bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN ARSITEKTUR MODERN PADA BANGUNAN DI KAWASAN REST AREA ‎MOLOSIPAT KABUPATEN POHUWATO
Authors: Syukri Muhammad Rijal , Idji Berni , Utina Sunarto
Published: August 2023

Rest area merupakan salah satu fasilitas yang mendukung mobilitas bagi pengendara bermotor, namun di Provinsi Gorontalo belum ada Rest Area yang menunjang secara standar yang digunakan oleh pemerintah. Rest area selain fasilitas penunjang mobilitas, juga sebagai tempat beristirahat bagi pengendara untuk memulihkan tenaga dan juga melakukan berbagai aktivitas lainnya, diantaranya makan/minum, beribadah, belanja kebutuhan, dan terutama mengisi bahan bakar kenderaan. Tujuan perancangan Rest Area adalah untuk mendesain kawasan Rest Area dengan fasilitas yang memadai sesuai standar yang ditetapkan oleh pemerintah. Hasil penelitian menunjukkan bahwa bentuk pada desain rest area Molosipat merupakan transformasi dari bentuk Burung Maleo dengan susunan ruang dan pola sirkulasi terpusat. Struktur yang digunakan merupakan material beton bertulang dan penambahan secondary skin berbahan Alumunium Composite Panel (ACP) ataupun kayu laminasi.
PENERAPAN PENDEKATAN ARSITEKTUR METAFORA PADA PERANCANGAN PUSAT PEDIDIKAN DAN PELATIHAN BOLA VOLI DI GORONTALO
Authors: Rauf Fikri Yanto , Idji Berni , Syukri Muh. Rijal
Published: August 2023

ABSTRAKOlahraga bola voli merupakan salah satu olahraga populer di Provinsi Gorontalo. Kepopuleran olahraga bola voli yang ada di Gorontalo ditandai dengan berkembangnya berbagai klub bertaraf lokal seperti di desa sampai yang bertaraf daerah. namun, gedung olahraga tertutup (indoor) di Gorontalo hanya Gor Nani Wartabone dan Gor David Tony Limboto. Provinsi Gorontalo pada tahun 2019 pernah menjadi tuan rumah babak kualifikasi Pra PON XX.Teori metafora konkrit dipilih karena metafora jenis ini dapat menggambarkan pesan dalam bentuk tiga dimensi secara jelas. Hal ini dikarenakan sudah sesuai dengan permasalahan perancangan pusat pendidikan dan pelatihan bola voli yaitu rancangan bangunan yang dapat mempengaruhi semangat para atlet. Metode yang digunakan dalam penyusunan adalah metode pengolahan data kualitatif.banyaknya event yang pernah dilaksanakan di Provinsi Gorontalo antara lain Kualifikasi Pra PON XX, Walikota Gorontalo Cup, Invitasi Gala Tua Gorontalo, Turnamen Mavi-Go, Turnamen bola voli RAPI BONBOL Cup, Piala Danrem 133/Nani Wartabone, Turnamen Bupati Bone Bolango Cup ke-6, Turnamen Kapolda Cup, Bupati Pohuwato Cup, Limbers Cup Gorut, Turnamen Bola Voli Bupati Gorontalo Cup II dan Marten Taha Cup Kota Gorontalo. pengambilan objek pusat pendidikan dan pelatihan bola voli ini merupakan hasil dari survei yang mana rata-rata pemain/atlet bola voli yang sering mengikuti kegiatan tingkat daerah ataupun nasional masih berstatus sebagai siswa di sekolah sehingga kegiatan belajar mengajar siswa tersebut masih terganggu dengan kegiatan ekstrakurikuler sekolah. pemilihan objek pusat pendidikan dan pelatihan bola voli ini dimaksudkan sebagai tempat yang mampu mewadahi permasalahan tersebut.
PERANCANGAN SANATORIUM DI GORONTALO DENGAN PENDEKATAN ARSITEKTUR MODERN FUNGSIONALIS
Authors: Lasalewo Rio Vahlevi Noor Zulkifli , Siola Amru , Tamrin Moh Muhrim
Published: August 2023

Countering the spread of Tuberculosis disease in Gorontalo is still very low and slow in service.  This is due to the lack of health support facilities specifically for Tuberculosis disease. According to the 2018 Case Detection Rate, Gorontalo Province ranks 6th as the province with the highest spread of Tuberculosis in Indonesia.  Based on the number of all Tuberculosis case records per 100,000 population, Gorontalo Province ranks 4th among 34 other provinces in Indonesia, after DKI Jakarta, South Sulawesi, and Papua.  The construction of sanatorium buildings is prioritized to be built in distant areas with minimal population. It is intended that the spread of Tuberculosis disease can be reduced and sufferers can recover faster.  The right design analysis to adjust the needs of sanatorium building users is to use the functionalist modern architecture design approach.  Through this approach, the function of the building becomes a reference in the design process so that it can meet the needs of the building users, namely both patients and managers.Penanggulangan penyebaran penyakit Tuberculosis di Gorontalo masih sangat minim dan lambat pelayanannya, hal tersebut dikarenakan kurangnya fasilitas penunjang kesehatan khusus penyakit Tuberculosis. Menurut Case Detection Rate tahun 2018, Provinsi Gorontalo menempati peringkat ke-6 sebagai provinsi dengan penyebaran Tuberculosis tertinggi di Indonesia, sedangkan menuru tangka semua notifikasi kasus Tuberculosis per 100.000 penduduk, Provinsi Gorontalo menempeti peringkat ke-4 diantara 34 provinsi lain di Indonesia, setelah DKI Jakarta, Sulawesi Selatan, dan Papua. Pembangunan bangunan sanatorium di prioritaskan di bangun di daerah jauh penduduk yang minim populasi, hal tersebut ditujukan agar penyebaran penyakit Tuberculosis dapat berkurang dan para penderita dapat sembuh lebih cepat. Analisis perancangan yang tepat untuk menyesuaikan kebutuhan pengguna bangunan sanatorium adalah dengan menggunakan pendekatan perancangan Arsitektur Modern Fungsionalis, dimana dalam pendekatan ini, fungsi dari bangunan yang menjadi acuan dalam proses perancangan, sehingga dapat memenuhi kebutuhan-kebutuhan pengguna bangunan, baik pasien dan pengelolanya.
The Potential of Flutter-Based Windbelt for Energy Generation in Low-Wind-Speed Regions: A Case Study in Malaysia
Authors: Nurul Mardhiyah Zakaria  , Muhammad Shahmi Zulkifli  , Azfarizal Mukhtar
Published: August 2023

