bluuebunny/crossref_metadata_2025 huggingface dataset:
The Remote Control of the Artillery Rocket Set as a Strongly Nonlinear System Subject to Random Loads
Authors: Koruba Zbigniew , Szmidt Piotr
Published: June 2021

On the modern battlefield, fighting capabilities, such as speed, target detection range, target identification capabilities, and shooting effectiveness, of short-range artillery rocket sets (ARSs) are constantly being improved. Problems arise when attempting to successfully fire such kits in the face of disruption from both the cannon and the moving platform on which the cannon is mounted. Furthermore, the set is a variable mass system since it can fire anywhere from a few to dozens or even hundreds of missiles in a brief period of time, implying that the ARS is a highly nonlinear system of variable parameters (non-stationary). This work shows how to control such a system. If the ARS is placed on a moving basis where there is both a system and measurement noise, the state variables must be restored, and the ARS data must be filtered. Therefore, in addition to the LQR regulator, an extended Kalman filter was used. As a consequence of this synthesis, an LQG (linear quadratic Gaussian) regulator of ARS was obtained, which was used to follow the target along the line of sight. The key goal of this paper is to develop control algorithms that will increase the performance of ARS control in elevation and azimuth, as well as the accuracy of achieving and eliminating maneuverable air targets. Moreover, through the quality criterion adopted, we hope to affect control energy costs while maintaining control precision. Graphical representations of certain computational simulation results are provided.
Presence of Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) in Food Contact Materials (FCM) and Its Migration to Food
Authors: Ramírez Carnero Arabela , Lestido-Cardama Antía , Vazquez Loureiro Patricia , Barbosa-Pereira Letricia , Rodríguez Bernaldo de Quirós Ana , Sendón Raquel
Published: June 2021

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are synthetic chemical compounds widely used in different industry fields including food contact materials (FCM), providing resistance to fat and humidity, and non-stick properties. PFAS enter into the food chain directly from the intake of contaminated food or indirectly from the migration of the FCM into the food. This exposure published in different research highlights a public health concern. Therefore, it is necessary to perform analysis of the content of different FCM and evaluate the migration from the FCM under normal conditions of use and storage. This bibliographical review proves that different perfluoroalkyl and polyfluoroalkyl compounds are detected in fast food packaging, microwave popcorn bags, and frying pans, among others. Furthermore, it shows the conditions or factors that favor the migration of the PFAS from the FCM into the food.
Application of Absorption and Scattering Properties Obtained through Image Pre-Classification Method Using a Laser Backscattering Imaging System to Detect Kiwifruit Chilling Injury
Authors: Yang Zhuo , Li Mo , East Andrew R. , Zude-Sasse Manuela
Published: June 2021

Kiwifruit chilling injury (CI) damage occurs after long-term exposure to low temperature. A non-destructive approach to detect CI injury was tested in the present study, using a laser backscattering image (LBI) technique calibrated with 56 liquid phantoms for providing absorption coefficient (µa) and reduced scattering coefficient (µs’). Calibration of LBI resulted in a true-positive (TP) classification of 91.5% and 65.6% of predicted µs’ and µa, respectively. The optical properties of ‘SunGold™’and ‘Hayward’ kiwifruit were analysed at 520 nm with a two-step protocol capturing pre-classification according to the LBI parameters used in the calibration and estimation with the Farrell equation. Severely injured kiwifruit showed white corky tissue and water soaking, reduced soluble solids content and firmness measured destructively. Non-destructive classification results for ‘SunGold™’ showed a high percentage of TP for severe CI of 92% and 75% using LBI parameters directly and predicted µa and µs’ after pre-classification, respectively. The classification accuracy for severe CI ‘Hayward’ kiwifruit with LBI parameter was low (58%) and with µa and µs’ decreased further (35%), which was assumed to be due to interference caused by the long trichomes on the fruit surface.
Non-Alcoholic Pearl Millet Beverage Innovation with Own Bioburden: Leuconostoc mesenteroides, Pediococcus pentosaceus and Enterococcus gallinarum
Authors: Jideani Victoria A. , Ratau Mmaphuti A. , Okudoh Vincent I.
Published: June 2021

The appropriate solution to the problem of quality variability and microbial stability of traditional non-alcoholic pearl millet fermented beverages (NAPMFB) is the use of starter cultures. However, potential starter cultures need to be tested in the production process. We aimed to identify and purify bioburden lactic acid bacteria from naturally fermented pearl millet slurry (PMS) and assess their effectiveness as cultures for the production of NAPMFB. Following the traditional Kunun-zaki process, the PMS was naturally fermented at 37 °C for 36 h. The pH, total titratable acidity (TTA), lactic acid bacteria (LAB), total viable count (TVC) and the soluble sugar were determined at 3 h interval. The presumptive LAB bacteria were characterized using a scanning electron microscope, biochemical tests and identified using the VITEK 2 Advanced Expert System for microbial identification. The changes in pH and TTA followed a non-linear exponential model with the rate of significant pH decrease of 0.071 h−1, and TTA was inversely proportional to the pH at the rate of 0.042 h−1. The Gompertz model with the mean relative deviation modulus, 0.7% for LAB and 2.01% for TVC explained the variability in microbial growth during fermentation. The LAB increased significantly from 6.97 to 7.68 log cfu/mL being dominated by Leuconostoc, Pediococcus, Streptococcus and Enterococcus with an optimum fermentation time of 18 h at 37 °C and 4.06 pH. L. mesenteroides and P. pentosaceus created an acidic environment while E. gallinarum increased the pH of the pearl millet extract (PME). Innovative NAPMFB was produced through assessment of LAB from PMS to PME fermented with L. mesentoroides (0.05%) and P. pentosaceus (0.025%) for 18 h, thereby reducing the production time from the traditional 24 h.
Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry
Authors: Marrale Maurizio , d’Errico Francesco
Published: June 2021

