bluuebunny/crossref_metadata_2025 huggingface dataset:
Midkine as an Early Biomarker of Contrast-induced Acute Kidney Injury in Chronic Kidney Disease Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Single-center Prospective Study
Authors: Ahmed Mohamed , Ibrahim Gamal Hamed , Adel Mahmoud , Ismail Amira , Almaghraby Abdallah , Abdelnabi Mahmoud
Published: October 2021

Background: Contrast-induced acute kidney injury (CI-AKI), is an important complication of percutaneous coronary intervention (PCI). We aimed to study the role of serum midkine (MK) as an early biomarker of CI-AKI.
Methods: We conducted a prospective observational cohort study. It includes 100 chronic kidney disease (CKD) patients with an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73m2. All patients were undergoing PCI for ACS. We measured serum midkine before, 2 and 24 hours after PCI. 
Results: The mean age of the patients was 70.32±3.62 years, 74% males. Twenty-seven patients developed CI-AKI. The CI-AKI group has a history of diabetes mellitus (DM) and/or dyslipidemia, history of diuretics, metformin and/or angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers (ACEI/ARBs) use. The CI-AKI patients have low left ventricular ejection fraction (LVEF) (EF < 45%) and low Creatinine Clearance (CrCl) before PCI. The CI-AKI received more contrast volume, had a longer duration of PCI  and had high Mehran risk score after PCI. Comparison between the two studied groups regarding serum MK showed that there was a statistically significant difference regarding serum MK 2 hours after PCI. Receiver operating characteristic (ROC) curve analysis for serum MK showed that serum MK measured 2 hours after PCI was statistically significant to predict CI-AKI.
Conclusion: An early Serum MK after PCI can be used as an early predictor of CI-AKI in ACS patients.
The Behavior of Using Masks during the Coronavirus Disease 19 Pandemic in Malang Regency, Indonesia: Application of Theory of Planned Behavior and Social Support
Authors: Fikriana Riza , Afik Al , Marinda Mila Maula
Published: October 2021

BACKGROUND: The use of masks during the coronavirus disease 2019 (COVID-19) pandemic is one of the efforts to prevent its transmission. However, it was found that the behavior of the use of masks in the community is still low.

AIM: This study aims to analyze people’s behavior in the use of masks with the theory of planned behavior and social support approach.

METHODS: Research using a cross-sectional design. The study was conducted on 90 people in Malang, Indonesia, taken with simple random sampling techniques. Variables measured are behavioral beliefs, evaluation of behavioral outcomes, normative beliefs, motivation to comply, control beliefs, perceived power, attitude, subjective norm, perceived control, intention, family support, peer support, and mask usage behavior. Research instrument is questionnaire. The data were analyzed using a linear regression test.

RESULTS: Results showed that the behavior of mask use according to the theory of planned behavior was significantly influenced by perceived power (p < 0.001), normative beliefs (p = 0.019), and intention to perform the behavior (p = 0.041). While in the social support component, peer support obtained a significant effect (p = 0.002).

CONCLUSION: As an effort to improve the behavior of the use of masks in the community during the COVID-19 pandemic, it is necessary to strengthen perceived power, normative beliefs, and intentions accompanied by good peer support so that the community complies with the use of masks for the prevention of transmission.
Health Belief Associated with Adherence to Health Protocol in Preventing Coronavirus Diseases on Patients’ Family
Authors: Fikriana Riza , Fahrany Frastiqa , Rusli Syahril Ali
Published: October 2021

BACKGROUND: Adherence with health protocols during the Coronavirus disease (COVID-19) pandemic is very important to prevent transmission. However, it is obtained that adherence with health protocols is still not optimal. The hospital environment is an area that is at high risk of transmission.

AIM: The purpose of this study is to analyze the relationship between health belief and adherence with the health protocol in the patient’s family.

METHODS: Quantitative research is correlated with a cross-sectional approach. The sample is the family of patients at the hospital, which was taken with simple random sampling technique as many as 100 people. Research variables include perceived susceptibility, perceived severity, perceived benefits, perceived barrier, self-efficacy, and adherence with health protocols. Data collection was using questionnaire instruments. Data analysis was using Fisher test with a significance level of 95%.

RESULTS AND DISCUSSION: Fisher’s test results obtained data that there is a relationship between health belief in the dimensions of perceived susceptibility (p = 0.007), perceived severity (p = 0.027), perceived benefits (p = 0.003), perceived barriers (p = 0.021), and self-efficacy (p = 0.002) with adherence with health protocols in an effort to prevent the transmission of COVID-19. The patient’s family will be willing to implement health protocols if they have a high health belief in efforts to prevent the transmission of COVID-19. This health belief includes the belief that COVID-19 disease is easily contagious and serious; adherence will provide benefits for health.

CONCLUSION: Health beliefs are significantly related to adherence with health protocols in the prevention of COVID-19 transmission in the patient’s family.
Saliva Iron Levels to Assess Iron Status in Children
Authors: Flora Rostika , Zulkarnain Mohammad , Fajar Nur Alam , Yuliana Indah , Tanjung Risnawati , Nolia Helfi , Sulaiman Sulaiman , Aguscik Aguscik
Published: October 2021

BACKGROUND: Iron plays an essential role in the process of neurotransmitter synthesis and neuron myelination. Iron deficiency impacts low cognitive performance, even involved in long-term effects even though iron deficiency has been overcome. Given the impact caused by iron deficiency, it is necessary to monitor the status of iron in the body. Diagnostic tests carried out so far use blood specimens taken with invasive method. This creates fear for the child because of the pain it causes.

