bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of the formation of interpersonal relationships in primary school students in an inclusive education
Authors: Dzheiranova Sofia Dionisievna , Kolesnikov Ilya Nikolaevich , Kuzmina Anna Bronislavovna
Published: June 2020

The results of an empiric study of the characteristics of interpersonal relationships in an inclusive environment in primary school children with normal and impaired development are presented in the article. The authors describe the features of the correctional development work, the methods and techniques used; features of theatrical and design activities application to optimize interpersonal relationships in an inclusive environment are considered. Based on the results of the study, the recommendations for teachers on the studied issues are proposed by the authors.
The Young Teacher Preparing to Work With Gifted Children in the Continuing Education System
Authors: Khalikova Fidaliya Damirovna
Published: June 2020

The article is devoted to the preparation of young teachers to work with gifted children in the system of continuing education. The author outlines that activity of a young teacher with gifted children is a very responsible job that constantly requires the teacher to master professional skills, develop personal qualities, flexibility, emotional stability, and the ability to create individual and personalized programs designed for all types of pupils, including gifted children. The author comes to the conclusion that preparation of young teachers to work with smart and gifted children should be focused on improve their theoretical knowledge on the specifics of a gifted child’s psychology , as well as on the formation of professionally important qualities necessary to ensure the effectiveness of the educational process, which contributes to the improvement of skills, increase the general and psychological and pedagogical culture of a young teacher for the development of professional competence and ownership of the professional component in the system of continuing education.
Seismological Monitoring in Latvia
Authors: Ņikuļins Valerijs G
Published: June 2020

Valerijs G. Ņikuļins reports on  seismological monitoring in Latvia for the Summary of the Bulletin of the ISC.
Modeling a pneumohydraulic sprayer for irrigation and fertigation
Authors: Gorobej V. P , Moskalevich V. Y.U
Published: June 2020

The aim of the research was to increase the efficiency of use and the ability to control liquid spraying when creating artificial rain in medium to reduce energy consumption, to increase the reliability of the device for irrigation of crops, which combines additional processing of plants with various technologies for growing them by creating the necessary conditions for the formation of a water-air stream due to substantiation of the structural and geometric design parameters of sprayer. The most common irrigation method called the sprinkling is analyzed. The need to increase the economic efficiency of spray nozzle designs to improve the quality of artificial rain is shown. A fundamentally new scheme of the spraying device for innovative irrigation technologies and a mathematical model for the theoretical and technological substantiation of its main parameters: the diameters of the nozzles of the water and air nozzles, the diameter and length of the mixing chamber, as well as the necessary water and air pressures, are developed. The rationale for the design decisions of the pneumohydraulic sprayer is given. The destruction of the continuity of the liquid in the atomizer is considered taking into account the parameter of its strength during the interaction of heterogeneous phases of water and air. In this case, the air supply for spraying the liquid can be carried out either by force or by ejection. The algorithm for calculating the parameters of the spraying device is executed and works in a spreadsheet (EXCEL or WPS) using the mathematical expressions justified for the main structural and technological parameters of the device. The initial data are the pressure of water р1 and air р2 at the inlet of the sprayer, the required water flow rate G1 and the ejection coefficient u. The calculations take into account the flow coefficients of water and air µ, the gas constant R and the air temperature Т. The calculation results are displayed in EXCEL tables. Based on the results of mathematical modeling of the operation of the pneumohydraulic sprayer there were obtained the graphical dependencies to optimize its technological parameters and design solutions for the development, manufacture of a pneumohydraulic sprayer prototype and its experimental testing to obtain droplets of artificial rain of various sizes during irrigation and fertigation of crops, which will contribute to a successful solution of discussed agroindustrial complex problems.
The method for determining the amount of interference formed during the assembly of the rim and disk of the wheel of automobile and tractor
Authors: Maksimov E. A , Ustinovsky E. P
Published: June 2020

The disk-rim system is a complex structure with a variety of properties that have not yet been fully studied. The vehicle wheel is an axisymmetric structure consisting of a rim and a disk for attaching it to the hub. On the one hand, the outer diameter of the disk (flange) is welded around the circumference to the inner diameter of the rim (shelf), forming a rigid one-piece connection. On the other hand, using a bolted connection, the disk is attached to the hub, forming a wheel-hub assembly. The assembly line of the rim and wheel disk of a truck consists of the following technological operations: pressing the disk into the rim, welding the outer seam, welding the inner seam, cleaning the surface from welding spatter, punching the valve hole, curing burrs on the valve hole, and controlling the runout. When pressing the disk into the rim, it is necessary to know the amount of interference, as well as the distribution of radial and tangential stresses. Determining the amount of interference is an urgent task, since this characteristic is fundamental when assembling the rim and wheel disc. It was found that for radial stresses the compression is observed. Its largest value is located at the boundary of the disk and the rim. For tangential stresses the tension is observed. Its largest value is located at the boundary of the disk and the rim. Calculations showed that for a 400 mm wheel disk, a 300 mm wheel rim an elastic modulus is 2∙104 MPa, a force modulus is 600 MPa, an interference fit is 0,0865 mm.
The study of the technological process of the operation of the stalk lifter when mowing down dead grain and leguminous crops
Authors: Primak V. N , Popov A. Y.U
Published: June 2020

