bluuebunny/crossref_metadata_2025 huggingface dataset:
The Nature of Immune Responses to Influenza Vaccination in High-Risk Populations
Authors: Wiggins Kristin B. , Smith Maria A. , Schultz-Cherry Stacey
Published: June 2021

The current pandemic has brought a renewed appreciation for the critical importance of vaccines for the promotion of both individual and public health. Influenza vaccines have been our primary tool for infection control to prevent seasonal epidemics and pandemics such as the 2009 H1N1 influenza A virus pandemic. Certain high-risk populations, including the elderly, people with obesity, and individuals with comorbidities such as type 2 diabetes mellitus, are more susceptible to increased disease severity and decreased vaccine efficacy. High-risk populations have unique microenvironments and immune responses that contribute to increased vulnerability for influenza infections. This review focuses on these differences as we investigate the variations in immune responses to influenza vaccination. In order to develop better influenza vaccines, it is critical to understand how to improve responses in our ever-growing high-risk populations.
Robert Braidwood (Bob) Sim. 1951–2021: A Disciple’s Perspective
Authors: Díaz Álvaro
Published: June 2021

Three and a half months ago, we were very much saddened by the news of Bob Sim’s passing away [...]
Paleoenvironmental Evolution and Sea Level Change in Saronikos Gulf (Aegean Sea, Greece): Evidence from the Piraeus Coastal Plain and Elefsis Bay Sedimentary Records
Authors: Triantaphyllou Maria V. , Tsourou Theodora , Kouli Katerina , Koukousioura Olga , Dimiza Margarita D. , Aidona Elina V. , Syrides George , Antoniou Varvara , Panagiotopoulos Ioannis P. , Vandarakis Dimitris , Pallikarakis Aggelos , Cheilaris Sofia , Skampa Elisavet , Goiran Jean-Philippe , Fouache Eric , Pavlopoulos Kosmas P.
Published: June 2021

Thorough faunal (benthic foraminifera, ostracods, molluscs) and palynomorph analyses as well as magnetic susceptibility measurements performed on the Piraeus coastal plain sedimentary sequences have shed light on the paleoenvironmental evolution of the area since ca. 9000 cal BP. Benthic and palynomorph assemblages along with magnetic susceptibility suggest a typical lagoonal environment with significant freshwater inputs at the eastern part of the plain after 8700 cal BP. Between 7500 and 5400 cal BP, microfaunal assemblages, mollusc fauna and magnetic susceptibility suggest a shallow marine paleoenvironment, with Piraeus forming a tied island in the center of the bay. Since ca. 4800 cal BP a closed oligohaline lagoon is evidenced in the western part of the Piraeus plain further developed to a marsh after 2800 cal BP, while a coastal environment associated with the fluvio-deltaic system of Kifissos and Korydallos Rivers is continually developing to the west. Signs of cultivation and grazing activities in the area are evidenced since the Early Bronze Age, culminating during the Classical Period. A comparison with a well-dated marine record, recovered from the nearby shallow Elefsis Bay, provides a reasonable estimation of ~5 mm/yr for the absolute sea level rise rate in the inner Saronikos Gulf during the Mid-Holocene.
Conversion of Whey into Value-Added Products through Fermentation and Membrane Fractionation
Authors: Caballero Alejandro , Caballero Pablo , León Federico , Rodríguez-Morgado Bruno , Martín Luis , Parrado Juan , Vaswani Jenifer , Ramos-Martín Alejandro
Published: June 2021

The cheese whey (95% composed of water) is an effluent produced in the cheese industry, of which more than 1.5 million tons are generated in Spain, constituting a serious environmental problem. The process starts with a new fermentative/enzymatic technology that totally converts whey, mainly composed by lactose, proteins, and salts, into a fermented product with higher added value. This new product is mainly composed by lactic acid bacteria biomass, ammonium lactate, and a protein hydrolysate. To separate valuable fractions, this fermented product is processed by a two-stage membrane system, which is a very innovative process in this type of fermented product. The first stage consists of ultrafiltration to separate all suspended solids. As a result of this stage, a product mainly constituted by lactic acid bacteria that have both agronomic applications, mainly as a biocontrol and biofertilizer/bio-stimulant, and applications in animal feeding as a probiotic, is obtained. The second stage consists of reverse osmosis used to concentrate the ultrafiltered permeate obtained earlier, leading to a microbiologically stable product and reducing transport costs. The concentrate is mainly composed of ammonium lactate and a protein hydrolysate, constituted by peptides and free amino acids, which has application both in agriculture as a bio-stimulant and in animal feeding, and the permeate is water, reusable in other industrial processes. This work demonstrates the technical feasibility of this valorization process to achieve the objective of “Waste 0” from a problematic by-product, while obtaining products with commercial utility.
A New Evolutionary Approach to Optimal Sensor Placement in Water Distribution Networks
Authors: Ponti Andrea , Candelieri Antonio , Archetti Francesco
Published: June 2021

The sensor placement problem is modeled as a multi-objective optimization problem with Boolean decision variables. A new multi objective evolutionary algorithm (MOEA) is proposed for approximating and analyzing the set of Pareto optimal solutions. The evaluation of the objective functions requires the execution of a hydraulic simulation model of the network. To organize the simulation results a data structure is proposed which enables the dynamic representation of a sensor placement and its fitness as a heatmap. This allows the definition of information spaces, in which the fitness of a placement can be represented as a matrix or, in probabilistic terms as a histogram. The key element in the new algorithm is this probabilistic representation which is embedded in a space endowed with a metric based on a specific notion of distance. Among several distances between probability distributions the Wasserstein (WST) distance has been selected: WST has enabled to derive new genetic operators, indicators of the quality of the Pareto set and criteria to choose among the Pareto solutions. The new algorithm has been tested on a benchmark water distribution network with two objective functions showing an improvement over NSGA-II, in particular for low generation counts, making it a good candidate for expensive black-box multi-objective optimization
CFD Modeling of a Stirred Anaerobic Digestion Tank for Evaluating Energy Consumption through Mixing
Authors: Dabiri Soroush , Noorpoor Alireza , Arfaee Maziar , Kumar Prashant , Rauch Wolfgang
Published: June 2021

