bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review on the Antimicrobial Properties of Mediterranean Wild Edible Plants: We Still Know Too Little about Them, but What We Do Know Makes Persistent Investigation Worthwhile
Authors: Cappelli Giulia , Mariani Francesca
Published: September 2021

(1) Introduction: Bacterial resistance to antibiotics is estimated to be the cause of a major number of deaths by 2050 if we do not find strategies to slow down the rise of drug resistance. Reviews on Mediterranean wild edible plants (MWEPs) with antimicrobial properties are scarce in the main databases (PubMed, Scopus, and WoS). Hence, we proceeded to conduct a new review of the studies on MWEPs. (2) Methods: We used ‘wild edible plant’ and ‘antimicrobial’ as keywords. Within this group, exclusion criteria were reviews, studies concerning non-Mediterranean plants or non-edible plants, studies on topics other than plants or containing no description of antimicrobial properties, or off-topic studies. (3) Results: Finally, out of the one hundred and ninety-two studies we had started with, we reviewed thirty-eight (19.8%) studies concerning the antimicrobial properties of seventy-four MWEPs species belonging to twenty-five Families. Fifty-seven (77%) species out of seventy-four proved to be antimicrobial, with a stringent threshold selection. (4) Conclusions: Studies are still very heterogeneous. We still know too little about MWEPs’ properties; however, what we already know strongly recommends carrying on investigation.
Amplification Refractory Mutation System (ARMS)-PCR for Waxy Sorghum Authentication with Single-Nucleotide Resolution
Authors: Zhu Xiaoying , Wu Minghua , Deng Ruijie , Rizwan Khan Mohammad , Deng Sha , Wang Xi , Busquets Rosa , Deng Wanyu , Luo Aimin
Published: September 2021

Waxy sorghum has greater economic value than wild sorghum in relation to their use in food processing and the brewing industry. Thus, the authentication of the waxy sorghum species is an important issue. Herein, a rapid and sensitive Authentication Amplification Refractory Mutation System-PCR (aARMS-PCR) method was employed to identify sorghum species via its ability to resolve single-nucleotide in genes. As a proof of concept, we chose a species of waxy sorghum containing the wxc mutation which is abundantly used in liquor brewing. The aARMS-PCR can distinguish non-wxc sorghum from wxc sorghum to guarantee identification of specific waxy sorghum species. It allowed to detect as low as 1% non-wxc sorghum in sorghum mixtures, which ar one of the most sensitive tools for food authentication. Due to its ability for resolving genes with single-nucleotide resolution and high sensitivity, aARMS-PCR may have wider applicability in monitoring food adulteration, offering a rapid food authenticity verification in the control of adulteration.
Evaluation of the Effects of Different Dietary Patterns on Breast Cancer: Monitoring Circulating Tumor Cells
Authors: Wang Xiuxiu , Liu Xiaoyu , Jia Zhenzhen , Zhang Yilun , Wang Shuo , Zhang Hongyan
Published: September 2021

The occurrence and development of breast cancer are closely related to dietary factors, especially dietary patterns. This study was to investigate the effects of dietary patterns on the process of tumor metastasis by in vivo circulating tumor cell (CTC) capture strategy and monitoring changes of CTC numbers in breast tumor mice model. Meanwhile, the effects of different dietary patterns on the development of lung metastases of breast cancer and the volume and weight of carcinoma in situ were investigated. In this study, the increase in the number of CTCs was significantly promoted by dietary patterns such as high-salt diet, high-sugar diet, and high-fat diet, while it was delayed by ketogenic diet, low-fat diet, low-protein diet, diet restriction, and Mediterranean diet. These results indicated that the in vivo capture and detection of CTCs provides a convenient method for real-time cancer metastasis monitoring, and through in-depth study of the effects of different dietary patterns on tumor growth and metastasis, it can expand a new horizon in future cancer treatments.
Nutritive Value of 11 Bee Pollen Samples from Major Floral Sources in Taiwan
Authors: Hsu Pei-Shou , Wu Tzu-Hsien , Huang Meng-Yuan , Wang Dun-Yan , Wu Ming-Cheng
Published: September 2021

Bee pollen is a nutrient-rich food that meets the nutritional requirements of honey bees and supports human health. This study aimed to provide nutritive composition data for 11 popular bee pollen samples (Brassica napus (Bn), Bidens pilosa var. radiata (Bp), Camellia sinensis (Cs), Fraxinus griffithii (Fg), Prunus mume (Pm), Rhus chinensis var. roxburghii (Rc), Bombax ceiba (Bc), Hylocereus costaricensis (Hc), Liquidambar formosana (Lf), Nelumbo nucifera (Nn), and Zea mays (Zm)) in Taiwan for the global bee pollen database. Macronutrients, such as carbohydrates, proteins, and lipids, were analyzed, which revealed that Bp had the highest carbohydrate content of 78.8 g/100 g dry mass, Bc had the highest protein content of 32.2 g/100 g dry mass, and Hc had the highest lipid content of 8.8 g/100 g dry mass. Only the bee pollen Hc completely met the minimum requirements of essential amino acids for bees and humans, and the other bee pollen samples contained at least 1–3 different limiting essential amino acids, i.e., methionine, tryptophan, histidine, valine, and isoleucine. Regarding the fatty acid profile of bee pollen samples, palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), and linolenic acid (C18:3) were predominant fatty acids that accounted for 66.0–97.4% of total fatty acids. These data serve as an indicator of the nutritional quality and value of the 11 bee pollen samples.
Design of an In Vitro Model to Screen the Chemical Reactivity Induced by Polyphenols and Vitamins during Digestion: An Application to Processed Meat
Authors: Keuleyan Eléna , Bonifacie Aline , Gatellier Philippe , Ferreira Claude , Blinet Sylvie , Promeyrat Aurélie , Nassy Gilles , Santé-Lhoutellier Véronique , Théron Laëtitia
Published: September 2021

