bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 5 from Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
Authors: Morabito Fortunato , Mosca Laura , Cutrona Giovanna , Agnelli Luca , Tuana Giacomo , Ferracin Manuela , Zagatti Barbara , Lionetti Marta , Fabris Sonia , Maura Francesco , Matis Serena , Gentile Massimo , Vigna Ernesto , Colombo Monica , Massucco Carlotta , Recchia Anna Grazia , Bossio Sabrina , De Stefano Laura , Ilariucci Fiorella , Musolino Caterina , Molica Stefano , Di Raimondo Francesco , Cortelezzi Agostino , Tassone Pierfrancesco , Negrini Massimo , Monti Sara , Rossi Davide , Gaidano Gianluca , Ferrarini Manlio , Neri Antonino
Published: April 2023

PDF file - 145K, Q-RT-PCR validation of the microarray expression data of LOC400986 and miR-130a. The microarray and Q-RT-PCR data of LOC400986 (A) and miR-130a (C) scaled in the range 0-1 are shown in the charts together with Pearson correlation coefficient. Boxplots of LOC400986 and miR-130a Q-RT-PCR expression comparing Rai0-CLL vs cMBL cases are represented in charts B and D respectively with the corresponding P-values (Wilcoxon rank sum test).
Supplementary Figures 1 - 5, Tables 1 - 4 from αB-Crystallin: A Novel Regulator of Breast Cancer Metastasis to the Brain
Authors: Malin Dmitry , Strekalova Elena , Petrovic Vladimir , Deal Allison M. , Al Ahmad Abraham , Adamo Barbara , Miller C. Ryan , Ugolkov Andrey , Livasy Chad , Fritchie Karen , Hamilton Erika , Blackwell Kimberly , Geradts Joseph , Ewend Matt , Carey Lisa , Shusta Eric V. , Anders Carey K. , Cryns Vincent L.
Published: April 2023

PDF file - 797K, Figure S1. Barrier phenotype of human brain microvascular endothelial cells and astrocytes in monocultures and co-cultures. Figure S2. alpha/beta-crystallin does not affect cell viability of TNBC cells in standard monolayer culture. Figure S3. alpha/beta-crystallin overexpression increases liver metastases in an orthotopic model of TNBC. Figure S4. Silencing alpha/beta-crystallin inhibits liver metastases in an orthotopic model of TNBC. Figure S5. alpha/beta-crystallin does not affect proliferation or apoptosis in primary mammary tumors and brain metastatic lesions determined at autopsy. Table S1. Patient characteristics Table S2. alpha/beta-crystallin expression in paired tumors. Table S3. Association of alpha/beta-crystallin expression with breast cancer subtype. Table S4. Incidence of metastases in mice in orthotopic models of TNBC .
Supplementary Figure 3 from Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
Authors: Morabito Fortunato , Mosca Laura , Cutrona Giovanna , Agnelli Luca , Tuana Giacomo , Ferracin Manuela , Zagatti Barbara , Lionetti Marta , Fabris Sonia , Maura Francesco , Matis Serena , Gentile Massimo , Vigna Ernesto , Colombo Monica , Massucco Carlotta , Recchia Anna Grazia , Bossio Sabrina , De Stefano Laura , Ilariucci Fiorella , Musolino Caterina , Molica Stefano , Di Raimondo Francesco , Cortelezzi Agostino , Tassone Pierfrancesco , Negrini Massimo , Monti Sara , Rossi Davide , Gaidano Gianluca , Ferrarini Manlio , Neri Antonino
Published: April 2023

PDF file - 289K, Unsupervised analyses in cMBL and Rai0-CLL cases. (A) Gene and (B) miRNA expression profiling analyses by hierarchical clustering. Information about IGHV mutational status ('+' = M, '-' = UM), CD38, ZAP-70, chromosome 12 trisomy, chromosome 17, 11, and 13 deletions ('+' = positive, '-' = negative) are included alongside the patient ID. In the legend bar: turquoise indicates Rai0-CLL and yellow cMBL samples, respectively. The color scale bar represents the relative gene expression changes normalized by the standard deviation, and the color changes in each row represent gene expression relative to the mean across the samples.
Supplementary Figure 2 from Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
Authors: Morabito Fortunato , Mosca Laura , Cutrona Giovanna , Agnelli Luca , Tuana Giacomo , Ferracin Manuela , Zagatti Barbara , Lionetti Marta , Fabris Sonia , Maura Francesco , Matis Serena , Gentile Massimo , Vigna Ernesto , Colombo Monica , Massucco Carlotta , Recchia Anna Grazia , Bossio Sabrina , De Stefano Laura , Ilariucci Fiorella , Musolino Caterina , Molica Stefano , Di Raimondo Francesco , Cortelezzi Agostino , Tassone Pierfrancesco , Negrini Massimo , Monti Sara , Rossi Davide , Gaidano Gianluca , Ferrarini Manlio , Neri Antonino
Published: April 2023

PDF file - 171K, Distribution of unfavorable events in Rai0-CLL and cMBL and correlation with prognosis. (A) Boxplot of concomitant unfavorable events (y-axis)in cMBL and Rai0-CLL; (B) Kaplan-Meier estimated curves of time to first treatment in the whole cohort stratified according to the number of concomitant events (as indicated in each of the four legends). The p-value and the hazard ratios (with the 95% confidence interval) of the proportional hazard model are indicated above each plot.
Supplementary Figure Legends from Stromal Responses among Common Carcinomas Correlated with Clinicopathologic Features
Authors: Chen Julia L-Y. , Espinosa Iñigo , Lin Albert Y. , Liao Olivia Y-W. , van de Rijn Matt , West Robert B.
Published: April 2023

PDF file, 35K.
Supplementary Figure 3 from Stromal Responses among Common Carcinomas Correlated with Clinicopathologic Features
Authors: Chen Julia L-Y. , Espinosa Iñigo , Lin Albert Y. , Liao Olivia Y-W. , van de Rijn Matt , West Robert B.
Published: April 2023

PDF file, 753K, The expression profiles of DTF fibroblast core gene signature in three prostate cancer datasets, including GSE1431 (Supp Fig3A), GSE3933 (Supp Fig3B), and GSE25136 (Supp Fig3C).
Supplementary Methods, Tables 1 - 3 from Identification and Analysis of In Vivo VEGF Downstream Markers Link VEGF Pathway Activity with Efficacy of Anti-VEGF Therapies
Authors: Brauer Matthew J. , Zhuang Guanglei , Schmidt Maike , Yao Jenny , Wu Xiumin , Kaminker Joshua S. , Jurinka Stefanie S. , Kolumam Ganesh , Chung Alicia S. , Jubb Adrian , Modrusan Zora , Ozawa Tomoko , James C. David , Phillips Heidi , Haley Benjamin , Tam Rachel N.W. , Clermont Anne C. , Cheng Jason H. , Yang Sherry X. , Swain Sandra M. , Chen Daniel , Scherer Stefan J. , Koeppen Hartmut , Yeh Ru-Fang , Yue Peng , Stephan Jean-Philippe , Hegde Priti , Ferrara Napoleone , Singh Mallika , Bais Carlos
Published: April 2023

