bluuebunny/crossref_metadata_2025 huggingface dataset:
Growth Hormone With Aromatase Inhibitor May Improve Height in CYP11B1 Congenital Adrenal Hyperplasia
Authors: Hawton Katherine , Walton-Betancourth Sandra , Rumsby Gill , Raine Joseph , Dattani Mehul
Published: January 2017

With an estimated prevalence of 1 in 100 000 births, 11β-hydroxylase deficiency is the second most common form of congenital adrenal hyperplasia (CAH) and is caused by mutations in CYP11B1. Clinical features include virilization, early gonadotropin-independent precocious puberty, hypertension, and reduced stature. The current mainstay of management is with glucocorticoids to replace deficient steroids and to minimize adrenal sex hormone overproduction, thus preventing virilization and optimizing growth. We report a patient with CAH who had been suboptimally treated and presented to us at 6 years of age with precocious puberty, hypertension, tall stature, advanced bone age, and a predicted final height of 150 cm. Hormonal profiles and genetic analysis confirmed a diagnosis of 11β-hydroxylase deficiency. In addition to glucocorticoid replacement, the patient was commenced on growth hormone and a third-generation aromatase inhibitor, anastrozole, in an attempt to optimize his growth. After the initiation of this treatment, the patient’s growth rate improved significantly and bone age advancement slowed. The patient reached a final height of 177.5 cm (0.81 SD score), 11.5 cm above his mid-parental height. This patient is only the second reported case of the use of an aromatase inhibitor in combination with growth hormone to optimize height in 11β-hydroxylase-deficient CAH. This novel treatment proved to be highly efficacious, with no adverse effects. It may therefore provide a promising option to promote growth in exceptional circumstances in individuals with 11β-hydroxylase deficiency presenting late with advanced skeletal maturation and consequent short stature.
Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations
Authors: Cogen Jonathan D. , Oron Assaf P. , Gibson Ronald L. , Hoffman Lucas R. , Kronman Matthew P. , Ong Thida , Rosenfeld Margaret
Published: January 2017

BACKGROUND AND OBJECTIVES:

Pulmonary exacerbations lead to significant morbidity and mortality in patients with cystic fibrosis (CF). National consensus guidelines exist, but few studies report current practice in the treatment and monitoring of pulmonary exacerbations. The goal of this study was to characterize consistency and variability in the inpatient management of CF-related pulmonary exacerbations. We focused on the use of guideline-recommended maintenance therapies, antibiotic selection and treatment regimens, use of systemic corticosteroids, and frequency of lung function testing. We hypothesized that significant variability in these treatment practices exists nationally.

METHODS:

This trial was a retrospective cross-sectional study. It included patients with CF aged ≤18 years hospitalized for pulmonary exacerbations between July 1, 2010, and June 30, 2015, at hospitals within the US Pediatric Health Information System database that are also Cystic Fibrosis Foundation–accredited care centers. One exacerbation per patient was randomly selected over the 5-year study period.

RESULTS:

From 38 hospitals, 4827 individual pulmonary exacerbations were examined. Median length of stay was 10.0 days (interquartile range, 6–14.0 days). Significant variation was seen among centers in the use of hypertonic saline (11%–100%), azithromycin (5%–83%), and systemic corticosteroids (3%–61%) and in the frequency of lung function testing. Four different admission antibiotic regimens were used >10% of the time, and the most commonly used admission antibiotic regimen comprised 2 intravenous antibiotics with no additional oral or inhaled antibiotics (29%).

CONCLUSIONS:

Significant variation exists in the treatment and monitoring of pulmonary exacerbations across Pediatric Health Information System–participating, Cystic Fibrosis Foundation–accredited care centers. Results from this study can inform future research working toward standardized inpatient pulmonary exacerbation management to improve CF care for children and adolescents.
Structure and Mechanical Properties of Functionally-Graded Nanostructured Metalloceramic Coatings
Authors: Catledge Shane A. , Vohra Yogesh K. , Woodard Shanna , Venugopalan Ramakrishna
Published: January 2017

A functionally graded nanocrystalline metalloceramic coating on cobalt-chrome alloy was investigated using thin film x-ray diffraction (XRD), cross-sectional transmission electron microscopy (TEM), nanoindentation, and scratch adhesion testing. The gradual transition in bonding from metallic (Cr/CrTi) near the interface to predominantly covalent (CrTiN) near the surface provides a combination of high toughness and high surface hardness. XRD analysis of the (CrTiN) coating suggests a cubic sodium chloride type phase structure with lattice parameter a = 4.2169±0.0035 Å. The surface layer structure is described as a tertiary Ti-N-Cr disordered solid solution that is predominantly cubic TiN, but with some Cr atoms substituted for Ti. TEM shows a transition from equiaxed 20-40 nm-sized grains at the surface to larger, elongated columnar grains below the surface. Nanoindentation measurements of the coating result in a hardness of 27 GPa and Young's modulus of 320 GPa. In addition, the high plasticity of 55% observed for this coating represents an increase in toughness over other ceramic coatings having similar hardness. The unique, functionally graded, smooth nanocrystalline metalloceramic coating structure provides an opportunity to reduce wear and increase longevity of total hip joint replacements.
PENANGKAPAN IKAN KAKAP MERAH DENGAN PANCING RAWAI DASAR DI PERAIRAN KARIMUN JAWA
Authors: M. Rijal M. Rijal
Published: January 2017

Abstrak bisa dilihat di Lampiran
IKIDIALIZINIŲ PACIENTŲ MOKYMAS
Authors: Čergelytė Indrė , Grigutis Mantas , Januškevičius Tomas , Miglinas Marius , Rimševičius Laurynas
Published: January 2017

