bluuebunny/crossref_metadata_2025 huggingface dataset:
QUALIDADE DE VIDA DE PACIENTES COM DISTROFIA MUSCULAR DE DUCHENNE: REVISÃO SISTEMÁTICA
Authors: Machado Freitas Mayanna , Conceição Schneider Gabriel , Dos Santos Stefane , Oliveira Santos Andréa Victória , Oliveira de Almeida Luiz Eduardo , Machado Freitas Maysa , De Santana Santos Bruno Felipe , Sena Lopes Lorenna Emília , Da Silva Barroso Sheilla
Published: November 2019

Introdução: A Distrofia Muscular de Duchenne (DMD) é caracterizada por um comprometimento muscular progressivo e irreversível, cujas manifestações clínicas interferem negativamente na qualidade de vida dos pacientes. Objetivo: Realizar uma revisão sistemática sobre a qualidade de vida (QV) dos pacientes com diagnóstico de Distrofia Muscular de Duchenne. Metodologia: Foram consultados artigos publicados entre os anos de 2007 e 2017, utilizando-se Descritores em Ciências da Saúde (DeCS) e Medical Subject Headings (MeSH), através das seguintes bases de dados: SciELO, PubMed e LILACS. Resultados: De um total de 605 artigos, somente 6 atenderam aos critérios de inclusão. Os estudos foram desenvolvidos no Brasil, Estados Unidos, Taiwan, Irã, Alemanha, Itália e Reino Unido. Sete questionários distintos foram utilizados para avaliar a QV em indivíduos com DMD. A incapacidade física foi o domínio mais afetado pelos pacientes e os domínios menos afetados foram a saúde mental e relações interpessoais. Conclusão: Os estudos mostraram bons resultados relacionados à QV, no entanto, muitos deles foram respondidos com ajuda dos cuidadores, o que dificulta o caráter fidedigno dos resultados. Assim, faz-se necessária a realização de mais estudos com escalas de fácil entendimento aos pacientes, de modo a serem obtidas respostas sem a interferência de terceiros.
DESENVOLVIMENTO NEUROPSICOMOTOR E AFETIVO-SOCIAL DE BEBÊS COM FISSURA LABIOPALATINA RELACIONADOS AOS ESTADOS DE HUMOR MATERNO.
Authors: Dos Santos Baldin Mayara , Martins Apolônio Ana Luiza , Ramos Vieira Anaí , Nunes Moretti Cibelle , Merighi Tabaquim Maria De Lourdes
Published: November 2019

O diagnóstico de fissuras labiopalatinas geralmente desencadeia dificuldades no estabelecimento do vínculo mãe-bebê, importante fator para o desenvolvimento infantil pleno. Assim, buscou-se analisar a interferência da depressão e ansiedade maternas no desenvolvimento psicomotor e emocional-afetivo de bebês com fissura labiopalatina. Participaram 40 díades mãe-bebê. Para avaliação da depressão utilizou-se o Inventário de Depressão de Beck (BDI) e para ansiedade, o Inventário de Ansiedade de Beck (BAI).  Na avaliação do desenvolvimento neuropsicomotor (DNPM) dos bebês utilizou-se o Protocolo de Avaliação do Desenvolvimento Global de Crianças no Primeiro ano de Vida e para a retração, a Escala de Avaliação da Reação de Retração Prolongada da Criança Pequena (BADS). Os resultados evidenciaram valores mínimos de depressão (72,5%) e ansiedade (60%). O DNPM apresentou-se dentro da normalidade, 84,7% (DP: 4,39) dos marcos do desenvolvimento infantil. A BADS indicou que 60% das crianças apresentaram boa qualidade afetivo-emocional, 27,5% apresentaram comportamento de risco e 12,5% déficit intenso. Não houve correlação entre nível de depressão materna e o nível de desenvolvimento global do bebê. Houve correlação positiva entre ansiedade materna e a quantidade de gestos de autoestimulação realizada pelo bebê (r=0,40). Conclui-se que o desenvolvimento afetivo-emocional de crianças com fissura labiopalatina não foi afetado pelos níveis de depressão materna, mas o aumento na frequência de gestos de autoestimulação está relacionado a altos níveis de ansiedade materna. O DNPM não foi afetado pelo estado de saúde mental materna, indicando que estar em um ambiente de cuidado institucional pode atuar como um fator de proteção para o desenvolvimento infantil.
Real Work Conditions of Pharmaceutic Servantsat the Beginning of the XX Century (Review)
Authors: Guzev K. S.
Published: November 2019

Introduction. At the beginning of the twentieth century in the pharmaceutical community of Russia there were many problems. On the pages of the special press, such problems as the organization of pharmacy institutions (pharmacies, warehouses, shops, manufactures), directions and prospects for the development of the domestic pharmaceutical industry, its information support, relations within the pharmaceutical community, and the history of the development of world and domestic pharmaceutical science were discussed. However, more and more the subject of discussion was issues related to the fact of the extremely difficult situation of pharmacists-employees.

Text. The paper presents an analysis of the report of B. N. Saltykova «On the need to reduce working hours in pharmacies.» In it, the author presented a detailed and impartial analysis of the activities of pharmacies in the early twentieth century, summarized and formulated claims of pharmacists to government departments, pharmacy owners and the entire pharmaceutical community, substantiating, in particular, the need to reduce the working hours of pharmacy employees.