Nowadays, the roller reapers and headers of grain harvesters, when mowing down dead grain and leguminous crops, are equipped with stalk lifts. The successful completion of the process of raising flat and cut stems depends on the correct choice of the angle of inclination of the wing of the stem lift. In existing designs of stalk lifts, the angle of inclination is set less than the angle of friction of the stalk on the surface of the device. However, with this approach to choosing an angle with a moist stalk and large fluctuations in the microrelief of the field surface, there are observed the enveloping of the wings of the stalk lifters and the process of unloading of the grain mass. This suggests that knowledge of the coefficient of friction of the stems of harvested crops in the design of stem lifters is not enough. Therefore, there is a need to study the process of lifting the stems of grain and leguminous crops. The aim of the study is to determine the theoretical dependence of the magnitude of the rise of the stems on the structural and technological parameters of the operation of the stemlifting device of harvesting machines when mowing dead grains and legumes, as well as the technological properties of the harvested crop. The article discusses the process of lifting a cut stem along the surface of the stem lifter, as well as a laden uncut stem, taking into account the strength of resistance to bending and weaving of the stems. The forces acting on the stem are determined. The assumption is made about the absolute inelasticity of the impact of the stem on the surface of the device. Based on the obtained mathematical model, graphs of theoretical dependencies of the maximum possible movement of the stem and the height of its rise depending on the speed of the machine and the angle of installation of the wing of the stem lifter are constructed. Analysis of the obtained dependences allows us to conclude that the design parameters of the stem lifter are determined both by the sliding friction coefficient of the stems of harvested crops and by the speed of the harvester and the strength of the bending resistance of the stem as well.
Initial Physician Experience with [18F]Flutemetamol Amyloid PET Imaging Following Availability for Routine Clinical Use in Japan
Authors: Hattori Naoya , Sherwin Paul , Farrar Gill
Published: June 2020

Background:

Brain amyloid is a neuropathological hallmark of Alzheimer’s disease (AD). By visualizing brain amyloid, positron emission tomography (PET) may influence the diagnostic assessment and management of patients with cognitive impairment.

Objective:

As part of a Japanese post-approval study to measure the safety of [18F]flutemetamol PET, the association of amyloid PET results with changes in diagnosis and diagnostic confidence was assessed.

Methods:

Fifty-seven subjects were imaged for amyloid PET using [18F]flutemetamol at a single Japanese memory clinic. The cognitive diagnosis and referring physician’s confidence in the diagnosis were recorded before and after availability of PET results. Imaging started approximately 90 minutes after [18F]flutemetamol administration with approximately 185 MBq injected. PET images were acquired for 30 minutes.

Results:

Amyloid PET imaging led to change in diagnosis in 15/44 clinical subjects (34%). Mean diagnostic confidence increased by approximately 20%, from 73% pre-scan to 93% post-scan, and this rise was fairly consistent across the main patient subgroups (mild cognitive impairment, AD, and non-AD) irrespective of the pre-scan diagnosis and scan result.

Conclusion:

The study examined the utility of amyloid PET imaging in a Japanese clinical cohort and highlighted the use of an etiological diagnosis in the presence of the amyloid scan. [18F]Flutemetamol PET led to a change in diagnosis in over 30% of cases and to an increase in diagnostic confidence by approximately 20% consistent with other reports.
Safety and Short-Term Oncological Outcomes of Thulium Fiber Laser En Bloc Resection of Non-Muscle-Invasive Bladder Cancer: A Prospective Non-Randomized Phase II Trial
Authors: Enikeev Dmitry , Taratkin Mark , Margulis Vitaly , Sorokin Nikolay , Severgina Lubov , Paramonova Nina , Kislyakov Dmitry , Kozlov Vasiliy , Rapoport Leonid , Shariat Shahrokh F. , Glybochko Petr
Published: June 2020

BACKGROUND:

Ongoing efforts aim at overcoming the challenges of conventional transurethral resection of bladder tumor (TURBT) such as the high recurrence rate, difficulty of pathologic interpretation and complications including wall injury.

OBJECTIVE:

To prospectively assess the safety and efficacy of Thulium fiber en bloc resection of bladder tumor (Tm-fiber ERBT) compared to TURBT.

MATERIALS AND METHODS:

The prospective non-randomized study included 129 patients with non-muscle-invasive bladder cancer (NMIBC) divided into two groups: 58 patients underwent conventional TURBT and 71 –Tm-fiber ERBT with FiberLase U1 (NTO IRE-Polus, Russia). Relapse-free survival (RFS), detrusor presence and complication rates were assessed. For multivariable analysis we used the Pearson chi-squared Hosmer-Lemeshow goodness of fit test; to compare survival –Cox regression analysis; for operative data comparison –chi-square test with Fisher’s correction; for survival analysis –the Kaplan–Meier method and logrank test.

RESULTS:

RFS rates at 3 and 6 months were 84.5% and 67.2% for conventional TURBT versus 97.2% and 91.5% for Tm-fiber ERBT ( p = 0.011 and p < 0.001, respectively). Detrusor muscle was present in 58.6% of cases treated with conventional TURBT vs 91.6% for the Tm-fiber ERBT group ( p < 0.001). The obturator nerve reflex and bleeding were noted in 17.2% and 10.3% of TURBT cases, respectively; and in none of cases treated with Tm-fiber ERBT. Limitations included the non–randomized nature and the small sample size.

