bluuebunny/crossref_metadata_2025 huggingface dataset:
ОЦІНКА ХАРАКТЕРИСТИК ШУМУ НА РЕАЛЬНИХ ЗОБРАЖЕННЯХ З ВИКОРИСТАННЯМ ЗГОРТКОВОЇ НЕЙРОННОЇ МЕРЕЖІ НА МОБІЛЬНІЙ ПЛАТФОРМІ
Authors: Цехмистро Ростислав Вікторович , Абрамова Вікторія Валеріївна , Рубель Андрій Сергійович , Усс Михайло Леонтійович , Проскура Галина Анатоліївна , Рубель Олексій Сергійович
Published: July 2019

The subject of the study is the noise characteristics in real images obtained by mobile devices. The goal is to create a demo mobile application in Android platform, which realizes real-time estimation of noise characteristics in such images. Tasks: to investigate the accuracy of noise characteristics estimation by NoiseNet neural network on test images from the Tampere17 database; to conduct a preliminary study of the type, intensity and correlation characteristics of the noise in images obtained by mobile devices; to investigate the possibility of using NoiseNet to assess the noise characteristics in these images. The following results were obtained. Analyzing the noise characteristics in test images from the Tampere17 database, distorted by white Gaussian noise, it was shown that in general, the NoiseNet neural network demonstrates a rather high estimation accuracy (the relative error of evaluation does not exceed 0.2). However, for some images, in particular, highly textured, the value of relative error can be several times higher. The noise characteristics of images taken in various conditions by cameras embedded in mobile devices from various manufacturers were studied. It is shown that the noise in such images is signal-dependent and is often characterized by a high degree of spatial correlation. At the same time, the degree of spatial correlation of noise largely depends on lighting conditions of photo taking and is higher for images obtained in dim light. Since the NoiseNet neural network is not designed to work with spatially correlated noise, for its applying the images were preprocessed to eliminate the spatial correlation of noise. The ready-to-use NoiseNet neural network and the Android demo application for testing are available on the GitHub resource: https://github.com/radiuss/NoiseNet.
Analisa Perhitungan Muka Air Rata-Rata Di Lahan Gambut Dengan Tanggul Keliling Dalam Rangka Mengurangi Kebakaran
Authors: Putra Indra Setya , Lasmana Yudi
Published: July 2019

Peatland fires encourage the government to restore peat function as natural water storage. One of the measures taken is to build a circumference dike to hold water to reduce excessive drainage. However, there is no study yet of the planned average water level that has to be maintained from the construction of circumference dike. Therefore, the aim of this study is to calculate the average water level on peatlands inside the circumference dike. The methods used consist of hydrological analysis, spatial analysis, and water level analysis. The results of the analysis shows that the average water level in normal years tends to be above the surface, except in the second half of August to the first half of November. In the second half of September to the second half of October, the peat has the potential to be burned. In a dry season the water tends to fall decline to the drainage boundary of peatland which is at -1.5 m which occurs in the second half of March to December. In the second half of February until December peatland has potential to be burned. From this research, it can be concluded that the calculations using this method is similar with in-situ observation data and can be used to calculate the average water level of peat with the same conditions in other locations.
Modelling Wave Dissipation on Pile Breakwater Using Xbeach
Authors: Simanjuntak Eduardo Meyrianso , Eliasta Leo , Ginting Juventus Welly , Putra Ida Ayu Irawati Diah Ratna
Published: July 2019

Pile breakwater is an alternative coastal structure to prevent coastal erosion considering the economic and technical aspect. An improved design for pile breakwater is proposed here. Our goal is to develop an assessment tool in planning the implementation of pile breakwater. This tool is based on numerical model that has been verified with physical model result. The wave spectrum show that the numerical model is able to simulate the wave as same as the physical model with overestimation. It also points out that the simulation with wave period (T) = 2.5 s has more significant noise than the simulation with wave period (T) = 2 s. In general, the numerical model has high accuracy for predicting incident wave height (Hi), transmitted wave height (Ht) and transmission coefficient (KT) with error below 1 % RMSE. Xbeach is also able to simulate pile breakwater with high accuracy especially for two or three row arrangement with width gap 0.3 m. Even so, the numerical model have limitation regarding wave phase and wave through irregularity. Pile breakwater is an alternative coastal structure to prevent coastal erosion considering the economic and technical aspect. An improved design for pile breakwater is proposed here. Our goal is to develop an assessment tool in planning the implementation of pile breakwater. This tool is based on numerical model that has been verified with physical model result. The wave spectrum show that the numerical model is able to simulate the wave as same as the physical model with overestimation. It also points out that the simulation with wave period (T) = 2.5 s has more significant noise than the simulation with wave period (T) = 2 s. In general, the numerical model has high accuracy for predicting incident wave height (Hi), transmitted wave height (Ht) and transmission coefficient (KT) with error below 1 % RMSE. Xbeach is also able to simulate pile breakwater with high accuracy especially for two or three row arrangement with width gap 0.3 m. Even so, the numerical model have limitation regarding wave phase and wave through irregularity.
SISTEM INFORMASI MONITORING KESEHATAN MASYARAKAT BERBASIS WEB MENGGUNAKAN METODE UNIFED MODELLING LANGUAGE
Authors: Mukti Yogi Isro
Published: July 2019