PDF file - 180K, Table S1. Genes in the VDV signature, ordered by anti-VEGF response in human IBC trial. Table S2. Gene Ontology terms over-represented in VDV signature. Table S3. Summary of tumors models tested.
Supplementary Figure 4 from Hsa-miR-31-3p Expression Is Linked to Progression-free Survival in Patients with KRAS Wild-type Metastatic Colorectal Cancer Treated with Anti-EGFR Therapy
Authors: Manceau Gilles , Imbeaud Sandrine , Thiébaut Raphaële , Liébaert François , Fontaine Karine , Rousseau Francis , Génin Bérengère , Corre Delphine Le , Didelot Audrey , Vincent Marc , Bachet Jean-Baptiste , Chibaudel Benoist , Bouché Olivier , Landi Bruno , Bibeau Frédéric , Leroy Karen , Penault-Llorca Frédérique , Van Laethem Jean-Luc , Demetter Pieter , Tejpar Sabine , Rossi Simona , Mosakhani Neda , Österlund Pia , Ristamäki Raija , Sarhadi Virinder , Knuutila Sakari , Boige Valérie , André Thierry , Laurent-Puig Pierre
Published: April 2023

PDF file - 62KB, Kaplan-Meier PFS according to level of expression of hsa-miR-31-3p in the whole series of 132 patients. For the 102 patients who were NRAS wild-type based on Sanger sequencing of exon 2 and 3, the hazard ratio was 2.51 CI95 percent (1.6-4) and the median progression free survival was 10.14 and 35.71 weeks respectively for the high and low risk groups.
Supplementary Figure 4 from Ethacrynic Acid and a Derivative Enhance Apoptosis in Arsenic Trioxide–Treated Myeloid Leukemia and Lymphoma Cells: The Role of Glutathione S-Transferase P1-1
Authors: Wang Rui , Liu Changda , Xia Lijuan , Zhao Guisen , Gabrilove Janice , Waxman Samuel , Jing Yongkui
Published: April 2023

PDF file - 170K, JNK activation leads to Mcl-1 proteasomal degradation
Supplementary Figure 3 from Human Regulatory T Cells Do Not Suppress the Antitumor Immunity in the Bone Marrow: A Role for Bone Marrow Stromal Cells in Neutralizing Regulatory T Cells
Authors: Guichelaar Teun , Emmelot Maarten E. , Rozemuller Henk , Martini Bianka , Groen Richard W.J. , Storm Gert , Lokhorst Henk M. , Martens Anton C. , Mutis Tuna
Published: April 2023

PDF file - 111K, GVHD and GvT regulation in the LME-1 MM tumor model. (A) GvHD scores at weeks 3, 4,and 5. The total score is the sum of the scores for weight loss ( 0=0-10 %; 1=10-20%; 2=>20%. ) , mobility (0= mobile; 1= diminished mobility;2 = immobile) and fur appearance (0=normal; 1= ruffled fur; 2= ruffled fur + red swollen skin; 3= ruffled fur + red swollen skin + patchy alopecia) (B) CD4 and CD8 T cell counts in peripheral blood, BM and spleen at week 3. (C) BLI imaging results of three representative animals per group at week 3. The depicted areas indicate the regions of extramedullar vs medullar tumors . The BLI counts in the corresponding table are in thousands. For each mouse total, extramedullary, and medullary ( total-extramedullary) tumor load are indicated separately. The mean values of the ratio of extramedullary vs medullary tumor load are also depicted.
Supplementary Figure 3 from Ethacrynic Acid and a Derivative Enhance Apoptosis in Arsenic Trioxide–Treated Myeloid Leukemia and Lymphoma Cells: The Role of Glutathione S-Transferase P1-1
Authors: Wang Rui , Liu Changda , Xia Lijuan , Zhao Guisen , Gabrilove Janice , Waxman Samuel , Jing Yongkui
Published: April 2023

PDF file - 124K, Apoptosis protection by antioxidants in HL-60 cells
Supplementary Figure 3 from Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface–Associated GRP78
Authors: Miao Yu Rebecca , Eckhardt Bedrich L. , Cao Yuan , Pasqualini Renata , Argani Pedram , Arap Wadih , Ramsay Robert G. , Anderson Robin L.
Published: April 2023

PDF file - 159K, Supplementary Figure 3. BMTP78 kills breast cell lines in a GRP78-dependent manner.
Supplementary Figure 2 from Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface–Associated GRP78
Authors: Miao Yu Rebecca , Eckhardt Bedrich L. , Cao Yuan , Pasqualini Renata , Argani Pedram , Arap Wadih , Ramsay Robert G. , Anderson Robin L.
Published: April 2023

PDF file - 1974K, Supplementary Figure 2. Antibody against GRP78 protects 4T1.2 cells from BMTP78 but alone has no effect on viability.
Supplementary Table 2 from PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies
Authors: Chen Benjamin J. , Chapuy Bjoern , Ouyang Jing , Sun Heather H. , Roemer Margaretha G.M. , Xu Mina L. , Yu Hongbo , Fletcher Christopher D.M. , Freeman Gordon J. , Shipp Margaret A. , Rodig Scott J.
Published: April 2023

PDF file - 80K, Supplemental Table 2. Pathological Characteristics and PD-L1 Expression in Non-Hodgkin Lymphoma Cases.
Supplementary Figures 1-4 from MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
Authors: Li Ang , Yu Jun , Kim Haeryoung , Wolfgang Christopher L. , Canto Marcia Irene , Hruban Ralph H. , Goggins Michael
Published: April 2023

