bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Nanocoating on the Performance of Photovoltaic Solar Panels in Al Seeb, Oman
Authors: Chala Girma T. , Sulaiman Shaharin A. , Chen Xuecheng , Al Shamsi Salim S.
Published: June 2024

Solar photovoltaic (PV) panels are projected to become the largest contributor of clean electricity generation worldwide. Maintenance and cleaning strategies are crucial for optimizing solar PV operations, ensuring a satisfactory economic return of investment. Nanocoating may have potential for optimizing PV operations; however, there is insufficient scientific evidence that supports this idea. Therefore, this study aims to investigate the effectiveness of nanocoating on the performance of solar photovoltaic (PV) panels installed in Al Seeb, Oman. A further study was also carried out to observe the influence of coating layers on the performance of PV panels. One SiO2 nanocoated solar panel, another regularly cleaned PV panel, and a reference uncleaned panel were used to carry out the study. The site of the study was treeless and sandy, with a hot and dry climate. A data logger was connected to the solar PV panel and glass panel to record the resulting voltage, current, temperature, and solar radiation. It was observed that nanocoated PV panels outperformed both regular PV panels and uncleaned PV panels. Nanocoated PV panels demonstrated an average efficiency of 21.6%, showing a 31.7% improvement over uncleaned panels and a 9.6% improvement over regularly cleaned panels. Although nanocoating displayed high efficiency, regular cleaning also contributes positively. Furthermore, even though nanocoated PV panels outperformed the other two panels, it is important to note that the performance difference between the regular cleaned PV panels and the nanocoated PV panels was small. This indicates that regular cleaning strategies and nanocoating can further contribute to maintaining a more efficient solar PV system. Coating in many layers was also observed to influence the performance of PV panels insignificantly, mainly the fourth layer coating appeared to have formed sufficient mass to retain heat.
Electrical Vehicle Smart Charging Using the Open Charge Point Interface (OCPI) Protocol
Authors: Guillemin Sylvain , Choulet Romain , Guyot Gregory , Hing Sothun
Published: June 2024

This paper proposes a new approach to the design of smart charging systems. It aims to separate the role of the Smart Charging Service Provider (SCSP) from the role of the Charge Point Operator (CPO) to provide real flexibility and efficiency of mass deployment. As interoperability is required for this purpose, the challenge is to use standard equipment and protocols in the design of the smart charging Energy Management System (EMS). The use of an Open Charge Point Interface (OCPI) is crucial for an interface between the EMS and the Charge Point Operator. The smart charging EMS developed has been implemented and successfully tested with two CPOs, with different use cases: (1) EV charging infrastructure at office buildings, and (2) EV charging infrastructure installed at a public car park facility.
The Dynamics of Energy-Related Carbon Emissions and Their Influencing Factors in the Yangtze River Delta, China
Authors: Li Xiang’er , Gong Jiajun , Ni Xuan , Zheng Zhiyi , Zhao Qingshan , Hu Yi’na
Published: June 2024

Chinese cities are pursuing an energy transition to decouple energy-related carbon emissions (ERCEs) from economic growth. Despite numerous studies focusing on the factors influencing carbon emissions, few have quantitatively analyzed their respective contribution rates, thus leaving a gap in effectively guiding policies. This study took 16 cities in the Yangtze River Delta (YRD) as the study area. The decoupling between ERCEs and economic growth was analyzed during 2000–2020, and the contribution rates of different factors were explored. The results showed that the total ERCEs increased from 413.40 million to 1265.86 million tons during 2000–2020, increasing by over three times. Coal and oil were the dominant energy sources in most cities, but natural gas consumption increased from 0.15% to 5.96%. Moreover, 14 cities showed a decoupling status, indicating a certain win–win situation between economic growth and ERCE reduction. Economic growth greatly increased ERCEs, with its contribution rate ranging from 114.65% to 493.27% during 2000–2020. On the contrary, energy structure and energy intensity both contributed to reducing ERCEs in most cities, and their maximum contribution rates reached −32.29% and −449.13%, respectively, which were the main forces for the win–win situation. Finally, carbon reduction proposals are put forward, which provide theoretical support for achieving the “Double Carbon” goal in the YRD.
Efficient Operationalization of Flexibility Procurement: Market Design Analysis and Process Definition
Authors: Fanta Sarah , Tolstrup Ksenia , Riegler Markus , Obernosterer Lukas , Wirrer Christina
Published: June 2024

Flexibility provision for ancillary services and electricity markets has been widely seen as crucial for the future of highly interconnected energy systems with high shares of renewables. Yet, little research has so far addressed (1) how its procurement could be best operationalized and (2) how limited flexible resources can be used more efficiently given the growing system needs. This paper focuses on flexibility services for transmission operators, specifically balancing and redispatch, as well as the intraday market within the context of the European electricity market. To analyze possible services and/or market combinations, we compare three modes of flexibility procurement: (a) sequential, (b) parallel and (c) combined. We evaluate the different modes of procurement options based on eight criteria. We further investigate how the procurement of flexibility, including small-scale technical units, could be organized via a flexibility platform given the most promising implementation setup, and detail the process for “flexibility service provider <> flexibility platform <> market interaction”, taking the multi-use-case logic into account.
Fish Bones as Calcium Source: Bioavailability of Micro and Nano Particles
Authors: Torres Benjamín , Pérez Alvaro , García Paula , Jiménez Paula , Abrigo Karen , Valencia Pedro , Ramírez Cristian , Pinto Marlene , Almonacid Sergio , Ruz Manuel
Published: June 2024

