bluuebunny/crossref_metadata_2025 huggingface dataset:
Clima institucional y calidad de gestión educativa en las Instituciones Educativas del Nivel Primario de la provincia de Padre Abad, Ucayali -2019
Authors: Rivera Samaniego Kely Janeth , Mamani Flores Manuel , Pari Quispe Dina
Published: November 2021

The relationship between the institutional climate and the quality of educational management was determined. To this end, 171 surveys were carried out using a questionnaire and a cross-sectional approach, and the data was compiled. The dimensions used to determine the institutional climate were leadership, decision-making, work commitment, work satisfaction and teamwork. To measure the quality of educational management, curricular, administrative, organizational and communicative pedagogy were used, thus obtaining the relationship between leadership, decision-making, work commitment, work satisfaction and teamwork, where the value of r was 0. 39 (p-value = 0.000; p<0.05), 0.393 (p-value = 0.000; p>0.05), 0.588 (p-value = 0.000; p<0.05), 0.567 (p-value = 0.000; p<0.05) and 0.351 (p-value = 0.000; p<0.05) respectively at a 95% confidence level. These results show us that there is a relationship between leadership, decision making, work commitment, work satisfaction, and teamwork with the quality of educational management.
Sistema de monitoreo basado en ELK Stack para mejorar el gobierno de TI
Authors:   Universidad Nacional de Ucayali, Barahona Cotarate Angelo Bryan , Rodriguez Zevallos Katherin Vanessa , Escobedo Bailón Frank Edmundo
Published: November 2021

Currently, monitoring tools in the market help to maintain in optimal conditions the IT infrastructure and thus improve the IT management of an organization providing a strategic alignment. Objective: The objective of the study is to analyze how to respond quickly to incidents that originate in IT resources, through a monitoring system based on ELK Stack, leading to an improvement in IT governance within the organization. A review of different sources of bibliographic documents no older than 5 years and with articles described as research was made. Within IT governance, a monitoring tool based on ELK Stack generates flexibility by generating reports with clean data and facilitates decision making through dynamic dashboards. ELK Stack being an Open Source framework, divided into 3 tools with different purposes, prioritizes the adaptation of adequate monitoring to an organization's plans with IT. The implementation of a monitoring system not only improves the response time to incidents, but also improves the performance of personnel at the operational level and at the managerial level.
Nuevas tendencias para la optimización de los procesos de Inteligencia de Negocios
Authors:   Universidad Nacional de Ucayali, García Jara Rosa Mirelly , Gutiérrez Villanueva Katty Susana , Rodríguez Zevallos Katherin Vanessa , Escobedo Bailón Frank Edmundo
Published: November 2021

Business Intelligence is becoming more and more relevant in companies, this is due to the fact that decision makers rely on it to perform the work itself. Based on this assertion, it is necessary to facilitate the BI process, reducing response times and increasing effectiveness and efficiency. This article shows different ways to perform Business Intelligence, from the origin, i.e. the extraction of data, to the last link of the process related to decision making. To this extent, new alternatives are presented that with the necessary study have shown that they go beyond what we now know as BI, allowing not only to make decisions but also to propose that these have an automated support, also allowing the data to be processed practically alone and to handle more real reports based on data from various sources. The objective of the study is to analyze the new trends for the development of processes related to business intelligence, for which a meticulous bibliographic review has been carried out by consulting scientific articles, books and scientific conferences. First, the description of terms and the staging of the information collected through the research, dedicated to the various innovative trends for the deployment of Business Intelligence, showing new definitions, architectures and trends that are currently being carried out, have been developed. Finally, SOA architecture proposals, open data acquisition, process automation and data warehouse reengineering would allow the optimization of business intelligence through their alternatives.
ANALYSIS OF THE IMPACT OF SURAMADU BRIDGE DEVELOPMENT TO THE ECONOMIC GROWTH OF ITS CORE AND PERIPHERY REGIONS
Authors: Liza Setya Eka Hasul  , Ari Dwi Jayanti
Published: November 2021

East Java is one of the provinces in Indonesia which economic growth is above the national average. The city of Surabaya is the biggest contributor to the economy of East Java. Approximately 24% of the GDRP of East Java comes from this city. Although Bangkalan Regency is one of the bordering regencies of Surabaya, its economic growth is relatively low compared to the other bordering regencies. One of the government efforts to reducethe regional inequality is by building the Suramadu Bridge. According to the polar theory of growth, there are two possibilities that may occur as a result of regional interconnectivity. The first is centrifugal force which drives the population and its activities to move out of the core area followed by relocation of urban sectors and zones. The second is centripetal force which encourages population and activities to move towards the centeror core. The objective of this study is to assess the impact of the construction of the Suramadu National Bridge on economic growth in the core and periphery regions. Using Difference-in-Difference method, we found that the impact of the construction of the Suramadu Bridge on economic growth was greater in the periphery area than in the core area. This result might also imply that the development of Suramadu Bridge also resultedin the formation of centrifugal force which encouraged the economy to develop from the core to the periphery.

JEL : R1, R4, O4, I1, I2
THE EFFECT OF FORMAL SECTOR WORKERS AND WOMEN HEAD OF HOUSEHOLDS ON WELFARE IN EAST JAVA
Authors: Purwaningsih Vitriyani Tri , Nida Rahma
Published: November 2021

