bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrowinning of Neodymium Metal Using FLiNdBa Molten Salt
Authors: Cho Sung-Wook , Yu Jeong-Hyun
Published: January 2022

Neodymium is the most used of rare earth elements. Its demand is rapidly increasing as the raw material for Nd-Fe-B permanent magnets. In the present study, the preparation of neodymium metal by molten salt electrowinning was investigated, using the support salt of LiF:NdF3:BaF2 = 7.5:67.4:25.1 (in wt%, FLiNdBa). It focused particularly on the effects of the electrowinning temperature, the cathodic current density, and the feeding rate of the raw material (Nd2O3) on the current efficiency. The current efficiency decreased almost linearly with the electrowinning temperature regardless of the cathodic current density in the temperature range (1030~1130 oC). Considering current efficiency and workability, the most suitable electrowinning temperature was 1040~1050 oC. The current efficiency increased linearly with the cathodic current density in the range of 1~4 A/cm2 irrespective of the electrowinning temperature. The effect of the feeding rate of the raw material (Nd2O3) on the current efficiency showed the same tendency as that of the cathodic current density on the current efficiency. The current efficiency of 73.6% and the metal purity of 99.8% were achieved in this study when the cathodic current density was 3.6 A/cm2 and the electrowinning temperature was 1045 oC.
FORMATION OF THE COMMUNICATIVE COMPETENCE OF THE PERSONALITY BY MEANS OF LANGUAGE
Authors: Khamska Nelina , Polyanska Catherine , Umanska Juliia
Published: January 2022

The purpose of the article is to clarify the features of the formation of a person’s communicative competence by means of language and to define the concept
of “communicative competence”.
The research methodology assumed the use of general scientific methods (analysis,
synthesis, specification, classification). Various methods of pedagogical research were
used: a meaningful analysis of scientific and theoretical concepts; study of works on topical problems of communicative competence; synthesis and generalization of psychological, pedagogical, linguistic and methodological literature; observation, generalization of advanced pedagogical experience to study the state of elaboration of the problem of the formation of a person’s communicative competence.
The scientific novelty of the results obtained lies in the concretization of the
concept of «communicative competence», considered as a result of the formation of professional competence and personal qualities of an individual. Which allow you to establish psychological contact with other people, logically, scientifically and concisely convey information, manage the communication process and organize
communication with others.
Conclusions. The analysis and generalization of theoretical and practical research
on the problem of the formation of a person’s communicative competence is carried
out. The concepts of «communicative competence», the essence and features of the
communicative competence of its components are considered. The levels of linguistic
culture have been determined and it has been established that any professional activity requires certain linguistic and cultural skills in oral and written forms. It has been established that the formation of communicative competence is aimed at developing a culture of verbal communication, the basis of which is communicative skills.
Key words: competence, communicative competence, language, language culture,
language and communication skills.
Deformation Differences in Complex Structural Areas in the Southern Sichuan Basin and Its Influence on Shale Gas Preservation: A Case Study of Changning and Luzhou Areas
Authors: He Shun , Qin Qirong , Li Hu , Wang Shilin
Published: January 2022

Preservation conditions are the key factors that determine the effective accumulation of shale gas. The damage of faults formed by differential structures to the roof and floor and the shielding of lateral edges are the direct reasons for the difference in preservation conditions. Taking the organic-rich shale of the Wufeng–Longmaxi Formation in the south of the Sichuan Basin as an example, this paper reveals different types of shale gas-rich structures by using typical seismic profiles and puts forward the main controlling factors of different gas-rich structures and their influence on preservation. The results show that three kinds of gas-rich structures are developed in the Wufeng–Longmaxi Formation in southern Sichuan: positive type, negative type, and fault transformed slope type. The basin is dominated by a wide and gentle syncline, fault spreading fold, and low scope concealed anticlines. Wide and gentle anticline, arc anticline, and fault transformation slope are developed at the basin edge. Fault sealing is the main controlling factor for the preservation of shale gas in wide and gentle anticlines. The main controlling factors for the preservation of circular arc anticlines and hidden anticlines are anticline curvature and the distance between faults. The preservation of shale gas in a syncline is mainly controlled because it includes formation buried depth, foliation development degree, and formation dip angle. The preservation of fault transformed syncline is mainly affected by formation buried depth, dip angle, and fault sealing. Foliation and faults form a three-dimensional migration system, which jointly controls the intensity of gas escape. Positive structures such as wide and gentle anticline and circular arc anticline at the basin edge, and deep buried gentle syncline and low scope concealed anticline in the basin are favorable shale gas-rich structures.
A Five-Gene Signature Associated With DNA Damage Repair Molecular Subtype Predict Overall Survival for Hepatocellular Carcinoma
Authors: Huo Junyu , Fan Xinyi , Qi Bingxin , Sun Peng
Published: January 2022

Background: DNA damage repair (DDR) is an important mechanism for the occurrence and development of hepatocellular carcinoma (HCC), but its impact on prognosis has not been fully understood.

Materials and methods: A total of 904 HCC patients were included in our study, TCGA (n = 370) and GSE14520 (n = 239) were merged into a large-sample training cohort (n = 609). The training cohort was clustered into C1 and C2 based on prognostic DDR-related genes, the differentially expressed genes (DEGs) between C1 and C2 were identified by the Wilcoxon signed-rank test referred to criteria (|log2FC|≥1 and FDR< 0.05). The univariate Cox analysis was used to screen the prognostic-related DEGs, and Lasso penalized Cox regression analysis was used to construct the risk score. The patients were clarified into high- and low-risk groups based on the median risk score. ICGC (n = 231) and GSE116174 (n = 64) cohorts were used for external validation of the risk score’s prognostic value.

