bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of exercise therapy on disability, mobility, and quality of life in the elderly with chronic low back pain: a systematic review and meta-analysis of randomized controlled trials
Authors: Zhang Shi-kun , Gu Mei-ling , Zhang Ting , Xu Hong , Mao Su-jie , Zhou Wen-sheng
Published: July 2023

Background

Exercise is an effective treatment in chronic low back pain (CLBP), but there are few studies on CLBP in the elderly, and the intervention effect is controversial. We aimed to compare the efficacy of different exercises therapy on CLBP, dysfunction, quality of life, and mobility in the elderly.

Methods

We searched Web of Science, MEDLINE, Cochrane Library, Chinese National Knowledge Infrastructure, EMBASE, and PubMed from the database inception till December 31, 2022. The publication languages were Chinese and English. Randomized controlled trials (RCTs) of exercise intervention in the elderly (≥ 60 years) with CLBP were included. Two reviewers independently extracted the data and evaluated them using the Revised Cochrane Risk of Bias Tool for Randomized Trials 2 (RoB2). The pooled effect sizes on different aspects of outcome measures were calculated.

Results

Sixteen articles (18 RCTs) were included, comprising a total of 989 participants. The quality of included studies was relatively high. Meta-analysis results indicated that exercise therapy could improve visual analog scale (VAS) (WMD = − 1.75, 95% CI − 2.59, − 0.92, p < 0.05), Oswestry disability index (ODI) (WMD = − 9.42, 95% CI − 15.04, − 3.79, p < 0,005), short-form 36-item health survey physical composite summary (SF-36PCS) (WMD = 7.07, 95% CI 1.01, 13.14, p < 0.05), short-form 36-item health survey mental composite summary (SF-36MCS) (WMD = 7.88, 95% CI 0.09, 15.67, p < 0.05), and timed up and go test (TUG) (WMD = − 0.92, 95% CI − 2.22, 0.38, p < 0.005).

Conclusion

Exercise therapy effectively improved VAS, ODI, and SF-36 indexes in the elderly. Based on the subgroup, when designing the exercise therapy regimen, aerobics, strength, and mind–body exercise (≥ 12 weeks, ≥ 3 times/week, ≥ 60 min) should be considered carefully, to ensure the safety and effectiveness for the rehabilitation of CLBP patients. More high-quality trials are needed in future to confirm the effect of exercise on SF-36 and TUG indexes.
The impact of body mass index on the pregnancy outcomes and risk of perinatal depression: Findings from a multicenter Italian study
Authors: Ventriglio Antonio , Severo Melania , Petito Annamaria , Nappi Luigi , Iuso Salvatore , Altamura Mario , Sannicandro Valeria , Milano Eleonora , Arcidiacono Giulia , Di Salvatore Melanie , Gallone Fiammetta , De Masi Laura , Marconcini Alessia , Giannaccari Elisa , Maruotti Giuseppe , Palma Giuseppe Luigi , Vicino Mario , Perrone Antonio , Caroli Antonella , Di Pinto Isabella , Bellomo Antonello
Published: July 2023

Background

Body Mass Index (BMI) is an informative factor on body fatness which has been associated to higher levels of Perinatal Depression (PD) and complications during pregnancy. We aimed to explore the impact of pre-pregnancy and postnatal BMI on the risk of Perinatal Depression and pregnancy outcomes among women recruited at their third trimester of pregnancy.

Methods

We report on findings from a large multi-centre study conducted in the South of Italy and involving 1611 women accessing three urban gynaecological departments from July to November 2020. Pregnant women were assessed at their third trimester of pregnancy (T0) and after the childbirth (T1) ;The Edinburgh Postnatal Depression Scale (EPDS) has been employed for the screening of PD over time (T0 and T1) as well as other standardized measures for neuroticism, resilience, and quality of life at baseline. BMI (T0 and T1) and other socio-demographic and clinical characteristics have been collected.

Results

Over-weight and obesity (higher levels of BMI) were associated with higher risk of PD (higher scores of EPDS), higher neuroticism and poorer subjective psychological well-being among enrolled women. Also, obesity and over-weight were associated with lower education, higher number of physical comorbidities, medical treatments and complications during pregnancy.

Conclusions

Over-weight and obesity may impact on mental health and pregnancy outcome of women enrolled. Psycho-educational interventions aimed to improve the management of physical and emotional issues may reduce the risk of PD and complications during pregnancy.
Evidence-based policymaking in the legislatures: timeliness and politics of evidence in Finland
Authors: Aula Ville
Published: July 2023

