bluuebunny/crossref_metadata_2025 huggingface dataset:
Fractures of the Craniofacial Skeleton in the Elderly: Retrospective Studies
Authors: Michalak Piotr , Wyszyńska-Pawelec Grażyna , Szuta Mariusz , Hajto-Bryk Justyna , Zapała Jan , Zarzecka Joanna Katarzyna
Published: October 2021

The aim of the retrospective analysis of the medical documentation of 101 patients was to assess the incidence, etiology, and type of craniofacial fractures in the elderly population of southern Poland, who required specialist treatment at the Department of Cranio-Maxillo-Facial Surgery Jagiellonian University, Krakow, Poland, in the period 2010–2019. Patients were divided into 3 age groups: 65–74, 75–84, and 85 and older. The following was noted: age, sex, place of residence, education, cause and location of fracture, treatment, injuries and comorbidities, complications, alcohol and other drugs at the time of injury, and the period of hospitalization. The dominant group were patients aged 65–74 (72.28%), mainly males (56.44%). The main cause was fall (47.52%). The fractures involved mainly the mandible and the zygomaticomaxillary complex. Over half of patients (50.50%) lived in the countryside or small towns. Work tool-related accidents prevailed among geriatric patients living in small towns and rural areas. Craniofacial fractures were additionally accompanied by common complications regarding the organ of vision. Further studies analyzing factors leading to increased risk of craniofacial injuries in the elderly of the rural population will enable proper support programs, prophylaxis, and principles concerning agricultural activities.
Social Distancing in Tourism Destination Management during the COVID-19 Pandemic in China: A Moderated Mediation Model
Authors: Zhang Hui , Zhuang Min , Cao Yihan , Pan Jingxian , Zhang Xiaowan , Zhang Jie , Zhang Honglei
Published: October 2021

While protective measures in response to infectious diseases may reduce the freedom of tourists (regarding their behaviors), few studies have documented the effects of destination protective measures on the self-protective behaviors of tourists. By applying the protection motivation theory, this study examines the effects of perceived destination protective supports on the social distancing intentions of tourists during the COVID-19 pandemic. The results reveal significant relationships among perceived destination support, coping appraisal, threat appraisal, and the social distancing intentions of tourists. Moreover, two cognitive appraisals—toward the pandemic—partially mediate the relationship between perceived destination support and social distancing intention, and this mediational process is ‘intervened’ with by social norms. This has implications on whether tourist destinations apply more rigorous social distancing polices during the COVID-19 pandemic, to enhance the coping confidence behaviors of tourists, without causing anxiety and fear, and to achieve the goal of enhancing tourists’ intentions to protect themselves.
Threats to and Opportunities for Low-Income Homeownership, Housing Stability, and Health: Protocol for the Detroit 2017 Make-It-Home Evaluation Study
Authors: Mehdipanah Roshanak , Dewar Margaret , Eisenberg Alexa
Published: October 2021

Few studies have examined the combined effects of affordability, housing conditions and neighborhood characteristics on the housing stability and health of low-income homeowners. We begin to address these gaps through a mixed-method study design that evaluates the Make-it-Home program (MiH) in Detroit, Michigan, aimed at helping low-income tenants become homeowners when their landlords lose their homes to tax foreclosure. We compare the ‘intervened group’ of MiH homeowners to a ‘comparison’ group of similarly situated households whose homes experience property tax foreclosure at the same time. The comparison group represents the likely outcomes for the participants had they not participated the program. Participants will be surveyed twice (intervened group), or once (comparison group) per year over a three-year period, regarding their housing and neighborhood conditions, health, life events, and socio-economic status, including income and employment. We will use property and neighborhood census data to further examine the conditions experienced. The findings for policy and program development from this study are timely as the nation faces a chronic shortage of affordable housing for both purchasers and renters. The results suggest ways to improve the MiH program and lay out approaches for researchers to navigate some of the complexities associated with this type of research.
Vaping and COVID-19: Insights for Public Health and Clinical Care from Twitter
Authors: Majmundar Anuja , Allem Jon-Patrick , Unger Jennifer B. , Cruz Tess Boley
Published: October 2021

This study describes key topics of discussions on Twitter at the intersection of vaping and COVID-19 and documents public reactions to announcements from authoritative health agencies. Twitter posts containing vaping and COVID-19-related terms were collected from 1 December 2019 to 3 May 2020 (n = 23,103 posts). Text classifiers and unsupervised machine learning were used to identify topics in posts. Predominant topics included COVID-19 Respiratory Health (18.87%), COVID-19 Susceptibility (17.53%), Death (10.07%), Other COVID-19 Health Effects (9.62%), and Severity of COVID-19 (7.72%), among others. Public conversations on topics, such as Severity of COVID-19, Transmission, Susceptibility, Health Effects, Death, and Smoking cessation, were shaped by announcements from U.S. and international health agencies. Armed with the insights from this study, medical providers should be prepared to discuss vaping-related health risks with their patients in the era of COVID-19. Misconceptions around vaping as a protective behavior from, and an effective treatment against, COVID-19 should also be corrected.
Correction: Tyson, G.; Wild, J. Post-Traumatic Stress Disorder Symptoms among Journalists Repeatedly Covering COVID-19 News. Int. J. Environ. Res. Public Health 2021, 18, 8536
Authors: Tyson Gabriella , Wild Jennifer
Published: October 2021

