bluuebunny/crossref_metadata_2025 huggingface dataset:
Analytical Evaluation of Abhraka Bhasma Samples after Marana, Amritikarana and Lohitikarana
Authors: Arya S Varma  , Satyanarayana Bhat  , Dinesh Nayak
Published: February 2024

Rasaushadhies or herbo-mineral formulations undergo rigorous processes to convert into nano size. The particle size does matters a lot in terms of absorption, assimilation and proper excretion from the body. The pharmaceutical procedures should be strictly adhered so as to ensure safety and efficacy. Abhraka bhasma is a popularly used formulation in Ayurvedic practice. Abhraka or black mica is a bad conductor of heat. So the process of Bhasmikarana requires high quantum of heat in order to render into Bhasma form. Amritikarana is a specific process included in the preparation of Abhraka bhasma. The current study evaluates the essentiality of this process in Bhasmikarana. A detailed analytical study is been carried out to find the differences in the samples before and after Amritikarana. The present study reveals that the particle size has reduced much and the iron content was at maximum concentration in the samples after the process of Amritikarana and Lohitikarana.
Role of Basti and Snehana Putapaka in the Management of Shushkaakshipaka with respect to Sjogren’s Syndrome
Authors: Rutuja Mahendra Jadhav  , Nutan Radaye
Published: February 2024

Sjogren’s syndrome is an autoimmune disorder in which the immune system attacks the glands that make moisture in the eyes, mouth, and other parts of the body. The triad of Sjogren’s syndrome consists of keratoconjunctivitis sicca (dry eye), xerostomia (dry mouth) and rheumatoid arthritis. From Ayurvedic perspective, the pathophysiology of Sjogren’s shows Vata dosha dushti leading to Sandhigata vikara, Roukshya and Shushkaakshipaka. Shushkaakshipaka is a Vata-pittaja, Sarvagata netra vikara that matches the clinical picture of dry eyes disease. To control this Prakupit vata dosha; Sanshodhan and Shaman both are required. As a result, Vata shodhana was achieved by Basti upakram and Basti pashchat Snehana Putapaka, Nasya and Snehapana brought about Vata shamana. Patient’s dryness of eyes was assessed using Schirmers test and Tear film Break up test. After treatment Schirmer’s reading showed significant improvement from 2mm to 10mm and from 4mm to 8mm in right and left eye respectively. Other symptoms of patient like dryness of mouth and joint pain also reduced to a certain amount. This case report shows a classical Ayurvedic treatment protocol used to treat Sjogren’s Syndrome.
An Antimicrobial Evaluation of Bhasmeshwara Rasa on Salmonella Typhi
Authors: J M Urvashiba  , BN Ashok Kumar  , A Ravindra  , V S Sushmitha  , P R R Geethesh
Published: February 2024

Infections can be caused by a wide range of pathogens and bacteria are one among them. Presently, we confront a significant challenge concerning antimicrobial resistance, leading the world to explore alternative medicine as a potential solution. Bhasmeshwara rasa is a formulation mentioned under Sannipataja jwara chikitsa in Rasendra Chintamani which acts on all three Doshas. It is a Khalviya Rasayana containing Vanyopala bhasma (cow dung cake Bhasma), Maricha and Shuddha vatsanabha and its Anupana is Ardraka Swarasa.

Even though there is no Parada used in this formulation, still this formulation is suffixed with “Rasa” in its name Bhasmeshwara. In vitro anti-bacterial study, the action of Bhasmeshwara rasa was tested against Salmonella typhi by well diffusion method. A combination of Bhasmeshwara Rasa and Ardraka Swarasa showed antibacterial activity against Salmonella typhi. Hence, with the present study, it can be concluded that Bhasmeshwara Rasa and Ardraka Swarasa combination shows mild to moderate anti-bacterial activity.
A Case Series on Importance of Rukshana Therapy in Spinal Pathology
Authors: Nutan Mahato  , Sudarsana Kaveri R.N  , Shylamma T.M  , Bindu P.R
Published: February 2024

Spinal pathologies like cervical spondylosis and lumbar spondylosis have become very much prevalent due to lifestyle and environmental factors. Neck pain and low back pain is the leading cause of years lived with disabilities. Ayurveda always insisted on intervening at the early stage of every disease so that the progress of pathology can be prevented. To counteract these conditions, Ayurveda has put forth six-fold treatment methodologies called Shadupakrama. Rukshana is one among them which can be used as both Bahiparimarjana and Antahparimarjana chikitsa. With Rukshana therapy, the body’s oily, sticky, fatty constituents are dried up and reduced. In this case series, three cases related to spinal pathology, especially cervical and lumbar spondylosis were successfully treated by incorporating the principle of Rukshana. Initially, the condition was visualized as Kaphavruta Vata/Vataanubandha Kapha. Hence the first line of treatment should be Kaphavatahara.  Apart from these there is the involvement of Ama in the Samprapthi and considering all these factors internally Rukshana was attained via oral medications and externally by Rukshana upakrama. After the Rukshana therapy patient shows marked improvement, assessments were recorded by comparing the grade of pain, joint tenderness, and range of motion before and after treatment. Notable changes are evidence that the Ayurvedic way of approach to treating spinal disorders is effective and successful. After Rukshana karma, Snigdha bahya karma was adopted along with some internal medications.
Role of Uttarabasti in Neurogenic Urinary Incontinence
Authors: Athira V. Kottoor  , Sunil John Thykkattil
Published: February 2024

