bluuebunny/crossref_metadata_2025 huggingface dataset:
Flood inundation forecasts using validation data generated with the assistance of computer vision
Authors: Bhola Punit Kumar , Nair Bhavana B. , Leandro Jorge , Rao Sethuraman N. , Disse Markus
Published: December 2018

Forecasting flood inundation in urban areas is challenging due to the lack of validation data. Recent developments have led to new genres of data sources, such as images and videos from smartphones and CCTV cameras. If the reference dimensions of objects, such as bridges or buildings, in images are known, the images can be used to estimate water levels using computer vision algorithms. Such algorithms employ deep learning and edge detection techniques to identify the water surface in an image, which can be used as additional validation data for forecasting inundation. In this study, a methodology is presented for flood inundation forecasting that integrates validation data generated with the assistance of computer vision. Six equifinal models are run simultaneously, one of which is selected for forecasting based on a goodness-of-fit (least error), estimated using the validation data. Collection and processing of images is done offline on a regular basis or following a flood event. The results show that the accuracy of inundation forecasting can be improved significantly using additional validation data.
Impact of upstream runoff and tidal level on the chlorinity of an estuary in a river network: a case study of Modaomen estuary in the Pearl River Delta, China
Authors: He Yanhu , Chen Sha , Huang Ruizhen , Chen Xiaohong , Cong Peitong
Published: December 2018

Saltwater intrusion exerts great impact on water supply and water withdrawal from estuarine areas. A chlorinity prediction model based on backpropagation neural network was constructed, calibrated, and validated, considering phase lags, with the Modaomen estuary in the Pearl River Delta (PRD), China as case study. This study aimed to investigate impacts of upstream runoff and tidal level on the changing properties of estuarine chlorinity. Nine boundary conditions – low tide and tidal range both with three different frequencies – were designed to explore the changing process of estuarine chlorinity and obtain the critical upstream runoff for saltwater suppression. Results indicated the model performed efficiently; Nash–Sutcliffe efficiency coefficient and R2 were both 0.91 in training period, 0.76 and 0.82 in testing period, and 0.64 and 0.77 in validation period, respectively, and estuarine chlorinity shows slightly different changing processes of decline rate under the nine boundary conditions when the upstream runoff increases. The higher the designed tidal range and lower daily tides together with the smaller the amount of upstream runoff, the higher the estuarine chlorinity. The critical upstream runoff of the Pinggang pumping station is 2,500 m3/s. These findings provide a foundation for water supply security and upstream reservoir dispatching in estuarine areas in dry periods.
Motivators for treated wastewater acceptance across developed and developing contexts
Authors: Rice Jacelyn , Stotts Rhian , Wutich Amber , White Dave , Maupin Jonathan , Brewis Alexandra
Published: December 2018

As water scarcity increases, we must turn to underutilized sources such as treated wastewater. While work has been done on barriers to public acceptance, less work has been undertaken to explore motivations that may incentivize adoption of this potential water source. Using data collected from respondents in four global sites (in Guatemala, Fiji, New Zealand, and Spain), we (1) analyzed how four motivators (cost, current and future water shortages, and ecological conservation) influenced respondents' willingness to use treated wastewater and (2) examined if respondents' willingness varied across contexts based on the level of wastewater treatment available. Despite a focus in previous research on the role of reducing cost and providing economic incentives for wastewater reuse adoption, cost was broadly the least motivating factor while ecological conservation and future water shortages were the two strongest motivators across all sites. Additionally, respondents in sites with low levels of wastewater technology were more likely to express a willingness to use treated wastewater given any motivator.
Mesoporous Silica Nanoparticles as a Prospective and Promising Approach for Drug Delivery and Biomedical Applications
Authors: Pu Xiaohui , Li Jia , Qiao Peng , Li Mengmeng , Wang Haiyan , Zong Lanlan , Yuan Qi , Duan Shaofeng
Published: December 2018

Background:

With the development of nanotechnology, nanocarrier has widely been applied
in such fields as drug delivery, diagnostic and medical imaging and engineering in recent
years. Among all of the available nanocarriers, mesoporous silica nanoparticles (MSNs) have become
a hot issue because of their unique properties, such as large surface area and voidage, tunable
drug loading capacity and release kinetics, good biosafety and easily modified surface.

Objective:

We described the most recent progress in silica-assisted drug delivery and biomedical applications
according to different types of Cargo in order to allow researchers to quickly learn about
the advance in this field.

Methods:

Information has been collected from the recently published literature available mainly
through Title or Abstract search in SpringerLink and PubMed database. Special emphasis is on the
literature available during 2008-2017.

Results:

In this review, the major research advances of MSNs on the drug delivery and biomedical
applications were summarized. The significant advantages of MSNs have also been listed. It was
found that the several significant challenges need to be addressed and investigated to further advance
the applications of these structurally defined nanomaterials.

Conclusion:

Through approaching this review, the researchers can be aware of many new synthetic
methods, smart designs proposed in the recent year and remaining questions of MSNs at present.
Application of the Co-Agonist Concerted Transition Model to Analysis of GABAA Receptor Properties
Authors: Germann Allison L. , Steinbach Joe Henry , Akk Gustav
Published: December 2018

The co-agonist concerted transition model is a simple and practical solution to analyze various aspects of GABAA receptor function. Several model-based predictions have been verified experimentally in previous reports. We review here the practical implications of the model and demonstrate how it enables simplification of the experimental procedure and data analysis to characterize the effects of mutations or properties of novel ligands. Specifically, we show that the value of EC50 and the magnitude of current response are directly affected by basal activity, and that coapplication of a background agonist acting at a distinct site or use of a gain-of-function mutation can be employed to enable studies of weak activators or mutated receptors with impaired gating. We also show that the ability of one GABAergic agent to potentiate the activity elicited by another is a computable value that depends on the level of constitutive activity of the ion channel and the ability of each agonist to directly activate the receptor. Significantly, the model accurately accounts for situations where the paired agonists interact with the same site compared to distinct sites on the receptor.
Sense of Smell: Structural, Functional, Mechanistic Advancements and Challenges in Human Olfactory Research
Authors: Sharma Anju , Kumar Rajnish , Aier Imlimaong , Semwal Rahul , Tyagi Pankaj , Varadwaj Pritish
Published: December 2018

