bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-regulated learning strategies and academic achievement in South Korean 6th-graders: A two-level hierarchical linear modeling analysis
Authors: Ha Cheyeon , Roehrig Alysia D. , Zhang Qian
Published: April 2023

The aim of the study was to explain the relationships between self-regulated learning strategy use and academic achievement of 6th-grade students in South Korea. An existing database (i.e., the Korean Educational Longitudinal Study; KELS) with 6th-grade students (n = 7,065) from 446 schools was used to run a series of 2-level hierarchical linear models (HLM). This large dataset enabled us to consider how the relationship between learners’ self-regulated learning strategy use and academic achievement may differ at individual and school levels. We found that students’ metacognition and effort regulation positively predicted their literacy and math achievement both within and across schools. The average literacy and math achievement were significantly higher in private schools than in public schools. Also, the math achievement of urban schools was significantly higher than in non-urban schools when controlling other cognitive and behavioral learning strategies. This study on 6th-grade learners’ self-regulated learning (SRL) on academic achievement explores how their SRL strategies may be different from the features of successful adult learners from the previous findings, offering new insights into the development of SRL in elementary education.
COVID-19 pandemic: Impact on the cardiac implantable electronic devices’ implantation rates in Croatia
Authors: Zeljkovic Ivan , Ferri Jerko , Mioc Pavao , Brusich Sandro , Matasic Richard , Jurisic Zrinka , Szavits Nossan Janko , Maricic Lana , Cvitkusic Lukenda Katica , Radeljic Vjekoslav , Pavlovic Nikola , Manola Sime
Published: April 2023

Introduction

Coronavirus disease 2019 (COVID-19) pandemic has influenced health-care organization worldwide, including management of non-communicable diseases. The aim of this study was to determine the impact of COVID-19 pandemic on cardiac implantable electronic devices’ (CIEDs) implantation rates in Croatia.

Methods

A retrospective, observational, national study was conducted. The data on CIEDs’ implantation rates from 20 Croatian implantation centres, between January 2018 and June 2021, were extracted from the national Health Insurance Fund registry. Implantation rates before and after COVID-19 pandemic started, were compared.

Results

The overall numbers of CIED implantations in Croatia during COVID-19 pandemic were not different in comparison to 2 years pre-COVID-19 time (2618 vs. 2807, p = .081). The pacemaker implantation rates decreased significantly (by 45%) during April (122 vs. 223, p < .001) and May 2020 (135 vs. 244, p = .001), as well as during November 2020 (177 vs. 264, p = .003), but significantly increased during summer months 2020 comparing to 2018 and 2019 (737 vs. 497, p<0.001). The ICD implantation rates decreased significantly by 59% in April 2020 (26 vs. 64, p = .048).

Conclusion

To the authors best knowledge this is a first study including complete national data on CIED implantation rates and COVID-19 pandemic impact. A significant reduction in number of both pacemaker and ICD implants during specific months of the COVID-19 pandemic was determined. However, afterwards compensation in implants resulted in similar total number when the complete year was evaluated.
Twitter mobility dynamics during the COVID-19 pandemic: A case study of London
Authors: Zhong Chen , Morphet Robin , Yoshida Mitsuo
Published: April 2023

The current COVID-19 pandemic has profoundly impacted people’s lifestyles and travel behaviours, which may persist post-pandemic. An effective monitoring tool that allows us to track the level of change is vital for controlling viral transmission, predicting travel and activity demand and, in the long term, for economic recovery. In this paper, we propose a set of Twitter mobility indices to explore and visualise changes in people’s travel and activity patterns, demonstrated through a case study of London. We collected over 2.3 million geotagged tweets in the Great London Area (GLA) from Jan 2019 –Feb 2021. From these, we extracted daily trips, origin-destination matrices, and spatial networks. Mobility indices were computed based on these, with the year 2019 as a pre-Covid baseline. We found that in London, (1) People are making fewer but longer trips since March 2020. (2) In 2020, travellers showed comparatively reduced interest in central and sub-central activity locations compared to those in outer areas, whereas, in 2021, there is a sign of a return to the old norm. (3) Contrary to some relevant literature on mobility and virus transmission, we found a poor spatial relationship at the Middle Layer Super Output Area (MSOA) level between reported COVID-19 cases and Twitter mobility. It indicated that daily trips detected from geotweets and their most likely associated social, exercise and commercial activities are not critical causes for disease transmission in London. Aware of the data limitations, we also discuss the representativeness of Twitter mobility by comparing our proposed measures to more established mobility indices. Overall, we conclude that mobility patterns obtained from geo-tweets are valuable for continuously monitoring urban changes at a fine spatiotemporal scale.
A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans
Authors: Probst Corinna , Hallas-Møller Magnus , Ipsen Johan Ø. , Brooks Jacob T. , Andersen Karsten , Haon Mireille , Berrin Jean-Guy , Martens Helle J. , Nichols Connie B. , Johansen Katja S. , Alspaugh J. Andrew
Published: April 2023

Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division. These morphological changes require reorganization of the cell wall, a structural feature external to the cell membrane composed of highly interconnected polysaccharides and glycoproteins. Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that are typically secreted into the extracellular space to catalyze initial oxidative steps in the degradation of complex biopolymers such as chitin and cellulose. However, their roles in modifying endogenous microbial carbohydrates are poorly characterized. The CEL1 gene in the human fungal pathogen Cryptococcus neoformans (Cn) is predicted by sequence homology to encode an LPMO of the AA9 enzyme family. The CEL1 gene is induced by host physiological pH and temperature, and it is primarily localized to the fungal cell wall. Targeted mutation of the CEL1 gene revealed that it is required for the expression of stress response phenotypes, including thermotolerance, cell wall integrity, and efficient cell cycle progression. Accordingly, a cel1Δ deletion mutant was avirulent in two models of C. neoformans infection. Therefore, in contrast to LPMO activity in other microorganisms that primarily targets exogenous polysaccharides, these data suggest that CnCel1 promotes intrinsic fungal cell wall remodeling events required for efficient adaptation to the host environment.
The revival is dead: Is this something else? Or, holding onto Anta Helena Recke’s MITTELREICH as a work of art
Authors: Lord Crispin
Published: April 2023

