bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Penerapan Metode Ceramah terhadap Pemahaman Siswa pada Pelajaran Sosiologi Kelas XII IPS 5 di SMAN 1 Pasaman
Authors: Aisya Rihadhatul , Wahyuni Yanti Sri , Hefni Hefni
Published: March 2023

This research was motivated by teachers at SMAN 1 Pasaman who taught in class XII social studies 5 using the lecture method in the learning process. Judging from the level of students' understanding of the material provided by teachers in Sociology subjects is still relatively low. This study aims to find out 1) an overview of the lecture method, 2) an overview of the level of understanding of students and 3) the influence of the application of the lecture method on the level of understanding of students. The theory used in this study is cognitivism, which emphasizes that a person's behavior is determined by the perception of his understanding of situations related to the purpose of learning. Types of descriptive quantitative research corelation. The population in the study were 34 students of class XII IPS 5 at SMAN 1 Pasaman. Sampling using total sampling technique. The instrument used for research was a closed questionnaire using the Pearson correlation test. The results showed that: (1) the lecture method was in the "Very High" category with a percentage of 67.6%, (2) the level of understanding was in the "Very High" category with a percentage of 70.6%, and (3) there was the relationship between the two variables is positive and significant between the lecture method (X) and the level of understanding (Y) of students with r count > r table, namely 0.906 > 0.338 and t count > t table, namely 2.036. The conclusion is that there is an influence between the two variables which is positive and significant between the lecture method and the level of understanding of students and it is suggested for academics to make the results of this study as teaching materials for sociology education students in applying the lecture method as a teaching method in sociology lessons.
The Analysis of Strategic Role of Student Association in Improving Discipline Attitude and Forming Quality of Graduates
Authors: Ashadi Firman , Supriatna Dasep , Haris Muhammad , Hasanah Uswatun , HinayatulohI Ahmad
Published: March 2023

The purpose of this research is to obtain data about the process of intra-school student organization activities. The spirit of discipline between administrators and members of intra-school student organizations; what are the obstacles to the implementation of the intra-school student organization program; efforts to increase discipline in intra-school student organizations; and how to overcome discipline and achieve student achievement. The method used in this research is a qualitative approach through stages of observation, interviews, and documentation studies. The objects of this study were the principal, the deputy head of student affairs, members of intra-school student organizations, and 10 students. Data analysis can be done through categorization, data reduction, validity testing, drawing conclusions, and data presentation. The results of the study show that intra-school organization activities play an important role in improving discipline and the quality of graduates through intra-school student organization work programs contained in the intra-school student organization structure and student achievement data.
Pelaksanaan Supervisi Akademik untuk Meningkatkan Kompetensi Guru dalam Menerapkan Model Pembelajaran Berbasis Teknologi di Sekolah Binaan SMPN 6 Tanjung Jabung Timur Semester Genap Tahun Ajaran 2021/2022
Authors: Jaliusril Jaliusril
Published: March 2023

This study aims to obtain information and discuss the implementation of academic supervision to increase teacher competency in implementing technology-based learning models in target schools of SMPN 6 Tanjung Jabung Timur even semester of the 2021/2022 academic year. This type of research is school action research. This research was conducted at SMPN 6 Tanjung Jabung Timur which is a school assisted by researchers as supervisors. This research schedule is carried out in the even semester of the 2021/2022 school year with 8 teachers as subjects. Data was collected through observation sheets, field notes, and documentation. Data analysis techniques use percentages and data reduction. Based on the results of the research and discussion, it can be concluded that through the implementation of academic supervision, it can increase teacher competence in applying technology-based learning models at SMPN 6 Tanjung Jabung Timur target schools in the even semester of the 2021/2022 school year. This can be seen from the increase in the teacher's ability to apply the learning model from cycle I to cycle II.
Analisis Kemampuan Berpikir Kritis Melalui Model Pembelajaran Problem Based Learning Kelas IV SDN Pandeanlamper 03 Kota Semarang
Authors: Jannah Lutnatul , Listyarini Ikha , Nugroho Aryo Andri , Saputro Susilo Adi
Published: March 2023

The independent curriculum's problem-based learning model promotes the development of a skill called critical thinking, which is necessary for learning in the twenty-first century. This study uses a model of problem-based learning to describe the critical thinking abilities of fourth grade students. Descriptive qualitative research is the method employed. 28 fourth-grade students at SDN Pandeanlamper 03 in Semarang City served as the study's participants. Data for the study were gathered from documentation, class teacher interviews, and observations. Data reduction, data presentation, and conclusion-drawing techniques are used when analyzing research data. Observations of critical thinking abilities in class IV students who have adopted the independent learning curriculum. Students engage in discussions and problem-solve while presenting issues connected to the material being taught in order to improve their critical thinking abilities.
Peningkatan Kompetensi Guru Menerapkan Model Pembelajaran Kooperatif Melalui Workshop di SDN 12/X Pemusiran Pada Semester Genap Tahun Ajaran 2021/2022
Authors: Suryani Lilis
Published: March 2023

