bluuebunny/crossref_metadata_2025 huggingface dataset:
On the Track of the Szekler Village Tízes The Model-Like Potential of the Szekler Village Tízes on the Eve of the 21st Century
Authors: Ambrus Tünde
Published: February 2018

The object of this study is the existence of the village tízes (organization in structures by ten) as space-specific elements in Szeklerland and the social problems at the turn of the centuries (involving the population, the community, the culture, and the economy). The study is the result of a historical-geographical survey of the cultural space in Szeklerland within a larger research. The main purpose is to make an attempt to form a historical, system-based perspective, make people aware of the material and spiritual value of the Szekler tízes as well as contribute to the subsistence of the tízes and the reinterpretation of the notion of value in the 21st century, using my own means and modalities. The subsistence of the Szekler village tízes is not required by the subsistence or restoration of the romantic, spiritual goods or the community organization but by the necessities of the entire community.
Old and New Criteria for the Governance of Political and Economic Structures on the Basis of the Bible and the Quran
Authors: Varga Norbert , Szikra Andrea
Published: February 2018

This study presents a sociological analysis of the Holy Books of two world religions (the Bible and the Quran) since, according to prognoses and risk analyses, a political, economic, cultural, and religious confrontation between the world religions will be unavoidable. Special economic and political aspects also contribute to the up-to-datedness of the topic in the democratic world; in fact: the economic crisis at the beginning of the 21st century, the difficulties of managing the crisis with traditional micro- and macroeconomic tools as well as the Europe-wide issue of migration processes. These challenges have directed our attention to alternative economic solutions and policy options, including theories on ethical basis. Modern academic discourse has recently started to direct research at leadership skills as acknowledged forms of talent. The priority of moral talent is never disputed in the Bible and the Quran, more so by certain leaders holding political or economic positions.
Clinically relevant discrepancies between different rheumatoid factor assays
Authors: Falkenburg Willem J.J. , von Richthofen Helen J. , Koers Jana , Weykamp Cas , Schreurs Marco W.J. , Bakker-Jonges Liesbeth E. , Haagen Inez-Anne , Lems Willem F. , Hamann Dörte , van Schaardenburg Dirkjan , Rispens Theo
Published: February 2018

Background:

Accurate measurements of rheumatoid factors (RFs), autoantibodies binding IgG, are important for diagnosing rheumatoid arthritis (RA) and for predicting disease course. Worldwide, various RF assays are being used that differ in technique and target antigens. We studied whether assay choice leads to clinically important discrepancies in RF status and level.

Methods:

RF measurements using four commercial RF assays were compared in 32 RF+samples. Using enzyme-linked immunosorbent assays (ELISAs), the influence of the target antigen source – human IgG (hIgG) versus rabbit IgG (rIgG) – on measured RF levels was investigated in arthralgia patients and RA patients.

Results:

Substantial discrepancies were found between RF levels measured in the four commercial assays. Six samples (19%) with RF levels below or slightly above the cutoff in the rIgG-based Phadia assay were RF+in three assays using hIgG as the target antigen, some with very high levels. Direct ELISA comparisons of RF reactivity against hIgG and rIgG estimated that among 173 ACPA+arthralgia patients, originally RF negative in rIgG-based assays, up to 10% were single positive against hIgG. Monoclonal RFs binding to hIgG and rIgG or hIgG only supported these findings. In a cohort of 69 early RA patients, virtually all RF responses reacted with both targets, although levels were still variable.

Conclusions:

The use of RF assays that differ in technique and target antigen, together with the different specificities of RF responses, leads to discrepancies in RF status and levels. This has important consequences for patient care if RA diagnosis and disease progression assessments are based on RF test results.
Quantitative urine test strip reading for leukocyte esterase and hemoglobin peroxidase
Authors: Oyaert Matthijs N. , Himpe Jonas , Speeckaert Marijn M. , Stove Veronique V. , Delanghe Joris R.
Published: February 2018

Background:

Recently, urine test strip readers have become available for automated test strip analysis. We explored the possibilities of the Sysmex UC-3500 automated urine chemistry analyzer based on complementary metal oxide semiconductor (CMOS) sensor technology with regard to accuracy of leukocyte esterase and hemoglobin peroxidase results. We studied the influence of possible confounders on these measurements.

Methods:

Reflectance data of leukocyte esterase and hemoglobin peroxidase were measured using CMOS technology on the Sysmex UC-3500 automated urine chemistry analyzer. Analytical performance (imprecision, LOQ) as well as the correlation with white blood cell (WBC) and red blood cell (RBC) counts (Sysmex UF-5000) were studied. Furthermore, the influence of urinary dilution, haptoglobin, pH and ascorbic acid as confounders was determined.

Results:

Within- and between-run imprecision (reflectance signal) ranged from 1.1% to 3.6% and 0.9% to 4.2% for peroxidase and 0.4% to 2.5% and 0.4% to 3.3% for leukocyte esterase. Good agreement was obtained between the UF-5000 for RBCs and peroxidase reflectance (r=0.843) and for WBCs and leukocyte esterase (r=0.821). Specific esterase activity decreased for WBC counts exceeding 100 cells/μL. Haptoglobin influenced the peroxidase activity, whereas leukocyte esterase and peroxidase activities showed a pH optimum between 5.0 and 6.5. A sigmoidal correlation was observed between urinary osmolality and peroxidase activity.