In the original article [...]
Effects of Resistance Training Performed with Different Loads in Untrained and Trained Male Adult Individuals on Maximal Strength and Muscle Hypertrophy: A Systematic Review
Authors: Lacio Marcio , Vieira João Guilherme , Trybulski Robert , Campos Yuri , Santana Derick , Filho José Elias , Novaes Jefferson , Vianna Jeferson , Wilk Michal
Published: October 2021

The load in resistance training is considered to be a critical variable for neuromuscular adaptations. Therefore, it is important to assess the effects of applying different loads on the development of maximal strength and muscular hypertrophy. The aim of this study was to systematically review the literature and compare the effects of resistance training that was performed with low loads versus moderate and high loads in untrained and trained healthy adult males on the development of maximal strength and muscle hypertrophy during randomized experimental designs. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (2021) were followed with the eligibility criteria defined according to participants, interventions, comparators, outcomes, and study design (PICOS): (P) healthy males between 18 and 40 years old, (I) interventions performed with low loads, (C) interventions performed with moderate or high loads, (O) development of maximal strength and muscle hypertrophy, and (S) randomized experimental studies with between- or within-subject parallel designs. The literature search strategy was performed in three electronic databases (Embase, PubMed, and Web of Science) on 22 August 2021. Results: Twenty-three studies with a total of 563 participants (80.6% untrained and 19.4% trained) were selected. The studies included both relative and absolute loads. All studies were classified as being moderate-to-high methodological quality, although only two studies had a score higher than six points. The main findings indicated that the load magnitude that was used during resistance training influenced the dynamic strength and isometric strength gains. In general, comparisons between the groups (i.e., low, moderate, and high loads) showed higher gains in 1RM and maximal voluntary isometric contraction when moderate and high loads were used. In contrast, regarding muscle hypertrophy, most studies showed that when resistance training was performed to muscle failure, the load used had less influence on muscle hypertrophy. The current literature shows that gains in maximal strength are more pronounced with high and moderate loads compared to low loads in healthy adult male populations. However, for muscle hypertrophy, studies indicate that a wide spectrum of loads (i.e., 30 to 90% 1RM) may be used for healthy adult male populations.
Mental Health Consequences of the COVID-19 Pandemic Long-Term Exposure in Italian Dermatologists
Authors: Ciuluvica (Neagu) Cristina , Gualdi Giulio , Dal Canton Marco , Fantini Fabrizio , Paradisi Andrea , Sbano Paolo , Simonacci Marco , Dusi Daniele , Vezzoni Gian Marco , D’Acunto Carmine , Lombardo Maurizio , Zanchi Malvina , Alfredo Zucchi , Eisendle Klaus , Prignano Francesca , Amerio Paolo
Published: October 2021

The present study aimed at assessing the consequences of prolonged exposure to COVID-19 distress on mental health in non-frontline health care workers. For this purpose, we have conducted a survey on 425 Italian dermatologists, in the period February–March 2021. The psychopathological symptoms, depression, anxiety, post-traumatic stress symptoms (PTSD), as well as resilience, have been evaluated. The main factors that influence the physician’s psychological health have been also investigated. Our study showed that the physicians older than 40 years, as well as those who lived this period in company, reported more personal resources, better managing the distress. Resilience, COVID-19 beliefs, COVID-19 working difficulties, and age were the common predictors of the severe psychopathological symptoms. An interesting result is that the lower level of resilience was the most powerful predictor of a more severe depression, as well as of a higher severity of generalized anxiety disorder, but not of COVID-19 PTSD. The fear of COVID-19 was the most powerful predictor of COVID-19 PTSD. Home conditions and previous SARS-CoV2 infection constituted significant predictors of severe depressive symptoms, but not of anxiety and COVID-19 PTSD. These results are useful in a better understanding of protective and risk factors involved in COVID-19 long-term distress exposure.
Intersectoral Action for Addressing NCDs through the Food Environment: An Analysis of NCD Framing in Global Policies and Its Relevance for the African Context
Authors: Weimann Amy , Shung-King Maylene , McCreedy Nicole , Tatah Lambed , Mapa-Tassou Clarisse , Muzenda Trish , Govia Ishtar , Were Vincent , Oni Tolu
Published: October 2021

Noncommunicable diseases contribute the greatest to global mortality. Unhealthy diet—a prominent risk factor—is intricately linked to urban built and food environments and requires intersectoral efforts to address. Framings of the noncommunicable disease problem and proposed solutions within global and African regional diet-related policy documents can reveal how amenable the policy landscape is for supporting intersectoral action for health in low-income to middle-income countries. This study applied a document analysis approach to undertake policy analysis on global and African regional policies related to noncommunicable disease and diet. A total of 62 global and 29 African regional policy documents were analysed. Three problem frames relating to noncommunicable disease and diet were identified at the global and regional level, namely evidence-based, development, and socioeconomic frames. Health promotion, intersectoral and multisectoral action, and evidence-based monitoring and assessment underpinned proposed interventions to improve education and awareness, support structural changes, and improve disease surveillance and monitoring. African policies insufficiently considered associations between food security and noncommunicable disease. In order to effectively address the noncommunicable disease burden, a paradigm shift from ‘health for development’ to ‘development for health’ is required across non-health sectors. Noncommunicable disease considerations should be included within African food security agendas, using malnutrition as a possible intermediary concept to motivate intersectoral action to improve access to nutritious food in African low-income to middle-income countries.
Using Virtual Reality (VR) Mock-Ups for Evidence-Based Healthcare Facility Design Decisions
Authors: Shultz Jonas , Jha Rajesh
Published: October 2021

