bluuebunny/crossref_metadata_2025 huggingface dataset:
Infective endocarditis in the elderly: The current view of the problem
Authors: Taradin G G , Vatutin N T , Prendergast B D , Newton J D , Chaus E A , Smyrnova A S
Published: December 2016

The review gives the current views of the etiology and risk factors of infective endocarditis (IE) in the elderly. It reports the specific clinical picture of the disease at this age, including clinically apparent syndromes, comorbidity, and various clinical signs and peculiarities of IE. Particular emphasis is placed on the diagnosis of an endocardial infectious lesion, which is based on the use of the modified Duke criteria. The methods of IE diagnosis, particularly microbiological examination, imaging techniques, among which echocardiography in different modes plays a particular role, are listed. The treatment of the disease is based on the latest recommendations for antibiotic therapy with and without regard to a specific etiological factor. The issues of surgical intervention, as well as approaches to preventing IE in elderly people are discussed.
Possibilities of using cepeginterferon alpha-2b in double (cepeginterferon alfa-2b and ribavirin) and triple (simeprevir, cepeginterferon alpha-2b, and ribavirin) antiviral therapy regimens for chronic hepatitis C. A review of clinical trials and experience of everyday clinical practice
Authors: Znoyko O O , Klimova E A , Maevskaya M V , Shuldyakov А A , Linkova Yu N , Morozova M A
Published: December 2016

Since the incidence of chronic hepatitis C (CHC) increases steadily, the priority of national health care is to provide antiviral therapy (AVT) for the maximum number of patients infected with hepatitis C virus (HCV). The regimens including pegylated interferons (PEG-IFN) are still in demand in the Russian Federation. A number of clinical trials have been conducted to evaluate the efficacy and safety of cepeginterferon alpha-2b (cePEG-IFN alpha-2b), an original PEG-IFN-α developed in the Russian Federation. Their results have shown that cePEG-IFN alpha-2b in the two-component AVT regimen has at least no less clinical efficacy than PEG-IFN alpha-2b and PEG-INF alpha-2a in HCV monoinfected and HCV/HIV co-infected patients. The pooled analysis of data has indicated that the use of cePEG-IFN alpha-b in combination with ribavirin allows an average of 80% of the patients with HCV genotypes 2 and 3 and 62% of those with HCV genotype 1 to achieve a sustained virological response (SVR). In clinical practice when the two-component AVT regimen (cePEG-IFN alpha-b and ribavirin) was used in patients with early-stage CHC and mild fibrosis, SVR was recorded in 90.7% of the patients with HCV genotype 2/3 and in 75% of those with HCV genotype 1. The experience in using cePEG-IFN alpha-2b as a component of the three-component AVT regimen (simeprevir, cePEG IFN alfa-2b, and ribavirin) has been published. The observational program manly covered young patients with mild or moderate fibrosis. SVR was observed in 94% of the patients. Another paper describes the experience with the triple AVT therapy (simeprevir, cePEG-IFN alfa-2b, and ribavirin) in 22 patients, the majority of whom had advanced fibrosis. SVR was recorded in 71.4% of those who had completed treatment. Thus, an individual approach and assessment of predictive response factors to two- or three-component AVT regimens including cePEG-IFN alpha 2b can achieve successful treatment outcomes in most patients with CHC, which is, in some cases, more economically sound than interferon-free regimens used as first-line therapy.
The impact of tuberculosis and chemotherapy on female reproductive health
Authors: Kayukova S I
Published: December 2016

The paper outlines a concise review of Russian and foreign literature on the specific features of the course of respiratory tuberculosis in reproductive-aged women. It shows the impact of active tuberculosis and massive chemotherapy on the reproductive system, analyzes clinical symptoms, immediate and long-term consequences, and prognosis of future reproductive function. The timely diagnosis and optimal correction of reproductive disorders in women with respiratory tuberculosis can improve their quality of life, fertile capacities, and birth of a successive healthy offspring
Follow-up of patients with Ixodes tick-borne borrelioses caused by Borrelia miyamotoi or Borrelia burgdorferi sensu lato
Authors: Bagautdinova L I , Platonov A E , Sarksyan D S , Stukolova O V , Shipulin G A , Maleev V V , Dudarev M V
Published: December 2016

Ixodes tick-borne borrelioses (ITBB) are caused by two different spirochetes: Borrelia from the group of Borrelia burgdorferi sensu lato, the agents of the classic Lyme borreliosis (LB), and Borrelia miyamotoi that belongs to the group of Borrelia causing tick-borne relapsing fevers. ITBB caused by B. miyamotoi (BM-ITBB) is a previously unknown infectious disease discovered in Russia. It is known that the LB sequelae may reduce the long-term life guality of convalescents. Aim. To study the follow-up of those who have recovered from new BM-ITBB infection in comparison with persons who have had LB. Subjects and methods. The investigation enrolled 41 patients with BM-ITBB and 41 patients with LB who were treated at the Republican Infectious Diseases Hospital of Udmurtia. Within a year after the disease, they were followed up through clinical and instrumental examination of cardiac performance, expanded biochemical analysis of blood and urine, which could; estimate kidney and liver functions, and psychological questioning. Results. Asthenic syndrome and complaints about and objective signs of cardiac dysfunctions persisted supraventricular extrasystoles, left ventricular diastolic dysfunction, and elevated and/or unstable systolic blood pressure were detected in 20-30% of the convalescents for a long time. Kidney dysfunctions were manifested in albuminuria and the decrease of glomerular filtration rate. A year following the disease, 10-20% patients had persistently elevated concentrations of alanine aminotransferase, aspartate aminotransferase, and C-reactive protein and had higher levels of total cholesterol and low-density lipoproteins. The pathological consequences of ITBB were polymorphic and varied in different patients; in general, only 68% of them showed health improvement. Conclusion. We assume that a significant role in the pathogenesis of BM-ITBB and LB is played by vascular endothelial damage possibly associated with the inflammatory and autoimmune aspects of an immune response in Borrelia infection. The consequences of this damage may persist and even intensify during a year, which provokes chronic dysfunction of the heart, kidney, or liver in a number of convalescents.
Tick-borne neuroinfections: Clinical characteristics, immunopathogenesis, and new pharmacotherapeutic strategies
Authors: Konkova-reidman A B
Published: December 2016

