bluuebunny/crossref_metadata_2025 huggingface dataset:
Theory of chaos synchronization and quasi-period synchronization of an all optic 2n-D LAN
Authors: Senlin Yan
Published: August 2021

Theory of chaos synchronization and quasi-period synchronization of an all optics local area network (O-LAN) is deeply studied and discussed, where two coupled-lasers are used as network’s double-star and the other single-lasers are used as network nodes. The LAN operates double-star lasers to drive node lasers in two links to perform a 2n−D (n is a positive integer, dimensions (D)) laser network. The O-LAN has the characteristics of an all optics LAN with double-center and two link nodes. Our theoretical and numerical results prove that the double-center lasers can obtain their synchronizations with each laser in two link nodes. A route to chaos after a quasi-period bifurcation is analyzed to illustrate dynamics distribution region of O-LAN. We find five quasi-period regions, four chaos regions, where there is a region where instability mixes with the first chaos, and a stable region. We find also that O-LAN can obtain its parallel multi-dynamics synchronizations, such as cycle-one synchronization, cycle-2 synchronization, cycle-3 synchronization, cycle-4 synchronization, cycle-5 synchronization, other quasi-period synchronization and chaos synchronization, shown in two links of O-LAN by shifting the currents of the lasers in one link. The theory of all optics LAN and its obtained results are useful to study on complex dynamic system, optics network, artificial intelligence, chaos and its synchronization.
The Concept of State in Kierkegaard’s Papers
Authors: Wende Matías Tapia
Published: August 2021

In this paper, I aim to show the evolution of Kierkegaard’s views on the state scattered in his Papers. To do this, I will carry out an analysis divided into chronological periods, and I will characterize each period in terms of its main features. The goal is to give a comprehensive account of Kierkegaard as a champion of the monarchical and authoritative state, who loses his patience and attacks the established order only when he thinks that Christianity’s truth is at the greatest risk. This interpretation contrasts both with a mere despotic Kierkegaard and with a more liberal one.
The Liberating Cacophony of Feelings: Kierkegaard on Emotions
Authors: Rosfort René
Published: August 2021

This article argues that Kierkegaard’s account of emotions has something important to contribute to contemporary philosophy of emotions. The argument proceeds in five steps. The first section starts by outlining two influential paradigms in contemporary philosophy of emotions: the feeling theories and the cognitive theories. The second section then turns to a critique of two prominent approaches that read Kierkegaard’s conception of emotions as belonging to the cognitive theories. The third section presents Kierkegaard as a phenomenologist of emotional ambiguity, while the fourth section attempts to outline a taxonomy of Kierkegaard’s phenomenology of emotional experience. The fifth and final section argues that Kierkegaard’s primary contribution to contemporary philosophy of emotions is to be found in his concept of anxiety as the experience of human freedom particularly with respect to the ambiguity of feeling and understanding characteristic of this fundamental affective phenomenon.
The (Im)proper Community: On the Concept of Eiendommelighed in Kierkegaard
Authors: Lysemose Kasper
Published: August 2021

The aim of the paper is to demonstrate that the concept of Eiendommelighed in Kierkegaard has a considerable philosophical weight, although it figures only marginally. It is emphasized that Kierkegaard—well ahead of the deconstruction of community in contemporary philosophy—creates a concept by which the complicity of singularity and community becomes evident. The gist of the concept is an indistinction between the proper and the improper. Eiendommelighed is that by which singularities, or neighbors, are called into the inappropriability of their ownmost being. This call is then recalled between neighbors who in this way form an (im)proper community.
Lukács and Kierkegaard: Decadence or Despair
Authors: Hannay Alastair
Published: August 2021

A distrust of focus on subjectivity and the individual provoked by his meeting with Sartrean existentialism led György Lukács to turn his early but qualified admiration of Søren Kierkegaard into an accusation of fostering a bourgeois culture of the kind Kierkegaard is usually thought to have opposed. Not every Marxian thinker has been equally wary of subjectivity, but all have found in Kierkegaard a crucial absence of concern for human exploitation within a context of natural scarcity. However, a more measured reading suggests a case for resolving the need to choose between Lukács’s insistence on “spirit” as a collective notion and Kierkegaard’s as cultivation of a trans-historically oriented, self-stabilizing social will.
„Die Grundlagen der Lehre der Russischen Orthodoxen Kirche über Würde, Freiheit und Rechte des Menschen“ (2008). Eine Debatte
Authors: Wasmuth Jennifer
Published: August 2021

In dem Beitrag werden das 2008 von der Bischofssynode der Russischen Orthodoxen Kirche verabschiedete Dokument „Die Grundlagen der Lehre der Russischen Orthodoxen Kirche über Würde, Freiheit und Rechte des Menschen“ sowie die darauf erfolgende Antwort der Gemeinschaft Evangelischer Kirchen in Europa in ihren wesentlichen inhaltlichen Aussagen vorgestellt und die sich aus beiden Dokumenten ergebende kirchliche wie wissenschaftliche Debatte skizziert.
Die Russische Orthodoxe Kirche und die Menschenrechte – Beobachtungen zum Hintergrund ihrer Position
Authors: Kadotschnikow Ernest
Published: August 2021

