bluuebunny/crossref_metadata_2025 huggingface dataset:
Loneliness and Culture: A Commentary
Authors: Ami Rokach
Published: May 2024

Loneliness is thean experience that is intertwined inwith being human, but since it is so painful and troubling, all of us try to avoid it. It has short- and long-term negative consequences, including its influence on our life satisfaction, health, and mortality. Various causal factors were explored regarding loneliness, which is essentially a subjective experience. This commentary aims to highlight the contribution of culture, be it collectivistic or individualistic, to the development of loneliness. Since loneliness is correlated with the expectation of being with others and part of a community, research found that people in collectivistic cultures are lonelier than those in individualistic ones. Ethnicity also contributes to the development, and was thus reviewed. While it beingis an essential part of being human, loneliness can, indeed, be attenuated and its pain lessened, and culture may predict ways of doing so.
Monkeypox Virus, A Global Public Health Concern and Challenge for Low-income Countries including Pakistan: A Right Time to Nip the Evil in the Bud
Authors: Zahra Zahid Piracha , Haider Ali , Noor ul Huda Rasheed , Umar Saeed , Syed Shayan Gilani , Umer Ali Abbasi , Qasim Khan , Elyeen Noor , Seneen Noor
Published: May 2024

Monkeypox is a rare zoonotic infection originating in the regions of Central and West Africa. The global threat has been arising since monkeypox is spreading outside of the endemic regions. Pakistan has recently exhausted health funds in a quarrel against SARS-CoV-2, by supplying expensive COVID-19 vaccines to the general public, free of cost. Pakistan’s government has remarkably contributed to lowering the suffering of COVID-19-affected patients by granting the Sehat Sahulat Programme and similar health initiatives to restrict viral propagation in the general public. However, despite all efforts the major constraints are a lack of international funds and limitations on the budget of healthcare systems and medical facilities. Newly emerged cases of monkeypox are very threatening to Pakistan’s economy and health. Therefore, it is very necessary that healthcare authorities take effective measures like surveillance, early identification, separation, monitoring of contacts, immunization, and public awareness in order to stop the spread of the virus and control monkeypox outbreaks.
Maternal, Snake-Tailed Foundress Melusine: A Transformative, Monstrously Transgressive Serpent Woman under the Gaze
Authors: Alban Gillian M. E.
Published: May 2024

Abstract: This article evaluates the fascination of the protean serpent woman or siren Melusine, demonstrating the illustrious heritage of this hybrid foundress of the Lusignan dynasty. Her supernatural achievements are celebrated through history, literature, and culture, despite her betrayal by her weaker husband. As feminine nymph or maternal foundress, Melusine and her achievements serve as exemplary for powerful women. She represents woman castigated as abject, monstrous, and possessed of a terrifying vagina dentata from the voyeuristic male perspective, whose usurping gaze destroys her authority. She yet remains revered and desired for her creative life force and the phallic or hermaphroditic power represented by her tail. Whether as snake-tailed woman in Eden or connected with fertility goddesses or the Virgin Mary, the protean Melusine emerges as a magnetic, sovereign figure in her self-sufficient sexuality. Her transgressive prowess as a theriomorphic, transformative woman breaks through boundaries and overturns debilitating assumptions regarding her sex, blazoning her unruly force. Castigated as Other while revered as divine, her story rises above any slighting gaze to amaze us with her stunning tale or tail, evoking admiration despite all attempts to diminish her.
Enslaved Women, Women Enslavers: Kyriarchy and Intersectionality in the New Testament
Authors: Cobb Christy
Published: May 2024

Abstract: Using a feminist hermeneutic, this essay analyzes three examples of kyriarchal relationships in the New Testament found in stories of women who were enslavers who enslaved women. The first example is from Galatians where Paul rereads the story of Sarah and Hagar and uses the enslaver/enslaved relationship as an allegory. The second example is found in Acts 12, which is the clearest case of a woman enslaver who enslaved a woman: Mary and Rhoda. Finally, I analyze the character of Lydia found in Acts 16 and argue that she is also an enslaver who enslaved women. Each of these biblical characters was entangled in the kyriarchal pyramid of antiquity through their own oppression due to gender, yet they participated in kyriarchy due to status and class. Adding evidence from material culture, I analyze an example of a woman who enslaved another woman as depicted on an ancient funerary monument. This essay also considers the ethical ramifications of biblical texts that endorse slavery and have been used to support white supremacy and systemic oppression.
Determining a Reliability Centered Maintenance (RCM) analysis model for large diameter prestressed concrete water pipelines
Authors: James Geisbush  , Samuel T. Ariaratnam
Published: May 2024