AIM: This study aims to obtain a non-invasive alternative diagnostic test in detecting iron deficiency in children using saliva as an examination specimen.

METHODS: The design of this study was case control, with a sample of elementary school children aged 9–12 years and for women who had not experienced menstruation. The sample consisted of 40 people who were taken randomly and grouped into iron deficiency and normal. Determine the group of iron deficiency and normal was based on the results of an examination of serum iron levels. Next, saliva samples were taken to determine saliva iron levels. The characteristics of the sample data were obtained through a questionnaire, while the measurement of serum iron levels was carried out by the spectrophotometric method, and the measurement of saliva iron levels was carried out by the ELISA method. Data were analyzed using Spearman’s test.

RESULTS: Based on serum iron measurements, it was found that the mean serum iron levels in children with iron deficiency were lower than normal children (38.153 ± 8.99 q/dL vs. 79.198 ± 14.2219 q/dL), on the contrary, on examination of iron levels, it was found that in children with iron deficiency, saliva iron levels were higher than in normal children (5.745 ± 3.04 q/dL vs. 2,576 ± 1.43 q/dL). The correlation test results showed a significant negative correlation between serum iron levels and moderate iron levels (p = 0.000, r = –0.518).

CONCLUSION: Saliva iron levels can be used as an alternative non-invasive diagnostic test to assess children’s iron status.
The Effect of Ascorbic Acid on Interleukin-10 and Tumor Necrosis Factor-α Cytokines in Rattus norvegicus with Endometritis
Authors: Prabudi Muhammad Oky , Siregar M. F. G. , Nasution I. P. A. , Ilyas S.
Published: October 2021

BACKGROUND: Endometritis is a gynecological disease characterized by inflammation of the endometrial glands and stroma. Inflammatory stimuli or tissue injury induce inflammatory pain through the release of cytokines. Ascorbic acid (AA) is a water-soluble Vitamin that plays a role in inhibiting the production of proinflammatory cytokines and increases the expression of anti-inflammatory cytokines. AIM: The purpose of this study was to find out the association between administration of AA and inflammatory cytokines in experimental animals Rattus norvegicus with endometritis. METHODS: The research was conducted using virgin female R. norvegicus laboratory mice weighing 250–300 g and aged 11–12 weeks with an estrus cycle of 5–6 days. Mice with regular oestrous cycles were randomly divided into three groups: group 1 was given 200 L of water orally without Escherichia coli inoculation and represented a negative control. Groups 2 and 3 were inoculated (50 L/rat) E. coli intravaginally, 106 colony-forming unit/mL, Group 2 was not given AA and the other side Group 3 was assigned AA. The interleukin (IL)-10 and tumor necrosis factor (TNF)-α _cytokines examination was carried out by histopathological examination through a biopsy of the endometrial tissue. Hypothesis testing on the data was analyzed by the Kruskal Wallis test using Statistical Package for Social Sciences. RESULTS: Data from the current study revealed that the highest mean value of IL-10 was found in the negative control group (2.5) and the lowest value in the positive control group (1.3). Regarding TNF-α _the highest mean value (2.8) was found in the treatment group and the lowest mean value (2.1) was found in the treatment group. Using the Kruskal Wallis test, IL-10 and TNF-α _showed insignificant results (p = value 0.304 and 0.145 respectively). CONCLUSIONS: The administration of AA did not affect the decrease in TNF-α _or the upregulation of IL-10 as anti-inflammatory cytokines.
Concordance between Triglyceride Glucose Index and Admission Insulin Resistance Index in Non-diabetic Subjects of Acute Coronary Syndrome
Authors: Irham Andi , Umar Husaini , Adam Fabiola Maureen Shinta , Mappangara Idar , Bakri Syakib , Halim Risna , Zainuddin Alfian
Published: October 2021

BACKGROUND: Acute coronary syndrome (ACS) is the leading cause of death in the world and is closely related to insulin resistance (IR). The examination of the triglyceride glucose (TyG) Index and admission IR index (AIRI) can be an alternative examination to assess IR.

AIM: The aim of the study was to analyze the concordance between the TyG index and AIRI in assessing IR in nondiabetic subjects of ACS.

METHODS: This study was a cross-sectional study using secondary data from ACS patient medical records in Wahidin Sudirohusodo Hospital Makassar from September 2020 until April 2021. An examination of RBG, TyG, and fasting insulin was performed. The statistical test results were considered significant if the p < 0.05.

RESULTS: This study included 67 subjects, of which 54 were male and 13 were female, there were 24 people aged <50 years, 43 people aged 50 years old, with a mean of 55.15 ± 12.71 years, a diagnosis of ST-elevation myocardial infarction (STEMI) 25 people, non STEMI 34 people and unstable angina pectoris 8 people, p < 0.05. The receiver operating characteristic curve showed that the cut-off value of the TyG index in predicting AIRI was 3141, with a sensitivity of 88.98% and specificity of 59.09%. The OR value revealed that subjects with a TyG index of >9.06 indicated an 11-time greater risk for IR than subjects with a TyG index ≤9.06.

