bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of vitamin D and leptin levels in PCOS in young women: A family medicine perspective
Authors: Siddiqui Merajul Haque , Beg Aisha , Dixit Ritvija , Verma Shailza , Gunjan Gagan , Agrawal Sonu Kumari
Published: June 2024

ABSTRACT

Introduction:

Adolescent girls and young women of childbearing age are the main populations affected by endocrinopathy known as polycystic ovarian syndrome (PCOS). It is especially important to take into account whether clinical and biochemical signs of hyperandrogenism are present in female patients. In maintaining metabolic homeostasis, leptin is crucial. According to research, vitamin D deficiency may play a role in the pathophysiology of PCOS by contributing to insulin resistance, inflammation, dyslipidaemia, and obesity, which are all conditions linked to the syndrome. In this study, leptin and vitamin D3 levels will be measured in order to determine how each relates to the aetiology of PCOS.

Materials and Methods:

Hundred young women were allocated into two groups, 50 women with PCOS (diagnosed on the basis of revised Rotterdam criteria for PCOS), taken as a study group, and 50 healthy women with no PCOS as control group. Blood samples were collected and tested for hormonal parameters.

Results:

Between the two groups, there were no appreciable variations in demographic traits. Study groups were found to have considerably higher serum leptin levels than control groups. The study group’s vitamin D3 levels were found to be lower than those of the control group.

Conclusion:

Patients with PCOS are a special population with distinctive hormonal profiles that differ from typical profiles in healthy populations. Comparing PCOS to healthy individuals, leptin levels were higher while vitamin D3 levels were lower. It is necessary to conduct more extensive research on the involvement of leptin and vitamin D3 in the aetiology of PCOS.
Lymphocyte as a predictor of prognosis of COVID-19 patients: A hospital-based study
Authors: Biakhlupuii C. , Vanlalpeka Johan , Lalrinpuia Benjamin , Laltlanzovi  , Devi Ksh G. , Hrahsel Lalrinawmi
Published: June 2024

ABSTRACT

Introduction:

Lymphocytopenia has emerged as a simply obtained laboratory value that may correlate with prognosis. In this study we aim to study absolute Lymphocyte count after clinical recovery.

Method and material:

Observational study was conducted in Covid dedicated Hospital in Mizoram. Absolute lymphocyte count is obtained from the differential leucocyte count of the patients. The obsolute Lymphocyte count at the time of hospital admission is compared with the Absolute Lymphocyte count at the time of hospital discharge after the patient obtained clinical recovery.

Result:

Absolute Lymphocyte Count at the time of admission has a mean of 2004.48 and standard deviation of 1204.868. Absolute Lymphocyte Count at the time of discharge has a mean of 1943.68 and standard devaiton of 842.228. Pearsons correlation coefficientis showed that there is positive correlation between the variables (Correlation coeffiecient = .325). Also, the correlation is statistically significant (P < 0.05). Paired Sample t-test showed there is no statistical significant difference between Absolute Lymphocyte Count- at the time of admission and at the time of discharge (P > 0.05) at 95% Conficence Interval.

Conclusion:

Our study showed that Absolute Lymphocyte count had no signicant difference at the time of hospital admission and after clinical recovery.
A cross-sectional study on diabetes self-management practice and its association with glycemic control among type 2 Diabetes patients
Authors: Kumar Deepak , Burma Amrita , Peter Sherley , Ansari Mohd A. , Patankar Anand
Published: June 2024

ABSTRACT

Context:

Diabetes has emerged as a major chronic public health problem throughout the world. Self-management by diabetes patients is very important for controlling blood sugar levels and preventing complications of diabetes.

Aims:

The present study was conducted to study self-management practices among diabetes patients and to analyse socio-demographic factors associated with them.

Methods and Materials:

A cross-sectional analytical study was conducted among 230 randomly selected diabetes patients in the Andaman and Nicobar Islands. The self-management practices were measured by the diabetes self-management questionnaire (DSMQ).

Statistical Analysis Used:

The association of the DSMQ score with socio-demographic factors and blood sugar level was analysed by statistical tests like the T-test, analysis of variance (ANOVA) test, Tukey’s honestly significant difference, and Chi-square test.

Results:

The mean DSMQ score of the diabetes patients was 29.55 ± 5.98. There was a significant difference between the mean DSMQ score and the educational level (P value = 0.009), residential status (P value = 0.037), and duration of diabetes (P value = 0.006). The subcomponent analysis of the DSMQ score revealed that the glucose management score of rural people (9.38 ± 3.36) was significantly higher (P value = 0.006) than that of urban people (8.32 ± 2.46), and the diet control score was significantly higher (P value = 0.02) in patients with normal post-prandial blood sugar (PPBS) (7.64 ± 2.18) than in patients with raised PPBS (6.96 ± 2.12).

Conclusions:

Higher educational level, rural background, and long duration of diabetes were associated with better self-management practices. The patients with normal blood sugar levels showed higher diet control scores than the patients with raised blood sugar levels.
Adiponectin and TNFα in relation to glucometabolic control in patients with type 2 diabetes mellitus
Authors: Habib Syed Shahid , Al-khlaiwi Thamir , Al-khliwi Huthayfah , Habib Syed Mohammad , Habib Syed Abubakar , Habib Syed Hamid , Khan Adeena
Published: June 2024

ABSTRACT

Background:

The correlation of adiponectin and serum tumor necrosis factor alpha (TNFα) with glucometabolic parameters in diabetes mellitus (DM) needs further studies. We aimed in this study to evaluate the relationship between adiponectin and TNFα with glucometabolic parameters in patients with type 2 DM (T2DM).

