bluuebunny/crossref_metadata_2025 huggingface dataset:
Construction of a Transgenic Beauveria bassiana (Hypocreales: Cordycipitaceae) Strain Expressing the SPHvt/GNA Fusion Protein and Determination of its Toxicity to Anopheles stephensi (Diptera: Culicidae) Larvae1
Authors: Li Hongxing , Zhai Suzhen
Published: October 2024

Mosquitoes transmit numerous diseases, including malaria and dengue fever, making mosquito control crucial for managing the spread of these and other illnesses. Beauveria bassiana (Balsamo-Crivelli) Vuillemin (Hypocreales: Cordycipitaceae) holds promise for the biological control of mosquito vectors but faces challenges such as low pathogenicity, lengthy infection periods, reduced longevity, and a dependence on specific environmental conditions (e.g., temperature and humidity) for spore germination, thus impacting its efficacy. To address this, a strain of B. bassiana was engineered to carry the SPHvt/GNA fusion pathogenicity protein-encoding gene. A plasmid containing the gpdA promoter, GFP gene, and SPHvt/GNA gene was constructed using molecular cloning techniques, including digestion and ligation, based on the base plasmids pBarGPE1 and pBarGFP. The engineered vector plasmid pBarGFPSPHvt/GNA was integrated into the genome of B. bassiana Bb252 through Agrobacterium tumefaciens-mediated fungal genetic transformation, resulting in B. bassiana strains with the SPHvt/GNA fusion pathogenicity protein-encoding gene. These transgenic strains were identified through fluorescence screening and confirmed at the genomic, transcriptional, and protein levels. A spore suspension of Bb252::BarGFPSPHvt/GNA was applied to Anopheles stephensi Liston (Diptera: Culicidae) larvae. The effect of pathogenicity on larval survival was assessed, and the infection process was monitored. The results indicated that the construction of a transgenic B. bassiana strain for potential management of mosquito larvae.
Zakat Calculation Model as a Reduction Factor for Income Tax Based on Law Number 11 of 2006 concerning the Government of Aceh
Authors: Nazaruddin  , Nasir Muhammad , Fauzan Ahmad
Published: October 2024

The purpose of this study is to examine the implementation of the provisions of Law Number 11 of 2006, especially Article 192 which regulates Zakat as a deduction from income tax. In this study, the researcher examines the extent to which this rule is applied in practice and attempts to evaluate the most effective zakat calculation model as a deduction from income tax. This study uses qualitative methods through interviews, observations, and documentation regarding Zakat as a deduction from tax. The research findings indicate that the implementation of the provision of zakat as a deduction from tax as regulated in Article 192 of Law Number 11 of 2006 has not been optimal in Aceh, especially in Lhokseumawe City. Although this law provides a strong legal basis, the practice in this field still refers to Law Number 23 of 2011 concerning Zakat Management. The implementation of Law Number 23 of 2011 in Lhokseumawe only focuses on the administration and distribution of zakat without providing clear guidelines in integrating zakat into the taxation system, thus inhibiting the use of zakat as a tax reduction tool.
Zrównoważone zachowania konsumentów – wybrane zagadnienia
Authors: Sielicka-Różyńska Maria
Published: October 2024

Sustainable consumer behavior – selected aspects. The purpose of the chapter is to present consumers’ activities and behaviors that should be implemented to achieve sustainable and responsible consumption. The chapter is prepared basing on current literature, reports and companies organisational documents. Sustainable consumption assumes optimal and conscious use of available resources to achieve development, while minimising the harmful impact on the environment and ensuring satisfaction for both the current and future generations. The key element in ensuring sustainable consumption is conscious and responsible consumer, as a representative of the household, that should be aware and comply with Zero Waste rules, that are in line with Sustainable Development Goals. Initiatives such as foodsharing, community kitchens, using mobile applications to reduce the surplus food, freeganism or following plant-based diets might be crucial in achieving sustainable food consumption and, among others, reduction of food waste. There is a big need to increase the awareness of consumers in terms of sustainable behaviors and their access to information through, e.g., social campaigns.
Wykorzystanie sztucznej inteligencji na rzecz rozwoju miast i regionów
Authors: Czyżewska-Misztal Dorota
Published: October 2024

The use of artificial intelligence for the development of cities and regions. The use of AI is becoming omnipresent, also for territorial development. In the cities and regions one can observe diverse use cases of its implementation ranging from waste management, education support, traffic management, to climate change challenges and many others. The aim of this study is to discuss the importance of solutions based on artificial intelligence for the development of cities and regions by outlining its importance using the perspective of current literature studies and discussing examples of specific solutions based on AI used in selected cities and regions in Europe. The study uses literature review and case study as main research methods. The study shows the growing importance of AI technologies for urban and regional purposes from the theoretical and empirical perspective. One cannot therefore forget to take into account potential threats that appear especially with the growing interest devoted to generative AI.
Transformacja energetyczna w Unii Europejskiej w latach 1990-2021
Authors: Drelich-Skulska Bogusława , Brusiło Paweł
Published: October 2024

