bluuebunny/crossref_metadata_2025 huggingface dataset:
Recaída de linfoma de Burkitt en paladar
Authors: Medina Jessica , Boccalatte Luis A.
Published: October 2022

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¿Las vacunas anti-COVID-19 disponibles se diferencian en eficacia en personas mayores?
Authors: Rozenek Miriam
Published: October 2022

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Peirce con Bajtin. Una lectura icónica de los cronotopos cinematográficos
Authors: Abril Gonzalo
Published: October 2022

En la teoría de la novela de M. Bajtin los cronotopos articulan estéticamente el tiempo, el espacio y la “imagen humana”. Esta concepción se puede extrapolar a las narraciones audiovisuales y al análisis fílmico. Y puede también complementarse con la aplicación de los conceptos de imagen, diagrama y metáfora propuestos por Ch. S. Peirce. Una lectura del conocido film Rashomon, de A. Kurosawa, se propone como ejemplo experimental y didáctico de este intento teórico-metodológico. Que concierne, más en general, al estudio de la mediación simbólica en la producción artística moderna.
Presentación del número: Semiótica de la cultura. Perspectivas para el análisis mediático
Authors: González Rayco , Serra Marcello
Published: October 2022

Presentación del número
Antimicrobial susceptibility of mastitis pathogens of dairy cows in Ukraine
Authors: Zhuk Yurii , Zaritskyi Ruslan , Dreval Denys , Derkach Serhii , Kovpak Vitalii , Masalovych Yurii , Ochkolyas Olena , Bazyvoliak Svitlana , Antypov Yevheni , Kharsika Iryna
Published: October 2022

Mastitis is one of the most common diseases on dairy farms. It causes significant economic damage associated with the cost of treating sick cows, reduced milk yield and quality indicators of dairy products, and the risk of premature culling of animals. Treatment of cows with mastitis on dairy farms is carried out mainly with antimicrobial drugs, which are usually used without a preliminary test to identify the causative agent of the disease and determine its sensitivity to antimicrobial substances, which is an important part of the effectiveness of therapy. Increasing the resistance of bacteria to antimicrobial substances poses a threat not only to the animal but also to humans, as a consumer of dairy products. The availability of data on the sensitivity of mastitis pathogens to antimicrobial drugs makes it possible for veterinary doctors to choose the most effective antibiotic for treating animals with the shortest duration of treatment. The presented results of studies of breast secret samples taken from cows indicate that in 57.5% of cases, contagious pathogens of mastitis were identified. In particular, Streptococcus agalactiae made 24.1%, Staphylococcus aureus – 18.4%, Corynebacterium spp. – 7.2%, Streptococcus dysgalactiae– 5.6%, Streptococcus uberis – 2.2%. Environmental pathogens accounted for 42.5% of the total number of isolated isolates, among which Streptococci represented gram-positive microflora at 11.5 Streptococcuscus spp. (6.2% Streptococcuscus parauberis (4.4% Streptococcuscus Bovis (0.9%) and Staphylococcus spp. – 10.3%. Gram-negative microflora is 20.6%, among which the largest percentage belongs to E. coli – 8.4% and Klebsiella pneumonia – 1.9%. Mastitis caused by yeast accounted for 1.4% of all diagnosed pathogens. Antimicrobial sensitivity was evaluated using the disk diffusion method (Kirby-Bauer). According to the results of determining the sensitivity of mastitis pathogens to antimicrobial substances, it was found that the highest sensitivity of the isolated isolates was to Ceftiofur, Amoxicillin/clavulanic acid, Rifampicin, Amoxicillin, Gentamicin, Ampicillin, Bacitracin, Cephalexin, Cloxacillin, Enrofloxacin, Trimethoprim/sulfamethoxazole, Oxytetracycline, Lincomycin. The least sensitive – to Spiramycin, Tylosin, streptomycin, neomycin, Marbofloxacin, Tilmicosin, and Danofloxacin.
THE EFFECT OF SUBCLINICAL KETOSIS ON THE HEMATOLOGICAL INDICATORS OF THE BLOOD OF HIGHLY PRODUCTIVE COWS
Authors: Nikitin G. , Shiryaev G. , Nikitkina E.
Published: October 2022

Purpose: to study the effects of subclinical ketosis on the hematological indicators of the blood of highly productive milk cows in the postal period. The studied animals are selected according to the principle of conditional analogues and divided into 3 groups of 5 goals each. Depending on the concentration in the blood of 3-hydroxybutirate, animals were divided into 3 groups: 1st group-less than 0.8 mmol/l; Group 2-1.2-1.4 mmol/l; 3rd group-more than 1.4 mmol/l. The conditions of their detention and feeding were the same for all groups. The determination of the level of 3-hydroxybutirates took place 2 times: on the 5th and 15th day after the hotel. Taking blood was carried out from the tail vein in front of the morning feeding. The blood serum was obtained by centrifugation (3000 rpm) with subsequent freezing at -20 ° C. The following indicators were determined in the samples: red blood cells, hemoglobin, hematocrit, the total volume of red blood cells, the average hemoglobin content in red blood cells, the distribution of red blood cells in the blood, leukocytes, granulocytes, monocytes, lymphocytes, thrombocytes, the average volume of platelets. Reliable differences have been established in the case of indicators of the level of red blood cells, hemoglobin and hematocrit in comparison of the 1st and 2nd groups with the 3rd group. A reliable correlation between the level of 3-hydroxybutirates and some hematological indicators (on various days after the hotel) has been established.
CHANGES IN HEMATOLOGICAL BLOOD PARAMETERS IN HORSES PARTICIPATING IN EQUESTRIAN DISTANCE RUNS
Authors: Semenov B. S. , Guseva V. A. , Kuznetsova T. Sh. , Nazarova A. V.
Published: October 2022

