bluuebunny/crossref_metadata_2025 huggingface dataset:
Colony-forming endothelial cells – candidate culture for tissue vascular engineering: the gene and proteomic profile
Authors: Khanova M. Yu. , Kutikhin A. G. , Matveeva V. G. , Velikanova E. A. , Krivkina E. O. , Antonova L. V.
Published: January 2024

Aim. To validate ECFC culture as a candidate culture for vascular tissue engineering using comparative analysis of the proteomic and gene expression profiles in comparison with cultures of human umbilical vein endothelial cells (HUVEC) and human coronary artery endothelial cells (HCAEC).

Materials and Methods. ECFC culture was obtained by cultivating peripheral blood mononuclear cells of patients with coronary artery disease. Commercial HCAECs produced by Cell Applications, and HUVECs cultured according to the modified protocol of Jaffe were used as controls.

The cells were lysed with TRIzol, and total RNA was isolated using a Purelink RNA Micro Scale Kit with concomitant DNase treatment. Next, rRNA depletion was carried out, followed by the creation of DNA libraries. DNA libraries were quantified using quantitative polymerase chain reaction on a CFX96 Touch Bio-Rad amplifier. DNA libraries were equimolarly mixed and sequenced on HiSeq 2000 (Illumina) with a paired-end reads of 2x125 nucleotides.

Conventional western blotting was performed using pan-endothelial markers CD31, vWF, VEG-FR2/KDR, marker of endothelial progenitor cells CD34, markers of epithelial-mesenchymal transition Snail and Slug, and markers of endothelial specification: arterial HEY2, venous COUP-TFII and lymphatic LYVE1, VEGFR2. Dot blotting against 55 angiogenesis-related proteins was performed using Proteome Profiler Human Angiogenesis Array Kit in accordance with the manufacturer's protocol.

Results. ECFC overexpresses markers of all three endothelial lineages (KDR, VWF, CD34, NRP2, FLT4 and LYVE1 compared to HCAEC; NOTCH4, DLL2) and LYVE1 compared to HUVEC. Proteomic profiling indicated ECFC as an intermediate population between HCAEC and HU-VEC in term of the expression of HEY2, LYVE1, VEGFR3, Snail and Slug. 261 DEGs were detected between ECFC and HUVEC, and 470 DEGs between ECFC and HCAEC.

Conclusion. The gene expression profile of endothelial colony-forming cells corresponds to mature endothelial cells and indicates ECFC as an intermediate population between HCAEC and HUVEC. ECFC culture can be recommended for tissue vascular engineering.
Hygienic assessment of the consumption of trans fatty acids by the population of the Omsk region
Authors: Chubarova A. D. , Turchaninova M. S. , Gogadze N. V. , Vilms E. A. , Shcherba E. V.
Published: January 2024

Aim. Assessment of the content of trans-fatty acids in foods consumed by the population of the Omsk region and the values of their actual consumption.

Materials and Methods. The results of laboratory studies of food products from the following groups were analyzed: fast food (hamburgers, french fries, chips); confectionery; oils, fats; meat products; dairy products (n=438). In product samples, the mass fraction of trans-fatty acid isomers was determined by gas chromatography. An assessment was made of the actual nutrition and consumption of trans fats by the inhabitants of the region using the method of analyzing the frequency of food consumption (n=441).

Results. The median content of trans fats in the main food groups was 0.67% of total fat, which does not exceed the values recommended by WHO. There was a decrease in the content of trans-isomers in food products from 2.7% in the period 2016−2017. up to 1.0% in the period 2020−2021 However, there remains a significant health risk associated with the consumption of trans-fatty acids, due to the high proportion of samples exceeding the recommended levels (24.5±2.1%), to a greater extent the risk was determined by the consumption of confectionery. The median consumption of TFAs in the study population was 1.16 g, which is in line with the recommended norms. The proportion of people with excess recommended consumption was 10.2%.

Conclusion. The results indicate an improvement in the situation related to the consumption of trans fats in 2016-2021 due to stricter requirements for their content in food products. It is necessary to conduct further research related to the assessment of the content of trans-isomers of fatty acids in the diet of various population groups to identify risk groups and priority food products - sources of trans fats.
Songs to learn and sing
Authors: Cloonan Martin
Published: January 2024

Based on over 50 years of the author watching Liverpool FC (LFC) football matches, this article examines the use of songs in and around such matches, locating it within wider debates about the use of song at football matches.The development of modern media’s relationship to football will be considered in three main areas – the importance of television in the modern age, the availability of songs on the internet and the use of the sound systems to control fan behaviour at matches. The article aims to provide some insights in to one of the most important – but often neglected – aspects of football fandom. It does so by examining the place of Liverpool Football Club (LFC) within the city, football and the media, fandom, singing at football matches and the particular nature of LFC songs. The article concludes by suggesting that it is in the singing of songs that true football fandom is found.Keywords: singing at football matches, Liverpool FC, popular music, football fandom, Spion Kop
Venice's Economic Diplomacy: Timeless Lessons for Contemporary Global Challenges
Authors: Papastamou Andreas
Published: January 2024

Several authors have explored the role of Venice in diplomacy, given the city-state’s historical significance as a major maritime and trading power. Could the Venice experience teach us about economic diplomacy today? Venice, during its heyday as a maritime republic and a major economic power in the Mediterranean, offers several lessons in economic diplomacy that remain relevant today. While the historical context differs, the principles underlying Venice’s economic success and diplomatic strategies can provide insights into contemporary international relations and economic diplomacy.
The Teacher Professional Education Students' Perception on Learning Management System-based Online Learning
Authors: Ramdhan Dadan F , Siregar Hariman Surya
Published: January 2024

