bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Competence Terhadap Organization Performance Yang Dimediasi Oleh Strategic Change Management Pada Umkm Di Sidoarjo Saat Pandemi Covid-19
Authors: Ashari M. Irfan Robby , Sukarno Gendut , Rini Hesty Prima
Published: June 2023

ABSTRACTThe purpose of this study was to determine whether the variables of strategic change management can be a mediation of the variables of organization performance with variable competence of the organization of Micro, Small and Medium enterprises in Sidoarjo Regency. The primary Data used in this Study was obtained through questionnaires to the target respondents represent the population and secondary data obtained through the official website of the Department of Cooperatives and Micro, Sidoarjo Regency. This study observed the performance of the organization of Micro, Small and Medium enterprises in the District of Sidoarjo. This research uses quantitative analysis to determine the value of the responses of respondents to the variables used in the study, by using the software SmartPLS. The results of this study successfully proved that the strategic change management has the role of mediation between the Competence to Organization performance with the value of the path coefficients of 0,245, and the value of T-statistic of 2,980 > 1,96 (from table value Za = 0,05) or P-values of 0.003 (smaller than 0.05) on the organization of Micro, Small and Medium enterprises in the District of Sidoarjo. ABSTRAKPenelitian ini bertujuan untuk mengetahui apakah variabel strategic change management dapat memediasi variabel organization performance dengan variabel competence pada organisasi UMKM yang ada di Kabupaten Sidoarjo. Data primer yang dipakai dalam penelitian ini adalah data yang didapat dari penyebaran kuesioner kepada target responden yang mewakilkan populasi dan data sekunder yang dipakai dalam penelitian ini adalah data yang didapat dari website resmi Dinas Koperasi dan Usaha Mikro Kabupaten Sidoarjo. Penelitian ini menggunakan analisis kuantitatif untuk menentukan nilai respon dari responden pada variabel yang digunakan dalam penelitian, dengan menggunakan piranti lunak SmartPLS. Hasil dari penelitian ini berhasil membuktikan bahwa strategic change management dapat memediasi antara variabel competence dengan variabel organization performance dengan nilai path coefficients sebesar 0,245, dan nilai T-statistic sebesar 2,980 > 1,96 (dari nilai tabel Zα = 0,05) atau P-values sebesar 0,003  (lebih kecil dari 0,05)
PENGARUH PROFESIONALISME, INTENSITAS MORAL, DAN PERSONAL COST OF REPORTING TERHADAP INTENSI AUDITOR MELAKUKAN WHISTLEBLOWING
Authors: Anggraeni Eirene Dewi , Haryati Tantina
Published: June 2023

Dalam dunia kerja seorang auditor, terdapat dua aspek terpenting dalam pekerjaannya, yaitu profesionalisme dan intensitas moral. Bukan hanya untuk mengungkapkan kewajaran atas laporan keuangan sebuah perusahaan, namun juga dalam mengungkap tindak kecurangan dalam laporan keuangan. Selain profesionalisme dan intensitas moral, terdapat personal cost of reporting yang menjadi pemikiran paling pertama sebelum seseorang melakukan whistleblowing karena jika tindakan pelaporan yang dilakukan akan membahayakan dan memberi dampak buruk terhadap dirinya, maka akan membuat kecenderungan seseorang untuk melakukan pelaporan menjadi sangat minim. Penelitian ini dilakukan guna mengetahui pengaruh atas profesionalisme, intensitas moral, dan personal cost of reporting terhadap intensi auditor melakukan whistleblowing. Penelitian ini penelitian kuantitatif dari data kuesioner google form. Populasi sebanyak 130 auditor yang bekerja pada KAP di Surabaya., sedangkan sampel penelitian sebanyak 98. Analisis data dibantu dengan software SmartPLS. Berdasarkan hasil penelitian, diperoleh hasil profesionalisme dan intensitas moral berpengaruh signifikan terhadap intensi auditor melakukan whistleblowing, sedangkan personal cost of reporting tidak berpengaruh signifikan terhadap intensi auditor melakukan whistleblowing.
ANALISIS PENGARUH KARAKTERISTIK DEWAN TERHADAP KESULITAN KEUANGAN PADA PERUSAHAAN DI INDONESIA
Authors: Listari Dian Ayu , Karina Ria
Published: June 2023

This research generally aims to gain new knowledge and discoveries about the importance of the impact of good corporate governance on the board on financial difficulties to prevent bankruptcy of the company. The research was conducted using a purposive sampling method, with the object of research being companies that have been listed on the Indonesia Stock Exchange. The company must have a complete annual report from 2016 to 2020 and use the rupiah currency. The dependent variable in this study is financial difficulties followed by three independent variables, namely the size of the board of directors, the independence of the board and the activity of the board. There are also control variables in the study in the form of return on equity and solvency ratios. The results of this study indicate that there is a significant positive effect between the size of the board of directors and the company's financial difficulties, the independence of the board does not have a significant effect on financial difficulties and board activities have a significant positive effect on the dependent variable, namely financial difficulties. As the return on equity control variable has a significantly positive effect on financial difficulties, the solvency ratio does not have a significant effect on financial difficulties
Apakah Efektivitas Komite Audit dan Kualitas Audit mempengaruhi Manajemen Laba
Authors: Manurung Roberto , Siagian Valentine
Published: June 2023

