bluuebunny/crossref_metadata_2025 huggingface dataset:
N-terminal Pro-B-Type Natriuretic Peptide is a Myocardial Biomarker in Pulmonary Sepsis and Septic Shock
Authors: Tyurin I. N. , Protsenko D. N. , Kozlov I. A.
Published: October 2022

The objective: to study changes and prognostic significance of the blood NT-proBNP in the patients with pulmonary sepsis.

Subjects and Methods. The study included 34 patients aged 54.5 ± 2.9 years with pulmonary sepsis or septic shock. Lethality in the intensive care unit (ICU) was 47.1%. NT-proBNP, procalcitonin (PCT) levels, blood lactate and hemodynamic parameters were registered on the 1st day (stage 1) and on the 4th-5th day of the ICU stay (stage 2). Hemodynamics was assessed through transpulmonary thermodilution. The differences were considered statistically significant at p < 0.05.

Results: At stage 1, NT-proBNP level was 5,220 [1,380‒17,850] pg/ml, did not decrease (p = 0.726) at stage 2 and amounted to 1,760 [631‒847] pg/ml. At stage 1, NT-proBNP correlated with extravascular lung water index (rho = 0.445; p = 0.038) and systolic pulmonary artery pressure (rho = 0.414; p = 0.023). At stage 2, NT-proBNP correlated with PCT (rho = 0.569; p = 0.003), blood lactate (rho = 0.525; p = 0.001), and mean arterial pressure to norepinephrine dosage ratio (rho = -0.422; p = 0.035). At stage 1, NT-proBNP was no predictor of lethality in the ICU: OR 1.0000; 95% CI 1.0000-1.0001. At stage 2, NT-proBNP > 4,260 pg/ml (sensitivity 87.5%, specificity 94.4%) was a predictor of lethality: OR 1.0004, 95% CI 1.0000-1.0008, p = 0.046 (AUC 0.893, 95% CI 0.732-0.974). Any increase of NT-proBNP level (> 0 pg/ml) between stages 2 and 1 was a predictor of lethality (sensitivity 87.5%, specificity 94.4%): OR 119.0, 95% CI 9.7432‒1,453.4241, p = 0.0002 (AUC 0.903, 95% CI 0.751-0.977).

Conclusion: Patients with pulmonary sepsis are characterized by a significant increase of blood NT-proBNP. At stage 1, the biomarker correlated with pulmonary hypertension and moderate pulmonary edema and was no predictor of lethality. At stage 2, NT-proBNP correlated with the indices of infection and sepsis severity (procalcitonin, blood lactate, and mean arterial blood pressure/norepinephrine dosage ratio). At this stage, NT-proBNP levels greater than 4,000 pg/mL and/or any degree of increase in blood levels of the biomarker were both sensitive and specific predictors of a lethal outcome. Specific features of etiopathogenesis of BNP hyperproduction in pulmonary sepsis make it difficult to interpret the elevation of NT-proBNP as an indicator of septic cardiomyopathy but does not reduce its value as a sensitive and specific predictor of lethality.
Effect of Dexamethasone and Lidocaine on the Cytokine Profile and Bleeding during Endoscopic Rhinosinus Surgery
Authors: Pavlov V. E. , Pervakova M. Yu. , Kuznetsova D. A. , Blinova T. V. , Surkova E. A. , Lapin S. V. , Polushin Yu. S.
Published: October 2022

The objective: to evaluate the feasibility of using dexamethasone and lidocaine to potentiate the effect of anesthesia in patients with chronic polypous rhinosinusitis during functional endoscopic sinus surgery (FESS) interventions.

Subjects and Methods. Clinical data, blood serum samples were collected prospectively from 52 patients who underwent FESS intervention. The patients were divided into 3 groups: Control Group ‒ C (n = 26), anti-inflammatory drugs were not administered; Dexamethasone Group ‒ D (n = 13), dexamethasone was administered (0.10‒0.15 mg/kg); and Lidocaine Group ‒ L (n = 13), a 1% solution of lidocaine was administered intravenously. The following parameters were studied: IL-6, IL-10, IL-18, alpha1-antitrypsin, and ferritin.

Results. An increase of IL-6, IL-6/IL-10 was observed in Group C. An increase of IL-10 and a decrease of IL-6, IL-6/IL-10 were noted in Group D. In Group L, IL-6, IL-6/IL-10 did not change significantly. The intensity of bleeding was lower in Groups L (p < 0.001) and D (p < 0.05) versus Group C. Relative changes in the concentration of biomarkers within the normal range were detected in all groups.

Conclusions. Changes in the cytokine profile are insignificant in patients with chronic polyposis rhinosinusitis during FESS performed under combined anesthesia.

No convincing data on the need for intraoperative use of dexamethasone or intravenous lidocaine have been received.
Drug Therapy of Cognitive Dysfunction in Minimally Invasive Surgery during Anesthesia with Sevoflurane
Authors: Neymark M. I. , Shmelev V. V. , Rakhmonov A. A. , Nazarchuk E. A.
Published: October 2022

The objective: To conduct a comparative assessment of efficacy of Cytoflavin and Cellex for management of cognitive disorders after videolaparoscopic cholecystectomy performed under general inhalation anesthesia with sevoflurane.

Results. In three representative groups (n = 30) of patients, markers of inflammation (CRP and IL-6), levels of brain-specific proteins (S-100 and NSE) were studied. Neuropsychological testing were performed by using the MoCA test, frontal dysfunction test battery (FAB) by two stages (stage I ‒ on the eve of the operation, stage II ‒ on the 7th day of the postoperative period). In patients of Group I (n = 30), disorders of higher mental functions of the early postoperative period persisted, which served as the basis for finding ways to eliminate and manage the identified disorders. For this purpose, Cytoflavin was used in Group II (n = 30), and Cellex was used in Group III (n = 30).

