bluuebunny/crossref_metadata_2025 huggingface dataset:
Lecturers` leadership style influences voluntary: It is a democratic matter?
Authors:   Commerce Department, Polytechnic of Tuanku Sultanah Bahiyah, Kulim Hi-Tech Park, 09000 Kulim, Kedah, Malaysia, Jaafar Syaiful Baharee , Bahaudin Mohd Fahmee ,   Commerce Department, Polytechnic of Tuanku Sultanah Bahiyah, Kulim Hi-Tech Park, 09000 Kulim, Kedah, Malaysia, Md. Zuki Mohd Huzaimi ,   Commerce Department, Polytechnic of Tuanku Sultanah Bahiyah, Kulim Hi-Tech Park, 09000 Kulim, Kedah, Malaysia
Published: September 2023

Leadership characteristics can influence employee motivation to do the task voluntarily. Task accomplished without delay that is beneficial to the organization based on costs savings and increase profit. The employee conforms to the leader who has similari chemistry. Hence, the lecturers will be happy to work with the department head when they like the leadership characteristic. They are willing to do the work voluntarily, particularly non-academic activities. The objective of this study is to examine the lecturers` leadership style influences their volunteers. The sample of this study consists of various departments of the Polytechnic of Tuanku Sultanah Bahiyah. The lecturer is made up of the Department of Commerce (JP), Civil (JKA), Electrical (JKE), Mechanical (JKM), Mathematics, Science and Computing, and General studies The findings show that the lecturers` leadership styles are democratic style rather than autocratic. The lecturers` are interested to involve in the decision-making process has led to voluntary. The lecturer takes full responsibility for the decision because they are part of that.
The Effects of Neurofeedback Training on Emotional Arousal in Individuals Varying on Psychopathy
Authors:   , Buurmans Emma
Published: September 2023

Individuals with high psychopathy show habitual emotional nonresponding tendencies, which are thought to enable the antisocial patterns of behaviour often exhibited by these individuals. The current study aimed to assess the potential of neurofeedback training as an emotion-processing intervention in psychopathy by investigating its effects on emotional arousal in individuals of varying psychopathy levels. The neurofeedback protocol was designed to train a pattern of EEG activity indicative of emotional arousal, based on the Emotional Arousal Pattern (EMAP) dataset. Participants completed two neurofeedback sessions, each consisting of two 10-minute training blocks. Emotional arousal measures included self-reported experience of high-arousal emotions and Emotion-Induced Blindness (EIB) task performance indicative of arousal-induced emotional distraction. Emotional arousal was measured before the first neurofeedback session, following the first neurofeedback session, and following the second neurofeedback session. Psychopathy was measured with the Psychopathic Personality Inventory–Revised–40 (PPI–R–40) self-report questionnaire. No significant increases in self-reported emotional arousal, nor arousal-induced emotional distraction, were observed from pre- to post-neurofeedback training, regardless of psychopathy level. It was concluded that the neurofeedback training protocol used in the current study was insufficient to increase arousal, likely due at least in part to methodological limitations. Discussed issues include the difficulty of achieving neurofeedback task objectives given limited training time, the influence of non-specific intervention factors on experimental task performance, and the insensitivity of the self-report measure to changes in arousal. Based on these issues, several recommendations are made for improving the neurofeedback paradigm in future research, so that its potential for training emotional arousal can be better determined both generally and in the context of psychopathy.
New methods for the discovery of natural products from understudied and uncultivated bacterial phyla
Authors:   , Nowak Vincent
Published: September 2023

Natural products and their derivatives account for the majority of approved drugs. New antibiotics are urgently needed to combat increasing antibiotic resistance and fatalities caused by it. Traditional cultivation-based approaches, like the Waksman platform, led to the discovery of several antibiotics and other drugs but were ultimately hampered by rediscovery of the same molecules. The marine environment, and in particular marine sponges, have long been a source of natural products including approved drugs and drugs currently undergoing clinical development. Bacteria associated with marine sponges are often responsible for the production of natural products rather than the eukaryotic organism itself. This work used methods including metagenomic sequencing and metagenomic libraries to identify, analyse and target putative natural products encoded in the genomes of bacteria, mainly those associated with marine sponges. Initially a bioinformatic workflow (MetaSing) was developed for the analysis of metagenomic sequencing datasets with the main aim being the attribution of biosynthetic gene clusters (BGCs) to individual metagenome-assembled genomes (MAGs). MetaSing was used to analyse 16 sponge metagenomes from various geographic locations resulting in the identification of 643 MAGs and 2,670 BGCs, 70.79% of which were attributed to a MAG. Phyla identified as encoding significant biosynthetic potential include Proteobacteria and Nitrospirota as well as lesser-studied phyla that are difficult to cultivate, such as the Candidatus Latescibacterota, Verrucomicrobia and Acidobacteriota. A metagenomic cosmid library derived from the marine sponge M. hentscheli was then sequenced using Illumina short reads and Nanopore long reads to quantify the capture of biosynthetic potential and develop a method for efficient recovery of BGCs. This analysis demonstrated that while close to half the BGCs are completely captured in the cosmid library, several are incompletely captured or not captured at all. Conversely, novel BGCs not identified from metagenomic sequencing were identified in the cosmid library sequencing data. The BGC recovery method was then applied to recover three acidobacterial BGCs from two marine sponge cosmid libraries and 11 lasso peptide BGCs from New Zealand soil libraries. Isolated cosmids were retrofitted and conjugated into heterologous expression hosts but only one BGC elicited putative production of non-native compounds.
Informal: An investigative study into complex behavioral modelling.
Authors:   , Salud Juan
Published: September 2023

The following research explores the computational modelling of informal settlement growth and characteristics, and represents the outputs using a visual, representational, format.

