bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure S9 from The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer
Authors: Mattox Austin K. , Douville Christopher , Wang Yuxuan , Popoli Maria , Ptak Janine , Silliman Natalie , Dobbyn Lisa , Schaefer Joy , Lu Steve , Pearlman Alexander H. , Cohen Joshua D. , Tie Jeanne , Gibbs Peter , Lahouel Kamel , Bettegowda Chetan , Hruban Ralph H. , Tomasetti Cristian , Jiang Peiyong , Chan K.C. Allen , Lo Yuk Ming Dennis , Papadopoulos Nickolas , Kinzler Kenneth W. , Vogelstein Bert
Published: October 2023

Supplemental Figure 9. Plasma AST and ALT levels before and ~24 hours after surgery for pancreatic cancer. AST and ALT levels substantially increased in all five patients.
Supplementary Table 2 from GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
Authors: Tagore Mohita , Hergenreder Emiliano , Perlee Sarah C. , Cruz Nelly M. , Menocal Laura , Suresh Shruthy , Chan Eric , Baron Maayan , Melendez Stephanie , Dave Asim , Chatila Walid K. , Nsengimana Jeremie , Koche Richard P. , Hollmann Travis J. , Ideker Trey , Studer Lorenz , Schietinger Andrea , White Richard M.
Published: October 2023

RNA-seq and GSEA results in switched vs non-switched keratinocytes
Supplementary Table 1 from GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
Authors: Tagore Mohita , Hergenreder Emiliano , Perlee Sarah C. , Cruz Nelly M. , Menocal Laura , Suresh Shruthy , Chan Eric , Baron Maayan , Melendez Stephanie , Dave Asim , Chatila Walid K. , Nsengimana Jeremie , Koche Richard P. , Hollmann Travis J. , Ideker Trey , Studer Lorenz , Schietinger Andrea , White Richard M.
Published: October 2023

LOPAC Screen results in melanoma keratinocyte co-cultures
Figure S4 from The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer
Authors: Mattox Austin K. , Douville Christopher , Wang Yuxuan , Popoli Maria , Ptak Janine , Silliman Natalie , Dobbyn Lisa , Schaefer Joy , Lu Steve , Pearlman Alexander H. , Cohen Joshua D. , Tie Jeanne , Gibbs Peter , Lahouel Kamel , Bettegowda Chetan , Hruban Ralph H. , Tomasetti Cristian , Jiang Peiyong , Chan K.C. Allen , Lo Yuk Ming Dennis , Papadopoulos Nickolas , Kinzler Kenneth W. , Vogelstein Bert
Published: October 2023

Supplemental Figure 4. Methylation profiles using quadratic programming vs. non-negative least- squares regression using the reference matrix described in Sun et al. (3). Pearson’s correlation coefficient and p values are presented at the bottom of this figure, showing the derived contributions from each of the 12 tissue types that could be assessed.
Figure S2 from The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer
Authors: Mattox Austin K. , Douville Christopher , Wang Yuxuan , Popoli Maria , Ptak Janine , Silliman Natalie , Dobbyn Lisa , Schaefer Joy , Lu Steve , Pearlman Alexander H. , Cohen Joshua D. , Tie Jeanne , Gibbs Peter , Lahouel Kamel , Bettegowda Chetan , Hruban Ralph H. , Tomasetti Cristian , Jiang Peiyong , Chan K.C. Allen , Lo Yuk Ming Dennis , Papadopoulos Nickolas , Kinzler Kenneth W. , Vogelstein Bert
Published: October 2023

Supplemental Figure 2. The concentration of plasma cfDNA in previous described patients with cancer according to stage. (A) The concentration of cfDNA in patients of all cancer types (9). The concentration of cfDNA in patients with Stage III cancers was significantly higher than that of patients with Stage I cancers (p < 0.01). (B) The concentration of cfDNA in individual cancer types. Stage was classified according to AJCC 7th edition. The concentration of cfDNA in patients with Stage III breast cancer was significantly higher than that of patients with Stage I breast cancer (p < 0.05). For both panels, data were derived from the previously published CancerSEEK study (9).
Figure S10 from The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer
Authors: Mattox Austin K. , Douville Christopher , Wang Yuxuan , Popoli Maria , Ptak Janine , Silliman Natalie , Dobbyn Lisa , Schaefer Joy , Lu Steve , Pearlman Alexander H. , Cohen Joshua D. , Tie Jeanne , Gibbs Peter , Lahouel Kamel , Bettegowda Chetan , Hruban Ralph H. , Tomasetti Cristian , Jiang Peiyong , Chan K.C. Allen , Lo Yuk Ming Dennis , Papadopoulos Nickolas , Kinzler Kenneth W. , Vogelstein Bert
Published: October 2023

Supplemental Figure 10. In silico mixing experiments (N = 10) of buffy coat bisulfite sequencing data with liver (A), lung (B), colon epithelial cell (C), and left atrium (D) bisulfite sequencing data deconvoluted using the Moss et al. (43) reference matrix and quadratic programming shows excellent agreement between predicted and actual fractional contribution.
Table S6 from Early-Stage Breast Cancer Detection in Breast Milk
Authors: Saura Cristina , Ortiz Carolina , Matito Judit , Arenas Enrique J. , Suñol Anna , Martín Ágatha , Córdoba Octavi , Martínez-Sabadell Alex , García-Ruiz Itziar , Miranda Ignacio , Morales-Comas Clara , Carrasco Estela , Viaplana Cristina , Peg Vicente , Nuciforo Paolo , Bayó-Puxan Neus , Gonzalez-Medina Alberto , Miquel Josep M. , Gómez-Rey Marina , Villacampa Guillermo , Arévalo Silvia , Espinosa-Bravo Martín , Balmaña Judith , Dienstmann Rodrigo , Arribas Joaquin , Tabernero Josep , Vivancos Ana , Sansó Miriam
Published: October 2023