Conclusions:

CMOS technology allows to obtain high quality test strip results for assessing WBC and RBC in urine. Quantitative peroxidase and leukocyte esterase are complementary with flow cytometry and have an added value in urinalysis, which may form a basis for expert system development.
Use of eculizumab in pregnancy-associated atypical hemolytic uremic syndrome
Authors: Misal Meenal , Gupta Megha , Platt Lawrence D. , Silverman Neil S. , Han Christina S.
Published: February 2018

Pregnancy-associated atypical hemolytic uremic syndrome (p-aHUS) is a rare disorder, with an estimated incidence of 1 in 25,000 pregnancies [Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, et al. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol. 2010;21:859–67.]. Unlike classic hemolytic uremic syndrome (HUS), aHUS is not related to Escherichia coli 0157:H7 infections. Rather, it arises from uncontrolled alternative complement pathway activation leading to diffuse endothelial damage. The formation of the resulting fibrin and platelet microthrombi in the vasculature leads to hemolysis, thrombocytopenia and ischemic end-organ damage in the form of acute kidney injury [Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med. 2009;361:1676–87; Legendre CM, Licht C, Muus P, Greenbaum LA, Babu S, Bedrosian C, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013;368:2169–81; Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60; Shen YM. Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome. Thromb J. 2016;14(Suppl 1):19.]. Triggers for hyperactivation of the complement pathway include infection, inflammation, malignancy, endothelium-affecting drugs, maternal-fetal hemorrhage and pre-eclampsia [Shen YM. Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome. Thromb J. 2016;14(Suppl 1):19.]. Thirty percent of individuals with aHUS are found to have mutations in the genes encoding complement regulatory proteins, such as protein factor H, complement factor I and complement 3 [Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med. 2009;361:1676–87; Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60.]. Outcomes of an untreated aHUS are poor: up to 50% of patients with aHUS progress to end-stage renal disease within a year and 25% die during the acute phase [Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60; Laurence J, Haller H, Mannucci PM, Nangaku M, Praga M, Rodriguez de Cordoba S. Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis. Clin Adv Hematol Oncol. 2016;14(Suppl 11):2–15.]. We present an unusual case of a 37-year-old primigravida who developed p-aHUS in the setting of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. She was successfully treated with a relatively novel medication; eculizumab, a terminal complement inhibitor. In contrast to previous reports of long-term treatment, she received a total of six doses of eculizumab and remained in remission at 12 months postpartum.
Uterine rupture of a non-communicating rudimentary horn pregnancy with resultant successful outcome of an extremely premature baby born at 24 weeks of gestation
Authors: Pegu Satyaranjan , Deb Bakul , Peters Tara , Rattray Darrien
Published: February 2018

Mullerian anomalies occur in about 0.5% of reproductive-aged women; many remain asymptomatic only being discovered during surgery or on imaging done for unrelated reasons. These result from the abnormal formation, fusion or resorption of the mullerian duct during development. A unicornuate uterus with a rudimentary horn is one of the rarer subtypes, with such anomalies making up about 5% of all mullerian anomalies. Pregnancy in a non-communicating uterine horn (NCUH) is extremely rare, with an incidence between 1:100,000 and 1:140,000. There is a high risk of uterine rupture if pregnancy occurs in a non-communicating uterine horn. We present here a case of a non-communicating rudimentary horn pregnancy, with a successful outcome.
Littoral cell angioma with splenic rupture in pregnancy
Authors: McHugh Ann , O’Gorman Catherine , Cooley Sharon , McEntee Gerry , Burke Naomi
Published: February 2018

Splenic rupture in pregnancy is a rare event. It is generally due to trauma or an underlying splenic pathology. Timely diagnosis and intervention of splenic rupture is essential given the high rates of associated maternal and fetal morbidity and mortality. This case illustrates a 38 year old lady in the third trimester of pregnancy who presented with maternal collapse and a non-reassuring foetal heart rate tracing following a fall at home one week previously. A massive hemoperitoneum was identified at caesarean section and a splenectomy was performed. Histological examination revealed a littoral cell angioma of the spleen. This vascular tumour arising in the splenic red pulp sinuses is a rare entity and specific immunophenotypic features help distinguish it from other vascular tumours of the spleen. Both trauma and an underlying splenic pathology led to splenic rupture in this unique case.
Reproduction abilities of Ips typographus (L.) (Coleoptera: Curculionidae, Scolytinae) in the stands damaged by the wind in 2013 in the Kościeliska Valley (Tatra National Park)
Authors: Grodzki Wojciech , Fronek Wojciech Gąsienica
Published: February 2018