This research aimed to investigate the perceptions and impacts of online learning utilizing the SPACE (Electronic religious learning system application) among students enrolled in Teacher Professional Education (TPE) programs at State Islamic Religious Colleges. Employing a quantitative approach, the study utilized linear regression analysis and structural equation modeling through AMOS 23. Effectiveness was gauged using indicators proposed by Robert E. Slavin, encompassing quality of learning, appropriateness of learning level, intensity, and time. The study participants comprised students across three Teacher Professional Education Study Programs. The findings revealed that nearly all participants expressed ease in learning and perceived the modules within SPACE as more effective. They also indicated that the materials/modules in SPACE aligned well with the needs of TPE participants and found the learning procedures within SPACE easy to follow. Notably, incentive variables within implementation indicators had a direct influence on perceived ease of use (user convenience), subsequently impacting the perceived usefulness variable. For future research, integrating direct interview data from students and conducting comparative analyses between offline and online implementations in professional education would provide valuable insights.
The Kyai’s Strategy to Develop Cadres with Islamic Characters
Authors: Iman Nurul , Ikhwan Afiful , Fadilah Nur Hidayatul
Published: January 2024

This article aims to explain the Islamic character regeneration model in Islamic boarding schools and the strategy of the kyai as the highest leader in developing Islamic character regeneration for students. The location of this research, namely Arrisalah Modern Islamic Boarding School Ponorogo, is unique from other sites because of the curriculum or general subjects at the Islamic boarding school, which is famous for its salaf curriculum, which is integrated with Islamic values typical of Islamic boarding schools. This study uses an interpretive paradigm through a qualitative approach, a case study type. The primary data were obtained from caregivers, madrasa heads, teachers, students, and other parties involved, using data collection techniques such as in-depth interviews, observation, and documentation. The analysis technique used is the Miles and Huberman data reduction models, data display, and verification. Checking data validity using triangulation: credibility, transferability, dependability, and confirmability. The study results show that the cadre model at Arrisalah Modern Islamic Boarding School is a reduction or transfer of the Islamic boarding school's Islamic character and values. The kyai's strategy in creating cadres with Islamic character is actualized in several aspects, including the kyai's example, curriculum, 'Ala Manhaj Rabbaniy education system, organization, Pondok discipline, and compulsory service. So, this research provides a lot of valuable insights into the cadre model in Islamic boarding schools, and it cannot be denied that there are still various opportunities for more in-depth and broad future research.
Simulación de procesos y evaluación ambiental de la producción de un bioadsorbente modificado con quelantes y nanopartículas magnéticas
Authors: Bertel Pérez Forlin , Cogollo Cárcamo Grisele , González Delgado Ángel Darío
Published: January 2024

Las estrategias de valorización de residuos son clave para lograr una producción más sostenible dentro de la industria de mariscos. El quitosano es un biopolímero que cuenta con múltiples aplicaciones en sectores como agricultura, la industria alimentaria, cosmética, sistemas detratamiento de agua, entre otros. Los residuos de la industria de los mariscos pueden ser aprovechados en la síntesis de quitosano, convirtiéndose en una alternativa de valorización de residuos. Uno de los usos alternativos del quitosano es como precursor para la preparación de bioadsorbentes modificados con el fin de eliminar contaminantes. En este trabajo, se desarrolló la evaluación ambiental del proceso de obtención a escala industrial de un bioadsorbente de quitosano funcionalizado con nanopartículas de magnetita y un quelante (tiourea), con el objetivo de evaluar los posibles impactos ambientales. Se utilizó el software Aspen Plus ® para la simulación del proceso, que permite la cuantificación de flujos másicos y estimación de propiedades. El análisis ambiental se realizó utilizando el Algoritmo de Reducción de Residuos (WAR) a través del software WAR GUI. Los resultados mostraron que el proceso consume impactos ambientales potenciales (PEI), obteniendo un valor positivo de 1.870 PEI/h. Las categorías relacionadas con los impactos toxicológicos (HTPI, HTPE, TTP y ATP) presentaron menores valores que las relacionadas con impactos atmosféricos (GWP, ODP, PCOP y AP), siendo las de mayor contribución toxicidad humana por ingestión (HTPI) y la toxicidad potencial terrestre (TTP), categorías que se encuentran asociadas a la dosis letal media (LD50) de los compuestos involucrados en el proceso. Se determinó consumo de PEI usando como fuente energética gas natural.
Simulación dinámica computacional en tanques agitados de fondo cónico con turbina Rushton y de palas inclinadas
Authors: Cardona Palacio Luis Fernando , Arismendy Juan E. , Quintana Marín German Camilo , Alzate Gil Hader Humberto , Hincapié Diego A.
Published: January 2024

La Dinámica de Fluidos Computacional (CFD en inglés) es una herramienta de uso frecuentepara la optimización y mejora de procesos. En este trabajo se utilizó la simulación CFD paraanalizar la potencia más apropiada en sistemas agitados con tres diferentes tipos de conosen el fondo del tanque y con dos tipos de impulsores: turbina de 4 palas inclinadas a 45°(impulsor axial) y turbina Rushton estándar (impulsor radial). La simulación se realizó en untanque agitado con un diámetro de 27 cm y se analizó diferentes proporciones del diámetroy altura del cono. Además, se evaluaron 4 velocidades de giro (50, 100, 300 y 600 rpm) paradescribir el estado de transición a turbulento. Se utilizó el modelo de esfuerzo de Reynolds(RSM en inglés) con un sistema de referencia móvil. Los resultados de este estudio indicanque hay disminución de la potencia con el impulsor de tipo axial a bajos números de Reynoldsmientras que para el impulsor de tipo radial se presenta un aumento en los valores de potenciacuando se incluye el cono dentro del tanque. Al incrementar el número de Reynolds se tieneun incremento exponencial de la potencia-volumen de cada impulsor. Además, la inclusiónde un impulsor de 4 palas inclinadas en un régimen entre laminar y transición evidencia unahorro significativo en el consumo de potencia y para regímenes turbulentos la inclusión degeometrías en el fondo del tanque afecta el consumo de potencia. Finalmente, los resultadosson validados utilizando datos experimentales y muestran que las desviaciones absolutas sonmenores al 4 %.
Impacto en la salud causado por los nanoplásticos contenidos en alimentos y su posible atenuación mediante un proceso de bioingeniería
Authors: Erazo Ordóñez María Jimena , Révérend Lizcano Carlos Arturo
Published: January 2024