To achieve this, a rule-based algorithm within a digital environment was developed, with the introduction of complexity through incremental steps justified in response to comparing the resemblance of simulation to real-life observations, statistical data, and relevant cases. Furthermore, the performance of the developed self-iterative model as an analytical tool was analyzed in terms of its effectiveness in responding to the detriments of informal settlements, by identifying areas of improvement.

The outcome of this experiment revealed that whilst singular actions can be defined by basic rulesets, the accuracy of behavioral modelling requires more complexity in the simulation, with constant adaptability, and multiple responses triggered by various situations when implemented in certain environments. The performance of a Cellular Automaton as an analytical tool appeared to provide appropriate suggestions but is, however, limited by the complexity of the initial model with regards to comprehensive validity.

Overall, the work suggests that modelling by rulesets defined by observations and statistics provides an alternative approach that analyses a settlement and its buildings and spaces by reference to the relevant data.

This research emphasizes the capabilities of behavioral simulations to inform understanding of settlements, settlement layouts, and the challenges in the imitation of complex human nature and actions in defined algorithmic rulesets.
Hacia una investigación decolonial senti-accionada y reflexiva en vínculo y compromiso con la vida
Authors: Briñez Yamile Alvira
Published: September 2023

O presente artigo é fruto de pesquisa de doutorado que sintetiza o processo de construção e os principais elementos que constituem a proposta de abordagem teórica, epistêmica e metodológica, com um componente político-pedagógico que denomino: Investigação decolonial senti-acionada e reflexiva em vínculo e compromisso com a vida. Essa abordagem é pensada e executada a partir de uma posição crítica como pesquisadora e psicóloga social latino-americana, com uma prática política e acadêmica comprometida com diferentes comunidades camponesas originárias da região andina do Peru e Equador. Essas comunidades lutam pela defesa da água e da vida em seus territórios, diante da imposição de megaprojetos extrativistas e predatórios favorecidos pelas políticas neoliberais inerentes ao capitalismo global.
Effects of annealing temperature and duration on mechanical properties of PLA plastics produced by 3D Printing
Authors: KARTAL Fuat , KAPTAN Arslan
Published: September 2023

This study aims to investigate the effect of annealing temperature and duration on the mechanical properties of PLA (polylactic acid) plastics produced by a 3D (three-dimensional) printer. For this purpose, PLA samples were annealed at 70 °C, 85 °C, and 100 °C temperatures and for 30, 60, and 90-minute durations. As a result of the study, it was shown that the annealing process has a significant effect on the mechanical properties of PLA plastics. Compared to the control sample, an increase of 48% in tensile stress, 78% in the modulus of elasticity, 28% in Shore D hardness value, and 41% in bending stress was observed. In particular, the highest mechanical properties of PLA plastics were reached after applying the annealing process at 85 °C temperature and for 90 minutes. These results demonstrate the advantages of using 3D printers in the production of products requiring high durability in industrial applications. Moreover, the study findings provide an important method for optimizing the mechanical properties of materials produced with 3D printer technology.
Optimisation of design parameters of the finned tube heat exchanger by numerical simulations and artificial neural networks for the condensing wall hang boilers
Authors: AVCI Hasan , KUMLUTAŞ Dilek , ÖZER Özgün , YÜCEKAYA Utku Alp
Published: September 2023

This research investigates the use of computational fluid dynamics (CFD) and artificial neural networks (ANNs) to optimise the design of finned tube heat exchangers for use in condensing wall-mounted boilers (WHBcs). Fin height, thickness, and distance are selected as the input design parameters, and the internal volume of the heat engine is modelled using the CFDHT (CFD and heat transfer) method. Different ANN structures are trained and tested on the resulting data to identify the optimal training process. The trained ANN is then used to predict various output parameters, including total heat transfer on the inner surface of the tube, maximum temperature on the fins, total heat transfer per unit volume of the heat exchanger, and pressure drop between the inlet and outlet of the internal volume. The optimal design scenarios are evaluated based on design criteria, and the ANN is found to have good statistical performance, with an average accuracy of 1.00018 and a maximum relative error of 9.16%. The ANN is able to accurately estimate the optimal design case.
Effect of heat treatment on the performance of 30MnB4 steel for being used as grade 10.9 bolt material
Authors: GÜVEN Onur , ERDOGAN Yasemin
Published: September 2023

Due to technological advancements, alloy steels are now widely used in producing high-strength bolts through various heat treatments. One of the essential features desired in bolts is their strength, as they are subject to heavy loads. This strength is referred to as bolt quality, and interest in heat treatment methods applied to increase the strength of alloy steels is increasing. The mechanical properties achieved from different heat treatment methods and chemical compositions vary. This study aimed to impart the mechanical properties of grade 10.9 steel bolts onto 30MnB4 steel by applying different heat treatments. The effects of tempering temperature on tensile strength, yield strength, elongation at break, reduction in cross-sectional area at break, hardness, and notch impact values at -20°C were examined by passing the prepared samples through five different tempering processes after preheating, annealing and quenching processes. The results revealed that the mechanical properties of grade 10.9 steel bolts were imparted to 30MnB4 steel at all tempering temperatures applied within the scope of the study. Yield strength, tensile strength, hardness, and -20°C notch impact values increased as tempering temperature decreased, while elongation at break decreased. This study adds 30MnB4 steel to the literature as an alternative material that can be used to produce grade 10.9 steel bolts. In addition, mechanical properties obtained depending on tempering temperatures have also revealed the usability of 30MnB4 steel for different applications requiring high strength and toughness values.
Performance comparison machine learning algorithms in diabetes disease prediction
Authors: GÖDE Aslı , KALKAN Adnan
Published: September 2023

