bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables S1-S8 from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
Authors: Picaud Sarah , Fedorov Oleg , Thanasopoulou Angeliki , Leonards Katharina , Jones Katherine , Meier Julia , Olzscha Heidi , Monteiro Octovia , Martin Sarah , Philpott Martin , Tumber Anthony , Filippakopoulos Panagis , Yapp Clarence , Wells Christopher , Che Ka Hing , Bannister Andrew , Robson Samuel , Kumar Umesh , Parr Nigel , Lee Kevin , Lugo Dave , Jeffrey Philip , Taylor Simon , Vecellio Matteo L. , Bountra Chas , Brennan Paul E. , O'Mahony Alison , Velichko Sharlene , Müller Susanne , Hay Duncan , Daniels Danette L. , Urh Marjeta , La Thangue Nicholas B. , Kouzarides Tony , Prinjha Rab , Schwaller Jürg , Knapp Stefan
Published: March 2023

I-CBP112 Î”Tm data for bromodomains (S1); I-CBP112 ITC data (S2); Selectivity screening data outside BRD family (S3); ITC data (S4); Data collection and refinement statistics (S5); I-CBP112 deregulated genes 3d KASUMI-1 (S6); I-CBP112 deregulated genes 3d MOLM-13 (S7); I-CBP112 deregulated genes 3d SEM (S8).
Supplementary Figures S1-S7 from Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling
Authors: Hultberg Anna , Morello Virginia , Huyghe Leander , De Jonge Natalie , Blanchetot Christophe , Hanssens Valérie , De Boeck Gitte , Silence Karen , Festjens Els , Heukers Raimond , Roux Benjamin , Lamballe Fabienne , Ginestier Christophe , Charafe-Jauffret Emmanuelle , Maina Flavio , Brouckaert Peter , Saunders Michael , Thibault Alain , Dreier Torsten , de Haard Hans , Michieli Paolo
Published: March 2023

Supplementary Figures S1-S7. WT52 inhibits both HGF-dependent and -independent MET autophosphorylation (S1); MET-targeted ADCC prevents tumor recurrence and suppresses metastatic dissemination in an adjuvant orthotopic model of mammary carcinoma (S2); Circulating tumor cell number shows direct correlation with the extent of metastatic dissemination (S3); Germlining of the WT52 antibody (S4); ARGX-111, an antagonistic anti-MET antibody endowed with enhanced ADCC activity (S5); ARGX-111 reduces total MET protein levels without promoting receptor shedding (S6); ARGX-111 displays enhanced ADCC compared to fucosylated G52 (S7).
Supplementary Materials and Methods from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Authors: Kang Jin Muk , Park Sujin , Kim Staci Jakyong , Kim Hyojung , Lee Bona , Kim Junil , Park Jinah , Kim Shin Tae , Yang Han-Kwang , Kim Woo Ho , Kim Seong-Jin
Published: March 2023

Supplementary Materials and Methods
Supplemental Figure 2 from Colon Cancer Growth and Dissemination Relies upon Thrombin, Stromal PAR-1, and Fibrinogen
Authors: Adams Gregory N. , Rosenfeldt Leah , Frederick Malinda , Miller Whitney , Waltz Dusty , Kombrinck Keith , McElhinney Kathryn E. , Flick Matthew J. , Monia Brett P. , Revenko Alexey S. , Palumbo Joseph S.
Published: March 2023

Supplemental Figure 2. Tumor growth was similar in FXIII-/- (n = 6) and control (n = 8) male mice following injection of MC38 cells into dorsal subcutis as measured by serial calipation and tumor mass at sacrifice.
Supplementary Figure S4 from Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR–Ligand Off-Rates Measurements on Living Cells
Authors: Hebeisen Michael , Schmidt Julien , Guillaume Philippe , Baumgaertner Petra , Speiser Daniel E. , Luescher Immanuel , Rufer Nathalie
Published: March 2023

Supplementary Figure S4. Monomeric TCR-pMHC kinetics of tumor-specific CD8+ T cell subpopulations according to the TRBV repertoire usage.
Supplementary Figure S1 from Ormeloxifene Suppresses Desmoplasia and Enhances Sensitivity of Gemcitabine in Pancreatic Cancer
Authors: Khan Sheema , Ebeling Mara C. , Chauhan Neeraj , Thompson Paul A. , Gara Rishi K. , Ganju Aditya , Yallapu Murali M. , Behrman Stephen W. , Zhao Haotian , Zafar Nadeem , Singh Man Mohan , Jaggi Meena , Chauhan Subhash C.
Published: March 2023

Supplementary Figure S1. ORM inhibits proliferation and invasion of PDAC cells.
Supplementary Figure S3 from Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR–Ligand Off-Rates Measurements on Living Cells
Authors: Hebeisen Michael , Schmidt Julien , Guillaume Philippe , Baumgaertner Petra , Speiser Daniel E. , Luescher Immanuel , Rufer Nathalie
Published: March 2023

Supplementary Figure S3. Monomeric dissociation half-lives of naturally occurring or vaccine-induced tumor-specific CD8+ T cell clones from three melanoma patients.
Supplemental Figure Legend from The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module
Authors: Chen Ke , Wu Kongming , Jiao Xuanmao , Wang Liping , Ju Xiaoming , Wang Min , Di Sante Gabriele , Xu Shaohua , Wang Qiong , Li Kevin , Sun Xin , Xu Congwen , Li Zhiping , Casimiro Mathew C. , Ertel Adam , Addya Sankar , McCue Peter A. , Lisanti Michael P. , Wang Chenguang , Davis Richard J. , Mardon Graeme , Pestell Richard G.
Published: March 2023