Gerakan masyarkat sehat bebas dari sakit merupakan program yang terus ditingkatkan mulai dari pemerintah pusat sampai dengan daerah. Salah satunya melalui sosialisasi pentingnya hidup sehat, dengan cara mengetahui tentang informasi penyakit di daerah masing-masing. Penelitian ini bertujuan untuk menyedia sistem informasi monitoring kesehatan masyarkat berbasis web, guna mengetahui sebaran penyakit yang sedang berkembang di masyarakat seperti pneumonia atau radang paru-paru. Metode pengembangan sistem yang digunakan adalah web engineering, dengan perancangan menggunakan Unifed Modelling Language (UML), dengan menggunakan bahasam pemrograman PHP dan database MySQL
The Review Analysis of China’s Economic Growth and the Correlations with Thailand’s Economy
Authors: Supachart Wannakomol
Published: July 2019

This article was aimed to study the environment and the co-movement of China’s economic growth together with Thailand under economic and macro-finance dimensions by collecting information from academic literatures, global organization reports, and historical data from opened source database such as World Bank, United Nations, International Monetary Fund (IMF), and other relatives. The study found that China’s and Thailand’s economic activities are related particularly in term of trade but the low investment. In fact, services industry has replaced industrial manufacture to be the influent factor on gross domestic product (GDP) in both two countries. Moreover, enhancing to promote world- class capital markets and financial system development in China has drawn attraction from Thailand investors to invest more than a half of Thailand’s direct investment funds in financial firms and activities in China in 2017. In the conclusion, Thailand’s economic growth is still relied on China’s demand for raw materials according to goods and products they have exported to China. The suggestion for Thailand is to create their own technology like China’s development model in order to produce valuable goods and services productivity. And for both countries, China and Thailand should also have to focus on income distribution through other areas outside the city under the principal of economic development to improve the welfare of the population.
Pet godina primjene prava Europske unije
Authors: Duić Dunja , Petrašević Tunjica
Published: July 2019

Ulaskom u Europsku
uniju Republika Hrvatska obvezala se poštivati određena pravila 'igre' koja su
definirana i samim osnivačkim ugovorima (UEU i UFEU) i praksom Suda EU-a. U
prvom dijelu rada istražuju se pravni problemi s kojima se Republika Hrvatska
(dalje u tekstu: RH) susreće pri implementaciji i primjeni prava Unije nakon
što je postala punopravna članica EU-a. Cilj je prvoga dijela rada analizirati
u kojim područjima Europska komisija nalazi navodne povrede prava EU-a te će se
u tom kontekstu analizirati preporuke Europske komisije upućene RH i postupci
formalno pokrenuti na Sudu EU-a.
U drugom dijelu rada
analizirat će se primjena prethodnog postupka iz čl. 267. UFEU-a na hrvatskim
sudovima s posebnim osvrtom na prethodna pitanja koja su u proteklih pet godina
Sudu EU-a uputili hrvatski sudovi. Detektirat ćemo određene probleme i ponuditi
rješenja kako poboljšati suradnju hrvatskih sudova sa Sudom EU-a, a sve s
ciljem jedinstvena tumačenja i primjene prava EU-a.
‘The only learning I’m going to get’: Students with intellectual disabilities learning a second language through performative pedagogy
Authors: Piazzoli Erika , Kubiak John
Published: July 2019

Traditionally, adults with intellectual disabilities have not been given the option of participating in and thus benefiting from higher and post-secondary education. However, over the last number of years, an increasing number of inclusive tertiary educational programmes have come into existence. This article focuses on one such programme entitled Arts, Science and Inclusive Applied Practice delivered in the Trinity Centre for People with Intellectual Disabilities, School of Education, Trinity College Dublin, Ireland. The aim of this study was to consider the role of embodiment in supporting the Second Language Acquisition (SLA) process of a group of students with intellectual disabilities. The paper describes a project which integrated two of the programme modules – Italian for Beginners and Exploring Art: Renaissance to Modern. Findings presented support the use of a performative approach to second language learning for students with intellectual disabilities and sheds light on the connection between embodiment, language and learning in a performative key.
Ritz-Barr, Stephen (2017): Classics in Miniature – Joan of Arc. (Film)
Authors: Burton Leslie
Published: July 2019

The story of Joan of Arc has been told in every possible medium for over 600 years, and Stephen Ritz-Barr’s latest instalment Classics in Miniature, a series of short films featuring marionettes, is one of the latest takes on the legend. His previous projects present clear dramaturgical justification for the use of puppets; Faust2 (2008) has been a staple story in the repertoire of European puppet theatre for centuries, and so presents the story in a traditional format, while Quixote3 (2010) features a famous scene in which the Don single-handedly massacres an army of marionettes, and so takes a satisfying meta-theatrical turn as the central puppet himself encounters puppetry. The justification for the use of puppets in The Legend of Joan of Arc (2019) is less direct. While stories of saints' lives have been told through puppetry since at least the Middle Ages in Europe, and while it can certainly be argued that Joan's character is a metaphorical puppet, under the control of god, king, and country, the piece relies more heavily on the possibilities afforded by film, and the cinematography of Philip Klucsarits, than the possibilities afforded by puppetry. The framing, editing and visual effects are carefully crafted, at ...
Cytotaxonomy of four Floral Variants of Impatiens Balsamina L.
Authors: Dash Chandan Kumar , Rashid Md Harun Ar , Sultana Syeda Sharmeen , Rahman M Oliur
Published: July 2019

Karyomorphological characters were investigated in four floral variants of Impatiens balsamina L. viz. white, pink, violet and red for proper characterization and inferring relationships among them. All four floral variants of I. balsamina were found to possess 2n = 14 chromosomes, and ‘Simple Chromocenter Type’ of interphase nuclei was observed in all variants with many small heterochromatin blocks after orcein staining. ‘Continuous Type’ of prophase chromosomes was found in red variant, whereas both ‘Continuous and Gradient Type’ were found in other three variants. The red variant could easily be distinguished from the remaining three variants by total chromosome length, centromeric formula, average chromosome length, total form value, and karyotype asymmetry plus symmetry index. Based on karyomorphology, the white, pink and violet variants of I. balsamina were found very closely related and constituted with similar genome, whereas red variant was found to possess slightly modified genome and distinct from other three floral variants.

