bluuebunny/crossref_metadata_2025 huggingface dataset:
Las Game Jams como método educativo para fomentar la igualdad de género en el sector del videojuego
Authors: Barranco Crespo María Teresa
Published: October 2024

En los últimos años, se ha incrementado la atención sobre el papel de las mujeres en la industria de los videojuegos, y desde la educación superior se promueven metodologías inclusivas para crear entornos más equitativos. Este estudio tiene como objetivoanalizar la participación femenina en eventos como las Game Jams, con el fin de mejorar los entornos de aprendizaje y ajustar tácticas pedagógicas eficaces. La investigación, de enfoque cuantitativo descriptivo, muestra que las percepciones estudiantiles son cada vez más neutrales respecto al género, destacando relaciones más equitativas en estos espacios. En parte, este avance puede atribuirse a las prácticas colaborativas, que no solo fomentan la participación, sino también la socialización. Sin embargo, persiste una brecha significativa de género en la industria de los videojuegos, donde las mujeres continúan siendo una minoría en comparación con los hombres. Esta disparidad subraya la necesidad de implementar políticas de igualdad de género, promover la diversidad en todos los niveles y fomentar una cultura laboral respetuosa y libre de acoso para abordar este desequilibrio.
Territórios, temporalidades, atenção à saúde e Covid-19: dimensão nacional e internacional
Authors: Santos Boás dos
Published: October 2024

A presente resenha visa apresentar ao leitor uma visão geral sobre o conteúdo da obra Territórios, temporalidades, atenção à saúde e Covid-19: dimensão nacional e internacional, sob a organização da Prof.ª Dr.ª Edna Maria Goulart Joazeiro, publicada pela Editora EDUFPI em 2024. Vale destacar previamente que é de fato uma coletânea de relevância indiscutível para o campo de pesquisa humano-social, especialmente na área da saúde, pois examina as interseções entre saúde, território e temporalidade no contexto da pandemia da Covid-19.
Professores de matemática em formação inicial
Authors: Silva Maria Marta da , Cedro Wellington Lima
Published: October 2024

O objetivo desse artigo é investigar como professores de Matemática em formação inicial se apropriaram da avaliação como elemento da atividade pedagógica. As discussões se sustentaram nos pressupostos da Teoria Histórico-Cultural. A opção metodológica foi o experimento formativo, o mesmo perdurou um ano letivo. Os sujeitos eram dez alunos matriculados na disciplina de Estágio Supervisionado da Licenciatura de Matemática. Destaca-se que os professores em formação dão indícios de apreensão da avaliação como aspecto constituinte da atividade pedagógica. Os sujeitos também compreendem que a avaliação está presente na interdependência entre planejamento e conteúdo. Igualmente a reconhecem na relação entre os processos de ensino e aprendizagem.
One-pot synthesis of carbon dots/hydrochar and visible-light-driven photocatalysts for aerobic oxidative coupling of benzylic amines
Authors: Cao Xihua , Zhao Yi , Leng Junyang , Bai Xiaoli , Qu Yining , Jiang Liang , Chen Daomei , Wang Jiaqiang
Published: October 2024

Utilizing selective photocatalysis conversion of amines represents an environmentally sustainable and economically feasible approach to generating valuable chemical products in the industry. Herein, carbon dots (CDs) incorporated in hydrochar (CDs/HCPP) were synthesized by one-pot hydrothermal carbonization of pomelo peel (PP) coupled with freeze-drying and used for aerobic oxidative coupling of benzylic amines. CDs were produced using only the pomelo peel as the carbon source, without the addition of any extra carbon additives. CDs/HCPP exhibited the greatest catalytic activity, achieving a benzylamine conversion rate of 99%, which was nearly 5.5 times of carbonized PP (CPP) without CDs and 1.14 times of CDs alone. Additionally, the oxidation of other amines, such as p -substituted benzylamines with groups that donate and withdraw electrons, was also demonstrated to be highly active and reusable using CDs/HCPP. This study has the potential to pave the way for novel methodologies and insights into synthesizing biomass composites adorned with CDs, enhancing the efficacy of photocatalytic syntheses.
Molecular dynamics simulations of nanoparticle sintering in additive nanomanufacturing: insights from sintering mechanisms
Authors: Jamshideasli Dourna , Shamsaei Nima , Mahjouri-Samani Masoud , Shao Shuai
Published: October 2024

The sintering behavior of nanoparticles (NPs), which determines the quality of additively nanomanufactured products, differs from conventional understanding established for microparticles. As NPs have a high surface-to-volume ratio, they are subjected to a higher influence from surface tension and a lower melting point than microparticles, resulting in variations in both crystallographic defect-mediated and surface diffusion mechanisms. Meanwhile, the interplay between these controlling mechanisms in NPs has not been well understood, primarily because sintering occurs on the nanosecond timescale, making it an exceptionally transient process. In this work, sintering of both equal and unequal sized Ag and Cu NP doublets with and without misorientation (both tilt and twist) is modeled through molecular dynamics (MD) simulations. The formation and evolution of crystallographic defects, such as vacancies, dislocations, stacking faults, twin boundaries, and grain boundaries, during sintering are investigated. The influence of these defects on plastic deformation and diffusion mechanisms, such as volume diffusion and grain boundary (GB) diffusion, is discussed to elucidate the responsible sintering mechanisms. The surface diffusion mechanism is visualized by using detailed atomic trajectories generated during the sintering process. Finally, the overall effectiveness of all diffusion sintering mechanisms is quantified. This study provides first insights into the complexity and dynamics of NP sintering mechanisms which can aid in the development of accurate predictive models.
CUBIC SPLINE INTERPOLATION TO APPROXIMATE SEA DEPTH BETWEEN TELUK SUAK AND LEMUKUTAN ISLAND
Authors: Hariski Muhammad , Kusumastuti Nilamsari , Yudhi Yudhi
Published: October 2024