Analytical validation of the VHIO-YWBC protocol
Table S5 from Early-Stage Breast Cancer Detection in Breast Milk
Authors: Saura Cristina , Ortiz Carolina , Matito Judit , Arenas Enrique J. , Suñol Anna , Martín Ágatha , Córdoba Octavi , Martínez-Sabadell Alex , García-Ruiz Itziar , Miranda Ignacio , Morales-Comas Clara , Carrasco Estela , Viaplana Cristina , Peg Vicente , Nuciforo Paolo , Bayó-Puxan Neus , Gonzalez-Medina Alberto , Miquel Josep M. , Gómez-Rey Marina , Villacampa Guillermo , Arévalo Silvia , Espinosa-Bravo Martín , Balmaña Judith , Dienstmann Rodrigo , Arribas Joaquin , Tabernero Josep , Vivancos Ana , Sansó Miriam
Published: October 2023

VHIO-YWBC NGS panel gene list
Tables S4-S5 from Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
Authors: Guirguis Andrew A. , Ofir-Rosenfeld Yaara , Knezevic Kathy , Blackaby Wesley , Hardick David , Chan Yih-Chih , Motazedian Ali , Gillespie Andrea , Vassiliadis Dane , Lam Enid Y.N. , Tran Kevin , Andrews Byron , Harbour Michael E. , Vasiliauskaite Lina , Saunders Claire J. , Tsagkogeorga Georgia , Azevedo Aleksandra , Obacz Joanna , Pilka Ewa S. , Carkill Marie , MacPherson Laura , Wainwright Elanor N. , Liddicoat Brian , Blyth Benjamin J. , Albertella Mark R. , Rausch Oliver , Dawson Mark A.
Published: October 2023

Primer + shRNA + Taqman probe sequences
Table S2 from Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
Authors: Guirguis Andrew A. , Ofir-Rosenfeld Yaara , Knezevic Kathy , Blackaby Wesley , Hardick David , Chan Yih-Chih , Motazedian Ali , Gillespie Andrea , Vassiliadis Dane , Lam Enid Y.N. , Tran Kevin , Andrews Byron , Harbour Michael E. , Vasiliauskaite Lina , Saunders Claire J. , Tsagkogeorga Georgia , Azevedo Aleksandra , Obacz Joanna , Pilka Ewa S. , Carkill Marie , MacPherson Laura , Wainwright Elanor N. , Liddicoat Brian , Blyth Benjamin J. , Albertella Mark R. , Rausch Oliver , Dawson Mark A.
Published: October 2023

Flow antibodies
Figure S2 from Early-Stage Breast Cancer Detection in Breast Milk
Authors: Saura Cristina , Ortiz Carolina , Matito Judit , Arenas Enrique J. , Suñol Anna , Martín Ágatha , Córdoba Octavi , Martínez-Sabadell Alex , García-Ruiz Itziar , Miranda Ignacio , Morales-Comas Clara , Carrasco Estela , Viaplana Cristina , Peg Vicente , Nuciforo Paolo , Bayó-Puxan Neus , Gonzalez-Medina Alberto , Miquel Josep M. , Gómez-Rey Marina , Villacampa Guillermo , Arévalo Silvia , Espinosa-Bravo Martín , Balmaña Judith , Dienstmann Rodrigo , Arribas Joaquin , Tabernero Josep , Vivancos Ana , Sansó Miriam
Published: October 2023

Analytical validation of the VHIO-YWBC protocol for NGS
Supplementary Table S7 from An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma
Authors: Zhang Mao , Huang Yingying , Pan Jiaomeng , Sang Chen , Lin Youpei , Dong Liangqing , Shen Xia , Wu Yingcheng , Song Guohe , Ji Shuyi , Liu Fen , Wang Mengcheng , Zheng Yuyan , Zhang Sirui , Wang Zefeng , Ren Jianke , Gao Daming , Zhou Jian , Fan Jia , Wei Wu , Lin Jian , Gao Qiang
Published: October 2023

Supplementary Table S7. Patient information.
Supplementary Figures 1-12 from Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
Authors: Farin Henner F. , Mosa Mohammed H. , Ndreshkjana Benardina , Grebbin Britta M. , Ritter Birgit , Menche Constantin , Kennel Kilian B. , Ziegler Paul K. , Szabó Lili , Bollrath Julia , Rieder Dietmar , Michels Birgitta E. , Kress Alena , Bozlar Müge , Darvishi Tahmineh , Stier Sara , Kur Ivan-Maximilano , Bankov Katrin , Kesselring Rebecca , Fichtner-Feigl Stefan , Brüne Bernhard , Goetze Thorsten O. , Al-Batran Salah-Eddin , Brandts Christian H. , Bechstein Wolf O. , Wild Peter J. , Weigert Andreas , Müller Susanne , Knapp Stefan , Trajanoski Zlatko , Greten Florian R.
Published: October 2023

