bluuebunny/crossref_metadata_2025 huggingface dataset:
Universal or selective ultrasound screening for developmental dysplasia of the hip? A discussion of the key issues
Authors: Biedermann R. , Eastwood D. M.
Published: August 2018

Purpose

To summarize recent developments and provide recommendations as to whether universal or selective programmes are advisable.

Methods

A literature review was performed and preference given to studies with higher levels of evidence. All programmes reviewed included clinical screening.

Results

Recent studies underline the need for high quality screening programmes to promote the early detection of developmental dysplasia of the hip (DDH). A small number of cases may be missed clinically but with universal ultrasound screening programmes the late presentation rates appear to be virtually zero. Contemporary studies show treatment rates with universal screening programmes which are now lower than those with selective ultrasound. There is little agreement over the criteria used for selective programmes. Alternative outcome measures, such as the first operation rate or the percentage undergoing major (open) surgery are both lowest with universal ultrasound screening programmes. Furthermore, a significant reduction in the rate of surgery for DDH later in life was seen after the introduction of universal ultrasound screening, whereas the defined criteria for selective screening may not detect the majority of patients who require late surgery. Abduction bracing with modern orthoses is associated with a zero rate of avascular necrosis (AVN), whereas closed reduction techniques have an overall risk of 10%.

Conclusion

On clinical grounds, if future studies confirm that hip abduction in flexible orthoses is not associated with AVN, it may be time for a paradigm shift of screening for DDH towards a universal ultrasound protocol. The costs associated both with each type of screening programme and with the management of late presenting cases are also important but may be secondary to clinical benefit.
Long-term outcome after anterolateral open reduction and Salter osteotomy for late presenting developmental dysplasia of the hip
Authors: Thomas S. R. Y. W.
Published: August 2018

Introduction

Only a handful of studies report outcomes after open reduction for developmental hip dislocation beyond skeletal maturity. For successfully reduced hips it is the outcome into late adulthood on which the results of this intervention should be judged. These studies indicate clearly the importance of preservation of the acetabular growth centres during surgery. The acetabulum must also be addressed when insufficient growth remains reliably to remodel residual dysplasia even after stable, concentric reduction.

Comparing the longest-term outcome studies for open reduction to less invasive, but mainly historical, techniques of gradual traction reduction it is unsettling to note that the latter protocols are associated with the best results. Whereas open reduction and innominate osteotomy are practised as originally described by Salter, gradual traction reduction has largely been abandoned.

Conclusions

There are probably aspects of the more time-consuming methods of gradual reduction that do not violate the hip joint capsule that expose the femoral head to a lower risk of femoral head osteonecrosis leading to better long-term outcomes.
Outcomes following open reduction for late-presenting developmental dysplasia of the hip
Authors: Castañeda P. , Masrouha K. Z. , Ruiz C. Vidal , Moscona-Mishy L.
Published: August 2018

Purpose

Patients with late-presenting developmental dysplasia of the hip (DDH) are more likely to require an open reduction. Since many developing countries do not have mandated screening, there continues to be a relatively high incidence of late-presenting DDH. We report the clinical and radiographic outcomes of open reduction in a series of patients who presented late.

Patients and methods

This was a retrospective review of 712 hips in 645 patients that underwent open reduction, alone or in combination with a pelvic osteotomy. In all, 91 hips had open reduction alone and 621 had open reduction and pelvic osteotomy. Femoral shortening was performed in 221 hips. The mean age at the time of surgery was 2.1 years (1 to 6.5) and the mean follow-up time was 9.3 years (6 to 14). We used the Children's Hospital Oakland Hip Evaluation Score (CHOHES) to determine functional outcomes and the Severin classification was used to evaluate radiographic outcomes. The rate of avascular necrosis (AVN) and the need for a reoperation were also recorded and analyzed.

Results

In all 80% (570 hips) had good radiographic outcomes (Severin type I or II) and 87% had a CHOHES score of > 90 at final follow up. There was a 14% rate of AVN and only a 2% rate of redislocation. Better radiographic outcomes and lower reoperation rates were seen with patients who underwent both an open reduction and pelvic osteotomy. A trend was observed towards worse outcomes in older patients.

Conclusions

There was a high rate of good clinical and radiographic outcomes at a minimum six-year follow-up in patients with late-presenting DDH who underwent open reduction. Those who underwent open reduction in combination with a pelvic osteotomy had a higher rate of good radiographic outcomes and a lower rate of complications, particularly reoperation.
Dega pelvic osteotomy: Indications, results and complications
Authors: Czubak J. , Kowalik K. , Kawalec A. , Kwiatkowska M.
Published: August 2018

Purpose

Developmental dysplasia of the hip (DDH) after walking age is difficult to treat. Dega pelvic osteotomy is combined with open reduction and femoral osteotomy to obtain concentric stable reduction with good coverage of the femoral head. The purpose of this study is to evaluate the use of the Dega osteotomy in the treatment of DDH in two different age groups.

Methods

A total of 45 patients (52 hips) with a mean age of 3.9 years (1.2 to 12.8) were treated with open reduction, Dega osteotomy and femoral osteotomy. There were 38 dislocated and 14 subluxated hips. Bilateral DDH was observed in seven female patients. Radiographic parameters included acetabular index, centre-edge angle of Wiberg and migration percentage. The final radiographic outcome was evaluated according to the Severin classification.