The energy transition in the European Union in the years 1990–2021. Energy transition is one of the global challenges that is part of a wider process of adapting the European Union’s development strategy to climate change and its energy policy. The aim of this chapter is to present the EU’s energy transition from 1990 to 2021, in relation to the EU’s energy policy objectives. The authors have reviewed the literature on the energy transition in the EU, selected macroeconomic indicators characterising the structural transformation in the energy sector of EU members and the legal acts that shape this process. The chapter presents the results of studies that show a significant increase in the importance of renewable energy sources (RES) in the structure of primary energy consumption and changes in the structure of final energy consumption in individual sectors. During the period under review, the EU adopted ambitious targets and instruments to reduce greenhouse gas emissions, including carbon dioxide (CO 2) emissions, from the energy sector and to increase energy efficiency in general, which translated into a significant change within the related indicators. On the basis of the research carried out, it can be concluded that the energy transition process in the EU has led to significant structural changes in this area, characterised by significant dynamism and impact of the energy policies implemented by the European Union.
The Problem of Education in Russia in the Period of Construction of Saint Petersburg (the First Quarter of the 18th Century)
Authors:   Postgraduate Student of the Department of History of State and Law of the Kutafin Moscow State Law University (MSAL), Zaytseva Yulia V.
Published: October 2024

The article is devoted to the problem of education during the reign of Peter the Great on the example of construction of Saint Petersburg. The author reviews some problems of organization and performance of construction works that revealed the need for reformation and creation of a system of education in Russia.
On Problems of Digitalization of the Legal Profession
Authors:   ssociate Professor of the Department of Constitutional, Administrative, and Civil Procedure of the Ulyanovsk State University, Artemova Svetlana T. , Bagaley Ekaterina I. ,   Legal Counsel at OAK-Resource, LLC
Published: October 2024

The article analyzes the peculiarities of the formation and development of information digital society at the present stage and the associated emergence of the problem of forming a new level of specialists in the legal sphere. First of all, modern lawyers, in the conditions of rapid digitalization of all spheres of life and constant technological improvement, should be fluent in ITtechnologies and be able to apply them in practice. Besides, a modern lawyer should have an idea of new digital software products that, on the one hand, will significantly simplify the work, accelerate the process of preparing standardized documentation, and at the same time improve its quality by introducing artificial intelligence into new programs.
On Implementation of the Idea of Forced Licensing of Items of Copyright and Related Rights in Russia
Authors:   Senior Research Scientist of the Department of Procedure Law of the Institute of State and Law of the Russian Academy of Sciences, Borisova Lilia V.
Published: October 2024

The article draws attention to the controversial assessment by experts in the field of intellectual property of the implementation in Russia of the idea of compulsory licensing of objects of copyright and related rights. It is shown that compulsory licensing is a measure of last resort, the use of which is permissible only as an exception. Compulsory licensing of objects of copyright and related rights is supported from the point of view of economic efficiency in relation to works of unknown copyright holders, subject to the rights of authors to fair remuneration.
Peculiarities of Legal Regulation of Procurements Conducted by Healthcare Institutions
Authors:   Specialist of the Territorial Fund for Compulsory Medical Insurance of the Republic of Crimea, Kucher Elena S.
Published: October 2024

The article, on the basis of federal legislation explaining the letters of departments and legal positions of the courts, reflects the peculiarities of procurement by health care institutions, expressed in the methods of determining the supplier, a detailed description of the object of purchase, the specifics of calculating the initial maximum price of the contract, including the author’s definition of procurement of health care institutions.
Appointment of Tenders Used in the Disposal of Public Property
Authors:   Head of the Department of Legal, Documentation and Personnel Support of the Federal State University of Education, Postgraduate Student of the Institute of Legislation and Comparative Law under the Government of the Russian Federation, Korolev Evgeny V.
Published: October 2024

In the process of public property rights transfers, bidding procedures are often used, and the goals and functions of this legal institution are the subject of debate in the legal literature. The use of a functional approach allows us to support the position of the Constitutional Court of the Russian Federation, according to which bidding procedures are legal procedures. Economic analysis of bidding procedures, being used in transfers of public property rights allows us to highlight their main goal, which is making an economically sound decision on the choice of optimal terms of the contract and the counterparty ready to offer them, in the conditions of information asymmetry, as well as the presence of additional tasks arising from the need to ensure implementation principles of management of public property.
On Improving Legal Support of the Quality of the Urban Environment in the Russian Federation
Authors:   Junior Research Scientist of the Department of Financial Law, Constitutional, Civil and Administrative Proceedings, Lecturer of the Department of Industrial and Civil Construction of the Southwest State University, Chaykovskaya Lilia V.
Published: October 2024

In the Russian Federation, in order to determine the urban environment quality index as a target indicator of the federal project “Formation of a comfortable urban environment”, a methodology for the formation of an urban environment quality index has been introduced. This methodology does not contain the definition of “comfortable urban environment”, however, it has 36 indicators for its assessment. This article distributes indicators according to the accepted elements of a comfortable urban environment, and concludes that it is advisable to improve the methodology under consideration by supplementing indicators characterizing individual elements of a comfortable urban environment.
The Importance of the Scientific Heritage of N.G. Salischeva for the Development of Principles of the Administrative Procedure
Authors:   PhD (Law), Associate Professor, Associate Professor of the Department of Administrative Law and Procedure Named after N.G. Salischeva of the Russian State University of Justice, Zyuzin Vitaliy A.
Published: October 2024

