bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and characterization of quinolone-resistant Escherichia coli isolated from retail raw beef and poultry meat in Egypt
Authors: Ibrahim Dina , Awad Amal , Younis Gamal
Published: October 2023

Objective: The goal of this study was to look at quinolone-resistant (QR) Escherichia coli (E. coli) from retail beef and poultry meat in Egypt by looking at the QR mechanisms in the resistant strains.
Materials and Methods: In total, 120 samples of raw poultry meat (n = 60) and beef meat (n = 60) were purchased from Mansoura retail stores between January and March 2021, and evaluated microbiologically for E. coli. Then, an antimicrobial sensitivity test was applied to all isolates. The prevalence of QR E. coli with concern for the QR determinants, including quinolone resistance-determining regions (QRDRs) mutations, the plasmid-mediated quinolone resistance gene (PMQR), and the efflux pump activity were determined.
Results: The total prevalence of E. coli was 34.2% (41/120). Noticeably, the prevalence of E. coli in poultry meat (40%, 24/60) was higher than that of beef (28%, 17/60). All strains were assessed for their antimicrobial susceptibility using the disc diffusion technique; the highest rate of resistance (100%) was displayed to clindamycin and cefuroxime, followed by ampicillin (97.6%), doxycycline (92.7%), amoxicillin-clavulanate (92.7%), nalidixic acid (NA) (80.5%), sulfamethoxazole/trimethoprim (70.7%), chloramphenicol (63.4%), gentamicin, and azithromycin (58.5% each). Multiple antimicrobial resistance (strains resistant to three or more antimicrobial classes) was displayed by 97.6% of E. coli isolates. Regarding QR, 37 isolates could resist at least one of the examined quinolones. Regarding PMQR genes, qnrS was determined in 70% (7/10) of QR E. coli, while qnrA, qnrB, and qnrD were not identified. While the mutations determined regions of QR in the resistant E. coli isolates, S83L was the most prevalent in gyrase subunit A either alone or combined with D87N and D87Y, and three isolates of QR E. coli isolates revealed a topoisomerase IV subunit mutation harboring S80I. 20% of the isolates displayed efflux activity, as NA showed a considerable difference between its zones of inhibition.
Conclusion: The high prevalence of antimicrobial-resistant E. coli, with concern for QR strains harboring different resistance mechanisms in poultry meat and beef, threatens the public’s health. Thus, standard manufacturing procedures and adequate hygiene conditions must be followed in all phases of meat preparation, production, and consumption, and public knowledge should be improved.
Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years
Authors: Gholami Mohammad , Derakhshanfar Amin , Gholami Tahereh
Published: October 2023

Objective: This study aimed to evaluate a new drug combination for small ruminant respiratory diseases to find a better treatment protocol for the potential replacement of older methods.
Materials and Methods: A total of 6,886 animals received common respiratory disease therapies out of 15,845 animals that had respiratory disorders. The new combination therapy technique treated the remaining animals (8,968). The animals were given an oral suspension of triclabendazole or levamisole at an initial dosage of 0.2 ml/kg body weight (BW). The following day, 0.2 mg/kg of 1% ivermectin was subcutaneously administered. Then, on the third and fifth days of treatment, a subcutaneous injection of 30 mg/kg BW of florfenicol (30%) was administered. The survival and recovery rates for both groups were tracked throughout a 6-month period of observation. Postmortem and histopathological signs were also assessed.
Results: In the group of the novel combination therapy, group A, clinical, postmortem, and his¬topathological signs were significantly reduced compared to group B. Clinical signs and mortality in group A were 90% and 93% lower than in group B, respectively. Animals that received the new combination therapy were healed of their disease and stayed immune for 6 months.
Conclusion: This novel therapy demonstrated significant efficacy against respiratory diseases in a 10-year field study. The paper proved that the protocol introduced could be a new therapeutic approach.
Prevalence and identification of caprine pasteurellosis in pneumonic goats in Bangladesh
Authors: Rahman Md , Akther Sonia , Alam Md , Hassan Md , Sarkar Md , Ali Md , Giasuddin Md , Ahmed Sadek
Published: October 2023

Objective: This research aimed to assess the prevalence of caprine pasteurellosis, isolate and identify pasteurellosis (Mannheimia haemolytica and Pasteurella multocida) in pneumonic goats, and discover the main bacterial cause of pneumonia.
Materials and Methods: One hundred and five samples (94 nasal swabs and 11 lung tissues) from goats suspected of having pneumonia were taken and transferred aseptically to the laboratory. Following the processing of the collected samples, Pasteurella spp. was isolated with the aid of plate culture methods. Biochemical characteristics were used to identify all bacterial isolates, which were then verified by polymerase chain reaction (PCR). Antimicrobial susceptibility testing was also carried out to evaluate the sensitivity profiles of various antibiotics. The Pasteurella hae¬molytica serotype-specific antigen (PHSSA) gene was used to identify isolates of M. haemolytica, and the KMT1 gene was used to identify isolates of P. multocida.
Results: From the 105 clinically suspicious samples, 51 (48.57%) were identified to be Pasteurella spp. through bacteriological testing and also by PCR targeting the 16S rRNA gene. Of these, 47.87% (45/94) were nasal swabs, and 54.55% (6/11) were lung tissues. Among confirmed sam¬ples, 70.59% (36/51) were identified as M. haemolytica, and 29.41% (15/51) were identified as P. multocida. Resistance to tetracycline, streptomycin, oxytetracycline, gentamicin, and ceftriax¬one was found in 50%–83% of the isolates. In addition, PCR identified the PHSSA and KMT1 genes from isolates of P. multocida and M. haemolytica, respectively.
Conclusion: The present study revealed that M. haemolytica and P. multocida primarily caused pasteurellosis in pneumonic goats in Bangladesh. However, when treating these animals, the proper choice of antimicrobials should be made to control this disease.
Antimicrobial resistance patterns of Staphylococcus aureus isolated from apparently healthy pet cats of Bangladesh
Authors: Das Shanta , Kabir Ajran , Chouhan Chandra , Shahid Md , Habib Tasmia , Kobir Md , Hossain Md , Rahman Marzia , Nazir K
Published: October 2023