Scholarship on evidence-based policymaking (EBP) has long called for more a realistic understanding of how politicians use evidence, especially the ways that use of evidence is negotiated with political goals. This article offers a new perspective on this question by drawing from research on legislative organisations. It introduces a new framework for the study of evidence-based policy, developed by reviewing key insights from legislative studies and interpreting their relevance for the study of EBP. It then applies this framework in an interview-based case-study of the Parliament of Finland. Previous studies have identified timeliness and relevance as some of the key barriers to using evidence, and our data focus on how key actors in legislative organisations understand and manage timeliness. Our findings show that timeliness is dominated by short-term reactions to new bill proposals, but the window for timely evidence in the legislatures can vary from months to days. Our study identifies three strategies used in legislative organisations to overcome the problems of reactivity: programmatic work, specialisation and network building. Practices relating to these strategies are discussed across legislators, political parties and committees. Our findings suggest that it is important for research on EBP in a legislative context to go beyond the study of committees and individual legislators, to explore the role of political parties. This strategy allows researchers to discover the often non-linear and indirect ways that evidence can influence policy through political parties.
Assessing afebrile malaria and bed-net use in a high-burden region of India: Findings from multiple rounds of mass screening
Authors: Garg Samir , Gupta Vishnu , Patel Kavita , Dewangan Mukesh , Nanda Prabodh , Sridhar Ryavanki , Singh Gajendra
Published: July 2023

A key obstacle in the fight against malaria is afebrile malaria. It remains undiagnosed and, therefore, is invisible to the health system. Apart from being a serious illness, it contributes to increased transmission. Existing studies in India have not adequately reported afebrile malaria and its determinants, including the use of long-lasting insecticide-treated nets (LLINs). This study used six waves of mass screening, which were conducted by the state government in the high-malaria-burden region of Chhattisgarh, a state in India, in 2020, 2021, and 2022. Each round of data collection included more than 15000 individuals. Descriptive statistics were used to analyse key indicators of malaria prevalence and LLIN use. Multivariate analyses were performed to identify the determinants of afebrile malaria and LLIN use. Malaria prevalence in the afebrile population varied from 0.6% to 1.4% across the different waves of mass screening. In comparison, malaria positivity among febrile individuals was greater than 33% in each wave. Afebrile malaria contributed to 19.6% to 47.2% of the overall malaria burden in the region. Indigenous communities (scheduled tribes) were more susceptible to malaria, including afebrile malaria. Individuals using LLINs were less likely to be affected by afebrile malaria. Overall, 77% of the individuals used LLINs in early monsoon season, and in winter the rate was lower at 55%. LLIN use was significantly associated with the number of LLINs the households received from the government. Although fever continues to be a primary symptom of malaria, afebrile malaria remains a significant contributor to the malaria burden in the region. The free distribution of LLINs should be expanded to include high-burden populations. Global policies must include strategies for surveillance and control of afebrile malaria in high-burden areas.
A escrita da História da Educação nos manuais de ensino: indícios da biblioteca de formação no Curso de Pedagogia da UEL de 1962 a 1998
Authors: Favaro Marta Regina Gimenez
Published: July 2023

Esse texto apresenta o que foi referência na biblioteca de formação da disciplina História da Educação (HE) no Curso de Pedagogia da Universidade Estadual de Londrina, no período de 1963 a 1998. A metodologia utilizada foi a pesquisa documental, tendo como fonte 47 programas da disciplina, assim distribuídos: 16 programas de 1963 a 1970; 24 de 1972 a 1991; e 7 de 1992 a 1998. O texto estrutura-se recenseando o material utilizado no ensino da HE e, neste, a localização dos manuais mais recorrentes. No caso específico da UEL, a biblioteca de formação consistiu em categoria presente em todos os programas consultados. A composição do ensino de HE apropriou-se da formatação de conteúdo e da periodização dos manuais indicados como recorrentes, confirmando a rede que se estabeleceu entre formação acadêmica do professor, sua biblioteca de formação, os manuais disponíveis, a inserção nos círculos acadêmicos e as relações institucionais.
Revista Folha da Serra: a imprensa, a cidade, a educação e a biblioteca no sul do Mato Grosso na década de 1930
Authors: Massirer Jaíne da Silva , Silva Arlene Maria Ribeiro
Published: July 2023

Na obra “Educação e imprensa: Folha da Serra – Revista Mensal ilustrada”, as pesquisadoras Eglem de Oliveira Passone e Kênia Hilda Moreira investigam as dimensões educativas de um impresso não pedagógico, do gênero revista ilustrada, a Folha da Serra, produzida na cidade de Campo Grande, sul do antigo estado de Mato Grosso , a qual, durante seus dez anos de existência, publicou 48 números, entre aos anos de 1931 e 1940. No prefácio, Adriana Aparecida Pinto brinda leitoras e leitores com um fragmento da escrita de Manoel de Barros, que possibilita a reflexão sobre as palavras e a sua força. Destaca, assim, importantes aspectos do livro que “[...] evidencia um coletivo de adjetivos que seria difícil precisar, dada a sua relevância para o cenário de pesquisas históricas em educação da região Centro-Oeste” (PINTO, 2021, p. 10). Ademais, ressalta como, a partir das marcas de leituras, as autoras tecem uma análise atenta e sensível, dando a ler os temas: imprensa, cidade, educação e biblioteca. Como apontado por Adriana Pinto, a estrutura da organização dos capítulos desse livro pode ser lido individualmente ou no conjunto da obra.
Design of mountain fire prevention monitoring system for transmission lines based on machine vision algorithms
Authors: Dong Shunhu , Ding Yuanjie , Ma Lishan , He Wei , Lei Xiaoping
Published: July 2023

