bluuebunny/crossref_metadata_2025 huggingface dataset:
Domingo de Hondarra y su proyecto para el Monasterio de Nuestra Señora del Olivar de Estercuel (Teruel): un complejo mercedario de carácter italiano en las profundidades de Aragón
Authors: Calvo Asensio Juan Carlos , Millan Rabasa Marc
Published: June 2023

A partir de un documento localizado en el Archivo Histórico de Protocolos Notariales de Zaragoza analizamos la iglesia y el claustro del monasterio de Nuestra Señora del Olivar de Estercuel (Teruel). Adjudicamos el inicio de la construcción al arquitecto Domingo de Hondarra, de quien trazamos una biografía con numerosas novedades documentales. Asimismo, ahondamos en la influencia de la tratadística italiana del siglo XVI en la arquitectura aragonesa mediante el estudio de las yeserías de las bóvedas del complejo. Por último, delimitamos la implicación en este proyecto de Juan Cebrián, arzobispo de Zaragoza y virrey de Aragón, a los últimos momentos de la fábrica.
Deterministic relation between thermal-phonon dressings and Non-Hermitian multi-Fano interferences in ion-doped microcrystals
Authors: Fan Huanrong , Raza Faizan , Mujahid Anas , Wang Yafen , Tang Haitian , Usman Muhammad , Li Bo , Li Changbiao , Zhang Yanpeng
Published: June 2023

We report the multi-Fano interference obtained through the simultaneous acquisition of bright and dark states in different phase transitions of Eu3+: BiPO4 (7:1, 6:1, 1:1, and 0.5:1) and Eu3+: NaYF4 (1:1/4) crystals. We employ multi-dressed spontaneous four-wave mixing and multi-dressed fluorescence (multi-order) to optimize the strong photon-phonon nested dressing effect resulting in more obvious multi-Fano interference. Firstly, the multi-Fano is produced through interference in continuous and multi-bound states. Secondly, five multi-Fano dips originate from nested five dressings (one photon and four phonons) under symmetrical splitting of 7F1 energy level. We depict that the pure H-phase (0.5:1) sample exhibits the strongest photon-phonon dressed effect (five Fano dips). Further, we investigate high-order non-Hermitian exceptional points in multi-Fano interference by adjusting the ratio of Rabi-frequency to de-phase rate through nested photon and phonon dressing. Our experimental results are validated by theoretical simulations, which may be applied to designing optoelectronic devices such as multi-channel routers.
Fear memory recall involves hippocampal somatostatin interneurons
Authors: Zichó Krisztián , Sos Katalin E. , Papp Péter , Barth Albert M. , Misák Erik , Orosz Áron , Mayer Márton I. , Sebestény Réka Z. , Nyiri Gábor
Published: June 2023

Fear-related memory traces are encoded by sparse populations of hippocampal principal neurons that are recruited based on their inhibitory–excitatory balance during memory formation. Later, the reactivation of the same principal neurons can recall the memory. The details of this mechanism are still unclear. Here, we investigated whether disinhibition could play a major role in this process. Using optogenetic behavioral experiments, we found that when fear was associated with the inhibition of mouse hippocampal somatostatin positive interneurons, the re-inhibition of the same interneurons could recall fear memory. Pontine nucleus incertus neurons selectively inhibit hippocampal somatostatin cells. We also found that when fear was associated with the activity of these incertus neurons or fibers, the reactivation of the same incertus neurons or fibers could also recall fear memory. These incertus neurons showed correlated activity with hippocampal principal neurons during memory recall and were strongly innervated by memory-related neocortical centers, from which the inputs could also control hippocampal disinhibition in vivo. Nonselective inhibition of these mouse hippocampal somatostatin or incertus neurons impaired memory recall. Our data suggest a novel disinhibition-based memory mechanism in the hippocampus that is supported by local somatostatin interneurons and their pontine brainstem inputs.
Bone impact after two years of low-dose oral contraceptive use during adolescence
Authors: Orsolini Lilian Rodrigues , Goldberg Tamara Beres Lederer , Caldeirão Talita Domingues , Cristiane da Silva Carla , Rizzo Anapaula da Conceição Bisi , Biason Talita Poli , Teixeira Altamir Santos , Carvalho Nunes Helio Rubens
Published: June 2023

Objective

Data regarding the use and effect of hormonal contraceptives on bone mass acquisition during adolescence are contradictory. The present study was designed to evaluate bone metabolism in two groups of healthy adolescents using combined oral contraceptives (COC).

Methods

A total of 168 adolescents were recruited from 2014 to 2020 in a non-randomized clinical trial and divided into three groups. The COC1 group used 20 μg Ethinylestradiol (EE)/150 μg Desogestrel and the COC2 group used 30 μg EE/3 mg Drospirenone over a period of two years. These groups were compared to a control group of adolescent non-COC users. The adolescents were submitted to bone densitometry by dual-energy X-ray absorptiometry and measurement of bone biomarkers, bone alkaline phosphatase (BAP), and osteocalcin (OC) at baseline and 24 months after inclusion in the study. The three groups studied were compared at the different time points by ANOVA, followed by Bonferroni’s multiple comparison test.