CONCLUSIONS: There was a significant concordance between the TyG index and the AIRI in non-diabetic acute coronary syndrome patient.
Comparative Evaluation of SARS-CoV-2 Rapid Immunochromatographic Test Assays with Chemiluminescent Immunoassay for the Diagnosis of COVID-19
Authors: Ismail Ghada , Abdel Halim Rania , Mostafa Marwa Salah , H Abdelhamid Dalia , Abdelghaffar Hossam , Omar Nashwa Naguib , Fahim Noha Alaa Eldin
Published: October 2021

Background
To date, the molecular assay is the gold-standard method for COVID-19 diagnosis. However, they are expensive and complex. There is a pressing necessity for developing other effective diagnostics for SARS‐CoV‐2 patients. Therefore, serological detection of antibodies against SARS‐CoV‐2 might provide a good alternative.
Aim
We aimed to compare and evaluate seven rapid diagnostic tests with Mindray chemiluminescent automated immunoassay as a reference method for SARS-CoV-2 antibodies detection.
Methods:
This study included the serum of a total of 49 attendees to the Reference Laboratory of Egyptian university hospitals during the period from April 2021 to May 2021. Anti-Covid-19 antibodies detection in serum samples was performed by Mindray fully automated system as our reference method and seven rapid antibody tests; Wondfo, Vazyme, Dynamiker, Panbio, Artron Maccura and Roche.
Results:
The chemiluminescent assay revealed 30 (61.2%) positive samples and 19 (38.8%) negative samples for COVID-19 IgG. For COVID-19 IgM, 11 (22.4%) samples were positive and 38 (77.6%) samples were negative. Anti-SARS-CoV-2 antibodies were not detected in any of the PCR negative individuals. The best diagnostic performance was demonstrated by Roche IgG and IgM, and Vazyme IgG and IgM antibody tests followed by Panbio. For Roche, the sensitivity and specificity for IgG and IgM were (83.3%, 89.5%) and (72.7%, 81.6%) respectively. Vazyme showed sensitivity and specificity for IgG and IgM were (77.8%, 85.7%) and (75%, 91.7%) respectively. Regards Panbio, the sensitivity and specificity for IgG and IgM were (63.6%, 87.5%) and (50%, 86.7%) respectively. Cohen’s Kappa values revealed a substantial agreement for Roche IgG, Vazyme IgG and IgM of (0.7076, 0.6250, 0.6667) respectively. The worst agreement was reported for Maccura IgG, Wondfo, and Dynamiker IgM with Cohen’s Kappa values of (0.2508, 0.1893, 0.0313) respectively.
Conclusions:
Rapid tests in our study exhibited heterogeneous diagnostic performances. Roche, Vazyme, and Panbio antibody tests showed promising results in concordance with our reference method with the best-reported results. On the other hand, the other tests were inferior and failed in providing valid and reliable results. Further studies are necessary to determine the practicality of these tests in different settings and communities.
Les parcours de vie et la psychodynamique des « cas complexes »
Authors: Bergami G. Barbosa Pablo , Journeau-Abderrahim Garance
Published: October 2021

Cette étude s’intéresse au parcours de vie des « cas complexes » de la PJJ. L’analyse mixte, quantitative, psychodynamique, et qualitative des dossiers du dispositif Étape confirme l’hypothèse d’un parcours de vie typique de ces adolescents. Carences affectives, violences intra-familiales, ruptures successives et passages à l’acte multiples créent les conditions qui rendent la rencontre adolescent-institution d’accueil difficile voire impossible, générant par là le statut d’« incasable ».
Le silence de la native
Authors: Chow Rey , Bigé Romain/Emma-Rose
Published: October 2021

Dans cet article constitué d’extraits de Writing Diaspora (1993), la théoricienne post-coloniale Rey Chow propose une critique en règle des intérêts poursuivis par la recherche académique quand elle investit les figures des subalternes et spécifiquement des « natif·ves » du monde non-occidental. Dans la lignée des travaux de Saïd sur l’orientalisme, Rey Chow dresse le portrait ironique de l’universitaire « maoïste », qui cherche le salut dans l’Orient (ou l’indigène) exotisé. À l’inverse, elle appelle à reconnaître la puissance du silence de la native, un refus de parler qui peut faire bégayer l’ordre du discours, pourvu qu’on y prête l’oreille.
Subalternité et invention politique dans les quartiers populaires
Authors: Rabaté Ulysse
Published: October 2021

Comment éviter les contradictions et les impasses de la double conscience inhérentes à la prise de parole depuis la subalternité ? En s’appuyant sur les travaux de l’historien algérien Daho Djerbal, cet article d’Ulysse Rabaté instruit une lecture décoloniale des mobilisations dans les « quartiers populaires », depuis la marche pour l’égalité et contre le racisme de 1983 jusqu’à aujourd’hui. L’auteur, militant et chercheur en sciences politiques, propose de comprendre comment ces activismes des banlieues ou des cités, comme on les a nommés, ont été marginalisés voire exclus du domaine de la politique légitime.
Optimal control for a phase field model of melting arising from inductive heating
Authors: Xiong Zonghong ,   Department of Mathematics and Statistics, Guizhou University, Guiyang, Guizhou 550025, China, Wei Wei , Zhou Ying , Wang Yue , Liao Yumei ,   School of Data Science and Information Engineering, Guizhou Minzu University, Guiyang, Guizhou, 550025, China,   School of Mathematics and Big Data, Guizhou Education University, Guiyang, Guizhou, 550018, China
Published: October 2021

