bluuebunny/crossref_metadata_2025 huggingface dataset:
Nutritional, physicochemical and sensory evaluation of biscuits enriched with
Ulva sp. from Gunungkidul coast
Authors: Perdani A.W. , Ratnaningsih N. , Chayati I. , Utami N.N.
Published: March 2024

Ulva sp. a seaweed commonly found on Gunungkidul coast, had the potential as a source
of functional food that contained high antioxidants, protein and dietary fiber. Ulva sp. was
developed into biscuits, one of the most popular foods in Indonesia. This study aimed to
investigate the physicochemical and sensory evaluation of biscuits enriched with Ulva sp.
The nutritional value, antioxidant activity, dietary fiber, texture, color, appearance and
sensory evaluation were studied. Ulva sp. was collected from Gunungkidul coast and
treated using 5% lime for fishy-smell removal, then dried to produce Ulva sp. powder.
The Ulva sp. powder was used for biscuit enrichment with 0% powder (STD), 3% powder
(BC3), 5% powder (BC5) and 7% powder (BC7) substitution. Biscuits enriched with Ulva
sp. increased the protein, fat, and ash content, while the carbohydrate content decreased
(p<0.05). The more Ulva sp. was substituted in biscuits, the higher antioxidant activities
and dietary fibers were measured (p<0.05). The crunchiness of BC5 (139.95±28.84 Nmm)
was high, and no significant difference with STD (393.05±34.11 Nmm), while the
crispiness and the hardness of enriched biscuits were lower than STD. The lightness (L*),
redness (a*), and yellowness (b*) of enriched biscuits were lower than STD because
the Ulva sp. powder contributed to giving dark-greenish colors. Sensory evaluation
showed that BC5 was the most well-liked by the panellist in terms of its appearance,
aroma, taste, flavor, texture, aftertaste, and overall (there was no difference with STD).
Thus, biscuits enriched with Ulva sp. were confirmed to improve nutritional and
physicochemical, and it has sensory evaluation acceptance.
The effect of alginate extract on the properties of brown rice (Oryza nivara) ice
cream
Authors: Nuary R.B. , Maghfira L.L. , Suleman D.P. , Rochmah A.N. , Zulfa F. , Anandita R.B.K.
Published: March 2024

The production of ice cream with the basic ingredients of brown rice milk is carried out to
increase the consumption of antioxidants derived from brown rice (Oryza nivara). This is
because the plant is less consumed due to its rough texture. The recent development of
brown rice ice cream (BRICE) is intended to expand the use of the plant into a common
commodity. Previous investigations have established that stabilizers are required in ice
cream production, although only a few used natural stabilizers such as alginate. Therefore,
this study aimed to determine the effect of adding the different concentrations of alginate
from brown seaweed Laminaria sp. on the physical characteristic, namely melting power,
viscosity, overrun, total dissolved solids, chemical properties, which include protein, fat,
as well as antioxidant activity and hedonic level of BRICE. The concentration of alginate
used was at 0.025%, 0.05%, 0.075%, and 0.1%, while the data collected were analyzed
using analysis of variance (ANOVA) and Duncan’s test. The result showed that the
addition of different alginate concentrations had a significant effect on the value of the
parameters observed.
Konutun Toplumsal Boyutu Üzerine Karşılaştırmalı Bir Analiz
Authors: Küçükyazıcı Ufuk , Alkışer Bregger Yasemin
Published: March 2024

Konut alanları, toplumsal yapı, ekonomi, bilgi teknolojilerindeki gelişmeler etkisiyle sosyal ve fiziki çevre etkileşimi ile birlikte mekânsal organizasyon açısından gündelik hayat alışkanlıklarına göre kamusal ve özel alan arası geçirgenlikleri içermektedir. Bu anlamda konut sorunu bireysel ihtiyaçların yanı sıra toplumsal boyutları bulunan ve sosyal, ekonomik, kültürel unsurlardan etkilenen çok katmanlı bir yapı göstermektedir. Bu çalışmada, konutun toplumsal boyutu kavramı ile konut sorununun ekonomik boyutunun yanı sırada konut kullanıcılarının yaşadıkları çevredeki mekânsal etkinlikleri ile birey ve toplum etkileşimi açısından oluşturdukları toplumsal kurgu ile fiziksel çevre etkileşiminin tartışılması amaçlanmaktadır.

İki temel kısımdan oluşan çalışmanın ilk kısmında konutun toplumsal boyutunu içerdiği düşünülen; karşılanabilir konut, toplu konut, sosyal konut, kooperatif konut ve paylaşımlı konut olmak üzere beş konut türü etimolojik ve kavramsal olarak incelenmektedir. Çalışmanın ikinci kısmında ise, 2000 yılından sonra tamamlanmış ve kullanımda olan ikişer örnek konut alanı üzerinde mekânsal analizler yapılmaktadır. Bu analizler sonucunda farklı konut türlerinin birbirini içerdiği ve üst üste düştüğü durumlar ortaya konulmaktadır. Bu çalışma konutun toplumsal boyutunu vurgulayarak ekonomik, sosyal ve kültürel katmanları tartışmaya açmaktadır. Birey ve toplum etkileşimine odaklanarak kullanıcıları odaklı karşılanabilir konut üretimine dair kapsayıcı modellerin önemine dikkat çekmektedir. Bu çalışma, toplumsal ve mekânsal etkileşimlerin daha iyi anlaşılması ve gelecekteki konut politikalarının şekillendirilmesi açısından önemli bir katkı sunmaktadır.
Mimarlık Temel Alanı Terminolojisinde “Görev Aydınlatması”: Bir Kavram Analizi
Authors: Ünlü Selen Rumeysa , Aydıntan Erkan
Published: March 2024

Mimarlık temel alanı literatüründe, “Görev Aydınlatması” kavramının; kapsamlı bir tanımının yapılmamış olduğu, mimarlık disiplinine özgü sözlüklerin büyük çoğunluğunda yer almadığı ve kendisi yerine başka kavramlar kullanılabildiği tespit edilmiştir. Bu durum, özellikle bilimsel yazılarda anlam karmaşasına yol açabilmektedir. Çalışmada bu kavramın, diğer aydınlatma türleri ile olan ilişkisi üzerinden analiz edilip, temel özellikleri ile birlikte açıklanabileceği hipotezi öne sürülmüştür.

