bluuebunny/crossref_metadata_2025 huggingface dataset:
Educación por competencias en República Dominicana: perspectiva crítica sobre la práctica
Authors: Santana Soriano Edwin
Published: May 2020

Se intenta llamar la atención sobre algunas de las dificultades que se enfrentan a la hora de implementar el modelo de educación por competencias en el sistema educativo formal dominicano. Se hace un esbozo de las diferencias entre el denominado “modelo tradicional” y el modelo de educación por competencias para comparar la teoría con la práctica actual, presentar el enfrentamiento entre el deber ser y el ser en lo que atañe a la aplicación práctica del modelo en la República Dominicana, y poner en relieve algunas trabas para la instauración cabal del enfoque en lo que respecta a las exigencias que hace el modelo tanto al alumnado como al profesorado, frente a realidades y actitudes de ambos actores en el contexto dominicano, revelando limitaciones y vacíos que deben tenerse en cuenta para la adopción de políticas educativas que permitan su superación y lograr una ejecución fructífera del modelo.
Autoevaluación y acreditación universitaria en el contexto ecuatoriano. Perspectivas de análisis y mejora
Authors: Dillon Francisco , Rojas David , Robalino Jeanneth , Maldonado Mirian
Published: May 2020

La investigación, vinculación y docencia, también denominados condiciones institucionales, son primordiales al momento de analizar las fortalezas y debilidades de una institución de educación superior que pretende realizar procesos de autoevaluación y acreditación. Sin un adecuado análisis de esta información, estos procesos pueden derivar en análisis equivocados y planteamientos erróneos de acciones con fines prospectivos y de mejora continua. El objetivo de este estudio fue determinar la influencia de la articulación de estos procesos como un ejercicio de autoevaluación con fines de acreditación; para esto, se utilizó como marco metodológico y de análisis la teoría de redes. Como conclusión se menciona que los procesos sustantivos universitarios, principalmente la docencia, influyen y fortalecen de manera determinante la comunicación académica y la producción científica diferenciada por género en docentes universitarios con fines de autoevaluación-acreditación.
Una mirada al diseño instruccional y al desarrollo profesional de docentes de inglés como lengua extranjera
Authors: López Díaz Alexander
Published: May 2020

La enseñanza del Inglés como Lengua Extranjera (ILE) es un área de amplio crecimiento en República Dominicana. En este contexto, la figura del docente de ILE es preponderante. Este artículo tiene el objetivo de identificar dos aspectos clave en el campo profesional de la enseñanza: Diseño Instruccional (DI) y Desarrollo Profesional Docente (DPD). En primer lugar, se analiza la percepción de estos docentes concerniente a la secuencia o estructura del proceso de enseñanza-aprendizaje. En segundo lugar, se estudia qué consideran los maestros como DPD. Para recolectar datos relevantes, fue utilizada la encuesta como instrumento de investigación a través de un formulario de Google Forms (n=79). Los resultados de este estudio plantean una presencia predominante de enfoques tradicionales en la enseñanza del ILE que no refleja la corriente posmétodo actual, y una idea turbia con respecto a lo que realmente supone el desarrollo profesional docente, altamente limitada a programas de formación y promoción laboral. Al final del estudio, se discuten las implicaciones de estos resultados y recomendaciones para docentes en servicio.
Biofilm Formation and Extended Spectrum Beta Lactamase (ESBL) Production of Bacterial Strains Isolated From Sewage Water
Authors: Mercimek Takcı Hatice Aysun , Bakırhan Pemra , Genç Sema , Kaptanoğlu Melike
Published: May 2020

The
production extended spectrum beta lactamase (ESBL) and metallo-beta lactamase of strains grown biofilm that were isolated from
Kilis State Hospital sewage water were investigated in this study. Congo red
agar, tube adherence, tissue culture plate tests and SEM analysis were
performed for the detection of biofilm production. The extended spectrum beta lactamase and metallo-beta lactamase
expression of biofilm producing bacteria was tested by using Kirby-Bauer disc diffusion method according to CLSI
guidelines. 5 clinical isolates were revealed to be biofilm producer. From of
these isolates, Enterococcus spp. (C2)
and E. coli strains
showed strong biofilm producing. One of Enterococcus
isolates, SEM micrograph of C1 was viewed the weak adherence on glass surface. Only one from 5 isolates, Enterococcus spp. (C2)
strain was determined to synthesis ESBL enzyme. None of strains was observed to
not produce metallo-beta
lactamase. ESBL and biofilm production provide an important pathogenic
character allowing protection against antibiotic treatments to Enterococcus spp. (C2).
Pengaruh Desain Universal dan Usabilitas pada Fasilitas Publik di Perguruan Tinggi bagi Penyandang Disabilitas
Authors: Harahap Rachmita Maun
Published: May 2020

