bluuebunny/crossref_metadata_2025 huggingface dataset:
Развитие методик смешанного обучения в контексте цифровых гуманитарных наук
Authors: Гаевская Елена Георгиевна , Борисов Николай Валентинович , Шадиев Рустам Нарзикулович
Published: June 2022

В статье рассматриваются возможности внедрения концепции цифровых гуманитарных наук в практику вуза как предмета области знаний и педагогического метода. Такой подход к обуч
The concept of “ambulatory” and “non-ambulatory” in patients with Duchenne muscular dystrophy: definitions and criteria
Authors: Gremyakova T. A. , Artemyeva S. V. , Vashakmadze N. D. , Vitkovskaya I. P. , Guzeva V. I. , Guzeva O. V. , Kuzenkova L. M. , Mikhailova S. V. , Nazarenko L. P. , Pervunina T. M. , Pechatnikova N. L. , Podkletnova T. V. , Sakbaeva G. E. , Stepanov A. A. , Suslov V. M. , Gremyakova O. I. , Shakhovskaya N. I. , Nikitin S. S.
Published: June 2022

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease due to a mutation in the gene encoding dystrophin synthesis. In patients, muscle damage and atrophy progresses, the ability to move independently decreases as well as respiratory and cardiac functions. At various stages of the disease, different methods of care and treatment of patients with DMD are used. The clinical effect of new methods of DMD target therapy may depend on the stage of development of the disease (ambulatory or non‑ambulatory). To date, there are no unified criteria for assessing the status of a patient in terms ambulatory. In clinical trials and real clinical practice, different approaches are used to assess the patient’s status. However, the conclusion about the functional capabilities is critical for patients with DMD as approaches in management of patients in ambulatory and non‑ambulatory stages differ significantly. This necessitates expert consensus to achieve consistency and avoid any of discrepancies on that issue.

The paper reviews the available published data on the concepts of “ambulatory” and “non‑ambulatory” used in clinical trials, real clinical practice, international standards and recommendations. As a conclusion of this analysis, it is proposed in real clinical practice to interpret “ambulation” in DMD patients as ability to walk without the use of assistive devices and without specifying the distance and time, and “non‑ambulation” as condition in which the patient is forced to constantly use a wheelchair both indoors and outdoors.
Timing of syn-orogenic, high-grade transtensional shear zone formation in the West Uusimaa Complex, Finland
Authors:   University of Leeds, School of Earth and Environment, UK, Torvela Taija , Kurhila Matti ,   Geological Survey of Finland, Espoo
Published: June 2022

We present zircon and titanite U-Pb ages from granulite-facies transtensional shear zones and a greenschist facies strike-slip shear zone in the Karkkila-Vihti area, West Uusimaa. The zircon rim and titanite ages of c. 1815−1820 Ma from the transtensional shear zones constrain the evolution of the orogenic deformation from compression- dominated to syn-compressional lateral-escape within this part of the Fennoscandian shield while the zircon rim and titanite ages of 1790−1800 Ma give the timing of the late- to post-orogenic low-grade reactivation of the large-scale Somero-Karkkila fault zone. The new age data further constrain the timing of the changes in the crustal deformation style during orogenesis from i) compression-dominated to combined transpression - lateral stretching and escape, to ii) the late- to post-orogenic transition into retrograde conditions.
Atraumatic extractions-Indications and treatment modalities
Authors: Kshirsagar Advait Rajesh
Published: June 2022

This paper seeks to enumerate and explain the instruments used commonly for atraumatic extractions, their method of usage and identify their indications. The methodology includes review of journal articles on approaches, benefits and procedures for atraumatic extraction and their compilation. The methodology also includes a review of websites of manufacturers of atraumatic extraction devices and instruments. These sources help to identify the common means for carrying out atraumatic extractions and also the indications for the same. Implants continue to be an exceedingly accepted means to replace an extracted tooth. This may be done immediately following an extraction or at a later date subsequent to satisfactory wound healing. In both situations the need for an atraumatic extraction seems all the more pertinent. Extractions for orthodontic purposes requiring minimal trauma to the surrounding structures of a tooth, particularly the bone, call for a far more atraumatic procedure than the conventional tooth extraction. With the advent of physics forceps, periotomes, luxators piezoelectric instruments and root traction devices atraumatic extractions by preservation of the alveolar bone, the socket, gingival architecture and without trauma to the periodontium has become a necessary skill in the repertoire of the general dental practitioner. This facilitates better implant outcomes or better orthodontic therapy. Newer methods such as Endoscopically Assisted Root Splitting can be used for extractions without causing trauma to the alveolar bone. This can be done using a Storz-Hopkins support endoscope and enlargement of the canals using Lindemann burs followed by longitudinal root splitting and removal using Bein forceps or fragment removal if an implosion technique is used. However, one needs to keep in mind the duration required for such procedure and the cost of instruments required. These methods prevent unnecessary mucoperiosteal flap elevations, incisions and osteotomies thereby minimizing inflammation. To make dental practitioners embrace these procedures, inadequate literature availability and time limitations remain the biggest constraints.
Oral care for patients in intensive care units- A narrative review
Authors: Bhat Sham S , Noorudeen Suhail Abdulla , Bhat Vidya S , Sargod Sharan S , Hegde K Sundeep , Rao H T Ajay , Suvarna Reshma
Published: June 2022

