bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Convenient Synthesis and Biological Profile of 5‐Amino‐Substituted 1,2,4‐Oxadiazole Derivatives.
Authors: Ispikoudi Maria , Amvrazis Michalis , Kontogiorgis Christos , Koumbis Alexandros E. , Litinas Konstantinos E. , Hadjipavlou‐Litina Dimitra , Fylaktakidou Konstantina C.
Published: March 2011

Reaction of amidoximes (I) and (VI) with carbodiimides (II) and (VII) affords the oxadiazoles (III) and (VIII) in a straightforward manner.
ChemInform Abstract: A Practical Synthesis of 5‐Aroyl‐1‐aryltetrazoles Using an Ugi‐Like 4‐Component Reaction Followed by a Biomimetic Transamination.
Authors: Giustiniano Mariateresa , Pirali Tracey , Massarotti Alberto , Biletta Beatrice , Novellino Ettore , Campiglia Pietro , Sorba Giovanni , Tron Gian Cesare
Published: March 2011

Four‐component reaction of aromatic aldehydes, aromatic isonitriles, benzylamine, and TmsN3 followed by subsequent transformation of the resulting thiazoles (IV) offers a straightforward synthesis of the title compounds (VI).
ChemInform Abstract: Efficient One‐Pot Synthesis of 1,3‐Diaryl‐3H‐benzo[f]chromenes Using Ferric Hydrogensulfate.
Authors: Eshghi Hossein , Zohuri Gholam Hossein , Damavandi Saman , Vakili Mohammad
Published: March 2011

A simple and efficient approach for the synthesis of the title benzochromenes via Fe(HSO4)3‐catalyzed three‐component condensation of naphthols with phenylacetylene and aromatic aldehydes is described.
ChemInform Abstract: Synthesis, Biological Activity, and Evaluation of the Mode of Action of Novel Antitubercular Benzofurobenzopyrans Substituted on A Ring.
Authors: Michel Sylvie , et al. et al.
Published: March 2011

Benzofurobenzopyrans such as (VIII) and (X), bearing halogen, hydroxy, and methoxy substituents on the A‐ring are synthesized in satisfactory yields by means of a novel access allowing substitutions at all positions of the A‐ring.
ChemInform Abstract: A Convenient Entry to 3‐Methylidenechroman‐2‐ones and 2‐Methylidenedihydrobenzochromen‐3‐ones.
Authors: Modranka Jakub , Albrecht Anna , Janecki Tomasz
Published: March 2011

An efficient route to biologically important title chromane derivatives (VII) and (XI) is developed.
ChemInform Abstract: Regioselective Control of 1,2‐ versus 1,4‐Addition in Organocatalytic Reactions of o‐Hydroxycinnamaldehydes with Organoboronic Acids.
Authors: Choi Kwang‐Su , Kim Sung‐Gon
Published: March 2011

Different reaction conditions result in highly selective 1,4‐addition to produce 4‐substituted chroman‐2‐ols or 1,2‐addition with formation of 2‐substituted 2H‐chromenes.
ChemInform Abstract: An Efficient One‐Step Hantzsch Multicomponent Synthesis of 1,4‐Dihydropyridines via a Wells‐Dawson Heteropolyacid Catalyst under Solvent‐Free Conditions.
Authors: Sathicq Angel G. , Romanelli Gustavo P. , Ponzinibbio Agustin , Baronetti Graciela T. , Thomas Horacio J.
Published: March 2011

Wells—Dawson heteropolyacid (H6P2W18O62·24H2 O) is shown to be an excellent catalyst for the Hantzsch 1,4‐dihydropyridine synthesis.
ChemInform Abstract: A New One‐Pot Solvent‐Free Synthesis of Pyridinyl Tosylates via Diazotization of Aminopyridines.
Authors: Tretyakov Alexey N. , Krasnokutskaya Elena A. , Gorlushko Dmitry A. , Ogorodnikov Vladimir D. , Filimonov Victor D.
Published: March 2011

Substituted aminopyridines can be directly transformed into the corresponding pyridinyl tosylates by sequential diazotation and tosylation of the substrates under solvent‐free conditions.
ChemInform Abstract: Efficient Synthesis of 6‐(Hetero)arylthieno[3,2‐b]pyridines by Suzuki—Miyaura Coupling. Evaluation of Growth Inhibition on Human Tumor Cell Lines, SARs and Effects on the Cell Cycle.
Authors: Queiroz Maria‐Joao R. P. , Calhelha Ricardo C. , Vale‐Silva Luis A. , Pinto Eugenia , Lima Raquel T. , Vasconcelos M. Helena
Published: March 2011

Cross‐coupling reactions between aminothienopyridine derivatives (I) and potassium trifluoroborates (II) or hetaryl pinacolborane esters (IV) under general conditions afford the title compounds (III) and (V) in good to very good yields.
ChemInform Abstract: Calcium‐Promoted Pictet—Spengler Reactions of Ketones and Aldehydes.
Authors: Vanden Eynden Matthew J. , Kunchithapatham Kamala , Stambuli James P.
Published: March 2011

The calcium compound as an efficient catalyst allows direct and convenient formation of a wide range of tetrahydroisoquinolines in good to high yields.
ChemInform Abstract: Preparation of New Nitrogen‐Bridged Heterocycles. Part 72. A New Approach to 1‐Acyl‐3‐(substituted methylthio)thieno[3′,4′:4,5]imidazo[1,5‐a]pyridine Derivatives.
Authors: Kakehi Akikazu , Suga Hiroyuki , Okumura Yukihisa , Itoh Kennosuke , Kobayashi Kouji , Aikawa Yoshihiro , Misawa Kotaro
Published: March 2011

The alkylation of thiolates (IV) followed by base‐mediated cyclization gives rise to desired thienoimidazopyridines such as (VI) and (VII) (87 examples).
ChemInform Abstract: Thiosalicylic Acid Catalyzed Multicomponent Reactions: Microwave‐Assisted Synthesis of New Extended Angular Fused Azaheterocycles.
Authors: Zhang Ge , Ma Ning , Jiang Bo , Shi Feng , Tu Shu‐Jiang
Published: March 2011

