bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of the frequency of BRCA1/2 mutations detection by means of PCR in State
Budgetary Healthcare Institution «Saint-Petersburg clinical scientific and practical
center for specialised types of medical care (oncological) named after N.P.
Napalkov»
Authors: Abduloeva N.K. , Moiseenko V.M. , Nikulushkin N.G. , Kazakova1 K.N. , Kaitova S.K. , Yegorenkov V.V. , Volkov N.M. , Shelekhova K.V. , Skripko O.A. , Scriabin M.V. , Moiseenko F.V. , Zhabina A.S.
Published: November 2023

Background.BRCA1/2 germline testing allows us to optimize treatment strategy for
patients with breast and ovarian cancer cases,to provide early diagnosis and also
prophylactic measures for mutation carriers. Considering absence of large BRCA studies
on Russian population, we do not have any clear understanding of approximate BRCA1/2
germline mutation frequency, a whole number of founder mutations and impact of
non-founder BRCA1/2 mutations, which are not included in a standard PCR panel.
Objective. Assessment of the frequency of BRCA1/2 mutations detection by means of PCR in
breast and ovarian cancer patients in real clinical practice in St. Petersburg Clinical
Scientific and Practical Center for Specialized Types of Medical Care (oncological)
named after N.P. Napalkov. Analysis of a database for BRCA1/2-negative patients on a
presence of risk factors associated with a probability of carrying a germline mutation
in BRCA1/2 genes. Materials and methods. We retrospectively evaluated 335 ovarian and
1196 breast cancer patients, tested for germline BRCA1/2 by PCR in SPb CSPC(o) named
after N.P. Napalkov from 01.01.2019 to 31.12.2021. For analysis was used patient’s blood
plasma and a standard PCR panel detecting 8 mutation variants. A database for
BRCA1/2-negative patients was retrospectively analyzed on a presence of risk factors
associated with a high probability of hereditary cancer: an early onset and family
history of cancer (BRCA associated). Statistical analysis was carried out using the SPSS
software package (IBM® SPPS® Statistics v. 20), a number of graphs were carried out
using Microsoft® Excel® 2016 programs. Results. BRCA1/2 germline mutations were detected
in 6,4% (n= 98). Mean frequency of detection was 12,6% (n=45) for ovarian cancer
patients, 4,3% (n=53) for breast cancer patients. Analysis of a database for
BRCA1/2-negative patients demonstrated that 22,5% (n=346) BC and OC cases had an early
onset. Family history of cancer was identified for 13,6% (n=195) patients with breast or
ovarian cancer, including 3,8% (n=43) with 2 and more family cases of BRCA associated
cancers. Conclusions. The frequency of detected BRCA1/2 germline mutations by PCR for
breast and ovarian cancer patients in SPb CSPC(o) named after N.P. Napalkov is lower
than the one described in international data. A large part of patients BRCA1/2 negative
by PCR test has characteristics of hereditary breast cancer syndrome and requires
further NGS.
propriedade privada e a Maioria: Rastreando um conflito doutrinário nos precursores do pensamento liberal
Authors: Borba Pedro
Published: November 2023

O trabalho se propõe a investigar a tensão entre propriedade privada e vontade da maioria, entendido como um problema normativo essencial ao liberalismo. Transporta, então, a discussão para um contexto histórico anterior ao liberalismo enquanto tal, analisando autores que essa tradição viria a reivindicar como seus antecessores. O artigo constrói uma linha que percorre a obra de John Locke, de Montesquieu e dos Federalistas estadunidenses. De um lado, sinaliza a formação conceitual dos termos da questão: uma propriedade privada individual, exclusiva e ilimitada como direito cidadão e a prevalência da soberania popular como governo da maioria, cujo conflito doutrinário atinge clareza histórica no debate constitucional dos Estados Unidos. O encaminhamento liberal da questão a partir do século XIX, que atribui a prevalência do direito de propriedade sobre a vontade majoritária, operaria sobre uma síntese entre a teoria lockeana da propriedade, o princípio da moderação de Montesquieu e a arquitetura constitucional madsoniana. Não obstante seus anacronismos, essa apropriação forneceria o arcabouço para a conciliação entre indivíduo e sociedade no liberalismo político.
O impeachment no Estado democrático de direito brasileiro
Authors: Goveia Rechia Douglas
Published: November 2023

Diante do processo que levou ao impeachment da Presidente Dilma Rousseff em 2016, foram suscitados debates acerca da natureza do juízo realizado pelo Senado Federal brasileiro nos crimes de responsabilidade, ficando nítida a necessidade de uma delimitação teórica acerca da espécie de julgamento levado a cabo, seja ele político, jurídico ou misto. Neste trabalho, pretende-se realizar, por meio da fenomenologia hermenêutica, uma análise crítica do processo histórico pelo qual o impeachment foi incorporado no país, bem como explorar as correntes que apontam a natureza do instituto no Brasil. Finalmente, tendo em vista o contexto político-institucional específico do Brasil, o presente artigo realiza um debate teórico a respeito do impeachment para que se encontre uma solução satisfatória aos parâmetros do Estado Democrático de Direito instituído pela Constituição Federal de 1988.
Origem Institucional e dependência de trajetória
Authors: Tokumoto Alessandro
Published: November 2023