Which maintenance task to perform on an asset is generally known but the schedule of when to perform the task may not be well defined. If the task is performed early, while it may benefit the asset, it may also be expending resources that could be better used elsewhere. If the task is not performed soon enough, the asset may fail, or the asset may require more extensive maintenance be performed. Reliability Centered Maintenance (RCM) is an analysis process used to determine the most effective maintenance strategies. RCM analysis can help an agency establish the most cost effective maintenance strategies for an asset and help establish the best schedule for implementing those strategies. The ultimate goal of an RCM is to determine the required function of an asset with the required reliability at the lowest operation and maintenance costs by identifying revealing indicators of potential failures to establish a condition based strategy; essentially, predicting failures and identifying procedures to minimize the risk of the failure. This paper reviews potential models for predicting the progression of distress of prestressed concrete pipe segments for use in an RCM analysis and proposes a regression model operators can use to forecast when to perform maintenance activities. The paper further considers the condition of the drinking water infrastructure in the United States, developing the case for evaluating predictive models to forecast when a pipeline may reach a specified limit state. The results of this study suggest that RCM analyses for large diameter water pipelines can improve reliability, reduce maintenance costs, and extend the useful life of a pipeline regardless of age or material. Further, using a regression style model with gathered data can be used to forecast when specific maintenance thresholds may be reached, prompting predictive maintenance actions.
Comparative study on paddy harvesting technologies in Sylhet region
Authors: Shermin Aktar  , Warasa Mostafa  , Muhammad Rashed Al Mamun  , Khairul Islam
Published: May 2024

Mechanized paddy harvesting is currently limited in Bangladesh, but the pace of mechanization is increasing. Harvesting must be done on time to minimize losses and timely harvesting depends on the availability of harvesting machinery. The aim of this study was to find out the state of mechanized paddy harvesting technologies in Sylhet region over the last five years. The study was conducted in all upazilas under the Sylhet region to compare mechanized and manual paddy harvesting technologies. Structured questionnaire was used to collect data. The survey revealed the changes in mechanization status in 2022 compared to the previous four years. In the study area, the average paddy cultivable area was 0.91 million hectares. The pace of mechanized harvesting in Sylhet, Sunamganj, Habiganj, and Moulvibazar district were 31.49%, 24.41%, 19.59%, and 15.95%, respectively. On the basis of the provided data, from 2018 to 2022 the number of harvesting machines increased from 547 to 1852. The manual method, combine harvester, and reaper were used to harvest 76.20%, 21.90%, and 1.90% of the total projected area respectively in 2021-2022. The study revealed that combine harvester covered around 87.47% area than reaper. In 2022, among the 40 upazilas, the most machines were found at Nabiganj upazila in Habiganj district =106, and the fewest machines were found at Barlekha upazila in Moulvibazar district =10. The trend of manual paddy harvesting has declined in Sylhet region due to the increase in the number of harvesting machines. So, harvesting machineries are needed in this region to update paddy harvesting mechanization status.
Posterior reversible encephalopathy syndrome with functional and motor sequelae: A case report
Authors: Asma ELHANAFI  , Meriem BOURHERBAL  , Youness ABDELFETTAH
Published: May 2024

Posterior Reversible Encephalopathy Syndrome (PRES) is a rare clinicoradiological neurological disorder, initially elucidated in 1996, Since this first description of PRES numerous case reports and case series, as well as retrospective observational studies describing the syndrome have been published. Importantly, no randomized controlled studies have been performed, We present the case of a young patient with no significant medical history who presented with neurological symptoms consistent with Posterior Reversible Encephalopathy Syndrome (PRES). Brain MRI confirmed the diagnosis of Posterior Reversible Encephalopathy Syndrome (PRES). Additionally, the etiological assessment yielded negative results. A notable aspect in our patient's case is the persistence of sequelae, characterized by dexterity and grip impairment on the right side, hindering various activities of daily living. The diagnosis of PRES is both radiological and clinical, with MRI playing a crucial role. Treatment is primarily symptomatic, sometimes requiring intensive care unit admission. Prognosis is favorable in the majority of cases, but severe complications and even death can occur. The reversibility of initial symptoms is well-documented in the literature. Long-term functional impairment outcomes following PRES have not been adequately characterized in the literature. Therefore, it is necessary to conduct follow-up screenings in more patients presenting both typical and atypical PRES syndromes. This will provide insight into whether the functional and motor sequelae of PRES are less reversible.
A review on current scenarios of pharmaceutical and herbal medicine and future prospects
Authors: Mamata V. Surve  , Akshay S. Shyamsundar  , Ankita P. Jatale  , Swati P. Deshmukh
Published: May 2024