In 2017, Anta Helena Recke restaged the production of MITTELREICH on which she had previously been employed as the assistant director, with one crucial difference: the entire cast, orchestra and creative team were now Black. This action, which she named a Schwarzkopie (‘black copy’), exposed a raft of material racial inequalities within the European theatre industry and brought about a more abstract inquiry into the very idea of a theatrical copy. In this article I bring some of the material and theoretical consequences of Recke’s production in direct conversation with McKenzie Wark’s thought experiments on finding, after Marx, a new language for the contemporary modes of production. Wark’s insistence on historical materialism provides a helpful framing for uncovering the specific value(s) of Recke’s staging and allows a discussion on class relations to enter a hitherto stymied debate around identity politics in European theatre.
Intersectionality Based Policy Analysis of How Racism is Framed in Medical Education Policies Guiding Aboriginal Health Curriculum
Authors:   Monash University, Atkinson Petah , Baird Marilyn ,   Monash University, Adams Karen ,   Monash University
Published: April 2023

Introduction: Racism has a profound impact on health inequities for Aboriginal and Torres Strait Islander people. Australian medical schools are required to include Aboriginal and Torres Strait Islander health curriculum in their medical courses and policies have been developed to support this work. Methods: The research question was: how is racism framed in medical education policies guiding Aboriginal and Torres Strait Islander health curriculum for entry-level medical courses? Applying an Indigenous Research Paradigm and Intersectionality Based Policy Analysis, three key policies were analysed: Australian Medical Council (AMC) Standards for Assessment and Accreditation of Primary Medical programs; Aboriginal and Torres Strait Islander Health Curriculum Framework (ATSIHCF); Committee of Deans of Australasian Medical Schools Indigenous Health Curriculum Framework (CDAMS). Results: The AMC standards did not refer to racism, while CDAMS and ATSICF supported the notion that teaching students about racism would lead to reduced racism or increased anti-racism in healthcare practice. However, both policies’ learning objectives lacked inclusion of critical reflection required to inform responsive action to racism. As the CDAMS and ATSIHCF were not mandated, there is little accountability for medical schools to implement either of the curriculum policies. Conclusion: Realising the goal of medical practitioners who understand racism and practice anti-racism requires a multi-layered approach. This involves evidence-based teaching about racism and anti-racism, Aboriginal and Torres Strait Islander leadership in curriculum development, inclusion of racism and anti-racism in medical school accreditation standards, and development of student critical reflection skills. Importantly, education and health institutions need to value and model anti-racism.
Brief Report: Out of Sight Out of Mind - Preventable Childhood Kidney Disease in the Far North
Authors:   Torres and Cape Hospital and Health Service, Neville Johanna , Hempenstall Allison ,   James Cook University, Taunton Caroline ,   Torres and Cape Hospital and Health Service, Fisher Valmay ,   Torres and Cape Hospital and Health Service, McDonald Malcolm ,   James Cook University
Published: April 2023

APSGN is an immune-mediated kidney disease that occurs after a Streptococcus pyogenes skin or throat infection in children and contributes to chronic kidney disease later in life. It is a disease of poverty and regrettably common in Aboriginal and Torres Strait Islander children. There have been seven documented APSGN outbreaks across Far North Queensland in the last nine years. Despite this disease being notifiable in both Western Australia and the Northern Territory, Queensland is yet to acknowledge the importance of early notification in the management of APSGN. Notification-driven publication of APSGN incidence should help raise its profile and stimulate better public health policy.
Addressing Environmental Migration in the European Union Discourse
Authors: Wirthová Lucia
Published: April 2023

For decades, the European Union (EU) has been addressing issues related to climate change and ecological degradation as a self-proclaimed pro-environmental and human rights-oriented actor. Correspondingly, the topic of environmentally driven migration entered the EU discourse at the dawn of the new millennium. As such, environmental migrants around the world find themselves in an existential crisis and are in need of support whether it comes to questions of compensations, relocation, protection of cultural heritage etc. Thus, considering the EU’s interest in the human rights and environmental/climate issue areas, I argue it is important to ask what the Union’s approach to this matter has been. Consequently, this article assesses the European Union discourse related to the topic of environmental migration over a twenty-year period. Through the theoretical lens of the Copenhagen School of Security Studies and the normative power EU conception, this paper critically analyzes the EU’s securitization of climate change in relation to environmental migrants who are experiencing an existential threat to their lives. Based on a qualitative discourse analysis, the preliminary results imply that the topic has been receding into the background of the EU agenda. In line, environmental migrants have been pushed aside by a multiplicity of other subjects threatened by climate change, and their problems were thus not reflected in either the EU climate change or migration management policies. Overall, the findings show a shift from an alarmist discourse to pragmatism on the EU’s behalf. Thereupon, this article questions the normative standard the EU sets for itself when it comes to the case of environmental migrant protection.
Crime e Castigo: a economia do crime e as abordagens de aprendizado na psicologia
Authors: Coelho Sigrist Felipe , Regina Marin Solange
Published: April 2023

