bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictors of Adherence and Asthma Control in Two Federal Teaching Hospitals in Nigeria
Authors: Amorha Chinwendu Amorha , Okonta Mathew J , Ukwe Chinwe V
Published: June 2022

Asthma is a common chronic disease in developing countries. The main objective of the study was to provide insights into adherence and asthma control predictors in two federal teaching hospitals in Nigeria, using validated instruments. For the data analysis, the level of statistical significance was set as p < 0.05. Seventy-eight patients with asthma provided consent for study participation. Every time domestic fuel was utilized at home, asthma control decreased by 1.246 units, p = 0.029. Every time an asthma patient utilized one of the hospitals which did not have a separate Asthma Clinic, adherence decreased by 1.483 units, p < 0.001. The study reveals the need for patients with asthma to minimize the use of domestic fuel. Renewable energy sources could be considered. A separate Asthma Clinic can provide ample time for asthma reviews.
Dhaka Univ. J. Pharm. Sci. 21(1): 45-51, 2022 (June)
Qualitative Assessment of a Customized Anti-hepatic Herbal Formulation in Bangladesh
Authors: Rahman Md Hafizur , Rokeya Begum , Mosihuzzaman Mohammed , Haque Khan Md Shahinul
Published: June 2022

Qualitative assessment of herbal formulations is used in pre-health care of many diseases. The potency, composition and safety of herbal formulation are serious concerns in Bangladesh. Therefore, the aim of the present study was to evaluate the qualitative assessment of a customized anti-hepatic herbal formulation in Bangladesh. Isolation of compounds, toxic metals analysis, phytochemical screening, microbial test and determination of SGPT and SGOT level of hepatic model rats were focused in this study. The phytochemical screening revealed the presence of phenol, saponins and tannins. In chemical study, four known compounds were isolated from the formulation (Sodium benzoate, methyl-4-hydroxybenzoate, 4-hyroxybenzaldehyde and 4-hydroxy- 3-methoxybenzaldehyde). The results of microbial purity and toxic metals analysis were in favorable limit although the levels of SGOT and SGPT were raised non-significantly. So, based on the study it has been concluded that quality assessment is urgently required for this type of customized herbal formulations.
Dhaka Univ. J. Pharm. Sci. 21(1): 59-67, 2022 (June)
Development and Optimization of RP-UHPLC Method for Mesalamine Through QbD Approach
Authors: Shill Diponkor Kumar , Kumar Uttom , Al Hossain ASM Monjur , Rahman Md Rezowanur , Shamsur Rouf Abu Shara
Published: June 2022

The current study aimed at developing and optimizing a prompt, simple and efficient RP-UHPLC method based on Quality by Design (QbD) for analyzing mesalamine. Experimental design for developing the method was performed capitalizing a 32 full factorial design in Design Expert® software (Version 12, Stat-Ease Inc., USA) where the percentage of methanol in the mobile phase and flow rate of the mobile phase were considered as independent factors and studied at three levels. Retention time, tailing factor and theoretical plate count were recorded as responses to the experiment. Mesalamine was analyzed using a reversed-phase C18 column (5μm, 150 ×4.6 mm) supported by a photodiode array plus (PDA+) detector with detection at 214 nm. The optimized method involved the use of a mobile phase of pH=7.4 phosphate buffer: methanol (63.5: 36.5, v/v) and a flow rate of 1.1 ml/min. Responses recorded during experimentation exhibited an error of -0.24%, 0.376% and -0.659% from predicted values of retention time, tailing factor and theoretical plate count, respectively. Experimental models adopted for the development of the method were found statistically significant (p-value <0.05). According to ICH Q2 (R1) guidelines, the method was also found to be robust, highly sensitive, specific, accurate, precise and linear.
Dhaka Univ. J. Pharm. Sci. 21(1): 77-84, 2022 (June)
A generalized two-sweep shift splitting method
for non-Hermitian positive definite linear systems
Authors:   School of Mathematics, Yunnan Normal University, Kunmin 650500, Yunnan, P.R. China, Wu Shi-Liang , Li Cui-Xia ,   School of Mathematics, Yunnan Normal University, Kunmin 650500, Yunnan, P.R. China
Published: June 2022

In this paper, based on the shift splitting of the
coefficient matrix, a generalized two-sweep shift splitting (GTSS)
method is introduced to solve the non-Hermitian positive definite
linear systems. Theoretical analysis shows that the GTSS method is
convergent to the unique solution of the linear systems under a
loose restriction on the iteration parameter. Numerical experiments
are reported to the efficiency of the GTSS method.
PERBANDINGAN PEMBELAJARAN MATEMATIKA SECARA DARING DAN PEMBELAJARAN MATEMATIKA SECARA LURING TERHADAP HASIL BELAJAR MATEMATIKA SISWA KELAS VII MTS GUPPI PAGAR ALAM
Authors: Efendy Arieska
Published: June 2022

Education is a form of effort that is carried out consciously and intentionally in order to change behavior and mature human beings, both individually and in groups through learning and training. The problem facing the world of education today is the weakness of the learning process. Many parties did not think that the corona virus (Covid-19) would become a pandemic that spread throughout the world, including Indonesia. The conditions faced today are indeed not easy for the world of education. The learning process is not as free as before where there is a lot of interaction between students and students, students and teachers. The purpose of this study was to determine the comparison of online mathematics learning and offline mathematics learning on the mathematics learning outcomes of seventh grade students of MTs Guppi Pagar Alam. This research is a type of quantitative approach research. This research is quantitative in nature, namely the data obtained are analyzed by statistical formulas to obtain conclusions. Based on the results of research and discussion, it can be concluded that offline mathematics learning can improve student learning outcomes for class VII MTs GUPPI Pagar Alam. This can be seen from the average value of student learning outcomes using offline learning is 70.29 while the average value of student learning outcomes without using online mathematics learning is 60.43.Keywords: Mathematics, Offline Learning, Learning Outcomes
Perbandingan Algoritma Pembelajaran Mesin untuk Klasifikasi Warna Kulit Berdasarkan Warna Piksel Citra
Authors: Ridla Muhammad Ali
Published: June 2022

