bluuebunny/crossref_metadata_2025 huggingface dataset:
A Scalable Systolic Accelerator for Estimation of the Spectral Correlation Density Function and Its FPGA Implementation
Authors: Li Xiangwei , Maskell Douglas L. , Li Carol Jingyi , Leong Philip H. W. , Boland David
Published: July 2022

The spectral correlation density (SCD) function is the time-averaged correlation of two spectral components used for analyzing periodic signals with time-varying spectral content. Although the analysis is extremely powerful, it has not been widely adopted in real-time applications due to its high computational complexity. In this article, we present an efficient FPGA implementation of the FFT accumulation method (FAM) for estimating the SCD function and its alpha profile. The implementation uses a linear systolic array with a bi-directional datapath consisting of DSP-based processing elements (PEs) with a dedicated instruction schedule, achieving a PE utilization of 88.2%.

The 128-PE implementation achieves a clock frequency in excess of 530 MHz and consumes 151K LUTs, 151K FFs, 264 BRAMs, 4 URAMs, and 1,054 DSPs, which is less than 36% of the logic fabric on a Zynq UltraScale+ XCZU28DR-2FFVG1517E RFSoC device. It has a modest 12.5W power consumption and an energy efficiency of 4,832 MOPS/W, which is 20.6× better than the published state-of-the-art GPU implementation. In terms of throughput, it achieves 15,340 windows/s (15,340 windows/s × 2,048 samples/window = 31.4 MS/s), which is a 4.65× improvement compared to the above-mentioned GPU implementation and 807× compared to an existing hybrid FPGA-GPU implementation.
Aerobic training increases mitochondrial respiratory capacity in human skeletal muscle stem cells from sedentary individuals
Authors: Yeo Reichelle X. , Dijkstra Pieter J. , De Carvalho Flavia G. , Yi Fanchao , Pino Maria F. , Smith Steven R. , Sparks Lauren M.
Published: July 2022

The impact of aerobic training on human skeletal muscle cell (HSkMC) mitochondrial metabolism is a significant research gap, critical to understanding the mechanisms by which exercise augments skeletal muscle metabolism. We therefore assessed mitochondrial content and capacity in fully differentiated CD56+ HSkMCs from lean active (LA) and sedentary individuals with obesity (OS) at baseline, as well as lean/overweight sedentary individuals (LOS) at baseline and following an 18-day aerobic training intervention. Participants had in vivo skeletal muscle PCr recovery rate by 31P-MRS (mitochondrial oxidative kinetics) and cardiorespiratory fitness (V̇o2max) assessed at baseline. Biopsies of the vastus lateralis were performed for the isolation of skeletal muscle stem cells. LOS individuals repeated all assessments posttraining. HSkMCs were evaluated for mitochondrial respiratory capacity by high-resolution respirometry. Data were normalized to two indices of mitochondrial content (CS activity and OXPHOS protein expression) and a marker of total cell count (quantity of DNA). LA individuals had significantly higher V̇o2max than OS and LOS-Pre training; however, no differences were observed in skeletal muscle mitochondrial capacity, nor in carbohydrate- or fatty acid-supported HSkMC respiratory capacity. Aerobic training robustly increased in vivo skeletal muscle mitochondrial capacity of LOS individuals, as well as carbohydrate-supported HSkMC respiratory capacity. Indices of mitochondrial content and total cell count were similar among the groups and did not change with aerobic training. Our findings demonstrate that bioenergetic changes induced with aerobic training in skeletal muscle in vivo are retained in HSkMCs in vitro without impacting mitochondrial content, suggesting that training improves intrinsic skeletal muscle mitochondrial capacity.
[Retracted] Correlation Analysis of Ultrasound Elastography Score with Invasive Breast Cancer and Biological Prognostic Factors
Authors: Fu Q. , Wan F. , Lu Q. , Shao W. , Fu G. , Wang Z.
Published: July 2022

Invasive breast cancer (IBC) is a kind of malignant tumor in which cancer cells have broken through the basement membrane of breast ducts or lobular acini and invaded the stroma. Although ultrasound elastography score (UES) has shown unique advantages in the diagnosis of IBC, its value in the prognosis is not clear. Here, we explored the correlation of UES with IBC and biological prognostic factors. The datum of 86 patients with suspected IBC from January 2018 to December 2021 was collected. UE was applied in the examination of all patients. The lesion tissue of the malignant group was punctured to detect and analyze the expression of biological prognostic factors, including estrogen receptor (E receptor), progesterone receptor (P receptor), and human epidermal growth factor 2 (HER factor 2) and Ki67. The differences in UES under different biological prognostic factors were compared. The receiver operating characteristic (ROC) curve was applied to analyze the diagnostic value of UES of IBC and the expression of biological prognostic factors. Based on the pathological diagnosis results, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of UES in the diagnosis of IBC were analyzed. The correlation of UES with IBC and biological prognostic factors was analyzed by multiple linear regression and Spearman method. ROC analysis showed that the area under the curve of UES for diagnosing IBC and evaluating the expression of P receptor, HER factor 2, and Ki67 were 0.877, 0.704, 0.763, and 0.820, respectively (P＜0.05). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of UES when diagnosing IBC were 92.42%, 90.00%, 91.86%, 96.83%, and 78.26%, respectively. The UES of E receptor expression (positive and negative group) showed no obvious variance (P > 0.05). The UES of P receptors (positive and negative), HER factor 2 (positive and negative), and Ki67 (high and low expression) showed obvious differences (P < 0.05). Multiple linear regression and Spearman indicated UES was significantly correlated with the expression of P receptor, HER factor 2, and Ki67 (P＜0.05). UES has a certain diagnostic value for IBC and is significantly correlated to the expression of P receptor, HER factor 2, and Ki67, which is helpful for evaluating the prognosis of patients with IBC.
Identification of Molecular Mechanism of OSA with Hypertension Based on Multiple Microarray Analysis
Authors: Zhang Xizhu , Jing Gang , Qi Liqing , Ma Mingzhu , Li Liting , Shen Ningning , Guo Zheng , Gao Xiaoling
Published: July 2022

