bluuebunny/crossref_metadata_2025 huggingface dataset:
Astringency Sensitivity to Tannic Acid: Effect of Ageing and Saliva
Authors: Wang Mei , Septier Chantal , Brignot Hélène , Martin Christophe , Canon Francis , Feron Gilles
Published: March 2022

Astringency is an important sensory characteristic of food and beverages containing polyphenols. However, astringency perception in elderly people has not been previously documented. The aim of the present work was to evaluate sensitivity to astringency as a function of age, salivary flow and protein amount. Fifty-four panellists, including 30 elderly people (age = 75 ± 4.2 years) and 24 young people (age = 29.4 ± 3.8 years), participated in this study. Astringency sensitivity was evaluated by the 2-alternative forced choice (2-AFC) procedure using tannic acid solutions. Whole saliva was collected for 5 min before and after the sensory tests. The results showed that the astringency threshold was significantly higher in the elderly group than the young group. No correlation was observed between the salivary protein amount and threshold value. However, a negative correlation between salivary flow and threshold was observed in the young group only. These results showed a difference in oral astringency perception as a function of age. This difference can be linked to salivary properties that differ as a function of age.
Supported Ionic Liquids Used as Chromatographic Matrices in Bioseparation—An Overview
Authors: Bernardo Sandra C. , Carapito Rita , Neves Márcia C. , Freire Mara G. , Sousa Fani
Published: March 2022

Liquid chromatography plays a central role in biomanufacturing, and, apart from its use as a preparative purification strategy, either in biopharmaceuticals or in fine chemicals industries, it is also very useful as an analytical tool for monitoring, assessing, and characterizing diverse samples. The present review gives an overview of the progress of the chromatographic supports that have been used in the purification of high-value products (e.g., small molecules, organic compounds, proteins, and nucleic acids). Despite the diversity of currently available chromatographic matrices, the interest in innovative biomolecules emphasizes the need for novel, robust, and more efficient supports and ligands with improved selectivity. Accordingly, ionic liquids (ILs) have been investigated as novel ligands in chromatographic matrices. Given herein is an extensive review regarding the different immobilization strategies of ILs in several types of supports, namely in silica, Sepharose, and polymers. In addition to depicting their synthesis, the main application examples of these supports are also presented. The multiple interactions promoted by ILs are critically discussed concerning the improved selectivity towards target molecules. Overall, the versatility of supported ILs is here considered a critical point to their exploitation as alternatives to the more conventional liquid chromatographic matrices used in bioseparation processes.
Microstructure Evolution and Properties Induced by Multi-Pass Drawing of Graphene/Copper Nanocomposite
Authors: Wang Miao , Sheng Jie , Xing Changsheng , Wang Gang , Duan Yuanpei , Wang Lidong
Published: March 2022

The influence of multi-pass cold drawing on the evolution of microstructure, texture, and properties of Cu matrix composite, reinforced by in situ grown graphene, has been systematically investigated. Under continuous and severe plastic deformation, the grains in the composite were continuously refined to nanoscale. In addition, graphene in the composite could be gradually refined, exfoliated, and redispersed. Interestingly, dynamic recrystallization of the composite was formed after 80% drawing reduction and its formation mechanism was discussed. The texture of the as-drawn composite comprised a mixture of fiber textures with dominated <111> and minor <100> orientation after 99.7% severe drawing reduction. The tensile properties and electrical conductivity of the as-drawn composites were also investigated. This work provides a better guideline on the plastic deformation behavior of the advanced graphene/metal nanocomposite.
Machine Learning-Assisted Dual-Marker Detection in Serum Small Extracellular Vesicles for the Diagnosis and Prognosis Prediction of Non-Small Cell Lung Cancer
Authors: Li Wenzhe , Zhu Ling , Li Kaidi , Ye Siyuan , Wang Huayi , Wang Yadong , Xue Jianchao , Wang Chen , Li Shanqing , Liang Naixin , Yang Yanlian
Published: March 2022

Small extracellular vesicles (sEVs) carry molecular information from their source cells and are desired biomarkers for cancer diagnosis. We establish a machine learning-assisted dual-marker detection method to analyze the expression of epidermal growth factor receptor (EGFR) and C-X-C chemokine receptor 4 (CXCR4) in serum sEVs for the diagnosis and prognosis prediction of non-small cell lung cancer (NSCLC). We find that the serum sEV EGFR and CXCR4 are significantly higher in advanced stage NSCLC (A/NSCLC) patients compared to early stage NSCLC (E/NSCLC) patients and the healthy donors (HDs). A receiver operating characteristic curve (ROC) analysis demonstrates that the combination of EGFR and CXCR4 in serum sEVs as an efficient diagnostic index and malignant degree indicator for NSCLC. Machine learning further shows a diagnostic accuracy of 97.4% for the training cohort and 91.7% for the validation cohort based on the combinational marker. Moreover, this machine leaning-assisted serum sEV analysis successfully predicts the possibility of tumor relapse in three NSCLC patients by comparing their serum sEVs before and three days after surgery. This study provides an intelligent serum sEV-based assay for the diagnosis and prognosis prediction of NSCLC, and will benefit the precision management of NSCLC.
Efficacy of Gold Nanoparticles against Drug-Resistant Nosocomial Fungal Pathogens and Their Extracellular Enzymes: Resistance Profiling towards Established Antifungal Agents
Authors: Almansob Abobakr , Bahkali Ali H. , Ameen Fuad
Published: March 2022

