bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling and multiple optimization in face milling of hardfacing welding applied steel: Force, roughness, power
Authors: Günay Mustafa
Published: January 2022

The coating performance for indexable inserts is very important for the main machinability indicators such as energy consumption, cutting force, and surface quality, especially in milling operations. The present study intend to the comprehensive analysis of machining conditions for above mentioned machinability indicators that can be considered most important for sustainability in hard milling of a worn machine part. First, the worn zone of the shearing blade made of X40CrMoV5-1 hot work tool steel was filled with electric arc welding. Then, hard milling experiments were carried out to analyze the performance of different coated carbide inserts in the machining of the hardfacing welded part. Experiments were performed by applying L18 experimental design for invariable cutting depth, three different cutting speed, and feed rate with PVD-AlTiCrN and CVD-TiCN/Al2O3/TiN coated inserts. Machining parameters for the responses namely the resultant force (Fr), surface roughness (Ra), and cutting power (Pc) were simultaneously optimized via applying Taguchi-based grey relationship analysis. Finally, predictive models for the responses were developed by RSM. The results obtained by both coatings shown that the Fr and Ra are mainly influenced by the feed rate, while cutting speed is the parameter that most influenced the Pc. The optimum results with regards to the responses were obtained with the PVD-AlTiCrN coated tool. In the current study, the developed quadratic models and probability graphs indicated that the responses were highly predictable.
COVID-19: Current challenges regarding medical healthcare supplies and their implications on the global additive manufacturing industry
Authors: Goda Ibrahim , Nachtane Mourad , Qureshi Yumna , Benyahia Hamza , Tarfaoui Mostapha
Published: January 2022

The covid-19 outbreak has caused a shortage of masks and other healthcare products for the general public around the globe. In addition, it has also affected the supply of personal protective equipment (PPE) used by healthcare services because of a sudden increase in their demand. This significant disruption in the global supply chain of these products resulted in, leaving many staff and patients without protection. The additive manufacturing (AM) industry is going through extraordinary times and can provide emergency responses to help deal with the global crisis caused by the COVID-19 pandemic. The objective of the present work is therefore to perform an up-to-date review to determine the capacity of AM to provide exclusive benefits for the medical healthcare supplies sector to fight this current situation. In this review, it is found that AM technology has proved that it can be used as a volume manufacturing technology for the ongoing crisis. However, the standardization and certification are appeared to represent the main challenges for adopting the AM in healthcare against COVID-19. Furthermore, additively manufactured materials for medical applications must be developed for medical environments. Most printed medical products for COVID-19 require biocompatibility evaluation and shall prove their ability to sterilize. Finally, this review concluded that AM technology can fulfill the requirements of face masks and ventilator parts for healthcare systems for proper controlling and treating of COVID-19 patients when the safety and efficacy of these devices are ensured.
Dynamic Impacts of Economic Policy Uncertainty on Australian Stock Market: An Intercontinental Evidence
Authors: Bairagi Ranajit Kumar
Published: January 2022

This study empirically investigates the impacts of economic policy uncertainty (EPU) of five countries from four continents on the Australian stock market with monthly observations from January 1998 to January 2021. The dynamic linkage model reports that EPUs are negatively influenced by their own lagged effect along with bidirectional volatility spillover and the returns of stock markets unidirectionally spillover to the EPU of the corresponding economy. The study documents that shocks originated in the Australian stock market spillover negatively onto its own EPU and that of China and positively onto EPUs of Europe and Japan. The shocks originated in EPUs of Australia, Europe, China, and Japan significantly negatively impact the Australian stock market. The bidirectional volatilities of EPUs can offer insight for portfolio investors in searching the possible hedging opportunities in Australia. The reported drivers of Australian EPU can be incorporated in formulating and implementing the EPU-sensitive Australian trade policies.

JEL: G15, G17, G18
Validation of the Palliative Care Nursing Self-Competence Scale for Oncology Nurses in the United States
Authors: Parajuli Jyotsana , Hupcey Judith , Walsh Amanda
Published: January 2022

Oncology nurses care for persons with cancer and thus play an important role in providing palliative care to this population. However, a valid instrument to measure United States oncology nurses’ confidence in providing palliative care service to persons with cancer is not available. This study examined the psychometric properties of the Palliative Care Nursing Self-Competence (PCNSC) scale in measuring oncology nurses’ confidence in providing all aspects of palliative care to persons with cancer. An online survey with demographic questions and the PCNSC scale was sent to registered nurse (RN) members of the Oncology Nursing Society (ONS). The PCNSC scale consists of 50 items and 10 domains. A confirmatory factor analysis (CFA) was conducted to test the psychometric properties of the PCNSC scale in examining oncology nurses’ confidence in providing palliative care. The CFA showed that the model fit reached adequate levels with the 10-factor structure of the PCNSC scale (χ2 = 2104.1, df = 1130, CFI = 0.88, RMSEA = 0.06) thus validating the scale in measuring oncology nurses’ confidence in providing palliative care to persons with cancer in the United States. PCNSC retained the same 10-factor structure with 5 items in each factor, thus validating the scale. This scale can be used to assess oncology nurses’ overall confidence and confidence in each domain of palliative care provision. These results can inform the development of targeted educational programs geared to enhancing oncology nurses’ confidence in the United States.
The Impact of a Franchise Model School Framework on the Leadership Development of Assistant Principals
Authors: Gonzales Miguel M. , Roberts Maria
Published: January 2022