Purpose. OSA is closely associated with hypertension, and both epidemiological and experimental studies have confirmed that OSA is one of the most important independent risk factors for hypertension. The pathological mechanisms by which OSA causes hypertension are not well understood, and in this paper, we explored the molecular mechanisms by which OSA may mediate hypertension at the bioinformatics level. Materials and Methods. We downloaded disease-related datasets from the GEO public database, calculated the differential genes between the two groups of patients by the limma package, and then further constructed the WGCNA network based on the clinical characteristics of patients to explore the important regulatory genes in the disease. Subsequently, ssGSEA was used to explore the potential molecular mechanisms of disease progression and GSVA was applied to analyze the specific signaling pathways. Finally, we performed real-time quantitative PCR (qRT-PCR) to validate these pivotal genes. Results. Three genes were selected as target genes, namely, GPR179, RNF150, and JPH4. The results showed they were strongly correlated with immune cell content that high expression of the three core genes was associated with myogenesis, angiogenesis, oxidation, metabolism, and PI3K/AKT/mTOR pathways. qRT-PCR validated that all three genes have statistically significant differences between the OSA group and OSA combined with hypertension group. Conclusion. Our study provides new evidence for the potential molecular mechanisms of OSA combined with hypertensive disease as well as diagnosis and treatment.
TLR4-SIRT3 Mechanism Modulates Mitochondrial and Redox Homeostasis and Promotes EPCs Recruitment and Survival
Authors: Wang Xiaotian , Yao Weidong , Wang Meihui , Zhu Junhui , Xia Liang
Published: July 2022

The low survival rate of endothelial progenitor cells (EPCs) in vivo which are susceptible to adverse microenvironments including inflammation and oxidative stress has become one primary challenge of EPCs transplantation for regenerative therapy. Recent studies reported functional expression of toll-like receptor (TLR) 4 on EPCs and dose-dependent effects of lipopolysaccharide (LPS) on cellular oxidative stress and angiogenic properties. However, the involved mechanism has not yet been elucidated well, and the influence of TLR4 signaling on EPCs survival and function in vivo is unknown. In the present study, we observed the effects of LPS and TLR4/SIRT3 on EPCs mitochondrial permeability and intracellular mitochondrial superoxide. We employed the monocrotaline-induced pulmonary arteriolar injury model to observe the effects of TLR4/SIRT3 on the recruitment and survival of transplanted EPCs. We found the destructive effects of 10 μg/mL LPS on mitochondrial homeostasis, and cellular viability was mediated by TLR4/SIRT3 signals at least partially, and the TLR4 mediates the early-stage recruitment of transplanted EPCs in pulmonary arteriolar inflammation injury; however, SIRT3 has more contribution to the survival of incorporated EPCs and ameliorated arteriolar remodeling in lung vascular tissue. The study provides insights for the critical role of TLR4/SIRT3 in LPS-induced oxidative stress and mitochondrial disorder in EPCs in vitro and in vivo. The TLR4/SIRT3 signaling is important for EPCs resistance against inflammation and oxidative stress and may represent a new manipulating target for developing efficient cell therapy strategy.
Effect of Radical Laparoscopic Surgery and Conventional Open Surgery on Surgical Outcomes, Complications, and Prognosis in Elderly Patients with Bladder Cancer
Authors: Chen Jiangang , Gu Zhibo , Pan Yongsheng , Zhang Yong , Gu Donghua
Published: July 2022

Background. Bladder cancer is a common malignant tumor of the urinary system in the clinic. It has multiple lesions, easy recurrence, easy metastasis, poor prognosis, and high mortality. Objective. The aim of this study is to investigate the impact of laparoscopic radical cystectomy (LRC) and open radical cystectomy (ORC) on the surgical outcome, complications, and prognosis of elderly patients with bladder cancer. Materials and Methods. One hundred elderly bladder cancer patients who underwent surgery in our hospital from June 2019 to June 2021 were selected for the retrospective study and were divided into 50 cases each in the ORC group and the LRC group according to the different surgical methods. The ORC group was treated with ORC, and the LRC group implemented LRC treatment. The differences in surgery, immune function, recent clinical outcomes, and complications between the two groups were observed and compared. Results. The mean operative time, mean intraoperative bleeding, intraoperative and postoperative transfusion rate, and transfusion volume of patients in the LRC group were statistically significant when compared to the ORC group. The differences in the meantime to resume eating, time to get out of bed, mean number of days in hospital after surgery, and the amount of postoperative numbing analgesics used by patients in the LRC group after surgery were statistically significant compared to the ORC group (