The amount of by-products/waste in the fish industry is roughly 50%. Fish bones could be used to produce nanoparticles, which may have potential use in the food industry as a novel calcium source and at the same time, contribute to reduce waste production. The objective of this study was to evaluate the bioavailability of nano-size salmon fish bone particles compared to micro-size salmon fish bone particles, and calcium carbonate. The study was carried out in 21–28-day-old C57BL/6 male mice fed for 21 days with the experimental diets. The groups were as follows: CaCO3 0.5% Ca (CN 0.5); CaCO3 1.0% Ca (CN 1.0); salmon fish bone (SFB) microparticles 0.5% Ca (MP 0.5); SFB microparticles 1.0% Ca (MP 1.0); SFB nanoparticles 0.5% Ca (NP 0.5); and SFB nanoparticles 1.0% Ca (NP 1.0). Calcium bioavailability, defined as the percent calcium in femur showed an increasing trend from CN 0.5 to NP 1.0 group. According to ANCOVA, the greatest Ca content was observed in the NP 1.0 group compared with all groups but NP 0.5. In conclusion, in a murine model, salmon fish bone nanoparticles present higher calcium bioavailability than salmon fish bone microparticles, and both, in turn, have better bioavailability than calcium carbonate.
Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review
Authors: Lucarini Alessio , Arrivi Giulia , Liotta Elena , Li Causi Francesco Saverio , Di Cicco Leonardo , Mazzuca Federica , Osti Mattia Falchetto , Balducci Genoveffa , Mercantini Paolo
Published: June 2024

Leptomeningeal carcinomatosis (LC) is a rare site of metastasis in solid tumors, and it is associated with poor prognosis due to disabling symptoms and a scarcity of treatment options. This condition is an uncommon entity in gastric cancer (GC). We present a case of primary LC manifestation in a patient with an incidental diagnosis of localized node-negative GC. We additionally perform a literature review and discuss the diagnostic and therapeutic challenges. In conclusion, LC from GC represents a rare condition with a dramatic prognosis. Its diagnosis might be very challenging. A multidisciplinary approach appears to be the best strategy for the management of LC from GC.
Mizoribine Promotes Molecular Chaperone HSP60/HSP10 Complex Formation
Authors: Miura Atsuko , Narita Yukihiko , Sugawara Taku , Shimizu Hiroaki , Itoh Hideaki
Published: June 2024

It has been reported that Mizoribine is an immunosuppressant used to suppress rejection in renal transplantation, nephrotic syndrome, lupus nephritis, and rheumatoid arthritis. The molecular chaperone HSP60 alone induces inflammatory cytokine IL-6 and the co-chaperone HSP10 alone inhibits IL-6 induction. HSP60 and HSP10 form a complex in the presence of ATP. We analyzed the effects of Mizoribine, which is structurally similar to ATP, on the structure and physiological functions of HSP60–HSP10 using Native/PAGE and transmission electron microscopy. At low concentrations of Mizoribine, no complex formation of HSP60–HSP10 was observed, nor was the expression of IL-6 affected. On the other hand, high concentrations of Mizoribine promoted HSP60–HSP10 complex formation and consequently suppressed IL-6 expression. Here, we propose a novel mechanism of immunosuppressive action of Mizoribine.
Testing the Simplified Molecular Dynamics Approach to Improve the Reproduction of ECD Spectra and Monitor Aggregation
Authors: Mándi Attila , Rimóczi Aliz , Vasas Andrea , Hohmann Judit , Swamy Mahadeva M. M. , Monde Kenji , Barta Roland A. , Kicsák Máté , Komáromi István , Fehér Krisztina , Kurtán Tibor
Published: June 2024

A simplified molecular-dynamics-based electronic circular dichroism (ECD) approach was tested on three condensed derivatives with limited conformational flexibility and an isochroman-2H-chromene hybrid, the ECD spectra of which could not be precisely reproduced by the conventional ECD calculation protocol. Application of explicit solvent molecules at the molecular mechanics (MD) level in the dynamics simulations and subsequent TDDFT-ECD calculation for the unoptimized MD structures was able to improve the agreements between experimental and computed spectra. Since enhancements were achieved even for molecules with limited conformational flexibility, deformations caused by the solvent molecules and multitudes of conformers produced with unoptimized geometries seem to be key factors for better agreement. The MD approach could confirm that aggregation of the phenanthrene natural product luzulin A had a significant contribution to a specific wavelength range of the experimental ECD. The MD approach has proved that dimer formation occurred in solution and this was responsible for the anomalous ECD spectrum. The scope and limitations of the method have also been discussed.
Analysis of Arc/Arg3.1 Oligomerization In Vitro and in Living Cells
Authors: Barylko Barbara , Taylor Clinton A. , Wang Jason , Hedde Per Niklas , Chen Yan , Hur Kwang-Ho , Binns Derk D. , Brautigam Chad A. , DeMartino George N. , Mueller Joachim D. , Jameson David M. , Albanesi Joseph P.
Published: June 2024