CONCLUSIONS:

Tm-fiber ERBT seems to be a safe and efficacious treatment option for NMIBC. Tm-fiber ERBT had fewer adverse events, was more likely to secure detrusor muscle in the specimen and resulted in better RFS rates than conventional TURBT. Based on these promising data, we have started a prospective randomized clinical trial comparing en bloc TURBT with conventional TURBT (ClinicalTrials.gov NCT03718754).
Acute Ethanol Exposure Enhances Synaptic Plasticity in the Dorsal Striatum in Adult Male and Female Rats
Authors: Avchalumov Yosef , Piña-Crespo Juan C. , Woodward John J. , Mandyam Chitra D.
Published: June 2020

Background: Acute (ex vivo) and chronic (in vivo) alcohol exposure induces neuroplastic changes in the dorsal striatum, a critical region implicated in instrumental learning. Objective: Sex differences are evident in alcohol reward and reinforcement, with female rats consuming higher amount of alcohol in operant paradigms compared to male rats. However, sex differences in the neuroplastic changes produced by acute alcohol in the dorsal striatum have been unexplored. Methods: Using electrophysiological recordings from dorsal striatal slices obtained from adult male and female rats, we investigated the effects of ex vivo ethanol exposure on synaptic transmission and synaptic plasticity. Ethanol (44 mM) enhanced basal synaptic transmission in both sexes. Ethanol also enhanced long-term potentiation in both sexes. Other measures of synaptic plasticity including paired-pulse ratio were unaltered by ethanol in both sexes. Results: The results suggest that alterations in synaptic plasticity induced by acute ethanol, at a concentration associated with intoxication, could play an important role in alcohol-induced experience-dependent modification of corticostriatal circuits underlying the learning of goal-directed instrumental actions and formation of habits mediating alcohol seeking and taking. Conclusions: Taken together, understanding the mechanism(s) underlying alcohol induced changes in corticostriatal function may lead to the development of more effective therapeutic agents to reduce habitual drinking and seeking associated with alcohol use disorders.
Lack of early platelet and leukocyte activation can indicate complications after major burn injury
Authors: Loibl Csaba , Rozanovic Martin , Bogár Lajos , Pankaczi Andrea , Kovács Patrícia , Miseta Attila , Molnár Tihamér , Csontos Csaba
Published: June 2020

BACKGROUND: Major burn injury causes massive tissue destruction consequently enhanced platelet function and leukocyte-mediated inflammatory response. METHODS: In a prospective, observational study 23 consecutive patients with more than 20% body surface burn injury were followed for five days (T1–T5) after admission to a university intensive care (ICU). Platelet and leukocyte antisedimentation rate (PAR and LAR) was measured by one-hour gravity sedimentation. It detects the percentage of total platelet and leukocyte number crossed the half line of blood sample column, therefore, they can be regarded as cells of decreased specific gravity. We aimed to investigate the time course of PAR and LAR after burn injury, as the trend of platelet and the leukocyte activation in the early post-burn period. RESULTS: Daily mean PAR and LAR values continuously increased in the observation period (T1 to T5). Daily mean PAR and LAR were lower in ICU non-survivors (n = 7) compared to survivors (n = 16) between T2 and T4 (p < 0.05 and p < 0.01). PAR values of septic patients (n = 10) were lower than that of non-septic ones (n = 13, p < 0.01 at T5). CONCLUSIONS: Both PAR and LAR, as novel bedside test can predict septic complications and unfavorable outcome after major burn injury. Further studies with higher sample size are warranted.
Effects of ankle pump exercise frequency on venous hemodynamics of the lower limb
Authors: Li Tianhua , Yang Shuhong , Hu Fang , Geng Qian , Lu Qing , Ding Junqin
Published: June 2020

PURPOSE: The purpose of this study was (1) to compare the effects of ankle pump exercise(APE) frequency on hemodynamics of the common femoral vein(CFV) and (2) to analyse the relationship between APE duration and lower limb fatigue. METHODS: Twenty-seven males and thirty-three females performed APE. Among them, there were thirty participants with non-lower limb fracture (N-LLF) and thirty participants with lower limb fracture (LLF).The colour doppler ultrasound was used to record the time-averaged mean velocity (TAMV) of common femoral venous flow when the participants at rest and move at different frequencies of 6 times/min, 10 times/min, 30 times/min, 60 times/min. The ratings of perceived exertion (RPE) was used to assess the lower limb fatigue of the participants when performing APE at the frequency of 60 times/min after 1 min, 2 mins, 3 mins, 4 mins and 5 mins. RESULTS: With the increase of frequency, TAMV increased significantly in both the participants with N-LLF and LLF (p < 0.01). The TAMV were 19.82±3.86, 33.78±8.76, 37.06±8.67, 43.82±10.40, 52.18±10.53, respectively in the participants with N-LLF and 16.98±3.01, 22.20±4.96, 24.01±5.78, 29.20±7.05, 35.75±9.28, respectively in the injured limb of patients with LLF when at rest and moving at the frequency of 6 times/min, 10 times/min, 30 times/min, 60 times/min. There was a positive correlation (p < 0.01) between lower limb fatigue and exercise duration.When the RPE was 16 points (the corresponding fatigue degree is “tired”), the exercise duration of the participants with N-LLF was 3 mins and that of the injured limb of patients with LLF was 2 mins. CONCLUSIONS: Both fast and slow-frequency APE can promote venous blood return in the lower limb. Despite of the equivalent APE duration, fast-frequency APE can promote venous blood return more effectively. When the frequency of APE was 60 times/min, participants with N-LLF can exercise for 3 mins, and the injured limb of patients with LLF can exercise for 2 mins.
Implementing FAIR data for people and machines: Impacts and implications - results of a research data community workshop
Authors: Borycz Joshua , Carroll Bonnie
Published: June 2020

