bluuebunny/crossref_metadata_2025 huggingface dataset:
TOPICALITY OF MONITORING OF INDUSTRIAL FREQUENCY MAGNETIC FIELDS OF 50 HZ IN RESIDENTIAL AND PUBLIC BUILDINGS
Authors: Kalyada Taisiya V. , Plekhanov V. P.
Published: December 2019

The problem of ensuring safety of electric and magnetic fields (EMF) of extremely low frequencies (ELF) is resulted from the development of the first low-frequency generators producing penetrating effect and causing negative biological outcomes. World power resources are doubling every 10 years, and ELF EMF are generated around by such sources. The number of sources on the scale of application, power and design diversity significantly exceeds those generating EMF in other frequency ranges. The population is exposed to 50 Hz ELF at work, in electric transport, in residential and public buildings, in residential areas. ELF EMF was found both to “pollute” the environment, be an environmental health risk factor, and affect negatively the health with potential long-term outcomes. Development of various methods and means of protection against the effect of ELF EMF remains relevant today. Limitation (regulation) of the effect of the factor both in terms of intensity and exposure is the most effective protection. Epidemiological studies to identify the relationship between exposure to ELF magnetic fields (MF) and carcinogenesis are on-going. A task panel group of research experts, established by WHO in 2005, conducted a routine procedure to assess health risks resulting from exposure to ELF MFs and, in particular, cancer and considered them to lack evidence. However, the significance of the data obtained was noted to be reduced due to procedural problems, potential systematic error of assessment. The problem remains unsolved. Research using various types of monitoring: social and hygienic, sanitary and epidemiological, is going on. Spatio-temporal monitoring of 50 Hz ELF MF in enclosed spaces of residential and public buildings, where a variety of equipment, devices, power supply systems, generating different MF levels, is an important area. The population is exposed to these conditions most of the day. Monitoring will allow assessing electromagnetic load at short-term and long-term exposures.
OCCUPATIONAL POLYNEUROPATHY. MODERN OUTLOOK OF THE PROBLEM IN RUSSIA AND ABROAD. REVIEW
Authors: Grebenkov S. V. , Kochetova O. A. , Milutka E. V. , Malkova N. Yu.
Published: December 2019

The article offers an analysis of up-to-date information about the occupational polyneuropathy in domestic and foreign scientific literature. Information search for the occupational polyneuropathy in Russian and foreign scientific literature, analysis of Russian and international approaches to the understanding of this occupational pathology. Review of acceptable scientific Russian and foreign literary sources from the open database PubMed and RSCI (Russian Science Citation Index). In the foreign scientific literature, there are no any mentions about polyneuropathy as an independent occupational pathology. Only items of information about unusual cases in clinical practice are presented. At the same time in Russia, this disease is well known, the criteria of its diagnosis are sufficiently investigated. Russian and foreign researchers point out the specificity of the observed changes in the peripheral nerves of the upper extremities occurring in workers engaged in heavy physical labor. Currently, in Russia, this pathology is diagnosed quite often. Conclusion. Professional polyneuropathy of upper extremities caused by physical overload is a common occupational disease. In Russia it has been studied for a long time, it is often diagnosed, but it is practically unknown abroad. An interdisciplinary approach is necessary for the early detection, treatment of the disease and the removal of workers from contact with physical overload. The successful development of modern occupational pathology depends on the exchange of experience and collected information.
EXPERIMENTAL HYGIENIC ESTIMATION OF CALCIUM AND MAGNESIUM CONCENTRATIONS IN DRINKING WATER, AND ITS HARDNESS
Authors: Trofimovich E. M. , Nedovesova S. A. , Aizman Roman I.
Published: December 2019

Introduction. The lack of hygienic norms for Mg2+ and Ca2+ in drinking water and the wide ranges of acceptable hygienic norms (AHN) of these cations in water packaged in containers determine the relevance of experimental studies on the substantiation of AHN of Mg2+, Ca2+ and the hardness of drinking water with a centralized water supply to the population. Material and methods. Chronic experiments were performed on 5 groups of adult Wistar rats (n = 50): control animals received drinking water (Ca2+ 20.0; Mg2+ 6.0 mg / dm3, hardness 1.5-1.8 mEq/dm3); four other groups received model drinking water with different contents of Ca2+ (50, 80, 100 and 140 mg/dm3) and Mg2+ (20, 40, 55 and 85 mg/dm3) by adding CaCl2 or MgSO4 salts to the control water. The effect of these drinking water samples on kidney function, ion osmotic blood parameters, plasma metabolites of lipid and protein metabolism, as well as the concentration of thyroid hormones (T3 and T4) and cortisol were studied. Results. Prolonged action of increased concentrations of Ca2+ and Mg2+ on the organism was established to cause alterations in fat metabolism, the adaptive activation of osmoregulatory and ion regulatory kidney functions, increasing the concentration of thyroid hormones and a decrease of cortisol titer in plasma. Magnesium led to more pronounced changes in water-salt metabolism, and at a concentration of 85.0 mg/dm3 (7.0 mg-Eq/dm3) - to depletion of secretion of the described hormones. Conclusion. Based on the obtained results, individual ranges for AHN of calcium and magnesium concentrations in water were recommended. The upper limit of AHN of drinking water total hardness is of 7.0 mg-Eq/dm3 at the joint presence of Ca2+and Mg2+. The rule of hygienic qualitative and quantitative estimation of calcium and magnesium types of drinking water hardness is formulated.
THE SEVERITY OF ENDOGENOUS INTOXICATION AND OXIDATIVE STRESS IN THE BLOOD OF WORKERS IN CONTACT WITH GLYCINE DERIVATIVES
Authors: Miroshnikova Darya I. , Kiryushin V. A. , Prokhorov N. I. , Fomina M. A. , Motalova T. V. , Bolshakov A. M.
Published: December 2019