Results: The Kaplan–Meier survival analysis showed that the high-risk group had a significantly reduced overall survival (OS) compared to the low-risk group in the three independent cohorts, and the time-dependent ROC curve showed that the five-gene (STMN1, PON1, PLOD2, MARCKSL1, and SPP1) risk score with a high accuracy in predicting OS. The patients with AFP >300 ng/ml, tumor poor differentiation (grade 3–4), micro and macro vascular tumor invasion, advanced stage (AJCC III-IV, BCLC stage B-C, and CLIP score >2) exhibited a higher risk score. Subgroup survival analysis found that the risk score was applicable to patients with different clinical characteristics. GO and KEGG functional enrichment analysis revealed that cell cycle, p53 signaling, TNF signaling-related pathways were upregulated in the high-risk group. The higher infiltration level of activated CD4 T cell, CD56 bright natural killer cell, plasmacytoid dendritic cell, and type 2 T helper cells were found to lead an unfavorable impact on the OS of HCC patients, and these four kinds of immune cells exhibited a higher infiltration level in the high-risk group.

Conclusion: The five-gene risk score proposed in the research may provide new insights into the individualized evaluation of HCC prognosis.
Women in Neuromodulation: Innovative Contributions to Stereotactic and Functional Neurosurgery
Authors: Heiden Petra , Pieczewski Julia , Andrade Pablo
Published: January 2022

Stereotactic neurosurgery emerged in the mid-20th century following the development of a stereotactic frame by Spiegel and Wycis. Historically women were underrepresented in clinical and academic neurosurgery. There is still a significant deficit of female scientists in this field. This article aims to demonstrate the career and scientific work of some of the most important women who contributed to the development of stereotactic and functional neurosurgery. Exceptional women from all over the world, represented in this review, assisted the evolution of modern stereotactic and functional neurosurgery as neurosurgeons, neuropathologists, neurologists, neurophysiologists and occupational therapists. Fortunately, we could conclude that in the last two decades the number of female researchers has increased significantly.
Research Progress of Bile Acids in Cancer
Authors: Fu Junhao , Yu Min , Xu Wenxia , Yu Shian
Published: January 2022

Bile acids (BAs) were originally known as detergents to facilitate the digestion and absorption of lipids. And our current knowledge of BAs has been extended to potential carcinogenic or cancer suppressor factors due to constant research. In fact, BAs were regarded as a tumor promoters as early as the 1940s. Differential bile acid signals emitted by various bile acid profiles can produce distinct pathophysiological traits, thereby participating in the occurrence and development of tumors. Nevertheless, in recent years, more and more studies have noticed the value of BAs as therapeutic targets. And several studies have applied BAs as a therapeutic agent for various diseases including cancer. Based on the above evidence, we acknowledge that the role of BAs in cancer has yet to be exploited, although considerable efforts have been made to probe the functions of BAs. In this review, we describe the characteristics of BAs as a double-edged sword in cancer, hoping to provide references for future cancer treatments.
Outcomes of Liver Resection for Metabolic Dysfunction-Associated Fatty Liver Disease or Chronic Hepatitis B-Related HCC
Authors: Liu Lei , Xie Si , Teng Yu-Xian , Deng Zhu-Jian , Chen Kang , Liu Hao-Tian , Huo Rong-Rui , Liang Xiu-Mei , Guo Ping-Ping , Yang Da-Long , Ma Liang , Xiang Bang-De , Li Le-Qun , Zhong Jian-Hong
Published: January 2022

Aims

This study aims to determine differences in severity of background liver disease at hepatocellular carcinoma (HCC) diagnosis and long-term survival outcomes among patients undergoing liver resection for HCC in the background of metabolic dysfunction-associated fatty liver disease (MAFLD) compared to chronic hepatitis B (CHB) alone or concurrent CHB (CHB/MAFLD).

Methods

Patient demographics and comorbidities, clinicopathologic data, perioperative and long-term outcomes among patients who underwent liver resection for HCC were reviewed. Overall and recurrence-free survival were calculated with the Kaplan-Meier method, with the values compared using the log-rank test.

Results

From January 2014 to December 2018, 1325 patients underwent potential curative liver resection of HCC; 67 (5.0%), 176 (13.3%), and 1082 (81.7%) patients had MAFLD alone, CHB concurrent with MAFLD, and CHB alone, respectively. At HCC diagnosis, fewer MAFLD patients had cirrhosis, alpha fetoprotein concentration ≥ 400 ng/mL, tumor size ≥ 5 cm, mulinodular, microvascular invasion, receiving major hepatectomy, and receiving adjuvant transarterial chemoembolization. After a median follow-up of 47 months after liver resection, MAFLD (or MAFLD plus CHB/MAFLD) patients had significantly higher overall and recurrence-free survival than CHB patients before or after propensity score analysis (all P<0.05).

Conclusion

Patients with HCC in the setting of MAFLD have less-severe background liver disease at HCC diagnosis and better long-term survival after curative liver resection compared to counterparts with CHB/MAFLD or CHB.
Effects of Propofol Versus Sevoflurane on Postoperative Breast Cancer Prognosis: A Narrative Review
Authors: Fang Panpan , Zhou Jiaqi , Xia Zhengyuan , Lu Yao , Liu Xuesheng
Published: January 2022

