bluuebunny/crossref_metadata_2025 huggingface dataset:
Key Techniques of Ultra-Low Signal to Noise Ratio Data Processing, a Case Study in Sarawak, Malaysia
Authors: Du H. , Zhang H. , Chen Y. , Ru C. Siu , Isa B. Bin , Ming T. Tai
Published: February 2025

Seismic exploration in coastal areas often encounters significant challenges due to complex near-surface conditions. In areas such as Sarawak, Malaysia, these challenges are exacerbated by rapid changes in the thickness of weathered layers, geological irregularities, and variations in near-surface velocities, all of which contribute to severe seismic data distortions. Such degradation in data quality can complicate static corrections and velocity picking during processing, potentially resulting in "no data" zones. Such distortions increase the risk of misinterpretation, ultimately impeding effective hydrocarbon exploration and production.

Conventional seismic processing methods have not fully addressed these issues in Sarawak, leading to suboptimal exploration outcomes. The legacy processing results from this region exhibit a lack of clarity in the structural imaging, and in many cases, entire sections are devoid of usable seismic reflections. The complex near-surface conditions caused significantly both long-wavelength and short-wavelength static correction challenges and the absorption effects of inconsistent wavelet behavior, while the extremely low signal-to-noise ratio further complicates accurate subsurface interpretation.

To address these challenges, this paper presents a new reprocessing approach that integrates advanced tomographic static correction, relative amplitude preserved denoising techniques, and combined surface-consistent processing to tackle inconsistencies of wavelet in Sarawak. By focusing on issues related to statics, wavelet consistency, and signal-to-noise ratio, this study demonstrates that these methods can significantly enhance subsurface imaging accuracy, supporting more reliable exploration in the region.
A Report Generation System for Well Logging Industry Based on Large Language Model and Retrieval Augmented Generation
Authors: Li Pin , Liu Yubo , Zhou Jun , Zhang Juan , Zhou Yuange
Published: February 2025

In the well logging industry, interpretation reports are critical for evaluating subsurface geological conditions, yet their preparation is often time-consuming and inconsistent due to reliance on human experts. This paper presents a novel methodology that leverages the generative capabilities of large language models (LLMs) to automate the creation of well logging interpretation reports, significantly improving efficiency. Central to our system is an LLM-based content generation module that sources and composes report sections. To address data privacy and cost concerns, we utilize open-source LLMs deployed locally. Recognizing the limitations of general LLMs in handling field-specific inquiries, retrieval-augmented generation (RAG) framework is employed to integrate well logging domain knowledge, ensuring contextually relevant outputs. Through experimentation, it is found that prompt phrasing significantly influences LLM performance, prompting the use of prompt engineering techniques to optimize results. A blind review of 100 generated reports by well logging experts demonstrates the system's ability to produce complete, clear and coherent reports. These findings highlight the transformative potential of customized LLMs, capable of generating reports in just 10 minutes—compared to 4 hours manually—thereby revolutionizing labor-intensive processes and significantly improving work efficiency in the well logging industry.
Field-Testing Verified Digital Models for Monitoring Drillstring Fatigue Induced by Rotating-Bending, Vibration, and Stick-Slip
Authors: Yang B. , Chen W. , Du M. H. , Irsa G. , Virene P. , Bandi M. , Mohd Najmi N. Fahusnaza Nik
Published: February 2025

Fatigue life of a drillstring is affected by rotating-bending, vibration, and stick-slip during field operations. Tracking the drillstring fatigue life to accurately determine the remaining useful life (RUL) is critical in the prognostic health management (PHM) of the drillstring. It will provide a quantified basis to help prevent costly downhole drillstring failures, improve drilling efficiency, and implement a condition-based maintenance program.

Digital models are created to monitor the drillstring fatigue life during downhole operations. In the process, the operation data are used as the inputs to a finite element analysis (FEA) -based module of the digital models to calculate the downhole dynamic parameters. These parameters are then used to evaluate the fatigue life of the drillstring consumed by rotating-bending, vibration, and stick-slip. For rotating-bending fatigue, FEA is used to simulate component stress/strain distribution, and the strain-based Coffin-Manson method is applied to calculate the fatigue life. The vibration-induced fatigue is evaluated by generating different vibration modes and simulating the final fatigue damage by combining these modes according to field run parameters. The stick-slip-induced fatigue is calculated by correlating the stick-slip levels with baseline torque. The total fatigue damage to the component is obtained by integrating all these three fatigue estimation results based on the failure modes of the component.

The digital models were applied with eight drillstrings for more than 50 field runs. A fatigue-prone component of the hydraulic jar in the drillstring was used as an example to simulate the fatigue accumulative history from its brand-new state to the final fatigue failure. These cases covered the scenarios of fatigue failures induced by rotating-bending, vibration, and stick-slip. Among all these cases, more than 80% of the failures happened when the simulated RUL was less than 30%. Rotating-bending fatigue accounts for 14% of all related failures, vibration fatigue for 51%, and stick-slip fatigue for 35%. It was also found that at least 75% of the failures can be prevented through tracking the fatigue induced by rotating-bending, vibration, and stick-slip.