Reikšminiai žodžiai: lėtinė inkstų liga, hemodializė, peritoninė dializė, švietimas. Paskutinės stadijos lėtinė inkstų liga (LIL) yra unikali, nes pacientai gali pasirinkti gydymo būdą: hemodializę, peritoninę dializę arba inkstų transplantaciją. Švietimas, kai pacientai turi apsispręsti, kokį PIT būdą pasirinkti, turi privalumų. Šis procesas turėtų būti pradedamas kuo anksčiau. Pacientus mokančią komandą turėtų sudaryti nefrologas ir slaugytoja. Pageidautina, kad procese dalyvautų dietologas, psichologas, socialinis darbuotojas bei fizinės medicinos ir reabilitacijos (FMR) gydytojas. Reikalinga bent viena mokymosi sesija. Pacientai, sergantys LIL, turėtų laikytis ir tam tikro mitybos režimo. Ikidializinių pacientų mokymo tikslas – pagerinti gyvenimo kokybę ir supratimą apie reikalingą dietą.
INKSTŲ VEIKLOS RODIKLIŲ IR SKYDLIAUKĖS HORMONŲ RYŠYS
Authors: Petravičiūtė Modesta , Zabulienė Lina , Pauliukienė Birutė , Urbonienė Jurgita , Gudynaitė Miglė , Miglinas Marius
Published: January 2017

Reikšminiai žodžiai: skydliaukės hormonai, hipotireozė, inkstų pažeidimas. Lėtinė inkstų liga (LIL) tampa vis opesnė sveikatos problema, nes sparčiai daugėja ja sergančių asmenų. LIL susijusi su įvairiomis ligomis, tarp jų ir skydliaukės disfunkcija. Mažėjant glomerulų filtracijos greičiui (GFG), didėja hipotireozės rizika, subklinikinė hipertireozė yra retesnė. Atliktas tyrimas, kurio tikslas – nustatyti inkstų funkcijos rodiklių ir tireotropinio hormono (TTH) koncentracijos ryšius. Darbo metodika. Retrospektyvinė kreatinino ir TTH tyrimų, atliktų 2011–2015 m. VšĮ Antakalnio poliklinikoje, rezultatų analizė. Į tyrimą įtraukti 4 938 suaugę pacientai, kuriems buvo atlikti abu TTH ir kreatinino koncentracijos serume tyrimai. Inkstų funkcijai įvertinti GFG nustatytas pagal MDRD formulę. Statistinė duomenų analizė atlikta naudojant SPSS 20 programą. Darbo rezultatai. Vidutinė TTH koncentracija 2,48 ± 4,21 mIU/l, vidutinė kreatinino koncentracija 70,67 ± 18,94 μmol/l, vidutinis GFG 86,87 ± 22,16 ml/min/1,73 m2. 48,2 proc. pacientų nustatytas lengvas inkstų pažeidimas, 9,4 proc. – vidutinis, o 0,3 proc.– sunkus ir galutinės stadijos LIL. Pacientai, turintys gerą inkstų funkciją, buvo statistiškai reikšmingai jaunesni, jų TTH rodiklis buvo statistiškai reikšmingai mažesnis nei pacientų, turinčių lengvą, vidutinį ir sunkų inkstų pažeidimą. 17,7 proc. pacientų, kurių GFG buvo mažesnis nei 60 ml/min/1,73 m2, turėjo subklinikinę ar kliniškai išreikštą hipotireozę. Nustatyta statistiškai reikšminga TTH koncentracijos priklausomybė nuo GFG (B = -0,024 (PI -0,029–-0,019), p < 0,0001) ir TTH koncentracijos priklausomybė nuo kreatinino (B = 0,022 (PI 0,015–0,028), p < 0,0001) ir amžiaus (B = 0,014 (PI 0,007–0,020), p < 0,0001). Išvados. 17,7 proc. pacientų su vidutiniu ir sunkiu inkstų pažeidimu turi subklinikinę arba kliniškai išreikštą hipotireozę. Mažėjant GFG ir didėjant kreatinino koncentracijai kraujyje, skydliaukės funkcija statistiškai reikšmingai mažėja, TTH kiekis didėja.
INKSTŲ PAŽEIDIMO DAŽNIS SERGANT TUBEROZINĖS SKLEROZĖS
KOMPLEKSU
Authors: Repeikaitė Jolanta , Čerkauskienė Rimantė , Čerkauskaitė Agnė , Mačionienė Ernesta , Miglinas Marius
Published: January 2017

Reikšminiai žodžiai: tuberozinės sklerozės kompleksas, inksto pažeidimas.
Tikslas. Nustatyti su tuberozinės sklerozės kompleksu susijusį inkstų pažeidimo dažnį ir įvertinti klinikinį pasireiškimą.
Medžiaga ir metodai. Retrospektyviai išanalizuoti pacientų, kuriems kliniškai/genetiškai nustatytas tuberozinės sklerozės
kompleksas, duomenys (N = 34). Vertinta inkstų pažeidimo forma, dydis ir radiologinis inkstų tyrimo būdas. Statistinė
analizė atlikta statistikos programų paketu SPSS 19.0 („SPSS, Inc.“, Čikaga, Ilinojus, JAV).
Rezultatai. Ištirti 34 pacientai: 13 (38,2 proc.) suaugusiųjų, iš jų 9 (69,23 proc.) moterys ir 4 (30,77 proc.) vyrai, amžiaus
vidurkis 17,71 ± 13,29 metų, ir 21 (61,8%) vaikas, amžiaus vidurkis 8,57 ± 5,4 metų. Inkstų pažeidimas nustatytas 14 (41,17
proc.) pacientų – 6 (42,86 proc.) moterims ir 8 (57,14 proc.) vyrams. Inkstų echoskopija atlikta 22 pacientams, 9 (40,9 proc.)
nustatyti dariniai inkstuose, MBR arba KT atlikta 13 pacientų, pokyčių rasta 11 (84,6 proc.), iš jų 5 (22,7 proc.) atliekant inkstų
echoskopiją patologijos nebuvo matoma. Angiomiolipomos rastos 10 (29,4 proc.), cistos – 12 (35,3 proc.), kalcinatai – 4
(11,8 proc.) atvejais. Didesnės negu 3 cm angiomiolipomos buvo 4 (11,8 proc.), abipusės – 7 (20,6 proc.) tiriamiesiems. Vaikų
grupėje devyniems (42,8 proc.) nustatyta inkstų patologija, didesnės negu 3 cm arba abipusės angiomiolipomos rastos 4 (44,4
proc.) atvejais. Inkstų pažeidimas su arterine hipertenzija buvo 5 (14,7 proc.) pacientams. Dviem suaugusiesiems nustatyta
lėtinė inkstų liga, vienam iš jų 3 stadija, kitam – 5 stadija bei atlikta dešinė nefrektomija dėl cistų komplikacijų. TSC1 arba
TSC2 geno mutacija nustatyta 10 pacientų, nė vienos mutacijos nerasta 2 pacientams, likusiems tirta nebuvo.
Išvados. Inkstų pažeidimas sergant tuberozinės sklerozės kompleksu nustatytas beveik pusei tiriamųjų ir pasireiškė vaikams.
Augančios angiomiolipomos inkstuose, galinčios sukelti intensyvų kraujavimą į retroperitoninį tarpą, rastos pusei vaikų, todėl
būtinas periodinis inkstų tyrimas. Patikimesnis radiologinis inkstų pažeidimo nustatymo būdas yra MRT.
GEMCITABINO SUKELTA TROMBINĖ MIKROANGIOPATIJA: KLINIKINIS
ATVEJIS
Authors: Alavočiūtė Urtė , Mačionienė Ernesta , Besusparis Justinas , Miglinas Marius
Published: January 2017