Due to its unique performance of high efficiency, fast heating speed and low power consumption, induction heating is widely and commonly used in many applications. In this paper, we study an optimal control problem arising from a metal melting process by using a induction heating method. Metal melting phenomena can be modeled by phase field equations. The aim of optimization is to approximate a desired temperature evolution and melting process. The controlled system is obtained by coupling Maxwell's equations, heat equation and phase field equation. The control variable of the system is the external electric field on the local boundary. The existence and uniqueness of the solution of the controlled system are showed by using Galerkin's method and Leray-Schauder's fixed point theorem. By proving that the control-to-state operator $ P $ is weakly sequentially continuous and Fréchet differentiable, we establish an existence result of optimal control and derive the first-order necessary optimality conditions. This work improves the limitation of the previous control system which only contains heat equation and phase field equation.
The Political Awareness and Participation of University Students in post-Apartheid South Africa
Authors: Badaru Kazeem Ajasa , Adu Emmanuel Olusola
Published: October 2021

Being politically aware and participating in politics are essential determinants of a society’s democratic survival. One source of concerns for researchers of political behavior regarding post-apartheid South Africa is the low rates of youth’s political participation. There is however a dearth of empirical studies in the extant literature on the university students’ political awareness and their political participation in post-apartheid South Africa. This mixed-methods research was conducted to fill in this obvious gap. A study sample of 372 undergraduate students selected from one rural university in the Eastern Cape through the stratified random sampling techniques yielded the quantitative data, and the qualitative data were obtained from five (5) executive members of the Student Representative Council (SRC) who were purposively selected for semi-structured interviews. Both quantitative and qualitative data analyses were performed by employing simple descriptive and Pearson correlation statistics as well as a thematic content analytical approach. Results showed that nearly all the respondents demonstrated a high level of political awareness in terms of rights to vote and be voted for (99.4%), the importance of parliament, and the national constitution (99.1%) while the respondents’ levels of political participation appeared to be below average as only (49.2%) voted during the 2017 SRC election, whereas (30.4%) of them voted in the 2014 national elections. Students’ political awareness was found to be significantly correlated with their participation in political activities on-campus (r = 0.130) and off-campus (r = 0.185). In conclusion, the bivariate analysis indicated that there was a positive correlation between students’ political awareness and their participation in politics (P<0.001).
University Students’ Learning Disruption and Affordance in a Contested Learning Environment
Authors: Nur'Aini Siti
Published: October 2021

This study investigates how university students engage with their learning affordances in a contested environment due to the Coronavirus pandemic. This qualitative research employed a case study approach involving 136 participants. Data analysis was conducted using qualitative analysis as a circular process to describe, classify, and perceive the phenomenon and how the learning, affordances, and society were interconnected. The main framework of the research was the theory of affordance and how it was available for university students in their learning environment that changed due to the COVID-19 pandemic. Data were collected in the first semester of 2020 through an online survey on Google form. The findings indicate the importance of the social environment to provide affordance for the students to adjust with them. Four kinds of affordances emerged from the study; internet affordance, assignment affordance, domestic affordance, and distance learning affordance. The role of the social environment is definitive in changing how students manage their affordances.
Investigating the Effects of E-Learning as a Method of Curriculum Dissemination for Rural TVET College Students
Authors: Madimabe Makhosi P. , Omodan Bunmi I.
Published: October 2021

The study investigates the effects of e-learning as an alternative form of curriculum dissemination for rural Technical and Vocational Education and Training (TVET) college students. This study adopted connectivism theory, which enabled lecturers to reflect and adapt to how learning has changed and the accompanying implications of designing the spaces and structures to the current mode of learning. The researcher made use of two research methods to gather data; phone interviews and questionnaires. The data was analyzed using thematic analysis and the Statistical Package for Social Sciences (SPSS) Version 20.0, Office Word format. The results indicated that the unavailability of technological resources, lack of financial support from single parents’ side due to socio-economic factors, and child-headed families hinder the correct implementation of e-learning and make it difficult to reach its objectives.
Accounting Teachers’ Voices on Factors Affecting Online Teaching during the 4th Industrial Revolution in the Face of COVID-19 in Selected High Schools in the Eastern Cape, South Africa
Authors: Skhephe Melikhaya , Mantlana Christabel
Published: October 2021

The most prominent debate in South Africa is how teachers will provide instruction online. The purposes of this article was to explore Accounting teachers’ voices on factors affecting online teaching. To this end, the researchers employed a qualitative approach and a case study research design. Interviews were used as a method to collect data from 10 Accounting teachers who were purposively selected. Thematic data analysis was used.  The results revealed that, Accounting teachers are lacking required knowledge and skills needed to facilitate technology learning in their classrooms.  Results further reveal that, online teaching arrived at an awkward moment when teachers were faced with COVID-19 pandemic. The study concludes that teachers’ voices play an important role in any proposed changes in the classroom. The Eastern Cape Province where the study was conducted should quickly roll out infrastructure at all schools aiming to support online classrooms. It is recommended in this paper that teachers need to be workshopped in online teaching in order for them to perform effectively.
Cross-fertilization in Teaching and Learning between Institutions after COVID-19 Shutdown: A Collaborative Effort
Authors: Dhlamini Joyce Phikisile , Molaodi Vivian Thuso
Published: October 2021

