bluuebunny/crossref_metadata_2025 huggingface dataset:
Water security decision-making issues in Central Asia
Authors:   Academy of Public Administration under the President of the Republic of Kazakhstan, Prniyazova A.E. , Dalelkhan A. ,   L.N. Gumilyov Eurasian National University, Gusseinova H. ,   Institute for Development and Diplomacy ADA University
Published: February 2025

The article is devoted to the study of the sources of endogenous uncertainty in water resources management on the example of the Central Asian states. The study focuses on endogenous uncertainties arising in the decision-making system and identifies key factors for their mitigation, including data availability and analysis, sustainable infrastructure and expanded capacity. The study recognizes the potential increase in exogenous uncertainty caused by limited cross-border cooperation, the effects of climate change and the growing need for water. He emphasizes the importance of recognizing and understanding the nature and consequences of uncertainties. Thus, the Central Asian countries can make more informed decisions and work towards achieving sustainable water security in the region.

In the Central Asian republics, water security is becoming increasingly important due to the uncertainty and risks associated with climate change and the growing demand for water. This is compounded by growing disputes over important complex transboundary river basins, interconnected water and energy infrastructure in the Aral Sea basin, water distribution between riparian countries and the vulnerability of water resources to climate change. It is assumed that the adoption of effective decisions at all levels concerning the allocation and management of water resources will contribute to achieving water security.
Catch Me If You Can: A Modified GAN Architecture Leveraging SIFT and Feature-matching for Highly Stable Training
Authors: Asraa Saeed  , Ahmed A. Hashim
Published: February 2025

Generative Adversarial Networks (GANs) traditionally consist of two networks: a generator that creates new samples and a discriminator that evaluates the authenticity of these samples. Both networks are trained together competitively to generate samples indistinguishable from real data. This paper proposes a novel GAN architecture, Frank-GAN, which comprises two generators and one discriminator. The inspiration for this work comes from the movie "Catch Me If You Can." In the film, the main character, Frank, deceives the government by forging checks and certifications. After apprehending him, the government decides to utilize his expertise by appointing him to banking security to catch other forgers. Similarly, the second generator in Frank-GAN is specially trained using the feature-matching technique to match the activations of hidden discriminator-layer feature values between real and fake images, to enhance the GAN's effectiveness and stability. Unlike traditional GANs that rely on random noise as input, the input to the second generator consists of keypoints that are extracted from real images using a Scale-invariant feature (SIFT). Frank-GAN was evaluated on the CelebA and The Oxford 102 Flower datasets. The Fréchet inception distance metric (FID) improved from 48.5 to 7.04 on the CelebA dataset and from 49.84 to 6.04 on the Oxford 102 Flower dataset, while the inception score (IS) increased significantly from 2.70 to 18.68 on the CelebA dataset, when using Frank_GAN compared to traditional DCGANs. This demonstrates the good performance of Frank-GAN in generating high-quality and realistic images at 128×128 size.
Fabrication of MWCNT/S/AC Battery Electrodes Using the Doctor Blade Method with Cyclic Voltammetry (CV) Testing of KCL Electrolyte Variations to Determine Specific Capacitance Values
Authors: Putri Endah Puspita Sari  , Agus Subagio  , Ngurah Ayu Ketut Umiati
Published: February 2025

The increasing demand for energy storage has led researchers to try to find cathode materials that have the ability to increase specific capacitance. Sulfur-based electrodes are considered the right choice to overcome this problem; however, there are still weaknesses due to the insulating properties of sulfur and polysulfides. This study uses MWCNT and activated carbon materials, which are considered to be able to increase conductivity and minimize sulfur dissolution into the electrolyte, which affects the specific capacitance value. Electrolytes as a means of ion transport also greatly affect the performance of battery electrodes. Electrochemical analysis was carried out by conducting CV tests using KCl electrolyte solutions at concentrations of 0.05 M, 0.25 M, and 0.5 M. The results showed that the use of KCl electrolyte solutions on the electrodes showed an increase in specific capacitance values along with increasing electrolyte concentrations. With each concentration, the specific capacitance values were 0.1725 F/g⁻¹, 0.3593 F/g⁻¹, and 0.5336 F/g⁻¹.
Duality Relations of Fractional Order Transforms
Authors: S.A.Tarate  , K.A.Kshirsagar  , A.P.Bhadane
Published: February 2025

The authors of the article discussed the duality relations of fractional Laplace transforms with kamal, Laplace-Carson, Aboodh, Sumudu, Elazaki, Mohand, Sawi, and natural transforms of fractional orders in this article. Tabular Presentation of Laplace Transforms, Laplace-Carson Transforms, Aboodh Transforms, Sumudu Transforms, Natural Transforms, Elazaki Transforms, Mohand and Sawi Transforms of Fractional Orders of Some Basic Mathematical Functions.
ПСИХОТЕХНОЛОГІЇ ВИРІШЕННЯ КОНФЛІКТІВ РОЗРОБНИКІВ СИСТЕМ ЗАХИСТУ ІНФОРМАЦІЇ В УМОВАХ КІБЕРЗАГРОЗ
Authors: ЧЕРНЯКОВА Олеся
Published: February 2025