Machine learning has been widely used in the field of medicine with the developing technology in recent years. Machine learning is a field that is also used in the diagnosis of diabetes and helps experts make decisions. Diabetes is a lifelong disease that is common worldwide and in our country. The main purpose of this study is to diagnose diabetes early using different machine learning classification algorithms. Another purpose of the study is to compare the success of the machine learning models used.
Early diagnosis of diabetes allows to lead a healthy and normal life. In this context, it has been tried to diagnose diabetes early by using the machine learning techniques Decision Tree, Random Forests, K-Nearest Neighbor and Support Vector Machines classifiers on the Pima Indians Diabetes dataset. The dataset includes 9 features and 768 samples. Success evaluation of classifiers was made using Accuracy, Precision, Recall, F1-Score and AUC metrics. Random Forests gave the best results with 80 percent accuracy. This paper is to examine the association of different machine learning techniques usage, diabetes data diagnostic capabilities, diagnosis of diabetes in women diabetes patients and comparison of performances for machine learning techniques. Implications for theory and practice have been discussed. In this study, comparisons were made using different algorithms from the classification algorithms used in the literature and contributed to the literature in this field.
Effect of diesel injection pressure for enhancing combustion and reducing mechanical vibration and noise emissions in a non-road diesel engine
Authors: GÜLCAN Halil Erdi , GÜLTEKİN Nurullah , CİNİVİZ Murat
Published: September 2023

In this study, the combustion, performance, emissions, noise, and vibration characteristics of a single-cylinder, four-stroke, air-cooled diesel engine used for non-road purposes were investigated by controlling different injection pressures with a common rail fuel injection system. The aim of this study is to enhance the combustion performance and improve the existing noise and vibration levels of this commonly used non-road diesel engine in fields such as agriculture, wetlands, and the construction sector by optimizing the injection pressure. The experiments were conducted under low and medium load conditions and at a constant engine speed. The single-cylinder, non-road engine's fuel injection system was controlled using a common rail fuel delivery system, and four different diesel injection pressures (250, 300, 350, and 400 bar) were utilized. The experimental results have shown that the combustion performance, emissions, noise, and vibration values of the non-road diesel engine improved with an increase in diesel injection pressure (DIP). Increasing DIP led to higher maximum combustion pressures and resulted in reductions of HC, CO, and smoke emissions by up to 25%, 48%, and 59%, respectively. Vibration values also decreased by up to 25%.
Direct determination of glyphosate and its metabolite in the plant raw material and environmental objects by chromatography-mass spectrometry
Authors: Sorokin A. V.
Published: September 2023

Glyphosate is a popular herbicide often used for desiccation of crops. The use of glyphosate-based chemicals leads to the contamination of agricultural products, soils, surface and groundwater. For safety control of raw materials of the plant origin and environmental objects, a technique based on the tandem chromato-mass-spectrometry was developed to provide for the quantitative determination of glyphosate and aminomethylphosphonic acid (AMPA) without prior derivatization. The technique is characterized by a relatively simple and cost-effective sample preparation procedure. The compounds are extracted from plant raw materials with an acetic acid solution of methanol in water, in the presence of 2-aqueous disodium salt of ethylenediamine-N,N,N’,N’-tetraacetic acid (EDTA-Na2) and dichloromethane. Extraction of analytes from water samples is carried out in the presence of EDTA-Na2 and acetic acid; whereas their extraction from soil samples is carried out with a weak solution of ammonia. The extracts are purified by solid phase extraction (SPE), and proteins are precipitated with acetonitrile. Linear-dynamic ranges of glyphosate and AMPA determination are characterized by calibration curves with correlation coefficients (R) ≥0.99. The working range of glyphosate and AMPA determination in raw materials of plant origin was from 0.1 to 5.0 mg/kg; in surface and ground water from 0.001 to 0.05 mg/liter (glyphosate) and from 0.002 to 0.05 mg/liter (AMPA); in soils from 0.02 to 0.8 mg/kg (glyphosate) and from 0.04 to 0.8 mg/kg (AMPA). The values of the relative standard deviation range from 1.8 to 19.5%, with recovery levels ranging from 80.5 to 108.1%. The achieved values of the determination limits are consistent with the maximum permissible levels indicated in TR CU 015/2011 and SanPiN 1.2.3685–21.
Restoration of the orientation distribution function for materials with low lattice and sample symmetry using the harmonic method
Authors: Kolyanova A. S.
Published: September 2023