Results

Incorporation of bone mass was greater in non-users at all sites analyzed (4.85 g in lumbar Bone mineral content (BMC)) when compared to adolescents of the COC1 and COC2 groups, with a respective increase of 2.15 g and loss of 0.43g in lumbar BMC (P = 0.001). When comparing subtotal BMC, the control increased 100.83 g, COC 1 increased 21.46 g, and COC 2 presented a reduction of 1.47 g (P = 0.005). The values of bone markers after 24 months are similar for BAP, being 30.51 U/L (± 11.6) for the control group, 34.95 U/L (± 10.8) for COC1, and 30.29 U/L for COC 2 (± 11.5) (P = 0.377). However, when we analyzed OC, we observed for control, COC 1, and COC 2 groups, respectively, 13.59 ng/mL (± 7.3), 6.44 ng/mL (± 4.6), and 9.48 ng/mL (± 5.9), with P = 0.003. Despite loss to follow-up occurring in the three groups, there were no significant differences between the variables in adolescents at baseline who remained in the study during the 24-month follow-up and those who were excluded or lost to follow-up.

Conclusion

Bone mass acquisition was compromised in healthy adolescents using combined hormonal contraceptives when compared to controls. This negative impact seems to be more pronounced in the group that used contraceptives containing 30 μg EE.

Clinical trial registration

http://www.ensaiosclinicos.gov.br, RBR-5h9b3c. “Low-dose combined oral contraceptive use is associated with lower bone mass in adolescents”.
Assessment of vaccine perception and vaccination intention of Mpox infection among the adult males in Bangladesh: A cross-sectional study findings
Authors: Islam Md. Rabiul , Haque Md. Anamul , Ahamed Bulbul , Tanbir Md. , Khan Md. Robin , Eqbal Saba , Rahman Md. Ashrafur , Shahriar Mohammad , Bhuiyan Mohiuddin Ahmed
Published: June 2023

Background

Mpox (monkeypox) infection has become a global concern for healthcare authorities after spreading in multiple non-endemic countries. Following the sudden multi-country outbreak of Mpox, the World Health Organization (WHO) declared a public health emergency of international concern. We do not have any vaccines approved for the prevention of Mpox infection. Therefore, international healthcare authorities endorsed smallpox vaccines for the prevention of Mpox disease. Here we intended to perform this cross-sectional study among the adult males in Bangladesh to assess the Mpox vaccine perception and vaccination intention.

Methods

We conducted this web-based survey among the adult males in Bangladesh from September 1, 2022, to November 30, 2022, using Google Forms. We assessed the Mpox vaccine perception and vaccination intention. We performed a chi-square test to compare vaccine perception and vaccination intention levels. Also, we performed multiple logistic regression analyses to determine the association between the study parameters and the sociodemographic profile of the participants.

Results

According to the present study, the Mpox vaccine perception was high among 60.54% of the respondents. Also, 60.05% of respondents showed medium vaccination intention. Mpox vaccine perception and vaccination intention were strongly associated with the sociodemographic profiles of the participants. Furthermore, we discovered a significant association between the level of education and vaccination intention among the respondents. Also, age and marital status played a role in the Mpox vaccine perception and vaccination intention.

Conclusion

Our findings showed a significant association between sociodemographic characteristics and the Mpox vaccine perception/vaccination intention. Along with the country’s long experience in mass immunization, campaigns about Covid-19 vaccines and high vaccination rates might play a role in Mpox vaccine perception and vaccination intention. We recommend more social awareness and educational communications or seminars for the target population to bring more positive changes in their attitude towards Mpox prevention.
Analytic solution to swing equations in power grids with ZIP load models
Authors: Oh HyungSeon
Published: June 2023

Objective

This research pioneers a novel approach to obtain a closed-form analytic solution to the nonlinear second order differential swing equation that models power system dynamics. The distinctive element of this study is the integration of a generalized load model known as a ZIP load model (constant impedance Z, constant current I, and constant power P loads).

Methods

Building on previous work where an analytic solution for the swing equation was derived in a linear system with limited load types, this study introduces two fundamental novelties: 1) the innovative examination and modeling of the ZIP load model, successfully integrating constant current loads to augment constant impedance and constant power loads; 2) the unique derivation of voltage variables in relation to rotor angles employing the holomorphic embedding (HE) method and the Padé approximation. These innovations are incorporated into the swing equations to achieve an unprecedented analytical solution, thereby enhancing system dynamics. Simulations on a model system were performed to evaluate transient stability.

Results

The ZIP load model is ingeniously utilized to generate a linear model. A comparison of the developed load model and analytical solution with those obtained through time-domain simulation demonstrated the remarkable precision and efficacy of the proposed model across a range of IEEE model systems.

Conclusion

The study addresses the key challenges in power system dynamics, namely the diverse load characteristics and the time-consuming nature of time-domain simulation. Breaking new ground, this research proposes an analytical solution to the swing equation using a comprehensive ZIP model, without resorting to unphysical assumptions. The close-form solution not only assures computational efficiency but also preserves accuracy. This solution effectively estimates system dynamics following a disturbance, representing a significant advancement in the field.
Determinants of diabetic retinopathy in Ethiopia: A systematic review and meta-analysis
Authors: Azagew Abere Woretaw , Yohanes Yeneabat Birhanu , Beko Zerko Wako , Ferede Yohannes Mulu , Mekonnen Chilot Kassa
Published: June 2023

Introduction

Diabetic retinopathy (DR) is the primary retinal vascular complication of diabetes mellitus and a leading cause of visual impairment and blindness. It affects the global diabetic population. In Ethiopia, about one-fifth of diabetic patients were affected by DR, but there were inconsistent finding across studies about the determinants factors of DR. Therefore, we aimed to identify the risk factors for DR among diabetic patients.