Мінливі умови сучасності, спричинені цифрою трансформацією та інтенсифікацією інформаційного середовища значно підвищують складність роботи фахівців з інформаційної безпеки, що, у свою чергу, провокує виникнення міжособистісних і професійних конфліктів. Високий рівень стресу, необхідність оперативного реагування на загрози та багатозадачність створюють сприятливе підґрунтя для конфліктних ситуацій у командах, які розробляють та впроваджують системи захисту інформації. Мета. Важливим викликом для сучасної науки є визначення ефективних психотехнологій для діагностики, попередження та вирішення конфліктів серед розробників систем інформаційної безпеки, з урахуванням специфіки їхньої професійної діяльності. Основна увага, на нашу думку, має бути приділена аналізу впливу когнітивних, емоційних і соціальних чинників на процеси комунікації та співпраці в команді. Стаття присвячена теоретичному аналізу психотехнологій вирішення конфліктів серед фахівців з інформаційної безпеки в умовах зростаючих кіберзагроз. В роботі розглянуто сутність ключових понять: «кіберзагроза», «конфлікт», а також визначено специфіку виникнення та протікання конфліктів у професійних колективах розробників систем захисту інформації. Особливий акцент зроблено на впливі стресогенних чинників, спричинених кіберзагрозами, на психологічний клімат у командах, що займаються захистом інформації. Методологічною основою дослідження є міждисциплінарний підхід, який поєднує положення психології конфлікту, кібербезпеки та організаційної психології. Теоретичний аналіз дозволив виявити основні джерела конфліктів серед фахівців у сфері інформаційної безпеки, зокрема конкуренцію за ресурси, напруження через високий рівень відповідальності та ризиків, а також проблеми міжособистісної взаємодії в умовах інтенсивної роботи. На основі проведеного аналізу розроблено низку практичних рекомендацій, спрямованих на профілактику конфліктів. Зокрема, запропоновано методики підвищення стресостійкості фахівців, розвиток навичок конструктивної комунікації, впровадження програм тімбілдінгу та створення сприятливих умов для ефективної роботи команд. Особлива увага приділена використанню психотехнологій, що сприяють своєчасному розпізнаванню та вирішенню конфліктів, запобіганню їхньому загостренню та зниженню негативного впливу на професійну діяльність. Результати дослідження можуть бути використані як основа для подальших прикладних розробок у сфері організації діяльності команд фахівців з інформаційної безпеки, а також для розробки навчальних програм, спрямованих на формування стресостійкості та підвищення ефективності командної взаємодії в умовах сучасних кіберзагроз.
ВИКОРИСТАННЯ МЕТОДІВ МАШИННОГО НАВЧАННЯ ДЛЯ АДАПТАЦІЇ ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ ДО РІЗНИХ ОБЧИСЛЮВАЛЬНИХ ПЛАТФОРМ
Authors: БЕРДНИК Михайло , СТАРОДУБСЬКИЙ Ігор
Published: February 2025

Актуальні виклики у сфері розробки програм, зумовлені різноманітністю апаратних архітектур, та запропоновані шляхи їх подолання за допомогою адаптивних компіляторів. В роботі розглядається створення адаптивних компіляторів, які використовують методи машинного навчання для автоматичної оптимізації та адаптації програмного забезпечення до різних обчислювальних платформ. В роботі також наводяться приклади застосування адаптивних компіляторів у мобільних та хмарних обчисленнях, де вони демонструють суттєве підвищення продуктивності та ефективності програмного забезпечення. Метою роботи є створення адаптивних компіляторів, використовуючи інтеграцію методів машинного навчання на всіх етапах компіляції – від аналізу вхідного коду до генерації машинного коду. Наукова новизна полягає в інтеграції методів машинного навчання в процес компіляції, що дозволяє адаптивним компіляторам автоматично налаштовувати оптимізацію коду для різних обчислювальних платформ. Це рішення забезпечує динамічне налаштування компіляції, підвищує продуктивність програм та знижує потребу у ручному налаштуванні для нових архітектур. Висновки. Проведений аналіз підкреслює ефективність адаптивних компіляторів, які завдяки машинному навчанню забезпечують автоматичну оптимізацію коду, підвищуючи продуктивність та ефективність програмного забезпечення на різних платформах. Запропонований підхід спрощує адаптацію програм, знижує витрати на розробку та дозволяє зосередитись на функціональності продуктів.
РОЗРОБКА ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ ДЛЯ ЗБИРАННЯ ФЕНОТИПІЧНИХ ДАНИХ НАСІННЯ СОНЯШНИКУ
Authors: ВЕДМЕДЄВ Станислав
Published: February 2025