Supplementary Figure S1 shows light microscopic images of CRC organoids and CAFs.
Supplementary Figure S2 shows immunostaining and RNA sequencing analysis of cultured CAFs.
Supplementary Figure S3 shows chromosomal copy number changes in tumors and matched organoids.
Supplementary Figure S4 shows the transcriptional variation among tumors and organoids.
Supplementary Figure S5 shows the classification of cancer intrinsic subtypes (CRIS) in tumors, matched organoids and xenotransplants.
Supplementary Figure S6 shows the tissue microarray analysis of the of tumor samples from the colorectal cancer organoid-stroma biobank cohort.
Supplementary Figure S7 shows the association of growth characteristics with molecular features of colorectal cancer organoid-stroma biobank.
Supplementary Figure S8 shows the shows CMS and CRIS classifications of tumors and of matched organoids in different contexts.
Supplementary Figure S9 describes the establishment of a drug screening workflow in 3D organoid-stroma co-cultures.
Supplementary Figure S10 describes the development of a dual luciferase assay to study cell viability simultaneously in organoids and CAFs.
Supplementary Figure S11 demonstrates that the MET inhibitor BAY-474 sensitizes Gefitinib resistant co-cultures.
Supplementary Figure S12 shows the association of identified sensitivity and resistance signatures with gene expression and prognosis in different CMS.
Supplementary Table S4 from An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma
Authors: Zhang Mao , Huang Yingying , Pan Jiaomeng , Sang Chen , Lin Youpei , Dong Liangqing , Shen Xia , Wu Yingcheng , Song Guohe , Ji Shuyi , Liu Fen , Wang Mengcheng , Zheng Yuyan , Zhang Sirui , Wang Zefeng , Ren Jianke , Gao Daming , Zhou Jian , Fan Jia , Wei Wu , Lin Jian , Gao Qiang
Published: October 2023

Supplementary Table S4. Neutrophil-related information.
Supplementary Table S3 from An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma
Authors: Zhang Mao , Huang Yingying , Pan Jiaomeng , Sang Chen , Lin Youpei , Dong Liangqing , Shen Xia , Wu Yingcheng , Song Guohe , Ji Shuyi , Liu Fen , Wang Mengcheng , Zheng Yuyan , Zhang Sirui , Wang Zefeng , Ren Jianke , Gao Daming , Zhou Jian , Fan Jia , Wei Wu , Lin Jian , Gao Qiang
Published: October 2023

Supplementary Table S3. Signature and marker information.
Supplementary Table S2 from An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma
Authors: Zhang Mao , Huang Yingying , Pan Jiaomeng , Sang Chen , Lin Youpei , Dong Liangqing , Shen Xia , Wu Yingcheng , Song Guohe , Ji Shuyi , Liu Fen , Wang Mengcheng , Zheng Yuyan , Zhang Sirui , Wang Zefeng , Ren Jianke , Gao Daming , Zhou Jian , Fan Jia , Wei Wu , Lin Jian , Gao Qiang
Published: October 2023

Supplementary Table S2. Differential ASEs, primers and sequences information.
Supplementary Figures S1-9 from An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma
Authors: Zhang Mao , Huang Yingying , Pan Jiaomeng , Sang Chen , Lin Youpei , Dong Liangqing , Shen Xia , Wu Yingcheng , Song Guohe , Ji Shuyi , Liu Fen , Wang Mengcheng , Zheng Yuyan , Zhang Sirui , Wang Zefeng , Ren Jianke , Gao Daming , Zhou Jian , Fan Jia , Wei Wu , Lin Jian , Gao Qiang
Published: October 2023

Supplementary Figure S1. Determination of AS index in iCCA.
Supplementary Figure S2. Validation of distinct immune features in iCCA.
Supplementary Figure S3. Detection of KRAS mutation associated indicators.
Supplementary Figure S4. Exploration of the molecular mechanisms of IL1RN201/203 in iCCA.
Supplementary Figure S5. Comparison between KRAS mutant (YAK) or KRASWT (YA) iCCA mice and functional validation of IL1RN-201/203.
Supplementary Figure S6. Definition, validation and functional exploration of neutrophil clusters.
Supplementary Figure S7. Effects of T cells, especially GZMB+ CD8+ T cells, on IL1RN-201/203 efficacy.
Supplementary Figure S8. The roles of anti-PD1 Ab in KRASWT iCCA mice and anti-PD1 Ab plus anakinra in KRAS mutant iCCA mice.
Supplementary Figure S9. Immunologic features of cancer patients with or without KRAS mutation.
TABLE 4 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Top DEGs upregulated under hypoxia in EA and AA TNBC cell lines
TABLE 3 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Top genes and pathways enriched in TNBC cell lines in association with patient ancestry
Supplementary Table 4 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Supplementary table 4 displaying data output from upstream regulator analysis performed on RNA-seq data from TNBC patients in TCGA.
Supplementary Table 2 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Supplementary table 2 displaying data output from digital footprinting analysis performed on ATAC-seq data from TNBC cell lines.
Supplementary Table 1 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Supplementary table 1 displaying data output from motif enrichment analysis performed on ATAC-seq data from TNBC cell lines.
Supplementary Figure 2 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Supplemental Figure 2. Expression of genes by donor ancestry in TNBC cell lines. Top-ranked genes identified to be located in open chromatin regions with an ancestry relationship were individually confirmed to be differentially expressed at the transcript level in matched RNA-seq data from the same human TNBC cell lines. Significance testing with two-sided t-test.
FIGURE 2 from Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
Authors: Harris Alexandra R. , Panigrahi Gatikrushna , Liu Huaitian , Koparde Vishal N. , Bailey-Whyte Maeve , Dorsey Tiffany H. , Yates Clayton C. , Ambs Stefan
Published: October 2023