Due to the patient's presenting condition and medical care, maintaining a healthy upper airway in an ICU patient might be difficult. Ventilation-associated pneumonia (VAP) is the most common nosocomial infection in intensive care units (ICUs). The majority of these individuals are unable to execute even the most basic tasks, such as maintaining their own oral hygiene. Oral difficulties may arise as a result of the medical treatment delivered in an Intensive care unit (ICU). Oral care can have an impact on a patient's clinical outcome as well as their overall health. Oral and systemic health, mechanically ventilated patients, barriers to oral health care, published recommendations, and oral care procedure in ventilated patients are all discussed in this article.
Effect of non-surgical periodontal therapy on salivary resistin and chemerin levels in type 2 diabetes mellitus with chronic periodontitis
Authors: Aeran Himanshu , Tuli Amrinder Singh , Chowdhry Rebecca , Mirza Anissa Atif , Kumar Raman , Aulakh Basant Kaur
Published: June 2022

A bidirectional relationship is seen between periodontal disease and diabetes mellitus. Adipokines like resistin and chemerin act as a proinflammatory molecule. Their action is mediated by the generation of pro-inflammatory cytokines and the stimulation of inflammatory cell chemotaxis to the site of inflammation.

This study aimed to compare the levels of resistin and chemerin in saliva in diabetes mellitus type 2 and chronic periodontitis after non-surgical periodontal therapy (NSPT).

Forty-five subjects were recruited and divided into three groups – healthy controls (Group A), chronic periodontitis (Group B) and diabetes mellitus type 2 with chronic periodontitis (Group C). Group B and C received NSPT. The parameters included were gingival index, plaque index, clinical attachment loss and probing pocket depth which were evaluated at baseline and end of three months. Levels of resistin and chemerin in saliva were evaluated using resistin and chemerin enzyme linked immunosorbent assay (ELISA) kit.

At 3 months, PI, GI, PPD and CAL was reduced statistically significant in B and C groups as compared PI and GI of group A. Salivary resistin and chemerin levels were also reduced significantly in all three groups except chemerin in group A. Mean salivary resistin and chemerin levels at baseline were highest in group C followed by group B and least in group A.

Non-surgical periodontal therapy reduces all clinical variables, resistin and chemerin levels. Salivary resistin and chemerin levels can be used as a likely biomarker to assess the outcome following NSPT.
Comparative and qualitative analysis of various decalcifying agents and their affect on staining and texture of the permanent extracted human teeth
Authors: Sharma Jyoti , Sharma Bhagwat Swaroop , Sinha Neel Ratan
Published: June 2022

Teeth are among the hardest human tissues, because they are composed of large amounts of inorganic compounds. Teeth are very difficult to prepare for microscopic examination. Chemical Acids and chelating agents traditionally have been used to remove inorganic contents. We compared various decalcifying agents including strong acids, weak acids, chelating agents. Freshly extracted teeth were fixed and decalcified using formic nitric acid, formic acid, nitric acid, EDTA, trichloracetic acid and Perenyi’s fluid. Decalcified teeth were evaluated histologically for tissue preservation and staining characteristics.

The study aimed at analyzing the rapidity and affects the tissue integrity and staining properties of decalcification of tooth with various decalcifying agents.

60 freshly extracted human teeth were divided into 6 different groups and each was treated with varying concentrations of decalcification solution until they were completely decalcified.

Teeth decalcified with nitric acid solution resulted in rapid decalcification compared to other acids. Teeth treated with EDTA showed very minimal removal of inorganic content over a very long period of time. In routine practice 5% nitric acid can be effectively used for rapid decalcification of teeth in the histopathology laboratory however best staining qualities were noted among the teeth decalcified with formic acid and EDTA.
Evaluation of bond strength of posterior restorative material with tooth treated with silverdiamine fluoride – Invitro study
Authors: Shetty Bhavya , Shetty Shreema , Narayan Nivek
Published: June 2022

Silver diamine fluoride (SDF) solution is being used in arresting dental caries in countries throughout the world since the 1970s. The mechanism of action is that silver-salts promote dentin sclerosis/calcification, silver nitrate has anti-microbial effects, and fluoride helps in the process of remineralization and prevention. The aim of this study is to evaluate the bond strength of posterior restorative material with tooth treated with silver diamine fluoride using universal testing machine

60 premolar tooth were sectioned transversally and each root was embedded in cold-cure epoxy resin. The labial tooth surface was wet ground using silicon carbide discs to prepare a flat superficial dentin. The tooth were conditioned using 10% polyacrylic acid, and divided accordingly. Two increments of resin composite were placed into the plastic tubes of size 5mm X 3mm and each increments were light polymerized for 40 seconds. The same procedure was followed for glass ionomer cement. All specimens were stored at 37 in water for 24hrs before testing. The push out bond strength analysis was tested using the universal testing machine.