O artigo tem como objeto a origem institucional de dois bancos de desenvolvimento, o Banco Nacional de Desenvolvimento Econômico e Social (BNDES) e do Banco de Crédito Industrial Argentino (BCIA). Utiliza-se o método histórico comparativo para identificar quais fatores institucionais e contextuais na criação dessas instituições são relevantes para compreender a dependência de trajetória do BNDES, no caso brasileiro, e o caso do BCIA, na Argentina. Os resultados indicam que variáveis políticas-históricas refletiram no desenho institucional adotado em cada nação. No caso brasileiro, a forte burocracia estabelecida possui relação com as raízes técnicas do BNDES e com a orientação ideacional dos governantes da época. No caso argentino, a debilidade institucional do BCIA foi historicamente condicionada pelo processo político de criação dessa agência e pelo baixo grau de autonomia estabelecido ao longo de sua existência.
Mulheres partidárias
Authors: Teixeira de Barros Antonio , Da Silva Nascimento Willber
Published: November 2023

O artigo analisa como as mulheres filiadas a partidos políticos atuam no âmbito interno da estrutura e da organização das legendas. O foco analítico está na participação das mulheres nas atividades partidárias, considerando que a literatura aponta tal participação como um dos fatores que impulsionam carreiras políticas femininas. São avaliadas como os seguintes fatores influenciam essa participação: variáveis socioeconômicas; capital familiar e capital militante; espectro ideológico das legendas; interesse das informantes em se candidatar para disputar eleições. A hipótese, confirmada, é que mulheres filiadas a partidos de esquerda, solteiras e mais escolarizadas são as mais participativas na estrutura das agremiações. O estudo deriva de um questionário com 419 filiadas. O principal locus de atuação delas se dá na esfera virtual. Os movimentos estudantis e sociais são os principais mecanismos de recrutamento partidário de mulheres de esquerda, enquanto na direita são as relações de parentesco.
El Problema del Pesebre en La Moneda
Authors: Bellolio Cristóbal
Published: November 2023

Uno de los renovados focos de interés de la teoría política liberal ha sido la forma en que los estados despliegan símbolos religiosos en el uso de su capacidad expresiva, es decir, sin coerción. ¿Son estas formas de establecimiento religioso simbólico permisibles en un estado formalmente separado de la iglesia? Esta pregunta es pertinente para el caso chileno, donde la autoridad conmemora una serie de ritos religiosos al interior del palacio de gobierno, siendo la instalación de un pesebre gigante de Navidad el que genera más resistencia en una fracción de la creciente población de ateos, agnósticos y no creyentes en general. Este artículo recurre a la recientemente influyente teoría del “secularismo mínimo” de Cecile Laborde para concluir que el pesebre en La Moneda solo es políticamente relevante si envía un mensaje de exclusión cívica a una identidad vulnerable y subordinada, lo que es difícil de argumentar desde la perspectiva de sus críticos.
Forças Armadas e Segurança Pública no Brasil
Authors: Diniz Rocha Pedro
Published: November 2023

O objetivo deste artigo é o de identificar o perfil das Operações de Garantia da Lei e da Ordem (GLOs) empregadas no Brasil entre 1992 e 2020. Para tanto, foram analisados dados compilados pelo Ministério da Defesa (MD) por meio de técnicas de estatística descritiva. Da análise se desprende que a frequência das operações foi constante durante todo o período, que operações ligadas à segurança de eventos são as mais comuns, e que àquelas relativas à violência urbana duram em média cinco vezes mais do que todas as outras. Foram também descobertas diferenças nos tipos de operações empregadas em cada região e estado do Brasil. Por fim, em termos de frequência de GLOs, o Sul parece ser uma exceção, tendo sido palco de cerca de seis vezes menos operações quando comparado as outras regiões. Para o futuro, uma análise comparativa deste fenômeno pode indicar as causas estruturais que impulsionam o seu emprego no resto do Brasil, mas não nos estados do Sul.
Democracia y Violencia Política en Colombia
Authors: Palacios Nohra , Sánchez Lopéz de Mesa Alejandro , Tovar Joaquín , Llanos Cristian
Published: November 2023

Este articulo tiene por objetivo estudiar la violencia política en siete departamentos en Colombia, entre 1984 y 2019, para comprender su relación con los ciclos de apertura y cierre democrático del país. Para realizar esta investigación se construyó una matriz de datos que permite leer cualitativamente los cambios en la intensidad de la violencia política. Las tres partes que componen este artículo proponen una manera de explicar la convivencia de democracia y altos niveles de violencia política, a partir de la combinación de un relato del nivel nacional y ejercicios de caracterización de distinto tipo en los niveles subnacionales. Uno de los hallazgos del artículo es que las diferentes temporalidades de la violencia, así como las formas disímiles del conflicto transforman las condiciones de la competencia electoral a nivel subnacional. Las formas en que se compite por el control territorial (particularmente la presencia de uno o más actores con pretensiones de dominación) resultan determinantes para explicar la violencia política y comprender cómo el conflicto incide en la configuración de los sistemas de partidos en el nivel departamental.
Presenças femininas nas Câmaras Municipais do ABC Paulista e seus efeitos nas políticas públicas locais
Authors: Stuchi Carolina , Paula Silva Alves Gabriela
Published: November 2023

