bluuebunny/crossref_metadata_2025 huggingface dataset:
Lesión pulmonar aguda post transfusional: reporte de caso y revisión de bibliografía
Authors: Granados Alvarado Laura , Rojas Chávez Alejandro , Rojas Sáurez Rafael
Published: January 2019

Se reporta caso de una paciente femenina de 59 años quien ingresó al Servicio de Cirugía Plástica del Hospital San Juan de Dios, por historia de quemadura de tercer grado que afectó el 25% del área corporal total, quien a las 48 horas post transfusión de glóbulos rojos empacados presentó cuadro de disnea asociado a hipotensión que requirió uso de ventilación mecánica y vasopresores. Posterior a un realizar un diagnóstico diferencial exhaustivo, se cataloga como lesión pulmonar aguda post transfusional (TRALI)
Intervenciones de enfermería en pacientes con diabetes mellitus tipo 2 que aumentan sus conductas de autocuidado: revisión integrativa
Authors: Aguayo-Verdugo Natalia Valeska , Orellana-Yañez Alda Ester
Published: January 2019

RESUMEN

El objetivo de esta revisión fue identificar intervenciones de Enfermería que aumenten las conductas de autocuidado en pacientes con diagnóstico de Diabetes mellitus tipo 2. Es una revisión integrativa donde se realizó una búsqueda en las bases de datos en SciELO, BVS, PUBMED y WOS, entre septiembre y diciembre del 2017, utilizando los descriptores; diabetes mellitus tipo 2 AND autocuidado AND atención de Enfermería, en idioma español, inglés y portugués. Inicialmente se identificaron 2.534 publicaciones y tras la aplicación de; filtros, criterios de selección y escala JADAD, la muestra seleccionada fue de 10 artículos. En cinco de los estudios la intervención tuvo resultados positivos con respecto al autocuidado, de las cuales cuatro utilizaban estrategias derivadas de la psicología como; entrevista motivacional, teoría del cambio de comportamiento y resolución de problemas. Se concluye que los profesionales de Enfermería deben profundizar en el área de la psicología y formar equipos de trabajo con estos profesionales, ya que las personas con diabetes mellitus tipo 2 necesitan un cambio de comportamiento a largo plazo. Por lo tanto, también se necesitan intervenciones de larga duración para lograr estos cambios y aumentar la calidad de vida de estos pacientes.
Subjective palatability and appetite after gluten-free pasta: A pilot study
Authors: Cioffi I. , Santarpia L. , Vaccaro A. , Naccarato M. , Iacone R. , Marra M. , Contaldo F. , Pasanisi F.
Published: January 2019

The interest in gluten-free (GF) diet has greatly increased also in people without celiac disease (CD). This pilot study aimed to investigate the postprandial effect of GF-pasta, made by using the pasta-making process applied to artisan wheat pasta, on palatability, appetite sensation, and glucose metabolism in 8 healthy volunteers. Two iso-caloric lunch-meals consisting of: 1) gluten-free pasta (GFP) and 2) refined wheat pasta (RP) were compared in cross-over design. Both subjective appetite, assessed by visual analogue scale (VAS), and blood sample were taken before meal and at half-hour intervals for 4 hours. Palatability was evaluated immediately after the meal-test by VAS. All participants underwent pre- and postprandial energy expenditure (EE) measured by indirect calorimetry. We found that subjective palatability did not significantly differ between meals. Similarly, repeated measures ANOVA showed that GFP did not affect appetite ratings, postprandial glucose, and insulin responses compared to RP. Then, postprandial EE was affected by time (P=0.006), increasing at 60 min, but not by meals. In conclusion, artisanal GFP was as palatable as RP pasta, without affecting perceived satiety and postprandial glycaemia compared to RP in healthy subjects. Clearly, GFP results are preliminary and need to be investigated in larger studies.
METHODS OF REGULATING PHYSICAL PROPERTIES OF DOUGH USING PHYTOEXTRACTS
Authors: Lebedenko T. , Korkach H. , Kozhevnikova V. , Novichkova T.
Published: January 2019

This paper considers the prospects of using phytomaterials to solve the problems of baking industry, caused by the instability and defects of wheat flour, and analyses the main methods of regulating structural and mechanical properties of wheat dough and improving the quality of products made from weak flour. The prospects of using phytomaterials as natural alternatives to synthetic additives and baking improvers are presented. The chemical composition and the content of active substances in rosehips (the dogrose fruit) and hawthorn fruit are analyzed as to their effect on increasing the nutritional value and improving the protective properties of products as well as their effect on the course of the technological process, the quality of semi-finished and finished products. The methods of processing the phytomaterials have been suggested, and the optimum parameters of their extraction have been determined as to their effect on the protein-proteinase complex. Water and milk whey are suggested as extractants with the 1:10 ratio between the raw materials and the extractant, while the optimal temperature (100°C) and duration (60 minutes) of extraction were determined experimentally. Rational doses of phytoextracts have been found on the basis of their influence on gluten elasticity and the physical properties of wheat dough during its mixing and fermentation (30% of the rosehip water extract, 45% of hawthorn water extract, and 15% of whey extracts to the weight of flour). It has been established that proposed phytoextracts can increase the water absorption capacity of flour with weak and medium-strength gluten during dough mixing, improve its formation, stability, and elasticity, and decrease the degree of dilution according to the study of rheological properties of the dough using farinograph and extensograph. The mechanism of interactions and conformational changes in the structure of gluten proteins with the active substances of phytoextracts, especially pectins, polyphenols, and organic acids, has been suggested. It has been proven that fruit phytoextracts can be used as alternatives to synthetic improvers to process weak flour. Their usage allows solving the problems of regulating the properties of the gluten network and obtaining baked products with high physical, chemical, and sensory qualities. The proposed methods are effective and relatively easy to implement, which is important for small bakeries and restaurant establishments.
DEVELOPMENT OF COOKED SMOKED SAUSAGE ON THE BASIS OF MUSKOVY DUCK MEAT
Authors: Pasichnyi V. , Bozhko N. , Tischenko V. , Kotliar Ye.
Published: January 2019