At the end of 2013, strong wind destroyed spruce stands on large areas of Kościeliska Valley in Tatra Mts. in Poland. In 2015–2017, 304 bark samples were collected from 106 spruces; 25 cm × 25 cm large samples were taken from 2 or 4 sections of infested trees in July/August each year. The infestation density, sex ratio, length of maternal galleries, number of progeny and impact of natural enemies were recorded. The infestation density in individual years was 0.79–0.86 mating chambers per dm2, the average length of maternal gallery (55.2–56.6 mm) did not differ between years, The average number of progeny per female from 3-year pooled data was 18.22, the highest in 2015 (27.4) then collapsed to 15.5–16.8. The gallery systems with 2 females, in which the reproduction success was the highest, dominated (62.6%). The frequency of parasitoids or entomopathogens was very low (2–20% mortality rate in 19 bark samples). Possible reasons of relatively low reproduction success regardless generally favourable breeding conditions and its collapse after first year, such as high infestation density and low survival rate of larvae because of climatic conditions (drought), are discussed. Taking into account the described population features, very intense tree mortality and mechanisms known from the other wind events, further development of the outbreak can be expected in this area.
Relationship between particular dendrobiometrical indicators of natural European beech (Fagus sylvatica L.) dendrocenoses in Central Balkan Range
Authors: Ferezliev Angel
Published: February 2018

In parallel studies, different regression models were tested to identify relationships between particular dendrobiometrical indicators on two sample plots representing forests dominated by the European beech in the Central Balkan Range (Bulgaria). The presence of incomplete multicollinearity was studied through correlation matrix for factor variables. To avoid multicollinear negative impact, step multiple regression was applied and adequate regression equations of the relationships under consideration were formulated. The results of statistical analysis confirmed that the link between the investigated indicators is strong and that the ’cloud‘ data show some ’sphericity‘ and distribution close to normal. In one of the sample plots, one major volume-forming factor – height does not participate in the obtained regression equation, so it is not possible to estimate its influence. By testing linear and several nonlinear regression dependencies and by mediating widely used statistical criterions for model selection, the optimal linear model of the considered link was chosen.
Characteristics of physical properties in soil profiles under selected introduced trees in the Nature Reserve Arboretum Mlyňany, Slovakia
Authors: Polláková Nora , Šimanský Vladimír , Jonczak Jerzy
Published: February 2018

The relationship between introduced trees roots and soils in which they grow is the most important factor influencing the adaptation, growth and health of these trees. Therefore, the objective of this study was to identify which physical soil properties enhance or limit the vitality of the studied introduced trees in the Arboretum Mlyňany. Soil properties were studied in seven soil profiles under dense monocultures of Chamaecyparis lawsoniana, Liriodendron tulipifera, Juniperus Chinensis, Thuja orientalis, Thuja plicata, Picea orientalis and Pinus nigra. The results showed that all stagnic horizons had exceeded the limit values of total porosity and bulk density, hence these horizons were compacted. Based on the soil and climatic requirements of the examined trees we conclude that the soil properties of their sites in arboretum are suitable for: Chamaecyparis lawsoniana, Liriodendron tulipifera, Thuja orientalis and Pinus nigra. Nevertheless, physical properties in profiles under Picea orientalis and Juniperus Chinensis do not permit rapid drainage of water, what is unfavourable for healthy development of these two species; while Thuja plicata demanding high moisture supply is grown on soil with high coarse porosity, a prerequisite of fast rainwater drainage. However, since none of the studied introduced trees had suffered from physiological disorders or diseases, they may be declared acclimatized well in the soil-climate conditions described in this study.
Adverbial Markers of Modality in Norwegian L1 and L2 Conversations
Authors: Horbowicz Paulina
Published: February 2018

The aim of this paper is to investigate how second language speakers of Norwegian (henceforth Norwegian L2 speakers) differ in their use of modality expressions from native speakers (L1 speakers). As modality is a very broad subject, the main focus of the study is limited to one-word modal adverbs, such askanskje‘maybe’, and modal particles such asjo. The study compares the frequency of using different types of modal adverbials by L1 and L2 speakers, and their syntactic position. The implications of the study are two-fold. First of all, it is to contribute to the studies of the field of modality in Norwegian. The second implication is didactic, as describing the use of modal adverbials in Norwegian conversation can help devise right teaching materials to allow second language users achieve a more native-like competence in this respect.
Weighted boundedness of multilinear singular integral operators with non-smooth kernels for the extreme cases
Authors: Kuang Weiping
Published: February 2018

The weighted boundedness properties of multilinear operators associated to singular integral operators with non-smooth kernels for extreme cases are obtained.
Flow-mode biodiesel production from palm oil using a pressurized microwave reactor
Authors: Safieddin Ardebili Seyed Mohammad , Ge Xinyu , Cravotto Giancarlo
Published: February 2018

