bluuebunny/crossref_metadata_2025 huggingface dataset:
A new mixed-integer programming formulation for the maximally diverse grouping problem with attribute values
Authors: Schulz Arne
Published: May 2022

The paper presents a new mixed-integer programming formulation for the maximally diverse grouping problem (MDGP) with attribute values. The MDGP is the problem of assigning items to groups such that all groups are as heterogeneous as possible. In the version with attribute values, the heterogeneity of groups is measured by the sum of pairwise absolute differences of the attribute values of the assigned items, i.e. by the Manhattan metric. The advantage of the version with attribute values is that the objective function can be reformulated such that it is linear instead of quadratic like in the standard MDGP formulation. We evaluate the new model formulation for the MDGP with attribute values in comparison with two different MDGP formulations from the literature. Our model formulation leads to substantially improved computation times and solves instances of realistic sizes (for example the assignment of students to seminars) with up to 70 items and three attributes, 50 items and five attributes, and 30 items and ten attributes to (near) optimality within half an hour.
An adaptive meta-heuristic for music plagiarism detection based on text similarity and clustering
Authors: Malandrino Delfina , De Prisco Roberto , Ianulardo Mario , Zaccagnino Rocco
Published: May 2022

Plagiarism is a controversial and debated topic in different fields, especially in the Music one, where the commercial market generates a huge amount of money. The lack of objective metrics to decide whether a song is a plagiarism, makes music plagiarism detection a very complex task: often decisions have to be based on subjective argumentations. Automated music analysis methods that identify music similarities can be of help. In this work, we first propose two novel such methods: a text similarity-based method and a clustering-based method. Then, we show how to combine them to get an improved (hybrid) method. The result is a novel adaptive meta-heuristic for music plagiarism detection. To assess the effectiveness of the proposed methods, considered both singularly and in the combined meta-heuristic, we performed tests on a large dataset of ascertained plagiarism and non-plagiarism cases. Results show that the meta-heuristic outperforms existing methods. Finally, we deployed the meta-heuristic into a tool, accessible as a Web application, and assessed the effectiveness, usefulness, and overall user acceptance of the tool by means of a study involving 20 people, divided into two groups, one of which with access to the tool. The study consisted in having people decide which pair of songs, in a predefined set of pairs, should be considered plagiarisms and which not. The study shows that the group supported by our tool successfully identified all plagiarism cases, performing all tasks with no errors. The whole sample agreed about the usefulness of an automatic tool that provides a measure of similarity between two songs.
An autonomous lunar geophysical experiment package (ALGEP) for future space missions
Authors: Kawamura Taichi , Grott Matthias , Garcia Raphael , Wieczorek Mark , de Raucourt Sébastien , Lognonné Philippe , Bernauer Felix , Breuer Doris , Clinton John , Delage Pierre , Drilleau Mélanie , Ferraioli Luigi , Fuji Nobuaki , Horleston Anna , Kletetschka Günther , Knapmeyer Martin , Knapmeyer-Endrun Brigitte , Padovan Sebastiano , Plesa Ana-Catalina , Rivoldini Attilio , Robertsson Johan , Rodriguez Sebastien , Stähler Simon C. , Stutzmann Eleonore , Teanby Nicholas A. , Tosi Nicola , Vrettos Christos , Banerdt Bruce , Fa Wenzhe , Huang Qian , Irving Jessica , Ishihara Yoshiaki , Miljković Katarina , Mittelholz Anna , Nagihara Seiichi , Neal Clive , Qu Shaobo , Schmerr Nicholas , Tsuji Takeshi
Published: May 2022

Geophysical observations will provide key information about the inner structure of the planets and satellites and understanding the internal structure is a strong constraint on the bulk composition and thermal evolution of these bodies. Thus, geophysical observations are a key to uncovering the origin and evolution of the Moon. In this article, we propose the development of an autonomous lunar geophysical experiment package, composed of a suite of instruments and a central station with standardized interface, which can be installed on various future lunar missions. By fixing the interface between instruments and the central station, it would be possible to easily configure an appropriate experiment package for different missions. We describe here a series of geophysical instruments that may be included as part of the geophysical package: a seismometer, a magnetometer, a heat flow probe, and a laser reflector. These instruments will provide mechanical, thermal, and geodetic parameters of the Moon that are strongly related to the internal structure. We discuss the functionality required for future geophysical observations of the Moon, including the development of the central station that will be used commonly by different payloads.
Innovation in potentiometry: 3D-printed polylactic acid-based ion-selective bulk electrode membranes
Authors: Golcs Ádám , Vermes Brúnó , Siwek David Christopher , Huszthy Péter , Tóth Tünde
Published: May 2022

Although ion-selective membrane-based potentiometric sensors have already proved their analytical performance in several fields of life, their applicability is still limited in practice. Biodegradable, ionic additive-free, polylactic acid-based bulk electrode membrane matrix containing various environmentally friendly polyethylene glycol derivatives as plasticizer was developed for the first time to replace the conventional PVC-based ones. Moreover, the first introduction of 3D printing in potentiometric chemosensing was also reported. It was demonstrated that a thoroughly optimized and generalizable procedure for filament extrusion combined with 3D printing technology provides a unique tool for series production of the redesigned ion-selective bulk electrochemical membranes. Finally, the potentiometric detection of Hg2+ in water was carried out as a proof-of-concept study on sensing. Results showed an unexpected improvement in electrochemical characteristics of the novel membranes compared to their conventional analogues. The present work expanded the practical applicability of conventional potentiometric cation-selective electrode membranes enabling their green, decentralized, and automated state-of-the-art manufacturing using a novel matrix composition.

