bluuebunny/crossref_metadata_2025 huggingface dataset:
An overview of heat-stress response regulation in Gram-negative bacteria considering Escherichia coli as a model organism
Authors: Paul Deborupa , Ghosh Sanmitra
Published: March 2022

Response to heat stress (HSR) is a key stress response for endurance in Escherichia coli mediated by transcriptional factor σ-32. Even though there has been extensive investigation on the contribution of proteins and chaperones in retaining protein stability in cells under stress conditions, limited information is available regarding the dynamic nature of mechanisms regulating the activity of the highly conserved heat shock proteins (Hsps). Several gene expression-based studies suggest the pivotal role of Hsp70 (DnaK) in the regulation of the expression of heat shock genes (Hsg). Direct interaction of Hsp70 with σ-32 may regulate this function in E. coli.  Recent studies revealed that localization of σ-32 to the membrane interior by SRP-dependent pathway enables them to function appropriately in their role as regulators. The contributions of different cellular components including cell membrane remain unknown. Other cellular components or σ-32 interfere with polypeptides which could play a crucial role in cell survival. Sigma factor monitors and preserves outer membrane integrity of E. coli by stimulating the genes regulating outer membrane proteins (OMPs) and lipopolysaccharide (LPS) assemblage as well as through expression of small RNAs to down-regulate surplus unassembled OMPs. σ-E activity is regulated by the rate at which its membrane-encompassing anti-sigma factor, RseA is degraded. Mutations in rseA are reported to constitutively increase the sigma (E) activity that is validated at both genetic and biochemical levels. In this review, the basic mechanism of heat stress regulation in gram-negative bacteria has been elaborated using E. coli as a model organism.
Leishmaniasis: Plants as a source of antileishmanial agents
Authors: Singh Manoj Kumar , Das Arpita , Saha Rudra P , Paul Joydeep , Nandi Debkumar
Published: March 2022

Leishmania infection causes a group of tropical diseases and has remained neglected for decades. It spreads by sandfly vector and is one of the most fatal protozoan diseases after malaria. Leishmaniases are a group of diseases caused by the infection of different Leishmania species and display clinically different forms like “Visceral leishmaniasis” (VL), “mucocutaneous leishmaniasis” and “cutaneous leishmaniasis” (CL). Approximately one billion people living in an endemic area are at high risk. Three hundred thousand cases of VL are reported annually and around twenty thousand people die every year, proving it as one of the most lethal forms of leishmaniasis. Until now, no effective vaccine could be made. There is an increase in drug resistance in the case of conventional drugs. New synthetic drugs are either too costly or have side effects. Requirements of new drugs are of utmost importance to control this situation. Plants provide a source of unlimited chemical diversity, which can be screened for antileishmanial activities. Moreover, their low cost and less or no side effects make them idle candidates in the search of new antileishmanial drugs.
Amendment of the Corruption Eradication Commission Act and Its Impact on the Constitution
Authors: Monteiro Josef Mario
Published: March 2022

This study analyzed the sub-system factors influencing the amendment of the Corruption Eradication Commission Act (KPK Law) from the Cybernetics theory and the impacts on the Constitution. According to this theory, there are various kinds of sub-systems, where one sub-system is interrelated with other sub-systems. Each of the sub-systems referred to will influence each other based on the primary function of each of these sub-systems, such as the cultural sub-system, which has the primary function of maintaining patterns, the social sub-system as a function of integrity, the political function as a function of achieving goals, and the economic sub-system as an adaptive function. This doctrinal legal research employed statutory approaches and concepts and found that changes in the KPK Law are influenced by the political sub-system factor, particularly the strong political interests of the House of Representatives and the Government. As a result, the amendment to the KPK Law is undemocratic because it does not fulfill the formal and material principles. In addition, it does not philosophically fulfill the function of law, leading to constitutional values violation.
Возможности автопрома Германии в развитии туризма
Authors: Балмусов Ю.С. , Сарайкина С.В.
Published: March 2022

Статья раскрывает особенности использования возможностей автомобильной отрасли Германии для развития туризма. Дается краткая характеристика автопрома страны. Рассматриваются особенности развития таких видов туризма как деловой, промышленный, культурно-познавательный, которые развиваются на основе автомобилестроения.
Перспективы развития Абшерон-Хызынского экономического района на новом этапе районирования
Authors: Иманова С.Г.
Published: March 2022

Экономико-географическое районирование в Азербайджанской Республике проводилось в четыре этапа. По районированию 2021 года образован АбшеронскоХызынский экономический район. В экономический район входят Абшеронский и Хызынский районы, города Сумгаит и Хырдалан. По промышленному развитию отличается город Сумгаит. Здесь функционирует промышленный парк, состоящий из 24 резидента. На территории промышленного парка производятся различные нефтехимические продукты, строительные материалы, оборудования для пищевой промышленности и т.д. Будучи промышленно-аграрным районом, Абшеронский район имеет различные хозяйственные предприятия. Хызынский район расположен вблизи Губа-Хачмазского района и отличается привлекательной природой и историческими памятниками. Абшеронско-Хызынский экономико-географический район с его различными отраслями экономики и возможностями развития туризма играет особую роль в экономическом и социальном развитии республики.
Об одном способе определения дополнительных параметров трещинова-то-пористых сред по результатам гидродинамических исследований скважин
Authors: Овчинников М.Н. , Гаврилов А.Г.
Published: March 2022

