bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Private Pension Provision in the Conditions of Reforming the Pension System of Ukraine
Authors:   Podillya State Agrarian and Engineering University, Rudyk V. K.
Published: January 2022

The efficient functioning of the non-state pension system, which forms the third level of the domestic pension system, is essential for increasing the incomes of citizens of retirement age. The article is aimed at defining the main ways of further development of the non-state pension system in the context of reforming the national pension system, creating favorable conditions for attracting an increasing number of the population to participate in voluntary accumulation pension programs. The article provides an assessment of the status of the non-state pension system in Ukraine, analyzes its main indicators for the last three years. The results of the study showed that today voluntary accumulation pension programs, which form the basis of the system of non-state pension provision, are not popular among the population. The main challenges and factors that hinder its development in our country are determined. The main directions of development of the system of non-state pension provision for the near future are proposed. Particular attention is paid to the expediency of introducing the tax-free voluntary automatic individual savings pension accounts in banks. Among the priorities for improving the functioning of the third level, an important place is to find ways to further develop the non-state pension funds (NSPFs), among which an increase in their reliability is to be highlighted. To assess the reliability of NSPFs as a socio-economic system, it is necessary to analyze such parameters as: presence of public trust in the fund; the fund’s ability to cash payments; financial condition of the fund. It is proved that the improvement of the legislative framework of the third level of the domestic pension system should ensure the protection of property rights and interests of participants in the non-state pension provision, as well as ordering the taxation of participants in the accumulation pension system. An extremely important direction for the further development of the third level of the national pension system is the reduction and optimization of the costs of administering individual pension accounts of participants in the accumulation pension programs.
Problems of Audit Development and Audit Reform in Ukraine
Authors:   V. N. Karazin Kharkiv National University, Sliunina T. L. , Matiushko M. M. ,   V. N. Karazin Kharkiv National University
Published: January 2022

In the context of the development of the market economy and the reform of accounting in accordance with international standards, auditing activity in Ukraine is becoming widespread. The issue of the quality of audit activity is currently of high relevance. Despite the fact that today the audit regulation system seems to be fully established, there are a number of problems that complicate the process of regulating the audit market entities. Therefore, the purpose of the research is to analyze the updated requirements for regulating audit activities along with problems of audit development in Ukraine. In the course of the research, it was found that the audit serves as a reliable way to justify the financial statements data and is one of the important types of services. At the same time, it is defined that the audit activity currently has a number of contradictions and problems. The article discusses the main aspects of audit regulation in Ukraine, peculiarities of the current state of the audit market, as well as prospects for the regulation of audit activity in Ukraine. The essence of the audit, features of its methodology and organization, its importance for the development of the State economy, the need for its research and reform are determined. The current state of the market of audit services, the normative legal acts regulating the issues of auditing activity and attestation of auditors, the results of control over the quality of work of auditors and audit organizations are researched. An analysis of the market of audit services in Ukraine was carried out. The impact of current changes in the legislation regulating the audit on the state of auditing activity is examined. Other major problems that arose and arise on the way of development of audit activity during its formation in Ukraine are researched, the reasons for their occurrence are identified. The need to solve many problems and carry out significant reforms related to audit activities in Ukraine is determined.
Sustainable Behavior in International Business: Corporate Social Responsibility for Mimicry or for Business Value?
Authors:   National Technical University «Kharkiv Polytechnic Institute», Zubkova A. B. , Makarenko A. B. ,   National Technical University «Kharkiv Polytechnic Institute», Misiunia R. M. ,   National Technical University «Kharkiv Polytechnic Institute», Maihurova D. S. ,   National Technical University «Kharkiv Polytechnic Institute», Vodiakhina M. O. ,   National Technical University «Kharkiv Polytechnic Institute», Ihnatova A. A. ,   National Technical University «Kharkiv Polytechnic Institute»
Published: January 2022

The paper is aimed at studying different pillars for the development of long-term and short-term strategies in the field of sustainable development and corporate social responsibility. The paper underlines the key differences between the concepts of sustainable development, corporate social responsibility, and ecological, social, and corporate governance. The study aims to highlight the key differences between sustainable behavior and mimicry, i.e. masking the results of companies' activity under the global or local trends in corporate social responsibility. The article focuses on studying key systems for measuring the sustainable development level. Therefore, the results of the world's leading companies have been analyzed according to the main ratings of the sustainable development level. The paper presents the empirical study of the activities of the leading Ukrainian companies in sustainable development, compares their results with those of less successful companies, examines the general situation in Ukraine. Despite the relatively high sustainable development level of the leading players in the Ukrainian market, the companies that had a lower position in the sustainability ranking got lower scores by the key components of evaluating the sustainability level. The research emphasizes the complexity of measuring the sustainable development level of enterprises, and also proposes an integrated system for evaluating the sustainable development level of enterprise, based on a combined list of components used by different analytical companies. The expediency of a more detailed monitoring of the Ukrainian companies’ activity, aiming at detecting and counteracting mimicry, is substantiated. The paper proves the necessity to develop a comprehensive measurement system for determining the sustainable development level, which will provide the most accurate evaluation and recommendations for business development.
A Study of Chinese learners’ Beliefs, Strategy use and Proficiency in Learning Chinese as a Foreign Language
Authors: Umeanowai Kingsley Obiajulu , Lei Wang
Published: January 2022