This study was conducted to determine whether the effectiveness of the audit committee and audit quality affect the earnings management of the pharmaceutical sub-sector listed on the IDX. In this research, the data used are the financial statements of 8 pharmaceutical companies listed on the Indonesia Stock Exchange (IDX) for the period 2016 – 2019. The results of this study indicate that audit committee members do not affect earnings management. Total meetings have an influence on earnings management. Audit quality has an influence on earnings management. The results of all these studies have an influence between the effectiveness of the audit committee with the proportion of the number of committee members and the number of meetings and audit quality on earnings management.
ANALISIS KINERJA KEUANGAN TERHADAP PERTUMBUHAN LABA SELAMA PANDEMI COVID-19 PADA PERUSAHAAN SEKTOR INFRASTRUKTUR YANG TERDAFTAR DI BEI
Authors: Asha Indri Adinda , Fatimah Ari Nurul
Published: June 2023

Munculnya pandemi Covid-19 menyebabkan adanya permasalahan di berbagai sektor, salah satunya pada sektor perusahaan infrastruktur. Tujuan dilakukannya penelitian ini adalah untuk menguji dan menganalisis pengaruh kinerja keuangan perusahaan yang terdiri atas rasio WCTA, OITL, NPM, DER, dan DAR terhadap pertumbuhan laba pada perusahaan sektor infrastruktur yang terdaftar di Bursa Efek Indonesia (BEI) selama pandemi Covid-19. Dalam penelitian ini menggunakan metode kuantitatif dengan data sekunder yang diperoleh dari laman www.idx.co.id. Terdapat sebanyak 19 perusahaan yang menjadi sampel penelitian ini, dengan data periode laporan keuangan tahunan yaitu tahun 2020 dan 2021 dengan kriteria tertentu. Pengujian data yang dilakukan dalam penelitian ini dengan menggunakan uji asumsi klasik yang terdiri atas uji normalitas, uji multikolinearitas, uji heteroskedastisitas, dan uji autokorelasi. Kemudian, pengujian hipotesis dilakukan dengan metode regresi linear berganda dengan menggunakan uji koefisien determinasi, uji simultan, dan uji parsial. Berdasarkan pengujian yang telah dilakukan, hasil dari penelitian ini dapat diketahui bahwa kinerja keuangan WCTA, DAR, DER memiliki pengaruh positif terhadap pertumbuhan laba, sedangkan kinerja keuangan NPM dan OITL tidak memberikan pengaruh terhadap pertumbuhan laba perusahaan.
PENGGUNAAN TEKNIK AKUNTANSI FORENSIK DALAM PENDETEKSIAN DAN PENCEGAHAN OCCUPATIONAL FRAUD: KAJIAN LITERATUR
Authors: Christian Natalis , Resnika Resnika
Published: June 2023

Kecurangan yang berhubungan dengan pekerjaan (occupational fraud and abuse) merupakan ancaman terbesar bagi keberlangsungan usaha suatu korporasi. Penyalahgunaan aset, manipulasi laporan keuangan, dan korupsi merupakan kategori kecurangan yang melibatkan jabatan seseorang untuk mencapai keuntungan pribadi. Tujuan penelitian adalah mengetahui metode pendeteksian dan pencegahan kecurangan dari perspektif akuntansi forensik. Metode penelitian secara kualitatif dilakukan dengan mengumpulkan dan mengkaji sumber riset dan dokumentasi yang relevan dengan penelitian. Hasil pengumpulan data menunjukkan bahwa metode pendeteksian kecurangan cenderung bersifat pasif. Pendekatan deteksi kecurangan yang bersifat pasif biasanya menggunakan metode non analitis seperti laporan rahasia, kebetulan, penegakan hukum, dan sebagainya. Sementara itu, teknik akuntansi forensik dapat diterapkan apabila perusahaan ingin mengambil langkah yang proaktif dalam memberantas kecurangan. Teknik akuntansi forensik melibatkan prosedur analitis dan perangkat lunak statistik untuk pengolahan data yang berjumlah besar. Metode analitis tersebut memiliki keunggulan dalam pendeteksian kecurangan yang akurat dengan durasi waktu yang singkat. Namun, keterbatasan dari metode tersebut adalah biaya yang mahal serta preferensi perusahaan terhadap metode non analitis yang bersifat pasif. Kajian literatur dalam penelitian ini dapat memberikan pemahaman komprehensif mengenai pro dan kontra serta gambaran teknik pendeteksian kecurangan perusahaan.
ANALISA KUALITAS LAYANAN PADA CV. SINGOYUDHO NUSANTARA
Authors: Apriliana Apriliana , Sukaris Sukaris
Published: June 2023

The purpose of this research is to identify service quality factors and identify ways that can be done to improve service quality. This research was conducted at CV.Singoyudho Nusantara which is located in Betoyokauman Village, Betoyokauman Village, Manyar Gresik District, East Java. This type of research is descriptive qualitative research. The data source used is the primary data source. Retrieval of data in this study using observation, interviews, and documents. The results that can be concluded in this study identify the quality of service that must be implemented by suppliers, namely being listed as a vendor who has AK3 and CSMS certificates, implementing 6 on namely on safety, on time, on scope, on quality, on cost and on clean, has work experience , the qualifications of the quality of the goods as evidenced by material tests and the speed of delivery and the payment system in the form of non-cash invoices. CV.Singoyudho Nusantara has implemented service quality, in the form of Reliability: levering accuracy, delivery speed is able to accommodate urgent goods. Assurance : polite appearance and in accordance with speech . Responsiveness: always responds quickly when problems occur. Assurance: always maintain politeness in both behavior and speech. Empathy: responsive and fast in communication. To increase customer satisfaction, the methods or strategies that can be implemented are to avoid miscommunication between CV.Singoyudho and customers, always respond quickly when contacted by customers and improve service quality according to standards in customer companies.
Pengaruh Penataan Arsip Terhadap Efektifitas Kerja Pegawai Pada Kantor PT. PLN (Persero) UP3 Ambon
Authors: Hahury Jessy Juniu
Published: June 2023