Objective: This study sought to determine the occurrence, molecular identification, antimicrobi¬al-resistant trends, and gene distribution of Staphylococcus aureus in pet cats and their owners’ hand swabs.
Materials and Methods: From different places and clinics in Mymensingh and Dhaka, 168 pet cat samples and 42 hand swab samples from cat owners were obtained. The organisms were scruti¬nized by assessing the outcomes using conventional and molecular techniques. The disc diffusion technique was applied to find the resistance pattern against 12 antibiotics, and genes were dis¬covered by targeting specific genes using PCR.
Results: The occurrence of pathogenic S. aureus in pet cats was 7.74%, while it was 9.50% in pet owners’ hand swabs, and 25.0% of the pet owner’s hand swabs contained these genes. Staphylococcus aureus was utterly resistant to amoxicillin, ampicillin, cefixime, erythromycin, and imipenem in both pet cat and hand swabs of pet owner samples. All S. aureus isolates had a multi¬drug-resistant phenotype, and 1 from pet cats (O19) and 1 from pet owner hand swabs (H9) were resistant to all 12 antibiotics in the 7 antimicrobial classes. Several antibiotic-resistance genes were detected by PCR.
Conclusion: The study confirmed multidrug-resistant pathogenic S. aureus in pet cats and their owners in Bangladesh, indicating a major health risk to both people and cats. Thus, a holistic and integrated one-health approach between veterinary and medical specialists is needed to mitigate the global distribution of these zoonotic antibiotic-resistant S. aureus strains.
Isolation, adaptation, and characterization of lumpy skin disease virus from cattle in Bangladesh
Authors: Pervin Sumaiya , Ahamed Md , Chouhan Chandra , Jahan Md , Ahmed Rony , Nazir K , Siddique Mahbubul , Rahman Md , Kafi Md , Rahman Md
Published: October 2023

Objective: The research aimed to isolate, adapt to cell culture, and characterize the lumpy skin disease virus (LSDV) from clinically infected cattle in Bangladesh.
Materials and Methods: From September 2019 to June 2020, 37 skin nodules and skin swabs were aseptically collected from afflicted cattle in the outbreak regions of Jhenaidah and Kishoreganj in Bangladesh. The LSDV was isolated from embryonated specific pathogen-free (SPF) chicken eggs along the chorioallantoic membrane (CAM) route and the Vero cell line after several blind pas¬sages. The viral attachment protein was targeted for molecular detection using polymerase chain reactions (PCR). For phylogenetic analysis, PCR-positive products were partially sequenced.
Results: The virus was evident in the cell line, showed cytopathic effects after the 13 blind pas¬sage, and on the CAM of SPF chicken eggs, exhibited thickening of the CAM with pock-like lesions. A total of 12 samples (32.43%) tested positive for LSDV by PCR. Phylogenetic analysis of the present isolates (accession numbers MN792649 and MN792650) revealed 100% similarity with strains from India (MN295064), Kenya (AF325528, MN072619, KX683219), Greece (KY829023), Serbia (KY702007), and Kazakhstan (MN642592); moreover, 99.43% to 100% similarity to the sheep pox virus.
Conclusion: Partially sequenced LSDV was developed as a vaccine seed and was first isolated in Bangladesh and characterized at the molecular level.
Evaluation of the IVF success in frozen-thaw in vitro fertilization cycles in terms of endometrial thickness
Authors: Demir Mustafa , Guven Davut , Ersoy Ilhami
Published: October 2023

The aim of this research was to analyze the link between endometrial thickness (EMT), as measured during progesterone administration, and the results observed in individuals who underwent frozenthawed embryo transfer. A retrospective analysis was performed on 233 hormone replacement therapy (HRT) methods of endometrial preparation in frozen-thawed embryo transfer (FET) cycles (HRT-FET). HRT-FET cycles that were conducted between January 2021 and December 2022 at the In vitro fertilization (IVF) Clinic of 19 May University Medical Faculty Training and Research Hospital. The patients' age, infertility duration, basal follicle-stimulating hormone (FSH) level, body mass index (BMI), number and day of embryos transferred, and pregnancy rates were evaluated. Endometrial thickness was measured using transvaginal ultrasound (TV USG) on the day of progesterone administration. The endometrial thickness of patients who achieved clinical pregnancy and those who did not were analyzed. No significant differences in demographic factors were found between the groups in terms of age, infertility duration, basal FSH level, and BMI (p=0.209, p=0.959, p=0.866 and p=0.685, respectively) . The success rates of clinical pregnancy did not strongly correlate with endometrial thickness. The study found that EMT is not a valid indicator for clinical pregnancy in frozen-thawed embryo transfer cycles.
The Effect Of Plyometric Training On Improving Smash Ability In Volleyball Athletes: Meta-Analysis Study
Authors: Anggraini Della Berliana Aprilia , Hariadi Imam , Hanief Yulingga Nanda
Published: October 2023

