bluuebunny/crossref_metadata_2025 huggingface dataset:
Physical Inactivity as a Wicked Problem in Sub-Sahara Africa: Overview and Recommendations
Authors: Onagbiye Sunday O. , Bester Petra
Published: March 2022

Physical Activity (PA) is a public health concern and has been listed as the fourth primary risk feature for Non-Communicable Diseases (NCDs). Physical inactivity has been understood as one of the wicked problems of the 21st century. The worldwide load of illnesses connected with physical inactivity is significant. This paper, from a viewpoint, discusses what can be done to reduce the wicked problem of physical inactivity in sub-Saharan African (SSA) nations. Physical inactivity is a wicked problem because it avoids direct suppression and is difficult to resolve in a way that is modest or absolute. Physical inactivity may be comprehended as the continuum of any decline in a person’s movement that yields a reduction in energy outflow regarding basal level, which is a direct opposite of physical activity definition. Physical inactivity has been documented several years ago and was believed that regular light and moderate exercise could present confrontation with disease and counter physical deterioration. Despite PA’s defensive factors for the avoidance and management of the foremost NCDs, other important NCD risk factors, and psychological health (WHO, 2002), many people still do not participate. In sub-Saharan Africa, physical inactivity and low levels of physical activity were among the 10 top-ranked risk factors for the attributable burden of disease. One review paper recently published documents that the prevalence of physical inactivity stands at twenty-two percent, which is close to the global average of twenty-seven percent and has been projected to increase in the nearest decades. Therefore, confronting “wicked problems” of physical inactivity in the sub-Sahara Africa region requires an urgent collaborative transdisciplinary approach backed up with good policy implementation and resources.
Prevalence of Anemia among Chronic Myeloid Leukemia Patients Treated
with Imatinib: A Evidence-based Meta-analysis
Authors: Sharma Manju , Singh Avinash Kumar , Kumar Anoop , Agrawal Narendra , Bhurani Dinesh , Ahmed Rayaz
Published: March 2022

Backgrounds:

Imatinib is one of the tyrosine kinase inhibitors used for the treatment of
chronic myeloid leukemia (CML) patients. The exact association of imatinib with anemia in CML patients
is still unclear.

Aim:

The current study aimed to find the prevalence of anemia in chronic myeloid leukemia patients
treated with imatinib.

Methods:

The relevant articles were searched in PubMed, Google scholar, and Clinical trials registries
till 31st July, 2021. The quality of the articles was assessed using the Newcastle-Ottawa Scale. The
prevalence rate with 95% CI was calculated using StatsDirect Statistical analysis software V.3.

Results:

A total of 18 studies containing 3537 patients were found relevant for the analysis. The
pooled prevalence of anemia in CML was found to be 34% (95% CI: 23%-46%). However, the heterogeneity
among studies was found to be high.

Conclusion:

The monitoring of hemoglobin levels and identifying the cause of anemia are major concerns
for the CML patients treated with Imatinib.
Economy management in developing countries: from creativity to innovation perspective
Authors: Yemima Yemima , Mohdari Mohdari , Afriana Rizki Amalia , Kusumawardani Vivi Pancasari
Published: March 2022

This paper examines and discusses economic and financial development strategies in developing countries, starting from creativity efforts to creating sustainable innovations. A series of data collections were collected from national and international publications to discuss those published 12 years ago. Then we conducted an in-depth study of the collected data with a phenomenological approach to strengthen the data as findings that will be used as answers to research hypotheses with high standards of validity and reliability. By considering the data we have reviewed and discussing the interrelationships between existing variables, we finally conclude that economic governance in developing countries can be carried out with high creativity to give birth to the latest innovations to achieve economic progress and prosperity throughout the country. It is hoped that these findings and recommendations can support the implementation of future studies and applications in both academic and work contexts.
ACCOUNTING PERSPECTIVE ON THE ISLAMIC-DRIVEN ACCOUNTABILITY IN A TRADITIONAL ISLAMIC ORGANISATION IN JAVA
Authors: Prasetio Januar Eko , Triyuwono Iwan , Sukoharsono Eko Ganis , Purwanti Lilik
Published: March 2022

Purpose â€”Â  This study explores an accounting perspective on the Islamic-driven accountability in Gus Miekâ€™s Jantiko Mantab community, a traditional Islamic organization in Java. The Jantiko Mantab is an East Java-based community initiated by KH. Hamim Tohari Jazuli (Gus Miek) in 1970s. Regardless of the unique and controversial method of Gus Miek, this community was selected as the object due to its progressive development in the Islamic movement on the number of followers especially in grass root and marginalized communities in Java. The study focuses on two main public activities of the Jantiko Mantab, which are continuously held from one place to other places, namely Al Quran recitation (Semaan) and praising Allah using holy sentences (Dzikrul Ghofilin) in the congregation.Design/methodology/approach â€”Â  This study is qualitative research with a spiritual paradigm approach and uses a spiritual perspective analysis method through tawasul, zikir, and syir (pray). The study is conducted through bibliography reviews, interviews, and direct observations.Findings â€”Â  The results of this study showed Religious activities within the community were experienced to gain a comprehensive understanding of the founder, leader, and member perspectives on the organizationâ€™s accountability. Accountability in Jantiko Mantab was understood as a formal aspect of accounting, such as financial reports, and also performed and nurtured in accordance to the human task as Khalifatullah fil Ardh. The concept of Khalifatullah fil ArdhÂ is embedded in their community and considered as the accountability uniqueness of Jantiko Mantab.Practical implications â€” Semaan Al-Qurâ€™an and Dzikrul Ghofilin of Jantiko Mantab should make a change in interpreting the concept of accountability that is currently loaded with capitalist interests by incorporating Islamic values sourced from Al Qur'an and hadiths.Originality/value â€” This Islamic value, which is also delivered and reflected by their leaders, is likely to drive the member perception of the organization's accountability.Â Keywords â€”Â  Accountability, Islamic value, Islamic organization, Indonesia.Â Paper type â€” Case Study
Dissociated Vertical-Torsional Nystagmus in Vestibular Nucleus Lesion
Authors: Kim Hyun-Sung , Oh Eun Hye , Choi Jae-Hwan
Published: March 2022

