by aridity and logic, and there was no eloquent expression in it. Among these grammarians are Tha'lab, Al-Zajjaj, Al-Serafi, Abu Ali Al-Farsi, and Al-Rrmmani. This research paper warned this generation, along with the efforts made among the dedicated people to Arabic in our modern era. The paper called for the preparation of the teacher of Arabic in a way commensurate with its characteristics and aesthetics and for several parties to rise and unite for this great task and save this generation from the harm caused by all means of communication: visual, audio and written.
FACTORS THAT PUT THE UZBEK TURKİSH LANGUAGE OF AFGHANİSTAN AT RİSK OF LANGUAGE DEATH
Authors: AKBARİ Najibullah
Published: September 2024

The extinction of any language is an irreparable loss for humanity. According to some sources, only 600 of 6000 languages are safe. Many specialists in the field provide important decisions to prevent the extinction of the languages. According to linguists, at least half of the languages in the world will die at the end of the 21st century. The study attemts to reveal the past and present dangers facing the Uzbek Turkish of Afghanistan with universal and regional factors.
CUMMAN WORDS IN CODEX CUMANICUS AND AFGHANISTAN KYPCHAK TURKISH
Authors: AKBARİ Najibullah
Published: September 2024

Codex Cumanicus is a two-part work compiled in the 14th century by Italians and Germans from the Kypchak (Kuman) Turks in the north of the Black Sea. Perhaps it is the only compact heirloom of the Kypchak Turkish accent. In this manuscript, known as Codex Cumanicus in scientific circles, collective information on the language of Cuman Turks is given. Codex Cumanicus, which is an extremely important source in terms of Turkish dialect research, contains a dictionary of Kypchak (Kuman) Turkish, which is the common agreement and trade language of various Turkish tribes living in the north of the Black Sea and some nations speaking different languages, and important religious texts belonging to Christianity. Codex Cumanicus is a very valuable work for both the contemporary Kychak group and all Turkish dialects, both because of its vocabulary and because the work's alphabet reflects the period's language better than the Arabic language.Various studies have been carried out on the similarities and parallels between the Kypchak Turkish vocabulary of Codex Cumanicus and some contemporary Turkish dialects in the Kypchak group. However, in this article, the words that are common in the Codex Cumanicus and Afghanistan Kypchak Turkish are investigated.
APHORISM AS A SUBJECT OF LINGUISTIC RESEARCH
Authors: POPOVA Ekaterina
Published: September 2024

The present article deals with the problem of aphorism as an object of linguistic analysis. The article also considers aphorisms as a means of expression reflecting people's wisdom and public opinion. The authors analyse the semantic saturation of aphorisms, their artistic and scientific aspects, as well as their instructive and original character. The aim of the work is to study the peculiarities of the functioning of aphorisms, their varieties and classification, as well as to identify the differences between aphorisms and other types of statements, such as universal sayings, winged expressions, proverbs, phraseological phrases and epigrams. The focus is on identifying the main characteristics of aphorisms, their role in language and culture, and different approaches to classifying the genre. The article is an overview of modern research on the problem of aphorism, as well as a stimulus for further study of this genre in linguistics and cultural studies. The results of the study allow to better understand the nature of aphorism as a unique genre and highlight its peculiarities among other forms of short statements. This article brings a new perspective on aphorisms and their role in language and culture, offering an in-depth analysis and comparison with other related forms of statements
“FIVE COLOURED PENCILS” TECHNIQUE AS A SELF- AND PEER-ASSESSMENT TOOL
Authors: BEGMATOVA Kholida
Published: September 2024

