bluuebunny/crossref_metadata_2025 huggingface dataset:
Education and education with values in the face of contemporary challenges
Authors: Rola Beata , Rola Jarosław
Published: July 2024

The current reality, with its multidimensionality and challenges related to the increasingly experienced diversity, affects the sense of stability and security among children and adolescents. Assuming that school is a place where every student has a chance to develop adaptive skills, it is this environment that should provide high-quality role models as well as a focus on stable values that will build social sensitivity and mental strength of students. In this text, we present practical solutions on how to explore the essence of values and at the same time put them into practice. We encourage educators, teachers and caregivers to consider education with values as a way to develop in students a certain philosophy of life that supports their maturation, full development and decisions, and thus fosters inclusion in the community with respect, trust and a sense of meaning. The material contains a theoretical part referring to the assumptions of positive psychology and several ideas, such as exercises on implementing key values.
ANALISIS DE LA TASA DE EGRESO DE LAS CARRERAS DE INGENIERÍA EN LA FACULTAD DE CIENCIAS Y TECNOLOGÍAS (FCYT) DE LA UNIVERSIDAD NACIONAL DE CAAGUAZU (UNCA)
Authors: Estigarribia Barreto Héctor Ramiro , Alfredo Recalde Hugo
Published: July 2024

La importancia de la formación de ingenieros es destacada a nivel global, con múltiples publicaciones y agencias gubernamentales resaltando la necesidad de aumentar su cantidad como estrategia para fortalecer el desarrollo nacional. En Paraguay, a pesar de que se habla mucho de una brecha significativa entre la cantidad de ingenieros egresados y la necesidad del mercado, no existen datos actualizados y verificables sobre el tema, más allá de algunas declaraciones en medios de prensa. El objetivo de la presente investigación fue analizar la tasa de egreso y otros datos relacionados a las carreras de ingeniería de la Facultad de Ciencias y Tecnologías de la Universidad Nacional de Caaguazú (FCyT UNCA) estudiados hasta el 2023, actualizar los datos y poder analizar la evolución de estos, luego de ciertos hechos históricos tales como la pandemia del COVID-19 y los cambios que se implementaron en la institución teniendo como referencia un estudio anterior que informaba de una tasa egreso real del 10% hasta el 2020. Para obtener los datos actualizados se aplicó la técnica propuesta por López Suarez y otros (2007), que consiste en elaborar una base de datos en la cual se individualiza cada egresado de la institución en estudio y se registran los años de carrera desde que ingresa hasta que egresa. La institución analizada es de apenas 14 años de historia que empezó a producir egresados a partir del 2016 por lo que existen 14 cohortes de ingresantes y 8 de egresados. Un hallazgo importante es que la tasa de egreso real total hasta ahora de la FCyT UNCA es del 15%, pero con una tasa esperada basada en los rendimientos de las cohortes que tienen mayor cantidad de egresados es de 30%, que no se encuentra lejos de las cifras que los pocos artículos de la región disponibles sobre el tema dan cuenta.
POESIA VISUAL EM MEIOS DIGITAIS: UMA ABORDAGEM PARA A FORMAÇÃO DE LEITORES NO CONTEXTO ESCOLAR
Authors: Marrafão Jaqueline Araujo Esteves , Magalhães Epaminondas de Matos
Published: July 2024

Formar leitores não é uma tarefa fácil, principalmente quando se faz uma reflexão sobre o cenário educacional atual. Práticas inovadoras educacionais devem estar inseridas nos planejamentos das aulas. A formação de leitores literários vai além da simples capacidade de ler frases e textos, ela abrange a capacidade de compreensão do que está nas entrelinhas. Ou seja, de inferir sentidos ao que está lendo. Atualmente, utilizar recursos tecnológicos em sala de aula, nas leituras literárias, possibilita a capacidade de leitura de distintos gêneros literários. Este artigo buscará discutir a formação de leitores no contexto escolar atual a partir de poesias visuais em plataformas digitais e a prática docente, nesta transposição didática. Para tal discussão, utilizar-se-á como aporte teórico Aguiar (2011), Cosson (2022) e Sorrenti (2009) entre outros autores que poderão contribuir para a reflexão. Logo, pretende-se promover uma reflexão sobre a formação do leitor literário por meio da leitura das poesias visuais em meios digitais no contexto escolar.
HOMILADORLIK FONIDA RIVOJLANGAN GESTATSION PYELONEFRITINING PATOMORFOLOGIK JIHATLARI
Authors: Tojiboev Temurbek , Mamataliyeva Madina
Published: July 2024

Pielonefrit homilador ayollarda eng ko'p uchraydigan buyrak kasalliklaridan biridir. Homiladorlik pyelonefritining etiologiyasida opportunistik mikroorganizmlar ustunlik qiladi (asosan enterobakteriyalar va enterokokklar (23%)). Surunkali pielonefritning takrorlanishi bilan homiladorlik ko'pincha preeklampsi bilan murakkablashadi va yangi tug'ilgan chaqaloqlarda yuqumli va yallig'lanish kasalliklarini rivojlanishi xavfi ortadi. Pielonefrit muammosining dolzarbligi xomila va xomilador onada yuqumli va septik asoratlarning mavjudligi va uni homiladorlik paytida yuzaga keladigan yuqori siydik yo’llarining kengayishiga salbiy ta’sir ko’rsatishida-dir. Homiladorlikning rivojlanishi pielonefritning surunkali kechishinii rivojlantiradi, buyrak kolikasining tez-tez hurujlariga olib keladi, buyrak etishmovchiligini keltirib chiqaradi.
ERTA YOSHLI BOLALARDA BRONXOOBSTRUKTIV SINDROM KECHISHI VA XAVF OMILLARI
Authors: Turaqulova Hilola
Published: July 2024

