bluuebunny/crossref_metadata_2025 huggingface dataset:
Een mensgericht, gezondheidsgegevens-gedreven ecosysteem
Authors: STEVENS G. , HANSTON L. , VERDONCK P.
Published: November 2021

A human-centered, health data-driven ecosystem

Value-based, connected and integrated healthcare are gaining momentum in the healthcare landscape. Industry 4.0 is transforming healthcare into a data-driven sector. Data and innovation are the foundations of future value-driven healthcare ecosystems. But how will the human aspect remain to play a lasting role? Healthcare continuums are being rolled out as healthcare goes beyond traditional diagnosis and treatment towards prevention and early detection. Health institutions are facing a new generation of ‘health-conscious’ consumers and ‘technology-minded and -adapted’ healthcare professionals. In order to accelerate innovation within healthcare institutions, it must be powered by the personal health-data of an individual, independent of location, life phase and health status. This data will be continuously generated by the daily use of different technologies. Based upon these concepts and shifts, this paper describes a human-centered, health data-driven ecosystem that is built upon the interaction and balance of human actors in every life phase, different environments and societal changes and with different technologies. International and national guidelines and regulations, and ethical norms and values need to be taken into account. Implementation of this health data model will create future value at any time, place and location within this ecosystem. This ecosystem will create value through the realized integrated care by connecting diverse human actors, different environments and various technologies, while still maintaining the empathic relations between the caretaker and the patient/client.
Peningkatan Stock Return Berbasis Capital Structure
Authors: Mutamimah Mutamimah , Baiti Inka Noor
Published: November 2021

Penelitian ini bertujuan untuk menganalisi pengaruh profitabilitas, strktur aktiva, dan Good Corporate Governance terhadap struktur modal dan return saham. Populasi dalam penelitian ini perusahaan Syariah yang tergabung dalam Jakarta Islamic Index (JII) selama periode 2015-2019. Penelitian ini dilakukan dengan metode kuantitatif dengan data sekunder. Teknik pengambilan sampel dengan metode purposive sampling. Sampel yang diambil sebanyak 61 perusahaan. Analisis untuk menguji pengaruh langsung dan tidak langsung dari variabel independent terhadap variabel dependen atau melalui variabel interveningnya. Metode analisis yang digunakan adalah regresi data panel dengan menggunakan program Eviews. Hasil penelitian secara umum dapat disimpulkan bahwa profitabilitas memiliki pengaruh negatif dan signifikan terhadap struktur modal, struktur aktiva mempunyai pengaruh positif dan signifikan terhadap struktur modal, good corporate governance tidak mempunyai pengaruh terhadap struktur modal, dan profitabilitas berpengaruh positif dan signifikan terhadap return saham dan struktur modal tidak mampu memediasi pengaruh profitabilitas dan struktur aktiva dan GCG terhadap return saham.
TRENDS IN HIGHER EDUCATION IN THE ASIA-PACIFIC REGION
Authors:   Almaty Management University (AlmaU), Ibzharova Sh. , Koyanbayeva G. ,   Institute of Philosophy, Political Sciences and Religious Studies CS MES RK
Published: November 2021

The article focuses on the trends of higher education in the countries of the Asia-Pacific region. The authors focused on the aspects of changing the landscape of global education in the direction of the Asia-Pacific region (APR), and also through the prism of cultural foundations presented models of education of the East and West. The uniqueness of the article lies in the analysis of the development of higher education in the Asia- Pacific region based on a review of national and state programs for the development of higher education in the Asia-Pacific countries, reports and strategies of international organizations, and a secondary analysis of the research results of international research funds, centers, projects and individual experts.
THE FUNDAMENTAL HUMAN RIGHT TO HEALTH, THE SIGNIFICANCE OF NON-COMMERCIALIZED HEALTH CARE SYSTEM, AND THE CHALLENGES OF NEOLIBERAL CAPITALISM
Authors:   PhD,  senior  Lecturer,  chief  researcher,  Suleyman  Demirel University, Almaty, Kazakhstan, Zhussipbek G. , Nagayeva Zh. ,   MA,  researcher,  Suleyman  Demirel  University,  Almaty, KazakhstanЖусипбек Г., Нагаева Ж.
Published: November 2021

This article explores the fundamental human right to health and the significance of the non-commercialized healthcare system through the prism of the universality of human rights. Also, it critically analyzes neoliberal capitalism, which principles and ideas laid the grounds to undertake the structural reforms in the health care systems in many countries worldwide, including Kazakhstan. Under-financing of health care and the commercialization and commodification of the health care sector became global problems negatively affecting life millions of people and became especially urgent after the COVID-19 Pandemic. The article briefly analyzes the sociallyoriented model that exists in Scandinavian countries, where the problems of commercialization and commodification of the health care system and the optimization and curtailment of social programs have been largely avoided.
THE ECONOMIC AND FINANCIAL SOURCES OF THE ISIS TERRORIST ORGANIZATION
Authors:   Khoja   Akhmet   Yassawi   International  Kazakh-Turkish  University,  Turkestan, Kazakhstan.    ORCID    ID:    0000-0002-8164-8049,    bauyrzhan.botakarayev@ayu.edu.k, Botakarayev B. , Tolegenov M. ,   Khoja   Akhmet   Yassawi   International  Kazakh-Turkish  University,  Turkestan, Kazakhstan. mukhit.tolegenov@ayu.edu.kz, Benli Y. ,   Prof. Dr. Erciyes University, Kayseri, Turkey, ybenli@erciyes.edu.tr
Published: November 2021