The need to reduce carbon emissions from conventional electricity generation has led to research into alternative renewable energy solutions, including wind energy. However, conventional wind turbines are not practical in Malaysia due to their size, cost and low wind speeds. Therefore, recent research has focused on the development of small wind energy generation systems, such as wind-induced vibratory devices, for small-scale power generation. This study aims to enhance the design parameters of a flutter-based windbelt with an electromagnetic conversion mechanism specifically tailored to optimise the use of low wind speeds in Malaysia. Various factors such as wind speed, wind direction, magnet position, magnet size and device length were studied to understand their influence on energy generation. The study conducted experiments in controlled and uncontrolled environments, with the latter chosen in a location known for its high wind potential. Five experiments were conducted and measurements were taken three times to ensure accuracy of the data. The results showed that wind speed and magnet size were positively correlated with voltage generation, while wind direction and magnet coil position had more complex relationships. These results contribute to a better understanding of windbelt performance and identify opportunities to optimise windbelt design and placement. Future research could further investigate factors such as turbulence and find ways to integrate the wind belt into more significant devices.
Numerical Investigation of Heat Transfer Enhancement of Al2O3 Nanofluid in Microchannel Heat Sink
Authors: Allison Soundrapaman  , Normayati Binti Nordin  , Abdoulhdi A. Borhana Omran  , Abdulhafid M A Elfaghi
Published: August 2023

This study focusses on using computational fluid dynamics (CFD) to study the enhancement of heat transfer from the use of AL2O3 nanofluid in a microchannel heat sink (MCHS) to develop a more efficient cooling device for high-power integrated circuits. The objective is to investigate the heat transfer performance, parameters, and enhancement rate using Ansys Fluent software, and to compare the results with experiments to show the effectiveness of this method. This study will also focus on the relationship between the friction fraction and nanoparticles volume fraction to improve the heat transfer enhancement in the MCHS. The temperature, pressure, heat transfer coefficient, Nusselt number, and friction coefficient are analysed in this study. The results showed that an increase in the volume fraction of the nanofluid leads to an increase in the average heat transfer coefficient. The results showed that for 4% nanofluid volume concentration, the Nusselt Number has improved by 10% compared to pure water. However, an increase in volume concentration also resulted in an increase in pressure drop.
Stagnation Bioconvection Flow of Titanium and Aluminium Alloy Nanofluid Containing Gyrotactic Microorganisms over an Exponentially Vertical Sheet
Authors: Siti Khuzaimah Soid  , Siti Nor Asiah Ab Talib  , Nur Hazirah Adilla Norzawary  , Siti Suzilliana Putri Mohamed Isa  , Muhammad Khairul Anuar Mohamed
Published: August 2023

The pivotal aim of this research is to address a natural stagnation bioconvection flow of a hybrid nanofluid containing gyrotactic microorganisms over an exponentially stretching and shrinking vertical sheet. The mathematical formulation of simplified Navier-Stokes equations is made in the presence of a few parameters such as Prandtl number, concentration to thermal buoyancy ratio, microorganism to thermal buoyancy ratio, Lewis number, bioconvection Peclet number, bioconvection Lewis number, microorganisms concentration difference and buoyancy parameter. The two types of nanofluid containing titanium alloy (Ti6Al4V) and aluminium alloy (AA7075) immersed in water are considered for the investigation. In the analysis, the governing partial differential equations (PDEs) are transformed into a set of ordinary differential equations (ODEs) by a similarity transformation. The resulting equations are rewritten in MATLAB software through the Bvp4c method to obtain the solutions. The effects of hybrid nanofluid of titanium alloy (Ti6Al4V) and aluminium alloy (AA7075), microorganisms’ concentration difference parameter, and bioconvection Lewis Number are observed in this mathematical model in the presence of stretching and shrinking sheets. The numerical values are obtained for the skin friction coefficient, local Nusselt number, local Sherwood number, and local density of motile microorganisms for the reporting purpose. In addition, the profiles of the velocity, temperature, concentration, and microorganism are visualized as the main findings of this article.
A Contemporary Review of High Voltage Partial Discharge Detection and Recognition Techniques
Authors: Zul Hasrizal Bohari  , Muzamir Isa  , Faizah Abu Bakar  , Ahmad Zaidi Abdullah  , Ayob Nazmy Nanyan  , Mohamad Na’im Mohd Nasir  , Mohamad Fani Sulaima  , Emy Zairah Ahmad
Published: August 2023

This review article provides a summary of the most advanced approaches and advancements in the detection and recognition of high voltage partial discharge (PD). It discusses numerous detecting technologies, such as electrical, acoustic, and optical approaches, as well as their merits and disadvantages. It also discusses current developments in signal processing and pattern recognition algorithms used for PD detection and classification. Lastly, the study covers the challenges and limitations in high voltage PD detection and identification studies, as well as potential future solutions.
ОБУЧЕНИЕ НАВЫКАМ МЕДИАЦИИ И ПРИМИРИТЕЛЬНЫХ
ПРОЦЕДУР КАК НОВОЕ ПРАКТИКО-ОРИЕНТИРОВАННОЕ
НАПРАВЛЕНИЕ ОБУЧЕНИЯ В ЮРИДИЧЕСКОЙ КЛИНИКЕ
Authors: Балашова И. Н. , Менжега М. М.
Published: August 2023

