bluuebunny/crossref_metadata_2025 huggingface dataset:
Contratos de colaboración empresarial en el derecho comercial colombiano
Authors: Oviedo Albán Jorge
Published: May 2023

Este escrito tiene por objeto presentar algunas ideas y conclusiones en torno a lo que podría ser la regulación aplicable a los contratos de colaboración empresaria en el derecho comercial colombiano. Cabe advertir que se hará una referencia general a este tipo de figuras, como contratos de colaboración o consorciales, no obstante tener claro que, a la luz del derecho comparado, debe diferenciarse a los contratos de joint venture, consorcio, unión temporal, grupos de empresas, etcétera.
Una entidad sui géneris del derecho internacional : la Soberana Orden Militar de Malta
Authors: de Rávago Bustamante Enrique
Published: May 2023

En pleno tercer milenio de la era cristiana, la Soberana y Militar Orden Hospitalaria de San Juan de Jerusalén, de Rodas y de Malta, es una cofradía de origen medieval, inspirada en sentimientos altruistas y profundamente humanitarios, presente en numerosas sedes diplomáticas, así como en hospitales, centros de refugiados, salas de auxilio, campamentos, automóviles, navíos, trenes y aviones, donde asiste a heridos de guerra, emigrantes, refugiados, exiliados y otras personas desvalidas.
Plazo para laudar, su protocolización y registro y laudo por acuerdo de las partes
Authors: Cantuarias Salaverry Fernando
Published: May 2023

La mayor parte de las legislaciones arbitrales latinoamericanas, si no todas, reconocen la facultad de las partes para acordar, ya sea directamente o por remisión al reglamento de alguna institución arbitral, el plazo dentro del cual los árbitros deberán emitir el laudo arbitral final. A falta de acuerdo, la gran mayoría de estas legislaciones establecen un plazo supletorio. El tema del plazo dentro del cual los árbitros deberán adoptar el laudo arbitral final es de suma importancia, ya que la emisión de un laudo arbitral tardío puede generar la anulación del mismo e inclusive el restablecimiento de la competencia del poder judicial.
El control constitucional en el arbitraje
Authors: García-Calderón Moreyra Gonzalo
Published: May 2023

Para mí es sumamente grato presentar este artículo sobre arbitraje en el libro de homenaje al doctor Fernando de Trazegnies Granda, al haber sido él un propulsor y pionero en el dictado del curso de Arbitraje en las facultades de derecho de nuestro país. En efecto, se acababa de promulgar el Código Civil de 1984, en el cual se habían incorporado los contratos de cláusula compromisoria y compromiso arbitral (en el Libro VII denominado «Fuentes de las obligaciones») cuando el doctor de Trazegnies, árbitro internacional de reconocido prestigio y conocedor de las ventajas y bondades de este mecanismo de solución de controversias, el mismo que aún no se había desarrollado en nuestro país, tomó la iniciativa, en su calidad de decano de la Facultad de Derecho de la Pontificia Universidad Católica del Perú, de presentar al Consejo Universitario de dicha casa de estudios un proyecto sobre la enseñanza de esta novísima institución. Pronto logró que se aprobase y se procedió al dictado, por primera vez en una facultad de derecho del Perú, de un curso exclusivamente sobre la materia arbitral.
Reflexiones críticas sobre la doctrina Calvo
Authors: Garibaldi Oscar M.
Published: May 2023

Mi breve contribución a esta colección de ensayos en homenaje a Fernando está inspirada, en cierto modo, en el primer caso en que trabajamos juntos: la controversia entre Southern Peru Copper Corporation y el Estado peruano1 . En ese entonces no existía un tratado entre Estados Unidos y la República del Perú sobre protección a las inversiones. Por ende, la compañía no estaba amparada por las normas de tratamiento que dichos tratados normalmente contienen ni podía someter la controversia a un arbitraje internacional contra el Estado, como lo autorizan la mayoría de los tratados de ese tipo. El único recurso disponible para la compañía era acudir a los tribunales peruanos, agotar todos los recursos internos disponibles y, en caso de que no obtener satisfacción, tratar de persuadir al gobierno de Estados Unidos sobre el mérito de iniciar un reclamo diplomático ante el gobierno del Perú por violación de las normas de derecho internacional consuetudinario sobre el trato debido a los extranjeros.
Peru's foreign investment framework put to the test : a review of the jurisdictional award in Duke Energy International Peru investments N º 1 Ltd. vs. the Republic of Peru
Authors: Ali Arif Hyder
Published: May 2023

El fallo jurisdiccional del Tribunal en este arbitraje constituye el primer caso de prueba internacional del sistema de estabilidad jurídica del Perú. Ese fallo también sirve como guía importante en cuanto al alcance y efecto del marco de inversión extranjera de Perú. Las opiniones legales de Fernando de Trazegnies parecen haber sido fundamentales para la determinación jurisdiccional del Tribunal.
Un muerto en las fronteras : restricciones constitucionales a la inversión extranjera en el Perú
Authors: Lazarte Molina Jorge Eduardo
Published: May 2023

Quiero dedicar las siguientes páginas a tratar un problema al estilo que aprendí de Fernando de Trazegnies, como quien se enfrenta a la tarea de diseñar un ataúd para un muerto. Se trata de un problema del que adolece nuestro sistema legal, y que afecta diariamente a todos los extranjeros que buscan invertir cerca de las fronteras de nuestro país. Según veremos, se trata de una afectación que limita absurdamente la inversión extranjera dentro de los cincuenta kilómetros de nuestras fronteras, y constituye un verdadero muerto para el que urge un ataúd.
Comentario sobre Imágenes rotas. Imágenes reconstruidas
Authors: Guerra Arteaga Hugo
Published: May 2023