The anaerobic digestion process is an effective means to eliminate the detrimental impacts of cattle manure discharge into the environment, i.e., biochemical contamination and substantial methane emissions, the latter leading to global warming. For proper operation of anaerobic digesters, an efficient mixing provides a relatively homogenous mixture of the feedstock within the tank. This study aims to investigate the mixing process and the total energy consumption needed for stirring by using an asymmetrical mixer. A further objective is to analyze the formation of stagnant volume and the velocity gradient in the digester in order to assure the mixing efficiency of the mixer type. The computational model is implemented as the finite volume method, and the rheological properties of the feedstock are considered. The results are validated by comparing the on-site power consumption of the mixer with the values obtained by the numerical torque. At various mixer speeds, the dead volume does not exceed 0.5% of the digester tank; however, with the increase of the mixer rotation speed, the energy consumption of the mixer increases drastically.
Introduction of a handmade vacuum-assisted sponge drain for the treatment of anastomotic leakage after low anterior rectal resection
Authors: Keshvari Amir , Badripour Abolfazl , Keramati Mohammad Reza , Kazemeini Alireza , Behboudi Behnam , Fazeli Mohammad Sadegh , Rahimpour Ehsan , Ghaffari Parisa , Tafti Seyed Mohsen Ahmadi
Published: June 2021

Purpose: Anastomotic leakage, a known major postoperative complication, potentially leads to readmission, reoperation, and increased mortality rates in patients, such as rectal cancer patients following a low anterior resection (LAR). Currently, vacuum-assisted closure, as featured by B-Braun (B-Braun Medical B.V.), is already being used for the treatment of gastrointestinal leakages and fistulas. The main aim of this study was to introduce a novel method for creating a vacuum-assisted drain for the treatment of anastomotic leakage after LAR.Methods: All 10 patients, who underwent LAR surgery from 2018 to 2019, were diagnosed with anastomotic leakage and had received neoadjuvant chemotherapy prior to surgery. Therefore, patients were treated with a handmade vacuum-assisted drain and were revisited every 5 to 7 days for further evaluations and drain replacement until leakage resolution. Physical features of cavity, time of diagnose, and duration of treatment were analyzed correspondingly. The handmade vacuum-assisted sponge drain was prepared for each patient in each session of follow-up.Results: Eight out of 10 patients experienced complete closure of the defect. The mean delay time from the day of operation to the diagnosis of anastomotic leakage was 61.0±80.4 days while the mean time for leakage closure was 117.6±68.3 days. Eventually, 7 cases underwent ileostomy reversal with no complications during a 3-month follow-up.Conclusion: In this study, we evaluated the healing process of anastomotic leakage after the usage of a handmade vacuum-assisted sponge drain in a case series method. In our trial, we provided an innovative cost-benefit method easily applicable in the operating room.
Book Review of Roots of Yoga (Mallinson and Singleton, 2017).
Authors:   Brown University, Gerety Finnian
Published: June 2021

Roots of Yoga. Translated and edited with an introduction by James Mallinson and Mark Singleton. London: Penguin Books, 2017. Paperback. xl + 540 pages
Late 19th Century Jātaka Murals at the Buddhist Monastery in Batuvantudava, Sri Lanka
Authors: Koch Rolf Heinrich
Published: June 2021

Cet article présente un ensemble de peintures murales du XIXe siècle parant au Sri Lanka le temple (« maison de l’image ») du monastère bouddhique de Batuvantudava, soit un sanctuaire principal où trône un Buddha assis et deux sanctuaires dédiés aux dieux bouddhistes. Les murs intérieurs du temple sont ornés de sept des histoires des vies antérieures (Jātaka) du Buddha Gautama. La présentation de ces peintures murales, ici explicitées à l’aune des sources singhalaises, constitue le cœur de cet article.
ANÁLISE SOBRE A SAÚDE MENTAL DOS PROFISSIONAIS DE ENFERMAGEM NO ENFRENTAMENTO DA COVID-19: UMA ANÁLISE NUM HOSPITAL REGIONAL
Authors: Rosa Thiago José Lima , Nascimento Samara Martins , de Sousa Reudismam Rolim , Oliveira Danielle Martins do Nascimento
Published: June 2021

Percebeu-se uma lacuna a respeito da real situação da saúde mental de profissionais de enfermagem e se o nível de estresse atual (após receberem os imunizantes) é equivalente ao anterior à aplicação do mesmo, que tem como propósito imunizar os profissionais. Com isso, este trabalho visa compreender a mudança no estado da saúde mental dos enfermeiros após a vacinação e para isso foi escolhido o Hospital Universitário da Paraíba para a aplicação do questionário. Este trabalho tem caráter quali-quantitativo, pois busca investigar as dificuldades vividas pelos enfermeiros que trabalham na linha de frente no combate à pandemia. Após a análise das informações foi percebido que os profissionais inquiridos, em maioria, possuem conhecimento técnico para atuarem no enfrentamento da pandemia e, mesmo possuindo esse conhecimento técnico, passaram por treinamentos que tinham como objetivo garantir a segurança de todos os envolvidos, desde o atendimento inicial aos pacientes infectados pela COVID-19 até sua saída do hospital. Foi constatado que houve um considerável aumento na quantidade de trabalho e no nível de estresse desses profissionais, bem como sofrimentos externos ao ambiente de trabalho, o que pode explicar a procura destes profissionais por atendimentos psicológicos. Conclui-se, por meio dessa pesquisa exploratória, que estes profissionais necessitam de um maior acolhimento por parte da sociedade e espera-se que haja a criação de políticas públicas que visem auxiliá-los com atendimentos psicológicos, para que possam exercer suas atividades da maneira mais segura e eficiente, mediante o cenário vivenciado.
Factors controlling longshore variations of beach changes induced by Tropical Storm Eta (2020) along Pinellas County beaches, west-central Florida
Authors: Cheng Jun , Toledo Cossu Francesca , Wang Ping
Published: June 2021

