bluuebunny/crossref_metadata_2025 huggingface dataset:
Long Low-profile Proximal Tibial Locking Plate for the Fixation of Periprosthetic Femoral Fractures Above the Prosthesis: A Pilot Study
Authors:   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran., Jabalameli Mahmoud , Karimi Amirali ,   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran., Jokar Rahmatalah ,   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran., Mohammadpour Mehdi ,   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran., Yahyazadeh Hooman ,   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran., Talebi Sina ,   Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Published: January 2022

Background: Anatomic distal femoral plates locking compression plate (LCP) are generally used for the fixation of distal femoral fractures. However, they are not suitable for periprosthetic femoral fracture after total knee arthroplasty (TKA), mainly owing to the impingement with prosthesis. Objectives: In this case series, we report the outcome of proximal tibial LCP fixation in the treatment of periprosthetic femoral fracture after TKA. Patients and Methods: Twelve patients with a periprosthetic femoral fracture who underwent surgical treatment were included. According to Su et al. classification, all fractures were type II, originating from the femoral component with proximal extending. Fractures were managed with open reduction and plate fixation. The plate choice was either a long low-profile proximal tibial LCP (n=9) or a short anatomic distal femoral LCP (n=3). Results: The study population included one male and 11 females with a mean age of 74.5±9.3 years and a mean follow-up of 2.8±1.3 years. Union of fracture was observed in all fractures that were fixed with a long locking plate during a mean period of 3.1±2.1 months. Fixation failed in all three patients who were managed with a short plate. These patients underwent revision surgery with a long low-profile proximal tibial LCP. In one of them, the fixation failed again and finally fixed with tumor prosthesis. The other two fractures were united with no complications. Conclusion: Long low-profile proximal tibial LCP omits the problem of impingement by prosthesis, which is caused by short anatomic distal femoral LCP in the treatment of periprosthetic femoral fractures above the prosthesis. However, future large-scale comparative studies are required before we can recommend it for routine implications in these fractures.
Assessment Methods of Knee Joint Arthrokinematics: A Review of Literature
Authors:   Department of Corrective Exercise and Sport Injuries, Faculty of Physical Education and Sports Sciences, University of Guilan, Guilan, Iran., Norasteh Ali Asghar , Zarei Hamed ,   Department of Corrective Exercise and Sport Injuries, Faculty of Physical Education and Sports Sciences, University of Guilan, Guilan, Iran.
Published: January 2022

Context: The present study provides an analysis of methods in assessment and measurement of knee arthrokinematic movements. Evidence Acquisition: in this study, an exhaustive review of the methods for assessment of knee joint arthrokinematics is provided. For this, some known databases including Science Direct, PubMed, EMBASE, CINAHL, and Google Scholar, for the period 1985 to February 2020 are explored. Results: After the assessment steps, 14 articles were chosen based on the criteria and objectives of the research; 13 articles in entirety and one as a summary. Through a review of the studies, it was observed that various methods were used in assessment and measurement of the knee joint arthrokinematic movements. In the beginning, focus was on transitional motion in which knee arthrokinematic movements were studied in static state; but with time, knee transitional movement was studied in dynamic state as well. More recent studies scrutinized three main types of arthrokinematics: motion rolling, gliding and spinning. There were also studies that tried to implement tools which required minimum cost and scrutinized the knee arthrokinematic movements without complicated state-of-the-art equipment. All the said equipment were designed with the aim of diagnosis of how the arthrokinematic movements of an injured knee compared to a healthy one. Conclusion: Results of our analysis show that the literature is rich with a variety of instruments for measuring knee arthrokinematic movements. By classifying the instruments, it was found that studies of four different measurement methods including static, dynamic, functional and qualitative have examined the arthrokinematic movements of the knee.
A gestão do conhecimento nas organizações
Authors: Muririua Eduardo dos Santos Arlindo
Published: January 2022

A Gestão do Conhecimento permite o registro de todo o conhecimento gerado em uma organização. O objetivo desse armazenamento de dados e informações é o seu uso no futuro, seja ele distante ou próximo. Portanto, a Gestão do Conhecimento é uma forma de valorizar e enriquecer a qualidade dos dados, que são elementos tangíveis e, no geral, abundantes dentro das organizações. Diante desse contexto, este artigo tem como questão-norteadora: Qual a importância da gestão do conhecimento nas organizações? Portanto, o trabalho tem por objetivo demonstrar a importância da gestão do conhecimento nas organizações. Quanto à metodologia, optou-se por uma abordagem exploratória e, para a coleta de dados, foi realizada uma pesquisa bibliográfica. A partir dela, propõe-se uma revisão de literatura. Com base na pesquisa, chegou-se ao seguinte resultado: o gerenciamento do conhecimento organizacional é um elemento importante nas organizações pois a aprender, a criar e a converter esse conhecimento em ações práticas e eficientes, o que implica preparar o ambiente organizacional como um todo para que isto seja viável.
Il tabulario dei Monasteri di Santa Maria di Licodia e di San Nicolò l'Arena di Catania
Authors: Angela Carbonaro Rita
Published: January 2022