In den Stellungnahmen von Vertretern der Russischen Orthodoxen Kirche zu den Menschenrechten finden sich ambivalente Aussagen, die eher in Richtung von Befremden und Kritik tendieren. Die Menschenrechte sind demnach ein Konzept des häretischen, aufgeklärten und somit gottlosen Westens, das den Menschen anstelle von Gott in den Mittelpunkt stellt und die Rechte der Gemeinschaft gegenüber dem Individuum sowie die traditionelle Familie gefährdet. Vertreter der Russischen Orthodoxen Kirche berufen sich jedoch auf die Menschenrechte, wenn sie glauben, dass die Kirche davon profitiert. Dieser Artikel beleuchtet die Hintergründe, weshalb sie häufig keinen Anlass sehen, die für die Kirche positiven Seiten der Menschenrechte zu erkennen.
Ökumenische und politische Konvergenzen in Bezug auf die Menschenrechte
Authors: Hallensleben Barbara
Published: August 2021

Das Dokument der Russischen Orthodoxen Kirche über „Würde, Freiheit und Rechte des Menschen“ (2008) löste eine eher polemische Debatte aus. Der kürzlich durch das Ökumenische Patriarchat von Konstantinopel approbierte Text „Für das Leben der Welt. Auf dem Weg zu einem Sozialethos der Orthodoxen Kirche“ (2020) wirft neues Licht auf die damalige Auseinandersetzung und eröffnet Perspektiven einer ökumenischen Konvergenz über die Menschenrechte.
Prognostic value of microRNA-4521 in non-small cell lung cancer and its regulatory effect on tumor progression
Authors: Sun Butong , Cong Dan , Chen Kang , Bai Yuansong , Li Jun
Published: August 2021

Background

Non-small cell lung cancer (NSCLC) is a malignant tumor with the highest mortality rate in our country. It has been found in many studies that microRNA-4521 (miR-4521) is abnormally expressed and plays a role in clear cell renal cell carcinoma and other cancers.

Objective

The purpose of this study was to explore the relationship between miR-4521 expression and clinical prognosis, as well as its influence on cell biological behavior.

Methods

The expression differences of miR-4521 in NSCLC tissues and cells were examined by qRT-PCR technology. Kaplan–Meier survival analysis and Cox regression analysis were used to analyze the clinical information and survival status of patients to explore the relationship. Using the vitro cell MTT assay, Transwell assay, and western-blot analysis, the effects of miR-4521 on cell proliferation, migration, and invasion were analyzed.

Results

The expression of miR-4521 in NSCLC tissues and cells was significantly downregulated. miR-4521 can be used as an independent prognostic factor. The survival rate of the miR-4521 low expression group was lower, which was significantly related to poor prognosis. In addition, the low expression of miR-4521 significantly promoted cell proliferation, migration, and invasion with highly expressed related protein levels. FOXM1 might be a direct target of miR-4521.

Conclusion

The results of this study showed that the low expression of miR-4521 indicated the poor prognosis of NSCLC and promoted cell proliferation, migration, and invasion by targeting FOXM1.
Small cell lung cancer transformation during antitumor therapies: A systematic review
Authors: Chai Xing , Zhang Xinru , Li Wenqian , Chai Jin
Published: August 2021

Lung cancer is the most common cause of cancer-related death. Non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) are the two major histological categories of lung cancers. Drug resistance is a great challenge for cancer treatment, and histological transformation from NSCLC to SCLC is one of the mechanisms underlying drug resistance in NSCLC patients. SCLC-transformed patients show combined characteristics of NSCLC and SCLC; however, they lack timely diagnoses and effective treatment strategies. Thus, we reviewed the clinical characteristics of SCLC transformation patients with a literature search to enhance clinical consciousness, diagnosis, and personalized treatment for patients with it.
Tribological properties of organotin compound modified UHMWPE
Authors: Yang Tian , Xu Haiping , Jin Yongliang , Huang Ke , Tu Jiesong , Jia Dan , Zhan Shengpeng , Ma Lixin , Duan Haitao
Published: August 2021

A range of ultra-high molecular weight polyethylene (UHMWPE)/tetraphenyltin (Ph4Sn) nanocomposites were fabricated by hot-pressing. The surface hardness and crystallinity of composites were studied. It revealed that the surface hardness of the composites decreased slightly, and the changing trend of crystallinity was consistent with the hardness. The tribological properties of composites under seawater lubricating conditions were investigated. The experimental results showed that the friction coefficients of the composites almost keep the same but the wear reduced sharply. With the increases of Ph4Sn content, the wear of composites first decreases significantly and then increases, meanwhile the friction coefficient remains basically unchanged. The dominant wear mechanism has changed from adhesive wear to plastic deformation and finally to abrasive wear. The addition of Ph4Sn particles reduces the sensitivity of the Ph4Sn/UHMWPE composites to water and transfers the load to the UHMWPE network, resulting in the wear resistance improved.
Reglementierte Berufe: Einordnung der Länderempfehlungen der Europäischen Kommission zum Reformbedarf des Regulierungsrahmens in Deutschland
Authors: Recker Clemens
Published: August 2021

In its country-specific recommendations for Germany, the European Commission regularly calls for reform in the area of regulated professions. These reform demands focus in particular on the business-related services provided by lawyers, tax advisors, auditors, architects or civil engineers. In doing so, the Commission pursues the thesis that the protection of similar general interests in the case of the domestic regulatory approach with binding professional access rules and a mandatory chamber system is accompanied by a comparatively high regulatory intensity and unnecessarily restricts competition. The Commission bases this assumption on different direct and indirect regulatory and competition indicators. This paper provides an overview of the strengths and weaknesses of these indicators and concludes that these do not allow for a robust conclusion on below-average competition intensity in professional services in Germany.
Functional capacity: association with risk for falls, fear of falling and pain in the elderly
Authors: Nadu Alexandre de Andrade , Sala Danila Cristina Paquier , Silva Carla de Lima , Monteiro Odete de Oliveira , Costa Paula Cristina Pereira da , Okuno Meiry Fernanda Pinto
Published: August 2021