While in the past, discussions about war and peace were constantly born in various spheres of society, such as philosophy, humanities, and journalism, today these topics have become one of the most important issues of political science. However, the specific positions and opinions of leading religious experts on this issue were not particularly noted, as they did not contradict the secular point of view. In the era of globalization, the network of interaction between people and society has become a complex phenomenon. Globalization not only contributes to life in a positive way, but also has a negative impact. Although scientific development, which contributes to positive changes in the world, has entered an effective and rapid process in recent years, the sphere of influence of terrorist organizations is also spreading beyond the borders of the country. Terrorist organizations, on the other hand, use this process to their advantage and threaten the whole world. A terrorist organization called ISIS was able to expand its sphere of influence in a short time, taking advantage of the benefits of globalization. Although it initially became a specific regional threat, over time it became a threat to the world. For this reason, with the fear that it will negatively affect the world and its future, we have set out to determine the structure, purpose, economic and financial foundations of this organization and the main mechanisms for combating them.
THE PROBLEM OF IGNORANCE IN THE PHILOSOPHY OF AL-FARABI
Authors:   al-Farabi Kazakh National University, Almaty, Kazakhstan, Rushanova N. , Syrgakbayeva A. ,   Al-Farabi Kazakh National University, Kazakhstan
Published: November 2021

Al-Farabi devoted a significant part of his work to the development of social and ethical issues. The article attempts to reveal the content of the concept of “ignorance” in the heritage of al-Farabi. The need to raise this question is due to the fact that Farabi’s philosophy is permeated with the understanding of the collisions of knowledge and ignorance, right and wrong in the attitude of people to each other and to the world around them. It can be argued without exaggeration that the concept of ignorance, in its various aspects, occupies a central place in the work of the Arab thinker and sets the scale and specifics of his social project. Ignorance in the interpretation of al-Farabi is primarily the opposite of virtue, that is not only knowledge, education, but also a wrong view of life, of its values and goals. This wrong view gives rise to wrong actions, distorted morality, and with it - social relations that do not correspond to the concept of truly human.
KAZNET: ANALYSIS OF ART COMMUNITIES
Authors:   Institute of Philosophy, Political Science and Religious Studies CS MES RK, Shaidulina D.
Published: November 2021

The article is devoted to the study of Kazakhstani independent art platforms on the Internet. As the objects of research, the author selected two leading artistic resources of the Kaznet, dedicated to domestic contemporary art - Astral Nomads and Qazart, the analysis of which made it possible to reveal the significance of digital technologies and the virtual world for the modern culture of Kazakhstan. The platforms emerged as a response to problems of material destruction threaten art objects and aspiration for promotion of Kazakhstani contemporary art. In current conditions, we are able to trace the tendency of increasing involvement into virtuality.
Generation Time and Independence
Authors:   L.N.Gumilyev Eurasian National University, Kazakhstan, Tumashbay T.
Published: November 2021

This article discusses the value changes in the time of generations over the years of Kazakhstan’s independence. It was considered that in the first years of independence, Kazakh society, as a result of the creation of a value vacuum in people’s behaviour, was disoriented in the spiritual and material spheres. The issue of spiritual obscenity was also addressed. At the same time, the influence of an atheistic society on a person’s worldview, the factor of polyreligiosity of one nation, the inability of the Kazakh people to occupy the cultural space as a state of the forming nation, living with one-day interests, was recorded. It was shown that the time of generations is associated with the political freedom of citizens and that this freedom is a guarantee of the security of the state. The article presents the views of philosophers such Hegel, Marx, Foucault, Zh.Abdildin, G.Yessim, B.Kolbayev, Sinan Uzbek, Sh.Aitmatov. In the novel of Sh. Aitmatov “Cassandra’s Brand” in the study of universal values were given thoughts such as evil in non-religious society, struggle against it, conscience, and shame.
National Identity of Ukrainians in the Context of National Security
Authors:   Center for Army, Conversion and Disarmament Studies, Poita Y.
Published: November 2021

The peculiarities of the national identity of Ukrainians significantly influenced the process of national and state-building in Ukraine, thereby determining the national identity and subsequently the political behavior of its citizens. One of the striking examples of the influence of national identity in Ukraine is the events of 2013-2014 in Crimea and in the Donetsk and Luhansk regions, when, under the influence of the internal political crisis and external influence, part of Ukrainian society took part in rallies, incl. with the aim of changing the social system and even secession from the country, which led to threats to the territorial integrity of Ukraine. The purpose of this article is to identify the features of the national identity of Ukrainians, which created the basis for massive anti-Ukrainian actions in 2013-2014, as well as modern trends in the development of Ukrainian society, and their impact on the national security of the state. The main results and conclusions of the article: significant regional differences in the identities of Ukrainians formed the conditions for the emergence and external construction of the socio-political crisis. Strong regional identity, low support for Independence, linguistic and political preferences of the inhabitants of the East and South of Ukraine became the key factors that influenced the stability of the state. Changes in Ukraine's policy after 2014, in the context of a military conflict with Russia, changed the characteristics of national identity, and probably contributed to the formation of a stronger Ukrainian state. The article can be used to further study the problematic aspects of the formation of national identity in the post-Soviet space, as well as to simulate scenarios for the development of political crises in order to develop an effective state policy that will help strengthen national unity, meet the needs of society, and find compromises between different social groups.
Comportamiento de los millennials frente al servicio de delivery del sector de restaurantes en tiempos de pandemia
Authors:   Universidad Técnica de Machala. Ecuador, SORNOZA Monica A. , SOTO Dany F. ,   Universidad Técnica de Machala. Ecuador, SOTO Ana E. ,   Universidad Técnica de Machala. Ecuador
Published: November 2021