Plants are intentionally or unwittingly making a difference the living creatures since the starting of civilization. In spite of the fact that unused and modern maladies are getting found day by day, creator had given us with most of the remedy in the frame of restorative plants. Herbal medicate Industry is experiencing a major alter with regard to household and global necessities. Nutraceuticals is the quickest developing home-grown components due to increment in day to day way of life concern among worldwide populace. A number of logical examinations have highlighted the significance and the commitment of numerous plant families i.e. Asteraceae, Liliaceae, Apocynaceae, Solanaceae, Caesalpinaceae, Rutaceae, Piperaceae, Sapotaceae used as therapeutic plants. Therapeutic plants play a crucial part for the advancement of unused drugs. The bioactive extract ought to be standardized on the premise of dynamic compound. The bioactive extricate ought to undergo safety considers. Nearly, 70% advanced solutions in India are determined from characteristic items. Medicinal plants play a central part not as it were as conventional medications but too as exchange commodities, assembly the demand of far-off markets. India has a exceptionally little share (1.6%) of this evergrowing worldwide advertise. To compete with the developing advertise, there is direness to quickly utilize and deductively approve more medicinally valuable plantsIn 1991 WHO created rules for the appraisal of herbal pharmaceutical. Recommendations for home grown pharmaceutical standardization are out lined. The situation and recognition of home-grown medication are examined. The publicís conviction that home grown and normal items are more secure than manufactured solutions can as it were be discovered by forcing administrative benchmarks on these items that ought to be made utilizing these Great Hones. Home grown drugs are fundamental components of conventional pharmaceutical in several nations counting China and India. India has a well-established system of medication known as Ayurveda. Need of the Department of Biotechnology, Government of India and the Indian Chamber of Agricultural Inquire about, request that the beat 20 restorative plants in India be imported and traded from India vis-à-vis world request. Logical approval of phar- macological action of age-old drugs utilized in Ayurveda strengthens confidence in the traditional framework, in which plants are chosen as it were on the premise of encounter. Need of the Department of Biotechnology, Government of India and the Indian Board of Agricultural Inquire about, request that the beat 20 restorative plants in India be imported and traded from India vis-à-vis world request. Logical approval of pharmacological action of age-old drugs utilized in Ayurveda fortifies confidence in the traditional framework, in which plants are chosen as it were on the premise of encounter.
Comparison the effect of plant extracts and antibiotics on gram negative bacteria isolated from patients with urinary tract infection in Tikrit city
Authors: Sarwa Azeez Khaled
Published: May 2024

Background: With increasing bacterial resistance for antibiotic, there is an increasing interest in medicinal herbal as a new source of an antimicrobial agents and with less side effects than conventional drugs. Objective: Was to evaluate the potential of Syzygium aromaticum and rosemarinus officinalis extract on Proteus mirabilis isolates in vitro. Methods: Six pathogenic gram negative bacilli belonging to three different genus (E.coli, Proteus mirabilis, and Enterobacter aerogenes) and two isolates from each species were used in this study and four concentration (100%, 75%, 50%, 25% mg/ml ) from each plant extracts (aqueous and ethanolic of Syzygium aromaticum and rosemarinus officinalis extracts ) were prepared to be antibacterial agent. antibacterial activity was measured by using wells method and five antibiotics using to compare with the activity of antibacterial agent. Results: The result of the study shown that the ethanolic extracts of Syzygium aromaticum is a strong antibacterial agent (with diameter of inhibition zone 25 mm) against Proteus mirabilis. Enterobacter aerogenes with (15mm) of inhibition zon, E.coli did not show any inhibition zone also the aqueous and ethanolic of rosemarinus officinalis extracts and aqueous of Syzygium aromaticum extracts did not show any activity towards any gram negative bacilli also the results of the study show resistance isolates of E.coli and Proteus mirabilis toward several antibiotic while Enterobacter aerogenes is sensitive for more antibiotics that used in this study. Conclusions: Our study concluded that the extract of Syzygium aromaticum has high potential as antibacterial agent against UTI that caused by Proteus mirabilis, clove (syzygium aromaticum) can be used in pharmaceutical for the production of new synthetic agents. There is an increasing interest in phytochemicals as new sources of natural antioxidant and antimicrobial agents. The natural compounds which have biological activities are interest to pharmaceutical industries especially for treatment of human disease of microbial origin and several pathological disorders such as cancergenesis, coronary atherosclerosis, as well as in ageing processes.
Non-pharmacological interventions to prevent return of gastric ulcers: A systematic review
Authors: Mohammed Jamaleldeen Adam Ahmed  , Husnul Khotimah
Published: May 2024

Recurrence of gastric ulcers is a significant concern, and non-pharmacological interventions play an important role in their prevention. This systematic review aims to evaluate the effectiveness of nonpharmacological interventions in preventing gastric ulcer recurrence. The aim of this research is Non-Pharmacological Interventions to Prevent Recurrence of Gastric Ulcers: A Systematic Review". The research method in this study was the literature method. The literature method was carried out by means of a comprehensive search carried out in several databases, including PubMed, Medline, Scopus, and the Cochrane Library, using predefined search terms. Studies published from (start date) to (end date) were included. Two independent reviewers screened articles, extracted data, and assessed the quality of included studies using standard tools. The results show that non-pharmacological interventions are quite promising in preventing recurrence of gastric ulcers. Dietary modifications, such as avoiding spicy and acidic foods, and adopting a balanced diet rich in fruits and vegetables, are associated with a reduced risk of relapse. Lifestyle changes, particularly smoking cessation and reducing alcohol consumption, have shown a positive impact on healing ulcers and preventing recurrence. Stress management techniques, such as relaxation exercises and cognitive behavioral therapy, show potential benefits in reducing ulcer recurrence rates. Complementary therapies, such as acupuncture and herbal remedies, have shown mixed results, with some studies showing positive effects in preventing recurrence. Non-pharmacological interventions offer a valuable approach to preventing gastric ulcer recurrence. Dietary modifications, lifestyle changes, stress management techniques, and complementary therapies show promising results in reducing relapse rates. These findings highlight the importance of integrating non-pharmacological interventions into gastric ulcer management and prevention strategies. Further research is needed to validate these findings and explore optimal implementation methods.
Exploring the neutrophil-to-lymphocyte ratio as a prognostic biomarker in triple-negative breast cancer
Authors: Mittal Mistry  , Heer Shah  , Hemangini Vora
Published: May 2024