Supplemental Figure Legend from The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module
supplementary figure 3 from Enhanced MET Translation and Signaling Sustains K-Ras–Driven Proliferation under Anchorage-Independent Growth Conditions
Authors: Fujita-Sato Saori , Galeas Jacqueline , Truitt Morgan , Pitt Cameron , Urisman Anatoly , Bandyopadhyay Sourav , Ruggero Davide , McCormick Frank
Published: March 2023

supplementary figure 3. HGF, but not EGF, plays an essential role in proliferation of cells in anchorage independent culture conditions.
supplementary figure 2 from Enhanced MET Translation and Signaling Sustains K-Ras–Driven Proliferation under Anchorage-Independent Growth Conditions
Authors: Fujita-Sato Saori , Galeas Jacqueline , Truitt Morgan , Pitt Cameron , Urisman Anatoly , Bandyopadhyay Sourav , Ruggero Davide , McCormick Frank
Published: March 2023

supplementary figure 2. K-Ras is required for anchorage independent growth in a broad panel of K-Ras mutant cells.
Supplementary Figures 1 - 6, Tables 1 - 3 from Amplification of Long Noncoding RNA ZFAS1 Promotes Metastasis in Hepatocellular Carcinoma
Authors: Li Tao , Xie Junjie , Shen Chuan , Cheng Dongfeng , Shi Yuan , Wu Zhichong , Deng Xiaxing , Chen Hao , Shen Baiyong , Peng Chenghong , Li Hongwei , Zhan Qian , Zhu Zhecheng
Published: March 2023

Supplementary Figure S1. Differentially expressed lncRNAs between HCC tissues and pair non-tumor tissues. Supplementary Figure S2. Co-expression network analysis. Supplementary Figure S3. qPCR analysis of lncRNAs. Supplementary Figure S4. qPCR analysis of miR-150 in HCC. Supplementary Figure S5. qPCR analysis of miR-150. Supplementary Figure S6. ZFAS1 positively regulates ZEB1, MMP14 and MMP16 expression in vivo. Supplementary Table S1. qPCR primers and siRNA sequences used in the study. Supplementary Table S2. Consistently upregulated or downregulated lncRNAs in GSE55191 and GSE58043 (Fold change>4.0, p<0.05) Supplementary Table S3. Core lncRNAs in the co-expression network analysis.
Supplemtal figure legends 1-5 from Enhanced MET Translation and Signaling Sustains K-Ras–Driven Proliferation under Anchorage-Independent Growth Conditions
Authors: Fujita-Sato Saori , Galeas Jacqueline , Truitt Morgan , Pitt Cameron , Urisman Anatoly , Bandyopadhyay Sourav , Ruggero Davide , McCormick Frank
Published: March 2023

Supplemtal figure legends 1-5
Supplementary Methods and References from ADAPT, a Novel Scaffold Protein-Based Probe for Radionuclide Imaging of Molecular Targets That Are Expressed in Disseminated Cancers
Authors: Garousi Javad , Lindbo Sarah , Nilvebrant Johan , Åstrand Mikael , Buijs Jos , Sandström Mattias , Honarvar Hadis , Orlova Anna , Tolmachev Vladimir , Hober Sophia
Published: March 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figures S1-S9 from ADAPT, a Novel Scaffold Protein-Based Probe for Radionuclide Imaging of Molecular Targets That Are Expressed in Disseminated Cancers
Authors: Garousi Javad , Lindbo Sarah , Nilvebrant Johan , Åstrand Mikael , Buijs Jos , Sandström Mattias , Honarvar Hadis , Orlova Anna , Tolmachev Vladimir , Hober Sophia
Published: March 2023

Analytical RP-HPLC analysis of purified DOTA-C-(HE)3-ADAPT6 ; Mass spectrum of purified DOTA-C-(HE)3-ADAPT6 ; Overlay of circular dichroism spectra from 250-195 nm for DOTA-C-(HE)3-ADAPT6 before (blue) and after (red) heating from 20-90{degree sign}C ; Normalized relative ellipticity of DOTA-C-(HE)3-ADAPT6 at 221 nm as a function of temperature ; SDS-PAGE analysis of 111In-DOTA-C-(HE)3-ADAPT6 ; Representative binding curve of the LigandTracer measurement of 111In-DOTA-C-(HE)3-ADAPT6 affinity using SKOV-3 cells ; InteractionMap of 111In-DOTA-C-(HE)3-ADAPT6 binding to SKOV-3 cells ; In vivo targeting specificity of 111In-DOTA-C-(HE)3-ADAPT6 (3 µg) in mice bearing SKOV-3 xenografts at 1 h p.i ; Biodistribution of 111In-DOTA-C-(HE)3-ADAPT6 in mice bearing SKOV-3 xenografts .
Supplementary Table S5 from Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis
Authors: Robertson Chadia L. , Srivastava Jyoti , Siddiq Ayesha , Gredler Rachel , Emdad Luni , Rajasekaran Devaraja , Akiel Maaged , Shen Xue-Ning , Guo Chunqing , Giashuddin Shah , Wang Xiang-Yang , Ghosh Shobha , Subler Mark A. , Windle Jolene J. , Fisher Paul B. , Sarkar Devanand
Published: March 2023

List of differentially expressed genes in the livers of AEGâ€�1KO versus WT mouse.
Supplementary Figures S1-S5 from Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis
Authors: Robertson Chadia L. , Srivastava Jyoti , Siddiq Ayesha , Gredler Rachel , Emdad Luni , Rajasekaran Devaraja , Akiel Maaged , Shen Xue-Ning , Guo Chunqing , Giashuddin Shah , Wang Xiang-Yang , Ghosh Shobha , Subler Mark A. , Windle Jolene J. , Fisher Paul B. , Sarkar Devanand
Published: March 2023

Generation of AEG-1KO mouse (S1); Analysis of spleen cells of adult WT and AEG-1KO mice (S2); F4/80 staining for macrophages in spleen sections of aged (16 m) WT and AEG-1KO mouse. Magnification 400X (S3); Graphical representation of quantification of F4/80 staining for macrophages in liver sections of WT and AEG-1KO mice, either untreated (naÃ¯ve) or treated with DEN or DEN/PB (S4); Stellate cells are activated in the tumor region of WT liver (S5).
Supplementary Figures S1-S4 from Usp28 Counteracts Fbw7 in Intestinal Homeostasis and Cancer
Authors: Diefenbacher Markus E. , Chakraborty Atanu , Blake Sophia M. , Mitter Richard , Popov Nikita , Eilers Martin , Behrens Axel
Published: March 2023

