bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of zero echo time MR angiography in follow-up of intracranial aneurysm remnant and in-stent lumen after embolization: a comparison study with digital subtraction angiography
Authors: Song Yan , Qi Peng , Huang Juan , Jiao Sheng , Zhang Jintao , Wang Daming , Chen Min
Published: July 2019

Background

Intracranial aneurysm with endovascular treatment needs to be followed-up with a proper imaging method.

Purpose

To evaluate the performance of magnetic resonance angiography (MRA) with zero echo time at 1.5-T in assessing the intracranial aneurysm remnant and in-stent lumen as compared with time-of-flight MRA, with digital subtraction angiography as the gold standard.

Material and Methods

A total of 46 patients (17 men; mean age = 56.6±13.7 years) with 54 aneurysms who underwent coil embolization with or without stent were enrolled in this study. The presence of aneurysm remnant and the visualization of in-stent lumen were evaluated. The agreement of remnant identification between MRA with zero echo time and time-of-flight MRA with digital subtraction angiography was evaluated using Cohen’s kappa analysis. The performance of in-stent lumen visualization between MRA with zero echo time and time-of-flight MR angiography was compared with Chi-square test.

Results

Of 54 aneurysms, 27 were found to have remnants by digital subtraction angiography. The kappa value in identification of remnant of aneurysm was 0.852 between MRA with zero echo time and digital subtraction angiography and 0.741 between time-of-flight MRA and digital subtraction angiography. In detecting remnant of aneurysm, the sensitivity, specificity, positive predictive value, and negative predictive value were 96.3%, 88.9%, 89.7%, and 96.0% for MRA with zero echo time and 91.7%, 83.3%, 81.5%, and 92.6% for time-of-flight MRA, respectively. In visualizing in-stent lumen, MRA with zero echo time had better performance than time-of-flight MRA ( P < 0.001).

Conclusion

MR angiography with zero echo time might be a better non-invasive approach in assessing remnant of aneurysms and in-stent lumen as compared with time-of-flight MRA.
Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis
Authors: Jiang Yahui , Jia Nan , Zhu Menghan , He Yuan , Che Xiaoxia , Lv Tianjiao , Feng Weiwei
Published: July 2019

Objective

We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.

Methods

A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.

Results

Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.

Conclusions

SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC.
Writing and (not) reading the Torah (and contrasting texts) in the Book of Isaiah
Authors: van Wieringen Archibald LHM
Published: July 2019

On the basis of Edgar Conrad’s pioneering exegesis of the intra-textual function of the expression סֵפֶר הַתּוֹרָה‎ and similar expressions in the Pentateuch, published in the Journal for the Study of the Old Testament 25 years ago this year, I will examine the intra-textual function of the written product, called תּוֹרָה‎, in the Book of Isaiah. Striking similarities can be found between the two intra-textual functions. The textual presence of תּוֹרָה‎ in the Book of Isaiah highlights a semantic structure throughout the book. Moreover, the prophetic תּוֹרָה‎ appears to be connected to the King character in a similar way to how the King is related to the Torah in the Pentateuch. However, the Book of Isaiah also contains two elaborations. The activity of reading (and not reading) is added to the activity of writing the intra-textual document. Furthermore, the Book of Isaiah contains a number of contrasting written products.
The volumetric city
Authors: McNeill Donald
Published: July 2019

This paper sets out a research agenda for the interrogation of urban space as being ontologically constituted by its volumetric properties: that is, the ways in which the arrangement of dimensions and capacities above, below and in relation to the surface of the city are measured. The paper reviews the nascent ‘volumetric turn’ in explaining the production of urban space, noting the growing interest among scholars in understanding how verticality, surface, and the subterranean relate to the power and political economy of cities.
Evaluation of a Training Intervention to Improve Novice Drivers’ Hazard Mitigation When Approaching Left Turn Scenarios
Authors: Muttart Jeffrey W. , Dinakar Swaroop , Fisher Donald L. , Garrison Teena M. , Samuel Siby
Published: July 2019

Crash statistics reveal that newly licensed teenage drivers experience a higher risk of crashing than more experienced drivers, particularly when turning left across the path of approaching traffic. Research has also demonstrated that novice drivers exhibit poor hazard mitigation skills. The current study assesses the effectiveness of a training program aimed at improving novice drivers’ hazard mitigation and speed selection behaviors as both the through driver and turning driver in left turn across path scenarios. In this study, novice drivers were randomly assigned to one of two training cohorts: anticipation-control-terminate (ACT) or placebo. Phase 1 of ACT is a video game where drivers must select where to look, where they would steer, and when they would slow when observing the approach to known fatal crash risk scenarios. Placebo training involved reaction time tests and street sign definitions. In phase 2 the ACT-trained participants were shown where their choices were similar to, or different than, those of drivers aged 26 through 61who had not had crashed in the previous 10 years. In phase 3, ACT-trained drivers were compared with placebo-trained drivers at left turn scenarios both as through driver and turning driver, using a driving simulator. ACT-trained drivers were more likely to exhibit anticipatory glances and slowing behaviors, and were significantly less likely to crash than were placebo-trained drivers. The results indicate that ACT was effective as a countermeasure for training novice drivers to select better speed management strategies in the simulated scenarios utilized in this research.
A Randomized Crossover Study to Evaluate Recipe Acceptability in Breastfeeding Mothers and Young Children in India Targeted for a Multiple Biofortified Food Crop Intervention
Authors: Gannon Bryan M. , Thakker Varsha , Bonam Vincent S. , Haas Jere D. , Bonam Wesley , Finkelstein Julia L. , Udipi Shobha A. , Mehta Saurabh
Published: July 2019