Olfaction, the sense of smell detects and discriminate odors as well as social cues which influence our innate responses. The olfactory system in human beings is found to be weak as compared to other animals; however, it seems to be very precise. It can detect and discriminate millions of chemical moieties (odorants) even in minuscule quantities. The process initiates with the binding of odorants to specialized olfactory receptors, encoded by a large family of Olfactory Receptor (OR) genes belonging to the G-protein-coupled receptor superfamily. Stimulation of ORs converts the chemical information encoded in the odorants, into respective neuronal action-potentials which causes depolarization of olfactory sensory neurons. The olfactory bulb relays this signal to different parts of the brain for processing. Odors are encrypted using a combinatorial approach to detect a variety of chemicals and encode their unique identity. The discovery of functional OR genes and proteins provided an important information to decipher the genomic, structural and functional basis of olfaction. ORs constitute 17 gene families, out of which 4 families were reported to contain more than hundred members each. The olfactory machinery is not limited to GPCRs; a number of non- GPCRs is also employed to detect chemosensory stimuli. The article provides detailed information about such olfaction machinery, structures, transduction mechanism, theories of odor perception, and challenges in the olfaction research. It covers the structural, functional and computational studies carried out in the olfaction research in the recent past.
Green Synthesis of Hydantoins and Derivatives
Authors: López-López Lluvia Itzel , de Loera Denisse , Rivera-Avalos Ernesto , Sáenz-Galindo Aidé
Published: December 2018

The hydantoin moiety is found in several bioactive compounds with important pharmacological properties such as antimicrobial, antifungal, anti-androgens, anticancer and the historical action anticonvulsant. Because of these reasons, the synthesis of these compounds and their derivatives is important to review considering the philosophy of the green chemistry. In this review, we present the actual importance in the green synthesis of hydantoins and their derivatives using green methods, such as microwave and ultrasound irradiation, ionic liquids, solid-phase and solvent-free synthesis. Finally, several green protocols reported have been discussed.
Evaluation of Cytotoxic Potentials of Some Isoindole-1, 3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines
Authors: Tan Ayse , Yaglioglu Ayse Sahin , Kishali Nurhan Horasan , Sahin Ertan , Kara Yunus
Published: December 2018

Objective:

Considering this information, firstly, isoindole derivatives containing different functional
groups 4-13 have been synthesized from 2-alkyl/aryl-3a, 4,7,7a-tetrahydro-1H-isoindole-1,
3(2H)-dione.

Background:

Norcantharimides are known as norcantharidine derivatives and contain
an isoindole skeleton structure. Isoindole derivatives have positive effect on inflammatory pathologies
including cancers.

Methods:

For the synthesis of all compounds, 2-alkyl/aryl-3a, 4,7,7a-tetrahydro-1H-isoindole-
1,3(2H)-dione was used as the starting compound. The syntheses were based on two main reactions:
Ene-reaction of singlet oxygen and epoxidation. Secondly, their anticancer activities were
evaluated against HeLa, C6 and A549 cancer cell lines by the BrdU assay.

Results:

Anticancer activities of synthesized compounds (4-13) and 5-FU (5-Florouracil) against
HeLa, C6 and A549 cells were investigated at four concentrations (100, 50, 25 and 5 μM). IC50
values of compounds 4-13 were calculated for all cancer cell lines. The investigated compounds
showed anticancer activity against the cancer cell lines depending on doses. Compound 7 containing
azide and silyl ether exhibited higher inhibitory activity than the other compounds and 5-FU
against A549 cancer cell lines (IC50 =19.41± 0.01 μM). Compounds 9 and 11 were determined to
exhibit cell-selective activity against HeLa cancer cell lines. Compound 11 had higher activity than
the positive control at 100 μM concentrations against C6 cancer cell lines.

Conclusion:

According to the results observed, isoindole derivatives 7, 9, and 11 might be good
potential anticancer agents for the treatment of cervical and glioma cancer due to their antiproliferative
properties, having less cytotoxic effects on healthy cells. In addition, compound 7 could be
used in in vivo studies of all three-cancer cell lines (C6, HeLa, and A549).
Melamine Detection in Food matrices employing Chicken Antibody (IgY): A Comparison between Colorimetric and Chemiluminescent Methods
Authors: Sushma Umesh , Srivastava Alok K. , Krishnan Manonmani H.
Published: December 2018

Background:

Melamine, contains 67% nitrogen by mass, and is adulterated in foods to uplift false protein. There is an urgent requirement to develop fast screening techniques for monitoring melamine in foods.

Objective:

To develop rapid, high throughput detection techniques for melamine in the food matrix.

Methods:

IgY antibodies were developed against melamine in the hen, isolated and used for detection of melamine. The detection by colorimetric and chemiluminescent methods was compared.

Results:

The detection range for melamine was 1 ng-25 µg by the colorimetric method and 10 fg/mL-25 ng/mL by the chemiluminescent method. There was a very low matrix effect, where the recovery was 86 to 106 % by colorimetric method and 71 to 98 % by the chemiluminescent method.

Conclusion:

Both colorimetric and chemiluminescent methods could be employed for the fast and consistent melamine detection in the food matrix.
Study of the Fragmentation Pathways of Sulfonamides by High-resolution Mass Spectrometry: Application to their Detection in Plasma by Direct Infusion
Authors: Kokotou Maroula G.
Published: December 2018

Background:

The high resolving and accuracy power of the HRMS instrument enabled us to
identify the product ions and to propose detailed fragmentation pathways and diagnostic fragment ions.