A través de los siglos, las poblaciones de seres humanos asentadas en los alrededoresde a�luentes hídricos han dispuesto indiscriminadamente sus desechos arrojándolosa los ríos, lagos, océanos, y terrenos aledaños. Cuando las cantidades de desechos, ensu mayoría biodegradables son bajas, las consecuencias ambientales y sobre la saludde las comunidades bióticas son mínimas. Sin embargo, la fabricación y disposiciónen masa de materiales sintéticos no biodegradables desde mediados del siglo XX hatenido profundos efectos biológicos y ambientales. Los plásticos son el ejemplo mássigni�icativo de estos ubicuos materiales sintéticos, usualmente de un solo uso, nobiodegradables y con altas cantidades de aditivos químicos tóxicos. Debido a la altaestabilidad y resistencia del plástico, es imposible vincularlo rápidamente enprocesos que permitan su degradación y descomposición; por ello, se han convertidoen la mitad de los residuos que hoy existen en el planeta. La deriva de estosmateriales conlleva a que, bajo condiciones ambientes, paulatinamente se vayanfragmentando en partículas alcanzando las escalas de los micrómetros y losnanómetros, a estas partículas se les ha categorizado como contaminantesincidentales: micro y nanoplásticos. Hoy en día, el mundo contempla el boom de lananotecnología y cada vez más industrias se interesan por el uso de esta tecnologíaemergente; producen micro y nanoplásticos de manera intencional para serincorporados en productos cosméticos, �ibras textiles, entre muchos otrospropósitos. La contaminación de estas partículas plásticas de dimensionesimperceptibles, llega a los alimentos de consumo humano a través de la persistenciaen los ecosistemas y la bioacumulación, por diferentes vías de exposición, principalmente por ingesta en las diferentes cadenas que componenla red trófica mundial, además, de la migración del material empleado para elalmacenamiento, preservación y empaque de los alimentos. Los nanoplásticos yalgunos microplásticos al ser ingeridos atraviesan las barreras físicas epiteliales yse distribuyen por todo el organismo ingresando en prácticamente todos los tejidoscorporales, alterando su funcionamiento y aumentando la carga de enfermedad delas comunidades bióticas incluyendo la humana. Al ser considerados materialesinertes y heterogéneos, su identificación y recuperación es compleja, además deno ser completamente efectiva. El presente escrito busca revisar informaciónque permita evaluar el impacto de los nanoplásticos presentes en los alimentos,resaltando los efectos tóxicos que poseen estos materiales para la salud humanaa través de la bioacumulación y biomagnificación en las cadenas tróficas a nivelbiomolecular subcelular y, por otro lado, describir las técnicas de recuperación delos nanoplásticos para reducir su presencia en los alimentos.
Impact of the ENSO phenomenon on dissolved oxygen at two stations on the Cauca River-Colombia: 1985 to 2015
Authors: Diaz Escobar José Alfredo , Guamialamag-Alpala Diana Ximena , Vargas-Franco Viviana
Published: January 2024

Climate variability is one of the main challenges faced by mankind, andunderstanding its relationship with water quality will generate knowledge that willenable the development of early adaptation strategies and the integral managementof water resources. This study assessed the impact of the different intensities of the“El Niño-Southern Oscillation” (ENSO) climate phenomenon on Dissolved Oxygen(DO) from 1985 to 2015, at two monitoring stations on Cauca River. Spatialtemporal variation analysis of DO was performed using descriptive and inferentialstatistical techniques under different ENSO phases. The correlation betweenDO and the intensities of the ENSO phases was assessed using the Spearmancorrelation coefficient. No statistical differences were found in DO concentrationat the two studied stations (p = 0.1164). Statical differences of DO were founddepending on the ENSO phases at the Mediacanoa station (p = 0.002556); it wasalso found that the highest median concentrations of DO took place when LaNiña was present. No correlation was found at the studied stations between theintensities of the ENSO phases and DO. The water quality of the Cauca River, at theYotoco and Mediacanoa stations, showed very poor conditions, which has producednegative social, economic and environmental effects.
Análisis de la Integración del Hidrógeno en Sistemas Híbridos de Energía Renovable en el marco de Escenarios Energéticos
Authors: Garcia Andres , Jaramillo Andres , Angel Enrique , Ortega Santiago
Published: January 2024