Предложен способ расчета постоянных размерности времени и пьезопроводностей блокового и трещинного подпространств трещиновато- пористой среды по результатам проведения комбинации экспериментов методом кривых восстановления давления и фильтрационных волн давления.
Важные аспекты выбора системы управления проектами в строительстве
Authors: Гринько А.Р. , Горбачев А.Ю.
Published: March 2022

Строительство это наиболее развивающаяся область как в России, так и в мире в целом. В составе каждого крупного объекта строительства функционирует большое количество компаний. Так, одни будут отвечать за распределение рабочей силы на площадке, другие – за поставку строительных материалов, третьи – за календарное планирование этапов строительства. Этот список можно продолжать до бесконечности. В каждом проекте взаимодействуют подрядчики, архитекторы, инженеры, клиенты и т.д. Процесс создания продуктивного коллектива не терпит медлительности и халатности, требуется высокий уровень планирования и организации всех отдельно взятых частей проекта. Более прозрачной и отлаженной работу в течении проектирования и строительства могут помочь сделать системы управления проектами в строительстве. В данной статье будут рассмотрены важнейшие аспекты выбора таких систем.
Аэрогель – уникальный материал, используемый в строительстве
Authors: Еременко Р.Б.
Published: March 2022

В статье описана история создания аэрогеля, описаны его составляющие компоненты, учтено и показано использование его в более ранние периоды истории, от момента создания до 2000 года. Плавно совершен переход к важности применения данного материала в строительной сфере, приведены примеры его использования, а также указаны перспективы аэрогеля и его модификаций в строительстве. В результате исследования сделан вывод об уникальности материала, с точки зрения технических характеристик.
Северная Ирландия и брексит
Authors: Руднев В.В.
Published: March 2022

В статье рассматриваются проблемы Северной Ирландии (территории с 17-го века активно колонизировавшейся англичанами), в контексте брексита (выхода Великобритании из Европейского союза). Анализируются исторические события предшествовавшего периода и их влияние на ситуацию в регионе. Особый акцент делается на договоренностях (соглашение Страстной пятницы 1998 г.) обеспечивших мир в регионе после долгого периода конфликтов между католиками и протестантами (1969-1998 гг.) и торговой сделке Великобритании с Европейским союзом (2020 г). Делается вывод о том, что поиск решения проблем региона, в частности границы с Ирландской республикой – актуален для Великобритании. Сегодня «мягкое» решение является желательным для всех сторон, но сложно достижимым.
Привлечение к ответственности за пособничество фашистам на бывших в оккупации территориях СССР: уголовно-процессуальный аспект
Authors: Упоров И.В.
Published: March 2022

В статье раскрываются особенности уголовно-процессуального регулирования вопросов привлечения к юридической ответственности пособников фашистов, участников антисоветских бандформирований на бывших в оккупации советских территориях. Анализируются нормы действовавшего тогда УПК РСФСР, других законов, архивные материалы, научные публикации по заявленной теме. Отмечается, что существенным недостатком советского уголовно-процессуального законодательства был недопуск защитника обвиняемому во время предварительного следствия (официально это не считалось недостатком), однако по другим аспектам советский уголовный процесс соответствовал общепризнанным принципам и позволял по указной категории дел преступлений против государства в целом выносить справедливые приговоры. В работе частично использованы материалы ранних авторских публикаций.
Характер фазообразования в системе NdSb2Se4 –Bi2Se3
Authors: Садыгов Ф.М. , Мамедова С.Г. , Исмаилов З.И.
Published: March 2022

Методами физико-химического анализа изучено диаграмма состояния системы NdSb2Se4 –Bi2Se3, которые являются неквазибинарной сечением тройной системе Nd2Se3- Bi2Se3-Sb2Se3. Обнаружено область твердого раствора вблизи исходных компонентов протяженностью до 2 мол% при комнатной температуре. Установлено, что сплавы системы с содержанием 0-5% и 95 мол% Bi2Se3 однофазны, а остальные сплавы двух и трехфазные. При измерении микротвердости в отшлифованных образцах получили ряд значений, 1570МПа соответствует Nd2Se3 , 930 МПа на Bi2Se3 и 1170МПа соответствует NdSb2Se4, 1250 Мпа, NdBiSe3 3440 МПа Nd2Te3.
Экспресс-контроль моторного масла седельного тягача Volvo FH Truck
Authors: Селиверстов А.А.
Published: March 2022

В статье сообщается о контроле качества моторного масла для седельного тягача Volvo FH Truck в лаборатории «Топливо-смазочных материалов». Экспресс-контроль состояния рабочего и нового моторного масла выполнялся с участием студентов Института лесных, горных и строительных наук.
Моделирование цепей несинусоидального тока
Authors: Анисимова М.С. , Попова И.С.
Published: March 2022

Рассматривается понятие несинусоидальных цепей, причины появления несинусоидальности источника напряжения. Показан инструментарий программы Multisim для анализа цепей, приведены примеры спектрального анализа напряжения источника при наличии в цепи потребителей с нелинейными вольт-амперными характеристиками.
Сердечная созерцательность и чувственность русской культуры
Authors: Васильченко А.В.
Published: March 2022