Introduction. Currently, the search for markers of the health status of workers in agro-industrial complexes in contact with pesticides continues. The aim of this study was the assessment of the effect of glyphosate isopropylamine salt on the health of workers in agroindustrial complexes of the Ryazan region according to the severity of endogenous intoxication and oxidative stress in the body. Materials and Methods. Plasma and erythrocytes of peripheral blood of workers were the clinical material for the study. Blood was taken in 87 workers contacted with glyphosate-containing pesticides. As a control group, 20 clinically healthy individuals of the same age category who did not have contact with the pesticides were selected to be studied. The severity of endogenous intoxication was determined by the level of substances of low and medium molecular weight in the plasma and red blood cells. The severity of oxidative stress was determined by the content of the products of oxidative modification of proteins by the method of R.L. Levine modified by E.E. Dubinina. Results. Statistically significant changes in the severity of endogenous intoxication in the blood plasma and erythrocytes of the study groups and the control group of individuals among machine operators and workers who come into contact with pesticides to a lesser extent were obtained. A statistically significant increase in the level of carbonyl derivatives compared with the control among machine operators who have greater contact with glyphosate-containing pesticides according to the time sheets has been revealed. The level of secondary carbonyl derivatives in machine operators was higher than that of warehouse workers and was statistically significant. Conclusion. A statistically significant increase in the level of secondary carbonyl derivatives among machine operators as compared with other workers is a late marker of oxidative stress, which indicates to a depletion of the reserve forces of the body. This may be due to longer contact with pesticides based on glyphosate machine operators as compared to other workers in the agro-industrial complexes.
Neer Type-II Distal Clavicle Fractures
Authors: Fox Henry M. , Ramsey Duncan C. , Thompson Austin R. , Hoekstra Chris J. , Mirarchi Adam J. , Nazir Omar F.
Published: December 2019

Background:

Neer type-II distal clavicle fractures are unstable and are generally appropriately managed with operative fixation. Fixation options include locking plates, hook plates, and suture button devices. No consensus on optimal technique exists.

Methods:

A decision tree model was created describing fixation of Neer type-II fractures using hook plates, locking plates, or suture buttons. Outcomes included uneventful healing, symptomatic implant removal, deep infection requiring debridement, and nonunion requiring revision. Weighted averages derived from a systematic review were used for probabilities. Cost-effectiveness was evaluated by calculating incremental cost-effectiveness ratios (ICERs). The ICER is defined as the ratio of the difference in cost and difference in effectiveness of each strategy, and is measured in cost per quality-adjusted life year (QALY). The model was evaluated using thresholds of $50,000/QALY and $100,000/QALY. Sensitivity analysis was performed on all outcome probabilities for each fixation strategy to assess cost-effectiveness across a range of values.

Results:

Forty-three papers met final inclusion criteria. Using suture buttons as the reference case in the health-care cost model, suture button repair was dominant (both less expensive and clinically superior). Hook plates cost substantially more ($5,360.52) compared with suture buttons and locking plates ($3,713.50 and $4,007.44, respectively). Suture buttons and locking plates yielded similar clinical outcomes (0.92 and 0.91 QALY, respectively). Suture button dominance persisted in the societal perspective model. Sensitivity analysis on outcome probabilities showed that locking plates became the most cost-effective strategy if the revision rate after their use was lowered to 2.2%, from the overall average in the sources of >19%. No other changes in outcome probabilities for any of the 3 techniques allowed suture buttons to be surpassed as the most cost-effective.

Conclusions:

The cost-effectiveness of suture buttons is driven by low revision rates and high uneventful healing rates. Similar QALY values for locking plate and suture button fixation were observed, which is consistent with existing literature that has failed to identify either as the clinically superior technique. Cost-effectiveness should fit prominently into the decision-making rubric for these injuries.

Level of Evidence:

Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Autologous Iliac Bone Graft Compared with Biphasic Hydroxyapatite and Calcium Sulfate Cement for the Treatment of Bone Defects in Tibial Plateau Fractures
Authors: Hofmann Alexander , Gorbulev Stanislav , Guehring Thorsten , Schulz Arndt Peter , Schupfner Rupert , Raschke Michael , Huber-Wagner Stefan , Rommens Pol Maria ,   on behalf of the CERTiFy Study Group
Published: December 2019

Background:

Bone-graft substitutes are commonly used for the augmentation of traumatic bone defects in tibial plateau fractures. However, their clinical performance compared with that of autologous bone-grafting, the gold standard in bone defect reconstruction, still remains under debate. This study investigates the differences in quality of life, pain, and radiographic outcomes in the treatment of tibial plateau fracture-associated bone defects with either autologous bone grafts or a bioresorbable hydroxyapatite and calcium sulfate cement (CERAMENT BONE VOID FILLER [CBVF]; BONESUPPORT).