This study aims to obtain information and discuss increasing teacher competence in applying the cooperative learning model through workshops at SDN 12/X Pemusiran in the even semester of the 2021/2022 academic year. This type of research is school action research. This research was conducted at SDN 12/X Pemusiran in the even semester of the 2021/2022 academic year. The research subjects were all teachers at SDN 12/X Pemusiran, totaling 5 people. Data was collected through observation sheets, field notes, and documentation. Data analysis techniques use percentages and data reduction. Implementation of workshops that focus on increasing teacher competence in applying cooperative learning models, has increased. Based on the results of the research, it can be concluded that through workshops it can increase teacher competence in implementing cooperative learning at SDN 12/X Pemusiran in the even semester of the 2021/2022 academic year.
Peningkatan Kemampuan Membaca Permulaan melalui Media Flash Card pada Siswa Kelas 1 SD di biMBA-Aiueo Kramat Semanan
Authors: Chaerani Annissa , Fadilah Ahmad Arif , Azhar Arry Patriasurya , Magdalena Ina , Sa’odah Sa’odah
Published: March 2023

This thesis is motivated by the low development of early reading skills in grade 1 elementary school students at biMBA-AIUEO Kramat Semanan. This study also aims to improve early reading skills using flash card media in pre-school age children. The subject of this study consisted of 13 children, 8 boys and 5 girls. This research is a classroom action research that uses the Kemmis and Mc Taggart research model while the data collection techniques used by observation, interviews, documentation and tests. The data analysis technique using quantitative descriptive percentage. The results shows that the early reading ability of children at biMBA-AIUEO Kramat Semanan improved gradually by using flash card media through the steps, namely, recognizing the relationship of letters to sounds, distinguishing letters/recognizing familiar letters, mentioning words with the same initial letters, combining syllables into words, mentioning pictures that have words, and reading words clearly. The improvement can be proven from the result of the first cycle research is in the criteria of developing as expected by 53%, then increase in cycle II to 80%, and increasing to 96.3% in the third cycle. From the description above, it can be concluded that using flash card media can improve early reading skills in pre-school age children at biMBA-AIUEO Kramat Semanan, Kalideres District, West Jakarta.
General Mile Novaković - the First Commander-in-chief of the Serbian Krajina Army
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Sokolov Vadim , Novakovic Кosta ,   Independent researcher
Published: March 2023

The author discusses the biography of General Mile Novaković, Commander-in-chief of the Army of the Serbian Krajina. Based on archival documents, the general's service in the Yugoslav People's Army, and his role in the war in Croatia are examined, particularly his actions during Operation “Storm”, where he led the rescue of a column of Serbian refugees.
Zoran Đinđić: Politician Shot at the Top of His Career
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Edemsky Andrey
Published: March 2023

The author reveals the main aspects of the life and work of Zoran Đinđić, the first Prime Minister of Serbia after the fall of the Milosevic regime, a politician of a complex and contradictory, but at the same time vivid, character and of substantial political actions. The researcher studies the main milestones of the politician's biography, including his student years; his activity in Yugoslavia as a representative of the younger generation of the last dissident wave during mature Titoism and the post-Tito transition period; his consistent transformation into an authoritative participant in the civil political opposition in the 1990s; and his reform activities. The author attempts to expose his relations with political opponents and allies, his views, and the methods of his struggle to achieve his goals.
Obiteljski odgoj promatran u »Bosiljku«, »Smilju« i »Bršljanu« – časopisima za djecu i mlade druge polovice 19. stoljeća u Hrvatskoj
Authors: Lenard Ivan , Lukaš Mirko
Published: March 2023

Obitelj zauzima važno odgojno i socijalizacijsko uporište za održanje društvene zajednice, a njezin povijesni diskurs nam omogućuje bolje razumijevanje suvremene problematike ovog fenomena. Analiza sadržaja u odabranim časopisima za djecu i mlade tijekom druge polovice 19. stoljeća u Hrvatskoj ilustrira praksu obiteljskog odgoja i tadašnje proklamirane obiteljske vrijednosti. U ovom su radu analizirani odabrani tekstovi časopisa »Bosiljak«, »Smilje« i »Bršljan« unutar 177 brojeva i otisnutih na 3.685 stranica. Hermeneutički pristup nam omogućuje zaključak da se u hrvatskoj pedagoškoj literaturi promatranog razdoblja obitelji prilazi kao primarnoj odgojnoj zajednici u kojoj je majka okosnica obiteljskog odgoja. Analiziranim sadržajima interpretiraju se obiteljske vrijednosti koje je moguće kategorizirati kao: ljubav prema majci, majčinska ljubav, ljubav prema sestri, ljubav prema roditeljima, ljubav prema djetetu, ljubav prema bratu i ljubav prema ocu. Provedeno istraživanje potvrđuje postojanje odgojnih vrijednosti u sadržajima časopisa za djecu i mlade u drugoj polovici 19. stoljeća i interes za podizanje pedagoške kulture roditelja u obiteljskom odgoju na promatranom hrvatskom prostoru.
Uloga izloženosti nasilju roditelja učenika u predviđanju zadovoljstva poslom osnovnoškolskih ravnatelja
Authors: Dragoslavić Marijana , Bilić Vesna
Published: March 2023