В настоящей статье авторы исследуют особенности формирования профессиональных навыков медиации у будущих юристов на базе юридической клиники ФГБОУ ВО «Саратовская государственная юридическая академия». Юридическая клиника представляет собой одну из форм организации образовательного процесса, сущность которой состоит в закреплении на практике полученных теоретических навыков. Рассматривается аспект важности обучения студентов правилам примирительных процедур в досудебном решении конфликтных ситуаций.
ИНФРАСТРУКТУРНЫЕ ОБЯЗАТЕЛЬСТВА ГОСУДАРСТВА ПО ВНЕДРЕНИЮ ЭЛЕМЕНТОВ ЭЛЕКТРОННОГО ПРАВОСУДИЯ
Authors: Егорцова И. В. , Забелина К. Е. , Соколова О. В.
Published: August 2023

В настоящей статье рассматривается проблема электронно-цифрового государства и правосудия. Внедрение новых цифровых технологий в судебную систему, а также эффективности деятельности уже существующих инфраструктурных обязательств государства по внедрению элементов электронного правосудия, и прогнозирования введения модификационных технологий.
ТАЙНА УСЫНОВЛЕНИЯ В ГРАЖДАНСКОМ ПРОЦЕССЕ
Authors: Стрельникова Д. А. , Янко Е. А. , Соколова О. В. Соколова В.
Published: August 2023

В статье определяется понятие тайны усыновления, рассматриваются правовые по-ложения законодательства Российской Федерации о тайне усыновления, а также анализируется совокупность сведений, которые составляют тайну усыновления в России; анализируются научные точки зрения на вопрос сохранения данной тайны, высказывается мнение о внесении изменений в законодательство России, регулирующее тайну усыновления.
УТИЛИТАРНЫЕ ЦИФРОВЫЕ ПРАВА:
ВИДЫ И ПОРЯДОК ОБРАЩЕНИЯ
Authors: Певцова И. Е.
Published: August 2023

В статье рассматривается новый способ привлечения инвестиций через предложение утилитарных цифровых прав. Раскрываются особенности правового регулирования утилитарных цифровых прав, порядок их обращения. Охарактеризованы осуществление и оборот утилитарных цифровых прав, выявлены их специфические черты и содержание.
High-resolution SOFIA/EXES Spectroscopy of Water Absorption Lines in the Massive Young Binary W3 IRS 5
Authors: Li 李 Jialu 佳璐 , Boogert Adwin , Barr Andrew G. , DeWitt Curtis , Rashman Maisie , Neufeld David , Indriolo Nick , Pendleton Yvonne , Montiel Edward , Richter Matt , Chiar J. E. , M. Tielens Alexander G. G.
Published: August 2023

We present in this paper mid-infrared (5–8 μm) spectroscopy toward the massive young binary W3 IRS 5, using the Echelon Cross Echelle Spectrograph (EXES) spectrometer in high-resolution mode (R ∼ 50,000) from the NASA Stratospheric Observatory for Infrared Astronomy (SOFIA). Many (∼180) ν
2 = 1–0 and (∼90) ν
2 = 2–1 absorption rovibrational transitions are identified. Two hot components over 500 K and one warm component of 190 K are identified through Gaussian fittings and rotation diagram analysis. Each component is linked to a CO component identified in the IRTF/iSHELL observations (R = 88,100) through their kinematic and temperature characteristics. Revealed by the large scatter in the rotation diagram, opacity effects are important, and we adopt two curve-of-growth analyses, resulting in column densities of ∼1019 cm−2. In one analysis, the model assumes a foreground slab. The other assumes a circumstellar disk with an outward-decreasing temperature in the vertical direction. The disk model is favored because fewer geometry constraints are needed, although this model faces challenges as the internal heating source is unknown. We discuss the chemical abundances along the line of sight based on the CO-to-H2O connection. In the hot gas, all oxygen not locked in CO resides in water. In the cold gas, we observe a substantial shortfall of oxygen and suggest that the potential carrier could be organics in solid ice.
Modulation of Cosmic-Ray Antiprotons in the Heliosphere: Simulations for a Solar Cycle
Authors: Aslam O. P. M. , Potgieter M. S. , Luo 罗 Xi 熙 , Ngobeni M. D.
Published: August 2023

The precision measurements of galactic cosmic-ray protons from the Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics and the Alpha Magnetic Spectrometer are reproduced using a well-established three-dimensional numerical model for the period 2006 July–2019 November. The resulting modulation parameters are applied to simulate the modulation for cosmic antiprotons over the same period, which includes the times of minimum modulation before and after 2009, the maximum modulation from 2012 to 2015, including the reversal of the Sun’s magnetic field polarity, and the approach to new minimum modulation in 2020. Apart from their local interstellar spectra, the modulation of protons and antiprotons differ in their charge sign and consequent drift pattern. The lowest proton flux was in 2014 February–March, but the lowest simulated antiproton flux is found to have been in 2015 March–April. These simulated fluxes are used to predict the proton-to-antiproton ratios as a function of rigidity. The trends in these ratios contribute to clarifying, to a large extent, the phenomenon of charge-sign dependence of heliospheric modulation during vastly different phases of the solar activity cycle. This is reiterated and emphasized by displaying so-called hysteresis loops. It is also illustrated how the values of the parallel and perpendicular mean free paths, as well as the drift scale, vary with rigidity over this extensive period. The drift scale is found to be at its lowest level during the polarity reversal period, while the lowest level of the mean free paths is found to be in 2015 March–April.
Impact Rates in the Outer Solar System
Authors: Nesvorný David , Dones Luke , De Prá Mario , Womack Maria , Zahnle Kevin J.
Published: August 2023