With the continuous development of society, power grid has become a major guarantee for social and economic development, and its coverage is also expanding. The power grid not only covers some developed areas, but also extends to remote mountainous areas with complex changes in geological and climatic conditions. However, at the same time, line failures and power outages caused by mountain fires are becoming increasingly frequent, which poses a significant threat to the safety and stable operation of the power system. Therefore, how to solve the problem of mountain fire on transmission lines has become an important topic today. The main purpose of this study is to achieve effective monitoring of transmission line mountain fires and provide more assurance for the stable operation of the power system. This article discussed the transmission line and traditional mountain fire prevention monitoring system, and combined the current hot machine vision algorithm to design the overall mountain fire prevention monitoring system, focusing on analyzing the differences between this system and traditional systems. Through experiments, it was found that the monitoring accuracy of the mountain fire prevention monitoring system designed in this article has been improved by 10.6 % compared to the traditional system at location 4, 7.6 % at location 6, and 7.9 % at location 7. At the same time, the real-time performance and anti-interference performance of this system were also better than traditional systems, and the overall performance of the system was better. Practice has proved that the system can effectively overcome the interference of external environment, and monitor and identify the fire situation in real time and accurately, ensuring the safety of transmission lines. At the same time, the research on machine vision algorithms in this paper can also help promote the more perfect development of power systems. Practice has proved that this system can effectively overcome the interference of the external environment, and continuously and accurately detect and identify the fire situation.
Are lignocellulosic resources too valuable to burn?
Authors: Hubbe Martin A.
Published: July 2023

Lignocellulosic matter often can be counted as a renewable resource, since it is produced by photosynthesis. But there are limits to how much biomass our society can use in a sustainable manner. People can debate whether or not it makes sense to use a substantial portion of lignocellulosic materials as a source of liquid fuel. This essay gives a qualified affirmative answer to the question in its title. However, combustion of lignocellulosic resources can be considered as wasteful and uneconomical, in the long run, if it is inefficient, if it fails to displace the combustion of fossil fuels, or if it displaces a higher-end use, for which there are available customers. In particular, it seems unlikely that combustion of fuels derived from lignocellulosic biomass can, by itself, solve problems that stem from society’s excessive thirst for motor fuels.
Drill wear during the boring of particle board: A multi-factor analysis including effects of mineral contaminants
Authors: Porankiewicza Bolesław , Wieloch Grzegorz
Published: July 2023

This paper evaluates and discusses multifactor non-linear, statistical dependencies of drill side-edges recession VBK and drill diameter recession delta DW on the cutting path length LC, the content of hard mineral contaminants CMC, the size of contaminant particles SMC, and the Mohs hardness MH. Significant influence of the cutting path LC, the content CMC of hard mineral contaminants (HMC), and the size of contaminant particles SMC was found, whereas the Mohs hardness MH of the contamination particles was less important.
Synthesis and characterization of hierarchically porous silica with poplar tissue as template with assistance of supercritical CO2
Authors: Ni Wei , Chen Jiafu , Xu Qun
Published: July 2023

Hierarchically porous silica samples, ranging from mesopores to macropores, were prepared by “nanoscale casting using supercritical (SC) fluids” (NC-SCF) technology and bionics, achieving a biomineralization process in an environmentally friendly and efficient way. These wood-templated SiO2 samples, having special hierarchical pore sizes from 3.3 nm up to 50 μm, were obtained with SC-CO2 precursor solution by a wood-silication method. For this method, the precursor, tetraethyl orthosilicate (TEOS), was dissolved in SC-CO2 and impregnated into poplar tissue cells using SC-CO2 as a mass carrier. After removal of the wood template by calcination in air at suitable temperatures, the porous silica was obtained. The effects of CO2 pressure and precursor concentration on the impregnating ratio were studied, and the products were characterized. SEM experimental results showed that the obtained silica had the same external and internal structures of the original wood. XRD and N2 absorption-desorption results indicated that the silica was amorphous but crystallized with the calcination temperature up to 1000 oC, and had a preferable BET surface area being up to 469 m2/g (600 oC). So this work provides a simple and timesaving route to obtain and control the special microstructure of silica with the aid of a wood template in supercritical CO2.
Odbudowa prawosławnej sieci parafialnej na Łemkowszczyźnie po 1956 roku jako element wielokulturowości regionu
Authors: Dudra Stefan
Published: July 2023

W wyniku powojennych przesiedleń (1944–1946) na tereny USRR, a następnie na Ziemie Odzyskane w ramach akcji „Wisła” (1947 r.) życie religijne prawosławnych Łemków na obszarze Łemkowszczyzny przestało istnieć. W większości zabytkowe świątynie wraz z wyposażeniem uległy zniszczeniu. Mienie cerkiewne zostało rozgrabione. Proces odbudowy prawosławnej sieci parafialnej rozpoczął się po 1956 r. Jego efektem było powołanie już w 1959 r. dekanatu rzeszowskiego. Odradzanie się struktury parafialnej napotykało liczne utrudnienia. Wśród najważniejszych należy wymienić nieprzychylne stanowisko lokalnych władz wyznaniowych, zły stan przekazywanych świątyń, brak duchowieństwa. Jednak do końca lat 60. XX w. udało się stworzyć sieć parafialną, która zaspokajała potrzeby religijne wiernych. Kluczowym momentem dla rozwoju i stabilizacji życia religijnego było erygowanie w 1983 r. diecezji przemysko-nowosądeckiej. W wyniku przemian demokratycznych dokonujących się w Polsce po 1989 r. Cerkiew prawosławna rozpoczęła nowy okres w swojej działalności. Poza elementami integracyjnymi, ze względu na pojawiające się możliwości, mogła w szerszym zakresie wypełniać swoją funkcję kulturotwórczą i stawać się istotnym elementem wielokulturowości regionu.
Normativity of virtual communication in the expression of a negative evaluation
Authors: Uskova Olga A. , Gritsenko Alina A.
Published: July 2023

