bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Spectral Characteristics of Cotton Leaves at Bud Stage under Different Nitrogen Application Rates
Authors: Wang Jiaqiang , Yin Caiyun , Liu Weiyang , Xia Wenhao , Ning Songrui
Published: March 2024

Soil salinity affects nutrient uptake by cotton. The cotton bud stage is a very important period in the process of cotton planting and directly affects the yield of cotton. The nutritional status of the bud stage directly affects the reflectance spectra of cotton canopy leaves. Therefore, it is of great significance to nondestructively monitor the nutritional status of the cotton bud stage on salinized soil via spectroscopic techniques and perform corresponding management measures to improve cotton yield. In this study, potted plants with different nitrogen application rates were set up to obtain the reflection spectral curves of cotton bud stage leaves, analyze their spectral characteristics under different nitrogen application rates, and establish spectral estimation models of chlorophyll density. The results are as follows: in the continuum removal spectrum of the cotton bud stage, the lowest point of the absorption valley near 500 nm shifted to the shortwave direction with an increasing nitrogen application rate. The mean reflectance between 765 and 880 nm was significantly different between nitrogen-stressed and nitrogen-unstressed cotton. The average reflectance of the near-infrared band, the absorption valley depths near 500 nm and 675 nm, the first derivative of the 710 nm reflectance, and the second derivatives of the 690 nm and 730 nm reflectance increased with increasing nitrogen application and chlorophyll density, and significant correlations were observed with the chlorophyll density. These parameters were modeled using support vector regression (SVR) and artificial neural network (ANN) methods, two commonly used algorithms in the field of machine learning. The determination coefficients of the three chlorophyll samples via the ANN models were 0.92, 0.77, and 0.94 for the modeling set and 0.77, 0.69, and 0.77 for the verification set. The ratio of quartile to root-mean-square error (RPIQ) of the ANN model was greater than 2.2, and the ratio of the standard error of the measured value to the standard error of the predicted (SEL/SEP) was close to 1, indicating that the chlorophyll density estimation models built based on the ANN algorithm had robust prediction ability. Our model could accurately estimate the leaf chlorophyll density in the cotton bud stage.
Rhizosphere-Associated Microbiota Strengthen the Pathogenicity of Meloidogyne incognita on Arabidopsis thaliana
Authors: Zhou Xing-Kui , Ma Li , Yang Zi-Xiang , Bao Ling-Feng , Mo Ming-He
Published: March 2024

Microorganisms associated with nematodes or enriched in galls have been reported previously to aid plant-parasitic nematodes (PPNs) in infecting and establishing parasitism in the host plants. However, the rhizosphere-associated microbiota, which strengthens the pathogenicity of PPNs, remains largely unknown. This study illustrated rhizosphere bacteria enhancing Meloidogyne incognita infection on Arabidopsis thaliana by comparing the gall numbers of the treatments between natural soil and the sterile soil or soils drenched with antibiotics. By culture-dependent and pot testing methods, sixteen bacterial combinations from rhizosphere soils of A. thaliana were demonstrated to enhance M. incognita pathogenicity, including the most effective Nocardioides. Single-strain inoculation from the Nocardioides combination significantly resulted in M. incognita forming more galls on roots than the control, in which N. nematodiphilus R-N-C8 was the most effective strain. Strain R-N-C8 could substantially facilitate the M. incognita second-stage juveniles (J2s) moving towards the roots of A. thaliana and infecting the roots by releasing chemoattractant to attract J2s. The chemoattractant from strain R-N-C8 was determined to be L-lysine. This study furnishes vital insights for understanding the infection of root-knot nematodes associated with rhizosphere microbes.
Impact of Three Entomopathogenic Fungal Isolates on the Growth of Tomato Plants—Ectoapplication to Explore Their Effect on Tetranychus urticae
Authors: Wakil Waqas , Boukouvala Maria C. , Kavallieratos Nickolas G. , Naeem Aqsa , Ghazanfar Muhammad Usman , Alhewairini Saleh S.
Published: March 2024

Tetranychus urticae is an important pest of tomato crops globally, affecting plant yield and growth. Beauveria bassiana and Metarhizium robertsii have the potential to control T. urticae. We investigated the influence of two B. bassiana (i.e., WG-12 and WG-19) isolates and one M. robertsii (WG-02) isolate when colonizing different plant organs (leaves, stems, and roots) and their influence on the growth of tomato plants, through foliar, root-dipping, and seed-soaking application techniques. We also examined the acaricidal activity of the three isolates against T. urticae (female adults), spraying tomato leaf discs with each isolate separately. After 28 days, WG-12 and WG-19 colonized 97 and 91% of the leaves after foliar inoculation, whereas WG-02 exhibited the lowest leaf colonization (76%). The height of the tomato plants, the root length, the number of leaves, and the weight of the biomass above and below the ground were enhanced significantly after inoculation with WG-02 vs. B. bassiana isolates and control. The complete mortality of T. urticae was caused by WG-12 and WG-02 after 10 days, whereas WG-19 killed 94% of the adults. For the effective management of T. urticae, we propose the application of the WG-02 isolate since it provides complete protection and promotes the growth of tomato plants.
Bacteriophage Therapy in Companion and Farm Animals
Authors: Bianchessi Laura , De Bernardi Giulia , Vigorelli Martina , Dall’Ara Paola , Turin Lauretta
Published: March 2024