Research reported in this article investigated the effectiveness of collaborative effort between schools to bridge the existing gaps that erupted during the outbreak of COVID-19. There are gaps in teaching and learning within the previously privileged institutions and the marginalised institutions in South Africa. Such gaps might have a negative impact on how teaching and learning are conducted. The purpose of this article was to investigate the creative and constructive ways of managing the anxiety related to socio-economic impacts in schools, amongst which were the introduction of online teaching and learning technologies, new methodologies and contents. This article is underpinned by the concepts of the establishment of advantageous strategies for collaboration, knowledge sharing and knowledge transfer. Qualitative document analysis has been adopted as a methodology to collect information for this study. The outbreak of COVID-19 has evoked inequalities amongst the communities. However, the re-opening of schools exacerbated multiple challenges. While teaching and learning is the centre of the education project in South Africa, which the country has to adapt to, most institutions were faced with a number of challenges. This study’s major finding revealed that collaboration is synergistic and can bring out the best contribution that might currently perceive partnership within the school system. This article recommends ways of bridging the gap between schools through developing partnerships between institutions through cross-fertilisation.
OUTER SHELL FLEXIBILITY IN KINETIC ARCHITECTURAL DESIGN AND UTILIZATION OF INTEGRATED SYSTEMS
Authors: İNAN Nurgül , YILDIRIM Tayfun
Published: October 2021

Today, developing technology and globalization change the cultures, lifestyles, and needs of societies. This change also impacts the expectations from architectural spaces. Spaces designed to perform a predetermined function may be insufficient to meet the changing needs over time. The aim of this study is to show the flexibility that the movable structural elements bring to the space. In this context, we propose integrating movable inner and outer shell structural elements to achieve specific functionality and meet the various functional capacity needs. In this study, a sample design was visualized to demonstrate the use of integrated kinetic building elements and was discussed its applicability with existing technologies and the advantages that it can provide. As a result, it was observed that kinetic building elements practically provide spatial flexibility and functional diversity in architectural design. In addition, the visuals show that the system is practical, applicable and efficient. Kinetic and flexible space design can be evaluated in “Generative and Parametric design” by means of to obtain variable solutions and functional sustainability according to different functional expectations from design.
A case report on pemphigus foliaceus
Authors: Muppineni Divyasree , Uppu Vishnu Sree , Shaik Dr.Firoz
Published: October 2021

Pemphigus Foliaceus (PF) is second most common autoimmune vesicular disease in the pemphigus family characterized by superficial blisters of the skin and rarely mucous membranes which rupture to produce scaly, crusted lesions. A 54 year old female patient admitted in female derma ward in tertiary care hospital, with the chief complaints of painful ruptured blisters all over the body with crusty, scaly patches associated with serous discharge and itching since 15 days. A positive Nikolsky’s sign is when the skin shears off easily when the surface is wiped sideways with a cotton swab or a finger. Based on both subjective and objective evidence, this case is assessed as Pemphigus Foliaceus. The plan incudes Corticosteroids, Immunosuppressants, Antibiotics, Vitamin A & D supplements, IV fluids, calcium and aminoacids supplements, antivirals and antifungals (if needed), proper wound management and finally plasmapheresis.
Brief review on remdesivir
Authors: Daka Venkata Niharika , Bandi Lakshmi Sravanthi , Alla Sushma , Cheedella Venkata Spandana , Galaba Sadasiva Rao
Published: October 2021

Remdesivir is an investigational broad-spectrum small-molecule antiviral drug that has confirmed interest in the direction of RNA viruses in numerous families, which encompass Coronaviridae (alongside aspect SARS-CoV, MERS-CoV, and lines of bat coronaviruses able to infecting human respiratory epithelial cells), Paramyxoviridae (alongside aspect Nipah virus, respiratory syncytial virus, and Hendra virus), and Filoviridae (alongside aspect Ebola virus). Originally superior to cope with Ebola virus infection , remdesivir is a prodrug of the determine adenosine analog, each of which can be metabolized into an energetic nucleoside triphosphate (NTP) via the host. The determine nucleoside, GS-441524, has displayed antiviral interest within the direction of SARS-CoV, Marburg virus , and pussycat infectious peritonitis virus, amongst others. A fashion of research have tested the effects of these pills on coronaviruses (CoVs) each in vitro and in vivo the use of mouse and non-human primate animal models.
Pengaruh Modal Sosial terhadap Fungsi Kognitif pada Pasien Skizofrenia di RSUD dr. Soeselo
Authors: Immanuel Glorio , Maharani Putri Prima , Finurina Mustikawati Irma
Published: October 2021

This study wanted to look at the relationship and influence of social capital on cognitive function in schizophrenic patients. Social capital is a concept that arises from the results of interaction in society with a long process and is believed to be one of the main components in driving togetherness, mobility of ideas, mutual trust and mutual benefit to achieve mutual progress. Interactions that form networks in togetherness in social capital contain norms, values and mutual understanding that facilitate cooperation in a group. Social capital is generally associated with health and is considered an important etiology in schizophrenia where in the early stages of schizophrenia there are significant cognitive symptoms making it very difficult for people with the disorder to work, study or work in social life. This research method uses the design of latitude cut study, conducted in dr. hospital. soeselo and using MMSE instruments. The results of the study found a link between social capital and cognitive symptoms in schizophrenic patients where in individuals with good social capital was shown to better adjust to cognitive function. Conclusions on individuals with good social capital can adjust better because individuals have had better coping, perception and adjustment about themselves and their environment, individuals already have the ability to maintain their communication and interaction in public life.
Peran Serta Rumah Sakit Khusus Gigi dan Mulut Selama Masa Pandemi Covid-19
Authors: Novalino Novalino , Bakti Bawono Adisasmito Wiku
Published: October 2021

