bluuebunny/crossref_metadata_2025 huggingface dataset:
A logic of defeasible argumentation: Constructing arguments in justification logic
Authors: Pandžić Stipe
Published: December 2020

In the 1980s, Pollock’s work on default reasons started the quest in the AI community for a formal system of defeasible argumentation. The main goal of this paper is to provide a logic of structured defeasible arguments using the language of justification logic. In this logic, we introduce defeasible justification assertions of the type [Formula: see text] that read as “ t is a defeasible reason that justifies F”. Such formulas are then interpreted as arguments and their acceptance semantics is given in analogy to Dung’s abstract argumentation framework semantics. We show that a large subclass of Dung’s frameworks that we call “warranted” frameworks is a special case of our logic in the sense that (1) Dung’s frameworks can be obtained from justification logic-based theories by focusing on a single aspect of attacks among justification logic arguments and (2) Dung’s warranted frameworks always have multiple justification logic instantiations called “realizations”.

We first define a new justification logic that relies on operational semantics for default logic. One of the key features that is absent in standard justification logics is the possibility to weigh different epistemic reasons or pieces of evidence that might conflict with one another. To amend this, we develop a semantics for “defeaters”: conflicting reasons forming a basis to doubt the original conclusion or to believe an opposite statement. This enables us to formalize non-monotonic justifications that prompt extension revision already for normal default theories.

Then we present our logic as a system for abstract argumentation with structured arguments. The format of conflicting reasons overlaps with the idea of attacks between arguments to the extent that it is possible to define all the standard notions of argumentation framework extensions. Using the definitions of extensions, we establish formal correspondence between Dung’s original argumentation semantics and our operational semantics for default theories. One of the results shows that the notorious attack cycles from abstract argumentation cannot always be realized as justification logic default theories.
Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer’s Coordinating Center Participants
Authors: Wang Ge , Li Wei
Published: December 2020

Background:

It is inconclusive on how sex affects the risk of developing mild cognitive impairment (MCI) or dementia.

Objective:

To investigate how sex affects the risk of developing MCI or dementia.

Methods:

A secondary data analysis was performed on data collected from participants enrolled at Alzheimer’s Disease Research Centers funded by National Institute on Aging. There were two inclusion criteria: 1) participants were free of dementia at the baseline visit; 2) every participant must have at least one follow-up visit. A Cox proportional hazards model was used to investigate how sex affects the risk of developing cognitive impairments.

Results:

During a follow-up period of more than 10 years, male participants had a slightly higher incidence than female participants for either MCI or dementia. Not surprisingly, a higher prevalence was observed in male than female participants for either MCI or dementia. However, male participants had a higher mortality rate than their female counterparts.

Conclusion:

The male sex is associated with a higher risk for developing cognitive impairments along the aging process.
Optimal decay of an abstract nonlinear viscoelastic equation in Hilbert spaces with delay term in the nonlinear internal damping
Authors: Chellaoua Houria , Boukhatem Yamna , Feng Baowei
Published: December 2020

In this paper, we consider a second-order abstract viscoelastic equation in Hilbert spaces with delay term in the nonlinear internal damping and a nonlinear source term. Under some suitable assumptions on the weight of the delayed feedback, the weight of the non-delayed feedback and the behavior of the relaxation function, we establish two explicit and general decay rate results of the energy by introducing a suitable Lyaponov functional and some properties of the convex functions. Moreover, we give some applications and examples. This work generalizes the previous results without time delay term to those with delay in the nonlinear damping.
LncRNA XIST/miR-137 axis strengthens chemo-resistance and glycolysis of colorectal cancer cells by hindering transformation from PKM2 to PKM1
Authors: Zheng Hailun , Zhang Mei , Ke Xiquan , Deng Xiaojing , Li Dapeng , Wang Qizhi , Yan Shanjun , Xue Yongju , Wang Qiangwu
Published: December 2020

BACKGROUND: Glycolysis was an essential driver of chemo-resistance in colorectal cancer (CRC), albeit with limited molecular explanations. OBJECTIVE: We strived to elucidate the involvement of lncRNA XIST/miR-137/PKM axis in chemo-tolerance and glycolysis of CRC. METHODS: Altogether 212 pairs of tumor tissues and adjacent normal tissues were collected from CRC patients. Moreover, human CRC epithelial cell lines, including HT29, SW480, SW620 and LoVo, were purchased in advance, and their activity was estimated after transfection of si-XIST or miR-137 mimic. Furthermore, 5-FU/cisplatin-resistance of CRC cells was determined through MTT assay, and glycolytic potential of CRC cells was appraised based on oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). RESULTS: Highly-expressed XIST were predictive of severe symptoms and unfavorable 3-year survival of CRC patients (P< 0.05). Besides, silencing of XIST not only diminished proliferative, migratory and invasive power of CRC cells (P< 0.05), but also enhanced sensitivity of CRC cells responding to 5-FU/cisplatin (P< 0.05). Glycolytic potency of CRC cells was also undermined by si-XIST, with decreased maximal respiration and maximal glycolytic capacity in the si-XIST group as relative to NC group (P< 0.05). Nevertheless, miR-137 mimic attenuated the facilitating effect of pcDNA3.1-XIST on proliferation, migration, invasion, 5-FU/cisplatin-resistance and glycolysis of CRC cells (P< 0.05). Ultimately, ratio of PKM2 mRNA and PKM1 mRNA, despite being up-regulated by pcDNA3.1-XIST, was markedly lowered when miR-137 mimic was co-transfected (P< 0.05). CONCLUSIONS: LncRNA XIST/miR-137 axis reinforced glycolysis and chemo-tolerance of CRC by elevating PKM2/PKM1 ratio, providing an alternative to boost chemo-therapeutic efficacy of CRC patients.
Different perceptions, different open government strategies: The case of local Mexican public managers
Authors: Sandoval-Almazán Rodrigo , Criado J. Ignacio , Ruvalcaba-Gómez Edgar A.
Published: December 2020