Methods:

We conducted a cross-sectional study in the Department of Physiology, College of Medicine, King Saud University, Saudi Arabia. The sample size was 117 from the diabetes clinic of King Abdul-Aziz University hospital through the convenience sampling technique. Subjects were grouped into control (healthy) subjects (53) with no chronic diseases and the diabetic group (64) with confirmed T2DM. Socio-demographic data were collected along with the serum blood sample to analyze the variables.

Results:

Adiponectin was significantly high in healthy subjects compared to the diabetic group (control: 14.4 ± 4.3, T2DM: 11.0 ± 4.1, P = 0.000), while TNFα was higher in the T2DM group (7.8 ± 2.7) than in the control group (6.6 ± 2.9, P = 0.024). TNFα was negatively correlated with adiponectin in the control group (-0.279) and in diabetic subjects (-0.311) and positively correlated with HbA1c in the diabetic group (0.319) and triglycerides (0.252). Adiponectin was positively correlated with HDL in the control group (0.252) and in diabetic subjects (0.326). There was an inverse correlation between TNFα and adiponectin.

Conclusion:

Adiponectin is higher in healthy subjects than in diabetic patients, while TNFα is higher in diabetic patients. In addition, adiponectin is positively correlated with HDL in healthy as well as diabetic patients. TNFα is positively correlated with HbA1c and triglycerides.
Association of serum ferritin trends with liver enzyme patterns in β-thalassemia major: A longitudinal correlational study
Authors: Rabadiya Samarth Mukesh , Yogesh M , Nagda Jay , Gandhi Rohankumar , Makwana Naresh
Published: June 2024

ABSTRACT

Background:

β-Thalassemia major patients require lifelong blood transfusions, leading to iron overload and liver injury. This study examines the longitudinal association between serum ferritin and liver function over 5 years in pediatric patients.

Methods:

This retrospective study included 582 transfusion-dependent thalassemia patients aged 1–18 years. Serum ferritin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and albumin were measured annually. Correlation and linear regression analyses assessed associations between ferritin trajectories and liver enzymes.

Results:

Mean ferritin rose from 1820 ± 960 ng/mL at baseline to 4500 ± 1900 ng/mL at year 5, indicating worsening iron overload. AST and ALT levels also steadily climbed over follow-up, whereas albumin declined slightly. Ferritin correlated positively with AST (r = 0.675, P < 0.01) and ALT (r = 0.607, P < 0.01), but not with albumin (r = -0.143, P = 0.153) annually. The regression interaction term showed within-patient ferritin increases over time were independently associated with escalating AST and ALT (P < 0.05), after adjusting for confounders.

Conclusion:

Rising ferritin levels predict progressive liver injury in regularly transfused pediatric thalassemia patients. Tighter control of iron overload may help preserve hepatic function.
A rare manifestation of serum sickness after common krait envenomation in a patient treated with polyvalent anti-snake venom in India: Presentation and challenges
Authors: Guru Satyabrata , Bellapukonda Snigda , Mohanty Chitta R. , Radhakrishnan Rakesh V. , Gupta Anju
Published: June 2024

ABSTRACT

Envenomation from snakebites is a significant public health concern in the Southeast Asian region resulting in considerable mortality and morbidity. Anti-snake venom (ASV) despite being the only rescue can bring forth several acute and delayed adverse effects. Among them, serum sickness is a late manifestation after treatment with ASV that presents after 5–14 days of treatment. However, there is no specific definition to diagnose serum sickness or proven treatment. Here, we present a case of serum sickness to provide an insight into this unventured zone, briefing the presentation, treatment and probable reason for serum sickness and its prevention after common krait envenomation and treatment with polyvalent ASV in India.
HRV changes in young adults with depression
Authors: Kumar Chandan , Sakshi Pooja , Sinha Niska , Sunita  , Kumar Tarun
Published: June 2024

ABSTRACT

Background and Aims:

Depression is a common and debilitant mental health disorder that is very common among young adults of the age group of 18-25 years. There is evidence that autonomic nervous system dysfunction associated with depression may play an important role in cardiovascular disease among patients with depression. HRV that is used to assess ANS function is found to be altered in depression. Since the HRV findings associated with depression remain inconsistent, this study is aimed to find HRV changes associated with depression so that the use of HRV as a diagnostic tool for depression can be validated.

Methods:

A total of 42 newly diagnosed patients of depression of the age group (18-26) years and 89 non-depressed volunteers matched for age, BMI and sex proportions were included in the study. Heart rate variability was recorded using five-minute stationary RR interval of Lead II by 4-channel Power Lab System (AD Instrument Ltd). HRV findings are summarized into Time-Domain parameters, Frequency-Domain parameters and Non-Linear parameters.

Result:

All HRV parameters are significantly reduced and the LF/HF ratio is significantly raised (P < 0.05) in the group of depressive patients when compared to the group of healthy controls. The reduction of HRV parameters (SDRR, RMSSD, Total Power, SD1 and SD2) in the group of patients with depression is found to be highly significant (P < 0.0001).

