bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetically conditioned interaction among microRNA‐155, alpha‐klotho, and intra‐renal RAS in male rats: Link to CKD progression
Authors: Harrison‐Bernard L. M. , Raij L. , Tian R. X. , Jaimes E. A.
Published: October 2024

Incident chronic kidney disease (CKD) varies in populations with hypertension of similar severity. Proteinuria promotes CKD progression in part due to activation of plasminogen to plasmin in the podocytes, resulting in oxidative stress‐mediated injury. Additional mechanisms include deficiency of renal alpha‐klotho, that inhibits Wnt/beta‐catenin, an up regulator of intra‐renal renin angiotensin system (RAS) genes. Alpha‐klotho deficiency therefore results in upregulation of the intra‐renal RAS via Wnt/beta‐catenin. In hypertensive, Dahl salt sensitive (DS) and spontaneously hypertensive rats (SHR), we investigated renal and vascular injury, miR‐155, AT1R, alpha‐klotho, and TNF‐α. Hypertensive high salt DS (DS‐HS), but not SHR developed proteinuria, plasminuria, and glomerulosclerosis. Compared to DS low salt (DS‐LS), in hypertensive DS‐HS alpha‐klotho decreased 5‐fold in serum and 2.6‐fold in kidney, whereas serum mir‐155 decreased 3.3‐fold and AT1R increased 52% in kidney and 77% in aorta. AT1R, alpha‐klotho, and miR‐155 remained unchanged in prehypertensive and hypertensive SHR. TNF‐α increased by 3‐fold in serum and urine of DS‐HS rats. These studies unveiled in salt sensitive DS‐HS, but not in SHR, a genetically conditioned dysfunction of the intermolecular network integrated by alpha‐klotho, RAS, miR‐155, and TNF‐α that is at the helm of their end‐organ susceptibility while plasminuria may participate as a second hit.
False HbA1c value due to a rare variant of hemoglobin Petie Salpetriere coinherited with alpha thalassemia
Authors: Lepe Balsalobre Esperanza , Varo Sánchez Gema María , Rico Rodríguez Marta , Fuentes Cantero Sandra
Published: October 2024

Objectives

To describe a variant hemoglobin that interferes with HbA1c analysis by cation exchange HPLC.

Case presentation

A 78 years-old Spanish male patient visited the Internal Medicine Clinic for a routine check-up, with HbA1c included to screen for diabetes. He had suffered hypertension and dyslipidemia, and the patient had no previous symptoms suggestive of diabetes such as hyperglycemia, weight loss, polydipsia, polyuria or tiredness. Diabetes screening by HbA1c measurement was assessed using cation exchange HPLC and an immunoassay point-of-care analyzer. Routine hemoglobinopathy screening was performed including CBC, HbF and HbA2 measurement by cation exchange HPLC and capillary electrophoresis (CE). Further variant characterization was undertaken by DNA sequencing. Discordant HbA1c results were obtained for our subject, with elevated HbA1c of 52 mmol/mol measured by cation exchange HPLC and a normal level of 34 mmol/mol by immunoassay. Abnormal HbA1c peak shape prompted hemoglobinopathy screening to investigate potential variant interference. A globin gene analysis was performed, and the results showed a variant hemoglobin named ‘Hb Petie Salpetriere’. This variant arises from a Val → Phe substitution due to a mutation of c.103G>T of the beta-globin gene [BETA34 (B16) Val>Phe; HBB:c.103G>T].

Conclusions

This is the first reported case involving the Hb Petie Salpetriere variant in a Spanish patient. The present results show that the Hb Petie Salpetriere variant can affect the results of HbA1c analysis through ion-exchange HPLC, but not that obtained from the latex agglutination immunoassay. Only ion-exchange HPLC suggested the presence of the Hb variant in this case, suggesting that a careful review of the resulting chromatogram might reveal a potential variant.
Research on microscopic structure–activity relationship of AP particle–matrix interface in HTPB propellant
Authors: Zou Zijie , Qiang Hongfu , Zhou Junhong , Zhang Fengtao , Wang Xueren , Li Yiyi
Published: October 2024

The matrix and particle interface of hydroxyl-terminated polybutadiene (HTPB) propellant is the weakest part of its mechanical properties, making it prone to dewetting damage and destroying the structural integrity of the propellant. This article uses nano-indentation, gas cluster ion beam etching, and X-ray photoelectron spectroscopy experimental analyses to study the physicochemical properties of the interface and subsequently construct a microscopic model for the HTPB matrix and ammonium perchlorate particle interface. The model fully considers the existing forms of curing agent toluene diisocyanate, bonding agent Tris (2-methyl-aziridine) phosphine oxide (MAPO), and the aging products of the propellant in the interface structure. Meanwhile, the physicochemical properties, mechanical properties, and adhesive properties of the interface under different tensile loading conditions were analyzed. The results indicate that the bonding agent MAPO significantly enhances the mechanical and adhesive properties of the interface. The interface is sensitive to changes in temperature and tensile rate, and the aged interface is more fragile.
Formulation of Felodipine lipid nanoparticle-loaded oral fast-dissolving films
Authors: Naik Suparna Anand , DCruz Cleona Elizabeth Mary , Kumar Lalit , Shirodkar Rupesh Kalidas
Published: October 2024

