bluuebunny/crossref_metadata_2025 huggingface dataset:
Disulfiram: A Repurposed Drug in Preclinical and Clinical Development
for the Treatment of Infectious Diseases
Authors: Custodio Marco M. , Sparks Jennifer , Long Timothy E.
Published: January 2022

This article reviews preclinical and clinical studies on the repurposed use of disulfiram (Antabuse) as an antimicrobial agent. Preclinical research covered on the alcohol sobriety aid includes uses as an anti-MRSA agent, a carbapenamase inhibitor, antifungal drug for candidiasis, and treatment for parasitic diseases due to protozoa (e.g., giardiasis, leishmaniasis, malaria) and helminthes (e.g., schistosomiasis, trichuriasis). Past, current, and pending clinical studies on di-sulfiram as a post-Lyme disease syndrome (PTLDS) therapy, an HIV latency reversal agent, and intervention for COVID-19 infections are also reviewed.
Results of endoscopic treatment of benign prostatic hyperplasia in patients with metabolic syndrome
Authors: Rakhmonov O. M. , Shadmanov A. K. , Juraev F. M.
Published: January 2022

The present paper is about the research conducted on the patients with metabolic syndrome and its results of endoscopic treatment of benign prostatic hyperplasia in these patients. It is generally accepted that the size and volume of the prostate gland is the main prognostic factor affecting the intraoperative and postoperative outcomes of endoscopic treatment of BPH. However, with the rapid development of endoscopic instruments and surgical techniques, the size of the prostate tends to have a lesser influence on the outcome of endoscopic BPH treatment. Currently, MS is becoming an increasingly common disease, which in most cases predicts a poor prognosis for treatment of patients with LUTS.
Accountability answers company insurance life based investing against the risk of failure to pay for policyholders
Authors: Santri Selvi Harvia , Yaswirman Yaswirman , Warman Kurnia , Fauzi Wetria
Published: January 2022

The problem of this research is how to regulate investment-based life insurance in Indonesia and the liability of investment-based life insurance companies against the risk of default by policyholders. This study uses a research method that has an empirical juridical type. The study results explain that the regulation of investment-based life insurance in Indonesia is regulated in Law Number 40 of 2014 concerning Business Per Insurance, OJK Regulation Number 23/POJK.05/2015 concerning Insurance Products and Marketing and Decree of the Chairman of BPPM and Financial Institutions Number KEP-104/ BL/2006 concerning Investment-based life insurance products. PP Number 87 of 2019 concerning insurance companies in the form of joint ventures, RI's Financial Decree Number 422/KMK.06/2003 and Director General of Financial Institutions Decree Number 2475/LK concerning investment insurance products and forms of liability of default insurance companies must fulfill the contents of the agreement insurance that gives rise to the rights and obligations of the insured reciprocally. However, Law Number 40 of 2014 concerning Insurance Business does not fully regulate violations in the insurance business and does not regulate how the insurance company is responsible for the company's inability to fulfill insurance claims.
Cruciferous Vegetable Intervention to Reduce the Risk of Cancer Recurrence in Non–Muscle-Invasive Bladder Cancer Survivors: Development Using a Systematic Process
Authors: Yeary Karen H Kim , Clark Nikia , Saad-Harfouche Frances , Erwin Deborah , Kuliszewski Margaret Gates , Li Qiang , McCann Susan E , Yu Han , Lincourt Catherine , Zoellner Jamie , Tang Li
Published: January 2022

Background

Bladder cancer is one of the top 10 most common cancers in the United States. Most bladder cancers (70%-80%) are diagnosed at early stages as non–muscle-invasive bladder cancer (NMIBC), which can be removed surgically. However, 50% to 80% of NMIBC cases recur within 5 years, and 15% to 30% progress with poor survival. Current treatments are limited and expensive. A wealth of preclinical and epidemiological evidence suggests that dietary isothiocyanates in cruciferous vegetables (Cruciferae) could be a novel, noninvasive, and cost-effective strategy to control NMIBC recurrence and progression.

Objective

The aim of this study is to develop a scalable dietary intervention that increases isothiocyanate exposure through Cruciferae intake in NMIBC survivors.

Methods

We worked with a community advisory board (N=8) to identify relevant factors, evidence-based behavior change techniques, and behavioral theory constructs used to increase Cruciferae intake in NMIBC survivors; use the PEN-3 Model focused on incorporating cultural factors salient to the group’s shared experiences to review the intervention components (eg, the saliency of behavioral messages); administer the revised intervention to community partners for their feedback; and refine the intervention.

Results

We developed a multicomponent intervention for NMIBC survivors consisting of a magazine, tracking book, live telephone call script, and interactive voice messages. Entitled POW-R Health: Power to Redefine Your Health, the intervention incorporated findings from our adaptation process to ensure saliency to NMIBC survivors.

Conclusions

This is the first evidence-based, theoretically grounded dietary intervention developed to reduce bladder cancer recurrence in NMIBC survivors using a systematic process for community adaptation. This study provides a model for others who aim to develop behavioral, community-relevant interventions for cancer prevention and control with the overall goal of wide-scale implementation and dissemination.
Prevalence and risk factors of white-coat hypertension and masked hypertension in Shunde District,Southern China:Observational Study (Preprint)
Authors: Huang Yuli , Zheng Haoxiao , Liang Xiaoyan , Huang Chunyi , Sun Lichang , Liu Xiong , Qiu Min , Mai Weiyi , Mai Weiyi
Published: January 2022

BACKGROUND

White-coat hypertension (WCH) and masked hypertension (MH) can increase the risk of target organ damage. Home blood pressure monitoring is an important method for detecting WCH and MH. However, the prevalence and risk factors of WCH and MH in China has been rarely reported.

OBJECTIVE

To explore the prevalence and risk factors associated with white coat hypertension (WCH) and masked hypertension (MH) in Shunde District, Southern China.