Il saggio si articola in due parti. Da una parte si presentano i contributi di vari autori, ciascuno secondo la propria specializzazione, riguardanti gli oltre cento pezzi del tabulario dei Monasteri di Santa Maria di Licodia e di San Nicolò l'Arena della diocesi di Catania. Per la prima volta in questa sede inventariati: i singoli pezzi recano sulla coperta la segnatura archivistica (numero ordinale: 1, 2, 3, eccetera), la data cronica, la data topica e relativa segnatura della riproduzione digitale come emerge dalla Tabella n.1 (Biondi/Proietto). La schedatura generale, a cura di Biondi / Mirabella dei documenti tratti dai singoli pezzi inventariati, in rigoroso ordine cronologico, secondo i moderni criteri di misura del tempo assai diversificati dal periodo di riferimento, reca, oltre la data cronica, l'indizione e la data topica, il regesto dell'atto notarile come da tabella n. 2 (Biondi/Proietto). Nella seconda parte si tratteggia la storia del Fondo Benedettino in cui si contengono sin dalla sua costituzione oltre a queste qui proposte anche novecento e diciannove documenti regestati da Carmelo Ardizzone già nel 1927 e altri ancora da inventariare.
Il peer mentoring per favorire lo sviluppo professionale della docenza universitaria: l'esperienza dell'Università di
Authors: Piazza Roberta , Rizzari Simona
Published: January 2022

Il contributo descrive l'esperienza di ricerca e formazione di peer mentoring condotta dall'Ateneo di Catania per il miglioramento delle competenze didattiche dei docenti "esperti" (senior) dell'Ateneo. L'azione ha riguardato la formazione di figure esperte chiamate a supportare i colleghi nella costruzione di esperienze di sviluppo personale e di innovazione didattica. Vengono descritte le scelte teorico-metodologiche che hanno fatto da sfondo al percorso di ricerca-azione progettato e al modello formativo adottato. Sono analizzate le varie fasi che hanno visto la realizzazione dell'esperienza in Ateneo, che ha coinvolto numerosi docenti appartenenti a diverse aree disciplinari.
Sicurezza sul lavoro e cooperazione del lavoratore
Authors: Pascucci Paolo
Published: January 2022

Il saggio analizza il particolare ruolo del lavoratore in tema di sicurezza sul lavoro, destinatario della disciplina di tutela ma anche soggetto obbligato a cooperare con il datore di lavoro per rendere efficiente il sistema di prevenzione aziendale. Dopo aver evidenziato il carattere dove-roso e non solo oneroso della cooperazione creditoria del lavoratore e le ricadute di tale posi-zione sul piano del contratto di lavoro e dell'esercizio dei poteri datoriali, l'autore esamina le previsioni del d.lgs. 81/2008 sugli obblighi di sicurezza del lavoratore per poi passare a rico-struire i principali orientamenti della giurisprudenza in merito alle responsabilità di un infortu-nio di cui il lavoratore sia stato artefice o coartefice, soffermandosi in particolare sulla questione della configurabilità del concorso di colpa del lavoratore. Infine, soffermando l'attenzione su due recenti sentenze della Corte di Cassazione che limitano le ipotesi del con-corso colposo del lavoratore a causa della prevalenza delle violazioni del datore di lavoro, propone di rileggere la questione alla luce delle norme del d.lgs. 81/2008 che responsabilizzano il lavoratore come parte attiva del sistema di prevenzione.
"La rimozione e il ritorno degli oggetti cattivi (con particolare riferimento alle ‘nevrosi di guerra')" (1943)
Authors: Ronald Dodds Fairbairn William
Published: January 2022

In questo lavoro del 1943, Fairbairn espone la sua concezione di una teoria della personali-tà, basata sulle relazioni oggettuali, da cui deriva l'innovativa visione di una psicopatologia incentrata sullo studio delle relazioni dell'Io con i suoi oggetti interiorizzati. Partendo dall'osservazione di bambini vittime di attacchi sessuali ed aggressivi, Fairbairn descrive co-me, attraverso processi di incorporazione, interiorizzazione e identificazione, il bambino assu-me su di sé il peso della malvagità subita, tentando così di reinstaurare un senso di sicurezza esterna con la conseguente patologica presenza di oggetti cattivi interiorizzati. L'autore ci mo-stra come la necessità di far fronte a tale insicurezza interna comporterà da parte del bambino l'utilizzo di costose difese per fronteggiare il senso di persecutorietà che ne deriva. Fairbairn ritrova conferma delle sue asserzioni attraverso la rilettura del saggio freudiano Una nevrosi demoniaca nel secolo decimosettimo (1922). Rilegge quindi fenomeni, quali la reazione tera-peutica negativa, la coazione a ripetere ed il trauma medesimo, alla luce delle sue innovative considerazioni teoriche, servendosi delle osservazioni cliniche e psicoterapeutiche tratte dalla sua esperienza di ufficiale medico con pazienti affetti da disturbi psichici post traumatici, nel corso del secondo conflitto mondiale.
Perché Orfeo si è voltato indietro?
Authors: Parsons Michael
Published: January 2022

L'autore ricorre al mito di Orfeo ed Euridice per riflettere sulla necessità della coesistenza nella vita pschica di temporalità e atemporalità, percezione concreta e appercezione creativa, nel senso di Winnicott e di Enid Balint. Orfeo deve voltarsi a cercare Euridice per controllare con lo sguardo che lei sia lì davvero concretamente perché non riesce a sognarla. Euridice rappre-senta dunque la potenziale vitalità di Orfeo, dove si coniugano realtà e immaginazione; mentre il ritorno di Euridice agli inferi simboleggia la perdita della vitalità immaginativa e creativa. Co-sì, in termini bioniani, gli analisti hanno bisogno di sognare i loro pazienti per aiutare i pazienti a sognare se stessi.
Il caso clinico di Giulia. Il lockdown da COVID-19 come evento scatenante di episodi di alimentazione incontrollata
Authors: Russo Benedetta , Pizzi Elisabetta
Published: January 2022