Рассмотрена чувственно-созерцательная специфика русской литературы и ментальности. Дана характеристика средств русского языка для выражения чувства любви. На основе проведенного анализа автором сделан вывод, что русский язык имеет свои ментальные особенности, которые отражают характер народа и чувство любви является духовно-творческой силой русского человека.
Применение уравнений в частных производных в химии
Authors: Логинова Е.А.
Published: March 2022

Статья посвящена дифференциальным уравнениям в частных производных, описывающим различные процессы и явления в химии. Выписан общий вид уравнения в частных производных, дано определение его решения. Приведен пример начально-краевой задачи: задачи о поглощении газа. Представлены примеры уравнений: уравнение материального баланса для движения несжимаемой жидкости, уравнения фильтрования. Подробно рассмотрен вывод уравнения теплопроводности для движущейся жидкости.
Программное обеспечение для дизайнера интерьера
Authors: Сухопарова Е.В.
Published: March 2022

В статье рассматриваются вопросы применения различных программных комплексов для создания интерьерных композиций.
Performing DoS Attacks on Bluetooth Devices Paired with Google Home Mini
Authors: YÜKSEL Tuğrul , AYDIN Ömer , DALKILIÇ Gökhan
Published: March 2022

In today’s technology world, Virtual personal assistants (VPA) have become very common and most people have started making their homes smart using these VPAs. Although different companies have different assistants, Google Home Mini (GHM) will be our focus in this paper. The first device, Google Home, was released in November 2016 and then GHM was released after a year, in October 2017. GHM has many features such as playing music, setting reminders, setting kitchen timer and controlling smart home devices. Although GHM might be reliable against cyber-attacks, devices, which are paired with GHM, could be attacked and these cyber-attacks can lead to severe problems. Cyber-attack issues become more important to us, specifically if the devices controlled by GHM are vital devices such as oven, fire alarm, security camera. In this article, we will represent Denial of Service (DOS) attacks applied against devices which are paired with GHM. In this study, Bluedoser, L2ping, Bluetooth Dos Script which are software in Kali Linux platform were used in order to perform DoS attack and some devices were used such as Google Home Mini, Headphone, 2 speakers as victim device. Successful results were observed on Bluetooth headphone.
Boron Removal from Colemanite Mine Wastewater by Coagulation using Zinc Hydroxide―A Factorial Optimization Study
Authors: KORKMAZ Mustafa , ÖZMETİN Cengiz , OZMETİN Elif , ÇALGAN Elif , ZİYANAK Öznur
Published: March 2022

In this study, boron removal from synthetic solutions and colemanite mine wastewater by coagulation method using in-situ generated zinc hydroxide from zinc chloride salt was investigated. The parameters for Jar test experiments were solution pH (8-12), concentration (50-750 mg/L), temperature (12-40oC), and zinc chloride dosage (1.0204-10.204 g). The saturation pH of zinc hydroxide is 8.93. The boron adsorption capacity reached to maximum value at pH value of 9 and this pH was selected as optimum value. Boron adsorption capacity increased with increasing concentration due to increasing driving force of concentration. High dosages increased the removal percentage. The adsorption of boron to zinc hydroxide had exothermic nature. The optimum conditions obtained from synthetic solutions were applied to the colemanite mine wastewater by 22 factorial design. The maximum boron adsorption capacity of zinc hydroxide from colemanite mine wastewater was calculated as 43.57 mg/g. The used material and process was promising for boron mine wastewater.
The Quasi Parallel Curve of a Space Curve
Authors: GÜLER Fatma
Published: March 2022

A parallel or offset curve is defined as a curve whose points are a fixed distance from a given curve. These curves are not parallel transport. Often, it has a more complex mathematical structure than the first curve. Offset curves are important in numerically controlled machining, for example, where a biaxial machine defines the shape of the cut made with a round cutting tool. In this study, the quasi parallel curve is defined with the help of the quasi frame of a given curve. According to all selections of the projection vector, the quasi frame equations of this curve are expressed in terms of the quasi elements of the given curve. The curvatures of the quasi parallel curve were obtained depending on the quasi curvatures of the main curve. The study was supported by examples. The examples confirm that the quasi parallel curve is not parallel transport.
Levantine Import in Borysthenes
Authors: BUJSKYKH A.V.
Published: March 2022

Ceramic assemblage from Borysthenes (excavations conducted by V. Lapin, 1960-1980) contains a number of unusual and rare imports – fragments of trading amphoras fabricated at Cyprus and at the numerous cites at Levantine coast. Import from Cyprus is attributed by fragments of two massive and high rounded handles and one rounded base attributed with so called basket-handle amphoras. The parts of some similar amphoras were excavated in Borysthenes in the later times. Import from Levantine coast is represented by four upper parts of jars with small twisted handles and carinated shoulders. This specific type of trading amphoras (Phoenician amphoras) in Borythenes’ ceramic collection is attested for the first time. Their common dating covers the second half of 7th – the very beginning of 6th c. BCE. Studying of these unusual imports for the entire Pontic region provokes a number of questions connected with general problem of Mediterranean sea trade in the archaic period. For Borysthenes it’s an actual question about the presence of direct trading connections with the South-Eastern part of Mediterranean or the use of middle traders and middle ports of trade. The role of Levantine production in the trade via Aegean is not clear yet. Borysthenes emporion opens a new topic for discussion about its role in the Mediterranean and Aegean sea trade, common organisation of this trade and the final customers of wine production, distributed in trading amphoras.
The Sinopian Embassy to Darius III
Authors: SHASHLOVA T.YU.
Published: March 2022

