bluuebunny/crossref_metadata_2025 huggingface dataset:
Образы современности в XXI веке: космодернизм
Authors: Афанасов Николай Борисович , Павлов Александр Владимирович
Published: July 2019

В статье рассматривается одна из последних попыток «переписывания» постмодернизма, предпринятая американским философом Кристианом Морару, известная под названием «космодернизм». Воссоздан ход дискуссии о необходимости построения нового философского проекта взамен постмодернизму Фредрика Джеймисона, на которую опирался в своей философской работе Морару. Статья предлагает историко-философскую реконструкцию становления теории космодернизма в ее связи со спорами вокруг постпостмодернизмов начала XXI в. Также текст вносит ясность в вопрос соотношения концепций «космодернизма» и «планетаризма», являющихся историческими наименованиями одного проекта.

Критическое рассмотрение концепции космодернизма/планетаризма описывает методологию работы Морару, состоящую в анализе литературных произведений с середины XIX в. до наших дней. Именно они демонстрируют, по мнению философа, наиболее репрезентативные черты современности. В рамках анализа теории и ее сопоставления с конкурирующими социально-философскими проектами (диджимодернизм и метамодернизм) выделяются наиболее интересные для актуальной социальной философии стороны космодернизма: указание на размывание субъект-объектных границ в современности, анализ феномена нетовизации пространств и объектов, переосмысление характера завершающейся глобализации, перспективы омирщвления дискретного мира до культурного концепта планеты. Слабой стороной философской работы Морару является концентрация исключительно на авангардной литературе, что ограничивает автора в возможности работы с эмпирическим материалом современности, и ослабляет позиции его теории в сравнении с другими проектами.
Элитаристский дискурс справедливости: современные концепции и Россия
Authors: Канарш Григорий Юрьевич
Published: July 2019

В статье на примере концепций двух влиятельных авторов второй половины XX в. — социологов Майкла Янга и Дэниела Белла — анализируется идея меритократии — власти наиболее достойных, наиболее заслуженных.

Рассматриваются основные идеи знаменитой книги (антиутопии) М. Янга «Возвышение меритократии». Охарактеризованы основные этапы становления меритократического общества в антиутопии Янга. Показано, что основная проблема меритократии в изображении британского социолога — ее морально-этические изъяны, которые приводят в результате к классовому конфликту и последующему кризису и падению меритократии. С точки зрения автора статьи, более привлекательным выглядит социальный идеал, обрисованный Янгом, в рамках которого «общество талантов» понимается не как сугубо технократическое, а как подлинное общество равных возможностей.

Показано, что Д. Белл считает меритократию неотъемлемым атрибутом постиндустриального общества, однако учитывает критику этой идеи в работах М. Янга и Д. Ролза. Поэтому подлинная меритократия у Белла — это «справедливая меритократия», сочетающая равное уважение всех с отличием некоторых (наиболее достойных).

Изучены взгляды на проблему меритократии в современной России. Автор опирается главным образом на анализ российской ситуации у отечественного элитолога Г. К. Ашина. Он показывает, что элитные трансформации в постсоветской России, значительно изменив некоторые важные характеристики элиты, не изменили главного — ее морального облика.

В заключение автор указывает, что меритократия обязательно должна сочетаться с развитыми демократическими механизмами, для того чтобы избежать отчуждения народа от власти.
Дискуссионные вопросы феномена Нового времени в зеркале современности
Authors: Антипов Антон Александрович
Published: July 2019

Статья посвящена феномену Нового времени и его влиянию на формирование и пути разрешения проблем современного мира.  В работе рассмотрены мировоззренческие, психологические и социально-политические истоки модерна и показано, что опосредованное влияние Античности, принципиально новый формат науки-силы и философии деятельного рационального субъекта, социально-политические процессы между государством и обществом, героизм и мещанство в совокупности стали теми ключевыми факторам, которые привели к формированию буржуазной капиталистической эпохи.

Основными антиномиями, которые рождает нововременной дискурс, являются антиномии о наличии/отсутствии капиталистического духа, ценности рационализма и влиянии глобализации на культуру. Анализ антиномий показал, что утверждение наличия капиталистического духа является умозрительным и необходимо говорить о социально-исторических, политических условиях, которые сформировали определенные поведенческие реакции.

В заключении подчеркивается, что модерн изменил не сущность человека, а средства и условия человеческого бытия, конструкцию реальности, вытеснил созерцательное и установил потребительское отношение человека к миру, поставив при этом вопрос о будущем культуры и человека в условиях сконструированной им «второй природы».
Role of the plant heterotrimeric G-proteins in the signal pathways regulation
Authors: Bovin Andrey D. , Dolgikh Elena A.
Published: July 2019

Animal and fungal heterotrimeric G-proteins are among the well-known regulators of signaling pathways. Plant studies have shown that G-proteins may also be involved in the regulation of many processes. G-proteins are involved in hormonal regulation, control of cell proliferation, response to abiotic factors, control of biotic interactions and many others. It turned out that with a smaller variety of subunits, G-proteins of plants can have a greater variety of mechanisms for activating and transmitting signals. However, for most processes in plants the mechanisms of operation of heterotrimeric G-proteins remain poorly understood. This review is devoted to the analysis of modern ideas about the structure and functioning of heterotrimeric plant G proteins.
Protective effect of extracts of Teucrium Polium and Rumex Crispus against cyclophosphamide-induced genotoxic damage in human lymphocytes
Authors: Yuksel Sengul , Sezer Selcen Korkmaz , Kurtoglu Elcin Latife , Bag Harika Gozukara
Published: July 2019