Comparative characteristics of the level of brain-specific proteins revealed a statistically significant decrease at stage I in Groups II and III versus Group I. The lowest level of both NSE (by 1.45 μg/l, p = 0.041) and S-100 (by 10.1 ng/l, p = 0.044) was observed in Group III versus Group II. In addition, at the second stage of the study, the greatest severity of the inflammatory response was noted in Groups II and III of patients compared to Group I and this degree of severity could be potentiated by the ongoing drug therapy. If in Group I, disorders of higher mental functions persisted on the 7th day of the postoperative period, then as a result of the ongoing drug therapy in Groups II and III, it was possible to achieve significantly better results of neuropsychological testing.

Conclusion. Administration of drug therapy contributed to the improvement of higher mental function eliminating cognitive deficit in the early postoperative period.
Information Value of Calculated Hematological Indices in the Assessment of Cardiac Risk in Oncological Surgery
Authors: Sokolov D. A. , Kozlov I. A.
Published: October 2022

The objective: to study information value of the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in the cardiac risk assessment in abdominal oncological surgery.

Subjects and Methods. 94 patients of 68 [62‒73] years old who underwent elective surgery were examined.

Results. Cardiovascular comortbidity was diagnosed in 69 (73.4%) patients. 11 (11.7%) perioperative cardiovascular complications were registered. Cardiac mortality was 4.3%. Hematological indices were not associated with cardiovascular diseases (NLR: OR = 0.59‒1.42; 95% CI 0.14‒2.60; p = 0.29‒0.74, PLR: OR = 0.99‒1.00; 95% CI 0.97‒1.01; p = 0.31‒0.99). NLR and PLR were not predictors of cardiovascular complications (OR = 0.67; 95% CI 0.19‒2.37; p = 0.46 and OR = 1.00; 95% CI 0.99‒1.01; p = 0.68) and cardiac death (OR = 0.21; 95% CI 0.01‒8.05; p = 0.23 and OR = 0.99; 95% CI 0.98‒1.01; p = 0.79).

Conclusion. NLR and PLR cannot be recommended for the cardiac risk assessment in abdominal oncological surgery.
Some Aspects of Pituitary-Adrenal and Autonomic Nervous Systems Functioning in Patients with Chronic Consciousness Disorders
Authors: Rybakov G. Yu. , Kondratyeva E. A. , Tsentsiper L. M. , Denisova A. A. , Dryagina N. V. , Lesteva N. A. , Ivanova A. O. , Kondratyev A. N.
Published: October 2022

Patients with chronic disorders of consciousness (CDoC) have various variants of the pathological organization of functions including sympathetic hyperactivity and hormonal changes.

The objective: to determine the severity of paroxysmal sympathetic hyperactivity (PSH), the function of the pituitary-adrenal system in patients with CDoC.

Subjects and Methods. 54 patients with CDoC were enrolled in the study. Patients were randomized in the groups depending on assessment on the Coma Recovery Scale-Revised scale and CRS-R index calculation. PSH severity was assessed 7 times a day for two days. During the first week from the moment of admission, blood sampling was performed 7 times a day to study the levels of ACTH and cortisol.

Results. PSH syndrome was detected in all groups, there were no significant dependencies of its severity on the time of day. There were no significant differences in the levels of ACTH and cortisol during the day.

Conclusions: PSH syndrome is observed in most patients with CDoC. In patients with CDoC, the daily rhythm of ACTH and cortisol secretion are disrupted.
Inflammatory Response in Patients with Spontaneous Intracranial Hemorrhages
Authors: Tsentsiper L. M. , Dryagina N. V. , Terekhov I. S. , Aybazova M. I. , Rumyantseva M. V. , Petrov A. E. , Petrova A. O. , Kondratyev A. N.
Published: October 2022

Mortality and disability rates in spontaneous intracranial hemorrhages remain high despite medical advances. In recent decades, much attention has been paid to neuroinflammation as a typical response to brain damage. Inflammation plays an important role in the acute and chronic phases of the disease. The relationship between plasma and cerebrospinal fluid cytokines, as well as the factors affecting their ratios, is currently not completely clear.

The objective was to study the inflammatory response to spontaneous intracranial hemorrhage.

Subjects and Methods. 59 patients aged 18 to 72 years (48 ± 6) were enrolled in the study. Patients were admitted to the intensive care unit after an episode of spontaneous intracranial hemorrhage. The levels of interleukins in blood plasma were studied: 6, 8, 10, TNF-α, C-reactive protein,

blood leukocytes, and procalcitonin (by a semi-quantitative method). In the cerebrospinal fluid, the following parameters were evaluated: cytosis, protein, glucose, lactate, cytokines (6, 8, 10, TNF-α). Blood samples were collected on days 1, 2, 3, 5, 7, 9, 14, 21, 28, 35, and 45.

Results. Systemic inflammatory response developed in all patients from the first day of acute brain injury. The most significant response was formed by glial brain cells which was confirmed by high levels of cytokines in the cerebrospinal fluid, hundreds and thousands of times higher than blood levels of cytokines.

Conclusion. Levels of pro-inflammatory cytokines are predictors of an unfavorable outcome.
Assessment of Severity and Prediction of Outcomes in Premature Newborns Based on the nSOFA Scale
Authors: Mironov P. I. , Lekmanov А. U. , Amirova V. R. , Idrisova R. G.
Published: October 2022

The objective: to evaluate the applicability of the nSOFA scale as a predictor of an unfavorable outcome in premature newborns.