(1) Background: There are many complexities and trade-offs that design teams consider when designing or renovating a built environment for healthcare. Virtual reality (VR) mock-ups can allow design teams to evaluate the planned design. This study aimed to examine the overall value of using VR mock-ups to conduct a simulation-based mock-up evaluation. (2) Methods: Data collected from scenario enactments within a VR mock-up was compared to data collected from an existing medication room with the same design to assess predictive validity. Outcomes regarding quality and patient safety were also examined as a result of design modifications to the VR mock-up which were identified through a post-occupancy evaluation (POE) of the existing medication room. Survey data from participants, hospital design stakeholders, and POE recommendation recipients captured perceptions regarding the evaluation process. Specifically, this included perceptions regarding mock-up and scenario realism as well as utility of the evaluation process. (3) Results: Evidence-based data collected using the VR mock-up accurately assessed workflow (link analysis), bumps, impediments, interruptions, and task completion times. Collecting data pertaining to selection errors and equipment placement were identified after procuring the VR software and therefore the accuracy of these measures was not assessed. Searching behaviours were not possible to capture using the VR software. A 506% return on investment was achieved through the VR mock-up evaluations. (4) Conclusion: Organizations should consider what evaluation objectives are planned and how they will be measured for a mock-up evaluation to determine if VR is appropriate.
Assessment of the Tissue Resident Memory Cells in Lesional Skin of Patients with Psoriasis and in Healthy Skin of Healthy Volunteers
Authors: Kasprowicz-Furmańczyk Marta , Czerwińska Joanna , Placek Waldemar , Owczarczyk-Saczonek Agnieszka
Published: October 2021

Background: In the course of plaque psoriasis, tissue resident memory cells (TRM) are responsible for the phenomenon of “immune memory” of lesions, i.e., the appearance of recurrences of lesions in the same location, as well as Koebner phenomenon. We present results determining the location and amount of TRM in psoriatic lesions in patients suffering from plaque psoriasis, as well as an analysis of the relationship between TRM markers expression and the duration and severity of the disease. Methods: TRM markers (CD4, CD8, CD103, CD69, CD49, CXCR6) and tissue expression of cytokines (IL-17, IL-22) in the lesional psoriatic skin of 32 patients compared with 10 healthy skin samples were evaluated by immunohistochemistry. Results: The presence of TRM markers in both the epidermis and skin with psoriatic eruptions was demonstrated in much higher amounts compared with the skin of healthy volunteers. A significant positive relationship was demonstrated between the expression of TRM markers in patients with plaque psoriasis and the duration of skin lesions. There was no relationship between the amount of TRM and the severity of plaque psoriasis. Conclusions: A thorough understanding of the mechanisms responsible for the development and relapse of plaque psoriasis may contribute to the implementation of more effective therapies.
Online HIV Self-Testing (HIVST) Dissemination by an Australian Community Peer HIV Organisation: A Scalable Way to Increase Access to Testing, Particularly for Suboptimal Testers
Authors: Bell Sara Fiona Elisabeth , Lemoire Jime , Debattista Joseph , Redmond Andrew M. , Driver Glen , Durkin Izriel , Coffey Luke , Warner Melissa , Howard Chris , Williams Owain David , Gilks Charles F. , Dean Judith Ann
Published: October 2021

HIV self-testing (HIVST) introduces opportunities for screening in non-conventional settings, and addresses known testing barriers. This study involved the development and evaluation of a free online HIVST dissemination service hosted by a peer-led, community-based organisation with on-site, peer-facilitated HIV testing, and established referral and support programs for people newly diagnosed with HIV to determine whether this model was feasible and acceptable for engaging MSM, particularly among infrequent and naive HIV-testers, or those living in remote and rural areas. Between December 2016 and April 2018, 927 kits were ordered by 794 individuals, the majority of whom were men who have sex with men (MSM) (62%; 494), having condomless sex (50%; 392), or living outside a major city (38%; 305). Very few (5%; 39) sought the available pre-test peer contact, despite 45% (353) being naive HIV-testers. This study demonstrates that online HIVST dissemination is acceptable and feasible for engaging at-risk suboptimal testers, including those unwilling to test elsewhere (19%; 47/225). With half (50%; 403) unwilling to buy a kit, our study suggests that HIVST will need to be subsidized (cost-neutral to users) to enhance population coverage and access.
Respiratory Monitoring at Bedside in COVID-19 Patients
Authors: Giustivi Davide , Bottazzini Francesco , Belliato Mirko
Published: October 2021