Graphical abstract
Early Social Behavior in Young Children with Sex Chromosome Trisomies (XXX, XXY, XYY): Profiles of Observed Social Interactions and Social Impairments Associated with Autism Spectrum Disorder (ASD)
Authors: Bouw Nienke , Swaab Hanna , Tartaglia Nicole , Cordeiro Lisa , van Rijn Sophie
Published: May 2022

Individuals with Sex Chromosome Trisomies (SCT; XXX, XXY, XYY) have an increased vulnerability for developing challenges in social adaptive functioning. The present study investigates social interaction behavior in the context of varying social load, and Autism Spectrum Disorder (ASD) symptomatology in young children aged 1–7.5 years old, with SCT (N = 105) and control children (N = 101). Children with SCT show less interaction behaviors and more social withdrawal, as compared to their control peers, which were most evident in the high social load condition. Second, social impairments related to ASD are more prevalent, as compared to controls (27.1% at clinical level). These findings stress the importance of early monitoring and (preventive) support of early social development in young children with SCT.
A study of the inclusion complex formed between cucurbit[8]uril and isonicotinic acid
Authors: Yu Zhi-chao , Lu Yun , Shan Pei-hui , Fan Ying , Tao Zhu , Xiao Xin , Wei Gang , Prior Timothy J. , Redshaw Carl
Published: May 2022

The complexation between cucurbit[8]uril, Q[8], and isonicotinic acid has been studied using 1H NMR spectroscopy, UV–Vis absorption spectroscopy, Raman spectroscopy and single crystal X-ray diffraction. The results revealed that the 2:1 inclusion complex (4-PA)2@Q[8]·25H2O is formed, with two guests simultaneously encapsulated in the hydrophobic cavity; the mean planes of the guests are 3.535 Å apart.

Graphical abstract
The Broken Promise of Institutional Psychiatry: Sexuality, Women and Mental Illness in 1950s Lebanon
Authors: Moghnieh Lamia
Published: May 2022

This article traces the case of Hala, a woman chronic patient of the Lebanon Hospital for Mental and Nervous Disorders (LHMND) in late 1950s Lebanon. Her story reveals a conglomeration of actors, expertise and technologies that regulated both her sexuality and mental illness, as she was moved, returned, then moved again, from the care of the family to the care of the psychiatric institution. By reconstructing an ethnographic case of the story of Hala, the article tackles an under-investigated area of research at the intersection of subjectivity, sexuality, psychiatry and family life. The case of Hala illustrates an on-going tension in defining and diagnosing mental illness for women between two forms of care: institutional psychiatry on one hand—promising a quick return of patients to society—and the family on the other, with its own understandings of what constitutes abnormality for women. Having lived at the hospital for more than twenty years, Hala’s voice and experience provide a powerful contribution to the ethnographic history of psychiatry in Lebanon. The article tackles questions on competing psychiatric and social authorities and the formation of psychiatric subjectivities. It also provides methodological and ethical reflections on the use of archives when conducting ethnographic research on psychiatry from the global peripheries. The case of Hala illustrates the patient’s own experience of LHMND’s policies of social rehabilitation in the late 1950s. It adds to a broader understanding of the processes that have led to the pathologizing of sexuality in under-studied societies such as Lebanon and the Middle East.
Spatial and seasonal patterns of water use in Mediterranean coastal dune vegetation
Authors: Zunzunegui María , Esquivias M. Paz , Gallego-Fernández Juan B.
Published: May 2022

Aims

This paper examines the water dynamics of a coastal dune plant community, addressing spatial and seasonal variations. We aimed to detect the patterns of water use by plants at the community level according to their distribution across a coastal dune gradient from beach to inland.

Methods

Five sites were established: upper beach, embryo-dune, slack, foredune, and inland. Eight perennial species were collected seasonally to analyse the isotopic composition and water potential. Soil water samples at 3 depths, groundwater, and atmosphere, were obtained to determine plant water sources.

Results

The species from Inland and foredune plant communities, Retama, Juniperus, and Helichrysum, showed the most stable isotopic signal throughout the year. On the contrary, the species most abundant on the upper beach, embryo-dune, and slack (Ammophila, Achillea, and Polygonum) showed the highest variability. Water deficit decreased the dependence on shallow and mid-soil layers along the beach-inland gradient. Beach and embryo-dune sites showed less negative leaf water potential values than the other positions in the dune gradient.