Methods:

In this study, 135 patients with acute depression and split-depression fractures of the proximal part of the tibia (OTA/AO types 41-B2 and 41-B3) were enrolled in a prospective, controlled, randomized, multicenter trial including 20 hospitals in Germany. Patients were randomized to receive either autologous iliac bone graft or CBVF for reconstruction of the bone defect. The primary outcome measures were the Short Form (SF)-12 version 2 Physical Component Summary (PCS) score at week 26 (the study was designed to show noninferiority of the CBVF with regard to the PCS with a prespecified margin of −5 points) and the pain level at 26 weeks postoperatively measured by a visual analog scale (VAS). The secondary outcomes were the SF-12 version 2 Mental Component Summary (MCS) and SF-12 PCS scores at weeks 1, 6, and 12 and bone-healing on radiographs.

Results:

Age, sex, fixation methods, and fracture pattern were comparable in both groups. There were no significant differences (p > 0.05) in the SF-12 PCS or VAS scores at postoperative week 26. There was a significant reduction of blood loss (p = 0.007) and pain levels (p = 0.008) at postoperative day 1 in the CBVF group. The rates of fracture-healing, defect remodeling, and articular subsidence were not significantly different (p > 0.05) in both groups.

Conclusions:

Bioresorbable CBVF was noninferior to autologous bone graft with regard to both patient-reported and radiographic outcomes in tibial plateau fractures of OTA/AO types 41-B2 and 41-B3.

Level of Evidence:

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
The Analysis of Available Data on Energy Efficiency of Electric Vehicles to be Used for Eco-Driving Project Development
Authors: Maljković M. , Stamenković D. , Blagojević I. , Popović V.
Published: December 2019

The goal of this paper is to analyse the collected data on energy efficiency of electric vehicles from researches done by other authors and also to summarise all the factors affecting it. The majority of data available are obtained through simulations – therefore the emphasis in this paper will be placed on experimentally acquired data. The results of the analysis will be used for the planned e-bus eco-driving project for the purpose of Belgrade’s public transportation system. Currently there are only 5 (ultracapacitor type) e-buses operating in Belgrade city public transport, which makes only 0.2 % of all vehicles in rolling stock (making 16 % together with other electric-powered vehicles – trams and trolleybuses), but there are plans to acquire new 80 electric buses. With the rise of the number of electric vehicles, appropriate training of drivers is gaining more and more importance, and the results of the presented analysis make the basis for such training. This will hopefully increase the range of the buses used and help save the energy spent by public transportation, thus giving a little contribution to global fight for cleaner planet.
Structure and ultrastructure of neurospheres spontaneously generated in culture from sheep ovarian cortical cells.
Authors: Salvador Concepción Rojo , Sánchez-Maldonado Belén , Galicia María de Lourdes , González-Gil Alfredo , González Rosa Ana Picazo
Published: December 2019

Background: Neurospheres derived from adult stem cells of non-neural tissues represent a promising source of neural stem cells (NSCs) and neural progenitor cells (NPCs) for autologous cell therapy in neurological diseases. Analyzing the fine structure of neurospheres can provide pivotal information regarding the phenotype of spheroid-integrating cells, being useful for cell characterization during differentiation, and oncogenic transformation. Neurospheres can be generated by culturing ovarian cortical cells under particular conditions. In order to assess the reliability of use of these spheroids in regenerative medicine, developmental biology, and to state whether they share morphological features with central nervous system (CNS) derived neurospheres, they were analyzed by light and transmission electron microscopy. Sheep ovarian cortical cells were cultured in serum-free medium for 21 days to generate neurospheres. On days 10, 15 and 21 of culture, expression of pluripotency (Nanog, Oct4, Sox2), and NSC/NPC (nestin, Pax6, P75NTR) transcripts by qRT-PCR, immunolocalization of NSC/NPC antigens (nestin, Pax6, P75NTR), structure, and ultrastructure, were analyzed in spheroids. Results: Spheroids expressed transcripts and antigens of pluripotency, and NSC/NPC. Structural analyses revealed that cells were arranged in a peripheral sheet cover comprised by a few layers of spindle-shaped cells exhibiting frequent mitoses, and large round cells; and an inner core, with intermediate-sized cells showing frequent events of apoptosis and necrosis. Ultrastructural analyses showed that in the inner core, most cells were electron dense (dark), showing frequent apoptotic and degenerative events; the outer epithelium-like sheet, was formed by low electron dense cells (light flat cells; LFCs) showing signs of intense metabolic activity, abundant cytoplasmic organelles, phagosomes, lysosome-like structures, apical microvilli, and filament bundles of cytoskeleton elements, indicating that LFCs play a role in extracellular exchanges. Apical-basal polarization of LFCs evidenced by frequent intercellular contacts, like adherens junctions and cytoplasmic interdigitations, was lost in some cells whose contacts with neighboring cells were loose intedigitations and expanded cytoplasmic processes. This might anticipate disengaging/aggregating of light protruding cells (LPCs) from/to the neurosphere, as consistently observed in cultures by inverted microscopy. Conclusions: Neurospheres spontaneously generated from ovarian cortical cells in culture, share most structural and ultrastructural characteristics of neurospheres derived from the CNS.
Effect of parental depression on asthmatic children’s problem behavior and academic performance: using actor and partner interdependence model of parental variables
Authors: Kim Jeong Min , Lee Hanna , Han jeongwon
Published: December 2019