The SARS-CoV-2 (COVID-19) pandemic has forced some reflections to be had surrounding the ventilatory support to be applied to certain types of patients. The model of two phenotypes, set out by Professor Gattinoni and colleagues, suggests that adequate monitoring of respiratory effort may play a key role in the treatment of respiratory failure due to COVID-19. An insufficient control of the patient’s respiratory efforts could lead to an aggravation of lung damage, mainly due to the possibility of generating Patient Self-Inflicted Lung Injury (PSILI) with a consequent aggravation of the pathological picture. Nevertheless, effectively monitoring the patient’s respiratory work, especially in nonintensive settings, is not easy. This article briefly describes some methods that allow the assessment of respiratory effort, such as the use of ultrasound and respiratory tests, which can be performed in nonintensive settings.
Out-of-Hospital Treatment of Hepatitis C Increases Retention in Care among People Who Inject Drugs and Homeless Persons: An Observational Study
Authors: Granozzi Bianca , Guardigni Viola , Badia Lorenzo , Rosselli Del Turco Elena , Zuppiroli Alberto , Tazza Beatrice , Malosso Pietro , Pieralli Stefano , Viale Pierluigi , Verucchi Gabriella
Published: October 2021

Background. People who inject drugs (PWID) and homeless people represent now a large reservoir of Hepatitis C virus (HCV) infection. However, Hepatis C elimination programs can barely reach these subgroups of patients. We aimed to evaluate and compare the retention in care among these difficult-to-treat patients when managed for HCV in hospital or in an out-of-hospital setting. Methods. In our retrospective study, we categorized the included patients (PWID and homeless persons) into two groups according to whether anti-HCV treatment was offered and provided in a hospital or an out-of-hospital setting. We run logistic regressions to evaluate factors associated with retention in care (defined as the completion of direct antiviral agents (DAAs) therapy). Results. We included 56 patients in our study: 27 were in the out-of-hospital group. Overall, 33 patients completed DAAs therapy. A higher rate of retention in care was observed in the out-of-hospital group rather than in-hospital group (p = 0.001). At the univariate analysis, retention in care was associated with the out-of-hospital management (p = 0.002) and with a shorter time between the first visit and the scheduled start of DAAs (p = 0.003). Conclusions. The choice of treatment models that can better adapt to difficult-to-treat populations, such as an out-of-hospital approach, will be important for achieving the eradication of HCV infection.
Applications of 3D Bioprinting in Tissue Engineering and Regenerative Medicine
Authors: Saini Gia , Segaran Nicole , Mayer Joseph , Saini Aman , Albadawi Hassan , Oklu Rahmi
Published: October 2021

Regenerative medicine is an emerging field that centers on the restoration and regeneration of functional components of damaged tissue. Tissue engineering is an application of regenerative medicine and seeks to create functional tissue components and whole organs. Using 3D printing technologies, native tissue mimics can be created utilizing biomaterials and living cells. Recently, regenerative medicine has begun to employ 3D bioprinting methods to create highly specialized tissue models to improve upon conventional tissue engineering methods. Here, we review the use of 3D bioprinting in the advancement of tissue engineering by describing the process of 3D bioprinting and its advantages over other tissue engineering methods. Materials and techniques in bioprinting are also reviewed, in addition to future clinical applications, challenges, and future directions of the field.
Liver Transplantation for Biliary Atresia in Adulthood: Single-Centre Surgical Experience
Authors: Cortes-Cerisuelo Miriam , Boumpoureka Christina , Cassar Noel , Joshi Deepak , Samyn Marianne , Heneghan Michael , Menon Krishna , Prachalias Andreas , Srinivasan Parthi , Jassem Wayel , Vilca-Melendez Hector , Dhawan Anil , Heaton Nigel D.
Published: October 2021

Background: Biliary atresia (BA) is the most common indicator for liver transplant (LT) in children, however, approximately 22% will reach adulthood with their native liver, and of these, half will require transplantation later in life. The aim of this study was to analyse the surgical challenges and outcomes of patients with BA undergoing LT in adulthood. Methods: Patients with BA requiring LT at the age of 16 or older in our unit between 1989 and 2020 were included. Pretransplant, perioperative variables and outcomes were analysed. Pretransplant imaging was reviewed to assess liver appearance, spontaneous visceral portosystemic shunting (SPSS), splenomegaly, splenic artery (SA) size, and aneurysms. Results: Thirty-four patients who underwent LT for BA fulfilled the inclusion criteria, at a median age of 24 years. The main indicators for LT were synthetic failure and recurrent cholangitis. In total, 57.6% had significant enlargement of the SA, 21% had multiple SA aneurysm, and SPSS was present in 72.7% of the patients. Graft and patient survival at 1, 5, and 10 years was 97.1%, 91.2%, 91.2% and 100%, 94%, 94%, respectively Conclusions: Good outcomes after LT for BA in young patients can be achieved with careful donor selection and surgery to minimise the risk of complications. Identification of anatomical variants and shunting are helpful in guiding attitude at the time of transplant.
Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?
Authors: Shimada Eijiro , Endo Makoto , Matsumoto Yoshihiro , Tsuchihashi Kenji , Ito Mamoru , Kusaba Hitoshi , Nabeshima Akira , Nawata Tomoya , Maekawa Akira , Matsunobu Tomoya , Setsu Nokitaka , Fujiwara Toshifumi , Iida Keiichiro , Nakagawa Makoto , Hirose Takeshi , Kanahori Masaya , Oyama Ryunosuke , Isobe Taichi , Ariyama Hiroshi , Kohashi Kenichi , Yamamoto Hidetaka , Oda Yoshinao , Iwamoto Yukihide , Akashi Koichi , Baba Eishi , Nakashima Yasuharu
Published: October 2021