Open government has become a research trend among e-government scholars around the world. However, most research in this field has focused on national policies and the implementation thereof. Typically, this is related to Open Government (OG) ecosystems, data, policies and models, yet very little attention has been paid to the most basic level: the municipal/local level. The purpose of this research paper is to fill this gap. We based our research on an instrument for the assessment of OG priorities in Spanish municipalities (Gómez, Criado, & Gil-Garcia, 2017a). This instrument for assessment was adapted to Mexican municipalities. In so doing, we surveyed 67 cases of Mexican public officials working on OG or in transparency offices in municipalities across Mexico during 2017. This paper reports the findings of this exploratory research, grouping concepts of perception, and analyzing four elements of OG: 1. Open Government; 2. Transparency; 3. Citizen Participation and 4. Open Data. Going forward, we used factor analysis to group concepts and identify two principal perspectives for addressing OG policy implementation in local governments, one oriented at fostering technological innovation, and another at promoting democratic values of co-responsibility. Broadly, we discovered there is some emphasis on democratic values and some on technological innovation. We also found varying levels of knowledge on this topic in Mexican municipalities. Another finding is that OG policies are not well-defined due to a lack of resources for the promotion of genuine transparency, participation, and collaborative actions.
Rifampicin Suppresses Amyloid-β Accumulation Through Enhancing Autophagy in the Hippocampus of a Lipopolysaccharide-Induced Mouse Model of Cognitive Decline
Authors: Zhu Lihong , Yuan Qiongru , Zeng Zhaohao , Zhou Ruiyi , Luo Rixin , Zhang Jiawei , Tsang Chi Kwan , Bi Wei
Published: December 2020

Background:

Alzheimer’s disease (AD) is characterized by amyloid-β (Aβ) deposition. The metabolism of Aβ is critically affected by autophagy. Although rifampicin is known to mediate neuroinflammation, the underlying mechanism by which rifampicin regulates the cognitive sequelae remains unknown.

Objective:

Based on our previous findings that rifampicin possesses neuroprotective effects on improving cognitive function after neuroinflammation, we aimed to examine in this study whether rifampicin can inhibit Aβ accumulation by enhancing autophagy in a mouse model of lipopolysaccharide (LPS)-induced cognitive impairment.

Methods:

Adult C57BL/6 mice were intraperitoneally injected with rifampicin, chloroquine, and/or LPS every day for 7 days. Pathological and biochemical assays and behavioral tests were performed to determine the therapeutic effect and mechanism of rifampicin on the hippocampus of LPS-induced mice.

Results:

We found that rifampicin ameliorated cognitive impairments in the LPS-induced mice. In addition, rifampicin attenuated the inhibition of autophagosome formation, suppressed the accumulation of Aβ1–42, and protected the hippocampal neurons against LPS-induced damage. Our results further demonstrated that rifampicin improved the neurological function by promoting autophagy through the inhibition of Akt/mTOR/p70S6K signaling pathway in the hippocampus of LPS-induced mice.

Conclusion:

Rifampicin ameliorates cognitive impairment by suppression of Aβ1–42 accumulation through inhibition of Akt/mTOR/p70S6K signaling and enhancement of autophagy in the hippocampus of LPS-induced mice.
Analysis of a model for longitudinal electromagnetic stirring in the continuous casting of steel
Authors: Nick Arash S. , Vynnycky Michael , Jönsson Pär G.
Published: December 2020

A recent three-dimensional (3D) model that revisited earlier theoretical work for longitudinal electromagnetic stirring in the continuous casting of steel blooms is analyzed further to explore how the bloom width interacts with the pole pitch of the stirrer to affect the magnetic flux density. Whereas the first work indicated the presence of a boundary layer in the steel near the interface with the stirrer, with all three components of the magnetic flux density vector being coupled to each other, in the analysis presented here we find that the component along the direction of the travelling wave decouples from those in the other two directions and can even be determined analytically in the form of a series solution. Moreover, it is found that the remaining two components can be found via a two-dimensional computation, but that it is not possible in general to determine these components without taking into account the surrounding air. The validity of the asymptotically reduced model solution is confirmed by comparing it with the results of 3D numerical computations. Moreover, the asymptotic approach provides a way to compute the time-averaged Lorentz force components that requires two orders of magnitude less computational time than the fully 3D approach.
A binary choice model with partial observability for panel data
Authors: Batalova Ekaterina , Furmanov Kirill , Shelkova Ekaterina
Published: December 2020

We consider a panel model with a binary response variable that is a product of two unobservable factors, each determined by a separate binary choice equation. One of these factors is assumed to be time-invariant and may be interpreted as a latent class indicator. A simulation study shows that maximum likelihood estimates from even the shortest panel are much more reliable than those obtained from a cross-section. As an illustrative example, the model is applied to Russian Longitudinal Monitoring Survey data to estimate a proportion of the non-employed population who are participating in job search.
Regular uniform main-effect designs derivable from geometric factorial designs in 2n runs
Authors: Boguslavsky Ilya , Z. Brodsky Slava , R. Ioffe Gena
Published: December 2020