Reikšminiai žodžiai: gemcitabinas, trombinė mikroangiopatija, ūminis inkstų pažeidimas.
Šiame straipsnyje aprašomas gemcitabino sukeltos trombinės mikroangiopatijos atvejis. 69 metų moteris atvyko į Vilniaus
universiteto Santariškių klinikas besiskųsdama bendru silpnumu, dusuliu, pykinimu, vėmimu, apetito stoka, pradingusiu
šlapinimusi. Pacientė buvo operuota dėl kasos adenokarcinomos ir gydyta adjuvantine chemoterapija gemcitabinu. Laboratoriniuose
tyrimuose – hemolizinė anemija, trombocitopenija, padidėjusi kreatinino koncentracija, hiperkalemija. Pradėtos
hemodializės. Imunogenetiniais tyrimais nustatytas ADAMTS13 nežymus aktyvumo sumažėjimas. Leukogramoje – šistocitai.
Atlikta inksto biopsija patvirtino trombinės mikroangiopatijos diagnozę. Po dviejų savaičių pradėtos plazmaferezės.
ĮGYTOS PATIRTIES ĮTAKA ŠLAPIMO NELAIKYMO KOREKCIJOS TRANSOBTURATORINIU RAIŠČIU REZULTATAMS
Authors: Jukna Povilas , Smelevičienė Viktorija , Mečėjus Gediminas
Published: January 2017

Reikšminiai žodžiai: šlapimo nelaikymas dėl įtampos, TOT operacija, patirtis, efektyvumas. Darbo tikslas. Įvertinti įgytos operacinės patirties įtaką šlapimo nelaikymo korekcijos transobturatoriniu raiščiu (TOT operacijos) rezultatams, gydant įtampos šlapimo nelaikymą arba mišrų šlapimo nelaikymą, vyraujant įtampos šlapimo nelaikymui. Darbo metodika. Tai yra prospektyvinis tyrimas, apimantis TOT operacijas, atliktas nuo 2014 m. sausio mėnesio iki 2014 m. gruodžio mėnesio Vilniaus miesto klinikinės ligoninės (VMKL) Ginekologijos skyriuje. Į tyrimą įtraukti visi atvejai, kai pacientėms dėl įtampos arba mišraus šlapimo nelaikymo, vyraujant įtampos šlapimo nelaikymui, atliktos TOT operacijos, implantuojant sintetinį raištį. Indikacija operaciniam gydymui buvo šlapimo nelaikymas dėl įtampos arba mišrus šlapimo nelaikymas, vyraujant įtampos šlapimo nelaikymui. Tyrimo metu buvo pateiktos originalios anketos prieš operaciją ir praėjus metams po jos. Anketose prieš operaciją buvo surinkti pacienčių anamnezės ir gyvenimo kokybės duomenys, o anketose, pateiktose praėjus metams po atliktos operacijos, buvo vertinamas operacijos efektyvumas, pooperacinė eiga ir nepageidaujami požymiai. Gauti rezultatai palyginti su prospektyvinio tyrimo, atlikto 2012 m. VMKL Ginekologijos skyriuje, rezultatais. Rezultatai. 2014 m. iš viso atliktos 98 TOT operacijos. Į tyrimą įtrauktos 54 (55 proc. operuotų) pacientės. Likusios atkrito dėl duomenų trūkumo arba buvo nesurastos praėjus 1 metams po operacijos. Iki operacijos izoliuotas įtampos šlapimo nelaikymas buvo nustatytas 25 (46,3 proc.) pacienčių, mišrus šlapimo nelaikymas, vyraujant įtampos šlapimo nelaikymui, – 29 (53,7 proc.). Po 1 metų 30 (55,6 proc.) pacienčių neliko jokių šlapimo nelaikymo simptomų, 21 (38,9 proc.) pacientei buvo ryškus pagerėjimas, daliai jų su išlikusiais dirgliosios šlapimo pūslės simptomais. Operacijos bendras efektyvumas buvo 94,5 proc. 2012 m. VMKL Ginekologijos skyriuje atliktame tyrime, į kurį buvo įtraukta 40 pacienčių, operacijos efektyvumas praėjus metams po operacijos buvo 92,5 proc.: 57,5 proc. pacienčių neliko jokių šlapimo nelaikymo simptomų ir 35 proc. moterų buvo ryškus pagerėjimas su išlikusiais dirgliosios šlapimo pūslės simptomais. Operacinio gydymo rezultatas didėjant patirčiai yra geresnis, tačiau statistiškai nereikšmingas (p > 0,05). Išvados. TOT operacija gydant įtampos šlapimo nelaikymą yra auksinis standartas, nes efektyvi, saugi, ilgalaikė ir sukelia tik kelias nedideles komplikacijas. Didėjant atliekamų operacijų skaičiui, didėja patirtis ir gerėja operacijos efektyvumas, tačiau priimtini geri rezultatai gaunami net ir po pirmųjų operavimo metų. Šios operacijos mokymosi kreivė yra trumpa.
INKSTŲ ARTERIJOS TROMBOZĖ – KLINIKINIS ATVEJIS IR LITERATŪROS
APŽVALGA
Authors: Skebas Karolis , Vinikovas Artūras
Published: January 2017