Interpolation is a technique that determines the value of a function at a point located between several known data points. Various interpolation methods include polynomial interpolation, Lagrange interpolation, Newton interpolation, and spline interpolation. Cubic spline interpolation aims to produce accurate approximations characterized by minimal oscillations in the resulting curve. This research uses the cubic spline interpolation method to estimate the sea depth in the waters between Teluk Suak and Pulau Lemukutan. The sea depth measurements are conducted to acquire information regarding the underwater topography. We collected data points using remote sensing techniques through Google Earth Pro. These points are selected based on the sea depth profile considerations, including steep areas and points of depth variation to maintain the seabed conditions within the interpolation curve, with a total of 31 data points. Subsequently, we subjected these data points to the conditions necessary for cubic spline interpolation, resulting in a system of 120 linear equations. After solving this system of linear equations, we obtained cubic spline interpolation polynomials for each subinterval and then estimated the sea depth at other points. Based on the cubic spline interpolation results, we achieved a Mean Average Percentage Error (MAPE) of 1.58%, indicating a highly accurate interpolation outcome.
MODEL INVESTASI POLIS ASURANSI JIWA BERBONUS TIPE DWIGUNA DENGAN AMERICAN PUT OPTION
Authors: Lissa Hermei , Putri Endah R.M.
Published: October 2024

Insurance is a form of protection against the concept of risk transfer that may occur from an uncertain event. One type of insurance is life insurance. With the changing times, life insurance launched innovative products, one of which is endowment life insurance. Endowment life insurance is a type of life insurance that provides compensation benefits if the policy holder dies during the coverage period, as well as providing cash value and bonuses if the policy holder is still alive until the end of the period. This study aims to determine the fair price of insurance policies and the price of bonus life insurance policies. Determination of the value of the American put option with the binomial method using a numerical approach, the formulation of the portfolio model includes determining the model of the unit price with Geometric Brownian Motion, solving using Black-Scholes, determining the structure of the bonus life insurance policy with the formulation of a single premium payment, bonus rate, and benefits. then analyze the movement of the price of a reasonable bonus life insurance policy with a surrender option based on the age of the insured, technical rate, participation level, and volatility. The surrender value obtained is the difference between the value of the American Put option and the European Call Option. Based on the simulation, the conclusion of this analysis is that the price of the endowment type life insurance policy can be estimated using the binomial method at around 0.78 for a fair policy price and around 0.27 for a policy price with a surrender option. This gives an idea of the relative value of the policy price to the expected benefits under certain conditions, such as the death of the insured in the first year of the contract.
Stress oxidativo e infertilidade: uma revisão narrativa
Authors:   Clínica Ergo,  Reprodución, Ginecología  y Obstetrica,  Avenida de Portugal  96-98-100, Gijón,  Asturias, Espanha, 33207, Guimarães Marcela Rodrigues Moreira , de Oliveira Marie ,   Nutrition Academy, Consiglieri Park, Estrada  Consiglieri Pedroso, n.º 71,  Edifício D, 5.º Dir., 2730-055 Queluz de  Baixo, Portugal, Silva Ana Rita ,   Centro de Investigação  Interdisciplinar Egas  Moniz (CiiEM) do Instituto  Universitário Egas Moniz,  Campus Universitário,  Quinta da Granja, Monte  da Caparica, 2829-511 Caparica,  Portugal
Published: October 2024

A infertilidade é uma doença do sistema reprodutivo masculino e/ou feminino definida pela incapacidade de atingir uma gravidez após 12 meses ou mais de relações sexuais regulares desprotegidas. A etiopatogénese pode estar associada ao estilo de vida moderno ou a alterações metabólicas, que se observam frequentemente com o aumento da idade materna, obesidade, diabetes, ansiedade, consumo de álcool, tabaco e exposição aos poluentes ambientais, incluindo os que atuam como desreguladores endócrinos. Um fator comum a estas condições é a produção excessiva de espécies reativas de oxigénio que podem dar origem ao stress oxidativo. Assim, o objetivo da presente revisão de literatura é estudar a existência de uma associação entre o stress oxidativo e a incidência de infertilidade. A pesquisa foi realizada na base de dados Pubmed, entre fevereiro e abril de 2023. Utilizou-se como palavras chave: ¨oxidative stress¨, ¨fertility¨. ¨infertility¨, ¨female infertility¨ e ¨male infertility¨. No que diz respeito ao sistema reprodutor, o stress oxidativo pode afetar a qualidade dos gâmetas, oócitos, espermatozoides, embriões e os ambientes respetivos. Adicionalmente, afeta o desenvolvimento embrionário precoce e a implantação, o que por sua vez pode comprometer a taxa de gravidez. Por fim, tem ainda sido associado negativamente à estimulação ovariana, e consequentemente ao potencial desenvolvimento de oócitos na fertilização in vitro. Neste sentido, a partir da presente revisão, torna-se possível afirmar que o stress oxidativo desempenha um papel importante na infertilidade feminina e masculina, constituindo implicações claras para a prevenção, diagnóstico e resolução terapêutica de tais condições.
Remote monitoring of cathodic protection systems on navigable waterways
Authors: Becerra-Stasiewicz, Natalie , Gerios Veronica , Mayer Christina , Morefield Sean
Published: October 2024