The factors that influence microwave-assisted biodiesel production reactions have been analyzed in this investigation. The studied parameters included microwave (MW) power, irradiation time, and reactor pressure. The response surface method was used to optimize the reaction conditions. The conversion for the 6:1 methanol/oil molar ratio and 1% catalyst ranged from 68.4% to 96.71%. The optimized conditions were found to be 138 s of MW irradiation at 780 W and 7 bar pressure. The conversion at this point was 97.82%. Biodiesel yield increased at higher radiation times (90–130 s) and pressures (5–7 bar). Results show that MW power and irradiation time have significant effects at the 1% level, whereas pressure had significant effects at the 5% level on biodiesel production in this range. The major properties of the palm oil biodiesel produced herein have met the requirements of the EN 14214 methyl ester standard.
A straightforward proof of Carleman estimate for second-order elliptic operator and a three-sphere inequality
Authors: Baldassari Lorenzo , Vessella Sergio
Published: February 2018

In this paper we provide a simple proof of a Carleman estimate for a second-order elliptic operator P with Lipschitz leading coefficients. We apply such a Carleman estimate to derive a three-sphere inequality for solutions to equation

P
⁢
u

=
0

{Pu=0}

.
The Roman Road System in the Golan: Highways, Paths and Tracks in Quotidian Life
Authors: Pažout Adam
Published: February 2018

Roman Imperial Roads (highways) built, maintained and organized by the Roman army and provincial authorities were studied in the Golan Heights since Schumacher’s surveys in the 1880s. However, most of these were obliterated by building and agricultural activity since the beginning of the 20th century. Local ancient road system, linking individual communities and their agricultural land was never studied, since it barely leaves a trace in archaeological record. This paper presents reconstruction of inter-provincial highways passing through the southern Golan Heights, and local road system in GIS using cumulative focal mobility network (CFMN) analysis. The CFMN provides outline of natural corridors of movement in the region. From CFMN it is possible to extract path with higher mobility potential which will be tested against present evidence for Roman Imperial Highways, since it is assumed that corridors with high mobility potential would be suitable place for construction of (inter-)provincial road. Path with lower mobility potential might indicate local road system, so it would be possible to connect agricultural communities with the land they exploited; which in turn may have implications for site prediction and site-catchment analysis exploring quotidian movement of people and goods in the landscape. Two case studies in this respect are presented: the city of Hippos and settlement of es-Safuriyye.
Economic Conditions in the Area Around the Sea of Galilee in Pre-Hellenistic Times
Authors: Zwickel Wolfgang
Published: February 2018

In a landscape archaeology project all the fertile fields around the Sea of Galilee (an area of 50 × 30 km) were mapped. The whole territory was subdivided in 5 regions: Jordan valley, Lower Galilee, Upper Galilee, Golan and Transjordanian Hill Country. Additionally all ancient sites from the Neolithic to the Persian period, which are mentioned in archaeological literature, were collected – all together more than 300 sites. These data allow a reconstruction of the economic conditions in antiquity in the area around the Sea of Galilee. Landscape archaeology clearly demonstrates that the economic basis may have been completely diverse in the five sub-regions, and also during different times. Agriculture played a major role in the economy of ancient people. During some periods and in some regions people lived in the midst of the fields, while in other periods they settled at the edges in order not to waste valuable farmland. On the other hand the position of some sites in some periods clearly demonstrates that trade played a major role for the income of the settlers, or basalt mining and working. Streets can be reconstructed, and our methodological approach allows new insights in the economy of this area
Publishing Landscape Archaeology in the Digital World
Authors: Howry Jeffrey C.
Published: February 2018

The challenge of presenting micro- and macro-scale scale data in landscape archaeology studies is facilitated by a diversity of GIS technologies. Specific to scholarly research is the need to selectively share certain types of data with collaborators and academic researchers while also publishing general information in the public domain. This article presents a general model for scholarly online collaboration and teaching while providing examples of the kinds of landscape archaeology that can be published online. Specifically illustrated is WorldMap, an interactive mapping platform based upon open-source software which uses browsers built to open source standards. The various features of this platform allow tight user viewing control, views with URL referencing, commenting and certification of layers, as well as user annotation. Illustration of WorldMap features and its value for scholarly research and teaching is provided in the context of landscape archaeology studies.
Evidentiary means in feudal Transylvania. Ordeal By fire (holding a red-hot iron)
Authors: Florin Moldovan Iosif
Published: February 2018

One of the evidentiary means used in medieval legal procedure was the so-called judgment of God, judicium dei, also known as ordeal, from the Latin term ordalium. Ordeals were characteristic of all peoples in their various stages of development. They were based on the belief that divinity could intervene and perform miracles, disregarding the laws of nature, in order to prove one’s innocence. In the Middle Ages ordeals were widespread on the territory of Transylvania, too, the ordeal of fire being one of the most commonly used means of proof. In this paper I will try to show the characteristics of this evidence in relation to others that were used at that time, looking at them through the lenses of the documents of the time and of personal research.
Operational validation of HYDRUS (2D/3D) for capillary barriers using data of a 10-m tipping trough
Authors: Berger Klaus
Published: February 2018