Patterns of differential TF binding in open chromatin regions among TNBC cell lines derived from EA and AA women. A, Overabundance of known TF motifs within differentially open regions. Heat map of top 50 most variable TFs by cell line donor ancestry based on differential ATAC signal analysis. B, Volcano plot of predicted differences in TF binding scores by patient group using digital footprinting analysis with TOBIAS. Open chromatin regions defined by TF binding sites are significantly different between cell lines from AA and EA patients. A total of 79 TFs were differentially bound in AA versus EA TNBC lines (points in red indicate TFs with differential binding score > |0.225| and FDR<0.01). A differential binding score of greater than 0.225 indicates increased binding in EA. A differential binding score of less than −0.225 indicates increased binding in AA. C, Top-ranked 10 TFs with differential binding capacities in the two donor groups identified through digital footprinting analysis.
Dysfunctional APPL1-Mediated Epigenetic Regulation in Diabetic Vascular Injury
Authors: Du Yunhui , Duan Yanru , Zhao Jianli , Liu Caihong , Zhang Zhen , Zhang John , Meng Zhijun , Wang Xiaoliang , Lau Wayne Bond , Xie Dina , Lopez Bernard L. , Christopher Theodore A. , Gao Erhe , Koch Walter J. , Liu Huirong , Liu Demin , Ma Xin-Liang , Gu Guoqiang , Wang Yajing
Published: October 2023

BACKGROUND:

APN (adiponectin) and APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) are potent vasculoprotective molecules, and their deficiency (eg, hypoadiponectinemia) contributes to diabetic vascular complications. However, the molecular mechanisms that govern their vasculoprotective genes as well as their alteration by diabetes remain unknown.

METHODS:

Diabetic medium-cultured rat aortic endothelial cells, mouse aortic endothelial cells from high-fat-diet animals, and diabetic human aortic endothelial cells were used for molecular/cellular investigations. The in vivo concept-prove demonstration was conducted using diabetic vascular injury and diabetic hindlimb ischemia models.

RESULTS:

In vivo animal experiments showed that APN replenishment caused APPL1 nuclear translocation, resulting in an interaction with HDAC (histone deacetylase) 2, which inhibited HDAC2 activity and increased H3Kac27 levels. Based on transcriptionome pathway-specific real-time polymerase chain reaction profiling and bioinformatics analysis, Angpt1 (angiopoietin 1), Ocln (occludin), and Cav1 (caveolin 1) were found to be the top 3 vasculoprotective genes suppressed by diabetes and rescued by APN in an APPL1-dependent manner. APN reverses diabetes-induced inhibition of Cav1 interaction with APPL1. APN-induced Cav1 expression was not affected by Angpt1 or Ocln deficiency, whereas APN-induced APPL1 nuclear translocation or upregulation of Angpt1/Ocln expression was abolished in the absence of Cav1 both in vivo and in vitro, suggesting Cav1 is upstream molecule of Angpt1/Ocln in response to APN administration. Chromatin immunoprecipitation–qPCR (quantitative polymerase chain reaction) demonstrated that APN caused significant enrichment of H3K27ac in Angpt1 and Ocln promoter region, an effect blocked by APPL1/Cav1 knockdown or HDAC2 overexpression. The protective effects of APN on the vascular system were attenuated by overexpression of HDAC2 and abolished by knocking out APPL1 or Cav1. The double knockdown of ANGPT1/OCLN blunted APN vascular protection both in vitro and in vivo. Furthermore, in diabetic human endothelial cells, HDAC2 activity is increased, H3 acetylation is decreased, and ANGPT1/OCLN expression is reduced, suggesting that the findings have important translational implications.

CONCLUSIONS:

Hypoadiponectinemia and dysregulation of APPL1-mediated epigenetic regulation are novel mechanisms leading to diabetes-induced suppression of vasculoprotective gene expression. Diabetes-induced pathological vascular remodeling may be prevented by interventions promoting APPL1 nuclear translocation and inhibiting HDAC2.
Expanding Pragmatism with Symbolic Interactionism: Recounting the Story of Two Frameworks
Authors: Koskinen Ilpo , Forlizzi Jodi , Battarbee Katja
Published: October 2023

This article describes the story of pragmatism and its transformation into symbolic interactionism at Carnegie Mellon University and Aalto University. In both universities, design researchers were interested in user experience in interactive systems. John Dewey's pragmatism taught them to study how experience sometimes transforms into an experience and occasionally into stories. Herbert Blumer's interactionism had its roots in Chicago School sociology, and it developed in association with pragmatism. His interactionism gave these researchers tools to study Dewey's concepts empirically. We show in the article how this theoretical connection came about after 2000 and how it has shaped research programs in these two communities since then. We also discuss the relevance of pragmatism and interactionism in our current technological landscape, dominated by social media and artificial intelligence.
The Value of Experience-Centered Design to Responsible Software Design and Engineering
Authors: McCarthy John , Wright Peter
Published: October 2023

