bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical study of primary caesarean section among multigravida in a tertiary care hospital
Authors: Kumar Rajesh , Chaudhary Rachna , Dhama Vandana , Singh Shakun
Published: February 2023

Background: Primary caesarean section in multigravida refers to first time caesarean section in multiparous women who have had previous one or more vaginal delivery. The study focused on the frequency, indication, intra operative and postoperative complications, maternal and fetal outcome of primary caesarean section in multiparous women with previous vaginal deliveries.
Methods: It was a prospective study of all the cases of primary caesarean section in multigravida admitted at LLRM Medical College Meerut, Uttar Pradesh over period of 1 year from January 2021 to December 2021.
Results: Total number of deliveries during the study period of 1 year was 5670 and total no of caesarean section was 2432 with a caesarean rate of 42.89%. Out of 2432 caesarean section 488 (20.10%) were done  in primigravida and 253 (10.40%) in multigravida. In present study most common indication for caesarean section was malpresentation 68 (26.86%) followed by severe oligohydramnios in 47 (18.57%). Most common maternal complication was pyrexia in 24 (9.48%). Most common morbidity were due to preterm 65 (22.13%) neonates followed by RDS in 22 (8.69%) neonates.
Conclusions: Though responsible for least number of overall caesarean section, multiparous subjects undergoing primary caesarean section is high risk pregnancy with possibility of adverse obstetric outcome in significant number of subjects and hence multiparous women deserve the same attention during pregnancy and labour as primigravida and women with repeat caesarean section.
Improvement in the cases of hypertensive disorder of pregnancy with help of HDP-gestosis score
Authors: Imam Syeda Tuba
Published: February 2023

Background: An assessment tool for the risk of pre-eclampsia is the HDP-gestosis score, which has a range of scores from 1 to 3. A pregnant woman is classified as "at risk for pre-eclampsia" and treated appropriately if her overall score is 3 or higher. In order to predict pre-eclampsia, it is necessary to assess the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of the HDP-gestosis score.
Methods: From January 2022 to December 2022, 109 pregnant patients who presented at the obstetrics and gynaecology department were included in this prospective research. The patients' risk of developing pre-eclampsia was evaluated after 20 weeks of pregnancy. We collected information on the patient's age, gravida, obstetric history, menstrual cycle regularity, polycystic ovarian disease history, length of marriage, parity, prior medical and surgical intervention, prior/current pharmaceutical use, and family history. Gestosis score was determined and grouped into three risk categories: mild (score of 1), moderate (score of 2), and high risk (score of 3). For predicting the onset of pre-eclampsia, the HDP-gestosis score's sensitivity, specificity, PPV, NPV, and diagnostic accuracy were assessed.
Results: The mean age, gestational age, and BMI of the women were 25.71±5.9 years, 11.9±2.19 weeks, and 24.9±3.6 kg/m2, respectively. The gestosis score was 2 in 47.70% (n=52) of the participants, 1 in 38.53% (n=42), and ≥3 in 13.77% (n=15) of the women. Pre-eclampsia developed in 17.43% (n=19) participants. The sensitivity, specificity, PPV, NPV, and diagnostic accuracy of HDP-gestosis score for predicting pre-eclampsia were 86.66%, 96.49%, 86.91%, 97.98% and 96.12%, respectively.
Conclusions: Gestosis score is a brand-new early marker for pre-eclampsia development that enables patients to receive quick care, reducing the negative effects.
A clinical trial to assess the blood loss in women predisposed to postpartum hemorrhage with the use of prophylactic intravenous tranexamic acid
Authors: Satyasri K. , C. Chandana
Published: February 2023

Background: Postpartum hemorrhage (PPH), a complication encountered during third stage of labour, contributes to 25% of maternal death worldwide. Despite various measures for prevention and management of PPH, burden of PPH still looms.
Methods: Prospective randomized controlled clinical trial (RCT) was conducted in Vydehi Institute of Medical Sciences, among 128 patients predisposed to PPH, over 18 months. After meeting the inclusion and exclusion criteria, participants were randomized to receive tranexamic acid (TXA) intravenously 10 mg/kg along with 10 IU of oxytocin following the delivery. Patients were analysed for, blood loss, need for medical or surgical interventions.
Results: Parameters like age, mean gestational age at haemoglobin estimation, and at delivery were similar among groups. The need or parenteral iron, blood transfusions, uterine artery ligation and compression suture were higher in controls group, but not statistically significant. Among the cesarean section (CS) group, most significant pre-disposing factors for PPH were previous CS (p value=0.012) and anaemia (p value =0.01). Incidence of PPH 0.69% (p value =0.031) and use of additional uterotonics were statistically significant (p value <0.05). Among the vaginal delivery (VD) group, most significant pre-disposing factors were anaemia (p value =0.002), thrombocytopenia (p value =0.045), and fetal-macrosomia (p value =0.020). Incidence of PPH 0.25% (p value <0.001) and use of additional uterotonics and hospital stay were statistically significant.
Conclusions: We conclude that, anemic patients were at higher risk of PPH irrespective of the mode of delivery. Prophylactic TXA lowers incidence of PPH, blood loss, use of additional uterotonics and hospital stay even in the presence of pre-disposing factors. Quantification of blood loss is better estimated by drop in haemoglobin after 24 hours.
Prediction of metabolic syndrome by visceral adiposity index, lipid accumulation product and model of adiposity index amongst infertile women with and without polycystic ovary syndrome
Authors: Saxena Pikee , Gaur Jyoti , Mishra Archana , Jain Anju
Published: February 2023