Conclusions

Three factors mark the proportion of water sources used for vegetation in coastal vegetation: community composition, distance to the sea, and seasonality. Coastal dune vegetation exhibited a species-specific response in water uptake that was modified by its location on the gradient. From upper beach to inland, the plant communities showed a slight progressive increase in the use of water from deeper layers. This pattern was similar and overlapped with the wet to dry seasonal pattern.
Constraints to agroforestry diffusion under the Billion Trees Afforestation Project (BTAP), Pakistan: policy recommendations for 10-BTAP
Authors: Ullah Ayat , Zeb Alam , Saqib Shahab E. , Kächele Harald
Published: May 2022

Effective agroforestry diffusion under the newly started 10-Billion Trees Afforestation Project (10-BTAP) needs a thorough understanding of the policy and implementation shortfalls of the already completed BTAP. This study examines the factors that affected the diffusion of the agroforestry in the Hindu-Kush Himalayan (HKH) region of Pakistan under BTAP. The data were gathered through in-depth interviews with Village Development Committee (VDC) members, Forest Department (FD) officials, and local farmers. Important factors positively affecting agroforestry diffusion included locations of crop fields on the river sides, community dependency on firewood, and market value of agroforestry timber. The logistic regression model shows that household head’s age, access to information, and area under cropland positively affected household level adoption of agroforestry under BTAP; forest cover was negatively related. In-depth interviews show that key barriers to FD in diffusion of agroforestry included provision of false information by farmers to monitoring teams, non-availability of extension staff, lack of communication among project staff and community, as well as a lack of sufficient budget for activities. Primary barriers to community adoption of agroforestry included no participation of VDCs in planning and monitoring of agroforestry programs, lack of plant need assessments on the part of the project staff, poor quality of plants distributed by FD, farmers’ poor know-how of plantations, lack of trust among community and project staff, as well as the waste of plants by farming community. Thus, this study recommends that policy-makers and project designers should consider these factors when planning agroforestry diffusion under 10-BTAP to improve its success.
Correlation between renal ablation zone in contrast-enhanced CT and non-enhanced MRI during the early period following percutaneous cryoablation
Authors: Umakoshi Noriyuki , Iguchi Toshihiro , Hiraki Takao , Matsui Yusuke , Tomita Koji , Uka Mayu , Kajita Soichiro , Araki Motoo , Mitsuhashi Toshiharu , Gobara Hideo , Kanazawa Susumu
Published: May 2022

Purpose

To retrospectively evaluate and correlate the contrast-enhanced computed tomography (CECT) and non-enhanced magnetic resonance imaging (MRI) during the early period following renal cryoablation.

Materials and methods

Both dynamic CECT and non-enhanced MRI were performed within 4 days following cryoablation in 34 renal tumors in 33 patients. The renal volumes of the unenhanced regions on dynamic CECT (nephrogenic phase, 4 mm thickness) and the regions with signal intensity changes on non-enhanced MRI (fat-suppressed T2-weighted image, 4 mm thickness) were evaluated. Fusion images of the axial, coronal, and sagittal sections of CECT and MRI images were created from the maximum cross-section of the renal tumor, and the match score of each image was visually evaluated on a 5-point scale.

Results

The mean renal volume of the unenhanced regions on CECT and those with signal intensity changes on non-enhanced MRI following cryoablation were 29.5 ± 19.9 cm3 (range, 4.3–97.4 cm3) and 30.7 ± 19.8 cm3 (range, 6.7–94.0 cm3), respectively; the difference between them was –1.17 cm3 (95% confidence interval [CI] –2.74, 0.40, P = 0.139). The Pearson’s product-moment correlation coefficient (r = 0.975; 95% CI, 0.951, 0.988; P < 0.0001) showed a strong correlation between the volumes. The average match score between CECT and non-enhanced MRI was as high as 4.5 ± 0.5 points (radiologist 1, 4.3 ± 0.5; radiologist 2, 4.7 ± 0.5). Local tumor control rate was 94.1% (32/34 tumors) and recurrence-free survival rate was 82.0% (95% CI: 64.2%, 91.5%) at 5 years.

Conclusions

The region with signal intensity changes on non-enhanced MRI was strongly correlated with the unenhanced region on CECT during the early period following renal cryoablation.
Addressing Peroxisome Proliferator-Activated Receptor-gamma in 3-Nitropropionic Acid-Induced Striatal Neurotoxicity in Rats
Authors: Mansour Riham M. , El Sayed Nesrine S. , Ahmed Maha A. E. , El-Sahar Ayman E.
Published: May 2022