This study aims to determine the effect of several plyometric exercises on improving smash skills in volleyball. Many studies have conducted this research in the field of sports. Various kinds of studies explain that plyometric training has a very positive effect on improving volleyball smash abilities, but the results of the data presented tend to be different, with this it is necessary to re-analyze the data in order to provide comprehensive information about plyometric training on improving volleyball smash abilities. The meta-analysis method used in this study was assisted by Jeffreys's Amazing Statistics Program (JSAP) software version 0.16.0.0 by collecting data from research results that already exist in databases such as Google Scholar. Literature search from Google Scholar using the keywords: “plyometric” OR “plyometric” AND “smash” with a range of 2010-2022. The sampling technique used in the search for articles is fulltext articles and article research is carried out in Indonesia. The results of the search with these keywords found a population of 979 articles and 11 samples used, then this data will be retrieved according to the inclusion and exclusion that have been determined. The results of this study indicate that the RE model was identified as 1.15 from the results of studies that have been analyzed and there is no publication bias, therefore it can be concluded that plyometric training has a high effect on volleyball smash ability.
Duração dos estágios do desenvolvimento pós-embrionário de Porcellana sayana leach, 1820 (Anomura: Porcellanidae) em laboratório
Authors: Morsoleto Felipe Misael da Silva , Werneck Pedro Rondon , Macedo Humberto Rodrigues , Faria Ana Elisa Campos , Da Silva Antônio Francisco Campanha , Monteiro Isabel Boaventura , Brisqueleal Jean Carlos Pianta , Junior Olavo Jose Luiz , Klein Wagner Lopes , Ribeiro Karlos , Betioli Júlio Valentin
Published: October 2023

Os porcelanídeos são Decapoda marinhos da Infraordem Anomura que apresentam grande importância económica e ecológica. Nos ecossistemas como elo entre a matéria orgânica particulada e os níveis tróficos superiores. Porcellana sayana é um, Porcellanidae com distribuição tropical e temperada, pertence a macro e megafauna bêntica associada da pesca dirigida ao camarão e aos bancos da vieira. Os representantes da Infraordem Anomura tem como característica possuir estágio larval constituído de pré-zoeia, duas fases de zoeia e megalopa. A proposta desse estudo foi estabelecer o tempo de vida de cada uma das fases de desenvolvimento de P. sayana, mantidas em condições de laboratório. As larvas foram obtidas de fêmeas ovígeras coletadas na região de Ubatuba – SP e mantidas em sala climatizada no laboratório do Departamento de Zoologia do Instituto de Biociências, UNESP Campus de Rio Claro. A temperatura foi mantida em 24 +/- 1 oC, a salinidade de 34 o/oo, sob fotoperíodo natural. Após a a eclosão 63 larvas foram transferidas individualmente, para placas de Petri de 20 ml com de água do mar previamente filtrada e aerada; receberam como alimento cerca de 40 náuplios recem-eclodidos. Diariamente foram constatadas a mortalidade e verificação da ocorrência de exúvias, com a consequente mudança de estágio. O tempo de duração de cada estágio larval foi anotado e analisado. Constatou-se que a duração média (em dias) para os estágios larvais de zoeia I foi de 5,9; zoeia II 9,9 e megalopa 10,7. A estratégia reprodutiva adotada por P. sayana condiz com o tamanho do ovo, redução dos estágios larvais e menor taxa de predação quando o organismo se encontra mas fases imaturas e como componente do plâncton. Estas pesquisas contribuem para o maior conhecimento sobre o ciclo de vida das espécies; para estudos de biologia pesqueira, juntamente com os dados de captura e biologia dos adultos e em estudos ecológicos e de manejo.
Big data em organizações de médio e grande porte do setor público brasileiro
Authors: Schaulet Evandro , Trez Guilherme
Published: October 2023

Este estudo é a replicação da pesquisa de Klievink et al. (2017) aplicada no governo holandês, utilizando as dimensões de alinhamento para tecnologia da informação, capac-idades e maturidade organizacional. A questão de pesquisa é: em que medida as organi-zações do setor público brasileiro estão prontas e preparadas para utilização de iniciativas de big data? Foi realizada uma pesquisa quantitativa com 101 representantes de organi-zações públicas. O resultado mostrou que os órgãos públicos brasileiros não estão pron-tos para a implementação de big data. As conclusões mostram que é necessário fomentar atividades na coleta de dados, compartilhando informações entre organizações e uma mudança de pensamento dos gestores públicos sobre a importância das informações na tomada de decisão.
Efeitos da dieta livre de glúten nas doenças do sistema nervoso em pacientes portadores de Doença Celíaca: uma revisão sistemática
Authors: Marques Maria Nádia da Nóbrega , Bezerra André Luiz Dantas , Macedo Marriane Brito , De Pontes Filho Rui Nóbrega , Mazzaro Vandezita Dantas de Medeiros , De Medeiros Nara Maria Holanda , Toledo Miguel Aguila , De Sousa Milena Nunes Alves
Published: October 2023