Objective: to associate functional capacity with the risk of falls, fear of falling, and pain in hospitalized elderly. Methods: cross-sectional study with 130 elderlies. The following scales were applied: Activities of Daily Living, Instrumental Activities of Daily Living, Morse Falls, Fear of Falling and Pain. The Kruskal-Wallis test was used to associate the categorical variables to the Daily Living Activities and Pain Scales and the Chi-square test to the Morse Falls. Spearman’s Correlation Coefficient was used to associate the continuous variables with the Fear of Falling Scale. Results: most of the elderlies were independent for basic and instrumental activities of daily living, had high risk for falls, little concern about the possibility of falling, and no pain. Those with higher risk for falls are those with more dependence and have more concern about falling. Conclusion: there was an association between functional capacity and the scales fear of falling and pain.
Attitudes of professionals from Psychosocial Care Centers towards alcohol, alcoholism, and alcoholics
Authors: Prates José Gilberto , Oliveira Márcia Aparecida Ferreira de , Claro Heloísa Garcia , Pinho Paula Hayasi , Boska Gabriella de Andrade , Fernandes Ivan Filipe de Almeida Lopes , Silva Julia Carolina de Mattos Cerioni
Published: August 2021

Objective: to assess the attitudes of professionals from Psychosocial Care Centers towards alcohol, alcoholism, and alcoholics. Methods: a cross-sectional evaluation study with 288 professionals from 12 healthcare services. Sociodemographic data, Patient Satisfaction Scale with Mental Health Services and Attitude Scale for alcohol, alcoholism, and alcoholics were collected. Results: the professionals who showed a more critical attitude towards their work routine and those who worked in the healthcare services for longer had positive attitudes towards alcohol, alcoholism, and alcoholics. Professionals from the administrative team and health technicians had more negative attitudes. Conclusion: the attitudes of professionals towards alcohol, alcoholism, and alcoholics, in general, are positive and were associated with longer working time in the field and the manifestation of disapproving situations with work.
La delimitación de la libertad contractual en virtud de exigencias sociales
Authors: Acosta Rodríguez Joaquín Emilio , Gual Acosta José Manuel
Published: August 2021

En este artículo se presenta el impacto que los movimientos sociales de la segunda mitad del siglo XIX tuvieron en la doctrina de contratos del siglo XX. Se propone un análisis de esta influencia para reformular el problema de la libertad contractual, a la luz del Estado social de derecho, y el correlativo redimensionamiento del orden público y las buenas costumbres. Además, se recurre a un análisis histórico-originalista para repensar la fuerza obligatoria del contrato.
De los derechos de los grupos indígenas en el marco internacional
Authors: Herrán Pinzón Omar Antonio , Blanco Blanco Jacqueline
Published: August 2021

A partir de un método de investigación histórico, se realiza un recorrido legislativo por el derecho de los indígenas en el campo internacional, contenido en el reconocimiento de la diversidad sociocultural y el posible conflicto que conlleva esta realidad aprendida constitucionalmente. Se discute la importancia de la diversidad sociocultural de las comunidades indígenas y su cosmovisión frente a prácticas que atentan contra la dignidad humana ―como la mutilación genital femenina―, que concentran los intereses actuales de la comunidad internacional.
Narrativas de la violencia de género en estudiantes de la Universidad Libre, Seccional Bogotá: conceptos, actitudes y prácticas sociales
Authors: Mazuera Ayala Andrea , Mazuera Ayala Paula , Mahecha Sánchez Gloria Andrea
Published: August 2021

El género representa actualmente un reto de inclusión educativa en el contexto universitario. El presente artículo busca caracterizar los conceptos, actitudes y prácticas sociales relacionados con la violencia de género de los estudiantes del programa de Derecho de la Universidad Libre, en el marco de la asignatura Lectura Crítica. Desde las categorías principales se identifican subcategorías que dan cuenta de conceptos que transitan entre el sentido común y lo normativo jurídico, actitudes que se apoyan en las experiencias propias, así como en la proyección en el otro. Por último, desde las prácticas sociales, se identifica una tendencia a actuar y tomar partido ante estas situaciones.
La migración venezolana y sus consecuencias desde la óptica coaccionada de los medios de comunicación
Authors: Mancera Ardila Edisson Alexander
Published: August 2021

Con el propósito de analizar la responsabilidad de los medios de comunicación sobre la información y las opiniones que transmiten, se estudian teorías del poder y textos legales que establecen los límites y las obligaciones que recaen sobre estos. A partir de este análisis se constata que los migrantes venezolanos son víctimas de todo tipo de discriminación mediática, que atenta contra sus derechos fundamentales, principalmente contra la dignidad humana.
La innovación en el aula universitaria a través de la realidad aumentada. Análisis desde la perspectiva del estudiantado español y latinoamericano
Authors: Cabero-Almenara Julio , Vázquez-Cano Esteban , Villota-Oyarvide Wellington Remigio , López-Meneses Eloy
Published: August 2021