The digital models developed through this work help improve the drillstring operation reliability and prevent costly downhole tool failures while maximizing the asset usage, which also enhances the operation sustainability. The methodology can be populated to other components across the drillstring and improve the total PHM processes of the operations.
Efficient Surrogate Modeling for Subsurface Flow Simulation Using Multi-Fidelity Data with Physical Constraints
Authors: Cui Jiawei , Sun Wenyue , Li Hangyu , Liu Shuyang
Published: February 2025

In subsurface flow simulation, data-driven deep learning surrogate models have emerged as a promising alternative to traditional simulation methods. However, a major challenge is the large amount of high-fidelity simulation data required for training, and purely data-driven flow surrogate models often lack theoretical support, limiting their applicability to engineering problems. In this study, we propose an efficient surrogate model construction method that integrates physical constraints and multi-fidelity training data. The process begins with pre-training a deep learning model using a large amount of low-cost, low-fidelity data to effectively initialize network parameters. The pre-trained model is then fine-tuned with a smaller amount of high-fidelity data. Throughout the training, physical losses constrain the model to adhere to physical principles. For the case considered here, this approach reduces the need for high-fidelity data by approximately 83% compared to traditional training methods without compromising predictive accuracy. Additionally, incorporating physical loss during model training e ffectively enhances the surrogate model's predictive accuracy, with physical loss reduced by nearly 70% compared to purely data-driven training. The method employs the Jacobian matrix to aid in model training, significantly reducing the computational cost of physical losses. Overall, this surrogate model construction method addresses the challenges of obtaining training data and the lack of physical support in surrogate models, providing reliable support for complex reservoir development decisions.
Fast AI Fault Prediction Using Sparsely Interpreted Labels
Authors: Xiong Wei , Li Lei , Cui Jingbin , Zhang Xiaofang , Dai Lihua , Xu Chen
Published: February 2025

Faults play a crucial role in the exploration and development of oil and gas resources. In recent years, deep learning algorithms for fault interpretation have shown signs of progress and are still in a rapid development stage. Since most of the research at this stage uses 3D synthetic data, ignoring the complex geological structure of the field data. This paper focus on the training data issue, using true fault sticks as labels. An interactive training data generation tool is utilized to automatically establish pairs of seismic data and fault labels, forming a 2D training data set characterized by local fault features. In the model training phase, a lightweight 2D UNETR++ architecture is trained using 2D true data to enhance fault recognition accuracy. Additionally, to tackle the problem of discontinuities results from 2D training data, an optimized U-Net model is used to improve the continuity. The proposed intelligent fault prediction method based on real labels can be applied for rapid prediction and identification of major faults, offering reliable data for automated fault interpretation and subsequent structural modeling.
Enhancing Sustainable Water Management in Hydraulic Fracturing with Degradable Fiber Integration
Authors: Khetib T. , Annane B. , Khelkhal H. , Glaznev I. , Enkababian P.
Published: February 2025

This study investigates the application of degradable fibers in hydraulic fracturing to improve fluid efficiency, reduce leak-off, and enhance effective fracture conductivity across various well and reservoir conditions. By incorporating Fracturing Loss Additives (FLAs) such as degradable fibers into the PAD stage, this research demonstrates significant reductions in leak-off coefficients and increased fluid efficiency, allowing more efficient use of fracturing fluids and supporting better proppant placement within the fractures. Five wells within distinct locations lithologies, fluid types, and fracture parameters were analyzed, and fiber concentrations were tailored to specific conditions. Results show that fluid efficiency improved by up to 30%, and effective conductivity gains were observed in most cases. The introduction of degradable fibers also led to an average water reduction of 20-30%, contributing to sustainability by enabling operators to achieve desired fracturing outcomes with reduced water usage. This study highlights the potential of degradable fibers to optimize hydraulic fracturing operations by maximizing fluid preservation and enhancing fracture performance, thereby offering a sustainable alternative for resource conservation in hydraulic fracturing operations.
Synergizing Planning and Technology: Achieve World-Class Drilling Performance: A Suriname Deep-Water Exploration Project Case Study
Authors: Norani M. R. , Ezzaty N. , Hafizi R. M. , Abidin F. Z. , Salleh M. N. , Wahab A. A. , Ibrahim A. S. , Moran L. A. , Johnston D. , Ramroop V. , Pariag E. , Mendes A. , Daniel N. A. , Rambaran K. , Millan A. J. , Huang W. , Noronha M. , Kumar A. , El-Khoury J. , Gendur J. , Martinez A. , Velez E. I. , Restrepo J. , Hayson L. , Espinola B.
Published: February 2025

PETRONAS Suriname explored for oil in Block 52 in the deep waters off Suriname. This block covers an area of 4,749 km2. The project, located north of Paramaribo, Suriname's capital city, within the prospective Suriname-Guyana basin, contains three wells. The project required drilling 5-km-deep exploration wells to gather essential subsurface data. The data will serve to determine the existence of oil and the length of the prospective oil reservoir.