Fernando de Trazegnies no es, de ninguna manera, solo un abogado, pese a que así lo señala el membrete de su correspondencia personal. Tampoco es simplemente un jurista, tal como se reconoce en el Foro. Fernando de Trazegnies es, ante y por encima de todo, un filósofo que, a través del derecho, la historia y ahora la literatura, trata de esbozar no una visión académica del mundo, sino y especialmente las pautas para que cada quien estructure una interpretación de la vida, en sí misma.
Reseña
Authors: Gutiérrez Miguel
Published: May 2023

Carta de agradecimiento a Fernando de Trazegnies por parte de Miguel Gutierrez
La literatura como posibilidad de reunir lo fragmentado. Acerca de Imágenes rotas, de Fernando de Trazegnies
Authors: Pantigoso Manuel
Published: May 2023

Fernando de Trazegnies (Lima, 1935) es miembro de Número de la Academia Peruana de Derecho, de la Academia Peruana de la Lengua, de la Academia Nacional de Historia y del Instituto Peruano de Investigaciones Genealógicas. Obtuvo Mención Honrosa en el Primer Concurso Nacional de Cuento de la Asociación Peruano Japonesa por «La tranquilidad de espíritu» (1992), incluido en el libro Imágenes rotas, cuya primera edición es de 1992. Fue finalista en el concurso nacional de cuentos Premio Copé 1997 con «La joven griega» (1997). Entre sus obras destacan Ciriaco de Urtecho, litigante por amor (1980), En el país de las colinas de arena (1994), Atracción apasionada (2004) e Imágenes rotas (segunda edición, 2007).
Comentario sobre La responsabilidad extracontractual
Authors: Tunc André
Published: May 2023

Para comprender la importancia de este tratado, bastaría destacar que el Código Civil del Perú data de 1984 y que constituye uno de los códigos más recientes que existen, si no el más reciente, y que, por otra parte, el autor de la obra, antiguo decano de la Facultad de Derecho, ha sido miembro de la Comisión Reformadora y el ponente de la sección encargada de la responsabilidad civil. El lector encuentra, entonces, en este trabajo, el comentario más autorizado del fruto del más reciente esfuerzo colectivo de elaboración de un derecho de la responsabilidad civil que debe adecuarse al mundo contemporáneo.
La Comunidad Europea: relaciones económicas con América Latina
Authors: Peláez Marón José Manuel
Published: May 2023

El artículo no presenta resumen.
Las nuevas reglas del GATT y la Organización Mundial de Comercio
Authors: Guzmán-Barrón César
Published: May 2023

El artículo no presenta resumen.
La teoría de los actos unilaterales de los estados
Authors: Novak Talavera Fabián
Published: May 2023

El artículo no presenta resumen.
La privatización de la violencia y la responsabilidad penal individual de agentes no-estatales por crímenes de lesa humanidad : una apreciación crítica del sistema interamericano
Authors: Ramacciotti de Cubas Beatriz
Published: May 2023

El artículo no presenta resumen.
Perú y Brasil : hacia una asociación binacional
Authors: González-Vigil Fernando
Published: May 2023

El artículo no presenta resumen.
Sucesiones y testamentos en el derecho internacional privado
Authors: Zambrano Copello Verónica
Published: May 2023

El artículo no presenta resumen.
Constitución y política exterior
Authors: Maúrtua de Romaña Oscar
Published: May 2023

El artículo no presenta resumen.
Política exterior del Perú durante el gobierno militar
Authors: Velit Granda Juan
Published: May 2023

El artículo no presenta resumen.
La contratación entre estados y empresas transnacionales
Authors: Novak Talavera Fabián
Published: May 2023

El artículo no presenta resumen.
Cooperación internacional y desarrollo en las Naciones Unidas
Authors: Ugarte Vega-Centeno Máximo
Published: May 2023

El artículo no presenta resumen.
Los principios generales del derecho : la buena fe y el abuso del derecho
Authors: Novak Talavera Fabián
Published: May 2023

El artículo no presenta resumen.
Algunas notas sobre la jurisprudencia de la Corte Internacional de Justicia
Authors: Soberón Garrido Ricardo
Published: May 2023

El artículo no presenta resumen.
Aspectos del derecho internacional de la guerra naval
Authors: García-Corrochano Moyano Luis
Published: May 2023

El artículo no presenta resumen.
Los intereses marítimos del Perú : una visión resumida
Authors: Brousset Barrios Jorge
Published: May 2023

El artículo no presenta resumen.
Los derechos humanos en la formulación de la política exterior de los Estados Unidos : el caso del Perú
Authors: Mantilla Falcón Julissa
Published: May 2023

El artículo no presenta resumen.
Venezuela y el MERCOSUR : ventajas estratégicas de las relaciones venezolano brasileñas
Authors: Morales Manzur Juan Carlos
Published: May 2023

El artículo no presenta resumen.
La contribución de los canales interoceánicos al derecho internacional económico : una aproximación a partir del comercio marítimo internacional de los países andinos por el Canal de Panamá
Authors: Candela Sánchez César
Published: May 2023

El artículo no presenta resumen.
Los refugiados y desplazados internos en Afganistán y la evolución del actual sistema internacional de protección de refugiados: algunos apuntes
Authors: Valdez Arroyo Flor de María
Published: May 2023

