bluuebunny/crossref_metadata_2025 huggingface dataset:
Results of the research, development and production seminar for drilling and blasting
Authors:   Institute of Mining UB RAS, Gennadii Bersenev , Kutuev Viacheslav ,   Ural Association of Shotfirers (Vzryvniki Urala)
Published: January 2023

The article provides the results of the research, development and production seminar on drilling and blasting in surface and underground mine workings and special blasting. The seminar was organized by the Ural Association of Shotfirers (Vzryvniki Urala) and held on 26 May, 2022 on the territory of the UMMC Museum Complex in the town of Verkhnyaya Pyshma, with the participation of the Institute of Mining UB RAS and the Ural Department of Rostekhnadzor. Reports on the following topics were presented: special blasting in explosive welding of metals and explosive demolition; experience with nonexplosive mixtures and devices, including pulsed gas generators, in dense urban areas; the outcome of developing and testing the procedure of studying rock mass strength properties in the course of blasthole roller drilling in open pits; forthcoming innovations in Federal Law no. 116 on Industrial Safety of hazardous production sites; relevance, features and conditions of blasting under safety shelters; mining conditions for underground mining at the Donskay Mining and Processing Plant in Kazakhstan. The theoretical part of the seminar was followed by a tour of the exhibition centers of the UMMC Museum Complex including military and automotive museums, the “Wings of Victory” aviation exhibition, the “Ceremonial Regiment” exhibition centre, and an open exposition site with railway and artillery equipment.
Using Flashcards to Increase Grammar Mastery of MTs Students in Kutai Kartanegara
Authors: Armadi Samsu
Published: January 2023

This study reports the difference of using flashcards and textbooks in teaching grammar for junior school students.  The study aimed at examining the hypothesis that read: “flashcards do not improve grammar mastery.” This study used an experimental of post-test only design, implementing an experimental group that received flashcards for the treatments of learning grammar, and the controlled group that received textbooks for learning grammar.  The hypothesis testing at p=0.05 and n = 48 indicated that Ho was rejected and the result was significant (t-value = 3.377 and t- table = 1.68).  This means flashcards significantly improved  grammar mastery.  In other words, flashcards as media of teaching grammar is superior than using textbook.
Psychological stress and cardiovascular diseases: clinical case
Authors: Ebzeeva E. Yu. , Ostroumova O. D. , Mironova E. V. , Doldo N. M.
Published: January 2023

In the modern world, stress occupies a leading place among significant problems for humanity, being an etiological factor of about 80% of diseases. Social, physical and psychological factors can act as stressors that influence and determine the non-specific response of the body. In most cases, the nonspecific stress-induced reaction of the body is manifested by the picture of psychovegetative syndrome, an important component of which is the activation of the sympathetic nervous system. In a prolonged stress situation, psychovegetative syndrome can be a manifestation of stress-induced anxiety. Anxiety is detected in more than 25% of patients with a general somatic profile. Stress-induced reactions and anxiety can subsequently contribute to the development of psychogenic somatic pathology, including the cardiovascular pathology. Acute or chronic stress situation increases the risks of developing arterial hypertension, coronary heart disease, heart rhythm disorders. In the presence of background cardiac pathology, stress-induced reactions contribute to the deterioration of its course and reduce the effectiveness of treatment. The above indicates the need for a comprehensive assessment of the condition of patients with a general somatic profile. The active use in practical medicine of psychometric and psychodiagnostic scales for anxiety and depression is shown to assess the mental status of patients. When detecting stress-induced reactions or comorbid psychopathology, inclusion of psychotropic drugs, including antipsychotics (alimemazine), is indicated in the complex therapy. Timely administration of alimemazine in patients with a general somatic profile stops psychovegetative manifestations, has positive somatotropic effects due to the multimodal mechanism of action of the drug. In this clinical case, the use of alimemazine in a patient with hypertension, rhythm disorders and comorbid anxiety is presented.
Mechanisms of action of rebamipide in the treatment of chronic erosive gastritis patients with type 1 diabetes mellitus
Authors: Pavlenko O. A. , Trynchenkova N. N. , Vorojcova I. N. , Oleynik O. A. , Samoilova Iu. G. , Kharakhulakh M. I.
Published: January 2023

Introduction. Type 1 diabetes mellitus (DM-1) and its complications pose a serious medical and social problem. Erosive changes in the gastric mucosa are among the most common lesions of the digestive system in diabetes mellitus, and can lead to life-threatening gastrointestinal bleeding and early disability of patients.

Aim. Substantiation of the effectiveness of rebamipid course treatment based on an assessment of the functional state and antioxidant activity of the supraepithelial gastric mucosa in chronic erosive gastritis in patients with DM-1.

Materials and methods. A comprehensive examination of 12 DM-1 patients with erosive gastritis and 11 healthy individuals was carried out, including FGDS with biopsy of the antrum mucosa and stomach body, exclusion of Helicobacter pylori infection, determination of the biochemical composition of structural glycoproteins of mucus and the concentration of degraded glycoproteins, evaluation of the antiradical activity of the supraepithelial mucous layer of the stomach.

Results and discussion. In chronic erosive gastritis in patients with DM-1, a significant predominance of degraded monosaccharides in the supraepithelial mucous layer of the stomach was revealed (6 times higher than in healthy individuals), a decrease in the concentration of polymerized glycoproteins in gastric mucus (21% vs. 80%) and a significant increase in the antiradical activity of mucus. Course  treatment of chronic erosive gastritis in patients with type 1 diabetes with rebamipid at a dose      of 100 mg 3 times a day for 3 weeks contributes to the normalization of the indicators of glycoproteins of native mucus, antiradical activity of the mucosa and complete epithelization of the erosions of the antrum of the stomach.