This research is a mixed-methods study that examined Chinese learners' beliefs and strategies used in language learning in the context of their achieved proficiency. To investigate the relationship existing between these variables, two survey questionnaires, a Chinese proficiency test (Hanyu Shuiping Kaoshi: HSK 4), and an interview item were constructed. In total, one hundred and twenty international students were conveniently sampled for the BALLI and SILL questionnaires, as well as a Proficiency Test, and six out of the one hundred and twenty were selected to respond to the interview. The results revealed that learning beliefs about learning and communication strategies and metacognitive strategies in learning strategies were frequently used among these participants. The study also showed that a strong positive correlation exists between learning beliefs and the strategies used, while a weak positive and statistically significant correlation exists between their Chinese proficiency, learning beliefs about the language, and the strategies used. However, the regression analysis conducted showed that the regression model is statistically significant (F=70.63, p<0.05), indicating that the beliefs and strategies used have the potential to statistically predict their learning proficiency. The study concluded with suggestions on how to address negative learning beliefs and build adequate learning strategies to improve their Chinese proficiency.
Vocabulary Learning Strategies Frequently Used by Sudanese EFL Learners at the Tertiary Level to Strengthen their Vocabulary Knowledge
Authors: Ibrahim AbdulMahmoud , Alshami Hassan
Published: January 2022

The study aimed to find out the most frequent Vocabulary Learning Strategies (VLSs) that had been used by the Sudanese EFL learners at the Faculty of Education, Alzaiem Alazhari University. A (VLSs) questionnaire was designed and handled to 159 EFL learners in 1st year. The questionnaire adopted Schmitt’s (1997) taxonomy with slight changes of items. There was a significant agreement among them in using vocabulary learning strategies to expand their vocabulary. Cognitive and memory strategies were the most frequently used, while social was the least used. The study recommended that teachers can help their students to become initiative and take responsibility for their success by providing them with a sense of what vocabulary learning strategies are, to enhance their vocabulary knowledge. Moreover, teachers should present a wide range of (VLSs) to their students for both a classroom-related setting and self-directed vocabulary learning.
Ciberacoso en jóvenes de bachillerato: ¿quiénes participan más, los hombres o las mujeres?
Authors: Serrano Barquín Carolina , Morales Reynoso Tania , Mendoza González Brenda
Published: January 2022

El ciberbullying es un comportamiento agresivo que ocurre en ambientes virtuales, que usa las tecnologías de la información y la comunicación (TIC) como la principal herramienta para lastimar a otras personas, exponiendo a las víctimas ante una audiencia que con su silencio hace legítimas las agresiones. El objetivo general de la investigación es conocer si existen diferencias entre hombres y mujeres en su participación como perpetradores o víctimas en ciberbullying. Es una investigación cuantitativa, con estudio descriptivo y diseño no experimental, transversal. Participaron 252 estudiantes de una institución pública de bachillerato en el Estado de México, 129 mujeres (51%) y 123 hombres (49%). Se aplicó un instrumento que mide la variable ciberbullying; el instrumento fue aplicado en línea. Los resultados permiten responder a las preguntas de investigación planteadas, identificándose que tanto hombres y mujeres se encuentran en el mismo riesgo de ser víctimas y ser agresores en ciberbullying. Se discuten los resultados con base en una perspectiva ecológica al identificarse aspectos sociales como acceso a internet por género, niveles de violencia en el país y motivación para ejercer ciberbullying.
ЧИ ВАРТО СТАВИТИ ЗАПИТАННЯ ГОЛОСАМ З МИНУЛОГО?
Authors: Vradii Yehor
Published: January 2022

Рецензія на книгу Омера Бартова «Анатомія геноциду: життя і смерть міста, що називалося Бучач»
Design and Development Key Board For Aksara Bali On Android With Auto Parts Improvement
Authors: Iswara Ida Bagus Ary Indra , Santika Putu Praba , Wijaya I Nyoman Saputra Wahyu
Published: January 2022

Balinese is used as a natural language used in daily life in the islands of Bali, given the importance of preserving Balinese, the provincial government of Bali has tried to preserve Balinese in various ways, one of which is by issuing a Balinese Governor Regulation. Not only the government is trying to preserve Balinese language and script, some people are also trying to preserve it. The inclusion of Balinese script in Unicode makes it very easy to display Balinese script in various media. Balinese script is unique in the number of letters used. In this study, the device will be developed to enter in the form of a keyboard or keyboard and an application called Tamiang to facilitate users in typing and using the Balinese script on a computer device. The layout of the buttons on Tamiang are arranged according to the level of use of each character. Tamiang has only been developed on computer devices with multiplatform concepts. Along with technological developments, the computer device in this study will be developed Tamiang application on the Android platform. So that it can facilitate anyone in accessing and learning the Balinese language.
Sistem Informasi Administrasi Pembayaran SPP Pada SD PGRI Kota Denpasar
Authors: Wirayanti Ni Putu Eka , Sugiartawan Putu , Suryawan I Wayan Dharma
Published: January 2022

Abstract. The development of information technology is currently running rapidly to reach all fields, one of which is in the field of education. In educational institutions, it requires good management of data management to meet student needs. The administrative payment system in the field of education is very important to record student administration payment payments at the school. Accuracy and accuracy in the payment system are the main factors in obtaining effective and efficient results. With the use of these computers, will make it easier to process data and is very influential in work effectiveness. So the existence of information technology is a means to facilitate the community in managing data and presenting information in an educational institution. To solve this problem, it is necessary to have the right solution in the form of an administrative information system at SD PGRI Denpasar City. The use of this information system will have a positive impact in carrying out administration and make it easier for 2 staff employees to enter the names of students, then be able to record anyone who has not or is late in paying the tuition fee. Based on the description, the title of the research to be made is the Design of Administrative Information Systems at SD PGRI Denpasar City Based on a Website.
Rancang Bangun Sistem Informasi Akuntansi Di Stiki Copy Center
Authors: Haris Lucky Hardiyanti Kartika , Ardiana Dewa Putu Yudhi , Udayana I Putu Agus Eka Darma
Published: January 2022