Bacteriophages, which are viruses with restricted tropism for bacteria, have been employed for over a century as antimicrobial agents; they have been largely abandoned in Western countries but are constantly used in Eastern European countries with the advent of antibiotics. In recent decades, the growing spread of multidrug-resistant bacteria, which pose a serious threat to worldwide public health, imposed an urgent demand for alternative therapeutic approaches to antibiotics in animal and human fields. Based on this requirement, numerous studies have been published on developing and testing bacteriophage-based therapy. Overall, the literature largely supports the potential of this perspective but also highlights the need for additional research as the current standards are inadequate to receive approval from regulatory authorities. This review aims to update and critically revise the current knowledge on the application of bacteriophages to treat bacterial-derived infectious diseases in animals in order to provide topical perspectives and innovative advances.
The Importance of Carbapenemase-Producing Enterobacterales in African Countries: Evolution and Current Burden
Authors: Chelaru Edgar-Costin , Muntean Andrei-Alexandru , Hogea Mihai-Octav , Muntean Mădălina-Maria , Popa Mircea-Ioan , Popa Gabriela-Loredana
Published: March 2024

Antimicrobial resistance (AMR) is a worldwide healthcare problem. Multidrug-resistant organisms (MDROs) can spread quickly owing to their resistance mechanisms. Although colonized individuals are crucial for MDRO dissemination, colonizing microbes can lead to symptomatic infections in carriers. Carbapenemase-producing Enterobacterales (CPE) are among the most important MDROs involved in colonizations and infections with severe outcomes. This review aimed to track down the first reports of CPE in Africa, describe their dissemination throughout African countries and summarize the current status of CRE and CPE data, highlighting current knowledge and limitations of reported data. Two database queries were undertaken using Medical Subject Headings (MeSH), employing relevant keywords to identify articles that had as their topics beta-lactamases, carbapenemases and carbapenem resistance pertaining to Africa or African regions and countries. The first information on CPE could be traced back to the mid-2000s, but data for many African countries were established after 2015–2018. Information is presented chronologically for each country. Although no clear conclusions could be drawn for some countries, it was observed that CPE infections and colonizations are present in most African countries and that carbapenem-resistance levels are rising. The most common CPE involved are Klebsiella pneumoniae and Escherichia coli, and the most prevalent carbapenemases are NDM-type and OXA-48-type enzymes. Prophylactic measures, such as screening, are required to combat this phenomenon.
Active Tunable Elastic Metasurface for Abnormal Flexural Wave Transmission
Authors: Lin Bizun , Li Jingru , Lin Wei , Ma Qingfen
Published: March 2024

An active elastic metasurface has more flexibility than a passively modulated elastic metasurface, owing to the manipulation of the phase gradient that can be realized without changing the geometrical configuration. In this study, a negative proportional feedback control system was employed to provide positive active control stiffness for adaptive unit cells, with the aim of achieving the active modulation of the phase gradient. The relationship between the control gain and the phase velocity of the flexural wave was derived, and the transfer coefficients and phase shifts of the flexural wave through the adaptive unit cells were resolved using the transfer matrix method. Finite element simulations for wave propagations in the adaptive unit cells were conducted, and they verified the analytic solutions. Based on this theoretical and numerical work, we designed active elastic metasurfaces with adaptive unit cells with sub-wavelength thicknesses according to the generalized Snell’s law. These metasurfaces show flexibility in achieving abnormal functions for transmitted waves, including negative refraction and wave focusing, and transforming guided waves at different operating frequencies by manipulating the control gain. Therefore, the proposed active metasurface has great potential in the fields of the tunable manipulation of elastic waves and the design of smart devices.
Influence of Isometric and Dynamic Fatiguing Protocols on Dynamic Strength Index
Authors: Smajla Darjan , Šarabon Nejc , García Ramos Amador , Janicijevic Danica , Kozinc Žiga
Published: March 2024

Background: Strength and conditioning experts widely recognize the dynamic strength index (DSI) as a tool for assessing an athlete’s ability to utilize strength in dynamic actions. The DSI is calculated as the ratio of peak force in dynamic actions versus isometric ones. To date, the influence of fatigue on the DSI is still not fully understood. This study aimed to explore the effects of both dynamic and isometric fatigue tasks on the DSI. Methods: A total of 24 physically active participants underwent fatigue tests involving repeated countermovement jumps (dynamic) and repeated isometric mid-thigh pulls (isometric) in separate visits. Results: The results revealed a marked drop in performance, with dynamic force showing a more significant reduction (p < 0.001; d = 1.57) than isometric force (p = 0.015; d = 0.30). After the isometric fatigue task, the DSI increased, indicating a more substantial decline in isometric force (p < 0.001; d = 1.75) compared to dynamic force (p = 0.313; d = 0.08). Following this trend, the DSI decreased post-dynamic fatigue (p < 0.001; d = 0.99) and increased post-isometric fatigue (p < 0.001; d = 3.11). Conclusion: This research underscores the need to consider fatigue’s task-specific effects on the DSI, enabling more tailored training methodologies for athletes.
Impact of Customized Content in 3D Virtual Reality Motionless Imagery Exercise through Avatar on Emotional Well-Being, Cognition, and Physiological Response
Authors: Lee Myungchul , Kim Donghyun , Lee Myungho , Han Kyunghun
Published: March 2024