Conclusions. The use of rebamipid in the treatment of chronic erosive gastritis in patients with type 1 diabetes contributes to reducing the degradation of polymerized glycoproteins of native mucus, normalizing the antiradical activity of the mucosa and complete epithelization of erosions of the antrum of the stomach.
Fixed combinations of hypoglycemic drugs in the treatment of patients with type 2 diabetes
Authors: Verbovoy A. F. , Verbovaya N. I. , Dolgikh Yu. A.
Published: January 2023

The prevalence of diabetes mellitus (DM) in our country is quite high. Most of them are type 2 diabetes. This pathology is characterized by a rather high disability and mortality. The main cause of deaths in type 2 diabetes are cardiovascular diseases – about 52.0%. An important reason for the development and progression of these complications is the lack of compensation for diabetes, which is currently a serious problem. Thus, according to statistics in Russia, the proportion of compensated patients with type 2 diabetes with a glycated hemoglobin level of less than 7.0% is only slightly more than half of all patients. The reasons for insufficient compensation of the disease may be such factors as the lack of patient education and self-control, as well as the patient’s low adherence to compliance with the rules for taking hypoglycemic drugs. The use of prolonged forms of drugs, as well as combined drugs, increases the adherence of patients to therapy. Among oral medications for the treatment of type 2 diabetes, the most commonly prescribed drugs are metformin and sulfonylurea (SM) derivatives. The joint appointment of these groups of drugs improves glycemic control of patients. There are drugs containing fixed combinations of metformin and SM derivatives. For example, containing 2.5 mg/tab of glibenclamide and 400 mg/tab of metformin, and 2.5 mg/tab of glib-enclamide and 500 mg/tab of metformin and 5 mg/tab of glibenclamide and 500 mg/tab of metformin, as well, containing 2 mg/tab of glimepiride and 500 mg/tab metformin. Such dosages are convenient for patient intake and further titration, also have a low risk of hypoglycemia.
Possibilities and prospects for antioxidant therapy in ocular diseases
Authors: Prikhodko V. A. , Okovityi S. V.
Published: January 2023

The eye is particularly vulnerable to oxidative stress due to its constant exposure to atmospheric oxygen, sunlight, ultraviolet and ionizing radiation, chemicals, pollutants, and microorganisms that may shift the physiological balance towards oxidation. Today, oxidative stress is considered a major pathogenetic feature of a wide spectrum of ocular conditions including diseases of the lens (cataract), anterior chamber (glaucoma), cornea (keratoconus, traumatic injuries, post-operative conditions), eye surface (pterygium, dry eye syndrome), retina (uveitis, retinopathies), and optic nerve (optic neuropathies, glaucoma). Potential strategies for pathogenetic therapy in conditions, associated with oxidative stress, include direct inhibition of lipid peroxidation, induction of Nrf2 transcription factor signaling, repression and sequestration of vascular endothelial growth factor (VEGF), and the use of agents with direct antioxidant effect. Methylethylpyridinol or 3-oxy-6-methyl-2-ethylpyridine hydrochloride, a potent free radical scavenger, is often regarded as a major antioxidant agent for ophthalmological purposes. Methylethylpyridinol is characterized by a possibility of being used in different types of dosage forms. In ophthalmology, it is given by injection, as well as by instillation in the form of eye drops. Methylethylpyridinol can be used for the treatment and prevention of inflammation and burn injuries of the cornea, hemorrhages into the anterior chamber of the eye and into the sclera, thrombosis of the central retinal vein and its branches, diabetic retinopathy and complications in myopia, as well as for the protection of the cornea when exposed to high intensity light and wearing contact lenses. This paper reviews the main features of oxidative stress as the leading pathogenetic factor in ocular diseases, and the possibilities of antioxidant therapy using methylethylpyridinol.
Hospital readmissions of patients with COVID-19: causes, features, outcomes
Authors: Potanina O. N. , Ayrapetyan S. A. , Mazurenko S. O. , Strizheletsky V. V. , Palchikova L. S. , Teplyakova N. A. , Ermolaeva L. G. , Gomon Iu. M. , Semigolovskii N. Yu.
Published: January 2023

Introduction. On average, 10% of patients hospitalized due to new coronavirus infection (COVID-19) will be readmitted. To date, the reasons for readmission and the characteristics of these cases are not fully presented.

The aim of the study was to analyze readmissions of COVID-19 patients to identify the causes of readmission, clinical features, examination data and treatment outcomes.

Materials and methods. The study was performed retrospectively by using electronic records of the medical cases of the St. Petersburg City Hospital of St. George. Inclusion criteria: 1) the presence of two or more hospitalizations during 2020–2021; 2) COVID-19 confirmed by polymerase chain reaction within 14 days before or during the first hospitalization, or the detection of changes in the lungs with a high probability associated with COVID-19 during primary computed tomography. One hundred and two people met the specified criteria.

Results. In 85% of cases, the cause of re-admission was symptoms of respiratory infection; in 13% – thrombotic events (pulmonary embolism, acute cerebrovascular accident, deep vein thrombosis of the lower extremities); 12% – severe pain syndrome of various localizations; 11% - infectious and inflammatory processes; 9% – antibiotic-associated diarrhea; 5% – atrial fibrillation and less often other pathologies. Patients with respiratory symptoms had a high degree of respiratory failure, an increase in the volume of affected lung tissue and an increase in the content of various markers of inflammation in the blood when compared with the data of the initial examination. Nine percent of patients died during hospitalization.