Radiation-sensitive gels are among the most recent and promising developments for radiation therapy (RT) dosimetry. RT dosimetry has the twofold goal of ensuring the quality of the treatment and the radiation protection of the patient. Benchmark dosimetry for acceptance testing and commissioning of RT systems is still based on ionization chambers. However, even the smallest chambers cannot resolve the steep dose gradients of up to 30–50% per mm generated with the most advanced techniques. While a multitude of systems based, e.g., on luminescence, silicon diodes and radiochromic materials have been developed, they do not allow the truly continuous 3D dose measurements offered by radiation-sensitive gels. The gels are tissue equivalent, so they also serve as phantoms, and their response is largely independent of radiation quality and dose rate. Some of them are infused with ferrous sulfate and rely on the radiation-induced oxidation of ferrous ions to ferric ions (Fricke-gels). Other formulations consist of monomers dispersed in a gelatinous medium (Polyacrylamide gels) and rely on radiation-induced polymerization, which creates a stable polymer structure. In both gel types, irradiation causes changes in proton relaxation rates that are proportional to locally absorbed dose and can be imaged using magnetic resonance imaging (MRI). Changes in color and/or opacification of the gels also occur upon irradiation, allowing the use of optical tomography techniques. In this work, we review both Fricke and polyacrylamide gels with emphasis on their chemical and physical properties and on their applications for radiation dosimetry.
Pincho: A Modular Approach to High Quality De Novo Transcriptomics
Authors: Ortiz Randy , Gera Priyanka , Rivera Christopher , Santos Juan C.
Published: June 2021

Transcriptomic reconstructions without reference (i.e., de novo) are common for data samples derived from non-model biological systems. These assemblies involve massive parallel short read sequence reconstructions from experiments, but they usually employ ad-hoc bioinformatic workflows that exhibit limited standardization and customization. The increasing number of transcriptome assembly software continues to provide little room for standardization which is exacerbated by the lack of studies on modularity that compare the effects of assembler synergy. We developed a customizable management workflow for de novo transcriptomics that includes modular units for short read cleaning, assembly, validation, annotation, and expression analysis by connecting twenty-five individual bioinformatic tools. With our software tool, we were able to compare the assessment scores based on 129 distinct single-, bi- and tri-assembler combinations with diverse k-mer size selections. Our results demonstrate a drastic increase in the quality of transcriptome assemblies with bi- and tri- assembler combinations. We aim for our software to improve de novo transcriptome reconstructions for the ever-growing landscape of RNA-seq data derived from non-model systems. We offer guidance to ensure the most complete transcriptomic reconstructions via the inclusion of modular multi-assembly software controlled from a single master console.
Ocular Involvement in Hereditary Amyloidosis
Authors: Minnella Angelo Maria , Rissotto Roberta , Antoniazzi Elena , Di Girolamo Marco , Luigetti Marco , Maceroni Martina , Bacherini Daniela , Falsini Benedetto , Rizzo Stanislao , Obici Laura
Published: June 2021

The term amyloidosis describes a group of rare diseases caused by protein conformation abnormalities resulting in extracellular deposition and accumulation of insoluble fibrillar aggregates. So far, 36 amyloid precursor proteins have been identified, and each one is responsible for a specific disease entity. Transthyretin amyloidosis (ATTRv) is one of the most common forms of systemic and ocular amyloidosis, due to the deposition of transthyretin (TTR), which is a transport protein mainly synthesized in the liver but also in the retinal pigment epithelial cells. ATTRv amyloidosis may be misdiagnosed with several other conditions, resulting in a significant diagnostic delay. Gelsolin and keratoepithelin are other proteins that, when mutated, are responsible for a systemic amyloid disease with significant ocular manifestations that not infrequently appear before systemic involvement. The main signs of ocular amyloid deposition are in the cornea, irido-corneal angle and vitreous, causing complications related to vasculopathy and neuropathy at the local level. This review aims at describing the main biochemical, histopathological and clinical features of systemic amyloidosis associated with eye involvement, with particular emphasis on the inherited forms. We discuss currently available treatments, focusing on ocular involvement and specific ophthalmologic management and highlighting the importance of a prompt treatment for the potential sight-threatening complications derived from amyloid deposition in ocular tissues.
Effects of Water Stress on the Phenolic Compounds of ‘Merlot’ Grapes in a Semi-Arid Mediterranean Climate
Authors: Chacón-Vozmediano Juan L. , Martínez-Gascueña Jesús , García-Romero Esteban , Gómez-Alonso Sergio , García-Navarro Francisco J. , Jiménez-Ballesta Raimundo
Published: June 2021