Tropical Storm Eta impacted the coast of west-central Florida from 11 November to 12 November 2020 and generated high waves over elevated water levels for over 20 hours. A total of 148 beach and nearshore profiles, spaced about 300 m (984 ft) apart, were surveyed one to two weeks before and one to eight days after the storm to examine the beach changes along four barrier islands, including Sand Key, Treasure Island, Long Key, and Mullet Key. The high storm waves superimposed on elevated water level reached the toe of dunes or seawalls and caused dune erosion and overwash at various places. Throughout most of the coast, the dune, dry beach, and nearshore area was eroded and most of the sediment was deposited on the seaward slope of the nearshore bar, resulting in a roughly conserved sand volume above closure depth. The longshore variation of beach-profile volume loss demonstrates an overall southward decreasing trend, mainly due to a southward decreasing nearshore wave height as controlled by offshore bathymetry and shoreline configurations. The Storm Erosion Index (SEI) developed by Miller and Livermont (2008) captured the longshore variation of beach-profile volume loss reasonably well. The longshore variation of breaking wave height is the dominant factor controlling the longshore changes of SEI and beach erosion. Temporal variation of water level also played a significant role, while beach berm elevation was a minor factor. Although wider beaches tended to experience more volume loss from TS Eta due to the availability of sediment, they were effective in protecting the back beach and dune area from erosion. On the other hand, smaller profile-volume loss from narrow beach did not necessarily relate to less dune/ structure damage. The opposite is often true. Accurate evaluation of a storm’s severity in terms of erosion potential would benefit beach management especially under the circumstance of increasing storm activities due to climate change.
Efectos de un accidente ferroviario sobre la demanda del servicio: El caso de la tragedia de Once en Argentina
Authors:   , Italia Matías Agustín
Published: June 2021

Este trabajo evalúa el impacto de un accidente ferroviario, conocido como la “Tragedia de Once”, sobre la demanda de viajes del servicio afectado en Argentina. Debido a que el accidente no puede considerarse como un shock exógeno, para identificar el efecto causal de la tragedia se utiliza la metodología de Control Sintético. Específicamente se considera una combinación de diferentes ramales para construir un control sintético que simule en características relevantes el ramal afectado, antes de que sucediera el accidente. Los resultados indican que para los dos años posteriores al accidente la evolución de los boletos vendidos por tren corrido es en promedio entre 53pp y 59pp menor que el control sintético. El efecto identificado comienza a reducirse a partir de 19 meses luego del accidente, hasta desaparecer luego de 28 meses. Además, debido a que el ramal afectado pudo haber sufrido una reducción en el pago del boleto, al utilizar como grupo de control ramales más comparables en términos de evasión, se encuentra que el efecto se reduce a -21pp. Este trabajo se destaca por su aporte original a la literatura, ya que a la fecha no se han encontrado antecedentes sobre evaluaciones de impacto vinculadas a accidentes ferroviarios en Argentina.
Artificial Impacts upon Water Bodies
Authors:   Lepikhin A.P.
Published: June 2021

Some aspects of the history of waste water disposal systems regulation and setting of criteria of maximal permissible impact upon water bodies have been discussed. Approaches based on three various concepts, i.e. environmental, consumptive, and technological are the most wide spread both in this country and abroad. We have shown that the crisis of the currently active regulation system in this country is mostly connected with the lack of attention to the special features of the concrete water bodies natural hydro/chemical regime in the process of the double genesis substances disposal regulation.
Religious Education and the Delegitimation of Knowledge
Authors: Sajjadi Seyed Mahdi
Published: June 2021

The velocity of information production has increased at all levels, including the global. These expansions lead to the delegitimation of knowledge by equating information with knowledge or the predominance of information over knowledge. Given that this situation has caused epistemological challenges for the process of religious education, this article attempts to study the epistemological problems and challenges posed by information technology (IT) in this area.
SKRINING FITOKIMIA DAN PENETAPAN KADAR FENOL TOTAL PADA EKSTRAK DAUN NANGKA (Artocarpus heterophyllus), CEMPEDAK (Artocarpus integer), dan TARAP (Artocarpus odoratissimus) ASAL DESA PENGARON KABUPATEN BANJAR
Authors:   Prodi Farmasi FMIPA Universitas Lambung Mangkurat, Ikhwan Rizki Muhammad , Nurlely Nurlely , Fadlilaturrahmah Fadlilaturrahmah , Ma’shumah Ma’shumah
Published: June 2021