Although the position of the assistant principal is crucial in providing experiences necessary to become an effective school leader, the research on the leadership development of the assistant principal has been largely understudied. This study examines the skills, characteristics, and leadership development of assistant principals within an innovative school structure, “franchise model schools.” This model consists of a successful flagship school principal who is given the charge to simultaneously lead nearby schools while attempting to replicate proven practices, procedures, and structures of the successful flagship school on these added “franchise” schools. Participants of this study included 14 assistant principals, three principals, and the deputy superintendent who oversaw the franchise model schools. Findings revealed three essential characteristics or skills needed by franchise model assistant principals to be successful in their roles: (1) communication of the franchise model vision; (2) collaboration among franchise campuses; and (3) autonomy development. The franchise school model expanded the roles and responsibilities of assistant principals to the level of principal. Assistant principals perceived the model as a more effective way to prepare them for the principalship than traditional methods or career paths. The model provides assistant principals the opportunity to engage in authentic responsibilities of leading a school, possibly decreasing the traditional trajectory of serving as an assistant principal for various years before being considered for a principalship. Because the impact on leadership development is so comprehensive, the “franchise schools” may serve as a model to prepare aspiring school administrators and assistant principals to become principals.
Differential Histone Posttranslational Modifications Induced by DNA Hypomethylating Agents
Authors: Malkaram Sridhar A , Shatnawi Aymen , Fan Jun , Carraway Hetty , Denvir James , Primerano Donald A , Abd Elmageed Zakaria Y , Fandy Tamer E
Published: January 2022

Introduction

The prototype DNA hypomethylating agents 5-azacytidine (5AC) and decitabine (DAC) are currently FDA-approved for treatment of blood and bone marrow disorders like myelodysplastic syndrome. 5AC and DAC are considered similar drugs and were shown to induce histone modifications that modulate gene expression. The aim of this study is to compare the effect of both drugs on histone acetylation and methylation at multiple histone amino acids residues.

Methods

Mass spectrometry was used to compare the effect of both drugs on 95 different histone posttranslational modifications (PTMs) in leukemia cells. ChIP-Seq analysis was used to compare the impact of both drugs on the genome-wide acetylation of the H3K9 mark using primary leukemia cells from six de-identified AML patients.

Results

Both DAC and 5AC induced histone PTMs in different histone isoforms like H1.4, H2A, H3, H3.1, and H4. Changes in both histone methylation and acetylation were observed with both drugs; however, there were distinct differences in the histone modifications induced by the two drugs. Since both drugs were shown to increase the activity of the HDAC SIRT6 previously, we tested the effect of 5AC on the acetylation of H3K9, the physiological substrate SIRT6, using ChIP-Seq analysis and compared it to the previously published DAC-induced changes. Significant H3K9 acetylation changes ( P< .05) were detected at 925 genes after 5AC treatment vs only 182 genes after DAC treatment. Nevertheless, the gene set modified by 5AC was different from that modified by DAC with only ten similar genes modulated by both drugs.

Conclusion

Despite similarity in chemical structure and DNA hypomethylating activity, 5AC and DAC induced widely different histone PTMs and considering them interchangeable should be carefully evaluated. The mechanism of these histone PTM changes is not clear and may involve modulation of the activity or the expression of the enzymes inducing histone PTMs.
Posthumous Autoethnography?
Authors: Badley Graham Francis
Published: January 2022

I play with the idea of my being (nearly) posthumous in contrast to others who demonstrate all the characteristics of being (fully and vibrantly) prehumous. Their forms of collective autoethnography do, however, overlap to an extent with my more modest attempts at sort-of-after-academic-life-writing. Overall, I seek collegiality with those in our world—damaged though it is by our widespread espousal of the pernicious impact of managerialism and neoliberalism—who work for a better, democratic and universal society.
Examination of Home Quarantine Experiences of Individuals Diagnosed With COVID-19 Living in Turkey
Authors: Gök Ayşe
Published: January 2022

The primary purpose of this research is to examine the experiences of individuals diagnosed with COVID-19 regarding the quarantine process. This research was carried out in a phenomenological design, one of the qualitative research approaches. A total of 212 volunteers, 153 women (72.2%) and 59 men (27.8), took part in this research via an online questionnaire. As a data collection tool, an online questionnaire prepared by the researcher was used. The data were analyzed within the framework of content analysis. In the findings of the research, 4 themes named as being diagnosed with COVID-19, quarantine process, worst-case scenario and coping with uncertainty were got. Based on the research findings, in staying in quarantine at home, besides the physiological effects of the virus, it can be concluded that individuals are trying to struggle with the emotional burden of the situation they are in. For this reason, it is of great importance to provide mental health support to individuals who are in quarantine at home, considering the social, psychological, and economic effects of the COVID-19 pandemic.
Early Intensive Behavioral Intervention Program for Children With Autism in Syria
Authors: Mounzer Wissam , Stenhoff Donald M.
Published: January 2022