Background:

A multiple biofortified food crop trial targeting iron, zinc, and vitamin A deficiencies among young children and their breastfeeding mothers is planned in India.

Objective:

To determine the acceptability of recipes prepared with control and biofortified pearl millet, wheat, lentils, and sweet potato.

Methods:

Children (6-24 months) and their mothers were enrolled as pairs (n = 52). Weight and height/length were determined. Mothers and children were separately, individually randomized in a crossover design to control or biofortified recipes. Children’s 3-day intake was measured per recipe and crop variety. For mothers, a 9-point hedonic scale evaluated color, odor, taste, and overall acceptability.

Results:

Children’s mean (SD) length-/height-for-age Z-score was −1.2 (1.7), with 27% < −2 (stunted). Mean weight-for-length Z-score was −0.6 (1.2) with 9.6% < −2 (wasted). Mother’s body mass index showed 17% <18.5 and 38% >25. There was no difference in the children’s intake of biofortified versus control varieties of any recipe ( P ≥ .22); overall median daily intake was 75 g (Q1: 61, Q3: 100). Mother’s hedonic scores for color, odor, taste, or overall acceptability did not demonstrate any notable differences ( P ≥ .23 for overall acceptability); combined median overall acceptability score was 8.5 (Q1: 8.0, Q3: 9.0).

Conclusions:

Recipes were consumed readily, were rated as highly acceptable, and did not show any differences between biofortified and control varieties.
Exploring the Determinants of Variations in Land Use Policy Outcomes: What Makes Urban Containment Work?
Authors: Kim Jae Hong
Published: July 2019

This article explores ways in which land use policy outcomes vary across contexts focusing, as an example, on urban growth boundaries. Specifically, it analyzes how various contextual factors interact with the policy and generate diverging development outcomes by employing a kernel-based regularized least squares method. Results show that the policy effectiveness is largely dependent on the region’s population size, initial density levels, and organizational conditions. The presence of urban growth boundaries also appears to shape the way other determinants influence development patterns, suggesting that the policy can both directly and indirectly promote a more compact/contiguous pattern of development.
Older Consumers, Digital Marketing, and Public Policy: A Review and Research Agenda
Authors: Nunan Daniel , Di Domenico MariaLaura
Published: July 2019

Addressing the challenges created by rapidly aging populations is a topic of intense interest for marketers, policy makers, and researchers. However, relatively little research has been undertaken into the ways older consumers are adopting or rejecting new digital technologies. Given the shifting economic power and growing digital adoption rates among older consumers, understanding how they adopt technology and use digital channels is becoming increasingly important to marketers. For marketers and policy makers to fully understand the future shape of a data-driven digital society, research must take more account of its influence across different older generational cohorts. This article focuses on identifying research gaps across key digital marketing areas in relation to older-age consumers’ adoption and use of digital technology. Through a multidisciplinary review of the literature on aging, using the theoretical lens of generational cohorts, the authors identify key research challenges, opportunities, and implications for both marketers and policy makers.
The Effects of Acute Exercise on Retroactive Memory Interference
Authors: Loprinzi Paul D. , Frith Emily , Crawford Lindsay
Published: July 2019

Purpose:

Retroactive interference involves the disruption of previously encoded information from newly learned information and thus may impair the consolidation of long-term memory. The objective of this study was to evaluate whether acute exercise can attenuate retroactive memory interference.

Design:

Three experimental studies were employed. Experiment 1 employed a between-subject randomized control trial (RCT) involving moderate-intensity walking (15 minutes). Experiment 2 employed a between-subject RCT involving high-intensity jogging (15 minutes). Experiment 3 employed a within-subject RCT involving moderate-intensity walking (15 minutes).

Setting:

University setting.

Participants:

One hundred twelve young adults.

Measures:

After exercise, memory interference was evaluated from an episodic word-list memory task, involving the recall of 2 word lists.

Results:

The pooled effect size (standard difference in means: −0.35; 95% confidence interval: −0.64 to −0.06) across the 3 experiments was statistically significant ( P = .01).