Results

The mean follow-up period was four years (3 to 9). According to the Severin criteria 78.8% were types I or II whereas 21.2% showed types III or IV. There was no statistically significant difference in final outcome between children less than three years of age and older children at the time of surgery. One hip in children with unilateral involvement had developed coxa magna, that interfered with hip concentricity. Three hips (5.8%) showed avascular necrosis of the femoral head.

Conclusion

Dega osteotomy is a safe and adequate procedure for the management of developmental dysplasia of the hip in walking patients with low complication rates. Restoring the acetabulum to normal or nearly normal can result in good medium-term results.

Level of Evidence

III
O cuidado a hipertensos e diabéticos na perspectiva da Política Nacional de Humanização
Authors: Curioletti Regina Maria , Colliselli Liane , Faganello Madureira Valéria Silvana , Hermes Thomas Tombini Larissa
Published: August 2018

Objetivo: conhecer como os profissionais da equipe de saúde da família conduzem o processo de cuidar de portadores de diabetes mellitus e hipertensão arterial sistêmica. Métodos: trata-se de estudo exploratório descritivo de abordagem qualitativa desenvolvido em um Município do Norte do Estado do Rio Grande do Sul no segundo semestre de 2014, com um grupo de dez portadores de diabetes e hipertensão e três profissionais da equipe de saúde da família. A análise temática foi empregada para o tratamento dos dados e tomando a Política Nacional de Humanização como referencial teórico. Resultados: demonstram avanços em relação a implementação da Política Nacional de Humanização e desafios em relação ao projeto terapêutico singular e à clínica ampliada. Considerações finais: conclui-se que ações de educação permanente, na perspectiva da Política Nacional de Humanização são necessárias visando a qualificar o cuidado.Descritores: Atenção primária à saúde; Doença crônica; Humanização da assistência; Educação em enfermagem.
ANÁLISE E ADERÊNCIA DAS PRÁTICAS DE GESTÃO E RESPONSABILIDADE AMBIENTAL ADOTADAS PELA NATULAB LABORATÓRIOS S/A EM RELAÇÃO AS EMPRESAS DO SETOR DE MEDICAMENTOS LISTADAS NA B3/ANALYSIS AND ADHERENCE OF MANAGEMENT PRACTICES AND ENVIRONMENTAL RESPONSIBILITY ADOPTED BY NATULAB LABORATÓRIOS S/A IN RELATION AS COMPANIES OF THE SECTOR OF MEDICINES LISTED IN B3
Authors: Souza Antônio Nadson Mascarenhas , Meurer Alison Martins , Anzilago Marcielle
Published: August 2018

Este estudo tem como objetivo analisar as práticas de gestão e responsabilidade ambiental adotadas pela Natulab Laboratórios S/A bem como verificar a aderência dessas ações em relação as empresas do setor farmacêutico listadas na B3, por meio de uma pesquisa descritiva de cunho predominantemente qualitativo. Para a análise das informações divulgadas pelas organizações em seus Relatórios de Administração e/ou endereços eletrônicos, elaborou-se um índice de evidenciação das práticas ambientais, a partir de estudos anteriores. De modo adicional, realizou-se uma entrevista com o responsável pela gestão ambiental da Natulab para verificar em profundidade as ações da empresa. Os resultados revelam que a Natulab possui maior volume de evidenciação e que as ações e políticas adotadas pela organização alinham-se com os elementos tratados na literatura. Ademais, os achados apontam que as práticas ambientais além de posicionarem a empresa estrategicamente sob a legitimidade positiva perante a sociedade, podem trazer retornos financeiros. As contribuições teóricas abarcam-se nas evidências empíricas propostas pelo trabalho e fornecem introspecções para pesquisas futuras que desejam analisar as práticas de gestão e responsabilidade ambiental.
DIAGNÓSTICO DE GESTÃO AMBIENTAL NO SETOR DE CERÂMICA VERMELHA/DIAGNOSIS ENVIRONMENTAL MANAGEMENT IN THE RED CERAMICS SECTOR
Authors: Sarquis Aléssio Bessa , Sehnem Simone , Pizzinatto Nadia Kassouf , Martinazzo Júnior José Carlos
Published: August 2018

O estudo analisou a situação da gestão ambiental no setor de cerâmica vermelha na região de Rio do Sul/SC, com base nas estratégias e ações ambientais implementadas nos últimos 3 anos. Para isso, um estudo qualitativo foi realizado e envolveu a coleta de dados junto a organismos de regulação ambiental, clientes e dirigentes de uma organização do setor, por meio de entrevista em profundidade e levantamento documental. Os resultados apresentam as principais estratégias ambientais utilizadas pela organização: obtenção de certificação de conformidade, participação em programas de qualidade-produtividade, uso de biomassa no processo de queima, reutilização de parte dos produtos com não conformidades, redução do consumo de água, comercialização de resíduos e práticas de produção mais limpa. O estudo revelou também que, na região estudada, o setor de cerâmica vermelha apresenta processos produtivos semi-artesanais, elevado índice de desperdício, problemas ambientais e falta de profissionalização na estrutura produtiva e administrativa.
EDITORIAL
Authors: Silveira-Martins Elvis
Published: August 2018

Editorial
Sphingosine Kinase Regulates Neuropeptide Secretion During the Oxidative Stress-Response Through Intertissue Signaling
Authors: Kim Sungjin , Sieburth Derek
Published: August 2018