Interioritas bukan sekedar ilmu rancang ruang dalam yang memenuhi kebutuhan fungsi dan estetika semata. Kedua hal tersebut memang menjadi ‘tugas’ utama dalam desain interior. Setiap bangunan dirancang dan dibangun untuk memenuhi fungsi tertentu. Hotel, apartemen, dan rumah tinggal misalnya, berfungsi sebagai sarana akomodasi. Restaurant berfungsi sebagai bangunan komersial yang memenuhi kebutuhan pangan. Sebuah bangunan publik harus dapat diakses dan digunakan oleh berbagai kebutuhan yang berbeda. Bangunan-bangunan ini harus mampu diakses oleh mereka yang dapat melihat maupun tidak atau tuna netra, mereka yang mampu berjalan maupun pengguna kursi roda atau tuna daksa, serta mereka yang mampu mendengar maupun tidak atgau rungu. Paper ini merupakan sebuah kajian teoritis dan penerapan desain universal yang aksesibel  pada bangunan publik yang berfungsi sebagai universitas. Studi kasus yang diambil dalam penelitian ini adalah Universitas Mercu Buana di Jakarta Barat dan  Universitas Daedu di Daegu-Korea Selatan.  Penelitian dilakukan dengan mengaji desain universal pada kedua universitas tersebut dengan mempertimbangkan dua parameter, yaitu desain universal dan desain usabilitas, dengan melakukan studi literatur dan wawancara terhadap pengguna (user). Dari hasil penelitian didapatkan bahwa, universitas-, universitas di Daegu telah menjadikan faktor desain universal dan usabilitas sebagai bagian penting dalam desain, sedangkan kampus  Universitas Mercu Buana di Jakarta Barat belum sepenuhnya menjadikan kedua faktor tersebut sebagai bagian dalam desain, dengan banyaknya fasilitas yang tidak dapat diakses dan digunakan dengan baik secara universal.
An Integrative Review and Analysis of Cybersecurity Research: Current State and Future Directions
Authors: Walton Stephanie , Wheeler Patrick R. , Zhang Yiyang (Ian) , Zhao Xinlei (Ray)
Published: May 2020

Advances in information technology have greatly changed communications and business transactions between firms and their customers and suppliers. As a result, cybersecurity risk attracts ever increasing attention from firms, regulators, customers, shareholders, and academics. For instance, the Securities and Exchange Commission has released guidance on the disclosure of cybersecurity risks and incidents, along with potential internal control solutions, in the managers' discussion and analysis section of 10-K annual financial reports. Despite increasing interest in cybersecurity research, the literature lacks an integrative review of existing research identifying opportunities for future cybersecurity developments. In this study, we conduct an extensive analysis of cybersecurity-related papers in the accounting, information systems, computer science, and general business disciplines. Our review integrates and classifies 68 cybersecurity papers, examines cybersecurity determinants, consequences, and remedial strategies, and identifies future research opportunities based on the current state of the literature.
Design, Development and Evaluation of a New Hand Exoskeleton for Stroke Rehabilitation at Home
Authors: SERBEST Kasım , ELDOĞAN Osman
Published: May 2020

Rehabilitation at home is a growing need worldwide. Previous studies have suggested different devices in terms of motion and force transmission. In this study, we present design and development process of a novel hand exercise exoskeleton. The main advantages of our device that are portable, wearable, light weight (345 grams) and suitable for home use. The greatest feature of the device is the force transmitting mechanism. The spring mechanism manufactured by using commercial compression springs has some advantages in terms of size and weight. In design studies of the device, we have made use of the systematic approach. In this way, the best of three possible design solutions has been determined. Then the best design solution was selected. A few prototypes of the device were manufactured. The device has been tested clinically on both unimpaired individuals and hemiplegic hand patients for a short time. It was reported that the exoskeleton was suited to passive exercises. The result section gives an evaluation of the device in terms of exercises, ergonomics and the market. Additionally, a patent registration certificate was issued to our device for our country.
Effect of Bleaching Gel Concentration on Tooth Color and Sensitivity: A Systematic Review and Meta-analysis
Authors: Pontes MMA , Gomes JML , Lemos CAA , Leão RS , Moraes SLD , Vasconcelos BCE , Pellizzer EP
Published: May 2020

Objective:

The aim of this systematic review and meta-analysis was to evaluate a high concentration of hydrogen peroxide (35%) regarding tooth sensitivity and color change in tooth bleaching in comparison to low concentrations (6% to 20%).

Methods and Materials:

This review was conducted using the criteria of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and is registered on the Prospective Register of Systematic Reviews (CRD42017064493). The PICO question was “Does a concentration of hydrogen peroxide ≥35% using in-office bleaching procedure contribute to greater tooth sensitivity?” A search was made in PubMed/MEDLINE, Scopus, and the Cochrane Library.

Results:

Fourteen studies were selected for the qualitative analysis and seven for quantitative analysis. A total of 649 patients were evaluated (mean age: 36.32 years; range: 13.9 to 31 years), and the follow-up period ranged from one week to 12 months. The meta-analysis demonstrated that tooth sensitivity was higher in the patients submitted to treatment involving a high concentration of hydrogen peroxide (0.67; 95% confidence interval [CI]: 0.44 to 1.03; p=0.04; I2: 56%), and a significant difference was found regarding objective color ΔE (1.53; 95% CI: 2.99 to 0.08; p<0.0001; I2: 82%) but no significant difference was found regarding subjective color ΔSGU (0.24; CI: 0.75 to 1.23; p<0.00001; I2: 89%).