Cathodic protection is one of the main modes of corrosion prevention for structures in navigable waterways. The rectifier output voltage must be in a specific range to provide effective protection against corrosion. This effort was designed to monitor, predict, and stabilize the efficacy of multiple cathodic protection systems. Copper/copper-sulfate half-cell electrode sensors, water quality sensors, and gauges for rectifier output were connected to modems at multiple locks so the data could be analyzed to create a predictive maintenance algorithm.
AN ANALYSIS ON CODE–SWITCHING IN RACHEL GODDARD’S YOUTUBE CHANNEL
Authors: Dharmayanti Ni Luh Putu Diah Ayu Sri Dharmayanti Diah
Published: October 2024

Code-switching is the use of two different languages in the same utterance, either between turns or inside a single expression or sentence. The purpose of this study was to identify the types of code-switching and the function of code-switching as it appeared in Rachel Goddard's videos. This study focused only on Indonesian to English code-switching. The data were taken from one of makeup videos of Rachel Goddard YouTube channel. The method used in this study was qualitative research and the technique to collect the data was the documentation method. The main theory used in this study was the theory from Hoffman (1991) and the supporting theories of this study were the theory from Apple and Muysken (1987). The result of the analysis showed that there are ten (10) sentences of intra-sentential code-switching and three (3) sentences of inter-sentential code-switching. Some data found contained poetic and phatic function.
Sustaining Rasicm In Popular Literature The Girl With Louding Her Voice By Abi Dare’
Authors: Alfadlilah Muna
Published: October 2024

Popular fiction is part of popular literature that is very like and read by the society. The desire of the public to consume literary works is very related to tastes and what is viral in society at that time. Every that moves the public in the consumption of society is certainly driven by a belief, one of which is the belief in the issues that exist in society. One of the issues that exist in society is racism. Strong racism arises because of differences according to ideology in the western view. This study examines the analysis of sustaining racism with a postmodern approach in the novel The Girl with Louding Voice by Abi Dare'. Explaining that women cannot live freely and are not given the opportunity to run and continue their education. This article used postmodern approach with seeing the phenomenon about society to literature. The result of this study is that society still has several points of view regarding racism so that many consume this literary work. Fiction that is still hotly discussed by the public about the lives of black people. Keywords: Rasicm, postmodern, popular literature.
From Song to Loyalty: How the Anthem of Universitas Trunojoyo Madura Enhances Student Engagement and Strengthens Institutional Bonds
Authors: Saksono Suryo Tri
Published: October 2024

University anthems, as key elements in shaping the identity of higher education institutions, reflect the values and history of the university and enhance a sense of community. This study focuses on how the integration of traditional Madurese elements in the anthem of Universitas Trunojoyo Madura influences student identity and engagement. The knowledge gap lies in the actual influence of traditional music in enhancing student engagement and loyalty. A qualitative methodology was employed, involving in-depth interviews and lyrical content analysis of the anthem to uncover student perceptions. The primary findings suggest that the use of traditional Madurese music elements enhances student pride and engagement, strengthens institutional identity, and reinforces community bonds. The implications of these findings affirm the crucial role of arts and literature in facilitating social and communal engagement in academic settings, providing new insights for the development of educational strategies and university policies.
DETEKSI KEBOHONGAN BERDASARKAN FITUR-FITUR SUPRASEGMENTAL: PENDEKATAN LINGUISTIK FORENSIK
Authors: Santoso Budi
Published: October 2024

This research was conducted to detect lies based on suprasegmental features from phonetic studies using a forensic linguistic approach. This research uses a qualitative method by applying experimental phonetics described in narrative form. Data collection was obtained from the results of interrogation which were stored in the form of recordings (wav. file). The interrogation was carried out after the determination of the research sample as many as three students (two men and one woman) who became suspects. Data processing used Praat voice analyzer software version 6.3.09 to display the suprasegmental features of speech that indicated lies. Based on the data processing, it was found that rapid intonation changes from rise to fall, or vice versa indicated a person's level of tension in speaking, as well as the presence of pauses in a longer duration and high voice frequency in the initial position of speech characterizes that someone commits lying.
Technological Features of Filler Wire Melting for Arc Welding and Surfacing with the Introduction of SF6 into Protective Gas Atmosphere
Authors: Karatseyeu A. A. , Fiatsisava K. A. , Parshin S. G. , Karatseyeva A. A.
Published: October 2024