The Implementing FAIR Data for People and Machines: Impacts and Implications workshop was organized by the Board on Research Data and Information of the National Academies of Sciences, Engineering, and Medicine (NASEM), the CENDI Federal Information Managers Group, the Research Data Alliance (RDA), and the National Federation of Advanced Information Services (NFAIS), and held at NASEM’s Keck Center in Washington, DC on September 11, 2019. The goals of the Implementing FAIR Data workshop were to discuss the current status of FAIR data implementation, share what is being done to encourage scientists to share data in machine-readable formats, and examine the implications of FAIR data implementation for people and machines. FAIR data policies, tools, and measures of FAIR data compliance were considered from multiple perspectives. Marcia McNutt, President of the National Academy of Sciences (NAS), offered opening remarks, and the keynote address was presented by Barend Mons, Professor of Bioinformatics at Leiden University Medical Center and President of the International Science Council’s Committee on Data (CODATA). Three panel discussions addressed (1) the perspectives of scientists and administrators from U.S. federal agencies, (2) case studies on the implementation of FAIR data practices, and (3) principles and methods of measuring FAIR data compliance. The automation of scientific workflows was discussed by Stuart Feldman, Chief Scientist of Schmidt Futures, a philanthropic organization devoted to investing in research, technology, and science. The workshop closed with highlights and takeaways from each session as summarized by the moderators, followed by general questions.
A study of lexical function detection with word2vec and supervised machine learning
Authors: Kolesnikova Olga , Gelbukh Alexander
Published: June 2020

In this work, we report the results of our experiments on the task of distinguishing the semantics of verb-noun collocations in a Spanish corpus. This semantics was represented by four lexical functions of the Meaning-Text Theory. Each lexical function specifies a certain universal semantic concept found in any natural language. Knowledge of collocation and its semantic content is important for natural language processing, as collocation comprises the restrictions on how words can be used together. We experimented with word2vec embeddings and six supervised machine learning methods most commonly used in a wide range of natural language processing tasks. Our objective was to study the ability of word2vec embeddings to represent the context of collocations in a way that could discriminate among lexical functions. A difference from previous work with word embeddings is that we trained word2vec on a lemmatized corpus after stopwords elimination, supposing that such vectors would capture a more accurate semantic characterization. The experiments were performed on a collection of 1,131 Excelsior newspaper issues. As the experimental results showed, word2vec representation of collocations outperformed the classical bag-of-words context representation implemented in a vector space model and fed into the same supervised learning methods.
Self-attention for Twitter sentiment analysis in Spanish
Authors: González José Ángel , Hurtado Lluís-F. , Pla Ferran
Published: June 2020

This paper describes our proposal for Sentiment Analysis in Twitter for the Spanish language. The main characteristics of the system are the use of word embedding specifically trained from tweets in Spanish and the use of self-attention mechanisms that allow to consider sequences without using convolutional nor recurrent layers. These self-attention mechanisms are based on the encoders of the Transformer model. The results obtained on the Task 1 of the TASS 2019 workshop, for all the Spanish variants proposed, support the correctness and adequacy of our proposal.
Authorship attribution of Spanish poems using n-grams and the web as corpus
Authors: Guzmán-Cabrera Rafael
Published: June 2020

In many areas of professional development, the categorization of textual objects is of critical importance. A prominent example is the attribution of authorship, where symbolic information is manipulated using natural language processing techniques. In this context, one of the main limitations is the necessity of a large number of pre-labeled instances for each author that is to be identified. This paper proposes a method based on the use of n-grams of characters and the use of the web to enrich the training sets. The proposed method considers the automatic extraction of the unlabeled examples from the Web and its iterative integration into the training data set. The evaluation of the proposed approach was done by using a corpus formed by poems corresponding to 5 contemporary Mexican poets. The results presented allow evaluating the impact of the incorporation of new information into the training set, as well as the role played by the selection of classification attributes using information gain.
Extractive summarization using siamese hierarchical transformer encoders
Authors: González José Ángel , Segarra Encarna , García-Granada Fernando , Sanchis Emilio , Hurtado Lluís-F.
Published: June 2020

In this paper, we present an extractive approach to document summarization, the Siamese Hierarchical Transformer Encoders system, that is based on the use of siamese neural networks and the transformer encoders which are extended in a hierarchical way. The system, trained for binary classification, is able to assign attention scores to each sentence in the document. These scores are used to select the most relevant sentences to build the summary. The main novelty of our proposal is the use of self-attention mechanisms at sentence level for document summarization, instead of using only attentions at word level. The experimentation carried out using the CNN/DailyMail summarization corpus shows promising results in-line with the state-of-the-art.
Revisiting subject classification in academic databases: A comparison of the classification accuracy of Web of Science, Scopus & Dimensions
Authors: Singh Prashasti , Piryani Rajesh , Singh Vivek Kumar , Pinto David
Published: June 2020