The study is devoted to the problem of the virtual language communication normativity, namely the specifics of expressing a negative assessment. It is proved that the formation of the norm of language communication occurs in the system of taxa “norm – non-normal – anti-norm” (according to the concept of V.G. Kostomarov). It is substantiated that the virtual language communication normativity is not a direct reflection of the real language environment normativity, but is formed under the influence of the virtual environment communication stereotypes characteristics, which have significant differences from the current national communication stereotypes adopted in the Russian society. It has been established that a negative assessment in a virtual environment acts as a means of verbal aggression due to the absence of restrictions in the language means choice by which the intention of a negative assessment is verbalized in virtual communication situations that are aimed at achieving extralinguistic communication goals related to the communicant’s self-affirmation with the help language means of taxa non-norm and anti-norm, the exclusive right presumption to an interlocutor negative assessment (verbalization of the insult intention), the rejection of the opponent’s point of view, manifested in the absence of intentions of the interlocutors to seek a compromise. The results of the study allow us to state the special conditions presence for the formation of specific norms of language communication in a virtual communication environment.
Adaptive Identification Method for Vehicle Driving Model Capable of Driving with Large Acceleration Changes and Steering
Authors: Matsumoto Soichiro , Saito Mitsuyuki
Published: July 2023

In the future, considering the expansion of the autonomous driving society, autonomous driving systems that can drive safely and quickly will be required for the purpose of saving lives and transporting goods even on rough road such as snowy, icy, and unpaved roads. In such unknown environments, technologies that combine model-based control and artificial intelligence (AI) are attracting attention for the purpose of ensuring operational stability and reliability. The second author has proposed a vehicle driving model that is robust to road geometry and ever-changing environmental disturbances. This model is based on a two-wheel model, and expresses the error in the position of the center of gravity of the vehicle by the front wheel steering angle deviation, and adaptively estimates this deviation. However, this model has large modeling errors when driving at high velocity on slippery roads. In this study, we extend this model proposed in previous study, and propose a new vehicle driving model that can handle situations such as driving with large acceleration changes and steering on bad roads such as snowy and wet roads. Then, we demonstrate the usefulness of the proposed method in a simulation using vehicle motion analysis software.
Lack of regular physical activity and adequate sleep are risk factors for musculoskeletal pain in medical college students - a cross-sectional study
Authors: Zheng Lianshuai , Rong Xueyuan , Meng Yao , Jiao Lina , Cui Jizheng
Published: July 2023

Background
During January-May 2020, novel coronavirus outbreak occurred in East China, and many medical college students, implemented a home protection policy, resulting in significant changes in their physical activity and lifestyle habits. This work aims to analyze the effects of usual physical activity habits, changes in physical activity and lifestyle habits during home protection on the occurrence of musculoskeletal pain from multiple perspectives, and to provide new clues for the search of risk factors for musculoskeletal pain and alternative solutions for the prevention.
Methods
A cross-sectional study was conducted using questionnaires from 900 randomly selected medical students who had taken home protection between January and May 2020 from four medical universities in East China. Participants completed surveys on socio-demographic characteristics, days of home protection, physical activity in daily life, changes in physical activity during home protection, and daily routine, and reported the location of musculoskeletal pain during home protection. Pain was assessed using Visual Analogue Scale (VAS) scores, and considered to be present if the VAS score > 0. The questionnaire data were double-checked and entered into Epi Data 3.0 to create a database, and SPSS 19.0 was used for statistical analysis. The correlation between measures and musculoskeletal pain was determined using the Mann-Whitney U test, and the correlation between categorical variables and musculoskeletal pain was determined using the chi-square test, and multi-factor logistic regression analysis was used to remove confounding factors and screen for risk factors. The test level was set at α = 0.05.
Results
The prevalence of musculoskeletal pain during home protection was 40.2% (n = 345; 95% CI 36.9%-43.4%). Multi-factor logistic regression analysis revealed that the females (OR 1.391; 95% CI 1.006–1.922), irregular physical activity in daily life (OR 1.648; 95% CI 1.157–2.347), and less than 6 hours of sleep per day during home protection (OR 1.474; 95% CI 1.020–2.131) were found to be risk factors for musculoskeletal pain.
Conclusions
Female medical students should pay more attention to the prevention of musculoskeletal pain; regular physical activity in daily life and sufficient sleep time may prevent the occurrence of musculoskeletal pain.
Impact of UV-C irradiation on storage pests with different ecological functions and the viability of the treated grains
Authors: Keszthelyi Sándor , Gibicsár Szilvia , Somfalvi-Tóth Katalin , Pál-Fám Ferenc
Published: July 2023