On the basis of the results of experimental studies the paper establishes important patterns of dependence of the frequency of short circuits of the arc gap and the coefficient of loss of electrode metal due to spatter from the voltage on the arc and the feed rate of the filler wire during welding and surfacing with the introduction of gaseous SF6 into the Ar + CO2 protective mixture. It is proposed to introduce fluorine-containing components of SF6 directly into the protective gas mixture of 82 % Ar + 18 % CO2 in quantities not exceeding 2 %. The technology makes it possible to reduce the amount of diffusion hydrogen in the deposited metal, which is an urgent task when welding high-strength steels and materials sensitive to hydrogen embrittlement. Previously, we resolved a number of issues related to the obstacle to increasing the concentration of S in the deposited metal, which made it possible to determine the most effective concentrations of SF6 in the protective gas environment, limited to 1.5 % by volume of the total composition (Ar + CO2) + SF6. At the same time, modification of the protective gas atmosphere with the halide compound SF6 has a significant effect on the melting characteristics of the electrode wire and temperature indicators in the arc combustion zone. This is due to the high ionization potential of fluorine as a product of the high-temperature dissociation reaction of SF6. The results obtained have made it possible to determine the most effective relationships between the values of the mode parameters, as well as to study the specifics of melting the filler wire in a protective atmosphere modified with SF6. Important regularities have been established that reveal the technological features of welding and surfacing with modification of the protective atmosphere with halide compounds.
G- Cyclicity And Somewhere Dense Orbit
Authors: Jamil Zeana Zaki
Published: October 2024

ليكن H فضاء هلبرت على حقل الاعداد العقدية قابل للفصل غير منته البعد وS شبه زمرة جدائية من تحتوي على 1. يقال للمؤثر الخطي T انه دوري من النمط G على  Sاذا وجد متجه غير صفري xÎH بحيث ان
{a Tn  x½aÎS, n ≥0} كثيفة في H.
بوردن وفيلدمان برهنا وجود مدار كثيف في مكان ما يؤدي الى فوق الدوارية. في هذا البحث اعطينا نتائج مماثلة في حالة دواري من النمط G.
W. James and S. Frank: Two Interpretations of Pascal’s Wager
Authors:   Moscow Pedagogical State University, Chernenko Oleg
Published: October 2024

Blaise Pascal is considered one of the most influential thinkers of his time, and his questions about the nature and position of man in the world remain relevant to this day. Pascal’s famous wager continues to be a subject of discussion among thinkers of various orientations. This article analyzes two interpretations of Pas­cal’s famous argument in defense of religious faith – those of W. James and S.L. Frank. By examining both thinkers’ interpretations of Pascal’s Wager, the article highlights the distinctive perspectives of W. James and S.L. Frank on the concept of religious experience. The basis for this comparison is the re­ception of W. James’s philosophical and religious ideas by the Russian philo­sopher. James’s ideas were relevant during the Russian religious renaissance of the early 20th century, receiving both positive reviews and criticism. The author of the article identifies similarities and differences in the two interpretations of Pascal’s Wager, which allows for a deeper understanding of the philosophical spirit of both W. James and S.L. Frank. It is emphasized that the views of the Ame­rican pragmatist and the ideological interpretation of the wager by the Russian philosopher share a particular approach to the concept of religious experience. Turning to the ideas of W. James and S.L. Frank provides a foundation for as­serting that, on the ground of the domestic intellectual tradition, both religious experience and religious philosophy are “integrated” into the philosophy of com­munication, transcending purely religious thought
The Concept of ki in the Theory of Japanese Martial Arts of the Tokugawa Era. A Study Based on the Treatise Tengu geijutsu ron (1729) by Issai Chozan
Authors:   Lomonosov Moscow State University, Institute of Asian and African Studies, Gorbylev Alexey
Published: October 2024

The concept of кi (Chinese Qi) – “pneuma”, “air”, “breath”, “spirit”, “energy”, “life force”, “matter”, etc. – is one of the fundamental and most specific cate­gories of Chinese and, more broadly, Far Eastern philosophical thought. In Japan, the assimilation of the кi category began with the penetration of Chinese reli­gious and philosophical thought. In the theory of martial arts (bujutsu) – the arts of swordsmanship, etc. – the category ki enters in the Tokugawa era (1603–1867) along with the establishment of Confucianism as the dominant current of social thought. In 1729, Issai Chozan (1659–1741) published the treatise Tengu geijutsu ron (“Discourses of tengu on the art [of swordsmanship]”), in which, for the first time in bujutsu literature, he not only systematically examined the functions of ki, but also gave practical instructions on managing ki with the help of breath­ing exercises and concentration practice, laying the foundation for the develop­ment of martial arts as one of the methods of “nurturing life” (Japanese yojo, Chinese yangsheng). The article systematizes Issai Chozan’s ideas about the es­sence and functions of the ki, and reveals the place of this concept in the peda­gogical technology of achieving mastery in martial art
Philosophical Thinking on the Way to Freedom
Authors:   Lomonosov Moscow State University, Kosilova Elena
Published: October 2024

The article considers one of the ways to achieve philosophical truth – the inner freedom of the subject. The doctrines of evolutionary epistemology and radical constructivism equate thinking with a means of adaptation. The best thinking is the one, thanks to which the organism survives and leaves maximum offspring. Freedom of thinking in such doctrines is absent, it is determined by the brain and its adaptive tasks. However, at a higher level of analyzing the human personality, one can speak of freedom. Heidegger establishes an inseparable connection be­tween freedom and truth: freedom is “letting beings be”. Only by letting this the cognizing subject can adequately cognize. This requires the renunciation of power, of mastery over the world, of its use as an instrument. Marion argues similarly in the doctrine of the saturated phenomenon. However, this kind of freedom can be called external. The notion of inner freedom is introduced. It is also inseparable from truth, and is now the truth of self-knowledge. Self-knowledge requires non-trivial approaches, as psychoanalysis has shown. The ar­ticle discusses the teaching of D. Winnicott on the true and false self and the theory of E. Ghent of “surrender”. The greatest obstacle to self-knowledge, according to Ghent and other theorists, are psychological defense barriers. They allow us to displace thoughts about ourselves that are unpleasant to us and undermine our self-confidence. In doing so, we alienate ourselves from our true Self. Ghent’s theory of “surrender” describes the breaking down of defense barriers and the in­ner liberation of the Self. Outwardly and inwardly free philosophical thinking is not the proof of a pre-known truth, but wandering (Heidegger). Genuine philo­sophical questioning does not know in advance where it will arrive, but on the way of wandering in a contemplative state it analyzes what is revealed to it
Understanding Time by K.F. von Weizsäcker
Authors:   Institute of Philosophy, Russian Academy of Sciences, Sevalnikov Andrey
Published: October 2024