The COVID-19 pandemic, which has occurred for almost 2 years, has infected more than 200 countries in the world, has made hospital conditions change the service strategy provided. Services that are usually provided during normal times, must change conditions starting from screening patients on arrival until the service ends. When referral hospitals are trying to save patients infected with COVID-19, other hospitals, especially dental and oral hospitals, also participate in removing this nation from the grip of the COVID-19 pandemic, although they do not directly treat COVID-19 patients. By using descriptive qualitative research methods, researchers can obtain deeper information from a case study at a special dental and oral hospital, which usually only provides dental services. The purpose of this study was to get an overview of the efforts made by dental and oral hospitals in providing services to the community in an effort to break the chain of transmission of COVID-19. The results obtained are an evaluation of the increase in the number of patients and dental emergency room services, the implementation of tracing and testing for all hospitalians, as well as providing vaccination services, which are things that special dental and oral hospitals can do in participating in taking part and breaking the chain of transmission of COVID-19.
Pengaruh Besarnya Ultrafiltrasi terhadap Perubahan Tekanan Darah pada Pasien PGK di Unit Hemodialisa RSUD Kabupaten Tangerang
Authors: Sulastri Sulastri , Maulidia Septimar Zahrah , Mei Winarni Lastri
Published: October 2021

The magnitude of ultrafiltration is the process of transferring dissolved substances and water due to hydrostatic differences in blood and dialysate which are carried out from the patient's body weight. The purpose of this research is of the amount of ultrafiltration on changes in blood pressure in clients with chronic kidney disease at Tangerang Regional Hospital. Methods: This study used a quasi-experimental design with a one group study, the population of all patients in the hemodialysis room, a sample of 150 people. Results: The study showed that the amount of ultrfiltration both experienced changes in normal BP was 17 respondents (50.1%), respondents with a moderate amount of ultrafiltration were experiencing a change in low BP, the most were 2 respondents (66.6%) and the number of respondents, the amount of ultrafiltration, was multiplying changes in high BP, around 42 respondents. (37.2%). Chi Square test obtained an Asymp.Sig. (2-sided) value of 0.035 <0.05, there is an influence between the amount of ultrafiltration on changes in blood pressure in CKD patients at the HD Unit of the Tangerang District Hospital 2020. Conclusion to improve hemodialysis services with restrictions and Monitoring the amount of ultrafiltration can minimize the risk of a drop in blood pressure that can endanger the patient's life.
Keefektifan E-Learning dalam Pembelajaran Mahasiswa pada Masa Pandemi
Authors: Zulfan Faizal Muhammad , Andhyka Kusuma Wahyu
Published: October 2021

Penelitian ini adalah merupakan penelitian deskriptif kualitatif yang mengkaji tentang keefektifan e-learning pada pembelajaran mahasiswa pada masa pandemi. Pembelajaran jarak jauh ini akibat terdampak pandemi covid-19 yang mengharuskan mahasiswa tidak memperoleh pembelajaran tatap muka. e-learning Merupakan sistem pembelajaran jarak jauh yang mengharuskan para mahasiswanya tetap melakukan pembelajaran meskipun tidak bisa melakukan pembelajaran tatap muka. Keefektifan juga perlu dalam sebuah pembangunan sistem pembelajaran karena dalam sistem pembelajaran keefektifan itu sangat berperan penting untuk berjalannya sistem tersebut, Jika tanpa adanya keefektifan dalam suatu pembelajaran maka akan sulit bagi pengajar maupun yang mahasiswa. Pandemi merupakan wabah penyakit yang terjadi pada seluruh dunia, dengan adanya pandemi ini bidang pendidikan mengalami kesulitan untuk melakukan pembelajaran tatap muka, maka cara pemerintah untuk menanggulangi efek menyebar dari pandemi ini diterapkannya sistem pembelajaran online atau yang bisa disebut e-learning.
Penggunaan Upaya Peningkatan dan Motivasi Belajar E- Learning Management System (LMS) Pada Saat Pandemi
Authors: Ramadhan Helmi , Andhyka Kusuma Wahyu
Published: October 2021

Saat ini pandemi covid19 masih menjadi momok menakutkan bagi manusia diseluruh dunia. Tak tanggung- tanggung segala aktivitas menjadi terganggu seperti dibidang kesehatan, ekonomi, dan tak luput juga bidang pendidikan. Akibat wabah virus covid19 hampir seluruh kegiatan ataupun sistem belajar mengajar dilakukan secara online (daring). Saat ini learning management system (LMS) semakin berkembang dengan berbagai metode yang unik dan inovatif serta membuat kegiatan belajar mengajar lebih efektif, dengan adanya banyak platform yang mudah diakses, membuat para pelajar semangat untuk menuntut ilmu. Namun tidak sedikit juga kendala yang dihadapi saat pembelajaran jarak jauh ini misalnya, keterbatasan koneksi internet dan menurunnya motivasi belajar. Di sini penulis menggunakan metode melalui wawancara kepada responden saat mengumpulkan data. Dari hasil wawancara tersebut banyak responden yang kurang puas dengan penggunaan LMS dikarenakan tampilannya masih kurang user friendly.
Analisis Proses 3D Printing terhadap Pengujian Impak Metode Charpy Pada Material PLA+
Authors: Akbar Ilham , Sirwansyah Suzen Zaldy , Idiar Idiar
Published: October 2021