Supplementary Figures S1-S4. Loss of Usp28 ameliorates the Fbw7 inactivation phenotype and partly restores cell differentiation in the intestine (S1); Deletion of Usp28 prolongs life expectancy and reduces tumor burden in the Fbw7-deleted APCmin/+ intestinal tumour model (S2); The interaction between Usp28 and its substrate c-Myc is independent of Fbw7 (S3); Schematic representation of Usp28-Fbw7-substrate crosstalk in Fbw7-proficient and deficient cells and speculative model of the consequences of this crosstalk in the intestinal crypt (S4).
Supplemental Table 1 from Gain of Glucose-Independent Growth upon Metastasis of Breast Cancer Cells to the Brain
Authors: Chen Jinyu , Lee Ho-Jeong , Wu Xuefeng , Huo Lei , Kim Sun-Jin , Xu Lei , Wang Yan , He Junqing , Bollu Lakshmi R. , Gao Guang , Su Fei , Briggs James , Liu Xiaojing , Melman Tamar , Asara John M. , Fidler Isaiah J. , Cantley Lewis C. , Locasale Jason W. , Weihua Zhang
Published: March 2023

Supplemental Table 1. MS intensity value (MSIV per 1.0Ã—106 cells) of 13C labeled metabolites shown in Figure 5D-5N
Supplementary Table 1 from Notch Suppresses Angiogenesis and Progression of Hepatic Metastases
Authors: Banerjee Debarshi , Hernandez Sonia L. , Garcia Alejandro , Kangsamaksin Thaned , Sbiroli Emily , Andrews John , Forrester Lynn Ann , Wei Na , Kadenhe-Chiweshe Angela , Shawber Carrie J. , Kitajewski Jan K. , Kandel Jessica J. , Yamashiro Darrell J.
Published: March 2023

Supplementary Table 1. Antibodies utilized in this study.
Supplementary Methods from Notch Suppresses Angiogenesis and Progression of Hepatic Metastases
Authors: Banerjee Debarshi , Hernandez Sonia L. , Garcia Alejandro , Kangsamaksin Thaned , Sbiroli Emily , Andrews John , Forrester Lynn Ann , Wei Na , Kadenhe-Chiweshe Angela , Shawber Carrie J. , Kitajewski Jan K. , Kandel Jessica J. , Yamashiro Darrell J.
Published: March 2023

Supplementary Methods. Reverse transcription and quantitative PCR. BrdU Proliferation Assay. In vivo BrdU assay. Migration and Invasion Assays. Adenovirus production and Injection. siRNA transfection.
Supplementary Figures S1-S12 and Legends from Notch Suppresses Angiogenesis and Progression of Hepatic Metastases
Authors: Banerjee Debarshi , Hernandez Sonia L. , Garcia Alejandro , Kangsamaksin Thaned , Sbiroli Emily , Andrews John , Forrester Lynn Ann , Wei Na , Kadenhe-Chiweshe Angela , Shawber Carrie J. , Kitajewski Jan K. , Kandel Jessica J. , Yamashiro Darrell J.
Published: March 2023

Supplementary Figures S1-S12 and Legends. Supplementary Figure S1. Combined Inhibition of Notch and VEGF disrupts interaction of pericytes with endothelial cells in primary tumors Supplementary Figure S2. Inhibition of Notch increases liver metastases. Supplementary Figure S3. Inhibition of Notch increases liver metastases as measured by bioluminescence in liver homogenates. Supplementary Figure S4. Notch blockade does not increase metastases to other organs. Supplementary Figure S5. N1D does not affect proliferation, invasion or migration of neuroblastoma cell lines. Supplementary Figure S6. N1KD decreases Hes1 and Hey1 but does not affect proliferation of NGP cells Supplementary Figure S7. Increased vasculature of liver metastases with Notch blockade Supplementary Figure S8. Activation of HSCs in liver metastases with Notch blockade Supplementary Figure S9. SEC expression of ICAM-1 is regulated by Notch Supplementary Figure S10. AdN1D increases expression of liver ICAM-1 but does not increase retention of tumor cells in the liver. Supplementary Figure S11. Notch1 decoy variants increase proliferation of mSEC but not NGP cells Supplementary Figure S12. Jag1 siRNA decreases expression of Jag1 in NGP cells.
Supplementary Tables 1 and 2, Figure 1 from TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer
Authors: Li Jun , Han Leng , Roebuck Paul , Diao Lixia , Liu Lingxiang , Yuan Yuan , Weinstein John N. , Liang Han
Published: March 2023

Supplementary Tables 1 and 2, Figure 1. Supplementary Table 1: Summary of known tumor subtypes in TCGA datasets Supplementary Table 2: List of clinically actionable genes Supplementary Figure 1: The Kaplan-Meier plot of lncRNA-expression subtypes in another independent KIRC cohort
Supplementary Tables S1-S3 from Heterochromatin Protein HP1γ Promotes Colorectal Cancer Progression and Is Regulated by miR-30a
Authors: Liu Ming , Huang Feifei , Zhang Dan , Ju Junyi , Wu Xiao-Bin , Wang Ying , Wang Yadong , Wu Yupeng , Nie Min , Li Zhuchen , Ma Chi , Chen Xi , Zhou Jin-Yong , Tan Renxiang , Yang Bo-Lin , Zen Ke , Zhang Chen-Yu , Chen Yu-Gen , Zhao Quan
Published: March 2023

Clinicopathologic characteristics of HP1y expression in CRC patients (S1); Real-time PCR primer sequences (S2); ChIP primer sequences for p21 promoter (S3).
Supplementary Table 1 from Interferon Regulatory Factor-1 Signaling Regulates the Switch between Autophagy and Apoptosis to Determine Breast Cancer Cell Fate
Authors: Schwartz-Roberts Jessica L. , Cook Katherine L. , Chen Chun , Shajahan-Haq Ayesha N. , Axelrod Margaret , Wärri Anni , Riggins Rebecca B. , Jin Lu , Haddad Bassem R. , Kallakury Bhaskar V. , Baumann William T. , Clarke Robert
Published: March 2023