Subjects. The study was designed as retrospective and observational. The study enrolled 109 newborns with a gestational age of ≤ 32 weeks of pregnancy (birth weight 1,071 (772‒1,451) g, gestational age 29 (26‒32) weeks, 22 (20,4%) patients died. nSOFA scores were determined based on the first 72 hours after birth, and a peak values were used for analysis. Death was considered an unfavorable outcome.

Results. The nSOFA score > 3 was associated with a odds ratio = 2.5 (CI 1.39–4.64, p = 0.002) for an unfavorable outcome. The area under the ROC curve was 0.796 (95% CI = 0.763–0.827).

Conclusion. The nSOFA scale is an acceptable tool for measuring the severity of organ dysfunction and predicting mortality in premature newborns, regardless of the etiology of the disease.
UTILITY OF SURGICAL APGAR SCORE TO PREDICTPOSTOPERATIVE MORBIDITY AND MORTALITY IN LAPAROTOMY PATIENTS - A PROSPECTIVE STUDY
Authors: Parthiban Akshaya , Reza Shojai Ali , Agarwal Pooja , Vardey Mohit , Agarwal Mahima
Published: October 2022

Background:This Ten-point Surgical Apgar Score also known as the SAS score predicts postoperative mortality and morbidity in patients undergoing laparotomy. Method:50 patients undergoing laparotomy surgery were enrolled. 42 of these were emergency surgeries forintestinal obstruction,perforationperitonitis, subacute intestinal obstruction,penetrating injury,blunt injury to abdomen, ovarian cyst rest.8 cases were elective surgeries. The Surgical Apgar Score (SAS) was calculated intra-operatively based on estimated blood loss, lowest mean arterial pressure and lowest heart rate. Post-operative complications and mortality were recorded. Results:In our study 10 out of 12 patients in the high-risk group developed complications. In other words, 83.34%developed complications.7 out of18 patients belonging to the medium-risk group developed complications which is 38.8%.Only 5 out of 20 patients in the low-risk group suffered from complications. 75% of the patients in the low-risk groups did not have any major complications following the surgery. This was statistically significant with a p-value of 0.04. Conclusions:In our situation, laparotomy is still considerably high related with morbidity and mortality. The Surgical Apgar Score is excellent at classifying the postoperative risk of major complication following laparotomyusing straightforward and highly varying intraoperative measurements. The SAS score alarms the surgeon and empowers him to take proactive action19.
PHYSICOCHEMICAL PROPERTIES OF SILICA NANOPARTICLES AND HEALTH HAZARDS
Authors:   Department of Physics, Christ Church College, Kanpur, India., Prakash Singh Satya
Published: October 2022

Large-scale industrial production and global commercialization of Silica Nanoparticles in recent year had resulted in increased risk of human exposures. However, there is a lack of knowledge on the health and environmental effects of such substances and information on their handling and disposal is also frequently incomplete. The current article, review, the physicochemical properties of the different nanosized silica materials that can affect their interaction with biological systems. The article also discuss the biological mechanisms involve in generating toxicity of nanosilica (both crystalline and amorphous), genotoxicity, immunotoxicity, ecotoxicity, workplace exposure, handling practices and alternatives of disposal of silica aerogels nanoparticle.
Kultúraközvetítő intézmények a Covid és a világörökség reflektorában
Authors: Bagi Krisztina , Magyar Márton
Published: October 2022

A 2020 márciusában hazánkban is megjelent Covid19-pandémia az élet számos területén kifejtette negatív hatását. Érzékenyen érintette a kulturális szektort, mint például a színházakat, mozikat és a muzeális intézményeket, mint kultúraközvetítő intézményeket is. Néhányan bezártak, mások az online tér adta lehetőségeket is kihasználták. Jelen tanulmány bemutatja a „kulturális covid-sokkot”, másrészt az UNESCO világörökségi helyszínek adta hátér megítélését három budapesti muzeális intézmény példáján keresztül. Eredményeink szemléltetik, hogy a pandémia számos online program bevezetését generálta, amelyek újabb közönségbevonzó, közösségépítő, kultúraközvetítő eszközként ítélhetők meg a jelenlét kiállításokra is. A világörökség-státusz és a műemlékvédelem együttesen hat a működésre, ám nem ez az egyetlen faktor, amely a múzeumok pozitív megítélését elősegít.
Gerenciamento de projetos e empreendedorismo
Authors: Souza Thiago Camilo Silva de , Freitas Vérica , Marcolin Carla Bonato , Paula Verônica Angelica Freitas de
Published: October 2022

As Empresas Juniores (EJs) oferecem ao mercado diversos projetos de Consultorias, de acordo com as suas áreas de conhecimento. Cada EJ possui uma maneira particular para o planejamento e a execução dos projetos, sendo que as Abordagens Ágeis, como o Scrum, estão sendo cada vez mais utilizadas. Com isso, este artigo visa analisar a aplicação do framework no Gerenciamento de Projetos da Apoio Consultoria, Empresa Júnior dos cursos de Graduação em Administração e Gestão da Informação da Universidade Federal de Uberlândia (UFU), verificando como foi realizada a implantação, bem como a sua aplicabilidade. Para isso, foram realizadas entrevistas semiestruturadas com cinco pós-juniores que atuaram na Apoio durante e/ou após a implementação. As entrevistas foram transcritas e foi realizada a análise de conteúdo utilizando o software MAXQDA®. O estudo obteve como resultado que o Scrum ajudou na melhoria do gerenciamento e execução dos projetos da Apoio, fazendo com que as entregas fossem mais ágeis e assertivas, porém, não foi implantado em sua totalidade. Concluiu-se que, apesar das dificuldades durante a sua implementação, foi possível a abordagem ser adaptada para a realidade da Apoio.
A Influência das redes sociais no mercado alimentício:
Authors: Viana Larissa de Lima , Silva Suzete Augusta da , Moreira Vanessa , Rosa Gleice De Divitiis , Silva Junior Francisco Felinto da
Published: October 2022