Dissociated vertical-torsional nystagmus is a unique form of nystagmus characterized by conjugate torsional but disparate vertical components. It has been mainly reported in internuclear ophthalmoplegia or medial medullary lesion involving the medial longitudinal fasciculus (MLF). The patterns of the nystagmus may be explained by a disruption of vestibulo-ocular reflex pathways from vertical semicircular canal or utriculo-ocular reflex within the MLF, but it is debatable. We described a dissociated upbeat-torsional nystagmus in a patient with vestibular nucleus infarction without involvement of MLF.
Auto-Pattern Recognition for Diagnosis in Benign Paroxysmal Positional Vertigo Using Principal Component Analysis: A Preliminary Study
Authors: Gwon O-Hyeon , Kong Tae Hoon , Key Jaehong , Yang Sejung , Seo Young Joon
Published: March 2022

Objectives: The aim of this study was to develop a filtering algorithm for raw nystagmus images and a diagnostic assistive algorithm using a principal component analysis (PCA) to distinguish the different types of benign paroxysmal positional vertigo (BPPV).Methods: Fifteen video clips of clinical data with typical nystagmus patterns of BPPV (13 cases) and with normal nystamgmus (two cases) were preprocessed when applied the thresholding, morphology operation, residual noise filtering, and center point extraction stages. We analyzed multiple data clusters in a single frame via a PCA; in addition, we statistically analyzed the horizontal and vertical components of the main vector among the multiple data clusters in the canalolithiasis of the lateral semicircular canal (LSCC) and the posterior semicircular canal (PSCC).Results: We obtained a clear imaginary pupil and data on the fast phases and slow phases after preprocessing the images. For a normal patient, a round shape of clustered dots was observed. Patients with LSCC showed an elongated horizontal shape, whereas patients with PSCC showed an oval shape at the (x, y) coordinates. The scalar values (mm) of the horizontal component of the main vector when performing a PCA between the LSCC- and PSCC-BPPV were substantially different (102.08±20.11 vs. 32.36±12.52 mm, respectively; p=0.0012). Additionally, the salar ratio of horizontal to vertical components in LSCC and PSCC exhibited a significant difference (16.11±10.74 mm vs. 2.61±1.07 mm, respectively; p=0.0023).Conclusions: The data of a white simulated imaginary pupil without any background noise can be a separate monitoring option, which can aid clinicians in determining the types of BPPV exhibited. Therefore, this analysis algorithm will provide assistive information for diagnosis of BPPV to clinicians.
A study of interests and science process skills
Authors: Budiarti Retni Sulistiyoning , Kurniawan Dwi Agus , Rivani Putri Ayu
Published: March 2022

This study aims to determine the differences and the relationship between interest and science process skills with 80 female students and 56 male students. This research uses quantitative methods so that this research is more systematic and objective. The sampling technique used in this study used simple random sampling. Analysis of the data used using hypotheses in the form of normality, linearity and homogeneity tests and assumption tests in the form of T test and correlation test. From the results of the T test and correlation test, it was found that there were differences and relationships between the sexes in the interests and skills of class VIIA and VIIB. In this case it is evidenced by a significant value 0.05. Thus, the higher the interest of students, the higher the skills of students according to their gender. It can be said that success can be seen from the level of understanding, mastery of the material, and student achievement. The higher the understanding and mastery as well as learning achievement, the higher the level of learning success.
Pelatihan Aplikasi Inventaris Barang Untuk Poliklinik Pemulung Di Kawasan Pemakaman Rangkah, Surabaya
Authors: Effendy Faried , Nuqoba Barry , Justitia Army , Werdinigsih Indah
Published: March 2022

Poliklinik ‘Pemulung” merupakan poliklinik yang berdiri atas kerjasama YDSF (Yayasan Dana Sosial Al-Falah) dan BSMI (Bulan Sabit Merah Indonesia). Pokliklinik ini memberikan jasa dokter dan obat secara gratis kepada masyarakat pemulung di wilayah makam rangkah. Permasalahan yang terjadi adalah kurangnya penguasaan admin poliklinik pada proses inventarisasi. Admin poliklinik merupakan warga sekitar yang dibina secara otodidak oleh pihak dokter BSMI, sehingga pengetahuan dan wawasan beliau masih dirasa kurang. Beberapa proses yang tidak efektif diantaranya: proses pencatatan yang hanya dilakukan pada selembar kertas/ buku yang sering mengakibatkan ketidak-sinkronan antara data dengan aset, hilangnya aset karena peminjaman aset yang tidak dicatat, buku catatan aset rusak/ hilang sehingga aset harus didata ulang. Kegiatan pengabdian masyarakat ini menggunakan pendekatan Focus Group Discussion (FGD) yang meliputi pelatihan, pembinaan dan evaluasi untuk memantau keberhasilan kegiatan menggunakan metode observasi. Materi yang disampaikan meliputi proses inventarisasi yang benar dan optimal dengan menggunakan Sistem Informasi Inventaris Barang, pembuatan laporan sederhana dengan Microsoft Excel. Hasil kegiatan pengabdian masyarakat ini yaitu peningkatan wawasan dan kompetensi admin poliklinik di bidang Inventaris Barang.
Pelatihan Pembuatan Media Interaktif untuk Pembelajaran Fisika Bermakna di Masa Pandemi untuk Guru Fisika SMA Kabupaten Kediri
Authors: Hanatan Ardiana , Purwaningsih Endang , Suwasono Purbo , Kusairi Sentot
Published: March 2022