Çalışma sürecinde öncelikle “Görev Aydınlatması” kavramının literatürde nasıl tanımlandığı ele alınmış, bu amaçla aydınlatma türlerinin tanımlandığı kaynaklar analiz edilmiştir. Elde edilen veriler, Rodgers’ın gelişimsel kavram analizi ile Walker ve Avant’ın kavram analizi yöntemiyle değerlendirilmiştir. Süreçte kapsamlı ve doğru bir tanımlama yapabilmek için bilgilerin devamlı olarak tartışılması amaçlanmış, bu sebeple kavramların ifade edilmesi noktasında önemli bir bakış açısı sunan gömülü teori yönteminden faydalanılmıştır. Çalışma sonucunda, incelenen aydınlatma türlerinin birbirleri yerine kullanılabildiği ve birbirlerinin tanımsal karşılıklarını kendi bünyelerinde barındırabildiği anlaşılmıştır. Ulaşılan diğer sonuç ise yapılan aydınlatma tanımlamalarının, bu aydınlatma türlerinin en belirgin özellikleri üzerinden gerçekleştirildiğidir. Çalışma sonucunda “Görev Aydınlatması”nın; belirli bir işleve yönelik olma, kullanıcı odaklı olma, işlevlerin tamamlanmasını kolaylaştırma, görsel algılamayı iyileştirme ve tehlikeli durumları görünür kılma özelliklerine sahip olduğu görülmüştür. Bu aydınlatma türünün bir başka özelliği de iş ve kullanıcı odaklı olması ve profesyonel/kişisel çalışma alanları ile ticari alanlarda kullanılmasıdır.
FÓSSEIS DA AMAZÔNIA: UMA ANÁLISE A PARTIR DO GEOPATRIMÔNIO DE SALINÓPOLIS, PARÁ, BRASIL
Authors: Sepulvreda Barbara Alves , Costa Sue Anne Regina Ferreira da , Lima Aline Maria Meiguins de
Published: March 2024

A proteção da geodiversidade apresenta possibilidades para a ampliação das concepções sobre natureza e cultura. Contudo, em Salinópolis (Pará) o registro fóssil se mostra distante da sociedade e das políticas públicas. Dessa forma, este estudo objetivou compreender a atual situação da geoconservação dos fósseis de Salinópolis pelos vieses do aporte teórico científico e da percepção dos gestores públicos municipais. Foi possível constatar que existe um extenso acervo de fósseis da Formação Pirabas, porém há uma falta de diálogo entre as instituições públicas responsáveis pela salvaguarda do geopatrimônio e a prefeitura de Salinópolis. Percebe-se, portanto, a necessidade de mudar as concepções sobre o patrimônio fóssil da cidade, de modo a estreitar as relações socioambientais, possibilitando a democratização das relações científico-sociais, ressaltando a coletividade do patrimônio geoambiental amazônico.
VARIAÇÕES DA LINHA DE COSTA DA ENSEADA DA PAJUÇARA, ENTRE 1955 E 2020, MACEIÓ-AL: UMA ANÁLISE PELO MÉTODO EPR
Authors: Silva Thiago Cavalcante Lins , Ferreira Bruno , Diniz Marco Túlio Mendonça
Published: March 2024

As linhas de costa representam uma submorfologia marcante, representando importantes testemunhos de processos de remoção e inserção de areia na praia.  Pensando nisso, o presente estudo buscou analisar as variações das linhas de costa da Enseada da Pajuçara, entre 1955 até 2020, sendo aplicado o modelo EPR4Q 3.14 para o cálculo das taxas de variações entre os anos, utilizando para isso dados de satélite e fotografias aéreas, processadas através do software QGIS 3.14. Os resultados demonstraram que grande parte da porção sul e central da Enseada obteve valores compatíveis com equilíbrio com valores entre 0,5 até -0,5 m/a, enquanto que uma pequena porção no norte foram encontrados processos erosivos com variações com taxas de -0,5 até -1 m/a. Nestas porções ainda foram encontradas diversas estruturas de contenção, que se mostraram não tão efetivas na contenção de marés meteorológicas, necessitando de estruturas mais efetivas ou o estabelecimento de projetos de gestão de orla efetivos, que se não aplicados pode intensificar ou mesmo dobrar a ação dos processos erosivos em perspectivas futuras. Os dados gerados podem ser incorporados em planos de gestão visando a conservação e recuperação das áreas.
COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA.1/BA.2 lineages among adults and adolescents in a multicentre primary care study, Europe, December 2021 to June 2022
Authors: Lanièce Delaunay Charlotte , Martínez-Baz Iván , Sève Noémie , Domegan Lisa , Mazagatos Clara , Buda Silke , Meijer Adam , Kislaya Irina , Pascu Catalina , Carnahan AnnaSara , Oroszi Beatrix , Ilić Maja , Maurel Marine , Melo Aryse , Sandonis Martín Virginia , Trobajo-Sanmartín Camino , Enouf Vincent , McKenna Adele , Pérez-Gimeno Gloria , Goerlitz Luise , de Lange Marit , Rodrigues Ana Paula , Lazar Mihaela , Latorre-Margalef Neus , Túri Gergő , Castilla Jesús , Falchi Alessandra , Bennett Charlene , Gallardo Virtudes , Dürrwald Ralf , Eggink Dirk , Guiomar Raquel , Popescu Rodica , Riess Maximilian , Horváth Judit Krisztina , Casado Itziar , García Mª del Carmen , Hooiveld Mariëtte , Machado Ausenda , Bacci Sabrina , Kaczmarek Marlena , Kissling Esther ,   on behalf of the European Primary Care Vaccine Effectiveness Group
Published: March 2024

Background

Scarce European data in early 2021 suggested lower vaccine effectiveness (VE) against SARS-CoV-2 Omicron lineages than previous variants.