People in situations where physical activity is difficult face limitations in participating in exercise to maintain health. Participation in exercise is especially difficult when social non-face-to-face situations such as infectious diseases occur. This causes various social problems. Background: The study developed a 3D virtual reality (VR) Motionless Imagery Exercise through Avatar (MIEA), provided customized content such as companion avatars, and aimed to verify its effects. Methods: This study was conducted using a randomized block design experiment. The participants were 40 healthy adults (20 experiment and 20 control group) aged between 19 and 49 years. Both groups engaged in interventions three times per week for 20 min over six weeks. Data obtained from measurements of emotional well-being, cognition, and physiological responses before and after the experiment were analyzed. Results: The experimental group showed significant improvements in emotional well-being compared to the control group, particularly in trait anxiety, resilience, stress, and positive affect. The similar physiological responses observed in the experimental group resembled exercise-induced responses. Verbal memory and working memory in the experimental group improved more in the experimental group than the control group. Conclusions: The results showed the effectiveness of a 3D VR MIEA, indicating its positive impact on exercise outcomes. Furthermore, the provision of customized content including companion avatars was validated to enhance emotional well-being. This suggests that incorporating content-driven companion avatars in developing virtual reality exercise programs can evoke emotional effects.
Active Ankle–Foot Orthosis Design and Computer Simulation with Multi-Objective Parameter Optimization
Authors: Lara-Velazquez Carlos Armando , Ramirez-Paredes Juan-Pablo , González-Sandoval Beatriz Verónica
Published: March 2024

There are many current active orthosis designs to assist with disabilities related to foot-drop, with most of them intervening during the whole gait cycle. We propose that, for the treatment of foot-drop, it is possible to design an ankle–foot device that will assist a walking user only during the dorsiflexion stages of the gait, avoiding interference with other stages, by using a single actuator with a simple transmission and a suspension block. This design can be improved by the use of multi-objective optimization to obtain a static set of parameters that are applicable to varying initial conditions. We present a computer simulation study of an active ankle–foot orthosis design, based on the interaction of a cam and lever with a suspension block, with the objective of assisting only with dorsiflexion during the gait cycle, leaving the rest of the movements unimpeded while reducing the complexity and weight of the device. This design is validated using a full simulation environment that includes the movements of the lower leg and foot, as they interact with our device and a ground element. As part of the design and validation, we found sets of mechanical and control parameters that provoke adequate output behavior of the orthosis to help the wearer perform a moderate-speed, normal gait. To optimize the design, we proposed three objectives to warrant ankle angle accuracy, minimal oscillations, and low energy consumption. A set of solutions was obtained with multi-objective optimization algorithms NSGA-II and RVEA to tune the parameters of the active orthosis. The solutions set from RVEA resulted in lower mean and standard deviation values for the oscillations and energy objectives in comparison to the solutions from NSGA-II, while for the MSE objective, NSGA-II obtained lower mean and standard deviation; for the energy consumption objective, the mean score using RVEA is 17% less than with NSGA-II. The orthosis is shown to be robust to differences in initial ankle angles. We observed that it is possible to obtain a broad set of solutions with a good performance during the gait cycle in controlled spaces and that in this application, the RVEA algorithm results in a better option for optimization to balance the objectives.
DiffRS-net: A Novel Framework for Classifying Breast Cancer Subtypes on Multi-Omics Data
Authors: Zeng Pingfan , Huang Cuiyu , Huang Yiran
Published: March 2024

The precise classification of breast cancer subtypes is crucial for clinical diagnosis and treatment, yet early symptoms are often subtle. The use of multi-omics data from high-throughput sequencing can improve the classification accuracy. However, most research primarily focuses on the association between individual omics data and breast cancer, neglecting the interactions between different omics. This may fail to provide a comprehensive understanding of the biological processes of breast cancer. Here, we propose a novel framework called DiffRS-net for classifying breast cancer subtypes by identifying the association among different omics. DiffRS-net performs a differential analysis on each omics datum to identify differentially expressed genes (DE-genes) and adopts a robustness-aware Sparse Multi-View Canonical Correlation Analysis to detect multi-way association among DE-genes. These DE-genes with high levels of correlation are then used to train an attention learning network, thereby enhancing the prediction accuracy of breast cancer subtypes. The experimental results show that, by mining the associations between multi-omics data, DiffRS-net achieves a more accurate classification of breast cancer subtypes than the existing methods.
Effects of Feeding Recycled Food Waste-Based Diets on Gut Health, Nutrient Digestibility, and Bone Quality in Laying Hens
Authors: Dao Hiep Thi , Sharma Nishchal K. , Kim Eunjoo , Barekatain Reza , Swick Robert A. , Moss Amy F.
Published: March 2024