The article deals with the messages of Arrian and Q. Curtius Rufus about the Sinopeʼs embassy sent to Darius III during the Macedonian invasion. After the death of the Persian King, the ambassadors together with the Greek mercenaries, which were at Darius, surrendered to Alexander the Great (Arr. Anab. III.24.4; Curt. VI.5.6–10). The purposes and circumstances of sending embassy in sources don't reveal. However, a number of numismatic data suggest that Sinop had some relation to the Persian counteroffensive that unfolded in Asia Minor after the Battle of Issus (Curt. IV.1.34–35; Diod. XVII.48.5–6). Most likely, sending embassy by this city to Darius III should be connected with these events.
Executive Functions and Reinforcement Sensitivity in Women with Obsessive Compulsive Symptoms
Authors: Amani Malahat , Keyvanlo Safoora
Published: March 2022

Objective: Obsessive-compulsive disorder is associated with cognitive and motivational deficits caused by abnormal activities in certain neural circuits. This study sets out to determine the contribution of each component of executive function and reinforcement sensitivity in prediction of obsessive-compulsive symptoms.
Method: In this cross-sectional study, the study population consisted of all adult women living in Sabzevar city (Iran). Using cluster sampling, 365 women were selected as the study sample. Participants completed the Obsessive-Compulsive Inventory, Sensitivity to Punishment and Sensitivity to Reward Questionnaire - Revised and Clarified (SPSRQ-RC) as well as Behavior Rating Inventory of Executive Function (BRIEF). Data analysis was conducted using correlation and regression tests.
Results: The results of stepwise regression analysis showed that inhibition, shift and initiation variables as well as sensitivity to punishment and reward were best predictors of obsessive-compulsive symptoms (adjusted R square = 0.34, F = 38.93, P < 0.0001).
Conclusion: It seems that impaired executive functions in cognition and sensitivity to reinforcement in motivation contribute to the emergence or sustainability of obsessive-compulsive symptoms.
Quantitative and Qualitative Measurement of Vaginal Fluid β-HCG for the Diagnosis of Premature Rupture of Membranes
Authors: Marfoo Javad , Masihi Sara , Motamedinasab Maryam
Published: March 2022

Background: Premature rupture of membranes (PROM) is known as one of the leading causes of morbidity and mortality among pregnant women. So, the aim of this study was to evaluate the diagnostic value of quantitative and qualitative vaginal fluid β-HCG for the detection of premature rupture of membranes.
Methods: One hundred pregnant women with gestation age between 28 and 37 weeks were divided into three groups: confirmed PROM group (34 cases), suspected of PROM (36 cases), and intact membranes (30 cases). Those pregnant women with positive pooling tests were considered as confirmed PROM, while those with the decreased amniotic fluid index, positive nitrazine, or ferning were included in suspected PROM group. Notably, pregnant women with no complaints or complications were enrolled as the control group. Five ml sterile normal saline was injected into the posterior fornix of vagina, vaginal fluid was aspirated, and β-HCG measurement was then performed both quantitatively and qualitatively using ELISA and baby check kits, respectively.
Results: The cut-off value for quantitative β-HCG was determined as 66 mIU/m. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of quantitative β-HCG were calculated as 97.05%, 100%, 100%, 96.77%, and 98.43%, respectively. Besides, the qualitative vaginal washing fluid β-HCG using Baby check with the threshold value of 25 mIU/ml had 94.11% sensitivity, 93.33% specificity, 94.11% PPV, 93.33% NPV, and 93.75% accuracy.
Conclusion: Quantitative and qualitative vaginal washing fluid β-HCG measurements are accurate, reliable, and useful tests for the diagnosis of PROM.
Inborn Errors of Metabolism Referrals- Shahid Sadoughi Hospital: A Cross- Sectional Study
Authors: Mirhosseini Naser Ali , Nadjarzadeh Azadeh , Golzar Azam , Fallah Tahereh , Sadri Zahra
Published: March 2022

Background: Inborn Errors of Metabolism (IEMs) are a group of heterogeneous disorders resulting from absent or decreased metabolic pathway activity. They are typically rare, but are more common in consanguineous population.
Methods: In this cross sectional study, all children with symptoms suspicious for IEMs who referred to Shahid Sadoughi Hospital in Yazd during a 5-year period (2013-2018) were investigated for metabolic diseases. The diagnoses were further confirmed by clinical symptoms and biochemical analysis. IEMs type, age of diagnosis, family history and disease outcome were recorded.
Results: In this study, 39 symptomatic children with a median age of 48 months were diagnosed with different types of metabolic diseases. About 64.1% of the patients were born from consanguineous marriage. The patients’ mean age at the time of diagnosis was 25.3 ± 5.1 months. The most frequent disorders were organic acidemias which were found in 12 patients (30.8%), lysosomal storage disorders which were found in 8 patients (20.5%), and amino acid disorders excluding phenylketonuria which was found in 8 patients (20.5%). Most of the patients (60%) were diagnosed before the age of 6 months. Mortality from metabolic disorders was 5 (12.8%). The rest of the patients (22 cases, 56.4 %) had developmental delay.
Conclusion: It was found that the prevalence of inherited metabolic disorders was higher in countries with a high prevalence of consanguineous marriage, such as Iran. More extensive newborn screening is needed for ensuring early diagnosis of these patients given that delay in diagnosis of this disorder may be associated with high morbidity and mortality.
Prevalence of Sepsis among Iranian Newborns with Jaundice: A Meta-Analysis Based on Cross-Sectional Studies
Authors: Ekraminasab Sedigheh , Manzourolhojeh Mohammad
Published: March 2022