In this conceptual article, we review experience-centered approaches to the design of personal digital interactive technologies, with a view to exploring how these approaches might be of value in understanding the experience-in-use and the responsible design of today's highly networked, data-rich, and ubiquitous software technologies. Experience-centered design research leans heavily on pragmatist philosophy for its conceptual underpinnings, particularly John Dewey's accounts of aesthetic experience and of inquiry. After reviewing this body of work, we argue that these foundations could be usefully extended to also include Dewey's approach to ethics as an empirical, situated act of moral imagination. In addition, we look to other researchers for perspectives that complement and extend Deweyan experiential pragmatics. In particular, we look to the ways in which Susan Leigh Star's account of socio-technical infrastructures and dialogical approaches to human relations together can provide important insights into the experience-in-use of today's digital infrastructure and can critically highlight issues of boundaries and privacy. We also offer pragmatic and methodological concepts that may be of value to the field of responsible software design and engineering.
Art-Kut! The Counter-Cultural and Feminist Spirituality of Shamanism in Postwar South Korean Art
Authors: Choi Sooran
Published: October 2023

On 17 January 1981, during a cold Winter Day at the height of an authoritarian military regime, a group of South Korean artists named “Baggat Misul [Outdoor Art]” gathered around a riverbank outside Seoul to interact with nature and called it “jayeon misul [nature art].” A young woman artist Yong-sin Suh performed an act the group called “a lark,” during which Suh alternated with two male artists in reading aloud sections of newspaper articles. These unhinged, free-spirited acts were inspired by the Korean folk theater tradition of pansori (traditional Korean musical opera), and kut (traditional Korean shamanistic exorcism). Korean shamanism by way of the mudang kut rituals has historically been a Korean indigenous belief intertwined with Buddhism and Taoism and stood as a counterforce to the mainstream nationalist neo-Confucian and imperial Christian conservative legacy that oppressed women and the nonconforming gender-neutral community in South Korea. The paper analyzes the Korean shamanistic elements that were utilized in performative, conceptual, and nature art practices by South Korean artists in the post-WWII period to the present, within the framework of the intersection of Korean feminism, art activism, and shamanistic spirituality.
Women in Hindu Temple Art
Authors: Sridharan Shriya
Published: October 2023

This paper will focus on the traditional or Agamic temples of South India, to explore the reasons why women are largely absent in significant hereditary roles determining the continuation of its art and ritual practices even at present. The art/ritual practice that women are primarily associated with is kolam-making. Kolams are geometric and abstract floor designs that are drawn by hand using impermanent materials like rice flour to mark the auspiciousness of an entryway, a festive occasion or time of the day. These are mostly done as voluntary services at temples by women in the locality, especially during festival days. The nature of this art is informal and ephemeral compared to the other codified and more permanent temple art forms, which women are not allowed to make. The limited and conditional access for female practitioners in Hindu temples is based upon restrictions constructed around the divine power, which the temple is designed to establish and maintain. This paper will study and locate the absence of women as contemporary temple art practitioners in the intersection of the meanings of being female and the meanings of Hindu temple forms and spaces.
Main Contents of the Law of the Democratic People’s Republic of Korea on the Red Cross Society and Commentary
Authors: Ro Kum-Chol , Son Hye-Ryon
Published: October 2023

On 29 July 2021, the Presidium of the Supreme People’s Assembly of the Democratic People’s Republic of Korea (DPR Korea) amended and supplemented the Law of the DPR Korea on the Red Cross Society. The Law is a branch law of the DPR Korea that uniquely provides such things as the organization, function, and principles of conduct of the Red Cross Society and use of the Red Cross mark. The amendment and supplementation of the Law further consolidated the legal guarantee for the smooth operation of humanitarian activities of the Red Cross Society in the DPR Korea. This paper provides a summary of the main contents of the Law and comments on the basis of the Fundamental Principles of the International Red Cross and Red Crescent Movement and the requirements of international humanitarian law, including the recommendations of the International Federation of Red Cross and Red Crescent Societies on the activities of the Red Cross Society and the use of the Red Cross emblem.
Legalising Same-Sex Marriage in Taiwan
Authors: Hsu Yu-Fang , Su Tzu-Chiao
Published: October 2023

This article examines the case of Taiwan’s anti-same-sex marriage referendum of 2018. This case shows that a referendum can severely affect the model of constitutional sovereignty which has guided Taiwan since its democratisation. The fact that populists were able to use the referendum as a tool to delegitimise the state organs, we argue, throws light on the relationship between populism and direct democracy.
Semantic Externalism and the History of Ideas: A Critical Review
Authors: Handby Edmund
Published: October 2023

A recent innovation in the study of methods in the history of ideas is the introduction of elements of semantic externalism from the philosophy of language. Studies that rely on semantic externalism have done so to address particular questions of method in political theorising, including the interpretation of ‘essentially contested concepts’, and the issue of relativism in historical contextualism. In this paper, I critically review the use of semantic externalism, and associated methods such as Kripke’s causal theory of reference, in the history of ideas. I explore the barriers that might prevent the use of externalism, and how studies relying on externalism seek to overcome such barriers. I then assess both the implications of relying on externalism, as well as a set of limitations.
Featuring Fiqh: the Representation of Islamic Law in Egyptian Historical Dramas
Authors: Skovgaard-Petersen Jakob
Published: October 2023

Although they may have learned the norms and practices of fiqh at home and in school, most Muslims have scant knowledge of the ways in which their religious laws and mores were practiced in pre-modern times. Indeed, when it comes to imagining and understanding the role of fiqh in earlier Muslim societies, many contemporary Muslims get their information through fictional treatments, particularly from films and television dramas. For Arab Muslims, the relevant medium here is the musalsal, the 30-episode Ramadan drama.