The engineering design and implementation stages involved many challenges because the offset wells in nearby blocks experienced well control incidents, low rate of penetration (ROP), stuck wireline string events due to unconsolidated sands, and wellbore instability issues. All of these issues were major obstacles from planning and execution perspectives.

The engineering team, along with the integration service provider, collaborated in the design phase and used innovative engineering solutions for bit selections, bottomhole assemblies design, and optimum drilling fluid selection along with the use of the latest technologies for formation evaluation. Each component of the well design was analyzed to ensure optimum design and a safe operational limit with extensive risk assessment of all potential hazards along with prevention and alleviation plans.
Beyond Digital Twins: Evolution of Transient Hole Cleaning Models to Enable Higher Levels of Automation
Authors: Arévalo Pedro
Published: February 2025

Modeling cuttings transport is one of the most prominent examples of modern well engineering enabling drilling automation. An accurate model of the behavior of cuttings from its creation to its exit of the wellbore provides valuable insights into well control and process stability. Such information serves as reference for higher layers of data processing and interpretation that correlate modeled behavior with actual measurements in real-time to identify anomalies and opportunities to improve processes. A common example is the identification of stuck-pipe conditions via correlation of modeled cuttings transport and density measurements downhole.

The transient model subject of this paper is a physics-based drift-flux cuttings transport model part of a larger digital twin of the wellbore. This model has been deployed in several locations worldwide as the center of a holistic hole cleaning advisory application. Some of the most sensitive deliverables of this model are the concentration of cuttings, its behavior as they are transported to surface, and the estimation of time and flow rate to transport the cuttings to surface. This kind of context information has enabled users to make informed decisions to maintain the health of the operation and avoid stuck-pipe events. Users can better decide where and for how long to circulate the wellbore after drilling a section to reduce cleaning time without endangering the formation and avoiding stuck-pipe events.

The hole cleaning application provides a central and concise visualization to highlight regions with high cuttings concentration and increasing risk of stuck-pipe events. This paper presents a few steps of the evolution of transient hole cleaning models deployed in real-time and how its presence as part of a wider drilling automation portfolio influences the adoption of drilling automation overall. Some field deployments worldwide are taken as example to discuss adoption of the service. The range of applications deploying the transient hole cleaning model span across high-pressure, high-temperature environments, managed pressure drilling (MPD), long lateral sections, among others.
Cementing a High CO2 Gas Injection Well Offshore West Africa: Three-Step Design Approach to Help Ensure Long-Term Integrity
Authors: Tomassi S. , Terentyev D. , Massie I. A. , Krokhin D. , Hernandez R.
Published: February 2025

An operator in the deepwater environment offshore West Africa tasked the cement service company to develop a solution to help ensure long-term integrity of the annular cement placed behind the 7-in. liner in a gas injector well. This well was designed as a dry gas injector, with up to 15 mol% carbon dioxide (CO2) in the gas composition and anticipated injection rates between 80 and 100 MMscf/D throughout a well's life in excess of 20 years. Exposure to this dynamic CO2 environment, along with extreme temperature and pressure changes through the injection cycles, created significant risks for the cement sheath's integrity. Furthermore, the well section would penetrate a lower karstic carbonate structure prone to losses. The cement service company had to ensure proper cement placement and design a system that would maintain integrity and achieve zonal isolation throughout the life of the well.

The cement service company implemented a three-step approach to design a solution tailored to address these specific challenges. In step one, finite element analysis (FEA) modeling identified the key mechanical properties of the cement system necessary to withstand the stresses of operations throughout the life of the well. Step two focused on the cement system design. A system with reduced Portland cement content and additional components to reduce permeability was selected to enhance the cement's resistance to degradation under dynamic CO2 exposure while the mechanical requirements defined by the FEA model were achieved. The narrow pore-fracture gradient window required the design of a cement system with a density as low as 10.9 lbm/gal to maintain equivalent circulating density (ECD) less than the pressure threshold where losses were expected in the carbonate structure. In the final step, three-dimensional (3D) fluid displacement modeling software evaluated the key parameters required to achieve competent cement placement during the operation.

The cement operation was successfully executed per the design. A total of 46 bbl of 10.9-lbm/gal cement was prepared in the batch mixer and pumped downhole without losses. Liner rotation was maintained throughout the cement operation, and cement returns were observed at the shakers during post-operation circulation, which validated full cement coverage of the 7-in. liner to the top of the liner. Once sufficient time had elapsed for the cement to cure, the 7-in. liner passed the pressure test. After the 7-in. upper completion tubing was run, the 7-in. liner was successfully perforated with tubing conveyed perforating (TCP) guns and no unwanted fluid production was encountered, which confirmed successful zonal isolation. Approximately 18 months after suspension, gas injection at the well began successfully, with daily injection rates of up to 100 MMscf achieved.
Robust System - Connector as Enabler for Multiple Sand Screens Installed Downhole in Oil Well with Height Clearance Issue
Authors: Lee Q. , Norddin S. , Reekhi G. S. , Habib N. M. , Berok S. M. James , Islamov R. , Hasbi N. , Sulhi A. , Omar M. B. , Barat J. , Zin Z. M. , Tham K. , Subari I. , Maluan L. , Foo N. , Madon B. , Chung L. , McClean C. A. , Wilson S.
Published: February 2025