Aim

We aimed to estimate primary series (PS) and first booster VE against symptomatic BA.1/BA.2 infection and investigate potential biases.

Methods

This European test-negative multicentre study tested primary care patients with acute respiratory symptoms for SARS-CoV-2 in the BA.1/BA.2-dominant period. We estimated PS and booster VE among adults and adolescents (PS only) for all products combined and for Comirnaty alone, by time since vaccination, age and chronic condition. We investigated potential bias due to correlation between COVID-19 and influenza vaccination and explored effect modification and confounding by prior SARS-CoV-2 infection.

Results

Among adults, PS VE was 37% (95% CI: 24–47%) overall and 60% (95% CI: 44–72%), 43% (95% CI: 26–55%) and 29% (95% CI: 13–43%) < 90, 90–179 and ≥ 180 days post vaccination, respectively. Booster VE was 42% (95% CI: 32–51%) overall and 56% (95% CI: 47–64%), 22% (95% CI: 2–38%) and 3% (95% CI: −78% to 48%), respectively. Primary series VE was similar among adolescents. Restricting analyses to Comirnaty had little impact. Vaccine effectiveness was higher among older adults. There was no signal of bias due to correlation between COVID-19 and influenza vaccination. Confounding by previous infection was low, but sample size precluded definite assessment of effect modification.

Conclusion

Primary series and booster VE against symptomatic infection with BA.1/BA.2 ranged from 37% to 42%, with similar waning post vaccination. Comprehensive data on previous SARS-CoV-2 infection would help disentangle vaccine- and infection-induced immunity.
Questioning risk compensation: pre-exposure prophylaxis (PrEP) and sexually transmitted infections among men who have sex with men, capital region of Denmark, 2019 to 2022
Authors: von Schreeb Sebastian , Pedersen Susanne Kriegel , Christensen Hanne , Jørgsensen Kristina Melbardis , Harritshøj Lene Holm , Hertz Frederik Boetius , Ahlström Magnus Glindvad , Lebech Anne-Mette , Lunding Suzanne , Nielsen Lars Nørregaard , Gerstoft Jan , Kronborg Gitte , Engsig Frederik N
Published: March 2024

Background

Pre-exposure prophylaxis (PrEP) effectively prevents HIV, but its association with sexually transmitted infections (STIs) has raised concerns about risk compensation, potentially impacting the expansion of PrEP programmes.

Aim

We examined the relationship between PrEP and the incidence of chlamydia, gonorrhoea and syphilis.

Methods

In this prospective cohort study, we compared STI rates before and after PrEP initiation among users in the capital region of Denmark (2019–2022), calculating incidence rate ratios adjusted for age and testing frequency (aIRR). To pinpoint when increases began, we plotted weekly STI rates, adjusting the timeline to correspond with PrEP initiation.

Results

The study included 1,326 PrEP users with a median age of 35 years. The STI incidence rate per 100,000 person-years rose from 35.3 before to 81.2 after PrEP start, with an aIRR of 1.35 (95% CI: 1.18–1.56). Notably, this increase preceded PrEP initiation by 10–20 weeks. Specific aIRR for chlamydia, gonorrhoea and syphilis were 1.23 (95% CI: 1.03–1.48), 1.24 (95% CI: 1.04–1.47) and 1.15 (95% CI: 0.76–1.72), respectively. In subanalyses for anatomical sites aIRR was 1.26 (95% CI: 1.01–1.56) for rectal chlamydia and 0.66 (95% CI: 0.45–0.96) for genital gonorrhoea.

Conclusion

We found a 35% increase in STI incidence associated with PrEP use. It started before PrEP initiation, challenging the assumption that PrEP leads to risk compensation. Instead, the data suggest that individuals seek PrEP during periods of heightened sexual risk-taking. Consequently, PrEP programmes should include sexual health consultations, STI testing, treatment and prevention strategies to prevent HIV and improve sexual health.
Atypical age distribution and high disease severity in children with RSV infections during two irregular epidemic seasons throughout the COVID-19 pandemic, Germany, 2021 to 2023
Authors: Cai Wei , Köndgen Sophie , Tolksdorf Kristin , Dürrwald Ralf , Schuler Ekkehard , Biere Barbara , Schweiger Brunhilde , Goerlitz Luise , Haas Walter , Wolff Thorsten , Buda Silke , Reiche Janine
Published: March 2024

Background

Non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic affected respiratory syncytial virus (RSV) circulation worldwide.

Aim

To describe, for children aged < 5 years, the 2021 and 2022/23 RSV seasons in Germany.

Methods

Through data and 16,754 specimens from outpatient sentinel surveillance, we investigated RSV seasonality, circulating lineages, and affected children’s age distributions in 2021 and 2022/23. Available information about disease severity from hospital surveillance was analysed for patients with RSV-specific diagnosis codes (n = 13,104). Differences between RSV seasons were assessed by chi-squared test and age distributions trends by Mann–Kendall test.