The maximum push out bond strength is seen in GIC in dentin-21.85 N/mm, followed by the group with composite-19.27 N/mm and with the lowest value in the group containing SDF+KI+GIC-3.601 N/mm.

Addition of Potassium iodide used to reduce the staining of the SDF does affect the bond strength of the restoration to dentin. GIC has the best bond strength with tooth, followed by composite among the groups.
Knowledge and apprehension score correlation among healthcare workers in COVID-19 block of tertiary care hospital
Authors: Agarwal Anubha , Bhadoria Pooja , Bhati Radhika , Beniwal Sonia , Mishra U B
Published: June 2022

COVID-19 was first detected in Wuhan (China), in December 2019. Mode of transmission was by respiratory droplets)or by surface transmission. Changing symptoms, treatment guidelines, and increased transmissibility of the virus were a concern among the healthcare workers. During the pandemic, the anxiety and stress levels were high among HCWs as they were disturbed by the increased caseload with colleagues testing positive. The present study aimed to find a correlation between knowledge and fear among health care workers working in COVID-19 areas of a tertiary care government hospital.

This was a hospital-based study conducted at a tertiary care hospital, Rishikesh, Uttarakhand. It was an observational study with a cross-sectional study design. The study was conducted in OPD and IPD of COVID-19 for a period of three months. Study participants were consultants, residents, nurses, hospital attendants, and paramedical staff. Pre-structured questionnaires for knowledgeand fear assessment were utilized.

A total of 358 study participants were enrolled. The mean age of study participants was 29± 6.17. The mean knowledge and fear score of all study participants was 9.85 ± 1 and 19.86 ± 5.2 respectively. A negative correlation (r= - 0.04) was found between the knowledge and fear scores. There was a significant difference in knowledge among different groups of HCWs, but the level of fear was not significantly different

It was established that the negative correlation between the knowledge and fear score among health care workers working in COVID-19 situation in tertiary health care hospitalRegular training and dissemination of the new updates regarding the pandemic can help in allaying the fear. Making appropriate personal protective equipment available at the healthcare center will boost the confidence of the health workers.
Evaluation of the efficacy of sodium fluoride varnish, dentine bonding agent and diode laser in the treatment of dentine hypersensitivity: A clinical and scanning electron microscopic study
Authors: Aeran Himanshu , Tuli Amrinder Singh , Paul Supriya Elizabeth
Published: June 2022

One of the most commonly faced clinical problems is dentinal hypersensitivity (DH).It's a "enigma" that's "often met yet seldom comprehended." It is defined as a sensation of discomfort caused by exposed dentine in response to heat, chemical, tactile, or osmotic stimulation. It appears to be a common ailment, with estimates ranging from 4% to 74 percent of the population.

The study aimed in evaluating the efficacy of sodium fluoride varnish, dentine bonding agent and diode laser in treating dentine hypersensitivity in vitro and in vivo.

The research was split into two parts: in vitro and in vivo. In the in vitro study, 40 anterior teeth were extracted and separated into four groups: control, group A (fluoride varnish), group B (dentine bonding agent), and group C (laser), all of which were studied under a scanning electron microscope. For the in vivo part 30 patients aged 20-50 years with the chief complaint of sensitivity to hot and cold were selected from the outpatient department (OPD) of Seema Dental college and Hospital. The patients were divided into 3 groups, group A(fluoride varnish), group B (dentine bonding agent) group C (laser).

At the end of 3 months, there was a statistically significant difference seen in mean VAS and VRS scores between Group A, Group B, and Group C; additionally, the mean of dentinal tubules in the SEM study (In vitro) was seen to be significantly higher in the Control group compared to Group A and Group B, and significantly higher than Group C.

According to the findings of this study, all three treatment methods, sodium fluoride varnish, dentine bonding agent and laser are efficient in reducing dentine hypersensitivity in both in vivo and vitro studies, with laser showing better outcomes.
Prosthetic rehabilitation of a case of post-covid mucormycosis with customized hollow-bulb interim oburator- A case report
Authors: Lalrawngbawli F , Dongre Piyush , Giri Tapan Kumar , Mukherjee Sugata
Published: June 2022

As the on-going battle against COVID-19 continues around the world, India was severly affected during the second wave of the pandemic. Dentists especially Prosthodontists face a special challenge in the aftermath of the pandemic due to the destructive nature of post-covid mucomycosis. There arise a need for the rehabilitation of the maxillofacial structures that have been surgically debrided and removed due to the said fungal infection. The prosthodontist plays an important role in the rehabilitation of such defects with obturators. This paper reports a clinical case of a post-covid Mucormycosis patient with total maxillectomy and fabrication of a customized interim hollow bulb obturator prosthesis.
Two third’s tumour – A case report
Authors: Patel G B Varsha , Siddabasappa Sangeeth , Shetty Ranjani , Ashok L
Published: June 2022

