bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence Of Non O Blood Group In patients admitted with Ischemic stroke at Tertiary care center:A Descriptive Cross sectional Study
Authors: - Prasanna Bahadur Amatya , - Milan Khadka , - Nabin kumar sinjali magar , - Dr Umesh Bogati
Published: December 2024

Introduction: Stroke is characterized as a sudden occurrence of a neurologic deficiency caused by a focal vascular reason. Stroke is classified into two types: Hemorrhagic and Ischemic. The ABO blood groups can impact thrombosis by having elevated levels of VWF and factor VIIIc (possibly affected by an O(H) antigen-related change in VWF metabolism), along with increased acquired resistance to activated protein C observed in individuals without blood type O. The objective of this research is to identify a possible connection between ABO blood group and ischemic stroke within the Nepalese population. Such a study has not been conducted in Nepal previously.

Methods: A descriptive cross-sectional study was conducted in a tertiary care center after obtaining ethical approval from the Institutional Review Board (approval number 1149).Patients admitted to the hospital with clinical symptoms indicative of stroke and confirmed neuroimaging evidence of ischemic stroke during the study period from June 2020 to July 2024 were considered as cases. Subsequently, the ABO blood groups of the patients were recorded and statistically analyzed .

Results: 317 ischemic stroke patients underwent analysis of ABO blood grouping. Among them, 84% were found to have a non-O blood group. The examination of the correlation between ABO blood groups and ischemic stroke patients yielded a significant result.

Conclusions: There is indeed a link between ABO blood grouping and ischemic stroke, with a higher prevalence in individuals with non-O blood types
In-silico Studies of Some Novel Pyrazoline Derivatives Focusing on Melanoma, Antimicrobial and Anti-inflammatory Activity
Authors: - Muskan , - Kalpana devi , - Zohra jabeen
Published: December 2024

Microbial infections often produce pain and chronic inflammation, leading cause of cancer. The compound possessing anti-cancer potency with wide spectrum anti-microbial and anti-inflammatory activity is not common. Study focuses on designing a series of novel pyrazoline derivatives active towards anti-neoplastic, anti-microbial and anti-inflammatory response. The pyrazoline derivatives were investigated against the structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation and Crystal structure of antigen 43 from uropathogenic Escherichia coli UTI89. Furthermore, the antitumor activity of pyrazoline compounds was evaluated against the crystal structure of human melanoma-associated antigen B1 (MAGEB1). The reported data highlight the impact of chemical structure variations on biological activity. Specific structural modifications consistently altered activity across all tests. Introducing p-nitro and p-hydroxy groups into the aryl moiety of the pyrazoline analogs resulted in compounds with significant anti-inflammatory, antimicrobial, and anticancer properties. The enhanced activities are attributed to the presence of 4-NO₂, 4-OH, and 4-Cl groups in the phenyl ring at the 5-position of the pyrazoline ring. In certain cases, these compounds demonstrated activities equal to or exceeding those of standard drugs.
Overcoming Depression from Root Cause by Changing Internal Dominant Focus to Positivity by using Clinical Hypnosis with Eclectic Psychological Therapies
Authors: - Swati Rao Shiv
Published: December 2024

Abstract: This study is about using applied psychology to change internal dominant focus to the positive to heal severe depression and create motivation for work. The four cases cited here were suffering from severe depression when they came for therapy. The methodology employed an eclectic approach of using hypnosis along with psychoanalysis, psychodynamic therapy, age regression, dialectical behavior therapy and cognitive behavior therapy. The aim was to use different methods of applied psychology to shift the internal dominant focus to positive. The objectives were that the person starts focusing on positive aspects of life deliberately; Restarts taking interest in daily living activities like studying, bathing, eating, working etc.; Starts focusing on smaller achievable goals that make him/her feel positive. The tools used were methods of deepening to access the subconscious mind and the Beck’s Depression Inventory. The techniques were integrated such that about 8 to 30 hours of therapy was required depending on each case. After intensive healing and therapy was done, they could achieve positivity through some minor changes in their thinking patterns. Due to inner child healing, the internal dominant focus changed from negative to positive. The results were positive. The scores on Beck’s Depression Inventory were of severe depression and reduced to normal in all the four cases. The discussion and analysis showed that while the unipolar depression healed completely, bipolar symptoms reduced considerably but did not go away completely, indicating that bipolar depression could be chemically influenced.
Electron Cyclotron Resonance Thruster Technology: A Pathway to Efficient Spacecraft Propulsion
Authors: - Kezia Mariyam Thomas , - Shivani Verma
Published: December 2024