Perioperative interventions produce substantial biologic perturbations which are associated with the risk of recurrence after cancer surgery. The changes of tumor microenvironment caused by anesthetic drugs received increasing attention. Till now, it’s still unclear whether or not anesthetic drugs may exert positive or negative impact on cancer outcomes after surgery. Breast cancer is the most common tumor and the leading cause of cancer deaths in women. Propofol and sevoflurane are respectively the most commonly used intravenous and inhaled anesthetics. Debates regarding which of the two most commonly used anesthetics may relatively contribute to the recurrence and metastasis vulnerability of breast cancer postoperatively remain. This review aimed to provide a comprehensive view about the effect of propofol versus sevoflurane on the prognosis of breast cancer obtained from pre-clinical studies and clinical studies. Laboratory and animal studies have demonstrated that sevoflurane may enhance the recurrence and metastasis of breast cancer, while propofol is more likely to reduce the activity of breast cancer cells by attenuating the suppression of the immune system, promoting tumor cells apoptosis, and through other direct anti-tumor effects. However, retrospective clinical studies have shown contradictory results about the effects of propofol and sevoflurane on long-term survival in breast cancer patients. Furthermore, recent prospective studies did not identify significant differences between propofol and sevoflurane in breast cancer metastasis and recurrence. Therefore, more preclinical studies and randomized controlled studies are needed to guide the choice of anesthetics for breast cancer patients.
Cycloastragenol Attenuates Osteoclastogenesis and Bone Loss by Targeting RANKL-Induced Nrf2/Keap1/ARE, NF-κB, Calcium, and NFATc1 Pathways
Authors: Wang Gang , Ma Chao , Chen Kai , Wang Ziyi , Qiu Heng , Chen Delong , He Jianbo , Zhang Cheng , Guo Ding , Lai Boyong , Zhang Shuangxiao , Huang Linfeng , Yang Fan , Yuan Jinbo , Chen Leilei , He Wei , Xu Jiake
Published: January 2022

Osteoporosis, which typically affects postmenopausal women, is an osteolytic disease due to over-activation of osteoclasts. However, current drugs targeting osteoclast inhibition face various side effects, making natural compounds with great interest as alternative treatment options. Cycloastragenol (CAG) is a triterpenoid with multiple biological activities. Previously, CAG’s activity against aging-related osteoporosis was reported, but the mechanisms of actions for the activities were not understood. This study demonstrated that CAG dose-dependently inhibited osteoclast formation in receptor activator of nuclear factor-κB ligand (RANKL)-stimulated bone marrow macrophage (BMMs). Mechanism studies showed that CAG inhibited NF-κB, calcium, and nuclear factor of activated T cells 1 (NFATc1) pathways. Additionally, CAG also promoted the nuclear factor-erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)/anti-oxidative response element (ARE) pathway that scavenges reactive oxygen species (ROS). Furthermore, CAG was also found to prevent bone loss of postmenopausal osteoporosis (PMO) in a preclinical model of ovariectomized (OVX) mice. Collectively, our research confirms that CAG inhibits the formation and function of osteoclasts by regulating RANKL-induced intracellular signaling pathways, which may represent a promising alternative for the therapy of osteoclast-related disease.
Salt Stress Modulates the Landscape of Transcriptome and Alternative Splicing in Date Palm (Phoenix dactylifera L.)
Authors: Xu Zhongliang , Zhang Ning , Fu Haiquan , Wang Fuyou , Wen Mingfu , Chang Hailong , Wu Jiantao , Abdelaala Walid Badawy , Luo Qingwen , Li Yang , Li Cong , Wang Qinnan , Wang Zhen-Yu
Published: January 2022

Date palm regards as a valuable genomic resource for exploring the tolerance genes due to its ability to survive under the sever condition. Although a large number of differentiated genes were identified in date palm responding to salt stress, the genome-wide study of alternative splicing (AS) landscape under salt stress conditions remains unknown. In the current study, we identified the stress-related genes through transcriptomic analysis to characterize their function under salt. A total of 17,169 genes were differentially expressed under salt stress conditions. Gene expression analysis confirmed that the salt overly sensitive (SOS) pathway genes, such as PdSOS2;1, PdSOS2;2, PdSOS4, PdSOS5, and PdCIPK11 were involved in the regulation of salt response in date palm, which is consistent with the physiological analysis that high salinity affected the Na+/K+ homeostasis and amino acid profile of date palm resulted in the inhibition of plant growth. Interestingly, the pathway of “spliceosome” was enriched in the category of upregulation, indicating their potential role of AS in date palm response to salt stress. Expectedly, many differentially alternative splicing (DAS) events were found under salt stress conditions, and some splicing factors, such as PdRS40, PdRSZ21, PdSR45a, and PdU2Af genes were abnormally spliced under salt, suggesting that AS-related proteins might participated in regulating the salt stress pathway. Moreover, the number of differentially DAS-specific genes was gradually decreased, while the number of differentially expressed gene (DEG)-specific genes was increased with prolonged salt stress treatment, suggesting that AS and gene expression could be distinctively regulated in response to salt stress. Therefore, our study highlighted the pivotal role of AS in the regulation of salt stress and provided novel insights for enhancing the resistance to salt in date palm.
The Effect of EFL Teacher Apprehension and Teacher Burnout on Learners’ Academic Achievement
Authors: Wang Zhiping
Published: January 2022

This review aims at investigating the related studies on the role of teacher burnout and teacher apprehension in learners’ academic achievement. The negative effect of teacher burnout on learners’ academic achievement has been corroborated in the review of the literature. Furthermore, the effect of teacher apprehension on learners’ academic success has not been widely studied. However, some stressors such as having insufficient L2 knowledge, cultural differences, and classroom management problems can affect learners’ academic achievements. Finally, the pedagogical implications are illuminated for teachers, administrators, researchers, managers, teacher trainers, and counselors to decrease teacher burnout and apprehension and to develop language teaching quality in the language educational system. Some suggestions for further research are also provided to expand the current literature on teacher burnout and apprehension in English as a Foreign Language (EFL) contexts.
The Impact of COVID-19 and the Challenges of Post-COVID Rehabilitation in a Developing Country
Authors: Uddin Taslim , Rahim Hasna Raihan , Khandaker Md Nuruzzaman
Published: January 2022