Adenomatoid odontogenic tumour (AOT) is a rare, uncommon, benign odontogenic tumour that constitutes approximately 3% of all odontogenic tumors. It usually occurs in the second or third decade of life with female prediction. AOT commonly occurs in anterior maxilla. An accurate diagnosis should be established through clinical, radiographical and pathological correlations to differentiate AOT from other conditions. In this article we report a case of follicular AOT in 13-year-old female patient with swelling in left maxillary anterior region.
Precious Metals Price Forecast with ARCH Family Models in COVID-19 Pandemic Period
Authors: Oner Hakan , Oner Selma
Published: June 2022

The COVID-19 virus, which was detected for the first time in Wuhan, China in December 2019, spread to all countries of the world and, therefore, became a global epidemic. Although more than two years have passed since the outbreak of the COVID-19 pandemic, the economic effects of it continue. One of these is the effect of the pandemic on precious metal prices. Precious metals, which are called safe harbours and used as investment tools, have had a serious volatility in the last century as a result of the economic, political and pandemic factors changing the international balances. From this point of view, in this study, it is aimed to determine the appropriate forecasting model to predict the volatility of gold, silver, platinum and palladium prices, which are called precious metals, during the COVID-19 pandemic period. The econometric analysis covers the period between March 11, 2020, when the global epidemic was declared by the World Health Organization, and September 13, 2021, and includes 326 days of observation. To determine the appropriate forecasting model, ARCH, GARCH, T-GARCH, E-GARCH and PARCH are used as symmetrical and asymmetrical volatility models.
COVID-19 Disease in Kidney Transplantation Recipients: A Single-Center Study (Experience of Dr. Shariati Hospital)
Authors: Amini Manouchehr , Yaghoubi Seyedeh Fatemeh , Tavakoli Farnaz , Fooladgar Milad , Abdollahpour Esmat , Shahilooy Aidin , Mosayebi Fatemeh , Masoudi Sahar
Published: June 2022

Background: Coronavirus disease 2019 (COVID-19 disease) is caused by SARS-CoV-2. In December 2019, several outbreaks of severe and life-threatening pneumonia with unknown organism were reported in Wuhan, China and the disease spread rapidly all over the world and caused the biggest pandemic. There was no clear information regarding incidence, morbidity, and mortality rate of COVID-19 disease in kidney transplant recipients or other solid organ transplant recipients. Therefore, we designed a study to evaluate the factors that can have any impact on kidney transplant recipients infected with SARS-Cov2.
Methods: Our research was a retrospective cross-sectional study. The study population was all adult kidney transplant recipients (> 18 years old) who were hospitalized due to COVID-19 disease according to national guidelines from 1st March, 2020 to 20th April, 2020 in Shariati Hospital, Tehran, Iran. Demographic data, common clinical complaints, vital signs, types and dose of immunosuppressive drugs, comorbidity diseases, and basic laboratory tests were extracted from the medical records using a data collection form.
Results: According to the results of our investigation, mortality rate was 69.2% in kidney transplant recipients who were admitted in our hospital. No one died under the age of 47 years, while no one survived over the age of 58 years. As a result, age can be a reliable predictor of survival rate in kidney transplant recipients with COVID-19 pneumonia. All patients in non- survivors’ group were elderly and needed intubation, mechanical ventilation, and renal replacement.
Conclusion: In addition to early referral and early start of appropriate and specific treatments of COVID-19 in patients with kidney transplantation, our general advice, is discontinuation of antimetabolite drugs at admission time, dose reduction of calcineurin inhibitors, and even withdrawal of all immunosuppressive drugs except steroids in critical cases.
Explaining Metacognition in Moral Reasoning: A Qualitative Study
Authors: Kamali Farahnaz , Yousefy Alireza , Yamani Nikoo
Published: June 2022

Background: Considerable advances in medical science and modern biotechnology have caused an increasing need for discussing the ethical issues and decision making in the patients. Thus, this is considered as an essential element in medical education. In order to fill this scientific gap, the teachers should be able to investigate the thinking of learners in moral reasoning prior to graduation, thus they can develop the necessary skills in the analysis of clinical situations. This study was designed with an aim to explain the metacognition in moral reasoning in medical departments and based on the Islamic Society of Iran.
Methods: The current study was a qualitative content analysis with a conventional approach where the information was acquired from in-depth personal interviews with 17 clinical professors and students in the medical, nursing, and midwifery majors from Isfahan University of Medical Sciences and Bushehr University of Medical Sciences.
Results: 25 sub-categories, 6 categories, and 3 themes were extracted from the qualitative data. Three themes, including basics of metacognition in moral reasoning, metacognitive process in moral reasoning, and metacognitive responsiveness in moral reasoning, were extracted from the qualitative data. Then, based on the results of the qualitative data, the concept of metacognition was explained in moral reasoning.
Conclusion: Metacognition in moral reasoning in medical departments is a mental process where the medical team uses their knowledge, skills, and experience in observance of the principles and a scientific and reliable process to have the necessary and sufficient responsiveness in their ethical decisions.
Flu Vaccination Fails to Protect Against COVID-19 Infection; A Cross-sectional Study
Authors: Abbasi Mohammad Hossein , Esmaeili Sara , Ansarin Melika , Rimaz Shahnaz , Faiz Seyed Hamid Reza , Riahi Taghi , Aghakhani Kamran
Published: June 2022