Abstract STIKI Copy Center is one place of business that provides print, copy, scan and sells office stationery services. Financial reporting process that occurs in STIKI Copy Center is still not in accordance with the financial statements should be and still use Ms.Excel which makes the owner feel difficulty in the process of calculating the current formula. The financial statements made at Ms.Excel can be manipulated by someone or the owner can do inputting with the same data so that it can cause redundancy and can also cause incompatibility of data and data that could be lost or deleted if infected by a virus or accidentally deleted.

This research aims to design and build an accounting information system at STIKI Copy Center which begins with the stages of identifying problems, conducting data collection, analyzing system modeling using UML, building systems using the laravel framework and MySQL database. The results of this research are financial applications based website that will process the transaction income and expenses and print reports general ledger, balance sheet, income statement, statement of changes in capital and is also equipped with a revenue graph for each month. From the test results by using black box testing can be seen that the system has been going well as expected
Роль міжнародної допомоги у відновленні роботи переміщених закладів вищої освіти: досвід СНУ ім. В. Даля
Authors: Поркуян О.В. , Семененко І.М.
Published: January 2022

Освіта є одним з основних прав людини, що закладає ба-зис для розвитку країни в цілому та її окремих регіонів. В Україні функціонують значна кількість закладів вищої освіти, які сприяють реалізації цього права. В Україні іс-нують переміщені заклади вищої освіти, які вимушено змінили місце свого розташування у 2014 році внаслідок збройного конфлікту. Вимушене переміщення закладів освіти суттєво вплинуло на сталість їх функціонування через втрату ними матеріально-технічної бази, кадрово-го потенціалу, вплив негативних чинників, як от близь-кість до лінії зіткнення, від’їзд населення з Донецької та Луганської областей тощо. Стаття спрямована на дос-лідження ролі міжнародної допомоги у відновленні робо-ти переміщених закладів вищої освіти, зокрема, на прик-ладі Східноукраїнського національного університету імені Володимира Даля (СНУ ім. В. Даля).

В статті зазначено, що переміщення закладів вищої освіти на нове місце було складним процесом, який міг су-проводжуватися конфліктами, утрудненою адаптацією тощо. Створена у 2016 році Рада ректорів переміщених закладів вищої освіти, як консультативно-дорадчий орган при Міністерстві освіти і науки України, сприяла підт-римці цих закладів та захисту прав учасників освітнього процесу. Проте найсуттєвішу підтримку відновленню функціонування надала міжнародна спільнота через різ-номанітні проєкти і програми допомоги.

Сьогодні СНУ ім. В. Даля, як і решта переміщених закла-дів вищої освіти, став повноцінним учасником регіональ-ного розвитку, осередком згуртованості і активного гро-мадянства, майданчиком для діалогу між різними регіо-нальними стейкхолдерами. Завдяки отриманню міжнаро-дної допомоги в університеті було створено різні майдан-чики і центри, діяльність яких сприяє розвитку м’яких на-вичок здобувачів, партнерству і співпраці з громадами, сталому розвитку регіону в цілому. При СНУ ім. В. Даля створено дві громадські організації, з якими за підтримки міжнародних організацій реалізовано суттєву кількість проєктів. В статті наведені приклади різних проєктів, що реалізовано СНУ ім. В. Даля, зокрема, відзначено про важливість поточного проєкту ЄС «Відродження пере-міщених університетів: посилення конкурентоспромож-ності, підтримка громад» (REDU), який спрямований на досягнення багатьох різнопланових цілей. На основі пред-ставлених проєктів, в статті узагальнено основні ре-зультати діяльності закладів вищої освіти, досягненню яких сприяє міжнародна підтримка.
Effect PCC Slab Curling and Warping on Pavement Roughness
Authors: Lee Hyung , Haider Syed , Chatti Karim , Buch Neeraj
Published: January 2022

Longitudinal profile measurements are vital for assessing the functional performance in terms of smoothness for new and existing pavements. However, the longitudinal profiles of Jointed Concrete Pavements (JCP) are significantly affected by temporal and diurnal changes that influence curling and warping of the concrete slabs. Therefore, consideration of such effect is essential for accurate assessment of pavement smoothness. The longitudinal profile measurements are commonly summarized by the International Roughness Index (IRI) that reduces the thousands of elevation values into a single value. However, no matter which index is calculated from a longitudinal profile, the quality of the information is only as good as the profile measurement. Thus, there is a need to evaluate the impacts of temporal (seasonal temperature/moisture and daily temperature) variations on longitudinal profile measurements, especially for JCPs. In this study, a new method is proposed for separating the curvature related IRI (i.e., due to curling and warping) from the non-curvature related IRI (i.e., due to other distresses such as spalling, faulting, etc). The level of curling and warping within each profile was summarized in terms of the Pseudo Strain Gradient (PSG). Examples from a couple of JCP sections indicated that temporal variations during a single day could have significant impacts on IRI. Results show that diurnal variations in PSG explained many of the changes in roughness over time. Such influence of seasonal and daily IRI variations can influence current practices—how highway agencies collect surface roughness for pavement management purposes and perform smoothness measurements for construction quality control.
Degradation Process of Doweled Transverse Joint of 30 Years Old Concrete Pavement on Expressway in Japan
Authors: Nishizawa Tatsuo , Takai Kenji , Noro Naofumi , Kurato Nobuhiro , Nakamura Yasuhiro
Published: January 2022