So'nggi yillarda shifokorlar mehnat faoliyati davomida bronxial obstruktsiya kabi holatlarga ko'proq duch kelishmoqda. Erta yoshli bolalarda bronxo-obstruktiv sindromning (BOS) paydo bo'lishi va rivojlanishiga turli omillar ta'sir ko'rsatadi. Tadqiqot maqsadi: Erta yoshli bolalarda bronxoobstruksiyani kechishi va xavf omillarini aniqlash. Materiallar va usullar. Tadqiqot Andijon viloyati bоlalar ko’p tarmoqli tibbiyot markazi Pulmonologiya bo’limida va Respublika ixtisoslashtirilgan Pediatriya ilmiy amaliy tibbiyot markazi Pulmonologiya bo’limida o’tkazildi.  Biz 1 yoshdan 15 yoshgacha bo'lgan 120 nafar bolani kuzatdik. Nazorat guruhi xuddi shu yoshdagi 20 nafar sog'lom bolalardan iborat edi.Natijalar va uning muhokamasi. 1 yoshdan 15 yoshgacha bo'lgan bolalar tekshiruvdan o'tkazildi. Bolalarning yoshi bo‘yicha taqsimlanishi shuni ko‘rsatdiki, shifoxonadan tashqari zotiljam obstruktiv sindrom bilan ko‘proq 1-3 yoshli bolalarda 48 (63%), 4-6 yoshli bolalarda 17 (23%), 7-11 yosh 9 (12) yoshda. %), 12-18 yoshli bolalarda esa 2(2%) ni tashkil qildi. Tekshirilayotgan bemorlarda kasallikning og'irligiga noqulay premorbid fon va birga keladigan patologiya sezilarli darajada ta'sir qiladi. Xulosa. Erta yoshli bolalarda bronxoobstruktiv sindrom 1 yoshdan 3 yoshgacha bo'lgan yosh oralig'ida ko'proq uchraydi, rahitning qoldiq belgilari, kamqonlik, allergik anamnezning bo’lishi va oqsil-energiya yetishmovchiligi kabi bir qator hamroh kasallilarni, shuningdek ularning kombinatsiyasi bronxoobstruktiv sindrom rivojlanishi uchun xavf guruhiga kiritilishi kerak.
Design and validation of an instrument to measure e-governance through factor analysis
Authors: Páez Moreno Ángel Emiro , Parra Fonseca Carolina
Published: July 2024

E-governance combines the use of electronic means in interaction between government and citizens, government and business, and within government operations to enhance democratic, governmental, and business aspects of governance. Thus, e-governance is built on a paradigmatic dimension such as e-democracy (relationship between government and citizens) and an operational dimension such as e-governance. The objective was to design and validate an instrument to measure e-governance based on three factors: a) e-administration, b) e-services, and c) e-democracy.Method: based on the level of importance given to each factor (sample of 2042 Latin American citizens), as well as the relationships between them, an analysis of the importance of each factor is carried out.Results: after the confirmatory analysis, the definitive instrument with which e-governance can be measured by other researchers and future research is obtained, considering the three selection factors, namely: e-administration, e-services and e-democracy.Conclusions: this research contributes to political science through the design and validation of an instrument consisting of 39 items that can be used to measure e-governance according to the dimensions proposed by the United Nations Educational, Scientific and Cultural Organization
Application of the ARAS Method in Risk Assessment and Mitigation in IVF Procedures
Authors: Ramos Velastegui Alexander Javier , Guato Canchinia Diego Eduardo , Maldonado Mariño Edisson Vladimir
Published: July 2024

In vitro fertilization (IVF) is an assisted reproduction technique that has enabled many couples to achieve parenthood. Despite its benefits, IVF treatments carry risks and complications that can impact the mother's health and the success of the pregnancy, making a systematic evaluation of safety essential. This study applies the ARAS method to identify and mitigate the main risks associated with IVF, using criteria such as severity, frequency, impact on pregnancy, and recoverability. Among these, implantation failures and spontaneous abortions were identified as the most significant risks, followed by ovarian hyperstimulation syndrome (OHSS). To reduce these risks, an improvement and monitoring plan for IVF treatments is proposed, focused on optimizing safety and effectiveness. It includes advanced monitoring, continuous training, and regular evaluations to adapt practices to the latest research and technologies. Furthermore, the findings suggest that a personalized and evidence-based approach can significantly increase the safety of IVF treatments. Additionally, the importance of considering both medical and psychosocial factors to enhance patient experience and outcomes is emphasized. In conclusion, this study provides a solid foundation for future improvements in IVF practices, ensuring that procedures are performed in the safest and most effective manner possible.
The Future of Healthcare: Evaluating the Impact of Emerging Technologies on Medical Care
Authors: Donoso Noroña Riber Fabián , Gómez Martínez Nairovys , Rodríguez Plascencia Adisnay
Published: July 2024

Telemedicine has proven particularly valuable in improving access to care for patients in remote areas by enabling medical consultations without the need for travel. However, the adoption of these technologies faces significant challenges, especially in terms of ethics and privacy, which requires the development of robust policies to protect patient data and ensure equitable access. Therefore, this study aims to investigate and analyze emerging technologies such as telemedicine, artificial intelligence (AI), and robotics in the transformation of healthcare. To this end, the impact on efficiency, accessibility, and the quality of care, as well as future implications in remote medicine, has been analyzed. Through the analysis of research materials and methods, the acceptance of these technologies by patients and health professionals was evaluated, where improvements in diagnostics and the optimization of surgical procedures with greater precision and less invasiveness have been valued. Furthermore, the results suggest that although telemedicine, AI, and robotics offer substantial benefits, successful implementation requires considering the needs and concerns of all users. In conclusion, it is crucial to continue the development of policies and technological innovation to maximize the benefits and ensure the safe and effective implementation of these technologies in healthcare.
New perspectives in the treatment of heart failure: The role of SGLT2 inhibitors
Authors: Donoso Noroña Riber Fabián , Gómez Martínez Nairovys , Rodríguez Plasencia Adisnay
Published: July 2024