This study explored feeding recycled food waste-based diets for gut health, nutrient digestibility, bone morphology, and bone mineral level in laying hens. Hy-Line Brown laying hens (n = 150) were randomly allocated to three experimental treatments consisting of a commercial control diet, a recycled food waste-based diet, and a 50:50 blend of the control and food waste-based diets, with 50 replicates of a single bird per cage per treatment from 24 to 63 weeks of age. Egg production was recorded daily and feed intake was measured weekly. The gut pH, jejunal and ileal morphology, nutrient digestibility, bone morphology, and mineral composition were measured at 63 weeks of age. Hens on the food waste-based treatment had similar egg production but lower feed conversion ratio (FCR, 1.948 vs. 2.172 kg feed/kg egg, p < 0.001) and higher ileal pH (p < 0.001) and bone ash content (p < 0.001) compared to birds on the control treatment. Moreover, hens fed the food waste-based diets had higher ileal digestible energy (p < 0.001); ileal energy digestibility (p < 0.01); tibia S, Fe, Mn, and Zn levels (p < 0.05); and Mg, K, S, Mn, and Mo digestibility (p < 0.05) compared to hens fed the control diets. Hens offered the 50:50 blend diets had higher tibia P, Mg, and Mo levels (p < 0.05) and higher Ca digestibility (p < 0.05) compared to those fed the control diets. Thus, feeding recycled food waste-based diets is effective to improve laying performance, nutrient digestibility, and bone mineralization in laying hens.
Interpretability in Sentiment Analysis: A Self-Supervised Approach to Sentiment Cue Extraction
Authors: Sun Yawei , He Saike , Han Xu , Luo Yan
Published: March 2024

In this paper, we present a novel self-supervised framework for Sentiment Cue Extraction (SCE) aimed at enhancing the interpretability of text sentiment analysis models. Our approach leverages self-supervised learning to identify and highlight key textual elements that significantly influence sentiment classification decisions. Central to our framework is the development of an innovative Mask Sequence Interpretation Score (MSIS), a bespoke metric designed to assess the relevance and coherence of identified sentiment cues within binary text classification tasks. By employing Monte Carlo Sampling techniques optimized for computational efficiency, our framework demonstrates exceptional effectiveness in processing large-scale text data across diverse datasets, including English and Chinese, thus proving its versatility and scalability. The effectiveness of our approach is validated through extensive experiments on several benchmark datasets, including SST-2, IMDb, Yelp, and ChnSentiCorp. The results indicate a substantial improvement in the interpretability of the sentiment analysis models without compromising their predictive accuracy. Furthermore, our method stands out for its global interpretability, offering an efficient solution for analyzing new data compared to traditional techniques focused on local explanations.
Effect of Sugarcane Bagasse, Softwood, and Cellulose on the Mechanical, Thermal, and Morphological Properties of PP/PE Blend
Authors: Mohomane Samson M. , Motaung Tshwafo E.
Published: March 2024

The usage of cellulosic fibers as fillers for thermoplastics has generated great interest due to their numerous advantages and benefits compared to conventional fibers. This article examines a comparative study on the mechanical, thermal, and morphological properties of polypropylene/polyethylene (PP/PE)/cellulose (sugarcane bagasse (SCB) and softwood (SW)) blend composites prepared through melt compounding. The morphology of the obtained PP/PE/SCB and PP/PE/SW blend composites was investigated using scanning electron microscopy (SEM). The X-ray diffraction (XRD) analysis showed reduced crystallinity of the PP/PE blend after fiber interaction. Thermal results showed that the PP/PE/SW blend was more thermally stable compared to the PP/PE/SCB blend. Additionally, the onset temperature of main degradation decreased with th e incorporation of extracted celluloses. Differential scanning calorimetry (DSC) analysis revealed that the introduction of SCB or SW raw fiber and extracted celluloses did not significantly change the melting and crystallization behavior of the PP/PE blend. Dynamic mechanical analysis (DMA) revealed that the storage modulus of the PP/PE/SCB raw and PP/PE/SW raw materials were lower than their corresponding cellulose blend composites across the temperature range studied.
Formation of Conductive Networks in Polysulfone Filled with Graphite-Derived Materials
Authors: Mohammad Hussam , Stepashkin Andrey A. , Tcherdyntsev Victor V.
Published: March 2024

Composites based on polysulfone materials filled with various types of graphite and carbon black were studied and a solution technique was used to create composite materials with filling degrees ranging from 30 to 70% by weight. High filling levels with graphite fillers enabled thermal conductivity of 17.4 W/m·K to be achieved. The addition of carbon black as a filler to the composite helped to improve its mechanical characteristics, and its influence on electrical and thermal conductivity has also been explored. Natural graphite provides the best effect on composite thermal and electrical properties, whereas using artificial graphite allows to improve the mechanical behavior of composites. The relationship between sample density, porosity, and composition, as well as the effect of these factors on composite conductivity, has been studied and addressed.
Posterior Semicircular Canal Dehiscence with Vestibulo-Ocular Reflex Reduction for the Affected Canal at the Video-Head Impulse Test: Considerations to Pathomechanisms
Authors: Castellucci Andrea , Dumas Georges , Abuzaid Sawsan M. , Armato Enrico , Martellucci Salvatore , Malara Pasquale , Alfarghal Mohamad , Ruberto Rosanna Rita , Brizzi Pasquale , Ghidini Angelo , Comacchio Francesco , Schmerber Sébastien
Published: March 2024