Isu ketidaksetaraan dalam gender tidak hanya dilihat dari bentuk fisik yang berbeda, akan tetapi kesenjangan tersebut mengarah pada perbedaan peran, kegiatan, serta hal lainnya yang terjadi di kehidupan sehari-hari. Rumah tangga yang dipimpin oleh perempuan cenderung lebih banyak berkerja pada sektor informal, memiliki tingkat pendidikan dan pendapatan yang rendah. Penelitian ini bertujuan untuk melihat kesenjangan antara pekerja formal dan informal, kesejahteraan rumah tangga yang diukur dari kepala rumah tangga berdasarkan gender dan status pernikahan. Data yang digunakan merupakan data sekunder yang berasal dari Indonesia Family Life Survey (IFLS) tahun 2014, dengan analisis Two Stage Least Square (2SLS) dengan menggunakan Instrumental Variable (IV). Temuan dari penelitian ini menyatakan bahwa Kepala Rumah Tangga (KRT) yang bekerja di sektor formal mempunyai kesejahteraan yang lebih tinggi dibandingkan dengan KRT yang bekerja di sektor informal. Selain itu, KRTP cenderung mengalami probabilitas untuk mengalami kerugian dibandingkan KRTL. KRTP yang berstatus janda memiliki kesempatan yang lebih besar untuk menjadi miskin dibandingkan dengan kelompok lainnya. Di sisi lain, adanya hubungan positif dan signifikan antara wanita pekerja informal terhadap pengeluaran per kapita. Kesimpulan untuk kebijakan dari permasalahan dalam penelitian ini adalah pemerintah Jawa Timur perlu memperhatikan pilar utama pembangunan manusia yaitu dengan mengurangi gap pendidikan, khususnya bagi anak perempuan.

JEL : D63, I31, J12, J16, O17
INFECÇÃO DE CORRENTE SANGUÍNEA ASSOCIADA AO USO DE PICC EM NEONATOS: CONHECIMENTO DE GRADUANDOS DE ENFERMAGEM SOBRE OS FATORES RELACIONADOS E ESTRATÉGIAS UTILIZADAS PARA A PREVENÇÃO
Authors: Motta Figueredo da Silva Isabelly , Xavier Moreira da Silva Maria Aparecida , Losano Pais Barbosa Gabriela
Published: November 2021

Introdução: Este estudo busca obter maior conhecimento sobre as ações e estratégias utilizadas pelo enfermeiro para a prevenção de Infecção de Corrente Sanguínea associada ao uso de PICC em neonatos. Objetivo: O objetivo do estudo é descrever o conhecimento dos graduandos de enfermagem sobre os fatores relacionados à ICS associada ao uso de PICC em neonatos e as estratégias utilizadas para a prevenção. Método: Trata-se de uma pesquisa descritiva, transversal e com abordagem qualitativa que foi realizada com graduandos de enfermagem do 6º ao 10º período do Curso de Graduação em Enfermagem da Universidade de Mogi das Cruzes, em São Paulo, Brasil. Resultados e discussão: Para compor este estudo, os dados sociodemográficos foram coletados para entendermos melhor o público participante. Foram convidados 22 graduandos do curso de enfermagem ao todo, sendo 81,82 do sexo feminino, e 18,18% do sexo masculino, com idade variadas, de até 25 anos (68,18%), 25 a 35 anos (18,18%), 35 a 45 anos (9,09%) e de 45 anos em diante (4,55%). Conforme os resultados obtidos por meio de questionário separado por temáticas, salientamos que, os alunos entrevistados demonstraram concordância com  que diz a literatura sobre a importância da capacitação para passagem e manutenção do PICC e demais cuidados que objetivam a prevenção de ICS associada, não estando restrito somente ao enfermeiro, mas também a toda equipe de enfermagem que está envolvida diretamente no cuidado. Conclusão: Os dados coletados e seus respectivos resultados demonstram um conhecimento satisfatório dos graduandos sobre as questões aplicadas, mostrando que o objetivo deste estudo foi alcançado. Uma limitação deste estudo foi a escassez de pesquisas realizadas com graduandos do curso de enfermagem em relação ao uso de CCIP em recém-nascidos, visto que em sua maioria as pesquisas relatadas são realizadas com profissionais já graduados, mostrando uma realidade e perspectiva distinta.
Publish or Perish: no longer just a buzzword
Authors: Fenner Martin
Published: November 2021

Google Publish or Perish is a new science writing tool that facilitates paper submissions. The tool was field-tested at the NIH and should be particularly valuable for open access and public access journals. Accepted papers are automatically added to your Researcher ID account. For more information, read this forum post by Matt Brown.
Relationship between Teachers’ Competency Level in Teaching English Language and Students’ English Language Proficiency in Secondary Schools in Rwanda
Authors:   Mount Kenya University, Serge Girimbabazi , Oyebimpe Mrs Adegoke ,   Mount Kenya University, Andala Dr. Hesbon Opiyo ,   Mount Kenya University
Published: November 2021

The improvement of students’ English proficiency depends on the level of teaching English language and the competency of teachers in teaching career. The purpose of this study therefore, was to investigate the relationship between teachers’ competency in English language and students’ English language proficiency within secondary schools of Karongi in Rwanda. The study adopted correlation research design research design. Data collection tools were questionnaire and interview guide. The target population was 1794 people comprised of 1560 students, 14 Sector Education Officers, 20 Head Teachers, 200 teachers. A simple random sampling and purposive sampling techniques were used to get a sample size of 395 respondents. The study findings revealed that majority of the students with a total of 290 (91.2%) agreed that in their school, teachers are not competent enough in English language. Moreover, almost 292 (91.8%) of the respondents agreed that in their school, students English reading, writing, listening and speaking proficiency level is low and 70 (90.9%) of key informants agreed that both in public and private secondary schools of Karongi District, students’ English language proficiency level in reading, writing, speaking and listening is low. The correlation results showed the association between between teachers’ inability to teach in English, teachers’ inability to read classroom interactions in English language, teachers’ incompetency in English language, teachers’ inability to express themselves in English language as well as teachers’ inability to develop English language educational materials) and dependent variables (students’ reading, writing, speaking and listening English language proficiency and students’ English language proficiency (reading, writing, speaking and listening English proficiency) is positive. The study recommended the Ministry of Education through Rwanda Basic Education Board to avail enough English teaching and learning materials, including charts, textbooks and dictionaries which are adequate in enhancing English language proficiency mastery among students at an early age. All stakeholders of the education sector are recommended to support English teaching and learning activities in Rwanda, as it is the only and one shortcut for making Rwandans master the English language. Keywords: Teachers’ competency, English Language, English proficiency, Rwanda
Pedagogía verde para la formación de seres crí­ticos y reflexivos
Authors:   Universidad Tecnológica Indoamérica, Duque Romero Marco Vinicio , Cadena Bastidas Karla Paola ,   Universidad Tecnológica Indoamerica
Published: November 2021