The article provides information on the impact of training on clinical blood parameters in horses participating in equestrian distance running competitions, the distance length is 40 km. The animals were divided into two groups, 10 heads each. The first group included horses that were trained one week before the races, the second included animals that were trained two weeks before the competition. As a result of the research, it was revealed that in the case of training within one week before the competition, horses had a statistically significant increase in the number of segmented neutrophils compared to the indicators before the start. This is probably due to the fact that with heavy physical exertion, muscle tissue begins to be injured in insufficiently trained animals, as a result of which the body needs to dispose of the products of muscle tissue metabolism. During the training for two weeks before the competition at a distance of 40 km, the level of segmented neutrophils in the blood of horses did not differ from the data before the start. An increase in red blood indicators was determined in all experimental horses after the runs, when compared with the data before the load, but these indicators did not go beyond the reference values. This is probably due to dehydration, which often develops when walking a long distance. There was also a statistically significant decrease in the level of lymphocytes after exercise in both groups of horses when compared with the indicators before the start. At the same time, these indicators did not go beyond the reference interval.
REGENERATIVE PROCESSES IN THE RENAL BODIES AFTER PRIVATE NEPHRECTOMY WITH THE USE OF THE ALLOPLANT SUTURE FOR SEWING
Authors: Sidelnikov A. I. , Kvochko A. N. , Nekrasova I. I.
Published: October 2022

To date, the study of the process of cell proliferation in organs and tissues, as well as the possibility of its stimulation is very important in many types of pathology. Primary damage to somatic cell types in the glomerular apparatus of the kidneys is associated with various pathologies. Damaged endothelial and mesangial cells are restored due to the proliferation of neighboring cells. To study the reparative processes in the renal corpuscles, the change in the number of Ki-67+ cells was assessed. Ki-67 is expressed in the cell nucleus at all stages of the cell cycle, except for G0. Therefore, the number of Ki-67+ cells reflect proliferative activity. The search for new ways to stimulate organ regeneration and methods for its evaluation is an important direction. When evaluating the Ki -67 protein in the cells of the renal corpuscles, three types of expression are distinguished: granular, diffuse, and granular-diffuse. We found that an increased (by 40.21%) number of Ki-67+ cells in the damaged area on the 3rd day indicates active regeneration processes, then from the 6th day the values of this parameter decrease, but still remain higher. than during surgery. We associate such dynamics of changes in the studied parameter with alteration and active inflammatory processes localized in this zone. In the zone without damage, we noted a wave-like dynamics of changes in the number of Ki-67+ cells in the renal corpuscles in the zone without damage with 2 periods of increase (on the 3rd and 18th days) and a decrease to the values obtained during the operation by 60 -m days. We believe that this indicates an early (3rd day) regenerative activity of cells, as well as the process of tissue remodeling. Our results can help improve the diagnosis and treatment of animals with kidney pathologies.
METHOD FOR PREVENTION OF DISEASES IN THE AREA OF FINGERS IN SHEEP
Authors: Finageev E. Yu. , Ladanova M. A.
Published: October 2022

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COMPARE THE DEGREE OF INFORMATION OF MODERN METHODS OF DIAGNOSTICS OF SPORT HORSES
Authors: Titova E. V. , Zakharov A. Yu.
Published: October 2022

In connection with the development of equestrian sports, the proportion of traumatic injuries of the musculoskeletal system of sports horses is also increasing. In the working activity of a modern veterinary specialist, visual research methods should have certain qualities, namely: they should be small in size for ease of transportation to various points in the city or region, easy to apply in practice, and also qualitatively visualize the location of the pathological focus. That is why the search for the most effective method of visual diagnosis of diseases accompanied by injuries of the musculoskeletal system is an important direction in scientific research. To conduct this study, 10 dressage horses with traumatic injuries of the superficial flexor of the thoracic limbs were examined in the conditions of equestrian complexes in the Leningrad Region. Conducted a study on the information content of various diagnostic methods, in particular thermographic, ultrasound and radiological. Comparing the degree of information content of modern methods, we can conclude that for an accurate diagnosis and a complete analysis of traumatic injuries, it is necessary to use various methods of visual diagnostics. Improvement of known methods, in particular, such as infrared thermography, will make it possible to identify injuries of the musculoskeletal system of horses at the early stages of the development of the disease, immediately before the onset of clinical signs, and to monitor changes in dynamics for the selected treatment regimen. Accordingly, timely diagnosis and prognosis of injuries remains an open topic for research in the scientific activities of veterinarians, therefore, we consider the search for new methods that meet the criteria used to identify several groups of diseases at once is relevant and significant.
Libro guía del facilitador para formar cuidadores familiares
Authors: Peñarrieta de Córdova María Isabel , Gutiérrez Gómez Tranquilina , León Hernández Rodrigo César , Piñones Martínez María de Socorro , Quintero Valle Luz María , Flores Barrios Florabel , Flores Barrios Carina , de la Cruz Palomo Azela Angélica , Díaz Rentería María Guadalupe , Cruz Quevedo Juana Edith , Velásquez Domínguez Francisca , Solís Solís Virginia , Velásquez Salinas María Elena , Lema Morales Julia María Eugenia , Montalvo Luna Mery Soledad
Published: October 2022