P
<
0.05

). There was no statistically significant difference in the comparison of immune function between the two groups before surgery (

P
>
0.05

), while the comparison of CD8+ and B cells 1 week after surgery of the LRC group was significantly better than that of the ORC group (

P
<
0.05

), and the operation time of the LRC group was longer than that of the ORC group (

P
<
0.05

). Statistical analysis of postoperative complications showed that the overall incidence of postoperative complications in the LRC group was significantly lower than that in the ORC group (16.67% vs. 46.67%) (

P
<
0.05

). Conclusion. LRC has less surgical trauma and intraoperative bleeding, faster postoperative recovery, and fewer postoperative complications, providing some reference for clinical surgery for elderly bladder cancer patients.
Elastic Stress and Plastic Zone Distributions around a Deeply Buried Tunnel under the Nonhydrostatic Pressure
Authors: Liu Shuhong , Fan Jinlu , Wu Chenhao , Zhu Yongquan
Published: July 2022

The elastic stress and the plastic zone are the important mechanical parameters to determine the tunnel support design. Based on Muskhelishvili’s complex variable function, the analytical solution for the elastic stress around a deeply buried noncircular tunnel under the nonhydrostatic pressure is firstly derived. The shape and size of the plastic zone of the surrounding rock mass are then determined by substituting the elastic stresses into the Drucker-Prager yield criterion. Finally, taking a horseshoe-shaped tunnel as an example, the analytical solutions of elastic stress distribution and plastic zone shape around the tunnel under different lateral pressure coefficients are in good agreement with ANSYS numerical solutions. The calculation results show that if the vertical in situ stress exceeds the critical value, with increasing lateral pressure coefficient, the hoop stress at the roof and floor of the tunnel increases significantly and the shape and size of the plastic zone change obviously.
Comprehensive Analysis of Prognostic Value and Immune Infiltration of IGFBP Family Members in Glioblastoma
Authors: Zhong Zhenglan , Xu Xiaoping , Han Shiguo , Shao Yongxiang , Yi Yong
Published: July 2022

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The insulin-like growth factor-binding protein (IGFBP) family is involved in tumorigenesis and the development of multiple cancers. However, little is known about the prognostic value and regulatory mechanisms of IGFBPs in GBM. Oncomine, Gene Expression Profiling Interactive Analysis, PrognoScan, cBioPortal, LinkedOmics, TIMER, and TISIDB were used to analyze the differential expression, prognostic value, genetic alteration, biological function, and immune cell infiltration of IGFBPs in GBM. We observed that IGFBP1, IGFBP2, IGFBP3, IGFBP4, and IGFBP5 mRNA expression was significantly upregulated in patients with GBM, whereas IGFBP6 was downregulated; this difference in mRNA expression was statistically insignificant. Subsequent investigations showed that IGFBP4 and IGFBP6 mRNA levels were significantly associated with overall survival in patients with GBM. Functional Gene Ontology Annotation and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed that genes coexpressed with IGFBP4 and IGFBP6 were mainly enriched in immune-related pathways. These results were validated using the TIMER and TSMIDB databases. This study demonstrated that the IGFBP family has prognostic value in patients with GBM. IGFBP4 and IGFBP6 are two members of the IGFBP family that had the highest prognostic value; thus, they have the potential to serve as survival predictors and immunotherapeutic targets in GBM.
[Retracted] Computational Insights into the Structural and Functional Impacts of nsSNPs of Bone Morphogenetic Proteins
Authors: Ahmad Hafiz Ishfaq , Ijaz Nabeel , Afzal Gulnaz , Asif Akhtar Rasool , ur Rehman Aziz , Rahman Abdur , Ahmed Irfan , Yousaf Muhammad , Elokil Abdelmotaleb , Muhammad Sayyed Aun , Albogami Sarah M. , Alotaibi Saqer S.
Published: July 2022