Background: Jaundice is a common life-threatening disease in the neonates. Several factors play a role in the etiology of jaundice. Sepsis is a possible cause of jaundice after blood group incompatibility. Bacterial infection and jaundice may be associated with higher morbidity. To date there exists no systematic review and meta-analysis that evaluated the Prevalence of sepsis in Iranian newborns with jaundice. Thus, in this study we evaluated the prevalence of sepsis among Iranian newborns with jaundice.
Methods: A comprehensive literature search in Persian and English was performed on PubMed, Web of Sciences, Scopus, Google Scholar, Magiran and Scientific Information Database (SID) till July 2021. Data analysis was done by CMA version 2.0 software.
Results: A total of eight publications with 4434 newborns with jaundice out of approximately 105 retrieved articles were selected. 211 neonates had sepsis. Pooled data revealed that the overall prevalence of sepsis among Iranian newborns with jaundice was 4.7% (95% CI 0.041-0.202, P ≤ 0.001) and there was no publication bias.
Conclusion: This study showed that the prevalence of sepsis among Iranian newborns with jaundice was 4.7% and sepsis was a plausible reason of unexplained Hyperbilirubinemia among newborns with jaundice. To better understand the relationship between jaundice and sepsis, more studies with large sample sizes are needed.
The distribution and the related factors of forward head posture among medical students
Authors: KÖSE Elif , BAYLAN Hüseyin , KARAHAN Hilal , EKERBİÇER Hasan
Published: March 2022

Objective: Forward head posture (FHP) is becoming common in medical students who study for long durations with wrong postures due to intensive curriculum. This study was conducted to determine the frequency of FHP and related factors in medical students.

Method: The first and second-year medical students filled out the questionnaire including sociodemographic characteristics, activity status, Smartphone Addiction Questionnaire, Beck Depression, Body Awareness, and Perceived Stress Scales after their verbal consent was obtained. FHP and craniovertebral angle values were measured.

Results: 47% of the students had highly severe (≥5 cm), 46.2% had severe FHP (2.5-5 cm), and 6.8% had mild FHP. The mean CVA (Costovertebral Angle) values were determined as 44.31 ± 4.31. The frequency of students whose CVA values are below 45° is 59.3% (140 people). The frequency of highly severe FHP was also found as high in the taller, in males, and in the students with high BMI. In the regression model examining the situations that increase the risk of severe FHP, it was found that depression increased the risk of FHP 2.5 times.

Conclusion: FHP was found to be very common (90%) in medical students. FHP was found to be more severe in students with high depression scores.
Elementos sociopolíticos e econômicos refletidos no encarceramento de menores em conflito com a lei em moçambique (2016-2018)
Authors: Cruzio Beatriz
Published: March 2022

A constatação do crescente número de menores encarcerados torna-se mais evidente quando se verifica a fraca discussão do tema como um elemento de politização e sociabilização. Por isso, a pesquisa foi realizada com vista a verificar como ocorre o processo de ressocialização dos menores encarcerados, bem como fazer uma avaliação do sistema penitenciário moçambicano. Os resultados demonstram que a realidade vivenciada pelos menores encarcerados nos estabelecimentos prisionais em Moçambique é construída ao longo de uma mesma moldura política e de um mesmo sistema de governação, de contextos históricos e de conceitos da sociedade em geral. A pesquisa decorreu dentro dos recintos dos Estabelecimentos Penitenciários das Províncias de Maputo, Manica e Nampula, nos meses de outubro e novembro de 2017, agosto, setembro e outubro de 2018, agosto e setembro de 2019. Relativamente à população-alvo, nas três províncias, o universo foi constituído por um total de 191 menores do sexo masculino, cujas idades variam de 16 aos 18 anos, independentemente do nível económico, escolaridade e do ato infracional que tenham cometido.
The Concept of an Individual Style in Postmodern Architectural Graphics
Authors: Perepelytsia Oksana , Hryhorieva Valentyna , Konshyna Olena , Kucherenko Kateryna , Melnyk Nataliia , Kubrysh Nataliia , Karpova Svitlana
Published: March 2022