This article is a preliminary investigation into the role of fiqh in Egyptian historical films and musalsalāt. Based on collected scenes of fiqh – judges passing sentences, muftis issuing fatwas, teachers instructing, and student discussions – it identifies the issues at stake and analyzes the style of argumentation, the exercise of authority, and the general image of a fiqh-based society created in films and dramas. While the fuqahāʾ only play a minor role in Egyptian film, they are prominent in Arabic historical and religious musalsalāt, often, but not exclusively, produced in Egypt. In these two genres, we have biopics of major religio-legal figures, such as the founders of the four legal schools, major theologians, 19th century reformers, and a few modern ʿulamaʾ.

Tracing the evolving treatment of fiqh and fuqahāʾ from the early dramas of the 1980s up to today, this article focuses on the themes of judicial independence, justice for the poor, corruption, and the intellectual process behind rulings. It argues that, overall, the lesson of the musalsalāt is a positive one: Shariʿa works, authoritarian rule has the capacity to be enlightened, and the key to effective leadership is appointing the right people to govern, or judge. The article concludes by discussing these messages in a contemporary Egyptian setting.
Transoceanic Print Histories: Twentieth-Century Swahili Muslim Networks in the Indian Ocean
Authors: Raia Annachiara
Published: October 2023

At a time of sociocultural changes that started questioning established Islamic learning traditions (independence years, post-Cold War/book market liberalization), printing diasporas exerted influence on the circulation of Islamic texts in East Africa: published overseas (Cairo, Beirut, and the Indian subcontinent) and/or locally reprinted on the Swahili-speaking Islamic coast, they came to play a seminal role in negotiating Swahili Muslim literary culture. How have transoceanic religious and intellectual networks operating beyond national borders become intertwined? In this paper, the beginnings of Swahili Muslim book publishing—and the entities underpinning it, such as Nairobi’s Islamic Foundation Center, a Pakistani-oriented charitable foundation—will be outlined. I will then delve into the history of Indian-and-Swahili family-run publishers Adam Traders based in Mombasa in order to tackle hitherto neglected transoceanic connections and patterns of influence across the sea.
Proximity and distance – Review of seaweed communities and the marine environment along the coasts of the Levant Basin
Authors: Einav Rachel
Published: October 2023

This paper presents an analysis of the environmental factors affecting the ecology of seaweed (macroalgae) populations in the Levant Basin, attempting to identify both similar and different factors that determine distribution. Using correspondence analysis (CA) the study found a significantly similar pattern in the relations between countries and macroalgae – both for the whole group and within each phylum: Chlorophyta, Ochrophyta, Rhodophyta. The study identified two different macroalgae populations in the Levant Basin: The easternmost group living in open water off the coasts of Syria, Lebanon and Israel, and the shell group found in more sheltered waters in Egypt, Turkey, the Turkish Republic of Northern Cyprus, and Republic of Cyprus (Greece Cyprus): south Cyprus; and the North Cyprus. The differences between the two communities can be explained by dynamic wave activity. Following a taxonomic and nomenclatural revision according to AlgaeBase, of 693 species to date recorded from the studied area, only 573 species remained. 26 of them appear in all 7 countries and other 68 in 6 countries. 204 species appear in only one country. 3 or 4 species have only been described in the Middle East and could be endemic.
Female-dependent factors affect sex allocation in Lesser Kestrels Falco naumanni
Authors: Papakosta Malamati A. , Bakaloudis Dimitrios E. , Goutner Vassilis , Yosef Reuven , Kotsonas Evangelos , Iezekiel Savvas , Vlachos Christos G.
Published: October 2023

The sex ratio of nestlings is a crucial population determinant in rare and/or endangered species. We investigated the role of female body condition and female-related traits in Lesser Kestrel (Falco naumanni) nestling sex allocation at a nest-box colony in central Greece. We used the total clutch volume and size, female weight, hatching dates, body length, wing length, tail length, tarsometatarsus, and bill length as explanatory variables of the number of male nestlings (the response variable) using CART model analysis. This analysis showed that the reproduction output was biased towards male nestlings when female parents were shorter in body length and clutch size and volume were smaller. The skewed sex ratio favoring females, 1:2.35, suggests that when female parents are in good condition, they invest most in good-quality female nestlings, providing a reproductive advantage and increased long-term fitness.
Contribution to the knowledge of Chinese Gryllacrididae (Orthoptera) XXI: New reports from Fujian Province
Authors: ZHANG QIANWEN , PANG SIYU , BIAN XUN
Published: October 2023