This study considers the development of combined meat products containing, along with meat raw materials, other types of raw materials of animal and vegetable origin. The aim of the research is to substantiate the advantages of combining duck meat of regional origin with other types of raw materials in meat-containing cooked smoked sausages. A model for studying of the feasibility of combining duck meat of regional origin with other raw materials was a recipe for cooked smoked sausage containing meat of the Muscovy duck and also including pork hearts, salted pork side-fat, soybean isolates, pork skin protein, edible albumin “Aprored.” In the model samples of forcemeat for meat-containing cooked smoked sausages, functional and technological properties have been determined according to standard methods. The biological food value of the finished products has been determined as well. The analysis of the results confirms that the combination of Muscovy duck meat and protein-containing secondary raw materials improves the moisture content, water-holding capacity, emulsifying ability, and stability of the emulsion. The study of the microbiological parameters of the sausages developed has indicated that the number of mesophilic aerobic and facultative anaerobic microorganisms (MAFAM) in all the samples studied was within the normal limits. The study of the number of bacteria of the E. coli group has not detected these microorganisms in any of the samples. For the ω-6 and ω-3 family, its high biological value as for the content of essential amino acids and its biological effectiveness as for the fatty acids have been confirmed. It has been proved that duck meat can be combined with traditional types of meat and vegetable raw materials to increase the biological effectiveness of meat-containing cooked smoked sausages. It has been determined that when Muscovy duck meat is combined with non-meat kinds of protein-containing raw material (pork skin protein, soybean isolate) as part of meat-containing cooked smoked sausage, it allows producing nutritious food with high quality characteristics.
Lifelong learning practices and leisure-time exercise habits of academic and community-based physicians
Authors: Babenko Oksana , Ding Mao , Koppula Sudha
Published: January 2019

This article was migrated. The article was marked as recommended. Objective: Physicians are required to be lifelong learners for the provision of quality patient care. At the same time, physician wellbeing is a critical component in the delivery of such care. This study was designed to examine: (1) lifelong learning practices and leisure-time exercise habits of academic and community-based physicians; and (2) associations of leisure-time exercise with work engagement, exhaustion, and professional life satisfaction. Methods: Using an online survey, quantitative data were collected from physicians practicing in Canada. The survey contained validated scales of physician lifelong learning, leisure-time exercise, work engagement, work exhaustion, and professional life satisfaction. Descriptive, chi-square, t-test, and correlational analyses were performed. Results: Physicians (n=57) reported moderately high levels of lifelong learning, with no significant difference between academic and community-based physicians. To stay current in their practice, the majority of physicians reported exchanging ideas/asking colleagues and searching databases as questions arise (>90%), followed by engaging in clinical teaching and attending conferences and meetings of professional organizations (>80%). Watching podcasts and webinars was the least preferred lifelong learning activity (<50%). With respect to leisure-time exercise habits, more community-based physicians reported engaging in mild and/or moderate forms of exercising, whereas more academic physicians reported engaging in strenuous exercising in a typical week. Correlational analyses revealed that physicians' leisure-time exercise scores were positively correlated with professional life satisfaction (r = 0.25; p = 0.058) and work engagement (r = 0.29; p = 0.028) and negatively correlated with work exhaustion (r = −0.34; p = 0.01). Conclusions: Irrespective of the practice type, physicians tend to engage in lifelong learning activities that offer in-person interactions with colleagues and trainees. Regular participation in leisure-time exercise appears to enhance physicians' professional wellbeing. As such, these activities and habits should be encouraged, supported, and promoted within institutional culture and health systems in general.
An Exceptional America Exceptionally Divided
Authors: Nickerson Alexandra A
Published: January 2019

In this age of stark polarization of American political opinion, learning to communicate effectively across party lines is more important than ever before. Mugambi Jouet's Exceptional America sheds light on the political, social and cultural factors contributing to both the divide between America and the rest of the Western world and the divide between Americans themselves. However, merely understanding such factors is not enough. Translating these understandings into crucial conversations and using them to question our own beliefs is where the challenge lies. Luckily, there is hope: By thinking critically about political issues and embracing uncomfortable conversations with our adversaries, we can begin bridging this painful divide.
Termite assemblages (Blattaria, Isoptera) in two montane forest (Brejo de Altitude) areas in northeastern Brazil
Authors: Silva Israel Soares da , Vasconcellos Alexandre , Moura Flávia Maria da Silva
Published: January 2019