Methods

We have accessed previous studies through an electronic web-based search strategy using PubMed, Google (Scholar), the Web of Science, and the Cochrane Library with a combination of search terms. The quality of each included article was assessed using the Newcastle Ottawa Assessment Scale. All statistical analyses were carried out using Stata version 14 software. The odds ratios of risk factors were pooled using a fixed-effect meta-analysis model. Heterogeneity was assessed using the Cochrane Q statistics and I-Square (I2). Furthermore, publication bias was detected based on the graphic asymmetry test of the funnel plot and/or Egger’s test (p< 0.05).

Results

The search strategy retrieved 1285 articles. After the removal of duplicate articles, 249 articles remained. Following further screening, about 18 articles were assessed for eligibility, of which three articles were excluded because of reporting without the outcome of interest, poor quality, and not full text. Finally, fifteen studies were reviewed for the final analysis. Co-morbid hypertension (HTN) (AOR 2.04, 95%CI: 1.07, 3.89), poor glycemic control (AOR = 4.36, 95%CI: 1.47, 12.90), and duration of diabetes illness (AOR = 3.83, 95%CI: 1.17, 12.55) were found to be confirmed associated factors of diabetic retinopathy.

Conclusion

In this study, co-morbid HTN, poor glycemic control, and longer duration of diabetes illness were found to be the determinant factors of DR. Aggressive treatment of co-morbid HTN and blood glucose, and regular eye screening should be implemented to reduce the occurrence of DR.

Trial registration

The review protocol was registered in the international prospective register of systematic reviews (PROSPERO) with registration number PROSPERO:CRD42023416724.
In-silico modelling of the impact of hypertension on the mean transvalvular gradients in aortic stenosis
Authors: Liebenberg Jacques , Doubell Anton , Laubscher Ryno , Herbst Philip
Published: June 2023

Introduction

The influence of hypertension on the diagnostic assessment of aortic stenosis (AS) severity is unclear, yet clinically relevant. To clarify the effect of hypertension on transvalvular gradients, requires a better understanding of the impact that blood pressure change has on mean flow rate. Also, the effect of various degrees of AS severity, the valve geometry and intrinsic left ventricular contractile function (elastance) on this interaction, needs to be clarified. The current work aims to assess this interaction and the magnitude of these effects.

Methods

A validated, zero-dimensional electro-hydraulic analogue computer model of the human cardiovascular circulatory system was generated. It was used to assess the impact of blood pressure changes on left ventricular pressure and transvalvular gradients at various flow rates, left ventricular elastances, a range of aortic valve areas and for different aortic valve morphologies.

Results and discussion

The magnitude of the impact of hypertension induced changes on the mean gradient (MG) is influenced by the mean flow rate, the AS severity, the hydraulic effective valve orifice area and the left ventricular elastance. Generally, for a given change in systemic arterial pressure, the impact on MG will be the most marked for lower flow rate states such as is expected in more severe degrees of AS, for worse intrinsic left ventricular (LV) contractility, shorter ejection times and lower end diastolic LV volumes. Given the above conditions, the magnitude of the effect will be more for a larger aortic sinus diameter, and also for a typical degenerative valve morphology compared to a typical rheumatic valve morphology.

Conclusion

The interaction between hypertension and mean gradients in AS is complex. The current work places previous recommendations in perspective by quantifying the magnitude of the effect that the changes in blood pressure has on mean gradient in various pathophysiological states. The work creates a framework for the parameters that should be considered in future clinical research on the topic.
Association between pseudoexfoliation and Alzheimer’s disease-related brain atrophy
Authors: Jeong Won Cheol , Min Jin-Young , Kang Tae Gu , Bae Heewon
Published: June 2023

Background/aims

Pseudoexfoliation (PEX) syndrome is an age-related disorder characterized by the accumulation of extracellular material in the anterior eye segment. PEX pathogenesis is not fully understood, but amyloid which accumulates in the brain of patients with Alzheimer’s disease (AD) is a PEX component. PEX deposition shares features with amyloid aggregation in AD, and brain atrophy is a common AD feature, with β-amyloid accumulation among contributing factors. This study investigated whether PEX syndrome is associated with AD-related brain atrophy.

Methods

We reviewed the medical records of patients diagnosed with PEX at the Veterans Health Service Medical Center between January 2015 and August 2021. This retrospective cohort study included 48 patients with PEX and 48 healthy age- and sex-matched controls. Patients with PEX were divided into two groups: with and without glaucoma. The main outcome measure was brain atrophy, using a visual rating scale, and AD incidence. Brain atrophy was measured using the Scheltens scale for medial temporal atrophy, the posterior cortical atrophy scale for parietal atrophy, and the Pasquier scale for global cortical atrophy.

Results

The percentage of participants with medial temporal atrophy was 56.3% in the PEX group and 35.4% in the control group. The global cortical atrophy and parietal atrophy scores were significantly higher in the PEX group (P<0.05), whereas the PEX and PEX glaucoma groups showed no difference. Among the 96 participants, 16 and 5 participants in the PEX and control groups, respectively, were diagnosed with dementia. Patients with PEX glaucoma tended to have lower Mini-Mental State Examination scores, indicating impaired cognitive function, than those without glaucoma.