Conclusion:

We provide suggestive evidence that acute, short-duration exercise may help attenuate a retroactive memory interference effect. Implications of these findings for exercise to improve memory and attenuate memory decay are discussed.
Alfred Schutz and ethnomethodology: Origins and departures
Authors: Hammersley Martyn
Published: July 2019

The work of Alfred Schutz was an important early influence on Harold Garfinkel and therefore on the development of ethnomethodology. In this article, I try to clarify what Garfinkel drew from Schutz, as well as what he did not take from him, specifically as regards the task of social inquiry. This is done by focusing in detail on one of Schutz’s key articles: ‘Concept and Theory Formation in the Social Sciences’. The aim is thereby to illuminate the relationship between Schutz’s views on the character of social science and Garfinkel’s radical proposal for a re-specified focus of investigation. This is further pursued by examining an important debate about the link between Schutz and ethnomethodology.
Psychopathologies of time: Defining mental illness in early 20th-century psychiatry
Authors: Fryxell Allegra R. P.
Published: July 2019

This article examines the role of time as a methodological tool and pathological focus of clinical psychiatry and psychology in the first half of the 20th century. Contextualizing ‘psychopathologies of time’ developed by practitioners in Europe and North America with reference to the temporal theories implicit in Freudian psychoanalysis and Henri Bergson’s philosophy of durée, it illuminates how depression, schizophrenia, and other mental disorders such as obsessive-compulsive behaviours and aphasia were understood to be symptomatic of an altered or disturbed ‘time-sense’. Drawing upon a model of temporal synthesis whereby in healthy individuals, a subjective temporal sense ( Ichzeit, durée, or personal lifetime) was perceived and understood in relation to objective time frameworks ( Weltzeit, clock-time, or quantitative time models like historical chronology), clinicians argued that mentally ill patients were unable to synthesize Ichzeit and Weltzeit, using variations in this disturbance to define specific pathological conditions.
Optimal sensor placement based on multiattribute decision-making considering the common cause failure
Authors: Feng Tao , Duan Rongxing , Lin Yanni , Zeng Yining
Published: July 2019

A new optimal sensor placement is developed to improve the efficiency of fault diagnosis based on multiattribute decision-making considering the common cause failure. The optimal placement scheme is selected based on the reliability of the top event on condition that the number of sensors is preset. Specifically, a β-factor model is introduced to deal with the common cause failure, and dynamic fault tree is used to describe the dynamic failure behaviors. Besides, a dynamic fault tree is converted into a dynamic Bayesian network to calculate the reliability parameters, which construct the decision matrix. Furthermore, an efficient TOPSIS algorithm is adopted to determine the potential locations of sensors. In addition, a diagnostic sensor model is developed to take into account the failure sequence between a sensor and a component using a priority AND gate, and the failure probability of the top event for all sensor placement scenarios is calculated to determine the optimal sensor placement. Finally, a case is provided to prove that the common cause failure has made a considerable impact on the sensor placement.
Mathematical modeling of a fractionally damped nonlinear nanobeam via nonlocal continuum approach
Authors: Jha Abhishek Kumar , Dasgupta Sovan Sundar
Published: July 2019

Modeling of fractionally damped nanostructure is extremely important because of its inherent ability to capture the memory and hereditary effect of several viscoelastic materials extensively used in nanotechnology. The nonlinear free vibration characteristics of a simply-supported nanobeam with fractional-order derivative damping via nonlocal continuum theory are studied in this article. Using Newton’s second law, the equation of motion for the nanobeam embedded in a viscoelastic matrix is derived. The Galerkin method is employed to transform the integro-partial differential equation of motion into a Duffing-type nonlinear ordinary differential equation. The fractional-order damping term is replaced by a combination of linear damping and linear stiffness term. The approximate analytical solution obtained via method of averaging is found to be in good agreement with solution obtained through numerical scheme. Detailed study of system parameters reveals that the fractional-order derivative damping has significant influence on the time response and effective natural frequency of the nanobeam.
‘The only safe haven of refuge in all the world’: Paris, Indian ‘revolutionaries’ and imperial rivalry, c. 1905–40
Authors: Marsh Kate
Published: July 2019

Focusing on British Indian subjects who travelled to France in the early twentieth century and who resided in Paris, this article argues that these migrants occupied a position that was simultaneously privileged and invidious. It urges that closer attention be paid to the group for two reasons. First, British Indians in Paris were able to negotiate contentious and potentially hazardous political situations according to context and audience, sometimes mobilising their status as British subjects as a means of achieving limited preferential treatment from the French state, at other times making use of a certain conception of Frenchness to garner support among socialist and anti-imperial movements. Second, the policing of the group reveals collaboration and competition between imperial nation-states and between different anti-colonial movements, analysis of which can nuance the growing body of historical research on the policing of foreigners and colonial subjects in Europe.
Camara Laye et J. M. G Le Clézio dans la quête épistémologique de la nature par le mythe d’origine
Authors: Simpore Karim
Published: July 2019