The advancement of science and technology has modified the lifestyle, implanting superficial recreation sites away from the natural environment, education must center the student within the natural context to generate environmental awareness and form critical and reflective beings. Present real alternatives that promote interaction with the natural environment and generate meaningful learning. This article was based on qualitative research through a bibliographic review, the most relevant articles were selected, the results were obtained from indexed journals, mainly in Google Scholar. Green pedagogy aims to transform the social and cultural context by adding nature as the central axis of education; For this, various researchers present real alternatives to bring the natural environment closer to the social one, trying to contrast the damage caused to the planet. Several researchers try to generate environmental awareness, analyze the socio-historical context and present alternatives that stop the damage caused to the Earth, to produce a significant change within society, for this it is necessary to intervene in education and to shape actions, thoughts and ways of proceeding of students in a conscious, direct and real way.
Tutoría académica en la educación superior: el rol del autor académico, tutor pedagógico y del estudiante en la modalidad a distancia
Authors:   Universidad Tecnológica Indoamerica, Núñez Naranjo Aracelly Fernanda
Published: November 2021

Academic tutoring constitutes a pedagogical practice that allows the construction of knowledge for the different actors involved in the process, thus, this work reflects on academic tutoring in higher education, in education careers with a distance modality, made up of three subjects, the academic author, the pedagogical tutor and the student. This analysis, based on a set of questions about each of the different roles, as well as mentions the realities located, the purpose in the environment and virtual social environment and identifies four dimensions, the pedagogical, the administrative, the technological and the social, which are involved in the process of teaching and learning, which has as its purpose to learn to understand, learn to be, learn to live together, learn to act and learn to decide approaching reality as an actor in your role and enabling autonomous and collaborative work. Academic tutoring requires a process of reflection on the goal of personal formation, deepening of the role, identification of the needs of students, academic goals, emotional aspects in which the dimensions facilitate the teaching and learning process.
COMPARATIVE EFFECT OF CRUDE EXTRACT OF PARKIA BIGLANDULOSA AND ITS ISOLATE ON REGENERATIVE ANGIOGENESIS IN ADULT ZEBRAFISH MODEL
Authors: Shete S. V , Mundada S. J. , Dhande S. ,   Department of Pharmacology, Bharati Vidyapeeth’s College of Pharmacy C.B.D. Belapur - 400 614, Navi Mumbai, Maharashtra, India.
Published: November 2021

As cancer continues to be one of the biggest threats worldwide and causes maximum deaths after cardiovascular diseases, a greater emphasis must be given for newer strategies for the development of anti-cancer drugs. Cancer treatment strategies target various mechanisms such as apoptosis, metastasis, angiogenesis, etc. Angiogenesis, which is the process of generation of new capillary blood vessels, can be an excellent target for anti-cancer therapy, as a tumor cannot grow further without it. The present study aims to evaluate and compare anti-angiogenic activity of ethanolic extract of Parkia biglandulosa (EEPB) and its isolate β-sitosterol by regenerative angiogenesis assay using caudal fin of adult zebrafish. One of its active constituents that is β-sitosterol, which was expected to show anti-cancer activity, was isolated by using flash chromatography and its activity was checked along with crude ethanolic extract of Parkia biglandulosa (EEPB). Results of regenerative angiogenesis compared by one way ANOVA followed by Tukey’s test showed significant inhibition of fin growth when compared with control group which signified anti-angiogenic effect of test compounds.
SYNTHESIS, CHARACTERIZATION, CATALYTIC AND BIOLOGICAL APPLICATIONS OF SILICA SUPPORTED COPPER NANOPARTICLES
Authors: Kshirsagar S. S. , Shinde V. R , Suradkar S. B. , Jadhav A. V. , Bhujbal N. S. ,   Kasturi Shikshan Sanstha College of pharmacy, Pratima Nagar, Pune-Nagar Road Shikrapur, Shirur, Pune - 412 208, Maharashtra, India.
Published: November 2021

Various metal nanoparticles have been synthesized which are used in chemical as well as medicinal industry, but many of them are associated with problems. Hence, there is a need to develop a method for the synthesis of metal nanoparticles with fewer problems. Synthesized Cu/SiO2 nanoparticles have been characterized by XRD, SEM and EDS analysis. Further, their catalytic activity was estimated by various chemical reactions. Antibacterial activity, cytotoxic activity against breast cancer cell lines, acute toxicity and blood biochemical assay were determines. Particles size of Cu/SiO2 was found to be within 20-50nm. Synthesized nanoparticles were catalytically active in performed chemical reactions. Cu/SiO2 was found to be an active antibacterial against gram positive and gram negative bacteria. Acute toxicity and blood biochemical assay help to conclude that the synthesized nanoparticles are non-toxic.
NARINGIN ATTENUATES METHOTREXATE INDUCED INTESTINAL INJURY AND OXIDATIVE STRESS IN WISTAR RATS
Authors: Karale S , Kamath J. V. ,   PRIST University, Vallam, Thanjavur – 613 413, Tamil nadu, India.
Published: November 2021