Introdução: A doença celíaca é uma patologia multifatorial, que se desenvolve a partir da exposição, de indivíduos predispostos geneticamente, à proteína do glúten. Suas manifestações clínicas dependem da forma como a doença se apresenta, forma clássica, não clássica ou assintomática. O tratamento é fundamentado em uma dieta livre de glúten (DLG). Assim, objetivou-se identificar os efeitos da DLG nesses pacientes. Metodologia: Revisão sistemática da literatura realizada em bases de dados nacionais e internacionais. Foram incluídos ensaios clínicos que avaliassem os efeitos da DLG nos sintomas neurológicos da doença celíaca. Resultados: Foram selecionados 06 estudos, com um total de 692 pacientes, avaliando-se os efeitos da DLG nesses indivíduos. Quatro dos seis estudos analisados apresentaram uma boa resposta a essa dieta, possivelmente devido a uma reorganização funcional proporcionada por ela. Conclusão: Não foi possível atestar a eficácia da DLG devido a não elucidação dos mecanismos fisiopatológicos das doenças neurológicas em pacientes portadores de doença celíaca.
Uso de ozonioterapia em pacientes ateroscleróticos: uma revisão integrativa
Authors: De Sousa Milena Nunes Alves , Lopes Fernando Lima , Toledo Maribel Caridad Aguila , De Medeiros Nara Maria Holanda , Toledo Miguel Aguila , Macedo Marriane Brito , Mazzaro Vandezita Dantas de Medeiros , Dias Thuany Rodrigues , Da Nobriga Eliane Raimunda , Bezerra André Luiz Dantas
Published: October 2023

Objetivo: Analisar a influência da ozonioterapia no desfecho sintomático de pacientes arterioscleróticos e o impacto na qualidade de vida dos pacientes. Método: Revisão integrativa, realizada nos bancos de dados U.S. National Institutes of Health's National Library of Medicine (NIH/NLM – PUBMED), Biblioteca Virtual em Saúde e Cochrane Library. Após avaliação criteriosa foram selecionados 13 artigos para a realização do estudo. Resultados: Constatou-se que a maioria dos estudos atestaram a eficácia (92%; n=12) da ozonioterapia no desfecho e qualidade de vida de pacientes com doenças arterioscleróticas. Mesmo com os achados expressivos, incluindo redução da taxa absoluta de amputações em 20%, o número de estudos relacionados ao objeto de estudo é limitado, inversamente proporcional à gravidade das doenças ateroscleróticas e aos resultados significativamente positivos obtidos pela quase totalidade dos estudos selecionados. Conclusão: Conforme os dados apresentados nos ensaios clínicos, notou-se que a ozonioterapia apresentou resultados positivos e significativos em pacientes com diversos níveis de aterosclerose; não foi demonstrado um método de excelência para aplicação de ozônio nos pacientes.
A educação de jovens e adultos no Brasil Pós-LDB/96: há possibilidades emancipatórias?
Authors: De Freitas Eduardo Silva , Vermelho Sônia Cristina Soares Dias
Published: October 2023

As reflexões feitas neste trabalho são parte de um trabalho de pesquisa de doutorado, onde foi importante conhecer e discutir os caminhos que a educação de jovens e adultos (Eja) veio percorrendo ao longo do tempo. Dessa história, sintetizamos a base para discutir melhor a contemporaneidade da Eja e suas potencialidades, visando o objetivo de analisar suas possibilidades emancipatórias dentro de um contexto político burguês e cada vez mais dominado pelas relações capitalistas de mercado. O que se pensa sobre a Eja hoje pode fazer dela um instrumento de transformação social? Nossa reflexão diz que há muito que avançar nas discussões sobre a Eja, a fim de que ela possa contribuir de fato para as transformações sociais efetivas, e não somente para as individuais. Ainda assim, a Eja deve ser fortalecida e politizada, no sentido dado por Freire, onde toda educação é política.
Photovoltaic energy production systems and the carbon market in Maranhao: a case study
Authors: Leitão Beatriz Martins , Silva Fabricio Brito , De Miranda Rita de Cassia Mendonca
Published: October 2023

The dissertation deals with a research carried out with data from a 168.4kWcc/120kWca photovoltaic solar plant installed in Itapecuru Mirim, in the state of Maranhão, with the objective of modeling a system for parameterization and possible calculation of the effect of the solar photovoltaic system on the market of carbon credit. Throughout the introduction and the theoretical framework, advances in photovoltaic solar technology in the world and in Brazil are presented. The project aims to carry out data collection such as power, voltage, current, yield and performance in a solar farm already obtained in the system and analyze the impact of the efficient use of solar energy. The system used as a base has the following characteristics: plant for distributed generation, in remote self-consumption mode, use of Canadian modules, kUmax line, CS3U-380|385|390|395|400MS, 1000V/1500V, number of boards: 440 units, 22 units of strings of 20 modules. and 2 units of Sungrow SG 60KTL inverters, total area: 0.31h, rated power: 1.36kWp, inverter power: 120Kw. The methodology consists of the following steps: First, discussing the role of the solar photovoltaic system in carbon crediting models, starting with a discussion of this type of system in the global scenario, the role in the global and regional scenario. Then, the impact of solar photovoltaic projects on the avoidance of atmospheric carbon emissions will be evaluated, and based on data obtained from the photovoltaic solar plant in Itapecuru Mirim - MA, a model and visualization of the impact result for the state will be carried out.
Short-term effect of active lower limb cycle ergometry on mobility and muscle strength in critically ill patients: a randomized blinded clinical trial
Authors: De Andrade Nayanne Paula , Nawa Ricardo Kenji , De Carvalho Eliane Maria , Dionísio Valdeci Carlos
Published: October 2023