Arc (also known as Arg3.1) is an activity-dependent immediate early gene product enriched in neuronal dendrites. Arc plays essential roles in long-term potentiation, long-term depression, and synaptic scaling. Although its mechanisms of action in these forms of synaptic plasticity are not completely well established, the activities of Arc include the remodeling of the actin cytoskeleton, the facilitation of AMPA receptor (AMPAR) endocytosis, and the regulation of the transcription of AMPAR subunits. In addition, Arc has sequence and structural similarity to retroviral Gag proteins and self-associates into virus-like particles that encapsulate mRNA and perhaps other cargo for intercellular transport. Each of these activities is likely to be influenced by Arc’s reversible self-association into multiple oligomeric species. Here, we used mass photometry to show that Arc exists predominantly as monomers, dimers, and trimers at approximately 20 nM concentration in vitro. Fluorescence fluctuation spectroscopy revealed that Arc is almost exclusively present as low-order (monomer to tetramer) oligomers in the cytoplasm of living cells, over a 200 nM to 5 μM concentration range. We also confirmed that an α-helical segment in the N-terminal domain contains essential determinants of Arc’s self-association.
The Lung in Rheumatoid Arthritis—Friend or Enemy?
Authors: Anton Maria-Luciana , Cardoneanu Anca , Burlui Alexandra Maria , Mihai Ioana Ruxandra , Richter Patricia , Bratoiu Ioana , Macovei Luana Andreea , Rezus Elena
Published: June 2024

Rheumatoid arthritis (RA) is a chronic autoimmune condition frequently found in rheumatological patients that sometimes raises diagnosis and management problems. The pathogenesis of the disease is complex and involves the activation of many cells and intracellular signaling pathways, ultimately leading to the activation of the innate and acquired immune system and producing extensive tissue damage. Along with joint involvement, RA can have numerous extra-articular manifestations (EAMs), among which lung damage, especially interstitial lung disease (ILD), negatively influences the evolution and survival of these patients. Although there are more and more RA-ILD cases, the pathogenesis is incompletely understood. In terms of genetic predisposition, external environmental factors act and subsequently determine the activation of immune system cells such as macrophages, neutrophils, B and T lymphocytes, fibroblasts, and dendritic cells. These, in turn, show the ability to secrete molecules with a proinflammatory role (cytokines, chemokines, growth factors) that will produce important visceral injuries, including pulmonary changes. Currently, there is new evidence that supports the initiation of the systemic immune response at the level of pulmonary mucosa where the citrullination process occurs, whereby the autoantibodies subsequently migrate from the lung to the synovial membrane. The aim of this paper is to provide current data regarding the pathogenesis of RA-associated ILD, starting from environmental triggers and reaching the cellular, humoral, and molecular changes involved in the onset of the disease.
Maternal Hypermethylated Genes Contribute to Intrauterine Growth Retardation of Piglets in Rongchang Pigs
Authors: Wu Pingxian , Wang Junge , Ji Xiang , Chai Jie , Chen Li , Zhang Tinghuan , Long Xi , Tu Zhi , Chen Siqing , Zhang Lijuan , Wang Ketian , Zhang Liang , Guo Zongyi , Wang Jinyong
Published: June 2024

The placenta is a crucial determinant of fetal survival, growth, and development. Deficiency in placental development directly causes intrauterine growth retardation (IUGR). IUGR can lead to fetal growth restriction and an increase in the mortality rate. The genetic mechanisms underlying IUGR development, however, remain unclear. In the present study, we integrated whole-genome DNA methylation and transcriptomic analyses to determine distinct gene expression patterns in various placental tissues to identify pivotal genes that are implicated with IUGR development. By performing RNA-sequencing analysis, 1487 differentially expressed genes (DEGs), with 737 upregulated and 750 downregulated genes, were identified in IUGR pigs (H_IUGR) compared with that in normal birth weight pigs (N_IUGR) (p < 0.05); furthermore, 77 miRNAs, 1331 lncRNAs, and 61 circRNAs were differentially expressed. The protein–protein interaction network analysis revealed that among these DEGs, the genes GNGT1, ANXA1, and CDC20 related to cellular developmental processes and blood vessel development were the key genes associated with the development of IUGR. A total of 495,870 differentially methylated regions were identified between the N_IUGR and H_IUGR groups, which included 25,053 differentially methylated genes (DMEs); moreover, the overall methylation level was higher in the H_IUGR group than in the N_IUGR group. Combined analysis showed an inverse correlation between methylation levels and gene expression. A total of 1375 genes involved in developmental processes, tissue development, and immune system regulation exhibited methylation differences in gene expression levels in the promoter regions and gene ontology regions. Five genes, namely, ANXA1, ADM, NRP2, SHH, and SMAD1, with high methylation levels were identified as potential contributors to IUGR development. These findings provide valuable insights that DNA methylation plays a crucial role in the epigenetic regulation of gene expression and mammalian development and that DNA-hypermethylated genes contribute to IUGR development in Rongchang pigs.
Imaging Flow Cytometry and Convolutional Neural Network-Based Classification Enable Discrimination of Hematopoietic and Leukemic Stem Cells in Acute Myeloid Leukemia
Authors: Hybel Trine Engelbrecht , Jensen Sofie Hesselberg , Rodrigues Matthew A. , Hybel Thomas Engelbrecht , Pedersen Maya Nautrup , Qvick Signe Håkansson , Enemark Marie Hairing , Bill Marie , Rosenberg Carina Agerbo , Ludvigsen Maja
Published: June 2024

