bluuebunny/crossref_metadata_2025 huggingface dataset:
Propuesta de una escala de medida de innovación en el comercio orientada a la sostenibilidad
Authors: Marín-García Antonio , Gil-Saura Irene , Ruiz-Molina María Eugenia , Berenguer-Contri Gloria
Published: October 2024

This study aimed to propose a scale for assessing the concept of innovation in commerce oriented toward sustainability focusing on consumer perspectives. To achieve this objective, an exploratory-descriptive quantitative research was conducted on a sample of 510 customers of general food retail stores. Based on a principal component analysis, a multidimensional measure emerges, comprising six factors: three referring to innovation and three linked to sustainability, affirming the validity of the concept. This highlights the significance of selecting the appropriate elements of innovation and sustainability that retailers should collectively consider to achieve the multiplicative effects suggested by this concept.
Determinants of non-financial information accountability in universities: The case of Colombia
Authors: Ceballos-García Daniel , Calad-Arias Catherine , Correa-García Jaime Andrés
Published: October 2024

This work aims to analyze the determinants of accountability in public and private Colombian universities. The variables access and availability of information were measured through an index and related to variables of the university core missions. Based on legitimacy and stakeholder theory, which proposes a multi-agent approach to the use of information, and given the growing inclusion of Sustainable Development Goals as benchmarks to define the strategies developed by universities, it has been established that university information should look beyond financial aspects and consider environmental and social elements. A panel data methodology was used and 141 observations were made during the 2016-2018 period. The results show a positive relationship among university’s core missions, welfare, and the disclosure of non-financial information. Nevertheless, reporting this information is still an emerging issue, that is, accountability processes need to be strengthened with solid and homogeneous structures to meet the needs of the university community.
Conectividad entre la volatilidad del mercado bonos verdes y no verdes con los mercados internacionales
Authors: Gálvez-Gamboa Francisco , Muñoz-Henríquez Erik , Sánchez-Dávila Elmer
Published: October 2024

This research paper analyzes the spillover effects of volatility between the U. S. green and non-green bond markets with international market volatility between 2018 and 2023. The empirical work used time and frequency domain methodology to analyze the connectivity in the short, medium, and long term. The results demonstrate that both green and non-green bond markets are recipients of volatility, although green bonds receive volatility to a lesser extent than traditional bonds. Despite this, traditional bonds become recipients of volatility during periods such as the COVID-19 pandemic, while green bonds experience volatility reception during the Russia-Ukraine conflict period.
Desarrollo sostenible: un análisis desde el sector de alimentos y bebidas
Authors: Salazar Duque Diego , Santamaría Guido
Published: October 2024

This article aimed to understand the operational activities that gastronomic companies consider in the economic, social, and environmental spheres within the framework of sustainable development. Through a study methodology of non-experimental design, with a quantitative approach of exploratory, descriptive and cross-sectional level, and a data collection technique based on the survey, the correlation between three dimensions and 35 indicators was analyzed. The results showed that there is a greater awareness on the part of companies about social and economic principles than environmental ones; 21 indicators do not significantly align with the proposed model, and the variables of sustainable development can act as partial and total mediators among them. It is concluded that companies must consider the principles of sustainable development of each dimension, based on good business practices, to achieve a balanced model.
Transformación estratégica de una empresa tradicional a una ambidiestra en entornos turbulentos. El caso de Corpaul
Authors: Sánchez Alzate Viviana , Vélez-Ocampo Juan
Published: October 2024

In an ever-changing competitive environment, companies must adapt and respond quickly to market fluctuations. In this process, some companies manage to strengthen their competitive advantage by balancing exploration and exploitation activities. Using case study methodology, this research aimed to understand how a traditional company becomes ambidextrous and strengthens its competitive advantage operating in a turbulent environment. The findings indicate that the company balances the exploration of new opportunities with the exploitation of existing ones, promoting sustainability and forging strategic alliances. Key lessons for companies in transformation processes include the importance of strategic collaborations and reconnecting with their original purpose to identify new opportunities and competitive advantages.
Women as leaders: unpacking the perceptions of gender, trust, and organizational performance
Authors: Reisdorf Carri A. , Lehnert Kevin , Sánchez Carol M.
Published: October 2024

The purpose of this paper is to explore how gender influences the perceptions of women as leaders, and how those affect the relationship between organizational trust and perceptions of the firm’s performance. Results from Latin America and the United States samples show that the more positive the perception of women leaders, the stronger the relationship between trust and performance. These results are important because they provide additional support for enhancing leadership diversity and increasing trust. In particular, they suggest that firms that build strong organizational trust and create leadership diversity by having more women leaders may be associated with more positive perceptions of organizational performance.
Mulheres no Conselho de Administração e a divulgação de gênero à luz da Teoria do Tokenismo
Authors: Silva Larissa Karoline Souza , Oliveira Marcelle Colares , Rodrigues Junior Manuel Salgueiro , Lozano Garcia Maria Belen
Published: October 2024

The study examined the impact of minority representation, specifically women on corporate boards, on disclosing gender-related Corporate Social Responsibility (CSR) information. Data from 2,199 companies across 52 countries during 2010-2017 were analyzed. Using the Tukey-Kramer Post-Hoc test and pooled OLS regressions, the study revealed that a significant female presence positively influences gender-related CSR disclosure when it reaches a certain threshold. Conversely, in boards with low female representation, CSR disclosure is limited. The study contributes by discussing the importance of the presence of minority groups on the board of directors, relying on the Tokenism Theory. Furthermore, it supports the improvement of public policies for minorities and encourages conduct that seeks equal representation of women on boards.
Kombinált epilepszia generalizált és fokális rohamokkal
Authors: Clemens Béla , Dömötör Johanna
Published: October 2024