Aim. To study the semiotics of neurological lesions in patients with tick-borne encephalitis, Ixodes tick-borne borreliosis (ITBB) and mixed infection (MI), their immunopathogenesis, and the possibilities of current pathogenetic pharmacological correction. Subjects and methods. A total of 220 patients with tick-borne encephalitis, ITBB, and MI concurrent with the syndromes of central nervous system lesions were examined. The immunological studies encompassed the examination of mononuclear cells in the cerebrospinal fluid (CSF), the population and subpopulation composition of lymphocytes, and nitroxidergic processes in the serum and CSF from the total level of final stable nitric oxide metabolites. For pharmacotherapeutic correction, the metabolic drug cytoflavin was used as newly indicated. Results. Cytofluorometric analysis of the CSF cellular composition showed the mononuclear cell predominance of CD3+ (58.6%), CD4+ (57.2%), CD8+ (16.8%) lymphocytes and monocytes (34.4%), which expressed the phenotypic marker CD14+. This reflects the nature of a local immune response: an increase in the immunoregulatory index CD4+/CD8+ from 3.4 to 5.6, respectively, while the normal proportion of these cells in the blood ranges from 1.5 to 2.2. CSF lymphocytes were found to be ready for Fas-mediated apoptosis dependent on the receptor (CD95+ was 64.3%).There was a correlation using the pair correlation coefficient between the total concentration of the metabolites of the nitroxide molecule and the percentage of CD14+ (r=0.5; p
Treatment for acute respiratory viral infection and influenza in daily clinical practice: Results of the multicenter international observational FLU-EE study
Authors: Fazylov V Kh , Sitnikov I G , Silina E V , Shevchenko S B , Mozhina L N , Zamyatina L L , Yeganyan G A , Groppa L G , Korsantia B M
Published: December 2016

Purpose: To study the clinical aspects of influenza and acute respiratory viral infection (ARVI) in routine clinical practice, with efficacy and safety of the antiviral therapy evaluation. Subjects and methods: In the large multicenter prospective observational study were enrolled 18,946 patients aged 18 to 93 years with previously determined diagnosis of influenza or ARVI from 262 outpatient sites in Russia, Armenia, Moldova and Georgia. According to study design, 3 visits were evaluated. On each visit the detailed medical examination, determination of individual symptoms’ severity and course of disease were made. The dynamic evaluation of prescribed in routine clinical practice therapy of influenza and ARVI and cases of disease exacerbations with antibiotics concomitant therapy were assessed. Results: For the first time in outpatient practice on a large population of adult patients the objective data were obtained and analyzed. This data relating to the timing of access to medical care of patients with influenza and ARVI depending on the age and the disease severity, dynamics of clinical picture of the disease, their outcomes, timing recovery, as well as ongoing drug therapy of ARVI and influenza, allowed to identify patterns of development and course of these diseases. The effectiveness and safety of antiviral drug Kagocel for treatment of ARVI and influenza was shown. This is reflected in the improvement of the clinical picture of the disease; reducing the number of patients with exacerbations, requiring the prescription of systemic antibiotics up to 1.5 times; the acceleration of regression of symptoms and recovery periods. Conclusion: This study allows increase the level of objective assessment of the beginning and course of influenza and other ARVIs in outpatient practice, to predict their course and outcome, and to improve the treatment
Evaluation of the pharmacoeconomic efficacy of prestance in the treatment of hypertensive patients on the basis of the results of the POTENTIAL program
Authors: Dyakov I N , Glezer M G
Published: December 2016

Aim. To pharmacoeconomically estimate the use of a fixed-dose combination of perindopril and amlodipine in the treatment of hypertensive patients. Materials and methods. A pharmacoeconomic study was conducted on the basis of the Russian postmarketing observational open program POTENTIAL, which included the estimation of direct and indirect costs associated with the addition of a fixed-dose combination of perindopril and amlodipine to conventional therapy for hypertension in patients who had not achieved adequate blood pressure (BP) control. Cost-difference, cost-effectiveness, and budget-impact analyses were carried out. Results. The addition of prestance to conventional therapy for hypertension can reduce total costs by 5.-5.8 times, direct costs required to achieve 1% of patients with adequate BP control by 20.5-42.1 times, and direct costs to improve a patient’s status by one visual analogue scale score by 1.03-2.11 times. Within a 5-year horizon, the administration of prestance can decrease the cost of therapy for high BP and related strokes by 1.39-1.46 times. Conclusion. Due its high efficacy, prestance (amlodipine + perindopril) is a pharmacoeconomically preferred alternative only to the conventional therapy for hypertension even if the least costly generics are used, in both the short and medium term.
A case of progressive multifocal leukoencephalopathy in a HIV-infected female patient
Authors: Samotolkina E A , Pokrovskaya A V , Samotolkina E S , Voznesensky S L , Petrova E V
Published: December 2016