This study aims to find out how the influence of archive management on the work effectiveness of employees of PT. PLN (Persero) UP3 Ambon. The problems faced by PT. PLN (Persero) UP3 Ambon, namely: Not optimal arrangement of archives at the office, where archives are only placed in several containers such as: on cardboard, plastic, or just stacked. As a result, it causes disruption to the archive retrieval process because it is not stored in one good place, thus disrupting the service process for its users and requiring a long time (more than 30 minutes) to search for the required data, whereas in theory The Liang Gie (2007) ) archive discovery standard 1 minute. Simple linear regression analysis according to Riduwan (2010) regression or forecasting is a process of systematically estimating what is most likely to happen in the future. based on past and present information that is owned so that errors can be minimized.
used to test the effect of the independent variable (independent) namely the arrangement of files (X) on the dependent variable (the dependent) namely work effectiveness (Y). Arranging archives or managing archives needs to be done properly and maximally, in order to make it easier for employees to carry out their duties so as to increase employee effectiveness. Archival facilities owned by PT. PLN (Persero) UP3 Ambon is not sufficient, only (two) 2 wooden cupboards and several odner folders are available for storing archives. There is no special room for archive storage, so archives are stored in the meeting room or in the employee's office. The lack of facilities as a tool to support the equipment used is also a major factor in the smooth running of the filing process. So far, archive handling has been handled by employees who also hold the position of secretary, causing archive management to be ineffective, because the work being done is not focused on one area. just.
Based on the results of partial hypothesis testing, it shows that the Archive Management variable (X) has a positive and significant effect on employee work effectiveness (Y) at PT. PLN (Persero) UP3 Ambon. This is evidenced by the coefficient value of the archive management variable of 4.422 which is greater than t table of 2.048407 and the significant value of the employee work effectiveness variable of 0.00 which is less than 0.05, this means that Ha is accepted. In conclusion, the arrangement of archives affects the work effectiveness of employees at the PT. PLN (Persero) UP3 Ambon..
IMPLEMENTASI REMOTE AUDIT DI ERA PANDEMI COVID-19
Authors: AWISIANTI MITA , Susilo Ghina Fitri Ariesta
Published: June 2023

The COVID-19 pandemic has caused the structure of life to change, such as the way auditors work. All access is limited and the auditor's work is hampered. So one alternative that can be done is to carry out a remote audit. This study aims to determine the implementation of remote audits in the era of the COVID-19 pandemic. This study uses a qualitative approach and is included in the literature review. The data used by researchers is secondary data, namely using previous research. Sources of information are obtained by collecting relevant information regarding the implementation of remote audits in the era of the COVID-19 pandemic. The results of the study show that the implementation of remote audits has been carried out by foreign government entities and by domestic agencies or institutions. The remote audit implementation includes the planning stages, document review, field inspections, remote interviews and closing meetings.
ANALISIS KINERJA KEUANGAN BANK RAKYAT INDONESIA SEBELUM DAN SELAMA MASA PANDEMI COVID – 19 : STUDI KOMPARATIF
Authors: Budianto Achyat , Rozi A. , Tanjung Ferri Saputra , Marnas Marnas , Andriani Beid Fitrianova
Published: June 2023

This study aims to examine the differences in the financial performance of PT Bank Rakyat Indonesia before and during the COVID-19 pandemic. This test uses a quantitative approach, and the data samples used from the third quarter of 2017 to the second quarter of 2022 are 20 samples. Bank Rakyat Indonesia, as the research object, has the most customers among other banks. Testing was carried out using the paired sample t-test method. The results of the study show differences in financial performance before and during the COVID-19 pandemic in the ratios of NPL, ROA, ROE, and LDR, but there is no difference in financial performance before or during the COVID-19 pandemic in the BOPO ratio
AKUNTANSI SEKTOR PUBLIK UNTUK MENCEGAH FRAUD PADA SEKTOR PUBLIK DI ERA DIGITAL
Authors: Putri Angel Novita , Retnosari Retnosari
Published: June 2023

Government agencies are guided by the public sector accounting recording method which contains the accounts used in recording the operations of government agencies. High-level state entities and agencies, which include municipalities, agencies, major parties, and many other non-profit organizations, are covered by public sector accounting. Public sector accounting is closely related to the digital era because it will be used for the publication of financial reports. The purpose of this study is to see the impact of public sector accounting as a means of fraud prevention in the public sector in the digital era. This study used a qualitative approach using descriptive techniques to explain the results of the study. The results of the research produced are that public sector accounting has a close relationship with fraud prevention. in other words, through a positive attitude that is applied to the existence of digitalization, it will determine a device as a problem or responsibility that can be used as a form of increasing identity
PERAN OTORITAS JASA KEUANGAN (OJK) DALAM PENGAWASAN DAN PENCEGAHAN INVESTASI ILEGAL DI INDONESIA
Authors: Rohmatun Rohmatun , Argarinjani Restu , Panggiarti Endang Kartini
Published: June 2023