Conclusions. The leading cause of repeated inpatient treatment of COVID-19 patients were symptoms of reactivation of the infection with a number of indicators of a greater severity of this “second wave” of the disease. Further studies are required to reduce the risk of repeated inpatient treatment.
РАЗВИТИЕ СОЦИАЛЬНО-МЕДИЦИНСКОЙ ПРАКТИКИ ТРЕПАНАЦИИ ЧЕРЕПА
Authors: Филипских Д.А. , Чуйков О.Е.
Published: January 2023

В статье предпринята попытка провести изучение происхождения трепанации черепа как первого оперативного способа врачевания болезней центральной нервной системы.
Assessment of water resources system resilience under hazardous events using system dynamic approach and artificial neural networks
Authors: Stojković Milan , Marjanović Dusan , Rakić Dragan , Ivetić Damjan , Simić Višnja , Milivojević Nikola , Trajković Slaviša
Published: January 2023

The objective of this research is to propose a novel framework for assessing the consequences of hazardous events on a water resources system using dynamic resilience. Two types of hazardous events were considered: a severe flood event and an earthquake. Given that one or both hazards have occurred and considering the intensity of those events, the main characteristics of flood dynamic resilience were evaluated. The framework utilizes an artificial neural network (ANN) to estimate dynamic resilience. The ANN was trained using a large, generated dataset that included a wide range of situations, from relatively mild hazards to severe ones. A case study was performed on the Pirot water system (Serbia). Dynamic resilience was derived from the developed system dynamics model alongside the hazardous models implemented. The most extreme hazard combination results in the robustness of 0.04, indicating a combination of an earthquake with a significant magnitude and a flood hydrograph with a low frequency of occurrence. In the case of moderate hazards, the system robustness has a median value of 0.2 and a rapidity median value of 162 h. The ANN's efficacy was quantified using the average relative error metric which equals 2.14% and 1.77% for robustness and rapidity, respectively.
Early warning index of flash flood disaster: a case study of Shuyuan watershed in Qufu City
Authors: Teng Xiaomin , Zhang Xiaoxiao , Jiao Jiamin , Diao Mengyao , Li Wanglin
Published: January 2023

Flash flood disaster is one of the important natural disasters, bringing harm to human life and causing serious economic losses, so it is urgent to improve the accuracy of flash flood warning. To determine the critical rainfall and early warning indicators of disaster prevention objects, the Shuyuan Watershed of Qufu City Shandong Province was selected as the research object, the key disaster prevention objects were screened and finally, Hengmiao Village and Gaolou Village were selected as typical disaster prevention objects. Empirical analysis method, Storm analysis method, and model analysis method were used to calculate the critical rainfall at different times under different soil water content conditions, compare and analyze the rationality and existing problems of these three methods, and comprehensively determine the indicators of typical disaster prevention objects under different circumstances. The results show that the value of the index calculated by the storm analysis method is small and calculated by the model analysis method is large. This paper can improve the accuracy of flash flood warning, select the critical rainfall calculation method according to local conditions, accurately calculate the parameter values, and deal with the problem of effective early warning in the region as a whole.
An Update on the Recent Green Synthetic Approaches for Imidazo[1,2-a] Pyridine: A
Privileged Scaffold
Authors: Bhatt Keval , Patel Dhara , Rathod Mrudangsinh , Patel Ashish , Shah Drashti
Published: January 2023

Imidazo[1,2-a]pyridine is a fused bicyclic heterocycle that is known as a "drug prejudice" scaffold because of its numerous uses in organic and medicinal chemistry for the development of new drugs. As an outcome, numerous techniques for synthesizing this important class of compounds have been established. Some methods, however, are associated with toxic and corrosive catalysts, longer reaction times, poor yields, lower purity, and by-products in addition to the desired product. Green synthetic methods, which include microwave-assisted synthesis, catalyst-free, solvent-free, green solvent-based synthesis, mechanochemistry, and many others, are used to reduce the usage and production of harmful organic substances. These techniques improve reaction efficiency compared to conventional ones and also reduce the utilization and production of hazardous chemicals. Due to the implication of the imidazo[1,2-a]pyridine backbone as a biologically active ubiquitous fragment and the current demands of reducing toxic solvents, catalysts, and energy consumption, this review focuses on providing comprehensive highlights of the recent green synthetic pathways for imidazo[1,2-a]pyridine.
Multi-target Polypharmacology of 4-aminoquinoline Compounds against
Malaria, Tuberculosis and Cancer
Authors: Nandi Sisir , Chauhan Bhumika , Tarannum Heena , Khede Mayank Kumar
Published: January 2023

Background:

Polypharmacology means drugs having interactions with multiple targets of a unique disease or many disease pathways. This concept has been greatly appreciated against complex diseases, such as oncology, CNS disorders, and anti-infectives.

Methods:

The integration of diverse compounds available on public databases initiates polypharma-cological drug discovery research. Immunocompromised patients may suffer from complex diseas-es. Multiple-component drug formulations may produce side effects and resistance issues due to un-intended drug-target interactions.

Results:

Polypharmacology remains a novel avenue to propose a more effective and less toxic treatment. The 4-amino quinoline scaffold has become an important construction motif for the de-velopment of new drugs against lifestyle diseases like cancer and infectious diseases like tuberculo-sis and malaria.