Головним напрямком в селекції соняшнику є підвищення якості насіння й промислових характеристик, що є важливими для споживача. Для оцінки якості насінини може бути використано оцінку за фенотипом. Фенотипування дозволяє створити формалізований підхід до оцінювання, що включає перелік ознак, форму точного опису та засоби для вимірювання цих характеристик. Метою представленого дослідження є розробка програмного забезпечення вивчення морфологічних ознак насінини соняшнику за фотозображеннями, а саме метричних характеристик, форми та забарвлення насінини. Методологія. Розроблені програми базуються на точному математичному обрахунку, що забезпечує точність створених описів. Програмні продукти аналізу зображень розроблено зі застосуванням мови програмування Python. Програма розрахунків розроблена в середовищі PyCharm Community Editor 2022.2.4 з використанням бібліотек: os, cv2, imutils, numpy, time, Pool. Cv2-для обробки зображення. Дослідження проводилося на колекції фотозображень насінини соняшнику, що містить 3000 фотографій 250 ліній соняшнику та створена фахівцями Інституту олійних культур Національної Академії Аграрних Наук України. Наукова новизна полягає в тому що вперше було розроблено програми для аналізу зображення насіння соняшнику з урахуванням біологічного різноманіття насіння. Вони вперше дали змогу описати досі якісні ознаки насіння у якості таблиць кількісних показників. Висновки. У результаті проведеного дослідження розроблено модель для вимірювання метричних характеристик та форми насінини, а також програмне забезпечення, яке складається з програм розпізнавання метричних характеристик насіння, форми та смугастого забарвлення насінини. Розробки можуть бути використані для аналізу фотозображень насінини, яке зроблено на стаціонарному приладі з детермінованими параметрами в умовах лабораторії. Отриманні результати є важливою складовою для селекційної роботи по створенню нових високопродуктивних гібридів, сортів та ліній соняшнику. Зараз розробка використовується селекціонерами та генетиками Інституту олійних культур Національної Академії Аграрних Наук України в ході наукової селекційної роботи.
IMPORTANT ISSUES OF DATA PROCESSING AND PROTECTION IN DISTRIBUTED SYSTEMS
Authors: DOROZHYNSKYI Serhii , TUPKALO Vitaliy , SHCHERBYNA Yuriy
Published: February 2025

The purpose of this article is to explore the critical aspects of big data processing in distributed networks as a contemporary challenge in ensuring cybersecurity. Special attention is given to issues of confidentiality, integrity, and availability of data in multi-user environments with high interaction complexity. The methodology of the study involves a comprehensive approach, including the analysis of threats and vulnerabilities specific to distributed architectures such as cloud technologies, peer-to-peer networks, and decentralized infrastructures. Key issues such as asynchronous data access, limited computational resources, operation synchronization complexity, and risks of data interception during transmission are examined. The study evaluates modern cryptographic approaches, including homomorphic encryption, distributed key management mechanisms, and privacy-preserving protocols. Additionally, the application of machine learning and deep learning algorithms is explored for anomaly detection in system behavioral models in real-time. The scientific novelty of the research lies in the systematization of threats and vulnerabilities inherent to distributed data processing systems and the development of effective approaches to neutralize them. For the first time, a comprehensive approach to the use of blockchain technologies is proposed as a means of ensuring transparent auditing of events and tracking transactions in distributed environments. The conclusions provide practical recommendations for integrating modern cryptographic methods, distributed key management mechanisms, blockchain technologies, and machine learning algorithms to build resilient cybersecurity systems. The findings are of practical significance for ensuring the protection of big data in distributed networks and improving the effectiveness of responses to potential threats.
Il DM77 nell'Azienda USL-IRCCS di Reggio-Emilia: tra passato, contingenze e progettualità future
Authors: Bergamaschi Mara , Castellini Giada Carola , Lega Federico , Maggioni Elena , Violi Federica
Published: February 2025

L'articolo analizza lo stato di attuazione del DM 77/2022 nell'AUSL-IRCCS di Reggio Emilia, esaminando la riorganizzazione dei servizi sanitari territoriali attualmente in corso. Vengono esplorate le sfide e le soluzioni adottate in un territorio già orientato verso modelli integrati come Distretti e Case della Salute. Tra le azioni implementate dall'Azienda si evidenzia l'attivazione di setting di cura dedicati alla medicina di iniziativa, come Centrali Operative Territoriali e Ospedali della Comunità, la formazione del personale medico e sanitario, e il potenziamento dell'assistenza domiciliare.Tecnologie innovative, collaborazione multidisciplinare e multiprofessionale e coinvolgimento del terzo settore risultano essere elementi chiave per rispondere in modo integrato ai bisogni di salute e valorizzare i professionisti coinvolti. La chiave di lettura del caso va oltre l'attuazione del DM 77, comprendendo una transizione valoriale nella politica sanitaria per sviluppare un servizio pubblico più pronto ad affrontare le sfide contemporanee.
Protezione del minore versus protezione sociale?
Authors: Gallo Giovanni
Published: February 2025

A fronte delle nuove forme di devianza minorile e del crescente allarme sociale, il sistema di giustizia penale minorile è ancora in grado di corrispondere alle esigenze per cui è preposto? Oppure la scelta di politica criminale, varata con il d.l. Caivano e protesa a un maggior ricorso a misure detentive/retributive, deve ritenersi necessaria? La risposta a questi interrogativi deve essere individuata in una prospettiva costituzionale, dove i doveri di protezione della gioventù non vengono meno a fronte dell'agito deviante e pertanto le misure di tipo detentivo devono permanere quali extrema ratio. La sfida della giustizia minorile rimane attuale: saper contemperare l'esigenza di protezione della società con quella del minore deviante, non rinunciando a un approccio interdisciplinare capace di rielaborare il quadro personologico del minore, predisponendo e attuando un progetto idoneo a corrispondere ai suoi bisogni di crescita.
Ricerca-intervento, sociologia dell'azione e processi di soggettivazione nelle trasformazioni del lavoro e della vita sociale
Authors: Di Nunzio Daniele , Toscano Emanuele
Published: February 2025