The work is devoted to the problem of understanding of time by the German physi­cist and philosopher Karl Friedrich von Weizsäcker. In the book “The Structure of Physics”, he convincingly challenges the point of view of physicists, according to which time is an illusion, and attempts to build physics based on a key under­standing of time. The scientist considers three modes of time: past, present and fu­ture. The past is factual and can be confirmed by documents. The future is seen as open, connected with a “fan of possibilities”. The key issue is to reduce the three modes of time to one, based on the concept of facticity. Weizsäcker shows that this is logically possible. When working, he relies on the methodological technique of “movement in a circle”. The initial assumptions on which the reasoning is based are questioned, then new assumptions are considered, and a new picture is built based on them. Accepting the thesis about the factuality of the future, the question arises about the “documents of the future”. Weizsäcker’s answer is original – these are phenomena of predictions or prophecies. Realizing the controversy of such a statement for modern science, Weizsäcker builds a “phenomenology of prophe­cies”. The existence of such “documents of the future” is a fact for him, although he admits that he cannot explain them either from the point of view of physics or within the boundaries of his theory. Solving this problem, he comes to the con­clusion that there must be another mode of time, the nature of which cannot be ex­plained within the framework of modern science
THE EFFECTIVENESS OF STEM CELL THERAPY IN MYOCARDIAL INFARCTION REVIEWED FROM UREUM, CREATININE AND KIDNEY HISTOPATHOLOGY LEVELS
Authors: Rahmi Nur , Gunanti Gunanti , Noviana Deni , Harlina Eva
Published: October 2024

This study aims to study the effectiveness of single placental stem cell therapy or cardiomyocyte combination in pigs experiencing myocardial infarction in terms of urea, creatinine and kidney organ histopathology values. A total of 9 pigs were divided int o three groups: without therapy (K1), single placental stem cell therapy (K2), and cardiomyocyte coculture combination therapy (K3). All pigs underwent circumflex artery ligation of the proximal coronary artery branch to stimulate cardiac ischemia and therapy was given after myocardial infarction and ST-elevation were formed. The pigs were then treated for eight weeks, euthanized and necropsied for kidney organ removal. The re sults showed a significant decrease in urea and creatinine values (P0.05) in K2 and K3 as compared to K1. Histopathology results showed a decrease in glomerular atrophy values (K2: 10.26±0.93 and K3: 12.44±1.21), tubular necrosis (K2: 13.67±3.76 and K3: 17.23±0.55), and tubular dilation (K2: 16.36±1.26 and K3: 18.03±1.76) and these values were significantly different than those observed in K1. It was concluded that the administration of placental stem cell therapy or combined with cardiomyocyte coculture could reduce urea, creatinine values, and improve kidney tissue histopathologically.
THE EFFECTIVENESS OF VITAMIN C AND E ADDITION IN VARIOUS DILUENTS OF BRAHMAN CATTLE SPERMATOZOA AFTER FREEZING
Authors: Suharyati Sri , Hartono Madi , Siswanto Siswanto , Nur Wahid Agus , Rangga Saputra Hanip , Nilam Sari Fatma
Published: October 2024

This research aimed to determine the quality of Brahman cattle spermatozoa after freezing in various diluent ingredients (Egg Yolk Citrate, Egg Yolk Tris, Skim Milk) which added vitamin C and vitamin E. The research was carried out using 4 treatments with 3 different diluent ingredients, each of which was Vitamins C and E are added to each diluent ingredient at a dose adjusted to the type of diluent agent. The treatment given is P0: Diluent without Vitamin C and E; P1: Diluent + Vitamin C; P2: Diluent + Vitamin E; and P3: Diluent + Vitamin C and Vitamin E. Research data were analyzed using analysis of variance and followed by Duncan's test at the 5% and/or 1% level for different variables. The results showed that the addition of vitamin C and vitamin E had a significant effect (P0.05) on motility and viability in the egg yolk tris diluent and egg yolk citrate but had no significant effect (P0.05) in the skim milk diluent. The use of different diluents had no significant effect (P0.05) on motility, viability, and abnormalities. This research concludes that Vitamin C added to the diluent tris egg yolk, egg yolk citrate, and skim milk showed higher average motility, percentage of live spermatozoa, and abnormalities of post-freezing Brahman cow spermatozoa.
PRODUCTION PERFORMANCE OF QUAIL (Coturnix-coturnix japonica) AND IDENTIFICATION OF IgY CONCENTRATION IN BLOOD SERUM AND YOLK
Authors: Tarigan Indri Nur Krisna , Afnan Rudi , Murtini Sri , Ulupi Niken
Published: October 2024