Processed meats’ nutritional quality may be enhanced by bioactive vegetable molecules, by preventing the synthesis of nitrosamines from N-nitrosation, and harmful aldehydes from lipid oxidation, through their reformulation. Both reactions occur during digestion. The precise effect of these molecules during processed meats’ digestion must be deepened to wisely select the most efficient vegetable compounds. The aim of this study was to design an in vitro experimental method, allowing to foresee polyphenols and vitamins’ effects on the chemical reactivity linked to processed meats’ digestion. The method measured the modulation of end products formation (specific nitroso-tryptophan and thiobarbituric acid reactive substances (TBARS)), by differential UV-visible spectrophotometry, according to the presence or not of phenolic compounds (chlorogenic acid, rutin, naringin, naringenin) or vitamins (ascorbic acid and trolox). The reactional medium was supported by an oil in water emulsion mimicking the physico-chemical environment of the gastric compartment. The model was optimized to uphold the reactions in a stable and simplified model featuring processed meat composition. Rutin, chlorogenic acid, naringin, and naringenin significantly inhibited lipid oxidation. N-nitrosation was inhibited by the presence of lipids and ascorbate. This methodology paves the way for an accurate selection of molecules within the framework of processed meat products reformulation.
Machine Learning Modeling from Omics Data as Prospective Tool for Improvement of Inflammatory Bowel Disease Diagnosis and Clinical Classifications
Authors: Stankovic Biljana , Kotur Nikola , Nikcevic Gordana , Gasic Vladimir , Zukic Branka , Pavlovic Sonja
Published: September 2021

Research of inflammatory bowel disease (IBD) has identified numerous molecular players involved in the disease development. Even so, the understanding of IBD is incomplete, while disease treatment is still far from the precision medicine. Reliable diagnostic and prognostic biomarkers in IBD are limited which may reduce efficient therapeutic outcomes. High-throughput technologies and artificial intelligence emerged as powerful tools in search of unrevealed molecular patterns that could give important insights into IBD pathogenesis and help to address unmet clinical needs. Machine learning, a subtype of artificial intelligence, uses complex mathematical algorithms to learn from existing data in order to predict future outcomes. The scientific community has been increasingly employing machine learning for the prediction of IBD outcomes from comprehensive patient data-clinical records, genomic, transcriptomic, proteomic, metagenomic, and other IBD relevant omics data. This review aims to present fundamental principles behind machine learning modeling and its current application in IBD research with the focus on studies that explored genomic and transcriptomic data. We described different strategies used for dealing with omics data and outlined the best-performing methods. Before being translated into clinical settings, the developed machine learning models should be tested in independent prospective studies as well as randomized controlled trials.
Genetic Variants and Somatic Alterations Associated with MITF-E318K Germline Mutation in Melanoma Patients
Authors: Vergani Elisabetta , Frigerio Simona , Dugo Matteo , Devecchi Andrea , Feltrin Erika , De Cecco Loris , Vallacchi Viviana , Cossa Mara , Di Guardo Lorenza , Manoukian Siranoush , Peissel Bernard , Ferrari Andrea , Gallino Gianfrancesco , Maurichi Andrea , Rivoltini Licia , Sensi Marialuisa , Rodolfo Monica
Published: September 2021

The MITF-E318K variant has been implicated in genetic predisposition to cutaneous melanoma. We addressed the occurrence of MITF-E318K and its association with germline status of CDKN2A and MC1R genes in a hospital-based series of 248 melanoma patients including cohorts of multiple, familial, pediatric, sporadic and melanoma associated with other tumors. Seven MITF-E318K carriers were identified, spanning every group except the pediatric patients. Three carriers showed mutated CDKN2A, five displayed MC1R variants, while the sporadic carrier revealed no variants. Germline/tumor whole exome sequencing for this carrier revealed germline variants of unknown significance in ATM and FANCI genes and, in four BRAF-V600E metastases, somatic loss of the MITF wild-type allele, amplification of MITF-E318K and deletion of a 9p21.3 chromosomal region including CDKN2A and MTAP. In silico analysis of tumors from MITF-E318K melanoma carriers in the TCGA Pan-Cancer-Atlas dataset confirmed the association with BRAF mutation and 9p21.3 deletion revealing a common genetic pattern. MTAP was the gene deleted at homozygous level in the highest number of patients. These results support the utility of both germline and tumor genome analysis to define tumor groups providing enhanced information for clinical strategies and highlight the importance of melanoma prevention programs for MITF-E318K patients.
Effects of Adherence to Pharmacological Treatment on the Recovery of Patients with Schizophrenia
Authors: Caqueo-Urízar Alejandra , Urzúa Alfonso , Mena-Chamorro Patricio , Bravo de la Fuente Josefa
Published: September 2021