Rad ravnatelja škola uključuje raznovrsne poslove, a kao iznimno osjetljivo i zahtjevno područje može se izdvojiti suradnja s roditeljima učenika. U novije vrijeme na svom radnom mjestu ravnatelji su nerijetko izloženi različitim nedopustivim ponašanjima i nasilju roditelja, no o tome se malo zna i govori. Cilj je ovoga istraživanja ispitati ulogu izloženosti nasilju roditelja učenika u predviđanju zadovoljstva poslom ravnatelja osnovnih škola Republike Hrvatske. U istraživanju je sudjelovalo 483 (M = 27,7 %; Ž = 72,3 %) ravnatelja iz svih regija Republike Hrvatske, time je obuhvaćeno 52,6 % pripadnika ciljane populacije. Za prikupljanje podataka korišteni su Upitnik sociodemografskih karakteristika, Skala izloženosti nasilju roditelja te Upitnik zadovoljstva poslom. Rezultati pokazuju da je riječ o raširenoj pojavi, a 80,75 % ravnatelja je tijekom svog ravnateljskog staža doživjelo barem jedan oblik nasilja od strane roditelja. Korelacijskom analizom utvrđeno je da ravnatelji koji češće doživljavaju nasilje roditelja imaju nižu razinu zadovoljstva poslom, a regresijska analiza pokazala je da je doživljeno nasilje statistički značajan prediktor zadovoljstva poslom. Jasna osuda svih oblika nasilja roditelja nad ravnateljima te primjena i poboljšavanje postojećih propisa zaključno se izdvajaju kao nužni uvjeti za smanjivanje te negativne pojave i omogućavanje kvalitetnog rada ravnatelja, a time i škola u cjelini.
Causes of Ecological Crisis and the Necessity of Ecological Education in the Encyclical Laudato Si’
Authors: Bekavac Ante
Published: March 2023

The modern ecological crisis that today radically affects people and the nature reveals the deeper causes that lie within people themselves. First of all, people no longer understand themselves in the key of creation, they no longer understand themselves and the created world as gifts from the Creator, but are intoxicated with power combined with technology and science in the instrumental-rational key and understand themselves as the sole creators of their own fates. Relying on the hermeneutic key to understanding creation, Pope Francis starts from the Creator and exposes this crucial anthropological fallacy, the price of which has unforeseeable effects on the created reality. The paper points out the fundamental problems and difficulties of the modern ecological crisis, seeking to show that it is actually hidden in the crisis of the humanity. Following the contemplations and ideas that Pope Francis presented in the encyclical Laudato Si’, the paper seeks to highlight the neuralgic points of the contemporary ecological crisis by showing ways out of the labyrinth of anthropological self-sufficiency. The need for and importance of education for environmental awareness, i.e., a responsible, mature and moral approach to created reality, are emphasized. In the final part of the paper, the rapprochement to freedom is highlighted, in line with the human dignity that has its source in God the Creator. Answering the question of why ecological education is important and crucial, the conclusion shows that it is the only right path of authentic humanity that bears the mark of creation in God’s image, and that people are called to act responsibly towards the created reality.
Izrael – podrijetlo i nastanak naziva židovske države
Authors: Havel Boris
Published: March 2023

Naziv židovske države proglašene u Tel Avivu 14. svibnja 1948. do samoga je trenutka proglašenja bio nepoznat javnosti. Ime Izrael u povijesti Jišuva i sekularnog cionizma pojavljivalo se uglavnom u smislu Erec Izrael što je biblijski naziv koji se okvirno odnosi na područje Palestine. Drugdje u tekstovima vezanima za cionistički pokret, poput Herzlove raspravnice Der Judenstaat, rabila se sintagma »židovska država«, a u prvome važnom nežidovskom dokumentu, Balfourovoj deklaraciji iz 1917., »nacionalni dom židovskoga naroda«. Tek nakon što je David Ben-Gurion pročitao izraelsku Deklaraciju o nezavisnosti, naziv Izrael za novoosnovanu židovsku državu u Palestini postao je općepoznat. Premda nije bio očekivan, taj naziv ne samo da je odmah zaživio, nego je i među Židovima i među nežidovima shvaćen kao ime koje se podrazumijeva. U ovome je članku opisano povijesno značenje pojma Izrael, ponuđeno je objašnjenje njegove odsutnosti u cionističkom nazivlju prije trenutka proglašenja Države Izrael, te je predstavljena pretpostavka da je Ben-Gurion bio ključna osoba za nadijevanje imena novoosnovanoj židovskoj državi.
Differential expression of SLC22A3 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding solute carrier family 22 member 3, SLC22A3, when comparing colorectal tumors to the tissue of origin, the colon. SLC22A3 mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of SLC22A3 in rectal tumors was correlated with overall survival in patients with rectal cancer whose tumors were relatively depleted of CD8+ T cells. SLC22A3 expression changes may be important for the initiation or progression of human CRC.
Historical Consistent Neural Networks with pretraining and dynamic sparsity training
Authors: Hamster Ulf A.
Published: March 2023