Pada era industri perkembangan teknologi pada saat ini telah mengalami kemajuan yang sangat pesat, salah satunya adalah teknologi 3D printing atau juga dikenal sebagai additive manufacturing. Salah satu teknologi 3D printing yang terkenal adalah Fused Deposition Modelling (FDM). Prinsip kerja FDM adalah dengan cara ekstrusi termoplastik melalui nozzle yang panas pada melting temperature selanjutnya produk dibuat lapis perlapis. Teknologi 3D printing adalah proses pembuatan benda padat dari sebuah file digital. Penelitian ini menggunakan metode eksperimen, dilakukan pada mesin 3D printing FDM model Prusa area dengan menggunakan nozzle 0,4mm. Material yang digunakan adalah filamen PLA+ dengan diameter 1,75mm variasi parameternya nozzle temperature (205oC, 215oC, 225oC), Cooling speed (100%, 90%, 80%), infill type (grid, lines, triangles, Tri hexagon, cubic, cubic subdivision, octet, quarter qubic, concentric, zigzag, cross, cross 3D dan gyroid). Penelitian ini menggunakan 39 sampel dengan tujuan untuk mengetahui hasil uji impak tertinggi dan terendah dengan pengujian impak dari parameter yang ditentukan yaitu orientasi printing 90o. Hasil dari pengujian impak tertinggi sebesar 0,00548 Joule/mm2 dengan ekperimen nomor 32 infill geometry (cubic Subdivision), cooling speed 80% dan nozzle temperature 225ºC. Sedangkan nilai uji impak terendah sebesar 0,00084 Joule/mm2 dengan ekperimen nomor 14 dan 17 infill geometry (grid) dan (Tri hexagon), cooling speed 90%, nozzle temperature 215ºC dan ekperimen nomor 27 infill geometry grid, cooling speed 80%, nozzle temperature 225ºC. hasil pengujian impak menggunakan spesimen PLA+ didapatkan nilai uji impak sebesar 0,00548 Joule/mm2, dengan ekperimen nomor 32 infill geometry cubic subdivision, cooling speed 80%, nozzle temperature 225oC.
Pengaruh Penambahan Zat Aditif Toluena pada Bahan Bakar Premium terhadap Performa Vespa Sprint 150 3V
Authors: Siswanto Alfian , Ruslan Wegie
Published: October 2021

Pada zaman modern ini penggunaan bahan bakar bensin semakin banyak karena populasi kendaraan meingkat, yang dapat menyebabkan cadangan minyak akan habis dan harga bensin akan naik. Selain itu dapat menyebabkan polusi udara meningkat. Performa dari suatu kendaraan dapat dinilai diantaranya dari daya, torsi dan emisi gas buang yang dihasilkan, faktor yang mempengaruhi adalah penggunaan bahan bakar yang baik yaitu bensin beroktan tinggi. Penggunaan bensin beroktan tinggi sangat mempengaruhi proses pembakaran. Tujuan dari penelitian ini adalah untuk menganalisa penambahan zat aditif Toluena pada Premium dengan volume sebesar 5% dan 10% yang nantinya akan dibandingkan peningkatan performanya terhadap bahan bakar dasarnya Premium. Selanjutnya akan dibandingkan performa yang dihasilkan terhadap Pertamax dan Pertamax Turbo. Kendaraan yang digunakan adalah sepeda motor Vespa Sprint 150 3v. Pengujian dilakukan terdiri dari Pengujian daya,torsi dan spesifik konsumsi bahan bakar atau bisa disebut specific fuel consumpstion menggunakan alat dnamometer dan emisi gas buang menggunakan alat gas Analyzer, pengujian dilakukan terhadap ke lima terjadi peningkatan performa yang dihasilkan Premium campuran bahan bakar tersebut. Setelah melakukan pengujian dapat disimpulkan Toluena 5% dan 10% dibandingkan Dengan bahan bakar dasarnya. Untuk campuran Toluena 10% dalam pengujian torsi, performanya lebih tinggi dibandingkan dengan Pertamax. Dan untuk pengujian yang lainnya performa yang dihasilkan campuran Toluena masih dibawah performa Pertamax dan Pertamax Turbo. Dapat disimpulkan penambahan zat aditif Toluena pada Premium performanya mengalami peningkatan karena nilai oktan bertambah. Untuk Pertamax dan Pertamax Turbo performanya diatas campuran Toluena karena kedua bahan bakar tersebut memiliki nilai oktan yang lebih tinggi dan juga terdapat formula zat aditif buatan Ecosave yang dapat meningkatkan performa kendaraan.
Pemanfaatan Industri 4.0 dalam Pembelajaran Jarak Jauh Selama Pandemi Covid-19 Menggunakan LMS (Learning Management System)
Authors: Winanda Favourite Augie , Andhyka Kusuma Wahyu
Published: October 2021

Revolusi Industri 4.0 menuntut setiap manusia untuk mengikuti arus perkembangan zaman terlebih lagi penggunaan teknologi yang kian canggih di berbagi macam sektor, salah satu sektor yang terdampak dari arus globalisasi ini adalah sektor pendidikan.  Dimana metode pembelajaran yang sebelumnya digunakan yakni metode tatap muka dilakukan modernisasi dengan metode Blended Learning, dimana metode ini menggabungkan metode tradisional tatap muka dan metode online atau yang sering disebut E-Learning. Hal tersebut didukung dengan adanya situasi pandemi covid-19 yang mengharuskan para tenaga pengajar dan yang diajar melakukan metode Pembelajaran Jarak Jauh (PJJ). Para stakeholder terkait memiliki beberapa opsi dalam pemanfaatan teknologi Industri 4.0 diantaranya menggunakan Learning Management System (LMS) maupun Video Conference. Dengan semakin pesatnya kemajuan teknologi tersebut, tentunya mendorong para pendidik untuk terus memperbaharui media pembelajaran yang digunakan dalam mentransfer ilmu kepada peserta didik. Berdasarkan uraian tersebut, maka dilakukan pengambilan sampel literatur dengan tujuan penelitian untuk memberikan tinjauan umum terkait metode pembelajaran online yang ada di Indonesia. Hal ini penting dilakukan guna mengetahui implementasi dan dampat apa saja yang ditimbulkan pada pembelajaran online sehingga dapat memberikan informasi perbaikan kebijakan yang dilakukan.
Optimalisasi Pengembangan Pariwisata dan Potensi Ekonomi Lokal Di Kampong Waerebo Nusa Tenggara Timur
Authors: Shidqi Rabbani Syarif , Bachtiar Arief , Setya Wijaya Riko
Published: October 2021