Reikšminiai žodžiai: šono skausmas, inkstų arterijos trombozė, laktatdehidrogenazė, antikoaguliantai.
Inkstų arterijos trombozė – reta ir sunkiai diagnozuojama liga, galinti sukelti inkstų infarktą. Ūmi inkstų arterijos trombozė
gali įvykti dėl trombembolijos arba lokalaus aterosklerotinio trombo. Ši liga gali įvairiai pasireikšti kliniškai, nėra patvirtintų
diagnostikos arba gydymo gairių dėl mažo pacientų skaičiaus ir palyginamųjų studijų trūkumo. Tačiau mokslinės literatūros
duomenimis, siūloma įtarti šią ligą esant šono skausmui, hematurijai, padidėjus laktatdehidrogenazės kiekiui kraujo serume
ir diagnozuoti atlikus kompiuterinę tomografiją su kontrastu arba radioizotopinę renografiją. Inkstų arterijos trombozė gali
pasireikšti kaip pielonefritas (karščiavimas ir šono skausmas), inkstų ir šlapimo takų akmenligė (šono skausmas ir hematurija)
arba kliniškai atrodyti kaip ūmus pilvo skausmas. Todėl svarbu žinoti galimus rizikos veiksnius ir būkles, kurios gali turėti
įtakos trombozei atsirasti.
Pristatome inkstų arterijos trombozės klinikinį atvejį Vilniaus miesto klinikinėje ligoninėje. Į priėmimo skyrių kreipėsi 76
metų vyras, skųsdamasis labai stipriais dešiniojo šono skausmais, padidėjusiu kraujospūdžiu, subfebrilia temperatūra, galvos
svaigimu, diskomfortu krūtinės ląstoje. Nežinant tikslios skausmo priežasties, atlikta pilvo ir dubens kompiuterinė tomografija
bei pilvo aortos ir jos šakų kompiuterinė angiografija. Rasta dešiniosios inkstų arterijos pagrindinės šakos distalinės dalies
ir bifurkacijos trombozė bei viršutinio ir vidurinio polių infarktas.
Pateikiame naujausią literatūros apžvalgą apie inkstų arterijos trombozę sukeliančias priežastis, diagnostiką ir gydymą.
HIPOKALCEMIJA ‒ ŽINOMA, BET NEATPAŽĮSTAMA BŪKLĖ. ATVEJO
PRISTATYMAS IR TRUMPA LITERATŪROS APŽVALGA
Authors: Narkutė Airida , Damulevičienė Gytė
Published: January 2017

Reikšminiai žodžiai: hipokalcemija, pirminis hipoparatiroidizmas, ilgas QT intervalas, parkinsonizmas.
Hipokalcemija kliniškai pasireiškia nervų ir raumenų sistemų simptomais: tetanija, traukuliais, laringospazmu, aritmijomis,
sunkina širdies nepakankamumą. Viena hipokalcemijos priežasčių yra pirminis hipoparatiroidizmas ‒ retas endokrininis
sutrikimas, kuriam būdinga hipokalcemija, hiperfosfatemija ir maža parathormono (PTH) koncentracija kraujyje. Hipokalcemiją
taip pat gali sukelti pseudohipoparatiroidizmas, kai PTH koncentracija normali ar padidėjusi, vitamino D trūkumas,
ūminis ir lėtinis inkstų nepakankamumas, pankreatitas, įvairūs medikamentai. Pristatomas paciento, kuriam diagnozuota
simptominė hipokalcemija dėl pirminio hipoparatiroidizmo, klinikinis atvejis. Kliniškai stebėtas traukulių priepuolis, galvos
smegenų EEG registruotas epileptiforminis aktyvumas, EKG ‒ ilgas QT intervalas, o galvos smegenų KT buvo nustatyti kalcinatai
pamato branduolių ir smegenėlių srityse, galimai sukėlę parkinsonizmo simptomus. Skyrus gydymą kalcio gliukonatu
į veną, o vėliau koreguojant hipokalcemiją kalcio karbonatu ir alfakalcidoliu, paciento būklė ženkliai pagerėjo, traukuliai
nesikartojo, tačiau išlaikyti normalią kalcio koncentraciją kraujyje buvo sudėtinga, EKG išliko ilgas QT intervalas. Pacientas
konsultuotas endokrinologo, diagnozuotas pirminis hipoparatiroidizmas. Tolesniam gydymui rekomenduota tęsti kalcio preparatų
ir alfakalcidolio vartojimą, ambulatoriškai monitoruoti kalcio ir fosforo koncentraciją kraujyje.
Modelling several morphometric relationships of swordfish (Xiphias gladius), black marlin (Makaira indica) and blue marlin (Makaira nigricans) caught from Indonesian longliners in the eastern Indian Ocean
Authors: Setyadji Bram , Jatmiko Irwan , Wujdi Arief
Published: January 2017

This paper presents several equations for converting among measures of size (length and weight) for swordfish (Xiphias gladius), black marlin (Makaira indica) and blue marlin (Makaira nigricans) caught by Indonesian longliners in the Indian Ocean. The equations use for transforming non-standard measurement i.e. eye fork length (EFL) and pectoral fork length (PFL) to standard measurement, lower jaw fork length (LJFL). The paper also discussed about the length-weight relationship, including converting from non-standard length (EFL and PFL) to round weight. The result showed that both PFL and EFL were positively related to LJFL but there were no significant differences existed between females and males among length measures for swordfish, blue marlin, and black marlin (ANCOVA, P>0.05). All regression equation models were considered to be valid (P<0.01) with coefficient of determinations (r2) ranged from 0.81-0.99. Allometric growth pattern was statistically observed for all swordfish (b=2.94, r2=0.94), black marlin (b=3.12; r2=0.90) and blue marlin (b=3.30; r2=0.91).
Present status of fish diversity in the Beel Kumari in relation to fish sanctuary and fishing gears
Authors: Joadder Md Abdur Razzaq , Alam Md Bayezid , Siddique Md Abu Bakar , Naim Jannatun
Published: January 2017