The subject of this paper is the Historical Consistent Neural Networks (HCNN) model, a recurrent wide-shallow sparse neural network. We propose a pretraining routine to initialize sparse connections for recurrent HCNN models, implemented gradient-based regrowth with dormant weights for dynamic sparsity training, and propose a time-series sampling method to avoid overlapping segments in a training batch. For the experiments, we applied a many-to-one HCNN model on speed traffic data. Unfortunately, the dynamic sparsity training yields no benefit, at least during the first 100 epochs. However, pretraining the HCNN sparsity pattern improves convergence considerably. All sparse models converge, while the dense RNN baseline fails to do so.
Differential expression of LRRC8E in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding leucine rich repeat containing 8 family member E, LRRC8E, when comparing colorectal tumors to the tissue of origin, the colon. LRRC8E mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of LRRC8E in rectal tumors was correlated with overall survival in patients with rectal cancer whose tumors were relatively enriched with B cells. LRRC8E expression changes may be important for the initiation or progression of human CRC.
Differential expression of GUCA2B in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding guanylate cyclase activator 2B, GUCA2B, when comparing colorectal tumors to the tissue of origin, the colon. GUCA2B mRNA was present at significantly lower quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of GUCA2B in rectal tumors was correlated with overall survival in patients with rectal cancer with high mutational burden. We recently found differential expression of GUCA2A in human colorectal cancer (5). GUCA2B expression changes may be important for the initiation or progression of human CRC.
Differential expression of EPB41L3 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding erythrocyte membrane protein band 4.1 like 3, EPB41L3, when comparing colorectal tumors to the tissue of origin, the colon. EPB41L3 mRNA was present at significantly lower quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of EPB41L3 in rectal tumors was correlated with overall survival in patients with rectal cancer whose tumors were relatively depleted of CD8+ T cells. EPB41L3 expression changes may be important for the initiation or progression of human CRC.
Differential expression of C2orf88 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding chromosome 2 open reading frame 88, C2orf88, when comparing colorectal tumors to the tissue of origin, the colon. C2orf88 mRNA was present at significantly lower quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of C2orf88 in rectal tumors was correlated with overall survival in patients with rectal cancer with high mutational burden. C2orf88 expression changes may be important for the initiation or progression of human CRC.
Differential expression of NIFK in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding nucleolar protein interacting with the FHA domain of MKI67, NIFK, when comparing colorectal tumors to the tissue of origin, the colon. NIFK mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of NIFK in rectal tumors was correlated with overall survival in patients with rectal cancer. NIFK expression changes may be important for the initiation or progression of human CRC.
The effectiveness of allied health and emergency nurse practitioners’ managing musculoskeletal conditions in the emergency department: protocol for a systematic review and meta-analysis
Authors: Vella Simon Paul , Coombs Danielle , Melman Alla , Maher Christopher , Swain Michael , Monk Elizabeth , Topacio Michelle , Machado Gustavo C
Published: March 2023

The primary aim of this systematic review and meta-analysis is to evaluate the effectiveness of emergency nurse practitioners and allied health practitioners managing musculoskeletal conditions in ED. This review will provide insight toward effective strategies for managing MSK conditions in ED, highlight evidence gaps and update recommendations toward these health services. The preprint outlines the research plan including our search strategy and statistical analysis for our study.
Differential expression of PUS1 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding pseudouridylate synthase 1, PUS1, when comparing colorectal tumors to the tissue of origin, the colon. PUS1 mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of PUS1 in rectal tumors was correlated with overall survival in patients with stage II rectal cancer. PUS1 expression changes may be important for the progression of human CRC.
Differential expression of PPAT in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding phosphoribosyl pyrophosphate amidotransferase, PPAT, when comparing colorectal tumors to the tissue of origin, the colon. PPAT mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of PPAT in rectal tumors was correlated with overall survival in patients with rectal cancer. PPAT expression changes may be important for the initiation or progression of human CRC.
Spatial variability and temporal stability of corn response to nitrogen and seed rates in on-farm precision experiments
Authors: Alesso Carlos Agustin , Martin Nicolas
Published: March 2023