Drug resistance of filamentous fungi to the commonly used antifungal agents is a major concern in medicine. Therefore, an effective approach to treat several opportunistic fungal infections is the need of the hour. Mentha piperita is used in home remedies to treat different disorders. Isolates of fungi were taken from hospitals in Riyadh, Saudi Arabia, and identified using molecular tools. Amphotericin B, Voriconazole, and Micafungin were applied to screen the resistance of these isolates using both disc and broth microdilution techniques. An aqueous extract of Mentha piperita was utilized to synthesize AuNPs and the nanoparticles were characterized using UV-Vis, FTIR, TEM, EDAX, and XRD. The AuNPs were tested for antifungal activity against the nosocomial fungal pathogens and the activity of extracellular enzymes of such pathogens were analyzed after treatment with AuNPs. We conclude that AuNPs synthesized using Mentha piperita do not possess especially effective antifungal properties against multi-drug resistant Aspergillus species. Five out of eighteen isolates were inhibited by AuNPs. When inhibition was observed, significant alterations in the activity profile of extracellular enzymes of the nosocomial fungi were observed.
A Facile Pre-Lithiated Strategy towards High-Performance Li2Se-LiTiO2 Composite Cathode for Li-Se Batteries
Authors: Xia Yang , Fang Zheng , Lu Chengwei , Xiao Zhen , He Xinping , Gan Yongping , Huang Hui , Wang Guoguang , Zhang Wenkui
Published: March 2022

Conventional lithium-ion batteries with a limited energy density are unable to assume the responsibility of energy-structure innovation. Lithium-selenium (Li-Se) batteries are considered to be the next generation energy storage devices since Se cathodes have high volumetric energy density. However, the shuttle effect and volume expansion of Se cathodes severely restrict the commercialization of Li-Se batteries. Herein, a facile solid-phase synthesis method is successfully developed to fabricate novel pre-lithiated Li2Se-LiTiO2 composite cathode materials. Impressively, the rationally designed Li2Se-LiTiO2 composites demonstrate significantly enhanced electrochemical performance. On the one hand, the overpotential of Li2Se-LiTiO2 cathode extremely decreases from 2.93 V to 2.15 V. On the other hand, the specific discharge capacity of Li2Se-LiTiO2 cathode is two times higher than that of Li2Se. Such enhancement is mainly accounted to the emergence of oxygen vacancies during the conversion of Ti4+ into Ti3+, as well as the strong chemisorption of LiTiO2 particles for polyselenides. This facile pre-lithiated strategy underscores the potential importance of embedding Li into Se for boosting electrochemical performance of Se cathode, which is highly expected for high-performance Li-Se batteries to cover a wide range of practical applications.
Glia Excitation in the CNS Modulates Intact Behaviors and Sensory-CNS-Motor Circuitry
Authors: McCubbin Shelby , Harrison Douglas A. , Cooper Robin L.
Published: March 2022

Glial cells play a role in many important processes, though the mechanisms through which they affect neighboring cells are not fully known. Insights may be gained by selectively activating glial cell populations in intact organisms utilizing the activatable channel proteins channel rhodopsin (ChR2XXL) and TRPA1. Here, the impacts of the glial-specific expression of these channels were examined in both larval and adult Drosophila. The Glia > ChR2XXL adults and larvae became immobile when exposed to blue light and TRPA1-expressed Drosophila upon heat exposure. The chloride pump expression in glia > eNpHR animals showed no observable differences in adults or larvae. In the in situ neural circuit activity of larvae in the Glia > ChR2XXL, the evoked activity first became more intense with concurrent light exposure, and then the activity was silenced and slowly picked back up after light was turned off. This decrease in motor nerve activity was also noted in the intact behaviors for Glia > ChR2XXL and Glia > TRPA1 larvae. As a proof of concept, this study demonstrated that activation of the glia can produce excessive neural activity and it appears with increased excitation of the glia and depressed motor neuron activity.
The Role of Plant Growth Promoting Rhizosphere Microbiome as Alternative Biofertilizer in Boosting Solanum melongena L. Adaptation to Salinity Stress
Authors: Mokabel Souhair , Olama Zakia , Ali Safaa , El-Dakak Rehab
Published: March 2022

Recent ecological perturbations are presumed to be minimized by the application of biofertilizers as a safe alternative to chemical fertilizers. The current study aims to use bioinoculum (I) as an alternative biofertilizer and to alleviate salinity stress in the cultivar Solanum melongena L. Baldi. The salinity drench was 200 mM NaCl (S), which was used with different treatments (0; I; S; S + I) in pots prefilled with clay and sand (1:2). Results showed that salinity stress inhibited both plant fresh and dry weights, water content, and photosynthetic pigments. The content of root spermine (Spm), spermidine (Spd), and puterscine (Put) decreased. However, addition of the bioinoculum to salt-treated plants increased pigment content (80.35, 39.25, and 82.44% for chl a, chl b, and carotenoids, respectively). Similarly, K+, K+/Na+, Ca2+, P, and N contents were significantly enhanced. Increases were recorded for Spm + Spd and Put in root and shoot (8.4-F, 1.6-F and 2.04-F, 2.13-F, respectively). RAPD PCR showed gene expression upregulation of photosystem II D2 protein, glutathione reductase, glutathione-S-transferase, protease I, and protease II. The current work recommends application of the selected bioinoculum as a green biofertilizer and biopesticide. Additionally, the studied eggplant cultivar can be regarded as a source of salt tolerance genes in agricultural fields.
Shape-Memory Materials via Electrospinning: A Review
Authors: Salaris Valentina , Leonés Adrián , Lopez Daniel , Kenny José Maria , Peponi Laura
Published: March 2022

This review aims to point out the importance of the synergic effects of two relevant and appealing polymeric issues: electrospun fibers and shape-memory properties. The attention is focused specifically on the design and processing of electrospun polymeric fibers with shape-memory capabilities and their potential application fields. It is shown that this field needs to be explored more from both scientific and industrial points of view; however, very promising results have been obtained up to now in the biomedical field and also as sensors and actuators and in electronics.
Connecting Text Classification with Image Classification: A New Preprocessing Method for Implicit Sentiment Text Classification
Authors: Chen Meikang , Ubul Kurban , Xu Xuebin , Aysa Alimjan , Muhammat Mahpirat
Published: March 2022