The leaves of jackfruit (Artocarpus heterophyllus), cempedak (Artocarpus integer), and tarap (Artocarpus odoratissimus) are used empirically by the people of Desa Pengaron, Banjar Regency for treat antimalarials, antidiabetic, abdominal pain, and cancer. The secondary metabolites of the phenol group are responsible for various plant activities. This study aims to determine of compounds and total phenol content in leaves of jackfruit (A. heterophyllus), cempedak (A. integer), and tarap (A. odoratissimus). The leaf samples were oven-dried, then the leaf powder was extracted using ethanol. Phytochemical screening was carried out on the extract using reagents, and phenol content was determined using a spectrophotometer UV-Vis. The results showed that the extracts of leaves jackfruit (A. heterophyllus), cempedak (A. integer), and tarap (A. odoratissimus) contained phenol, flavonoids, and tannins. Total phenol content of leaves A. heterophyllus, A. integer and A. odoratissimus were 13,174 ± 1,378 mgGAE / gram extract, 37,204 ± 2,202 mgGAE / gram extract, and 35,886 ± 0.890 mgGAE / gram extract.
Bench-scale Electrochemical Treatment of Co-contaminated Clayey Soil
Authors:   Washington State University, Pelletier Austin , Hohner Amanda ,   Washington State University, Deniz Akin Idil ,   Washington State University, Chowdhury Indranil ,   Washington State University, Watts Richard ,   Washington State University, Shi Xianming ,   Washington State University, Dutmer Brendan ,   Highland Community College, Mueller James ,   Provectus Environmental Products, Inc.
Published: June 2021

Industrial soil contamination is frequently unearthed by transportation agencies during construction within the right-of-way. As a result, transportation agencies may experience construction delays. Soils co-contaminated with high-molecular-weight polycyclic aromatic hydrocarbons (HMW-PAHs) and metals are commonly encountered in Illinois and exhibit recalcitrance towards conventional treatment technologies. This issue is exacerbated in the fine-grained soils common to Illinois, where low-permeability and immense sorption capacity increase treatment complexity, cost, and duration. Contaminated sites are spatially and temporally restrictive and require rapid in situ treatments, whereas conventional soil remediation requires 1 to 3 years on average. Consequently, transportation agencies typically pursue excavation and off-site disposal for expediency. However, this solution is expensive, so a comparatively expeditious and affordable treatment alternative is needed to combat the increasing cost of hazardous waste disposal. The objective of this work was to develop an accelerated in situ treatment approach adaptable for use at any construction site to cost-effectively remove HMW-PAHs and metals from clayey soil. It was hypothesized that an in situ electrochemical treatment which augments electrokinetics with H2O2 could remediate both HMW-PAHs and metals in less than a month. Bench-scale reactors resemblant of field-scale in situ electrokinetic systems were designed and fabricated to assess the electrochemical treatment of clayey soils contaminated with HMW-PAHs and metals. Pyrene, chromium, and manganese were used as model contaminants, spiked into kaolinite as a model clay. Electrokinetics were imposed by a low-intensity electrical field distributed by graphite rods. Electrolytic H2O2 systems were leveraged to distribute electrical current and facilitate contaminant removal. Average contaminant removals of 100%, 42.3%, and 4.5% were achieved for pyrene, manganese, and chromium, respectively. Successful development of this bench-scale treatment approach will serve to guide transportation agencies in field-scale implementation. The results from this work signify that electrochemical systems that leverage eco-friendly oxidant addition can replace excavation and disposal as a means of addressing clayey soils co-contaminated with HMW-PAHs and metals.
CORRELATION BETWEEN BODY FAT PERCENTAGE AND TOTAL CHOLESTEROL LEVELS TO HYPERTENSIVE ELDERLY WOMAN IN MADIUN
Authors: Widhi Binar Wahyuning , Putri Mega Arianti
Published: June 2021

Background: Patients with hypertension have twice as great exposed to heart disease and eight times as large as a stroke risk than who do not experience hypertension. Risk increase in blood pressure on the person who has overweight than people with normal weight. Women who have increased cholesterol levels in the blood more vulnerable for hypertension (Nikolov et al., 2015).
Objectives: The purpose of this research aimed to determine a percentage of body fat and cholesterol levels of the elderly women in Posyandu, Geger Subdistrict, Madiun who occurrence of hypertension.
Methods: This research using cross sectional design. The sample using purposive sampling technique with 38 respondent which satisfy the inclusion criteria. Instrument used is Bioelectrical Impedance Analysis tool. Statistical test used is spearman rho with a significance level of α < 0.05.
Results: The results of this study showed that significant relationship between body fat percentage and blood pressure (p-value = .033; r = .304). Meanwhile, total cholesterol level did not show any relationship with blood pressure (p-value = .429; r = -.132).
Conclusion: Fat Accumulation in the kidneys where the renin-angiotensin system is identified in human fat tissue, can cause impaired nephron function which causes blood pressure to rise. Thus, abdominal obesity accompanied by ectopic fat deposits can play an important role in the development of hypertension and should not be neglected when undertaking blood pressure-lowering therapy.
 
Keywords: Body fat, cholesterol, elderly women.
THE RELATIONSHIP OF PHYSICAL DISTANCING WITH MENTAL HEALTH OF INDONESIAN COMMUNITY DURING COVID-19
Authors: Yuniarti Enny Virda , Andriyanto Arief
Published: June 2021

Background: The spread of the COVID-19 virus has spread widely throughout the world, which affects various aspects (Lebov et al., 2017). Several aspects affected by the transmission of the COVID-19 virus are psychological / mental health impacts caused by the implementation of policies from various countries in the form of a physical distancing system (Ornell, Schuch, Sordi, & Kessler, 2020).
Objectives: Analyze the relationship between physical distancing and the mental health of Indonesian community during Covid-19.
Methods: The cross-sectional study design. The sample of the study was the Indonesian people affected by the covid-19 pandemic who were taken based on purposive sampling with complete answer criteria as many as 1,090 respondents. The research instrument consisted of 2 questionnaires, including: a method questionnaire in physical distancing practices methods consisting of 11 items of physical distancing application to prevent the spread of the Covid-19 virus as recommended by World Health Organization. The Self-Reporting Questionnaire-29 is a questionnaire issued by the Directorate of Mental Health Services of the Indonesian Ministry of Health with the domains of anxiety and depression, psychomatics, symptoms of psychotic disorders, trauma stress. Parametric statistical tests used the Pearson test (p-value < 0.05).
Results: The results obtained a p-value of 0.03, which means that there is a physical distancing relationship with the mental health of the Indonesian people during Covid-19.
Conclusion: There is a significant relationship between physical distancing and the mental health of the Indonesian people. Recommendations for health workers, especially nurses in providing health services to the community, must be more comprehensive and recognize client responses to prevent psychological impacts.
 