Background: The effects of in-bed cycling on mobility and muscle strength is not well established, in parts due to the difficulty of measuring mobility. Objective: Investigate the effect of active lower limb cycle ergometry on mobility and muscle strength in critically ill patients evaluated by the Perme Intensive Care Unit Mobility Score and Medical Research Council, respectively. Methods: Critically ill patients dependent on mechanical ventilation were randomized, determining the control group and the experimental group. A intervention was applied for eight consecutive days and a blind physiotherapists assessed mobility before and after interventions. The experimental group (EG) was an active lower limb in-bed cycle ergometry by 15 minutes (once a day), associated with routine physiotherapy intervention (twice a day). The control group (CG) had routine physiotherapy intervention. The two-factor mixed ANOVA with Bonferroni correction tested the mobility status and muscle strength, evaluated by Perme Intensive Care Unit Mobility Score and Medical Research Council, respectively. Results: Thirty-seven patients were eligible, but 24 completed the study (12 each group). There was an interaction between interventions (before and after) and groups for mobility (F=59.513, p=0.006). But there was no interaction for muscle strength (F=4.097 p=0.055). The groups were similar before intervention for mobility [(p=0.343); confidence interval: (CG: 8.239 to 10.761) and (EG: 7.405 to 9.928)], but only the experimental group demonstrated improvement in mobility post-intervention [(p=0.017); confidence interval: (15.807 to 21.193)]. Conclusion: Compared to routine physiotherapy, in-bed cycling improved the mobility level, but not in muscle strength. Perme score was sensible to measure the mobility evolution in critical patients.
Estudio del impacto de la producción de biodiesel para Argentina y Brasil: trade-off por el uso de la tierra y en la disponibilidad de su materia prima
Authors: Sattler Silvana Andrea , Centenaro Moisés , Asis Inés del Valle , Gonzáles Enrique Leopoldo Castro
Published: October 2023

La aparición de los biocombustibles, como aplicación alternativa a la producción agrícola, ha llevado a la competencia por el uso del suelo. Dado el trade-off presente en el uso del suelo por los biocombustibles vs. alimentos, en este trabajo se plantea analizar el impacto de la producción del biodiesel sobre los recursos y la disponibilidad de materias primas y se examinará la industria del biodiesel, sin considerar la del etanol, considerando como base el esquema teórico tomando el trabajo de Msangi et al. (2010), sobre el cual se plantean modificaciones en la aplicación.
Novos espaços de gênero e sexualidade no cinema feito por/sobre mulheres
Authors: MORAES E. L. R.
Published: October 2023

Este trabalho pretende analisar inicialmente a presença crescente de mulheres diretoras na cinematografia brasileira contemporânea – que aqui compreende desde o movimento denominado Cinema da Retomada até os dias de hoje. Focalizando a importância de um cinema feito por/sobre mulheres, uma minoria ainda subalternizada no que compete a poder e legitimidade, se procurará investigar como cada uma delas, ao tomar o lugar de fala e portar-se como o sujeito de suas próprias representações, tende a contribuir para o desmonte do discurso dominante inerente ao homem, e, portanto, fazer dos seus filmes espaços de criação de novos enunciados, feministas ou não, capazes de apreender o discurso habitual sobre o gênero e a sexualidade como um conjunto de proposições repetidas que adquirem a aparência de verdade.
APPROACHES TO THE DESCRIPTION OF EXCEPTIVE AND
ADDITIVE CONSTRUCTIONS IN RUSSIAN STUDIES
Authors: Yakovchenko Anastasia A.
Published: October 2023

This article presents a review of papers describing exceptive (e.g. All
my classmates came to the birthday party, except for Ivan) and additive (e.g. Besides Ivan, all my classmates came to the birthday party) constructions. The main aims of
this work are to compare different points of view, as well as identify some features
of functioning of these constructions in the Russian language that were not mentioned
before. Section 1 discusses the markers of addition or exclusion. Section 2 is devoted to the constituents of the constructions. Section 3 deals with the issue of
monosemy and polysemy of krome ‘except; besides’, as well as examples of ambiguous interpretation of krome. Section 4 raises the question what part of speech krome
belongs to and the possibility to include krome into the functional class of connectors.
THE ORIGINS OF THE EARLY CLOSURE BAN
IN THE RUSSIAN LITERARY STANDARD
Authors: Alekseev Danil A. , Fedorova Olga V.
Published: October 2023

: The Early and Late Closure phenomenon has been present in the psycholinguistic spotlight since the 1970s. Decades of research on the topic have shown
not only that resolving attachment ambiguity is influenced by such factors as the
length of the relative clause and speaker’s working-memory capacity, but that speakers of different languages tend to prefer either Early or Late Closure. Investigations
of attachment ambiguity in Russian have come to the conclusion that Russian is a
language with a preference towards Early Closure. However, during the trials some
speakers of Russian claim that high attachment is ungrammatical and justify their
view by some kind of grammatical rule they have been taught in school. The origins
of this supposed rule have so far been unknown. The article at hand shows that the
Early Closure Ban in literary Russian has its roots in works on Russian grammar
that date back to the early 19th century. This rule evolved from a simple generalization of the linear position of relative clauses to an outright ban which came to life
with the advent of Soviet mass media. Such stylistic guidelines in other literary
standards are theorized to be factors which need to be accounted for when conducting research on attachment ambiguity in languages of the world.
“THE INTERNAL FORM OF THE VERSE” AND THE INNER
WORD: OSIP MANDELSTAM’S CONVERSATION ABOUT
DANTE IN THE PSYCHOLINGUISTIC PERSPECTIVE
Authors: Kikhney L.G. , Temirshina O.R.
Published: October 2023

