bluuebunny/crossref_metadata_2025 huggingface dataset:
DETERMINATION OF THE MAIN PARAMETERS OF THE UPGRADED HYDROSTATIC BEARING TAKING INTO ACCOUNT SHAFT DISPLACEMENT UNDER LOAD
Authors:   Chernihiv Polytechnic National University, Sakhno Yevgeniy
Published: June 2022

It is known that one of the reasons that requires determining the design and operating parameters of the upgraded hy-drostatic bearing is vibration, which is caused by unbalance of the technological system. In this case, the designer has to reduce the speed of rotation of the spindle, which reduces the efficiency of high-speed machining.One of the promising areas of modernization and efficient operation of hydrostatic bearings is automatic adjustment of stiffness and their load-bearing capacity without changing the geometric parameters of the bearing. Due to the design features of the machine components and its aggregates, bearings must meet the established standards, so the task is to increase the operational parameters of the supports byimproving their structural elements.Analysis of research and publications in the field of modernization of hydrostatic bearings has shown that the issues of controlling shaft movements under loads during rotation of the Rotary unit are currently given little attention in the scientific literature.The aim of this paper is to develop theoretical approaches and practical recommendations for designing a new power supply system for hydrostatic supports to stabilize the position of the shaft when it isdisplaced under load along the entire plane of the hydrostatic bearing.When solving the problem of designing automatic shaft movement control systems in a hydrostatic bearing during vari-able loads, the problem of controlling the oil gap compensation process in the shaft-bearing interface arises, which solution reduces vibrations, power load on a shaft and wear of its support necks.In this paper, we consider the design of a new power supply system for hydrostatic supports and simulate the processes of movement of the working fluid in the upgraded bearing, which are quite relevant, and their solution allows you to control the position of the shaft during machine operation
Почтовые марки периода Тувинской Народной Республики как отражение эволюции общественного сознания тувинцев
Authors: Воронин Роман Михайлович
Published: June 2022

Почтовые марки являются объектами, обладающими уникальными свойствами, отличающими их от других исторических документов. Изображения на марках несут, помимо важной исторической информации, эмоциональный след ушедшей эпохи, запечатленный художниками, которые существовали и творили в конкретном культурно-историческом пространстве. Целью настоящей работы явилось исследование почтовых марок Тувинской Народной Республики с точки зрения отражения эволюции общественного сознания тувинцев. Представлено описание наиболее значимых марок, позволяющих оценить важнейшие этапы развития тувинского общества 1920-х — 1940-х годов.
Первые выпуски марок ТНР подчеркивают теснейшую культурную, религиозную, экономическую связь молодой республики с Монголией: номиналы в мунгу и тугриках, надписи старомонгольским алфавитом, изображение буддийского колеса «хорлоо», которое также присутствует на первом гербе нового государства. По мере формирования национального мышления, становления государственности в сознании тувинцев, происходит эволюция изображения герба на марках: буддийское колесо «хорлоо» (1926 г.) сменяют колосья, красная звезда, серп и молот (1943 г.). Изображение государственной границы ТНР также трансформируется: от условного пунктира по монгольской территории в 1927 г. до четкой жирной линии на марках 1935 г.
Важным фактором стал процесс возникновения национальной письменности и валюты. Марки 1932 г. с надписями на трех языках (старомонгольском, тувинской латинице и английском) иллюстрируют период до введения кириллического письма в 1941 г., естественным образом помещающего Туву в культурное пространство Советского Союза. Уникальная марка 1934 г. с номиналом сразу в двух денежных единицах — в рублях, и в никогда не существовавших тувинских тугриках, предвосхищает мечту о национальной валюте, позднее воплотившуюся в акша.
Очевидно, что марки являются инструментом пропаганды, фактором влияния, внедряющим определенные культурно-смысловые коды в общество. Но этот инструмент не мог эффективно функционировать без опоры на уже сложившиеся общественные отношения. Создатели марок вынуждены были считаться с реальным положением дел в республики, должны были отражать насущные чаяния тувинского народа.
Этноязыковая ситуация как фактор социального самочувствия региона в национальных республиках России (на примере Тувы, Башкортостана и Калмыкии)
Authors: Туракаев Марсель Салаватович
Published: June 2022

В статье определяется степень влияния некоторых показателей этноязыковой ситуации в республиках России на социальное самочувствие опрошенных местных жителей. Социальное самочувствие проявляется в оценках респондентов данных регионов жизни в республике и зависит от их мнения относительно условий сохранения и развития национального родного языка в республике, опыта столкновения с неуважительным дискриминационным отношением к своему национальному и (или) родному языку со стороны других людей в регионе, а также ценности сохранения национального языка и культуры. Анализ строится по результатам социологических опросов, проведенных в республиках Башкортостан, Тува и Калмыкия в период с декабря 2020 г. по январь 2022 г.

Выявлена взаимосвязь между мнением респондентов об условиях изучения и сохранения национального родного языка в республике и общей оценкой качества жизни в этих республиках по сравнению с другими субъектами РФ. Жизнь в регионе проживания оценивается респондентами выше, если они полагают, что условия изучения и сохранения национального родного языка за последние 10 лет улучшились. Респонденты из Тувы, которые ответили, что жители их республики живут лучше, чем жители других регионов страны, выше ценят сохранение национальной культуры и языка в своей республике (в других республиках данная зависимость не подтверждается). Неуважительное отношение к «своему» национальному и (или) родному языку не влияет на оценку респондентами жизни в республике.