Acute myeloid leukemia (AML) is a heterogenous blood cancer with a dismal prognosis. It emanates from leukemic stem cells (LSCs) arising from the genetic transformation of hematopoietic stem cells (HSCs). LSCs hold prognostic value, but their molecular and immunophenotypic heterogeneity poses challenges: there is no single marker for identifying all LSCs across AML samples. We hypothesized that imaging flow cytometry (IFC) paired with artificial intelligence-driven image analysis could visually distinguish LSCs from HSCs based solely on morphology. Initially, a seven-color IFC panel was employed to immunophenotypically identify LSCs and HSCs in bone marrow samples from five AML patients and ten healthy donors, respectively. Next, we developed convolutional neural network (CNN) models for HSC-LSC discrimination using brightfield (BF), side scatter (SSC), and DNA images. Classification using only BF images achieved 86.96% accuracy, indicating significant morphological differences. Accuracy increased to 93.42% when combining BF with DNA images, highlighting differences in nuclear morphology, although DNA images alone were inadequate for accurate HSC-LSC discrimination. Model development using SSC images revealed minor granularity differences. Performance metrics varied substantially between AML patients, indicating considerable morphologic variations among LSCs. Overall, we demonstrate proof-of-concept results for accurate CNN-based HSC-LSC differentiation, instigating the development of a novel technique within AML monitoring.
Deciphering Early and Progressive Molecular Signatures in Alzheimer’s Disease through Integrated Longitudinal Proteomic and Pathway Analysis in a Rodent Model
Authors: Yadikar Hamad , Ansari Mubeen A. , Abu-Farha Mohamed , Joseph Shibu , Thomas Betty T. , Al-Mulla Fahd
Published: June 2024

Alzheimer’s disease (AD), the leading cause of dementia worldwide, remains a challenge due to its complex origin and degenerative character. The need for accurate biomarkers and treatment targets hinders early identification and intervention. To fill this gap, we used a novel longitudinal proteome methodology to examine the temporal development of molecular alterations in the cortex of an intracerebroventricular streptozotocin (ICV-STZ)-induced AD mouse model for disease initiation and progression at one, three-, and six-weeks post-treatment. Week 1 revealed metabolic protein downregulation, such as Aldoa and Pgk1. Week 3 showed increased Synapsin-1, and week 6 showed cytoskeletal protein alterations like Vimentin. The biological pathways, upstream regulators, and functional effects of proteome alterations were dissected using advanced bioinformatics methods, including Ingenuity Pathway Analysis (IPA) and machine learning algorithms. We identified Mitochondrial Dysfunction, Synaptic Vesicle Pathway, and Neuroinflammation Signaling as disease-causing pathways. Huntington’s Disease Signaling and Synaptogenesis Signaling were stimulated while Glutamate Receptor and Calcium Signaling were repressed. IPA also found molecular connections between PPARGC1B and AGT, which are involved in myelination and possible neoplastic processes, and MTOR and AR, which imply mechanistic involvements beyond neurodegeneration. These results help us comprehend AD’s molecular foundation and demonstrate the promise of focused proteomic techniques to uncover new biomarkers and therapeutic targets for AD, enabling personalized medicine.
Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread
Authors: Cuffaro Francesca , Russo Edda , Amedei Amedeo
Published: June 2024

Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects around 10% of reproductive-age women, significantly affecting fertility. Its prevalence remains elusive due to the surgical confirmation needed for diagnosis. Manifesting with a range of symptoms, including dysmenorrhea, dyschezia, dysuria, dyspareunia, fatigue, and gastrointestinal discomfort, EM significantly impairs quality of life due to severe chronic pelvic pain (CPP). Psychological manifestations, notably depression and anxiety, frequently accompany the physical symptoms, with CPP serving as a key mediator. Pain stems from endometrial lesions, involving oxidative stress, neuroinflammation, angiogenesis, and sensitization processes. Microbial dysbiosis appears to be crucial in the inflammatory mechanisms underlying EM and associated CPP, as well as psychological symptoms. In this scenario, dietary interventions and nutritional supplements could help manage EM symptoms by targeting inflammation, oxidative stress, and the microbiome. Our manuscript starts by delving into the complex relationship between EM pain and psychological comorbidities. It subsequently addresses the emerging roles of the microbiome, inflammation, and oxidative stress as common links among these abovementioned conditions. Furthermore, the review explores how dietary and nutritional interventions may influence the composition and function of the microbiome, reduce inflammation and oxidative stress, alleviate pain, and potentially affect EM-associated psychological disorders.
Integrating Transcriptomics and Proteomics to Characterize the Intestinal Responses to Cadmium Exposure Using a Piglet Model
Authors: Li Yikun , Pan Yiling , Yin Yulong , Huang Ruilin
Published: June 2024