Questo articolo presenta una riflessione di ordine teorico e metodologico sulla ricerca-intervento nell'ambito della sociologia dell'azione e del soggetto (Touraine 1978, 1992) sulla base di alcune esperienze di ricerca condotte nel contesto sindacale condotte negli ultimi anni. Partendo dalla prospettiva teorica definita da Touraine e dai ricercatori e dalle ricercatrici che per oltre trent'anni hanno animato la vita intellettuale del Centre d'Analyse et D'Intervention Sociologique (CADIS), l'articolo approfondisce quattro dimensioni che caratterizzano dal nostro punto di vista la ricerca-intervento: a) la prospettiva della soggettivazione; b) l'attivazione degli attori e il ruolo trasformativo della ricerca-intervento; c) gli orientamenti valoriali; d) il dialogo e l'elaborazione collettiva. In particolare, si evidenzia il ruolo determinante che la ricerca-intervento assume per la comprensione dell'epoca moderna, poiché cerca di fornire agli attori sociali gli strumenti per riflettere criticamente attraverso un processo inter-soggettivo. Infine, l'articolo si sofferma sulle sfide di ordine metodologico nello studio delle trasformazioni del lavoro e della vita sociale.
Disseminating a design vision: the Soviet collective housing and its international fortune
Authors: De Magistris Alessandro
Published: February 2025

Soviet research on collective housing developed rapidly between the end of the NEP and the first pjatiletka.At the dawn of the 1930s, these experiments were interrupted by a series of legislative measures that redefined housing policies, sanctioning their incompatibility with the social and economic directions that accompanied the Stalinization of the regime.However, many of the solutions developed in this phase, banned in the USSR, experienced a significant international diffusion.Through many reformulations, in the pre-war period and in the first decades of the post-war period, they fueled one of the most relevant circulation phenomena of design vision and settlement organization of the XX century.Some significant passages of this story are retraced, starting from the pivotal case of the famous ‘transitional' house of Dom Narkomfina.
An assessment of interobserver agreement on lesion size, morphology and clinical phenotype in cutaneous leishmaniasis caused by Leishmania aethiopica in Ethiopia
Authors: Mohammed Amel Beshir , Mohammed Fewzia Shikur , Zewdu Feleke Tilahun , Nigusse Shimelis Doni , Lambert Saba , Marks Michael , Walker Stephen L. , Gadisa Endlamaw ,   SHARP Collaboration
Published: February 2025

Introduction Cutaneous leishmaniasis (CL) remains a major public health challenge, especially in endemic regions like Ethiopia, where an estimated 40,000 new cases occur annually. Effective treatment evaluation for CL relies on consistent clinical assessments, yet variability in lesion descriptions can complicate reliable outcome measures. Methods We conducted an inter-reliability study of clinicians’ evaluations of CL lesion morphology and size at ALERT Hospital, Addis Ababa. Twelve clinicians independently examined 12 patients with parasitologically confirmed CL, each clinician assessing lesion morphology, size, and severity. Results We found high consistency in reporting major morphological categories (e.g., plaques) but significant variability in secondary features like dyspigmentation and scale, as well as mucosal involvement. Lesion size measurements showed limited variability, suggesting its reliability as a potential measure for future clinical trials. Disparities in severity assessments highlight the need for a standardized scoring system in CL. Discussion Our findings underscore the importance of training for consistent, high-quality clinical evaluations of CL and suggests that lesion size could be a reproducible outcome measure in treatment efficacy trials.
Social Learning in the Digital Age: An Analyze of the Benefits of Twitter Platform from Vygotsky’s Perspective
Authors: Dr. Hend Abdullah Bamalan
Published: February 2025

This study examines the theoretical foundations of Vygotsky’s social constructivist theory of learning and explores its alignment with using Twitter as a pedagogical tool. Utilizing a literature review methodology, the research found three key aspects in which the Twitter platform reconciles with Vygotsky’s theoretical framework: co-construction of knowledge, active learning, and scaffolding. The findings reveal that Twitter positively impacts higher education by enhancing students’ academic achievement, engagement, and reflective practices. Additionally, the platform promotes a sense of community, promoting feelings of belonging and connectedness among students. These findings highlight the potential of Twitter as a supportive tool in contemporary educational settings grounded in social constructivist principles. Among the main takeaways for educational practitioners, are the importance of considering students’ prior Twitter experiences and providing extra resources for those without much experience in the platform, including ways to monitor their progress, along with the importance of integrating the use of Twitter in pedagogically sound manners, focusing on specific learning goals, and leading with clear rules and guidance, making expectations absolutely clear. Other important considerations are focusing on the creation of course designs that are useful for students, using strategies such as the separation of academic and personal accounts, as well as streamlined ways of accessing Twitter outlines and content in general that is posted on the platform.
Diet of the Dattatreya night frog Nyctibatrachus dattatreyaensis from the central Western Ghats, India
Authors: ARPITHA JOY , GANESH SHAMA
Published: February 2025

The Dattatreya night frog Nyctibatrachus dattatreyaensis, found in the Chandra Drona Parvatha massif, is a stream-dwelling, evolutionarily distinct and globally Endangered species threatened by increasing habitat loss and alteration. We examined the stomach contents of 104 individuals, from ten different streams, of which 42 had prey in their stomachs. The prey items were in 12 orders across 4 classes, mainly dipterans, hymenopterans and lepidopterans. The frog exhibits a passive foraging mode, has a moderate trophic niche breadth (Bst = 0.43), and may have a preference for agile prey. Apart from this, there were plant materials, sand grains and plastic debris found in the stomach contents, with 0.82 mm³ of plastic debris found in eight individuals across three streams. The presence of plastic debris indicates the impact of anthropogenic activities leading to a form of habitat degradation. The data presented indicates the need for immediate and efficient conservation strategies to be put in place for this understudied species.
Scoping the Utility of Lentiviruses as an Aid in Oncologic Treatment and Vaccine Development: A Narrative Review
Authors: Aayush
Published: February 2025