Patient/tumor characteristics of human breast cancer tissue microarrays.
Supplementary Figure 2 from Interferon Regulatory Factor-1 Signaling Regulates the Switch between Autophagy and Apoptosis to Determine Breast Cancer Cell Fate
Authors: Schwartz-Roberts Jessica L. , Cook Katherine L. , Chen Chun , Shajahan-Haq Ayesha N. , Axelrod Margaret , Wärri Anni , Riggins Rebecca B. , Jin Lu , Haddad Bassem R. , Kallakury Bhaskar V. , Baumann William T. , Clarke Robert
Published: March 2023

Nuclear IRF1 is induced following ATG7 and BECN1 knockdown.
Supplementary Figure 1 from Interferon Regulatory Factor-1 Signaling Regulates the Switch between Autophagy and Apoptosis to Determine Breast Cancer Cell Fate
Authors: Schwartz-Roberts Jessica L. , Cook Katherine L. , Chen Chun , Shajahan-Haq Ayesha N. , Axelrod Margaret , Wärri Anni , Riggins Rebecca B. , Jin Lu , Haddad Bassem R. , Kallakury Bhaskar V. , Baumann William T. , Clarke Robert
Published: March 2023

Model ranges, their range, and description.
Supplementary Materials and Methods from Human Helicase RECQL4 Drives Cisplatin Resistance in Gastric Cancer by Activating an AKT–YB1–MDR1 Signaling Pathway
Authors: Mo Dongliang , Fang Hongbo , Niu Kaifeng , Liu Jing , Wu Meng , Li Shiyou , Zhu Tienian , Aleskandarany Mohammed A. , Arora Arvind , Lobo Dileep N. , Madhusudan Srinivasan , Balajee Adayabalam S. , Chi Zhenfen , Zhao Yongliang
Published: March 2023

1. Construction of Tissue Microarray (TMA). 2. Chemicals. 3. Real-time PCR. 4. Dual-Luciferase assay for MVP. 5. In vitro pull-down assay. 6. Co-immunoprecipitation. 7. Protein expression and purification. 8. Chromatin immunoprecipitation analysis 9. Electrophoretic mobility shift assays (EMSAs). 10.PCR-SSCP protocol.
Supplementary Figure S8 from CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity
Authors: Boyle Samantha E. , Fedele Clare G. , Corbin Vincent , Wybacz Elisha , Szeto Pacman , Lewin Jeremy , Young Richard J. , Wong Annie , Fuller Robert , Spillane John , Speakman David , Donahoe Simon , Pohl Miklos , Gyorki David , Henderson Michael A. , Johnstone Ricky W. , Papenfuss Anthony T. , Shackleton Mark
Published: March 2023

Genomic copy number differences among CD271- and CD271+ cells from PDX melanomas.
Supplementary Figure S5 from CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity
Authors: Boyle Samantha E. , Fedele Clare G. , Corbin Vincent , Wybacz Elisha , Szeto Pacman , Lewin Jeremy , Young Richard J. , Wong Annie , Fuller Robert , Spillane John , Speakman David , Donahoe Simon , Pohl Miklos , Gyorki David , Henderson Michael A. , Johnstone Ricky W. , Papenfuss Anthony T. , Shackleton Mark
Published: March 2023

Variable re-expression patterns in PDX tumors generated from CD271- and CD271+ cells.
Video 4 from Impact of Metabolic Heterogeneity on Tumor Growth, Invasion, and Treatment Outcomes
Authors: Robertson-Tessi Mark , Gillies Robert J. , Gatenby Robert A. , Anderson Alexander R.A.
Published: March 2023

Video 4: Chemotherapy. Simulation of chemotherapy
Supplementary Figure S2 from CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity
Authors: Boyle Samantha E. , Fedele Clare G. , Corbin Vincent , Wybacz Elisha , Szeto Pacman , Lewin Jeremy , Young Richard J. , Wong Annie , Fuller Robert , Spillane John , Speakman David , Donahoe Simon , Pohl Miklos , Gyorki David , Henderson Michael A. , Johnstone Ricky W. , Papenfuss Anthony T. , Shackleton Mark
Published: March 2023

Clinico-pathological characteristics of patients who donated melanomas.
Supplementary Figure S1 from CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity
Authors: Boyle Samantha E. , Fedele Clare G. , Corbin Vincent , Wybacz Elisha , Szeto Pacman , Lewin Jeremy , Young Richard J. , Wong Annie , Fuller Robert , Spillane John , Speakman David , Donahoe Simon , Pohl Miklos , Gyorki David , Henderson Michael A. , Johnstone Ricky W. , Papenfuss Anthony T. , Shackleton Mark
Published: March 2023

Comparison of different methods previously used to test the CD271-based cancer stem cell model in human melanoma.
Supplementary Table 2 from Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy
Authors: Maby Pauline , Tougeron David , Hamieh Mohamad , Mlecnik Bernhard , Kora Hafid , Bindea Gabriela , Angell Helen K. , Fredriksen Tessa , Elie Nicolas , Fauquembergue Emilie , Drouet Aurélie , Leprince Jérôme , Benichou Jacques , Mauillon Jacques , Le Pessot Florence , Sesboüé Richard , Tuech Jean-Jacques , Sabourin Jean-Christophe , Michel Pierre , Frébourg Thierry , Galon Jérôme , Latouche Jean-Baptiste
Published: March 2023

Association between clinical characteristics and number of frameshift mutations.
Supplementary Tables S1-S2 from M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
Authors: Van Overmeire Eva , Stijlemans Benoît , Heymann Felix , Keirsse Jiri , Morias Yannick , Elkrim Yvon , Brys Lea , Abels Chloé , Lahmar Qods , Ergen Can , Vereecke Lars , Tacke Frank , De Baetselier Patrick , Van Ginderachter Jo A. , Laoui Damya
Published: March 2023

Antibodies for flow cytometry (S1); List of gene specific primer sequences for qRT-PCR (S2).
Supplementary Methods from M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
Authors: Van Overmeire Eva , Stijlemans Benoît , Heymann Felix , Keirsse Jiri , Morias Yannick , Elkrim Yvon , Brys Lea , Abels Chloé , Lahmar Qods , Ergen Can , Vereecke Lars , Tacke Frank , De Baetselier Patrick , Van Ginderachter Jo A. , Laoui Damya
Published: March 2023