This study was carried out on the effects of different exposures of UV-C irradiation (253.2 nm) (5, 10, 15, 20 and 25 mins) on the mortality of stored product pests: Sitophilus granarius L. (Coleoptera: Curculionidae) as a primary pest, Tribolium castaneum (Herbst) (Col.: Tenebrionidae) and Cryptolestes ferrugineus (Stephens) (Col.: Laemophloeidae) and Oryzaephilus surinamensis (Ganglbauer) (Col.: Silvanidae) as secondary pests. Besides, the viability of treated maize and wheat seed items influenced by UV-C irradiation was analysed by tetrazolium test. Our results confirmed the treatment that leads to total mortality is inversely proportional to the exposure to UV-C radiation. The time of total mortality during the post-treatment period as a function of radiation exposure can be characterised by a power-like trend line for each examined insect species. Our results confirmed the insecticidal efficacy and the sensitivity of pest species with different ecological functions to UV-C irradiation. The primary species in the crop treated by shorter exposure (10 mins of UV-C at a distance of 22 cm) may prevent the introduction of secondary stored product pests enter later. The tetrazolium test showed that the wheat seeds were more sensitive to this physical stress than maize seeds in a similar condition. Values of the recorded viabilities fluctuated highly. The effects of UV radiation on treated wheat and maize seeds are somewhat controversial. However, this pest elimination technique is primarily recommended in environments exempt from viable stored seeds because the intactness of treated seeds cannot be demonstrated.
Trichopria anastrephae as a biological control agent of Drosophila suzukii in strawberries
Authors: Kruger Alexandra Peter , Garcez Amanda M. , Scheunemann Tiago , Nava Dori E. , Garcia Flávio Roberto Mello
Published: July 2023

In South America, the resident pupal parasitoid Trichopria anastrephae Costa Lima (Hymenoptera: Diapriidae) is a potential biological control agent of the pest Drosophila suzukii Matsumura (Diptera: Drosophilidae). In the present study we 1) examined the behavior of T. anastrephae towards different host (D. suzukii) and host-substrate (strawberry) cues in choice and non-choice bioassays in laboratory, and 2) examined the density-dependent parasitism of T. anastrephae in D. suzukii-infested strawberries in a greenhouse. We tested infested and non-infested strawberries for the behavioral assays in a four-chamber olfactometer. For the greenhouse bioassay, we set five walk-in cages with strawberry plants in a greenhouse, released D. suzukii adults, and then released different numbers of parasitoids (0, 60, 120, 240, and 360) in each cage. In non-choice bioassays, female parasitoids showed a preference towards D. suzukii-infested strawberries containing larvae, pupae or inoculated pupae, or healthy overripe fruits. When given a choice, female parasitoids walked longer over chambers with fruits infested with eggs, larvae, or pupae of D. suzukii, when compared to healthy uninfested strawberries, and over overripe fruits when compared to unripe or ripe fruits. In the greenhouse assay, we observed an increase in parasitism and a decrease in the number of D. suzukii emerging per fruit with an increase in the number of parasitoids released. Our results allow a better understanding of the behavior and parasitism of T. anastrephae in D. suzukii-infested strawberries and provide useful data for potential biological control programs using this parasitoid.
Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study
Authors: Joinson Carol , Grzeda Mariusz T. , Heron Jon , Gontard Alexander
Published: July 2023

Objective
To examine if sleep duration and sleep problems are associated with urinary incontinence (UI) in children.
Methods
We used multinomial logistic regression to examine the association of child sleep duration/problems at 3½ years with developmental trajectories of bedwetting and daytime wetting from 4–9 years in 8,751 (4,507 boys and 4,244 girls) from the Avon Longitudinal Study of Parents and Children. We adjusted for sex, socioeconomic indicators, mothers’ emotional/practical/financial support, developmental delay, stressful life events, temperament, and emotional/behaviour problems.
Results
Preschool children who slept more than 8½ hours per night had a decreased probability of UI at school-age. There was a 33% reduction in odds of daytime wetting per additional hour of sleep (odds ratio [OR] = 0.67, 95% confidence interval [CI] = 0.52–0.86). Sleep problems were associated with increased odds of daytime wetting (e.g., getting up after being put to bed: OR = 2.20, 95% CI = 1.43–3.39), delayed bladder control (e.g., breathing problems whilst sleeping: OR = 1.68, 95% CI = 1.12–2.52), and persistent (day and night) wetting (e.g., night-time waking: OR = 1.53, 95% CI = 1.16-2.00). Waking during the night and waking up early in the morning were associated with reduced odds of bedwetting at school-age (OR = 0.76, 95% CI = 0.61–0.96 and OR = 0.80, 95% CI = 0.64–0.99 respectively).
Conclusions
Preschool children who sleep for longer have a lower likelihood of UI at school-age, whilst those with sleep problems are more likely to experience daytime wetting and combined (day and night) wetting, but not bedwetting alone. Short sleep duration and sleep problems in early childhood could be indicators of future problems attaining and maintaining bladder control.
Site Response Analysis by Generating a New 3-d Mesh Design With Surface Topography: a 3-d Site Response Analysis of Northwest Turkey
Authors: Doğan Ayhan , Dikmen Ünal
Published: July 2023