In this study, we evaluated the effect of the Future Center Early Intensive Behavioral Intervention program on children’s skills longitudinally by sex, age, and diagnoses as dependent variables. Sixty-seven children ages 1–6 years and diagnosed with autism spectrum disorder were followed up for 2 years in Syria. They were assessed twice across the 2-year program: at their first visit and at the end of the program. Assessments included the Autism Behavior Checklist, Childhood Autism Rating Scale, and Adaptive Behavioral Scale–Arabic version. Results showed that the changes in participants’ scores from pre- to post-test were statistically significant, and the treatment group showed significantly larger gains on all scales. No significant differences were found by sex and age between the pre- and post-test on all scales, while there were significant differences regarding diagnoses. The limitations of this study and suggestions for future research are described.
Interactions between language and inhibitory control: Evidence from a combined language switching and Stroop paradigm
Authors: Yahya Mevla , Özkan Ceylan Arzu
Published: January 2022

Aims and objectives:

This study assessed bilinguals’ language control (LC) and inhibitory control (IC) performance (switch costs and Stroop effects) simultaneously in the same participants to investigate how these processes influence each other.

Design:

Seventy-four Turkish-English bilinguals were presented with Turkish (L1) or English (L2) color words printed either in congruent or incongruent ink color and instructed to name the ink color of these words in the presentation language. Stimuli’s language and congruency were either the same as in the previous trial or different.

Data and analysis:

Reaction times (RTs), switch costs (mean RTs on language repetition subtracted from switch trials), and the Stroop effects (mean RTs on congruent subtracted from incongruent trials) were analyzed using the linear mixed-effect model.

Findings:

The switch costs were larger on incongruent than congruent, and the Stroop effects were larger on language switch than repetition trials. This means that the LC performance decreased while resolving conflict, and the IC performance decreased during switching language, indicating that these two share a common IC mechanism. However, the switch costs and Stroop effects across L1 and L2 were symmetrical in all conditions, leaving the previous interpretation uncertain. Besides, the Stroop effects were larger when followed by congruent than incongruent trials during language repetition, whereas they were equal during switching. This means that the ability to adjust performance by previous experience was disrupted during language switching. Moreover, for the high-L2 proficiency group, this ability was diminished in language repetition trials too. These results indicate that rather than inhibition, other processes may primarily mediate bilinguals’ LC.

Originality:

This study provides evidence for how language and inhibitory control influence each other by combining language switching and Stroop paradigms. Furthermore, it investigates the sequential congruency effects (SCE).

Significance/implications:

This study shows that SCE investigation may provide significant theoretical implications.
Display and perception of risk: Analysis of decision support system display and its impact on perceived clinical risk of sepsis-induced health deterioration
Authors: Capan Muge , Schubel Laura C , Pradhan Ishika , Catchpole Ken , Shara Nawar , Arnold Ryan , Schwartz J Sanford , Seagull Jake , Miller Kristen
Published: January 2022

Despite acknowledging the value of clinical decision support systems (CDSS) in identifying risk for sepsis-induced health deterioration in-hospitalized patients, the relationship between display features, decision maker characteristics, and recognition of risk by the clinical decision maker remains an understudied, yet promising, area. The objective of this study is to explore the relationship between CDSS display design and perceived clinical risk of in-hospital mortality associated with sepsis. The study utilized data collected through in-person experimental sessions with 91 physicians from the general medical and surgical floors who were recruited across 12 teaching hospitals within the United States. Results of descriptive and statistical analyses provided evidence supporting the impact of display configuration and clinical case severity on perceived risk associated with in-hospital mortality. Specifically, findings showed that a high level of information (represented by the Predisposition, Infection, Response and Organ dysfunction (PIRO) score) and Figure display (as opposed to Text or baseline) increased awareness to recognizing the risk for in-hospital mortality of hospitalized sepsis patients. A CDSS display that synthesizes the optimal features associated with information level and design elements has the potential to enhance the quantification and communication of clinical risk in complex health conditions beyond sepsis.
‘This Helps You See Life Differently’: Evaluating Youth Development and Capability Expansion in Remote Communities of Honduras
Authors: Wyngaarden Sara , Humphries Sally , Skinner Kelly , Tosta Esmeralda Lobo , Portillo Veronica Zelaya , Orellana Paola , Dodd Warren
Published: January 2022