Lentiviruses have emerged as the “go-to” when it comes to viral vectors. Their capacity to effectively introduce therapeutic genes into specific cells, such as cancer cells, is extremely promising. The review also looks at the use of lentiviruses in the creation of innovative vaccines. Researchers hope to trigger a strong immune response against cancer cells by encoding tumour-associated antigens or immune stimulatory chemicals into the viral vector. The possible benefits and difficulties of using lentiviruses in various fields are carefully evaluated. They have a high capacity to deliver large antigens and have low anti-vector immunity, making them an attractive choice for immunizations targeting various cancers and infectious diseases. Ultimately, the study clarifies future approaches and existing research endeavours aimed at maximising lentiviral vectors' potential for cancer medicines and vaccines.
Bangladesh Journal of Infectious Diseases, December 2024;11(2):152-159
Infection Rate in Laparoscopic Surgery in Low-Resource Facilities in Bangladesh
Authors: Saha Pankaj Kumar
Published: February 2025

Abstract Not Available
Bangladesh Journal of Infectious Diseases, December 2024;11(2):235-236
Jälkikapitalistinen yrittäjyyskasvatus: Kritiikin umpikujat ja toisintekemisen mahdollisuus
Authors: Alhojärvi Tuomo , Kainulainen Mikko
Published: February 2025

Yrittäjyyskasvatus on saanut kasvavaa huomiota osakseen sekä opetuskäytäntönä että tutkimuskohteena. Suomessa kriittinen tutkimus on nostanut esiin perusteltuja huolenaiheita yrittäjyyskasvatuksen ideologisista painotuksista ja ristiriitaisista vaikutuksista; kuitenkin kritiikin anti vaihtoehtoisten opetuskäytäntöjen ja toimintamallien suhteen on jäänyt vähäiseksi. Etsimme syitä yrittäjyyskasvatuksen kritiikin ja pedagogisten sovellusten väliselle kuilulle keskittyen suomenkielisen kriittisen tutkimuksen performatiiviseen, todellisuutta muokkaavaan työhön. Tutkimme teoreettis-metodologisia umpikujia, joita kriittinen tutkimus tuottaa nojatessaan tietokykykapitalismin ja uusliberaalin hallinnan käsitteisiin: Yhtäältä yrittäjyyskasvatuksen talous näyttäytyy kriittisessä tutkimuksessa yksioikoisen kapitalistisena maisemana. Toisaalta kysymys vallasta palautuu vallitsevaksi ja määrääväksi ymmärrettyyn hallintaan, mikä ei ruoki toimijuuden eläviä mahdollisuuksia. Vaikka kriittinen yrittäjyyskasvatustutkimus tuottaa arvokkaita yhteiskunnallisia diagnooseja, se ei kykene yhtä monipuolisesti tunnistamaan toisintekemisen mahdollisuuksia. Muotoilemme vaihtoehdon kritiikin umpikujille lähtien liikkeelle feministisen talousmaantieteen alalla kehitetystä moninaisen talouden lähestymistavasta. Se tarjoaa tulkintoja taloudesta ja vallasta, jotka auttavat hahmottamaan heterogeenista keskinäisriippuvuutta ja jokapaikkaista toimijuutta. Korostaen yrittäjyyskasvatuksen tulkinnanvaraisuuden vaikutuksia luonnostelemme suuntaviivoja toimintatavalle, joka avartaa yrittäjyyskasvatuksen talouskäsitystä ja konkretisoi kasvatuskäytäntöjen potentiaalia.
DIREITO À SAÚDE E À EDUCAÇÃO: A INTERCONEXÃO DA REDE DE CUIDADO AO TRANSTORNO DO ESPECTRO AUTISTA DE ITAJAÍ (SC)
Authors: Meller Vanderléa Ana , Da Silva Claudio , Liebel Graziela
Published: February 2025

As pessoas com Transtorno do Espectro Autista (TEA) necessitam de atendimento especializado para o desenvolvimento humano e relações de cuidado. O objetivo desse estudo busca compreender a interconexão da rede de cuidado ao Transtorno do Espectro   Autista (TEA) como estratégia para a garantia do direito à educação e à saúde. Trata-se de uma pesquisa de abordagem qualitativa, com base no método da hermenêutica fenomenológica e com delineamento documental. Os resultados evidenciam que a interconectividade da rede de cuidado ao TEA é fundamental para que as instituições de saúde e educação estabeleçam fluxos inclusivos. Um Sistema Integrado de Informações sobre o Autismo (i.TEA) foi criado para o registro dos dados das pessoas e instituições, com organização da agenda de atendimentos, colaborando com a gestão institucional e o acesso das pessoas aos serviços. O i.TEA foi constituído a partir de requisitos fundamentais para possibilitar a inclusão equânime dos direitos à educação e à saúde.
 
PALAVRAS CHAVE: Direito; Educação; Saúde; Rede de Cuidado; Transtorno do Espectro Autista.
RIGHT TO HEALTH AND EDUCATION: THE INTERCONNECTION OF THE CARE NETWORK FOR AUTISTIC SPECTRUM DISORDER IN ITAJAÍ (SC)
ABSTRACT
People with Autism Spectrum Disorder (ASD) need specialized care for human development and caring relationships. The objective of this study seeks to understand the interconnection of the care network for Autism Spectrum Disorder (ASD) as a strategy to guarantee the right to education and health. This is a research with a qualitative approach, based on the phenomenological hermeneutics method and with a documentary design. The results show that the interconnectivity of the ASD care network is fundamental for health and education institutions to establish inclusive flows. An Integrated Autism Information System (i.TEA) was created to record data on people and institutions, organizing the service agenda, collaborating with institutional management and people's access to services. i.TEA was created based on fundamental requirements to enable the equitable inclusion of the rights to education and health.
 