Conclusion:

The findings of our study suggest that depression may be associated with alterations in ANS activities, which contribute to an increased risk of cardiovascular disease. Thus, HRV can serve as a potential bio-marker for depression.
Milk Adulterants: Serious Impact on Human Health
Authors: Choudhary Madhu , Sharma Nitin
Published: June 2024

Milk has been an indispensable part of our diet because of its rich content of vital nutrients. The demand and supply gap in milk production along with its perishable nature have resulted in the increased menace of milk adulteration. Various adulterants such as detergents, urea, ammonium salts, sodium chloride, nitrates, sulphates, salicylic acid, benzoic acid, hydrogen peroxide, formaldehyde, boric acid, neutralisers and melamine present in the milk give rise to serious health problems such as nausea, gastroenteritis, hepatitis, renal failure, heart problems, asthma, pneumonia, cancer and allergic reactions. This paper describes the adverse health effects of consuming adulterated milk.
Navigating Sample Size Estimation for Qualitative Research
Authors: Sharma Suresh K. , Mudgal Shiv Kumar , Gaur Rakhi , Chaturvedi Jitender , Rulaniya Satyaveer , Sharma Priya
Published: June 2024

There are well-established rules and methods about sample size estimation in quantitative research approaches. However, qualitative research approaches justify very little about sample size estimation principles and largely depend on subjective judgements and arbitrariness. Contrarily, an adequate sample size is essential for a study to address the core elements of validity and credibility in qualitative research too such as rigor, trustworthiness, conformability and acceptance. Therefore, this review was carried out to explain the available methods to estimate sample size for qualitative studies. After conducting a thorough literature review, we discovered related articles that explore the estimation of sample size for qualitative studies. By examining these findings and integrating the information with our personal experience for estimation of sample size in the field of qualitative studies, we have produced an all-encompassing narrative review. After an in-depth literature search, four different approaches were described in this paper to answer the question of how to estimate sample size in qualitative studies. The four approaches described in this paper are (a) rules of thumb, (b) conceptual models, (c) concept of saturation and (d) statistics-based methods for sample size estimation in qualitative research. The paper presents four methods for estimating sample size in qualitative studies and simplifies the statistical approach for saturation calculation in qualitative studies. Yet, it is vital to responsibly integrate these methods, acknowledging their limitations and maintaining the importance of sample size estimation in qualitative studies.
J1939 Digital Annex
Authors:   Truck Bus Control and Communications Network Committee
Published: June 2024

This document is intended to supplement the SAE J1939 documents by offering the SAE J1939 information in a form that can be sorted and search for easier use.
Imaging features and management of focal liver lesions
Authors: Kahraman Gökhan , Haberal Kemal Murat , Dilek Osman Nuri
Published: June 2024

Notably, the number of incidentally detected focal liver lesions (FLLs) has increased dramatically in recent years due to the increased use of radiological imaging. The diagnosis of FLLs can be made through a well-documented medical history, physical examination, laboratory tests, and appropriate imaging methods. Although benign FLLs are more common than malignant ones in adults, even in patients with primary malignancy, accurate diagnosis of incidental FLLs is of utmost clinical significance. In clinical practice, FLLs are frequently evaluated non-invasively using ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). Although US is a cost-effective and widely used imaging method, its diagnostic specificity and sensitivity for FLL characterization are limited. FLLs are primarily characterized by obtaining enhancement patterns through dynamic contrast-enhanced CT and MRI. MRI is a problem-solving method with high specificity and sensitivity, commonly used for the evaluation of FLLs that cannot be characterized by US or CT. Recent technical advancements in MRI, along with the use of hepatobiliary-specific MRI contrast agents, have significantly improved the success of FLL characterization and reduced unnecessary biopsies. The American College of Radiology (ACR) appropriateness criteria are evidence-based recommendations intended to assist clinicians in selecting the optimal imaging or treatment option for their patients. ACR Appropriateness Criteria Liver Lesion-Initial Characterization guideline provides recommendations for the imaging methods that should be used for the characterization of incidentally detected FLLs in various clinical scenarios. The American College of Gastroenterology (ACG) Clinical Guideline offers evidence-based recommendations for both the diagnosis and management of FLL. American Association for the Study of Liver Diseases (AASLD) Practice Guidance provides an approach to the diagnosis and management of patients with hepatocellular carcinoma. In this article, FLLs are reviewed with a comprehensive analysis of ACR Appropriateness Criteria, ACG Clinical Guideline, AASLD Practice Guidance, and current medical literature from peer-reviewed journals. The article includes a discussion of imaging methods used for the assessment of FLL, current recommended imaging techniques, innovations in liver imaging, contrast agents, imaging features of common nonmetastatic benign and malignant FLL, as well as current management recommendations.
Tasavvuf Tarihi Araştırmalarında Bir Fotoğraf Okuma Örneği: “Gümüşhanevî Fotoğrafları” Üzerine Nitel Görüntü Analizi
Authors: Dinçer Celalettin
Published: June 2024

XIX. yüzyılın önde gelen Halidî şeyhlerinden Ahmed Ziyaüddin Gümüşhanevî (v.1894), dönemin dinî ilimler, tasavvuf ve siyasî hayatında çok önemli bir yere sahiptir. Son yıllarda, Gümüşhanevî’ye ait olduğu iddia edilen fotoğraflar, değişik mecralarda sıkça karşımıza çıkmaktadır. Bu çalışmanın amacı, söz konusu fotoğrafların gerçekten Gümüşhanevî’ye ait olup olmadığı sorusuna cevap aramaktır. Araştırmamızda temel olarak “Fotoğraf Okuma Yöntemi” kullanılacaktır. Görsel kaynakların değerlendirilmesinde kullanımı giderek artan bu yöntem, ilk kez bir tasavvuf tarihi araştırmasında kullanılacaktır. Çalışmamızda geliştirdiğimiz yaklaşımın, benzer sorunların çözümüne de yardımcı olacağı, alan araştırmalarına katkı sağlayacağı değerlendirilmektedir.
Kepemimpinan Rohani John O. Sanders Dalam Peningkatan Kepemimpinan Gereja Yang Melayani Tanpa Diskriminasi
Authors: Tanasyah Yusak , Repi Robby Robert , Dumgair Bartholomeus Marthin , Limahelu Jackqualine , Tahya Leanard , Agung Robert
Published: June 2024

Effective spiritual leadership, which has been practiced by many church leaders around the world, is related to motivation, individual potential development, and building a solid team. But that alone is not enough; the ability to manage crises, change and carry outgrowth, are the dominant demands in leadership. Leadership skills require not only skills but also require inspiration, wisdom, and commitment. Everyone today crave leadership, need leadership figures who can be relied on, trusted, and can actualize constructive changes. We need leadership capable of transforming the character of the church, providing strategic changes, as well as being able to increase the potential of the individuals it leads, effectively managing resources and having the desire to be actively involved in the process against discrimination. J Oswald provides the basis for good spiritual leadership in church leadership so that it can bring servant leadership and fight discrimination.
 