Progressive multifocal leukoencephalopathy (PML) caused by JC virus is a severe central nervous lesion developing in the presence of obvious immunodeficiency. In most cases, the disease results in a fatal outcome within a few months. Antiretroviral therapy is currently considered to be the only method for the prevention and treatment of PML in HIV-infected patients. The paper describes a positive experience in treating the HIV-infected female patient with the established diagnosis of PML.
Dominant values of family purposefulness depending on some socio-demographic factors
Authors: Nozikova N.V.
Published: December 2016

The article presents the data of the empirical study of the dominant values of family purposefulness, depending on several socio-demographic factors (sex, and the presence / absence of his family according to the age). 50 girls and 50 boys of 15—18 age participated in the research; 50 women of 21—44 age and 45 men of 20—42 age, who are married and have children. Computer program Osgood of semantic differential technique modified by
I.L. Solomina was applied. According to the purpose of the study there are chosen: 1) category of concepts related to the family life (people and groups, events, activities and ideal representation); 2) the concept of markers defining the basic values, stages of life, people, groups of people and attitude to them, gender concepts, activities, emotional feelings and events. It is brought out the dependence of the dominant values from sex factor. So, the girls have the dominance of the value concept “my future family”, the young men — “my future wife”. “The birth of a child” is the general dominant value for male and female, who are married and have children.
Manifestations of the “3 year old child´s crisis” in relation to characteristics of the parent-child interaction
Authors: Ulanova Y. , Vasilenko V.E.
Published: December 2016

This article is devoted to analysis of the predictors of the “3 years old childґs crisis” in the field of parent-child interaction (parenting styles, peculiarities of emotional interaction mothers with children, characteristics of family adaptation and cohe- sion). The study involved 117 children (65 boys and 52 girls) and 117 their mothers from Vsevolozhsk district of the Leningrad region. The age of children — from 2 years 1 month to 3 years 11 month, Mage = 3 years. We used psychodiagnostic methods and the method of observation. The study revealed that the period from 2 years 1 month to 2 years 9 months is characterized by signs of subcritical phase, critical phase was observed after 2 years 10 months. “3 year old childґs crisis” is more pronounced at lower emotional acceptance of the child, maternal educational uncertainty, underdevelop- ment of parental feelings, indulgence overprotection, immaturity of maternal emotion- al behavior in actual interaction of mothers with children. At the same time the crisis manifestations can be expressed in the case of well-being in family functioning and emotional interaction (family cohesion, the sensitivity of the mother to child), which confirms the normativity of the “3 years old childґs crisis”.
Efeito do Samba e da Valsa na Mobilidade Funcional de Pacientes com Doença de Parkinson
Authors: Fragnani Samuel Geraldi , Bezerra Poliana Penasso
Published: December 2016

Estudos evidenciam a música como uma intervenção terapêutica importante para indivíduos com doença de Parkinson. O fornecimento dos estímulos espaciais e temporais desta intervenção pode sinalizar as fases do ciclo da marcha proporcionando ao portador da doença um andar mais fluente. Além deste benefício, a terapia por meio da música possibilita ao indivíduo aumento de sua autoestima, maior conforto, relaxamento, bem-estar e proporciona maiores interações quando o tratamento é realizado em grupo. Neste estudo objetivou-se analisar o efeito que os gêneros musicais, valsa e samba, promovem na mobilidade funcional em indivíduos com doença de Parkinson. Os voluntários desta pesquisa realizaram o Timed Up and Go Test (TUG) nas situações: sem música, música clássica (valsa) e música popular brasileira (samba). Os dados obtidos foram ponderados por análise estatística descritiva e inferencial com teste Fridman e post-hoc de Wilcoxon pareado (nível de significância de 5%). Os achados evidenciam que o samba promoveu efeito adverso na marcha reduzindo a velocidade (p=0,04), número de passos (p=0,04) e cadência (p=0,04), aumentando o tempo (p=0,04) e comprimento de passos (p=0,05) quando comparado á condição sem música. Entendemos que os fatores intrínsecos da música como ritmo, harmonia, melodia e amplitude podem estar associados com o efeito adverso observado na mobilidade funcional de pacientes com doença de Parkinson.
Vivências Familiares de Adolescentes Usuários de Drogas
Authors: Pimentel Rafael Rodrigo da Silva , Soares Thaís Fukunishi , Ribas Adriana Danmvof , Scardoelli Márcia Glaciela da Cruz
Published: December 2016