A new variant concerning the synthesis of title compounds with luminescent properties is developed using thiosalicylic acid as promotor.
ChemInform Abstract: A One‐Pot Domino Reaction for the Synthesis of 3‐Arylindolizines from Pyridines, Benzyl Halides, and Dihalide‐Substituted Electron‐Deficient Alkenes.
Authors: Hu Huayou , Shi Kunbo , Hou Rongrong , Zhang Zaichao , Zhu Yulan , Zhou Jianfeng
Published: March 2011

A regioselective approach becomes possible by a general 1,3‐dipolar cycloaddition strategy.
ChemInform Abstract: Design and Synthesis of Novel Tetrahydro‐2H‐pyrano[3,2‐c]pyridazin‐3(6H)‐one Derivatives as Potential Anticancer Agents.
Authors: Al‐Tel Taleb H.
Published: March 2011

The polyfunctional title compounds (VII) are produced by a reaction sequence in which the oxidative cyclization is the basic core.
ChemInform Abstract: Antimicrobial, Antitumor and 5α‐Reductase Inhibitor Activities of Some Hydrazonoyl Substituted Pyrimidinones.
Authors: Edrees Mastoura M. , Farghaly Thoraya A. , El‐Hag Fatma A. A. , Abdalla Mohamed M.
Published: March 2011

Coupling the diazonium salt of aniline derivatives with (chlorobenzoylmethylene)methylpyrimidinone furnishes the arylhydrazono derivatives (III) in good yields.
ChemInform Abstract: One‐Pot Synthesis of 7‐Aryl‐11,12‐dihydrobenzo[h]pyrimido[4,5‐b]quinoline‐8,10(7H,9H)‐diones via Three‐Component Reaction in Ionic Liquid.
Authors: Guo Hong Yun , Yu Yi
Published: March 2011

The methodology described provides several advantages such as easy work‐up, high yields and an environmentally benign procedure.
ChemInform Abstract: Antimony Trichloride Catalyzed Three‐Component Reaction of Urea, Aldehydes and Cyclic Enol Ethers: A Novel Route to 4‐Arylhexahydrofuro[2,3‐d]pyrimidin‐2(3H)‐ones.
Authors: Bhattacharya R. N. , Kundu Pradip , Maiti Gourhari
Published: March 2011

4‐Substituted furano‐ and pyranopyrimidinones are prepared stereoselectively in high yields using a simple one‐pot procedure.
ChemInform Abstract: Synthesis, Antitrichinnellosis and Antiprotozoal Activity of Some Novel Thieno[2,3‐d]pyrimidin‐4(3H)‐ones Containing Benzimidazole Ring.
Authors: Mavrova Anelia Ts. , Vuchev Dimitar , Anichina Kameliya , Vassilev Nikolay
Published: March 2011

Nucleophilic substitution reactions between thienopyrimidinones (III) and substituted benzimidazolylthiols (IV) result in the formation of compounds (V) while interaction of (III) with unsubstituted benzimidazole (VI) in the presence of tetrabutylammonium bromide and potassium carbonate affords higher yields of the products (VII) than in the presence of sodium hydroxide.
ChemInform Abstract: Synthesis and Characterization of 1,3‐Dihydro‐benzo[b][1,4]diazepin‐2‐one Derivatives. Part 4. In vivo Active Potent and Selective Non‐competitive Metabotropic Glutamate Receptor 2/3 Antagonists.
Authors: Woltering Thomas J. , Wichmann Juergen , Goetschi Erwin , Knoflach Frederic , Ballard Theresa M. , Huwyler Joerg , Gatti Silvia
Published: March 2011

A variety of the title benzodiazepine derivatives (I) are synthesized and evaluated as metabotropic glutamate receptor antagonists.
ChemInform Abstract: An Easy Assembled, Click‐Generated Macrocyclic Chromoionophores as Mercury(II) Sensors.
Authors: Lu Yun‐Guo , Li Zao‐Ying , Lee Albert W. M. , Chan Wing‐Hong
Published: March 2011

Macrocyclic chromoionophores of type (V) are prepared.
ChemInform Abstract: Reactions of Nitroxides. Part 9. Reactive (Thio)phosphoryl Monochlorides Bearing a Nitroxyl Moiety and Nitroxyl Derivatives of Coumarin.
Authors: Huras Bogumila , Zakrzewski Jerzy , Krawczyk Maria
Published: March 2011

Phosphorylated coumarin derivatives of type (V) bearing a nitroxyl moiety show antifungal activities.
ChemInform Abstract: Catalytic Enantioselective Ring‐Opening Reaction of meso‐Epoxides with ArSeH Using a (Salen)Ti(IV) Complex.
Authors: Yang Minghua , Pei Ji , Sun Jiangtao , Yuan Fang , Zhu Chengjian
Published: March 2011

Optimum reaction conditions are examined for the enantioselective ring opening of epoxides with arylselenols using a (salen)Ti(IV) complex.
ChemInform Abstract: Oleanane‐Type Triterpenoids from Panax stipuleanatus and Their Anticancer Activities.
Authors: Liang Chun , Ding Yan , Nguyen Huu Tung , Kim Jeong‐Ah , Boo Hye‐Jin , Kang Hee‐Kyoung , Nguyen Mahn Cuong , Kim Young Ho
Published: March 2011

Spinasaporin A methyl ester (I) is isolated together with ten known oleanane‐type triterpenoids from the title species.
ChemInform Abstract: Synthesis of Novel α‐Santonin Derivatives as Potential Cytotoxic Agents.
Authors: Arantes Francisco F. P. , Barbosa Luiz C. A. , Maltha Celia R. A. , Demuner Antonio J. , da Costa Patricia Marcal , Ferreira Jose R. O. , Costa‐Lotufo Leticia V. , Moraes Manoel O. , Pessoa Claudia
Published: March 2011

A series of novel sesquiterpenes is prepared starting from the known α‐santonin derived derivatives (I) and (VII).
ChemInform Abstract: The Synthesis of Phenylalanine‐Derived C5‐Substituted Rhodanines and Their Activity Against Selected Methicillin‐Resistant Staphylococcus aureus (MRSA) Strains.
Authors: Hardej Diane , Ashby Charles R. Jr. , Khadtare Nikhil S. , Kulkarni Shridhar S. , Singh Satyakam , Talele Tanaji T.
Published: March 2011

Glycine and phenylalanine‐derived rhodanine analogues are prepared.
ChemInform Abstract: La(OTf)3: An Efficient Promoter for Thioglycoside Activation in Conjunction with N‐Iodosuccinimide.
Authors: Mukherjee Somnath , Mukhopadhyay Balaram
Published: March 2011