Background: This study was conducted to compare visceral adiposity index (VAI), lipid accumulation product (LAP) and model of adiposity index (MAOD) for prediction of metabolic syndrome (MS) amongst infertile women with and without PCOS.
Methods: It was a case control, retrospective study performed in gynecology outpatient department of a tertiary care center. Total 143 infertile women with PCOS and 367 infertile women without PCOS were recruited in the study. Waist circumference (WC), BMI, waist hip ratio (WHR), insulin resistance, VAI, LAP, MOAD were assessed in both groups.
Results: Significantly higher values of WC, WHR, systolic BP, insulin postprandial and all 3 adiposity indices were found among infertile women with PCOS as compared to women without PCOS. In hormonal profile, testosterone, AMH, FSH, prolactin, estradiol was found to be significantly higher in PCOS group. For predicting MS in PCOS women, VAI had the highest AUC 0.878 with a cut off value of 3.1, highest sensitivity of 88.9%, specificity of 90.7%, positive and negative predictive value of 76.2% and 96% respectively followed by LAP and MOAD.
Conclusions: To conclude, all three adiposity indexes VAI, LAP and MOAD were significantly raised in PCOS women. VAI followed by LAP were the best indicators to predict metabolic syndrome in women with PCOS.
Fetomaternal outcome of women with thrombocytopenia in labour
Authors: Thakkar Palak , Desai Dhwani , Verma Ragini
Published: February 2023

Background: This study was conducted to study fetomaternal outcome in pregnancy with severity of thrombocytopenia.
Methods: It was a prospective observational study of fetomaternal outcome of women with thrombocytopenia admitted in labour room of a tertiary health care center of south Gujarat for 1-year period (April 2021-March 2022) after official approval from ethical committee. 100 consecutive consenting women with thrombocytopenia admitted in labour room of New Civil Hospital Surat were enrolled in this study.
Results: Mild thrombocytopenia was noted in 68% of the total cases, moderate thrombocytopenia in 27% and severe thrombocytopenia in 5% of cases. 59 subjects belong to age group of 20-25 years, 56 subjects were multipara, 70 subjects were registered antenatally, 68 subjects were delivered beyond 37 weeks of gestation. 48 subjects underwent LSCS and rest were delivered vaginally. 29 subjects had maternal complication. 95 subjects delivered alive baby of which 14 had NICU admission and 5 subjects had preterm still birth baby.
Conclusions: Thrombocytopenia is the second most common haematological finding in pregnancy next to anaemia. Majority of cases generally present at gestational age beyond thirty-seven weeks and belong to category of mild thrombocytopenia. Efforts should be made on improving antenatal registration, screening of maternal thrombocytopenia, early diagnosis and treatment.
Maternal and perinatal outcome in preterm premature rupture of membranes
Authors: R. Sudha , Biradar Priyanka
Published: February 2023

Background: Preterm premature rupture of membranes (PPROM) and preterm birth results in one third of perinatal mortality and maternal morbidity such as chorioamnionitis and abruption placenta and preterm caesarean section, Preterm premature rupture of membranes occurs in 3% of pregnancies. PPROM is associated with intrauterine infection. Early detection of intrauterine infection may help in prevent neonatal sepsis. Objective of present study was to analyse the maternal and perinatal outcome of PPROM patients between 28 to 36 weeks +6 days and predict intrauterine infection by access the level of C reactive protein to prevent chorioamnionitis and neonatal infection.
Methods: A descriptive study was conducted on 126 antenatal patients between 24 to 36 weeks+6 days with PPROM admitted to Department of Obstetrics and Gynaecology, Cheluvamba Hospital Mysore medical college, Mysore, Karnataka, India from February 2022 to July 2022. After establishing the diagnosis of PPROM patients were monitored and maternal and perinatal outcomes were studied.
Results: 24% patients had late PPROM. 63% of early PPROM latency period >24 hours and were managed conservatively till 34 weeks. 18% had chorioamnionitis in that 12% CRP positive status and immediate termination of pregnancy. 73% of newborns in this group needed admission due to complications of prematurity like RDS (54.54%). Perinatal mortality (2.12%) was due to sepsis. 80% of late PPROM had latency period 24 hours and sepsis was 36% in >24 hours and 10% in <24 hours.
Conclusions: The most common cause of perinatal mortality in early PPROM is prematurity and its complications. Hence conservative management to prolong pregnancy is recommended under strict monitoring for evidence of chorioamnionitis. C-reactive protein helps to pick up chorioamnionitis early. At the earliest evidence of chorioamnionitis termination irrespective of gestational age is warranted. In late PPROM, perinatal outcome is good. So, termination is advised as conservative management shall add to the fetal and maternal morbidity due to sepsis.
A comparative study of efficacy of two different regimens of vaginal misoprostol in first trimester termination of pregnancy in a tertiary care hospital
Authors: Ramya S. P.  , Gopalan Ushadevi
Published: February 2023