Field T, located 40 km west of Bintulu in offshore Sarawak, Malaysia, spans 50 km² and consists of four clastic reservoir groups (H, I, J, and K) first discovered in 1962, with oil production commencing in 1979. The field's geological setting includes a complex depositional environment of lower and upper coastal formations, characterized by significant faults. Field management strategy was divided the field into three areas: West, Central, and East. In fact, after 40 years of production, 10% of the 98 strings currently closed due to unconsolidated sand and reservoir depletion. This paper presents a case study on Well A, which began production in January 2019, achieving an average gross rate of 600 bbl/d with no water cut or sand production until mid-2021. Following increased sand production, the well was beaned down, thus halving its production potential. To address this, a thru-tubing remedial sand control approach was adopted. Initial attempts to install a conventional 10-ft thru-tubing sand screen (TTSS) were obstructed by a helideck overhead, prompting a shift to custom-made 5-ft TTSS. While this adaptation alleviated installation challenges, it raised concerns regarding potential screen plugging. The conventional installation process typically involved extensive planning and risk assessments, contributing to significant production deferment due to resource uncertainties and helideck constraints. To mitigate delays, the Connector system was evaluated and selected for this production enhancement (PE) job, enabling a streamlined installation process. The successful implementation of Connector system as a pioneering application in Malaysia water enabled connection of two custom-made 5-ft TTSS downhole resulted in a 30% production enhancement for Well A, with sustained production and no sand production issues for over 1.5 years. This PE job also realized a cost savings of approximately $0.35 million by eliminating helideck skidding. The findings underscore the importance of innovative solutions in enhancing production efficiency while effectively managing operational costs in challenging offshore environments.
New Records of Extended Reach Drilling in China Offshore
Authors: Weiguo Zhang , Deli Gao , Ke Ning , De Yan , Tianyun Gao , Nan Huang , Deshmukh Vikrant
Published: February 2025

More than just providing an overview of the longest extended reach drilling (ERD) well recently accomplished in China offshore, with a total depth of 9508m and an ERD ratio of 4.46, the paper will delve deep into key elements such as well design, drilling technologies and practices implemented, which contribute to the success of a well that is approaching the limits of feasibility. Post-job learning and thinking will also be discussed.

To drill challenging ERD wells, sophisticated engineering is a fundamental step. A detailed analysis of offset wells and geological risks would enhance the practicality and instructiveness of the engineering design. Technology innovation is of great importance in drilling the well safely and efficiently. Downhole mechanical measurements were analyzed in real time. The methodology and workflow were developed by utilizing downhole axial loading, torsional loading and pressure-while-drilling data in conjunction with surface drilling parameters, to assess downhole conditions. The new MWD (Measurement While Drilling) tool is taking survey while drilling, eliminating the need for static survey time, reducing downhole risks and saving rig time (Lowdon, 2021).

5 million capital expenditure saving was achieved by eliminating the need for titanium alloy drill pipe through comprehensive drilling string design and rig sizing evaluation. The well was drilled and cased successfully, creating several new records in China. These records include the longest production well, the longest 12.25in open hole section of 5124 meters, and the deepest 9-5/8in casing setting depth at 8125 meters. Sophisticated engineering, fit-for-purpose drilling technologies and customized solutions contributed to delivering the record ERD well in China. The successful delivery of the well demonstrated the overall strength and accuracy of the well plan developed, as well as the technologies and computer models incorporated. Real-time downhole mechanical measurements analysis played a crucial role in monitoring drilling operations and ensuring the well was drilled without any surprises. Advanced Rotary Steerable Systems (RSS) and MWD tools are essential for achieving directional control and drilling a smooth wellbore, which are critical for achieving low Friction Factor (FF) and ensuring successful casing installation.

The paper will demonstrate how fit-for-purpose engineering solutions and technologies are delivering a well that is approaching the limit of feasibility. And comprehensive analysis of drilling mechanical measurements can significantly enhance the transparency of downhole conditions, narrow down hypotheses, and enable timely implementation of corresponding measures for complex downhole situations.
In-fill Wells in CBM - Development Strategy Optimization
Authors: Swain S. P. , Maiti D. , Kumar S. , Seetharaman S. K.
Published: February 2025

Coal Bed Methane (CBM) being low margin business the techno-commercial viability is key to achieve the success of the project. To ensure such success it is absolutely necessary to understand the ever changing dynamics of the CBM reservoir and achieve optimize the well placement as suitable for the production phase of the field. Accordingly, the field development plan goes through constant strategic evaluation and evolution along the life of a coal bed methane project.