As a research hotspot in the field of natural language processing (NLP), sentiment analysis can be roughly divided into explicit sentiment analysis and implicit sentiment analysis. However, due to the lack of obvious emotion words in the implicit sentiment analysis task and because the sentiment polarity contained in implicit sentiment words is not easily accurately identified by existing text-processing methods, the implicit sentiment analysis task is one of the most difficult tasks in sentiment analysis. This paper proposes a new preprocessing method for implicit sentiment text classification; this method is named Text To Picture (TTP) in this paper. TTP highlights the sentiment differences between different sentiment polarities in Chinese implicit sentiment text with the help of deep learning by converting original text data into word frequency maps. The differences between sentiment polarities are used as sentiment clues to improve the performance of the Chinese implicit sentiment text classification task. It does this by transforming the original text data into a word frequency map in order to highlight the differences between the sentiment polarities expressed in the implicit sentiment text. We conducted experimental tests on two common datasets (SMP2019, EWECT), and the results show that the accuracy of our method is significantly improved compared with that of the competitor’s. On the SMP2019 dataset, the accuracy-improvement range was 4.55–7.06%. On the EWECT dataset, the accuracy was improved by 1.81–3.95%. In conclusion, the new preprocessing method for implicit sentiment text classification proposed in this paper can achieve better classification results.
Precise Target Geo-Location of Long-Range Oblique Reconnaissance System for UAVs
Authors: Zhang Xuefei , Yuan Guoqin , Zhang Hongwen , Qiao Chuan , Liu Zhiming , Ding Yalin , Liu Chongyang
Published: March 2022

High-precision, real-time, and long-range target geo-location is crucial to UAV reconnaissance and target strikes. Traditional geo-location methods are highly dependent on the accuracies of GPS/INS and the target elevation, which restricts the target geo-location accuracy for LRORS. Moreover, due to the limitations of laser range and the common, real time methods of improving the accuracy, such as laser range finders, DEM and geographic reference data are inappropriate for long-range UAVs. To address the above problems, a set of work patterns and a novel geo-location method are proposed in this paper. The proposed method is not restricted by conditions such as the accuracy of GPS/INS, target elevation, and range finding instrumentation. Specifically, three steps are given, to perform as follows: First, calculate the rough geo-location of the target using the traditional method. Then, according to the rough geo-location, reimage the target. Due to errors in GPS/INS and target elevation, there will be a re-projection error between the actual points of the target and the calculated projection ones. Third, a weighted filtering algorithm is proposed to obtain the optimized target geo-location by processing the reprojection error. Repeat the above process until the target geo-location estimation converges on the true value. The geo-location accuracy is improved by the work pattern and the optimization algorithm. The proposed method was verified by simulation and a flight experiment. The results showed that the proposed method can improve the geo-location accuracy by 38.8 times and 22.5 times compared with traditional methods and DEM methods, respectively. The results indicate that our method is efficient and robust, and can achieve high-precision target geo-location, with an easy implementation.
“Lots of Time They Don’t Pay”: Understanding Wage-Theft and Resistance in Bryan, Texas through Critical Community-Engaged Research
Authors: Plankey-Videla Nancy , Cisneros Franco Cynthia Luz
Published: March 2022

This critical community-engaged mixed methods study quantifies worker mistreatment on day labor corners in Bryan, Texas, and examines how day laborers resist labor exploitation. Day laborers seek work in open air spot markets. The work is precarious, with temporary and unregulated employment relations, weak enforcement, and poor working conditions. In this weak penalty and labor enforcement regime, labor violations are not surprising. Contrary to dominant theories, however, we argue that demand-side (industry) characteristics are more important for explaining the prevalence of labor violation than supply-side (worker characteristics). We use the Central Texas Day Labor Survey (2012–2021), 210 ethnosurveys consisting of 55% unauthorized workers, 24% authorized workers, and 20% Latinx, Black, and White citizens. We find that higher indices of labor violations and work abuse are not associated with lower-status workers; all workers, irrespective of legal status or citizenship, experienced abuse by employers. Demand-side characteristics were partially associated with higher levels of wage theft and mistreatment. In terms of wages, we found a gradation of wages with the lowest for unauthorized immigrants, then authorized immigrants, Latinx citizens, Black citizens, and lastly White citizens. Finally, workers collectively fight back against injustice by warning each other about unscrupulous employers.
Exact Treatment of the Ground States of Three Two-Dimensional Contact Interactions in a Uniform Magnetic Field
Authors: Glasser Mervyn Lawrence
Published: March 2022

The Green function for an electron confined to a plane in the presence of a uniform perpendicular magnetic field is derived and is decorated by several modified Dirac delta functions (MDF). In each case the ground state energy is examined as a function of the field strength, the spacing and the coupling constant of the MDFs. The results suggest that the magnetic field is ionising and the strength of the MDFs must attain a field-dependent critical value in order that a bound state be formed. This offers a new perspective on the question of whether a static magnetic field can be ionising.
PENGARUH REKRUTMEN, PENGATURAN STAF DAN PENGEMBANGAN KARIER TERHADAP KINERJA KARYAWAN
Authors: Nurdin Muhammad
Published: March 2022

The development of tertiary education is now facing a lot of attention, especially in the current condition where there is obligation to work at least at undergraduate education level. Good quality employees are hired to advance education. So it is necessary to assess employee performance through a study conducted at the Indonesian College of Management (STIMI) Banjarmasin. This research uses quantitative research techniques. The sample is same as population, which is all existing employees (lecturers and academic staff) because of small population (overall). Data collection techniques are through statements distributed in the questionnaire. Data is analyzed by linear regression analysis. Recruitment, staffing and career developments in this study are in accordance with the real and present phenomena. When the recruitment, staffing and career developments are conducted well, it is expected to create good performances also. Therefore, it will make this institution survive sustainably in the future.
EXPLORATORY FACTOR ANALYSIS (EFA) OF PERFORMANCE OF SMES
Authors: - Dede Ansyari Guci
Published: March 2022

