bluuebunny/crossref_metadata_2025 huggingface dataset:
Emerging Trends in Personality Identification Using Online Social Networks—A Literature Survey
Authors: Kaushal Vishal , Patwardhan Manasi
Published: January 2018

Personality is a combination of all the attributes—behavioral, temperamental, emotional, and mental—that characterizes a unique individual. Ability to identify personalities of people has always been of great interest to the researchers due to its importance. It continues to find highly useful applications in many domains. Owing to the increasing popularity of online social networks, researchers have started looking into the possibility of predicting a user's personality from his online social networking profile, which serves as a rich source of textual as well as non-textual content published by users. In the process of creating social networking profiles, users reveal a lot about themselves both in what they share and how they say it. Studies suggest that the online social networking websites are, in fact, a relevant and valid means of communicating personality. In this article, we review these various studies reported in literature toward identification of personality using online social networks. To the best of our knowledge, this is the first reported survey of its kind at the time of submission. We hope that our contribution, especially in summarizing the previous findings and in identifying the directions for future research in this area, would encourage researchers to do more work in this budding area.
Association between CD4 Cell Count and Blood Pressure and Its Variation with Body Mass Index Categories in HIV-Infected Patients
Authors: Dimala Christian Akem , Kadia Benjamin Momo , Kemah Ben-Lawrence , Tindong Maxime , Choukem Simeon-Pierre
Published: January 2018

The aim of this study was to establish whether an independent relationship exists between CD4 count and hypertension and if this relationship is modified or confounded by the body mass index (BMI). Methods. A secondary data analysis of a cross-sectional study on 200 HIV/AIDS patients at a referral hospital in Cameroon was conducted. Linear and logistic regression models were used as appropriate to explore the association between the variables of interest. Results. There was no linear association between log CD4 count and both systolic (p=0.200; r=0.12) and diastolic blood pressures (p=0.123; r=0.14), respectively. After adjusting for BMI, patients with CD4 count ≥ 350 cells/μl were more likely to have hypertension than those with CD4 count < 350 cells/μl (AOR: 2.50, 95% CI: 1.05–5.93, and p=0.032). There was no effect modification from BMI (test of homogeneity, p=0.721). There was no independent relationship between CD4 count and hypertension after controlling for age, sex, family history of hypertension, BMI-defined overweight, HAART use, and duration of HIV infection (AOR: 1.66, 95% CI: 0.48–5.71, and p=0.419). Conclusion. This study did not identify any independent relationship between CD4 count and hypertension. Large prospective studies are recommended to better explore this relationship between hypertension and CD4 count.
In Vitro Antidiabetic Effects and Antioxidant Potential ofCassia nemophilaPods
Authors: Rehman Gauhar , Hamayun Muhammad , Iqbal Amjad , Ul Islam Saif , Arshad Saba , Zaman Khair , Ahmad Ayaz , Shehzad Adeeb , Hussain Anwar , Lee InJung
Published: January 2018

The antidiabetic and antioxidant potential of ethanolic extract ofCassia nemophilapod (EECNP) was evaluated by three in vitro assays, including yeast glucose uptake assay, glucose adsorption assay, and DPPH radical scavenging activity. The result revealed that the extracts have enhanced the uptake of glucose through the plasma membrane of yeast cells. A linear increase in glucose uptake by yeast cells was noticed with gradual increase in the concentration of the test samples. Moreover, the adsorption capacity of the EECNP was directly proportional to the molar concentration of glucose. Also, the DPPH radical scavenging capacity of the extract was increased to a maximum value of 43.3% at 80 μg/ml, which was then decreased to 41.9% at 100 μg/ml. From the results, it was concluded that EECNP possess good antidiabetic and antioxidant properties as shown by in vitro assays.
Falsely Elevated CA 15-3 Levels in Ovarian Sarcoidosis with Peritoneal Involvement and Ascites
Authors: Tsiodras Sotirios , Gouloumi Alina-Roxani , Tsakiraki Zoi , Chrelias George , Chrelias Charalambos , Loukides Stylianos , Panayiotides Ioannis
Published: January 2018

A rare case of ovarian sarcoidosis with peritoneal and omental involvement presenting as an ovarian malignancy is presented. Clinical, laboratory, and radiological evaluation of the patient revealed ascites and high levels of serum CA 125 and CA 15.3. The diagnosis of sarcoidosis was confirmed with pathology findings on tissues obtained during surgical laparotomy. Establishing the diagnosis of sarcoidosis can be treacherous and was complicated in this case by the falsely elevated biomarkers and ascites.
Variations in Bioactive Content in Different Tomato Trusses due to Elicitor Effects
Authors: Ávila-Juárez Luciano , Miranda-Rodríguez Herminio
Published: January 2018

The tomato fruit is rich in bioactive compounds with antioxidant activity, the levels of which can vary over time in response to biotic and abiotic factors, including the application of elicitors. We investigated the effects of foliar spray of methyl jasmonate (MeJ), salicylic acid (SA), nitric oxide (NO), and hydrogen peroxide (H2O2) on tomato plants every 15 days until the end of cultivation. We measured the levels of bioactive compounds, antioxidant activity, and physiological parameters in three distinct trusses. With the exception of plant length, the elicitors had no effects on physiological parameters, whereas they did have an effect on lycopene content, bioactive compound levels, and antioxidant activity in the three sampled trusses. A strong correlation between bioactive compounds and antioxidant activity was found for the elicitors, particularly MeJ. Our results indicate that certain bioactive compounds and their antioxidant activities vary not only between trusses but also based on the specific elicitor used.
Prevalence of and Factors Associated with Emergency Contraceptive Use among Female Undergraduates in Arba Minch University, Southern Ethiopia, 2015: A Cross-Sectional Study
Authors: Habitu Yohannes Ayanaw , Yeshita Hedija Yenus , Dadi Abel Fekadu , Galcha Desta
Published: January 2018