El hidrógeno como vector energético puede brindar energía en aplicaciones desde baja hasta gran escala y aporta al impulso de las energías renovables como alternativas de emisiones bajas en carbono. Este trabajo presenta una revisión de literatura sobre los sistemas híbridos de hidrógeno verde. Se encontró que un 23% de los artículos realizan revisiones de diferentes metodologías y comparaciones de tecnologías de hidrógeno, el 15% presentan análisis técnicos, económicos y ambientales de sistemas y proyectos basados en hidrógeno. El 53% de los artículos revisados se concentran metodologías de inteligencia artificial y uso de programas computacionales comerciales para el dimensionamiento, gestión de la energía y optimización de estos modelos sobre los sistemas híbridos de energía renovable con un alto enfoque en sistemas aislados de la red eléctrica. El potencial de modelos de simulación por desarrollar en este tema es bastante amplio por la descarbonización que aporta el hidrógeno. Los modelos deben contemplar aspectos adicionales de toda la cadena de valor del hidrógeno para tener una visión íntegra de su desarrollo en Colombia, tendiendo en cuenta las oportunidades de desarrollo en el marco de diferentes escenarios energéticos.
Использование инбридинга в суксунской породе крупного рогатого скота
Authors: Кавардакова Оксана
Published: January 2024

В статье определена зависимость хозяйственно-полезных качеств коров от применения различных методов спаривания. Показана оценка продуктивных качеств инбредных животных, которая по удою, белковомолочности и живой массе является лучшей, чем у коров, полученных при неродственном спаривании. Отмечено отрицательное влияние инбридинга на воспроизводительную способность животных. Подтверждено положительное влияние степени инбридинга на содержание жира в молоке анализируемого поголовья. Выявлено, что аутбредные животные имели небольшую массу при рождении, которая способствует лучшему протеканию отела первотелок.
Influence of Internet Addiction on Pre-Service Mathematics Teachers’ Learning and Motivation in Nigerian South-West Universities
Authors:   Department of Science Education, Faculty of Education, University of Lagos, Nigeria, Akinoso Sabainah Oyebola
Published: January 2024

The widespread use of the internet has led to a growing concern about the impact of internet addiction on pre-service Mathematics teachers' learning. This paper investigates the impacts of internet addiction on the learning and professional development of pre-service Mathematics teachers. The population covers the undergraduate Mathematics education students from public universities in south-west Nigeria. The sample was randomly selected from 100 to 400 levels while the sample size was 200 pre-service teachers across the levels from one selected university. A well-structured questionnaire was used to get data from pre-service Mathematics teachers on internet addiction. This study employed a descriptive and inferential research design to create responses to the research questions. The data collected were analysed using mean and standard deviation for the two research questions while Pearson Product Moment Correlation Coefficient was used to test the hypothesis raised. There is a significant relationship between internet addiction and Mathematics learning. This yields a positive result that, the students who access the internet more frequently learn more effectively and highly motivated in learning Mathematics. It was suggested that the internet can be a useful tool for learning but must be used responsibly. However, addressing internet addiction through education, prevention, and intervention efforts should be integrated into the teacher education program to support pre-service mathematics teachers in developing healthy internet use habits and maintaining high levels of motivation to learn.
Relationship between Achievement Goal Orientation, Fear of Failure and Academic Performance
Authors:   Alexandru Ioan Cuza University, 11 Carol Boulevard, Iasi, Romania, Leonte Roxana-Elena
Published: January 2024

There is considerable empirical support for the study of factors that positively or negatively influence academic performance, including achievement goal orientation and fear of failure. According to research, fear of failure can, in some situations, threaten students' academic performance by affecting their engagement in learning activities. If remedial action is not taken to reduce it, this can affect students academic future. At the same time, earlier research has indicated that fear of failure influences thenature of achievement goals that students pursue. Nevertheless, there is a scarcity of studies that have explored the connection interplay between learning goal orientation, the fear of failure, and academic achievement. Based on data from 120 university students, we conducted correlational analyses to test the relationships between achievement goal orientation, fear of failure and academic performance. The findings showed significant correlations between fear of failure and mastery-avoidance goal, as well as between students' academic performance. Pedagogical implications and future research directions were discussed.
Pathways to Life Skills in High Schools and Universities-Teachers’ Perceptions and Experiences
Authors:   „Lucian Blaga” University of Sibiu, Romania, Dumulescu Daniela
Published: January 2024

Education needs to reshape the individual's role in the societies of the future. In an unknown world of different technologies, job requirements, and societal structures, the current education systems may not be sufficient to equip young generations with
PENGARUH IMBANGAN SUSU UHT DAN JUS KURMA TERHADAP JUMLAH BAKTERI, TOTAL YEAST DAN AKTIVITAS ANTIOKSIDAN PADA PRODUK SUSU KURMA
Authors: Rizkika Meisha Ayudia Rahma , Wulandari Eka , Utama Dicky Tri
Published: January 2024

Ultra High Temperature (UHT) milk or packaged milk is milk that is processed through heating that exceeds the pasteurization process, which refers to a certain combination of time and temperature to obtain a sterile commercial product. The addition of date juice to date milk products will cause changes both physically, chemically, and microbiologically. This study aims to determine the best concentration of date palm juice on date milk products with the lowest number of bacteria and total yeast and the highest antioxidant activity. This research was conducted in January 2023 at the Laboratory of Animal Product Processing Technology, Padjadjaran University, Sumedang. The study was conducted experimentally with a completely randomized design (CRD) using 3 treatments and 6 replications with the percentage of date juices consisting of P1 (10%), P2 (20%) and P3 (30%). The research data were analyzed using analysis of variance and Duncan's multiple range test for the parameters of the number of bacteria, total yeast and antioxidant activity. The results showed that the addition of 30% date palm juice had the best effect on the number of bacteria and total yeast, and antioxidant activity. The best addition of date palm juice is at a concentration of 10% with total bacteria 4,54× 10 4 total yeast 3,25× 10 5 dan antioxidant activity 242,63 ppm.
Ciudades y regiones para una economía azul
Authors:   Jefa de la Unidad de Gobernanza de Agua y Economía Azul y Circular, Centro de la OCDE para el Emprendimiento, Pymes, Regiones y Ciudades (CFE), Romano Oriana , Lassman Juliette ,   Analista de políticas, Unidad de Gobernanza de Agua y Economía Azul y Circular, Centro de la OCDE para el Emprendimiento, Pymes, Regiones y Ciudades (CFE), Laimé Georges ,   Analista adjunto de políticas, Unidad de Gobernanza de Agua y Economía Azul y Circular, Centro de la OCDE para el Emprendimiento, Pymes, Regiones y Ciudades (CFE)
Published: January 2024