Description of additional methods and procedures used in the study.
Supplementary Figure S3 from RAGE Mediates S100A7-Induced Breast Cancer Growth and Metastasis by Modulating the Tumor Microenvironment
Authors: Nasser Mohd W. , Wani Nissar Ahmad , Ahirwar Dinesh K. , Powell Catherine A. , Ravi Janani , Elbaz Mohamad , Zhao Helong , Padilla Laura , Zhang Xiaoli , Shilo Konstantin , Ostrowski Michael , Shapiro Charles , Carson William E. , Ganju Ramesh K.
Published: March 2023

RAGE/mS100a7a15 axis enhances M2 macrophage recruitment to lungs.
Supplementary Movie 2 from Urokinase Exerts Antimetastatic Effects by Dissociating Clusters of Circulating Tumor Cells
Authors: Choi Jin Woo , Kim Jun Ki , Yang Yun Jung , Kim Pilhan , Yoon Kwon-Ha , Yun Seok Hyun
Published: March 2023

For Fig 3E
Supplemental Figure S1 from Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer
Authors: Davidson Laurie A. , Callaway Evelyn S. , Kim Eunjoo , Weeks Brad R. , Fan Yang-Yi , Allred Clinton D. , Chapkin Robert S.
Published: March 2023

Time line for initiation and inflammation-associated tumor studies.
Supplementary Figure 1 from Tumor-Derived Osteopontin Reprograms Normal Mammary Fibroblasts to Promote Inflammation and Tumor Growth in Breast Cancer
Authors: Sharon Yoray , Raz Yael , Cohen Noam , Ben-Shmuel Amir , Schwartz Hila , Geiger Tamar , Erez Neta
Published: March 2023

Figure S1: OPN does not affect NMFs proliferation.
Supplemental Table S1 from A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor–Resistant Lung Tumors
Authors: Moores Sheri L. , Chiu Mark L. , Bushey Barbara S. , Chevalier Kristen , Luistro Leopoldo , Dorn Keri , Brezski Randall J. , Haytko Peter , Kelly Thomas , Wu Sheng-Jiun , Martin Pauline L. , Neijssen Joost , Parren Paul W.H.I. , Schuurman Janine , Attar Ricardo M. , Laquerre Sylvie , Lorenzi Matthew V. , Anderson G. Mark
Published: March 2023

Origins and Genotypes of Lung Cancer Tumor Cell Lines
Supplementary Information from Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer
Authors: Ye Fu-Gui , Song Chuan-Gui , Cao Zhi-Gang , Xia Chen , Chen Dan-Na , Chen Li , Li Shan , Qiao Feng , Ling Hong , Yao Ling , Hu Xin , Shao Zhi-Ming
Published: March 2023

Supplementary Methods
Supplementary Tables from HTLV-1 bZIP Factor RNA and Protein Impart Distinct Functions on T-cell Proliferation and Survival
Authors: Mitobe Yuichi , Yasunaga Jun-ichirou , Furuta Rie , Matsuoka Masao
Published: March 2023

Primers and siRNAs used in this study
Suppl. Movie 1 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Authors: Prunier Chloé , Josserand Véronique , Vollaire Julien , Beerling Evelyne , Petropoulos Christos , Destaing Olivier , Montemagno Christopher , Hurbin Amandine , Prudent Renaud , de Koning Leanne , Kapur Reuben , Cohen Pascale A. , Albiges-Rizo Corinne , Coll Jean-Luc , van Rheenen Jacco , Billaud Marc , Lafanechère Laurence
Published: March 2023

FRAP analysis of actin dynamics in invadopodia treated with vehicle or Pyr1
Supp. Figure 7 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Authors: Prunier Chloé , Josserand Véronique , Vollaire Julien , Beerling Evelyne , Petropoulos Christos , Destaing Olivier , Montemagno Christopher , Hurbin Amandine , Prudent Renaud , de Koning Leanne , Kapur Reuben , Cohen Pascale A. , Albiges-Rizo Corinne , Coll Jean-Luc , van Rheenen Jacco , Billaud Marc , Lafanechère Laurence
Published: March 2023

In vivo analysis of the Pyr1 effect on LIMKs activity markers
Supp. Figure 3 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Authors: Prunier Chloé , Josserand Véronique , Vollaire Julien , Beerling Evelyne , Petropoulos Christos , Destaing Olivier , Montemagno Christopher , Hurbin Amandine , Prudent Renaud , de Koning Leanne , Kapur Reuben , Cohen Pascale A. , Albiges-Rizo Corinne , Coll Jean-Luc , van Rheenen Jacco , Billaud Marc , Lafanechère Laurence
Published: March 2023

Weight and behavior monitoring of mice used in the TS/A-pGL3 xenografts experiment
supplementary figure legends, supplementary Tables, supplementary methods from ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors
Authors: Cifaldi Loredana , Romania Paolo , Falco Michela , Lorenzi Silvia , Meazza Raffaella , Petrini Stefania , Andreani Marco , Pende Daniela , Locatelli Franco , Fruci Doriana
Published: March 2023

This file contains supplementary figure legends, supplementary Tables, supplementary methods and supplementary references.
List of Speakers from 26th Pezcoller Symposium: Cancers Driven by Hormones
Authors: Brown Myles , Chinnaiyan Arul , Farsetti Antonella , Livingston David M. , Loda Massimo , Schuele Roland , Mihich Enrico
Published: March 2023

List of Speakers
Figure S1 from ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors
Authors: Cifaldi Loredana , Romania Paolo , Falco Michela , Lorenzi Silvia , Meazza Raffaella , Petrini Stefania , Andreani Marco , Pende Daniela , Locatelli Franco , Fruci Doriana
Published: March 2023

Supplementary Figure S1 shows ERAP1 expression in HeLa cells transduced with different ERAP1 shRNA constructs
Supplementary materials and methods from Antitumor Immunity Triggered by Melphalan Is Potentiated by Melanoma Cell Surface–Associated Calreticulin
Authors: Dudek-Perić Aleksandra M. , Ferreira Gabriela B. , Muchowicz Angelika , Wouters Jasper , Prada Nicole , Martin Shaun , Kiviluoto Santeri , Winiarska Magdalena , Boon Louis , Mathieu Chantal , van den Oord Joost , Stas Marguerite , Gougeon Marie-Lise , Golab Jakub , Garg Abhishek D. , Agostinis Patrizia
Published: March 2023