Emergency contraceptives (ECs) need to be available and used appropriately as a backup in case regular contraception is not taken by people like university students. This study was conducted to assess emergency contraception use and its associated factors among female undergraduates of Arba Minch University. A cross-sectional study was conducted among 515 undergraduates using a structured questionnaire. Respondents were selected by the stratified random sampling technique and data were analyzed using SPSS version 20. Bivariate and multivariate logistic regression models were fitted to identify associated factors. The adjusted odds ratio with a 95% confidence interval was used to present the identified risk factors. The prevalence of emergency contraception use among Arba Minch University students was 78.0% (95% CI: 71.5%, 84.5%). Better information about emergency contraceptives (AOR = 6.3; 95% CI: 2.4, 9.7), good approach of EC service providers (AOR = 9.3; 95% CI: 2.4, 11.6), and positive attitude about ECs (AOR = 2.4; 95% CI: 1.5, 7.2) were factors significantly associated with EC use. The prevalence of emergency contraceptive use noted in this study was comparatively higher than the results found by previous studies conducted in Africa and Ethiopian universities. Continuing support for and wider dissemination of the class are recommended. The fact that the students/participants readily accepted the preceding provisions made such positive findings possible and sustainable.
Calcitriol Prevents Cardiovascular Repercussions in Puromycin Aminonucleoside-Induced Nephrotic Syndrome
Authors: Cátia Fernandes-Cerqueira , Janete Quelhas-Santos , Benedita Sampaio-Maia , Liliana Simões-Silva , Isabel Soares-Silva , Roberto Roncon-Albuquerque , Manuel Pestana
Published: January 2018

Puromycin aminonucleoside-induced nephrotic syndrome (PAN-NS) is characterized by cardiac remodeling and increased local inflammatory activity. Patients with NS and animal models of NS have vitamin D3 deficiency. The aim of the present study was to evaluate the influence of calcitriol on cardiac remodeling and local inflammatory state in PAN-NS rat model. Male Sprague-Dawley rats were injected with PAN or vehicle on day 0. PAN and control rats were divided into two subgroups for the administration of calcitriol (PAN-D and Ct-D groups) or the vehicle (PAN-V and Ct-V groups) during 21 days. On day 21, the renal function, metabolic balance, calcitriol and FGF-23 plasma levels, prohypertrophy and proinflammatory markers (ET-1, TGF-β1, TNF-α, and IL-1β), and calcium signaling molecules (PLB and SERCA-2a) were evaluated. Twenty-one days after injection, PAN-V group presented cardiac hypertrophy and a modulation of proinflammatory markers local expression. Calcitriol treatment of PAN rats prevented cardiac hypertrophy and was associated with marked reduction in the cardiac expression levels of proinflammatory markers. Our results suggest that vitamin D3 deficiency in PAN-NS may contribute to cardiac remodeling and to the increase in local inflammatory activity. Calcitriol treatment prevents both cardiac repercussions and local inflammatory processes in PAN-NS.
Hippocampal Pathophysiology: Commonality Shared by Temporal Lobe Epilepsy and Psychiatric Disorders
Authors: Nakahara Soichiro , Adachi Megumi , Ito Hiroyuki , Matsumoto Mitsuyuki , Tajinda Katsunori , Erp Theo G. M. van
Published: January 2018

Accumulating evidence points to the association of epilepsy, particularly, temporal lobe epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses, the hippocampus is considered the regional focal point of the brain, playing an important role in cognition, psychosis, and seizure activity and potentially suggesting common etiologies and pathophysiology of TLE and schizophrenia. In the present review, we overview abnormal network connectivity between the dentate gyrus (DG) and the Cornus Ammonis area 3 (CA3) subregions of the hippocampus relative to the induction of epilepsy and schizophrenia. In light of our recent finding on the misguidance of hippocampal mossy fiber projection in the rodent model of schizophrenia, we discuss whether ectopic mossy fiber projection is a commonality in order to evoke TLE as well as symptoms related to schizophrenia.
Influence of Manufacturing Methods of Implant-Supported Crowns on External and Internal Marginal Fit: A Micro-CT Analysis
Authors: Moris Izabela C. M. , Monteiro Silas Borges , Martins Raíssa , Ribeiro Ricardo Faria , Gomes Erica A.
Published: January 2018

