bluuebunny/crossref_metadata_2025 huggingface dataset:
Early intervention in viper bites: a potential strategy to mitigate acute kidney injury and its long-term consequences
Authors: Mushtaq Rabeea , Ramlah Naz  , Mehreen Fatima
Published: October 2024

Dear Editor,
By this letter we intend to highlight the close association between snake bites and acute kidney injury, as the causative snakes are common natives of Tropical regions and a common cause of death because of being poorly managed.
Snake bites are a significant cause of acute kidney injury in tropical regions, particularly in Eastern Pakistan, where Russell's viper, a common cause, is prevalent. The farmlands of Sindh and Balochistan are predisposed to snake bites due to their favorable weather and vast fields. A 2020 study found 454 snakebite cases in Southern Sindh, with 6 deaths. The most common mechanisms are venom-mediated consumption coagulopathy (VMCC) and endothelial damage, leading to systemic bleeding diathesis and decreased perfusion of end organs. Long-term effects of snake bites include worsening renal conditions and progression towards end-stage renal disease.
Eastern Pakistan commonly harbors Russell’s viper- a frequent cause of snakebite-associated mortality, which belongs to the Viperidae family and is famously known to produce vasculotoxic venom. (1) The farmlands of Sindh and Balochistan are predisposed to snake bites as the weather of these regions and the vast fields allow the vipers to flourish and thrive well. A study conducted in 2020, representing the population of Southern Sindh, demonstrated a total of 454 cases of snakebite in a span of 1 year, out of which 6 victims died. (2) Since the prevalence of vipers is common in the district of Sindh, the deaths could be attributable to the hemorrhagic manifestations of vipers' bites.
The most significant mechanisms underlying viper bite presentations are venom-mediated consumption coagulopathy (VMCC) and endothelial damage resulting in systemic bleeding diathesis, which together contribute to decreased perfusion of end organs like the heart, kidneys, brain, or gastrointestinal system. (3) VMCC is a major contributor to acute kidney injury (AKI), a common outcome of vasculotoxic snake bites, along with enzymatic dissolution of the glomerular basement membrane (BM) by the venom metalloproteinases. (4) The hemorrhagic deterioration of the vessels leads to ischemic nephropathy, and the impaired BM allows proteinuria, hemoglobinuria, and increased creatinine, often predisposing the victim to timely dialysis. A study concluded that individuals with co-morbidities are more susceptible to developing long-term effects of snake bites like worsening renal conditions such as new-onset hypertension, dialysis dependence, and end-stage renal disease. (5)
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Unforeseen severity in a case of neonatal cow milk protein allergy: a case report
Authors: Imran Alizeh , Lakdawala Fatima Mustafa , Khan Shahzaib
Published: October 2024

Cow milk protein allergy (CMPA) is one of the most common childhood allergies that manifests with a range of digestive symptoms and skin reactions, which usually resolve with age. In this report, we present the case of a one-month-old male who presented with a rare and severe manifestation of neonatal CMPA. The neonate underwent numerous hospital admissions due to a presentation that closely mimicked symptoms of a metabolic disorder and sepsis. Our primary objective is to highlight the significance of systematically considering or excluding a CMPA diagnosis, irrespective of the severity of presentation. This proactive approach may potentially reduce future complications among the affected paediatric population, thereby preventing prolonged hospitalisation and the associated disease burden, as seen in this case.
Keywords: Cow milk protein allergy, Metabolic acidosis, Amino-acid based infant formula, Neonatal food allergy, CMPA.
Frequency and pattern of adult congenital heart disease in a tertiary care cardiac hospital: reasons associated with delayed diagnosis
Authors: Ahsan Aliya Kemal , Sangi Rumana , Shaikh Abdul Sattar , Mohammad Mohsin  , Saba Mumtaz
Published: October 2024

Objective: To determine the distribution pattern and possible reasons of delayed diagnosis of congenital heart disease in adult population.
Method: The analytical, cross-sectional study was conducted at the Department of Paediatric Cardiology, National Institute of Cardiovascular Diseases, Karachi, from July to December 2021, and comprised patients of either gender aged 18 years and above with congenital heart disease confirmed by echocardiographic examination. Age, gender, weight, height, provincial affiliation, marital status, number of children, if any, duration of disease and New York Heart Association classification were noted on a predesigned proforma. Patterns of congenital heart disease types and reasons behind delayed diagnosis, if noted, were recorded. Data was analysed using SPSS 26.
Results: Of the 129 patients, 68(52.7%) were males. The overall mean age was 25.8±9.8 years. Mean age at the time of diagnosis was 12.4±14.8 years. There were 91(70.5%) cases with delayed diagnosis. There was no significant gender difference with respect to delayed diagnosis (p>0.05). Delayed referral 39(42.9%), delayed consultation 22(24.2%), delayed diagnosis by the doctor 21(23.1%), and social factors 9(9.9%) were the most frequent reasons behind delayed diagnosis. Ventricular septal defect was the most frequently defect 38(29.5%), followed by tetralogy of fallot 32(24.8%). Right ventricular dysfunction was the most common complication of delayed diagnosis 35(27.1%).
Conclusion: Delayed diagnosis of congenital heart disease was reported in over two-thirds of the cases, with ventricular septal defect being the most frequent type of defect, and delayed referral being the most common reason.
Key Words: Congenital heart disease, Diagnosis, Echocardiography, Tetralogy of fallot, Ventricular septal defect.
A cidade e o cidadão: por uma abordagem político-territorial do conceito de cidadania a partir de uma perspectiva emancipatória
Authors: Raique Lucas de Jesus Correia  , Waldemar Almeida de Oliveira Filho  , José Euclimar Xavier de Menezes
Published: October 2024