Conclusion:

The present study is an attempt to explore the polypharmacological effects of 4-aminoquinoline drugs to combat malaria, cancer, and tuberculosis.
Fibrolipomatous Hamartoma of the Median Nerve: A Clinical Report of One Case and Review of the Literature
Authors: Xing Guojing , Shang Xiaojie , Huo Xiaoguang , Han Shiliang , Wang Yanzhen , Xu Wenzhe
Published: January 2023

Background:

The ultrasound imaging findings and clinical treatment procedure of a case of fibrolipomatous hamartoma of the median nerve are reported in this paper. The disease diagnosis was mainly dependent on magnetic resonance, and rarely described by ultrasound. This paper introduces the imaging manifestations of median neurofibromatoid hamartoma under ultrasound.

Case Presentation:

This case is a middle-aged female with pituitary adenoma. Fibrolipomatous hamartoma, as a rare benign fibrofatty tumor, is characterized by the slow proliferation of mature adipocytes and fibrous tissue around and inside the peripheral nerves, eventually leading to the fusiform enlargement of nerve fiber bundles.

Disscussion:

This paper discusses the value and application of color doppler ultrasound in the diagnosis of FLH to provide a reference for the clinical diagnosis and treatment of this disease in the future and reviews the literature on this disease.

Conclusion:

Because fibrolipomatous hamartoma is very rare, it is very important to improve the understanding and diagnosis of this disease.
Assessment of Circulating CCR6 Level in Acute Myocardial Infarction
and its Association with Disease Severity
Authors: Abdelrahman Amira Mohamed Noureldin , Mohamed Amal Elmahdy , Bendary Ahmed Mahmoud , Sedki Amira Adel , El-Shimi Ola Samir
Published: January 2023

Background:

Background: Acute myocardial infarction (AMI) pathophysiology is mediated by systemic, intraplaque myocardial inflammatory processes that occur mainly due to coronary artery thrombosis in an atherosclerotic plaque area. The G-protein-coupled chemokine receptor (Ccr6) is displayed on the surface of many types of leukocytes, that have been found in atherosclerotic plaques. It is a novel mediator of inflammation and immune response.

Objectives:

To determine CCR6 lymphocyte expression in AMI patients and its association with disease severity using the Gensini scoring system.

Methods:

25 AMI patients and 25 controls underwent flow cytometry to determine the percentage of circulating CCR6+ lymphocytes. To forecast AMI and determine how CCR6 expression relates to it, multivariate logistic regression analysis was used.

Results and Discussion:

There was a higher percentage of CCR6+ lymphocyte expression in AMI patients than in controls. In addition, CCR6 showed a significant positive correlation with the Gensini score (GS) in the AMI group then with the degree of coronary artery disease (CAD).

Conclusion:

The chemokine receptor Ccr6 is an independent biomarker for AMI and mayplay a role as a mediator of T lymphocyte recruitment, which is associated with coronary lesion destabilization.
Intranasal Delivery of Leuprolide Acetate Chitosan Nanoparticles for
Treatment of Alzheimer’s Disease
Authors: Pandya Tosha , Dharamsi Abhay
Published: January 2023

Background:

Alzheimer’s is one of the primary causes and the most prevalent form of age-related dementia worldwide. There is an urgent surge to find an effective treatment for AD due to its social implications on society.

Aim:

Present research work aims to develop Chitosan nanoparticles of leuprolide acetate for the treatment of Alzheimer’s disease by delivery through the intranasal route.

Methods:

Chitosan nanoparticles encapsulating leuprolide acetate were prepared using the ionic ge-lation method and optimized using a central composite design. The optimized nanoparticles were evaluated by DSC study, TEM analysis, release study of the drug in vitro and ex vivo, histopatholo-gy study, and accelerated stability study, In vivo kinetic and dynamic study.

Results:

The optimized formulation exhibited particle size of 254.3 ± 10.7 nm, % EE of 85.6 ± 0.8
%, and zeta potential of +18.0 ± 0.2 mv. The release of drug from optimized nanoparticles in vitro
was in a sustained manner, with only 75.7 % drug released at 48 hours. Higher permeation of the
drug from nanoparticles (Papp =5.44 ± 0.34 x 104) was observed in the diffusion study ex vivo. Sheep
nasal toxicity and accelerated stability study proved the intranasal safety and stability of the developed
formulation. The in vivo drug uptake study indicated a greater brain drug concentration from
chitosan nanoparticles than from plain drug solution. The anti-Alzheimer potential was also evident
from behavioural studies and histopathology study of rat brain.

Conclusion:

Thus, the chitosan nanoparticulate formulation of leuprolide acetate was found to have great potential for Alzheimer’s disease management.
Ispitivanje znanja romskih žena o reproduktivnom zdravlju u romskoj zajednici grada Rijeke
Authors: Redžepi Ingrid , Bošković Sandra
Published: January 2023