Youth in rural Honduras experience barriers to accessing education, vocational training, and social supports for their formative development. This study evaluated over 18 years of youth-specific development interventions implemented by a Honduran organization in two rural municipalities. The study draws on 94 semi-structured interviews and demographic data from 1596 program participants. Three impact pathways were identified through which respondents experienced positive outcomes from program involvement: transformative participation; meaningful collaboration; and low-risk experimentation. The findings parallel known development theories and empowerment frameworks, including the Human Development and Capabilities Approach and Positive Youth Development, thus supporting the effectiveness of these approaches in facilitating youth development and capability expansion in remote Honduran communities.
Experimental study on controlled hot surface assisted compression ignition (HSACI) in a naturally aspirated single cylinder gas engine
Authors: Judith Joern Alexander , Kettner Maurice , Koch Thomas , Schwarz Danny , Klaissle Markus
Published: January 2022

Homogeneous charge compression ignition (HCCI) promises low [Formula: see text] emissions and high efficiency due to fast combustion at low temperatures. However, the control of combustion timing represents a serious challenge due to the lack of dedicated ignition control parameters. This challenge is addressed in this work by means of a hot surface ignition (HSI) system, whose core element consists of a shielded, electrically heated ceramic glow plug. In this approach, termed as hot surface assisted compression ignition (HSACI), a small portion of mixture is thought to ignite in the vicinity of the shielded glow plug and to subsequently propagate to the main combustion chamber in order to initiate bulk-gas auto-ignition. Adjusting the hot surface temperature enables to either advance or retard the onset of combustion and thus, allows to control combustion timing. This paper presents experimental results of initial engine trials, using the HSACI concept in a naturally aspirated single cylinder natural gas engine. Measurements were conducted at a constant engine speed of 1400 l/min and include intake air temperatures in the range of 150–175°C and relative air-fuel ratios ([Formula: see text]) from 2.0 to 2.8. Results show that the HSI system enables combustion under conditions, which do not allow for pure HCCI operation. Moreover, the combustion timing can be actively controlled within certain limits by changing the HSI temperature. Increasing cycle-to-cycle variations limit stable operation at lower temperatures, while a transition to pure HCCI is found at intake temperatures beyond 170°C. The applicable [Formula: see text] range is limited by knocking or uncontrolled combustion toward the rich side and instable operation toward the lean side. Loss analysis points out that wall heat flow and imperfect combustion represent the dominant loss mechanisms. Heat release analysis reveals two pronounced phases, indicating initial flame propagation and subsequent auto-ignition similar to spark assisted compression ignition (SACI).
Learning and unlearning: Settler engagements in long-term Indigenous–settler alliances in Canada
Authors: Davis Lynne , Denis Jeffrey S. , Hiller Chris , Lavell-Harvard Dawn
Published: January 2022

Drawing on three cases of long-term Indigenous–settler alliances in Canada, this research investigates the roles and contributions of settlers towards decolonization. As a multidisciplinary team of Indigenous and non-Indigenous scholars, our research goal has been to understand how such alliances endure and change over time, and how they negotiate power dynamics, tensions and changes, within a settler colonial context. Taking a comparative case study approach, and analysing interviews, sharing circles and archival documents, we focus here on the lessons that alliance participants have learned from their activist experiences about settler roles and responsibilities. The three cases include (1) The Right to Belong: Indigenous women’s organizing and the struggle to eliminate sex discrimination in the Indian Act; (2) Shoal Lake 40 First Nation’s Freedom Road campaign to end a century of state-imposed geographic isolation and to secure access to safe drinking water; and (3) the alliance-building and solidarity activism of Canadian ecumenical social justice coalitions now under the umbrella of KAIROS Canada. While none of these campaigns alone equates to decolonization in the sense of land return and Indigenous sovereignty, each has helped create the conditions, relationships and transformations in settler consciousness that may provide the ground for decolonization. Taken together, the three case studies illustrate the contingent environments in which alliances are forged and the ways in which settlers take up particular responsibilities based on Indigenous-defined goals.
Seeing the Bigger Picture: Why Market Research History Matters?
Authors: Crawford Robert
Published: January 2022

Market researchers and the market research industry more generally have paid little attention to the history of market research. This inattention to the past has not only resulted in a significant gap in our knowledge of market research and history more generally, it has also obscured the benefits that can be derived from an understanding of history. Using letters, reports and survey contained in the Ashby Research Service archive at the State Library of New South Wales in Australia, this article seeks to illustrate the benefits to be derived from undertaking historical research on market research and those involved in the market research business. By examining some of the cultural factors informing market research business practices and the ways that the marketing and the media industries have interacted with market researchers, this article not only takes step in addressing the gap in our knowledge of market research history, it also demonstrates the relevance and importance of market research history for business and marketing historians and, indeed, market research scholars and practitioners.
Lighting conditions in physiotherapy centres: A comparative field study
Authors: Zaniboni L , Sarey Khanie M , Pernigotto G , Toftum J , Gasparella A , Olesen BW
Published: January 2022