Methods:

In the present work, the fragmentation pathways of five sulfonamides antibiotics, namely
sulfamerazine, sulfathiazole, sulfadiazine, sulfadimethoxine and sulfamethoxazole, by High-Resolution
Mass Spectrometry (HRMS) are presented. The HRMS spectra were recorded with a Q-TOF (Time of
Flight) spectrometer with Electrospray Ionization (ESI) in both negative and positive mode.

Results:

Specific characteristic ions for each one of the sulfonamide antibiotics under positive ESI
mode are proposed for the first time. Fragment ions of this particular class of analytes may be used to
rapidly identify compounds with common structural features.

Conclusion:

The direct infusion of plasma samples, avoiding any prior chromatographic steps, to identify
the existence of sulfonamide antibiotics is demonstrated herein.
Prolactin Induces IL-2 Associated TRAIL Expression on Natural Killer Cells from Chronic Hepatitis C PatientsIn vivoandIn vitro
Authors: Medel Maria L.H. , Reyes Gabriela G. , Porras Luz M. , Bernal Arturo R. , Luna Jesús S. , Garcia Adolfo P. , Cordova Jacqueline , Parra Adalberto , Mummidi Srinivas , Kershenobich David , Hernández Joselín
Published: December 2018

Background:

Natural killer cells (NKC) are a major component of the innate immune response to HCV, mediating their effects through TRAIL and IFN-γ. However, their function is diminished in chronic HCV patients (HCVp). Prolactin is an immunomodulatory hormone capable of activating NKC.

Objective:

The study aims to explore if hyperprolactinemia can activate NKC in HCVp.

Methods:

We treated twelve chronic HCVp (confidence level =95%, power =80%) for 15 days with Levosulpiride plus Cimetidine to induce mild hyperprolactinemia. Before and after treatment, we determined TRAIL and NKG2D expression on peripheral blood NKC, along with cytokine profiles, viral loads and liver function. We also evaluated in vitro effects of prolactin and/or IL-2 on NKC TRAIL or NKG2D expression and IFN-γ levels on cultured blood mononuclear cells from 8 HCVp and 7 healthy controls.

Results:

The treatment induced mild hyperprolactinemia and increased TRAIL expression on NKC as well as the secretion of IL-1ra, IL-2, PDGF and IFN-γ. Viral loads decreased in six HCVp. IL-2 and TRAIL together explained the viral load decrease. In vitro, prolactin plus IL-2 synergized to increase TRAIL and NKG2D expression on NKC from HCVp but not in controls.

Conclusion:

Levosulpiride/Cimetidine treatment induced mild hyperprolactinaemia that was associated with NKC activation and Th1-type cytokine profile. Also, an increase in TRAIL and IL-2 was associated with viral load decrease. This treatment could potentially be used to reactivate NKC in HCVp.
ACO Inspired Computer-aided Detection/Diagnosis (CADe/CADx) Model for Medical Data Classification
Authors: Dhull Anuradha , Khanna Kavita , Singh Akansha , Gupta Gaurav
Published: December 2018

Background:

Computer-Assisted Diagnosis (CAD) has become a common practice of
use in the healthcare industry due to its improved accuracy and reliability. The CAD systems are expected
to improve the quality of medical care by assisting healthcare professionals with a wide range
of clinical decisions. A CAD system is a combination of Computer-Assisted Detection (CADe) and
Computer-Assisted Diagnosis (CADx) system.

Objective:

The objective of this research article is to generate an optimized rule-set for medical diagnosis
capable of providing improved accuracy. It is evident from the literature that keeping a balance
between these performance parameters is a real challenge.

Methods:

In order to achieve the desired objective, the following two contributions have been proposed
to improve diagnosis accuracy: 1) an unsupervised feature selection approach based on ACO
Meta-heuristic is used to design the CADe system, and 2) an ACO assisted decision tree classifier
technique is employed to make CADx system.

Results:

Three popular UCI (Wisconsin Breast Cancer, Pima Indian Diabetes and Liver Disorder)
medical domain datasets have been used to evaluate the performance of the proposed model. The
exploratory result analysis shows the efficiency of the proposed work as compared to existing work.
Grimmia (Grimmiaceae, Bryophyta) in southern Mexico (Oaxaca and Chiapas)
Authors: Delgadillo Moya Claudio , Peña Retes Ana Paola
Published: December 2018

Background and Aims: The taxonomy and distribution of Grimmia are well known because of recent reviews in global, continental, and regional studies. However, collections from some areas like southern Mexico are scarce. This study updates the distribution of Grimmia in southern Mexico and attempts to revise the hypothesis of its geographical distribution.Methods: Field work in Oaxaca and Chiapas complemented records in a Neotropical database of Grimmia. Collections from these states partly validated models of potential distribution for several species prepared in a previous study.Key results: There are three species of Grimmia in southern Mexico: G. longirostris, G. pilifera, and G. trichophylla. The last species is the only record for Chiapas where it is associated with other temperate and subtropical mosses.Conclusions: Its known range in Mexico, as supported by the study of more than 900 specimens from this country, suggests that Grimmia arrived from North America, not from a southern origin because key species have not been found in Oaxaca and Chiapas.
Некоторые вопросы гидродинамики и энергетики циркуляторного и гемического звеньев системы транспорта кислорода (часть 3)
Authors: Mikhnevich K.G.
Published: December 2018

В 3-й части статьи представлен обновленный подход к изучению кислородного бюджета с учетом энергетического потенциала доставляемого кислорода и предложен принцип нормировки гемодинамических показателей на основе расчета транспорта энергии. Рассмотрены энергетические аспекты вариантов острого нарушения кровообращения. Приведена разработанная биомедицинская система единиц измерения.
Su Ürünleri Yetiştiriciliğinde Tıbbi Bitkilerin Anestezik Olarak Kullanımı
Authors: METİN Seçil , DİLER Öznur , DİDİNEN Hakan
Published: December 2018