OJK is an institution that is tasked and responsible for supervising and preventing illegal investments, as stipulated in Law No. 21 of 2011 concerning OJK. OJK plays a role in overseeing all activities engaged in the financial services sector, one of which is illegal investment, so it is important for OJK to provide direction and legal protection to the wider community, especially those who have or will invest in the financial services sector, as well as people who invest in Indonesia. This research is important for OJK to provide knowledge about these investments. This research was conducted using the library law method. Based on the results of the research, it is found that according to Law Number 21 of 2011, OJK is an institution that has enormous authority, but at the same time it is also an institution that has the task of regulating and supervising all financial services institutions in Indonesia and the role of the prevention and supervision of the Financial Services Authority on illegal investments has had a positive influence on investment activities in Indonesia, starting with regulation and supervision as well as several other prevention and prosecution roles.
ANALISIS EFEKTIVITAS RETRIBUSI DAERAH SEBAGAI SUMBER PEMBIAYAAN OTONOMI DAERAH (PAD) DI KOTA MAGELANG TAHUN 2017-2021
Authors: Zahro Nilna Syifa , Lestari Dian , Manurung Herlina
Published: June 2023

This research aimed to describe the magnitude of the effectiveness of the remuneration of the region as a source of financing of autonomous areas in the city of Magelang. Analyze the effectiveness of the acceptance of regional remuneration as a source of financing of autonomous areas applied in the city of Magelang. The use of data in this research is secondary data. The study uses quantitative descriptives as a method of data analysis with the calculation of efficiency ratio to analyze target data and realization of remuneration receipt of the region over the last five years, which is taken from the data of the implementation report of the budget PAD Kota Magelang Year 2017-2021. The results of this study show that those that do not reach the level of efficiency are in 2020 only reach 69,7615%, while for the years 2017-2019 and 2021 already effective, that is, in 2017 by 115,128%, in 2018 by 114,931%, in 2019 by 131,217%, and in 2021 by 124,286%. Therefore, the extent to which the rehab of the area as a source of autonomous financing of the region has increased has been sufficiently effective and efficient.
PENGARUH RASIO PROFITABILITAS TERHADAP HARGA SAHAM PADA PERUSAHAAN SUB SEKTOR INDUSTRI TEKSTIL DAN GARMEN TERDAFTAR GO PUBLIK DI BURSA EFEK INDONESIA PERIODE 2018-2022
Authors: Evrina Evrina , Rozi A. , Mariana Repilia , Budianto Achyat
Published: June 2023

This research was conducted to examine the effect of return on assets (ROA) and net profit margin (NPM) on share prices in textile and garment industry sub-sector companies that go public on the Indonesia Stock Exchange for the 2018–2022 period. The approach used in this research is an associative one. In this study, there were 10 companies as a population, with 2 companies used as a sample. The source of the data used in this study is the financial statements of the textile and garment industry sub-sector companies that went public on the Indonesia Stock Exchange for the 2018–2022 period. The data collection technique used in this study is the documentation technique. In this study, there were five types of data collection techniques: descriptive statistics, classical assumptions test, multiple linear regression analysis, hypothesis testing, and coefficient of determination. The results of this study prove that return on assets (ROA) and net profit margin (NPM) partially affect stock prices. And simultaneously, return on assets (ROA) and net profit margin (NPM) affect share prices in textile and garment industry sub-sector companies that go public on the Indonesia Stock Exchange for the 2018–2022 period.
‘To See a World in a Grain of Sand’: Glass from Nubia and the Ancient Mediterranean
Authors: Juliet V. Spedding
Published: June 2023

‘To See a World in a Grain of Sand’ uses modern scientific methods to examine glass beads and vessel fragments dating from the Meroitic (c. 350 BC-AD 350) and Early Nobadia (c. AD 350-600) periods to provide a new assessment of glass from Nubia (ancient Sudan), a subject hitherto little-studied. The resulting identification of their chemical makeup is not simply about artefact reclassification but permits the tracking of similar compositions and—by extension—the raw materials for glass production that were used throughout Nubia, Egypt, and the Mediterranean. The results reveal interrelationships between trade, technological understanding, and manufacturing choices made across these cultures. Comparing glasses from Nubia with those from Egyptian and Mediterranean contexts has also shown how the same primary production centres were providing glass to sites in Turkey, Albania, Egypt, and Nubia. The identification of different glass groups and rare types of glass within Nubia shows the extent and variation to be found in a material that is present not only at a single site but also across the whole region, while the data presented reveals the diverse and complex nature of glass objects discovered there. That multiple interactions were being employed in glass manufacture shows how the examination of artefacts and their component materials must include consideration of both international trade and ‘home-based’ practices.
Personal Religion in Domestic Contexts during the New Kingdom
Authors: Iria Souto Castro
Published: June 2023

Personal religion in Domestic Contexts during the New Kingdom compiles artefacts and fixed emplacements in domestic settings during the New Kingdom in ancient Egypt that, from a comparative approach, are interpreted as examples of religious practices, contributing to the study of the so-called ‘Archaeology of Religion’. By including the two main and best preserved sites for this research, namely Tell el-Amarna and Deir el-Medina, parallel cases for other sites with similar features are provided. At the same time, particular topics are explored throughout the book, including early evidence of personal religion as well as questions referring to the socioeconomic roles of the inhabitants of such main sites. Overall, there are three main themes: the definition of personal religion and religious domestic practices from a theoretical perspective; the description and analysis of the main archaeological and anthropological evidence; and, on that basis, the study of the impact of the Amarna period in the development of personal religion during the New Kingdom.
Is neutrophil lymphocyte ratio magic or not?
Authors: SAHİN Fatih , ODACILAR Ali Şahap , GÜNKAYA Osman Samet , ADAN Ramazan , SARAÇ Enes , GENÇ Simten , YURCİ Arzu , AKBAYİR Ozgur
Published: June 2023

Aim: To evaluate the predictive value of preoperative ratio of neutrophils to lymphocytes (NLR) in distinguishing between benign and malignant masses, as inflammation plays a significant role in the development and emergence of cancer.