Background: Vaccination is likely to be the final solution to stop the COVID-19 pandemic which has been considered as a global public health emergency. Influenza and coronavirus have previously demonstrated antigenic cross-reactivity.
Methods: This cross-sectional study was aimed to evaluate the transmission rate and the severity of coronavirus infection among health care workers with history of previous influenza vaccination. Subjects of the study were asked about their demographics, influenza vaccination history prior to pandemic, infection with COVID-19, and the severity indicators of the disease.
Results: Influenza vaccination has correlation neither with the prevalence of COVID-19 infection rate nor with the severity of the disease process among those who received flu vaccines and those who were not vaccinated. Vaccinated and unvaccinated subjects were equal in terms of sex, age, and comorbidities. Asthma has not been demonstrated to contribute to the severity of the disease.
Conclusion: Influenza vaccination regardless of the evidence on its antigenic cross reactivity with coronavirus, is not associated with lesser involvement by or any contribution to the severity of the 2019 novel SARS-COV2 disease.
Common Data Elements and Features of a Recommender System for People Living with Fatty Liver Disease
Authors: Khademzadeh Samira , Nassiri Toosi Mohsen , Mehraeen Esmaeil , Roshanpoor Arash , Ghazisaeidi Marjan
Published: June 2022

Background: Fatty liver disease is rising as the most common liver disease in recent years. One of the new approaches to manage the disease is the use of intelligent systems. The recommender system is increasingly utilized in managing chronic conditions. This study was performed to identify the common data elements and features of a recommender system for people living with fatty liver.
Methods: This study was a narrative review exploring the minimum data set for a recommender system in fatty liver disease. We aimed to review the current literature evidence to comprehend the specific requirements of the related knowledge. The search was carried out in November 2020 using PubMed, Scopus, Science Direct, and Web of Science databases. We searched the keywords including fatty liver, liver disease, nonalcoholic fatty liver disease, intelligent, smart system, recommender system, minimum data set, data element, and data requirements.
Results: A review of the articles showed that the most common data elements of the administrative category were sex/gender (n=22), age (n=22), and ethnic group/race (n=8). We also identified the clinical data elements and technical features of a recommender system for people living with fatty liver. Based on the findings of this study, “diabetes and glucose status” (n=18), “AST” (n=15), “BMI” (n=13), and “ALT” (n=13) were the most frequent data elements of clinical category. Furthermore, “predicting and identifying” (n=8) was the most common technical feature mentioned in the reviewed articles.‎
Conclusion: We determined the common elements and features of a recommender system in ‎three different categories: clinical data elements, demographic data elements, and technical ‎capabilities. Using these requirements, it is possible to structure data gathering, medication ‎adherence, and communication with healthcare providers in a standard manner. It is ‎suggested that appropriate policies and national grants be adopted to identify and prioritize a ‎minimum data set to support the healthcare services of people living with chronic conditions.
Intravenous Caffeine Infusion Accelerates Emergence from Total Intravenous Anesthesia: A Randomized, Double-blind, Placebo-controlled Study
Authors: Abbasivash Rahman , Aghdashi Mir Mousa , Mahoori Alireza , Hassani Ebrahim , Eghtesaddoust Parisa , Shokohi Shahram
Published: June 2022

Background: Emerging from general anesthesia remains a passive process. Recent studies show the importance of dopaminergic pathways in sleep–wake cycles. The effect of caffeine in increasing the level of consciousness and cognitive function has been well documented. The purpose of the current study was to evaluate the effect of intravenous caffeine, a dopamine receptor stimulant, on accelerating recovery from Total Intravenous Anesthesia (TIVA) with propofol. 
Methods: Fifty patients, aged between 20 to 50 years old scheduled for elective laparoscopic cholecystectomy, were enrolled in this double-blind clinical trial, and forty-eight were analyzed.  The study group, consisting of 24 patients, received 500 mg IV caffeine infusion 15 minutes before the end of the surgery. The control group, comprising 24 patients, received an equal volume of saline infusion.  Emergence profile was evaluated and compared in two groups. The depth of anesthesia was determined by Bispectral Index (BIS) monitoring.
Results: Our research demonstrated that in the study group, the time intervals for increasing BIS values from 60 to 80, endotracheal extubation, eye-opening on verbal command, and achieving an Aldrete’s discharge score ≥ 8 were significantly less than the control group.  Short Orientation Memory Concentration Score (SOMCT) was lower in the control group as well. Incidence of nausea, vomiting and, shivering had no significant difference between the two groups.
Conclusion: Since emergence from general anesthesia is a passive process, caffeine may be used as a measure for active reverse of general anesthesia at clinical practice.
COVID-19 Related Myositis in a Patient Recently Diagnosed with Pre B Cell Acute Lymphoblastic Leukemia
Authors: Aghaghazvini Leila , Torabi Ala , Hasanzadeh Tabatabaei Mahgol Sadat
Published: June 2022