METHODS

This study recruited subjects from the Physical Examination Center in Shunde Hospital, Southern Medical University. Office blood pressure and home blood pressure values were collected. The prevalence of WCH and MH was calculated by combining the office blood pressure and home blood pressure values. Multivariate logistic regression was used to explore the related risk factors for WCH and MH.

RESULTS

Four-hundred and sixty-one participants (61% male), with an average age of 49 years, were included. The incidence of WCH and MH was 5.1% and 15.2%, respectively. Multivariate logistic regression analysis showed that smoking (OR=4.71, 95%CI=1.05-21.15) and family history of coronary heart disease (OR=4.51, 95%CI=1.08-18.93) were associated with higher odds of WCH. The associated factors for higher odds of MH were smoking (OR=2.83, 95%CI=1.11-7.23), family history of hypertension (OR=2.17, 95%CI=1.11-4.26) and family history of coronary heart disease (OR=2.82, 95%CI=1.07-7.45).

CONCLUSIONS

WCH and MH are highly prevalent in the health check-up population in Southern China. Out-of-office blood pressure monitoring, especially home blood pressure monitoring with a telemedicine device should be recommended to identity abnormal BP phenotype.

CLINICALTRIAL

It has been registered in the Chinese Clinical Trial Registry(ChiCTR1800018515)
Understanding the Lived Experiences of Patients With Melanoma: Real-World Evidence Generated Through a European Social Media Listening Analysis (Preprint)
Authors: Chauhan Jyoti , Aasaithambi Sathyaraj , Márquez-Rodas Iván , Formisano Luigi , Papa Sophie , Meyer Nicolas , Forschner Andrea , Faust Guy , Lau Mike , Sagkriotis Alexandros
Published: January 2022

BACKGROUND

Cutaneous melanoma is an aggressive malignancy that is proposed to account for 90% of skin cancer–related mortality. Individuals with melanoma experience both physical and psychological impacts associated with their diagnosis and treatment. Health-related information is being increasingly accessed and shared by stakeholders on social media platforms.

OBJECTIVE

This study aimed to assess how individuals living with melanoma across 14 European countries use social media to discuss their needs and provide their perceptions of the disease.

METHODS

Social media sources including Twitter, forums, and blogs were searched using predefined search strings of keywords relating to melanoma. Manual and automated relevancy approaches filtered the extracted data for content that provided patient-centric insights. This contextualized data was then mined for insightful concepts around the symptoms, diagnosis, treatment, impacts, and lived experiences of melanoma.

RESULTS

A total of 182,400 posts related to melanoma were identified between November 2018 and November 2020. Following exclusion of irrelevant posts and using random sampling methodology, 864 posts were identified as relevant to the study objectives. Of the social media channels included, Twitter was the most commonly used, followed by forums and blogs. Most posts originated from the United Kingdom (n=328, 38%) and Spain (n=138, 16%). Of the relevant posts, 62% (n=536) were categorized as originating from individuals with melanoma. The most frequently discussed melanoma-related topics were treatment (436/792, 55%), diagnosis and tests (261/792, 33%), and remission (190/792, 24%). The majority of treatment discussions were about surgery (292/436, 67%), followed by immunotherapy (52/436, 12%). In total, 255 posts discussed the impacts of melanoma, which included emotional burden (n=179, 70%), physical impacts (n=61, 24%), effects on social life (n=43, 17%), and financial impacts (n=10, 4%).

CONCLUSIONS

Findings from this study highlight how melanoma stakeholders discuss key concepts associated with the condition on social media, adding to the conceptual model of the patient journey. This social media listening approach is a powerful tool for exploring melanoma stakeholder perspectives, providing insights that can be used to corroborate existing data and inform future studies.
Kematangan emosi dan penyesuaian perkawinan pada pernikahan usia muda di Kabupaten Tulungagung
Authors: Mayangsari Puput Dwi , Prabowo Adhyatman , Hijrianti Udi Rosida
Published: January 2022

The phenomenon of marriage at a young age is increasing in Tulungagung. Teenagers who decide to marry young will experience some negative impacts, especially if they are not accompanied with a mature emotional state. The purpose of this study was to determine the relationship between emotional maturity and marital adjustment in young marriages. This study uses quantitative methods. Subjects are selected using purposive sampling technique with the criteria of couples who married when their age is less than 21 years old, with a marriage age of 1-5 years in Tulungagung Regency. This study obtained as many as 83 respondents. This study collected data using a scale of emotional maturity and marriage adjustment through google form and then analyzed using the correlation product moment formula. The results showed the value of r = 0.534 (p <0.05) which means that there is a positive relationship between emotional maturity and marital adjustment. The higher the emotional maturity, the higher the marital adjustment. Vice versa, if emotional maturity is low, marital adjustment will also be low.
 
Keywords: Early age marriages, emotional maturity, marital adjustment
Implementasi Kebijakan Pembatasan Bangunan Akomodasi Wisata Dalam Menopang Pariwisata Berkelanjutan
Authors: Okasujana52
Published: January 2022

This article aims to discuss the urgency and implementation of restrictions on tourist accommodation buildings in the Badung Regency. The research data were obtained through observation, literature study, and in-depth interviews with informants, namely officials, actors, and observers of Bali tourism. Data analysis was carried out descriptively-interpretatively from the perspective of tourism studies. The results of the study show that it is very urgent to restrict tourist accommodation buildings in Badung Regency to anticipate the oversupply of the number of available tourist accommodation rooms, as well as to create a healthy tourist accommodation business situation. Implementation of three policies, namely Regional Regulation No. 2 of 2012; Regional Regulation No. 26 of 2013; and Perbud Badung No. 36 of 2014 has been able to hinder the development of new tourist accommodation buildings, and support sustainable tourism development, namely tourism development that supports environmental conservation efforts (Palemahan), increasing the socio-economic welfare of local communities (pawongan), as well as tourism development that is sustainable. support the preservation and development of Balinese traditions and culture
Perlindungan Hukum Terhadap Tenaga Kerja Lokal dalam Undang-undang Nomor 11 Tahun 2020 tentang Omnibus Law Cipta Kerja
Authors: Iswaningsih May Linda , Budiartha I Nyoman Putu , Ujianti Ni Made Puspasutari
Published: January 2022