Aim.To evaluate the influence of different manufacturing methods of single implant-supported metallic crowns on the internal and external marginal fit through computed microtomography.Methods.Forty external hexagon implants were divided into 4 groups(n=8), according to the manufacturing method: GC, conventional casting; GI, induction casting; GP, plasma casting; and GCAD, CAD/CAM machining. The crowns were attached to the implants with insertion torque of 30 N·cm. The external (vertical and horizontal) marginal fit and internal fit were assessed through computed microtomography. Internal and external marginal fit data (μm) were submitted to a one-way ANOVA and Tukey’s test(α=.05). Qualitative evaluation of the images was conducted by using micro-CT.Results.The statistical analysis revealed no significant difference between the groups for vertical misfit(P=0.721). There was no significant difference(P>0.05)for the internal and horizontal marginal misfit in the groups GC, GI, and GP, but it was found for the group GCAD(P≤0.05). Qualitative analysis revealed that most of the samples of cast groups exhibited crowns underextension while the group GCAD showed overextension.Conclusions.The manufacturing method of the crowns influenced the accuracy of marginal fit between the prosthesis and implant. The best results were found for the crowns fabricated through CAD/CAM machining.
A Case of Primary Uterina Lymphoma Presenting with Bleeding, Pelvic Pain, and Dysmenorrhea
Authors: Miura Lilian Yukari , Maure Miriam Anyury Daquin , Zomer Monica Tessmann , Ribeiro Reitan , Cavalcanti Teresa Cristina Santos , Kondo William
Published: January 2018

Primary non-Hodgkin’s lymphoma (NHL) can arise from lymphatic cells located in solid organs (extranodal) and it accounts for 25 to 35% of all NHL. Primary lymphoma on the female genital tract (PLFGT) is a rare disease, comprising 0.2 to 1.1% of all extranodal lymphomas in the female population. In this paper, the authors report an extremely rare case of a 48-year-old woman who exhibited an abnormal uterine bleeding, pelvic pain, and dysmenorrhea history. The transvaginal ultrasound showed an anteverted uterus measuring 153 cm3 in volume, with intramural leiomyomas. She underwent a total laparoscopic hysterectomy with bilateral salpingectomy. The histologic evaluation of the specimen showed a follicular lymphoma with diffuse pattern in the endometrium. This report illustrates the difficulty in the diagnosis of primary lymphomas of the female genital tract.
A Rare Cause of a Fluctuating Cystic Lesion in the External Auditory Canal
Authors: Esmaili Aaron , Wang Allen Y. Y. , Kuthubutheen Jafri
Published: January 2018

Temporomandibular joint (TMJ) ganglionic cyst is an uncommon entity and only a few have been reported in the literature. TMJ ganglion within the external auditory canal presenting clinically as a fluctuating cystic lesion has never been reported. Here, we present a unique case of such a lesion together with otoscopic and radiological images as well as provide a descriptive review of TMJ ganglionic cysts.
Fluoride Variations in Rivers on the Slopes of Mount Meru in Tanzania
Authors: Kitalika Aldo J. , Machunda Revocatus L. , Komakech Hans C. , Njau Karoli N.
Published: January 2018

This study reports the variations of fluoride ions in rivers on the slopes of Mount Meru in the northern part of Tanzania. More than 318 water samples were collected from Temi, Nduruma, Tengeru, and Maji ya Chai Rivers in both wet (mid-March and April) and dry (August) seasons. The samples were analyzed for fluoride levels using Ion Selective Electrode (ISE). The minimum and maximum average fluoride levels in the wet season were 0.24±0.03 mg/l and 65.20±0.03 mg/l, respectively, whereas the average lowest and highest levels in the dry season were 1.02±0.02 mg/l and 69.01±0.03 mg/l, respectively. Tengeru River had the lowest fluoride levels in both seasons, whereas Maji ya Chai recorded the highest fluoride levels in both seasons. The headwater of all rivers with the exception of Maji ya Chai met the World Health Organization’s (WHO) maximum acceptable fluoride levels of 1.50 mg/l and the downstream environment qualified for Tanzania Bureau of Standards (TBS) maximum permissible fluoride concentration in drinking water of 4.00 mg/l. Also, the laboratory experiments showed that fluoride containing rocks exposed to pH above 7.6 display high leaching of F− in solution which gradually increased with the increase in pH, indicating that dissolution of fluoride in water is a function of pH.
Identification of a Novel Mutation in a Family with Pseudohypoparathyroidism Type 1a
Authors: Moutinho Adelaide , Carvalho Rosa , Ferreira Reis Rita , Tavares Sandra
Published: January 2018

Introduction. Pseudohypoparathyroidism type 1a is caused by GNAS mutations leading to target organ resistance to multiple hormones rather than parathyroid hormone, resulting not only in hypocalcemia, but also in Albright’s hereditary osteodystrophy phenotype. Materials and Methods. DNA sequencing of the GNAS gene identified a novel heterozygous mutation in peripheral blood leukocytes in the family presented in this case report. Results. We present a case of a 25-year-old woman with pseudohypoparathyroidism type 1a admitted with seizures, whose family presents an autosomal dominant transmission of a novel heterozygous GNAS mutation (c.524_530+3del). Conclusion. Pseudohypoparathyroidism type 1a is mostly caused by inactivating GNAS mutations that have been gradually reported in the literature that lead to a typical and complex clinical phenotype and resistance to multiple hormones. The deletion caused by the mutation identified in the presented case has not been reported previously.
Ischemic Preconditioning Promotes Autophagy and Alleviates Renal Ischemia/Reperfusion Injury
Authors: Xie Ying , Xiao Jing , Fu Chensheng , Zhang Zhenxing , Ye Zhibin , Zhang Xiaoli
Published: January 2018