Posterior semicircular canal dehiscence (PSCD) has been demonstrated to result in a third mobile window mechanism (TMWM) in the inner ear similar to superior semicircular canal dehiscence (SSCD). Typical clinical and instrumental features of TMWM, including low-frequency conductive hearing loss (CHL), autophony, pulsatile tinnitus, sound/pressure-induced vertigo and enhanced vestibular-evoked myogenic potentials, have been widely described in cases with PSCD. Nevertheless, video-head impulse test (vHIT) results have been poorly investigated. Here, we present six patients with PSCD presenting with a clinical scenario consistent with a TMWM and an impaired vestibulo-ocular reflex (VOR) for the affected canal on vHIT. In two cases, an additional dehiscence between the facial nerve and the horizontal semicircular canal (HSC) was detected, leading to a concurrent VOR impairment for the HSC. While in SSCD, a VOR gain reduction could be ascribed to a spontaneous “auto-plugging” process due to a dural prolapse into the canal, the same pathomechanism is difficult to conceive in PSCD due to a different anatomical position, making a dural herniation less likely. Alternative putative pathomechanisms are discussed, including an endolymphatic flow dissipation during head impulses as already hypothesized in SSCD. The association of symptoms/signs consistent with TMWM and a reduced VOR gain for the posterior canal might address the diagnosis toward PSCD.
Assessment of Human Health Impacts from Invasive Pufferfish (Attacks, Poisonings and Fatalities) across the Eastern Mediterranean
Authors: Ulman Aylin , Abd Rabou Abdel Fattah Nazmi , Al Mabruk Sara , Bariche Michel , Bilecenoğlu Murat , Demirel Nazli , Galil Bella S. , Hüseyinoğlu Mehmet Fatih , Jimenez Carlos , Hadjioannou Louis , Kosker Ali Rıza , Peristeraki Panagiota , Saad Adib , Samaha Ziad , Stoumboudi Maria Th. , Temraz Tarek A. , Karachle Paraskevi K.
Published: March 2024

The silver-cheeked toadfish Lagocephalus sceleratus (Gmelin 1789), and to a lesser degree the orange spotted toadfish Torquigener hypselogeneion (Bleeker, 1852), pose threats to human health from physical attacks and poisonings in the Eastern Mediterranean Sea. This study reviewed human health-related impacts resulting from these pufferfish, compiling and assessing records from online sources, the peer-reviewed literature, medical records, personal interviews, and observations across the Eastern Mediterranean in the years 2004 to 2023. A total of 198 events impacting human health were documented: 28 records of physical attacks, at least 144 non-lethal poisoning episodes, and 27 human fatalities resulting from consumption. The majority of the reported incidences occurred in Syria, Türkiye, and Lebanon. Most physical attacks occurred in summer, while most poisoning events occurred during winter. The number of recorded incidents greatly increased after 2019, especially with regard to poisonings, yet whether this is related to greater media attention, or to increased fish abundance is unclear. This is the first comprehensive study to collate findings on attacks, poisonings and fatalities caused by these pufferfish in the Mediterranean Sea, and may help in improving national health policies. We urge the continuation of national campaigns to caution residents and tourists of these species’ high toxicities and potential aggressiveness.
Involvement of Glucosamine 6 Phosphate Isomerase 2 (GNPDA2) Overproduction in β-Amyloid- and Tau P301L-Driven Pathomechanisms
Authors: Lachén-Montes Mercedes , Cartas-Cejudo Paz , Cortés Adriana , Anaya-Cubero Elena , Peral Erika , Ausín Karina , Díaz-Peña Ramón , Fernández-Irigoyen Joaquín , Santamaría Enrique
Published: March 2024

Alzheimer’s disease (AD) is a neurodegenerative olfactory disorder affecting millions of people worldwide. Alterations in the hexosamine- or glucose-related pathways have been described through AD progression. Specifically, an alteration in glucosamine 6 phosphate isomerase 2 (GNPDA2) protein levels has been observed in olfactory areas of AD subjects. However, the biological role of GNPDA2 in neurodegeneration remains unknown. Using mass spectrometry, multiple GNPDA2 interactors were identified in human nasal epithelial cells (NECs) mainly involved in intraciliary transport. Moreover, GNPDA2 overexpression induced an increment in NEC proliferation rates, accompanied by transcriptomic alterations in Type II interferon signaling or cellular stress responses. In contrast, the presence of beta-amyloid or mutated Tau-P301L in GNPDA2-overexpressing NECs induced a slowdown in the proliferative capacity in parallel with a disruption in protein processing. The proteomic characterization of Tau-P301L transgenic zebrafish embryos demonstrated that GNPDA2 overexpression interfered with collagen biosynthesis and RNA/protein processing, without inducing additional changes in axonal outgrowth defects or neuronal cell death. In humans, a significant increase in serum GNPDA2 levels was observed across multiple neurological proteinopathies (AD, Lewy body dementia, progressive supranuclear palsy, mixed dementia and amyotrophic lateral sclerosis) (n = 215). These data shed new light on GNPDA2-dependent mechanisms associated with the neurodegenerative process beyond the hexosamine route.
The Relationship between Live Sports Learning and Exercise Behavior in College Students: A Serial Mediation Model
Authors: Guo Tiantian , Liu Liping , Yang Yuqing , Shang Yao , Chen Shan-Ping
Published: March 2024