Conclusion

PEX is associated with brain atrophy, reflecting the risk of developing AD. Patients with PEX glaucoma may present with advanced AD stages. Our results suggest that PEX may be a predictor of AD.
The effect of psychological factors on financial behaviour among older Australians: Evidence from the early stages of COVID-19 pandemic
Authors: Arya Vandana , Banerjee Rajabrata , Lowies Braam , Viljoen Christa , Lushington Kurt
Published: June 2023

The current study investigated the association between psychological factors and financial behaviour during the COVID-19 pandemic in older people. Older people were chosen compared to other age groups because of the relatively greater impact in this age group of suboptimal financial decisions on future financial wellbeing. We hypothesised that the psychological factors facilitating general wellbeing during the COVID-I9 pandemic, i.e., positive mental wellbeing, hope, and positive coping, will have positive effects on financial behaviour. Based on telephone interviews, 1501 older Australians (Men = 750 and Women = 751; 55-64y = 630; > 65y = 871) completed an omnibus questionnaire examining coping, hope, mental wellbeing, and financial behaviour. Data was analysed using logistic regression and an ordinary and two-stage least square frameworks. Analyses revealed that the psychological factors identified as facilitating general wellbeing during the COVID-I9 pandemic also facilitated positive financial behaviour with hope and mental wellbeing emerging as significant determinants. Based on weightings from principal component analysis, one item each from the hope and mental wellbeing scale with eigenvalues > 1 were found to be robust predictors of positive financial behaviours. In conclusion, the findings support the assumption that the psychological factors associated with general wellbeing during the COVID-19 pandemic are also associated with positive financial behaviour. They further raise the possibility that single hope and positive mental well-being items can also be used to monitor psychological health and predict financial behaviour in older people and, in particular, at times of crisis. The latter may be useful measures for government to monitor psychological and financial wellbeing and inform policy for supporting older people at times of crisis.
Thermostable chaperone-based polypeptide biosynthesis: Enfuvirtide model product quality and protocol-related impurities
Authors: Zenin Vladimir , Tsedilin Andrey , Yurkova Maria , Siniavin Andrey , Fedorov Alexey
Published: June 2023

Large peptide biosynthesis is a valuable alternative to conventional chemical synthesis. Enfuvirtide, the largest therapeutic peptide used in HIV infection treatment, was synthesized in our thermostable chaperone-based peptide biosynthesis system and evaluated for peptide quality as well as the profile of process-related impurities. Host cell proteins (HCPs) and BrCN cleavage-modified peptides were evaluated by LC-MS in intermediate. Cleavage modifications during the reaction were assessed after LC-MS maps were aligned by simple in-house algorithm and formylation/oxidation levels were estimated. Circular dichroism spectra of the obtained enfuvirtide were compared to the those of the chemically- synthesized standard product. Final-product endotoxin and HCPs content were assessed resulting 1.06 EU/mg and 5.58 ppm respectively. Peptide therapeutic activity was measured using the MT-4 cells HIV infection-inhibition model. The biosynthetic peptide IC50 was 0.0453 μM while the standard one had 0.0180 μM. Non-acylated C-terminus was proposed as a cause of IC50 and CD spectra difference. Otherwise, the peptide has met all the requirements of the original chemically synthesized enfuvirtide in the cell-culture and in vivo experiments.
Cultura y paisaje a través de la historia de Porto das Catraias (Educandos)
Authors: Ramos de Brito Souto Calina , De Lima Pedrosa Santos Tatiana
Published: June 2023

El proceso de urbanización de la ciudad de Manaos (Amazonas, Brasil), así como de otras capitales brasileñas, se llevó a cabo considerando el entorno natural como un obstáculo para el desarrollo, y así todo quedó devastado a favor de un modelo de ciudad ideal y moderno que respondiera a la demanda del desarrollo económico. El artículo busca discutir la relación hombre versus naturaleza, mostrando cómo esta relación puede ser positiva y armoniosa, pero también devastadora, como se puede ver en la historia del urbanismo de Manaos, recurriendo al tramo que comprende el borde del Bairro Educandos para componer el discurso. Asimismo, se abordan puntos que buscan reflexionar sobre las posibles soluciones que puede pensar y desarrollar el urbanismo para el futuro, para que sea sostenible.
Veinte años después
Authors: Berdugo Gómez de la Torre Ignacio , Santos Pérez José Manuel
Published: June 2023

En junio de 2001, la Junta de Gobierno de la Universidad de Salamanca adoptó el acuerdo de creación del Centro de Estudios Brasileños (CEB), que tendría como objetivo impulsar las relaciones académicas de Salamanca con las instituciones brasileñas de educación superior y difundir en España el conocimiento de todo aquello que da contenido a la identidad brasileña. Desde entonces, han pasado veinte años, en los que Centro ha desarrollado un importante trabajo académico y cultural, plasmado en numerosísimas actividades y colaboraciones, y divulgado desde su nueva sede en el Palacio de Maldonado, pero también, de forma más internacional, a través de los medios que pone a nuestra disposición la tecnología. Hoy, el CEB prosigue su andadura más fuerte que nunca y con vocación de futuro, dispuesto a seguir estrechando lazos entre ambos lados del Atlántico.
Infraestructura de transporte y modelos de acumulación en la región centro de Argentina. Aportes para el estudio del Corredor Bioceánico Porto Alegre- Santa Fe- Coquimbo
Authors: Acebal Anahí , Álvarez Álvaro
Published: June 2023

Durante la primera década del siglo XXI, luego del colapso del modelo de acumulación neoliberal, se desarrollaron en América Latina planes y programas de infraestructura que buscaron re-adaptar la infraestructura existente a las nuevas dinámicas de circulación de flujos, sobre todo a partir de un aumento en la exportación de commodities y un incremento de la demanda internacional de materias primas.