Autophagy is important for cellular survival during renal ischemia/reperfusion (I/R) injury. Ischemic preconditioning (IPC) has a strong renoprotective effect during renal I/R. Our study here aimed to explore the effect of IPC on autophagy during renal I/R injury. Rats were subjected to unilateral renal ischemia with or without prior IPC. Hypoxia/reoxygenation (H/R) injury was induced in HK-2 cells with or without prior hypoxic preconditioning (HPC). Autophagy and apoptosis were detected after reperfusion or reoxygenation for different time. The results showed that the levels of LC3II, Beclin-1, SQSTM1/p62, and cleaved caspase-3 were altered in a time-dependent manner during renal I/R. IPC further induced autophagy as indicated by increased levels of LC3II and Beclin-1, decreased level of SQSTM1/p62, and accumulation of autophagosomes compared to I/R groups at corresponding reperfusion time. In addition, IPC reduced the expression of cleaved caspase-3 and alleviated renal cell injury, as evaluated by the levels of serum creatinine (Scr), neutrophil gelatinase-associated lipocalin (NGAL), and kidney injury molecule-1 (KIM-1) in renal tissues. In conclusion, autophagy and apoptosis are dynamically altered during renal I/R. IPC protects against renal I/R injury and upregulates autophagic flux, thus increasing the possibility for a novel therapy to alleviate I/R-induced acute kidney injury (AKI).
UGT1A1Genetic Variations and a Haplotype Associated with Neonatal Hyperbilirubinemia in Indonesian Population
Authors: Wisnumurti Dewi A. , Sribudiani Yunia , Porsch Robert M. , Maskoen Ani M. , Abdulhamied Lola I. , Rahayuningsih Sri E. , Asni Eni K. , Sleutels Frank , Kockx Christel E. M. , van Ijcken Wilfred F. J. , Sukadi Abdurachman , Achmad Tri H.
Published: January 2018

Neonatal hyperbilirubinemia (NH) is a common finding in newborn babies in Indonesia. Common and rare variants ofUGT1A1have been known to contribute to NH etiology. This study aims to identifyUGT1A1genetic variation and haplotype associated with NH in Indonesian population. DNA was isolated from 116 cases and 115 controls and a targeted-deep sequencing approach was performed on the promoter, UTRs, and exonic regions ofUGT1A1. Determining association of common variants and haplotype analysis were performed using PLINK and Haploview. Ten and 4 rare variants were identified in cases and controls, respectively. TheUGT1A1rare variants frequency in cases (5.17%) was higher than that in controls (1.7%). Four of those rare variants in cases (p.Ala61Thr, p.His300Arg, p.Lys407Asn, and p.Tyr514Asn) and three in controls (p.Tyr79X, p.Ala346Val, and p.Thr412Ser) are novel variants. The frequencies of p.Gly71Arg, p.Pro229Gln, and TA7common variants were not significantly different between cases and controls. A haplotype, consisting of 3 major alleles of 3′ UTRs common variants (rs8330C>G, rs10929303C>T, and rs1042640C>G), was associated with NH incidence (p=0.025) in this population. Using targeted-deep sequencing and haplotype analysis, we identified novelUGT1A1rare variants and disease-associated haplotype in NH in Indonesian population.
Breviário de espectrologia e necromancia: uma hipótese referente ao estudo da ficção historiográfica brasileira
Authors: Almeida Marcos Vinícius Lima de
Published: January 2018

Esse breve ensaio vislumbra a relação da escrita com a morte, na historiografia, mas também na ficção histórica, a partir da questão do espectro enquanto sintoma da barbárie, que assombra o presente. A escrita da história, na esteira de Michel de Certau e Jeanne Marie Gagnebin, seria uma espécie de rito sepultamento, uma espécie de necromancia, portanto, um diálogo com os fantasmas do passado.
Static metrics of impact for a dynamic problem: The need for smarter tools to guide suicide prevention planning and investment
Authors: Page Andrew , Atkinson Jo-An , Heffernan Mark , McDonnell Geoff , Prodan Ante , Osgood Nathaniel , Hickie Ian
Published: January 2018

Objectives:

This study investigates two approaches to estimate the potential impact of a population-level intervention on Australian suicide, to highlight the importance of selecting appropriate analytic approaches for informing evidence-based strategies for suicide prevention.

Methods:

The potential impact of a psychosocial therapy intervention on the incidence of suicide in Australia over the next 10 years was used as a case study to compare the potential impact on suicides averted using: (1) a traditional epidemiological measure of population attributable risk and (2) a dynamic measure of population impact based on a systems science model of suicide that incorporates changes over time.

Results:

Based on the population preventive fraction, findings suggest that the psychosocial therapy intervention if implemented among all eligible individuals in the Australian population would prevent 5.4% of suicides (or 1936 suicides) over the next 10 years. In comparison, estimates from the dynamic simulation model which accounts for changes in the effect size of the intervention over time, the time taken for the intervention to have an impact in the population, and likely barriers to the uptake and availability of services suggest that the intervention would avert a lower proportion of suicides (between 0.4% and 0.5%) over the same follow-up period.