A section of jointed concrete pavement on Tokai-Hokuriku Expressway in the central region of Japan main island was opened in 1986. After 30 year service, small faulting has begun to appear at many joints. In order to grasp the entire situation of the joints, FWD tests were performed at transverse joints in 2011 and 2017, and the structural condition of each joints was evaluated from the results of the tests with a backcalculation method developed in this study. Some of the joints, which were judged to be severely damaged, were excavated to check the actual condition of the joint and validate the developed evaluation method. The evaluation on the joints of this particular concrete pavement revealed that the number of degraded joints has increased rapidly from 2011 to 2017, getting worse in recent years. Also, some backcalculation results imply that many dowels of the joints with the high load transfer efficiency and low deflections were corroded and some of them completely broke, and that a void formed underneath the joint.
Az önkontroll és a kockázatészlelés kapcsolata serdülők étkezési magatartásával és motivációikkal
Authors: Szabó Katalin , Pikó Bettina
Published: January 2022

Az egészségtelen táplálkozás okozta elhízás, és az ahhoz kapcsolódó betegségek súlyos népegészségügyi problémát jelentenek már a fiatalok körében is. A prevenció szempontjából nélkülözhetetlen a serdülők étkezési szokásainak, és az azokat befolyásoló tényezőknek a feltárása. Célunk serdülők étkezési magatartásának és motivációinak felmérése, valamint ezek önkontrollal és a táplálkozással kapcsolatos kockázatészleléssel való kapcsolatának felderítése volt. Kutatásunkban 374 szegedi és budapesti középiskolás vett részt (48% fiú, átlagéletkor: 16 év, szórás = 1,5). Az adatfelvételhez önkitöltős kérdőívet használtunk, amely a demográfiai kérdéseken kívül az étkezési magatartásra és motivációra vonatkozó, valamint a táplálkozással kapcsolatos kockázatészleléssel és az önkontroll felmérésével kapcsolatos állításokat tartalmazott. Faktoranalízissel csoportosítottuk az étkezési magatartást („junk ételek/italok fogyasztása”, „egészségorientált táp­lálkozás” és „nassolás és szokáson alapuló táplálkozás”), valamint az étkezési mo­tivációkat (társas, érzelmi és külső motiváció, tradíciók és belső motiváció és egészségmotiváció). A korrelációanalízis eredményei szerint az önkontroll pozitív kapcsolatban állt az egészségorientált magatartással és az egészségmotivációkkal, valamint ne­ga­tívan korrelált a társas, érzelmi és külső motivációkkal, illetve a „junk” ételek és italok fogyasztásával. Ez a két utóbbi együtt járt a nagyobb mértékű kockázatészleléssel is. Eredményeink felhívják a figyelmet arra, hogy az iskolai prevenciók kidolgozása során fokozott figyelmet kellene fordítani az önkontroll erősítésére és a kockázatészlelés és az étkezési motivációk szerepének feltárására.
100 éves az inzulin
Authors: Winkler Gábor
Published: January 2022

Százéves az inzulin. A tanulmány az évforduló kapcsán áttekinti az inzulinéra előtti és utáni időszak főbb eseményeit, a készítményválaszték bővülését és az inzulin alkalmazásával kapcsolatos főbb klinikai események kronológiáját. Kitér a használatával kapcsolatos eszközök, beadó tollak, inzulinpumpák, automatizált kezelési rendszerek történetére is. Rámutat, hogy noha az inzulinadagolás a hiányzó, vagy a szükséglethez képest elégtelen endogén hormontermelés kívülről történő pótlása, napjainkig a cukorbetegség legáltalánosabb, a betegség minden típusában és stádiumában alkalmazható formája.
Factores sociodemográficos y migratorios en la reintegración económica y social en Tijuana de los deportados mexicanos envejecidos
Authors: Santiago Vargas Alejandra , Alarcón Acosta Rafael , Calva Sánchez Luis Enrique
Published: January 2022

The massive deportation of Mexicans from the United States, including aging adults, has shocked the lives of millions of families. The main purpose of this article is to analyze the sociodemographic and migratory factors that influence the economic and social reintegration of aging deported Mexicans. For this purpose, a mixed methodology is used, combining descriptive statistics from the Survey on Migration in the Northern Border of Mexico with five semi-structured interviews about the life histories of older adults who now reside in Tijuana. The main findings of this study reveal that the longer the residence in the United States, the greater the legal consequences of deportation. In addition, strong social networks in both countries and command of the English language positively affect integration. On the other hand, advanced age, low educational attainment and a chronic disease such as diabetes hinder this process.
TELEVİZYON HABERLERİNDE HAVA OLAYLARI VE ETKİLERİ: METİN YAPISI VE ALTDİL
Authors: GÜVEN Mine
Published: January 2022