Methotrexate (MTX) is a pivot anticancer drug used for cancer therapy, rheumatic disease and psoriasis. Intestinal damage is a main toxic effect of MTX associated with villus shortening, mitotic arrest in crypt, atrophy of epithelium, disruption of mucosa, inflammation, ulcer and decline in goblet cells. The aim of present study was to investigate the protective effect of naringin on MTX induced intestinal injury and oxidative stress in wistar rats. The animals were randomly divided into five equal groups: Normal (saline 1 mL p.o.), MTX (20 mg/mg i.p on 4th day), Group III (Naringin 50 mg/kg p.o., + MTX 20 mg/kg, i.p.), IV (Naringin 100 mg/kg p.o., + MTX 20 mg/kg, i.p.) and V (Naringin 100 mg/kg p.o., alone). Rats of all groups except Group I and Group V treated with MTX in a dosage of 20 mg/mg i.p on 4th day. Jejunum tissues of each rat were isolated and subjected to antioxidants evaluation such as myeloperoxidase (MPO), glutathione peroxidise (GP-x), malonyl dialdehyde (MDA), glutathione (GSH), super oxide dismutase (SOD), catalase and histopathological study. Naringin exhibit a significant (P<0.001) protective role against MTX induced intestinal oxidative injury by elevating the GSH, SOD, catalase and suppresses the MPO and MDA level. Also, naringin successfully prevents the MTX treatment induced villus shortening, crypts damage, inflammatory infiltration, ulceration and depletion of goblets cells in experimental rats. The current findings demonstrate that naringin explored beneficial role by attenuating the MTX induced impairment in oxidative stress and jejunum injury in rats.
CHEMICAL EXAMINATION OF CHLOROFORM FRACTION OF CLEOME FELINA L. F.
Authors: Manjuparkavi K. , Jayanthi G ,   PG and Research Department of Botany, Vellalar College for Women (Autonomous), Erode - 638 012, Tamil Nadu, India.
Published: November 2021

The present investigation, the phytochemical composition of the chloroform fraction of Cleome felina L.f. by Gas Chromatography Mass Spectroscopy (GC-MS) analysis revealed totally 30 constituents. The major constituents are octadecane, 9-octadecenamide, (z)- , 2-tert-butyl-4-isopropyl-5-methylphenol, hexadecane, dodecane, 1-iodo-, tricosane, 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23- hexamethyl-, (all-e)-, 3-Tetradecene, (z)-, decane, 2-methyl- , 1,2-benzenedicarboxylic acid and bis(2- methylpropyl) ester.
HPLC METHOD FOR ESTIMATION OF GALLIC ACID AND EMBELIN IN AVIPATHI CHOORNAM- AN AYURVEDIC FORMULATION
Authors: Jadhav A. P. , Mali S. D. ,   Department of Quality Assurance, Bharati Vidyapeeth’s College of Pharmacy, C. B. D. Belapur- 400614, Navi Mumbai, Maharashtra, India.
Published: November 2021

In the present study, an attempt has been made to develop an analytical method for the simultaneous estimation of gallic acid and embelin in marketed Ayurvedic polyherbal formulation Avipathi choornam by High Performance Liquid Chromatography (HPLC). The chromatographic separation was performed on Hemochrom C18 column (250 mm L × 4.6 mm ID column: packing size- 5 μm) with a mobile phase methanol: phosphate buffer pH 3.3 (adjusted with glacial acetic acid) in 75:25 V/V proportion at flow rate of 0.8 mL/min. The analysis was carried out in the absorbance mode at 291 nm. Gallic acid and embelin were satisfactorily resolved with Rt values at 2.36 min and 6.67 min, respectively. The developed method was found to be simple, precise and accurate and can be useful for the quality control of raw material as well as formulations containing these phytoconstituents.
PREDICTING POTENT ANTIHYPERTENSIVE COMPOUNDS OF PYRIDINE DERIVATIVES BY MOLECULAR MODELING APPROACH
Authors: Sharma M. C. , Kohli D. V ,   School of Pharmacy, Devi Ahilya University, Khandwa Road, Indore - 452 001, Madhya Pradesh, India.
Published: November 2021

A quantitative structure activity relationship study was performed on a series of pyridine substituted compounds as angiotensin II receptors for establishing quantitative relationship between biological activity and their physicochemical structural properties. Partial least square (PLS) methodology coupled with stepwise forward backward method were applied to derive QSAR models, which were further validated for statistical significance and predictive ability by internal and external validation. A 2D QSAR model was generated with correlation coefficient (r2) of 0.8874, significant cross-validated correlation coefficient (q2) of 0.7498, r2 for external test set (pred_r2) 0.7869. A Zscore_r2 value of 3.9853, Zscore_q2 value of 2.8642 and Zscore_ pred_r2 value of 1.0583 statistically validates the significance of the obtained QSAR model. Molecular field analysis (MFA) was used to construct the best 3D-QSAR model showing good correlative and predictive capabilities in terms of q2= 0.7264 and pred_r2= 0.6988. The quantitative structure activity relationship study provides important structural insights in the designing of potent antihypertensive molecules.
STUDY OF KEY STAKEHOLDERS FOR THEIR KNOWLEDGE, ATTITUDE AND PRACTICE ON ADVERSE DRUG REACTION REPORTING IN TERTIARY CARE HOSPITALS IN JAIPUR, INDIA
Authors: Sharma R. ,   IIHMR University, Jaipur- 302 029, Rajasthan , India.
Published: November 2021

