bluuebunny/crossref_metadata_2025 huggingface dataset:
A Política De Qualificação Docente Da Universidade Do Estado Do Amazonas: Sua Inserção Nos Projetos De Pesquisa, Desenvolvimento E Inovação E O Desenvolvimento Local
Authors: Araujo Marcus Orleans Arnaud , Araújo Paulo César Diniz De , Almeida Fernanda Maria De , Maduro Márcia Ribeiro , Filho Wlademir Leite Correia
Published: January 2025

O objetivo geral deste estudo foi analisar a relação da política de qualificação docente da Universidade do
Estado do Amazonas, sua inserção nos projetos de Pesquisa, Desenvolvimento e Inovação (PD&I) vinculados ao
PIM e o desenvolvimento local. Especificamente, buscou-se: (a) descrever os processos e a política de
qualificação docente da UEA; (b) analisar e descrever a inserção da UEA nos projetos PD&I vinculados ao PIM
e o quanto a qualificação docente está relacionada com tal inserção; e, (c) identificar a relação entre a
qualificação docente e o desenvolvimento local. A análise teve como referência os docentes que tiveram vínculo
com a UEA, no período entre 2002 e setembro de 2022. Para o atendimento dos objetivos (a) e (b), utilizou-se de
análises documentais. Para avaliar as relações propostas, empregou-se o Teste de Correlação de Pearson.
Quanto aos resultados da pesquisa, o processo de qualificação docente entre 2014 e 2022 propiciou elevado
percentual de titulados (53% doutores e 39% mestres). A captação de recursos por meio de projetos de PD&I
atingiu valores relevantes e consolidados desde o ano de 2019, que captou o valor recorde de R$ 81.397.179,99.
Os testes de correlação de Pearson apontaram forte associação entre a qualificação docente e os indicadores de
desenvolvimento regional. Assim, pode-se concluir que a qualificação docente é fator essencial para impulsionar
o desenvolvimento local. Estes resultados confirmam o papel da Universidade do Estado do Amazonas no
processo de desenvolvimento regional, sobretudo no sentido de favorecer o desenvolvimento econômico no interior do estado do Amazonas.
A Política de Qualificação Docente da Universidade do Estado do Amazonas e a sua Produção Científica
Authors: Araujo Marcus Orleans Arnaud , Araújo Paulo César Diniz de , Almeida Fernanda Maria de , Maduro Márcia Ribeiro , Filho Wlademir Leite Correia
Published: January 2025

O objetivo geral deste estudo foi analisar como a produção científica da UEA é afetada pela política de
qualificação da Universidade. Especificamente, buscou-se: (a) descrever os processos e a política de
qualificação docente da UEA e (b) identificar a evolução da produção científica dos docentes da UEA e o
quanto a qualificação docente está relacionada com tal evolução. A análise teve como referência a evolução
da titulação dos docentes até o mês de setembro de 2022 e da produção científica da UEA no período entre
2014 e setembro de 2021. Para o atendimento dos objetivos utilizou-se de análise documental e para avaliar a
relação empregou-se o Teste de Correlação de Pearson. Quanto aos resultados da pesquisa, o processo de
qualificação docente propiciou elevado percentual de titulados (53% doutores e 39% mestres). A produção
científica obteve significativo incremento, com aumento de 119,30% entre os anos de 2014 e 2020. Os testes de
correlação de Pearson apontaram forte associação entre a qualificação docente e o indicador de produção científica. Assim, pode-se concluir que a qualificação docente é fator essencial para o aumento da produção científica.
Green Hydrogen And Education: Ceará's Role In The Brazilian Energy Transition
Authors: Silva Cleilson Coutinho Da , Neto Alcides Feitosa , Gomes Rickardo Léo Ramos
Published: January 2025

Background: The Brazilian Basic Education system, particularly in the state of Ceará, is pivotal in preparing
students to face the challenges and opportunities of a low-carbon economy, especially with the integration of
green hydrogen production. By incorporating study subjects focused on sustainability, renewable energy, and
technological innovation into the school curriculum, Basic Education promotes the development of critical and
scientific thinking from an early age. This knowledge is essential for professional training, enabling the
implementation of clean technologies, such as green hydrogen production, using Ceará's abundant wind and solar
energy resources.
Materials and Methods: The research adopted a qualitative approach, utilizing two methodological procedures:
(1) bibliographic research for theoretical grounding and analysis of essential concepts, and (2) documentary
research focusing on institutional and regulatory sources supporting discussions on Ceará's initiatives within the
energy transition context.
Results: The study identified that initiatives like H-TEC and educational practices in Natural Sciences and
Mathematics significantly contribute to Ceará's role in the Brazilian energy transition. These initiatives
emphasize the importance of fostering knowledge and technology areas to enhance education and prepare
students for active roles in the renewable energy sector.
Conclusion: Strengthening education in sustainability, renewable energy, and technological innovation equips
students to contribute to the global energy transition. This effort supports the development of an economically sustainable, greener, and more prosperous future, aligning with the goals of the Brazilian energy transition
Implementing Excellence In After Sales: Strategies And Best Practices
Authors: Sousa Elisângela Alves De , Machado Herus Orsano , Ferreira Antonio Vinicius Oliveira Ferreira , Araújo Anderson Lopes De , Feitosa Aryadynna Santos
Published: January 2025