A lot of the properties polycrystalline materials depend on their crystallographic texture. The most complete information about the texture can be obtained from the orientation distribution function (ODF). We present the results of recovering ODF using series expansion technique for materials with low crystal and sample symmetry. The technique of ODF restoration is based on its Fourier series expansion with symmetrical spherical harmonic functions. Real spherical harmonics which are linear combinations of general spherical harmonics were used. The model single-component texture as well as the real texture of magnesium alloy sample subjected to equal-channel angular pressing have been studied. Textures are characterized by hexagonal crystal symmetry and triclinic sample symmetry. In both cases RP-factors and ODF calculation errors that were used as reliability criteria of ODF reconstruction showed good agreement between the calculated and experimental data. It was also revealed that the ODF of a magnesium alloy sample subjected to equal-channel angular pressing contains two texture components (1216)[1211] and (1216)[1211] with maximum intensity values of 13.81 and 2.23, respectively. The results obtained can be used for texture studies of ceramics, rocks and other non-metallic materials characterized by a lower symmetry.
Study of magnetoelastic demagnetization of locally magnetized steel
Authors: Novikov V. F. , Kulak S. M. , Muratov K. R. , Probotyuk V. V.
Published: September 2023

To improve the accuracy of determining mechanical stresses in steel by the method of magnetoelastic demagnetization (magnetoelastic memory), the magnetoelastic sensitivity of the material to elastic stresses is additionally measured by applying or removing an additional load of a known value. We present the results of studying the magnetoelastic demagnetization of locally magnetized steel by varying stresses of the uniaxial tension or compression against a background of the base load. The magnetoelastic sensitivity of the steel in a loaded state to variable stresses has been assessed. It is shown that the determination of the magnetoelastic sensitivity of the steel to variable loads makes it possible to improve the accuracy of estimating base stresses in the steel structure using magnetoelastic methods. It is revealed that a decrease in the strength of the magnetic scattering field of the local residual magnetization (LRM) of the steel after variable loading (or unloading) exponentially depends on the magnitude of the base stresses. The possibility of controlling the uniaxial mechanical stresses in steel structures in the magnetoelastic memory mode which is based on the dependence of the strength of magnetic scattering field of the local residual magnetization of the steel on the uniaxial stresses is shown. A method for monitoring uniaxial stresses in the elements of steel structures by the method of magnetoelastic memory is proposed using the measured magnetoelastic sensitivity of the material. The results obtained can be used in the development of a method for monitoring the stress-strain state of steel structures during operation under the simultaneous effect of static and dynamic loads.
Influence of the iron additive on the microstructural behavior of an aluminum-copper foundry alloy B206
Authors: Younes R. , Bournane M. , Idir A. , Bouklouche I. , Bradai M. A. , Sadeddine A.
Published: September 2023

Although used and studied since the beginning of the century, the mechanical properties of aluminum-based structural hardening alloys still conceal some secrets that metallurgists are trying to uncover. In this work we are interested in aluminum alloys and more particularly in an Al-Cu alloy. The main objective of this work was to study the influence of structural hardening heat treatments on the evolution of the mechanical and structural properties of B206 alloys. For that, we used several experimental methods adapted to this kind of scientific work. We quote essentially: the thermal treatments of setting in hardening, as well as measurements of the hardness. The analysis of the experimental results obtained by these methods allowed us to explain and to affirm that Al-Cu alloys do not give appreciable structural hardening; because of the difficulty of diffusion of iron and silicon which influences the treatment and brought in a general way to the precipitation of the phase β; plays an important role in the evolution of the mechanical characteristics of Al-Cu alloys.
Mathematical methods in studying temperature-time conditions of the friction surfacing in the manufacture of functionally organized steel-aluminum compositions
Authors: Zaharchenko V. D. , Mikheev R. S. , Kalashnikov I. E.
Published: September 2023

A mathematical model for studying temperature and time conditions of the process of friction surfacing in the manufacture of functionally organized steel-aluminum compositions has been developed and validated. Bars made of pure aluminum grade ER1100 were used as the consumable rod material during friction surfacing. The substrate in the form of a rectangular plate was made of high-quality steel 20. The geometric model of the object when modeling the process of friction surfacing in the ANSYS 2021R2 software package was specified in the form of a rod and a substrate. The initial data for calculating temperature-time conditions of the friction surfacing process are: geometric parameters of the simulation object; characteristics of thermal loads of the heating source which depend on the technological parameters of the surfacing mode (the speed of axial rotation of the rod, axial pressure, boundary conditions of the simulation object for the temperature problem), and auxiliary parameters that determine the order of calculations. The thermal power arising at the point of physical contact between the rotating consumable rod and the substrate was considered a parameter of the source thermal load. The calculation of heat propagation for the friction surfacing process was carried out according to a scheme with a normally circular source located on the substrate surface. The calculation scheme directly reflects the main feature of the friction surfacing process: the introduction of heat due to friction between the rotating consumable rod and the substrate. It is shown that taking into account the boundary conditions and geometric features of the 3D model provide a satisfactory convergence of developed mathematical model and ensure the uncertainty of no more than 5 % in determining the heating temperature of the substrate when forming functional aluminum coatings, as well as composite materials on their base when surfacing them on the surface of steel substrates.
Alteration of pulmonary mitochondrial oxidation status, inflammation, energy metabolizing enzymes, oncogenic and apoptotic markers in mice model of diisononyl phthalate-induced asthma
Authors: Kehinde Samuel Abiodun , Olajide Abosede Temitope , Akinpelu Oyindamola Joy , Ogunsanya Sanmi Tunde
Published: September 2023