Башкиры из Башкортостана, русские из Тувы и калмыки из Калмыкии чаще сталкивались с неуважительным отношением к своему национальному и (или) родному языку, нежели представители других этнических групп из данных республик. В Башкортостане это связано с языковыми спорами и другими недавними социально-политическими событиями в регионе. В Туве это связано с тем, что русских в структуре населения республики гораздо меньше, чем тувинцев. В Калмыкии гораздо чаще других о неуважительном отношении к своему языку заявляют калмыки. На это также влияет и языковая ситуация в республике, и сокращение количества людей, говорящих на национальном калмыцком языке.
Girişimcilik Tutkusu ve Metanet Arasındaki İlişki Üzerine Bir Araştırma
Authors: GÜLBAHAR Yasemin , KARADAL Himmet
Published: June 2022

Bu çalışmanın amacı, girişimcilik tutkusunun yenilikçi davranışlar ve başarısızlık korkusu üzerindeki etkisini belirlemek ve model üzerinde metanetin aracılık rolünü analiz etmektir. Kayseri ilinde faaliyet gösteren OSB’lerdeki girişimci ve yöneticiler araştırmanın örneklemini oluşturmaktadır. Oluşturulan bir anket yardımı ile toplanan verilerin geçerlilik ve güvenilirlik analizleri yapılmıştır. Analiz sürecinde SmartPLS Yapısal Eşitlik Modeli (YEM) tekniği kullanılmıştır. Araştırma bulgularına göre girişimcilik tutkusunun yenilikçi davranışlar üzerinde ve ayrıca metanet üzerinde pozitif etkileri bulunmuştur. Ayrıca araştırma bulguları metanetin, girişimcilik tutkusu ile başarısızlık korkusu ilişkisinde tam aracılık rolüne sahip olduğunu göstermektedir.
Pycnogonida de aguas mexicanas: listado con observaciones en diversidad y ecología
Authors:   Universidad Nacional Autónoma de México, Ramírez-Tello Luis Miguel , Tello-Musi José Luis ,   Universidad Nacional Autónoma de México, López-García Roberto ,   Universidad Nacional Autónoma de México
Published: June 2022

This work is an updated checklist of Mexican Pycnogonida species for both oceans, the Mexican Pacific (PA) and the Gulf of Mexico (GMx). This research was carried out based on the first historical records by Schimkewitsch in 1893 up to the present day. The number of recorded species increased in this study. The total number of species in Mexican oceans is 58, distributed among 19 genera and 10 families. All records were cross-referenced with the original literature, and those found to be questionable were deleted from the checklist. With the data reported in this checklist, an extrapolation of the total number of species was performed using rarefaction curves, thus demonstrating that the recorded species fell well below the projected diversity. The curves showed an estimate of 80 species in the Pacific, whilst 100 species were projected for the Gulf of Mexico. These data indicate that collection efforts and species occurrences nationwide and by waterbody (PA and GMx) are insufficient to describe the diversity of Mexican pycnogonids.
Tindak Tutur Direktif dalam Kumpulan Cerpen Pandawa Kurawa Karya Agus Hiplunudin
Authors: Widodo Mulyanto , Febriyanto Dedi , Fitriyah Lailatul
Published: June 2022

A language is a communication tool used by humans to exchange information between individuals, both in the form of ideas, feelings, and emotions. Every communication process carried out by humans produces speech acts. This study aimed to describe the communication function and strategy for realizing directive speech acts in the collection of short stories Pandawa Kurawa by Agus Hiplunudin. The method used was descriptive qualitative with a pragmatic theory approach. The data source was a collection of Pandawa Kurawa short stories by Agus Hiplunudin. The data was collected through a reading-note technique which was then analyzed descriptively. The research data analysis was carried out by identifying the data, reducing the data, presenting the data, interpreting the data, and concluding the interpretation results. The results showed that the collection of Pandawa Kurawa short stories by Agus Hiplunudin contains a variety of communication functions and strategies for the realization of directive speech acts. The directive speech act was found in communication functions including advising, asking, demanding, ordering, forcing, suggesting, challenging, complaining, encouraging, and asking. Further, the strategies used to realize directive speech acts include a speech strategy without small talk, a speech strategy with positive politeness, and a speech strategy with negative politeness.
Penerapan Model Pembelajaran Berbasis Masalah dalam Pembelajaran Menulis Teks Eksplanasi
Authors: Wati Maulida Laily Kusuma , Haryadi  , Haryati Nas
Published: June 2022

This study was a qualitative descriptive study to describe the design and implementation of problem-based learning models and determine the teachers' obstacles in teaching explanation text of the eleventh grade at SMK Negeri 3 Kudus. The subjects of this study were teachers and eleventh-grade students of SMK Negeri 3 Kudus. The methods of data collection in this study were observation and interview records. The collected data were analyzed using descriptive methods. The research's findings are that teachers arrange problem-based learning models in the lesson plan based on the components of the 2013 curriculum. Secondly, teachers apply problem-based learning models that conform to problem syntax. Third, the obstacles encountered when applying problem-based learning models to teach explanation text came from the teacher's experience in identifying interesting topics and the teacher's ability in the time management needed for learning because this learning model requires a longer time. From the student's point of view, more attention is needed to describe the differences in student abilities. Further, the lack of ability to think critically becomes a challenging obstacle for teachers because the problem-based learning model requires students to be able to think critically.
Membaca Nilai Sufistik dalam Kumpulan Puisi Mencari Sebuah Masjid Editor Husnu Abadi dan Nopri Ahadi
Authors: Shomary Sudirman
Published: June 2022