Keyword: Physical distancing; mental health; covid-19 pandemic.
RELATIONSHIP OF AGE AND NUTRITION STATUS WITH WORK FATIGUE IN INPATIENT NURSES AT DR M YUNUS HOSPITAL, BENGKULU
Authors: Rina Aprianti  , Wulan Susilo , Wulandari Elza
Published: June 2021

Background: Nurse is a profession that cannot be separated from the problem of work fatigue. Fatigue due to work will have a negative impact on work such as decreased accuracy, skill, and even work productivity. If this happens to nurses, it can put the patient at risk, decreasing the quality of service. Work fatigue is caused by several factors, such as worker characteristics, namely age, sex, education, nutritional status, and work environment factors (Tarwaka, 2013). Nurses have a fairly heavy duty in assisting emergency services and nursing services continuously for 24 hours so that nurses sometimes eat irregularly which can cause nutritional conditions to be disturbed (Astuti, Ekawati, & Wahyuni, 2017).

Objectives: The purpose of this study was to determine the relationship between age, nutritional status and subjective work fatigue in inpatient nurses at dr. M Yunus Bengkulu.

Methods: The research design was an analytic survey with a cross sectional approach. The population of this study were 128 nurses in the inpatient room with total sampling technique. The data collection instrument is a work fatigue feeling questionnaire consisting of 17 questions adopted from (Setyawati, 2010) which has tested the validity and reliability in her book entitled at a glance about work fatigue, a nutritional status questionnaire by taking physical measurements of body weight and height to determine BMI, and age questionnaire with units of years. Data analysis used chi square test with 95% degree of error if p-value ≤ 0.05 indicates a significant relationship and if > 0.05 is not significant.

Results: This study shows that there is no relationship between age and subjective work fatigue on nurses with a p-value = 0.107 > α = 0.05. And there is a relationship between nutritional status and subjective work fatigue on nurses with a p-value = 0.000 > α = 0.05.

Conclusion: Work fatigue that occurs in nurses is expected to be an important concern, nurses should maintain a healthy body by consuming balanced nutritious food and diligent exercise and adequate rest, so as to reduce the risk of fatigue due to work.

 

Keywords: Age, Nutrition Status, Work Fatigue.
ВЕТЕРИНАРНО-САНІТАРНА ОЦІНКА ЯКОСТІ І БЕЗПЕЧНОСТІ РИБИ ПІВДЕННОГО РЕГІОНУ УКРАЇНИ (ОГЛЯДОВА СТАТТЯ)
Authors: Коваль О. , Голубенко О. , Рудь В. , Тарасенко Л.
Published: June 2021

В огляді узагальнені дані про захворювання коропу, які зустрічаються у Хаджибейському лимані. У останні роки спостерігається збільшення поширення захворюваності коропових риб і збитки рибництву та іхтіофауні регіону. На основі інформації щодо розповсюдженості захворювань серед коропу у Південному регіоні України, був проведений загальний огляд найбільш поширених хвороб коропу. Серед незаразних захворювань найбільшу увагу потрібно приділити аліментарним хворобам, токсикозам, порушенням режиму водойм. Інфекційні хвороби коропа представлені некрозом зябер, краснухою, бронхіомікозом та сапролегніозом. Зустрічаються паразитичні хвороби, які представлені іхтіофтіріозом та аргульозом, та захворювання викликані інфузоріями, триходініоз. У Хаджибейському лимані спостерігається масова загибель риби від перевищення допустимого вмісту сірководню. Для забезпечення високої якості харчової сировини і запобігти розповсюдженості захворювань та загибелі риби, потрібно проводити іхтіологічний контроль, ветеринарно-санітарну експертизу та санітарну оцінку якості риби.
ЗМІНА ФАЗОВОГО СТАНУ СУМІШІ КОМБІКОРМІВ ДЛЯ ТВАРИН І ПТАХІВ
Authors: Уминський С. , Дударев І. , Яковенко А. , Чучуй В. , Королькова М. , Дмитрієва С.
Published: June 2021

У разі якщо виробничим циклом визначено час недостатнє для досягнення однорідної суміші, то це призводить до зміни рецептурного складу, що є неприпустимим при годуванні тварин. Оптимальний час змішування як правило визначається емпіричними даними на основі моніторингу суміші і тестування. Розмах рекомендованого часу змішування різними типами змішувачів на сьогоднішній день має значні величини і може істотно відрізняться. Для досягнення найкращих показників по досягненню однорідності кормової суміші для тварин часто збільшують час перебування компонентів в робочій зоні машини, що в свою чергу призводить до негативних наслідків, внаслідок виникає сегрегації, і погіршення показників однорідності. З іншого боку необґрунтоване скорочення часу на освіту однорідної суміші також є проблемою при виникненні якої відбувається зміна рецептурного складу. Тому визначення обґрунтованого часу змішування інгредієнтів при виготовленні комбікорму є актуальним завданням сучасного виробництва.
Malformation in the crab Ucides cordatus (Linnaeus, 1763) (Crustacea, Brachyura, Ocypodidae), in São Vicente (SP), Brazil.
Authors: Pinheiro Marcelo Antônio Amaro , Toledo Tomas Roman de
Published: June 2021