Physical exercise is crucial to the development of students’ physical and mental health. This study explored the relationship between live sports learning and college students’ exercise behaviors, and the mediating roles of exercise motivation and exercise commitment, aiming to provide theoretical bases for the future that explain the mechanism of live sports learning in exercise behaviors, as well as practical guidance for the promotion of positive physical exercise behaviors in college students. In total, 1189 college students from China volunteered to complete questionnaires. The results showed that live sports learning positively predicted college students’ exercise behavior and that live sports learning was able to affect exercise behavior through the mediating roles of exercise motivation and exercise commitment, with specific mediating paths including the two independent mediating paths and a serial mediating path of exercise motivation and exercise commitment. This study confirmed, for the first time, on live sports learning in the process of promoting exercise behavior. It is suggested that educators instruct college students to regulate their participation in live sports learning and to cultivate healthy exercise motivation and exercise commitment, which is an effective way to facilitate college students’ practice of physical activity.
Reducing Employees’ Time Theft through Leader’s Developmental Feedback: The Serial Multiple Mediating Effects of Perceived Insider Status and Work Passion
Authors: Wang Zhen , Wang Qing , Wang Daojuan
Published: March 2024

Time theft, especially with the shift to remote work during the pandemic, is an increasing challenge for organizations. Existing studies demonstrate that both authoritarian leadership and laissez-faire leadership can exacerbate time theft, putting leaders in a behavioral dilemma of neither being strict nor lenient. Additionally, the pervasive and covert nature of time theft diminishes the effectiveness of subsequent corrective actions. Our study aims to investigate how to prevent time theft by mitigating employees’ inclinations. Based on role theory, our study examines whether supervisor developmental feedback can encourage employees to perform work roles more appropriately. To uncover the complicated internalization process of role expectation, our study incorporates perceived insider status and work passion as serial mediators and considers the boundary effect of leaders’ word–deed consistency. In Study 1, a survey of 402 employees revealed that supervisor developmental feedback can negatively predict employee time theft through employees’ perceived insider status and work passion. Study 2 employs the same sample to further identify three topics of supervisor developmental feedback: skill learning, attitude learning, and social learning. Moreover, serial multiple mediating effects are affirmed across topics. The findings suggest that providing feedback on employees’ learning and growth is an effective approach to prevent time theft.
Multi-Objective Optimization of Tasks Scheduling Problem for Overlapping Multiple Tower Cranes
Authors: Wang Yanyan , Zhao Wenjie , Cui Wenjing , Zhou Guangqiang
Published: March 2024

The scheduling of tower crane operations is a complex process. Overlapping areas between tower cranes often lead to increased collision possibilities, resulting in additional tower crane operation complexity. Single objectives related to time or economic aspects were always considered in dealing with this issue, which neglected other objectives and the relationships between different objectives. Therefore, this article proposes a novel method for the schedule of prefabricated component lifting tasks on the construction site, integrating the multi-objective optimization model with the decision-making method with the aim of minimizing energy consumption costs and minimizing the amplitude of the costs among multiple tower cranes. A non-dominated sorting genetic algorithm-III (NSGA-III) written in Python is used as the multi-objective optimization algorithm—which considers the selection of tasks for each tower crane and the order of lifting for each tower crane and technique for order preference by similarity to an ideal solution (TOPSIS), and is applied as the decision-making method for ranking the Pareto front. Then, a green construction production and education integration training building construction project located in Jinan, China is used as the case study to verify that the method is practical and reasonable. The results show that conflicts can be effectively avoided, energy consumption costs reduced, and equipment utilization increased by rationally distributing lifting tasks among multiple overlapping tower cranes. And among the top 11 solutions, the lifting tasks and priorities for tower crane 1 are close to the same. In contrast, the task lifting for tower crane 2 was assigned based on the balance of the energy consumption costs of the two tower cranes. The discovery of this article is helpful to eliminate collisions, interference, and frequent start and stop of several tower cranes, so as to realize the safe, stable, and efficient operation of the construction site.
The Evaluation National Green Building Index Based on a Survey of Personnel Satisfaction: The Case of Hubei Province, China
Authors: Ouyang Shengda , Shan Xiaofang , Deng Qinli , Ren Zhigang , Wu Wenyu , Meng Tingwei , Wu Yinguang
Published: March 2024