Háttér és cél – Kombinált (generalizált és fokális rohamokkal járó) epilepsziák irodalmának áttekintése, saját betegeink ismertetése, csoportszintű elemzés. Kérdésfeltevés: csoportszinten melyek a kombinált epilepszia csoport sajátságai és miben különböznek ezek a generalizált és a fokális epilepsziáktól? Módszerek – A vizsgálatba az epilepsziaadatbázisunkból kigyűjtött, 31 kombinált epilepsziás beteget vontuk be. Az esetismertetésekben betegeink klinikai, EEG- és képalkotó vizsgálatokból nyert adatait táblázatba foglaltuk. A betegcsoportot a következőkkel jellemeztük: epidemiológia, a generalizált és fokális rohamok jelentkezésének ideje és sorrendje, a családi anamnézis; a fenotípus súlyosságát összehasonlítottuk adatbázisunk generalizált epilepszia és fokális epilepszia csoportjaival. A statisztikai elemzés kétoldalas Fisher-teszt, Kruskal–Wallis- és post-hoc Dunn-tesztek segítségével történt. Eredmények – Az összes, osztályozható epilepszia 1,56%-a volt kombinált epilepszia. A nők aránya (67,7%) felülmúlta a férfiakét (32,3%). Statisztikailag szignifikáns asszociáció mutatkozott egyrészt a „kis időkülönbség” csoport (amelyben a generalizált és fokális rohamok közel egy időben jelentkeztek) és az egyéb, agyi rendellenességre utaló adatok hiánya között, másrészt a „nagy időkülönbség” csoport (amelyben a két rohamtípus jelentkezése között 4–37 év telt el) és egyéb, agyi rendellenesség jelenléte között (p = 0,02). Pozitív családi anamnézisű betegek gyakoribbak voltak a kombinált epilepszia csoportban, mint a generalizált epilepszia csoportban (p = 0,03) és a fokális epilepszia csoportban (p < 0,0001). Az absence rohamok elektroklinikai fenotípusa több atípusos vonást mutatott kombinált epilepsziában, mint a generalizált epilepsziához tartozó absence epilepsziákban (p < 0,0001). Következtetés – A „kis időkülönbség” és „nagy időkülönbség” betegek megkülönböztetésének patogenetikai és gyakorlati jelentősége van. A kombinált epilepsziák genetikus meghatározottsága felülmúlja a másik két nagy epilepsziatípusét.
Cytochromes P450 as Tools for Electroenzymatic Synthesis
Authors: Koroleva P.I. , Gilep A.A. , Shumyantseva V.V.
Published: October 2024

The electrocatalytic properties of cytochrome P450 2C9 and the cytochrome P450 2C9/FAD and cytochrome P450 2C9/FMN complexes have been studied using a two-electrode system. The system consisted of an enzymatic catalyst electrode modified by the membrane-like compound didodecyldimethylammonium bromide (SPE/DDAB) and a measuring electrode, modified with carbon nanotubes (SPE/CNT). To study the effectiveness of electroenzymatic reactions catalyzed by cytochrome P450 2C9, the nonsteroidal anti-inflammatory drug diclofenac was used as a substrate. Cytochrome P450 2C9 catalyzes the stereospecific hydroxylation reaction to form 4′-hydroxydiclofenac. The metabolite 4′-hydroxydiclofenac was recorded at a potential E=+0.12 (relative to Ag/AgCl).The use of FAD and FMN as low-molecular mediators made it possible to increase the efficiency of electrocatalysis of the SPE/DDAB/CYP2C9/FAD system to 148±10% and SPE/DDAB/CYP2C9/FMN to 113±6% compared to SPE/DDAB/CYP2C9 (100±5%), and also increase the rate of the enzymatic reaction by 1.5 and 1.13 times, respectively.
Prediction of Peptide Ion Distribution in Positive Electrospray Ionization
Authors: Voronina A.I. , Skvortsov V.S.
Published: October 2024

We have investigated the possibility of predicting the distribution of ions of different charge during electrospray ionization of peptides in mass spectrometric experiments using neural networks. Three independent data sets obtained on the same equipment and deposited in ProteomeXchange (PXD032141, PXD051750, PXD019263) were used as training and test samples. A set of fractional values for 1+ to 5+ ions was calculated as predicted values for each of the newly identified peptides. Four different sets of peptide descriptions were used as independent variables, including both the spectrum of amino acid residues and the physicochemical properties of the amino acid residues. Sixty-four variants of neural networks were analyzed, varying the input description, number and type of layers, activation and loss functions. The coefficient of determination and a set of Euclidean, Sørensen, Chebyshev, and Cosine metrics were considered as measures of prediction quality. For the best selected variants, the error did not exceed 10% in 80% of the cases. This accuracy may be sufficient for a preliminary estimation of the probability of detecting a peptide ion of a given charge.
Cuatro sueños más
Authors: Alfaro Olmedilla Juan José
Published: October 2024