In the seventies, the region known as Baixada Santista was a large repository of environmental contamination mainly resulting from industrial waste. In effect, the contaminated residues came from different toxic substances including chemical, biochemical and others. Industrial waste was dumped or even stored in inadequate fragile ecological sites without any previous treatment and it resulted in significant amounts of air, soil and water pollution. A male specimen of U. cordatus presenting a malformation of the pollex (immovable finger) of its major claw (left) was captured in São Vicente city, raising concern to the local press and community. The immovable finger of the propodus segment in the claw of this specimen was modified into a structure in the form of a talon. This structure resembling an avian claw was comprised of five fixed ends united at the base. This might be a result from an injury of the original corpus structure while in a confrontation with another specimen. The newly found sample showed a high incidence of micronucleated cells in the haemolymph, approximately three times higher than normally reported. Perhaps this suggests the effect of an environmental influence in the morphology of the organism, most likely linked to the several sources of pollution in the region (public dump of Alemoa/Sambaiatuba, and the industrial conglomerate of Cubatão). We propose that similar measurements could be used in the estuarine area to assess and evaluate ecological risks and adverse biological effects.
Comportamento da produção total e por estado, frota permissionada e balança comercial de sardinha-verdadeira.
Authors: Dias-Neto Jose Dias , Oliveira de Geovânio Milton , Santos Geraldo Clelio Batista dos
Published: June 2021

A partir de 2001 ocorreu uma nova, lenta, mas continuada, recuperação da produção de sardinha-verdadeira (Sardinella brasiliensis), atingindo 83.920 t, em 2009. A queda de produção em 2010, da ordem de 30,59 %, em relação a 2009, indica a possibilidade de um novo ciclo de declínio, que pode levar a mais um grande colapso na pescaria de sardinha-verdadeira, se medidas urgentes não forem tomadas por parte dos gestores. A grande dinâmica de barcos permissionados, de ano para ano, pode apontar para um descontrole no sistema de Registro Geral da Pesca (RGP) ou, até, irregularidades no processo de renovação de permissões de pesca, ou fornecimento de novas permissões, quando o esforço de pesca dessa frota é limitado há mais de três décadas, levando a que se recomende avaliação rigorosa por parte das autoridades competentes. Agrava esse quadro a recomendação, ainda em 2006 (CERGOLE; DIAS-NETO, no prelo), para que o esforço de pesca total fosse reduzido para 80 barcos-padrão em vista do elevado nível de esforço de pesca observado. A balança comercial, a exceção de 1997, sempre foi negativa, ocorrendo, entretanto, variação anual das importações brasileiras, dominando o quadro de maiores quantidades quando as produções nacionais foram baixas. Ocorreu, ainda, tanto nas exportações quanto nas importações, significativo incremento nos preços (em dólar) por quilo de sardinha comercializada nos últimos anos.
Hubungan Self Care Management Dengan Kualitas Hidup Pasien Congestive Heart Failure
Authors: Destiawan Eko Utomo  , Febi Ratnasari  , Arfan Andrian
Published: June 2021

Latar belakang: Jumlah kematian penderita Congesive Heart Failure akan meningkat seiring dengan bertambahnya usia pasien tersebut, dengan jumlah kematian terbanyak terjadi pada pasien laki-laki dibandingkan dengan penderita CHF pada pasien wanita. Tujuan penelitian ini adalah untuk mengetahui hubungan self care management dengan kualitas hidup pasien congestive heart failure di RSUD Pesanggrahan Jakarta Selatan. Metode yang digunakan dalam penelitian ini adalah penelitian survey yang bersifat deskriptif dan desain Cross Sectional. Jumlah sampel sebanyak 101 orang responden. Hasil analisis tabulasi silang, menunjukan bahwa sebagian besar Self Care Management pada pasien congestive heart failure tergolong sudah baik dan kualitas hidup juga sudah baik. Hasil uji statistik diperoleh nilai p = 0,017, sehingga dapat disimpulkan ada hubungan self care management dengan kualitas hidup pasien congestive heart failure di RSUD Pesanggrahan Jakarta Selatan. Kesimpulan dari hasil penelitian ini diharapkan perawat dapat melaksanakan peran sebagai edukator saat di poliklinik, serhingga dapat meningkatkan pengetahuan pasien mengenai self care, motivasi, dan kualitas hidup pasien yang terdiagnosis gagal jantung.
ENTROPİ VE MAİRCA YÖNTEMİYLE TÜRK KATILIM BANKALARININ FİNANSAL PERFORMANS SIRALAMASI
Authors: BEKTAŞ Selahattin
Published: June 2021