Triple-negative breast cancer is a subtype characterized by the absence of estrogen receptor, progesterone Receptor, and Human Epidermal Growth Factor Receptor 2 receptors, limiting treatment options primarily to chemotherapy due to lack of targeted therapies typically used for other breast cancer types, hence necessitating research for improved therapeutic strategies and outcomes. The neutrophil and lymphocyte percentages, absolute counts, and the ratio of neutrophils to lymphocytes were evaluated in peripheral blood of 81 patients with triple-negative breast cancer (TNBC) and 25 healthy controls. This study observed trend of high neutrophil percentage was observed in patients with positive lymph node status as compared to negative lymph node status. Significant high absolute neutrophil count was observed in patients with positive LN status, High BR score and presence of metastasis. A trend of high neutrophil to lymphocyte ratio was observed in patients with presence of perineural invasion, presence of necrosis, and patients with presence of metastasis.
Is Covid- 19 at home hospitalization a solution for better management of emerging and re-emerging infections?
Authors: Nora RIGHI  , S KATOUCHE  , R DJEBAILI
Published: May 2024

Covid 19 at home hospitalization (AHH) is an attractive alternative to full hospitalization for some patients. In this context, AHH provides close monitoring of Covid-19 patients at home, as well as their families, to relieve hospital overcrowding. Objective: To demonstrate the impact of extended covid-19 at home hopitalization (AHH) in patient management and its role in absorbing the epidemic explosion, and determine the epidemiological, clinical and psychological data of patients and their families with covid-19. Materials and methods: This was a prospective, longitudinal, exhaustive study of symptomatic patients suspected of having Covid-19 and their family and friends who met the inclusion and exclusion criteria; were identified by the triage centers, the public hospital (PHE) and the HUC Batna’s hospital; and were hospitalized in the expanded Covid-19 AHH unit at the PHE in Batna during the period from August 09, 2020 to April 30, 2021. Data collection was based on a pre-established data sheet containing epidemiological, clinical and psychological data. Results: From1449 patients reported, 190 refused to answer the questionnaire and 205 could not be contacted. We were able to compile 1054 covid-19 households, corresponding to 1054 patients meeting the inclusion and exclusion criteria, with 6607 family contacts. The average age in our series was 58.02 years, with a slight male predominance (sex ratio 1.1). 53.22% of our patients had one or more risk factors, the most frequently found being advanced age, cardiovascular pathologies and diabetes. Benign casess were the most frequent, 43.6% versus 25.6% of severe forms. Care was taken early in 56.3% of cases. The outcome was favorable in 88% of cases, with 12% of our patient’s requiring hospitalization, and 0 deaths. Conclusion: The value of this expanded Covid-19 AHH unit deserves to be supported and converted into a permanent unit to manage all emerging and re-emerging infections.
Establishment of a functional Orthopaedic Department in a Nigerian Teaching Hospital: The problems, peculiarities and prospects
Authors: A.C Nwachukwu
Published: May 2024

Establishing a functional orthopaedic department in a Nigerian teaching hospital faces challenges like staff attitude, equipment shortages, and regulatory hurdles. Solutions include infrastructure development, equipment procurement, and staff recruitment. Strategies for equipment shortages include capital investment and improved inventory management. Cultural competence training and community involvement address cultural factors impacting patient care. Quality control and innovation are crucial, necessitating audits and research collaborations. Ethical considerations, like patient consent, are paramount. Intramural Private Practice (IPP) integrates private and institutional healthcare, enhancing service delivery. Structured guidelines ensure operational integrity. Overall, a holistic approach focusing on staff management, quality, and patient-centred care is essential for a successful establishment. Keywords: orthopaedic department, challenges, solutions, cultural factors, quality control.
Epidemio-clinical aspects and neuro-meningeal tuberculosis prognosis in Batna
Authors: Nora Righi  , Amel Benbouza  , Rachida Djebaili  , Melissa Doumandji  , Bruno Lina
Published: May 2024

Neuromeningeal tuberculosis is rare, affecting around 1-2% of all tuberculosis cases and 5% of extra pulmonary tuberculosis cases. Our aim is to describe the epidemio-clinical, prognostic and evolutionary aspects of neuromeningeal tuberculosis. Materials and methods: To determine the spectrum of etiological agents of HIV-negative encephalitis and meningoencephalitis in Batna, we conducted a prospective study using an expanded testing approach. Patients were recruited from three departments (intensive care unit, infectious diseases department, pediatrics) during the period from April 1, 2012, to August 31, 2015. Data were collected according to the FLIPS case definition with a standardized form. We sought to identify etiological pathogens following a standardized procedure and to describe the epidemiological, clinical and biological features and outcomes associated with different causes. Results: A total of 141 patients with infectious encephalitis and meningoencephalitis were included in the study. Bacterial etiology was determined in 65/141 (46.1%) of whom 30 cases (21.3%) were of tuberculous origin; 21 confirmed and/or probable cases 9 possible cases with high clinical, epidemiological and radiological probability. The median age was 30.5 (0-83), predominantly female 12/18, 23.3% comorbidity with a frequency of motor deficits (86.7%) and psychiatric disorders (26.8%), respiratory involvement was present in 60% of cases, pleocytosis was present in 22/25 (73.4%). hyperalbuminorachy in 66. 7%, and hypoglycorachia in (46.7%). Anti-tuberculosis treatment was instituted in 90% of cases,17.6% were initially admitted to an intensive care unit, and the median length of hospital stay was 38.5 (1-146). death was identified in 46.6%, with 10% having sequelae. Conclusion: In our study, in addition to viruses, bacteria (especially intracellular) can be responsible for encephalitis and meningoencephalitis, in varying proportions. The most frequent and leading form of bacterial meningoencephalitis in adults is tuberculosis, the prognosis of which depends on early treatment.
A paradigm shifts in fintech and rural inclusion challenges in India
Authors: Cheenu Rathi  , Ajay Kr Varshney  , Shilpa Chaudhary  , Vaibhav Prakash  , Ankit Garg
Published: May 2024