Primary plasticizer used in polyvinyl chloride is diisononyl phthalate (DiNP) and exposure to  DiNP has been associated with the development of asthma and allergies. In the current study,  how DiNP alters pulmonary antioxidant status, inflammation, energy metabolizing enzymes,  oncogenic and apoptotic markers in DiNP-induced asthmatic mice was examined. Male  BALB/c mice (n=20, 20-30 g) were divided into 2 groups of 10 mice each: group 1 (control)  received saline (0.2ml/kg) orally for 23 days, and group 2 (DiNP) received 50 mg/kg DiNP  (Intraperitoneal and intranasal) once per day. After the last administration, mice were sacrificed, lungs were removed and used for biochemical and histopathological analysis. DiNP treated mice experienced alterations in their lung histoarchitecture, levels of oncogenic and  apoptotic factors, glycolytic, tricarboxylic acid cycle (TCA), and electron transport chain  enzymes (ETC), antioxidant status, and inflammatory biomarkers. DiNP decreased the  lungs levels of reduced glutathione and ascorbic acid, and the activities of  superoxide dismutase, catalase, and glutathione-s-transferase. In the lungs  of DiNP-treated mice compared to the control group, malondialdehyde and  inflammatory biomarkers (nitric oxide and myeloperoxidase) were significantly  greater (p<0.05). Furthermore, the activities of glycolytic enzymes hexokinase, aldolase,  lactate dehydrogenase were downregulated with a concomitant increase in NADase (77%).  TCA enzymes and ETC enzymes were significantly  reduced as well. CAS-3, p53, Bax, c-MYC, K-Ras increased by 65%, 51%, 70%, 59% and 82%  respectively while BCL-2 decreased by 74%. Histopathological analysis revealed distortion of  the airway structure characterized by inflammatory cell infiltration, oedema, hemorrhage, and  constricted alveoli space. Exposure to DiNP caused oxidative stress which promotes lung  inflammation via depletion of antioxidants, pulmonary energy transduction enzymes, levels of  oncogenic and apoptotic factors were impaired as well, suggesting that the lungs may not be  able to perform its morphological and physiological functions effectively.
Türkiye’de Farklı İklim Kuşakları İçin Yapay Sinir Ağları Kullanılarak Güneş Işınımının Tahmini
Authors: ERTÜRK Sevde , KARA Hakan , AKKUŞ Ceyhun , GENÇ Gamze
Published: September 2023

Güneş enerjisinden gerek termal gerekse elektrik uygulamalarında elde edilen faydalı enerji yüzeye gelen ışınıma bağlıdır ve bu ışınım miktarı konum, zaman, iklimsel koşullar ve çevre koşullarına göre değişmektedir. Güneş enerji destekli enerji sistemlerinin etkin bir şekilde tasarlanması ve çalıştırılması için ışınım miktarının doğru bir şekilde belirlenmesi önem arz etmektedir. Bu çalışmada Türkiye’nin farklı iklim kuşaklarında yer alan dört il (Kayseri, Rize, Hakkari ve İzmir) için MATLAB uygulamasıyla Yapay Sinir Ağları (YSA) modeli oluşturulup güneş ışınımı tahmini yapılmıştır. Güneş ışınımı tahmini yapılırken illerin enlem, boylam ve rakımdan oluşan coğrafik verilerinin etkisinin yanı sıra ortalama sıcaklık, bağıl nem, bulutluluk ve buhar basıncı gibi meteorolojik verilerin etkisi de ele alınmıştır. Tüm bu etkenler göz önüne alındığında kurulan modelde en iyi tahminleme sonucu R2=0.93 değeriyle Hakkari ilinde olup sırasıyla İzmir, Kayseri ve Rize illeri takip etmektedir. Her bir il için YSA ile tahmin edilen değerler ile ölçülen değerler arasında uyum olduğu görülmüştür.
N-Benziletilendiamin Birimi İçeren Yeni Shiff Bazlarının Sentezi, Karakterizasyonu ve İnsan Kolon Kanseri Hücreleri Üzerine Sitotoksik Etkilerinin Belirlenmesi
Authors: HAMURCU Fatma
Published: September 2023

Bu çalışmada N-benziletilendiamin ile 2-Hidroksi-5-metilbenzaldehit, 2-Hidroksi-5-metilasetofenon, 2-Hidroksi-5-kloroasetofenon bileşiklerinin kondenzasyon reaksiyonu sonucu üç yeni Schiff bazı sentezlendi (L1, L2 ve L3). Sentezlenen yeni bileşiklerin yapıları, 1H NMR, 13C NMR, FT-IR ve elemental analiz yöntemleri ile karakterize edildi. Daha sonra, elde edilen bileşiklerin sitotoksik aktiviteleri, insan kolon kanser hücre dizisi (Caco-2, kolon ve HT-29 kolon karsinoma hücre dizisi) kullanılarak araştırıldı. Elde edilen sonuçlar standart kemoterapi ilacı 5-Fluorourasil (5-FU) ile karşılaştırıldı. Sitotoksisite sonuçlarına göre L2 bileşiğinin Caco-2 (kolon) ve HT-29 (kolon) hücre hatlarında en yüksek antikanser aktiviteye sahip olduğu bulundu.
Investigation of the Auxetic of a novel geometric structure and improvement of Poisson’s ratio at different inner thicknesses
Authors: ERDOĞAN İsmail , TOKTAS İhsan
Published: September 2023