Heart failure (HF) has been a prevalent chronic disease globally and one of the main causes of mortality historically. A recent study assessed the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) on the management of HF. It focused on improving health outcomes and the quality of life of patients. The methodology included a systematic review of clinical and observational trials that compared SGLT2 inhibitors with standard treatments and placebos. The efficacy of SGLT2 inhibitors was examined across various patient subgroups, taking into account variables such as renal and cardiovascular function, vascular resistance, and neurohormonal mechanisms. The results showed that SGLT2 inhibitors significantly improved cardiac and renal function. They also reduced mortality and hospitalizations associated with HF. These benefits were observed in both patients with type 2 diabetes and those without this condition. In conclusion, the study confirmed that SGLT2 inhibitors are a valuable therapeutic option for patients with HF. It highlighted the need to include them in treatment strategies and emphasized the importance of expanding research to better understand the mechanisms, efficacy, and safety of SGLT2 inhibitors in HF, thereby guiding future health policies.
Arterial hypertension: a global public health challenge and the need for comprehensive strategies
Authors: Jiménez Jiménez Mayra Jeaneth , Aveiga Hidalgo María Verónica , Bustos Villarreal Mónica Alexandra
Published: July 2024

High blood pressure affects more than 1 billion people and is one of the main causes of morbidity and mortality. This chronic condition, often asymptomatic in its early stages, can lead to serious cardiovascular diseases if not managed properly. Its risk factors include modifiable elements such as obesity and a sedentary lifestyle, as well as non-modifiable factors such as genetics and age. Effective management of hypertension requires timely diagnosis, medical treatment, and significant lifestyle changes. The present study aims to develop educational strategies to reduce complications. Through a qualitative-quantitative approach with the development of a survey, it was learned that the majority of patients do not have knowledge about their disease, are sedentary and do not follow an adequate diet, nor do they engage in physical activity. It is concluded to propose education strategies that promote healthy environments on hypertension to mitigate its global impact and thus improve quality of life and reduce the economic burden on health systems.
Prevalence of caffeine-dependent students in the electromechanical engineering program at Universidad Technical Equinoctial
Authors: Ezcurdia Barzaga Manuel Conrado , Diaz Cruz Ronny Steeven , Suarez Jaramillo Estefanny Sulay , Villacis Defaz Alexis Saul
Published: July 2024

Caffeine consumption is a common practice among university students to cope with academic demands. This study aimed to determine the prevalence of caffeine-dependent students in the Electromechanical Engineering program at the Technical University Equinoccial of Ecuador. A non-experimental and descriptive design was used. Surveys were conducted with 156 students to assess their caffeine consumption habits, product preferences, and knowledge of its effects. The results indicated that 40,4 % of the students consume caffeine daily, and 84,6 % have a low level of knowledge about its consequences. The prevalence of consumption was higher among men, although women showed a higher tendency in percentage terms. The study concludes the need to implement educational and awareness strategies on responsible caffeine consumption and its health risks, and thus an educational and preventive proposal is made to the institution subject of this study.
Clinical case of treatment of anterior open bite malocclusion in a pediatric patient using a tongue trap
Authors: Urrego Cueva Gladys Viviana , Díaz Espinoza German , Ibarra Ramírez María Belén
Published: July 2024

Anterior open bite is a complex and multifactorial malocclusion that affects both dental function and aesthetics. The objective of the study was to present a clinical case of anterior open bite (AOB) treatment in a pediatric patient using a lingual trap. A case study was conducted on a 7-year-old girl with AOB, employing a removable orthopedic appliance. The treatment consisted of using a lingual trap to correct the open bite and promote proper mandibular growth, with monthly check-ups and a total duration of 12 months. The results showed a significant improvement in occlusion and dental alignment, as well as in the facial profile. It is concluded that the lingual trap is an effective tool in the treatment of anterior open bite in pediatric patients, highlighting the importance of an integral and personalized approach to achieve successful results.
Semiotic field of directing at the beginning of the XXI century
Authors: Krypchuk Mykola , Nabokov Roman , Rozhkovska Viktoriia , Chepura Kateryna , Sukhomlyn Hanna
Published: July 2024

We live in a time of amazing and astounding achievements in scientific and artistic thought. More and more new technologies are being developed in various fields, including information. Today it has become a common occurrence, and no one is surprised by the breadth and variety of forms of information transmission, the main tool of which are nothing but signs. We often perceive the meaning of signs as directly as we see images, hear sounds, smells, etc., in science this is called semiotics – a theory that explores the system of signs. The purpose of the study was to study the application of the sign system in art, namely in the field of directing at the present stage. The leading method of research was structural-semiotic analysis, with the help of which modern cinema was analysed for the use of semiotic means in it. In the course of the research, it was found that semiotics is inextricably linked with art, since the creators of their works often use signs and hidden symbols in creativity, thus giving the recipient the opportunity to independently interpret what he saw or heard. The field of directing is also no exception, most of them are theatrical productions and cinematic works. In cinema, the system of signs has become widespread, and a set of certain symbols is a distinctive feature of some directors. The research contributes to the development of the problems of using sign systems in various fields of activity, which expresses its practical significance
Economic evolution of Durres University: A historical perspective from 1803 to 2030
Authors: Shahini Ermir
Published: July 2024