Kegiatan pengabdian kepada masyarakat yang dilakukan bertujuan untuk memberikan pelatihan pembuatan media interaktif pada para guru Fisika yang tergabung dalam Musyawarah Guru Mata Pelajaran Fisika (MGMP) Kabupaten Kediri. Diberikan pula pelatihan mengenai moodle, pendalaman materi Fisika, dan juga Technological, Pedagogical, Content Knowledge (TPACK). Pelatihan dilakukan secara blended learning selama 32 jam yang diikuti oleh 36 peserta. Peserta memberikan respon positif terhadap pelatihan yang dilakukan. Terdapat perbedaan yang signifikan dalam persiapan pembelajaran jarak jauh yang dilakukan oleh guru sebelum diadakannya pelatihan dan setelah diadakannya pelatihan. Antusiasme para peserta yang tinggi tercermin dalam feedback yang diberikan bahwa diperlukan adanya pelatihan lanjutan.
Pemasangan Panel Sel Surya (Lampu Listrik) di Kawasan Obyek Wisata Gunung Buthak Desa Tlogokotes, Kecamatan Bagelen, Kabupaten Purworejo
Authors: Jatmoko Dwi Dwi , Suyitno Suyitno , Primartadi Aci , Susanto Arif , Laksono Agung
Published: March 2022

Nuansa alam pegunungan yang masih alami di kawasan obyek wisata Gunung Buthak, Desa Tlogokotes, Kecamatan Bagelen, Kabupaten Purworejo. Gunung Buthak sudah memberikan daya tarik melalui pemandangan alamnya yang indah kepada siapa pun yang berniat mendatanginya. Untuk tujuan itu, mau tidak mau tampilan Gunung Buthak yang di musim kemarau atau hujan khususnya dimalam hari mengalami kurang nyamannya pengunjung, karena kondisi yang tidak ada lampu atau sulitnya listrik masuk ke pegunungan. Strategi untuk solusi hal itu, adalah menggunakan panel surya untuk membuat lampu listrik agar bermanfaat dalam penerangan malam hari. Kegiatan Pengabdian kepada masyarakat ini bertujuan membuat dan menerapkan pembangkit listrik tenaga panel sel surya untuk memberikan penerangan jalan di kawasan obyek wisata Gunung Buthak sehingga secara kenyamanan dan keamanan. Pengabdian masyarakat ini menggunakan metode terstruktur dengan dimulai teori tentang panel sel surya, dilanjutkan dengan praktikum yang didampingi oleh praktisi dengan konsep praktikum langsung untuk membuat lampu listrik secara langsung. Pemanfaatan teknologi tepat guna dengan Pemasangan lampu listrik sel surya sangat membantu dalam memberikan penerangan di daerah pegunungan khususnya gunung buthak. Hasil dari pengabdian masyarakat ini mendapatkan tanggapan baik dan positif, mulai dari respon perangkat desa, kepuasan masyarakat sekitar, dan dilihat dari quisioner yang telah di berikan kepada pengunjung obyek wisata.
Upaya Pencegahan Penyebaran Covid-19 dan Penguatan Kekebalan Tubuh Melalui Pelatihan Pengembangan Imunosuplemen Berbasis Potensi Lokal
Authors: Pertiwi Kartika Ratna , Kuswandi Paramita Cahyaningrum , Rahayu Tutiek , Putri Rizka Apriyani
Published: March 2022

Kader kesehatan merupakan salah satu wujud kontribusi masyarakat dalam upaya pemeliharaan kesehatan dan pemberantasan penyakit, termasuk Covid-19. Program ini bertujuan memberikan pengetahuan kepada kader kesehatan Gondanglegi, Wedomartani, Yogyakarta tentang upaya pencegahan Covid-19 dengan penguatan sistem imun menggunakan bahan-bahan alam potensi lokal, sekaligus penguatan keterampilan budidaya tanaman rimpang serta pengolahan produknya menjadi imunosuplemen. Metode kegiatan berupa persiapan, pelaksanaan berupa ceramah, diskusi dan simulasi dilanjutkan praktek perwakilan, serta ditutup dengan evaluasi keberhasilan berupa lomba. Hasil kegiatan ini berupa kehadiran peserta (91,7%), pencapaian skor pengetahuan kader (90) serta skor persepsi kader (90). Kreativitas kader dalam penerapan pengetahuan mengenai herbal imunosuplemen terlihat dari produk yang dikembangkan berupa biskuit jahe, puding telang, dan minuman herbal “jaselem” dan “jagujek”. Penilaian produk meliputi komposisi bahan imunomodulator, proses pembuatan dan tampilan produk. Hasilnya didapatkan rerata skor 88,67 (jahe), 85,83 (puding telang), 85,1 (jaselem) serta 87,56 (jagujek). Kendala pembatasan kegiatan dalam kurun pengabdian disiasati dengan pembatasan jumlah pertemuan, jumlah partisipan serta durasi waktu kegiatan. Program ini diharapkan dapat dilanjutkan kader dengan dukungan padukuhan dan puskesmas setempat untuk meningkatkan bukan hanya kesehatan tapi juga perekonomian masyarakat.
Pendampingan KSM Bidang Sains Terintegrasi Agama Melalui Pendekatan Hybrid Di Masa Pandemi Covid-19
Authors: Yuliana Ika Farida , Fatayah Fatayah , Priyasmika Rendy , Purwanto Kriesna Kharisma , Rohmah Rosyidah Syafaatur , Maulidah Tsalitsatul
Published: March 2022