Material and Method: This retrospective study included 155 patients who underwent surgery due to an adnexal mass between December 2020 and December 2021 (55 were malignant, 100 were benign). Age, parity, tumor stage, chemotherapy, CA 125, CRP, neutrophils, lymphocytes, NLR, were recorded. The Mann-Whitney, the Chi-square test and multiple linear regression were used. The cut-off values of the variables were determined by calculating the areas under the receiver operating characteristic curve (ROC) for the purposes of differential diagnosis in the presence of malignancy, and by analyzing the sensitivity, specificity, positive predictive value, negative predictive value, and likelihood-ratio (LR) (+) values. A P-value of 2.79 for NLR; sensitivity was found to be 59.36%, specificity 75.51%, positive predictive value (PPV) 58.44, negative predictive value 75.58, LR (+) value 2.3. At cut-off> 36.9 for CA-125; sensitivity was 80.00%, specificity was 78.63%, positive predictive value was 67.72%, negative predictive value was 87.53%, LR (+) value was 3.73.

Conclusion: The primary outcome of our study is that the likelihood of malignancy in a patient with an NLR value of>2.79 is 2.3 times higher than in a patient with an NLR value of 36.9 is 3.73 times higher than in a patient with a CA-125 value of
The relationship between Hashimoto's thyroiditis and vitamin D and the inflammatory marker platelet-to-lymphocyte ratio
Authors: KOÇ Gönül , ARSLAN-SÜZER Ayşe , GÜRSOY Gül
Published: June 2023

Aim: Hashimoto's thyroiditis (HT) is a chronic autoimmune-mediated disease that leads to overt hypothyroidism. Vitamin D is essential for immunity. This study examines possible impacts of vitamin D on the progression of HT and evaluates the use of platelet-lymphocyte ratio (PLR) as an indicator of its relationship with the inflammatory process.

Material and Method: This is a retrospective case-control study, consisting of 60 individuals with HT and 40 healthy controls. Thyroid function tests, thyroid antibodies, vitamin D levels, erythrocyte sedimentation rate (ESR), parameters of complete blood count and C-reactive protein (CRP) levels were scanned retrospectively using participants' medical files between September 2018 and March 2019. Platelet count was divided by lymphocyte count to determine PLR.

Results: HT patients had both considerably lower median vitamin D levels and higher percentages of vitamin D deficiency than the controls [12.08 (8.79–17.00) vs. 20.09 (20.00–34.00) and 80% vs. 22.5%, respectively, p
Comprehensive serum lipidomic analyses reveal potential biomarkers for malignant breast cancer: A case-control study1
Authors: Cao Bing , Yang Siyu , Yan Lailai , Li Nan
Published: June 2023

BACKGROUND: Breast cancer is the most worldwide commonly found malignancy among women. The evidence for lipidomic studies of breast cancer in the Chinese population is relatively limited. OBJECTIVE: Our current study aimed to identify peripheral lipids capable of distinguishing adults with and without malignant breast cancer in a Chinese population and to explore the potential lipid metabolism pathways implicated in breast cancer. METHODS: Lipidomics was performed with an Ultimate 3000 UHPLC system coupled with a Q-Exactive HF MS platform by using the serum of 71 female patients with malignant breast cancer and 92 age-matched (± 2 years) healthy women. The data were uploaded to and processed by the specialized online software Metaboanalyst 5.0. Both univariate and multivariate analyses were carried out for potential biomarker screening. Areas under the receiver-operating characteristic (ROC) curves (AUCs) of identified differential lipids were obtained for evaluating their classification capacity. RESULTS: A total of 47 significantly different lipids were identified by applying the following criteria: false discovery rate-adjusted P < 0.05, variable importance in projection ⩾ 1.0, and fold change ⩾ 2.0 or ⩽ 0.5. Among them, 13 lipids were identified as diagnostic biomarkers with the area under curve (AUC) greater than 0.7. Multivariate ROC curves indicated that AUCs greater than 0.8 could be achieved with 2–47 lipids. CONCLUSIONS: Using an untargeted LC-MS-based metabolic profiling approach, our study provides preliminary evidence that extensive dysregulations of OxPCs, PCs, SMs and TAGs were involved in the pathological processes of breast cancer. We provided clues for furtherly investigating the role of lipid alterations in the pathoetiology of breast cancer.
Effects of surface wettability of silicon-incorporated diamond-like carbon films on barnacle larval settlement
Authors: Ozeki K. , Nakahara S.
Published: June 2023