Sueño, magia e ilusión son palabras que siempre deberían acompañar al teatro. Son sus sinónimos, por decirlo de alguna manera. En estos “Cuatro sueños más” la magia, la ilusión y los sueños os llevarán hasta el Olimpo y la construcción de Europa; a la inocencia de la infancia de la mano de un Principito muy especial; a lo absurdo del enfrentamiento y el insulto inútil con los encontronazos entre las familias de Romeo y Julieta; y a las enseñanzas y moralejas de unos cuentos muy muy antiguos pero que, sorprendentemente, sirven también para aconsejar sobre los peligros de las nuevas tecnologías. Dejaos llevar, por lo tanto, por los sueños, la magia y la ilusión… por el Teatro.
Deepening connections with people and place
Authors: Lees Jacqui
Published: October 2024

This article draws from a Teaching and Learning Research Initiative research project that aimed to explore how three early childhood centres support children to experience and learn about their local area, including its stories, geology, biodiversity, and cultural meanings. The project helps children envision socioecological futures. This article focuses on one of the research settings that participated in this study, Pakuranga Baptist Kindergarten, and how the pedagogy of listening and an unhurried approach to learning supports children to deepen both their understandings of and connection to place.
Pragmatic Functions of Discourse Particles in Lutsotso conversations
Authors: Ongolo Joel , Mudogo Benard , Barasa David
Published: October 2024

The study of the functions of discourse particles in the African languages has received much attention from various scholars, although not from a pragmatic perspective. A good understanding of the pragmatic functions of discourse particles in African languages can benefit language users. However, limited knowledge in this field has affected communication of ideas more clearly and concisely. This paper explores the pragmatic functions of these discourse particles in Lutsotso conversations within the Relevance Theory (RT) structure by Sperber and Wilson (1995). A combined method of native speakers’ intuition and data extraction from Lutsotso conversations were used to collect data. After that, a descriptive research design was used to analyze the collected data. The findings revealed that in Lutsotso conversations, discourse particles play the following pragmatic functions depending on the context: cutting in politely, initiating a new topic, highlighting of a hypothesis that immediately follows, capturing the attention of the listeners, holding the flow and keeping one’s turn, and disagreeing politely.
Creating Capacity for Digital Transformation of Education:
Authors: Cui Hongran , Irvine Valerie , Miller Mariel , Madland Colin
Published: October 2024

Educational institutions and training programs have faced an accelerated transformation toward the integration of technology. However, it is unclear whether the capacity to train qualified personnel to support this digital transformation in education. In this session, we review university websites across Canada looking at the availability of online PhD programs in Education Technology. Findings indicate only one is offered online only (5% or 1 out of 20) and two provide students with the possibility to study in a blended format for their PhD program, which is 10% (2 out of 20) of all Canadian universities that have PhD programs. Only 5% (1 out of 20) of Canadian institutions provide a PhD program in educational technology; however, this is offered on campus only. While this review excludes the EdD pathway, we did find two EdD programs in educational technology that could be accessed entirely online and one blended program. As technological and conceptual shifts of entire sectors that prioritize digital learning and digital literacy (e.g., B.C. Digital Learning Strategy), there is significant demand for PhD qualified individuals to lead or execute these initiatives. As such, there needs to be more discussion about how to make PhD study more accessible, specifically in educational technology.
Сучаснi екологiчнi пiдходи до переробки рибних вiдходiв рибного господарства України
Authors: Глушко Юлія , Нагорнюк Тетяна , Савенко Неля , Гаркава Катерина
Published: October 2024

Метою дослiдження було проаналiзувати основнi сучаснi екологiчнi пiдходи до переробки рибних вiдходiв та рiвень їх впровадження в свiтовiй та вiтчизнянiй аквакультурi.
OTDK-RA SZOCIALIZÁLÓ KONFERENCIA HALLGATÓKNAK – 2018 (ÖSSZEFOGLALÓ)
Authors: EKE
Published: October 2024

Summary
„NŐ AZ ESÉLY!”
Authors: Tóth Ilona , Kormos Dénes
Published: October 2024

The "NŐ az esély!" entitled talent development program was realized by the Hungarian EDU-MÉD PLUSZ Ltd. in the years 2019-2020 with supporting of the National Talent Development Program. Note: this title has two meanings: "Woman is the chance" and "Chance is increasing". The goal of this project was to help the chance equalization of schoolgirls in the area of maths, informatics, and natural science.
A „HÖLGYEK A TUDOMÁNYBAN 2020/2021” PROJEKT
Authors: Mező Katalin , Mező Lilla Dóra
Published: October 2024

Workshop Report on the “Ladies in Science 2020/2021” project.
MRI-Based Brain Tumor Instance Segmentation Using Mask R-CNN
Authors: Nasrudin Muhammad
Published: October 2024

Brain tumor segmentation is a crucial step in medical image analysis for the accurate diagnosis and treatment of patients. Traditional methods for tumor segmentation often require extensive manual effort and are prone to variability. In this study, we propose an automated approach for brain tumor segmentation using Mask R-CNN, a state-of-the-art deep learning model for instance segmentation. Our method leverages MRI images to identify and delineate brain tumors with high precision. We trained the Mask R-CNN model on a dataset of annotated MRI images and evaluated its performance using the mean Average Precision (mAP) metric. The results demonstrate that our model achieves a high mAP of 90.3%, indicating its effectiveness in accurately segmenting brain tumors. This automated approach not only reduces the manual effort required for tumor segmentation but also provides consistent and reliable results, potentially improving clinical outcomes.
Peracute Enterotoxemia in Saanen and Alpine Goat Herd
Authors: Esmaeili Hossein , Joghataei Seyed Mehdi
Published: October 2024