The anthology of poetry Looking for a Mosque, editors Husnu Abadi and Nopri Ahadi contains 24 titles of poems by well-known Indonesian authors. This work was published as material for a poetry reading competition in commemoration of Islamic Holidays. That is why this anthology of poetry contains many religious themes and Sufistic values. The problem studied is how are the Sufistic values ​​contained in the anthology of the poem Looking for a Mosque? This study uses descriptive analysis and content analysis methods. The results of the study found Sufistic values ​​related to the rituals or worship of Ramadan, Eid al-Fitr, mosques, and the Hajj. Poems about Ramadan worship were embroidered by poets in the poem Malam Qadar by Idrus Tintin, Night of a Thousand Months by Husnu Abadi. Furthermore, Sutardji Calzoum Bachri's Eid-ul-Fitr poem clearly explains about the worship of Ramadan and its night worship and almsgiving can lead one to become His pious servant. The Sufistic value of worship is to draw the servant closer to God, namely Allah SWT (hal taqarrub ilallah). In addition, there are also mystical values ​​related to repenting to God and the low position of servants in front of God Almighty. This anthology of poetry contains maqam wara and maqam zuhud which means the servant's closeness to His Creator because of his special worship and his simple and sincere way of life.
Analisis Kebutuhan: Perangkat Pembelajaran pada Mata Kuliah Praktik Jurnalistik Media Televisi
Authors: Yusandra Titiek fujita , Rahmi Afrini , Satini Ria , Tatalia Ricci Gemarni
Published: June 2022

Practical activities are carried out to prove a concept being studied. Practical activities following 21st-century learning are a form of learning change, initially centered on educators to become student-centered. Learning tools that are designed and planned according to students' needs certainly create interest so that they can build a productive learning environment. This study aimed to see the student's needs for developing learning tools based on interviews and questionnaires distributed to students who took Praktik Jurnalistik media Televisi course. This type of research was Research and Development (R&D). This research was the initial stage of developing learning tools in Praktik Jurnalistik media Televisi course. The needs analysis results obtained data of 46% stating that learning Praktik Jurnalistik media Televisi can improve speaking skills. 39% of students stated that the journalistic practice module requires development; consequently, the journalistic activities' steps and work processes were structured. 37% of students read and used the module as a guide in journalism practice lectures. Furthermore, 42% of students stated the suitability of the activities of 16 meetings with the learning tools and course syllabus.
Analisis Pengaruh Independensi Auditor dan Pendidikan Auditor Terhadap Kualitas Audit Syariah Pada Perbankan Syariah Di Indonesia
Authors: Etika Citra , Liya Ermawati  , Junaini Bustami
Published: June 2022

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh independensi dan pendidikan auditor terhadap kualitas audit syariah pada perbankan syariah. Independensi dan pendidikan auditor sebagai variabel independen. Kualitas audit syariah sebagai variabel dependen. Penelitian ini menggunakan teori dasar yaitu teori perusahaan, teori middle menggunakan teori keagenan dan teori terapannya menggunakan teori kontijensi. Penelitian ini menggunakan data sekunder yaitu laporan keuangan tahunan yang diperoleh dari website resmi bank itu sendiri, dan dapat pula dilihat melalui website resmi Otoritas Jasa Keuangan (www.ojk.go.id) periode 2017-2020. Proses pengambilan sampel dilakukan dengan menggunakan metode purposive sampling, 7 (tujuh) Bank Umum Syariah (BUS) yang dijadikan sampel dan penelitian ini menggunakan analisis regresi linier berganda. Berdasarkan hasil penelitian ini secara parsial variabel independensi auditor berpengaruh signifikan terhadap kualitas audit syariah, pendidikan auditor berpengaruh signifikan terhadap kualitas audit syariah. Selanjutnya secara simultan variabel independensi auditor dan pendidikan auditor berpengaruh signifikan terhadap kualitas audit syariah.
Circumventing Thermodynamics to Synthesize Highly Metastable Tin(II) Perovskites: Nano Eggshells of SnHfO3
Authors: Gabilondo Eric , Newell Ryan , Chestnut Jessica , Weng James , Jones Jacob , Maggard Paul
Published: June 2022

Sn(II)-based perovskite oxides, being the subject of longstanding theoretical interest for the past two decades, have been synthesized for the first time with a nanoshell approach. All past reported synthetic attempts had been rendered impotent by the extremely high metastabilities, i.e., thermodynamic instability. Herein, a soft topotactic exchange of Sn(II) cations into Ba-containing perovskites is demonstrated to successfully yield ~20 nm thick shells of Sn(II) perovskites, i.e. SnHfO3. Additionally, highly pure SnHfO3 was obtained for the first time as nano-eggshell morphologies that circumvent the intrinsic ion-diffusion limits occurring at a low reaction temperature of 200 oC. In summary, the high metastability of the Sn(II) perovskites is shown to be overcome by leveraging the high cohesive energies of the reactants, the exothermic formation of a stable salt side product, and a shortened diffusion pathway for the Sn(II) cations. The new approach finally provides an effective solution to surmounting highly intractable synthetic barriers, and which can be the key to unlocking the door to many other new metastable oxides.
From descriptors to intrinsic fish toxicity of chemicals: an alternative approach to chemical prioritization
Authors: Samanipour Saer , O'Brien Jake , Reid Malcolm , Thomas Kevin , Praetorius Antonia
Published: June 2022