Upon activation with the novel catalyst system, glycosylation of a range of thioglycoside donors with various glycosyl acceptors furnishes stereoselectively the disaccharide products in high yields.
ChemInform Abstract: Carbohydrate Building Blocks in the Ugi Three‐Component Coupling Reaction: Convenient Annulation of Iminosugars on Imidazoles.
Authors: Rai Vijai K. , Singh Santosh , Singh Pankaj , Yadav Lal Dhar S.
Published: March 2011

A new version is developed using D‐xylose or D‐glucose as aldehyde reaction component to yield annulated imidazoles.
ChemInform Abstract: Microwave‐Irradiated C6‐Functionalization of 6‐Chloropurine Nucleosides with Various Mild Nucleophiles under Solvent‐Free Conditions.
Authors: Guo Hai‐Ming , Xin Peng‐Yang , Niu Hong‐Ying , Wang Dong‐Chao , Jiang Yi , Qu Gui‐Rong
Published: March 2011

The general and rapid method avoids strong alkaline nucleophiles and the need for efficient leaving groups.
ChemInform Abstract: Efficient Synthesis of Natural Polyphenolic Stilbenes: Resveratrol, Piceatannol and Oxyresveratrol.
Authors: Sun Hong‐Yi , Xiao Chun‐Fen , Cai Yu‐Chen , Chen Yu , Wei Wen , Liu Xian‐Ke , Lv Ze‐Liang , Zou Yong
Published: March 2011

The Perkin condensation of acid (IV) with aldehyde (V) followed by a copper‐promoted decarboxylation and subsequent demethylation‐isomerization reaction gives rise to resveratrol (VIIIa).
ChemInform Abstract: Development of Heterogeneous Olympic Medal Metal Nanoparticle Catalysts for Environmentally Benign Molecular Transformations Based on the Surface Properties of Hydrotalcite
Authors: Kaneda Kiyotomi , Mitsudome Takato , Mizugaki Tomoo , Jitsukawa Koichiro
Published: March 2011

Review: 74 refs.
ChemInform Abstract: Arsenic Chemistry in Soils and Sediments
Authors: Fendorf Scott , Nico Peter S. , Kocar Benjamin D. , Masue Yoko , Tufano Katharine J.
Published: March 2011

Review: 105 refs.
ChemInform Abstract: Luminescent Semiconductiors
Authors: Wickleder Claudia
Published: March 2011

Review: 7 refs.
ChemInform Abstract: Metal‐Assisted Chemical Etching of Silicon
Authors: Huang Zhipeng , Geyer Nadine , Werner Peter , de Boor Johannes , Goesele Ulrich
Published: March 2011

Review: 121 refs.
ChemInform Abstract: Binuclear Ladder‐Type Complexes as Building Blocks for the Synthesis of Novel Polynuclear Systems
Authors: Orlova T. Yu. , Nekrasov Yu. S.
Published: March 2011

Review: 28 refs.
ChemInform Abstract: Isomers in the Chemistry of Iron Coordination Compounds
Authors: Melnik Milan , Kohutova Maria
Published: March 2011

Review: 111 refs.
ChemInform Abstract: A Decade of Octacyanides in Polynuclear Molecular Materials
Authors: Sieklucka Barbara , Podgajny Robert , Korzeniak Tomasz , Nowicka Beata , Pinkowicz Dawid , Koziel Marcin
Published: March 2011

Review: about 170 refs.
ChemInform Abstract: Symmetric SES‐ and Hybrid SEY‐Pincer Complexes with Thioamide and Thiophosphoryl Coordinating Arms
Authors: Odinets Irina L. , Aleksanyan Diana V. , Kozlov Vladimir A.
Published: March 2011

Review: Pd, Pt, Re, and Sn complexes; 44 refs.
ChemInform Abstract: Platinum Complexes of Five‐ and Six‐Membered P‐Heterocycles as Potential Catalysts
Authors: Keglevich Gyoergy , Kollar Laszlo
Published: March 2011

Review: 53 refs.
ChemInform Abstract: Palladium‐Catalyzed Aminocarbonylation of Iodoalkenes and Iodoarenes
Authors: Skoda‐Foeldes Rita , Kollar Laszlo
Published: March 2011

Review: 39 refs.
ChemInform Abstract: Synthetic Chemistry of Acenes and Heteroacenes
Authors: Qu Hemi , Chi Chunyan
Published: March 2011

Review: 206 refs.
ChemInform Abstract: Recent Progress on the Studies of the True Catalyst in the Heck Reaction with Supported Pd Particles
Authors: Huang Lin , Wong Pui Kwan
Published: March 2011

Review: 98 refs.
ChemInform Abstract: The Mechanism of the Modified Ullmann Reaction
Authors: Sperotto Elena , van Klink Gerard P. M. , van Koten Gerard , de Vries Johannes G.
Published: March 2011

Review: 150 refs.
ChemInform Abstract: Porous Organic Molecules
Authors: Holst James R. , Trewin Abbie , Cooper Andrew I.
Published: March 2011

Review: 52 refs.
ChemInform Abstract: Formation of a Four‐Membered Ring
Authors: Hoffmann Norbert
Published: March 2011

Review: 158 refs.
ChemInform Abstract: Asymmetric Hydrogenation of Minimally Functionalized Terminal Olefins: An Alternative Sustainable and Direct Strategy for Preparing Enantioenriched Hydrocarbons.
Authors: Pamies Oscar , Andersson Pher G. , Dieguez Montserrat
Published: March 2011

Review: 56 refs.
ChemInform Abstract: Borylnitrenes: Electrophilic Reactive Intermediates with High Reactivity Towards C—H Bonds.
Authors: Bettinger Holger F. , Filthaus Matthias
Published: March 2011

Review: 109 refs.
ChemInform Abstract: Metal‐Mediated Oxidative Cross‐Coupling of Terminal Alkynes: A Promising Strategy for Alkyne Synthesis.
Authors: Shao Zhihui , Peng Fangzhi
Published: March 2011

Review: 24 refs.
ChemInform Abstract: Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910.
Authors: Christmann Mathias
Published: March 2011

Review: 19 refs.
ChemInform Abstract: Change of Direction: Enantioselective CuH‐Catalyzed 1,2‐Reduction of α,β‐Unsaturated Ketones.
Authors: Malkov Andrei V.
Published: March 2011