Pazopanib, trabectedin, and eribulin are administered for the treatment of soft tissue sarcomas (STSs); however, there is little consensus on which agent should be preferentially used in a clinical setting. This study assessed whether peripheral immune-related markers served as a useful reference when selecting pazopanib, trabectedin, or eribulin. This study included 63 patients who were administered pazopanib, trabectedin, or eribulin for advanced STSs between March 2015 and December 2020. Patients were divided into three groups based on the first drug administered among these three drugs. Differences in overall survival (OS) or progression-free survival (PFS) among the three groups were analyzed. OS showed no significant differences among the drugs administered first. For patients with low neutrophil-to-lymphocyte ratio (NLR), the OS of patients administered pazopanib as the first choice was shorter than the others (hazard ratio [HR] = 9.53, 95% confidence interval [CI] = 1.94–18.13, p = 0.0018). In the low platelet-to-lymphocyte ratio (PLR) subgroup, the OS of the patients administered eribulin for the first choice was longer than that of the others (HR = 0.32, 95%CI = 0.10–0.98, p = 0.046). Therefore, NLR and PLR might be used as prognostic indicators to dictate whether STS patients receive pazopanib, trabectedin, or eribulin.
Four-Year Temporal Study of an Intertidal Artificial Structure in the English Channel
Authors: Dauvin Jean-Claude , Deloor Maël , Pezy Jean-Philippe , Raoux Aurore , Claquin Pascal , Foveau Aurélie
Published: October 2021

An experimental artificial structure was deployed in March 2014 on the intertidal zone of the Bay of Seine (eastern part of the English Channel), at intervals of one year until April 2018, i.e., from February 2015 onwards, two blocks were collected in April each year. This study provides an inventory of sessile and motile invertebrates living on the artificial hard-bottom and describes the stages of colonization and succession during the four-year study. A total of 84 taxa were identified including 13 sessile and 71 motile taxa. For the sessile fauna, only two taxa Balanus crenatus and Mytilus edulis had colonised the blocks in 2014, and the Taxonomic Richness (TR) was relatively stable during the next three years (between 8 and 10 taxa). The TR of the motile fauna showed an increase between 2014 (5 taxa) and 2015 (34 taxa), and then decreased from 54 taxa in 2017 to 29 taxa in 2018. The abundance of the sessile fauna was very high in 2014 due to the rapid settlement of the barnacle Balanus crenatus, which remained the dominant species throughout the study. Another barnacle Perforatus perforatus, the blue mussel Mytilus edulis and three ascidians including two non-indigenous species Perophora japonica and Corella eumyota, and Molgula sp. were also among the dominant taxa of the sessile fauna. In April 2014, the dominant motile taxa was the decapod Carcinus maenas juvenile, then in 2015 the fauna became dominated by pioneer taxa such as the amphipod of the genus Monocorophium and the tanaid Zeuxo holdichi. A reduction of mean abundance was observed in the last three years of the study, combined with diversification of the dominant species especially those of small size such as Peracarida. The study shows that the colonization of such blocks deployed on oyster tables in the intertidal zone is efficient to test the ability of building material to be colonized in this transition zone.
Mathematical Modelling of Bonded Marine Hoses for Single Point Mooring (SPM) Systems, with Catenary Anchor Leg Mooring (CALM) Buoy Application—A Review
Authors: Amaechi Chiemela Victor , Wang Facheng , Ye Jianqiao
Published: October 2021

The application of mathematical analysis has been an essential tool applied on Catenary Anchor Leg Mooring (CALM) buoys, Wave Energy Converters (WEC), point absorber buoys, and various single point mooring (SPM) systems. This enables having mathematical models for bonded marine hoses on SPM systems with application with CALM buoys, which are obviously a requisite for the techno-economic design and operation of these floating structures. Hose models (HM) and mooring models (MM) are utilized on a variety of applications such as SPARs, Semisubmersibles, WECs and CALM buoys. CALM buoys are an application of SPM systems. The goal of this review is to address the subject of marine hoses from mathematical modeling and operational views. To correctly reproduce the behavior of bonded marine hoses, including nonlinear dynamics, and to study their performance, accurate mathematical models are required. The paper gives an overview of the statics and dynamics of offshore/marine hoses. The reviews on marine hose behavior are conducted based on theoretical, numerical, and experimental investigations. The review also covers challenges encountered in hose installation, connection, and hang-off operations. State-of-the-art, developments and recent innovations in mooring applications for SURP (subsea umbilicals, risers, and pipelines) are presented. Finally, this study details the relevant materials that are utilized in hoses and mooring implementations. Some conclusions and recommendations are presented based on this review.
Acoustic Monitoring of Tidal Flow and Salinity in a Tidal Channel
Authors: Nguyen Hiep Thi , Kawanisi Kiyosi , Sawaf Mohamad Basel Al
Published: October 2021