Le autrici presentano il caso clinico di una paziente di 19 anni con un funzionamento perfezionistico, apparentemente asintomatica prima del primo lockdown dovuto alla pandemia da COVID-19. L'isolamento sociale e l'interruzione delle attività quotidiane caratteristici del lockdown inducono nella paziente sintomi depressivi e ansiosi che esitano in un incremento dell'alimentazione e del peso corporeo, percepiti come disturbanti dalla paziente. L'isolamento sembra costituire il primo evento scatenante (trigger) di stati mentali problematici gestiti con una strategia disfunzionale (l'alimentazione incontrollata), le cui conseguenze (l'incremento del peso corporeo) slatentizzano il sottostante senso di inadeguatezza e di vulnerabilità personale della paziente. Terapeuta e paziente intraprendono una psicoterapia cognitivo-comportamentale ad indirizzo metacognitivo-interpersonale, integrata con altri modelli terapeutici specifici per la regolazione emotiva (terapia dialettico-comportamentale) e la cura dei traumi (EMDR e terapia sensomotoria).
Sono come tu mi vuoi. La storia di G. Alla ricerca del suo posto nel mondo
Authors: Gorga Maria
Published: January 2022

Partendo dal caso clinico della giovane G., l'Autrice propone una lettura della storia raccontata secondo il modello sistemico relazionale. Verranno messi in luce gli aspetti relativi alla fase del ciclo di vita della protagonista del racconto con l'epoca storica in cui si svolgono le vicende, commentando con una proposta terapeutica ad impostazione sistemica. Viene proposta in prima battuta una presa in carico terapeutica di tipo individuale volta a sostenere la ragazza nel naturale processo di individuazione per passare ad una seconda fase del lavoro in cui è prediletto un intervento terapeutico con allargamento delle convocazioni all'intero sistema familiare di riferimento e lavorare secondo il modello di Canevaro con il rituale dello zaino.
L'adolescente e la pandemia da COVID-19. Intervista al prof. Ugo Sabatello
Authors: Sabatello Ugo , Rogora Chiara
Published: January 2022

È ormai chiaro all'opinione pubblica e soprattutto a noi sanitari che operiamo nel l'ambito della salute mentale in età evolutiva, che la pandemia da COVID-19, ma soprattutto le restrizioni sociali che ne sono derivate, sono state un detonatore per il deflagrare della sofferenza psichica, per una larga parte della popolazione giovanile. Gli adolescenti in particolare sembrano essere coloro che stanno pagando il prezzo più alto. Sembra esserci stata un'impennata di diagnosi importanti come gravi disturbi dell'umore, cutting, tentativi di suicidio, disturbi del comportamento alimentare ecc. L'intervista che segue vuole fare il punto sulla situazione dei Servizi ospedalieri di Neuropsichiatria Infantile che insieme ai Servizi territoriali sono stati "presi d'assalto". Le richieste di aiuto, di ricovero, di presa in carico sono nettamente aumentate e sproporzionate rispetto alla disponibilità di posti letto e/o disponibilità di valenze per la presa in carico. L'intervista è stata concessa dal dott. Ugo Sabatello che ha accettato di rispondere per iscritto alle domande curando così personalmente la bibliografia e la forma espositiva.
Nudes. La vulnerabilità dell'adolescente tra rivoluzione digitale e trasformazione antropologica
Authors: Pelli Massimo
Published: January 2022

L'articolo propone una riflessione a partire dalla visione della serie televisiva "Nudes" su quella che sembra essere una trasformazione antropologica del modo con cui l'adolescente affronta questa fase della vita che si situa tra la fine dell'infanzia e il giovane adulto in fase di organizzazione. Per definizione un'età di passaggio in cui l'adolescente deve confrontarsi con rapidi mutamenti dell'immagine di sé, sia dal punto di vista corporeo che psicologico e relazionale. Scuola e famiglia sono lontani e assenti. L'uso dei dispositivi digitali, il revenge porn e la diffusione non consensuale di immagini intime online sono un epifenomeno di questa trasformazione antropologica dell'adolescente sospeso tra bisogno di appartenenza e bisogno di individuazione. L'articolo include un'intervista a Laura Luchetti, regista della serie televisiva "Nudes", che attraverso tre storie diverse di adolescenti ci parla del fenomeno del revenge porn e della diffusione non consensuale di immagini intime che sta diventando un fenomeno sempre più attuale.
Gli strumenti del colloquio: considerazioni cliniche
Authors: Tere Powell Ingrid
Published: January 2022

Il seguente articolo introduce la metodologia utilizzata nel lavoro di supporto psicologico ai migranti richiedenti asilo e ai titolari di protezione - che seguo come psicologa del Centro Astalli Trento. Nel testo verranno presentati gli strumenti impiegati durante la pratica clinica - molti dei quali venivano portati a colloquio dall'utenza - come ad esempio: le cartine geografiche, i manufatti, le foto, i video ecc. Questi strumenti mi hanno permesso di lavorare in chiave etno-clinica e sono stati negoziati durante la relazione di sostegno ai beneficiari del servizio.
Utilizzare la TADS-Interview di S. Boon e H. Matthess per la diagnosi dei Disturbi Dissociativi e Complex PTSD
Authors: Cavalletti Matteo , Boldrini Maria Paola , Catania Alessandra , Fusco Valeria , Serra Nicoletta , Tagliavini Giovanni
Published: January 2022