Review: 17 refs.
ChemInform Abstract: Salen‐Complex‐Mediated Formation of Cyclic Carbonates by Cycloadddition of CO2 to Epoxides.
Authors: Decortes Antonello , Castilla Ana M. , Kleij Arjan W.
Published: March 2011

Review: ca. 100 refs.
ChemInform Abstract: Synthesis and Bioactivity of Carbohydrate Derivatives of Indigo, Its Isomers and Heteroanalogues
Authors: Karapetyan Gnuni , Chakrabarty Kuheli , Hein Martin , Langer Peter
Published: March 2011

Review: 61 refs.
ChemInform Abstract: Partial Agonists and Subunit Selectivity at NMDA Receptors.
Authors: Risgaard Rune , Hansen Kasper B. , Clausen Rasmus P.
Published: March 2011

Review: 31 refs.
ChemInform Abstract: Regulation of Cardiovascular Functions by the Phosphorylation of TRPC Channels
Authors: Nishida Motohiro , Saiki Shota , Kitajima Naoyuki , Nakaya Michio , Sato Yoji , Kurose Hitoshi
Published: March 2011

Review: 21 refs.
ChemInform Abstract: Research on Search of the Carotenoid‐Producing Microorganisms in Marine Area and the Improvement of Production Ratio
Authors: Sakagami Yoshikazu , Sumiya Yasuji , Komemushi Sadawo
Published: March 2011

Review: 8 refs.
ChemInform Abstract: Microbe‐Inspired System Enzymology of Vitamin B12 Metabolism
Authors: Toraya Tetsuo
Published: March 2011

Review: 28 refs.
ChemInform Abstract: Colloidal Microcapsules: Self‐Assembly of Nanoparticles at the Liquid—Liquid Interface.
Authors: Patra Debabrata , Sanyal Amitav , Rotello Vincent M.
Published: March 2011

Review: 71 refs.
ChemInform Abstract: Artificial Light‐Harvesting Antennae: Electronic Energy Transfer by Way of Molecular Funnels
Authors: Ziessel Raymond , Harriman Anthony
Published: March 2011

Review: recent developments in the synthesis and spectroscopic characterization of boron dipyrromethene dyes; 110 refs.
ChemInform Abstract: New Technologies for Immunotherapy Against Cancer: Development of Cell Expansion Technology and Viruses as Immune Boosters
Authors: Harada Yui , Yonemitsu Yoshikazu
Published: March 2011

Review: 15 refs.
ChemInform Abstract: Differentiation of Functional Cells from iPS Cells by Efficient Gene Transfer.
Authors: Kawabata Kenji , Tashiro Katsuhisa , Mizuguchi Hiroyuki
Published: March 2011

Review: [16 refs.]
ChemInform Abstract: Analysis and Supplement with the Mechanism of Electrosynthesizing Benzofuran Derivatives
Authors: Li Yunhui , Zhou Jie , Gao Xiuxia , Wang Feifei , Wang Yupeng
Published: March 2011

Review: 15 refs.
ChemInform Abstract: Insights into Reaction Mechanisms in Heterogeneous Catalysis Revealed by in situ NMR Spectroscopy
Authors: Blasco Teresa
Published: March 2011

Review: 58 refs.
ChemInform Abstract: Fluorescence Micro(spectro)scopy as a Tool to Study Catalytic Materials in Action
Authors: De Cremer Gert , Sels Bert F. , De Vos Dirk E. , Hofkens Johan , Roeffaers Maarten B. J.
Published: March 2011

Review: 82 refs.
Morphologic Pattern of Late Gadolinium Enhancement in Takotsubo Cardiomyopathy Detected by Early Cardiovascular Magnetic Resonance
Authors: Avegliano Gustavo , Huguet Marina , Costabel Juan P. , Ronderos Ricardo , Bijnens Bart , Kuschnir Paola , Thierer Jorge , Tobón‐Gomez Carolina , Martinez Guillermo Oller , Frangi Alejandro
Published: March 2011

Background:

Takotsubo cardiomyopathy (TTC) presents clinically as an acute coronary syndrome. It is characterized by transient left ventricular wall dyskinesis‐akinesis, without significant epicardial coronary lesions. Late gadolinium enhancement (LGE) sequences on cardiac magnetic resonance (CMR) allow to clarify the pathophysiology in patients with chest pain, elevated troponin, and normal epicardial coronary arteries; in patients with TTC, previous studies have shown absence of LGE.

Hypothesis:

Early CMR in Takotsubo patients could show a morphological pattern of LGE improving clinical diagnosis.

Methods:

Between January 2005 and January 2007, 8 consecutive patients with TTC criteria underwent CMR within the first 3 days of admission. Cine, T2‐weighted, and LGE images were acquired. Patient follow‐up included clinical exam and imaging techniques: echocardiogram on days 3, 7, 30, and 60, and CMR at 3 months.

Results:

Six patients had experienced a previous stressful situation. No significant lesions were found on coronary angiography, and wall motion improvement was noted at 15 (7–30) days. Median EFs at admission and recovery were 46.5% and 65%, respectively. Dyskinesis was midapical in 6 cases, apical in 1 case, and mid‐ventricular in 1 case. Late gadolinium enhancement showed mild hyperenhancement in areas of abnormal wall motion, whereas normal segments had no contrast enhancement. On follow‐up CMR, wall motion was normal without late enhancement.

Conclusions:

Early CMR in TTC demonstrates a special morphological pattern of late gadolinium uptake that might correspond to localized inflammation and edema in the affected area, suggesting diffuse microcirculation damage rather than epicardial vessel involvement. © 2011 Wiley Periodicals, Inc.