Classification of research articles into different subject areas is an extremely important task in bibliometric analysis and information retrieval. There are primarily two kinds of subject classification approaches used in different academic databases: journal-based (aka source-level) and article-based (aka publication-level). The two popular academic databases- Web of Science and Scopus- use journal-based subject classification scheme for articles, which assigns articles into a subject based on the subject category assigned to the journal in which they are published. On the other hand, the recently introduced Dimensions database is the first large academic database that uses article-based subject classification scheme that assigns the article to a subject category based on its contents. Though the subject classification schemes of Web of Science have been compared in several studies, no research studies have been done on comparison of the article-based and journal-based subject classification systems in different academic databases. This paper aims to compare the accuracy of subject classification system of the three popular academic databases: Web of Science, Scopus and Dimensions through a large-scale user-based study. Results show that the commonly held belief of superiority of article-based subject classification over the journal-based subject classification scheme does not hold at least at the moment, as Web of Science appears to have the most accurate subject classification.
Brain signal classification for creative tasks
Authors: Mukhopadhyay TirthaPrasad , Cabrera Rafael Guzmán , Pinales José Ruiz , Pérez-Careta Eduardo , Thompson Reynaldo , Pérez-Crespo Armando
Published: June 2020

We tried to determine if emotive self-feedback from conscious assessment of artists’ own works generates sufficient impetus for accomplishment of goals. Self-reports from participants of an ‘experimental’ group working independently and without external feedback on their work are examined. The performance of this group is compared to ‘control’ performers in tutored sessions (with external feedback). On the whole a two-fold analysis was carried out. First, verbal reports of the participants’ feelings about their work in both experimental and control settings were analyzed. Second, a brainwave analysis of each participant was conducted while they were engaged in the same tasks so as to examine effects of concentration and energy output. The Hilbert-Huang transform was used to filter data frequency for brainwaves emitted at channels AF4, AF3, F6 and F7, all positioned along the pre-frontal cortex. Results of participants’ brainwave behavior within frequency ranges of 14–16 Hz, as well as for higher ranges (above 60 Hz), do not show significant difference in the two groups. This indicates that brainwave activity is sustained in individuals who depend on self-feedback appraisals, at least within the domain of creativity investigated in this paper.
Digital processing of ultrasound images on dilated blood vessels from diabetic patients
Authors: Cordova-Fraga Teodoro , García Daniel , Murillo-Ortiz Blanca , García Marysol , Gomez Christian , Amador-Medina Fabian , Guzman-Cabrera Rafael
Published: June 2020

Introduction Peripheral arterial disease (PAD) is a fairly common degenerative vascular condition in diabetic patients that leads to inadequate blood flow (BF), this disease is mainly due to atherosclerosis that causes chronic narrowing of arteries, which can precipitate acute thrombotic events. In patients with diabetes, atherosclerosis is the main reason for reducing life expectancy, as long as diabetic nephropathy and retinopathy are the largest contributors to end-stage renal disease and blindness, respectively. Objective This was an assessment of dilatation of the blood vessels on diabetic patients vs. healthy volunteers by using digital processing of imaging’s. Materials and Methods The study subject was ultrasound imaging processing of blood vessels dilation on low extremities of diabetic patients, the results were compared with ultrasound images of healthy subjects. Results The digital images processing suggests that there is a significant difference among images experimental of the diabetic group and healthy volunteers’ images, the control group. Discussion The digital imaging processing performed in the Matlab platform is an adequate procedure for blood vessels dilation analysis of the ultrasound images taken from the lower extremities in diabetic patients.
L-interval spaces and some of their properties
Authors: Wu Xiu-Yun
Published: June 2020

In this paper, notions of L-interval spaces and L-2-arity convex spaces are introduced. It is showed that there is a Galois’s connection between the category of L-convex spaces and the category of L-interval spaces. In particular, the category of L-2-arity convex spaces can be embedded in the category of L-interval spaces as a coreflective subcategory. Further, some properties of L-interval spaces are introduced including L-geometric (resp. L-Peano, L-Pasch and L-sand-glass) property. It is proved that an L-2-arity convex space is an L-JHC convex space iff its segment operator has L-Peano property. It is also proved that an L-JHC convex space with an L-idempotent segment operator has L-sand-glass property. Further, it is also proved that an L-idempotent interval space having L-Peano+L-Pasch property has L-geometric property and L-sand-glass property.
Lower Extremity Muscle Involvement in the Intermediate and Bethlem Myopathy Forms of COL6-Related Dystrophy and Duchenne Muscular Dystrophy: A Cross-Sectional Study
Authors: Batra Abhinandan , Lott Donovan J. , Willcocks Rebecca , Forbes Sean C. , Triplett William , Dastgir Jahannaz , Yun Pomi , Reghan Foley A. , Bönnemann Carsten G. , Vandenborne Krista , Walter Glenn A.
Published: June 2020