Su ürünleri yetiştiriciliğinde anestezik veya sedatifler; sakinleştirme, balıkları hareketsiz bırakma ve uzun
süreli nakiller için gereklidir. Günümüzde en yaygın olarak kullanılan anestezikler MS222, benzokain ve 2-
fenoksietanol (2-PE) olarak sıralanabilir. Fakat bu kimyasalların kalıntıları insan ve hayvan sağlığı açısından
olumsuz etkilere sahiptir. Bu nedenle balıketinde kalıntı yapmayan, balık tarafından iyi tölere edilen, vücuttan
atılma süresi kısa dolayısıyla insan ve hayvan için daha güvenli olan doğal ürünlere gereksinim
duyulmaktadır. Bu derlemede su ürünleri yetiştiriciliğinde kullanılabilecek farklı tıbbi bitkilerin farklı balık
türlerindeki anestezik etkileri üzerine yapılmış çalışmalar ele alınmıştır.
Maximum size of Bogue, Boops boops (Perciformes: Sparidae) for the Mediterranean
Authors: CEYHAN Tevfik , ERTOSLUK Okan , AKYOL Okan , ÖZGÜL Aytaç
Published: December 2018

A specimen of Boops boops, 402 mm in total length (986 g weight), was caught on 27 March 2018 by gill
net from Güllük Bay on the muddy bottom at a depth of 55 m. This record is the maximum size both for
Turkish seas and Mediterranean basin.
Da geosofia como geografia cordial: a obra de Josué de Castro como insurreição ontológica / Geosophy as a cordial geography: Josué de Castro's work as an ontological insurrection
Authors: Galvão Filho Carlos Eduardo Pontes
Published: December 2018

A geosofia como conhecimento geográfico emergido da geograficidade e feita de sentimentos de mundo estabelecidos nas experiências geográficas de paisagens, territórios e lugares. Experiências ora de aproximação ora de distanciamento da própria condição terrestre, oscilação de referências e vinculações que vibram à flor da pele no existir do ser-no-mundo. Nesse sentido, a geosofia é conhecimento que desvela a dimensão geográfica do habitar e abre caminhos para um pensar junto ao coração: uma geografia cordial que pulsa junto à Terra. O objetivo deste artigo é cultivar a possibilidade da geosofia como geografia cordial e esta como um pensar insubordinado quanto à cisão homem-Terra que marca o pensamento moderno euro-ocidental. A obra de Josué de Castro aparece enquanto obra geosófica e cordial, pois irrompida de um pensar insubordinado emergido junto à condição terrestre e ao coração. Irrupção aqui compreendida como insurreição ontológica: rebeldia contra a hegemonia do pensamento euro-ocidental e dirigida ao cultivo de outros modos de pensar.
Methods of decreasing losses in optical metamaterials
Authors: Jaksic Zoran , Obradov Marko , Jaksic Olga , Isic Goran , Vukovic Slobodan , Radovic Vasiljevic
Published: December 2018

In this work we review methods to decrease the optical absorption losses in
metamaterials. The practical interest for metamaterials is huge, but the
possible applications are severely limited by their high inherent optical
absorption in the metal parts. We consider the possibilities to fabricate
metamaterial with a decreased metal volume fraction, the application of
alternative lower-loss plasmonic materials instead of the customary utilized
noble metals, the use of all-dielectric, high refractive index contrast
subwavelength nanocomposites. Finally, we dedicate our attention to various
methods to optimize the frequency dispersion in metamaterials by changing
their geometry and composition in order to reach lower absorption, which
includes the use of the hypercrystals. The final goal is to widen the range
of different metamaterialbased devices and structures, including those
belonging to transformation optics. Maybe the most important among them is
the fabrication of a novel generation of alloptical or hybrid
optical/electronic integrated circuits that would operate at optical
frequencies and at the same time would offer a packaging density and
complexity of the contemporary integrated circuits, owing to the strong
localization of electromagnetic fields enabled by plasmonics.
Tendencias en la desigualdad de oportunidades educativas en Uruguay
Authors: Cardozo Politi Santiago , Menese Camargo Pablo Andrés
Published: December 2018

En este artículo estudiamos los cambios en la desigualdad de oportunidades educativas (ieo) asociadas a la clase de origen, en el marco de la expansión de la escolarización en Uruguay, para las cohortes nacidas entre 1942 y 1987. Modelamos la ieo sobre i) los logros educativos con base en modelos log-lineales y log-multiplicativos, y ii) sobre las transiciones (Mare models). Nuestros resultados sugieren: i) que la expansión de la escolarización, mayor en las clases bajas e intermedias, no supuso sin embargo una reducción clara de la ieo en términos agregados; ii) de hecho, la ieo se incrementó para las mujeres, especialmente entre las hijas de las clases medias y de las clases trabajadoras, mientras que para los varones, la evidencia es consistente con la hipótesis de ieo persistentes; iii) durante el periodo analizado, las ieo se trasladaron hacia las transiciones educativas más avanzadas.
Uso excesivo de la fuerza policial en la CDMX
Authors: Silva Forné Carlos
Published: December 2018

El presente estudio analiza quejas por violaciones al derecho a la integridad personal recibidas durante cinco años en la Comisión de Derechos Humanos de la Ciudad de México con dos objetivos: en primer lugar, describir diferencias de los casos de abuso policial según su lugar de ocurrencia; en segundo, para conocer, en el caso de los abusos cometidos en situaciones de detención o control a una persona, qué factores aumentan la probabilidad de un abuso grave. Los factores se desprenden de ello y permiten comparar distintas tradiciones teóricas acerca del uso excesivo de la fuerza policial. El resultado muestra cómo la presencia de los factores más consolidados, desde la perspectiva teórica de la amenaza criminal al nivel situacional –la resistencia activa y las situaciones en delitos graves–, aumentan de manera significativa la probabilidad de  que ocurran los abusos policiales graves en la Ciudad de México.
Chicas muertas de Selva Almada. Nuevas formas de la memoria sobre el femicidio en la narrativa argentina
Authors: Cabral María Celeste
Published: December 2018