Pandemi virus Corona yang melanda Indonesia sejak tahun 2020 memberikan dampak nyata khususnya pada bidang Pendidikan. Kondisi ini mengakibatkan adanya pembatasan kegiatan bimbingan tatap muka dalam pendampingan KSM. Tujuan kegiatan pengabdian ini adalah untuk memberikan ketrampilan kepada siswa tentang penalaran jawaban dari soal dan pemahaman materi sains yang menyeluruh dikaitkan dengan agama serta nilai keislaman. Metode yang dilakukan dalam kegiatan ini adalah melalui pendampingan menggunakan pendekatan pembelajaran hybrid, yaitu pendampingan melalui tatap muka langsung dan secara daring menggunakan Grup Whatsapp. Kegiatan pendampingan ini dilakukan pada kelas V dan VI di MI Al-Khoiriyah 1 Delegan. Jumlah siswa sasaran adalah 4 orang siswa yang terpilih dan terbagi dalam kelompok IPA dan Matematika untuk mewakili dalam kegiatan KSM. Hasil dari pendampingan menunjukkan peningkatan penguasaan konsep materi dan ketrampilan menjawab siswa yang ditunjukkan dengan nilai rata-rata 82. Selain itu siswa juga dapat lebih memahami konsep sains yang diberikan dan integrasinya dengan agama.  Kata kunci: pendampingan; KSM; pendekatan hybrid; covid-19.
PENGEMBANGAN MODUL SISTEM PENDINGIN UNTUK KELAS XI DI UPT SMK NEGERI 8 PALEMBANG
Authors: Wijaya Herli Padli
Published: March 2022

Penelitian ini bertujuan untuk: 1) mengembangkan produk modul sistem pendingin, 2) mengetahui kelayakan modul sistem pendingin menurut ahli media, 3) mengetahui kelayakan modul sistem pendingin menurut para ahli materi, 4) mengetahui tanggapan guru dan peserta didik pada modul sistem pendingin. Penelitian ini merupakan penelitian Research and Development dengan metode pengembangan ADDIE menurut Branch.  Penelitian ini menggunakan teknik pengumpulan data dengan metode observasi, wawancara dan angket.  Hasil penelitian dan pengembangan ini adalah: 1) menghasilkan produk akhir berupa modul perawatan sistem pendingin dengan spesifikasi yaitu : memiliki judul “Modul Perawatan Sistem Pendingin”, bahan ajar cetak dengan ukuran kertas A4 dan modul menggunakan kompetensi dasar (KD) 3 sistem pendingin. 2) kelayakan modul  mendapatkan skor 3,95 dari penilaian ahli materi termasuk kategori “sangat layak”, mendapatkan skor 3,36 dari penilaian ahli media termasuk kategori “sangat layak”, mendapatkan skor 3,72 dan 3,76 dari penilaian guru pada aspek materi dan aspek media termasuk kategori “sangat mudah dipahami” dan “sangat menarik”, mendapatkan skor 3,46 dari penilaian peserta didik sebagai pengguna termasuk kategori “sangat bermanfaat”.
Virtual Reality in Clinical Practice and Research: Viewpoint on Novel Applications for Nursing
Authors: Son Hyojin , Ross Alyson , Mendoza-Tirado Elizabeth , Lee Lena Jumin
Published: March 2022

Virtual reality is a novel technology that provides users with an immersive experience in 3D virtual environments. The use of virtual reality is expanding in the medical and nursing settings to support treatment and promote wellness. Nursing has primarily used virtual reality for nursing education, but nurses might incorporate this technology into clinical practice to enhance treatment experience of patients and caregivers. Thus, it is important for nurses to understand what virtual reality and its features are, how this technology has been used in the health care field, and what future efforts are needed in practice and research for this technology to benefit nursing. In this article, we provide a brief orientation to virtual reality, describe the current application of this technology in multiple clinical scenarios, and present implications for future clinical practice and research in nursing.
Developing a Dietary Lifestyle Ontology to Improve the Interoperability of Dietary Data: Proof-of-Concept Study
Authors: Kim Hyeoneui , Jung Jinsun , Choi Jisung
Published: March 2022

Background

Dietary habits offer crucial information on one's health and form a considerable part of the patient-generated health data. Dietary data are collected through various channels and formats; thus, interoperability is a significant challenge to reusing this type of data. The vast scope of dietary concepts and the colloquial expression style add difficulty to standardizing the data. The interoperability issues of dietary data can be addressed through Common Data Elements with metadata annotation to some extent. However, making culture-specific dietary habits and questionnaire-based dietary assessment data interoperable still requires substantial efforts.

Objective

The main goal of this study was to address the interoperability challenge of questionnaire-based dietary data from different cultural backgrounds by combining ontological curation and metadata annotation of dietary concepts. Specifically, this study aimed to develop a Dietary Lifestyle Ontology (DILON) and demonstrate the improved interoperability of questionnaire-based dietary data by annotating its main semantics with DILON.

Methods

By analyzing 1158 dietary assessment data elements (367 in Korean and 791 in English), 515 dietary concepts were extracted and used to construct DILON. To demonstrate the utility of DILON in addressing the interoperability challenges of questionnaire-based multicultural dietary data, we developed 10 competency questions that asked to identify data elements sharing the same dietary topics and assessment properties. We instantiated 68 data elements on dietary habits selected from Korean and English questionnaires and annotated them with DILON to answer the competency questions. We translated the competency questions into Semantic Query-Enhanced Web Rule Language and reviewed the query results for accuracy.