Capillary barriers are an interesting alternative component for cover systems of landfills and contaminated sites. Provided they are sufficiently validated, soil hydrological models could be fast and powerful tools for the dimensioning of capillary barriers. Outflow rates measured in a 10 m long tipping trough for one material combination and two slopes from stationary periods were compared to simulation results of HYDRUS (2D/3D), Version 2.05. The measured outflow rates show a typical pattern with slope-dependent threshold values indicating the efficiency of the capillary barrier. This flow pattern could not be reproduced with HYDRUS (2D/3D) that for different input setups produced smooth patterns without thresholds. The input setup was varied for different soil hydraulic models (van Genuchten-Mualem vs. Brooks-Corey), homogeneous and heterogeneous transport domains (no scaling vs. stochastically distributed scaling factors considering the Miller-Miller similitude), different HYDRUS versions (standard vs. alternative; i.e., with material properties assigned either to finite element nodes or finite elements, respectively), and different lower boundary conditions (seepage face vs. free drainage). Differences between measured and simulated outflow patterns could be caused by the measurements, the application of the model, or by the model itself. The van Genuchten-Mualem model may not be suitable to describe the soil hydrological relationships of these particular materials. The reason for the mismatch, however, could not be identified yet.
Zero-divisor graphs of lower dismantlable lattices II
Authors: Patil Avinash , Waphare B. N. , Joshi Vinayak
Published: February 2018

In this paper, we continue our study of the zero-divisor graphs of lower dismantlable lattices that was started in [PATIL, A.—WAPHARE, B. N.—JOSHI, V.—POURALI, H. Y.: Zero-divisor graphs of lower dismantlable lattices I, Math. Slovaca 67 (2017), 285–296]. The present paper mainly deals with an Isomorphism Problem for the zero-divisor graphs of lattices. In fact, we prove that the zero-divisor graphs of lower dismantlable lattices with the greatest element 1 as join-reducible are isomorphic if and only if the lattices are isomorphic.
Crystal structural of 2-amino-4-(3-bromophenyl)-3-cyano-7,7-dimethyl-5-oxo-4H-5,6,7,8-tetrahydrobenzo[b]pyran, C18H17BrN2O2
Authors: Song Jing
Published: February 2018

C18H17BrN2O2, monoclinic, C2/c (no. 15), a = 23.554(2) Å, b = 9.3060(8) Å, c = 15.7691(15) Å, β = 93.372(9)°, V = 3450.5(5) Å3, Z = 8, R
gt(F) = 0.0521, wR
ref(F
2) = 0.1686, T = 293 K.
Crystal structure of [(1,2-bis(dicyclohexylphosphino)-1,2-dicarba-closo-dodecaborane-κ2
P,P′]dibromidonickel(II)), C26H54B10NiBr2P2
Authors: Liguo Yang , Qingyun Liu , Xin Wang , Nana Liu , Yuqiang Dai
Published: February 2018

C26H54B10NiBr2P2, monoclinic, C2/c (no. 15), a = 13.064(7) Å, b = 15.655(8) Å, c = 16.652(9) Å, β = 95.830(7)°, V = 3388(3) Å3, Z = 4, R
gt(F) = 0.0603, wR
ref(F
2) = 0.1364, T = 298(2) K.
Proactive coping as a kind of creative adaptation to a new workplace
Authors: Ślebarska Katarzyna
Published: February 2018

The proactive dimension of human behavior is rooted in one’s need to create and control the environment. Individuals prefer to do things actively and creatively rather than being counteractive. The dynamics of the job market demand that individuals are increasingly independent and proactive, can easily adapt to change, and create their own future. This way of understanding a newcomer’s activity corresponds to proactive coping. The main goal of this study was to investigate the role of proactive coping of workers in a new workplace and in job adaptation outcomes, namely well-being. Data was collected from newly employed workers (N = 172) who agreed to participate in the study within a longitudinal evaluation design (one pre-test and a double post-test) during their first six months in a new workplace. Overall, the study demonstrates that proactive coping improves the adaptation of new employees, costing them less emotionally as they adjust to their new workplace. Additionally, the employees’ pre-entry experience (previously unemployed vs previously employed) moderated the relation between the analyzed variables.
Brundibár – A Children’s Opera: History and Present
Authors: Pirníková Tatiana
Published: February 2018

The paper focuses on the opera Brundibár. The authorial couple – composer Hans Krasa and librettist Adolf Hoffmeister – wrote it in the period of growing interest of artists in pedagogical aspects of the works of art. The changed social climate, however, meant for the work an unplanned journey – during the Second World War it was performed inside the Terezin ghetto by its inhabitants. The human message of the fairy tale story has thus been elevated into a higher symbolic frame – a resistance against the arrogance of power and violence. Especially the post-war era followed this symbolism. The author of the paper contemplates the innovative interpretative levels whose ambition is to cross the traditional performance frame of the work and to find connections with problems of contemporary society.
Interplay of Brain-Derived Neurotrophic Factor and Cytokines in Schizophrenia
Authors: Janicijevic Slavica Minic , Dejanovic Slavica Djukic , Borovcanin Milica
Published: February 2018