Keywords: Law; Education; Health; Care Network; Autism Spectrum Disorder.
Pelatihan Penguatan Literasi dan Numerasi dalam Pemulihan Pembelajaran pada SMP di Kabupaten Ogan Ilir
Authors: Suratmi Suratmi , Ilhami Akmillah , Azka Dea Alvionita , Defliyanto Defliyanto , Nopriyanti Nopriyanti , Nurhasan Nurhasan
Published: February 2025

This community service activity aims to strengthen literacy and numeracy competencies in junior high schools (SMP) in Ogan Ilir Regency that receive low evaluation scores in their educational units. The community service partners consist of 11 junior high schools, represented by the Principals and one Vice Principal in charge of curriculum. The implementation method includes three main stages: 1) Training, 2) Mentoring, and 3) Supervision. The evaluation instruments used include questionnaires, observation sheets, and analysis of participants' work documents to measure improvements in knowledge, skills, and attitudes related to literacy and numeracy. Data analysis techniques involve descriptive quantitative and qualitative approaches. The results of this community service activity indicate that partner schools have shown increased knowledge and experience in enhancing professional literacy and numeracy competencies, as well as skills in developing literacy- and numeracy-based learning tools relevant to junior high school students.
Edukasi Seksual & Konseling Remaja untuk Pencegahan Pernikahan Dini di Klinik Bumi Sehat Desa Batu Mekar Kabupaten Lombok Barat
Authors: Isviyanti Isviyanti , Triandini I Gusti Agung Ayu Hari , Hairani Hairani , Gumangsari Ni Made Gita , Hidayati Diana , Kandisa Amelia , Mayasari Astri , Gustiya Sherly Dwi , Astuti Ni Luh Budi
Published: February 2025

This community service activity aims to provide sexual education and prevent early marriage to teenagers using a holistic psychological counseling and parenting approach, from a legal, social, and midwifery perspective. The method of implementing this service used counseling and mentoring on sexual and reproductive health education using a question-and-answer design. The targets of this activity were teenagers from Batu Mekar Village, West Lombok Regency who were still of school age using a questionnaire instrument which was then statistically analyzed using the t test. The results of this service showed that teenagers were aware of the impact of early marriage and understood anemia, and sexual reproductive health about the incidence of early marriage and stunting. By implementing this community service program, a youth posyandu/youth class was successfully established at the Bumi Sehat Clinic. This is useful in providing a forum for teenagers to discuss and consult regarding sexual, physical, and mental reproductive health issues as well as positive activities to prevent early marriage.
UEQ-BASED EVALUATION OF USER EXPERIENCE: A CASE STUDY ON ENGLISH READING WEBSITES DEVELOPMENT
Authors: Wibowo Argo , Lemmuela Alvita Kurniawati  , Susanti Malasari  , Paulina Besty Fortinasari
Published: February 2025

Technology has become essential in education, requiring specialized instructional media tailored to each subject. This study develops a web-based learning system designed specifically for English education, integrating both passive and interactive learning approaches to enhance engagement and effectiveness. This study contributes to showing that passive-interactive English learning websites can help users in both the advanced and non-advanced categories. However, before the system is publicly accessible, system testing focusing on user experience is important to achieve the intended learning objectives. The current study employed the User Experience Questionnaire (UEQ) framework, consisting of 26 questions across the categories of Attractiveness, Pragmatic, and Hedonic. The UEQ framework has been well-validated and widely used in various studies and professional industries for assessing user experience, ensuring that the user experience scores are objective. The findings showed that the system scored lowest in the “Hedonic” category due to a low “Novelty” score of 1.344, which was 31% lower than the highest score “Attractiveness” at 1.962. Interface that visually appealing and offers fresh, dynamic content, users are more likely to stay engaged.  However, the overall average score across the three UEQ categories for the English learning system was 1.823, indicating a good user experience.
Whipple’s Disease, One of Medicine’s Great Imitators: A Case Report
Authors: Heard Francesca , Hart Elizabeth , Fleming Vicki , Santos Claudia , Thomson Ross
Published: February 2025

The authors describe a rare case of a 46-year-old woman, presenting with a 1-year history of a wasting disease and widespread mediastinal lymphadenopathy on imaging. The patient had a history of pulmonary hypertension diagnosed 7 years prior and had been treated with macitentan (an endothelin receptor antagonist) and sildenafil. Following an admission to the authors’ centre with severe anaemia and workup for suspected haematological malignancy, duodenal biopsy confirmed the diagnosis of Whipple’s disease. Interestingly, the patient did not report the cardinal symptoms of arthralgia, fevers, or gastrointestinal upset, emphasising the importance of investigating for Whipple’s disease even in the absence of these symptoms, particularly in the context of malabsorption or chronic wasting disease. Whipple’s disease can be regarded as a ‘great imitator’, often with non-specific signs and symptoms, which can present a diagnostic challenge. Following diagnosis, appropriate antibiotic therapy was commenced, and the patient made a complete clinical recovery, including resolution of pulmonary arterial hypertension, which likely was the presenting feature of this case of Whipple’s Disease, a rare phenomenon associated with this infection.
The Universe with its Systems is Stable
Authors: Annamalai Chinnaraji
Published: February 2025