Kepemimpinan rohani yang efektif yang selama ini telah dilakukan banyak pemimpin gereja di seluruh dunia, adalah yang berkaitan dengan motivasi, pengembangan potensi individu, dan pembentukan team yang solid. Namun itu saja tidak cukup; kemampuan mengelola krisis, perubahan dan melakukan pertumbuhan-pertumbuhan, menjadi tuntutan dominan dalam kepemimpinan. Keahlian kepemimpinan membutuhkan tidak saja ketrampilan namun juga membutuhkan inspirasi, kearifan dan komitmen. Semua orang saat ini mengidamkan kepemimpinan, membutuhkan figur kepemimpinan yang dapat diandalkan, dipercaya dan dapat mengaktualisasikan perubahan-perubahan konstruktif. Kita membutuhkan kepemimpinan yang mampu mentransformasikan karakter gereja, memberikan perubahan-perubahan strategis, sekaligus yang dapat meningkatkan potensi individu-individu yang dipimpinnya, efektif mengelola sumber daya dan memiliki keinginan untuk aktif terlibat dalam proses melawan diskriminasi masih terjadi dalam banyak bagian. J. Oswald memberikan dasar kepemimpinan rohani yang baik dalam kepemimpinan gereja sehingga dapat membawa kepemimpinan yang melayani serta melawan diskriminasi.
THE MEANING OF LIFE
Authors: Andrian Hengky , Sutrisno Sutrisno , Budiyanto Henoch
Published: June 2024

This research seeks to find an accurate explanation of the meaning of life that is widely discussed by the 'world' with its various philosophies. Of course, there will be encounters and separations when the philosophical study of the meaning of life in general is re-examined by the study of Christian theology - which in this context the researcher uses a biblical review. The Bible is a book of mystery; revealing with 'secret' sentences like an abstract painting. Yet it contains many philosophical expressions that are no less profound, accurate, and relevant than the philosophical views of the 'world'. In this way, Christian excellence will appear to 'shine' among the various human inventions in the search for the meaning of life. Through a rigorous comparative approach, the study aims to identify common themes, points of divergence, and underlying philosophical assumptions that underpin these diverse views on life's meaning. It delves into concepts such as purpose, morality, suffering, and transcendence, seeking to uncover the underlying principles that guide individuals and communities in their pursuit of a meaningful existence. By critically evaluating these non-Christian and Christian perspectives, the research contributes to a deeper understanding of the complexities surrounding the question of life's meaning. It provides readers with a nuanced appreciation of the various intellectual and spiritual traditions that shape our understanding of human existence, ultimately inviting reflection and dialogue on this timeless and profound topic.
METABÓLITOS SECUNDÁRIOS E COR DE FOLHAS DE Bauhinia forficata Link e Piper aduncum L. SUBMETIDAS À SECAGEM EM LEITO FIXO E FLUIDIZADO
Authors: Siqueira Valdiney Cambuy , Fróes Air Lisbôa , Da Silva Denise Brentan , Mabasso Geraldo Acácio , Zanuncio Vanessa Samudio Santos , Quequeto Wellytton Darci , De Castro Larissa Kathleen
Published: June 2024

Grande parte dos compostos oriundos das plantas medicinais são sensíveis aos processos de secagem. Dessa forma, é importante a adequação das condições de secagem, como temperatura e velocidade do ar, visando um processo eficiente, e que não influencie negativamente a qualidade do produto. Assim, objetivou-se avaliar o efeito de diferentes sistemas de secagem sobre a cor e os compostos das folhas de B. forficata e P. aduncum. Realizou-se a secagem nas temperaturas de 40, 50 e 60°C em leito fixo e fluidizado. Avaliou-se a cor das folhas frescas e secas, posteriormente feita a extração dos compostos, com etanol. O estudo foi conduzido seguindo um delineamento inteiramente casualizado em esquema fatorial 3 × 2 e quatro repetições. Conclui-se que a condição de 60°C em ambos os sistemas de secagem e 40°C em leito fluidizado resultou em maiores concentrações dos compostos oriundos das folhas de B. forficata. Enquanto para os extratos de P. aduncum, as maiores concentrações dos compostos foram na temperatura de 60°C em ambos os sistemas de secagem, e 50°C em leito fixo. Após a secagem, as folhas de B. forficata ficaram mais esverdeadas, amarelas, e claras, e apresentaram cores mais intensas, porém com menor tonalidade. Já as folhas de P. aduncum ficaram mais avermelhadas, azuis e escuras, expondo cores menos intensas, porém com maior tonalidade.
ESTÁGIO EM EDUCAÇÃO ESPECIAL NA PEDAGOGIA
Authors: Barros de Borba Bruna , Haas Clarissa , Costa da Silva Mayara , Rodrigues de Freitas Claudia
Published: June 2024