The article is devoted to the study of N.G. Salishcheva’s positions regarding the definition of the principles of the administrative process. The influence of the doctrine of public administration on the principles of the process in Soviet times is analyzed, the correlation of administrative procedural principles and well-known principles of civil and criminal processes is investigated. Special attention is paid to the principle of competition in the administrative process. The article rethinks some of the principles defined by the classic of the domestic administrative process in terms of their transformation under the influence of modern legislation and judicial practice.
Administrative Dispute in the Heritage of Nadezhda G. Salischeva and the Contemporary Russian Legal System
Authors:   PhD (Law), Associate Professor, Associate Professor of the Department of Administrative Law and Procedure Named after N.G. Salischeva of the Russian State University of Justice, Poryvaev Sergey A.
Published: October 2024

The article examines the development of N.G. Salishcheva’s views on the institution of administrative dispute, its importance for the protection of citizens’ rights. The perception of her positions and ideas in Russian legislation is indicated. The paper analyzes the existing system of administrative disputes in Russian law, the features and interrelation of judicial and extrajudicial disputes, as well as the shortcomings of existing legal regulation and the possibilities of overcoming them.
Scientific Justification of the Rule-Making Initiative of Federal Executive Authorities
Authors:   PhD (Law), Department Head of the National Research Institute of the Ministry of Interior of the Russian Federation, Anisiforova Maryam V. , Tsokolova Olga I. ,   Honored Lawyer of the Russian Federation, LL.D., Professor, First Deputy Head of the National Research Institute of the Ministry of Interior of the Russian Federation
Published: October 2024

Ignoring the significance of the role of science and the scientific substantiation of rule-making initiatives of federal executive authorities is fraught with defects and poor quality of the created legal norms, which ultimately affects the state of legal regulation of specific life situations. Drawing attention to the importance of intensifying the scientific component in rule-making, the article attempts to identify some of the weaknesses of this process, on the one hand, and the advantages, on the other. As a result, based on the positive example of the implementation of the rule-making function by the internal affairs bodies of the Russian Federation, primarily the participation in it of a scientific organization and scientific personnel, the prospects for taking into account and disseminating the relevant experience to executive and administrative bodies are substantiated.
On Some Problems of Administrative Liability of Legal Entities
Authors:   PhD (Law), Associate Professor of the Department of Administrative Law and Procedure Named after N.G. Salischeva of the Russian State University of Justice, Trofimova Inessa A.
Published: October 2024

The article examines the problems of administrative responsibility of legal entities, highlights some principles of administrative responsibility. Special attention is paid to the analysis of administrative penalties applied to legal entities. The author examines the main aspects of the administrative responsibility of legal entities, its role and importance in society, as well as identifying the features of the application of this instrument of legal regulation, taking into account the opinion of Professor N.G. Salishcheva.
Control (Supervisory) Activities under the Laws of the Russian Federation: Types, Content and Application Purposes
Authors:   PhD (Law), Associate Professor of the Department of Legal Disciplines of the Astrakhan Branch of the Russian Presidential Academy of National Economy and Public Administration (RANEPA), Solovyev Aleksandr A.
Published: October 2024

The article discusses the main types of control (supervisory) measures carried out in the Russian Federation in accordance with current legislation. Their content, legal bases, goals and objectives are revealed. The author analyzes the features and differences of various types of control and supervision. Based on the analysis of the regulatory framework and application practice, the essence and importance of control (supervisory) measures to ensure the legality, efficiency and effectiveness of the activities of state bodies, local governments, legal entities and individual entrepreneurs are considered.
Psychological Support of Judges in Foreign Countries
Authors:   Associate Professor of the Department of Arrangement of Judicial and Law Enforcement Activities of the Russian State University of Justice, Kuznetsova Marina A.
Published: October 2024

The article reviews issues related to the study of psychological support of court staff in foreign countries.
Prosecutor and Attorney in Court: History and the Modern Times
Authors:   Head of the Department of Prosecutor's Supervision over Law Enforcement in Criminal Intelligence and Surveillance Operations and Prosecutor's Involvement in Criminal Proceedings of the Kazan Law Institute (Branch) of the University of Prosecutor's Office of the Russian Federation, Bagautdinov Fler N.
Published: October 2024

The article studies the role of a prosecutor and an attorney in a court hearing that reviews criminal cases from the historical standpoint.
An Analysis of Contemporary Research of Psychological Security of an Individual in the Educational Environment
Authors:   Junior Scientific Assistant of the Department of Legal Psychology of the Saint Petersburg University of the Ministry of the Interior of the Russian Federation, Kazakov Vladimir S.
Published: October 2024

The article presents an analytical review of studies devoted to the concept of psychological security and the concept of psychological security of a student's personality, through the generalization of scientific works of domestic and foreign researchers. Currently, during the existence of multiple hybrid threats, the need for personal security is increasing many times. This direction is becoming extremely relevant in relation to students, especially to students of educational organizations of law enforcement systems, including the system of the Ministry of Internal Affairs of Russia. In particular, the peculiarities of the influence of psychological parameters of the educational environment, especially the educational environment of organizations with a specific law enforcement orientation on the mental state of students, precisely at the present information-rich stage of the development of modern society, have not been fully investigated. In addition, the features of modern mechanisms of psychological security of a student's personality, including a student of an educational organization of the Ministry of Internal Affairs of Russia.
Local inclusive distance antimagic coloring of graphs
Authors: Hadiputra Fawwaz Fakhrurrozi , Farhan Mohammad , Mukayis Mukayis , Saputro Suhadi Wido , Maryati Tita Khalis
Published: October 2024