The Nrf2 antioxidant transcription factor promotes redox homeostasis in part through reciprocal signaling between neurons and neighboring cells, but the signals involved in intertissue signaling in response to Nrf2 activation are not well defined. InCaenorhabditis elegans, activation of SKN-1/Nrf2 in the intestine negatively regulates neuropeptide secretion from motor neurons. Here, we show that sphingosine kinase (SPHK-1) functions downstream of SKN-1/Nrf2 in the intestine to regulate neuropeptide secretion from motor neurons during the oxidative stress response inC. eleganshermaphrodites. SPHK-1 localizes to mitochondria in the intestine and SPHK-1 mitochondrial localization and kinase activity are essential for its function in regulating motor neuron function. SPHK-1 is recruited to mitochondria from cytosolic pools and its mitochondrial abundance is negatively regulated by acute or chronic SKN-1 activation. Finally, the regulation of motor function by SKN-1 requires the activation of the p38 MAPK cascade in the intestine and occurs through controlling the biogenesis or maturation of dense core vesicles in motor neurons. These findings show that the inhibition of SPHK-1 in the intestine by SKN-1 negatively regulates neuropeptide secretion from motor neurons, revealing a new mechanism by which SPHK-1 signaling mediates its effects on neuronal function in response to oxidative stress.

SIGNIFICANCE STATEMENTNeurons are highly susceptible to damage by oxidative stress, yet have limited capacity to activate the SKN-1/Nrf2 oxidative stress response, relying instead on astrocytes to provide redox homeostasis. InCaenorhabditis elegans, intertissue signaling from the intestine plays a key role in regulating neuronal function during the oxidative stress response. Here, through a combination of genetic, behavioral, and fluorescent imaging approaches, we found that sphingosine kinase functions in the SKN-1/Nrf2 pathway in the intestine to regulate neuropeptide biogenesis and secretion in motor neurons. These results implicate sphingolipid signaling as a new component of the oxidative stress response and suggest thatC. elegansmay be a genetically tractable model to study non-cell-autonomous oxidative stress signaling to neurons.
On Wick calculus on spaces of nonregular generalized functions of Levy white noise analysis
Authors: Kachanovsky N.A.
Published: August 2018

Development of a theory of test and generalized functions depending on infinitely many variables is an important and actual problem, which is stipulated by requirements of physics and mathematics. One of  successful approaches to building of such a theory consists in introduction of spaces of the above-mentioned functions in such a way that the dual pairing between test and generalized functions is generated by integration with respect to some probability measure. First it was the Gaussian measure, then it were realized numerous generalizations. In particular, important results can be obtained if one uses the Levy white noise measure, the corresponding theory is called the Levy white noise analysis.

In the Gaussian case one can construct spaces of test and generalized functions and introduce some important operators (e.g., stochastic integrals and derivatives) on these spaces by means of a so-called chaotic representation property (CRP): roughly speaking, any square integrable random variable can be decomposed in a series of repeated Itos stochastic integrals from nonrandom functions. In the Levy analysis there is no the CRP, but there are different generalizations of this property.

In this paper we deal with one of the most useful and challenging generalizations of the CRP in the Levy analysis, which is proposed by E.W. Lytvynov, and with corresponding spaces of nonregular generalized functions. The goal of the paper is to introduce a natural product (a Wick product) on these spaces, and to study some related topics. Main results are theorems about properties of the Wick product and of Wick versions of holomorphic functions. In particular, we prove that an operator of stochastic differentiation satisfies the Leibniz rule with respect to the Wick multiplication. In addition we show that the Wick products and the Wick versions of holomorphic functions, defined on the spaces of regular and nonregular generalized functions, constructed by means of Lytvynov's generalization of the CRP, coincide on intersections of these spaces.

Our research is a contribution in a further development of the Levy white noise analysis.
Translation, modulation and dilation systems in set-valued signal processing
Authors: Levent H. , Yilmaz Y.
Published: August 2018

In this paper, we investigate a very important function space consists of set-valued functions defined on the set of real numbers with values on the space of all compact-convex subsets of complex numbers for which the $p$th power of their norm is integrable. In general, this space is denoted by $L^{p}% (\mathbb{R},\Omega(\mathbb{C}))$ for $1\leq p<\infty$ and it has an algebraic structure named as a quasilinear space which is a generalization of a classical linear space. Further, we introduce an inner-product (set-valued inner product) on $L^{2}(\mathbb{R},\Omega(\mathbb{C}))$ and we think it is especially important to manage interval-valued data and interval-based signal processing. This also can be used in imprecise expectations. The definition of inner-product on $L^{2}(\mathbb{R},\Omega(\mathbb{C}))$ is based on Aumann integral which is ready for use integration of set-valued functions and we show that the space $L^{2}(\mathbb{R},\Omega(\mathbb{C}))$ is a Hilbert quasilinear space. Finally, we give translation, modulation and dilation operators which are three fundational set-valued operators on Hilbert quasilinear space $L^{2}(\mathbb{R},\Omega(\mathbb{C}))$.
Invariant idempotent measures
Authors: Mazurenko N. , Zarichnyi M.
Published: August 2018

The idempotent mathematics is a part of mathematics in which arithmetic operations in the reals are replaced by idempotent operations. In the idempotent mathematics, the notion of idempotent measure (Maslov measure) is a counterpart of the notion of probability measure. The idempotent measures found numerous applications in mathematics and related areas, in particular,  the optimization theory, mathematical morphology, and game theory.

In this note we introduce the notion of invariant idempotent measure for an iterated function system in a complete metric space. This is an idempotent counterpart of the notion of invariant probability measure defined by Hutchinson. Remark that the notion of invariant idempotent measure was previously considered by the authors for the class of ultrametric spaces.