The object of the study is Mandelstam’s article Conversation about
Dante, considered in a psycholinguistic perspective.
The article puts forward a hypothesis that the problem of the genesis of a poetic
text in Mandelstam’s metapoetics has its ontological justification in the idea of inner
word. Such a connection can be explained by the fact that the literary text is considered by Mandelstam in its genetic dimension — from the standpoint of the generation of literary speech.
Mandelstam’s focus on the genetic aspect of the birth of a word leads to regular
intersections of the poet’s searches with the psychological concepts of inner speech.
So, firstly, the inner image of the verse, which, according to Mandelstam, stands
at the beginning of the poetic text, is typologically related to the inner word. Both
phenomena are correlated with pre-text / pre-speech stage, have a double representation as image and the word, and are primarily manifested in the articulatorysyntactic code.
Secondly, the principles of unfolding turn out to be common to the inner word
and the artistic word, taken in its genetic aspect. Just as the “clot of personal meanings” (Vygotsky) in its deployment moves from the primary ‘synsemantic’ stage to
verbal differentiation, so the “compositional clot” (Mandelstam), initially arising as
a single semantic impulse, unfolds in the level space of the language.
Thirdly, both the inner word and the artistic integrity postulated by Mandelstam
exist in a special spatial modus, which is characterized by semantic simultaneity and the absolute dominance of semantics over syntax. Fourthly, the finished speech
product is understood by Mandelstam both as a result and as a process, which, on
the one hand, leads to the aesthetics of a draft, and on the other hand, matches
Mandelstam’s ideas with the concepts of inner speech, where the remnants of the
primary semantic syntax are found.
Humán papillomavírus elleni védőoltás bevezetése Magyarországon: az oltási stratégia alakulása 2014-től napjainkig
Authors: Molnár Zsuzsanna
Published: October 2023

A méhnyakrák világszerte népegészségügyi probléma, annak ellenére, hogy hatékony eszközeink vannak a betegség megelőzésére: az egyre fejlettebb szűrési módszerek kifejlesztése, valamint a mérföldkövet jelentő HPV oltóanyagok törzskönyvezése, bevezetése és a Nemzeti Immunizációs Programokba (NIP) történő beépítése. Hazánkban a szélesebb körű HPV elleni immunizáció az önkormányzati kampányoltásokkal indult, a védőoltás 2014-től lett a NIP része. Ma már a 9 valens HPV oltóanyaggal kaphatják meg az önkéntes, térítésmentes védőoltást iskolai kampányoltás keretében a 12. életévüket betöltött és az általános iskola 7. évfolyamát végző leányok és fiúk. Az utóbbi két évben az igénybevételi arány nemzetközi összehasonlításban is kiemelkedő, lányoknál 80% körüli, fiúk esetében pedig 66% és 71% volt, amely egyelőre még elmarad a lányokétól. Az Egészségügyi Világszervezet (World Health Organization, WHO) 2020-ban elindított méhnyakrák-elimináció felgyorsítását célzó globális stratégiája a HPV elleni átoltottság tekintetében célul tűzte ki, hogy 2030-ig el kell érni, majd fenntartani, hogy a lányok 90%-a 15 éves koráig legyen beoltva HPV ellen. Ehhez évről évre tájékoztatni kell az érintett szülőket arról, hogy a HPV elleni védőoltás biztonságos és hatásos védelmet nyújt gyermekük számára a humán papillomavírussal összefüggő megbetegedésekkel szemben, ezzel hosszú távon szolgálva gyermekük egészségét.
BERLÍN NO SELLADO
Authors: STEININGER FLORENTIN , KRIJNEN SJOERD
Published: October 2023

Estimulados por la iniciativa del refere?ndum acerca de un Berli?n sin automo?viles, en este arti?culo exploramos el significado del cambio sistema?tico en el metabolismo de la ciudad, al dar un nuevo uso al espacio comu?n. Reunimos nuestras propias experiencias, aludimos al espi?ritu poli?tico y cultural de Berli?n, analizamos las transformaciones histo?ricas, ya sean uto?picas o disto?picas y, como en la secuencia inicial, queremos especular sobre las posibilidades que se abren al redefinir, de manera dra?stica, el espacio pu?blico de Berli?n como un ha?bitat urbano-natural.
El aprendizaje basado en problemas para el aprendizaje de la macroeconomía 2018
Authors: Diez Matallana Ramón
Published: October 2023

Con el objetivo de probar la hipótesis de que el ABP era mejor estrategia para el aprendizaje de macroeconomía que la enseñanza tradicional en la UNALM, se empleó el método hipotético-deductivo con un diseño no experimental, correlacional de corte transversal; se recogió la información en el segundo ciclo del año 2018, con una encuesta no probabilística y un cuestionario como instrumento de colecta de datos. La confiabilidad del instrumento se verificó con el Alfa de Cronbach que resultó: 0,927 para la comprensión de conceptos macroeconómicos y 0,93 para la redacción en macroeconomía. Para el análisis descriptivo se realizaron tablas de distribución de frecuencias y gráficos de barras. La prueba de hipótesis se ejecutó con la prueba U de Mann Whitney. Se concluyó que, la estrategia de aprendizaje basado en problemas y la variable comprensión muestran un Z = -3,527, mientras que la estrategia de aprendizaje basado en problemas y la redacción muestran un Z=-3,071. Dado que P valor < 0,05; hay significancia en la correlación, confirmando la hipótesis y cumpliendo el objetivo. Se recomienda estudiar esta estrategia en otros cursos de Economía.
Virtual Tour Method as an Alternative Tourism Experience During The Covid-19 Pandemic (Case Study of Villages Nglanggeran, Yogyakarta)
Authors: Nuryadina Augusrini  , Yanti Suzana  , Novi Handayani  , Rhamadeta Thasya Putri
Published: October 2023