The purpose of this study was to examine the history of the development of Alexander Moisiu University of Durres to form recommendations for its future development. It also remained important to form advices in the context of the future development of universities to ensure the improvement of the entire field of education. The main methods that were used in the framework of the study were analysis, forecasting, and comparison. The paper considered the features of the development of the city of Durres, its role for the country, and the main areas of activity. Subsequently, the history of the main local Alexander Moisiu University, which was founded in 2006, was evaluated. It was concluded that, despite significant successes, there are still difficulties and problems in its development. In this regard, actions were proposed (from the standpoint of the university’s management staff) to improve the quality of the university’s development in the future. Special attention was paid to components of innovation, digitalisation, and sustainable development. The conclusions showed that close cooperation between the municipality and the university will lead to mutually beneficial consequences, which is why representatives of both sides should be interested in this. The conclusions generated within the framework of the study can be used both to develop the future strategy of Alexander Moisiu University and to form a state strategy in the field of education in general
Prevalensi Pediculosis di Kelurahan Bandar Lor Kecamatan Mojoroto Kota Kediri
Authors: Wahyuni Ismiy , Rihi Dida Leonardus , Saidi Viedya
Published: July 2024

Pediculus humanus capitis sering ditemukan di daerah padat penduduk yang kurang memperhatikan kebersihan lingkungan. Penelitian ini dilakukan di Gang 1 A Kelurahan Bandar Lor Kota Kediri yang padat penduduk dan bertujuan mengetahui hasil identifikasi parasit Pediculus humanus capitis serta untuk mengetahui morfologi parasit Pediculus humanus capitis. Jenis penelitian yang digunakan adalah penelitian deskriptif dengan  desain penelitian cross sectional serta menggunakan teknik Acidental sampling. Jumlah sampel yang digunakan adalah 30 sampel. Dari hasil penelitian yang sudah dilakukan masih banyak warga  yang belum menerapkan personal hygiene dengan baik contohnya dari kebersihan rambut, kebersihan pakaian dan juga kebersihan lingkungan sekitar dan  hasil penelitian menunjukan bahwa pada kelompok responden dengan hunian yang padat memiliki persentase 20,44% positif Pediculus humanus capitis dibandingkan dengan yang negativ dengan persentase 11,30%  Pediculus humanus capitis dapat menyebar dengan cepat di lingkungan hidup yang padat. Dari hasil penelitian pada warga  gang 1A kelurahan Bandar Lor Kota Kediri ditemukan  20 Sampel positif Pediculus humanus capitis (67%) dan 10 sampel negatif Pediculus humanus capitis (33%). Diharapkan peneliti selanjutnya bisa mengembangkan penelitian mengenai Pediculus humanus capitis misalnya menganalisis hubungan antar aktivitas fisik dengan kejadian infeksi Pediculus humanus capitis.
el-MELİKÜ’L-EŞREF SEYFEDDİN BARSBAY (1422-1438)’IN KIBRIS SEFERLERİ
Authors: Canbolat Hatice
Published: July 2024

Bu çalışmamızda ilk olarak Lusignanlar’ın yaklaşık üç yüzyıl sürecek olan hanedanlıklarının kuruluş sürecine zemin hazırlayan dönem aralığı, Kıbrıs adasının Haçlı-Bizans birlikteliğinde üstlendiği rollerini ele alıp bir temel oluşturduktan sonra asıl konumuzu teşkil eden Barsbay’ın Kıbrıs’a düzenlediği üç sefer üzerinde duracağız. Lusignan Kralları’ndan Janus dönemine denk gelen Kıbrıs seferleri 827\1424, 828\1425 ve 829\1426’da yıllarında vuku bulmuştur. Bunların ilki keşif mahiyetinde küçük bir sefer olsa da son ikisinde sadece adanın kıyı kesimleriyle kalınmamış iç kısımlarına da nüfuz edilmiş hatta o devirde Kıbrıs’a başkentlik yapan Afkosiye (Nicosia\Lefkoşe) de Emir Tağriberdi el-Mahmudî ve mahiyetindeki askerler tarafından ele geçirilmiştir.
Haçlıların 1291’de Akka’yı kaybetmeleri neticesinde Kıbrıs’taki Lusignanlara sığınmaları, Akdeniz’de ekonomik ve siyasal girişimlerde boy göstermeleri, özellikle 1365’teki İskenderiye saldırısı ve korsancılık faaliyetlerinde adlarından söz ettirmeleri Kıbrıs-Memlük ilişkilerini farklı bir noktaya taşımıştır. Bu da Akdeniz’de bir güç mücadelesine kapı aralamış, nihayetinde de ada Memlüklerin hakimiyeti altına girmiştir. Barsbay-Janus ilişkisini dönem kaynaklarında yıllar ve aylar bazında kayıt tutan tarihçilerden ve bunlar içinde yer almakla birlikte Bedreddin Aynî ve İbn Hacer gibi sefere özgü başlıklar açıp spesifik olarak konuyu ele alan müelliflerimizden faydalanarak sunmaya gayret gösterdik.
Marketing Strategical Analysis of Products UMKM Markets with Tol
Authors: Nasution Muhammad Iqbal , Nasution Muhammad Syukri Albani , Rahmani Nur Ahmadi Bi
Published: July 2024