Results

DILON was built with 262 concept classes and validated with ontology validation tools. A small overlap (72 concepts) in the concepts extracted from the questionnaires in 2 languages indicates that we need to pay closer attention to representing culture-specific dietary concepts. The Semantic Query-Enhanced Web Rule Language queries reflecting the 10 competency questions yielded correct results.

Conclusions

Ensuring the interoperability of dietary lifestyle data is a demanding task due to its vast scope and variations in expression. This study demonstrated that we could improve the interoperability of dietary data generated in different cultural contexts and expressed in various styles by annotating their core semantics with DILON.
Geosocial Networking App Use Associated With Sexual Risk Behavior and Pre-exposure Prophylaxis Use Among Gay, Bisexual, and Other Men Who Have Sex With Men: Cross-sectional Web-Based Survey
Authors: Gibson Laurel P , Kramer Emily B , Bryan Angela D
Published: March 2022

Background

In the United States, geosocial networking (GSN) apps (ie, mobile dating apps) have become central to dating and sexual interactions in recent years. Among gay, bisexual, and other men who have sex with men (GBM), these apps play an important role in reducing barriers and facilitating partner seeking. However, despite these benefits, there are concerns that these apps may facilitate risky sexual behavior and transmission of sexually transmitted infections (STIs) among GBM.

Objective

This study aimed to examine the association between GSN app use and sexual risk in a US sample of GBM.

Methods

Using a cross-sectional design, respondents (N=223) completed a web-based survey assessing their use of GSN apps, sexual risk and protective behaviors, HIV serostatus, and previous STI diagnoses.

Results

Respondents were aged 21-78 (mean 31.90, SD 10.06) years and 69.5% (155/223) were non-Hispanic White. The sample included respondents from 40 states and the District of Columbia. Nearly half (104/223, 47%) of the participants reported using GSN apps. GSN users were more likely to report past-year condomless anal intercourse (P<.001), 3 or more sexual partners in the previous year (P<.001), and a previous STI diagnosis (P=.001) than nonusers. GSN users also reported more frequent use of recreational drugs before sex (P=.001), alcohol use before sex (P<.001), and cannabis use before sex (P=.01). Interestingly, GSN users were also more likely to report having ever taken an HIV test (P<.001) and using pre-exposure prophylaxis (P=.03). The rates of HIV seropositivity did not differ significantly between GSN users and nonusers (P=.53). Among the subset of GSN users, 38 participants reported using only GBM-specific GSN apps (eg, Grindr), whereas 27 participants reported using only sexuality nonspecific GSN apps (eg, Tinder). Exclusive users of GBM–specific apps reported more frequent recreational drug use before sex (P=.01) and were also more likely to report past-year condomless anal intercourse (P<.001), 3 or more sexual partners in the previous year (P=.004), a previous STI diagnosis (P=.002), and HIV testing (P=.003). Alcohol use before sex, cannabis use before sex, pre-exposure prophylaxis use, and HIV rates were similar between both groups (P>.11).

Conclusions

The findings suggest that GSN apps may be a useful pathway for interventions aimed at reducing STI risk in GBM. Future prospective studies should examine how risk levels change after the initiation of GSN app use.
Acceptance of an Internet-Based Team Development Tool Aimed at Improving Work-Related Well-being in Nurses: Cross-sectional Study
Authors: Broetje Sylvia , Bauer Georg F , Jenny Gregor J
Published: March 2022

Background

Workplace health interventions can produce beneficial health- and business-related outcomes. However, such interventions have traditionally focused on lifestyle behaviors of individuals, mostly not considering the role of working conditions. The wecoach intervention is an internet-based tool that combines both a digital and a participatory team development approach aimed at addressing critical job demands and resources as key aspects of health-promoting working conditions. Nursing staff are particularly affected by challenging working conditions and could potentially benefit greatly. Understanding the acceptance of novel workplace health promotion approaches is a critical precursor to their successful implementation and use.

Objective

This study aims to examine the factors influencing the acceptance of a digitally supported team development tool among nurse managers.

Methods

A sample of 32 nurse managers from 3 German-speaking countries tested wecoach and completed our online questionnaire. Hypotheses were based on the unified theory of acceptance and use of technology (UTAUT) and the organizational health development (OHD) model and were tested using multiple regression analyses.

Results

Our analyses found that merely capacities on the team level (CapTeam) significantly contributed to the acceptance of wecoach, although only after the other variables were excluded in the stepwise multiple regression analysis. The UTAUT predictors were unable to add significant variance explanation beyond that, and their inclusion masked the contribution of CapTeam.

Conclusions

For the acceptance of a digitally supported participatory tool, the fit with the team, its culture, and its motivation are of critical importance, while aspects proposed by traditional acceptance models, such as the UTAUT, may not be applicable.
Discovering long COVID symptom patterns: Association rule mining and sentiment analysis in social media tweets (Preprint)
Authors: Matharaarachchi Surani , Domaratzki Mike , Katz Alan , Muthukumarana Saman
Published: March 2022

BACKGROUND

The COVID-19 pandemic is a significant public health crisis that negatively affects human health and well-being. As a result of being infected with the Coronavirus, patients can experience long-term health effects called long COVID Syndrome (LCS). Multiple symptoms characterize this syndrome, and it is crucial to identify these symptoms as they may negatively impact patients’ day-to-day lives. Breathlessness, fatigue, and brain fog are the three most common continuing and debilitating symptoms that long COVID patients have reported, often months after the onset of COVID-19.