The aim of this study was to evaluate the effects of adherence to antipsychotic treatment on the recovery of patients with schizophrenia in northern Chile. One hundred and fifty-one patients diagnosed with schizophrenia completed the Drug Attitude Inventory (DAI-10), Positive and Negative Syndrome Scale for Schizophrenia (PANSS), Recovery Assessment Scale (RAS-24), sociodemographic information, and clinical and treatment characteristics of patients with schizophrenia. Multivariate analysis with multiple linear regression was then performed to identify variables that were potentially associated with the recovery assessment (variable criterion). A significant association was found between adherence to antipsychotic medication and the Willing to Ask for Help dimension of Recovery (β = 0.239, p = 0.005). Association of clinical and socio-demographic variables with recovery were identified: negative symptoms with Personal Confidence and Hope (β = −0.341, p = 0.001) and Goal and Success Orientation (β = −0.266, p = 0.014); cognitive symptoms with Willing to Ask for Help (β = −0.305, p = 0.018) and no domination by symptoms (β = −0.351, p = 0.005); marital status with reliance on others (β = −0.181, p = 0.045); age with Personal Confidence and Hope (β = −0.217, p = 0.021), Goal and Success Orientation (β = −0.296, p = 0.003), and no domination by symptoms (β = 0.214, p = 0.025). Adherence has a positive relationship with personal recovery in this sample of Chilean patients with schizophrenia.
Research on the Impact of the Built Environment on the Characteristics of Metropolis Rail Transit School Commuting—Take Wuhan as an Example
Authors: Peng Jiandong , Qi Jiajie , Cui Changwei , Yan Jinming , Dai Qi , Yang Hong
Published: September 2021

The long-distance commute to school caused by urban sprawl and the car-oriented urban construction model are key factors leading to primary/middle school students being picked up by their parents in cars. Encouraging those students to take rail transit can reduce their dependence on cars. This paper uses a stepwise regression based on rail-transit swipe data to explore the influence of the built environment on rail-transit commuting characteristics in Wuhan, and uses a geographically weighted regression (GWR) model to analyze the spatial heterogeneity of significant influencing variables. The study found that: (1) 60% of students are one-way commuters; (2) 88.6% of students travel less than 10 km; (3) the floor area ratio, bus station density and whether the station is a transfer station have an obvious positive effect on the flow of commuters; (4) whether the station is a departure station has a positive effect on the commuting distance, but the mixed degree of land use and road density have a negative effect on the commuting distance. This research can assist cities in formulating built environment optimization measures and related policies to improve school-age children’s use of rail transit. This is important in the development of child-friendly cities.
Open Innovation Competence for a Future-Proof Workforce: A Comparative Study from Four European Universities
Authors: McPhillips Marita , Licznerska Magdalena
Published: September 2021

Digital transformation is a key driving force of open innovation to capture and transfer knowledge inside and outside of a company’s bounds. New challenges in organizing multiple knowledge flows imply the need for increased competences related to this paradigm of future employees. In this article, we organize and aggregate the competencies required for open innovation collaboration and develop a competence profile that organizes individual competencies in an open innovation context. Based on elements of the European Entrepreneurship Competence Framework, we delineate an OI Competence Profile and list the core competencies to manage and accelerate the inflow and outflow of knowledge. We explore this profile by comparing data from 2332 students from four European universities to find differences in the distribution of OI competencies between countries. The study contributes to understanding the individual competencies that target the future OI needs of companies necessary in the context of digital transformation. It also introduces an interdisciplinary approach to integrate the research streams of management practice, open innovation, and entrepreneurial education.
Some aspects of fishery development of sturgeon hybrids in Russia. Part 1
Authors:   Branch for Freshwater Fisheries of the  “VNIRO” (VNIIPRH), Russia, Melchenkov Evgeny Alekseevich , Myshkin Aleksey Vladimirovich ,   Branch for Freshwater Fisheries of the Federal State Budgetary Institution “VNIRO” (VNIIPRH), Russia, Kalmykova Vera Veniaminovna , Vorob’yov Aleksandr Pavlovich ,   Branch for Freshwater Fisheries of the Federal State Budgetary Institution “VNIRO” (VNIIPRH), Russia, Archibasov Arthur Alekseevich
Published: September 2021

With the development of commercial sturgeon breeding, creating hybrid forms of sturgeon fish in order to obtain a larger volume of gourmet marketable products is of increasing interest to fish farmers. The choice of objects for creating hybrid forms for commercial cultivation depends on the conditions and biotechnologies of intensive fish culture. One of the widely used technologies that can several times reduce the time for growing objects and receive viable juveniles and marketable products year-round is the technology using recirculating aquaculture system (RAS). With this cultivation technique, the advantage is given to species with high adaptive capabilities and growth intensity. The most popular objects for hybridization and creation of hybrid forms are beluga, sterlet, Siberian and Russian sturgeon, etc. Beluga is the largest representative of the sturgeon family. It reaches commodity weight (3–5 kg) against the background of natural temperatures within 2–3 years. The Sterlet is a pure freshwater form. It is an excellent object for cross-breeding with other sturgeon species, in particular with beluga to obtain a bester hybrid. The Siberian sturgeon grows most intensively at a temperature of 15–25 °C, however, the growth persists at lower temperatures (1–10 °C). The Russian sturgeon in artificial conditions reaches a marketable weight of 1.5–3.0 kg in the second-third years of cultivation. In order to facilitate the orientation of fish farms, fish farmers engaged in the production of commercial products, the article discusses the creation of hybrid forms of sturgeon fish in domestic and foreign aquaculture, provides their brief fish-breeding and biological characteristics when grown in fish farms of various types. Knowledge of the fish-breeding and biological characteristics of sturgeon fish species hybrids when grown in specific conditions will make it possible to successfully introduce them into the practice of commercial cultivation.
All-Russian research Institute of integrated fish farming-branch Of the Federal Science Center for Animal Husbandry named after Academy Member L.K. Ernst, Russia
Authors:   Russian Federal Research Institute of Fisheries and Oceanography, Senior Researcher, Department of Invertebrate Zoology, Lomonosov Moscow State University, Gordeev Ilya Ivanovich , Balabanova Lyudmila Vasilievna , Suvorova Tatyana Alexandrovna ,   Institute of Biology of Inland Waters named after I.D. Papanin RAS, Mikryakov Daniil Veniaminovich ,   Institute of Biology of Inland Waters named after I.D. Papanin RAS, Kuzmicheva Svetlana Vladimirovna ,   Institute of Biology of Inland Waters named after I.D. Papanin RAS
Published: September 2021