The article introduces a general method of construction of asymmetrical regular factorial main-effect designs in 2n runs. It presents a collection of optimal designs constructed by this method in 32, 64, 128, and 256 runs. The method provides exploration of design structure and construction of designs with required properties. Construction of composite designs is given as an example of design structure exploration.
Discussing copulas with Sergey Aivazian: A memoir
Authors: Fantazzini Dean
Published: December 2020

Sergey Aivazian was the head of my department at the Moscow School of Economics, but he was much more than that. He played an important role in my life, and he contributed to my studies devoted to copula modelling. This small memoir reports how this amazingly polite and smart scientist helped me to develop my academic skills and to further stimulate my interest in multivariate modelling and risk management. Some open questions related to multivariate discrete models that were among the last topics I discussed with Sergey are reported, hoping they can be of interest to young researchers for further studies.
The functional assessment for control of trunk (FACT): An assessment tool for trunk function in stroke patients
Authors: Sato Keisuke , Maeda Keisuke , Ogawa Takahiro , Shimizu Akio , Nagami Shinsuke , Nagano Ayano , Murotani Kenta , Inoue Tatsuro , Suenaga Masaki
Published: December 2020

BACKGROUND: The Functional Assessment for Control of Trunk (FACT) was developed to evaluate trunk function after stroke. However, only a few studies used FACT to show functional outcome. OBJECTIVE: This study aimed to validate the FACT predictive ability for functional outcome following stroke and create an English version of the FACT. METHODS: This retrospective, observational study was conducted with patients aged≥65 years with stroke. Patients were divided into two groups according to the median FACT score at admission: trunk impairment or high trunk function group. Multiple regression analysis was performed for Functional Independence Measure (FIM) gain and FIM efficiency to examine the relationship between trunk function assessed by FACT at admission and functional prognosis. RESULTS: 105 participants (mean age, 80.2±7.6, 57.1%were men) were included. Of these, 48 (45.7%) and 57 (54.3%) were categorized to the trunk impairment group and high trunk function group, respectively. FACT score at admission was associated with FIM gain (coefficient = 0.875, P = 0.001) and FIM efficiency (coefficient = 0.015, P = 0.016) after adjusting for confounders. CONCLUSIONS: Trunk impairment at admission assessed by FACT could predict functional prognosis. The English version of FACT was created and further demonstrated the validity of FACT.
Official statistics, big data and civil society. Introducing the approach of “economics of convention” for understanding the rise of new data worlds and their implications
Authors: Diaz-Bone Rainer , Horvath Kenneth
Published: December 2020

The rise of big data and ongoing political and social transformations confront official statistics with important questions regarding its self-understanding and its role in public debates. These questions imply serious tensions that will very likely increase in the foreseeable future. This article introduces a specific sociological perspective for thinking and talking about these developments. Building on the “economics of convention”, this perspective challenges currently dominant conceptions of official statistics which do not adequately mirror the plurality of possible representations of the social world and the variety of justifiable ways of assessing the quality of these representations. Taking these pluralities into account allows to develop a fuller picture of the actual practices and institutions involved in the production of statistical knowledge and, especially, of their unavoidable entanglement with normative orders, epistemic values, and political formations. The notion of “data worlds” is presented as a means for tackling this problem of pluralities. On this conceptual basis, it becomes possible to link methodological questions to analyses of how statistical data and knowledge are embedded in wider political, economic, and social contexts. Problems of “data quality” thus appear in a different light: their reflection involves more than the usually discussed issues of the institutional independence (secured by public funding and by law) and the high scientific standards of official statistics. Instead, an institutionalist theoretical approach is needed that offers blueprints for linking the production of “official statistical facts” to (always contested and contextual) conceptions of the common good. Such a conception would allow to conceive new forms of public participation and democratic control of processes of quantification, measurement, and datafication. In sum, we believe that the specifically sociological approach outlined in this article would support official statistics in dealing with the variety of critical interventions and challenges it currently faces in a proactive and coherent manner.
Meniere’s attack – a volume or pressure phenomenon?
Authors: Djennaoui Idir , Avan Paul
Published: December 2020

Meniere’s disease (MD) still raises since its discovery in 1860 pathophysiological and etiopathogenical issues. The main pathophysiological feature that has emerged for decades is an anatomic one, the endolymphatic hydrops (EH), defined by the inflation of the endolymphatic part of the membranous labyrinth. However, the causal relationship between EH and MD has not been proven. Several attempts have been achieved in animals to induce EH. The best known is the blockage of the vestibular duct, which causes a chronic volume inflation of the endolymphatic part. This model is characterized by the discrepancy between electrophysiological findings and scala media inflation. Pressure measurements vary among studies. The endolymphatic infusion model, which attempts to model the acute clinical picture of MD consistently shows pressure equilibration between the endolymphatic and perilymphatic compartments, and rapid recovery of the electrophysiological finding once the injection is stopped.
MANAJEMEN SEKOLAH MUSLIM MINORITAS: Menguji Kontribusi Kepemimpinan Kepala Sekolah pada Kinerja Guru di Papua Barat
Authors: Yudiawan Agus , Putri Faradillah Wirjaza
Published: December 2020