For a simple graph G, a bijection f : V(G) → [1,|V (G)|] is called as a local inclusive distance antimagic (LIDA) labeling of G if w(u) ≠ w(v) for every two adjacent vertices u,v ∈ V(G) with w(u) = ∑x∈N [u] f(x). A graph G is said to be local inclusive distance antimagic (LIDA) graph if it admits a LIDA labeling. The function w induced by f also can be seen as a proper vertex coloring of G. The local inclusive distance antimagic (LIDA) chromatic number of G, denoted by χlida(G), is the minimum number of colors taken over all proper vertex colorings induced by LIDA labelings of G. In this paper, we study a LIDA labeling of simple graph. We provide some basic properties of LIDA labeling for any simple graphs. The LIDA chromatic number of certain multipartite graphs, double stars, subdivision of graphs and join product of graphs with K1 are also investigated. We present an upper bound for graphs obtained from subdivision of super edge-magic total graphs. Furthermore, we present some new open problems.
Empirikus bizonyítékok a vállalatok társadalmi felelősségvállalásának pozitív befektetői és fogyasztói megítélésére
Authors: Takács András
Published: October 2024

A társadalmi felelősségvállalás szükségességét, jelentőségét már sok évtizede felismerték a felelős vállalatvezetők, aminek hatására ez a szemlélet elkezdett beáramlani a vállalati politikákba és gyakorlatokba. Napjainkban a társadalmi felelősségvállalást az üzleti világ szereplői a széles körben ismert ESG-szempontrendszer második pilléreként azonosítják, amely a vállalatok éves rendszerességgel elkészülő beszámolójának kötelező részét képezi az uniós szabályozás értelmében. A vonatkozó EU-direktíva kiadása óta számos kutatás tűzte ki feladatként annak igazolását, hogy a vállalatok felelős magatartása nemcsak egy magasabb cél teljesítését szolgáló nemes gesztus a társadalom felé, hanem pénzügyi értelemben is megtérülő, pozitív hozamú befektetés. A témában született nemzetközi publikációk meggyőzően igazolták, hogy a vállalatok ezen erőfeszítéseit a tőzsdei befektetők értékelik, ami a részvényárfolyam és a cég tőzsdei értékének emelkedésében válik láthatóvá. Ugyanakkor a kutatások sokkal kevesebb figyelmet fordítottak a társadalmi felelősségvállalás fogyasztói megítélésre gyakorolt hatásával. Tanulmányom erre a kutatási résre irányul, a fogyasztói megítélés mérőszámaként a márkaértéket használom fel. Vizsgálatomban 26 nemzetközi nagyvállalat 2012 és 2021 közötti adatai alapján statisztikai eszközökkel igazolom, hogy a társadalmi felelősségvállalás nemcsak a befektetői, hanem a fogyasztói megítéléssel is szignifikáns pozitív együttmozgást mutat.
Разработка методики создания синтетических томограмм пористых сред
Authors: Lavrukhin Efim Valer'evich , Murygin Dmitrii Alekseevich , Toropov Konstantin Vital'evich , Khlyupin Aleksey , Gerke Kirill Mironovich
Published: October 2024

Рентгеновская компьютерная томография (КТ) является одним из ключевых методов исследования внутреннего строения пористых образцов, например, пород-коллекторов нефти и газа. Для дальнейшего моделирования физических свойств пористых сред
КТ-изображения необходимо предварительно сегментировать - разделить на твердую и пустотную фазы. Однако правильность сегментации невозможно проверить ввиду отсутствия данных о точном внутреннем строении материала.
В настоящей работе описана разработанная методика и ПО на еe основе для создания синтетических томограмм пористых сред с целью решить проблему отсутствия валидационных или тренировочных изображений сегментации. Созданный фреймворк основан на прямом и обратном преобразовании Радона. Для проверки предложенного подхода мы сравнили скорость и качество работы ключевых алгоритмов с существующими аналогами. На основе прокси-образцов, полученных сегментацией КТ-изображений, созданы синтетические изображения пористых сред из пяти фаз: пор (воздух с незначительным поглощением излучения), каолинита (Al$_2$Si$_2$O$_5$OH$_4$), диоксида кремния (SiO$_2$), карбоната кальция (CaCO$_3$) и дисульфида железа (FeS$_2$).
Наблюдается хорошее соответствие получаемых синтетических данных в сравнении с оригинальными КТ-изображениями. Разработанная методика позволяет решить проблему создания размеченных данных для использования машинного обучения в задачах сегментации КТ-изображений, а также для тестирования любых других методик для сегментации КТ-изображений.
Об эффективности применения визуальных трансформеров в обнаружении аномалий гистопатологических изображений
Authors: Shchetinin Eugene Yu
Published: October 2024