FinTech abbreviates as financial technology. India being a developing country having largest population in the world by surpassing the china recently in April 2023. Continuing with conventional method of transaction, most of the people of such a populous country are standing in queue waiting for their turn for financial services. Is it feasible to bear such a time and economical loss arises as opportunity cost due to standing in queue rather than doing some other activity? Therefore, it become need of the time to adopt the advance technological way of doing transactions. Since 2015, India has witnessing its most aggressive phase of financial inclusion initiative ever seen anywhere in the world which brings nearly 330 billion citizens into formal financial sector which still increases to make it a crucial topic for research. In this research, we analyses the rural FinTech literacy requirement with all available means and impact of FinTech facilities on E-commerce and banking sector along with intermediaries role by adopting case study approach. With huge potential for FinTech, India can be the global FinTech super power but challenge is acceptance of FinTech with pace of technological advancement as well as with challenges and security loophole protection.
Analysis of the insecticidal effect of botanical extracts on mealybugs (Phenacoccus solenopsis)
Authors: Mariyam  , Newton Paul
Published: May 2024

The Cotton mealybug, also known as Phenacoccus solenopsis, poses a significant threat to agricultural productivity, particularly in cotton cultivation, where infestations cause substantial yield losses. This study examined the effectiveness of botanical extracts from neem (Azadirachta indica), clove (Syzygium aromaticum), black pepper (Piper nigrum), and bay leaf (Laurus nobilis) in controlling P. solenopsis. Neem extract showed the highest mortality effect at 86.6% followed by clove (68.3%) and black pepper (58.3%). Bay leaf extract had the lowest mortality effect at 36.6%. These findings highlight the potential of neem, clove, and black pepper extracts as effective options for managing P. solenopsis infestations in agriculture.
Impact of dealer profitability on dealer satisfaction: A context of Indian automobile industry
Authors: Sujay A. Bhalchandra  , Nilesh D. Shinde
Published: May 2024

The purpose of this study is to explore critical factors that defines the level of satisfaction and bond of relationship between Automobiles companies and their dealerships. Indian Automobile Industry is one of the world’s fastest growing Industry and the success of Auto companies is largely depend on their robust and healthy dealer network. In this paper, we attempt to identify critical factors which can influence the relationship of Manufacturer and Dealers. The research is based on a survey carried out in Pune region of Maharashtra, where we focused on identified critical factors of mutual relationship. It was also noted that new age Auto dealerships owners are looking forward for relationships beyond just return on Investment. Using statistical data analysis, we also attempt to identify most critical factors that can influence Dealer-OEM relations. These factors were return on Investment, Future growth potential, Support from OEM team, Involvement in policy decision making and supply of quality product. The results also indicate the roles and responsibility of an OEM in building strong relationship with its dealers to improve the sales.
Fluorescence spectra as an indicator of the influence of environmental conditions on fruit trees
Authors: Matilda Mema  , Kejda Kristo  , Emil Xhuvani
Published: May 2024

Molecular fluorescence spectra determine possible structural changes of these molecules and provide data (by comparing them with absorption ones) on the efficiency of solar energy utilization. Fluorescence emission spectra provide information on the functionality of the photosynthetic apparatus by means of two bands red F690 and beyond red F735. The objective of the study is to highlight possible changes in the organization and operation of the photosynthetic apparatus, induced by different radiations, in the leaves, for a variety of pear (Santa Maria), based on the characteristics of the two bands of emitted fluorescence. The Santa Maria variety was studied in the period of June.
Comparative analysis of machine learning algorithms for phishing website detection
Authors: Kumaraswamy S  , Saishravan Nitish Nayak  , Vinodh Kumar N  , Mohammad Waseem
Published: May 2024

As phishing assaults continue to pose a serious hazard in the digital world, trustworthy detection techniques are required. The effectiveness of machine learning techniques in detecting phishing websites is investigated in this study. The best-performing models were XGBoost and Multilayer Perceptrons (MLPs), which obtained test data accuracy of 90.4% and 90.3%, respectively. On the test data, the Random Forest and Decision Tree models showed competitive accuracies of 86.5% and 87.3%, respectively. SVMs, or support vector machines, performed admirably as well, obtaining an accuracy of 86.4% on the test set. Notably, with accuracy of 74.0% on the test data, the Autoencoder Neural Network demonstrated a restricted level of efficacy. These results highlight the effectiveness of XGBoost and MLPs in precisely detecting phishing websites, offering academics and practitioners in cybersecurity useful information.
The evolution of AI: What does the future hold in the next two years
Authors: AnandKumar Chennupati dKum
Published: May 2024