O objetivo deste estudo foi compreender a vivência da família com adolescente usuário de álcool e substâncias psicoativas. Pesquisa descritiva de abordagem qualitativa realizada no período de julho a setembro de 2015. Participaram deste estudo, cinco familiares de usuários de crack e outras substâncias psicoativas. A coleta de dados foi realizada por meio de entrevistas com questionário semiestruturados contendo questões abertas e fechadas. Para análise dos dados utilizou-se a técnica de análise de conteúdo modalidade temática proposta por Minayo (2007). Os resultados demonstraram os prejuízos afetivos que o uso de drogas pelo adolescente traz para seus familiares, expressados por sentimentos de raiva, angustia, medo, preocupação. Além da sobrecarga de trabalho e cuidados expressa pelo adolescente. Diante disso, o estudo mostrou a necessidade de uma atenção voltada para o familiar do usuário de drogas.
Presentación. Territorio, Ciudad y Arquitectura
Authors:   Universidad de Cuenca, Jaramillo Medina Carlos
Published: December 2016

Lo que se escribe en un espacio académico, en este caso la Facultad de Arquitectura, se constituye en lo que se piensa y lo que se quiere hacer; en las reflexiones y en sus aplicaciones posibles en torno a temas relacionados con el territorio, la ciudad y la arquitectura. La Revista ESTOA N° 2 presenta varios artículos referidos a estas dos grandes tareas.
Health, environment and territory: a vision integrated in a globalized world
Authors:   Universidad Politécnica de Madrid, Gómez Orea Domingo , Gómez Villarino María Teresa ,   Melissa, Consultoría e Ingeniería Ambiental, S.L., Gómez Villarino Miguel ,   Melissa, Consultoría e Ingeniería Ambiental, S.L.
Published: December 2016

El modelo actual de desarrollo es económicamente globalista y deslocalizado territorialmente, siguiendo un patrón centro-periferia que acumula actividades y población en unas zonas mientras desertiza otras. Este modelo es económica, social y ambientalmente insostenible y energéticamente ineficiente porque exige la producción concentrada de la energía, porque requiere el desplazamiento de cantidades ingentes de mercancías y porque dificulta el aprovechamiento de las energías renovables que suelen disponerse de forma difusa en el territorio.El artículo plantea las repercusiones de este modelo para la salud y los beneficios que produciría el modelo alternativo propuesto.Frente a lo anterior, el artículo propone un modelo polinuclear y en red, con asentamientos compactos de diverso nivel y tamaño, polifuncionales, cubriendo todo el espacio, conectados por canales de relación que les proporcionen parecidas oportunidades de acceso a centros, ciencia, cultura, ocio, etcétera.
Urban chronotope. Cuenca of Los Andes
Authors:   Universidad de Cuenca, Jaramillo Medina Carlos
Published: December 2016

Las nuevas lecturas de los centros históricos buscan enfoques y métodos alternativos para comprender sus sentidos naturales, culturales e históricos. Estos esfuerzos epistemológicos quieren superar las visiones parcializadas positivistas del paradigma moderno.El presente texto trata de comprender el Centro Histórico de Cuenca desde otras miradas. Para alcanzar este propósito se consultan varias fuentes postmodernas y contemporáneas, incluyendo el sugestivo trabajo de Álvaro Niño denominado "La Gesta del Signo. Hacia un semanálisis urbano."Este ensayo se divide en cinco partes: primero se presentan referencias teóricas y metodológicas para abordar el objeto de estudio; luego se exponen arquetipos, vectores y fenotipos urbanos; y por último se plantea esta hipótesis: el Centro Histórico de Cuenca puede ser considerado un cronotopo urbano, es decir, una alternativa natural, urbana y arquitectónica de interpretación múltiple, intertextual y de asociaciones de naturaleza rizomática.
Design and validation of bioclimatic housing for the city of Cuenca
Authors:   Universidad de Cuenca, Cordero Ximena , Guillén Vanessa ,   Universidad de Cuenca
Published: December 2016

Este estudio de diseño y validación de vivienda bioclimática para el la ciudad de Cuenca se ha dividido en dos secciones: En la primera parte se dan a conocer los resultados de un procesamiento de datos climatológicos de la ciudad, con lo cual se determina la influencia de cada uno de éstos hacia su entorno. Posteriormente se mostrará su aplicación en el diagrama bioclimático de Givoni y finalmente se hará un breve análisis de otros factores ambientales que influyen en el confort de los espacios habitables.En la segunda parte se plantea el diseño de una vivienda bioclimática a nivel de anteproyecto, la misma que ha sido evaluada y validada mediante el uso de un software y cálculos matemáticos, basados en normas nacionales e internacionales.
Graphic-digital expression: a perspective
Authors:   Universidad de Cuenca, Orellana Boris
Published: December 2016

El uso del ordenador como herramienta efectiva de diseño en el campo de la arquitectura ha sido tema de discusión desde hace décadas. El análisis conjunto y ordenado para establecer una correcta pedagogía, aplicación, investigación y desarrollo tecnológico ha dado lugar a diversas organizaciones, como por ejemplo la Asociación para el Diseño Asistido por Ordenador en la Arquitectura, fundada en 1981 y que hasta la fecha se mantiene como una de las instituciones de mayor prestigio a nivel mundial (acadia s.f.).
Influence of Non‐Impacted Third Molars on Pathologies of Adjacent Second Molars: A Retrospective Study
Authors: Li Zhi‐Bang , Qu Hong‐Lei , Zhou Li‐Na , Tian Bei‐Min , Chen Fa‐Ming
Published: December 2016

Background: Although removal of impacted third molars (I‐M3s) is common in dental clinics, the decision to retain or remove asymptomatic non‐impacted third molars (N‐M3s) presents a significant challenge. This study investigates influence of N‐M3s on pathologies of adjacent second molars (A‐M2s).