Felodipine, a calcium channel blocker used to treat hypertension, is a BCS Class II drug characterized by low solubility, high permeability and significant hepatic metabolism, which limits its bioavailability to 15 %. This study focuses on improving the bioavailability of Felodipine by developing oral fast-dissolving films (OFDFs) incorporating lipid nanoparticles. Felodipine loaded lipid nanoparticles were prepared using glyceryl monooleate (GMO) as lipid and Poloxamer 407 as the surfactant, and then incorporated into OFDFs using the solvent casting technique. A Box-Behnken design with Design Expert Stat-Ease® 360 was used to evaluate the impact of GMO, Poloxamer 407 concentration, and sonication time on particle size and entrapment efficiency. The resulting nanoparticle dispersions had particle sizes ranging from 74.92 nm to 112.1 nm and entrapment efficiencies between 80.43 % and 95.23 %. Differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) confirmed successful drug encapsulation. The OFDF showed optimal mechanical properties, disintegration within (41.33 ± 3.51) s, and an in-vitro drug release of (89.82 ± 2.75) % in 6 min. Scanning electron microscopy (SEM) revealed a smooth, uniform, porous surface and the films remained stable for three months. The study concludes that Felodipine loaded lipid nanoparticles in fast-dissolving OFDFs improve permeability, dissolution, and onset of action, making them a promising approach for antihypertensive therapy.
Ownership Society of the Proletariat
Authors: Zhang Zhiyuan
Published: October 2024

One big puzzle in China’s market reform is how the government maintained popular support during the rapid socioeconomic transformation. This article argues that while the market transition aggravated economic inequality, the housing privatization reform of the late 1990s, in which public housing was sold at deeply discounted prices, provided a much-needed welfare benefit to the urban residents before a functioning welfare system was established. Using survey data collected in Beijing during the period of housing privatization reform, this study finds that urban residents who purchased public housing reported higher evaluations of China’s market reform and were more satisfied with government performance. The effect was stronger among SOE blue-collar workers, lower-income earners, and those without social insurance. Further analysis shows that the purchase of public housing had a long-lasting effect on shaping pro-market policy preferences among these former proletariats. These findings suggest that housing privatization contributed to a widely dispersed coalition that supported the government’s market-oriented policies, serving as a source of political legitimacy during the period of dramatic changes.
Quality of Life and Mental Development of Children with Acute Respiratory Infections Undergoing Hospital Treatment
Authors:   Yaroslavl State Medical University, Pavley Lyubov V. , Solodchuk Solodchuk ,   Yaroslavl State Medical University
Published: October 2024

Preserving the health of the younger generation is a priority multidisciplinary task. For a more comprehensive and individual assessment of the functioning of the child's body against the background of acute viral infections, a technique for determining the quality of life based on subjective perception was used, on the basis of which patients are classified into the first or second classes of quality of life. The paper examines the interrelationships of health, quality of life and mental development of preschool children with acute respiratory infections being treated in the pediatric department. Some children were found to have a reduced quality of life, not only in the group of children with acute respiratory infections, but also in the group of healthy children. There were significantly more patients with grade 2 quality of life in the main group. According to the results of correlation analysis using Spearmanʼs rank correlation coefficient, it was found that the quality of life is interrelated with psycho-emotional and the intellectual development of the child. Based on the study of the quality of life of patients in the pediatric department, it is possible to implement an individual approach to assessing the condition of the child as a whole and against the background of the disease, for high-quality further treatment and monitoring, for the organization of preventive measures.
The Implementation Of Discretionary Fixed Costs For Textile Waste Craftsman
Authors: Hidayah Retnoningrum , Suryarini Trisni , Suryandari Dhini , Kayati Ima Nur , Islamiatun Monita Bayu
Published: October 2024

Competition in the business world is an interesting thing to always observe. The rapid spread of micro, small, and medium enterprises (MSMEs) has led to high levels of competition. This service activity aims to provide an understanding regarding the calculation of discretionary fixed costs so that producers can calculate the desired profit level. The ability of MSME actors in this matter will be very beneficial for the development of their business. The target of this service activity is textile waste craftsmen who are in Menguneng Village, Pekalongan. Activities were carried out with the lecture method and practice calculations. Activities begin with initial coordination with partners to determine implementation time and equipment. Next, training was carried out in lectures and question and answer methods as well as calculation practice. Finally, monitoring and evaluation is carried out periodically. The results of the program show that the craftsmen understand the importance of calculating discretionary fixed costs for MSMEs. Furthermore, the craftsmen have been able to calculate the selling price of the product according to the profit target. Furthermore, it is hoped that there will be a positive synergy between the government and MSME craftsmen to increase product marketing.
Career Preparation Education for Students of Ahmad Yani Batang Islamic High School
Authors: Apriani Micki Ria , Setyawan Suprihono , Nuromavita Inka , Hidayati Arina , Sulistiyanto Tri Joko , Maranata Bonaventura Hendrawan
Published: October 2024

The implementation of community service for Ahmad Yani Islamic High School students, Batang District, Batang Regency, collaborated with one of the management lecturers at Karangturi University, Semarang. Ahmad Yani Batang Islamic High School is a private high school located in the village of Dracik Kembang, Proyonanggan sub-district, Batang district. This private school, established in 1985, is headed by Mr Mohammad Akyas, M.Sc. The future is uncertain. High school students who are less fortunate to continue their studies to the tertiary level will choose to work. However, there are so many high school students who, when they leave school, do not have sufficient provisions to face the world of work. Therefore, it is necessary to assist these students in providing an initial picture of strategies for entering the world of work.
Pelaksanaan pengabdian kepada masyarakat pada siswa SMA Islam Ahmad Yani Kecamatan Batang Kabupaten Batang berkolaborasi dengan salah satu dosen manajemen Universitas Karangturi Semarang. SMA Islam Ahmad Yani Batang adalah salah satu sekolah menengah swasta yang terletak di desa Dracik Kembang, kelurahan Proyonanggan kabupaten Batang. Sekolah swasta yang telah berdiri sejak tahun 1985 ini dikepalai oleh bapak Mohammad Akyas, M.Si. Masa depan adalah sesuatu hal yang tidak pasti. Para siswa SMA yang kurang beruntung untuk melanjutkan studi ke jenjang perguruan tinggi maka akan memilih untuk bekerja. Namun begitu banyak siswa SMA yang ketika lulus sekolah tidak memiliki bekal yang cukup untuk menghadapi dunia kerja. Oleh karena itu perlu untuk dilakukan pendampingan terhadap siswa-siswa tersebut guna memberikan gambaran awal mengenai strategi memasuki dunia kerja
Using Online-Based Learning Assessment Applications to Improve The Effectiveness of Distance Education
Authors: Siwi Menik Kurnia , Sofyan Rita , Kurniawati Tri
Published: October 2024