Visual comfort plays a central role in building occupants’ comfort, well-being and productivity. It is therefore fundamental to meet the occupants’ visual and lighting needs, carefully accounting for the room layout, usage and activities. In this framework, physiotherapy centres constitute a peculiar case since they are occupied by therapists and patients from different age groups, engaged in various activities performed in different positions in the rooms, and affected by different health issues. Lighting quality and satisfaction were monitored in four physiotherapy centres in Northern Italy and Denmark. Subjective assessments were compared with objective illuminance measurements at the task areas, and the sites were also analysed in terms of window and architectural features. Moreover, the interaction between visual and other environmental perceptions was studied. The results revealed: (1) positive influence of daylight access on the satisfaction of occupants; (2) occupants’ complaints about low lighting levels associated with artificial lighting being unable to provide 300 lx and natural light not balancing this lack of illumination; and (3) lower satisfaction among therapists, who also showed the tendency to assess their environmental perception more globally, since correlations between light and daylight satisfaction and other stimuli were observed when comfort issues were present.
Testing lncRNAs signature as clinical stage–related prognostic markers in gastric cancer progression using TCGA database
Authors: Beeraka Narasimha M , Gu Hao , Xue Nannan , Liu Yang , Yu Huiming , Liu Junqi , Chen Kuo , Nikolenko Vladimir N , Fan Ruitai
Published: January 2022

LncRNA expression can be conducive to gastric cancer (GC) prognosis. The objective of this study is to ascertain five specific lncRNAs involved in tumor progression of GC and their role as prognostic markers to diagnose clinical stage-wise GC. High-throughput RNA sequencing data were obtained from The Cancer Genome Atlas (TCGA) database and performed genome-wide lncRNA expression analysis using edgeR package, Bioconductor.org , and R-statistical computing to analyze differentially expressed lncRNA analysis. Cutoff parameters were FDR < 0.05 and |Log2FC| > 2. Total 351 tumor samples with differentially expressed lncRNAs were divided into group-1 lncRNAs such as AC019117.2 and LINC00941, and group-2 lncRNAs such as LINC02410, AC012317.2, and AC141273.1 by 2:1. The Spearman correlation coefficients ( p < 0.05) and correlation test function (cor.test ()) were performed for lncRNAs as per clinical stage. Cytoscape software was used to construct lncRNA–mRNA interaction networks. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway ( p < 0.05) analysis were conducted using the clusterProfiler package. Kaplan–Meier survival analysis was performed to determine the overall survival of patients based on the expression of five lncRNAs in different clinical stages of GC. AC019117.2 and LINC00941 of group 1 inferred a positive correlation with clinical stages of stage I to stage IV, and their expressions were higher in tumor tissues than normal tissues. On the contrary, LINC02410, AC012317.2, and AC141273.1 of group 2 exhibited a negative correlation with clinical stage, and they exhibited more expression in normal tissues compared to tumor tissues. GO and KEGG pathway analysis reported that AC019117.2 may interact with LINC00941 via ITGA3 and trophoblast glycoprotein (TPBG) to foster tumor progression. Tumor-specific group-1 lncRNAs were conducive to the poor overall survival and exhibited a positive correlation with the clinical stages of stage I to stage IV in GC as per the lncRNA–mRNA networking analysis. These five lncRNAs could be considered as clinically useful lncRNA-based prognostic markers to predict clinical stage-wise GC progression.
Identification of a 7-miRNA signature for predicting the prognosis of patients with lung adenocarcinoma
Authors: Liu Ruijun , Guo Zhiyi , Huang Jia , Li Jiantao , Tan Qiang , Luo Qingquan
Published: January 2022

The role of microRNAs (miRNAs) in tumor diagnosis and patients’ prognosis has recently gained extensive research attention. This study was designed to analyze miRNA in lung adenocarcinoma (LUAD) using bioinformatics analysis and to identify novel biomarkers to predict overall survival (OS) for LUAD patients. Differential miRNA expression analysis was performed on LUAD, and normal tissues were extracted from The Cancer Genome Atlas (TCGA). Univariate Cox risk regression and least absolute shrinkage and selection operator (LASSO) Cox analysis were used to screen prognostic miRNAs and develop a risk score model. The prognostic performance of the system was examined utilizing the Kaplan–Meier and receiver operating characteristic (ROC) curves. Independent prognostic factors of LUAD were determined by multivariate Cox regression analysis. Nomogram was constructed according to the independent prognostic factors to evaluate the patients’ one-, three- and five-year OS. A 7-miRNA signature based on miR-584-5p, miR-31-3p, miR-490-3, miR-4661-5p, miR-30e-5p, miR-582-5p, and miR-148a-3p was established. To categorize patients into high- and low-risk groups, the risk score was computed. The OS of the low-risk group was significantly longer than the high-risk group, and the signature showed high sensitivity and specificity in anticipating the one-, three- and five-year OS. The system was an independent factor in predicting the OS of LUAD patients and performed better when combined with the N stage in nomogram. A 7-miRNA signature developed in this study could accurately predict LUAD survival.
Treatment of proximal scaphoid waist nonunions with vascularized bone graft from the distal radius or medial femoral condyle
Authors: Polat Oktay , Toy Serdar , Kibar Birkan
Published: January 2022