The coronavirus disease 2019 (COVID-19) and its impact on human functioning are gaining increased interest. Like many other lower-income countries, the Bangladesh health and rehabilitation sector was adversely affected by COVID-19. Multiple challenges were identified for preparedness and medical rehabilitation during COVID-19 surges. Appropriate supervision of multispecialty long COVID clinics and attention to rehabilitation teamwork are important. Rehabilitation plays a key role in the management of patients with COVID-19 and can reduce the length of hospital stay and improve health outcomes. While waiting for people to be fully vaccinated; ensuring equitable access to COVID-19 vaccination, health care, and rehabilitation services among people with disabilities should be a part of the core mission during the pandemic. All levels of care including, critical, post-acute, or long covid clinic scale-up of rehabilitation services are needed. A physiatrist-led rehabilitation team approach is vital for the adaptation of rehabilitation interventions to improve the functional outcomes of persons with impairment and disability affected by COVID-19.
A Review of Electromagnetic Shielding Fabric, Wave-Absorbing Fabric and Wave-Transparent Fabric
Authors: Yin Jianjun , Ma Wensuo , Gao Zuobin , Lei Xianqing , Jia Chenhui
Published: January 2022

As the basic materials with specific properties, fabrics have been widely applied in electromagnetic (EM) wave protection and control due to their characteristics of low density, excellent mechanical properties as well as designability. According to the different mechanisms and application scenarios on EM waves, fabrics can be divided into three types: EM shielding fabric, wave-absorbing fabric and wave-transparent fabric, which have been summarized and prospected from the aspects of mechanisms and research status, and it is believed that the current research on EM wave fabrics are imperfect in theory. Therefore, in order to meet the needs of different EM properties and application conditions, the structure of fabrics will be diversified, and more and more attentions should be paid to the research on structure of fabrics that meets EM properties, which will be conductive to guiding the development and optimization of fabrics. Furthermore, the application of fabrics in EM waves will change from 2D to 3D, from single structure to multiple structures, from large to small, as well as from heavy to light.
The (Im)balance of Power. Demosthenes’ Complex Case for an Alliance with the Megalopolitans
Authors: Cross Nicholas D.
Published: January 2022

Cet article explore les motifs complexes que Démosthène 16 (Pour les Mégalopolitains) présente à l’appui d’une alliance défensive avec les Arcadiens (Mégalopolitains) en 353 av J.-C. En réexaminant tout le discours, l’article conteste que Démosthène donne la priorité à des facteurs politiques, tels que l’équilibre des puissances, et montre qu’il fait appel à divers arguments pour justifier l’interventionnisme. L’article cherche également à comprendre pourquoi les savants modernes mettent l’accent sur le rôle de l’équilibre des puissances dans ce discours, aux dépens de considérations non politiques. Ce discours fournit donc un example qui ilustre la complexité de l’ argumentation mise en oeuvre dans la diplomatie grecque classique.
ЯКІСТЬ ЖИТТЯ В КРАЇНАХ ЄС: ОСНОВНІ ТЕНДЕНЦІЇ
Authors: М. ДЄЛІНІ
Published: January 2022

В статті проаналізовано якість життя населення Європейського Союзу за різними індексами та показниками. Визначено сутність якості життя, багатогранність цієї категорії та різносторонність її складових. Проведено дослідження країн Європейського Союзу та інших країн Європи й порівняно з Україною. Досліджено основні тенденції та можливі фактори впливу на сучасний стан розвитку якості життя країн Європи.
Analisis Tekanan Pompa Ejector Dan Proses Evaporasi Dan Kondensasi Pada Fresh Water Generator Guna Memaksimalkan Produksi Air Tawar Di Kapal MV. Andhika Paramesti
Authors: Habli M. Hasan , Siregar Pande I. , Ginting Alif Rio
Published: January 2022

Pada saat kapal berlayar tanggal 26 oktober 2018 fresh water generator mengalami penurunan produksi air tawar yang menyebabkan kapasitas air tawar di kapal menurun, yang pada normalnya mampu memproduksi air tawar hingga 15 ton per hari turun menjadi 9 ton per hari. Hal ini terjadi karenakan beberapa faktor yang mengakibatkan terjadinya penurunan produksi air tawar. Lalu dilakukan analisis untuk mengetahui apa kerusakan pada fresh water generator tersebut, dan didapati kerusakan pada tekanan pada pompa ejector yang tidak normal dan proses evaporasi dan kondensasi yang tidak normal, dan juga tingkat kevakuman yang rendah.
Peranan Alat Navigasi Elektronik Berdampak Pada Keselamatan Pelayaran Diatas Kapal
Authors: Rudiana
Published: January 2022

Kapal niaga merupakan salah satu sarana moda transportasi laut yang sangat besar peranannya dalam menjaga stabilitas perekonomian dunia. Salah satu faktor untuk menjaga kelancaran, keselamatan dan keamanan operasi moda transportasi yaitu keselamatan dalam bernavigasi. Seiring dengan kemajuan teknologi komputer dan sistem informasi di bidang pelayaran telah menghadirkan Electronic Chart Display and Information System (ECDIS) sebagai cara baru dalam bernavigasi di laut yang dapat membantu meningkatkan keselamatan dalam bernavigasi, sehingga para Navigator melakukan pengawasan bernavigasi yang lebih cermat, efektif dan tepat,yang awalmya mengunakan peta laut yang menggunakan kertas peta sekarang beralih kepada system tehnologi,menggunakan electronic chart display and information system(ECDIS).

ECDIS harus selalu dalam keadaan up to date, sehingga dapat menyediakan informasi yang mampu membantu pengawasan navigasi ataupun dapat memberikan peringatan kepada Mualim jaga jika kapal akan memasuki daerah yang tidak boleh dilayari. Oleh karena itu, dibutuhkan pengetahuan para navigator yang memadai tentang alat navigasi yang akan dipakai nantinya, agar pencapaian faktor keselamatan saat bernavigasi dapat lebih optimal.