Embora a discussão acerca do acesso das mulheres ao poder tenha se ampliado, ainda falta, à literatura sobre os efeitos nas políticas públicas quando essa representação ocorre. Visando contribuir com o debate, a hipótese aqui colocada é de que o comportamento legislativo feminino se diferencia dos homens e, em consequência disto, tem efeitos sobre a produção legislativa no poder local. O artigo parte da bibliografia sobre a presença feminina no legislativo e da coleta de informações sobre as vereadoras dos sete municípios do ABC paulista, no período de 2005 até o primeiro semestre de 2019, com análise de seus perfis e leis aprovadas, além de três entrevistas com vereadoras da atual legislatura, procurando compreender como a presença de mulheres no legislativo influencia a produção de políticas públicas. Os achados confirmam o baixo percentual de mulheres e a tendência de prioridades legislativas em temas sociais, com maior produção legislativa em temas tradicionais de vereança.
E-participação nos governos Cid Gomes e Camilo Santana (2011-2018)
Authors: Barbalho Alexandre , Moreira Gabrielle D'Annunzio Cavalcanti
Published: November 2023

O artigo avalia a ferramenta de e-participação Banco de Ideias no período do segundo governo Cid Gomes (2011-2014) e do primeiro governo Camilo Santana (2015-2018), ambos no estado do Ceará, procurando compreender sua contribuição na implementação das políticas públicas e como ferramenta de e-participação e seus possíveis ganhos democráticos decorrentes. Realizou-se uma abordagem qualitativa com objetivo exploratório, apoiada em levantamento bibliográfico e documental e em entrevistas semiestruturadas com os atores envolvidos no objeto de análise. Concluiu-se que a ferramenta proporcionou os ganhos democráticos mas perdeu sua efetividade na mudança de governos.
Defesa, desenvolvimento e controvérsias tecnológico-produtivas
Authors: Mohr Corrêa Gilberto , Bichoffe Ana Carolina
Published: November 2023

O ciclo de revitalização da defesa nacional experienciado nos Governos Lula e Dilma, partiu de uma construção sociológica que buscou associar o investimento nos meios de defesa do país ao seu desenvolvimento. Nesse contexto, programas de reequipamentos militares passaram a ser legitimados como importantes programas nacionais. Seguindo a tradição sociológica pragmática, este artigo contribui para o estudo integrado de dimensões sociais, técnicas, políticas econômicas e estratégicas em torno da questão material da defesa nacional e sua associação com o espírito de uma época marcado pelo discurso desenvolvimentista. Nesse âmbito, um caso que se tornou emblemático foi a aquisição dos caças para a Força Aérea Brasileira. Fruto de um complicado processo decisório que se arrastou por praticamente duas décadas, os caças suecos Gripen foram finalmente declarados como vencedores da concorrência Projeto F-X2 e os contratos associados foram assinados em 2014. A trajetória da decisão envolveu incerteza compartilhada e não concordâncias, com agentes engajados e grupos que tomaram posições distintas, caracterizando-a como uma controvérsia segundo a tradição sociológica pragmática. Devido a centralidade que a controvérsia da substituição dos caças assume nas interfaces tecnológico-produtiva e militar-civil, o caso é ideal para mostrar de maneira dinâmica a formação de agência nas redes socio-técnicas. A pesquisa se ancora em levantamento empírico em corpus de artigos jornalísticos publicados em jornais de grande circulação brasileiros, compreendidos como dispositivos da controvérsia. Por meio da cartografia das controvérsias se identificaram os momentos críticos de visibilidade, grupos de atores participantes, e a conformação dos principais temas controversos. O aprofundamento de importantes translações, realizadas ao longo da trajetória, permite mostrar a construção de razões sociológicas em torno da relação entre defesa e desenvolvimento, de material de defesa e da substituição dos caças especificamente. Dentro de um projeto de revitalização da indústria de defesa justificado com base no desenvolvimento nacional, a opção pela aquisição de aeronaves estrangeiras acompanhada de transferência de tecnologia – Projeto F-X2 – se tornou um ponto de passagem obrigatório na medida que foi capaz de traduzir o interesse de uma variedade de atores.
Diálogos em torno do "ultrapresidencialismo" estadual
Authors: Silame Thiago , Silva Denisson
Published: November 2023

O artigo realiza uma revisão sistemática da literatura produzida pela Ciência Política Brasileira sobre a relação executivo-legislativo nas assembleias legislativas estaduais, estabelecendo um diálogo com a obra pioneira “Os Barões da Federação” de Abrucio e o conceito de “ultrapresidencialismo” estadual. Três perguntas principais orientam o trabalho:1) como a literatura discute a construção de apoio aos governadores?; 2) o governismo é o padrão de relacionamento entre os poderes? e; 3) quais são os microfundamentos do comportamento parlamentar? A importância do trabalho pioneiro de Abrucio foi confirmada uma vez que cerca de 82% dos trabalhos o mobilizam. Contudo, os trabalhos estabelecem um diálogo crítico em relação ao predomínio do ultrapresidencialismo. Padrões diversos ao governismo são observados nos estudos das assembleias. Assim sendo, três padrões podem ser observados: o governismo, assembleias autônomas e assembleias politizadas.
A contribuição de Bresser- Pereira para a (re)construção intelectual do Estado brasileiro
Authors: Ramos de Miranda Daniel Estevão
Published: November 2023