Performance of SMEs in Indonesia has been a lot of research on previous study. The objective of this research is to develop an idea for calculate performance of SMEs. As many as 100 respondents of pilot test of  SME players in Medan, Indonesia. The validation method aimed at validating the parameters  which  calculate each of the constructs by statitiscally determining that the sample is adequate, using KMO and barlett’s test to confirm the effectiveness of the data for multivariate statistical analysis, validating the calculation requirements as applicable to performance of SMEs adept. The result show that the data is valid and reliable design.
FAKTOR RECEIVABLE TURNOVER, CURRENT RATIO DAN DEBT TO EQUITY RATIO TERHADAP RETURN ON ASSET PADA PERUSAHAAN SEKTOR TRADE, SERVICES AND INVESTMENT
Authors: - Khana Saputri
Published: March 2022

This study aims to examine the factors of Receivable Turnover, Current Ratio and Debt To Equity Ratio to Return On Assets in Trade, Services and Investment Sector Companies. The research approach used in this research is quantitative research. The population that will be used in this research is the Trade, Service and Investment companies in the Indonesia Stock Exchange totaling 111 companies with 60 observational data. The results of the research show that Receivable Turnover has no significant effect, Current Ratio has a significant positive effect, Debt to Equity Ratio has a significant positive effect partially. Receivable Turnover, Current Ratio, and Debt to Equity Ratio simultaneously affect Return On Asset in Trade, Service and Investment sector companies listed on the Indonesia Stock Exchange. Meanwhile, the coefficient of determination is 15.9%.
PENGARUH PROMOSI, KUALITAS PELAYANAN DAN KUALITAS PRODUK TERHADAP KEPUTUSAN MENABUNG PADA BANK SUMUT
Authors: Zebua Berliana Juniscahyanti Zebua , Andronicus Melkyory
Published: March 2022

The purpose of this research is to analyze how the influence of promotion, service quality, and product quality on the saving decision at Bank Sumut. decrease in customer levels was due to inappropriate promotions, service quality, and product quality. the sample in this research amount to 119 employees. The results of partial hypothesis testing obtained tcount>ttable 3,791 > 1,980 with a significant value of 0.016<0.05, tcount > ttable or 2,301 > 1,980 with a significant value of 0.021 < 0.05, and tcount > ttable or 4.931 > 1.980 with a significant value 0.000 < 0.05. Fcount (10.014) > Ftable (2.45) and significance probability 0.000 < 0.05. The results of the coefficient of determination test obtained the Adjusted R Square value of 0.476, this means 47.6% of the dependent variable, namely the saving decision which can be explained by the independent variables, namely promotion, service quality, and product quality. The conclusion in this research is that partially and simultaneously the variables of promotion, service quality, and product quality have a positive and significant effect on saving decisions at Bank Sumut.
När begäret går överstyr:
Authors: Dziedzic Dominik
Published: March 2022

I denna artikel prövas en läsning av Viktor Rydbergs Singoalla ur ett skevperspektiv. Fokus sätts på barnkonstruktionen i texten. Singoalla presenteras som en hybrid- roman med skräckromantiska inslag, vilket påverkar hur karaktären Sorgbarn, sonen till huvudprotagonisterna Singoalla och Erland, konstrueras. Genom att det skräckromantiska lyfts fram diskuteras Sorgbarn som en skev gestalt som avviker från den idealistiska norm utifrån vilken barnframställningen i Rydbergs litterära produktion annars konstrueras. Med Sorgbarns skevhet avses att han,

till skillnad från de idealiserade barngestalterna i Rydbergs övriga författarskap, förmedlar och genererar begär som inte låter sig harmoniskt integreras i hand- lingen. Gossens skevhet diskuteras i relation till det kusliga, det monstruösa och queera begär. Sorgbarns blotta närvaro i sin far Erlands slott leder till ett förfall av Erlands psyke, vilket i denna artikel diskuteras genom Freuds husmetafor. Romanen läses som en text som handlar om att förlora kontrollen över begär, förmedlade och genererade genom pojkkroppen.
Épidémies, dieux et rites à Rome / Epidemics, Gods, and Rituals in Rome
Authors: Van Haeperen Françoise
Published: March 2022

Cet article est consacré aux perceptions et réponses religieuses que les Romains ont développées face aux épidémies. L’étude s’appuie principalement sur l’oeuvre de Tite-Live, la plus riche à cet égard, qui est complétée par quelques passages d’autres auteurs. Outre les cérémonies, traditionnelles ou novatrices, spontanées ou dictées par les autorités, auxquelles les épidémies donnent lieu, nous envisageons la perception de ces pestilences en termes de châtiment divin, ces fléaux pouvant être interprétés comme des prodiges manifestant l’ira deum, la colère des dieux. Nous nous interrogeons également sur la fonction étiologique que certains de ces épisodes peuvent revêtir : certains présentent, en la situant dans un passé lointain marqué par une épidémie, l’origine de plusieurs cérémonies.
Anticoagulant treatment and COVID-19
Authors: ÖZDEMIR İbrahim Halil , ÖZEN Mehmet Burak , GÜNDÜZ Ramazan
Published: March 2022

Objective: In this study, we aimed to examine the effect of atrial fibrillation (AF) on mortality in COVID-19 patients and the risk scores that can be used in determining risky AF patients. In addition, we aimed to examine the place of oral anticoagulant use in treatment.