Supplementary materials and methods
Supplemental Figure 2 from Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival
Authors: Stiehl Thomas , Baran Natalia , Ho Anthony D. , Marciniak-Czochra Anna
Published: March 2023

Supplemental Figure 2. The figure depicts estimated LSC properties for the subgroup of FLT3-ITD (a typical leukemogenetic mutation) positive patients.
Supplementary Materials and Methods, reference, Figure Legends from miR340 Suppresses the Stem-like Cell Function of Glioma-Initiating Cells by Targeting Tissue Plasminogen Activator
Authors: Yamashita Daisuke , Kondo Toru , Ohue Shiro , Takahashi Hisaaki , Ishikawa Madoka , Matoba Ryo , Suehiro Satoshi , Kohno Shohei , Harada Hironobu , Tanaka Junya , Ohnishi Takanori
Published: March 2023

Supplementary Materials and Methods, reference, Figure Legends
Supplementary Figures S1-S10 from miR340 Suppresses the Stem-like Cell Function of Glioma-Initiating Cells by Targeting Tissue Plasminogen Activator
Authors: Yamashita Daisuke , Kondo Toru , Ohue Shiro , Takahashi Hisaaki , Ishikawa Madoka , Matoba Ryo , Suehiro Satoshi , Kohno Shohei , Harada Hironobu , Tanaka Junya , Ohnishi Takanori
Published: March 2023

Supplementary Figures S1-10 Supplementary Figure S1. Characterization of hGICs demonstrates the stemness nature of the cells. Supplementary Figure S2. miR-340 transfection causes a markedly elevated level of miR-340 expression in hGICs compared with the control. Supplementary Figure S3. miR-340 overexpression in glioma cell lines moderately inhibits tumorigenesis in vivo. Supplementary Figure S4. miR-340 overexpression affects the expression of the genes related to two signaling pathways. Supplementary Figure S5. Inhibition of PLAT expression by miR-340 overexpression in hGICs and co-immunolocalization of PLAT and CD15 in GBM tissues. Supplementary Figure S6. Knockdown efficiency of the PLAT-shRNA expression vector. Supplementary Figure S7. Effects of PLAT-shRNA are due to the specific inhibition of PLAT in hGICs. Supplementary Figure S8. Inhibitory effects of miR-340-overexpressing hGICs on in vitro cell functions are recovered by PLAT introduction. Supplementary Figure S9. Microarray analysis on the expression of c-Met, CD44, Sox2, DNMT1, ANXA2, and CDKN1A genes in hGICs by miR-340 overexpression. Supplementary Figure S10. Survival curves of glioma patients with different expression levels of plat.
Supplementary data for publication from Three-Dimensional Breast Cancer Models Mimic Hallmarks of Size-Induced Tumor Progression
Authors: Singh Manjulata , Mukundan Shilpaa , Jaramillo Maria , Oesterreich Steffi , Sant Shilpa
Published: March 2023

Supplementary Materials and Methods
Supplementary Figure S2 from Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance
Authors: Krumm Andrea , Barckhausen Christina , Kücük Pelin , Tomaszowski Karl-Heinz , Loquai Carmen , Fahrer Jörg , Krämer Oliver Holger , Kaina Bernd , Roos Wynand Paul
Published: March 2023

Class I HDAC inhibition by VPA does not influence the cell cycle distribution or the replication rate of melanoma cell lines. (A) HDACs were inhibited with VPA (1 mM for 168 h) in D05 and A375 melanoma cells and cell cycle distribution was determined using PI stained cells and flow cytometry. (B) HDACs were inhibited with VPA (1 mM for 168 h) in D05 and A375 melanoma cells, VPA was removed by medium change and growth rates were determined by counting the cells at indicated time points after VPA removal.
Supplementary Figure S1 from Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance
Authors: Krumm Andrea , Barckhausen Christina , Kücük Pelin , Tomaszowski Karl-Heinz , Loquai Carmen , Fahrer Jörg , Krämer Oliver Holger , Kaina Bernd , Roos Wynand Paul
Published: March 2023

HDAC1, 2 and 3 expression in melanomas. (A) Microarray expression data of HDAC1, HDAC2 and HDAC3 from 45 primary melanoma,18 benign skin nevi, and 7 normal skin tissue specimens. (B) Western blot analysis of HDAC1, HDAC2, HDAC3 and HDAC8 protein levels in the melanoma cell lines D05, G361, SK-Mel187, Mel537, A2058 and A375 compared to the normal (non-cancerous) cells PBLCs, VH10tert and Hema-LP. β-actin served as loading control. Relative expression (R.E.) compared to the lowest protein level is indicated. (C) Relative HDAC protein level in melanoma cells (D05, G361, Mel187, Mel537, A2058 and A375) compared to non-cancerous (PBLCs, VH10tert and Hema-LP) cells as determined by Western blot analysis. (D) Western blot analysis of acetylated-H3 in Hema-LP, PBLCs and VH10tert cells following VPA treatment (1mM for 168 h). H3 was used as loading control. **p<0.005, ***p<0.0001.
Supplementary Figure legends from Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma
Authors: Massó-Vallés Daniel , Jauset Toni , Serrano Erika , Sodir Nicole M. , Pedersen Kim , Affara Nesrine I. , Whitfield Jonathan R. , Beaulieu Marie-Eve , Evan Gerard I. , Elias Laurence , Arribas Joaquín , Soucek Laura
Published: March 2023

Supplementary Figure legends
Supplementary Figure S7 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Figure S7: Representative examples of E-cadherin, ABCG2, and CD133 staining using cells derived from the xenografts, related to Fig. 5F.
Supplementary Figure S6 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Figure S6: β-catenin/E-cadherin/Sox15 and β-catenin/Twist1/TCF4 possess opposing effects in regulating Wnt-elicited promotion of the CSC phenotype in CL1-0 and CL1-5 cells.
Supplementary Figure S2 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Figure S2: Representative examples of E-cadherin staining using cells after subsequent serial selection (LM-HM20) are indicated (see Fig. 1A).
Supplemental figures legends from FGFR1 Induces Glioblastoma Radioresistance through the PLCγ/Hif1α Pathway
Authors: Gouazé-Andersson Valérie , Delmas Caroline , Taurand Marion , Martinez-Gala Judith , Evrard Solène , Mazoyer Sandrine , Toulas Christine , Cohen-Jonathan-Moyal Elizabeth
Published: March 2023