La Trauma and Dissociation Symptoms Interview di S. Boon e H. Matthess (da qui TADS-I) è un'intervista clinica semi-strutturata, composta da 214 domande, che ha lo scopo di valutare in modo approfondito i sintomi dissociativi e i sintomi correlati al trauma. L'obiettivo principale della TADS-I è valutare la gravità e la qualità dei sintomi dissociativi e di tutti gli altri sintomi clinici che si possono sviluppare a seguito di una o più esperienze traumatiche. Con l'attuale versione della TADS-I è possibile superare il limite di altri strumenti dedicati alla diagnosi dei sintomi dissociativi, in quanto sono presenti più indicatori specifici per differenziare questi due aspetti. L'obiettivo, a cui questo lavoro dà un primo contributo, è lo studio e lo sviluppo di nuovi profili diagnostici che permetteranno di osservare in uno stesso grafico, per ogni scheda sintomatologica, frequenza, distress, gravità sintomatologica, gravità sintomatologica con alterazione di coscienza e gravità sintomatologica con possibile divisione del sè attualmente in corso.
Verso la media literacy: pratiche e prospettive
Authors: Farinacci Elisa , Manzoli Giacomo
Published: January 2022

The increasingly pervasive mediatization of our daily lives has led to pervasive media consumption and increased production and sharing of data and information. With the outbreak of the Covid-19 pandemic, media education has been transformed into an all-encompassing category that was asked to fulfill the needs and expectations pertaining to other disciplines. This progressive extension of the area of expertise of media education requires to rethink its research focus, its intervention practices in educational environments, and its regulation at the State level in order to guarantee its full legitimacy and recognition both inside and outside the schooling system.
Il Patto per il lavoro della regione Emilia-Romagna: una lettura di relazioni industriali
Authors: Seghezzi Francesco
Published: January 2022

L'autore analizza il Patto per il lavoro firmato in Emilia Romagna nel luglio del 2015 e rinnovato nel dicembre del 2020 nella prospettiva delle relazioni industriali. In particolare si concentra sui contenuti del patto e sulle ragioni che hanno spinto le parti sociali a sottoscriverlo. L'autore mostra le differenze con il ricco panorama di patti degli anni Novanta, nei quali i contenuti erano più focalizzati su singole azioni connesse alle politiche del lavoro. Nel Patto per il lavoro l'autore individua un più ampio approccio delle parti sociali alle tematiche del lavoro con un interesse per le politiche industriali, le politiche del mercato del lavoro e le politiche della formazione. Emerge che le parti sociali agiscano per legittimare la loro azione specifica a livello aziendale o territoriale attraverso una partecipazione attiva nella definizione del più ampio scenario delle politiche territoriali insieme all'attore pubblico.
Organizzare i servizi nei processi di welfare territoriale. L'esperienza dell'Emilia-Romagna nell'offerta di servizi ai cittadini migranti
Authors: Costantini Eleonora , Bonacini Luca
Published: January 2022

La scommessa di questo lavoro è di indagare come il sistema locale dei servizi sociali abbia reagito all'impatto dei flussi migratori, in un contesto regionale come l'Emilia-Romagna, descrivendo le principali dimensioni intorno alle quali si sono articolati i processi organizzativi nei nove comuni capoluogo. Come cioè sia avve-nuta l'integrazione tra i servizi specialistici rivolti a cittadini stranieri e il sistema dei servizi sociali generalisti. A seguito della riorganizzazione del welfare nazionale, infatti, i modi in cui i servizi si organizzano a livello territoriale è l'esito di due pro-cessi convergenti: l'integrazione tra le politiche rilevanti per il benessere dei cittadi-ni e il coordinamento dalla pluralità di attori - istituzionali e non - coinvolti o coin-volgibili nella governance di queste politiche. L'indagine copre il periodo della pro-grammazione sociale che va dal 2007 al 2017 e utilizza una base dati composta da interviste semi-strutturate a funzionari comunali e regionali (11) oltre che dai documenti amministrativi di natura progettuale e finanziaria, prodotti nell'ambito dei Paini di Zona. L'elaborazione è stata condotta utilizzando una Cluster Analy-sis sulla base di variabili ottenute attraverso la tecnica della Principal Component Analysis.
Review of Trauma and Identity in Contemporary Irish Culture, by Melania Terrazas Gallego
Authors: Lopez Nuria Del Mar Torres
Published: January 2022

Review of Trauma and Identity in Contemporary Irish Culture, by Melania Terrazas Gallego, (Oxford: Peter Lang, Re-imagining Ireland vol.94, 2020) ISBN 978-1-78997-559-8, pp. 302, €52.86
Report I of the interaction with the SRG and within WPs that have stakeholder sub-groups
Authors: Meyer Judith , Keller David P.
Published: January 2022

This report provides an overview of OceanNETs engagement with relevant stakeholders and the OceanNETs stakeholder reference group in the first 18 month of the project (01.07.2020 – 31.12.2021).
Modern systems of organization of decisions enforcement
and legal status of executors
Authors: Sergiienko Nataliia A. , Tsebenko Solomiia B. , Saienko Maryna I. , Potip Mykola M. , Dragan Olena V.
Published: January 2022