Bu çalışmada, hava koşullarının insan yaşamı ve fiziksel ortam üzerindeki etkilerini konu alan TV haber metinleri, konuya özgü bir altdil oluşup oluşmadığının belirlenmesi amacıyla nitel yöntemle çözümlenmiş olup metinlerin yapısı, kullanılan sözcüksel ve/veya dilbilgisel anlatım olanakları ve bunları biçimlendirmiş olabilecek kısıtlar saptanmaya çalışılmıştır. Çalışmanın veri tabanı, Eylül 2019- Şubat 2020 tarihleri arasında TRT Haber-İşitme Engelliler Haber Bülteni’nde yayınlanmış 27 adet haberden oluşmaktadır (toplam 1.845 saniye/352 birim/2.987 sözcük). Bu haberlerin, giriş ve gövde olmak üzere iki bölümden oluştuğu, giriş bölümünde haberin anahatlarının sıralandığı, gövdedeyse 5N1K (kim, ne, nerede, ne zaman, nasıl ve neden?) sorularının yanıtlandığı gözlemlenmiştir. Bu metin yapısı nedeniyle, bilgi yapısının girişte kısmen bozulduğu, dolayısıyla da aynı konuyu sürdürmeyi sağlayan özne görevindeki boş adılların görece olarak daha az sıklıkla kullanıldığı anlaşılmıştır. Gövdede konuya özgü sözcüksel ve/veya dilbilgisel yapıların görece sıklığının arttığı, çeşitli eşdizimli örüntülerin ve kalıplaşmış yapıların ortaya çıktığı saptanmıştır. Hava olayının hangi bölgede/yerleşim biriminde, hangi zaman diliminde, ne kadar sürdüğü; yağış durumunda, türü, şiddeti ve yere/zamana göre değişkenlik gösterip göstermediği öncelikle aktarılan bilgilerdir. Hava olayının gündelik yaşamı ve/veya fiziksel çevreyi hangi biçimde etkilediğinin anlatılması ise özellikle eylem-adöbeği eşdizimliliklerinin oluşması dolayısıyla daha kısıtlı bir söz dağarcığının kullanılmasına yol açmıştır. Ancak, sözdizimsel çeşitlilik bakımından genel dilden ayrışma veya görece yalınlaşma söz konusu değildir. Özgül bir anlamsal alana ait olup kısıtlı bir söz dağarcığı içermeleri nedeniyle, veri tabanındaki haber metinlerinde meteoroloji uzmanlık dilinden etkilenmiş bir altdil oluştuğu ileri sürülebilse de sözdizimsel çeşitlilik bakımından genel dil özellikleri gözlemlenmektedir. Bunun olası nedenleri arasında (i) TV haberlerinin genel izleyici kitlesince kolayca anlaşılır olmasının beklenmesi ve (ii) metinlerin yerleşik metin yapısı ve kurumun benimsediği haber söylemine uygun biçimde üretilmesi sayılabilir.
Implementation of the Gandoriah-Sunur Beach Tourism Destination Development Program as a Pariaman City Tourism Strategic Area (KSPK), West Sumatra Province, Indonesia
Authors: Fasdiah Nurul , Nurhascaryani Pratiwi , Rahmah Mutia
Published: January 2022

The Tourism and Culture Department has made a program to develop the Gandoriah-Sunur Beach tourism destination as a Pariaman City Tourism Strategic Area (KSPK), West Sumatra Province, Indonesia. However, this program has been hampered by a lack of suitable facilities and infrastructure, tourism resources and funds, and a low level of promotion and investment. Therefore, this study aims to identify and analyze the implementation of the Gandoriah-Sunur Beach tourism destination development program as a Pariaman City Tourism Strategic Area (KSPK) in West Sumatra Province. The descriptive qualitative approach using the inductive method was employed, and the data collection was conducted through interviews, observation, and documentation techniques. Furthermore, purposive and snowball sampling approaches were used to identify the informants. Data collection techniques include condensation, presentation, and drawing conclusions. The results show that implementing the Gandoriah-Sunur Beach tourism destination development program as a Pariaman City Tourism Strategic Area (KSPK), West Sumatra Province, is not ideal, as evidenced by the non-linearity of standards with costs and the inefficient allocation of funds.
Rumours as Anticipatory Knowledge in a Future Petro-State
Authors: Witte Annika
Published: January 2022

Building on ethnographic research in Uganda, this paper discusses the mundane practice of rumour mongering and gossiping as anticipatory practices. Crude oil discovery in Uganda brought a small oil boom to the region endowed with the natural resource including some infrastructure development and the presence of foreign oil exploration and construction companies. With these companies came (young) men working for them or aspiring to get employed. However, as the development of the oil remained in a phase not-yet-ness, a temporal space opened for rumours about the oil and anyone involved with it to flourish in the oil region. Especially, since information on the (national) development of the oil project was scarce. The rumours used familiar tropes such as gender stereotypes or witchcraft to relate to the presence of foreign or at least non-local casual workers. Ugandans living in the oil region wondered what negative repercussions the boom might have for them and viewed the strangers with suspicion. During my fieldwork, I encountered rumours of wife-snatching, sexual harassment and even human sacrifice. This paper argues that these rumours can be understood as risks narratives or the sharing of anticipatory knowledge. The rumours were not only reflections of the past but were told in anticipation of the dark side of the future.
Participación de niños, niñas y adolescentes en las escuelas de formación deportiva
Authors: Parra Klusmann Lina Marcela
Published: January 2022