Journal of Bangladesh Academy of Sciences, Vol. 43, No. 1, 1-9, 2019
In Vitro Antagonism of Trichoderma Verede and Aspergillus Spp. against a Pathogenic Seed Borne Fungus of Sesame
Authors: Hosen Md Delwar , Shamsi Shamim
Published: July 2019

Four soil fungi were isolated from the soil by serial dilution and were identified as Aspergillus flavus Link, A. fumigatus Fresenius, A. niger van Tieghem and Trichoderma viride Pers. The soil fungi were selected to evaluate their antagonistic potential against seed borne fungus Fusarium merismoides isolated from sesame. In dual culture colony interaction Trichoderma viride showed the highest (45.88%) growth inhibiting effect on F. merismoides followed by A. niger (40.00%), A. flavus (36.37) and A. fumigatus (30.77%). Volatile metabolites from T. viride showed the highest growth inhibiting effect on F. merismoides (67.69%) and non-volatile metabolites from T. viride showed the highest growth inhibiting effect on F. merismoides (75.00%).

Journal of Bangladesh Academy of Sciences, Vol. 43, No. 1, 17-23, 2019
Trace Element Characterization in Household Dusts in Industrial Areas Along Highways in Bangladesh and their Health Implications
Authors: Khan Md Badiuzzaman , Islam Md Reazul , Begum Bilkis Ara , Miah Md Abdullah
Published: July 2019

A study was carried out in the industrial areas in order to determine the composition of trace elements in dusts deposited at homes, identifying different sources of elements and also for their possible health impacts. A total of 14 deposited dust samples were collected from households near industrial areas of Tangail and Gazipur districts during sampling campaign. Samples were analyzed using X-ray Fluorescence and the highest concentration was observed for Fe whereas the overall rank of the concentrations is Fe>Ca>K>Ti>Zn>Pb>Zr>Sr>Rb>Cu>Y>As>Cr>Ni. The Correlation analysis, enrichment factor and factor analysis indicated that anthropogenic sources especially industrial activity, vehicular emission and household cooking are the main sources of trace elements in the study areas. The non-carcinogenic and carcinogenic health risks indicated that children are more vulnerable for non-carcinogenic effects whereas the values of cancer risk for both the child and adult are below the acceptable limit of European Union.

Journal of Bangladesh Academy of Sciences, Vol. 43, No. 1, 47-58, 2019
Second Order Scheme For Korteweg-De Vries (KDV) Equation
Authors: Hafiz Khandaker Md Eusha Bin , Andallah Laek Sazzad
Published: July 2019

The kinematics of the solitary waves is formed by Korteweg-de Vries (KdV) equation. In this paper, a third order general form of the KdV equation with convection and dispersion terms is considered. Explicit finite difference schemes for the numerical solution of the KdV equation is investigated and stability condition for a first-order scheme using convex combination method is determined. Von Neumann stability analysis is performed to determine the stability condition for a second order scheme. The well-known qualitative behavior of the KdV equation is verified and error estimation for comparisons is performed.

Journal of Bangladesh Academy of Sciences, Vol. 43, No. 1, 85-93, 2019
Pembelajaran Inkuiri Terbimbing Berbasis Pratikum Pada Topik Pengukuran Untuk Meningkatkan Penguasaan Konsep dan Keterampilan Proses Sains Siswa SMP
Authors: Mahrun Mahrun , Permanasari Anna , Heliawati Leny
Published: July 2019

Abstrak: Penelitian kuasi eksperimen ini bertujuan untuk mengimplementasikan pembelajaran inkuiri terbimbing berbasis pratikum untuk meningkatkan penguasaan konsep dan keterampilan proses sains siswa pada topik pengukuran. Sebanyak 83 siswa SMP Kelas I terlibat dalam penelitian ini. Subjek penelitian dikelompokkan dalam kelompok eksperimen dan kelompok kontrol. Kelompok eksperimen mendapat perlakuan pembelajaran inkuiri berbasis peratikum sedangkan kelompok kontrol mendapat perlakuan pembelajaran berbasis pratikum. Penelitian ini menggunakan instrumen pilihan ganda untuk menjaring penguasan konsep siswa, sedangkan keterampilan proses sains dijaring dengan menggunakan tes esay. Hasil analisis menunjukkan bahwa pembelajaran inkuiri terbimbing berbasis praktikum pada topik penguran dapat meningkatkan penguasaan konsep dan Keterampilan Proses Sains (KPS) siswa. Peningkatan penguasaan konsep untuk kelas eksperimen adalah 54.58% sedangkan kelas kontrol adalah 26.60%. Peningkatan Keterampilan Proses Sains (KPS) pada kelas eksperimen sebesar 67.80% dengan kategori tinggi, sedangkan Keterampilan Proses Sains (KPS) kelas kontrol adalah 27.25% dengan katerogi sedang. Hasil analisis juga menunjukkan bahwa terdapat korelasi positif antara penguasaan konsep dan Keterampilan Proses Sains (KPS). Siswa juga memberikan tanggapan positif terhadap impelementasi pembelajaran inkuiri terbimbing berbasis praktikum.Kata Kunci: Pembelajaran Inkuiri, Pratikum, Penguasaan Konsep, Keterampilan Proses Sains
The Anticancer Agent Elesclomol Has Direct Effects on Mitochondrial Bioenergetic Function in Isolated Mammalian Mitochondria
Authors: Modica-Napolitano Josephine S. , Bharath Leena P. , Hanlon Alison J. , Hurley Liam D.
Published: July 2019