Regulatory problems and the disharmony of laws and regulations in labor law in Indonesia have forced the government to reform the rules through the omnibus law which aims to reduce the unemployment rate in Indonesia. The concept of a state of law (rechtsstaat) adopted by the Indonesian state includes the protection of human rights as well as legal certainty and is based on the law. Economic development is very important for improving people's welfare. The purpose of this study is to analyze the regulation of the omnibus law of work copyright for local workers in foreign investment companies in Indonesia and the form of legal protection of the omnibus law of work copyright for workers. The type of research used is the type of normative law research with a statutory approach and a conceptual approach. The legal materials used are primary, secondary, and tertiary. The technique of collecting legal materials by analyzing and citing applicable laws and regulations from books, literature, and other sources. The results of the study reveal that the omnibus law concept is one of the breakthroughs to reorganize current regulations. To minimize the occurrence of disharmony and overlapping of existing laws and regulations, the omnibus law is a good plan for structuring regulations. The Indonesian people must formulate new policies that are able to make Indonesia compete with countries in the world to attract investment. These policies must be able to restore the wheels of the slumped Indonesian economy. Regulatory reform is expected to help ensure that laws and regulations in all areas of activity are fully responsive to changing economic, social and technological conditions that surround them.
Perlindungan Hukum Hak-Hak Narapidana Anak di Lembaga
Authors: Pradana Komang Angga , Sugiartha I Nyoman Gede , Sudibya Diah Gayatri
Published: January 2022

Acts against the law against children are now increasing in the country, children are one of the creations of God Almighty as his creation with the age of children under 18 years old or unmarried are still unstable towards behavior, their emotions are still unstable should be more receive full attention in correctional institutions. This study aims to analyze the regulation of the child education system in special coaching institutions and legal protection for child prisoners in special coaching institutions. This type of research uses the normative method, using the Legislative and Conceptual approach. The sources of legal materials used are primary and secondary legal sources. The technique of collecting data on legal materials used is through recording, namely by quoting. The analysis of legal materials used in this research is descriptive-qualitative. The results of the study reveal that the justice and education system is regulated in the Law of the Republic of Indonesia Number 11 of 2012 concerning the Juvenile Criminal Justice System while the legal protection of children is regulated in the Law of the Republic of Indonesia Number 35 of 2014 amendments to Law Number 23 of 2002 concerning Child protection. Correctional officers should better understand and adapt to the conditions and situations of Indonesia without ignoring the methods or procedures for protection carried out by other countries that should be considered and imitated.
Kriminalisasi Terhadap Pekerja Seks Komersial Melalui Online dalam Pembaharuan Hukum Pidana
Authors: Pratama I Gede Yoga , Laksmi Dewi Anak Agung Sagung , Widyantara I Made Minggu
Published: January 2022

Prostitution is behavior that is openly subject to adultery without any marriage bond. Nowadays prostitution is easy to find on various social media. Commercial-related regulations have been regulated in the Criminal Code, Law no. 19 of 2016 concerning Information and Electronic Transactions, Law no. 44 of 2008 concerning Pornography, Law no. 21 of 2007 concerning the Crime of Human Trafficking. This study aimed to examine the criminal law regulation of online sex workers according to positive law and uncover criminal sanctions against online sex workers in the future. This study was designed using normative legal research, with a Legislative approach. The legal materials used were primary legal materials and secondary legal materials. Data were collected using documentation study techniques and literature studies, then analyzed using systematic interpretation techniques. The results of the study indicated that sanctions for pimps are regulated in the Criminal Code, Law no. 21/2007, Law no. 44/2008, and Law no. 19/2016, and only article 284 of the Criminal Code concerning adultery that can ensnare prostitutes and customers if they have a family, and criminal sanctions for commercial sex workers in the future are contained in articles 425 to 428 of the Draft Criminal Code.
Implementasi Prinsip Kehati -hatian dalam Mencegah Kredit pada PT. Buana finance. Denpasar
Authors: Saputra Kadek Ardy Arya , Budiartha I Nyoman Putu , Ujianti Ni Made Puspasutari
Published: January 2022

primer dan sekunder. Bahan-bahan hukum yang telah didapat dari studi kepustakaan dan pendekatan perundang-undangan dianalisis dengan teknik interpretasi sistematis. Hasil penelitian mengungkapkan bahwa Keterangan saksi sangat diperlukan dalam persidangan guna untuk memberikan sanksi yang tepat bagi terdakwa. Hambatan pembuktian dari keterangan saksi yang memiliki hubungan dan ikatan dalam keluarga adalah apabila asas minimum pembuktian tidak dapat dibuktikan. Dapat disimpulkan kekuatan dari keterangan saksi yang tidak mengucap sumpah, maka tidak dapat dianggap sebagai alat bukti, melainkan hanya keterangan yang dipertimbangkan hakim.
Pelepasan Hak atas Tanah bagi Pembangunan untuk Kepentingan Umum PT. Bali Pecatu Graha (Studi Kasus Kerkara Nomor: 65k/pdt/2012/ma)
Authors: Artana Wayan , Laksmi Dewi Anak Agung Sagung , Suryani Luh Putu
Published: January 2022

Currently, land conflicts that occur are generally caused by conflicts of interest with applicable laws and regulations and often inappropriate compensation. This study aimed to examine the legal arrangements for relinquishing land rights for development in the public interest in Indonesia which refers to Law Number 2 of 2012 and uncover legal protections for relinquishing land rights for development in the public interest of PT. Bali Pecatu Graha. The research method used was descriptive-analytical with a normative juridical approach and qualitative juridical analysis. The data used were primary and secondary legal data obtained through card system techniques. The results of the study indicated that the release of the land refers to Law no. 2 of 2012 and Law no. 5 of 1960. Legal protection for PT. Bali Pecatu Graha due to the act of relinquishing land rights must obtain legal certainty of relinquishment of land rights and requires the availability of written, complete and clear legal instruments that are carried out consistently in accordance with the spirit and content of the provisions so that personal interests get optimal legal protection
Sociological Analysis of the Important Characters in Kevin Kwan’s Crazy Rich Asians
Authors: Gusti Ayu Made Rai Suarniti
Published: January 2022