Conclusion. A detailed study of the contents of the report B. N. Saltykova leads to a clear understanding of the acuteness of issues related to unsatisfactory working and living conditions of pharmacists serving in Russian pharmacies at the turn of the 19th and 20th centuries. To solve this problem and establish normal work and life for pharmacists, a systematic approach is needed, as they would say now. In addition to the 8-hour shift and standardization of duties, changes were required at all levels of pharmaceutical education, changes in the legislative sphere, the search for consensus between the pharmacists-owners and pharmacists-employees, the appropriate labor protection of the pharmacist and the improvement of their life, and, most importantly, changes in society’s attitude to the pharmacist, that is, raising the prestige of this profession.
Investigation of Walnut Herbal Drug Raw Material
Authors: Chebyshev N. V. , Strelyaeva A. V. , Lezhava D. I. , Luferov A. N. , Bobkova N. V. , Kartashova N. V. , Kuznetsov R. M.
Published: November 2019

Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.

Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.

Materials and methods. Chromato-mass spectrometry and TLC were used in the work.

Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.

Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry.
Comparative Characteristics of Determination of Antioxidant Activity of Sea Buckthorn Fruits by Various Methods
Authors: Trineeva O. V.
Published: November 2019

Introduction. Recently, much attention has been paid to the primary assessment of the pharmacological effect of various drugs using in vivo and in vitro tests. It is known that such a medicinal plant as sea buckthorn, in its phytochemical composition is rich in natural antioxidants: carotenoids, tocopherols, flavonoids, ascorbic acid, etc. In some publications there is information about the antioxidant activity of sea buckthorn and fatty oil based on them. However, information on the comparative characteristics of the use of various methods for determining the antioxidant activity of this type of medicinal plant material and the results obtained are not found in the scientific literature.

Aim. The aim of this work was a comparative determination of the antioxidant activity of medicinal plant material of buckthorn fruits of various species of buckthorn.

Materials and methods. The total antioxidant activity of water and water-alcohol extracts from the fruits of sea buckthorn fruits was determined using various techniques recommended in the literature. The antioxidant activity of the extracts was determined by permanganometric titration, in vitro inhibition of adrenaline autooxidation, and also in a biological model, Parametium caudatum cell culture.

Results and discussion. The effect of the extractant polarity on the value of antioxidant activity was studied. It was found that the highest content of antioxidants in the extraction is observed when using 96 % ethanol as an extractant.

Conclusion. Using three methods, the prospects of using sea buckthorn fruits and preparations based on them as a source of antioxidants are shown.
Investigation of the Antiviral Activity of Experimental Samples Obtained from the Grass and Roots of Alchemilla vulgaris L. Against Vaccinia Virus and Ectromelia Virus
Authors: Mazurkova N. A. , Protsenko M. A. , Filippova E. I. , Kukushkina T. A. , Vysochina G. I. , Lobanova I. E. , Mazurkov O. Yu. , Shishkina L. N. , Agafonov A. P.
Published: November 2019

Introduction. The abolition of smallpox vaccination after its elimination in 1980 led to a decrease in the immunocompromised immunity in humans. Zoonotic monkeypox, camelpox, buffalopox and cowpox viruses that are close to the variola virus also pose a danger to humans. In Russia today there are no effective and safe medicines for the prevention and treatment of smallpox and other orthopoxvirus infections in humans and animals. The Lady's mantle (Alchemilla vulgaris) is a promising source for the development of new antiviral drugs. Previous studies have found that Alchemilla vulgaris shows activity against influenza virus and herpes simplex virus.

Aim. The aim of this work was to study the chemical composition and antiviral activity of extracts from the roots and the grass of Alchemilla vulgaris against orthopoxviruses.

Materials and methods. Qualitative analysis of the samples was performed by high performance liquid chromatography. Quantitative analysis was performed using a complex of spectrophotometric methods. To determine the toxicity and antiviral activity of experimental samples from Alchemilla vulgaris in vitro, a transplantable Vero cell culture was used. Antiviral activity of the obtained preparations was evaluated by reducing the infectivity (titer) of orthopoxviruses in the monolayer of Vero cells infected with orthopoxviruses in the presence of preparations with different concentrations relative to the cell culture infected with orthopoxviruses without the preparations.

Results and discussion. It was shown that the experimental sample from Alchemilla vulgaris obtained by the method of ethyl acetate extraction from the roots of the studied plant and purified with chloroform contains mainly catechins and leucoanthocyanins (70 %). In parallel, extract from the raw mass of the grass of the plant purified with chloroform and ethanol contains the amount of flavonoids (71 %). Wherein the content of flavonoids in unpurified ethanol extracts from the roots and the grass of Alchemilla vulgaris composed 5 % and 6 %, respectively. It was revealed that purified preparations obtained from Alchemilla vulgaris roots when using ethyl acetate and ethanol as extractants showed antiviral activity against vaccinia virus and ectromelia virus, as well as preparations obtained from grass by ethanol extraction.

Conclusion. Thus, purified ethyl acetate extracts from the roots and ethanol extracts from the wet grass mass of Alchemilla vulgaris exhibit antiviral activity against orthopoxviruses in vitro.
XVI. YÜZYILDA SAFEVİLER’DE TARİH YAZICILIĞI VE BU DÖNEMDE YAZILMIŞ KRONİKLER
Authors: PEKOL Fatih
Published: November 2019

Safevi Devleti, adını merkezi Erdebil
olan Safeviyye tarikatının piri Şeyh Safiyüddîn Erdebilî’den almıştır. Devletin
kurucusu ise yine bu tarikata mensup olan Şah I. İsmail’dir. Şah İsmail 1501
yılında devletin merkezini Tebriz olarak belirlemiş daha sonra ise Şiiliği
devletin resmi mezhebi olarak seçmiştir. Şah İsmail devleti kurduktan sonra otoritesini
sağlamak için içte birliği sağlamaya çalışmış ve komşu devletlere siyasi ve
askeri üstünlük kurmaya çalışmıştır. XVI. yüzyılda Şah İsmail ve ondan sonra
gelen Şah Tahmasb, Şah II. İsmail, Şah Muhammed Hüdabende ve Şah I. Abbas dönemlerinde
de Safeviler bölgede güçlü bir devlet olarak kalmayı başarmıştır. Çalışmamızın
içeriği de bu şahların hükümranlık sürelerini de kapsayan XVI. yüzyıl Safeviler’de
tarih yazıcılığı anlayışı ve bu dönemde yazılan kroniklerdir.