Geographically weighted regression (GWR) analysis and on-farm precision experiments (OFPE) allow the quantification of the within-field spatial variability of crop response to controllable inputs. Few studies have quantified the magnitude and consistency of these responses across years, and their relationship with site-specific characteristics. In this study we: (1) assessed the within-field spatial variability of corn response to nitrogen (NR) and seed (SR) rates using OFPE data and GWR models; (2) determined the spatial agreement between NR and SR response classes, and their temporal stability; and (3) modeled the effect of weather and site-specific features on the spatial distribution of the responses. Response maps were estimated by fitting GWR models to yields and as-applied NR and SR from 14 OFPE. Response maps classified into positive and non-positive response classes were spatially joined to weather, soil, and landscape covariates to train a random forest model. Zones with positive responses to NR and SR were detected in all fields. In most cases, these zones were inconsistent across years due to weather. The higher spatial agreement between NR and SR response classes for the same year suggests that factors controlling the crop response to these inputs are similar. In both cases, weather variables were the most important predictors followed by landscape and soil attributes. Whereas weather variables acted at a field level, i.e. field-year, the latter reflected the effect of within-field variability on crop response. To reduce this seasonal uncertainty, future research should consider conducting larger numbers of OFPE across multiple seasons.
Differential expression of SLC17A4 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding solute carrier family 17 member 4, SLC17A4, when comparing colorectal tumors to the tissue of origin, the colon. SLC17A4 mRNA was present at significantly lower quantities in tumors of the colon as compared to normal colorectal tissue. SLC17A4 expression changes may be important for the initiation or progression of human CRC.
Complex rupture evolution of the 2007 Martinique earthquake: a non-double-couple event in the Caribbean Sea
Authors: Ohara Kenta , Yagi Yuji , Okuwaki Ryo
Published: March 2023

A large non-double-couple component of a tectonic earthquake indicates that its rupture likely was complex and likely involved multiple faults. Detailed source models of such earthquakes can add to our understanding of earthquake source complexity. The 2007 Martinique earthquake in the Caribbean Sea is one of the largest recent earthquakes with a known large non-double-couple component. It was an intermediate depth intraslab earthquake within the South America plate where it is subducting beneath the Caribbean plate. We applied potency density tensor inversion (PDTI) to teleseismic P waves generated by the 2007 Martinique earthquake to model its source processes and focal mechanism distribution. We identified two focal mechanisms: a strike-slip mechanism with a north–south T axis, and a down-dip extension (DDE) mechanism with an east–west T axis. Rupture by the DDE mechanism was predominant in the northern part of the source region and strike-slip rupture in the southern part. These two focal mechanisms had approximately parallel P axes and approximately orthogonal T axes. The seismic moments released by both types of rupture were almost equal. These results indicate that the 2007 Martinique earthquake had a large non-double-couple component. We identified five sub-events with two predominant directions of rupture propagation: two strike-slip sub-events propagated to the southeast and three DDE sub-events propagated to the east. Although the directions of propagation were consistent for each focal mechanism, each sub-event appears to have occurred in isolation. For example, the rupture of one DDE sub-event propagated from the edge of the source region back towards the hypocentre. Complex ruptures that include multiple sub-events may be influenced by high pore fluid pressure associated with slab dehydration. Our results show that PDTI can produce stable estimates of complex seismic source processes and provide useful information about the sources of complex intermediate depth intraslab earthquakes for which fault geometry assumptions are difficult.
Mobile Sensing Methods
Authors: Schoedel Ramona , Mehl Matthias R.
Published: March 2023

Mobile and wearable devices are equipped with an array of embedded digital sensors that produce continuous steams of digital trace data. These now effectively ubiquitous digital trace data can empower psychologists to study human behavior “in vivo” and “in situ,” which has been an important goal following the American Psychology Association’s “Decade of Behavior” (2000-2009). As a result, there is currently great excitement among psychological scientists about the potentials that sensor-based mobile technologies offer for studying everyday situations and behavior ecologically and at scale. This novel approach to field research is commonly referred to as mobile sensing, or passive sensing. In this chapter we retrace mobile sensing’s journey in social and personality psychology. We begin with briefly reviewing forces that helped pave the way for mobile sensing’s warm welcome in the field. In the second and third part, we provide an overview of the current use of mobile sensing in social and personality psychology and convey a very basic how-to. Finally, we end the chapter with a discussion of where we think mobile sensing currently stands and identify some possible future directions.
Short- and Long-term Efficacy of Transdiagnostic Cognitive Behavioral Therapies for Emotional Disorders: Systematic Review and Meta-Analysis
Authors: Schaeuffele Carmen , Meine Laura Elisabeth , Schulz Ava , Weber Maxi , Moser Angela , Paersch Christina , Recher Dominique Annina , Boettcher Johanna , Renneberg Babette , Flückiger Christoph , Kleim Birgit
Published: March 2023