A importância de um plano de marketing para a gestão estratégica de um comércio tem sido um tópico relevante nos últimos tempos. Podemos ter bons resultados nas mídias sociais, tendo uma boa estratégia de como alcançar. Com base em uma revisão de literatura acerca do que já foi produzido sobre a temática, este artigo tem como objetivo central realizar um estudo de caso em uma pizzaria localizada no município de Carapicuíba e analisar os impactos que as redes sociais (Instagram e Facebook) geraram na atração e retenção de clientes para o comércio. Uma página da empresa foi criada originalmente no Instagram e Facebook. Com isso, pôde-se avaliar o desempenho da página e analisar o perfil do cliente. Assim, conseguimos verificar a importância de implantar as redes sociais e do marketing digital, propondo um melhor alcance e maior visibilidade para a pizzaria.
Verification of ceftriaxone and determination of its concentration in blood serum by capillary electrophoresis in surgical patients
Authors: Larichev Andrey B. , Smirnova Anna V. , Slobodskaya Natalya A. , Kryuchkov Vasiliy B. , Vasiliev Andrey A. , Izyumov Nikita M.
Published: October 2022

Objective: to develop a method for verifying ceftriaxone and determining its concentration in blood serum by means of capillary electrophoresis. Materials and methods. The study used ceftriaxone sodium salt (CJSC Pharmaceutical Company "Lekko"), model mixtures of biological fluids (whole blood, serum and blood plasma) with different concentrations of ceftriaxone; clinical biological blood samples taken during breast surgery against the background of perioperative antibiotic prophylaxis. The concentration of ceftriaxone was determined by using a Capel-105M capillary electrophoresis system (CJSC Lumex, St. Petersburg, Russia). Results. An express method has been developed for the determination of ceftriaxone in blood serum (sample volume - 0.1 ml), which involves the use of a precipitant of protein substances - crystalline ammonium sulfate, extraction of the organic system chloroform - isobutanol in a ratio of 3: 1, re-extraction of the substance into a working electrolyte diluted with water, and subsequent electrophoresis on the device "Capel-105M". Method validation indicates its linearity, correctness, precision and specificity; the lower limit of quantitation is 0.1 µg/0.1 ml biological medium. The effectiveness of the technique was confirmed in a clinical trial by determining the concentration of ceftriaxone in the blood serum 30 minutes after intravenous administration of 1 g of the drug for the purpose of perioperative antibiotic prophylaxis. Conclusion. The method for the quantitative determination of ceftriaxone in blood serum, performed by using a capillary electrophoresis system (“Kapel-105M”), meets the established validation criteria. At the same time, the identification of the antibiotic is carried out under selective conditions and requires a minimum amount of the object, thereby reducing the amount of co-extractive substances in the samples, which, in combination with the method of stacking during electrophoresis, provides a high sensitivity of the technique. It can be recommended for analysis in clinical diagnostic laboratories.
Study of the antioxidant activity of the tuberous pea herb (Lathyrus tuberosus L.)
Authors: Sukhomlinov Yuri A. , Bubenchikova Ksenia R.
Published: October 2022

Objective: to study the antioxidant and antiradical activity of extracts from the tuberous pea herb. Materials and methods. The study object was tuberous pea herb collected in Kursk region in 2020-2021 during the flowering period of plants. The antioxidant and antiradical activities of aqueous and aqueous-alcoholic extracts from the herb of tuberous pea were investigated. Antioxidant activity was evaluated by titrimetric method based on the interaction of potassium permanganate and reducing substances contained in the extract from raw materials of tuberous pea herb. The antiradical activity was studied by spectrophotometric method according to the ability of extracts to inactivate 1,1-diphenyl-2-picrylhydrazyl. The content of phenolic compounds (direct spectrophotometry) in terms of chlorogenic acid and flavonoids (differential spectrophotometry) in terms of rutin was determined. The obtained data were processed by statistical analysis. Results. By the example of the use of different extractants: water and alcohol of different concentrations, we investigated their influence on the antioxidant and antiradical activity of tuberous pea herb. The analysis of the experimental data obtained showed that all the extracts studied have antioxidant and antiradical activity, with the maximum activity found in extracts obtained from the herb using 50% and 70% ethyl alcohol as an extractant. The maximum content of phenolic compounds and flavonoids was also found in the mentioned extracts, which indicates a correlation between the antioxidant activity and the content of phenolic compounds. Conclusion. The results of the conducted experimental study allow us to conclude that the tuberous pea herb harvested in the flowering phase can be considered as a promising medicinal plant raw material of antioxidant orientation.
State of knowledge and future research needs on microplastics in groundwater
Authors: Belkhiri Amélie Hoarau , Carre Florence , Quiot Fabrice
Published: October 2022