The distance between any two consecutive systems in the universe remains unchanged in any direction; otherwise, the systems can collide with each other over the period of time.
Reducing Food Wastage in the Agricultural Supply Chain.
Authors: Samaddar Tanuj
Published: February 2025

On-farm food loss and wastage accounts for 16% of the net agricultural related greenhouse gas emissions worldwide & reduction in these emissions have the potential to make a substantial impact on climate change. There is an array of research being undertaken in this area across different countries, food supply chains and multiple stakeholders. This narrative research paper highlights the pressing issues resulting in food loss and wastage along the agricultural supply chain & provides a critical overview of the current research landscape of on-farm and post harvest food loss and waste. It delves into the underlying causes of food wastage such as overproduction triggered by various determinants by fluctuating market demands and prices, changing consumer preferences and economic pressure. In this paper, special focus has been given on proposing potential solutions, some of which have been implemented in different agro-centric economies to reap positive benefits. It emphasizes the importance of improving on farm practices, particularly in developing where rather rudimentary & harsh climatic conditions lead to significant losses of perishable goods. The implementation of cutting edge and advanced technologies such as precision agriculture, ICT, historical data based crop yield prediction, digital agriculture among a plethora of other technologies has been discussed as a means to enhance monitoring and control throughout the food supply chain. This research also investigates the potential solutions including but not limited to anti-ethylene bags, solar dryers, specialized cold storage with thermal energy backup .
The role of m6A modification during macrophage metabolic reprogramming in human diseases and animal models
Authors: Wang Huiling , Xu Peiqi , Yin Kai , Wang Shengjun
Published: February 2025

Macrophage metabolic reprogramming refers to the process by which macrophages adjust their physiological pathways to meet survival and functional demands in different immune microenvironments. This involves a range of metabolic pathways, including glycolysis, the tricarboxylic acid cycle, oxidative phosphorylation, fatty acid oxidation, and cholesterol transport. By modulating the expression and activity of key enzymes and molecules within these pathways, macrophages can make the transition between pro- and anti-inflammatory phenotypes, thereby linking metabolic reprogramming to inflammatory responses and the progression of several diseases, such as atherosclerosis, inflammatory bowel disease (IBD), and acute lung injury (ALI). N6-methyladenosine (m6A) modification has emerged as a critical regulatory mechanism during macrophage metabolic reprogramming, broadly affecting RNA stability, translation, and degradation. Therapeutic strategies targeting m6A modification can regulate the onset of metabolic diseases by influencing macrophage metabolic changes, for instance, small molecule inhibitors of methyltransferase-like 3 (METTL3) can affect glucose metabolism and inhibit IBD. This review systematically explores recent findings on the role and molecular mechanisms of m6A modification during macrophage metabolic reprogramming in human diseases and animal models, underscoring its potential as a therapeutic target for metabolic diseases.
The influence of amniotic membrane proteins on corneal regeneration when delivered directly or using hydrogel platforms
Authors: Basasoro Ayla , Mendicute Javier , Rezola Marta , Burgos Jorge , Fernández Mercedes , Esporrín-Ubieto David , Sonzogni Ana , Calderón Marcelo , Calafel Itxaso , Díaz Aitor , De Souza Juliana , Aiastui Ana , Azkargorta Mikel , Elortza Félix , Vecino Elena , Acera Arantxa
Published: February 2025

Background/aims

Chemical burns to the eye cause extensive ocular surface damage, often resulting in permanent visual impairment. The amniotic membrane (AM), with its regenerative properties, has shown great potential in treating such injuries. Recent innovations, including hydrogel-based delivery systems, have been developed to improve drug retention and promote corneal healing. This study aimed to evaluate whether hydrogels loaded with proteins from human AM could enhance corneal wound healing effectively.

Methods

Alkaline burns (8 mm diameter) were induced in the cornea of anesthetized male New Zealand White rabbits (n = 44) by placing filter paper soaked in 1M NaOH on them for 60 s. After rinsed the corneas immediately with a balanced salt solution, the wounds then received: (1) no treatment; (2) AM transplantation; or (3) a dynamic hyaluronic acid hydrogel based on gold thiolate loaded with an AM protein extract (AME); or (4) a physically cross-linked ocular hydrogel insert loaded with the same AME. The contralateral uninjured eye served as a control. The wound area and proportion of healed corneas was assessed in microphotographs. In addition, corneal histology was evaluated by hematoxylin–eosin and Masson’s trichrome staining, examining epithelial and stromal thickness, the endothelial layer, and inflammatory infiltration in the early (day 2) and late (day 28) phases of healing.

Results

There was more frequent corneal wound closure in animals treated with the hydrogels (treatments 3 and 4) on day 14 (44.4 and 55.5%, respectively) than in the untreated controls (33.3%). Histologically, abnormal re-epithelialization and altered epithelial junctions were observed, with no significant differences in epithelial thickness. Endothelial damage correlated with significant thinning (p = 0.001), with treatments 2 and 3 producing significant differences in the inflammatory infiltrate (p = 0.01).