This research is about the sociological problems of five important characters in Kevin Kwan’s Crazy Rich Asian. Rachel Chu is the main character in this story comes from the middle class society. She has a relationships with Nicholas Young who comes from the upper class society. They face a lot of problems especially from Nicholas’s family who doesn’t agree with their relationships. Different society influences the character of someone. That’s why this research is aimed to find out the types of social class and the influence of social class on the character that showed in the story. The data were collected by reading the novel thoroughly then using the note-taking technique before being identified based on the topic. The collected data were descriptively analyzed by using qualitative-descriptive method to classify the types of social class and the influence of social class on the character that found in this novel. Based on the result of the research, it is found that there are three kinds of social class in Kevin Kwan’s Crazy Rich Asian, those are: Upper class, Middle class and Working class. Rachel Chu who comes from the middle class society has a simple personality. She prefers to save her money for food though she is a lecturer in university rather than her boy friend, Nicholas Young who comes from the worthy family. Nick’s family are also live glamor in Singapore. They spend a lot of money for fashion and jewelry. It much different with Rachel’s mom ( Kerry Chu) who originally comes from  working or lower class society. She fulfills her daughter alone and becomes a single parent because she has divorced with her husband when Rachel still child. This condition make Eleanor Young doesn’t agree with the relationships however the power of love between Nick and Rachel defeated everything. Finally, they become a couple.
Translation Methods Found in New Testament Bible of Mark’s Gospel
Authors: Swarniti Ni Wayan
Published: January 2022

Language is one of the important things in human life. By using the language, we can communicate with others. This research tried to analyze the bible translation by using methods of translation theory by Newmark (1988). This research was a qualitative research that focused to analyze the Gospel according to Mark. Bible entitled New Testament (2005) was published by The Indonesian Bible Society for The Gideons International. It was printed by Percetakan Lembaga Alkitab Indonesia. The book consists of 727 pages. Informal method was used to present the results of the analysis. It was the explanation of the translation methods used. Formal method was used to describe the table of the frequency of the translation methods applied in the bible translation found in new testament bible of Mark’s gospel. The translation methods found in data source were word for word translation, literal translation, faithful translation, semantic translation, free translation, idiomatic translation, and communicative translation. Adaptation was not found in all chapters of data source. The most translation method applied in new testament bible of Mark’s gospel was free translation. Free translation had the highest percentage in every chapter in new testament bible of Mark’s gospel. In the other word, the translator tried to transfer the meaning from source text into target text with changing the form based on cultures in target language.
Upaya Pencegahan Kekerasan Terhadap Anak dimasa Pandemi Covid-19
Authors: Wismantari Ni Made , Dewi Anak Agung Sagung Laksmi , Ujianti Ni Made Puspasutari
Published: January 2022

The Covid-19 pandemic has had the worst impact, namely the increased vulnerability of children to become victims of violence. The Covid-19 pandemic has stimulated an increase in cases of violence against children, so in this case a legal protection is needed to fulfill the rights obtained for every child. The purposes of this study are to reveal legal arrangements in an effort to prevent violence against children during the COVID-19 pandemic as well as legal protection for children who experience violence during the COVID-19 pandemic. The research method used in this research is normative legal research with a statutory approach. The technique of collecting legal materials used in this research is the study of documents or library materials. The sources of legal materials used are primary and secondary sources of legal materials. The data analysis techniques were analyzed qualitatively and presented descriptively. The results of the study revealed that the government's efforts to prevent violence against children during the Covid-19 Pandemic were pursued through preventive legal protection with the aim of preventing violations before the occurrence of violations and repressive legal protection in the form of sanctions such as fines, imprisonment, and additional penalties given if a dispute has occurred or has occurred. a violation is committed. All parties, both families and the government, should try to protect children from all acts of violence.
Sanksi Pidana Bagi Kegiatan Mereview Suatu Produk Usaha di Media Sosial Tanpa Izin
Authors: Surya Bagus Andika Artha , Laksmi Dewi Anak Agung Sagung , Suryani Luh Putu
Published: January 2022

In the competitive world of business, one effective way as a means of promotion is reviewing or reviewing products, which are activities carried out by consumers to give their impressions and views about a product so that it becomes a consideration for other consumers before buying the product, but there are negative impacts from this activity, namely if it is misused by irresponsible persons, what happens is that the person gives a bad image to business actors because of these activities and affects consumers who will buy the product. The purpose of this study is to analyze the sanctions that can be imposed from reviewing or reviewing a product that has copyright without permission from business actors. This study applies a normative method with a statutory approach. Data collection techniques were carried out by examining existing library materials. The sources of law used are divided into two, namely primary and secondary sources of law which are then analyzed by methods of legal interpretation, legal argumentation, and legal construction. The results of the study reveal that the activity of reviewing a product is also regulated through Article 27 paragraph (3) of Law 19 of 2016 concerning amendments to Law Number 11 of 2008 concerning information and electronic transactions aimed at protecting brands from good name numbers.
Konservasi Bahasa Bali pada Kegiatan Kesubakan di Desa Mambal
Authors: Umiyati Mirsa
Published: January 2022

Over time, the use of regional languages ​​has changed significantly in its use. Given the ever-evolving times, changing mindsets and lifestyles that demand differences from the previous era. Currently the use of mother tongue or Indonesian and English is more desirable in its application due to the demands of an increasingly advanced era. With this phenomenon, the use of regional languages ​​is slowly becoming less attractive, especially the younger generation. To prevent this from happening, a solution is needed, namely by providing teaching or socialization in the form of conservation and revitalization of local languages. The community service program organized by Warmadewa University which aims to educate and increase the interest of the younger generation regarding the preservation of the Balinese language in cultural activities, this also has a relationship with aspects of culture and language. This activity is carried out using a descriptive qualitative method that describes real phenomena that occur in a society. The result of this dedication is that the younger generation shows an interest in fertility activities in order to continue one of the hereditary cultures that has been recognized by the world, namely Subak.
Pentingnya Penguasaan Fungsi- Fungsi Bahasa Inggris dalam Berbicara
Authors: Ni Wayan Kasni
Published: January 2022