Background: The contemporary scenario of high competitiveness requires companies to have robust strategies
to win and keep consumers. After-sales emerges as an essential pillar to guarantee loyalty, going beyond simple
customer satisfaction. This article explores the implementation of after-sales excellence, highlighting strategies
and practices that strengthen the company-consumer relationship in a "one-to-one" model.
Historical analysis reveals how technological advances and the evolution of marketing have shaped the industry.
From the mass production model of Taylor and Ford, to Japan's flexible, technological approach of the 1970s, a
focus on efficiency and meeting consumer demands has become central. The introduction of marketing in the
1950s marked a new era, using tools and advertising campaigns to understand and capture the customer's spirit,
ensuring loyalty and building value.
From the 1980s onwards, marketing redirected efforts towards after-sales, prioritizing a personalized and lasting
relationship. Innovative strategies, such as the intensive use of technology and the creation of direct
communication channels, have consolidated after-sales as an essential tool for differentiating brands in saturated
markets. This study also addresses the importance of integration between sectors, such as sales and after-sales,
to avoid failures in the consumption cycle.
Conclusion: History demonstrates the relevance of integrated communication between production, sales and
consumption for building solid relationships with customers. This article analyzes the evolution of after-sales as
a strategic tool, linked to marketing and technological advances, highlighting the importance of balancing
innovation and personalization.
After-sales, strengthened by investments in information and communication technologies, such as Big Data,
becomes essential to understand and meet consumer demands. However, relying exclusively on technological solutions neglects the human element, which is essential in building lasting connections.
Estratégias E Desafios Para A Transformação Digital Nas Instituições De Ensino Superior Do Norte Do Brasil
Authors: Nascimento Antonio Carlos Rabelo , Ferko Geórgia Patrícia Da Silva , Souza Lena Simone Barata , Lopes Isaque Samuel Silva Fragoso
Published: January 2025

Este trabalho buscou investigar como 9 Instituições de Ensino Superior (IES) públicas do Norte do Brasil estão
lidando com a transformação digital. A pesquisa utiliza-se de uma abordagem qualitativa e descritiva, com
análise de dados dos relatórios de gestão de 2023 de cada uma delas. Foram exploradas ações relacionadas a
investimentos em TIC e infraestrutura, governança e gestão de TIC, capacitação e uso de tecnologias digitais,
inovação tecnológica e inclusão digital e desafios e planos futuros. A análise revelou avanços significativos, como
o fortalecimento de conectividade, adoção de ferramentas digitais, criação de planos diretores de TIC e
desenvolvimento de projetos inovadores. Algumas dessas instituições destacaram-se por iniciativas inclusivas,
como a capacitação de populações vulneráveis e a criação de incubadoras tecnológicas. Contudo, vários desafios
persistem, incluindo a insuficiência de investimentos, a precariedade em áreas remotas e a necessidade de
integração mais efetiva entre tecnologia e práticas pedagógicas. Os resultados indicam que, embora avanços
tenham sido alcançados, a transformação digital nessas instituições demanda esforços contínuos e estratégias
colaborativas. Em suma, investimentos em infraestrutura, políticas inclusivas e compartilhamento de boas práticas são fundamentais para superar desigualdades e alinhar as IES do Norte às exigências da transformaçãodigital.
Perception and Awareness of Diabetes Risk and Reported Risk-Reducing Behaviors in Adolescents
Authors: Chu Patricia , Patel Arya , Helgeson Vicki , Goldschmidt Andrea B. , Ray Mary Katherine , Vajravelu Mary Ellen
Published: May 2023

Importance

Lifestyle change is central to diabetes risk reduction in youth with overweight or obesity. Feeling susceptible to a health threat can be motivational in adults.

Objective

To evaluate associations between diabetes risk perception and/or awareness and health behaviors in youth.

Design, Setting, and Participants

This cross-sectional study analyzed data from the US National Health and Nutrition Examination Survey 2011 to 2018. Participants included youths aged 12 to 17 years with body mass index (BMI) in the 85th percentile or higher without known diabetes. Analyses were conducted from February 2022 to February 2023.

Main Outcomes and Measures

Outcomes included physical activity, screen time, and attempted weight loss. Confounders included age, sex, race and ethnicity, and objective diabetes risk (BMI, hemoglobin A1c [HbA1c]).

Exposures

Independent variables included diabetes risk perception (feeling at risk) and awareness (told by clinician), as well as potential barriers (eg, food insecurity, household size, insurance).

Results

The sample included 1341 individuals representing 8 716 794 US youths aged 12 to 17 years with BMI in the 85th percentile or higher for age and sex. The mean age was 15.0 years (95% CI, 14.9-15.2 years) and mean BMI z score was 1.76 (95% CI 1.73-1.79). Elevated HbA1c was present in 8.6% (HbA1c 5.7%-6.4%: 8.3% [95% CI, 6.5%-10.5%]; HbA1c ≥6.5%: 0.3% [95% CI, 0.1%-0.7%]). Nearly one-third of youth with elevated HbA1c reported risk perception (30.1% [95% CI, 23.1%-38.1%), while one-quarter (26.5% [95% CI, 20.0%-34.2%]) had risk awareness. Risk perception was associated with increased TV watching (β = 0.3 hours per day [95% CI, 0.2-0.5 hours per day]) and approximately 1 less day per week with at least 60 minutes of physical activity (β = −1.2 [95% CI, −2.0 to −0.4) but not with nutrition or weight loss attempts. Awareness was not associated with health behaviors. Potential barriers had mixed associations: larger households (≥5 members vs 1-2) reported lower consumption of non–home-prepared meals (OR 0.4 [95% CI, 0.2-0.7]) and lower screen time (β = −1.1 hours per day [95% CI, −2.0 to −0.3 hours per day), while public insurance (vs private) was associated with approximately 20 fewer minutes per day of physical activity (β = −20.7 minutes per day [95% CI, 35.5 to −5.8 minutes per day]).