Background The health issues of children with asthma is emerging to be a social problem because in many cases it is a disease that requires repetitive and long-term treatment, and the financial burden of parents raising children with asthma is relatively greater than parents raising normal children. It is necessary for health care providers to approach the mental health of parents in addition to managing the health of asthmatic children so that asthmatic children recover, smoothly adjust to school life like other normal children. This study attempts to determine the factors on the problem behavior and academic performance of the children with asthma.Methods The data of 236 pairs of children and parents from the 10th Panel Study on Korean Children were used and analysis was performed using SPSS 20.0 and AMOS 20.0.Results Parental depression had actor and partner effects on marital conflict, and marital conflict perceived by the father had actor and partner effects on parent-child interactions, while marital conflict perceived by the mother had actor effect on parent-child interactions. Parent-child interaction perceived by the father was found to affect the problem behavior of children, and parent-child interaction perceived by the mother was seen to affect the problem behavior of children. The problem behavior of children affects academic performance.Discussion This study is significant since it prepares basic data for improving the academic performance of children with asthma. We suggest research that longitudinally confirms the influence using variables presented in this study is necessary.
Evaluation of Infection, Prevention and Control Program in Goromonzi District, Zimbabwe, 2018: A process outcome evaluation
Authors: Emmanuel Govha , Tirivanhu Zizhou Simukai , Gerald Shambira , Notion Gombe Tafara , Juru Tsitsi , Chiwanda Simbarashe , Mufuta Tshimanga
Published: December 2019

Background A healthcare-associated infection (HAI) is defined as an infection originating in the environment of a health facility that was not present or incubating at the time of patient admission. HAIs can be prevented through infection, prevention and control (IPC) measures. No hazard identification and risk assessment IPC rounds and monthly meetings were conducted in Goromonzi district since 1st of January to 30th of June 2018. No trainings nor orientation for the new employees was conducted. We therefore evaluated Goromonzi District IPC program. Methods A process-outcome evaluation using the logic model was conducted in Goromonzi district’s 15 health facilities. Checklists, interviewer administered questionnaires and key informant guides were used to collect data on availability of inputs, knowledge of health workers, processes performed, outputs and outcomes achieved. Data were entered into Epi Info 7TM, which was used to generate frequencies and proportions. Qualitative data from checklists and key informants interviews was sorted manually into themes and analysed. Results All 15 health facilities had adequate stocks of HIV test kits and PEP kits. Adequate bins and detergents were found in only 3/15 (20%) of health facilities. All facilities failed to hold a single IPC meeting and none had specific budget for IPC in 2018. No IPC mentorship activities were carried out in the district. Only 7/13 (54%) health workers who had needle pricks received PEP with 2/7 (29%) of them finishing the course. No health facility had a functional HAI surveillance system. The overall knowledge rating was fair. Conclusion The IPC program inputs in Goromonzi district were inadequate hence its failure to achieve the intended outputs and outcomes. Inadequate knowledge, unavailability of health worker training plans, specific budgets and absence of IPC committees reflected non prioritisation of the program.
Psychiatrists’ Attitude to the Psychiatrist’s Style of Dressing and Addressing: A Cross -Sectional Study
Authors: Semnani Yousef , Ardalan Arash , Shahpouri Hamid Reza , bastami fatemeh
Published: December 2019

Background The relationship between physician and patient is important topic in medical practice. How a physician dresses and addresses the patients are key factors that contribute to developing a rapport. This study aimed to investigate the psychiatrist's perspectives in order to facilitate an effective communication with patients.Methods This descriptive-analytic study was done on psychiatrists and psychiatric residents through a non-selective and non-randomized sampling method. Data were collected based on a questionnaire. Variables were such as age, sex, duration of practice as a psychiatrist, priority for male psychiatrist dress preference, priority for female psychiatrist dress preferences, priority for choosing a doctor from a gender perspective, priority for being addressed by patients, using the word of the gentleman or lady to address the patients, and the type of verbs and pronouns used by the psychiatrist and the patient during the interview in terms of the total number of verbs and pronouns. Subsequently, eight photographs of male and female physician’s coverage according to the in Iranian culture were shown to the participants and they were asked to choose one.Results A total of 77 psychiatrists participated in this study, of which 45 (58.4%) were male and 32 (41.6%) were female. In case of male psychiatrist’s coverage, 56 (72.7%) participants preferred suits; whereas in case of female psychiatrist’s coverages, 25 (32.5%) participants chose colored mantos and scarves, 22 (28.6%) selected black manteos and head dresses. Sixty three (81.8%) patients believed that the gender of the physician was not important in determining the treating physician. According to the type of addressing the psychiatrist by patients, 71 (92.2%) participants preferred to call the doctor's name followed by surname and 60 (77.9%) psychiatrists wanted patients to use the word "Mr. or Ms.” prior their names. Sixty three (81.8%) psychiatrists stated that it was better to use plural pronouns and verbs in interviewing patients, and 67 (87%) preferred their patients to use plural verbs to address them.Conclusions Psychiatrists’ appearance and the accuracy of the patient-referring type, based on what the physicians believe, along with the characteristics of the patients’ perspectives, help improving physician-patient relationship.
MicroRNA-4651 targets bromodomain-containing protein 4 to inhibit non-small cell lung cancer cell growth
Authors: Zheng Jiangnan , Dong Lingyun , Zhang Yan , Cai Shang , Hu Xiaoyun , Chen Min-bin , Zhu Ye-han
Published: December 2019