The Akasia study group is an English learning group for elementary and junior high school students located near the Warmadewa University campus. This community service is carried out in Akasia study groups in the form of English language teaching activities. Therefore, the purpose of this community service activity is to improve the English speaking’s skills of students in the Akasia study group. The method applied to this activity is the Communicative Language Taeching in Secondary Level method. In addition, this activity is carried out through the Zoom application. In these service activities, the students of the Akasia study group were enthusiastic and active in participating in learning or training. Students in the Akasia study group were given several English functions that were often used, namely greeting, asking name, and asking date, time, day year.
PKM Teknologi Fermentasi Pakan Jerami Padi dan Pembuatan Pupuk Organik Pada Kelompok Ternak “Sato Luwih” Desa Kenderan Kecamatan Tegalalang-Kabupaten Gianyar
Authors: Sudita I Dewa Nyoman , Situmeang Yohanes Parlindungan , Amerta Kadek Suniasta
Published: January 2022

Pemerintah daerah provinsi Bali secara terus menerus mendorong masyarakat petani ternak untuk membentuk kelompok-kelompok ternak khususnya ternak sapi induk, melalui program Simantri sejak tahun 2009/2010 dan sekarang disebut dengan Sipadu. Selain program tersebut juga terbentuk kelompok ternak secara mandiri oleh petani ternak yang tersebar di Bali, salah satunya adalah kelompok ternak “Sato Luwih”di Desa Kendran, Tegalalang-Gianyar, yang memerlukan pembinaan dan pendampingan dalam pemberdayaan sumber daya yang dimiliki yaitu ternak dan limbah yang dihasilkan. Kelompok ternak yang ada di desa Kendran ini baru terbentuk pada awal tahun 2020, dimana para anggotanya memiliki kemampuan yang berbeda dalam beternak baik yang sudah berpengalaman maupun yang baru mulai belajar beternak. Disamping itu sumber daya yang ada berupa limbah ternak sapi belum dimanfaatkan, disatu sisi limbah terbut masih memiliki potensi untuk menambah pendapatan kelompok apabila diolah menjadi pupuk organik kompos. Masalah yang dihadapi oleh kelompok dan anggota kelompok adalah masih kurangnya pengetahuan dalam manajemen pemberian pakan ternak memanfaatkan jerami padi, pengetahuan tentang teknologi pengolahan limbah kotoran sapi baik faeces maupun urine menjadi pupuk organik, dan kurangnya pemahaman tehadap penggunaan pupuk organik kompos dalam sistim usaha taninya. Oleh karena itu melalui  kegiatan PKM perlu diberikan pendampingan dan transfer teknologi terapan pada para anggota kelompok, sehingga pendayagunaan sumber daya yang dimilki dapat dimanfaatkan secara optimal. Metode yang digunakan dalam kegiatan PKM ini yaitu : observasi dan diskusi kelompok, penyuluhan, dan praktek lapang. Diskusi kelompok dilakukan dengan melibatkan para pengurus kelompok untuk menentukan pemberian materi kegiatan dan jadwal pelaksanaan. Penyuluhan dilakukan kepada semua anggota kelompok tentang pembuatan fermentasi pakan jerami dan pembuatan pupuk organik kotoran ternak sapi. Sedangkan praktek dilakukan secara langsung dikerjakan oleh anggota kelompok, dan telah dilakukan evaluasi hasilnya. Hasil PKM didapatkan para anggota kelompok telah mampu melakukan pembuatan fermentasi jerami sebagai pakan ternak dan memanfaatkan limbah kotoran ternak menjadi pupuk organik, sehingga dapat menjaga kebersihan lingkungan kandang. Dari kegiatan PKM ini dapat disimpulkan sudah terjadi perubahan prilaku pada anggota kelompok yaitu pengetahuan dan ketrampilan, sedangkan perubahan sikap masih perlu diadakan observasi lapangan.
Program Pengembangan Desa Mitra: Kelurahan Semarapura Kaja Menuju Wisata Terintegrasi
Authors: Yasa Putu Ngurah Suyatna , Mardika I Made , Laksmi A. A. Rai Sita
Published: January 2022

PPDM tentang “Pemberdayaan Masyarakat dalam Mewujudkan Wisata Terintegrasi di Kelurahan Semarapura Kaja, Klungkung” menjadikan lurah dan kelompok-kelompok Masyarakat Kelurahan Semarapura Kaja sebagai mitra dan khalayak sasaran. Semarapura Kaja dipilih sebagai lokasi pengabdian karena kawasan ini kaya akan potensi wisata, mendapat dukungan pemerintah Kabupaten Klungkung, dan mengajukan permohonan untuk dijadikan desa binaan Program Pascasarjana Universitas Warmadewa. Tujuan PPDM adalah untuk memberdayakaan masyarakat dalam rangka menyiapkan, merancang dan mengembangkan berbagai potensi wisata yang dimiliki. Prioritas program menyangkut pemberdayaan masyarakat, penataan lingkungan, penyiapan informasi dan promosi wisata. Permasalahan yang dihadpi mitra meliputi: (1) Belum trampilnya Pokdarwis Kelurahan Smarapura Kaja berkomunikasi dengan bahasa Inggris, (2) Belum ada informasi dalam bentuk dokumen tentang DTW di Kelurahan Semarapura Kaja, (3) Belum dimilikinya fasilitas umum berupa MCK sebagai sarana penunjang wisata, (4) Manajemen pengelolaan dan pemasaran UMKM di Kelurahan Semarapura Kaja belum maksimal, dan (5) Belum ada inovasi pelayanan publik. Solusi yang ditawarkan adalah Pemantapan ketrampilan bahasa Inggris kepada Pokdarwis, Penyusunan brosur informasi wisata, pengadaan/pembangunan MCK, Penyuluhan dan pendampingan manajemen pengelolaan dan pemasaran kepada UMKM, Pelatihan dan pendampingan pembuatan aplikasi pelayanan public berbasis android. Hasil PPDM tahun kedua mencakup: (1) pelaku UMKM memiliki ketrampilan pemasaran secara online dengan medsos, (2) Bangunan MCK di Pura Tirta Celempung, (3) ketrampilan bahasa Inggris Pokdarwis meningkat, (4) tersedianya aplikasi berbasis android untuk pengurusan surat-surat, dan (5) brosur informasi wisata tersedia.
KAJIAN PERUBAHAN PEMANFAATAN LAHAN DI PESISIR DESA KELAN KELURAHAN TUBAN KECAMATAN KUTA KABUPATEN BADUNG
Authors: I Made Agus Sumardita
Published: January 2022