The composition of leukocytes reflects the species features of fish. The ratio of individual cell types reflects the functional state of the organism and the nature of the influence of biotic and abiotic stress factors. Kronotskoye Lake is located in the Far East on the territory of the Kronotsky State Natural Biosphere Reserve (Kamchatka). Due to the peculiarities of the hydrological regime and the relief of the Kronotskaya River basin, anadromous migration along it is limited. Therefore, anadromous fish do not return to the lake after the marine period of their life cycle. The lake basin is inhabited by at least six reproductively isolated forms (species) of chars. White char, Salvelinus albus Glubokovsky, 1977, at the early stages of ontogenesis feeds on invertebrates, and as it grows up, it goes on to a predatory lifestyle. White char migrates around the lake: spawning occurs in the tributaries, and feeding takes place in the lake itself. This work is devoted to the study of the intensity of leukopoiesis and leukocyte composition of the blood, head kidney and spleen of the white char of Lake Kronotskoye. Seven individuals caught using gill nets from July 8 to August 14, 2011 were studied. Peripheral blood was sampled from the tail vein. Sampling also included spleen and head kidney tissues, blood smears and organ-imprinted smears of kidney and spleen. The leukocyte formula and the frequency of occurrence of leukocytes in a peripheral blood smears were calculated using light microscope. The composition of white blood cells in the white char is similar to that of other fish species (lymphocytes, monocytes, neutrophils, and blast cell forms). No basophils or eosinophils were found. In organ-imprinted smears of immunocompetent organs (kidney, spleen), the percentage of lymphocytes is lower and the percentage of blast forms is higher than in the blood leukogram. The abundance index differed from the data obtained in the study of other fish species. English version of the article is available at URL:https://panor.ru/articles/composition-of-peripheral-blood-leukocytes-and-immunocompetent-organs-of-the-white-char-of-lake-kronotskoye-kamchatka/72718.html
The prospects for the development of blockchain technology in the NFT format
Authors: Zagidullin Daniyal Rashidovich , Pulyavina Nataliya Sergeevna
Published: September 2021

This article discusses the blockchain technology and a relatively new phenomenon in the field of this technology — NFT (non-fungible tokens). The paper analyzes the growth prospects and current shortcomings of the concept. The phenomenon of NFT, which is still not well described in scientific publications, is considered in this article from a technological point of view. Based on the results of the market analysis, the authors suggest continuing the development of the blockchain and strengthening its security, as well as conducting further research in this area.
Challenges and opportunities for scaling up infection prevention and control programmes in rural district hospitals of Tamil Nadu, India
Authors: Guhan Maya , Kumar Mohan , Butzin-Dozier Zachary , Graham Jay
Published: September 2021

Introduction: The aim of this study was to explore the barriers to implementing an infection prevention and control (IPC) programme in three public district hospitals in Tamil Nadu by interviewing key stakeholders involved in the roll-out of the programme. Materials and methods: Investigators conducted interviews (n = 17) with chief medical officers (CMOs), physicians, and IPC nurses at three secondary public district hospitals and their affiliated primary health centres (PHCs). Results: Six major themes emerged from the interviews: (1) prevalent IPC practices before the programme began; (2) barriers to implementation; (3) perceptions of the effectiveness of the IPC programme; (4) suggestions for future expansion of the programme; (5) the role of healthcare sanitation workers, and (6) water, sanitation and hygiene (WaSH) infrastructure. Stakeholders noted improvements in IPC knowledge, infection control related behaviour, and overall healthcare quality in the three hospitals. In regards to the future of this programme, stakeholders noted the need for more institutional support, a staff nurse solely dedicated to IPC, and the continued training of all staff members. Discussion: The results of this study highlight the importance of having high-functioning WaSH infrastructure and training for hospital sanitary workers in order to have an effective IPC programme. While the scale-up of this IPC programme is warranted, the barriers to implementation outlined in this study should be considered. To achieve a more effective IPC programme, we suggest that the following steps be carried out: (1) dedicate at least one full-time nurse to implementing IPC activities at each district hospital; (2) ensure that state and national policies for IPC are synchronised, and (3) provide sufficient and consistent funding for IPC activities.
HIDROFORMILACIÓN EN FASE HOMOGÉNEA DE EUGENOL E ISOEUGENOL CON LOS COMPLEJOS (RhCl(n4-1,5-COD)(2-ampy)) y (RhCl(PPh3)2(2-ampy)2)
Authors: Cuenu-Cabezas Femando , Duque-Hoyos Maria Cristina , Bolaños-Rivera Alberto
Published: September 2021