Este artigo tem como objetivo discutir como a temática do aprendizado, sob uma perspectiva da psicologia, é incorporada aos estudos de Economia do Crime. Inicialmente, é feita uma breve apresentação das duas principais abordagens psicológicas sobre o aprendizado, behaviorista e cognitiva. Na sequência, tratamos do problema do aprendizado dentro da Criminologia e analisamos como outra área do conhecimento, a sociologia, aborda o tema e, posteriormente, revisamos os estudos da Teoria Econômica do Crime que possibilitam aprendizado. Discutimos, então, as limitações que o uso de métodos dedutivos, usualmente utilizados na economia neoclássica, impõem ao estudo do aprendizado no contexto da tomada de decisão criminal.
Formação de Preços em Oligopólio: abordagens heterodoxas sob perspectiva bibliométrica
Authors: De Oliveira Sposito Theodoro Cesar , De Lazari Fonseca Laura Alice
Published: April 2023

Este artigo tem como objetivo mapear a produção acadêmica de viés heterodoxo sobre formação de preços em oligopólio a partir do aparato metodológico da bibliometria. Para tanto, analisou-se uma amostra com 113 artigos publicados entre 1980 e 2021 nos 100 principais periódicos heterodoxos segundo o “Heterodox Journal Quality Score”, de Lee et al. (2010), a partir da qual foram construídas redes bibliométricas de citação, co-citação, co-ocorrência e acoplamento bibliográfico. Entre os resultados, destacou-se dois: (i) a principal corrente heterodoxa neste segmento é a pós-keynesiana; e (ii) as leis bibliométricas de Bradford, Lotka e Zipf são válidas para a amostra.
Visados para soñar: expectativas y emociones de adolescentes y jóvenes que migran solos/as
Authors: Segú Odriozola Mabel , Gómez-Quintero Juan David , Casado Patricio Elena , Aurrekoetxea-Casaus Maite
Published: April 2023

La mayor parte de las investigaciones sobre los/as adolescentes y jóvenes que migran solos/as se focalizan en las causas y condiciones de su viaje migratorio y su asentamiento en las sociedades de destino. Sin embargo, hay pocos trabajos que aborden sus expectativas de futuro y, especialmente, las emociones que suscitan sus proyectos venideros. El objetivo de la investigación es identificar sus expectativas y analizar las emociones que estas provocan. La metodología consiste en el análisis cualitativo de 118 entrevistas realizadas en siete CC. AA. del Estado español a partir de categorías de análisis tales como expectativas de la migración, proyectos de futuro y emociones experimentadas. Los resultados señalan la existencia de tres conjuntos de expectativas: materiales-funcionales, simbólicas-ideales y afectivas-territoriales. Así mismo, el estudio señala que, a pesar de la emergencia de un amplio espectro de emociones, las más recurrentes son el sufrimiento, la incertidumbre y el sentimiento de orgullo por lo que han sido capaces. Este estudio contribuye a ampliar la mirada de las migraciones juveniles desde una perspectiva cualitativa que permite comprender el complejo entramado de sueños, proyectos, miedos y sufrimientos experimentados por adolescentes y jóvenes que han migrado solos/as a España.
“Estampas Limeñas”. Recuperación de la memoria sobre la disidencia sexual en doscientos años de República. Del imaginario social a la imaginación radical
Authors: Álvarez Chávez Roland Jeremy , Jaramillo Huamán Carlos
Published: April 2023

El proyecto “Estampas Limeñas” tienen el objetivo de recuperar la memoria de sujetos de la diversidad sexual. La propuesta se centra en la identificación, recuperación y (re)construcción de las vivencias de dichos sujetos, teniendo como escenario la ciudad de Lima en sus diversos espacios físicos y temporales. El proyecto, que actualmente está en marcha, identifica ciertos pasajes históricos o hitos desde la fundación de la República del Perú (s. XIX) hasta la actualidad (s. XXI). Los diferentes pasajes históricos creados en este proceso son un ensayo de (re)construcción de nuestra realidad frente a una verdad institucionalizada que nos ha invisibilizado, usando para ello la “imaginación radical”, el cual tiene como insumo central el componente intersubjetivo de la “epistemología marica”. Este ejercicio, a partir de evidencia y referentes de material histórico, periodístico, académico e incluso testimonial, autobiográfico y autoficcional instituye una serie de situaciones inspiradas en la posibilidad de proyección de la vivencia y la experiencia individual y colectiva “marica”. El resultado es la recuperación y (re)construcción de lo que consideramos parte de nuestra memoria, verdad e historia, a partir de un proceso de posicionamiento de una voz disidente, ello enmarcado además en la celebración de nuestro bicentenario como país independiente.
Estudios sobre las mujeres afrodescendientes en el Caribe colombiano: una revisión del tema
Authors: Bedoya Gonzalez Yesica Andrea
Published: April 2023

El desarrollo de los estudios afrocolombianos ha ido nutriéndose de diversas disciplinas sociales en Colombia desde finales de la década de los setenta del siglo pasado, dando avances en la consolidación de nuevos campos de investigación de los que se desligan sujetos de estudio que se traducen en historias contadas (y no contadas). Uno de estos sujetos han sido las mujeres que llegaron al continente mediante el comercio de esclavos hacia América, provocando un sinfín de acciones ya fuesen dentro o fuera de las normas de los virreinatos. Es por esto que el objetivo de este artículo es, desde un enfoque cualitativo, evidenciar cuáles han sido las áreas y las temáticas que se han estudiado desde las mujeres afrodescendientes en el Caribe colombiano, brindando un panorama sobre las principales líneas de investigación sobre el tema. Dentro de los resultados se halla que las mujeres han sido estudiadas desde la historia como sujetas activas dentro de cada contexto, desde la organización política a través de los movimientos de mujeres y feministas en el Caribe colombiano, desde las mujeres palenqueras y desde el estudio de sus identidades, prácticas y discursos.
The Risk Factors of Hypertension Among the Elderly in the Working Area of Sikumana Primary Health Care Center
Authors: Dida Grace Youngest , Nayoan Christina Rony , Sir Amelya Betsalonia
Published: April 2023