Background: Enterotoxemia" or "overeating disease" is considered a common and often fatal disease affecting the economy of small ruminant breeding systems. This study presents findings on the occurrence of a peracute form of enterotoxemia in a herd of Saanen and Alpine, including an examination of the clinical signs, post-mortem findings, and methods for diagnosis.
examination of the clinical signs, post-mortem findings, and methods for diagnosis. Methods: In a herd of goats a distressing situation occurred where the goats displayed signs (Sudden death and high fever) of peracute enterotoxemia (125 kids). It is noteworthy that these goats had previously been vaccinated against enterotoxemia. The onset of the condition seemed to be linked to three instances of interruption and reconnection of concentrate feed. To obtain a definitive diagnosis, the findings from postmortem examinations and ELISA were utilized.
Results: In total, 60 Alpine and 65 Saanen succumbed to this peracute form. These losses occurred over three days but were successfully stopped by re-vaccination after two days. Clinical signs, postmortem observations, bacterial analysis, and ELISA results all provided confirmation of enterotoxemia. Notable findings included high fever (90%), duodenum hyperemia (89%), pulmonary edema (82%), convulsions (43%), and hemorrhage in the pericardium and endocardium (58%).
Conclusion: Frequent and consecutive changes in goats' diet or discontinuation of concentrate supply by breeders can disrupt the vaccine-induced immune barrier, increasing the likelihood of enterotoxemia, and leading to casualties and economic losses. Consistent and stable nutrition practices are essential for maintaining vaccination efficacy and preventing enterotoxemia in goats, particularly kids.
Antibiotic Therapy in Asthma as One of First Step Treatment, a Phase 3 Randomized Clinical Trial
Authors: Nejati Sara , Mirsadraee Majid , Ghaffari Shadi
Published: October 2024

Background: Focus of this study was on subjects suffering from new onset asthma, but actually, they may involve with an infection. Objectives: The target of this study was to determine the frequency of total control of asthma in new onset asthma.
Methods: this is a phase 3 randomized clinical trial. The participants were 50 new onset asthma, who feel suffering from respiratory infection, however the physician diagnosis was asthma according to wheezy chest, spirometry and clear chest roentgenogram. Age less than 18 years and pregnant women were excluded. The subjects were randomly divided into two groups, doxycycline hyclate and the placebo arms. The drugs were repacked in similar in shape container. Primary endpoint was time to first recurrence. Secondary endpoints were frequency of total control of asthma, dyspnea, cough, asthma control test (ACT) score, FEV1, FEV1/FVC, eosinophil and neutrophil in blood and sputum.
Results: The difference of clinical findings between two groups before the trial were not significant. Ten percent reported acute attack of asthma during last two months. Treatment with Doxycyline revealed significant improvement of clinical findings, asthma attack and ACT score after two months of treatment, however, complete resolution of clinical findings were significantly higher in Doxycyline group compare to placebo. Clinical findings and FEV1 percent predicted in Doxycyline group T2low asthma group showed significant improvement which were not depicted in T2high group. Eighteen months follow up of the subjects showed complete resolution of asthma symptoms in 12 (48%) on Doxycyline group, which was significantly higher than control group (5 (20%). Time to first exacerbation in doxycycline group was 13.6±5.64 months which was significantly longer than control group (7.49±6.95, P=0.002). Time to first exacerbation in CRP positive was significantly longer (13.64±5.35 months) than CRP negative subjects (9.67±7.76 months, P=0.02).
Conclusion: Doxycycline is an effective antibiotic for preventing recurrence of asthma, in selected new subjects who suspicious for respiratory infection.
In the Memory of Nikolay F. Murashov
Authors:   Leading Research Scientist of the Center of Criminal and Criminal Procedure Law of the Institute of Legislation and Comparative Law under the Government of the Russian Federation, Fedorov Aleksandr V. , Mikhaylov Valentin I. ,   Chief Research Scientist of the Center for Criminal and Criminal Procedure Law of the Institute of Legislation and Comparative Law under the Government of the Russian Federation
Published: October 2024

The article is dedicated to the memory of Nikolai Fedorovich Murashov, a famous scientist and the oldest author of the Drug Control magazine.
Social Media Virality: Reaching the Tipping Point
Authors: Bhimani Alnoor , Zainulabdin Khawaja , Ali Khudejah , Ali Muqtadir Syed , Hausken Kjell
Published: October 2024

Social media virality has become a key factor in determining how far to extend social media marketing and digital promotion campaigns. The point at which content transitions to viral spread underpins promotion-level decisions. We employ a logistic equation to identify tipping point decisions for viral content online promotions in given contexts. We consider case studies indicative of viral content on social media following a traditional S-curve when examined in a single domain. Our study contributes to understanding the decision mechanics of reaching a tipping point in a manner that reflects the concerns of digital marketers and online marketing strategies generally. We also see our approach to determining this point as furthering social media research in an area of growing importance and assessing how viral content can be managed.
Impact of RNA Enzymes and RNA Protein Complexes in Unleashing RNAInterference for Manyfold Crop Improvements: A Review
Authors: Abajebal Nezif , Barnabas John , Abebe Tsegaye
Published: October 2024