Klasifikasi warna citra digital untuk mendeteksi warna kulit atau bukan kulit merupakan hal yang sangat penting dalam dunia Computer Vision. Hal ini sangat membantu berbagai aplikasi dalam kehidupan nyata, seperti aplikasi deteksi wajah, gerakan tangan, sistem keamanan, deteksi penyakit kulit, pemblokiran konten dewasa, dan lain sebagainya. Warna merupakan komponen yang paling utama dalam hal mendeteksi warna kulit pada citra, oleh karena itu pada penelitian ini akan dilakukan eksperimen klasifikasi warna kulit pada piksel sebuah citra menggunakan ruang warna yang berbeda beda diantaranya, RGB, HSV, YCbCr, dan SCgCr dengan memanfaatkan algoritma pembelajaran mesin, yaitu KNN, Naïve Bayes, dan Random Forest. Pada penelitian ini, data yang digunakan merupakan data public Skin Segmented yang bersumber dari UCI dengan ruang warna RGB dan transformasi ke ruang warna lainnya, hasil klasifikasi yang dilakukan ternyata menghasilkan performa yang sangat baik, untuk algoritma KNN dan Random Forest selalu mendapatkan tingkat akurasi di atas 95% di semua ruang warna tersebut.
Variasi Besar Arus Listrik dan Ketebalan Pelat pada Pengelasan SMAW Terhadap Distorsi Angular Sambungan T Baja ST37
Authors: Fajarwati Meditama Ratna , Chandra Permadi Luchyto , Khoufi Asshidiqi Faisol
Published: June 2022

Distorsi las T baja ST37 dengan SMAW berpengaruh pada kualitas, ketelitian, ukuran, dan dimensi. Distorsi dipengaruhi oleh panas lasa dan tebal pelat. Penelitian bertujuan menganalisis variasi arus listrik (I) dan tebal pelat (h) terhadap distorsi angular T Baja ST 37. Metode yang digunakan berupa kajian eksperimental pre test dan post test untuk memperoleh data yang relevan dengan hipotesis yang akan diuji. Tujuan penelitian (1) Menemukan pengaruh variasi besar arus listrik (80 A, 100 A, dan 120 A) pada pengelasan SMAW terhadap distorsi angular sambungan T baja St 37, (2) Menemukan pengaruh variasi ketebalan pelat (3 mm, 4 mm, dan 5 mm) pada pengelasan SMAW terhadap distorsi angular sambungan T baja St 37, (3) Menemukan pengaruh yang signifikan antara variasi arus listrik (80 A, 100 A, 120 A) dan ketebalan pelat (3 mm, 4 mm, 5 mm). Penelitian ini tergolong jenis penelitian eksperimental dengan rancangan factorial 2 x 3 x 3. Hasil penelitian menemukan bahwa besar arus listrik dan ketebalan pelat mempengaruhi terjadinya distorsi angular pada sambungan T baja St 37, diantaranya: (1) Arus listrik 120 A menghasilkan mean distorsi angular tertinggi yaitu 2,014 mm dan arus listrik 80 A menghasilkan mean distorsi angular terendah yaitu 0,558 mm, (2) Ketebalan pelat 3 mm menghasilkan mean distorsi angular tertinggi 2,014 mm dan ketebalan pelat 5 mm menghasilkan mean distorsi angular terendah 0,558 mm, (3) Pada arus listrik 120 A dengan ketebalan pelat 3 mm, pada pengelasan sambungan T paling tinggi menyebabkan distorsi angular daripada arus listrik dan ketebalan Pelat yang lain dengan nilai rerata sebesar 2,014 mm.
EMPIRICAL INVESTIGATION OF VIDEO SURVEILLANCE SYSTEM ADOPTION IN NIGERIA
Authors:   National Board for Education, Bello Oladipupo
Published: June 2022

—The acceptance of video surveillance systems at homes, offices and business enterprises nowadays to reduce incidences of theft, burglaries, sexual offences and other forms of crimes is increasing. This study investigated the factors that influence adoption of video surveillance systems in Nigeria. Based on Rogers’ diffusion of innovation model, the effect of relative advantage, compatibility, complexity, trialability and observability on adoption of video surveillance systems was examined. Structural equation model analysis of the collected data shows that relative advantage, compatibility, trialability and observability significantly influence adoption of video surveillance systems. However, the results indicate that adoption of video surveillance systems is not influenced significantly by complexity. Thus, complexity of video surveillance systems is perceived as a barrier to adoption of this technological innovation among Nigerians.
ICTs INCLUSION FOR BUSINESS GROWTH IN THE DIGITAL AGE: THE SOCIAL MEDIA PERSPECTIVE
Authors:   Federal University of Agriculture, T. Johnson Femi , A. Agholor Sunday ,   Federal College of Education, T. Bukola Adebiyi , Ezinne Ihekwoaba ,   Federal College of Education
Published: June 2022

The organized effort and activities involving two or more individuals with the sole aim of exchanging goods and services either for profit or satisfaction of needs has been in existence about some centuries of years ago through the introduction of the trade by barter system of trading. Over the years, this and other traditionally metamorphosed mode of business transaction are faced with numerous challenges, thus hindering business growth despite the changes in the mode and manner adopted by organizations towards performing business transactions. However, the 21st century has thus provided a better, safer, improved and more secured means of engaging business transactions for successful business growth with the invention of Information Communication Technology (ICTs). In this sense, the main objective of this paper is to share and present the possibilities of improving marketing strategies with social media advert analytics using new and emerging ICTs in supporting and ensuring successful business growth.
EVALUATION OF A SUITABLE THIN LAYER MODEL FOR DRYING OF PRETREATED COCOYAM SLICES USING A CONVECTIVE HOT AIR DRYER
Authors:   University of Uyo, J. Etti Christopher , M. Nkem Owoidoho ,   University of Uyo
Published: June 2022