Conclusion:

Traditional epidemiological measures used to estimate population health burden have several limitations that are often understated and can lead to unrealistic expectations of the potential impact of evidence-based interventions in real-world settings. This study highlights these limitations and proposes an alternative analytic approach to guide policy and practice decisions to achieve reductions in Australian suicide.
A genealogy of mediation in international relations: From ‘analogue’ to ‘digital’ forms of global justice or managed war?
Authors: Richmond Oliver P
Published: January 2018

What does it mean to mediate in the contemporary world? During the Cold War, and since, various forms of international intervention have maintained a fragile strategic and territorially sovereign balance between states and their elite leaders, as in Cyprus or the Middle East, or built new states and inculcated new norms. In the post-Cold War era intervention and mediation shifted beyond the balance of power and towards the liberal peace, as in Bosnia-Herzegovina, Kosovo, and Timor Leste. In the case of Northern Ireland, identity, territorial sovereignty, and the nature of governance also began to be mediated, leading to hints of complex, post-liberal formulations. This article offers and evaluates a genealogy of the evolution of international mediation.
Understanding the impact of geographies and space on the possibilities of peace activism
Authors: Vogel Birte
Published: January 2018

Current peace research has provided scholars with a range of conceptualizations of what peace is. Further, there is a substantial body of literature on the processes used to build peace – the how of peacebuilding. However, there is little research that examines the question of where peace and peacebuilding occur and how these spaces shape the possibilities of non-state actors to achieve their objectives. This article makes a theoretical and empirical contribution to the emerging debate by sketching out the concept of peace spaces and applying it to the United Nations’ controlled Buffer Zone in Cyprus, the geographical home of inter-communal peacebuilding. To determine how geographies impact on the possibilities of non-state peacebuilding actors, the article focuses on three elements, specifically, on how the physical space impacts on: (a) inclusion/exclusion of participants; (b) protection/control through elite actors; and (c) its influence on the discourses and solutions that can be imagined. The article finds that local and international actors alike make a clear connection between the physical space and political viewpoints, which has both enabling and restricting implications.
The impact of health literacy on diabetes self-management education
Authors: Vandenbosch Jessica , Van den Broucke Stephan , Schinckus Louise , Schwarz Peter , Doyle Gerardine , Pelikan Jürgen , Muller Ingrid , Levin-Zamir Diane , Schillinger Dean , Chang Peter , Terkildsen-Maindal Helle
Published: January 2018

Background:

Diabetes self-management education (DSME) is generally considered to be a key determinant of the treatment outcomes and related costs of diabetes mellitus. While DSME programmes generally have positive outcomes, their effects may depend on certain factors, such as the type of programmes provided and patients’ level of health literacy (HL). Low HL has been associated with poorer self-management behaviours and poor medication adherence in diabetic patients, but its impact on the effects of DSME has not yet been systematically investigated. This study aimed to investigate the influence of HL on the self-reported effects of DSME programmes while taking the type of programme into consideration.

Method:

A total of 366 diabetic patients from nine countries completed a questionnaire measuring HL, self-management behaviours, problem perception, coping, perceived general health and well-being, before and after participating in a DSME programme.

Results:

DSME programmes were found to have positive effects on self-reported self-management behaviours and almost all psychological and health outcomes, regardless of HL level. Patients with high HL scored better on several diabetes outcomes than those with low HL, but all patients described benefiting from DSME. Individual and group-based programmes resulted in more positive effects on several diabetes outcomes than self-help groups, but no interaction with HL was found.

Conclusion:

Our findings confirm those of previous studies showing that DSME programmes have positive effects and that low HL is associated with lower diabetes outcomes but do not support the assumption that the effects of DSME programmes are influenced by the patient’s HL. However, due to the limitations of this study, further investigation is necessary to support these findings and improve our understanding about the impact of HL on DSME programmes’ effectiveness.
Low-energy housing retrofit in North England: Overheating risks and possible mitigation strategies
Authors: Ibrahim Azlizawati , Pelsmakers Sofie LJ
Published: January 2018

In the drive to reduce space-heating demand and associated CO2 emissions as well as tackle fuel poverty, dwelling overheating and summer-time occupant thermal discomfort might be the unintended consequences of low-energy building retrofits. This paper presents the findings of a steady-state modelled low-energy retrofit dwelling in northern England and its potential current and future climate overheating risks using UK Climate Projections 2009 (UKCP09) scenarios (2050 and 2080 High Emission Scenarios). Predictive findings highlight that retrofitting to low-energy standards increases overheating risk over time, unless passive prevention measures are included in the retrofit design. In addition, the steady-state nature of the model might not fully capture the occupants’ exposure to actual future overheating risks. Among the most effective individual passive overheating mitigation strategies are temporary internal shading, permanent external shading and night-time ventilation. Most effective is a combination of these adaptation measures, so that predictive overheating is minimised in a future changing climate, reducing the uptake of active cooling in retrofitted dwellings.