Introduction: The elderly are prone to hypertension. This study aimed to analyze the risk factors of diet and physical activity for hypertension in the elderly in the working area of Sikumana Primary Health care center in 2022.Method: This analytical observation study was conducted in a case-control design. The subjects were 100 elderly (50 cases and 50 controls). Simple random sampling was used to choose the subjects. Data collection was done by interviews using structured questionnaires. Data analysis was done through the Chi-Square test and Odd Ratios.Results: The results showed that the elderly who has an unhealthy diet were 4.45 times more likely to have hypertension (OR= 4.45, 95% CI: 1.68-11.81; p=0.004). The elderly who had lacked of physical activity were 5.52 times more likely to have hypertension (OR=5.5, 95% CI: 1.86-16.34; p=0.002).Conclusion:  The risk factors for hypertension among the elderly in the working area of Sikumana Primary health care center were unhealthy diet and lack of physical activity. It is suggested that primary health care centers should promote healthy food, salt and fat reduction in the diet and increase physical activities through Posyandu (integrated health post), especially for elderly
Extremal metrics on toric manifolds and homogeneous toric bundles
Authors: Li An-Min , Lian Zhao , Sheng Li
Published: April 2023

In this paper, we prove the Yau–Tian–Donaldson conjecture of the filtration version for toric manifolds and homogeneous toric bundles, thus for toric manifolds and homogeneous toric bundles, M admits an extremal metric in

c
1

⁢

(
L
)

{c_{1}(L)}

if and only if

(
M
,
L
)

{(M,L)}

is relatively

K
^

{\widehat{K}}

-stable.
Mabuchi geometry of big cohomology classes
Authors: Xia Mingchen
Published: April 2023

Let X be a compact Kähler manifold.
Fix a big

(
1
,
1
)

{(1,1)}

-cohomology class α with smooth representative θ.
We study the spaces

ℰ
p

⁢

(
X
,
θ
)

{\mathcal{E}^{p}(X,\theta)}

of finite energy Kähler potentials for each

p
≥
1

{p\geq 1}

.
We define a metric

d
p

{d_{p}}

without using the Finsler geometry nor solving Monge–Ampère-type equations. This construction generalizes the usual

d
p

{d_{p}}

-metric defined for an ample class.
Uncertainty inequality on weighted Hardy spaces
Authors: Soltani Fethi
Published: April 2023

In this paper we introduce a weighted
Hardy space

ℋ
β

{\mathscr{H}_{\beta}}

. This space
generalizes some complex Hilbert spaces like the Dirichlet
space

𝒟

{\mathscr{D}}

, the Bergman space

𝒜

{\mathscr{A}}

and the
Segal–Bargmann space

ℱ

{\mathscr{F}}

. It plays the role of background for our
contribution. In particular, we study the derivative operator D and
its adjoint operator

L
β

{L_{\beta}}

on

ℋ
β

{\mathscr{H}_{\beta}}

.
Furthermore, we establish a general uncertainty inequality of
Heisenberg type for the space

ℋ
β

{\mathscr{H}_{\beta}}

.
Insights into the self-assembly of fampridine hydrochloride: how the choice of the solvent affects the crystallization of a simple salt
Authors: Fusaro Luca , Tumanov Nikolay , Saielli Giacomo , Montis Riccardo
Published: April 2023

Crystalline materials and crystallization processes play an important role in several fields of science, such as pharmaceuticals, material science, pigments, optoelectronics, catalysis and energy storage. Understanding and defining the right conditions of crystallization is therefore crucial. Among the several factors influencing the crystallization of a given compound, the choice of the solvent system is perhaps one of the most important. The nature of solvent–solute interactions can indeed have a role in promoting specific molecular assemblies, therefore affecting crystallisation rates of a crystal and often resulting in the nucleation of different polymorphs and solvates. Here we investigated the role of a binary mixture of solvent (water/acetone) in the crystallisation of a simple salt of 4-aminopyridinium chloride. Previous results on this compound showed that when crystallised from water it forms a simple hydrate structure, while in the presence of acetone, it undergoes a liquid-liquid phase separation, followed by the crystallisation of a complex structure belonging to the Frank–Kasper (FK) phases, a particular family of topologically close-packed structures never observed in small and rigid molecules. To broaden the understanding of how such a simple molecule may crystallise as an FK phase, we carried out the crystallization of the complex phase by antisolvent diffusion (in a mixture of water/acetone) and that of the monohydrate phase in water, monitoring the liquid precursors by liquid-state NMR. In particular, we applied 1H, 13C, 14N, 17O, and 35/37Cl NMR as a function of the concentration of 4APH+Cl− until the moment when precipitation of the crystalline phases occurred. Variations of chemical shifts, T1 relaxation times of 13C signals, and full-width at half-maximum of the signals of quadrupolar nuclei were also measured. The spatial proximity between the different species in the solution was investigated by NOE experiments. In order to support these results, we also performed Molecular Dynamics simulations, investigating the potential solute/solvents interactions. The results strongly suggest that acetone, instead of behaving as an anti-solvent, interacts directly with the solute, preventing the formation of the simple monohydrate structure and, at the same time, promoting specific molecular aggregations.
Circular plastics technologies: pyrolysis of plastics to fuels and chemicals
Authors: Knauer Katrina M. , Higginson Cody , Lee Minjung
Published: April 2023