CBM field production performance largely depends on 3 key criterion – Gas content, saturation and permeability. Higher gas content contributes towards the resource volume and permeability impacts production volume as well as the sustenance of the production. Saturation in CBM is defined by the ratio of the gas present in a seam to the maximum storage capacity of the seam. Saturation impacts the required depressurization to reach the critical desorption pressure i.e. point of gas breakout. Dewatering is the key method for depressurization in CBM; more the seams are saturated less of dewatering would be required to bring the pressure down for the gas to release.

Coal seams by nature are very heterogeneous and further heterogeneity gets introduced to the reservoir with production. At different phases from exploration to production the reservoir behaviour and subsequent well behaviour varies significantly and understanding the same is key to optimize the well placement and completion strategy to achieve the ultimate goal of maximum production. Initial development plan is designed based on the primary core well and production testing. As the filed grows with time, new areas are ventured in step-out philosophy often the field performance varies significantly from the initial projection. Also the reservoir behaviour changes significantly from initial dewatering phase where water is the primary fluid phase to the production phase where the relative permeability of gas becomes the key contributing factor. These changing dynamics of the reservoir plays a key role in development strategy of a CBM field as it matures with time. During the well interference in the middle or later drainage stages optimally placed in-fill wells can impact the effective permeability significantly and benefits from the dewatering already done to achieve faster gas break out and sustained production.
Prediction of Drilling Efficiency Sorting for Each Run Using Machine Learning Methods
Authors: MA J. , SONG Z. H. , LI Y. C. , Liu B.
Published: February 2025

At present, research and application of artificial intelligence in drilling operations inside China and abroad still remain at a stage of engineering prediction based on limited downhole sensor data and laboratory environment simulation under instantaneous level time scale and fundamental simulation levels, making it difficult to be widely applicable for drilling performance forecasting and establish effective connections with financial plans. This paper carries out research on three core issues and proposes solutions: how to classify drilling efficiency, how to select suitable sample features, and how to make prediction to ensure the accuracy of the final classification results meets reference standards. The study is expected to assist financial personnel in shortening the tedious process of learning about correlating business in drilling investment planning and exploring more scientific and widely accepted methods in the practice of refined cost management and cost prediction in the national oil and gas industry's integration of business and finance. Results show that drilling run data with high accessibility and applicability can be used for drilling efficiency classification research. Target encoding can preserve string features without causing dimension catastrophe, provide better predictive evaluation indicators across all methods, and voting learning is found to be a more suitable machine learning method in this approach.
Pharmacogenetics and pharmacogenomics in COVID-19
Authors: Berni Luigi Chermont , Flexa Carla Victória Barbosa , Mesquita Amanda Fonseca , Santos Alanna Lorena Pimentel dos , Brito Giovana Pereira Lobato , Paes Victor Leno Silva , Coelho Erik William Farias , Oliveira Rita de Cássia Silva
Published: February 2025

Objective: To analyze the relationship between pharmacogenetics and pharmacogenomics with Covid-19. Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, using the PubMed and SciELO databases. Case, observational and bench studies in English and Portuguese were included, from December 2019 to December 2022. Results: Population genetic differences influence the effects of drugs on Covid-19. Studies highlight the importance of considering metabolic disorders, such as diabetes and dyslipidemia, as risk factors. The pharmacogenetic interaction between medications for these disorders and treatments for Covid-19 must be evaluated. Genetic polymorphisms, such as GNB3 c.825C>T, present conflicting results, indicating the complexity of genetic interactions. Other studies analyze genes such as ACE2, CYP2C19 and variants in IFITM3, revealing associations and challenges in interpreting results. Final considerations: This review highlights that population genetic distinctions influence the severity of Covid-19 and the response to pharmacological treatments. Polymorphisms in specific genes show varying results, indicating the need for more comprehensive studies. The use of medicines still lack evidence for the management of Covid-19 as it may present risks to patients, highlighting the importance of pharmacogenetics and pharmacogenomics in personalizing treatments.
Efeitos da auriculoterapia na qualidade de vida e em níveis de ansiedade e depressão em estudantes de fonoaudiologia
Authors: Ortiz Suelen Rocha , Balsamo Gisiê Mello , Mezzomo Carolina Lisbôa
Published: February 2025

Objetivo: Verificar os efeitos da auriculoterapia no desempenho acadêmico, nos níveis de ansiedade e na qualidade de vida dos estudantes do Curso de Fonoaudiologia de uma Universidade Pública do Sul do Brasil. Métodos:  Esta pesquisa caracteriza-se como de campo, quantitativa, prospectiva e transversal realizada por amostra de conveniência. Participaram do estudo 23 estudantes os quais foram divididos em dois grupos, controle e estudo. Resultados: O grupo controle não apresentou diferença significativa na comparação entre os períodos pré e pós intervenção.  No  grupo estudo, obteve-se diferença significativa entre os períodos pré e pós auriculoterapia no domínio físico e na depressão. Na comparação dos grupos pós intervenção, obteve-se  melhora nos domínios físico, psicológico e meio ambiente. Encontrou-se correlação significativa  entre as variáveis de qualidade de vida no período pós intervenção entre o domínio psicológico e físico, entre a depressão e o domínio das relações sociais e também entre a depressão e meio ambiente Conclusão: A auriculoterapia apresenta-se como uma prática integrativa eficaz na melhoria do bem estar dos estudantes no que se refere a alguns domínios de qualidade de vida, e com resultados favoráveis na diminuição dos sintomas relacionados a ansiedade e depressão.
MINOR TRUTH OF GIRL MATH ON MENTAL ACCOUNTING PERSPECTIVE
Authors: Zahrah Niswatin , Soeherman Bonnie
Published: February 2025