Of all the abiotic stress types to which plants grown in fields are exposed, the most influential is water stress. It is well accepted that adopting controlled deficit irrigation strategies during the growing season has beneficial effects on the chemical compositions of grapes and red wines. However, there is a discrepancy in the timing, intensity and duration of deficit. This study aimed to evaluate the changes in phenolic composition of ‘merlot’ cultivar grapes when subjected to different levels of water stress in a semi-arid Mediterranean climate. Four treatments with different water stress levels were applied within two phenological intervals (flowering-veraison, veraison-maturity) to 128 grapevines for two consecutive years. The water stress levels for Treatments 1, 2, 3 and 4 were: no-light, light-moderate, moderate-intense and intense for the flowering-veraison and veraison-maturity intervals, respectively. Water stress distinctly affected the phenolic compounds in skin and seeds. The concentrations of flavan-3-ols and total polyphenols were much higher in seeds than in skin, and in both fractions, tannins are the major compounds.
The Effects of Residential Built Environment on Supporting Physical Activity Diversity in High-Density Cities: A Case Study in Shenzhen, China
Authors: Gao Yuan , Liu Kun , Zhou Peiling , Xie Hongkun
Published: June 2021

In high-density cities, physical activity (PA) diversity is an essential indicator of public health and urban vitality, and how to meet the demands of diverse PA in a limited residential built environment is critical for promoting public health. This study selected Shenzhen, China, as a representative case; combined the diversity of PA participants, types, and occurrence times to generate a comprehensive understanding of PA diversity; fully used data from multiple sources to measure and analyze PA diversity and residential built environment; analyzed the relationships between the built environment and PA diversity; and explored the different effects in clustered and sprawled high-density urban forms. PAs in clustered areas were two times more diverse than those in sprawled areas. Accessibility, inclusiveness, and landscape attractiveness of residential built environment jointly improved PA diversity. Clustered areas had significant advantages in supporting PA diversity since they could keep the balance between dense residence and landscape reservation with an accessible and inclusive public space system. The residential built environment with dense street networks, public traffic and service, multi-functional public space system, and attractive landscapes is crucial to improve the diverse PA to achieve more public health outputs in high-density cities. To promote health-oriented urban development, clustered urban form is advocated, and step-forward strategies should be carried out.
Physical Activity Level Following Resistance Training in Community-Dwelling Older Adults Receiving Home Care: Results from a Cluster-Randomized Controlled Trial
Authors: Bårdstu Hilde Bremseth , Andersen Vidar , Fimland Marius Steiro , Aasdahl Lene , Lohne-Seiler Hilde , Saeterbakken Atle Hole
Published: June 2021

Older adults’ physical activity (PA) is low. We examined whether eight months of resistance training increased PA level in community-dwelling older adults receiving home care. A two-armed cluster-randomized trial using parallel groups was conducted. The included participants were >70 years and received home care. The resistance training group performed resistance training using body weight, elastic bands, and water canes twice per week for eight months. The control group was informed about the national PA guidelines and received motivational talks. The ActiGraph GT3X+ accelerometer was used to estimate PA. Outcomes included total PA (counts per minute), sedentary behavior (min/day), light PA (min/day), moderate-to-vigorous PA (min/day), and steps (mean/day). Between-group differences were analyzed using multilevel linear mixed models. Twelve clusters were randomized to either resistance training (7 clusters, 60 participants) or the control group (5 clusters, 44 participants). A total of 101 participants (median age 86.0 (interquartile range 80–90) years) had valid accelerometer data and were included in the analysis. There were no statistically significant between-group differences for any of the PA outcomes after four or eight months. This study offers no evidence of increased PA level following resistance training in older adults with home care.
The Effects of Korean Parents’ Smartphone Addiction on Korean Children’s Smartphone Addiction: Moderating Effects of Children’s Gender and Age
Authors: Son Hye-Gyeong , Cho Heeran J. , Jeong Kyu-Hyoung
Published: June 2021