PDF file - 818K, Supplemental Figure S1 (A) A 3D Principal component analysis (PCA) plot of the miRNA data that characterizes the trends exhibited by the expression profiles of pancreatic cancer (PC, purple), pancreatic neuroendocrine tumor (NET, green), chronic pancreatitis (CP, red)), healthy controls (N, blue). Each dot represents a sample and each color represents the type of the sample. (B) VENN diagram showing significantly elevated miRNAs (fold-change less than or equal to 2 and p<0.05) in pancreatic cancer (PC) compared to three control groups (NET, CP, and N). Supplemental Figure S2 Reproducibility of Taqman miRNA microarray. (A) A serum sample was analyzed in duplicate and the correlation was determined using Spearman test. (B) The effects of pre-amplification on serum miR-1290 levels by Taqman RT-PCR. Supplemental Figure S3 Validation of elevated miRNAs in serum from patients with pancreatic cancer. Levels of selected serum microRNAs were compared in an independent set of cases and controls including patients with pancreatic cancer (n=41) compared to patients with pancreatic neuroendocrine tumor (NET) (n=18) and chronic pancreatitis (CP) (n=35), normal controls (N) (n=19), and the combined from of non-malignant controls including chronic pancreatitis and normal controls (CN) (n=54), and non-pancreatic cancer control including pancreatic neuroendocrine tumor, chronic pancreatitis, and normal controls (NCN) (n=72) using Taqman real-time PCR. Boxes represent the inter-quartile range and the line indicates the median value. Error bars indicate the 90th and 10th percentiles. MiR-16 was used as reference gene for normalization. Mann-Whitney was used to compare groups. 2 Supplemental Figure S4 The effects of miR-1290 on pancreatic cancer cell proliferation and invasion. (A). The expression levels of miR-1290 were measured in miR-1290 mimic-transfected AsPC1 and Panc5.04 and miR-1290 inhibitor-transfected Panc10.05 and Panc198 cell lines, respectively. (B). Cell lines expressing low levels of miR 1290 (AsPC1 and Panc5.04) were transfected with miR-1290 mimic and cell lines with high miR-1290 (Panc10.05 and Panc198) were transfected with a miR-1290 inhibitor and miRNA controls, and cell growth was determined using MTS assay, respectively. Data are mean +/- SD of 5 replicates and are representative of two independent experiments. (C). The invasive potential of miR-1290 was determined using a chamber matrigel invasion assay in the same cell lines treated in the same way. Data are mean +/- SD of triplicates and are representative of two independent experiments. Representative photographs of invasion assays were shown (D). Original magnification, 20x.
Supplementary Figure 2 from Targeting the CD20 and CXCR4 Pathways in Non-Hodgkin Lymphoma with Rituximab and High-Affinity CXCR4 Antagonist BKT140
Authors: Beider Katia , Ribakovsky Elena , Abraham Michal , Wald Hanna , Weiss Lola , Rosenberg Evgenia , Galun Eithan , Avigdor Abraham , Eizenberg Orly , Peled Amnon , Nagler Arnon
Published: April 2023

Supplementary Figure 2 - PDF file 64K, CXCR4 migratory function in NHL cells
Supplementary Figure 7 from Role of Hedgehog Signaling in Malignant Pleural Mesothelioma
Authors: Shi Yandong , Moura Ubiratan , Opitz Isabelle , Soltermann Alex , Rehrauer Hubert , Thies Svenja , Weder Walter , Stahel Rolf A. , Felley-Bosco Emanuela
Published: April 2023

PDF file, 159K, HHIP protein is expressed in all tumor cells and its levels are increased by HhAntag. Immunohistochemistry analysis of HHIP expression was performed on xenograft tumors of control and HhAntag treated mice. H score was determined based as frequency* intensity ( frequency score 1=1-10% cells, 2=11-50% cells, 3=51-100% cells and intensity score1=low; 2= high). Bar represents 50 μm.
Supplementary Figure 4 from Role of Hedgehog Signaling in Malignant Pleural Mesothelioma
Authors: Shi Yandong , Moura Ubiratan , Opitz Isabelle , Soltermann Alex , Rehrauer Hubert , Thies Svenja , Weder Walter , Stahel Rolf A. , Felley-Bosco Emanuela
Published: April 2023

PDF file, 52K, Downregulation of GLI1 target HHIP after treatment of MPM cells during 48h with HhAntag 5 μM.
Supplementary Figure 3 from Role of Hedgehog Signaling in Malignant Pleural Mesothelioma
Authors: Shi Yandong , Moura Ubiratan , Opitz Isabelle , Soltermann Alex , Rehrauer Hubert , Thies Svenja , Weder Walter , Stahel Rolf A. , Felley-Bosco Emanuela
Published: April 2023

PDF file, 117K, Quantitative real-time PCR analysis of HH pathway gene expression in primary cultures grown without serum and 3% oxygen (n=15).
Table S2 from Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non–Small Cell Lung Cancer
Authors: Sun Nan , Chen Zhaoli , Tan Fengwei , Zhang Baihua , Yao Ran , Zhou Chengcheng , Li Jiagen , Gao Yibo , Liu Ziyuan , Tan Xiaogang , Zhou Fang , He Max Y.F , Shao Kang , Li Ning , Qiu Bin , Sun Jian , Yu Yue , Wang Suya , Zhao Yuda , Shi Xuejiao , He Jie
Published: April 2023

The analysis of the Pearson Correlation between IDH1 levels and smoking history in ADC, SCC, and healthy control groups.
Supplementary Figure legend from Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non–Small Cell Lung Cancer
Authors: Sun Nan , Chen Zhaoli , Tan Fengwei , Zhang Baihua , Yao Ran , Zhou Chengcheng , Li Jiagen , Gao Yibo , Liu Ziyuan , Tan Xiaogang , Zhou Fang , He Max Y.F , Shao Kang , Li Ning , Qiu Bin , Sun Jian , Yu Yue , Wang Suya , Zhao Yuda , Shi Xuejiao , He Jie
Published: April 2023

The legend of Figure S1
Supplementary Video 2 from PD-L1 on Tumor Cells Is Induced in Ascites and Promotes Peritoneal Dissemination of Ovarian Cancer through CTL Dysfunction
Authors: Abiko Kaoru , Mandai Masaki , Hamanishi Junzo , Yoshioka Yumiko , Matsumura Noriomi , Baba Tsukasa , Yamaguchi Ken , Murakami Ryusuke , Yamamoto Ayaka , Kharma Budiman , Kosaka Kenzo , Konishi Ikuo
Published: April 2023