Educational governance in schools is closely related to the concept of leadership and the quality of teacher work. Of course, a good leader must be able to understand and carry out various leadership functions in moving his teacher. So that the goals of the educational institutions he leads can be realized immediately. This study aims to examine the principal's leadership function and its contribution to teacher performance in minority Muslim schools. This study used a quantitative descriptive approach with a population of 30 teachers. The entire population was sampled using the saturated sampling technique. Data were collected by distributing questionnaires and analyzed descriptively and inferentially. The inferential analysis used a simple linear regression model. The results showed that: principals were able to carry out leadership functions well (76,7%), teacher performance is in the medium category (59,8%), and principal leadership contributes positively and significantly to teacher performance in Muslim minority areas. It can be concluded that, if the leadership functions are carried out properly, the teacher's performance will increase.
Analisis Sifat Mekanik Karet Silikon sebagai Kandidat Prepusium Sintetik pada Alat Peraga Khitan
Authors: Khafidh Muhammad , Firdaus Abdullah , Velayati Ilham Akbar
Published: December 2020

Khitan atau sunat (sirkumsisi) merupakan proses tindakan medis berupa pembuangan sebagian dari kulit luar penis (prepusium) yang membungkus kepala penis (glans). Di Indonesia, khitan banyak dilakukan pada anak laki-laki ketika mencapai masa usia 7 sampai 12 tahun. Tindakan khitan dapat dilakukan oleh berbagai profesi tenaga kesehatan, seperti dokter, perawat, dan mantri sunat. Untuk melatih keterampilan tindakan khitan, salah satu metode yang dapat digunakan adalah dengan menggunakan alat peraga khitan sebagai sarana latihan memotong dan menjahit kulit penis. Tetapi, alat peraga khitan masih minim ditemukan di Indonesia. Salah satu poin penting dari alat peraga khitan adalah adanya kulit sintetis yang sifat mekaniknya mirip kulit asli agar ketika latihan memotong dan menjahit mempunyai feeling yang sama. Penelitian ini bertujuan untuk membuat dan menganalisis sifat mekanik karet jenis silikon sebagai material pengganti prepusium pada alat peraga khitan. Pengujian sifat mekanik dari prepusium dan karet silikon menggunakan Dynamic Mechanical Analyzer (DMA). Hasil penelitian menunjukkan modulus elastisitas prepusium dan silikon mempunyai tren yang sama, tetapi mempunyai nilai eksak yang berbeda. Berdasarkan hasil survei yang dilakukan terhadap beberapa praktisi khitan di Yogyakarta, kulit sintetis mudah dipotong dan dijahit serta mempunyai feeling yang mendekati sebenarnya.
The Effect of School Principal’s Servant Leadership of Vocational Schools in Temanggung Regency
Authors: Pratomo Bagas Dwi , Arifin Zainal
Published: December 2020

This research aims to examine the effect off school principal's servant leadership, discipline, work motivation, and teacher’s commitment on the performance of vocational school teachers in Temanggung Regency. The findings show that (1) servant leadership has no significant positive effect on performance; (2) servant leadership has a significant positive effect on discipline by 25%, 18% on work motivation, and 20% on commitment; (3) discipline, work motivation, and commitment significantly have positive effect on performance by 71%; and (4) servant leadership has a significant positive effect on performance through discipline, work motivation, and commitment. Significant performance improvement is not influenced by servant leadership. However, servant leadership has a significant positive effect through mediation of discipline, work motivation, and commitment.
Analysis of North Sulawesi’s Beef Cattle Farming Empowerment Strategy with Websites
Authors: Rembang Very L.H , Tumewu Judy M. , Lainawa Jolyanis
Published: December 2020

The production of beef cattle farming enterprises in North Sulawesi has not been able to meet people consumption needs. This condition is due to their slow absorption of breeding technology information among farmers, while the existing internet technology is merely used for entertainment needs. This research paper is to encourage the formation of an empowering model for beef cattle farmers in rural areas using websites. The findings suggested that the design model should be based upon farmer’s capabilities and existence of farmers, since they have adequate information about websites as outreach media needed for farmer empowerment.
Design and Simulation of RC Pipe Inspection Robot
Authors: Ganesh Padamala , Basha U. Mahaboob , Subramanyam L. Bala , Niak S. Jithendra
Published: December 2020

In recent days, most of the industries are facing many problems to find out damages inside the pipe line. The pipe inspection Robot was made to avoid this problem and to find out the exact place of damage and to reduce the time of evaluating, repairing and managing of interior surface pipes. One of the most important requirements in inspection, repairing and maintenance of interior pipelines is the ability to monitor and evaluate interior surface of pipes. This research work deals with the modelling of robot for inspection, cleaning, maintenance to evaluate the interior surface piping systems. The design of pipe inspection robot has been done in NX Cad (UNIGRAPHICS).the robot is designed in such way that it can be used for different pipe diameters. The design and development of pipe inspection robot involves a mechanism which in turn is connected to two opposite sides of frame of links, joints and wheels. So by using this pipe inspection robot one can find out the exact location of damage inside the pipe, so that it will be very easy to resolve the problem.
Proposta de implementação de plataforma E-commerce: Estudo de caso na Empresa Hayana Comercio de Calçados e Materiais Esportivos LTDA
Authors: Duarte Marcelo Henrique Barros , Santos Filho Leonardo Mendes , Lamego Thiago Pantoja , Roberto José Carlos Alves
Published: December 2020