Methods: Clinical status of M3s was evaluated, and presence of distal caries, external root resorption (ERR), and alveolar bone loss (ABL) of A‐M2s was assessed by orthopantomograms (OPGs). Prevalence of A‐M2 pathologies was evaluated and association between N‐M3s and pathologies of A‐M2s was analyzed by multivariate logistic regression. Significance level was set at 0.05.

Results: OPGs from 1,958 patients were included in the present study. Among these patients, 45.1% presented with at least one N‐M3, and 44.2% of retained M3s were non‐impacted. Where N‐M3s were present, prevalence of distal caries, ERR, and ABL of A‐M2s was 10.0%, 0.8%, and 40.4%, respectively. Although N‐M3s did not increase the odds of caries or ERR of A‐M2s, presence of N‐M3s was associated with 1.77 times higher likelihood of ABL from A‐M2s when data were adjusted for age and sex.

Conclusions: Presence of N‐M3s, even if they are asymptomatic, represents an important risk factor for periodontal health of A‐M2s. This finding should be considered during clinical decision making regarding retention or extraction of N‐M3s, especially when these teeth are non‐functional or when their removal will not affect overall occlusal function.
Enabling Cordial, Edge cordial and total cordial labeling of dragon curve fractal graph
Authors: Sathakathulla ِA. A.
Published: December 2016

A fractal is a mathematical set that typically displays self similar patterns. The dragon curves (Also Known as Highway dragon) was the first in this family and further, it lead to other studies too. For our study, this fractal has been considered as a graph and the same has been tested with enabling the labeling of cordial, edge cordial and total cordial labeling, and which may lead to continue the applied studies further.
A characterization of Sporadic Janko groups \(J_{2}\) and \(J_{3}\)
Authors: Yang Yong , Ye Zhongwen
Published: December 2016

Let \(G\) be a group and \(\omega(G)\) be the set of element orders of \(G\). Let \(k\in \omega(G)\) and \(s_{k}\) be the number of elements of order \(k\) in \(G\). Let nse\((G)=\{s_{k}\big|k\in \omega(G)\}\). In Asboei's work, the author proved that \(J_{1}\) is unique determined by nse\((G)\). In this paper, we prove that if \(G\) is a group such that nse\((G)=\)nse(\(H\)), where \(H=J_{2}\) or \(J_{3}\), then \(G\cong H\).
Analysis of Service Quality and Organizational Performance of Private Healthcare Facilities in Nairobi County, Kenya
Authors: Dinda Beatrice , Ojera Patrick B. , Mathews Bulitia Godrick
Published: December 2016

Private healthcare has a significant market share, approximately 50% in Sub –Saharan Africa. In Kenya, it contributes 22% of all health services. Despite the sector’s contribution, its annual growth rate continues declining from 5.2%, 3.5% and 2.3% in 2008, 2009 and 2010 respectively. Previous studies on service quality dimensions have focused on the relationship between tangibility, responsiveness, empathy, reliability, assurance, and customer satisfaction no studies have looked at elements of service quality such as competence and equity in relation to organizational performance. The main objective of this study was to analyze the relationship between service quality and organizational performance of private healthcare facilities in Nairobi. Theory of quality trilogy guided the study in a correlational survey research design. The population was 52 chief operation managers of 52 private health facilities accredited by NHIF in Nairobi. Pilot results (N=10) revealed 51-item instrument reliability ranged between α=0.700 and α=0.867 Results revealed Tangibles (β = 0.258, p = 0.005); responsiveness (β = 0.244, p = 0.007); Competence (β = 0.222, p = 0.032) and Equity (β = 0.248, p = 0.011) had positive significant effect on organizational performance of private health facilities in Nairobi. The study concluded that service quality practices (tangibles, responsiveness, competence and equity) were significant predictors of organizational performance. Recommendations were that facilities should continue enhancing service quality dimensions as these efforts improve organizational performance. The study provided a service quality management framework that will aid healthcare policy makers in strengthening the relationship between quality of care and organizational performance.
The Effects of Load on Transmural Differences in Contraction of Isolated Mouse Ventricular Cardiomyocytes
Authors: Khokhlova Anastasia , Iribe Gentaro , Katsnelson Leonid , Naruse Keiji , Solovyova Olga
Published: December 2016

Mechanical properties of cardiomyocytes from different transmural regions are heterogeneous in the left ventricular wall. The cardiomyocyte mechanical environment affects this heterogeneity because of mechano-electric feedback mechanisms. In the present study, we investigated the effects of load upon transmural differences in contraction of subendocardial (ENDO) and subepicardial (EPI) single cells isolated from the murine left ventricle. Various loads were applied to the cells using carbon fiber techniques for single myocytes. To simulate experimentally obtained results and to predict mechanisms underlying the cellular response to change in load, our mathematical models of the ENDO and EPI cells were used. Extent of the transmural gradient in the time course of contractions was independent of the loading conditions where unloaded and heavy loaded (isometric) contractions were examined, but the regional gradient of the relaxation time characteristics tended to decrease when the load decreased. Under auxotonic contractions, time to peak contraction (Tmax) was significantly longer in ENDO cells than in EPI cells at low preload. An increase in preload (axial stretch) prolonged Tmax in both cell types; however, the prolongation was greater in EPI cells, resulting in a decrease in transmural gradient in Tmax at high preload. The [Ca2+]i transient decay time constant was consistent with the greater preload dependency in Tmax of EPI cells. Our modified mathematical models reproduced experimental results, suggesting that differences in cooperativity of cross bridges and calcium troponin C complex interactions between the ENDO and EPI cardiomyocytes may contribute to the different cellular responses to stretch, which may provide a decrease in transmural dispersion of cellular shortening in the intact heart.
Models for Calculating Monthly Average Solar Radiation from Air Temperature in Swaziland
Authors: Dlamini Mgidi D. , Varkey Alakaparampil J. , Mkhonta Simiso K.
Published: December 2016