Fluvial Acoustic Tomography (FAT) is a powerful hydroacoustic system used in the investigations of estuarine dynamics. This research was designed to explore the effectiveness of using a novel and promising method of monitoring the continuous salinity intrusion and velocity distribution in a tidal channel using the FAT scheme. Four FAT units were installed near the riverbanks using a new zigzag system in a rectangular tomographic domain of 700 m × 170 m. The water velocities and salinities measured by FAT in this study were comparable to the data captured by traditional methods, including moving-boat Stream–Pro ADCP, CTD, and CT sensors. It was found that the delays in time between the maximum salinity and high water level along the channel ranged from 12 min to 1.5 h, with these time lags increasing seaward, primarily due to changes in freshwater flows upstream. In addition, the longitudinal salinity gradient was found to decrease toward the mouth of the river, with tide-driven mechanisms most likely being dominant in the dispersion process. The estuary is ebb-dominant, with an asymmetry in the ebb-tide and flood-tide velocities and the highest velocities occurring during the ebb tide. Furthermore, the residual current was found to be affected primarily by the freshwater discharge from upstream.
Examining Pedagogical Translanguaging: A Systematic Review of the Literature
Authors: Prilutskaya Marina
Published: October 2021

In the past two decades translanguaging has proven to be a potent concept in applied linguistics, having generated a large amount of literature that explores theoretical and empirical dimensions of this linguistically inclusive pedagogical approach to language teaching and learning. This systematic literature review focuses on empirical studies that draw on the translanguaging framework in English language teaching (ELT) and beyond. Following PRISMA guidelines for systematic reviews, this study aims to shed light on the current state of knowledge about the affordances of translanguaging pedagogies in a plethora of educational contexts worldwide and to highlight possible avenues for future research. Eleven databases were searched to obtain a dataset spanning from 2011 till February of 2021 and yielding nearly 3000 publications. After duplicate removal, abstract screening, and application of the inclusion/exclusion criteria, a total of 233 studies were coded and analysed to address the research questions. As a result, this systematic review synthesizes the state of knowledge on pedagogical translanguaging, with the aim to inform educators about developments in this rapidly growing field and support researchers in identifying future research priorities on the subject of drawing on learners’ full linguistic repertoires for linguistically inclusive education.
Evaluation of Scopoletin from Penicillium janthinellum Snef1650 for the Control of Heterodera glycines in Soybean
Authors: Yan Jichen , Xing Zhifu , Lei Piao , Sikandar Aatika , Yang Ruowei , Wang Yuanyuan , Zhu Xiaofeng , Liu Xiaoyu , Fan Haiyan , Xuan Yuanhu , Chen Lijie , Duan Yuxi
Published: October 2021

Soybean cyst nematode (SCN) (Heterodera glycines Ichinohe) is responsible for causing a major soybean disease globally. The fungal strain Penicillium janthinellum Snef1650 was evaluated against H. glycines. However, the effective determinants of the P. janthinellum strain are unknown. By performing pot experiments, a functioning compound was isolated from P. janthinellum Snef1650 through organic solvent extraction, semi-preparative HPLC, Sephadex LH-20 column chromatography, and silica gel column chromatography, and the isolated compound was identified to be scopoletin through 1H NMR, 13C NMR, and HPLC–MS. The pot experiments indicated that the treatment of soybean seeds with scopoletin drastically reduced the SCN population. The field experiments performed in 2017 and 2018 revealed that scopoletin decreased over 43.7% juveniles in the roots and over 61.55% cysts in the soil. Scopoletin treatment also promoted soybean growth and improved its yield, with an increase in plot yield by >5.33%. Scopoletin obtained from P. janthinellum Snef1650 could be used as an anti-H. glycines biocontrol agent.
The Exact Solutions of Stochastic Fractional-Space Kuramoto-Sivashinsky Equation by Using (G′G)-Expansion Method
Authors: Mohammed Wael W. , Alesemi Meshari , Albosaily Sahar , Iqbal Naveed , El-Morshedy M.
Published: October 2021

In this paper, we consider the stochastic fractional-space Kuramoto–Sivashinsky equation forced by multiplicative noise. To obtain the exact solutions of the stochastic fractional-space Kuramoto–Sivashinsky equation, we apply the G′G-expansion method. Furthermore, we generalize some previous results that did not use this equation with multiplicative noise and fractional space. Additionally, we show the influence of the stochastic term on the exact solutions of the stochastic fractional-space Kuramoto–Sivashinsky equation.
Tracheitis Caused by Coinfection with Cytomegalovirus and Herpes Simplex Virus
Authors: Lee Yu-Mi , Kim So-Woon , Kwack Won-Gun
Published: October 2021

Clinically significant isolated viral tracheitis is scarce in adults, and upper airway obstruction caused by viral tracheitis is even more infrequent. A 74-year-old woman, who was administered low-dose steroids for two months for chronic obstructive pulmonary disease (COPD), developed dyspnea with stridor and required mechanical ventilation for respiratory failure. Chest computed tomography showed a diffuse tracheal wall thickening with luminal narrowing and peribronchial consolidation in the right upper lobe. Bronchoscopy revealed a proximal tracheal narrowing with multiple ulcerations of the tracheal mucosa surrounded by an erythematous margin. Pathologic examinations of the tracheal mucosal tissue, including immunohistochemistry, revealed a cytomegalovirus (CMV) and herpes simplex virus (HSV) infection. Furthermore, the bronchial alveolar lavage fluid was positive on the CMV real-time polymerase chain reaction. The patient was treated with intravenous ganciclovir for 44 days. The follow-up bronchoscopy 49 days after the initiation of ganciclovir revealed improved multiple ulcerations with scars. We report a rare case of tracheitis caused by coinfection with CMV and HSV in a patient with COPD who had been taking low-dose steroids for months. The case showed that CMV and HSV are potential causes of serious tracheitis and respiratory failure.
Personalised Medicine for Tuberculosis and Non-Tuberculous Mycobacterial Pulmonary Disease
Authors: Kumar Kartik , Kon Onn Min
Published: October 2021