Background: Misoprostol has been authorised as an effective medication for termination of pregnancy at different gestations, cervical ripening, labour inducing in term pregnancy, and possibly therapy of postpartum haemorrhage in the last two decades. Objectives were to compare the efficacy of two different regimens of vaginal misoprostol in first trimester termination of pregnancy.
Methods: This was a randomized controlled trial conducted among 50 women in the reproductive age group with single live intrauterine gestation less than 12 weeks. All patients including both groups received mifepristone 200 mg oral administration as day 1 followed by group A received misoprostol 800 mg stat after 36 hours of mifepristone and group B received misoprostol 400 mg stat after 36 hours of mifepristone followed by 200 mg at 6 hourly 2 doses.
Results: The mean age of the study participants was 26.48±3.77 and 24.72±3.33 in group A and B respectively. The 20% and 16% in group A had repeat dose and dilatation and curettage (D and C) done whereas only 8% had D and C done in group B. There was no significant difference between the prevalence side effects between the groups. Group B showed higher dissatisfaction than group A. The 36% and 8% of the study participants in group A and B respectively had incomplete abortion.
Conclusions: Multidose regimen is found to be more effective in the first trimester termination of pregnancy than the single dose regimen.
Case report on perioperative management of combined factor V and VIII deficiency in a patient with prolapse uterus
Authors: Sree K. P. Bhavani , Rani G. Usha
Published: February 2023

Combined factor V and factor VIII deficiency is a rare autosomal recessive disorder with incidence of one in 10,00,000. We reported a case of seventy-one-year-old patient with third degree uterovaginal prolapse, diagnosed as combined factor V and VIII deficiency and the successful perioperative management during vaginal hysterectomy. With our experience in this, we conclude that for the patient's with factor V and VIII deficiency that the correction should be given for at least 2 weeks post operatively.
A rare case report on uterine perforation by levonorgestrel releasing intrauterine device
Authors: Vijaykumar C. R.  , Asha C.
Published: February 2023

A levonorgestrel-containing intrauterine contraceptive devices are widely used in contemporary gynaecology, primarily as an effective method for contraception and for control of menstrual disorders like menorrhagia and dysmenorrhea. A case report of the uterine perforation by the levonorgestrel-releasing intrauterine device (LNG-IUD) in a 33-year-old asymptomatic woman after an 18-month of insertion. On routine cervical smear examination, the LNG-IUD threads were not visualised through the cervical os. After abdominal ultrasound scan the confirmation of perforated LNG-IUD was done and was removed laparoscopically.
Case report of massive haemorrhage following medical miscarriage requiring uterine artery embolization
Authors: Sharma Jyotsna  , Sneha Murugesan , Pegu Bhabani , Rengaraj Sasirekha , Ajith Ananthakrishna Pillai  , Veena Pampampatti
Published: February 2023

Uterine arteriovenous malformations (AVM) are an abnormal, nonfunctional connection between uterine arteries and veins. These occur mostly after damage to uterine tissue following uterine surgical procedures. They may occur following even spontaneous abortion and resolve with expectant management without requiring a medical/surgical intervention. We report an interesting case of a woman who presented after medical abortion with uterine AVM with heavy bleeding requiring radiological intervention. Mrs. K, multiparous woman was referred in hypovlomeic shock from a district hospital. She had a medical abortion with Misoprostol at 9 weeks of gestation 2 months ago. No history of any curettage. She was stabilized and received appropriate transfusions. Sonography revealed a normal size uterus, with retained products of conception adjacent to a focal echogenic mass of size 5.8×4.6 cm in the posterior myometrium, with vascularity into and outward from the lesion suggestive of an AVM. The same was confirmed by CT angiography and an urgent uterine artery embolization (UAE) was undertaken. She withstood the procedure and recovered well. Anticipating spontaneous resolution of the retained products of conception, she was discharged home after clinical improvement and advised permanent method of contraception. Uterine AVM should be suspected in a woman who presents in child bearing age with heavy bleeding per vaginum following childbirth/abortion. Attempts of curettage may prove to be fatal in such scenarios. A high index of suspicion can help in an early diagnosis and seeking appropriate interventional assistance.
A rare case of genital myiasis in genital prolapse
Authors: Kumari Asha , Sudha Gandhi  , Savitri Verma  , Yukti Gaur  , Neeraj Chowdhary
Published: February 2023

Genital myiasis is an infestation by fly larvae in genital organs, where they feed and develop as parasites. They can cause severe infection, inflammatory reaction and can be linked to psychiatric disturbances. Commonly cutaneous, ophthalmic, auricular and nasopharyngeal myiasis are seen, with genital myiasis being a rare condition. We reported a case of an 82-year-old postmenopausal female who presented with the complaint of intense pain in genital region. After clinical evaluation she was clinically diagnosed as a case of genital myiasis of prolapsed uterus. Myiasis of the genital organ is a rare clinical entity. Good personal hygiene and proper sanitary conditions are very crucial for prevention of myiasis.
Pregnancy and COVID-19: an update
Authors: Soma Biswas
Published: February 2023

COVID-19 was identified in December 2019 in China. Previous research has suggested a potential link between COVID-19 and pre-eclampsia (PE). Therefore, it is crucial to comprehensively evaluate the clinical symptoms and laboratory results of these conditions. This narrative review was conducted in light of the limited understanding of how COVID-19 affects pregnant women and its association with pre-eclampsia. It is important to note that these two conditions may share similar features that can influence the outcome of pregnancy.
T. WARTON AND J. RITSON LITERARY DEBATE OVER HISTORICAL TRUTH IN THE AGE OF ENLIGHTENMENT
Authors: Kolosova Ekaterina I.
Published: February 2023