Conclusion

Applying new biocompatible hydrogels to the ocular surface that release AM proteins may help close corneal wounds caused by caustic burns. The aggressive nature of burns hinders the detection of differences in the wound area between treatments 28 days after injury. However, improving the adhesion of a solid hydrogel to the mucosa of the ocular surface could enhance these outcomes by keeping the implant in contact with the wound for a longer period.
Flexibility, Resistance, Aerobic, Movement Execution (FRAME) training program to improve gait capacity in adults with Hereditary Spastic Paraplegia: protocol for a single-cohort feasibility trial
Authors: Boccuni Leonardo , Bortolini Marco , Stefan Cristina , Dal Molin Valentina , Dalla Valle Giacomo , Martinuzzi Andrea
Published: February 2025

Background

Hereditary Spastic Paraplegia (HSP) is a heterogeneous group of inherited neurological disorders characterized by progressive weakness and spasticity in the lower limbs, significantly affecting gait capacity (endurance and speed). Although specific interventions have been already investigated, there is currently a lack of comprehensive, structured neurorehabilitation programs to improve gait capacity in adults with HSP. Thus, this protocol aims to explore the feasibility and effectiveness of a composite training targeting flexibility, muscle strength, motor control, balance, and aerobic capacity.

Methods

20 adults diagnosed with HSP will participate in 10 to 16 therapist-guided sessions (intervention), lasting 60 to 120 minutes each, occurring once or twice weekly based on individual preferences. Depending on the number and frequency of sessions, the intervention period may vary in between five to 10 weeks. Upon completion, participants will receive a transfer package (manual, video tutorials) to stimulate long-term exercise at home. Assessments will take place before intervention (T0), at the end of the intervention (T1), and 12 weeks post-T1 (T2). Primary outcomes will focus on feasibility (recruitment, retention, adherence, absence of adverse events, and patient's satisfaction). Secondary outcomes will evaluate improvements in gait capacity and specific contributing factors such as reduced spasticity, increased muscle strength, and improved balance.

Relevance

The significance of this protocol is to provide valuable insights for clinicians regarding the feasibility and potential efficacy of a comprehensive, clinical-oriented program to improve gait capacity in adults with HSP, and inform future translational research studies in the field.

Clinical trial registration

ClinicalTrials.gov, identifier NCT06742697.
Effect of Generative Artificial Intelligence on Strategic Decision-Making in Entrepreneurial Business Initiatives: A Systematic Literature Review
Authors: López-Solís Oscar , Luzuriaga-Jaramillo Alberto , Bedoya-Jara Mayra , Naranjo-Santamaría Joselito , Bonilla-Jurado Diego , Acosta-Vargas Patricia
Published: February 2025

Generative Artificial Intelligence (GAI) is emerging as a promising tool with which to improve strategic decision-making in a business environment characterized by increasing complexity. There are external and internal factors that are part of the success of entrepreneurial initiatives. Relevant factors that make decision-making effective include the technological environment, as an external factor, and innovation, as an internal factor. Methods: This study reviews the existing literature on implementing GAI in business decision-making. It assesses its short-, medium- and long-term effects, considering the interaction between GAI and human judgment. Challenges related to uncertainty, complexity, and ambiguity are examined, and the relevant literature is reviewed to understand these aspects comprehensively. Results: The review shows that, despite the advanced capabilities of GAI to analyze data and generate patterns, human judgment remains crucial in situations of high uncertainty. The results suggest that combining GAI with human expertise can improve the accuracy and efficiency of strategic decision-making by integrating the strengths of both parties. Conclusions: The implementation of GAI can offer significant improvements in the efficiency and accuracy of business decisions. However, human judgment and experience remain essential, especially in uncertain contexts. The key to maximizing the benefits of GAI lies in finding the right balance between artificial intelligence and human capital.
Effects of Land Use Changes on CO2 Emission Dynamics in the Amazon
Authors: Rocha Adriano Maltezo da , Franceschi Mauricio , Panosso Alan Rodrigo , Carvalho Marco Antonio Camillo de , Moitinho Mara Regina , Martins Filho Marcílio Vieira , Oliveira Dener Marcio da Silva , Freitas Diego Antonio França de , Yamashita Oscar Mitsuo , La Scala Newton
Published: February 2025

Global climate change is closely tied to CO2 emissions, and implementing conservation-agricultural systems can help mitigate emissions in the Amazon. By maintaining forest cover and integrating sustainable agricultural practices in pasture, these systems help mitigate climate change and preserve the carbon stocks in Amazon forest soils. In addition, these systems improve soil health, microclimate regulation, and promote sustainable agricultural practices in the Amazon region. This study aimed to evaluate the CO2 emission dynamics and its relationship with soil attributes under different uses in the Amazon. The experiment consisted of four treatments (Degraded Pasture—DP; Managed Pasture—MP; Native Forest—NF; and Livestock Forest Integration—LF), with 25 replications. Soil CO2 emission (FCO2), soil temperature, and soil moisture were evaluated over a period of 114 days, and the chemical, physical, and biological attributes of the soil were measured at the end of this period. The mean FCO2 reached values of 4.44, 3.88, 3.80, and 3.14 µmol m−2 s−1 in DP, MP, NF, and LF, respectively. In addition to the direct relationship between soil CO2 emissions and soil temperature for all land uses, soil bulk density indirectly influenced emissions in NF. The amount of humic acid induced the highest emission in DP. Soil organic carbon and carbon stock were higher in MP and LF. These values demonstrate that FCO2 was influenced by the Amazon land uses and highlight LF as a low CO2 emission system with a higher potential for carbon stock in the soil.