Pyrolysis technologies are a staple in plastic chemical recycling because of the robustness to contamination and existing infrastructure. Pyrolysis is already considered to be a reasonably mature technology with numerous pilot plants operating to pyrolyze plastic waste into fuels and chemicals. This chapter will describe the pyrolysis process and important process parameters, the types of plastics that are suitable for pyrolysis recycling, the mechanism of pyrolytic degradation of various plastics, the products derived from different plastics, companies that have successfully scaled pyrolysis recycling, and recent innovations in the technology.
EDUCAÇÃO PARA AS MULHERES
Authors: Oliveira Verona Stéfani
Published: April 2023

Este trabalho tem como tema a educação feminina nos Estados Unidos, com a finalidade de entender as transformações sociais posteriores à Revolução Americana que tornaram possível a disseminação das academias femininas. O recorte faz parte de uma pesquisa de mestrado e tem como objetivo entender o cenário de mudanças no país após as Guerras de Independência para entender a adaptação no discurso com relação à mulher, que a encaixou em um papel republicano específico após a “descolonização”. Parto desta perspectiva para entender a formação das primeiras academias femininas durante o início do século XIX através de duas abordagens amplamente discutidas na época: por um lado como forma de questionar as ideias de igualdade e autonomia da Revolução Americana e, por outro, como forma de desenvolver uma educação “adequada” às mulheres republicanas virtuosas, que, segundo os homens, exerciam papel seu cívico sendo as educadoras de seus filhos. A metodologia utilizada é a revisão bibliográfica de autores que tratam da educação nos Estados Unidos e a convergência com os Estudos de Gênero, partindo principalmente da ideia de “representação social”. Percebo que nos Estados Unidos as práticas de escrita e leitura e os ideais da independência transformaram o cenário da educação das mulheres, ainda que o maior acesso à educação estivesse primordialmente ligado à sua preparação para exercer certo papel social. O sucesso das academias serviu para atestar a capacidade racional das mulheres e foi através destes espaços que mais delas começaram a questionar sua dependência dos homens.
ENTREVISTA A JULIA MELGARES
Authors: Sebasti Sabina , Caetano Marcio
Published: April 2023

Nas regiões de fronteira as relações sociais se estabelecem na dinâmica dos fluxos migratórios, atravessadas pela condição de configurar uma demarcação geopolítica entre dois Estados, caracterizadas pelas inter-relações entre cidadãos, migrantes, estrangeiros, radicados ou em trânsito, que permanentemente integram as populações sobre uma ou outra margem. Tal como acontece em outras regiões fronteiriças sul-americanas, na área que abrange às cidades limítrofes de Río Branco (Uruguay) e Jaguarão (Brasil), área foco deste estudo, as mulheres desenvolvem estratégias de sobrevivência que implicam cruzar o território em forma frequente. Uma parte significativa da população feminina se converte em transfronteiriça, opta pela birresidencialidade ou binacionalidade. O presente artigo pretende iniciar uma linha de investigação e discussão sobre as condições de vida das mulheres em uma região destas características. O método utilizado foi uma entrevista em profundidade realizada, em setembro de 2021, a Julia Melgares, política, ativista social e vereadora. As respostas concedidas pela entrevistada resultaram reveladoras da conjuntura social e econômica que define à condição da mulher nesta região de fronteira. Na biografia e na voz de Julia foi possível analisar como as habilidades das mulheres, para estabelecer vínculos relacionais, repercutiam nas suas situações de vida em uma região com escasso desenvolvimento humano, afetada pela falta de acesso aos serviços básicos do Estado, assim como também conhecer os desafios políticos da luta feminista local e como se articulam nas ações das organizações e movimentos sociais.
O EFEITO DA AUSÊNCIA DE DISCUSSÕES SOBRE GÊNERO E SEXUALIDADES NA ESCOLA
Authors: Pereira dos Santos Luciano , Alves Lagôa Júnior José
Published: April 2023

Este trabalho tem como pretensão a reflexão sobre a ausência de discussões sobre gênero e sexualidades na escola e seus efeitos na produção e manutenção da LGBTfobia no ambiente escolar, tendo como foco as percepções de estudantes da EJA de uma escola pública de Pelotas/ RS. Os dados foram produzidos por meio da aplicação de questionários e a análise pautou-se na análise temática de conteúdo.  Os resultados apontam desconhecimentos sobre o assunto e detecta a forte presença da LGBTfobia no espaço escolar. Destaca-se que tais resultados foram aferidos em período anterior a pandemia de COVID-19. A população LGBTQIA+ é um dos grupos mais afetados pelo período pandêmico onde pode ser observado aumento no índice de violência contra as sexualidades dissidentes, cerceamento do acesso à atendimento de saúde, desemprego, insegurança alimentar, dentre outros. Conclui-se que o agravamento da rejeição à diversidade sexual no ambiente escolar é um dos efeitos da ausência de discussões sobre essas temáticas na grade curricular. Defende-se que é de fundamental importância a inserção das temáticas de gênero e sexualidades na grade curricular da formação inicial docente e cursos de formação continuada que promovam inclusão, entendimento e respeito às diferentes identidades sexuais e de gênero na escola.
COMUNIDADE LGBTQIA+ E AS CONDIÇÕES DE ACESSO E PERMANÊNCIA NO ENSINO SUPERIOR
Authors: Simões Rebouças Willame Anderson , Da Costa Marinho Iasmin , Rafaelly Cosme da Silva Yatamuri
Published: April 2023