Estos planes, iniciativas y programas – la Iniciativa para la Integración en Infraestructura Regional Suramericana, el Plan Puebla Panamá, el Consejo Suramericano de Infraestructura y Planeamiento, entre otros- fueron re-diseñando la geografía regional en función de nuevos corredores. En tal sentido, en la actualidad, la logística multimodal y la bi-oceanidad en la circulación son aspectos destacados del transporte regional y se emplazan en los territorios infraestructuras de gran porte con el objetivo de garantizar fluidez (puertos, aeropuertos, autovías, túneles, vías férreas, ductos, gasoductos, etc).

La región centro de la Argentina –integrada por las provincias de Entre Ríos, Santa Fe y Córdoba- es un importante ejemplo de esa re-adaptación en la circulación con la pretensión de construir un corredor bi-oceánico articulado multimodalmente con la hidrovía Paraguay- Paraná, que es la vía exportadora más importante de la Argentina.

El siguiente trabajo analiza cómo la infraestructura exportadora se articula y desarrolla en un territorio nodal en la expansión del modelo de acumulación dominante en la Argentina caracterizado por la reprimarización productiva, la concentración económica y la extranjerización.

Con ese propósito analítico el objetivo general de este trabajo es estudiar la manera en que las actividades productivas y fundamentalmente el comercio internacional, en un contexto histórico marcado por la fragmentación de la producción y de incremento de los flujos globales, impulsan la construcción de determinados macrosistemas de infraestructura, que son condicionantes en la organización social y económica del territorio.

La pregunta metodológica que guió esta investigación es qué infraestructura se promueve en la región centro y para qué modelo de acumulación. El resultado al que arriba este trabajo, se abona con otras investigaciones desarrolladas y en curso, y pone de manifiesto que los programas de infraestructura hegemónicos no promueven la integración del territorio regional -por el contrario, fragmentan territorialidades preexistentes- sino la articulación de la producción primaria de la región con las necesidades de los principales centros industrializados.
Woman’s Leadership in Islamic Psychological Perspective
Authors: Hidayat Muslim , Cahyani Putri Maulida Dwi , Ahmadiyati Jihan Nurrizki , Bobihu Nursyahdina Al-Rahmah , Maknuna Luluk
Published: June 2023

Essence of justice and gender equality cannot be separated from the context of society's understanding of the roles and place of men and women in the social realities of society. People still understand that gender is a cultural construct of roles, functions, and social responsibility between men and women. In general, beings in the women's world experience marginalization in both social and personal spheres. Alienation, injustice, and even ignoring women feel very common among men. The bad view of women throughout history has led to a bad view of all aspects of women. All religions, especially Islam, face new challenges. Islam is considered to perpetuate injustice and oppression of women, including patterns of male-female relationship (gender inequality). The problem, however, is that these gender inequalities stem either from religion itself, or from religious interpretations or understandings influenced by patriarchal traditions or cultures, capitalist ideologies or medieval Middle Eastern cultures. From the Islamic point of view, leadership is related to two basic social expectations or demands placed on leaders. The purpose of this study is to inform readers about the meaning of women's leadership, the challenges of leaders, and aspects of leadership by examining them from the perspective of Islam and Islamic psychology. The method used in this study is the use of a literacy research method, or commonly referred to as a literature study, and is sourced from data obtained by recording and processing the research data obtained.Keywords: Leadership, Woman, Islamic Psychological Perspective.
THE INFLUENCE OF YOUTUBE CONTENT EXPOSURE ON GEN Z RELIGIOSITY IN JAVA AND SUMATRA
Authors: Rubiyanah Rubiyanah , Fadhilla Indah , Zen Muhamad
Published: June 2023

At the beginning of YouTube development, there were few broadcasts featuring information about religious values. But now, along with the times, many preachers are starting to use YouTube as a medium of da'wah to reach the younger generation who may not come to conventional recitations such as lectures in recitation activities. Based on this background, this study aims to measure the effects of YouTube, especially da'wah shows, on the younger generation’s religiosity at universities in Java and Sumatra. The religiosity aspect consists of Aqidah, morals, and sharia. These three aspects will be used as variables revealed to be questioned for respondents. The research method used in this study is the SEM (Structural Equation Modeling) analysis technique. Data collection in the study was conducted at four campuses: UIN Syarif Hidayatullah Jakarta, Pamulang University (UNPAM) and UIN Imam Bonjol Padang and Padang State University (UNP), with a sample of 200 students representing Gen-Z. Sampling used simple random sampling. The research results obtained a significance score of 0.031 < 0.05 so that it can be concluded; First, the preachers (YouTube) figure has little effect on the religiosity of Gen-Z, namely the preachers is only 0.019, meaning that the effect is small. On YouTube, the second theory, preaching, affects Gen-Z religiosity by 0.093, meaning that the effect is negligible. Third, the da'wah method on YouTube involves the religiosity of Gen-Z, which is equal to 0.131, which means that the method is more influential than the preacher and material. This means that the hypothesis is accepted or has a significant effect, especially on the da'wah method.
Determinants of joint stiffness and jumping height during drop jump
Authors: Kosaka Takehiro , Sasajima Shuhei , Yasuda Ayaka , Mino Soushi , Kubo Keitaro
Published: June 2023