In each learning process, a teacher must carry out a learning assessment to measure students' ability to the learning given. For learning activities carried out online, a learning assessment is also needed for each of these online learning activities. This activity aims to improve the teacher's ability to apply various online assessment media. Activities were carried out in 8 meetings for training and delivery of material using the online assessment application. The activity results showed an increase in the teacher's ability to compose questions based on HOTs and Thematics. Apart from that, there has also been an increase in the knowledge and ability of teachers in making and operating online learning assessment applications.
Pada setiap proses pembelajaran, guru harus melakukan assessment pembelajaran untuk mengukur kemampuan peserta didik terhadap pembelajaran yang diberikan. Untuk kegiatan pembelajaran dilakukan secara online maka dibutuhkan pula assessment pembelajaran untuk setiap kegiatan pembelajaran online tersebut. Tujuan kegiatan ini adalah untuk meningkatkan kemampuan Guru dalam mengaplikasikan berbagai media assessment online. Kegiatan dilaksanakan dalam 8 kali pertemuan untuk pelatihan dan penyampaian materi penggunaan aplikasi assessment online. Hasil kegiatan menunjukkan adanya peningkatan kemampuan guru dalam menyusun soal berbasis HOTs dan Tematik. Selain itu juga terjadi peningkatan pengetahuan dan kemampuan guru dalam membuat dan mengoperasikan aplikasi assessment pembelajaran secara online.
Marketing Optimization Through Digital Advertising in “Kobamie Jaya” Cooperatives, Kendal District
Authors: Sehabuddin Ahmad , Widodo Joko , Murniawaty Indri
Published: October 2024

Business development is increasingly rapid and competition is getting sharper in capturing market share, companies are required to be able to empower their resources effectively and efficiently so that companies can have a competitive advantage. Kobamie Cooperative aims to prosper its members by expanding market share, especially in the use of digital media. However, in this case the Kobamie Cooperative has not been able to maximize its broad market share. In this case, the use of digital advertising has not been maximized. The solutions offered to overcome partner problems are training and assistance in strengthening marketing through digital advertising. The methods used in the community service include socialization activities, training, mentoring and evaluation of community service programs. The result of this community service is to increase partners' understanding of the concept of digital advertising, partners are able to practice, compose interesting content and images to be used as advertisements and partners are able to post advertisements via digital platforms. The conclusion of this community service is that this community service helps partners in marketing products via digital.
Perkembangan bisnis yang semakin pesat dan persaingan semakin tajam dalam merebut pangsa pasar, perusahaan dituntut untuk dapat memberdayakan sumber daya yang dimiliki secara efektif dan efisien agar perusahaan bisa mempunyai keunggulan bersaing. Koperasi Kobamie bertujuan untuk mensejahterakan anggotanya dengan memperluas pangsa pasar terutama dalam penggunaan media digital. Namun, dalam hal ini Koperasi Kobamie belum bisa secara maksimal meraih pangsa pasar yang luas. Dalam hal ini disebabkan karena penggunaan digital advertising yang belum maksimal dilakukan. Solusi yang ditawarkan untuk mengatasi permasalahan mitra yakni pelatihan dan pendampingan dalam penguatan pemasaran melalui digital advertising. Metode yang dilakukan dalam pengabdian meliputi kegiatan sosialisasi, pelatihan, pendampingan dan evaluasi program pengabdian.  Hasil dari pengabdian ini adalah meningkatkan pemahaman mitra tentang konsep digital advertising, mitra mampu mempraktekkan, menyusun konten dan gambar yang menarik untuk dijadikan iklan serta mitra mampu memposting iklan via platform digital. Kesimpulan dari pengabdian ini adalah dengan adanya pengabdian ini membantu mitra dalam memasarkan produk via digital.
Utilizing E-Commerce as An Effort to Increase the Economic Independence of Kopeng Tourism Village Communities
Authors: Suseno Deky Aji , Prajanti Sucihatiningsih Dian Wisika , Oktavilia Shanty , Putri Phany Ineke , Pratama Dafa Afif
Published: October 2024