Fractures of the proximal scaphoid waist are more prone to nonunion than distal scaphoid fractures. Thirty-nine patients (five females, 34 males; mean age 31 years) who had operation for proximal scaphoid waist nonunion between 2017 and 2020 were retrospectively analysed. Patients received a free vascularized medial femoral condyle graft (Group 1: 18 patients) or distal radial bone graft based on a 1,2 intercompartmental supraretinacular artery pedicle (Group 2: 21 patients). In Group 1, union was achieved in 17 of 18 cases, with mean time to union of 13 weeks and mean operation time was 221 minutes. In Group 2, union was achieved in 19 of 21 cases, with mean time to union of 15 weeks and mean operation time was 100 minutes. The radiological and functional results of both groups were similar. We recommend a distal radial bone graft based on the 1,2 intercompartmental supraretinacular artery pedicle for proximal scaphoid waist nonunions since the operation is shorter, technically more manageable and requires less microsurgical experience.

Level of evidence: III
Fleeting neutrality: The inadequacies of the ex-ante net neutrality regulations in India
Authors: Seth Raghuvansh
Published: January 2022

The paper seeks to address the economic and fundamental inadequacies of ex-ante net neutrality regulations in India. The current net neutrality regulations consider the internet service provider (ISP) market in a two-sided spectrum of content and application providers (CAPs) and end-users. However, the rapidly growing internet space has undergone numerous developments in recent years, giving rise to complexities such as vertical partnerships between the ISPs, CAPs and OTT service providers, the use of content delivery networks (CDNs) for the last mile, deployment of 5G on mobile devices, etc. The main hypothesis is that the ex-ante net neutrality regulations lack the tools to combat modern problems with their antiquated approach and measures. Accordingly, to analyse this proposition, the paper considers the existent literature on the fundamental aspects of net neutrality norms, and juxtaposes the economic and empirical findings from a post‐net neutrality regulation stance. The findings reveal that net neutrality measures that prohibit paid-prioritisation and zero-rating services lead to economic inefficiencies. Further, the restrictive net neutrality measures hamper investment and innovation in the market and fall short in dealing with vertical integration and the use of CDNs. Hence, to promote competition and protect net neutrality, especially in the lower layers of the ISP market, the paper recommends measures such as digital dynamism and transparency rules and studies the role of ex-post competition regulations in aiding net neutrality.
Humor and Personality: Temperament and Character Have Different Roles
Authors: Moreira Paulo A. S. , Inman Richard A. , Cloninger C. Robert
Published: January 2022

This study aimed to test how sense of humor is dependent on the complex and dynamic interactions between the emotional (temperament) and sociocognitive (character) components of personality. Specifically, we examined the relationship of temperament and/or character profiles to overall humor potential and comic style. In total, 665 adults responded to Cloninger’s Temperament and Character Inventory (TCI) and the Comic Style Markers. Temperament profiles were associated with overall humor potential but not comic styles. People with positive development of all three character traits had the highest levels of fun, benevolent humor, and wit. Sense of humor depended on integrated profiles of both temperament and character. We conclude that temperament energizes overall humor potential while character shapes the comic styles. This study advances research by directing focus to the causal within-person psychobiological processes that underlie sense of humor.
Comparison of a Focused Family Cancer History Questionnaire to Family History Documentation in the Electronic Medical Record
Authors: Clift Kristin , Macklin-Mantia Sarah , Barnhorst Margaret , Millares Lindsey , King Zacharay , Agarwal Anjali , Presutti Richard John
Published: January 2022

Introduction:

Family health history can be a valuable indicator of risk to develop certain cancers. Unfortunately, patient self-reported family history often contains inaccuracies, which might change recommendations for cancer screening. We endeavored to understand the difference between a patient’s self-reported family history and their electronic medical record (EMR) family history. One aim of this study was to determine if family history information contained in the EMR differs from patient-reported family history collected using a focused questionnaire.

Methods:

We created the Hereditary Cancer Questionnaire (HCQ) based on current guidelines and distributed to 314 patients in the Department of Family Medicine waiting room June 20 to August 1, 2018. The survey queried patients about specific cancers within their biological family to assess their risk of an inherited cancer syndrome. We used the questionnaire responses as a baseline when comparing family histories in the medical record.

Results:

Agreement between the EMR and the questionnaire data decreased as the patients’ risk for familial cancer increased. Meaning that the more significant a patient’s family cancer history, the less likely it was to be recorded accurately and consistently in the EMR. Patients with low-risk levels, or fewer instances of cancer in the family, had more consistencies between the EMR and the questionnaire.