Objetivo. Este artículo analiza las experiencias de innovación universitaria con tecnologías inmersivas (realidad aumentada, RA) de diversas titulaciones de la Universidad Pablo de Olavide de Sevilla (España) y de la Universidad Católica de Santiago de Guayaquil (Ecuador) correspondiente al curso académico 2018-2019. Metodología. A través de una metodología mixta de análisis de datos (cuantitativa y cualitativa) y el diseño de un cuestionario ad hoc de elaboración propia se analizaron las percepciones de 202 estudiantes en relación con las ventajas y desventajas de la RA y las apps de realidad aumentada utilizadas en los seminarios de Tecnologías Emergentes en contextos educativos, impartidos en ambas universidades. Resultados. Los resultados muestran que las aplicaciones móviles más valoradas fueron: QuiverVisión y Hp Revail por su interactividad, entorno usable y su proyección didáctica en contextos formativos, especialmente en edades tempranas. Conclusiones. El estudiantado percibe, como principales ventajas de la RA, el desarrollo de habilidades cognitivas y competenciales y, como principales desventajas, la necesidad de formación del profesorado universitario para la implementación en las aulas y los posibles efectos adversos de la brecha digital.
El modelo para la capacitación de docentes en el sector de educación para personas sobredotadas, una investigación en América Latina
Authors: Almazán-Anaya Andrew , Almazán-Anaya Dafne
Published: August 2021

Introducción. La educación del estudiantado sobredotado en América Latina todavía está en desarrollo, lo que incluye el proceso de capacitación de su profesorado, un aspecto clave en el éxito de las escuelas especializadas. Objetivo. Realizar un estudio que describiera y analizara el proceso de capacitación del personal docente para estudiantado sobredotado en tres de las escuelas diferenciadas (especializadas) más grandes de América Latina, con la finalidad de desarrollar una guía que reuna las experiencias en un plan general de capacitación. Metodología. La metodología fue cualitativa con entrevistas y observación de campo por cuatro años, en la que desarrollamos, a modo descriptivo, una guía por cada paso de la capaictación, basado en member checking, triangulación, verificación y cotejo con la bibliografía existente. Resultados, se describieron seis etapas de la formación del profesorado, lo que resultó en la obtención de un panorama general de cómo el profesorado de las escuelas especializadas en talento se capacitan en un país en desarrollo, donde los procesos formales y acreditados de formación docente aún no se han implementado completamente. Estos hallazgos mostraron fortalezas y debilidades en las etapas formativas de docentes en este ambiente especial que permiten mantener en funcionamiento centros educativos especiales de alumnado sobredotado en escuelas de América Latina, y creó una guía basada en la evidencia para la formación de futuros grupos de docentes en escuelas con estudiantes sobresalientes, especialmente cuando no hay un proceso de capacitación formal disponible en la localidad.
El aprendizaje organizacional en instituciones de educación superior. Caso de estudio de un grupo de investigación
Authors: Rodriguez-Lora Vanessa , Herrera-Caballero Juan Manuel
Published: August 2021

Introducción. El conocimiento es considerado hoy en día como uno de los factores más importantes en las organizaciones, ya que este permite que estas reaccionen a los cambios de entorno, pues el establecer flujos al interior de ellas les permite ser más competitivas e innovadoras. Pero qué pasa cuando ese conocimiento se encuentra en una institución de educación, en la cual, a pesar de ser considerado su activo más importante, no se establecen las redes de conocimiento apropiadas para que estas estén en capacidad de responder a estos cambios, y se impide desarrollar procesos de transferencia tanto interna como externa. Este artículo es derivado de la tesis doctoral denominada Aprendizaje organizacional como mecanismo de transferencia de conocimiento en las instituciones de educación superior. Objetivo. Mostrar como los grupos de investigación universitarios se comportan como organizaciones que aprenden y busca identificar los factores que permitían desarrollar el aprendizaje. Metodología. Para ello, se diseñó un estudio de corte cualitativo, del tipo descriptivo-evaluativo, no experimental, de una sola medición, en la cual se empleó una triangulación de instrumentos que permitan corroborar y dar validez a los hallazgos a través del uso de herramientas como entrevistas, encuestas, observación participante y análisis de redes sociales. Resultados. Los resultados obtenidos fueron analizados con herramientas especializadas para datos cualitativos tales como MaxQDA y Ucinet en métodos de investigación mixtos. Conclusiones. El estudio permitió identificar cómo las instituciones de educación y, en particular, los grupos de investigación se comportan como organizaciones que aprenden y conforman redes de interacciones sociales que establecen diferentes tipos de flujos entre ellas.
Actitudes de estudiantes de una universidad pública sobre la aplicación del aprendizaje invertido
Authors: Chambi-Mescco Edith
Published: August 2021

El enfoque denominado aprendizaje invertido ha estado llamando la atención del personal docente en los últimos años, debido a su novedosa forma de programar y ejecutar las sesiones de aprendizaje, lo que ha marcado una diferencia con el modelo tradicional. Se ha aplicado este enfoque en diversos programas de educación superior, los resultados expresan los logros que se han obtenido en términos de aprendizaje. El objetivo del presente artículo de investigación es identificar las actitudes que tiene el estudiantado de segundo ciclo de estudios generales de una universidad pública peruana, luego de haber experimentado el aprendizaje invertido en la asignatura de Lenguaje y Comunicación, en el semestre académico 2018-II. Este estudio es cuasiexperimental y de enfoque mixto. Se aplicó un cuestionario, elaborado por Farrah y Qawasmeh (2018), para recoger las actitudes de 70 estudiantes de dos aulas y que llevaron el curso dirigido por el mismo docente. Los resultados indican que el estudiantado considera que el enfoque pedagógico aprendizaje invertido es altamente beneficioso para sus aprendizajes y sugieren que su eficacia depende de la autonomía que tenga el estudiantado para desarrollar las actividades previas y de las facilidades que tengan para acceder a internet.
Kinetic study on iso-concentration hydrogen peroxide bleaching of poplar chemi-thermomechanical pulp by the process of continuous chemical supplement
Authors: Sun Xianqi , Hou Qingxi , Shi Haizhen , Zhou Lichun
Published: August 2021