The appeal to early and medieval poetry became one of the keys to rethinking the origins of national culture for British historians, antiquarians, textologists and writers of the XVIII century. This article examines the literary debate of English writer and textual critic Joseph Ritson with his colleague Thomas Wharton, author of “The History of English Poetry”, three volumes of which were published in 1774–1781. Since by the middle of the XVIII century, the history of the English language and literature has not yet received the status of a research discipline; in the process of studying ancient manuscripts, antiquarians put forward a variety of hypotheses that could explain the emergence of national art. Being an experienced researcher of antiquity, Ritson was well acquainted with the literary texts, that Wharton wrote about in his “History”, and could not approve his critical revision of AngloSaxon art for the formation of British culture. The debate between Ritson and Wharton can be seen as a dispute between two literary critics, in which each defends his own view on the development of the English language and poetry. On the other hand, in his “Observations” Ritson appears as a textual scholar and a rival of Wharton. In his works, he is intolerant of factual inaccuracies, loose assumptions and incorrect interpretations: Wharton’s irresponsible work is considered misleading and posing a great intellectual danger to the reader.
THE FUNERAL OF N. KONONOV’S NOVEL BY LITERARY CRITIQUE (ABOUT THE RECEPTION OF “THE FUNERAL OF A GRASSHOPPER”)
Authors: Govorukhina Yulia A.
Published: February 2023

The article is devoted to the problem of production of the book value, faith in its value, carried out by literary critique as an Institute of the literary field. The material is the critical reception of Nikolai Kononov’s novel “The Funeral of a grasshopper”. Published in 2000, the novel gets the small Apollon Grigoriev’s Award (not the big one) and is included in a short list of The Russian Booker Prize, but does not win. The aim of the research is to study the role of critique in the fate of the Kononov’s novel. According to the author of article, literary critique has generated interest in the work of the writer, and has “buried” it. The methodological basis of the work is the position of receptive aesthetics and sociology of literature. The author studies pragmatic strategies of both positive and negative critique of the novel: giving the book the status of exclusive (in terms of content, poetics, produced effect) or banal text. The author concludes that the positive critique devoted to the novel is wordy, metalogical (the criticism is infected by Kononov’s style), often turns into a retelling. Negative critical judgment, the accusations of lack of originality and the banality of the idea, also contributed to the novel’s “funeral” and undermined the symbolic value of the text.
Wykorzystanie cnót w działalności dydaktyczno-wychowawczej nauczyciela akademickiego
Authors: Polok Grzegorz , Kapias Michał
Published: February 2023

Prestige of academic teacher’s activities and his or her authority, should most of all result from moral attitude. Thus there is need in this kind of activity to use ethic virtues. Thanks to them human improves internally, but also can realize the concrete property outside. Virtues are necessary for person both for him or her as an average human being and also as a scholar and an educator. By setting own example one can have the most influence on students’ moral attitudes. Consequently an occasion arises to improve cardinal classic virtues, which include: prudence, deliberation, justice and courage, but also in the virtues that are related to them. These activities drive to form yourself in giving good example and have a huge impact on academic environment’s advancement.
Etyka pracy leśnika w latach 1918–1939 na terenie Wielkopolski w świetle materiałów archiwalnych
Authors: Kowalski Piotr
Published: February 2023

Ethical principles concerning foresters were presented in this article in the light of the forest law passed in the interwar period for the whole country, as well as in the light of the documents issued by the local forest administration. For analysis were submitted especially archive documents on foresters’ responsibility for forest goods: wood and game. Ethical attitude of foresters translated, among other things, into efficient functioning of forest management all over Greater Poland.
Źródła etyki doradztwa w filozofii starożytnej
Authors: Mrówka Małgorzata
Published: February 2023

Advising is an important area of human activity, it helps to clarify own experiences and thoughts, increases self-awareness and competence, leads to well grounded decisions and choices. In modern times advising gained even more importance as it has successfully became a part of a business world. This very practical aspect of advising significantly influences development of technology, management methods and organization of human work, while at the same time it may lead to problems and risks of economical, political or ecological nature. Hence advising should be supported by philosophical consideration and ethical assessment – this is even more so, as advising in it’s theoretical, methodological and ethical foundations is well grounded in philosophy. Main perspectives of reflection on advising are driven by traditional philosophical questions and disputes. Historical research shows that many virtues are of stable properties that last across ages. Thus, drawing on experience of philosophers-advisors from Sophists, Socrates, Plato, Aristotle and Seneca we see that practical philosophy can give support in solving different problems of business advisory and can help in drawing professional code rules of advisor.
Materialismo y arte en Walter Benjamin
Authors: Sarasola Beñat
Published: February 2023