Poisson’s ratio, one of the important mechanical properties of materials and structures, is positive for almost all of the known materials and structures. However, auxetic materials or structures has negative Poisson’s ratios. Characteristics of the auxetic structures are very important to be used in design of a new structure. Computational or experimental studies on auxetic structures have been increasing in literature. In this study, a new auxetic lattice structure with different Poisson’s ratios was designed and studied by finite element analysis. Mechanical properties of the newly designed auxetic lattice structures were analyzed with different lattice inner thickness. Results showed that change in inner thickness affects the Poisson’s ratio, mass, volume and surface area of the newly designed Auxetic lattice structures.
EDUKASI DAN SOSIALISASI KESEHATAN, SCREENING, PEMERIKSAAN DAN PENGOBATAN DI KELURAHAN AMASSANGAN KECAMATAN WARA KOTA PALOPO
Authors: Nadirah Andi , Khaddapi Muammar
Published: September 2023

Penyakit kronis merupakan masalah kesehatan yang mengancam masyarakat secara global. Masalah kesehatan ini cenderung berlangsung lama dan merupakan hasil kombinasi faktor genetik, fisiologis, lingkungan, dan perilaku hidup/ pola makan yang berdampak tidak hanya bagi kondisi pasien sendiri tapi juga berdampak bagi keluarga, lingkungan sosial bahkan bagi negara dengan membenahi anggaran biaya kesehatan untuk pengobatan penyakit kronis yang bersifat tahunan. Tujuan dari kegiatan pengabdian pada masyarakat ini adalah meningkatkan pengetahuan dan pola hidup sehat, mendeteksi dini kelompok beresiko dan melakukan pengobatan pada masyarakat penderita penyakit Hipertensi, Diabetes Melitus, cholesterol dan Gout Artritis (asam urat)  atau disebut penyakit tidak menular (PTM) serta penyakit lainnya pada masyarakat di Kelurahan Amassangang. Tahapan kegiatan ini meliputi tahap persiapan, tahap pelaksanaan dan tahap evaluasi atau pelaporan. Kegiatan yang dilakukan berupa edukasi kesehatan, pemeriksaan laboratorium dasar, Sceering dan pengobatan. Hasil dari kegiatan ini diharapkan akan sangat berdampak pada perubahan persepsi dan perilaku kesehatan, pencegahan penyakit kronis, pencegahan komplikasi dari penyakit kronis, penurunan angka morbiditas (kesakitan) dan mortalitas (kematian) akibat penyakit kronis, peningkatan derajat kesehatan masyarakat dan peningkatan kualitas hidup masyarakat.
Role of supervisor as clinical teacher – residents’ perspectives of postgraduate medical institute.
Authors: Mahnaz Raees  , Brekhna Jamil  , Suleman Khan  , Muhammad Shahzad Khan
Published: September 2023

Objective: To determine residents' perceptions of supervisors as clinical teachers. Study Design: Cross-sectional study. Setting: Three Public Sector Teaching Hospitals in Peshawar. Period: August 2019 to May 2020. Material & Methods: For assessing the perceptions of residents in the three public sector teaching hospitals located in Peshawar, a structured questionnaire was used. (N=163) residents were taken as a sample. The response rate was 100% from the three teaching hospitals. For analyzing data SPSS version 22 was used and P < 0.05 was considered as significant. Results: Out of the whole sample (N=163), 63.8 % residents were from medical and allied health specialties, and 36.2 % were from surgical and allied health specialties with Mean ± SD = 1.36 ± 0.836. The findings of this study revealed that the vast majority of trainees were found strongly agreed with the questionnaire responses about their supervisor's role as a clinical teacher. Regarding the supervisor’s role as a clinical teacher, negative perceptions in minority of trainees were found with few problems. Conclusion: In their perceptions of a good clinical teacher, most residents emphasize the teacher’s characteristics. It is important to note that the trainees want to establish a positive relationship with their clinical teacher. Clinically, our residents received high marks from their supervisors.
Impact of fermented lactobacilli acidophilus and antibiotics topically during the phase of re-epithelization in wound repair of rats.
Authors: Hina Khan  , Nadia Naeem  , Sara Sughra  , Sonia Khan  , Shahid Hussain Soomro  , Abdul Sattar Abro
Published: September 2023

Objective: To compare the topical effects of lactobacillus acidophilus strain and topical antibiotics during the phase of re-epithelization in wound repair. Study Design: Experimental Longitudinal study. Setting: Al-Tibri Medical College, Isra University Karachi. Period: June to November 2022. Material & Methods: This longitudinal study took place in in which 45 Wistar rats were acquired and divided into three groups, Group A the control group in which normal saline was applied, Group B in which topical Lactobacillus acidophilus was applied, and Group C in which topical neomycin was applied on the 3rd, 7th, and 14th day of the study. A subcutaneous incision was given on all the rats of equal proportion, and on the 3rd, 7th, and 14th day of sampling a histological section was acquired. A micrometer was used to measure the thickness of the dermis and epidermis. Data was analyzed using SPSS, with the p-value set at <0.05. Results: Significant difference was seen in the mean thickness of epidermis when Lactobacillus acidophilus groups was compared with both Group A and C on the 3rd, 7th, and 14th day of the study. Significant difference was also seen in the mean thickness of the dermis when Lactobacillus acidophilus was compared with both Group A and C on the 3rd, 7th, and 14th day of the study. Conclusion: Lactobacillus acidophilus plays a potent rote in repairing dermal tissue as it increased the thickness of dermis and epidermis.
STUDY ON COMBINING ABILITY IN HYBRID RICE (Oryza sativa L.)
Authors:   Assitant Professor, (Breeding)Tamil Nadu Agricultural University Coimbatore  641 003, K NILAKANTA PILLAI , T.K RAMACHANDRAN ,   Professor and Head, Coconut Research Station, Veppankulam  Thanjavur District
Published: September 2023