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family and plays an important role in neuroplasticity, differentiation and survival of neurons, as well as their function. Neuroinflammation has been explored in the pathophysiology of many mental disorders, such as schizophrenia. Cytokines representing different types of immune responses have an impact on neurogenesis and BDNF expression. Cross-regulation of BDNF and cytokines is accomplished through several signalling pathways. Also, typical and atypical antipsychotic drugs variously modulate the expression of BDNF and serum levels of cytokines, which can possibly be used in evaluation of therapy effectiveness. Comorbidity of metabolic syndrome and atopic diseases has been considered in the context of BDNF and cytokines interplay in schizophrenia.
Effects of activity interruptions by pain on pattern of activity performance – an experimental investigation
Authors: Gatzounis Rena , Schrooten Martien G.S. , Crombez Geert , Vlaeyen Johan W.S.
Published: February 2018

Background and aims:

Suspending an ongoing activity with the intention to resume it again later is a natural response to pain. This response facilitates coping with the pain, but it may also have negative consequences for the resumption and performance of the activity. For example, people with pain problems are often forced to take a break from doing their household chores because of their pain. They might delay resuming their chore, eventually needing longer time to finish it. We investigated how activity interruptions by pain influence the pattern of subsequent activity performance. We expected that when an activity is interrupted by pain (compared to non-pain), people spend longer time away from the activity, need longer time to complete it, and are less motivated to perform it.

Methods:

Sixty healthy volunteers performed an ongoing task that required them to make joystick movements in different directions according to a specific rule. Occasionally, participants received either a painful electrocutaneous stimulus or a non-painful and non-aversive auditory stimulus (between-subjects) as an interruption cue. The interruption cue was followed by the temporary suspension of the ongoing task and the initiation of a different activity (interruption task). The latter required the categorization of cards and had a maximum duration, but participants could also stop it earlier by pressing a button. We measured time away from the (interrupted) ongoing task, total time to complete the ongoing task (including the interruptions) and self-reported motivation to perform both the ongoing as well as the interruption task.

Results:

Groups did not differ in the time away from the ongoing task, total time to complete the ongoing task, or self-reported motivation to perform the two tasks.

Conclusions:

Activity interruptions by pain did not impair the pattern of activity performance more than activity interruptions by non-pain. Potential explanations and suggestions for future research are discussed.

Implications:

Interrupting ongoing activities is a common response to pain. However, activity interruptions by pain do not appear to influence the pattern of activity performance in a different way than activity interruptions by pain-irrelevant external stimuli.
Evaluating the impact of the labor market conditions index on labor market forecasts
Authors: Connolly Laura , Sheehan Alice
Published: February 2018

This paper examines the usefulness of the labor market conditions index (LMCI) in forecasting key labor market variables, particularly unemployment rates. Using a number of models, we compare out-of-sample forecasts of the unemployment rate with the LMCI to those without the LMCI. We also estimate models of the disaggregated unemployment rates by gender, race, and race by gender, with and without the LMCI, to identify disparities in the predictive power of the LMCI for different subgroups. Last, to determine how the LMCI performs in the presence of labor market shocks, we compare the forecasting performance of the LMCI during recessionary periods and expansionary periods. Our results confirm the potential usefulness of the LMCI as a parsimonious forecasting tool; we find that the LMCI generally improves unemployment forecasts. But, disparities exist in the predictive power of the index across subpopulations and the index forecasts slightly better during recessionary periods than expansionary periods.
Explaining Turnout Decline in Post-Communist Countries: The Impact of Migration
Authors: Comşa Mircea
Published: February 2018

Turnout decline in former communist countries has attracted a great deal of scholarly attention. In this paper, I re-test some of the previous hypotheses on new data and I propose a new hypothesis that considers the impact of external migration. Using multivariate regression models on a dataset of 272 presidential and parliamentary elections held in 30 post-communist countries between 1989 and 2012, I have found strong support for the “migration hypothesis”: other things being equal, an increase of migration rate by 1 percentage point reduces voter turnout by around 0.4 percentage points. Most of the previous hypotheses related to causes of turnout decline are supported too.
Determinig the Shape Coefficient A of Groove on the Pen for the Shaft
Authors: Křístek Ivo , Havlík Jiří , Mosler Václav , Daniš Igor
Published: February 2018

This article focuses on creating a diagram for determining the shape coefficient α for a tongue groove on the shaft. Experimental determination of curve diagrams by comparing diagrams and monograms used using FEM calculations.
The Influence of the Size Styles for the Touching Probe for the Roundness of the Deviation
Authors: Mizera Ondrej , Cepova Lenka
Published: February 2018

The article deals with the influence of the sensing touch on the deviation of circularity on the WENZEL LH 65 X3M on 3D machining and using the Metrosoft QUARTIZ R6 software at the VŠB-TU Ostrava Laboratory, Faculty of Mechanical Engineering, Department of Machining, Assembly and engineering metrology. The aim was to analyze the influence of individual sensors on the different lengths of the pin and the diameter of the sensing metod on the accuracy of the measurement of the variance of the circularity.
Aspects of Habitat Use by Birds during Spring in Natural Forests and Non-Native Plantation Forests in the Lower Siret Meadow (Eastern Romania)
Authors: Dragomir Matei-Ionuț , Dragomir Alina , Murariu Dumitru
Published: February 2018