« Écrire, c’est rêver. Là-bas, quand on arriverait à Onitsha, tout serait diffèrent, tout serait facile. Il y aurait les grandes plaines d’herbes que Geoffroy avait décrites, les arbres si hauts, et le fleuve si large qu’on pourrait croire la mer, l’horizon se perdant dans les mirages de l’eau et du ciel » (Le Clézio, 1991 : 31). Ces propos extraits de Onitsha du Nobel de Littérature de 2008, inscrivent l’écologie au cœur de l’œuvre de l’auteur. Parallèlement, un autre auteur, Camara Laye, conscient des rapports étroits qui existent entre la nature et la sagesse africaine, ne manqué pas de fournir un autre paradigme du rêve de l’homme africain dans le roman, L’Enfant noir (1966). Au-delà donc des aspects narratifs de ces deux romans, il s’agira dans cet article de chercher à comprendre l’importance de l’interaction des éléments de la nature dans une perspective de la quête de soi et de celle du milieu environnant.
J. M. G. Le Clézio and Gérard Gouesbet’s cosmic, ecocentric framework for understanding the nature of human violence
Authors: Moser Keith
Published: July 2019

This study investigates the highly original theories about the origins of human violence developed by the physicist Gérard Gouesbet and the Franco-Mauritian writer J. M. G. Le Clézio. Both authors pinpoint the indifferent, cosmic forces that conceived all life as the hidden source of human aggression. In Violences de la nature and Terra Amata, Gouesbet and Le Clézio assert that the very act of existence itself is a violent struggle for survival. Although this biological parasitism is unavoidable due to the universal principles that govern life, both writers urge global society to deviate from its current path. In their biocentric reflections related to the absurdity of the human condition, Gouesbet and Le Clézio contend that we must find a way to end this ‘world war’ and to limit our incessant acts of aggression against the remainder of the cosmos.
Influences of wear-ring clearance leakage on performance of a small-scale pump-turbine
Authors: Yan Jianru , Zuo Zhitao , Guo Wenbin , Hou Hucan , Zhou Xin , Chen Haisheng
Published: July 2019

Wear-ring clearance leakage would affect performance of pump-turbine significantly. In this paper, the variation of the leakage and efficiency of flat ring seal and labyrinth seal are numerically studied on one pump-turbine when the width of clearance is 0.2 mm and 0.5 mm. The result shows that the effect of leakage flow cannot be neglected. The pump-turbine performance affected by leakage in turbine mode is more than that in pump mode at the same sealing structure and width of clearance. Each component’s proportion of total pressure loss hardly varies with flow rate at pump mode, which is opposite to that at turbine mode. Leakage does not change proportionally with system flow rate. When the width of clearance decreases to 0.2 mm, the leakage is reduced obviously because the maximum entropy occurs in the front pump chamber. The mixing of leakage flow and mainstream at impeller inlet at pump mode will increase the total pressure and decrease the flow angle and relative flow angle. Finally, it reduces the impeller’s work capacity.
Complex medical history of a patient with a compound heterozygous mutation in C1QC
Authors: Lubbers R , Beaart-van de Voorde L J J , van Leeuwen K , de Boer M , Gelderman K A , van den Berg M J , Ketel A G , Simon A , de Ree J , Huizinga T W J , Steup-Beekman G M , Trouw L A
Published: July 2019

Introduction

C1q is an essential part of the classical pathway of complement activation. Genetic deficiencies, caused by homozygous mutations in one of the C1q genes, are rare and are strongly associated with development of systemic lupus erythematosus (SLE). Here we describe a C1q-deficient patient with a compound heterozygous mutation.

Material and methods

Serum was analysed with enzyme-linked immunosorbent assay (ELISA) and Western blot for the presence of C1q, and DNA and RNA sequencing was performed to identify the mutations and confirm that these were located on different chromosomes.

Results

The medical history of the patient includes SLE diagnosis at age 11 years with cerebral involvement at age 13, various infections, osteonecrosis and hemophagocytic syndrome. Using ELISA and Western blot, we confirmed the absence of C1q in the serum of the patient. Using DNA sequencing, two mutations in the C1QC gene were identified: c.100G > A p.(Gly34Arg) and c.205C > T p.(Arg69X). With RNA sequencing we confirmed that the mutations are located on different chromosomes.