Çalışma iki bölümden müteşekkil olup birinci
bölümde İran’da İslam sonrası tarihçilik geleneğine ve Safeviler’de
tarihçiliğin oluşum evrelerine değinilmiştir. Bu bağlamda İran’da İslam sonrası
gelişen tarihçilik Arapçanın etkisi altında kalmış, Farsça tarihçilik ise X.
yüzyılda Samanilerden sonra ortaya çıktığı söylenebilir. Safeviler döneminde
tarih yazıcılığı ise XVI. yüzyılda başlamıştır. Ancak gerek devletin yeni
kurulması ve gerekse Şah İsmail’in bazı politikalarından ötürü bu yüzyılın ilk
çeyreğinde tarihçilik fazla gelişim gösterememiştir. Ancak bu süreçlerden sonra
müstakil birçok eser verilmeye başlanmıştır. Çalışmanın ikinci bölümünde ise bu
yüzyılda yazılmış Safevi kronikleri, kronolojik sıraya göre verilmiş olup
eserler müellifleri ile beraber tanıtılmıştır.
MEKANISME PENGISIAN JABATAN KEKOSONGAN JABATAN PRESIDEN DAN WAKIL PRESIDEN; STUDI PERBANDINGAN DENGAN AMERIKA SERIKAT, BRAZIL DAN PERANCIS
Authors: Hariansah Syafri , Erliyana Anna
Published: November 2019

ABSTRAKSatu di antara permasalahan ketatanegaraan yang perlu dikaji secara akademis untuk mendapatkan jawaban akademis adalah permasalahan pengisian jabatan Presiden dan Wakil Presiden di Indonesia. Secara teoritis, pengisian jabatan dapat ditafsirkan dalam2 (dua) perspektif. Pertama dalam artian sempit pengisian jabatan hanya dipahami sebagai suatu proses pengisian jabatan apabilaterjadi kekosongan jabatan Presiden dan Wakil Presiden saja. Kedua, dalam artian luas pengisian jabatan dapat dipahami sebagai suatuproses atau mekanisme yang di dalamnya memuat ketentuan tentang syarat calon, mekanisme pengisian jabatan, masa jabatandan dalam hal terjadi kekosongan jabatan. Penelitian ini mengkaji pengisian jabatan Presiden dan Wakil Presiden di Indonesia dalamartian luas khususnya berkenaan dengan kekosongan jabatanPresiden dan Wakil Presiden. Di Indonesia pengaturan tentang pengisian jabatan Presiden dan Wakil Presiden ini tercantum dalamKetentuan Pasal 6, 6A, 7, dan Pasal 8 Undang-Undang Dasar Tahun1945 serta Undang-Undang RI No. 42 Tahun 2008 tentang Pemilihan Umum Presiden dan Wakil Presiden Republik Indonesia kemudian diganti dan dikompilasikan dalam Undang-Undang No 7Tahun 2017 tentang Pemilihan Umum. Penelitian ini diklasifikasikan sebagai penelitian dengan tipe decriptive explanatory, yakni denganmengumpulkan dan menyimpulkan informasi tentang permasalahan yang diteliti. Sementara studi explanatory digunakan untuk menjelaskan dan menghitung informasi deskriptif. Pendekatan dalam penelitian ini adalah kualitatif. Selain itu untuk memperdalam analisis metode comparative analysis digunakan untuk mendapatkan fokus studi yang khusus dalam masyarakat yang berbeda.Kata kunci : Presiden dan Wakil Presiden, Pengisian jabatan, kekosongan jabatan
UJI AKTIVITAS ANTIBAKTERI SEDIAAN FACE WASH GEL LENDIR BEKICOT (Achatina fulica) DAN KOPI ROBUSTA (Coffea canephora) TERHADAP BAKTERI Staphylococcus aureus
Authors: Utami Novi Fajar , Nurmala Sara , Zaddana Cantika , Rahmah Rizqi Aulia
Published: November 2019

Jerawat adalah masalah yang umum terjadi pada usia remaja dan dewasa karena adanya peradangan dan peningkatan produksi sebum pada kulit, diperparah dengan infeksi bakteri diantaranya Staphylococcus aureus. Penelitian ini bertujuan untuk menentukan formula terbaik sediaan face wash gel dari lendir bekicot dan kopi robusta berdasarkan uji hedonik dan menentukan aktivitas antibakteri sediaan face wash gel terhadap bakteri penyebab jerawat  Staphylococcus aureus dengan kontrol positif sediaan facial wash komersial. Akivitas antibakteri ditentukan dengan menentukan Konsentrasi Hambat Minimum (KHM) menggunakan  metode dilusi padat dan mengukur Lebar Daya Hambat (LDH) menggunakan metode difusi cakram.Dari hasil penelitian diperoleh nilai KHM dari ekstrak kopi berada pada konsentrasi 15%. Konsentrasi tersebut digunakan sebagai acuan pada pembuatan formula sediaan face wash gel dengan tiga perbedaan konsentrasi kopi F1 (5% ), F2 (10%), F3 (15%) dan satu konsentrasi lendir bekicot (12,5%). Berdasarkan hasil uji hedonik, formula 3 merupakan formula yang paling disukai panelis. Pada pengujian terhadap bakteri Staphylococcus aureus formula 3 menunjukkan aktivitas antibakteri tertinggi dengan LDH sebesar 9,160 mm dan memberikan hasil yang tidak berbeda nyata dengan kontrol positif.
UPAYA MENINGKATKAN MINAT BELAJAR SISWA MELALUI PENDEKATAN COLLABORATIVE PROBLEM
Authors: Samosir Benny Sofyan , Lubis Julvian Setiawan
Published: November 2019