El presente artículo analiza la cuestión del materialismo y su relación con el arte en el pensamiento de Walter Benjamin. Es una cuestión harto controvertida en los debates sobre Benjamin, y el artículo estudia minuciosamente sus dos textos fundamentales que abordan la cuestión: El autor como productor y La obra de arte en la era de su reproductibilidad técnica. Antes de ello, se enmarca el problema en el contexto de la época y, en especial, en la relación de Benjamin con Brecht, que fue tomado como uno de los elementos clave para entender el giro materialista del primero. Este hecho perturbó algunos de los colegas como Adorno, Horkheimer y Karplus, que veían a Brecht como un materialista excesivamente ortodoxo. El artículo defiende que si bien Benjamin giró hacia posiciones materialistas a lo largo de la década de los 30, ese materialismo no era como la de la ortodoxia marxista de la época, aunque, efectivamente, fue más allá de los planteamientos modernistas de Adorno.
Rural banks' financial contributions to agriculture, health, and education (AHE), and their impact on the Ghanaian economy
Authors: Arhin Solomon
Published: February 2023

The rural banks have become a growing and vibrant part of the whole banking industry and the Ghanaian economy as a whole. This study sought to assess the activities of rural banks and their contribution toward the economic development of Ghana in what the researcher described as a triangular model (AHE): Agriculture, Education, and Health. The sample consisted of 339 employees including senior members from 15 rural banks. The data for the study were collected with a questionnaire. The findings revealed that rural banks had performed well as far as the triangular model (AHE) is concerned in the localities in which they have been established and the country as a whole. The study recommends that rural banks have to be carefully monitored by policymakers to yield maximum benefits to consumers.
Descripción de algunos métodos de solución de ecuaciones algebraicas de tercer y cuarto grado en una variable: una reseña histórica
Authors: Barrantes González Héctor
Published: February 2023

El objetivo del presente trabajo es realizar una exposición detallada de la resolución por radicales de las ecuaciones de grado tres y cuatro en una variable, utilizando diversos métodos. En el caso de la ecuación de tercer grado, se describen los métodos de Niccolo Fontana (Tartaglia) y Girolamo Cardano, quienes fueron los que dieron la solución de dicha ecuación, con coeficientes positivos.También se analiza la ecuación general de tercer grado es decir, con coeficientes reales y se detalla el método para hallar todas las soluciones reales y complejas. Se describe además el método de François Viète, para un caso particular de la ecuación de grado tres. Para la ecuación de cuarto grado con coeficientes reales, se describe el método de Ludovico Ferrari y el método de René Descartes. Además, se ilustran los métodos con ejemplos detallados.
Romiplostim in Eltrombopag Refractory Thrombocytopenia Post Bone Marrow Transplant in a Child with MDS: A Case Report
Authors: Malaeb Farah , Abboud Miguel R
Published: February 2023

Thrombocytopenia is a well-known complication post bone marrow transplant, whether primary or secondary. Refractory thrombocytopenia is not uncommon and over the past few years, thrombopoietin receptor agonists have emerged as new agents for the management of the above. Namely Eltrombopag and more recently Romiplostim. In children however, though Eltrombopag is being more frequently used, Romiplostim usage is still rarely reported for management of thrombocytopenia post bone marrow transplantation. Our experience with Romiplostim was successful in the management of refractory thrombocytopenia in a child with MDS post bone marrow transplantation.
A THEORETICAL APPROXIMATION FOR LAMINAR FLOW BETWEEN ECCENTRIC CYLINDERS
Authors: OGRETİM Egemen , ÇAKMAK Hasan
Published: February 2023

Taylor-Couette flow between two concentric cylinders has received much attention due to its use in various applications, including biomedical devices, micro electro-mechanical systems, polymer pumping and electric motor cooling. Due to the complex interaction of the viscosity and the involved geometry within the confined space, different flow regimes are dominant under different conditions, affecting the fluid dynamics and heat transfer. In analyzing the mentioned flow, besides the experimental and computational studies, analytical models have been developed with varying levels of complication. In the present study, using the homotopy of both the flow and the domain geometry between the concentric and eccentric cylinders, a practical formula for flow between eccentric cylinders is developed. In doing so, an appropriate transformation function for the geometry is developed and embedded into the velocity equation for the concentric cylinders. The resultant equation is tested against flow simulation results. A validity margin analysis is performed based on the variation of the mass flow rate between the cylinders. It is seen that the proposed model for eccentric cylinders is applicable for all gap distances, unlike the previous models that are restricted to narrow gaps. Finally, a separate formula to quantify the error in the estimates of the present method is also derived, which involves the ratio of the cylinders and the eccentricity.
OPTICAL CHARACTERIZATION of STEARIC ACID POWDER and ITS USE for THE SYNTHESIS of NANOPARTICLES
Authors: ALLAHVERDİ Çağdaş
Published: February 2023

Fatty acids are found in the structure of triglycerides and phospholipids which have vital importance for the life. Stearic acid is an important member of the fatty acids. It is used in the manufacturing of various products such as soaps, detergents, and rubbers. It is valuable to provide a thermal and optical characterization database of stearic acid. In this study, a comprehensive database has been prepared by studying thermogravimetric analysis, X-ray powder diffraction, dispersive Raman and Fourier transform infrared spectroscopies of stearic acid. Its thermal decomposition temperature, X-ray diffraction angles and infrared vibrational modes have been determined. Stearic acid has been used at the synthesis of cadmium selenide quantum dots, bismuth nanoparticles and mixed copper/zinc nanocrystals. Hot-injection and one-pot synthesis methods have been utilized to synthesize these nanostructures. Their sizes, distributions, shapes, elemental compositions, and crystalline structures have been investigated by transmission electron microscopy and energy dispersive X-ray analysis. Mixed copper/zinc nanocrystals have also been examined by X-ray diffraction spectroscopy.
DENSITY FUNCTIONAL THEORY INVESTIGATION ON DRUG-DRUG INTERACTIONS: ESCITALOPRAM AND SALICYLIC ACID
Authors: DABOE Musa , PARLAK Cemal , ALVER Özgür
Published: February 2023