Results

RSV seasonality was irregular in 2021 (weeks 35–50) and 2022/23 (weeks 41–3) compared to pre-COVID-19 2011/12–2019/20 seasons (median weeks 51–12). RSV positivity rates (RSV-PR) were higher in 2021 (40% (522/1,291); p < 0.001) and 2022/23 (30% (299/990); p = 0.005) than in prior seasons (26% (1,430/5,511)). Known globally circulating RSV-A (lineages GA2.3.5 and GA2.3.6b) and RSV-B (lineage GB5.0.5a) strains, respectively, dominated in 2021 and 2022/23. In 2021, RSV-PRs were similar in 1 – < 2, 2 – < 3, 3 – < 4, and 4 – < 5-year-olds. RSV hospitalisation incidence in 2021 (1,114/100,000, p < 0.001) and in 2022/23 (1,034/100,000, p < 0.001) was approximately double that of previous seasons’ average (2014/15–2019/20: 584/100,000). In 2022/23, proportions of RSV patients admitted to intensive care units rose (8.5% (206/2,413)) relative to pre-COVID-19 seasons (6.8% (551/8,114); p = 0.004), as did those needing ventilator support (6.1% (146/2,413) vs 3.8% (310/8,114); p < 0.001).

Conclusions

High RSV-infection risk in 2–4-year-olds in 2021 and increased disease severity in 2022/23 possibly result from lower baseline population immunity, after NPIs diminished exposure to RSV.
Molecular epidemiology identifies the expansion of the DENV2 epidemic lineage from the French Caribbean Islands to French Guiana and mainland France, 2023 to 2024
Authors: Klitting Raphaëlle , Piorkowski Géraldine , Rousset Dominique , Cabié André , Frumence Etienne , Lagrave Alisé , Lavergne Anne , Enfissi Antoine , Dos Santos George , Fagour Laurence , Césaire Raymond , Jaffar-Bandjee Marie-Christine , Traversier Nicolas , Gérardin Patrick , Amaral Rayane , Fournier Lucie , Leon Lucie , Dorléans Frédérique , Vincent Muriel ,   arbovirus genomics diagnostic laboratories working group, Fontaine Albin , Failloux Anna-Bella , Ayhan Nazli , Pezzi Laura , Grard Gilda , Durand Guillaume André , de Lamballerie Xavier
Published: March 2024

In 2023, dengue virus serotype 2 (DENV2) affected most French overseas territories. In the French Caribbean Islands, viral circulation continues with > 30,000 suspected infections by March 2024. Genome sequence analysis reveals that the epidemic lineage in the French Caribbean islands has also become established in French Guiana but not Réunion. It has moreover seeded autochthonous circulation events in mainland France. To guide prevention of further inter-territorial spread and DENV introduction in non-endemic settings, continued molecular surveillance and mosquito control are essential.
Viés Alternativo Para a Compreensão do Mundo? Uma Análise da Percepção de Graduandos em Ciências Biológicas Sobre Pseudociência
Authors: Damasceno Matheus Lau , Sedano Luciana
Published: March 2024

Pseudoscience is able to deceive even the most skeptical individuals due to its tactic of mimicking the processes of science, from simulating a methodology and a scientific language, to inducing a rationality. Therefore, considering this trick of pseudoscience, this study aimed to analyze the perception of undergraduate students in Biological Sciences about the general characteristics of pseudoscience, since these students are in the process of training and may act to combat the anti-science front. To achieve our goal, we applied a questionnaire of agreement with a Likert-type scale, and its results were analyzed from the average ranking of the answers obtained. In total, 56 undergraduate and 32 bachelor students participated. The results of the research show that students do not differentiate scientific denialism from pseudoscience and remain in a field of neutrality, when dealing with the criterion of falsifiability to characterize the Sciences.
RUSSIAN UM: GENESIS AND NATIONAL DISTINCTIONS OF THE CONCEPT IN GRIBOEDOV'S COMEDY
Authors:   National Research Tomsk State University, Ablogina Evgeniia
Published: March 2024

The plays of A.S. Griboedov become the subject of a novel study as the semiosphere of um (roughly: mind), the title concept of um seen as its semantic core, an anthropological, epistemic and aesthetic foundation. The article discusses the origin and the essence of the concept of um in the early and mature drama of Griboedov. It argues that in his early loose translations and adaptations from French classical playwrights A.-F.C. Creuzé de Lesser and N.-T. Barthe the concept is being formed as a motif. Originally rooted in the era of French classicism, it receives significant reinterpretation. Similarly and remarkably does the German one as can be seen from Griboedov's adaptation of J.W. Goethe's “Vorspiel auf dem Theater”. In original early plays of Griboedov, it expands its semantics by accumulating of new motifs; in mature ones, it significantly increases its frequency and level up by acquiring the status of a concept. Semantic universals of Griboedov's artistic thinking embodied in his text and revealed in the study demonstrate an integral conceptual program.
GRIBOEDOV'S PERSONALITY AND FATE IN THE ELEGIES OF W.K. KUKHELBECKER AND A.I. ODOYEVSKY
Authors:   Donbas State Pedagogical University, Zhuzhgina-Allahverdian Tamara
Published: March 2024