Background: Smartphone addiction among children and adolescents has a negative effect, as excessive use of smartphones can cause physical symptoms, such as fatigue, indigestion, and sleep problems, as well as psychopathological problems, such as depression, anxiety, and impulsiveness. Materials and Methods: This study was carried out using the Korean Children and Youth Panel Survey 2019 conducted by the National Youth Policy Institute. The total number of participants was 4656 youths (2290 in grade 5 and 2366 in grade 8), and the dependent and independent variables were smartphone addiction in children and parents, respectively. Multiple regression analysis was conducted by Stata 15.0 SE. Results: First, the level of parents’ smartphone addiction affected that of children and adolescents. Second, the children’s and adolescents’ age affected the level of smartphone addiction, while their gender did not affect it. Third, the relationship between the levels of parents’ and children’s smartphone addiction was not moderated by the genders and ages of the children and adolescents. Conclusions: It was confirmed that as parents’ smartphone addiction increased, that of children increased, and smartphone addiction was found to increase in the second grade of middle school (12 years old) rather than grade 5 of elementary school (10 years old). Parents’ and children’s smartphone addiction was not moderated by children’s and adolescents’ gender and age.
Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders
Authors: Calderón-Garcidueñas Lilian , Rajkumar Ravi Philip , Stommel Elijah W. , Kulesza Randy , Mansour Yusra , Rico-Villanueva Adriana , Flores-Vázquez Jorge Orlando , Brito-Aguilar Rafael , Ramírez-Sánchez Silvia , García-Alonso Griselda , Chávez-Franco Diana A. , Luévano-Castro Samuel C. , García-Rojas Edgar , Revueltas-Ficachi Paula , Villarreal-Ríos Rodolfo , Mukherjee Partha S.
Published: June 2021

Quadruple aberrant hyperphosphorylated tau (p-τ), amyloid-β peptide, alpha-synuclein and TDP-43 brainstem and supratentorial pathology are documented in forensic ≤40y autopsies in Metropolitan Mexico City (MMC), and p-τ is the major aberrant protein. Post-traumatic stress disorder (PTSD) is associated with an elevated risk of subsequent dementia, and rapid eye movement sleep behavior disorder (RBD) is documented in PD, AD, Lewy body dementia and ALS. This study aimed to identify an association between PTSD and potential pRBD in Mexico. An anonymous online survey of 4502 urban college-educated adults, 29.3 ± 10.3 years; MMC, n = 1865; non-MMC, n = 2637, measured PTSD symptoms using the Impact of Event Scale–Revised (IES-R) and pRBD symptoms using the RBD Single-Question. Over 50% of the participants had IES-R scores ≥33 indicating probable PTSD. pRBD was identified in 22.6% of the participants across Mexico and 32.7% in MMC residents with PTSD. MMC subjects with PTSD had an OR 2.6218 [2.5348, 2.7117] of answering yes to the pRBD. PTSD and pRBD were more common in women. This study showed an association between PTSD and pRBD, strengthening the possibility of a connection with misfolded proteinopathies in young urbanites. We need to confirm the RBD diagnosis using an overnight polysomnogram. Mexican women are at high risk for stress and sleep disorders.
Relationship Between Air Pollution and the Concentration of Nitric Oxide in the Exhaled Air (FeNO) in 8–9-Year-Old School Children in Krakow
Authors: Czubaj-Kowal Marta , Kurzawa Ryszard , Mazurek Henryk , Sokołowski Michał , Friediger Teresa , Polak Maciej , Nowicki Grzegorz Józef
Published: June 2021

The consequences of air pollution pose one of the most serious threats to human health, and especially impact children from large agglomerations. The measurement of nitric oxide concentration in exhaled air (FeNO) is a valuable biomarker in detecting and monitoring airway inflammation. However, only a few studies have assessed the relationship between FeNO and the level of air pollution. The study aims to estimate the concentration of FeNO in the population of children aged 8–9 attending the third grade of public primary schools in Krakow, as well as to determine the relationship between FeNO concentration and dust and gaseous air pollutants. The research included 4580 children aged 8–9 years who had two FeNO measurements in the winter–autumn and spring–summer periods. The degree of air pollution was obtained from the Regional Inspectorate of Environmental Protection in Krakow. The concentration of pollutants was obtained from three measurement stations located in different parts of the city. The FeNO results were related to air pollution parameters. The study showed weak but significant relationships between FeNO and air pollution parameters. The most significant positive correlations were found for CO8h (r = 0.1491, p < 0.001), C6H6 (r = 0.1420, p < 0.001), PM10 (r = 0.1054, p < 0.001) and PM2.5 (r = 0.1112, p < 0.001). We suggest that particulate and gaseous air pollutants impact FeNO concentration in children aged 8–9 years. More research is needed to assess the impact of air pollution on FeNO concentration in children. The results of such studies could help to explain the increase in the number of allergic and respiratory diseases seen in children in recent decades.
Funeral and Mortuary Operators: The Role of Stigma, Incivility, Work Meaningfulness and Work–Family Relation to Explain Occupational Burnout
Authors: Guidetti Gloria , Grandi Annalisa , Converso Daniela , Bosco Nicoletta , Fantinelli Stefania , Zito Margherita , Colombo Lara
Published: June 2021