Se realizó la síntesis de los complejos (RhCl(n4-1,5-COD)(2-ampy)) y (RhCl(PPh3)2(2-ampy)2), (donde COD es ciclaoctadieno, 2-ampy es 2-ominopiridino y PPh3 trifenilfosfino). El compuesto (RhCl(PPh 3)2(2-ampy)2) presento un doblete a 29.4 ppm, con una constante de acoplamiento Rh-P de 86 Hz, indicando que las fosfinas se encuentran en posición trans. Los compuestos fueron activos en Ja hidroformilación de eugenol e isoeugenol, en donde la selectividad y actividad catalítica depende de varios factores tales como, los impedimentos estéricos en el ligante, los factores electrónicos y la temperatura de reacción. El complejo con los ligantes fosfina presento una menor actividad catalítica pero una mayor selectividad hacia aldehídos lineales.
CORRECCIÓN DE RUIDO TEMPORAL Y ESPACIAL ORIENTADO A LA MAXIMIZACIÓN DE CONTRASTE Y COMPENSACIÓN DE ILUMINACIÓN EN IMÁGENES INFRARROJAS
Authors: Jaramillo-I Alejandro , Padilla-B José Bestier , Arango Ramiro
Published: September 2021

Las imágenes infrarrojas presentan defectos asociados al hardware, como son: píxeles defectuosos, ruido temporal, ruido espacial, vignetting entre otros; e inherentes al medio como cambios de iluminación, corrientes de convección y conducción. En este trabajo se hace uso de metodologías enfocadas en la corrección de no uniformidades como lo es el algoritmo de las estadísticas constantes (CS) y rango constante (CR), así mismo se utiliza la morfología matemática y mapeos de contraste (MC) con el objetivo de maximizar el contraste y compensar los cambios de iluminación de cada uno de los frames infrarrojos.

Las métricas utilizadas para evaluar el desempeño de las técnicas corresponden al RMSE (error cuadrático medio) y al índice de merito Rho el cual es un estimativo de la cantidad de ruido eliminado, los resultados obtenidos con la utilización de las técnicas de corrección de no uniformidades presentan un índice de merito Rho y un RMSE bajo en comparación a los valores de estas métricas para frames contaminados, siendo estos cercanos a valores de las métricas obtenidos para un frame sin ruido espacial, aun, mejores resultados se obtienen cuando se aplican los operadores morfológicos y mapeos de contraste a las secuencias de imágenes provenientes de la etapa de corrección de ruido, dado que el contraste de la imagen es mejorado adaptativamente.
THE INFLUENCE OF SERVICE QUALITY ON CUSTOMER TRUST THROUGH VARIABLES INTERVENING CUSTOMER SATISFACTION USING STRUCTURAL EQUATION MODELING METHOD IN PT.XYZ
Authors: Sari Santika , Almaidani Adella Nurha , - Nurfajriah , Zaman Akhmad Nidhomuz
Published: September 2021

In companies engaged in the service sector, of course it cannot be separated from consumers, the need for food and customer satisfaction. Customer satisfaction at PT. PT. XYZis also the orientation of the company. However, in this newly established company, there are no orders that satisfy customers, so they can assess what factors cause customer satisfaction and what factors or things can be related to Customer Satisfaction. The things that have an influence on service quality are customer trust and reliability of service quality. Using structural equation modeling methods can make it easier to see the value or influence between variables. From this result, it can help evaluation if the three variables have a positive or good effect. Then the company needs to make a strategy to increase customer satisfaction. The results of this study found that the involvement of service quality has a positive and significant effect on customer satisfaction because the higher the involvement of service quality obtained, the higher the level of customer satisfaction in the company. In addition, it is also concluded that service quality and customer satisfaction are correlated so that it has a positive influence on customer trust.
PERANCANGAN ALAT PENGUPAS SABUT KELAPA MENGGUNAKAN METODE VDI 2221
Authors: Prima Febri
Published: September 2021

The increasing demand for coconut productin in Sungai Kupah Village, Kuburaya Regency has resulted in workers needing a tool that can complete work more quickly and effiently. The tools used today stil use wedges where their use takes a long tie because the process in the process relies on human power. In additin, with non-ergonomic work positins, workers can also experience several work-related diseases such as back pain and back pain. The objecties of this research are (1) Designing an ergonomic coconut peeler according to consumer needs (2) Testig the performance of the tool (3) Testig worker fatiue before and aftr using the tool (4) Testig the level of consumer satifactin. The solutin used in this study is the VDI 2221, CVL method approach, measuring tool  performance and analyzing the level of satifactin. The results obtained in this study are (1) produce a tool design according to consumer needs and have paid attntin to ergonomic aspects (2) The design of this tool produces a fairly fast stripping tie of 143 peeling fruit/hour when compared to tools using a wedge, namely 92 peeling fruit/hour (3) Worker fatiue test aftr using this tool showed 14.42 % of coconut owners, 11.20 % of worker 1 and 10.48 % of worker 2. This test resulted in CVL below 30% where workers did not experience fatiue. (4) Respondents feel comfortable with the designed tool as evidenced by the results of the 4.8 Linkert scale. Meanwhile, for ease of operatin, the result is 4.3, which means that respondents fid it easy to operate the designed tool. The conclusion in this study is that the currently designed tools are quite effctie, ergonomic and able to reduce the level of worker fatiue.
Floodplain Geomorphology and Response to Hurricanes: Lower Pee Dee Basin, South Carolina
Authors: Williams Thomas , Song Bo , Hitchcock Daniel , O'Halloran Thomas
Published: September 2021