El artículo no presenta resumen.
Reflexiones acerca del tema de las fuentes del ordenamiento jurídico de la Comunidad Andina
Authors: Castro Bernieri Jorge
Published: May 2023

El artículo no presenta resumen.
La democracia y el sistema interamericano : de la Carta de la OEA a la Carta Democrática
Authors: Meza Salazar Sergio
Published: May 2023

El artículo no presenta resumen.
La cooperación judicial internacional en materia penal : el estatuto de Roma y la legislación nacional
Authors: Prado Saldarriaga Víctor
Published: May 2023

El artículo no presenta resumen.
Los sistemas unilaterales de preferencias arancelarias y el principio de no discriminación en el derecho de la Organización Mundial del Comercio
Authors: Piérola Castro Fernando
Published: May 2023

El artículo no presenta resumen.
El Perú y la República Popular de China: otro puente de entrada a Asia
Authors: Berríos Martínez Rubén
Published: May 2023

El artículo no presenta resumen.
El pisco, denominación de origen peruana
Authors: Gutiérrez Gonzalo
Published: May 2023

El artículo no presenta resumen.
Los pueblos indígenas ante derecho internacional
Authors: Ponte Iglesias María Teresa
Published: May 2023

El artículo no presenta resumen.
La universidad como agente en la Cooperación Técnica Internacional: tareas pendientes
Authors: Bernuy Quiroga Leena Lucía
Published: May 2023

El artículo no presenta resumen.
El modelo social instaurado por la Constitución Europea: un análisis desde la perspectiva de la protección de la salud pública
Authors: Kühn Baca Werner
Published: May 2023

El artículo no presenta resumen.
Derechos humanos y mujer inmigrante : una perspectiva española
Authors: Pérez Vera Elisa
Published: May 2023

El artículo no presenta resumen.
Los retos en el abordaje de la trata de personas desde la experiencia de los países andinos
Authors: Cortés Toro Dolores
Published: May 2023

El artículo no presenta resumen.
Apuntes acerca del Tribunal Internacional del Derecho del Mar : ¿Hamburgo v. La Haya?
Authors: Horna Ángel
Published: May 2023

El artículo no presenta resumen.
The competence of an arbitral tribunal under the Convention on the Settlement of Investment Disputes between States and Nationals of other States : an analysis of bilateral investment treaties provisions and a question of admissibility
Authors: Rey de Castro Alarco Álvaro Santiago
Published: May 2023

El artículo no presenta resumen.
La frontera como factor de integración regional. Análisis a partir del caso de la frontera entre Colombia y Perú
Authors: Londoño Niño Edgar Andrés
Published: May 2023

Este artículo tiene por objetivo resaltar la importancia de la frontera en los procesos de integración regional, haciendo referencia al caso de la frontera entre Colombia y Perú para demostrar la pertinencia de un entendimiento de frontera como factor de integración entre Estados vecinos. En primer lugar, se discutirá el origen y el entendimiento del término frontera. En segundo lugar, se analizará la diferencia entre límite y frontera para, en tercer lugar, abordar la importancia de la frontera como factor de integración y los elementos que soportan y justifican este enfoque. El artículo resalta que, como demuestra el caso de la frontera entre Colombia y Perú, el entendimiento negativo de la frontera debe ser superado por un entendimiento que resalte los factores comunes y la necesidad de establecer procesos de cooperación e integración entre países vecinos para el desarrollo de esas regiones y el bienestar de sus habitantes.
Assessment of the Effect of Conflicts on Yam Production Farms in Cross River State, Nigeria
Authors: Effiong John B.
Published: May 2023

Background: This study was designed to assess the effect of conflicts on yam production in Cross River State. The specific objectives of the study were to; identify the socio-economic characteristics of the respondents, assess the effect of conflicts on yam production in the study area and ascertain the constraints faced by yam farmers in the study area. Methods: The study adopted a multi-stage sampling technique. Three blocks were selected from each of the three Agricultural zones in the state. Three cells were randomly selected from each of the blocks sampled, which gave a total of twenty-seven (27) cells. A total of 450 respondents were selected for the study. Data were collected with the aid of a structured questionnaire. Data obtained were analysed using percentage, mean and standard deviation. Result: The result of the analysis revealed that a good number of the respondents had formal education and were married (53.6%). It was equally observed that conflicts reduced yam availability (X̄=2.50) decreased productivity (X̄=2.78), displaced farmers (X̄=2.68), caused hunger and starvation (X̄=2.62) and reduced arable land (X̄=3.08). The study also noted that the following constraints affected yam production in the study area include insecurity among yam farmers and communities (X̄ = 278), high cost of labour (X̄ = 2.55), lack of funds (X = 2.58) and fear of unexpected conflicts (X̄ = 2.71) among many others. The study recommended that civil defence Corp should be posted to conflicts zones in the state to provide security to the farming communities during farming seasons. The study therefore concludes that government needs to provide compensations to yam farmers who abandoned their farms as a result of conflicts and these would encourage them to return home for their yam business enterprises.
Comparative Spatial Distribution of Sucking Insect-Pest-Complex in Summer and Monsoon Cowpea [Vigna unguiculata (L.) Walp.]
Authors: Chhangani Gaurang , Mahla M.K. , Swaminathan R. , Dangi N.L. , . Lekha , Swami Hemant , Yadav Tara , . Ankur
Published: May 2023