O presente artigo propõe uma análise do conceito de cidadania a partir de uma ancoragem territorial, que confere relevo a uma perspectiva articuladora entre Direito e Geografia. Mediante pesquisa de viés exploratório, procura deslocar a discussão da cidadania como categoria jurídico-normativa para concebê-la dentro de um quadro político mais amplo, alicerçado nas lutas e movimentos sociais de resistência de base territorial. O percurso começa localizando as formas de apreensão da cidadania em diferentes períodos da história ocidental, analisando as mudanças, continuidades e contradições que foram se estabelecendo ao longo do tempo. Após isso, discute-se a relação entre cidadania e território, invocando o componente territorial como conteúdo materializador do próprio exercício da cidadania. Finalmente, busca-se atrelar o conceito de cidadania à noção de resistência territorial, partindo sobretudo de uma visão crítica do poder constituinte dos Direitos Humanos. Com isso, conclui-se atestando a importância dos movimentos de insurgência e da dinâmica territorial nos processos de efetivação dos direitos dos cidadãos e emancipação do homem.
Implementasi Strategi Komunikasi Organisasi dalam Meningkatkan Motivasi Kerja: Studi Kasus PT Pallawa Sejahtera Mandiri di Kab. Mamuju
Authors: Setiawan Muhammad Aras , Ferdiansyah Rahmat , Sukmarini Andi Vita
Published: October 2024

This study aims to determine the Implementation of Organisational Communication in Improving Work Motivation at PT Pallawa Sejahtera Mandiri in Mamuju Regency and maintain the effectiveness of organisational communication in improving employee work motivation at PT Pallawa Sejahtera Mandiri.To fulfil these objectives, qualitative research was conducted at PT Pallawa Sejahtera Mandiri in Mamuju Regency, located at Jl. Lingkar Jalur Dua Airport, Kel Sinyonyoi, Kec Kalukku, Kab Mamuju. Research data were collected through observation and in-depth interviews. The data findings were then analysed, in order to achieve the desired results. The results of this study are to determine the Implementation of Organisational Communication in Improving Work Motivation at PT Pallawa Sejahtera Mandiri in Mamuju Regency in this study, PT Pallawa Sejahtera Mandiri includes various factors both internal and external, such as providing salaries/incentives, appreciation for performance, opportunities to take part in education and training, a comfortable work environment, and adequate office facilities. In increasing employee motivation in the office, it is determined by several things, including openness in communication, good human resource management, solid cooperation with all members of the organisation, and a clear understanding of the duties and functions of each employee in their field.
Penilaian Kepuasaan User dalam Menggunakan APlikasi SIM ASN Menggunakan Metode Website Quality
Authors: Kasuma Hidayatul Rahman , Huda Baenil , Hilabi Shofa Sofiah
Published: October 2024

Implementation of the State Civil Apparatus Management Information System (SIM ASN) is a must. The ASN SIM is not only an administrative tool, but is a digital ecosystem that integrates all personnel application services. The problem that occurs in the ASN SIM application is that users find it difficult to complete the complete history requested by the ASN SIM in the personnel database to update employee data history. The aim of this study is to assess the impact of three factors on user satisfaction: application quality, user-friendliness, and interaction quality. The evaluation process is based on the Website Quality technique, which takes into account multiple aspects of website quality, such as as information content, security, usability, speed, and interface design. Respondents in this study were frequent users of the ASN SIM Application. Questionnaires were used to gather information about user opinions and experiences with the quality of the program. To characterize the degree of user satisfaction and the variables influencing it, data analysis was carried out using both statistical and qualitative methodologies. In order to enhance the user experience and efficacy of using the ASN SIM Application in the everyday work environment, it is intended that the research findings will offer comprehensive insight into the areas that require further development. This study adds to the body of knowledge about user satisfaction evaluation in the context of government apps and may serve as a model for future research on the subject.
Perancangan Kebijakan Persediaan e-Commerce dengan Pertimbangan Permintaan Probabilistik dan Performance Score
Authors: Pujarani Amanda Sekar , Pambudi Hardian Kokoh , Setyawan Erlangga Bayu
Published: October 2024