Undeveloped forested wetlands in the valleys of coastal plain rivers can play a large role in storing floodwater and attenuating river flooding. In the lower Pee Dee, Little Pee Dee, and Lynches Rivers, these wetlands played a large role in mitigating downstream flooding following Hurricane Florence. Wetland forest flood mitigation was most effective for large flows in the Great Pee Dee River, where flooding on former river terraces determined the course of overbank flow and the potential storage of floodwaters. Floodwater storage and attenuation of water level were less effective if larger flows were limited to the Little Pee Dee River. Large rains prior to Hurricane Matthew, and to a lesser extent Tropical Storm Bertha, caused the forested wetland to be a source of additional flow, although with little increase in peak stage.
LUDICIDADE NO PIBID: UMA ANÁLISE SOBRE O USO DE JOGOS COMO RECURSO DIDÁTICO PARA APRENDIZAGEM DE MATEMÁTICA
Authors: Souza Jamile dos Santos , Santana Joalisson Bahia , Santos Daniela Batista
Published: September 2021

O Programa Institucional de Bolsas de Iniciação à Docência (PIBID), surge como um meio de inserir o licenciando em um ambiente escolar, para adquirir experiências enquanto discentes, que fortalecerão sua prática durante o curso e quando docentes. Afim de apresentar aos alunos uma matemática prazerosa, dinâmica e significativa, são desenvolvidas e utilizadas no PIBID, atividades e recursos didáticos diversificados e com potencial lúdico, com destaque para o uso de jogos. Nesse artigo, objetivamos refletir sobre as potencialidades de jogos para a aprendizagem de Matemática. Para tanto, analisamos dois jogos aplicados no PIBID no ano de 2017, a saber: Jogo da Memória com Números Ordinais e Jogo dos Cartões de Polinômios. Essas atividades buscaram desenvolver no aluno o interesse pela Matemática, bem como auxiliá-lo no processo de aprendizagem dos conceitos abordados, buscando trabalhá-los de forma dinâmica e prazerosa. Percebemos que os jogos apresentados trouxeram contribuições relevantes para a compreensão dos números ordinais e de polinômios, pois serviram como um meio de exercitar os conteúdos trabalhados em sala de forma lúdica. Destacamos também, que o jogo se revela como um recurso inovador e com potencial lúdico, com o qual pode-se romper com o ensino pragmático e mecânico da Matemática.
DIGITAL SPACE AS A MEANS OF STUDENT COMMUNICATION
Authors: Belyanskaya Tatiyana
Published: September 2021

This article discusses the concept of "digital space". The positive and negative aspects of the influence of this phenomenon on modern students are noted.
RISKS OF THE DIGITALIZATION OF EDUCATION OF ADOLESCENTS
Authors:   Voronezh State Pedagogical University, Pushkinа T.F. , Pushkin A.S. ,   Voronezh State Pedagogical University
Published: September 2021

The article examines the problems of psychological safety of a teenager's personality in the context of digitalization of education. The authors cite the data of an empirical study of schoolchildren on the risks of "information redundancy", "depersonalization" and virtualization of communication.
CYBERBULLYING IN THE TEENAGE ENVIRONMENT
Authors:   Voronezh State University of Forestry and Technologies Named after G.F. Morozov, Tregubova A.S.
Published: September 2021

In the modern world, where technological advances are taking violence to a new level, new ways of offending, humiliating, and harassing have emerged. This article examines one of the main threats that teenagers may face in the Internet space- "cyberbullying": the history of its appearance, the methodology of research, possible measures to counteract and prevent it.
Kaliningrad and Cultural Memory: Cold War and Post-Soviet Representations of a Resettled City
Authors: Saunders Edward
Published: September 2021

Book Review
Ornament und Mode bei Kafka, Broch und Musil. Literatur- und kulturwissenschaftliche Perspektiven auf das Fin de Siècle in Wien
Authors: Jones N.D.
Published: September 2021

Book Review
Pina Bausch und das Tanztheater: Die Kunst des Übersetzens
Authors: Paul Katherine H.
Published: September 2021

Book Review
IMPORTÂNCIA DA ASSISTÊNCIA DA TERAPIA OCUPACIONAL AO CUIDADOR DE CRIANÇAS COM CÂNCER EM CUIDADOS PALIATIVOS
Authors: SILVA DE OLIVEIRA DE SOUZA VIVIAN
Published: September 2021

Cancer has a great possibility of cure, however there is a group of patients who can reach the critical stage and no longer respond to conventional therapies, making it impossible to obtain a cure. In such cases, it will be necessary to provide other types of care in order to provide support, information and comfort to patients in the final stage of life and their families, which characterizes Palliative Care. In pediatrics, palliative care is centered on the child and the family. This study aimed to conduct a literature review on the intervention of Occupational Therapy with caregivers of children in Palliative Care, due to childhood and juvenile cancer. We searched for articles that corresponded to the descriptors that could support this study, however the search resulted in only two articles, a factor that made the study turn to a bibliographic search. Despite the reduced number of articles on occupational therapy in caring for children in palliative care, this study made it possible to present the importance of the attention and contribution of Occupational Therapy in caring for caregivers of children in the final stage of life.
ASSÉDIO MORAL : UM OLHAR PARA SAÚDE MENTAL DO TRABALHADOR
Authors: Souza de Oliveira Fernanda , Silva Boabaid Jesuino , Magalhães de Morais Uérle
Published: September 2021