With the rapid development of China’s urbanization process and the promotion of the ‘double carbon’ strategy, green buildings will become an inevitable trend in the future development of the construction industry. Among the various building evaluation criteria, it is important to discuss how to promote the development of green buildings more efficiently and adaptively according to the characteristics of personnel needs. This study constructed a questionnaire to assess building use satisfaction based on China’s national standards. Field research was conducted on 23 projects in six cities in Hubei Province, China, and a total of 2251 questionnaires were collected. The survey evaluated satisfaction with the current use of green buildings across different age groups and genders. A new satisfaction evaluation model is constructed through fuzzy comprehensive evaluation to provide guidance for the differentiated development of green buildings in different cities.
Seismic Vulnerability Analysis of Concrete-Filled Steel Tube Structure under Main–Aftershock Earthquake Sequences
Authors: Zhang Chunli , Li Jie , Liu Yangbing , Cheng Qing , Sun Zhuojun
Published: March 2024

Earthquakes are often followed by higher-intensity aftershocks, which tend to aggravate the accumulated and more severe damage to building structures. The seismic vulnerability of concrete-filled steel tube (CFST) structures under major aftershocks is more complex. In this paper, a CFST frame and a frame with buckling-restrained braces (BRBs) are studied, and the finite element analysis software Midas 2022 is used to analyze the seismic vulnerability of the two types of structures under main shock and main–aftershock. The results show that the structural vulnerability of the two structures is significantly higher under the main–aftershock sequences than under the main shock alone. Compared with the CFST structure, the structure with BRBs can effectively reduce the structural displacement and the hysteretic energy, decrease the plastic deformation risk of the structural components, and improve the seismic performance. The structure with BRBs can significantly reduce the probability of structural collapse under the main–aftershock sequence and can provide a reliable guarantee of the stability of the building.
Beauty and Utility in Architecture, Interior Design and in the New European Bauhaus Concepts
Authors: Nowakowski Przemyslaw
Published: March 2024

Appreciating beauty is a positive human feeling. In architecture and design, it is associated with the usefulness of products to meet needs. Those products are well received by users. The designer’s task is to achieve perfection in their work. The rational design of artificial living environments is also an expression of concern for a sustainable environment. The interdisciplinary New European Bauhaus is interested in these issues. This paper indicates the role of beauty and utility in the built environment. They are analyzed in the context of social and technical conditions and contemporary sustainable design. Its goal is to expand the knowledge of beauty and usefulness in architecture. They are increasingly important in the sustainable development of the built environment. This article uses research methods: interpretive research, analyses, comparisons, logical argumentation, etc. Innovative qualitative research in the form of a checklist is used. This survey can be used to rationally evaluate architecture and interior facilities. It can be helpful for various sustainable aesthetic and functional strategies dedicated to designers and users. It indicates possible directions for further assessment of architecture, e.g., in the context of management, environment and identity in the era of digitalization. It can be helpful in assessing the quality of the built environment.
Long-Term Analysis of Energy Consumption and Thermal Comfort in a Passivhaus Apartment in Spain
Authors: Rodríguez-Vidal Iñigo , Hernández-Minguillón Rufino J. , Otaegi Jorge
Published: March 2024

This study presents a detailed analysis of thermal comfort and energy consumption in a Passivhaus-certified apartment in Bolueta Tower, Bilbao, Spain, over a period of three years (2020–2022). Utilizing a comprehensive, long-term monitoring approach, the research investigates the effectiveness of the Passivhaus standard in achieving both energy efficiency and occupant comfort in a temperate climate. Using calibrated data loggers to record indoor temperature, humidity, and CO2 levels were used alongside the collection of utility bills to assess energy consumption and thermal comfort, as well as IAQ, against several international standards. Significant issues with overheating were confirmed, in line with previous research. During the warmer months, indoor temperatures frequently exceeded the Passivhaus comfort threshold of 25 °C, reaching as high as 31.3 °C, particularly in the living room and bedroom. This resulted in discomfort during summer, with the percentage of hours above 25 °C reaching 23.21% in 2022. Nighttime temperatures often surpassed 24 °C, impacting sleep quality. Conversely, heating consumption was minimal, corroborating the building’s energy efficiency in colder months. The findings highlight a critical gap in the Passivhaus standard when applied in milder climates, where overheating becomes a significant issue. This study suggests the need for an integrated approach in sustainable building design, one that balances energy efficiency with adaptive strategies to mitigate overheating, such as improved natural ventilation and thermal mass. These insights contribute to the ongoing discourse on optimizing energy-efficient buildings for occupant comfort in various climatic conditions.
The Quantification of Carbon Emission Factors for Residential Buildings in Yunnan Province
Authors: Li Wuyan , Li Qinyao , Zhang Chubei , Jin Sike , Wang Zhihao , Huang Sheng , Deng Shihan
Published: March 2024