Myositis is not a common finding in patients diagnosed with COVID-19. Up to now, a few cases of COVID-19 associated with myositis have been reported.
A 26-year-old man was referred to the hematology clinic due to leukocytosis and bicytopenia in his lab tests. The patient had no symptoms at the visit session. Following the evaluation, he was hospitalized with the diagnosis of pre-B cell Acute Lymphoblastic Leukemia (ALL) and was considered a chemotherapy regimen consisting of vincristine, methotrexate, cytarabine, and prednisolone. Prior to initiating the treatment, he was diagnosed with COVID-19 with manifestations of fever and dyspnea on the 20th day of hospitalization. The positive Polymerase Chain Reaction (PCR) test confirmed the diagnosis. On the 8th day of COVID-19 related clinical and paraclinical manifestations, the patient was complaining about a vague severe pain in the pelvic region predominantly around his hips. A pelvic MRI was performed to rule out critical etiologies and perimuscular and intramuscular edema was revealed. Creatine Phosphokinase (CPK) and Lactate Dehydrogenase (LDH) were elevated in the lab tests.
His pain was diminished in few days spontaneously and diagnosis of myositis was confirmed.
Myositis can be one of the extra-pulmonary manifestations of COVID-19. Therefore, finding out the association between myositis and COVID-19 can be beneficial for the early diagnosis and prevention of misleading.
Influence of Redesign of the Vessel Hull Structure for Additive Manufacturing on Stability Characteristics
Authors: Dektyarev A.V. , Zobov P.G. , Mulenkova M.V. , Morozov V.N.
Published: June 2022

The article considers the problem of changing vessel stability characteristics due to the optimization of the hull design and the increase in mass due to the choice of polylactide as a hull material for manufacturing by additive technologies. The stability characteristics of a small vessel hull of the "Nerl" kayak type was calculated in two approximations: in the first - for a standard prototype vessel made of fiberglass weighing 35 kg, in the second - for a project under development for additive manufacturing using polylactide weighing 70 kg. Stability was calculated according to the requirements of the Russian River Register using the FreeShip+ and Hydromax software. It was found that not all stability characteristics of the prototype vessel (maximum restoring moment arm) meet the requirements of this register, while for the projected vessel of additive manufacturing all requirements are met. The results of the study may be useful to shipbuilding enterprises planning to organize manufacturing products by 3D printing.
On the Efficiency of Controlling the Compression Ratio of an Internal Combustion Engine
Authors: Agalarov J.H. , Hasanova T.J.
Published: June 2022

The article discusses internal combustion engines with variable compression ratio, which have recently aroused interest. However, the use of such power units is being delayed, because the developed structures include additional joints that limit their power. The article proves the effectiveness of the use of internal combustion engines with an adjustable compression ratio. When calculating and designing an internal combustion engine with spark ignition, much attention is paid to detonation that occurs when it is started, i.e., at high pressure in the cylinder. During subsequent acceleration, the pressure drops, and the engine is under-loaded, which can be compensated by increasing the compression ratio.
Using a Spool Vacuum Pump for Pumping out air with Impurities
Authors: Velikanov N.L. , Naumov V.A.
Published: June 2022

Vacuum pumping systems are widely used in various branches of science and technology. The mathematical model taking into account the hydraulic resistance of the pipeline and the filter of the vacuum pumping system is proposed to study the dynamics of pumping out air with impurities. The dependences of the pumping speed of the spool vacuum pump PKS-016 on the pressure at the pump inlet, the pressure and velocity of gas along the pipeline axis, the mass of argon in the working tank on time are determined. It is shown that in the absence of a mesh filter and a pipeline length of less than 3 m, a simplified mathematical model can be used for the calculation, assuming that the pressures in the working chamber and at the inlet to the spool vacuum pump are equal.
Using the service quality instrument to assess the quality of the professional certification programme
Authors: Firmansyah Firmansyah , Saptono Bambang , Tafakur Tafakur
Published: June 2022

The professional teacher certification programme is a programme that has been implemented online for both in-service teachers and pre-service teachers since 2019. The change in the pattern of implementing the professional teacher programme from offline to online will provide a different programme experience for teachers, participants and tutors. The aim of this research is to measure the quality of service provided to the professional teacher certification programme participants using the SERVQUAL instrument. The instrument used was developed and analysed using confirmatory factor analysis (CFA). Subjects involved were 354 teacher respondents. Data analysis was carried out by SmartPLS version 3. The CFA results show that the model has met the fit index. Convergent and discriminant validity meet the criteria. The CR ranges between 0.948 and 0.989 and CA ranges between 0.917 and 0.985. Finally, the level of service quality provided to the professional teacher certification programme participants at Universitas Negeri Yogyakarta is in the very high level category.