Collagen VI-related dystrophies (COL6-RDs) and Duchenne muscular dystrophy (DMD) cause progressive muscle weakness and disability. COL6-RDs are caused by mutations in the COL6 genes (COL6A1, COL6A2 and COL6A3) encoding the extracellular matrix protein collagen VI, and DMD is caused by mutations in the DMD gene encoding the cytoplasmic protein dystrophin. Both COL6-RDs and DMD are characterized by infiltration of the muscles by fatty and fibrotic tissue. This study examined the effect of disease pathology on skeletal muscles in lower extremity muscles of COL6-RDs using timed functional tests, strength measures and qualitative/ quantitative magnetic resonance imaging/spectroscopy measures (MRI/MRS) in comparison to unaffected (control) individuals. Patients with COL6-RD were also compared to age and gender matched patients with DMD. Patients with COL6-RD presented with a typical pattern of fatty infiltration of the muscle giving rise to an apparent halo effect around the muscle, while patients with DMD had evidence of fatty infiltration throughout the muscle areas imaged. Quantitatively, fat fraction, and transverse relaxation time (T2) were elevated in both COL6-RD and DMD patients compared to unaffected (control) individuals. Patients with COL6-RD had widespread muscle atrophy, likely contributing to weakness. In contrast, patients with DMD revealed force deficits even in muscle groups with increased contractile areas.
Ganglionopathies Associated with MERRF Syndrome: An Original Report
Authors: Michaud Maud , Stojkovic Tanya , Maisonobe Thierry , Behin Anthony , Rucheton Benoit , Léonard-Louis Sarah , Eymard Bruno , Laforêt Pascal
Published: June 2020

Neuropathies in Myoclonic Epilepsy with Ragged Red Fibers (MERRF) syndrome are frequent but ganglionopathies have never been reported. We retrospectively identified 24 patients with MERRF mutations in the neuromuscular center Nord/Est/Ile de France (Pitié-Salpêtrière, Paris, France). Seventeen nerve conduction studies (NCS) were available. Five patients had MERRF syndrome and ganglionopathy, a pure sensory neuropathy. All of them displayed ataxia and mild clinical sensory abnormalities. Ganglionopathies have been reported in mitochondrial diseases but never in MERRF syndrome. We suggest that patients presenting with ganglionopathy, especially if associated with myopathy, lipomatosis or epilepsy, should be screened for MERRF mutations.
Exploring the wall in marathon running
Authors: Berndsen Jakim , Lawlor Aonghus , Smyth Barry
Published: June 2020

The wall is an iconic feature of the marathon. If runners hit the wall, usually around the 30km (20mi) mark, their pace slows dramatically, leaving them to struggle to the finish-line. While the physiology of the wall is reasonably well understood – a critical combination of fatigue and a lack of available fuel as the body’s glycogen stores become depleted – its actual impact is less well studied. In this paper we present a large-scale data-driven study of how and when recreational marathon runners hit the wall. We do this by analysing the pacing patterns of almost 60,000 runners across more than 250 races. The main contributions are: (1) an operational definition of the wall by identifying its key pacing features; and (2) and analysis of hitting the wall for runners, based on their age, gender and ability, using this definition.
Tailored interventions to assist smokers to stop smoking using e-cigarettes (TASSE): Study protocol
Authors: Kimber Catherine , Frings Daniel , Cox Sharon , Sideropoulos Vassilis , Naughton Felix , Brown Jamie , McRobbie Hayden , Dawkins Lynne
Published: June 2020

BACKGROUND: There is increasing evidence that e-cigarettes (EC) are an effective smoking cessation aid when combined with behavioural support. There is further evidence for digital tailored interventions as cost effective approaches that can increase smoking cessation rates. Experimental work also suggests the addition of a ‘nicotine fact sheet’ can improve smokers’ risk perceptions related to EC. However, multifaceted approaches to deliver ‘tailored advice’ for smoking cessation combining various key evidenced based components are lacking. The aim of this study is to use a Multiphase Optimisation Strategy (MOST) to determine which of five, or a combination thereof, EC-orientated intervention components is associated with self-reported cessation over the previous 4-weeks at 12-week follow-up.

METHODS/DESIGN: This online study will utilise a 2x2x2x2x2 factorial design resulting in 32 experimental conditions. The five intervention components will be: 1: tailored advice on EC device; 2: tailored advice on e-liquid nicotine strength; 3: tailored advice on e-liquid flavour; 4: e-cigarette written information; 5: text message support. A sample of N=1184 adult, UK resident smokers will be randomly allocated to one of the 32 conditions, which will be permutations of the 5 components (counter-balanced). The primary outcome is 4 weeks of self-reported complete abstinence at 12 weeks post randomisation. Secondary outcomes are 7-day point prevalence, 50% reduction in baseline cigarettes smoked per day, time to switch and adherence to recommendation. The primary analysis will be by intent-to-treat with the assumption that missing equals smoking. Logistic regression will be used to model the five main effects and the ten 2x2 interactions. A number of secondary analyses will also be conducted including models adjusting for demographic and smoking indices and including only those who received the intervention. 