Background: Pulse crops are known as an important dietary source of proteins for a major part of the vegetarian population across the globe; especially in India. Legume crops help restoration of soil fertility through symbiotic nitrogen fixation. Spatial distribution is an important aspect as it interprets the interaction between individuals of the species and their habitat. The biological reason of aggregation is highly unpredictable and it depends on behavioural pattern of the insect; therefore, spatial distribution accounts for informative description of organisms. Methods: In order to study the spatial distribution of sucking pests of cowpea, a field trial was laid out during Zaid and Kharif separately at the Instructional Farm of Rajasthan College of Agriculture, Udaipur in 2019 and 2020. Cowpea variety Pusa Komal was cultivated in 6 plots each of 3 m x 3 m with the row to row and plant to plant spacing of 50 cm and 10 cm, respectively. Different distribution pattern were used to determine spatial distribution pattern of species of insect fauna associated with cowpea during the summer and monsoon season. Result: The spatial distribution for most the insect pest complex was contagious during both the respective seasons. All positive IDM (index of clumping) values confirmed the clumping of the pest during the season. The mean crowding index was more than unity, indicated clumped interaction.
Exploring the User Experience of E-Thesis System: An Evaluation Using UX Honeycomb Method
Authors: Hariyanto Wahyu
Published: May 2023

This research article discusses the evaluation of the e-thesis information system in the Library and Information Science program at UIN Maulana Malik Ibrahim Malang. The background of this research is that the system is relatively new and is supported by several preliminary surveys conducted among users, most of whom are unfamiliar with the use of this e-thesis application system. The research population was taken from all students of the Library and Information Science Department in the 2018 and 2019 academic years, with a research sample of 50 students. The honeycomb method was used as the analysis tool for the evaluation, which emphasizes how UX can go beyond just usability aspects for users. The assessment aspects in the honeycomb method include useful, usable, desirable, findable, accessible, credible, and valuable. The research results showed that the overall average value of the e-thesis information system was 4.10, indicating that the e-thesis system is considered good in terms of its use. The highest score of 4.23 was found in the useful aspect, indicating that students agreed that the e-thesis information system could solve user problems and meet their needs. The lowest score of 3.93 was found in the accessible aspect, which needs improvement for future development of the information system. Indicators that need attention for improvement include less appealing design and the need to enhance capabilities. Suggested improvements include visual design, an advance search button, display of two thesis advisors, UI refresh, minimizing errors, and detailed schedule display on the homepage. Improving the existing features according to the research conducted can have a wide impact on the use of the information system and can be used continuously without errors.
Exploring human rights violations in post new era Indonesia
Authors: Tampubolon Manotar , Costanzo Giorgia
Published: May 2023

Although human rights have been officially recognized in Indonesia, human rights violations have persisted since Suharto's authoritarian regime. The purpose of this article is to examine why human rights violations that have occurred in Indonesia since the New Order era, when the Suharto regime was in power, but have yet to be resolved. With a human rights perspective, the author employs qualitative research methods in conjunction with secondary data from credible sources. Human rights violations committed during the New Order regime went unpunished, and impunity reigned. To this day, there are challenges to impunity for human rights violations in Indonesia, where the government does not have good faith to fulfil the rights of victims of human rights violations, and civil society organizations both on the national and international levels are powerless to support the resolution of these human rights violations. This situation will have an impact on Indonesia's international standing as one of the largest democratic countries that recognizes, protects, and fulfils human rights.
Animals in Caldecott Winners
Authors:   The Korean Society For Teaching English Literature, Kang Gyu Han
Published: May 2023

This article aims to discuss animal-focused Caldecott winners in order to explore the way in which anthropocentric perspectives are projected onto animals, the animal wildness erupts through artificial coverings, and animals and humans meet in the wild. The act of feeding and helping animals is based on a highly human-centered setting that makes animals live and feel happy even in hard conditions, as depicted in Make Way for Ducklings, The Big Snow, and Song of the Swallows. The relationship between Genevieve and Madeline in Madeline’s Rescue shows that animals have risen to the status of friends living together, instead of being typified as inferior creatures. On the other hand, references to zoo tigers in Madeline’s Rescue lead to rethinking of the meaning of animals located in a separate space called a zoo, unlike pets, as in The Biggest Bear, May I Bring a Friend?, A Sick Day for Amos McGee, and Finding Winnie: The True Story of the World’s Most Famous Bear. Zoos are exposed to the fundamental problems implied by the observation that the zoo animals have been deprived of wildness. The wild energy of the animal as a “living creature” breaks through the cracks of the homopocentric layers no matter how hard the layers try to cover the energy, which is portrayed in The Three Pigs, Where the Wild Things Are, Jumanji, and Tuesday. A possible union of an animal and a human is hinted in The Girl Who Loved Wild Horses, but it is almost impossible to capture the scene with human language. Owl Moon and Wolf in the Snow demonstrate how hard it would be to try to reach the reality of the animal in the wild under the cover of human language. Not relying on any other human language than onomatopoeia, which translates the sounds of animals into symbols as they are heard, Owl Moon and Wolf in the Snow trace meaningful encounters between animals and humans in the wild.
Children’s Picture Book and Cultural Representations of “We” Politics in We Are Water Protectors
Authors:   The Korean Society For Teaching English Literature, Han Kwangtaek
Published: May 2023