Electron Cyclotron Resonance (ECR) thrusters are emerging as a promising technology for efficient spacecraft propulsion, utilizing the phenomenon of
electron cyclotron resonance to generate thrust. This comprehensive review synthesizes key advancements, design strategies, and ongoing challenges within the field. ECR thrusters operate by heating electrons in a magnetized plasma using microwave energy, leading to high ionization rates and favorable thrust-to-power ratios. Unlike traditional propulsion systems, ECR thrusters
offer significant advantages, including higher specific impulse and reduced fuel consumption, making them ideal for long-duration space missions. The paper delves into various critical aspects of ECR thruster design, such as antenna configurations, gas injection methods, and magnetic field optimization, highlighting how these factors influence overall performance. It also discusses
the latest experimental findings and theoretical models that have addressed issues like efficiency, lifetime, and power transfer. Furthermore, the review explores future directions, emphasizing the need for advancements in
materials and automated impedance matching to enhance reliability and thrust generation capabilities.Through this analysis, the paper aims to present a holistic understanding of ECR thrusters, underscoring their potential to become a competitive and sustainable option for future space exploration.
The Impact of TRIPS-Driven Data Exclusivity on Pharmaceutical Innovation in India: Balancing Patent and Public Health
Authors: - Anuritha A , - Jayshree DS
Published: December 2024

The lack of data exclusivity regulations in India presents substantial issues to the pharmaceutical
sector, public health, and international trade compliance. Data exclusivity, which limits the reuse
of clinical trial data by generics manufacturers for a predetermined period of time, encourages
pharmaceutical innovation by preserving the investments of originator companies. India's present
structure allows generic manufacturers to exploit this data without the need for extra clinical
trials, which promotes affordable drug access and has helped India become a key global provider
of low-cost pharmaceuticals. However, this strategy raises questions about intellectual property
protection and compliance with the WTO's TRIPS Agreement rules. This research investigates
these ramifications via the lenses of industry, public health, and trade compliance. For the
pharmaceutical business, the lack of data exclusivity diminishes incentives for expensive R&D
investments, potentially limiting future drug development. Internationally, India's noncompliance
with data exclusivity norms affects trade ties with partners such as the United States and the
European Union, which complain that it limits market access for originator firms. Introducing
data exclusivity regulations could increase R&D investment, promote innovation, and strengthen
India's position in trade negotiations. A balanced strategy, combining data exclusivity with
measures for vital drugs and public health safeguards, would boost both innovation and access.
Next-Generation Sequencing in Haematological Diagnostics: Innovations and Clinical Applications
Authors: - Divas Srivastava
Published: December 2024

Next-generation sequencing (NGS) technologies have transformed haematological diagnostics, offering unparalleled speed, accuracy, and depth in analysing genetic variations linked to blood disorders and malignancies [1]. This review highlights the advancements and clinical applications of NGS, including its use in identifying clonal architecture, detecting minimal residual disease, and enabling personalised treatment strategies [2]. The integration of NGS into routine diagnostics has allowed for the precise identification of driver mutations, inherited blood disorders, and pharmacogenomic insights. Despite challenges such as data interpretation, assay validation, and accessibility, NGS remains a pivotal innovation in molecular diagnostics. Emerging technologies, including single-cell sequencing [3] and AI integration, promise to further revolutionise the field, ensuring that genomic insights translate into improved patient outcomes. This work underscores NGS's transformative impact on haematology, from early disease detection to the realisation of precision medicine [4].
The Convergence of Big Data and Generative AI: A Paradigm Shift in Data Analytics
Authors: - Akbar Sharief Shaik
Published: December 2024

The convergence of big data and generative artificial intelligence represents a transformative paradigm
shift in data analytics and processing capabilities. This comprehensive article review examines the
evolution, current state, and future implications of this technological integration across multiple sectors.
The article explores advanced learning paradigms, including few-shot and zero-shot learning, which have
revolutionized traditional machine learning approaches. The article delves into multimodal integration
capabilities that enable simultaneous processing of diverse data types, enhancing analytical accuracy and
decision-making processes. The article addresses critical technical implementation challenges, focusing
on computational infrastructure demands, environmental impact, and sustainability considerations.
Furthermore, the article examines crucial aspects of data privacy and ethical considerations, including
security protocols, bias mitigation, and regulatory compliance. The article analysis extends to practical
industry applications across healthcare, financial services, and manufacturing sectors, demonstrating
substantial improvements in operational efficiency and decision-making capabilities. This article
synthesizes current developments while providing insights into future directions and opportunities,
emphasizing the increasingly critical role of responsible AI development and implementation strategies.
AI in Financial Strategy: Continuous Monitoring for Enhanced Profitability
Authors: - Neeraj Kripalani
Published: December 2024

This article investigates the transformative impact of Artificial Intelligence (AI) in financial strategy through continuous monitoring systems designed to enhance organizational profitability. The article examines how AI-driven solutions analyze spending patterns, optimize resource allocation, and improve decision-making processes across various organizational contexts. Through comprehensive analysis of historical financial data and implementation of advanced machine learning algorithms, this research demonstrates significant improvements in cost reduction and budget optimization. The article reveals that organizations implementing AI-driven financial monitoring systems achieve substantial reductions in operational costs, enhanced accuracy in spending categorization, and improved financial decision-making capabilities. The article presents a systematic framework for implementing AI-based financial monitoring systems, including detailed methodologies for pattern recognition, expenditure analysis, and resource utilization assessment. Additionally, it explores the practical implications of AI integration in financial strategy, addressing both the opportunities and challenges organizations face during implementation. The article contributes to the growing body of knowledge on AI applications in financial management by providing actionable insights for organizations seeking to leverage artificial intelligence for improved financial performance and strategic decision-making.
Harnessing the Blue Economy: India's Path to Sustainable Marine Resource Utilization and Economic Growth
Authors: - Siddhant Naresh Pathak , - Vatsal Vyas
Published: December 2024