tiempos de pandemia. El estudio se desarrolla en la provincia de El Oro, Ecuador; es de carácter descriptivo con metodología cuantitativa, por ello se ejecuta haciendo uso de los métodos de revisión documental y aplicación de encuestas online a una muestra de 384 millennials orenses con edades comprendidas entre los 21 y 41 años. Los principales resultados muestran que, por necesidad y por adaptación, se incrementó demanda del servicio de delivery y que el consumidor millennial prioriza la utilidad del servicio antes que la notoriedad de la marca.
COMPARISON OF TWO STAINING METHODS FOR ANODIZING IN ALLOY 6063 ALUMINUM PROFILES
Authors:   Universidade de Caxias do Sul, Engenharia Química, PESSUTTO Ana Carla , JONKO Eliena
Published: November 2021

Aluminum stands out for being a light, corrosion-resistant, and recyclable metal, achieving wide coverage in the market. When incorporated into alloying elements, it is possible to acquire other desirable characteristics. Alloy 6063, intended for architectural purposes, has aesthetic, structural, and strength functions. This study aims to compare two different staining methods on the surface of anodized profiles of aluminum alloy 6063. Anodized finishing is performed through an electrolytic process using sulfuric acid as an electrolyte to change the surface layer of the material, ensuring a more resistant aluminum oxide film than that formed naturally. For decorative purposes, the anodic film coloration can be performed by several methodologies, including, in this case, the coloration by organic adsorption, with the use of aniline, and the electrolytic coloration, composed of tin sulfate salts, both for obtaining the black color. To compare, neutral saline mist tests, scanning electron microscopy analysis, determination of the anodic layer thickness, and immersion tests with 3.5 percent sodium chloride for 1000 hours. The results obtained highlight that both were shown to be resistant to corrosion due to the fact that they do not present corrosion points when exposed to the neutral saline mist test for 600 hours. In the immersion tests, both remained resistant to sodium chloride. Because both methodologies present satisfactory results in all tests, the quality of the applied stains is ensured, and it is found that they are equivalent when the parameters discussed are used.
PENGARUH KESELAMATAN KERJA FISIK DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN
Authors: Setiawan Iwan , Khurosani Aan
Published: November 2021

Today's steel industry is very competitive competition. Therefore, each company is required to improve the quality and make the right business strategy to improve company performance. This study aims to clarify the effect of occupational safety and the working environment of the job performance and job satisfaction as an intervening variable in PT. Krakatau Posco. Cilegon Banten. The study was conducted by taking samples using non-probability sampling technique, which is a technique that does not provide opportunities or equal opportunity for each element or member of the population to be selected into the sample. While the technique of taking informants using purposive sampling technique is a technique for determining sample with some specific considerations that aim that the data obtained will be more representative. Collecting respondent data obtained from 90 employees of PT. Krakatau Posco Cilegon, with a questionnaire consisting of questions and statements. Respondents' answers to questions and statements were analyzed qualitatively and quantitatively, and the answers were analyzed with methods of data analysis techniques Partial Least Square using version SmartPLS 2.0.m3. The analysis showed that the effect of occupational safety on job satisfaction is positive and significant. Furthermore, that the effect on job satisfaction working environment that is positive and significant. Occupational safety and influence on the performance of the work that is positive and significant. And the influence of the working environment on the performance of the work as well as a positive and significant effect of job satisfaction on job performance positively and significantly.
PENGARUH PELATIHAN FORMAL DAN KOMPENSASI TERHADAP KINERJA GURU DENGAN MOTIVASI INTRINSIK SEBAGAI VARIABEL INTERVENING (Studi Kasus pada Yayasan Pendidikan Informatika Serang)
Authors: Adiwinata Djaka , Triadji Bambang , Kuswantoro M
Published: November 2021

Teacher role in challenges organization and reaching its objectives can happen when education teacher speaks apply what has gathered in training to students, the compensation, and motivation to excel. This study aims to see if formal training and compensation to depend on the intrinsic motivation and performance teacher at Yayasan Pendidikan Informatika. In this research, the methodology used is research causality. To answer the hypothesis using data analysis Structural Equation Model (SEM) using PLS (Partial Least Square). Based on the results of testing SEM obtained formal training have had a positive impact and significant impact on motivation intrinsic teachers, compensation influential positive and significantly to motivation intrinsic teachers, formal training has a positive and significant impact on teacher performance, compensation it has some positive effects and significantly correlates with is placed on teacher performance, Intrinsic motivation has a positive and significant effect on teacher performance.
Determinación de la presencia de residuos antibióticos betalactámicos en los productos lácteos expendidos en la ciudad de Cajamarca
Authors: Gutiérrez Felipe , Rojas-Vásquez Zulema , Quispe-Rodríguez Brando , Quito-Vásquez Fanny , Llasac-Rojas Milagros , Terán-Piña Julio , Gutiérrez-Arce Walter
Published: November 2021