The carbon emissions released from buildings are correlated with various factors in social and economic systems. Thus, quantifying and then controlling those factors can decrease the release of carbon emissions further. To quantify the influencing factors of the carbon emissions of residential buildings in Yunnan Province in China, separately for urban and rural areas, this study adopted the methods of utilizing the carbon emission factor and the LMDI model and combined them with the carbon emissions data obtained from 2010 to 2019. Subsequently, with this model, the contribution of each factor to the overall carbon emissions was quantified. The results demonstrate the following: (1) the main factors influencing carbon emissions from residential buildings include the per capita floor area, energy consumption per unit area, energy intensity effect, energy structure effect, urbanization rate, and population size. (2) For urban buildings, carbon emissions are negatively correlated with the energy consumption per unit area, energy intensity effect, and energy structure effect, with contribution values of 0.34, 0.27, and 0.05, respectively. Conversely, there is a positive correlation with the per capita floor area, urbanization rate, and population size, with contribution values of 0.23, 0.11, and 0.01, respectively. (3) For rural buildings, carbon emissions are negatively correlated with urbanization rate, energy intensity effect, and energy structure effect, with contribution values of 0.16, 0.15, and 0.14, respectively. Conversely, there is a positive correlation with the per capita floor area, energy consumption per unit area, and population size, with contribution values of 0.29, 0.24, and 0.02, respectively.
Real-Time Monitoring of Concrete Vibration Depth Based on RFID Scales
Authors: Quan Yuhu , Wang Xinzhi , Liu Yancheng , Sun Hongpeng , Wang Fenglai
Published: March 2024

The vibration of concrete is a typical concealed construction process, in which mature supervisory methods are lacking. The quality of vibration relies heavily on the subjective experience and sense of responsibility of the vibration operators. For the widely used hand-held concrete vibrators, existing methods for monitoring the quality of vibration primarily focus on the horizontal positioning of the vibrator. Due to the limited measurable range of vibration depth, these methods are inapplicable for monitoring the vibration depth during the vibration of deeper structures such as walls, columns, and large volumes of concrete. This paper makes the initial attempt to address the issue of monitoring concrete vibration depth, presenting a method that broadens the measurable range of depth in vibration monitoring. Inspired by the principles of optical and magnetic scales, this paper introduces a radio frequency identification (RFID) scales positioning system for the real-time monitoring of vibration depth. The proposed RFID scales vibration depth monitoring method theoretically has no upper limit on the measurable vibration depth, rendering it applicable to monitoring vibration depth of any extent. By comparing the positioning accuracy of different RFID scales hardware compositions, the optimal RFID scales hardware composition and the most effective RFID scales positioning algorithm were identified. The feasibility and accuracy of the vibration depth monitoring method based on RFID scales were validated through engineering field application. This method achieves centimeter-level accuracy in monitoring vibration depth, offers a tool for the precise control of vibration depth, and helps avoid potential quality issues in vibration.
Degradation of Seismic Performance of Thin Steel Plate Shear Walls in Earthquakes
Authors: Du Yipeng , Zhang Min , Cao Yifang , Xue Lei
Published: March 2024

Steel plate shear walls (SPSWs) are widely used in earthquake-prone areas, and they usually undergo multiple earthquakes throughout their service lives. The performances of SPSWs under a single shot of an earthquake have been widely studied, although the secondary seismic performance of earthquake-damaged structures remains unclear. Damage to an SPSW structure during an earthquake is difficult to evaluate. In this study, the degradation of the seismic performance of SPSWs during earthquakes was investigated. A test specimen was subjected to a two-stage quasistatic load. The plastic development and failure modes of SPSW specimens were investigated. The degradation of bearing capacity, stiffness, and energy dissipation performance was analyzed. On the basis of the experimental investigation, finite-element models introducing the ductile damage criterion and the cyclic constitutive model of steel were established. The degradation of the seismic performance of SPSWs under secondary earthquakes was studied. The results indicate that the stiffness of the SPSWs degrades more significantly than the bearing capacity. The larger the height-to-thickness ratio of the embedded plate, the more obvious the decrease in the bearing capacity, and the smaller the decrease in stiffness. With the increase in the maximum lateral displacement reached by the structure in an earthquake, and as the pinch phenomenon of the hysteresis curve of the SPSW becomes more serious, the energy dissipation capacity shows a uniform downward trend.
Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome
Authors: Di Giuseppe Fabrizio , Ricci-Vitiani Lucia , Pallini Roberto , Di Pietro Roberta , Di Iorio Patrizia , Ascani Giuliano , Ciccarelli Renata , Angelucci Stefania
Published: March 2024

Extracellular vesicles (EVs) are secreted from many tumors, including glioblastoma multiforme (GBM), the most common and lethal brain tumor in adults, which shows high resistance to current therapies and poor patient prognosis. Given the high relevance of the information provided by cancer cell secretome, we performed a proteomic analysis of microvesicles (MVs) and exosomes (EXOs) released from GBM-derived stem cells (GSCs). The latter, obtained from the brain of GBM patients, expressed P2X7 receptors (P2X7Rs), which positively correlate with GBM growth and invasiveness. P2X7R stimulation of GSCs caused significant changes in the EV content, mostly ex novo inducing or upregulating the expression of proteins related to cytoskeleton reorganization, cell motility/spreading, energy supply, protection against oxidative stress, chromatin remodeling, and transcriptional regulation. Most of the induced/upregulated proteins have already been identified as GBM diagnostic/prognostic factors, while others have only been reported in peripheral tumors. Our findings indicate that P2X7R stimulation enhances the transport and, therefore, possible intercellular exchange of GBM aggressiveness-increasing proteins by GSC-derived EVs. Thus, P2X7Rs could be considered a new druggable target of human GBM, although these data need to be confirmed in larger experimental sets.