Blue Economy has introduced a completely new array of opportunities for India to expand upon its economy while having keeping an eye on the sustainability of its marine resources. It also helps that this idea implements perfectly with the strategic positioning of the coastline. India’s potential to increase its economic growth with the help of Blue Economy through various policies which could be implemented into its economic framework. India has even taken steps to promote this with various projects like the Sagar Mala Project or the Deep Ocean mission. The main focus right now should be based on the process of upgrading the infrastructure related to port, upgrading marine technology while also focusing and promoting sustainable aquafarming and preservation of marine resources. In simple words it strives to create of balance of both the economic growth as well the conservation of the aquatic resources and marine life. Marine sectors require investments but in return it will certainly lead to the boost in India’s GDP as it will lead to the many benefits like creating major job benefits, and it will improve the lifestyle of coastal communities. However, with such ambition the implementation of these policies remains a huge challenge, it requires more than just discussing policies it requires complete involvement from both the Government and the community. Overall, if India uses its tactically perfect positioning in terms of blue economy it could become of the biggest blue economic models in the world. India’s blue economy could contribute hugely to both the Nation and global efforts to spread the message of economic growth along with the preservation of the ocean life.
A Piece of Masterpiece: Contribution of Wasim Kapoor in The Field of Contemporary Art
Authors: - POULOMI BISWAS
Published: December 2024

This research paper is about the contemporary artist of Kolkata, Wasim Kapoor, and an analysis of his painting series, such as Rikshaws, Burkha, Prostitute, Victims and Silence, Adam and Eve, etc (Kolkata, 2004-2022). He was among the eminent artists of India who passed away recently on January 24, 2022. He was the son of Padam Shri recipient Salik Lucknawi, a renowned artist in his own right. Kapoor's upbringing in an artistic household and his early exposure to the art world significantly influenced his creative journey. He was a selfless activist who never backed off from injustice and fought for it himself. His paintings also focus on the subject of harsh reality and slavery in society. Wasim Kapoor always talked about the wrong things in society and how it should be ended. He believed in the young artists of today's generation for a change. Wasim Kapoor expresses his emotions through his paintings. His skilled hands have contributed a lot to this society. Some of his important series are the Burkha series, Jesus series, Prostitute series, Hand Rikshaw series, and Krishna series. There will be a proper discussion on his paintings' subject matter and concept. He said himself that 90% of his paintings are possessed by dark emotion and suffering. His childhood was full of illness and pain, which made him spend most of his childhood and teenage life in hospital beds. He started learning paintings in hospital beds. This paper is based on a personal interview with the Artist Wasim Kapoor on 1st March 2020, which was documented in mobile recording. It will explore the artist, his paintings, and the concepts behind his artworks.
A COMPARATIVE STUDY OF CAPITAL BUDGETING OF SELECTED NBFC’S
Authors: - Rithika Sidling , - Chippolu Nagaraja
Published: December 2024

(Capital budgeting is a crucial financial management process used by organizations to evaluate, select and prioritize long-term investment projects. These projects often involve significant capital expenditure and have a long-term impact on the organization’s profitability and growth. The current study evaluates the investment criteria of selected NBFCs in Karnataka. For the study purpose student selected 5 Non-Banking Financial Corporations and considered PBP and ARR methods for evaluation. For the analysis part Tabulation and Graphical representation methods are useful for interpretation.)
Diverse Teams, Better Outcomes: Exploring Diversity in Healthcare Management
Authors: - Madhulika Banerjee
Published: December 2024

Health policy and management research provides a crucial insight in this era of polarization and division among increasingly diverse communities: meaningfully embracing diversity through inclusive leadership, which welcomes employees from all levels of the organization and engages diverse viewpoints to make all healthcare workers feel free to express themselves and take part, can save lives. Through the definition of terms and discussions of the benefits of diversity, this article presents the importance of diversity in healthcare settings. In addition to analyzing the demonstrated benefits of diversity, our goal was to comprehend the obstacles that exist so that we might successfully remove them at the systemic, institutional, and individual levels.
Frequent Consumption Of Non-Vegetarian Food And Its Impact On Adult Health
Authors: - Bhavana Kadire , - Poonam Desai
Published: December 2024

The study Frequent Consumption of Non-vegetarian Food and its Impact on the Health of an Adult aims to evaluate the association between the frequency of non-vegetarian consumption and its potential health effects. It uses a descriptive study method, the Chi-Square test, and percentages. Most participants were young females, primarily students, with an overall sample size of 73. Half of them consumed non-veg once a week, while a significant number experienced gastric issues. The key finding was a strong association found between frequent non-veg consumption and heart disease risk. Also found that most of the individuals prefer Physical activity and a balanced diet as a health management strategy.
Exploring Women's Roles, Contributions, and Challenges in Medieval India from the 10th to 18th Century
Authors: - CHINMOY MANI
Published: December 2024