Purpose: The aim of this research is to take a consumer perception and to find out the interest of consumer about virtual tour and wants to get the impact tourists feel regarding the virtual tour in Nglanggeran Village
Research method: This research uses qualitative research through observation, interview, and survey. The author makes observations by participating in virtual tours online and conducting interviews with virtual tour participants to obtain data.
Results and discussion: There are three big results obtained that the virtual tour still had much homework to fix and reach because of several factors that obstructed it. The first factor: the virtual tour cannot make visitors feeling enjoy the tour. The second factor: visitors cannot be satisfied with the tour by virtual because there is not interaction directly with nature. The third factor: another visitors are not enjoy the virtual tour because it’s not real. That means virtual tour must be fixed from the internet connection, guide, time duration, facilities, and infrastructure that can make tourists feel the actual travel experience like  real and live.
Implication: Virtual tours are indeed inviting tourists to carry out tourism activities during a pandemic. However, several factors can minimize the tourist experience in virtual tours. This means that Virtual tours can be used as an alternative for traveling during a pandemic, but the inhibiting factors must be seen so that they can be maximized.
 
Keywords: COVID-19, Virtual Tour, Nglanggeran Tourism Village, Tourist Interest, Travel Experience
Implementation of Sustainable Tourism at Ketapang Beach Lampung
Authors: Ni Made Ayu Windu Kartika  , I Gede Mudana
Published: October 2023

Purpose: This study aims to analyze the implementation of sustainable tourism in the operation of Ketapang Beach (Pantai Ketapang) in Lampung, Sumatra.
Research methods: It is a descriptive, qualitative research. The data was collected by direct observation, document study, and literature studies from related journals.
Results and discussion: Ketapang Beach requires development that involves all tourism stakeholders because it has much potential to be developed but has not been planned and realized correctly.
Implication: This study explains the potential possessed by Ketapang Beach through a SWOT analysis and provides a sustainable tourism model design for the tourist attraction of Ketapang Beach.
 
Keywords: beach, sustainable tourism, model.
Improvement in Growth in Adolescents with Average Height Using A Massage Chair: A Prospective Single Arm Pre-Post and National Standard Data Comparison Study
Authors: Park Sul Gi , Chang Gyu Tae , Lee Jin Yong , Lee Sun Haeng
Published: October 2023

Background: This study aimed to examine the changes in height, weight, and bone age between pre- and post-intervention when using a BEG-100 massage chair daily.Methods: Thirty-five children aged 11 years who were close to the average height (145-155 cm) were included in the study. There were 34 participants who used the BEG-100 massage chair for 24 weeks. Daily intervention consisted of 20 minutes of lower body massage and 10 minutes of whole-body massage. Height, weight, and adverse events were checked every five visits, while a hand X-ray was used before and after massages. The height percentile and height standard deviation score (SDS) were calculated using the 2017 Korean growth chart. The bone age and predicted adult height using radiographs were computed using the Tanner-Whitehouse method. The paired t-test or Wilcoxon signed-rank test was used according to normality of data to determine statistical significance.Results: A total of 31 children were included in the final analysis. The height percentile and height SDS significantly increased after BEG-100 massage chair use (2.39; p = 0.032, and 0.07; p = 0.036, respectively). However, these changes were not significant in children whose baseline height was shorter than the average. There were no significant differences in bone age, height for bone age, predicted adult height, or sitting height/height ratio. None of the participants complained of adverse events.Conclusion: The height percentile and SDS of teenagers increased after use of massage chair therefore, it is necessary to perform larger randomized controlled clinical studies. Trial registration: KCT0004673.
Structural and Criterion Validity of a New 6-item Roland–Morris Disability Questionnaire (RMDQ-6) on Patients with Chronic Lower Back Pain Receiving Integrative Medicine
Authors: Lee Yoon Jae , Shim Gyu Chan , Yang Changsop , Han Chang-Hyun
Published: October 2023

Background: Lower back pain (LBP) is a leading cause of disability worldwide. The Roland–Morris Disability Questionnaire (RMDQ) has been widely used to assess functional impairment in patients with LBP. However, its length and redundancy calls for a more concise and optimized version.Methods: We conducted a secondary analysis of data from two randomized controlled trials comparing pharmacopuncture and physical therapy for chronic LBP. We focused on 132 patients with moderate-to-severe symptoms and analyzed their baseline data to evaluate the structural validity of the RMDQ. We used R packages lavaan and semPlot for confirmatory factor analysis (CFA). Model fit were assessed through various indices, including comparative fit index, Tucker–Lewis index, root mean square error of approximation, and standardized root mean squared residual.Results: A total of 18 items were ultimately removed to produce a streamlined 6-item structure. Our model met the fit index criteria, yielding a one-domain, 6-item RMDQ structure. While the relative indices fell slightly short of the ideal values, the RMDQ-6 derived through CFA correlated well with the original version.Conclusion: This study developed a more concise version of RMDQ through CFA to optimize its structural configuration. This concise instrument can be proposed as an efficient tool to assess the functionality of patients with LBP.
SOSIALISASI BAHAYA BORAKS DAN FORMALIN PADA MAKANAN DI SMPN 3 TEBAS
Authors: Pratama Gusti Randy , Kristiandi Kiki , Alfaisyal Ruwendi , Pratiwi Nurul , Puspa Puspa , Sabrina Era , Indah Indah , Ismiadi Ismiadi
Published: October 2023