Among the lines, ZS 97 A possessed high gca effects for number of productive tillers per plant, number of filled grains per panicle, 100 grain weight, grain yield and straw yield per plant. Among the testers, IR 50 possessed high gea effects for days to panicle emergence, number of productive tillers per plant, number of spikelets per panicle, number of filled grains per panicle, grain yield and straw yield per plant. Among the hybrids in general, ZS 97A/IR 50 expressed high order of expression for the characters viz, total spikelets per panicle, number of filled grains per panicle and grain yield per plant. This high order of expression might be due to the additive genetic effects present in both the parents.
GENETIC VARIABILITY, INTERRELATIONSHIP AND PATH ANALYSIS OF YIELD AND YIELD CHARACTERS IN EARLY MATURING INDICA AND JAPONICA RICE GENOTYPES
Authors:   Professor (Agrl Botany) Tamil Nadu Agricultural University Coimbatore  641 003, A AMIRTHADEVARATHINAM
Published: September 2023

Indicas were characterised by greater values of mean, range and variance components for yield and yield characters. The GCV was the highest for grains per panicle followed by tiller number, culm length and seedling height in both indicas and japonicas. The genetic advance was also high for those characters with high variability. Both additive and non-additive gene actions were important in the expression of characters in both the botanic varieties. Days to 50 per cent flowering, tiller number and panicle length were positively correlated with plant yield in Indicas. In japonicas, days to 50 per cent flowering showed a positive association while tiller number showed a negative association with plant yield. Selection for panicle length would serve as the best criterion for plant yield in both Indicas and japonicas. Path analysis of yield components showed that seedling height and culm length had considerable direct effect in both indioas and japonicas. In addition, tiller number in indicas and days to 50 per cent flowering in japonicas had positive direct effect.
STUDIES ON THE VARIATION OF YIELD IN SORGHUM GENOTYPES
Authors:   University of Agricultural Sciences, Bangalore 560 065, L.B NAIK
Published: September 2023

Three genotypes of Sorghum (CSH 5, CS 3541 and SB 461) were studied with respect to various growth and yield components. There were significant differences among the genotypes with regard to the growth components like LAI and NAR and yield components like 1000 grain weight, grain number per ear, grain weight per ear, grain weight per ear, number of grains por ear and length of the ear. CSH 5 was photosynthetically more efficient during the later stages of crop growth as compared to the other two genotypes. It also recorded higher 1000-grain weight and more grain number per ear than those of CS 3541 and SB 461. About 37 and 23 percent more grain yield was obtained in case of CSH 5 as compared to CS 3541 and SB 461 respectively.
GENETIC VARIABILITY, CORRELATION AND PATH ANALYSIS IN PIGEONPEA
Authors:   National Pules Research Center, Vamban Colony- 622 303,, C NATARAJAN , K THIYAGARAJAN ,   National Pules Research Center, Vamban Colony- 622 303,, A AYYAMPERUMAL ,   National Pules Research Center, Vamban Colony- 622 303,
Published: September 2023

Estimates of variability, heritability, genetic advance, correlation and path analysis were carried out in pigeonpea for seven characters. The highest genotypic coefficient of variation was observed for pod number followed by cluster number and seed yield while it was lowest for seeds per pod. High heritability and genetic advance were observed for pod number, cluster number and seed yield. Pod number, cluster number and plant height were positively and significantly correlated with seed yield. Cluster number showed high positive direct effect on seed yield. The studies suggested that selection for clusters per plant, pods per plant and plant height is important to evolve high yielding varieties of pigeonpea.
COMBINING ABILITY AND HETEROSIS IN GOSSYPIUM BARBADENSE
Authors:   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, D KRISHNADOSS , V MYLSWAMI ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, G NALLATHAMBI ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, M KADAMBAVANASUNDARAM ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003
Published: September 2023

A four parent full diallel analysis was made in Gossyplum barbadense cotton to study the nature of general and specific combining abilities and the magnitude of relative heterosis for yield of seed cotton, halo length and ginning outturn. Yield of seed cotton was predominantly under the control of dominance gene action where as halo length and ginning were predominantly under the control of additive gene action. TCB 295 was the best combiner for halo length and TCB 296 was the best combiner for ginning outturn. Heterosis for seed cotton yield ranged from 18.11% to 90.64% while the magnitude of heterosis was low in respect of halo length and ginning. The hybrid combination TCB 293 x TCB 296 was suggested for exploiting through heterosis breeding for increasing the seed cotton yield.
HETEROSIS IN THE INTRA AND INTER SUB-SPECIFIC CROSSES OF GROUNDNUT (ARACHIS HYPOGAEA L.)
Authors:   Regional Research Station, Vridhachalam 606 001., V MANOHARAN , P VINDHIYAVARMAN ,   Regional Research Station, Vridhachalam 606 001., R SETHUPATHI RAMALINGAM ,   Regional Research Station, Vridhachalam 606 001., M.R SIVARAM ,   Regional Research Station, Vridhachalam 606 001.
Published: September 2023

The Inter-subspecific crosses involving Spanish x Virginia genotypes exhibited greater magnitude of heterobeltiosis for pod yield, pod number, pod and kernel weights than the intra- subspecific crosses. The intra-subspecific crosses were superior for plant height. Negative heterosis was observed for shelling percentage in both the types of crosses.
GENETICS OF RUST (PUCCINIA ARACHIDIS SPEG.) IN GROUNDNUT
Authors:   Regional Research Station, Vridhachalam 606 001., P VINDHIYAVARMAN , R RATHINASAMY ,   Regional Research Station, Vridhachalam 606 001., M MUTHUSAMY ,   Regional Research Station, Vridhachalam 606 001.
Published: September 2023