Luiz Carlos Bresser-Pereira é um dos intelectuais brasileiros com a produção mais extensa e influente no campo de estudos sobre administração pública e burocracia. Neste trabalho, analisa-se sua atuação como ator e autor na reforma gerencial dos anos 1990 em diante. A partir de uma análise documental de seus escritos, discute-se como sua estratégia enquanto ator político reformador articulou-se com sua atuação enquanto autor. A principal conclusão é que a duplicidade ator-autor não foi contingente, mas sim estruturante da própria reforma gerencial e de seu legado.
A consolidação do Fórum Brasileiro de Pós-Graduação em Ciência Política
Authors: Magalhães Bruno Dias , Ribeiro Lucas Henrique , Marques Carla Beatriz Raulino , Costa Maycon Yuri Nascimento , Oliveira Marina Souto Rodrigues de
Published: November 2023

Em 2009, mais precisamente entre os dias 21 e 23 de outubro, ocorria na Universidade Federal de Minas Gerais o I Fórum Brasileiro de Pós-Graduação em Ciência Política (FBCP). A iniciativa, concebida e executada por estudantes, daria início não só à principal arena de discussão, intercâmbio e produção de conhecimento entre os pós-graduandos da disciplina, mas tornar-se-ia ao longo dos anos um espaço fundamental de articulação crítica e, por isso mesmo, de formação de lideranças do campo. Naquele então, o evento debruçou-se sobre os desafios metodológicos da Ciência Política, inaugurando também o que seria outro aspecto marcante dos encontros: a presença de pensadoras e pensadores de referência, tanto no âmbito nacional, quanto internacional. Assim, a palestra principal coube a Adam Przeworski, cujo trabalho e influência dispensa apresentações.
Tres politólogas y el #8M
Authors: Duarte Lima de Barros Ana Tereza
Published: November 2023

En el marco de conmemoración del 8 de marzo de 2022, día de lucha global por y desde las mujeres trabajadoras, la politóloga Ana Tereza Duarte invitó a tres de las coordinadoras de la Red de Politólogas, quienes concedieron, por separado, entrevistas exclusivas en diálogo con sus campos actuales de trabajo, incidencia e investigación. La idea principal fue conectar sus perspectivas con la agenda de los feminismos en la actualidad y encontrar sinergias entre academia, sociedad civil y disputa ciudadana por espacios de poder.
Apomorphine Sublingual Film Compared with Subcutaneous Apomorphine for OFF Episodes in Parkinson’s Disease: An Open-Label, Randomized, Crossover Study
Authors: Stocchi Fabrizio , Rascol Olivier , Poewe Werner , Chaudhuri K. Ray , Kassubek Jan , Lopez Manzanares Lydia , Zhang Yi , Bowling Alyssa , Pappert Eric , Wu Stacy ,   for the CTH-302 Study Investigators
Published: November 2023

Background:

Apomorphine sublingual film (SL-APO) and subcutaneous apomorphine (SC-APO) have been used for the treatment of OFF episodes in Parkinson’s disease (PD). No study has prospectively compared efficacy and safety of these formulations.

Objective:

To compare SL-APO with SC-APO for treatment of OFF episodes in PD.

Methods:

An open-label, randomized, crossover study assessed SL-APO versus SC-APO in patients with PD and OFF episodes ( N = 113). Doses were optimized in randomly assigned order. SL-APO dose initiation (10 mg) occurred in clinic; further dose optimization (15–30 mg; 5-mg increments) occurred primarily at home. SC-APO dosing (2–6 mg; 1-mg increments) occurred entirely in clinic. After a 3–7-day washout, patients were randomized 1 : 1 to 4 weeks of treatment with their optimized dose of SL-APO or SC-APO, followed by washout and 4 weeks of crossover treatment.

Results:

Propensity score matching applied on 159 patients (STN-DBS n = 75, MED n = 84) resulted in 40 patients in each treatment group. At 36-month follow-up, STN-DBS led to significantly better PDSS and PDQ-8 change scores, which were significantly correlated. We observed no significant effects for HADS and no significant correlations between change scores in PDSS, HADS, and LEDD.

Conclusions:

We report Class IIb evidence of beneficial effects of STN-DBS on quality of sleep at 36-month follow-up, which were associated with QoL improvement independent of depression and dopaminergic medication. Our study highlights the importance of sleep for assessments of DBS outcomes.

Results:

No difference was observed between SL-APO and SC-APO for change from predose to 90 minutes postdose in Movement Disorder Society Unified Parkinson’s Disease Rating Scale Part III score at week 4 (primary endpoint), assessed by a blinded rater (–13.6 vs. –13.8, respectively; p = NS). Overall, 72.2% of patients preferred SL-APO compared with SC-APO/no preference ( p = 0.0002) per the Treatment Preference Questionnaire (secondary endpoint). Patients reported greater satisfaction with SL-APO compared with SC-APO, per mean scores of convenience (73.7 vs. 53.5) and global satisfaction (63.9 vs. 57.6) on the Treatment Satisfaction Questionnaire for Medication (other endpoint). The safety profiles of both treatments were generally comparable and were well-tolerated.