Perubahan signifikan telah terjadi pada pesisir Pantai Kelan. Awalnya pesisir Pantai Kelan didominasi oleh area tambatan perahu nelayan telah berubah pemanfaatanya menjadi kafe-kafe dan tempat atraksi wisata. Penelitian ini bertujuan untuk mengetahui fenomena perubahan pemanfaatan lahan di pesisir Pantai Kelan pasca diundangkannya Perda Nomor 26 tahun 2013 tentang RTRW Kabupaten Badung yang dapat dikelompokan menjadi (i) mengetahui karakteristik pemanfaatan lahan pada kawasan pesisir Desa Kelan Kelurahan Tuban Kabupaten Badung pasca tahun 2013-2017 (ii) mengevaluasi kesesuaian penggunaan lahan tahun 2013-2017 terhadap RTRW di wilayah pesisir Desa Kelan tahun 2013-2017 (iii) mengetahui strategi pengendalian pemanfaatan lahan pada kawasan pesisir Desa Kelan Kelurahan Tuban agar sesuai dengan RTRW yang telah ditetapkan. Jenis penelitian yang digunakan dalam penelitian ini adalah jenis penelitian kualitatif dengan pengkajian data deskriptif yang dituangkan dalam bentuk laporan atau uraian selain itu sifat penelitian adalah penelitian lapangan yakni data yang dianalisis diperoleh melalui wawancara atau observasi langsung. Metode ini dipilih untuk menggambarkan kecenderungan perubahan pemanfaatan lahan pada suatu kawasan, faktor-faktor yang mempengaruhi perubahannya, serta ketidaksesuaian dengan rencana tata ruang kawasan yang ada. Adapun kesimpulan dari penelitian ini adalah (i) pertumbuhan penduduk mengakibatkan meningkatnya kebutuhan pemanfaatan ruang (ii) pemanfaatan lahan di pesisir Pantai Kelan yang tidak sesuai dengan RTRW (iii) strategi pengendalian pemanfaatan lahan yang perlu di kaji kembali (iv) pemanfaatan lahan pada pesisir Pantai Kelan yang tidak memperhatikan lingkungan menimbulkan kesemberawutan dan berkurangnya teritori nelayan.
Akademik Personelin Ofislerindeki Ergonomik Düzenlemeye Göre Ağrı, Stres ve Fiziksel Aktivite Düzeylerinin Karşılaştırılması
Authors: AKYÜREK Gökçen , ÜSTÜN Betül
Published: January 2022

Amaç: Bu çalışma, üniversitede çalışan akademik personelin, çalışma ortamlarındaki ergonomik durumlarına göre ağrı, stres ve fiziksel aktivite düzeylerinin karşılaştırılmasını incelemek amacıyla yapılmıştır. Materyal ve Metot: Çalışmaya Süleyman Demirel Üniversitesi’nde çalışan 85 gönüllü birey katılmıştır. Bireylerin fiziksel aktivite düzeylerini belirlemek amacıyla Uluslararası Fiziksel Aktivite Anketi – Kısa formu (UFAA), ağrı düzeylerini belirlemek için İskandinav Kas İskelet Sistemi Sorgusu, stres düzeylerini belirlemek için ise Algılanan Stres Ölçeği (ASÖ) uygulanmıştır. Çalışma ortamlarının ergonomik değerlendirmesi ise “Hızlı Ofis Zorlanma Değerlendirmesi (ROSA)” kullanılarak yapılmıştır.Bulgular: UFAA değerlendirmelerine göre, çalışma ortamı ergonomik olan akademik personelin ergonomik olmayan akademik personele göre fiziksel aktivite düzey ortalamalarının istatistiksel olarak daha düşük olduğu görülmüştür (p=0,018). Bunun yanı sıra, algılanan stres seviyesi ortalamalarının her iki grupta da benzerlik gösterdiği görülmüştür (p>0,05). Katılımcıların ağrı düzeyleri İskandinav Kas İskelet Sistemi Sorgusu’na göre akademik personelin son 12 ay içerisinde en çok boyun bölgesinde ağrı yaşadığı, bunu da sırt ve bel bölgelerinde yaşanan ağrıların takip ettiği görülmüştür. Son 12 ay içerisinde yaşanan bu ağrılardan en çok boyun ve bel bölgelerindeki ağrıların bireylerin aktivitelerini engellediği bulunmuştur. Tartışma ve Sonuç: Bu çalışmanın sonucuna göre, üniversitede çalışan bireylerin çalışma ortamlarının ergonomik durumları, bireylerin fiziksel aktivite düzeylerini etkilemektedir. Uzun süren saatler boyunca çalışan akademik personel için fiziksel aktivite düzeylerinin yanında çalışma ortamlarının ergonomik durumuna da dikkat etmeleri önerilmektedir.
Sjögren Sendromlu Hastalarda Aleksitimi ile Depresyon, Anksiyete ve Yaşam Kalitesi Arasındaki İlişkinin İncelenmesi
Authors: ÇETİN Sebahat Yaprak , BALKARLI Ayşe
Published: January 2022