Por primera vez en el contexto latinoamericano, esta obra presenta el resultado de años de trabajo de investigación con participación de personas en condiciones crónicas o con algún nivel de dependencia, así como del cuidador familiar que está a su cargo la mayor parte del tiempo, el cual se realizó en tres países de Latinoamérica: México, Perú y Colombia. Los resultados de estas investigaciones han permitido aprender e identificar necesidades de los cuidadores familiares y de las personas con cronicidad, las cuales pueden ser abordadas de manera adecuada a través de programas educativos. Es así como se elaboró, implementó y evalúo el programa “Trabajando juntos en colaboración” para ser aplicado por profesionales de la salud. A través de esta obra se propone de manera muy práctica y clara un abordaje diferente de educación en salud que permite cambios de comportamiento que promueven el automanejo-autocuidado y el cuidado en casa por parte del cuidador familiar, aspectos que no han sido publicados aún en contextos latinoamericanos. Se describe el comportamiento del automanejo en un cuidador y los contenidos a considerar en un programa que promueva este comportamiento.
IMPLEMENTATION OF EXERCISE SUPERVISION IN INDONESIA
Authors: Afifah Ifatul
Published: October 2022

The government through the Directtorate General of Imigration, Ministry of Law and Human Rights of the Republic of Indonesia, has carried out one of its duties and functions, namely the supervision of foreigner residing in the teritory of Republic Indonesia. In accordance with Law Number 6 of 2011 concerning Immigration. The implementation of such supervision is carried out with the aim of law enforcement, especially on immigration law. The Immigration Office, which is the technical implementation unit of immigration in the regions, has carried out the duties and functions of supervising foreigners who are in its working area since the enactment of Law Number 6 of 2011 concerning Imigration until now. The results of the study found that the implementation of supervision of foreigners at the Immigration Office in Indonesia had been carried out properly based on Law No. 6 of 2011 concerning Imigration and Regulations of the Ministers of Law and Humans Right No. 4 of 2017 concerning Procedures for Immigration Supervision. faced in the form of shortages in the number of supervisory personnel, the wide range of work areas and a limited budget.
STRENGTHENING IMMIGRATION FUNCTION AS FACILITATOR OF COMMUNITY WELFARE DEVELOPMENT IN MOROTAI SPECIAL ECONOMIC ZONE
Authors: Akbar Filianto
Published: October 2022

Morotai Island Regency has a geoeconomic and geostrategic strategic location and is an area with great potential both in terms of tourism, the fishing industry, and various other industries. This potential has made the government set Morotai as a Special Economic Zone (SEZ) since 2014. This paper aims to find out the extent of the development of the Morotai SEZ on the regional economy and increase the welfare of the community, as well as know the role of immigration that can be carried out as a manifestation of one of the immigration functions, namelydevelopment public welfare. The results show that after the Morotai SEZ, although there has been an increase in local revenue, it has not significantly and consistently affected the economy due to the suboptimal use of local government over the potential of the Morotai SEZ. The role of the immigration function in the Morotai SEZ region must also be strengthened through the establishment of an immigration work unit in the Morotai SEZ region and  the improvement of other immigration cooperation in order to facilitate the opening of international access, community mobility and business actors in various industries in Morotai, including other regions in eastern Indonesia, with the aim to improvethe welfare of the community.
IMMIGRATION SUPERVISION ON SEA TRANSPORTATION IN THE IMMIGRATION EXAMINATION PLACE OF TANJUNG PERAK SEA PORT
Authors: Simbolon Mangapul Alexus
Published: October 2022

For the sake of realizing the upholding of state sovereignty and security, Indonesia must prioritize the duties and functions of Immigration in filtering people who want to enter or leave the territory of Indonesia by upholding the principle of Immigration, namely selective policy, especially for immigration officers at immigration checkpoints at airports, ports, and even at cross-border posts that must always prioritize this principle, that is, only foreigners who benefit and benefit the Indonesian state can enter Indonesian territory. Increased supervision of sea transportation means at the Tanjung Perak Seaport TPI must start from reforming the rules in carrying out immigration duties and functions by prioritizing immigration landing SOPs, regulation and availability of adequate budget preparation human resources as well as an increase in the welfare of officers in carrying out their duties both regarding the availability of equipment. transportation and accommodation outside the area. Permenkumham Number 44 of 2015 has not been implemented optimally, the old habits that have traditionally been in the landing task are still running. This mindset is clearly no longer appropriate to the current situation with rapid technological advances and is not in line with the Kemenkumhan Values, namely "PASTI".
THE INVOLVEMENT OF INDONESIAN ARMED FORCE IN OVERCOMING TERORRISM AS A TRANSNATIONAL ORGANIZED CRIME
Authors: Herdayatamma K L
Published: October 2022