Conclusions:

This study indicated that a lower concentration of hydrogen peroxide causes less tooth sensitivity and better effectiveness in objective color change (ΔE); however, there is no difference between them related to subjective color (ΔSGU).
Análisis económico de productores y comercializadores de nopal en el Valle de Teotihuacán
Authors: Hernández Bonilla Blanca Estela , Ruiz Reynoso Adriana Mercedes , Ramírez Cortés Verónica , Sandoval Trujillo Sendy Janet , Dávila Hernández Margarita
Published: May 2020

Esta investigación se enfoca en el análisis de las condiciones económicas de la producción del nopal en la región en la que se ubica el Centro Universitario UAEM Valle de Teotihuacán. Fue desarrollada por un grupo multidisciplinario de investigadores de las áreas de economía, administración, contabilidad e informática, y comprende siete municipios del Estado de México: Acolman, Axapusco, Nopaltepec, Otumba, San Martín de las Pirámides, Temascalapa y Teotihuacán, donde la agricultura es una de las actividades más relevantes. En este estudio se estimaron las siguientes condiciones: situaciones laborales, proceso productivo, formas de comercialización, relación costo-beneficio y valoración de las hectáreas sembradas contra las cosechadas. Como parte de los resultados, en primera instancia, se pudo establecer que las condiciones laborales de la región son precarias. En ocasiones los productores prefieren dejar el producto en los plantíos a razón del bajo precio que ofrecen los compradores. Además, el nopal tunero está siendo sustituido por el nopal verdura, el cual brinda mayores posibilidades de rendimiento. Por otra parte, las plagas que afectan los plantíos influyen en el desinterés de los productores para implementar nuevas alternativas que generen mejores condiciones de producción, comercialización y utilidades. A través del presente estudio se determinó que se debe de difundir la importancia de estos productos típicos y altamente nutricionales con miras a su preservación. Adicionalmente, se identificó que en la región del Valle de Teotihuacán existen tres asociaciones de comercialización de nopal, tuna y xoconostle que agrupan a un número significativo de productores, las cuales han construido bodegas grandes con apoyo gubernamental con el objetivo de concentrar y comercializar el producto. El Centro Universitario UAEM Valle de Teotihuacán tiene el compromiso social de vincularse con los productores de la región para generar propuestas de solución a las diversas problemáticas identificadas y planteadas.
RANCANG BANGUN SISTEM PENGENDALIAN SUHU RUANG PENGERING HYBRID TIPE RAK BERPUTAR BERBASIS MIKROKONTROLER ARDUINO MEGA
Authors: Setiawati Diah Ajeng , Hakim Muhammad Lutfi , Sukmawaty Sukmawaty
Published: May 2020

Penelitian ini bertujuan untuk membuat sistem kontrol pengendalian suhu ruang pengering hybrid tipe rak berputar berbasis mikrokontroler Arduino Mega, dan melakukan uji kinerja terhadap sistem yang dirancang. Penelitian ini menggunakan metode eksperimental dengan percobaan di Laboratorium Daya dan Mesin Pertanian Fakultas Teknologi Pangan dan Agroindustri Universitas Mataram. Data yang dihasilkan kemudian dianalisa menggunakan aplikasi Mc. Excel. Hasil kalibrasi sensor suhu DS18B20 dengan termometer digital menunjukkan persamaan linieritas pada air hangat didapatkan  R2=0,999 dan air dingin R2=0,926. Hasil pengujian pada perlakuan tanpa bahan dan menggunakan bahan memperlihatkan sistem dapat bekerja dengan baik. Hal ini dilihat dari hasil pembacaan sensor suhu yang direspon oleh kondisi kipas pembuang panas dan penghembus panas. Nilai konsumsi daya listrik yang dibutuhkan oleh kipas sebesar 13,57 Watt dan untuk kebutuhan arus listrik sebesar 0,062 A.
PENGARUH LARUTAN PERENDAM SARI BELIMBING WULUH DAN GULA TERHADAP VASE LIFE BUNGA POTONG KRISAN STANDAR PUTIH (Dendranthema grandiflora L.) ‘WHITE FIJI’
Authors: Laksono Anang Dwi , Widyawati Nugraheni
Published: May 2020

ABSTRACT  Chrysanthemum cut flowers  (Dendranthema grandiflora L.) after harvest have a short vase life, so that efforts are needed to extend the freshness period. The basic principle of extending the freshness of cut flowers is through soaking in water containing sugar, controlling acidity, and microbes in the soaking solution. This research aims to determine the effect of wuluh starfruit extract and sugar concentrations in the soaking solution on the vase life of chrysanthemums. The research was conducted using Randomized Block Design (RBD) consisting two factors, that is concentration of wuluh starfruit (Averrhoa bilimbi Linn.) with variations concentration  0% (B0), 1% (B1), 2% (B2), 3% (B3) and white crystalline sugar with variations concentration 0% (S0), 1% (S1), 2% (S2), 4% (S3), so there are 16 treatment combinations. Each treatment was three repetitions. Data were analyzed using Analysis of Variants (ANOVA) followed by an Honestly Significant Difference Test (BNJ) with a 95% confidence levels. The results showed that treatment giving of wuluh starfruit extract 2% + 1% of sugar (B2S1) was able to maintain chrysanthemum cut flowers during storage with maintaining flower vase life up to 17.80 days. Keywords: Chrysanthemum, soaking solution, vase life
Pengendalian Suhu dan Kelembaban pada Budidaya Jamur Tiram Berbasis IoT
Authors: Fitriawan Helmy , Cahyo Kholid Ali Dwi , Purwiyanti Sri , Alam Syaiful
Published: May 2020