Discussion

The patient described in this case report has a compound heterozygous mutation in C1QC resulting in C1q deficiency.
A new joint screening method for right-censored time-to-event data with ultra-high dimensional covariates
Authors: Liu Yi , Chen Xiaolin , Li Gang
Published: July 2019

In an ultra-high dimensional setting with a huge number of covariates, variable screening is useful for dimension reduction before applying a more refined method for model selection and statistical analysis. This paper proposes a new sure joint screening procedure for right-censored time-to-event data based on a sparsity-restricted semiparametric accelerated failure time model. Our method, referred to as Buckley-James assisted sure screening (BJASS), consists of an initial screening step using a sparsity-restricted least-squares estimate based on a synthetic time variable and a refinement screening step using a sparsity-restricted least-squares estimate with the Buckley-James imputed event times. The refinement step may be repeated several times to obtain more stable results. We show that with any fixed number of refinement steps, the BJASS procedure retains all important variables with probability tending to 1. Simulation results are presented to illustrate its performance in comparison with some marginal screening methods. Real data examples are provided using a diffuse large-B-cell lymphoma (DLBCL) data and a breast cancer data. We have implemented the BJASS method using Matlab and made it available to readers through Github https://github.com/yiucla/BJASS .
Bootstrap confidence intervals for the optimal cutoff point to bisect estimated probabilities from logistic regression
Authors: Zhang Zheng , Shi Xianjun , Xiang Xiaogang , Wang Chengyong , Xiao Shiwu , Su Xiaogang
Published: July 2019

To classify estimated probabilities from a logistic regression model into two groups (e.g., yes or no, disease or no disease), the optimal cutoff point or threshold is crucial. While various methods have been proposed for estimating such a threshold, statistical inference is not generally available. To tackle this issue, we put forward several bootstrap based methods, including the conventional nonparametric bootstrap standard errors and the quantile interval. Special emphasis is placed on a more precise bagging estimator of the optimal cutoff point, for which a confidence interval can be obtained via the recently proposed infinitesimal jackknife method. We investigate the empirical performance of the proposed methods by simulation and illustrate their use via the analysis of a fertility data set concerning seminal quality prediction.
Scientific truth or debate: On the link between perceived scientific consensus and belief in anthropogenic climate change
Authors: Bertoldo Raquel , Mays Claire , Böhm Gisela , Poortinga Wouter , Poumadère Marc , Tvinnereim Endre , Arnold Annika , Steentjes Katharine , Pidgeon Nick
Published: July 2019

Scientists overwhelmingly agree that climate change exists and is caused by human activity. It has been argued that communicating the consensus can counter climate scepticism, given that perceived scientific consensus is a major factor predicting public belief that climate change is anthropogenic. However, individuals may hold different models of science, potentially affecting their interpretation of scientific consensus. Using representative surveys in the United Kingdom, France, Germany and Norway, we assessed whether the relationship between perceived scientific consensus and belief in anthropogenic climate change is conditioned by a person’s viewing science as ‘the search for truth’ or as ‘debate’. Results show that perceived scientific consensus is higher among climate change believers and moreover, significantly predicts belief in anthropogenic climate change. This relationship is stronger among people holding a model of science as the ‘search for truth’. These results help to disentangle the effect of implicit epistemological assumptions underlying the public understanding of the climate change debate.
Fewer Islets Survive from a First Transplant than a Second Transplant: Evaluation of Repeated Intraportal Islet Transplantation in Mice
Authors: Liljebäck Hanna , Quach My , Carlsson Per-Ola , Lau Joey
Published: July 2019

Beta cell replacement is an exciting field where new beta cell sources and alternative sites are widely explored. The liver has been the implantation site of choice in the clinic since the advent of islet transplantation. However, in most cases, repeated islet transplantation is needed to achieve normoglycemia in diabetic recipients. This study aimed to investigate whether there are differences in islet survival and engraftment between a first and a second transplantation, performed 1 week apart, to the liver. C57BL/6 mice were accordingly transplanted twice with an initial infusion of syngeneic islets expressing green fluorescent protein (GFP). The second islet transplant was performed 1 week later and consisted of islets isolated from non-GFP C57BL/6-mice. Animals were sacrificed either 1 day or 1 month after the second transplantation. A control group received a saline infusion instead of GFP-expressing islets, 1 week later obtained a standard non-GFP islet transplant, and was subsequently sacrificed 1 month later. Islet engraftment in the liver was assessed by immunohistochemistry and serum was analyzed for angiogenic factors induced by the first islet transplantation. Almost 70% of islets found in the liver following repeated islet transplantation originated from the second transplantation. The vascular density in the transplanted non-GFP-expressing islets did not differ depending on whether their transplantation was preceded by a primary islet transplantation or saline administration only nor did angiogenic factors in serum prior to the transplantation of non-GFP islets differ between animals that had received a previous islet transplantation or a saline infusion. We conclude that first islet transplantation creates, by unknown mechanisms, favorable conditions for the survival of a second transplant to the liver.
Evolution of Dada Uttam Kumar: Performing Masculinity and the Disillusioned Bhadralok Mahanayak in the 1970s’ Popular Melodramas
Authors: Banerjee Smita
Published: July 2019

This essay focuses on a fragment of the Bengali superstar Uttam Kumar’s star text, the dada figure, to analyse the contours of melodramatic enunciations and masculinity that appear in the 1970s’ popular films. This decade is identified with the radical politics associated with the Naxal movement that erupted in varied expressions of rage and anger at institutional and systemic failures. Since Uttam typified a bhadralok masculine subjectivity, his evolution in domestic melodramas especially in male weepies from the period enables me to read the specifics of regional cinema and its response to social and political contexts of the times.
Rubric Development and Validation for Assessing Comprehensive Internationalization in Higher Education
Authors: Mace Melissa K. , Pearl Denise
Published: July 2019