Zdravlje reproduktivnih organa od velike je važnosti u životu svake žene, budući da je sve veća učestalost pojave karcinoma maternice i jajnika i karcinoma dojke, kako u Hrvatskoj tako i u svijetu. Pojavnost bolesti reproduktivnih organa kod romskih žena često je uvjetovana načinom života uzrokovanim smanjenom emancipacijom i zapostavljenošću žene, zbog kulturalnih razlika i zatvorenosti prema okolini. Cilj rada bio je ispitati znanje romskih žena o zdravlju reproduktivnog sustava. Na istraživanje su se odazvale 62 ispitanice romske nacionalne manjine grada Rijeke, u dobi iznad 30 godina života. Istraživanje je provedeno kao presječno, pomoću anonimnog anketnog upitnika, uz suglasnost ispitanica. Rezultati pokazuju da romske žene nisu dovoljno informirane, odnosno da imaju nedostatno znanje o reproduktivnom zdravlju, prevenciji bolesti reproduktivnih organa, važnosti redovitog odlaska ginekologu, važnosti metoda zaštite od spolnih bolesti i kontracepcije. Također, rezultati pokazuju da su mlađe, školovanije i zaposlene ispitanice imale više znanja od starijih ispitanica, onih bez završene škole i nezaposlenih. Rezultati ukazuju na činjenicu da na većinu pitanja koja se smatraju ključnima za reproduktivno zdravlje većina ispitanica ne zna odgovor. Želja za učenjem i povećanjem razine znanja o ovoj temi daje nadu u suradnju za daljnje djelovanje na tom području. S obzirom na rezultate istraživanja, potrebno je poraditi na osviještenosti o prevenciji i zaštiti zdravlja žena romske nacionalne manjine i podizanju samosvijesti i samopoštovanja. Za preporučiti je izraditi plan edukacije ove populacije s ciljem podizanja znanja o reproduktivnom zdravlju.
Subjektivni doživljaj arhivskog istraživanja ratne siročadi iz Drugog svjetskog rata
Authors: Seferović Jelena
Published: January 2023

Članak razmatra emocionalno iskustvo istraživanja osobnih kartona ratne siročadi iz Drugog svjetskog rata – korisnika zagrebačkog sirotišta “Josipovac”. Odluka o odabiru teme razvila se iz potrebe za analizom ranjivosti istraživača koji provode arhivska istraživanja podataka o traumatičnim iskustvima. Konkretan povod za pisanje članka bili su osjećaj nostalgije i tuge koji su se javili kod istraživačice tijekom i nakon čitanja sadržaja iz rubrike “Sjećanja od kuće”, rubrike za koju nije bio predviđen prostor u prijemnim listovima ratne siročadi, nego su je proizvoljno uveli odgajatelji iz “Josipovca”. Zanimljivo je istaknuti kako faktografski podaci iz njihovih biografija, zabilježeni u tim unaprijed definiranim rubrikama, nisu pobudili značajnije emotivne reakcije kod istraživačice, štoviše, gotovo da je bila ravnodušna prema njima. Analizirajući njezina iskustva u kontekstu teorija biblioterapije ustanovilo se da arhivska istraživanja ratne traume mogu kod istraživača koji ih provode izazvati preplavljujuće neugodne osjećaje. U bioetičkoj literaturi često se ističe važnost pokazivanja razumijevanja i suosjećanja prema sudionicima istraživanja koji su proživjeli neki traumatski događaj. Budući da se u istoj rijetko tematizira pitanje empatiziranja s istraživačima koji ih provode, trebalo bi ga detaljnije raspraviti u kontekstu načela bioetičkog senzibiliteta.
Tečajevi/radionice likovne kulture i osobe starije od 50 godina
Authors: Pavlović Eduard , Jovanović Paula , Pešić Vesna
Published: January 2023

Cilj ovoga rada bio je vidjeti koliko određena poimanja o tečajevima/radionicama likovne kulture donekle mogu u osoba starijih od 50 godina potvrditi Lefebvreovu misao: „Mi treba da živimo u svakidašnjici; nju valja preobraziti“. Ovim istraživanjem nasumice su obuhvaćene osobe zatečene na različitim mjestima tijekom listopada i studenog 2021. godine. Za potrebe ovog istraživanja strukturiran je kraći vlastiti upitnik sastavljen od 6 pitanja. Dodatne pribilježbe ukazuju da su anketi pristupile 33 osobe, da je glavnina ispitanika bila u dobi od 51. do 70. godine života (21 ili 63 %), uglavnom rođenih u hrvatskim urbanijim sredinama, intelektualnih odnosno službeničkih zanimanja (17 ili 51 %), podosta umirovljenih (napose muškaraca) te onih s dvoje djece (16 ili 48 %), sa stanom ili kućom u srednjem ili manjem gradu u Hrvatskoj (21 ili 61 %), većinom religioznog svjetonazora (27 ili 82 %). Glede ciljane problematike većina je odgovorila da joj je donekle poznata likovna umjetnost (17 ili 52 %), da ih ona zanima ili donekle zanima, da ih nešto više interesira slikarstvo odnosno kiparstvo/keramika, da im je stručnije znati gledati likovno djelo (20 ili 61 %), da im je stalo i do druženja (25 ili 71 %), ali da im je važna i cijena tečaja/radionice (17 ili 52 %). Za raspraviti je ili umjesto zaključka ustvrditi da i ove pokusne studije ukazuju da osobe starije od 50 godina žele promjene u svojoj svakidašnjici, ali da su im važni i troškovi realizacije takvih preobrazbi.
A Study on the Analysis of the Interrelationship between the Epic of Gilgamesh and the Bible Using Text Mining
Authors: Kang Jinoon , Kim Sujung
Published: January 2023