Oyster mushrooms (Pleurotus Ostreatus), such as white mushroom, chinese  mushroom, and warm mushroom, is one type of edible mushrooms. Oyster mushroom cultivation is usually done at the mushroom house (kumbung) which is mostly made of  bamboo.  Oyster mushrooms can grow optimally by controlling the temperature and humidity in the kumbung. Kumbung environment conditioning is usually done manually by spraying water on the planting medium every 8 hours.  But this is perceived as ineffective and requires high effort. For this reason, we need a technology that can monitor as well as control the environmental conditions inside the kumbung automatically and remotely. This paper describes the design of a system to monitor and control the temperature and humidity in the kumbung for oyster mushroom cultivation based on IoT (Internet of Things). This system is developed consisting of five parts, i.e sensor modules, microcontrollers, data loggers, actuators, and monitoring and control interfaces. The main result of this study is a remote monitoring and control of environmental conditions for oyster mushroom cultivation. The data of monitoring, in the form of temperature and humidity, are saved to the data logger and can be downloaded in the format (.csv). The system works functionally in accordance with the expected specifications, both in terms of sensor readings and actuator controlling.
NONTHERMAL PLASMA: A REVIEW ON ITS PROSPECTS ON FOOD PROCESSING
Authors: Arda Gede , Hsu Chuang Liang
Published: May 2020

Bringing plasma into food processing is a relatively new measure for food engineer and scientist. It is simple in generation, low energy requirement, high efficacy, and easy to apply, pave its way to be a new prospective scenario in processing more safety food recently. Plasma is the fourth matter after solid, liquid and gas contain various reactive species generated by electrical discharge from 10-120kV. Those are Reactive Oxygen and Nitrogen (RONS) comprising various reactive species including nitric oxide (NO), superoxide (O2-), hydrogen peroxide (H2O2); singlet oxygen (1O2); ozone (O3) and even hydroxyl radical (-OH) which can and do play important roles in biological systems. This brief review describes plasma interaction with the biological system and pesticides compound and sums up some finding on the nonthermal application on two main consideration of food safety namely microorganisms decontamination and pesticides residue degradation.
CITRA DAN HARAPAN TERHADAP KAWASAN KESAWAN DI KOTA MEDAN
Authors: Tampubolon Meta Vaniessa
Published: May 2020

Masyarakat yang tinggal di suatu kawasan akan mengalami kualitas fisik dan non fisik yang ada di kawasan tersebut secara langsung. Pengalaman sehari-hari dalam suatu kawasan akan menciptakan  citra dan harapan terhadap kawasan tersebut. Kawasan bersejarah dianggap penting sebagai karakter dan nilai citra suatu daerah. Kawasan Kesawan merupakan kawasan bersejarah yang berada di Kota Medan. Penelitian ini bertujuan untuk mengungkap citra dan harapan Kawasan Kesawan menurut penduduk Kota Medan. Penelitian ini menggunakan metode kualitatif yang bersifat eksploratif. Data dikumpulkan dengan membagikan kuesioner daring yang berisi pertanyaan terbuka. Kemudian didapatkan data teks yang berisi persepsi dan pemikiran masyarakat tentang citra dan harapan terhadap Kawasan Kesawan. Data tersebut dianalisis dengan analisis isi. Dari hasil analisis, terungkap bahwa citra Kawasan Kesawan yang dominan di mata penduduk Kota Medan adalah memiliki nilai sejarah tetapi tidak terawat. Terungkap pula bahwa mempertahankan bangunan lama dan tetap menjadikan Kawasan Kesawan sebagai kawasan bersejarah adalah harapan penduduk Kota Medan yang dominan.
TINJAUAN KRITIS: RESTORASI MINOR DAN MAYOR PADA HUNIAN TRADISIONAL CAGAR BUDAYA DI INDONESIA STUDI KASUS RUMAH TUO KAMPAI NAN PANJANG DAN RUMAH WAE REBO
Authors: Purwantiasning Ari Widyati
Published: May 2020

Tulisan ini merupakan sebuah tinjauan kritis tentang penerapan restorasi minor dan mayor pada hunian tradisional terutama yang ditetapkan menjadi cagar budaya di Indonesia. Studi kasus yang terpilih untuk diulas dalam tulisan ini adalah Rumah Tuo Kampai Nan Panjang yang terdapat di Sumatera Barat dan Rumah Wae Rebo yang terdapat di Flores. Tujuan dari penulisan ini adalah untuk dapat memahami lebih dalam tentang praktek kegiatan restorasi baik minor dan mayor terutama pada bangunan cagar budaya, dimana dalam hal ini difokuskan pada bangunan hunian tradisional. Metode yang digunakan dalam tinjauan kritis ini adalah kualitatif naratif deskriptif, dimana penulis memaparkan secara deskriptif kedua studi kasus dengan mengacu pada panduan Undang-Undang Cagar Budaya Indonesia No. 10 Tahun 2011 dan panduan prinsip-prinsip konservasi cagar budaya di Cina yang dianggap memiliki similaritas dalam penerapannya. Kata Kunci: restorasi minor, restorasi mayor, cagar budaya, Rumah Tuo Kampai Nan Panjang, Rumah Wae Rebo
PENDEKATAN KARAKTERISTIK RESPON GETARAN SISTEM 2 DOF SETELAH PENAMBAHAN INDEPENDENT DUAL TRANSLASIONAL DYNAMIC VIBRATION ABSORBER
Authors: Susastro Susastro
Published: May 2020