Abstrak Penelitian ini dilakukan berlatar belakang rendahnya minat belajar matematika siswa pada SMKMuhammadiyah 13 Sibolga. Guna mengatasi permasalahan itu, peneliti menerapkanpendekatan pembelajaran Collaborative Problem Solving. Yang mana metode ini diharapkanmampu untuk meningkatkan minat belajar siswa kelas X Administrasi Perkantoran, selain itubertujuan untuk meningkatkan aktivitas siswa, kemudian dengan pendekatan ini diharapkandapat meningkatkan kemampuan mengajar guru melalui pendekatan pembelajaranCollaborative Problem Solving dikelas X Administrasi Perkantoran. Type penelitian ini adalahPenelitian Tindakan Kelas. dimana penelitian ini dititik beratkan pada siswa kelas XAdministrasi Perkantoran SMK Muhammadiyah 13 Sibolga dengan jumlah responden 39orang. Sedangkan teknik dan alat pengumpul data yaitu penyebaran angket dan observasi. Hasilpenelitian ini memperlihatkan minat belajar siswa pada siklus I dengan nilai rata-rata 25,33 ataupersentase 50,67% pada siklus II menjadi 34,3 atau persentase 68,7% dengan peningkatansebesar 18,03%. Kadar aktivitas siswa terhadap pelajaran matematika meningkat, hal inidiperoleh dari persentase 60,1% siklus I, dan 88,2% pada siklus II meningkat sebesar 28,1%.Kemampuan guru mengelola pembelajaran persentase sebesar 72% pada siklus I dan 96% padasiklus II, dengan peningkatan sebesar 24%.Kata Kunci: Pendekatan Pembelajaran, Collaborative Problem Solving, Trigonometri.
KEMAMPUAN BERPIKIR KRITIS (CRITICAL THINKING) MAHASISWA SEMESTER 4 (EMPAT) PADA MATA KULIAH PSIKOLINGUISTIK
Authors: Jiwandono Nahnu Robid
Published: November 2019

AbstrakKemampuan berpikir kritis atau critical thinking merupakan salah satu kemampuan yang sangatpenting untuk dikuasai oleh manusia abad 21. Pembelajaran sudah seharusnya diarahkan untukmelatih peserta didik untuk dapat berpikir dengan kritis mengenai suatu masalah. Pembelajaranyang mengajarkan untuk menghafal saja lebih baik mulai diganti dengan menganalisis danmemberikan solusi yang logis. Pada penelitian ini, peneliti berusaha untuk mendapatkan datayang berkaitan dengan hasil tes mahasiswa pada Mata Kuliah Psikolinguistik. Tes yang diujikansudah dipersiapkan sedemikian rupa dengan karakteristik yang beragam, mulai dari soal yangberkategori C1, C2, C3, C4, C5. Hasil penelitian menunjukkan bahwa karakteristikketerampilan berpikir kritis mahasiswa masih kurang. Terbukti dari hasil penelitian didapatkanbahwa soal HOTS (Higher Order Thinking Skills) yang dikerjakan, sebanyak 57% masih salah,sedangkan 43% sudah dijawab dengan benar. Sementara itu, 57% mahasiswa menjawab soalLOTS (Lower Order Thinking Skills) dengan benar dan 43% mahasiswa menjawab salah.Dalam hal ini, peneliti menggunakan sumber data berupa hasil tes yang sudah dirancang olehpeneliti dengan subjek penelitian atau subjek uji adalah mahasiswa semester ke-4 tahun 2018.Kata Kunci: berpikir kritis, HOTS, LOTS
PANDANGAN MAHASISWA PROGRAM STUDI PENDIDIKAN PANCASILA DAN KEWARGANEGARAAN TERHADAP PROFESI PENDIDIK
Authors: Kholidah Neneng Rika Jazilatul , Saputri Ernia Duwi
Published: November 2019

Abstrak Pendidikan merupakan bidang yang sangat penting bagi kehidupan manusia. Pendidikan dapatmendorong peningkatan kualitas manusia dalam dalam bentuk peningkatan kompetensikognitif, afektif, maupun psikomotor.Tujuan dilakukan penelitian ini adalah untuk mengetahuipandangan mahasiswa program studi pendidikan pancasila dan kewarganegaraan terhadapprofesi pendidik. Penelitian ini dirancang sebagai penelitian deskriptif kualitatif dengan strategistudi kasus tunggal terpancang. Sumber data diperoleh dari subyek penelitian sebagai berikut;1) Informan/Narasumber, yaitu mahasiswa Program Studi Pendidikan Pancasila danKewarganegaraan; 2) Aktivitas mahasiswa ketika berdiskusi terkait profesi seorang pendidik.Teknik pengumpulan data yang digunakan adalah wawancara mendalam, observasi secaralangsung dan analisis dokumen. Teknik validitas data menggunakan standar kredibilitas,transferabilitas dan dependibilas dan konfirnabilitas. Teknik analisis data menggunakan metodeinteraktif. Hasil penelitian dapat disimpulkan bahwa Pandangan mahasiswa terhadap profesipendidik adalah Profesi pendidik adalah profesi yang terhormat, Eksistensi profesi pendidik dimasyarkat menurut mahasiswa Pendidik adalah guru masyarakat,Pendidik sebagai peredamkonflik perbedaan budaya dan Profil pendidik ideal menurut mahasiswa dan Alasan mahasiswamemandang profesi pendidik. Guru yang ideal itu tidak mempunyai sifat mementingkan dirisendiri maka guru tersebut bisa dikatakan sebagai guru yang mampu mengerti keinginan anakdidik. Kata kunci: Pandangan, Mahasiswa, Profesi Pendidik
MODELING THE CADASTRAL VALUE OF RESIDENTIAL REAL ESTATE TOMSK
Authors: Lyapunova Anastasia , Kadetova Tatyana
Published: November 2019