El trabajo tuvo como objetivo determinar la presencia de residuos antibióticos betalactámicos en el queso mantecoso expendidos en Cajamarca, 2019. Para ello, durante el mes de agosto, se tomó una muestra semanal en cada uno de los seis puntos de expendios seleccionados. Se eligió a aquellas tiendas que vendían más de 30 kg de queso mantecoso por día. También se compararon los resultados de los análisis con los Límites Máximos del Residuo (LMR) de los antibióticos del grupo de los betalactámicos, considerados por los Codex Alimentarius (para amoxicilina, ampicilina, y penicilina) y por el Reglamento de la Unión Europea (para cefalexina), para determinar la calidad del producto. Se obtuvo que el antibiótico con mayor presencia fue la penicilina; incluso, en uno de los puntos de muestreo, rebasa hasta en casi un 300% (11.13 µg/kg), el LMR permitido por el Codex Alimentarius (4 µg/kg). Y otro punto de muestreo, también mostró cantidades de residuos de penicilina en sus productos (3.52 µg/kg) muy cercanos a los permitidos. Concluyendo que, aproximadamente, 1 de cada 6 puntos de ventas de queso mantecoso sobrepasa el LMR de penicilina, producto de uso veterinario y de efecto residual prolongado, que incluso, como ya estamos demostrando, permanece en los productos de transformación, como el queso.
Factores de riesgo y perfil epidemiológico de la cisticercosis porcina/teniasis humana en el distrito de Zapatero
Authors: Sánchez-Cárdenas Hugo , Puicón Víctor , Arévalo Ramírez Heriberto
Published: November 2021

El presente estudio tuvo como objetivo evaluar los factores de riesgo y el perfil epidemiológico de la cisticercosis porcina/teniasis humana en el Centro Poblado Menor de Bagazán. Se trabajó con una muestra de 100 personas encuestadas, 179 muestras coprológicas humanas y un análisis cualitativo y cuantitativo de 176 cerdos. Los resultados demostraron que el 61% de los pobladores encuestados mencionaron que los factores sociopolíticos son buenos y el 39% manifestaron que es regular, en cuanto a los factores económicos el 100% de los pobladores manifiestan que las condiciones económicas son malas. El 64% de los criadores de cerdos mencionan que crían los cerdos sueltos encerrados en un corral, el 24% crían sueltos sin control, el 6% lo sueltan por horas y el 4% crían a los cerdos amarrados. Para el sistema de faenamiento el 93% de los encuestados manifiestan que es regular, el 5% consideran que es bueno y el 2% que es malo, encontrándose diferencias significativas con p = 0,00. De los 42 cerdos sacrificados 3 cerdos estaban infestados con cisticercos en el músculo del lomo la cara, pero era una infestación leve. El 100% de las personas en las que se realizó análisis coparasitológico mediante la técnica cuantitativa de Mc Master modificado y técnica cualitativa de flotación en el laboratorio para detectar teniasis en humanos dieron como resultado negativo.
Presupuesto, gasto social y desarrollo municipal
Authors: Romano Luis E.
Published: November 2021

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 53, No. 594, 1998: 392-396.
Reacomodos en la derecha y la izquierda salvadoreñas
Authors: Editor El
Published: November 2021

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 53, No. 595-596, 1998: 419-432.
El desarrollo económico comunitario. Diagnóstico socioeconómico de cien comunidades
Authors: Montoya Aquiles
Published: November 2021

En este artículo, el autor presenta un estudio sobre el nivel de desarrollo de 100 comunidades -ubicadas en 10 departamentos del país- conformadas por repatriados, repobladores y combatientes desmovilizados, a quienes se les considera parte de una nueva estrategia denominada Desarrollo Económico Comunitario. Estas comunidades buscan, de manera colectiva y organizada, desarrollar las actividades económicas para resolver sus problemas de pobreza y marginación. Aunque los resultados no son por completo satisfactorios, el autor considera que "la mayor riqueza del esfuerzo comunitario no está en lo logrado sino en sus posibilidades".