Teucrium polium (T. polium) and Rumex crispus (R. crispus) are plant species that grow widely in Anatolia and are thought to have healing effects for many diseases. In this study plant extracts are suggested as alternative agents in repairing cellular damage by using sister chromatid exchange (SCE), micronucleus (MN), mitotic index (MI), replication index (RI) and nuclear abnormalities (NAs), against the genotoxicity of cyclophosphamide (CP) in the human lymphocyte cells. 8 experimental groups were formed in the study. The cell culture medium was supplemented with 0.16 g/ml CP and the cells were treated with 50, 100 and 250 M T. polium and R. crispus extracts in the presence and absence of CP. As a result, CP significantly decreased MI frequency while increasing SCE, MN and NAs frequencies in cells. 100 M T. polium plus CP decreased SCEs when compared with CP alone. In addition, MN frequency was significantly decreased in 100 M T. poliumplus CP and 250 M R. crispus plus CP combine groups. Our results suggest that these plant extracts are not genetically damaging and have improving effects at these doses.
Historia médica: su potencialidad en la gestión de costos hospitalarios
Authors: Vargas González Vilma Estela , Hernández Carmen Chiquinquirá
Published: July 2019

Objetivo: Identificar las potencialidades de la historia médica, como fuente de suministro de datos necesarios, para la obtención de información de costos; información de valiosa importancia para la gestión hospitalaria. Metodología: En lo referente al diseño es una investigación de fuente mixta: Investigación de campo y documental, con alcance descriptivo. Se utilizó como técnica para la realización de la investigación la entrevista y cómo instrumento la guía de entrevista. Además se realizó revisión documental y articulación de teoría con evidencia empírica. Resultados: Se encontró que la historia médica o expediente sanitario contiene, entre otros aspectos, la relación de los actos y procedimientos médicos realizados durante la estancia de un paciente en el centro hospitalario, actos y procedimientos médicos susceptibles de generar costos. Entre las potencialidades de la historia médica se encuentra que ésta es una herramienta que permite el conocimiento de elementos de costos generados en la atención de los pacientes; en tal sentido, la historia médica se vincula al sistema de información, siendo útil para la gestión hospitalaria y el control de los costos. Conclusiones: Se concluye que la historia médica genera datos susceptibles de alimentar el sistema de información para la gestión de costos hospitalarios, en aras de suministrar servicios de calidad a los pacientes y optimización de la gestión.
Um diagnóstico sobre a adoção de sistemas de informação nas atividades dos artesãos da Paraíba
Authors: Ariete Izabele Cristina Linhares de , Santana Adriana Moura Beserra de , Lima Madony Araújo , Silva Viviane Rodrigues da , Medeiros Ramon Leonn Victor
Published: July 2019

The Information Systems have great importance to support the processes of any business, establishing control in the operations and aiding in the decision making. Within this scope, this study aims to contribute with the assumption that the craftman entrepreneur should use information systems to have more control over his activities. Thus, the objective is to diagnose the knowledge about information systems in the professional reality of the craftman entrepreneurs of the state of Paraíba. As for the methodological strategy, questionnaires were applied to craftman who were present at the XXIII Craft Fair of Paraíba. The research made it possible to verify that most artisans do not have the qualification to use digital media, a digital education is required, it is also essential to provide means for access to information and tools that assist in the management of projects, even if in a simplified way , improving thus, the performance of the daily activities of these artisans.
Evaluation of Chronic Subdural Hematoma Volume Calculated via Cavalieri’s Principle
Authors: KARAKAYA Zeynep , SARİTAS Ayhan , YESİM AKYOL Pınar , ESAD TOPAL Fatih , PAYZA Umut , BİLGİN Serkan
Published: July 2019

Background: Chronic subdural hematoma (CSDH) is a frequently encountered entity in
neurosurgery. The
objective of this study was to describe the use of unbiased Cavalieri principle
to assess CSDH volume to total brain volume fraction (Percentage) and compare it with the clinical features of
the patients.

Methods: A total of
33 patients were included in the study. Computed tomography (CT) was acquired
from the hospital-imaging database. The ratio of hematoma volume, brain volume, and hematoma volume to
brain volume were measured via CT by two clinicians. Measurements
were compared with clinical findings.

Results: The sample consisted of 22 males and
11 females and mean age 67,27±12,63 years. The measured
hematoma volume was 89,78 ± 54,13 cm3, the brain volume was 1329,91
± 2098,35 cm3 and the percentage volume was 8,14 ± 4,92 cm3.
The brain volume values of the cases with impaired consciousness were found to
be statistically significant (p <0.05).