Conclusions:

Patients reported overall preference for and greater satisfaction with SL-APO over SC-APO.
The Etiology of Parkinson’s Disease: New Perspectives from Gene-Environment Interactions
Authors: Bogers Jolien S. , Bloem Bastiaan R. , Den Heijer Jonas M.
Published: November 2023

Parkinson’s disease is now the most rapidly growing neurodegenerative disease worldwide. It is therefore critical to identify which factors, and to what extent, contribute to the multifactorial etiology of Parkinson’s disease. Here, we address two interesting elements from the perspective of genetics, namely (a) the estimated age of several genetic risk factors related to Parkinson’s disease; and (b) the relative contribution of genetics to the etiology of Parkinson’s disease, as derived from twin studies. Based on these two perspectives, we argue that most genetic risk factors are by themselves insufficient to explain the majority of Parkinson’s disease, and that environmental factors are required for these genetic factors to become pathophysiologically relevant.
Analysis of the compliance of windows with up to day energy efficiency requirements
Authors: Klimova I. , Moiseienko V.
Published: November 2023

Due to the consequences of the energy and environmental crises, reducing energy consumption in buildings is an urgent task, both globally and nationally. It is this goal that causes a constant increase in the requirements for resistance to heat transfer of the external enclosing structures of buildings in climatic conditions, where the design temperature of the outside air is at the level of -20ºС. Increasing the resistance of non-transparent enclosing structures is achieved by available means that allow guaranteed achievement of the designated resistance to heat transfer. Increasing the heat transfer resistance of transparent (or translucent) enclosing structures has limitations that limit the maximum values. The analysis of window designs that are offered on the construction market of Ukraine in the context of the requirements of DBN V.2.6.31-2021 "Thermal insulation and energy efficiency of buildings" was carried out. To increase the resistance to heat transfer of windows, the manufacturer has (today) three constructive means - an increase in the number of chambers, the use of selective coatings and filling the chambers with an inert gas argon. It should also be taken into account that the production of windows is a multicriteria task, in which the achievement of a certain level of resistance to heat transfer is one of the factors among others, no less important. The results of the analysis show that the fulfillment of the requirement Rqmin≥0.9 m2•ºС/W for the first temperature zone of Ukraine requires the use of all technical means available from manufacturers. A sample of eighty-two window designs that are actually offered on the Ukrainian construction market was analyzed. Compliance with the requirements for the second temperature zone was achieved for forty-three percent of window designs. Compliance with the requirements for the first temperature zone was achieved for seventeen percent of window designs. The complexity and increased cost of such structures may necessitate additional control measures at the completion of construction and during the operation of buildings.
The selection of a methodology for calculating the heat load of hot water supply systems for facilities with significant uneven consumption
Authors: Glamazdin P. , Chepurna N. , Koziachyna B.
Published: November 2023

When determining the amount of thermal energy required for the functioning of the hot water supply system for any building, the question of choosing a heating method arises. It is especially relevant to accurately predict the capacity of the hot water supply system for facilities with pronounced uneven hot water consumption. In this research, a comparative analysis of methods for determining the maximum design flow rate of hot water was performed, which plays an important role in the selection of equipment for heating water in the flow mode. On the example of the main building of KNUCA, the problem of determining the total design hot water flow rate for buildings characterized by an uneven mode of water consumption is revealed. Monitoring of the actual mode of water consumption of the main building of KNUCA was carried out, as a result of which the real total hot water flow rate during the working day of the university was determined.
Design of displacement ventilation system in museum premises
Authors: Vakhula V.
Published: November 2023

In museum premises located in architectural monuments, an important issue is ensuring the regulatory parameters of the air environment. And the method of organizing air exchange in exhibition and exposition halls. In such buildings, it is impossible to conduct air ducts, therefore existing ducts from fireplaces and natural exhaust ducts are used. The article discussed the National Center of Folk Culture "Ivan Honchar Museum". In a series of field studies, the average air temperature in the room was within twz = 20 °С, and the relative humidity was φwz = 55-60 % in the exhibition halls. two options for organizing air exchange. A three-dimensional model was created for the study of air exchange and air flow between halls, and air movement was simulated in two variants for rooms No. 40, 47 and 48. Taking into account the field studies and mathematical modeling of air exchange organization options, a project for the modernization of ventilation and air conditioning systems was proposed.
Thermal modernization and improvement of ingeneering systems of campus F of National University "Yuri Kondratyuk Poltava Polytechnic"
Authors: Guzyk Dmitriy , Cherednikova Oleksandra , Dubchak Dmytro , Nesterenko Bohdan , Perederii Alina , Simon Oleksiy
Published: November 2023

In the article, the relevance of the topic, namely the determination of an effective way to increase the shelf life of food products, was revealed. The latest studies and publications devoted to the theoretical and practical aspects of dry food production technology were analyzed. The most important requirements for drying systems and the main methods of drying fruit raw materials were considered and the goals of the work were formulated. The design of a chamber convection dryer for testing in the laboratory of the Department of Heat and gas supply, ventilation, and thermal power engineering of the National University "Yuri Kondratyuk Poltava Polytechnic" was presented. The obtained results of banana drying, their analysis, and comparison with the selection of the optimal option for the drying mode were given. Conclusions from the performed work were presented.
Development of energy supply civil engineering system in Ukraine
Authors: Devterov Illja , Zinych Petro
Published: November 2023