Each year many new possible drugs have been introduced in the hope of the solution to many different medical problems or diseases. Further, many people around the world suffer from more than one health problem at a time. It is also known that some drugs are prescribed as combinations of several other drugs at once. In this study, taking the advantage of density functional theory, we have investigated the possible outcomes if someone uses escitalopram and salicylic acid at once. The obtained findings suggest that following the interaction activity of drugs is possible to change. Therefore, special care is required when using these drugs together.
DFT CALCULATIONS IN MONOMERIC AND DIMERIC FORMS OF N-BENZYLMALEIMIDE (NBM) COMBINED WITH VIBRATIONAL SPECTROSCOPIC PARAMETERS
Authors: ARI Hatice
Published: February 2023

The structural, vibrational and theoretical analyses of N-benzylmaleimide (NBM) having chemical and biological significances have been made. The four possible conformers and their sixty-six dimeric forms linked by the intermolecular C=O···H hydrogen bonding were investigated for the stability. The conformational and the dimeric structures of NBM in the gas phase were investigated and the population distributions of the conformations and dimers were obtained using the Boltzmann distribution. The experimental IR and Raman spectra of solid phase NBM were recorded, and the bands were compared with the theoretical wavenumber the values of the monomer and the dimer forms for their assignments. The new scale factors (0.9617 for B3LYP/6-31G(d) and 0.9531 for M06-2X/6-31G(d)) obtained for NBM can be used more accurately in vibration calculations of all maleimide derivatives. The Molecular Electrostatic Potential (MEP) map showed that the negative and the positive regions have changed from monomeric to dimeric form changes, while the HOMO-LUMO shapes did not generally change in monomeric and dimeric forms. The nucleophilic and electrophilic Fukui functions and dual descriptors shows that maleimide and benzyl groups are nucleophilic and electrophilic regions, respectively, additionally the dual descriptor values decrease upon dimerization.
Coğrafya Bölümü Öğrencilerinin Beyin Göçü Algıları: Bir Metafor Çalışması
Authors: ŞAHİN Vedat , İNCE Ziya
Published: February 2023

Dünyanın küreselleşmesiyle birlikte günümüzde beyin göçü artarak devam etmektedir. Beyin göçüne katılan insanların çoğunluğunun yetiştikleri yerler üniversitelerdir. Diğer yandan beyin göçü kapsamında yurt dışına yerleşmiş olan bazı insanların çeşitli nedenlerle ülkelerine dönmeleri veya irtibatlarını devam ettirmeleri önemlidir. Dolayısıyla beyin göçü sebebiyle kaybedilen insanların, kazanılması için farklı iş birliği yollarının aranması gerekmektedir. Bu çalışmada üniversite öğrencilerinin beyin göçüne yönelik yaklaşımları metafor yoluyla araştırılmıştır. Araştırmada Tekirdağ Namık Kemal Üniversitesi coğrafya bölümü öğrencilerinden 135 kişi katılımcı olarak yer almıştır. Bu çalışma nitel araştırma yönteminde ve olgu bilim modelde bir form aracılığıyla verilerin toplanmasıyla gerçekleştirilmiştir. Çalışma bulgularına göre öğrenciler ülke bazında beyin göçü için en fazla ABD metaforunu kullanmışlardır.
Talar body and posterior talar process fracture combined with peritalar luxation (clinical case)
Authors: Zatsepin V. A. , Novikov S. V. , Panin M. A. , Aliev R. N. , Prokhorov A. A.
Published: February 2023

The uniqueness of this clinical case is due to a rare combination of peritalar luxation of the talus with a fracture of its body and posterior process. No description of the same clinical case was found in the literature, however, it has been proven that such injuries have an unfavorable prognosis and are fraught with multiple complications. Also, the limited information associated with the low incidence of this type of severe injury puts practitioners in front of the difficulties of diagnosis and treatment. A 35-year-old man was injured while playing basketball. Upon admission, computed tomography (CT) revealed a fracture of the body of the talus with displacement of the distal fragment and its dislocation in the talonavicular, subtalar and talo-tibial joints, as well as a fracture of the posterior process of the talus. After an unsuccessful attempt at closed reduction, open removal of the dislocation and reposition of fragments were performed, followed by osteosynthesis of the fracture of the body of the talus. In the postoperative period, additional immobilization in the ANF was performed, followed by replacement with a functional orthosis. 6 months after the injury, the patient restored the level of his daily activities almost completely, the control CT showed no signs of post-traumatic arthrosis of the subtalar and ankle joints, how-ever, there were signs of the development of partial aseptic necrosis of the talus. This injury is unique, and despite its severity, the use of the correct treatment tactics can provide a satisfactory clinical and functional outcome.
Cytomegalovirus and Herpes Simplex Virus Co-Infection: Recurrence in a Kidney Transplant Recipient
Authors: Santos Maria Beatriz , Rodrigues Gonçalves Ana Catarina , Maltez Fernando
Published: February 2023