Solar radiation is the main energy source for mankind and an accurate data of solar radiation levels for a particular location is vital for the optimum operation of solar energy transducers such as photovoltaic cells and solar thermal collectors. In this work, we show that there is a linear relationship between recorded monthly average temperatures and solar radiation in Swaziland. The good correlation can be utilized to develop two mathematical models for the estimation of solar radiation: one from the measured monthly average temperatures and the other based on the square-root of the difference between measured maximum and minimum monthly average temperatures. Both models fit the data well and can be applied to estimate solar radiation in other parts of the region.
Ruptured Pseudoaneurysm of the Dorsalis Pedis Artery Following Ankle Arthroscopy
Authors: Wiske Clay P. , Itoga Nathan K. , Ullery Brant W. , Hunt Kenneth J. , Chandra Venita
Published: December 2016

Case:

We describe the case of a pseudoaneurysm of the dorsalis pedis artery that developed following a repeat ankle arthroscopy for persistent osseous impingement. The patient underwent attempted fluid aspiration for a presumed effusion, and ultimately experienced rupture of the pseudoaneurysm with substantial blood loss, which required emergency vascular repair.

Conclusion:

Anterior tibial artery and dorsalis pedis artery pseudoaneurysms are relatively rare, but they are well-documented complications of ankle arthroscopy; however, their clinical importance is poorly understood. To our knowledge, this is the first reported case of a ruptured pseudoaneurysm of the dorsalis pedis artery following ankle surgery, and it highlights the need for timely diagnosis.
PENGARUH DISPLAY PRODUCT TERHADAP KEPUTUSAN PEMBELIAN KONSUMEN PT. ACE HARDWARE SIDOARJO
Authors: Kusuma Wardhana Hefry Wika , Rochmaniah Ainur
Published: December 2016

A company that engages in the retail home furnishings that is rapidly evolving to have 98 branches / outlets spread across cities in Indonesia is PT. Ace Hardware Indonesia.Tbk. PT. Ace Hardware Sidoarjo is the 39th branch which was established in 2008. PT. Ace Hardware Sidoarjo is always trying to create a good image for their company along with the professional services market segment for the middle class and above with reasonable and competitive price, so that it will improve profitability significantly while understanding the part of the marketing concept. This study is aimed to analyze the effect of display products towards purchase decisions of the consumers of PT. Ace Hardware Sidoarjo. Respondents involved in this study were 100 respondents, with a purposive sampling method. Questionnaire data collection and analysis methods of quantitative analysis performed by simple linear regression using SPSS software for windows 16:00. From the results of the regression test, it was shown that variable has weak influence on the purchase decision variables. So, we can get the summary that the display product does not affect consumer’s purchase decision.
KONSTRUKSI BUDAYA KEHIDUPAN BERAGAMA HIZBUT TAHRIR DAN PENGIKUT AHMADIYAH BERBASIS KEARIFAN LOKAL DI KABUPATEN KONAWE SELATAN
Authors: Anggraini Dewi , Aswan Zanynu Muhammad
Published: December 2016

This study aims to investigate the implementation of religious life between Hizbut Tahrir and Ahmadiyah followers in South Konawe. The Islamic doctrines they understand influence the behavior of Hizbut Tahrir in religious life againstAhmadiyah followers in South Konawe. This study uses a qualitative along with phenomenological approach and there are two locations as the concentrations of the two beliefs: Wolasi in Ranowila village and Konda in Lamomea village. Islamic doctrines that affect the behavior of Hizbut-Tahrir religious life against Ahmadiyah followers in South Konawe are: a). Organizational Vision, b). Thought ReferenceSources, c). Products Interpretation, d) method. The creation of peace between Hizbut Tahrir and Ahmadiyah followers in South Konawe can not be separated from the following aspects: a). Graphic of Socio Religious as Local Tolerance Portraits, b). Houses of Worship as Symbols of Harmony and Tolerance Awareness, c). Elite Communication Network of Hizbut Tahrir and Ahmadiyah, d). Propagation Methods and Strategic Goals.
MEDIA MASSA DALAM BINGKAI KEKUASAAN (Analisis Wacana Berita Munas Golkar di Metrotv dan tvOne)
Authors: Anwari Anwari
Published: December 2016