Artificial intelligence (AI) has evolved rapidly in recent years, transforming several industries and reshaping cultural norms. This article examines the current state of AI technology, focusing on significant trends and developments that have accelerated its growth. This paper sheds light on the evolving environment of AI innovation by examining current breakthroughs in machine learning, deep learning, and ethical concerns surrounding AI deployment. The following two years should see substantial advances in natural language processing, computer vision, and autonomous systems. Despite the excitement, difficulties such as ethical considerations, regulatory frameworks, and societal repercussions loom large, needing careful study and decisive action. This study aims to inform stakeholders about the transformative potential of AI and the methods required to properly navigate its growing landscape by conducting a balanced examination of opportunities and challenges.
The threat of artificial intelligence to elections worldwide: A review of the 2024 landscape
Authors: AnandKumar Chennupati
Published: May 2024

One area that might experience an immense transformation owing to the adoption of AI is the electoral system. Artificial intelligence (AI) holds tremendous potential for enhancing polls, campaign methods, and voter registration, but it also presents substantial challenges to the integrity of elections around the globe. This article discusses the political scene of 2024 and AI's role, balancing the pros and cons of AI deployment. Case studies of nations that have implemented AI for voting purposes are presented in the article, along with an analysis of the merits and disadvantages of these systems. The article goes on to warn of the perils of AI in elections and provides solutions to these concerns. It is of the most significant necessity to secure both the security and legitimacy of voting procedures, as the employment of artificial intelligence in elections is popular. This paper asks politicians, election authorities, and people in general to handle the challenges brought by AI in elections.
Artificial intelligence and machine learning for early cancer prediction and response
Authors: AnandKumar Chennupati
Published: May 2024

Worldwide, cancer claims more lives than any other disease. Although cancer detection, prognosis, and treatment have all advanced, one major obstacle is the lack of personalized, data-driven care. Artificial intelligence (AI), used to forecast and automate numerous malignancies, has emerged as a viable solution for increasing healthcare accuracy and patient outcomes. Artificial intelligence applications in cancer include risk evaluation, early detection, patient prognosis prediction, and treatment selection based on comprehensive data. Machine learning (ML), a form of artificial intelligence that allows computers to learn from training data, is very successful in predicting breast, brain, lung, liver, and prostate cancers. Indeed, AI and machine learning have outperformed physicians in predicting cancer. These technologies can potentially enhance the diagnosis, prediction, and quality of life of patients with a wide range of disorders, not just cancer. As a result, it is critical to enhance existing AI and ML technologies and create new programs to help patients. This article discusses the use of AI and machine learning algorithms in cancer prediction, including its present uses, future possibilities, and limitations.
Addressing the climate crisis: The synergy of AI and electric vehicles in combatting global warming
Authors: AnandKumar Chennupati
Published: May 2024

The climate catastrophe is a critical issue that requires quick and inventive solutions. The synergistic interaction between artificial intelligence (AI) and electric automobiles is one viable path for reducing global warming. This article investigates the relationship between AI and EVs in combating climate change. We begin by highlighting the severity and urgency of the climate situation, stressing the need for adequate mitigation solutions. We then investigate the role of electric cars as a greener alternative to typical fossil fuel vehicles, emphasizing their potential to cut greenhouse gas emissions in the transportation industry. Furthermore, we look at how AI technology might improve the efficiency and performance of electric cars, such as predictive maintenance, charging infrastructure optimization, and traffic management. By harnessing AI capabilities, EVs may function more efficiently, resulting in a considerable decrease in carbon emissions. Through this research, we highlight the necessity of cooperation between the AI and EV sectors and the need for supportive governmental frameworks to expedite the adoption of these technologies. Finally, this article argues for the revolutionary power of the AI-EV synergy in addressing global warming and creating a more sustainable future.
Paradoxical tuberculous reaction to anti-tnfα discontinuation: a complex case of miliary tuberculosis and macrophagic activation syndrome with hepatic manifestations
Authors: Imane ATMANI  , Maryame. el khayari  , Soukaina Srhiri  , Maria Lahlali  , Asmae Lamine  , Hakima Abid  , Amine ElMekkaoui  , Mounia El Yousfi  , Dafrlah Benajah  , Mohamed El Abkari  , Adil Ibrahimi  , Nada Lahmidani
Published: May 2024