Conclusions:

Given that physicians often make recommendations on incomplete information that is in the EMR, patients might not receive individualized preventive care based on a more complete family cancer history. This is especially true for individuals with more complicated and significant family history of cancer. An improved method of collecting family history, including increasing patient engagement, may help to decrease this disparity.
From the “Magna Carta” to “Dying in the Streets”: Media Framings of Mental Health Law in California
Authors: Barnard Alex V.
Published: January 2022

This article analyzes 575 newspaper articles across 53 years of reporting on California’s landmark 1967 Lanterman-Petris-Short (LPS) Act to examine framings of the challenges people with severe mental illness pose to the social order and shifting responses to them. The LPS Act restricted involuntary hospitalization which in the 1960s made it a “Magna Carta” that heralded a “mental health revolution” of voluntary, community-based care. Subsequently, coverage passed between four other framings that linked together different attributions of problems—like homelessness or suicide—with perceived flaws of the Act—such as encouraging the closure of hospitals or imposing barriers to forced treatment. Although previous research has focused on how the media amplifies fears of violence, this article shows how this framing is giving way to one focused on mentally ill people “dying in the streets” and the need for re-institutionalization to save them. By comparing media representations with other documentation from each period, this article demonstrates how these frames have continuously misattributed the consequences of complex policy and social changes to the granting of civil rights by the LPS Act.
Factors Affecting the Adoption of Social Media in Marketing of Higher Education: An Empirical Analysis
Authors: John Surej P , Walford Richard , Purayidathil Joseph
Published: January 2022

This study examines the persuasion process involved in social media marketing (SMM), particularly in the higher education sector. Based on the theoretical foundations of the information adoption model, a conceptual model of elaboration of SMM communication is developed and tested. The self-administered survey conducted among a sample of international student travellers in New Zealand examines the influence of argument quality, source credibility, audience involvement and audience engagement on their attitude formation and decision-making. The study particularly examines the mediating effects of audience involvement and engagement in SMM communication. Results based on structural equation modelling suggest that social media content quality is a significant predictor of online users’ transportation, identification and parasocial interaction effects. Despite there being additional evidence to support the arguments over social media, source credibility is found to be a strong influencer of international student traveller’s cognitive, emotional and behavioural engagement dimensions. Further, it is evident from the study that there is a strong correlation between cognitive engagement and attitude formation in SMM. Implications for tourism marketers in terms of SMM strategies are discussed.
Comparison of Frequency of Home Births in the Member States of the EU Between 2015 and 2019
Authors: Galková Gabriela , Böhm Pavel , Hon Zdeněk , Heřman Tomáš , Doubrava Radan , Navrátil Leoš
Published: January 2022

Introduction. The disagreement of the general public’s views on home births is practically identical for the professional public and specialists also. The core of the problem lies in the disunity between individual countries of the European Union—complete prohibition under the risk of committing a crime on one side and standard procedure perceived as something completely common on the other side. Methods. The authors focused on the prevalence of home births in individual EU countries, together with the proportion of neonatological mortality compared to the number of live births, which are data that, unlike home births, are mandatory in each EU Member State. Data on home births were obtained from available official and verified sources such as the Ministry of Health, reviews published by the WHO, or published peer-reviewed scientific and professional works. Secondary data were procured via Web of Science, Scopus, or PubMed. Results. The aim of the study was to trace the documented numbers of home births in the individual states of the European Union in the years 2015 to 2019, to analyze them with data on live births together and with data on infant mortality. A comparative analysis of the compiled data can be used to conclude which countries have the highest domestic birth rates and how the birth rate is manifested in these countries. Based on the analysis of available data, it can be determined that the Netherlands, Denmark, and Germany have the highest share of domestic births. The link between home births and increased neonatal mortality has not been established. Eastern Europe countries have the highest neonatal mortality, namely Romania (1.19%) and Malta (0.63%). Conclusion. The Netherlands has the highest domestic birth rate per 100 000 inhabitants with a 5-year average of 161 922 (overall average of all live births 993.40), but is also in 11th place in neonatal mortality, together with Denmark and Belgium, which have 0.35% neonatal neonatal mortality. The country with the lowest neonatal mortality of 0.19% is Slovenia. The total average of all children born in 5 years (915 live births) is 1.422. When monitoring the number of domestic births in other countries in the years 2015 to 2019, an increasing tendency of this trend is observed.
Service-Learning and the Development of Interpersonal Skills in Pre-Professional Undergraduate Students
Authors: Leonard Gemma , Lassiter Jill W. , Hammill Robert , LeCrom Carrie W.
Published: January 2022

Students who participate in service-learning courses are given the opportunity to apply the knowledge they develop in the classroom to real-world settings while meeting community needs. This study explores how service-learning pedagogy contributes to interpersonal professional skill development in pre-health undergraduate students attending a small, liberal arts college in the mid-Atlantic region of the United States. Students were enrolled in a required course within the health and exercise science department and were pursuing health-related careers. They partnered with local organizations where they engaged marginalized community members in physically active games and programs to promote health. Students then participated in reflective assignments that were qualitatively analyzed. In total, 103 essays and 10 focus groups were coded and interpreted. Three themes emerged as pre-health professional skills developed through the course: communication, perspective taking, and motivating others. Students indicated that service-learning experiences helped them improve in these areas or brought awareness to their struggles with these skills. This study describes how service-learning pedagogy can be used to expand the interpersonal skills of undergraduate students necessary to promote health in all related professions.
Unsettled Employment, Reshuffled Priorities? Career Prioritization among College-Educated Workers Facing Employment Instability during COVID-19
Authors: Cech Erin A. , Hiltner Sofia
Published: January 2022