Abstract: Wet enclaves of montane forests in Caatinga domain, locally known as "Brejos de Altitude", are associated with plateau at altitudes greater than 500 m a.s.l. and to orographic rainfall. Termite assemblage structures were studied in two areas of montane forest (Brejo de Altitude) located in the municipalities of Bezerros and São Vicente Ferrer, Pernambuco State, Brazil. Sampling was performed in 65 x 2 m transects, totaling 300 m2/per area; the densities of nests in each area were estimated using six 1300 m2 plots. A total of 35 morphospecies were recorded that belonged to 21 genera and three families, with 133 encounters. The soil-feeders feeding group predominated, followed by wood-feeders species. A total of five species constructing conspicuous nest were recorded in the two areas. The mean density of active conspicuous nests was 2.6 ± 6.3 nests/ha (mean ± sd) in Bezerros, and 21.8 ± 21.4 nests/ha in São Vicente Ferrer. Termite richness in the study areas were within the amplitude ranges recorded in other montane forests. Thus, the results presented here, combined with data from literature, reinforce need additional studies of the termite fauna in montane forest areas, once the "Brejos" are currently under high ecological pressure and their preservation is urgent.
Clinicopathological and Preclinical Findings of NUT Carcinoma: A Multicenter Study
Authors: Jung Minsun , Kim Soyeon , Lee June-Koo , Yoon Sun Och , Park Heae Surng , Hong Soon Won , Park Weon-Seo , Kim Ji Eun , Kim Joon , Keam Bhumsuk , Kim Hyun Jik , Kang Hyoung Jin , Kim Dong-Wan , Jung Kyeong Cheon , Kim Young Tae , Heo Dae Seog , Kim Tae Min , Jeon Yoon Kyung
Published: January 2019

Background

NUT carcinoma is a rare aggressive disease caused by BRD4/3-NUT fusion, and C-MYC upregulation plays a key role in the pathogenesis. Here, we report on the clinicopathological characteristics of Korean patients with NUT carcinoma and the in vitro efficacy of MYC-targeting agents against patient-derived NUT carcinoma cell lines.

Materials and Methods

Thirteen patients with NUT carcinoma were evaluated for p53, C-MYC, epidermal growth factor receptor (EGFR), HER2, and programmed cell death ligand 1 (PD-L1) by immunohistochemistry. The half maximal inhibitory concentration (IC50) values of NUT carcinoma cell lines (SNU-2972-1, SNU-3178S, HCC2429, and Ty-82) were determined using MYC-targeting agents, including bromodomain and extraterminal (BET) inhibitors (I-BET, OTX-015, AZD5153) and histone deacetylase (HDAC) inhibitors (vorinostat, romidepsin, panobinostat, CUDC-907).

Results

Primary tumor sites included head and neck (n = 9) and lung (n = 4). The patient age ranged from 8 to 73 years with the male/female ratio of 1.2:1. Nine patients died at 3–23.6 months (median, 10.6) after diagnosis. Eight patients had been misdiagnosed initially with other diseases. One patient with metastatic NUT carcinoma who received mass excision plus metastasectomy followed by chemoradiotherapy was a long-term survivor (>27 months). Although expressions of C-MYC (8/12, 73%) and p53 (12/12, 100%) were commonly observed, EGFR, HER2, and PD-L1 expressions were observed in 2 of 7 (29%), 2 of 8 (25%), and 1 of 12 (8.3%) patients, respectively. BET and HDAC inhibitors showed variable but limited in vitro efficacy. However, a dual HDAC/PI3K inhibitor, CUDC-907, was most potent against NUT carcinoma cells, with an IC50 of 5.5–9.0 pmol/L. Consistent with these findings, kinome short interfering RNA screening showed a positive hit for PI3KCA in NUT carcinoma cells. Panobinostat (IC50, 0.4–1.3 nmol/L) and a bivalent BET inhibitor, AZD5153 (IC50, 3.7–8.2 nmol/L), also showed remarkable efficacies.

Conclusion

East Asian patients with NUT carcinoma showed dismal survival outcomes like Western patients, and CUDC-907 might be promising in NUT carcinoma treatment.
Pretreatment for anaerobic blackwater treatment: ultrasonication and thermal hydrolysis
Authors: Zhang Lei , Xu Meiqi , Liu Yang
Published: January 2019

Anaerobic digestion of blackwater converts waste to energy. However, due to a low hydrolysis rate, the hydraulic retention time of a digester can be several days. Here, ultrasonication (30 min) and thermal hydrolysis (at 160°C for 30 min and 2 h) were tested as a pretreatment for accelerating the hydrolysis step. Pretreatment of blackwater with ultrasonication (30 min) and thermal hydrolysis (at 160°C for 30 min) increased the ammonia nitrogen (NH4-N) concentration in the blackwater from 1·16 to 1·46 and 1·51 g/l, respectively. Ultrasonication (30 min) enhanced the biological methane potential of blackwater from 0·48 to 0·62. Although thermal hydrolysis at 160°C for 2 h increased the soluble chemical oxygen demand concentration from 3·0 to 3·6 g/l, this process did not improve biological methane potential.
Development and Validation of the Inventory of Depression and Anxiety Symptoms (IDAS)
Authors: Watson David , Kotov Roman , Chmielewski Michael , McDade-Montez Elizabeth A. , Gamez Wakiza , Stuart Scott , Simms Leonard J , O'Hara Michael W
Published: January 2019

We describe a new self-report instrument, the Inventory of Depression and Anxiety Symptoms (IDAS), which was designed to assess specific symptom dimensions related to major depression and related anxiety disorders. We created the IDAS by conducting principal factor analyses in three large samples (college students, psychiatric patients, community adults); we also examined the robustness of its psychometric properties in five additional samples (high school students, college students, young adults, postpartum women, psychiatric patients) that were not involved in the scale development process. The IDAS contains 10 specific symptom scales: Suicidality, Lassitude, Insomnia, Appetite Loss, Appetite Gain, Ill Temper, Well-Being, Panic, Social Anxiety, and Traumatic Intrusions. It also includes two broader scales: General Depression (which contains items overlapping with several other IDAS scales) and Dysphoria (which does not). The scales (a) are internally consistent, (b) capture the target dimensions well, and (c) define a single underlying factor. They show strong short-term stability, and display excellent convergent validity and good discriminant validity in relation to other self-report and interview-based measures of depression and anxiety.
Dissociations of the Night
Authors: Watson David
Published: January 2019