Instructional rubric plays an essential role in the learning process of writing as it might be used not only for the marking process by teachers but also by students in developing writing skills in the classroom. As some university students tend to experience challenges when starting to write and feel anxious about the writing tasks, they usually come unprepared for the feedback sessions. This paper reports on the results of a study that aimed to explore first-year university students’ use of rubrics to self-assess and peer-assess their writing with the help of the Five Coloured Pencils technique. The students at Westminster International University in Tashkent (WIUT) self-assessed and peer-assessed a reflection essay in the classroom. Two groups, one control (n=23) and one treatment (n=23) group, were involved in checking the effectiveness of the coloured technique used in formative assessment sessions. The control group had the conventional approach during the university's feedback sessions. The treatment group has been taught how to self- and peer-assess their work using the instructional rubrics and the Five Coloured Pencils technique to promote their understanding of the instructional rubric. This paper will describe the Five Coloured Pencils technique, the pilot test results on the quality of the essays, and students' satisfaction with the technique. The recommendations for using the Five Coloured Pencils technique for self- and peer-assessment in EFL classes will be presented at the end of the report.
THE CONCEPTUAL USE OF ANIMAL METAPHORS IN THE REPRESENTATION OF HUMANS IN ENGLISH AND UZBEK PROVERBS
Authors: NORMURADOVA Gulnora
Published: September 2024

Proverbs hold significant cultural value as succinct expressions of collective wisdom, reflecting the attitudes, beliefs, and values of a society. Embedded within these short, memorable sayings are insights into cultural norms, social hierarchies, and the human condition. Proverbs serve as a window into the cultural psyche, offering glimpses into societal perceptions of morality, gender roles, and interpersonal relationships. Animal metaphors are a common feature of proverbs across cultures, serving as powerful symbolic representations of human qualities, behaviors, and characteristics. Animals embody a rich array of cultural meanings and associations, making them potent vehicles for conveying complex ideas and cultural values. In proverbs, animal metaphors are employed to illustrate virtues, vices, and universal truths about human nature, providing vivid imagery that resonates with audiences. The purpose of this article is to undertake a comparative analysis of the conceptual use of animal metaphors in English and Uzbek proverbs to represent humans. By examining the underlying conceptual frameworks and cognitive associations embedded within these metaphors, this study aims to elucidate how animal imagery is employed to convey cultural perceptions of human behavior, identity, and social dynamics. Through this analysis, we seek to deepen our understanding of the cultural significance of animal metaphors in proverbs and their role in shaping cultural attitudes and beliefs about humanity.
COMPARATIVE EVALUATION OF HORIZONTAL CONDYLAR
GUIDANCE OBTAINED BY CONE BEAM COMPUTER TOMOGRAPHY AND DIFFERENT INTEROCCLUSAL RECORDING MATERIALS IN DENTATE PATIENTS : AN IN – VIVO STUDY
Authors: Monika Monika , Dahiya Manisha , Arora Aman , Upadhyaya Viram , Dahiya Manisha
Published: September 2024

Aim: The aim of the study was to compare and evaluate the horizontal condylar guidance in dentate patients by CBCT
and different interocclusal materials. In Vivo Comparative study. Settings And Design: Materials And Methods -
Twelve individuals with dentition who were between the ages of 20 and 40 were chosen, and they did not exhibit any symptoms or indications of
temporomandibular joint abnormalities. Protrusive records were made for three different materials with the use of a specially designed protrusive
guide.With the help of semi adjustable hanau H2 articulator horizontal condylar inclination (HCI) value were programmed using these records,
and CBCT was performed. The results were statistically examined. One Way ANOVA/Krsuskal Wallis tes Statistical Analysis Used: t followed
by post Hoc Analysis depending upon the normality of the data. The Shapiro–Wilk test was used to investigate the distribution of the data and
Levene's test to explore the homogeneity of the variables. Among each pair of groups there exists a Results: signicant difference, i.e., the mean
condylar guidance was found to be statistically signicant difference between aluwax , PVS and bisacrylate .No signicant difference was
observed between CBCT and bisacylate. The values of horizontal condylar inclination varied accordin Conclusion: g to the kind of material used.
The study concluded that the horizontal condylar guidance obtained by bisacrylate was statistically similar to CBCT. So, according to results
clinically recommended interocclusal recording material is bisacrylate (Luxabite).
COMPARATIVE ANALYSIS OF SAFETY, EFFICACY AND FETOMATERNAL OUTCOME OF CERVICAL PRIMING WITH MIFEPRISTONE VERSUS INTRACERVICAL DINOPROSTONE GEL
Authors: Khan Shazia , Sharma Pooja
Published: September 2024