In the authors’ previous studies, a bleaching process based on continuous chemical supplementation (CCS) was proposed to improve the effectiveness of peroxide bleaching of chemi-thermomechanical pulp (CTMP). In this study, the kinetic model of the CCS process of peroxide bleaching was applied to poplar CTMP to explore how the bleaching rate was affected. The model was based on the rate of chromophore elimination characterized by the brightness gains of bleached pulp. The reaction rate of chromophore destruction proceeded via a rapid initial phase followed by a slow phase. The equation of reaction rate was confirmed. The value of reaction order was -3.62, and the activation energy was 288.8 kJ/mol. The developed kinetic model was a good fit for the experimental results.
Furan resin as potential substitute for phenol-formaldehyde resin in plywood manufacturing
Authors: Varodi Anca Maria , Beldean Emanuela , Timar Maria Cristina
Published: August 2021

Replacement of phenol-formaldehyde with a mixed furan resin is considered in this work as a means to improving plywood properties made with urea-formaldehyde-based adhesive currently made with an addition of phenol-formaldehyde resin. Previous research showed that the furan resins can improve water resistance and can provide long stability for the glue line. Plywood was manufactured with modified adhesives and characterized in comparison with a reference product. Thickness, physical properties (moisture content, density, and total water absorption), mechanical properties (shearing strength, bending strength, and elasticity modulus in bending), and formaldehyde emission were determined according to standardized methods. The results indicated that the addition of furan resin enhanced the water resistance by 43% and formaldehyde emission is according to E1 class. Also, the mechanical properties were improved; the shear strength for the adhesive composition with furan resin was increased by 14 to 30% compared with the reference product, depending on the testing conditions.
Identification of some fiber characteristics in Rosa sp. and Nerium oleander L. wood grown under different ecological conditions
Authors: Yigit Nurcan , Mutevelli Zuhal , Sevik Hakan , Onat Saadettin Murat , Ozel Halil Baris , Cetin Mehmet , Olgun Cagri
Published: August 2021

Climate-dependent changes in wood anatomical characteristics were studied for Rosa sp. and Nerium oleander sp. grown in phytosociological areas. For this purpose, wood samples were taken from the individual wood species grown in Antalya, Eskisehir, and Kastamonu provenances, where Terrestrial, Black Sea, and Mediterranean climate types prevail, and 11 anatomical characters were identified or calculated. As a result of the study, it has been determined that the climate has large effects on the characteristics that are the subject of the study and that each characteristic is at a higher level in individuals grown in areas where different climate types prevail. The highest values in Rosa species were obtained in the individuals grown under Terrestrial climate type in all characteristics except for LW (lumen widths), EC (elasticity coefficients), and FF (F-Factors.) Whereas in Nerium oleander, the highest values were obtained in individuals grown in the Mediterranean climate type in FL (fibre lengths), LW (lumen widths), FR (felting ratios), and EC (elasticity coefficients). For the same species type, in the Terrestrial climate, RIJID (rigidity coefficients), MUHT (Muhlstep ratios), and RUNK (Runkel ratios), and in the Black Sea climate DWT (double wall thicknesses) and WT (wall thicknesses) characteristics had high values.
A handy skin wound dressing prepared by alginate and cationic nanofibrillated cellulose derived from solid residues of herbs
Authors: Jiang Ting , Feng Xiaoyan , Xu Rui , Dong Sheng , Wu Meiyan , Zheng Xin , Lu Weimin , Li Bin
Published: August 2021

Large amounts of solid residues are generated after extraction of active ingredients from herbs for the production of natural medicine, but the residues have not been well utilized. In this work, cationic nanofibrillated cellulose (CCNF) was prepared from the solid residues of Astragali Radix by etherification and homogenization. The CCNF was mixed with sodium alginate (SA) to create a hydrogel dressing by physical interactions between CCNF and SA without any addition of cross-linker. The CCNF-SA dressing exhibited moderate viscosity, good moisture-maintaining property, great antibacterial activities, good cytocompatibility, and clear acceleration of wound healing on rats. Furthermore, this CCNF-SA dressing with nanofibrous structure had moderate air permeability. Therefore, the CCNF-SA hydrogel could be used potentially as a skin wound dressing. Development of cost-effective and bioactive wound dressing materials is of crucial importance to reduce the burden on patients and healthcare systems. Also, this work provides a new strategy for valorization of the solid residues of herbs.
Management accounting and control system in the u-model internationalization process. A case study
Authors: M Roque Ana Filipa , Céu Alves Maria do , Raposo Mário Lino
Published: August 2021