The present study aims to examine the cultural implications of “we” politics in both textual and visual representations in the 2021 Caldecott Medal-winning book We Are Water Protectors. Specifically, it focuses on the Korean translation of the book and its reviews, which emphasize the abstract notion of “we” while downplaying the political significance of “I” emphasized in the original work. This essay suggests that the writer and the illustrator highlight the importance of individual agency in social solidarity and resistance whereas the Korean translation obscures this theme by focusing solely on “we” politics. Through a comparative analysis, this study aims to explore the different cultural ideologies at work in the two versions in terms of global citizenship education and multiculturalism so as to indicate the complex interplay between cultural representation, language, and ideology in children’s picture book.
The Pliocene–Pleistocene transition in the subsurface of the Dutch-Belgian border region: insights from borehole Huijbergen
Authors: EVERAERT STIJN , DECKERS JEF , MUNSTERMAN DIRK , WESSELINGH FRANK P.
Published: May 2023

Cross-border correlations of the Pliocene–Pleistocene successions in the southern Netherlands and northernmost Belgium are problematic, because biostratigraphic markers are often lacking. Correlation is further hampered by the poor age constraints of the Belgian Merksplas Formation. To address these issues, sedimentary, mollusc and dinoflagellate cyst analyses are combined to characterise the lithostratigraphic units in the Huijbergen borehole (The Netherlands) and to provide age estimates. Subsequently, the Huijbergen borehole was correlated with nearby boreholes in Essen and Kalmthout (Belgium). The Piacenzian intervals of the Dutch Oosterhout Formation can be correlated with the Belgian Lillo Formation, with the latter’s threefold borehole log signature appearing virtually continuous across the border between both countries. The Dutch Maassluis and Waalre formations are correlated with the shell-bearing lower part and the unfossiliferous higher part of the Merksplas Formation respectively. Although dinocysts are not age-diagnostic for the Maassluis and Waalre formations in borehole Huijbergen, characteristic interglacial marine shells provide a Gelasian age assessment for the Maassluis Formation. By correlation, this age estimate can also be applied to the lower part of the Merksplas Formation, thereby elucidating the Pliocene–Pleistocene transition near the Dutch-Belgian border.
O imigrante japonês em São Paulo: na história e na pintura de Tomoo Handa
Authors:   Universidade Federal do Paraná, Oliveira Guilherme Nanini da Silva
Published: May 2023

A obra O imigrante japonês: história de sua vida no Brasil, de Tomoo Handa (1987), foi publicada pelo Centro de Estudos Nipo-Brasileiros (CENB). Esta obra é a referência utilizada nos estudos sobre a temática da imigração japonesa para o Brasil. Handa além de escrever sobre o imigrante japonês também o desenhou e pintou. Suas obras em número reduzido são preservadas pelo Museu da Imigração Japonesa, mas Handa também teve obras adquiridas por Mário de Andrade, hoje compondo o acervo de artes visuais do Instituto de Estudos Brasileiros da USP e tem obras pertencentes à Pinacoteca do Estado de São Paulo. O estudo proposto está em desenvolvimento e pretende abordar a forma como Handa representa o imigrante japonês, tanto pela linguagem gráfica quanto pela escrita.
A transdisciplinaridade na obra religiosa de Benedito Calixto: historiografia, arte e teologia
Authors:   Universidade Estadual de Campinas, Philippov Karin
Published: May 2023

O artista e historiador Benedito Calixto, que viveu entre 1853 e 1927, possui uma extensa obra religiosa que permite uma leitura transdisciplinar agregadora de valores histórico-historiográficos, artísticos e teológicos, dentro do contexto de sua ampla produção no início do século XX paulista, sobretudo no que concerne seu posicionamento artístico dentro da Igreja e da Primeira República. Desse modo, podem-se estabelecer pontos comuns entre o pensamento do artista historiador e aspectos teológicos inerentes ao Concílio Vaticano I, ainda oriundos do antigo Concílio de Trento (1545-1563), relativos à necessidade de encantamento e arrebatamento do fiel dentro do espaço sacro como a própria Igreja é e sacralizado pela arte de Calixto, em um Estado laico, desde a Constituição de 1891.
Entre tesselas e tons: o ressoar da devoção mariana na Basílica de Santa Maria Maggiore em Roma (século V)
Authors:   Universidade Federal do Espírito Santo, Campos Ludimila Caliman
Published: May 2023

A história da basílica de Santa Maria Maggiore esta envolta a poesia romana. Isso porque onde esta foi construída, ao topo do monte Esquilino, na vila romana Mecenas, teria sido palco de declamações de poemas de Virgílio, Horácio, Ovídio, entre outros. Quando o prédio da basílica foi erigido pelo epíscopo Libério (352-66), atribuiu-se a ela o nome de Sancta Maria ad Nives, pelo fato de estar nevando no início das obras. Restou a Sixto III (432 e 440), bispo de Roma, apenas a decoração interna e a inauguração da edificação, o qual foi dedicado em honra a Maria.
Blue: filmando poesia, pintando palavras
Authors:   Universidade Estadual de Campinas, Andreghetto Luiz Carlos
Published: May 2023

O cineasta britânico Derek Jarman (1942-1994), “herdeiro” das vanguardas artísticas dos anos 20/30 e intensamente influenciado pelo cinema underground e experimental dos anos 50/60, construiu uma poética fortemente amparada nos elementos pictóricos. Com um estilo visual singular - ao qual misturou passado e presente; teatro e pintura; artes performáticas e abstrações visuais; sexo e política – realizou um cinema com fortes marcas autorais e características experimentais-ensaísticas, frequentemente calcado na polêmica e na provocação ao establishment existente na época (Inglaterra, anos 80, então governo da primeira ministra Margaret Thatcher).
A obra de Agostino Balmes Odisio em Campinas
Authors:   Universidade Estadual de Campinas, Barrantes Paula Elizabeth de Maria
Published: May 2023