Microplastics (MPs) are widespread in aquatic and soil environments. This study targets the issue of MPs’ transfer from soil to groundwater. Scientific papers were collected and analyzed using a text-mining approach that classifies text segments. This allowed the identification of four research topics and the organization of the results into a summarizing table. Those four topics are sources of groundwater MPs, main types of MPs (physico-chemical properties, polymer units, shapes, and size), human exposure (mainly drinking water), and potential environmental and human effects. Compared to the research of MP on aquatic or soil compartments, scientific data on MP in groundwater are less substantial. Current results show a divergence due to differences in context (alluvial aquifer, fractured rock aquifer, karst aquifer, etc), collecting, sampling, and analytical methods. This divergence requires further research with standardized analytic protocols and reference materials. The associated research gaps were identified by using the same approach. The following five topics emerged: (1) the transfer of MPs from soil to underground, (2) the contribution of groundwater to drinking water microplastic pollution, (3) the interaction with other contaminants, (4) the human and environmental effects, and (5) the protective and remediation solutions.
Risk perception from the consumption of untreated drinking water in a small island community
Authors: Nik Hassan Nik Muhammad Nizam , Hunter Paul R. , Lake Iain R.
Published: October 2022

A small island community in Malaysia uses gravity-fed drinking water, and rejected water treatment by the authorities. This study was conducted to evaluate the community's risk perception towards their untreated water supply by interviewing one adult per household in four out of eight villages on the island. The survey asked questions on risk perception, socioeconomic characteristics, and perception of water supply quality. Water samples were collected from a total of 24 sampling locations across the four villages, and 91.7% of them were positive for E.coli. The study surveyed 218 households and found that 61.5% of respondents agreed to some degree that the water is safe to drink without treatment, while 67.9% of respondents disagreed to some degree that drinking tap water is associated with health risks, and 73.3% of respondents agreed to some degree that it is safe to drink directly from taps that are fitted with water filters. Using factor analysis to group the risk perception questions and multivariable GLM to explore relationships with underlying factors, the study found that older respondents, lower income level, positive water odour perception and positive water supply reliability perception lowers risk perception. The village of residence also significantly affects the risk perception level in the model.
Recent Applications of Bioinformatics in Target Identification and Drug
Discovery for Alzheimer’s Disease
Authors: Singh Sushil Kumar , Kumar Ashok , Singh Ravi Bhushan , Ghosh Powsali , Bajad Nilesh Gajanan
Published: October 2022

Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease characterized by progressive memory loss. The main pathological features of the disease are extracellular deposition of amyloid β (Aβ) plaques and intracellular neurofibrillary tangles composed of hyper-phosphorylated tau protein. The understanding of factors contributing to AD progression, number of molecular signatures, and the development of therapeutic agents played a significant role in the discovery of disease-modifying drugs to treat the disease. Bioinformatics has established its significance in many areas of biology. The role of bioinformatics, in drug discovery is emerging significantly and will continue to evolve. In recent years, different bioinformatics methodologies, viz. protein signaling pathway, molecular signature differences between different classes drugs, interacting profiles of drugs and their potential therapeutic mechanisms have been applied to identify potential therapeutic targets of AD. Bioinformatics tools were also found to contribute in the discovery of novel drugs, omics-based biomarkers, and drug repurposing for AD. The review aims to explore the applications of various advanced bioinformatics tools in the identification of targets, biomarkers, pathways, and potential therapeutics for the treatment of the disease.
Bearing Capacity of Large Drilled Shafts Fully Embeded in Claystone and Sandstone Layers
Authors: Al Marwaji Muhammad , Arifin Yulian
Published: October 2022

This paper focuses on analyzing the bearing capacity of large diameter drilled shafts that are fully embedded in the claystone and sandstone layers. The foundations used are the drilled shafts for the Pulau Balang bridge pylons built across the Balikpapan bay. Three bored pile foundations with a planned diameter of 2 meters by 60 meters were used. The bearing capacity of the foundation in the field was carried out using the Osterberg cell test. The bearing capacity of the upper side of the foundation is 32.77, 27.26, and 114.46 MN, and the lower parts are 26.98, 27.16, and 50.25 MN, respectively. The results show that the method closest to the upper part of the OC test is the method suggested by Kulhawy and Phoon, with a value of C = 0.5. As for the lower part, the closest approach is the combination of the Kulhawy and Phoon and the Rowe and Armitage methods. The combinations of methods that approximate the total bearing capacity of the field are the Kulhawy and Phoon (1993) and Rowe and Armitage (1987) methods for the dominant claystone layer, and the O'Neil and Reese (1993) and Rowe and Armitage (1987) methods for the main sandstone layer
Landslide Threat Analysis and Slope Reinforcement Method with Sheet Pile on Singaraja City Boundary Road – Mengwitani Km 37+900 Right
Authors: Wirasana I Made , Sinarta I Nengah , Armaeni Ni Komang
Published: October 2022

The trigger factor for landslides is due to high rainfall intensity and long duration and the drainage system on the slopes is not good, causing the soil to become saturated. The Singaraja–Mengwitani City road section every rainy season always occurs landslides due to the geometry of the road adjacent to the slope because it is in a hilly area, as well as a drainage system that does not function during the rainy season. Based on the results of the previous soil investigation, the road section is a type of silty clay due to weathering of the ancient Buyan-Beratan volcanic rocks. The research was conducted through a field investigation with 2 drill points in a depth of 30 m, and slope stability analysis with the help of Geoslope software obtained. The value of the existing slope safety factor was 0.939, while at the time of moderate rain for 6 hours it was obtained SF<0.332, this condition indicates that the slope will fail so that it needs to be strengthened. The reinforcement is carried out with steel sheet piles is 4.49 m with a total length of sheet piles used is 6.49 ~ 7 m, based on the results of the analysis after being given reinforcement of steel sheet piles the safety factor value is 1.674, while when it rains it is moderate for 6 hours at 1,210, the slope is declared stable/safe because SF>1.0
Going beyond common motivational strategies and teaching styles
Authors: Riandi Riandi
Published: October 2022