O chamado E-commerce tem evoluído aceleradamente desde o início dos anos 2000 no Brasil. Por isso, desde lá tem sido assunto constante em reportagens sobre oportunidades de negócios divulgadas por jornais, revistas e veículos que tratam do assunto, como um dos meios mais eficientes para a administração de produtos, venda e alcance de clientes de lojas criadas na internet. Com o fácil acesso à internet nos dias atuais, as empresas e indústrias estão migrando cada vez mais para o mercado virtual, a estes exemplos podemos citar a loja Bemol, Ramsons dentre outras lojas de eletrodomésticos, livrarias, etc. As plataformas digitais a partir disso tornaram-se ferramentas importantes e eficazes na venda de produtos. O artigo em questão visa apresentar a eficácia das estratégias que as plataformas virtuais apresentam para administrar uma empresa de calçados no mercado online, a Hayana Comércio de Calçados e Materiais Esportivos LTDA, analisando as diferentes plataformas e seus benefícios ao empreendedor. Para tanto fora realizada uma pesquisa exploratória, de caráter qualitativo e posteriormente, buscou-se dentre estas plataformas a mais utilizada nos últimos anos, para então realizar o desenvolvimento do trabalho. Os benefícios de uma loja virtual são amplos, variando de acordo com a loja virtual escolhida, sendo assim, o empresário precisa estar sempre alerta aos indicadores de sua empresa, assim mantendo seus negócios atualizados e buscando desenvolver cada vez mais sua empresa para se manter no mercado com as grandes empresas virtuais, por essa razão uma análise de plataformas torna-se necessária.
Policy measures for electric vehicle adoption. A review of evidence from Norway and China
Authors: Hasan Saiful , Andreas Mathisen Terje
Published: December 2020

Purpose To mitigate energy and environmental challenges, several countries worldwide are considering different policies to promote the use of electric vehicles (EVs). Consequently, the necessity of studies focusing on the important and effective EV policy measures are develop-ing as policymakers are seeking to prioritize the policy measures based on their usefulness to achieve mass EV adoption. This study reviews evidence from China and Norway to identify factors that could substantially accelerate demand for EVs. Method We emphasize the cases of Norway and China, as these countries have already initiat-ed incentive-strong policies to accelerate EV's acceptance in their market and have succeeded considerably in improving their EV market share during the early adoption phases. The find-ings and discussion of this study is principally based on the reviewed literature of related poli-cy measures and two cases of successful EV uptake policies, Findings The evidence points at the significance of EV policy measures such as purchase-based and use-based incentives, availability of publicly accessible charging infrastructures, availability of EVs in the local market and collective communication measures. As findings, we have developed a general framework of essential EV policy measures. The reviewed litera-ture and cases suggest that publicly accessible charging infrastructures and financial incentives play crucial role in uptake. Conclusion Our study suggests that to accelerate EV penetration in the market, it is required the policymakers to pay more attention to the policy measures included in our general frame-work. However, the magnitude of the influences and interplay between these policy measures may differ between regions and on the context. Hence, policymakers should reconsider and restructure the EV polices after a certain level of EV-uptake is realized in the market.
How upright a public bus transport system is desirable for sustainable mobility?
Authors: Jain Pragati , Jain Prerna , Kaushik Roopesh
Published: December 2020

Sustainable mobility demands the inclusion of environment, social and economic sustainabil-ity. Public transport especially the bus system can be explored to fulfill these three sub goals. Globally the uses of personal vehicles have noticed an exponential growth owing to high per capita income and not up to the mark standards of public transport system. The emphasis on the requirement to probe significant questions while designing urban transport policies moti-vates this study to investigate what an ideal public bus system should be like, in the eyes of, those who either do not use or have shifted from public to private mode of travel. A survey on 1554 respondents is conducted to identify the various attributes that the public desire for, of a public bus system. These 12 items or attributes are clubbed into four categories using factor analysis. The logit regression run on the binary outcome "Shift" variable of opting or not opt-ing for public bus system with the four predicator variables (institutional, personnel, personal and qualitative) obtained using factor analysis shows positive association of improvement in these predicators to the outcome of opting for public transport.
Asymmetric impact of oil price shocks on selected macroeconomic variables: NARDL exposition
Authors: Philip Chimobi Omoke , Emmanuel Uche
Published: December 2020

The preoccupation of this study is to give empirical explanations to the existing relationship between oil price dynamics and some selected macroeconomic variables in Nigeria. Specifical-ly, it seeks to identify if the impacts of the changing oil prices on output, investment and un-employment is symmetric or asymmetric. Monthly time series data used in the research was subjected to a nonlinear analysis through the newly developed NARDL. To that effect, our findings reveal that changes in oil prices has asymmetric effects on the chosen macroeconomic variables. Our findings call for different policy formulations for up and down swings in oil prices
Capacità informativa della disclosure volontaria sulle risorse intangibili: effetti sul mercato finanziario italiano
Authors: Rizza Carmela , Greco Angela M. , Rizzotti Davide
Published: December 2020

Gli studiosi delle discipline aziendali si sono occupati degli effetti che la

volontaria delle informazioni sulle risorse intangibili ha sulle valutazioni degli investitori, prescindendo dalle peculiarità del contesto italiano e dalle differenti configurazioni del processo di

. Questo lavoro, attraverso un'indagine empirica svolta analizzando le informazioni relative alle società quotate nella Borsa italiana nel periodo 1998-2008, verifica il peso che il mercato finanziario italiano assegna alla

volontaria di informazioni sulle risorse intangibili e alle differenti configurazioni con cui essa si può svolgere. I risultati ottenuti mettono in evidenza come tale sensibilità sia influenzata, in particolare, dallo strumento di comunicazione adottato.
La disclosure dei resoconti semestrali di gestione IAS-compliant. Evidenze empiriche sulle società quotate italiane
Authors: Lucchese Manuela
Published: December 2020

