Influence of Drugs of Continuous Use on the Sensory Regulation of the Static Balance of Elderly Regular Practitioners of the Pilates Method
Authors: Nascimento Marcelo de Maio , De Deus Deborah Lays Silva , Rios Pâmala Morais Bagano , Silva Paloma Sthefane Teles 
Published: September 2021

AbstractThe combination of types of medications can compromise the regulation of body balance in older adults. This study evaluated the effect of continuous use drugs on the sensory regulation of static balance in elderly women who regularly practice the Pilates method with and without a history of falls and estimate the risk of falls in this population. Cross-sectional study, carried out with 94 women (67.12±4.74 years) practicing Pilates, divided into: non-fallers (n = 74) and fallers (n = 18). Sociodemographic data, comorbidities, medications, and Mini Mental State Examination (MMSE), Falls Efficacy Scale (FES), Confidence in Balance Scale (ABC) were applied. The examination of static balance was performed by the Clinical Test of Sensory Interaction and Balance (CTSIB). The risk of falling was analyzed using an adjusted multiple logistic regression model, while the effect of drugs on falls was estimated by binary regression, results were presented using the odds ratio (OR). The CTSIB test revealed Condition 4 (OR = 3.038; 95% CI = 1.321–15.674) and Condition 5 (OR = 5.542; 95% CI = 1.678–18.303) as predictors of falls. Drugs showing an effect on fall were β2 agonist associated with glucocorticoid (OR = 0.245; 95% CI = 1,233–2,400), thiazide diuretic (OR = 0.344; 95% CI = 1.122–2.234), statin (OR = 0.245; 95 % CI = 1,237–2,338), angiotensin II receptor antagonist (OR = 0,245; 95% CI = 1,236–2,339), beta blocker (OR = 0,245; 95% CI = 1,238–2,402) and anti-vertigo (OR = 0,245; 95 % CI = 1.230–2.399). Regardless of the history of falls, the risk of falling was present in older adult regular Pilates practitioners. Six different drugs for continuous use showed an effect on falls.Keyword: Accidental Falls. Aging. Women´s Health. Accident Consequences.ResumoA combinação de tipos de medicamentos pode comprometer a regulação do equilíbrio corporal de idosos. Este estudo avaliou o efeito de fármacos de uso contínuo sobre a regulação sensorial do equilíbrio estático de mulheres idosas praticantes regulares do método Pilates com e sem histórico de queda e estimar o risco de queda dessa população. Estudo transversal, realizado com 94 mulheres (67,12±4,74 anos) praticantes de Pilates, divididas em: não-caidoras (n=74) e caidoras (n=18). Foram coletados dados sociodemográfico, comorbidades, medicamentos, e aplicado Mini Exame do Estado Mental (MEEM), Falls Efficacy Scale (FES), Escala de Confiança no Equilíbrio (ABC). O exame do equilíbrio estático foi realizado pelo Clinical Test of Sensory Interaction and Balance (CTSIB). O risco de queda foi analisado pelo modelo de regressão logística múltipla ajustado, enquanto, que o efeito dos fármacos sobre queda foi estimado pela regressão binária, resultados foram apresentados pelo odds ratio (OR). O teste CTSIB revelou a Condição 4 (OR= 3,038; 95% IC= 1,321–15,674) e Condição 5 (OR= 5,542; 95% IC= 1,678–18,303) como previsora de quedas. As drogas que mostram efeito sobre queda foram agonista β2 associada com glicocorticóide (OR=0,245; 95% IC= 1,233–2,400), diurético tiazídico (OR=0,344; 95% IC=1,122–2,234), estatina (OR=0,245; 95% IC=1,237–2,338), antagonista do receptor de angiotensina II (OR=0,245; 95% IC=1,236–2,339), betabloqueador (OR=0,245; 95% IC=1,238–2,402) e antivertiginoso (OR=0,245; 95% IC=1,230–2,399). Independente do histórico de quedas, o risco de cair esteve presente em idosas praticantes regulares do Pilates. Seis diferentes medicamentos de uso contínuo mostraram efeito sobre queda. Palavras-chave: Acidentes por Quedas. Envelhecimento. Saúde da Mulher. Consequências de Acidentes.