Moral harassment is a complex phenomenon and a reality faced in the workplace, it is a type of abuse that involves ethical principles, which can compromise the quality of life of workers, leading them to diseases and suffering in the workplace. This study describes a systematic bibliographic review search, using the following descriptors: "mental health of the worker", "moral harassment at work" and "health psychology". The results presented show that the consequences of bullying have been of great interest to several researchers, and that in general it involves some damage to safety and health at work and not only the individual issue of mental health. It is hoped that this study can contribute to reflections and debates about the impact of moral harassment on workers' health, allowing visibility of a theme that is little addressed and conveyed in the work environments themselves.
Regulation of Suspended Matter Concentration in Bed-diverting Channels during their Commissioning. Statement 1. Problems Arising in the Use of the Known Calculation Methods for Water Consumption in Bed-diverting Channels
Authors:   Kosarev S.G.
Published: September 2021

The statement considers the use of step-by-step washing of bed-diverting channels as one of the methods of natural water bodies protection against pollution with suspended matter. The current methods of water flow designation in bed-diverting channels in the step-by-step washing have been assessed, the drawbacks of these methods have been noted, the tasks of further investigations on their improvement have been set, this will allow to provide correspondence to the norms of maximalpermissible discharge of suspended matter to watrer bodies for bed-diverting channels of various purposes made in loose soils.
Hydrological Regime of the Trans-Baikal Lakes in the conditions of the Changing Climate (Ivano-Arakhleysky Lakes as a Study Case)
Authors:   Obyazov V.A.
Published: September 2021

Long-term changes of temperature of air and atmospheric precipitation in Transbaikalia and their influence on the hydrological regime of the Ivano-Arahleysky lakes are considered in the article. Climate changes have caused rise in temperature of water of lakes, reduction a thickness of ice and duration of standing of ice. Water level fluctuations have cyclic character and depend on long-term changes of atmospheric precipitation.
Project on the Selenga River Basin Water Resources Management: Mechanism of Cooperation
Authors:   Gomboyev B.O., Zomonova E.M.
Published: September 2021

The article gives a brief description of a project on the Selenga River basin water resources management, a mechanism of cooperation, main outputs and lessons derived from the Project.
Regulation of Suspended Matter Concentration in Bed-diverting Channels during their Commissioning. Statement 2. Proposed Improvements of the Calculation Methods
Authors:   Kosarev S.G.
Published: September 2021

As a result of numerical experiment with triangle and trapezoidal (hydraulically the most favorable) forms of a channel cross section diameters of particles able to move in a flow in the suspended state at each stage of the channel washing and their mass have been determined. Dependence for water discharge setting in the bed-diverting channels during their commission that allow to regulate suspended matter concentration in watercourses within the preset values has been proposed.
Results of the Perm Sewage System Reconstruction. The Second Stage of Biological Treatment Reconstruction
Authors:   Kell O.A.
Published: September 2021

The results of the local authorities and a private operator «Expansion and reconstruction of the Perm sewage system» joint project are represented in this work. The reconstruction scheme of an aeration tank for nitri-denitrification technology is given. The analysis of aerated sand separations, primary and secondary sediment bowls, and aeration tank performance on removal of polluting substances is made. The waste waters treatment efficiency of the biological treatment facilities is shown.
Gender Income Differentials in Malaysia
Authors: Cheong Jia Qi , Narayanan Suresh
Published: September 2021

Studies related to distribution of income is very important for national development as it is related to efforts also to reducing the gender earnings disparity. Women have overcome many challenges within the labour market, but gender income differentials still persist in Malaysia. As reducing the gender income differentials is one of the ingredients for sustained economic growth, this article examines the gender income distribution in several submarkets within the Malaysian labour market and discusses some initiatives aimed at reducing income disparities therein

Keywords: Differentials; Gender; Income; Labour, Malaysia
Assessing Competency and Sub-Competency for Pharmaceutical 4.0 – a Delphi Study
Authors: Aliya Putri Aghnia Nadhira , Arief N. Nurlaela , Gustomo Aurik
Published: September 2021

In the Era of Industry 4.0, technology has a significant impact on how people live and work. The pharmaceutical sector is likely to face an "innovator dilemma" when dealing with the Fourth Industrial Revolution. Pharmaceutical employees should prepare to adopt technologies such as the Internet of Things (IoT), Artificial Intelligence (AI), Big Data, Robotic, 3-D printing (Baines et al., 2018). Even in the industry based on technology, companies' performance does not rely solely on technological expertise. Technology is not the most significant barrier to adopting the 4.0 Era, but organizational culture and employee readiness are the biggest challenges (Vuong et al., 2019). To survive in Industrial Era 4.0, having sufficient knowledge of technology's changes and speed is essential. Nevertheless, there is no doubt that specific low-skilled jobs will be eliminated (Dirican, 2015). Supposedly, the development of technology does not replace workers but instead increases efficiency in work. Note that the future workforce has a critical role to play in the success of factory innovation. Transformation in era 4.0 requires workforces to have good competence.