La economía azul puede ser un motor de desarrollo económico sostenible, pero está expuesta al cambio climático y el deterioro ambiental, al tiempo que contribuye a ellos. La salud de los océanos depende de la salud del agua dulce, pero las políticas sobre los medios marinos y los de agua dulce no están interconectados. La seguridad hídrica es un punto ciego de las estrategias sobre la economía azul. Los gobiernos subnacionales son competentes en áreas políticas que pueden mejorar la calidad del agua: saneamiento, gestión de residuos y ordenación territorial; además, sus responsabilidades de inversión en materia de infraestructura verde y gris pueden favorecer la resiliencia ante los crecientes riesgos hídricos.
Adaptive Integration of Convex Functions of One Real Variable
Authors: Wąsowicz Szymon
Published: January 2024

We present an adaptive method of approximate integration of convex (as well as concave) functions based on a certain refinement of the celebrated Hermite–Hadamard inequality. Numerical experiments are performed and the role of harmonic numbers is shown.
Note on an Iterative Functional Equation
Authors: Baron Karol , Morawiec Janusz
Published: January 2024

We study the problem of solvability of the equation

ϕ

(
x
)

=

∫
Ω

g

(
w
)

ϕ

(

f

(

x
,
ω

)

)

P

(

d
ω

)

+
F

(
x
)

,

\varphi \left( x \right) = \int_\Omega {g\left( w \right)} \varphi \left( {f\left( {x,\omega } \right)} \right)P\left( {d\omega } \right) + F\left( x \right),

where P is a probability measure on a σ-algebra of subsets of Ω, assuming Hölder continuity of F on the range of f.
Active 6 DoF Force/Torque Control Based on Dynamic Jacobian for Free-Floating Space Manipulator
Authors: Dyba Filip , Rybus Tomasz , Wojtunik Mateusz , Basmadji Fatina Liliana
Published: January 2024

In-orbit capture of a non-cooperative satellite will be a major challenge in the proposed servicing and active debris removal missions. The contact forces between the manipulator end-effector and the elements of the target object will occur in the grasping phase. In this paper, an active 6 Degrees of Freedom (DoF) force/torque control method for manipulator mounted on a free-floating servicing satellite is proposed. The main aim of the presented method is to balance the relation between end-effector position and force along each direction in the Cartesian space. The control law is based on the Dynamic Jacobian, which takes into account the influence of the manipulator motion on the state of the servicing satellite. The proposed approach is validated in numerical simulations with a simplified model of contact. Comparison with the classical Cartesian control shows that the active 6 DoF force/torque control method allows to obtain better positioning accuracy of the end-effector and lower control torques in manipulator joints in the presence of external forces.
Hasil Interpretasi Problematika Kesetaraan Gender dalam Proses Kreatif PenciptaanTari
Authors: Sari Yussi Ambar
Published: January 2024

Jenis kelamin secara biologis merupakan kodrat Tuhan, sedangkan gender merupakan perbedaan yang bukan biologis dan bukan kodrat Tuhan. Gender merupakan perbedaan perilaku antara laki-laki dan perempuan yang dikonstruksi secara sosial, bukan berdasarkan kodrat dari Tuhan melainkan diciptakan oleh manusia melalui proses sosial dan kultural yang panjang. Keluarga memiliki berbagai macam aturan, mulai dari cara belajar, pergaulan, norma, tanggung jawab, ibadah, dan tata krama (sopan santun atau etika). Ketika perempuan mulai menyadari bahwa mereka memiliki permasalahan dan pengalaman yang sama, mereka menggunakan pemahaman untuk menentang cara memahami dunia yang sudah lama ada tetapi tidak sesuai dengan pengalaman yang mereka alami dalam memahami dunia. Berdasarkan pengalaman empiris koreografer tanggapan tersebut membuatnya berontak pada beberapa aturan keluarga, khususnya aturan yang dibuat oleh seorang ayah yang lebih protektif terhadap putrinya. Para feminis memandang bahwa keluarga adalah sumber kunci penindasan yang mereka alami Jika semua hal diatur seperti robot, kurang fleksibel terhadap perubahan hidup, sangat memungkinkan adanya pemberontakan terhadap aturan yang mengekangnya. Kata Kunci: Gender, Pengalaman Empiris, dan Feminis.
Farmers’ access to agricultural information through radio and television: the case of Menoua division in West Cameroon
Authors:   Department Of Rural Socio-Economics And Agricultural Extension, B Ndemdou
Published: January 2024

Five opportunities to access agricultural information provided by radio and television have been named: the specialized agricultural programs, the reading of announcements, advertisements, news program and the programs that are not specialized in agriculture. Farmers consider that the information they receive from these channels is useful for their work.
Brief Commentary and Based on the Article Entitled “Ultrasound-Guided Electroacupuncture Treatment for Rotator Cuff Tendinopathy: Proposing an Effective Alternative to Non-Operative Medical Treatments”
Authors:   Christiana Care, Stewman Chaney G
Published: January 2024