I examined the associations among sleep-related experiences (e.g., hypnagogic hallucinations, nightmares, waking dreams, lucid dreams), dissociation, schizotypy and the Big Five personality traits in two large student samples. Confirmatory factor analyses indicated that (a) dissociation and schizotypy are strongly correlated—yet distinguishable— constructs and (b) the differentiation between them can be enhanced by eliminating detachment/depersonalization items from the dissociation scales. A general measure of sleep experiences was substantially correlated with both schizotypy and dissociation (especially the latter) and more weakly related to the Big Five. In contrast, an index of lucid dreaming was weakly related to all of these other scales. These results suggest that measures of dissociation, schizotypy and sleep-related experiences all define a common domain characterized by unusual cognitions and perceptions.
Canonical Analysis of the Association Between Attention‐ Deficit/Hyperactivity Disorder with Some Psychological Problems Among Students
Authors: Asghari Arezou , Elham Basiri
Published: January 2019

This study aimed to investigate the relationship between ADHD with internet addiction, depression,

anxiety, stress and social phobia. The study was a descriptive‐correlation study. Statistical Population

of the study was females’ students from Kosar university of Bojnord and, among which 327 students

were selected by random sampling method. Participants completed ADHD Self‐report Questionnaire

(ASRS), Internet Addiction Test (IAT), Depression, Anxiety and Stress Scale (Das‐21), and Social

Phobia Inventory (SPIN). Data were analyzed by applying Pearson correlation coefficient and

canonical correlation analysis statistical tests and SPSS version 23. Pearson correlation’s results

showed that ADHD components (attention deficit and hyperactivity/impulsivity) had positive

significant relationships with internet addiction, depression, anxiety, stress and social phobia

(p0.05). ADHD related to many psychological disorders. So it seems to screen students

with the disorder and designing some treatment interventions for these students to decrease negative

consequences are required.
Efforts to transform Heterosigma akashiwo using an Agrobacterium-mediatedapproach v2
Authors: K Nagarajan Vinay , Accerbi Monica , J Green Pamela
Published: January 2019

This protocol was developed for transformation of Heterosigma akashiwo byAgrobacterium tumefaciens.H. akashiwodoes not grow on solid medium, so transformants are grown "in bulk" and should not be considered clonal. We have had limited success with this protocol and mayrequire further optimization.
The Requirement To Increase The Quality of Power Electronics in Warships
Authors: TURHAN Mahmut
Published: January 2019

Today's and future
ship electrical systems are very different from ship electrical systems in the
past. Power electronics, which are found in systems such as propulsion systems,
power distribution systems, auxiliary systems, weapon systems, sonar and radar
systems, is the most fundamental difference in ship design. The technical specs
also vary in parallel with the development of materials used in power
electronic elements. Graphics, which vary with respect to volume, yield and
temperature, increases more and more in a positive manner. But, what we cannot
see in the positive sense of increase in the power electronics technology is
the inaccuracies that arise from experience. These faults are usually due to
design faults, the interference caused by the switching elements such as IGBT,
tristar and triac used in power electronics, current harmonics, voltage
harmonics, malfunction of sensitive devices due to AC and DC leakage in the
ship's body. To prevent this, it is necessary to develop systems using power
electronic elements which will not interfere with the operation of the system
but may prevent them from occurring
FEATURES OF THE OTTOMAN WAQF ON NORTH BLACK SEA REGION IN THE XVITH CENTURY
Authors: Makarevych A.
Published: January 2019

In the present article the features of the functioning of the Ottoman Waqf in the territory of the North Black Sea region are investigated. It is indicated on the specifics of the city development by the Ottomans, which reflected the achievements of the Islamic-Ottoman civilization. It was determined that one of the important phenomena that had been brought by the Ottomans to this territory was Waqf. The main economic, social and cultural reasons for the occurrence of vaqf in the specified region are indicated. The influence of the waqf on the life of the northern Black Sea coast is analyzed. The main centers of evolution of waqf on the basis of written sources and results of archaeological excavations are considered. Particular attention is paid to the problem, that waqf became an element of the "soft" policy of Islamization and colonization of this territory.
Análisis termodinámico de un disco de freno automotriz con pilares de ventilación tipo NACA 66-209
Authors: García-León Ricardo Andrés , Echavez Díaz Robert Dajjan , Flórez Solano Eder
Published: January 2019

Introducción: El sistema de frenado de un automóvil debe trabajar en forma segura y predecible en cualquier circunstancia, lo cual implica disponer de un nivel estable de fricción, en cualquier condición de temperatura, humedad y salinidad del medio ambiente. Para un correcto diseño y operación de los discos de freno, es necesario considerar diferentes aspectos, tales como la geometría, el tipo de material, la resistencia mecánica, la temperatura máxima, la deformación térmica, la resistencia al agrietamiento, entre otros.

Objetivo: En el presente trabajo se realizó el análisis del sistema de freno a partir del pedal como inicio de los cálculos de cinética y dinámica de los elementos constitutivos y de esta manera simular el comportamiento de un freno automotriz con pilares de ventilación tipo NACA 66-209.