Pandemi Covid-19 sampai dengan tahun 2021 masih berpengaruh bagi perekonomian masyarakat. Sektor pariwisata yang dinilai menimbulkan multiplier effect bagi perekonomian cukup besar turut lumpuh karena pembatasan mobilitas. Desa Wisata menjadi harapan besar bagi mitigasi pandemi, karena menggerakkan perekonomian masyarakat mulai dari wilayah administratif terkecil. Masyarakat desa, didorong untuk mampu mengakselerasi penggunaan teknologi sebagai faktor produksi untuk meningkatkan output /produk. Realita di lapangan menunjukkan bahwa belum semua pelaku usaha dan BUMDes menggunakan e-commerce dalam mempromosikan dan memasarkan hasil  usahanya. Kegiatan Pengabdian kepada masyarakat ini, bertujuan untuk menberikan recharging dan pembekalan teknologi untuk meningkatkan penjualan produk desa wisata melalui e-commerce. Khalayak sasaran dalam kegiatan ini adalah pelaku UMKM dan pengelola BUMDes di Desa Kopeng Kecamatan Getasan. Metode kegiatan pengabdian kepada masyarakat menggunakan ceramah, praktik dan pendampingan. Pertama peserta akan diberikan ceramah mengenai e-commerce. Selanjutnya peserta akan praktik memanfaatkan e-commerce. Hasil kegiatan pengabdian kepada masyarakat menunjukkan adanya peningkatan pemahaman dan penggunaan terhadap e-commerce.
The Covid-19 pandemic until 2021 will still affect the community's economy. The tourism sector, which is considered to have a significant multiplier effect on the economy, is also paralyzed due to restrictions on mobility. Tourism villages are a big hope for pandemic mitigation because they move the community's economy from the smallest administrative area. Village communities are encouraged to be able to accelerate the use of technology as a factor of production to increase output/product. The reality in the field shows that not all business actors and BUMDes use e-commerce to promote and market their business results. This community service activity aims to provide recharging and technology supplies to increase sales of tourist village products through e-commerce. The target audience in this activity is SME actors and BUMDes managers in Kopeng Village, Getasan District. The method of community service activities uses lectures, practices and mentoring. First, participants will be given a lecture about e-commerce. Furthermore, participants will practice using e-commerce. The results of community service activities show increased understanding and use of e-commerce.
Case Method: Strategy For Improving The Capability Of Developing Teaching Modules Towards Differentiation Learning
Authors: Jarot Tri Bowo Santoso  , Margunani  , Moch Faizal Rachmadi  , Muhammad Dwilian Fathurrohman  , Naim Devitrisia
Published: October 2024

The Ministry of Education, Culture, Research, and Technology of the Republic of Indonesia continues to strive for renewal and adaptation, including in the field of education. One way is by Implementing the Independent Curriculum (IKM). The IKM is an effort to catch up on learning losses due to the COVID-19 pandemic by returning school and local government authorities to manage their own education in accordance with conditions in their area. Even so, there are still many obstacles and confusion, especially for teachers in preparing for the learning process, one of which is in the education unit area of Semarang Regency. Teachers still do not optimally know the Learning Outcomes (CP), the formulation of Learning Objectives (TP), the preparation of Learning Objectives Flow (ATP) from Learning Objectives (TP), and the design of Teaching Modules. This service focuses on preparing differentiated teaching modules as a form of IKM acceleration. The method used is to conduct a workshop on preparing differentiated teaching modules based on the case method, followed by assistance in pre- and post-activity and program evaluation monitoring. This program targets partners, namely economics teachers, who are members of the Economics Subject Teacher Consultation (MGMP) throughout Semarang Regency. The results of this activity showed that teachers were very interested and able to improve the skills and understanding of teachers in preparing differentiated modules. The suggestion for this activity is that the relevant agencies always provide training in preparing differentiated teaching modules until all teachers follow, and in the future, it is hoped that the relevant parties and many universities will carry out evaluation training in the independent curriculum.
Findings from a public engagement programme for school children aged 13–15 years about endocrinology
Authors: Ali Baig Shams , Malhotra Kashish , Kowsik Mukunth , Banerjee Josh , Rahman Fazna , Ashokkumar Ashmethaa , Gillett Caroline , Kempegowda Punith
Published: October 2024

Objectives

To investigate the utility and effectiveness of a school outreach programme in areas of lower socioeconomic status to improve understanding of common endocrine topics and the medical profession.

Methods

Two secondary school outreach sessions were conducted in July 2022. Students were invited to attend lectures delivered by medical professionals and engage in poster-making sessions using the knowledge they had gained throughout the day. Participants completed anonymised pre- and post-session surveys. Outcomes were identified using Kirkpatrick’s training evaluation model. Self-reported perceptions and beliefs (Kirkpatrick’s level 2a) were compared using chi-square tests. Thematic analysis of team-led poster presentations was performed.

Results

Of the 254 participants included, the response rates of pre- and post-session questionnaires were 75.6% and 56.2%, respectively. The outreach day increased students’ understanding of obesity and diabetes, polycystic ovary syndrome, and Health Technology. The most well-received activities from the outreach day were voted to be the poster challenge (43.4%) and poster presentation (14.7%). Following the session, there was a trend towards an increased understanding of medical careers and interest in pursuing a medical career, although these did not reach statistical significance.

Conclusions

Outreach programmes could be a practical and effective approach to engaging prospective medical applicants from areas of lower socioeconomic status. Further studies are required to expand outreach programmes and investigate the efficacy of school engagement programmes.
Oncostatin M: friend or foe in PCOS pathogenesis?
Authors: Nikanfar Saba , Oghbaei Farnaz , Nejabati Hamid R , Zarezadeh Reza , Latifi Zeinab , Laleh Sanya Hayati , Khodavirdilou lida , Khodavirdilou Rasa , Amorim Christiani A , Fattahi Amir
Published: October 2024