O artista Agostino Balmes Odisio nasceu em Turim, Itália, a 01 de maio de 1881. Foi registrado originalmente com o nome de Agostino Giuseppe Odisio, no entanto, em homenagem à genitora, cujo sobrenome era Balmes, passou a assinar seu nome como Agostino Balmes Odisio. No Brasil o nome sofreu pequena variação em virtude da sonoridade da língua, passando o artista a ser chamado, popularmente, de Agostinho Balmes Odisio. Ainda em Campinas, conforme está registrado no Livro do Tombo, o nome variou para Odissio Agostini.
A agricultura urbana e perirubana do município de São Paulo diante da pandemia de Covid-19
Authors: Leão Vitória Oliveira Pereira de Souza , Curan Roberta Moraes , Marques Paulo Eduardo Moruzzi
Published: May 2023

A pandemia Covid-19 gera impactos importantes na população mundial desde o início de 2020. As preocupações referentes ao abastecimento alimentar, notadamente das populações mais vulneráveis, ganharam destaque por parte de entidades internacionais, de órgãos públicos brasileiros, de pesquisadores e da sociedade civil. As dificuldades em responder à crise instaurada, especialmente pelo desalinhamento das ações amortecedoras nas diferentes esferas de poder brasileiras, agravadas por ameaças à democracia, compõem um quadro de ausência de plano público eficiente para a segurança alimentar e nutricional. Neste contexto, a agricultura urbana e periurbana (AUP), aliada a iniciativas fundamentadas na solidariedade alimentar, emerge como estratégica para o acesso ao alimento nas regiões urbanizadas mais vulneráveis, permitindo a manutenção de renda dos agricultores. O presente artigo visa lançar luz às diferentes ações de abastecimento alimentar no município de São Paulo no auge da pandemia, considerando especialmente novas dinâmicas em torno de sete agricultores urbanos e perirubanos paulistanos, representativos de situação nas principais regiões de produção em São Paulo. Além da articulação social entre diferentes grupos solidários do município, o papel dos circuitos curtos de proximidade na manutenção da produção local e na garantia do consumo alimentar de populações em situação de insegurança alimentar é destacado aqui, em quadro de grande insuficiência de políticas emergenciais de SAN.
Prediction of COVID-19 Using the Artificial Neural Network (ANN) with K-Fold Cross-Validation
Authors: Alifiah Nur , Kurniasari Dian , Amanto Amanto , Warsono Warsono
Published: May 2023

Background: COVID-19 is a disease that attacks the respiratory system and is highly contagious, so cases of the spread of COVID-19 are increasing every day. The increase in COVID-19 cases cannot be predicted accurately, resulting in a shortage of services, facilities and medical personnel. This number will always increase if the community is not vigilant and actively reduces the rate of adding confirmed cases. Therefore, public awareness and vigilance need to be increased by presenting information on predictions of confirmed cases, recovered cases, and cases of death of COVID-19 so that it can be used as a reference for the government in taking and establishing a policy to overcome the spread of COVID-19.
Objective: This research predicts COVID-19 in confirmed cases, recovered cases, and death cases in Lampung Province
Method: This study uses the ANN method to determine the best network architecture for predicting confirmed cases, recovered cases, and deaths from COVID-19 using the k-fold cross-validation method to measure predictive model performance.
Results: The method used has a good predictive ability with an accuracy value of 98.22% for confirmed cases, 98.08% for cured cases, and 99.05% for death cases.
Conclusion: The ANN method with k-fold cross-validation to predict confirmed cases, recovered cases, and COVID-19 deaths in Lampung Province decreased from October 27, 2021, to January 24, 2022.
 
Keywords: Artificial Intelligence, Artificial Neural Network (ANN) K-Fold Cross Validation, COVID-19 Cases, Data Mining, Prediction.
Security Aspect in Software Testing Perspective: A Systematic Literature Review
Authors: Awalurahman Halim Wildan , Witsqa Ibrahim Hafizhan , Raharjana Indra Kharisma , Basori Ahmad Hoirul
Published: May 2023

Background: Software testing and software security have become one of the most important parts of an application. Many studies have explored each of these topics but there is a gap wherein the relation of software security and software testing in general has not been explored.
Objective: This study aims to conduct a systematic literature review to capture the current state-of-the-art in software testing related to security.
Methods: The search strategy obtains relevant papers from IEEE Xplore and ScienceDirect. The results of the search are filtered by applying inclusion and exclusion criteria.
Results: The search results identified 50 papers. After applying the inclusion/exclusion criteria, we identified 15 primary studies that discuss software security and software testing. We found approaches, aspects, references, and domains that are used in software security and software testing.
Conclusion: We found certain approach, aspect, references, and domain are used more often in software security testing
 
Keywords: Software security, Software testing, Security testing approach, Security threats, Systematic literature review
MEGAnnotator2: a pipeline for the assembly and annotation of microbial genomes
Authors: Lugli Gabriele Andrea , Fontana Federico , Tarracchini Chiara , Milani Christian , Mancabelli Leonardo , Turroni Francesca , Ventura Marco
Published: May 2023