This study examines the role of management accounting and management control systems (macs) in the successful implementation of the Uppsala Internationalization Model (U-Model) and in the improvement of firms’ performance. To achieve this, and after a broad literature review, a case study was conducted. Using a dynamic and “inside-out” approach, data was collected through interviews and documental analysis. The internationalization model (im) of a company and the relationship between macs and its internationalization strategy (U-Model) were analyzed. This study emphasizes the existence of several roles (passive and active) of macs and highlights the fact that these systems are used throughout the internationalization process (ip) in differentiated ways. As far as we know, it is the first time the relationship between macs and a specific internationalization model (U-Model) has been studied. This research helps to increase knowledge in practice, as it helps companies understand how they can adjust their macs according to their U-Model development phase. Given the growing interest in internationalization, we hope to contribute to improving the knowledge on the relationship between macs and the ip and its effects on companies’ performance. This study points to promising results that justify further studies of this relationship.
Planteamiento estratégico para la financiación inclusiva del turismo por parte de los organismos financieros internacionales
Authors: Carrillo Hidalgo Isabel , Pulido Juan Ignacio
Published: August 2021

Los organismos financieros internacionales financian el turismo para la consecución de sus objetivos de desarrollo económico y reducción de la pobreza; además, entienden la inclusión financiera como parte de su política de actuación. Sin embargo, los estudios realizados hasta ahora muestran que la financiación al turismo realizada por estos organismos no favorece a la inclusión financiera de la población y que carecen de un planteamiento estratégico común en este sentido. Ello justifica la necesidad de plantear la posibilidad de establecer una estrategia que guíe la política a seguir por estos en la financiación del turismo, de modo que su actuación sea lo más financieramente incluyente posible. El objetivo de este trabajo es exponer los resultados del proceso de elaboración de este planteamiento estratégico, llevado a cabo a partir de una revisión bibliográfica previa y un cuestionario realizado a un panel de diez expertos internacionales. Este planteamiento establece la importancia de los procesos de adjudicación, la sensibilización en la materia, los sistemas de control y el apoyo no financiero.
Análisis de los efectos de la inversión en innovación sobre el progreso técnico del sector industrial de plásticos en Bogotá
Authors: Guarín Salinas Andrés Giovanni , García-Estévez Javier Hernando
Published: August 2021

Esta investigación analiza los efectos de la inversión en innovación y en la contratación de personal cualificado para la gestión de procesos industriales sobre el progreso técnico de las empresas del sector industrial de plásticos en Bogotá. Esta industria se caracteriza por tener un bajo nivel de convergencia estratégica con el territorio y una propensión alta a la imitación de procesos. El enfoque teórico empleado es el de crecimiento endógeno y el de cultura organizacional integracionista. La metodología se desarrolló en dos etapas: en primer lugar, la relación entre innovación, capital humano y nivel de producción se basó en un análisis estadístico longitudinal a partir de la Encuesta de Desarrollo e Innovación Tecnológica de la Industria Manufacturera; en segundo lugar, los factores de involucramiento y adaptabilidad del Modelo Denison se midieron a través de la aplicación directa de una encuesta a las empresas del sector. La investigación encontró que el impacto de las habilidades del personal sobre la producción es significativo y se incrementa con el personal de educación superior. Asimismo, los factores de involucramiento y adaptabilidad se ubicaron en áreas intermedias en las que el uso eficiente de los recursos de producción es moderado.
Cómo medir la apropiación social de la ciencia y la tecnología: La definición de indicadores como problema
Authors: Escobar Ortiz Jorge Manuel
Published: August 2021

Este artículo examina las alternativas que se han ofrecido para definir indicadores de apropiación social de la ciencia y la tecnología (ascyt) en la política científica colombiana. Se muestra que han sido dos perspectivas: la primera postula una equivalencia entre ascyt y percepción pública de la ciencia y la tecnología (ppcyt), y propone que los indicadores de ppcyt se tomen como indicadores de ascyt; la segunda enumera algunas acciones gubernamentales en favor de la ciencia y la tecnología, y propone que la inversión en ciencia y tecnología (incyt) se tome como indicador de ascyt. Este trabajo muestra que ambas perspectivas resultan insatisfactorias. Primero, no se explica qué justifica la equivalencia entre ascyt y ppcyt, lo que permite concluir que tal equivalencia se ha postulado de manera arbitraria. Segundo, no se explica por qué la incyt puede tomarse en sí misma como un indicador de los cambios sobre democratización, cultura científica y generación de pensamiento crítico que se prometen desde el discurso ascyt. Se sigue una metodología de corte cualitativo: una investigación bibliográfica sobre documentos de política científica colombiana, como leyes, decretos, políticas nacionales y encuestas de percepción pública, y un análisis crítico del discurso ascyt de tales documentos.
Alpha variant (B.1.1.7) of SARS-CoV-2 increases fatality-rate for patients under age of 70 years and hospitalization risk overall
Authors: Cetin Meryem , Balci Pervin Ozlem , Sivgin Hakan , Cetin Sirin , Ulgen Ayse , Dörtok Demir Hatice , Li Wentian
Published: August 2021