Specifically, it utilizes ultrasound to see areas of injury/pathology within the rotator cuff tendon(s) and ultrasound to visualize acupuncture needle placement into these areas
Effect of a Short-Term Integrative Program on Quality-of-Life of Breast Cancer Patients and Survivors
Authors:   Rehabilitation Medical Hospital – Medical Care, Meshulam Vered Atzmon
Published: January 2024

An integrative intervention can provide non-pharmacologic recovery support that optimizes QoL and reduces the symptom burden in breast cancer patients and survivors
Assessment of Sheep Production and Marketing System in Jimma Geneti Wereda, Horo Guduru Wollega Zone of Oromia Regional State, Western Ethiopia
Authors:   Department of animal science, Ale Abera Teshome
Published: January 2024

The study was conducted in Jimma Geneti district to assess production and marketing system of sheep. Three kebeles were randomly selected as sample kebeles from which sample respondents were purposively selected based on their potential
Chronic cough and refractory chronic cough: An important distinction
Authors: Dicpinigaitis Peter V.
Published: January 2024

Cough is the most common concern for which patients in the United States seek medical attention. Cough is typically classified according to its duration: acute cough (<3 weeks), subacute cough (3‐8 weeks), and chronic cough (>8 weeks). The vast majority of cases of acute
cough in patients are due to an acute viral upper respiratory tract infection (common cold) and are self limited. Subacute cough is often due to a prolonged postviral cough. Once a cough meets the definition of chronic, it becomes likely that the cough is due to one or more treatable underlying
etiologies: upper airway cough syndrome (formerly, postnasal drip syndrome), asthma and non-asthmatic eosinophilic bronchitis, and gastroesophageal reflux disease. Refractory chronic cough (RCC) refers to chronic cough that persists despite adequate therapeutic trials aimed at the known causes
of chronic cough. The term cough hypersensitivity syndrome has recently been introduced to stress the concept that RCC is a distinct disease entity due to vagal hyperactivity causing hypersensitivity of the cough reflex. No medications have ever been approved for chronic cough or RCC in the
United States and most of the world. Thus, physicians are limited to the use of off-label medications for their patients with this chronic and often debilitating condition. However, recent insights into the mechanisms of cough have resulted in multiple molecules currently being evaluated as
potential antitussives. Among these, furthest along in the drug development pipeline are the P2X3-antagonists, of which, gefapixant has completed phase III trials, and camlipixant is currently in phase III studies.
Pérez, Alberto Julián. La literatura de la conquista del Río de la Plata. Letra Minúscula, 2022. 238 pp.
Authors: Solodkow David
Published: January 2024

Review of Pérez, Alberto Julián. La literatura de la conquista del Río de la Plata. Letra Minúscula, 2022. 238 pp.
Ferrada, María José. Diario de Japón. Planeta, 2022, 187 pp..
Authors: Urriago Hernando
Published: January 2024

Review of Ferrada, María José. Diario de Japón. Planeta, 2022, 187 pp.
Synthesis of Cinnamoylhydroxamic Acid Derivatives Bearing Sulfonamide, Amide Bonds as Connecting Unit Targeting Histone Deacetylases
Authors: Quoc Nguyen Cuong , Quang Le Dang , Tuan Nguyen Duy , Khang Tran Duy , Linh Nguyen Vu , Men Tran Thanh , Tuan Nguyen Trong , Hue Bui Thi Buu , De Tran Quang
Published: January 2024

Based on the strong activity of belinostat, the study synthesized of some cinnamoylhydroxamic acid derivatives with the aim of creating new compounds that have the potential to selectively inhibit HDAC to contribute to cancer treatment.  N-hydroxycinnamamide serves as both ZBG and the linker group. The derivatives orient to the HDAC2 and HDAC8 enzymes by molecular docking. Compound 9a (bearing sulfonamide) exhibited as the most potential candidate to inhibit the function of HDAC2 enzyme.
Large-Scale Deletions of Mitochondrial DNA in Epilepsy Patients Treated with Carbamazepine
Authors: Thi Tu Linh Nguyen , Huong Vu Thu , Nhan Le Thi Thanh , Phuong Le Lan , Thuy Nguyen Doan , Lieu Nguyen Van , Anh Nguyen Thi Van , Thai Trinh Hong
Published: January 2024

Mitochondrial dysfunction, caused by large-scale deletion mutations, can lead to impaired function of the mitochondrial respiratory chain, reduced ATP production, and serious effects on most energy-consuming organs, such as neurons, and can induce seizures in epilepsy. Carbamazepine (CBZ), the first-line drug used in the treatment of epilepsy, can be harmful to mitochondria and its side effects may be related to mitochondrial dysfunction. In this study, mitochondrial DNA (mtDNA) large-scale deletions were identified in 65 CBZ-treated patients with epilepsy, including 32 patients with CBZ-induced hypersensitivity and 33 with CBZ tolerance. Using the PCR method, mtDNA large-scale deletions were identified in 21/65 epilepsy patients (32.31%), including 9/32 CBZ-hypersensitivity patients (28.13%) and 12/33 CBZ-tolerance patients (36.36%). However, this difference was not statistically significant. The “common deletion” of 4977 bp was the most prevalent deletion. Remarkably, the new deletion of 4876 bp in a CBZ-tolerance patient was reported for the first time. Quantitative PCR analysis showed that the level of mtDNA large-scale deletion was significantly lower in the hypersensitivity group than in the tolerance group (p < 0.05). Besides, analysis of the association between the level of mtDNA large-scale deletion and mtDNA copy number with the clinical features of CBZ hypersensitivity patients showed no relationship with age and severity of skin lesions (p > 0.05). However, there was a statistically significant association between the level of mtDNA large-scale deletions and sex (p < 0.01). Further studies are needed to evaluate the role of mtDNA large-scale deletions in epilepsy and their association with antiepileptic drugs.
Synthesis of Graphene Aerogel for Adsorptive Removal of Tetracycline from Water: Impact of Operating Parameters
Authors: Trinh Tran Dinh , Noi Nguyen Van , Tuan Bui Anh
Published: January 2024