The colonization of barnacles on surfaces has detrimental effects on shipping, leisure vessels, heat exchangers, oceanographic sensors, and aquaculture systems. One strategy for avoiding barnacle colonization on surfaces is to utilize surface wettability. Silicone-incorporated diamond-like carbon (Si-DLC) has high hardness and a low friction coefficient, and an increase in the incorporation of Si leads to hydrophobicity. By contrast, oxygen plasma treatment produces hydrophilicity in Si-DLC films. The improved surface wettability of Si-DLC may reduce barnacle colonization. However, few studies have been conducted on barnacle larval settlement in relation to Si-DLC films. The aim of this study is to evaluate barnacle larval settlement on Si-DLC films and on oxygen-plasma-treated Si-DLC films. Si-DLC films were prepared by radio-frequency plasma-enhanced chemical vapor deposition and treated with oxygen plasma. The films were characterized using Raman spectroscopy and X-ray photoelectron spectroscopy. Contact angles of the films were measured to evaluate their hydrophobicity. Barnacle cyprid larva settlement was observed on the Si-DLC and oxygen-plasma-treated Si-DLC films. The contact angle of the Si-DLC-0% film was 69.9 ± 3 . 3 ∘ and increased with Si incorporation. Following oxygen plasma treatment, the contact angle of the Si-DLC-0% films decreased to 10.9 ± 4 . 4 ∘ and gradually increased with Si incorporation. The barnacle cyprid larval settlement ratio for the non-coated stainless plate was 36.4%, whereas that of the DLC films was 15.0%, which decreased with Si incorporation. Following oxygen plasma treatment, the ratio of barnacle cyprid larval settlement in Si-DLC films was lower than for the Si-DLC films. The Si-DLC film was effective in avoiding barnacle adhesion, whereas the oxygen-plasma-treated Si-DLC was even more effective. This study demonstrated the feasibility of Si-DLC for antifouling against barnacles.
Research of Russian physicians’ opinions on tuberculosis pharmacogenetics
Authors: Kantemirova B.I. , Bogorodskaya E.M. , Poptsova M.S. , Sychev D.A. , Tsimbal E.A. , Stepanova N.A.
Published: June 2023

BACKGROUND: There is currently no widespread implementation of pharmacogenetic testing (PGx) methods in the practice of phthisiology service. OBJECTIVE: The aim of this study is to determine how informed and prepared phthisiologists, residents, and postgraduate students of the Russian Medical Academy of Continuing Professional Education (RMACPE, Moscow) use PGx techniques in their work to improve treatment safety, predict the occurrence of adverse reactions (ADRs), and personalize therapy. METHODS: A survey was conducted among phthisiologists (n = 314) living in different regions of the Russian Federation and studying at RMACPE, such as residents and post-graduate students (n = 185). The survey was developed on the Testograf.ru web platform and had 25 questions for physicians and 22 for residents and post-graduate students. RESULTS: More than 50% of respondents are ready to use PGx in clinical practice and thus are aware of the method’s possibilities. At the same time only a small part of participants were aware of the pharmgkb.org resource. The absence of PGx in clinical guidelines and treatment standards, according to 50.95% of phthisiologists and 55.13% of students of RMACPE, the absence of large-scale randomized clinical trials, according to 37.26% of phthisiologists and 43.33% of students, and the lack of physician knowledge on PGx, according to 41.08% of phthisiologists and 57.83% of students, are all factors that prevent the implementation of PGx in Russia. CONCLUSION: According to the survey, the overwhelming majority of participants recognize the importance of PGx and are willing to use the method in practice. However, there is a low level of awareness among all respondents about the possibilities of PGx and the pharmgkb.org resource. The implementation of this service could significantly increase patient compliance, lower ADRs, and enhance anti-tuberculosis (TB) therapy quality.
Evaluation of errors in preparation and administration of intravenous medications in critically ill patients
Authors: Hamadalneel Yousif B. , Maatoug Maha M. , Yousif Mirghani A.
Published: June 2023

BACKGROUND: Intravenous medications have greater complexity and require multiple steps in their preparation and administration, which is considered a high risk for patients. OBJECTIVE: To determine the incidence of intravenous medications preparation and administration errors in critically ill patients. METHODS: This was an observational, cross-sectional, prospective study design. The study was performed in Wad Medani Emergency Hospital, Sudan . RESULTS: All nurses working at the study setting were observed over nine days. During the study period, a total number of 236 drugs were observed and evaluated. The total error rate was 940 (33.4%), of which 136 (57.6%) errors with no harm, 93 (39.4%) errors with harm and 7 (3%) of errors associated with mortality. 17 different drug categories were involved, in which antibiotic was the highest error rate 104 (44.1%) and 39 different drugs were involved, in which metronidazole was the most drug involved 34 (14.4%). The total error rate was associated with nurse experience, OR (95% CI); 3.235 (1.834–5.706), and nurse education level, OR (95% CI); 0.125 (0.052–0.299). CONCLUSION: The study reported high frequency of IV medications preparation and administration errors. Nurse education level, and experiences were influenced the total errors.
Perception study of perceived value and social influence of digital health services in Indonesia
Authors: Panggabean Bungaran , Suharjo Budi , Sumarwan Ujang , Yuliati Lilik Noor
Published: June 2023

BACKGROUND: Healthtech has become a nascent sector of the internet economy since the emergence of the COVID-19 pandemic in 2020. Telemedicine features are facilitated, such as teleconsultation, e-diagnosis, e-prescribing, and e-pharmacy. However, the intention to use digital health services in Indonesia is still underdeveloped though the sales of other risk-free e-commerce products are high enough. OBJECTIVE: This study aims to assess the human perception of perceived value and social influences regarding the intention to use digital health services. METHODS: Google Forms web link is employed to disseminate a set of 4-Point Likert scale questionnaires. In total, 364 complete responses are collected. A descriptive approach is employed to process the data using Microsoft Excel and SPSS software. Validity and reliability are quantified using the item total-correlation method and Cronbach’s Alpha coefficient. RESULTS: Only 87 respondents (24%) ever used digital health services, of which Halodoc (92%) is the most preferred application, and teleconsultation became the most popular service to access. Out of four, the average score is 3.16 for perceived value and 2.86 for the social influence dimension. CONCLUSION: Most respondents, not dependent on user experience, perceive more values obtained using digital health services, such as time and money savings, convenience, flexible order time, undiscovered identity, adventurous experience, and enjoyment. Another finding of this research proves that some social influences from family, friends, and mass media also bring effect to amplify the intention to use. A low level of trust is assumed to be the cause of a small number of users.
Pengaruh Lingkungan Kerja, Self Efficacy, Work-Family Conflict dan Employee Engagement terhadap Mutasi Pegawai pada Dinas Perhubungan Kabupaten Dompu
Authors: Araffat Moh. Yassir , Putra I Nyoman Nugraha Ardana , Heriani Heriani
Published: June 2023