The authors have no funding, financial relationships, or conflicts of interest to disclose.
Tako‐Tsubo Cardiomyopathy and Cardiac Magnetic Resonance Imaging
Authors: Schmalfuss Carsten
Published: March 2011

The author has no funding, financial relationships, or conflicts of interest to disclose.
Surface waves on steady perfect‐fluid flows with vorticity
Authors: Burton G. R. , Toland J. F.
Published: March 2011

This is a theory of two‐dimensional steady periodic surface waves on flows under gravity in which the given data are three quantities that are independent of time in the corresponding evolution problem: the volume of fluid per period, the circulation per period on the free stream line, and the rearrangement class (equivalently, the distribution function) of the vorticity field. A minimizer of the total energy per period among flows satisfying these three constraints is shown to be a weak solution of the surface wave problem for which the vorticity is a decreasing function of the stream function. This decreasing function can be thought of as an infinite‐dimensional Lagrange multiplier corresponding to the vorticity rearrangement class being specified in the minimization problem. (Note that functional dependence of vorticity on the stream function was not specified a priori but is part of the solution to the problem and ensures the flow is steady.) To illustrate the idea with a minimum of technical difficulties, the existence of nontrivial waves on the surface of a fluid flowing with a prescribed distribution of vorticity and confined beneath an elastic sheet is proved. The theory applies equally to irrotational flows and to flows with locally square‐integrable vorticity. © 2011 Wiley Periodicals, Inc.
An optimal family of exponentially accurate one‐bit Sigma‐Delta quantization schemes
Authors: Deift Percy , Krahmer Felix , Güntürk C. Sınan
Published: March 2011

Sigma‐delta modulation is a popular method for analog‐to‐digital conversion of bandlimited signals that employs coarse quantization coupled with oversampling. The standard mathematical model for the error analysis of the method measures the performance of a given scheme by the rate at which the associated reconstruction error decays as a function of the oversampling ratio λ. It was recently shown that exponential accuracy of the form O(2−rλ) can be achieved by appropriate one‐bit sigma‐delta modulation schemes. By general information‐entropy arguments, r must be less than 1. The current best‐known value for r is approximately 0:088. The schemes that were designed to achieve this accuracy employ the “greedy” quantization rule coupled with feedback filters that fall into a class we call “minimally supported.” In this paper, we study the discrete minimization problem that corresponds to optimizing the error decay rate for this class of feedback filters. We solve a relaxed version of this problem exactly and provide explicit asymptotics of the solutions. From these relaxed solutions, we find asymptotically optimal solutions of the original problem, which improve the best‐known exponential error decay rate to r ≈ 0.102. Our method draws from the theory of orthogonal polynomials; in particular, it relates the optimal filters to the zero sets of Chebyshev polynomials of the second kind. © 2011 Wiley Periodicals, Inc.
Saccharification of Natural Lignocellulose Biomass and Polysaccharides by Highly Negatively Charged Heteropolyacids in Concentrated Aqueous Solution
Authors: Ogasawara Yoshiyuki , Itagaki Shintaro , Yamaguchi Kazuya , Mizuno Noritaka
Published: March 2011

Highly negatively charged heteropolyacids (HPAs), in particular H5BW12O40, efficiently promoted saccharification of crystalline cellulose into water‐soluble saccharides in concentrated aqueous solutions (e.g., 82 % total yield and 77 % glucose yield, based on cellulose with a 0.7 M H5BW12O40 solution); the performance was much better than those of previously reported systems with commonly utilized mineral acids (e.g., H2SO4 and HCl) and HPAs (e.g., H3PW12O40 and H4SiW12O40). Besides crystalline cellulose, the present system was applicable to the selective transformation of cellobiose, starch, and xylan to the corresponding monosaccharides such as glucose and xylose. In addition, one‐pot synthesis of levulinic acid and sorbitol directly from cellulose was realized by using concentrated HPA solutions. The present system, concentrated aqueous solutions of highly negatively charged HPAs, was further applicable to saccharification of natural (non‐purified) lignocellulose biomass, such as “rice plant straw”, “oil palm empty fruit bunch (palm EFB) fiber”, and “Japanese cedar sawdust”, giving a mixture of the corresponding water‐soluble saccharides, such as glucose (main product), galactose, mannose, xylose, arabinose, and cellobiose, in high yields (≥77 % total yields of saccharides based on holocellulose). Separation of the saccharides and H5BW12O40 was easy, and the retrieved H5BW12O40 could repeatedly be used without appreciable loss of the high performance.
Enabling live video streaming services realization in telecommunication networks using P2P technology
Authors: Efthymiopoulos Nikolaos , Tompros Spyridon L. , Christakidis Athanasios , Koutsopoulos Konstantinos , Denazis Spyros
Published: March 2011

Peer‐to‐peer (P2P) systems enjoy wide adoption from internet users. Success of P2P architecture is due to its ability to scale and organize dynamically the traffic according to the user resources and requests. However, P2P adoption is constrained in non‐real time applications, like content distribution and file sharing. The major reason behind this fact is the inability of P2P to deliver content within user‐desired bit rates by making optimal use of network resources. In this paper we focus on the solution and implementation of technical problems toward a complete system implementation that delivers live multimedia streaming through P2P architecture by the use of IMS. The content indexing and discovery, the scalable management and the distributed optimization of the graph that connects participating peers, the distributed scheduling mechanisms for data exchange, a scalable monitoring architecture and a bandwidth control mechanism constitute the major components toward a complete scalable multimedia streaming system offering streaming stability and high performance. Copyright © 2011 John Wiley & Sons, Ltd.
Evaluating and Regulating the Impacts of Lobbying in theEU? The Case Study of Green Industries
Authors: Svendsen Gert Tinggaard
Published: March 2011

How should we evaluate and regulate the impacts of lobbying in the European Union (EU)? The current lack of transparency around lobbying activities and the absence of formal regulation mean that a hidden lobbying problem may prevail. The tentative case study of green industries in the EU is illustrative. The wind turbine industry, for example, benefits from ambitious environmental target levels for greenhouse gas reductions that will increase the future market for renewable energy. In contrast, for example, no environmental target levels exist that increase the future market shares of organic farming. Rational choice theory suggests that lobbying and group size advantages can explain the observed difference in achieving environmental target levels. The EU may learn from the US legislation as a starting point for a best‐practice solution and future evaluation of impacts of lobbying in the EU. Copyright © 2011 John Wiley & Sons, Ltd and ERP Environment
Modification of Nanocrystalline TiO2 with Phosphonate‐ and Bis(phosphonate)‐Bearing Macrocyclic Complexes: Sorption and Stability Studies
Authors: Řehoř Ivan , Kubíček Vojtěch , Kotek Jan , Hermann Petr , Száková Jiřina , Lukeš Ivan
Published: March 2011