In this study, we describe and illustrate two new species and the female of Metriogryllacris (Metriogryllacris) obscurata Zhang, Pang & Bian, 2022 based on the specimens from Fujian Province. The new erected Homogryllacris foveolis sp. nov. (Chinese name: 凹板同蟋螽) is very similar to Homogryllacris rufovaria Liu, 2007 in appearance, but the two can distinguished by the spines of male tenth abdominal tergite and shapes of male subgenital plate. All the specimens are deposited in Guangxi Normal University.
Enhanced Dissipation of Internal Tides in a Mesoscale Baroclinic Eddy
Authors: Wang Yang , Legg Sonya
Published: October 2023

The dissipation of low-mode internal tides as they propagate through mesoscale baroclinic eddies is examined using a series of numerical simulations, complemented by three-dimensional ray tracing calculations. The incident mode-1 internal tide is refracted into convergent energy beams, resulting in a zone of reduced energy flux in the lee of the eddy. The dissipation of internal tides is significantly enhanced in the upper water column within strongly baroclinic (anticyclonic) eddies, exhibiting a spatially asymmetric pattern, due to trapped high-mode internal tides. Where the eddy velocity opposes the internal tide propagation velocity, high-mode waves can be trapped within the eddy, whereas high modes can freely propagate away from regions where eddy and internal wave velocities are in the same direction. The trapped high modes with large vertical shear are then dissipated, with the asymmetric distribution of trapping leading to the asymmetric distribution of dissipation. Three-dimensional ray tracing solutions further illustrate the importance of the baroclinic current for wave trapping. Similar enhancement of dissipation is also found for a baroclinic cyclonic eddy. However, a barotropic eddy is incapable of facilitating robust high modes and thus cannot generate significant dissipation of internal tides, despite its strong velocities. Both energy transfer from low to high modes in the baroclinic eddy structure and trapping of those high modes by the eddy velocity field are therefore necessary to produce internal wave dissipation, a conclusion confirmed by examining the sensitivity of the internal tide dissipation to eddy radius, vorticity, and vertical scale.

Significance Statement

The oceanic tides drive underwater waves at the tidal frequency known as internal tides. When these waves break, or dissipate, they can lead to mixing of oceanic heat and salt which impacts the ocean circulation and climate. Accurate climate predictions require computer models that correctly represent the distribution of this mixing. Here we explore how an oceanic eddy, a swirling vortex of order 100–400 km across, can locally enhance the dissipation of oceanic internal tides. We find that strong ocean eddies can be hotspots for internal tide dissipation, for both clockwise and anticlockwise rotating vortices, and surface-enhanced eddies are most effective at internal tide dissipation. These results can improve climate model representations of tidally driven mixing, leading to more credible future predictions.
Tears Behind the Closed Doors: A Logistic Analysis of Domestic Violence Against Women in West Bengal, India
Authors: Biswas Priyanka , Das Chatterjee Nilanjana
Published: October 2023

In this present study, the focus has been given to excavating the generalities of domestic abuse against women in the Indian state of West Bengal and understanding the possible determinants. The study findings revealed that 69.68% of study respondents throughout Bengal often experienced any form of domestic violence in their lifetime. Mostly the traditional patriarchal structure that governs Bengal’s society endorses vulnerability among the ever-married women in the family environment, yet some other determinants viz. socio-demographic, socio-cultural as well as situational factors are significantly associated with the victimization of domestic abuse among women in Bengal’s society. This study aims to contribute to society and might help policymakers to address this societal issue more efficiently.
Personal Reflections on the Life and Legacy of Bill Spriggs
Authors: Mishel Larry , Wilson Valerie
Published: October 2023

Dr. William E. Spriggs, chief economist of the AFL-CIO and economics professor at Howard University passed away unexpectedly in June 2023. In honor of his memory, the authors discuss his many professional accomplishments and share personal reflections on the economist, mentor, colleague and friend they and others knew simply as Bill.
Digital-twin-controlled ventilation for real-time resilience against transmission of airborne infectious disease in an indoor food court
Authors: Tan Jonathan Koon Ngee , Law Adrian Wing-Keung , Kumar Maan Akshay , Cheung Sai Hung
Published: October 2023

During a disruption, actionable insights generated from real-time data of the disrupted system can be used to dynamically recalibrate mitigation and recovery responses but there is currently a paucity of investigation on such assessment and management of resilience in real time. In this study, we propose the concept of real-time resilience to encapsulate the capacity of a disrupted system to continuously recalibrate its responses and minimize its damage. Quantitative metrics to assess the real-time resilience are also established. Subsequently, a digital-twin-based control for mechanical ventilation systems was developed as a tool to enable real-time resilience against airborne infection in indoor spaces. For demonstration, numerical simulations were performed with the adoption of the new tool in an indoor food court. Results showed that the gross resilience of the diners was enhanced in terms of improvements to the metrics of disruption duration (26%–61%), loss of resilience (2%–39%), and average rate of recovery (26%–74%). At the same time, the tempo-spatial variations suggested that increasing the ventilation rate increased the dilution and dispersion of infectious aerosols simultaneously, which can have opposing effects on individual resilience depending on the diner’s location. The trade-off between real-time resilience and energy use was discussed based on the results. Practical applications: This study proposed a new tool based on the concept of real-time resilience to control ventilation to mitigate the indoor transmission of airborne infectious disease. The tool utilized numerical simulations to assess the tempo-spatial variation of infection risks and determine the adaptive changes needed for risk mitigation based on the predictive assessment. The evaluation of the tool using the proposed metrics of real-time resilience was demonstrated and the results showed that adoption of the tool can lead to improvements in disruption duration, loss of resilience, and average rate of recovery for diners in a food court.
Viral cash: Basic income trials, policy mutation, and post-austerity politics in U.S. cities
Authors: Doussard Marc
Published: October 2023