Conclusions and Relevance

In this cross-sectional study including a US-representative sample of adolescents with overweight or obesity, diabetes risk perception and awareness were not associated with greater engagement in risk-reducing behaviors in youth. These findings suggest the need to address barriers to engagement in lifestyle change, including economic disadvantage.
Mammary adipocyte flow cytometry as a tool to study mammary gland biology
Authors: Hanin Geula , Ferguson‐Smith Anne C.
Published: May 2023

The mammary gland is a vital exocrine organ that has evolved in mammals to secrete milk and provide nutrition to ensure the growth and survival of the neonate The mouse mammary gland displays extraordinary plasticity each time the female undergoes pregnancy and lactation, including a sophisticated process of tertiary branching and alveologenesis to form a branched epithelial tree and subsequently milk‐producing alveoli. Upon the cessation of lactation, the gland remodels back to a simple ductal architecture via highly regulated involution processes. At the cellular level, the plasticity is characterised by proliferation of mammary cell populations, differentiation and apoptosis, accompanied by major changes in cell function and morphology. The mammary epithelium requires a specific stromal environment to grow, known as the mammary fat pad. Mammary adipocytes are one of the most prominent cell types in the fat pad, but despite their vast proportion in the tissue and their crucial interaction with epithelial cells, their physiology remains largely unknown. Over the past decade, the need to understand the properties and contribution of mammary adipocytes has become more recognised. However, the development of adequate methods and protocols to study this cellular niche is still lagging, partially due to their fragile nature, the difficulty of isolating them, the lack of reliable cell surface markers and the heterogenous environment in this tissue, which differs from other adipocyte depots. Here, we describe a new rapid and simple flow cytometry protocol specifically designed for the analysis and isolation of mouse mammary adipocytes across mammary gland developmental stages.
Estimating size specific dose estimate from computed tomography radiograph localizer with radiation risk assessment
Authors: Burton Christiane Sarah , Al‐Ward Shahad
Published: May 2023

Background

Quantifying radiation burden is necessary for optimizing imaging protocols. The normalized dose coefficient (NDC) is determined from the water‐equivalent diameter (WED) and is used to scale the CTDIvol based on body habitus to determine the size specific dose estimate (SSDE). In this study we determine the SSDE prior to the CT scan and how sensitive the SSDE from WED is to the lifetime attributable risk (LAR) from BEIR VII.

Method

For calibration, phantom images are used to relate the mean pixel values along a profile () of the CT localizer to the water‐equivalent area (AW) of the CT axial scan at the same z‐location. Images of the CTDIvol phantoms (32 cm, 16 cm, and ∼1 cm) and ACR phantom (Gammex 464) were acquired on four scanners. The relationship between the AW and was used to calculate the WED from the CT localizer for patient scans. A total of 790 CT examinations of the chest and abdominopelvic regions were used in this study. The effective diameter (ED) was calculated from the CT localizer. The LAR was calculated based on the patient chest and abdomen using the National Cancer Institute Dosimetry System for Computed Tomography (NCICT). The radiation sensitivity index (RSI) and risk differentiability index (RDI) were calculated for SSDE and CTDIvol.

Results

The WED from CT localizers and CT axials scans show good correlation (R2 = 0.96) with the maximum percentage difference being 13.45%. The NDC from WED correlates poorly with LAR for lungs (R2 = 0.18) and stomach (R2 = 0.19), however that is the best correlation.

Conclusion

The SSDE can be determined within 20% as recommended by the report of AAPM TG 220. The CTDIvol and SSDE are not good surrogates for radiation risk, however the sensitivity for SSDE improves when using WED instead of ED.
Which phish is captured in the net? Understanding phishing susceptibility and individual differences
Authors: Sarno Dawn M. , Harris Maggie W. , Black Jeffrey
Published: May 2023

Phishing research presents conflicting findings regarding the psychological predictors of phishing susceptibility. The present work aimed to resolve these discrepancies by utilizing a diverse online sample and email set. Participants completed a survey that included an email classification task and measured several individual differences, including phishing awareness, age, impulsivity, curiosity, and personality (the Big‐5). Phishing susceptibility was measured by participants' ability to distinguish between phishing and legitimate emails. Three regression analyses were performed to predict email discrimination ability; (1) an age model, (2) a deficient self‐regulation model (i.e., impulsivity, response times, and curiosity), and (3) a personality (i.e., the Big‐5) model. Overall, phishing susceptibility was predicted by younger age, higher levels of impulsivity and extraversion, lower levels of openness to experience and agreeableness, and quick responses. The present work identifies several populations that are particularly vulnerable to phishing attacks and may require targeted training interventions.
Data filtering based multi‐innovation gradient identification for bilinear systems with colored noise
Authors: Wu Xiaoqiang
Published: May 2023

System identification is the powerful tool to establish the mathematical models of practical systems. This article considers the parameter identification for bilinear systems with colored noise. First, the bilinear system is transformed into an input‐output form by eliminating the state variables in the model. Then, based on the data filtering technique, the measured input‐output data is filtered using an estimated noise transfer function, and a filtering based generalized extended stochastic gradient (F‐GESG) algorithm is proposed to enhance the parameter estimation accuracy. Furthermore, the multi‐innovation identification theory is employed to improve the convergence speed of the proposed F‐GESG algorithm, and a filtering based multi‐innovation generalized extended stochastic gradient (F‐MI‐GESG) algorithm is developed to identify the parameters of bilinear systems. The GESG algorithm is given for comparison. Finally, a numerical simulation example is provided to illustrate the effectiveness and excellent performance of the proposed algorithms.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer
Authors: Ruan Zhihui , Chi Jiangyang , Kong Yue , Li Chengcheng , Ruan Xiaolan , Zhou Xing , Chen Yanxi , Li Yongkui , Luo Zhen
Published: May 2023