Most chemicals present in the human and environmental exposome are structurally unknown (i.e. ≤ 1%). The European Chemicals Agency (ECHA) and US Environmen- tal Protection Agency (EPA) have listed approximately 800k chemicals that must be further investigated for their potential environmental and/or human health risk. A sig- nificant number of these chemicals have large enough global volumes of consumption (e.g. industrial and agrochemical) to reach the limits of detection of our analytical chemistry methods and may be toxic. In this study we present a supervised classification model that directly connects the molecular descriptors of chemicals to their toxicity. As a proof of concept we used 907 experimentally defined LC50 values for acute fish toxicity. Our classification model explained ≈ 90% of variance in our data for the training set and ≈ 80% for the test set. Direct comparison of our classification model with the conventional strategy (i.e. QSAR regression models) resulted in a 5 fold decrease in the wrong chemical categorization for our model. This optimized model was employed to predict the toxicity categories of ≈ 32k chemicals (from the Norman SusDat). Finally, a comparison between the model based applicability domain (AD) vs the training set AD was performed, suggesting that the training set based AD is a more adequate way to avoid extrapolation when using such models. The better performance of our direct classification model compared to conventionally employed QSAR methods, makes this approach a viable tool for hazard identification and risk assessment of chemicals.
Solid-phase synthesis of cereblon-recruiting selective histone deacetylase 6 degraders (HDAC6 PROTACs) with anti-leukemic activity
Authors: Sinatra Laura , Yang Jing , Schliehe-Diecks Julian , Dienstbier Niklas , Voigt Melina , Gebing Philip , Bachmann Luisa M. , Sönnichsen Melf , Lenz Thomas , Stühler Kai , Schöler Andrea , Borkhardt Arndt , Bhatia Sanil , Hansen Finn K.
Published: June 2022

Selective histone deacetylase 6 (HDAC6) inhibitors are useful tools to study the function of the second catalytic domain of HDAC6, but they cannot interfere with (non)-enzymatic functions of HDAC6, which are mediated via the first catalytic domain or the ubiquitin binding domain. In this work, we utilized the proteolysis targeting chimera (PROTAC) technology to achieve the chemical knock-down of HDAC6. Two series of cereblon-recruiting PROTACs were synthesized via a solid-phase parallel synthesis approach, which allowed the rapid preparation of two HDAC6 degrader mini libraries. The PROTACs were either based on an unselective vorinostat-like HDAC ligand or derived from a selective HDAC6 inhibitor. Notably, both PROTAC series demonstrated selective degradation of HDAC6 in leukemia cell lines. The best degraders from each series (denoted A6 and B4) were capable of degrading HDAC6 via ternary complex formation and the ubiquitin−proteasome pathway, with DC50 values of 3.7 and 13.3 nM, respectively. Moreover, HDAC6 degradation of A6 and intracellular (nucleocytoplasmic) localization of a fluorescein-labelled PROTAC (A7) was determined by fluorescence microscopy. PROTAC A6 demonstrated promising antiproliferative activity via inducing apoptosis in myeloid leukemia cell lines. These findings highlight the potential of this series of degraders as effective pharmacological tools for the targeted degradation of HDAC6.
Minimum free energy pathways with the nudged elastic band method in combination with a QM-MM Hamiltonian
Authors: Semelak Jonathan A. , Foglia Nicolás O. , Estrin Darío A.
Published: June 2022

The optimization of minimum free energy pathways (MFEP) is one of the most widely used strategies to study activated processes. For chemical reactions, this requires the use of quantum mechanics. Using quantum mechanics molecular mechanics (QM- MM) Hamiltionians allows the simulation of reactive processes in complex environments by treating with quantum mechanics only the chemically relevant part of the system. However, even within this approximation, the affordable simulation lenghts of QM-MM simulations is in general, quite limited. Free energy methods based on the sampling of the potential energy surface require long simulations times to provide converged and accurate results. As consequence, the combination of QM-MM methods and free energy calculations is computationally expensive. Moreover, the user usually needs to perform an a priori selection of the reaction coordinate. This may be not trivial for the general case. One of the most established methods for finding potential energy profiles without selecting a reaction coordinate is the nudged elastic band method (NEB). In this work, we used the extension of this method to the exploration of the free energy surface for finding MFEP (FENEB). We present and apply to reactive systems an improved version of the basic optimization scheme of FENEB that increases its robustness, and is based on decoupling the optimization of the band in the perpendicular direction to the band, from the optimization of the tangential direction. In each optimization step, a full optimization with the spring force is performed, in order to keep the images evenly distributed. Additionally, we evaluate the influence of sampling in the quality of the optimized MFEP and free energy barrier computed from it. We show and discuss that the FENEB method provides a good estimation of the reaction barrier even with relatively short simulations lenghts and that it scales better than umbrella sampling both with simulation lenght and with dimensionality. Overall, our results support that the combination of QM-MM methods and the FENEB provides an adequate tool study chemical processes in complex environments.
Comparison and risk assessment of trace metal content in factory-farmed broiler and free-range chicken meat sold in Laguna, Philippines
Authors: Estrella Monique , Samson Aileen Fritz , Espiritu Rafael
Published: June 2022