Cadmium (Cd) is a heavy metal element with a wide range of hazards and severe biotoxicity. Since Cd can be easily accumulated in the edible parts of plants, the exposure of humans to Cd is mainly through the intake of Cd-contaminated food. However, the intestinal responses to Cd exposure are not completely characterized. Herein, we simulated laboratory and environmental Cd exposure by feeding the piglets with CdCl2-added rice and Cd-contaminated rice (Cdcr) contained diet, as piglets show anatomical and physiological similarities to humans. Subsequent analysis of the metal element concentrations showed that exposure to the two types of Cd significantly increased Cd levels in piglets. After verifying the expression of major Cd transporters by Western blots, multi-omics further expanded the possible transporters of Cd and found Cd exposure causes wide alterations in the metabolism of piglets. Of significance, CdCl2 and Cdcr exhibited different body distribution and metabolic rewiring, and Cdcr had stronger carcinogenic and diabetes-inducing potential. Together, our results indicate that CdCl2 had a significant difference compared with Cdcr, which has important implications for a more intense study of Cd toxicity.
Optimization of Liquid Crystalline Mixtures Enantioseparation on Polysaccharide-Based Chiral Stationary Phases by Reversed-Phase Chiral Liquid Chromatography
Authors: Urbańska Magdalena
Published: June 2024

Enantioseparation of nineteen liquid crystalline racemic mixtures obtained based on (R,S)-2-octanol was studied in reversed-phase mode on an amylose tris(3-chloro-5-methylphenylcarbamate) (ReproSil Chiral-MIG) and a cellulose tris(3,5-dichlorophenylcarbamate) (ReproSil Chiral-MIC). These polysaccharide-based chiral stationary phase (CSP) columns for High-Performance Liquid Chromatography (HPLC) were highly effective in recognizing isomers of minor structural differences. The mobile phase (MP), which consists of acetonitrile (ACN)/water (H2O) at different volume ratios, was used. The mobile phases were pumped at a flow rate of 0.3, 0.5, or 1 mL·min−1 with a column temperature of 25 °C, using a UV detector at 254 nm. The order of the elution was also determined. The chromatographic parameters, such as resolution (Rs), selectivity (α), and the number of theoretical plates, i.e., column efficiency (N), were determined. The polysaccharide-based CSP columns have unique advantages in separation technology, and this study has shown the potential usefulness of the CSP columns in separating liquid crystalline racemic mixtures belonging to the same homologous series.
Evaluating Single-Nucleotide Polymorphisms in Inflammasome Proteins and Serum Levels of IL-18 and IL-1β in Kidney Interstitial Damage in Anti-Neutrophilic Cytoplasmic Antibody-Associated Vasculitis
Authors: Martinez Valenzuela Laura , Vidal-Alabró Anna , Rubio Belén , Antón-Pàmpols Paula , Gómez-Preciado Francisco , Fulladosa Xavier , Cruzado Josep Maria , Torras Juan , Lloberas Nuria , Draibe Juliana
Published: June 2024

The inflammasome regulates the innate inflammatory response and is involved in autoimmune diseases. In this study, we explored the levels of IL-18 and IL-1β in serum and urine and the influence of various single-nucleotide polymorphisms (SNPs) on kidney lesions at diagnosis in patients with ANCA-associated vasculitis (AAV) and their clinical outcomes. Ninety-two patients with renal AAV were recruited, and blood and urine were collected at diagnosis. Serum and urine cytokine levels were measured by ELISA. DNA was extracted and genotyped using TaqMan assays for SNPs in several inflammasome genes. Lower serum IL-18 (p = 0.049) and the IL-18 rs187238 G-carrier genotype (p = 0.042) were associated with severe fibrosis. The IL-18 rs1946518 TT genotype was associated with an increased risk of relapse (p = 0.05), whereas GG was related to better renal outcomes (p = 0.031). The rs187238 GG genotype was identified as a risk factor for mortality within the first year after AAV diagnosis, independent of the requirement for dialysis or lung involvement (p = 0.013). We suggest that decreased cytokine levels could be a surrogate marker of scarring and chronicity of the renal lesions, together with the rs187238 GG genotype. If our results are validated, the rs1946518 TT genotype predicts the risk of relapse and renal outcomes during follow-up.
CuFe2O4 Nanofiber Incorporated with a Three-Dimensional Graphene Sheet Composite Electrode for Supercapacitor and Electrochemical Sensor Application
Authors: Vinothini Sivaramakrishnan , Keyan Arjunan Karthi , Sakthinathan Subramanian , Chiu Te-Wei , Vittayakorn Naratip
Published: June 2024

The demand for regenerative energy and electric automotive applications has grown in recent decades. Supercapacitors have multiple applications in consumer alternative electronic products due to their excellent energy density, rapid charge/discharge time, and safety. CuFe2O4-incorporated three-dimensional graphene sheet (3DGS) nanocomposites were studied by different characterization studies such as X-ray diffraction, transmission electron microscopy, and scanning electron microscopy. The electrochemical studies were based on cyclic voltammetry (CV), galvanostatic charge–discharge (GCD), and electrochemical impedance spectroscopy (EIS) measurements. As prepared, 3DGS/CuFe2O4 nanocomposites exhibited an excellent surface area, high energy storage with appreciable durability, and excellent electrocatalysis properties. A supercapacitor with 3DGS/CuFe2O4-coated nickel foam (NF) electrodes exhibited an excellent specific capacitance of 488.98 Fg−1, a higher current density, as well as a higher power density. After charge–discharge cycles in a 2.0 M KOH aqueous electrolyte solution, the 3DGS/CuFe2O4/NF electrodes exhibited an outstanding cyclic stability of roughly 95% at 10 Ag−1, indicating that the prepared nanocomposites could have the potential for energy storage applications. Moreover, the 3DGS/CuFe2O4 electrode exhibited an excellent electrochemical detection of chloramphenicol with a detection limit of 0.5 µM, linear range of 5–400 µM, and electrode sensitivity of 3.7478 µA µM−1 cm−2.
Pursuing Optimization Using Multimodal Transportation System: A Strategic Approach to Minimizing Costs and CO2 Emissions
Authors: Derpich Ivan , Duran Claudia , Carrasco Raul , Moreno Fabricio , Fernandez-Campusano Christian , Espinosa-Leal Leonardo
Published: June 2024