This paper explores the roles that women portrayed, the contributions they made, and the obstacles encountered during the medieval period in India, from the 10th to the 18th century. Drawing light on the status of women and the complex forces in that life, the analysis done above tries to unfold the socio-political, cultural, and economic background of the period under consideration. This research studies the social and cultural landscape, assessing how the caste system, religious practices, and gender norms have affected the roles that women have played out in various diverse places. Added to this in the study is further looking into the various ways through which the very significant dynasties of Rajputs, Mughals, and Deccan Sultanates were influencing the experiences of women. Therefore, a special focus would be placed on the roles women assume in political and administrative roles, particular to their involvement in specific positions like being rulers, regent moms, military leaders, and ambassadors. In addition, the influence of royal women in courts and assemblies and their contributions to governance and strategy is also probed, which essentially provides a comprehensive knowledge of the agency that the royal women possessed throughout this period and the problems that they encountered.
Revival of Tribal Fashion and Lifestyle: A Case Study of Western Odisha
Authors: - Dr. Sudhanshubala Tripathy , - Mrs. Shubhranshubala Tripathy
Published: December 2024

Odisha is a land of primitive tribal culture, full of picturesque colourful natural sceneries. It has inherited a wealth of traditional art and culture. In western Odisha, the elements of tribal cultural heritage have become a determining factor of the fashion trend. Most of the traditional tribal arts and crafts have come to find favour in the minds of art lovers and fashion designers not only in India but also in the world. On the contrary, due to a lack of proper training and sound technical knowledge, the tribals don’t find the means to promote their arts and natural creative skills. This paper focuses on the specific traditional art forms of tribals of Western Odisha and also advocates for the requirement of private-public support to promote local art and design in the global fashion industries and social media.
Projeto de Trabalho e Educação Matemática Crítica uma experiência nos anos finais do Ensino Fundamental
Authors: Milano Glauber da Silva , Olgin Clarissa de Assis
Published: December 2024

Este artigo apresenta um recorte de um estudo de mestrado que desenvolveu um Projeto de Trabalho com foco em Educação Financeira (EF), investigando suas contribuições para o ensino e a aprendizagem de Matemática sob a perspectiva da Educação Matemática Crítica (EMC) nos anos finais do Ensino Fundamental. A pesquisa justifica-se pela necessidade de contextualizar o Ensino de Matemática, utilizando a EMC como alternativa para promover reflexões mais profundas e críticas por meio dos conteúdos matemáticos. Além disso, destaca a importância de Projetos de Trabalho que desenvolvam competências relacionadas à Educação Financeira, preparando os alunos para lidar com questões financeiras e sociais. O objetivo da pesquisa foi examinar como o Projeto de Trabalho, fundamentado na EMC, poderia integrar a Educação Financeira com os conteúdos matemáticos. Com uma abordagem qualitativa, o estudo adotou uma pesquisa social interpretativa para captar as percepções dos alunos sobre as situações abordadas. Os resultados mostraram que o projeto permitiu que os estudantes, através da Matemática, interpretassem cenários cotidianos, tomassem decisões conscientes e refletissem sobre questões sociais. Dessa forma, o Projeto de Trabalho revelou ser uma abordagem que potencializa o processo de ensino e aprendizagem de Matemática de forma contextualizada, relacionando questões reais e promovendo o desenvolvimento de uma visão crítica nos alunos em relação aos temas abordados.
Strength and size relationships of toe flexor muscles in three different functional force production tasks
Authors: Kusagawa Yuki , Kurihara Toshiyuki , Maeo Sumiaki , Sugiyama Takashi , Kanehisa Hiroaki , Isaka Tadao
Published: December 2024

Purpose

Toe flexor strength (TFS) has been determined to evaluate the toe flexor muscle function. However, it is unclear how strength and size relationships of toe flexor muscles vary depending on the toes intended for force production. We aimed to clarify this by examining the relationship between TFS and toe flexor muscle size, and hypothesized TFS produced by all toes (TFS-All), the great toe (TFS-Great), and lesser toes (TFS-Lesser) would be specifically associated with the size of the muscles specialized in each corresponding toe flexion.

Methods

The maximal anatomical cross-sectional area (ACSAmax) of each toe flexor muscle was measured by magnetic resonance imaging in twenty healthy young men. The three types of TFS were measured using a custom-made toe push dynamometer.

Results

TFS-All was significantly associated with ACSAmax of the adductor hallucis transverse head (ADDH-TH) (r = 0.58, P = 0.01) and flexor hallucis brevis (FHB) (r = 0.56, P = 0.01). TFS-Great and TFS-Lesser were not significantly correlated with ACSAmax of any analyzed muscles, except for a significant correlation between TFS-Lesser and dorsal/plantar interosseous muscle (r = 0.48, P = 0.03).