La participación, hace parte de los derechos de los niños, niñas y adolescentes y constituye uno de los cuatro principios fundamentales de la convención sobre los derechos del niño. Beneficiar la participación, es una importante expresión del reconocimiento de la población como sujeto de derecho, alentando que se conviertan así, en agentes activos y presentes en una sociedad. Las escuelas de formación deportiva por su parte, son una estrategia extraescolar que busca favorecer la formación integral del individuo y el sano aprovechamiento del tiempo libre a través del deporte; los niños, niñas y adolescentes que asisten y pertenecen a las escuelas de formación deportiva, disfrutan y aprenden en ellas no solamente a ejecutar correctamente un gesto técnico sino que al contar la mayor parte del tiempo con su motivación, se convierten en un espacio propicio para el desarrollo de contenidos educativos, pedagógicos y sociales; sin embargo de forma sinuosa se generan situaciones de invisibilización de los intereses de la población a beneficiar y se termina disipando un espacio propicio para estimular el crecimiento de sujetos dinámicos y con proyectos de vida que les permitan ser parte activa de una comunidad. Son varios los beneficios de impacto social y de formación general que durante bastante tiempo se le han conferido al deporte, cada cuatro años cuando se disputan los juegos olímpicos, los medios de comunicación enaltecen las grandes historias de esfuerzo y superación de los deportistas, pero fuera de las situaciones mediáticas en nuestro contexto se dificulta proyectar al deporte en otros espacios de reconocimiento y de impacto, como el espacio educativo pilar fundamental en la construcción social y de ciudadanía, por tanto, resulto importante hacer un análisis de la presencia del derecho a la participación de los niños, niñas y adolescentes que asisten a las escuelas de formación deportiva de un municipio, para identificar acciones que permitan la tipificación de este derecho, como relevante en la formación y proyección social.
Trabajadores informales, riesgo ergonómico en trabajadores informales de la zona céntrica de la ciudad de Cali, Valle.
Authors: Hernández Murcia Paula Milena , De La Cruz Rosas. Viviana , Campo Arquimedes Gurrute , Castillo Juan Carlos
Published: January 2022

El empleo informal es toda actividad laboral, que se caracteriza por una alta mano de obra, largas jornadas laborales y baja remuneración salarial, no cuenta con protección social ni beneficios laborales para los trabajadores, los ingresos monetarios están al margen del control y la fiscalización, conectándose así la vulnerabilidad social y laboral, se encuentran expuestos a todo tipo de riesgos, entre ellos, los ergonómicos, por las condiciones del entorno físico; el objetivo de esta investigación fue determinar el riesgo ergonómico al que están expuestos los trabajadores informales, del centro de la Ciudad de Cali, se realizó un estudio cuantitativo, descriptivo, transversal. Participaron 98 hombres y mujeres ocupados en actividades informales del sector comercio, elegidos mediante un muestreo aleatorio simple. Para la recolección de los datos se aplicó la Encuesta Nacional de Condiciones de Salud y Trabajo del Comercio Informal del Ministerio de la Protección Social con previa firma del consentimiento informado. Los resultados mostraron que el 51% de los vendedores informales ejercen posturas o movimientos forzados durante la realización de su actividad laboral. En igual porcentaje levantan y desplazan objetos pesados durante la realización de su actividad laboral, el 77% no cuentan con ayudas mecánicas para desarrollar su actividad; en sus puestos de trabajo existen: pisos, paredes y zonas deterioradas que pueden generar accidentes como resbalones tropiezos y caídas.
Therapeutic Potential of Exosomes Derived From circRNA_0002113 Lacking Mesenchymal Stem Cells in Myocardial Infarction
Authors: Tian Tiantian , Li Feng , Chen Ruihua , Wang Zhiwei , Su Xueming , Yang Chao
Published: January 2022

Exosomes are participated in the pathogenesis of cardiovascular diseases and can be secreted by mesenchymal stem cells (MSCs). However, the effects of circRNA, delivered by exosomes derived from MSCs, on myocardial injury remain unclear. Hence, this study aims to explore the therapeutic potential of exosomes derived from circRNA_0002113 lacking MSCs in the treatment of myocardial injury in vitro and in vivo. Our results reveal that exosomes derived from circRNA_0002113 lacking MSCs decreased cell apoptosis in anoxia-reoxygenation (A/R) model cells, and reduced myocardial injury by inhibiting nuclear translocation of RUNX1 in vitro and in vivo. Moreover, miR-188-3p, which targets RUNX1 in cardiomyocytes was also found to interact with circRNA_0002113. In conclusion, exosomes derived from circRNA_0002113 lacking MSCs could suppress myocardial infarction by sponging miR-188-3p to regulate RUNX1 nuclear translocation. The circRNA_0002113/miR-188-3p/RUNX1 axis mediated alleviation of apoptosis serves as a novel strategy to treat myocardial I/R injury.
Peroxisomal ATP Uptake Is Provided by Two Adenine Nucleotide Transporters and the ABCD Transporters
Authors: van Roermund Carlo W. T. , IJlst Lodewijk , Linka Nicole , Wanders Ronald J. A. , Waterham Hans R.
Published: January 2022