ECA Estudios Centroamericanos, Vol. 53, No. 595-596, 1998: 473-496.
SISTEMA DE MEDICIÓN DE LA CALIDAD DE LA EDUCACIÓN: ¿FINES
PEDAGÓGICOS O RENDICIÓN DE CUENTAS?
Authors: Puentes Muñoz Bernardita , García Hernández María Luisa , Porto Currás Mónica
Published: November 2021

En Chile se ha instalado una cultura de la evaluación orientada fundamentalmente a la rendición de cuentas, que utiliza la prueba estandarizada SIMCE como mecanismo para medir los resultados de aprendizaje de los y las estudiantes y -con ello- la calidad del sistema. Sin embargo, a partir de la identificación de algunos efectos no deseados de la aplicación de esta prueba, la Agencia de Calidad de la Educación ha reorientado el uso de sus resultados desde un énfasis en el accountability a un foco centrado en la retroalimentación de la práctica pedagógica, con el fin de mejorar la calidad de la enseñanza. Enmarcado en este contexto, este estudio tuvo por objetivo general conocer la percepción del profesorado sobre el uso de los resultados de la prueba SIMCE en un centro de educación pública de Santiago de Chile, con el fin de averiguar si son utilizados desde esta nueva resignificación pedagógica. Para ello, se eligió un enfoque empírico-analítico, con un estudio descriptivo, utilizando un cuestionario elaborado ad hoc. Los datos muestran que coexiste un uso pedagógico de estos datos de aprendizaje en conjunto con aquellas acciones que deberían evitarse, por lo que el foco pedagógico no ha logrado desplazar la atención excesiva en la rendición de cuentas.
3D deep geothermal reservoir imaging with wireline distributed acoustic sensing in two boreholes
Authors: Martuganova Evgeniia , Krawczyk Charlotte M.
Published: November 2021

Abstract. Geothermal exploration will help moving towards a low-carbon economy and provide a basis for green and sustainable growth. The development of new practical, reliable methods for geophysical characterisation of a reservoir has the potential to facilitate a broader application of deep geothermal energy. At the Groß Schönebeck in-situ laboratory, a unique vertical seismic profiling (VSP) dataset was recorded in two 4.3 km deep geothermal boreholes using fibre optic cables in early 2017. The experiment set-up consisted of 61 vibrator points organised in a spiral pattern around the well site to ensure a proper azimuth distribution in the target reservoir section. Data were processed using a standard workflow for VSP. As a result, a detailed 3-dimensional 0.75 × 1 × 4.5 km size image around the existing boreholes was created using the Kirchhoff migration algorithm with restricted aperture. The imaging resolved small-scale features in the reservoir essential for the future exploration of the geothermal research site. Borehole data with vertical resolution up to 16 m revealed the existing depth variations of the Elbe basis sandstone horizon at 4.08–4.10 km depth and indications of an unconformity in the area where we expect volcanic rocks. In addition, in the borehole data a complex interlaying with numerous pinch outs in the Upper Rotliegend reservoir section (3.8 to 4 km depth) was discovered. Thereby, we demonstrate that wireline fibre optic data can significantly contribute to exploration by providing an efficient and reliable method for deep geothermal reservoir imaging.
Regime transitions of Australian climate and climate extremes
Authors: Frederiksen Jorgen Segerlund , Osbrough Stacey Lee
Published: November 2021

Abstract. Systematic changes, since the beginning of the 20th century, in average and extreme Australian rainfall and temperatures indicate that Southern Australian climate has undergone regime transitions into a drier and warmer state. South-west Western Australia (SWWA) experienced the most dramatic drying trend with average streamflow into Perth dams, in the last decade, just 20 % of that before the 1960s and extreme, decile 10, rainfall reduced to near zero. In south-eastern Australia (SEA) systematic decreases in average and extreme cool season rainfall became evident in the late 1990s with a halving of the area experiencing average decile 10 rainfall in the early 21st century compared with that for the 20th century. The shift in annual surface temperatures over SWWA and SEA, and indeed for Australia as a whole, has occurred primarily over the last 20 years with the percentage area experiencing extreme maximum temperatures in decile 10 increasing to an average of more than 45 % since the start of the 21st century compared with less than 3 % for the 20th century mean. Average maximum temperatures have also increased by circa 1 °C for SWWA and SEA over the last 20 years. The climate changes are associated with atmospheric circulation shifts and are indicative of second order regime transitions, apart from extreme temperatures for which the dramatic increases are suggestive of first order transitions.
Incidence And Risk Factors Of Maternal And Fetal Outcomes Among Patients Of Placenta Previa With And Without Placenta Accreta
Authors: Khattak Samina Naseem , Akram Umbreen , Pervaiz Erum , Anayat Maria , Munir Tahir Ahmad , Akhter Naheed , Jan Athar Ahmad
Published: November 2021

Objective: The aim of the study was to evaluate maternal and fetal outcomes among patients of placenta previa (PP) with and without placenta accreta (PA). Methodology: All patients who underwent cesarean section for PP and PA were analyzed retrospectively at a tertiary care Combined Military Hospital Kharian, Pakistan, from February 2015 to March 2018. Maternal and neonatal data were obtained from medical records and the hospital database system. Results: PA was found in 37 patients from 111 patients of PP and 74 were without PA with the rate of approximately 2/1000 and 4/1000 respectively were included in the study. The mean age was 31.16±2.65 (range 22–37) years, mean gravidity of 3.69 ±1.40 (range 1 - 9), mean parity 2.57±1.01 (range 1–5), mean number of cesarean sections 2.10±0.66, (range 1-3) and a mean gestational age at the time of cesarean section was 35.65±2.46 (range 28–41) weeks. The maternal risk factors revealed marked differences between placenta previa with accreta and without accrete. The mean intraoperative blood loss in PA was 3,000ml, with a loss of 2,000ml occurring in 60%, and 3,000 ml in 21% of the PA cases. The mean pRBC transfusion was 4 units, while 17% received 6 units. Fetal growth restriction was not seen. A total of 12 neonates were admitted in NICU, with 03 neonatal deaths. There was no maternal death. Neonates born to women with placenta accreta had significantly lower birth weight, Apgar scores at 1 min and 12% required admission to NICU with 3 neonatal deaths. Conclusion: The advanced maternal age, past cesarean or uterine surgery, high parity as well as multiple gravidity were the risk factors for adverse fetal and maternal outcomes.
Pharmacological Treatment Of Osteoarthritis In A Nutshell
Authors: Munir Mehtab , Memon Khalid Mustafa , Jaffri M Sajid Abbas
Published: November 2021