Transdiagnostic cognitive-behavioral psychotherapy (TD-CBT) may facilitate treatment of emotional disorders. We investigate short- and long-term efficacy of TD-CBT for emotional disorders in individual, group, and Internet-based settings in randomized controlled trials (PROSPERO CRD42019141512). Two independent reviewers screened results from PubMed, MEDLINE, PsycINFO, Google Scholar, medRxiv, and OSF Preprints published between January 2000 and January 2023, selected studies for inclusion, extracted data and evaluated risk of bias (Cochrane risk-of-bias tool 2.0). Absolute efficacy from pre- to post-treatment and relative efficacy between TD-CBT and control treatments were investigated with random-effects models. Of 56 identified studies, 53 (6610 participants) were included in the meta-analysis. TD-CBT had large effects on depression (d = 1.15, 95%CI = 1.03 - 1.28) and anxiety (d = 1.08, 95%CI = 0.95 - 1.21), from pre- to post treatment. Across treatment formats, TD-CBT was superior to waitlist (depression: g = 1.31, 95%CI = 0.88 - 1.74; anxiety: g = 1.22, 95%CI = 0.82 - 1.63) and treatment-as-usual (depression: g = 0.87, 95%CI = 0.63 - 1.11; anxiety: g = 0.94, 95%CI = 0.57 - 1.30). TD-CBT showed comparable effects to disorder-specific treatments, with indications of TD-CBT’s superiority (depression: g = 0.16, 95%CI = 0.01 - 0.32; anxiety: g = 0.15, 95%CI = 0.04 - 0.26). Large effects were reported for Internet-based TD-CBT for up to 2 years. Studies were heterogeneous in design and methodological quality. This review and meta-analysis strengthens the evidence for TD-CBT as an efficacious treatment for emotional disorders in different settings.
Nutraceutical Potential of Vitexin: A Flavone Glycoside
Authors: Ranjan Rajeev , Kishore Kaushal , TJ Sheikh , Jha Amit Kumar , Ojha Brijesh Kumar , Kumar Suman , Kumar Rinesh
Published: March 2023

Vitexin is an apigenin flavone glycoside and it is extensively present in numerous edible and medicinal plants. It is considered as important as other flavonoids. It possessed a variety of biological properties, including anti-oxidation, anti-inflammation, anticancer, neuron-protective, cardio-protective, hepatopancreatic protective effects. Other reported health relevant effects, includes fat reduction and glucose metabolism. The possible mechanism of protective effect through activation or inhibition of the different signaling pathways like AMPKa, Nrf-2, mTOR, PUMA, MMP, PARP, JNK, p38, Bcl-2/Bax ratio etc. The molecular targets of vitexin are very critical to utilize its potential effect as emerging chemopreventive and chemotherapeutic agent.
The role of Household Welfare on Child Well-being in Vietnam
Authors: Ngo Thi Xuan Phuong , Le Thi Bao Yen , Le Trung Phung , Tran Khanh Chi , Nguyen Thi Lan
Published: March 2023

This research analyzes the relationship between household welfare on child well-being in Vietnam. By applying the OLS regression model on a secondary data set from the Vietnam Sustainable Development Goal Indicators for Children and Women survey by the General Statistics Office (GSO) and the United Nations International Children's Emergency Fund (UNICEF) in the period 2020-2021, research shows that high household welfare has positive effects on all six constitutive dimensions of child well-being. The research results serve as a reference base to provide some recommendations to increase and balance household welfare across regions, thereby improving child well-being in Vietnam.
Fatigue Failure
Authors: Amjadi Mohammad
Published: March 2023

Failure of structural polymeric materials under cyclic application of stress or strain is a subject of industrial importance. The understanding of fatigue mechanisms (damage) and the development of constitutive equations for damage evolution, leading to crack initiation and propagation as a function of loading or displacement history, represent a fundamental problem for scientists and engineers. This article describes the approaches to predict fatigue life and discusses the difference between thermal and mechanical fatigue failure of polymers.
Formation the productivity of castor plant depending on row spacing and standing density
Authors: Mazurenko Bohdan , Honchar Liubov , Harbar Lesia , Yunyk Аnatolii
Published: March 2023

Selection of plant species, their varieties or hybrids and the formation of their productivity is an urgent need today due to the shortage of biofuel production at the world level. The purpose of the research was to reveal the influence of technological measures (row spacing and density of plant standing) on the formation of elements of the crop structure of castor varieties. Research was conducted during 2020-2021in field conditions to study the influence of plant stand density and row width on the elements of the structure of the castor crop of Khortytska 3 and Olesia varieties in the educational and scientific laboratory "Demonstration Field of Agricultural Crops" of NUBiP of Ukraine. Following methods were used: theoretical (statistical processing) and practical (descriptive, comparative). The following indicators were evaluated: weight of 1000 seeds, number of fruits per plant, weight of seeds per plant. Results. Seed yield of castor variety Khortytska 3 was 1.27–1.46 t/ha with a maximum at a stand density of 50,000 plants/ha and a row width of 70 cm. Seed yield of castor cultivar Khortyts’ka 3 was 1.27–1.46 t/ha with a maximum at the option of standing density 50,000 plants/ha and a row space at 70 cm. Seed yield of cultivar Olesya was 1.34–1.42 t/ha with the selection of the two most productive options: first is row space 45 cm and 37.5 thousand plants/ha; alternative is row space 70 cm and standing density of 50 thousand plants/ha. Seed productivity of one plant can increase almost twice when the standing density is reduced from 50 to 25 thousand plants/ha, with the simultaneous formation of larger seeds. Thousand seeds weight of cultivar Khortyts’ka 3 ranged from 268 to 283 g and it was 294–316 g in cultivar Olesya, It was established that the correlation between seed yield and elements of yield structure is negative or absent at all, and positive with stand density. Research results indicate a high compensatory ability of castor cultivar Khortytska 3 and Olesya varieties in the formation of productivity elements under different stand densities and row widths in the conditions of the Right Bank Forest Steppe of Ukraine. This makes it possible to carry out further research on the influence of sowing parameters in a wider range and to use the obtained results for growing castor in atypical soil and climatic conditions
Структурно-функціональний стан серця у хворих із серцевою недостатністю, які перенесли інфаркт міокарда, залежно від проведеної реперфузії
Authors: Savchuk N. V. , Vakaliuk I. P.
Published: March 2023