Tujuan penelitian ini adalah menganalisis pengaruh lingkungan kerja, self-efficacy, work-family conflict dan employee engagement terhadap mutasi pegawai di Dinas Perhubungan Kabupaten Dompu. Pendekatan sampel penelitian ini menggunakan pendekatan probabilitas (semua populasi dapat dijadikan sampel), dan digunakan 60 orang sebagai sampel. Instrumen penelitian berupa angket, dan sebelum digunakan untuk mengumpulkan data, terlebih dahulu dilakukan uji validitas dan reliabilitas, kemudian data dianalisis dengan menggunakan regresi linier berganda. Hasil penelitian menunjukkan bahwa: (1) lingkungan kerja berpengaruh negatif dan signifikan terhadap mutasi pegawai; (2). Self-Efficacy berpengaruh negatif dan signifikan terhadap turnover karyawan pada karyawan. (3) Work-Family Conflict berpengaruh positif dan signifikan terhadap mutasi pegawai pada pegawai. (4) Employee Engagement berpengaruh negatif dan signifikan terhadap turnover karyawan. (5) Lingkungan kerja merupakan variabel yang dominan mempengaruhi keinginan pegawai pindah kerja di Dinas Perhubungan Kabupaten Dompu.
Examining Malay Customary Marriage Law in the Malay Countries: An 'Urf Perspective
Authors: Saiin Asrizal , Karuok Mohamad Azmi , Hajazi Moh. Zaidi , Radiamoda Anwar M.
Published: June 2023

The purpose of this paper is to find out more clearly about the position of customary law for the Malay community, which can be said to be all Muslim, by analyzing it through the study of  ‘urf in Islamic law. This research is categorized as qualitative research. Qualitative research intends to understand the phenomenon of what is experienced by the research subject, for example, behavior, perception, motivation, action, and others, thoroughly and descriptively in a special natural context by utilizing the scientific method. The findings in this paper are that Malay customary marriage law, which has been practiced so far in Malay countries, is in accordance with Islamic law. The Malay customary marriage law that may be applied is a law that does not conflict with Islamic values, or 'urf al-sahih. Meanwhile, Malay customary marriage law that cannot be applied is a law that is contrary to Islamic values, or 'urf al-fasid, because it can damage the purpose of the shari'a to be passed down (maqashid shari'ah).
Legal Responses to Doping
Authors: Takayama Kanako , Hangartner Sena , Hajszan Jakob , Schnydrig Hanjo , Koch Patrick , Hayakawa Yoshihisa , Sugiyama Shoichi , Diethelm Dominique , Ege Gian , Claussen Malte C. , Gattiker Monika , Ishido Norihide
Published: June 2023

Doping in sports is a salient issue often discussed in the news, especially during major events such as the Olympics. However, there are still many uncertainties regarding the appropriate legal response. Because of the international nature of sport, there is great need for an in-depth comparative assessment and harmonized legal frameworks. The chapters included in this volume address doping related questions which were discussed at the Joint Workshop on Legal Response to Doping organized by the University of Zurich and the University of Kyoto. In the workshop, experts in the field of doping and sports law came together to analyze the existing antidoping regulations and laws with the objective to identify strengths and shortcomings of the current legal framework.
Comparisons of Silver Nanoparticle Synthesis Methods by Microwave and Non-Microwave using Hydrogen Gas as a Reducing Agent
Authors:   ,   Andrews University, Hanapin Sofia
Published: June 2023

Synthesis and characterization of silver nanoparticles are of current interest. This research project describes a simple and rapid synthesis of silver nanoparticles upon reduction of Silver (I) oxide (Ag2O) by molecular hydrogen (H2) at elevated temperature (70 – 100 °C) and a pressure of > 1 atmosphere by heating the aqueous mixture using a common kitchen microwave. This reaction generates naked silver colloids that contain no foreign stabilizers other than metal particles in aqueous media. Its application of an antibacterial effect was monitored by using biological cultures using the Kirby-Bauer Test.
Thermodynamic Analysis of PAMAM Dendrimer Synthesis
Authors:   ,   Andrews University, Jacobson Ryutaro
Published: June 2023

The objective of this research was to determine kinetic and thermodynamic data about the reaction between ethylene diamine and methyl acrylate which is used in the production of PAMAM dendrimers. Establishing a rate law and finding values such as rate constant, activation energy, and Arrhenius coefficient will help in determining the best possible conditions for the reaction. A rate law was established through the method of initial rates, comparing the rates of reactions with different initial concentrations to one another. Additional reactions were run with active cooling to observe the effects on rate and reaction progress, and finally reactions were run with varied reactant feed rates in order to test temperature controllability for future optimization work.
PENGARUH GAYA KEPEMIMPINAN TRANSFORMASIONAL MASA PANDEMI COVID-19 TERHADAP KEPUASAN KERJA PEGAWAI DI SAMSAT MEDAN SELATAN
Authors: Juliyanti Nur Azizah , Lubis Anggia Sari
Published: June 2023