Elesclomol ((N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)); formerly STA-4783) is a mitochondria-targeted chemotherapeutic agent that has demonstrated efficacy in selective cancer cell killing in pre-clinical and clinical testing. The biologically active form of elesclomol is a deprotonated copper chelate (elesclomol:copper; E:C), which has been shown to enhance reactive oxygen species (ROS) production and induce a transcriptional gene profile characteristic of an oxidative stress response in vitro. Previous studies suggest that E:C interacts with the electron transport chain (ETC) to generate high levels of ROS within the organelle and ultimately induce cell death. The purpose of this study was to further explore the mechanism of cellular and mitochondrial toxicity of E:C by examining its direct effect on mitochondrial bioenergetic function. The results obtained indicate that E:C treatment in whole cells of non-tumorigenic origin at high concentrations (40 μM and higher) induces a rapid and substantial increase in mitochondrial superoxide levels and dissipation of mitochondrial membrane potential. Furthermore, similar higher concentrations of E:C act as a direct uncoupler of oxidative phosphorylation and generalized inhibitor of electron transport activity in isolated, intact mitochondria, and induce a dose-dependent inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity in freeze-thawed mitochondrial preparations. The results of this study are important in that they are the first to demonstrate a direct effect of the E:C chelate on bioenergetic function in isolated mammalian mitochondria, and suggest the possibility that the increase in ROS production and cytotoxicity induced by E:C may in part be due to uncoupling of mitochondrial oxidative phosphorylation and/or inhibition of electron transport activity. These results also provide important information about the mechanisms of mitochondrial and cellular toxicity induced by E:C and will ultimately contribute to a better understanding of the therapeutic potential of elesclomol as an anticancer compound.
Improving Employee Performance in Industrial Parks: An Empirical Case of Garment Enterprises in Binh Duong Province, Vietnam
Authors: Nguyen Thanh-Lam , Giang Pham Xuan
Published: July 2019

In responding to the current international integration and fierce competition on marketplace, over the last few decades, most businesses have tried to continuously improve their performance for better competitiveness. One of the preferred approaches is to enhance their employee performance; thus, fully capturing its determinants is critical. Thus, this study aimed at identifying key factors affecting employee performance so that businesses can create proper policies and actions to improve their overall performance. Specifically, as a common phenomenon, most employees working in industrial parks not only live far away from their workplaces as well as work a lot of overtime. These issues were carefully considered in this study to investigate their impacts on the employee satisfaction and performance. In the empirical case of garment enterprises in Binh Duong industrial parks, it was found that job satisfaction and employee performance are positively affected by eight factors: (1) reward and recognition; (2) development and training; (3) job promotion; (4) income; (5) work environment; (6) relationship with superiors; (7) relationship with colleagues; and (8) work procedure and role. In addition, it was found to be negatively affected by the house–work distance and overtime work, which are two new factors proposed in this study.
Structure-from-Motion (SFM) Photogrammetry as a Non-Invasive Methodology to Digitalize Historical Documents: A Highly Flexible and Low-Cost Approach?
Authors: Brandolini Filippo , Patrucco Giacomo
Published: July 2019

Historical documents represent a significant part of the world cultural heritage and need to be preserved from physical deformation due to ageing. The restoration of fragile documents requires economic resources that are often limited to only preserve the integrity of exceptional and highly valuable historical records. On the other hand, regeneration of ancient documents in digital form is a useful way to preserve them regardless of the material they are made of. In addition, the digitization of historical cartography allows creating a valuable dataset for a variety of GIS applications as well as spatial and landscape studies. Nonetheless, historical maps are usually deformed, and a contact-scanning process could damage them because this method requires planar positioning of the map. In this regard, photogrammetry has been used successfully as a non-invasive method to digitize historical documentation. The purpose of this research is to assess a low-cost and highly flexible strategy to digitize historical maps and documents through digital photogrammetry using low-cost commercial off-the-shelf sensors. This methodology allows training a wider audience of cultural heritage operators in digitizing historic records with a millimeter-level accuracy.
A Guide to Investigating Suspected Outbreaks of Mucormycosis in Healthcare
Authors: Hartnett Kathleen P. , Jackson Brendan R. , Perkins Kiran M. , Glowicz Janet , Kerins Janna L. , Black Stephanie R. , Lockhart Shawn R. , Christensen Bryan E. , Beer Karlyn D.
Published: July 2019

This report serves as a guide for investigating mucormycosis infections in healthcare. We describe lessons learned from previous outbreaks and offer methods and tools that can aid in these investigations. We also offer suggestions for conducting environmental assessments, implementing infection control measures, and initiating surveillance to ensure that interventions were effective. While not all investigations of mucormycosis infections will identify a single source, all can potentially lead to improvements in infection control.
Influence of Cementitious System Composition on the Retarding Effects of Borax and Zinc Oxide
Authors: Ataie Feraidon F.
Published: July 2019

This research investigated the retarding impact of zinc oxide (ZnO) and borax (Na2[B4O5(OH)4]·8H2O) on hydration of Portland cement, calcium aluminate cement (CAC), and calcium sulfoaluminate cement (CSA). Heat of hydration of cement paste samples with and without ZnO and borax was used to measure the influence of ZnO and borax on the set time of these cementitious systems. It was found that both ZnO and borax can retard the set time of Portland cement systems; however, ZnO was shown to be a stronger set time retarder than borax for these systems. ZnO did not show any retarding impact on CAC and CSA systems while addition of borax in these systems prolonged the set time. It was concluded that ZnO does not poison the nucleation and/or growth of CSA and CAC hydration products. We suggest that borax retards the cement set time by suppressing the dissolution of cement phases.
Suicide Risk in Bipolar Disorder: A Brief Review
Authors: Dome Peter , Rihmer Zoltan , Gonda Xenia
Published: July 2019