Polycystic ovary syndrome (PCOS) is a primary endocrinological disorder in women of reproductive age that is characterized by androgen excess and ovulatory irregularities. This syndrome is associated with adipose tissue dysfunction, an elevated risk of insulin resistance, hyperinsulinemia, obesity, and type 2 diabetes. Adipocyte dysfunction affects the secretion of adipokines and pro-inflammatory cytokines. Nevertheless, adipose tissue is not an exclusive source of adipokines as it can also be produced locally by reproductive tissues. Although adipokines have been recognized in the development of PCOS, the role of oncostatin M (OSM), a multifaceted adipokine, remains unclear. Current evidence suggests that this cytokine is associated with key aspects of the syndrome, including obesity, insulin resistance, hyperandrogenism, and inflammation. However, the data are often contradictory, likely due to variations in study designs, methodologies, and species differences. By investigating the link between OSM and PCOS-associated issues, this review identified the potential role of this adipokine in PCOS pathogenesis. This underscores the need for further research to clarify its predominant effects and assess its relevance as a therapeutic target.
The gut microbiome without any plant food? A case study on the gut microbiome of a healthy carnivore
Authors: Karačić Andrija , Dikarlo Plamena , Dorst Isabel , Renko Ira , Liberati Pršo Ana-Marija
Published: October 2024

Objective

The carnivore diet is a ketogenic diet based exclusively on the consumption of food of animal origin. While the impact of various diets on the gut microbiome is extensively documented, the effects of a carnivore diet remain unclear. To address this gap, we conducted a pilot study on the gut microbiome of an individual following a carnivore diet and compared it with that of a subgroup of healthy individuals.

Methods

A stool sample was collected from a healthy 32-year-old male adhering to a carnivore diet and was sequenced using 16S DNA Amplicon Sequencing. The results were then compared to those from three control groups possessing similar anthropometric characteristics and differing in their frequency of meat consumption.

Results

The gut microbiome of the carnivore was dominated by the phylum Firmicutes and the genera Faecalibacterium, Blautia, unspecific Lachnospiraceae, Bacteroides, and Roseburia—bacteria known for fiber degradation. Furthermore, neither alpha- nor beta-diversity, nor the functional capacity of the gut microbiome, showed differences when compared to the control groups. Additionally, the gut microbiome of the carnivore showed the least similarities with the microbiome of the cohort consuming meat on a daily basis.

Conclusion

In our study, we showcase the compositional and functional characteristics of the gut microbiome in an individual on a carnivorous diet, finding no differences in comparison to a control cohort. Further research is needed to investigate the short- and long-term impacts of a carnivorous diet on gut health through cross-sectional and longitudinal studies.

Significance statement

To the best of our knowledge, this is the first study to report on the composition of the gut microbiome of a person adhering long-term to the carnivore diet.
Multicriteria Optimization of Stochastic Robust Control of the Tracking System
Authors:   Anatolii Pidhornyi Institute of Power Machines and Systems of NAS of Ukraine, Kuznetsov Borys I. , Bovdui Ihor V. ,   Anatolii Pidhornyi Institute of Power Machines and Systems of NAS of Ukraine, Voloshko Olena V. ,   Anatolii Pidhornyi Institute of Power Machines and Systems of NAS of Ukraine, Nikitina Tetyana B. ,   Bakhmut Education Research and Professional Pedagogical Institute of V. N. Karazin Kharkiv National University, Kobylianskyi Borys B. ,   Bakhmut Education Research and Professional Pedagogical Institute of V. N. Karazin Kharkiv National University
Published: October 2024

A multicriteria optimization of stochastic robust control with two degrees of freedom of a tracking system with anisotropic regulators has been developed to increase accuracy and reduce sensitivity to uncertain object parameters. Such objects are located on a moving base, on which sensors for angles, angular velocities and angular accelerations are installed. Improvements in the accuracy of control with two degrees of freedom include closed-loop feedback control and open-loop feedback control through the use of reference and perturbation effects. The multicriteria optimization of the stochastic robust control tracking system with two degrees of freedom with anisotropic controllers is reduced to the iterative solution of a system of four coupled Riccati equations, the Lyapunov equation, and the determination of the anisotropy norm of the system by an expression of a special form, which is numerically solved using the homotopy method, which includes vectorization matrices and iterations according to Newton's method. The objective vector of robust control is calculated in the form of a solution of a vector game, the vector gains of which are direct indicators of the quality that the system should achieve in different modes of its operation. The calculation of the vector gains of this game is related to the simulation of a synthesized system with anisotropic regulators for different modes of operation with different input signals and object parameter values. The solutions of this vector game are calculated on the basis of a set of Pareto-optimal solutions taking into account the binary relations of preferences on the basis of the metaheuristic algorithm of multi-swarm Archimedes optimization. Based on the results of the synthesis of stochastic robust control of a tracking system with two degrees of freedom with anisotropic controllers, it is shown that the use of synthesized controllers made it possible to increase the accuracy of system control, reduce the time of transient processes by 3–5 times, reduce the variance of errors by 2.7 times, and reduce the sensitivity of the system to the change of object parameters compared to typical regulators.
Selection of optimal areas for the installation of Wind Farms in the north-eastern part of Cuba
Authors: Infante-Haynes Ángel Eugenio , Hernández-Ramírez Gabriel , Castillo-Pantoja Hiovanis , Vázquez-Gómez María Dolores
Published: October 2024

The present research aims to select optimal areas for the installation of wind farms in the north-eastern part of Cuba. The research is based on the free software QGIS, Hierarchical Process Analysis, databases of the information of the alternatives and criteria and Geographic Information Systems (GIS), which makes it possible to know the places where these farms will be installed. In addition, experts were consulted to obtain the weights or level of importance of the selected criteria, such as distance to ports, distances to common roads, distances to population centers, to electrical grids and finally the wind speed. As a result, a mathematical conceptual model was obtained for the selection of optimal zones for the installation of wind farms in the eastern north of Cuba, by means of the MCDM and GIS methods, where it was determined that, within the evaluated alternatives of wind farms, Gibara III is the optimal one. These models will allow the development of wind projects in the eastern region of Holguin, and to be able to manage human, financial and material resources.
Identification of short term Fast-Slow patterns using the Nasdaq-100 future through a technical analysis application
Authors: Montes-Gómez Luis Fernando , Gúzman-Aguilar Diana Sirley , Pinzon-Sanchez Luis Alberto
Published: October 2024