Materials and Methods: Records of patients diagnosed with COVID-19 were retrospectively reviewed. Among these patients, 48 patients with a diagnosis of AF were identified. Intensive care need, mortality, CHA2DS2VASC and HAS-BLED scores of the patients were recorded. CRP and D-Dimer levels were recorded. Oral anticoagulant treatments used by the patients were recorded.

Results: The CHA2DS2VASC (intensive care: 4,50±1,41, internal medicine service: 2,50±1,05, p
Aşı Paradoksu
Authors: ÇELİK Çetin , ATEŞ Mehmet
Published: March 2022

Aşı bilindiği üzere bulaşıcı hastalıklarla mücadelede önemli bir yer tutmaktadır. İçinde bulunduğumuz pandemi sürecinde aşının hastalıkla mücadelede ne denli önemli bir silah olduğunun önemi bir kez daha anlaşılmıştır. Şu an yapılmakta olan aşı tedarik zinciri süreçleri ve aşılama stratejilerinin dezavantajlı olduğu gözlenmektedir. Aşı tedarik zincirinde yer alan “Aşı dozu üretimi” sürecinde aşı için gerekli olan yeterli antijenin üretilmemesinden kaynaklanmaktadır. Aşının bireylere uygulanabilmesi için sağlık personeline ve uygulama yerlerine ihtiyaç duyulmaktadır. Yaşadığımız bu süreçte de görüldüğü gibi toplumsal aşılamada fazla zaman ve kaynağa gerek duyulmaktadır. Pandeminin yeni tanımına bakıldığında elimizdeki kaynakların (malzeme ve insan) yetersiz kalması şeklinde yorumlanabilir. Aşı lojistiği süreçleri ve aşılama stratejilerine bakıldığında matematikte yer alan Zeno paradoksuna benzer bir aşı paradoksu ile karşı karşıyayız. Makalemizde tüm dünyanın karşı karşıya kaldığını düşündüğümüz “Aşı Paradoksu’ndan, nedenleri ve çözüm odaklı önerilerinden bahsedeceğiz.
Prognostic Value of Hematological Parameters in Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Authors: SOYSAL GÜNDÜZ Özgül , TORAMAN Aysun
Published: March 2022

Objective: Hematological parameters including neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), and monocyte–lymphocyte ratio (MLR) have been demonstrated as new predictors of prognosis and activity in various diseases. In this study, we aimed to investigate the associations of NLR, PLR and MLR with disease severity and prognosis in patients with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV).

Materials and Methods: Medical records of 92 AAV patients were investigated retrospectively. The clinical and laboratory data, and disease outcomes were recorded. The patients having five factor score (FFS) ≥ 2 were categorized as severe disease.

Results: 92 patients with a median age of 60 years were included. Patients with NLR≥4.8 (RR 1.83), PLR≥151.8 (RR 2.02) and MLR≥0.38 (RR 1.85) had higher risk of severe disease. In correlation analysis, NLR, PLR and MLR were positively correlated with C reactive protein and erythrocyte sedimentation rate (ESR). NLR, PLR and MLR were associated with remission.

Conclusion: Only the patients with high PLR had higher relapse rate. MLR was also correlated with development of end-stage renal disease (ESRD). Renal involvement was more frequent in patients with high levels of NLR, PLR and MLR.

Conclusions: We showed that NLR, PLR and MLR at diagnosis were associated with the severity and prognosis of AAV. This is the first study, showing the correlation of MLR with disease severity and ESRD in patients with AAV.
Yenidoğanlarda kritik konjenital kalp hastalığı tarama sonuçlarımız
Authors: TANRIVERDİ Sema , ATİK Sinem , ŞENOL Coşkun
Published: March 2022

Giriş ve Amaç: Konjenital kalp hastalığı (KKH), en sık görülen konjenital hastalıktır. Kritik konjenital kalp hastalığı (KKKH) ise, yaşamın ilk 28 gününde cerrahi operasyon ya da kateter girişimi gereksinimi olan KKH’dır. Doğumdan sonra KKKH tanısı geciken vakalarda mortalite ve morbidite artar. Bu çalışmada hastanemizde taburculuk öncesi uygulanan nabız oksimetre ile KKKH taraması sonuçlarının değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntemler: Ocak 2019 ile Ocak 2020 tarihleri arasında hastanemizde doğan ve anne yanında takip edilen 504 yenidoğan bebek çalışmaya dahil edildi. Prenatal dönemde KKKH tanısı almış ya da KKH dışı major anomalisi olan bebekler çalışmaya dahil edilmedi. Taburculuk öncesi nabız oksimetre ile preduktal ve postduktal saturasyon ölçümleri yapıldı.

Bulgular: Çalışmaya toplam 504 bebek alındı. Bebeklerin ortalama doğum haftası 38,27 ± 1,35 (35-42) hafta, doğum ağırlığı ise 3200,29 ± 476,05 (1980-4970) olarak saptandı. Kız/erkek oranı 250/254; sezeryan/normal doğum oranı 337/167 idi. Tarama sırasındaki bebeklerin ortalama yaşları 32,51 ± 17,87 (6-96) saatti. Tarama sonucu ortalama kardiak nabız 140,06 ± 15,03 (99-186) /dk, preduktal saturasyon değeri %97,66 ± 1,92 (89-100), postduktal saturasyon değeri %97,88 ± 1,84 (90-100), fark %1,49 ± 1,40 (0-7) olarak saptandı. İlk taramadan 85 (%16,9) bebek kalırken, ikinci tarama yapılan 85 bebeğin 56 (%11,1)’sı kaldı. Tarama ve fizik muayene sonrası EKO’su yapılan 72 bebeğin 45inde patoloji saptanırken 27’sinde normal olarak değerlendirildi. Hiç bir hastada KKKH saptanmadı.