The Lower Siret Meadow forest habitats have been altered from natural structure because of commercial forestry operations, activities that are defining the forest management from previous decades. Afforestation programs aimed to test the introduction of exotic tree species in order to increase wood production and to reduce harvest time intervals. These commercial influences reflect in the decrease of natural forest areas, aspect that could influence the birds presence. Studies on the ecological impact of plantations on birds are scarce, and no studies were found regarding this aspect in the region. Using six different sample areas both in native and non-native tree plantations, we investigated how bird presence is influenced by the support capacity offered by both natural or non-native plantations and which vegetation variables are related to our results. We compared the data from the surveyed areas to relate birds presence and dependence on certain characteristics of the habitats. Our results pointed out that species diversity is higher in natural forests with local tree species and vegetation characteristics like forest canopy density, shrub coverage, and herbaceous layer.
Update on the Geographic Distribution of Lutra lutra at the Romanian Black Sea Coast
Authors: Memedemin Daniyar , Tudor Marian , Cogălniceanu Dan , Skolka Marius , Bănică Gabriel , Rozylowicz Laurențiu
Published: February 2018

We report the occurrence of the European otter (Lutra lutraLinnaeus, 1758) along the entire Romanian Black Sea coast, for the first time. Several sightings were within the harbor and the city of Constanţa, indicating that the otter can accommodate to and tolerate high human impact. The report is based on observations made between 2012 and 2015. The species has been previously reported from all Romanian regions but not from the Black Sea coast. The occurrences reported within this article confirm an extension of the range of this Near Threatened species on the Romanian Black Sea coast, most probably due to the increasing of population size from other sources such as the Danube floodplain.
Biochar Modification, Thermal Stability and Toxicity of Products Modification
Authors: Roupcová Petra , Friedrichová Romana , Klouda Karel , Weisheitelová Markéta , Perďochová Michaela
Published: February 2018

Biochar is a product obtained from processing of waste biomass. The main application of biochar is in soil and environment remediation. Some new applications of this carbonaceous material take advantage of its adsorption capacity use it as a heterogeneous catalyst for energy storage and conversion etc. This contribution describes thermal stability of the original biochar. It discusses biochar modified by chemical and physical methods including a new compound of biochar-graphene oxide. The purpose of the modifications is to increase its active surface to introduce active functional groups into the carbon structure of biochar in relation to fire safety and toxicity of those products.
Individual Differences in Reading Skill Are Related to Trial-by-Trial Neural Activation Variability in the Reading Network
Authors: Malins Jeffrey G. , Pugh Kenneth R. , Buis Bonnie , Frost Stephen J. , Hoeft Fumiko , Landi Nicole , Mencl W. Einar , Kurian Anish , Staples Ryan , Molfese Peter J. , Sevcik Rose , Morris Robin
Published: February 2018

Recent work has suggested that variability in levels of neural activation may be related to behavioral and cognitive performance across a number of domains and may offer information that is not captured by more traditional measures that use the average level of brain activation. We examined the relationship between reading skill in school-aged children and neural activation variability during a functional MRI reading task after taking into account average levels of activity. The reading task involved matching printed and spoken words to pictures of items. Single trial activation estimates were used to calculate the mean and standard deviation of children's responses to print and speech stimuli; multiple regression analyses evaluated the relationship between reading skill and trial-by-trial activation variability. The reliability of observed findings from the discovery sample (n= 44; ages 8–11; 18 female) was then confirmed in an independent sample of children (n= 32; ages 8–11; 14 female). Across the two samples, reading skill was positively related to trial-by-trial variability in the activation response to print in the left inferior frontal gyrus pars triangularis. This relationship held even when accounting for mean levels of activation. This finding suggests that intrasubject variability in trial-by-trial fMRI activation responses to printed words accounts for individual differences in human reading ability that are not fully captured by traditional mean levels of brain activity. Furthermore, this positive relationship between trial-by-trial activation variability and reading skill may provide evidence that neural variability plays a beneficial role during early reading development.

SIGNIFICANCE STATEMENTRecent work has suggested that neural activation variability, or moment-to-moment changes in the engagement of brain regions, is related to individual differences in behavioral and cognitive performance across multiple domains. However, differences in neural activation variability have not yet been evaluated in relation to reading skill. In the current study, we analyzed data from two independent groups of children who performed an fMRI task involving reading and listening to words. Across both samples, reading skill was positively related to trial-by-trial variability in activation to print stimuli in the left inferior frontal gyrus pars triangularis, even when accounting for the more conventional measure of mean levels of brain activity. This finding suggests that neural variability could be beneficial in developing readers.
Association between Social-Cultural and the Utilization of Elderly Integrated Health Services (Posyandu Lansia) in Hamparan Perak Health Center
Authors: Simbolon Pomarida , Simbolon Nagoklan
Published: February 2018

Abstract

Elderly Integrated Health Service (Posyandu Lansia) is an integrated service post for elderly in certain areas that have been agreed upon, which are community driven. A significant elderly population will be accompanied by various problems and will affect various aspects of life especially health. Based on preliminary data, the number of elderly population of 930 people, but only about 230 people or about 24.7% who came to Elderly Integrated Health Services. The purpose of this research was to analyze the association between socio-cultural and the utilization of Elderly Integrated Health Services. The type of this research is the explanatory survey with research population of 160 people and research sample of 60 respondents. Data collection used questionnaire. The results of this study were there was a correlation between tradition (p = 0.000), belief (0.001) with the utilization of Elderly Integrated Health Services.