Rust (Puccinia arachidis Speg.) resistant groundnut genotype NC Ac 17090 was crossed with susceptible genotype VG5 and their segregating populations of F1, F2 and B; and B2 were studied for the reaction to the disease. The additive component (d) was significant, while the dominance (h) was not significant. The epistatic interactions, additive x dominance () and dominance x dominance (1) were not significant.
GENETIC VARIABILITY IN SESAMUM
Authors:   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, M KANDASWAMI , M KADAMBAVANA SUNDARAM ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, C.S SRIDHARAN ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, S.R SREE RANGASWAMY ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003
Published: September 2023

Variability, heritability, genetic advance, phenotypic correlation, geno- typic correlation, environmental correlation and coheritability were estimated in 28 varieties of sesame (Sesamum indicum L.). High heritability with high genetic advance was observed in yield per plant, high heritability and low genetic advance in 50% flowering, and low heritability and low genetic advance in number of capsules on main stem, number of capsules on branches and total number of capsules per plant. Positive and significant phenotypic, genotypic and environmental correlations were observed between number of capsule on main stem and total number of capsule per plant. Coheritability estimates of positive and high magnitude were observed between yield and 50% flowering and plant height and 50% flowering. High and negative coheritability estimates was observed between 50% flowering and number of branches.
VARIABILITY, HERITABILITY AND GENETIC ADVANCE IN SESAME (SESAMUM INDICUM L.)
Authors:   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003, O UMESH KUMAR REDDY , M STEPHEN DORAIRAJ ,   School of Genectics, Tamil Nadu Agricultural University Coimbatore  641 003
Published: September 2023

Genotypic coefficient of variation, heritability and genetic advance were assessed in 50 genotypes of Sesame (Sesamum indicum L.). The differences between the genotypes were highly significant for all the 15 characters studied. Among the characters, number of capsules per branch had high heritability combined with high genetic advance while seed number per capsule, DMP and first capsule bearing node had high heritability with medium genetic advance. These traits are the most suitable for improvement through selection
CORRELATION BETWEEN YIELD AND YIELD COMPONENTS IN SUNFLOWER
Authors:   Regional Research Station Kovilangulam 626 107, S CHIDAMBARAM , N SUNDARESAN ,   Regional Research Station Kovilangulam 626 107
Published: September 2023

Correlation between seed yield and other characters in 15 parents and 36 hybrids of sunflower revealed that plant height, head diameter and 100 seed weight had highly significant and positive correlation with seed yield. Among them, the plant height and head diameter had significant and positive intercorrelation among themselves. A significant and positive intercorrelation was noticed between harvest index and oil content which indicated the importance of harvest index for improving the oil content on sunflower.
STUDIES ON COMBINING ABILITY IN SUNFLOWER (HELIANTHUS ANNUUS. L)
Authors:   Regional Research Station Kovilangulam 626 107, S CHIDAMBARAM , N SUNDARESAN
Published: September 2023

Combining ability studies in sunflower revealed that additive gene action was predominant for all the characters except 100 seed weight and oil content. Among the female parents, EC 85820 and EC 69874 were the best general combiners for earliness, K 74 for seed yield and EC 93617 for oil content. The tester parents K 1 and Co 1 were the best general combiners for seed yield and oil content respectively. The best cross combinations for seed yield were EC 75272 x K 2 and Kanpur Selection x Co 1, while for oil content it was EC 93617 x Co 1. In general there was no correspondence between mean performance and sca effects of the crosses.
HETEROSIS IN SORGHUM UNDER DIFFERENT ENVIRONMENTS
Authors:   Professor and Head, Cotton Research station,Srivalliputhur 626 125 Tamil Nadu., N MOHAMED SHERIFF , M.N PRASAD ,   Professor (Genectics) TNAU, Coimbatore
Published: September 2023

Six parents in sorghum viz, Co18, 148, Co 23, Co 22, CSV. 3 and As. 3880 were crossed in all possible combinations and the hybrids along with the parents were studied for three economic traits under four different environments consisting two seasons and two manurial levels. For panicle length, number of grains/panicle and grain yield/panicle, heterosis was observed in most of the crosses. Among the parents Co 23 showed high mean expression for number of grains and grain yield. Further the hybrids involving Co 23 as one of the parents revealed high per se performance and heterosis for grain yield.
GENETIC VARIABILITY IN KODO MILLET (PASPALUM SCROBICULATUM L.)
Authors:   Tamil Nadu Agricultural University Coimbatore  641 003, G KANDASAMY , N RAMAMOORTHY ,   Tamil Nadu Agricultural University Coimbatore  641 003 Tamil Nadu Agricultural University Coimbatore  641 003, V MANOHARAN ,   Tamil Nadu Agricultural University Coimbatore  641 003
Published: September 2023

Fifty genotypes of Kodo millet were used to study the genetic variability among them for six economic attributes. The genotypic coefficient of variation was high for straw yield. Plant height, 1000-grains weight and straw yield exhibited higher heritability estimates. Straw yield also recorded the highest genetic advance indicating that it is controlled by additive gene action and that phenotypic selection for its improvement will be effective.