Оцінка методу реваскуляризації міокарда через 1 міс показала перевагу перкутанного коронарного втручання над консервативною терапією за рахунок зменшення дилатації лівого шлуночка, його розмірів, підвищення здатності міокарда до скорочення. Ризик смерті хворих з хронічною серцевою недостатністю (ХСН) після перенесеного інфаркту міокарда (ІМ) з проведеною реваскуляризацією шляхом стентування інфарктзалежної коронарної артерії BMS нижчий, ніж у хворих без проведення реперфузії. Таким чином, своєчасна реваскуляризація забезпечує зворотне ремоделювання лівого шлуночка, покращання його регіонарної та глобальної функції і зменшення проявів ХСН. Реперфу- зійна терапія покращує перебіг післяінфарктного кардіосклерозу і тому повинна стати пріоритетним напрямом лікування хворих в гострому періоді ІМ.
Вплив s-амлодипіну і небівололу на динаміку показників нейрогуморальної й системної імунозапальної активізації, ендотеліальних і мітогенних факторів росту та індукторів апоптозу у хворих з артеріальною гіпертензією
Authors: Seredyuk V. N.
Published: March 2023

У статті досліджено вплив S-амлодипіну і небівололу на динаміку показників нейрогуморальної й системної імунозапальної активізації, ендотеліальних і мітогенних факторів росту та індукторів апоптозу у хворих з артеріальною гіпертензією (АГ) у поєднанні з хронічними обструктивними захворюваннями легень (ХОЗЛ). Обстежено 95 хворих (64 чоловіки, 31 жінка) на АГ ІІ стадії і І–ІІІ ступеня у поєднанні з ХОЗЛ ІІІ стадії у фазі ремісії, середній вік – (54,7 ± 9,5) року. Встановлено, що додаткове призначення S-амлодипіну чи небівололу до еналаприлу на фоні стандартної терапії приводить до суттєвого зменшення нейрогуморальної та системної імунозапальної активізації, надмірного продукування ендотеліальних і мітогенних факторів росту та індукторів апоптозу у хворих на АГ у поєднанні з ХОЗЛ.
Функція нирок і верхніх сечовивідних шляхів у хворих на рак сечового міхура
Authors: Stakhovsky E. A. , Kononenko O. A. , Voylenko O. A. , Vukalovich P. S. , Vitruk Y. V. , Pikul M. V. , Semko S. L. , Marinichenko M. V.
Published: March 2023

Рак сечового міхура (РCМ) посідає сьоме місце в світі в структурі злоякісних новоутворень у чоловіків. Ми вивчали функціональний стан нирок та уродинаміки у хворих на рак сечового міхура до та після цистектомії. Клінічний аналіз проведено у 155 пацієнтів з місцево-поширеним (Т3в–Т4) та метастатичним (N1–3 або M1) РСМ, яким викона- но обстеження та спеціальне лікування з 2008 по 2016 рр. у науко-дослідному відді- ленні пластичної та реконструктивної онкоурології Національного інституту раку. Віддалені результати вивчено у 128 (82,6 %) хворих. Обструкцію верхніх сечовивідних шляхів (ВСШ) діагностовано у 96 (61,9 %) хворих на РСМ. цистектомію з деривацією сечі виконано у 155 (100 %) хворих: деривацію сечі за Brikcer – у 85 (54,9 %); деривацію сечі за Сооk – у 6 (3,9 %); модифіковану уретерокутанеостомію – у 33 (21,3 %); ілео- неоцистопластику – у 23 (14,8 %); ілеосигморезервуар – у 5 (3,2 %), Mainz pouch II – у 3 (1,9 %) хворих. Проведення цистектомії з деривацією сечі дало можливість змен- шити кількість хворих з ХНН від 72 (46,5 %) до 43 (33,6 %) у віддаленому післяопераційному періоді (Р = 0,06). Порушення уродинаміки та функції нирок при місцево-поширеному і метастатичному РСМ спостерігали у 62 % хворих. цистектомія при місцево-поширеному та метастатичному РСМ дозволяє усунути обструкцію ВСШ, покращити функцію нирок, що створює умови для проведення ад’ювантної поліхіміо- терапії (ПХТ).
Информативность алгоритма FRAX® в оценке риска остеопоротических переломов у женщин украинской популяции
Authors: Povoroznуuk V. V. , Grуgorieva N. V. , Prostenko V. V. , Kanis J. A. , Johansson H. , McCloskey E. V.
Published: March 2023