The present study aimed to examine the effects of muscle‐tendon mechanical properties and electromyographic activity on joint stiffness and jumping height and to explore the determinants of joint stiffness and jumping height. Twenty‐nine males performed unilateral drop jumps at three drop heights (10, 20, and 30 cm) using only the ankle joint on the sledge apparatus. Ankle joint stiffness, jumping height, and electromyographic activity of the plantar flexor muscles were measured during drop jumps. Active muscle stiffness of the medial gastrocnemius muscle was calculated according to changes in the estimated muscle force and fascicle length during fast stretching at five different angular velocities (100, 200, 300, 500, and 600 deg s−1) after submaximal isometric contractions. Tendon stiffness and elastic energy were measured during ramp and ballistic contractions. Active muscle stiffness was significantly correlated with joint stiffness, except for a few conditions. Tendon stiffness measured during ramp and ballistic contractions was not significantly correlated with joint stiffness. The ratios of electromyographic activity before landing and during the eccentric phase to that during the concentric phase were significantly correlated with joint stiffness. In addition, jumping heights at 10 and 20 cm (except for 30 cm) drop heights were strongly associated with the tendon elastic energy, whereas no other measured variables showed significant correlations with jumping heights. These results suggested that (1) joint stiffness is determined by active muscle stiffness and electromyographic activity patterns during jumping, and (2) jumping height is determined by tendon elastic energy.
Performance optimization of geopolymer mortar blending in nano-SiO2 and PVA fiber based on set pair analysis
Authors: Zhang Peng , Zhang Xuemei , Yuan Peng , Hu Shaowei
Published: June 2023

The method of set pair analysis was used to evaluate the comprehensive performance of geopolymer mortar (GM) based on metakaolin and fly ash modified by nano-SiO2 (NS) and polyvinyl alcohol (PVA) fiber, and the design of mix proportion for GM was optimized. According to the experimental results, the addition of the NS and PVA fiber can improve the comprehensive properties of GM. The properties of GM are better when the NS content is 1.5% and PVA fiber content is 0.6%. The comprehensive performance of GM included workability, mechanical properties, fracture properties, and durability, and the typical performance parameters were selected as slump flow, compressive strength, bending strength, fracture energy, loss ratio of compressive strength after cycles of freezing-thawing, and electric flux values. The results show that the weights of each indicator derived from the method of set pair analysis have reduced subjective arbitrariness, improved the evaluation accuracy, and made the conclusions obtained from the set pair analysis method more scientific and reasonable. The method of set pair analysis combines the mechanical properties, durability, and workability of GM blending in PVA fiber and NS to achieve a comprehensive qualitative and quantitative evaluation, which can provide a new method for assessing the comprehensive performance of the GM composites blending in PVA fiber and NS in the future.
Network pharmacology combined with molecular docking and experimental validation to reveal the pharmacological mechanism of naringin against renal fibrosis
Authors: Zhong Yanan , Li Xiang , Xie Juan , Zhang Yiyuan , Li Hailun , Zheng Donghui
Published: June 2023

To explore the pharmacological mechanism of naringin (NRG) in renal fibrosis (RF) based on network pharmacology combined with molecular docking and experimental validation. We used databases to screen for the targets of NRG and RF. The “drug-disease network” was established using Cytoscape. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of targets were performed using Metascape, and molecular docking was performed using Schrödinger. We established an RF model in both mice and cells to validate the results of network pharmacology. After screening the database, we identified 222 common targets of NRG and RF and established a target network. Molecular docking showed that the target AKT had a good interaction with NRG. We found that the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway was enriched by multiple targets and served as a target for experimental validation through GO and KEGG. The results revealed that NRG ameliorated renal dysfunction, reduced the release of inflammatory cytokines, decreased the expression of α-SMA, collagen I, and Fn, and recovered the expression of E-cad by inhibiting the PI3K/AKT signaling pathway. Our study used pharmacological analysis to predict the targets and mechanisms of NRG against RF. Furthermore, experiments proved that NRG inhibited RF effectively by targeting the PI3K/AKT signaling pathway.
Some Practical Aspects of Nanocellulose Film: Characterization, Expansion and Shrinking Tests, and Techniques to Create Remoistenable Nanocellulose
Authors: Canham Robin , Murray Alison , Hill Rosaleen
Published: June 2023

Microfibrillated cellulose (MFC), commonly referred to as nanocellulose, is an emerging conservation material with significant potential for application in a wide range of conservation treatments. Due to its properties of transparency and mechanical strength, nanocellulose film offers novel potential when thin tissues may not be suitable. However, when water or aqueous adhesives are applied to nanocellulose, it loses stability and becomes pulpy, making practical use problematic. Additionally, nanocellulose film can shrink upon drying, causing planar deformation. For these reasons, adhesives used with nanocellulose are limited in published treatments to date. The nanocellulose film used in this study was characterized and expansion and shrinking tests were conducted to better understand how nanocellulose film reacts when water and ethanol are introduced. The potential of using nanocellulose film in a remoistenable form is also explored. Results found that nanocellulose film behaved differently than Japanese tissue when water was introduced. While each expanded when water was introduced, the nanocellulose film shrunk 11 % from its initial size when dry, whereas the Japanese tissue returned to its initial size. Practical techniques are recommended to create remoistenable nanocellulose film with a selection of adhesives. Notably, remoistenable nanocellulose films created with methylcellulose and gelatine showed promising initial results.
Cooperação educacional China-Brasil: situação atual, desafios e perspetivas
Authors: Zhang Fangfang , Pang Ruoyang
Published: June 2023