The relevance of the study is as follows: if the substantive decision of
a court or other jurisdiction (offi-cial) is subject to enforcement, the state must provide an effective mechanism for such kind of enforce-ment (otherwise, in case of non-compliance with the decision by the obligated person, protection of rights, freedoms, interests of the person will remain only on paper). An important component of such a mechanism is the system of enforcement of decisions. Therefore, each state faces the question of which system of enforcement of decisions to choose, and here we need the experience of other states that have already passed this path and can already clearly understand the results.
The purpose of the article is to consider the experience of foreign states in reforming the system of enforcement of decisions and the legal
status of executors in order to implement it in Ukraine. Methodological
basis of the scientific arti-cle is general and special methods of scientific research (deductive, analytical, synthesis method, hermeneutic method, comparative, statistical, historical, dialectical and other methods), which were used to cover the topic of the scientific
article. The results of the study contain a generalization of the experience of foreign countries in reforming the system of enforcement of decisions and the legal status of executors. The practical significance of the study is that the scientific article analyzes the application of different systems of organization of enforcement of court
decisions, other bodies (officials), different approaches to the legal regulation of the legal status of executors. This can be useful for both
legal scholars and legal practitioners, as well as anyone interested in
reforming executive legislation.
The Dialectics of the Conceptual-Categorical Apparatus of Creative Industries
Authors:   Odesa Polytechnic National University, Frolova L. V. , Koryavchenkova T. V. ,   Odesa Polytechnic National University
Published: January 2022

The article brings out the problems of unjustified equalization and fragmentary formalization of such definitions as «creative economy», «creative industries», «cultural industries», «creative product», «product of creativity». Based on retrospective analysis, it is argued that cultural industries are part of the creative industries and, correspondingly, the use of these concepts as synonyms in the economic scientific field be incorrect. On the basis of comparative analysis, the fundamental difference between enterprises of various types of economic activity in the creative economy and enterprises of creative industries was identified, which is determined by the results of creative process. It is substantiated that in the former case such a result is the product of creativity, which is a combination of creative ideas and non-standard solutions that ensure the achievement of the desired results of the enterprise in dynamic business environment and/or represents the final market product. The result of creative process in the field of kindred industries is a creative product – a specific symbolic and semantic ware, characterized not only by its economic, but also its socio-cultural value, which includes some socially significant content, is determined by the current conditions of socio-economic reality. The proposed authors’ definition of creative industries is, according to the results of the research, a sphere (type) of entrepreneurial activity based on the intellectual and creative abilities of economic interaction entities as to creation and offer of a creative product that meets the socio-cultural needs of consumers.
The Geographical Structure of Ukrainian Exports in the Face of Growing Risks of Uncertainty in the Global Economy
Authors:   State Biotechnological University, Ushakova N. G. , Pominova I. I. ,   State Biotechnological University
Published: January 2022

The article is aimed at analyzing changes in the geographical structure of Ukrainian exports in the context of increasing risks of uncertainty in the development of the global economy. The current global economy is a system where uncertainty has become one of its most important characteristics, requiring each country to find the optimal structure of foreign trade. The geographical structure of Ukraine’s exports is determined by its economic, geographical and transport-geographical position, specialization of the economy, which constitutes the basis of its export potential, established historically formed cooperation relations, position in the established markets of products sales, etc. The need to find the optimal geographical structure of Ukrainian foreign trade is caused by a negative balance of Ukraine’s trade balance; continuation of Russia’s military and trade aggression; lack of positive changes in the commodity structure of Ukrainian exports to the EU countries; increasing risks of uncertainty in the global economy as a result of the COVID-19 pandemic; decrease in revenues from export operations due to changes in the global market conditions. Currently, the markets of Asia and the Middle East are considered to be promising vectors of expansion of the geography of Ukrainian exports. The combination of economic and political aspects of foreign economic policy in expanding or reorienting the geographical structure of exports requires the search not only for the most profitable, but also, at the same time, long-term development prospects. Rising risks of global development uncertainty require an ongoing update of the sales expansion strategy. The condition for potential economic efficiency growth is not a simple increase in the number of trading partners, but a clearly defined direction of changes in the export policy of the State. Precisely these issues will be concern of the further research.
Perencanaan Ulang Tebal Perkerasan Lentur menggunakan Metode Bina Marga (Studi Kasus Ruas Jalan Piru-Waisala Seram Bagian Barat)
Authors: Metekohy Juliet Gracea , F. Talaohu Feral
Published: January 2022

Pada ruas jalan Piru - Waisala telah dibangun jalan dengan menggunakan  konstruksi  perkerasan  lentur jenis lapen. Dilihat  dari kondisi eksisting ruas jalan tersebut, diketahui telah  terdapat beberapa jenis kerusakan, diantaranya adalah lepas butiran dengan total luas terbesar 29,050 m2, kemudian kerusakan jenis berlubang dengan total luas kerusakan terbesar 0,060 m2. Hal ini disebabkan karena jalan ini telah melewati batas umur rencana dan tidak dilakukan penanganan ataupun perbaikan jalan dengan baik. Oleh karena beberapa hal tersebut maka ruas jalan tersebut tidak mampu memikul beban lalu lintas dan terus mengalami kerusakan. Untuk mengatasi permasalahan  pada ruas jalan Piru – Waisala, maka akan direncanakan peningkatan  konstruksi ruas jalan dari jenis lapen menjadi kondisi laston. Tujuan dari penelitian ini adalah untuk merencanakan kembali tebal perkerasan  lentur menggunakan dengan metode Bina Marga.. Berdasarkan  hasil perhitungan desain tebal perkerasan lentur pada daerah Piru-Waisala dengan Metode Bina Marga diperoleh lapis permukaan AC-WC dengan tebal 4,0 cm; tebal lapis permukaan AC-BC 6,0 cm; tebal lapis permukaan AC-Base dengan tebal 7,5 cm, tebal lapis pondasi atas 12,0 cm; dan tebal lapis pondasi bawah 15 cm. Sehingga dapat disimpulkan bahwa tebal lapis perkerasan lentur jenis laston yang diperoleh lebih baik dan aman sesuai perhitungan dengan menggunakan metode Bina Marga pada jalan tersebut.
ОСОБЛИВОСТІ ПРОЦЕСУ ФОРМУВАННЯ ІНСТИТУТУ ВЛАДИ КОШОВОГО ОТАМАНА ПЕТРА КАЛНИШЕВСЬКОГО
Authors: Хмельницька Людмила
Published: January 2022