Personalised medicine, in which clinical management is individualised to the genotypic and phenotypic data of patients, offers a promising means by which to enhance outcomes in the management of mycobacterial pulmonary infections. In this review, we provide an overview of how personalised medicine approaches may be utilised to identify patients at risk of developing tuberculosis (TB) or non-tuberculous mycobacterial pulmonary disease (NTM-PD), diagnose these conditions and guide effective treatment strategies. Despite recent technological and therapeutic advances, TB and NTM-PD remain challenging conditions to diagnose and treat. Studies have identified a range of genetic and immune factors that predispose patients to pulmonary mycobacterial infections. Molecular tests such as nucleic acid amplification assays and next generation sequencing provide a rapid means by which to identify mycobacterial isolates and their antibiotic resistance profiles, thus guiding selection of appropriate antimicrobials. Host-directed therapies and therapeutic drug monitoring offer ways of tailoring management to the clinical needs of patients at an individualised level. Biomarkers may hold promise in differentiating between latent and active TB, as well as in predicting mycobacterial disease progression and response to treatment.
A Statistically Based Methodology to Estimate the Probability of Encountering Rock Blocks When Tunneling in Heterogeneous Ground
Authors: Napoli Maria Lia , Barbero Monica , Fontana Roberto
Published: October 2021

Strong rock blocks embedded in a weaker soil matrix are found in many geological units. When tunneling in ground containing cobbles and boulders, extremely challenging conditions can be encountered. Such inconveniences may be avoided by means of appropriate tunneling methods and cutterhead designs, which require the content, frequency, and size of rock blocks to be predicted as accurately as possible. Several approaches have been developed to estimate the block fraction of heterogeneous geomaterials for excavation. However, the estimation of cobble–boulder quantities both all along the tunnel and only partially embedded within the tunnel face remains a critical issue. This study develops a methodology for the estimation of the probability of encountering blocks partially or totally contained within the tunnel excavation area, wherein the area of intersection with the tunnel face is greater than the given critical values. For this purpose, a statistical approach has been implemented in a Matlab routine. The potential of this code is that it provides extremely useful and statistically based information that can be used for making a more rational choice regarding tunneling technique and in terms of designing a suitable cutterhead in order to avoid technical problems during tunnel excavations in heterogeneous ground. The executable code is provided.
Dehydrogenation of Cycloalkanes over N-Doped Carbon-Supported Catalysts: The Effects of Active Component and Molecular Structure of the Substrate
Authors: Wang Jian , Liu He , Fan Shiguang , Wang Shuai , Xu Guanjun , Guo Aijun , Wang Zongxian
Published: October 2021

Efficient dehydrogenation of cycloalkanes under mild conditions is the key to large-scale application of cycloalkanes as a hydrogen storage medium. In this paper, a series of active metals loaded on nitrogen-doped carbon (M/CN, M = Pt, Pd, Ir, Rh, Au, Ru, Ag, Ni, Cu) were prepared to learn the role of active metals in cycloalkane dehydrogenation with cyclohexane as the model reactant. Only Pt/CN, Pd/CN, Rh/CN and Ir/CN can catalyze the dehydrogenation of cyclohexane under the set conditions. Among them, Pt/CN exhibited the best catalytic activity with the TOF value of 269.32 h−1 at 180 °C, followed by Pd/CN, Rh/CN and Ir/CN successively. More importantly, the difference of catalytic activity between these active metals diminishes with the increase in temperature. This implies that there is a thermodynamic effect of cyclohexane dehydrogenation with the synthetic catalysts, which was evidenced by the study on the activation energy. In addition, the effects of molecular structure on cycloalkane dehydrogenation catalyzed by Pt/CN were studied. The results reveal that cycloalkane dehydrogenation activity and hydrogen production rate can be enhanced by optimizing the type, quantity and position of alkyl substituents on cyclohexane.
Niche Differentiation at Multiple Spatial Scales on Large and Small Mediterranean Islands for the Endemic Silene velutina Pourr. ex Loisel. (Caryophyllaceae)
Authors: Murru Valentina , Farris Emmanuele , Santo Andrea , Grillo Oscar , Piazza Carole , Gaio Antonella , Bacchetta Gianluigi , Thompson John D.
Published: October 2021