Los episodios traumáticos del pasado dictatorial ocuparon en la literatura argentina un espacio central. Chicas muertas de Selva Almada inicia el diálogo con ese corpus en dos planos: por un lado señala la invisibilidad de los feminicidios durante el retorno de la democracia. Por otra parte, el texto recupera la pregunta sobre cómo narrar la violencia extrema que –iniciada en el aforismo de Theodor Adorno (1955)– recorre las discusiones en torno a las formas del relato sobre el pasado reciente. Este trabajo explora en el texto de Almada las nuevas memorias sobre el feminicidio que emergen en el campo literario en un contexto de profunda sensibilización social sobre el tema.
Real-Time Biofeedback of Performance to Reduce Braking Forces Associated With Running-Related Injury: An Exploratory Study
Authors: Napier Christopher , MacLean Christopher L. , Maurer Jessica , Taunton Jack E. , Hunt Michael A.
Published: December 2018

Background

The high rate of running-related injury may be associated with increased peak braking forces (PBFs) and vertical loading rates. Gait retraining has been suggested by some experts to be an effective method to reduce loading parameters.

Objectives

To investigate whether PBF could be decreased following an 8-session gait retraining program among a group of female recreational runners and which self-selected kinematic strategies could achieve this decrease.

Methods

In this exploratory study, 12 female recreational runners with high PBFs (greater than 0.27 body weight) completed an 8-session gait retraining program with real-time biofeedback of braking forces over the course of a half-marathon training program. Baseline and follow-up kinetics and kinematics were analyzed with a repeated-measures analysis of variance.

Results

There was an average reduction of 15% in PBF (−0.04 body weight; 95% confidence interval [CI]: −0.07, −0.02 body weight; P = .001; effect size, 0.62), accompanied by a 7% increase in step frequency (11.3 steps per minute; 95% CI: 1.8, 20.9 steps per minute; P = .024; effect size, 0.38) and a 6% decrease in step length (−5.5 cm; 95% CI: −9.9, −1.0 cm; P = .020; effect size, 0.40), from baseline to follow-up.

Conclusion

The gait retraining program significantly reduced the PBF among a group of female recreational runners. This was achieved through a combination of increased step frequency and decreased step length. Furthermore, the modified gait pattern was incorporated into the runners' natural gait pattern by the completion of the program. Based on these results, the outlined gait retraining program should be further investigated to assess whether it may be an effective injury prevention strategy for recreational runners. This study was registered with ClinicalTrials.gov (NCT03302975).

Level of Evidence

Prevention, level 4. J Orthop Sports Phys Ther 2019;49(3):136–144. Epub 7 Dec 2018. doi:10.2519/jospt.2019.8587
Online Bibliographic Products: Theory Issues and the Practice of the Russian State Library and the National Library of Russia
Authors: Levin Grigoriy L.
Published: December 2018

The article highlights the research work “Information and bibliographic activities in the modern electronic environment”, “Electronic bibliographic products in the structure of information resources of Federal and Central regional libraries” carried out by the Scientific research Department of bibliography of the Russian State Library in 2017 — the first half of 2018. The author considers a number of general theoretical and methodological issues: what are the library’s information resources; what is the place of bibliographic resources in their structure; and what is the type-specific structure of bibliographic resources of library, including electronic ones. The important part of the library’s information resources are bibliographic resources, including electronic of two main types (classes): innovative (bibliographic databases, electronic catalogues), and traditional (bibliographic catalogues-inventories, indexes, lists, reviews, etc.). The article presents the results of the comparative analysis of resources of the second type created in the Russian State Library and the National Library of Russia in 2009—2017.

The websites of both libraries contain digital copies and electronic versions of printed bibliographic publications, as well as original bibliographic products (which have no printed analogues). Online bibliographic products have firmly taken their place in the structure of information resources of national libraries, somewhere supplementing them and somewhere replacing the printed format.
Zeolites Fit For A Crown: Probing Host-Guest Interactions with Thermogravimetric Methods
Authors: Sartbaeva Asel , Raithby Paul R. , Castaing Remi , Nearchou Antony
Published: December 2018

Through a combination of thermogravimetry, mass spectrometry and differential thermal analysis, we demonstrate for the first time that all four zeolites show experimental differences in their host-guest interactions with 18C6. In addition, we have estimated the kinetics of 18C6 decomposition, which is a technique that has not been applied to zeolites previously. Using these findings as a toolkit, a more rational use of OSDAs can be utilised to prepare designer zeolites. Furthermore, the new methodologies presented herein can be applied to current zeolites, such as MFI-type zeolites used in the petrochemical industry.
Deleuze sobre a importância do acordo discordante em Kant
Authors: Viegas Susana
Published: December 2018

Apresentamos a leitura deleuziana do papel e do poder da imaginação e do esquematismo no juízo estético segundo Immanuel Kant destacando, em particular, a importância de se pensar um desacordo entre faculdades e de, no limite, afirmarmos a impossibilidade de uma filosofia da arte. Como se dá o processo que liga sensações e conceitos, arte e filosofia? Ao respondermos a esta questão, também esclarecemos a situação peculiar de Kant na filosofia de Gilles Deleuze e a leitura que este faz em A Filosofia Crítica de Kant, publicado em 1963. Teremos como objeto de análise um filme sensorial, To the Wonder/A Essência do Amor (2012), realizado por Terrence Malick.
Hydraulic and Leaf Economics of Woody Plants of the Tropical Environment
Authors: Chagas Maria das Graças Santos das , Pimentel Rejane Magalhães de Mendonça , Silva Luiz Henrique Gonçalves da
Published: December 2018