There are two issues that are examined in this study (1) Do MetroTv and tvOne use a balanced or unbias perspective in telling reports on the 8th Golkar Assembly to the chairman of the Golkar candidates (2) Is there any discourse of domination in the news about the 8th Golkar Assembly. To tell these issues in depth, this study uses discourse analysis of Teun A Van Dijk models which are useful to know and understand whether MetroTV and TVOne use impartial perspective in telling the 8th Golkar Assembly for the candidates and that there is Golkar chairman domination in news discourse of the 8th Golkar Assembly. This study found that tvOne news was dominated by a candidate of Golkar chairman, Bakrie, while the other candidates are not given an equal share in announcing the nomination of Golkar chairman. In the mean time, MetroTV announcing the nomination of Golkar chairman candidates to the election of Golkar chairman for 2009-2014 period, and MetroTV also explained clearly to the community only, the other candidates are not given an equal share in announcing the chairman of Golkar. Nomination black list was there in the news of MetroTV which was done to marginalize other groups.
PENGARUH KOMUNIKASI TERAPEUTIK BIDAN TERHADAP KEPUASAN PASIEN BERSALIN DI RUMAH SAKIT BHAYANGKARA PUSDIK BRIMOB WATUKOSEK GEMPOL PASURUAN
Authors: Hakim M. Lukman , Sinduwiatmo Kukuh
Published: December 2016

The objective of this study is to explain the effect of therapeutic communication done by midwives toward maternity patient satisfaction in Bhayangkara Pusdik Brimob hospital in Watukosek, Gempol Pasuruan. This study uses a correlational approach. Of the 1034 population of maternity patients in 2012, the researcher took Yamane formula so that the sample in this study were 91 respondents. The analysis uses simple linear regression formula. The conclusion of this study is that the results of 4,798 t and a significance value of 0.000. Values greater than 4,798 t 1,987 t table (df = 91-2 = 89; α = 0.05) and 0,000 T test significance value less than 0.05, then H0 is rejected and H1 is accepted, ie there is an effect of therapeutic communication by midwives toward satisfaction of maternity patient. While the results of the test R2 (R Square) obtained at 0.794 that patient satisfaction influenced  by therapeutic communication is 79.4%, while 20.6% is influenced by other variables.
OPINI MAHASISWA TERHADAP WEBSITE UNIVERSITAS MUHAMMADIYAH SIDOARJO SEBAGAI MEDIA INFORMASI
Authors: Ifadah Zaqqiyatul , Rochmaniah Ainur
Published: December 2016

The aim of this research is to describe the students’ opinion of the website quality as an information media at University of Muhammadiyah Sidoarjo. The population of this research consists of 4.260 students of University of Muhammdiyah Sidoarjo. Random proposional technique is used as a technique sampling of this research  which takes 97 repondences as the samples. The technique of data analysis used in this research is descriptive statistic. To interpret the data the perception value is also used as the guideline. The results of this research indicate that the use quality and information quality of website as an information media at University of Muhammadiyah Sidoarjo are less good. The interaction quality of website as an information media at University of  Muhammadiyah Sidoarjo is not good and overall the respondence impression of website at University of Muhamamdiyah Sidoarjo is also not so good.
KEKERASAN TERHADAP PEREMPUAN DALAM FILM INDONESIA
Authors: Lestari Rizki Widya
Published: December 2016

This study aimed to analyze the depiction of violence experienced by women in the film "7 heart, 7 love, 7 women". These research method used textual analyses to interpret the signs that are produced in a media text are elements of violence experienced by women. The results showed that violence to the women include (a) physical violence, among others: strangling, pulling, injuring a pregnant woman, and rape, (b) symbolic violence, among others: (1) psychological violence: deceive, insult, infidelity; (2) financial violence: lack of accountability husband; (3) functional violence: restrictions on women's social role as executor of reproductive function.
OPINI MASYARAKAT TERHADAP KEGIATAN CORPORATE SOCIAL RESPONSIBILITY PT PABRIK GULA CANDI BARU
Authors: Wardhana Panca , Rochmaniah Ainur
Published: December 2016

The purpose of this study was to determine public opinion towards corporate social responsibility Candi Baru sugar factory. This research used descriptive quantitative method, from a population of 367 householders, while a sample of 79 respondents. The sampling technique used proportional sampling techniques and random sampling. Collecting data used literature study, questionnaires and interviews. Analyzing data used descriptive statistics. The result study stated that, Candi Baru sugar factory has conducted two types of corporate social responsibility, namely corporate social marketing and corporate philanthropy. Public opinion towards corporate social responsibility Candi Baru sugar factory has been well overall, but there were still negative opinion of the people. It caused by multiple factors, the distribution of the assistance provided was uneven, the shape and the amount of assistance provided is considered incompatible with pollution and losses caused by the activity of production companies, as well as their distrust of the objectivity of the company in selecting the target activity.
PENGARUH KOMUNIKASI PEMASARAN WISATA KUSUMA TIRTA MINAPOLITAN TERHADAP PENINGKATAN KUNJUNGAN WISATA BAHARI DI KABUPATEN SIDOARJO
Authors: Ningrum Dyah Ary Setya
Published: December 2016

The purpose of this research was to determine how marketing communications affect to the increase visits in the Marine Tourism Minapolitan Kusuma Tirta Sidoarjo. The method used quantitative explanative. This study population was an overall visitor Tirta Kusuma Minapolitan consisted of 100 people. The sampling technique in this research used Taro Yamane. This study used regression analysis with simple regression methods. Primary data collection technique used Likert Scale. The results of this study can be concluded that marketing communications activities have a significant impact on tourist visits to the Tirta Kusuma Minapolitan of value R 0.572 with a percentage of 32.7%.Keywords: communications, marketing, visit
The use of ethyl chloride spray in the treatment of postoperative pain
Authors: Hussain Aziza
Published: December 2016