The core problem of a multimodal transportation system is integrating various transportation modes into a cohesive, efficient, and user-friendly network. This study introduces a novel centralized load concentration approach for regions facing geographic challenges. The principal aim is improving multimodal transportation systems by mitigating CO2 emissions and improving operational efficiency. This will significantly reduce high logistics costs and the environmental impact caused by greenhouse gas emissions, particularly in land transportation, aligning with the global sustainable development goals and offering a promising path towards a more sustainable future. The proposed method implicates direct cargo transportation from its origin to the export ports without passing through intermediate centers. The mathematical model determines the most efficient means of transportation for each route, considering variables such as distance, volume, and type of cargo. Research results indicate that multiple hubs may not be necessary in scenarios with high freight concentration, which could streamline transportation and logistics operations. The modal preferences vary depending on regional dynamics and cargo characteristics, with rail and sea transport emerging as preferable options in specific circumstances, outperforming road transport. The proposed model shows reductions in logistics costs and CO2 emissions compared to road-focused scenarios. This study provides an adaptable framework for optimizing multimodal transportation systems in regions with similar geographic and logistical attributes. It offers a versatile solution to various contexts and needs. Lastly, the strategic integration of multiple modes of transportation is fundamental to improving efficiency and sustainability.
Sensing Pre- and Post-Ecdysis of Tropical Rock Lobsters, Panulirus ornatus, Using a Low-Cost Novel Spectral Camera
Authors: Sutherland Charles , Henderson Alan D. , Giosio Dean R. , Trotter Andrew J. , Smith Greg G.
Published: June 2024

Tropical rock lobsters (Panulirus ornatus) are a highly cannibalistic species with intermoult animals predominantly attacking animals during ecdysis (moulting). Rapid, positive characterisation of pre-ecdysis lobsters may open a pathway to disrupt cannibalism. Ecdysial suture line development is considered for pre-ecdysis recognition with suture line definition compared for intermoult and pre-ecdysis lobsters emerged and immerged, using white, near ultraviolet (365 nm), near infrared (850 nm), and specialty SFH 4737 broadband IR LEDs against a reference of intermoult lobsters with no suture line development. Difficulties in acquiring suture line images prompted research into pre-ecdysis characterisation from the lobster’s dorsal carapace, due to its accessibility through a culture vessel’s surface. In this study, a novel low-cost spectral camera was developed by coordinating an IMX219 image sensor, an AS7265x spectral sensor, and four SFH 4737 broadband infrared LEDs through a single-board computer. Images and spectral data from the lobster’s dorsal carapace were acquired from intermoult, pre-ecdysis, and post-ecdysis lobsters. For the first time, suture line definition was found to be enhanced under 850 nm, 365 nm, and SFH 4737 LEDs for immerged lobsters, while the 850 nm LED achieved the best suture line definition of emerged lobsters. Although the spectral camera was unable to characterise pre-ecdysis, its development was validated when a least squares regression for binary classification decision boundary successfully separated 86.7% of post-ecdysis lobsters. Achieving post-ecdysis characterisation is the first time the dorsal carapace surface has been used to characterise a moult stage for palinurid lobsters.
Electro-Mechanical Coupling Analysis of L-Shaped Three-Dimensional Braided Piezoelectric Composites Vibration Energy Harvester
Authors: Sun Mengfei , Song Ming , Wei Gaofeng , Hua Fengfeng
Published: June 2024

In this article, an L-shaped three-dimensional (3D) braided piezoelectric composite energy harvester (BPCEH) is established, which consists of an elastic layer composed of a 3D braided composite, flanked by upper and lower layers of piezoelectric material and two tuning mass blocks. Glass fiber and epoxy resin are used to produce a 3D braided composite. This L-shaped 3D BPCEH is mechanically designable and can be adapted to different work requirements by varying the braided angle of the 3D braided composite layer. The material parameters of 3D braided composites are predicted for different braided angles by means of a representative volume element (RVE). Electro-mechanical coupled vibration equations for the L-shaped 3D BPCEH are established. The impact of braided angles on voltage and power output is discussed in this article. Simulations using finite element method are conducted to analyze the voltage and power output responses at various braided angles. In addition, the effects of the mass of mass block B and the length of the beam on the output performance of the L-shaped 3D BPCEH are analyzed.
Influence of the Polymerization Parameters on the Porosity and Thermal Stability of Polymeric Monoliths
Authors: Maciejewska Małgorzata
Published: June 2024