Colorectal cancer (CRC) is an intestinal malignant tumor with high morbidity and mortality worldwide. Inoperability or resistanance to radiation and chemotherapy occur in the conventional treatments against CRC. Oncolytic viruses (OVs) are one kind of virus that selectively infects and lyses cancer cells, which is considered to be a new anticancer therapy with biological and immune‐based approaches. Enterovirus 71 (EV71), belonging to the enterovirus genus in the family Picornaviridae, is a single positive‐stranded RNA virus. EV71 is transmitted in a fetal‐oral route and infects gastrointestinal tract in infants. Here, EV71 is exploited to be a novel oncolytic virus in colorectal cancer. It is revealed that EV71 infection can selectively cause colorectal cancer cells cytotoxicity but not primary intestinal epithelial cells. Consistently, EV71 injection significantly inhibits tumor growth in nude mice xenografted colorectal cancer cells. In detail, EV71 infects colorectal cancer cells to repress the expression of Ki67 and B‐cell leukemia 2 (Bcl‐2) leading to the inhibition of cell proliferation, while activating the cleavage of poly‐adenosine diphosphatase‐ribose polymerase and Caspase‐3 protein resulting in the promotion of cell apoptosis. The findings demonstrate the oncolytic feature of EV71 in CRC treatment and may provide a potential clue for clinical anticancer therapy.
Extrusion‐Based 3D Bioprinting of Adhesive Tissue Engineering Scaffolds Using Hybrid Functionalized Hydrogel Bioinks
Authors: Chen Shuai , Tomov Martin L. , Ning Liqun , Gil Carmen J. , Hwang Boeun , Bauser‐Heaton Holly , Chen Haifeng , Serpooshan Vahid
Published: May 2023

Adhesive tissue engineering scaffolds (ATESs) have emerged as an innovative alternative means, replacing sutures and bioglues, to secure the implants onto target tissues. Relying on their intrinsic tissue adhesion characteristics, ATES systems enable minimally invasive delivery of various scaffolds. This study investigates development of the first class of 3D bioprinted ATES constructs using functionalized hydrogel bioinks. Two ATES delivery strategies, in situ printing onto the adherend versus printing and then transferring to the target surface, are tested using two bioprinting methods, embedded versus air printing. Dopamine‐modified methacrylated hyaluronic acid (HAMA‐Dopa) and gelatin methacrylate (GelMA) are used as the main bioink components, enabling fabrication of scaffolds with enhanced adhesion and crosslinking properties. Results demonstrate that dopamine modification improved adhesive properties of the HAMA‐Dopa/GelMA constructs under various loading conditions, while maintaining their structural fidelity, stability, mechanical properties, and biocompatibility. While directly printing onto the adherend yields superior adhesive strength, embedded printing followed by transfer to the target tissue demonstrates greater potential for translational applications. Together, these results demonstrate the potential of bioprinted ATESs as off‐the‐shelf medical devices for diverse biomedical applications.
Facile Synthesis of Highly Stretchable, Tough, and Photodegradable Hydrogels
Authors: Fonseca Rita G. , Kuster Aline , Fernandes Pedro P. , Tavakoli Mahmoud , Pereira Patrícia , Fernandes José R. , De Bon Francesco , Serra Arménio C. , Fonseca Ana C. , Coelho Jorge F. J.
Published: May 2023

Recently, highly stretchable and tough hydrogels that are photodegradable on‐demand have been reported. Unfortunately, the preparation procedure is complex due to the hydrophobic nature of the photocrosslinkers. Herein, a simple method is reported to prepare photodegradable double‐network (DN) hydrogels that exhibit high stretchability, toughness, and biocompatibility. Hydrophilic ortho‐nitrobenzyl (ONB) crosslinkers incorporating different poly(ethylene glycol) (PEG) backbones (600, 1000, and 2000 g mol−1) are synthesized. These photodegradable DN hydrogels are prepared by the irreversible crosslinking of chains by using such ONB crosslinkers, and the reversible ionic crosslinking between sodium alginate and divalent cations (Ca2+). Remarkable mechanical properties are obtained by combining ionic and covalent crosslinking and their synergistic effect, and by reducing the length of the PEG backbone. The rapid on‐demand degradation of these hydrogels is also demonstrated by using cytocompatible light wavelength (λ = 365 nm) that degrades the photosensitive ONB units. The authors have successfully used these hydrogels as skin‐worn sensors for monitoring human respiration and physical activities. A combination of excellent mechanical properties, facile fabrication, and on‐demand degradation holds promise for their application as the next generation of substrates or active sensors eco‐friendly for bioelectronics, biosensors, wearable computing, and stretchable electronics.
Millimeter‐Thick Liquid Crystalline Elastomer Actuators Prepared by‐Surface‐Enforced Alignment
Authors: McCracken Joselle M. , Hoang Jonathan D. , Herman Jeremy A. , Lynch Kelsey M. , White Timothy J.
Published: May 2023