Tuberculosis reactivation during anti-TNF-alpha therapy paradoxically worsened following reconstitution of pathogen-specific immune responses after cessation of TNFα antagonist treatment and initiation of anti-bacillary therapy. We report the case of a 46-year-old woman who was prescribed a tumor necrosis factor blocker (anti-TNF) for a relapse of Behçet's disease. The patient developed pulmonary miliary tuberculosis following the reactivation of latent tuberculosis, despite a normal pre-therapeutic work-up. Discontinuation of anti-TNF and initiation of anti-bacillary drugs triggered a paradoxical tubercular reaction (PTR). The diagnosis of paradoxical reaction to anti-tuberculosis drugs was evoked by the clinical and biological deterioration and the appearance of miliary cerebral tuberculosis and cerebral venous thrombosis after a period of clinical improvement. Although this phenomenon has been documented, it represents a major challenge for clinicians. The peculiarity of this case lies in its association with a macrophagic activation syndrome (MAS) with hepatic involvement, retained on clinical-biological and histological criteria. The overlap between MAS and PTR makes it difficult to diagnose these two entities with certainty. The patient responded favorably to moderate-dose systemic corticosteroid therapy with progressive degression, and the reintroduction of anti-tuberculosis drugs.This work aims to highlight the importance of close monitoring of TB patients on anti-TNFα therapy for early diagnosis and management of complications to improve the prognosis of these complex patients.
Thyroid function changes during growth hormone therapy in pediatric patients: a controlled study and review of recent data
Authors: Ashraf Soliman  , Fawzia Alyafei  , Nada Soliman  , Sohair Elsiddig  , Nada Alaaraj  , Noor Hamed  , Shayma Ahmed
Published: May 2024

Introduction: Growth hormone therapy is a cornerstone treatment for children with GHD and ISS. Its impact on the hypothalamic-pituitary-thyroid axis, however, has been a subject of ongoing research. This review compiles findings from several studies spanning three decades and contrasts them with recent data to enhance our understanding of thyroid function dynamics during GH therapy. Review of Literature: Early Observations (1992-2005) Pirazzoli et al. (1992) and Tang et al. (1997) were among the first to document changes in thyroid function due to GH therapy, noting enhanced peripheral conversion of T4 to T3 and a prevalence of subclinical hypothyroidism. Wyatt et al. (1998) reported significant decreases in T4 and increases in T3, indicating a notable shift in thyroid hormone levels early in GH therapy. Mid-Term Studies (2005-2015) Seminara et al. (2005) and Kalina-Faska et al. (2004) reported changes in thyroid function, particularly a decrease in T4 levels and a transient increase in fT3 during the early stages of GH therapy. · Recent Developments (2016-Present) Wang Ying and Liang Furong (2016) emphasized the need for vigilant monitoring of thyroid hormone levels, aligning with Zheng et al. (2014) who noted improvements in lipid metabolism without significant thyroid function impacts. Glynn et al. (2017, 2018) and Kucharska et al. (2021) focused on the complexities of the biological effects of GH-induced changes in thyroid hormones. Comparison with our Data Our recent study reveals subtle changes in thyroid function in GH-treated children with GHD and ISS. We observed a slight decrease in mean FT4 and an increase in mean TSH in the GH treatment group, stable TSH and decreased FT4 in the ISS treatment group, and significant decreases in both FT4 and TSH in the no-treatment group. These findings corroborate the trend seen in earlier studies, highlighting the multifaceted nature of thyroid function changes during GH therapy. Conclusions: The review underscores that GH therapy can significantly influence thyroid function, necessitating regular monitoring of thyroid hormone levels. The variation in thyroid responses suggests a complex interaction between GH therapy and the hypothalamic-pituitary-thyroid axis, which may be influenced by factors like age, severity of GHD, and duration of GH treatment.
A case report of urogenital schistosomiasis
Authors: Alae Zouhair  , Zackaria Ba  , Aboubakry Sow  , Rhyan ouaddane Alami  , Mustapha Ahsaini  , Soufiane Mellas  , Jalal Eddine EL Ammari  , Med Fadl Tazi  , Med Jamal EL Fassi  , My Hassane Farih
Published: May 2024

Schistosomiasis, a parasitic disease widespread in tropical regions, is primarily caused by Schistosoma haematobium. Although rare in Western countries like France, it remains a major public health issue. Diagnosis relies on detecting the parasite's eggs in urine and bladder biopsies. Prevention involves awareness campaigns, annual treatment with praziquantel in high-prevalence areas, and treatment of infested waters. The case of a 17-year-old Senegalese girl presenting with lower urinary tract symptoms (LUTS) was reported. Analyses revealed the presence of schistosomiasis eggs in her urine. After treatment with praziquantel and corticosteroids, she developed acute urinary retention requiring catheterization. Further examinations confirmed urogenital schistosomiasis, necessitating surgical intervention.
Adherence of Candida albicans to fibrin-clot matrices in a rat model for type 2 diabetes
Authors: Balbina J. Plotkin  , Monika I. Konaklieva
Published: May 2024

Individuals with type 2 diabetes are at increased risk for the development of infective endocarditis and septic thrombosis. Adherence to fibrin clot matrices by Candida albicans is the initial step in initiation of the infective processes. Clots made from lean (Fa/fa) and obese (fa/fa) Zucker rat plasma were used to measure adherence of yeast grown at environmental temperature and human body temperature. Adherence to clots by C. albicans was influenced both by source of plasma and temperature of yeast growth. Amphotericin B was effective in diminishing the candidal binding to lean but not obese clots. The degree of fungal surface hydrophobicity did not correlate with adherence to clots. However, Candida adherence to clots from both lean and obese Zucker rats was inhibited by the pretreatment of cells with mannose. These findings indicate that treatment of thrombi-associated candidal infections with ergosterol-targeting drugs e.g., amphotericin B alone in hypercholesterolemic individuals may have decreased clinically efficacy.
A healthy habitual score for dietary intake is associated with primary dysmenorrhea among adolescent school girls
Authors: Payel Pramanik  , Purushottam Pramanik
Published: May 2024