Aim: The aim of this study was to evaluate the efcacy and safety of mifepristone for cervical ripening and induction of
labor and compare the results with dinoprostone gel which is an established agent for labor induction. A total of Methods:
200 patients were enrolled in a prospective study and 100 each were assigned to either Mifepristone (M) Group and Dinoprostone (D) group.
Outcomewas evaluated using the improvement in Bishop score(BS) , admission delivery interval, duration between induction and the onset of
active phase of labor , mode of delivery and maternal and fatal outcomes. Though not statistically s Results: ignicant a single dose of 200mg
Mifepristone resulted in better BS at 48hrs post application. The M group required lesser doses of Dinoprostone gel for labour induction and had
lesser LSCS rates. The Apgar scores at 1 and 5 mins were signicantlybetter in M group. The results Conclusion: of the study suggest that oral
administration of 200 mg mifepristone in term patients is more efcacious than Dinoprostone gel for cervical priming by achieving a better BS at
48 hrs.There is a signicant reduction in application to delivery time and a signicant reduction in LSCS rates.
CENTRAL ODONTOGENIC FIBROMA: A CASE REPORT WITH IMMUNOHISTOCHEMICAL ANALYSIS
Authors: Saigal Chhavi , Shruti Shruti , Huidrom Dinabati , Juneja Saurabh , Khare Ankita
Published: September 2024

Odontogenic broma (OF) is a rare odontogenic tumor with a variable incidence that the World Health Organization
(WHO) denes as a benign odontogenic neoplasm that arises from mesenchymal odontogenic tissue, comprising less than
5% of all the odontogenic tumors. It has been reported in patients aged 11 to 80 years old, with a mean age of 34 years and shows no gender
predilection. It presents a diagnostic dilemma because its clinical and radiological features resemble other odontogenic and/or non-odontogenic
tumours, and the differential diagnosis is based on histological examination. In this report, a 65 years old male patient is presented, who was
diagnosed with central odontogenic broma of simple type from clinical and histopathological ndings.
A COMPARATIVE STUDY OF TOPICAL 20% KOH VS. INTRALESIONAL MMR VACCINE IN TREATMENT OF MOLLUSCUM CONTAGIOSUM
Authors: Patel Ravindra , N. Vora Deval , M. Sumana
Published: September 2024

Background: Molluscum Contagiosum (MC) has no FDA-approved treatments as of yet. Although many other
treatments have been suggested, the majority of the efcacy evidence comes from modest case studies. Objectives: The
aim of the current work was to evaluate the safety as well as efcacy of intralesional MMR vaccine immunotherapy versus topical KOH (20 %) in
the treatment of MC. A total of 100 patients (71females and 29 males) with multiple lesions of MC. Patients And Methods: They were divided
into two equal groups at random; group 1 treated by MMR vaccine at 3weeks intervals with a maximum of 3 injections or clinical cure. Group 2
subjected to topical 20% KOH once daily for maximum ten weeks. Complete clinical response was attai Results: ned in 80% of MC patients who
treated with MMR vaccine versus 86% of patients who treated with topical 20% KOH for 10 weeks, while 20 % of patients showed no response
in group 1 versus 4% in group 2 after the end of therapy. without recurrence after 3 months in all patients demonstrating complete reaction. In
group 1, most patients tolerated the side effects, which in 5% of cases manifested as erythema and hyperpigmentation. While in group 2,
hypopigmentation (10%), hyperpigmentation (14%), pruritus (8%) during treatment were reported. There was signicant reported burning
sensation among 25% of patients treated with topical potassium hydroxide (P = 0.047). It could be c Conclusion: oncluded that both topically
applied KOH 20% and intralesional MMR vaccine are dependable, less expensive treatments for non-genital MC.
AMOR E TRANSITORIEDADE NA POÉTICA DO AUDAZ NAVEGANTE: ANÁLISE DO CONTO DE GUIMARÃES ROSA
Authors: Fim Luciana Carvalho dos Reis
Published: September 2024