Graphene aerogel (GA) was synthesized by chemical reduction of graphene oxide (GO) using ethylene diamine as a reducing agent, which was then followed by a freeze-drying process. The morphology and surface properties of GA, GO samples were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDX), and Brunauer-Emmett-Teller (BET). GA was then used to study the adsorption process of tetracycline (TC) in aqueous solutions. Different parameters influencing the adsorption efficiency of GA such as pH, adsorbent load, initial concentration of TC, contact time were investigated. The results showed that when GO was transformed to GA, the XRD characteristic peak at about 10.8˚ was shifted to broad peaks at 26˚ and 43˚, implying that the crystalline structure of GO was converted to GA which contained a large percent of amorphous structure and a smaller crystalline structure formed by stacking layers of graphene. The C/O ratio in GA sample was significantly increased compared to GO samples (6.5/1 compared to 1.38/1), suggesting that oxygen-containing functional groups (-OH, -C=O, -O-…) in GO were drastically reduced. The optimal conditions for the adsorption of TC were 10 mg L-1 TC solution, pH 7.0 at 75 min, 0.1 g L-1 of adsorbent, and at 30 °C. The adsorption process was better described by Langmuir isotherm model (R2=0.9938) compared to Freundlich one (R2=0.1302). The maximum adsorption capacity (Qmax) of GA calculated by the Langmuir model was 107.5 mg g-1, significantly higher than other common adsorbents. GA presented a stable and promising adsorbent for TC removal in water.
FLAVONOIDS FROM THE RHIZOMES OF BLACK GINGER KAEMPFERIA PARVIFLORA WALL. EX BAKER, ZINGIBERACEAE
Authors: Loan Ly Tu , Hue Phan Thi Ai , Thanh Ma Chi
Published: January 2024

Kaempferia parviflora Wall. ex Baker, Zingiberaeceae has been used in traditional medicine in Vietnam for the treatment of inflammation, abdominal pain, indigestion, menstrual cramps, fatigue. From the n-hexane fraction of the rhizomes of Kaempferia parviflora, six compounds were isolated and determined as 5-hydroxy-3,7-dimethoxyflavone (1), 5,7-dimethoxy chrysin (2), 5-hydroxy-7-methoxyflavone (3), 5-hydroxy-3,4',7-trimethoxyflavone (4), 4',5,7-trimethoxyflavone (5), and 3,4',5,7-tetramethoxyflavone (6). The structures of 1-6 were elucidated by extensive spectroscopic methods (MS, 1D, and 2D NMR)
The Effect of Sulfentrazone and Glyphosate Herbicides to Control Eleusine Indica L. a Resistant weed to Herbicide
Authors: Ha Cam Hong , Ardi Ardi , Dwipa Indra
Published: January 2024

Weed Eleusine indica L. was reported to have been difficult to control using glyphosate in Oil palm plantation during the time. Sulfentrazone was used as an alternative herbicide for the management of resistant weeds. The aim of this study was to determine the effects of two active ingredients Glyphosate and Sulfentrazone on weed Eleusine indica L. resistant to herbicide. The study was conducted using Completely Randomly Designed (CRD) with 14 treatments and 3 replications. 14 treatments consisted of single herbicide Glyphosate, which was applied at field rate 2 l/ha, Sulfentrazone was sprayed at the numerous dose of 500, 750, 1000, and 1250 ml/ha, and the mixture of Glyphosate and sulfentrazone at the dose of 500 ml/ha + 2 l/ha and 750 ml/ha + 2 l/ha, respectively. The research was conducted at the Greenhouse of the Faculty of Agriculture, Andalas University, Padang, from August to December, 2021. The results showed that there were significantly effect when used in combination of herbicides Glyphosate and Sulfentrazone, showed 100% of mortality weed after 3 week application. For a single active ingredient, Glyphosate controlled eficiently weed at the 4-leaf stage, Sulfentrazone had same impact on managing weed on the 4 and 6-leaf stage, both caused 100% weed dead. However, weed Eleusine indica L. was treated with Glyphosate still survived on 6 and 8 leaves weeds. Similar to Glyphosate, Sulfentrazone could not completely control resistant weeds at the 8-leaf stage. Classification of resistant weed Eleusine indica L. are herbicide-developing resistance 14%, herbicide-resistant 22%, and herbicide-susceptible 64%.
The EFFECTIVITY OF 150 g/L METAMIFOP HERBICIDE TO IDENTIFY AND CONTROL WEEDS IN PADDY FIELD CULTIVATION (Oryza sativa L)
Authors: Hernawati Dewi
Published: January 2024