Determination of the tax base and the transition to the calculation of the tax, on the property of individuals, based on the cadastral value of residential real estate in the Tomsk region will be carried out from 2020. In this connection, an analysis was made of the residential real estate market in the city of Tomsk, based on the results of which their cadastral value was modeled. Based on the modified cadastral value, the average amount of tax payments for owners of one-, two- and three-room apartments was predicted.
ASSESSMENT OF THE SOCIAL INFRASTRUCTURE OF THE URBAN DEVELOPMENT POTENTIAL USING GIS-ANALYSIS ON THE EXAMPLE OF TOMSK
Authors: Moskovchenko Anastasia , Kozina Mariya
Published: November 2019

This study presents the results of the application of information technology to assess the urban development potential of the territory on the example of the city of Tomsk. A two stages GIS analysis of the territory of a large administrative district of the city of Tomsk was carried out. At the first stage, an assessment was made of the needs of the territory of the Oktyabrsky District for social infrastructure facilities. The second step, based on the results of the assessment, was the procedure for finding a land plot for the construction of a general education institution (school) in the residential quarter. Information systems used to search for a land plot for school construction are described and analyzed. Prospects for the development of a GIS resource were identified, in which data on social infrastructure elements for the entire city of Tomsk and the Tomsk region will be combined in a map format using data from GIS analysis methods.
ABOUT VERTICAL BINDING TO AN ABSOLUTE ZERO WHEN DESCRIBING A REAL ESTATE OBJECT IN A THREE-DIMENSIONAL VIEW IN A REAL ESTATE CADASTRE
Authors: Shayman Nadezhda , Ilyinykh Anastasia
Published: November 2019

The article proposes the revision of the relevant sections of the technical plan, allowing to describe the property in three-dimensional form, taking into account the elevation relative to absolute zero.
THE ISSUE OF TECHNICAL AND CADASTRAL ACCOUNTING OF «GREEN INFRASTRUCTURE» OBJECTS
Authors: Maksimenko Lyubov , Dudinova Olga
Published: November 2019

The article identifies the problems associated with the legal regulation of technical and cadastral accounting of real estate infrastructure based on the analysis of economic activity. The objects of "green infrastructure" and their information support in urban management systems are considered. It is noted that in the process of operation of the "green infrastructure" of great importance is their timely technical accounting and inventory, which, along with the assessment and monitoring, constitute a system of management activities. It is established that technically competent and methodically prepared approach to technical accounting of non-residential facilities, including infrastructure facilities, is their digital certification, conducted on the basis of technical inventory. The studies correspond to the development of urban agglomerations, developed by the standard "Smart Сity".
BASIC DIRECTIONS OF PERFECTION SYSTEM OF STATE CADASTRAL VALUATION
Authors: Gubanischeva Maria
Published: November 2019

The article discusses the main features of the formation the initial data of real estate for the state cadastral valuation. The author's interpretation of the concept of cadastral valuation as a system is proposed and its main constituent elements are given. Methods for collecting, updating and systematizing information on the objects of valuation have been developed. It allows to create the most comprehensive baseline information on the quantitative and qualitative characteristics of real estate and to ensure the effectiveness of cadastral valuation. The necessity of using additional information systems to collect, update and systematize information as a way to increase the level of reliability of the taxable base of real estate objects is substantiated. Including the organization of information interaction of the state budget institution and the rights registration authority is presented.
LAND MANAGEMENT LEGAL MECHANISM AND ITS CRITERION EVALUATION
Authors: Zharnikov Valeriy , Kreymer Mikhail , Stegnienko Elena
Published: November 2019

On the basis of analysis of the definition, structure and use of "legal mechanism" the article determines its systemic features and basic role in legal regulation system, evaluating real possibilities for solving actual problems on real examples. Special focus is placed onto realization of legal mechanism, reflected in related normative acts with the following detalization of the order of achieving the stated objectives on the level of a particular territory, branch, enterprise. The article underlines the role of the legal mechanism realization control system and the achievement of final objectives – the required social and economical results with its help. The result of this research is: the notion of legal mechanism, its structure, special features of its formation; the order of legal mechanism realization in the achievement of the stated objectives, the criteria of which become the final results.
ABOUT TRADITIONS AND INNOVATIONS IN THE DOMESTIC LAND MANAGEMENT AND CADASTRE
Authors: Zharnikov Valeriy , Larionov Yuriy , Pas'ko Ol'ga
Published: November 2019

The development of land management and cadastre historically kept pace with the development of national statehood, which determined their special national character and individual qualities, which later received the status of international traditions: state status, legal significance, obligation and regularity of the update of real estate data, the data use for taxation and territorial administration. The modern period has strengthened the role of cadastre and urban planning, the content of which is aimed at ensuring the equal interests of the state, business, civil society and citizens. Rational consideration of this circumstance, with the development of widespread digitalization, become the main criteria for the development of the discussed knowledge areas and practice.
ANALISIS KEBUTUHAN PENGATURAN BILLING RATE OLEH MENTERI KEUANGAN
Authors: Muliawan Yuliardi
Published: November 2019