Osteoarthritis, an inflammatory, degenerative disease of joints mostly affects weight bearing joints in old age. Treatment modalities are categorized into non-pharmacological, pharmacological and surgical. Among pharmacological options, oral formulations are mostly used. Acetaminophen is considered as first line though, NSAIDs are well established choice for the management of osteoarthritis and mostly employed for the same. However NSAIDs are associated with gastric adverse effects. Symptomatic slow acting osteoarthritis drugs like glucosamine, chondroitin sulfate, diacerein and avocado soybean saponifiables are considered as maintenance therapy as they have shown to reserve joint space width. Topical formulations are good for patients with co-morbidities. For patient not responding to other modalities, opioids and duloxetine are employed but with caution. Intra-articular injections like corticosteroids, hyaluronic acid and Platelet rich plasma are ranked highest in efficacy. Newer agents like Nerve growth factor- inhibitors, Interleukin-1 antagonists and certain neutraceutical preparations are under investigation for osteoarthritis management
Evaluation Of Weight Changes On Wistar Rats Induced By Erythromycin And Aqueous Neem Leaves ExtractEvaluation Of Weight Changes On Wistar Rats Induced By Erythromycin And Aqueous Neem Leaves Extract
Authors: Adnan Nausheen , Bukhari Uzma , Raza Iffat
Published: November 2021

Objective: To evaluate weight changes on the liver of male (albino wistar) rats induced by erythromycin. To assess the outcome of aqueous Neem leaf extract on erythromycin induced hepatic injuries. Methodology: Eighty male albino wistar rats were taken randomly and were divided into 4 groups of 20 animals each. Group A as a control group. Group B rats were treated with erythromycin drug. Group C rats were treated with erythromycin along with Aqueous Neem leaves extract. Group D were given only Aqueous Neem leaves extract. Body weight of animals was recorded initially and also after experimentation. After 14 days animals were sacrificed, liver weight was also recorded. Results: The liver of erythromycin treated animals group B were little bigger in size and more reddish. However erythromycin plus Neem treated animals of group C livers were almost like liver of control group A and only Neem given group D animals, liver were exactly same appearance like control group A.Rise in absolute and relative weight of liver was because of drug toxicity. Conclusion: Its established from this recent study that Aqueous Neem leaves extract being a powerful antioxidant, decreased oxidative stress and hepatic injury caused by erythromycin.
Outcome Of Immediate PPIUCD At Follow Up Visit In Women At A Tertiary Care Hospital In Karachi, Pakistan
Authors: Suboohi Sadia , Abbasi Sughra , Pario Saba
Published: November 2021

Objective: To evaluate the outcome of Immediate Post Partum Intrauterine Contraceptive device (PPIUCD) insertion among married women of reproductive age at a tertiary care Creek General Hospital, Karachi, Pakistan. Study Design: Prospective Interventional study. Methodology: The clinical study was conducted in department of Obstetrics & Gynaecology, Creek General hospital Karachi from August 2015 to July 2016. One hundred and twenty five women were selected for immediate PPIUCD insertion, however the result was analysed for hundred women as twenty five were lost to follow-up. PPIUCD was inserted within 10 minutes of delivery of placenta. Follow up was done at 6 weeks, the primary outcome measures were the clinical outcomes in terms of safety (irregular vaginal bleeding, abnormal vaginal discharge, infection and perforation) and efficacy (un-descended IUCD strings, expulsion, discontinuation and pregnancy). The results were analyzed by SPSS data analysis software (IOBM). Results: Among hundred women in whom PPIUCD was inserted and returned for follow-up, majority (44%) were in age group 26-30 years; around 52% had primary or less education, and considerably high (84%) belonged to the low socio economic status. Moreover, majority (46 %) had 3 or more alive children. Importantly, 73% women had IUCD inserted after vaginal delivery. As safety was evaluated, irregular vaginal bleeding was observed in 15%, abnormal vaginal discharge (20%), infection (11%), abdominal pain (4%) and perforation in only 1% of cases. Finally, in terms of efficacy the undescended IUCD strings were observed in 7%, expulsion incidence (6%), discontinuation requested by (5%) and none of the case ended up in pregnancy. Conclusion: Post partum IUCD insertion immediately following delivery is an effective, safe, and acceptable long-term reversible method available for postpartum contraception.
Perception Regarding Oral Health Among Patients Visiting Dental Outpatient Department
Authors: Asim Saima , Naqvi Syed Muhammad Zulfiqar Hyder , Jafry Syed Imtiaz Ahmed , Naz Shikoh
Published: November 2021