Nel presente lavoro ci si propone di analizzare empiricamente il livello di disclosure integrativa presentata nei bilanci infrannuali conformi allo IAS 34. In particolare, si cerca di capire in primis se, data la crescente complessità aziendale, sia riscontrabile un incremento del grado di dettaglio delle informazioni integrative pur nel rispetto dei requisiti minimi indicati dallo standard. Successivamente, si provvede a verificare se il diverso livello della disclosure rappresentata sia imputabile a talune caratteristiche specifiche delle imprese quali la dimensione aziendale, la redditività, la struttura finanziaria, il rischio di mercato ed il rischio d'impresa. Il campione utilizzato per l'indagine empirica include i bilanci semestrali di 64 imprese italiane quotate pubblicati nel periodo 2005-2009. I principali risultati dimostrano che a livello infrannuale non si rileva un significativo incremento del grado di dettaglio informativo e che variabili come un'ampia dimensione nonché una più elevata redditività giocano un ruolo determinante nelle politiche di disclosure.
Rilevanza ed affidabilità del valore contabile dell'avviamento e dei beni immateriali sul mercato italiano
Authors: Liberatore Giovanni , Ridi Tommaso , Di Pietro Filippo
Published: December 2020

Il presente lavoro si propone di indagare quale sia la rilevanza e l'affidabilità percepita dal mercato finanziario sul valore espresso nel bilancio d'esercizio sui beni immateriali e l'avviamento delle società quotate. Lo studio ha analizzato le aziende quotate al FTSE Italia All-share, nel periodo fra il 2002 ed il 2008. Attraverso un modello di regressione a più variabili si è verificato che: a) il valore contabile dei beni immateriali e dell'avviamento sono correlati positivamente al valore di mercato del capitale, b) la transizione agli IAS/IFRS non ha comportato un incremento della rilevanza ed affidabilità percepita dal mercato dei beni immateriali e avviamento.
Paura, ansia, angoscia, panico nelle concettualizzazioni psicoanalitiche
Authors: Bolognini Stefano
Published: December 2020

L'autore traccia una classificazione concettuale psicoanalitica delle varie condizioni psichiche di allarme, indicando una sequenza progres-siva basata sui differenti livelli qualitativi e di intensità dell'esperienze funzionali che ne derivano. La descrizione si articola in un continuum che va dalla normale e necessaria paura al panico, passando dai livelli intermedi costituiti dall'ansia fisiologica, all'ansia patologica e dall'angoscia. L'autore mette in rilievo come le concettualizzazioni su queste condizioni psichiche e la loro classificazione in psicoanalisi non siano definitive ed espone il suo pensiero definendolo realistico e deri-vante dall'esperienza clinica. Sono descritte diverse concettualizzazioni psicoanalitiche, a partire dal pensiero di Freud. Nella conclusione del lavoro egli mette in evidenza il percorso del vissuto del paziente duran-te il trattamento terapeutico: dall'iniziale sentimento sperimentato di crollo dell'Io, caratterizzato dalla mancanza di fiducia in se stesso fin verso la fine del percorso analitico in cui il paziente può pensare di "cominciare" a fidarsi di sé.
Interpretazione dell'emergenza. Riflessioni cliniche
Authors: Biggio Gianluca
Published: December 2020

L'autore espone alcune considerazioni sull'influenza che l'emergenza Covid-19 ha riverberato nel mondo interno dei pazienti e della terapia stessa. Prende in considerazione la fase iniziale, Fase 1, in cui il lockdown ha modificato l'assetto terapeutico. Nella successiva Fase 2, con la riapertura parziale della socialità, si pongono nuovi pro-blemi riguardo alle fantasie collettive e a quelle dei pazienti, relativa-mente a un "ritorno alla normalità" che appare più oneroso e meno semplice di quanto si era fantasticato. Vengono riportati il sogno di un paziente che si sta avvicinando alla conclusione della terapia durante il lockdown; il sogno pur in una seduta a distanza fa scaturire una sorta di intimità onirica condivisa tra paziente e analista. Tale intimità si riper-cuote in una rêverie dell'analista al risveglio a ridosso della seduta. Successivamente viene riportato un flash clinico di una paziente che riprende le sedute in presenza nella Fase 2, ripresa che si rivela più complessa del previsto nella gestione di un'attesa riparativa tra un sen-timento di timore e di speranza al tempo stesso.
Movimenti del setting e delle emozioni nella relazione analitica ai tempi della pandemia
Authors: Maugeri Adelina
Published: December 2020

In questo lavoro l'autrice offre una riflessione sulla esperienza traumatica vissuta durante l'emergenza per la pandemia Covid-19, esaminandola attraverso richiami teorici riguardanti i fenomeni della relazione corpo-mente, del funzionamento dei gruppi e attraverso l'esperienza della comunità psicoanalitica. Fa riferimento alla esperien-za di un gruppo di studio di analisti e a due flash clinici, in una dimen-sione in cui il distanziamento sociale, che si è imposto alla modalità di relazione in presenza di altri, ha richiesto l'appoggio a strumenti mul-timediali, andando a modificare l'assetto dei setting. Una dimensione in cui le senso-percezioni ridefiniscono la percezione di sé e di sé nella relazione con l'altro. Un trauma collettivo che propone piani di simme-tria nella relazione analista-paziente in quanto entrambi vittime della stessa minaccia alla vita.
"Urtati nel buio"
Authors: Algini Maria Luisa
Published: December 2020