Amaç: Bu çalışmanın amacı Sjögren Sendromlu (SS) hastalarda aleksitimi ile depresyon, anksiyete, yaşam kalitesi, hastalık durasyonu ve inflamatuar belirteçler arasındaki ilişkinin incelenmesidir.
Materyal-metot: Çalışmaya yaş ortalaması 51.14±9.42 yıl olan 168 primer SS’li (pSS) birey (145 kadın, 23 erkek) dahil edildi. Aleksitimiyi değerlendirmek için Toronto Aleksitimi Ölçeği, anksiyete ve depresyonu değerlendirmek için Beck Anksiyete ve Depresyon Ölçeği, yaşam kalitesini değerlendirmek için Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısa Formu Türkçe Versiyonu kullanıldı.
Bulgular: pSS’li bireylere ait aleksitimi ortalaması 53.83±12.61 puan bulundu. Aleksitimi ile anksiyete (r:0.514, p:0.00), depresyon (r:0.522, p:0.00), yaşam kalitesinin ruhsal (r:0.474, p:0.0) ve sosyal (r:0.486, p:0.04) alt parametreleri ve ESR değerleri (r:0.432, p:0.03) arasında düşük ve orta düzeyde anlamlı ilişki bulundu.
Sonuç: Bu çalışmanın sonuçlarına göre pSS’li bireylerde aleksitimi arttıkça depresyon, anksiyete ve inflamatuar belirteç düzeyleri artmakta, ruhsal ve sosyal yönden yaşam kalitesi azalmaktadır. Sonuçlarımız iki yönlüdür. Aleksitiminin pSS'de depresif belirtilerin aracılık ettiği göz önünde bulundurularak, pSS’de aleksitimi, depresyon ve anksiyete gibi psikolojik hastalıkların varlığı ile birlikte tedavi için ayrıntılı değerlendirme ve çok boyutlu bir yaklaşıma olan ihtiyacı desteklemektedir.
Vertebra Fraktürlerinde Unilateral Perkütan Vertebroplasti Tedavisi ve Sonuçlarının Değerlendirilmesi: Tek Merkez Deneyimi
Authors: KANDEMİR Turan , ERTİLAV Kemal , ATAİZİ Zeki Serdar
Published: January 2022

Amaç: Çalışmamızda unilateral perkütan vertebroplasti yapılan hastaların işlem uygulanan vertebra seviyesi, endikasyonların değerlendirilmesi ve uygulamamızın etkinliğini analiz etmeyi hedefledik.
Materyal-Metod: Çalışmamız XXXXXXX XXXXXX Hastanesi Beyin ve Sinir Cerrahisi kliniğinde Ocak 2015 - Ağustos 2019 tarihleri arasında unilateral perkütan vertebroplasti uygulanmış 80 hastanın preoperatif ve postoperatif erken dönem ağrıları için uygulanan görsel analog skala (VAS) skorları, yaşları, cinsiyetleri, işlem uygulanan vertebra seviyesi ve sayısı, etiyolojik nedeni, kronik hastalık varlığı ve osteoporoz varlığı verileri dökümente edildi.
Bulgular: Çalışmaya dahil edilen 80 hastanın toplamda 89 vertebrasına işlem uygulandı. İşlem uygulanan vertebraların 24’ ü torakal 65’ i ise lomber lokalizasyondaydı. En fazla L1 seviyesine uygulandı. Hastaların preoperatif ve postoperatif nörolojik bulgularında bir değişiklik saptanmadı. İşlem sırasında 4 hastada sement kaçağı görüldü. Bu da komplikasyon oranımızın % 5 olduğunu gösterdi. Preoperatif VAS değeri ile postoperatif VAS değerleri arasında anlamlı bir fark saptandı (P<0,001).
Sonuç : Unilateral perkütan vertebroplasti de maruz kalınan radyasyon oranın daha az olması, ameliyat süresinin kısalığı, komplikasyon oranlarının az olması nedeniyle avantajlı bir tekniktir.
Moebius Sendromlu Hastada Dental Tedavi: Olgu Sunumu
Authors: CANDAN Merve , KAPTAN Arife
Published: January 2022

Kraniyofasiyal anomalilerin sık görüldüğü Moebius sendromunun(MS) insidansı tam olarak bilinmemektedir ve çevresel&genetik faktörlerin kombinasyonundan kaynaklandığı düşünülmektedir. MS’nin belirti ve semptomlarının çoğu, 6. ve 7. kraniyal sinirlerin yokluğundan veya az gelişmesinden kaynaklanır. Kraniyofasiyal anomaliler de MS'nin öne çıkan semptomları arasındadır. MS'de mikrognati, kısa veya alışılmadık şekilli dil ve mikrostomi görülebilir. MS'li çocukların dental tedavilerinin genel anestezi altında yapılması gerekebilir. Ancak genel anestezi sırasında dikkat edilmesi gereken bazı durumlar vardır. Bu sendromdan etkilenen bireylerin yaşam kalitesi olumsuz etkilenir ve genellikle özel bakıma ihtiyaç duyarlar. Bu olgu sunumu, MS’li bir çocuğun klinik ve dental bulgularını, diş tedavisi sırasında karşılaşılan klinik durumları ve zorlukları ele almaktadır. Moebius sendromlu hastaların değişken oral belirtileri göz önüne alındığında, bu hastaların klinik takibinin diş hekimlerinin de yer aldığı multidisipliner bir yaklaşım gerektirdiği açıktır.
Impact of the Dental Anatomy Course Trainings on the Psychomotor Skills of Students
Authors: EROĞLU Erdal , BAŞAĞAOĞLU DEMİREKİN Zeynep , ERKEN Merve
Published: January 2022