Background: Bromodomain-containing protein 4 (BRD4) overexpression in non-small cell lung cancer (NSCLC) is important for cancer cell progression. The aim of the present study is to silence BRD4 through expression of its targeted microRNAs in NSCLC cells. Methods: Expression of BRD4 and its targeting miRNA, microRNA-4651 (miR-4651), was tested by qPCR and Western blotting assays. Genetic strategies were utilized to exogenously alter miR-4651 expression. NSCLC cell growth, proliferation and migration were tested. Results: miR-4651 selectively targets and negatively regulates BRD4 in A549 and primary human NSCLC cells. The Ago-2 immunoprecipitation experiments further confirmed that miR-4651 directly binds to BRD4 mRNA. Significantly, in A549 cells and primary NSCLC cells ectopic overexpression of miR-4651 downregulated BRD4’s 3-UTR activity and its expression, both were however elevated with miR-4651 inhibition. Functional studies demonstrated that NSCLC cell growth, proliferation and migration were significantly inhibited with miR-4651 overexpression, but enhanced with miR-4651 inhibition. BRD4 re-expression, by an 3’-UTR mutant BRD4, reversed miR-4651 overexpression-induced inhibitions on A549 cells. Additionally, miR-4651 overexpression or inhibition failed to affect the functions of BRD4-KO A549 cells. In vivo, miR-4651-overexpressed A549 xenografts grew significantly slower than control A549 xenografts in severe combined immunodeficient mice. At last we show that miR-4651 is downregulated in human NSCLC tissues, correlating with BRD4 elevation. Conclusions: miR-4651 targets BRD4 to inhibit NSCLC cell growth in vitro and in vivo.
Impact of Intestinal Parasites on Microbiota and Metagenomic Influences on Gene Encoding Cobalamin Pathway
Authors: Mejia Rojelio , Damania Ashish , Jeun Rebecca , Bryan Patricia , Vargas Paola , Juarez Marisa , Cajal Pamela , Nasser Julio , Krolewiecki Alejandro , Lefoulon Emilie , Long Courtney , Drake Evan , Ciminio Ruben , Slatko Barton
Published: December 2019

Background: Approximately 30% of children worldwide are infected with gastrointestinal parasites. Depending on the species, parasites can disrupt intestinal bacterial flora affecting nutritional status. We implemented a multi-parallel quantitative real-time PCR and whole-genome sequencing analysis for bacterial microbiota and Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Trichuris trichiura, Cryptosporidium species, Entamoeba histolytica, and Giardia lamblia. Stool samples were collected from 37 asymptomatic children from rural Argentina. We focused this study on Giardia screening. Separate analyses were done for uninfected, Giardia only, Giardia/helminth coinfections, and helminth only groups.Results: For Giardia only infected children, DNA sequencing data showed a decrease in microbiota biodiversity compared to those uninfected that correlated with increasing Giardia burden. Clustering was statistically significant using Shannon alpha diversity. A non-significant increase in diversity was observed for helminth only infections with a compensatory decrease in Giardia/helminth coinfections. In Giardia only infections, microbiome taxonomy shifted from Firmicutes towards increasing proportions of Prevotella, with the degree of shift related to the intensity of infection compared to uninfected. An abundance of Prevotella bacteria was decreased in the helminths only group but increased for Giardia/helminth coinfections. Metagenomic analysis of the bacterial microbiota showed that the proportion of non-vitamin B12 producing bacteria (Prevotella) was higher in the Giardia group. Total cobalamin synthesis was decreased in the Giardia-infected only group compared to the control and helminth-infected group. Conclusion: Our data provide evidence for an effect of parasitic infections allowing permissive growth of anaerobic bacteria such as Prevotella, suggesting an altered capacity of vitamin B12 biosynthesis and potential impact on growth and development in children.
Testing the linkages of Arab stock markets: a multivariate GARCH approach
Authors: Shahateet Mohammed , Shrydeh Najib , Mohammad Suleiman
Published: December 2019