This work evaluated the thin layer drying kinetics of pretreated cocoyam slices (Xanthosoma sagittifolium) in a convective hot air dryer. Seven thin layer theoretical and empirical models widely used in describing the drying behaviour of agricultural products were fitted to the experimental data in order to select the appropriate model for predicting the drying kinetics of cocoyam (Xanthosoma sagittifolium). The Page model showed the best fit under certain drying conditions based on the coefficient of determination (R 2 ) and sum of squares error (SSE). Comparison was made between the experimental and model predicted moisture ratio by non-linear regression analysis. Furthermore, the effect of drying temperature and pretreatment on the best model constants was evaluated. Consequently, the page model showed an excellent fit with the experimental data (R 2 > 0.99 and SSE < 0.0010) for the drying temperatures of 50, 60 and 70 °C at different sample pretreatments; untreated (raw), water soaked and brine soaked respectively. Thus, page model can adequately predict the drying kinetics of cocoyam under pretreatment conditions.
A COMPUTERIZED KNOWLEDGE SHARING FRAMEWORK FOR THE SUPPLY CHAIN DEVELOPMENT PHASES
Authors:   Charles Darwin University, Baydoun Ali , Danach Kassem ,   Islamic University of Lebanon, Al-Haj Hassan Jomana ,   Islamic University of Lebanon
Published: June 2022

— although the extant literature has addressed knowledge sharing in various forms, one question remains unresolved, arising from the need for an automated process for sharing knowledge in the Supply Chain (SC). A proposal of a computerized knowledge sharing framework for the SC will impact the SC’s performance and productivity. This paper aims to review and analyze the literature on knowledge sharing strategies and then suggest an automated knowledge sharing framework for the SC. First, to develop the proposed framework, we thoroughly reviewed the literature on SC knowledge sharing processes. This review helps us identify how organizations share and manage knowledge during the development process of their SCs. Then, we proposed a computerized knowledge sharing framework for the SC. Accordingly, we suggested that the proposed knowledge sharing framework is unique among the literature strategies, because it automates the knowledge sharing process in the SC, adds value to existing research, and could be adopted by SC decision-making as a knowledge framework to increase the efficiency of sharing, and managing knowledge in the SC phase.
KNOWLEDGE BASE CLOUD FRAMEWORK FOR EFFECTIVE KNOWLEDGE RETENTION IN SOFTWARE SUPPLY CHAIN
Authors:   Charles Darwin University, Baydoun Ali , Ahmad Fatima ,   Hamad Bin Khalifa University
Published: June 2022

— Most researches focus and suggest Database and Data Warehouses to manage and manipulate organizational knowledge, although both are more suited for running data and information. Hence, they lack the basic constructs required to manipulate knowledge. This research introduces a framework for a new type of Knowledge Base (KB), which refers to as a Software Service Supply Chain Knowledge Base CLOUD (SSSC KB CLOUD) framework. SSSC KB CLOUD framework provides and explores the infrastructure for manipulating knowledge during the developmental process of Software Service Supply Chain (SSSC). Also, it explores the main technical components of the SSSC KB CLOUD and shows how these components integrate and work together to achieve the main aims of SSSC KB CLOUD. The proposed framework shows the life cycle of knowledge in SSSC. It highlights the source of knowledge in SSSC and how it passes the SSSC KM process for sorting and refining. Then, it suggests a SSSC KB CLOUD framework to store and manipulate this knowledge. Finally, it provides the SSSC experts with an interface to access and retrieve knowledge from the SSSC KB CLOUD. The SSSC KB CLOUD consists of four components: Knowledge Cloud Management System (KCMS), Prior Projects Knowledge Marts (PPKM), Experts’ Base (EB), and SSSC Group Formation CLOUD. KCMS provides a management system of SSSC KB CLOUD, while, PPKM is considered a knowledge repository of the knowledge captured during the development of projects, it also stores and holds all the retained SSSC knowledge. Moreover, EB stores and holds the SSSC experts’ details, including the area of expertise, experience, education, etc. Thus, SSSC KB CLOUD holds the experts’ details and records in its EB. Given the previously mentioned components, the SSSC KB CLOUD framework suggests SSSC group formation CLOUD, a new functionality of forming a new SSSC experts’ group to work and complete the new client project.
INTERNET OF THINGS (IOT): AN OVERVIEW ON RESEARCH CHALLENGES AND FUTURE APPLICATIONS
Authors:   Sinhgad College Of Science, Bhimrao Shendge Antima
Published: June 2022

This paper focus on future applications of Internet of Things. The Internet of things (IoT) describes the network of physical objects—“things”—that are embedded with sensors, software, and other technologies for the purpose of connecting and exchanging data with other devices and systems over the Internet. With the Internet of Things (IoT) gradually evolving as the subsequent phase of the evolution of the Internet, it becomes crucial to recognize the various potential domains for application of IoT, and the research challenges that are associated with these applications. Ranging from smart cities, to health care, smart agriculture, logistics and retail, to even smart living and smart environments IoT is expected to infiltrate into virtually all aspects of daily life. Even though the current IoT enabling technologies have greatly improved in the recent years, there are still numerous problems that require attention. Since the IoT concept ensues from heterogeneous technologies, many research challenges are bound to arise. The fact that IoT is so expansive and affects practically all areas of our lives, makes it a significant research topic for studies in various related fields such as information technology and computer science. Thus, IoT is paving the way for new dimensions of research to be carried out. This paper presents the recent development of IoT technologies and discusses future applications and research challenges.
MOBILE CLINICS ROUTING IN RESPONSE TO COVID-19 OUTBREAK: AN INTELLIGENT HYPERHEURISTIC APPROACH
Authors:   Islamic University of Lebanon, Danach Kassem , Baydoun Ali ,   Charles Darwin University, Al-Haj Hassan Jomana ,   Islamic University of Lebanon, Tarhini Abbas ,   Lebanese American University
Published: June 2022