Borax and formalin are chemicals that are prohibited by law as food additives. Borax and formalin contain preservatives that are harmful to the body. There are many uses of borax and formalin in processed food circulating in the community so students must be more careful in choosing healthy foods. This socialization aims to increase students’ knowledge about the dangers of borax and formaldehyde and to be more careful in choosing food. The activity was carried out at Tebas 3 Public Middle School, on Wednesday, June 7, 2023. The socialization method used in this activity focused on communication, information, and education activities. The result of this socialization is that students become more careful in choosing nutritious foods and know the characteristics of foods that contain borax and formalin. Tebas 3 Public Middle School students who are in their teens need a balanced nutritional intake and must consume healthy and nutritious food so that the socialization of the dangers of borax and formalin can increase the knowledge, concern, and understanding of these students
The Implementation of the Merdeka Curriculum (Independent Curriculum) in Strengthening Students’ Character in Indonesia
Authors: Fauzan Fauzan , Ansori Raden Ahmad Muhajir , Dannur Moh. , Pratama Angga , Hairit Artamain
Published: October 2023

The implementation of the Merdeka Curriculum in Indonesia is a fresh innovation in the educational system, from the teaching methods to the learning results. The goal of the autonomous curriculum is to develop kids' character by giving them opportunity to study informally, quietly, joyfully, and while paying attention to their inherent abilities. The Merdeka Curriculum gives students the ability to autonomously plan and create learning strategies that suit their needs and environment. The Pancasila students’ profile, which includes faithful, devoted to god almighty, and, noble, globally diverse, mutual cooperation, independent, critical reasoning, and creativity, is used in this project-based curriculum to develop soft skills and character while focusing on key concepts and being implemented flexibly. In order to produce superior human resources and character developed in accordance with existing characteristics with various activities and stages that ultimately result in students with character and collaboration, it is anticipated that this curriculum will strengthen learning outcomes, strengthen character, and collaborate with various parties both nationally and internationally.
Perancangan Sistem Informasi Inventory Barang Berbasis Web Pada PT Makro Rekat Sekawan
Authors: Aditya Vichy , Sundari Jenie
Published: October 2023

Inventory merupakan kumpulan barang yang umumnya disimpan di berbagai lokasi seperti gudang tertutup, area lapangan, gudang terbuka, atau tempat penyimpanan lainnya. Barang-barang tersebut dapat berupa bahan baku, barang jadi, komponen operasional, atau barang yang digunakan dalam suatu proyek.PT Makro Rekat Sekawan adalah perusahaan yang bergerak di bidang Glue Stick, Hotmelt PSA, EVA HOTMELT, Hotmelt Sintetis, Polyurethanes dan Lem Water Based. Selain memproduksi terdapat juga penjualan dari hasil produksi itu sendiri dan daftar produknya terus bertambah seiring dengan berkembangnya industri di Indonesia. Tetapi untuk pengolahanya masih menggunakan sistem manual, sehingga sering terjadi kesalah retur data ataupun kehilangan data tersebut. Dan pada akhirnya laporan data barang masuk dan keluar kurang akurat.Akhirnya merancang sebuah sistem aplikasi berbasis web yang berperan sebagai saran atau alamat bantu untuk memudahkan karyawan dalam melakukan inventory barang di PT Makro Rekat Sekawan.Dengan penerapan sistem informasi untuk mencatat barang masuk dan barang keluar, proses pengolahan data tersebut menjadi lebih efisien dan efektif. Selain itu, laporan yang dihasilkan lebih cepat dan akurat, menghemat waktu yang diperlukan dalam proses tersebut.
Analisis Kesiapan Guru dalam Menerapkan Media Pembelajaran Kurikulum Merdeka di SMPN 28 Surabaya
Authors: Hidayah Fitri , Diantari Shevia Dwi , Prasietyawan Ruben Diaz
Published: October 2023

Curriculum changes in Indonesia, especially the independent learning curriculum, emphasize the independence of students and the readiness of teachers in learning. The purpose of this study is to analyze the readiness of teachers at SMPN 28 Surabaya in implementing the independent curriculum teaching media. The type of research used is a qualitative approach by conducting interviews with the deputy head of the curriculum as a respondent. The data collection technique used is descriptive analytics resulting from interviews. The results show that teachers' understanding has reached an adequate level, some things need improvement, especially in providing further training to teachers who need to improve their response to curriculum changes. The role of the students involved in designing teaching media, the use of technology which is one of the helpers in using teaching media, and the obstacles encountered when designing teaching media for this independent curriculum.  This conclusion is based on the empirical findings contained in the main text of this study, providing a comprehensive picture of the readiness to adopt the independent curriculum at SMPN 28 Surabaya.
Implementasi Model Pembelajaran TGT dan Media Quizizz untuk Meningkatkan Hasil Belajar Matematika pada Siswa Kelas 3 di SDN 23 Ampenan
Authors: Yunita Reta , Rokhmat Joni , Triapuri A. Hegar
Published: October 2023

This research is entitled: "Implementation of the TGT Learning Model and Quizizz Media to Improve Mathematics Learning Outcomes for Grade 3 Students at SDN 23 Ampenan". The aim of this research is to improve learning outcomes in mathematics lessons regarding angles through the Teams Games Tournaments type learning model for students in Class III SDN 23 Ampenan. The method used in this research is Action Research which consists of 2 (two) cycles, and each cycle consists of: Planning, Implementation, Observation and reflection. Based on the results of action research, the Teams Games Tournaments Type Learning Model can improve the Mathematics Learning Outcomes of Class III students at SDN 23 Ampenan. Furthermore, the researcher recommends: (1) Teachers who experience the same difficulties can apply the Teams Games Tournaments Type Learning Model to improve the Mathematics Learning Outcomes of Class III students. (2) In order to get maximum results, teachers are expected to better understand the Teams Games Tournaments Learning Model.