OBJECTIVE

This study aimed to understand the patterns and behavior of long COVID symptoms reported by patients on the Twitter social media platform, which is vital to improving our understanding of long COVID.

METHODS

Long COVID-related Twitter data were collected from 1 May 2020 to 31 December 2021. We used association rule mining (ARM) techniques to identify frequent symptoms and establish relationships between symptoms among long COVID patients in Twitter social media discussions. The highest confidence level-based detection was used to determine the most significant rules with 10% minimum confidence and 0.01% minimum support with a positive lift.

RESULTS

The most frequent symptoms in our study included brain fog (26%), fatigue (17%), breathing/lung issues (16%), heart issues (10%), flu symptoms (9%), depression (7%) and general pains (6%). Loss of smell and taste, cold, cough, chest pain, fever, headache, and arm pain emerged in two to six percent of long COVID patients. Further, the highest confidence level-based detection successfully demonstrates the potential of association analysis and the apriori algorithm to establish patterns to explore 57 meaningful relationship rules among long COVID symptoms. The strongest relationship revealed that patients with lung/breathing problems and loss of taste are likely to have the loss of smell with 77% confidence.

CONCLUSIONS

There are very active social media discussions that could support the growing understanding of the COVID-19 and its long-term impact. This enables a potential field of research to analyze the behavior of the LCS. Exploratory data analysis using Natural Language Processing (NLP) methods revealed the symptoms and medical conditions related to long COVID discussions on the Twitter social media platform. Using apriori algorithm-based association rules, we determined interesting and meaningful relationships between symptoms.

CLINICALTRIAL
Methodology of Baidu Index for Infodemiology and Infoveillance (Preprint)
Authors: Ma Ming , Li Hui , Zhu Mengli , Lin Tao , Song Turun
Published: March 2022

BACKGROUND

Baidu Index is an open tool that provides information about trends and changes in online interest in selected keywords and topics over time. The analysis of Baidu queries has become a valuable tool for researchers to explore and predict human behavior, disease occurrence and outbreaks. Although Baidu Index has been applied to many fields in China, there is no research to describe a specific methodology framework of Baidu Index in detail.

OBJECTIVE

Make a retrospective analysis of the application of Baidu Index in the medical field, and summarize the methodology of Baidu Index for infodemiology and infoveillance.

METHODS

We searched the PubMed database for articles from January 2003 to January 2022 with the keywords: ‘Baidu Index’, and the methods of applying Baidu Index in all articles were reviewed and summarized. Combined with the operational guidance from the Baidu Index official website and our previous research, we explained the methodology of applying Baidu Index.

RESULTS

A total of 134 articles were detected. According to the types of diseases concerned in the article, they are roughly divided into: covid-19 (21/134, 15.67%), influenza (8/134, 5.97%), infectious diseases (15/134, 11.19%), sexually transmitted diseases (4/134, 2.99%), others (25/134, 18.66%), and unrelated articles (61/134, 45.52%). The ‘search index’, ‘demand map’, and ‘user portrait’ are the three main parts of Baidu Index. Each part corresponds to different data types and reflects different characteristics.

CONCLUSIONS

The methodological framework for research using the Baidu index presented in this paper is essential to provide guidance for research using the Baidu index in health assessment and, more importantly, to help researchers, health officials, and organizations avoid common errors that jeopardize the validity of results.

CLINICALTRIAL

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Apa yang direkomendasikan apoteker untuk tatalaksana diare akut pada anak? Sebuah survei di wilayah timur Kota Surabaya
Authors: Ningsih Linda Fidya , Setiadi Adji Prayitno , Rahem Abdul , Brata Cecilia , Wibowo Yosi Irawati , Setiawan Eko , Halim Steven Victoria
Published: March 2022

Appropiate recommendation provided by pharmacists is considered as a crucial factors to prevent morbidity and mortality among children with acute diarrhea in the community. This study aimed to determine the type and the appropriateness of recommendations provided by the community pharmacists in the eastern part of Surabaya to children presenting with acute diarrhea. This was cross-sectional study conducted by using a questionnaire consisting of questions about participants’ characteristics and a case of acute diarrhea in children without complications and other “alarm symptoms” requiring medical referral. The appropriate recommendation for the case was to give a combination of oral rehydration solution (ORS) and zinc with or without other recommendations. Data were analyzed descriptively using SPSS version 22. A total of 84 pharmacists provided consent to be participants in this study. The majority of participants (73,81%) were pharmacists manager and more than 50% of them completed pharmacist professional degree between 2010 and 2019. Type of pharmacists’ recommendations were further classified as: medical referral, provision of medicine, laboratory testing, and non-pharmacology treatment. The most provided recommendations were provision of medicine (97,62%) with or without other recommendations. Medical referral were recommended by 22 pharmacists (26,19%). Of the total participants, 13,09% provided appropriate recommendations. Findings of this study indicate the necessity to optimise the role of community pharmacists in managing acute diarrhea in children. Further study to identify the needs of community pharmacists, either conducted with qualitative or quantitative approach, is required as the key step before implementing further intervention.
Antioxidants and Antityrosinase Activity of Ethanolic Basil Leaves Extract (Ocimum americanum L.) and Eygenol
Authors: Handoyo Dio Damara , Girsang Ermi , Nasution Ali Napiah , Lister I Nyoman Ehrich
Published: March 2022