Рак молочной железы является одним из наиболее распространенных и опасных видов онкологии у женщин. Современные подходы к его раннему обнаружению и лечению все чаще используют методы искусственного интеллекта и глубокого обучения. В работе исследованы гистопатологические изображения молочной железы с использованием нейронных сетей-трансформеров и глубоких нейронных сетей. В качестве моделей трансформеров использованы модели Vision Transformer (ViT), Data Efficient Image Transformer (DeiT). В качестве моделей глубоких сверточных нейронных сетей выбраны модели ResNet50, VGG16, DenseNet201, EfficientNet-B7, Xception. Все модели были предварительно обучены на наборе изображений ImageNet1к, а затем дообучены на наборе из 4356 гистопатологических изображений. В результате компьютерных экспериментов установлено, что модель EfficientNet-B7 превзошла другие модели, достигнув показателя точности 95.84%. Для повышения производительности моделей классификации гистопатологических изображений в работе применен метод дистилляции знаний, что позволило получить новую модель глубокой нейронной сети-трансформера DeiT_B_dist для высокоточной классификации гистопатологических изображений и обнаружения рака молочной железы. Показатели ее точности составили 98.14% и превзошли остальные модели, а также сопоставимы с результатами работ других исследователей.
Валидационный расчет несжимаемого течения в системе пористое тело--свободный поток
Authors: Churbanov Aleksandr Georgievich
Published: October 2024

Работа посвящена обоснованию применимости модели для сопряженного расчета течений в системе пористое тело--свободный поток. Рассмотренная модель основана на обобщенных уравнениях Навье--Стокса для несжимаемой жидкости, полученных осреднением по представительному элементарному объему пористой среды и записанных для всей расчетной области, включающей в себя как пористое тело, так и чистую жидкость. Численная реализация модели выполнена с использованием открытой вычислительной платформы FEniCS. Для тестирования модели использовались данные экспериментов, в которых измерялись профили скорости потока жидкости в канале прямоугольного сечения, частично заполненном пористым телом. Модельное пористое тело представляло собой квадратный массив параллельных круглых стержней, расположенных вертикально на участке дна канала. Валидационные расчеты течения, соответствующего режиму фильтрации Дарси, показали хорошее совпадение численных результатов со значениями локальных измерений в широком диапазоне величины пористости.
La cultura del acordeón en los modelos Compadre y Corona de Hohner
Authors: García Soto Lizardo
Published: October 2024

Cuando se aborda el tema de la música, es natural asociarlo con una persona que canta o toca algún instrumento. Aunque no es un requisito estricto para la creación musical, solemos encontrar difícil concebir su ejecución sin la presencia de uno de estos elementos. Entender este fenómeno no resulta tan complejo si consideramos la importancia que tiene cualquier instrumento musical en este arte, sobre todo si lo vemos como una parte intrínseca de la cultura.
Ümmet-i/Millet-i Merhûme Terkibini Kullanış Biçimleri Çerçevesinde Mehmet Akif’in Müslüman Toplumlara Yönelttiği Eleştiriler
Authors: Karaçavuş Ahmet
Published: October 2024

Mehmet Akif, her ne kadar şair olarak tanınsa da döneminin sosyal, siyasi, kültürel ve ekonomik sorunlarını inceleyen, Türkçenin yanında iyi derecede Arapça, Farsça ve Fransızca bilen çok yönlü bir düşünürdü. Onun her türlü yönelimini belirleyen ana olgu, içinde yaşadığı çağın kendi ülkesine ve tüm dünya Müslümanlarına getirdiği bunalımdı. Bunalım, bir yandan Müslüman toplumların küresel ölçekte çökerek Avrupa devletlerinin egemenliği altına girmesi, diğer yandan Osmanlı Devleti’nin de aynı akıbete doğru hızla gidiyor olması şeklinde kendini dışsal sebeplere bağlı bir olguymuş gibi gösteriyordu. Şüphesiz bu Avrupa’nın diğer toplum, kültür ve medeniyetlere karşı özellikle bütün XIX. yüzyıl boyunca kazandığı zaferlerin son halkası olacaktı. Hemen her Osmanlı aydın ve siyasetçisi gibi o da özelde Osmanlı, genelde dünya Müslümanlarının içinde bulundukları çöküş ve kaosu önlemenin bir çaresini aramaktaydı. Ancak Akif, sorunun dışsal etki ve görünümlerinden ziyade içsel olana, Müslüman toplumların neyi yapıp neyi yapmayarak çökme hâline geldiklerine odaklanmıştı. Bu noktada onun, bütün Müslümanların içinde bulundukları durumu “ümmet-i/millet-i merhûme” terkibiyle tanımladığı görülmektedir. İlginç olduğu kadar tanımlayıcı olan bu kesin yargı ifadesinin, Müslüman toplumların XX. yüzyılın başında yaşadığı çöküşü, en marjinal düzeyde tespit ve ifade ettiği açıktır. Daha ötesi terim, bizce onun Müslüman toplumlarla ilgili düşüncelerini ifade etmekte kullandığı en önemli kavramlardan biridir.
Canada’s Recreational Cannabis Legalization and Medical Cannabis Patient Activity, 2017–2022
Authors: Armstrong Michael J.
Published: October 2024

Objectives. To estimate changes in medical cannabis patient activity after Canada’s recreational cannabis legalization.