This paper aims to determine the styles of teaching and motivational strategies carried out by two teachers in Frank McCourt’s Teacher man (McCourt, 2005) and School of Rock, a film (Linklater, 2003). The comparative method is used in this study as an effort to take a scientific approach on literary works. The researcher sorted, dissected, and compared literary works in different settings to make meaning, to convey their feelings, sentiments, and concepts to the author himself as a reader. Based on the findings, teachers in Frank McCourt’s Teacher man (McCourt, 2005) and School of Rock, a film (Linklater, 2003) make their students interested in the material being discussed in class they are more likely to channel their own internal motivation towards education and end up learning more. Teaching beyond the curriculum standards should be viewed as incredible opportunity to create meaningful lessons that will capture the attention of all students. Keywords: motivational strategies, teaching styles, teaching
The Walters songwriter's emotions and feelings of “I love you so”
Authors: Puspitasari Monica Indriyani , Baity Aprilia Nurul , Jupply Donald
Published: October 2022

This study is aimed to analyze the Systemic Functional Language represented in “I Love You So” by The Walters through a transitivity system. The object of the study is taken from the lyric of the song “I Love You So”. This study uses a descriptive qualitative research method and note-taking technique by paying attention to the process used in the lyrics. The researchers of this study use triangulation to detect the validity of the data. The result of this study shows that the songwriter desires to convey his emotion and feeling to the woman depicted in the lyrics of the song “I Love You So”.Keywords: SFL, transitivity, The Walters
EVALUASI PEMANFAATAN LABORATORIUM DALAM MENINGKATKAN KOMPETENSI TATA KECANTIKAN KULIT MAHASISWA PRODI TATA RIAS UNIVERSITAS NEGERI MEDAN
Authors: Tarigan Christine Ulina , Budiastuti Emy
Published: October 2022

The purpose of this study was to determine the extent of laboratory utilization from the standpoint of planning, implementation, and evaluation which used CIPP (context, input, process, product) model in the management of the Beauty Education Study Program at State University of Medan. Research model using qualitative approach to evaluation the facilities and infrastructure, utilization, and the involvement of students, head of laboratory, laboratory assistants, and lecturers of facial care courses with facial electric technology which influence the student’s practical competency with data collected by interviews and documentation on 60 students of third semester in the practical of facial electric treatment courses because it had homogeneous characteristics and capabilities. Data analysis techniques used is descriptive analysis and the results of this study indicate that the tendency of laboratory utilization 31.67% are sufficient, laboratory facilities and infrastructure 33.33% are sufficient, laboratory utilization in practical implementation 33.33% are sufficient, the competence of students 33.33% are less. There is a positive relationship between the variable’s utilization of laboratory, laboratory facilities and infrastructure and the practical implementation of the students’ competencies generated by the value of α = 0.00. It means the availability of facilities and adequate practical implementation can improve cognitive, psychomotor and affective competencies of student.
TATA RIAS DALAM TOKOH TARI SIMO GRINGSING
Authors: Mahyanto Aditiya Rizki
Published: October 2022

Ki Ageng Gringsing merupakan tokoh ulama islam yang menyebarkan agama islam di pulau jawa khususnya di kabupaten Batang. Kesaktian Ki Ageng Gringsing yaitu beliau dapat menjelma menjadi ular simo, dan istrinya Nyi Ageng Gringsing dapat menjelma menjadi ular. Tari Simo Gringsing adalah bentuk tari tunggal, namun dalam penyajiannyajumlah penari tidak dapat di batasi. Tarian ini dapat disajikan dalam berbagai tokoh seperti, simo, peperangan antar kelompok, begal garong dengan macan, atau bisa juga dengan tokoh ki Ageng Gringsing.Dalam penampilannya Tari Simo Gringsing di iringi dengan gamelan, rebana, jidor, terompet serta tata rias busana agar sajian lebih menarik.
PENGEMBANGAN NASI BAKAR TOPPA LADDA SEBAGAI MAKANAN ALTERNATIF SUMBER ZAT BESI BAGI REMAJA PUTRI
Authors: Restiana Reza
Published: October 2022

Zat besi merupakan salah satu mineral yang sangat dibutuhkan oleh manusia. Zat besi berperan penting dalam pembentukan hrmoglobin di dalam sel darah merah. Kebutuhan zat besi bagi manusia berbeda-beda sesuai dengan usia dan jenis kelamin. Berdasarkan usia dan jenis kelamin, remaja putri memerlukan asupan zat besi lebih banyak dibandingkan yang lain. Hal ini dikarenakan remaja putri mengalami menstruasi, sehingga rmaja putri lebih rentan menderita anemia. Metode penelitian menggunakan RD (Research and Development) dengan model 4D yaitu define, design, develop, dan disseminate. Uji kesukaan dilakukan oleh 30 panelis tidak terlatih. Uji t dilakukan untuk menganalisis ada tidaknya perbedaan secara nyata dari masing-masing parameter. Hasil penelitian menunjukkan bahwa produk acuan dan pengembangan nasi bakar disukai oleh masyarakat. Hasil analisis uji t pada parameter warna, aroma, rasa, dan tekstur tidak ada perbedaan secara nyata.Kata Kunci: Makanan alternatif, Nasi bakar, Zat besi, Remaja putri.
Petanque: Apakah Direct Instruction dapat meningkatkan kemampuan shooting dan pointing atlet?
Authors: Putra Miftah FP , Kurdi Kurdi
Published: October 2022