Rigid porous polymeric monoliths are robust, highly efficient, versatile stationary phases. They offer simple preparation and convenient modification provided by a whole range of synthesis factors, e.g., starting monomers, cross-linkers, initiators, porogens, polymerization techniques, and temperature. The main aim of this study was to synthesize polymeric monoliths and determine the correlation between polymerization parameters and the porosity and thermal stability of the obtained materials. Polymeric monoliths were synthesized directly in HPLC columns using N-vinyl-2-pyrrolidone (NVP) and 4-vinylpiridine (4VP) as functional monomers, with trimethylolpropane trimethacrylate (TRIM) serving as the cross-linking monomer. During copolymerization a mixture of cyclohexanol/decane-1-ol was used as the pore-forming diluent. Polymerization was carried out at two different temperatures: 55 and 75 °C. As a result, monoliths with highly developed internal structure were synthesized. The value of their specific surface area was in the range of 92 m2/g to 598 m2/g, depending on the monomer composition and polymerization temperature. Thermal properties of the obtained materials were investigated by means of thermogravimetry (TG). Significant differences in thermal behavior were noticed between monoliths synthesized at 55 and 75 °C. Additionally, the poly(NVP-co-TRIM) monolith was successfully applied in GC analyses.
Laboratory Tests on the Possibility of Using Flax Fibers as a Plant-Origin Reinforcement Component in Composite Friction Materials for Vehicle Braking Systems
Authors: Borawski Andrzej , Szpica Dariusz , Mieczkowski Grzegorz
Published: June 2024

Braking systems are extremely important in any vehicle. They convert the kinetic energy of motion into thermal energy that is dissipated into the atmosphere. Different vehicle groups have different nominal and maximum speeds and masses, so the amount of thermal energy that needs to be absorbed by the friction pads and then dissipated can vary significantly. Conventional friction materials are composite materials capable of withstanding high temperatures (in the order of 500–600 °C) and high mechanical loads resulting from braking intensity and vehicle weight. In small vehicles traveling at low speeds, where both the amount of thermal energy and its density are limited, the use of slightly weaker friction materials with better ecological properties can be considered. This work proposes a prototype composite friction material using flax fibers as reinforcement instead of the commonly used aramid. A number of samples were prepared and subjected to laboratory tests. The samples were prepared using components of plant origin, specifically flax fibers. This component acted as reinforcement in the composite friction material, replacing aramid commonly used for this purpose. The main tribological characteristics were determined, such as the values of the coefficients of friction and the coefficients of abrasive wear rate. For this purpose, an authorial method using ball-cratering contact was used. The results were analyzed using statistical methods. It was found that the composite material using flax fibers does not differ significantly in its tribological properties from conventional solutions; so, it can be assumed that it can be used in the vehicle’s braking system.
The Effect of Cesium Incorporation on the Vibrational and Elastic Properties of Methylammonium Lead Chloride Perovskite Single Crystals
Authors: Junaid Syed Bilal , Naqvi Furqanul Hassan , Ko Jae-Hyeon
Published: June 2024

Hybrid organic-inorganic lead halide perovskites (LHPs) have emerged as a highly significant class of materials due to their tunable and adaptable properties, which make them suitable for a wide range of applications. One of the strategies for tuning and optimizing LHP-based devices is the substitution of cations and/or anions in LHPs. The impact of Cs substitution at the A site on the structural, vibrational, and elastic properties of MAxCs1−xPbCl3-mixed single crystals was investigated using X-ray diffraction (XRD) and Raman and Brillouin light scattering techniques. The XRD results confirmed the successful synthesis of impurity-free single crystals, which exhibited a phase coexistence of dominant cubic and minor orthorhombic symmetries. Raman spectroscopy was used to analyze the vibrational modes associated with the PbCl6 octahedra and the A-site cation movements, thereby revealing the influence of cesium incorporation on the lattice dynamics. Brillouin spectroscopy was employed to investigate the changes in elastic properties resulting from the Cs substitution. The incorporation of Cs cations induced lattice distortions within the inorganic framework, disrupting the hydrogen bonding between the MA cations and PbCl6 octahedra, which in turn affected the elastic constants and the sound velocities. The substitution of the MA cations with smaller Cs cations resulted in a stiffer lattice structure, with the two elastic constants increasing up to a Cs content of 30%. The current findings facilitate a fundamental understanding of mixed lead chloride perovskite materials, providing valuable insights into their structural and vibrational properties.
Development and Experimental Verification of Inorganic Electromagnetic Pulse Shielding Paint for Building Interiors Using Carbon-Based Materials
Authors: Jang Kyong-Pil
Published: June 2024

The term electromagnetic pulse (EMP) generally refers to high-power electromagnetic waves and can be classified into EMPs caused by nuclear weapons, non-nuclear EMPs, and EMPs caused by natural phenomena. EMPs can cause catastrophic damage to any electronic device consisting of electromagnetic components, including communications devices and transportation. In this study, the shielding effectiveness of paint was evaluated depending on the type and content of carbon material and binder. To analyze the compatibility and dispersibility improvement of the raw materials used in paint manufacturing, experiments were conducted in two stages, using 27 mixtures. The shielding effectiveness was evaluated for the optimal mixture developed through mixture experiments. The results of this study confirmed that the developed EMP shielding paint can improve the shielding effectiveness of concrete by 25–40 dB. Additionally, the adhesion strength and moisture resistance evaluation of the EMP shielding paint were evaluated. The average adhesive strength of the EMP shielding paint was 1.26 MPa. In moisture-resistance testing at a temperature of 50 ± 3 °C and a relative humidity of 95% or higher for more than 120 h, no cracks or peeling were observed on the painted surface.
Comparison of Magnetron-Sputtered and Cathodic Arc-Deposited Ti and Cr Thin Films on Stainless Steel for Bipolar Plates
Authors: Fredebeul-Beverungen Nils , Steinhorst Maximilian , Roch Teja
Published: June 2024