Metodología: El desarrollo de la investigación se llevó a cabo mediante la ejecución de un Análisis de Elementos Finitos (FEA) con la ayuda del Software SolidWorks Simulation, donde se llevó a cabo el modelo geométrico del disco con la finalidad de identificar los elementos sometidos a máximas variaciones de temperatura.

Resultados: Los resultados obtenidos demuestran que con los cálculos matemáticos se logró validar el correcto funcionamiento de sistema de frenado a diferentes condiciones de operación, con lo que se pudo optimizar este tipo de geometría para los discos ayudando a la evacuación más rápida de calor respecto a otros tipos de frenos de disco.

Conclusiones: Los resultados demuestran que estos sistemas trabajan en condiciones óptimas siempre garantizando altos niveles de seguridad y operación en comparación con otros tipos de geometrías, además de poder determinar sus condiciones de funcionamiento en diferentes condiciones de trabajo.
Üniversite İç Paydaşlarının Kurumsal İtibar Algısı: Bolu Abant İzzet Baysal Üniversitesi Kurumsal İtibar Araştırması
Authors: AVCI Kemal
Published: January 2019

Günümüzde organizasyonlar için kurumsal itibar çok önemlidir. Küresel dünyada kıyasıya bir rekabet yaşanmaktadır ve bu rekabet kurumlar için farklı olma gereğini yaratmaktadır. Kurumsal itibar kısaca bir örgütün iç ve dış paydaşlarının örgütle ilgili düşünceleri, varsayımları ve verdikleri değerdir. İtibar, kurumları diğerlerinden farklılaştırır ve itibar iyi yönetilmesi halinde kurumlara çok büyük değer katar. Kurumsal itibar, örgüt yönetiminde ve halkla ilişkiler uygulamalarında da ne tür değişiklik yapıp yapılmayacağı hususunda bir yol göstericidir. Bu çalışmanın amacı iç paydaşlar gözü ile Bolu Abant İzzet Baysal Üniversitesi’nin kurumsal itibarını ele almaktır. Araştırmanın evrenini Bolu Abant İzzet Baysal Üniversitesi’nin iç paydaşları olan akademik ve idari personel oluşturmaktadır. Araştırmada, kolayda örneklemle tespit edilen 376 katılımcıyla ampirik bir saha çalışması yapılmıştır. 5’li Likert tipi ölçekle toplanan veriler SPSS 25.0 paket programında analiz edilmiştir. Faktör analizi sonrasında beş faktör tespit edilmiş ve bulgular yorumlanmıştır. Faktörler açısından sosyo-demografik özellikler arasında bir fark olup olmadığı incelenmiştir. Medya ve tanıtım ile kurumsal kimlik açısından zayıflık tespit edilmiş ve üniversitenin hem bu faktörler için hem de üniversitenin niteliklerini daha iyi yansıtılması açısından stratejik iletişim faaliyetlerinin büyük yarar sağlayacağı tespit edilmiştir
Preoperative serum albumin level as a predictor of surgical complications after emergency abdominal surgery
Authors: V. Sharath Kumar , Prakash Dhruva G. , Pottendla Venkatasiva Krishna
Published: January 2019

Background: Hypoalbumenia has been shown to be associated with increased morbidity and mortality in acute surgical patients due to increased catabolism. This study intends to correlate between hypoalbumenia and postoperative complications in patients undergoing emergency abdominal surgery.Methods: A prospective study is done in a rural tertiary care centre in a total of 190 patients undergoing emergency abdominal surgery after obtaining ethical clearance. In this study preoperative serum albumin and postoperative complications including death up to postoperative day thirty were recorded and gathered using a checklist designed for the study and analysed. Serum albumin less than 3.5g/dl is considered as hypoalbumenia in this study. The correlation between preoperative serum albumin and postoperative morbidity and mortality is assessed.Results: In a total of 190 patients, 93 (48.9%) patients had morbidity and 27 (14.2%) patients had mortality. Preoperative serum albumin less than 3.5g/dl is found in 120 (63.1%) cases and 70 (36.9%) patients has same or more than 3.5g/dl. Patients with preoperative serum albumin less than 3.5g/dl has morbidity in 87 (45.8%) patients than that of normal preoperative serum albumin level which is 6 (3.1%) cases (p= <0.0001, chi-square =72.31). The total mortality is 27 (14.2%) in which all mortality is found in low albumin group compared to no mortality in patients with normal serum albumin. As the albumin level decreases the risk of morbidity and mortality increases with majority of complication in this study occurring in patients with albumin group less than 2.5g/dl to 3g/dl.Conclusions: Preoperative serum albumin is a good predictor of surgical outcome after emergency abdominal surgery.
A comparative study of Centchroman, Tamoxifen and Danazol in management of cyclical mastalgia
Authors: Neogi Probal , Manwatkar Soumitra , Singh Santosh Kumar , Kola Anish , Imran Qazi , Katyayan Ila , Verma Atul
Published: January 2019