Liquid crystalline elastomers (LCE) are thermally cyclable, compliant actuators with compelling mechanical properties. The large and programmable deformation of LCE has led to numerous functional examinations spanning optics, medical devices, and robotics. A well‐established method to prepare complex LCE actuators is to utilize surface‐enforced photoalignment. Herein, a facile and scalable approach is reported to circumvent the physical limits of surface‐enforced alignment (e.g., samples that are 50 µm or less) to amplify the achievable force output in LCE. Applying an approach termed direct layering, the thermomechanical response of LCE elements prepared with +1 disclination patterns in a range of compositions and thicknesses is contrasted. The design and preparation of +1 disclination patterns and arrays is explored to assess the contribution of sample geometry and overlap to deformation and force output. The methodology detailed in this contribution allows for the preparation of elements ≈1 mm in thickness that are capable of actuating large objects. Furthermore, the fabrication of these elements uniquely enables the realization of mechanical instabilities to hasten the actuation rate in response to thermal change and to enable leaping.
Emergence and Relaxation of an e–h Quantum Liquid Phase in Photoexcited MoS2 Nanoparticles at Room Temperature
Authors: Dey Pritha , Dixit Tejendra , Mishra Vikash , Sahoo Anubhab , Vijayan Cheriyanath , Krishnan Sivarama
Published: May 2023

Low‐dimensional transition metal dichalcogenide (TMDC) materials are heralding a new era in optoelectronics and valleytronics owing to their unique properties. Photo‐induced dynamics in these systems is mostly studied from the perspective of individual quasi‐particles—excitons, bi‐excitons, or, even, trions—their formation, evolution, and decay. The role of multi‐body and exciton dynamics, the associated collective behavior, condensation, and inter‐excitonic interactions remain intriguing and seek attention, especially in room‐temperature scenarios that are relevant for device applications. In this work, the formation and decay of an unexpected electron–hole quantum liquid phase at room‐temperature on ultrafast timescales in multi‐layer MoS2 nanoparticles is evidenced through femtosecond broadband transient absorption spectroscopy. The studies presented here reveal the complete dynamical picture: the initial electron–hole plasma (EHP) condenses into a quantum electron–hole liquid (EHL) phase that typically lasts as long as 10 ps, revealing its robustness, whereafter the system decays through phonons. The authors employ a successful physical model using a set of coupled nonlinear rate equations governing the individual populations of these constituent phases to extract their contributions to bandgap renormalization (BGR). Beyond the observation of the electron–hole liquid‐like state at room temperature, this work reveals the ultrafast dynamics of photo‐excited low‐dimensional systems arising out of collective many‐particle behavior and correlations.
A Highly Sensitive Triboelectric Quasi‐Zero Stiffness Vibration Sensor with Ultrawide Frequency Response
Authors: Wu Pengfan , Wang Fayang , Xu Shiwei , Liu Tao , Qi Youchao , Zhao Xue , Zhang Chi , Mu Xiaojing
Published: May 2023

Sensors based on triboelectric nanogenerators (TENGs) have gained worldwide interest owing to their advantages of low cost and self‐powering. However, the detection of most triboelectric vibration sensors (TVS) is restricted to low frequency, whereas high‐frequency vibration signals are successfully measured in recent studies; their sensitivity still requires improvement. Hence, a highly sensitive vibration sensor based on TENG (HSVS‐TENG) with ultrawide frequency response is presented. This study is the first to introduce a quasi‐zero stiffness structure into the TENG to minimize the driving force by optimizing the magnetic induction intensity and the weight of the moving part. The results show that the HSVS‐TENG can measure vibrations with frequencies ranging from 2.5 to 4000 Hz, with a sensitivity ranging from 0.32 to 134.9 V g−1. Moreover, the sensor exhibits a good linear response versus the applied acceleration, and the linearity ranges from 0.08 to 2.81 V g−1. The self‐powered sensor can monitor the running state and fault type of the key components with a recognition accuracy of 98.9% by leveraging machine‐learning algorithms. The results reach a new height for the ultrawide frequency response and high sensitivity of the TVS and provide an idea for a follow‐up high‐resolution TVS.
Enhanced Stretchability of Wavy‐Structured Thermally Grown Silicon Dioxide Films for Stretchable Encapsulation
Authors: Kim Hangeul , Hwang Gyeong‐Seok , Lee Sukbin , Kim Ju‐Young
Published: May 2023

Aligned wavy‐structured thermally grown silicon dioxide films are fabricated for stretchable encapsulation films. Uniaxial stretchability is investigated with micromechanics modeling, which can elucidate the stretchability arising from the wavy structure and the properties of the materials. The wavy‐structured films with optimum combinations of film thickness and wavy structure show 20.1% of uniaxial stretchability and 1.11 × 10−6 g m−2 day−1 of water vapor transmission rate (WVTR), simultaneously. It shows highly reliable barrier properties even after 1000 stretching cycles at 90% of their stretchability.
Response of Camellia sinensis var.assamica suitable areas to climate change—Evidence from Yunnan province (China)
Authors: Yi Qi , Gao Yuting , Dou Xiaodong , Peng Qiyang , Shen Yinghua , Ji Wenjuan , Liu Yujie
Published: May 2023

This study is an attempt to explore the regional resilience of Camellia sinensis var.assamica cultivation with climate change in Yunnan Province and delineate the scope of its potential suitable areas at three levels. Based on the maximum entropy (MaxEnt) model, combined with the distribution data of C. sinensis var.assamica species and environmental variable data, the main influencing factors of its distribution were figured out, and the suitable growing areas of C. sinensis var.assamica under the current and future climate conditions were predicted. The results show (1) the MaxEnt model can be deliberately constructed for the prediction of the suitable distribution areas of C. sinensis var.assamica in Yunnan. The dominant environmental factors affecting the planting of it are the average rainfall in October, the soil type and the mountain slope, having a contribution ratio of 84.9% with a total. (2) Under the current climate condition, the areas suitable for C. sinensis var.assamica are mainly in the west, southwest and south regions of Yunnan. The total suitable areas account for approximately 37.55% of Yunnan. The highly suitable areas are surrounded by moderately suitable areas which are surrounded by low suitable areas. (3) In the scenarios of RCP4.5 and RCP8.5, the total suitable area shows an increasing trend, reaching 41.76% and 52.30% of the land area of Yunnan Province, respectively. With higher carbon emissions, the increase in suitable area will be greater. The centroid of the suitable area would migrate toward higher altitude and higher latitude. The growers can adjust the suitable areas according to the local climate and terrain conditions and the conclusions of this paper to cope with impact of climate change on the yield of C. sinensis var.assamica.
Yield tradeoffs of early corn harvest to enhance pennycress establishment
Authors: Mohammed Yesuf Assen , Gesch Russ W. , Wells Samantha S. , Heller Nicholas J. , Lindsey Alexander J. , Hard Alexander W. , Phippen Winthrop B. , Bedeker Bethany
Published: May 2023