Neurogenic bladder refers to dysfunction of the urinary bladder arising from internal or external trauma, disease, or injury of the central, autonomic or somatic nervous system in the control of micturition. Depending on the nerves involved and the nature of the damage, bladder becomes either overactive or underactive and this usually presents clinically as urinary incontinence or retention of urine. Urinary Incontinence (UI) is a hygienic problem and is one of the troublesome, important cause of morbidity and impairment of quality of life, in both men and women. It may lead to recurrent UTI and ascending infections which affect the functioning of kidney. Deranged function of Vatadosha especially Apanavata along with Pranavata and Vyanavata are the main culprits of neurogenic bladder. Vitiated Doshas cause Mootravahasrotodushti and Atipravritti of mootra. This case study discusses the effect of Mootramarga uttarabasti in reducing the signs and symptoms of neurogenic urinary incontinence and thereby improving the quality of life. A 66 year old male patient was admitted with weakness in left upper and lower limbs, slurred speech, and difficulty in controlling micturition since 5 months. He was a diagnosed case of stroke on the basis of a brain computed tomography scan. During the course of management, Uttarabasti was administered for 8 days with Dhanwantarataila and Balamoolakashaya alternatively. The intervention resulted in reducing the symptoms of neurogenic urinary incontinence as evidenced by the reduction in ICIQ-UI -SF score. It was observed that the overall impact of the disease was reduced and quality of life improved with the help of King’s Health Questionnaire (KHQ).
Determination of Polyphenolic Compounds Present in Guduchyadi Kashaya Using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Authors: Sruthi S S  , S Anand
Published: February 2024

The utilization of various contemporary analytical methods has become indispensable when it comes to assessing polyherbal Ayurvedic formulations, aiming to ensure their quality, safety, and effectiveness. Quality control of herbal medicines involve analytical evaluation using instrumental techniques such as TLC, HPTLC, HPLC, GC-MS, LC-MS and spectrophotometer etc. Among them Liquid Chromatography with tandem Mass Spectrometry (LC-MS/MS) is a powerful hyphenated analytical technique that combines the separating power of liquid chromatography with the mass analysis capabilities of mass spectrometry. Generally, its application is oriented towards the specific detection and potential identification of chemicals in a complex mixture. Polyphenolic compounds are usually referred to as a diverse group of naturally occurring compounds containing multiple phenolic functionalities. The anti-inflammatory, anti-aging, antiproliferative, and antioxidant like biological properties of phenolic compounds have been described in several studies. This research study was taken to analyse polyphenolic compounds in Guduchyadi kashaya by LC-MS/MS. Phenolic compounds are abundant in the ingredients of Guduchyadi kashaya, as evidenced by previous studies. So, to determine the polyphenolic contents of Guduchyadi kashaya, this study was conducted. The quantification of the polyphenols was carried out on Shimadzu Shim Pack GISS C18 column with .1%formic acid as mobile phase. A total of 28 polyphenolic compounds were analysed, and 24 of these compounds were found to be present in Guduchyadi kashaya. The results showed that the phenolic compounds present in the ingredients were also present in the formulation in high abundance.
Ayurvedic Management of Visarpa w.s.r to Herpes Zoster
Authors: Vijetha S  , Basavarajeshwari  , M B Rudrapuri  , G Vinay Mohan
Published: February 2024

Visarpa is one of the major Skin disease which is widely explained in our Ayurvedic classics. The clinical features contemplates with Herpes Zoster which is an active transmitting Viral disease. This case reports shows the Successful treatment of Visarpa. Here presenting a case of 72 year, female with sudden onset of 2-3 Vesicles on an Erthyematous base over the chin and left half of the lower lip, along with dragging pain and burning sensation within 2 days. Gradually Vesicles started to appear over the left side of the face, left Ear, Tongue with increased number of Vesicles within 4-5days along with other symptoms persists. Clinically the patient was diagnosed as Visarpa (Herpes Zoster). As Pitta Dosha and Raktha Dhathu vitiation was noticed, managed by Siravyadha as Shodhananga chikitsa and the Dravyas with Tiktha Rasa, Sheetha veerya in nature. The patient showed improvement within 15days of Treatment. The detailed case is presented in the full paper.
Herbal Medicine: A Promising Approach for the Treatment of Alzheimer's Disease
Authors: Thirupathirao Vishnumukkala  , Prarthana Kalerammana Gopalakrishna  , Saravanan Jagadeesan  , Samaila Musa Chiroma  , Nurul Huda Mohd Nor  , Mohamad Taufik Hidayat Baharuldin  , Warren Thomas  , Mohamad Aris Mohd Moklas
Published: February 2024