 

Abstrak

Posyandu Lansia adalah pos pelayanan terpadu untuk orang tua di daerah tertentu yang telah disepakati, yang digerakkan oleh masyarakat. Populasi lansia yang signifikan akan disertai dengan berbagai masalah dan akan mempengaruhi berbagai aspek kehidupan khususnya kesehatan. Berdasarkan data awal jumlah populasi lansia sebanyak 930 orang tetapi yang datang ke posyandu lansia hanya berkisar 230 orang atau sekitar 24,7%. Tujuan dari penelitian ini adalah untuk menganalisis hubungan social budaya dengan pemanfaatan posyandu. Jenis penelitian ini adalah survey explanatory dengan populasi penelitian 160 orang dan sampel penelitian 60 responden. Pengumpulan data dengan menggunakan kuesioner. Hasil penelitian ini menunjukkan ada hubungan antara tradisi (p=0,000), kepercayaan (0,001) dengan dengan pemanfaatan Posyandu.
The Influence of Organizational Culture on Inpatient Staff Performance of QIM Hospital
Authors: Atmojo Agung , Purnomo Imam Purnomo , Muljono Slamet
Published: February 2018

ABSTRACT                                                  

 

Organizational culture plays an important role in stimulating the human resources work spirit. The organizational environment affects staff behavior and appearance, as well as staff performance. QIM Hospital is a new hospital. Therefore, it is needed to know the influence of organizational culture on staff performance in the inpatient staffs of QIM Batang Hospital. Using a quantitative research with the survey method. The population in this research was all in-patient staffs of QIM Batang Hospital. A 51 people as a sample and choosen using simple random sampling. Data taken with questionnaire instrument, then analyzed using simple linear regression. The results showed that organizational culture has a positive and significant effect on staff performance. The influence of organizational culture on staff performance is 64.4% (the coefficient of determination of 0.644).

 

ABSTRAK

 

Budaya organisasi berperan penting dalam  merangsang semangat kerja sumber daya manusia. Lingkungan organisasi mempengaruhi perilaku dan penampilan pegawai serta kinerja pegawai. RS QIM merupakan rumah sakit yang tergolong baru. Sehingga perlu diketahui pengaruh budaya organisasi terhadap kinerja pegawai rawat inap Rumah Sakit QIM Batang. Melalui penelitian kuantitatif menggunakan metode survei. Populasi dalam penelitian ini adalah seluruh pegawai rawat inap Rumah Sakit QIM Batang. Sampel sebanyak 51 orang menggunakan simple random sampling, instrumen kuesioner, dan data dianalisis menggunakan regresi linier sederhana. Hasil menunjukkan bahwa budaya organisasi memiliki pengaruh positif dan signifikan terhadap kinerja pegawai. Pengaruh budaya organisasi terhadap kinerja pegawai sebesar 64,4% (koefisien determinasi sebesar 0,644).
Dysregulated genes and their functional pathways in luteinized granulosa cells from PCOS patients after cabergoline treatment
Authors: Ferrero H , Díaz-Gimeno P , Sebastián-León P , Faus A , Gómez R , Pellicer A
Published: February 2018

Polycystic ovarian syndrome (PCOS) is a common reproductive disorder frequently associated with a substantial risk factor for ovarian hyperstimulation syndrome (OHSS). Dopamine receptor 2 (D2) agonists, like cabergoline (Cb2), have been used to reduce the OHSS risk. However, lutein granulosa cells (LGCs) from PCOS patients treated with Cb2 still show a deregulated dopaminergic tone (decreased D2 expression and low dopamine production) and increased vascularization compared to non-PCOS LGCs. Therefore, to understand the PCOS ovarian physiology, it is important to explore the mechanisms that underlie syndrome based on the therapeutic effects of Cb2. Here, LGCs from non-PCOS and PCOS patients were cultured with hCG in the absence/presence of Cb2 (n = 12). Subsequently, a transcriptomic-paired design that compared untreated vs treated LGCs within each patient was performed. After transcriptomic analysis, functions and genes were prioritized by systems biology approaches and validated by RT-qPCR. We identified that similar functions were altered in both PCOS and non-PCOS LGCs treated with Cb2; however, PCOS-treated LGCs exhibited more significant changes than non-PCOS. Among the prioritized functions, dopaminergic synapse, vascular endothelial growth factor (VEGF) signaling, apoptosis and ovarian steroidogenesis were highlighted. Finally, network modeling showed CASP9, VEGFA, AKT1, CREB, AIF, MAOA, MAPK14 and BMAL1 as key genes implicated in these pathways in Cb2 response, which might be potential biomarkers for further studies in PCOS.