The current state of energy supply of civil engineering systems in Ukraine and resources that can be developed and used to increase energy efficiency and energy independence are investigated in the work based on a systemic approach, analysis and synthesis of important questions on the research topic, as well as the method of observation, measurement, formalization and generalization countries in the conditions of the globalization of the world economy, as well as the integration of artificial intelligence systems and neural networks in all spheres of life. The relevance of the research lies in Ukraine's desire for energy independence and energy efficiency of existing systems, modernization of energy supply systems, which are already outdated and have low efficiency and efficiency. Further ways of improving and optimizing the energy supply of civil engineering systems in Ukraine are being researched, and their feasibility is proven. It is concluded that understanding the importance of these issues will lead to energy independence and energy security of the country as a whole, as well as an increase in the volume of civil construction and energy renovation of civil buildings. Special attention is paid to RES, which are already used in Ukraine, are quite energy-efficient and preserve the environment, which increases the country's competitiveness in the world energy supply market, as well as the production of many goods and services that are relevant today. Leading experts in the field of civil engineering and energy consider the development of renewable energy sources (RES) as one of the most important ways to energy independence of Ukraine and the development of civil engineering systems, the needs of which are growing along with the construction of new consumer facilities. The further development of this work consists in the targeted monitoring of problematic links of the modern energy supply system and the implementation of the latest developments of domestic and foreign specialists, which are already available today and allow to significantly reduce the percentage of energy costs in all areas of energy supply stem of civil engineering.
Analytical studies of the functioning of ventilation with local cooling in public buildings
Authors: Korbut Vadym , Tkachenko Tetiana , Mileikovskyi Viktor , Vakhula Volodymyr , Konovaliuk Viktoriia
Published: November 2023

Today, the creation of optimal microclimatic conditions is mandatory for the vast majority of premises in public buildings. The main problem in the cooling period of the year is the minimization of energy consumption. Traditional systems with recirculation require the return of exhaust air to the ventilation unit, which is obviously accompanied by additional energy costs for its movement. In addition, this enlarges air handling units, airducts and other equipment. This problem is not present in ventilation systems with local cooling. They consist of a ventilation system that provides a minimum flow of outdoor air and local closers that take air from the upper or middle zone, cool it and supply it to the room. The work considers the principles of analytical description of processes in a room with the simultaneous operation of ventilation and local cooling. A calculation algorithm and a software based on it have been created. The basis of the analytical description is the simplification that the supply air and the air after the closers are first mixed, and then the mixture participates in the assimilation of excess heat and moisture in the room. The influence of various factors on the productivity and cold performance of the guides is analyzed. It is shown that for maximum energy efficiency with minimum costs, it is necessary to perform the calculation, and not to use aggregated indicators. It is shown that the performance of the closers can exceed the consumption of outside air. The closers return the exhausted air to the working area, which leads to an increase in the carbon dioxide content in it and the possibility of the return of pathogenic microorganisms and viruses to it. It is shown how both problems are solved by a biotechnological measure - remedial phytodesign. The recommended assortment of plants is given.
The Random Somatic Mutation is not Quite Random
Authors: Smarandache Florentin
Published: November 2023

This research note challenges the idea that Random Somatic Mutations are entirely random, highlighting their non-equiprobable nature and their influence on evolution, involution, or indeterminacy. It recalls the Neutrosophic Theory of Evolution, extending Darwin’s theory, and emphasizes the importance of distinguishing between different senses of “random mutation” in evolutionary theory.
Fintech- a solution for financial inclusion and women’s economic empowerment?
Authors: Babar Hasan
Published: November 2023

Financial Inclusion seems to be the light at the end of the tunnel to achieve the Millennium Development Goals (MDGs) which can eradicate poverty and help people to come out of abject poor conditions. Financial Technology (FinTech) is spreading at a fast pace and being accessed by the masses. Thus, this technological innovation which helps to deliver financial services more conveniently and efficiently can hold the key for financial inclusion and women empowerment through financial inclusion. This study used data from the World Bank’s 2017 Global Findex report and tried to find a relation between FinTech and financial inclusion from 144 countries. A few parameters from the report were taken to measure the financial inclusion variable and some indicators were selected to assess the FinTech reach. The results suggested that there is a strong relationship between the independent variable FinTech and the dependent variable financial inclusion for the whole population and women population alone. The study also found that low-income countries are financially excluded while high-income countries are more inclusive except few exceptions. The study will help to understand the impact of FinTech on the inclusion of the excluded population from the financial system and can act as a solution for reducing poverty and women's empowerment.
ALR_Sim_tracks - trajectory simulator software to assist the search for favourable trajectories for the exploration of the triple Asteroid 2001-SN263 from the Laser Altimeter point of view
Authors: Vicente de Brum Antonio Gil
Published: November 2023

_ALR_Sim_tracks_ is a trajectory simulator/analyser software for space missions involving the exploration of the surface of celestial bodies using optical instrumentation. The software was created to carry out an analysis that would allow the identification of favourable trajectories for carrying out the intended exploration of the triple asteroid 2001-SN263 during Brazil's first deep space mission (ASTER mission) [1][2] from the point of view of the Laser Altimeter, called ALR, which is one of the optical instruments designed to fly in this mission [3][4]. With its use, trajectories of interest for the intended exploration were simulated and evaluated to identify the most promising ones, which were then presented [5][6]. This article contains a presentation and description of this software, and everything involved in its operation. Because it was first created to represent the view of a laser altimeter, the descriptions involve this instrument. However, Other optical instruments of similar operation are also considered for analysis once a proper modelling is available.
Media construction of HIV
Authors:   , Hursey Devin
Published: November 2023