The study was conducted on Beel Kumari beel (wetland) in Rajshahi, Bangladesh from October 2013 to September 2014. A total of 52 species of fish were recorded and the dominant species was Mystus tengara (Tanagra (9.75%). Exotic species like bighead carp (Aristichthys nobilis), silver carp (Hypophthalmichthys molitrix) and common carp (Cyprinus carpio) were also commonly found. Of the indigenous species, Ompok bimaculatus, Puntius sarana, Pseudeutropius atherinoides, Botia dario, Mystus aor and Chitala chitala were abundant, though these species were rare before the establishment of the fish sanctuary. Four groups of fishing gears i.e. net, trap, spear and harpoons and line fishing were found to use, among them 8 types of net, 7 types of trap, 4 types of spear and harpoon and 4 types of line fishing were recorded. Among these gill net contributed to the highest catch (32%) and push net was the lowest (6%). Most of the respondents (80%) were found to believe that their fish catch had increased considerably due to impact of fish sanctuary establishment and effective community based fisheries management approach employed in this beel.
Food and feeding behaviour of Mozambique tilapia (Oreochromis mossambicus Peters) from Borna Reservoir of Maharashtra, India
Authors: Sakhare Vishwas Balasaheb , Jetithor Shivaji Gyanba
Published: January 2017

The food analysis of 80 specimens of Oreochromis mossambicus collected from Borna Reservoir of Maharashtra, India revealed that the food  of juveniles mainly consisted of rotifers (35%), followed by copepods (30%), Chlorophyceae (20%), Bacillariophyceae (10%)  and aquatic insects (5%). While the food items recorded in the gut of adults were Chlorophyceae (40%), followed by Bacillariophyceae (30%), rotifers (15%), copepods (10%) and aquatic insects (5%). During present study it was found that the juveniles of O. mossamobicus mainly feed on zooplankton, and adults on phytoplankton. Intense feeding was noticed during summer season and juveniles were the active feeders.
E9: The Fine Resolution Powder Diffractometer (FIREPOD) at BER II
Authors: Franz Alexandra , Hoser Andreas
Published: January 2017

The E9 (FIREPOD) is an upgraded fine resolution powder diffractometer for elastic neutron scattering, obtaining high quality data sets for Rietveld analysis, structure solution and phase analysis under ambient conditions as well as in situ at low / high temperatures, magnetic fields, gas pressure and various atmospheres.
Et me remorsurum petis? Uma promessa de invectiva nos Epodos de Horácio
Authors: Flores Guilherme Gontijo
Published: January 2017

É de grande conhecimento – e tema de rara concordância – entre os classicistas que o poeta romano Quinto Horácio Flaco é um grande ironista. Sua poesia está repleta de duplos sentidos, autoderrisão e logros; mas alguém poderia perguntar o que acontece (ou o que se performa) quando encaramos o gume da ironia em termos de política. Nesse caso, o livro de Epodos, publicado pouco tempo depois da Batalha do Ácio (31 a.C.), pode servir como um exemplo perfeito de como um livro poético seria capaz de apresentar um projeto político complexo por meio das ambages da ironia. Para realizar essa leitura, analisarei aqui os sete primeiros epodos, com ênfase no último deles.
O espetáculo (ὄψις) em Édipo Tirano: o corpo visível
Authors: Colonnelli Marco Valério Classe
Published: January 2017

O presente artigo tem por finalidade analisar o “espetáculo” (ὄψις), a partir das concepções desenvolvidas na Poética de Aristóteles, como parte fundamental na concepção trágica de Sófocles, na obra Édipo Tirano. A análise centrou-se no êxodo da peça para demonstrar como aspectos da representação teatral estão presentes no texto trágico.
"Mirror reads" in Hi-C data
Authors: Galitsyna Aleksandra Alekseevna , Khrameeva Ekaterina Evgenyevna , Razin Sergey Vladimirovich , Gelfand Mikhail Sergeevich , Gavrilov Aleksey Aleksandrovich
Published: January 2017

The detailed analysis of chromatin structure has been enabled due to rapid development of chromosome conformation capture techniques. One of the most popular and widespread variations is high throughput conformation capture, or Hi-C, based on paired-end sequencing. Although a standard data analysis protocol exists to process Hi-C output, some results are still controversially interpreted, for example pairs of reads that are mapped to the same strand of the same restriction fragment. Here we propose the name ”mirror reads” for these cases and investigate possible biological and methodological context of their emergence. We test multiple hypotheses of mirror reads origin, such as genome duplications, replication fork, cohesion of sister chromatids, and homologous chromosome pairing. The current work demonstrates the association of mirror reads with the presence of homologous chromosomes in the nuclei, and homologous pairing. The results support biological relevance of mirror reads.
Integrated toxicogenomics analysis with Toxygates for inferring molecular mechanisms
Authors: Natsume-Kitatani Yayoi , Nyström-Persson Johan , Igarashi Yoshinobu , Satoh Daisuke , Mizuguchi Kenji
Published: January 2017

Assessment of the safety of drug candidates in early research and development (R&D) stage holds the key to the successful drug development. Toxicogenomics is one of the promising approaches using omics techniques since a number of ‘omics databases is rapidly growing. Although many of these databases are open to the public, there remain some barriers for biologists regardless of their bioinformatics skills. Toxygates was originally developed as a user-friendly interface for Open TG-GATEs, which is one of the largest and most widely used toxicogenomics databases. Since the original Toxygates was developed to enable users to display the gene expression values obtained by selected compounds or experimental conditions for genes of interest, there were some limitations as an analytical platform. To overcome this situation, significant improvements have been added and finally, a new version of Toxygates allows users to analyze the data such as creating heatmap for visualization of gene expression profile, performing hierarchical clustering and creating a dendrogram with interactive display, performing several types of enrichment analysis such as gene ontology and pathways and uploading user data for further analysis. As a case study, we used Toxygates to successfully find novel insights that the hepatotoxicity caused by well-studied PPARα agonist WY-14643 may include the disruption of intracellular calcium dynamics and imbalance between PPARα signaling and Wnt signaling.
Demandas e Agendas da Pesquisa em Educação Ambiental no Brasil: sentidos construídos a partir dos relatos dos Grupos de Discussão de Pesquisa em Educação Ambiental (GDPs -EPEAs)
Authors: De Carvalho Luiz Marcelo
Published: January 2017