— In March 2020, the World Health Organization (WHO) announced the COIVD-19 as a global pandemic that caused thousands of deaths and brought the world to a standstill with a huge economic burden [1]. Health is an essential factor for sustaining a better life in a better world. Today, for different reasons, several districts in our countries would be deprived from the needed health support and thus, in such cases, we need to deliver health care to those regions. Despite its considerable cost, the mobile clinic remains one of the good solutions to deliver health care to critical areas in our countries. A recognized problem in this domain is minimizing the cost of mobile clinics route in a way that the number of served patients is maximized. This problem is known as the mobile clinics routing problem (MCRP). The purpose of this paper is to present a novel approach that, within the given limited resources, it minimizes the cost and the traveling distance of mobile clinics while maximizing the number of served patients as per priorities assigned according to the patients’ medical status. This paper implements and tests an intelligent variable neighbourhood search algorithm for MCRP
EFEKTIVITAS KULIT BAWANG MERAH (Allium ascalonicum) TERHADAP PERTUMBUHAN PAKCOY (Brassica rapa)
Authors: Putri Yosi Dwi Ananda , Kurniasih Surti , Munarti .
Published: June 2022

Mustard production in indonesia from 2017 to 2019 had been decreasing year by year, while market demanded for vegetable production had increased.  On the other handed, shallot production in 2017 to 2019 increased, resulting in an abundance of shallot waste.  Natural resources in the form of organic materials and organic waste that exist around farmers and the community in general could been made as organic fertilizer.  Based on this, it was necessary to studied the effectiveness of liquid organic fertilizer (poc) of onion peel waste on the growth of pakcoy plants.  The purpose of this studied was to studied the effect of onion peel waste on the growth of pakcoy.  This studied used an experimental method with a completely randomized design (crd) consisting of 5 treatments and each treatment consisted of 5 replications, so the total number of experimental units was 25 experimental units.  The concentration given to each treatment was p0 (0%), p1 ( 20%), p2 (40%), p3 (60%) and p4 (80%).  Growth parameters observed was number of left, plant height and wet weight.  The results showed that the administration of red onion peel waste had a significant effect on the growth of pakcoy on the three parameters observed.  The optimal treatment for the number of left was p1(20%), plant height p3 (60%) and wet weight p1(20%) Keywords: Liquid Organic Fertilizer, Pakcoy, Shallots
UJI AKTIVITAS EKSTRAK ETANOL KOMBINASI DAUN PANDAN WANGI DAN DAUN JAMBU BIJI TERHADAP Shigella dysenteriae
Authors: Komala Oom , Abd.Nf Durrotun Nafisah , Utami Novi Fajar
Published: June 2022

Dysentery can be treated using Pandanus amarylifolius leaves and Psidium guajava leaves. This study aimed to determine the activity of the combination of 96% ethanol extract of P. amarylifolius leaves and P. guajava leaves in inhibiting the growth of Shigella dysenteriae bacteria. Methods. Extraction of P. amarylifolius leaves and P. guajava leaves respectively by using the maceration method with 96% ethanol solvent. For the combination treatment, each of these extracts was combined. Each extract obtained was tested for minimum inhibitory concentration (MIC). The MIC value of P. amarylifolius leaf extract was obtained at a concentration of 30% and P. guajava leaf extract was obtained at a concentration of 40%. Inhibitory width test (IWT) by disc diffusion method was carried out on single extracts and combination extracts, with treatment concentrations of 30% single extract of P. amarylifolius leaf (K1), 40% single extract of P. guajava leaf (K2), combination 1 (P. amarylifolius leaf). 30%+ P. guajava leaf 40%) (K3), combination 2 (35% P. amarylifolius leaf + 40% P. guajava leaf) (K4), combination 3 (40% P. amarylifolius leaf + 40% P. guajava leaf) (K5). The width of the inhibition of the research results of the treatment against S. dysenteriae were analyzed using a completely randomized design and Duncan's test. The results showed that the combination of P. amarylifolius leaf extract and P. guajava leaf was more effective in inhibiting the growth of S. dysenteriae bacteria. The combination of P. amarylifolius leaf extract and P. guajava leaf extract that was most effective in inhibiting the growth of S. dysenteriae bacteria was combination 3 (40% P. amarylifolius leaf extract + 40% P. guajava leaf extract) with an average inhibitory width of 5.625 mm. Keywords: Combination, P. amarylifolius Leaves, P.guajava Leaves, S. dysenteriae
KERAGAMAN TUMBUHAN INVASIF DI HUTAN PENELITIAN DRAMAGA BOGOR
Authors: Priyono Purwohadi Purbo , Ismanto . , Susilo Adi
Published: June 2022

Invasive Plant is species that dominate an area or places, both are native species and non-native species. Invasive Plants is one of the crucial problems in ecosystem management because it is a major component of global environmental change, threats to biodiversity and local species, as well as, causes of changes in nutrient cycles, fire cycles, hydrological cycles, and energy balance. The purpose of this study is to prove that plants far from the road are more commonly invaded by invasive species and that physical and biological factors affect the growth of invasive species. The research was conducted at the Dramaga Research Forest, Bogor from June 2020 to August 2020. This study used a vegetation analysis method, which is using nesting plots that have a size of 2 x 2 m for seedlings, 5 x 5 m for saplings, 10 x 10 m for poles, and 20 x 20 m for trees. Plots were made in two locations, close to the road and far from the road. The location close to the road was 5 - 10 meters, and far from the road was 70 - 80 meters The total plots made in this study were 16 plots in each size. The results showed that the highest diversity was found at the level of seedlings, namely medium status (2.00-3.00) according to the Shannon-Wiener index. The results showed that the statistical analysis of the diversity of weeds in the Dramaga Research Forest were not significantly different, between plants close to the road and plants far from the road. This is causing by physical factors that are not significantly different based on statistical tests. The growth of invasive plant species is influenced by several factors, such as light intensity, temperature, humidity, and soil pH. Keywords: Dramaga Research Forest Bogor, Invasive species, Vegetation analysis
PENGEMBANGAN PANGKALAN DATA KERAGAMAN SPESIES ANURA DI CAGAR ALAM TELAGA WARNA
Authors: Prihatini Wahyu , Rahayu Sata Yoshida Sri , Al-Adhari Nida Masyidatul Madyan
Published: June 2022