Julis, a local company focused on the production and sale of perfumes through e-commerce platforms, is one of the SMEs facing such challenges. Julis has encountered difficulties in managing its product inventory, leading to high inventory costs and low customer order fulfillment rates (fill rate). These issues risk hindering the company's growth and diminishing consumer trust. This research aims to design optimal inventory policies for Julis by considering probabilistic demand and the company's performance score. This performance score is a measure of performance that integrates two key criteria: profit, calculated based on total inventory costs, and fill rate. With the right inventory policies, Julis is expected to improve inventory efficiency, reduce costs—particularly ensuring inventory costs meet the target of less than 40% of the company's total revenue or income—and achieve a minimum fill rate target of 95%, which is considered crucial for maintaining customer satisfaction and supporting business growth.The approach used in this research is an inventory optimization model that combines probabilistic methods in determining Order Quantity (Q) and Reorder Point (ROP). This design aims to address demand uncertainty, which often poses a major challenge in inventory management within the e-commerce sector. Additionally, this research introduces the integration of inventory classification based on performance score, enabling the company to prioritize certain products based on relevant performance criteria. As a result, each product category can be managed more efficiently and strategically according to business priorities. The results of this research indicate that the implementation of the designed inventory policies can significantly improve Julis' performance score. Specifically, in terms of cost efficiency, these policies can reduce inventory costs and increasing the fill rate, which directly positively impacts the company's profitability. Furthermore, the integration of inventory classification based on performance score has also proven effective in helping Julis identify the most critical products to prioritize in its inventory management.
Kajian Struktur Rangka Batang Jembatan Wailola Besar Kabupaten Seram Bagian Timur
Authors: Laipeny Fredrik Hendrik , Lewakabessy Godfried , Roberth Herry Henry
Published: October 2024

The Wailola Besar Bridge, which is located in Bula District, East Seram Regency, has a Warren truss type frame structure. However, unlike the truss used on other bridges, the truss on the Wailola Besar bridge has a larger size than the others. Because the span of the Wailola Besar bridge is 80 m, while the span of other bridges using the Warren truss type is a maximum of 60 m. The larger size than the other trusses makes the Wailola Besar bridge have a different truss from other trusses. The length of each horizontal bar is 6.65 m, while the maximum length for other bridges is 5 m. Then the purpose of this study is to determine whether the truss structure of the Wailola Besar bridge is capable of carrying the loads acting on the bridge, the method used is with the help of the SAP-2000 program to determine the truss forces then controlled with allowable voltage. In order to know whether the structure is able to withstand the forces acting. From the results of calculations with the help of SAP-2000 the rod forces acting on the largest truss structure are 11066.881 KN at constant loading and 12222.547 KN at temporary loading and the stress that occurs is 1742.82 Kg/〖cm〗^2. at constant loading and 1924.81 Kg/〖cm〗^2. The stress that occurs in the truss does not exceed the allowable stress.
Penyelesaian Kredit Macet dengan Jaminan Hak Tanggungan pada PT Bank Perekonomian Rakyat Pulau Punjung
Authors: Irawan Fira , Dilova Gisha , Wulandari Ratih Agustin
Published: October 2024

Providing credit does not always run smoothly, there are some loans that are bad because debtors do not carry out their obligations properly. If bad credit is not handled properly, it will have a bad impact on PT BPR Pulau Punjung because it will disrupt cash flow in and out. This research aims to find out: (1) What is the process of resolving bad credit with mortgage guarantees carried out by BPR Pulau Punjung? (2) What are the obstacles and constraints faced by BPR Pulau Punjung in resolving bad credit with collateral? (3) What efforts have been made by BPR Pulau Punjung to resolve the problems or obstacles that occur in bad credit with mortgage guarantees? This research method is empirical and includes descriptive research. The data source was obtained from interviews. The data collection techniques were literature study and field study. The results of this research are (1) The resolution of bad credit at PT BPR Pulau Punjung was carried out very well by making various efforts to save credit and in accordance with banking procedures. (2) constraints and obstacles faced by PT. Punjung Island BPR in resolving bad credit with mortgage guarantees is difficult to meet customers, bad customer character, economic factors, the credit given is not fully used for business, the debtor is not open to creditors, the debtor is negligent in the agreement, the condition of the debtor's family is not conducive. . (3) Efforts made by PT. Punjung Island BPR in resolving the problems and obstacles that occur in bad credit with collateral rights is applying the 5C 7P and 3R principles, and BPR proposes various efforts for bad credit which can still be saved by finding out the factors causing the bad credit by re-surveying and considering returned a request to save the bad credit. In conclusion, before executing the PT guarantee. BPR has made various efforts to save bad credit so that the debtor's credibility does not decline.
Proses Peradilan terhadap Pelaku Pengulangan Tindak Pidana Pencurian Ringan di Pengadilan Negeri Pulau Punjung: Studi Kasus Putusan Nomor: 8/Pid.C/2020/PN Plj
Authors: Priyanti Dita Anisya , Ikhwan Muhammad , Badri Ainul
Published: October 2024