Estimulado pelos debates que se desenrolaram na mesa redonda Demandas e Agendas de Pesquisa em Educação Ambiental, realizada durante o VIII EPEA, da qual participei, busco, neste artigo, sistematizar algumas análises e reflexões que levei para discussão naquela oportunidade, relacionadas com esse campo de pesquisa. Assim, procuro, inicialmente, explicitar algumas perspectivas metodológicas que escolho como uma alternativa para as possíveis e diversas possibilidades de respostas à questão proposta para a mesa redonda. Tal escolha é o caminho que encontro para vencer as dificuldades iniciais frente à complexidade da temática, certo de que as respostas dadas só poderão ser entendidas como tentativas, provisórias e temporárias, em um contexto particular. Procuro, sinteticamente, fazer menção a algumas estratégias de consolidação e de transformação do campo que a comunidade de pesquisadores em EA tem construído. A partir desse contexto, faço, finalmente, um esforço no sentido de apontar possíveis agendas e demandas que poderiam ser vistas como pertinentes para o campo. Para tal, exploro relatos dos trabalhos dos Grupos de Discussão de Pesquisa (GDPs), que vêm sendo publicados pela revista Pesquisa em Educação Ambiental, desde 2005, e a cada edição do EPEA. A aposta é a de que os resultados desse exercício, realizado pós VIII EPEA, sejam vistos como possíveis elos em uma cadeia de enunciados que concorrem em processos de produção de sentidos sobre o campo da pesquisa em EA no Brasil.
Effect of planting dates and botanical insecticides against majorLepidopterous pests of cabbage: A review
Authors: Dey D. , Routray S. , Baral S. , Mahantheshwara B.
Published: January 2017

Cabbage (Brassicae oleracea var. capitata Linn.) is one of the most important and extensively cultivated vegetable crop because of its nutritional and economical values for producers and consumer point of view, respectively. The crop is prone for infestation by a number of insect pests consisting sucking and defoliating insects starting from germination to harvesting stage of the crop. In India, the diamond back moth, Plutella xylostella Linneaus and cabbage butterfly, Pieris brassicae Linneaus are the major Lepidopterous pests of cabbage. Adjusting planting dates can sometimes help to avoid certain insect infestations and reduce the need for chemical control. Planting dates influence the crop performance due to changed biotic and abiotic factors. The time of planting of cabbage, which is a season bound crop, has profound effect on the incidence of diamond back moth and cabbage butterfly. Several insecticides have been recommended through ages to avert pest damage, but some broad-spectrum synthetic organic insecticides and biopesticides are effective for the control of these two Lepidopterous pests.
Fault and load flows analysis of electricity transmission and distribution system in Casanare (Colombia)
Authors: Castro-Galeano Juan Carlos , Cabra-Sarmiento Wilson Javier , Ortiz-Portilla Jhony Fernando
Published: January 2017

This article describes a simulation of the electrical local distribution and regional transmission system of Enerca S.A. E.S.P. at 34.5 kV and 115 kV, identifying the most critical circuits and substations. The company is located in one of the major petroleum production areas in Colombia, and because of a massive growth in this sector, the electrical company expanded its networks in a radial way. This expansion was improvised and poorly planned due to the accelerated need to meet the new demand, which resulted in stability, balance, voltage regulation, and system reliability problems. Load flow and fault analyses were carried out based on current load and demand predictions in the short and medium term. Twelve proposals were made for network and substation modernization that once implemented will significantly improve the service reliability.
Use of thermal water as a natural coagulant for domestic wastewater sustainable treatment
Authors: Quintero-Jaramillo Javier Andrés , Murillo-Arango Walter , Cerón-Salazar Ivonne Ximena
Published: January 2017

In the last several years, the interest on domestic wastewater treatment has increased due to the rise of water consumption resulted from the world population growth. The excessive use of inorganic coagulants, such as aluminum sulphate, in domestic wastewater treatment processes contributes to generate high negative environmental impacts and risks to living organisms. Besides its low biodegradability, as aluminum sulphate increases metal content in discharged effluents rises, generating toxic sludge. Therefore, searching for clean and sustainable processes for domestic wastewater treatment is important in order to reduce the pollutant discharges into fresh water bodies. In this paper, the potential use of thermal water as a natural coagulant for the domestic wastewater treatment from Manizales city (department of Caldas, Colombia), was studied. The effect of coagulant dose was analyzed and compared with the results of the conventional coagulants. Applying different doses of coagulants in domestic wastewater showed that the best coagulation activity was achieved by adding 35 ml/l of thermal water, and 140 mg/l of aluminum sulphate. In both cases, high turbidity removal efficiency (98.1 %) was achieved. The removal efficiency of Chemical Oxygen Demand (COD) using aluminum sulphate was 81.5 %, and using thermal water was 75.4 %. In conclusion, thermal water has positive coagulation properties; therefore, it is a promising alternative to aluminum sulphate as a natural coagulant on the treatment of domestic wastewater.
Characterization of copper smelter slag and recovery of residual metals from these residues
Authors: Echeverry-Vargas Luver , Rojas-Reyes Néstor Ricardo , Estupiñán Edgar
Published: January 2017

The pyrometallurgical copper extraction process generates 2.2 t of residues for each ton of produced metal. Initially, this paper shows the physical and chemical characterization of a copper processing residue, followed by the procedure to obtain the gold and silver that are contained in the copper residue. The characterization of a white metal oxidized calcine indicates a high content of copper as cupric ferrite, and important values of gold and silver. Gold and silver concentrations were 38.5 g t-1 and 1085 g t-1, respectively. The gold was found scattered in cupric ferrite grains, while the silver was dissolved in a matrix of Cu-S in amounts between 1 % and 50 %. Cyanidation tests showed that 95 % gold recovery could be obtained with a concentration of 0.06 g l-1 KCN, a pH of 10.5, room temperature, and a residence time of 80 h. When the temperature was increased to 75 °C, and the other cyanidation parameters were maintained intact, the same recovery was obtained but with a shorter residence time. Silver recovery was less than 30 % with a concentration of 1.2 g l-1 KCN, pH of 10.5, temperature of 45 °C, and a residence time longer than 72 h.
Spin Coating technique for obtaining nanometric thin films in the system La0.7Sr0.3MnO3
Authors: Mera-Córdoba Jenny Alejandra , Mera-Córdoba María Angélica , Córdoba-Barahona Carlos Arturo
Published: January 2017