Globalisasi dan kemajuan teknologi membuat negara-negara di dunia sekaan tidak memiliki batas nyata (borderless world). Kondisi ini memudahkan bagi aktor internasonal memberikan pengaruh terhadap suatu negara dengan atau tanpa keberadaan dari aktor tersebut. Kemajuan teknologi tidak hanya berdampak positif, tetapi juga berdampak negatif (dual use). Kemunculan kejahatan terorganisir transnasional merupakan salah satu dampak negatif dari kemajuan teknologi. Kejahatan ini merupakan ancaman serius bagi negara-negara di dunia, khususnya negara berkembang dan rawan konflik. Terorisme merupakan salah satu bentuk kejahatan terorganisir transnasional yang dapat mengancam kedaulatan negara, keutuhan wilayah, dan keselamatan bangsa. Penelitian kepustakaan digunakan sebagai metode pada penelitian ini. Data dikumpulkan dari sumber-sumber sekunder yang relevan dengan topik, selanjutnya dilakukan analiss, pengorganisasian, dan penyajian data. Dari penelitian yang dilakukan, diketahui bahwa pelibatan Tentara Nasional Indonesia merupakan langkah yang tepat dalam pengatasi terorisme sebagai kejahatan terorganisir transnasional, mengingat tugas pokok dan fungsi, serta kapasitas dan kapabilitas Tentara Nasional Indonesia.
THE INDONESIAN E-GOVERNMENT INITIATIVES: DEVELOPMENT STAGES OF E-GOVERNMENT IN IMMIGRATION LAW ENFORCEMENT
Authors: Maulana Ramacesa Nije
Published: October 2022

E-government in Indonesia is still developing particularly in some regional and central government offices. As a central government, the directorate general of immigration has been implemented very well in relation to the process of providing immigration documents such as passports, visas, and permission to stay for foreigners.  However, in the field of law enforcement the directorate general of immigration have failed to demonstrate the development phase of e-government. The official website of the directorate general of immigration does not provide any information related to immigration law enforcement so that the legal awareness of the public about the dangers of violating immigration law is not well conveyed. Even the public does not know the investigation process if they commit immigration violations. Also, the agency did not provide both financial and nonfinancial access for the public to avoid immigration violations. All coordination activities are still done manually. The data used in this study is secondary data collected from academic literature and grey literature. The research materials were obtained by using search engines from google, google scholar, and an online library at flinders university.
ETHNIC TENSIONS IN CHINA: XINJIANG CONFLICT IN CONSTRUCTIVISM PERSPECTIVE
Authors: Sinaga Melpayanty , Y Yusril
Published: October 2022

The People's Republic of China is one of the multi-ethnic countries in this world that is facing a number of prominent ethnic issues, including the Xinjiang Conflict which has received international attention in recent years. In the China's western autonomous region, ethnic tensions exist between the Han majority and the Uighur minority. This research is using a qualitative-descriptive method by relying on library studies from available secondary sources, this paper will try to explain the tension between the Uighurs and Hans ethnic groups through a constructivism perspective. In constructivism perspective, identity is one of the main ideas that shape the pattern of interaction between actors. It was found that the construction of Uighur and Han ethnic identities contributed to the creation of this ethnic tension, which is also related to how the conception of China's national identity is constructed.
SHIFTING BUSINESS ENVIRONMENT AND BORDER AREAS
Authors: Prasetya Agustian Budi
Published: October 2022

Abstract: Business environment transformation drives by the growth of internet-based technology and movement of goods and people migration across borders. The digital technology connects all nations, business actors and netizen within network ecosystem that make migrants across border engaged to the jurisdiction and nation sovereignty as well as engage to the similar civil rights, worker right and human rights and the global netizen.  This article examines  business competitiveness in Indonesia through borders management area. Method is desk research, utilizing academic references data. The discussion and analysis cover the ideas of managing synergetic multistakeholders in border area, positioning migrants as research, primary stakeholder that entitled for border area services and sources for investment opportunities, and conduct governance based on universal human rights, Indonesian national interest, as well as providing business certainty and security protection for migrants and foreigners
PERAN INTELEJEN KEIMIGRASIAN DALAM UPAYA PENCEGAHAN KEJAHATAN TANSNASIONAL DI INDONESIA
Authors: Antomarta Adhitya , Mansur Wilda Ramadhani
Published: October 2022

Crime is increasing in this day and age. Not only a crime in the real world but also in cyberspace such as hacking, cyber crime, and others. Which in the end has the potential to give birth to a sense of discomfort in social life. Indonesia as a sovereign country, the drafting of government regulations is based on the 1945 Constitution of the Republic of Indonesia. As a sovereign country, the Republic of Indonesia in its legal development cannot be separated from the laws governing foreigners, besides that it also regulates Indonesian citizens. The immigration control function plays an important role in maintaining the security and security of the country from all forms of internal and external disturbances. In this study, we will discuss the role of Immigration Intelligence in monitoring foreigners and the obstacles and steps that must be faced by the Directorate General of Immigration in carrying out the function of Immigration Intelligence. In this study, the author uses a qualitative approach by collecting and utilizing information and data related to the problems discussed. The role of intelligence in the supervision of foreigners is certainly in line with the immigration function, namely supervision where this is due. In connection with this supervision, some of the obstacles experienced become obstacles, namely the UPT which is still not developed evenly in every cross-border city in Indonesia, the quality of the employees who are also still not good at carrying out the assigned tasks, regulations that are still incomplete in carrying out the tasks assigned to them. manage foreigners. With some of these obstacles, it is not an excuse for the Directorate General of Immigration to supervise foreigners, the Directorate General of Immigration also takes steps in an effort to supervise foreigners by issuing policies called selective policies. With these policies, it is hoped that the supervision of foreigners in immigration intelligence can run well and all existing obstacles will be overcome. Suggestions that can be conveyed by the author is the supervision of the implementation of the policies issued and the improvement of human resources.
ANALYSIS OF THE APPLICATION OF LABELLING THEORY IN INDONESIAN IMMIGRATION GLASSES: A CASE STUDY OF NIGERIAN DIPLOMATS WHO ARE SUSPECTED TO BE VICTIMS OF "MURSERY" BY THE IMMIGRATION OFFICERS IN SOUTH JAKARTA
Authors: Dhiba Hana Farah , Pratama Fachrizza Sidi , Ismarus Rafsanjani
Published: October 2022