Background: Mastalgia is a common problem and 60-70% women encounter it at least once in their lifetime. Many drugs have been used and are been used with varying response, like Tamoxifen, Danazol, primrose oil, topical analgesics and recently Centchroman. The objective of the present study was to compare the three most commonly used drugs in the treatment of mastalgia, namely Centchroman, Tamoxifen and Danazol with a placebo.Methods: All consecutive female patients more than 25 years of age with history of mastalgia for more than 3 months were taken up for the study. Patients were distributed into four groups and administered Centchroman, danazol, tamoxifen and placebo, respectively.Results: In present study of 78 patients, the median visual analogue score (VAS) in Centchroman group were 3, 1 and 3 after treatment of 4, 12 and 24 weeks, respectively with a pre-treatment VAS of 8. Similarly, in the danazol group, VAS at 4, 12 and 24 weeks were 4, 1.5 and 5, respectively. In the Tamoxifen group it was 4, 1 and 3 after treatment for 4, 12 and 24 weeks. On comparison, Centchroman and Tamoxifen both had better pain relief than danazol at 24 weeks (p <0.001) while Centchroman and Tamoxifen had comparable results (p >0.05) despite Centchroman having a lower mean VAS score.Conclusions: Mild cyclical mastalgia can be treated with reassurance and lifestyle measures. Moderate to severe mastalgia usually require drug treatment. Centchroman, Danazol and Tamoxifen are effective. Centchroman appears to have better pain relief relative to the rest.
Cellulitis left lower leg secondary to Pseudomonas aeruginosa bacteremia: case of community -acquired infection
Authors: Makhdoomi Mahmood A. , Abdo Ehab M. , Ilyas Syed O. , Sedik Alaa M. , Elsayed Ashraf A. , Alotaibi Meshal S.
Published: January 2019

The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, usually from acute infection. Pseudomonas aeruginosa is a gram-negative bacillus that causes wide spectrum clinical infections. However, it is most frequently associated with hospital-acquired infection. Authors are presenting a case report of 45 years old Saudi male who presented initially with redness and hotness in the mid of right lower leg gradually increased with development of vesiculous bullae, scaling and sloughing of overlying skin. Pseudomonas aeruginosa was identified from the case, though it was not a usual suspected organism. It might be due to community-acquired infection. Patient was treated conservatively with I/V antibiotic and local hygienic methods including dressing with vaseline (bactigrass) and topical antibiotics. Patient improved and discharged with complete resolution of cellulitis
Low-grade myofibroblastic sarcoma of retroperitoneum: a rare case
Authors: Choudhary Suresh K. , Gupta Shalu , Bansal Somendra , Kumar Narender
Published: January 2019

Low-grade myofibroblastic sarcoma (LGMFS) is an uncommon tumor which develops mainly in the bone or soft tissues of the head and neck region, trunk, or extremities and extremely rarely found in the abdominal cavity. The rarity of the disease and its low-grade features make an accurate diagnosis difficult in most cases. We recently encountered a giant LGMFS which had developed in retroperitoneum and surgically resected with gratifying results. An 18 years old female presented with complaint of left sided abdominal pain since 8 months and left sided abdominal lump since 5 months. Imaging examinations revealed retroperitoneal soft tissue mass, and surgical treatment was scheduled. During operation, a tumor about 20x18x15cm in diameter with its anterior aspect covered with the pancreas, mesocolon and splenic flexure of colon with densely adhered to splenic vessels and left renal vessels was found. The tumor had firm adhesions to the surrounding tissues, and it was excised with concomitant distal pancreato-splenectomy, left nephrectomy and resection of splenic flexure of colon with colo-colic anastomosis. Histopathologically, fusiform cells were arranged in a complicated or storiform pattern, and immunohistochemical staining revealed that the tumor was positive for vimentin and focally positive for α-smooth muscle actin (SMA), negative for desmin, CD34, CD117, EMA, DOG-1 and S-100. Diagnosis of LGMFS was made. During 6 months follow up patient is asymptomatic and ultrasound abdomen is normal. In case of LGMFS, favorable prognosis can be attained by complete resection of the primary lesion and regular follow up of patient by physical examination and imaging modality.
Experimental Investigation to Enhance the Performance of High Speed Reduction Gearbox using Nano Blended Lubricants
Authors: Dharma Rao Isai , Prasad C. L. V. R. S. V. , Santarao K.
Published: January 2019

The sliding motion between worm and worm wheel is the inherent factor that makes the worm and worm wheel drives less efficient among all the gear drives. Efficiency of these gears varies between 40 to 90%. They need good lubricants, which has high heat dissipation capacity and low coefficient of friction for improving the efficiency. The lubricants considered in the current investigation play a significant role in decreasing the power losses in gearbox besides the geometry of the gears. Nano blended lubricants are found to have efficient tribological and thermal physical properties such as, less frictional coefficient and high heat transfer coefficient. Al2O3 Nano particles of 30 nm size dispersed in SAE 140 mineral oil at different volume fractions resulted decrease in frictional coefficient and found varying from 0.1 to 0.5% nano particle volume fractions. Further, heat transfer coefficient is enhanced by 46.35% for volume fraction of 0.5% and also temperature rise of nano blended lubricant was found to be less than that of base lubricant. The overall efficiency of the selected gearbox with which the experimentation has been done was found to be increased with usage of nano blended lubricant. The performance of the gearbox using nano lubricant at 0.5 volume percent is found improved by 4.85 and 7.86% at operating temperatures 35 and 60oC, respectively compared to the performance of the gearbox using base lubricant.
Fenugreek (Trigonellafoenum-Graecum L) Seed Phytochemicals Protect DNA from Free Radical Induced Oxidative Damage and Inhibit Dipeptidyl Peptidase-IV an Enzyme Associated with Hyperglycemia
Authors: Sreerama Yadahally Nareppa , Rachana MA
Published: January 2019