The authors undertook to examine 720 monthly observations of activity in 15 Arab stock markets over four years (from 2014 to 2017) to identify the dynamic linkages among those markets. To achieve this, several forms of the Generalized Auto-Regressive Conditional Heteroskedasticity (GARCH) model were utilized. Both panel and individual stationarity, in addition to cointegration tests, were employed to highlight the interaction between these markets. The results suggest that Arab stock markets have weak linkages with the exception of those of the Gulf Cooperation Council (GCC). The authors also find out that the TARCH, EGARCH, PARCH, and Component GARCH (1,1) models are suitable in terms of passing the econometric analysis tests. Nevertheless, they conclude that the EGARCH model is the most appropriate for capturing the cross-market dynamic linkages, thereby outperforming the other GARCH specifications under study. The empirical findings bear special implications for economic literature regarding linkages of stock markets in the Arab world.
UMA PROPOSTA DE REGISTRO DE IMAGEM TÉRMICA PARA POSSÍVEL UTILIZAÇÃO NA DETECÇÃO DE FALHAS EM EQUIPAMENTOS ELÉTRICOS
Authors: Dos Santos Aparecido Juneo , Vieira Antônio Wilson , Silveira Vasconcelos D'Angelo Marcos Flávio , Pereira Neirismar Antunes
Published: December 2019

O presente trabalho propõe uma metodologia baseada em termografia para possível detecção de falhas em equipamentos elétricos. Para isso é utilizada uma câmera da marca FLIR Systems modelo E6 que disponibiliza tanto a imagem térmica quanto a imagem RGB da mesma cena. As imagens térmicas capturadas em diferentes instantes de tempo são alinhadas a partir de uma transformação obtida pelo registro das imagens RGB correspondentes, que é a principal contribuição do trabalho. Com as imagens térmicas alinhadas, foi criado um índice temporal que é utilizado para detectar a possível ocorrência de uma falha em um equipamento elétrico. O acompanhamento permite analisar a evolução da temperatura e assim com uma variação de temperatura encontrada, o detector de falha sinaliza essa mudança de temperatura que pode indicar uma falha de funcionamento
AVALIAÇÃO DE POTENCIAL EÓLICO E SOLAR COM CORRELAÇÕES DE LONGO ALCANCE EM SÉRIES TEMPORAIS EM SALVADOR
Authors: Santos José Vicente Cardoso , De Santana Acioli Palmira Maria , Rosales Aylas Georgynio Yossimar , Marinho Chrislaine do Bomfim , Moreira Davidson Martins , Moret Marcelo Albano Albano , Nascimento Erick Giovani Sperandio
Published: December 2019

Este trabalho mostra a existência de correlações de longo alcance das séries históricas e temporais de velocidade do vento e radiação solar na cidade de Salvador (Bahia) provenientes de dados medidos em estações meteorológicas, além de simulações com o modelo de mesoescala WRF (Weather Research and Forecasting), através do método DFA (Detrended Fluctuation Analysis). Resultados preliminares indicam que as séries de dados locais são caracterizadas com persistência na velocidade do vento e radiação solar de forma satisfatória para a geração de energia, o que indica viabilidade da participação destas respectivas matrizes na matriz energética local.
MÉTODO DE ANÁLISE POR ENVOLTÓRIA DE DADOS PARA AVALIAÇÃO DE UM NICHO DE TELEVISORES NO MERCADO NACIONAL
Authors: Matos Mariane Rangel de , Da Hora Henrique Rego Monteiro , Ferreira Cristine Nunes
Published: December 2019

No período de 2011 à 2016 houve um aumento de 17,2% das unidades de habitação destinadas ao setor de turismo necessitando de uma modernização constante nos serviços oferecidos. Desta forma, é recomendado a aquisição de aparelhos de televisão que possuam tecnologia no mínimo DTV. Aplicou-se o modelo de análise envoltória de dados, Data Envelopment Analysis (DEA), para avaliar a eficiência na aquisição de aparelhos de televisão. Foram avaliados dezesseis aparelhos de várias marcas que estão disponíveis no mercado nacional. As variáveis consideradas foram a potência e o preço como inputs e o tamanho da tela como output. Dentre os modelos DEA, optou-se pelos modelos CCR e BCC. Um dos resultados alcançados com esse método foi a possibilidade de distinguir os aparelhos eficientes dos ineficientes, encontrando dois tipos de aparelhos eficientes auxiliando na aquisição das mercadorias. Outro resultado interessante foi a possibilidade de otimizar o mercado buscando meios para mudança nos produtos oferecidos visando atender a demandas como menores preços e menor consumo de energia. Essa otimização foi feita usando o método BCC onde foi encontrado quatro aparelhos eficientes. O trabalho mostra a viabilidade da aplicação do DEA para ajudar na tomada de decisão e promover a melhoria nos produtos ofertados.
AVALIANDO DIFERENTES IMPLEMENTAÇÕES DO DESCRITOR DE COR DOMINANTE
Authors: Novaes João Victor de Oliveira , Benedito Caio César da Silva , Santos Lúcio Fernandes Dutra
Published: December 2019

Neste artigo, é apresentado uma proposta de plataforma de teste para implementações dequatro versões do extrator de característica descritor de cor dominante definido pelo padrão MPEG-7. A plataforma simula a tarefa de recuperação de imagem baseada em conteúdo e avalia tanto a qualidade das respostas fornecidas quanto o tempo médio de execução dos algoritmos. Foram conduzidos experimentos utilizando três conjuntos de dados reais e os resultados experimentais demonstram que a escolha da implementação do extrator de característica impactam tanto na etapa de extração dos vetores de características quanto no tempo de consulta.
UMA ABORDAGEM COMPARATIVA ENTRE MÉTODOS DE CATEGORIZAÇÃO E CLASSIFICAÇÃO APLICADOS À SATISFAÇÃO DE CLIENTES COM SERVIÇOS BANCÁRIOS
Authors: Leonardo Fabiane Araujo , Morais Alline Sardinha Cordeiro , Da Hora Henrique Rego Monteiro
Published: December 2019