У статті висвітлено політико-адміністративну діяльність останнього кошового отамана Запорізької Січі П. Калнишевського у контексті суспільно-політичних процесів в Україні ХVIII ст. Зокрема, розглянуто основні етапи формування інституту влади кошового отамана П. Калнишевського в світлі боротьби за відстоювання прав Запорозької Січі шляхом депутацій до імператорського двору та боротьби з гайдамацьким рухом. Визначено постать кошового отамана як непересічного козацького лідера, вдалого адміністратора, мудрого дипломата, що стояв на сторожі запорозьких звичаїв, прав та вольностей козацьких, був поборником ідеалів козацької свободи в непрості часи неприйняття Російською імперією самостійницьких прагнень козацтва.

Ключові слова: кошовий отаман, Запорізька Січ, козацькі депутації, гайдамацький рух, влада.
Lignocellulosic Biomass – A Sustainable Feedstock for Acetone-Butanol-Ethanol Fermentation
Authors: Mahalingam Lorianna , Abdulla Rahmath , Sani Suraya Abdul , Sabullah Mohd Khalizan , Faik Ainol Azifa Mohd , Misson Mailin
Published: January 2022

Biobutanol has been identified as a promising future biofuel. However, generally the extraction and separation of biobutanol from the fermentation mixture is a costly process. Therefore, the idea of using acetone-butanol-ethanol (ABE) mixture directly as biofuel were proposed to eliminate the recovery process. ABE has been identified as a promising future biofuel. The feedstocks play an important role in the feasibility of ABE as a fuel. Lignocellulosic biomass is seen as a promising feedstock for the production of biofuels. Thus, in this review, ABE biofuel is been summarized from three aspects namely (i) selection of feedstocks, (ii) microbial selection and (iii) hydrolysis, fermentation, and purification techniques. Anaerobic fermentation together with commonly employed recovery processes are discussed in the second part of this review. This review concludes with different challenges and future research in ABE fermentation that can pave the way for future commercialization of this promising biofuel.
Preparation of Veterinary Premix with Dual Active Ingredients in Granular Form
Authors: Fodor-Kardos Andrea , Ujhidy Aurél , Nagy Gábor , Gyetvai Béla , Tóth Judit
Published: January 2022

The aim of the study was to investigate the preparation of granular veterinary premix containing two different antibiotics by fluid bed granulation process. The particle size and density of the active ingredients were investigated for the proper selection of the filler material. The used antibiotics were tylosin tartarate and colistin sulfate, while isomalt sugar alcohol and cellulose materials were selected as filler and binder, respectively. The colistin sulfate was fed together with the binder solution because of its low density, fine particle size and relatively low (1.2%) concentration in the product. The type and concentration of the binder in its solution, the feeding rate and the total amount of added binder solution were optimized for obtaining dust free granules with desirable abrasion resistance and good flowability. The active ingredient content for both antibiotics was preserved even at the elevated temperature applied during the fluid granulation process.
Er virði í vottun?
Authors: Hróbjartsson Ari , Ingason Helgi Þór , Jónasson Haukur Ingi
Published: January 2022

Á undanförnum árum hafa mörg íslensk fyrirtæki innleitt gæðastjórnunarkerfi á grunni ISO9001 staðals og fengið vottun. Engin fjárhagsleg greining hefur verið gerð á því hvort vottun skilar íslenskum fyrirtækjum fjárhagslegum ávinningi, þó gerðar hafi verið nokkrar almennar athuganir á útbreiðslu vottunar og viðhorfum fyrirtækja til vottunar. Í þessari rannsókn eru tekin til skoðunar öll íslensk fyrirtæki með ISO9001 vottun sem störfuðu á samkeppnismarkaði og þau borin saman við sambærileg fyrirtæki sem ekki höfðu vottun, til að kanna hvort greina mætti mun á þessum fyrirtækjahópum hvað varðar ýmsar fjárhagslegar kennistærðir. Niðurstaðan er meðal annars sú að vottuðu fyrirtækin hafa hærri söluhagnaðarhlutfall og hærra eiginfjárhlutfall en þau óvottuðu.

In recent years, a number of Icelandic organizations have implemented a quality management system based on the ISO9001 standard and been certified. No effort has yet been made to analyse if certification leads to any financial benefits, yet there have been some general assessments of the distribution certified quality management systems. This paper reports from a study of all ISO9001 certified organizations in Iceland, operating in a competitive environment. They were compared to similar organizations ­ not certified ­ to assess if any differences could be found in some financial
variables between the two groups. The study shows that the certified organizations have higher return on sales and higher equity ratio.
The state of the fish farming industry and its development trends in Ukraine and the world
Authors: rofymchuk A. , Grinevich N. , Trofymchuk M. , Kunovsky Y. , Bondar O. , Tkachenko O. , Savchuk O.
Published: January 2022