Many of the challenges experienced by people living with HIV relate to biases, stigma, and conceptualization of HIV, rather than to the scientific realities of the virus itself or the medical impacts of living with the virus. This study uses the loosely defined theory of Media Construction of Social reality, described by Fengmin Yan as a process involving gatekeeping and framing. The Null Hypothesis is that media sources do not influence dependent variables and do not differ from the those who receive information from friends or family members living with HIV, is not supported. Receiving information from Friends or Family Members living with HIV is negatively correlated with HIV knowledge (r=-.177, p [less than] 0.001) and not significantly correlated with knowledge of HIV (r=-.089, p=0.055). HIV Knowledge and HIV Stigma appear to be statistically unrelated (r=0.027, p=0.576).
A glimpse of the potential of task-based language teaching in fostering effective communication (on the example of the topic Mood Food)
Authors: Ivanova Iryna , Potapenko Liudmyla , Palienko Aliona
Published: November 2023

It is a matter of common fact that the modern world is becoming more and more globalized. The desire of students to become multilingual is clear and justified. Without any doubt, those who are fluent not only in their mother tongue, but also in other languages will, have higher competitiveness in the labour market. Knowledge of a foreign language, especially English, is an urgent need both for professional and personal growth. It is considered an important component of future professional image. All these prerequisites have given rise to launching an elective course “Communicative English” at Cherkasy State Business College. The offered toolkit can serve as a teacher’s set of resources to foster effective communication related to the topic MOOD FOOD. The analysis of top current trends in teaching ESL proves that Task-Based Language Teaching (TBLT) will continue to dominate classrooms. The material is designed in accordance with TBLT approach facilitating students’ engagement in meaningful communication. It presents the combination of TBLT with the other educational approaches such as authenticity, gamification of learning, cultural awareness, creativity, collaboration, inquiry-based learning. The presented tasks and activities enable a teacher to create a learning environment rather than just a classroom inspiring students and having better outcomes.
2620-102X
Authors: Challoumis Constantinos
Published: November 2023

This work is about the utility of the cycle of money with the maximum mixed savings. This means that have examined the crucial points of tax policy and public policy which are the best for the increase of consumption and of investments, subject to the case that there exists mixed savings in the maximum level. Therefore, follows an analysis which stands on the utility of the public sector and the utility of the uncontrolled enterprises. Thence, it is plausible to extract conclusions about the utility of the cycle of money, showing the points and the behaviors of any economy when there are mixed savings and escaped savings. For this analysis, the Q.E. method and its econometrical approach have been applied.
Rancang Bangun Alat Pendeteksi Uap Vaping dan Asap Rokok Berbasis Internet of Things Terintegerasi Aplikasi Android
Authors: Fuadi Hasani Rifqi , Nixon Benny , Humairah Alifa , Yasmin Augita
Published: November 2023

Merokok adalah suatu tindakan yang memicu penyakit terutama pada saluran pernafasan karena kandungannya yang tidak ramah untuk tubuh. Bagi seorang perokok pasif juga sangatlah dirugikan karena asap/uap yang terhirup. Maka dari itu, alat pendeteksi asap rokok dirancang dengan memanfaatkan fungsi jaringan WiFi yang tersambung dengan ESP32 yang akan mengirimkan data deteksi dari sensor MQ-2 (pendeteksi kandungan asap rokok tembakau) dan sensor Adafruit (pendeteksi kandungan uap rokok elektrik) menuju firebase yang terintegrasi dengan aplikasi android. Hal ini akan memudahkan bagi firma perhotelan karena alat ini tidak hanya dapat mendeteksi asap rokok tembakau saja, namun uap rokok elektrik pun juga akan terdeteksi sehingga tamu yang melanggar selain menggunakan rokok juga akan dapat dikenai denda yang mana akan dipantau oleh pegawai hotel tersebut secara jarak jauh melalui aplikasi android. Sistem dari alat ini khusus untuk sekali terdeteksi saja yang mana jika terdeteksi, maka LED dari hijau berubah menjadi kuning (rokok elektrik) jika sudah menyentuh ≥ 25 ppm dan/atau merah (rokok tembakau) jika sudah menyentuh ≥ 0,05 ppm yang diikuti dengan suara buzzer dan kipas DC yang akan membuang asap/uap keluar ruangan. Ruangan netral yang teruji selama 10 menit menghasilkan maksimal asap yang terdeteksi sebanyak 0,03 ppm dan uap yang terdeteksi sebanyak 24 ppm. Pada percobaan sensor MQ-2 dengan kadar 1 semburan menghasilkan 0,42 ppm dan delay selama 2 detik untuk sensor mendeteksi, pada ruang yang bervolume 1050 m3 kembali bersih dengan delay 11 detik dengan nilai 0,04 ppm. Pada percobaan sensor Adafruit dengan kadar 1 semburan menghasilkan 33 ppm, delay 2 detik untuk sensor mendeteksi, pada ruang yang bervolume 1050 m3 kembali bersih dengan delay 8 detik dengan nilai 24 ppm
Interference of Indonesian Language on Japanese Language in the Use of Aizuchi (相槌) by Japanese Language Students in Medan
Authors: Taulia  , Gapur Abdul
Published: November 2023