The misunderstanding of the video footage of Immigration officers checking Nigerian foreigners which went viral on social media which then created various speculations and misunderstandings in the community. However, the circulating footage only shows when the officers fought and defended themselves against the foreigner and the foreigner shouted "I can't breathe, I can't breathe" thus making the atmosphere cloudy. The case of alleged mistreatment of Nigerian diplomats by unscrupulous immigration officers has attracted public attention and has become a trending topic in various media. This indirectly causes various versions of the series of events that appear on social media. Our society and Indonesian immigration officers are applying the theory of labeling sequentially, the process starts with the primary deviance, namely by naming Nigerian citizens as rioters or perpetrators of violations and secondary deviance applies because since the label was given to Nigerian citizens, the level of crimes committed has increased and always there every year. the second reaction is that the community is against it, this happens because they have a negative stigma and give a bad label to black citizens including Nigerian citizens. Therefore, they confirmed that in handling and securing the Nigerian citizens, immigration officers had to use violence for fear of unwanted things such as the WN running away, rebelling and the like.
SUCCESS ANALYSIS OF THE CHAMPION DOOR APPLICATION USING DELONE & MCLEAN SUCCESS MODEL
Authors: Prabadhi Isidorus Anung , Wilonotomo W , Ramadhana Abduhafizh
Published: October 2022

The high intensity of immigration data requests is the reason behind the issuance of the Pintu Sijuara application. In line with the implementation of an information system, it is necessary to conduct a post-implementation review. Therefore, this study aims to analyze the success of the application using the Delone & Mclean success model. The sampling technique uses saturated sampling by taking the entire population as the research sample. In the data analysis process, respondents use SPSS as a tool for descriptive statistical analysis and use the PLS-SEM approach with the help of the SmartPLS tool for inferential statistical analysis. By the nine hypotheses, there are three accepted hypotheses: the relationship between service quality and interest in the use, the relationship between interest in the use and net benefits, and user satisfaction with net benefits. The three hypotheses gave positive and significant results as evidenced by the path coefficients and T-Statistics values. Based on the result, "Pintu Si Juara" in Immigration Office Class 1 Special Border Control Surabaya can be said to have good results. However, it can still be developed and improved to be even better by improving in dimensions of service quality that have a significant positive relationship to interest in the use and net benefits
ANALYSIS OF E-ARRIVAL CARD SYSTEM WITH COBIT 5 FRAMEWORK IN THE DELIVER, SERVICE, SUPPORT (DSS) DOMAIN
Authors: Wilonotomo W , Putra Wahyu Eka , Muhaemin Dedi
Published: October 2022

E-arrival card is an electronic arrival card that is used to collect data on foreigners entering Indonesia. Bandung Immigration Office Class I of Border Control is one of the Immigration Offices in West Java that has implemented an electronic arrival card called IDN E-Arrival Card Jabar. Every foreign citizen who enters Indonesia through the Immigration Checkpoint of Husein Sastranegara International Airport is required to fill in data on the e-arrival card system. This e-arrival card system must run with maximum and optimal conditions, therefore an analysis system is needed to determine the service performance and security of the e-arrival card system by carrying out an audit process. The audit process using the COBIT 5 framework. The purpose of this study is to measure the capability level of the e-arrival card system and provide recommendations and suggestions regarding the results of measuring the capability level of the e-arrival card system using the COBIT 5 framework in the DSS (Deliver, Service, Support) domain. The research method used is qualitative using the COBIT 5 framework. The results obtained regarding the measurement of capability level on the e-arrival card system with the COBIT 5 framework in DSS01 (manage operations) are at level 4 is predictable process, for DSS02 (Manage service requests and incidents), DSS03 (Manage problems), DSS04 (Manage continuity), DSS05 (Manage security services) and DSS06 (Manage business process controls) are each at level 3 is established process. Recommendations that can be given are to carry out periodic maintenance and evaluation as well as to make standard operating procedures (SOP) for services and incidents regarding the e-arrival card system.
MAKING AN APPLICATION FOR DETERMINING THE RANKING OF IMMIGRATION POLYTECHNIC STUDENTS WITH THE WEBSITE-BASED PROMETHEE METHOD
Authors: Hertantyo Galuh Boy , Wilonotomo W , Noviansyah Dhimas Triand
Published: October 2022

In the process, based on the ranking of the Immigration Polytechnic cadets, the number of considerations objectively indicators or criteria that have been determined. These indicators and criteria have weight values that will be analyzed quickly and structured. So we need a system to help the Immigration Polytechnic make a list of these people or multi-criteria. This study uses the Preference Ranking Organization Method for Enrichment Evaluation (PROMETHEE) as a Decision Support System (DCS). The PROMETHEE method is one of the groups in the Multi-Criteria Decision Making (MCDM), which will analyze using many indicators or multi-criteria. It will produce output in the form of decision recommendations to its users. In addition, the PROMETHEE method will compare the value of one alternative with another alternative and produce a ranking based on the value that Immigration Polytechnic students get. Researchers conducted two tests by comparing the results of the test data and the results of the system. The tests are accumulated and calculated using the formula for the estimation of the confusion matrix. The final score is 90% which is included in the Excellent Classification and Best Classification.
EFEKTIVITAS PENGGUNAAN APLIKASI E-SURVEY TERHADAP PELAYANAN KEIMIGRASIAN BAGI WARGA NEGARA INDONESIA DI KANTOR IMIGRASI KELAS I TPI KUPANG
Authors: Prabadhi Isidorus Anung , Akbar Rasona Sunara , Filitzia Waso Justine Mariana
Published: October 2022