A romantic image of A.S. Griboedov as a friend, poet and statesman emerges in the elegies of his contemporaries, his close friends and associates W.K. Kukhelbeker and A.I. Odoyevsky. Textual analysis of elegy poems, dedications and other poems “on the death of” provides grounding of the statement that Romantic poets, inspired by the ideas of a poet-in-chief and visionary in the spirit of the time, created an image of a writer and diplomat in accordance with their aesthetic ideals and transformed the elegy genre by giving it rebellious features in the spirit of Decembrist lyrical and philosophical tradition, expressing in them high thoughts and feelings, personal ideals and dreams, filling with reflections on the meaning of life and death, on the “divine gift” of poetry, on the “evil fate” of a lonely sufferer. The article argues that in the Decembrist poetry of 1820-1840 the spiritual values of man are brought to the forefront and defined by loyalty to the poetic ideals, despite the harsh “prose of life”; it is within this framework that the priceless personal qualities, the outstanding mind and talents of Griboedov, his creative and “passionate impulses” are valued. Grieving over the tragic death of Griboedov, the Decembrists lamented the insidious fate that did not favor the servants of poetry and the holders of a prophetic gift; they symbolically summarized and reflected on the poet and diplomat's life and work as well as their own fate in a long line of outcasts and deplorables. The author's personal experiences, impressions and moods did not contradict the Romantic notions of poetry and its role in the life of mankind, and resonated ideologically and emotionally with the lyrical sentiments of the elegiac predecessors.
ARTISTIC FEATURES OF THE PLAY “CHATSKY'S RETURN TO MOSCOW” BY E.P. ROSTOPCHINA
Authors:   Smolensk State Institute of Arts, Buteev Dmitry
Published: March 2024

The article examines the work “Return of Chatsky to Moscow, or The Meeting of Familiar Faces after Twenty-Five Years of Separate”. This is a continuation of the play by A.S. Griboedov “Woe from Wit”, created in 1856 by E.P. Rostopchina, a Russian poet, translator, playwright and prose writer, a mistress of a literary salon. The article reveals the artistic features of the play, assesses the characters, composition, speech design, ideological plan of the drama. The play is analyzed both in the context of Rostopchina, and in the context of the socio-literary trends of the era (mid-19th century). In addition, the report gives an assessment of the performance staged by the national drama theater of SSMU “Mirror” (directed by S.N. Sinitsyn). It organically combines two literary works - by Griboedov and by Rostopchina, deepens the socio-philosophical plan, the artistic material of the 19th century is updated by attaching motives from late 20th-century literature (Kys' by T.N. Tolstaya). The scientific novelty of the article derives from the fact that the analyzed texts (the play by Rostopchina and the play “Mirrors”) have not yet been thoroughly scholarly reflected on.
“GORE OT OUMA” TRANSLATED BY NICOLAS BENARDAKY: ASPECTS OF TEXT INTERPRETATION
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Sholokhova Anna
Published: March 2024

The article provides a brief overview of A.S. Griboedov's comedy “Woe from Wit” in English translation performed by Nicolas Benardaky in 1857. This translation attracts our interest primarily because it was the first attempt to introduce the comedy to an English-speaking reader and to form a certain perception of the play in the English-speaking environment. It is important to note that version by Benardaky was made in prose and based on a different principle of text construction than the original. Significantly it is characterized by the fact that interpretation reproduces as closely as possible the semantic meaning of Russian language units and their notional component. As a result of such genre transformation, all sorts of stylistic, lexical and semantic changes certainly occur. With a general correct semantic perception, the movement and ease of reading is lost in translation, as well as the additional connotative definitions formed by rhythm and syntax. However, the choice of this method of translation was largely due to the established tradition, when the main goal of translator was not yet to preserve the style of the original and its manner, the task was simpler - to convey the plot of the work.
COSTUME SKETCHES FOR THE COMEDY OF GRIBOEDOV “WOE FROM WIT” BY THE ARTIST NIKOLAY ZARETSKY
Authors:   State Historical Museum, Bukreeva Elena
Published: March 2024

For the first time in scientific circulation 17 drawings for the comedy “Woe from Wit” created in 1935 by the artist Nikolay Zaretsky (1876-1959) are studied. These are costume sketches prepared for an unrealized theatrical production in Prague. Until 1949, they were stored in Czechoslovakia and then their trace was lost. As a result of the research, the title pages and the sketches of the costumes were found; all stages of the receipt of works of original technology in the State Literary Museum have been clarified.
RETHINKING GRIBOEDOV BY THE PUBLICISTS OF THE SECOND WAVE OF EMIGRATION
Authors:   Institute of World History of Russian Academy of Sciences, Talalay Michail
Published: March 2024

The article examines the images of characters in A.S. Griboedov's play “Woe from Wit” rethought in the journalism of the “second wave” of Russian emigration: in contrast to the steady interpretation of Chatskii as an exponent of civil pathos against inertia, etc., now he appears as one of the initiators of the destruction of old Russia, while Molchalin, albeit given by Griboedov in a general satirical vein, is thought of as a creative character, striving for state building. The little-known program text of the émigré writer Boris N. Shiryaev (1949) and its possible sources are analysed. It is shown how the characters of the classical play are once again involved in the ideological struggle of different camps of the Russian emigration's intelligentsia.
PERCEPTION OF ALEKSANDR GRIBOEDOV'S PERSONA AND HIS LEGACY IN RUSSIA, IRAN, THE CAUCASUS AND BRITAIN
Authors:   University of Cambridge, Melville Firuza
Published: March 2024