RNA interference, which enables more accurate downregulation of gene expression without interfering with the expression of various genes, is a beneficial instrument for gene silencing and a potential gene regulatory strategy in functional genomics that has a big impact on crop progress. Small interfering RNA molecules swift up the RNAi gene silencing machinery, effectually suppressing a target gene. Subsequently transgene proteins not present from genetically modified RNAi plants, it has a sum of rewards over orthodox transgenic methods. Dicer, Drosha which are RNA enzymes, along with protein complexes, RISC and Argonaute, institute at the epicenter of this technology. These explicit RNA binding proteins and ribonucleases regulate the synthesis and production of tiny regulating RNAs. Several latent usages for this ground-breaking process in agriculture have been identified for improving crops, such as the construction of disease-resistant, biotic or abiotic, high-yielding, stress-tolerant and exclusive assortments; enhancement of nutritional quality; removal of allergens and toxins; and postponing the ripening of fruits and vegetables for extended storage periods. This ground-breaking procedure has the latent to be further utilized to pave the way for the creation of environmentally friendly biotech methods for crop protection and enhancement. Improving research and development activities in this auspicious field is imperative to ensure the efficient appropriate and safe application of these instruments as enduring remedies for agricultural enhancement.
Caracterización climática de la lluvia del Pacífico Norte de Costa Rica usando análogos construidos
Authors: Ugalde Kendall , Alfaro Eric J. , Hidalgo Hugo G. , Maldonado Tito
Published: October 2024

Se determina el inicio y término de la estación lluviosa (IELL y TELL respectivamente), además de la duración de la estación seca y lluviosa (DES y DELL respectivamente), con datos de precipitación en rejilla sobre Guanacaste para el periodo 1950-2020 conformado por el acople de dos conjuntos de datos, el primero es el conjunto Climate Hazards group Infrared Precipitation with Stations (CHIRPS) y el segundo siendo el reanálisis ERA5 al que se le aplicó un ajuste de escala para extender la cobertura temporal de los datos de CHIRPS. Se caracterizó su IELL, TELL, DELL y DES con estadísticos como la mediana, desviación estándar, rango inter cuartil y tendencias. Además, se relacionaron con fuentes de variabilidad climática como El Niño-Oscilación del Sur (ENOS), la temperatura superficial del océano Atlántico Tropical Norte (ATN) y la corriente en chorro de bajo nivel del Caribe (CLLJ, por sus siglas en inglés). Los datos representan adecuadamente la climatología del IELL, TELL, DELL, DES y las precipitaciones de la región, además de capturar la variabilidad asociada a la CLLJ y al acople de los océanos (ATN-ENOS), pero no la asociada al ATN y ENOS individualmente. Aunque no se pudo determinar si esto se debe a los datos de ERA5 o al método de reducción de escala usado, por lo que se recomienda verificar si ERA5 captura tal variabilidad oceánica al realizar el mismo análisis en un periodo de tiempo de 1980-2020 donde se tiene mayor disponibilidad de observaciones como estaciones meteorológicas o CHIRPS que ya ha sido validada.
Alergia al Ácido Acetilsalicílico (AAS) en el contexto de AINEs: navegando desde una perspectiva inmunitaria
Authors: Barrantes-Alvarado Reychell , Coronado-Salazar Julyana , Díaz-Méndez Donalld , Monge-Brenes Andrés , Salas-Campos Alison
Published: October 2024

Los antiinflamatorios no esteroideos (AINEs) se utilizan en todo el mundo para tratar el dolor y la inflamación; sin embargo, pueden desencadenar varios tipos de reacciones de hipersensibilidad a fármacos en todos los grupos de edad. Un número significativo de reacciones de hipersensibilidad a los AINEs se deben a mecanismos inmunológicos. Con el fin de proporcionar una base que permita una mejor comprensión y gestión médica a la alergia al ácido acetilsalicílico (AAS) en el contexto de antiinflamatorio no esteroide (AINEs), este articulo tiene el propósito de revisar los principales aspectos relativos a las causas, mecanismo inmunológico, síntomas, diagnóstico y opciones de tratamiento relacionados con esta alergia. Los AINEs se clasifican según su estructura química y su selectividad para inhibir las enzimas COX. Se resaltan las ventajas de los AINEs selectivos de COX-2 al minimizar los efectos secundarios gastrointestinales, y se destaca el AAS como un fármaco comúnmente recetado debido a su actividad multifuncional, incluida la prevención del accidente cerebrovascular y el infarto de miocardio.
Imemes
Authors: Bitonte María Elena
Published: October 2024

El presente artículo explora los principios que sustentan el análisis sociosemiótico de los imemes –o memes de Internet–, ejemplares típicos de la producción de sentido en la contemporaneidad. El encuadre sociosemiótico de los imemes se aparta de otros abordajes signados por el evolucionismo biológico y plantea una perspectiva anti-determinista y dinámica, cuya principal premisa ubica los fenómenos sociales en relación con sus condiciones de producción, circulación y reconocimiento. Siguiendo esta perspectiva analítica, los imemes conforman una clase de fenómenos mediáticos que se distingue de otros por su particular forma de circulación: la proliferación. De ahí la importancia de diferenciar la memética –como modo de producción de sentido– de la viralidad. Desde esta aproximación, los actores sociales no son vistos como vectores de transmisión cultural ni los imemes como imágenes que imitan un original, sino como interpretantes de los fenómenos sociales que toman como objeto, a la vez que productores de memoria y de contacto social. ¿Cuáles son las condiciones de propagación de los imemes? El artículo procura una explicación posible a través del análisis de sus condiciones de producción, circulación y reconocimiento y sugiere una vía de indagación sobre la índole autopoiética de los imemes.
URBANIZATION AS AN INDICATOR OF DEVELOPMENT OF INDIA: AN INTROSPECTIVE STUDY THROUGH GINI CONCENTRATION
Authors: Mandal Ram Krishna
Published: October 2024