Marketing Strategy is a way for UMKM players to introduce their products to the wider community in order to achieve the desired vision and mission. The aim of this research is to find out what marketing strategies business actors use to maintain income stability in accordance with the 4Ps. This research is descriptive qualitative research. The data collection methods used in this research are interviews and observation. The results of this research show that 1) Every UMKM actor in the workshop market, if they want to be better known for their products, they can use methods such as the program carried out by the Industry and Trade Department, where they take advantage of festivals or other important celebrations to advance regional businesses. and it was proven that they could reap profits from the event from selling food alone which was around ± Rp. 3,000,000 million in two days. 2). UMKM players can also rearrange the composition of the materials usually used or pay attention to the quality of the raw materials so that the product results are better than before.
Application of fulvic acid and potassium fertilization to reduce the harmful effect of salt water stress on growth, productivity and nutritional status of tomato plants
Authors: El-Rheem Kh. M. Abd , S. H. Mahmoud  , El-Tanahy A.M.M.
Published: July 2024

Water is a key resource for sustainable agricultural development in Egypt. The scarcity of fresh water resources in Egypt has led to the use of salt water for irrigation. Therefore, the aim of the research was to study the effect of potassium fertilization and spraying with fulvic acid on tomato plants irrigated with salt water and grown in sandy soil during two successive growing seasons. Different rates of the potassium fertilization combined with different concentrations of fulvic acid foliar application. The rates of K fertilization were 150, 200 and 300 Kg K2O per hectare of the recommended fertilizer unit (300 kg K2O ha-1). While, the concentrations of fulvic acid were 500, 1000 and 2000 mgl-1. Increasing the spraying concentration of fulvic acid from 500 to 2000 ppm resulted in a significant improvement in the parameters of growth, quantity and quality yield of tomato plants with an increase in potassium fertilization rates from 150 to 300 K2O kg ha-1with the use of saline irrigation water. Increasing the concentration of fulvic acid spraying led to the uptake of nitrogen, phosphorus and potassium in tomato leaves increased with an increase in potassium fertilization rates.Therefore, it can be said that spraying fulvic acid with the use of potassium fertilization is one of the successful solutions in reducing the effect of irrigation with salt water on the growth and yield of tomato plants.
Post-MI cardiac repair: The role of angiogenesis in heart rejuvenation –Areview
Authors: Ramesh Nishanth , Sarkar Mayukh , Gurung Pravash , Gurung Sushil , Chettri Rohit , Honnegowda Chandini , Samanta Sairashmi
Published: July 2024

After a myocardial infarction (MI), the heart's limited regenerative capacity is outstripped by substantial myocytes degeneration and significant arterial damage. Cardiac repair involves a complex, well-coordinated sequence of events, including a strong angiogenic response in the heart's peri-infarct border zone, leading to fibroblast proliferation and scar formation. Effective vascular formation post-MI helps limit myocytes hypertrophy and reduces scar formation by decreasing collagen deposition, thus improving heart function. Robust data from conventional in vitro thrombotic approaches and animal models show that multiple synchronized signaling pathways, including Wnt, PI3K, Notch, and ion channel regulation of cytoplasmic Ca2+levels, control angiogenesis of endothelial precursor cells (EPCs) and existing endothelial cells (ECs). Factors like hypoxia, VEGF and FGF family growth factors, nitric oxide synthase, inflammation, and miRNAs are crucial in angiogenic pathways, significantly impacting the infarcted heart. Post-MI, paracrine and autocrine cell-to-cell signals, predominantly delivered by extracellular vesicles carrying pro-angiogenic proteins and non-coding RNAs like miRNAs, are vital for cardiac repair. This review overviews major angiogenic pathways and their effects on post-infarction myocardial angiogenesis, emphasizing the roles of endothelial nitric oxide synthase and growth factors like VEGF and FGF. It also explores signaling pathways triggered by MI, focusing on ROS regulation, Ca2+influx, and miRNAs in endothelial cell activation and subsequent angiogenesis. Additionally, the review discusses troponin's role as a biomarker for myocardial infarction, highlighting its function as a potent angiogenesis inhibitor.
Antibacterial Activity of Piper betle Leaf Extract Mediated MnO2 Nanoparticles
Authors: Subramanian P. , David S. Alwin
Published: July 2024

The biogenesis of manganese dioxide nanoparticles using Piper betle leaf extract is explained in this work as a simple, environment friendly and effective process. Using Piper betle leaf extract as a reducing agent, potassium permanganate was reduced to synthesize the MnO2 NPs. The contribution of the biomolecules in the Piper betle leaf extract to the production of MnO2 NPs was revealed by Fourier-transform infrared spectra. The biosynthesized MnO2 NPs' UV–visible spectra showed absorption peaks around 271 nm, which is the MnO2 NPs' absorption maxima. According to the scanning electron microscopy study, the 70–80 nm-sized biosynthesized MnO2 NPs exhibit an irregular form. The presence of Mn and O in the MnO2 NPs was verified by EDAX. MnO2 NPs were tested for their antibacterial properties against Bacillus subtilis, Bacillus cereus, and Bacillus amyloliquefaciens. The antibacterial activity of the biosynthesized MnO2 NPs is mild.
Análisis in situ en una cantera-taller de dacitas vítreas, Región de Antofagasta, Puna de Atacama, Chile
Authors: Baeza de la Fuente Verónica
Published: July 2024