Predicting soil behavior under dynamic load due to earthquakes is pivotal for engineering structures and human life. Due to various limitations, such as insufficient computers and difficulties in generating models, the third dimension effect is generally neglected in many studies. Conversely, the third-dimension effect in regions with high topographic differences, deep basins, 3-D heterogeneous and anisotropic environments, and alluvium is at a level that cannot be neglected. This study created a three-dimensional model of the northwest of Turkey for the first time by including surface topography. Soil properties were added to this model, and dynamic analysis was performed. The accuracy of this model was analyzed using real earthquake data recorded in the study area. In addition, a new software (SiteEffect3D) with various features has been developed to create a 3-D mesh with topography using digital elevation model data and to perform dynamic analysis more effectively. This software has been tested comparatively with Plaxis 3D software using synthetic terrain models. The importance of this study is that in addition to its contributions to site response analysis and seismic hazard assessment, new software has been developed that can be used in similar studies. This new model aims to increase the accuracy of ground motion predictions in Northwest Turkey. The findings will provide valuable information for seismic design and construction practices and facilitate the development of more effective strategies to reduce the potential damage from earthquakes in the region.
Evaluation of Lipid Transfer Protein (Ltp) 1 Gene in Sesame and Other Plants Using Bioinformatics Approach
Authors: Edu Ndem E. , Ugorji Udensi O. , Agada Francis Ndagerang , Ubi Godwin M. , Agbor Reagan B.
Published: July 2023

This study was aimed at using bioinformatics tools to characterize the Lipid Transfer Protein 1 gene in some selected accessions with special reference to Benny seed (Sesamum indicum) Lipid Transfer Protein 1 sequence as a query sequence. Nucleotide and amino acid sequences of 30 accessions were retrieved from NCBI database and analyzed for homology, physicochemical properties, motifs, GC content as well as phylogenetic relationships. Results showed that nucleotide and amino acid sequence lengths of this gene among the selected accessions differs. Its nucleotide length varied between 599–8461bp, while the amino acids sequence varied between 96–355 residues, Molecular weight range from 10008.77–35532.61daltons. With Sesamum indicum having the lowest molecular weight and Physcomitrium patens having the highest molecular weight. Result on the Theoretical PI was above 4.61 for all the amino acid sequences of Lipid Transfer Protein 1 gene in the selected accessions. It was observed that the total number of negatively charged residues ranged from 1–20. The instability index and aliphatic index ranged from 20.23–69.39, 73.48–102.24 respectively. Some of the proteins are stable, while twelve were considered unstable following the results for instability index. Extinction coefficient was highest for Sesamum indicum (14480). Daucus carota subsp. Sativus (-0213) is the only accessions with a negative GRAVY. The motifs N-glycosylation site, Plant lipid transfer proteins signature, N-myristoylation site, Casein kinase II phosphorylation site, Protein kinase C phosphorylation site were the most common across the selected accessions. GC content analysis revealed that it ranged from ranged from 29.73–54.55%. Analysis of the secondary structure of the amino acid sequences of the Lipid Transfer Protein 1 gene showed that the region covered by random coil was the highest in the sequences compared to alpha helix and extended strand. Alpha helix ranges from 33.11–54.31%, the extended strands ranged from 9.17–15.13%, while the random coil ranges from 32.77–51.16% across the accessions. Following the results of the present study, it can be concluded that Lipid Transfer Protein 1 gene sequence of Sesamum indicum is closely related to Lipid Transfer Protein 1 gene in Brachypodium distachyon and distant to that in Glycine max, Vigna unguiculata, Capsicum annum.
Let’s Explain Crisis: Deep multi-scale
Hierarchical Attention framework for
Crisis-task Identification
Authors: Priya Shalini , Joshi Vaishali , Chandra Joydeep
Published: July 2023

Emergency services rely heavily on Twitter for early detection of crisis tasks to enhance crisis management systems. However, employing state-of-the-art models often face data sparsity as well as their inadequacy to handle long-range dependencies between tweet tokens. Additionally, the authorities need to gain confidence in the model's prediction so that the detected task information can be better believed and prioritized.
In this study, we present a generalized framework named Explainable Attentive model for Crisis Task identification (ExACT) to handle the above mentioned challenges while identifying crisis task relevant tweets as well as provide the model explainability by utilizing a very small corpus of tweets. The novelty of ExACT is three-fold: (1) Data enrichment has been introduced by non-dynamic contextual attributes derived from tweets to overcome the sparsity. (2) Feature enrichment has been incorporated using hierarchical attention at both local and global levels using residual self-attention and correlation attention to capture long-range dependencies. (3) LIME based model explainability approach added to understand the task important tokens. Experiments reveal that ExACT has a competitive performance improvement over various state-of-the-art models in terms of F-measure (20% and 14% respectively) and accuracy (14% and 16% respectively) across two different crisis tasks infrastructure damage and support signal identification. Consistent performance improvement for two different tasks considered from publicly available crisis event datasets depicts the model's generalizability. While LIME supported explainable mechanism in ExACT can identify the important keywords but does not guarantee a high score in terms of plausibility and faithfulness metrics.
Predictors and components of inpatient asthma hospital cost: a retrospective cohort study. Analysis from a sample of 14 Belgian hospitals
Authors: Seret Jehan , Bruyneel Arnaud , Larcin Lionel , Gooset Fabienne , Azzi Djohra , Martins Dimitri , Bulcke Julie Van Den , Leclercq Pol , Pirson Magali
Published: July 2023