ABSTRACT
The "Girl Math" trend has become widespread and viral, seemingly supporting the idea that women tend to be impulsive when shopping. This research discusses the phenomenon in the context of mental accounting. This research aims to construct a conceptual model of girl math from the mental accounting perspective. This research uses the interpretivism paradigm to explore the meaning of the reality being studied through the triangulation of interview methods, observation, and information analysis through social media, the internet, and other relevant articles. This study found that almost all-girl math trends encourage impulsive buying behavior. They have a logic and mental accounting that differ from the general rational standards. Girl math has its own rationalization. The mindset of girls math occurs due to internal and external factors. Internal factors include emotions, the availability of economic resources, and self-control. External factors include community roles, product attraction, and media framing. Girl math could become another truth, but it is merely the truth of a minority.
ABSTRAK
Tren “Girl Math” menjadi marak dan viral dimana tren ini seolah mendukung anggapan bahwa perempuan cenderung impulsif dalam berbelanja. Penelitian ini membahas fenomena tersebut dalam konteks mental accounting. Penelitian ini bertujuan untuk mengkonstruk sebuah model konseptual girl math dalam perspektif mental accounting. Penelitian ini menggunakan paradigma interpretivisme untuk menggali makna dari realita yang diteliti melalui triangulasi metode wawancara, observasi, dan analisis informasi melalui media sosial, internet serta artikel lain yang relevan. Penelitian ini menemukan hampir seluruh tren girl math mendorong terjadinya impulsive buying behavior. Mereka memiliki logika dan mental accounting yang berbeda dengan standar rasional umum. Girl math memiliki rasionalisasinya sendiri. Mindset girl math terjadi akibat faktor internal dan eksternal. Faktor internal meliputi emosi, kesediaan sumber daya ekonomi, dan pengendalian diri. Sedangkan faktor eksternal terdiri atas peran komunitas, atraksi produk, dan framing media. Girl math bisa saja menjadi kebenaran yang lain, namun kebenaran sebatas kebenaran minoritas.
Comparative analysis of the effect of riboflavin solutions on the corneal thickness of rabbits
Authors:   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia, Bikbov M.M. , Khalimov A.R. ,   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia, Usubov E.L. ,   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia, Babushkin A.E. ,   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia, Kazakbaekva G.M. ,   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia, Nizamutdinova A.M. ,   Ufa Eye Research Institute, Bashkir State Medical University, Ufa, Russia
Published: February 2025

Purpose. To study the effect of isotonicity of riboflavin solutions on corneal thickness in an experiment.

Material and methods. The studies were conducted on 9 rabbits (18 eyes) in 3 groups. Photosensitizer solutions developed at the Ufa Research Institute of Eye Diseases were used for instillations on the cornea. In the 1st group, an isotonic solution of riboflavin with hydroxypropyl methylcellulose (HPMC) was used, in the 2nd – isotonic riboflavin, in the 3rd – a hypotonic solution of riboflavin. The studies were performed under general and local anesthesia. Instillation of the studied solutions was carried out for 60 minutes after corneal de-epithelialization: in the 1st group with a frequency of 1 drop per 2 minutes, in the 2nd and 3rd at the rate of 1 drop per 1 min. The corneal thickness of rabbits was determined using optical coherence tomography (Vizante OCT, Germany) every 5 min for 1 hour. The Microsoft Excel 2010 and Statistika 6.0 software packages were used for statistical analysis.

Results. In all groups, after epithelial debriment a slight decrease in corneal thickness was observed by an average of 11±3.9 μm. Isotonic solutions during instillation maintained a stable thickness of the deepithelialized cornea. In group 1, the range of values was from 338 to 366 μm, with an intact corneal thickness of 374±23.1 μm, in group 2 – from 386 to 365 μm, with an intact corneal thickness of 379±28.2 μm. No statistically significant difference was found between the groups. The hypotonic solution (group 3) induced pronounced stromal edema and demonstrated a stable tendency to increase corneal thickness by 13% to 449.6±160.4, compared with its intact state (390.1±36.4 μm).

Conclusion. Using of isotonic (group 1 and 2) and hypotonic (group 3) riboflavin solutions resulted in a short-term slight decrease in corneal thickness against the background of deepithelialization with subsequent stable maintenance of the index in the range ensuring safe surgical intervention. Using the hypoosmotic riboflavin, an increase in corneal thickness was observed up to 13%, which allows this solution to be used in clinical practice in patients with thin corneas (less than 450 μm) under intraoperative control.