Introduction: Development and urbanisation are closely related, there isn't a clear-cut relationship between the two. The process of urbanization can be measured in terms of many demographic dimensions. Objective: The paper aims to calculate the Gini Concentration Ratio (GCR) of urban population i.e., Co-efficient of urban concentration for the urban towns in India for 2001 and 2011 censuses to examine whether urban concentration increases or not leading to urbanization. Method: This study is an introspective type of research based on secondary data gathered from books, articles, websites, web-based journals, Census Reports, and government offices. Result and Discussion: Gini-Concentration Ratio is used to calculate for 2001 and 2011 censuses and its different values are interpreted. Findings: The value of Gini concentration ratio of 2011 census is greater than 2001 census indicating that the concentration of urban population is increasing thereby development of India. Conclusion: An important way to reduce the differences in the rate of urbanisation between rural and urban areas is seemed to prioritise for socio-economic development of the country.
A Study on Crime against Scheduled Castes in Metropolitan Cities in India
Authors: Sarkar Sukanta
Published: October 2024

The paper discussed crime against scheduled castes in metropolitan cities in India. It has found that higher incidences of crime against scheduled tribes identified in Lucknow, Kanpur, Jaipur and Bengaluru. On the other hand, least number of crimes are recorded in Coimbatore, Kochi, Chennai, Kozhikode and Surat. Incidences of murder, attempt to commit murder, assault on women with intent to outrage her modesty, assault on women above 18 years, and assault or use of criminal force on women with intent to disrobe crime are highest recorded in Bengaluru. Highest incidences of stalking crime are reported in Indore. Highest incidences and victims of sexual harassment, and insult to the modesty of women is reported in Hyderabad. Highest incidences and victims of simple hurt and grievous hurt are logged in Patna. Highest incidences of assault of children, rape, rape of women above 18 years, and attempt to commit rape are reported in Ahmedabad, Indore and Jaipur Kanpur has the highest incidences and victims of kidnapping and abduction against scheduled castes. Therefore, city corporations should implement policies and laws for minimizing crimes against scheduled castes and there should be proper awareness programs of such crimes.
Catalina Bravo en la escena madrileña y catalana del siglo XIX
Authors: Barba Dávalos Marina
Published: October 2024

Este artículo presenta una aproximación biográfica a la figura de Catalina Bravo, una actriz relegada al olvido. Recorre su trayectoria artística en los principales teatros madrileños, Príncipe y de la Cruz, y en el Teatre de la Santa Creu de Barcelona, destacando el repertorio que interpretó, su evolución en la jerarquía de actrices y su reflejo retributivo, así como la recepción de su trabajo por la crítica. Recientemente se ha conocido que la actriz interpretó la única intervención musical del drama de Hartzenbusch Los amantes de Teruel. Se pretende, desde esta investigación, recuperar la trayectoria escénica de Catalina Bravo prestando atención a su vertiente musical para poder discernir si la actuación en el drama de Hartzenbusch fue anecdótica o si su repertorio acredita que pueda ser considerada una canta-actriz, de la misma manera que sus coetáneas Matilde Díez o Bárbara Lamadrid.
Los populismos historiográficos en el nacionalismo español
Authors: Tébar Gómez José
Published: October 2024

Desde el cambio de milenio, han proliferado en España y otros países de su entorno una serie de discursos históricos producidos por personas ajenas a la disciplina histórica con el objetivo de reivindicar un pasado nacional perdido mientras se ataca a la historiografía académica por haberlo desestimado. Estos populismos historiográficos se han convertido en un producto de masas gracias a la aparición de numerosos ensayos, documentales, series, películas y al auge de las redes sociales, terrenos en los que se divulga continuamente acerca del pasado, las más de las veces con fines interesados y sin tener en cuenta el conocimiento histórico producido por los historiadores. En las páginas siguientes trataré de analizar el surgimiento de estos discursos pseudohistoriográficos, sus causas y qué repercusiones tienen tanto en la sociedad y la política como dentro del colectivo de historiadores.
Sánchez-Albornoz, the Danger of the Fitna, and the Problem of Spanish Unity and History
Authors: Albarrán Javier
Published: October 2024

This article focuses on the almost unknown novel Ben Ammar de Sevilla. Una tragedia en la España de los taifas, written by the famous medievalist Claudio Sánchez-Albornoz (d. 1984), who while paradoxically contributing greatly for the knowledge on the Muslim Iberia and its historiography, at the same time consolidated the 19th century discourses of the Reconquista and the «Hispanized» al-Andalus. The aim of this article is to study, on the one hand, how al-Andalus is depicted on Sánchez-Albornoz’s novel, and, on the other, to interpret why he wrote this book and how it blends with his general way of thinking the history of Spain and his own present. The paper argues that this novel must be read through Sánchez-Albornoz’s experience of civil war and exile, in which the problem of the unity of the Spanish people throughout its history becomes crucial in his historical thought. The Taifa period, in which the novel focuses, and the consequences of the fitna and disintegration of the Andalusi unity, are a mirror in which Sánchez-Albornoz reflects his own reality and his patriotic longings. Thus, the main characters of his novel, such as the exiled king of Seville al-Mu‘tamid, become (in)direct parallels of the author’s life. Ideas such as that of the homo hispanus, the concern for union and the avoidance of the fitna are fundamental for a global understanding of Sánchez-Albornoz’s historical proposal. These perspectives can explain the apparent contradictions in his approach on the history of al-Andalus, and can also explain how the Middle Ages consisted of a way to address his own present.
The Effect of Globalization on Hemoglobinopathies and its Genetic Inheritance: The Booster Effect of Genetic Combinations
Authors: Guerreiro Ferreira Catarina , Lima Ana Filipa , Sitari Adelina , Ferrão Anabela , Rocha Elsa
Published: October 2024