The article deals with the essence and genesis of an individual style in postmodern architectural graphics as a special signature of creativity. It considers conceptual and terminological issues regarding the concept of “architecture”, “architectural graphics”, and “an individual style”. Besides, the article shows that the knowledge of architectural graphics makes it a powerful visual tool in any kind of design activity. In the current post-industrial period, manual graphics acts as an individual unit. An individual style is always formed based on a specific personal programme, whose postulates influence the architect’s work. The international relevance of the article lies in a new approach to the concept of “style” in postmodern architectural graphics. In turn, it allows one to discover new methodological guidelines for its formation.
E-Learning in a Postmodern Society
Authors: Yuskovych-Zhukovska Valentyna , Bogut Oleg , Lotyuk Yuriy , Kravchuck Olga , Rudenko Olga , Vasylenko Halyna
Published: March 2022

The relevance of the chosen direction of research is that e-learning at the present stage of development of society is one of the most popular forms of organization of the educational process. This primarily applies to vocational and postgraduate education. Its main advantage is that it focuses on creating a barrier-free learning environment, ensuring the availability of quality education without separation from work and family and regardless of the place of residence.
The article analyzes the features of updating the education system in the postmodern era and the urgent problems of the education system that need to be addressed (improvement of national educational legislation; changing the image of research and teaching staff; preservation of classical universities; change of system and support for business, which is used to develop science and education; securing the technical and technological needs of the education system). Features of e-learning as a means of meeting the demand for educational services, its advantages and disadvantages are characterized. The peculiarities of functioning of open educational resources as prospects of e-learning development are analyzed.
Continuation of the initiated research is to study the specific characteristics of mobile learning as one of the possible options for e-learning.
Post-pandemic Trends in the Development of Social State Institutions
Authors: Vasiliev Vladimir Petrovitch
Published: March 2022

The article analyzes the new conditions and institutions of socio-economic dynamics developing under the influence of COVID-19 and overcoming its consequences. New directions of the macro-management system are actualized by the economic recession that arose under the influence of COVID-19 and the previous depressive rates of economic growth. Social conditions and tensions have predetermined the growth of the state's participation in socio-economic development, the formation of new institutional trends.
Transformation of public administration institutions is due to the long-term influence of the characteristics of the information society and the conceptualization of modern sustainable growth in the areas of welfare, poverty reduction, and ecology. In the Russian Federation, a transition is underway to a new form of institutional regulation of socio-economic dynamics based on a system of medium-term strategic planning in the range from the development of key long-term development strategies to the operational management of specific projects. The modern national development goals and their indicators are presented, the existing risks of strategic planning are structured, which require consideration when developing subsequent system solutions. The current principles of the welfare state have been clarified, institutional innovations in the organization of social protection of the population are shown in the context of strategic planning, the interaction of federal and regional authorities in the problem field of social assistance and social insurance of the population.
Why Don't We Get Vaccinated? Some Explanatory Hypotheses of Vaccine Hesitation
Authors: Rotila Viorel
Published: March 2022

Because inappropriate built-in or managed vaccination campaigns, regardless of the causes of vaccine hesitation, can have side effects, the most important being the opposition to vaccination, the understanding of vaccination hesitation can have an influence on specific public policies. In this article we identify a set of possible explanations for vaccine hesitation, which can be used to assess situations, identify problems and adopt appropriate solutions. We highlight the fact that the vaccination hesitation is not just about vaccination, the approach of identifying explanatory hypotheses involves identifying all relevant frames of reference, all social areas that participate in establishing the appropriate interpretation context. The level of compliance with the rules could be an important explanatory hypothesis for the differences between different states in the share of vaccinated citizens. Other explanatory hypotheses: the structure of epistemic communities, community and individual cognitive resources on strategies facing the uncertainty and risk, distrust. We also assess the limits of using the deficit model. We keep in mind two cognitive asymmetries: inaction is perceived as less risky or responsible than action; the indecision is in a similar situation to the decision. Because the values that people adhere reflect their personal beliefs and convictions, and they guide the way they seek, receive, and interpret information, strategies to reduce vaccine hesitation should be based on verifying the compatibility of the intended outcome with individual values and to continue testing the various solutions to change the beliefs that contribute to the determination of vaccine hesitation or refusal.
Wykorzystanie autobiograficznego wywiadu narracyjnego w badaniach nad konstruowaniem obrazu przeszłości w biografii. Na przykładzie socjologicznego porównania narracji na temat życia w PRL-u i NRD
Authors: Kaźmierska Kaja , Schütze Fritz
Published: March 2022

Przedmiotem artykułu jest pokazanie możliwości zastosowania badań biograficznych, a ściślej wywiadu autobiograficzno-narracyjnego, w badaniach nad biograficznym i społecznym obrazem przeszłości. Zostanie to ukazane na konkretnym przykładzie projektu badawczego. Przy czym nie są tu prezentowane ani przebieg, ani wyniki badań, ale założenia teoretyczne i metodologiczne, które umożliwiły konceptualizację problematyki i zarysowanie wstępnych ram interpretacyjnych związanych z projektem badania konkretnych zjawisk i procesów społecznych. Autorzy chcą w ten sposób pokazać możliwość wykorzystania badań biograficznych, które w tej perspektywie nie są jedynie metodą gromadzenia i analizy materiałów empirycznych, ale wyznaczają określony sposób myślenia o interesującej autorów problematyce. Celem projektu jest zbadanie polskiego i niemieckiego doświadczenia socjalizmu obejmującego lata 1945–1989.
Badacz z Polski na Ukrainie: problemy metodologiczne
Authors: Wylegała Anna
Published: March 2022