Dual Translational dynamic vibration absorber (dDVA) is two DVA masses that can move in the translational direction and given into the system to reduce system-translation translational vibrations. The research about using dual translational DVA to reduce vibration with the simulation method has been done, but a study about using the experimental method in that study to do validation from the simulation results that never been done. In this research we conducted a study related to the characteristics of 2 DOF system vibration response after the addition of dual translational DVA with an experimental approach and compared the results with simulation results data. Comparison between experiment date and simulation date is done in order to determine the level of error between the two methods. Simulation data is obtained by simulating the existing equations of motion from the study of literature, while the experimental data is obtained from testing with a DVA test with several changes in the frequency of excitation. From this research shows that the vibration characteristics of the experimental results are the same as the characteristics of the vibration of the simulation results, with an average significance level of 91.5%. The error that occurs between the results of the simulation and experiment is caused by the disappearance of some vibrations from the main system to the environment around the system, so that resulting differences result between simulation and experiment.
ANALISIS TERJADINYA SLIP PADA KOPLING DI UNIT SCANIA P 124 CB 8x4 NZ 420
Authors: Rasma Rasma , Purwono Hendro , Effendi Riki
Published: May 2020

In the operation of the unit whose successor does not use a hydraulic system, the role of the clutch is very important in transmitting power from the engine to the transmission. However, the clutch can only slip so that it can no longer function to forward power from the engine to the transmission. This can be caused by several things, including: wear on the clutch material, the presence of oil in the field of clutch surface, and spring damage to the clutch. On Scania P 124 CB 8x4 NZ 420 units this slip on clutch problem also occurs so research needs to be done to find the main cause. The method used in this study is to carry out checks and measurements and then the results are compared with the standard values that have been determined. The result shows that the cause of the slip on the clutch on the Scania P 124 CB 8x4 NZ 420 unit is 1) the presence of oil that wet the coupling surface is caused by a damaged seal shaft; 2) wear on clutch components namely clutch disc and pressure plate. To keep the seal shaft in good condition, regular and regular oil changes must be made and when the replacement of the seal shaft must be in accordance with the part number so that the possibility of the same problem can be reduced.
Academic and Social Expectations of Incoming College Students
Authors: Korstange Ryan , Brinthaupt Thomas , Martin Autumn
Published: May 2020

Students’ beliefs about themselves and their abilities shape their first-semester college experience. Previous studies have connected growth mindset and grit with increased graduation and retention relates, but mindset is likely to relate to other factors besides academic performance and re-enrollment. This article examines incoming students’ beliefs about their intelligence, social skills, work habits, and effort. Students (N = 332) also rated their likely reactions to a variety of hypothetical academic and social situations they might encounter during their first year of college. Our goal is to expand the conversation about the “college-ready” student mindset and develop a more accurate picture of the various beliefs students have when they enter college. The results demonstrate significant ethnicity, gender, and ACT score differences across the major measures, but not first-generational status differences. These results suggest that student support programming should take into consideration variations in student mindset.
Estimation of Accuracy of Determination of Parameters of the Buried Archaeological Objects According to the Data of Different-Altitude Magnetic Survey on the Basis of Numerical Modeling
Authors: Evmenov N. D. , Voronin V. V. , Dyadkov P. G. , Pozdnyakova O. A.
Published: May 2020

An algorithm for solving the inverse problem for determining the parameters of a buried archaeological object in the form of an elliptical cylinder (as a model of a typical burial or pit) is proposed. The estimation of accuracy of determination of parameters of the buried archaeological objects on the basis of the numerical solution of the inverse problem of magnetic prospecting for synthetic model is carried out. Its implementation included, firstly, the stage of modeling the magnetic field from a synthetic model of the archaeological site at three different heights for different parameters of the grid density and the size of the magnetic survey site and, secondly, the stage of solving the inverse problem from synthetic data at different heights, for different parameters of the magnetic survey and assessing the accuracy of the solution of the inverse problem. It is found that the accuracy of determining the parameters of the anomalous body is more affected by the size of the survey area than the density of the measurement network. There is also a tendency to increase the accuracy of determining parameters when using data of different heights. Approbation of the algorithm for solving the inverse problem on real data of different-altitude magnetic survey over the burial at the archaeological site Tartas-1 showed quite good results. The average error in determining the geometric parameters of the body and its occurrence is ~ 15 %.
Embedding Additional Natural Language Processing Tools into the TXM Platform
Authors: Soloviev F. N.
Published: May 2020

In our work we present a description of integration of natural language processing tools (pseudostem extraction, noun phrase extraction, verb government analysis) in order to extend analytic facilities of the TXM corpora analysis platform. The tools introduced in the paper are combined into a single software package providing TXM platform with an effective specialized corpora preparation tool for further analysis.
Virtual Atlas of Personified Human Anatomy “SkiaAtlas” and the Possibility of Its Application
Authors: Shcheglov B. O. , Bezulenko N. I. , Atashchikov S. A. , Scheglova S. N.
Published: May 2020

The work is devoted to the description of the structure of the developed SkiaAtlas software, which is focused on working with individual anatomical models of the human body and physiological parameters of the patient. The problem of using mock-up and post-sectional material in teaching medical students, and why the developed information system has advantages over these models, is shown. Virtual anatomical models were obtained from anonymous DICOM images of magnetic resonance imaging (MRI) and computed tomography (CT). The subsystems of the information system are described: a PACS server where all data is stored (server part) and a web application where the user works with data (client part). The information system modules implemented in the form of various software products are described in detail: data import module, anonymization module, DBMS module, visualization module, etc. The operation of these modules is illustrated schematically. It is shown in what programming languages and frameworks this software is implemented, and advantages of choosing these implementation tools relative to software are shown. The process of deleting personal data from DICOM files is described in detail; the process of obtaining the “mask” of the object in the picture, which is then used to obtain three-dimensional models of the patient’s internal organs. The process of user work with the database and the search for pathologies using the system interface tools are clearly described. The possibilities of using this information system in the educational field are shown – an illustration of specific clinical cases in order to search for cause-effect relationships in the pathogenesis of various diseases and the development of clinical thinking in a student. In a specific clinical case, an example is given of how the SkiaAtlas program was used to search for a pathology – a volumetric formation of the left hemisphere of the brain.
Chronological Complexes of the Iron and Middle Ages in the Trans-Urals (Based on the Materials of the Papskoe Settlement)
Authors: Matveeva Natalia P. , Zelenkov Alexander S. , Tretyakov Evgenii A. , Ovchinnikov Ivan Yu.
Published: May 2020