In this work, the potential of magnetron sputtering, as well as cathodic arc evaporation, is investigated with regard to its suitability as a bipolar plate coating of a PEM fuel cell. For this purpose, Cr and Ti thin films were deposited onto a 0.1 mm SS316L by varying the power and bias voltage. The surface structure and thickness of the coatings are examined via SEM and tactile profilometry. Moreover, the coating variants are compared with each other based on the electrical and electrochemical properties relevant to bipolar plates. The sputtered Cr thin films achieve the lowest contact resistance values and exhibit a columnar structure with a smooth surface. Regarding the electrochemical properties, titanium deposited via cathodic arc evaporation has a low current density in the passive region and high breakthrough potential. All in all, both deposition techniques have their individual advantages for the preparation of bipolar plates’ coatings. However, Ti thin films prepared via cathodic arc seem to be the most suitable option due to the combination of a high deposition rate, a low cost and good coating properties.
Enhancement Effect of Aggregates on the Low-Temperature Cracking Resistance of Asphalt Mixtures
Authors: Du Jianhuan , Fu Zhu
Published: June 2024

Aggregates’ configurations result in different stress fields, which change the fracture mode and mechanical properties of an asphalt mixture. To reveal the enhancing effect of aggregates with different particle sizes on the low-temperature cracking resistance of an asphalt mixture, an indirect tensile (IDT) test was carried out to analyze the aggregates’ influence on crack propagation and low-temperature cracking resistance from a macroscopic perspective. And combined with the test results, mesostructure models of an asphalt mixture with different aggregates’ spatial distributions were established through the extended finite element method (XFEM) to analyze changes in the crack propagation path and crack tip configuration force from a mesoscopic perspective. The main results showed that the crack tip configurational force was reduced due to the aggregate size increasing, demonstrating the inhibitory effect of aggregates on crack propagation. This contributes to enhancing asphalt mixtures’ low-temperature cracking resistance. Compared to single-grain aggregates, multi-grain aggregates exhibit a greater inhibitory effect on crack propagation. Nonetheless, an excessive disparity in particle sizes compromises particle continuity, leading to the formation of more branching cracks. Meanwhile, the aggregates’ inhibitory effect on crack propagation is influenced by the crack deflection angle. In particular, when the crack deflection angle, β, equals 45°, the crack tip’s configurational force is notably larger, leading the crack to enter an unstable state conducive to the expansion and formation of macrocracks. The research results reveal aggregates’ inhibitory effect on crack propagation from a macro- and microperspective and reveal the relationship between aggregate configurations and the low-temperature cracking resistance of asphalt mixtures.
On the Classification of Entire Solutions to the Critical Lane–Emden Equation
Authors: Sun Shenghui , Han Fei
Published: June 2024

The positive solutions to the critical Lane–Emden equation in Rn have been classified completely by the moving plane method. Afterwards, with additional conditions such as limited energy or volume, there is proof that relies entirely on integration by parts and inequalities techniques. In this paper, the authors provide a new approach to obtain the same classification results without further assumptions.
Effects of a β-Glucan-Rich Blend of Medicinal Mushrooms and Botanicals on Innate Immune Cell Activation and Function Are Enhanced by a Very Low Dose of Bovine Colostrum Peptides
Authors: Jensen Gitte S. , Cruickshank Dina , Hamilton Debby E.
Published: June 2024

Nutraceutical immune support offers potential for designing blends with complementary mechanisms of action for robust support of innate immune alertness. We documented enhanced immune activation when bovine colostrum peptides (BC-Pep) were added to an immune blend (IB) containing β-glucans from yeast, shiitake, maitake, and botanical non-β-glucan polysaccharides. Human peripheral blood mononuclear cells (PBMCs) were cultured with IB, BC-Pep, and IB + BC-Pep for 20 h, whereafter expression of the activation marker CD69 was evaluated on NK cells, NKT cells, and T cells. Cytokine levels were tested in culture supernatants. PBMCs were co-cultured with K562 target cells to evaluate T cell-mediated cytotoxicity. IB + BC-Pep triggered highly significant increases in IL-1β, IL-6, and TNF-α, above that of cultures treated with matching doses of either IB or BC-Pep. NK cell and T cell activation was increased by IB + BC-Pep, reaching levels of CD69 expression several fold higher than either BC-Pep or IB alone. IB + BC-Pep significantly increased T cell-mediated cytotoxic killing of K562 target cells. This synergistic effect suggests unique amplification of signal transduction of NK cells and T cells due to modulation of IB-induced signaling pathways by BC-Pep and is of interest for further pre-clinical and clinical testing of immune defense activity against virally infected and transformed cells.
Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling
Authors: Xia Ning , Gao Fengli , Zhang Jiwen , Wang Jiaqiang , Huang Yaliang
Published: June 2024

Enzyme-linked electrochemical immunosensors have attracted considerable attention for the sensitive and selective detection of various targets in clinical diagnosis, food quality control, and environmental analysis. In order to improve the performances of conventional immunoassays, significant efforts have been made to couple enzyme-linked or nanozyme-based catalysis and redox cycling for signal amplification. The current review summarizes the recent advances in the development of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling for signal amplification. The special features of redox cycling reactions and their synergistic functions in signal amplification are discussed. Additionally, the current challenges and future directions of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling are addressed.