In recent decades, the analysis of atypical behavior in asset prices has become relevant, since participants in financial markets recognize that the idea of perfect markets is distanced from reality. The purpose of this research is to present a trading strategy through the identification of short-term chart patterns, based on anomalies in the future price of the Nasdaq-100 index. The historical backtesting methodology will be used in the technical analysis of the asset to quantify the performance of the identified patterns. It will be verified that the anomalies in the stock index are not temporary; rather, they persist and recur on a recurring basis, especially in intraday events. Additionally, the best performing trading session will be determined. This work will provide retail traders with trading guidelines to approach the markets with a statistically profitable strategy.
Structural equations modelling applied to the study of Communities Supported Agriculture (CSAs) located in the Southeastern region of Brazil
Authors: Alves de Melo Gustavo , De Castro Júnior Luiz Gonzaga , Gomes Carvalho Eduardo , Mendonça Peixoto Maria Gabriela , Borges Barbosa Samuel , Guarnieri dos Santos Patrícia , Marques Serrano André Luiz , Gomes Ferreira Lucas Oliveira , Guerra José Baltazar Salgueirinho Osório de Andrade
Published: October 2024

Food production is an increasingly relevant issue in the current framework associated with food and water security and future years projections. In addition, the production of organic food has gained significance in recent years, revealing a growing change in the population's consumption habits. The Communities Supported Agriculture (CSAs) play an important role in enabling productive areas for planting crops in agroecological and biodynamic standards. Given this, this study aimed to investigate the relationship between different CSAs variables located in the Southeastern region of Brazil to validate or not the hypotheses created. Thus, the study was designed as a descriptive research and quantitative approach, using an inductive logic survey. In addition, the methodology was set up with the support of the Structural Equation Modeling technique. The study confirmed the hypothesis (H1) that socioeconomic characteristics positively influence CSAs’ performance. The limitations were associated with the method of data collection and the difficulties imposed by the Covid-19 pandemic.
Analysis of the scientific production on the implementation of knowledge management for supply chain sustainability
Authors: Domínguez-Díaz Leonardo Ernesto , Sánchez-Suárez Yasniel , Marqués-León Maylín , Hernández-Nariño Arialys
Published: October 2024

This research aims to analyze the scientific production on the implementation of knowledge management for sustainability of supply chain. The study is of a descriptive quantitative type, by performing a bibliometric analysis executed in the Scopus database where only the articles found in open access in the areas of engineering, business, administration and accounting sciences were considered. A total of 43 articles were detected. The authors with the major contributions were Tseng, M.L. and Mangla, S.K. The most productive institutions were Brunel University London and Brunel Business School. The country in which the largest number of research papers were published was The United Kingdom. The articles were published in 29 journals. A bibliometric map of co-authorship was carried out, which showed that these were grouped into four clusters and that of co-occurrence of keywords structured into six clusters, which identified six lines of research.
Documentary analysis on productivity in enterprises
Authors: Santillan-Valdelamar Maria Guadalupe , Dimas-Díaz Francelin , Martínez-Corona José Isaías , Palacios-Almón Gloria Edith
Published: October 2024

Productivity is a key indicator for the sustainable growth of enterprises. However, small and medium-sized enterprises (SMEs) often do not measure it; therefore, there is a need to develop a greater understanding of this concept as a subject of study. A study was conducted with a qualitative approach using a documentary analysis technique based on a documentary record instrument. The research objective is to locate, analyze, and synthesize scientific evidence on business productivity to strengthen the theoretical and methodological foundations for further analysis and application in future studies. The results are presented in the following categories: Productivity concepts, efficiency, effectiveness, and competitiveness; variables or factors affecting productivity; productivity techniques and tools; case studies on productivity; and productivity and human talent. The findings of this research can contribute to promoting the measurement of productivity in SMEs.
Por uma visão dialógica do conceito de “escrevivência”, de Conceição Evaristo
Authors: Machado da Rosa Kelli
Published: October 2024

Neste artigo, buscamos compreender, dialogicamente, o termo “escrevivência” proposto pela pesquisadora e escritora brasileira Conceição Evaristo, aprofundando a discussão do conceito por meio da análise dialógica do romance Becos da memória (2018). Nossas reflexões se edificam em dois eixos analíticos: a) escrevivência como ato de resistência e as reverberações dessa escrita de si na construção discursiva das personagens do romance; b) escrevivência como lugar de confluência do heterodiscurso dialogizado e os tons de denúncia refletidos e refratados no discurso do romance em foco. Por meio das análises, é possível vislumbrar a escrita de si como lugar de (re)construção de memórias, como ato, como existir no mundo. A favela, nesse sentido, ganha corpo, voz e sentidos: através dos fatos em quebra-cabeças, dialogicamente guiados pela narradora, o leitor capta o jogo de forças sociais que sustenta a ambiência da favela. Valores sociais e subjetivos como o amor, o ódio, a solidariedade, a violência, a amizade, a sobrevivência individual e coletiva emergem dessa escrita, produzindo resistência na sociedade contemporânea.
Akissi
Authors: dos Santos Rodrigues Márcio
Published: October 2024