One of the main results is the existence and uniqueness theorem for the invariant idempotent measures in complete metric spaces. Unlikely to the corresponding Hutchinson's result for invariant probability measures, our proof does not rely on metrization of the space of idempotent measures.

An analogous result can be also proved for the so-called in-homogeneous idempotent measures in complete metric spaces.

Also, our considerations can be extended to the case of the max-min measures in complete metric spaces.
On the structure of least common multiple matrices from some class of matrices
Authors: Romaniv A.M.
Published: August 2018

For non-singular matrices with some restrictions, we establish the relationships between Smith normal forms and transforming matrices (a invertible matrices that transform the matrix to its Smith normal form) of two matrices with corresponding matrices of their least common right multiple over a commutative principal ideal domains. Thus, for such a class of matrices, given answer to the well-known task of M. Newman. Moreover, for such matrices, received a new method for finding their least common right multiple which is based on the search for its Smith normal form and transforming matrices.
Some properties of shift operators on algebras generated by $*$-polynomials
Authors: Vasylyshyn T.V.
Published: August 2018

A $*$-polynomial is a function on a complex Banach space $X,$ which is a sum of so-called $(p,q)$-polynomials. In turn, for non-negative integers $p$ and $q,$ a $(p,q)$-polynomial is a function on $X,$ which is the restriction to the diagonal of some mapping, defined on the Cartesian power $X^{p+q},$ which is linear with respect to every of its first $p$ arguments and antilinear with respect to every of its other $q$ arguments. The set of all continuous $*$-polynomials on $X$ form an algebra, which contains the algebra of all continuous polynomials on $X$ as a proper subalgebra. So, completions of this algebra with respect to some natural norms are wider classes of functions than algebras of holomorphic functions. On the other hand, due to the similarity of structures of $*$-polynomials and polynomials, for the investigation of such completions one can use the technique, developed for the investigation of holomorphic functions on Banach spaces.

We investigate the Frechet algebra of functions on a complex Banach space, which is the completion of the algebra of all continuous $*$-polynomials with respect to the countable system of norms, equivalent to norms of the uniform convergence on closed balls of the space. We establish some properties of shift operators (which act as the addition of some fixed element of the underlying space to the argument of a function) on this algebra. In particular, we show that shift operators are well-defined continuous linear operators. Also we prove some estimates for norms of values of shift operators. Using these results, we investigate one special class of functions from the algebra, which is important in the description of the spectrum (the set of all maximal ideals) of the algebra.
On the convergence of multidimensional S-fractions with independent variables
Authors: Bodnar O.S. , Dmytryshyn R.I.
Published: August 2018

In this paper, we investigate the convergence of multidimensional S-fractions with independent variables, which are a multidimensional generalization of S-fractions. These branched continued fractions are an efficient tool for the approximation of multivariable functions, which are represented by formal multiple power series. For establishing the convergence criteria, we use the convergence continuation theorem to extend the convergence, already known for a small region, to a larger region. As a result, we have shown that the intersection of the interior of the parabola and the open disk is the domain of convergence of a multidimensional S-fraction with independent variables. And, also, we have shown that the interior of the parabola is the domain of convergence of a branched continued fraction, which is reciprocal to the multidimensional S-fraction with independent variables. In addition, we have obtained two new convergence criteria for S-fractions as a consequences from the above mentioned results.
Boundary value problem solution existence for linear integro-differential equations with many delays
Authors: Cherevko I.M. , Dorosh A.B.
Published: August 2018

For the study of boundary value problems for delay differential equations, the contraction mapping principle and topological methods are used to obtain sufficient conditions for the existence of a solution of differential equations with a constant delay. In this paper, the ideas of the contraction mapping principle are used to obtain sufficient conditions for the existence of a solution of linear boundary value problems for integro-differential equations with many variable delays.

Smoothness properties of the solutions of such equations are studied and the definition of the boundary value problem solution is proposed. Properties of the variable delays are analyzed and functional space is obtained in which the boundary value problem is equivalent to a special integral equation. Sufficient, simple for practical verification coefficient conditions for the original equation are found under which there exists a unique solution of the boundary value problem.
La inteligencia emocional en educación primaria y su relación con el rendimiento académico
Authors: Valenzuela-Santoyo Alba Del Carmen , Portillo-Peñuelas Samuel Alejandro
Published: August 2018

En el presente estudio se aborda la inteligencia emocional en educación primaria desde la perspectiva de habilidades afectivas personales y sociales que ayudan a un individuo a conocerse a sí mismo y a relacionarse mejor con las demás personas. Tiene como objetivo analizar la relación entre la inteligencia emocional y el rendimiento académico en estudiantes de nivel primaria de una institución pública. El análisis se ubica en el paradigma cuantitativo, de diseño transversal, no experimental. Se establecen el factor de inteligencia emocional desde las dimensiones de percepción, regulación y comprensión, las cuales se relacionan con el rendimiento académico. Se utilizó el instrumento TMMS-24 para la variable de inteligencia emocional y la calificación final del ciclo escolar 2013-2014 del alumnado para el rendimiento académico. Para encontrar correlaciones positivas y negativas se utilizó la r de Pearson en el análisis de resultados. Se contó con la participación de 58 participantes de quinto y sexto grado. La escuela se ubica en la zona escolar 017 de la comisaria de Pueblo Yaqui, Cajeme, Sonora. Dentro de los hallazgos se destaca la relación significativa entre la inteligencia emocional y el rendimiento académico en el alumnado de educación primaria, y se concluye que un correcto manejo de las emociones es esencial para un buen rendimiento académico estudiantil en la escuela.
Deconstruyendo la noción de inclusión: Un análisis de investigaciones, políticas y prácticas en educación
Authors: Armijo-Cabrera Muriel
Published: August 2018