Objective: To assess knowledge, attitude and practice regarding oral health among patients visiting dental OPD in hospitals of district Malir, Karachi. Study Design and Setting: A cross-sectional study was conducted at dental outpatient departments of two hospitals of district Malir, Karachi. Methodology: A total of 393 participants were randomly interviewed by the principal investigator with the help of structured questionnaire developed specifically for the study after obtaining written informed consent over the study of 6 months. Data was entered and analyzed in SPSS version 21. Inferential analysis was performed using chi-square test whereas binary logistic regression was used to develop a risk assessment model for the study outcome. The significance level was set at 0.05. Results: Overall 31.8% of the study participants had adequate knowledge, 25.2% had adequate attitude whereas 32.2% had adequate practices with regards to oral health. Furthermore, multivariable analysis revealed that higher qualification of the study participants had significant positive associations with adequateness of all of the knowledge, attitude and practices of the study participants regarding oral health at p-value of <0.05. Conclusion: The level of knowledge and appropriateness of attitude and practices of the study participants was less than satisfactory. The higher education level had a positive impact over the oral health of the participants. It is recommended that healthcare providers and government, in their respective capacities, educate and persuade people to take better care of their oral health.
Huge Thyroglossal Duct Cyst Mimicking As Goiter In An Adult Man
Authors: Udaipurwala Iqbal Hussain , Sadiq Sana Muhammad , Aslam Sohail
Published: November 2021

Thyroglossal duct cyst is the most common congenital cervical mass found mainly in children but only 7% of them are among adult population. They are mostly asymptomatic and found around the region of hyoid bone. Their size usually varies around 1.5 to 3cms. but cases are reported with unusually larger sized cysts, which may cause pressure symptoms over upper aero-digestive tract. We are reporting a case of unusually huge thyroglossal cyst of size of 6 x 8 cms in a 26- year-old man. This cyst was not apparent at time of birth or in early childhood but appeared later on. Initially it was very small but progressively and gradually increased to its present size. On first look, it appeared as thyroid swelling with soft to firm in consistency but on examination it was moving with both deglutition and tongue protrusion. Ultrasonography and CT scan of the neck confirmed the diagnosis of thyroglossal cyst. Thyroid scan showed, thyroid gland in its normal position. Sistrunk’s operation was done with a midline vertical incision and the subsequent recovery was uneventful
FUNDAMENTALS AND SOCIO-ECONOMIC RESULTS OF THE PLACEMENT AND DEVELOPMENT OF AGRICULTURE IN THE SOUTHERN REGION
Authors:   South Kazakhstan University named after M.Auezov, Shymkent city, Republic of Kazakhstan, Yessimov E.K. , Sultanbekova P.S. ,   South Kazakhstan University named after M.Auezov, Shymkent city, Republic of Kazakhstan, Shayanbekova B.R. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan, Omarov K.A. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan, Bulanbayeva P.U. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan
Published: November 2021

There are two main reasons for the development of cotton growing in the southern regions of the country: the first is objective, the second is subjective. An objective reason for the development of cotton growing in the southern regions of the country is the natural climate and relief of the region. The southwestern, southern part of the region is located on the plains of the Turan depression. In particular, the climate of the region has its own characteristics: dry air, predominance of sunlight and hot days, long autumn, sufficient and convenient location of water sources for irrigation. The climate of the Turkestan region is similar to that of neighboring Uzbekistan in terms of sunshine and hot days from May to October, and even higher than in a number of other agricultural countries. The article states in detail that the only way to solve the problem of economic independence under favorable climatic conditions is the need for efficient use of agricultural land resources. It also describes the structure of agricultural land in the southern part of the country, the relevance and development of crop production through the introduction of scientific and technological progress, the basis for the effective use of land resources and socio-economic results. In general, in the context of the development of world market relations, the effectiveness of the reforms carried out in our country will undoubtedly allow our country to develop economically.
DEVELOPMENT OF THE INNOVATIVE POTENTIAL OF UNIVERSITY TEACHERS IN ADDITIONAL PROFESSIONAL EDUCATION
Authors:   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan, Yakubova D.E. , Saparkyzy Zh. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan
Published: November 2021

The article considers the theoretical foundations of the creation and understanding of the effectiveness of the development of innovative potential of teachers of universities with a personal point of view. The result of the innovation process in education is the application of innovations in theory and practice. Innovation in the education system is the introduction of innovations for the purpose of education, the transformation of new approaches and practices and forms of education, the introduction and dissemination of new pedagogical systems, the creation, development and implementation of new school management technologies. to meet the new requirements. The concept of an innovative educational process as a system of primary values characterizes it as spiritual production, and its product is not only the acquisition of new knowledge and values, but also the disclosure of the true strengths and abilities of students. Innovations in education are based on socially significant values: people, life, work, home land. This is considered as an indispensable condition for creating an effective model for the development of innovation potential of teachers of universities at the expense of using innovations in additional professional education. The basic concept of "innovative potential of university teachers" is defined. The purpose of this article is to consider the theoretical aspects of the development of innovative potential of teachers in the system of additional professional education.
CLUSTERS AS A SUBJECT OF MODERN ECONOMY
Authors:   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan, Smagulova Zh.B. , Mukhanova A.E. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan
Published: November 2021