Saat ini pengaturan mengenai penyusunan RAB untuk jasa konsultansi telah tersedia baik yang dibuat oleh pemerintah maupun oleh asosiasi jasa profesi  terkait. Namun demikian terdapat temuan BPK terhadap instansi pemerintah daerah dimana dalam penyusunan anggaran untuk satuan biaya billing rate  mengacu pada SEB Kepala BAPPENAS dan Menteri Keuangan nomor 1203/D.II/03/2000 dan SE-38/A/2000 tanggal 17 Maret 2000 tentang Petunjuk penyusunan Rencana Anggaran Biaya (RAB) untuk jasa konsultansi (Biaya Langsung Personil (Remuneration) dan Biaya Langsung Non Personil (Direct Reimbursable Cost)). Menurut rekomendasi pada auditnya, BPK menyarankan agar Billing rate diatur oleh Menkeu melalui PMK Standar Biaya. Selanjutnya, melalui penelitian ini berusaha menjawab secara filosofis dan yuridis melalui telaah literature mengenai perlu atau tidaknya billing rate diatur oleh Menkeu melalui PMK Standar Biaya. Kemudian hasil dari penelitian ini diharapkan dapat menjadi bahan pertimbangan bagi pembuatan kebijakan terkait billing rate.
KAJIAN ATAS IMPLEMENTASI PMK NOMOR 195/PMK.02/2014 TENTANG STANDAR STRUKTUR BIAYA
Authors: Irwanti Lies Kurnia
Published: November 2019

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KAJIAN INDEKSASI
Authors: Irwanti Lies Kurnia
Published: November 2019

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ANALISIS PENGHITUNGAN PROYEKSI BELANJA OPERASIONAL KEMENTERIAN NEGARA DAN LEMBAGA UNTUK PENYUSUNAN PAGU INDIKATIF
Authors: Zamaro Renosa Tosca
Published: November 2019

In Directorate General of Budget, two methods are used in formulating forecast of operational spending in Line Ministries to produce Indicative Budget. The first method uses the realization of line ministries operational spending two years prior to the planned fiscal year as the basis for the forecast. Whereas in the second method, the operational spending allocation is forecasted based on budget allocation in the APBN one year prior to the planned fiscal year. This study aims to find out a better calculation model in operational spending forecasting in line ministries. Two methods used in Directorate General of Budget in forecasting operational spending is analyzed using multiple linear regression using panel data. The analysis conducted on 71 Line Ministies during five years period, 2011 to 2015. The result of the study indicates that the method to forecast operational spending allocation using budget allocation in the APBN one year prior to the planned fiscal year is statistically better.
EFEKTIVITAS KEBIJAKAN STANDAR BIAYA PERJALANAN DINAS DALAM MENUNJANG KINERJA KEMENTERIAN NEGARA/LEMBAGA
Authors: Mahfudin Mahfudin
Published: November 2019

This study aims to examine the effect of cost standard policy on official travel which is reflected in official travel expenditures on the achievement of Ministry/Institution program performance. The study was carried out in the 2016 where the budget for the cost of official travel was be reducted, with a quantitative analysis method, namely correlation analysis and CHAID methods. The results showed that official travel expenditure had a significant relationship and influence on the achievement of Ministry/Institution program performance in 2016, including the achievement of output of program.

Abstrak

Kajian ini bertujuan meneliti pengaruh kebijakan standar biaya perjalanan dinas yang dicerminkan dengan belanja perjalanan dinas terhadap pencapaian kinerja program Kementerian/Lembaga. Kajian dilakukan pada tahun anggaran 2016 dimana pada tahun tersebut telah dilakukan penghematan anggaran biaya perjalanan dinas, dengan metode analisis kuantitatif yaitu menggunakan analisis korelasi dan analisis CHAID.  Hasil penelitian menunjukkan bahwa belanja perjalanan dinasmemiliki hubungan dan pengaruh yang signifikan terhadap pencapaian kinerja program K/L pada tahun 2016, termasuk pencapaian output program.
Special Issue “Advances in Hybrid Rocket Technology and Related Analysis Methodologies”
Authors: Carmicino Carmine
Published: November 2019

Hybrid rockets are chemical propulsion systems that, in the most common configuration, employ a liquid oxidizer (or gaseous in much rarer cases) and a solid fuel; the oxidizer, stored in tanks, is properly injected in the combustion chamber where the solid fuel grain is bonded [...]
The Effect of Arbuscular Mycorrhizal Fungi on Photosystem II of the Host Plant Under Salt Stress: A Meta-Analysis
Authors: Wang Yingnan , Wang Jinghong , Yan Xiufeng , Sun Shengnan , Lin Jixiang
Published: November 2019