Conclusions

The size of two plantar intrinsic foot muscles, FHB, anatomically specialized for the great toe flexion, and ADDH-TH, supplementary flex the great toe, may be the determinant for TFS-All. However, TFS-Great and TFS-Lesser are not associated with the size of the muscles anatomically specialized in each corresponding toe flexion, perhaps due to difficulty in maximally and separately activating individual muscles (i.e., neural/anatomical reasons) during the TFS-Great and TFS-Lesser production.
Kinetic characterization of adolescent scoliosis patients with Lenke 1B+
Authors: Huai Wang  , Rongchang Fu  , Kewei Yang
Published: December 2024

Purpose

The study purpose was to investigate dynamic responses of Lenke1B+ spines of adolescent scoliosis patients to different frequencies.

Methods

Modal analysis, harmonic response analysis, and transient dynamics of a full spine model inverted by the finite element method using Abaqus.

Results

The first-order axial resonance frequency of 4.51 Hz produced a maximum axial displacement of 30.15 mm. Comparison of the five frequencies indicated that the 10 Hz frequency response curve was smoothest, while the amplitude-frequency curve at 4 Hz showed the greatest fluctuations accompanied by resonance phenomena. At the resonance frequency, the maximum axial displacement of the thoracic spine was at T1, being 31.17 mm, while that of the lumbar spine was at L1, with 0.56 mm. The maximum stress of the intervertebral discs was located between T4 and T5, representing 3.496 MPa, and the maximum stress in the small joints was located in the concavity between T7 and T8, with 19.97 MPa, and the maximum axial displacement was 54.31 mm, located in the convexity between T6 and T7.

Conclusions

The first-order axial resonance frequency was the most harmful to the patient. The uneven stress distribution in the spine was closely related to the degree of spinal deformity, with the thoracic spine being more sensitive to low frequencies than the lumbar spine. The concave side of the spinal deformity was more prone to stress concentrations while the convex side was more prone to deformity, indicating that disc degeneration and small-joint disease are more likely to occur at the most deformed part of the spine.
Isokinetic strength and jumping abilities of teenage soccer players playing in different field positions
Authors: Górski Michał , Wilk Adrian , Pastuszak Anna , Starczewski Michał , Michalak Bartłomiej , Lane Michael T. , Buśko Krzysztof
Published: December 2024

Purpose

Soccer is a sport in which the game is played in a very dynamic manner. It requires soccer players to be able to develop high muscle force in a very short period of time. The aim of the study was to evaluate the strength and jumping abilities of young soccer players playing in different positions on the field.

Methods

The study included 49 adolescent soccer players: 6 goalkeepers, 15 defenders, 17 midfielders, and 11 strikers. We measured peak torques (PT), total work (TW), and average power (AP) developed by the knee flexors and extensors under isokinetic conditions at angular velocities of 60º*s-1, 180º*s-1, and 300º*s-1 on a Biodex dynamometer, and jump height (H) and maximum power (Pmax) on a force plate. PT, AP, TW, and Pmax scores were normalized relative to body mass.

Results

There were no statistically significant differences between measurements of basic somatic characteristics (body height and body weight) and age at peak height velocity (APHV) as well as PT, AP, TW, H, and Pmax in players from different positions on the field. Unlike defenders, midfielders showed a significant correlation of isokinetic tests indices with jump height (r = 0.54 ÷ 0.84) and maximum relative power (r = 0.55 ÷ 0.76).

Conclusions

The differences in correlations are probably due to the different tasks and activities that players in different positions on the field perform during the game.
Influence of heat treatment method on selected physicochemical and biological properties of fluoride-substituted calcium apatite
Authors: Borkowski Leszek , Zawislak Sylwia , Rutkowska Joanna , Trzaskowska Marta , Palka Krzysztof
Published: December 2024

Purpose

The synthesis of fluoridated apatite consists of several stages, among which the heat treatment has a significant impact on the physical and chemical properties. The present study aims to elucidate the influence of two different sintering methods on fluoride-substituted apatite properties.

Methods

For this purpose, a two F-substituted apatites were produced by heat treatment in different ways called “rapid sintering” and “slow sintering”. Physicochemical properties of the obtained materials were analyzed using infrared spectroscopy, scanning electron microscopy with energy dispersive spectrometry, X-ray diffraction, and mercury intrusion porosimetry. Cytotoxicity of materials was assessed using MTT test.

Results

Sintering conditions significantly influenced some porosity parameters of the materials. The samples subjected to “rapid sintering” showed a larger total pore area and mercury intrusion volume, while the samples subjected to “slow sintering” showed higher average pore diameter. Other porosity parameters did not differ significantly between the tested materials. The crystalline phases and chemical compositions of both materials were the same. Both materials appeared to be non-toxic since their extracts did not caused reduction in the viability of MC3T3-E1 cells compared to control cells and the results obtained were similar for both materials.

Conclusions

Sintering is an important step in the apatite synthesis process. The way apatite is sintered is a factor that influences its physicochemical properties. The study performed on fluoride-substituted apatite showed that sintering conditions influenced some porosity parameters but had no effect on composition, chemical structure or crystalline phase. The cytotoxicity of both materials was at the same level, indicating that both were non-toxic.
Evaluation of frictional wear in a follow-up screw-rod kinematic node in GGS transpedicular stabilization
Authors: Lichosik Justyna , Szkoda-Poliszuk Klaudia , Żak Małgorzata , Pezowicz Celina
Published: December 2024

Purpose

The aim of this study was to evaluate the abrasive wear of the sliding screw-rod joint used in growth guidance system (GGS) stabilizers, allowing the translation of the screw along the rod during the spinal growth process in a standard and modified system.