Se presenta la investigación desarrollada en una cantera-taller de dacitas vítreas emplazada en los faldeos del volcán Toconce, en la puna de Atacama, lugar que abasteció de esta materia prima a varios sitios de la cuenca del río Salado, principalmente durante el Arcaico Tardío y el Formativo Temprano. El trabajo consistió en un análisis in situ del material lítico, metodología adecuada para el manejo de áreas de cantera-taller con grandes volúmenes de material y dificultades en el acceso, entre otros factores. Se muestran la metodología y los resultados y se evalúa el funcionamiento interno de la fuente, así como las relaciones regionales con otros sitios arqueológicos, dado su emplazamiento en la ruta entre el alto río Loa, el río Salado y el altiplano de Lípez. Se analizan las metodologías desarrolladas y la muestra trabajada. Como conclusión, se plantea el análisis in situ como una metodología válida para el registro de materiales líticos en áreas de aprovisionamiento.
Hekimlerin Hastalarına İlişkin Sosyal Medya Paylaşımlarından Doğan Sorumluluğu
Authors: Çavdar Pelin
Published: July 2024

Sosyal medya kullanımı sağlık sektöründe de son yıllarda oldukça yaygınlaşmaya başlamıştır. Hekimler daha çok hastaya ulaşmak ve kendi başarılarını göstermek amacıyla hastalarına ilişkin sosyal medyada paylaşımlar yapmaktadır. Bu paylaşımlarda esas alınması gereken ilkelere ilişkin 2016 yılında Türk Tabipler Birliği tarafından Hekimler ile Sağlık Kurum ve Kuruluşlarının Elektronik Ortamlardaki Paylaşımlarına İlişkin Kılavuz yayımlanmıştır. Bu Kılavuz dışında, en güncel yasal düzenleme 2023 yılında yürürlüğe giren Sağlık Hizmetlerinde Tanıtım ve Bilgilendirme Faaliyetlerine İlişkin Yönetmeliktir. Hekimler hastalarına ilişkin yapmış olduğu sosyal medya paylaşımlarında hastanın özel hayatının gizliliğine saygı göstermeli, hasta mahremiyetinin ve hastanın kişisel sağlık verilerinin korunmasına ilişkin kurallara riayet etmelidir. Bunların dışında hekimlerin hastalarına ilişkin sosyal medya paylaşımları hukuka aykırı reklam niteliğinde olmamalıdır. Hekimlerin hastalarına ilişkin sosyal medya paylaşımları belirlenen kurallara aykırı olduğu takdirde, hastanın TMK’da düzenlenen koruyucu davaları ve tazminat davası açması mümkündür. Bunların dışında Kişisel Verileri Koruma Kanunu çerçevesinde talepte bulunabilir. Ayrıca, hekimlerin TTB tarafından uygulanacak mesleki disiplin yaptırımı, idari para cezası ve Reklam Kurulu tarafından yürütülecek inceleme sonucunda çeşitli uygulamalarla karşılaşması da mümkündür.
The Significance of the Language Laboratory for Arabic Non-Native Speakers in the Arabic Teaching Institutes of Sri Lanka
Authors: Mohamed Thalib
Published: July 2024

In Sri Lanka, where Arabic is not a native language, the Establishment of Arabic language laboratories presents significant opportunities for enhancing linguistical proficiency among non-native speakers.  This study aims to explore the impact of Arabic language laboratories on language proficiency and cultural understanding among non-native speakers in the Arabic teaching institutes of Sri Lanka and evaluate the effectiveness of technological tools in Arabic language laboratories for facilitating language acquisition among non-native speakers in the Arabic teaching institutes of Sri Lanka. This study concluded that Establishing Arabic language labs in the Arabic teaching institutes of Sri Lanka is a strategic investment, offering diverse benefits beyond linguistic proficiency. These labs foster cultural awareness and open avenues for academic and professional growth. Recommendations include investing in technology, updating the curriculum to reflect linguistic and cultural trends, and providing teacher training. Cultural immersion programs and ongoing research are also crucial. Collaboration with international partners and promoting Arabic learning are essential for enriching educational experiences and fostering a globally competitive workforce.
Konsep Media Pembelajaran Menyimak di Kelas Tinggi
Authors: Bintang Mahrani Abdullah  , Miftahul Jannah  , Yunita Azhari  , Juni Sahla Nasution
Published: July 2024

Listening learning media in higher classes is an intermediary tool that makes it easier for students to focus on understanding learning material. This research aims to determine the concept of listening learning media in high school. This research method uses qualitative methods based on literature study. Literature study is a method that collects various sources to be used as references. The results of this research show that there are still many students who are less serious about understanding the learning material. Therefore, listening learning media is very important to use in the learning process. Because, using listening learning media can make it easier for students to focus on understanding the meaning of the learning they are listening to and can make learning more interesting and not boring.
Desafío pedagógico de los nuevos registros de grado: valoración de docentes en primaria y secundaria
Authors: Durán Ángel Luis
Published: July 2024

La llegada a los centros educativos de los nuevos registros de grado resultó un desafío para los docentes ya que los mismos, trajeron consigo una modalidad de trabajo que necesitó más desempeño y entrega por parte de los maestros y maestras del sistema educativo dominicano. En tal orden, el objetivo de este estudio fue determinar qué incidencias de los nuevos registros de grado, provocaron dificultades en las labores docentes en el nivel primario y secundario. Este estudio, contó con la escogencia de forma conveniente de 15 docentes del centro educativo Carlos Díaz, perteneciente al distrito 08-09 de Tamboril. La metodología respondió a un estudio cualitativo descriptivo de tipo no experimental puesto que, recolectó las opiniones de los docentes de forma descriptiva, pero sin las intenciones de alterar las mismas. Para la recolección de tales datos se utilizaron las técnicas de grupos focales y entrevista mientras que, el instrumento fue el cuestionario con el cual, se pudieron registrar de forma cualitativa las opiniones de cada docente que se analizaron por medio de distintas tablas concluyendo que, los docentes tienen un compromiso educativo y social por el cual, deben asumir de forma responsable y eficiente sus tareas labores, sin embargo, es menester de las autoridades elaborar registros más asequibles a las realidades puesto que, los mismos deben llegar a tiempo y no requerir, que se registre una excesiva cantidad de información que provoca fatiga y ciertos errores en el trabajo de los docentes.
Kidney transplantation access and outcomes for Aboriginal and Torres Strait Islander children and young adults, 1963–2020: an ANZDATA registry study
Authors: Chaturvedi Swasti , Ullah Shahid , Hughes (Wagadagam) Jaquelyne T
Published: July 2024

Objectives

To assess differences between Aboriginal and Torres Strait Islander and non‐Indigenous Australian children and young adults in access to and outcomes of kidney transplantation.