Practical application: Much research focuses on building overheating risks in the warmer South-east of England. However, this paper highlights how dwelling retrofit in north England (Sheffield) also can lead to increased dwelling overheating risk, unless passive design measures are included in the retrofit design. Among the most effective individual passive overheating mitigation strategies are solar shading devices and increased night-time ventilation, though ideally different measures are combined. Using future climate scenarios highlights that retrofits designed today might not be able to provide occupant thermal comfort in a future warming world.
Perceiving Relationship Success Through a Motivational Lens: A Regulatory Focus Perspective
Authors: Cortes Kassandra , Scholer Abigail A. , Kohler Amanda , Cavallo Justin V.
Published: January 2018

The current research examined the hypothesis that the relative importance of growth- and security-related relationship qualities in establishing successful relationships depends on the motivational orientation—regulatory focus (Higgins, 1997)—of the individual. Across four studies, we found that individuals in a promotion focus, whether chronic (Studies 1-2, 4) or temporarily induced (Study 2), prioritized the presence of relationship growth versus security in perceiving relationship success (Studies 1-2), rated their own relationship well-being higher when growth (but not security) qualities were present (Study 3), and experienced heightened relationship well-being when room for growth was manipulated to appear abundant versus limited (Study 4). In contrast, prevention-focused individuals did not place as much emphasis on growth relative to security (Studies 1 and 3) and, when forced to choose, preferred a relationship characterized by security versus growth (Study 2). These findings suggest the value of considering motivational orientations in understanding how relationship success is experienced.
Cultural Self-Awareness as Awareness of Culture’s Influence on the Self: Implications for Cultural Identification and Well-Being
Authors: Lu Chieh , Wan Ching
Published: January 2018

Cultural self-awareness refers to the awareness of how culture has influenced the self. This research investigated how such awareness might be related to cultural identification and well-being. In Study 1, we developed a scale measure that differentiated individuals’ awareness of how culture has influenced them (cultural self-awareness) and how their own personality and personal experiences have influenced them (personal self-awareness). Factor analysis and item analysis showed a two-factor model with acceptable scale reliability. Study 2 showed that cultural self-awareness positively predicted well-being through higher cultural identification, whereas personal self-awareness positively predicted well-being through higher behavioral authenticity. Study 3 manipulated the valence of individuals’ cultural experience. The indirect effect of cultural self-awareness on well-being was stronger when cultural experience was positive (vs. negative). Study 4 provided a specific cultural context for the well-being measures and replicated the findings of Studies 2 and 3. Implications on the link between culture and self were discussed.
Knowledge, Emotion, and Power in Social Partnership: A turn to partners’ context
Authors: Nguyen ToTran , Janssens Maddy
Published: January 2018

Departing from the social partnership field’s structural, static view of context, this study takes on a situated, emergent view to explore how the partnership process unfolds. Applying ethnomethodologically informed conversation analysis to partners’ meeting talk, we discover that three interactional orders – epistemic, emotional and deontic rights and obligations – are crucial resources for how partners construct and transform their context. We advance the field by first demonstrating how knowledge, emotion, and power – corresponding to the three orders – are not contextual elements that determine the partnership process but are rather ongoing accomplishments that play a ‘doubly contextual’ role in how the process unfolds; they shape context and are also shaped by it. Second, we expose the precarious interfaces of knowledge, emotion and power and show that at such interfaces, interactional trouble unfolds processually through partners disattending, superimposing and equivocating certain rights and obligations. We conclude with reflections on what this study means for reimagining social partnerships.
In-stent restenosis: surgical and histopathological perspective
Authors: Srimurugan Balaji , Sigler Matthias , Sankar Nainar Madhu , Cherian Kotturathu Mammen
Published: January 2018

Background

In-stent restenosis has been recognized as a distinct clinical entity that warrants a repeat procedure either in the form of percutaneous reintervention or coronary artery bypass grafting. Multivessel grafting with endarterectomy and explantation of the stent is rarely performed, with few cases reported in the literature. We aim to study the pathomorphology of the stent-vascular interface in coronary vessels undergoing in-stent restenosis.

Methods

Over a period of 3 years, 3 patients who had undergone angioplasty for diffuse coronary artery disease developed in-stent restenosis and were advised coronary artery bypass. The mean age was 53 years, the average time from the previous intervention was 77 months. Coronary endarterectomy with stent removal and concomitant multivessel coronary artery bypass was performed.

Results

Histology showed significant proliferation of the well-endothelialized intima as the reason for in-stent restenosis. There were no signs of local thrombus formation or increased inflammatory activity in any of the specimens. After coronary artery bypass, all patients were asymptomatic at a mean follow-up of 32 months.

Conclusion

Coronary endarterectomy with stent explantation and multivessel coronary artery bypass is a procedure that requires attention because the need is increasing due to the rise in the number of angioplasties. The complexity of this procedure increases to the extent that the adventitia is involved during stent explantation.
An Analysis of Growth and Association between Labour Productivity and Wages in Indian Textile Industry
Authors: Ahlawat Vanita , Renu
Published: January 2018

India is one of the largest textile producers in the world. Textile industry is huge employment-providing industry after agriculture in India. The present article is an attempt to analyse first, the growth and composition of employees engaged in textile industry in India. Second, to find the growth and relation between employments, man-days employed, wages and net value added (NVA) by textile industry in India. And lastly, the impact of labour productivity in wage determination is also analysed. The results suggested that there is huge gender disparity in employment, that is, women are very few in comparison to men workers. Overall employment in textile has an increasing trend among both categories of textile industry. Further, spinning, weaving and finishing of textile manufacturing is growing faster than manufacturing of other textiles. Employment in textile industry has a positive and significant correlation with real wage rates in both categories of industries. This indicates that increase in real wage rate causes enhancement in employment in textile manufacturing. And further results suggest that labour productivity is a significant determinant of wage rate of textile employees.
Policing unacceptable protest in England and Wales: A case study of the policing of anti-fracking protests
Authors: Jackson Will , Gilmore Joanna , Monk Helen
Published: January 2018