Este artículo plantea que la noción de inclusión, que es usada tanto por las políticas públicas como por la investigación en educación, abarca dos conceptos distintos e incompatibles en la producción de conocimiento: la educación inclusiva y la inclusión social en la escuela. Este estudio deconstruye la noción de inclusión en educación a partir del análisis de textos teóricos y fuentes internacionales de investigación científica en educación (2000-2015). Se presentan tres hallazgos principales que diferencian los dos conceptos: (1) son procesos de naturaleza distinta, fundados en definiciones y lenguajes específicos; (2) tienen distintas concepciones de la democracia, que influencian su focalización en la escuela o en la sociedad; y (3) descansan en principios ontológicos distintos, equidad o igualdad, determinando prácticas de implementación contradictorias. En conclusión, se sugiere considerar el concepto que sustente las futuras investigaciones en educación para proponer estudios, políticas y prácticas de acuerdo con el marco ontológico adoptado.
Adolescent E-Cigarette, Hookah, and Conventional Cigarette Use and Subsequent Marijuana Use
Authors: Audrain-McGovern Janet , Stone Matthew D. , Barrington-Trimis Jessica , Unger Jennifer B. , Leventhal Adam M.
Published: August 2018

OBJECTIVES:

Noncigarette tobacco products may confer a risk of marijuana use similar to combustible cigarettes. We examined whether adolescent electronic cigarette (e-cigarette), hookah, or combustible cigarette use is associated with initiating and currently using marijuana as well as using both tobacco and marijuana concurrently.

METHODS:

Adolescents from 10 public schools in Los Angeles, California, completed in-classroom surveys at baseline (fall 2013, ninth grade) and at a 24-month follow-up (fall 2015, 11th grade). Among adolescents who never used marijuana at baseline (N = 2668), associations of baseline e-cigarette, hookah, or combustible cigarette use with ever marijuana use (initiation), current marijuana use (past 30 days), and current dual use of marijuana and these tobacco products at the 24-month follow-up were examined.

RESULTS:

Baseline ever versus never e-cigarette use was associated with initiation (odds ratio [OR] 3.63; 95% confidence interval [CI] 2.69–4.90) and current (OR 3.67; 95% CI 2.51–5.36) marijuana use 24 months later. Ever versus never hookah use was associated with initiation (OR 3.55; 95% CI 2.49–5.08) and current (OR 4.10; 95% CI 2.69–6.25) marijuana use 24 months later. Similar associations were observed for combustible cigarette smoking and initiation (OR 4.30; 95% CI 2.79–6.63) and current use of marijuana (OR 1.97; 95% CI 1.05–3.68). Current use of any of these tobacco products at baseline was associated with current use of both tobacco and marijuana (OR 2.28; 95% CI 1.47–3.55) 24 months later.

CONCLUSIONS:

The association between tobacco use and subsequent marijuana use across adolescence extends to multiple tobacco products.
La acción colectiva feminista, ¿de la lucha de clases a la lucha de géneros? Apuntes para la comprensión/práctica de los movimientos sociales, en torno al caso “Ni Una Menos”
Authors: Castro Luis Carlos
Published: August 2018

Este artículo busca explicar con claridad las dinámicas internas de los movimientos sociales contemporáneos, considerando la acción colectiva feminista “Ni Una Menos” en Argentina, particularmente cuatro de sus dimensiones: (1) sociopolítica, (2) estructural, (3) estratégica y (4) cultural. Para ello se incorporan algunas perspectivas de las diferentes teorías de la movilización social; se revisan los postulados centrales del feminismo materialista francés, la teoría queer y el feminismo decolonial; y se reflexiona sobre las estrategias, los repertorios de acción y los marcos de la movilización, haciendo énfasis en las gramáticas de la vida pública que se implementan en los últimos. Con todo, se busca reforzar el vínculo entre la comprensión y práctica de la protesta social.
Minería y desplazamiento: el caso de la multinacional Cerrejón en Hatonuevo, La Guajira, Colombia (2000-2010), “Nuestra tierra es nuestra vida”
Authors: Hernández Edwin
Published: August 2018

El departamento de La Guajira desde los años noventa, cuenta con la mina a cielo abierto más grande del mundo (El Cerrejón), por lo cual el Estado colombiano ha recaudado 1.461 millones de dólares por concepto de regalías en los últimos 25 años. En este artículo se plantea la importancia de resaltar la reparación a las víctimas del desplazamiento a causa de intereses económicos. Por esta razón, el artículo tendrá los siguientes subtemas: primero, se hace un recuento del descubrimiento de carbón en la región y se describe la llegada de las empresas multinacionales (BHP, Anglo American y Xstrata); segundo, se contextualiza en qué situación se encontraban los pobladores de Tabaco, antes, durante y después del desplazamiento (2002-2010), teniendo en cuenta que esta región hay presencia de comunidades indígenas Wayuu y afrodescendientes; tercero, se analiza el impacto que tiene en los habitantes de Tabaco el desplazamiento, el desarraigo, la ruptura del tejido social y los daños ambientales; por último, se plantean las conclusiones de la investigación.
Iniciativas locales de paz: tres casos desde la resistencia civil para la reflexión
Authors: Mahecha Jimena
Published: August 2018