The judicial process for perpetrators of repeat crimes of light theft should be processed using a regular examination or short examination, while at the Pulau Punjung District Court, cases of repeat crimes of light theft are processed using a speedy examination. The aim of writing this thesis is to understand the judicial process regarding the examination of perpetrators of repeat crimes of petty theft at the Pulau Punjung District Court, as well as to determine the Judge's obstacles in deciding the speedy trial process in case Number: 8/Pid.C/2020/PN Plj at the District Court Pulau Punjung. This legal research is empirical juridical research, namely research that uses field object data or is based on actual conditions. The results of writing this thesis show that: the judicial process for examining perpetrators of repeat crimes of petty theft at the Pulau Punjung District Court has not been effective, especially in case Number: 8/Pid.C/2020/PN Plj which is still being processed using a quick examination process, where the process Rapid examinations can only be carried out in cases of minor criminal offenses which are not repetitions of criminal acts (recidivism), the examination process for repetitions of minor criminal acts should be carried out using ordinary and short examination procedures. The judge's obstacles in deciding the speedy examination process in this case were the lack of accuracy in handing over the case files at the time of registration where one of the defendants was a repeat criminal, as well as the lack of communication and coordination between law enforcement agencies, namely investigators and prosecutors.
Pelayanan BPJS Peserta pada Jaminan Kesehatan di BPJS Kesehatan Kantor Padang Lawas Utara
Authors: Siregar Jumriani , Daulay Aqwa Naser
Published: October 2024

Quality health services are a right for every individual, including participants of the Health Social Security Administering Agency (BPJS). This study aims to analyze the services provided to BPJS Health participants in the North Padang Lawas area, with a focus on North Padang Lawas Health BPJS. The research method used is a descriptive approach with qualitative methods, direct observation, interviews with participants and officers, as well as analysis of secondary data related to service performance. The research results show that although BPJS Health has provided wider access to health services for the community, there are several challenges faced by participants in the North Padang Lawas area. Some of these are limited health facilities, especially in rural areas, long waiting times to receive services, and sometimes inadequate availability of medicines. The quality of service is also a major concern, where there are complaints regarding the attitude and responsiveness of officers and the availability of adequate medical personnel. In this context, increasing training for officers and improving health infrastructure in this region are very necessary to improve services to BPJS Health participants. This research contributes to the understanding of the quality of health services in the North Padang Lawas area, as well as providing a basis for BPJS Health and local governments to make necessary improvements to increase the quality and accessibility of health services for the community.
Eksplorasi Potensi Tanaman Lokal dan Pengaruh Formula Mordant sebagai Upaya Diversifikasi Motif Ecoprint
Authors: Mudjiati Mudjiati , Suryani Leny
Published: October 2024

This research explores the potential of local plants as materials in ecoprint techniques to create motif differentiation in fashion products. The study also aims to discover the optimal formula in the mordanting process. This research employs a practice-based research method to explore the potential of local plants as ecoprint materials and analyze the mordant formula for motif differentiation. The results come from the use of various types of leaves in ecoprint techniques to produce unique patterns and colors on fabric. Each leaf, such as guava, teak, mahogany, henna, and acacia, imparts different color characteristics and patterns. The formulation of the mordant solution and the technique of soaking the fabric have been shown to affect the ecoprint results, with alum mordant yielding darker and more defined colors, while potassium aluminum sulfate produces lighter colors.
Potensi Rempah-Rempah sebagai Bahan Pembuatan Minyak Balur
Authors: Purba Intan Sabila Putri , Rezky Deswita Ina , Samio Samio
Published: October 2024

As the villagers of Bandar Kuala become more knowledgeable about healthy lifestyles, the need for locally available herbal medicines with health benefits is bound to increase. Some of the sources of ingredients from spices and plants that are easily accessible to Bandar Kuala villagers and have various health benefits are turmeric, cardamom, bay leaves, soursop leaves, candlenut, sambiloto, frangipani flowers, kenanga flowers, anise, areca flowers, kencur, coconut oil, coriander, nutmeg, cloves, lempuyang wangi, temu mango, temu kunci. Phytochemicals from these plants are known to prevent or cure various diseases such as high blood pressure, cancer, diabetes, flu, cough, sore throat, pain and others. Cultivation of traditional medicinal plants in the garden on a large scale can be of economic value to the community, thus potentially improving the welfare of the villagers, and it is important to provide health education on the use of spices that already exist in an environment that is easily accessible to the residents of Bandar Kuala village.
Pola Implementasi Pelatihan Batik Cap Interaktif Motif Khas Pacitan untuk Anak Usia Sekolah Dasar
Authors: Ratnawati Ike , Prasetyo Abdul Rahman , Iriaji Iriaji , Wardhana Mitra Istiar , Aruna Alby , Surya Eka Putri , Marcelliantika Adinda
Published: October 2024