O estudo em questão realiza uma análise detalhada do conto "A partida do audaz navegante", de Guimarães Rosa, explorando a tradição oral como eixo central para entender a construção narrativa e a interação entre os diferentes níveis de discurso presentes na obra. A pesquisa foi motivada pela necessidade de aprofundar o entendimento sobre como Guimarães Rosa utiliza a tradição oral para construir uma narrativa rica em significados, que transcende o tempo e o espaço, estabelecendo uma conexão profunda entre o narrador, a personagem Brejeirinha e os leitores. O principal objetivo da pesquisa é demonstrar como o autor e a personagem Brejeirinha, ambos narradores da história, utilizam o entre-lugar — um espaço híbrido entre a ficção e a realidade — para desenvolver uma narrativa que reflete um elo de amor, manifestado tanto no enredo quanto nas interações entre os personagens. Nesse sentido, o conto não apenas apresenta uma trama envolvente, mas também revela uma metanarrativa que expõe as camadas de interpretação possíveis através da tradição oral, onde a realidade é constantemente reinterpretada pelos personagens. A metodologia adotada para alcançar esses objetivos incluiu uma análise literária minuciosa do texto, com enfoque na desconstrução dos elementos narrativos e nas interações entre as personagens principais: Brejeirinha, Ciganinha e Zito. Essa abordagem permitiu uma compreensão mais ampla de como os personagens se entrelaçam para compor "a pontinha da realidade", um conceito que indica a linha tênue entre o real e o imaginário no universo rosiano. Os resultados da pesquisa evidenciam a complexidade do entre-lugar na obra de Guimarães Rosa, onde a tradição oral não apenas narra eventos, mas também cria e recria sentidos, reforçando o vínculo emocional entre as histórias e seus narradores.  A conclusão do estudo reafirma a importância da tradição oral como um recurso literário fundamental para a construção de narrativas que ecoam a profundidade das experiências humanas.
Foreste e ciclo dell'acqua: la pompa biotica
Authors: Bottacci Alessandro
Published: September 2024

l presente è un articolo di review sul rapporto tra le foreste e il ciclo dell’acqua, con particolare riguardo al processo indicato come “pompa biotica”. Il Pianeta sta assistendo ad un cambiamento globale senza precedenti. Si registra un forte aumento della temperatura ed una diminuzione della disponibilità di acqua dolce.La deforestazione influisce negativamente sul ciclo dell’acqua, modificando il processo naturale di trasporto a grande distanza dell’aria umida dall’oceano alle aree interne dei continenti. Questo processo, scoperto solo da pochi anni, è stato denominato pompa biotica, ed è attivato proprio dalle foreste, specialmente da quelle naturali. Vengono analizzati i meccanismi di funzionamento di questo processo, la relazione con le foreste naturali e gli effetti negativi della sua alterazione.
ANALISIS FAKTOR PENYEBAB KECELAKAAN LALU LINTAS PADA KURIR EKSPEDISI X DI KECAMATAN BOJONG KABUPATEN TEGAL
Authors: Subekti Agung Tyas , Maulana Muhammad Adhi , Pratiwi Anggit , Sukmandari Erna Agustin
Published: September 2024

Industri transportasi memegang peranan yang sangat krusial dalam meningkatkan kesejahteraan masyarakat. Kemajuan dalam ilmu pengetahuan dan teknologi memungkinkan pembuatan alat transportasi lebih efisien, yang mengakselerasi pertumbuhan jumlah kendaraan secara signifikan. Namun, perkembangan ini juga berdampak negatif, seperti peningkatan kemacetan lalu lintas dan tingkat kecelakaan yang meningkat. Menurut Global Status Report on Road Safety (WHO, 2015), 50 juta orang menderita luka parah akibat kecelakaan lalu lintas di seluruh dunia setiap tahunnya, menewaskan lebih dari 1,25 juta orang. Menurut Korlantas Polri dan dipublikasikan oleh Kementerian Perhubungan pada tahun 2021, tercatat sebanyak 103.645 insiden kecelakaan lalu lintas di Indonesia. Dari keseluruhan jumlah korban kecelakaan di jalan, sekitar 73 persennya terlibat dalam insiden yang melibatkan sepeda motor. Lokasi yang digunakan dalam penelitian ini yaitu Kecamatan Bojong Kabupaten Tegal dan penelitian dilakukan pada bulan Mei-Juni 2023. Subjek penelitian merupakan seluruh kurir yang terdaftar di kantor ekspedisi X. Penelitian ini menggunakan teknik sampling non-probabilitas dengan menerapkan desain judgement sampling. Berdasarkan hasil penelitian Analisis Faktor Penyebab Kecelakaan Lalu Lintas Pada Kurir Ekspedisi X di Kecamatan Bojong Kabupaten Tegal dapat disimpulkan sebagai berikut : penyebab terjadinya kecelakaan adalah faktor pengemudi, lingkungan jalan, kondisi kendaraan, membawa barang berlebih, cuaca dan pengendar lain. Cara mencegah kecelakaan lalu lintas adalah menerapkan safety riding, memperhatikan kondisi cuaca, barang bawaan, kondisi kendaraan, kondisi tubuh, selalu fokus saat berkendara, mematuhi peraturan lalu lintas, memperhatikan kecepatan, dan selalu berdoa.
HUBUNGAN ANTARA BEBAN KERJA DENGAN KELELAHAN KERJA PADA PEKERJA KONSTRUKSI PROYEK KERETA CEPAT JAKARTA BANDUNG DI PT. WASAKA TOMO ENGINEERING
Authors: Nugrahantari Adharia
Published: September 2024