Keywords: Confirmatory factor analysis, service quality, professional teacher certification programme.
Renoprotective Activity of Morinaga Oleifera Lamk Toward Kidney Injury Rats Induced by Streptozotocin
Authors: Gianosa Giovani , Suryono Suryono , Santosa Ali
Published: June 2022

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion. Chronic hyperglycemia in diabetes causes dysfunction and failure of various organs of the body such as the kidneys, eyes, nerves, heart and blood vessels. The purpose of this study was to analyze how the effect of the treatment given by Moringa leaves on diabetes mellitus conditions, especially on glomerular histopathological damage. In this study, to make diabetic mice using the induction of streptozotocin after which Moringa leaves were given as a form of treatment. The dosage of Moringa leaf extract was divided into 5 groups, namely 62.5mg / kg, 125mg / kg, 250mg / kg, 500mg / kg, and 1000mg / kg doses. The histopathological image obtained will be assessed using scoring, and for data analysis using the Kruskal-Wallis test and followed by the post hoc test using the Mann-Whitney test. The results of this study indicate that there is an effect of giving Moringa leaf extract on glomerular histopathological damage. The results of the Kruskal-Wallis data analysis test showed significant results, namely p = 0.001, after the data obtained were significant data, then it was continued with the post hoc test using the Mann-Whitney test with significant results when compared with negative controls ranging from the 125mg / kg dose group 1000mg / kg.
The Experience of Resilience of Chronic Renal Failure Patients with Haemodialysis Therapy: a Qualitative Study
Authors: Ariyani Patricia Yunita Dwi , Istiarini Chatarina Hatri
Published: June 2022

Background: Chronic Kidney Failure patients who have routinely followed haemodialysis therapy have to experience resilience, being able to adapt, survive, and improve their quality of life even though their life is dependent on haemodialysis. Purpose: Objectives to know the experience of the resilience of chronic kidney failure patients with haemodialysis therapy at Hospital, in Yogyakarta Indonesia 2020. Methods: It was qualitative with a phenomenology approach. The sample was 5 people taken with the purposive sampling technique. Data was collected with in-depth interview retrieval via video call with a cell phone as a voice recording device. Content analysis was used with the type of conversation analysis.

Results: The result of the interview obtains 7 themes, namely experience to remain calm, the experience of controlling impulses, having positive expectations, focusing on problems and solving problems, having positive social relationships, belief and trust to achieve problem-solving, and able to achieve positive values in life.

Conclusion: In this research, it shows that the participant response is good. The resilience possessed by five participants is good and in accordance with the source of formation/basic resilience ability, as evidenced by the 7 themes raised. Other researchers are advised to develop this research related to experiences of resilience based on the stages of resilience experienced by patients with chronic kidney failure with haemodialysis therapy.

 

Keywords: Resilience; Chronic Kidney Failure Patients; Haemodialysis (HD)
Why did You do that to Me?: a Systematic Review of Cyberbullying Impact on Mental Health and Suicide Among Adolescents
Authors: Perwitasari Dinar Rizqi , Wuryaningsih Emi Wuri
Published: June 2022

With the new implementation of distance learning, adolescents have more time to access the internet. Lack of surveillance from parental figures and developing senses of mental stability make adolescents susceptible to the negative influence of the internet such as cyberbullying. This systematic literature review aims to examine the incidence of cyberbullying and its effect on the risk of mental health disorders and suicide among adolescents during the COVID-19 pandemic. A total of 10 cross-sectional studies were sorted out from major electronic journal databases: PubMed, Science Direct, BMC, Sage Journal, and Google Scholar using the following search term combinations: “adolescents” “cyberbullying” “suicide” “depression”. The range for adolescents age was 11-18 years. These studies identified and examined general internet use, the experience of cyberbullying, effects on mental health disorder, and risk of suicide published from January 2020 to July 2021. Cyber victimization was positively associated with stress, suicidal ideation, and avoidance which is also a significant predictor of self-harm. Adolescents who experienced cyberbullying were 2-3.14 times more likely to report experiencing suicidal ideations. Suicidal attempts were significantly 2.14 times higher on adolescents who have cyberbullying experience. Previously victimized adolescents have a 15.5% higher chance of being cyberbullied. Internet usage and addiction have direct effects on mediating cyber victimization and adolescents’ psychological symptoms. This study has given broader insight into how cyberbullying can affect mental health in adolescents and identify the gaps for further longitudinal research on cyberbullying among adolescents.
Effectiveness of Cadre Capacity Building Activities: a Comparative Design
Authors: Hayati Nurul , Wahyuningsih Sri , Sulistyono R. Endro , Rahmawati Primasari Mahardika
Published: June 2022

Immunization is a form of health intervention that is very effective in reducing infant and under-five mortality. However, until now the implementation has not reached the maximum target, there are still many people who do not allow their children to be immunized for various reasons. Ignorance of the community or parents about the importance of immunization is one of the main causes, therefore the role of posyandu cadres is needed. One of the roles of posyandu cadres is to provide health education to the community or parents about immunization, so that capacity building activities for cadres are very necessary to increase the knowledge of posyandu cadres. The purpose of this study was to analyze the knowledge and abilities of cadres in an effort to increase the coverage and quality of immunization in Ranupakis Village, Klakah District. The research method was carried out in stages starting from FGD (Focus Group Discussion) activities, pre-test activities to determine the level of knowledge of cadres, health education activities about immunization, and post-test activities. The results of the activity showed that there was a significant influence on the knowledge and abilities of cadres regarding imusization. The conclusion of this study proves that the increased knowledge and ability of cadres has an effect on their role in the coverage and quality of immunization.