Conclusion: It should be kept in mind
that the bleeding volume of patients with vomiting may be higher.
DEVELOPMENT OF A METHOD TO EVALUATE THE EFFICIENCY OF NANOSCALE ZERO-VALENT IRON (NZVI) TO DEGRADE POLLUTANTS
Authors: Ferrari Giovana Arrighi , Cruz Felipe Santana de Oliveira , Moreira Renata Pereira Lopes , Puiatti Gustavo Alves , Moraes Luiza Dumont de Miranda , Oliveira André Fernando
Published: July 2019

Iron nanoparticles (nZVI) stand out in environmental remediation due to their high reactivity. However, they have low chemical stability when exposed to oxygen and water, reducing their effectiveness. The objective of this work was to develop and validate a method to evaluate the efficiency of nZVI from synthetic lots L01 and L02, from the degradation of dyes, orange and methyl violet (MO and MV). The previous degradation tests provided the best results for MO (~100% degradation, 12 min reaction, 0.5 g L-1 dose). The optimization using Factorial Planning obtained the optimal condition, CMO = 5.98 mol L-1 and DnZVI = 0.56 g L-1. The Boltzmann model fitted the results obtained (R2 = 0.993). Finally, a mathematical relationship was obtained that provided equivalent doses of L01 and L02 in relation to the Standard. The applied mathematical adjustments presented R²> 0.99 and errors <4%.
Açai (Euterpe oleracea, Mart.), an Amazonian fruit has antitumor effects on prostate cancer cells
Authors: Jobim Micheli Lamberti , Barbisan Fernanda , Fortuna Milena , Teixeira Cibele Ferreira , Boligon Aline Augusti , Ribeiro Euler Esteves , Cruz Ivana Beatrice Mânica da
Published: July 2019

Açai (Euterpe oleracea, Mart.) is fruit broadly consumed in the world. From its chemical matrix is possible that açai could has some cytotoxic effect against prostate cancer (PCa). To test this hypothesis using an in vitro PCa model DU145 cell. Additionally, potential synergism between açai and docetaxel (DO), a chemotherapic drug used to treat advanced PCa was also evaluated. Cells were exposed an açai hydro alcoholic extract at different concentrations (1 to 1000 μg/mL) and its effect on viability, apoptosis and cellular proliferation was determined by MTT assay, growth cell, clonogenic assays and cell cycle analysis by flow cytometry. Differential modulation of Bcl-2 and BAX genes was also determined by Pcr quantitative in real time (qRT-PCR) analysis. Açai at lower concentrations (1-10 μg/mL) presented significant cytotoxic and antiproliferative action against PCa cells decreasing frequency of S phase cycle. Probably, this effect was associated with its strong down-regulation of Bcl-2 gene. However, açai did not contribute to improve Docetaxel effect´s on PCa cells. Açai’s PCa antitumor effects could be related to elevate concentrations of orientin plus vitexin, p-coumaric acid, apigenin and catechins present its chemical matrix, which are molecules with antitumor effect previously described in the literature.
Properties of chitosan matrix composites with hydroxyapatite and carbon nanotubes, and their use in bone tissue engineering
Authors: Correia João Victor Freitas Barros , Correia Matheus Freitas Barros
Published: July 2019

There is a growing demand for bone grafts by various clinical sectors, such as aesthetic procedures, treatment of injuries and dentistry, the use of synthetic materials is shown to be good due to the availability and the reduction of risks that their use brings, among the materials that are used in the clinic can be cited the chitosan matrix composites (CHI) with hydroxyapatite (HA) and carbon nanotubes (CNTs), which uses materials that are already used in the clinic HA and CHI with an innovative material in the sector the CNTs. The aim was to analyze and compare data from the current state of the art of CHI matrix composites with HA and CNTs applied in bone tissue engineering. This study is based on a review of the specialized literature on articles in online scientific journals, with thematic issues related to the properties of the biocomposite on board. The influence of the use on the composite properties generated by the use of CNTs together with the HA in the CHI matrix, for biomedical applications, more specifically in bone tissue engineering, was observed. It was observed that with subtle increases of CNTs in the CH composite Ha composites, the bioactivity, osteoconduction, antibacterial activity, mechanical properties of the composites, changes in the nanotexturas, and a homogeneous distribution of the materials occur, potentiality of its use in more than one application within bone tissue engineering. In the present study it was possible to observe that CHI matrix composites with HA and CNTs present a combination of properties highlighting the potential for application in bone tissue engineering.
Evaluation in vitro of antimicrobial activity of tucumã oil (Astrocaryum Vulgare)
Authors: Rossato Aline , Silveira Larissa da Silva , Lopes Leonardo Quintana Soares , Filho Walter Paixão De Sousa , Schaffer Larissa Finger , Santos Roberto Christ Viana , Sagrillo Michele Rorato
Published: July 2019

Hospital Infection is a major health problem and affects around 1.5 million people annually around the world. The Amazon region has a wide diversity of native palm trees that have fruits and oilseeds. Astrocaryum vulgare, commonly known as Tucumã in Brazil, belongs to the family Arecaceae. This palm has orange, fleshy, single-egg-shaped fruits that are used for therapeutic purposes in diseases of the eyes and skin due to the high content of carotenoids, oil is used in cooking, health treatment and massage. This study evaluated the antimicrobial activity of the Tucumã oil against 18 microorganisms. The antimicrobial activity of Tucumã was measured through the determination of the Minimum Inhibitory Concentration (MIC), as well as the determination of the Minimum Microbicidal Concentration (CMM) aiming to contribute to the discovery of new antimicrobials against pathogenic microorganisms’ human health and may contribute to the treatment of nosocomial infections. The results showed that the oil of Tucumã presented antimicrobial activity against five important bacteria, four Gram - positive bacteria (Enterococcus faecalis, Enterococcus faecium, Staphylococcus epidermidis and Streptococcus agalactiae) and one Gram - negative (Acinetobacter baumannii).
Porquê ser Editor-Chefe de uma Revista Científica Médica?
Authors: Guerra Miguel
Published: July 2019