The Telaga Wama Natural Reserve (CATWA) at Bogor Regency, West Java Province is a biodiversity conservation area, however, the changed of some of the area's functions into a Nature Tourism Park can affect the quality of its ecosystem. One approach to evaluate ecosystem quality is through the analysis of Anura species diversity. The continuity of the Anuras eggs and larvae is influenced by the presence of pollutants in the waters. The availability of Anura species diversity database can be an indication of the aquatic ecosystem quality at CATWA. This research was conducted using the Visual Encounter Survey method at five sampling locations in CATWA, namely river, lake, swamp, forest pond, and waterfall. Observations of tadpoles were carried out twice a week, for four weeks, accompanied by physical-chemical measurements of the waters, namely DO, BOD, COD, temperature, pH, depth, and turbidity. The Anura diversity database is made up of a time series, combining of this study result, and previous reports. This study had identified 10 species of tadpoles from six Anura families, namely Dicroglossidae, Megophyridae, Ranidae, Bufonidae, Rhachoporidae and Microhylidae. The level of species diversity is moderate (H'=2.29). Turbidity and water temperature have the highest correlation with species diversity. The water quality in CATWA was relatively good, and able to support the life of Anura. This is also evidenced by the presence of species representatives from all Anura families in Java Island.
PENENTUAN LOKASI BASIS DAN NON BASIS PENYEBARAN VIRUS CORONA (COVID-19) MENGGUNAKAN METODE LOCATION QUOTIENT (LQ)
Authors: Iswanto Toto , Widyastiti Maya
Published: June 2022

The corona virus pandemic that has hit the entire world is a threat to the order of people’s lives in all field so it must be solved quickly. This study aims to determine the location of the Basic and non-Basic of the spread of corona virus in Lubuk Besar district, Province of Bangka Belitung Island. Data used is this study are the number of population and the number of COVID-19 cases in Lubuk Besar district, Bangka Belitung Province. This research is a descriptive type of research with a quantitative approach using the Location Quotient Method. The results showed that in January 2021 there are 4 villages that became the basis location for the spread of the corona virus, i.e. Kulur Village with LQ value is 1.634581, Kulur Ilir Village with LQ value  is 1.618289, Lubuk Besar Village with LQ value is 1.914148, and Perlang Village with LQ value is 1.412130, and the other villages are non-basic. In February 2021 the villages that became the basis are Kulur Ilir Village with LQ value is 1.182939, Perlang Village with LQ value is 1.376094, and Trubus Village with LQ value is 2.996931, and the other villages are non-basic location. In March 2021, Perlang Village with LQ value is 1.184505 and Trubus Village with LQ value is 5.600585 became the basis for the spread of the corona virus, and the other villages are non-basic location.
EFFECTS OF YEAST WEIGHT AND STARTER VOLUME ON THE PERCENTAGE KEPOK BANANA BASED BIOETHANOL
Authors: Cantika Kurnia Dewi Budi , Nabila Anisa Sinta , Sucisatryani Difa Afiyah
Published: June 2022

The low availability of energy resources is in line with the increasing human need for these resources, such as fossil fuels which are increasingly expensive because they are difficult to obtain right. Bioethanol is an environmentally friendly liquid produced from the glucose fermentation process from carbohydrate sources of natural raw materials with the help of microorganisms in baker's yeast. The focus of the research is on the waste of kepok banana peels because it has a high starch content of 18.5%. In addition, kepok banana peel waste is easy to obtain and has not been widely used by the community. This study aims to determine the effect of yeast weight and starter volume in the manufacture of bioethanol and the quality of the bioethanol produced by comparing the levels with the reference levels of bioethanol as an alternative fuel. The bioethanol obtained from the starch of the kepok banana peel has gone through a fermentation process with Saccharomyces cerevisiae and refined into pure bioethanol. Based on the related literature review, it shows that the greater the weight of yeast and the volume of starter used in the manufacture of kepok banana peel bioethanol influences the yield of bioethanol content which also increases so that it affects the quality of the bioethanol produced. However, the level of bioethanol that is obtained has not reached the standard range of SNI 7390:2012 with a minimum level of bioethanol as a substitute for fuel being 94.0-95.5%. Thus, bioethanol cannot be used as a substitute for fossil fuels and further research is needed with the use of the optimum amount of yeast and starter volume and re-purification.
ANALISIS KECACATAN PRODUKSI GALLON DENGAN METODE DMAIC SIX SIGMA SEBAGAI UPAYA PENGENDALIAN KECACATAN PRODUKSI Studi Kasus: PT PRIMADAYA PLASTISINDO
Authors: Amelia Rika , Kamila Isti
Published: June 2022

Defects are products that produced in the production process, the product is not in accordance with the applied quality standards, but economically the product can be repaired by spending certain cost. The cost that incurred must be lower than the selling value after the product is repaired. PT Primadaya Plastisindo is a company engaged in plastic packaging manufacture by using “Blow Moulding” and “Extrusion” with a set of foreign investment (PMA), namely Taiwan, Malaysia and Singapore. It is quite important in the company to analyze defects in gallon products as a result of disability control efforts with the six sigma method with DMAIC approach, those are define, measure, analizy, improve and control. The results showed that sigma level value is 2,625 or in 3 sigma with possible damage is 133,219 for a million production process or 13.3% defect per million opportunities (DPMO). The damage generated in production is categorized into 2 groups namely Process Reject and Non-process Reject respectively 57.1% and 42.9%. However, from the control chart obtained the fact that the number of defects is still within reasonable.Keywords: control, DMAIC, Six sigma.
OPTIMALISASI TOTAL PENDAPATAN DENGAN PENGAPLIKASIAN MODEL PEMROGRAMAN NON LINIER DALAM PENENTUAN HARGA JUAL DAN PERMINTAAN PRODUKSI TEMPE
Authors: Ramdhani Abdurachman , Wijayanti Hagni , Sumarsa Amar
Published: June 2022