Adverse drug reactions (ADR) are the leading cause for the hospital administration, morbidity, and mortality as per the established data. Present pharmacovigilance program of India is performing well for strengthening ADR reporting system. The current project is aimed to study knowledge, attitude and practices of health care professionals and key stakeholders for adverse drug reaction reporting of marketed medicines. The study was conducted in four major tertiary care hospitals in Jaipur from government and private sector from May to July 2015. The data was collected from key stakeholders with a sample size of 1022 (male & female of age group 18-70 years) using a semi structured questionnaire tool separate for different segment of the key stakeholders. Data was cleaned and analysed for its descriptive report and assessment of the situation. There is less aware of the adverse drug reaction reporting system, only 32% of the doctor’s sample is aware about the reporting system of adverse drug reaction in India as well as the mandatory time period in case of serious adverse drug reaction reporting (26%). The location for regional office for adverse drug reaction reporting is known to only 26% of the sampled doctors in all the major four tertiary care hospitals of Jaipur. It is found that the awareness about ‘To whom adverse drug reaction should be reported’ is seen in only 12% of the sample doctors. While only 6% of them are provided any training about the adverse drug reaction reporting procedure. It was found that only 57% of the sampled doctors had encountered patients with adverse drug reaction in their clinical practice during last one year of the study, and only 45% of them are recording adverse drug reactions in their record book or file. It was found that although the health professionals are aware of the basic knowledge about the adverse drug reaction due involvement of key terms in their basic education and training, there is a huge gap found in knowledge parameter as seen in unawareness about the reporting system of Pharmacovigilance.
NEW ALIPHATIC CONSTITUENTS FROM THE AERIAL PARTS OF ARTEMISIA ANNUA L.
Authors: Singh V. , Goel R. , Rajkumari  , Ali M. ,   School of Pharmacy, Sharda University, Greater Noida - 201 306, Uttar Pradesh, India.
Published: November 2021

Artemisia annua L. (Asteraceae) is an aromatic annual herb, up to 2 m in height, found in temperate Asia, especially China and naturalized in many countries of the world. The plant is prescribed against fever, malaria, skin diseases, jaundice, malignant ulcers and haemorrhoids. Phytochemical investigation of the aerial parts of A. annua led to the isolation of alkyl alcohols, fatty acid esters, alkyl glucoside and fatty acids characterized as n-nonadecan-2-ol (1), n-heptadecanyl n-octadec-9,12-dienoate (2), n-octacosanyl alcohol (3), n-nonacosanyl n-octadec-9,12-dienoate (4), n-cos-(Z)-10-enoic.acid (5), nheptadecanyl- β-D-glucopyranoside (6), n-docosan-9β-ol (7), n-cos-(Z)-9-enoic acid (8) and n-octadecanyl, n-octadec-9,12,-dienoate (9). The structures of all phytoconstituents, isolated for the first time from A. annua, have been elucidated on the basis of spectral data analysis and chemical reactions.
INTERDISCIPLINARY COLLABORATIVE RESEARCH: AN IMMEDIATE NEED IN TODAY’S PHARMACEUTICAL RESEARCH
Authors:   Editor, Indian Drugs., Nair Gopakumar G.
Published: November 2021

Dear Reader, While India has acquired global recognition as a reliable source of high quality, impurity free active pharmaceutical ingredients (APIs) and generic pharmaceuticals, Indian pharmaceutical R&D has to go a long way to enter the global pharmaceutical R&D map. The 2016 OECD report “Measuring Science Technology and Innovation” (https://www.oecd.org/sti/STI-Stats-Brochure.pdf) has a large compilation of data on R&D. India hardly finds a place in this study, except on the use of the internet & IT.As confirmed by the OECD data in 1960, 70% or more of all R&D spend globally was from Government funds. India claims to have the largest chain of R&D laboratories in the world under the CSIR/DSIR umbrella. Between 1960 to 2017, the contribution of CSIR laboratories,including once-reputed laboratories such as CDRI, Lucknow and IIIM, Jammu, to pharmaceutical research has only gone down.
GÖÇ AKIŞI VE MUTLULUK ENDEKSİ: G7 ÜLKELERİ ÜZERİNE GÖÇ ANALİZİ (2006-2019)
Authors: ÇİPE Bilge , USANMAZ Dilek
Published: November 2021

İnsanoğlu tarih boyunca çeşitli nedenlerden dolayı sürekli mekân değişikliği yapmıştır. Göç etmek fiiline karşılık gelen bu hareketliliğin nedenleri her dönem değişmektedir. Örneğin bundan beş yüzyıl önceki insanların göç nedeni bugünkü göç nedenlerinden çok farklıdır. Değişen yaşam koşulları ve küreselleşme ile göç hareketleri daha hızlı ve daha geniş kapsamlı olmaktadır. Bugün insanların yaşadığı mekânlardan göç etme sebeplerinden en önemlisi düzgün hayat şartları, geniş sosyal olanaklar ve özgürlüktür. İşte bu sebepler, son yıllarda iktisatçılar tarafında çekici bir konu haline gelen “mutluluk” kavramına denk gelmektedir. Artık ülkeler refah seviyelerini sadece iktisadi dayanaklara değil aynı zamanda ülke insanlarını mutlu kılan etkenlere göre de ayarlamaktadır. Sosyal politikaları genişletmek ve daha yararlı hale getirmek için mutluluk endeksi verilerinden faydalanılmaktadır.

Bu çalışmada hem sürekli ve artan bir şekilde göç alan ve aynı zamanda mutluluk seviyeleri her zaman üst düzeyde olan G7 ülkeleri araştırılmıştır. “İnsanlar göç kararı alırken gideceği ülkenin mutluluk endeksi verilerinden ne derece etkilenmektedir?” sorusunun yanıtı araştırılmıştır. Yapılan ampirik analizlere göre insanlar, bir yerden bir yere göç ederken (savaş, doğal afet, terör gibi zorunlu etkenler hariç) gideceği ülkenin hayat şartlarına, iş olanaklarına, eğitim, sağlık gibi sosyal haklarına, özgür yaşam biçimine ve ülke yönetiminin yerli olmayan halka sunduğu olanaklara göre karar vermektedir.
Analyzing the Effects of CLIL Method in Teaching Business English Writing in China
Authors: Rong He , Nair Subadrah Madhawa
Published: November 2021