Este estudo investiga as representações da infância na série de quadrinhos Akissi, da marfinense Marguerite Abouet e do francês Mathieu Sapin. A série narra, com um forte tom humorístico, as travessuras e aventuras de uma menina chamada Akissi, que reside em um cenário urbano de Abidjan, a maior cidade e centro econômico da Costa do Marfim. A análise problematiza a questão das figurações em torno de criança fora dos moldes ocidentais, discutindo como as vivências infantis africanas são moldadas por contextos culturais e sociais específicos. O artigo também foca nas interações sociais, brincadeiras e dinâmicas comunitárias locais, de modo a refletir sobre as diversas maneiras pelas quais a infância é experienciada em um contexto africano, contrapondo-se às narrativas frequentemente encontradas na produção cultural ocidental.
A létfontosságú rendszerelemek és a technológiai fejlődés új kockázatai (II. rész)
Authors: Horváth Attila
Published: October 2024

A tanulmány az utóbbi évtizedekben megváltozott felfogások alapján áttekinti a biztonságot veszélyeztető kockázati tényezőket. A szerző korábbi kutatásaira alapozva és az újabb kutatási eredményeként a tanulmány részletesen elemzi a kritikus infrastruktúrák (létfontosságú rendszerelemek) működésével kapcsolatos veszélyeket. A létfontosságú rendszerelemek kölcsönhatásainak vizsgálatával bizonyítja egy átfogó biztonsági szemlélet elterjesztésének szükségességét. A szerző új típusú biztonsági kockázatok közül a mesterséges intelligenciák társadalmi, katonai és etikai kockázatait vizsgálja.
Reguláris fegyveres erők elnyomó tevékenysége társadalmi zavargásokkal szemben : Néhány gondolat a hadtörténeti példák alapján
Authors: Solymos András
Published: October 2024

A szerző azt a sajátos helyzetet vizsgálja, amikor reguláris hadseregek folytatnak fegyveres küzdelmet olyan irreguláris fegyveres erőkkel, amelyek társadalmi-politikai céljaikat fegyveres harc útján kívánják elérni. Napjainkban az aszimmetrikus háborúk problémái azért kerültek előtérbe, mert a katonai pusztító képességek megnövekedésével a totális háború céltalan. Viszont egyes régiókban a meglévő társadalmi, etnikai, vallási ellentétek átmehetnek fegyveres harcba – megfelelő külső támogatás mellett, amelyet viszont a regionális vagy globális nagyhatalmak, politikai erők képesek is biztosítani saját céljaik elérése érdekében. A szerző azokat a feltételeket elemzi, amelyek ilyen sajátos körülmények között lehetővé teszik a reguláris erők sikerét.
A Száhel-övezet válsága
Authors: Varga Márton
Published: October 2024

A Száhel-övezet egy olyan összetett válságzóna, mely jelentős kihívás elé állítja az érintett országokat és a nemzetközi közösséget egyaránt. Az egymásba fonódó, mélyen gyökerező problémák a világ egyik legveszélyeztetettebb régiójává teszik ezt a térséget. Bár a Száhel-övezet országai önmaguk is súlyos problémáktól szenvednek, a valós eredmények elérésének érdekében a megoldást regionális szinten kell keresni. E cikkben a válság okait és a lehetséges megoldásokat kívánom bemutatni.
A vezetés automatizálásának alapelvei és első eredményei a szovjet fegyveres erőknél (II.)
Authors: Négyesi Imre
Published: October 2024

Ebben a cikkben bemutatásra és elemzésre kerülnek a vezetés automatizálásának első szovjet eredményei és ehhez kapcsolódóan a katonai feladatok automatizált végrehajtásának kezdeti lépései.
Stratégiai kérdések, stratégiai válaszok (Recenzió Davutoğlu, Ahmet: Stratégiai mélység, Törökország nemzetközi helyzete című könyvéről)
Authors: Siposné Kecskeméthy Klára
Published: October 2024

Ahmet Davutoğlu török miniszterelnök Stratégiai mélység ‒ Törökország nemzetközi helyzete című könyve1 jelent meg Magyarországon, az Antall József Tudásközpont (Tudásközpont) gondozásában. Davutoğlu könyve a Tudásközpont színvonalas kiadványai sorába illeszkedik.
Szerethetők-e a robotok
Authors: Kollár Csaba
Published: October 2024

Bizonyára sokan fel tudunk idézni olyan filmélményt, amelyben olyan robotok voltak a főszereplők, amelyek kedvelhetők, szerethetők voltak, esetleg a néző a robot szerepével még azonosulni is tudott. Számos olyan fejlesztésnek vagyunk a szemtanúi (például EveR, DER2, Saya, Sophia, Jangjang), amelyiknél az elsődleges cél olyan robotok megalkotása, amelyek alapvetően az emberre minél jobban hasonlító androidok, humanoidok. Ez igaz többek között antropometriai jellemzõikre, mimikájukra, gesztusaikra, hangjukra. Jelen tanulmány azember érzékszervei (esetünkben látás, hallás, tapintás) útján érzékelhető, hagyományos és kiterjesztett/virtuális külvilágban jelen levő, embernek tűnő robotmegjelenésekkel és megnyilvánulásokkal foglalkozik. Kommunikációs aspektusból elsősorban azt vizsgálja, hogy milyen lehet, mitől függhet az ember–robot kapcsolat, kialakulhatnak-e emberi érzelmek, ezek, illetve a kapcsolat elmélyülhet-e. Tanulmányom első részében teoretikus, második részében pedig empirikus források, ez utóbbinál saját kutatás segítségével is vizsgálom a témát.
A 16. Robothadviselés szakmai tudományos konferenciáról
Authors: Ványa László
Published: October 2024