Analisamos a realização do estágio docência na área da educação especial como um percurso da formação inicial em Pedagogia em uma universidade pública do país, buscando compreender os efeitos formativos dessa ação para a docência nos processos escolares inclusivos. A abordagem da pesquisa é qualitativa e caracterizou-se como pesquisa-ação. Os procedimentos metodológicos contemplaram estudos documentais, observação participante e pesquisa-intervenção na escola lócus do estágio. O contexto de inclusão escolar tratou-se de duas turmas dos Anos Iniciais do Ensino Fundamental de uma escola de Educação Básica da Rede Pública de Ensino em que há estudantes com deficiência matriculados. A pesquisa se constituiu a partir de cenas da prática profissional docente relatada pelos estagiários, com foco na ação dos professores das áreas curriculares, do atendimento educacional especializado, dos próprios acadêmicos em estágio, bem como da relação estabelecida entre os estudantes dos anos iniciais do ensino fundamental. A prática profissional em contexto de inclusão escolar possibilitou aos estagiários a reflexão sobre a ação docente dos profissionais do ensino comum e especializado, a articulação teoria e prática, a compreensão da deficiência como própria da diversidade humana de modo que reiteramos a importância de percursos formativos na licenciatura que contemplem a área da educação especial.
Desafíos y estrategias en la implementación de metodologías agiles en proyectos informáticos
Authors: Chacha-Cajamarca Fabiola Jescenia , Cordero- Guzman Diego Marcelo , Ramón Poma Glenda Maricela
Published: June 2024

En un entorno empresarial cada vez más competitivo y dinámico, la adopción de metodologías ágiles en proyectos informáticos es crucial para asegurar la eficiencia y el éxito en la entrega de productos y servicios de software. Este artículo se enfoca en analizar los desafíos específicos que las organizaciones enfrentan al implementar estas metodologías, y para ello se realiza una entrevista detallada a empleados clave para comprender a fondo estos desafíos y las estrategias utilizadas para superarlos. El desarrollo de este estudio se basa en una investigación cualitativa, descriptiva, de campo y corte transversal. La investigación de campo adoptada en este estudio se basa en la entrevista como técnica de recolección de datos cualitativos. Inicialmente, se explora el trasfondo esencial de las metodologías ágiles, enfatizando su carácter iterativo e incremental, su enfoque centrado en el cliente y su capacidad para adaptarse ágilmente a los cambios en los requisitos del proyecto. Luego, se profundiza en los desafíos más comunes que surgen durante la implementación de estas metodologías, como la resistencia al cambio organizacional, la necesidad de experiencia y conocimiento en los equipos, y la gestión de la incertidumbre inherente a los proyectos ágiles. Se destaca la importancia crítica de una cultura organizacional sólida y flexible que fomente la agilidad, promoviendo la colaboración activa, la transparencia en la comunicación y un enfoque continuo en el aprendizaje y la mejora. Además, se subraya la necesidad de una formación y capacitación efectivas para los equipos, junto con la implementación de prácticas de gestión ágil de proyectos y el uso adecuado de herramientas y tecnologías modernas.
Ossetian traditional dance nærton simd (the cult aspect)
Authors: Салбиев Т.К.
Published: June 2024

Ценным источником для изучения осетинского культа огня предлагается считать танец Нæртон симд. Исполняемый вокруг костра, этот танец был приурочен к праздникам новогоднего цикла, что позволяет связывать его семантику с эсхатоло- гическим мифом. Одновременно танец оказывается хореографической иллюстрацией эпического цикла «Гибель нартов», что получает обоснование в самом рисунке и драма- тургии танца, в составе его участников, в используемых в нем атрибутах.

The Nærton Simd dance is proposed to be considered a valuable source for the study of the Ossetian fire cult, recognized as one of the central ones for Ossetian traditional culture. Performed around a fire, this dance was timed to holidays of the New Year's cycle and therefore one can connect its semantics with eschatological myth. At the same time, the dance turns out to be a choreographic illustration of the epic cycle “The Downfall of the Narts,” which is justified in the scheme and the dramaturgy of the dance, in the composition of its participants and in the attributes used in it.
Russian academic science and the first archaeological studies of Kabardian material culture
Authors: Кагазежев Ж.В.
Published: June 2024

Статья посвящена началу археологического исследования российской ака- демической наукой материальной культуры кабардинцев. Важнейшую роль в указанном процессе сыграла Императорская археологическая комиссия, благодаря которой были сделаны первые масштабные археологические исследования территории расселения кабардинцев. Новизна исследования состоит в том, что показывается ведущая роль Императорской археологической комиссии в исследовании кабардинских курганных за- хоронений и делается анализ их материальной культуры согласно территориальному принципу. Данные материалы имеют большое значение в реконструкции этнополити- ческой ситуации в Центральном и Восточном Предкавказье в эпоху позднего Средне- вековья. Актуальность обусловлена необходимостью активизации использования археологических данных при рассмотрении особенностей материальной культуры и эт- нополитической ситуации на Северном Кавказе в эпоху позднего Средневековья.

The article is devoted to the beginning of the archaeological research of the Kabardian material culture by the Russian academic science. The most important role in this process was played by the Imperial Archaeological Commission, thanks to which large-scale archaeological research of the Kabardian settlement area was initiated. The novelty of the study lies in the fact that it shows the leading role of the Imperial Archaeological Commission in the study of Kabardian burial mounds and analyzes their material culture according to the territorial principle. These materials are of great importance in the reconstruction of the ethnopolitical situation in the Central and Eastern Pre-Caucasus in the Late Middle Ages. The relevance is due to the need to intensify the use of archaeological data when considering the features of material culture and the ethnopolitical situation in the North Caucasus in the late Middle Ages.
On the issue of the citizenship of the South Ossetians of the Georgian kings
Authors: Дзидзоев В.Д.
Published: June 2024

В статье рассматривается малоизвестная историческая проблема, свя- занная с периодом, когда южные осетины были подданными грузинской феодальной мо- нархии. Поднимаемая здесь проблема представляется не только актуальной с точки зрения отечественной истории, но и интересной с общественно-политических позиций сегодняшнего дня, когда взаимоотношения грузин и осетин существенно деградировали не только из-за геноцида, устроенного грузинскими властями в отношении южных осе- тин в 1920, 1989–1992 и 2008 гг., но и полного и окончательного отделения Южной Осе- тии от Грузии. Статья носит дискуссионный характер, но факты, приводимые здесь, представляются автору убедительными, аргументированными и доказательными.