BMPs (bone morphogenetic proteins) are multipurpose (transforming growth factor)TGF‐superfamily released cytokines. These glycoproteins, acting as disulfide‐linked homo‐ or heterodimers, are highly potent regulators of bone and cartilage production and repair, cell proliferation throughout embryonic development, and bone homeostasis in the adults. Due to the fact that genetic variation might influence structural functions, this study is aimed to determine the pathogenic effect of nonsynonymous single‐nucleotide polymorphisms (nsSNPs) in BMP genes. The implications of these variations, investigated using computational analysis and molecular models of the mature TGF‐β domain, revealed the impact of modifications on the function of BMP protein. The three‐dimensional (3D) structure analysis was performed on the nsSNP Y316S, V386G, E387G, C389G, and C391G nsSNP in the TGF‐β domain of chicken BMP2 and H344P, S347P, V357A nsSNP in the TGF‐β domain of chicken BMP4 protein that was anticipated to be harmful and of high risk. The ability of the proteins to perform variety of tasks interact with other molecules depends on their tertiary structural composition. The current analysis revealed the four most damaging variants (Y316S, V386G, E387G, C389G, and C391G), highly conserved and functional and are located in the TGF‐beta domain of BMP2 and BMP4. The amino acid substitutions E387G, C389G, and C391G are discovered in the binding region. It was observed that the mutations in the TGF‐beta domain caused significant changes in its structural organization including the substrate binding sites. Current findings will assist future research focused on the role of these variants in BMP function loss and their role in skeletal disorders, and this will possibly help to develop practical strategies for treating bone‐related conditions.
Investigating Temporal Kinematic Differences Caused by Unexpected Stimulation during Gait Termination through the Waveform‐Level Variance Equality Test
Authors: Shen Xi-ang , Cen Xuanzhen , Song Yang
Published: July 2022

The efficacy of the variance equality test in steady‐state gait analysis is well documented; however, temporal information on where differences in variability occur during gait subtasks, especially during gait termination caused by unexpected stimulation, is poorly understood. Therefore, the purpose of the current study was to further verify the efficacy of the waveform‐level variance equality test in gait subtasks by comparing temporal kinematical variability between planned gait termination (PGT) and unplanned gait termination (UGT) caused by unexpected stimulation. Thirty‐two asymptomatic male subjects were recruited to participate in the study. A Vicon motion capture system was utilized to measure lower extremity kinematics during gait termination tasks with and without unexpected stimulation conditions. The F‐statistic for each interval of the temporal kinematic waveform was compared to the critical value using a variance equality test to identify significant differences in the waveform. Comparative tests between two types of gait terminations found that subjects may exhibit greater kinematics variance in most lower limb joints during UGT caused by unexpected stimulation (especially at stimulus delay and reaction phases). Significant greater variances during PGT were exhibited only in the MPJ sagittal and frontal planes at the early stimulus delay phase (4‐15% and 1‐15%). This recorded dataset of temporal kinematic changes caused by unexpected stimuli during gait termination is essential for interpreting lower limb biomechanical function and injury prediction in relation to UGT. Given the complexity of the gait termination task, which involves both internal and external variability, the variance equality test can be used as a valuable method to compare temporal differences in the variability of biomechanical variables.
One-Class Classification by Ensembles of Random Planes (OCCERPs)
Authors: Ahmad Amir
Published: July 2022

One-class classification (OCC) deals with the classification problem in which the training data have data points belonging only to the target class. In this paper, we present a one-class classification algorithm, One-Class Classification by Ensembles of Random Plane (OCCERP), that uses random planes to address OCC problems. OCCERP creates many random planes. There is a pivot point in each random plane. A data point is projected in a random plane and a distance from a pivot point is used to compute the outlier score of the data point. Outlier scores of a point computed using many random planes are combined to get the final outlier score of the point. An extensive comparison of the OCCERP algorithm with state-of-the-art OCC algorithms on several datasets was conducted to show the effectiveness of the proposed approach. The effect of the ensemble size on the performance of the OCCERP algorithm is also studied.
Accurate Recognition of Motion Patterns Based on Artificial Visual Neural Network
Authors: Li Meiqi
Published: July 2022

In order to improve the accuracy of motion pattern recognition, this paper combines the artificial visual neural network to construct a motion pattern recognition system. Moreover, this paper discusses the psychological perception properties of human eyes to color stimuli and gives a description of the observation field of view where the color stimuli are located. At the same time, this paper analyzes the phenomenon of color adaptation and provides a method of color appearance matching through modeling to achieve color appearance matching under variable observation conditions. Based on the chromatic adaptation transformation, a chromatic appearance model is given, which can predict the corresponding color and also predict the chromatic appearance properties of color stimuli under given observation conditions. In addition, this paper constructs an intelligent motion pattern recognition system combined with artificial visual neural network. The experimental results show that the motion pattern recognition system based on artificial visual neural network can accurately identify the motion pattern category.
Compound Ipratropium Bromide plus Budesonide Inhalation in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Its Effect on Heparin-Binding Protein
Authors: Dong Yuan , Li Qingling
Published: July 2022

Objective. To analyze the clinical effect of compound ipratropium bromide combined with budesonide atomization inhalation on acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and its effect on the heparin-binding protein. Methods. A total of 110 patients with AECOPD who were admitted to our hospital between January 2020 and January 2021 were enrolled and assigned into control group (conventional treatment + compound ipratropium bromide) and combined group (conventional treatment + compound ipratropium bromide + budesonide) in a 1 : 1 ratio according to different treatment methods. The clinical effects, pulmonary function indexes, and heparin-binding protein levels before and after treatment were compared between the two groups. Results. The treatment with oxygen-driven nebulization of ipratropium bromide combined with budesonide led to a significantly higher total effective rate versus the treatment with ipratropium bromide alone (P<0.001). After treatment, remarkably higher arterial oxygen partial pressure (PaO2), arterial oxygen saturation (SaO2), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and FEV1/FVC in the combined group vs. the control group were observed (P<0.001). The carbon dioxide partial pressure (PaCO2) levels in the two groups were significantly lower than those before treatment, and the decrease in the combined group was greater (P<0.001). A significantl reduction was observed in heparin-binding protein in both groups after treatment, and the decrease in the combined group was greater versus the control group (P<0.001). Conclusion. Compound ipratropium bromide plus budesonide via aerosol inhalation therapy might be a preferable approach for AECOPD patients. It exhibits a synergistic effect on inhibiting inflammatory mediators and cytokine networks, significantly reduces airway hyperresponsiveness, and improves blood gas indicators and lung function.
Efficacy and Safety of Electroacupuncture for Pain Control in Herpes Zoster: A Systematic Review and Meta-Analysis
Authors: He Kelin , Ni Fengjia , Huang Yi , Zheng Mengyi , Yu Han , Han Dexiong , Ma Ruijie
Published: July 2022