Manganite in the La0.7Sr0.3MnO3 system is of great interest due to its potential application in fuel cells, information storage, magnetic field sensors, non-volatile memories, oxygen sensors, and catalysts in the oxidation of light hydrocarbons. Given the scientific relevance of this material, this study describes the procedure to synthesize and characterize thin films of La0.7Sr0.3MnO3. Manganites were synthesized by means of the Pechini method, and deposited on strontium titanate substrates using spin-coating. Both the crystallinity of the films and their phases were studied with X-ray diffraction (XRD), finding that the films are polycrystalline and have a simple cubic structure with a lattice constant a=3.8653 ± 0.066 Ǻ. Scanning electron microscopy (SEM) showed a uniform surface with good morphological features, and the spectrum resulted from the Energy Dispersive X-Ray Spectroscopy (EDS) analysis over the same film was consistent with the molar ratio of the perovskite. Samples of 2, 4, and 6 layers were synthesized, obtaining thicknesses of 75.10 ± 0.01, 75.02 ± 0.01 and 74.07 ± 0.08 nm per monolayer. The results indicate that this method is useful to synthesize films of high crystalline quality and nanometric size.
Synthetic fuel production from shredded scrap waste
Authors: Barragán-Gutiérrez Iván Ernesto , López-Díaz Alfonso , Krumm Wolfgang
Published: January 2017

This technological innovation project involved material identification, and design, installation, implementation, and evaluation of a pilot plant with capacity of 10 t per batch to recover materials and produce synthetic fuels (oil, syngas and solid) from shredded scrap waste. The results showed the proper way to separate materials (metals, and organic and inert compounds), and to perform the pyrolysis process to produce gas, oil, and coke as synthetic fuels from organic waste. The process started with the physicochemical characterization of the waste, followed by the selection of separation, sorting and processing technologies, and the definition of pyrolysis process parameters. Finally, the synthetic fuels were characterized, and uses for the furnace billet, ladle preheating, internal combustion engines, and auto generation were suggested. The results showed 82 % recovery of magnetic and non-magnetic metals, and production of synthetic fuels with PCI between 20 650 and 36 900 kJ/kg.
Transcrição da tinta ao braille: apontamentos de algumas diferenças semio-cognitivas
Authors: Moretti Méricles Thadeu , Dos Anjos Daiana Zanelato
Published: January 2017

Preocupamo-nos, neste trabalho, com a aprendizagem matemática por estudantes cegos. Buscamos analisar duas ferramentas utilizadas em sala de aula para estes estudantes: o Livro Didático de Matemática em Braille (LDMB) e o Código Matemático Unificado (CMU) para a Língua Portuguesa. Os seguintes questionamentos foram o fio condutor no estudo da transcrição do livro didático impresso em tinta para o livro em Braille: em que condições esta transcrição é elaborada? Que diferenças semio-cognitivas importantes surgem? O que ocorre com as expressões matemáticas envolvidas? Apontaremos, neste estudo, diversas dificuldades de aprendizagem matemática que podem ter origem nessas transformações semióticas.
Mexican conifers differ in their capacity to face climate change
Authors: Sáenz-Romero Cuauhtémoc , Larter Maximilien , González-Muñoz Noelia , Wehenkel Christian , Blanco-Garcia Arnulfo , Castellanos-Acuña Dante , Burlett Regis , Delzon Sylvain
Published: January 2017

The recent massive dieback of forest trees due to drought stress makes assessment of the variability of physiological traits that might be critical for predicting forest response and adaptation to climate change even more urgent. We investigated xylem vulnerability to cavitation and xylem specific hydraulic conductivity in seven species of three principal conifer genera (Juniperus monticola, Juniperus deppeana, Juniperus flaccida, Pinus pseudostrobus, Pinus leiophylla, Pinus devoniana, and the endangered Picea chihuahuana) of the Mexican mountains in order to identify the species most vulnerable to future warmer and drier climates. Hydraulic traits were examined using the in situ flow centrifuge technique (Cavitron) on branches collected from adult trees of natural populations and seedlings growing in a common garden. We found evidence of significant differences in xylem safety between genera (P50: pressure inducing 50% loss of hydraulic conductance): the three juniper species exhibited low P50 values (ranging from -9.9 to -10.4 MPa), relative to the much more vulnerable pine and spruce species (P50 ranging between - 2.9 to - 3.3 MPa).  Our findings also revealed no variation in P50 between adult trees assessed in the field and seedlings growing in a common garden. We therefore propose that if, as projected, climate change makes their natural habitats much warmer and drier, populations of Mexican pines and the studied spruce will be likely to decline severely as a result of drought-stress induced cavitation, while the juniper species will survive.
Predicting Some Physicochemical Properties of Octane Isomers: A Topological Approach Using ev-Degree and ve-Degree Zagreb Indices
Authors: Ediz Süleyman
Published: January 2017

Topological indices have important role in theoretical chemistry for QSPR researches. Among the all topological indices the Randić and the Zagreb indices have been used more considerably than any other topological indices in chemical and mathematical literature. Most of the topological indices as in the Randić and the Zagreb indices are based on the degrees of the vertices of a connected graph. Recently novel two degree concepts have been defined in graph theory; ev-degrees and ve-degrees. In this study we define ev-degree Zagreb index, ve-degree Zagreb indices and ve-degree Randić index by using these new graph invariants as parallel to their corresponding classical degree versions. We compare these new group ev-degree and ve-degree indices with the other well-known and most used topological indices in literature such as; Wiener, Zagreb and Randić indices by modelling some physicochemical properties of octane isomers. We show that the ev-degree Zagreb index, the ve-degree Zagreb and the ve-degree Randić indices give better correlation than Wiener, Zagreb and Randić indices to predict the some specific physicochemical properties of octanes. We investigate the relations between the second Zagreb index and ev-degree and ve-degree Zagreb indices and some mathematical properties of ev-degree and ve-degree Zagreb indices.
Facial Expression Recognition with Fusion Features Extracted from Salient Facial Areas
Authors: Liu Yanpeng , Li Yibin , Ma Xin , Song Rui
Published: January 2017