N/a.
The acceptance and effectiveness of digital learning technologies: A detailed empirical investigation in Islamic study classrooms
Authors: Mazrur  , Jennah Rodhatul , Mujib Abdul , Jamalie Zulfa
Published: February 2023

The acceptance of different technologies in different classroom settings has been addressed in the current study. Integrating alignment theory with the Technology Acceptance Model (TAM), this study investigates the predictive differences between the use and adoption of four technologies. The technologies were used in Islamic study classrooms for four months during the spring semester of 2022 among the students of the Palangkaraya state Islamic religious institute in Indonesia. The survey questionnaire was distributed among students at the end of the semester. The results of this study revealed students' behavioral intentions to use all four digital technologies. However, the impact of adopting the classroom response system was larger followed by digital textbooks, mobile virtual reality and classroom chats. These results depict that students prefer the classroom response system and have little preferences for classroom chats while learning Islamic studies. The favorable results for the classroom response system, digital textbooks and mobile virtual reality depict that practitioners should consider the ease of access and affordability of these technologies at all educational levels to enhance students' learning capabilities.
Management of soft tissue defects of the thumb
Authors: Van Hove Bram , Del Piñal Francisco
Published: February 2023

Hand surgery has undergone substantial changes in recent years, especially for reconstructive surgery techniques. We discuss the management of soft tissue defects of the thumb, discussing indications, and operative pearls and pitfalls. We cover non-operative treatment and local advancement flaps for small distal soft tissue defects and pedicled flaps for more significant defects. We also discuss composite vascularized free flaps such as second-toe neurocutaneous flaps and partial hallux transfer for compound defects or total amputations. This article aims to provide hand surgeons with an update on reconstructing an injured thumb.
Use of mHealth for management of hypertension in low and middle-income countries: opportunities and challenges
Authors: Bhandari Buna , Neupane Dinesh , Thapa Poshan , Pradhan Pranil Man Singh
Published: February 2023

Despite being the leading cause of global mortality, the hypertension control rate is astonishingly low, particularly in low- and middle-income countries. There is evidence that the mHealth approach is a potential platform for delivering interventions for hypertension management. Our recent study from Nepal also provided strong evidence for reducing blood pressure, improving control rate, and medication adherence. The objective of this paper is to document the real-world experience of designing and implementing a mHealth project in Nepal and relates them with the evidence from other similar Low- and Middle-Income Country (LMIC) settings. We learned that mHealth provides a unique opportunity to bridge the gap between providers and patients, send health education and reminder messages, secure patients' privacy, and make data management easier. We also encountered technological and financial barriers, unclear mHealth policy and guidelines, and low literacy levels, including digital literacy. As many of them are addressable, integrating mHealth provides a promising approach to hypertension management.
Obstructive Sleep Apnea as a Cause of Gout
Authors: Abrams Burton , Delannoy Peter , Johnson Richard
Published: February 2023

Gout is not only associated with obstructive sleep apnea (OSA), but the intermittent episodes of hypoxia that occur with OSA may also have a role in causing gout. Epidemiological studies have documented a higher incidence and prevalence of gout in individuals diagnosed with OSA than in individuals never diagnosed with OSA. The pathophysiology of OSA’s chronic episodes of hypoxia leading to hyperuricemia and gout involves boththe overproduction and underexcretion of uric acid. Treating OSA may be an additional way to control gout and its life-threatening comorbidities. Clinicians are urged to evaluate their patients with hyperuricemia/gout for OSA as it may lead to alternative ways to control gout with superior outcomes that simply pharmacologic treatment alone.
Gauge Symmetry and Invariant Features of Particles and Photons: Insights into Duality, Time’s Arrow and Nonlocality
Authors: Klevgard Paul
Published: February 2023

Particles and photons appear to be total opposites; the former has rest mass which requires space to exist; the latter has kinetic energy which requires time to occur (oscillate). But they do share certain properties (e.g., quantization) that remain invariant when one is transformed (swapped) for the other. This gauge invariance is developed in some detail.The symmetry between particle and photon turns out to be one of inversion. It is the equalities of special relativity that support this inversion and the accompanying invariances: mass transformed to energy; space transformed to time. The great advantage of these symmetries (inversions) is that they provide guidance for an object little understood (the photon) based upon an object well understood (the particle). On this basis, progress can be made in the understanding of some long-standing issues: wave-particle duality, time’s arrow, the constant speed of light and nonlocality.
Pelaksanaan Pemungutan Retribusi Terminal di Kabupaten Sukoharjo
Authors: Ambarwati Rezi Budiningtyas , Waluyo Waluyo
Published: February 2023

This Research Aims To Determine The Implementation Of The Collection Of Type C Terminal Levies In Sukoharjo Regency As Well As The Supporting And Inhibiting Factors In The Implementation Of Type C Terminal Levies Collection In Sukoharjo Regency. This Research Was A Normative Or Doctrinal Legal Research With A Statutory Approach And A Conceptual Approach. The Type Of Data Used Is Primary Data And Secondary Data. The Techniques Used In Gathering Legal Materials In This Research Was Interviews And Literature Studies Or Documents. This Research Uses Analytic Syllogism Method Of Deductive Thinking. The Results Of This Reasearch That The Implementation Of Terminal Cost Collection Is In Accordance With Existing Regulations, But There Are Some Obstacles That Cause Terminal Costs Do Not Match The Expected Target.
Pelaksanaan Perlindungan Lahan Pertanian Pangan Berkelanjutan Berdasarkan Regulasi Rencana Tata Ruang
Authors: Oktiana Ulfa Nur , Waluyo Waluyo , Nugroho Asianto
Published: February 2023