Introduction. Herpes zoster is caused by the reactivation of the latent varicella-zoster virus, which leads to acute pain that may disturb routine activities and affect patients’ quality of life. Electroacupuncture (EA) has been commonly used for treating herpetic pain in clinical treatment. However, no relevant studies have been performed to evaluate the efficacy and safety of EA for acute control in herpetic neuralgia patients. The purpose of the current study was to conduct a systematic review and meta-analysis to address the deficiencies of the current research. Methods. Three English (PubMed, Cochrane Library, and Web of Science) and four Chinese (China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature database (CBM), Wan-fang database, and the Chinese Scientific Journals Full-text Database (VIP)) were comprehensively searched from inception to 31 December 2021. Two independent reviewers evaluated the retrieved data based on the eligibility criteria in advance. In addition, the Cochrane Risk of Bias Tool was used to assess the methodological quality of the included studies. Outcome indexes in this study included the visual analog scale, the time to cessation of pustules, the time to scabs, the time to rash healing, adverse reactions, and the incidence of postherpetic neuralgia. Sensitivity and subgroup analyses were also performed to evaluate the intervention effect specifically. In addition, publication bias was analyzed. Results. Six randomized controlled trials (167 participants in the experimental groups and 174 participants in the control groups) were identified as reporting the application of EA for acute herpes zoster pain and were included in this study. The results from our meta-analysis revealed that EA was superior to control treatment according to visual analog scale, the time of rash healing, and the incidence of postherpetic neuralgia. However, in terms of the time to cessation of pustules, scabs, and adverse reactions, the results showed that EA compared with the control group showed no significant difference. In addition, subgroup analyses indicated that 2/100 Hz-EA has more significant effects on herpetic pain. Sensitivity analyses revealed that the results of EA for acute pain control and the rash healing time in herpetic neuralgia patients were stable. However, a publication bias was observed. Conclusion. Our meta-analysis results showed that EA could offer certain advantages in treating acute pain in herpetic neuralgia patients. However, small sample sizes, heterogeneity in study design, and variable methodological quality weaken these inferences. In addition, weak evidence was found for the safety of EA.
Active Vibration Control of Robot Gear System Based on Adaptive Control Algorithm
Authors: Zhang Dayu , Guan Cong
Published: July 2022

With the aim of solving the errors of gear transmission system in the actual manufacturing process, processing and installation, and solving the the vibration and noise of the gear system caused by the deformation brought about by external excitation such as motor load and actuator, which seriously threaten the safety and stability of unit equipment, a novel active vibration suppression structure of multistage gear system with built-in piezoelectric actuator is designed to generate active control force, and it can be used on the shaft. An active controller is designed and established using FxLMS adaptive algorithm. The results of this method show that by measuring the vibration signal system, the base frequency of the high-speed gear pair is 310 Hz, and the basic frequency of the low-speed gear pair is 192 Hz. I had the adaptation snare go for almost 0.5 seconds, with a difference of 0.52%. Adaptive Trap II reached in 1 second, with a difference of 0.96%. In the active vibration suppression test, the basic frequency of the high-speed gear pair is 804 Hz, and the basic frequency of the low-speed gear connector is 500 Hz. Using the FxLMS adaptive algorithm, it is able to effectively suppress the frequency vibrations of the high-speed dual-gear and low-speed dual-gear coupling systems of multispeed gears. After being controlled by FxLMS algorithm at the second frequency of the high-speed gear, the vibration reduction is about 10 dB at the third frequency of the low-speed gear. The vibration reduction is also approximately 7 dB. This has proved that a new experiment of industrial safety can be used to accelerate the movement of gear vibrations using the FxLMS adaptation algorithm.
Information Steganography Technology of Optical Communication Sensor Network Based on Virtual Reality Technology
Authors: Wang ZhongBao , Li WenMing , Wang GuoQing
Published: July 2022