Bipolar disorders (BDs) are prevalent mental health illnesses that affect about 1–5% of the total population, have a chronic course and are associated with a markedly elevated premature mortality. One of the contributors for the decreased life expectancy in BD is suicide. Accordingly, the rate of suicide among BD patients is approximately 10–30 times higher than the corresponding rate in the general population. Extant research found that up to 20% of (mostly untreated) BD subjects end their life by suicide, and 20–60% of them attempt suicide at least one in their lifetime. In our paper we briefly recapitulate the current knowledge on the epidemiological aspects of suicide in BD as well as factors associated with suicidal risk in BD. Furthermore, we also discuss concisely the possible means of suicide prevention in BD.
Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells
Authors: Liu Meichen , Bai Xueyuan , Yu Shiting , Zhao Wenxue , Qiao Juhui , Liu Ying , Zhao Daqing , Wang Jiawen , Wang Siming
Published: July 2019

Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted as the major pathological mechanism of Alzheimer’s disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis represents the effective strategies in combating AD. Ginsenoside Re (Re) has pharmacological effects against Aβ-induced neurotoxicity. However, its molecular mechanism remains elusive. The present study evaluated the effect of Re against Aβ-induced cytotoxicity and apoptosis in SH-SY5Y cells, and investigated the underlying mechanism. We demonstrate that Re inhibits the Aβ-triggered mitochondrial apoptotic pathway, as indicated by maintenance of mitochondrial functional, elevated Bcl-2/Bax ratio, reduced cytochrome c release, and inactivation of caspase-3/9. Re attenuated Aβ-evoked reactive oxygen species (ROS) production, apoptosis signal-regulating kinase 1 (ASK1) phosphorylation, and JNK activation. ROS-scavenging abrogated the ability of Re to alter ASK-1 activation. Simultaneously, inhibition of JNK abolished Re-induced Bax downregulation in Aβ-challenged SH-SY5Y cells. In addition, Re enhanced activation of the nuclear factor-E2-related factor 2 (Nrf2) in Aβ-induced SH-SY5Y cells. Knockdown of Nrf2 by small interfering RNA targeting Nrf2 abolished the protective effect of Re. Our findings indicate that Re could be a potential therapeutic approach for the treatment of AD.
Anti-Biofilm Property of Bioactive Upconversion Nanocomposites Containing Chlorin e6 against Periodontal Pathogens
Authors: Zhang Tianshou , Ying Di , Qi Manlin , Li Xue , Fu Li , Sun Xiaolin , Wang Lin , Zhou Yanmin
Published: July 2019

Photodynamic therapy (PDT) based periodontal disease treatment has received extensive attention. However, the deep tissue location of periodontal plaque makes the conventional PDT encounter a bottleneck. Herein, upconversion fluorescent nanomaterial with near-infrared light excitation was introduced into the treatment of periodontal disease, overcoming the limited tissue penetration depth of visible light in PDT. Photosensitizer Ce6 molecules were combined with upconversion nanoparticles (UCNPs) NaYF4:Yb,Er with a novel strategy. The hydrophobic UCNPs were modified with amphiphilic silane, utilizing the hydrophobic chain of the silane to bind to the hydrophobic groups of the UCNPs through a hydrophobic-hydrophobic interaction, and the Ce6 molecules were loaded in this hydrophobic layer. This achieves both the conversion of the hydrophobic to the hydrophilic surface and the loading of the oily photosensitizer molecules. Because the excitation position of the Ce6 molecule is in the red region, Mn ions were doped to enhance red light, and thus the improved PDT function. This Ce6 loaded UCNPs composites with efficient red upconversion luminescence show remarkable bacteriological therapeutic effect on Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum and the corresponding biofilms under 980 nm irradiation, indicating a high application prospect in the treatment of periodontal diseases.
Identification of Quorum-Sensing Molecules of N-Acyl-Homoserine Lactone in Gluconacetobacter Strains by Liquid Chromatography-Tandem Mass Spectrometry
Authors: Liu Ling-Pu , Huang Long-Hui , Ding Xiao-Tong , Yan Lin , Jia Shi-Ru , Dai Yu-Jie , Xie Yan-Yan , Zhong Cheng
Published: July 2019

Many Gram-negative bacteria can regulate gene expression in a cell density-dependent manner via quorum-sensing systems using N-acyl-homoserine lactones (AHLs), which are typical quorum-sensing signaling molecules, and thus modulate physiological characteristics. N-acyl-homoserine lactones are small chemical molecules produced at low concentrations by bacteria and are, therefore, difficult to detect. Here, a biosensor system method and liquid chromatography-tandem mass spectrometry were combined to detect and assay AHL production. As demonstrated by liquid chromatography-tandem mass spectrometry, Gluconacetobacter xylinus CGMCC No. 2955, a Gram-negative acetic acid-producing bacterium and a typical bacterial cellulose (BC) biosynthesis strain, produces six different AHLs, including N-acetyl-homoserine lactone, N-butanoyl-homoserine lactone, N-hexanoyl-homoserine lactone, N-3-oxo-decanoyl-homoserine lactone, N-dodecanoyl-homoserine lactone, and N-tetradecanoyl-homoserine lactone. Gluconacetobacter sp. strain SX-1, another Gram-negative acetic acid-producing bacterium, which can synthesize BC, produces seven different AHLs including N-acetyl-homoserine lactone, N-butanoyl-homoserine lactone, N-hexanoyl-homoserine lactone, N-3-oxo-octanoyl-homoserine lactone, N-decanoyl-homoserine lactone, N-dodecanoyl-homoserine lactone, and N-tetradecanoyl-homoserine lactone. These results lay the foundation for investigating the relationship between BC biosynthesis and quorum-sensing systems.
The Antioxidant and Anti-Aging Effects of Acetylated Mycelia Polysaccharides from Pleurotus djamor
Authors: Li Huaping , Zhao Huajie , Gao Zheng , Song Xinling , Wang Wenshuai , Yuan Fangfang , Feng Yanbo , Zhang Yiwen , Zhang Jianjun , Zhang Shuliang , Jia Le
Published: July 2019