À medida que as relações entre a China e o Brasil se aprofundam, as duas partes reforçam a sua cooperação nos domínios político, econômico e comercial. Neste processo, os intercâmbios culturais e educacionais têm sido valorizados por ambas as partes como uma via importante de promover o contato interpessoal e a aprendizagem mútua entre as duas culturas. Desde 1985, ano em que foi assinado o primeiro acordo de intercâmbio no domínio da educação entre os dois países, a cooperação educacional sino-brasileira começou a se expandir e têm se destacado as seguintes características: diversificação de conteúdos e formas de cooperação educacional; formação de um enquadramento de cooperação que engloba atores e níveis diversificados; aumento de quantidade e qualidade do ensino de línguas; e a ascensão da educação temática como instrumento de promover a aprendizagem mútua entre as culturas chinesa e brasileira. Nas últimas décadas, a cooperação educacional China-Brasil alcançou resultados variados, porém, esta continua enfrentando alguns desafios práticos, tais como a falta de institucionalização, a necessidade de alargar constantemente a sua quantidade e qualidade e a exigência de um conhecimento mútuo mais aprofundado sobre as realidades de educação das duas partes. No futuro, os dois países poderão reforçar a cooperação educacional e beneficiar ambos os povos por meio de promover a construção de mecanismos de cooperação relevantes, se focar mais na garantia de qualidade da cooperação, aprofundar os respetivos estudos sobre países e regiões, estabelecer banco de recursos de educação online e reforçar a cooperação no ensino profissional.
Synthesis, structure, and reactivity of the ferrocene-based N-heterocyclic stannylene [Fe{(η
5-C5H4)NC6H3-2,6-iPr2}2Sn]
Authors: Weyer Nadine , Bruhn Clemens , Siemeling Ulrich
Published: June 2023

The N-heterocyclic stannylene [Fe{(η
5-C5H4)NC6H3-2,6-iPr2}2Sn] (1) has been synthesised from SnCl2 and the lithium amide [Fe{(η
5-C5H4)NC6H3-2,6-iPr2}2Li2]. Compound 1 is inert towards H2, CO, CO2, and MeI under ambient conditions. Immediate hydrolysis and ammonolysis was observed with H2O and NH3, respectively. While oxidation reactions of 1 with chalcogens (O2, S8, Se8) afforded only intractable material, the reaction with Ph2Se2 cleanly furnished [Fe{(η
5-C5H4)NC6H3-2,6-iPr2}2Sn(SePh)2] (2). Compounds 1 and 2 have been structurally characterised by single-crystal X-ray diffraction. Compound 2 exhibits an intramolecular CH⋯Se contact compatible with a weak hydrogen bond.
Öğretmenlik Uygulaması Deneyim Ölçeği-Matematik: Geçerlik ve Güvenirlik Çalışması
Authors: ALBAYRAK H. Beyza , TARIM Kamuran , HACIÖMEROĞLU Güney
Published: June 2023

Bu araştırma, sınıf öğretmeni adaylarının matematik öğretimine ilişkin deneyimlerini belirlemek amacıyla bir ölçme aracı geliştirilmesini amaçlamaktadır. Sınıf öğretmeni adaylarının staj uygulamaları sırasında matematik öğretmede karşılaştıkları güçlükler, matematik derslerinde yaşadıkları olumlu ve olumsuz deneyimler ve etkili bir matematik öğretimi yapılabilmesi için staj uygulamaları derslerine ilişkin önerileri kapsamındaki görüşleri, bu ölçek geliştirme çalışmasının ölçek maddelerini oluşturmaktadır. Bu kapsamda veriler, 302 sınıf öğretmeni adayından toplanmıştır. Ölçeğin geçerlik çalışmaları için açımlayıcı ve doğrulayıcı faktör analizi uygulanmıştır. Güvenirlik çalışmaları için Cronbach alfa güvenirlik katsayıları hesaplanmıştır. Bu doğrultuda geliştirilen ölçek 21 maddeden oluşmaktadır ve 5’li Likert tipindedir. Ölçekte dönüt alma, öğretim güçlükleri, iletişim ve sınıf yönetimi, öğretim kaygısı ile sınıf öğretmenin rolü olmak üzere 5 alt boyut yer almaktadır. Ölçek alt boyutları için Cronbach alfa güvenirlik katsayıları sırasıyla .877, .836, .815, .726 ve .710 olarak hesaplanmıştır. Ölçeğin bütünü için güvenirlik katsayısı .853 olarak belirlenmiştir. Elde edilen sonuçlar Cronbach alfa güvenirlik katsayıları değerin .8 üzerinde oluşu ölçeğin yüksek derecede güvenilir olduğu şeklinde nitelendirilmektedir. Doğrulayıcı faktör analizi sonucunda beş faktörlü model için kabul edilebilir düzeyde uyum gösterdiği belirlenmiştir. Bu doğrultuda, geliştirilen ölçeğin sınıf öğretmeni adaylarının matematik öğretimine ilişkin deneyimlerini belirlemek amacıyla kullanılabilecek geçerli ve güvenilir bir ölçme aracı olduğunu ortaya koymuştur.
Views and Experiences of Pre-Service Science Teachers on the Use of Technology in Teaching and Learning of Electric Concepts
Authors: Nandipha Nyangiwe , Rankhumise Mmushetji , Sedumedi Thomas
Published: June 2023

The aim of the study was to explore pre-service science teachers’ views and experiences on the use of technology in teaching and learning of electric concepts. . The study sample consisted of six pre-service science teachers enrolled in Physical Science level 1 at a university of technology in South Africa, who aspire to be Physical Science teachers, and whose curriculum consist of electricity. The study adopted a case study research design embedded within the qualitative research approach. Data for the study was collected voluntarily from participants in alignment with the convenience sampling technique. The results of the study indicate the need for educators to have technology integration strategies because some schools lack equipment needed to conduct experiments. Moreover, pre-service science teachers recommend the use of technology integration because it is cheaper, safer, and more convenient
Análisis de política exterior en un contexto cambiante: Una aproximación
Authors: Murillo-Zamora Carlos
Published: June 2023