Peroxisomes are essential organelles involved in various metabolic processes, including fatty acid β-oxidation. Their metabolic functions require a controlled exchange of metabolites and co-factors, including ATP, across the peroxisomal membrane. We investigated which proteins are involved in the peroxisomal uptake of ATP in the yeast Saccharomyces cerevisiae. Using wild-type and targeted deletion strains, we measured ATP-dependent peroxisomal octanoate β-oxidation, intra-peroxisomal ATP levels employing peroxisome-targeted ATP-sensing reporter proteins, and ATP uptake in proteoliposomes prepared from purified peroxisomes. We show that intra-peroxisomal ATP levels are maintained by different peroxisomal membrane proteins each with different modes of action: 1) the previously reported Ant1p protein, which catalyzes the exchange of ATP for AMP or ADP, 2) the ABC transporter protein complex Pxa1p/Pxa2p, which mediates both uni-directional acyl-CoA and ATP uptake, and 3) the mitochondrial Aac2p protein, which catalyzes ATP/ADP exchange and has a dual localization in both mitochondria and peroxisomes. Our results provide compelling evidence for a complementary system for the uptake of ATP in peroxisomes.
Viscoelasticity Investigation of Semiconductor NP (CdS and PbS) Controlled Biomimetic Nanoparticle Hydrogels
Authors: Zhao Dan , Zhang Wang , Chen Zhi-Zhou
Published: January 2022

The viscoelastic properties of colloidal nanoparticles (NPs) make opportunities to construct novel compounds in many different fields. The interparticle forces of inorganic particles on colloidal NPs are important for forming a mechanically stable particulate network especially the NP-based soft matter in the self-assembly process. Here, by capping with the same surface ligand L-glutathione (GSH), two semiconductor NP (CdS and PbS) controlled biomimetic nanoparticle hydrogels were obtained, namely, CdS@GSH and PbS@GSH. The dependence of viscoelasticity of colloidal suspensions on NP sizes, concentrations, and pH value has been investigated. The results show that viscoelastic properties of CdS@GSH are stronger than those of PbS@GSH because of stronger surface bonding ability of inorganic particles and GSH. The hydrogels formed by the smaller NPs demonstrate the higher stiffness due to the drastic change of GSH configurations. Unlike the CdS@GSH hydrogel system, the changes of NP concentrations and pH value had great influence on the PbS@GSH hydrogel system. The higher the proportion of water in the small particle size PbS@GSH hydrogel system, the greater the mechanical properties. The stronger the alkalinity in the large particle size PbS@GSH hydrogel system, the greater the hardness and storage modulus. Solution˗state nuclear magnetic resonance (NMR) indicated that the ligand GSH forms surface layers with different thickness varying from different coordination modes which are induced by different semiconductor NPs. Moreover, increasing the pH value of the PbS@GSH hydrogel system will dissociate the surface GSH molecules to form Pb2+ and GSH complexes which could enhance the viscoelastic properties.
The Qingchangligan Formula Alleviates Acute Liver Failure by Regulating Galactose Metabolism and Gut Microbiota
Authors: Yin Ruiying , Liu Shuhui , Jiang Xuejiao , Zhang Xiangying , Wei Feili , Hu Jianhua
Published: January 2022

The Qingchangligan formula (QCLGF) is a traditional Chinese medicine that has significant clinical potential for patients with acute liver failure (ALF). However, the experimental evidence of the effect of QCLGF on ALF and the associated mechanisms remain elusive. We aimed to evaluate the function of QCLGF in ALF and the underlying mechanism. ALF was induced in rats by intraperitoneal injection of D-GalN (1100 mg/kg). The Qingchangligan formula was administered to the rats (6.725 g/kg · d) for 5 days, and the model group and the control group were given the same amount of physiological saline. Then 16S rRNA gene sequencing, high performance gas chromatography-mass spectrometry (GC-MS), and RNA-seq analysis were performed on the samples. The levels of ALT and AST in the ALF rats were abnormal (5322.08 ± 566.27 U/L and 7655.95 ± 1238.08 U/L, respectively) compared with the normal control (98.98 ± 6.90 U/L and 99.63 ± 10.94 U/L, respectively). The levels of ALT and AST in the QCLGF rats (2997.67 ± 469.24 U/L and 4158.40 ± 596.07 U/L, respectively) were closer the normal control group. Liver HE staining showed that the degree of liver damage in the QCLGF rats was lighter than that in the ALF rats. The overall structure of the gut microbiota after ALF was significantly altered, including Proteobacteria, Blautia, Romboutsia, Parabacteroides, UCG-008, Parasutterella, Ruminococcus, norank_f:Lachnospiraceae, the Eubacterium_xylanophilum_group, Oscillibacter, and Eisenbergiella. QCLGF balanced the structure and abundance of intestinal flora. The levels of D(+)galactose, isopropyl beta-D-1-thiogalactopyranoside and D-mannitol were lighter in the plasma of the ALF rats than in the normal control rats, but there were significantly elevated levels of those metabolites in the QCLGF rats. The gene expression changed significantly in the ALF rats. QCLGF regulated the expression of THBS1 and the KEGG pathways of carbohydrate metabolism, lipid metabolism, signal transduction, the immune system, and infectious disease: bacterial. QCLGF may alleviating intestinal flora disorder, regulating galactose metabolism and downregulating the expression of THBS1 to alleviate D-GalN induced acute liver failure.
Sources of CO2 Produced in Freshly Thawed Pleistocene-Age Yedoma Permafrost
Authors: Melchert Jan Olaf , Wischhöfer Philipp , Knoblauch Christian , Eckhardt Tim , Liebner Susanne , Rethemeyer Janet
Published: January 2022