Oilseed pennycress (Thlaspi arvense L.) establishment following grain corn (Zea mays L.) harvest in northern latitudes is challenging because of the short duration between corn harvest and soil freeze. The use of shorter season corn hybrids for a region may partly solve this challenge, but tradeoffs in reduced corn yield may be a concern. This study evaluated corn relative maturity (CRM) hybrids on pennycress establishment, seed and oil yields, and corn grain yield tradeoffs. The CRM hybrids ranged from 76‐ to 95‐day for northern sites (Morris and Rosemount, MN), and from 95‐ to 113‐day for the southern sites (Custar, OH, and Lexington, IL). The checks were full‐season corn (113‐ and 95‐day corn for the southern and the northern sites, respectively) harvested for silage. Pennycress plant density, green cover, and yield were generally greater when pennycress was seeded following silage corn due to early seeding and reduced corn stover. Pennycress seed yields ranged from 388 to 778, 641 to 834, 362 to 784, and 834 to 2038 kg ha−1 at Custar, Lexington, Morris, and Rosemount, respectively. The results showed that growing 86‐ and 105‐day grain corn in the northern and southern sites, respectively, facilitated timely pennycress establishment with little or no corn grain yield loss compared with full‐season hybrids. Developing pennycress varieties better suited for emergence under high corn stover or employing stover management practices to increase autumn emergence is suggested. Additionally, an economic analysis of the entire cropping sequence (corn–pennycress–soybean) is needed.
Inpatient epidemiology, healthcare utilization, and association with comorbidities of Turner syndrome: A National Inpatient Sample study
Authors: Chenbhanich Jirat , Ungprasert Patompong , Kroner Paul T.
Published: May 2023

We aimed to investigate the prevalence, resource utilization, and comorbidities of patients with Turner syndrome (TS) hospitalized in the United States. We identified patients within the Nationwide Inpatient Sample database from the year 2017 to 2019. A propensity‐matched cohort of non‐TS patients from the same database was constructed to serve as comparators. There were 9845 TS patients, corresponding to inpatient prevalence of 10.4 per 100,000 admissions. The most common admission diagnosis was sepsis (27.9%). TS patients had higher inpatient mortality (adjusted odds ratio 2.16, 95% confidence interval 1.57–2.96) and morbidity, including shock, ICU admission, acute kidney injury, systemic inflammatory response syndrome, acute respiratory distress syndrome, and multi‐organ failure. Increased risk of comorbidities, such as stroke, myocardial infarction, autoimmune diseases, and non‐variceal gastrointestinal bleeding, was observed. TS patients had longer length of stay (LOS; 5.1 days vs. 4.5 days, p < 0.01) and displayed a mean additional $5382 (p < 0.01) in total hospital costs and a mean additional $20,083 (p < 0.01) in total hospitalization charges. In conclusion, hospitalization of patients with TS was associated with a significantly higher inpatient morbidity, mortality, expenditures, and longer LOS compared to non‐TS patients. Patients with TS had a higher risk of cardiovascular complications, autoimmune diseases, and gastrointestinal bleeding.
Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1
Authors: Mei Davide , Parrini Elena , Bianchini Claudia , Ricci Maria Luisa , Guerrini Renzo
Published: May 2023

Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in the GTPase and middle domains of the protein. We describe a 36‐year‐old man with autism and moderate intellectual disability who experienced only a few generalized seizures between the age 16 and 30 years. Using a whole sequencing approach, we identified the c.1994T>C p.(Leu665Pro) de novo novel missense pathogenic variant in the GTPase effector domain (GED) of the DNM1 protein. Structural analyses suggest that this substitution impairs both the stalk formation and its interactions, known to be important for the dynamin‐1 physiological cellular function. Our data expand the spectrum of phenotypes associated with pathogenic variants in the DNM1 gene, linking a variant in the GED domain with autism and onset in the adolescence of mild epilepsy, a phenotypic presentation remarkably different from the early infantile epileptic encephalopathy associated with pathogenic variants in the GTPase or middle domains.
Determining the association of insurance coverage and survival outcomes in patients with olfactory neuroblastoma utilizing machine learning
Authors: Fenton David , Diaz Ashley , Chen Haobin , Armstrong Mikhayla , Auger Samuel , Bujnowski Daniel , Pedroza Alena , Polster Sean , Das Paramita , Horowitz Peleg , Roxbury Christopher
Published: May 2023

Key points

We use machine learning to examine health insurance and mortality in olfactory neuroblastoma.

Private insurance significantly improved survival even after adjusting for confounders.

The regression model also found no statistical difference between Medicare and no insurance.
Whole‐genome sequencing study to identify candidate markers indicating susceptibility to type 2 diabetes in Bama miniature pigs
Authors: Niu Miaomiao , Zhao Yuqiong , Jia Yunxiao , Xiang Lei , Dai Xin , Chen Hua
Published: May 2023

Background

Hundreds of single‐nucleotide polymorphism (SNP) sites have been found to be potential genetic markers of type 2 diabetes mellitus (T2DM). However, SNPs related to T2DM in minipigs have been less reported. This study aimed to screen the T2DM‐susceptible candidate SNP loci in Bama minipigs so as to improve the success rate of the minipig T2DM model.