In order to solve the problems of narrow object orientation and insufficient visual rendering ability of the optical communication network experimental system, the author proposes a multithreaded scheduling using virtual reality, and the experimental system design method of optical communication network with multichannel serial port design is proposed. The system builds the overall structure model of the optical communication network experimental system in the virtual reality environment, and uses the PCI bus technology to build the transmission channel model of the optical communication network, the basic entity object of the optical communication network experimental system is constructed, and the multithread scheduling method is used to process the local information of the experimental system. The result obtained is as follows: The experimental system of optical communication network designed by the author’s method, the optical communication transmission bit error rate is reduced by about 30%, the time overhead is saved by about 60%, and the memory overhead is saved by about 50%, which is superior. Using the author’s method, the maximum bit error rate is about 22%, while the maximum bit error rate of traditional method 1 is about 43%, and the maximum bit error rate of traditional method 2 is about 70%. It is proven that the visual simulation effect of the optical communication network experimental system is good, the reliability and stability of the optical communication network are improved, and the communication transmission error is reduced.
A Case of Common Variable Immunodeficiency with CREBP Gene Mutation without Rubinstein Taybi Syndrome Features
Authors: Musabak Ugur , Ceylaner Serdar , Erdogan Tuba , Ayva Ebru Sebnem
Published: July 2022

Hypogammaglobulinemias, based on inborn errors of immunity, are primary immunodeficiencies (PIDs) that can also be diagnosed for the first time in adulthood. Common variable immunodeficiency (CVID) is a multifactorial disease often symptomatic due to antibody deficiency. In addition, some PIDs are classified into the category of immunodeficiencies with syndromic features due to their accompanying clinical findings unrelated to immunity. In this article, a patient with CVID who was diagnosed in adulthood and who was revealed to have a mutation specific to Rubinstein–Taybi syndrome and clinical features reminiscent of this syndrome only after molecular tests was presented.
Influence of Lower Double-Track Tunnel Spacing on the Stress and Deformation Characteristics of Upper Tunnel in Double-Level Condominium Tunnels
Authors: Zhanjun Huang , Wanglong Guo , Lihong Tong , Xiaohui He , Haibin Ding , Songyan Li
Published: July 2022

The open-cut tunnels in Aixi Lake, Nanchang, are constructed in a condominium form of highway tunnel and subway tunnel, which are the first superimposed double-level tunnels in China. The scientific problems faced by this new structure form have attracted the attention of engineers and researchers. If this structure form can be reasonably used, it can reduce the repeated excavation of the ground and reduce the impact of highway tunnel construction on subway tunnels. It is of great guiding significance to study the influence of the spacing between lower double-track subway tunnels on the stress and deformation characteristics of the upper highway tunnel. Based on the model test, the deformation, axial force, bending moment, and earth pressure of the upper highway tunnel are studied. The results show that the maximum displacement of upper tunnel floor can be reduced by 30% when the spacing of the lower tunnel makes the center line of the lower single tunnel coincide with the quadripartite line of the upper tunnel. Horizontal spacing between lower double-track tunnels significantly influences the bending moment of upper tunnel floor but hardly influences the axial force of the upper tunnel floor. Considering the influence of lower tunnel spacing on the earth pressure of the upper tunnel floor, the spacing of the lower tunnel should not exceed 50% of the section width of the upper tunnel.
Combined Liver Stiffness and Α-fetoprotein Further beyond the Sustained Virologic Response Visit as Predictors of Long-Term Liver-Related Events in Patients with Chronic Hepatitis C
Authors: Chen Sheng-Hung , Lai Hsueh-Chou , Su Wen-Pang , Kao Jung-Ta , Chuang Po-Heng , Hsu Wei-Fan , Wang Hung-Wei , Hsieh Tsung-Lin , Chen Hung-Yao , Peng Cheng-Yuan
Published: July 2022

Aims. Long-term risk stratification using combined liver stiffness (LS) and clinically relevant blood tests acquired at the baseline further beyond the sustained virologic response (SVR) visit for chronic hepatitis C (CHC) has not been thoroughly investigated. This study retrospectively investigated the prognostics of liver-related events (LREs) further beyond the SVR visit. Methods. Cox regression and random forest models identified the key factors, including longitudinal LS and noninvasive test results, that could predict LREs, including hepatocellular carcinoma, during prespecified follow-ups from 2010 to 2021. Kaplan–Meier survival analysis estimated the significance of between-group risk stratification. Results. Of the entire eligible cohort (n = 520) of CHC patients with SVR to antiviral therapy, 28 (5.4%) patients developed post-SVR LREs over a median follow-up period of 6.1 years (interquartile range = 3.5–8.7). The multivariate Cox regression analysis identified two significant predictors of LREs after the year 3 post-SVR (Y3PSVR) baseline (LRE, n = 15 of 28, 53.6%, median follow-up = 4.1 [1.6–6.4] years after Y3PSVR): LS at Y3PSVR (adjusted hazard ratio [aHR] = 3.980, 95% confidence interval [CI] = 2.085–7.597,

P
<
0.001

), and α-fetoprotein (AFP) at Y3PSVR (aHR = 1.017, 95% CI = 1.001–1.034,

P
=
0.034

). LS ≥1.45 m/s and AFP ≥3.00 ng/mL for Y3PSVR yielded positive likelihood ratios of 4.24 and 2.62, respectively. Kaplan–Meier analysis revealed that among the stratified subgroups, the subgroup with concurrent LS ≥1.45 m/s and AFP ≥3.00 ng/mL at Y3PSVR exhibited the highest risk of LREs after Y3PSVR (log-rank