Harm effect from UV light, both UV-A and UV-B is contributing as a disease trigger and has an impact on human health. To investigate the bioactive compound, antioxidant, and the potential of basil leaves as antiaging sources particularly as the tyrosinase inhibitor. This study used phytochemical screening for the bioactive compound, DPPH scavenging activity for antioxidant assay, and tyrosinase inhibition activity for the antiaging property. The phytochemical screening shows that the basil leaves extract has flavonoid, saponin, phenol, steroid, and alkaloid. The basil leaves extract has lower antioxidant activity (20.55 ± 0.04 μg/mL) compared with eugenol (2.44 ± 0.26 μg/mL) through DPPH scavenging activity. The basil leaves extract (35.59 ± 0.83 μg/mL) has lower antiaging activity particularly as antityrosinase activity compared with eugenol (10.87 ± 0.41 μg/mL). Our findings suggest that basil leaves can be used as an antioxidant and antiaging source, particularly as a tyrosinase inhibitor.
Gel Formulation from Ethanol Extract of The Leaf of White Guava (Psidium guajava L.)
Authors: Setyawaty Rety , Gustin Gustin , Setiyabudi Ragil
Published: March 2022

White guava is a plant that can grow easily in Indonesia. As a source of vitamin C, white guava leaves have been used as antidiarrheal drugs. Some studies state that white guava leaves contain antioxidants. Aside from having a selling value, white guava leaves are also used as raw materials for facial cosmetics, namely as raw materials for gel. Flavonoids are a large family of plant secondary metabolites that have various and amazing biological functions, including as antioxidants. The study aims to determine the gel preparation formulation of the white guava leaf extract (Psidium guajava L.) as a good antioxidant and the characteristics of the preparation. To extract the active substance in simplicia, maceration is used by using ethanol extract processes. The gel making uses a CMC-Na base. Formulation I uses a concentration of CMC-Na 0.1 gram. Formulation II uses a concentration of CMC-Na 0.3 grams. Formulation III uses a concentration CMC-Na 0.6 gram. The main raw material is 0.2 grams of white guava leaf ethanol extract for each formulation. The maceration process uses 70% ethanol. 250 grams of white guava leaves are used. The yield obtained was 13.92%. The gel product was analyzed organoleptic test, pH test, dispersion test, homogeneity test, and adhesion test. The results showed that the CMC-Na 0.1-grams, 0.3 grams CMC-Na, and 0.6-grams CMC-Na had a distinctive odor of white guava leaves, brownish color, and thick concentration. The gelling product is homogeneous and pH of 6. The formulations under CMC-Na 0.6 grams have good dispersibility. All formulations have good adhesion. The adhesion is more than 4 seconds. The conclusions are the formulation with CMC-Na 0.6 grams fulfills the requirements for topical gel preparation.
Ethanolic Extract of Pluchea indica Less leaf Increases Serum Growth Hormone in Lactating Rats
Authors: Syarif Rul Afiyah , Anggorowati Nungki , Munawaroh Mia , Wahyuningsih Mae Sri Hartati
Published: March 2022

The objectives of the study were to evaluate the effect of ethanolic extract of P. indica Less leaf (EPI) on serum growth hormone (GH), milk yield, body weight gain of dams, and dam’s organ weight in lactating rats. A total of 25 lactating rats with six pups were randomized and distributed to one of five treatments (control (RO water), standard (domperidone 2,5 mg/kg BW/day), EPI 250 (250 mg/kg BW of EPI), EPI 500 (500 mg/kg BW of EPI), and EPI 750 (750 mg/kg BW of EPI)). The treatment was administered daily starting from the 2nd until the 15th day of lactation. On the 16th day serum growth hormone level, body and organ weight of rats were measured. Serum GH levels in the EPI 750 group (1963.25 ± 360.91 pg/µL) increased significantly compared to the domperidone (409.46 ± 28.80 pg/µL) and the control group (723.40 ± 95.78 pg/µL, p0.05). There was significant body weight gain in the EPI 750 group compared with the domperidone group. There was no significant difference in organ weight gain in each group. The study revealed that ethanolic extract of P. indica Less leaf can increase serum growth hormone in lactating rats.
The Effects of Green Betel Leaf (Piper betle) Extract Eye Drops on the Number of Staphylococcus aureus Colonies in Conjunctivitis Wistar Rats Model (Rattus novergicus)
Authors: Nur Mahira Aisyah Putri , Sudaryanto Sudaryanto , Lestari Endang Sri , Kresnoadi Erwin
Published: March 2022

Irrational use of antibiotics can cause resistance to some diseases such as bacterial conjunctivitis caused by Staphylococcus aureus. Previous research said that green betel leaf (Piper betle) contains antimicrobial compounds such as eugenol, cavalry, tannins, saponins, and flavonoids which also have antiseptic power as well as antibiotics. This study aims to prove the decrease in the number of Staphylococcus aureus colonies after giving green betel leaf eye drops (Piper betle) to conjunctivitis Wistar rats (Rattus norvegicus). This research was true experimental with a pretest-posttest control group design. 25 male white Wistar rats as objects were selected by simple random sampling and grouped into 5 groups randomly. The rats were given Staphylococcus aureus, control group K+ was given 0.5% levofloxacin eye drops, and K- was given aquadest as a comparison. Treatment groups P1, P2, and P3 were given different concentrations of betel leaf eye drops. Swab pretest was done 3 days after the rats were inoculated with Staphylococcus aureus and swab post-test was done 5 days after the rats were given green betel leaf eye drops, the calculation of Staphylococcus aureus bacteria colonies used the Total Plate Count (TPC) method. There was a significant decrease (p<0.05) in the number of bacterial colonies for K-, K+, P1, P2, and P3 groups. In addition, there was a significant difference (p<0.05) between K+ with P1 and K+ with P3. There was a decrease in the number of Staphylococcus aureus for all groups of conjunctivitis Wistar rats (Rattus norvegicus)
Accelerated Stability Test of Snakehead Fish Extract (Channa striata) and Kelulut Honey (heterotrigona itama) Ointment Combination with Tween 80 and Span 80 as an Emulsifying Agent
Authors: Taurina Wintari , Andrie Mohamad , Pratama Taufik Nanda
Published: March 2022