The implementation pattern of interactive stamp batik training with typical motifs of Pacitan Regency for elementary school children is designed based on adaptive learning and digital technopreneurship. The purpose of this training is to introduce batik skills from an early age and equip children with technological and entrepreneurial skills. Using a qualitative descriptive approach, data was collected through observation, interviews, and document analysis. The results showed a significant increase in children's understanding and skills in making batik stamps, as well as a greater appreciation of local cultural heritage. Training also contributes to the development of technology-based entrepreneurial skills. Challenges related to limited access to technology and training materials have been successfully overcome with an adaptive and collaborative approach.
Effect of Traditional Textile Techniques on Modern Fashion Design in Nigeria
Authors: Ibrahim Suleiman
Published: October 2024

Purpose: The aim of the study was to analyze the effect of traditional textile techniques on modern fashion design in Nigeria.
Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.
Findings: Traditional textile techniques in Nigeria, such as adire (tie-dye), akwete weaving, and aso-oke fabric, have significantly influenced modern fashion design. These indigenous methods, known for their intricate patterns and vibrant colors, are increasingly incorporated into contemporary fashion by Nigerian designers. The use of traditional techniques adds cultural depth and authenticity, appealing to both local and international audiences. Modern designers blend these age-old methods with contemporary styles, creating innovative and unique fashion pieces that reflect Nigeria’s rich heritage. This fusion has not only revitalized traditional craftsmanship but also positioned Nigeria as a global hub for Afrocentric fashion.
Unique Contribution to Theory, Practice and Policy: Cultural identity theory, sustainable fashion theory & brand equity theory may be used to anchor future studies on the effect of traditional textile techniques on modern fashion design in Nigeria. Fashion designers should collaborate with local artisans who specialize in traditional textile techniques. Policymakers should develop initiatives that support artisanal communities involved in traditional textile production.
Fashion’s New Frontier: Exploring the Post-Pandemic Shift Towards Sustainable Style in Malaysia
Authors: Hassan Normaziana binti , Taif Basitah , Tajuddin Rosita Mohd
Published: October 2024

The fashion industry, a crucial sector in the global economy, has undergone significant changes due to the COVID-19 pandemic. This health crisis disrupted traditional retail models, accelerated the adoption of e-commerce, and increased awareness of the environmental and social impacts of fashion consumption. In Malaysia, the pandemic caused a notable decline in foot traffic to physical stores, leading many retailers to pivot to online platforms to sustain operations. The rise in e-commerce was pronounced, with platforms such as Zalora and Shopee experiencing a surge in fashion sales. Concurrently, the pandemic heightened awareness of the environmental and social repercussions of fashion, fueling interest in sustainable fashion practices. This shift is reflected in the growing preference for eco-friendly materials and ethical production methods among Malaysian consumers. Local brands like Biji Biji Ethical Fashion and international labels such as H&M’s Conscious Collection have responded to this demand, incorporating sustainable practices into their offerings. Additionally, initiatives by the Malaysian government and industry stakeholders have supported the promotion of sustainability within the fashion sector. This study investigates the pandemic’s impact on fashion consumption patterns among Malaysian Millennials and Generation Z, focusing on changes in purchasing behaviors and attitudes toward sustainability. It identifies challenges including cultural awareness, affordability, and the dominance of fast fashion, while highlighting the need for educational initiatives and improved access to sustainable options. The findings provide valuable insights for academia, industry professionals, and policymakers aiming to advance sustainable consumption practices in Malaysia.
Effect of Podcast Instructional Methods on General Woodwork Students Retention and Ability in Technical Colleges in FCT, Abuja, Nigeria
Authors: S. Musa , Kareem W. B. , Mohammed B. M. , Saminu Shuaibu
Published: October 2024

The study sought to determine the effects of basic podcast and vodcast methods on Students’ Retention and Ability in General woodwork in Technical Colleges. Two research questions were raised and answered as well as two hypotheses were formulated and tested at 0.05 level of significance. The study adopted pretest–posttest non-equivalent control group design of quasi experimental and factorial design for the study. The study was conducted in Federal Capital Territory (FCT) Abuja, Nigeria. A simple random sampling technique was used to select two technical colleges with 126 students out of a population of 156 year two NTC II general woodwork students in the three technical colleges in FCT. Abuja. The instruments used for data collection was General woodwork Achievement and Retention Tests (GWWRAT). The selected schools are Federal Science and Technical College, Orozo 72 and Government Science and Technical College, Garki 54. The instrument was subjected to face and content validation by three experts. The reliability co-efficient of the instrument was determined as 0.78 using Kuder Richardson 20 (K-R 20). The data for the study was collected by the researcher with the help of two research assistance through physical administration of the instrument. The study employed the use of descriptive statistics using mean and inferential statistics using Analysis of Covariance (ANCOVA) to analyse the data and test the hypotheses. The study found out that, basic podcast and vodcast teaching technique had positive effect on the retention and ability of students taught general woodwork. The study recommended among others that general woodwork teacher should adopt the use of basic podcast and vodcast teaching technique to enhance students’ retention and ability.
Study the Effect of Calcined Temperature on Structural, Optical and Magnetic Properties for Cobalt Ferrite Nanostructure
Authors: Mohammed Ataa Jamal , Hamdan Suhad A.
Published: October 2024