The reconstruction of microbial genome sequences by bioinformatic pipelines and the consequent functional annotation of their genes’ repertoire are fundamental activities aiming at unveiling their biological mechanisms, such as metabolism, virulence factors, and antimicrobial resistances. Here, we describe the development of the MEGAnnotator2 pipeline able to manage all next-generation sequencing methodologies producing short- and long-read DNA sequences. Starting from raw sequencing data, the updated pipeline can manage multiple analyses leading to the assembly of high-quality genome sequences and the functional classification of their genetic repertoire, providing the user with a useful report constituting features and statistics related to the microbial genome. The updated pipeline is fully automated from the installation to the delivery of the output, thus requiring minimal bioinformatics knowledge to be executed.
Linking environmental exposure and effects of pharmaceuticals on aquatic biota: state of knowledge in Latin America
Authors: Salgado Costa Carolina , Rimoldi Federico , Peluso María Leticia , Demetrio Pablo
Published: May 2023

The presence of pharmaceutically active compounds (PhACs) in the environment has been confirmed in different parts of the world, but mainly in North America and Europe. In Latin America, progress on this issue has not been as advanced, so we decided to compile the available information. The aim was to relate the environmental exposure of PhACs detected in fresh surface waters of Latin America, their bioaccumulation and lethal or sublethal effects. Most of the reported concentrations are in the same order of magnitude (113 PhACs in fresh surface water: 0.04-227,000 ng/L, 57 PhACs in aquatic biota: 0.02-652 ng/g d.w.) as those previously reported worldwide. The groups with the highest concentrations were analgesics/anti-inflammatories in water and antibiotics in biofilm. For effects, we found 67 no observed effect concentration (NOEC) values for 37 PhACs, 36 lowest observed effect concentration (LOEC) values for 26 PhACs and 45 lethal concentration (LC50) values for 31 PhACs. The only compound whose concentration in water exceeded the lowest LC50 value was acetaminophen (32,000 ng/L), which is an alarm signal for the need for further monitoring of this PhAC. In addition, acetaminophen, caffeine, carbamazepine, propranolol, 17α-ethinylestradiol and 17β-estradiol were the only PhACs with NOEC and LOEC values below the concentration in water. At the regional level, the information available in Latin America is scarce and becomes even scarcer when bioaccumulation in aquatic biota is considered. At the global level, little ecotoxicological information is available. This review identifies knowledge gaps and serves as a guide and reference for further decision-making.
Option Pricing: Examples and Open Problems
Authors: Halidias Nikos
Published: May 2023

The option pricing problem is equivalent with the hedging problem of the option, i.e. what the writer should do in order to hedge the risk that she undertakes selling a contract and moreover what is the probability of profit selling at a specific price. In other words, the writer first designs a way to hedge the risk and then prices the contract according to the amount needed to hedge that risk. The probability of profit is also a useful information for the buyer. The hedging strategy should be practically possible for the writer otherwise has no meaning. In this note we will discuss the option pricing problem and in particular the effect of the volatility on the binomial model which is a way to hedge practically a specific option in contrast to every pricing model that assumes rebuilding of the replicating portfolio continuously in time. In order to use the binomial model we have to modified it accordingly as we have seen in a previous paper. We also point out four open problems regarding the hedging problem.
Functional Biosimilarity to Replace Clinical Efficacy Testing of mAb Biosimilars: Advancing the FDA Perspective
Authors: Niazi Sarfaraz K.
Published: May 2023

The FDA has concluded that a biosimilar candidate capable of demonstrating pharmacodynamic biomarkers in a healthy subject need not be tested for clinical efficacy in patients, regardless of if the biomarker correlates with clinical response. Since monoclonal antibodies (mAbs) do not trig-ger pharmacodynamic response, they can be substituted with robust functional disqualifying them for this waiver that can be overcome by allowing comparison of functional properties that eventually result in clinical response. This suggestion is based on the FDA's preference for more sensitive testing methods. However, clinical efficacy testing in patients is the least sensitive method, as confirmed by statistical modeling, a fact that regulatory agencies need to admit. In this paper, I present a logical and rational argument to establish the biosimilarity of products that do not have pharmacodynamic biomarkers based on their orthogonally proven functional bio-similarity. This understanding will significantly lower the development cost of biosimilars, a goal that the FDA outlined in all its guidance.

Keywords: biosimilarity 1; biosimilars 2; pharmacodynamic biomarkers 3; monoclonal antibodies 4; FDA 5; clinical efficacy testing in healthy subjects 6; clinical efficacy testing in patients 7; functional assays 8; receptor binding 9.
Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice
Authors: Kunze Lea Helena , Ruch François , Biechele Gloria , Eckenweber Florian , Wind-Mark Karin , Dinkel Lina , Feyen Paul , Bartenstein Peter , Ziegler Sibylle , Paeger Lars , Tahirovic Sabina , Herms Jochen , Brendel Matthias
Published: May 2023

Neuroinflammation is one disease hallmark on the road to neurodegeneration in primary tauopathies. Thus, immunomodulation might be a suitable treatment strategy to delay or even prevent the occurrence of symptoms and thus relieve the burden for patients and caregivers. In the last years, the peroxisome proliferator-activated receptor γ (PPARγ) received increasing attention as it is immediately involved in the regulation of the immune system and can be targeted by the anti-diabetic drug pioglitazone. Previous studies have shown significant immunomodulation in amyloid-β (Aβ) mouse models by pioglitazone. In this study, we performed long-term treatment over six months in P301S mice as a tauopathy model with either pioglitazone or placebo. We performed serial 18 kDa translocator protein positron-emission-tomography (TSPO-PET) imaging and terminal immunohistochemistry to assess microglial activation during treatment. Tau pathology was quantified via immunohistochemistry at the end of the study. Long-term pioglitazone treatment had no significant effect on TSPO-PET, immunohistochemistry read-outs of microglial activation, or tau pathology levels in P301S mice. Thus, we conclude that pioglitazone modifies the time course of Aβ-dependent microglial activation, but does not significantly modulate microglial activation in response to tau pathology.
Modified Rice Bran Arabinoxylan as a Nutraceutical in Health and Disease – A Scoping Review with Bibliometric Analysis
Authors: Ooi Soo Liang , Micalos Peter S. , Pak Sok Cheon
Published: May 2023