The development of human civilization is a continuous process of imitation and creation based on exchange. Most historical research is performed qualitatively, so consequently, historical interpretations tend to be biased with personal or subjective viewpoints. In this context, Bible is the most-read book in history and comparative studies are steadily conducted owing to its similarities with the myths of ancient civilizations. This study combines qualitative and quantitative analysis to analyze the interrelationship between a myth and the Bible. Specifically, intertextuality analysis was performed around the great flood episode in Mesopotamia’s Epic of Gilgamesh and the Bible’s Genesis. Text mining–based association rule analysis and word cloud analysis were combined to verify this. Intertextuality analysis revealed the interrelationship between the Epic of Gilgamesh and the Bible; moreover, text mining helped verify the association in intertextuality analysis. Through this, the study proposes a research method for civilization exchange studies by objectively approaching the flow and directionality of exchanges among civilizations in the ancient Mediterranean regions. Furthermore, along with civilization exchange studies, a practical convergent research method for studies in the areas of humanities, regional studies, and history was suggested.
Boletín de indicadores en ciencia tecnología e innovación del sector agropecuario
Authors: Niño Vargas Edna Juliana , González Cerón Sandra Paola , Ramírez Beltrán Angélica María , Moreno Valderrama María Nancy , Uribe Galvis Claudia Patricia
Published: January 2023

El Boletín de indicadores de ciencia, tecnología e innovación del sector agropecuario colombiano hace parte de los instrumentos con los que cuentan los actores del Sistema Nacional de Innovación Agropecuaria (SNIA) para conocer el entorno de la investigación, el desarrollo tecnológico y la innovación a través de información relacionada con: i) el monto de la inversión pública y la ejecución de recursos de distinta naturaleza en actividades de este tipo, ii) la cantidad y el tipo de proyectos vigentes, iii) las capacidades disponibles en términos de talento humano (programas de formación, investigadores, graduados), iv) las relacionadas con infraestructura (laboratorios, bibliotecas, software) y v) otras capacidades como publicaciones, productos y servicios tecnológicos, oferta tecnológica, entre otras.
¿Cómo tener un manejo adecuado del cultivo de tomate?
Authors:   Corporación Colombiana de Investigación Agropecuaria - AGROSAVIA, Dominguez Pulgarin Dominguez-Pulgarin
Published: January 2023

Mantener las condiciones adecuadas de un invernadero es muy importante para la productividad de un cultivo, el investigador de AGROSAVIA Cristian Dominguez, nos da tips para poderlo implementar
The Acceptability of Technology-Based Physical Activity Interventions in Postbariatric Surgery Women: Insights From Qualitative Analysis Using the Unified Theory of Acceptance and Use of Technology 2 Model
Authors: Thérouanne Pierre , Hayotte Meggy , Halgand Florent , d'Arripe-Longueville Fabienne
Published: January 2023

Background

Bariatric surgery offers an opportunity for physical activity (PA) promotion due to patients’ increased ability to engage in PA. Technology-based PA interventions are promising tools for promoting PA to support patients in this key period. The Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model is a recognized theoretical model for examining technology acceptability. Although a previous study reported that 92% of women with obesity have high acceptability of at least one technology-based PA intervention, little is known about the factors that lead to different levels of acceptability between technologies and therefore the reasons for choosing a preferred intervention.

Objective

The purpose of this study was to (1) characterize the acceptability of 3 technology-based PA interventions (ie, telehealth, active video game, mobile app) in the context of bariatric surgery, and (2) explore patients’ preference motives. This study, using a qualitative design, examined the suitability of the UTAUT2 model in this specific context.

Methods

Participants (n=26) read written French descriptions of the technology-based PA interventions with illustrations and chose their preferred intervention. Semidirective interviews were conducted to explore the reasons for their choice of the preferred intervention, notably using the UTAUT2 framework. Data were analyzed based on inductive and deductive approaches.

Results

All participants who preferred a technology-based PA intervention (ie, active video game, n=10; mobile app, n=10; telehealth, n=6) expressed a behavioral intention to use it. In addition, some of them expressed a high behavioral intention to use another technology (ie, active video game, n=4; mobile app, n=1; telehealth, n=7). All the constructs of the UTAUT2 emerged during the qualitative interviews and were specified through subcategories. Additional constructs also emerged, especially other motivational factors.

Conclusions

This study showed that, in the context of technology-based PA interventions for postbariatric patients, the UTAUT2 is suitable, although additional motivational factors (which were not considered by the UTAUT2 model) should be considered.
Educational Effects of and Satisfaction with Mixed-Reality-Based Major Trauma Care Simulator: A Preliminary Evaluation (Preprint)
Authors: Lee Han-Dong , Huh Yo , Kim Sora , Baek Ji-Woong , Lee Hojun , Park Sang-Min , Kim Jin-Kak
Published: January 2023

BACKGROUND

Mixed reality (MR) is a hybrid system that projects virtual elements into reality. MR technology has the advantage of providing immersive learning using various real-world tools. However, studies on educational programs using MR are scarce.

OBJECTIVE

This study aimed to investigate the educational effects of and satisfaction with an MR-based trauma decision-making simulator.

METHODS

A total 40 of trainees self-selected to participate in this experiment. All participants participated in the MR trauma simulator for approximately 30 minutes and conducted voluntary learning without any external help. Declarative knowledge, measured using 20 multiple-choice questions, was assessed before and after MR trauma training. To confirm the educational effect, test scores before and after MR trauma training were compared using a paired t-test. Student satisfaction after training was measured using a ten-item questionnaire rated on a five-point Likert scale.

RESULTS

A pretest-posttest comparison yielded a significant increase in declarative knowledge. The percentage of correct answers to multiple choice questions increased (from a mean of 42.3, SD 12.4 to 54.8, SD 13) after the MR-based trauma assessment and treatment training (P < 0.001). Of the participants, 79.45% were satisfied with the overall experience of using the MR simulator.