Kenyataan yang terjadi di lapangan, masih ada permasalahan dimana kapal yang telah dilengkapi dengan ECDIA tapi masih  tinggi tingkat kecelakaan kapal disebabkan alat yang dipakai masih belum familier sehingga perlu penguasaan alat baru dengan baik dalam mengoperasikan ECDIS,untuk itu perlu pembelakan bagi navigator baik itu dari maker maupun perusahaan pelayaran terhadap para navigator yang menggunakan alat ini atau ECDIS.

Tujuan penelitan ini adalah untuk melihat sejauh mana hubungan penggunaan alat navigasi terutama ECDIS digunakan diatas kapal, peneliti ingin mendapatkan bagaimana femilisasi bisa dilaksanakan diatas kapal dengan waktu terbatas, tapi pengenalan alat kepada navigator yang baru naik diatas kapal, bisa dilaksanakan.
INCIDENCE OF ABDOMINAL TUBERCULOSIS IN PATIENT PRESENTING WITH PAIN IN RIGHT ILIAC FOSSA: A PROSPECTIVE STUDY IN GRMC, GWALIOR.
Authors: Ruhela Rahul Kumar , Pipariya Prashant Raj , Kushwah Naveen , Agarwal Neeti
Published: January 2022

Introduction: Abdominal tuberculosis is sixth most common type of extrapulmonary tuberculosis. It may mimics other gastrointestinal lesions
like inammatory bowel disease, malignancies. The diagnosis is usually delayed due to non specic symptoms and signs.5-6We observed the
various presentations of abdominal tuberculosis in our hospital and analyzed the pathology in present scenario.
Aim: To evaluate the incidence of Abdominal tuberculosis in patient presenting Right iliac fossa pain and its association with pulmonary
tuberculosis and role of Anti tubercular therapy (ATT) to minimize the further complications.
Method And Materials:The study was carried out as a prospective study in the Department of General Surgery at Gajra Raja Medical College and
Jayarogya group of Hospitals, Gwalior (M.P.) for 1½ year from January 2020 to June 2021. Atotal of 50 patients with pain in right iliac fossa were
admitted and studied. The study was approved by the ethical committee of the hospital.
Results: In our study out of 50 cases with pain in right iliac fossa 15 cases were diagnosed with abdominal tuberculosis with slight female
predominance. maximum number of cases present between 20-39 years of age. 2 out of 15 had the past history of pulmonary Tuberculosis while 3
having family history of Tuberculosis. Out of 15 abdominal T.B. patients 5 patients underwent for surgery and 10 were managed conservatively &
ATT started from which 4 patients responded well to ATT and 6 developed complications and presents in emergencyemergency, Out of them 4
having SAIO, 1 having distal ileal perforation and 1 with enterocutaneous stula.
Conclusion: From the observation and result of my study most of patient Presented with chronic pain in Right iliac fossa has been diagnosed with
ileocecal TB. Study show that 40% patients respond well to ATT and 60% develop complication with symptoms of obstruction and perforation
during follow up that underwent for Surgery later on.
IMPACT OF CORONA PANDEMIC IN PEOPLE'S DAILY LIFE AND ALSO ON MENTAL HEALTH
Authors: Sankha Chatterjee , Arnab Chaudhuri
Published: January 2022

SARS –CoV-2 is not just a virus causing pandemic, but affecting whole world in a horrible way which no one has seen in their lifetime. The current
COVID-19 pandemic is prompting fear of falling sick, dying, helplessness and stigma. Urgent and timely understanding of mental health status is
needed to help the community. Our study was designed to survey the general population in India to assess the degree of psychological impact
during the pandemic.
During the early stage of second wave of outbreak, we conducted an online-based survey to collect data about participants' socio-demographic
status, concerns, psychological impact, and mental health status. We assessed the mental health status using the Hamilton Anxiety Rating Scale
(HAM-A).
Our study showed, there were gross changes in lifestyle during this pandemic period. Economically majority of the people had reduced earning or
were not earning at all. There were generalized increase in anxiety among population which were assessed both objectively using HAM-A score
and subjectively. Worry about self or family members getting infected was the most common phenomenon. Radical change in behavioral pattern
like increased faith in almighty, increased washing and cleaning behavior were noted signicantly. Sleep disturbance was another important aspect.
Spending more time on social media and nurturing hobbies was another prominent feature during this period. Following general precautionary
measures and waiting for vaccination had become the social norms.
This study conclusively suggests that we are seeing a parallel pandemic of anxiety and gross behavioral change along with covid 19 pandemic
TREATMENT OF ORAL HEMANGIOMAS USING SCLEROTHERAPY: A CONSERVATIVE APPROACH- CASE REPORT.
Authors: Amarnath Konda , Magesh Uma , Venkata Teji Apoorva , Shravani K.
Published: January 2022

Most of the vascular tumors in the maxillofacial region are hemangiomas. Hemangiomas are basically benign lesions of a vascular origin
characterized microscopically by proliferation of blood vessels. The congenital hemangioma is often present at birth and may become more
apparent throughout life. They are probably developmental rather than neoplastic in origin. They can cause esthetic and functional impairment,
depending on location. Despite their benign origin and behavior, hemangiomas in the oral cavity are always of clinical importance to the dental
profession and require appropriate clinical management as sometimes it is associated with complications like bleeding and ulceration. Treatment is
primarily dependent on correct diagnosis of the lesion and on its anatomic location. This case report presents a case of hemangioma in the
edentulous region of maxillary right molar in 47-year-old male and its treatment using sclerosing agent.
A RETROSPECTIVE OBSERVATIONAL STUDY TO ASSESS THE ROLE OF FUROSEMIDE IN PREVENTION OF BRONCHO-PULMONARY DYSPLASIA IN PRETERM INFANTS(28-32WKS).
Authors: Mishra Sankar Narayan , Nayek Kaustav , Ghosh Taraknath , Banerjee Mukut , Pal Jonaki
Published: January 2022