Telmisartan (TEL) is an angiotensin II type 1 receptor blocker and a partial activator of peroxisome proliferator-activated receptor-gamma (PPARγ), which regulates inflammatory and apoptotic pathways. Increasing evidence has demonstrated the PPARγ agonistic property of TEL in several brain disorders. This study aims to explore the neuroprotective impact of TEL in 3-nitropropionic acid (3-NP)-induced neurotoxicity in rats. The PPARγ effect of TEL was affirmed by using the PPARγ agonist pioglitazone (PIO), and the antagonist GW9662. 3-NP led to a significant reduction in body weight alongside motor and cognitive functioning. The striata of the 3-NP-treated rats showed energy-deficit, microglia-mediated inflammatory reactions, apoptotic damage as well as histopathological lesions. PIO and TEL improved motor and cognitive perturbations induced by 3-NP, as confirmed by striatal histopathological examination, energy restoration, and neuronal preservation. Both drugs improved mitochondrial biogenesis evidenced by elevated mRNA expression of PPARγ, PGC-1α, and TFAM, alongside increased striatal ATP and SDH. The mitochondrial effect of TEL was beyond PPARγ activation. As well, their anti-inflammatory effect was attributed to suppression of microglial activation, and protein expression of pS536 p65 NF-κB with marked attenuation of striatal inflammatory mediator's release. Anti-inflammatory cytokine IL-10 expression was concurrently increased. TEL effectively participated in neuronal survival as it promoted phosphorylation of Akt/GSK-3β, further increased Bcl-2 expression, and inhibited cleavage of caspase-3. Interestingly, co-treatment with GW9662 partially revoked the beneficial effects of TEL. These findings recommend that TEL improves motor and cognitive performance, while reducing neuronal inflammation and apoptosis in 3-NP-induced neurotoxicity via a PPARγ-dependent mechanism.

Graphical Abstract
A notable bounded probability distribution for environmental and lifetime data
Authors: Bakouch Hassan S. , Hussain Tassaddaq , Chesneau Christophe , Jónás Tamás
Published: May 2022

In this article, we introduce a notable bounded distribution based on a modification of the epsilon function that creates an upper bound on the domain of a distribution. Further, a key feature of the distribution is to have asymptotic connections with the famous Lindley distribution, which is a weighted variant of the exponential distribution and also a mixture of exponential and gamma distributions. In some ways, the proposed distribution provides a flexible solution to the modeling of bounded characteristics that can be almost well-fitted by the Lindley distribution if the domain is restricted. Moreover, we have also explored its application, particularly with reference to lifetime and environmental points of view, and found that the proposed model exhibits a better fit among the competing models. Namely, we demonstrate the practical applicability of the new distribution on two data sets containing lifetime data, as well as on two other data sets of rainfall data. Further, from the annual rainfall analysis, the proposed model exhibits a realistic return period of the rainfall.
A bi-objective blood supply chain model under uncertain donation, demand, capacity and cost: a robust possibilistic-necessity approach
Authors: Ghahremani-Nahr Javid , Kian Ramez , Sabet Ehsan , Akbari Vahid
Published: May 2022

This paper addresses a multi-objective blood supply chain network design, considering economic and environmental aspects. The objective of this model is to simultaneously minimize a blood supply chain operational cost and its logistical carbon footprint. In order to embed the uncertainty of transportation costs, blood demand, capacity of facilities and carbon emission, a novel robust possibilistic-necessity optimization used regarding a hybrid optimistic-pessimistic form. For solving our bi-objective model, three multi-objective decision making approaches including LP-metric, Goal-Programming and Torabi- Hassini methods are examined. These approaches are assessed and ranked with respect to several attributes using a statistical test and TOPSIS method. Our proposed model can accommodate a wide range of decision-makers’ viewpoints with the normalized objective weights, both at the operational or strategic level. The trade-offs between the cost and carbon emission for each method has been depicted in our analyses and a Pareto frontier is determined, using a real case study data of 21 cities in the North-West of Iran considering a 12-month implementation time window.
Analysis of clinical characteristics of children with Aicardi-Goutieres syndrome in China
Authors: Wang Wei , Wang Wei , He Ting-Yan , Zou Li-Ping , Li Wen-Dao , Yu Zhong-Xun , Ma Ming-Sheng , Yang Jun , Song Hong-Mei
Published: May 2022

Background

Aicardi-Goutieres syndrome (AGS) is an inflammatory disorder belonging to the type I interferonopathy group. The clinical diagnosis of AGS is difficult, which can lead to a high mortality rate. Overall, there is a lack of large-sample research data on AGS in China. We aim to summarize the clinical characteristics of Chinese patients with AGS and provide clues for clinical diagnostic.

Methods

The genetic and clinical features of Chinese patients with AGS were collected. Real-time polymerase chain reaction was used to detect expression of interferon-stimulated genes (ISGs).

Results

A total of 23 cases were included, consisting of 7 cases of AGS1 with three prime repair exonuclease 1 mutations, 3 of AGS2 with ribonuclease H2 subunit B (RNASEH2B) mutations, 3 of ASG3 with RNASEH2C, 1 of AGS4 with RNASEH2A mutations, 2 of AGS6 with adenosine deaminase acting on RNA 1 mutations, and 7 of AGS7 with interferon induced with helicase C domain 1 mutations. Onset before the age of 3 years occurred in 82.6%. Neurologic involvement was most common (100%), including signs of intracranial calcification which mainly distributed in the bilateral basal ganglia, leukodystrophy, dystonia, epilepsy, brain atrophy and dysphagia. Intellectual disability, language disability and motor skill impairment were also observed. Skin manifestations (60.87%) were dominated by a chilblain-like rash. Features such as microcephaly (47.62%), short stature (52.38%), liver dysfunction (42.11%), thyroid dysfunction (46.15%), positive autoimmune antibodies (66.67%), and elevated erythrocyte sedimentation rate (53.85%) were also found. The phenotypes of 2 cases fulfilled the diagnostic criteria for systemic lupus erythaematosus (SLE). One death was recorded. ISGs expression were elevated.