Con el fin de determinar los aportes en términos de construcción de paz que tienen algunas manifestaciones de resistencia civil, este artículo busca aproximarse al significado de las iniciativas locales de paz en Colombia a partir del análisis de tres casos concretos: la Asociación Campesina Integral del Atrato, la Comunidad de Paz de San José de Apartadó y la Asamblea Municipal Constituyente de Mogotes. Además, muestra cómo las iniciativas configuran una nueva forma de construcción de paz posliberal, surgida de un giro hacia lo local que se desarrolla en la cotidianidad y que a su vez cuestiona el papel del Estado como el actor legítimo y monopólico en un escenario de posconflicto.
En busca de inteligencia estratégica: cuatro factores para el nacimiento y evolución de una inteligencia civil colombiana
Authors: Venegas Álvaro José
Published: August 2018

El artículo presenta un avance parcial de los factores claves de la teoría del nuevo institucionalismo con la aplicación de cuatro factores planteados por Amy Zegart: los grupos de interés, el tipo de trabajo secreto de la inteligencia, los asuntos externos –potestad presidencial– y la interconexión burocrática. ¿Qué factores de los cuatro favorecen el diseño y la evolución de una inteligencia civil estratégica e independiente, partícipe en la política exterior? Se puede anticipar una respuesta negativa debido a la complejidad del entorno en el que actúan los grupos de interés, el caracter secreto de la función, la influencia del poder Ejecutivo y la ausencia de articulación de la inteligencia civil con organismos homólogos. Sin embargo, existen –aún sin consolidarse– alternativas factibles para el desarrollo de una inteligencia civil, con un cuerpo consultivo independiente que atienda los desafíos emergentes de la Inteligencia Estratégica (IE) y la política exterior.
Balance de la aplicación de la política pública de restitución de tierras en territorios colectivos: el pacífico colombiano
Authors: Ramírez Camilo
Published: August 2018

El programa de restitución de tierras en Colombia es el eje principal de una política pública que busca reversar el despojo y la usurpación de propiedades causados en el contexto del conflicto armado. En medio de las profundas desigualdades y daños que causó la violencia, la posibilidad de restituir territorios colectivos a grupos étnicos es una apuesta necesaria en el camino de construir una sociedad democrática. Este artículo presenta un balance de la implementación de este programa en la región del pacífico y describe las principales tensiones alrededor del uso y acceso a la tierra que son resueltos en las sentencias de restitución. Basado en el análisis de dos casos concretos, se evidencian los avances y dificultades en el cumplimiento de las órdenes de dichas sentencias en los departamentos de Chocó y Cauca.
Schedler, A. (2016). La política de la incertidumbre en los regímenes electorales autoritarios. Ciudad de México: Fondo de Cultura Económica, 279 pp.
Authors: Cruz Edwin
Published: August 2018

En esta obra el politólogo austriaco Andreas Schedler, actualmente profesor de la División de Estudios Políticos del Centro de Investigación y Docencia Económica (CIDE) en México, sintetiza buena parte de sus hallazgos después de una década de investigación sobre el autoritarismo electoral. El libro está compuesto por cuatro capítulos: en el capítulo I, el autor desarrolla su concepción de la política de la incertidumbre en los regímenes electorales autoritarios; seguidamente, en el Capítulo II, describe las configuraciones institucionales de los regímenes no democráticos modernos, situando en ese contexto el autoritarismo electoral; en el capítulo III, estudia el menú de la manipulación electoral en estos regímenes; y en el capítulo IV, examina la lógica de las elecciones autoritarias.
Allen, J. y Parnes, A. (2017). Shattered. Inside Hillary Clinton’s Doomed Campaign. New York, NY: Crown, 464 pp.
Authors: Calleros Héctor
Published: August 2018

Sobre la espiral destructiva en la que se encuentran los Estados Unidos, resulta necesario revisar cómo este país llego a tal escenario. El libro Shattered. Inside Hillary Clinton´s Doomed Campaign narra cómo una victoria anticipada se convirtió en una derrota inesperada de Hillary Clinton.
Comentario a Carney, P. y Weible, C. (2018). Las nuevas ciencias de política pública: combinando la ciencia cognitiva de la decisión, las múltiples teorías del contexto y el análisis básico y aplicado (Trads. J. G. Vieira y S. Olis). Ciencia Política, 13(26), 321-338.
Authors: Roth André-Noël
Published: August 2018

El llamado a imaginar unas nuevas ciencias de la política pública por parte de dos destacados académicos como Paul Cairney y Christopher Weible constituye un hito significativo para este campo de estudio; razón por la cual su traducción y publicación es importante para permitir la difusión de los debates internos al campo en el ámbito latinoamericano. Los autores consideran que se necesita de una nueva “visión” para enfrentar los desafíos actuales del campo de estudio de las políticas públicas, y lograr los propósitos que había planteado Lasswell en 1956, es decir, “el progreso de la sociedad y la realización de una mayor dignidad humana, particularmente enfocadas hacia los ideales democráticos”.
Presentación
Authors: Jiménez Carolina
Published: August 2018

Las luchas sociales por el reconocimiento de los derechos han condu­cido a procesos de ampliación democrática de los Estados Nacionales. En efecto, la posibilidad de avanzar hacia la construcción de órdenes sociales más justos e incluyentes, encuentran una fuerza vital en las ac­ciones y dinámicas organizativas de hombres y mujeres, que demandan al Estado la producción de normas y políticas públicas que promuevan, por una parte, la ampliación y el ejercicio de los derechos, y por la otra, la materialización de las agendas sociales de la diversidad de sujetos políticos presentes en la sociedad en un momento histórico específico.
GOATFISH (MULLIDAE) RESOURCES IN VIETNAM SEA BASED ON BOTTOM TRAWL SURVEY IN THE PERIOD 2012 - 2013
Authors: Thang Vo Trong , Cuong Tran Van , Nhuan Mai Cong , Hai Nguyen Van
Published: August 2018