AVI file - 3239K, Video S2 is a time-lapse videos showing GFP-positive CTLs attacking ID8-pdl1 obtained by time-lapse fluorescence microscopy. Methods of the cell preparation are described in the Materials and Methods section. Total time; 136 minutes, the frame rate; 2 minutes, display rate; 10 frames/second. Fig. 4G is related to this video.
Supplementary Text. from Clinical Activity and Safety of Combination Therapy with Temsirolimus and Bevacizumab for Advanced Melanoma: A Phase II Trial (CTEP 7190/Mel47)
Authors: Slingluff Craig L. , Petroni Gina R. , Molhoek Kerrington R. , Brautigan David L. , Chianese-Bullock Kimberly A. , Shada Amber L. , Smolkin Mark E. , Olson Walter C. , Gaucher Alison , Chase Cheryl Murphy , Grosh William W. , Weiss Geoffrey R. , Wagenseller Aubrey G. , Olszanski Anthony J. , Martin Lainie , Shea Sofia M. , Erdag Gulsun , Ram Prahlad , Gershenwald Jeffrey E. , Weber Michael J.
Published: April 2023

Supplemental text for Methods and Results.
Supplementary Table 1 from PD-L1 on Tumor Cells Is Induced in Ascites and Promotes Peritoneal Dissemination of Ovarian Cancer through CTL Dysfunction
Authors: Abiko Kaoru , Mandai Masaki , Hamanishi Junzo , Yoshioka Yumiko , Matsumura Noriomi , Baba Tsukasa , Yamaguchi Ken , Murakami Ryusuke , Yamamoto Ayaka , Kharma Budiman , Kosaka Kenzo , Konishi Ikuo
Published: April 2023

XLSX file - 80K, Table S1 shows characteristics of patients in KOV-IH-65 and KOV-MA-64.
Supplementary Figure 2 from A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non–Small Cell Lung Cancer Patients
Authors: Tang Hao , Xiao Guanghua , Behrens Carmen , Schiller Joan , Allen Jeffrey , Chow Chi-Wan , Suraokar Milind , Corvalan Alejandro , Mao Jianhua , White Michael A. , Wistuba Ignacio I. , Minna John D. , Xie Yang
Published: April 2023

PDF file - 200K, Summary of the prognostic performance for the 12 hub-gene set.
Supplemental Table 3 from Direct Evidence of Target Inhibition with Anti-VEGF, EGFR, and mTOR Therapies in a Clinical Model of Wound Healing
Authors: Jia Jingquan , Dellinger Andrew E. , Weiss Eric S. , Bulusu Anuradha , Rushing Christel , Li Haiyan , Howard Leigh A. , Kaplan Neal , Pang Herbert , Hurwitz Herbert I. , Nixon Andrew B.
Published: April 2023

Supplemental Table 3. BEP study patients and the number of patients whose granulation tissue biopsies were available for biomarker study.
Supplementary Figure Legend from BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice
Authors: Liu Chengwen , Peng Weiyi , Xu Chunyu , Lou Yanyan , Zhang Minying , Wargo Jennifer A. , Chen Jie Qing , Li Haiyan S. , Watowich Stephanie S. , Yang Yan , Frederick Dennie Tompers , Cooper Zachary A. , Mbofung Rina M. , Whittington Mayra , Flaherty Keith T. , Woodman Scott E. , Davies Michael A. , Radvanyi Laszlo G. , Overwijk Willem W. , Lizée Gregory , Hwu Patrick
Published: April 2023

PDF file - 95K
Data Supplement from T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness
Authors: Pinto Filipe , Pértega-Gomes Nelma , Pereira Márcia S. , Vizcaíno José R. , Monteiro Pedro , Henrique Rui M. , Baltazar Fátima , Andrade Raquel P. , Reis Rui M.
Published: April 2023

Supplementary Figure S4. Brachyury overexpression in DU145 metastatic cell line increases prostate cancer cell aggressiveness.
Supplementary Figure 7 from BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice
Authors: Liu Chengwen , Peng Weiyi , Xu Chunyu , Lou Yanyan , Zhang Minying , Wargo Jennifer A. , Chen Jie Qing , Li Haiyan S. , Watowich Stephanie S. , Yang Yan , Frederick Dennie Tompers , Cooper Zachary A. , Mbofung Rina M. , Whittington Mayra , Flaherty Keith T. , Woodman Scott E. , Davies Michael A. , Radvanyi Laszlo G. , Overwijk Willem W. , Lizée Gregory , Hwu Patrick
Published: April 2023

PDF file - 72K, PLX4720 treatment does not increase infiltration of adoptively transferred T cells into tumors containing WT BRAF
Supplementary Figure 6 from BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice
Authors: Liu Chengwen , Peng Weiyi , Xu Chunyu , Lou Yanyan , Zhang Minying , Wargo Jennifer A. , Chen Jie Qing , Li Haiyan S. , Watowich Stephanie S. , Yang Yan , Frederick Dennie Tompers , Cooper Zachary A. , Mbofung Rina M. , Whittington Mayra , Flaherty Keith T. , Woodman Scott E. , Davies Michael A. , Radvanyi Laszlo G. , Overwijk Willem W. , Lizée Gregory , Hwu Patrick
Published: April 2023

PDF file - 82K, Administration of PLX4720 in vivo increases tumor infiltration of adoptively transferred T cells and enhances antitumor responses
Data Supplement from Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
Authors: Suryani Santi , Carol Hernan , Chonghaile Triona Ni , Frismantas Viktoras , Sarmah Chintanu , High Laura , Bornhauser Beat , Cowley Mark J. , Szymanska Barbara , Evans Kathryn , Boehm Ingrid , Tonna Elise , Jones Luke , Manesh Donya Moradi , Kurmasheva Raushan T. , Billups Catherine , Kaplan Warren , Letai Anthony , Bourquin Jean-Pierre , Houghton Peter J. , Smith Malcolm A. , Lock Richard B.
Published: April 2023

Supplementary Figures S6-S9. Correlations between BCL2 family gene expression and in vivo ABT-263 sensitivity in the MLL-ALL xenograft panel; S7. Correlations between BCL2 family gene expression and in vivo ABT-263 sensitivity in the BCP-ALL xenograft panel; S8. Correlations between BCL2 family gene expression and in vivo ABT-263 sensitivity in the T-ALL xenograft panel; S9. Representative immunoblot of MCL1 protein expression in ALL xenografts.
Supplementary Figure 1 from Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients
Authors: Aarntzen Erik H. J. G. , Schreibelt Gerty , Bol Kalijn , Lesterhuis W. Joost , Croockewit Alexandra J. , de Wilt Johannes H. W. , van Rossum Michelle M. , Blokx Willeke A. M. , Jacobs Joannes F. M. , Duiveman-de Boer Tjitske , Schuurhuis Danita H. , Mus Roel , Thielemans Kris , de Vries I. Jolanda M. , Figdor Carl G. , Punt Cornelis J. A. , Adema Gosse J.
Published: April 2023