Methods

The study used single kinematic screw-rod pairs made of titanium alloy Ti6Al4V. Mechanical tests (cyclic loads) simulated the stabilizer's operation under conditions similar to actual use. A microscopic evaluation was conducted, analyzing abrasive wear based on measured abrasion areas. Numerical simulations were performed for the standard joint system and for a structural change (an additional insert to increase contact area between the rod and sliding screw cap).

Results

The study evaluated the abrasive wear of the mating elements of the stabilizer. Mechanical tests showed an increase in the force observed (11.74±2.52 N) with the increasing number of load cycles. Microscopic evaluation showed abrasion of the caps and rods in two areas (upper and lower). Numerical simulations indicated the highest stresses in the standard system were on the mating elements, i.e., the rod and the cap (15.6 MPa). In the modified joint, stress distribution differed, concentrating on the surface of the insert and the rod, with maximum values of 6.0 MPa (PE insert) and 12.4 MPa (PEEK insert).

Conclusions

Comparing the stress distributions obtained in the numerical simulations and the abrasive wear effects produced in the mechanical tests, a similar mechanism was observed (the destruction of the top layer of the mating elements of the stabilizer).
Pengembangan Media Gaul (Game Edukasi Wordwall) Pada Pembelajaran IPAS Kelas IV SD Negeri 161 Palembang
Authors: Listriyana Meiriska
Published: December 2024

Penelitian yang dilakukan merupakan jenis penelitian dan pengembangan Research and Development (RnD) untuk mendapatkan atau menghasilkan suatu media dan menggunakan prosedur penelitian dan pengembangan ADDIE yang memiliki lima (5) tahap yaitu analysis, Design, Development, implementation, dan evaluation. Berdasarkan hasil validasi yang diberikan penilaian oleh validator ahli maka persentase yang diperoleh dari nilai rata-rata kevalidan media mendapatkan skor 88% dengan kategori sangat valid. Tingkat kepraktisan media GAUL (Game Edukasi Wordwall) dilakukan dengan uji coba one to one dengan mengikutsertakan 3 orang peserta didik dengan memberikan angket respon peserta didik dan memperoleh tanggapan positif dari peserta didik dan memperoleh skor 93,9% coba small group sebanyak 12 orang peserta didik dengan memperoleh keseluruhan persentase sebesar 89,5% dengan kategori sangat praktis. Untuk melihat kemampuan peserta didik dalam memahami pembelajaran IPAS pada Bab 7 Topik A (Aku dan Kebutuhanku) Pada tahap uji coba kelompok besar subjek uji coba ialah seluruh peserta didik kelas IV A sebanyak 34 peserta didik, dalam pengembangan media GAUL (Game Edukasi Wordwall) ini juga dinyatakan memiliki keefektifan dalam proses pembelajaran menghasilkan nilai dengan rata-rata 88% dengan kategori sangat efektif.
Kata kunci: Permainan Edukasi, Wordwall, IPAS.
Üniversite Öğrencilerinin Tek Başınalık Deneyimi Üzerine Nitel Bir Çalışma
Authors: Özçelik Erdi , Bilge Filiz
Published: December 2024

Bu çalışmanın amacı üniversite öğrencilerinde tek başınalığın nasıl deneyimlendiği, tek başınalık sürecinde neler yapıldığı, tek başınalığın sonuçlarının ve etkilerinin neler olabileceğinin ortaya konmasıdır. Çalışma nitel yöntem ile yürütülmüştür. Çalışmada katılımcıların öznel deneyimlerine odaklanılması nedeniyle fenomenolojik desenden yararlanılmıştır. Katılımcılar İstanbul ilinde eğitimlerine devam eden 12 üniversite öğrencisinden oluşmaktadır. Öğrenciler amaçlı örnekleme yöntemlerinden maksimum çeşitleme ve kartopu örnekleme ile çalışmaya dâhil edilmiştir. Araştırma verileri yarı yapılandırılmış görüşmeler ile toplanmıştır. Görüşmeler 2023 yılının bahar aylarında yüz yüze yapılmıştır. Verilerin çözümlenmesinde tematik analiz kullanılmıştır. Araştırma sonucunda dört temaya ulaşılmıştır; belirleyiciler, içsel motivasyon, aktiviteler ve sonuçlar. Araştırma sonucunda tek başınalık modeli geliştirilmiştir. Geliştirilen modele göre üniversite öğrencilerinin tek başınalık deneyimini belirleyen bazı koşulların olabileceği, bu koşulların tek başınalık motivasyonunu ve tek başınayken yapılacak aktiviteyi etkileyebileceği, yapılan aktivitelerle birlikte tek başınalık deneyiminin olumlu, olumsuz ve sosyal bazı etkilerinin olabileceği sonucuna ulaşılmıştır. Çalışmada ulaşılan sonuçlar alanyazın bağlamında tartışılarak bazı önerilerde bulunulmuştur.
Modeling and Analysis of Multiconductor Transmission Lines by Distributed Transfer Function Method
Authors: Yang Bingen
Published: December 2024