Key words: keratoconus, ultraviolet crosslinking of the cornea, photosensitizers, riboflavin, corneal thickness
The nature of the immunological response of the cornea in keratoconus (literature review)
Authors:   Ufa Eye Research Institute, Ufa, Russia, Bikbov M.M. , Shevchuk N.E. ,   Ufa Eye Research Institute, Ufa, Russia, Khalimov A.R. ,   Ufa Eye Research Institute, Ufa, Russia, Gilemzyanova L.I. ,   Ufa Eye Research Institute, Ufa, Russia, Valishin I.D. ,   Ufa Eye Research Institute, Ufa, Russia
Published: February 2025

Keratoconus (КC) is a bilateral and symmetrical disease that leads to progressive thinning of the cornea, followed by the development of abnormal astigmatism and decreased visual acuity. The etiology of КC has not been fully studied, but in recent years it has been associated with inflammation of the eye, which is confirmed by the revealed increase in the local level of pro-inflammatory cytokines and a decrease in anti-inflammatory levels. A change in the production of transforming factors β, an increase in the content of IgE, as well as the induction of apoptic processes in corneal cells were found. Studying the nature of the immunological response of the cornea can help in understanding the mechanisms of pathogenesis of this eye disease and contribute to its more effective treatment.

Key words: keratoconus, cytokines, transforming growth factor, keratocyte apoptosis
Clinical Profile and Outcomes of Three Patients Intrapapillary Hemorrhage with Adjacent Peripapillary Subretinal Hemorrhage: A Case Series
Authors:   Bursa Uludag University School of Medicine, Bursa, Turkey, Kiristioglu M.O. , Gunduz G.U. ,   Bursa Uludag University School of Medicine, Bursa, Turkey, Seyis S. ,   Bursa Uludag University School of Medicine, Bursa, Turkey, Yalcinbayir O. ,   Bursa Uludag University School of Medicine, Bursa, Turkey, Gelisken O. ,   Bursa Private Jimer Hospital, Bursa, Turkey
Published: February 2025

Objective. This case series aims to elucidate the clinical presentation, diagnostic imaging, and outcomes associated with intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage (IHAPSH), highlighting the importance of recognizing this syndrome in young myopic individuals.

Material and methods. We conducted a single-center, retrospective, observational case series including three patients diagnosed with IHAPSH over the past seven years. Diagnostic modalities included cycloplegic refraction, fundus fluorescein angiography and photographs, optical coherence tomography (OCT), ultrasonography, and visual field testing.

Results. The study involved six eyes from three female patients aged 12 to 46. Two exhibited acute and one subacute visual symptoms. Myopic refraction ranged from −1.5 to −6.50 diopters, and initial visual acuity varied from 1.0 to counting fingers at 1 meter. Biomicroscopy showed no significant findings. OCT revealed peripapillary subretinal hemorrhages in two eyes and subretinal hemorrhage at the optic disk in another. Preretinal hemorrhage was also observed. Ultrasonography detected slight elevation at the optic disk head; no drusen were found. All hemorrhages resolved spontaneously without sequelae.

Conclusion. Hemorrhages resolved spontaneously in all cases, affirming IHAPSH’s benign nature. Advanced imaging provided accurate diagnoses, distinguishing IHAPSH from others and emphasizing conservative management. No chronic sequelae were noted, and differential diagnosis prevented unnecessary treatments.

Key words: myopia, optic disk, intrapapillary hemorrhage, peripapillary subretinal hemorrhages
Effectiveness and features of the mechanism of action of the device «Visotronic Mini»   in correcting the adaptive resource of the visual system in students
Authors:   Federal State Budgetary Educational Institution of Higher Education «Izhevsk State Medical Academy» Ministry of Health of Russian Federation, Izhevsk, Russia, Lyalin A.N. , Korepanov A.V. ,   Federal State Budgetary Educational Institution of Higher Education «Izhevsk State Medical Academy» Ministry of Health of Russian Federation, Izhevsk, Russia, Gnezdova R.A. ,   Federal State Budgetary Educational Institution of Higher Education «Izhevsk State Medical Academy» Ministry of Health of Russian Federation, Izhevsk, Russia, Lozhkina A.V. ,   Federal State Budgetary Educational Institution of Higher Education «Izhevsk State Medical Academy» Ministry of Health of Russian Federation, Izhevsk, Russia, Agafonova A.V. ,   Federal State Budgetary Educational Institution of Higher Education «Izhevsk State Medical Academy» Ministry of Health of Russian Federation, Izhevsk, Russia, Zhubanov V.A. ,   Federal State Budgetary Educational Institution of Higher Education «Penza State University» Ministry of Health of Russian Federation, Penza, Russia
Published: February 2025

Purpose. To study the effectiveness and features of the mechanism of action of the device «Visotronic Mini» in correcting the adaptive resource of the visual system in students.