PDF file, 149K, CONSORT flow chart.
Supplementary Table S6 from Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study
Authors: Frantzi Maria , van Kessel Kim E. , Zwarthoff Ellen C. , Marquez Mirari , Rava Marta , Malats Núria , Merseburger Axel S. , Katafigiotis Ioannis , Stravodimos Konstantinos , Mullen William , Zoidakis Jerome , Makridakis Manousos , Pejchinovski Martin , Critselis Elena , Lichtinghagen Ralph , Brand Korbinian , Dakna Mohammed , Roubelakis Maria G. , Theodorescu Dan , Vlahou Antonia , Mischak Harald , Anagnou Nicholas P.
Published: April 2023

Supplementary Table S6. Multivariate analysis for investigating the comparative performance of the biomarker classifier and cytology for detecting recurrence. Of the 211 subjects that were included in the validation phase, voided urinary cytology (VUC) results were available for 96 urinary samples.
Supplementary Table S2 from Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study
Authors: Frantzi Maria , van Kessel Kim E. , Zwarthoff Ellen C. , Marquez Mirari , Rava Marta , Malats Núria , Merseburger Axel S. , Katafigiotis Ioannis , Stravodimos Konstantinos , Mullen William , Zoidakis Jerome , Makridakis Manousos , Pejchinovski Martin , Critselis Elena , Lichtinghagen Ralph , Brand Korbinian , Dakna Mohammed , Roubelakis Maria G. , Theodorescu Dan , Vlahou Antonia , Mischak Harald , Anagnou Nicholas P.
Published: April 2023

Supplementary Table S2. Clinical and demographical data for the urine samples (n= 636) from recurrent UBC patients, categorized in the discovery (n=425) and validation phase (n=211). The distribution of the patients which previously received additional treatment in the discovery and validation set is also shown (n=371 patients).
Supplemental Information, Supplementary Tables 1-2 from Methionine and Kynurenine Activate Oncogenic Kinases in Glioblastoma, and Methionine Deprivation Compromises Proliferation
Authors: Palanichamy Kamalakannan , Thirumoorthy Krishnan , Kanji Suman , Gordon Nicolaus , Singh Rajbir , Jacob John R. , Sebastian Nikhil , Litzenberg Kevin T. , Patel Disha , Bassett Emily , Ramasubramanian Brinda , Lautenschlaeger Tim , Fischer Steven M. , Ray-Chaudhury Abhik , Chakravarti Arnab
Published: April 2023

Additional Supporting Information
Supplementary Figure Legend from Dysregulation of the Repressive H3K27 Trimethylation Mark in Head and Neck Squamous Cell Carcinoma Contributes to Dysregulated Squamous Differentiation
Authors: Gannon Orla M. , Merida de Long Lilia , Endo-Munoz Liliana , Hazar-Rethinam Mehlika , Saunders Nicholas A.
Published: April 2023

PDF file - 130K
supplemental figure legend from Manipulating the Tumor Microenvironment Ex Vivo for Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
Authors: Chacon Jessica Ann , Sarnaik Amod A. , Chen Jie Qing , Creasy Caitlin , Kale Charuta , Robinson John , Weber Jeffrey , Hwu Patrick , Pilon-Thomas Shari , Radvanyi Laszlo
Published: April 2023

supplemental figure legend
Supplemental Table 1 from MHC Class I Loss Is a Frequent Mechanism of Immune Escape in Papillary Thyroid Cancer That Is Reversed by Interferon and Selumetinib Treatment In Vitro
Authors: Angell Trevor E. , Lechner Melissa G. , Jang Julie K. , LoPresti Jonathan S. , Epstein Alan L.
Published: April 2023

Supplemental Table 1. Primer sequences for qRT-PCR. Forward and reverse primer sequences are shown for each gene examined, in 5' to 3' direction.
Supplemental Figures 1-8 from The Prognostic Impact of CD163-Positive Macrophages in Follicular Lymphoma: A Study from the BC Cancer Agency and the Lymphoma Study Association
Authors: Kridel Robert , Xerri Luc , Gelas-Dore Bénédicte , Tan King , Feugier Pierre , Vawda Ayesha , Canioni Danielle , Farinha Pedro , Boussetta Sami , Moccia Alden A. , Brice Pauline , Chavez Elizabeth A. , Kyle Alastair H. , Scott David W. , Sanders Ashley D. , Fabiani Bettina , Slack Graham W. , Minchinton Andrew I. , Haioun Corinne , Connors Joseph M. , Sehn Laurie H. , Steidl Christian , Gascoyne Randy D. , Salles Gilles
Published: April 2023

Supplemental Figures 1-8. Suppl. Fig 1. Consort flow diagram. Shown are patient numbers throughout the study. The BCCA TMA was built as duplicate 1.5mm cores whereas the PRIMA TMA was built as triplicate 1.0mm cores. Strict QC criteria were applied to each sample to increase accuracy of point estimates for macrophage infiltration. We required each sample to be represented by more than 1 core, to be unequivocally attributable to a patient and the relative standard error to be less than 33.33%. Suppl. Fig 2. Correlation between Aperio and manual scoring in the BCCA cohort for CD68 (left) and CD163 (right). Suppl. Fig 3. Representative microscopy images in low power magnification. (A) Immunohistochemistry using anti-human CD68 (clone KP1) and anti-human CD163 (clone 10D6) for case FL124 (average number of macrophages). (B) Similar images for case FL136 (elevated number of macrophages). Suppl. Fig 4. (A) Distribution of CD68 and CD163 scores in the BCCA and PRIMA cohorts. (B) Double immunofluorescence on formalin-fixed and paraffin-embedded tissue using antibodies against CD68 and CD163. Shown is case FL148 (22.64% CD68 positive pixels and 4.39% CD163 positive pixels by Aperio). Suppl. Fig 5. Distribution of CD68 and CD163 in the BCCA and PRIMA cohorts. Suppl. Fig 6. Correlation between CD68 and CD163 in the BCCA (left) and PRIMA cohorts (right). Suppl. Fig 7. Outcome correlation for CD68 in the BCCA cohort. The most significant cut-off of 2.94% was defined for progression-free survival (PFS) in the training cohort and carried forward into the overall survival (OS) analysis and validation cohorts. PFS and OS are calculated from date of initiation of R-CVP. Suppl. Fig 8. Outcome correlation for CD68 in the PRIMA cohort. The optimal cut-off of 1.41 was defined for progression-free survival (PFS) in the training cohort and carried forward into the overall survival (OS) analysis and validation cohorts. PFS and OS are calculated from date of registration in the trial.
Data Supplement from Decreased Expression of miR216a Contributes to Non–Small-Cell Lung Cancer Progression
Authors: Wang Ren-Tao , Xu Meng , Xu Cheng-Xiong , Song Zhi-Gang , Jin Hua
Published: April 2023