Purpose. In the article, we present materials from the new investigation of the multi–layered Papskoe settlement (hillfort) near the Iset River (Kurgan region). According to the results of the excavation, we identified six episodes of habitat in the Early Iron Age and in the Middle Ages.
Results. Stratigraphic layers of the shaft, traces from ground and frame-pillar structures, and burials, probably of the Chiyalik type, make it possible to establish types of local sequence. We identified individual ceramic complexes of Kushnarenkovo and Petrogromskoe types in addition to buildings with artifacts belonging to Medieval and Iron Age types. The results of our analysis of the typological features of ceramics in the chronological context of things and soil layers, as well as data of radiocarbon columns allow us to identify short scales of the activity of various groups in the valley of the Iset River.
Conclusion. In our opinion, the ancient population had used the site of the settlement repeatedly during the period from the 7th century BC to the 15th century AD in this sequence: the Baitovo – 7th–5th BC; the Sargatka – 4th–2nd BC; the Kashino – 2nd–1st BC; the Early Bakal – 4th–5th AD; the Late Bakal – 5th–7th AD; the Yudino – 9th–13th AD; the Chijalik – 14th–15th AD.
A Collection of Iron Arrowheads from the Museum “Rarity” in Bishkek
Authors: Khudyakov Yuliy S. , Borisenko Alisa Yu. , Soltobaev Orozbek A.
Published: May 2020

Purpose. The authors considered and analyzed various types of iron arrowheads that are kept as a part of weapon col-lection in the private museum “Rarity” in Bishkek, in the Kyrgyz Republic. We traced primary events related to the history of studying types of iron arrows that were detected at different times by scientists and modern collectors of antiquities on the territory of Tian Shan and Jetysu.
Results. The armament objects of long-range combat are classified according to their formal signs. All iron arrowheads from the collection studied were divided into particular groups and types by characteristic features of their section and form of feather. On the basis of our formal and typological analysis, we put forward several suggestions about possible functionality of the types of iron arrowheads that we singled out. Some arrowheads were intended for defeat of lightly-armed hostile warriors, whereas other types were created for archery against heavily-armed adversaries, who were defended by metal or chain armor. Still other arrowheads were universal and could be applied for shelling both warriors non-protected with metal armor and warriors who had those defensive means.
Conclusion. Our analysis of iron arrowheads from this collection can be used further for characterizing long-range combat weapon complexes of ancient and medieval warriors of several ethnic groups which resided on the territory of Tian Shan and Jetysu in the boundaries of the Kyrgyz Republic during the Hunnic times and following historical periods of the Early and High Middle Ages.
Intraocular tuberculosis, a challenge in diagnosis and treatment
Authors: Larroude Martina , Budmann Gustavo Ariel
Published: May 2020

Ocular tuberculosis (TB) is an extrapulmonary tuberculous condition and has variable manifestations. The incidence of TB is still high in developing countries, and a steady increase in new cases has been observed in industrial countries as a result of the growing number of immunodeficient patients and migration from developing countries. Choroidal granuloma is a rare and atypical location of TB. We present a case of a presumptive choroidal granuloma. This case exposes that diagnosis can be remarkably challenging when there is no history of pulmonary TB. The recognition of clinical signs of ocular TB is extremely important since it provides a clinical pathway toward tailored investigations and decision making for initiating anti-TB therapy and to ensure a close follow-up to detect the development of any complication.
Effect of Droplet Size and Counterions on the Spatial Distribution of Ions
Authors: Kwan Victor , Consta Styliani
Published: May 2020

Charged droplets have become a new environment for accelerating chemical reactions by orders of magnitude relative to their bulk analogues. Nevertheless the reaction mechanisms still remain unknown. Here we investigate the ion spatial distributions and surface charge in aqueous droplets with diameters in the range of 5 nm to 16 nm with and without counterions using molecular dynamics. The charge carriers are Na, and Cl ions ions. We demonstrate the convergence of ion spatial distributions. Scaling of the ion distributions reveals underlying universal behavior. The convergence allows one to extrapolate the simulation results from nanoscopic dimensions to larger ones, which are still inaccessible to atomistic modeling.The surface excess charge and electric field are also computed. We find that the surface excess charge layer in the presence of Na and Cl ions is approximately 1.5 nm-1.7 nm thick and that approximately 55%-33 % (from smaller to larger droplets) of the total number of ions reside in this layer. For the first time droplet sizes that are accessible to experimental scrutiny are modeled atomistically.
Influence of Packaging Material on Polyphenol Content and Antioxidant Activity in Some Commercial Beers
Authors: Bratu Mihaela Mirela , Birghila Semaghiul , Popescu Antoanela , Pirjol Bogdan Stefan Negreanu- , Radu Marius
Published: May 2020