The emergence of new SARS-CoV-2 variants is a challenge to the control of this pandemic. It is therefore important to collect and to analyze data related to the infection caused by different variants. We have obtained more than 3,700 COVID-19 patients between April 2020 and March 2021 from Tokat, Turkey (roughly 3,100 outpatients and close to 600 inpatients) where about 30% were infected with Alpha variant (B.1.1.7). Descriptive statistics was used to characterize different subgroups. Both logistic regression and cause-specific Cox survival analysis of competing-risk was run on inpatients, to examine the impact of Alpha variant on hospitalization, on mortality and on other factors. We observed that the Alpha variant is over-represented in inpatients than outpatients so infection by Alpha variant increases the chance for hospitalization. The impact of Alpha variant on mortality seems to depend on the patient's age. For patients under age of 70, the case-fatality-rate was 0.84% (5.3%) for patients without (with) Alpha variant (Fisher's test P-value = 2.4 × 10−10). For patients above age of 70, the trend is opposite: the case-fatality-rate is 31.5% (13.6%) for patients without (with) Alpha variant (Fisher's test P-value = 0.0016). The two opposite trends would cancel each other, making other analyses such as cause-specific Cox regression and logistic regression non-significant. The Alpha variant increases the risk for hospitalization, increases the case-fatality-rate for lower age group, and decreases the case-fatality-rate for the upper age group. If the increase of case-fatality-rate in not the most senior group holds true, it should provide useful information for a vaccination planning to counter the impact of Alpha variants.
ANTI-DIABETIC EFFECTS OF GLUCOMANNO-OLIGOSACCHARIDES VIA AMPK ACTIVATION IN C2C12 MYOTUBES
Authors: Do Thien Truong , Tran Nu Thi , Do Que Nguyet Thi , Tran Nhi Thi Y
Published: August 2021

Abstract-HCTN7. In this paper, antidiabetic activities of glucomanno-oligosaccharides (GMO) in vitro and in vivo were investigated. GMO significantly increased AMP-activated protein kinase (AMPK) phosphorylation in a concentration-independent manner. Treatment with 100μg/ml and 50μg/ml of GMO for 1 hour caused 1.47-fold and 1.81-fold phosphorylation of AMPK, respectively. Oral administration of GMO (6g/kg-1 of body weight day-1) lowered blood glucose levels (p < 0.05) at 120 min as compared to control group. These results suggested that GMO exhibited anti-diabetic effects via activation of AMPK and could be useful for diabetes prevention
SYNTHESIS OF NEW QUINAZOLINONE-BASED CONJUGATES AND IN VITRO CYTOTOXIC EVALUATION
Authors: Vu Tran khac
Published: August 2021

A series of new quinazolione derivatives containing a conjugate sytem 13 a-l were synthesized via a three step-procedure. The first step is the condensation of 5-hydroxyanthranilic acid (10) at 160oC for 2 h to afford the intermediate 11 in high yield. This intermediate was then reacted with n-butylamin in acetic acid at 160oC for 14 h to give 12 in 92%. Finally, the reaction of 12 with different aldehydes in acetic acid at 140oC for 14h furnished new conjugates 13a-l in 62-81%. The bioassay results showed that several compounds displayed cytotoxic effect against two cell lines including HepG-2 and SKLu-1 in which 13h exhibited the strongest cytotoxic effect against SKLu-1 with IC50 value of 5.05 µg/mL.
SCREENING FOR VIETNAMESE PLANT EXTRACTS WITH POTENTIAL BENEFIT FOR ANTI OSTEOCLASTOGENESISH
Authors: Nguyen Hai Dang , Le Thanh Huong , Duong Thu Trang
Published: August 2021

Bone's homeostasis is only achieved when there is a balance between bone formation and bone resorption. A metabolic disorder of bone-resorbing osteoclasts can lead to osteoporosis. Long-term use of anti-osteoporosis drugs can lead to undesirable side effects so traditional herbal can be a potential source of alternative medicine. In the present study, forty one Vietnamese plants (seventy methanol extracts) were screened for osteoclastogenesis inhibitory activities on RAW264.7 mouse macrophage cells. For the first time, 29 extracts from 24 species showed potential as effective inhibitors of osteoclastogenesis.
Prejuízos nas habilidades sociais: relações com habilidades de enfrentamento e suporte social
Authors: Aguiar Karoline Giele Martins de , Mello Luana Thereza Nesi de , Andretta Ilana
Published: August 2021

Os usuários de crack necessitam de intervenções que contemplem suas especificidades. Trata-se de um estudo correlacional que objetiva avaliar as habilidades sociais (HS), a relação com as habilidades de enfrentamento (HE), e a percepção do suporte social (PSS) de usuários de crack. Participaram 61 usuários de crack em tratamento no CAPS AD III. Os instrumentos utilizados foram: Inventário de Habilidades Social, Inventário de Enfrentamento Antecipatório para Abstinência de Álcool e outras Drogas, e a Escala de Percepção do Suporte Social. Os resultados indicaram associações entre as HS de autocontrole da agressividade com as HE da assertividade e planejamento, autocontrole emocional e afetividade. Além disso as HS em sua totalidade foram correlacionadas com o afeto e com o total das dimensões de PSS. Dessa forma, prejuízos relacionados ao autocontrole em usuários de crack tem associações com as HE e com a PSS.
Esquemas iniciais desadaptativos em adultos brasileiros: revisão narrativa da literatura
Authors: Fiuza William Macedo , De Godoy Rossane Frizzo
Published: August 2021