Chicken meat consumption remains high in the Philippines, and consequently, annual chicken production has risen steadily over the years. Although most of the chicken meat available in the market are sourced from factory farms, there has been growing popularity of free-range chicken production, largely driven by its perceived health benefits and sanitation concerns in factory farms, among others. In this work, we aimed at comparing the trace metal (copper, iron, lead, manganese, and zinc) content of free-range and factory-farmed broiler chicken meat that are being sold in Laguna, Philippines. The samples were subjected to acid digestion and analysis was done using atomic absorption spectrometry. Results showed an average concentration between 0.17 – 0.24 mg/kg, 2.22 – 2.34 mg/kg, 0.12 – 0.15 mg/kg, 0.95 – 1.32 mg/kg, and 1.81 – 1.96 mg/kg for copper, iron, lead, manganese, and zinc, respectively. Statistical analysis using one-way ANOVA and Tukey multiple comparison test (p < 0.05) showed no significant differences in the trace metal content of free-range and factory-farmed chicken meats, suggesting that in terms of the levels of these trace metals, not much differentiates the two varieties. Analysis of the health hazards, reported as target hazard quotient (THQ) and hazardous index (HI), associated with the consumption of the said chicken breast meat indicated no potential health risks.
Effect of Bacillus and Pseudomonas biofilms on the corrosion behavior of AISI 304 stainless steel
Authors: Wadood Hafiz Zeeshan , Rajasekar Aruliah , Farooq Ameeq , Deen Kashif Mairaj
Published: June 2022

In this research work, the corrosion tendency of stainless steel (SS 304) caused by the Pseudomonas aeruginosa ZK (PA-ZK) and Bacillus subtilis S1X (BS-S1X) bacterial strains is investigated. The topographical features of the biofilms and SS304 substrate achieved after 14 days of incubation at 37 °C were examined by scanning electron microscopy (SEM). Fourier Transform Infrared Spectroscopic (FTIR) analysis of the extracellular polymer substance (EPS) was also carried out to estimate the chemical composition of the biofilm. Electrochemical Impedance Spectroscopy (EIS) and Tafel Polarization test methods were applied to understand the in-situ corrosion tendency of the SS304 in the presence of PA-ZK and BS-S1X strains. Compared to the biofilm produced by the PA-ZK, the EPS in the BS-S1X containing bacteria was porous and non-uniform as revealed in the SEM analysis. The improved hydrophobicity and uniformity of the PA-ZK containing biofilm retarded the corrosion of the underlying SS304 sample. Appreciably large resistance of the PA-ZK biofilm (~ 6.04 kΩ-cm2) and hindered charge transport (11.12 kΩ-cm2) was evident from the EIS analysis. In support of these results, a large cathodic Tafel slope (0.2 V/decade) and low corrosion rate (1.69 µA/cm2) were corroborated to the inhibitive properties of the PA-ZK containing biofilm. However, the formation of porous biofilm and non-homogeneity of the EPS layer produced by the BS-S1X bacteria enhanced localized corrosion as evident from the low charge transfer resistance, a high corrosion rate and formation of pits on the surface of SS304 were comparable to the surface features obtained after exposure to the controlled medium. These results highlighted the poor corrosion inhibitive properties of the BS-S1X bacteria compared to the PK-ZK bacterial strain.
Retrospective analysis of patients with diabetes mellitus type 2 and acute myocardial infarction
Authors: Bardymova Tatiana P. , Tsyretorova Seseg S. , Donirova Oyuna S.
Published: June 2022

Background. Acute myocardial infarction (AMI) in patients with type 2 diabetes mellitus (T2DM) is characterized by a severe course and unfavorable clinical outcomes. Accumulating information, which characterize the features of the development of AMI depending on the degree of carbohydrate metabolism disorders (CMD).
Aim. To conduct a retrospective analysis of medical records with an assessment of the clinical profiles of the patients with T2DM and AMI.
Materials and methods. A retrospective analysis of medical records of patients in the acute period of myocardial infarction over a five-year period was carried out. The exclusion criteria were: unstable or stable angina pectoris. The average values and standard deviations (MSD) were calculated. Comparison of quantitative variables between groups was carried out using the Student's t-test. Absolute (n) and relative (%) values were calculated to describe qualitative data. The value p0.05 was used as the level of statistical significance.
Results. The total number of medical records is 7618, of them with AMI 2337 cards, of which 1114 (48%) patients with T2DM, type 1 diabetes mellitus, impaired glucose tolerance/impaired fasting glycemia (IGT/IFG) and AMI, as well as 1223 (52%) patients with AMI without CMD. Among patients with AMI, patients with T2DM and AMI accounted for 23%. Gender differences with female dominance were registered in the group of T2DM and AMI (63%), men dominated among patients with AMI without CMD. In the groups of T2DM and AMI, IGT/IFG and AMI, AMI without CMD, women were older than men (p0.05%). In patients with T2DM and AMI, compared with patients with AMI without CMD, repeated AMI and high mortality are more often registered. The presence of diabetes was associated with a higher incidence of concomitant diseases and the presence of severe complications of the disease.
Conclusion. Clinical features of AMI in patients with T2DM are represented by gender-age parameters, characteristics of concomitant pathology and the nature of complications of acute ischemia, the frequency of repeated AMI with an increased risk of adverse outcomes.
IgM-enriched immunoglobulin improves colistin efficacy in a pneumonia model by Pseudomonas aeruginosa
Authors: Cebrero-Cangueiro Tania , Labrador-Herrera Gema , Carretero-Ledesma Marta , Herrera-Espejo Soraya , Álvarez-Marín Rocío , Pachón Jerónimo , Cisneros José Miguel , Pachón-Ibáñez María Eugenia
Published: June 2022