1. BACKGROUND OF THE STUDY: Bronchopulmonary dysplasia (BPD) is the most common pulmonary morbidity associated with
prematurity and pre- mature infants with BPD are at an increased risk of death and severe developmental disability .Despite the devastating impact
of BPD on premature infants, there are currently no therapies labeled by the US Food and Drug Administration to prevent BPD. Neonatologists
commonly use furosemide as off-label in premature infants.
2. OBJECTIVE: A. To evaluate the role of Furosemide in prevention of Bronchopulmonary Dysplasia in preterm infants.
3. METHODOLOGY: Details of total 350 babies admitted to SNCU and NICU of BMCH with gestational age between 28-32 weeksare included
in this study for last 2 years (Nov,2019—Nov 2021). The data regarding exposure to Furosemide are searched retrospectively from medical records
of the hospital.
4. RESULTS: Details of total 350 babies are taken in this study and among the total study population 47 babies died within 36 weeks of PMAof any
cause . The percentage of BPD was found to be higher in non exposed group which is 43% in comparison to exposed group With 17% and which is
statistically signicant(p-0.0028).Odds of furosemide exposure among BPD cases is less than non BPD cases.(OR=0.26).83% babies weaned off
th from oxygen/CPAP/ventilator from 7 day to 36 weeks of PMAin exposed group in comparison to non exposed group(57%).
5. CONCLUSIONS: We found that a lesser percentage of Broncho-Pulomonary Dysplasia in the babies exposed to furosemide between birth to
36 weeks of PMA in premature infants. These results provide important preliminary data to support the development of prospective studies to
evaluate the safety and efcacy of furosemide for the prevention of BPD in premature infant.
KNOWLEDGE, AWARENESS AND ATTITUDE OF DIABETIC PATIENTS TOWARDS THE ORAL FACETS ALLIED TO DIABETES MELLITUS: A SURVEY BASED STUDY
Authors: Thomas Seena , P Anuroopa.
Published: January 2022

BACKGROUND: Diabetes Mellitus has become a global epidemic, the complications of which have a signicant impact on the quality of life and
longevity of the sufferers. Oral diseases associated with diabetes mellitus include salivary dysfunction, taste dysfunction, fungal infection,
bacterial infections, poor oral wound healing, oral mucosal disease, and neuro-sensory oral disorder.Therefore, the aim of this study is to assess the
knowledge, awarenesss and attitude of diabetic patients towards the oral facets allied to type II diabetes mellitus.
METHODOLOGY: The cross-sectional questionnaire study was was administered to 100 type II diabetic patients of which 60 were males and 40
females from inpatient and outpatient department of General Medicine, Rajarjeswari Medical College and Hospital, Bangalore. Clinical
examination was done using The Community Periodontal Index of Treatment Needs (CPITN index).
RESULTS: Out of 100 subjects, 60 were males and 40 females. As per the data, only 4.4% were aware that poor oral health is associated with
diabetes The knowledge about the extra care that diabetic patients should take with their oral hygiene was also not adequate. Clinical examination
revealed a scoring of 3 and 4 indicating poor oral health.
STUDY OF CATALYTIC OXIDATION OF SERINE BY CERIUM (IV) IN PARTIALAQUEOUS ACIDIC MEDIUM.
Authors: Ghota Sonam , Dangarh B.K. , Tomar Ritu
Published: January 2022

The oxidation of serine catalysed by cerium(IV) has been studied in sulphuric acid medium at 318 K. The reaction follows rst order kinetics with
respect to [Mn(II)] while negative effect was observed for the variation of [H+] on the rate of reaction. The reaction exhibits rst to zero order
kinetics with respect to serine at its lower to higher concentrations. Under the experimental condition, the kinetically active species of cerium(IV)
has been found to be Ce(SO4)2. Activation parameters has been calculated. The mechanism has been proposed from the results of kinetic studies,
reaction stoichiometry and product analysis.
Результаты испытаний элементов мостовых сооружений из cтеклопластика после 12 лет эксплуатации
Authors: Ушаков А. Е. , Панков А. В. , Сафонов А. А. , Озеров С. Н. , Сорина Т. Г. , Цветков Д. С. , Муравьев А. Е. , Хруленко М. А. , Кленин Ю. Г.
Published: January 2022

Надёжность конструкции пешеходных мостов, изготовленных из пултрузионного стеклопластика «АпАТэК СППС», подтверждена испытаниями распорки пилона, демонтированной для исследований с вантового моста из стеклопластиковых профилей, установленного в Дубне и эксплуатирующегося с 2005 г. по настоящее время. Сделан вывод о безопасности дальнейшей эксплуатации на основании стабильности упруго-прочностных характеристик при совместном долговременном воздействии климатических и эксплуатационных факторов.
棉兰市克萨万唐人街建筑形态 Tipomorfologi Arsitektur Bangunan Pecinan Di Kesawan Medan
Authors: Rudiansyah Rudiansyah , Julina Julina
Published: January 2022