This research was conducted to provide information on the production performance of quail parent stock and its offspring with various IgY concentrations. A total of 42 female quail parents stock aged five weeks old were used in this study. Five quails were categorized as medium IgY group with concentrations of 431.12-531.87 µg/mL and 37 quails were categorized as low IgY group with concentration of 251.87-384.68 µg/mL. The variables observed were the production performance such as initial body weight, feed intake, final body weight, body weight gain, number of eggs, egg mass, egg weight, egg laying intensity, feed conversion, morbidity, and mortality rate and IgY concentration of the yolk of the offsprings. Production performance of female quail with different concentrations of IgY was not significantly different (P0.05). IgY concentration of offsprings in egg yolk was also not significantly different (P0.05) in both groups. The results showed that female quails parent stock with low blood IgY showed better production. Meanwhile, female quail parents’ stock with moderate blood IgY concentrations produced offspring with high-maternal IgY concentrations in yolk.
AI Literacy and Teaching Self-Efficacy Enhancement in Future Pre-service Teachers: A Case Study of Education Office Camp Implementation
Authors: Kim Mi-Young , Nam Jung-Mi
Published: October 2024

Objective: This study analyzes the effectiveness of the Education Office's high school Winter/Summer School camp during school vacations for enhancing the artificial intelligence (AI) digital competences of high school students aspiring to become future teachers, and students' satisfaction.
Methods: To measure the effects and satisfaction, we conducted pre- and post-course surveys using Google Forms to assess students' perception of AI, AI literacy, and teaching efficacy. We supplemented these quantitative data with qualitative data by utilizing participants' learning logs and conducting interviews. Finally, we fostered interaction among the participants during the learning process through Naver Band, and observed the outputs and learning process through activities such as creating teaching and learning content using AI and digital tools.
Results: We found high satisfaction levels, and significant positive effects on students' perception of AI, AI literacy, and teaching efficacy. Clearly, the camp courses helped participating students develop AI literacy, enhance teaching efficacy, and build their competencies as future teachers.
Conclusions: The "AI and Digital Competency Education Practicum for Future Teachers" conducted in the Winter/Summer School can enhance participants' AI literacy, teaching efficacy, and overall learning satisfaction. This has important educational implications for future teacher training.
Chemical composition, insecticidal and acetylcholinesterase inhibitory activities against Parlatoria blanchardi Targ of essential oils from Deverra scoparia Coss. & Dur. dried with different methods
Authors: HAMMOUDI Roukia , CHEBROUK Farid , Benameur-Saggou Hayet , Belkhalfa Hakim , Mahammed Mahfoud Hadj , Saher Liza , Abou-mustapha Mohamed , Haffas Maamar
Published: October 2024

Deverra scoparia Coss. & Dur. (Apiaceae) from Algerian Sahara was dried by two methods, conventional (sun, open air) and microwave at different powers (264, 400, 800 W). The essential oils (EOs) were obtained from the different samples by hydrodistillation and analyzed by gas chromatography coupled with mass spectrometry (GC-MS). 32 constituents were identified and the oils compositions were found to be dominated by Myristicin (43.44–69.73%), D-Limonene (6.61–12.57%), Dillapiole (0.74–10.87%), α-Phellandrene (0.47–8.16%) and α-Pinene (4.36–8.10%) as the main constituents. Then, the EOs were evaluated for their insecticide activity against the white cochineal of the date palm Parlatoria blanchardi Targ (Hemiptera- Diaspididae) by the spraying method, thus the inhibition activity of its acetylcholinesterase (AChE). The obtained results showed an important efficacy of the EOs against this insect with lethal doses (LD50) ranged from 2.32 to 6.12 µL/mL. Moreover, the study of the inhibition of AChE showed a strong inhibitory effect against this enzyme, with an EC50 value of 0.002 µL/mL. These results suggest that this plant might be efficient as potential alternative control agents for Parlatoria blanchardi Targ.
Plastic sex-trait modulation by differential gene expression according to social environment in male red deer
Authors: Broggini Camilla , Abril Nieves , Membrillo Alberto , Peña Eva de la , Carranza Juan
Published: October 2024

Mate competition encourages individuals to modulate characters involved in mating success. Adult Iberian red deer (Cervus elaphus hispanicus) males show a dark ventral patch (DVP) that plays a central role in mating rivalry, whose size and chemical compounds varied according to the level of male-male competition within the population. In the pigmentation of the DVP appears, after urinary excretion, a molecule called DOPEG originating from the metabolism of norepinephrine, leading us to investigate whether differential expression mechanisms of key genes (DBH and TH) encoding enzymes catalyzing the process can be sensitive to different competitive population situations and responsible for the plastic development of the DVP in red deer. We found that social environment with higher intrasexual competition, where male invest more in sexual traits, was associated with increased levels of DBH and TH transcripts, while Dopamine showed reversed values. We found alternative splicing for the TH gene, although differences between social environments appeared just related to expression levels. Our results support the internal cause of trait modulation based on differential gene expression in relation to the conditions of intrasexual competition in social environment. We propose the quantification of DBH transcripts as a molecular biomarker of male red deer reproductive activity.
Longitudinal changes in skeletal muscle and adipose tissue during surgical treatment of oesophagogastric cancer: a prospective study.
Authors: Murnane Lisa , Forsyth Adrienne , Koukounaras Jim , Shaw Kalai , Paul Eldho , Brown Wendy , Tierney Audrey , Burton Paul
Published: October 2024