We evaluated the efficacy of ceftazidime or colistin in combination with polyclonal IgM-enriched immunoglobulin (IgM-IG), in an experimental pneumonia model (C57BL/6J male mice) using two multidrug-resistant Pseudomonas aeruginosa strains, both ceftazidime-susceptible and one colistin-resistant. Pharmacodynamically optimised antimicrobials were administered for 72 h, and intravenous IgM-IG was given as a single dose. Bacterial tissues count and the mortality were analysed. Ceftazidime was more effective than colistin for both strains. In mice infected with the colistin-susceptible strain, ceftazidime reduced the bacterial concentration in the lungs and blood (−2.42 and −3.87 log10 CFU/ml) compared with colistin (−0.55 and −1.23 log10 CFU/ml, respectively) and with the controls. Colistin plus IgM-IG reduced the bacterial lung concentrations of both colistin-susceptible and resistant strains (−2.91 and −1.73 log10 CFU/g, respectively) and the bacteraemia rate of the colistin-resistant strain (−44%). These results suggest that IgM-IG might be useful as an adjuvant to colistin in the treatment of pneumonia caused by multidrug-resistant P. aeruginosa.
The Story of a Prophetic Ḥadīth on Mushrooms: Transmission and Commentary
Authors: ÖZKAN Halit
Published: June 2022

This study analyzes prophetic ḥadīths about mushrooms, particularly the ḥadīth that we refer to as “the mushroom ḥadīth.” The ḥadīth reads, “The mushroom is part of manna and its water is a cure for the eyes.” The beginning of the article explains the reasons the Prophet uttered these ḥadīths. Since companions held negative opinions about mushrooms—some of which can be traced back to Jāhiliyya—the Prophet intended to correct them. Mushrooms were familiar in Arab culture, hence the existence of negative opinions about them. As a widely encountered food among Arabs both before and after the emergence of Islam, information on identifying various species of mushrooms, making distinctions between poisonous and non-poisonous species, cooking methods, and references in stories and poems are plentiful and easily accessible.
Tefsir Geleneğinde Rivâyet
Authors: DİNÇ Ömer
Published: June 2022

Tefsir faaliyetinin başladığı zaman diliminden günümüze kadar geçen süreçte tefsire dair farklı tasniflerin ve ayırımların yapıldığı bilinmektedir. Klasik dönemde bazı emareleri görülse de özellikle çağdaş dönemde tefsir tarihine dair yapılan çalışmalarda tefsirler genel olarak “rivayet” ve “dirayet” şeklinde isimlendirilmektedir. Yapılan bu tanımlama ve kategorik bakış açısı tefsir tarihindeki eserlerin mahiyetini tam olarak yansıtamamakta, çalışmaların hususiyetlerine yönelik eksik bir yaklaşımı beraberinde getirmektedir. Bilhassa “rivayet tefsiri” ifadesinin tefsir geleneğinde nasıl bir alana tekabül ettiği, bunun tam olarak ne ifade ettiği hususu tartışmalı bir görünüm arz etmektedir. Bu çerçevede tefsirde “rivayet” kavramının ne anlama geldiği, keyfiyetine dair ortaya çıkan yaklaşımları, tefsirde rivayetin değeri ve problemli olduğu alanları vb. meseleleri ayrıntılı ele alan bir çalışma Prof. Dr. Ali Karataş tarafından kaleme alınmıştır. Tefsir Geleneğinde Rivâyet adlı eserde Karataş, genel tefsir müktesebatı bağlamında “rivayet” unsurunun bütün yönlerini ele almakta, tefsir çalışmaları için “rivayet”in merkezî bir konumda olup olmamasını araştırmakta, hadis ile tefsir sahasındaki “rivayet” algılarını incelemektedir.
Classificação de Áreas Suscetíveis à Incêndios na Bacia do Córrego d’Antas, Nova Friburgo (RJ): uma proposta metodológica
Authors: Bolsas Letícia , Facadio Ana Carolina , Coelho Netto Ana Luiza
Published: June 2022