In recent years public order policing policy in England and Wales has undergone significant changes. A ‘human rights compliant’ model of protest policing has been developed since 2009 and this article makes a contribution to the body of academic work considering the impact of these changes on operational policing. Drawing upon a longitudinal case study of the policing of protests against ‘fracking’ in Salford, Greater Manchester, in 2013–14, the article contrasts post-2009 policy and academic discourses on protest policing with the experiences of anti-fracking protesters. To develop this assessment, the article also draws attention to previously unexplored definitions of acceptable and unacceptable protest set out by police in more recent policy, and considers the extent to which these definitions are reflected in the police response to anti-fracking protest. The article suggests that a police commitment to a human rights approach to protest facilitation is, at least in the case of anti-fracking protest, contingent on the focus and form of political activism.
Secularism in Bangladesh
Authors: Islam Md Maidul
Published: January 2018

Ever since Bangladesh became independent in 1971 and proclaimed secularism among its four-pronged constitutional core objectives, the world’s third largest Muslim country has been struggling with this concept and its practical manifestations. The temptation of misusing religion in heavily politicised contexts and contestations over social, political and economic interests and development remains ever-present. The violently antagonistic relations between secular and non-secular forces, this article offers some fresh insights into the dynamics of relationships between religion, politics and Islamist militancy in contemporary Bangladesh through discourse analysis. While the hegemonic nature of the deeply contested state apparatus has dominated the headlines, the space for secularism as a sustainable common platform for all people of Bangladesh has appeared to be shrinking. However, this article shows that not all is lost, provided new balances can be found.
Climate Change Policy of India
Authors: Saryal Rajnish
Published: January 2018

Since the 1970s, and especially following the 1992 Rio Earth Summit, climate change has become an area of high politics, engaging the whole world at the international and diplomatic level. What matters, though, is how this translates into tangible policies at national and local levels, and how these different scales interact. Highlighting India’s unique position in international climate negotiations, this article first scrutinises various official statements and documents of the Government of India (GOI) on climate change and puts them into an analytical framework that demonstrates continuities, but also significant recent shifts. Investigating the reasons for such modifying trends and examining their consequences, the article then suggests that partly owing to recent changes in global and (geo)political contexts, but also due to an Indian re-thinking of responsibility for addressing global climate change, there is a significant new development. This seems to augur a South Asian ‘silent revolution’ in green technologies, a prudent, economically and ecologically beneficial step, not only for India but possibly a sustainable global model.
The information-seeking behavior of aquaculture researchers at the Southeast Asian Fisheries Development Center
Authors: Superio Daryl L , Canaman Jessica B , Jaco Janet P , Estember Melda L
Published: January 2018

Understanding the information-seeking behavior of library patrons is essential for the library to provide quality resources and services, and to satisfy its patrons’ information needs. A quantitative research was conducted to describe the information searching and using behaviors of the Filipino aquaculture scientists, researchers and research staff at the Aquaculture Department of the Southeast Asian Fisheries Development Center (SEAFDEC/AQD). The study revealed that although the respondents find it useful to go to the library to get assistance from the librarian, and to browse and read current acquisitions related to their research, they visited the library infrequently. However, remote library services, especially email and phone services, were highly utilized. When searching for information, the Internet, mainly via search engines, was highly preferred rather than visiting the Library and using its online public access catalog (OPAC) or its databases. The combination of print and electronic formats was highly preferred when reading, rather than print only or electronic-only. The majority would print and save the retrieved electronic copy.
What has America been singing about? Trends in themes in the U.S. top-40 songs: 1960–2010
Authors: Christenson Peter G. , de Haan-Rietdijk Silvia , Roberts Donald F. , ter Bogt Tom F.M.
Published: January 2018

This study explored 19 themes embedded in the lyrics of 1,040 U.S. top-40 songs from 1960 through 2010, using R strucchange software to identify trends and breaks in trends. Findings reveal both continuity and change. As in 1960, the predominant topic of pop music remains romantic and sexual relationships. However, whereas the proportion of lyrics referring to relationships in romantic terms remained stable, the proportion including reference to sex-related aspects of relationships increased sharply. References to lifestyle issues such as dancing, alcohol and drugs, and status/wealth increased substantially, particularly in the 2000s. Other themes were far less frequent: Social/political issues, religion/God, race/ethnicity, personal identity, family, friends showed a modest occurrence in top-40 music throughout the studied period and showed no dramatic changes. Violence and death occurred in a small number of songs, and both increased, particularly since the 1990s. References to hate/hostility, suicide, and occult matters were very rare. Results are examined in the context of cultural changes in the social position of adolescents, and more specifically in light of the increased popularity of rap/hip-hop music, which may explain the increases in references to sex, partying, dancing, drug use, and wealth.
Tea polyphenols inhibit the proliferation, migration, and invasion of melanoma cells through the down-regulation of TLR4
Authors: Chen Xianjin , Chang Lili , Qu Yan , Liang Jinning , Jin Waishu , Xia Xiujuan
Published: January 2018