Based on Law of Republik of Indonesia Number 25 of 2009 concerning public services, a public service provider must involve the community as a way or effort to build a fair, transparent and accountable system. The e-survey application provides convenience for users of immigration services in terms of accessing and providing an assessment of immigration services. Through this e-survey application, it is expected to improve the quality of immigration service performance to be better than before. This study aims to determine the effectiveness of the e-survey application on immigration services for Indonesian citizens at the Class I Checkpoint Immigration Office of Kupang, and what factors are supporting and inhibiting the effectiveness of using the e-survey application. The type of method used is descriptive qualitative - descriptive, with data collection carried out through interviews, observations, and documentation. Data analysis techniques are carried out by data reduction, data presentation, as well as drawing conclusions and verification. The results of this study indicate that the use of the e-survey application is running effectively, this is measured by using the four effectiveness indicators. The use of the e-survey application is supported by a QR-Code provided in banners and small boards. As well as to facilitate access for the public, free wifi is provided. While the inhibiting factor is unstable network conditions, not all applicants have smartphones and smartphones that don’t support QR-Code reading.
Didática em cursos de formação de professores: concepções e perspectivas
Authors: Rosa Luana Bastos do Nascimento , Aroeira Kalline Pereira
Published: October 2022

Esta produção analisa questões relacionadas com a disciplina Didática no contexto de cursos de licenciatura, colocando em discussão a centralidade que essa área de conhecimento assume no processo de formação dos professores com base na perspectiva crítica, problematizando as concepções de docentes sobre a Didática no ensino superior. Mostra, em perspectiva, respostas às questões: quais papéis a Didática assume no processo de formação de professores conforme os debates contemporâneos dessa área no Brasil? Que concepções docentes que atuam com essa disciplina em cursos de licenciaturas possuem quanto à contribuição da Didática na formação de futuros professores? O que mais está em evidência nesta obra é a concepção de que a Didática se apresenta como disciplina essencial para a constituição do saber do futuro professor e como área da Pedagogia que tem a finalidade de fundamentar os processos de ensino e aprendizagem, voltada para a inclusão social e emancipação humana. A convicção de que o livro poderá contribuir para ampliar a compreensão das discussões com relação à Didática na formação de docentes e suas possibilidades nesse contexto animou-nos a publicá-lo.
História da Diocese de Campos: cem anos de evangelização (1922-2022)
Authors: Ribeiro Márcio André dos Santos , Paz Roberto Ferrería
Published: October 2022

História da Diocese de Campos: Cem Anos de Evangelização (1922-2022) aborda as intenções e a concretização da criação da Diocese com os períodos dos sete Bispos que a governaram neste centenário, destacando a obra de Dom Carlos Alberto Navarro e Bispo Emérito Dom Roberto Guimarães. Além disso, as obras que marcaram cada governo pastoral. Para representar as inúmeras festas e procissões religiosas, foram contempladas a Festa do Santíssimo Salvador e o Caminho de Santo Amaro. Os movimentos, as congregações e as irmandades foram citadas, e a história da criação do Seminário Diocesano e do Carmelo São José foram descritas pelos seus dirigentes. Que as histórias deste livro sirvam de inspiração às comunidades paroquiais na preservação e divulgação dos bens imateriais e materiais, e reforcem o sentimento de pertencimento a essa grande comunidade Diocesana de Campos.
Antioxidant Activity Test of Red Pidada Leaves (Sonneratia caseolaris L.) using ABTS Method (2,2-azinobis-(3-ethylbenzothiazolin)-6-sulfonicacid)
Authors: Siswanto Syamsul Eka , Supomo Supomo , Jubaidah Siti , Wijaya Heri , Lestari Dwi , Poddar Sandeep
Published: October 2022

The Red Pidada (Sonneratia caseolaris L.) is one of the plants used in traditional ways, especially by Borneo's people, where the red Pidada leaves are used as a cool powder composition and applied to the face while doing activities under exposure to sunlight over a long time. Red Pidada extract has a very strong antioxidant activity of 21.62 ppm because it has secondary metabolite, which is a medicinal ingredients and have a strong molecular structure, and have various biological activities. Pidada redplant (Sonneratia caseolaris L.) is a mangrove that has antioxidant potential. Free radicals can cause cancer, heart disease, premature aging, and other degenerative diseases. The research objective was to determine the antioxidant activity of the Pidada red leaf extract and fraction.The research was conducted qualitatively and quantitatively. The qualitative test was carried out by the colour change test and the quantitative test using the ABTS method (2,2-azinobis-3-ethyl benzothiazolin-6-sulfonic acid) with a UV-Visspectrophotometer. Pidada redleaves were extracted and fractionated, namely ethanol extract, n-hexane fraction, ethyl acetate fraction, and ethanol fraction, and made inti various concentrations compared to vitamin C.The IC50 value determined the antioxidant activity. The results showed that the ethanol extract had an IC50 value of 1.32 ppm (very strong), n-hexanefraction of 19.89 ppm (very strong), ethylacetate fraction of 0.50 ppm (very strong), and ethanolfraction of 1.63 ppm (very strong).
Synthesis and Antimicrobial and Anticancer Activity of β-Carboline Analogues
Authors: Awasthy Avneesh , Prakash Agrawal Om
Published: October 2022