Background
Low muscle mass, myosteatosis, and excess adiposity are associated with adverse outcomes after oesophagogastric (OG) cancer surgery. There is limited prospective data to evaluate body composition throughout treatment. We aimed to measure longitudinal changes in skeletal muscle and adipose tissue and describe variations according to baseline BMI.
Methods
This prospective longitudinal study included patients having OG cancer surgery at Alfred Health, Melbourne, Australia. CT images and bioimpedance spectroscopy (BIS) were used to assess body composition at multiple time points up to 12 months postoperatively. Low skeletal muscle, myosteatosis and visceral obesity were defined using published thresholds. BMI groups were defined as ≥ 30kg/m2 (obese) and < 30kg/m2 (non-obese).
Results
There were 50 patients. During neoadjuvant treatment, CT-muscle declined (152.7 vs 142.4cm2, p<0.001) and adipose tissue was stable. Postoperatively, total adipose tissue reduced (357.7 vs 224.4cm2, p<0.001), but muscle did not (142.4 vs 133.6cm2, p=0.064). Low CT-muscle prevalence increased during neoadjuvant treatment (diagnosis 33%, restaging 49%, p=0.02) but not at 12 months (54%, p=0.21). Visceral obesity was common and stable between diagnosis and restaging (58% vs 54%, p=1.00) with a marked reduction at 12 months (19%, p<0.001). BIS-muscle declined rapidly early after surgery and did not recover. The proportion of muscle and adipose tissue loss between BMI groups was comparable.
Conclusion
Weight loss during OG cancer treatment is significant. Skeletal muscle loss occurs during neoadjuvant treatment, while adipose tissue loss is predominant postoperatively. Anticipated changes in body composition should be considered throughout treatment, focusing on early muscle loss.
Machine Learning Analysis of Ocular Blood Flow for Estimating Vascular Age
Authors: Naito Atsuhiko , Magi Shigeyuki , Maruyama Takahiro , Takagi Seiji , Hori Yuichi
Published: October 2024

The process of aging varies among individuals. Some age faster than their true age while others remain more youthful than their chronological age. In this study, we developed machine learning models to predict chronological age using time-series blood flow images of ocular vessels captured through laser speckle flowgraphy (LSFG). The inclusion of features generated through automated feature engineering improved the model’s accuracy over predefined features. Elevated blood pressure and blood glucose levels were more prevalent in subjects whose model-predicted age was older than their true age, highlighting the importance of these factors in vascular aging. We further investigated features explaining the divergence between model-predicted and true ages and identified features that could be useful for detecting whose biological age exceeds their chronological age. These results demonstrate the potential of LSFG-based machine learning models to predict vascular aging and identify individuals with increased cardiovascular risk in apparently healthy populations.
Using the Implementation Research Logic Model to Examine High-Intensity Resistance Rehabilitation Implementation in Skilled Nursing Facilities: A Mixed Methods Multi-Site Case Study
Authors: Hinrichs-Kinney Lauren , Derlein Danielle , Pontiff Mattie E , Malone Daniel , Holtrop Jodi Summers , Stevens-Lapsley Jennifer E
Published: October 2024

Background
Implementing evidence-based rehabilitation in skilled nursing facilities (SNFs) is essential for enhancing physical function outcomes and mitigating risk of adverse events. Best implementation approaches in this complex setting are unknown. This study uses the Implementation Research Logic Model (IRLM) to examine the implementation of high-intensity resistance rehabilitation (HIR) in SNFs, aiming to elucidate contextual factors and processes that could enhance future HIR implementation endeavors.
Methods
We conducted a mixed-methods multi-site case study (n = 8 sites) to examine implementation. A standardized implementation strategy was employed, allowing sites to tailor their approaches. Use of HIR was measured using the Provider Report of Sustainment Scale (PRESS). Contextual factors were identified using the Practical Robust Implementation and Sustainability Model (PRISM) through study-specific questionnaires and validated measures (Inner Setting Scale, Provider Perspective of Team Effectiveness, Evidence Based Practice Attitudes Scale, Perceived Characteristics of Intervention Scale, Self-Defined Burnout Measure, and Utrecht Engagement Scale), and analyzed descriptively. Interviews and focus groups with leadership and clinicians revealed contextual factors and processes influencing implementation. Heat maps visualized site trends, while an Implementation Research Logic Model (IRLM) proposed provisional implementation processes.
Results
PRESS scores ranged from 3.75 (0.17) to 2.33 (0.67) indicating all sites implemented HIR to at least a “moderate extent”. Higher-implementing sites demonstrated full-team ability to accommodate HIR to diverse patients. Differentiating factors between higher and lower implementing sites included clinician perspectives, site infrastructure, and satisfaction with leadership. Higher-implementing sites employed a higher volume of site-initiated implementation strategies, notably having a champion and consumer engagement. Processes that appeared to contribute to higher implementation extent included: 1) overcoming inertia of current practice through salience, 2) overcoming clinician concerns of patient compatibility through affirmative experiences, 3) addressing clinician perspective of complexity with session planning, and 4) optimizing patient rehabilitation mindset through encouraging environments.
Conclusion
Improving physical function in older adults necessitates adoption of evidence-based rehabilitation like HIR. Implementation strategies that target infrastructure, including leadership support and communication channels, inertia of current practice, and clinician perspectives of HIR complexity and patient compatibility may facilitate implementation. Identifying a champion and providing guidance for effective patient engagement appear to be key.
Treatment of phase II empyema with intrapleural alteplase vs surgical debridement in children: A retrospective cohort study
Authors: Cuellar Maria Paula Vargas , Reyes Isabel Cristina Cañon , Ramirez Lilian , Romero Maria De Los Angeles , Ucros Carmen , Rueda Sergio , Mogollon German
Published: October 2024