Previous studies of cometary impacts in the outer solar system used the spatial distribution of ecliptic comets (ECs) from dynamical models that assumed ECs began on low-inclination orbits (≲5°) in the Kuiper Belt. In reality, the source population of ECs—the trans-Neptunian scattered disk—has orbital inclinations reaching up to ∼30°. In Nesvorný et al., we developed a new dynamical model of ECs by following comets as they evolved from the scattered disk to the inner solar system. The model was absolutely calibrated from the population of Centaurs and active ECs. Here we use our EC model to determine the steady-state impact flux of cometary/Centaur impactors on Jupiter, Saturn, Uranus, and their moons. Relative to previous work, we find slightly higher impact probabilities on the outer moons and lower impact probabilities on the inner moons. The impact probabilities are smaller when comet disruption is accounted for. The results provide a modern framework for the interpretation of the cratering record in the outer solar system.
Three new species of the Neotropical genus Smilidarnis Andrade (Hemiptera, Membracidae)
Authors: McKamey Stuart H.
Published: August 2023

Smilidarnis duocornussp. nov., S. erwinisp. nov., and S. robustussp. nov. are described, illustrated, and included in a key to the five species here recognized in Smilidarnis. One member of this genus, from Ecuador (new country record for genus), is S. erwini, which differs from its congeners in having distinct coloration and being of intermediate size in terms of overall body length and the relative length of the lateral apical spines. Smilidarnis robustus (from Peru) and S. duocornus (from Brazil) differ from the other species of Smilidarnis in having the pronotum bearing a pair of suprahumeral spines.
The larval, pupal and mitogenomic characteristics of Agrilus adelphinus Kerremans, 1895 (Coleoptera, Buprestidae) from China
Authors: Huang Xuyan , Gan Yujie , Wang Lei , Xu Yanying , Wei Zhonghua , Shi Aimin
Published: August 2023

In this study, the larva and pupa of Agrilus adelphinus are described and illustrated. DNA barcoding (COI gene) was used to associate the larval and pupal stages with adults based on the maximum-likelihood method. In the resulting phylogenetic tree, species from the same species-group were found to be clustered on a branch with high support value. To better understand A. adelphinus, the complete mitochondrial genome of this species was also sequenced and annotated. Comparing this genome to the known mitogenomes of Agrilus species, the newly sequenced genome is shorter, with 15,732 bp. However, its whole mitogenome composition and gene orientation were consistent with that of most species of Buprestidae. In the mitogenome of A. adelphinus, the ATGATAG sequence was observed between ATP8 and ATP6, which is ATGATAA in other insect mitogenomes. Leu2, Phe, Ile, Gly, and Ser2 were the five most frequently encoded amino acids. The results further prove that DNA barcoding can remove the limitation of traditional taxonomy which cannot identify to species all developmental stages. This study also provides valuable molecular and morphological data for species identification and phylogenetic analyses of the genus Agrilus.
Treatment in Children and Adolescents With Obsessive-Compulsive Disorder: Review for Practitioners
Authors: Ramos-Marcuse Fatima , Kverno Karan
Published: August 2023

Obsessive-compulsive disorder (OCD) is one of the most debilitating mental health conditions, interrupting functioning at school and social well-being in children and adolescents. Youth tend to delay interventions and when sought, response to treatment might not be optimal. The current article discusses treatment guidelines for youth with OCD and pediatric autoimmune neuropsychiatric symptoms. [
Journal of Psychosocial Nursing and Mental Health Services, 61
(8), 11–15.]
Molecular and biotechnological characteristics of proteolytic activity from Streptococcus thermophilus as a proteolytic lactic acid bacteria to enhance protein-derived bioactive peptides
Authors: Phupaboon Srisan , Hashim Farah J. , Phumkhachorn Parichat , Rattanachaikunsopon Pongsak
Published: August 2023

The demand for healthy food items with a high nutrient value of bioavailability and bioaccessibility has created a need for continuous development of technology and food ingredients like bioactive peptides. This study aimed to investigate seven proteolytic lactic acid bacteria (PLABs) isolated from the plaa-som (fermented fish) sample originated from silver BARB species for production of proteolytic enzymes. Proteolytic enzymes produced by (PLABs) were used further to create potent bioactive peptides by hydrolyzing proteins throughout PLAB-probiotics enhancer. Protein derived-bioactive peptides was tested the proteolytic activity on different protein sources and examined bioactivities including antioxidative and antimicrobial effect for further use in functional foods. Results of screened-PLAB strains showed high proteolytic activity namely Streptococcus thermophilus strains (KKUPA22 and KKUPK13). These strains have proteolytic system consisting of extracellular and cell-bound enzymes that used for degrading protein in fish flesh protein (FFP) and skim milk (SKM) broth media. Proteolytic activity of tested bacterial enzymes was estimated after incubation at 45, 37, and 50 °C. Furthermore, FFP hydrolysates were formed with various peptides and has small molecular weights (checked by SDS-PAGE) in the range of10.5 to 22 kDa), exhibiting strong activity. Data revealed that S. thermophilus strains (KKUPA22 and KKUPK13) had high antioxidant activity in term of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) radical-scavenging inhibition, and ferric reducing antioxidant power (FRAP) reducing power capacity. Both strains (KKUPA22 and KKUPK13) of S. thermophilus have higher antimicrobial activity against Gram-negative bacteria than against Gram-positive bacteria. We have confirmed presence of proteolytic (prt) gene regions in S. thermophilus strains using specific primers via PCR amplification. Results showed highest homology (100%) with the prtS gene of S. thermophillus located on the cell envelope proteolytic enzymes (CEPEs) such as serine proteinase. Therefore, it concluded that the proteolytic system of tested PLAB strains able to generate bioactive peptides-derived proteins having active biological property, good mechanism of degradability, and bioaccessibility for further use in catalyzing protein of functional foods.
Float Photovoltaic Module Prototype: Design, Simulation, and Electrical Performance Analysis
Authors: Zarede Toufik , Lidjici Hamza
Published: August 2023