Supplementary figure legends
Supplementary Table S6 from The Ability of Bilirubin in Identifying Smokers with Higher Risk of Lung Cancer: A Large Cohort Study in Conjunction with Global Metabolomic Profiling
Authors: Wen Chi-Pang , Zhang Fanmao , Liang Dong , Wen Christopher , Gu Jian , Skinner Heath , Chow Wong-Ho , Ye Yuanqing , Pu Xia , Hildebrandt Michelle A.T. , Huang Maosheng , Chen Chien-Hua , Hsiung Chao Agnes , Tsai Min Kuang , Tsao Chwen Keng , Lippman Scott M. , Wu Xifeng
Published: April 2023

Supplementary Table S6. Relationship among smoking, bilirubin levels and risk for lung cancer incidence/mortality in female participants of the prospective cohort study
Supplementary Methods from The Ability of Bilirubin in Identifying Smokers with Higher Risk of Lung Cancer: A Large Cohort Study in Conjunction with Global Metabolomic Profiling
Authors: Wen Chi-Pang , Zhang Fanmao , Liang Dong , Wen Christopher , Gu Jian , Skinner Heath , Chow Wong-Ho , Ye Yuanqing , Pu Xia , Hildebrandt Michelle A.T. , Huang Maosheng , Chen Chien-Hua , Hsiung Chao Agnes , Tsai Min Kuang , Tsao Chwen Keng , Lippman Scott M. , Wu Xifeng
Published: April 2023

Supplementary Methods. Serum total bilirubin levels and lung cancer incidence and mortality rates in overall males and male smokers
Supplemental Table S2 from On-Target Effect of FK866, a Nicotinamide Phosphoribosyl Transferase Inhibitor, by Apoptosis-Mediated Death in Chronic Lymphocytic Leukemia Cells
Authors: Gehrke Iris , Bouchard Eric D.J. , Beiggi Sara , Poeppl Armando G. , Johnston James B. , Gibson Spencer B. , Banerji Versha
Published: April 2023

Table S2: The associations between patient characteristics (Table S1, columns 2 to 11), patient treatment (Tx) status (Table S1, column 12) and sensitivity to FK866 based on LD50 (Table S1, column 13) were measured using Fisher's Exact Test of Independence and univariable logistic regression analysis. For Fisher's Exact Test two different LD50 cut off values (8 nM and 14 nM) were used to generate two groups based on sensitivity to FK866. Analyses were performed using SAS 9.2. WBC: white blood count, LDT: lymphocyte doubling time, B2M: β2-microglobulin, IgVh: immunoglobulin variable heavy chain, del17p13.1: deletion 17p13.1, OR: Odds ratio, CI: confidence interval. Tx: treatment
Data Supplement from SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic Malignancies
Authors: Deckert Jutta , Wetzel Marie-Cécile , Bartle Laura M. , Skaletskaya Anna , Goldmacher Victor S. , Vallée François , Zhou-Liu Qing , Ferrari Paul , Pouzieux Stéphanie , Lahoute Charlotte , Dumontet Charles , Plesa Adriana , Chiron Marielle , Lejeune Pascale , Chittenden Thomas , Park Peter U. , Blanc Véronique
Published: April 2023

Supplementary Figure S1. SAR650984 binding and activity on normal human blood cells
Supplemental Figure 1 from MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking
Authors: Arcila Maria E. , Drilon Alexander , Sylvester Brooke E. , Lovly Christine M. , Borsu Laetitia , Reva Boris , Kris Mark G. , Solit David B. , Ladanyi Marc
Published: April 2023

Supplemental Figure 1. The F53L, Q56P, K57N and D67N mutants were sensitive to MEK inhibition when treated with the 1 ÃŽÂ¼M of the MEK inhibitor Selumetinib (AZD6244). ERK activation decreased significantly after 30 minutes of treatment.
Supplementary Figure Legend from Milatuzumab-Conjugated Liposomes as Targeted Dexamethasone Carriers for Therapeutic Delivery in CD74+ B-cell Malignancies
Authors: Mao Yicheng , Triantafillou Georgia , Hertlein Erin , Towns William , Stefanovski Matthew , Mo Xiaokui , Jarjoura David , Phelps Mitch , Marcucci Guido , Lee Ly James , Goldenberg David M. , Lee Robert J. , Byrd John C. , Muthusamy Natarajan
Published: April 2023

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Supplementary figure 3 from Tadalafil Reduces Myeloid-Derived Suppressor Cells and Regulatory T Cells and Promotes Tumor Immunity in Patients with Head and Neck Squamous Cell Carcinoma
Authors: Weed Donald T. , Vella Jennifer L. , Reis Isildinha M. , De la fuente Adriana C. , Gomez Carmen , Sargi Zoukaa , Nazarian Ronen , Califano Joseph , Borrello Ivan , Serafini Paolo
Published: April 2023

Supplementary figure 3. Tumor micro-environment modulation according to dose categories
Figure S3 from Acquisition of Relative Interstrand Crosslinker Resistance and PARP Inhibitor Sensitivity in Fanconi Anemia Head and Neck Cancers
Authors: Lombardi Anne J. , Hoskins Elizabeth E. , Foglesong Grant D. , Wikenheiser-Brokamp Kathryn A. , Wiesmüller Lisa , Hanenberg Helmut , Andreassen Paul R. , Jacobs Allison J. , Olson Susan B. , Keeble Winifred W. , Hays Laura E. , Wells Susanne I.
Published: April 2023

Figure S3. Effect of DNA-PKcs inhibition on cisplatin sensitivity of HNSCC cells
Supplementary Figures from Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors
Authors: Varešlija Damir , McBryan Jean , Fagan Ailís , Redmond Aisling M. , Hao Yuan , Sims Andrew H. , Turnbull Arran , Dixon J.M. , Ó Gaora Peadar , Hudson Lance , Purcell Siobhan , Hill Arnold D.K. , Young Leonie S.
Published: April 2023