The paper gives a brief analysis of the perception of Griboedov's persona and his legacy as a diplomat in those countries whose political history was greatly influenced by his professional activities. In Russia, he is mainly known as a playwright and composer although it was Griboedov who drafted the Turkmanchay Treaty according to which the country acquired the significant Persian territories in the Caucasus after its military successes. This suggests that in his own country he is not recognised as a talented diplomat due to the myth created right after the massacre in the Russian mission. According to this myth, or fake news, produced as a ‘Narrative of the Proceedings of the Russian mission to Persia' and published in the Blackwood's Edinburgh Magazine (vol. 28, 1830), Griboedov was accused of his own death being “professionally unsuitable”. The Narrative seems to be the result of the agreed collective efforts of the Foreign Offices of three countries: Russia, Persia and Great Britain, and needs drastic revision. In Iran, who lost its geopolitically extremely important northern territories, Griboedov is still associated with a global political catastrophe and humiliation, exacerbated by the “embarrassment” of “uncivilised behaviour” towards a foreign envoy. As a result, even in our days only a mentioning of his name instantly provokes a furious reaction, similar to the one that led to the Tehran tragedy in February 1828. In Armenia, Griboedov is a national hero, thanks to whom the Armenian families, moved to Persia several centuries earlier, were able to return to the Caucasus. In Azerbaijan, the reaction is naturally quite the opposite as this created the insoluble Qarabagh problem. In Georgia, the attitude towards Griboedov who used to be perceived a part of the local aristocratic establishment has changed dramatically since its independence. In recent years he has become increasingly associated with the idea of Russian colonial policy and imperial ambitions in the Caucasus. British diplomacy regarding Griboedov had the most successful results: his name was erased from the annals of the Great Game, the Russo-British ‘tournament of shadows' in Persia, in which he played a key role, but his case was ‘consigned to eternal oblivion'. This publication is an attempt to restore the historical justice and reputation of Griboedov as a brilliant diplomat and politician with stately mind.
THE ASIATIC DEPARTMENT IN THE TIMES OF GRIBOEDOV
Authors:   The State Hermitage museum, Korotkova Olga
Published: March 2024

Institutional center of all Eastern policy of the Russian Empire, the Asiatic department of the Ministry of Foreign Affairs was formed in Saint Petersburg in 1819. The paper discusses the organization and staff of the department during the first decade of its existence. For the first time in this respect special attention is given to contemporaries of Griboedov who were working at the Asiatic department and contributed Russian culture. Griboedov was one of those men who were engaged in sophisticated diplomatic practice while working in the main region of interests of the Russian Empire's foreign policy in Asia in the considered period. It is shown that the placement of diplomatic missions as well as particularities in the work of the Educational department of Eastern languages, attached to the Asiatic department, reflected its main goals - to establish and maintain political and commercial contacts with the Middle East which was the region of the Eastern Question, the centre of confrontation between European countries. Soon after the tragic death of Griboedov in Tehran, the Asiatic department moved from the mansion on the English Embankment to a new house of the Ministry of Foreign Affairs in the east wing of the General Staff building on the Palace square. This architectural monument was transferred to the State Hermitage in 1988, and from now on the museum carries a memory of the institution's early years.
REVISITING THE RECEPTION OF GRIBOEDOV IN IRAN
Authors:   Al-Zahra University, Кalashi Nahideh
Published: March 2024

Literary ties between Iran and Russia span several centuries. During the course of this period, the cultures interacted and enriched each other, partly owing to translations. Russian-Iranian cultural ties actively expanded in the late 18th and early 19th centuries, during the Qajar period of Iran's history. The present study discusses the perception of A.S. Griboedov's image and his literary heritage in Iran. Translators' approaches to the comedy “Woe from Wit” and Persian publications on Griboedov's main drama are thoroughly considered. The article also characterises the reception of Griboedov in modern Iran and points to the relevant Iranian studies, numerous translations of the play's title into Persian are considered based on the reviews of Iranian authors. It is emphasized that translation, as an attempt to globalize knowledge, creates cultural ties between non-linguistic groups and the task of the translator is to strengthen friendship between countries through translation and familiarize them with each other's culture.
PRE-FIRE MOSCOW IN PRINCESS E.A. VYAZEMSKAYA'S UNPUBLISHED LETTERS TO HER BROTHER P.A. VYAZEMSKY IN 1805-1806
Authors:   The State Museum-Estate «Ostafyevo»-«Russian Parnassus», Egereva Tatyana
Published: March 2024

The article is concerned with the everyday life and morals of the Moscow nobility of the A.S. Griboedov era by the example of the Princes Vyazemsky family. Unpublished letters in French of 1805-1806 from the Princess E.A. Vyazemskaya (married name Shcherbatova) to the Prince P.A. Vyazemsky, her younger brother, who studied in Petersburg in the boarding school of Pater Chizh, show us the world of feelings and thoughts of a young Moscow aristocrat of the beginning of the 19th century: her fondness for albums, balls and masquerades, the circle of acquaintances, the manor life of the Vyazemsky-Karamzin family in Ostafyevo near Moscow.
ABOUT KINSHIP RELATIONS OF THE SMOLENSK MILIEU OF THE GRIBOEDOVS
Authors:   Pashkov Dom Publishing House of the Russian State Library, Makarov Andrey
Published: March 2024

The article presents the history of involuntary identification of kinship relations of the Griboedovs' surrounding in their Smolensk estate Khmelita (now State Historical, Cultural and Nature Museum-Reserve Named after A.S. Griboedov “Khmelita”). For the first time, family ties were traced between the playwright A.S. Griboedov and Admiral P.S. Nakhimov through the Lykoshins and the Zhegalovs. The article also presents a photograph of Vladimir Ivanovich Lykoshin, Griboedov's childhood friend and his fifth cousin.
CASES OF THE THIRD SECTION OF HIS IMPERIAL MAJESTY`S OWN CHANCERY ON THE OPPOSITION SMOLENSK NOBILITY OF GRIBOEDOV'S TIME
Authors:   Lomonosov Moscow State University, Leontiev Yaroslav
Published: March 2024