The aim of this work is to investigate niche variations in endemic Silene velutina (Caryophyllaceae, Angiosperms) on Mediterranean islands that differ in size. Six populations on both large and small islands were sampled across the geographic range of the species. For each population, 10 plots (1 × 2 m, with a 25 cm grill) were randomly placed to quantify environmental (abiotic and biotic factors and disturbance) and population (demographic structure and reproductive success) parameters. Niche parameters related to substrate, plant cover, community diversity and composition and disturbance showed significant variation in relation to island size. At the regional scale, we detected a broader niche on large islands associated with spatial heterogeneity and island size. In contrast, at the local scale, populations on small islands showed a broader niche, potentially due to a release from competition (low diversity and plant cover and absence of phanerophytes). Populations on large islands had a demographic structure biased towards vegetative individuals (seedlings and juveniles) with few reproductive individuals, while those on small islands had a majority of adults. Together, the results on niche breadth and demographic structure concord with the idea of a strategy based on adult persistence on small islands.
Molecular and Morphological Data Improve the Classification of Plantagineae (Lamiales)
Authors: Shipunov Alexey , Fernández-Alonso José Luis , Hassemer Gustavo , Alp Sean , Lee Hye Ji , Pay Kyle
Published: October 2021

The tribe Plantagineae (Lamiales) is a group of plants with worldwide distribution, notorious for its complicated taxonomy and still unresolved natural history. We describe the result of a broadly sampled phylogenetic study of tribe. The expanded sampling dataset is based on the trnL-F spacer, rbcL, and ITS2 markers across all three included genera (Aragoa, Littorella and Plantago) and makes this the most comprehensive study to date. The other dataset uses five markers and provides remarkably good resolution throughout the tree, including support for all of the major clades. In addition to the molecular phylogeny, a morphology database of 114 binary characters was assembled to provide comparison with the molecular phylogeny and to develop a means to assign species not sampled in the molecular analysis to their most closely related species that were sampled. Based on the molecular phylogeny and the assignment algorithm to place unsampled species, a key to sections is presented, and a revised classification of the tribe is provided. We also include the description of new species from North America.
Special Issue: The Application of Microorganisms in Wastewater Treatment
Authors: Kushkevych Ivan
Published: October 2021

Today, water is an integral part of the course of our lives, from the operation and maintenance of households to extensive industrial and agricultural use [...]
Multispecies Q Fever Outbreak in a Mixed Dairy Goat and Cattle Farm Based on a New Bovine-Associated Genotype of Coxiella burnetii
Authors: Bauer Benjamin U. , Knittler Michael R. , Herms T. Louise , Frangoulidis Dimitrios , Matthiesen Svea , Tappe Dennis , Runge Martin , Ganter Martin
Published: October 2021

A Q fever outbreak on a dairy goat and cattle farm was investigated with regard to the One Health concept. Serum samples and vaginal swabs from goats with different reproductive statuses were collected. Cows, cats, and a dog were investigated with the same sample matrix. The farmer’s family was examined by serum samples. Ruminant sera were analyzed with two phase-specific enzyme-linked immunoassays (ELISAs). Dominant immunoglobulin G (IgG) phase II levels reflected current infections in goats. The cows had high IgG phase I and II levels indicating ongoing infections. Feline, canine, and human sera tested positive by indirect fluorescent antibody test (IFAT). Animal vaginal swabs were analyzed by qPCR to detect C. burnetii, and almost all tested positive. A new cattle-associated C. burnetii genotype C16 was identified by the Multiple-Locus Variable-number tandem repeat Analysis (MLVA/VNTR) from ruminant samples. Additionally, a possible influence of 17ß-estradiol on C. burnetii antibody response was evaluated in goat sera. Goats in early/mid-pregnancy had significantly lower levels of phase-specific IgGs and 17ß-estradiol than goats in late pregnancy. We conclude that the cattle herd may have transmitted C. burnetii to the pregnant goat herd, resulting in a Q fever outbreak with one acute human case. The influence of placentation and maternal pregnancy hormones during pregnancy on the immune response is discussed.
Turismo en ecosistemas de manglar: un potencial turístico como alternativa de desarrollo en el Recinto Nuevo Porvenir
Authors: Asuncion Genesis , Martinez Cecilia
Published: October 2021

Ecuador posee 161.835 hectáreas de manglar, de las cuales 72.523 son áreas protegidas y 68.000 permanecen en  algunos medios de conservación. Durante años los  ecosistemas han sido sujetos a efectos negativos  como la tala indiscriminada, la deforestación  de árboles, la  acuicultura, los cambios climáticos, pérdida de la biodiversidad, desaparición de muchas especies, el empobrecimiento de las comunidades,  entre otros, son  factores que están ocasionando su deterioro y  desaparición. El ecoturismo promueve la inversión, la demanda turística generará dinamismo en la economía, restructuración social de las comunidades locales mediante  la implementación  y desarrollo de proyectos que  ayuden a la conservación de los ecosistemas y los servicios que ofrecen, a la creación de fuentes de trabajo sin dejar de lado la incorporación de experiencias  y asesoramiento de otros países, que con la ayuda de empresas nacionales y privadas permitirán  ofrecer productos turísticos coherentes a la realidad actual de la  preservación y conservación medio ambiental, los cuales permitirán dar a conocer a Ecuador su gente, su cultura ,su tierra.

Esta fue una investigación de campo de tipo descriptiva,  se utilizó la entrevista como una herramienta para obtener respuestas sobre el objetivo de estudio, dando como resultado que en el Recinto Nuevo Porvenir del Cantón Naranjal, el ecoturismo se presenta como una alternativa en el ecosistema de los manglares que contribuirán a la conservación del mismo, con emprendimientos posibles  y de resultados visibles permitiendo la unión del turismo con la naturaleza, pero por sobre todas las cosas lograr disminuir la pobreza y preservar los recursos naturales.