摘要当今大多数棉兰市克萨万街仍然保留着荷兰—中国建筑风格或过渡时代的建筑遗产，目前保存历史遗产的意识较少。修改建筑遗产的法律还未完善，也还未被指定为文化遗产的古建筑。这种情况使人们担心早晚将失去对原始建筑物的追踪。本文介绍棉兰唐人街建筑的形态特征。研究报告使用各种书籍和期刊进行研究。使用Andre Loeckx 和Markus Zahnd 的区域形态学理论和建筑物类型学。建筑物的总体状况并未丢失其原始形式。在重新粉刷，修复损坏的元件和更改范围内翻新功能的工作。从材料及其布局可以明显看出其形态。来自周围环境的建筑材料，例如砖，瓦屋顶和窗户。建筑物的布局位于市中心的住宅安置区，地形平坦建筑形态很适合热带及湿润气候的印度尼西亚。关键词: 形态学；建筑；唐人街；荷兰-中国；棉兰克萨万AbstrakPermukiman kesawan Medan sebagian besar masih mempertahankan arsitekturbangunan Belanda-China periode peralihan atau arsitektur Transisi, walaupun kesadaranpelestarian peninggalan bernilai sejarah masih minim. Belum ada peraturan batasanperubahan yang boleh dilakukan dan belum ditetapkan sebagai Bangunan Cagar Budaya.Keadaan ini menimbulkan kekhawatiran akan kehilangan jejak bangunan aslinya.Tulisan ini bermaksud untuk menjelaskan karakteristik tipomorfologi arsitekturbangunan pecinan di Kesawan Medan. Metode yang digunakan adalah desk researchterhadap laporan hasil penelitian, berbagai sumber buku dan jurnal. Menggunakan teorimorfologi kawasan dan tipologi bangunan dari Andre Loeckx dan Markus Zahnd.Kondisi bangunan secara umum belum kehilangan bentuk aslinya. Renovasi dilakukandalam batas pengecatan ulang, perbaikan elemen yang rusak, dan perubahan fungsi.Tipomorfologi khasnya tampak dari bahan yang digunakan dan tata letaknya. Bahan bangunan dari lingkungan sekitar, seperti bata, keramik atap genting dan jendela. Tataletak bangunan berada di kawasan emplasemen permukiman pusat kota, dengantopografi lahan datar dalam lingkungan iklim tropis basah Indonesia.Kata kunci : Tipomorfologi; Arsitektur; Pecinan; Belanda-China; KesawanMedan
Antioxidant status and selenium content in macromycetes of the Mountainous Crimea
Authors: Golubkina N. A. , Sarkina I. S. , Lapchenko V. A. , Lapchenko E. V. , Bagrikova N. A. , Naumenko T. S.
Published: January 2022

Antioxidant status and selenium accumulation by 18 macromycetes species of the Mountainous Crimea was investigated. Total antioxidant activity of 5 families’ representatives composed ranges of 23.9 - 43.3 mg GAE/g d.w. for Boletaceae, 13.0-25.0 mg GAE/g d.w. for Russulaceae, 13.5-20.9 mg GAE/g d.w. for Tricholomotaceae, 13.8-38.0 mg GAE/g d.w. for Agaricaceae. Selenium accumulation levels reached 423-3352 µg/kg d.w. (Boletaceae), 236-1076 µg/kg d.w. (Russulaceae), 664-1213 µg/kg d.w (Tricholomotaceae) and 289-2392 µg/kg d.w. (Agaricaceae). High antioxidant activity (39.2 mg GAE/g d.w.) and specific carotenoid composition including 9-cis lycopene (1.8 mg/g) and beta-carotene (0.2 mg/g) were recorded for Clathrus ruber for the first time. The results indicate high significance of macromycetes investigated as powerful sources of antioxidants and selenium.
ПОВСЕДНЕВНАЯ ЖИЗНЬ ЖИТЕЛЕЙ СЕЛА ПРОЛЕТАРСКОЕ В 2000-2005 гг.
Authors: Хамзатова З.Р. , Радаева Х.А.
Published: January 2022

Произошедшие масштабные перемены в Чеченской Республике, связанные с кризисом и вооруженным конфликтом в конце ХХ - начале ХХ1 вв., привнесли изменения не только в общественное сознание, но и в повседневную жизнь её жителей. Интерес к периоду 2000-2005 гг. объясняется и тем фактом, что население Республики, как городское, так и сельское, преодолевая серьезные трудности, переходило от войны и насилия к миру.
РОЛЬ ДИНАСТИИ ОКОЦКИХ В УСТАНОВЛЕНИИ ПОЛИТИЧЕСКИХ СВЯЗЕЙ С РОССИЕЙ
Authors: Гелаева З.А. , Абдулвахабова Б.Б.-А.
Published: January 2022

В статье раскрывается роль династии Окоцких в установлении политических связей с Россией, становлении и развитии добрососедских, дружественных отношений в конце XVI – начале XVII века. В середине XVI в. с присоединением Астраханского ханства Россия вышла к кавказским границам, и с этого времени кавказское направление заняло ведущее место в восточной политике царского правительства. В XVI веке Кавказ становится главным объектом в противостоянии трёх империй: России, Турции и Ирана. Именно в этих условиях и закладываются основы русско-чеченских отношений. Россия не желала, чтобы Кавказ превратился в антироссийский плацдарм.
A STUDY TO ASSESS THE KNOWLEDGE REGARDING VACCINE PREVENTABLE DISEASES AMONG THE MOTHERS OF UNDER FIVE CHILDREN AT RURAL AREA OF JAIPUR DISTRICT WITH VIEW TO DEVELOP AN INFORMATION BOOKLET
Authors: Vishnu Kumar  , Suresh
Published: January 2022

INTRODUCTION: Children are the world’s most valuable assets and their wellbeing indicates the standard of living of the country. They constitute one third of the total population. It has been noticed that almost one out of every five live born infants die before reaching 5 years of age. Immunisation is one of the most important weapons for protecting individuals and the community from serious diseases. The Department’s immunisation team supports the public and health professionals by offering clear, evidence-based information about different diseases, the possible side effects of immunization and available vaccines.
AIM OF THE STUDY: Assess the knowledge regarding vaccine preventable disease among mothers of under five children.
METERIAL AND METHOD: A descriptive study was carried out to assess the knowledge of 60 mothers selected by purposive sampling, were assessed by using a structured knowledge questionnaire and analyzed by using descriptive and inferential statistics were used for data analysis.
RESULT: The findings of the study reveals that to the level of knowledge shows that majority of 60 mothers of under five children in which (33) 55% had below average knowledge, (18) 30% had average knowledge and (9) 15% of them had above average knowledge regarding vaccine preventable diseases.
CONCLUSION: It can be concluded that mothers have below average knowledge regarding vaccine preventable diseases as per current research recommendations. They require education and to enhance their knowledge regarding vaccine preventable diseases. Self-information booklets were distributed to them to improve the knowledge regarding vaccine preventable diseases
KEY WORDS: Awareness, knowledge, mothers, vaccine, information booklet.
Penerapan Metode Diskusi Kelompok untuk Meningkatkan Minat Belajar Siswa di MI Darul Ulum Genengan
Authors: Sriati Yuana Indah , Ningsih Ajeng Nurya Tri , Sofiandira Vegi Teria , Fauzi Adin
Published: January 2022