The first systematic study of chemical adsorption/desorption of phosphonic acid and geminal bis(phosphonic acid) on/from the surface of anatase nanoparticles is reported. Stable TiO2 colloidal nanodispersions were used in the study. The colloidal stability is preserved upon nanoparticle modification. A macrocyclic lanthanide(III) complex, attached through a phosphonic/bis(phosphonic) group to the TiO2 surface allowed precise quantification of sorption parameters by means of inductively coupled plasma atomic emission spectroscopy (ICP‐AES). Results show different behavior of phosphonate and bis(phosphonate) groups. For phosphonate, a monomolecular layer formation was observed, and the desorption rate depends on the sorption conditions. It is probably caused by different phosphonate binding modes on the surface. Excess amounts of phosphate in the washing media accelerates the desorption rate of the phosphonate. The bis(phosphonate) is adsorbed on the surface in large quantities forming multilayers that resist desorption even in the presence of phosphate ions and, thus, the bis(phosphonate) moiety is a suitable group for anchoring other molecules on the TiO2 particle surface.
Metal–Metal Bonding in Bis(alkylthio)hexacarbonyldicobalt Complexes: Open Structures vs. Butterfly and Tetrahedrane Structures
Authors: Sárosi Menyhárt B. , Silaghi‐Dumitrescu Ioan , King R. Bruce
Published: March 2011

Density functional calculations on the Co2(CO)6(SR)2 compounds (R = CH3, CF3) predict both open and butterfly structure types of similar energies. The open Co2(CO)6(μ‐SR)2 structures have non‐planar central Co2S2 units with two bridging RS groups and ca. 3.4 Å Co···Co distances indicating a lack of direct metal–metal bonding. The butterfly Co2(CO)5(μ‐SR)(μ‐CO)(SR) structures have direct Co–Co bonds of lengths ca. 2.5 Å forming the “body” of the butterfly, one terminal RS group, one bridging RS group, and one bridging CO group. The lowest energy Co2(CO)6(SCH3)2 structure is an open isomer. However, this open isomer lies only 0.4 kcal/mol below the corresponding butterfly isomer. For the corresponding fluorinated derivative Co2(CO)6(SCF3)2 a butterfly structure with a direct Co–Co bond and a bridging CO group lies at a slightly lower energy than the lowest energy open structures. The relative energy difference between open and butterfly Co2(CO)6(SCF3)2 structures is more than five times higher than for the Co2(CO)6(SCH3)2 structures. The electronegativity of the RS group in the Co2(CO)6(SR)2 structures has little effect on the geometric parameters but exerts a significant influence on the atomic charge distribution. The butterfly structures with a direct metal–metal bond are predicted to be nearly isoenergetic to open structures without a Co–Co bond. Unsuccessful attempts to optimize a previously proposed Co2(CO)6(μ‐η2:η2‐S2R2) structure with a central Co2S2 tetrahedrane unit with one Co–Co bond, one S–S bond, and four Co–S bonds are consistent with the previous reformulation of the originally claimed Co2S2 tetrahedranes Co2(CO)6[μ‐η2:η2‐S2(C6X5)2] (X = F, Cl) as the trinuclear derivatives Co3(μ3‐S)(C6F5)(CO)8.
Role of Siloxides in Transition Metal Chemistry and Homogeneous Catalysis
Authors: Krempner Clemens
Published: March 2011

The role of siloxide ligands in the chemistry and catalysis of transition metals is reviewed. The first part deals with recent aspects of low‐valent transition metal siloxide chemistry, while the second part describes some developments in the chemistry of transition metal siloxides in high oxidation states, in particular with regard to the stability of the M–OSi bond. The third part highlights applications of well‐defined late and early transition metal siloxides as “single site” catalysts in homogeneous catalysis. Special emphasis is placed on the steric and electronic influence of the siloxide ligand on the activity, selectivity, and stability of the catalytically active metal species.
DNA Photocleavage and Cytotoxic Properties of Ferrocene Conjugates (Eur. J. Inorg. Chem. 9/2011)
Authors: Maity Basudev , Chakravarthi Balabhadrapatruni V. S. K. , Roy Mithun , Karande Anjali A. , Chakravarty Akhil R.
Published: March 2011

The cover picture shows “bioorganometallics in PDT” in which a ferrocene‐conjugated imidazophenanthroline derivative exhibits significant photocytotoxic effects in human cervical cancer HeLa cells in visible light, while being less cytotoxic in the unexposed state. The compound is also an efficient DNA snapper in visible light. Details are discussed in the article by A. R. Chakravarty et al. on p. 1379 ff.
Homocoupling of Terminal Alkynes Catalysed by Ultrafine Copper Nanoparticles on Titania
Authors: Alonso Francisco , Melkonian Taki , Moglie Yanina , Yus Miguel
Published: March 2011

Copper nanoparticles on titania effectively catalyse the oxidative homocoupling of terminal alkynes in the presence of piperidine as a base in tetrahydrofuran (THF) or under solvent‐free conditions. A wide range of diynes have been synthesised in high yields using low catalyst loading (1 mol‐% Cu). The copper catalyst (mainly as Cu2O) has been characterised by different means, is easy to prepare, can be reutilised several times, works either in air or under inert atmosphere and was shown to be superior to other commercially available copper sources.
Linking ecology with economy: Insights into polyhydroxyalkanoate‐producing microorganisms
Authors: Koller Martin , Gasser Ilona , Schmid Florian , Berg Gabriele
Published: March 2011

Polyhydroxyalkanoates (PHA) constitute a group of microbial biopolyesters with important ecosystem functions and a high biotechnological potential. During the past decade, the rapid development of new molecular and microscopic techniques resulted in novel insights into the ecology of PHA‐producing bacteria in aquatic and terrestrial microenvironments. Ecosystems showing fluctuating availability of carbon or transient limitation of essential nutrients, e.g. the rhizosphere of plants or estuarine sediments, contain a broad number of various PHA producers. PHA‐producing microorganisms show a widespread phylogenetic diversity and are often characterized by a symbiotic or syntrophic life style. PHA are already produced commercially in large‐scale fermentation. However, they have to compete economically with petrol‐based polymers. Hence, the development of low‐cost production strategies on the basis of diverse renewable materials is a crucial challenge. Ecological knowledge is required for these developments, which links both parts of the review together. The article highlights how a better understanding of the ecology of PHA‐producing microorganisms can lead to a broader application of microbial biopolymers on the basis of sustainable production processes. These processes have to be evaluated by means of life cycle assessment and Cleaner Production studies prior to their industrial implementation.
Disordered Eating Prevention Programme in Schools: A 30‐Month Follow‐up
Authors: González Marcela , Penelo Eva , Gutiérrez Teresa , Raich Rosa M.
Published: March 2011

Objective

The present study aims to evaluate the long‐term effects of a school‐based prevention programme administered to adolescents; the purpose of the said programme was to reduce disordered eating attitudes and sociocultural influences on the internalisation of the aesthetical body ideal.