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How Can We Improve Care for Patients with Atopic Dermatitis in Portugal?
Authors: Torres Tiago
Published: October 2024

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Pengembangan Biskuit Canavalia Kaya Protein Berbahan Dasar Tepung Kacang Koro Pedang terhadap Daya Terima dan Kandungan Zat Gizi sebagai Makanan Tambahan Ibu Hamil untuk Pencegahan Stunting
Authors: Septiani Baiq Dewi Sukma , Ardiansyah Lalu Dwi Satria
Published: October 2024

Latar Belakang: Salah satu upaya mengatasi masalah stunting pada balita khususnya di Kabupaten Lombok Tengah adalah dengan memperbaiki status gizi ibu selama masa kehamilan terutama ibu dengan kondisi Kurang Energi Kronis (KEK). Program Pemberian Makanan Tambahan (PMT) bagi ibu hamil telah diatur dalam Peraturan Menteri Kesehatan Nomor 51 Tahun 2016 dimana ibu hamil dengan kondisi KEK diberikan program perbaikan gizi yang telah ditetapkan oleh pemerintah yaitu dengan PMT berupa biskuit.
Tujuan: Melakukan pengembangan produk makanan tambahan bagi ibu hamil berupa biskuit dengan pemanfaatan bahan pangan lokal bersumber kacang koro pedang.
Metode: Rancangan penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan 3 kali perlakuan (K=3), 1 unit percobaan dan dilakukan 3 kali pengulangan, sehingga total jumlah percobaan adalah 3×1×3=9. Dilakukan pula penambahan tepung kacang koro pedang pada produk Biskuit Canavalia dengan takaran yang berbeda, kemudian hasil yang dianalisis meliputi uji daya terima dan kandungan zat gizi diantaranya energi, protein, lemak, karbohidrat serta kalsium.
Hasil: Hasil penelitian menunjukkan penambahan tepung kacang koro pedang sebanyak 50 g meningkatkan daya terima responden dari segi warna, aroma, tekstur, dan rasa. Penambahan tepung kacang koro pedang 50 g pada produk Biskuit Canavalia meningkatkan kandungan gizi diantaranya energi, protein, lemak, karbohidrat serta kalsium. Kandungan zat gizi Biskuit Canavalia terbaik pada kelompok penambahan tepung kacang koro pedang 50 g meliputi energi 479 kkal, protein 26 g, lemak 21,82 g, karbohidrat 76,66 g serta kalsium 59,70 mg.
Kesimpulan: Proporsi penambahan tepung kacang koro berpengaruh terhadap daya terima dan peningkatan kandungan zat gizi Biskuit Canavalia meliputi warna, aroma, tekstur, dan rasa.
Analisis Kandungan Asam Fitat dan Tanin Nasi dari Beras Analog Berbasis Pangan Lokal sebagai Alternatif Pangan Fungsional
Authors: Rahmawati Sri , Sabta Aji Arif , Saloko Satrijo , Aprilia Veriani , S. Djidin Radhiyya Tsabitah , Sailendra Nova Veronika , Khoirunnisah Frisqi Meilany
Published: October 2024

Latar Belakang: Beras analog sebagai salah satu alternatif diversifikasi pangan yang memiliki karakteristik mirip nasi dari beras padi. Oleh karena itu, aneka ragam bahan pembuat beras analog dapat berpotensi menjadikan produk ini sebagai salah satu pangan fungsional yang memiliki manfaat kesehatan.
Tujuan: Untuk melihat efek dari teknik penanakan dengan kandungan asam fitat dan tanin nasi beras analog (sorgum, mocaf, glukomanan, dan tepung kelor) dan nasi beras padi C4.
Metode: Penelitian desain eksperimen yang menggunakan RAL sebanyak dua perlakuan yaitu penanakan beras dengan kukusan dan rice cooker. Penelitian dilakukan pada Oktober-November 2022 di Laboratorium Chem-mix Pratama. Dua sampel terdiri dari beras analog dan beras padi (Tipe C4) dilihat kandungan zat asam fitat dan tanin menggunakan metode Sfektofotometri Infra-Red dan Sfektrofotometri UV-S.
Hasil: Kandungan asam fitat tertinggi nasi beras analog metode pemasakan rice cooker dan kukusan adalah 6,64 mg dan 4,75 mg. Rata-rata kandungan tanin tertinggi nasi dari beras analog dengan metode pemasakan rice cooker dan kukusan adalah 18,35 mg dan 19,55 mg. Kandungan asam fitat tertinggi nasi dari beras padi C4 dengan dengan metode pemasakan rice cooker dan kukusan adalah 7,43 mg dan 9,01 mg. Kandungan tanin nasi dari beras padi C4 dengan dengan metode pemasakan rice cooker dan kukusan adalah 4,45 mg dan 9,11 mg.
Kesimpulan: Kandungan asam fitat nasi dari beras analog lebih rendah daripada beras padi C4. Kandungan tanin nasi dari beras analog lebih tinggi daripada beras padi C4. Penelitian lebih lanjut perlu dilakukan untuk menurunkan kandungan tanin beras analog.
Virtual Posyandu Program during the Pandemic Maintained Children’s Growth and Development
Authors: Marchianti Ancah Caesarina Novi , Rachmawati Dwita Aryadina , Kusuma Irawan Fajar , Sudarmanto Yohanes
Published: October 2024