The use of CLIL (Content and Language Integrated Learning) teaching method in English writing proved to be efficient in enhancing students’ language and content knowledge. This study aims to explore the effects of utilizing CLIL method in teaching Business English Writing among Chinese college students. A quasi-experimental design was adopted. The experiment lasted for a total of eight weeks. The Experimental Group was taught Business English Writing using CLIL method while the Control Group was instructed with the conventional method. The sample of the study consists of 80 third year Business English college students from Shaoyang University in Hunan Province, China. Two classes of students were chosen as intact group sampling (40 students in each group). A pre-test and post-test were used as instruments. The data was analyzed using Independent samples t-test. Prior to the actual study a pilot test was carried out to obtain the reliability and validity of the instrument (writing test). The findings from quantitative data showed that students of the Experimental Group using CLIL teaching method performed significantly higher in their overall Business English Writing, report writing, memo writing, letter writing than students in the Control Group using conventional method. Therefore, it can be concluded that the CLIL principle should be employed as an alternative method in future writing classes. These findings have significant pedagogical implications because the CLIL method facilitated students to improve in their Business English writing skills.
Analyzing Descriptive Writing among Chinese Undergraduates According to Gender
Authors: CHEN Qian , Nair Subadrah Madhawa
Published: November 2021

The aim of the study is to assess the Chinese undergraduate students’ EFL descriptive writing ability according to gender and to explore four EFL lecturers’ views on how to help students enhance their EFL descriptive writing. This study employed descriptive research design using the QUAN-qual model. A descriptive writing test was used as an instrument and the essays of the students were marked by a lecturer. Purposive sampling was used to select samples which consists of 400 Chinese undergraduate students (200 males and 200 females) from Hunan City University in Hunan Province, China. Before the actual study, the researcher carried out a pilot test to investigate the reliability and validity of the instrument (descriptive writing test). The results obtained from the quantitative data showed that female students outperformed male students in their overall writing as well as each component of the writing. In relation to students’ writing level, the lecturers emphasized that it is very crucial to utilize the Process Approach in class to enhance students’ vocabulary and grammar foundation. In addition, students are required to practice writing more frequently which can arouse their enthusiasm in learning English.
IMPLEMENTASI METODE KOLASE DALAM MENINGKATKAN MOTORIK HALUS ANAK USIA DINI
Authors: Suseni Made , Arini Ni Made , Sasmika Dewi Ni Putu
Published: November 2021

Improve Early Childhood Education, teachers must have high creativity in delivering material using methods that make children motivated to learn. One of them is the collage method which aims to improve fine motor skills in early childhood. This study uses qualitative and descriptive methods with data collection techniques by triangulation, observation, interviews, and documentation. The collage method applied at Cahaya Ananda Kindergarten uses various media such as paper, seeds, cotton.
IMPLIKASI POLA ASUH ORANG TUA DALAM PENUMBUHKEMBANGAN KARAKTER ANAK USIA DINI
Authors: Sunariyadi Nyoman Sri , Yuni Andari Ida Ayu Made
Published: November 2021

Parenting patterns to develop children's character education require extra coaching and supervision efforts by parents. So it is necessary from the character education needed by children. In this study using descriptive research with qualitative methods. In the research conducted in Ubung Kaja Village, it was found that parents instill the character of tolerance from children from an early age, parents also instill a communicative character in socializing with others and instill the value of religious teachings, namely Tri hita Karana by increasing the character of caring for the environment by watering plant.
SEKAR RARE SEBAGAI MEDIA PEMBELAJARAN NILAI ETIKA HINDU DI PENDIDIKAN ANAK USIA DINI
Authors: Wiasti Ni Komang
Published: November 2021

Dharmagita is a sacred religious song that is sung during religious ceremonies. Within a specific scope, Dharmagita can be sung at the level of formal, non-formal and informal education. Because the benefits are very important for Hindus, and even used to accompany dances that are profane and sacred, children's play, and even worship to Ida Sanghyang Widhi wasa. Sekar rare as a children's song that has a cheerful character, as an accompaniment to children's games today needs to be raised from an early age to an adult level, with the aim of fostering social sensitivity, courtesy, sradha bhakti, as Hindu ethical values. In reality, it is rarely used by PAUD teachers because of the lack of references, and they are still focused on implementing a complete curriculum, so it needs to be awakened. Therefore, it is necessary to study about sekar rare as a medium for learning Hindu ethical values in PAUD. The method used in the meaning of rare sekar is qualitative descriptive. Data analysis refers to interpretive data and facts. There are several Hindu ethical values contained in Dolanan, Gending Janger, and Gending Sanghyang, namely divine values, compassion values, national values, sradha bhakti values, and social values.
Pandeminin Gölgesinde; Çocuk Sağlığı
Authors: GÜLLÜ Fehime Nida , TÜMER Adile
Published: November 2021

COVID-19 pandemisi hızlı yayılım gösteren ciddi bir halk sağlığı sorunudur. Geliştirilen politikalar doğrultusunda dünyada ve ülkemizde okullar kapatılarak sokağa çıkma yasakları uygulanmaktadır. Bu derlemede pandemiyle birlikte değişen yaşam koşullarının, çocuk sağlığı üzerindeki etkilerini değerlendirmek amaçlanmıştır.Araştırmalarda, COVID-19 pandemisinde bağışıklama programında düşüş olduğu, ebeveynlerin sağlık kuruluşlarına gitmeyi ertelediği kaydedilmiştir. Pandemiyle birlikte çocuklarda uyku sorunları, gereğinden az veya aşırı yeme davranışları, fiziksel aktivite yetersizliği, teknolojik cihaz kullanımında artış, artan kaygı durumu ve zaman yönetiminde başarısızlık gibi sorunların geliştiği bildirilmiştir. Bunların yanında çocuğa yönelik ihmal ve istismar tehlikesinin pandemi öncesi döneme göre artış gösterdiği bildirilmiştir.Sağlıklı davranış geliştirmek için çocuk ve ebeveynlerin bilgilendirilmesi ve danışmanlık yapılması gerekmektedir. Toplum kuruluşlarının çocuk sağlığını öne çıkaran programlar geliştirmesi, farklı disiplinlerle işbirliği sağlanarak farkındalık çalışmaları yapılması önerilmektedir.
Il crocifisso ‘accomodato’. Considerazioni a prima lettura di Corte cass., Sezioni Unite civili, n. 24414 del 2021
Authors: Toscano Marcello
Published: November 2021

SOMMARIO: 1. Introduzione - 2. La decisione (in sintesi): una soluzione subottimale - 3. Il ruolo determinante del principio supremo di laicità - 4. Laicità sostanziale, laicità procedurale, accomodamento ragionevole - 5. Discriminazione diretta e indiretta. - 6. Conclusioni.