Study design

A cohort study based on prospectively collected data; analysis of Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) data.

Setting, participants

Children and young adults aged 0–24 years who commenced kidney replacement therapy in Australia during 1963–2020.

Main outcome measures

Proportions of children and young adults who received kidney transplants within five years of commencing dialysis; 5‐ and 10‐year death‐censored graft survival; and 5‐ and 10‐year survival of children and young adults who received kidney transplants or who remained on dialysis.

Results

During 1963–2020, 3736 children and young adults received kidney replacement therapy in Australia: 213 (5.8%) Aboriginal and Torres Strait Islander and 3523 (94.2%) non‐Indigenous children and young adults. During follow‐up (median, eight years; interquartile range [IQR], 2.6–15 years), 2762 children and young adults received kidney transplants: 93 Aboriginal and Torres Strait Islander (43.7% of those receiving kidney replacement therapy) and 2669 non‐Indigenous children and young adults (75.8%). Smaller proportions of Aboriginal and Torres Strait Islander than of non‐Indigenous children and young adults received transplants within five years of commencing dialysis (99, 46% v 2924, 83.0%), received living donor transplants (19, 20% v 1170, 43.9%), or underwent pre‐emptive transplantation (one, 1.1% v 363, 13.6%). Five‐year graft survival for Aboriginal and Torres Strait Islander recipients was similar to non‐Indigenous recipients (61% v 75%; adjusted hazard ratio [aHR], 1.43; 95% confidence interval [CI], 0.02–2.05), but 10‐year graft survival was lower (35% v 61%; aHR, 1.69; 95% CI, 1.25–2.28). Five‐ and 10‐year survival after kidney transplantation was similar for Aboriginal and Torres Strait Islander and non‐Indigenous people. Among those who remained on dialysis, 10‐year survival was poorer for Aboriginal and Torres Strait Islander than non‐Indigenous children and young adults (aHR, 1.50; 95% CI, 1.08–2.10).

Conclusions

Five‐year graft and recipient survival were excellent for Aboriginal and Torres Strait Islander children and young adults who received kidney transplants; however, a lower proportion received transplants within five years of dialysis initiation, than non‐Indigenous children and young adults. Improving transplant access within five years of dialysis commencement should be a priority.
Knowledge translation in Indigenous health research: voices from the field
Authors: Kennedy (Wiradjuri) Michelle , Ninomiya Melody Morton , Ninomiya Maya Morton , Brascoupé (Anishinabeg/Haudenausanee) Simon , Smylie (Mѐtis) Janet , Calma (Kungarakan, Iwaidja) Tom , Mohamed (Narrunga Kaurna) Janine , Stewart (Taungurung) Paul J , Maddox (Bagumani, Modewa) Raglan
Published: July 2024

Objectives

To better understand what knowledge translation activities are effective and meaningful to Indigenous communities and what is required to advance knowledge translation in health research with, for, and by Indigenous communities.

Study design

Workshop and collaborative yarning.

Setting

Lowitja Institute International Indigenous Health Conference, Cairns, June 2023.

Participants

About 70 conference delegates, predominantly Indigenous people involved in research and Indigenous health researchers who shared their knowledge, experiences, and recommendations for knowledge translation through yarning and knowledge sharing.

Results

Four key themes were developed using thematic analysis: knowledge translation is fundamental to research and upholding community rights; knowledge translation approaches must be relevant to local community needs and ways of mobilising knowledge; researchers and research institutions must be accountable for ensuring knowledge translation is embedded, respected and implemented in ways that address community priorities; and knowledge translation must be planned and evaluated in ways that reflect Indigenous community measures of success.

Conclusion

Knowledge translation is fundamental to making research matter, and critical to ethical research. It must be embedded in all stages of research practice. Effective knowledge translation approaches are Indigenous‐led and move beyond Euro‐Western academic metrics. Institutions, funding bodies, and academics should embed structures required to uphold Indigenous knowledge translation. We join calls for reimaging health and medical research to embed Indigenous knowledge translation as a prerequisite for generative knowledge production that makes research matter.
Seroprevalence of Dengue and Hepatitis B infections among young adults attending a secondary health care facility at Olabisi Onabanjo University, Ogun State, Nigeria
Authors: Adekola Hafeez , Agu Georgia , Odeyemi Festus , Egberongbe Haneefat , Onajobi Ismail , Kareem Wahab , Adejonwo Oyesanya
Published: July 2024