Fenugreek (Trigonellafoenum-graecum L.; methi) seeds and leaves are used in Asia, Africa, and Mediterranean countries for their nutritional and therapeutic value. It is an ingredient in many traditional Unani and Ayurvedic medicinal systems in India and proven to be very effective in managing blood glucose homeostasis. However, there is a dearth of information on the biochemical rationale for its use in the management of diabetes. In this study, protective effects of fenugreek seed phytochemicals on oxidative stress and inhibition of dipeptidyl peptidase-IV (DPP-IV), a key enzyme associated with diabetes were evaluated. Compositional analysis of phenolics by HPLC revealed that gallic and ferulic acids were the major phenolic acids, and myricetin and rutin were predominant flavonoids in phenolic extracts of fenugreek seeds. Trigonelline content in alkaloid extract was quantitatively determined by reverse phase HPLC and found to be 8.6 mg/g. Alkaloid extract showed superior radical scavenging and metal chelating activities. Besides, these phytochemical extracts also prevented OH• radical-induced DNA damage. Michaelis-Menton and Line weaver-Burk derivations were applied to establish modes of inhibition of DPP-IV activity. Phenolic and alkaloid extracts inhibited DPP-IV activity by mixed non-competitive and non-competitive inhibition mechanisms, respectively. Inhibitory constants of enzyme inhibitor complexes indicate strong affinity of phenolic (Ki, 34.93 ± 0.14 μg) and alkaloid extracts (Ki, 32.3 ± 4.8 μg) for DPP-IV. These results suggest that isolated phytochemicals have the potential as lead compounds for the development of DPP-IV inhibitors to control hyperglycemia and manage diabetes.
Análisis de la competencia en la industria cementera en México
Authors: De la Garza Garza Óscar Javier , Arteaga García Julio César
Published: January 2019

Hay sectores o industrias que son claves en la economía de un país; como ejemplos están las telecomunicaciones, el transporte, la banca comercial, la construcción, el energético, entre otros. En nuestro país, estos mercados tienen características de oligopolios por lo que, al haber pocas empresas, existe la posibilidad de que éstas se coludan y eviten la competencia, cargando precios relativamente altos. Este trabajo analiza la competencia en la industria cementera en México utilizando el enfoque paramétrico de la llamada Nueva Organización Industrial Empírica. Aunque los resultados no son robustos, no se puede descartar que la competencia sea de tipo Stackelberg; tampoco se puede descartar que las empresas cementeras en México se comporten como en el modelo de Cournot.
Propuesta de modelo multicriterio innovador para el análisis del proyecto de inversión en una planta de tratamiento de aguas
Authors: Chew Hernández Mario Luis , Velázquez Romero Verónica , Díaz Téllez Rebeca , Viveros Rosas Leopoldo
Published: January 2019

Actualmente, las decisiones de negocios deben tomarse cuidadosamente, usando toda información disponible y teniendo claras las propias preferencias. Una Escuela Privada tiene por objetivo último las utilidades; sin embargo, el impacto del logro de objetivos de menor nivel (por ejemplo: académicos o ambientales), sobre el objetivo último, no es fácil de cuantificar. A pesar de ello, la evaluación de toda alternativa debe referirse al objetivo último, por lo que se debe cuantificar primero su impacto en los objetivos menores y luego proyectar éstos hacia el objetivo último. Esto requiere analizar y estructurar los objetivos del decisor. En este trabajo, con base en el Pensamiento Enfocado a Valores de Keeney, se desarrolla un modelo que cumple estos requisitos, para evaluar la factibilidad de una Planta de Tratamiento en una Escuela Privada. El uso de modelo se ilustra con un caso de estudio, que se complementa con un análisis de sensibilidad.
Online focus group discussions: An attractive approach to data collection for qualitative health research
Authors: Rivaz Mozhgan , Shokrollahi Paymaneh , Ebadi Abbas
Published: January 2019

Data collection is a centerpiece in qualitative research. The use of multiple sources in data collection can improve conceptual interest of a qualitative inquiry and make it interesting.  Online focus groups (OFGs) as a complementary choice to make the research project easier and engaging. Selection of the most appropriate method of data collection is essential for ensuring the trustworthiness.
This commentary is noted to important issues involved in using OFG discussions for data collection in qualitative health research. In order to determine the suitability of data collection techniques, qualitative researchers are recommended for analysis the question, the research context, the preference of participants, technical issues, the advantages and disadvantages of each method, and provide authentic data to enrich their project by applying innovative approaches.
Auditing of enteral nutrition nursing care in critical care patients
Authors: Al-Jalil Tahereh , Gray Golbahar , Rasouli Maryam , Hoseini-Azizi Tooba , Hejazi Sima-Sadat
Published: January 2019

Background & Aim: Enteral nutrition standards noncompliance is one of the factors that threatens patient safety.  Auditing is an important part in quality improvement processes. The aim of this study was to determine enteral nutrition nursing care conformity rate with standards in the critical care units.
Methods & Materials: In this descriptive study, 400 enteral feeding nursing care were assessed via time and event sampling methods. The tool was a researcher made check list in three fields: pre-feeding, feeding, and post feeding nursing care. Content validity and inter-rater coefficient reliability were calculated for checklist. The obtained data were analyzed using descriptive statistics.
Results: The most conformity rate with standards was in feeding (86%), pre-feeding (3/8 %) and post feeding (2/3%) field, respectively. Determination of PH (100%) and accurate gastric residual volume (99.8%) in pre-feeding field, disconnection of the syringe from catheter after feeding, in feeding filed and accurate documentation of the care (99.3%) in post feeding field, were not implemented in the most of cases.
Conclusion: Enteral nutrition nursing care is far from standards in the pre and post feeding fields. Lack of the clear clinical guidelines, shortage of nursing staff and equipment and inadequate training are relating factors.
Resiliencia comunitaria: Defensa del agua y del territorio en la cuenca del río Sumapaz, Colombia
Authors: Botia Flechas Clara Judith , Preciado Jair
Published: January 2019