Multiconductor transmission lines (MCTLs) have various applications in electrical engineering. In modeling and analysis of MCTLs, which are described by a set of coupled partial differential equations, most existing methods rely on approximation or discretization. For high-speed high-frequency applications, accurate analytical methods are always desirable. Such a method, however, is not currently available for complex MCTLs. This paper presents an innovative analytical method for modeling and analysis of MCTLs with various configurations. The proposed method, which is called the Distributed Transfer Function Method, is capable of delivering closed-form analytical solutions for complex MCTLs, in both the frequency domain and the time domain. One highlight of the proposed method is that it gives exact and closed-form solutions for branched transmission lines for the first time. The accuracy, efficiency, and high-frequency utility of the method is demonstrated in numerical examples.
Bioaccumulation of environmental pollutants and marine toxins in bivalve molluscs: a review
Authors: Ochoa-Esteso Clara , Roselló-Carrió Alba , Carrasco-Correa Enrique Javier , Lerma-García María Jesús
Published: December 2024

Seafood is both nutritionally and economically significant, with bivalve molluscs being particularly valuable for monitoring environmental pollutants due to their filter-feeding nature and ability to bioaccumulate pollutants. While not often linked to food poisoning, these molluscs can occasionally introduce health risks, highlighting the need for vigilant monitoring. This review provides a thorough analysis of pollutants—including persistent and emerging pollutants, as well as marine toxins—found in bivalve molluscs between 2019 and 2024. Among the studied pollutants, plasticizers and alkaloids are the most frequently analyzed, with liquid and gas chromatography (GC) tandem mass spectrometry (MS) the predominant methods, although novel approaches to determine these compounds, such as sensors, have also emerged in recent years. However, many studies are focused on establishing pollutant content without addressing bioaccumulation (BA) factors, and a lack of standardization in species and sampling locations complicates comparisons between the different published works. Despite some studies linking human activity and algal blooms to BA dynamics, more comprehensive research is needed. Additionally, limited data on the depuration capacity of molluscs underscores the need for further investigation. Although pollutant levels generally remain within legal limits, many substances remain unregulated. Environmental factors also play a critical role in influencing BA, emphasizing the need for future studies to focus on BA factors to better understand these complex dynamics.
Evaluating the Strength and Durability Properties of Geopolymer-Stabilized Soft Soil for Deep Mixing Applications
Authors: Naeem Zahraa Tawfiq , Al-Adhadh Ahmed Raad , Wazi Thair Hummod
Published: December 2024

Soft soil poses serious challenges and is unsuitable for engineering projects because of its insufficient bearing capacity, low shear strength, and high compressibility. Deep soil mixing (DSM) is one of the most popular methods of enhancing soft soil qualities, such as increased bearing capacity and reduced settling, which are critical for building any structure. The environmental effects of creating binders such as cement and lime make it crucial to identify alternative materials for geotechnical applications. This study employed fly ash (class C) --based geopolymer to investigate its effectiveness as an environmentally friendly substitute for cement for DSM applications. The experimental program included unconfined compressive strength, flexure strength, and durability tests. The parameters in the study are binder content (10, 15, and 20%) and activator/binder ratio (0.4, 0.6). Results revealed that UCS and flexural strength, GP-treated soil were in the range of 0.9–5.3 and 0.8–1.5 MPa, respectively (depending on the ratio of fly ash and activator). These strengths were even higher than those of cement-stabilized soil. The geopolymer-treated specimens exhibited excellent endurance over the wetting-drying cycle, with a modest weight loss of less than 4.5%. A binder dosage of more than 10% and an AC ratio of 0.6 were recommended to meet DSM application guidelines. The current study concludes that employing a fly ash-geopolymer binder to stabilize soft soil is an effective alternative to cement in DSM applications.
TECHNOLOGY FOR IN VITRO REARING OF PARASITICS
Authors:   Researcher, Vice Dean - Tashkent State University of Economics, Uzbekistan, Khidoyatova Khabiba , Jumaev Rasul ,   Professor, Doctor of Agricultural Sciences, Tashkent State Agrarian University, Uzbekistan
Published: December 2024

The technology of in vitro propagation of parasitic entomophages is a very important process. This direction is very important for the agricultural economy. An average of 1.8-2.2 million dollars is spent on the propagation of parasitic entomophages in our country per year. If we introduce the technology of in vitro propagation of parasitic entomophages, this will reduce costs by 2-3 times. Propagating parasitic organisms in this way will save significant economic costs.