Supplemental figures legends for Supplemental Figures 1 and 2
Supplemental Figure 1 from FGFR1 Induces Glioblastoma Radioresistance through the PLCγ/Hif1α Pathway
Authors: Gouazé-Andersson Valérie , Delmas Caroline , Taurand Marion , Martinez-Gala Judith , Evrard Solène , Mazoyer Sandrine , Toulas Christine , Cohen-Jonathan-Moyal Elizabeth
Published: March 2023

FGFRs expression was determined by qPCR in LN18 cells.
Supplementary Figure S3 from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Target genes with extensive regulation by miRs ({greater than or equal to} 5) predicted by TargetScan and DIANAmicroT.
Supplementary Experimental Procedures from RIP1 Kinase Is an Oncogenic Driver in Melanoma
Authors: Liu Xiao Ying , Lai Fritz , Yan Xu Guang , Jiang Chen Chen , Guo Su Tang , Wang Chun Yan , Croft Amanda , Tseng Hsin-Yi , Wilmott James S. , Scolyer Richard A. , Jin Lei , Zhang Xu Dong
Published: March 2023

Supplementary Experimental Procedures
Supplementary Figure S2 from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Validation of the most abundantly deregulated miRs.
Supplementary Figure Legends from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Supplementary Figure Legends from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Supplementary Dataset S3 from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Deregulated mRNAs in PTC.
Supplementary Dataset S1 from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Detected miRs in normal and tumor thyroid tissues.
Tables S5-S8 from A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis
Authors: Remy Elisabeth , Rebouissou Sandra , Chaouiya Claudine , Zinovyev Andrei , Radvanyi François , Calzone Laurence
Published: March 2023

Mutant analyses; Table S5: Systematic analysis of model perturbations; single mutations that suppress or force a phenotype; Table S6: Systematic analysis of model perturbations; double mutations that suppress or force a phenotype; Table S7: Practical use of automatic search for triple mutations; third alterations that suppress the growth arrest phenotype in an FGFR3 & PIK3CA-context; and Table S8: Practical use of automatic search for triple mutations; third alterations that suppress the growth arrest phenotype in a FGFR3 & CDKN2A-context.
Supplementary Figure 2 from Modification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach
Authors: Suarez Giovanni , Romero-Gallo Judith , Piazuelo M. Blanca , Wang Ge , Maier Robert J. , Forsberg Lennart S. , Azadi Parastoo , Gomez Martin A. , Correa Pelayo , Peek Richard M.
Published: March 2023

Supplemental Figure 2. A. Quantitative real time RT-PCR was used to determine expression levels of NOD1 in AGS cells stably transfected with a non-targeting shRNA or NOD1-specific shRNA. Three different single cell colonies (col) transfected with each shRNA were tested. Data are represented as fold NOD1 mRNA expression relative to the mean expression level in Non-targeting control cells. B. Quantitative real time RT-PCR was used to determine expression levels of TRAF3 in AGS cells transiently transfected with either non-targeting shRNA or TRAF3-specific shRNA. Bars represent the mean{plus minus}SEM of TRAF3 transcripts in cell transfected with TRAF3-specific shRNA relative to the mean expression level in cells transfected with non-targeting shRNA. Data are represented as mean{plus minus}SEM from 2 independent experiments.
Figure S2 from A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis
Authors: Remy Elisabeth , Rebouissou Sandra , Chaouiya Claudine , Zinovyev Andrei , Radvanyi François , Calzone Laurence
Published: March 2023

Figure S2. Measure of RB/E2F pathway activation with respect to stage.
Supplemental Methods from Modification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach
Authors: Suarez Giovanni , Romero-Gallo Judith , Piazuelo M. Blanca , Wang Ge , Maier Robert J. , Forsberg Lennart S. , Azadi Parastoo , Gomez Martin A. , Correa Pelayo , Peek Richard M.
Published: March 2023

Supplemental Methods
Figure S1 from A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis
Authors: Remy Elisabeth , Rebouissou Sandra , Chaouiya Claudine , Zinovyev Andrei , Radvanyi François , Calzone Laurence
Published: March 2023

Figure S1. Probabilities of the phenotypes resulting from model analyses (as summarized in Table 2) for the associations listed in Table 1.
Supplementary Video S2 from Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis
Authors: Schaub Franz X. , Reza Md. Shamim , Flaveny Colin A. , Li Weimin , Musicant Adele M. , Hoxha Sany , Guo Min , Cleveland John L. , Amelio Antonio L.
Published: March 2023

Living Image DLIT 3D reconstruction of Emu-Myc Lymphoma-GpNLuc orthotopic allograft transplant.
Supplementary Figure 2 from The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(—)
Authors: Tsuchihashi Kenji , Okazaki Shogo , Ohmura Mitsuyo , Ishikawa Miyuki , Sampetrean Oltea , Onishi Nobuyuki , Wakimoto Hiroaki , Yoshikawa Momoko , Seishima Ryo , Iwasaki Yoshimi , Morikawa Takayuki , Abe Shinya , Takao Ayumi , Shimizu Misato , Masuko Takashi , Nagane Motoo , Furnari Frank B. , Akiyama Tetsu , Suematsu Makoto , Baba Eishi , Akashi Koichi , Saya Hideyuki , Nagano Osamu
Published: March 2023

Sulfasalazine does not affect intracellular ROS levels in Becker or U87MG cells.
Supplemental Table S6 from The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Authors: Harms Paul William , Vats Pankaj , Verhaegen Monique Elise , Robinson Dan R. , Wu Yi-Mi , Dhanasekaran Saravana Mohan , Palanisamy Nallasivam , Siddiqui Javed , Cao Xuhong , Su Fengyun , Wang Rui , Xiao Hong , Kunju Lakshmi P. , Mehra Rohit , Tomlins Scott A. , Fullen Douglas Randall , Bichakjian Christopher Keram , Johnson Timothy M. , Dlugosz Andrzej Antoni , Chinnaiyan Arul M.
Published: March 2023