Millions of workers experienced job instability during the COVID-19 (coronavirus disease 2019) pandemic. A prevailing assumption is that such experiences of instability intensify economic rationality in workers’ career decision making as a matter of course. In contrast, the authors argue that pandemic-related employment instability may have “unsettled” workers’ lives in ways that elevated nonfinancial priorities such as meaningful work. Using proportionally representative survey data ( n = 1,628), the authors compare the priorities of U.S. college-educated workers who were laid off or furloughed during the pandemic with those of workers whose jobs remained stable. Counter to expectations of heightened economic rationality, job-unstable workers were not more likely than job-stable workers to emphasize job security or salary in beliefs about good work. But they were more likely to prioritize passion for work. These findings challenge common assumptions about job prioritization in the wake of crisis-related job instability and have implications for how scholars and policy makers interpret labor force trends.
Uncovering spatial heterogeneity in real estate prices via combined hierarchical linear model and geographically weighted regression
Authors: Hu Yigong , Lu Binbin , Ge Yong , Dong Guanpeng
Published: January 2022

Spatial heterogeneity is important for exploring data relationships between real estate price and its influential factors. The geographically weighted regression (GWR) technique has been frequently adopted for this purpose. In this study, we collected a second-hand real estate house price data set of Wuhan, in which each property is located the same as the community it belongs to. Thus, this data set possesses a typical characteristic, that is, dozens or even hundreds of observations could be allocated to one pair of coordinates, but vary in their attributes. This specific feature might lead to serious problems with bandwidth optimisations and coefficient estimates for calibrating the GWR model. We then proposed an extension by combining the hierarchical linear model (HLM) and GWR, namely HLM-GWR to cope with these problems. Results show that the HLM-GWR performs much better than the conventional GWR and HLM technique in terms of bandwidth optimisation, coefficient estimates. With a controlled simulation test, we again validated the advantage of the HLM-GWR model in comparison to both the HLM and GWR in handling this specific scenario. Overall, HLM-GWR is workable and should be recommended in this case or other scenarios with observations of similar spatial distributions.
Correction of the Hindfoot Alignment after Supramalleolar Osteomy in Ankle Varus Deformity - A Three-Dimensional Analysis Using Weightbearing CT
Authors: Burssens Arne , Kvarda Peter , Steiner Caspar S. , Susdorf Roman , Peterhans Ursina , Krahenbuhl Nicola , Barg Alexej , Ruiz Roxa , Hintermann Beat
Published: January 2022

Category:

Ankle; Ankle Arthritis; Hindfoot

Introduction/Purpose:

While correction of varus alignment at the level of the ankle joint has been investigated extensively after supramalleolar osteotomy (SMOT), the effect on the hindfoot alignment remains unclear. This can be attributed to the limitations of former 2-dimensional radiographic measurements used to quantify the complex 3-dimensional subtalar joint alignment. Therefore, we aimed to determine both the ankle and subtalar joint alignment before and after SMOT using a weightbearing CT and autogenerated 3-dimensional measurements.

Methods:

Twenty-seven patients with a mean age of 53 years (SD=10.1; range=25-73) were retrospectively analyzed in a pre- post study design using weightbearing CT images. Inclusion criteria were correction of ankle varus deformity by either an opening wedge (N=19) or dome osteotomy (N=8). Exclusion criteria consisted of an additional inframalleolar bony correction, i.e. calcaneal osteotomy or subtalar arthrodesis. Corresponding three-dimensional bone models were reconstructed to compute the autogenerated measurements: tibial anterior surface (TAS) -, tibiotalar surface (TTS)-, talar tilt (TT) - and talocalcaneal (TC) angle.

Results:

The pre-operative (TAS=86.9°, SD=4.9; TTS=79.8°, SD=5.6; TT=8.8°, SD=4.3) radiographic parameters of the ankle joint alignment improved significantly compared to the post-operative parameters (TAS=92.4°, SD=4.9; TTS=87.1°, SD=6.3; TT=5.1°, SD=2.7; P<0.05). (Fig. 1A) Radiographic parameters to assess the subtalar joint alignment improved significantly from preoperatively (TCax =42.8°, SD=9.3; TCsag=42.3°,SD=10.9; TCcor =29.5°,SD=11.8) to post-operatively (TCax =37.8°, SD=8.8; TCsag=39.1°, SD=10.6; TCcor=24.6°,SD=9.1; P<0.05). (Fig. 1B)

Conclusion:

A supramalleolar osteotomy is able to correct both the ankle and subtalar joint alignment. However, correction at the level of the subtalar joint accounted for only 3 to 4 degrees, which was less than found for the ankle joint alignment. For cases where a higher correction at the subtalar joint is necessary, we thus suggest adding a calcaneal osteotomy or subtalar arthrodesis to the SMOT.