The funeral and mortuary sector, including funeral homes, cemeteries and crematoria, is a largely neglected sector in regard to the study of occupational factors that can affect the quality of working life. The present study aimed at overcoming this gap by investigating job demands and resources that may affect burnout levels. Data were collected through a self-report questionnaire involving funeral industry employees (N = 229) from cemetery, morgues, crematoria and funeral agencies in a Northern Italian region. The survey was cross-sectional and non-randomized. Results reveal that among job demands, stigma consciousness, supervisor incivility and work-to-family negative spillover significantly affect levels of burnout, whereas meaningfulness of work and family-to-work positive spillover may represent relevant resources to counter the onset of burnout. The results of this study contribute to new insights into the psychosocial working conditions that affect occupational wellbeing among the funeral industry sector by also giving insight into how to promote resources to prevent burnout.
Propensity Score Analysis with Partially Observed Baseline Covariates: A Practical Comparison of Methods for Handling Missing Data
Authors: Bottigliengo Daniele , Lorenzoni Giulia , Ocagli Honoria , Martinato Matteo , Berchialla Paola , Gregori Dario
Published: June 2021

(1) Background: Propensity score methods gained popularity in non-interventional clinical studies. As it may often occur in observational datasets, some values in baseline covariates are missing for some patients. The present study aims to compare the performances of popular statistical methods to deal with missing data in propensity score analysis. (2) Methods: Methods that account for missing data during the estimation process and methods based on the imputation of missing values, such as multiple imputations, were considered. The methods were applied on the dataset of an ongoing prospective registry for the treatment of unprotected left main coronary artery disease. The performances were assessed in terms of the overall balance of baseline covariates. (3) Results: Methods that explicitly deal with missing data were superior to classical complete case analysis. The best balance was observed when propensity scores were estimated with a method that accounts for missing data using a stochastic approximation of the expectation-maximization algorithm. (4) Conclusions: If missing at random mechanism is plausible, methods that use missing data to estimate propensity score or impute them should be preferred. Sensitivity analyses are encouraged to evaluate the implications methods used to handle missing data and estimate propensity score.
Alexithymia Is Linked with a Negative Bias for Past and Current Events in Healthy Humans
Authors: Barchetta Silvia , Martino Gabriella , Craparo Giuseppe , Salehinejad Mohammad A. , Nitsche Michael A. , Vicario Carmelo M.
Published: June 2021

Although research provides a rich literature about the influence of emotional states on temporal cognition, evidence about the influence of the style of emotion processing, as a personality trait, on temporal cognition is extremely limited. We provide a novel contribution to the field by exploring the relationship between difficulties of identifying and describing feelings and emotions (alexithymia) and time perspective. One hundred and forty-two healthy participants completed an online version of the TAS-20 scale, which measures alexithymia, and the Zimbardo Time Perspective Inventory, which monitors individual differences in time-orientation regarding the past, present, and future. The results show greater attention to past negative aspects in participants whose TAS-20 score was indicating borderline or manifest alexithymia, as compared to non-alexithymic individuals. Moreover, the higher the TAS-20 score, the higher the tendency was to focus on negative aspects of the past and interpret the present fatalistically. These results suggest that difficulties in identifying and describing feelings and emotions are associated with a negative bias for past and present events. Theoretical and clinical implications of this finding are discussed.
Exploring the Engaged Worker over Time—A Week-Level Study of How Positive and Negative Work Events Affect Work Engagement
Authors: Weigelt Oliver , Schmitt Antje , Syrek Christine J. , Ohly Sandra
Published: June 2021

Although work events can be regarded as pivotal elements of organizational life, only a few studies have examined how positive and negative events relate to and combine to affect work engagement over time. Theory suggests that, to better understand how current events affect work engagement (WE), we have to account for recent events that have preceded these current events. We present competing theoretical views on how recent and current work events may affect employees (e.g., getting used to a high frequency of negative events or becoming more sensitive to negative events). Although the occurrence of events implies discrete changes in the experience of work, prior research has not considered whether work events actually accumulate to sustained mid-term changes in WE. To address these gaps in the literature, we conducted a week-level longitudinal study across a period of 15 consecutive weeks among 135 employees, which yielded 849 weekly observations. While positive events were associated with higher levels of WE within the same week, negative events were not. Our results support neither satiation nor sensitization processes. However, a high frequency of negative events in the preceding week amplified the beneficial effects of positive events on WE in the current week. Growth curve analyses show that the benefits of positive events accumulate to sustain high levels of WE. WE dissipates in the absence of a continuous experience of positive events. Our study adds a temporal component by highlighting that positive events affect work engagement, particularly in light of recent negative events. Our study informs research that has taken a feature-oriented perspective on the dynamic interplay of job demands and resources.
Factors Favoring and Hindering Volunteering by Older Adults and Their Relationship with Subjective Well-Being: A Mixed-Method Approach
Authors: Serrat-Graboleda Eva , González-Carrasco Mònica , Casas Aznar Ferran , Malo Cerrato Sara , Cámara Liebana David , Roqueta-Vall-Llosera Marta
Published: June 2021