Conhecer as necessidades dos clientes tornou-se um fator competitivo para as organizações. Nas instituições financeiras, tão importante quanto prospectar novos clientes, é manter os já existentes, por isso, é fundamental que os gestores adotem em seu planejamento estratégico, indicadores que consigam mensurar o fator de qualidade. Este trabalho propõe o levantamento de dados através de um questionário e a análise deles à luz de dois métodos, o IPA e o ELECTRE TRI. Os resultados encontrados demonstraram que, os ambos podem ser utilizados para avaliar a satisfação do cliente. Contudo, quando utilizados juntos, apresentam perspectivas diferentes que, combinadas, resultarão em estratégias mais assertivas para garantir que o cliente tenha satisfação com o serviço contratado.
MODELAGEM MULTICRITÉRIO DA COPA DO MUNDO DE 2018 UTILIZANDO MÉTODO PROMÉTHÉE II
Authors: De Campos Daniel Nocera , Freire Alisson de A. , Da Hora Henrique Rego Monteiro , Ferreira Cristine Nunes
Published: December 2019

O futebol é um esporte que tem grande impacto social e econômico no âmbito mundial. Clubes e seleções são cada vez mais vistos como um negócio rentável, e obrigatoriamente a eficiência de times tem cada vez mais papel importante em sua sobrevivência. Até a Copa de 2018 a FIFA utilizava um método de cálculo de ordenação que tinha características compensatórias, onde bons desempenhos em alguns critérios suprem a deficiência em outros. Este trabalho se propõe em dar um tratamento não compensatório e multicritério para ordenação das seleções participantes da Copa do Mundo de 2018 adotando o método PROMÉTHÉE II. Os resultados apontam dispersões com relação a classificação final da Copa 2018 e o rank FIFA de clubes. A ordenação encontrada no trabalho é considerada mais realista, pois incorpora elementos de imprecisão e não-compensação..
Methods for the Determination of the Purity of Exosomes
Authors: Kluszczyńska Katarzyna , Czernek Liliana , Cypryk Wojciech , Pęczek Łukasz , Düchler Markus
Published: December 2019

Background:

Exosomes open exciting new opportunities for advanced drug transport and targeted release. Furthermore, exosomes may be used for vaccination, immunosuppression or wound healing. To fully utilize their potential as drug carriers or immune-modulatory agents, the optimal purity of exosome preparations is of crucial importance.

Methods:

Articles describing the isolation and purification of exosomes were retrieved from the PubMed database.

Results:

Exosomes are often separated from biological fluids containing high concentrations of proteins, lipids and other molecules that keep vesicle purification challenging. A great number of purification protocols have been published, however, their outcome is difficult to compare because the assessment of purity has not been standardized. In this review, we first give an overview of the generation and composition of exosomes, as well as their multifaceted biological functions that stimulated various medical applications. Finally, we describe various methods that have been used to purify small vesicles and to assess the purity of exosome preparations and critically compare the quality of these evaluation protocols.

Conclusion:

Combinations of various techniques have to be applied to reach the required purity and quality control of exosome preparations.
Association between Single-nucleotide Polymorphisms of RXRG and Genetic Susceptibility to Type 2 Diabetes in South China
Authors: Yu Haibing , Wang Shu , Hu Wei , Xu Lin , Ding Yuanlin , Kong Danli , Pan Haiyan
Published: December 2019

Objective:

To investigate the relationship between genetic polymorphisms of
RXRG rs1467664, rs3753898 and the genetic susceptibility of type 2 diabetes in the
Chinese Han population from South China.

Methods:

In our case-control study, single-nucleotide polymorphisms (SNPs) rs1467664
and rs3753898 were genotyped by SNPscanTM kit in 1092 patients with T2D as cases and
1092 normal persons as controls. The distributions of genotype and allele frequencies in
two groups were analyzed by the SPSS 20.0 software.

Results:

The distribution of genotypes and alleles of RXRG rs3753898 was statistically
significant between the two groups, but there was no significant difference in the
distribution of genotypes and alleles of the rs1467664. Before and after the adjustment of
age, sex and BMI, rs3753898 in the two groups had statistical significance under the
additive, dominant and recessive models (P<0.05), but no statistical differences were
found under the overdominance and co-dominant genetic models (P>0.05). There was no
significant difference in the genetic models of rs1467664 between the two groups
(P>0.05). The haplotype, which consists of rs1467664 allele T and rs3753898 allele A was
a high-risk factor for T2D, OR=1.27, 95% CI (1.09-1.47), Padj=0.002.