CONCLUSIONS

This study demonstrated a meaningful educational effect of the MR-based trauma training system even after a short training time.
Quality and reliability assessment of Youtube on the interpretation of laboratory test results (Preprint)
Authors: ÖZTÜRK EMRE Hümeyra , BERÇİK İNAL Berrin , ÖRNEK DİKER Vesile , DÜZ Muhammed
Published: January 2023

BACKGROUND

YouTube is used to investigate medical conditions, diseases, drug abuse, etc., and may contain inaccurate material.

OBJECTIVE

Our study aims to investigate the effectiveness of YouTube videos in interpreting laboratory results.

METHODS

Two independent biochemists looked for and rated videos through the Global Quality Scale (GQS) and modified DISCERN methodology. The characteristics of the low-, intermediate-, and high-quality groups were compared using the Kruskal- Wallis test. The kappa coefficient measured the researchers' agreement.

RESULTS

Of thirty-five videos, thirteen (46%) were in the high-quality group, eleven (32%) were intermediate-quality, and eleven (32%) were low-quality, as determined by the GQS ratings. The quality groups had similar daily views, likes, dislikes, and comments (p>0.05). However, group DISCERN scores varied greatly (p<0.001).

CONCLUSIONS

Due to YouTube's lack of restrictions, content creators are not required to have a specific area of expertise, which may result in posting potentially confusing videos by persons devoid of knowledge or experience.
Utility of Laplace Transform in Mathematics
Authors: Yadav Dr. Dhiraj
Published: January 2023

The paper seeks to analyze the use of Laplace transform in mathematics. However it contributes in mathematics as well as in arena of physics and engineering also. Laplace transform is an important skill to solve linear ordinary and partial differential equations with constant coefficients under suitable initial and boundary conditions. It is a good technique to simplify complex differential equations to a simpler form having polynomials in the area of stability and control. The current far-reaching use of the transform (mainly in engineering) happened during and soon after 2nd World War ,With the ease of application of Laplace transforms in myriad of scientific applications, many research softwares have made it possible to activate the Laplace transformable equations directly supporting the researchers. The transformation is usually used in stochastic performance modelling and analysis of computer and communication systems. It gets significant applications in various areas of physics, electrical engineering, control engineering, optics, mathematics and signal processing.
Stakeholders Awareness and Acceptability on the VMGO and Grading System of Bohol Island State University-Clarin Campus
Authors: C. Batan Dearyl Mae , N. Bojos Sheila Mae , B. Dinoy Romar , A. Labrigas Menchie
Published: January 2023

A survey was done among 314 respondents from Bohol Island State University (BISU) Clarin Campus. Students, faculty, staff, and parents/guardians answered the survey questionnaire to examine the awareness and acceptability of the BISU vision, mission, goals, objectives, and grading system of the undergraduate and graduate programs. The researchers utilized descriptive survey design with the use of questionnaire as the main tool for data gathering. The study found out that the stakeholders are aware of the university’s vision, mission, goals, as well as of the objectives and grading system of BEEd, BSEd-Mathematics, and MAEd programs. Also, the vision, mission, goals, objectives and grading system were considered to be acceptable to the stakeholders. Hence, a parallel study may be conducted yearly to assess and monitor the stakeholders’ awareness and acceptability of the VMGO and grading system of the different programs that the university offers.
Decoding Crime and Punishment in Colonial India: Analysing Surjatamashi, Nibarsaptak, and Thugee or Thug
Authors: Mukherjee Rajarshi , Dasgupta Koyel
Published: January 2023

Crime has been an intrinsic part of human society since its inception and has eventually shaped itself as a social phenomenon. Crime follows punishment even though not in all cases but both are considered to be intertwined with one another closely and the latter happens as a consequence of the former. Crime is a behaviour that is not socially acceptable and despite the viciousness associated with it, crime is a transgression of the social rules as to how humans need to conduct themselves. The advent of the British as a colonial power introduced India to western thoughts, ideals, and scientific and technological advancements. The dwellers of the Western world came with not solely what was desirable but also that which a healthy human society does not find worth welcoming. Criminal propensities of the human disposition in the Western world were perpetuated into Indian society with their arrival.
Synthesis and Characterization of rGO/Fe3O4 Nanocomposite as Counter Electrode for Dye Sensitized Solar Cell
Authors: Manishankar M. , Ramesh K , Kulandaivel D , Babu M Shoban
Published: January 2023

Abstract: In this project work deals with the synthesis and characterization of rGO/Fe3o4 nanocomposite as counter electrode for dye sensitized solar cell . The growing population in the world arouses energy concerns in all kinds of fields. It is mandatory to meet our everyday energy demands from solar, wind, geothermal, and so on. The proposed Dye-Sensitized Solar Cells (DSSC’s) belong to the group of thin-film solar cells that have been the subject of research for more than two decades due to their low cost, simple preparation methodology, low toxicity, ease of production, and simple methodology. Still, there is a lot of scope for the replacement of current DSSC’s materials due to their high cost, limited abundance, and long-term stability. These cells have the advantages of low-energy and high-throughout processing technologies, low material costs, and the ability to work even in low incident light conditions. To studied about the structural and morphological properties of synthesized rGO/Fe3O4 nanocomposite by using various characterization techniques such as XRD analysis, then the efficiency of existing DSSC’s may be upto 10-12% by using eosin yellow dyes and optimising material.
Air Population Components Estimation in Silk Board Bangalore, India
Authors: Masineni Nikitha
Published: January 2023