Considerando os escandalosos números de mortes de indivíduos pertencentes à comunidade LGBTQIA+, fruto da discriminação e do preconceito que ceifam o direito à vida desses indivíduos, o artigo em tela tem como objetivo refletir sobre as condições de acesso e permanência da comunidade LGBTQIA+ ao ensino superior. Para tanto, o estudo contou com as contribuições teóricas de Jesus, Souza e Silva[1], Souza[2]; Acosta[3]; Vieira Junior[4] e entre outros. Enquanto percurso metodológico, a pesquisa é de abordagem qualitativa e combina estratégias de levantamento e análise de produções científicas recolhidas junto às bases de dados Scientific Electronic Library Online (SCieLo); e Google Acadêmico, no período de 2007 a 2021. Resulta da análise o entendimento que, para a comunidade LGBTQIA+, as condições de acesso e permanência no ensino superior são reflexos de um contexto histórico de privação e exclusão ainda vividos na educação básica, dificultando os percursos formativos e de vida dessa comunidade. A perpetuação da lógica capitalista, patriarcal, racista e sexista da sociedade, revela contornos cruéis quanto à sobrevivência e dignidade humana dos indivíduos que assumem identidades divergentes da cisheteronormatividade. Assim, faz-se necessário pensar políticas públicas que ampliem as possibilidades de acesso e permanência desses sujeitos nas universidades, mas também, que os espaços de ensino produzam uma sociabilidade inclusiva, assumindo uma concepção de educação integral e sem reforço de diferenças. Tal proposição não se dará de forma imediata, e requer vontade política de todos àqueles que fazem a escola, a universidade e os sistemas públicos e privados de ensino no Brasil.
VISIBILIDADE LBT+ E RESISTÊNCIA ENTRE QUADRINISTAS BRASILEIRAS
Authors: Tavares Chico Márcia
Published: April 2023

O presente trabalho tem por objetivo analisar obras selecionadas de quadrinistas brasileiras mulheres para avaliar como seus quadrinhos são utilizados para dar visibilidade à população LBT+. Para tal, procurou-se no banco de dados BAMQ! do site Lady’s Comics quadrinistas cuja obra estivesse disponível online. Após a escolha das quadrinistas, selecionaram-se obras de cada uma delas cuja temática girasse em torno da realidade LBT+ ou que apresentasse elementos da mesma. A seguir, analisaram-se as obras selecionadas levando em conta dados teóricos de gênero e sexualidade, como Butler[1]. As obras analisadas apresentam personagens LBT+ existindo em sociedade e realizando atividades corriqueiras, como ir ao bar, ou atividades consideradas normais em nossa sociedade, como a maternidade. Assim, pode-se ver que a própria existência de personagens LBT+ em locais públicos e a performance de atividades cotidianas são consideradas formas de resistência e como a população LBT+ precisa enfrentar obstáculos para simplesmente existir e realizar tarefas consideradas comuns.
NO FUNDO DE UM POÇO VAZIO
Authors: Lana Novais Mario Augusto , Pereira Ourique João Luis
Published: April 2023

Esse trabalho foi realizado no âmbito do Projeto de Pesquisa Amores Expressos: Identidades Ocultas (UFPel). Na investigação do projeto, elenca-se algumas representações de identidades às margens e/ou fragmentadas, na literatura contemporânea, restringindo-se às personagens produzidas no projeto literário Amores Expressos, idealizado pela Companhia das Letras em 2007. Uma dessas personagens é Cleo, uma mulher trans, protagonista do romance de Terron, Do Fundo Do poço se Vê a Lua[1], objeto analítico desse artigo. Para a análise dela considerou-se perspectivas formuladas a partir da teoria da Literatura e Crítica Social. É importante, ainda, uma abordagem a partir da Teoria Queer. Foi realizada, portanto, uma revisão bibliográfica iniciada a partir da obra de David Willian Foster. Compreende-se aqui que a Teoria Queer foi a vertente mais viável para atingir o objetivo dessa produção, que é a construção de uma reflexão sobre a condição de solidão da personagem Cleo. Durante essa análise, entende-se que a personagem é atravessada pelas estruturas do machismo e da transfobia, braços fortes do patriarcado no controle dos corpos. Cleo acaba, invariavelmente, empreendendo em uma busca solitária por sua identidade. Imersa em sua fragmentação, suas escolhas acabam levando-a para descaminhos entre a “fama” e o abuso de seu corpo no submundo da dança do ventre, na Cidade do Cairo, local onde é violentada e morta por mãos dos homens. Essa Análise se encaminha, ainda, à possibilidade de se traçar uma comparação interartística. Conclui-se que Terron tece em sua obra um enredo que se aproxima de paradigmas de representação arraigados nos conceitos da década de 80. Ao se realizar o confronto dessa obra com produções mais recentes, no contemporâneo, percebe-se mudanças nos paradigmas de representação de personagens LGBTQIA+ em nossa cultura.
NMDA Receptors at Primary Afferent–Excitatory Neuron Synapses Differentially Sustain Chemotherapy- and Nerve Trauma-Induced Chronic Pain
Authors: Huang Yuying , Chen Hong , Jin Daozhong , Chen Shao-Rui , Pan Hui-Lin
Published: April 2023