The crucifix ‘accommodated’. Considerations at first reading of the judgment no. 24414/2021 by the United Sections of the Italian Supreme Court of cassation

ABSTRACT: With decision no. 24414/2021 the United Sections of the Italian Supreme Court of cassation have provided an unprecedented solution to the issue of religious symbols in the classrooms of public schools. In this essay the author analyses the judgment, focusing in particular on three aspects: the relationship between the so-called ‘Italian principle of secularism’ and the reasonable accommodation; the existence or not of discrimination against the teacher who has been obliged to teach under the crucifix; the practical ways in which this ruling can become 'living law' in the Italian legal system.
Dampak Krisis Ekonomi Global Tahun 2008 Terhadap Eksistensi Okun's Law Di Indonesia
Authors: Muanas Arif , Milhani Yuhanida
Published: November 2021

Konsep hubungan negatif antara pertumbuhan ekonomi (Produk Domestik Brutto riil/PDB riil) dan tingkat pengangguran dikenal sebagai hukum Okun (Okunâ€™s law) atau koefisien Okun. Penelitian ini bertujuan untuk menguji dampak krisis ekonomi global tahun 2008 terhadap eksistensi Hukum Okun di Indonesia dengan menggunakan data time series tahun 2000-2014. Penelitian ini dilakukan pada data tahun 2000-2007 (sebelum krisis) dan data tahun 2008-2014 (setelah krisis). Metode yang digunakan adalah analisis Ordinary Least Square (OLS) untuk mendapatkan koefisien regresi atau koefisien Okun. Hukum Okun menyatakan bahwa apabila PDB riil tumbuh sebesar 2,5% diatas trendnya, yang telah dicapai pada tahun tertentu, maka tingkat pengangguran akan turun sebesar 1%. Dari berbagai penelitian yang telah dilakukan oleh beberapa peneliti, diketahui bahwa koefisien Okun di tiap-tiap negara berbeda. Hasil penelitian ini menunjukkan bahwa Hukum Okun berlaku di Indonesia sebelum krisis, dimana koefisien Okun bernilai negatif dan signifikan.Tetapi hukum Okun tidak berlaku setelah krisis, dimana koefisien Okun bernilai negatif dan tidak signifikan.
Acceptance & Commitment Therapy in de behandeling van epilepsie
Authors: Kruitbosch Heleen , Leenders Dorien
Published: November 2021

In deze bijdrage wordt beschreven wat Acceptance & Commitment Therapy inhoudt en wordt een onderzoek naar het effect hiervan in de behandeling van epilepsie beschreven. Daarna wordt een casus beschreven waarin een beeld wordt gegeven van de toepassing van Acceptance & Commitment Therapy in de praktijk. Deze therapie blijkt een waardevolle aanvulling bij de behandeling en begeleiding van mensen met een chronische aandoening, zoals epilepsie.
List of Endemic Flowering Plants from Gudalur Forest Division, Western Ghats, Tamil Nadu
Authors: Prakash L. , Anbarasu C. , Balasubramanian P.
Published: November 2021

The present study was carried out to prepare a comprehensive list of endemic flowering plants found in Gudalur Forest Division, Nilgiri Plateau, Tamil Nadu. A total of 58 species of flowering plants belonging to 43 genera and 27 families were recorded. Majority of the species are Peninsular Indian endemics. Of the 58 endemic species, one belonged to the Critically Endangered, 7 Endangered and 4 Vulnerable category.
SISTEM KENDALI JARAK JAUH ROBOT PEMADAM API DENGAN MENGGUNAKAN SENSOR FLAM DAN SENSOR MQ BERBASIS MOTOR POMPA
Authors: Amin Muhammad , Ananda Ricki
Published: November 2021

Kebakaran adalah suatu keadaan darurat yang disebabkan karena terjadinya kebakaran/ledakan di berbagai tempat yang dapat membahayakan jiwa manusia, harta benda, dan lingkungan. Faktor terjadinya kebakaran karena manusia, berupa pembakaran hutan, membuang puntung rokok sembarangan sampai dengan kurang pengertian atau melanggar aturan. Seperti distasiun tebing tinggi yang hanya menggunakan racun api sebagai antisipasi pemadam kebakaran. Berdasarkan hal tersebut peneliti akan merancang robot pemadam api yang memiliki beberapa input dari modul elektronika seperti pembaca gas, pembaca api, sampai dengan pembaca suhu. Selain itu output  dari robot yang akan dirancang menggunakan motor dc sebagai kipas pemadam api yang difungsikan sebagai pemadam api skala kecil seperti puntung rokok, percikan api yang berasal dari korek api. Motor pompa yang juga digunakan sebagai pemadaman api. Ketika mobil robot mendektesi adanya sumber api atau kebocoran gas, sampai dengan peningkatan suhu, maka robot tersebut akan menyalakan buzzer untuk memberi tahu orang sekitar bahwa adanya potensi bahaya kebakaran. Untuk sistem kendali prototype robot menggunakan modul interface hc-05 yang dihubungkan dengan android.
INFORMATION GAP ACTIVITIES AT THE NINTH GRADE OF SMP NEGERI 7 TANJUNG BALAI
Authors: Maulana Cecep
Published: November 2021

Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis Kesenjangan Informasi Kegiatan pada siswa kelas IX SMP Negeri 7 Tanjung balai. Kegiatan pembelajaran ini mengambil penelitian tindakan kelas. Peneliti dilakukan dalam dua siklus. Setiap Siklus terdiri dari tiga kali pertemuan. Setiap siklus terdiri dari: perencanaan, tindakan, observasi, dan refleksi. Teknik pengumpulan data menggunakan observasi, wawancara dan tes kemudian menganalisis data baik secara kualitatif maupun kuantitatif. Peneliti memberikan pre-test, test cycle 1 dan test cycle 2 khususnya pada teks deskriptif untuk mengukur kemampuan berbicara siswa. Hasil pengujian menunjukkan bahwa (1) penerapan Information Gap Activities dalam pengajaran berbicara sebagai berikut. Langkah pertama dimulai dengan memberikan materi kepada siswa tentang mendeskripsikan suatu hal, yang kedua, siswa berdiskusi dengan kelompoknya untuk membuat percakapan tentang mendeskripsikan sesuatu. Kegiatan Kesenjangan Informasi dilakukan secara berkelompok. (2) Teknik Information Gap Activities dapat meningkatkan kemampuan berbicara siswa. Hal ini dapat dilihat dari hasil pretest dan posttest. Berdasarkan hasil nilai rata-rata pada pretest adalah 55,00. Setelah peneliti mengajar berbicara dengan menggunakan implementasi Information Gap Activities, skor rata-rata siswa menjadi 69,80 pada posttest 1. Kemudian pada posttest 2, skor rata-rata siswa meningkat menjadi 80,05. Teknik Information Gap Activities dapat membantu siswa lebih percaya diri dalam kegiatan berbicara.
LITERASI DIGITAL KEKINIAN AGAR KOMUNIKASI LEBIH BERMAKNA
Authors: Fauziah Rizky
Published: November 2021

Sebagai masyarakat yang tumbuh di era perkembangan teknologi yang begitu pesat, tentu akan saling terhubung satu sama lain. Saat ini tingginya tingkat penggunaan media sosial serta mudahnya dalam mengakses informasi sudah tidak bisa diragukan lagi. Namun masih saja ada masyarakat yang masih termakan oleh berita Hoax. Belum lagi muncul fenomena baru yaitu Fear of Missing Out (FOMO) yang bisa membuat pengguna media sosial merasa gelisah jika ketinggalan dengan yang sedang terjadi di media sosial. Selain itu hal ini juga meyebabkan turunnya kualitas komunikasi yang terjadi karena media sosial maupun fenomena FOMO. Hal inilah yang membuat pentingya literasi digital diberikan agar masyarakat yang tumbuh di era ini bisa semakin cakap dalam menggunakan  media digial terutama media sosial, dan membuat komunikasi lebih bermakna dengan juga menerapkan fenomena Joy of Missing Out (JOMO) yang sudah merasa cukup walau hanya membuka media sosial sebentar. Literasi digital diperlukan agar kegiatan yang menyangkut dengan media digital bisa membawa hal positif untuk penggunannya.
Validasi Metode Analisis Identifikasi Simultan Hidrokuinon dan Asam Retinoat Secara UHPLC-PDA dalam Produk Kosmetika
Authors: Fajri Mohammad Ibnu
Published: November 2021

Penggunaan Hidrokuinon dan Asam Retinoat pada produk kosmetik tanpa resep dokter tidak diizinkan menurut peraturan yang berlaku di Indonesia. Metode analisis yang tersedia saat ini masih menggunakan sistem HPLC yang dijalankan secara individual untuk masing-masing senyawa dan membutuhkan waktu analisis yang lama. Oleh karena itu, diperlukan pengembangan metode yang lebih cepat dan efisien. Pengembangan metode analisis identifikasi simultan Hidrokuinon dan Asam Retinoat dijalankan menggunakan Ultra High Performance Liquid Chromatography (UHPLC) dengan detektor PDA, kolom Hypersil GOLD® C18 (150 mm x 2.1 mm 3µm), fasa gerak metanol - asam format 0,1% dengan sistem gradien, laju alir 0,35 mL/menit dan dideteksi pada 290 nm untuk hidrokuinon dan 354 nm untuk asam retinoat. Parameter validasi yang dilakukan adalah selektivitas dan batas deteksi. Hasil validasi metode menunjukkan waktu retensi untuk hidrokuinon pada 1,93 menit dan untuk asam retinoat pada 11,99 menit. Tidak ada peak yang memberikan waktu retensi yang sama baik pada pelarut maupun larutan sampel. Persamaan kurva kalibrasi untuk hidrokuinon adalah y = 11591x + 1312 (r = 0.999) dan untuk asam retinoat adalah y = 37839x + 17732 (r = 0.999). Nilai batas deteksi dari hidrokuinon dan asam retinoat sebesar 5,92 µg/g dan 7,74 µg/g secara berurutan. Metode ini valid digunakan untuk analisis hidrokuinon dan asam retinoat pada sampel produk kosmetika, serta 67% cepat dan 90% lebih hemat fasa gerak dibandingkan metode yang tersedia saat ini.
System Requirement Specification of Mobile Apps for shrimp farming in Shyamnagar of Bangladesh
Authors: Hasan Roshidul , Prapti Dipika Roy , G M Mostakim , Chakraborty Tapas R
Published: November 2021

Frozen food is one of Bangladeshâ€™s most valuable export items, comprising more than 80% of shrimp. The most cultivated area of shrimp is situated in the southern region of Bangladesh. This research was carried out to identify the core problem in the shrimp farming areas in order to support the related farmers in seeking a solution through the most common technology used by them. The study was conducted in Shyamnagar, Satkhira district with a total of 40 female respondents involved. This research showed that shrimp farming is pressurized by a lack of proper information on disease identification and its management. Mobile apps are considered the most common information providers among that community. The research defined the common problems and necessity through the system requirement specification (SRS) to provide needed details for the farmers that focused on mobile-app development eventually. It was found that disease (82.86%) and water quality (17.14%) are the most common issues while among the diseases White Spot Syndrome Virus and Yellow Head Virus Disease followed by Black Gill disease were the most alarming to handle without pre-management knowledge. The research also suggests developing voice-based mobile apps for shrimp farmers in the local language.