Objective: To evaluate the impact of the dental anatomy course on the psychomotor skills of dental students.Material Methods: The study was carried on 121 volunteer students of the dental anatomy course. The 9-hole-peg- test (9-HPT) was used for psychomotor skills assessment at the beginner vs. experienced status (fall vs. spring terms). Test completion time in seconds (sec) was used as primary data. Dominant (DH), and non-dominant hand (N-DH), gender, academic success at the higher education admission test (GPA), and the course’s final assessment scores of training were used as variables. Data were analyzed with IBM SPSS V23. Paired samples t-test, the MANOVA test, and Spearman's rho correlation were used for statistical analyses (p<0.05).Results: The participants' DH scores improved from 20.55±2.48 to. 18.32±1.84 sec (p≤0.001), while N-DH scores improved from 22.78±2.66 to 20.52±2.52 sec (p≤0.001). Female's DH scores were 20.16 ± 2.37 vs. 17.90 ± 1.59 sec (p≤0.001), the N-DH scores were 22.40 ± 2.48 vs. 19.83 ± 1.95 sec (p≤0.001) among the fall and spring terms, respectively; while males’ DH scores were 21.30 ± 2.56 vs. 19.13 ± 2.04 sec (p≤0.001), and the N-DH scores were 23.52 ± 2.86s vs. 21.88 ± 2.95 sec (p=0.003). Females’ DH scores were better than males for fall (p=016) and spring (p≤0.001) terms, and N-DH scores were better for fall (p=027) and spring (p≤0.001) terms. Neither GPA nor 9-HPT scores affected the course’s end-of-term practical exam notes.Conclusion: The dental anatomy course significantly contributes to the psychomotor proficiency development of the students.
Fundamental thresholds of realistic quantum error correction circuits from classical spin models
Authors: Vodola Davide , Rispler Manuel , Kim Seyong , Müller Markus
Published: January 2022

Mapping the decoding of quantum error correcting (QEC) codes to classical disordered statistical mechanics models allows one to determine critical error thresholds of QEC codes under phenomenological noise models. Here, we extend this mapping to admit realistic, multi-parameter noise models of faulty QEC circuits, derive the associated strongly correlated classical spin models, and illustrate this approach for a quantum repetition code with faulty stabilizer readout circuits. We use Monte-Carlo simulations to study the resulting phase diagram and benchmark our results against a minimum-weight perfect matching decoder. The presented method provides an avenue to assess fundamental thresholds of QEC circuits, independent of specific decoding strategies, and can thereby help guiding the development of near-term QEC hardware.
Strongly nonlocal unextendible product bases do exist
Authors: Shi Fei , Li Mao-Sheng , Hu Mengyao , Chen Lin , Yung Man-Hong , Wang Yan-Ling , Zhang Xiande
Published: January 2022

A set of multipartite orthogonal product states is locally irreducible, if it is not possible to eliminate one or more states from the set by orthogonality-preserving local measurements. An effective way to prove that a set is locally irreducible is to show that only trivial orthogonality-preserving local measurement can be performed to this set. In general, it is difficult to show that such an orthogonality-preserving local measurement must be trivial. In this work, we develop two basic techniques to deal with this problem. Using these techniques, we successfully show the existence of unextendible product bases (UPBs) that are locally irreducible in every bipartition in d⊗d⊗d for any d≥3, and 3⊗3⊗3 achieves the minimum dimension for the existence of such UPBs. These UPBs exhibit the phenomenon of strong quantum nonlocality without entanglement. Our result solves an open question given by Halder et al. [Phys. Rev. Lett. 122, 040403 (2019)] and Yuan et al. [Phys. Rev. A 102, 042228 (2020)]. It also sheds new light on the connections between UPBs and strong quantum nonlocality.
PENGARUH COKELAT HITAM TERHADAP INTENSITAS NYERI DISMENORE PRIMER PADA MAHASISWI AKADEMI KEBIDANAN SALEHA BANDA ACEH
Authors: Febriansyah Evan , Nuha Kaifar , Kamal Shela
Published: January 2022

Perempuan merupakan makhluk yang memiliki sistem reproduksi yang cukup unik yaitu mengalami haid setiap bulannya. Perempuan yang mengalami menstruasi, biasanya mengalami nyeri dengan tingkat dan sifat yang berbeda-beda mulai dari nyeri ringan hingga nyeri berat. Kondisi tersebut dinamakan Dismenorhea, yaitu suatu keadaan simptomatik yang meliputi nyeri abdomen, kram dan sakit pada bagian punggung saat menstruasi yang dapat mengganggu kegiatan sehari-hari. Angka kejadian dismenorea tipe primer di Indonesia sekitar 54,89% pada wanita usia subur. Mengkonsumsi dark chocolate diketahui dapat meningkatkan jumlah magnesium dalam tubuh dan mengurangi rasa sakit saat menstruasi. Penelitian ini bertujuan untuk mengetahui pengaruh cokelat hitam terhadap penurunan nyeri dismenorhae primer. Penelitian ini merupakan penelitian kuantitatif dengan jenis penelitian quasi eksperimen. Desain yang digunakan pada penelitian ini adalah one group pretest–posttest desain. Adapun sampel pada penelitian ini adalah mahasiswi akademi Kebidanan Saleha Banda Aceh yang mengalami dismenorhea ditetapkan sebanyak 30 orang sebagai kelompok perlakuan dengan teknik pengambilan sampel non-probability sampling, yaitu  quota sampling.KelompokPeneliti akan mendatngi sampel saat sampel mengalami dismenorhea, lalu meminta sampel mengisi ukuran skala nyeri sesuai yang dirasakan, lalu sampel akan cokelat hitam batang 72% sebanyak 35 gram untuk dikonsumsi dan tingkat nyeri akan diukur lagi 2 jam setelah cokelat dihabiskan. Berdasarkan hasil perhitungan uji Wilcoxon menunjukkan bahwa nilai signifikansi (Sig.) sebesar 0,000 kurang dari α (α=0,05). Hal ini menunjukkan terdapat perbedaan bermakna antara skala nyeri dismenorhea sebelum dan sesudah diberikan cokelat hitam. Mengkonsumsi cokelat hitam 72% sebanyak 35 gram berpengaruh terhadap penurunan intensitas nyeri haid dismenorhae primer pada remaja.