Figure S1. Ligand independent ER drives growth of AI resistant cells. Figure S2. Confirmation of transient knockdown using siRNA. Figure S3: pSer118 ER expression significantly increases during neoadjuvant AI therapy. Figure S4: Androgen Receptor (AR) expression in patient tumours before and after endocrine therapy. Figure S5. Reduced ligand dependency is a feature of multiple endocrine resistant cells compared to endocrine sensitive MCF7 cells. Figure S6. FoxA1 expression and interactions with ER are comparable between MCF7 and LetR cells treated with either estrogen (E2) or androstenedione (A). Figure S7. Steroid-sensitive recruitment of ER to a selection of target genes in MCF7-Aro cells. q-PCR of ER ChIP in MCF7-Aro cells treated with vehicle (V) or steroid (S) for 45 minutes. IgG was used as an internal control. Bar charts show relative recruitment to each target gene with n=3. Heat map shows relative recruitment of ER to each target gene as a fold increase above IgG control. Figure S8. ER ChIPseq binding peak profiles in 7 genes of the ER target gene signature. ER binding activity is observed at the same location in both LY2 and LetR cells. Images were captured from UCSC Genome Browser. V, vehicle; E, estrogen; A, androstenedione. Figure S9. ER binding does not affect expression of PEBP4. Figure S10. A, EGR3 knockdown decreases cell growth in LetR cells. Figure S11: ER target gene signature is more accurate than ESR1 alone for predicting outcome on AI therapy.
Data Supplement from An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non–Small Cell Lung Cancer
Authors: Noguchi Satoshi , Saito Akira , Horie Masafumi , Mikami Yu , Suzuki Hiroshi I. , Morishita Yasuyuki , Ohshima Mitsuhiro , Abiko Yoshimitsu , Mattsson Johanna Sofia Margareta , König Helena , Lohr Miriam , Edlund Karolina , Botling Johan , Micke Patrick , Nagase Takahide
Published: April 2023

Supplementary Figure S5. Amphiregulin protein expression in NSCLC.
Supplementary Figure S3 from Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Authors: Fjeldbo Christina S. , Julin Cathinka H. , Lando Malin , Forsberg Malin F. , Aarnes Eva-Katrine , Alsner Jan , Kristensen Gunnar B. , Malinen Eirik , Lyng Heidi
Published: April 2023

Comparing classification based on Illumina and RT-qPCR assay.
Supplementary Figure Legend from Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy
Authors: Wheeler Heather E. , Gamazon Eric R. , Wing Claudia , Njiaju Uchenna O. , Njoku Chidiamara , Baldwin Robert Michael , Owzar Kouros , Jiang Chen , Watson Dorothy , Shterev Ivo , Kubo Michiaki , Zembutsu Hitoshi , Winer Eric P. , Hudis Clifford A. , Shulman Lawrence N. , Nakamura Yusuke , Ratain Mark J. , Kroetz Deanna L. , Cox Nancy J. , Dolan Mary Eileen
Published: April 2023

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Supplementary Figure 5 from MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research
Authors: Chang Wendy , Brohl Andrew S. , Patidar Rajesh , Sindiri Sivasish , Shern Jack F. , Wei Jun S. , Song Young K. , Yohe Marielle E. , Gryder Berkley , Zhang Shile , Calzone Kathleen A. , Shivaprasad Nityashree , Wen Xinyu , Badgett Thomas C. , Miettinen Markku , Hartman Kip R. , League-Pascual James C. , Trahair Toby N. , Widemann Brigitte C. , Merchant Melinda S. , Kaplan Rosandra N. , Lin Jimmy C. , Khan Javed
Published: April 2023

Schema for planned genomics guided CLIA sequencing program (ClinOmics) for the Center for Cancer Research of the intramural National Cancer Institute.
Supplementary Figure 1 from MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research
Authors: Chang Wendy , Brohl Andrew S. , Patidar Rajesh , Sindiri Sivasish , Shern Jack F. , Wei Jun S. , Song Young K. , Yohe Marielle E. , Gryder Berkley , Zhang Shile , Calzone Kathleen A. , Shivaprasad Nityashree , Wen Xinyu , Badgett Thomas C. , Miettinen Markku , Hartman Kip R. , League-Pascual James C. , Trahair Toby N. , Widemann Brigitte C. , Merchant Melinda S. , Kaplan Rosandra N. , Lin Jimmy C. , Khan Javed
Published: April 2023

Flowcharts of filtering criteria. A. Flowchart of filtering criteria for germline variants, B. Flowchart of filtering criteria for somatic variants
Supplementary Figure 3 from Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer
Authors: Julien Sylvia , Merino-Trigo Ana , Lacroix Ludovic , Pocard Marc , Goéré Diane , Mariani Pascale , Landron Sophie , Bigot Ludovic , Nemati Fariba , Dartigues Peggy , Weiswald Louis-Bastien , Lantuas Denis , Morgand Loïc , Pham Emmanuel , Gonin Patrick , Dangles-Marie Virginie , Job Bastien , Dessen Philippe , Bruno Alain , Pierré Alain , De Thé Hugues , Soliman Hany , Nunes Manoel , Lardier Guillaume , Calvet Loreley , Demers Brigitte , Prévost Grégoire , Vrignaud Patricia , Roman-Roman Sergio , Duchamp Olivier , Berthet Cyril
Published: April 2023

PDF file, 67K, Hierarchical clustering of 82 tumors based on Chromosomal abnormalities analyzed by 244k aCGH.
Data Supplement from Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History
Authors: Karlsson Anna , Ringnér Markus , Lauss Martin , Botling Johan , Micke Patrick , Planck Maria , Staaf Johan
Published: April 2023

Supplementary Figure S2. Detailed results of supervised classification of smoking status in adenocarcinoma gene expression microarray cohorts.
Supplementary Figure 2 from Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer
Authors: Julien Sylvia , Merino-Trigo Ana , Lacroix Ludovic , Pocard Marc , Goéré Diane , Mariani Pascale , Landron Sophie , Bigot Ludovic , Nemati Fariba , Dartigues Peggy , Weiswald Louis-Bastien , Lantuas Denis , Morgand Loïc , Pham Emmanuel , Gonin Patrick , Dangles-Marie Virginie , Job Bastien , Dessen Philippe , Bruno Alain , Pierré Alain , De Thé Hugues , Soliman Hany , Nunes Manoel , Lardier Guillaume , Calvet Loreley , Demers Brigitte , Prévost Grégoire , Vrignaud Patricia , Roman-Roman Sergio , Duchamp Olivier , Berthet Cyril
Published: April 2023

PDF file, 241K, Frequency of abnormalities detected by aCGH among all samples tested across the genome.
Data Supplement from Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History
Authors: Karlsson Anna , Ringnér Markus , Lauss Martin , Botling Johan , Micke Patrick , Planck Maria , Staaf Johan
Published: April 2023