Leaf photosynthesis and hydraulic traits are closely related to the maintenance of the plants, especially in tropical environments. There is scarce information about the xylem structure and hydraulic efficiency in tropical species, mainly considering the leaf. Environmental changes influence the species performance, conditioning differences of anatomical traits and functional efficiency of xylem cells related to the water flow inside the plant. The hydraulic conductivity and the theoretical leaf-specific conductivity allow estimating the xylem cells flow and inform about the efficiency of the water transport inside the plant. The relation among leaf biometry and anatomic/hydraulic characteristics of the xylem cells of leaves with different stages of growth, of five woody species from the tropical environment, was evaluated. Differences among leaves of different ages and species indicate to be responsible for the anatomical traits variations. The xylem hydraulic traits indicate a greater or smaller efficiency in leaves water transport and are related to the species. The hydraulic and structural differences indicate an adaptation to higher efficiency in water transport in leaves related to the prevailing environmental conditions during the leaf development.
EKSTRAK DAUN SELEDRI (EX-SEL) DALAM KEMASAN EKONOMIS SIAP MINUM UNTUK TERAPI HIPERTENSI
Authors: Donna Baiq Puja , Wijaya Lalu Satria , Syahid Muhammad Abdul , Karine Sri Wulan , Handini Yusika Saftarani
Published: December 2018

Hipertensi merupakan salah satu penyakit dengan tingkat mortalitasnya sangat tinggi di seluruh dunia. WHO tahun 2010 menjelaskan bahwa hipertensi merupakan penyebab kematian nomor satu di dunia. Menurut Riskesdas RI tahun 2013 tingkat prevalensi hipertensi di Indonesia diperoleh sekitar 25,8%. Perlu diciptakan sebuah media pengobatan untuk mencegah terjadinya hipertensi yang tidak terkontrol, salah satunya bisa dengan memanfaatkan tanaman Seledri. Di Indonesia tanaman seledri sudah lama dikenal sebagai tanaman obat tradisional yang dipercaya memiliki khasiat untuk menurunkan tekanan darah. Oleh karena itu,  tujuan kegiatan ini adalah untuk menghasilkan sebuah produk baru dari olahan daun seledri yang dapat digunakan sebagai terapi hipertensi. Metode pelaksanaan kegiatan terdapat 4 tahapan yang digunakan dalam melakukan pengembangan kegiatan, yakni tahap persiapan, promosi, pemasaran, dan evaluasi. Hasil kegiatan menunjukkan bahwa minuman ekstrak seledri yang dihasilkan dari olahan daun seledri memiliki efek yang dapat menurunkan dan mengontrol tekanan darah dari penderita hipertensi. Ekstrak daun seledri sudah dipasarkan di daerah Mataram dan sekitarnya.
PENGARUH PENGGUNAAN PROBIOTIK YANG DIFERMENTASI DENGAN SUMBER KARBON YANG BERBEDA TERHADAP PERTUMBUHAN UDANG VANNAME (Litopenaeus vannamei)
Authors: Citria Ika , Abidin Zaenal , Astriana Baiq Hilda
Published: December 2018

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan karbon yang berbeda dalam perbanyakan probiotik terhadap jumlah koloni bakteri, dan aplikasinya dalam pemeliharaan udang vanammei (Litopenaeus vannamei).  Penelitian ini dilakukan di Balai Pengembangan Budidaya Perikanan Pantai (BPBPP) Sekotong, Lombok Barat. Sumber karbon yang digunakan dalam fermentesi bakteri probiotik adalah tapioka, dedak halus, dan jagung. Probiotik hasil perbanyakan kemudian diujikan ke udang post larva 20 untuk mengetahui tingkat pertumbuhan udang yang diberikan probiotik. Hasil penelitian menunjukkan bahwa jumlah koloni bakteri mengalami peningkatan yang lebih tinggi dari kontrol pada masing-masing media fermentasi yang dihitung pada hari ke-7dan hari ke 30. Penggunaan tapioka sebagai sumber karbon menghasilkan jumlah bakteri paling banyak yaitu  3.69x1011 CFU/ml  dibandingkan dengan sumber karbon dari dedak dan jagung.  Hasil uji penggunaan probiotik tersebut ke udang menunjukkan bahwa probiotik dengan sumber karbon tapioka menghasilkan pertumbuhan harian udang tertinggi yaitu 4,36% dibandingkan dengan dua probiotik lainnya.
Respuesta de fresa cv. Albión a dosis crecientes de zinc
Authors: López-Herrera Amelia , Castillo-González Ana María , Trejo-Téllez Libia Iris , Avitia-García Edilberto , Valdez-Aguilar Luis Alonso
Published: December 2018

El Zn es un micronutrimento que tiene influencia importante en el crecimiento, rendimiento y calidad de los cultivos. El objetivo del presente trabajo fue evaluar el efecto de dosis crecientes de Zn en la solución nutritiva en el crecimiento, rendimiento y calidad del fruto en fresa cv. Albion. Para lo cual se establecieron plantas de fresa en macetas de 2.5 L con tezontle, en un sistema hidropónico abierto. Los tratamientos fueron: testigo (sin aplicación de Zn), 1, 2.5, 5, 7.5, 10, 15, 20, 30 y 40 µmol L-1 de Zn (ZnSO4 7H2O) en la solución nutritiva. El rendimiento se incrementó 151, 161 y 134% con las dosis de 5, 7.5 y 10 µmol L-1, respectivamente. Con la dosis de 7.5 µmol L-1 se incrementó 60% la biomasa de la planta, 93% el peso fresco de los frutos y 24% su firmeza. Con las dosis desde 2.5 hasta 15 µmol L-1 se incrementaron los sólidos solubles totales (SST), acidez titulable (AT), la relación SST/AT y la concentración de azúcares solubles totales. La mejor concentración foliar de Zn (de suficiencia) (22 mg kg -1 de materia seca) se registró con 7.5 µmol L-1. Por lo que se sugiere usar las dosis de Zn entre 5 y 15 µmol L-1 en la solución nutritiva para cubrir satisfactoriamente el requerimiento de este cultivar.
An Application of Software Engineering for Reading Linear-B Script
Authors: Papakitsos Evangelos C. , Kontogianni Argyro , Papamichail Chrysanthi , Kenanidis Ioannis K.
Published: December 2018