The release of greenhouse gases from the large organic carbon stock in permafrost deposits in the circumarctic regions may accelerate global warming upon thaw. The extent of this positive climate feedback is thought to be largely controlled by the microbial degradability of the organic matter preserved in these sediments. In addition, weathering and oxidation processes may release inorganic carbon preserved in permafrost sediments as CO2, which is generally not accounted for. We used 13C and 14C analysis and isotopic mass balances to differentiate and quantify organic and inorganic carbon released as CO2 in the field from an active retrogressive thaw slump of Pleistocene-age Yedoma and during a 1.5-years incubation experiment. The results reveal that the dominant source of the CO2 released from freshly thawed Yedoma exposed as thaw mound is Pleistocene-age organic matter (48–80%) and to a lesser extent modern organic substrate (3–34%). A significant portion of the CO2 originated from inorganic carbon in the Yedoma (17–26%). The mixing of young, active layer material with Yedoma at a site on the slump floor led to the preferential mineralization of this young organic carbon source. Admixtures of younger organic substrates in the Yedoma thaw mound were small and thus rapidly consumed as shown by lower contributions to the CO2 produced during few weeks of aerobic incubation at 4°C corresponding to approximately one thaw season. Future CO2 fluxes from the freshly thawed Yedoma will contain higher proportions of ancient inorganic (22%) and organic carbon (61–78%) as suggested by the results at the end, after 1.5 years of incubation. The increasing contribution of inorganic carbon during the incubation is favored by the accumulation of organic acids from microbial organic matter degradation resulting in lower pH values and, in consequence, in inorganic carbon dissolution. Because part of the inorganic carbon pool is assumed to be of pedogenic origin, these emissions would ultimately not alter carbon budgets. The results of this study highlight the preferential degradation of younger organic substrates in freshly thawed Yedoma, if available, and a substantial release of CO2 from inorganic sources.
The Association Between the Decline of eGFR and a Reduction of Hemoglobin A1c in Type 2 Diabetic Patients
Authors: An Lingwang , Yu Qiuzhi , Chen Linhui , Tang Hong , Liu Yanjun , Yuan Qun , Ji Yu , Lee Yaujiunn , Lu Juming
Published: January 2022

Objective

This study aimed to explore the relationship between short-term (≤12 months) changes in the estimated glomerular filtration rate (eGFR) and hemoglobin A1c (HbA1c) in patients with type 2 diabetes (T2D).

Method

A total of 2,599 patients with T2D were enrolled if they were registered in the Diabetes Sharecare Information System, were aged 18–75 years, and had 2–3 HbA1c and eGFR measurements within the preceding 12 months. The studied patients were categorized into five groups based on eGFR, i.e., the relatively stable (RS), fast decline (FD), modest decline (MD), modest increase (MI), and fast increase (FI) groups.

Results

The median eGFR changes from baseline were −22.14, −6.44, 0.00, 6.32, and 20.00 ml/min per 1.73 m2 for patients in the FD, MD, RS, MI, and FI groups, respectively. Up to 1,153 (44.4%) subjects experienced an eGFR decline of ≥3.5 ml/min per 1.73 m2, including 821 (31.6%) FD subjects and 332 (12.8%) MD subjects. A decreased trend was found between the eGFR change and HbA1c decrease category, even after multivariable adjustment. In general, an eGFR FD was frequently found in patients who had an HbA1c reduction of ≥3.00% and a baseline HbA1c ≥8.0%; alternatively, such a result was also observed for a urinary albumin-to-creatinine ratio (UACR) of 30.0–300.0 mg/g, regardless of a diabetes duration of <10.0 or ≥10.0 years, or in patients who had an HbA1c reduction of ≥1.00% accompanied by hyperfiltration.

Conclusions

Some patients with T2D experienced an eGFR FD or MD during the ≤12-month follow-up period. A significant downward trend in eGFR change was demonstrated alongside an HbA1c reduction, independent of UACR stage, diabetes duration, and hyperfiltration. Sustained monitoring and cautious interpretation of the HbA1c and eGFR changes will be needed in clinical practice.
Efficacy and Safety of Lactobacillus plantarum K50 on Lipids in Koreans With Obesity: A Randomized, Double-Blind Controlled Clinical Trial
Authors: Sohn Minji , Na Ga Yoon , Chu Jaeryang , Joung Hyunchae , Kim Byung-Kook , Lim Soo
Published: January 2022

Background

Only few studies have investigated the role of probiotics in the development of obesity. We aimed to determine the efficacy and safety of an intake of Lactobacillus plantarum K50 (LPK) on body fat and lipid profiles in people with obesity.

Methods

This randomized, double-blind, placebo-controlled, clinical trial involved 81 adults with a body mass index of 25–30 kg/m2 who were assigned randomly to a diet including 4 × 109 colony-forming unit of LPK or a placebo. Changes in body fat, anthropometric parameters, and biomarkers of obesity were compared using a linear mixed-effect model.

Results

After 12 weeks of treatment, body weight, fat mass, and abdominal fat area did not change significantly in the two groups. However, total cholesterol levels decreased from 209.4 ± 34.4 mg/dL to 203.5 ± 30.9 mg/dL in the LPK group, but increased from 194.7 ± 37.5 mg/dL to 199.9 ± 30.7 mg/dL in the placebo group (P = 0.037). Similarly, triglyceride levels decreased from 135.4 ± 115.8 mg/dL to 114.5 ± 65.9 mg/dL in the LPK group, with a significant difference between groups. LPK supplementation also tended to decrease leptin levels compared with placebo. It also changed the distribution of gut microbiota significantly, with an increase in L. plantarum and a decrease in Actinobacteria, both of whose changes in abundance were correlated with changes in visceral adiposity, with borderline significance.

Conclusion

A 12-week consumption of LPK reduced the total cholesterol and triglyceride levels significantly with favorable alterations in microbiota, suggesting potential benefits for controlling blood lipid profiles.