La defensa del agua y del territorio en la cuenca del río Sumapaz se manifiesta como una expresión de resiliencia comunitaria, en la medida en que evidencia la apropiación que tienen las comunidades del agua y de los conflictos socioambientales de su territorio; situación que logra empoderarlas como agentes de cambio. Por tanto, el objetivo central de este artículo es analizar los procesos de defensa del agua, acontecidos en la cuenca del río Sumapaz en el periodo comprendido entre los años 2012 – 2017, en relación con los proyectos de explotación petrolera y de generación de energía hidroeléctrica; desde la resiliencia comunitaria. La metodología se basó en la revisión documental del contexto histórico y los eventos recientes y la aplicación de entrevistas semiestructuradas a actores clave. La investigación evidenció la existencia de una autoestima colectiva, una cohesión social y una identidad cultural como pilares fundamentales que se entrelazan y dan soporte a la resiliencia comunitaria en el territorio de la cuenca.
Few Open Access Journals are Plan S Compliant
Authors: Frantsvåg Jan Erik , Strømme Tormod Eismann
Published: January 2019

Much of the debate on Plan S seems to concentrate on how to make toll access journals open access, taking for granted that existing open access journals are Plan S compliant. We suspected this was not so, and set out to explore this using DOAJ's journal metadata. We conclude that an overwhelmingly large majority of open access journals are not Plan S compliant, and that it is small HSS publishers not charging APCs that are least compliant and will face major challenges with becoming compliant. Plan S need to give special considerations to smaller publishers and/or non-APC-based journals.
Dark Proteome Database: Studies on Dark Proteins
Authors: Perdigão Nelson
Published: January 2019

The dark proteome as we define it, is the part of the proteome where 3D structure has not been observed either by homology modeling or by experimental characterization in the protein universe. From the 550.116 proteins available in Swiss-Prot (as of July 2016) 43.2% of the Eukarya universe and 49.2% of the Virus universe are part of the dark proteome. In Bacteria and Archaea, the percentage of the dark proteome presence is significantly less, with 12.6% and 13.3% respectively. In this work, we present the map of the dark proteome in Human and in other model organisms. The most significant result is that around 40%- 50% of the proteome of these organisms are still in the dark, where the higher percentages belong to higher eukaryotes (mouse and human organisms). Due to the amount of darkness present in the human organism being more than 50%, deeper studies were made, including the identification of ‘dark’ genes that are responsible for the production of the so-called dark proteins, as well as, the identification of the ‘dark’ organs where dark proteins are over represented, namely heart, cervical mucosa and natural killer cells. This is a step forward in the direction of the human dark proteome.
Relación entre los factores sociodemográficos y la función sexual en pacientes con Hipertensión Arterial
Authors: Valdez-Montero Carolina , Gastélum-Morales Maria Gisela , Ahumada-Cortez Jesica Guadalupe , Gámez-Medina Mario Enrique , Soto-Montero Fabiola Elizabeth
Published: February 2019

Objetivo: Determinar la relación de los factores sociodemográficos y la función sexual en pacientes con HTA. Método: Diseño descriptivo correlacional, La muestra estuvo conformada por 148 pacientes con HTA de la unidad de medicina familiar en el área rural del municipio de Ahome. Resultados: Las mujeres mostraron descenso en la excitación (M= 2.12, DE= .26) y la lubricación (M= 2.19, DE= .20). El nivel de disfunción eréctil fue entre media (36.2%) y media moderada (26.3%). Casi todos los participantes presentaron disfunción sexual secundaria al tratamiento con psicofármacos. La función sexual femenina y masculina se presentaron correlaciones negativas y significativas con la edad (rs= -.477, rs= -.700, p< .01), tiempo de diagnóstico de HTA (rs= -.399, rs= -.417, p< .01), tiempo de relación sentimental o de pareja (rs= -.382, rs= -.618, p< .01) y número de hijos (rs= -.368, rs= -.610, p< .01) y mostró relación positiva y significativa con la escolaridad (rs= .435, rs= .314, p< .01). La disfunción sexual secundaria al tratamiento con psicofármacos se encontró relación positiva y significativa con la edad (rs= .429, p< .01), el tiempo de diagnóstico (rs= .369, p< .01) y de relación sentimental (rs= .297, p< .01) y con el número de hijos (rs= .326, p< .01) y relación negativa y significativa con la escolaridad (rs= -.207, p< .05). Conclusiones: El padecimiento y el tratamiento de la HTA repercuten en la función sexual de las mujeres y hombres.
Alternative analyses of market value added: a case study of Thailand
Authors: Sareewiwatthana Paiboon , Wanidwaranan Phasin
Published: January 2019

This paper examines the market value added (MVA) of listed companies in Thailand. It is known that the major drawbacks of MVA are size and market return effects. Using the two additional approaches to improve MVA study – MVA change, and the market return adjusted of three-year growth rate of MVA – the better interpretations of MVA in the Thai market during 1999–2018 are obtained. The first approach reduces the market capitalization bias, while the second diminishes the effect of the overall market trend and the stability of firm’s current performance. This study finds that when the two alternative techniques are applied, the annual results of the MVA rankings are not consistent with those of the traditional MVA and thus lead to a new insight into such indicator. Therefore, this study advances the understanding of the market value added and value creation indicators.