The studies on in vitro rearing Hymenoptera have been conducted successfully in Uzbekistan. For these parasites, cooking and the three main types of media were made from the hemolymph of the wax moth (G.melonnella) and cotton worm Helicoverpa armigera (Heliothis armigera), egg yolk, natural milk 10%. Mass production of in vitro reared Braconidae and Trichogrammatidae its utilization in the fields showed good effectiveness in controlling agricultural economy.
PEER SUPPORT AND ADOLESCENT DEVIANT BEHAVIOR: THE IMPLICATION OF TEACHING LEARNING PROCESS IN MEZAM DIVISION, NORTHWEST REGION OF CAMEROON
Authors:   Department of Educational Psychology, Faculty of Education, University of Bamenda, Cameroon, Cameroon, Akongnwi Tanifum Francis , Mboshi Nsagha Sarah ,   Ph.D, Department of Educational Psychology, Faculty of Education, University of Bamenda, Cameroon, Cameroon, Wirdze Lambert ,   Ph.D, Department of Educational Psychology, Faculty of Education, University of Bamenda, Cameroon, Cameroon
Published: December 2024

The study was carried out to investigate the influence of peer support on adolescent deviant behavior in some selected secondary schools in Mezam Division, Northwest Region of Cameroon. Through a comprehensive mixed-methods approach utilizing a concurrent nested research design, the researchers gathered data from multiple perspectives, including 533 students, 25 disciplinary masters, and 20 guidance counselors across selected secondary schools. The methodological rigor of the study was enhanced by employing various data collection instruments, including questionnaires, interview guides, and focus group discussions. This triangulation of methods allowed for a deeper understanding of the complex dynamics between peer support and behavioral outcomes. The quantitative analysis, conducted using both descriptive and inferential statistics, provided a systematic examination of the relationships between variables. Specifically, the use of Spearman's rho correlation test was justified by the non-normal distribution of the data, as confirmed by normality assumption testing. The qualitative component of the study, analyzed through thematic analysis, complemented the quantitative findings by providing rich, contextual insights into the phenomenon. The study's findings demonstrated a significant negative correlation between peer support and deviant behavior (R-value = -0.237**, p-value 0.000 < 0.05). This inverse relationship indicates that as peer support increases, there is a corresponding decrease in deviant behavior among adolescents. This finding has important implications for educational practice and policy, suggesting that fostering positive peer relationships and support systems within schools could serve as an effective strategy for reducing behavioral problems among adolescent students.
Anal Squamous Cell Carcinoma: From Standard Treatment to Personalized Therapy
Authors: Basree Mustafa M. , Hutten Ryan , Sodji Quaovi , Bassetti Michael F. , Miller Jacob A.
Published: December 2024

Anal squamous cell carcinoma (ASCC) is a rare but increasingly prevalent disease, predominantly driven by human papillomavirus infection, with decreasing prevalence among individuals of vaccination-eligible age. In this review, we discuss both the current standard of care and future approaches for managing ASCC. There is interest in de-escalating therapy to minimize treatment-related morbidity, with studies such as DECREASE and PLATO currently ongoing. The integration of liquid biopsies as well as molecular biomarkers into clinical practice offers an exciting new frontier for personalized ASCC treatment. The future of anal cancer management lies in a personalized, biomarker-driven approach, which holds promise to transform clinical decision-making and enhance both the quantity and quality of life for patients with ASCC.
Anti-Racist Archival Description
Authors: Schilling Angela
Published: December 2024

For those whose stories are in the archives, accessing them can prompt many emotions and reactions. People accessing these records, and those processing and providing access to them, may be affected by their contents.
There are many things we can do as archivists and archival institutions to make this process easier, more accessible, and safer for those who experience direct or intergenerational trauma. The profession has access to a growing selection of tools to guide our protocols and practices, such as the Tandanya Declaration, the ATSILIRN protocols and UNDRIP, as well as case studies for high-level institutional changes and cultural shifts, though this process is arguably only at the beginning of its collective journey. However, there are often immediate and practical ways in which we can implement anti-racist archival practice, including the way we describe archival materials.
This paper will discuss practical ways in which archivists can actively undertake anti-racist description work, and why it is imperative that this work becomes a priority in our collection management work. It will draw on the comprehensive document Anti-Racist Description Resources, authored by the Archives for Black Lives in Philadelphia’s (A4BLiP) Anti-Racist Description Working Group, as well as other standards and sources.
Research, Access, and Digitisation: Reflections on Responsible Stewardship in the Online Era
Authors: Moran Jessica
Published: December 2024

This article reflects on the impact of digitisation programs for researcher access to archival materials. Using the author’s experience as both a researcher using digitised material and as a manager of archival programs, the article considers the opportunities and challenges of researcher demand for digital access and suggests the archival value of responsible stewardship is a useful concept when navigating access in the online era.
Paper Elephants: Reflections on Changing Archival Practice at the Australian Museum
Authors: Finney Vanessa
Published: December 2024

The archives of Australia’s first museum, the Australian Museum (AM) in Sydney, are an artefact of colonialism, still intertwined with the complexities of science, public museums, and imperialism. It’s the elephant in the archival room. However, change has come to Australia’s colonial-era museums, affecting their missions, historical framing, and collections and archives. This article provides a brief history of knowledge at the AM in order to showcase some current initiatives aimed at opening its archival holdings to new perspectives, encounters, shared knowledge, and a protocols-based approach to access. Understanding the history of the museum and its archival structures and methods is vital for rethinking a more open, generous, and responsible future for this important collection.