Linear-B script has been studied for sixty years since its decipherment. The laborious efforts of the scholars have revealed many linguistic aspects of the oldest known form of Greek (i.e., Mycenaean/Danaic Greek), thus allowing the study of this Indo-European language and its dynamics for thirty-five centuries. In addition, linguistic phenomena closer to the roots of Indo-European languages can be also studied. Yet, the limited usage of Linear-B script, merely for keeping records, and its incompatibility to the Greek phonotactics causes misinterpretations of various kinds. The study of Linear-B was not supported till recently by interactive software tools that would facilitate both research and training. Especially for Greek speakers, the resources are even more limited. This paper presents the development of an interactive software system for the study, learning and researching of Linear-B by Greek speakers. This software system is also suggested as a model for the interpretation of other archaic languages.
ŞEHİR İÇİ PATLATMALI KAZI ÇALIŞMALARINDA ÇEVRESEL TİTREŞİM LİMİTLERİNE GÖRE PATLATMA TASARIMI
Authors: Karakuş Doğan , Öngen Tuğçe , Özdoğan Mehmet Volkan , Yenice Hayati , Deliormanlı Ahmet Hamdi , İkiz Utku
Published: December 2018

Günümüzde kaya kütlelerinin parçalanarak taşınabilir duruma getirilmesinde patlayıcı maddelerve patlatma teknolojisi kaçınılmaz olarak uygulanmaktadır. Madencilik çalışmalarında büyükboyutlu kaya kütlelerinin kazılmasında yaygın olarak kullanılan patlatma teknolojisi aynı zamandaşehir içi ve şehir dışı bölgelerde alan düzeltme amacıyla uygulanmaktadır. Bu çalışmada İzmirBayraklı bölgesinde yapılması planlanan Kent Hastanesi projesinde alan düzeltme amaçlıyaklaşık 3 milyon metreküp patlatmalı kayaç kazısı sırasında, patlatmaların neden olacağıçevresel titreşim seviyesinin proje alanı yakınındaki Bayraklı Tünelleri ve Laka Köyü yerleşimbirimlerini etkilememesine yönelik patlatma tasarımı aşamaları tanıtılmıştır. Bayraklı tünelleriyapısı çevresel titreşim seviyesi limit değeri esas alınarak inşaat alanı bölgelere ayrılmış ve anlıkpatlayıcı miktarına bağlı delik boyları belirlenmiştir.
AÇIK İŞLETMELERDE DÖKÜM ALANLARI DÜZENLEME VE AĞAÇLANDIRMA ÇALIŞMALARI: TUTLUCA MANYEZİT AÇIK İŞLETMESİ
Authors: Kundak Ece , Akdaş Hürriyet
Published: December 2018

Bu çalışma, Magnesit Anonim Şirketi’ne (MAŞ) ait Tutluca Manyezit Açık İşletmesi çevresindeoluşturulan harmanların doğaya yeniden kazandırma kapsamında yapılan düzenlemeleri veağaçlandırma çalışmalarını içermektedir. Bu ağaçlandırma ve düzenleme çalışmaları 1994yılından beri sistematik olarak yapılmaktadır. Bu bölgede, bugüne kadar, planlı 43 farklı alandüzenlenerek ağaçlandırılmıştır. Son on yıldır bu faaliyet, kamu kurumlarının katılımı ileağaçlandırma bayramına dönüştürülmüştür. Bir yandan manyezit üretim faaliyetleri devamederken, diğer yandan da her yıl doğaya yeniden kazandırma kapsamında yapılan düzenlemelerile otsu bitkilerin geliştiği ve doğada yaşayan canlıların yeni oluşturulan bölgelerde yaşamayabaşladıkları gözlemlenmektedir.
DÜŞEY KAYAÇ KESME SETİ İLE KOLLU GALERİ AÇMA MAKİNESİ PERFORMANS TAHMİNİ: BİR ÖRNEK UYGULAMA
Authors: Yaşar Serdar , Yılmaz Ali Osman
Published: December 2018

Kollu galeri açma makineleri madencilik ve tünelcilik sektöründe sıklıkla kullanılan kazımakinelerindendir. Diğer kazı makineleri gibi, kazı yapılacak formasyona uygun olarakseçilmeleri gerekmektedir. İlave olarak, formasyonda gerçekleştirecekleri kazı hızlarının projesafhasında belirlenmesi gerekmektedir. Bu amaç için geliştirilen çeşitli yöntemler bulunmaktadır.Bu yöntemlerden en temsili yöntem olarak kabul edileni kaya kesme deneyleridir. En kesinyöntemler olmalarına rağmen, az sayıda araştırma merkezinde bulunmaları sebebiyle kullanımıyaygınlaşamamaktadır. Bundan dolayı, halihazırda bulunan kaya kesme deneylerine alternatifolabilecek yeni düzeneklere ihtiyaç vardır.Bu amaçla, hemen hemen tüm kaya mekaniği laboratuvarlarında bulunan hidrolik eğilmepreslerine bir eklenti olarak geliştirilen taşınabilir ve seri üretime uygun bir deney düzeneğiolarak getirilen düşey kayaç kesme seti (DKKS) tanıtılmıştır. Çalışma kapsamında, çeşitlimagmatik kayaç numuneleri üzerinde konik keskiler ile etkileşimli ve etkileşimsiz kaya kesmedeneyleri gerçekleştirilmiştir ve DKKS ile tam boyutlu kesme deneylerinin gerçekleştirilebileceğigösterilmiştir. Ardından, bir yeraltı soğuk hava deposunda çalışan bir kollu galeri açmamakinesinin kazı hızları DKKS’de yapılan kaya kesme deneyleri ile tahmin edilmeye çalışılmıştır.Sonuç olarak, bu sahada çalışan makinenin net kazı hızı DKKS ile gerçeğe yakın olarak tahminedilmiştir.
TÜRKİYE MADENCİLİK SEKTÖRÜNDE İŞ KAZALARININ İSTATİSTİKSEL ANALİZİ
Authors: Bayraktar Beril , Uyguçgil Hakan , Konuk Adnan
Published: December 2018