The present work mainly describes the preparation of acetylated mycelia polysaccharides (AMPS) from Pleurotus djamor and investigates the antioxidant and anti-aging effects in d-galactose-induced aging mice. The optimized procedure indicates the acetyl substitution degree of AMPS is 0.54 ± 0.04 under the conditions of a reaction time of 56 h, a reaction temperature of 37 °C, and 4 mL of added acetic anhydride. The in vitro analysis and in vivo animal experiments indicate that the AMPS could alleviate the aging properties by scavenging the radicals, elevating the enzyme activities, and reducing the lipid contents. As for serum levels, the AMPS can improve the serum biochemical indices and enhance immunological activity. The histopathological observations indicate that the injuries to the liver, kidney, and brain can be remitted by AMPS intervention. The characterization showed that AMPS was one kind of β-pyranose with the weight-average molecular weights of 3.61 × 105 Da and the major monosaccharides of mannose and glucose. The results suggest that AMPS can be used as a dietary supplement and functional food for the prevention of aging and age-related diseases.
Accident Trend Prediction of Heavy Metal Pollution in the Heshangshan Drinking Water Source Area Based on Integrating a Two-Dimensional Water Quality Model and GIS
Authors: Ding Xiaowen , Fang Ping
Published: July 2019

In recent years, water pollution accidents have frequently occurred, which have caused enormous economic loss and an adverse social impact. In this study, an accident trend prediction system was developed based on integrating a two-dimensional water quality model and GIS, and Arsenic (As) was adopted as a typical pollutant to study the temporal-spatial changes of heavy metal pollutions under different hydrological and meteorological conditions in the Heshangshan drinking water source area. The simulation for a recent accident indicated that pollutant changes were influenced by lateral diffusion, longitudinal diffusion, flow velocity, water flow, and the self-purification of the water body. It took 79.5 min for the As concentration to meet the water quality standard during the dry period, while it spent 61.3 min, 71 min, and 52 min in the impound period, falling period, and flood period, respectively. The emergency response times were 32 min (in the flood period), 38 min (in the impound period), 48 min (in the falling period), and 52 min (in the dry period). Furthermore, wind speed and wind direction also had impacts on pollutant spread. The times in which the maximum values met the water quality standard were 71 min (southeast wind), 77 min (southwest wind), and 87 min (no wind). The emergency response times were 38 min (southeast wind), 49 min (southwest wind), and 59 min (no wind). This study not only provides a reference for relevant departments and managers to carry out a risk assessment, disaster prevention, and emergency management after actual pollution accidents, but also makes up for the lack of research on the spatial-temporal change of heavy metal pollutants.
FAKTOR-FAKTOR YANG MEMPENGARUHI LABA BERSIH
Authors: Anggadini Sri Dewi
Published: July 2019

This research empirically examines partially the influence of operating cost and inventory turnover to net income and conducted on the food and baverages companies listed in Indonesian stock exchange period 2011-2015. The problems that occur are the decrease of net income despite the operating cost are decrease inventory and turnover are increased. This research uses descriptive analysis verification with the unit of analysis in this research is financial statement of the food and bavarages companies listed in Indonesian stock exchange period 2011-2015. And the population is 70 financial statements from 14 companies with sample select by using purposive sampling so obtained samples is 45 financial statements from 9 companies. Data analysis technique used is multiple linear regression analysis and helped by using application program SPSS statistics version 16. These results indicate that net income is influenced by operating cost with negative related, and inventory turnover is influenced with positive related. Partially inventory turnover has more dominant influence than the operating cost.
PERANAN AUDIT MANAJEMEN DALAM MENINGKATKAN EFEKTIVITAS PEMBERIAN KREDIT
Authors: Astuti Wati Aris
Published: July 2019

Tujuan dari penelitian ini untuk mengetahui peran audit manajemen terhadap penyaluran dana kredit dalam meningkatkan efektifitas pembiayaan kredit pada PT. BTPN KCP Burangrang Bandung. Metode penelitian menggunakan metode deskriptif verifikatif dengan pendekatan deskriptif. Data penelitian dikumpulkan dengan melakukan observasi, wawancara, menyerahkan kuesioner, dan melakukan penelitian kepustakaan. Teknik pengukuran statistik yang digunakan dalam penelitian ini adalah analisis korelasi rank spearman,  statistik solusi produk dan layanan (SPSS) 15,0 aplikasi dari windows untuk mendukung akuntansi manual.          Hasil penelitian bahwa peran audit manajemen  dalam meningkatkan efektifitas pemberian kredit memiliki arah yang sama, yang berarti semakin baik peran audit manajemen maka dalam pemberian kredit pun semakin baik atau baik.
ANALISIS SELISIH BIAYA PRODUKSI STANDAR DAN BIAYA PRODUKSI SESUNGGUHNYA PADA KOMPONEN PSF DAN D-NOSE PESAWAT A350 DIPT. DIRGANTARA INDONESIA
Authors: Octavia Evi
Published: July 2019