Purpose
Describe a treatment protocol with intrapleural alteplase for phase II empyema in children and compare its efficacy and development of complications with surgical debridement.
Methods
Retrospective cohort design of children with phase II empyema treated with surgical debridement or alteplase through thoracostomy. Clinical outcomes and postoperative complications were analyzed. Efficacy was evaluated by resolution of empyema and need for re- intervention.
Results
38 patients were analyzed. Intrapleural alteplase presented less days of hospitalization (21.79 vs. 22.11 days), less blood transfusion requirement (36.84% vs. 42.11%) and less need (9 vs. 13 patients) and days of invasive mechanical ventilation (4.33 vs. 5.92 days), with no statistical difference (p = 0.68; p = 0.74; p = 0.68 respectively). Treatment failure was present in 4/19 patients treated with alteplase requiring further intervention compared to 6/19 patients treated with surgical debridement.
Conclusions
Intrapleural alteplase is as effective as surgical debridement for the treatment of phase II empyema for disease resolution and need for re-intervention. This study shows its safety and optimal clinical outcomes, minimal adverse events, less morbidity and clear clinical advantages due to its less invasive nature.
Prostate-Specific Antigen (PSA) and Its Association with Cardiovascular Disease Risk in US Men: A Population-Based Study
Authors: Chen Zhi-huang , Liu Yi-jiang , Li Rui , Wang Zhan , Chen Jia-lin , Li Li , Xiao Di , Jiang Shu-yan , Xu Lin-xi , Chen Xin , Zhuang Jia-wei , Xu Jia-cheng , Shan Zhong-gui
Published: October 2024

Background
This study aims to examine the associations of total PSA (tPSA), free PSA (fPSA), and PSA ratio with CVD risk in the adult male population of the United States.
Methods
In this study, we utilized data from the National Health and Nutrition Examination Survey (NHANES) database with cardiovascular condition,PSA levels and confounding factor information spanning 2001 to 2010. We tabulated the selected data to compare the baseline characteristics of participants.Using a multivariate logistic regression model, we calculated odds ratios (OR) and 95% confidence intervals (95% CI) to assess the potential correlation between total PSA (tPSA), free PSA (fPSA), and the PSA ratio with the odds of CVD and revealed that fPSA was the most significantly related. Subsequently, we divided fPSA into quartiles to further explore the differences in risk association among the different intervals. Additionally we applied forest plots to display the effects of covariates in this risk relation. Two-sided p-tests derived from Wald tests were applied to verify the significance of the results.
Results
Higher fPSA levels were significantly associated with an elevated risk of CVD in each model(Model1: OR:1.90;95%CI: 1.48–2.46; P < 0.001 ;Model2: OR:1.89;95%CI: 1.47–2.42; P < 0.001 ;Model3:OR:1.71;95%CI: 1.33–2.20; P < 0.001). The multivariable OR for the highest versus lowest quartile of fPSA after fully adjusted was 2.55 (95% CI: 1.98–3.29; P-trend < 0.001). Similar but weaker associations were observed for tPSA and PSA ratio. In the fully adjusted model of tPSA, the OR was 1.08 (95% CI: 1.03–1.12; P < 0.001), and for PSA ratio, the OR was 1.01 (95% CI: 1.00-1.01; P = 0.11).
Conclusions
Our study suggests that elevated fPSA levels may be associated with a higher prevalence of CVD. This analysis offers a novel perspective on the complex relationship between PSA and CVD. Further research is warranted to elucidate the potential mechanisms underlying this association in this filed.
Combating Deepfakes Using an Integrated Framework forAudio and Video Deepfake Detection
Authors: Sharma Vishal Kumar , Singh Shailendra Narayan , Caudron Quentin
Published: October 2024

The creation and accessibility of synthetic audio-visual media which is commonly known as deepfakes has been into an alarming situation with the rapid advancement of generative AI techniques. This media is fabricated or sometimes manipulated and it can serve threats to individuals’ privacy, security and integrity of information. This situation makes it crucial to develop robust and reliable deepfake detection methods to mitigate these risks. We present a multimodal approach to deepfake detection leveraging both audio and visual signals. By harnessing the power of deep learning, our proposed framework extracts discriminative audio and visual features which are then fused to classify the synthetic media effectively. For audio analysis, we employ mel-spectrogram representations and convolutional neural networks (CNNs) to capture spectral patterns indicative of deepfakes. On the front of video, we utilize facial landmark detection, alignment, and deep CNNs to model facial cues and inconsistencies associated with deepfakes. The fusion of these audio and video modalities enables our model to capitalize on complementary information, enhancing its ability to detect deepfakes accurately. Extensive experiments on benchmark datasets, including DeepFakeTIMIT and DFDC, demonstrate the efficacy of our approach, achieving a precision of 0.78, an accuracy of 0.93, and an F1 score of 0.82, outperforming several state-of-the-art monomodal methods. Our findings underscore the importance of multimodal analysis for robust deepfake detection and pave the way for developing more sophisticated techniques to safeguard media authenticity in an increasingly synthetic world.