As important components of the photosynthetic apparatus, photosystems I (PS I) and II (PS II) are sensitive to salinity. Salt stress can destroy the PS II reaction center, disrupt electron transport from PS II to PS I, and ultimately lead to a decrease in the photosynthetic capacity of the plant. Arbuscular mycorrhizal fungi (AMF) can enhance the photosynthetic capacity of a host plant under salinity stress. However, this specific effect of AMF is not always predictable. Here, we conducted a meta-analysis including 436 independent observations to compare chlorophyll fluorescence parameters in response to AMF inoculation under salt stress. The results showed that AMF inoculation had a positive total impact on photosynthesis in the host plant. Subgroup analysis showed that annual host plants had better performance in terms of photosynthesis after inoculation. The mitigating effects of AMF on the photosynthetic rate (Pn), actual quantum yield of photochemical energy conversion in PS II (ɸPS II), and electron transfer rate (ETR) in C4 species were higher than those in C3 species. Moreover, the photosynthesis performance of monocotyledon species was better than that of dicotyledon species after AMF inoculation. The woody host plants had higher energy utilization by way of an enhanced electron transfer rate to reduce energy dissipation after AMF inoculation. Finally, the mitigating effect of AMF on plants under moderate salinity was stronger than that under high salinity. Among AMF species, Funneliformis mosseae was found to be the most effective in enhancing the photosynthesis performance of plants. For the analyzed dataset, AMF inoculation alleviated the detrimental effects of salinity on photosystem II of the host plant by improving the utilization of photons and photosynthetic electron transport, and also by reducing the susceptibility of photosystem II to photoinhibition.
Radical Scavenging Activity of Puerarin: A Theoretical Study
Authors: Zhou Huakang , Li Xiangzhou , Shang Yaxuan , Chen Kai
Published: November 2019

Puerarin is a C-glycoside of daidzein, one of the major bioactive ingredients isolated from the root of Pueraria lobata, which has a wide spectrum of pharmacological effects. Although puerarin is well-known for its effective antioxidant activity, there is seldom a systematic theoretical study on its radical scavenging activity. Herein, the free radical scavenging ability of puerarin was investigated systematically by density functional theory (DFT) calculations. The reaction activity was compared with daidzein as well. Three reaction pathways: hydrogen atom transfer (HAT), single electron transfer followed by proton transfer (SET-PT), and sequential proton loss electron transfer (SPLET) were discussed and compared by thermodynamic parameters such as bond dissociation enthalpy (BDE), ionization potential (IP), proton dissociation enthalpy (PDE), proton affinity (PA), and electron transfer enthalpy (ETE). The reaction kinetics of puerarin with special radicals •OH and •OOH were also studied. The results obtained may be of great significance for better understanding the relationship between the antioxidant properties and structural design of puerarin, as well as other antioxidants.
Application of Neural Networks to Explore Manufacturing Sales Prediction
Authors: Wang Po-Hsun , Lin Gu-Hong , Wang Yu-Cheng
Published: November 2019

Manufacturing sales prediction is an important measure of national economic development trends. The plastic injection molding machine industry has its own independent R and D energy and mass production technology, with all products sold globally through international brands. However, most previous injection molding machine studies have focused on R and D, production processes, and maintenance, with little consideration of sales activity. With the development and transformation of Industry 4.0 and the impact of the global economy, Taiwan’s injection molding machine industry growth rate has gradually flattened or even declined, with company sales and profits falling below expectations. Therefore, this study collected key indicators for Taiwan’s export economy from 2008 to 2017 to help understand the impact of economic indicators on injection molding sales. We collected 35 indicators, including net entry rate of employees into manufacturing industries, trend indices, manufacturing industry sales volume indices, and customs export values. We used correlation analysis to select variables affecting plastic injection machine sales and artificial neural networks (ANN) were applied to predict injection molding machine sales at each level. Prediction results were verified against the correlation indicators, and seven key external economic factors were identified to predict accurate changes in company annual sales prediction, which will be helpful for effective resource and risk management.
Evaluation of Self-Compacting Concrete Strength with Non-Destructive Tests for Concrete Structures
Authors: Nepomuceno Miguel C. S. , Bernardo Luís F. A.
Published: November 2019

Self-compacting concrete (SCC) shows to have some specificities when compared to normal vibrated concrete (NVC), namely higher cement paste dosage and smaller volume of coarse aggregates. In addition, the maximum size of coarse aggregates is also reduced in SCC to prevent blocking effect. Such specificities are likely to affect the results of non-destructive tests when compared to those obtained in NVC with similar compressive strength and materials. This study evaluates the applicability of some non-destructive tests to estimate the compressive strength of SCC. Selected tests included the ultrasonic pulse velocity test (PUNDIT), the surface hardness test (Schmidt rebound hammer type N), the pull-out test (Lok-test), and the concrete maturity test (COMA-meter). Seven sets of SCC specimens were produced in the laboratory from a single mixture and subjected to standard curing. The tests were applied at different ages, namely: 1, 2, 3, 7, 14, 28, and 94 days. The concrete compressive strength ranged from 45 MPa (at 24 h) to 97 MPa (at 94 days). Correlations were established between the non-destructive test results and the concrete compressive strength. A test variability analysis was performed and the 95% confidence limits for the obtained correlations were computed. The obtained results for SCC showed good correlations between the concrete compressive strength and the non-destructive tests results, although some differences exist when compared to the correlations obtained for NVC.
Identification of Markers in Challenging Conditions for People with Visual Impairment Using Convolutional Neural Network
Authors: Elgendy Mostafa , Guzsvinecz Tibor , Sik-Lanyi Cecilia
Published: November 2019

People with visual impairment face a lot of difficulties in their daily activities. Several researches have been conducted to find smart solutions using mobile devices to help people with visual impairment perform tasks. This paper focuses on using assistive technology to help people with visual impairment in indoor navigation using markers. The essential steps of a typical navigation system are identifying the current location, finding the shortest path to the destination, and navigating safely to the destination using navigation feedback. In this research, the authors proposed a system to help people with visual impairment in indoor navigation using markers. In this system, the authors have re-defined the identification step to a classification problem and used convolutional neural networks to identify markers. The main contributions of this paper are: (1) A system to help people with visual impairment in indoor navigation using markers. (2) Comparing QR codes with Aruco markers to prove that Aruco markers work better. (3) Convolutional neural network has been implemented and simplified to detect the candidate markers in challenging conditions and improve response time. (4) Comparing the proposed model with another model to prove that it gives better accuracy for training and testing.
Autonomous Driving—A Crash Explained in Detail
Authors: Betz Johannes , Heilmeier Alexander , Wischnewski Alexander , Stahl Tim , Lienkamp Markus
Published: November 2019