Using two methods (ferric reducing antioxidant power and radical scavenging activity), the total polyphenol content (Folin–Ciocalteu reagent) and polyphenol patterns (HPLC) in 10 commercial lager beer brands produced in Romania was determined. Samples bottled in glass, plastic and aluminium packages were analysed for each brand when available. Results have indicated considerable variations in the total and individual phenolic contents as well as antioxidant activity across beer brands. A statistical analysis was performed to assess the influence of packaging type on the antioxidant activity and phenolic content of the beers. Statistical differences were found between the DPPH and FRAP methods in glass, aluminium and plastic material. Moreover, the antioxidant activity based on the DPPH method is influenced by the type of packaging material, while in the case of FRAP method, no statistical difference was reported. Furthermore, the same analysis has shown that the polyphenol concentration is invariant to the type of material.
Predicting the Shapes of Protein Complexes Through Collision Cross Section Measurements and Database Searches
Authors: Landreh Michael , Sahin Cagla , Gault Joseph , Sadeghi Samira , Lee Drum Chester , uzdavinys povilas , Drew David , Allison Timothy , Degiacomi Matteo , Marklund Erik
Published: May 2020

In structural biology, collision cross sections (CCS) from ion mobility mass spectrometry (IM-MS) measurements are routinely compared to computationally or experimentally derived protein structures. Here, we investigate whether CCS data can inform about the shape of a protein in the absence of specific reference structures. Analysis of the proteins in the CCS database shows that protein complexes with low apparent densities are structurally more diverse than those with a high apparent density. Using the CCS, molecular weight, and oligomeric states to mine the Protein Data Bank (PDB) for potentially similar protein structures, we find that we can distinguish oblate- and prolate-shaped protein complexes. We then apply the strategy to an integral membrane protein by comparing the shapes of a prokaryotic and an eukaryotic sodium/proton antiporter homologue. We conclude that mining the PDB with IM-MS data is a time-effective way to derive low-resolution structural models.
Ro5 Bioactivity Lab: Identification of Drug Candidates for COVID-19
Authors: Yang Zeyu , Bastas Orestis , Demtchenko Mikhail , Pabrinkis Aurimas , Jamieson Cooper Stergis , Bačkis Danius , Knuff Charles Dazler , Jočys Žygimantas , Tal Roy
Published: May 2020

The public health emergency known as the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a large number of deaths worldwide and major socioeconomic disruption. To date, no broadly effective antiviral treatment or vaccine has been developed for COVID-19. In response to this dire situation, Ro5 deployed its AI Lab to accelerate the search for potential treatments. This report focuses on our use of the Ro5 Bioactivity model, which has been designed to predict the inhibitory activity of small molecules against protein targets. The model screened a vast range of compounds in silico to uncover potential inhibitors of the SARS-CoV-2 3CL protease. We hereby present the most propitious candidates from this screen. The highest-ranking molecules include Nelfinavir, Saquinavir, Itacitinib, Kynostatin-272, BOG-INS-6c2-1, and BEN-VAN-d2b-11. Subsequent docking simulations corroborate their plausibility as 3CLpro inhibitors. Nelfinavir and Itacitinib hold the most promise for drug repurposing, among all the molecules proposed herein, due to their high predicted inhibition and affinity against the 3CL protease, favourable pharmacokinetics, and encouraging experimental data for treating viral replication and hyperinflammation, respectively.
Tyrosine-Selective Bioconjugation with Iminoxyl Radicals
Authors: Maruyama Katsuya , Ishiyama Takashi , Seki Yohei , Oisaki Kounosuke , Kanai Motomu
Published: May 2020

A novel Tyr-selective protein bioconjugation using the water-soluble persistent iminoxyl radical is described. The conjugation proceeded with high Tyr-selectivity and short reaction time under biocompatible conditions (room temperature in buffered media under air). The stability of the conjugates was tunable depending on the steric hindrance of iminoxyl. The presence of sodium ascorbate and/or light irradiation promoted traceless deconjugation, restoring the native Tyr structure. The method is applied to the synthesis of a protein-dye conjugate and further derivatization to azobenzene-modified peptides.
GlycoTorch Vina: Improved Docking of Sulfated Sugars Using QM-derived Scoring Functions
Authors: Boittier Eric , Burns Jed , Gandhi Neha , Ferro Vito
Published: May 2020

Glycosaminoglycans (GAGs) are a family of anionic carbohydrates that play an essential role in the physiology and pathology of all eukaryotic life. Experimental determination of GAG-protein complexes remains difficult due to the considerable diversity in both carbohydrate linkage, and sulfation patterns. To complement existing methods of structural determination, we present our molecular docking tool, GlycoTorchVina (GTV), which demonstrates a substantial improvement at reproducing low energy conformations of GAGs compared with traditional docking programs. Based on the carbohydrate specific docking program VinaCarb (VC), GTV utilizes rotational energy functions, calculated using density functional theory (DFT), specifically designed for glycosidic linkages found in GAGs. The redocking accuracy of four programs (GTV, VC, AutoDock Vina and Glide) was tested over a set of 10 high-quality crystal structures containing co-crystallized GAGs (tetrasaccharides or longer). GTV outperformed other programs and was able to reproduce the native pose of eight structures and produced top-scoring docked poses that were on average only 1.8 Å RMSD away from the crystal structure. Although imitation of crystal structures is a standard test used for assessing the accuracy of docking programs, we illustrate how the underlying quality of the crystal structure, which is often overlooked during benchmarking, affects conclusions drawn from this approach. Statistical and theoretical investigations into charge-charge (“salt-bridge”) interactions are also presented. Again, DFT calculations were used to derive non-bonded potentials describing salt-bridges, and solvent-mediated charge-charge (“water-bridge”) interactions. These data suggest that water-bridges play an important, yet poorly understood, role in the structures of GAG-protein complexes.
Making Hydrogels Stronger through Hydrophilicity-Hydrophobicity Transformation, Thermoresponsive Morphomechanics and Crack Multifurcation
Authors: HU YUBING , Barbier Lucile , Li Zhao , Ji Xiaofan , Blay Heiva Le , Liu Junkai , Lam Jacky W. Y. , Marcellan Alba , Tang Ben Zhong
Published: May 2020