Methods. I used linear regressions of interrupted times series models to analyze medical cannabis patient registrations per 10 000 residents, purchases per 100 registrations, and packages per purchase in Canada’s 10 provinces between April 2017 and December 2022. I tested relationships between the recreational law’s passage in June 2018, recreational sales starting in October 2018, and the arrival of edibles and vapes in December 2019.

Results. Medical patient registrations initially increased; they slowed after the law passed and started decreasing after edibles became available. Medical purchasing frequencies initially decreased; they decreased further in proportion to recreational sales but stabilized after edibles became available. Medical purchase sizes were initially stable; they began increasing after edibles became available.

Conclusions. Canada saw substantial decreases in medical cannabis patient registrations, but the remaining patients stabilized their purchasing frequencies and increased their purchase sizes.

Public Health Implications. Other countries might see significant changes in patient usage of their medical cannabis systems after nationwide recreational cannabis legalization. ( Am J Public Health. 2024;114(S8):S673–S680. https://doi.org/10.2105/AJPH.2024.307721 )
Countermarketing Versus Health Education Messages About Sugar-Sweetened Beverages: An Online Randomized Controlled Trial of US Adults
Authors: Grummon Anna H. , Zeitlin Amanda B. , Lee Cristina J. Y. , Hall Marissa G. , Collis Caroline , Cleveland Lauren P. , Petimar Joshua
Published: October 2024

Objectives. To test whether countermarketing messages for sugary drinks lead to lower intentions to consume sugary drinks and less perceived weight stigma than health education messages.

Methods. In August 2023, we conducted an online randomized controlled trial with US adults (n = 2169). We assessed the effect of countermarketing messages, health education messages, and neutral control messages on intentions to consume sugary drinks and perceived weight stigma.

Results. Both countermarketing messages (Cohen d = −0.20) and health education messages ( d = −0.35) led to lower intentions to consume sugary drinks than control messages ( Ps < .001). However, both types of messages elicited more perceived weight stigma than control messages ( ds = 0.87 and 1.29, respectively; Ps < .001). Countermarketing messages were less effective than health education messages at lowering intentions to consume sugary drinks ( d for countermarketing vs health education = 0.14) but also elicited less perceived weight stigma than health education messages ( d = −0.39; Ps < .01).

Conclusions. Countermarketing messages show promise for reducing sugary drink consumption while eliciting less weight stigma than health education messages, though they may need to be refined further to minimize weight stigma and maximize effectiveness.

Clinical Trial Number. ClinicalTrials.gov NCT05953194. ( Am J Public Health. 2024;114(12):1354–1364. https://doi.org/10.2105/AJPH.2024.307853 )
Metabolic Functions of the Infrapatellar Fat Pad: Implications for Knee Health and Pathology
Authors: Chou Lee S. , Zhang James , Jildeh Toufic R.
Published: October 2024

» Despite being historically viewed as a vestigial structure, the infrapatellar fat pad (IPFP) is now recognized as a metabolically active structure, influencing knee health through cytokine production and metabolic pathways.

» With distinct anatomical regions, the IPFP contains diverse cell types including adipocytes, fibroblasts, and immune cells, influencing its functional roles, pathology, and contributions to knee disorders.

» The IPFP acts as an endocrine organ by releasing adipokines such as adiponectin, leptin, and tumor necrosis factor α, regulating energy balance, immune responses, and tissue remodelling, with implications for knee joint health.

» The IPFP's metabolic interactions with neighboring tissues influence joint health, clinical conditions such as knee pain, osteoarthritis, postoperative complications, and ganglion cysts, highlighting its therapeutic potential and clinical relevance.

» Understanding the multifaceted metabolic role of the IPFP opens avenues for collaborative approaches that integrate orthopaedics, endocrinology, and immunology to develop innovative therapeutic strategies targeting the intricate connections between adipokines, joint health, and immune responses.
WITHDRAWN: Effective symbiosis and activation of protective antioxidant systems for increasing soybean tolerance to drought
Authors: Nyzhnyk Tetiana , Kiedrzyński Marcin , Kiedrzyńska Edyta , Kots Sergii , Zalewski Maciej
Published: October 2024

The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Micro-fungi on medicinal plants in southern China and northern Thailand
Authors: Sun Ya-Ru , Hyde Kevin D. , Liu Ning-Guo , Jayawardena Ruvishika S. , Wijayawardene Nalin N. , Ma Jian , Zhang Qian , Alotibi Fatimah , wang yong
Published: October 2024