Sonuç: Birçok merkezde de yapılan nabız oksimetre ile KKKH tarama sonuçlarımızı değerlendirdik. Yapılan değerlendirmede tarama testinden kalan hastaların hiçbirinde KKKH saptanmadı. Bunun da düzenli perinatal takip ve ayrıntılı ultrasonografik değerlendirmeye bağlı olduğu düşünüldü.
Yenidoğan bebeklerde hipoglisemi sıklığı ve hipoglisemiden korunmada anne sütünün önemi
Authors: TANRIVERDİ Sema
Published: March 2022

Giriş ve Amaç: Hipoglisemi, yenidoğanın en sık metabolik sorunudur ve uzun sürmesi ya da sık tekrarlaması durumunda serebral zedelenmeye neden olabilir. Bu çalışmanın amacı doğum sonrası anne yanında izlenen ve risk faktörü olan yenidoğan bebeklerde hipoglisemi sıklığını belirlemek, hipoglisemi taramasının önemini ve hipoglisemiden korunmada da anne sütünün önemini vurgulamaktır.

Gereç ve Yöntemler: Çalışmaya Mayıs 2020 ile Mayıs 2021 tarihleri arasında hastanemizde doğan ve anne yanında izlenen, risk faktörü olan yenidoğan bebekler alındı. Bebeklerde ilk kan glukozu, beslendikten 30 dakika sonra ölçüldü. Beslenme ile normoglisemik değerler elde edilmesi durumunda, ölçüm 2-3 saat aralıklarla ve beslenme öncesi olacak şekilde tekrarlandı, yaşamın 48. saatinde tarama sonlandırıldı. Hipoglisemi gelişen bebeklerle gelişmeyen bebekler demografik özellikleri, beslenme şekilleri ve kan glukoz değerleri açısındn karşılaştırıldılar.

Bulgular: Çalışmaya risk faktörü olan ve hipoglisemi taraması yapılan 260 bebek alındı. Bu bebeklerin 109’u (%41,9) preterm bebek, 62’si (%23,8) diabetik anne bebeği (DAB), 32’si (%12,3) gebelik haftasına göre büyük bebek (LGA), 10’u (%3,8) gebelik haftasına göre küçük bebek (SGA) ve 47’si (%18,1) intrauterin büyüme kısıtlılığı (İUBK) olan bebeklerdi. Yapılan taramada 260 bebeğin 24’ünde (%9,2) hipoglisemi saptandı. Bebeklerin %78,5’inde ilk beslenme anne sütüyken, sonraki beslenmelerde sadece anne sütü ile beslenen bebeklerin oranının %50,8’e düştüğü görüldü. İzlem boyunca sadece anne sütü alan bebeklerde anlamlı olarak hipogliseminin daha az olduğu görüldü (p=0,003).

Sonuç: Risk faktörü olan bebeklerin, özellikle de diabetik anne bebeklerinin doğum sonrası hipoglisemi taramalarının yapılması önemlidir. Hipoglisemi riski taşıyan bu bebeklerin, hipoglisemiden korumak için hem erken hem de geç dönemde sadece anne sütü ile beslenmeleri sağlanmalıdır.
AKUT AKCİĞER HASARI (ALI)/AKUT SOLUNUM SIKINTISI SENDROMU(ARDS) VE ARDS’Lİ COVID-19 HASTALARINDA BESLENME DESTEĞİ
Authors: YALDIZ Nihan , TÜRKER Perim
Published: March 2022

Amerika- Avrupa Konsensus Konferans Komitesi tanımına göre “akut solunum sıkıntısı sendromu”(ARDS) göğüs radyolojisinde akut başlangıçlı yaygın bilateral pulmoner infiltratlar, arteriyel oksijen/fraksiyon parsiyel basıncı (PaO2/FiO2) “akut akciğer hasarı”(ALI) için ≤300 mmHg ve ARDS için ≤200 mmHg ve pulmoner arter oklüzyon basıncı
COVID-19 Hastalarında Huzursuz Bacak Sendromunun Değerlendirilmesi
Authors: OCAK Özgül , ŞAHİN Erkan Melih
Published: March 2022

Giriş ve Amaç: COVID-19 pandemisi sürecinde birçok nörolojik hastalık yanında birlikte huzursuz bacak sendromu olan vaka bildirimleri de olmuştur. COVID-19 hastalığı uyku ve hareket bozukluğu hastalıklarına sebep olmaktadır. Çalışmamızın amacı COVID-19 polikliniğine başvuran hastalarda huzursuz bacak sendromu (HBS) sıklığını değerlendirip, COVID-19 hastalarında artma olup olmadığını belirlemektir.

Gereç ve Yöntemler: Kesitsel tanımlayıcı araştırma için COVID Polikliniğine başvuran yetişkin hastalar davet edilmiştir. Hastalara HBS tanısına yönelik soru formu doldurtulmuştur. HBS tanısı için Uluslararası HBS Çalışma Grubu tarafından hazırlanan revize tanı kriterleri kullanılmıştır.

Bulgular: 440 katılımcıdan 232’si erkek, 208’i kadındı. Başvuruları herhangi bir şikayete dayalı olan 301 hastadan 33’ünde (%11,0) HBS bulunduğu değerlendirildi. HBS oranları RT-PCR test sonucu açısından anlamlı farklı değildi.