Photovoltaic solar energy is an abundant, renewable, and clean source of energy that can contribute to the energy transition. However, traditional land-based solar installation have limitations in terms of space, efficiency, and environmental impact. Floating solar panels have emerged as a promising technology that can overcome these limitations and provide a range of benefits. This work describes the design and experimental testing of a small-scale of floating photovoltaic module prototype, with a focus on the effect of solar irradiation on its maximum power output. The prototype is composed of a 4Wp photovoltaic module and a buoyant supporting structure. Using Matlab®, simulations were performed on the floating photovoltaic module under varying environmental conditions, including solar irradiance, temperature, and wind speed. The prototype demonstrated an electrical performance of 3.62W under solar irradiation of 895W/m2 and a temperature of 41°C, with a power ratio exceeding 97% of this maximum power under standard conditions. The prototype also showed a positive energy gain when compared to the same photovoltaic module in a horizontal or inclined position, particularly at high temperature and solar irradiance. Moreover, shows a stability and resistance in harsh weather conditions. The mathematical fitting with a Gaussian distribution shows the rapid increase of the maximum power of the floating photovoltaic module in the range of 37°C to 42°C of temperature with increasing solar irradiance.
Commission géologique du Canada bilan de l'année (rapport supplémentaire) : 2021-22
Authors: Lebel D
Published: August 2023

This report highlights the GSC's additional contribution to NRCan's core mandated responsibility, Natural Resource Science and Risk Mitigation through Geological Knowledge for Canada's Onshore and Offshore Lands; Geoscience for Sustainable Development; and
Geoscience for Keeping Canada Safe, and is a companion product to the annual report Geological Survey of Canada Year in Review: 2021-22. The mission of the GSC is to provide authoritative and cutting-edge geoscience information. This document presents a high-level corporate overview of the GSC and
its science programs and activities.
A Case Report on Catastrophic Antiphospholipid Syndrome with Cardiomyopathy
Authors: Indu M. B. , Singh Rajnish , Chawla Raghuraj
Published: August 2023

Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening disease that causes the formation of microthrombi in multiple vascular beds, leading to multiorgan dysfunction. We report an unusual case of systemic lupus erythematosus-associated CAPS that presented with left ventricular failure along with cortical venous thrombosis and thrombotic renal microangiopathy.
Aberrant Right Subclavian Artery Complicated by Acquired Hemophilia A and a Subclavian Artery–Esophageal Fistula after Traumatic Injury
Authors: Hirayu Nobuhisa , Fukuda Masafumi , Nabeta Masakazu , Takasu Osamu
Published: August 2023

An aberrant right subclavian artery (ARSA) is a rare developmental anomaly wherein the right subclavian artery arises from the descending aorta as a fourth branch of the aortic arch. We present the case of ARSA in an 81-year-old woman who was injured in a motorcycle accident. The patient had a history of asymptomatic cerebral infarction, type 2 diabetes mellitus, and rheumatoid arthritis. She was diagnosed with spleen and liver injury, left renal injury, along with fractures in the rib, pelvic, vertebrae, and right tibia. On the 3rd hospitalization day, activated partial thromboplastin time (APTT) prolongation was observed, followed by sudden massive hematemesis and shock on the 39th day. We indicate sudden hematemesis and ARSA bleeding as the cause. We performed compression with a Sengstaken–Blakemore tube and coil embolization for hemostasis. Our findings show that the bleeding was mainly caused by nasogastric tube compression, prolonged APTT, and acquired hemophilia A.
Surgical Outcome of Constrictive Pericarditis
Authors: Alshimary Yaser Abduljabbar Saleh , Alamran Fadhil Ghali , Abbas Amra Yahya
Published: August 2023

Background:

constrictive pericarditis may cause scarring and consequent loss of the normal elasticity of the pericardial sac. It is caused by idiopathic, viral, following cardiac surgery, radiation, connective tissue disorder, postinfectious (tuberculous or purulent pericarditis), or miscellaneous causes (malignancy, trauma, drug-induced, asbestosis, sarcoidosis, and uremic pericarditis). It is mostly presented by shortness of breath (SOB) due to right-sided failure. Surgical procedure is the cornerstone of management by doing pericardiectomy.

Aim of the Study:

This study aimed to review the surgical management of constrictive pericarditis and its surgical outcome.

Materials and Methods:

A retrospective study involved 13 patients with constrictive pericarditis in the Iraqi-cardiac surgery center in Iraqi-Cardiac Surgery Center in Baghdad Medical Complex and Ibn Al-Bitar center for cardiac surgery from 2011 to 2015. Eight (61.5%) of them were female, and the rest (38.5%) were male. Their ages ranged between 10 and 32 years old (the mean age was 21 years). The data were collected from the medical records of the patients.

Results:

The majority of patients were in the age group of 20–29 years (46.1%). The youngest was 10 years old. Dyspnea on exertion was the most presenting feature (61.5%). In the electrocardiogram, atrial fibrillation was found in three patients (23.2%), and a chest X-ray showed calcium deposition at the pericardium in eight patients (61.5%). Cardiac catheterization (right-sided) and transthoracic echo study also demonstrated the findings of the disease. None of the patients needed the by-pass machine. The biopsy results revealed that tuberculosis (TB) was the most frequent cause of pericarditis.

Conclusion:

Pericardiectomy is a useful surgical procedure to treat constructive pericarditis, and it was beneficial to all patients in this study, with improvement in their functional capacity. Another finding of significance is that despite intensive vaccination and the use of anti-TB drugs in our country, TB is still an important cause of constrictive pericarditis.
COVID-19 Vaccine Acceptance among Pregnant Women Attending Antenatal Clinic in a Tertiary Care Hospital of India
Authors: Samanta Sampriti , Bandyopadhyay Alapan , Bhattacherjee Sharmistha , Dasgupta Pallabi
Published: August 2023

Background:

Despite opinions regarding safety and efficacy of COVID-19 vaccines in pregnancy, they are approved for pregnant women. However, little is known about attitudes and perception of pregnant women toward COVID-19 vaccination.