Hepatitis B and Dengue virus infections carry significant public health implications due to their potential to cause illness and death. This study focused on examining the prevalence of these infections among young adults seeking care at a secondary health facility at Olabisi Onabanjo University. Ninety samples obtained from study participants underwent screening using Enzyme-linked Immunosorbent Assay (ELISA) for both HBsAg and Dengue IgM. The participants, predominantly female, were aged between 15 and 30 years. The analysis revealed a 13.3% prevalence of Dengue IgM, a 4.5% prevalence of HBsAg, and a 4.4% prevalence for both infections. Regarding age distribution, the highest prevalence occurred among participants aged 15-20 years for both single infections and the co-occurrence of Hepatitis B and Dengue viral infections. Examining gender distribution, female participants exhibited higher seropositivity across all infection categories. Although not statistically significant, these findings lay the groundwork for a comprehensive surveillance study on the Hepatitis B and Dengue viral infections in young adults. This study provides valuable insights into the prevalence patterns of Hepatitis B and Dengue virus, offering a basis for further research and public health interventions in this population.
Evaluation of health care utilisation and mortality in medical hospitalisations with multimorbidity and kidney disease, according to frailty: a nationwide cohort study
Authors: Gregoriano Claudia , Hauser Stephanie , Schuetz Philipp , Mueller Beat , Segerer Stephan , Kutz Alexander
Published: July 2024

INTRODUCTION: The impact of impaired kidney function on healthcare use among medical hospitalisations with multimorbidity and frailty is incompletely understood. In this study, we assessed the prevalence of acute kidney injury (AKI) and chronic kidney disease (CKD) among multimorbid medical hospitalisations in Switzerland and explored the associations of kidney disease with in-hospital outcomes across different frailty strata.
METHODS: This observational study analysed nationwide hospitalisation records from 1 January 2012 to 31 December 2020. We included adults (age ≥18 years) with underlying multimorbidity hospitalised in a medical ward. The study population consisted of hospitalisations with AKI, CKD or no kidney disease (reference group), and was stratified by three frailty levels (non-frail, pre-frail, frail). Main outcomes were in-hospital mortality, intensive care unit (ICU) treatment, length of stay (LOS) and all-cause 30-day readmission. We estimated multivariable adjusted odds ratios (OR) and changes in percentage of log-transformed continuous outcomes with 95% confidence intervals (CI).
RESULTS: Among 2,651,501 medical hospitalisations with multimorbidity, 198,870 had a diagnosis of AKI (7.5%), 452,990 a diagnosis of CKD (17.1%) and 1,999,641 (75.4%) no kidney disease. For the reference group, the risk of in-hospital mortality was 4.4%, for the AKI group 14.4% (adjusted odds ratio [aOR] 2.56 [95% CI 2.52–2.61]) and for the CKD group 5.9% (aOR 0.98 [95% CI 0.96–0.99]), while prevalence of ICU treatment was, respectively, 10.5%, 21.8% (aOR 2.39 [95% CI 2.36–2.43]) and 9.3% (aOR 1.01 [95% CI 1.00–1.02]). Median LOS was 5 days (interquartile range [IQR] 2.0–9.0) in hospitalisations without kidney disease, 9 days (IQR 5.0–15.0) (adjusted change [%] 67.13% [95% CI 66.18–68.08%]) in those with AKI and 7 days (IQR 4.0–12.0) (adjusted change [%] 18.94% [95% CI 18.52–19.36%]) in those with CKD. The prevalence of 30-day readmission was, respectively, 13.3%, 13.7% (aOR 1.21 [95% CI 1.19–1.23]) and 14.8% (aOR 1.26 [95% CI 1.25–1.28]). In general, the frequency of adverse outcomes increased with the severity of frailty.
CONCLUSION: In medical hospitalisations with multimorbidity, the presence of AKI or CKD was associated with substantial additional hospitalisations and healthcare utilisation across all frailty strata. This information is of major importance for cost estimates and should stimulate discussion on reimbursement.
Data quantitative and qualitative study in Brazilian Open Data Portals
Authors: Do Carmo Shirlei L. O. , Geyer Claudio F. R. , Dos Anjos Julio C. S.
Published: July 2024

Open data is a concept attributed to sharing data with anyone, and in addition to being accessed, this data can be manipulated and redistributed. The optimized and interchangeable use of open data can lead to so-called open innovation, which can be understood as the crossing of information between different organizations, to generate more complete and innovative systems and solutions. Despite the clear benefit for society, there are major challenges highlighted in different studies for its implementation, such as the lack of promotion of open data, the lack of standardization in data availability, as well as the lack of complete and updated information, among others. This study uses an available reproducible methodology, to show, through different dimensions, the open data panorama in Brazil, which indicates that there are many opportunities for improvement, in categories such as standardization of data exposure and its licenses, update rate, and, due to the absence of some data, the lack of promotion of open data.
Charge/discharge Profiling of Organic Latent Heat Material Embedded in Polymer Matrix for Heat Energy System
Authors: RAHMAN Reza Abdu , SULISTYO Sulistyo , UTOMO M.S.K.Tony Suryo , FEBRIANSYAH Ilham , ISMAIL Ismail
Published: July 2024

The operational aspect of a latent thermal energy storage (LTES) system is highly dependent on the performance of its latent heat storage material (LHSM). In this work, performance evaluation of the LHSM is conducted using low-density polyethylene (LDPE) and linear LDPE. As an initial assessment, three different organic LHSMs are used for the evaluation. The thermal assessment indicates that the heat of fusion for the LHSM varies between 142.45 J/g and 198.8 J/g. Thermal decomposition demonstrates that the LHSM is suitable for operating a thermal power system under 100 °C. The addition of polymer clearly influences the charge/discharge rate for each LHSM. For example, it has a positive influence on paraffin wax, which increases the charge rate up to 54.4 %. A positive outcome is also observed for palmitic acid, which has the highest charge rate at around 4.4 °C/min. Interestingly, the charge/discharge rate for stearic acid is decreased by the presence of a polymer. It implies that the melting/solidification rate can be decreased, which may be advantageous for passive thermal systems. In general, the addition of LDPE/LLDPE alters the performance of LHSM. It makes the polymer suitable to be taken as a stabilizer for the LHSM.