Supplementary Figure S4. Molecular and clinicopathological characteristics of adenocarcinoma consensus clusters in microarray and TCGA cohorts with respect to patient smoking history.
Data Supplement from Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History
Authors: Karlsson Anna , Ringnér Markus , Lauss Martin , Botling Johan , Micke Patrick , Planck Maria , Staaf Johan
Published: April 2023

Legends for supplementary figures and tables.
Data Supplement from Functional Genetic Approach Identifies MET, HER3, IGF1R, INSR Pathways as Determinants of Lapatinib Unresponsiveness in HER2-Positive Gastric Cancer
Authors: Zhang Zhe , Wang Jiping , Ji Dongmei , Wang Chenchen , Liu Rujiao , Wu Zheng , Liu Lian , Zhu Dan , Chang Jinjia , Geng Ruixuan , Xiong Lei , Fang Qiangyi , Li Jin
Published: April 2023

Supplementary Figure 4. HER3 Signaling Activation Attenuates Lapatinib-induced Apoptosis and Suppression of cell motility
Supplementary Table 1 from Cytoplasmic Accumulation of Sequestosome 1 (p62) Is a Predictor of Biochemical Recurrence, Rapid Tumor Cell Proliferation, and Genomic Instability in Prostate Cancer
Authors: Burdelski Christoph , Reiswich Viktor , Hube-Magg Claudia , Kluth Martina , Minner Sarah , Koop Christina , Graefen Markus , Heinzer Hans , Tsourlakis Maria Christina , Wittmer Corinna , Huland Hartwig , Simon Ronald , Schlomm Thorsten , Sauter Guido , Steurer Stefan
Published: April 2023

Supplementary Table 1. Composition of the prognosis tissue microarray containing 12,427 prostate cancer specimens
Supplementary Tables 1-6 from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Authors: Guerzoni Clara , Fiori Valentina , Terracciano Mario , Manara Maria Cristina , Moricoli Diego , Pasello Michela , Sciandra Marika , Nicoletti Giordano , Gellini Mara , Dominici Sabrina , Chiodoni Claudia , Fornasari Pier Maria , Lollini Pier-Luigi , Colombo Mario P. , Picci Piero , Cianfriglia Maurizio , Magnani Mauro , Scotlandi Katia
Published: April 2023

Supplementary Table S1: Efficacy of anti-CD99 mAb 0662 in a panel of EWS cell lines Supplementary Table S2: Fold induction/reduction of gene expression in treated samples over control mRNAs, analyzed with F-statistic (error <5%). Supplementary Table S3: Fold induction/reduction of protein expression in 5 min treated samples over control Supplementary Table S4: Ratio of firefly and Renilla luciferase signals in Saos-2 p53 deficient cell line co-transfected with a p53-reporter plasmid (pG13-LUC) and pCDNA3.1-E.V., pcDNA3.1-p53WT or mutant pcDNA3.1- p53S241F. Supplementary Table S5: Evaluation of NK number and activity in the four mice groups. Supplementary Table S6: Mice weight and blood parameters of mice from control or treated groups.
Data Supplement from GSK-3β–Regulated N-Acetyltransferase 10 Is Involved in Colorectal Cancer Invasion
Authors: Zhang Hong , Hou Wei , Wang Hua-Li , Liu Hai-Jing , Jia Xin-Ying , Zheng Xing-Zheng , Zou Yong-Xin , Li Xin , Hou Lin , McNutt Michael A. , Zhang Bo
Published: April 2023

Supplementary Figure S1. The immunostaining of NAT10 and β-catenin in metastatic CRCs.
Supplementary Methods from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Authors: Guerzoni Clara , Fiori Valentina , Terracciano Mario , Manara Maria Cristina , Moricoli Diego , Pasello Michela , Sciandra Marika , Nicoletti Giordano , Gellini Mara , Dominici Sabrina , Chiodoni Claudia , Fornasari Pier Maria , Lollini Pier-Luigi , Colombo Mario P. , Picci Piero , Cianfriglia Maurizio , Magnani Mauro , Scotlandi Katia
Published: April 2023

Supplementary Methods from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Supplementary Figure 6 from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Authors: Guerzoni Clara , Fiori Valentina , Terracciano Mario , Manara Maria Cristina , Moricoli Diego , Pasello Michela , Sciandra Marika , Nicoletti Giordano , Gellini Mara , Dominici Sabrina , Chiodoni Claudia , Fornasari Pier Maria , Lollini Pier-Luigi , Colombo Mario P. , Picci Piero , Cianfriglia Maurizio , Magnani Mauro , Scotlandi Katia
Published: April 2023

HSP70 levels are unaffected from dAbd C7 treatment.
Supplementary Figure 4 from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Authors: Guerzoni Clara , Fiori Valentina , Terracciano Mario , Manara Maria Cristina , Moricoli Diego , Pasello Michela , Sciandra Marika , Nicoletti Giordano , Gellini Mara , Dominici Sabrina , Chiodoni Claudia , Fornasari Pier Maria , Lollini Pier-Luigi , Colombo Mario P. , Picci Piero , Cianfriglia Maurizio , Magnani Mauro , Scotlandi Katia
Published: April 2023

dAbd C7 activity is related to p53 status, but is ineffective in h-MSC cells.
Supplementary Figure 3 from CD99 Triggering in Ewing Sarcoma Delivers a Lethal Signal through p53 Pathway Reactivation and Cooperates with Doxorubicin
Authors: Guerzoni Clara , Fiori Valentina , Terracciano Mario , Manara Maria Cristina , Moricoli Diego , Pasello Michela , Sciandra Marika , Nicoletti Giordano , Gellini Mara , Dominici Sabrina , Chiodoni Claudia , Fornasari Pier Maria , Lollini Pier-Luigi , Colombo Mario P. , Picci Piero , Cianfriglia Maurizio , Magnani Mauro , Scotlandi Katia
Published: April 2023

Increased avidity and efficacy of dAbd over scFv C7 in 6647 EWS cell line.
Supplementary Tables from Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4–CHOP–DR5 Axis in Human Esophageal Cancer Cells
Authors: Chen Ping , Hu Tao , Liang Yupei , Li Pei , Chen Xiaoyu , Zhang Jingyang , Ma Yangcheng , Hao Qianyun , Wang Jinwu , Zhang Ping , Zhang Yanmei , Zhao Hu , Yang Shengli , Yu Jinha , Jeong Lak Shin , Qi Hui , Yang Meng , Hoffman Robert M. , Dong Ziming , Jia Lijun
Published: April 2023

Supplementary Table S1. Clinicopathologic parameters according to the expression of NAE1, UBA3 and UBC12. Supplementary Table S2. Clinicopathologic parameters according to the expression of global neddylation (global NEDD 8 conjugation).