Methods

A total of 254 girls and 189 boys were assigned to a control (n = 201) or to two experimental conditions: media literacy programme (n = 143) and media literacy plus nutrition awareness programme (n = 99). Pretest, post‐test (1 month later) and 7‐month and 30‐month follow‐up measurements were taken using the Eating Attitudes Test (EAT‐40) and the questionnaire on influences of aesthetic body ideal‐26/cuestionario de influencias del modelo estético corporal (CIMEC‐26). Linear mixed‐model analyses were conducted with a 2 × 3 × 3 ANOVA (sex × group × phase), adjusted by the baseline level.

Results

The participants from both prevention programmes scored lower than the participants in the control group at follow‐up assessments on EAT‐40 and CIMEC‐26 scores.

Discussion

Both media literacy‐based programmes can be effective interventions reducing long‐term self‐reported disordered eating attitudes and internalisation of the aesthetic body ideal in a universal mixed‐sex school‐going adolescent population. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
A Psychometric Exploration of an Italian Translation of the SCOFF Questionnaire
Authors: Pannocchia Linda , Di Fiorino Mario , Giannini Marco , Vanderlinden Johan
Published: March 2011

The SCOFF is a quick and simple screening tool for eating disorders (EDs), intended for use by those who are not specialists in the field. The purpose of the present study is to explore the psychometric properties of an Italian version of the instrument. An Italian translation of the SCOFF was administered, together with a part of the Italian version of the Eating Disorders Inventory‐3, to the following: (i) a sample of psychiatric patients diagnosed with ED according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; (ii) a sample of female psychiatric controls with no ED symptoms; and (iii) a sample of female normal controls without EDs from the general population. Results suggest that the Italian version of the SCOFF provides a reliable and valid tool for screening EDs. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
Daily FX Volatility Forecasts: Can the GARCH(1,1) Model be Beaten using High‐Frequency Data?
Authors: Mcmillan David G. , Speight Alan E. H.
Published: March 2011

Volatility forecasting remains an active area of research with no current consensus as to the model that provides the most accurate forecasts, though Hansen and Lunde (2005) have argued that in the context of daily exchange rate returns nothing can beat a GARCH(1,1) model. This paper extends that line of research by utilizing intra‐day data and obtaining daily volatility forecasts from a range of models based upon the higher‐frequency data. The volatility forecasts are appraised using four different measures of ‘true’ volatility and further evaluated using regression tests of predictive power, forecast encompassing and forecast combination. Our results show that the daily GARCH(1,1) model is largely inferior to all other models, whereas the intra‐day unadjusted‐data GARCH(1,1) model generally provides superior forecasts compared to all other models. Hence, while it appears that a daily GARCH(1,1) model can be beaten in obtaining accurate daily volatility forecasts, an intra‐day GARCH(1,1) model cannot be. Copyright © 2011 John Wiley & Sons, Ltd.
Forecasting Aggregated Moving Average Processes with an Application to the Euro Area Real Interest Rate
Authors: Sbrana Giacomo
Published: March 2011

This paper focuses on the contemporaneous aggregation of moving average processes. It is shown that aggregating across second (or first)‐order (integrated) moving average processes leads to a macro process whose parameters are exact functions of the parameters of its generation process. Similar results are obtained at single equation level when a vector moving average framework is considered. In addition, the out‐of‐sample forecasting properties of aggregate and disaggregate procedures to forecast the aggregate variable are provided. Moreover, it is shown that the condition of equality of aggregate and disaggregate predictors is not necessary for the equality of their mean squared errors. Finally, an application to the euro area real interest rate is presented and discussed. Copyright © 2011 John Wiley & Sons, Ltd.
Do Long‐Run Theory Restrictions Help in Forecasting?
Authors: Mahdi Barakchian S.
Published: March 2011

Do long‐run equilibrium relations suggested by economic theory help to improve the forecasting performance of a cointegrated vector error correction model (VECM)? In this paper we try to answer this question in the context of a two‐country model developed for the Canadian and US economies. We compare the forecasting performance of the exactly identified cointegrated VECMs to the performance of the over‐identified VECMs with the long‐run theory restrictions imposed. We allow for model uncertainty and conduct this comparison for every possible combination of the cointegration ranks of the Canadian and US models. We show that the over‐identified structural cointegrated models generally outperform the exactly identified models in forecasting Canadian macroeconomic variables. We also show that the pooled forecasts generated from the over‐identified models beat most of the individual exactly identified and over‐identified models as well as the VARs in levels and in differences. Copyright © 2011 John Wiley & Sons, Ltd.
Variability of fMRI‐response patterns at different spatial observation scales
Authors: Ball Tonio , Breckel Thomas P.K. , Mutschler Isabella , Aertsen Ad , Schulze‐Bonhage Andreas , Hennig Jürgen , Speck Oliver
Published: March 2011

Functional organization units of the cerebral cortex exist over a wide range of spatial scales, from local circuits to entire cortical areas. In the last decades, scale‐space representations of neuroimaging data suited to probe the multi‐scale nature of cortical functional organization have been introduced and methodologically elaborated. For this purpose, responses are statistically detected over a range of spatial scales using a family of Gaussian filters, with small filters being related to fine and large filters—to coarse spatial scales. The goal of the present study was to investigate the degree of variability of fMRI‐response patterns over a broad range of observation scales. To this aim, the same fMRI data set obtained from 18 subjects during a visuomotor task was analyzed with a range of filters from 4‐ to 16‐mm full width at half‐maximum (FWHM). We found substantial observation‐scale‐related variability. For example, using filter widths of 6‐ to 8‐mm FWHM, in the group‐level results, significant responses in the right secondary visual but not in the primary visual cortex were detected. However, when larger filters were used, the responses in the right primary visual cortex reached significance. Often, responses in probabilistically defined areas were significant when both small and large filters, but not intermediate filter widths were applied. This suggests that brain responses can be organized in local clusters of multiple distinct activation foci. Our findings illustrate the potential of multi‐scale fMRI analysis to reveal novel features in the spatial organization of human brain responses. Hum Brain Mapp, 2011. © 2011 Wiley‐Liss, Inc.
Further Alkaloids from the Fruits of Daphniphyllum longeracemosum
Authors: Yang Ting‐Quan , Di Ying‐Tong , He Hong‐Ping , Zhang Qiang , Zhang Yu , Hao Xiao‐Jiang
Published: March 2011