An attempt to create a new secret society in Smolensk after the dissolution of the Union of prosperity was made by the Vyazemsky landowner I.D. Yakushkin together with M.A. Fonvizin, P. H. Grabbe and M.N. Muravyov. as a result, the yelninsky leader of the nobility, retired General P.P. Passek, was accepted into the society. A circle of people who can be called the «Fonvizin-Yakushkin Society» organized assistance to starving peasants, created peasant schools, and gathered the opposition nobility around them. The Passek estate was repeatedly visited by Decembrists (Yakushkin, P.G. Kakhovsky, V.K. Küchelbecker) and the opposition, of which the composition of the group «Smolensk free thinkers». In 1828, the Third Department Of His Imperial Majesty's own Chancellery received a denunciation from I.V. Sherwood-Verny, known for his treacherous role in the Decembrist case, who claimed that if not for the premature death of Passek in the spring of 1825, the arrests would have affected many local nobles who were distinguished by their political Fronde. In the investigation appointed by A.H. Benckendorff, it turned out that indeed some nobles and retired officers were afraid of arrests. Some of them were in close relationship with the Decembrists, as, for example, J.M. Povalo-Shveikovsky and A.P. Cherkasov. As a result, police supervision was established over them.
LIFE AT THE MUSEUM-RESERVE “KHMELITA” AS A RUSSIAN AND FAMILY HISTORY
Authors:   State Historical, Cultural and Nature Museum-Reserve named after A.S. Griboedov “Khmelita”, Kulakova Nadezhda
Published: March 2024

The paper covers the history of the Khmelita estate located in Vyazemsky district, Smolensk region, a unique monument of Elisabethan baroque, the place associated with the childhood and adolescent years of A.S. Griboedov. Materials on the history of the Griboedovs' family estate began to be collected in the second half of the XIX century, the most active part of the period of restoration. By the mid-twentieth century the estate had fallen into complete disrepair, many of the buildings were ruined. The article describes activities of P.D. Baranovsky and V.E. Kulakov aimed at revival of the manor complex and its museumification. Special attention is paid to the biography and labours of V.E. Kulakov who directed the restoration of the estate, founded the museums of A.S. Griboedov, P.S. Nakhimov and “Manor Bogoroditskoye”, became the first general director of the State Historical, Cultural and Natural Museum-Reserve of A.S. Griboedov “Khmelita”.
THE ESTATE WORLD OF GRIBOEDOV AND ITS RECEPTION IN THE LITERARY SPACE OF KHMELITA
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Skorokhodov Maxim
Published: March 2024

Russian estate space has surrounded A.S. Griboedov since his early childhood and throughout his life thanks to the summer residence in the family estate Khmelita in Smolensk province and his numerous travels during which he stayed in the estates of his friends and acquaintances. A Russian estate as a centre of cultural life and a place of socialising was important to the playwright and diplomat. His attention to the world of the estate - the main house, church, outbuildings, gardens, alleys, ponds etc. - was reflected in his travel sketches, letters and other texts. Revived by the architect V.E. Kulakov and his associates, Khmelita, currently called the State Historical and Cultural Museum-Reserve of Aleksandr Griboedov, is developing at the beginning of the 21st century as a modern literary estate, preserving the memory not only of the great playwright, but the entire culture of the estate. Permanent exhibitions and projects reveal the specifics of estate life. Just as in the XIX century Khmelita is a hospitable home, a place where you can meet artists and writers and view the exhibits telling about the key characters of Russian culture.
CULTURAL ENVIRONMENT OF THE MUSEUM-RESERVE «KHMELITA»
Authors:   Smolensk state institute of arts, Mertens Elena
Published: March 2024

The article gives an interpretation of the cultural environment concept in the scientific world which is used for the study of homestead culture, museification of cultural heritage sites. The article analyzes the cultural environment of the State Historical, Cultural and Nature Museum-Reserve Named after A.S. Griboedov “Khmelita”. The traditional and innovative forms of activity used in the museum-reserve are revealed. The results of a servey conducted among students studying at the department of Museology and the protection of cultural and natural heritage sites are presented, commented and addressed. It is concluded that the cultural environment of the museum is developing dynamically, however the traditions of the unique historical territory of Smolensk Province are well-preserved, too. Finally, some vectors of development of the Museum-reserve of A.S. Griboedov “Khmelita”, including as an innovative interactive platform for creativity, are proposed.
La planeación eficiente de materiales y los acuerdos comerciales sólidos con los proveedores promueven la recepción oportuna de insumos extranjeros en la Industria Cerámica de Baldosas
Authors: Acuña-Torres Mónica Liliana , Barrera-Guerra Jr Juan Lorenzo
Published: March 2024

La pandemia del COVID-19 generó desafíos en el control de inventarios de refacciones provenientes del extranjero en la industria de la baldosa cerámica, debido a restricciones en el movimiento de mercancías y el cierre temporal de fábricas, así como los cambios en patrones de consumo y la escasez de mano de obra, situaciones que empujaron a las organizaciones a gestionar de forma diferente los materiales. En esta investigación se analizaron los beneficios de tener niveles óptimos de inventario de refacciones, mediante la planificación eficiente de materiales y contratos sólidos con proveedores, para mitigar el riesgo de desabasto mencionado, esto mediante el método descriptivo consultando diversas fuentes literarias. En el proceso se encontró que la planificación eficiente de materiales empuja al abastecimiento oportuno de insumos, así también que los contratos sólidos con proveedores establecen bases consistentes para relaciones de colaboración beneficiosas que aseguren un flujo de suministros. De este proceso, se concluye que la planificación eficiente de materiales y los acuerdos comerciales adecuados con proveedores pudieran promover la recepción oportuna de refacciones extranjeras, por lo que estas prácticas son efectivas para mantener una cadena de suministro sana.
Prevalence of Sleep Apnea Syndrome Risk Factors Among Active Drivers and Their Association with Traffic Accidents: A Cross-Sectional Study
Authors: Çom Aybal Nilay , KANMAZ Anıl , ERDEM Feyzanur , PARLAK Elif Gulsum , ARICA Secil
Published: March 2024