The combination of Snakehead Fish and Kelulut Honey has activity in accelerating the wound healing process. The ointment with active ingredients of Snakehead Fish extract and Kelulut Honey showed separation from the active ingredient and its base. The addition of tween 80 and span 80 is expected to increase the stability of the ointment preparation by keeping the water-phase droplets distributed uniformly on the ointment base. This study aimed to determine the effect of adding Tween 80 and Span 80 on the stability of the ointment preparation. The ointment was made by varying Tween 80 and span 80 by 2,5%: 5%: 7,5% and control (active ingredients without the addition of tween 80 and Span 80) as a comparison. The preparation was subjected to an accelerated stability test using a temperature of 40 ° ± 2 ° C / Relative humidity 75% ± 5% for 28 days by observing the organoleptic test, adhesion, spreadability, homogeneity test, pH test, and protection power. The data obtained were analyzed statistically using One Way Anova. The analysis showed that the addition of tween 80 and span 80 with a total concentration of 5% and 7,5% had a significant effect in increasing the spreadability, decreasing adhesion, and reducing the pH of the preparation. Formulas that meet the requirements in this study are F2 and F3, which have an average spreadability of 5,11 cm and 5,25 cm, adhesion of 96 seconds and 51 seconds, and pH of 6,02 and 5,02.
Modeling and Optimization of Mitragyna speciosa Extraction using Box Behnken Design
Authors: Rusydan Azka M. , Lukitaningsih Endang , Fakhrudin Nanang
Published: March 2022

The extraction of kratom (M. speciosa) leaf powder was optimized with preliminary extraction to be further optimized with the Box-Behnken experimental design. The individual and interactive effects of process variables (sample-to-solvent ratio, extraction time, solvent concentration) were assessed. The preliminary extraction results showed that ultrasound-assisted extraction (UAE) and methanol were chosen for further optimization. The experimental data were analyzed by Pareto analysis of variance (ANOVA) and second-order polynomial models were developed using multiple regression analysis. The model developed showed a good fit with the experimental data with a high coefficient of correlation (R2) and predictive ability (predicted R2). An optimization study was performed and the optimal extraction conditions were sample-to-solvent ratio value 1.5:10; extraction time of 10 minutes, and methanol concentration of 100%.
An Investigation on the Influence of Various Biochemical Tenderness Factors on Eight Different Bovine Muscles
Authors: Hammond Peang A. , Chun Colin K. Y. , Wu Wan Jun , Welter Amelia A. , O'Quinn Travis G. , Magnin-Bissel Geraldine , Geisbrecht Erika R. , Chao Michael D.
Published: March 2022

This study’s objective was to understand the relationships between biochemical tenderness components andobjective/sensory measure of tenderness of 8 muscles from beef carcasses. Longissimus thoracis (LT), pectoralis profundus (PP), supraspinatus, triceps brachii (TB), gluteus medius (GM), rectus abdominus (RA), rectus femoris, and semitendinosus (ST) were collected from 10 USDA upper 2/3 Choice beef carcasses and assigned to a 2- or 21-d aging period (n=160). Troponin-T degradation, desmin degradation, sarcomere length, collagen content, mature collagen crosslink density, intramuscular lipid content, pH, Warner-Bratzler Shear Force (WBSF), and trained sensory panel analyses were measured. A Pearson correlation analysis was conducted to determine the relationship between each tenderness contributor measured in this study with WBSF or the overall tenderness evaluated by the trained panelist for each of the 8 muscles.In addition, multivariate regression models were constructed to confirm this relationship. The results showed that muscle anatomical locations and physiological functions driven by muscle fiber types may explain some of the biochemical/tenderness differences found in this study. The correlation analysis showed that each muscle had a specific tenderness factor(s)that contributed to the overall tenderness. For instance, tenderness for LT, TB, GM, RA, and ST may be influenced more by proteolytic degradation, while the collagen characteristics may primarily influence tenderness for PP. Also, lipid content has a significant influence on GM tenderness. Finally, the multivariate regression model showed that almost all of the biochemical measurements conducted in this study contributed to overall tenderness to some degree across muscles.Increasing the knowledge base on the various tenderness components’ level of contribution will allow end-users to develop specific tenderness management strategies to ensure consistent tenderness in beef products.
PRESENCE OF EXTRACURRICULAR ACTIVITIES AND THE NUMBER OF STUDENTS ATTENDING EXTRACURRICULAR ACTIVITIES/SECTIONS
Authors: Čolović Danijela
Published: March 2022

The aim of the research is to explore and compare the participation of students in sections, and their interest (realization, motivation, satisfaction), as well as of parents in extracurricular activities. Google Questionnaires (for students and parents) were used as research instruments. The sample of respondents was formed by surveying 8 students of both genders from each of totally 30 class (N=376 in total), as well as their parents (N=376). Finally, 341 questionnaires were fulfilled by students, and 310 by their parents. The analysis acknowledged that extracurricular activities/sections include significantly more first-class students than second-cycle students. There is more registered students in comparison to those who regularly attend classes, especially at the second cycle of education. In certain aspects of the realization of sections students are satisfied, but there is a possibility for improvements in work. When planning section classes, it is important to envision the ability to place students in the teaching role, developing student self-reliance and self-confidence, but also to encourage peer learning and all students to engage in activities.