The purpose of the study was to determine and analyze the Effect of the Covid-19 Transformational Leadership Style on Employee Job Satisfaction at the South Medan Samsat. Data research design, descriptive and quantitative. The population in this study is the total number of employees at the South Medan Samsat in 2021, amounting to 61 people. The sources of data in this study are primary data and secondary data. Where the primary data from observations, interviews and questionnaires. The data analysis technique used is descriptive analysis and simple linear regression. The results of simple regression analysis are Y=2,062+1,188X+e which shows that transformational leadership style has a positive and significant effect on employee satisfaction. while the results of the (t) test or partial test show that transformational leadership has a positive and significant effect. Regarding employee job satisfaction, it can be seen that the value of tcount =(24,458) > ttable (0,045). Then the coefficient of determination (R2) is 0.955 (95.5%). So it can be said that the variation of the dependent variable, namely transformational leadership in the model, can explain the variable job satisfaction of employees at Samsat Medan Selatan, while the remaining 0.045% is influenced by other variables outside the model.
CUSTOMER INTIMACY, CUSTOMERS EXPERIENCE, CUSTOMER SATISFACTION, CUSTOMER BONDING DAN CUSTOMER VALUE DALAM LOYALITAS NASABAH DI BANK SYARIAH
Authors: Vitram Khansa Lathifah , Rasa Muhammad Iqbal , Harto Suharto
Published: June 2023

Pada perkembangan perekonomian di Indonesia yang semakin maju, khususnya pada sektor perbankan syariah. Dengan pertumbuhan perbankan syariah di Indonesia telah menciptakan banyak investor dan nasabah dengan berbagai penghimpunan dana. Tingginya minat masyarakat terhadap perbankan syariah untuk menabung dan melakukan pembiayaan membuat sektor perbankan semakin prospektif. Dalam hal ini membuat persaingan dalam sektor perbankan syariah semakin kompetitif, terutama bagi bank syariah dengan segmen pasar yang sama, bank syariah mengalami peningkatan yang cukup signifikan dari tahun ketahun. Dari peluang tersebut banyak bank syariah diIndonesia berlomba-lomba bersaing guna untuk memenuhi kebutuhan nasabah. Dalam hal ini Bank syariah mempunyai peran penting yaitu untuk selalu memenuhi kebutuhan nasabah dengan menyediakan produk atau layanan yang beretika sesuai dengan prinsip-prinsip syariah dan menyediakan aksesibilitas ternyaman melalui berbagai sarana kapanpun dan dimanapun. Penelitian ini merupakan penelitian yang bertujuan untuk mengetahui pengaruh Customer Intimacy, Customer experience, Customer satisfaction, Customer Bonding dalam bank syariah.

Kata kunci : Customer Intimacy, Customer experience, Customer satisfaction, Customer Bonding,Costumer Value,  Bank syariah
Increasing Intensive Management of Goats in the Coastal City of Kendari
Authors: Hafid Harapin , Ananda Siti Hadrayanti
Published: June 2023

This activity is a community service activity carried out to help increase the productivity of goat selling breeders around the coast of Kendari City, especially in the Anduonohu Market area. Implementation of activities carried out in the form of counseling in the form of visits, delivery of material and discussions directly to goat farmer. The material presented was in the form of planting forage as the main source of feed for goats and using reinforcing feed, the need for strong and tidy goat pens, namely a stage model so that they can maintain environmental cleanliness and livestock health, Management of goat manure waste into bokashi fertilizer. The results of the activity show that they understand and are capable of cultivating forage as the main source of feed and know the importance of using forage boosters (concentrates). 2) Farmers know the benefits of using stilt pens to maintain a clean environment and goat health but have not implemented them due to limited funds to build cages. 3) Farmers do not know about the use of EM4 in leftover feed and livestock manure to produce bokashi organic fertilizer in a short time.
Cambiare paradigma per i disturbi del neurosviluppo? Dalla ricerca alla pratica clinica
Authors: Antonietti Alessandro , Borgatti Renato , Giorgetti Marisa
Published: June 2023

L'articolo-bersaglio propone alla comunità scientifica e ai clinici che operano nell'area dei disturbi del neurosviluppo una serie di questioni aperte relative al fare ricerca e al fare valutazioni diagnostiche. Le questioni scaturiscono dalle evidenze emerse dalle indagini delle neuroscienze e dal delinearsi di un diverso paradigma per comprendere i disturbi con esordio nell'età evolutiva. L'ampia eterogeneità che caratterizza le categorie diagnostiche dei disturbi del neurosviluppo ha favorito l'affermarsi di costrutti relativi alla complessità, alla multidimensionalità e alla comorbidità. Si fa riferimento all'approccio Research Domain Criteria (RDoC) che si propone come sistema diagnostico dimensionale con l'obiettivo di spostare il focus della ricerca e della pratica clinica lontano dalle esistenti categorie diagnostiche verso dimensioni del comportamento osservabile e misure neurobiologiche. La prospettiva transdiagnostica dell'approccio RDoc è qui utilizzata sia come possibile critica ai paradigmi di ricerca dominanti, sia come sfida per ripensare i disturbi del neurosviluppo e come potenziale soluzione per intercettare le specificità dei fenotipi.