The article examines a little-known historical problem related to the citizenship of South Ossetians of the Georgian feudal monarchy and Georgian kings. The problem raised here seems not only relevant from the point of view of national history, but also interesting from the sociopolitical point of view of today, when the relationship between Georgians and Ossetians has deteriorated significantly not only because of the genocide committed by the Georgian authorities against the South Ossetians in 1920, 1989- 1992 and 2008, but also the complete and final separation of South Ossetia from genocidal Georgia. The article is of a controversial nature, but the facts presented here by the author seem convincing, reasoned and evidence-based.
Creating Assessment Rubrics for Final Teacher Education Degree Projects: A Qualitative Case Study
Authors: Fernández Garcimartín Carla , López Pastor Víctor Manuel , Fuentes Nieto Teresa , Hortigüela Alcalá David
Published: June 2024

This paper analyzes the process of creating the assessment instruments for the Final Year Project (FYP) by education faculty based on the opinions of the lecturers. Qualitative methodology was used, with a case study design and the in-depth interview as a data collection technique. Four lecturers participated as relevant informants. The results show that: (a) the faculty decided to create the instruments due to the lack of clear assessment criteria among the lecturers in the first years (2009-2015); (b) work was carried out on three assessment instruments over two years (2015-2017): a tutor's report (without grade), a document rubric (80% of the mark), and an oral presentation rubric (20% of the mark). It is concluded that the assessment instruments were created through the necessity of the faculty to achieve a more objective and effective FYP assessment. The creation of the instruments followed some steps to encompass the degree competencies and the objectives, types, and criteria of the FYP. The paper presents the process of creating assessment instruments and the advantages of their use, specifically the treatment of rubrics as the main assessment instrument. It seems necessary to carry out further research on assessment instruments for dissertations and theses, given their proven relevance.
APLIKASI GAME EDUKASI PEMBELAJARAN SENI BUDAYA MENGGUNAKAN LINEAR CONGRUENTIAL GENERATOR (LCG)
Authors: Ahmad Thariq  , Mita Paramitha
Published: June 2024

Seni budaya memiliki beberapa jenis salah satunya yang berkembang di maluku secara turun temurun ialah musik tradisional. Kurangnya pengetahuan siswa tentang pengenalan musik tradisional salah satunya disebabkan karena terbatasnya fasilitas dan kurangnya jam pembelajaran seni budaya di sekolah. Adanya penelitian ini bertujuan untuk membuat sebuah inovasi game edukasi pembelajaran seni budaya yang lebih modern dengan memanfaatkan teknologi smartphone. Pembuatan game edukasi ini akan menggunakan model MDLC (multimedia development life cycle) dengan menggunakan bahasa pemograman C# dan unity 3D sebagai software. Selain menampilkan beberapa materi tentang pembelajaran seni budaya dalam hal ini pengenalan alat musik tradisonal maluku didalam aplikasi terdapat juga quiz yang menampilkan 10 soal yang teracak dengan total soal sebanyak 20 soal. Metode yang digunakan dalam mengacak soal yaitu linear congruential generator (LCG). Dengan memanfaatkan linear congruential generator (LCG) dapat menghasilkan nomor soal yang teracak sehingga para siswa memiliki soal dengan nomor berbeda dan proses pembelajaran di sd negeri 9 namlea menjadi lebih efektif. Aplikasi ini bisa menjadi media pembelajaran bagi siswa di sd negeri 9 namlea, karena menyediakan informasi pembelajaran seni budaya mengenai jenis-jenis alat musik tradisonal di maluku serta dilengkapi dengan quiz yang dapat dimainkan oleh user.
ANALISIS AUDIO AMBISONIC DALAM MENENTUKAN ARAH BUNYI SEBAGAI RANCANGAN PEMBUATAN AUDIO FILM UNTUK DISABILITAS NETRA
Authors: Surya Ibrahim Adi , Della Dwinanti Sumpena  , Bowo Andrean
Published: June 2024

Audio Ambisonic merupakan teknik perekaman dan pemutaran suara yang dapat merepresentasikan arah dan jarak sumber suara dalam ruang tiga dimensi. Audio Ambisonic dapat digunakan untuk menciptakan audio untuk film yang memberikan pengalaman mendalam bagi penonton, terutama bagi individu dengan gangguan penglihatan yang mengandalkan informasi spasial dari suara. Penelitian ini bertujuan untuk menganalisis Audio Ambisonic menggunakan DAW Studio One dan plugin Audio Ambisonic Waves NX360 untuk menentukan arah suara sebagai desain awal pembuatan audio untuk individu dengan gangguan penglihatan sebagai media hiburan. Arah suara adalah keunggulan teknologi Audio Ambisonic yang perlu dianalisis karena mencakup arah 360 derajat atau tiga dimensi. Penelitian ini menggunakan metode eksperimental dengan membuat sampel audio menggunakan berbagai teknologi Ambisonic dalam hal arah dan jarak sumber suara, kemudian menguji efeknya pada persepsi spasial dan pendengar dengan gangguan penglihatan.
 