Conclusions

AGS is a systemic disease that causes sequelae and mortality. A diagnosis of AGS should be considered for patients who have an early onset of chilblain-like rash, intracranial calcification, leukodystrophy, dystonia, developmental delay, positive autoimmune antibodies, and elevated ISGs, and for those diagnosed with SLE with atypical presentation who are nonresponsive to conventional treatments. Comprehensive assessment of vital organ function and symptomatic treatment are important.
Sources and Fate of Organic Carbon in West Spitsbergen Fjord Systems: A Review
Authors: Saalim Syed Mohammad , Choudhary Shabnam , Mohan Rahul
Published: May 2022

Fjord margins in the high latitude regions are the hotspots for long term carbon burial. Studying the source and fate of organic carbon in high latitude fjords would help assess the sedimentary processes and burial. With the unprecedented warming, the marine productivity patterns are changing, leading to changes in the sources of organic carbon and its eventual burial in marine sediments. In the present study, high latitude fjords in the West Spitsbergen region has been reviewed, subjected to competing effects of large freshwater influx from the glacial melts, enhanced West Spitsbergen Current and its control on marine productivity. The West Spitsbergen Current advects warm North Atlantic waters enriched in nutrients to the fjords in the West Spitsbergen region. The increased freshwater from the glacial melts also dominates the fjords. Thus, the composition of organic matter in the fjord is mainly controlled by the inflow of freshwater from the glaciers and intrusion of oceanic waters to the fjords influencing the organic matter stability and carbon burial efficiency in the fjord sediments. The ongoing rapid warming in the Arctic changes the hydrographic settings, and changes in the strength of West Spitsbergen Current may also influence the long-term organic carbon burial in the West Spitsbergen fjords.
Improving Prospective Teachers’ Beliefs About a Double Discontinuity Between School Mathematics and University Mathematics
Authors: Eichler Andreas , Isaev Viktor
Published: May 2022

Prospective teachers often perceive a “double discontinuity” between school mathematics and university mathematics. The first discontinuity can be described as the belief that there is no coherence between school mathematics and university mathematics, which forms part of the notoriously problematic transition from school to university. The second discontinuity can be described as a belief about the lack of relevance of university mathematics for the later professional practice of prospective teachers. Beliefs about coherence and relevance have been known to impact prospective mathematics teachers’ interests and academic success. In this paper, we discuss an intervention involving 72 prospective secondary school mathematics teachers, aimed at influencing their beliefs about coherence and relevance. For this, we refer to the construct of beliefs as the main part of our theoretical framework, as well as the sub-constructs of beliefs regarding coherence and relevance. We then describe an intervention implemented within the first two years of mathematics courses, involving so-called “teacher-oriented” tasks that aim to trigger reflection on the benefit of university mathematics for teaching mathematics in school. The effect of the intervention was measured with a pretest-posttest experimental design using a questionnaire concerning teachers’ beliefs about coherence and relevance. Our results show that the prospective teachers’ beliefs about coherence and relevance generally decrease during the semester. However, statistically significant differences between the treatment group and a control group were found, especially regarding their beliefs about relevance.
Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine
Authors: Koklesova Lenka , Mazurakova Alena , Samec Marek , Kudela Erik , Biringer Kamil , Kubatka Peter , Golubnitschaja Olga
Published: May 2022

Mitochondria are the “gatekeeper” in a wide range of cellular functions, signaling events, cell homeostasis, proliferation, and apoptosis. Consequently, mitochondrial injury is linked to systemic effects compromising multi-organ functionality. Although mitochondrial stress is common for many pathomechanisms, individual outcomes differ significantly comprising a spectrum of associated pathologies and their severity grade. Consequently, a highly ambitious task in the paradigm shift from reactive to predictive, preventive, and personalized medicine (PPPM/3PM) is to distinguish between individual disease predisposition and progression under circumstances, resulting in compromised mitochondrial health followed by mitigating measures tailored to the individualized patient profile. For the successful implementation of PPPM concepts, robust parameters are essential to quantify mitochondrial health sustainability. The current article analyses added value of Mitochondrial Health Index (MHI) and Bioenergetic Health Index (BHI) as potential systems to quantify mitochondrial health relevant for the disease development and its severity grade. Based on the pathomechanisms related to the compromised mitochondrial health and in the context of primary, secondary, and tertiary care, a broad spectrum of conditions can significantly benefit from robust quantification systems using MHI/BHI as a prototype to be further improved. Following health conditions can benefit from that: planned pregnancies (improved outcomes for mother and offspring health), suboptimal health conditions with reversible health damage, suboptimal life-style patterns and metabolic syndrome(s) predisposition, multi-factorial stress conditions, genotoxic environment, ischemic stroke of unclear aetiology, phenotypic predisposition to aggressive cancer subtypes, pathologies associated with premature aging and neuro/degeneration, acute infectious diseases such as COVID-19 pandemics, among others.
Patterned glass ceramic design for high-brightness high-color-quality laser-driven lightings
Authors: Huang Qiugui , Lin Hang , Wang Bo , Lin Shisheng , Wang Pengfei , Sui Ping , Xu Ju , Cheng Yao , Wang Yuansheng
Published: May 2022