Sonuç: COVID-19 hastalığında HBS vaka bildirimleri yapılmış olmasına rağmen geniş prospektif çalışma bulunmamaktadır. Bu çalışmada COVID-19 polikinik başvurularında HBS olan hastalar saptamamıza rağmen HBS sıklığının RT-PCR testi ile COVID-19 olduğu gösterilen hastalarda farklı olmadığını bulduk. Bu sonuç viral üst solunum yolu enfeksiyonları ile birlikte ortaya çıkabilen HBS şikayetlerinin COVID-19’a özgü özellik göstermediğini şeklinde yorumlanmıştır.
The Oktober Flut: An anomalous extreme high-water event in Annapolis, MD, USA, October 2021
Authors: Velásquez-Montoya Liliana , Davies Alexander , Guth Peter , Tomiczek Tori , Laun Alexander , Wargula Anna , Henderson Gina , Steppe Cecily , Wallendorf Louise
Published: March 2022

Between 28 and 30 October 2021, Annapolis, Maryland, USA, experienced the third highest flood event on record, referred to as the “Oktober Flut.” Unlike many of the extreme coastal flood events that have impacted Annapolis in the past, the Oktober Flut was not associated with a tropical or post-tropical cyclone. Instead, sustained wind forcing from a series of passing extratropical storms drove anomalously high water levels. The maximum observed hourly water level during the event was 4.88 ft above mean lower low water (MLLW). This exceeded the Moderate Flood Stage, defined by the National Weather Service (NWS) as 3.3 ft (MLLW), and had an annual exceedance probability of 5.2%. In total, flood waters exceeded the NWS Minor Flood Stage (2.6 ft MLLW) for 78 non-consecutive hours over multiple tidal periods. Relative sea level rise and increasing instances of coastal nuisance flooding events, like the Oktober Flut, have the potential to impact the local economy in Annapolis, MD, and operations at the geographically adjacent U.S. Naval Academy. Coastal nuisance flooding events also challenge existing community resilience efforts and initiatives, particularly those related to preparing for natural hazards. This paper provides an overview of the meteorological factors that drove the anomalously high-water levels and coastal flooding at the U.S. Naval Academy. In addition to data analysis from fixed, long-term sensors maintained by federal partners, observations from spotdeployments in advance of the storm are also presented. The results are discussed with respect to the storm impacts on infrastructure and facility preparedness. Lessons learned are documented with the aim of informing other coastal communities on how to better assess local flood-specific action plans, based on the accuracy and timing of forecast data.
Divine Works of Thirumuruga Kirubhanandha Vaariyaar
Authors: B Chitradevi
Published: March 2022

Samiyanna, a Shiva devotee, lived in the steep Veera Saiva tradition in Kangeyanallur. His life partner is Tanjammal. Mallya was born as their fourth son. He was popularly known as Mallayadasar as he traveled from village to village. Mallyadasar - Kanakavalli Ammaiyar couple have eleven children. A baby boy was born on Friday, the ninth day of Document Monday. He is the warrior of Thirumuruga Kripananda. Born with a womb in the womb, the warrior was well-educated enough to pick up texts and read them when he was five years old. At the age of eight Venpaa became a singing power. He started composing songs like Virutham as he had the energy to sing hard venpa. By the age of ten he had memorized ten thousand songs. The best Murugan devotee. He lived a life of penance, performing daily spiritual discourses. He is a profound scholar in many fields such as religion, literature, oratory, writing and music. At the age of nineteen he married Amirthalakshmi, the daughter of his maternal uncle Sivaguru Mudaliar. He was very attached to Arunagirinath. The music with Iyal was taught to the warrior by his father. His father was the guru of Tamil grammar, Thevaram, Thiruvasakam, Tirupugal, historical hymns etc. Chief Minister Palanisamy has announced that his birthday will be celebrated as a state festival from 2021. The purpose of this article is to examine his religious work.
Techniques for Cognitive Pathways from Natrinai
Authors: R Geetha
Published: March 2022

Man changes the world only through actions and therefore changes himself. His power is manifested in the actions of man. Man is created by labor and action. During the Sangam period, farming was hailed as a life-saving profession. Livestock were used for needs beyond human capacity. The need of the individual is the need of the society in which he lives. It is on this basis that every business flourishes and benefits. Through this study we can know how the Tamils ​​planned and carried out their careers through the hymns in the Sangam literature.
Story Begins in Jayamohan’s Virtue Short Story Collection
Authors: S Saranya
Published: March 2022

Story telling and listening to stories is happening in the tamil community. It was given the form of a short story. The beginning of a good short story is artistic and charismatic enough inspire readers to read. The short series that deals with the introduction of the story mantra in the form of dialogue in the form of narrative statement stage start conscious awareness brings the character to the forefront and enlivens the stories so the beginning of the short stories Jayamohan’s short stories are set in the middle of the story in away that provokes problems and curiosity.
Aesthetics in Ilandevan Poems
Authors: P Theertharaman , A Siluvaimuthu
Published: March 2022

Aesthetics is the ability to explore aesthetics, to explore the race of beauty in works of art, and to create works with taste. In Tolkappiyam, the oldest grammar book in the Tamil language, both rhetoric and allegory are said to be aesthetically pleasing.  The poet also gives shape to his thought. This is what we call aesthetics, which lines the imagination and injects aesthetic elements into the poem. Poet ILandevan, who is good at writing poetry with aesthetic and aesthetic elements, has used aesthetic elements in his poetry collection to strengthen his language, technique, form and thought. he has used the moon, the sky, and the milky way galaxy as his objects of natural expression.
Father and Son Obligation in Tamil literature
Authors: K Kumarakurubaran
Published: March 2022

Every human being lives with some restraint appropriate to the social system. The primary duty of a good father is to make his son excellent in education. This is the duty of the son to the father. The reason why human society is improving is because of the unexpected. The act of teaching the father to live his life better with the control of the individual becomes paramount. Duty is like a chain within the family. Wherever the food chain of nature is harvested, the impact will be on mankind. Similarly, man's violation of his duty will affect human society. This article is designed to show that Tamil literature has recorded the duty of the son and father in a special way over time.
History and Culture of the Papanasa Kaani People in Anthropological Perspective
Authors: A.S Raja
Published: March 2022