This study documents the morphology and phylogeny of micro-fungi collected from various medicinal plants in southern China and northern Thailand. Based on morphological characteristics and phylogenetic analyses, 100 species are identified and distributed in three classes (Dothideomycetes, Leotiomycetes and Sordariomycetes), 16 orders, 37 families and 67 genera. We introduce one new order, Oncopodiellales, three new families, Catenuliconidiaceae, Diplocladiellaceae and Oncopodiellaceae, one new genus, Biascospora, and 54 new species: Achroiostachys browniana, A. catenate, A. fusiformispora, Acrocalymma xishuiense, Amphisphaeria hibiscicola, Apiculospora thailandensis, Arecophila maolanensis, A. yunanensis, Barriopsis caryotae, Biascospora chishuiensis, Conioscypha synnemata, Diaporthe ervatamiae, D. kunmingensis, D. tu-chungcola, D. xishuiensis, D. hannanensis, Distoseptispora gelatinosa, D. greeniana, Gregatothecium diflugoscola, Helicosporium multiseptatum, Helminthosporium thailandicum, Kalmusia tetrastigmae, Keissleriella yunnana, Lasiodiplodia houttuyniae, L. poacearum, Leptospora houttuyniae, Lophiotrema asexualis, L. guizhouense, Melanopsamma tongrenensis, Memnoniella chiangmaiensis, Murichromolaenicola dendrobii, Neoheleiosa brownii, Neohelicascus guizhouensis, Neohelicomyces sexualis, Neohendersonia tongrenensis, Neomassaria fibraureae, Neoscytalidium dendrobii, Parabahusutrabeeja hyalina, Paramyrothecium xishuiense, Phaeosphaeria boehmeriae, P. guiyangensis, Phaeosphaeriopsis spineleae, Porodiplodia guizhouensis, Psiloglonium bambusicola, P. brownii, P. guizhouense, Roussoella panzhouensis, R. wudangensis, Seriascoma guizhouense, Sphaeropsis guiyangensis, Striaticonidium olivaceobrunnea, Tamhinispora obpyriformis, V. chiangraiensis and Virgatospora thailandica, with illustrations, discussions of their taxonomic placement, and comparisons with morphologically similar taxa. Ten new combinations are introduced: Conioscypha chiangmaiense (≡ Vanakripa chiangmaiense), C. minutiellipsoidea (≡ Vanakripa minutiellipsoidea), Conioscypha obovoidea (≡ Vanakripa obovoidea), Keissleriella acacia (≡ Pleurophoma acaciae), K. italicum (≡ Pleurophoma italica), K. ossicula (≡ Pleurophoma ossicola), K. pleurospora (≡ Phoma pleurospora), Phaeosphaeria brachylaenae (≡ Didymocyrtis brachylaenae), P. pini (≡ Didymocyrtis pini) and P. septata (≡ Didymocyrtis septata). Additionally, we report 31 new host records from medicinal plants and six new geographical records for China and Thailand. We also resolved inter-generic synonymy for three species. A reference specimen is designated for Diplocladiella taurina. Detailed descriptions and illustrations of all these taxa are provided.
The Invisible Barrier: Unraveling the Link between Air Pollution and settlement intention of floating population
Authors: Cao Dongmei , Liao Yujia , Guo Ce , Xu Xiaofan
Published: October 2024

This paper utilizes 2017 dynamic monitoring data of China's floating population and matches it with air pollution data from 287 prefecture-level cities to construct a Probit model. The study aims to investigate the effects and pathways of air pollution on the settlement intention of floating populations. The research findings are as follows: Firstly, air pollution significantly affects the settlement intention of floating populations, with an increase in air pollution concentration leading to a notable decrease in their intent to reside. Secondly, the impact of air pollution on the settlement intention of floating populations varies based on their personal characteristics and regional features. Those with longer years of residence, higher education levels, and better air quality in their hometowns tend to be more sensitive to air pollution. Thirdly, air pollution reduces the settlement intention of floating populations by affecting their physical health. This study enriches the relevant research on environmental factors' influence on the settlement intention of floating populations, and it provides insights for the government to formulate talent attraction policies from an environmental governance perspective.
Reliability and validity of the Chinese version of the Oxford Positive Self Scale in Chinese Nursing Undergraduates
Authors: tang wenlong , wang weiwei , zhong gaoxiang , wei zhidan , ding zhangyi , zhang qianya , lu sun , mao rong , li yuanzhen , cui huixia
Published: October 2024

Background According to the recent report of the China National Mental Health Survey, young Chinese people are a high-risk group for depression among the entire adult population, and the detection rate of depression risk in Chinese individuals aged 18–24 years is as high as 24.1%, which is significantly higher than that of other age groups. Hence, it is essential to study the mental health of the Chinese youth population. People with a positive self-mindset tend to have a higher sense of self-efficacy, and when these people encounter adversities and face challenges in their lives, they are more active in finding approaches and mobilizing resources to combat them. Currently, most research studies on the positive self-concept in Chinese people have focused on the users of social media networks, and there is a lack of research on the positive self-concept level in the general population. Although individual self-concept scales, mainly the Adversity Beliefs Scale and the Self-Concept Scale, have been used in previous research, these scales do not directly measure an individual’s beliefs about the positive self-concept. Therefore, in the present study, the Oxford Positive Self Scale (OxPos) was translated into Chinese, and the psychometric properties of the Chinese version were assessed in nursing undergraduates as the research subjects.Method This study was conducted from April 2024 to August 2024 by recruiting undergraduate nursing students from freshman year to junior year of an undergraduate college. A total of 514 valid questionnaires were collected. The Chinese translation process of the OxPos, including both forward and backward translations, strictly adhered to the Brislin’s model and was followed by necessary modifications. Item analyses were performed using critical ratios and item-total correlation coefficients. Validity assessments included content validity, structural validity, and validity scale correlation validity. Scale reliability was determined by Cronbach’s alpha coefficient, retest reliability, and split-half reliability coefficient.Results The Chinese OxPos version included 24 entries in 4 dimensions with a cumulative variance contribution rate of 87.27%. The content validity index of the scale for this survey was 0.875. Exploratory factor analysis showed that the Chinese OxPos version was consistent with the dimensional division of the original scale. The validation factor analysis showed a satisfactory fit index. The Cronbach’s alpha coefficient, re-test reliability, and split-half reliability coefficient of the Chinese OxPos version were 0.935, 0.978, and 0.845, respectively.Conclusion After a rigorous process of adaptation to the Chinese context, the Chinese version of OxPos showed good psychometric properties. The scale proved helpful as a research tool for assessing the positive self-concept level in the Chinese cultural context.
The significant impact of hot isostatic pressing on the corrosion behaviour of Ti-6Al-4V alloy prepared by electron beam powder bed fusion
Authors: Zheng Hongyu , Bai Yun , Hou Wentao , Zhai Zirong , Zhang Lai-Chang , Li Shujun , Yang Rui
Published: October 2024