In this work, CoFe2O4 nanostructure was synthesized from Cobalt and ferric nitrates and sodium hydroxide (NaOH) by hydrothermal method. Effect of heat treatment on the structural, optical, and magnetic properties of the resulting powder was studied at calcination 400°C and 600°C with different concentration of NaOH. The resulted products were characterized by X-ray diffraction (XRD), Field emission scanning electron microscopy (FE-SEM), Fourier transformed infrared (FTIR), UV–Vis absorption, and vibrating sample magnetometer (VSM) technique as synthesis and when calcination at 400°C and 600°C with different concentration of NaOH. The absorption spectra show CoFe2O4 nanostructure absorb the ultra violet area. The high temperatures of the calcination process results in the reduction in crystallite size that their average crystallite size is found (11-14.26) nm. The FE-SEM images indicated that particles were agglomerated and spherical shape and size between (23.6 - 57.9) nm expect the morphology is clearly a structure nanorods at 3M at 400 oC. The created CoFe2O4 nanostructure have demonstrated ferromagnetic behavior for all the samples behavior which was found in VSM results examination.
Effects of Cs-137 radiation on hydrophobic silica monolithic prepared by two precursors
Authors: Mohammed Ghufran Waleed , Al-sharuee Israa F. , Alrakabi Muhanad
Published: October 2024

Cesium (Cs-137) radiation energy was shined on two aerogel samples made from two different starting materials at room temperature and pressure three times a day for one hour, two hours, and twenty-four hours. G1 and G2 were used as silicic acid sources to fabricate the two different types of aerogel samples. G1 represents tetraethyl orthosilicate (TEOS), while G2 represents sodium silicate (Na2SiO3). Field emission scanning electron microscopy analysis revealed the morphological characteristics of the molecular bonds and the impact of irradiation on them. Fourier-transform infrared spectroscopy investigated the molecular bonds and their characterization before and after exposure to radiation. The samples made from TEOS at room temperature and pressure were not affected by radiation in either the FTIR or FESEM tests. However, the samples made from Na2SiO3 at room temperature and pressure showed that some of the peaks were disappearing because they were exposed to radiation. Also, the peaks of the CH3 functional group are associated with the hydrophobicity of the material. The homogeneity and uniformity for all samples are dominant, and the size of the colloidal particles is about 30-33 nanometers (nanometer structure), which is no different from the size of the particles before and after exposure to gamma rays.
Food safety risk assessment in Vietnam - Current situation and way forward
Authors: Tran Cao Son , Nguyen Tuan Thanh , Tran Huy Hieu ,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam
Published: October 2024

Risk assessment is an important scientific step in risk-based food safety (FS) management that has been applied in many countries. In Vietnam, despite being regulated by law, risk assessment activities have not been widely implemented due to inadequate attention and limited resources, which reduces its roles in FS management. Several challenges of FS risk assessment in Vietnam are related to institutional organizations, data management, human resources, and the characteristics of the food supply chain. This article aims to review the progress of risk assessment activities in Vietnam. Different risk assessments have been conducted for various chemical hazards such as pesticides, mycotoxins, preservatives, heavy metals, and environmental residuals, whereas fewer risk assessments have been implemented for microbial hazards, which were mainly focused on common food poisoning pathogens, like Salmonella, Staphylococcus aureus, and E. coli. This article also analyzes risk assessment models from countries and regions such as China, Japan, the United States, Europe, and ASEAN in order to identify the issues and challenges in Vietnam. Based on the review and analysis, we recommend that Vietnam take action to implement risk assessment activities as a tool for effective FS management.
Quantification of L-ornithine L-aspartate in health supplement by HPLC in combination with o-phthalaldehyde derivative technique
Authors: Nguyen Quang Hung , Nguyen Thu Trang , Nguyen Van Khoa , Vuong Quynh Hoa , Nguyen Thi Hoang Lan , Cao Cong Khanh , Mac Thi Thanh Hoa ,   National Institue for Food Control, Hanoi, Vietnam,   Vietnam National University of Agriculture, Hanoi, Vietnam,   National Institue for Food Control, Hanoi, Vietnam,   National Institue for Food Control, Hanoi, Vietnam,   Vietnam National University of Agriculture, Hanoi, Vietnam,   National Institue for Food Control, Hanoi, Vietnam,   National Institue for Food Control, Hanoi, Vietnam
Published: October 2024

Dietary supplements containing L-ornithine L-aspartate (LOLA) are on the rise. Thus, a simple, reliable method of analysis for determining LOLA has been developed, which helps to control product quality. In this study, a method for determining LOLA in dietary supplements by HPLC in combination with o-phtalaldehyde derivatives (OPA) was developed and validated. The study optimized conditions for extraction of LOLA from the matrix, then derived with OPA and chromatographic separation on column C18. The detection limits and quantitative limits of the method were conducted on low-content real samples, with LOD and LOQ values achieved at 6.0 and 20.0 μg/g, respectively. The method has good recovery (98 – 106%) and repeatability (1.32 – 3.50%) that meet the method performance requirements according to AOAC. The validated method has been applied to analyze LOLA content in dietary supplements at the National Institute for Food Control.
Preservation of chicken breast meat by ginger extract and ginger essential oil
Authors: Huynh Thi Phuong Loan , Nguyen Tong Ngoc Nhung , Doan Ngoc Thach Ky , Pham Duy Sang ,   Institute of Food and Biology, Can Tho University, Can Tho, Vietnam,   Kien Giang University, Kien Giang, Vietnam,   Institute of Food and Biology, Can Tho University, Can Tho, Vietnam,   Institute of Food and Biology, Can Tho University, Can Tho, Vietnam
Published: October 2024