In pattern recognition domain, deep architectures are widely used nowadays and they have achieved fine grades. However, these deep architectures need special demands, especially big datasets and GPU. Aiming to gain better grades without deep networks, we propose a simplified algorithm framework using fusion features extracted from the salient areas of faces. Furthermore, the proposed algorithm has achieved a better result than some deep architectures. For extracting more effective features, this paper firstly defines the salient areas on the faces. This paper normalizes the salient areas of the same location in the faces to the same size, therefore it can gain more similar features from different subjects. LBP and HOG features are extracted from the salient areas, fusion features’ dimensions are reduced by Principal Component Analysis( PCA) and we apply softmax to classify the six basic expressions at once. This paper proposes a salient areas definitude method which uses peak expressions frames to compare with their neutral faces. This paper also proposes and applies the idea of normalizing the salient areas to align the specific areas which express the different expressions. This makes the salient areas found from different subjects have the same size. Besides, gamma correction method is firstly applied on LBP features in our algorithm framework which improves our recognition rates significantly. By applying this algorithm framework, our research has gained state-of-the-art performances on CK+ database and JAFFE database.
Suplementasi L-Karnitin dan Asam Lemak PUFA Terproteksi dalam Ransum Limbah Pasar Organik Terfermentasi Pengaruhnya Terhadap Komposisi Kimiawi Air Susu Kambing
Authors: Sudibya Sudibya , Hanifa Aqni , Handayanta Eka , Intansari Ayu , Hadi Rendi Fathoni
Published: January 2017

The experiment was conducted to investigate the effect of transfer protection PUFA and L-carnitin on the ration on chemist composition of dairy milk In total, 15 female dairy goats of 2-4 year this old Peranakan Etawah (PE) with body weight of 25-55 kg were used in this experiment. The assay diets included a basal diet (control) based on yellow corn, rice bran, soy bean meal and coconut meal, mineral, tuna fish oil and lemuru fish oil. The method of the research was experimental in vivo using Completely Randomized Blok Design (RAK). There were 5 treatment in each treatment and 3 replication. Treatment consisted of P0 = control ration, P1 = P0 +50% market waste subtition grass on the ration, P2 = P1+500 ppm L-karnitin on the ration, P3 = P1+protection tuna fish oil 5% in the ration and P4 = P1+ protection lemuru fish oil 5% in the ration. The variables measuared content composition dairy milk goat. The results of variance analysis showed that the effect of suplementation protection PUFA in the rations on market waste contain 500 ppm L-carnitine were significantly (P<0.01) of acid goats milk composition. The conclusion of this research shows that the suplementation protection PUFA in the ration contain 500 ppm L-carnitine, can decrease milk cholesterol from 0,482% to 0,420%, LDL from 45,30 to 33,13 mg/dl. There for to increase HDL from 54,70 to 66,87 mg/dl, omega-3 fatty acid from 1,10% to 4,04%, omega-6 fatty acid from 1,46% to 18,80 percent.

 

Keywords: composition dairy milk goats, L-carnitine, protection PUFA fatty acid
Pengaruh Suplementasi Probiotik dalam Ransum Terhadap Kualitas Fisik Daging Itik
Authors: Wahyuni Dyah , Arisuteja Sofi , Sandi Sofia , Yosi Fitra
Published: January 2017

This research aim to find out the effect of probiotic in ration on physical quality (pH, water holding capacity, cooking loss and tenderness) of duck meat. The materials used was local duck supplemented probiotic into ration. Research’s method used was Completely Randomize Design (CRD) consisted of 7 treatments and 4 replications namely P1(basic ration/ control), P2 (basic ration+probiotic), P3 (basic ration+infected by E.coli), P4 (basic ration+infected by Salmonella), P5 (basic ration+probiotic+infected by E.coli), P6 (basic ration+ probiotic+infected by Salmonella) and P7 (basic ration+probiotic+infected by E.coli+Infected by Salmonella). The results showed that probiotic suplementation about 106 cfu/ml into ration were no significantly effect on physical quality (pH, water holding capacity, cooking loss and tenderness) of duck meat.

 

Keywords: probiotic, ration, physical quality, meat, duck
Minimalisasi Biaya Transportasi Pada Sistem Pasokan Salak Pondoh (Salacca Edulis, Reinw.Cv.) Di Kabupaten Sleman, Yogyakarta
Authors: Setyadjit NFN , Risfaheri NFN
Published: January 2017

Salak pondoh saat ini menjadi komoditas prospektif bagi petani di Kabupaten Sleman, Yogyakarta. Permintaan Salak dari negara-negara importir setiap tahunnya terus meningkat sehingga kualitas, kuantitas, kontinuitas dan bahkan komitmen setiap pemasok mutlak diperlukan. Salah satu isu penting dalam rantai pasokan agribisnis salak adalah pengelolaan salak dari petani ke asosiasi yang belum efisien dan terstruktur dengan baik, sehingga perlu dikaji secara mendalam dengan melibatkan para pelaku rantai pasokan. Penelitian ini bertujuan untuk meminimalkan biaya transportasi dan implikasinya terhadap manajemen transportasi yang terkait dengan waktu panen salak. Metode yang digunakan adalah Spanning Tree Minimum (MST) dan Linear Programming Fuzzy (FLP). Hasil penelitian menunjukkan bahwa penggunaan FLP untuk analisis biaya transportasi lebih rendah dari pada menggunakan Linear Programming konvensional, meskipun ada beberapa batasan sistem yang dilanggar. Biaya transportasi minimum untuk Mitra Turindo dan Prima Sembada setiap tahunnya masing-masing sebesar Rp547.522.200 dan Rp.422.030.200, dan fungsi keanggotaannya masing-masing adalah 0,9 dan 0,8.