A mixed methodology was used through the triangulation of quantitative and qualitative data to determine older adults’ perspectives regarding volunteering and identify what factors can contribute to promoting it, with special emphasis on the role that their own well-being plays in this behavior. The results reveal that satisfaction with life as a whole contributes positively to volunteer behavior and satisfaction with the groups one belongs to contributes negatively. The volunteers were less satisfied than non-volunteers with interpersonal relationships and with the groups they belong to. Knowing the opinion of the older adults with regard to volunteering and understanding how this prosocial behavior relates to their own well-being is very useful for developing strategic plans that allow future volunteers to be captured.
REDECA: A Novel Framework to Review Artificial Intelligence and Its Applications in Occupational Safety and Health
Authors: Pishgar Maryam , Issa Salah Fuad , Sietsema Margaret , Pratap Preethi , Darabi Houshang
Published: June 2021

Introduction: The field of artificial intelligence (AI) is rapidly expanding, with many applications seen routinely in health care, industry, and education, and increasingly in workplaces. Although there is growing evidence of applications of AI in workplaces across all industries to simplify and/or automate tasks there is a limited understanding of the role that AI contributes in addressing occupational safety and health (OSH) concerns. Methods: This paper introduces a new framework called Risk Evolution, Detection, Evaluation, and Control of Accidents (REDECA) that highlights the role that AI plays in the anticipation and control of exposure risks in a worker’s immediate environment. Two hundred and sixty AI papers across five sectors (oil and gas, mining, transportation, construction, and agriculture) were reviewed using the REDECA framework to highlight current applications and gaps in OSH and AI fields. Results: The REDECA framework highlighted the unique attributes and research focus of each of the five industrial sectors. The majority of evidence of AI in OSH research within the oil/gas and transportation sectors focused on the development of sensors to detect hazardous situations. In construction the focus was on the use of sensors to detect incidents. The research in the agriculture sector focused on sensors and actuators that removed workers from hazardous conditions. Application of the REDECA framework highlighted AI/OSH strengths and opportunities in various industries and potential areas for collaboration. Conclusions: As AI applications across industries continue to increase, further exploration of the benefits and challenges of AI applications in OSH is needed to optimally protect worker health, safety and well-being.
Performance of the Cognitive Performance Scale of the Resident Assessment Instrument (interRAI) for Detecting Dementia amongst Older Adults in the Community
Authors: Gee Susan , Croucher Matthew , Cheung Gary
Published: June 2021

The Cognitive Performance Scale (CPS) in the widely used interRAI suite of instruments is of interest to clinicians and policy makers as a potential screening mechanism for detecting dementia. However, there has been little evaluation of the CPS in home care settings. This retrospective diagnostic study included 134 older adults (age ≥ 65) who were discharged from two acute psychogeriatric inpatient units or assessed in two memory clinics. The reference test was a diagnosis of clinical dementia, and the index test was interRAI CPS measured within 90 days of discharge. The overall accuracy of the CPS was good, with an area under the Receiver Operating Characteristic curve of 0.82 (95% CI = 0.75–0.89). The optimal cut point was 1/2, coinciding with the recommended cut point, with good sensitivity (0.90, 95% CI = 0.81–0.96) but poor specificity (0.60, 95% CI = 0.46–0.72). Positive predictive value improved from 0.72 (95% CI = 0.66–0.78) to 0.89 (95% CI = 0.75–0.96) when using a cut point of 2/3 instead of 1/2. If the results of the present study are replicated with more generalisable interRAI samples, older adults with a CPS of 3 or above, but without a formal diagnosis of dementia, should be referred for further cognitive assessment.
The Importance of an Emotional Expression Guide to Prevent Work-Related Health Problems in Emotional Laborers
Authors: Ha Ji Sun , Kim Jin Ah
Published: June 2021

Background: As the service industry develops, the proportion of emotional laborers is gradually increasing, and their occupational health problems are gradually becoming serious social problems. Researchers must consider various factors, from the personal to the organizational levels, to prevent health problems from arising in the workplace. Many intervention studies have investigated the health and wellbeing of workers, but mainly at the individual level, even though an organization’s interest and efforts are essential for addressing work-related health problems. Therefore, the purpose of this study was to verify the importance of organizations’ interests to protect emotional laborers from work-related health problems. Methods: We used data obtained through the 4th Korean Working Condition Survey of 2014. The study cohort comprised 5857 survey participants over the age of 18 years. Employers, self-employed persons and professional soldiers were excluded. Logistic regression was employed to identify associations between an emotional expression guide and work-related health problems using SPSS 22.0 statistical software. Results: In the absence of an emotional expression guide, the risk of work-related physical and psychological health problems was increased. Even after adjusting for confounding variables, the risks were statistically maintained, particularly headache (odds ratio (OR) 1.798; 95% confidence interval 95% CI: 1.288–2.508), lower limb muscular pain (OR: 1.627; 95% CI: 1.130–2.342), general fatigue (OR: 1.582; 95% CI: 1.077–2.326) and depressive symptom (OR: 6.149; 95% CI: 1.198–31.563). Conclusion: This study showed that organizations’ interests and efforts to prevent workers from being harmed by the effects of emotional labor are important in the prevention of psychosocial and physical health problems; therefore, a national interest in supporting emotional laborers and in introducing policies to support these workers should be established.
Community-Based Monitoring in the New Normal: A Strategy for Tackling the COVID-19 Pandemic in Malaysia
Authors: Muhamad Khair Nur Khairlida , Lee Khai Ern , Mokhtar Mazlin
Published: June 2021