Celem artykułu jest analiza metodologicznych aspektów prowadzenia badań w obcym kulturowo środowisku, w sytuacji różnic językowych i różnych identyfikacji narodowych badacza i rozmówcy. Analiza problemu podjęta została na przykładzie badań terenowych zrealizowanych przez polską badaczkę na Ukrainie. Staram się odpowiedzieć na pytanie, czy odmienna narodowość ma w takiej sytuacji wpływ na interakcję z rozmówcami oraz otrzymywany materiał, czy jest ona obciążeniem czy zaletą, a także w jaki sposób można ten wpływ kontrolować. Interesuje mnie kwestia kontaktu z rozmówcami i interakcji podczas samego wywiadu oraz różnego rodzaju przypadki modyfikowania narracji przez rozmówcę ze względu na odmienną identyfikację narodową badacza. Prezentację poszczególnych problemów pojawiających się w toku realizacji badań i analizy materiału ilustruję fragmentami nagranych w ramach badań wywiadów.
Remote Teaching Strategies in Writing Skill Development Due to Covid-19 Pandemic
Authors: Lestari Hernina Dewi , Hartatik Sri Fatmaning
Published: March 2022

Covid-19 pandemic inevitably affects educational practices including in teaching writing. It leads to the unfamiliar challenges for those who are in charge, in this case English instructors. Conducted using descriptive qualitative design, this study aims at describing teaching writing strategies to make high-impact improvement for students' writing performance despite their teaching and learning process has to deal with technological and technical challenges. Thus, the researchers suggested several points to focus on; they were punchy topic selection, meaningful purpose, detailed instruction, excellent feedback, peer review to improve metacognition, and reasonable-targetted grading. The researchers found that teaching strategies that were reasonably effective in virtual classroom were choosing punchy topic to gather the students' interest in developing their writing, delivering meaningful purpose of writing to set the boundaries to make a high quality writing, preparing detailed instruction to minimize any misinterpretation from the students, giving excellent feedback so that the students' writing were thoroughly appreciated and corrected, including peer review section to gain metacognition practice, and setting reasonable-targetted grading to motivate the students without giving burden. Even though the strategies may be particular to remote context, additional research result in face-to-face setting is welcomed to enrich the knowledge development especially in teaching writing.
The English Language Needs for Information Technology: A Comparison Case of Professionals and Students
Authors: Prasetya Rizky Eka
Published: March 2022

English has established itself as a global lingua franca. The global growth in the usage of English has resulted in many reforms within educational institutions. The study aims to ascertain and examine English needs for information technology purposes among professionals and learners on a wide scale. A quantitative descriptive approach with a survey research design was employed in the study, and it applied to the Cross-Sectional survey design. Mailed questionnaires were collected from 243 students’ and 23 professionals. According to the questionnaires, the result found that professional purposes for learning English are to complete written-project reports or papers, while students must communicate with the global community. The English learning outcome implied different aims. The professionals want to complete language instructions for information technology processing, but students expect information access to the products. Professional speaking abilities are concerned with asking clarifications in the group or personal meetings, yet students concern more in taking and receiving the phone calls. In the same manner as writing, professionals and students have the same expectation that is to produce formal reports in academic or professional situations. Both participants perceive the responses by reading ability concerned to the summarizing detail information. This study affirmed an interrelation between the English standing in professional IT and students’ IT positions in communication experiences in their present circumstances.
RENATURALIZAÇÃO DE RIOS: UM CAMINHO RUMO À SUSTENTABILIDADE URBANA
Authors: Azevedo Motta Sucupira Alana , Lopes de Andrea Theresa Raquel , Michiko Passos Okawa Cristhiane
Published: March 2022

Os rios são fontes de água fundamentais para o homem desde o princípio das primeiras cidades. A urbanização sempre esteve ao leito dos rios e, consequentemente, eles começam a ser degradados e esquecidos pela sociedade. Considerado um obstáculo para o desenvolvimento urbano, era frequentemente canalizado e escondido da população. A urbanização provoca um aumento considerável na impermeabilização do solo e, sem áreas para infiltração da água da chuva, as cidades começaram a sofrer com enchentes e inundações. A renaturalização é uma das técnicas para recuperar rios degradados e modificados pelo homem, devolvendo a eles as condições próximas as naturais. Grandes desafios são encontrados para executar tais medidas, como a disponibilidade de recursos financeiros, incentivos públicos, questões sociais políticas. Por outro lado, a busca pela sustentabilidade e pelos Objetivos do Desenvolvimento Sustentável definidos pela ONU mostram que é possível conciliar os interesses ambientais, sociais e econômicos e promover qualidade de vida.
Post-traumatic lymphedema: review of the literature and surgical treatment options
Authors: Minasian Raquel A. , Samaha Yasmina , Brazio Philip S.
Published: March 2022

Post-traumatic lymphedema (PTL) is a complex, debilitating, and potentially common disease which has received limited attention to date. The available literature is reviewed to identify injury patterns and critical lymphatic areas associated with the disease. A deeper understanding of these critical anatomic regions allows the reconstructive surgeon to potentially identify PTL patients earlier in order to apply surgical and nonsurgical interventions in the acute phase, improving lymphatic physiology and, ultimately, patient outcomes. Current diagnostic and treatment approaches are discussed in detail, with a focus on lymphatic microsurgical techniques developed and applied to PTL within the last decade.
Eyelid defect reconstruction
Authors: Somenek Michael
Published: March 2022