Supplemental Table S6. Nonsynonymous somatic mutations in MCC tumors
Supplemental Figure S5 from A Urokinase Receptor–Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma
Authors: Wykosky Jill , Hu Jingjing , Gomez German G. , Taylor Tiffany , Villa Genaro R. , Pizzo Donald , VandenBerg Scott R. , Thorne Amy Haseley , Chen Clark C. , Mischel Paul S. , Gonias Steven L. , Cavenee Webster K. , Furnari Frank B.
Published: March 2023

Supplemental Figure S5. MEK inhibition restores sensitivity to EGFR TKi
Supplemental Figure Legends from The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Authors: Harms Paul William , Vats Pankaj , Verhaegen Monique Elise , Robinson Dan R. , Wu Yi-Mi , Dhanasekaran Saravana Mohan , Palanisamy Nallasivam , Siddiqui Javed , Cao Xuhong , Su Fengyun , Wang Rui , Xiao Hong , Kunju Lakshmi P. , Mehra Rohit , Tomlins Scott A. , Fullen Douglas Randall , Bichakjian Christopher Keram , Johnson Timothy M. , Dlugosz Andrzej Antoni , Chinnaiyan Arul M.
Published: March 2023

Supplemental Figure Legends
Supplementary Figure S7 from PIK3CAH1047R Accelerates and Enhances KRASG12D-Driven Lung Tumorigenesis
Authors: Green Shon , Trejo Christy L. , McMahon Martin
Published: March 2023

In vitro proliferation and cell signaling of lung tumor derived cell lines of defined Kras or Pik3ca genotype.
Figure S2 from Interleukin-5 Facilitates Lung Metastasis by Modulating the Immune Microenvironment
Authors: Zaynagetdinov Rinat , Sherrill Taylor P. , Gleaves Linda A. , McLoed Allyson G. , Saxon Jamie A. , Habermann Arun C. , Connelly Linda , Dulek Daniel , Peebles R. Stokes , Fingleton Barbara , Yull Fiona E. , Stathopoulos Georgios T. , Blackwell Timothy S.
Published: March 2023

Figure S2. Deficiency in IL-5 does not affect infiltration of lungs with T and B lymphocytes and NK cells during initial stages of metastatic load of LLC cells.
Supplementary Figure 6 from IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Authors: Caetano Mauricio S. , Zhang Huiyuan , Cumpian Amber M. , Gong Lei , Unver Nese , Ostrin Edwin J. , Daliri Soudabeh , Chang Seon Hee , Ochoa Cesar E. , Hanash Samir , Behrens Carmen , Wistuba Ignacio I. , Sternberg Cinthya , Kadara Humam , Ferreira Carlos Gil , Watowich Stephanie S. , Moghaddam Seyed Javad
Published: March 2023

Supplementary Figure 6. Increased levels of IL-6 in bronchoalveolar lavage fluid (BALF) of CC-LR mice after NTHi exposure.
Supplementary Figure 4 from IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Authors: Caetano Mauricio S. , Zhang Huiyuan , Cumpian Amber M. , Gong Lei , Unver Nese , Ostrin Edwin J. , Daliri Soudabeh , Chang Seon Hee , Ochoa Cesar E. , Hanash Samir , Behrens Carmen , Wistuba Ignacio I. , Sternberg Cinthya , Kadara Humam , Ferreira Carlos Gil , Watowich Stephanie S. , Moghaddam Seyed Javad
Published: March 2023

Supplementary Figure 4. Lung lesion distribution in lungs of CC-LR mice.
Supplementary Figure 3 from IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Authors: Caetano Mauricio S. , Zhang Huiyuan , Cumpian Amber M. , Gong Lei , Unver Nese , Ostrin Edwin J. , Daliri Soudabeh , Chang Seon Hee , Ochoa Cesar E. , Hanash Samir , Behrens Carmen , Wistuba Ignacio I. , Sternberg Cinthya , Kadara Humam , Ferreira Carlos Gil , Watowich Stephanie S. , Moghaddam Seyed Javad
Published: March 2023

Supplementary Figure 3. Increased levels of IL-6 in bronchoalveolar lavage fluid (BALF) of CC-LR mice during tumor progression.
Table S2. Gene Set Enrichment Analysis (GSEA) C5 GO gene sets. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma
Authors: Ravi Dashnamoorthy , Beheshti Afshin , Abermil Nasséra , Passero Frank , Sharma Jaya , Coyle Michael , Kritharis Athena , Kandela Irawati , Hlatky Lynn , Sitkovsky Michail V. , Mazar Andrew , Gartenhaus Ronald B. , Evens Andrew M.
Published: March 2023

Complete list of GSEA for C5 GO gene sets in the ixazomib 25nM/24 hours vs. Control for Jurkat, L428, and L540 cells. Leading edge analysis with a FDR {less than or equal to} 0.05 determined significant gene sets enriched for each group. The normalized enrichment score (NES) indicates whether the gene set is up- (>0) or down-regulated (<0) for each group determined with the # of leading edge genes (appears in parenthesis).
Supplemetary Video S8 from Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis
Authors: Stanisavljevic Jelena , Loubat-Casanovas Jordina , Herrera Mercedes , Luque Tomás , Peña Raúl , Lluch Ana , Albanell Joan , Bonilla Félix , Rovira Ana , Peña Cristina , Navajas Daniel , Rojo Federico , García de Herreros Antonio , Baulida Josep
Published: March 2023

Video S8. Ela-Myc cells on 3D-ECM generated by TGFÃŽÂ²-treated KO MEFs.
Supplemental Table 2 from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: March 2023

Supplemental Table 2. This data provides transcriptomic analysis of the ZMEL1 line (RNA-seq) along with GSEA analysis comparing ZMEL1 to either human melanomas or primary zebrafish transgenic melanomas.
Supplemental Methods from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: March 2023

This file provides additional information on reagents and software analysis of images.