Objective:

To find out COVID-19 vaccine acceptance, its predictors, and perceptions, among pregnant women attending antenatal clinic in a tertiary care hospital of India.

Methodology:

A descriptive cross-sectional study was conducted among 180 pregnant women during 2021 using a predesigned, pretested questionnaire consisting of vaccination, obstetric history, and perception about COVID-19 vaccination. Those who took at least one dose of vaccine was considered vaccine acceptor. Chi-square test was performed to check association with independent variables for vaccine-acceptors and nonacceptors.

Results:

About 126 (70%) women were vaccine-acceptors and 54 (30%) were nonacceptors. Higher proportion of vaccine-acceptors were noted among those aged >20 years (P = 0.003), with previous pregnancy loss (83.3%) and problem in conceiving (71.4%), working mothers (72.7%), lower socioeconomic status (71.1%), and lower literacy (71.2%). Favorable attitudes toward COVID vaccine were present in most of the participants (72.8%). 74.6% of vaccine acceptors and 61.1% nonacceptors agreed to take vaccine on recommendation of health-care provider (P = 0.009). Significantly higher proportion of acceptors (43.7%) agreed to recommend another mother to take vaccine than nonacceptors (24.1%) (P=- 0.044). Significantly higher proportion of acceptors (84.9%) agreed to get vaccinated with precautionary dose if vaccination camp is organized (P = 0.039).

Conclusion:

A high level of vaccine acceptance was seen mostly because of the trust on health-care providers. Targeted efforts are required for health-care workers and public regarding vaccine literacy.
Thyroid Receptor Antibodies and Thyroid Peroxidase Antibodies in a Sample Thyrotoxic Patients: A Cross-Sectional Study
Authors: Mahdi Bahaa Abbas , Ashoor Zainab Fadhel , Salman Issam Noori
Published: August 2023

Background:

Thyrotoxicosis is a clinical status due to hypersecretion of thyroid hormones by diffuse goiter (Grave’s disease [GD]), multinodular goiter, single toxic adenoma, and pituitary adenoma secreting thyroid-stimulating hormone (TSH) rarely. GD: It is diffuse toxic goiter (GD) or (Basedow disease) it is a triad of: Diffuse toxic goiter, hyperthyroidism, and exophthalmos (proptosis).

Aims:

1. Positivity of TRAb and TPO in thyrotoxic subjects. 2. Correlation of the titer of these antibodies with the clinical status of the patients. 3. Correlation between TRAb and TPO titer. 4. To find out if TPO titer on enrollment has any correlation with the clinical status of the patients.

Methods:

A cross-sectional study conducted in the National Diabetes Center–Mustansiriyah University in the period from November 2021 to April 2022 where 93 patients with GD are enrolled to check their thyroid status and check some biochemical variables in their sera as thyrotropin receptor antibody (TRAB), thyroid peroxidase (TPO) antibody, TSH, and free thyroxine (FT4). 44.6% are women and 35.7% are men, at the time of recreuitment 49.4% are toxic while the remaining 58.6% are euthyroid being on anti thyroid drugs. 87 persons are recruited as normal euthyroid, they are sex and age-matched, the control TRAb were negative.

Results:

GD patients are as follows: 54 (58.06%) euthyroid and 39 (41.94%) toxic at the time of recruitment. Eighty-two percent of toxic patients have goiter and 74.07% of euthyroid GD patients have goiter. Ophthalmopathy is found in (64.1% of toxic GD patients and 42.59% of euthyroid GD patients. TPO median in the control, toxic, and euthyroid GD patients is (22.76%), (75%) and (63.5%) (highest among toxic GD patients) (P < 0.001). TSH in the control group has a mean of (2.18 ± 1.72) and a median of (1.89). The TRAb is the highest in toxic GD patients, followed by euthyroid GD patients and the least in the control, its mean is (9.98 ± 8.42), (7.24 ± 7.8) and (0.93 ± 0.15), respectively. It is recommended to conduct a longitudinal study in which patients with GD are checked at variables times in the course of illness (remission and relapse) studying these biochemical and immunological markers in these variable states of thyroid function.

Conclusion:

Ninety-three thyrotoxic patients, 39 are toxic and 54 are euthyroid on arrival. Eye sings are more in toxic patients, goiter and eye signs are predictor of GD, TRAb is the highest among toxic patients, TPO are higher among GD patients versus the control.
Effect of Toxoplasma gondii on the Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 in Women with Toxoplasmosis
Authors: Sultan Sura Abbas , Al-Kuraishi Azhar Hatif , Mahdi Ali Abdul Hussein
Published: August 2023

Background:

Toxoplasmosis is a disease caused by an obligatory intracellular protozoan parasite (Toxoplasma gondii). Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a protein receptor that acts as an immunological checkpoint and reduces immune responses.

Aims:

The present study aimed to evaluate the expression of CTLA-4 protein in women with different toxoplasmosis stages and observed its role in the occurrence of abortion.

Materials and Methods:

Anti-Toxoplasma immunoglobulin M (IgM) and IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA) test in the sera of 116 patients with toxoplasmosis (46 aborted infected groups, 35 pregnant infected groups, and 35 married infected groups). Furthermore, this test was done for 70 control samples (35 aborted women without toxoplasmosis infection and 35 healthy women). As a final point, all samples were examined to measure the level of CTLA-4 using ELISA kits (MyBioSource. Com., Ltd., USA).

Results:

Results showed that a higher level of CTLA-4 was seen in the aborted women group 34 (73.9%) than in other infected groups, and the highest CTLA-4 levels were seen in IgG positive, 20 (43.47%) of 46 in the same group, than other types of antibodies. Furthermore, the highest concentration (948.2 ± 269.4 ng/ml) was indicated in the same group and type of antibodies, with a cutoff value of 597.0 ng/ml (71.7% sensitivity and 97.1% specificity).