HJ tempeh factory in Ciluar Bogor is a company engaged in the tempeh production industry that produces several variants of tempeh products.  Product variants include tempeh of sizes 18 cm x 30 cm, 18 cm x 25 cm, 20 cm x 25 cm, 17 cm x 25 cm, and mendoan tempeh of size 8 cm x 14 cm. The raw materials used for the production of each variant are soybeans and tempeh yeast. Due to limited raw materials to produce these variants, it is important for the company to determine optimum selling price as well as number of demands in seeking to obtain optimum revenue. Non-linear programming is used to determine the selling price and production demand of each tempeh product variant in order to optimize the total revenue. This study recommends the factory to generate daily sale of each tempeh variants as follows: 222 packs of tempeh sized 18 cm x 30 cm at Rp 8,299.00; 111 packs of tempeh sized 18 cm x 25 cm at Rp 5,698.00; 65 packs of tempeh sized 20 cm x 25 cm at Rp 6,826.00; 87 packs of tempeh sized 17 cm x 25 cm at Rp 4,805.00; and 833 packs of mendoan tempeh sized 8 cm x 14 cm at Rp 396.00. By using this scheme, total daily income to be gained is Rp 3,676,612.00.Keywords: tempe product variant, elasticity value, non-linear programming, optimization, determination of selling price.
PENGUJIAN PERTUMBUHAN PRODUKSI MAGGOT MELALUI KOMBINASI SAMPAH RUMAH TANGGA DAN DAUN KERING MENGGUNAKAN RANCANGAN ACAK LENGKAP
Authors: Akbar Muhamad Harpan , Setyaningsih Sri , Virgantari Fitria
Published: June 2022

This study aims to find the best combination of treatment in producing maggot from waste processing combined with dry leaves. The data used is primary data based on a combination of processing household waste and dry leaves by observing the amount of maggot production resulting from 5 treatments and 4 replications. The design used was Completely Randomized Design (CRD). The treatments applied to the shelter that accommodates 10 liters are as follows: Treatment A. household waste 90% dry leaves 10%; Treatment B. household waste 80% dry leaves 20%; Treatment C. household waste 70% dry leaves 30%; Treatment D. household waste 60% dry leaves 40%; Treatment E. household waste 50% dry leaves 50%. The results of the Analysis of Variance (ANOVA) test and further testing with BNJ showed that there were significant differences in the five treatments in producing maggot production. The material that gave the best results in maggot cultivation was found in treatment C with a combination of 70% household waste and 30% dry leaves resulting in the highest average maggot production of 761.25 grams.
EKSTRAK ETANOL BUAH STROBERI (Fragaria x ananassa Duchesne ex Rozier) SEBAGAI INHIBITOR TYROSINASE
Authors: . Widyastuti , Primagara Edo
Published: June 2022

ABSTRAK Manusia mempunyai warna kulit yang berbeda akibat perbedaan jumlah melanin. Proses pembentukan melanin terjadi akibat sejumlah enzim, hormon, oksigen, mineral, serta sinar ultraviolet. Kelebihan jumlah melanin dapat menyebabkan terjadinya hiperpigmentasi yang dapat merusak penampilan dari kulit. Penggunaaan bahan pencerah kulit sintetis dapat membahayakan kulit. Penelitian bahan-bahan pencerah kulit dari alam terus dilakukan karena efek samping bahan kimia yang berbahaya bagi kulit. Buah stroberi merupakan suatu antioksidan. Penelitian ini mencoba menguji aktivitas tabir surya dan inhibitor tirosinase secara in vitro dari ekstrak etanol buah stroberi segar dengan menggunakan metode spektrofotometer. Dari penelitian yang dilakukan menunjukkan bahwa ekstrak etanol buah stroberi mengandung metabolit sekunder flavonoid, senyawa fenolik dan saponin. Pada konsentrasi ekstrak 1mg/mL diperoleh kandungan senyawa fenolik total 1755 mg GAE/100 gram ekstrak dengan kapasitas antioksidan sebesar 6,23%. Pada konsentrasi ekstrak 0,6 mg/mL telah didapatkan nilai SPF lebih dari 15 yaitu 26,853. Aktivitas inhibisi tirosinase diperoleh nilai IC50 sebesar 662,096 μg/mL. Ekstrak etanol buah stroberi memiliki potensi sebagai tabir surya dan inhibitor  tirosinase.. ABSTRACT Humans have different skin colors due to different amounts of melanin. The process of melanin formation occurs due to a number of enzymes, hormones, oxygen, minerals, and ultraviolet light. Excess amount of melanin can cause hyperpigmentation which can impair the appearance of the skin. Using synthetic leather brighteners can harm your skin. Research on skin lightening ingredients from nature continued because of the side effects of chemicals that are harmful to the skin. Strawberry fruit is an antioxidant. This study tried to test the activity of sunscreens and tyrosinase inhibitors in vitro from ethanol extracts of fresh strawberries. Research shows that ethanol extracts of strawberries contain secondary metabolites of flavonoids, phenolic compounds, and saponins. In the extract concentration of 1 mg/ml obtained a total phenolic compound of 1755 mg GAE/100 g extract and antioxidant capacity of 6.23%. SPF value of strawberry extract of more than 15 found at a concentration of 0.6 mg/ml extract was 26.853. The tyrosinase enzyme inhibitory activity of ethanol extract of strawberries obtained IC50 values of 662.096 μg/ml. Ethanol extract of strawberry fruit has the potential as a sunscreen and tyrosinase inhibitor.
FORMULASI DAN EVALUASI TABLET HISAP EKSTRAK ETANOL DAUN CINCAU HIJAU (Premna oblongata Miq) SEBAGAI ANTIOKSIDAN
Authors: Najihudin Aji , Nuari Doni Anshar , Caroline Deby , Sriarumtias Framesti Prisma
Published: June 2022