The article analyzes the current state and trends of fisheries in Ukraine and the world for the period from 1996 till2020. The authors showed the changes in the extraction ofaquatic bioresources, considered the indicators of export-import operations of the industry and also considered how fishproducts were consumed by the population. The article identifies the main prospects and desirable strategies for fisheries development. Measures such as catch regulation, control over the condition of certain industrial facilities, rational ecologically balanced functioning of aquaculture and mariculture farms remain relevant for the stable supply of fish, crustaceans and other seafood to consumers. Analysis of industry trends shows that in the near future most of the world's fish stocks will be caught in steadyvolumes. In that case aquaculture will have to meet the difference between the supply of wild fish and the demand ofthe growing population of the planet. On the other hand, the development of aquaculture raises a number of issues relatedto the resources it needs and the threats posed by externalfactors, including diseases and challenges related to climatechange. The competition of technologies in the framework of sustainable development of aquaculture contributes to theimprovement of closed recirculation systems, the operationof which does not depend on climatic conditions. They alsoensure the receipt fry of fish at an early date and have proven their effectiveness in the cultivation of valuable fish species: sturgeon, catfish, tilapia, salmon. nalysis of world experience shows that the cultivationof fish in mariculture farms is optimal arrangement of largesea cages away from the shore.It is substantiated that today one of the stable ways of obtaining aquatic bioresources in Ukraine is the cultivation ofaquatic organisms in inland waters. It is expected that in thenear future in this sector will be concentrated the potential for increasing fish products and feed use.
Key words: aquaculture, fisheries, aquatic biologicalresources, fish, molluscs, crustaceans.
La gestión estratégica empresarial desde las tecnologías de la información y la comunicación. Puntos y reflexiones.
Authors: Gavilanes Sagñay Marco Antonio , Gavilanes Sagnay Fredy , Chávez Granados Nathalie Azucena
Published: January 2022

Introducción. El papel de la gerencia estratégica en las organizaciones empresariales es de gran importancia, unido a la necesidad de tener una eficiente administración de los recursos, una logística estructurada con un personal de elevada calificación, innovador, con alto grado de competitividad para incorporar la utilización de las TICs, en su actividad diaria. Objetivo.  Determinar los aspectos involucrados en la gestión estratégica empresarial desde la incorporación de las TICs, los factores determinantes y los desafíos que conlleva. Metodología. El estudio utilizó una metodología descriptiva, no experimental, basada en métodos teóricos y la revisión documental, permitiendo establecer los argumentos esenciales relacionados con el tema. Los criterios establecidos tales como: el papel de la gerencia estratégica en las organizaciones empresariales, los elementos del proceso gerencial, los desafíos de la incorporación de las TICs y los factores determinantes para la adopción de las TIC conformaron las ideas centrales de la investigación. Resultados. 1. Los estudios realizados demuestran que el liderazgo y la innovación constituyen factores concluyentes de supervivencia de las empresas. 2. Reafirma que el uso de las TICs constituye una herramienta fundamental e imprescindible para perfeccionar la Gestión estratégica. 3. Las Mipymes, tienen una inherente fragilidad por la falta de recursos, dado los continuos y acelerados cambios tecnológicos y de mercado. 4. Se precisó la importancia de los factores determinantes en la adopción de las TICs. 5. La utilización de las TICs debe formar parte del plan de negocios y corresponderse con la estrategia corporativa y organizativa de la misma. Conclusiones.  La revisión sistemática de la literatura permitió confirmar la importancia de la incorporación de las TICs como herramienta fundamental para la mejora de la Gestión estratégica de las empresas. Se aportan elementos técnicos y organizacionales, para proceder a este proceso, en función de las características de cada organización empresarial.
An Adenocarcinoma Associated with Bilateral, Diffuse, Uveal Melanocytic Proliferation
Authors: Chung Woohyun , Kim So Hee , Choi Youna , Choi Seung Kwon , Lee Jae Jung , Park Sung Who , Byon Ik Soo
Published: January 2022

Purpose: We report bilateral, diffuse, uveal melanocytic proliferation caused by a stomach adenocarcinoma.Case summary: A 78-year-old male complained of visual impairment 3 months in duration. He had diabetes and had undergone cataract surgery on both eyes 4 years prior. His best-corrected visual acuity was counting fingers in the right eye and 20/160 in the left eye. Both intraocular pressures were normal. The anterior segments yielded no specific findings. The maculae exhibited multiple, round, patchy, pigmented or depigmented lesions with exudative retinal detachment. Fluorescein angiography revealed multiple hyperfluorescent lesions. Optical coherence tomography revealed that the hyper-reflective exudates lay between the neurosensory retina and the retinal pigment epithelium. We diagnosed bilateral, diffuse, uveal melanocytic proliferation and performed a systemic evaluation. Computed tomography revealed several mass lesions in the lung, stomach, and lymph nodes; these appeared to be malignant. An esophagogastroduodenoscopic biopsy confirmed that the lesions were adenocarcinomas.Conclusions: A bilateral, diffuse, uveal melanocytic proliferation induced by a primary malignant tumor exhibited multiple, pigmented subretinal exudates associated with exudative macular retinal detachment. In patients with such findings, it is necessary to evaluate the malignant tumor status of remote organs.
Retinal Vascular Caliber Changes in Early Type 2 Diabetic Patients without Retinopathy
Authors: Park Jeong Woo , Bae Jeong Hun , Song Su Jeong , Kim Joon Mo
Published: January 2022