Keywords: Competency, Sub-Competencies, Pharma 4.0, Delphi Study
Ethics of scientific communication as a means of respect for readers
Authors: Kosycheva Marina A. , Tikhonova Elena V.
Published: September 2021

The ethics of scientific communication from the point of view of compliance with legal and moral norms, social responsibility and respect for the reader is analyzed. Forms of academic plagiarism are considered. One of the forms of hidden plagiarism - translation plagiarism - is described in detail. Attention is paid to methods of recognition of plagiarism in translation.
Chronic thromboembolic pulmonary hypertension: the impact of advances in perioperative techniques in patient outcomes*
Authors: Gobi Scudeller1 Paula , Terra-Filho1 Mario , Freitas Filho1 Orival , Regina Barbosa Gomes Galas2 Filomena , Dutra de Andrade1 Tiago , Odnicki Nicotari1 Daniela , Michelin Gobbo1 Laura , Antonio Gaiotto1 Fabio , Abrahão Hajjar1 Ludhmila , Biscegli Jatene1 Fabio
Published: September 2021

Objectives: Pulmonary endarterectomy (PEA) is the gold standard treatment for chronic thromboembolic pulmonary hypertension (CTEPH). This study aimed at reporting outcomes of CTEPH patients undergoing PEA within 10 years, focusing on advances in anesthetic and surgical techniques. Methods: We evaluated 102 patients who underwent PEA between January 2007 and May 2016 at the Instituto do Coração do Hospital das Clínicas da Universidade de São Paulo. Changes in techniques included longer cardiopulmonary bypass, heating, and cooling times and mean time of deep hypothermic circulatory arrest and shortened reperfusion time. Patients were stratified according to temporal changes in anesthetic and surgical techniques: group 1 (January 2007-December 2012), group 2 (January 2013-March 2015), and group 3 (April 2015-May 2016). Clinical outcomes were any occurrence of complications during hospitalization. Results: Groups 1, 2, and 3 included 38, 35, and 29 patients, respectively. Overall, 62.8% were women (mean age, 49.1 years), and 65.7% were in New York Heart Association functional class III-IV. Postoperative complications were less frequent in group 3 than in groups 1 and 2: surgical complications (10.3% vs. 34.2% vs. 31.4%, p=0.035), bleeding (10.3% vs. 31.5% vs. 25.7%, p=0.047), and stroke (0 vs. 13.2% vs. 0, p=0.01). Between 3 and 6 months post-discharge, 85% were in NYHA class I-II. Conclusion: Improvements in anesthetic and surgical procedures were associated with better outcomes in CTEPH patients undergoing PEA during the 10-year period.
PENDIDIKAN KELUARGA MENURUT SYAIKH NAWAWI DALAM KITAB UQÛD AL-LUJJAYN FÎ BAYÂNI HUQÛQ AL-ZAWJAIN
Authors: Muqoffi Muqoffi , Syarifah Masykurotus
Published: September 2021

Nowadays the tempest of the household not only raises acute disharmony between husband and wife but also has fatal consequences for the moral decadence of children. Therefore, it is felt necessary to examine family education in the book of Uqûd al-Lujjayn by Shaykh Nawawi to transmit objective steps in maintaining the stability of Islamic households to the community. This research is a type of literature study using a qualitative approach. From the results of the study, it was found that the purpose of family education is to care for the family from Hellfire with the approach of the science of jurisprudence and morals. Educators are fathers and mothers, while students are wives and children through the methods of instruction and habituation, question and answer, punishment and exemplary. The internalization of Shaykh Nawawi's family education is very relevant in modern families as a preventive measure from the threat of materialistic life style threats. Among them, optimizing the husband in playing his role as an educator for children and wife towards the inculcation of sharia values ​​and character education, not just fulfilling birth obligations. Likewise a mother establishes herself as a domestic worker and child educator. An ideal formulation of family education in realizing the quality of faith and piety not the quantity of thrones and possessions. But the concept of Shaykh Nawawi in intimidating children in giving orders needs to be synergized with typical modern children. For children who are hard-hearted, arrogant and egocentric, this concept is considered not accurate, so the relevance is not right. Likewise, direct punishment to children and wives is considered less relevant. Imposing punishment must be carried out procedurally with the principle of proportional and conditional sourced from the principle of min al-akhaffi ilâ al-asyad: starting from the lightest to the heaviest.
Mancha tipográfica
Authors: De Moraes Nastari Zeni Sílvia , Da Costa Braga Marcos
Published: September 2021

Entre os anos de 1941 e 1955 a Livraria Martins Editora, sediada em São Paulo, publicou a coleção Biblioteca de Literatura Brasileira, constituída por 15 volumes, que se define por publicar escritores consagrados pelo público e pela crítica, com introduções de estudiosos renomados e ter seus exemplares ilustrados por grandes nomes da arte brasileira ou da ilustração profissional. Os livros da coleção apresentam um projeto gráfico que se estrutura a partir de parâmetros clássicos de composição, sob a influência de edições francesas e inglesas. O objetivo deste artigo é identificar – a partir da análise do design dos livros, em específico da mancha tipográfica – como as edições empregam alguns padrões gráficos que permitem atribuir ao conjunto um caráter de coleção. O presente estudo também pretende propor instrumentos de análise para melhor compreender os parâmetros gráficos e editoriais adotados na BLB, bem como para coleções semelhantes.