The spinal dorsal horn contains vesicular glutamate transporter-2 (VGluT2)-expressing excitatory neurons and vesicular GABA transporter (VGAT)-expressing inhibitory neurons, which normally have different roles in nociceptive transmission. Spinal glutamate NMDAR hyperactivity is a crucial mechanism of chronic neuropathic pain. However, it is unclear how NMDARs regulate primary afferent input to spinal excitatory and inhibitory neurons in neuropathic pain. Also, the functional significance of presynaptic NMDARs in neuropathic pain has not been defined explicitly. Here we showed that paclitaxel treatment or spared nerve injury (SNI) similarly increased the NMDAR-mediated mEPSC frequency and dorsal root-evoked EPSCs in VGluT2 dorsal horn neurons in male and female mice. By contrast, neither paclitaxel nor SNI had any effect on mEPSCs or evoked EPSCs in VGAT neurons. In mice with conditionalGrin1(gene encoding GluN1) KO in primary sensory neurons (Grin1-cKO), paclitaxel treatment failed to induce pain hypersensitivity. Unexpectedly, SNI still caused long-lasting pain hypersensitivity inGrin1-cKO mice. SNI increased the amplitude of puff NMDA currents in VGluT2 neurons and caused similar depolarizing shifts in GABA reversal potentials in WT andGrin1-cKO mice. Concordantly, spinalGrin1knockdown diminished SNI-induced pain hypersensitivity. Thus, presynaptic NMDARs preferentially amplify primary afferent input to spinal excitatory neurons in neuropathic pain. Although presynaptic NMDARs are required for chemotherapy-induced pain hypersensitivity, postsynaptic NMDARs in spinal excitatory neurons play a dominant role in traumatic nerve injury-induced chronic pain. Our findings reveal the divergent synaptic connectivity and functional significance of spinal presynaptic and postsynaptic NMDARs in regulating cell type-specific nociceptive input in neuropathic pain with different etiologies.

SIGNIFICANCE STATEMENTSpinal excitatory neurons relay input from nociceptors, whereas inhibitory neurons repress spinal nociceptive transmission. Chronic nerve pain is associated with aberrant NMDAR activity in the spinal dorsal horn. This study demonstrates, for the first time, that chemotherapy and traumatic nerve injury preferentially enhance the NMDAR activity at primary afferent–excitatory neuron synapses but have no effect on primary afferent input to spinal inhibitory neurons. NMDARs in primary sensory neurons are essential for chemotherapy-induced chronic pain, whereas nerve trauma causes pain hypersensitivity predominantly via postsynaptic NMDARs in spinal excitatory neurons. Thus, presynaptic and postsynaptic NMDARs at primary afferent–excitatory neuron synapses are differentially engaged in chemotherapy- and nerve injury-induced chronic pain and could be targeted respectively for treating these painful conditions.
Radical Women and Digital Bodies
Authors: Fernández María
Published: April 2023

This Dialogues takes the 2017–18 exhibition Radical Women: Latin American Art, 1960–1985 as a starting point to discuss Latin American art today, addressing its history, legacy, and contribution to positive social change through the prism of feminism. Seeking to challenge hegemonic readings of the categories of “Latin America” and “feminism” while reinstating the contribution of Latin American women, Latina/Latinx, and Chicana/Chicanx artists to art and critical thought today, the exhibition Radical Women proposed novel ways of displaying art from the region by embracing multiplicity, attending to the particularity of different contexts, and bringing to the fore common threads of critical and creative practice. Building on that premise, these contributions expand on the original exhibition’s time frame and consider the persistence of feminism and its changing status in Latin American art after 1985. They explore recent artistic practices, curatorial projects, and art historical scholarship; reflect on strategies of display, audience engagement, societal concerns, and epistemological premises; and consider different ways of conceptualizing Latin American and feminist identities, legacies, and genealogies today. By doing so, this Dialogues seeks to enrich and diversify our understanding of past and current practices, as well as highlight the intricate connections and resonances that exist between the two. Contributions by curators (Fajardo-Hill, Rjeille), scholars (Fernández, Lamoni), and artists (Antivilo, Motta) span issues in political activism, ecology, technology, education, genealogy, colonization, heritage, and memory. What emerges is a sense of the field’s present concerns and the ways this is shaping the future direction of feminism in Latin American art and art history.
Water Is a Time Machine
Authors: Motta Aline
Published: April 2023

This Dialogues takes the 2017–18 exhibition Radical Women: Latin American Art, 1960–1985 as a starting point to discuss Latin American art today, addressing its history, legacy, and contribution to positive social change through the prism of feminism. Seeking to challenge hegemonic readings of the categories of “Latin America” and “feminism” while reinstating the contribution of Latin American women, Latina/Latinx, and Chicana/Chicanx artists to art and critical thought today, the exhibition Radical Women proposed novel ways of displaying art from the region by embracing multiplicity, attending to the particularity of different contexts, and bringing to the fore common threads of critical and creative practice. Building on that premise, these contributions expand on the original exhibition’s time frame and consider the persistence of feminism and its changing status in Latin American art after 1985. They explore recent artistic practices, curatorial projects, and art historical scholarship; reflect on strategies of display, audience engagement, societal concerns, and epistemological premises; and consider different ways of conceptualizing Latin American and feminist identities, legacies, and genealogies today. By doing so, this Dialogues seeks to enrich and diversify our understanding of past and current practices, as well as highlight the intricate connections and resonances that exist between the two. Contributions by curators (Fajardo-Hill, Rjeille), scholars (Fernández, Lamoni), and artists (Antivilo, Motta) span issues in political activism, ecology, technology, education, genealogy, colonization, heritage, and memory. What emerges is a sense of the field’s present concerns and the ways this is shaping the future direction of feminism in Latin American art and art history.
DOT1L regulates chromatin reorganization and gene expression during sperm differentiation
Authors: Blanco Mélina , El Khattabi Laila , Gobé Clara , Crespo Marion , Coulée Manon , de la Iglesia Alberto , Ialy‐Radio Côme , Lapoujade Clementine , Givelet Maëlle , Delessard Marion , Seller‐Corona Ivan , Yamaguchi Kosuke , Vernet Nadège , Van Leeuwen Fred , Lermine Alban , Okada Yuki , Daveau Romain , Oliva Rafael , Fouchet Pierre , Ziyyat Ahmed , Pflieger Delphine , Cocquet Julie
Published: April 2023