Ülkemizde iş kazaları bütün işkollarında görülmesine rağmen, diğer işkolları ile karşılaştırıldığında,iş kazaları sonrası ölüm oranları yüksekliği nedeniyle madencilik işkolu dikkat çekici birkonumdadır. Her ne kadar çalışanlar eğitilse ve güvenlik önlemleri alınsa da, maden ocaklarındamekanize üretim yerine emek yoğun çalışılması nedeniyle, madencilikte ölümlü iş kazası sıklığıoldukça yüksektir. Bu çalışmada, 2002-2015 yılları arasında Sosyal Güvenlik Kurumu (SGK)istatistik yıllıklarından elde edilen iş kazası verileri istatistiksel olarak incelenmiş, madenciliksektörü ile diğer sektörlerin kaza oranları karşılaştırılmıştır. Analizler sonucunda Türkiye’demadencilik sektöründe meydana gelen iş kazalarının önceki yıllarda ve günümüzde yapılan yasaldüzenlemelere rağmen azalmadığı, aksine çalışan sayısı başına düşen kaza ve ölüm oranlarınındiğer sektörlerle karşılaştırıldığında daha yüksek olduğu belirlenmiştir. Yapılan çalışmasonucunda, madencilik sektöründe küçük ölçekli madencilikten vazgeçilmesi, madenciliktemekanizasyon oranının arttırılması, madenciliğe özgü önlemlerin alınması ve denetimlerinyapılması gerekliliği ortaya çıkmıştır.
AÇIK OCAK İŞLETMELERINDE İŞ GÜVENLIĞI UYGULAMASI: ÖRNEK OCAK ÇALIŞMASI
Authors: Şafak Recep Erdi , Şensöğüt Cem , Kasap Yaşar
Published: December 2018

Dünya nüfusuna paralel olarak, insanoğlunun daha kaliteli yaşama olan talebinin artması,hammadde ve mamul maddelerin üretiminin artmasına neden olmuştur. Bilindiği üzere pekçok hammadde, yeraltı ve yerüstü kaynaklarının madencilik aktiviteleri ile kazanımı sonucuelde edilmektedir. Üretimin sayısal olarak büyük bir kısmı, açık işletme madenciliği ilegerçekleştirilmektedir. Üretim esnasında iş sağlığı ve güvenliği açısından önemli risk ve tehlikelerile karşı karşıya kalındığından dolayı kaza öncesi önlem alınmasına yönelik yaklaşımlar ortayakonularak çalışan işçilerin kazalanma riskinin minimuma indirilmesi gerekmektedir. Bu çalışmadaManyezit A.Ş (Eskişehir)’ye bağlı açık ocak işletmesindeki madencilik faaliyetleri Çeklist Metoduve L Tipi Risk Değerlendirme Karar Matrisi Yöntemi ile irdelenmiş, risk teşkil eden durumlarınkabul edilebilir seviyeye indirilebilmesi için alınması gereken önlemler belirlenmiştir.
TRAVERTENLERDE KAPİLER SU EMMENİN TANIMLANMASI VE SINIFLANDIRILMASI
Authors: Çobanoğlu İbrahim , Çelik Sefer Beran
Published: December 2018

Kapilarite kavramı özellikle atmosferik koşullar sayesinde nemden etkilenebilecek doğal yapıtaşlarıiçin önem taşımaktadır. Travertenler için kapiler su emme değeri hem iç ve hem de dış mekankullanımlarda önem taşıyan bir parametre olarak deneysel olarak belirlenmektedir. Bu anlamdadoğal olarak gözenekli bir yapıya sahip olan travertenler karbonatlı diğer doğaltaşlara göre suyadaha hassas doğal malzemelerdir. Suyla temas halinde yüksek kapiler su emme potansiyelinesahip doğaltaşlar atmosferik koşullardan daha fazla etkilenmektedirler. Genel su emme kavramıele alındığında, hem ağırlıkça su emme ve hacimce su emme ve hem de kapiler yolla su emmeparametrelerinin birbirleriyle yakın ilişkide olabilecekleri düşünülmektedir. Bu parametre ayrıcaCE belgelendirmeleri kapsamında hem Avrupa ülkelerinde ve hem de bu ülkelere ihraç yapanülkelerde, belgelendirmeye esas testler içinde yer almaktadır. Bu amaçla Avrupa normundanuyarlanan TS EN 1925 deney standardı 2000 yılından beri ülkemizde de kullanılmaktadır. Buçalışma, kapiler su emmenin gözenekli bir doğal yapıtaşı olan travertenler üzerinde elde edilmişsonuçlarını içermektedir. Elde edilen veriler kullanılarak travertenler için geçerli olabilecek 4kategoriden oluşan bir kapiler su emme sınıflaması da bu çalışma kapsamında önerilmiştir.
The Effect of Learning Model Survey, Question, Read, Recite Review (SQ3R) and Critical Thingking Ability to Senior High School Students’ Learning Result
Authors: Fahmawati Fahriyah , Rusdi Rusdi , Komala Ratna
Published: December 2018

Developing study in 21 century, the students must have a good skill which can support in developing era. One of the skills is critical thinking. The students must have the competence which can solve the problem faced it for instance environment pollution problem. The problem is one of parts from Biology with collaboration study model  of SQ3R that has superior for cooperation between  inactive and active students , the hope can give big contribute for the students can solve the problem. The Quasi experiment uses Anava two direction (2x2) Factorial. The research is done at SMAN 1 N Tambun Utara on September-October 2017. Data of the result research shows normal point and homogeny (P> 0,05) with sample 140.. The result of research uses the Anava experiment two direction can be gotten P = 0,000 ,it means P < 0,05 (reject Ho). So the summary (1) There can be the effect of the study model of SQ3R to The result of study. (2) There can be the effect of critical thinking to the result of study. (3) There can be interaction between SQ3R and critical thinking to the result of study.

 

Keywords: Critical thinking, the result of study of environment pollution, SQ3R