Methods

The genomic DNAs of three Bama minipigs with T2DM, six sibling low‐susceptibility minipigs with T2DM, and three normal control minipigs were compared by whole‐genome sequencing. The T2DM Bama minipig‐specific loci were obtained, and their functions were annotated. Meanwhile, the Biomart software was used to perform homology alignment with T2DM‐related loci obtained from the human genome‐wide association study to screen candidate SNP markers for T2DM in Bama miniature pigs.

Results

Whole‐genome resequencing detected 6960 specific loci in the minipigs with T2DM, and 13 loci corresponding to 9 diabetes‐related genes were selected. Further, a set of 122 specific loci in 69 orthologous genes of human T2DM candidate genes were obtained in the pigs. Collectively, a batch of T2DM‐susceptible candidate SNP markers in Bama minipigs, covering 16 genes and 135 loci, was established.

Conclusions

Whole‐genome sequencing and comparative genomics analysis of the orthologous genes in pigs that corresponded to the human T2DM‐related variant loci successfully screened out T2DM‐susceptible candidate markers in Bama miniature pigs. Using these loci to predict the susceptibility of the pigs before constructing an animal model of T2DM may help to establish an ideal animal model.
Simultaneous Generation of H2O2 and Formate by Co‐Electrolysis of Water and CO2 over Bifunctional Zn/SnO2 Nanodots
Authors: Hu Xin , Mei Guoliang , Chen Xiangxiong , Liu Jinlong , Xia Bao Yu , You Bo
Published: May 2023

Hydrogen peroxide (H2O2) and formate are important chemicals used in various chemical manufacturing industries. One promising approach for the simultaneous production of these chemicals is coupling anodic two‐electron water oxidation with cathodic CO2 reduction in an electrolyzer using nonprecious bifunctional electrocatalysts. Herein, we report an innovative hybrid electrosynthesis strategy using Zn‐doped SnO2 (Zn/SnO2) nanodots as bifunctional redox electrocatalysts to achieve Faradaic efficiencies of 80.6 % and 92.2 % for H2O2 and formate coproduction, respectively, along with excellent stability for at least 60 h at a current density of ≈150 mA cm−2. Through a combination of physicochemical characterizations, including operando attenuated total reflectance‐Fourier transform infrared spectroscopy (ATR‐FTIR), isotope labeling mass spectrometry (MS)/1H NMR and quasi‐in situ electron paramagnetic resonance (EPR), with density functional theory (DFT) calculations, we discovered that the Zn dopant facilitates the coupling of *OH intermediates to promote H2O2 production and optimizes the adsorption of *OCHO intermediates to accelerate formate formation. Our findings offer new insights into designing more efficient bifunctional electrocatalyst‐based pair‐electrosynthesis system for the coproduction of H2O2 and formate feedstocks.
Interfacial Ti−S Bond Modulated S‐Scheme MOF/Covalent Triazine Framework Nanosheet Heterojunctions for Photocatalytic C−H Functionalization
Authors: Gao Zhu , Jian Yi , Yang Song , Xie Qiujian , Ross Mcfadzean Charles Joseph , Wei Baosheng , Tang Juntao , Yuan Jiayin , Pan Chunyue , Yu Guipeng
Published: May 2023

Constructing photocatalyst systems to functionalize the inert C−H bonds has attracted extensive research interest. However, purposeful modulation of interfacial charge transfer in heterostructures remains a challenge, as it usually suffers from sluggish kinetics. Reported herein is an easy strategy to construct the heteroatom‐induced interface for developing the titanium‐organic frameworks (MOF‐902) @ thiophene‐based covalent triazine frameworks (CTF‐Th) nanosheets S‐scheme heterojunctions with controllable oxygen vacancies (OVs). Specifically, Ti atoms were first anchored onto the heteroatom site of CTF‐Th nanosheets, and then grown into MOF‐902 via an interfacial Ti−S linkage, generating OVs. Using in situ X‐ray photoelectron spectroscopy (XPS), extended X‐ray absorption fine structure (EXAFS) spectroscopy and density functional theory (DFT) calculations, the enhanced interfacial charge separation and transfer induced by moderate OVs in the pre‐designed S‐scheme nanosheets was validated. The heterostructures exhibited an improved efficiency in photocatalytic C3‐acylation of indoles under mild conditions with a yield 8.2 times larger than pristine CTF‐Th or MOF‐902 and enabled an extended scope of substrates (15 examples). This performance is superior to state‐of‐the‐art photocatalyst and can be retained, without significant loss, after 12 consecutive cycles.
Fused Triangulene Dimers: Facile Synthesis by Intramolecular Radical‐Radical Coupling and Application for Near‐Infrared Lasers
Authors: Shen Tong , Dijkstra Diego , Farrando‐Pérez Alex , Boj Pedro G. , Villalvilla José M. , Quintana José A. , Zou Ya , Hou Xudong , Wei Haipeng , Li Zhentao , Sun Zhe , Díaz‐García María A. , Wu Jishan
Published: May 2023