During 2012 - 2013, under the project “The current status and movements of fisheries resources in Vietnam sea” two surveys were conducted to investigate bottom fish resources with 494 hauls. Based on the research results, 16 species belonging to 3 genera of goatfishes were analyzed. The goatfish output accounted for 0.34 - 4.31% compared to the total output of bottom fish in the survey time. The species Upeneus japonicus comprised 62 - 94% of the output of the goatfishes. The average exploitation yield of goatfishes in the Northeast monsoon season was 1.035 kg/h and that in the Southwest monsoon season was 1.446 kg/h. The exploitation yield had a tendency of decrease compared with the previous studies. The distribution density was the highest in the Southwestern region areas and the lowest in the Gulf of Tonkin; Meanwhile according to spatial distribution the density of goatfishes was the highest in the depth < 20 m and the lowest in the depth from 30 - 50 m. The estimation for the total biomass of goatfishes in the Northeast monsoon season was 13,450 tons and in the Southeast monsoon season was 15,321 tons.
XÂY DỰNG KHUNG CƠ SỞ DỮ LIỆU SỐ VỀ HẢI DƯƠNG, MÔI TRƯỜNG VÙNG BIỂN NINH THUẬN - BÌNH THUẬN
Authors: Tien Ngo Manh , Huan Nguyen Huu , Chung Tran Van , Son Tong Phuoc Hoang , Thach Vo Trong , Thuy Pham Thi Thu
Published: August 2018

This paper presents the building and designing of the digital database frame about the oceanographic and environmental elements of the coastal waters of Ninh Thuan and Binh Thuan provinces, based on the integration of data from the observed, multi-temporal remote sensing as well as simulated sources. Especially, VNREDSat-1 the first remote sensing imagery of Vietnam with high resolution also got the attention in building the digital database frame. The building of the digital database frame is the first important step in order to achieve an overview of data’s structure, then to build the database’s structure. The database’s structure is built in the form of B-tree which optimize the operation when updating the data.
KHẢ NĂNG KHÁNG KHÁNG SINH CỦA VI KHUẨN BIỂN TẠI HÒN MỘT VỊNH NHA TRANG
Authors: Mien Pham Thi , Ha Dao Viet , Hanh Nguyen Kim
Published: August 2018

Drug resistance is now an issue of deep scientific concern all over the world as more antibiotic resistant bacteria have been detected in many regions and countries in recent years. Using of antibiotics for aquaculture is quite common in developing countries including Vietnam. This causes the spread of antibiotic resistant bacteria in the environment. Testing of antibiotic resistant bacteria was carried out in commercial marine aquaculture and tourist zones in Hon Mot in the Nha Trang bay with five different antibiotics namely chloramphenicol, tetracycline, cefazolin, streptomycin, and gentamicin on Mueller Hinton Agar. A total of 18 strains composed of 14 Gram positive strains, 4 Gram negative strains were tested for antibiotic resistance. Strain KH1 showed the least sensitive to tetracycline with average radius of 4.0 mm, while strain T1 showed the least sensitive to streptomycin with average radius of 4.2 mm. The strains KH6 and T7 showed resistance to cefazolin with radius of inhibition zone of 0 mm and 2 mm, respectively. The strain KH6 was confirmed as Bacillus sp. Antibiotic resistant bacteria were now found in Nha Trang bay, so there may be additional resistant bacteria, even multi-antibiotic resistant bacteria outside the marine environment. This is a matter for further research that should provide solutions to limit the rise of antibiotic resistant bacteria.
A research on the performance of down-flow hanging sponge (DHS) reactor treating domestic wastewater
Authors: Nguyen Hiep Trung , Le Hong Tuyet Thi , Dinh Nga Thi , Phan Tuan Dinh
Published: August 2018

The aim of this study was to evaluate the performance of a down-flow hanging sponge (DHS) system in treating domestic wastewater. A pilot-scale of DHS system with a capacity of 60 L was designed and fabricated from polyvinyl chloride (PVC). The dimensions of DHS system are 1.5 m in height and square surface with 0.2 m in width, consists of three identical segments connected vertically in series. Each segment was filled by polyurethane sphere containing sponge. The total area of sponge and polyurethane sphere was 3,300 m2 m-3, density at 150 kg m-3, void ratio at 90%. DHS system was operated at ambient temperature within 82 days and stepwise increased of organic f rate from 0.5 to 1 and 1.5 kg COD m-3 d-1. The results showed that, this system performed well throughout the operational period and achieve the maximum removal of COD, BOD5, NH4+-N, and TN as 80%, 83%, 65% and 60%. The effluent of wastewater from DHS system achieved the requirement for National technical regulation on domestic wastewater of Vietnam type B QCVN 14:2008/BTNMT. In conclusion, the performance of DHS system indicated a high potential for application in removing organic matter and converting nitrogen ammonia to nitrogen nitrate, however it did not perform well for the removal of total nitrogen, it is necessary to study further by providing an anoxic zone in the system to enhance the treatment of nutrient in wastewater.
Evaluating the influence of grinding mode on part’s accuracy and grinding wheel’s wear in grinding profile for ball bearing's inner ring groove
Authors: Tuan Nguyen Anh , Thang Vu Toan , Tiep Nguyen Viet
Published: August 2018