Referring to the Instruction of the Minister of Home Affairs Number 38 of 2021 which explains, for regions that have entered levels 1 to 3 in the Covid-19 distribution map, they can open limited face-to-face learning. In response to this, many schools in Blitar Regency have implemented limited face-to-face learning, one of which is MI Darul Ulum Genengan. Besides, one of the problems that will likely occur when face-to-face learning is carried out is the lack of interest in learning when the lesson takes place. This is because students have been doing online learning at home for a long time, and when they have to return to school, there will certainly be many differences, such as the way the material is delivered and the material obtained. Therefore, the activities we carry out are aimed at helping students increase their interest in learning in class, by using the Group Discussion method. The results of this activity indicate that students are more motivated by conducting group discussions, they are more enthusiastic when studying or working with their friends, and students become more creative. It is hoped that later this activity can be followed up by teachers at MI Darul Ulum to increase interest in learning and can provide motivation during class learning.
Baliklio vonios veiksmingumas vidutinio sunkumo ir sunkaus atopinio dermatito simptomams lengvinti. Atvejo-kontrolės tyrimų apžvalga
Authors: Ponelytė Inesa , Šmigelskytė Melinda , Valiukevičienė Skaidra
Published: January 2022

Atopinis dermatitas (AD) yra dažna lėtinė uždegiminė odos liga, kuria serga 10–20  proc. vaikų ir 2–5 proc. suaugusiųjų. Ligai būdingi dažni paūmėjimai, antrinė S. aureus infekcija, kuriai gydyti skiriami antibiotikai didina bakterijų atsparumą. Todėl, siekiant kontroliuoti odos infekciją, sergantiesiems AD, taikomos baliklio vonios. Darbo tikslas. Atlikti literatūros apžvalgą ir nustatyti 0,005 proc. natrio hipochlorito vonių veiksmingumą vidutinio sunkumo ir sunkaus AD simptomų kontrolei. Medžiaga ir metodai. Literatūros apžvalga rengta remiantis PRISMA rekomendacijomis. Mokslinių straipsnių paieška vykdyta elektroninėje duomenų bazėje „PubMed“, naudojant raktinius paieškos žodžius: „atopic dermatitis“, „atopic eczema“, „bleach baths“ and „sodium hypochlorite baths“. Remiantis įtraukimo ir atmetimo kriterijais, į literatūros apžvalgą įtraukti penki atvejo-kontrolės tyrimai. Rezultatai. Dviejuose tyrimuose po natrio hipochlorito vonių pacientams nustatytas statistiškai reikšmingai didesnis AD skalės EASI (angl. Eczema Area and Severity Index) balų sumažėjimas, lyginant su placebo. Viename tyrime nustatyta, jog vandens vonios veiksmingesnės nei baliklio vonios, siekiant sumažinti SCORAD (angl. SCORing Atopic Dermatitis) balus ir AD simptomus. Kito tyrimo rezultatai rodo, jog natrio hipochlorito vonios ir gydymas flutikazono propionato kremu nėra veiksmingesni nei flutikazono propionato kremo terapija AD kontrolei. Išvados. Tyrimų rezultatų duomenys, vertinant baliklio vonių veiksmingumą AD gydyti, prieštaringi. Remiantis tyrimų rezultatais, 0,005 proc. natrio hipochlorito vonios nepažeidžia odos barjerinės funkcijos, yra gerai toleruojamos ir saugios.
Some problem situation of the initial stage of the judicial procedure and ways of their solution
Authors: Miroshnichenko Yurii
Published: January 2022

The article is a presentation of some results of the author's research on the problems of methodological and forensic support of court proceedings. It emphasizes the importance of creating a basic judicial methodic, which would be the starting point for the formation of methods of judicial review of criminal cases of certain categories. The author's definition of the basic judicial methodic is given. Recommendations are given for resolving typical situations of the initial stage of court proceedings, which include the periods before, during and after the preparatory court hearing. Situations of non-appearance of court participants in court proceedings are considered; complications related to the refusal of defendants in custody to go to the courtroom, the need to suspension the proceedings, the association (separation) of criminal cases, acquaintance with the materials of the pre-trial investigation of persons who entered at this stage of criminal proceedings.

Summing up, the author notes that the activities of the court in criminal proceedings consist of successive intellectual and volitional operations for the adoption and realization of various procedural decisions. A procedural decision is an imperious expression of the judge's will on legal issues that arise during the proceedings. Procedural decisions, due to the need to resolve some problematic situations of the initial stage of court proceedings, are closely related to tactical decisions. In many cases, the tactical decision precedes the procedural one, which in this case becomes an element of the system of its implementation. A tactical decision is a choice of the optimal and admissible means (procedural action, reception, operation) based on the analysis of the current situation, the purpose of which is to create favorable conditions for court proceedings by purposefully influencing one or another object. The tactical task of the preparatory court proceedings is to reduce the level of information uncertainty about the final investigative and initial judicial situation, the methods of implementation of which will be discussed in the next article of the author.

Keywords: criminalistics methodics, methodic of court proceedings.