Os incêndios são fenômenos naturais que têm se tornado cada vez mais recorrentes em virtude de uso intensivo da terra e das mudanças climáticas em curso. No município de Nova Friburgo, os meses mais secos chegam a ultrapassar 400 ocorrências de incêndios. A análise espacial da suscetibilidade à ocorrência de incêndios permite compreender a trajetória do fogo, sendo uma ferramenta que pode auxiliar no planejamento e gestão territorial para a prevenção e combate desse fenômeno. Nesse contexto, o presente trabalho propõe uma metodologia para identificação de áreas suscetíveis à ocorrência de incêndios em nível de detalhe (entre 1:10.000 e 1:5.000), tomando a bacia do Córrego d’Antas (53 km²) como área piloto. A carta de suscetibilidade é o resultado da integração das cartas do potencial de detonação e potencial de propagação. A carta de suscetibilidade demonstrou que 45% da área da bacia está classificada como alta suscetibilidade e que 76% da área queimada ocorreu nessa classe. A sobreposição dos incêndios georreferenciados no período de 2004 a 2010 ressaltou a importância de se levar em conta as condições de detonação e propagação, assim como as relações de vizinhança entre áreas com diferentes potenciais de suscetibilidade aos incêndios.Palavras-chave: suscetibilidade de terreno, fogo, detonação, propagação, encostas montanhosas Classification of Fire Susceptible Areas in the Córrego d’Antas Basin, Nova Friburgo (RJ): a methodological proposal A B S T R A C TFires are natural phenomena that have become increasingly recurrent due to intensive land use and ongoing climate changes. In the municipality of Nova Friburgo, the driest months come to surpass 400 occurrences of fires. The spatial analysis of the susceptibility to the occurrence of fires allows us to understand the trajectory of fire, being a tool that can help with territorial planning and management for the prevention and combat of this phenomenon. In this context, the present work proposes a methodology for identifying areas susceptible to fire occurrence at the level of detail (between 1:10,000 and 1:5,000), taking the Córrego d'Antas basin (53 km²) as a pilot area. The susceptibility map is the result of the integration of the detonation potential and propagation potential maps. The susceptibility map showed that 45% of the basin area is classified as high susceptibility and that 76% of the burned area occurred in this class. The overlapping of georeferenced fires in the period 2004 to 2010 highlighted the importance of taking into account the detonation and propagation conditions, as well as the neighborhood relationships between areas with different potentials of susceptibility to fires.Keywords: terrain susceptibility, fire, trigger, fire spread, mountainous slopes.
Análise da Qualidade da Mobilidade e Acessibilidade Urbana do Transporte Coletivo na Cidade de Juiz de Fora - MG
Authors: Oliveira Amanda Rodrigues da Silva , Salomão Mariana de Athayde , Barbosa Maria Teresa Gomes
Published: June 2022

As vias urbanas e suas instalações são fundamentais para o desenvolvimento social, econômico e sustentável das cidades, auxiliando os meios de transportes e a mobilidade urbana, motivo pelo qual devem ser funcionais e proporcionar qualidade e segurança aos usuários. O objetivo do presente trabalho é identificar os aspectos da infraestrutura que impactam na qualidade do serviço do transporte urbano coletivo, inserindo-se, nesse contexto, a vistoria das manifestações patológicas nos pavimentos asfálticos, bem como a qualidade das paradas de ônibus no que se refere às exigências dos usuários. Sendo assim, efetuou-se uma revisão bibliográfica acerca do tema proposto e uma minuciosa investigação em campo, nas principais vias localizadas na cidade de Juiz de Fora - MG, a fim de se obter as particularidades dos pontos de ônibus e das vias de acesso nas 8 principais regiões da cidade, a saber: norte, noroeste, central, oeste, leste, sul, nordeste e sudeste. Constatou-se, no estudo efetuado, a necessidade de ressaltar a relevância dos serviços de manutenção e conservação dos pavimentos e dos pontos de ônibus a fim de garantir a qualidade e segurança dos usuários, melhorando a mobilidade urbana do município e, consequentemente, contribuir para a consolidação do conceito de cidade sustentável.Palavras-chave: Mobilidade urbana. Via pública. Manifestações patológicas. Cidades sustentáveis. Analysis of the Quality of Mobility and Urban Accessibility of Public Transport in the City of Juiz de For a - MGABSTRACTUrban roads and their facilities are fundamental for the social, economic and sustainable development of cities, helping the means of transport and urban mobility, which is why they must be functional and provide quality and safety to users. The objective of the present work is to identify the aspects of the infrastructure that impact on the quality of the service of public urban transport, inserting, in this context, the inspection of pathological manifestations on asphalt pavements, as well as the quality of bus stops with regard to the requirements of users. Therefore, a bibliographic review was carried out on the proposed theme and a thorough investigation in the field, in the main roads located in the city of Juiz de Fora (MG), in order to obtain the particularities of bus stops and access roads. in the 8 main regions of the city, namely: north, northwest, central, west, east, south, northeast and southeast. It was found, in the study carried out, the need to emphasize the relevance of maintenance and conservation services of pavements and bus stops in order to guarantee the quality and safety of users, improving the urban mobility of the municipality and, consequently, contributing to the consolidation of the concept of sustainable city.Keywords: Urban mobility. Public highway. Pathological manifestations. Sustainable cities.
Análise de parâmetros da qualidade da água no lago Descoberto no Distrito Federal, por meio de imagens do satélite Sentinel –2B
Authors: Magalhães Ivo Augusto Lopes , De Souza Ana Carolina Pereira , Minoti Ricardo Tezini , Gomes Lenora Nunes Ludolf
Published: June 2022