P
<
0.001

). Conclusion. We recommend the combined use of concurrent LS and AFP in future prediction models for LREs in CHC. Patients with concurrently high LS and AFP values further beyond the SVR visit may require a recall policy involving intense surveillance.
Intelligent Recognition of Sports Players’ Wrong Actions in view of Computer Pattern Recognition
Authors: Guo Rui , Qi Bo
Published: July 2022

In the context of the vigorous development of the sports industry and rapid technological innovation, the wrong actions of sports athletes can also be intelligently recognized. Human action recognition based on computer pattern recognition is becoming more and more popular and ubiquitous in life. This article aims to study how to recognize the human body based on the computer model and how to apply intelligent recognition to the wrong actions of sports athletes. The study of the application of intelligent recognition to the wrong actions of sports athletes is of great significance to sports athletes. This article proposes how to intelligently recognize the wrong actions of sports athletes based on computer pattern recognition. In the experiment in this article, wrong sports actions can cause a series of undesirable consequences, such as joint sprains and muscle damage. Among them, the proportion of joint damage caused by wrong actions has reached 24% and has been rising with the increase of the number of experiments and finally reached 35%, which shows that the probability is still very high. After the pull-up adopts intelligent recognition, the error of the pull-up action can be quickly identified and corrected in time, with the correct rate reaching 78%. Therefore, in order to reduce the physical damage caused by sports athletes’ wrong movements, it is necessary to study the intelligent recognition of sports athletes’ wrong movements. The recognition of wrong actions of sports athletes can be carried out through intelligent recognition based on 3D convolutional neural networks, which is of great significance to intelligent recognition.
PKPM Architectural Engineering Software System Based on Architectural BIM Technology
Authors: Fu Ying
Published: July 2022

In order to solve the problems in practical application of Building Information Modeling (BIM) as an innovative tool and production method, the author proposes a method for simulating modern buildings using the Ecotect software. This method establishes a digital BIM parametric model, the digital information technology is directly applied to the whole life cycle of the construction project, and then the effectiveness of the method is verified by examples. The result obtained is as follows: The authors’ method is designed with the assumption that Construct III is below the standard limit throughout the year, in order to meet the requirements of energy-saving design; it is recommended to change the type of external window in the engineering design scheme and make the energy consumption of buildings meet the requirements of energy-saving standards. The method proposed by the author saves about 20% of the construction cost compared with the traditional method. It is proved that the author’s method can make architectural designers correctly understand the feasibility and applicability of the Ecotect software in building energy conservation and promote BIM technology and software; BIM technology can be widely used in engineering projects, allowing architects to select the right and suitable software for various energy conservation simulations and build energy-saving building solutions.
The Impact of Sports Event Branding Using Edge Computing on Urban Marketing under the Background of Internet of Things
Authors: Nie Xiaomei , Qu Yongpeng , Yi Feng
Published: July 2022

The purpose is to explore the impact of sports event branding on urban marketing. Under the Internet of Things (IoT) background, the impact of sports events on the economy and culture of the host city is explored based on the idea of edge computing. In addition, the economic and cultural impact of the current highest level sports event—the Olympic Games—on the host country is also analyzed. The results show that the more large-scale events are held, the more they can promote the development of the high-end market of urban tourism. The hosting of the Beijing Olympic Games brought Beijing $3.127 billion in revenue and great changes in humanities, ecology, living environment, and other aspects. The higher the gross domestic product (GDP) of a domestic city is, the more events will be held in this city, and the two are positively correlated. Domestic competition resources are concentrated in these cities with strong economic strength. The total number of events held by the top 10 cities in GDP accounts for 64.1% of the top 30 cities. Geographically, among the cities that have hosted sports events, there are 89 cities in the east, with a total number of 1676 events, accounting for 64% of the national events, far exceeding the central and western cities, and even far exceeding the sum of the latter two. Therefore, it can be said that the holding of sports events reflects the comprehensive strength of a city and improves the city’s exposure and popularity. The exploration provides a certain reference value for cities to enhance their influence with the help of events.
Somatostatin plus Gastroscopic Administration of Omeprazole for the Treatment of Acute Upper Gastrointestinal Bleeding: An Exploration of a Promising Alternative
Authors: Feng Lu , Fu Jing
Published: July 2022

Objective. To analyze the efficacy and safety of somatostatin combined with gastroscopic administration of omeprazole in the treatment of acute upper gastrointestinal bleeding. Methods. Eligible 112 patients with acute upper gastrointestinal bleeding treated in our hospital from May 2019 to July 2020 were randomized at a ratio of 1 : 1 either to the control group (somatostatin) or observation group (somatostatin combined with omeprazole gastroscope administration). The treatment efficacy, the average hemostasis time, rebleeding rate, average length of hospital stay, and the incidence of adverse reactions were compared. Results. The study group demonstrated significantly higher total effective rate than the control group (96.45% vs. 80.36%, <0.05). The study group demonstrated superior performances compared to the control group with respect to the average hemostasis time ((14.17 ± 2.53 h) vs. (28.84 ± 4.07 h)), rebleeding rate (3.57% vs. 14.28%), and average length of hospital stay ((5.86 ± 1.26 d) vs. (9.74 ± 1.07 d)) (all