2016. november 24-én, a hagyományoknak megfelelően, november utolsó csütörtöki napján került megrendezésre a Robothadviselés 2016 szakmai tudományos konferencia az Nemzeti Közszolgálati Egyetem (NKE) Hadtudományi és Honvédtisztképző Kar (HHK) Dísztermében. Szervezője a HHK Katonai Üzemeltető Intézet (KÜI) Elektronikai Hadviselés Tanszéke és a Magyar Hadtudományi Társaság (MHTT) Elektronikai, Informatikai és Robotikai Szakosztálya volt. Az idén is több mint 130 szakember és a robotika iránt érdeklődő vendég látogatta meg a rendezvényt.
Humánerőforrások és a technikai, technológiai fejlődés kihívásai a menedzsment-paradigmák tükrében
Authors: Poór József
Published: October 2024

A Humán Szakemberek Országos Szövetsége több éve együttműködik a Magyar Hadtudományi Társasággal. Két évvel ezelőtt volt egy közös konferenciánk. Sokat töprengtem azon, hogy vajon civilként mit is mondhatnék a nem civilek számára. Régóta foglalkozom a vezetéssel (manapság úgy hívják, hogy menedzsment-tudomány), ezért úgy gondoltam, hogy néhány általános paradigmát mondanék el. Ezzel összefüggésben kitérnék arra, hogy szükséges vagy sem a paradigmaváltás a menedzsment területén.
A humán erőforrás és a fejlett technika és technológia viszonya a honvédségben
Authors: Törő Lajos
Published: October 2024

A hozzászólás gondolatmenete: A témakör létjogosultsága – A hivatások felértékelődésének okai – A katonai hivatás speciális értekei és elemei – A katonai hivatás és a vallás viszonya – A katonai etika, tiszti értékrend az oktatásban.
Hivatástudat és technológiai fejlődés a Magyar Honvédségben
Authors: Benkő Tibor
Published: October 2024

A Magyar Hadtudományi Társaság, mint civil szervezet ugyan nem a Magyar Honvédség része, azonban tevékenysége és céljai által ezer szállal kötődnek ahhoz. A Magyar Honvédség számára rendkívül fontos a tudományos élet, ezért örömömre szolgál, hogy a Magyar Hadtudományi Társaság konferenciájának a Humánerőforrások és a technikai, technológiai fejlődés kihívásai a honvédségben címet választották. A honvédelem szempontjából a tudomány, az innováció elengedhetetlen, ezért a Honvéd Vezérkar tudományos életének a felpezsdítésére 2013-ban létrehoztuk a Honvéd Vezérkar Tudományos Kutatóhelyet, melynek főbb feladatai – többek között – a tudományos munka szervezése, kutatások végzése, a kutatási eredmények támogatása. A konferencia céljának megfelelően az előadásomban a katonai hivatástudatról, a technológiai fejlődésről, a jövőbeni perspektívákról és pár aktuális szervezeti változásról fogok szólni.
A parancsnoki szerepkör és a csapatépítés felelőssége, kihívások a (poszt)modern haderőben
Authors: Takács Attila Géza
Published: October 2024

Jelen tanulmányomban a kutatási eredményeim és saját tapasztalataim megosztásával szeretném bemutatni a parancsnoki szerepkört, és azokat a kihívásokat, amelyek aktuálisan jelen vannak a Magyar Honvédség mindennapjaiban. A parancsnoknak mindig figyelembe kell vennie a külső és belső környezeti változásokat. A hadviselés, a háború megvívásának módja átalakult az elmúlt negyedszázad során. Az egyes események elemzésével, majd az eredmények közötti összefüggések megállapításával olyan következtetésekre juthatunk, amelyek megalapozhatják a következő feladatra való felkészülést és javíthatja az alárendeltek helyzetfelismerő képességét.
NATO-csúcstalálkozó az elrettentés és a védelem jegyében (Varsó, 2016. július 8–9.)
Authors: Siposné Kecskeméthy Klára
Published: October 2024

Az egységes, erős, felkészült és alkalmazkodó NATO kulcsfontosságú célkitűzés. A Varsói Csúcsértekezlet kiemelten fontos volt a kollektív védelem irányába forduló NATO programjának megvalósításához. A tanulmány áttekinti a NATO védelmi képesség növelésére irányuló kezdeményezéseit, az elmúlt évtizedek védelmi költségvetés alakulásának trendjeit. A csúcsértekezleten a katonai képességekkel és műveletekkel, a Szövetség keleti és déli határain jelentkező veszélyekkel és a határok védelmével, a NATO–Oroszország viszonnyal, kiemelten foglalkoztak.
Társadalmi biztonság a terrorizmus árnyékában
Authors: Varga Márton
Published: October 2024

Az elmúlt évtizedekben a megváltozott terrorizmus hatására egyes terrorista szervezetek globális befolyásúvá váltak. E szervezetek a lokális problémákra építve, a helyi lakosok kihasználásával alakítják ki hálózatukat. Az olyan összetett válságrégiók, mint például a Száhel-övezet, rendkívül kiszolgáltatottak a különféle radikális szervezetek terjeszkedésének. E cikkben a civilek lehetséges szerepét kívánom bemutatni a terrorizmus ellen vívott küzdelemben.
A tábori automatizált csapatvezetési rendszer története - 2. rész
Authors: Négyesi Imre
Published: October 2024

A cikk első részének tárgya a Varsói Szerződés keretein belül a szárazföldi katonai feladatok automatizálásának egy újabb eredménye, a létrehozás történeti előzményeitől a fejlesztés kezdetéig. A második rész a tábori automatizált csapatvezetési rendszer megvalósításának kezdeti lépéseivel és a továbbfejlesztés irányainak lehetőségeivel, kérdéseivel foglalkozik.