The aim of the paper is to know the history, culture and tradition of the ancient kani people. The methodolgyis to collect the materials orally and taking personal interviews. the place is located in Tenkasi district, Ambasamudrum and pabanasam areas. In ancient days kani people used eat animals honey and Tuber and bulbs but now they eat rice and grains. They are living in huts. They are planting medicinal plants and one famous pharmacy is there. For centuries they have been giving medicine for jaundice. They are worshipping Goddess like petchiamman. They also built a church for Christian congregation.They prefer love marriages. divorce and remarriage are allowed and acceptable.
Representation of Dalit life in Imaiyam's Koveru Kazhuthaigal
Authors: K Abilasha
Published: March 2022

Indian society and its collective consciousness are polluted with casteism. After thousands of years of suppression and exploitation, the margin came to the centre and the other side of the history was revealed. Dalit literature gave insights about the dalit life which otherwise is never written in a dalit’s view. “Writing about Dalits by Dalit writers with a Dalit Consciousness” says Sharan Kumar Limbale about Dalit literature in his book Towards an Aesthetic of Dalit Literature. Having this as base, this paper proposes to study Imaiyam's Koveru Kazhuthaigal from dalit literary perspective and appreciate the life represented in it. The novel is set in an Indian village and the protagonists belong to the washerman community which is considered as the lowest of the lower in caste hierarchy practiced in Tamilnadu. The hypothesis is to question the collective consciousness regarding the inhuman casteist practices and demand change in the life of the oppressed and in the conscience of the oppressor. Famous Tamil Dalit writer Bama proposes eduation as a solution for casteism in her semi autobiographial text Karukku; Imaiyam shows change of place from rural to urban setup as a solution for better treatment. The real solution demands change from the oppressor too. Limitations of this research is the huge volume of the possible solution to the problem represented and the concrete presence of casteism in Indian psyche.
The Devotional Norm of the Siddharthas
Authors: T Thakshna Moorthy
Published: March 2022

This is the time when the Tamil community is being studied globally. The reason is that the multi-purpose talents of the Tamils ​​who have lived in every age are astonishing to many. These skills have been documented in the literature over time. One of them is Siddharth literature. It is no exaggeration to say that the Siddhars who originated in the Tamil tradition have a unique place in India and in the world. Those who have attained the eight types of Siddhas are generally called Siddhas. The Siddhas realized the instability of the yajna and subjected their body to their enlightenment, knowing the way to live with their body without dying for a long time. Needless to say, there is no such thing as a field that the Siddhars who have lived for a long time have not studied. Atheists have the argument that atheists are supernaturalists. Some may have defined themselves as atheists because they hate idolatry and say it in their songs. This article is designed to illustrate the point that the Siddhas are of the opinion that they should have a united mind and worship by removing the hypocrisy of paganism and how they have visualized the forms of the Lord in their songs.
Social Reconciliation Domains in Poomani's Agnaadi
Authors: P Sudhasankari , I Petchimuthu
Published: March 2022

His family is a full-time farmer. If only he was good enough and everyone wants to be good. That is why he became accustomed to social harmony with everyone, regardless of caste, religion or race. Agnaadi novelist Boomani has pointed out with various evidences of the harmony he has manifested in various evolutions, such as helping others in times of distress, speaking comfortingly and being with them. Andy's concern for his surviving friend Vannan Gudi, Marie, and his family, as well as his assistance to the Nadar people, speaks volumes that he is a social peace activist. The harmony he has with the Parakudi Sanas is as great as the harmony he has over the Nadar and Nayakar castes. Man, not only symbolizes how to love man but also sets an example for future generations the upper castes will speak proudly of Andy's seed. They say he inquires about crop yields just as they inquire about spots. This article describes Andy's professional harmony with this aristocrat.
A Study of Marxist Literary Theories and the Novel Surangam in a Socialist Realist Way
Authors: R Kumaraguruparan
Published: March 2022

What led Prof Prabhat Patnaik, Pope at Vatican City and Dr Raghuram Rajan to a rallying point for the recovery and sustainability of the Global Capitalism from its shivering crisis? It's Karl Marx's 'Capital' ('Das Kapital'). Literature Review of Miners' plight in Indian Literature. World's top ten mine disasters in which two happened in India - Dhanbad and Chasnala. ' Kaala Pathar' Hindi film was based on Chasnala mining disaster. Nationalisation of Indian Coal Industry thanks to Indian coal miners' continuous struggles. Introduction of Ku.Chinnappa Bharathi, Tamil writer, who authored  'Surangam' Tamil novel. How did the idea of writing 'Surangam' come to Ku. Chinnappa Bharathi's mind? Shri Bikas Chowdhury, CPI-M MP from Asansol Constituency, invited the writer to pay a visit to Dhanbad, Jharia and  Asansol mines, to study the plight and living standards of the workers to attempt a novel on this theme. KuChiBha. accepted the offer. The conversation with the miners with the help of interpreters, contributed a lot to visualize the air. Plot of Surangam. The category of workers and the hierarchy of supervisors. Bikas Choudhary, Jamuna Kumari, Sakuntala Devi, Mining Munshi, Mining Sardar, Mine owner Tiwari, organised workers, drunkard-workers, Debt recovery agents, liquor shop-owner, villagers, peasants and the like. The greed of inhuman mine-owners and supervisors is portrayed the customs and cultural events of Bengalis and the tenets of  humanitarian Marxist Atheism are briefed. How the novel observes the genre of Socialist Realism, with the Marxist point of view, is well-presented. The denationalisation of the Coal Industry, with the repeal of Mining Nationalisation Acts, will again unleash the exploitation of private owners in the coal industry. The case-study of  ' Surangam ' to explore the livelihood of the miners in non-Tamil speaking areas to write a novel in Tamil, for being translated further into Bengali and Hindi, is a laudable attempt and a great literary venture.