Language interference or disorder often occurs in individuals who have acquired proficiency in multiple languages, including Japanese language learners at the college level. This research aims to analyze the interference of the Indonesian language in the use of aizuchi (backchanneling) in Japanese by Japanese language students in Medan, Indonesia. The study employs a qualitative approach with a descriptive method. The data consists of transcriptions of conversations between students and lecturers that contain instances of aizuchi interference. Data collection is conducted through observation using techniques such as eavesdropping and note-taking. The collected data is analyzed through data condensation, data presentation, and conclusion drawing. The findings reveal that the interference of the Indonesian language in aizuchi in Japanese primarily occurs at the lexical level, specifically in the utilization of Indonesian words as aizuchi in Japanese conversations. An example of this interference is replacing the Japanese word "hai" with the Indonesian word "iya." The students' experiences influence the identified interference in learning foreign languages and cultural factors. This research contributes to a better understanding of the interference of the Indonesian language in the use of aizuchi in Japanese and provides insights for teaching the Japanese language at the tertiary level.
Die religiöse Verbrauch-Fetischismus: die Verwendung von Erfahrung in der christlichen religiösen Kontext
Authors: Modesto Junior Edson , Dendasck Carla Viana , Lee Gilead Ferreira
Published: November 2023

Religion war immer präsent in der Menschheit, da seine großen Bedeutung analysieren die religiösen Aspekt im Leben des Menschen wird etwas komplexer und umfassender. Diese Studie hat als Thema die Verwendung der christlichen religiösen Erfahrung. Die gegenwärtige Forschung versucht zu verstehen, wenn die Konsum-Erfahrung sich als Fetisch der Ware innerhalb der christlichen religiösen Welt präsentiert, wird im Rahmen des globalisierten Neoliberalismus und Konsumgesellschaft. Für die Durchführung solcher investigative Charakter explorative, qualitative Forschung, wird eine bibliographische Forschung, damit Erlangung eines einheitlichen theoretischen Rahmens, mit Sitz in den Sozial- und Naturwissenschaften Religion stattfinden.
ПІДПРИЄМНИЦТВО ЯК МУЛЬТИПЛІКАТОР ДІЛОВОЇ АКТИВНОСТІ У СТРАТЕГІЧНО ПРІОРИТЕТНИХ СФЕРАХ НАЦІОНАЛЬНОЇ ЕКОНОМІКИ, РЕГІОНУ Й ТЕРИТОРІАЛЬНОЇ ГРОМАДИ
Authors: Кубіній Наталія , Белей Наталія , Ножов Едвард
Published: November 2023

Доведено, що підприємництво доцільно розглядати як інструмент формування поточних та стратегічних конкурентних переваг для бізнесу, територіальної громади, регіону та національної економіки. Дослідження дозволяє стверджувати, що підприємництво виконує крім інших функцію мультиплікатора, тобто посилює активізацію діяльності у суміжних галузях економіки. Висвітлено, що найкращий результат буде отримано при інтеграції в межах одного підприємницького актора тих видів діяльності, що відносяться до стратегічних. Тому, інтеграція сільського господарства у вигляді фермерства та туризму в рамках одного підприємницького актора дозволяє останньому виконувати функцію мультиплікатора, що створює ефект синергії. Синергія в контексті даного дослідження – це явище, що відображає комбінований вплив підприємництва в туризмі з фермерством.
ВИКЛИКИ ТА ОРІЄНТИРИ ВІДНОВЛЕННЯ ЕКОНОМІЧНОГО ЗРОСТАННЯ РЕГІОНІВ УКРАЇНИ
Authors: Возняк Галина , Сороковий Данило
Published: November 2023

Ідентифіковано та оцінено виклики економічного поступу регіонів України в сучасних умовах, серед основних виокремлено такі: безпековий; поглиблення диференціації розвитку, втрати транзитного потенціалу; міграційна криза та євроінтеграційний курс України. Наголошено, що в умовах надмірної невизначеності важко вести мову про сценарії прогнозування розвитку чи відновлення регіонів України. «Реакція» на виклики лежить в площині врахування їх сили впливу, значимості для економіки та країни загалом і потребуватиме диференційованого втручання та скоординованих різних типів політик (фінансової, регіональної, галузевими). Аргументовано доцільність реагування та вирішення в рамках реалізації регіональної політики. Обґрунтовано орієнтири відновлення економічного зростання регіонів України. До таких запропоновано віднести: а)модернізацію структури економіки та відновлення інфраструктури, стимулювання економічної активності та сприяння інноваційному розвитку регіональних економік; б) розвиток системи багаторівневого врядування; в) узгодження та ефективна взаємодія систем управління регіональним розвитком в Україні та ЄС; г) формування нової державної регіональної політики розвитку різних функціональних типів територій. Наголошено на необхідності вибудовувати фінансову та регіональну політику таким чином, щоб, з одного боку, створювати правильні стимули та рівні умови для бізнесу, а отже і «запускати економіку» з врахуванням Маастрихтських критеріїв, з іншого – врахувати наслідки війни для розвитку територій, набуття Україною статусу кандидата на членство в ЄС тощо.