This study aims to determine the implementation of sustainable food agriculture land protection in Sleman Regency based on Regional Regulation No. 12 of 2012 concerning the Sleman Regency Regional Spatial Plan 2011-2031, as well as the obstacles of the Sleman Regency Government in establishing Sustainable Food Agricultural Land Protection Areas. This research is an empirical study. The data source used in this study came from primary data, which were the results of interviews with Civil Servants in the Agriculture and Fisheries Office of the Sleman Regency and the Sleman Regency Regional Development Planning Agency. Supported by secondary data consisting of primary legal materials and secondary legal materials. The results of research related to the implementation of sustainable food agriculture land protection in Sleman Regency shows that the spatial regulation of the Sleman Regency is only limited to efforts to control land conversion as a protection effort, there has been no determination of sustainable food agriculture areas due to various obstacles. In the implementation of the spatial planning policy is not enough to control the rate of conversion of agricultural land.
Tinjauan Yuridis Kewenangan Badan Keamanan Laut dalam Menjaga Keaman Laut
Authors: Ramadhan Alfin , Winarno Djoko Wahju
Published: February 2023

This study aims This study aims to determine and analyze the role of the Maritime Security Agency in maintaining maritime security of the Republic of Indonesia based on Law Number 32 of 2014 concerning Maritime Affairs. This legal research is included in normative legal research, which is perspective by using sources of legal materials, both primary and secondary legal materials. The legal material collection technique used is by means of library research in the form of books, regulations, and other research documents as well as for supporting legal materials conducted interviews with the Sea Security Agency. The technical analysis of legal materials used by the writer is deduction technique based on deductive reasoning methods. Based on the results of research and discussion, it can be concluded that Bakamla as a marine security institution replaces the function of the sea security coordination agency which is still considered ineffective. Bakamla has duties in security and safety patrols in the territorial waters and jurisdictions with the authority of one of them in the form of instant pursuit, stopping, capturing and inspecting ships to be handed over to the relevant ministries and agencies. To carry out these duties and authorities, a legal action unit was formed which is representative of ministries and institutions that have authority in the field of law enforcement at sea. But there are still some obstacles in the exercise of authority both in terms of facilities and infrastructure and there are overlaps with several other institutions that are also authorized to enforce law at sea.
Pelaksanaan Pengawasan dan Penegakan Hukum Izin Usaha Toko Swalayan Oleh Dinas Perdagangan Kabupaten Sukoharjo
Authors: Andriyani Endah , Raharjo Purwono Sungkowo , Subekti Rahayu
Published: February 2023

This study aims to determine the implementation of supervision and law enforcement of minimarkets conducted by the Department of Commerce, Cooperatives, Small and Medium Enterprises Sukoharjo. This research is prescriptive normative legal research. This research uses primary and secondary legal material sources as well as data collection techniques using the legislative approach method. The data analysis technique in this study uses the syllogistic deduction method. This research shows that the supervision of minimarkets is carried out regularly and specifically. Periodic monitoring is carried out in accordance with plans that have been carried out. Supervision is specifically carried out when the Department of Trade, Cooperatives, Small and Medium Enterprises get a report from the public and related agencies. Law enforcement is carried out by giving verbal warnings, warning letters up to three times, until the closure of the business.
Perlindungan Hukum Bagi Pemegang Sertifikat Hak Atas Tanah Dalam Kasus Sertifikat Ganda
Authors: Ayuningtyas Annisa Shafarina , Candrakirana Rosita , Najicha Fatma Ulfatun
Published: February 2023

This study discussing about the factors that causing the emergence of a double certificate and how agrarian law in Indonesia provides legal permission for certificate of land rights holder. This research is a normative legal research that acts prescriptive. The approach that used in this research are case reporting (case approach) and accessing the law (statute approach). Sources of data obtained from primary, secondary and tertiary legal materials. From the research results it is known that the factors of double certificate are inaccuracy of National Land Agency in the process of certificates issuance. Double certificate causes legal uncertainty for holders of land rights, thus potentially causing disputes in the future which also causing loss for both of holders. Legal protection obtained by the holders of land rights that are harmed because of the existence of double certificate are cancellation and revocation of related documents that are considered harmful by National Land Agency.
Pelaksanaan Perlindungan Kesehatan dan Keselamatan Kerja Terhadap Pekerja Perseroan Terbatas
Authors: Utomo Jalu Ario Setyo , Karjoko Lego
Published: February 2023

This research is come from the importance of human resources in doing work. The factor that easily affects human resources in terms of production is Occupational Health and Safety (K3). Factors that influence the implementation of Occupational Safety and Health (K3) at PT. Halo Indonesia Manufacture, namely personal protective equipment (PPE), warning signs, human resources (HR) and technology.  The implementation of Occupational Safety and Health (K3) at PT. Halo Indonesia Manufacture, namely establishing an Occupational Safety and Health Management System (SMK3), preventing and reducing accidents, extinguishing fires, providing aid in accidents, providing personal protective equipment to employees and providing training on work safety.