The purpose of this study was to determine if the Institutional Assessment Rubric on Comprehensive Internationalization in Higher Education could be developed and validated following Gehlbach and Brinkworth’s recommended steps for rubric development and validation. Utilizing a mixed-methods research design, 13 research participants evaluated and scored rubric cell descriptors over three survey rounds resulting in a rubric with a scale-level content validity index score ( S-CVI/Ave) of 0.920, well above the 0.80 acceptable minimum score. This mixed-methods rubric validation research study explains the process and results of a rubric developed for institutions interested in the comprehensive internationalization of their campuses and provides a scale to (a) conduct a baseline assessment; (b) develop a plan, establish goals, and align resources; and (c) track progress toward those goals over time.
Determinants of Self-Care in Patients With Heart Failure: Observations From a Developing Country in the Middle East
Authors: Massouh Angela , Abu Saad Huijer Huda , Meek Paula , Skouri Hadi
Published: July 2019

Introduction: Self-care is recognized as a means for improving outcomes of heart failure (HF), yet studies have not addressed what predicts successful self-care in collectivist cultures like Lebanon. Methodology: Self-care was measured, using the Arabic Self-Care of HF index, in 100 participants with HF (76% males; mean age 67.59) recruited from a tertiary medical center. Results: Self-care was suboptimal, with mean scores of 67.26, 66.96, and 69.5 for self-care maintenance, management, and confidence. Better HF knowledge, social support, and self-care confidence and lower New York Heart Association score predicted better self-care maintenance. Better knowledge, social support, and self-care maintenance, no recent hospitalization, and being unemployed predicted better self-care confidence. Better self-care confidence, maintenance, and HF knowledge predicted better self-care management. Discussion: HF self-care in Lebanon is suboptimal. Nurses need to identify facilitators of and barriers to self-care particular to this population. Interventions targeting HF knowledge, confidence, and caregiver support are expected to improve self-care in Lebanese patients.
East Meets West: Five Decades of Practice Research in Hong Kong
Authors: Chan T. M. S. , Sim T.
Published: July 2019

A review of social work practice research in Hong Kong identified 969 articles published over 50 years. Four main areas of their content were analyzed: (a) authorship, (b) practice area, (c) target clientele, and (d) research method. Our results showed that academics had produced most of the research publications (81%). The most common practice areas were children and youth (20%), mental health (19%), family (19%), and the elderly (11%). Youth (22%), the elderly (14%), and family and parents (14%) were the top three client groups. The majority of the methods (47%) used were quantitative, comprising mostly correlational methods (41%). The future development of Hong Kong’s social work practice research should build on current achievements and promote more practitioner–researcher collaboration.
Bleeding Symptoms and von Willebrand Factor Levels: 30-Year Experience in a Tertiary Care Center
Authors: Moonla Chatphatai , Akkawat Benjaporn , Kittikalayawong Yaowaree , Sukperm Autcharaporn , Meesanun Mukmanee , Uaprasert Noppacharn , Sosothikul Darintr , Rojnuckarin Ponlapat
Published: July 2019

Correlations between bleeding symptoms and von Willebrand factor (VWF) levels may help to predict hemorrhagic severity in the Westerners with von Willebrand disease (VWD), but data in Asians are lacking. In this study, Thai patients with VWF levels <50 IU/dL without any secondary causes were enrolled from 1988 to 2018 to determine the relationship between VWF levels and hemorrhagic manifestations. According to the current concept, we reclassified VWD and low VWF by VWF levels ≤30 and 30 to 50 IU/dL, respectively. Type 2 VWD was diagnosed if VWF activity to antigen ratio was ≤0.6. Bleeding severity was determined by the condensed MCMDM-1VWD bleeding score (BS). Among 83 patients, VWF activities showed negative correlations with BS ( P = .001), which were higher in type 2 (median: 7, interquartile range [IQR]: 5-11) compared with type 1 VWD (median: 3, IQR: 2-4) and low VWF (median: 4, IQR: 2-8). Bleeding symptoms were indistinguishable between type 1 VWD and low VWF using the 30 IU/dL cutoff point. However, VWF ristocetin cofactor activity or gain-of-function mutant glycoprotein Ib binding activity <36.5 IU/dL and VWF collagen binding activity <34.5 IU/dL could predict increased bleeding risk (BS ≥3) by 92.3% specificity and 70.0% sensitivity ( P < .0001).
A novel method for force identification based on filter and FEM
Authors: Zheng Zhanpeng , Wu Chengjun , Wang Donghong
Published: July 2019