N/a.
Implementation of Relating, Experiencing, Applying, Cooperating, Transferring (REACT) Model to Students Learning Achievement in Chemical Basic Law Material at 10th Grade Students of SMA Negeri 1 Kalasan
Authors: Cahyaningrum Ristanti , Febriana Beta Wulan
Published: July 2019

This study aimed to determine the significant differences of  learning achievement at 10th grade students of SMA Negeri 1 Kalasan between the application of conventional learning models with learning models Relating, Experiencing, Applying, Cooperating, Transferring (REACT) in the domain of knowledge, attitudes, and skill  on the Basic Chemical Law materials. This study also aimed to know students’ response to learning using REACT model. This research was an experimental using Quasi Experimental Design, namely Posttest Only with Nonequivalent Groups Design. The population in this study was all students of 10th grade SMA 1 Kalasan in the academic year 2017/2018. This study used two classes as the study sample. The data were analyzed using Independent Samples T-Test parametric test for the knowledge and attitude domain, and Mann Whitney U non parametric test for the skill domain. The results of this study can be concluded that (1) there was  no significant difference in student learning achievement in the  knowledge domain, (2) there was  no significant difference in student learning achievement in the attitude domain, and (3) there was  significant differences in student learning achievement in the skill domain  between the application of conventional learning models with REACT learning models in the  Chemical Basic Law and (4) students gave a good response to the REACT learning model performed.
Bismuth-containing glassy reference materials for establishing the content of transition elements using luminescent-based methods
Authors: Borisova V. V. , Kutvitsky V. A. , Mironova E. V. , Romanova I. A. , Ostanina O. I.
Published: July 2019

Modern express methods of analytical control are widely used for monitoring the quality of oxide materials. However, the possibilities of these methods are currently limited by the lack of versatile homogeneous reference materials (RMs). Such RMs can be produced most effectively by vitrification methods. In this connection, glassy RMs based on bismuthborate systems are of great interest. In the earlier research, bismuth-borate RMs were used for comparison purposes in determining the composition of complex oxide systems using the X-ray fluorescence method. This work considers issues associated with the synthesis and application of bismuth-borate glassy RMs for determining the content of transition elements in oxide compounds and mixtures using luminescence analysis. Luminescence analysis was used as a research method due to its high selectivity and low detection limits with respect to elemental impurities in controlled objects (usually constituting 1 · 10–6–1 · 10–4 wt %). Bismuth-borate glassy RMs are shown to be capable of luminescence under UV radiation in the visible range at the temperature of 77 K. It is established that the introduction of the oxides of transition and rare earth elements (REE) into the RM composition leads to the quenching of the exciton emission band in the glasses studied at 77 K, as well as to the appearance of bands typical of REE ion radiation both at 77 K and at 298 K. Glassy RMs doped with transitionelement oxides are found to quench the luminescence of both bismuth and REE ions at the temperature of 77 K. On the basis of the results obtained, procedures for determining the content of quenching elements in oxide materials have been developed. The metrological characteristics of these procedures have been evaluated.
Application of Raman spectroscopy in the quality control of injectable medicines
Authors: Krasheninina M. P. , Medvedevskikh M. Yu. , Galeeva E. V. , Galeev R. R.
Published: July 2019

This paper presents the results of the identification procedure certification and subsequent quantitative determination of the active ingredients of two-component injectable medicines (active ingredient and solvent) using Raman spectroscopy. The main objective of the research was to select approaches for estimating the metrological characteristics of the measurement procedure, which include consideration of the methodological parameters and provide the metrological traceability of measurement results to SI units. According to this purpose, the GVET 176‑1‑2010 State Secondary Measurement Standard for units of mass fraction, mass (molar) concentration of components in solid and liquid substances and materials based on volumetric titration was used. The following substances were chosen as the research objects for estimating the metrological characteristics of the measurement procedure: ascorbic acid, novocaine and sodium thiosulphate. The authors of the work have demonstrated the measurement-procedure certification results, whose accurate determination was confirmed by the results of interlaboratory comparisons. The obtained results confirmed the accuracy of the identification procedure and subsequent quantitative determination, which proves its applicability for the determination of the active ingredients in two-component injectable medicines. In addition, the possibility of developing reference materials based on the medicines under study is indicated. Further development of this study may be directed at the development of an identification procedure and its certification, with subsequent quantitative determination of the active ingredients of injectable medicines having three components as well as those having a more complex composition.
Relationships between Urine Albumin Excretion and Dietary Habits in Patients with Type 2 Diabetes
Authors: Matsui Sadako , Someya Yasuhisa , Yoshida Hiroshi
Published: July 2019