Eyelid reconstruction remains one of the more challenging areas of the face to reconstruct due to its dynamic complexity. They play an essential role in protecting the globe, forming a barrier against trauma, excessive light, and pumping tears towards the nasolacrimal duct system. A critical understanding of the anatomy and soft tissue reconstructive options is essential to properly reconstruct the eyelid and maintain the functional and cosmetic components.
Protective benefit of minimally invasive liver surgery for hepatocellular carcinoma prior to transplant
Authors: Khouzam Simone , Pagano Duilio , Barbara Marco , Di Marco Vito , Pietrosi Giada , Maringhini Marco , Canzonieri Marco , Calamia Sergio , Gruttadauria Salvatore
Published: March 2022

Aim: The purpose of this study is to assess the benefit of laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) given recurrence and future need for liver transplantation (LT). Methods: Data on liver resections were gathered from the Istituto di Ricovero e Cura a Carattere Scientifico-Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (IRCCS-ISMETT) from 2003-2021. A retrospective analysis of 1408 consecutive adult patients who had a liver resection was performed with categorization based on the underlying disease process. A sub-analysis studied the 291 patients who had an LLR with an intention to transplant approach after LLR. Results: From 2012 to 2020, ISMETT’s mean annual LLR rate was 45%. Data suggests that a laparoscopic approach to iterative surgical treatment for HCC has demonstrated protective benefits. Compared to open surgery or LT, LLR is protective against the risk of de-listing, post-transplant patient death, tumor recurrence, adhesions, and bleeding in a cirrhotic patient. Kaplan Meier’s analysis showed no difference between post-LT survival curves for those with prior open abdominal surgery or LLR (P = 0.658). Conclusion: Laparoscopic surgery has important protective advantages over laparotomy surgery for the surgical treatment of HCC, particularly since treatment is not always curative. LLR can be considered a bridge therapy for transplantation, ensuring less crowding of waiting lists, a desirable condition in areas of donor storage.
Clinical application of cardiac scintigraphy with bone tracers: controversies and pitfalls in cardiac amyloidosis
Authors: Mattana Francesco , Muraglia Lorenzo , Girardi Francesca , Cerio Ivan , Porcari Aldostefano , Dore Franca , Bonfiglioli Rachele , Fanti Stefano
Published: March 2022

Cardiac amyloidosis (CA) is a life-threatening disease caused by extracellular deposition of amyloidogenic proteins in the heart tissue; it could be associated with a poor prognosis and remains underdiagnosed and underestimated. During the last years, bone scintigraphy has been widely used to facilitate the diagnosis of CA, avoid endomyocardial biopsy, and differentiate amyloid light-chain amyloidosis from transthyretin amyloidosis. Technetium-99m pyrophosphate (99mTc-PYP) is the most used tracer in the United States, but a standardized and shared acquisition protocol is still lacking; technetium-99m 3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) is widely used in Europe and can count on a more grounded data than 99mTc-PYP. Both tracers suffer from some diagnostic limitations (due to their biochemical characteristics) and pitfalls that can lead to a misdiagnosis of CA. We aim to briefly describe the main differences between 99mTc-PYP and 99mTc-DPD, analyzing the data available in the literature and highlighting the most frequent causes of misdiagnosis and pitfalls. Both 99mTc-DPD and 99mTc-PYP show good accuracy for the diagnosis of CA with high specificity and sensibility. Nevertheless, to achieve this accuracy, the correct acquisition protocols must be followed for each tracer, as suggested in the latest recommendation. Proper diagnosis of CA has a crucial role in patient management; therefore, it is important for nuclear physicians to have the most specific approaches in acquiring and interpreting bone scintigraphy for transthyretin cardiac amyloidosis.
Cardiovascular involvement in multisystem inflammatory syndrome in children with COVID-19
Authors: Misra Amrit , Safa Raya , Sanil Yamuna , Blake Jennifer M. , Eddine Ahmad Charaf , Balakrishnan Preetha , Garcia Richard U. , Aggarwal Sanjeev , Singh Gautam
Published: March 2022

In children, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections typically result in a less severe coronavirus 19 (COVID-19) presentation than in adults. However, a subset of children presents with severe multisystem inflammation associated with recent SARS-CoV-2 infection or COVID-19 exposure in the previous weeks. The Center for Disease Control (CDC) has termed this condition a multisystem inflammatory syndrome in children (MIS-C). MIS-C causes significant cardiovascular involvement, which can be a determinant of clinical course and outcomes. A subset of MIS-C patients presents with hypotension and shock either from acute myocardial dysfunction or systemic vasodilation, with at least of third of patients developing cardiac manifestations from the illness. In addition, myocarditis, pericarditis, valvular regurgitation, coronary artery involvement, and arrhythmias have been reported, with a smaller subset of patients requiring extracorporeal membrane oxygenation. Here, we report our institutional experience of MIS-C over the last year and present a narrative review of cases reported in the literature. In addition, we discuss the clinical protocol of diagnosis and acute and follow-up management of these patients with MIS-C.