This work investigated the effect of hot isostatic pressing (HIP) on the corrosion behavior of Ti-6Al-4V samples prepared by electron beam powder bed fusion (EB-PBF). After the HIP treatment, the TiO2 content decreased but the growth rate of passivation films increased, leading to increase in internal defect density, thereby degrading the corrosion resistance. Amongst the different factors impacted by HIP including pore defects, β-phase, texture and morphology of α-phase, the morphology of α-phase played a dominant role in determining the corrosion performance of EB-PBF processed alloy.
Histone H4K16 Acetylation Modification regulated autophagy and apoptosis in PC12 cells injured by OGD
Authors: Lin Jie-Min , Li Kun-Hui , Zhou Lin-Quan , Chen De-Hui , Zhao Xin , Li Wen-wen , Liu Wenge
Published: October 2024

Background
Autophagy maintains the homeostasis of the internal environment by clearing misfolded proteins and damaged organelles, which can reduce neuronal apoptosis in the early stage of spinal cord injury (SCI) and promote neural function recovery. Previous studies have shown that decreased acetylation modification of histone H4 lysine16 acetylation (H4K16ac) induces the expression of downstream autophagy genes. However, the role of H4K16 acetylation modification and its impact on autophagy and apoptosis in the early stage of SCI remains unclear. This study aimed to determine the relationship between H4K16ac and autophagy, apoptosis in the early stage of SCI, and the effects of regulating H4K16ac on autophagy and apoptosis.
Methods
In this study, the state of nerve cells after spinal cord injury was simulated by PC12 cells injured by OGD, and the content of histone H4K16 was interfered to investigate the effects of autophagy and apoptosis of nerve cells.
Results
The results indicate that promoting H4K16 acetylation levels significantly increases neuronal damage, and is associated with the inhibition of early autophagy and promotion of apoptosis.
Conclusion
These findings suggest that histone H4K16ac may provide a new therapeutic target for treating neuronal damage after SCI.
Rhizosphere secondary metabolites quinolones and benzoxazinoid alleviate continuous cropping obstacles of strawberry
Authors: Cai Bingbing , Xue Zhanjun , Yang Lina , Liu Yike , Xu Zihan , Li Qingyun
Published: October 2024

Alterations to the rhizosphere microenvironment following the continuous cropping of strawberry can result in substantial declines in yield and quality. Plant rhizosphere produces a wide variety of secondary metabolites, which play important roles in regulating plant growth and development. According to the chemical structure and biosynthesis pathways, secondary metabolites can be devided into different groups, and some of these metabolites have been demonstrated to hold ecological significance and responsing to biotic and abiotic stresses. But how this type of feedback affects plant growth is unknown. In this research, strawberry cultivar ‘Santa’ under continuous cropping for 10 years at different cultivation media were used. We assessed the pH value and conductivity of medium solution, dry weight of roots and analyzed the secondery metabolites using ultra performance liquid chromatography (UPLC). After adding cow dung, we detected a significant lower conductivity of medium solution. In addition, after adding goat manure, we detected a significant heigher dry weight of roots. A total of 736 metabolites from 11 classes were detected across all samples. The 20 most significant differentially accumulated metabolites with variable importance in projection scores greater than 1 in each treatment included 17 terpenoids, 5 organic acids, 5 nucleotides and derivatives, 4 lipids, 2 alkaloids, 2 flavonoids, 1 phenolic acid, and 4 others. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed that these metabolites were significantly enriched in the following pathways: metabolic pathways, nucleotide metabolism, and biosynthesis of secondary metabolites. Statistical approach showed that the rhizosphere secondary metabolites quinolones and benzoxazinoid were two key compounds that alleviate continuous cropping obstacles of strawberry. If this phenomenon holds true across different soils and environments, this strategy could be a powerful and tractable application to alleviate continuous cropping obstacles.
Who makes it to the top? Differential rewards to personality across gender and occupation in the UK
Authors: Josten By Cecily , Lordan Grace
Published: October 2024

This study tests whether personality traits are legitimately rewarded in the labour market or whether there are differing rewards across gender that cannot be explained with productivity. We investigate if personality traits affect the likelihood of making it to the top income quintile within an occupation differently by gender using UK Household Longitudinal data. We find that being agreeable hurts men more than women across a majority of occupations, which points at the role of gender norms for wages. Further, female legislators and senior officials who are conscientious, extraverted, neurotic and open are more likely to be among the top earners than men. Other than that, we find small gender differences in personality rewards.