 

Keywords: immunization coverage; the role of cadres
Application of Complementary and Alternative Medicine Therapy on Patient with Postoperative Pain After Cardiac Surgery: a Literature Review
Authors: Ariawan I Gede Nova , Raya Nyoman Agus Jagat , Swedarma Kadek Eka
Published: June 2022

Pain is a devastating outcome following cardiac surgery due to routine procedures, including chest tube removal, deep breathing, and coughing exercise. Pharmacological treatment requires complementary interventions in addressing the post-acute pain phase. This study aimed to identify the application of complementary and alternative medicine (CAM) to reduce postoperative pain after cardiac surgery. A literature search was conducted by exploring original studies on the Google Scholar, PubMed NCBI, ProQuest, and ScienceDirect database that published in the last five years (2016-2021), enrolled adult participants who were undergoing cardiac surgery, and evaluated the outcome of CAM therapy on the postoperative pain after the cardiac surgery. Eighteen original studies were analyzed and synthesized. Thirteen studies employed randomized controlled trial, four studies applied quasi-experimental, and one study used one group pre-post-test design. Among these studies, ten studies focused on the manipulative and body-based practices domain (cryotherapy and massage). The application of relaxation exercise, music therapy, and distraction technique from the mind-body intervention domain was discussed in six studies. Only three studies reported the utilization of therapy from the alternative medical system, biologically-based therapy, and energy therapy domain. The majority of the CAM interventions provided significant effects in postoperative pain relief after cardiac surgery. Nurses should be able to assign appropriate CAM therapies for each patient, although all domains of CAM consider as an effective modality for postoperative pain relief after cardiac surgery. Hence, the CAM therapy would be a proper complement for the pharmacological therapies, effective in reducing the pain, and provides a chance for the patient to manage their pain independently.
TIC in postgraduate studies: narratives from teachers about the challenge of performing remote classes
Authors: Vergara Yarelis Karina Araque , Silva Fabrício Oliveira da
Published: June 2022

The article deals with the use of Communication and Information Technologies by graduate professors of a public higher education institution in the state of Bahia. The study aimed to understand how postgraduate professors experienced the challenges of developing remote activities. The research was based on qualitative research, as it excelled in revealing the meanings found in the information, enabling interpretive paths to understand and explore the challenges that postgraduate professors faced to make use of ICT in remote classes. As a device for collecting information, narratives were used, which make it possible to know experiences that teachers produce in a certain context of professional activity. In general, the study made it possible to conclude that teachers have an instrumental skill. In the research, it was possible to identify challenges faced by teachers in remote classes, and how teachers moved to experience new ways of working and new channels of communication.
Student assistance for LGBTQIA+ students: an analysis of institutional policies within the scope of the university residence of a Federal University in Brazil
Authors: Palmeira Lana Lisiêr de Lima
Published: June 2022

The present study aimed to analyze whether, at the Federal University of Alagoas, Campus A.C. Simões, institutional student assistance policies, more specifically referring to the University Residence, capable of ensuring, in a scenario marked by diversity, respect for the values ​​of equity and respect for the human person, in the particular case of students with gender and orientation deviant from heterocisnormativity. As a theoretical-methodological option, this research adopted a qualitative approach, with emphasis on literature review and document analysis. For the analysis of the data found, Bardin's Content Analysis (2016) was chosen. As main results, it was inferred that, although there is a work already started in the mentioned educational institution on the subject in question, it is necessary to adopt more specific actions, defined organically within the university, to ensure greater effectiveness. of the rights of this student audience.
Simulation and Analysis of the Thermal-Mechanical Response of an Energy Pile
Authors: Zhang Peng , Liu Ming , Li Zhengliang , Lv Qihang , Sun Zhongping , Zhang Qingyun , Liu Xiaozheng
Published: June 2022

An energy pile undertakes the functions of supporting the superstructure and controlling the indoor temperature of the building, and the thermal-mechanical coupling response of an energy pile makes its load transfer mechanism different from that of conventional engineering piles. Moreover, the thermal-mechanical coupling responses of the energy piles in summer and winter conditions are also different and need to be explored separately. Based on a ground source heat pump pile foundation workshop project in Kunshan city, Jiangsu Province, a multiphysics simulation study was carried out. The simulation results of the outlet water temperature and pile settlement are consistent with the real-world measurements, which verifies the reliability of the numerical simulation. The responses of the temperature distribution, axial stress, lateral shear stress, and settlement of the energy pile in summer and winter were analyzed, and the response laws of the energy pile in different seasons were obtained. Compared with the pure conventional load state, under the effect of thermal-mechanical coupling in winter conditions, the maximum compressive stress of the pile body is reduced by about 11.5%, but the settlement of the pile top increases by about 47.66%. Therefore, the winter conditions should be used as the design energy for the normal use of the pile. The control condition of the limit state: compared with the pure conventional load state, the maximum compressive stress of the pile increases by about 12% and the settlement of the pile top decreases by about 7.23% under the thermal-mechanical coupling effect of the summer condition. Therefore, the summer condition is the pile control conditions for the limit state of the body’s carrying capacity.