İslami bankacılık olarak ifade edilebilen katılım bankacılığı, faizsiz bankacılık olarak da bilinmektedir. Katılım bankacılığı sektörü ilk olarak1980'li yıllarda ortaya çıkmıştır. Katılım bankacılığı sektörü, Türk bankacılık sektörünün tamamlayıcısıdır. Bundan dolayı bu sektörün performans analizinin ölçülmesi daha da önemli hale gelmiştir. Geleneksel bankacılık sisteminden farkı ise faaliyette bulunduğu bankacılık işlemlerini faizsizlik prensibine dayandırarak yapmasıdır. Türk bankacılık sisteminde tamamlayıcı bir unsur olan katılım bankacılığı sektörü devletin desteğiyle hızlı bir gelişim göstermiştir. Bu çalışmanın amacı, Türk bankacılık sistemi içinde faaliyette bulunan katılım bankalarının 2018-2019 yılları için finansal performanslarını ölçme ve sıralamaktır. Bundan dolayı Türk bankacılık sektöründeki altı katılım bankası analize dahil edilmiştir. Bu çalışmada katılım bankalarının finansal performanslarını ölçmek için Entropi ve Mairca yöntemi ortak kullanılmıştır. Katılım bankalarının finansal performans ölçümünde kullanılması için altı kriter belirlenmiştir. Bu kriterler, Toplam Aktifler, Toplam Krediler ve Alacaklar, Toplam Mevduatlar, Toplam Öz kaynaklar, Şube Sayısı ve Çalışan Sayıları olarak belirlenmiştir. Yapılan analiz sonucuna göre 2018 yılında en iyi performansı gösteren banka Ziraat Katılım Bankasıdır. İkinci en iyi performansı gösteren banka Türkiye Finans Katılım Bankasıdır. Üçüncü en iyi performansı gösteren bankada Kuveyt Türk Katılım bankasıdır. 2019 yılında ise en iyi finansal performansa sahip ilk üç banka sırasıyla, Kuveyt Türk Katılım Bankası, ikinci en iyi Ziraat Katılım Bankası, üçüncü en iyi finansal performansı ise Vakıf Katılım Bankası göstermiştir.
THE EFFECT OF TAXES ON DEMOCRACY: THE CASE OF OECD COUNTRIES
Authors: TABAR Çağlayan , KARAŞ Göksel
Published: June 2021

The aim of this study is to investigate the effect of taxes on democracy. In the study, 37 OECD countries were taken as a sample and the data between 2010-2019 were used annually. The study was conducted using panel regression method. In the study where two different models were created, the effect of both tax burden and tax structure on democracy was investigated. According to the results, the effect of tax burden on democracy was found to be statistically significant and positive. In terms of tax sutructures, while the effect of indirect taxes on democracy was found to be statistically significant and negative, the effect of direct taxes on democracy was found to be significant and positive.
A Panel of Tumor Biomarkers to Predict Complete Pathological Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer
Authors: Dalle Fratte Chiara , Mezzalira Silvia , Polesel Jerry , De Mattia Elena , Palumbo Antonio , Buonadonna Angela , Palazzari Elisa , De Paoli Antonino , Belluco Claudio , Canzonieri Vincenzo , Toffoli Giuseppe , Cecchin Erika
Published: June 2021

Pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients is related to a favorable prognosis. The identification of early biomarkers predictive of pathological complete response would help optimize the multimodality management of
the patients. A panel of 11 tumor-related proteins was investigated by immunohistochemistry in the pretreatment biopsy of a group of locally advanced rectal cancer patients to identify early biomarkers of pathological complete response to neoadjuvant chemoradiotherapy. A mono-institutional
retrospective cohort of 95 stage II/III locally advanced rectal cancer patients treated with neoadjuvant chemoradiotherapy and surgery was selected based on clinicalpathological characteristics and the availability of a pretreatment tumor biopsy. Eleven selected protein marker expression (MLH1,
GLUT1, Ki67, CA-IX, CXCR4, COX2, CXCL12, HIF1, VEGF, CD44, and RAD51) was investigated. The optimal cutoff values were calculated by receiver operating characteristic curve analysis. Classification and regression tree analysis was performed to investigate the biomarker interaction. Patients
presenting either Ki-67 or HIF1 or RAD51 below the cutoff value, or CXCR4 or COX2 above the cutoff value, were more likely to get a pathological complete response. Classification and regression tree analysis identified three groups of patients resulting from the combination of Ki-67 and CXCR4
expression. Patients with high expression of Ki-67 had the lowest chance to get a pathological complete response (18%), as compared to patients with low expression of both Ki-67 and CXCR4 (29%), and patients with low Ki-67 and high CXCR4 expression (70%). Pretreatment Ki-67, CXCR4, COX2, HIF1,
and RAD51 in tumor biopsies are associated with pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer. A combined evaluation of Ki-67 and CXCR4 would increase their predictive potential. If validated, their optimal cutoff could be used to select
patients for a tailored multimodality treatment.
Silymarin Regulates Tgf-β1/Smad3 Signaling Pathway and Improves Renal Tubular Interstitial Fibrosis Caused by Obstructive Nephropathy
Authors: Wu Jinhao , Huang Chao , Kan Gang , Xiao Hanyu , Zhang Xiaoping , Yang Jun
Published: June 2021

Obstructive nephropathy often leads to renal tubulointerstitial fibrosis. Understanding of the pathogenesis of renal tubulointerstitial fibrosis caused by obstructive nephropathy is crucial to the development of effective therapeutic drugs to improve the prognosis of the patients. Silymarin, a polyphenolic flavonoid extracted from plants, has been shown to exhibit antiinflammatory and antioxidant effects ameliorating liver and kidney damage. However, the effect of silymarin on renal fibrosis in obstructive nephropathy remains to be explored. In this study, we found silymarin improved interstitial fibrosis and apoptosis induced by TGF-β1 and ameliorated oxidative damage. Our data further confirmed that silymarin regulates the TGF-β1/ Smad3 signaling pathway, and therefore improves renal tubular interstitial fibrosis caused by obstructive nephropathy.
FORMATION OF A POSITIVE IMAGE OF A PRESCHOOL EDUCATIONAL ORGANIZATION
Authors:   Altai State Pedagogical University, Gordeeva L. N. , Kholodkova O. G. ,   Altai State Pedagogical University
Published: June 2021