Rice bran arabinoxylan compound (RBAC) is a polysaccharide modified by Lentinus edodes mycelial enzyme widely used as a nutraceutical. To explore translational research on RBAC, a scoping review was conducted to synthesise research evidence from English, Japanese, Korean, and Chinese sources while combining bibliometrics and network analyses for data visualisation. Ninety-eight articles on RBAC and the biological activities related to human health or disease were included. Research progressed with linear growth (median=3/year) from 1998 to 2022, predominantly on Biobran MGN-3 (86.73%) and contributed by 289 authors from 100 institutions across 18 countries. Clinical studies constitute 61.1% of recent articles (2018 to 2022). A shifting focus from immuno-cellular activities to human translations over the years was shown via keyword visualisation. Beneficial effects of RBAC include immunomodulation, synergistic anticancer properties, hepatoprotection, antiinflammation, and antioxidation. Cancer patients reported reduced side effects from chemoradiotherapy and improved quality of life in human studies, indicating RBAC’s impact on the psycho-neuro-immune axis. RBAC has been studied in 17 conditions, including cancer, liver diseases, HIV, allergy, chronic fatigue, gastroenteritis, cold/flu, diabetes, and in healthy participants. Further translational research on the impact on patient and community health is required for the evidence-informed use of RBAC in health and disease.
Effects of Cantharidin on Fish Erythrocytes, Tumor Cell Lines, and Marine Pathogenic Bacteria
Authors: Campos-Sánchez Jose Carlos , Guardiola Francisco Antonio , Esteban María Ángeles
Published: May 2023

Cantharidin, a toxic monoterpene secreted by blister beetles, has long been used in traditional Chinese and modern medicine for its unique properties. However, despite its widespread use, its effects on fish have not been studied in depth. The aim of this study was to evaluate the potential therapeutic applications of cantharidin in fish by examining its antioxidant, hemoagglutinating, hemolytic and cytotoxic activities at different concentrations (0, 0.625, 1.25, 2.5, 5 and 10 μg mL-1) in three different cell lines. In addition, the study explored the bactericidal and bacteriostatic properties of cantharidin against various fish pathogenic bacteria. The results revealed that there were no significant differences in antioxidant, hemagglutinating or hemolytic activities between the different concentrations of cantharidin tested. However, the study found that cantharidin exhibited dose- and time-dependent cytotoxicity in sea bream (Sparus aurata) erythrocytes and in SAF-1, PLHC-1 and Hela cell lines, resulting in morphological changes indicative of apoptosis. Interestingly, the highest dose of cantharidin tested demonstrated potent bactericidal activity against four marine fish opportunistic bacteria, including Vibrio harveyi, V. anguillarum, Photobacterium damselae and Tenacibaculum maritimum, but no statistically significant changes in bacteriostatic activity were observed against any of the bacteria tested. Overall, these results provide valuable information on the potential therapeutic applications of cantharidin in fish aquaculture. Further research is needed to fully understand the mechanisms of action and to explore possible preventive uses of cantharidin in fish.
Air Pollutants Impacts Asthma via the Tricellular Tight Junction Protein, LSR
Authors: Hwang Da-Yeon , An Min-Hyeok , Lee Pureun-Haneul , Kim Jung-Hyun , Nam Yunha , Park Shinhee , Baek Ae-Rin , Jang An-Soo
Published: May 2023

The tricellular tight junction protein angulin-1/lipolysis-stimulated lipoprotein receptor (LSR) is associated with numerous signal transduction pathways that regulate gene expression, epithelial cell function, and morphogenesis. The impacts of particulate matter on LSR and asthma are not known. Therefore, the aim of the present study was to assess the impacts of air pollution on LSR expression in asthma. To this end, we investigated the involvement of LSR in the pathogenesis of bronchial asthma in an ovalbumin (OVA) mouse model of asthma exposed to titanium dioxide (TiO2), and examined plasma LSR levels and their relationship with clinical variables in asthma patients and healthy controls. Plasma LSR levels were lower in asthma patients than in healthy controls. Although plasma levels of receptor for advanced glycation end-products (RAGE) were lower in asthma patients than in healthy controls, high mobility group box protein 1 (HMGB1) levels did not differ between these groups. In asthma patients, LSR levels were correlated with the forced vital capacity percentage, ratio of forced expiration (first second)-to-forced vital capacity, white blood cell count, and blood lymphocyte proportion. In mice, LSR expression was significantly decreased in OVA mice compared with control mice, and changed in OVA mice exposed to TiO2. Transforming growth factor beta levels were increased in OVA mice compared with control mice, and changed in OVA mice exposed to TiO2. Overall, plasma LSR levels were decreased in asthma patients, and were influenced by exposure to air pollution. These findings suggest the involvement of LSR in the pathogenesis of asthma.
Perspective on Air Quality Problems From Particulate Matter to the Health Crisis in Mainland Southeast Asia
Authors: Amnuaylojaroen Teerachai , Parasin Nichapa
Published: May 2023

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