Abstract: As we see on global arena most of the political leaders focus us on how to reduce carbon prints and make the planet a safer place to breathe. Though the focus on reducing pollution we hardly have technologies which focusses on reducing pollution, while reducing pollution is one aspect identifying source of pollution is another important aspect. Even though we intent to reduce pollution we still see there is lot of shortcomings. We intend to focus on how pollutants vary over a period of time and if there is any seasonal pattern, We also look forward to vary pollutants to see which pollutants causes variation in particle matter i.e Pm2.5 and Pm10. SARIMA modelling is used which mainly focuses on decomposing the data and giving the residual details. The RMSE is 10.97 which shows the model is efficient enough to predict the pollutants and particulate matter
Reaumuria soongorica-plant model to understand drought adaptive mechanisms of xerophyte and their potentials in improving stress tolerance in plants
Authors:   College of Desert Control Science and Engineering, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, People’s Republic of China, 010 010, Ma Y. M. , Liu R.X. ,   College of Desert Control Science and Engineering, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, People’s Republic of China, 010 010, Wang S.S. ,   College of Desert Control Science and Engineering, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, People’s Republic of China, 010 010, Han F. ,   College of Grassland Resources and Environment,  Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, People’s Republic of China, 010 010
Published: January 2023

Reaumuria soongorica plays critical role in withstanding wind-induced soil erosion and combating desertification due to its unique drought adaptive networks involved in physiological, morphological, biochemical, and molecular biological levels. This review was conceived to summarize the most updated information on drought adaptive mechanisms of R. soongorica to formulate valuable strategies for non-xerophytes crop species to be drought tolerant. Research indicates that R. soongorica can be drought resistant via posing a high root to shoot ratio, having salt secreting gland, subsidized stomata, hard leaf texture, pallet leaf shape, high seeds viability, actively working antioxidative enzymes, secondary metabolites, phytohormones, and differentially expressed drought resistant genes. These characteristics interlink at morpho-physiological, biochemical, metobolic, molecular, and genetic level in R. soongorica to adapt the extreme abitotic stress conditions in desert regions as a plant model in xerophyte. The potentials of using the genetic elements in R. soongorica to produce drought tolerant crop species for yield production on growing on marginal lands could be vital for maintaining future food security. However, functional gene cloning and their transformation in crop species should be conducted as pre-requisite. Key words: Abiotic stress, Crop improvement, Drought adaptive mechanisms, Reaumuria soongorica, Xerophytes
Oximetría de pulso en enfermedades respiratorias
Authors: Bandera-Barros Juan José , Méndez-Hernández Jorge Camilo , Wilches-Visbal Jorge Homero
Published: January 2023

El pulsioxímetro es un dispositivo que utiliza principios de espectrofotometría y fotopletismografía para la medición de la saturación de oxígeno arterial, así como el ciclo cardiaco y respiratorio, lo que resulta útil para monitorear pacientes con compromisorespiratorio. En este trabajo se realiza una revisión bibliográfica de los principios físicos del pulsioxímetro y sus avances más recientes en pacientes con enfermedad pulmonar obstructiva crónica (EPOC), asma y COVID-19. Se encontró que la oximetría de pulso es una herramienta confiable y eficaz en el diagnóstico y la prevención de complicaciones en pacientes con estas enfermedades respiratorias.
Los elementos formativos de la historia: tiempo, mito y generación
Authors: González Martín Francisco Javier
Published: January 2023

Tiempo, mito y generación son solo tres elementos de los muchos que forman la historia en su desarrollo. Se trata de conceptos que hay que tener en cuenta, ya que se utilizan de forma constante; además cabe hablar de sus categorías, en cuanto al tiempo, hay que diferenciar entre cronos, kairos o pléroma. En el caso del mito, entender la creencia no como algo imaginario, sino como un componente psicológico interno de personas y colectivos. La generación es un tema biológico y cronológico, algo que determina el cambio de mentalidad. Todo ello es preciso verlo desde nuevas perspectivas críticas.
Predominio de los artesanos en la enseñanza de las primeras letras y su resistencia al proyecto educativo de Simón Rodríguez
Authors: Morán Perugachi José
Published: January 2023

¿Por qué fue rechazado el proyecto educativo de Simón Rodríguez por parte de la Real Audiencia de Caracas? Este artículo plantea como causa la significativa participación de los artesanos como preceptores de la enseñanza de las primeras letras en la escuela informal. Simón Rodríguez y el fiscal Francisco Moreno y Escandón consideraron este accionar como un referente negativo, por ello plantearon una reforma para regular y establecer una educación institucional. Esta práctica de los artesanos cuestionó la idea de educación popular del siglo xix y proyectó un preludio para la educación expandida.
Participación juvenil en procesos de elección popular: un estudio de caso del municipio de Santa Isabel 2020-2023
Authors: Ñáñez Rodríguez José Julián
Published: January 2023

El presente artículo de investigación tiene como objetivo explorar las experiencias de participación de los jóvenes aspirantes al Concejo Municipal de Santa Isabel en las elecciones de 2019. Se determinó un estudio de caso; en primer lugar, se buscaron los antecedentes investigativos en bases de datos institucionales y oficiales, como Scielo, Redalyc y Dialnet. En segundo lugar, se sistematizó la información en una matriz para el análisis. Posteriormente, se diseñaron y aplicaron cinco entrevistas semiestructuradas a tres aspirantes al concejo, al alcalde municipal y a un concejal electo del municipio. El análisis permitió concluir que los argumentos de los entrevistados en torno a la participación política en los concejos municipales carecen de claridad en lo referente a las acciones políticas.