Up-to-date laser-driven lightings confront a challenge of simultaneously achieving good photometric and chromatic performances. Herein, the coupling of “patterned package design” and “phosphor wheel” was proposed and demonstrated effectively to deal with this tough issue, based on a new architecture of CaAlSiN3:Eu2+ (CASN:Eu) glass ceramic film (GCF) on Y3Al5O12:Ce3+ (YAG:Ce) GC plate. The fabricated composite has no interface between the two functional layers and retains the admirable luminescent features from CASN:Eu and YAG:Ce for the microstructural integrity during co-sintering. The studies on laser-microcrystalline interactions reveal that the luminescence saturation is almost determined by thermal quenching for YAG:Ce, but is ascribed to thermal/intensity quenching which are equally crucial for CASN:Eu. Benefiting from the elaborate architecture design, good color chromaticity tunability was obtained, and severe photon reabsorption was reduced. Moreover, accompanied with the rotation induced increase of thermal convection to air and pulse-like excitation, the constructed lighting engine under blue laser driven shows bright white light with luminous flux (LF) higher than 1000 lm, adjustable chromaticity from cool to warm, and improved color rendering index (CRI) approaching to 70.
External validation of a deep-learning model to predict severe acute kidney injury based on urine output changes in critically ill patients
Authors: Alfieri Francesca , Ancona Andrea , Tripepi Giovanni , Randazzo Vincenzo , Paviglianiti Annunziata , Pasero Eros , Vecchi Luigi , Politi Cristina , Cauda Valentina , Fagugli Riccardo Maria
Published: May 2022

Objectives

The purpose of this study was to externally validate algorithms (previously developed and trained in two United States populations) aimed at early detection of severe oliguric AKI (stage 2/3 KDIGO) in intensive care units patients.

Methods

The independent cohort was composed of 10'596 patients from the university hospital ICU of Amsterdam (the “AmsterdamUMC database”) admitted to their intensive care units. In this cohort, we analysed the accuracy of algorithms based on logistic regression and deep learning methods. The accuracy of investigated algorithms had previously been tested with electronic intensive care unit (eICU) and MIMIC-III patients.

Results

The deep learning model had an area under the ROC curve (AUC) of 0,907 (± 0,007SE) with a sensitivity and specificity of 80% and 89%, respectively, for identifying oliguric AKI episodes. Logistic regression models had an AUC of 0,877 (± 0,005SE) with a sensitivity and specificity of 80% and 81%, respectively. These results were comparable to those obtained in the two US populations upon which the algorithms were previously developed and trained.

Conclusion

External validation on the European sample confirmed the accuracy of the algorithms, previously investigated in the US population. The models show high accuracy in both the European and the American databases even though the two cohorts differ in a range of demographic and clinical characteristics, further underlining the validity and the generalizability of the two analytical approaches.

Graphical abstract
Is There a Kuznets Curve for CO2-Emissions?
Authors: Hannesson Rögnvaldur
Published: May 2022

The history of the environmental Kuznets curve is traced. We estimate how the CO2-intensity of economies is related to GDP per capita and examine the implications for the Kuznets curve. We find mixed evidence for the existence of this curve. In many poor and medium rich countries the CO2-intensity has increased since 1990, while in rich countries it has fallen. In some of those it has fallen at an increasing rate, but in others at a declining rate. If the CO2-intensity converges to a lower limit as countries grow richer the Kuznets curve would not exist.
Immaterial Texts in Late Medieval England
Authors: Wakelin Daniel
Published: May 2022

Daniel Wakelin introduces and reinterprets the misunderstood and overlooked craft practices, cultural conventions and literary attitudes involved in making some of the most important manuscripts in late medieval English literature. In doing so he overturns how we view the role of scribes, showing how they ignored or concealed irregular and damaged parchment; ruled pages from habit and convention more than necessity; decorated the division of the text into pages or worried that it would harm reading; abandoned annotations to poetry, focusing on the poem itself; and copied English poems meticulously, in reverence for an abstract idea of the text. Scribes' interest in immaterial ideas and texts suggests their subtle thinking as craftspeople, in ways that contrast and extend current interpretations of late medieval literary culture, 'material texts' and the power of materials. For students, researchers and librarians, this book offers revelatory perspectives on the activities of late medieval scribes.
Change in Global Environmental Politics
Authors: Manulak Michael W.
Published: May 2022

As wildfires rage, pollution thickens, and species disappear, the world confronts environmental crisis with a set of global institutions in urgent need of reform. Yet, these institutions have proved frustratingly resistant to change. Introducing the concept of Temporal Focal Points, Manulak shows how change occurs in world politics. By re-envisioning the role of timing and temporality in social relations, his analysis presents a new approach to understanding transformative phases in international cooperation. We may now be entering such a phase, he argues, and global actors must be ready to realize the opportunities presented. Charting the often colorful and intensely political history of change in global environmental politics, this book sheds new light on the actors and institutions that shape humanity's response to planetary decline. It will be of interest to scholars and advanced students of international relations, international organization and environmental politics and history.
Experimental Thinking
Authors: Druckman James N.
Published: May 2022