                                                                                                                 
Kata Kunci: Ambisonic, disabilitas netra, arah bunyi, audio film
SISTEM PENDUKUNG KEPUTUSAN PENYEWAAN KOS-KOSAN DI DESA ANJANI MENGUNAKAN METODE SIMPLE ADAPTING WEIGHTING (SAW) BERBASIS WEB
Authors: Zulkarnaen Zulkarnaen , Antarul Aziz
Published: June 2024

The existence of boarding houses around public facilities is very desirable and beneficial for students who come from outside the area to study at university. However, the many choices of boarding houses with different prices, facilities and distances make students confused when choosing a temporary place to live. To overcome this problem, the web-based Simple Additive Weighting (SAW) method is used in a decision support system. This system provides recommendations or suggestions for boarding houses that match the criteria entered by the user. The user will input criteria and alternatives into the system, then the system will carry out a calculation process to provide a list of recommended boarding places. The research results show that this system can help prospective boarding house renters in choosing recommended alternative boarding places based on criteria and user input using the SAW method. With this system, students can more easily find temporary housing that suits their needs.
SALMONELLA IN WILD BOARS (SUS SCROFA): INFLUENCE OF HUNTING AND DRESSING PROCEDURES ON MEAT SAFETY
Authors: Petrovic Jelena , Mirčeta Jovan , Velhner Maja , Stojanov Igor , Ratajac Radomir , Prodanov-Radulović Jasna
Published: June 2024

Salmonella spp. is considered as a high-priority foodborne hazard for control in wild boar meat. This comprehensive study about Salmonella spp. in population of wild boars in Serbia was conducted with an aim to assess the influence of hunting and dressing procedures on the spread of Salmonella on wild boar carcasses and to examine the molecular similarities of strains isolated from wild boars. Samples from wild boars from twelve hunting estates in South-West Vojvodina, Serbia, were taken from 425 hunted animals, which was 25.3% of the total wild boar population in all hunting estates. Three samples were taken from each animal’s skin swabs, feces, and carcass meat swabs. A total of 1,275 samples were examined using standard ISO protocols. Subtyping of the isolates was performed and compared using Pulsed-field gel electrophoresis (PFGE). Salmonella prevalence was 4.2%, and Salmonella Enteritidis was the dominant serotype (74.5%). Carcass meat contamination originated from the feces of the same animal. Two or more entrance wounds, damage of the abdominal cavity caused by non-expert shooting were factors found to increase Salmonella contamination on the skin and/or on carcass meat. Rain during the hunting and practice of diaphragm and peritoneum removal and the evisceration being performed on the ground/floor or in hanging position did not lead to increase in Salmonella contamination on the meat. Although the determined prevalence was not high in wild boars compared to farm pigs, it is possible that Salmonella entered the food chain through contaminated meat. Therefore, the importance of good hunting and hygiene practice in handling and dressing wild boar carcasses should not be underestimated.
Synergistic Effects of Content Marketing and Influencers Marketing on the Formation of Brand Awareness and Purchase Interest of TikTok Shop Users (Cirebon City Case Study)
Authors: Izza Ahmad Mudrikul , Ardiansyah Muhammad Nur , Barkah Fajar , Romdonny Jefry
Published: June 2024

This research aims to investigate the synergistic influence between Content Marketing and Influencer Marketing on the formation of Brand Awareness and Purchase Interest of TikTok Shop users in Cirebon City. The aim is to analyze the impact of these two marketing strategies on brand awareness and purchase intention and to test their influence significantly. The research method uses a quantitative approach using research instruments and statistical analysis, especially with SPSS version 24. Samples were taken through non-probability sampling with purposive sampling criteria for respondents aged 17-30 years who are users of the TikTok application in the Cirebon area. Research variables include Content Marketing (X1), Influencer Marketing (X2), Brand Awareness (Y1), and Purchase Intention (Y2). The analysis results show that Content Marketing and Influencer Marketing have a significant influence on Brand Awareness and Purchase Interest, with a high R Square value indicating the influence of these variables on the outcome. In conclusion, this research found that Content Marketing and Influencer Marketing play an important role in forming brand awareness and interest in purchasing products on the TikTok Shop. Recommendations include strengthening content-based marketing strategies and collaboration with influencers, as well as paying attention to the relationship between Brand Awareness and Purchase Interest to improve sales performance through the TikTok Shop platform. This research can be the basis for further research regarding the influence of Content Marketing and Influencer Marketing in the context of digital marketing.
Quick Response Crisis Communication Strategies Insights from Public Relations PT. KAI DAOP 2 Bandung's Train Accident Response
Authors: Cintia Cintia , Susanti Tantri Aditya , Amanda Grisha , Nuruzzaman Muhammad , Lestari Aghnia Dian
Published: June 2024

A crisis that occurs in a company has the potential to damage the company's reputation. However, if the crisis can be handled properly, then the crisis will not harm the company. The purpose of this research is to find out the crisis communication steps and efforts made by the Public Relations of Daop 2 Bandung in dealing with the crisis situation caused by the train accident. Researchers use a descriptive analysis approach because it is considered capable of describing something clearly and each part can be studied one by one, so that the facts of a case can be revealed transparently. Data collection techniques in the form of interviews, in this study the data source consists of primary data and secondary data. Primary data was obtained from interviews with Mr. Ayep Hanapi as Public Relations Manager of PT KAI Daop 2 Bandung. The results showed that PT KAI Public Relations has made several efforts to maintain the company's image, namely: First, pre-crisis PT KAI applies the zero accident principle by increasing employee competence and discipline as well as maintaining facilities and infrastructure. Second, PT KAI's crisis team collaborates with stakeholders, provides solutions, is responsive in serving the media by preparing accurate data and fact information. Third, post-crisis to improve the image by providing compensation to employees and accident victims and conducting evaluations to improve train safety and security in the future.
Cập nhật chẩn đoán và điều trị tiền đái tháo đường
Authors: Nguyễn Hải Thủy
Published: June 2024