The development of mechanically strong, flexible and crack-resistant hydrogels is of great academic and practical significance and demands for the biomimetic exploration of energy dissipation pathways. The rational design of strong hydrogels is also limited by insufficient mechanism study, resulting from the lack of powerful technique to “see” hydrogels at morphological level. Herein, we constructed a thermoresponsive mechanically strong hydrogel from poly(N-isopropylacrylamide) (PNIPAM) and poly(N,N-dimethylacrylamide). Its hydrophilicity-hydrophobicity transformation and composition-dependent microphase separation are directly visualized by using luminogens with aggregation-induced emission as fluorescent indicators. Based on the morphological observation and mechanical measurements, the concept of morphomechanics with a comprehensive mechanism clarification is proposed. In this regard, thermoresponsive strengthened mechanical properties are attributed to the entanglement of PNIPAM chains and the formation of multiple noncovalent interactions, mainly hydrogen bonds. The enhanced fracture energy by crack multifurcation is related to the disruption of weak interfaces between two separated phases.
Fighting And Chasing The Rogue Virus-Covid19
Authors: Pooja Shah  , Waqar Naqvi
Published: May 2020

The novel coronavirus of 2019, COVID-19, also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread from its origin Wuhan, China to the rest of the world.It is important to note that while the number of new cases has reduced in China lately, they have increased exponentially in other countries including South Korea, Italy and Iran. In India, the COVID-19 trajectory appears assured to change modes. While the number of incidents grew slowly in February, they doubled in just five days in mid-March from 100 to more than 236, and now at the end of April, the cases reported are 29,435.These numbers are possibly an underestimate of the infected and dead due to limitations of surveillance and testing. . The Indian government declared a countrywide shutdown for a period of 3 weeks from 24th of March to help prevent the spread of the virus. Most of the affected people had connection with flyers from covid-19 affected countries; some of them had no such interaction, indicating that community transmission could have started in several parts of India. Thus an important collective goal is to reduce the outbreak and to flatten the peak of the outbreak curve. Cooperation is a crucial tool in the COVID-19 battle. There is a need to identify and find a way around the particular threats, the overarching cultural and social patterns in our area. This article discusses the tactics thatshould build for handling the crisis.
¿Qué Factores, Internos y Externos, Determinan el Nivel de Ereadiness? Análisis de las PYMES Españolas
Authors: Estébanez Raquel Pérez , Ríos-Manríquez* Martha , Colomina Clara Isabel Muñoz , Espada Manuela Cañizares
Published: May 2020

Objetivo del estudio: Los objetivos son realizar un modelo holístico y teóricamente construido que identifique los factores contextuales y organizativos que pudieran afectar al nivel de eReadiness, y determinar qué factores internos y externos a la organización influyen en el nivel de eReadiness de las empresas.Metodología/enfoque: Con una muestra de 88 Pymes, se realizó un estudio cuantitativo, mediante un análisis multivariante de regresión lineal por pasos atrás.Originalidad/Relevancia: Esta investigación analiza el nivel de eReadiness, para comprobar qué factores, internos y externos, influyen en las Pymes en un país desarrollado, en un sentido amplio y no sólo respecto al comercio electrónico.Principales resultados: Los resultados muestran que las PYMES consideran que el reconocimiento de las oportunidades y amenazas de las TIC afecta a su nivel de eRediress y que las estrategias diseñadas por la administración necesitan el apoyo de diferentes instituciones gubernamentales.Contribuciones teóricas/metodológicas: Esta investigación aporta un mejor entendimiento del nivel de  eReadiness de las Pymes, indicando los factores, internos y externos, motivan su desarrollo y cuales frenan su crecimiento.Aportes sociales/de gestión: Esta investigación refleja una mejora en la comprensión del grado de eReadiness en las Pymes españolas, lo cual implica que las empresas han establecido estrategias y modelos opcionales con una visión clara de los proyectos en tecnológicos, con implicaciones para la sociedad, pues una mejor eReadiness implica mejor atención a las necesidades de la sociedad.Palabras clave: eReadiness, factores internos, factores externos, Pymes, país desarrollado
Relational practice in the workplace: women's talk or gendered discourse?
Authors: Holmes Janet , Marra Meredith
Published: May 2020

No description supplied
A pattern of alcohol consumption among marijuana users in the adult population of the city of Gdańsk
Authors: Brosz Maciej
Published: May 2020

Alcohol and marijuana are the most commonly used psychoactive substances both in Europe and Poland. In the last four years the proportion of marijuana users in the adult population of Gdańsk has almost doubled: from 7.1% in 2015 to 14.1% in 2019. The surveys concerning the consumption of alcohol conducted every four years since 2007 indicate a significant fact: the proportion of people who drink is decreasing. However, this does not mean that they drink less or less often. A question elaborated in this article is whether marijuana users consume more or less alcohol than non-users. This article is based on the data collected in a questionnaire survey on alcohol and other psychoactive substance use conducted in Gdańsk in the autumn of 2019 on a representative sample of 1,004 adult residents of the city.