Force identification plays a vital role in vibration control and structural health monitoring. Force identification is an inverse problem to determine the excitation load from the responses. In general, the inverse problem has strong ill-posedness and ill-condition, especially in the case of low signal-to-noise ratio. Singular value decomposition and Tikhonov regularization are widely used for the reconstruction of the input force. Nevertheless, the anti-noise performance and accuracy of the two methods are still unsatisfactory. In this paper, we present a novel method for force identification based on a filter and the finite element method (FEM). The filter is used to suppress the noise of the input signals. FEM is introduced to reduce the discretization error and the regularization parameters are optimized by the genetic algorithm. After the signal is filtered, the characteristics of the signal will be changed. Especially, the initial and the last segments of the input signal will be lost. These changes may make the identified force inaccurate, even more inaccurate than the force identified with no filtering. To deal with this problem, cubic spline interpolation and a nonlinear autoregressive neural network are introduced to repair the input signals. Finally, three numerical examples and experiments are used to verify the superiority of the method.
Vibration control mechanism of the metabarrier under train load via numerical simulation
Authors: Zhao Caiyou , Wang Liuchong , Liu Dongya , Gao Xing , Sheng Xi , Ping Wang
Published: July 2019

The problem of ambient vibration caused by rail transit continues to grow, and control effect requirements of different vibration reduction measures are always increasing. A new kind of vibration isolator used for floating slab tracks (FST) has been developed, called a metabarrier. Based on the bandgap properties of phononic crystals, it can realize a better vibration reduction capacity in certain frequency ranges with the same vertical stiffness as the original device. In order to study the vibration reduction characteristics of metabarriers under actual train loading action, two vibration isolators—a steel-spring vibration isolator and a metabarrier—were used to establish a train–FST–substrate dynamic coupling model. This study shows that the reduction capacity influenced by the phononic crystal bandgap is stable under different train speeds. In addition, under train load, the metabarrier can be used not only to isolate vibration by means of the bandgap, but also to absorb vibration dynamically, further expanding the vibration reduction frequency range. With optimized frequency range, metabarriers can reduce the acceleration vibration level by more than 9 dB over steel-spring vibration isolators.
Defining the Enemy: How Donald Trump Frames the News Media
Authors: Meeks Lindsey
Published: July 2019

Donald Trump has been a vocal critic of the news media. This study content analyzes how Trump tweeted about the news media as the Republican nominee through his first year in office. Results revealed that Trump privileged conservative media via praise and media appearance frames, mentions, and retweets, while denigrating nonconservative and general media via attack and bias frames. In addition, Trump employed attack frames more as president than nominee. Finally, Trump’s attack and bias frames generated more retweets and favorites than other frames. Given Trump’s influence, such framing could strongly contribute to the public’s polarized perceptions of the news media.
Tamoxifen-induced vasculitis
Authors: Kulkarni Utkarsha , Nayak Veena , Prabhu Mukhyaprana M , Rao Raghavendra
Published: July 2019

Introduction

Tamoxifen is a selective estrogen receptor modulator used widely for the treatment of breast cancer. Apart from its common adverse reactions such as endometrial cancer, deep vein thrombosis, pulmonary emboli, there are very few reports about its ability to cause vasculitis.

Case report

A 45-year-old woman who underwent modified radical mastectomy was started on tamoxifen. Six months later, she developed vasculitis which was confirmed by immunofluorescence-induced vasculitis in a pre-menopausal woman.

Management and outcome

Dapsone was used to relieve her symptoms for two weeks, but the lesions reappeared when dapsone was stopped. She continues to suffer from vasculitis as tamoxifen could not be discontinued.

Discussion

This case report is important in order to draw attention towards this rare, but equally severe side effect of cutaneous vasculitis due to the most commonly used drug for breast cancer. In view of the absence of alternative medications for pre-menopausal women, it is necessary to have a strict monitoring of its adverse effects as well as more intensive research for a better agent.
Apalutamide: A new agent in the management of prostate cancer
Authors: May Megan B , Glode Ashley E
Published: July 2019

Apalutamide is a competitive inhibitor of the androgen receptor and binds directly to the ligand-binding domain. The US Food and Drug Administration approved apalutamide on 14 February 2018 for use in patients with nonmetastatic castration-resistant prostate cancer based upon results from the phase III SPARTAN trial demonstrating significantly longer metastasis-free survival over placebo. The SPARTAN trial evaluated 1207 patients with nonmetastatic castration-resistant prostate cancer who were randomized 2:1 to apalutamide or placebo in combination with androgen deprivation therapy. Patients who received apalutamide experienced statistically significantly longer metastasis-free survival (40.5 versus 16.2 months, hazard ratio 0.28 (95% confidence interval = 0.23–0.35); P < 0.0001), which was the major efficacy outcome. Rash, hypothyroidism, and fracture were reported to occur more frequently with apalutamide than placebo. Based upon these results, apalutamide was deemed a safe and effective treatment option for patients with nonmetastatic castration-resistant prostate cancer. Clinical trials are ongoing to expand its indication in the metastatic setting, and identify additional roles for apalutamide in the management of prostate cancer such as in the castrate-sensitive metastatic setting.
Interfacial polyconvex energy-enhanced evolutionary model for shape memory alloys
Authors: Frost Miroslav , Kružík Martin , Valdman Jan
Published: July 2019