Since 2017, a research team from the Technical University of Munich has developed a software stack for autonomous driving. The software was used to participate in the Roborace Season Alpha Championship. The championship aims to achieve autonomous race cars competing with different software stacks against each other. In May 2019, during a software test in Modena, Italy, the greatest danger in autonomous driving became reality: A minor change in environmental influences led an extensively tested software to crash into a barrier at speed. Crashes with autonomous vehicles have happened before but a detailed explanation of why software failed and what part of the software was not working correctly is missing in research articles. In this paper we present a general method that can be used to display an autonomous vehicle disengagement to explain in detail what happened. This method is then used to display and explain the crash from Modena. Firstly a brief introduction into the modular software stack that was used in the Modena event, consisting of three individual parts—perception, planning, and control—is given. Furthermore, the circumstances causing the crash are elaborated in detail.By presented and explaining in detail which software part failed and contributed to the crash we can discuss further software improvements. As a result, we present necessary functions that need to be integrated in an autonomous driving software stack to prevent such a vehicle behavior causing a fatal crash. In addition we suggest an enhancement of the current disengagement reports for autonomous driving regarding a detailed explanation of the software part that was causing the disengagement. In the outlook of this paper we present two additional software functions for assessing the tire and control performance of the vehicle to enhance the autonomous.
Role of Obesity, Mesenteric Adipose Tissue, and Adipokines in Inflammatory Bowel Diseases
Authors: Bilski Jan , Mazur-Bialy Agnieszka , Wojcik Dagmara , Surmiak Marcin , Magierowski Marcin , Sliwowski Zbigniew , Pajdo Robert , Kwiecien Slawomir , Danielak Aleksandra , Ptak-Belowska Agata , Brzozowski Thomas
Published: November 2019

Inflammatory bowel diseases (IBDs) are a group of disorders which include ulcerative colitis and Crohn’s disease. Obesity is becoming increasingly more common among patients with inflammatory bowel disease and plays a role in the development and course of the disease. This is especially true in the case of Crohn’s disease. The recent results indicate a special role of visceral adipose tissue and particularly mesenteric adipose tissue, also known as “creeping fat”, in pathomechanism, leading to intestinal inflammation. The involvement of altered adipocyte function and the deregulated production of adipokines, such as leptin and adiponectin, has been suggested in pathogenesis of IBD. In this review, we discuss the epidemiology and pathophysiology of obesity in IBD, the influence of a Western diet on the course of Crohn’s disease and colitis in IBD patients and animal’s models, and the potential role of adipokines in these disorders. Since altered body composition, decrease of skeletal muscle mass, and development of pathologically changed mesenteric white adipose tissue are well-known features of IBD and especially of Crohn’s disease, we discuss the possible crosstalk between adipokines and myokines released from skeletal muscle during exercise with moderate or forced intensity. The emerging role of microbiota and the antioxidative and anti-inflammatory enzymes such as intestinal alkaline phosphatase is also discussed, in order to open new avenues for the therapy against intestinal perturbations associated with IBD.
Phenolic Composition Influences the Health-Promoting Potential of Bee-Pollen
Authors: Mosić Mirjana , Trifković Jelena , Vovk Irena , Gašić Uroš , Tešić Živoslav , Šikoparija Branko , Milojković-Opsenica Dušanka
Published: November 2019

Information on compositional, nutritional and functional properties of bee-pollen, as a health-promoting food, is essential for defining its quality. Concerning the nutritional importance of phenolic compounds, the aim of this study was to determine the phenolic profile and antioxidant activity of twenty-four bee-pollen samples collected from different regions of Serbia. High-performance thin-layer chromatographic (HPTLC) fingerprinting was used for profiling of bee-pollen samples according to the botanical type. HPTLC hyphenated with image analysis and a pattern recognition technique confirmed the grouping of samples caused by the specific phenolic composition of pollens of different botanical origin. Flavonoid glycosides in bee-pollen samples were identified by applying ultra-high-performance liquid chromatography (UHPLC) coupled with linear ion trap-Orbitrap mass spectrometry (LTQ Orbitrap MS). Eight out of twenty-seven flavonol glycosides were identified in bee-pollen samples for the first time. All analyzed bee-pollen samples showed a high number of phenolic compounds which may have therapeutic potential.
Ovarian Cancer—Why Lipids Matter
Authors: Zhao Guangyuan , Cardenas Horacio , Matei Daniela
Published: November 2019

This review highlights recent advances in the understanding of the relevance of altered lipid metabolic pathways contributing to the poor prognosis of high grade serous ovarian cancer, as they relate to cancer metastasis and cancer stemness. Increased lipid uptake regulated by the receptor CD36 and the transport protein FABP4 has been implicated in ovarian cancer metastasis. The symbiotic relationship between ovarian cancer cells and adipocytes was shown to be important for sustaining widespread peritoneal and omental metastasis. Increased lipogenesis dependent on the fatty acid desaturase SCD1 was detected in ovarian cancer stem cells. Furthermore, response to therapy, specifically to platinum, was linked to increased fatty acid biogenesis, while the survival of drug tolerant cells was shown to depend on lipid peroxidation. These recent findings suggest that lipids are necessary elements supporting oncogenic signaling and the energetic needs of rapidly proliferating cancer cells. New strategies targeting key enzymes involved in lipid uptake or utilization in cancer cells have been shown to exert anti-tumor effects and are being developed as cancer interventions in combination with chemotherapy or immunotherapy.