O objetivo deste artigo foi identificar estudos produzidos no Brasil que tenham investigado esquemas iniciais desadaptativos em adultos. O delineamento foi qualitativo-exploratório, por meio de uma revisão narrativa da literatura, tendo como fontes estudos empíricos produzidos no Brasil publicados no período de 2010 à 2018, nas seguintes bases de dados: PsycINFO, BVS-PSI e o portal de periódicos da CAPES. Foram selecionados 16 artigos que investigaram a relação dos EID’s com os seguintes grupos: homens e mulheres, pais, mães e habilidades sociais educativas, universitários e empatia, sintomas depressivos, ansiosos e dismorfismo corporal em universitários, bullying em universitários, pacientes com enxaqueca, uso de álcool e outras drogas, transtorno da acumulação, violência conjugal, ajustamento diádico na conjugalidade, pacientes bariátricos, pessoas com sintomas de disfunção temporomandibular, pacientes internados por tentativa de suicídio e indivíduos que praticaram crimes. Uma das temáticas mais recorrentes foi a violência conjugal. Nos três estudos que abordaram o assunto, foi identificada uma possível associação com o 1º domínio esquemático (desconexão e rejeição). Foi observado o aumento gradativo de estudos brasileiros com a identificação de EID’s e o uso das versões reduzidas do inventário de esquemas de Young. Como limitação deste artigo, percebe-se a variedade de métodos nos estudos registrados, o que dificultou uma análise mais detalhada de tais produções. Ampliar esse campo de pesquisa pode favorecer entendimentos de diferentes contextos sob o viés da terapia do esquema, possibilitando intervenções terapêuticas e de prevenção mais efetivas.
MARG szenzor alapú pozíció becslés periodikus mozgásra
Authors: Nagy Balázs
Published: August 2021

The research examined the fusion of signals from magnetometer, gyroscope and acceleration sensors (MARG sensor). The focus of the article is the sensor fusion by supervised learning, which is an estimate of the situation based on the parallel processing of different types of measured data in the case of periodic movements. The applicability of the learning algorithms was examined through a practical example of a pendulum.
On the Impact of Digital Technologies on Modern Society
Authors: Kolesov Mikhail V.
Published: August 2021

The article analyzes the changes that have occurred in public life and legal relations during the period of rapid development and implementation of information and communication technologies. Based on the presented facts and observations, the necessity of normative regulation of various processes and persons in the digital space is substantiated. Government agencies must seriously adapt to modern challenges.
Object of the Crime as a Symbol in the Doctrine of the Composition of the Crime
Authors: Goncharova Natalya S.
Published: August 2021

The author attempts to determine the place of the object of the crime in the doctrine of the composition of the crime. They analyze the views of scientists available in legal literature at various historical stages in the development of Russian legislation pertaining to criminal acts. Pre-revolutionary criminal legislation did not distinguish between the objects and the subjects of the crime. At the beginning of the 20th century, Russian criminal law science began to realize the need to distinguish the objects of crimes from the subjects. Since 1953, in connection with liberalization, there has been a clear definition of the subject of crimes, depending on their composition. Further development of the doctrine of the subject of crimes is characterized by a wide variety of scientists views, which the author analyzes, combining them into two groups, depending on the location of the subject of the crime as part of the crime: 1) the subject of the crime is a sign of the objective side of the crime and does not depend in any way; 2) the subject of the crime is a sign of the object of the crime and is inextricably linked with it.
PENGARUH KEMAMPUAN BERPIKIR KREATIF PESERTA DIDIK MELALUI PEMBELAJARAN MODEL LEARNING CYCLE ENGAGEMENT EXPLORATION EXPLANATION ELABORATION DAN EVALUATION DISERTAI MIND MAPPING
Authors: Meidiyanti Syamilah , Damayanti Eka , Syamsudduha St , Jamilah Jamilah
Published: August 2021

Abstrak. Penelitian ini bertujuan untuk mengetahui (1) perbedaan kemampuan berpikir kreatif sebelum dengan setelah penggunaan model pembelajaran learning cycle engagement, exploration, evaluation, elaboration, dan evaluation (5E) disertai mind mapping pada peserta didik di SMAN 8 Bulukumba; (2) apakah ada pengaruh penerapan model pembelajaran learning cycle engagement, exploration, evaluation, elaboration, dan evaluation (5E) disertai mind mapping terhadap kemampuan berpikir kreatif pada peserta didik di SMAN 8 Bulukumba. Jenis penelitian penelitian quasi eksperimen, dengan pretest posttes group design. Instrumen yang digunakan berupa tes kemampuan berpikir kreatif dan lembar observasi pelaksanaan pembelajaran. Data diolah menggunakan analisis statistik deskriptif dan inferensial paired sample t-test. Hasil analisis deskriptif menunjukkan rata-rata skor kemampuan berpikir kreatif sesudah perlakuan lebih tinggi dibanding rata-rata skor kemampuan berpikir kreatif sebelum perlakuan. Hasil analisis inferensial menunjukkan p sebesar 0,000, hal ini berarti terdapat perbedaan skor kemampuan berpikir kreatif sebelum dan setelah diberikan perlakuan. Maka dapat disimpulkan bahwa kemampuan berpikir kreatif peserta didik dapat ditingkatkan melalui pembelajaran model learning cycle 5E disertai mind mapping.Abstract. This research aims to understand: (1) The differences in creative thinking abilities of the students of SMAN 8 Bulukumba before and after using learning model of cycle engagement, exploration, evaluation, elaboration, and evaluation (5E) with mind mapping, (2) The effect of learning model of cycle engagement, exploration, evaluation, elaboration, and evaluation (5E) with mind mapping implementation towards students’ creative thinking abilities. This quasi experiment research done with pretest posttest group design. The Instruments used were creative thinking tests and learning implementation form. Data was analyzed descriptively and inferentially to paired sample t-test. Based on descriptive analysis, it showed the average score of creative thinking abilities of students after using the learning model was higher than the score before using the learning model. The inferential analysis showed the P value was 0,000 means there is a difference in score of creative thinking abilities before and after the implementation of the learning model. It can be concluded that the learning model of 5E with mind mapping might improve students’ creative thinking abilities.