Adanya indikasi bahwa pekerja lapangan di PT. Wasaka Tomo Engineering mengalami kelebihan jam kerja, sehingga berpotensi terjadinya kelelahan kerja yang nantinya beresiko terjadinya kecelakaan kerja. Kemudian penulis mengaitkan penyebab dari kelelahan kerja dengan beban kerja. Adapun tujuan umum dari penelitian ini adalah mengetahui hubungan antara beban kerja dengan kelelahan kerja pada pekerja konstruksi proyek kereta cepat Jakarta Bandung di PT. Wasaka Tomo Engineering, serta tujuan khusus dari penelitian ini adalah mengetahui beban kerja dan kelelahan kerja pada pekerja konstruksi proyek kereta cepat Jakarta Bandung di PT. Wasaka Tomo Engineering.  Metode : Penelitian ini menggunakan jenis penelitian kuantitatif yang menghasilkan beberapa temuan yang dapat dicapai dengan menggunakan beberapa prosedur statistic atau cara-cara lain dari kuantifikasi (pengukuran). Sampel penelitian ini yaitu pekerja konstruksi di PT Wassaka Tomo Engineering, peneliti menggunakan total sampling berjumlah 37 orang. Peneliti menggunakan pendekatan Cross sectional. Untuk teknik pengambilan data penelitian ini menggunakan teknik observasi dan teknik quesioner. Uji hipotesis pada penelitian ini adalah menggunakan analisis univariat dan analisis bivariat, analisis yang digunakan untuk menguji hipotesis hubungan/pengaruh antara dua variabel menggunakan fisher exact test. Hasil : Berdasarkan hasil data yang didapat menggunakan uji fisher exact test peneliti mendapatkan nilai ρ sebesar 0,035 (ρ < 0,05), dan terdapat nilai contingency corfficient sebesar 0,653 yang termasuk dalam kekuatan hubungan yang sangat kuat. Kesimpulan : Terdapat hubungan antara beban kerja dengan kelelahan kerja yang didapat dari hasil uji fisher exact test peneliti mendapatkan nilai ρ sebesar 0,035 (ρ < 0,05), dengan nilai contingency corfficient sebesar 0,653 yang menunjukan bahwa kekuatan hubungan yang kuat., dari hasil tersebut dapat disimpulkan bahwa H0 ditolak dan H1 diterima untuk mengambil keputusan hipotesis.
Effect of Amoxicillin Antibiotic on Germination Rate and Active Components of Triticumaestivum L. (Wheat) Seeds
Authors: Ahmed Sundus Hameed , Yousif Alyaa Mouhsen , Mohammed Hashim Kadhim , Hameed Rasha Sattam , Salem Khaled F. M.
Published: September 2024

According to the best germination percentage and its rate of TriticumAestivum L (Wheat) seeds treated with Amoxicillin 50mg/ml gave the highest germination percentage of 100% and the highest germination rate 0.6, also it gave highest scavenging free radicals of DPPH with a mean percentage of 82.07%. The GC-MAS tests for the control model and wheat plant treated with the antibiotic amoxicillin at concentrations of 25 and 50 mg. It was found that only two materials present in the three models under study: such as Phytol and gamma.-Sitosterol.