Background: The dietary factors and nutrients contributing to the prevention of microalbuminuria in type 2 diabetic nephropathy is unclear, so we investigated dietary factors affecting urinary albumin excretion in patients with type 2 diabetes. Methods: 42 patients with type 2 diabetes were participated, the subjects were divided to a normal albuminuria group (urinary albumin / creatinine ratio of less than 30 mg / g Cr) and a microalbuminuria group of 30 mg / g to 299 mg / g Cr. We performed casual blood sampling and conducted a food frequency questionnaire survey. Results: There were no significant differences in age, BMI and other physiological and biochemical data, the average daily intake of energy and many of nutrients, while β-cryptoxanthin was significantly lower in the microalbuminuria group than in the normal group (506.4 ± 793.9 μg/day vs. 715.3 ± 500.3 μg/day, p <0.05). The intake of 17 food groups per day showed that the intakes of fruits were significantly lower in the microalbuminuria group than in the normal group (76.9 ± 134.1 g vs. 111.9 ± 84.5 g, p <0.05). Conclusion: These results suggest that fruits and foods rich in β-cryptoxanthin would make it possible to prevent diabetic nephropathy progression.
Mutations in Conserved Regions of Eel Luteinizing Hormone Receptor Result in Constitutive Activation or Inactivation
Authors: Byambaragchaa Munkhzaya , Kim Dong-An , Kim Dae-Jung , Hong Sun-Mee , Kang Myung-Hwa , Min Kwan-Sik
Published: July 2019

Luteinizing hormone receptor (LHR) is a member of the seven-transmembrane (TM) receptor family. Several mutations in LHR have been identified in many mammalian species, leading to either constitutive activation or inactivation of the receptor. Mutations in highly conserved regions of the TM domain have been reported. In this study, we analyzed signal transduction by three constitutively active mutants (designated M410T, L469R, and D590Y) and two inactivating mutants (D383N and Y546F) of eelLHR known as naturally occurring in human LHR . To directly assess the functional effects of these mutations, site-directed mutant receptors were transiently expressed in CHO-K1 cells and cAMP accumulation stimulated by recombinant eelLH (rec-eelLH) was measured by homogeneous time-resolved fluorescence (HTRF) assays. The cAMP response in cells expressing eelLHR wild-type (eLHR-WT) increased in a dose-dependent manner with rec-eelLH ligand stimulation. Cells expressing the activating eelLHR mutants, M410T, L469R, and D590Y, exhibited a 4.0-, 19.1-, and 7.8-fold increase in basal cAMP response, respectively. However, their maximal responses were approximately 73, 53, and 92%, respectively, of the maximal response of LHR-WT. The L469R mutant exhibited a particularly marked increase in cAMP production in the absence of agonist. The maximal responses of the inactivating mutants, D383N and Y546F, were 32 and 24% of LHR-WT, respectively. However, the inactivating mutations did not completely impair signal transduction. Thus, we report here the first characterization of activating and inactivating mutations in eelLHR and we show that these mutations have similar effects as those reported for mammalian LHRs. Moreover, eelLHR with activating mutations showed constitutive cAMP responses. These results provide important data on the signal transduction of constitutively active and inactive LHR mutants. Further studies should aim to identify the mechanism responsible for the significant increase in basal cAMP response in the constitutively activated eelLHR mutants.
PROTECCIÓN DEL PATRIMONIO TURÍSTICO MEDIO AMBIENTAL EN CHILE. SISTEMA VIGENTE Y PRINCIPALES FALENCIAS A SUPERAR
Authors: ÁLVAREZ ARAVENA ALEJANDRO , OLIVARES RAMÍREZ MAXIMILIANO
Published: July 2019

Este trabajo tiene por objetivo dar cuenta de los principales instrumentos contenidos en la legislación chilena para proteger el patrimonio turístico, revisando las sanciones que se imponen ante la infracción de las obligaciones que pesan sobre los turistas. Junto con ello y a raíz de casos emblemáticos que han afectado al país, se pretende determinar la forma en que la legislación debe adaptarse para afrontar los desafíos que una actividad en crecimiento plantea a nuestro entorno.
Gambaran Mengenai Metode Mengajar Sesuai dan Tidak Sesuai Dikembangkan dalam Program TK
Authors: Yenny Yenny
Published: July 2019

With the increasing understanding of how young children develop and learn, there has been a greater emphasis on the education of young children. This study aims to obtain a description of appropriate and inappropriate teaching methods developed in a kindergarten program, specifically in the village of South Meruya. This research is qualitative descriptive, using interview method to teaching method of kindergarten teacher. The subjects consisted of 8 kindergarten teachers, consisting of 4 teachers of kindergarten and 4 teachers of kindergarten. The results obtained from this research are the kindergarten teachers in Meruya Selatan Village have shown appropriate teaching methods developed in the kindergarten program almost on all components except the teaching strategy component (addressing the ideas conveyed by the children), content and curriculum approach (aesthetic expression), reciprocal relationship with parents, and program policies (teacher-child ratio). 
Pengaruh Aktivitas Membuat Boneka Jerami Terhadap Perkembangan Kreativitas dan Sosial Emosional Anak Kelompok B di TK Muslimat NU 02 dan TK PGRI 01 Kabupaten Lumajang
Authors: Agustin Laili Devi
Published: July 2019