During the covid-19 pandemic, basic income pilot programs spread across U.S. cities like the novel coronavirus itself. The policy of no-strings-attached cash transfers marks a potentially significant change in the development of post-austerity politics, but only if basic income programs can endure beyond their trial phase. This paper centers the phenomenon of viral cash—cash transfer programs that mutate and multiply like the coronavirus to which they respond—as a means of assessing the possible pathways from trial programs to standing policy. Drawing on case studies of pilot programs in Minneapolis, St. Paul, and Denver, I argue that basic income pilots extend beyond their end-date by creating individual and institutional constituencies invested in unconditional cash transfers. Focusing on these constituencies draws attention to basic income’s role in popularizing child tax credits, program cash stipends and other policy reforms recently enacted by cities and states. Seen this way, basic income’s virus-like susceptibility to mutation plays a key role in seeding support for urban policies and politics that counter prior austerity by centering investment in human capacity.
Effect of a curved turning vane on the heat transfer and fluid flow of four-pass internal cooling channels of gas turbine blades
Authors: Pouyaei Pouya , Kayhani Mohammad Hassan , Norouzi Mahmood , Bakhshinejad Bahambari Alireza , Kim Mirae , Kim Kyung Chun
Published: October 2023

This numerical study examined the effects of a curved turning vane on the heat transfer and pressure loss of a four-pass internal cooling channel. Three-dimensional omega-based Reynolds stress (RSM-ω) turbulence model equations were used in the computation process. Three different curved turning vane configurations were studied using a simple, without a turning vane under stationary and rotating conditions for Reynolds numbers between 20,000 and 60,000 and a rotation number of 0.042. The numerical results showed good agreement with previous experimental data. Under both stationary and rotating conditions, the curved turning vane in a hub turn reduced the pressure drop significantly compared to the conventional turning vanes. Although a curved turning vane attenuated overall heat transfer, the local heat transfer increased it in particular regions, such as the hub turn and the fourth turn of cooling passages, particularly in cases with smaller radii. Coolant flow through the hub turn of the serpentine channel can reduce recirculation, separation, and flow impingement, which are unfavorable factors of pressure loss, owing to the semi-circular configuration of the curved turning vane. Regarding the rotating conditions, four-pass channels with a smaller radius of a curved turning vane provide better overall cooling performance.
‘Please don’t insult Dog. He is a loyal friend!’ The use of animal metaphors for evaluation and positioning on a Chinese Political Web Forum
Authors: Li Long , Dreyfus Shoshana
Published: October 2023

This study focuses on how animal metaphors are deployed by Chinese social media users to evaluate others and negotiate social positioning in online grassroots political discourse. Animal metaphors are important devices for expressing judgement of human behaviour. This is due, first, to perceived similarities and differences between humans and (other) animals and, second, due to the ‘Great Chain’ idea of human superiority and dominance over animals. Animal metaphors are commonly deployed in communication that is interpersonally volatile, such as on social media, regardless of what language this occurs in. Through an analysis of the interpersonal systems of appraisal and involvement, we found that contributors often adopt highly charged animal metaphors to negatively evaluate each other and to create and maintain a left-right political division.
D-Dimers Variability in the Perioperative Period of Breast Cancer Surgery Helps to Predict Cancer Relapse: A Single-Centre Prospective Study
Authors: Dybowska Małgorzata , Dybowski Dariusz , Szturmowicz Monika , Jóźwik Adam , Lewandowska Katarzyna , Sobiecka Małgorzata , Tomkowski Witold
Published: October 2023

Background

The importance of D-dimers (DD) assessment in the diagnostic algorithm of venous thromboembolic (VTE) disease is well known. Increase of DD concentration may be also associated with neoplastic disease. Many studies documented that high concentration of DD before solid tumour surgery indicates more advanced disease and poor life expectancy. The prognostic value of the DD concentration variability in the perioperative period, in women undergoing breast cancer surgery, has not been analysed so far. Thus, the aim of the present prospective study was to assess whether the trend of DD concentration changes in the perioperative period may predict cancer recurrence in women undergoing breast cancer surgery.

Materials and methods

189 consecutive women with histopathological diagnosis of breast cancer (BC) referred for surgical treatment were included. DD concentration was measured twice in each patient: at the time of admission to hospital and at the time of discharge home. Enoxaparin in standard dose of 40 mg daily s. c. was used as primary VTE prophylaxis in all of the patients.

Results

The recurrence of BC, within 1 year observation time, occurred in 13 patients (6.8%), in 11 (5.8%) patients with DD increase after surgery and only in 2 (1.1%) without an increase in DD, P = .0179. Increase in DD concentration after BC surgery was an independent positive predictor of disease relapse (OR 8.600, LCI 1.451, UCI 96.80, P = .0371) together with the lack of postoperative radiotherapy (OR 6.009, LCI 1.305, UCI 31.95, P = .0245), whereas the lack of postoperative chemotherapy predicted no BC relapse (OR .07355, LCI .0056, UCI .58, P = .0245).

Conclusions

Increase of DD in the early postoperative period may be considered as additional independent predictor of recurrence of BC within 1 year.