In 2020, the COVID-19 pandemic severely impacted the global public health system and led to many deaths worldwide. COVID-19 is highly contagious and can be spread by symptomatic or asymptomatic individuals. As such, determining the risk of infection within a community is difficult. To mitigate the risk of the spread of COVID-19, the government of Malaysia implemented seven phases of the movement control order (MCO) from 18 March to 31 December 2020. However, the socioeconomic cost was substantial despite the effectiveness of the MCO in bringing down cases of infection. As noted by the Prime Minister of Malaysia, the final criterion that should be met is community empowerment. In other words, community-based mitigation measures through which communities unite to contain the pandemic are essential before the completion of the vaccination program. As a measure for controlling the pandemic, mitigation strategies in the new normal should be feasible, practical, and acceptable to communities. In this paper, we present a deliberation of a set of community-based monitoring criteria to ensure health and well-being in communities, such as efficacy, technicality, feedback, and sustainability. The proposed criteria will be instrumental in developing community-based monitoring initiatives to achieve the desired goals in coping with the pandemic as well as in empowering communities to be part of the governance process.
The Educational Community in the Face of COVID-19. Discursive Analysis on Vulnerability and Education
Authors: López-Noguero Fernando , Gallardo-López José Alberto , García-Lázaro Irene
Published: June 2021

This article presents the results of research the objective of which was to know the opinion of directors of different educational centers about the management carried out in their centers and the possible difficulties encountered during the suspension of face-to-face classes caused by the first wave of the COVID-19 pandemic. The research method is qualitative, exploratory, descriptive, and inductive. The study sample is made up of 43 managers of educational centers, who were selected by applying an intentional sampling based on criteria of age, experience, ownership of the center, teachings that are taught, and the socioeconomic context where it is located. A questionnaire was used to collect the information, previously designed and validated through the judgment of experts, to inquire about the organization and management from the management team, the development of the academic task with the students, and the relationship with the families during the course period of cessation of classroom activities. To make an adequate approximation to the reality studied, an exhaustive content analysis of the speeches issued by the participants was carried out. Among the main conclusions of the research are the difficulties they have experienced during the closure of schools in relation to the lack of strategic planning to reconvert face-to-face education to the online format, scarcity of technological resources in centers and homes, training deficit in digital skills, increasing the digital divide, attention to students with special educational needs or communication problems with students and their families.
Chronic Back Condition and the Level of Physical Activity as Well as Internet Addiction among Physiotherapy Students during the COVID-19 Pandemic in Poland
Authors: Gałczyk Monika , Zalewska Anna , Białokoz-Kalinowska Irena , Sobolewski Marek
Published: June 2021

Objectives: The aim of this study was to assess back pain and its relation to physical activity as well as Internet addiction among Polish university students during the COVID-19 pandemic. Methods: The research was conducted via the Internet in student groups of three universities in Poland (141 people). Back pain was examined by ODI—The Oswestry Disability Index and NDI—Neck Disability Index. The Polish-language International Physical Activity Questionnaire (IPAQ) was used to assess physical activity and the level of Internet addiction was tested using the Kimberly Young Questionnaire. Results: The respondents mostly suffered from pain originating in the cervical spine. In the study group, only every fifth person had a high level of physical activity. Sex differentiates the level of the measures considered. Sitting in front of the computer affects the pain in the spine. Conclusions: Research results suggest that the pandemic is negatively affecting students. Frequent occurrence of back pain is observed with a simultaneous low level of physical activity. Maintaining regular activity during a pandemic, at least at home, is an indispensable preventive measure for physical health.
A Novel Image Processing Approach to Enhancement and Compression of X-ray Images
Authors: Pourasad Yaghoub , Cavallaro Fausto
Published: June 2021

At present, there is an increase in the capacity of data generated and stored in the medical area. Thus, for the efficient handling of these extensive data, the compression methods need to be re-explored by considering the algorithm’s complexity. To reduce the redundancy of the contents of the image, thus increasing the ability to store or transfer information in optimal form, an image processing approach needs to be considered. So, in this study, two compression techniques, namely lossless compression and lossy compression, were applied for image compression, which preserves the image quality. Moreover, some enhancing techniques to increase the quality of a compressed image were employed. These methods were investigated, and several comparison results are demonstrated. Finally, the performance metrics were extracted and analyzed based on state-of-the-art methods. PSNR, MSE, and SSIM are three performance metrics that were used for the sample medical images. Detailed analysis of the measurement metrics demonstrates better efficiency than the other image processing techniques. This study helps to better understand these strategies and assists researchers in selecting a more appropriate technique for a given use case.
Survey of Smart Contract Framework and Its Application
Authors: Negara Edi , Hidayanto Achmad , Andryani Ria , Syaputra Rezki
Published: June 2021