Purpose: To evaluate the retinal vascular caliber in early type 2 diabetic patients without retinopathy.Methods: This retrospective study reviewed the medical records of 85 patients who were diagnosed with type 2 diabetes (age, 10-48 years) and sex-matched healthy controls. Dilated fundus examinations were performed to confirm the absence of diabetic retinopathy. Fundus photographs were acquired and analyzed using software that semi-automatically measured retinal vascular caliber. Central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE), and arteriovenous ratio (AVR) were determined using the revised Parr-Hubbard formula. Healthy controls were examined using the same approach.Results: There were no significant differences between patients and controls in terms of CRAE (149.92 ± 21.29 µm and 144.85 ± 17.14 µm, respectively; p = 0.137) or CRVE (195.85 ± 22.94 µm and 196.69 ± 18.43 µm, respectively; p = 0.829). However, AVR was significantly higher in the patient group (0.768 ± 0.088 vs. 0.737 ± 0.061; p = 0.031). In the patient group, AVR was significantly correlated with hemoglobin A1c (r = 0.325, p = 0.006), but not with body mass index (p = 0.478).Conclusions: An increase in peripapillary AVR may be an early feature of retinal vessels observed in patients with type 2 diabetes, which is closely related to elevated blood sugar.
Effect of Mask Mandates on the Intraocular Pressure Measured via Goldmann Applanation Tonometry
Authors: Choi Woo Seok , Lee Chang Hoon , Lee Chong Eun , Seo Sam , Lee Kyoo Won
Published: January 2022

Purpose: The corona virus disease-19 (COVID-19) pandemic has resulted in mandatory masking of patients and physicians during outpatient visits. This study evaluated the changes in intraocular pressure (IOP) according to mask use.Methods: This prospective study enrolled 30 healthy volunteers (60 eyes). IOP was measured via Goldmann applanation tonometry (GAT) for the subjects wearing one of four commonly used masks: dental, bi-folding Korean Filter (KF)94, tri-folding KF94, and dust masks. Subjects with IOP measurement errors of more than 5 mmHg were rechecked with another GAT type.Results: The mean IOP measured via GAT before mask wearing was 13.7 ± 1.7 mmHg. It was 13.5 ± 2.1, 14.0 ± 2.3, 14.3 ± 2.5, and 13.8 ± 1.6 mmHg with the dental, bi-folding KF94, tri-folding KF94, and dust masks, respectively. There were no significant differences in IOP according to mask type (p = 0.635). IOP errors above 5 mmHg were detected in three subjects who had contact between the GAT feeler arm and tri-folding KF94 mask during IOP measurement.Conclusions: The IOP as measured via GAT is artificially elevated by mechanical interference from the tri-fold KF94 mask. To minimize such mask-induced artifacts in GAT measurements, compress the patient’s mask or change the mask type to prevent any contact during measurement.
Predictive Value of Malignancy Index in Tumour Staging in Prostate Cancer
Authors: Serafin Antonio M. , Chinhengo Angela , Akudugu John M.
Published: January 2022

Background: A fine balance exists between the early treatment of a potentially lethal prostate disease and possible complications from the early treatment of a potentially indolent disease. Prostate-specific antigen (PSA) is an indicator of disease progression and is used in the clinical staging of prostate cancer (PCa). Given the arsenal of staging methods available, some intrusive, some not, is there a future for biochemical staging? As the presence and stage of disease are influenced by multiple factors, it is conceivable that an effective biomarker for determining pathology and stage could require a convolution of more than one biochemical entity. In this study, the authors introduce a malignancy index capable of staging PCa and discriminating pathology from non–pathology, in three unmatched sample types.

Methods: Total protein measurement was by means of the Pierce Bicinchoninic acid protein assay. The total PSA concentrations were measured using a microparticle enzyme immune assay, and ELISAs confirmed the urokinase plasminogen activator and plasminogen activator inhibitor–1 concentrations. The three markers (PSA, urokinase plasminogen activator, and plasminogen activator inhibitor-1 as well as patient age) were used in the formulation of a malignancy index (the degree of a person’s vulnerability to disease).

Results: The authors examined the robustness of their malignancy index in transurethral resection and biopsy tissue and plasma samples and proved that it discriminated PCa from non–PCa and was able to predict tumour stage.

Conclusions: The malignancy index in this preliminary research increases with disease stage (T1 through T4) and deserves some attention as a credible marker.
Current Therapy in Inflammatory Bowel Disease: Why and How We Need to Change?
Authors: Falloon Katherine A , Fiocchi Claudio
Published: January 2022

During the last few decades, major progress has been made in the treatment of the two major forms of inflammatory bowel disease (IBD): Crohn’s disease and ulcerative colitis. However, the success of the most advanced forms of therapy is at best 50%, and most patients lose responsiveness with time and need to switch to alternative medications. This denotes that a therapeutic ceiling has been reached and brand new approaches are badly needed. This commentary first briefly reviews current and recent therapeutic approaches for Crohn’s disease and ulcerative colitis, pointing out their limitations. This is followed by an objective evidence-based discussion of why the current approaches are far from optimal, and the commentary is concluded by proposing how to change IBD treatment based on the holistic concept of network medicine, and how to implement precision medicine for IBD using artificial intelligence-based multi-omics analyses.
The Kaʿba as Navel
Authors: O'Meara Simon
Published: January 2022

This chapter concerns the Kaʿba as the Islamic world’s omphalos: its axis and generative matrix. It seeks to understand how the Kaʿba is said to orient the world and what it is about the Kaʿba that makes this orientation empirically conceivable. Divided into two parts, the first part reveals that the Islamic world is said to be oriented to the Kaʿba because it is generated from the Kaʿba. The second part shows that the Kaʿba has this world-orienting capacity because it is construed as having the attributes of a bifurcated, bilateral body.