Experiments are a central methodology in the social sciences. Scholars from every discipline regularly turn to experiments. Practitioners rely on experimental evidence in evaluating social programs, policies, and institutions. This book is about how to “think” about experiments. It argues that designing a good experiment is a slow moving process (given the host of considerations) which is counter to the current fast moving temptations available in the social sciences. The book includes discussion of the place of experiments in the social science process, the assumptions underlying different types of experiments, the validity of experiments, the application of different designs, how to arrive at experimental questions, the role of replications in experimental research, and the steps involved in designing and conducting “good” experiments. The goal is to ensure social science research remains driven by important substantive questions and fully exploits the potential of experiments in a thoughtful manner.
The Life of Nobuko
Authors: Kanasaka Kiyonori
Published: May 2022

Kiyonori Kanasaka,
a distinguished geographer at Kyoto University, is widely
recognized as Japan’s leading researcher on the Victorian
traveller Isabella Bird. He has published extensively in
Japanese on the subject, including a full annotated translation
of the original two-volume edition of Unbeaten
Tracks. He is known worldwide for his ‘Twin Time
Travel’ photographic exhibition, shown in many countries -
presenting Bird’s descriptions of what she wrote about in her
books in juxtaposition with illustrations of the
present.
The View from Jaketown: Considering Variation in the Poverty Point Culture of the Lower Mississippi Valley
Authors: Ward Grace M. V. , Grooms Seth B. , Schroll Andrew G. , Kidder Tristram R.
Published: May 2022

Recent research at Jaketown, a Late Archaic earthwork site in the Lower Mississippi Valley, suggests that the culture-historical framework used to interpret Jaketown and contemporary sites in the region obscures differences in practices across sites. As an alternative, we propose a framework focused on variation in material culture, architecture, and foodways between Jaketown and Poverty Point, the regional type site. Our analysis indicates that people used Poverty Point Objects and imported lithics at Jaketown by 4525–4100 cal BP—earlier than elsewhere in the region. By 3450–3350 cal BP, people intensively occupied Jaketown, harvesting a consistent suite of wild plants. Between 3445 and 3270 cal BP, prior to the apex of earthwork construction at Poverty Point, the community at Jaketown built at least two earthworks and multiple post structures before catastrophic flooding sometime after 3300 cal BP buried the Late Archaic landscape under alluvium. These new data lead us to conclude that the archaeological record of the Late Archaic Lower Mississippi Valley does not reflect a uniform regional culture. Rather, relationships between Jaketown and Poverty Point indicate a multipolar history in which communities selectively participated in larger social phenomena—such as exchange networks and architectural traditions—while maintaining diverse, localized practices.
Leonard Rockshelter Revisited: Evaluating a 70-Year-Old Claim of a Late Pleistocene Human Occupation in the Western Great Basin
Authors: Smith Geoffrey M. , Sturtz Sara , Camp Anna J. , Adams Kenneth D. , Kallenbach Elizabeth , Rosencrance Richard L. , Hughes Richard E.
Published: May 2022

Robert Heizer excavated Leonard Rockshelter (26Pe14) in western Nevada more than 70 years ago. He described stratified cultural deposits spanning the Holocene. He also reported obsidian flakes purportedly associated with late Pleistocene sediments, suggesting that human use extended even farther back in time. Because Heizer never produced a final report, Leonard Rockshelter faded into obscurity despite the possibility that it might contain a Clovis Era or older occupation. That possibility prompted our team of researchers from the University of Nevada, Reno and Desert Research Institute to return to the site in 2018 and 2019. We relocated the excavation block from which Heizer both recovered the flakes and obtained a late Pleistocene date on nearby sediments. We minimally excavated undisturbed deposits to rerecord and redate the strata. As an independent means of evaluating Heizer's findings, we also directly dated 12 organic artifacts housed at the Phoebe A. Hearst Museum of Anthropology. Our work demonstrates that people did not visit Leonard Rockshelter during the late Pleistocene. Rather, they first visited the site immediately following the Younger Dryas (12,900–11,700 cal BP) and sporadically used the shelter, mostly to store gear, throughout the Holocene.
The Good International Citizen
Authors: Horner David , Connor John
Published: May 2022

Volume 3 of the official history of Australian peacekeeping, humanitarian and post-cold war operations explores Australia's involvement in six overseas missions following the end of the Gulf War: Cambodia (1991–99); Western Sahara (1991–94); the former Yugoslavia (1992–2004); Iraq (1991); Maritime Interception Force operations (1991–99); and the contribution to the inspection of weapons of mass destruction facilities in Iraq (1991–99). These missions reflected the increasing complexity of peacekeeping, as it overlapped with enforcement of sanctions, weapons inspections, humanitarian aid, election monitoring and peace enforcement. Granted full access to all relevant Australian Government records, David Horner and John Connor provide readers with a comprehensive and authoritative account of Australia's peacekeeping operations in Asia, Africa and Europe.
Global Strichartz estimates for the Dirac equation on symmetric spaces
Authors: Ben-Artzi Jonathan , Cacciafesta Federico , de Suzzoni Anne-Sophie , Zhang Junyong
Published: May 2022