This article is a literature review on smart contract applications in various domains. The aim is to investigate technological developments and implementation of smart contracts in various domains. For this purpose, the theoretical basis of various papers that have been published in recent years is used as a source of theoretical and implementation studies. Smart contracts are the latest technology that is developing in line with the development of blockchain technology. The literature review that we have carried out explains that smart contracts work automatically, control, or document legally relevant events and actions in accordance with the agreements set forth in the contract agreement. This technology is one of the newest technologies that is expected to provide solutions for trust, security, and transparency in various domains. This literature review was conducted using an exploratory approach. This literature review focuses on reviewing frameworks, methods, and simulations of smart contract implementations in various domains.
Towards Flexible Retrieval, Integration and Analysis of JSON Data Sets through Fuzzy Sets: A Case Study
Authors: Fosci Paolo , Psaila Giuseppe
Published: June 2021

How to exploit the incredible variety of JSON data sets currently available on the Internet, for example, on Open Data portals? The traditional approach would require getting them from the portals, then storing them into some JSON document store and integrating them within the document store. However, once data are integrated, the lack of a query language that provides flexible querying capabilities could prevent analysts from successfully completing their analysis. In this paper, we show how the J-CO Framework, a novel framework that we developed at the University of Bergamo (Italy) to manage large collections of JSON documents, is a unique and innovative tool that provides analysts with querying capabilities based on fuzzy sets over JSON data sets. Its query language, called J-CO-QL, is continuously evolving to increase potential applications; the most recent extensions give analysts the capability to retrieve data sets directly from web portals as well as constructs to apply fuzzy set theory to JSON documents and to provide analysts with the capability to perform imprecise queries on documents by means of flexible soft conditions. This paper presents a practical case study in which real data sets are retrieved, integrated and analyzed to effectively show the unique and innovative capabilities of the J-CO Framework.
Clinicopathological Significance of Syndecan-1 in Cholangiocarcinoma: A Study Based on Immunohistochemistry and Public Sequencing Data
Authors: Gerber Tiemo S. , Bartsch Fabian , Wagner Daniel C. , Schindeldecker Mario , Heuft Lisa-Katharina , Roth Wilfried , Lang Hauke , Straub Beate K.
Published: June 2021

Background: Syndecan-1 (CD138; SDC1) is a heparan sulfate proteoglycan that has been attributed a key role in cancer progression in ductal adenocarcinoma of the pancreas. We therefore aimed to investigate the role of syndecan-1 in cholangiocarcinoma. Methods: We analyzed syndecan-1 expression in a large, clinicopathologically well-characterized collective of 154 intrahepatic cholangiocarcinoma, 221 extrahepatic cholangiocarcinomas, and 95 gallbladder carcinomas as well as respective normal tissues and precursor lesions by immunohistochemistry with digital image analysis and correlated with recurrence-free survival and prognostic markers. Furthermore, we conducted an analysis of cancer genes in the cholangiocarcinoma cohort of The Cancer Genome Atlas (TCGA). Results: During cholangiocarcinogenesis, syndecan-1-expression decreased when compared to normal bile ducts and biliary intraepithelial neoplasia; however, syndecan-1 levels were found to be elevated in lymph node metastases. In the TCGA cohort, high mRNA SDC1 levels were associated with poor prognosis in intrahepatic cholangiocarcinoma. However, in our large cohort, the immunohistochemical syndecan-1 expression did not significantly correlate with recurrence-free survival. Conclusions: Syndecan-1 was found to be downregulated during cholangiocarcinogenesis, yet we could not show significant effects on prognosis on protein level. Further analyses are needed to further depict its specific role.
Cognitive Tic-Like Phenomena in Gilles de la Tourette Syndrome
Authors: Janik Piotr , Dunalska Anna , Szejko Natalia , Jakubczyk Andrzej
Published: June 2021

Coprolalia and echophenomena repeated in the patients’ mind (CTPh—cognitive tic-like phenomena) have been rarely recognized as part of Gilles de la Tourette syndrome (GTS) symptomatology and their assignment to tics, OCD or other psychopathologies has not been settled. The aim of the paper was to assess the incidence and clinical associations of CTPh in GTS, and to establish if CTPh belong to the tic spectrum. We performed a prospective, one-registration study on a cohort of 227 consecutive patients with GTS. CTPh were diagnosed during the interview and defined as brief, sudden, involuntary thoughts that had corresponding complex vocal tics. CTPh occurred at some point in the lives of 34 (15.0%) patients. The median age at onset of CTPh was 14.5 years (IQR: 10.5–17.5). CTPh were found more frequently in adults, with the most frequent onset in adolescence (44.1%). Four mental phenomena resembling tics were recognized: echolalia (n = 17), coprolalia (n = 16), palilalia (n = 13) and repeating of words in the mind (n = 7). The older the age of patients, the more severe tics, and anxiety disorder significantly correlated with CTPh. CTPh may be considered as a part of tic spectrum with a substantial impact of anxiety disorder. CTPh are a late and age-related symptom of GTS.