Il lavoro sviluppa l'idea che quanto stiamo sperimentando nel tem-po del Covid e ci ha messi in crisi come persone e come analisti, ci co-stringa ad aprire nuovi sguardi sulla clinica e sulla teoria, e ad approfondire il senso della relazione analitica e degli strumenti che usiamo. Le dinamiche imposte dalla pandemia hanno fatto intuire che la qualità del lavoro psicoanalitico si amplia, si rafforza, prende nuovo senso, se siamo capaci di non rimuovere il sentimento di precarietà sperimentato, facendo nostra l'idea che le svolte creative nella storia della psicoanali-si sono nate proprio da tempi drammatici.
Emergenze interne ed emergenze esterne: il caso di Dorian
Authors: Perrotta Luigi Antonio
Published: December 2020

L'emergenza ha richiesto risposte a condizioni inedite e impreviste. I cambiamenti che hanno travolto la coppia analitica sono stati diversi, hanno attivato dinamiche psichiche complesse, mobilitato fantasmatiche peculiari e sollecitato aspetti psicopatologici specifici di ciascun paziente. Dal timore del cambiamento di setting, alla speranza di man-tenimento di un legame, ancora più fondamentale in un momento criti-co simile, la priorità è stata preservare uno spazio di contenimento e di lavoro di angosce primitive esponenzialmente cresciute e condivise in maniera simmetrica anche con l'analista. Il contributo, attraverso una situazione clinica emblematica, descrive l'irrompere di aspetti esterni, legati all'emergenza, e di come essi abbiamo mobilitato aspetti interni del paziente, incidendo sul processo terapeutico già in corso.
Popolazione transgender over 50: un intervento clinico psicosessuologico
Authors: Girardi Marta , Fabrizi Adele , Simonelli Chiara
Published: December 2020

Il concetto di identità di genere è stato motivo di interesse e di studio negli anni fino a giungere alla sua concezione transgender, caratterizzata da un lungo percorso di depatologizzazione che parte dai primi studi di differenziazione tra sesso e genere fino ad arrivare alle classificazioni che i vari manuali diagnostici oggi ci presentano. La concezione transgender dei generi supera la concezione binaria, proponendo una visione fluida che legittima l'esistenza di una varietà di identità di genere in cui potersi riconoscere. I bisogni relativi all'invecchiamento e alla salute degli anziani LGBT sono scarsamente affrontati nei servizi, nelle politiche o nella ricerca. La popolazione transgender over 50, la quale ha vissuto in un contesto so-ciale e storico caratterizzato da forti discriminazioni, si trova ad affrontare una fase di transizione della vita in cui è importante considerare le caratteristiche peculiari di tale vissuto come transgender e gli aspetti relativi alla salute fisica e al supporto sociale. Affacciarci alla visione di invecchiamento transgender vuol dire adottare una prospettiva che si distanzia dagli script eteronormativi prevalenti nella società, e che si avvale di concezioni tipiche di tale vissuto, come quella di queer time e queer space. L'obiettivo di tale contributo è quello di evidenziare le problematiche e le esigenze della popolazione considerata per poter promuovere una figura di clinico attento e consapevole delle peculiarità dell'utenza considerata e un intervento clinico psicosessuologico ad hoc che adotti un approccio biopsicosociale.
Curare l'uomo, non il sintomo: la promozione della salute sessuale nella sclerosi multipla secondo l'approccio integrato
Authors: Dasara Eloisa , Todaro Elisabetta
Published: December 2020

La sclerosi multipla è una patologia autoimmune cronica e degenerativa, ad eziologia sconosciuta, che colpisce il sistema nervoso centrale. Da un'indagine AISM-CENSIS del 2017 emerge come circa il 50% delle persone affette da tale patologia lamentino sofferenza significativa nell'area di funzio-namento psicologico; tale dato viene ipotizzato strettamente correlato al tema del-la graduale diminuzione dell'autosufficienza percepita. Tale dimensione diviene ancora più presente qualora il soggetto si trovi in una relazione di coppia, la quale passa dall'essere simmetrica e paritaria all'essere caratterizzata da una iniqua di-stribuzione del senso di autonomia e autosufficienza. Stando a quanto diffusamente affermato dalla Dichiarazione dei Diritti Sessuali, dai documenti tecnici e dalla letteratura scientifica internazionale, la salute sessuale è fondamentale nella definizione del benessere individuale e relazionale. Di conseguenza, anche quando un soggetto si trovi in una condizione di patologia cronica ingravescente, è necessario non solo indagare l'eventuale presenza di disa-gi nella sfera sessuale, ma anche utilizzare strumenti di intervento integrato per po-terli affrontare adeguatamente. Dall'analisi della letteratura considerata emerge come, nonostante la mole di studi prodotti in direzione di una gestione integrata tra diverse competenze clini-che, emergano numerose difficoltà nell'armonizzare i diversi interventi in un mo-dello di cura integrato. Si ipotizza che tale scenario sia conseguenza della profonda scissione esistente, ancora oggi, nella presa in carico dei pazienti con patologia cronica, considerati "corpo" o "psiche", con una conseguente impossibilità di prendersi cura dell'uomo nella sua complessità.
Електронне судочинство: міжнародний досвід
Authors: Голубєва Неллі
Published: December 2020