Background: Posyandu program suspension due to COVID-19 has resulted in a decrease in monitoring children’s growth, leading to undetected problems. Understanding mothers' eating behavior plays a crucial role in preventing malnutrition, we must continue the program as a health promotion medium to enhance mothers' understanding and track children's growth and development.
Objectives: This research aimed to determine the effectiveness of virtual Posyandu program in strengthening cadre health promotion services for nutritionally vulnerable children in Jember Regency agricultural area during the absence of offline Posyandu.
Methods: The research was carried out September 2022-January 2023, implementing a 21-day intervention on 169 respondents from Puskesmas Arjasa and Paleran (representing two different socio-cultures). The cadres utilized the application to enhance children's nutritional health and instruct parents on its usage. The success parameter is that there were significant differences between the growth and development of children pre- and post-program. Growth variables were assessed by measuring nutritional status according to Ministry-of-Health Regulation, before and after the intervention, while development variables were assessed using a Developmental Pre-Screening questionnaire (DPSQ).
Results: The virtual Posyandu program in both Puskesmas demonstrated significant differences (p<0.001) in children's growth and development parameters, such as height-for-age, weight-for-height, and DPSQ, between the pre- and post-program periods. Despite the challenges posed by the pandemic, the program has effectively maintained children's growth and development.
Conclusions: Balitagrow© Android-based application in virtual Posyandu program effectively maintained children’s growth and development in pandemic era and worth continuing to be developed according to user needs.
Tinjauan Literatur Terkini: Peranan Konsumsi Teh terhadap Penyakit Hipertensi
Authors: Balatif Ridwan , Lubis Nenni Dwi Aprianti
Published: October 2024

Latar Belakang: Di Indonesia, prevalensi hipertensi mengalami peningkatan dari 25,8% (2013) menjadi 34,1% (2018). Pasien dengan hipertensi diharuskan mengonsumsi obat-obatan anti-hipertensi seumur hidup untuk mengendalikan tekanan darah. Selain terapi farmakologi, teh mengandung senyawa aktif Epigallocatechin-3-gallate (EGCG) yang dapat membantu menurunkan tekanan darah.
Tujuan: Untuk memberikan gambaran senyawa aktif pada teh yang berpotensi menurunkan tekanan darah.
Metode: Artikel ini menggunakan sumber data terkait uji klinis acak terkontrol yang dicari melalui laman Pubmed pada rentang waktu 2017-2022 dengan kata kunci teh, tekanan darah dan hipertensi.
Diskusi: Sebanyak 9 dari 35 artikel diperoleh dari pencarian literatur tersebut. Hasil pencarian menunjukkan EGCG dalam bentuk kapsul dengan rentang dosis 75-300 mg dapat menurunkan tekanan darah secara signifikan. Hal yang sama juga didapati pada studi yang menggunakan kapsul berisi antosianin dan polifenol. Dari 4 studi yang menggunakan minuman teh sebagai bahan intervensi, diperoleh bahwa secara nyata minuman teh dapat menurunkan tekanan darah. Hanya 1 studi yang menyebutkan bahwa minuman teh dapat meningkatkan tekanan darah secara signifikan. Perbedaan hasil ini mungkin dikarenakan adanya perbedaan kadar zat aktif dan adanya kafein dalam teh yang diduga mempengaruhi hasil pengukuran tekanan darah.
Kesimpulan: Uji klinis terkini terkait teh terhadap pengendalian tekanan darah umumnya menggunakan zat aktif yang terdapat pada teh terutama EGCG. Penggunaan kapsul EGCG dalam berbagai uji klinis memberikan gambaran penurunan tekanan darah. Penelitian lanjutan dapat difokuskan untuk pemanfaatan potensi EGCG ini dalam populasi sampel yang lebih besar.
Factors Associated with the Outcomes of Patients with Hospital-Acquired Pneumonia (HAP) at Dr. Moewardi General Hospital, Surakarta
Authors: Nawanindha Natasha , Saptawati Leli , Widyaningsih Vitri
Published: October 2024

Introduction: Hospital-acquired pneumonia (HAP) is a common infection with a poor prognosis. Previous studies on factors influencing HAP outcomes have yielded inconsistent findings. Therefore, further research is needed to determine risk factors that affect HAP outcomes. This study evaluated the factors associated with HAP outcomes to enable timely interventions to reduce mortality, costs, and length of stay (LOS).
Methods: This cross-sectional study was conducted at Dr. Moewardi General Hospital, Surakarta, using medical record data from January to December 2022. The data included age, gender, malnutrition, anemia, level of consciousness, comorbidities, bacterial culture, and multidrug-resistant organisms (MDROs). The analyses were performed using the Chi-squared and Mann-Whitney U tests, followed by multiple logistic and linear regression tests to determine the correlation between risk factors and outcomes (recovery, death, and LOS).
Results: This study included 102 patients with HAP, the majority being males (64.7%) aged 60 years old and above. Additionally, most patients did not exhibit malnutrition (87.3%) or anemia (96.1%), had normal levels of consciousness (67.6%) and mild comorbidities (60.8%), were not infected with MDROs (66.7%), and were predominantly infected by Klebsiella pneumoniae (21.6%). The multiple logistic regression test revealed that decreased consciousness was significantly associated with increased mortality (p < 0.001). Meanwhile, age 60 years old and above was significantly associated with a shorter LOS (p = 0.05).
Conclusion: The majority of HAP cases occurred in men aged 60 years and above. Furthermore, there was a significant relationship between decreased consciousness and increased mortality, as well as between the age of 60 years and above and a shorter LOS.