Background
Addressing the challenges of asthma has involved various approaches, including the examination of costs associated with hospitalization. However, there is a limited number of studies that have investigated the actual expenses incurred by hospital settings in caring for asthma patients. This study aims to describe the costs, predictors, and breakdown of expenditures in different categories.
Methods
A retrospective cohort study was conducted, involving 314 hospital stays of patients over 12 years old who were admitted for asthma and classified under APR-DRG 141 (asthma). Univariate and multiple linear regression analyses were performed.
Results
The median cost, regardless of DRG severity, amounted to 2.314€ (1.550€-3.847€). Significant variations were observed when the sample was stratified based on the severity of DRG, revealing a cost gradient that increases with severity. The length of stay followed a similar trend. Six predictors were identified: age, admission to intensive care, asthma severity, severity level of the DRG, winter admission, and length of stay. The cost breakdown showed that 44% constituted direct costs, 25% were indirect costs, 26% were attributed to medical procedures performed outside the patient unit, and 5% were related to medication administration.
Conclusions
This study initiates a discussion on the role of reducing hospital costs in strategies aiming at controlling asthma-related costs. We argue that cost reduction cannot be achieved solely at the hospital level but must be approached from a public health perspective. This includes promoting high-quality outpatient care and addressing factors leading to poor adherence to the care plan.
The state of the colon microbiome in women with gestational diabetes
Authors: Djuryak V.S. , Mikheev A.O. , Sydorchuk L.I. , Pankiv I.V.
Published: July 2023

Background. Gestational diabetes is a condition that arises due to impaired metabolic processes against the background of insulin resistance and an increase in blood glucose levels during pregnancy. This pathology leads to a significant number of pregnancy and childbirth complications, high child perinatal morbidity and mortality, and its prevalence varies throughout the world. The aim of the work was to determine the taxonomic composition, population level and microecological indicators of the macroorganism-microbiome ecosystem of the symbiotic colon microbiota in women with gestational diabetes. Materials and methods. The microbiological examination of the colon contents was carried out in 26 pregnant women aged 18 to 35 years. The clinical material for microbiolo­gical examination was the fresh colon contents (faeces) taken from medium portions, which were collected in sterile (after autoclaving) vials. Results. According to the results of the work, it was found that during gestational diabetes, the taxonomic composition and microecological parameters of the macroorganism-microbiome ecosystem of the colon microbiota in women are impaired due to the biotope contamination with pathogenic microorganisms (E.coli HLy+) and opportunistic pathogens (E.coli Lac-, P.mirabilis, P.vulgaris, E.cloacae, C.diversus, S.marcescens), enterobacteria, C.albicans, P.niger and bacteria of the genus Clostridium. Alterations in the taxonomic composition and microecological indicators of the colon microbio­me in women with gestational diabetes lead to multidirectional changes depending on the taxon: a decrease in the population level of bacteria, which are the most important in terms of representation in the human colon microbiome, with a multifunctional role in maintaining microecological homeostasis (bacteria of the genus Bifidobacterium — by 17.59 %, Lactobacillus — by 38.37 %) and an increase or a stable trend towards an increase in the population level of opportunistic enterobacteria P.mirabilis by 26.67 %; among other enterobacteria, the population reaches high levels (from 6.390 ± 0.009 lg CFU/g to 7.46 ± 0.17 lg CFU/g), the level of Staphylococcus in increased by 35.94 %, C.albicans — by 26.74 %, P.melaninogenicus — by 55.93 %.
Hormonal imbalance in patients with chronic kidney disease in the pre-dialysis and dialysis periods (part 2)
Authors: Katerenchuk I.P. , Rustamyan S.T. , Talash V.V. , Yarmola T.I.
Published: July 2023