Ethyl Chloride spray is used to reduce pain caused by injections or minor surgical procedures and for the temporary relief of minor sports injuries. Studies have shown that it is effective in reducing pain during brief procedures such as venepuncture and immunisation and also in management of pain from minor trauma in the emergency department. Its use as treatment for acute postoperative pain has not been described before and we demonstrate its successful use in the management of postoperative pain following laparoscopic sterilisation.
An anatomy of calendar effects in Thailand
Authors: Panyagometh Kamphol
Published: December 2016

This paper aimed to study the interaction and profitability of the five most well-established calendar effects: Halloween effect, January effect, turn-of-the-month effect, weekend effect, and Thai holiday effect. The author found that turn-of-the-month effect (TOM) and weekend effect were the strongest and most profitable effects in Thai stock markets. The equity premium over the sample during 2000–2015 was 4.40 per cent if there was TOM effect or weekend effect, and -2.13 per cent in other cases. This study narrowed down the number of calendar effects from five to two, leading to more effective and less complex summary of different seasonal effects.
Keywords: calendar effects, Halloween effect, holiday effect, January effect, turn-of-the-month effect, weekend effect. JEL Classification: C12, C22
How changing of different factors impacts the quantity of NGOs incomes in Ukraine
Authors: Tkachuk Iryna
Published: December 2016

The aim of the study is to identify the most important factors that influence the funding of Ukrainian NGOs and to determine how managing the changes in these factors can increase the income of NGOs. The topicality of the research is stipulated by the unsatisfactory state of Ukrainian NGOs and the lack of similar studies in Ukraine. The research was conducted based on the data on the income of Ukrainian NGOs from 2006 to 2013, as well as statistics on macroeconomic indices of Ukraine over the same period. The article provides the research of the impact of indices quantitatively characterizing their activities and indices of GDP according to distribution method on the volume of funding of Ukrainian public organizations. The authors have revealed that such indices as the number of registered members, the number of companies, institutions and organizations founded and created by the associations of citizens, compensation for hired employees; gross profit and mixed income have the greatest impact on funding. The authors have substantiated that the successful management of these parameters can significantly affect the funding of Ukrainian NGOs: the increase of the “Compensation of employees” parameter and the increase in “Profit and mixed income”, which is one of the priorities of the state, can lead to an almost proportional increase in the income of Ukrainian NGOs. The same result can be achieved by controlling "Number of registered members” parameter. The “Number of companies, institutions and organizations founded and created by the associations of citizens” parameter has the opposite effect on the income of Ukrainian NGOs.
Keywords: NGOs, NGOs incomes, scenario approach, factor analysis. JEL classification: C61, H41
The viability of asset price channel implementation to the monetary transmission mechanism of Ukraine
Authors: Kozmenko Serhiy , Plastun Oleksiy
Published: December 2016

Monetary transmission mechanism is a key element of the central bank’s activity, where the asset price channel plays an important role among others. Although in Ukraine it is not used. The viability analysis of this channel implementation in the monetary transmission mechanism of Ukraine is executed and the finding about current unavailability for this is made. However, the perspectivity and necessity of asset price channel implementation in the monetary transmission of Ukraine already today requires the creation of theoretic base appropriate for this. Therefore some propositions on the assets price channel implementation in the monetary transmission mechanism of Ukraine are offered.
Keywords: Central Bank, the asset price channel, monetary transmission mechanism, monetary policy, Tobin’s q effect. JEL Classification: Е52, Е58
Assessment of foreign direct investment, export and economic growth on the example of Kazakhstan
Authors: Azatbek Tolkyn , Ramazanov Altay
Published: December 2016

The article considers the problem of estimating the communication of foreign direct investment, net exports and economic growth. As an example, the Republic of Kazakhstan is taken. Based on the method of calculation of the gross domestic product (GDP) expenditure and using the method of regression analysis, the impact of foreign direct investment (FDI) and net exports to GDP and interaction of FDI and net exports as components of GDP are evaluated.
Keywords: investment, FDI, GDP, net exports, economic growth, correlation and regression analysis. JEL Classification: А10, C20, C35, E22, F37, F43
Evaluation of the relative roles of a vegetative filter strip and a biofiltration swale in a treatment train for road runoff
Authors: Flanagan Kelsey , Branchu Philippe , Ramier David , Gromaire Marie-Christine
Published: December 2016

In order to determine the relative importance of a vegetative filter strip and a biofiltration swale in a treatment train for road runoff, US EPA Storm Water Management Model was used to model infiltration and runoff from the filter strip. The model consisted of a series of subcatchments representing the road, the filter strip and the side-slopes of the swale. Simulations were carried out for different rain scenarios representing a variety of climatic conditions. In addition, a sensitivity analysis was conducted for the model's different parameters (soil characteristics and initial humidity, roughness, geometry, etc.). This exercise showed that for the system studied, the majority of road runoff is treated by the filter strip rather than the biofiltration swale, an effect observed especially during periods of low-intensity rainfall. Additionally, it was observed that the combination of infiltration of road runoff in the filter strip and direct rainfall on the system leads to a significant and variable dilution of the runoff reaching the swale. This result has important implications for evaluating the treatment efficiency of the system.