Daun cincau merupakan bagian tanaman yang umumnya digunakan secara tradisional yaitu dijadikan agar-agar, namun cara tradisional tersebut menyebabkan pembuatan dan kegunaan daun cincau menjadi sangat terbatas. Oleh karena itu, perlu adanya pemikiran suatu formulasi untuk mengolah bahan alam menjadi bentuk sediaan yang dapat digunakan secara praktis. Telah dilakukan penelitian tentang tablet hisap dari ekstrak etanol daun cincau hijau (Premna oblongata Miq) sebagai antioksidan. Tujuan penelitian ini adalah membuat tablet hisap ekstrak etanol daun cincau hijau (Premna oblongata Miq) yang memenuhi persyaratan Farmakope Indonesia dan memiliki aktivitas antioksidan. Tablet hisap dibuat dengan menggunakan metode granulasi basah dan dilakukan variasi pengisi manitol-sukrosa dari ketiga formula yaitu pada konsentrasi F1 (75%:25%), FII (50%:50%), dan FIII (25%:75%). Evaluasi tablet hisap meliputi uji organoleptik, keseragaman bobot, keseragaman ukuran, friabilitas, friksibilitas, dan kekerasan. Hasil penelitian menunjukkan bahwa dari ketiga formula tersebut pada formula 2 dan formula 3 yang telah memenuhi persyaratan Farmakope Indonesi Edisi IV. Hasil uji aktivitas antioksidan tablet hisap ekstrak etanol daun cincau hijau bersifat aktif sebagai antioksidan dengan nilai IC50 pada formula I, II, dan III berturut-turut yaitu 52,536 ppm, 59,911 ppm, dan 71,151 ppm, sedangkan IC50 Vitamin C yaitu 8,622 ppm.
FORMULASI DAN UJI AKTIVITAS GEL EKSTRAK DAUN JERUK MANIS (Citrus x aurantium L.) TERHADAP BAKTERI Propionibacterium acnes
Authors: Hindun Siti , Najihudin Aji , Hamdani Siva , Sriarumtias Framesti Frisma , Abdullah Fajar Fauzi
Published: June 2022

Jerawat merupakan penyakit kulit yang menyerang lebih dari 85% kalangan remaja di seluruh dunia. Penyebab terjadinya jerawat yaitu bakteri Propionibacterium acnes (P. acnes).  Tujuan dari penelitian eksperimental ini yakni untuk membuat formulasi dan menganalisis aktivitas gel ekstrak daun jeruk manis terhadap bakteri P. acnes. Ekstrak daun jeruk manis diekstraksi kemudian dilakukan formulasi gel menggunakan gelling agent karbopol dengan berbagai konsentrasi 0,5%, 1%, 1,5%, dan 2%. Selanjutnya, dilakukan uji kestabilan dan aktivitas terhadap bakteri Propionibacterium acnes menggunakan metode difusi cakram. Hasil uji stabilitas sediaan menunjukkan bahwa formulasi gel dengan karbopol 2% dan konsentrasi ekstrak 20% merupakan yang paling stabil dibanding formulasi lainnya serta memiliki aktivitas daya hambat terhadap bakteri P. acnes kategori lemah dengan zona hambat 1,8 mm. Berdasarkan hasil dari penelitian ini, sediaan gel ekstrak daun jeruk manis memiliki aktivitas daya hambat terhadap bakteri P. acnes penyebab jerawat. Lebih jauh, tanaman ini dapat digunakan sebagai alternatif pengobatan untuk mengatasi jerawat.
DOCKING SENYAWA AGLIKON KURKULIGOSIDA A DAN TURUNANNYA TERHADAP ENZIM ALDOSA REDUKTASE
Authors: Nursamsiar Nursamsiar , Jum Achnis Akbar , Aksa Rahmad , Marwati Marwati , Nur Syamsu
Published: June 2022

Senyawa aglikon kurkuligosida A memiliki kemiripan struktur dengan butein yang memiliki aktivitas penghambatan terhadap aldosa reduktase, sebagai salah satu target terapi komplikasi diabetes. Penelitian ini bertujuan untuk mengetahui interaksi antara senyawa aglikon kurkuligosida A dan turunannya terhadap enzim aldosa reduktase dengan metode docking molekuler. Docking dilakukan dengan menggunakan program AutoDock 4.2, dengan menambatkan senyawa aglikon kurkuligosida A dan turunannya pada sisi aktif aldosa reduktase secara in silico. Hasil docking menunjukkan senyawa turunan aglikon kurkuligosida A dapat berinteraksi dengan sisi aktif. Interaksi terbaik ditunjukkan oleh senyawa 36 (3,5-dihidroksibensil-3-bromobensoat), senyawa 39 (3,5-dihidroksibensil-4-nitrobensoat), senyawa 52 (4-hidroksibensil-4-nitrobensoat) dengan nilai energi bebas ikatan berturut-turut -10.09 kkal/mol, -10.07 kkal/mol, dan -10.33 kkal/mol yang berinteraksi dengan residu asam amino penting pada aldosa reduktase dan memiliki ikatan hidrogen yang sama pada Tyr48, His110 dan Trp111 dengan menggunakan ligan alami [2-(4-bromo-2-fluoro-benzylthiocarbamoyl)-5-fluoro-phenoxy]-acetic acid sebagai pembanding.
AKTIVITAS ANTIBAKTERI DESINFEKTAN BERBAHAN DASAR ASAP CAIR CANGKANG KELAPA SAWIT TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS
Authors: Rosmainar Lilis , Karelius Karelius , Toemon Angeline Novia
Published: June 2022