Conclusions:

It can be concluded that the CTLA-4 level can be used as a predicted and supported factor for the occurrence of abortion in women infected with toxoplasmosis, especially in the chronic type of the disease (IgG-positive) with a cutoff value of 597.0 ng/ml with 71.7% sensitivity and 97.1% specificity.
Effect of Celecoxib Alone or in Combination of Sitagliptin in Monoiodoacetate Rat Model of Osteoarthritis
Authors: Al-Uqabi Rabab Utba , Al-Gareeb Ali I. , Al-Buhadily Ali K.
Published: August 2023

Background:

Osteoarthritis (OA) is considered an attractive research issue; as it is the most common musculoskeletal progressive condition with no cure yet.

Aims:

To evaluate effect of celecoxib alone or in combination of sitagliptin in monoiodo acetate rat model of OA.

Methods:

A total of 40 Sprague-Dawley male rats were divided into 4 groups, negative control (n=10), positive control group (OA induced by monoiodoacetate (MIA)) (n=10), celecoxib 50mg/kg (n=10), and celecoxib 50mg/kg plus sitagliptin 20mg/kg group (n=10). Serum levels of inflammatory biomarkers and serum CTX-II were assessed for all groups. Data were analyzed statistically by SPSS version 28.00.

Results:

group treated with celecoxib showed a significant reduction in the inflammatory biomarkers and CTX-II serum levels compared with the OA group (P<0.01). A significant reduction in CTX-II level in combination treated group relative to celecoxib treated group.

Conclusion:

Celecoxib imparted anti-inflammatory and cartilage protective effect in OA induced rat model. Sitagliptin combination with celecoxib added an extra cartilage protective effect by reducing cartilage degradation evident by lowering CTX-II serum levels.
Dimensions of the Sphenoid and Ethmoid Sinuses on Computed Tomography: Clinical Implications and Role in Sex Determination
Authors: Ominde Beryl Shitandi , Ikubor Joyce Ekeme , Iju Wilson Josiah , Igbigbi Patrick Sunday
Published: August 2023

Background:

The measurements of the sphenoid and ethmoid sinuses (ESs) are essential in forensic investigations and during endoscopic sinus and skull base surgeries. This study aimed at assessing the dimensions of these sinuses and elucidating their role in sex determination.

Materials and Methods:

This retrospective assessment was conducted using brain-computed tomographic images stored in the Department of Radiology in a Tertiary hospital in Delta State, Nigeria. After institutional ethical approval, images of 292 patients (115 females and 177 males) aged >20 years, were used to measure the dimensions of the ethmoid and sphenoid sinuses (SSs) bilaterally. These were analyzed and summarized using descriptive statistics. Their association with gender, side, or age was assessed using inferential statistics and considered statistically significant at P < 0.05. Discriminant function analysis of the sinus measurements was conducted to evaluate their accuracy in correct sex prediction.

Results:

Both sphenoid and ESs showed significant sexual dimorphism. The ESs showed significant asymmetry (P < 0.05). The anterior width of the left ES (79.8%) was the best sex-discriminating variable. The combination of the left sinus dimensions was more accurate (74.3%, 85.3%) than the right sinuses (72.6%, 81.2%) in sex allocation. Using the bilateral ES dimensions yielded a higher accuracy (89.0%) than using bilateral SS parameters (80.1%).

Conclusion:

The sphenoid and ESs may be used in predicting the sex of an unknown skull bone recovered within the studied population with acceptable accuracy levels.
Killing Efficiency and Full Genome Sequencing of Bacteriophage BAG1 Targeting Endodontic Clinical Strain of Enterococcus faecalis
Authors: Almelan Maha F. , Abbas Uroba Khalid , Al-Zubidi M.
Published: August 2023

Objectives:

Bacterial biofilms can increase the survival of bacteria through providing resistance to conventional disinfectants as well as antibiotics, thus biofilm considered a serious risk to human health with hug loss. Consequently, novel approaches to deal with bacterial biofilms are required. Viruses that may eradicate bacteria are known as bacteriophages, they are also known as “bacteria eaters.” Due to their activity on bacteria, bacteriophages are distinct from other organisms and do not pose a threat to human. Consequently, they are regarded as secure substitutes for antibiotics in the management of bacterial infections.

Aim of the Study:

In this study, we report the full genome sequencing of bacteriophage, namely BAG1 that targeting an endodontic clinical strain of Enterococcus faecalis (K3). Furthermore, we evaluate it killing efficiency to eliminate E. faecalis in both planktonic media and dentine slabs.

Materials and Methods:

We used the previously isolated endodontic E. faecalis clinical strain, namely K3 and enterococcus bacteriophage BAG1 in this study by spotting on the double layer agar technique. DNA extracted proceeded with NORGEN phage DNA isolation kit. Phage full genome sequencing was performed using Illumina nova Seq 600, 150 bp PE. In addition, the killing capacity of BAG1 phage against E. faecalis K3 was measured by infecting 5 × 106
E. faecalis with BAG1 phage at multiplicity of infection of 0.1. Furthermore, the biofilm fraction and the number of E. faecalis colony-forming unit in planktonic media were measured after infecting 24 dentine slabs with K3 bacteria and BAG1 phage. SYTO® 9 green LIVE/DEAD® BacLight Bacterial Viability Kits were used to visualize K3 biofilm on dentine slabs using fluorescent microscope.

Results:

Full Genome Organization of BAG1 phage was circular composed of 68 open reading frame with GC percentage of 34.56%. An efficient killer reflecting by completely eliminating K3 strain within 180 min in killing test. In addition, the result revealed that BAG1 highly significant to eliminate K3 bacteria in both planktonic broth and biofilm fraction obtained from dentine slabs infection with the endodontic K3 clinical strain.