У монографії викладаються актуальні проблеми та питання впровадження досягнень науково-технічного прогресу, комп'ютерної техніки та інформаційних технологій у цивільне судочинство зарубіжних країн та України. Електронне судочинство виступає не тільки як інструмент організації судочинства для підвищення його ефективності, але й як спосіб полегшення доступу до правосуддя, а в ідеалі – новий спосіб відправлення правосуддя. В роботі визначено напрями подальших наукових досліджень, пошуку нових законодавчих рішень, теоретичних формулювань. Монографія призначена для науковців, юристів-практиків, аспірантів, студентів юридичних вузів і факультетів, а також для всіх, хто цікавиться даною тематикою.
Meningkatkan Aktivitas dan Hasil Belajar Siswa Melalui Model Pembelajaran Kooperatif Tipe Two Stay Two Stray pada Mata Pelajaran Ekonomi Kelas XI IPS 2 di SMA Negeri 1 Tapa
Authors: Puspita Miranda , Hinelo Ismail Raflin , Bahsoan Agil
Published: December 2020

Tujuan penelitian ini adalah untuk meningkatkan aktivitas dan hasil belajar siswa pada mata pelajaran Ekonomi kelas XI IPS 2 di SMA Negeri 1 Tapa melalui model pembelajaran kooperatif tipe two stay two stray. Metode penelitian yang digunakan adalah metode penelitian tindakan kelas. Sampel penelitian adalah siswa kelas XI IPS 2 yang berjumlah 32 siswa. Teknik pengumpulan data adalah wawancara, observasi, tes aktivitas belajar, tes hasil belajar, dan dokumentasi. Penelitian dilaksanakan dengan 2 siklus. Teknik analisis data digunakan kuantitatif deskriptif. Kesimpulan dari penelitian ini adalah terdapat peningkatan aktivitas dan hasil belajar siswa pada mata pelajaran Ekonomi kelas XI IPS 2 di SMA Negeri 1 Tapa dibuktikan dari meningkatnya jumlah siswa yang aktif pada observasi awal 8 siswa (25%) menjadi 23 siswa (72%) pada siklus I, kemudian meningkat menjadi 28 siswa (88%) pada siklus II. Jumlah siswa yang memperoleh nilai ≥ 75 pada observasi awal 9 siswa (28%) menjadi 24 siswa (75%) pada siklus I, kemudian meningkat menjadi 28 siswa (88%) pada siklus II. Dengan demikian, hipotesis penelitian yang berbunyi “Jika guru menggunakan model pembelajaran kooperatif tipe two stay two stray, maka aktivitas dan hasil belajar siswa pada mata pelajaran Ekonomi kelas XI IPS 2 di SMA Negeri 1 akan meningkat” dapat diterima karena terbukti kebenarannya.
Palladium (II) chloride (PdCl2) spectrophotometry to determine lipoic acid concentration in plasma and leukocytes
Authors: Yudhaswara Novian Agni , Prijanti Ani Retno , Sadikin Mohamad
Published: December 2020

Background: Lipoic acid is a substance contained in intra and extracellular that act as a coenzyme of Pyruvate Dehydrogenase, also as an antidote, chelating agent and antioxidant. Measurement of lipoic acid is needed to determine the amount of lipoic acid that performs its functions either as a coenzyme or an antioxidant. Besides, this measurement requires a special tool such as High Performance Liquid Chromatography (HPLC) and a process that is available in rural or simple laboratories.  

Objective: A common and easy tool such as a spectrophotometer was conducted and could expected to be a tool of lipoic acid determination in body fluid such as plasma.

Methods: Measurement of lipoic acid using spectrophotometry with UV methanol and visible PdCl2 has been tested and compared to HPLC measurement that was valid and reliable in drug measurement or pharmaceutical preparations.

Results: Determination of lipoic acid in plasma and leukocytes using PdCl2 produced replicable, reliability and valid result, with high accuracy, precision and was not different from lipoic acid measurement using HPLC, p=0.99. While UV methanol was different compare to HPLC p =0.0001 or was not valid.

Conclusion: The measurement of lipoic acid using PdCl2 visible method can be applied to determine the levels of lipoic acid (LA) and DHLA in plasma and equal to HPLC result.
The effect of cyclophosphamide combined with zinc on male mice Mus musculus spermatozoa
Authors: Adhiwirawan Muhammad Fadzrul , Nugraha Yudhi , Fauziah Cut
Published: December 2020

Background: The usage of cyclophosphamide leads to infertility of reproductive system caused by acrolein. Acrolein can itself cause oxidative damage by depletion of cellular glutathione (GSH) by conjugation, leading to membrane disruption, DNA and mitochondrial damage and can exacerbate apoptosis, which may affect spermatogenesis. Zinc (Zn) which is constituents of superoxide dismutase, has a protective effect towards free radicals from physiological or pathologic effects to minimize the cell’s damage.  

Objective: The purpose of this research was to know the effect of Zn on the spermatozoa count of Mus musculus that was given cyclophosphamide intraperitoneally.

Methods: In the present study, cyclophosphamide was administered in saline 200 mg/kg 1x weekly for 5 weeks by ip route, whereas Zn was supplemented by oral route with doses of 25, 50, 100 mg/Kg/day for 5 weeks. The data were analyzed with Anova and followed by Bonferroni Test at a significant level of 5%.

Results: The result of this research revealed that high Zn diet and Cp administration decrease sperm count simultaneously. It showed by the decrease of sperm count from 1490 (1 x 103)/ml sperm in the control group becomes 240 (1 x 103)/ml sperm in treatment group with 100 mg/kg of oral Zn and 200 mg/kg of cyclophosphamide.

Conclusion: This research shows that Zn supplement to prevent cyclophosphamide toxic effect in spermatogenesis does not have a protective effect, in fact its reduce sperm count by excess of Methallothine production and alter the spermatogenesis by reduce Cu intake from intestine.