Pengembangan suatu tempat yang dijadikan daerah pariwisata diharapkan menjadi sumber dan potensi kegiatan ekonomi yang dapat diandalkan yang mampu menggalakan kegiatan ekonomi termasuk kegiatan sektor lain sehingga lapangan pekerjaan, pendapatan masyarakat, pendapatan dan daerah, serta penerimaan devisa meningkat melalui upaya pengembangan dan pembangunan berbagai potensi kepariwisataan nasional dengan tetap memelihara kepribadian bangsa dan kelestarian fungsi serta mutu lingkungan hidup. Tujuan penelitian ini adalah untuk mengidentifikasi dan menganalisis komponen penawaran pariwisata di objek wisata Waerebo, serta mengetahui dan menganalisis pengembangan dan besarnya potensi ekonomi lokal di Waerebo. Metode penelitian yang digunakan adalah penelitian deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data dilakukan dengan observasi, wawancara, kuesioner, dokumentasi dan gabungan keempatnya. Hasil penelitian yang didapat yakni pengoptimalisasian wisata di kampung adat Waerebo dapat diterapkan melalui pengembangan-pengembangan fasilitas, baik fasilitas ketika akan menuju pada wisata kampung adat Waerebo.
Design de superfície: estamparia laser como diferencial no jeans
Authors: Silva Tharcila Maria Barros , Silva Sophia de Oliveira Costa e , Costa Andréa Fernanda de Santana
Published: October 2021

Este trabalho tem por objetivo a criação de um projeto de superfície com ênfase na produção de uma coleção de estampas para jeans, que serão reproduzidas em sua superfície utilizando uma nova tecnologia à laser. As padronagens criadas são baseadas em elementos Art Decó do filme O Grande Gatsby.

This work aims to create a surface design with emphasis on the production of a collection of prints to Jeans that will be applied on its surface using a new laser technology. The patterns are created based on Art Deco elements from the film The Great Gatsby.
Analysis of the Values of Enset (Enseteventricosum) in The Socio-Cultural Life of Thegurage of South-Central Ethiopia
Authors:   Assistant professor, Department of history and heritage management, college of social sciences and humanities, wolaita sodo university, Tesfaye Retta Eshettu
Published: October 2021

Enset (Enseteventricosum) is a traditional multi-purpose crop mainly used as a staple/co-staple food crop over 20 million people in Ethiopia. The Gurage are sedentary agricultural people of patrilineal persuasion who speak a Semetic language and inhabit in a sparsely fertile semi-mountainous regionin south-central Ethiopia. Enset, their staple food crop, commonly called the “false banana plant”, is produced in abundance by each Gurage homestead. The objective of this study was to document the socio-cultural values of enset plant among the Gurage. In this study, a qualitative methodological approach is employed in extracting information from different sources on the subject in question. The study relied mainly on primary and secondary sources.According to findings, three types of food, viz, Kocho(fermented product from scraped pseudo stem grafted corm), Bulla(dehydrated juice), and Amicho (boiled corm) can be prepared from enset. As a food crop, it has useful attributes such as foods can be stored for long time, grow in wide range of environments, produces high yield per unit area and tolerates drought. It has irreplaceable role as a feed for animals. Enset starch is found to have higher and widely used as a tablet binder and dis-integrant and also in pharmaceutical gelling, drug loading and release processes. Moreover, enset shows high genetic diversity within a population which in turn renders resilience and food security against the ever-changing environmental factors and land use dynamics.Enset is totally involved in every aspects of the daily social and ritual life of the Gurage, who, with other several tribes in southwest Ethiopia, form what has been termed “the EnsetCulture Complex Area”. From birth, when the umbilicus is tied off with a fiber drawn from enset fronds, the life of the Gurage is enmeshed with various uses of enset, not the least of which is nutritional.
Corruption and Democracy: Political Corruption in Post-Soeharto Indonesia
Authors:   Lecturer of Faculty of Social and Political Sciences, Universitas Nasional, Indonesia, Jalal Asran
Published: October 2021

Post-Soeharto Indonesia, known as the era of reform and democracy, has not been able to inhibit corrupt behaviour by state officials at the central and local government levels, in legislative and executive institutions, or in the judiciary as a judicial institution. This article discusses and analyses the corruption process carried out by state officials, especially those occupying legislative, executive, and special judicial institutions at the central government level in interacting with each other and with outside institutions. The public's hope that ongoing democracy will be able to limit political corruption in Indonesia is only an illusion, considering the democracy model that developed in Indonesia post-Soeharto led to a patronage democracy, namely the interaction of power between state institutions which is based on mutually beneficial considerations. Another consideration is that the institution that administers justice which serves as law enforcement agency is involved in corrupt practices.