Tiền đái tháo đường (ĐTĐ) là tình trạng tăng glucose máu mức trung gian với các chỉ số glucose máu trên mức bình thường nhưng dưới ngưỡng chẩn đoán ĐTĐ. Tiền ĐTĐ là  trạng thái đặc trưng bởi rối loạn đường huyết lúc đói (IFG) và/hoặc rối loạn dung nạp glucose (IGT). Mặc dù tiêu chuẩn chẩn đoán tiền ĐTĐ chưa thống nhất giữa các tổ chức Y học quốc tế nhưng tiền ĐTĐ vẫn là trạng thái có nguy cơ cao phát triển bệnh ĐTĐ với tỷ lệ hàng năm thay đổi từ 5% -10%. Các bằng chứng quan sát cho thấy mối liên quan giữa tiền ĐTĐ và các biến chứng của bệnh ĐTĐ như bệnh thận ĐTĐ giai sớm, bệnh thần kinh ĐTĐ, bệnh võng mạc ĐTĐ sớm, nguy cơ bệnh mạch máu lớn và gần đây ghi nhận bệnh não ĐTĐ thông qua suy giảm thần kinh nhận thức. Bên cạnh đó một số nghiên cứu cũng đã ghi nhận hiệu quả của các biện pháp can thiệp lối sống và xử dụng thuốc liên quan đến phòng ngừa bệnh ĐTĐ với mức giảm nguy cơ từ 40% -70% ở đối tượng người lớn mắc tiền ĐTĐ. Sự hiểu biết về tiền ĐTĐ có thể giúp xác định bệnh được sớm hơn, cho phép can thiệp sớm hơn, có khả năng làm giảm số lượng người bệnh tiền ĐTĐ sẽ phát triển bệnh ĐTĐ và các biến chứng ĐTĐ. Ngăn ngừa sự tiến triển từ tiền ĐTĐ thành bệnh ĐTĐ típ 2 bằng can thiệp lối sống và các nhóm thuốc (Metformin, Ức chế a-glucosidase, đồng vận thụ thể GLP1 glucagon like peptide 1), Thiazolidinediones). Việc sử dụng thuốc cần cân nhắc giữa chi phí, tác dụng phụ và hiệu quả lâu dài. Metformin có cơ sở bằng chứng mạnh mẽ nhất và chứng minh tính an toàn lâu dài như một liệu pháp dược lý để phòng ngừa bệnh ĐTĐ. Dựa trên các kết quả từ Chương trình Phòng chống Đái tháo đường (DPP), Metformin nên được khuyến nghị như một lựa chọn cho những người tiền ĐTĐ có nguy cơ cao (ví dụ: người có tiền sử ĐTĐ thai kỳ, < 60 tuổi, BMI ≥25 kg/m2 đối với người Châu Á , có một trong các yếu tố nguy cơ (HbA1c > 6%, IFG cộng với IGT, huyết áp cao, nồng độ HDL.C < 0,9 mmol /L, TG > 2,52 mmol/l và có người thân trực hệ bị ĐTĐ)
Điều trị nhiễm toan acid lactic ở bệnh nhân đái tháo đường
Authors: Trần Thừa Nguyên
Published: June 2024

Nhiễm toan acid lactic là một tình trạng tích tụ quá nhiều acid lactic trong máu, đây là trường hợp toan chuyển hoá thường gặp, nhất là trong những trường hợp đang bị bệnh cấp nặng, nhiễm toan acid lactic như một biến chứng của bệnh chính. Trong thực tế lâm sàng người ta chia ra 2 týp: Nhiễm toan acid lactic týp A thường do thiếu oxy ở mô, týp B do phối hợp với các bệnh cảnh khác. Điển hình nhiễm toan acid lactic xảy ra do chuyển hóa glucose trong bối cảnh thiếu oxy ở mô hoặc do gan không đủ khả năng loại bỏ acid lactic. Nhiễm toan nặng có thể làm giảm sức co bóp của tim, gia tăng sự đề kháng của mạch máu phổi, cơ tim tăng nhạy cảm dể dẫn đến loạn nhịp, tăng Kali máu, ức chế sự chuyển hóa ở tế bào hoặc ở mức phân tử. Tỷ lệ tử vong cao, từ 40 - 60% các trường hợp.
Cập nhật thuốc điều trị đái tháo đường: Dưới góc nhìn dược lý lâm sàng
Authors: Lê Chuyển , Nguyễn Thành Tín
Published: June 2024

Mục tiêu của quản lý Đái tháo đường (ĐTĐ) típ 2 là cung cấp phương pháp điều trị cá nhân hóa để cải thiện hiệu quả kiểm soát đường huyết để ngăn ngừa biến chứng và giảm tác dụng phụ của thuốc. Điều này được đánh giá dựa trên góc độ dược lý lâm sàng, thông qua các thử nghiệm ngẫu nhiên có đối chứng phân tích tổng hợp và các nghiên cứu quan sát thực tế đặc biệt là các nghiên cứu ở những bệnh nhân có nguy cơ cao bệnh lý tim mạch và thận. Sự cân bằng lợi ích - nguy cơ của các thuốc điều trị đái tháo đường cổ điển, chẳng hạn như metformin, sulfonylureas và glitazones đã được xem xét lại. Việc cập nhật các thuốc hạ đường huyết mới đã chứng minh sự an toàn trên tim mạch, tác dụng bảo vệ tim mạch và thận. Hiệu quả, tính an toàn của các liệu pháp phối hợp và tiến bộ trong liệu pháp insulin cũng là nội dung được đề cập đến.