O propósito deste estudo foi analisar os parâmetros de qualidade de água no reservatório do lago Descoberto, no Distrito Federal por meio de imagens Sentinel-2 para o ano de 2018. Utilizou-se os dados da CAESB diagnosticados nos meses de abril e maio, acerca da qualidade da água no reservatório para comparar com as imagens disponibilizadas pelo satélite Sentinel -2. Selecionou-se as bandas com as faixas espectrais mais adequadas para a análise de cada parâmetro da água no reservatório e todas as técnicas de geoprocessamento foram aplicadas no software ArcGIS 10.5. De posse das imagens processadas utilizou-se os resultados para se estabelecer uma escala de classificação para monitoramento dos parâmetros de qualidade hídrica. A proximidade espectral dos valores de nível de cinza para as bandas do satélite Sentinel-2 nos meses amostrados comprovou que não houve uma mudança brusca ou até mesmo eutrofização no lago do Descoberto no período temporal analisado. A aplicação das técnicas de sensoriamento remoto para auxílio e análise de parâmetros da qualidade da água apresentaram resultados coerentes, demonstrando ter aplicabilidade para estudos de monitoramento de transparência, clorofila-a e turbidez no reservatório e corpos hídricos.Palavras-chave: Qualidade da água; reservatório; sensoriamento remoto. Analysis of parameters of water quality in the Descoberto lake in the Federal District, through images of the Sentinel -2B satellite A B S T R A C TThe purpose of this study was to analyze the water quality parameters in the Descoberto lake reservoir, in the Federal District, using Sentinel-2 images for the year 2018. CAESB data diagnosed in April and May, about of the water quality in the reservoir to compare with the images provided by the Sentinel -2 satellite. The bands with the most appropriate spectral bands were selected for the analysis of each water parameter in the reservoir and all geoprocessing techniques were applied in the ArcGIS 10.5 software. In possession of the processed images, the results were used to establish a classification scale for monitoring the water quality parameters. The spectral proximity of the gray level values for the bands of the Sentinel-2 satellites in the sampled months proved that there was no sudden change or even eutrophication in the Descoberto lake in the analyzed period. The application of remote sensing techniques to aid and analyze water quality parameters showed coherent results, demonstrating their applicability for monitoring studies of transparency, chlorophyll-a and turbidity in the reservoir and water bodies.Keywords: Water quality; reservoir; remote sensing.
Impact of COVID-19 on drug markets, use, harms and drug services in Europe
Authors: Pirona Alessandro , Matias João , Montanari Linda , Skarupova Katerina , Ferri Marica , Giraudon Isabelle , Mounteney Jane , Sleiman Sandrine , Natoniewska Katarzyna , Guarita Bruno , Vandam Liesbeth , Surmont Tim , Griffiths Paul
Published: June 2022

Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets have been impacted, as have the drug services established to respond to drug-related problems. Since the start of the pandemic in March 2020, the European Monitoring Centre for Drugs and Drug Addiction instigated three rapid assessment studies to identify the initial impact and implications of COVID-19 on drug markets, use, harms and drug services in the community and in prisons. Findings from these studies revealed that the pandemic and associated health prevention measures implemented by the countries impacted drug markets and use differently depending on the different periods and events throughout the pandemic, but also according to particular drugs or user characteristics. Most drug services remained operational throughout the pandemic in order to assure continuity of care. This was achieved by innovation and adaptation of their services, especially during the different lockdown periods. Thus, the results from these rapid assessments provide a glimpse into new developments in the drugs field across European countries emerging both during and in response to the pandemic, and which could have important implications for the future.
The impact of the COVID-19 pandemic on drug demand and supply in Estonia
Authors: Abel-Ollo Katri , Kivila Margo , Kurbatova Aljona , Ovsjannikova Svetlana
Published: June 2022

The COVID-19 pandemic has changed the world and imposed restrictions and rules that democratic countries could not have foreseen. The global health and social care system was put under enormous pressure, and preventing it from a total collapse became the primary objective. This paper looks at how the pandemic affected the illicit drug market, people who use drugs and services designed to support and help them. Based on the available studies and administrative statistics from 2019 and 2020, illicit drug use and need for services remained the same despite the pandemic. Services quickly adopted new operating rules and became available for the target group. There is ample evidence that in some cases illicit drug use (e.g. cannabis) even gained in popularity as a coping method for anxiety and stress. The drug supply fell only temporarily due to the COVID-19, to which it quickly adapted through new IT and crypto possibilities (dark web).
The COVID-19 impact on the illegal retail drugs market in Latvia and drug use patterns
Authors: Zīle-Veisberga Agnese
Published: June 2022

The purpose of the study is to explore how the COVID-19 situation has affected the illegal retail market and drug use patterns. Three research questions were formulated: 1) What has been the COVID-19 impact on the retail illegal drugs market? 2) How has the pandemic impacted drug use patterns? 3) Are there trends that presumably would have an impact after COVID-19? The mixed method with an explanatory sequential design was used in the analysis. At the first stage of the analysis all available quantitative data such as routine administrative data and data from regular surveys were analysed and triangulated. The results of quantitative analysis were supplemented by qualitative data, such as reports. The analysis does not suggest changes on the retail market, except for some increase in cannabis cultivation during the first wave in 2020 and a slight decrease in MDMA prevalence on the market in 2021. Drug use patterns are similar to those before the pandemic, with some exceptions that might indicate more cannabis and MDMA use among frequent users.
Determining Audit Quality in the Accounting Profession with Audit Ethics as a Moderating Variable
Authors: Hermawan Sigit , Rahayu Duwi , Biduri Sarwenda , Rahayu Ruci Arizanda , Salisa Nur Amalina Nisfa
Published: June 2022

Obtaining information about a companyâ€™s financial statements has become increasingly important. Thus, highly skilled and expert public accountants are required who can execute their tasks following ethical standards. This study investigates the effects of audit professional skepticism and auditor expertise and integrity on audit quality in the accounting profession, with auditor ethics as the moderating variable. The study sample consisted of 65 auditors working in 14 public accounting firms in Surabaya, Indonesia. Data were collected through questionnaires and then analyzed using the SmartPLS approach. Results indicated that audit professional skepticism and auditor expertise and integrity positively influence audit quality. On one hand, auditor expertise, which is moderated by auditor ethics, positively influences audit quality. On the other hand, audit professional skepticism and integrity, which are moderated by auditor ethics, do not influence audit quality. The findings suggest that auditors must further improve their compliance with ethical standards to strengthen their integrity, which in turn, enables them to produce good audit quality. Furthermore, auditors must always strive to increase their professional skepticism and expertise.