Conclusion:

Our results showed that the single nucleotide polymorphism of RXRG
rs3753898 may be related to genetic susceptibility of type 2 diabetes. The haplotype
consisting of the allele T of rs1467664 and the allele A of rs3753898 is a risk factor for type
2 diabetes, suggesting that the genetic variation of RXRG gene may be the genetic cause
of diabetes mellitus in the Chinese Han population.
Analysis of impact factors on creative manufacture labor absorption in tenun endek creative industry
Authors: Suantara I Made , Dewi Made Henny Urmila
Published: December 2019

The thriving creative industry in Klungkung Regency is the Tenun Endek industry. This study aims to analyze: 1) the direct effect of capital, wages, investment and technology on the production in the Tenun Endek handicraft industry in Klungkung Regency, 2) the direct effect of capital, wages, investment, technology, and the production on labor in the Tenun Endek handicraft industry in Klungkung Regency, 3) the indirect effect of capital, wages, investment, technology on labor absorption through the production in the Tenun Endek handicraft industry in Klungkung Regency. The analytical tool used is descriptive analysis, path analysis. The results showed that capital, wages, investment, and technology had a significant positive effect on the number of Tenun Endek handicraft industry production in Klungkung Regency. Capital, wages, technology, total production have a significant positive effect on labor. The investment has a significant negative effect on the labor of endek woven handicraft industry workers in Klungkung Regency. Capital, wages and technology have a significant positive effect on labor through total production, while investment has a significant negative effect on labor through total production.
Predicting business performance through leadership style and job motivation
Authors: Mantera P. Ida Bagus Semara , Riana I Gede
Published: December 2019

Leadership is a character, habit, and personality that distinguishes a person in interacting with others. Leadership is also considered a norm of behavior that is used when trying to influence the behavior of others. Leadership is not always associated with behavior in the right situation, but also how other people are involved so they want to think about realizing the organization's vision and mission. This study aims to analyze the influence of leadership style on Village Credit Institution (LPD) motivation and performance. The study used a questionnaire distributed to 115 employee respondents in 32 LPD in the city of Denpasar. The results of distributing questionnaires received 100 completed questionnaires and were declared valid. Furthermore, the data collected has been analyzed using descriptive analysis and inferential analysis using Smart PLS. The analysis showed that the leadership style had a significant effect on job motivation and LPD performance. Job motivation has a significant effect on LPD performance. While the indirect influence of leadership style on LPD performance shows the important role of job motivation in improving LPD performance.
Geographic information system for manabí sustainable development
Authors: Bazurto José Javier Bravo , Falcones Victor Alfonso Martínez , Gámez María Rodríguez , Arvelo María Giuseppina Vanga
Published: December 2019

One of the barriers that are recognized based on the sustainable development of the territories is related to the lack of information. This research aims to design a Geographic Information System for information management of Renewable Energy Sources (FRE), which improve its quality, energy efficiency and enhance the diversification of generation sources in the province of Manabí, Ecuador. Following a documentary and applied research, the proposed system will be shown through a GeoWeb where it is intended to replace the manual way of updating information regarding FRE, conventional energy sources and renewable potentials by an automated system, with greater consistency and facilitating the handling and access to information quickly and safely; In addition to making viable the decision-making and the conception of strategies, with an integrating vision that allows to move from the current energy model that is based on fossil fuels to an energy-sustainable one.
Performance of stock portfolio based on contrarian strategy in indonesia stock exchange
Authors: Pratama I Gede Wira , Rahyuda Henny
Published: December 2019

This study aims to determine the differences in the performance of high abnormal stock portfolio during the test period compared with the performance of the stock portfolio in the formation period, the difference in the performance of the low abnormal return of the test period compared to the portfolio performance of the stock formation period, as well as the difference in the performance of the high abnormal return stock portfolio (winner) compared with a low abnormal return (loser) test period. The sample consists of shares included in the Kompas 100 index which are listed on the Indonesia Stock Exchange. The sampling method used in this study is a tiered sampling method that is analyzed by means of the two different test. The results showed that within a period of 12 months, there was a positive difference of 10.59% in the loser stock portfolio against the winner stock portfolio in the next period. Stocks that initially had low abnormal returns (losers) experienced a greater return reversal than the winner stock portfolio return in the next period, indicating a market anomaly associated with the overreaction hypothesis.
Market reaction to the rights issue announcement on the Indonesia stock exchange
Authors: Dewi Ni Putu Linsia , Candraningrat Ica Rika
Published: December 2019

Rights issue or the issuance of pre-emptive rights are the rights granted by an issuer company made to its existing shareholders to buy new shares issued within a predetermined period of time. This study aims to empirically explain the differences in abnormal returns before and after the announcement of the rights issue and to determine the form of capital market efficiency in Indonesia. Data are collected from 27 listed companies in the Indonesia Stock Exchange (IDX) that conducted a rights issue in 2014-2018. The data analysis technique used is the Kolmogorov-Smirnov Normality Test and the Parametric Statistical Test with a paired sample t-test. Based on the results of hypothesis testing not found differences in abnormal returns both before and after the announcement date indicating the market does not react to the right issue event. The results of statistical tests show a downward trend of abnormal return which is proxied in the Cumulative Abnormal Return (CAR), implying a market tends to react negatively to the announcement of the rights issue. Rights issue information causes a new equilibrium price adjustment in the market, thus making the form of efficiency of the Indonesian capital market a semi-strong form.