DISCUSSION: To date, components that assist quitting by use of EC or other aids have largely been studied in isolation. This study presents the first attempt to combine evidenced based interventions, using the MOST method, to test which components are associated with quitting. The findings will be used to inform which components to include and their estimated effect sizes for a definitive randomised controlled trial (RCT) to examine the efficacy of the intervention compared with usual care (own choice and no support).
A Cost Analysis of Overdose Management at a Supervised Consumption Site in Calgary, Canada
Authors: Jackson Jennifer
Published: June 2020

Background and Aims: We report on a cost study, using population level data to determine the impact of emergency overdose management at supervised consumption services (SCS) versus conventional services.
Design: We completed a cost analysis from a payer’s perspective. In this setting, there is a single-payer model of service delivery.
Setting: In Calgary, ‘Safeworks Harm Reduction Program,’ was established in late 2017 and offers 24/7 access to SCS. The facility is a nurse-led service, available for client drop-in. We conducted a cost analysis for the entire duration of the program. This covers two years and three months.
Measurements: We assessed costs using the following factors, using government health databases: monthly operational costs of providing services for drug consumption, cost of providing EMS for clients with overdoses who could not be revived at the facility, and benefit of EMS costs averted from overdoses that were successfully managed at the SCS.
Findings: The proportion of clients who have overdosed at the SCS has decreased steadily for the duration of the program. The number of overdoses that can be managed on site at the SCS has trended upward, currently 98%. Each overdose that is managed at the SCS produces approximately $1,600 CAD in cost savings, with a savings of over $2.3 million for the lifetime of the program.
Conclusions: Overdose management at an SCS creates cost savings by offsetting costs required for managing overdoses using emergency services.
Demografía, inmigración y futuro de la seguridad social en la CEE
Authors: Gommers Peter
Published: June 2020

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Capacidad directiva como respuesta empresarial al proceso de integración en la comunidad europea
Authors: García Echevarría Santiago
Published: June 2020

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La ciudad como escenario de la postmodernidad
Authors: Lozano Josep M.
Published: June 2020

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Tipologías de animación sociocultural
Authors: López Ceballos Paloma
Published: June 2020

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El lenguaje, la elaboración y la recepción del discurso social de la iglesia.
Authors: Sanz De Diego Rafael
Published: June 2020

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Algunos problemas de la propiedad en Juan Pablo II.
Authors: Rodríguez Federico
Published: June 2020

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Збагачення фортепіанного репертуару майбутніх військових диригентів як удосконалення їхньої професійної майстерності
Authors: Ваврик Руслана
Published: June 2020

У контексті вдосконалення професійної майстерності майбутніх військових диригентів перед викладачами загальних і спеціалізованих музичних дисциплін кафедри музичного мистецтва Національної академії сухопутних військ постає завдання пошуку різних шляхів реалізації цієї мети. Один із них – збагачення навчально-педагогічного репертуару з навчальної дисципліни «Фортепіано» музичними творами сучасних авторів. Головною метою при викладанні дисципліни є досягнення здатності курсантом самостійно виконувати музичний твір на високохудожньому професійному рівні та майстерно донести до слухача його образно-емоційний зміст. Підвищення музично-виконавських вимог до майбутніх військових диригентів, стислі часові обмеження при повному обсязі практичного вивчення музичних творів згідно робочого навчального плану з навчальної дисципліни «Фортепіано» вимагає від викладача створення відповідних умов на уроці для засвоєння навчального матеріалу, впровадження інновацій, застосування методики викладання предмета з урахуванням музичних здібностей кожного учня задля подальшого зростання його професійного рівня. У процесі викладання дисципліни специфіка навчально-педагогічного репертуару з фортепіано охоплює такі твори, як етюди, поліфонічні твори, п’єси малих форм, твори великої форми, ансамблеві твори, акомпанемент та ін. Фортепіанний репертуар має охоплювати найрізноманітніші музичні твори українських і зарубіжних композиторів, йому повинна бути властива висока художня змістовність, відповідна педагогічна доцільність з урахуванням загального музичного розвитку й індивідуальних особливостей кожного курсанта. У даній публікації вперше представлено результати творчого пошуку щодо збагачення навчально-педагогічного фортепіанного репертуару майбутніх військових диригентів із навчальної дисципліни «Фортепіано» викладача з багаторічним практичним досвідом у напрямі викладання гри на фортепіано, композитора Руслани Ваврик. Докладно проаналізовано чотири твори для фортепіано: п’єси «Радість» і «Забавка», етюди для розвитку піаністичної техніки № 1 (a-moll) і № 2 (a-moll), а також твір, написаний у жанрі романсу для голосу з фортепіано «Квітка і душа» на вірші поетеси й композитора Мар’яни Лиховид. Дані твори також можуть стати основою для подальшого вивчення та апробації студентами й учнями мистецьких закладів музичного спрямування.
Особливості стресостійкості й адаптивних здібностей до стресу майбутніх військовослужбовців
Authors: Бурбан Наталія , Бурбан Наталія , Гузенко Ірина
Published: June 2020

У статті з’ясовано розуміння стресостійкості й адаптивності в наукових джерелах та емпірично досліджено статистично значущі відмінності стресостійкості й адаптивних здібностей у майбутніх військовослужбовців і представників студентської молоді, з’ясовано психологічний зміст цих відмінностей. Стресостійкість переважно розуміється як психофізичний стан людини, який забезпечує оптимальну адаптацію до екстремальних умов, що дозволяє вирішувати покладені на неї службові та побутові завдання, перебуваючи в стані психофізичної рівноваги, а адаптивність розглядається як здібності, які включають у себе підсистеми індивідних, особистісних і суб’єктних властивостей, які забезпечують ефективне соціальне та професійне функціонування в умовах сильного стресу з мінімальними затратами індивідуальних психофізіологічних ресурсів і збереження психічного та соматичного здоров’я. Особливості стресостійкості майбутніх військовослужбовців виявляються у більшій задоволеності життям, у вищому, ніж у студентів, рівні стресостійкості. Крім того, у них більше розвинуті такі адаптивні здібності до подолання стресу, як оптимізм, адаптивне мислення, адаптивний сон і сновидіння. Курсанти впевненіші в собі, краще вміють управляти своїм психофізіологічним станом і здійснювати соматичну регуляцію, організовувати свій час, в цілому в них високий рівень адаптивності до стресу, на відміну від студентів цивільних вишів. Майбутні військовослужбовці більш схильні до активної життєвої позиції, життєлюбності, почуття гумору, високої мотивації, у них вищі самоконтроль і гнучкість мислення, а також здатність дистанціюватися від травматичних подій. У майбутніх військовослужбовців більше розвинуті пунктуальність, вміння раціонально розпоряджатися часом, планувати і визначати пріоритети у своїх справах.
Математична підготовка фахівців служби цивільного захисту як невід’ємна складова професійної підготовки
Authors: Кусій Мирослава , Карабин Оксана
Published: June 2020