Objective: The aim of this cross-sectional observational study was to investigate the prevalence of risk factors for obstructive sleep apnea syndrome (OSA) within the active driving population and to assess the association between
these risk factors and traffic accidents. Methods: Conducted with ethical approval, the study took place between March 15, 2022, and May 15, 2022, at XXX Hospital Family Medicine Polyclinic. Participants, meeting inclusion criteria
and providing voluntary informed consent, were selected from those seeking care. A structured questionnaire, including the Berlin Risk Scale and sociodemographic inquiries, as well as questions related to driving and licensure,
was administered through face-to-face interviews. Results: 250 participants, with a mean age of 37.86±13.42 years, were included in the study. Obesity was present in 17.6% of participants, and 51.2% had more than 10 years of driving
experience. Ten participants experienced accidents due to falling asleep while driving, with two encountering this situation multiple times. According to the Berlin Risk questionnaire, 19.2% of participants were identified as at
high risk for OSA. Significant associations were found between obesity and accidents related to falling asleep (p<0.001, p<0.001). Furthermore, increasing age and BMI were significantly correlated with a higher risk of OSA
(p<0.001). Conclusion: In conclusion, our study identified that 19.2% of licensed drivers were at risk for OSA based on the Berlin questionnaire. The results underscore the importance of addressing OSA risk factors, particularly
obesity, age, and BMI, among active drivers to enhance road safety and reduce the likelihood of accidents associated with sleep apnea.
Biomorphological features and antioxidant activity of mint species of non-hybrid origin growing in the North Caucasus region
Authors: Popov I.V. , Yakovleva S.G. , Popova O.I. , Samylina I.A. , Kovtun E.V. , Bokov D.O. , Tatarenko-Kozmina Т.Y.
Published: March 2024

Introduction. Modern researchers note the role of antioxidants in the correction of fat and carbohydrate metabolism, so the search for new raw materials for obtaining substances with antioxidant activity is relevant. Polyphenolic compounds are considered the most powerful natural antioxidants. Our attention was drawn to non-hybrid mint species growing in the North Caucasus region. Objective. Study of biomorphological features and economically valuable characteristics of the species Mentha L. (Lamiaceae), their phytochemical characteristics based on the content of essential oil and some phenolic compounds, determination of antioxidant activity to substantiate the prospects for use in medicine and pharmacy. Material and methods. The studies were carried out according to the methods of the State Pharmacopoeia (SP) XIV and XV editions. Samples of raw mint (M. arvensis L.), watermint (M. aquatica L.), longleaf mint (M. longifolia (L.) Huds.), flea mint (M. pulegium L.), m spicata (M. spicata L.), harvested in forest-steppe and steppe zones, as well as on mountain slopes, damp places, sometimes in wastelands, in North Ossetia – Alania, Karachay-Cherkessia, Kabardino-Balkaria and the Stavropol Territory in their natural places of growth (end of July–August 2021–2023). Objects were dried using the air-shadow method. Antioxidant activity was determined by amperometric and titrimetric methods. Results. Non-hybrid mint species growing in the North Caucasus contain essential oils, hydroxycinnamic and triterpene acids, flavonoids and polyphenolic compounds. The established antioxidant properties of hydroalcoholic extracts of mint species, in addition to the traditionally known choleretic and antispasmodic effects, can be considered significant for reducing body weight. Conclusion. The content of essential oil and polyphenolic compounds in various types of mint, as well as the established antioxidant properties of aqueous-alcoholic extracts, in addition to the traditionally known choleretic and antispasmodic effects, can be considered significant for weight loss.
Organization of pharmaceutical education of the adult population: from theory to practice
Authors: Shestakova T.V. , Kirshchina I.A. , Soloninina A.V. , Mikhailova V.N.
Published: March 2024

Introduction. Health literacy is defined by WHO as one of the reliable parameters that allow predicting the state of public health in the future. The level of health literacy is integral to the pharmaceutical literacy of the individual, since a significant part of the issues of health care is related to the use of medicines (LP). Pharmaceutical literacy can be considered as one of the most important components of health literacy in general. At the moment, there is no unified methodology for improving pharmaceutical literacy of individuals and society as a whole. The purpose of the study. Development of a scientific and practical approach to the organization of pharmaceutical education of the adult population with the participation of pharmaceutical specialists. Material and methods. Content analysis, logical analysis, systematization method, modeling method. Results. The components of the theoretical basis for the formation of pharmaceutical competence of the adult population are determined. The differentiation of information about drugs has been carried out, the types of pharmaceutical information have been identified and their subject content has been formed for the purposes of pharmaceutical education of the population. Socio-demographic groups and factors correlating with a higher level of pharmaceutical literacy have been identified. Additional conditions are formulated that should be taken into account in the development of pharmaceutical literacy and the formation of pharmaceutical competence of the adult population. Organizational technologies relevant to the goals of pharmaceutical education have been identified and systematized. The key positions of effective pharmaceutical education practice have been identified. Potential mechanisms for the organization of pharmaceutical education are presented, taking into account the realization of the professional potential of pharmaceutical workers. A multilevel model for the formation of pharmaceutical competence of the adult population has been developed. Conclusion. The proposed methodology for the gradual formation of pharmaceutical competence of the adult population based on the relevant choice of organizational technologies and rules of andragogy, based on the international concept of health education and existing levels of public health, acts as a scientific and practical approach to the formation of an adequate level of pharmaceutical knowledge for the effective and safe use of medicines and the formation of a culture of responsible attitude of citizens to their own health.
Evaluation of the effectiveness of immunoglobulins in treatment of infectious diseases
Authors: Igityan T. , Burgasova O. , Generalova L.
Published: March 2024

Human Specific Hyperimmune Globulins (HIG) are dosage forms of the concentrated purified protein fraction of immunoglobulin G against a specific viral or bacterial antigen. Effective and safe methods of the antibody’s purification makes possible to consider HIG as a preventive and curative agent, for the viral infections, against which there is no specific preventive or antiviral therapy, as well as bacterial infectious diseases due to increasing resistance to antibacterial drugs, especially in persons with immunodeficiencies.