The study aims to extend the shelf-life of chicken breast meat by different treatments, including: (i) ratio of ginger: water = 60:40, 70:30 and 80:20; (ii) ginger essential oil 6%, 10% and 14%; (iii) edible coatings formula (sodium alginate combined with ginger extract or ginger essential oil). The research evaluated the effect of these treatments on the physicochemical parameters (pH, color, shear force, drip loss) and microbiological indicators (E. coli and aerobic plate count) of chicken breast meat during the cooling storage. The results showed that the physicochemical parameters of chicken breast meat were not affected by different treatments, these parameters were well maintained during cooling storage (4 ± 1°C). Moreover, the ginger extract 70%, ginger essential oil 10% and the combination of ginger with an edible coating positively inhibit the growth of microorganisms. The total aerobic and E. coli plate count of samples, which were treated by these treatments, decreased within 7-10 days of cooling storage. Moreover, the chicken breast meat was treated with sodium alginate-ginger essential oil 10% had E. coli and the aerobic microbial plate count was within Vietnamese National Standards (TCVN 12429- 3:2021) during ten days of cooling storage.
Determination of sudan III using nitrogen and sulfur co-doped carbon quantum dots with fluorescence enhancement effect
Authors: Tran Ngoc Bich , Nguyen Hoang Minh , Nguyen Tuan Minh , Duong Tam Nhu , Tran Dong Duong , Le Viet Ngan , Vu Thi Trang , Pham Gia Bach , Nguyen Thi Anh Huong , Pham Thi Ngoc Mai ,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam
Published: October 2024

Sudan III, a synthetic azo dye, is commonly used for coloring oils, waxes, and various plastics. However, its unauthorized presence in food and food products poses serious health hazards, including potential carcinogenic effects. In this study, we investigated the application of nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) as a fluorescence sensor to detect trace amounts of sudan III. When exposed to trace amounts of sudan III, the fluorescence signal of N,S-CQDs was significantly enhanced. Under optimal conditions (pH 5.0 and an incubation time of 4 minutes), the fluorescence enhancement of N,S-CQDs showed a linear relationship with sudan III concentration in the range of 7.5 x 10-10 to 1.0 x 10-8 M, with a limit of detection of 2.0 x 10-10 M (equivalent to 0.07 ppb). The method demonstrated high accuracy (recovery from 91.5% to 103.5%), good reproducibility (RSD < 3.86%), and excellent selectivity for sudan III over other azo dyes. We successfully applied this developed method to analyze sudan III in chili sauce and chili powder samples, cross-checking differences between results less than 10% with LC-MS/MS analysis.
Premised research on dietary exposure to benzo[a]pyrene, acrylamide, and Nnitrosodimethylamine from common fried and grilled dishes in North Vietnam
Authors: Nguyen Thi Hong Ngoc , Bui Cao Tien , Ton Thu Giang , Tran Cao Son ,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   University of Science and Technology, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam
Published: October 2024

Fried and grilled cooking methods and the widespread consumption of certain dishes may expose the population to elevated levels of potentially carcinogenic compounds, such as benzo[a]pyrene (BaP), acrylamide, and N-nitrosodimethylamine (NDMA). This study aims to quickly estimate dietary exposure to these contaminants and assess the associated carcinogenic risk for several common Vietnamese fried and grilled dishes. The concentrations of the target compounds were obtained from the study showed that BaP, NDMA, and acrylamide are the groups of substances of greatest concern. The analytical results of 235 samples of meat and meat products (grilled/fried/smoked), seafood and seafood products (grilled/fried/smoked), processed oils, and potatoes showed that 12 samples detected acrylamide in the range of 5.0 – 162.0 µg/kg found in grilled/fried dishes and 5.0 – 4605 µg/kg for fried potatoes. Additionally, 204 samples detected NDMA in all groups in the range of 0.20 – 15.0 µg/kg, and 27 samples detected BaP in the range of 5.2 – 88 µg/kg in grilled/roasted food. Combined with information on food consumption patterns to estimate dietary exposure, four age groups were divided into under 6 years old, 6 – 18 years old, 18 – 50 years old, and over 50 years old, which showed that the consumption of processed foods by age groups was very different. In particular, the age group from 6 to 50 years old was the group that consumed the most of these foods (14.1 – 140 g/day). Specifically, up to 94.4% of people interviewed ate fried meat, 88.8% ate fried seafood and 85% ate fried potatoes. Risk characterization using the margin of exposure (MOE) and Cancer Slope Factor approaches indicate that certain dishes, such as grilled/smoked meat and fish, and deep-fried foods, may pose a significant cancer risk to Vietnamese consumers.
A comprehensive study on the production of potassium sorbate and sodium benzoate reference material in orange juice
Authors: Le Manh Hung , Dang Huu Cuong , Nguyen Nhu Thuong , Dang Thi Oanh ,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam
Published: October 2024