The results of the initial observations indicate that the interaction and creativity of children Group B is still low. In fact, children should be encouraged to develop an interest in learning everything. Therefore, the researchers examined the effect of treatment on Effect of Straw Puppet Making Activity Against Creativity and Social Emotional Development of Children in Kindergarten Group B Muslimat NU 02 and TK PGRI 01 Lumajang.formulation of the problem of this study is whether the activity of making straw dolls affect the social emotional development of children's creativity and group B. This study aimed to determine the effect of the activity of making straw dolls influential the social emotional development of children's creativity and group B
Peningkatan Perilaku Prososial pada Anak Usia 4-5 Tahun Melalui Kegiatan Outbond Fun Estafet di Tk PGRI Langkap Burneh Bangkalan
Authors: Mayangsari Dewi , Sari Evi Dwi Novita , Munaila Nofiana
Published: July 2019

Prosocial behavior is an important value in developing social relationships with the community environment starting with learning to adjust and cooperate in play activities. In Kindergarten PGRI Langkap, Burneh Bangkalan parents and teachers complain about the child's prosocial behavior is perceived as lacking. One strategy chosen to develop this aspect is to invite children to play outside the room, held a competition and usually called Outbond. Outbond activities in this research called Fun Outbond Esafet implemented in groups. The purpose of this study is the researchers wanted to know the effectiveness of activities Outbound Fun Relay in Kindergarten PGRI Langkap Burneh Bangkalan to improve prosocial behavior. The methods used Classroom Action Research. The results of this research, Outbound Fun Relay activities can improve the prosocial ability of children aged 4-5 years in Kindergarten PGRI Langkap, Burneh Bangkalan. The child's prosocial ability increased from 31% to 86.20% over two cycles.
Profil Kemampuan Matematika Anak Usia Dini Melalui Learning to Think Different
Authors: Nisa' Titin Faridatun , Karim Muhammad Busyro
Published: July 2019

This study aims to determine the profile of early childhood math skills in learning to think different. The type of this research is explorative research with qualitative approach. This research results will be analyzed by using qualitative analysis. The results showed that the profile picture of early childhood math ability in the group of children with below average ability had similarities with the average group in logical and symbolic thinking ability with the categories evolving as expected. As for the ability to think critically the same, that category began to grow. A group of children with below average skills has problem-solving skills with the category beginning to develop, while the group of children with average ability including the category evolves according to expectations.
Peningkatan Kecerdasan Interpersonal Melalui Permainan Tradisional pada Anak Kelompok B
Authors: Widayati Widayati
Published: July 2019

This study aims to improve early childhood entrapersonal intelligence through traditional games. This reseach was do in TK Mardi Putra 03 Desa Sumber Brantas, Kota Batu-Malang. This research used actiob reseacrh. Data analysis used Kurt Lewin design. The result of the research shows was childrens’s intrapersonal intelligencesthrough traditional games could increasi of grade B oinderganten. The end of result of the overall analysis data was the precentage increase wich showed from pre-intervency class average is 38,9% up to 82,13% at posttest result.
Pengaruh Kegiatan Herbarium Terhadap Perkembangan Kreativitas Anak di PAUD Kasih Ibu I Luar Parit
Authors: Ranti Endang Susri , Hazizah Nur
Published: July 2019

The purpose of this study was to determine the creativity development of children 5-6 years old with herbarium activities in PAUD Kasih Ibu I Luar Parit. The creativity development activities in the field use dry leaf collage activities and serveral other activities such as drawing coloring, and forming fruits from plasticine. But the work produced is almost exactly the same as the teacher’s example. Through this herbarium activity researhers want to see the creativity development of children 5-6 years. Quantitative reasearch with experimental methods in the form of quasi experimental is a method in this study. All children in PAUD Kasih Ibu I Luar Parit totaling 34. Group B1 experimental sample and B2 control sample with 12 children each class. Purposive sampling. As for the technique of collecting data using deed test and oral test.statement instrumen grid is used as a data collection tool. The results of the average experimental 77,77 and the control 70,83. So the use of herbarium activities had a significant effect on the development of creativity of children 5-6 years old at the PAUD Kasih Ibu I Luar Parit academic years 2018/2019.
Kelekatan Anak dengan Pengasuh Tempat Penitipan Anak
Authors: Puspita Heni
Published: July 2019

This article aims to describe the relationship between a child who is cared for in a Child Care Center and a caregiver. This study used a qualitative approach with phenomenological research methods with the subjects of the study as many as 2 caregivers in the Yasmin Jember Daycare and 6 children who were cared for with criteria for pure daycare for children and school landfill children. Child Care Center is a form of Early Childhood Education institution that functions to be a substitute carer for families with learning programs that place more emphasis on children's life skills according to the age stage. As a family substitute institution in parenting, it is common practice to form a pattern of attachment to the relationship between a child and a caregiver. Caregivers act as a substitute for parents having duties and functions to stimulate aspects of child development. In a relationship like this there is a form of acceptance or rejection that affects the closeness of the child to the caregiver.
High Food Insecurity in Recyclers from Waste Sorting Units in Southern Brazil
Authors: Soares Cássia Medino , Saueressig Camila , Alves Bruna , Beskow Carolina Bortolin , Filho Paulo Roberto Taborda de Souza , Joveleviths Dvora , Dall’Alba Valesca
Published: July 2019

Background

In areas of greater social vulnerability, there are high levels of food insecurity, infectious diseases and diseases secondary to malnutrition. However, in Brazil, there are few studies with recyclers from waste sorting units, resulting in a lack of health promotion programs for this population. This study aimed to describe the prevalence of food insecurity in recyclers from waste sorting units in the south of Brazil.