Spermatozoa have a unique genome organization. Their chromatin is almost completely devoid of histones and is formed instead of protamines, which confer a high level of compaction and preserve paternal genome integrity until fertilization. Histone‐to‐protamine transition takes place in spermatids and is indispensable for the production of functional sperm. Here, we show that the H3K79‐methyltransferase DOT1L controls spermatid chromatin remodeling and subsequent reorganization and compaction of the spermatozoon genome. Using a mouse model in which Dot1l is knocked‐out (KO) in postnatal male germ cells, we found that Dot1l‐KO sperm chromatin is less compact and has an abnormal content, characterized by the presence of transition proteins, immature protamine 2 forms and a higher level of histones. Proteomic and transcriptomic analyses performed on spermatids reveal that Dot1l‐KO modifies the chromatin prior to histone removal and leads to the deregulation of genes involved in flagellum formation and apoptosis during spermatid differentiation. As a consequence of these chromatin and gene expression defects, Dot1l‐KO spermatozoa have less compact heads and are less motile, which results in impaired fertility.
Óbitos decorrentes de intoxicação oral por cianeto – análise de 13 casos e dos riscos ocupacionais envolvidos
Authors: Bordoni Leonardo Santos , Do Couto Tauer Jordani Gusmão , Do Carmo Sumaia Alves Moura Chaves , Bordoni Polyanna Helena Coelho
Published: April 2023

O cianeto, uma toxina mitocondrial, é considerado uma das substâncias mais letais com as quais podemos ter contato. Há diversos compostos de cianeto, sendo mais frequentes sais de sódio ou potássio, gás cianídrico ou glicosídeos cianogênicos em plantas. A maioria das intoxicações é por via oral, sendo grande desafio diagnóstico em unidades de atendimento médico e na investigação forense dos óbitos. O manejo de cadáveres intoxicados por cianeto apresenta risco ocupacional pela potencial exposição a gases proveniente do corpo. Considerando a escassez de dados nacionais sobre este tema, foi realizado estudo com 13 laudos de necropsias de intoxicações orais por cianeto do Laboratório de Toxicologia do Instituto Médico Legal André Roquette, no período de 2002 a 2018. Em sete casos foi sugerida a suspeita de suicídio, sendo o restante classificado como morte “a esclarecer”. A maioria eram homens (84,6%), brancos (76,9%) e a idade média foi de 41,8 anos. Houve atendimento médico previamente à morte em quatro periciados. Quanto às alterações externas, três indivíduos apresentaram cianose cutâneo-mucosa. O cheiro de amêndoas amargas e a coloração avermelhada da pele ou dos livores não foram descritos em nenhum dos casos. Ao exame interno, as alterações mais prevalentes foram secreção espumosa no interior dos pulmões e petéquias viscerais. Alterações gástricas foram constatadas em três periciados. A alcoolemia foi pesquisada para a maioria, com resultado positivo em dois periciados. Estes dados contribuem para o melhor delineamento epidemiológico das vítimas fatais de cianeto em intoxicações orais, podendo contribuir para o melhor conhecimento destas ocorrências.
Conhecimento científico: enxergamos somente a ponta do iceberg
Authors: Pinke Rodrigues Caio Henrique , Azambuja Amaral Maria Eduarda , Gomes Juliano de Andrade
Published: April 2023

A frase do matemático e PhD Alan Turing traduz, de maneira simples, o entendimento sobre as ciências e, em especial, a forense: mesmo que nós só possamos compreender (“enxergar”) a uma curta distância, já temos a noção de que existe muito trabalho a ser realizado e esta edição demonstra exatamente isso. Com uma série de artigos em formato de revisão bibliográfica, esse volume demonstra a importância de olhar para aquilo que já foi produzido e compreender, de maneira mais assertiva, qual a direção a ser tomada e como as diversas técnicas podem colaborar com os problemas encontrados na prática.
"TANTO MONTA CORTAR COMO DESATAR". SOBRE EL ORIGEN Y FIN DE JUAN GUAS
Authors: Romero Medina Raúl , Marías Fernando
Published: April 2023

Juan Guas fue una de las personalidades más relevantes de la creación artística europea de mediados del siglo XV. Este ensayo aborda el origen de este maestro oriundo de León de Francia, sin posibilidad de error, Lyon para los castellanos de la época, y reflexiona sobre el final de su existencia a través de un espacio de memoria como el de la capilla funeraria que diseña en la iglesia de San Justo y Pastor de Toledo. Uno de los elementos más característicos de esta capilla toledana es la presencia de las jarjas entrecruzadas en su espacio abovedado que, aunque se dieron desde finales del siglo XIV en el conjunto europeo, se observan en la zona rodanesa de Lyon y fueron soluciones llevadas a la Península Ibérica por maestros como Pierre Jalopa o Hanequin Coeman de Bruselas. Bajo las órdenes de este último maestro, aparece documentado por primera vez Juan Guas, en 1452, trabajando junto a su padre, Pedro Guas, en las labores escultóricas de la Puerta de los Leones de la Catedral de Toledo.