In the previous article, we presented the results of literature review showing the changes in hormone concentrations (parathyroid hormone, insulin, growth factor, prolactin) in patients with chronic renal failure (CRF) at the pre-dialysis and dialysis stages, described pathological relationships between renal failure and serum hormones concentrations, as well as changes in their biological effects. In this article, that continues the general topic, we provide the results of literature review that shows changes in serum concentrations of thyroid, adrenal, sex hormones and the features of the functioning of hypothalamus-pituitary-peripheral glands axis in patients with CRF. The presence of close pathogenic interactions of renal functional condition with hormonal activity of the thyroid gland was evaluated, as well as the ability of thyroid gland to influence the CRF progression both during pre-dialysis and dialysis sta­ges of CRF. Most patients with CRF have low serum triiodothyronine and thyroxine levels. It means that CRF is a pathological condition associated with thyroid hypofunction that progressively worsening as glomerular filtration rate decreases. For patients receiving dialysis treatment, hypothyroidism is associated with higher mortality. Secondary adrenal insufficiency is usually progresses in patients on renal replacement therapy. Non-diagnosed chronic adrenal failure may be life-threating that’s why the analysis of adrenal function is especially actual for patients on both pre-­dialysis and dialysis stages of CRF. Secondary adrenal insufficiency caused by long-lasting treatment with corticoids is a diagnostic problem for patients on dialysis treatment, because many nephrological diseases are treated by corticoids, and immunosuppressive therapy protocols used after the kidney transplantation are usually include prednisone. As the endocrine dysfunction progresses in patients with CRF, sexual dysfunction develops due to sex hormone imbalance. Abnormal androgen concentration is a typical fin­ding in CRF. A negative correlation was found between endogenic testosterone concentration and CRF stages I–V that indicated an abnormal profile of male sex hormones. There are gender-specific features of the development and progression of clinical symptoms of hormonal imbalance. The number of experimental studies show that continuous estradiol treatment may prevent the development of glomerulosclerosis. The results of clinical trials concluded that lower CRF progression and the lower incidence of CRF observed in young females compared to males, as well as the absence of gender protection in post-menopausal period, shows the important role of female sex hormones.
Procesy restrukturyzacyjne charakteryzujące rynek cukru w Unii Europejskiej
Authors: Budzyńska Anna
Published: July 2023

Na rynku cukru występuje zjawisko silnej konkurencji międzynarodowej. W Unii Europejskiej przemysł cukrowniczy należy do podstawowych działów przetwórstwa rolnego. Od momentu powołania Wspólnoty do końca ubiegłego stulecia jej członkowie byli głównymi producentami cukru na świecie. W ciągu pierwszej dekady XXI wieku znaczenie unijnego cukru w międzynarodowej wymianie handlowej zmalało. To wymusiło zmiany na unijnym rynku cukru. Od 2006 roku Unia Europejska prowadzi reformę systemu regulacji rynku cukru, której celem jest przygotowanie unijnego rynku cukru na całkowitą liberalizację międzynarodowej wymiany handlowej oraz poprawa konkurencyjności unijnego rynku cukru. Powyższe zmiany będą miały znaczący wpływ na opłacalność produkcji oraz zmierzają do poprawy konkurencyjności produkcji cukru w Unii Europejskiej. Z tego powodu nie jest możliwe przeprowadzenie reformy bez jednoczesnej głębokiej restrukturyzacji i modernizacji sektora cukrowniczego.
Environmental Benefits of Green Buildings with BIM Technology
Authors: Jiang Liting
Published: July 2023

Under accelerated urbanisation and rapid social and economic development, environmental pollution has become an important content of the construction industry. Therefore, the environmental benefit analysis of green buildings is of great significance to the effective use of energy and resources and to achieve the goal of protecting resources, reducing pollution and improving the ecological environment. The results show that the measured results of incremental environmental costs of the office building in Taiyuan City in land saving, energy saving, water saving, material saving, indoor environmental quality and operation management are decreased by 13.56 %, 11.02 %, 25.17 %, 14.43 %, and 15.25 %, respectively; incremental environmental benefits in land saving, energy saving, water saving, material saving, indoor environmental quality and operation management are increased by 23.15 %, 10.37 %, 19.30 %, 18.25 %, and 22.53 %, respectively. Those suggest that the BIM technology applied to the complete life cycle cost analysis of green buildings can test, measure and guide all the steps of building design, construction and maintenance and largely meet the criteria of resource-saving and energy-saving. The results of this paper provide a reference for further research on the environmental benefit analysis of green buildings based on BIM technology.
Aging Hallmarks and Anti-aging Strategies: A Landscape of Research Advancement
Authors: Tenchov Rumiana , Sasso Janet , Wang Xinmei , Zhou Qiongqiong Angela
Published: July 2023

Aging is a dynamic, time-dependent process characterized by a gradual accumulation of cell damage. Continual functional decline in the intrinsic ability of living organisms to accurately regulate homeostasis leads to increased susceptibility and vulnerability to diseases. Anti-aging research has a long history throughout civilization, with many efforts put forth to understand and prevent the effects of aging. Thus, the major cellular and molecular hallmarks of aging have been identified and multiple strategies aiming to promoting healthy aging and extending the lifespan including lifestyle adjustments, medical treatments, and social programs, have been developed. Here, we use data from the CAS Content Collection to analyze the publication landscape of recent research. We review the advances in knowledge and delineate trends in research advancement on aging factors and attributes, as well as the anti-aging strategies across time, geography, and development pipelines. We also review the current concepts related to the major aging hallmarks on the molecular, cellular, and organismic level, the age-associated diseases, with attention to brain aging and brain health support, as well as the major biochemical processes associated with aging. We further assess the state-of-the-art anti-aging strategies and explore their correlations with age-related diseases. Well-recognized and novel, currently evaluated anti-aging agents have been summarized. Finally, we review clinical applications of anti-aging products with their development pipelines. We hope this review will be helpful for apprehending the current knowledge in the field of aging progression and prevention, in effort to further solve the remaining challenges and fulfil its potential.