The β-carboline alkaloids possess a wide diversity of important biochemical effects and pharmacological properties. A series of β-carboline derivatives were synthesized from L-tryptophan through the Pictet-Spengler reaction and oxidation of K2Cr2O7 via sequential one-pot synthesis method. In vitro anti-bacterial, insecticidal, and cytotoxic activities of all synthesized compounds were investigated by the tablet diffusion, leaf disc, and MTT methods, respectively. Some of the compounds(1a, 1b, 1c and 1j) exhibited obvious anti-bacterial effects and some (1-3) had significant cytotoxic activities against tumor cells 3LL, MCF-7, BGC-823 and QGY-7701, with IC50 values of 7.79, 5.75, 3.53 and 4.02 μg/mL, respectively. No insecticidal activity against third stage instar larvae of Mythimnaseparata Walker were observed under the tested concentration.
Serum Carboxylated and Undercarboxylated Osteocalcin association with Coronary Atherosclerosis Disease and Cardiovascular Risk Markers in: Analysis of a Syrian Male Cohort
Authors: Eddin Shahrour Hosam , Al Fahom Sahar , Al Massarani Ghassan , Jawich Kenda , Rasheed AlSaadi Ahmad
Published: October 2022

Background: New assumption concerning association of osteocalcin and Vascular calcification has emerged in reaction to observations that the mechanism of vascular calcification resembles that of bone mineralization, thus linking bone and the vasculature. However, studies reported contrasting results about the association between osteocalcin and atherosclerosis. This study was designed to evaluate capacity relationships among different forms of circulating osteocalcin and cardiovascular risk markers in male with coronary atherosclerosis.
Methods: A cross-sectional study was conducted on 58 male patients, divided into two groups according to the severity of coronary artery disease (CAD), as determined by coronary angiography assessment: Early coronary atherosclerosis (ECA), n=20, patients with mild CAD (<50% stenosis in any major epicardial arteries), and late coronary atherosclerosis (LCA), n=38, patients with severe, multivessel CAD (>50% stenosis in at least one or more major epicardial arteries). The healthy control (HC) group included 26 healthy male subjects. Carboxylated (cOC) and ucOC were measured using ELISA technique. Results: We observed significantly lower ucOC levels in both stages of cardiovascular disease (CVD) (ECA and LCA) compared to the HC group (2.34±2.23 and 2.48±1.60 vs 6.65±1.78ng/mL, P<0.01). ucOC was inversely correlated with an increasing number of cardiovascular risk factors (CVRFs). Moreover, ucOC levels were markedly reduced in high-fasting plasma glucose (FPG) groups (IFG and T2DM-threshold level), compared to the normal FPG group (NG). cOC levels were higher in the IFG group, compared to the normal FPG group (8.50±4.76 vs 7.13±3.13ng/mL, p=0.008) possibly predicting such condition. Conclusions: In the present study, patients with coronary atherosclerosis, regardless of the onset of stenosis, showed lower ucOC levels which were inversely correlated with an increasing number of CVRFs. Moreover, ucOC levels were markedly reduced in high-FPG groups. Serum ucOC may be considered as a potential biomarker for coronary atherosclerosis disease and therefore its measurement may help to establish preventive and therapeutic approaches. Moreover, cOC may be associated with a high alert for diabetes at the IFG stage, but not when the disease progresses to diabetes.
Antibacterial efficacy of Lemon Grass Oil (Cymbopogon citratus) on the type of bacteria and its count in Dental Aerosols
Authors: Ditto Sharmin David , Revathi K. , Mahendra Jaideep , Anandhi D. , Arun M. , Vigila J. Jasmine
Published: October 2022

Dental aerosol disinfection should be considered as one of the most serious issues as they have very harmful microbial flora which could lead to multiple serious infections that commonly infect the operator, assistant, or the patients. Essential oils of nature like Lemon Grass have been proven recently to possess a greater action against gram-positive and gram-negative bacteria, Candida species, Streptococcus mutans, which are considered as the most prevalent oral microbial flora. Hence this study is aimed to determine the antibacterial effect of the Lemon Grass oil on dental aerosol bacteria around the dental unit during the dental procedure. Dental chairs with patients during treatment were included for the study where 5 agar plates with and without Lemon Grass oil application were placed in each chair at a distance of 1 – 1.5 m from the patient's mouth for 48hours and were incubated. Types of bacteria and its count were evaluated. Results showed significant contamination of bacteria in all plates without Lemon Grass oil application, whereas significant contamination was observed in all positive control plates. Lemon Grass represents an antibacterial source that can be as effective as modern medicine against pathogenic microorganisms especially the gram-positive and gram-negative bacteria which are usually present in dental aerosols.
Correlation between Toxoplasmosis and Vitamin D Deficiency in women
Authors: AL-Fakhar Suha A. , M. Ali Wifaq , A. Mohammed Khalil Ismail , Mohammed Ali Saad Hasan , Mousa Jinan M. , Qasim Hussein Israa
Published: October 2022