Weeds are one of the obstacles to the growth of lowland rice cultivation which can reduce the quantity of rice yields so that weeds need to be controlled. This study aims to determine the effect of metamifop 150 g/L herbicide to control weeds in lowland rice cultivation. The experiment was carried out on paddy rice cultivation land in Langansari Village, Tarogong Kaler Cipanas District, Garut Regency, West Java, from November 2022 to February 2023. The experiment used a Randomized Block Design (RBD) with six treatments and four replications. The experiment consisted of four treatments with the active ingredient metamifop 150 g/L at a dose of A: 5.4 ml, B: 7.2 ml, C: 9.0 ml, D: 10.80 ml, E: manual weeding treatment and F : control treatment with no weed control. The results showed that the application of the herbicide with the active ingredient metamifop 150 g/L at a dose of D: 10.80 ml was able to suppress weed growth but the results were not significantly different from the dose of 5.4 ml which was the lowest dose to reduce weed resistance and plant residues so that dose A : 5.4 ml able to suppress the growth of weeds Echinochloa crusgalli, Monochoria vaginalis, Cyperus rotundus, Spenochlea zeylanica, Panicum repens, Cyperus difformis and total weeds.
Kamu Hastanelerinin Finansal Performansının Oran Analizi ile Değerlendirilmesi: Türkiye Örneği
Authors: BABACAN Ahmet , AKCA Nesrin
Published: January 2024

Bu çalışma ile Sağlık Bakanlığı’na bağlı kamu hastanelerinin 2016-2020 yılları arasındaki finansal performansı oran analizi yöntemi ile ölçülerek, analiz sonuçlarına göre işletmenin finansal yapısının değerlendirmeye tabi tutulması ve bu sayede hastane yöneticilerinin finansal karar almalarına yardımcı olunması amaçlanmıştır. Yapılan çalışmada kamu hastanelerinin finansal kaynaklarının ne derece etkin ve verimli kullanıldığı ölçülmüştür. Çalışmada, 2016-2020 yıllarına ait bilanço ve gelir tablolarından

elde edilen veriler, oran analizi yöntemi ile analiz edilmiş ve yıllar içerisindeki değişimler dikkate alınarak hastanelerin finansal performanslarının ne şekilde gerçekleştiği tespit edilmiştir. Yapılan analizler sonucunda kamu hastanelerinin likidite açısından stoklarının yüksek olduğu, devir hızlarının genel olarak iyi olduğu, hastanelerin kamu hastaneleri olması nedeniyle kârlılık oranlarının düşük kaldığı saptanmıştır. Hastanelerin finansmanında kısa vadeli borçların yer aldığı ve Sosyal Güvenlik Kurumu’nun en büyük

gelir kaynağı olduğu tespit edilmiştir. Çalışma sonuçlarının, hastane yöneticilerine finansal kaynakların etkin ve verimli kullanılmasına yönelik yol gösterici bir rehber olacağı düşünülmektedir. Ayrıca; detaylı maliyet analizleri ile hastanelerin finansal performansları önemli ölçüde iyileşecek ve bu sayede elde edilecek tasarruflar daha etkin kullanılabilecektir.
Flexural Strength of Glass Fiber Post Following Conditioning with Various Chemical Solutions Running Title: Flexural Strength of Fiber Post with Different Chemical Treatments
Authors: A. Ahmad Zena , M Nayif Maan , A. Fathi Ula
Published: January 2024

The aim of this study was to assess various chemical solutions on the surfaces of glass fiber post could affect its flexural strength. A total of 80 Glass Fiber posts were divided into eight groups (n=10) based on surface treatment, untreated surface (control), 10% hydrofluoric acid (HF) for 1 minutes, 10% HF for 2 min, 24% hydrogen peroxide (H2O2) for 4 min, 24% H2O2 for 10 min, 35% H2O2 for 4 min, 35% H2O2 for 10 min, and chloroform solution for 1 hour. Fiber posts were immersed in the solutions for the required amount of time and then rinsed and dried. Fiber posts were loaded in three-point bending test using a mechanical testing machine, data recorded and Flexural strength (σ) was measured. Statistical analysis revealed that the highest value of flexural strength was shown in the group treated with 24% H2O2for 4minfollowed by Chloroform group, so they have no significant effect on flexural strength. While the least value was shown in group treated with10% HF for 2min.Treatment with HF significantly decrease flexural strength for both application times. Treatment with H2O2 showed significant decrease only in group treated with 35% H2O2 for 10 min. It was concluded that strong acid etching of HF and long application time of higher concentration of H2O2 had adverse effect on fiber post flexural strength.
Genetic Box: Character, Validity, Practicality, and Effectiveness as A Learning Media
Authors: Susiani  , Jamilah  , Khalifah Mustami  , Syahriani  , Azmi Fathin Eka Nugraha
Published: January 2024

This study employed research and development (R & D) with a four-dimensional development model that includes four stages: define, design, develop, and disseminate. This research aimed to determine the characteristics, level of validity, practicality, and effectiveness of genetic box learning media for class XII genetic material at SMA Negeri 22 Bone. The genetics box learning media is a product that is being developed and will be tested through validity, practicality, and effectiveness tests. The research subjects were 29 class XII students at SMA Negeri 22 Bone. The instruments in this study included student and educator response questionnaires to obtain product practicality data, media characteristic sheets to obtain the characteristics of the developed genetics box media, and learning achievement tests to obtain product effectiveness data. According to the findings of this study, the media have an appealing appearance, are clear and neat, and use appealing color combinations. Genetic box media is easy to operate and does not require electronic facilities or equipment to use. In addition, the genetics box has value in helping students understand the material and can provide a comprehensive learning experience. The genetics box media also has quite good tool durability because it is made of hard materials such as wood and boards. The genetics box media formulates learning objectives and refers to material items that support the achievement of those objectives. In addition, the genetics box learning media for class XII genetic material at SMA Negeri 22 Bone has a validity level of expert validity and a material expert value of 3.72 with a very valid category. The response of students and educators to the level of practicality is worth a total of 3.52 in the positive category. The learning achievement test of students using the genetics box learning media on genetic material for class XII at SMAN 22 Bone is in the effective category because it reaches 100%, so the genetics box learning media for class XII genetic material at SMAN 22 Bone is feasible to use because it meets valid, practical, and effective criteria.