Methods

Cross-sectional study conducted from May of 2017 to April of 2018 with adult individuals from two waste sorting units in the city of Porto Alegre, southern Brazil. Clinical and nutritional evaluations were performed in the work environment, and three questionnaires were applied: the Brazilian Scale of Food Insecurity, the Alcohol, Smoking and Substance Involvement Screening Test, and the International Questionnaire of Physical Activity.

Results

One hundred and twenty-three subjects were evaluated, mean age 35 years, 66% female. A 74% rate of food insecurity was detected. About 57% of the participants presented overweight or obesity and 48% presented increased waist circumference.

Conclusion

Subjects presented high levels of Food Insecurity and immediate need of intervention for tobacco and alcohol abuse. There is a need for multidisciplinary interventions to prevent the situations found and the implementation of public policies addressing health promotion acts in the population of recyclers.
MASKED GENOTYPE 6 OF BOVINE LEUKEMIA VIRUS IS FOUND IN COLOMBIAN CATTLE
Authors: Corredor-Figueroa Adriana Patricia , Olaya-Galán Nury Nathalia , Salas Sandra Patricia , Quintero Juan Sebastián , Fajardo Álvaro , Soñora Martín , Moreno Pilar , Cristina Juan , Sánchez Alfredo , Tobón Julio , Ortiz Diego , Gutierrez María Fernanda
Published: July 2019

Background

Viral diseases such as bovine leukosis are a major cause of health problems associated with economic losses in the livestock industry worldwide. The prevalence of bovine leukosis ranges between 4% and 90%, and this disease is considered endemic. The etiological agent is bovine leukemia virus (BLV). Ten BLV genotypes have been reported based on analysis of complete or partial envelope gene sequences, of which genotype 1 is the most prevalent. However, the genetic variability of BLV variants circulating in Colombia remains unexplored. Therefore, in the present study, we analyzed blood samples collected from 289 cows distributed in 75 farms across the country. PCR amplification of env, gag and tax gene segments was performed. The obtained amplicons were sequenced and then subjected to phylogenetic analyses.

Results

A total of 62% of the cows present at 92% of the farms were BLV-positive. Genotype 1 was exclusively detected by env and gag gene segments when analyzed using previously reported primers. However, tax gene analysis revealed circulation of genotype 6 variants, which were also detected based on env gene analysis with newly designed primers. These results indicate that current genotyping approaches based on partial env sequencing may bias BLV genetic variability approaches and underestimate the diversity of the detected BLV genotypes.

Conclusions

This report is the first molecular and epidemiological study of BLV conducted in Colombia and contributes to the global epidemiology of the virus; it also reinforces the great impact of BLV on the country’s livestock and thus is a useful resource for farmers and government entities.
Safety and efficacy of en bloc transurethral resection versus conventional transurethral resection for primary nonmuscle-invasive bladder cancer：a meta-analysis
Authors: zhang dong , yao lifeng , yu sui , cheng yue , jiang junhui , ma qi , yan zejun
Published: July 2019

Abstract
Background: The purpose of this meta-analysis is to compare the safety and efficacy of en bloc transurethral resection of bladder tumor（EBRT） versus conventional transurethral resection of bladder tumor（CTURBT）.
Methods: We performed a meta-analysis of relevant articles through January 2019 using PubMed, Embase and Cochrane Central Register to compare the safety and efficacy of EBRT versus CTURBT. The main endpoint included the operation time（OT）, hospitalization time（HT）, catheterization time（AT），perioperative period complications, bladder detrusor muscle found in the specimen, the residual tumor on the base, the ratio of the same site recurrence and 12/24/36-month recurrence rate. Cochrane Collaboration’s Revman software, version 5.3, was used for statistical analysis.
Results: A total of 19 studies with 2651 patients were included，1369 underwent EBRT and 1282 underwent CTURBT. Patients treated with EBRT had a significantly lower AT, HT, obturator nerve reflex, bladder perforation, bladder irritation, postoperative complications and 24-month recurrence rate than those who underwent CTURBT. While no significant difference was found in terms of OT, the ratio of bladder detrusor muscle found in the specimen, the residual tumor on the base, 12-month recurrence rate, 36-month recurrence rate and the ratio of the same site recurrence. In mitomycin subgroup, EBRT was superior to CTURBT in terms of 12/24-month recurrence rate. Similarly, in the prospective subgroup and retrospective subgroup, EBRT had a lower 24-month recurrence rate than CTURBT. However, no significant difference was found in the low, intermediate and high-risk group in the light of 12-36 month recurrence rate.
Conclusions: Based on the included 19 articles, EBRT had a significantly lower AT, HT, intraoperative and postoperative complications and 24-month recurrence rate than those treated with CTURBT. Well designed randomized controlled trials were needed to reevaluate these outcomes.
Trial registration: This meta-analysis was reported in agreement with the PRISMA statement and was registered on PROSPERO 2019CRD42019121673.
Keywords: bladder tumor; en bloc transurethral resection; conventional transurethral resection of bladder tumor; meta-analysis; complication
Exploring an Energy Management Approach to Improve Fatigue and Life Participation in Adults on Chronic Dialysis
Authors: Farragher Janine F. , Polatajko Helene J. , McEwen Sara , Jassal Sarbjit V.
Published: July 2019

Background

Fatigue and its negative impact on life participation are top research priorities of people on chronic dialysis therapy. Energy management education is a fatigue management approach that teaches people to use practical strategies (e.g. prioritizing, using efficient body postures, organizing home environments) to manage their energy expenditure during everyday life. The study objective was to explore if energy management education is associated with improvements in fatigue and life participation in adults on chronic dialysis.