Background: Primary dysmenorrhea is one of the most common gynecological complaints among adolescent and young females in their reproductive age that affects their daily activities and social life. Nutritional habits are considered as risk factor for primary dysmenorrhea. ‘Thus the aim of our study was to assess the relation between healthy habits score for dietary intake and prevalence of primary dysmenorrhea. Methods: The present study was conducted on 432 adolescent school girls (218 girls with nil to mild dysmenorrhea and 214 girls with moderate to severe dysmenorrhea). Healthy habitual scores (HHS) was calculated from 5 modifiable dietary intake habits considering high risk habit as ‘0’ and low risk habit as ‘1’ giving a composite score ranging from 0 to 5. We classified the healthy life style score into three category: 0-2 as low; 3 as medium and 4-5 as high. Correlation between HHS and its components with incident of primary dysmenorrhea were evaluated. HHS and risk of primary dysmenorrhea were evaluated using logistic regression analysis. The significance level of the all the tests were considered at a level of 0.05. Results: Significant correlation was obtained between incident of primary dysmenorrhea and all tested habits. Magnitude of correlation was higher for HHS than individual habit. Among tested habitual factors sugar intake, skipping breakfast and frequency of junk food intake was positively correlated where as negative correlation was obtained between primary dysmenorrhea and dietary intake of vit-E and calcium. Considering low HHS as reference group odd ratio significantly low in medium and high HHS groups. Thus risk of primary dysmenorrhea was more among adolescent girls those led unhealthy dietary habits like take more sugar, frequently take junk foods and skipping breakfast and take vit-E and calcium below recommended amount. Conclusion: Avoiding of Junk food, skipping breakfast and intaking of vit-E and calcium as per recommended amount and restricting sugar intake is recommended as a healthy dietary habit to minimize the risk of primary dysmenorrhea.
Formulation and evaluation of emulgels loaded with microspheres containing Baricitinib
Authors: P. Laxmi  , G. Vijayalakshmi  , V. V. Basava Rao
Published: May 2024

The main objective of the present research work was to formulate and evaluate transdermal gel loaded with microspheres of Baricitinib to increase bioavailability and to reduce the dosing frequency and to improve patient compliance. Gel loaded with microspheres of Baricitinib was prepared by taking different ratios and grades of Carbopol polymers. The prepared formulations (F1–F9) were evaluated for pre-formulation studies, percentage yield, particle size, content Uniformity, drug content entrapment efficiency and in vitro dissolution studies. The optimized gel loaded with microspheres of F8 formulation (drug: Carbopol 974polymer in 1:1 ratio) is more effective compared to all formulations. The prepared gel showed acceptable physical properties such as particle size of (126.5 microns), percentage yield of (96.5%), content uniformity (97.8), and drug content entrapment efficiency (90.5%). In vitro dissolution studies have shown 100.1% drug release in 12 h. With the optimized formulation Baricitinib emulgels are formulated using different grades and ratios of Carbopol and optimized microsphere formulation F8. The Emulgel formulation F7 showed the acceptable results with a yield of 92.3%, Drug content (100.2%), Spread ability (13.38 g.cm/s), Viscocity (112.3 cP), pH off 6.05 and it was observed that formulation F7 showed 100.2% drug release within 12 hours. All the results show that the gel loaded with microspheres of Baricitinib can be effectively used for the treatment of viral infections like small fox.
Problematics of Arabic Learning through e-Learning and Its Solution at Senior High School
Authors: Dedi Mulyanto  , Sarah Fauziah  , Arifin Laode Muhammad Alfateh
Published: May 2024

The objectives of this study are: 1. To explain the problems of learning Arabic through E-learning for class XI IPA at MAN 1 Sragen, Central Java, Academic Year: 1441-1442 H, 2. To explain about solving these problems. This type of research is a qualitative descriptive study. In collecting the data, the researcher used three methods, namely: the interview method, the observation method, and the documentation method. Researchers used Miles and Huberman's analysis with three steps: data collection, data presentation, and conclusion. The results of the data analysis stated that: 1) Arabic learning problems through E-learning for class XI IPA consists of several aspects: a) Problems in terms of teachers: The teacher leaves several steps contained in the language learning method Arabic through E-learning, b) Problems in terms of students: Lack of student interest in learning Arabic through E-learning, c) Problems in terms of E-learning media include: E-learning media is a learning application that requires supporting tools, such as Android, Computers, and Internet Signals, 2) Problem-solving in the learning problem consists of several aspects: a) Problem-solving from the teacher's point of view. The teacher must use the Arabic teaching method through E-learning properly and correctly. b) The solutions to students' problems are the teachers must increase student motivation in learning Arabic through E-learning, c) Completion in terms of E-learning media. Teachers and students must prepare supporting tools in the Arabic learning process through E-learning.