The foreign policy constitutes a particular field of study, attracting the attention of academics and research centers due to its intermestic nature (formulated in the internal or domestic sphere and implemented in the international or external sphere) and because it results from the contributions of International Relations, Political Science and Public Administration. Thus, it constitutes a bridge discipline of International Relations. In addition, its definition and characterization are complex since depend on how the State that formulates and implements it perceives itself; but also, because it relies on the type of State actor in question. A great power is not the same as a small State; necessary to highlight more than three-quarters of the countries in the international system are small agents. For this reason, since the mid-twentieth century, the interest of international analysts has focused on this field. In the same way, the analysis of foreign policy, as a research space, has shown an important evolution, requiring novel approaches and methodologies. On the other hand, the changes in the international system, particularly the end of the Cold War and the attacks of the so-called 9-11, introduced variants in the approach to this issue. However, it was with the SARS-CoV-2 pandemic and the war in Ukraine that reality has become more complex and demands new perspectives for analyzing foreign policy, especially of great powers and small states. Then, this article reviews the main texts on foreign policy, from the mid-last century and up to what was published this year (2023). The intention is to offer a sort of state-ofthe-art, for those who are interested in dabbling in the analysis of foreign policy and identifying the main ideas and approaches for subsequent research work
Experimientación y arqueología en la Península Ibérica
Authors: Baena Preysler Javier , Dapena Albiach Laura , Martín Puig Diego
Published: June 2023

Uno de los aspectos más relevantes en la práctica de la experimentación dentro de la arqueología ha sido la falta de centros de investigación de referencia dentro de nuestro ámbito. A diferencia de nuestro país, en general, el norte de Europa ha impulsado con mayor intensidad este tipo de procedimientos como línea fuerte de la investigación. Desde los años 70, países como Francia, Reino Unido, Dinamarca, Bélgica o la propia Alemania, han sabido aprovechar las ventajas de esta corriente metodológica tanto en sus aspectos más vinculados con la investigación, como en los relacionados con la difusión y la divulgación. Sí ello podría tener explicación para el caso británico o danés por ser cunas de esta disciplina, no se explica de la misma manera en el resto de los casos, o más aún, fuera del ámbito europeo (baste echar un vistazo al panorama americano). En Europa, ejemplos de ello lo tenemos en centros como el Archéodrome de Bourgogne, los de Beynac en Dordoña, o los de Lejre en Dinamarca (David, 1998, Chevillot, 1998, http://www.english.lejre-center.dk/, etc.).
Reconstrucción de una cabaña paleolítica: un modelo experimental del hábitat
Authors: Cuartero Felipe , Alonso Rodrigo , Terradill Marcos
Published: June 2023

Frecuentemente nos preguntamos sobre cuales fueron las diferentes estrategias de construcción empleadas por las sociedades paleolíticas para resguardarse de las inclemencias meteorológicas. Entre la historiografía clásica está muy extendido el tópico de que la humanidad en sus estadios más remotos es eminentemente 'cavernícola', incapaz en muchos casos, de construir sus propios refugios. Frente a esta visión determinista actualmente contamos con numerosos indicios que prueban la fabricación de estructuras habitacionales desde el Pleistoceno Medio como las documentadas en Soleihac (Bonifay et al., 1976), Terra Amata (Lumley, H. de, 1969b y 1976) y Lazaret (Lumley, H. de, 1969a), contando también con ejemplos en el Pleistoceno Inferior como las descubierta en Olduvai DK (Leakey, M. G. 1975), si bien es cierto estos últimos aún hoy en día siguen suscitando una gran controversia. ¿Estamos ante un problema de conservación de estas estructuras? ¿Realmente resulta tan complicado elaborar una cabaña confortable?.
Obsidiana y percutores: observaciones para explorar el registro arqueológico
Authors: Nami Hugo G.
Published: June 2023

Las obsidianas son vidrios volcánicos formados durante un rápido enfriamiento de ciertos tipos de lavas, generalmente con alto contenido silíceo (>65%). Puesto que en su mayoría son homogéneas e isotrópicas, como recurso natural, fueron ampliamente utilizadas por los artesanos del pasado en la confección de instrumentos líticos. Los talladores modernos también la tienen entre una de sus rocas preferidas (Whitakker 2004).Hay muchos grados y tipos con relación a sus cualidades de talla, carácter y color. Esas variaciones pueden ocurrir en las mismas fuentes. Las óptimas, en general poseen características muy similares; no obstante, algunas tienen sutiles diferencias lo cual motiva que para trabajarlas sean mejores que otras. Por ejemplo, la "obsidiana caoba" (mahogany obsidian) de Glass Butte (Oregon, EE. UU.) muestra ciertas obstáculos en la producción de delicados trabajos por presión puesto que por su estructura se producen cambios en las direcciones de la fuerza aplicada (obs. pers., Callahan com. pers. 2003).
Reproducción experimental del proceso de producción de cerámicas calcolíticas de la Extremadura portuguesa
Authors: De Carvalho Amaro Gonçalo , Anunciação Carlos
Published: June 2023

Muy sucintamente podemos definir la Extremadura portuguesa como la región que se encuentra delimitada, geográfica y geológicamente, al norte por el macizo de la Sierra de Aire y Candeeiros y al sur por la Sierra de Arrábida; al oeste por el Atlántico y al este por el valle del Tajo. Abarca tradicionalmente los distritos de Leiria, Lisboa y Setúbal (pudiendo también incluirse una pequeña parte del distrito de Santarém), agrupando prácticamente todo el litoral centro de Portugal