Large graphene‐like molecules with four zigzag edges are ideal gain medium materials for organic near‐infrared (NIR) lasers. However, synthesizing them becomes increasingly challenging as the molecular size increases. In this study, we introduce a new intramolecular radical‐radical coupling approach and successfully synthesize two fused triangulene dimers (1 a/1 b) efficiently. X‐ray crystallographic analysis of 1 a indicates that there is no intermolecular π‐π stacking in the solid state. When the more soluble derivative 1 b is dispersed in polystyrene thin films, amplified spontaneous emission in the NIR region is observed. Using 1 b as the active gain material, we fabricate solution‐processed distributed feedback lasers that exhibit a narrow emission linewidth at around 790 nm. The laser devices also exhibit low thresholds with high photostability. Our study provides a new synthetic strategy for extended nanographenes, which have diverse applications in electronics and photonics.
Carbon Nitride Pillared Vanadate Via Chemical Pre‐Intercalation Towards High‐Performance Aqueous Zinc‐Ion Batteries
Authors: Xu Yue , Fan Guilan , Sun Peng Xiao , Guo Yan , Wang Yangyang , Gu Xiaojun , Wu Limin , Yu Le
Published: May 2023

Vanadium based compounds are promising cathode materials for aqueous zinc (Zn)‐ion batteries (AZIBs) due to their high specific capacity. However, the narrow interlayer spacing, low intrinsic conductivity and the vanadium dissolution still restrict their further application. Herein, we present an oxygen‐deficient vanadate pillared by carbon nitride (C3N4) as the cathode for AZIBs through a facile self‐engaged hydrothermal strategy. Of note, C3N4 nanosheets can act as both the nitrogen source and pre‐intercalation species to transform the orthorhombic V2O5 into layered NH4V4O10 with expanded interlayer spacing. Owing to the pillared structure and abundant oxygen vacancies, both the Zn2+ ion (de)intercalation kinetics and the ionic conductivity in the NH4V4O10 cathode are promoted. As a result, the NH4V4O10 cathode delivers exceptional Zn‐ion storage ability with a high specific capacity of about 370 mAh g−1 at 0.5 A g−1, a high‐rate capability of 194.7 mAh g−1 at 20 A g−1 and a stable cycling performance of 10 000 cycles.
Effect of temperature on fatty acid composition in the Nile tilapia (Oreochromis niloticus): A temperature dependent nutritive lipid profile
Authors: Ullah Asad , Haider Muhammad Samee , Chan Malik Wajid Hussain , Aslam Sadar , ‐e‐Zehra Lakht , Tarar Omer Mukhtar , Saleem Nida , Arija Victoria
Published: May 2023

In this study, the effects of temperature on the fatty acids profile and the effects of temperature on the degree of unsaturation of fatty acids of Oreochromis niloticus were investigated. The analysis was performed by gas chromatography. The study showed that there were large temperature variations (10.0–32.0°C) during the study period (January–December). The highest crude fat content was found in January (3380 mg/100 g) and the lowest in June (2050 mg/100 g). The fatty acids profile showed significantly different diversity (p < 0.05). Total saturated fatty acid (∑SFA) content ranged from 409.54 to 1297.61 mg/100 g, monounsaturated fatty acid (∑MUFA) from 207.68 to 665.81 mg/100 g, and polyunsaturated fatty acid (∑PUFA) from 175.12 to 972.23 mg/100 g. The ∑MUFA and ∑PUFA concentrations were highest in January and lowest in June, and the ∑SFA concentration was lowest in January and highest in June. EPA and DHA contents were highest in January (198.96 mg/100 g) and lowest in June (48.76 mg/100 g). The contents of omega‐3 (653.17 mg/100 g) and omega‐6 fatty acids (252.54 mg/100 g) were highest in January and lowest in June (ω‐3; 106.43 and ω‐6; 60.91 mg/100 g). It concluded that the degree of unsaturation of fatty acids increases with decreasing temperature. In this study, the nutritional quality of the FAs profile was assessed using lipid quality indices. The indices indicating dietary quality of lipids by their values: Atherogenic index (0.47), thrombogenic index (0.38), hypocholesterolemic to hypercholesterolemic (3.00), meat fat quality (6.78), ω6/ω3 ratio (0.39), PUFA/SFA (2.37), MUFA/SFA (1.62), PUFA/MUFA (1.46), and PUFA + MUFA/SFA (3.99). These values are within the recommended range, indicating that the lipid profile of O. niloticus has high nutritional quality, which can be further improved by harvesting the fish during the winter season. Due to the nutritional importance of O. niloticus, the culture of this species could have significant interest to the people of Karachi, especially the coastal communities. To promote the nutritional diet in local population, the government should support the aquaculture of Nile tilapia.
Comparative analysis of cellulose nanocrystals and cellulose nanofibrils on the physico‐chemical properties of polyvinyl alcohol/chitosan blend for sustainable food packaging
Authors: Fakraoui Oumaima , Ghorbel Nouha , Noirel Cyril , Royaud Isabelle , Arous Mourad , Ayadi Zoubir , Kallel Ali
Published: May 2023

The food industry's ever‐increasing need to substitute synthetic packaging materials has led to the development of eco‐friendly alternatives with improved physical and mechanical properties. The main objective of this work relates to the effect of adding different weight fractions (1, 3 and 5 wt%) of cellulose nanocrystals (CNC) and cellulose nanofibrils (CNF) on the morphological, thermal, structural, biodegradable and mechanical properties of PVA/Chitosan (CS) bio‐nanocomposites. The DSC and FTIR results reveal that PVA and Chitosan are compatible due to the strong interactions via hydrogen bonding, which are also proved by the tensile test. The water solubility test indicates the biodegradability of nanocomposites. Furthermore, CNF have significantly enhanced the mechanical properties of PVA/CS. Hence, PVA/CS/CNF nanocomposites can be efficiently utilized for bio‐based packaging materials, where good mechanical properties are prime requirements.