Methods

This study consisted of five single-case, interrupted time-series AB studies, and follow-up qualitative interviews. Participants on chronic dialysis therapy at an academic hospital in Toronto, Canada were purposively selected to represent diversity in age, gender and modality. All 5 participants underwent “The PEP Program”, a personalized, web-supported energy management education (EME) program designed to meet the needs of people on dialysis. During the program, participants complete two brief web modules about energy management, and then use energy management principles and a problem-solving framework to work on 3 life participation goals during sessions with a trained program administrator. Fatigue and life participation were measured weekly using short questionnaires during the baseline and intervention periods, and additional validated questionnaires (the Fatigue Impact Scale, SF36 Vitality Scale, & Canadian Occupational Performance Measure) were administered pre- and post-intervention. Data were analyzed using visual analysis and the Tau-U statistic for the weekly time-series data, and thematic analysis for the qualitative interviews.

Results

Three of five participants displayed a consistently positive response to the PEP program across multiple measures of fatigue and life participation. Tau-U effect size estimates ranged from small to moderate, according to the time-series data. All five participants expressed that the program had benefitted them in qualitative follow-up interviews, with the most common reported benefit being that the program made day-to-day activities easier. The format of the program was also said to be feasible and convenient.

Conclusions

The PEP program has potential to improve fatigue-related outcomes in people on chronic dialysis. Larger, controlled studies of the program are now warranted.
Raspberry Growers’ Perceptions and Practices Regarding Soil Quality, Cover Crops, and Fumigation
Authors: Rudolph Rachel E. , DeVetter Lisa W. , Benedict Chris , Zasada Inga A.
Published: July 2019

A survey was conducted in Washington State in 2015 and 2016 to gauge grower perceptions, understanding, and current practices regarding soil quality. Soil quality has been defined as the ability of the soil to sustain plants, animals, and humans over time. Many current practices of modern agriculture can be detrimental to soil quality, including soil tillage and soil fumigation, both of which are commonly used for the Washington red raspberry (Rubus idaeus) production system. The area between red raspberry beds, known as the alleyway, is frequently tilled and kept bare, without groundcover, to manage weeds. Growers commonly fumigate the soil before planting red raspberry to manage soilborne pathogens and plant-parasitic nematodes. The majority of red raspberry growers surveyed consider soil quality quite often in relation to the management of their fields. The majority of growers during both years considered cover crops to have a positive impact on soil quality. However, growers also perceived soil fumigation to have a positive impact on soil quality. The majority of growers responded that they were willing to adopt alleyway cover crops for a variety of reasons, including improving red raspberry production, physical soil quality, and beneficial soil microorganism populations. This survey demonstrated that there is interest in soil quality among growers; however, there is a difference in perceptions between growers and researchers regarding how management practices impact soil quality.
GANGGUAN KOGNITIF PADA EPILEPSI
Authors: Lukas Andre , Harsono Harsono , Astuti Astuti
Published: July 2019

Epilepsi merupakan salah satu penyakit dalam bidang neurologi yang insidensi dan prevalensinya terus meningkat. Penurunan fungsi kognitif yang sering ditemukan pada epilepsi sangat bergantung pada beberapa faktor antara lain etiologi, tipe bangkitan, sindrom epilepsi tertentu (epilepsi idiopatik umum, epilepsi absans, juvenile myoclonic epilepsy, epilepsi lobus temporal, epilepsi lobus frontal, dll), letak lesi atau fokus bangkitan, frekuensi dan durasi bangkitan, umur saat onset, adanya gangguan psikis lain seperti kecemasan dan depresi, serta obat anti-epilepsi yang diminumnya.

Pada sebagian besar epilepsi, gangguan kognitif yang sering terjadi adalah gangguan pada atensi, psikomotor, visuospasial, memori dan fungsi eksekutif. Sindrom epilepsi tertentu seperti sindrom Ohtahara, West, Lennox Gastaut, CSWS (Continous Spike-Waves during Sleep Syndrome), dan Landau Kleffner Syndrome menunjukkan defisit kognitif yang lebih berat.

Manajemen epilepsi yang meliputi terapi farmakologis maupun terapi bedah berhubungan dengan munculnya gangguan kognitif pada penderita epilepsi. Walaupun obat anti-epilepsi generasi baru memiliki efek negatif terhadap fungsi kognitif yang lebih kecil dibandingkan dengan obat antiepilepsi generasi lama, namun penggunaannya termasuk dosis harus tetap hati-hati karena beberapa obat anti-epilepsi generasi baru juga berhubungan dengan penurunan fungsi kognitif yang nyata.