Conclusion:

Our results support that anti E. faecalis bacteriophage BAG1 significantly eliminate biofilm of E. faecalis K3 on dentine slabs with a lytic properties due to the absence of lysogenic genes which make it a suitable substitute to adjunctive anti E. faecalis therapy.
Mutation Status Defines Subtypes of Essential Thrombocythemia and Relation to Polycythemia Vera in Iraqi Patients
Authors: Al Dayyeni Aseel Modhfer , Al-Gailani Bassam T. , Mahdi Mohammed Ghanim
Published: August 2023

Background:

Polycythemia vera (PV) and essential thrombocythemia (ET) are a part of the BCR-ABL1-negative myeloproliferative neoplasms (MPNs) that harbor mutation in Janus kinase 2 (JAK2), CALR, or MPL gene.

Objectives:

The objective of this study was to investigate the impact of JAK2 and CALR mutations on the clinical course and hematological phenotype of ET patients and to evaluate the biological and clinical features of ET and PV sharing the same type of mutation in JAK2V617F.

Materials and Methods:

This was a cross-sectional study that included 94 patients diagnosed with MPN, of them 47 had PV and 47 had ET. JAK2V617F mutation was assessed using either allele-specific PCR or JAK-2 quantitative real-time PCR kit. JAK2-negative patients were further assessed for the existence of CALR mutations using SNP biotechnology MPN screening kit.

Results:

JAK2 mutation was identified in 29 ET patients, whereas CALR mutations were confirmed in 18 patients. JAK2-mutated ET patients were significantly older than those with CALR mutations. Seventy-six were reported to have a mutation in JAKV617F, of them 47 were diagnosed as PV and 29 as ET. JAK2V617F-mutated PV patients had significantly higher levels of hemoglobin, hematocrit, and WBC than JAK2-mutated ET patients. On the other hand, JAK2-mutated PV patients exhibited lower platelet count than ET harboring the same mutation.

Conclusion:

JAK2-mutated ET represents a distinct clinical entity that has a hematological and clinical phenotype ranging between JAK2-mutated PV and CALR-mutated ET. The analysis of the mutational status is essential in discriminating subtypes of MPN and confirming the diagnosis in ET and PV patients.
Absolute continuity in families of parametrised non-homogeneous self-similar measures
Authors: Käenmäki Antti , Orponen Tuomas
Published: August 2023

Let

\mu

be a planar self-similar measure with similarity dimension exceeding

1

, satisfying a mild separation condition, and such that the fixed points of the associated similitudes do not share a common line. Then, we prove that the orthogonal projections

\pi_{e\sharp}(\mu)

are absolutely continuous for all

e \in S^{1} \setminus E

, where the exceptional set

E

has zero Hausdorff dimension. The result is obtained from a more general framework which applies to certain parametrised families of self-similar measures on the real line. Our results extend the previous work of Shmerkin and Solomyak from 2016, where it was assumed that the similitudes associated with

\mu

have a common contraction ratio.
Tarefas Matemáticas na Formação de Professores que Ensinam Matemática
Authors: Cyrino Márcia Cristina Costa Trindade , Estevam Everton José Goldoni
Published: August 2023

Com base em um movimento diacrônico de pesquisas e de experiências formativas, este artigo apresenta um texto de natureza reflexiva e interpretativa sobre ações de formação e indícios decorrentes delas que permitem compreender o papel do trabalho com tarefas matemáticas na/para a formação de Professores que Ensinam Matemática (PEM). Nesse movimento, são sublinhadas três ações em contextos formativos de PEM, alicerçadas no trabalho com tarefas matemáticas: resolução e análise de tarefas matemáticas; seleção, adequação, elaboração e exploração de tarefas matemáticas; e reflexões e discussões a respeito do trabalho com tarefas na sala de aula. Os elementos que circunstanciam essas ações evidenciam um quadro denso e articulado que aponta o potencial do trabalho com tarefas matemáticas para a aprendizagem profissional de PEM. O quadro problematizado pode orientar o planejamento, a implementação e avaliações de programas e ações de formação de PEM alicerçados no trabalho com tarefas matemáticas, tanto no campo da pesquisa quanto da prática.
Task Design for Klein’s Second Discontinuity
Authors: Winsløw Carl , Huo Rongrong
Published: August 2023

Since the 19th century, studies of mathematics at university have been a main component of the usual preparation for teaching at secondary level. Already around 1900, Klein pointed out that specific measures are needed to ensure that the university mathematical preparation becomes useful to the teacher, and he insisted that universities themselves must take responsibility for these measures. In this paper, we discuss this problem, as it presents itself in 2022, and we present and exemplify some principles of task design which are intended to support students’ mobilisation of university mathematical knowledge in relation to specific mathematical challenges for high school teachers.
Potencialidades e desafios de tarefas de aprendizagem de matemática no desenvolvimento de THA
Authors: Oliveira Lucas Rosa Sá , Traldi Junior Armando
Published: August 2023

Neste artigo apresenta-se a síntese do resultado de uma pesquisa qualitativa do tipo pesquisa-ação, sobre o ensino-aprendizagem dos números racionais em tarefas de matemática desenvolvidas por grupos de estudantes do Ensino Médio. Foi realizado um estudo bibliográfico no portal de dissertações e teses da Capes com o intuito de verificar os tipos de tarefas utilizadas em pesquisas recentes. Após essa análise, adotou-se como pressupostos teóricos: a Trajetória Hipotética de Aprendizagem (THA) para elaborar as tarefas de matemática e entender os caminhos percorridos pelos estudantes; as representações e os significados dos números racionais para construir as tarefas de matemática e a Teoria APOS para analisar os dados encontrados. Os resultados esperados foram ao encontro dos objetivos e das hipóteses da THA, além de possibilitar a identificação das potencialidades e desafios das tarefas de números racionais no Ensino Médio.