Визначено основні процеси, які необхідно реалізувати на заняттях із вищої математики для майбутніх фахівців цивільного захисту (усвідомлення, осмислення, засвоєння). Зазначено, що для процесу осмислення необхідно навчити курсантів і студентів створювати математичні моделі. Наведено приклади таких задач. Визначено фактори (мети і завдань, повноти і якості викладання, складності, місця і значення окремої теми в подальшому вивченні предмета, місця і значення дисципліни у професійному застосуванні, можливостей і вміння викладача переконати студентів і курсантів у важливості навчального предмета, вибору викладачем раціональних методів, прийомів, засобів і способів викладання) та педагогічні технології (особистісно орієнтована, модульна, ситуаційного навчання, повного засвоєння, імітаційні, ігрові, дискусії), які впливають на процес засвоєння знань. Виокремлено особливості (операційна, аналітична, когнітивна, евристична), які впливають на розвиток професійних якостей майбутніх фахівців цивільного захисту в контексті математичної підготовки.
Психотерапія як елемент профілактики соціальної інтеграції
Authors: Бартошевський Якуб , Сікорська Леся
Published: June 2020

У статті показано, що люди, які знаходяться у важкій ситуації, мають вищі очікування від психотерапевтів щодо підтримки, ніж від духівників, оскільки сподіваються, що психотерапевти зможуть перешкодити їх соціальній ізоляції. Вони очікують від психотерапевтів: високої кваліфікації, знань, компетентності, навичок спілкування, наполегливості, працьовитості, навичок планування й організаційних навичок. Проте у сфері розуміння потреб інших людей респонденти вказують, що психотерапевти повинні характеризуватися високою емпатією. Вони очікують від них дружніх і приятельських відносин, що, на жаль, суперечить професійній етиці даного фахівця. Існує реальна різниця між очікуваннями осіб, які потребують соціальної підтримки, щодо професійних особливостей реального й ідеального фахівця-психотерапевта, щодо його самоконтролю, впевненості в собі, особистісної адаптації, ідеального образу себе, почуття мужності та жіночності. Психотерапевти значною мірою не володіють високою оригінальністю, вони використовують так звану театральність у поведінці, мають проблеми з логічним мисленням. Вони, в основному, не прагматики, вони виявляють ригідне мислення. Люди, які потребують соціальної підтримки, очікують від фахівця психолога чи психотерапевта високого інтелекту та здатності вирішувати проблеми. Незначні відмінності між реальним та ідеальним фахівцем виявлено у таких властивостях, як заангажованість у працю, пошук нового досвіду і переживань, прагнення схвалення, творче ставлення до дійсності. Розкриті особливості психотерапевтів, які виконують превентивні завдання в інклюзії, відрізняються від тих, які постулюються і в той же час очікуються тими, хто отримує підтримку. Фахівець, який у своїй діяльності опирається на знання, навички та компетентності, спроможний зібрати інформацію про потреби пацієнта, включаючи і духовні елементи. Він може використовувати ці духовні елементи як психотерапевтичні методи й інструменти. Такий фахівець здатний торкатися теми духовності як елементу психотерапії для запобігання соціальній ізоляції.
Формування іншомовної компетентності майбутніх економістів: зарубіжний досвід
Authors: Чернявський Богдан
Published: June 2020

У статті розглядається зарубіжний досвід формування іноземної мови для майбутніх економістів. Такі європейські країни, як Великобританія, Німеччина, Фінляндія, Естонія, Італія, були взяті для розгляду зарубіжного досвіду формування іноземної мови для майбутніх економістів. Проте кожна національна система освіти має свої акценти та особливості. Таким чином, в різних країнах метою навчання є: професійне формування іноземної мови майбутнього економіста, який реалізує принцип вивчення іноземної мови для професійної орієнтації (Великобританія, Німеччина, Фінляндія, Естонія), виховання майбутнього фахівця, для якого іноземна мова є засобом спілкування в інтегрованому освітньому середовищі (Фінляндія), орієнтація на практичну діяльність і постійне поліпшення своїх професійних якостей (Італія). Проведені дослідження свідчать про широку мінливість системи формування іноземної мови для майбутніх економістів у сучасному світі відповідно до динамічності її розвитку. Безумовно, такий міжнародний досвід є цінним ресурсом для розвитку та насичення нових ідей для вітчизняної практики формування іноземної мови для майбутніх економістів.