The article is devoted to the analysis of clusters as a new factor of increasing competitiveness in the modern economy. The initial preconditions for the formation of clusters are described (the presence of competitive enterprises, presence of competitive advantages for cluster development in region, geographical concentration, an extensive selection of participants, existence of links and interactions between cluster entities). The characteristic features of clusters are given (the possibility of research and development; qualification of the workforce; improvement of labor potential, collective vision and leadership; proximity of suppliers and connections with them; availability of capital; access to specialized services; associated structures; intensity of network formation; entrepreneurial energy; innovation and training). The general features of cluster formations are characterized (presence of critical mass; specialization of firms on various aspects of the value chain; mainly horizontal structure of relations and regulation) The classification of clusters is given (by territorial coverage, by stage of cluster development, by degree of products novelty, by role in the system of exchange and use of knowledge, by presence and degree of development of elements in cluster structure, by level of aggregation of cluster participants, by nature of the industry of enterprises participating in the cluster). The models of cluster formation (Italian, Japanese, Finnish, North American, Indian-Chinese, etc.) are highlighted.
Dementia: need for studies in the new era
Authors: Nathaniel Eemaz , James Aimen
Published: November 2021

Current insights into the structure and function of the human brain has brought about revolutionary changes in concepts about normal and abnormal conditions affecting it. An age-old issue is that of Dementia, previously ignored as an inevitable consequence of aging or mental disorder, that can now be studied in greater depth and perhaps manged more efficiently in light of new research.
The Question of Drawing a Design Scheme of a Wagon with a Non-Symmetrically Located Freight
Authors:   Department of Highway Engineering, Academy of Logistics and Transport, Almaty 050012, Kazakhstan, Solonenko Vladimir , Musayev Janat ,   Department of Highway Engineering, Academy of Logistics and Transport, Almaty 050012, Kazakhstan, Zhauyt Algazy ,   Department of Electronics and Robotics, Almaty University of Power Engineering and Telecommunications named after G. Daukeyev, Almaty 050013, Kazakhstan, Kuparov Valikhan ,   Department of Electronics and Robotics, Almaty University of Power Engineering and Telecommunications named after G. Daukeyev, Almaty 050013, Kazakhstan
Published: November 2021

Violations of the stability of a wagon with an asymmetrically positioned freight can lead to a threat to the safety of train traffic, the safety of freight on the route and transport facilities. The design diagram of a wagon with an asymmetrically located freight drawn up in the article and the equations obtained in an analytical way, oscillations of the sprung mass of a wagon with an asymmetric arrangement of the freight, characterizing the longitudinal and transverse displacement of the center of mass of the freight, can be used for mathematical modeling of forced vibrations and impact on the track of a wagon with asymmetrically located freight in various operating conditions.
Impacts of Covid-19 on Migration Dynamics and Remittances in Sub-Saharan Africa (SSA)
Authors: L.E.O. Abejide , S. Alaba
Published: November 2021

The paper therefore x-rays the impacts of the COVID-19 pandemic on migration dynamics by analyzing types and trends dynamics of migrants’ movement, demographic dynamics of migration as related to the inflow of remittances (both cash and in-kind) to SSA countries prior to the pandemic. Also discusses the constraints of transferring cash remittances and subsequent decline posed by the COVID-19 outbreak during and beyond the pandemics. Secondary evidence from Somali and Nigeria were analyzed on the constraints of remitting cash, while in-kind remittance from the Republic of Chad was evaluated. The importance of remittances to the home communities was established. Measures to safeguard SSA migrants’ mobility and their remittances, citing some selected countries of destination, were exploited. The paper concludes that COVID-19 impacts on migration should be opportunities for policymakers (both home and destination countries) to reset their efforts towards protecting migrants and their future activities.
Prospects for studying the pharmacokinetics, pharmacodynamics and pharmacogenetics of vitamin C in patients with neurological diseases and mental disorders
Authors: Goncharova P. S. , Davydova T. K. , Zhukova N. G.
Published: November 2021

Ascorbic acid (vitamin C) is a vital nutrient that belongs to the group of antioxidants. Vitamin C plays an important role in the functioning of the central (CNS) and peripheral nervous system (PNS), including maturation and differentiation of neurons, formation of myelin, synthesis of catecholamines, modulation of neurotransmission and antioxidant protection. Neurological diseases and mental disorders are characterized by increased generation of free radicals. At the same time, the highest concentrations of vitamin C are found in the brain and neuroendocrine tissues. It is believed that vitamin C can affect the age of debut and the course of many neurological diseases and mental disorders. However, its potential therapeutic role continues to be studied. The efficacy and safety of vitamin C is likely influenced by the pharmacogenetic profile of the patient, including the carriage of single-nucleotide variants (SNVS), candidate genes associated with vitamin C metabolism in the human body in normal and neuropsychic disorders. The purpose of this thematic review is to update current knowledge about the role of vitamin C pharmacogenetics in the efficacy and safety of its use in neurological diseases (amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Huntington's disease, Alzheimer's disease, etc.) and mental disorders (depression, anxiety, schizophrenia, etc.). Special attention is paid to the possibility of translating the results of pharmacogenetic studies into real clinical practice in neurology and psychiatry.