Tujuan penelitian ini adalah untuk menganalisis selisih biaya produksi standar dan biaya produksi sesungguhnya komponen PSF dan D-nose pesawat A350 pada PT. Dirgantara Indonesia. Penelitian ini dilatarbelakangi masalah yang dialami perusahaan yaitu biaya tenaga kerja langsung yang sudah ditetapkan oleh perusahaan tidak sesuai dengan realisasinya. Hal ini dapat dipengaruhi oleh biaya tenaga kerja yang melebihi jam kerja yang sudah di tetapkan oleh perusahaan, maka dari itu biaya sesungguhnya lebih besar dari biaya standar. Metode penelitian yang digunakan adalah metode deskriptif analisis dengan cara menemukan data dan fakta yang diperlukan. Data tersebut lalu dianalisis dan langsung disimpulkan serta diajukan beberapa rekomendasi atau saran yang dipandang perlu bilamana ada permasalahan yang perlu diselesaikan. Berdasarkan hasil praktik kerja di lapangan pada PT. Dirgantara Indonesia, bahwa PT. Dirgantara Indonesia menggunakan Job Order Costing dimana proses produksinya dilakukan sesuai dengan pesanan yang diminta oleh konsumen atau pemesan kepada perusahaan.
MEKANISME GOOD CORPORATE GOVERNANCE, LEVERAGE DAN KINERJA KEUANGAN PERUSAHAAN
Authors: Oktavia Evi
Published: July 2019

The purpose of this research is to explain an empirical evidence about the effect of GoodCorporate Governance (GCG) mechanism and leverage on financial performance, and definewhich of the most important variables having powerful impact on the firm financial performance.Good Corporate Governance mechanism measured by using board gender, board of directors,board of commissioner, audit committee, and institutional ownership variables. Leveragemeasured by using Debt to Equity Ratio (DER) variable, while financial performance measuredby using Return on Equity (ROE) variable. This research is using secondary data, such as thefinancial report, idx statistic report, and other related information of financial industry listed inIndonesia Stock Exchange for the period of 2011 to 2015. The sample used in this research were23 companies which selected by using purposive sampling method. In this study, panel dataregression methods have been conducted to explain the effect of GCG and leverage on the firmfinancial performance.The results show that board gender has a positive and significant effect on the firmfinancial performance. Meanwhile, boards of directors, board of commissioner, audit committeeand leverage haveno significant effect on the firm financial performance. Moreover, institutionalownership has a positive effect and no significant on the firm financial performance.
THE INFLUENCE OF NET PROFIT MARGIN AND CURRENT RATIO ON STOCK PRICE
Authors: Anggadini Sri Dewi , Tarsiah Eva
Published: July 2019

This research have purpose to examine empirically the effect on Net Profit Margin and Liquidity (Current Ratio) to Stock Price on Sub Sector Pharmaceutical Company Listed on IndonesiaStock Exchange Period 2012-2016. The problems that occur in Sub Sector Pharmaceutical Companyis the decrease of Stock Price but not followed by the increase of Net Profit Margin. Then the companyhas descreased Stock Price but not followed by the increase of Liquidity (Current Ratio). The research uses descriptive verification analysis method with population 10 companies from Sub Sector Pharmaceutical Companies. Sample selected by using purposive sampling, so thesample obtained to 8 companies with 40 financial reports from Sub Sector Pharmaceutical CompanyListed in Indonesia Stock Exchange Period 2012-2016. Technical of data analysis is multiple linearregression with SPSS 16.0 version as the application.  The result of the analysis showed that Net Profit Margin has positive and significant effect to Stock Price, and Liquidity which measured by Current Ratio has Positive dan significant effect toStock Price.
ACESSO DA POPULAÇÃO MASCULINA E UTILIZAÇÃO DOS SERVIÇOS DE ATENÇÃO PRIMÁRIA À SAÚDE EM BELO HORIZONTE – MG
Authors: Martins Alberto Mesaque , Modena Celina Maria
Published: July 2019

Trata-se de um estudo descritivo-exploratório, de caráter quantitativo que teve como objetivo descrever e analisar o padrão de acesso e utilização dos serviços de Atenção Primária à Saúde (APS) por homens na cidade de Belo Horizonte – Minas Gerais. Foram realizadas consultas ao Sistema de Informação de Gestão da Saúde, “Saúde em Rede”, que reúne dados dos prontuários eletrônicos de pacientes que utilizaram os serviços de APS do município nos anos de 2008 a 2011. Os resultados demonstram que os atendimentos masculinos correspondem a cerca de 33% das consultas realizadas na APS, revelando uma menor utilização em relação às mulheres. Observou-se uma maior número de consultas de homens idosos e adultos e, uma menor utilização pelos adolescentes e jovens. Quando relatado os motivos dos atendimentos, constata-se uma maior procura em casos de sintomas manifestos e diagnóstico de enfermidades. Faz-se necessário investir no aprimoramento dos sistemas de monitoramento de APS, buscando fomentar a construção de intervenções contextualizadas que possibilitem o reconhecimento das necessidades de saúde dos homens em cada território.
PERCEPÇÃO DOS USUÁRIOS INSULINO DEPENDENTES NÃO CONTROLADOS QUANTO AO TRATAMENTO PARA O DIABETES MELLITUS TIPO 2
Authors: Marques Camila Ruszkovski
Published: July 2019