FRAX® – метод (алгоритм) оценки 10-летнего риска перелома бедренной кости и других основных остеопоротических переломов у лиц в возрасте 40 лет и старше, разра ботанный с использованием показателей возраста, индекса массы тела, минеральной плотности костной ткани и различных клинических факторов риска переломов. В настоящее время FRAX® включён в большинство европейских и американских рекомендаций по профилактике и лечению остеопороза. Статья посвящена результатам разработки и адаптации украинской модели FRAX®, которая в 2016 г. появилась на официальном интернет-ресурсе FRAX® (http://www.sheffield.ac.uk/FRAX/?lang=uk). Её создание основано на результатах эпидемиологических исследований, проведённых в последние годы Украинской ассоциацией остеопороза, Украинским НМц проблем остео- пороза при поддержке Украинской ассоциации травматологов-ортопедов. Украинская модель FRAX® является первой отечественной моделью прогнозирования риска основных остеопоротических переломов и перелома бедренной кости, которая создана по оригинальной методике FRAX®. Данная модель уникальна, поскольку основана на результатах эпидемиологических исследований в Украине, отражает национальные тенденции в распределении остеопоротических переломов, является информативной и обосновывает необходимость широкого её внедрения в клиническую практику.
Ефективність комбінованої терапії у хворих із загостренням хронічного обструктивного захворювання легень
Authors: Dobrianskyi D. V. , Dudka P. F. , Ilnytskyi R. I. , Tarchenko I. P. , Reznikova N. M.
Published: March 2023

Проведено оцінку ефективності застосування фенспіриду та антигомотоксичних препаратів у комбінації із стандартною терапією у хворих на хронічне обструктивне захворювання легень (ХОЗЛ) І–ІІ стадії в період загострення з урахуванням стану реології крові та імунної системи. Порушення реологічної характеристики крові відмічено у 2/3 хворих на ХОЗЛ І–ІІ стадії у фазі загострення. У хворих на ХОЗЛ виявлено три типи реакцій системного імунітету: гіперергічний (5 показників та більше збільшені на ≥ 20 %), гіпоергічний (5 показників та більше зменшені на ≥ 20 %), деякі імунні порушення (від 1 до 4 показників зменшені на ≥ 20 %), що дозволяє диференційовано проводити терапію фенспіридом і антигомотоксичними препаратами.
Ефективність та безпечність інтратекального введення морфіну гідрохлориду для лікування хронічного больового синдрому у хворих на онкологічні захворювання в термінальній стадії
Authors: Zhuk V. I. , Novosad I. I.
Published: March 2023

Біль – одна з найпоширеніших причин звернення пацієнтів до лікаря. Якщо біль тривалий, він може не лише призвести до фізичної неповноцінності, а й спричинити емоційний, психологічний тиск на пацієнтів та їхнє оточення. Хронічний біль надзвичайно поширений. Інтратекальне введення опіоїдів широко використовують при вираженому больовому синдромі у хворих на некурабельний рак звичайними методами. Тому інтратекальне введення морфіну гідрохлориду може значно полегшити біль.
Особливості формування прикусу в осіб віком від 6 до 12 років залежно від характеру харчування
Authors: Fera O. V. , Kostenko Ye. Ya. , Fera M. O. , Melnik V. S. , Kryvanych V. N. , Melnik S. V.
Published: March 2023

У статті проаналізовано та вивчено вплив характеру харчування на формування прикусу у дітей віком 6–12 років. Проведено стоматологічний огляд та анкетування серед даної групи населення в Закарпатській області і отримано такі результати: всього анкет – 337, ортогнатичний прикус – у 140 (41,54 %), мезіальний прикус – у 77 (22,85 %), перехресний прикус – у 57 (16,91 %), відкритий прикус – у 24 (7,12 %), патологічна прогнатія – у 22 (6,53 %), фізіологічна прогнатія – у 17 (5,05 %). Вико- нано гігієнічно-статистичний аналіз впливу характеру харчування на формування шести досліджуваних видів прикусу. Виділено фактори, що впливають на формування патології прикусу та визначено коефіцієнт кореляції за шкалою Чеддока. Наведено дисперсний аналіз вищезазначених факторів, а також коефіцієнт репрезентативності.
Оценка риска функциональных нарушений у работников, занятых на подземных горных работах
Authors: Vlasova E. M. , Alekseev V. B. , Shljapnikov D. M. , Shevchuk V. V.
Published: March 2023

Снижение функциональных возможностей организма наступает до первых признаков болезни и является прогностически неблагоприятным признаком. Группу наблюдения с оценкой состояния здоровья составили машинисты горных выемочных машин (ГВМ), занятых на выполнении подземных работ по добыче калийных солей, группу сравнения – работники, выполняющие работы на поверхности. Для оценки уровня адаптации и адаптационного потенциала у работников обеих групп проведено комплексное обследование показателей здоровья. Установлено, что выполнение подземных горных работ способствует перенапряжению и истощению адаптивных резервов организма, что увеличивает риск формирования заболеваний нервной и сердечно-сосудистой систем. Адаптационные возможности работника должны быть одним из основных критериев при экспертизе профессиональной пригодности у работников, занятых на подземных работах, а также при разработке профилактических программ, направленных на ссохранение здоровья работника и профессиональное долголетие.