Controlling the content of preservatives in soft drinks is of paramount important for assessing their quality during production and consumption, as well as for ensuring consumer health. To effectively enhance laboratory capacity in preservatives analysis, the requirement for reference materials (RMs) of non-alcoholic beverages containing common preservatives such as potassium sorbate and sodium benzoate is fundamentally essential. This research was conducted to provide a procedure for the production of reference materials for potassium sorbate and sodium benzoate in orange juice. The concentration of potassium sorbate and sodium benzoate in the reference materials complied with Circular No.24/2019/TT-BYT which regulates the management and use of food additives. The two RMs of natural and flavored orange juice were homogeneous and stable, however, their quality and stability were strongly affected by the storage temperature. At a particular condition of 5°C, synthetic orange juice witnessed a higher stability than natural at 532 days and 318 days, respectively. Furthermore, an accelerated aging study demonstrated that at -20°C, the integrity of potassium sorbate and sodium benzoate in natural orange juice was identically maintained for a substantial period of almost 3 years (expected shelf life 1,049 days).
A comparative study of DPPH radical scavenging property and antiproliferative potential on human hepatic cancer (HepG2) cells of methanolic extracts from different parts of Ludwigia hyssopifolia and Ludwigia adscendens
Authors: Huynh Anh Duy , Huynh Phu Vinh , Nguyen Van Hoa , Nguyen Khanh An , Do Ly Ngoc Dung ,   College of Natural Sciences, Can Tho University, Can Tho, Vietnam,   College of Natural Sciences, Can Tho University, Can Tho, Vietnam,   College of Natural Sciences, Can Tho University, Can Tho, Vietnam,   College of Natural Sciences, Can Tho University, Can Tho, Vietnam,   College of Natural Sciences, Can Tho University, Can Tho, Vietnam
Published: October 2024

Ludwigia hyssopifolia and Ludwigia adscendens are two indigenous and common plant species in Vietnam with hepatoprotective property mentioned in numerous articles published in international journals. Therefore, the current paper aimed to evaluate the physicochemical parameters, total polyphenolic and flavonoid contents of the methanolic extracts from 04 parts of Ludwigia hyssopifolia and Ludwigia adscendens in Mekong delta, Vietnam. Most importantly, antioxidant properties by DPPH radial scavenging assay and antiproliferative potentials on human hepatic cancer (HepG2) cells of these multiple extracts also were determined in the in vitro models. These results showed that physicochemical parameters were within allowable limits according to the literatures. Among the investigated samples, the leaf and whole plant extract from Ludwigia hyssopifolia had the highest values of total phenolic and flavonoid contents being 196.55 ± 5.05 mg GAE/g and 64.72 ± 4.63 mg QE/g respectively. Additionally, the methanol whole plant extract of Ludwigia hyssopifolia and the methanol leaf extract of Ludwigia adscendens show the greatest antioxidant properties in DPPH scavenging assay with IC50 values of 44.48 ± 4.29 µg/mL and 26.11 ± 0.37 µg/mL respectively. Furthermore, the methanolic extract from Ludwigia hyssopifolia leaves displays the most potential anti-HepG2 activity among all surveyed samples. Therefore, the most promising extracts need further evaluation for potential herbal product developments.
Tingkat Pengetahuan Siswa Tentang DAGUSIBU Dengan Metode Edukasi Di SMK N 7 Surakarta
Authors: Puspitasari Yunartika
Published: October 2024

DAGUSIBU adalah singkatan yang merangkum prinsip-prinsip penting terkait penggunaan obat dengan aman dan bertanggung jawab. Permasalahan DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) obat pada remaja melibatkan sejumlah tantangan yang dapat mempengaruhi kesehatan dan kesejahteraan remaja. Penyalahgunaan obat-obatan, baik obat resep maupun obat bebas, menjadi masalah serius di kalangan remaja. Remaja mungkin menggunakan obat tanpa resep untuk mengatasi stres, kecemasan, atau tekanan sosial, tanpa mempertimbangkan konsekuensi jangka panjang. Hal ini bisa berdampak negatif terhadap keselamatan diri remaja dan orang lain di sekitar remaja. Penelitian ini menunjukkan bahwa metode edukasi efektif dalam meningkatkan pengetahuan siswa tentang praktik DAGUSIBU. Pendekatan terintegrasi dan berkelanjutan diharapkan dapat membentuk pengetahuan yang lebih baik dan menciptakan lingkungan sekolah yang mendukung pengambilan keputusan bijak terkait penggunaan obat.