Melanoma is the most common skin cancer and malignant melanoma which can cause skin cancer-related deaths. Toll-like receptor 4 (TLR4) had been reported to play an important role in melanoma, and tea polyphenol (TP) is regarded as an anticancer substance. However, the relationship between TP and TLR4 in melanoma is not well explored. Therefore, our aim is to figure out how TP has an influence on melanoma. Melanoma cell lines (B16F10 and A375) were treated with TP and lipopolysaccharides (LPS). Western blot assay was used to examine TLR4 expression, and MTT assay was conducted to assess proliferation. Wound healing assay was conducted to evaluate the migration of melanoma cells, and transwell assay was used to examine the melanoma cells’ invasiveness. Besides, in vivo experiments were practiced for TP function in mice with melanoma cells. TP inhibited the proliferation, migration and invasion ability of melanoma cells, which displayed a dosage and time dependence. TLR4 was highly expressed in melanoma cells compared with normal skin cells. TP could suppress TLR4 expression both in normal melanomas and in stimulated melanomas by TLR4 agonist LPS. Suppressing TLR4 in melanomas could inhibit cell function (proliferation, migration, and invasion), and blocking the expression of 67LR could abolish TP function on TLR4. TP can inhibit melanoma (B16F10) growth in vivo.
Outcomes and Costs of Patients Admitted to the Intensive Care Unit Due to Accidental or Intentional Poisoning
Authors: Fernando Shannon M. , Reardon Peter M. , Ball Ian M. , van Katwyk Sasha , Thavorn Kednapa , Tanuseputro Peter , Rosenberg Erin , Kyeremanteng Kwadwo
Published: January 2018

Introduction:

Acute poisoning represents a major cause of morbidity and mortality, and many of these patients are admitted to the intensive care unit (ICU). However, little is known regarding ICU costs of acute poisoning.

Methods:

This was a retrospective matched database analysis of patients admitted to the ICU with acute poisoning from 2011 to 2014. It was performed in 2 ICUs within a single tertiary care hospital system. All patient information, outcomes, and costs were stored in the hospital data warehouse. Control patients were defined as randomly selected age-, sex-, severity index-, and comorbidity index-matched nonpoisoned ICU patients (1:4 matching ratio).

Results:

A total of 8452 critically ill patients were admitted during the study period, of whom 277 had a diagnosis of acute poisoning. The mean age was 44.5 years, and the most common xenobiotics implicated were sedative hypnotics (20.2%), antidepressants (15.2%), and opioids (10.5%). Of these, 73.6% of poisonings were deemed intentional. In-hospital mortality of poisoned patients was 5.1%, compared to 11.1% for control patients ( P < .01). The median ICU length of stay (LOS) for poisoned patients was 3.0 days, compared with 4.0 days for control patients ( P < .01). The mean total cost for poisoned patients was CAD$18 958. Control patients had a significantly higher mean total cost of CAD$60 628 ( P < .01). The xenobiotics associated with the highest costs were acetaminophen (CAD$18 585), toxic alcohols (CAD$16 771), and opioids (CAD$12 967).

Conclusions:

In our cohort, we confirmed the long-held belief that patients admitted to the ICU with a primary diagnosis of poisoning have a lower mortality rate, ICU LOS, and overall cost per ICU admission than nonpoisoned patients. However, poisoned patients still accrue significant daily costs, with the highest costs attributed to xenobiotics with known antidotes, such as acetaminophen, toxic alcohols, and opioids.
Normal Baseline Function Is Associated With Delayed Rehabilitation in Critically Ill Children
Authors: Miura Shinya , Wieczorek Beth , Lenker Hallie , Kudchadkar Sapna R.
Published: January 2018

Background:

Early mobilization of patients in the adult intensive care unit (ICU) is associated with improved functional outcomes and shorter ICU stay. Although emerging evidence suggests that early mobilization in pediatric ICUs (PICUs) is safe and feasible, physical therapist (PT) consultation may be delayed because of perceptions that patient acuity precludes mobilization activities. Factors that influence timely involvement of PTs to facilitate acute rehabilitation in critically ill children have not been characterized. The aim of this study was to identify patient-level factors for early PT consultation in a tertiary care PICU before large-scale implementation of a multicomponent early mobilization program.

Methods:

We conducted a retrospective analysis of data from the PICU Up! Quality Improvement Initiative. The primary outcome was early rehabilitation, defined as PT consultation within the first 3 days of PICU admission. Patients (n = 100) were divided into 2 groups by outcome, and predictive factors for early rehabilitation were analyzed with logistic regression.

Results:

Of 100 children, 54% received early rehabilitation. In univariate analyses, higher pediatric risk of mortality (PRISM) score ( P < .001), baseline motor impairment ( P < .01), developmental delay ( P = .04), mechanical ventilation ( P = .1), and number of devices ( P = .01) were associated with early rehabilitation. In a logistic regression model, predictive factors for early rehabilitation included baseline motor impairment (adjusted odds ratio = 5.36, 95% confidence interval [CI] = 1.3-22.0) and higher PRISM score (adjusted odds ratio = 1.17, 95% CI = 1.02-1.34).

Conclusions:

Critically ill children with normal baseline function or lower acuity of illness are less likely to have initiation of early rehabilitation with PT prior to implementation of a unit-wide early mobilization program. Baseline motor impairment and higher PRISM scores were independently associated with early rehabilitation. These findings highlight the need for streamlined criteria for PT consultation to meet the rehabilitation needs of all critically ill patients.