Penelitian ini memiliki tujuan untuk mengetahui apakah penggunaan model direct instruction dapat meningkatkan kemampuan shooting dan pointing atlet petanque Papua. Untuk mencapai tujuan tersebut jenis penelitian tindakan (action research) akan digunakan dengan subjek penelitian adalah atlet petanque Papua yang diambil dengan teknik sampling total (n = 22). Terdapat tiga instrumen yang digunakan, yaitu tes (pointing dan shooting), lembar observasi, serta dokumentasi. Teknik analisis data yang digunakan adalah deskriptif dan uji t sampel berpasangan (dependent sample t test). Hasil penelitian menemukan penggunaan model direct instruction dapat meningkatkan kemampuan shooting dan pointing pada atlet petanque Papua. Selain itu, penerapan model DI juga disenangi oleh para atlet karena memadukan secara langsung angtara teori dengan praktik.                                                                    Petanque: Is Direct Instruction can improve the shooting and pointing abilities of athletes? AbstractThis research aimed to determine whether the use of direct instruction models can improve the shooting and pointing abilities of Papuan petanque athletes. The action research will be used with the subject of the study being the Papuan petanque athletes taken by total sampling technique (n = 22). There are three instruments used, namely tests (pointing and shooting), observation sheets, and documentation. The data analysis technique used is descriptive and dependent sample t-test. The results of the study found that the use of direct instruction models can improve shooting and pointing abilities in Papuan petanque athletes. Besides, the application of the DI model is also loved by athletes because it integrates directly between theory and practice.
Hambatan dan tantangan proses pelestarian budaya lokal dalam konteks seni tradisi pencak silat di tasikmalaya
Authors: Muslihin Heri Yusuf , Pranata Oyon Haki , Nurlaela Wulan , Cahyana Cahyana
Published: October 2022

Fakta-fakta di lapangan mengenai hambatan dan tantangan selama proses pelestarian budaya lokal. Seni tradisi pencak silat merupakan pendekatan proses yang diduga dapat memberikan stimulasi positif terhadap aspek perkembangan budaya lokal di Tasikmalaya. Penelitian ini dilakukan untuk mengetahui kontribusi seni tradisi pencak silat terhadap pengembangan budaya lokal. Penelitian ini menggunakan metode deskriptif kualitatif dengan survey design. Teknik pengumpulan data menggunakan observasi terstruktur, wawancara, catatan lapangan dan dokumentasi. Hasil yang didapatkan untuk paguron aliran seni tradisi pencak silat yaitu 40 paguron. Hambatannya adalah wawasan dan tingkat pengetahuan paguron serta SDM yang relatif terbatas pada adat kebiasaan yang diturunkan dari pendahulunya, sedangkan yang menjadi tantangan banyaknya jumlah paguron yang berbasis seni tradisi pencak silat, tetapi belum berkontribusi optimal dalam mengembangkan pelestarian budaya lokal serta prestasi pencak silat Tasikmalaya. PROCESS OF PRESERVING LOCAL CULTURE IN THE CONTEXT OF TRADITIONAL ART PENCAK SILAT IN TASIKMALAYA: BARRIERS AND CHALLENGES  AbstractFacts on the ground regarding barriers and challenges during the process of preserving local culture. The traditional art of pencak silat is a process approach that is thought to provide positive stimulation to aspects of the development of local culture in Tasikmalaya. This research was conducted to determine the contribution of the traditional art of pencak silat to the development of local culture. This study uses a qualitative descriptive method with a survey design. Data collection techniques used structured observation, interviews, field notes and documentation. The results obtained for the paguron of the traditional art of pencak silat are 40 pagurons. The barriers is the insight and level of knowledge of the paguron as well as the relatively limited human resources on the customs handed down from its predecessors, while the challenge is the large number of pagurons based on the traditional art of pencak silat, but have not contributed optimally in developing the preservation of local culture and the achievements of Tasikmalaya pencak silat.
Pengembangan rocking bike untuk mengoptimalkan keseimbangan tubuh pada anak usia dini
Authors: Alamsyah Wahyu Nugroho Catur , Sukamti Endang Rini , Kurniawan Faidillah
Published: October 2022

Penelitian ini bertujuan mengembangkan alat berupa rocking bike untuk mengoptimalkan keseimbangan tubuh pada anak usia dini sebagai alat bantu latihan yang dapat memberikan keefektifan. Metode penelitian menggunakan Research and Development (RD) dengan 8 tahapan, yaitu identifikasi potensi dan masalah, pengumpulan informasi, desain produk, pembuatan produk, validasi ahli, revisi produk, uji coba, produksi akhir. Teknik analisis data penelitian berbentuk deskriptif kualitatif dan kuantitatif yang di olah dengan menggunakan rumus presentase. Hasil penelitian menunjukkan kelayakan pengembangan rocking bike untuk mengoptimalkan keseimbangan tubuh pada anak usia dini dengan validasi ahli materi satu (87,5%), ahli materi dua (95,8%), ahli media satu (97,5%), ahli media dua (87,9%), uji coba lapangan dari segi materi (87,7%), dari segi desain alat (93,0%), dari segi materi dan alat dengan total (90,4%). Kesimpulan rocking bike dinyatakan layak digunakan sebagai alat bantu latihan untuk mengoptimalkan keseimbangan tubuh pada anak usia dini. DEVELOPMENT OF ROCKING BIKE FOR OPTIMIZING THE BODY BALANCE IN EARLY CHILDHOODAbstractThis research aims to develop a tool in the form of a rocking bike to optimize the body balance in early childhood as a training aid that can provide effectiveness. The research method used Research and Development (RD). The research steps were taken from Sugiyono's research consisted of 10 steps, the researcher only took a few steps: identification of potentials and problems, gathering information, product design, product manufacturing, expert validation, product revision, testing, final production. The data analysis used descriptive qualitative and quantitative techniques in the form of percentaes. The results show the feasibility of developing the rocking bike to optimize body balance in early childhood with the validation of material expert 1 at (87.5%), material expert 2 at (95.8%), media expert 1 at (97.5%), media expert 2 at (87.9%), field trials in terms of material at (87.7%), in terms of tool design at (93.0%), in terms of materials and tools with a total (90.4%). These results indicate that the rocking bikes can be used as an exercise assistance to optimize the body balance in early childhood.
Hubungan minat olahraga dan psychological well-being terhadap prokrastinasi peserta didik di sekolah menengah atas
Authors: Utami Desy Yunita , Kriswanto Erwin Setyo
Published: October 2022