Background: Recently it has been noticed that toxoplasmosis played an important role in distressing women’s pregnancy through certain outcomes such as congenital abnormalities and abortions. The lack in Vitamin D may play role fragility of bones like; osteoporosis, and bone deformities. Objective: To evaluate the association between the lake in vitamin D and toxoplasmosis seropositivity in the women’s sera in the age of childbearing by applying ELISA method. Materials and Methods: 56 women, from Central Public Health Laboratories in Baghdad Province were selected in this study, their age range between (17-45) years. The individuals were diagnosed with BOH (Bad Obstetric History). Among 56 women infected (44)or not infected (12)with toxoplasmosis blood samples were collected from patients who visited Central Public Health Laboratories in Baghdad Province . IgG and IgM Abs Antibodies against Toxoplasma gondii were detected using minividas kit ) BioMerieux /France). Also vitamin D was detected using by ELISA microwells method (Monobind Inc. USA). Results: The results were considered as statistically significant (P=0.386), it shows no important difference between toxoplasmosis and the concentration of vitamin D3 in women with history of abortion or not. Conclusion: The toxoplasmosis rate in women in childbearing age was elevated, and the association between vitamin D deficiency and toxoplasmosis was not considerable.
Collagen Thickness and Density in BALB/c Mice Exposed to UVB Light after using Siam Weeds Cream (Chromolaena odorata L.)
Authors: Amir Tahir Karlina , Djawad Khairuddin , Sartini Sartini , Budiyanto Arief , Lalo Ahmad , Jalaluddin Syatirah , Indrisari Maulita , Syakri Syamsuri , Ismail Asrul , Khaerani Khaerani , Masri Anshari , A. Miskad Upik
Published: October 2022

Introduction: Ultraviolet B (UVB) radiation can cause damage to the skin's dermis layer, which can lead to collagen fragmentation. Damage to collagen generates wrinkles, which are a sign of aging. Objective: The purpose of this study was to determine how Siam Weeds cream (Chromolaena odorata L.) altered the thickness and density of collagen in the skin of BALB/c mice after UVB exposure. Methods: There were four groups of 24 BALB/c mice altogether: normal control, negative control (Cream Base with UVB), positive control (UVB), and treatment (C. odorata cream and UVB). Just before and after the mice were exposed to UVB at 500 mJ/cm2, the Siam Weeds cream formulation was applied at a concentration of 1%. Mice were slaughtered, and a back skin excisional biopsy was conducted to analyze collagen. Results: the treatment group differed significantly both in thickness and density of collagen against the positive control group and the negative control group (p<0.05) and There was no statistically significant difference between the treatment and normal control groups (p<0.05). Conclusion: A 1% dosage of C. odorata cream can improve the thickness and density of collagen in UVB-exposed mice's skin.
Analytical Method Development and Validation of Trimethylazanium containing Anti-leishmanial Phospholipid Drug Miltefosine by Liquid Chromatography Quadruple Tandem Mass Spectrometry (LC-ESI-MS/MS) API-2000
Authors: Mandal Pallab , Kundu Pradip , Chakraborty Soumya , Bera Rakesh , Chatterjee Nilendra , Poddar Sourav , Ghosh D.P. , Kumar Pal Tapan
Published: October 2022

The phosphocholine and phospholipid that is hexadecyl monoester of phosphocholine (alkyl phospholipid) is a miltefosine drug used to treat all types of leishmaniasis. It is a broad-spectrum antimicrobial, anti-leishmanial, anti-cancer phospholipid drug. It is used for the treatment of breast cancer and cutaneous metastasis. This present study of miltefosine was given to develop. It validated the analytical method by LC-MS/MS (API-2000). It will be applied to the estimation of miltefosine from its solubility sample, force degradation sample, dissolution sample, and impurity analysis. The calibration concentrations of miltefosine were 125, 250, 500, 1000, 2000, and 4000 ng/ml which accuracy was 90.903 – 109.077% and reported stability was 90.71- 97.99%, 92.04 – 98.02%, 90.00 – 95.52%, 89.72 – 98.54% for freeze-thaw, short term, benchtop, autosampler stability respectively. The developed method for determining and quantifying miltefosine in the sample was also validated as per the US-FDA and EMA guidelines. The validation parameters found within the specified regulatory limit, hence acceptable. The present method also has a short run time (6.00 min). The method is simple, specific, highly selective, sensitive, and reproducible.
Potential Test of Soy-yamghurt against Antidiabetic in male white rats (Rattus norvegicus) Streptozotocin induced
Authors: Handayani Tien Wahyu , Anggi Viani , Afrizal Afrizal , Magfirah Magfirah , tandi Joni
Published: October 2022

Background: Soy-yamghurt is a fermented product of soy and sweet potato juice made from the addition of lactic acid bacteria and is thought to have antioxidant abilities, function to repair pancreatic cells, and reduce blood glucose levels. Aim: This study aims to determine the potential of soy-yamghurt probiotic drinks to decrease blood glucose levels of male white rats (Rattus novergicus). Method: This study used 30 rats divided into six treatment groups, namely normal control (NaCMC), negative control (streptozotocin+NA CMC), positive control (streptozotocin+glibenclamide), treatment formula 1 (streptozotocin+sweet potato juice+ soybean juice (1:1), formula 2(streptozotocin+sweet potato juice+soybean juice (1:2)), and formula 3(streptozotocin+sweet potato juice+soybean juice (2:1)). Results: The results showed that the average blood glucose levels were normal control (100.4mg/dL), negative control (298.8mg/dL), positive control (81.2mg/dL), formula 1(178.4mg/dL), formula 2(108.0mg). /dL), formula 3(134.4mg/dL). Conclusion: soy-yamghurt affects reducing blood glucose levels with an effective formula, namely formula 2 by giving 3.4ml.