O Brasil acompanha desde a década de sessenta o crescente envelhecimento populacional e o aumento da incidência das doenças crônicas não transmissíveis, dentre elas o diabetes mellitus (DM), que se caracteriza por uma disfunção crônica no metabolismo do indivíduo que não produz ou tem uma diminuída produção de insulina. Avaliar a percepção do paciente insulino dependente não controlado de uma unidade básica de saúde quanto aos cuidados necessários com a doença diabetes mellitus do tipo 2. Pesquisa qualitativa, descritiva e exploratória realizada em uma Unidade de Saúde, no período de Abril de 2014 a Junho de 2014 com 24 pacientes insulino dependentes com a glicemia não controlada. Encontrou-se com o estudo a falta de clareza a respeito da doença e de que cuidados como armazenamento dos insumos, rodízio dos locais de aplicação, tipos de seringas, cuidados com os pés, alterações como lipodistrofia, monitorização da glicemia capilar, homogeneização da insulina, atividade física, alimentação, entre outros, ainda é frágil, visto que o contato com o serviço de saúde acaba sendo por outros motivos que não de uma consulta de enfermagem regular para se trabalhar o autocuidado de maneira geral associado às doenças crônicas não transmissíveis. Concluiu-se com este estudo a importância da consulta de enfermagem quando se trata do autocuidado às doenças crônicas, pois o autocuidado é a chave para que se consiga prevenir e promover saúde à população, sendo assim observa-se a importância da Atenção Básica neste processo. Observou-se que o trabalho de educação em saúde para diabetes mellitus existe, mas ainda encontra-se frágil, sendo ainda mais observado o trabalhado com o autocuidado de pacientes diabéticos em ambulatórios de especialidades de grandes hospitais.Palavras-Chave: Diabetes mellitus; autocuidado; enfermagem
AS PRÁTICAS DE EDUCAÇÃO EM DIABETES VIVENCIADAS NO SUS: UMA DISCUSSÃO DA LITERATURA COM ÊNFASE NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Souza Luana de Oliveira , Figueiredo Wagner dos Santos , Machado Maria Lúcia Teixeira
Published: July 2019

O objetivo deste estudo foi apresentar e discutir as práticas de educação em saúde direcionadas aos portadores de diabetes produzidas no Brasil a partir da criação do SUS, com ênfase na Atenção Primária à Saúde. Tratou-se de uma pesquisa bibliográfica, e foram consultadas as principais bases de dados em saúde com interseções dos conjuntos dos termos: “educação em saúde”, “diabetes” e “Brasil”. Foram selecionados 22 trabalhos realizados em âmbito nacional, sendo 18 na Atenção Básica e 4 em outros níveis de atenção. Foram encontradas tanto práticas coletivas, como a educação em grupos, quanto individuais, como consultas, visitas domiciliares e monitoramento telefônico. Uma maior diversidade de formatos de práticas educativas foi identificada na Atenção Básica. Predominaram atividades multiprofissionais realizadas com idosos e que enfatizaram os temas: alimentação saudável, exercício físico e medicamentos. A maior parte das vivências baseou-se na relação dialógica e na abordagem educacional construtivista/ problematizadora, com tendências voltadas a concepção pedagógica de Paulo Freire. O grande desafio da educação em saúde está vinculado à formação profissional e ao processo de trabalho, portanto é essencial o papel de gestores de saúde no estímulo à capacitação dos profissionais para que possam desenvolver e ampliar habilidades de escuta e linguagem em futuras práticas educativas.
CONCEPÇÕES DOS ENFERMEIROS SOBRE A SAÚDE DO TRABALHADOR
Authors: Cossi Marcelly Santos , Medeiros Soraya Maria de , Costa Raphael Raniere de Oliveira
Published: July 2019

O estudo teve por objetivo identificar as concepções de enfermeiros da Atenção Básica sobre a saúde do trabalhador. Estudo do tipo analítico e de abordagem qualitativa realizado com 25 enfermeiros, por meio de questionário semiestruturado. Observou-se que o conceito de Saúde do Trabalhador foi dado em linhas gerais, comprovando que há deficiência no campo conceitual a este respeito. Entretanto, foi citada a importância de condições que contribuem para o desenvolvimento satisfatório do trabalho para evitar o adoecimento do trabalhador, evidenciando concepções que corroboram a mudança do modelo de atenção à saúde, com um olhar voltado para a promoção da saúde e prevenção do adoecimento do trabalhador. O conceito de Saúde do Trabalhador referido pelos sujeitos, apesar de simplificado no tocante às especificidades dessa parcela da população, revelou-se com uma dimensão ampla, abordando o trabalhador no seu âmbito físico, psíquico e social, sugerindo uma boa apreensão de acordo com o conceito ampliado de saúde.
ANÁLISE DAS CONDIÇÕES SANITÁRIAS DE UNIDADES DE SAÚDE DA FAMÍLIA COM BASE NO REFERENCIAL SOBRE PROCESSO DE TRABALHO
Authors: Barreto Helen Ingrid Vieira , De Souza Mariluce Karla Bomfim
Published: July 2019

Este estudo teve por objetivo analisar as implicações das condições sanitárias das Unidades de Saúde da Família (USF) tomando por referência os elementos constitutivos do processo de trabalho em saúde. O estudo foi realizado na capital do estado da Bahia, em 15 USF. Foram realizadas quinze entrevistas semiestruturada e um grupo focal. A análise do conteúdo apresentou-se em quatro categorias: agentes, objeto, meios e instrumentos, e finalidade. Os resultados apontam que as ações dos agentes com o objeto são dificultadas pela limitação do espaço físico, falta e inadequação dos materiais, e trabalho insalubre. Sobre os meios e instrumentos, identificou-se que as condições sanitárias de algumas USF dificultam a finalidade do trabalho. Neste sentido, os achados apontam para a necessidade de adequação da estrutura física, disponibilização dos recursos materiais de qualidade e priorização na agenda política sobre maiores investimentos na Atenção Básica, de forma a valorizar a ambiência das USF.