Prokrastinasi akademik merupakan sebuah fenomena dalam dunia pendidikan yang cukup mengkhawatirkan pada masa sekarang. Hal ini menjadi hambatan besar dalam proses pembelajaran terutama di SMA. Penelitian ini bertujuan mengetahui pengaruh dan hubungan minat olahraga dan psychological well-being terhadap prokrastinasi. Populasi penelitian adalah peserta didik kelas XI SMA Negeri 1 Muntilan sebanyak 355 siswa. Menggunakan teknik purposive sampling didapatkan 101 siswa sebagai sampel. Pengumpulan data menggunakan kuesioner. Teknik analisis data menggunakan korelasi product moment dan analisis regresi linier berganda dengan variabel Minat olahraga (X1),  Psychological well-being (X2) sebagai variabel independen dan variabel dependen adalah Prokrastinasi (Y). Hasil menunjukkan bahwa sebagian besar peserta didik (80%) memiliki kecenderungan untuk melakukan prokrastinasi akademik. Pada hasil korelasi terdapat hubungan negatif minat olahraga dan psychological well-being dengan prokrastinasi, di mana rhitung sebesar -0,554 dan -0,164. Sedangkan hasil analisis regresi menggunakan taraf signifikansi 5% menunjukkan hanya variabel minat olahraga yang signifikan memengaruhi prokrastinasi dengan p-value = 0,000. The relationship between sports interest and psychological well-being towards procrastination of students at senior high school  AbstractAcademic Procrastination is a quite alarming phenomenon in education sector nowadays. It would be a big obstacle in learning process especially for High School Students.  The aim of this research are knowing about influence and relationship between the interest of doing physical exercises and psychological well-being to procrastination. The population of this research were 355 students of XI grade of SMAN 1 Muntilan.Using purposive sampling obtained 101 students as sample. Data analysis technique using product moment correlation and linear regression with Interest of Doing Physical Exercises (X1), Psychological well-being (X2) as independent variables and Procrastination (Y) as dependent variable. The results show that almost all of students (80%) have a trend to do academic procrastination. There is a negative correlation between interest of doing physical exercises and psychological well-being to procrastination, where the correlation coefficient shown -0,554 and -0,164 respectively. Meanwhile in regression analysis with 5% significant level shows only interest of doing physical exercises that significant influencing procrastination with p-value = 0,000.
Kesiapan mahasiswa pendidikan jasmani kesehatan dan rekreasi melaksanakan praktik kependidikan
Authors: Hastuti Tri Ani , Jatmika Herka Maya , Kalpikosari Yovita
Published: October 2022

Penelitian ini bertujuan untuk mengetahui kesiapan mahasiswa Program Studi Pendidikan Jasmani Kesehatan dan Rekreasi (PJKR) FIK UNY yang akan melaksanakan Praktik Kependidikan (PK) atau Pengenalan Lapangan Persekolahan (PLP) tahun 2020.Jenis penelitian ini adalah penelitian deksriptif kuantitatif dengan metode survei. Populasi penelitian ini adalah mahasiswa Prodi PJKR FIK UNY berjumlah 187 mahasiswa yang akan melaksanakan PK/PLP tahun 2020. Sampel yang diperoleh sebanyak 128 responden, pengambilan sampel dengan purposive sampling. Instrumen yang digunakan berupa angket. Hasil uji reliabilitas instrumen penelitian ini adalah 0,879. Hasil uji validitas dengan r tabel 0,325 dinyatakan dari 45 butir pernyataan gugur 13 butir sehingga untuk pengumpulan data penelitian sebanyak 32 butir. Teknik analisis data adalah deskriptif dengan persentase. Hasil penelitian kesiapan mahasiswa Prodi PJKR FIK UNY yang akan melaksanakan PK/PLP tahun 2020 dengan kategori sangat siap 13,28%, siap 12,5%, cukup siap 37,5%, kurang siap 32,81%, dan sangat kurang siap 3,91%. Readiness of physical education, health and recreation students to implement educational practices Abstract  This research aims to analyze students’ readiness level in educational practice or internship orientation program among the students of Physical Education, Health and Recreation (PEHR) study program in 2020. The research was descriptive qualitative research with survey method. The number of population in this research was 187 students of PEHR study program who participated in Educational Practice Program (EPP) or School Internship Orientation Program (SIOP) 2020. The sample collected in this research was 128 respondents; the sample was taken using a purposive sampling technique. The instrument used in this research was questionnaire. The result of reliability test of this research instrument was 0,879. The result of the validity test using r table 0.325 stated in 45 statements, 13 statements of fall with the total research data is 32 statements. The analysis technique used in this research was descriptive with a presentation. The result of the students’ readiness level in internship orientation program among the students of PEHR study program in 2020 shows that 13.28% of them were very ready, 12.5% of them were ready, 37.5% of them were quite ready, 32.81% of them were lack of preparation, 3.91% were very lack of preparation.