p
<
0.05

). The chi-square test revealed a remarkably lower total incidence of adverse reactions in the study group vs. control group which was (4 (7.14%) vs. 12 (21.43%)) (

p
<
0.05

). Conclusion. The combination of somatostatin and gastroscopic administration of omeprazole might be a promising alternative for the treatment of acute upper gastrointestinal bleeding. It improves the clinical treatment effect and controls the symptoms of patients, with a good safety profile.
Optimising the Selection of Input Variables to Increase the Predicting Accuracy of Shear Strength for Deep Beams
Authors: Hameed Mohammed Majeed , Khaleel Faidhalrahman , AlOmar Mohamed Khalid , Mohd Razali Siti Fatin , AlSaadi Mohammed Abdulhakim
Published: July 2022

The deep beam in load transfer is very important as well as difficult to design due to its shear stress problems. Accurate estimation of shear stress would help engineers to get a safer design. One of the major obstacles in building an accurate prediction model is optimising the input variables. Therefore, developing an efficient algorithm to select the optimal input parameters that have the highest information content to represent the target and minimise redundant data is very important. The feature‐section algorithm based on the combination of genetic algorithm and information theory (GAITH) was used to select the most important input combinations and introduce them into the prediction models. Four models were used in this study: locally weighted linear regression (LWLR) based on the radial basis kernel function, multiple linear regression (MLR), extreme learning machine (ELM), and random forest (RF). The study found that all applied models were significantly improved by the presence of the GAITH algorithm, except for the MLR model. The LWLR‐GAITH model showed 29.15% to 47.88% higher performance accuracy in terms of root mean square error (RMSE) than the other hybrid models during the test phase. Moreover, the results of the standard models (without using the GAITH algorithm) proved the superiority of the LWLR model in reducing the RMSE by 34.51%, 55.17%, and 35.35% compared to RF, MLR, and ELM, respectively. Thus, the inclusion of the LWLR model with GAITH has demonstrated a reliable and applicable computer aid for modelling shear strength in deep beams.
Dynamic Characteristics Analysis and Applications of Electromagnetic Environment Based on Group Perception
Authors: Gao Peiwei , Zhi Yongfeng , Hu Chufeng
Published: July 2022

In collectively perceiving an electromagnetic environment, the discrete or statistical method is used to characterize its characteristics. The information received by the sensor is not correlated with each other; therefore, there is no way to obtain the integral dynamic characteristics of an electromagnetic environment. Based on the statistical manifold and the information geometry theory, this paper takes group perception sensors in an electromagnetic space as an associated whole to measure an electromagnetic field in its space. The probability density function of the field distribution measured at any moment is mapped on to a statistical manifold. The “information distance” between the probability density functions of measurement samples at different moments of the statistical manifold is solved to reveal the changes in the whole electromagnetic environment. Simulations are carried out in assumed electromagnetic environments. The simulation results show that when a target enters the electromagnetic space and as its electromagnetic characteristics and positions change, the distribution of “KLD information distances” of its electromagnetic environment changes as well. The method can perceive the RCS of target with −26 dBsm and connect the target with its position information, indicating that the use of the “KLD information distance” distribution can characterize the integral dynamic characteristics of an electromagnetic environment.
Cryptic Marine Diversity in the Northern Arabian Gulf: An Integrative Approach Uncovers a New Species of Oyster (Bivalvia: Ostreidae), Ostrea oleomargarita
Authors: Salvi Daniele , Al-Kandari Manal , Oliver P. Graham , Berrilli Emanuele , Garzia Matteo
Published: July 2022

Animal biodiversity is greatly underestimated in nontemperate marine regions, especially for intertidal benthic organisms such as oysters. Recent surveys in the northern Arabian Gulf suggest the presence of numerous unidentified species, some of which form shallow reef ecosystems while others are cryptic and found under rocks. In this study, we focused on small oysters from Kuwait, which show typical characteristics in common with the genus Ostrea except for the presence of lophine chomata that would link it to the genera Lopha, Dendostrea, and Alectryonella. Phylogenetic analyses based on mitochondrial and nuclear markers unambiguously placed the Kuwait oyster within the Ostreinae as a sister to the Japanese species Ostrea futamiensis. The hypothesis that the Kuwait oyster represents a new species was assessed with phylogenetic and species delimitation methods combined with a morphological assessment. Results corroborated the Kuwait oysters as a new species herein described as Ostrea oleomargarita Oliver, Salvi, and Al-Kandari, sp. nov. The phylogeny of the Ostreinae shows extensive disagreement between morphology-based genera and phylogenetic clades. The genus Ostrea is polyphyletic, and the form and distribution of taxonomic characters such as chomata are not as definitive as suggested in previous studies. This study, along with other recent investigations, confirmed the Arabian Gulf as a key region for discovering marine animal diversity and suggested a possible biogeographic divide between the Eastern and Western Indo-Pacific. A pattern that has been documented in a growing number of taxa and that warrants further research attention.