A sharp-interface model describing static equilibrium configurations of shape memory alloys by means of interfacial polyconvex energy density introduced by Šilhavý and extended to a quasistatic situation by Knüpfer and Kružík is computationally tested. Elastic properties of variants of martensite and the austenite are described by polyconvex energy density functions. Volume fractions of particular variants are modeled by a map of bounded variation. In addition, energy stored in martensite–martensite and austenite–martensite interfaces is measured by an interface-polyconvex function. It is assumed that transformations between material variants are accompanied by energy dissipation, which, in our case, is positively one-homogeneous giving rise to a rate-independent model. Various two-dimensional computational examples are presented and the computer code used is made available for download.
On the dependence of standard and gradient elastic material constants on a field of defects
Authors: Solyaev Yury , Lurie Sergey , Barchiesi Emilio , Placidi Luca
Published: July 2019

In this work, we consider a strain gradient elasticity theory with an extended number of field variables: the displacement vector and an additional scalar field defining the internal micro-deformation. The total internal energy of the model depends on the strain, the micro-deformation function, their gradients, and the coupling. The considered model can be treated as gradient/micromorphic. Moreover, the micro-deformation field can be treated as a field of scalar defects distributed along the medium. Based on analytic (one-dimensional) solutions of uniform/non-uniform deformation of the rod, we introduce (i) an apparent stiffness and (ii) an apparent length scale parameter. Subsequently, we provide a variant of continuum-on-continuum homogenization by equating tip displacements for the gradient/micromorphic medium and an equivalent strain gradient one. Elongation of the gradient/micromorphic rod is therefore equated with the corresponding elongation of the equivalent strain gradient rod, whose behavior is characterized by the apparent material constants. Subsequently, the non-dimensional coupling number is identified with a damage parameter. It is shown that, on the one hand, the apparent stiffness of the rod is reduced when such parameter increases. On the other hand, the apparent length scale parameter (i.e. the apparent second gradient elastic coefficient) increases when the damage parameter increases. Therefore, it is shown that the presence of defects in a second gradient linear elastic material may increase its apparent strain gradient behavior.
The Co-evolution of Organizational and Network Structure: The Role of Multilevel Mixing and Closure Mechanisms
Authors: Amati Viviana , Lomi Alessandro , Mascia Daniele , Pallotti Francesca
Published: July 2019

We present a dynamic multilevel framework for analyzing the mutual dependence of change in interorganizational networks and internal organizational structure. Change occurring at the former (interorganizational) level involves decisions to change the portfolio of network ties to external partners. Change occurring in the latter (intraorganizational) level involves decisions to change the portfolio of internal activities. We estimate a recently derived class of stochastic actor-oriented models (SAOMs) that we adopt and adapt to specify how decisions to change internal portfolios of activities and external portfolios of partners are connected by theoretically derived multilevel mechanisms that link organizational and network structures. We show that statistical models for multilevel networks reproduce with high fidelity the structural regularities observed in the distribution of (a) activities within organizations, (b) network ties between organizations, and (c) knowledge available in the organizational field. We discuss the implications of the study for theory development, and for empirical research on interorganizational and other kinds of multilevel networks.
Does radiopaque cement conceal periprosthetic bone loss around femoral stems?
Authors: Flatøy Bernhard , Dahl Jon , Röhrl Stephan Maximilian , Nordsletten Lars
Published: July 2019

Background:

Periprosthetic bone remodelling may increase fracture risk and deplete bone stock around hip implants. These changes are in part caused by implant design, advocating an early evaluation of bone remodelling properties of new implants. This can be done by repeated dual-energy x-ray absorptiometry (DXA) measurements. We know that radiopaque cement falsely elevates bone mineral density (BMD) in single measurements, however, its impact on repeated measurements, i.e. BMD changes is unexplored. We have therefore investigated whether the presence of radiopaque cement affect repeated BMD measurements.

Methods:

33 patients eligible for total hip replacement were randomly assigned to either radiopaque or radiolucent cement. BMD changes up to 12 months were measured by DXA, in addition to Harris Hip Score, plain radiographs and radiostereometric analysis (RSA).

Results:

Periprosthetic BMD declined during the first 3–6 months in all zones in both groups. The greatest reduction (14%) was seen in the proximal Gruen zones (1 and 7). We found a significant difference in Gruen zones 1 and 2, where the measured bone loss was higher in the radiolucent cement group.

Conclusions:

The presence of radiopaque agents in bone cement may influence DXA measurements of bone remodelling. ClinicalTrials.gov identifier NCT00473421.