Determining the influence of technological mode factors on machining accuracy is always an current issue in the production practice especially for grinding operations. This paper presents some research results to determine the effect of grinding parameters on grinding wheel’s wear and part’s accuracy in grinding profile for ball bearing's inner ring groove. From theoretical analysis and experimental results, the article assesses the influence of grinding mode factors on output factors. Based on that, the economic limitation wear of grinding wheel at three different grinding modes is determined.
Mini-Review PROTEASE INHIBITOR (PI) AND PIs FROM SPONGE-ASSOCIATED MICROORGANISMS
Authors: Hong Tran Thi , Dat Ton That Huu , Cuc Nguyen Thi Kim , Cuong Pham Viet
Published: August 2018

Protease inhibitors (PIs) are proteins or peptides inhibiting the activity of protease and constitute a very important mechanism for regulating protease activity. So far, PIs have been used for the study of enzyme structures and reaction mechanisms, but recently they have been used in pharmaceutical, agricultural and industrial fields. Compared to terrestrial counterparts, marine environment possesses their unique characters, therefore, they are capable of producing a wide range of novel bioactive compounds including protease inhibitors. In our review, a brief overview of protease inhibitors (e.g., classification, mechanisms, and characteristics of PIs) and protease inhibitors from marine sponges and sponge-associated microorganisms has been reviewed.
SYNTHESIS AND CYTOTOXICITY OF POLYHYDROXYLATED CHOLESTEROL DERIVATIVES
Authors: Tran Thu Thuy Thi , Dinh Ha Thi , Doan Phương Lan , Pham Long Quoc , Ngo Quang Dai
Published: August 2018

Eight polyhydroxylated cholesterol derivatives (1-8) were prepared from cholesterol, using oxidative reagents as SeO2, OsO4/NMO, HCOOH/H2O2 and BH3/ H2O2. Their structures were elucidated by using physical methods including NMR 1D and 2D. These compounds were evaluated against two cancer cell lines (Hep-G2, T98). Compounds 2, 4 and 8 inhibits human hepatocellular carcinoma cell line (Hep-G2) with IC50 4.69, 4.98 and 2.89 µg/mL, respectively. In addition, compound 8 exhibited strong cytotoxicity against T98 cell line (glioblastoma) with IC50 = 2.28 μM.
O-hydroxybenzaldehyde rich leaf essential oil composition of Filipundula vestita Wall.Ex G.Don from western Himalaya of Uttrakhand, India
Authors: Joshi Rakesh Kumar
Published: August 2018

O-hydroxybenzaldehyde or salicylaldehyde has many applications as an intermediate in chemical industries. Genus Filipendula is a potential source of salicycldehyde. Essential oils are prescribed for a variety of health problems by traditional systems of medicine, all over the world. In present study, leaf essential oil composition of Filipendula vestita Wall.Ex G.Don (Family: Rosaceae) from India was analyzed using gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS) methods. The volatile extract was dominated by salicylaldehyde 51.5%, methyl salicylate 24.5%, salicylic acid butyl ester 5.70%, carvone 4.30%, santene 3.50%, as major constituents.
CONTENTS
Authors: Contents Contents
Published: August 2018

Contenst, Vol. 56, N. 4 (2018)
Outcome of First-Line Systemic Treatment for Unresectable Conventional, Dedifferentiated, Mesenchymal, and Clear Cell Chondrosarcoma
Authors: van Maldegem Annemiek , Conley Anthony P. , Rutkowski Piotr , Patel Shreyaskumar R. , Lugowska Iwona , Desar Ingrid M.E. , Bovée Judith V.M.G. , Gelderblom Hans
Published: August 2018

Background

Chondrosarcoma is a heterogeneous group of primary bone sarcoma with an excellent overall survival after local therapy. However, the small percentage of patients who have no surgical treatment options have a very poor prognosis. We retrospectively collected data from these patients in four sarcoma centers and compared the progression-free survival (PFS) for the different treatment regimens used for the four chondrosarcoma subtypes.

Materials and Methods

Patients diagnosed with unresectable chondrosarcoma in all four major sarcoma centers were included, and data on first-line systemic therapy were retrospectively collected for analysis.

Results

A total of 112 patients were enrolled in this retrospective analysis: 50 conventional, 25 mesenchymal, 34 dedifferentiated, and 3 clear cell chondrosarcoma patients. In conventional chondrosarcoma patients, the longest mean PFS (6.7 months) was found in the group treated with antihormonal therapy. Patients diagnosed with mesenchymal chondrosarcoma were all treated with multidrug chemotherapy, and the mean PFS was 6.7 months. Doxorubicin monotherapy seems to have an unexplained better PFS than doxorubicin-based combination therapy in patients with dedifferentiated chondrosarcoma (5.5 vs. 2.8 months, respectively; p = .275).

Conclusion

Prospective studies need to be conducted based on preclinical work to develop a uniform regimen to treat advanced chondrosarcoma patients according to the diagnosed subtype and improve survival.

Implications for Practice

Currently, there are no uniform treatment lines for advanced chondrosarcoma patients, which results in a very diverse group of treatment regimens being used. In this study, the data of 112 patients was collected. It was concluded that some treatment regimens seem to have a better progression-free survival compared with others, and that these results also differ between the chondrosarcoma subtypes. Prospective studies need to be conducted based on preclinical work to develop a uniform regimen to treat advanced chondrosarcoma patients according to the diagnosed histological subtype to improve their survival.