Cangkang kelapa sawit merupakan limbah pengolahan kelapa sawit yang dapat digunakan untuk menghasilkan asap cair. Asap cair dapat digunakan sebagai pengawet, antibakteri  terutama mengandung asam asetat dan fenol. Tujuan dari penelitian ini adalah menguji efektivitas antibakteri desinfektan berbahan dasar asap cair pada berbagai konsentrasiterhadap pertumbuhan bakteri Staphylococcus aureus. Pembuatan asap cair dilakukan melalui proses torefaksi dengan pemberian gas nitrogen sehingga menghasilkan asap cair dari cangkang kelapa sawit yang berwarna kehitaman yang mengandung senyawa fenol, asam propanoat, 2-propanon, 1,2-benzendiol, 2-furankarbokaldehid, dan asam asetat. Asap cair hasil torefaksi kemudian didestilasi sehingga menghasilkan warna coklat yang kemudian dianalisis menggunakan GC-MS dengan kandungan senyawa fenol, asam propanoat, 2 propana, dan asam asetat. Desinfektan berbahan dasar asap cair dibuat dengan berbagai konsentrasi yaitu 12,5%, 25%, dan 50% diuji terhadap bakteri S.aureus. Pada uji antibakteri desinfektan berbahan asap cair dengan berbagai konsentrasi tidak ditemukan adanya pertumbuhan bakteri S.aureus.Hal ini menunjukkan bahwa desinfektan berbahan dasar asap cair efektif dalam menghambat bakteri S.aureus.
Senyawa Sitotoksik dari Fraksi Diklorometana Kulit Terong Ungu (Solanum melongena L.) Terhadap Sel Kanker Payudara T47D
Authors: Widiyantoro Ari , Harlia Harlia , Prasetya Banu
Published: June 2022

Eggplant (Solanum melongena L.) is a plant that contains antioxidants and potentially as a cancer drug. This study was conducted to identify the cytotoxic activity of secondary metabolite compound against T47D breast cancer cells based on the IC50 value. Isolation Eggplant peel was carried out in several steps, such as maceration, partition, and chromatography.The result 1H-NMR (DMSO, 500 MHz) analysis optained a chemical shift of δ 0.86 ppm (1H,m), δ 1.44 ppm (1H,s), δ 1.34 ppm (2H, brs), δ 1.62 ppm (1H, m), δ 3.31 ppm (4H, brs), δ 3.73 ppm (1H, t), dan δ 7.69 ppm (1H,m). Based on the chemical shift 3 ' isolate tends to have similarities to the aglycon pregnan compound steroids. The results showed that the dichloromethane fraction obtained IC50 values of 160.79 µg / mL and the isolate obtained IC50 values of 124.44 µg / mL. The IC50 value obtained by the dichloromethane fraction and isolate was classified as moderate cytotoxic so that it could be used to prevent and inhibit the growth of cancer cells.
EKSTRAKSI FLAVONOID DAUN MENIRAN MENGGUNAKAN PELARUT NATURAL DEEP EUTECTIC SOLVENT BERBASIS KOLIN KLORIDA-ASAM DENGAN ULTRASOUND ASSISTED EXTRACTION
Authors: . Yulianita , Rusli Zaldy , Suhendar Usep , Masrani Zulfa
Published: June 2022

Penggunaan pelarut organik masih umum digunakan untuk menarik senyawa aktif, diantaranya adalah flavonoid yang berperan dalam kesehatan manusia sebagai antioksidan, antikanker, dan antidepresan. Akan tetapi, penggunaan pelarut organik sebenarnya berbahaya bagi kesehatan, karena dapat mempengaruhi sistem saraf pusat dan perifer, sistem reproduksi, menginduksi kanker, dan lain-lain.  Penelitian ini bertujuan untuk menentukan pelarut terbaik dari beberapa kombinasi Natural Deep Eutectic Solvent (NADES) dan metode ekstraksi daun meniran terhadap kadar flavonoid.Pengujian kadar flavonoid dilakukan dengan metode penambahan AlCl3. Hasil penelitian diperoleh kadar flavonoid terbaik pada pelarut NADES 2 yaitu kombinasi Kolin Klorida-Asam Oksalat dengan kondisi ekstraksi optimum pada suhu 48oC, waktu 60 menit dan rasio pelarut NADES:Air 90% sebesai 1,4161% . Berdasarkan penelitian ini, diketahui bahwa ekstraksi menggunakan pelarut NADES tersebut lebih baik dibandingkan metode konvensional dan kombinasi pelarut NADES lainnya.
ECOTOURISM DEVELOPMENT STRATEGY OF TANGGAMUS REGENCY, LAMPUNG PROVINCE (CASE STUDY: TELUK KILUAN)
Authors: Nurbaihaqi Fariz Fardani , Maryani Enok , Andari Rini
Published: June 2022

This research was conducted to identify the potential of ecotourism in Tanggamus district in optimizing the role of tourism in the economy and community welfare, it is necessary to develop a sustainable tourism development based on an adequate understanding of the characteristics, conditions and constraints faced by tourism business actors. This development needs to be supported by appropriate financing and investment schemes. This research is qualitative research with a descriptive method with an inductive approach or solving existing problems and finding a complete understanding of the object being observed with research, as well as collecting data through direct observations made by researchers on 25-28 February 2022, interviews and documentation. In collecting qualitative data, the author conducted interviews with 20 informants using the snowball method consisting of the Head of the Tourism and Culture in Tanggamus Regency, Communities around tourist objects, tourists, managers, and MSME business actors. The development of tourist areas has not involved stakeholders outside the village, such as universities and the private sector. The absence of regulations on the management of ecotourism areas, the lack of budget allocations, the absence of a uniform cost system related to entrance tickets and profit sharing between the village and the manager, the opportunistic behavior of a small part of the community are institutional obstacles in the development of the ecotourism area. Based on the results of the study in this study, the proposed development of coastal ecotourism areas is sustainable tourism, which involves local governments, the private sector, academics, local communities, and the mass media.
THE ROLE OF INSTAGRAM MEDIA IN BRANDING DESTINATIONS AMONG YOUTH IN BUKITTINGGI CITY
Authors: Asyraf Jovan Abdul , Maryani Enok , Andari Rini
Published: June 2022

The purpose of this study was to identify the role of Instagram media in Destination Branding among teenagers in Bukittinggi City. The method used in this study is a qualitative descriptive method, to present a complete picture of the role of Instagram media with the Instagramable phenomenon in the formation of branding destinations among final year teenagers. The results of this study are to identify the extent to which Instagram media plays a role in the formation of branding destinations among late-level teenagers. This research was conducted by discussing Tourism, Branding Destinations, New Media (Instagram), Instagramable, and Gen Z specifications for late teens with an age range of 18-21 years and taking a case study in Bukittinggi City.