Three new Daphniphyllum alkaloids, daphlongeranines C–E (1–3), along with 13 known ones, were isolated from the fruits of Daphniphyllum longeracemosum. Their structures were elucidated on the basis of extensive spectroscopic analyses, especially 2D‐NMR experiments.
Two New Cytotoxic Naphthoquinones from Didymocarpus hedyotideus
Authors: Xiao Xi‐Bin , Lin Yue‐Xing , Xu Geng‐Bo , Gong Xu‐Bo , Gu Ying , Tong Jie‐Feng , Yang Jing
Published: March 2011

A new naphthoquinone, 6‐hydroxy‐α‐dunnione (1) and a new binaphthoquinone, methyl 1,1′,4,4′‐tetrahydro‐3‐hydroxy‐1,1′,4,4′‐tetraoxo[2,2′‐binaphthalene]‐3′‐carboxylate (2), along with ten known compounds, including naphthoquinones, anthraquinones, and phenylethanoid glucosides, were isolated from the roots of Didymocarpus hedyotideus Chun. Their structures were identified by spectroscopic analyses, particularly 1D‐ and 2D‐NMR spectroscopy. The cytotoxic activities of the two new naphthoquinones were also evaluated.
Mechanism of (Salen)manganese(III)‐Catalyzed Oxidation of Aryl Phenyl Sulfides with Sodium Hypochlorite
Authors: Chellamani Arunachalam , Harikengaram Sivalingam
Published: March 2011

The oxidation of 4‐substituted phenyl phenyl sulfides was carried out with several oxo(salen)manganese(V) complexes in MeCN/H2O 9 : 1. The kinetic data show that the reaction is first‐order each in the oxidant and sulfide. Electron‐attracting substituents in the sulfides and electron‐releasing substituents in salen of the oxo(salen)manganese(V) complexes reduce the rate of oxidation. A Hammett analysis of the rate constants for the oxidation of 4‐substituted phenyl phenyl sulfides gives a negative ρ value (ρ=−2.16) indicating an electron‐deficient transition state. The log k2 values observed in the oxidation of each 4‐substituted phenyl phenyl sulfide by substituted oxo(salen)manganese(V) complexes also correlate with Hammett σ constants, giving a positive ρ value. The substituent‐, acid‐, and solvent‐effect studies indicate direct O‐atom transfer from the oxidant to the substrate in the rate‐determining step.
Efficient and Chemoselective Methods for the Synthesis of Some Isobenzofuran and Spiro[isobenzofuran‐1,2′‐pyrrole] Derivatives
Authors: Mohammadizadeh Mohammad R. , Firoozi Neda , Aradeh R.
Published: March 2011

An efficient and practical one‐pot procedure for the direct chemoselective synthesis of isobenzofuran and spiro[isobenzofuran‐1,2′‐pyrrole] derivatives is developed via oxidative cleavage of 3a,8b‐dihydroxyindeno[1,2‐b]pyrrol‐4‐ones with Pb(OAc)4 at room temperature.
Terpenes from Schisandra sphenanthera
Authors: Jiang Yan , Yang Guang‐Zhong , Chen Yu , Liao Mao‐Chuan , Liu Xiang‐Ming , Chen Su , Liu Lu , Lei Xin‐Xiang
Published: March 2011

One novel, highly oxygenated nortriterpenoid, schintrilactone C (1), and four known compounds, 2–5, were isolated from the rattan of Schisandra sphenanthera. Their structures were determined by analysis of 1D‐ and 2D‐NMR spectroscopic data. Schintrilactone C is the third example of wuweiziartane‐type nortriterpenoids, bearing a modified five‐membered D ring, a δ‐lactone E ring, and a spirocyclic moiety in the side chain at C(13).
N‐Bromosuccinimide (NBS): A Novel and Efficient Catalyst for the Synthesis of 14‐Aryl‐14H‐dibenzo[a,j]xanthenes under Solvent‐Free Conditions
Authors: Habibzadeh Setareh , Ghasemnejad Hassan , Faraji Mohammad
Published: March 2011

A novel procedure for the synthesis of 14‐aryl‐14H‐dibenzo[a,j]xanthenes through one‐pot condensation of naphthalen‐2‐ol with arenecarbaldehydes in the presence of N‐bromosuccinimide (NBS) as catalyst under solvent‐free conditions is described.
On the Reactivity of (−)‐(R)‐Carvone and (−)‐4aα,7α,7aβ‐Nepetalactone: Synthesis of New Heterocycles
Authors: El Mebtoul Aziz , Rouani Mohamed , Chammache Malika , Bouidida Houcine , Ilidrissi Abdelkader
Published: March 2011

The 1,3‐dipolar cycloaddition of 4‐chlorobenzonitrile oxide to the unsaturated system of (−)‐(R)‐carvone occurred exclusively at C(8) to give a new isoxazoline derivative. This derivative reacts with NH2OH to yield a new heterocycle, observed for the first time. On the other hand, the addition of 4‐chlorobenzonitrile oxide to the unsaturated lactone (−)‐4aα,7α,7aβ‐nepetalactone gave, in a good yield, also a new heterocycle, again obtained for the first time. The terpenoid (−)‐(R)‐carvone and iridoid (−)‐4aα,7α,7aβ‐nepetalactone were isolated from Moroccan species Mentha viridis (L.) and Nepeta tuberosa (L.), respectively. The new heterocycles obtained were identified by combination of chromatographic and spectroscopic methods.
Two New Alkaloids from the Aerial Part of Peganum nigellastrum
Authors: Yang Fei , Chen Rong , Feng Lin , Li Hai‐Dao , Zhang Hua
Published: March 2011

Two new alkaloids, pegamine β‐D‐glucopyranoside (1) and 2‐deoxypeganylacetic acid (2), together with the novel 3,4‐dihydro‐4‐hydroxynaphthalene‐2‐carboxylic acid (3), were isolated from the aerial part of Peganum nigellastrum. The structures of these compounds were elucidated on the basis of spectroscopic analyses, including 1D‐ and 2D‐NMR, and ESI‐MS/MS.