Material and methods. The study involved 30 students (60 eyes) with visual asthenopia, whose average age was 21.6 years. The ophthalmological examination included a questionnaire, visometry, and determination of subjective refraction and binocular stability of visual perception (SVP) to hypermetropic retinal defocus (HRD). Each student underwent a course of optical kinesiotherapy using the device «Visotronic Mini».

Results. After the course of treatment, SVP to GRD increased on average from 380.3 to 479.3% after avergent eye movements, and increased on average from 399 to 503% after divergent eye movements (p<0.001). Moreover, as the need for accommodation increases with the increase of HRD, a regulatory redistribution of muscle tone is noted in the diverging muscles, up to a change in the stress vector, that leads to a temporary change in the geometry of the eyeball.

Conclusion.The use of the device «Visotronic Mini» significantly increases the performance of the ciliary and oculomotor muscles, and also improves the elastic properties of the sclera and the hemodynamics of the eyeball, i.e. factors that form the basis of the adaptive resource of the visual system

Key words: correction of adaptive resource, extraocular divergence accommodation, structural remodeling of the sclera
A clinical case of the use of RPE65 gene replacement therapy in a patient with Leber’s amaurosis
Authors:   Russian Center for Eye and Plastic Surger y, Ufa, Russia, Baranchikova I.V. , Koshelev D.I. ,   Russian Center for Eye and Plastic Surger y, Ufa, Russia
Published: February 2025

Leber congenital amaurosis (LCA) is a hereditary retinal dystrophy that manifests itself from birth or early childhood. The disease is characterized by the absence or sharp depression of visual functions from birth, nystagmus.

The article presents the state and dynamics of visual functions of a patient with LCA type 2, starting from the age of 1 year and 2 months, with treatment in the form of choroidal revascularization and repeated retroscleroplasty of both eyes using the biological drug «Alloplant» before gene replacement therapy (HRT) at the age of 13. Gene replacement therapy after subretinal administration of the drug voretigene neparvovex was carried out at the Eye Microsurgery MNTK (Moscow). The results of measuring visual acuity, electroretinography and recording of visual evoked potentials, as well as characteristics of fixation eye movements are presented. 6 months after HRT, positive dynamics were observed, which was expressed in an increase in visual acuity, improvement in the characteristics of fixation eye movements and parameters of visual evoked potentials for a flash. Issues of diagnosis and management tactics for patients with congenital visual impairments are discussed.

Key words: Leber congenital amaurosis, treatment, dispersed biomaterial «Alloplant», RPE65 gene, gene replacement therapy, voretigene neparvovec, visual acuity, visual evoked potentials, electroretinography, fixation eye movements
ПРЕДПРИНИМАТЕЛЬСКАЯ ДЕЯТЕЛЬНОСТЬ В УНИВЕРСИТЕТЕ: РЕЗУЛЬТАТЫ МОНИТОРИНГА
Authors: Резник Г.А.
Published: February 2025

Необходимым условием ускорения экономического роста и перехода к новому экономическому укладу является подготовка инновационно ориентированных квалифицированных кадров, способных решать важные задачи, стоящие перед обществом. На решение этой задачи нацелен ФЗ № 217 от 02.08.2009, в котором сделан акцент на создание малых и, прежде всего, инновационных предприятий при вузах, тем самым подготовив почву для развития предпринимательских навыков у студентов уже в процессе их обучения. Целью статьи является исследование проблем развития предпринимательства в вузе. Задачи – рассмотрение условий и выявление заинтересованности преподавателей и студентов в открытии собственного предприятия в вузе, выявление причин недостаточно эффективного процесса становления инновационного предпринимательства , разработка рекомендаций по его активизации.

Training of innovation-oriented skilled personnel, able to solve the important problems of the society, is an essential prerequisite for the speedup of economic growth and transition to a new economic order. The research is aimed at studying the problem for promoting the entrepreneurship at a university, revealing the interest of teaching staff and students in setting up their own business at the university, determining the reasons of insufficient process of establishment of innovative entrepreneurship, developing recommendations on its activation. Papers of prominent foreign and Russian scientists, legislative books, methods of statistical and comparative analyses, methods of questionnaire-based survey of teaching staff and university students as well as employers of the Penza region between 2010 and 2018 years (at an interval of two years) were the basis for the study of the problems for the promotion of entrepreneurship in higher school. Results. The problems slowing the process of establishing the small innovation enterprises at the universities were revealed. They are low motivation of students, postgraduate students and teaching staff, complexity in defining the prospective projects and technologies, imperfection of the mechanism of commercialization of technologies as well as the mechanism of financing the innovation activity, unprofessional management of innovation projects and processes, low commercial success of scientific elaborations, etc. It was concluded that Russian universities had a sufficient scientific and scientific engineering potential, including the research facilities, for training the highly-skilled innovation-oriented professionals. One of the priorities is the activation of work on establishment and development of technology transfer centers as the institutional models of integration of fundamental, applied science, education and business that are an important element for establishing the national innovation system.