In this paper, we study global-in-time, weighted Strichartz estimates for the Dirac equation on warped product spaces in dimension

$n\geq 3$

. In particular, we prove estimates for the dynamics restricted to eigenspaces of the Dirac operator on the compact spin manifolds defining the ambient manifold under some explicit sufficient condition on the metric and estimates with loss of angular derivatives for general initial data in the setting of spherically symmetric and asymptotically flat manifolds.
Bounds for spectral projectors on tori
Authors: Germain Pierre , Rydin Myerson Simon L.
Published: May 2022

We investigate norms of spectral projectors on thin spherical shells for the Laplacian on tori. This is closely related to the boundedness of resolvents of the Laplacian and the boundedness of$L^{p}$norms of eigenfunctions of the Laplacian. We formulate a conjecture and partially prove it.
‘Congruent We Govern’: Cost of Governance in Multiparty Presidentialism
Authors: Pereira Carlos , Bertholini Frederico , Melo Marcus
Published: May 2022

The received wisdom on executive–legislative relations in multiparty presidential systems is that the size of the president's majority in Congress is the key factor explaining governance patterns, particularly the president's legislative success. However, in many cases presidents enjoying a nominal majority have been unable to pass legislation and have faced institutional instability. The article departs from a conventional definition of divided government and focuses on the preference incongruence between the governing coalition and the floor of Congress. It argues that the ideological distance between the floor and the coalition is a key factor explaining the president's cost of governing (which includes factors such as the distribution of cabinet portfolios and budgetary transfers to coalition partners). The article provides an empirical test with data from Brazil that find that the greater the ideological incongruence, the higher the cost of governing for the president.
A Pregnant Pause: Pregnancy, Miscarriage, and Suspended Time
Authors: Browne Victoria
Published: May 2022

This article takes the rupturing of normative, linear, reproductive time that occurs in the event of miscarriage as a potentially generative philosophical moment—a catalyst to rethink pregnancy aside from the expectation of child-production. Pregnant time is usually imagined as a linear passage toward birth. Accordingly, the one who “miscarries” appears as suspended within an arrested journey that never arrived at its destination, or indeed, as ejected from pregnant time altogether. But here I propose to rethink both pregnancy and miscarriage through the lens of “suspended time”—a theoretical move that shifts the accent from the future as the dominating frame of reference to the lived present. Drawing on work by Kathryn Bond Stockton, Lauren Berlant, Lisa Baraitser, and others, the article explores overlooked temporalities of pregnancy and miscarriage that operate not in the mode of futural projection or futural loss, but rather through present-oriented forms of adjustment and sensing, attachment and intimacy, maintenance and care. By “suspending the future,” then, we can resist the oppositional framing of pregnancy and miscarriage, because if pregnant time is not represented in exclusively future-oriented terms as being-toward-birth, then miscarriage need not be understood as pregnancy'sundoing.
Studies on the History of Dutch Sinology: A Bibliographical Essay
Authors: Idema Wilt L.
Published: May 2022

Despite the long Dutch presence in Taiwan (1624–1662) and the active trade between Batavia and China in the eighteenth century, the Dutch tradition of academic Sinology got underway only in the last quarter of the nineteenth century, when the training of future officers for Chinese affairs in the Dutch East Indies was moved to Leiden. This training (often including an extended period of stay in China) remained the main task of Chinese teaching at Leiden until 1949, when Indonesia achieved independence. The earliest phase of Chinese teaching at Leiden has received an encyclopedic coverage in the work of Koos Kuiper. Scholars of the second generation who have received monographic treatment include J.J.M. de Groot and Henri Borel. The best-known Dutch Sinologist of the middle of the twentieth century was Robert Hans van Gulik who was not only a successful diplomat and highly original scholar, but also established an international reputation with his Judge Dee crime novels. His work has given rise to considerable scholarship in English and Chinese.
A new species of Dermadena (Digenea: Lepocreadiidae) from the stone triggerfish Pseudobalistes naufragium (Tetraodontiformes: Balistidae) in the South American Pacific Ocean
Authors: Simões R.O. , Chero J.D. , Cruces C.L. , Sáez G.M. , Maldonado A. , Luque J.L.
Published: May 2022

The present paper describes a new species of Dermadena (Digenea) parasitizing Pseudobalistes naufragium in Puerto Pizarro, northern Peru, using light and scanning electronic microscopy (SEM). Additionally, molecular analysis was also performed to determine the phylogenetic affinities of Dermadena within the Lepocreadiidae. The new species is differentiated from Dermadena spatiosa, Dermadena stirlingi and Dermadena lactophrysi by presenting a curved and well-developed external seminal vesicle. Also, SEM revealed numerous dome-shaped tegument protuberances forming glandular papillae with transversal wrinkles arranged roughly in concentric rows around the acetabular region, varying in size from large at the middle of the body to small at the margin. In the molecular phylogeny, the new species formed a well-supported clade with sequences of species from the Lepocreadiidae, confirming that it belongs to this family.