The article provides a comparative analysis of the terms “image” and “reputation”. A brief description of the implementation of the dynamic model of managing the process of forming a positive image of a preschool educational organization and its main components is presented. The results of the implementation of this model are presented on the basis of a survey of the target audience - a group of pupils’ parents. The article shows the approbation of the components of the proposed image model within the framework of the regional educational and methodological association of preschool education managers.
FORMATION OF DIGITAL CULTURE OF MILITARY UNIVERSITY STUDENTS
Authors:   Branch of the Military Educational and Scientific Centre of the Air Force N.E. Zhukovsky and Y.A. Gagarin Air Force Academy, Raetskaya O. V.
Published: June 2021

The article considers the problem of introducing new digital technologies which is relevant for the Armed Forces of Russia. Military university students are required to receive training in working with high-tech equipment, monitoring the work of computerized military equipment, and comply with regulations for the professional information protection. The training of competent military professionals requires the synthesis of theoretical and practical training implemented through digital technologies. Components of students’ digital proficiency and approaches to their formation are considered. The results of surveys of digital proficiency formation among students and teachers of a military educational institution are presented. The hypothesis is confirmed that the introduction of FSES 3++ will provide for the training of competent military professionals with digital proficiency.
ANALYSIS OF THE TRANSFORMATION OF ADDITIONAL VOCATIONAL EDUCATION SYSTEM AT A PEDAGOGICAL UNIVERSITY
Authors:   Altai State Pedagogical University, Veretennikova L. A.
Published: June 2021

The article performs a retrospective analysis of the development of the system of additional vocational educational at a pedagogical university. Key management principles have been formulated that allow the structure to develop effectively in a changing organizational context. High-quality stages of development of the system of additional vocational education with analysis of their specifics are identified.
THE USE OF PRISONER LABOR IN THE ECONOMY OF ALTAI KRAI (1953-1965)
Authors:   Barnaul Law Institute of the Ministry of Internal Affairs of Russia, Manuilov E. V.
Published: June 2021

With the help of forced labor of those convicted of crimes, the development of sparsely populated areas (including Altai Krai) took place, both in our country and abroad. Severe sanitary conditions and low motivation reduced the prisoners’ productivity. In Soviet times, since the beginning of industrialization and mass repression, the special contingent was actively used as a labor force. After the change of power in the USSR, since 1953, repressive measures against its citizens have been reduced. In turn, the number of convicts decreases, as well as the number of correctional labor institutions, but the practice of using prisoners’ labor in the economy of Altai Krai persisted. People who were in the places of detention worked at various enterprises, making their contribution to the growth of material well-being, both in the region and in the country as a whole.
Effect of Ginger Tea on Chemotherapy-Induced Nausea and Vomiting among Patients Attending the Oncology Teaching Hospital, Baghdad 2020
Authors: Kadhim Remal Adel , Ali Besmah Mohammed , Kadhim Maysaa Adel , Mohammed Samer Jassim
Published: June 2021

Background: Ginger has been widely used to relieve nausea and vomiting in several settings, one ofthem, patients receiving chemotherapy. This study was done to assess the effect of ginger in controlling thechemotherapy induced nausea and vomiting (CINV) among patients. Methods: An interventional (pre-post)study design was conducted in oncology teaching hospital in Baghdad for three months. Sixty participantswere randomly assigned into intervention group (30 participants received ginger tea (1.5 g/d) with routineantiemetic regimen for the first 5 days of the chemotherapy cycle) and control group (30 participants receivedonly routine antiemetic regimen). MASCC Antiemesis Tool (MAT) was used for assessment of CINV incancer patients before and after the use of ginger tea.Results: No significant difference was observed between the intervention and control groups in the acuteand delayed phases of CINV after intervention with ginger tea(p >0.05), but difference between the studygroups was found statistically significant (p <0.05)regarding the severity of nausea postchemotherapy.Conclusions: The addition of ginger tea to routine antiemetic regimen in patients receiving chemotherapyeffectively reduced the severity of nausea. However, there is no additional role for ginger in reducing theacute and delayed phases of CINV.
Effect of Zinc Supplementation on Insulin Resistance, Lipid Profile, BMI in Type II Diabetic Patients
Authors: Witwit Ghusoon T. , Ali Besmah M. , Alsaffar Yasameen , Ghazala Anmar D.
Published: June 2021

Background: Zinc is one of the most important essential trace metals in human nutrition and lifestyle withspecial role in diabetic patients mainly due to its involvement in insulin production, storage and secretion.-Objectives: to assess the effect of zinc supplementation on changing insulin resistance ,modifying lipidprofile and body mass index(BMI) in type II diabetics.-Design and Setting: A randomized controlled clinicaltrial.-Study participants: the study was carried on 50 type II diabetic patients, both gender and followed for6 weeks. the participants were randomly divided into intervention group who receives 50 mg/d elementalzinc and control group without zinc supplement.-Materials: S. zinc, fasting plasma glucose(FPG), fastingS. insulin, HbA1c, lipid profile, BMI were measured at the beginning(before supplementation and at the endof the 6 weeks duration.Results: After 6 weeks of zinc supplementation, serum zinc levels improved significantly (P=0.0001). Therewas no significant difference in BMI (P=0.092). Insulin resistance (IR), HbA1c were significantly decreased(change mean -0.75 P=0.004 and -0.72, P=0.001) respectively. HDL-C was significantly increased (changemean 3.56 mg/dl P=0.022). TG and TC were significantly decreased (change mean-10.92mg/dl P=0.001 and– 3.52mg/dl P=0.009) respectively. There was significant positive correlation between zinc intake and serumzinc level (R2=0.432).-Conclusion: Our study results revealed that supplementation of 50 mg zinc sulphateimproves insulin resistance and induces more healthy lipid profile, while it has no significant effect on BMIof type II diabetic patients after 6 weeks of supplementation.