Alzheimer's disease is a progressive neurodegenerative disease manifesting in cognitive decline, impairment of memory, and behavioural deterioration. Alzheimer’s is a relatively common type of dementia. The pathological basis for the progression of Alzheimer's disease is beta-amyloid protein accumulation, phosphorylation of tau protein, abnormal glial cell function, inflammation, neurotransmitter imbalance, along with oxidative stress in brain tissue. Current available therapies are targeted at amelioration of symptoms alone and focus on a limited spectrum of pathophysiological processes. It is evident that it is essential to develop a multi-target therapeutic option in managing Alzheimer's disease, in view of the broad range of factors in disease progression and sever consequences for sufferers. Herbal medicines are seen as a potential resource in the treatment of Alzheimer's disease, in view of their historical use in traditional medicine as neuroprotectants. Herbal medicines have been evaluated in animal studies designed to determine their capacity to prevent neurodegenerative disease and ameliorate memory defects. This review elaborates on the studies conducted on several medicinal plants that have been investigated for their potential in the prevention and treatment of memory defects in animal models.
Pemberian Sanksi Hukum Bagi Perusahaan Berbadan Hukum Perseroan Terbatas (PT) dalam Pelanggaran Kewajiban Coorporate Social Responsibility
Authors: Yahya Michael Gerarrldino , Reykasari Yunita
Published: February 2024

Perusahaan yang merupakan badan usaha dan berada di tengah masyarakat harus memperhatikan kondisi lingkungan maupun masyarakat yang terdapat disekitarnya sehingga yang tidak merusak ataupun berdampak merugikan, setidaknya tentang menghilangkan atau mengurangi dari dampak negatif dari pendirian serta kegiatan produksi perusahaan. Untuk mengetahui pengaturan sanksi hukum bagi PT yang tidak melakukan kewajiban Coorporate Social Responsibility berdasarkan studi dari Putusan MK RI No. 53/PUU-VI/2008 tentang Judicial Review Pasal 74 Undang-Undang No. 40 Tahun 2007 tentang PT. Pendekatan yang dilaksanakan melalui cara melangsungkan telaah terhadap seluruh undang-undang maupun peraturan yang mempunyai keterkaitan terhadap isu hukum yang sedang dihadapi. Hendaknya pemerintah selaku pembuat undang-undang lebih ditegaskan lagi perarturan tentang sanksi dari pelanggaran Coorporate Social Responsibility di pasal yang sudah dijelaskan agar tidak menimbulkan kekaburan norma. Metode penelitian yang digunakan ialah yuridis normatif dan yuridis empiris dengan pendekatan perundang undangan dan pendekatan konseptual. Tujuan dilakukan penelitian ini untuk mengetahui pengaturan sanksi hukum bagi perusahaan yang tidak menjalankan kewajiban CSR berdasarkan studi dari putusan Mahkamah Konstitusi RI No.53/PUU-VI/2008 tentang judicial review  pasal 74 Undang-undang No.40 Tahun 2007 tentang PT.
Perbandingan Metode Linier Greenshield Dengan Metode Logaritmik Greenberg Terhadap Penyempitan Jalan (Studi Kasus Jalan Poros Mappanyukki Rantepao Kab. Toraja Utara )
Authors: Palayukan Resti Octavia , Rangan Parea Rusan , Bokko Jacob , Miri' Gersony , Juniati Klesia Restu
Published: February 2024

Penelitian yang menitiberatkan pada studi kasus perbandingan dua Metode yang berbeda untuk menganalisa proses penyempitan ruas jalan.
Kuat Tekan Beton Menggunakan Material Tanah Mediteran Asal Dusun Kadinge
Authors: Arrang Abdias T , Rangan Parea Rusan , Sendana Salmon , Mapaliey Yulieanti S.
Published: February 2024

Concrete is one of material that is widely used in infrastructure development, this is due to the abundance of concrete building materials available in nature. This study utilizes mediterranean soil as a substitute for fine aggregate and cement substitution to determine the feasibility of the mixed-concrete mediterranean soil against the achieved compressive strength.

In this research, a laboratory experimental study method was used, that is conducting a compressive strength test on sample with the composition of the Mediterranean soil as a fine aggregate substitution of 25% and 50%, and the mediterranean soil passed sieve No. 200 which is heated to a temperature of 400 0 C as a cement substitute for 3% and 5%. The compressive strength of the concrete is 20 MPa with a slump of 100 mm.

The results showed that the compressive strength of 25% and 50% fine aggregate substitution concrete was 20.05 MPa and 13.739 MPa, or only 94.23% and 60% compressive strength of concrete without mediterranean soil (21.235 MPa). Meanwhile, the compressive strength of 3% and 5% cement substitution concrete was 17.74 MPa and 14.53 MPa, or only 83.59% and 68.45% compressive strength of concrete without mediterranean soil.
Human amniotic epithelial cells (HAECS); a potential cell type for the hepatic disorders
Authors: Qurat Ul Ain Khan  , Shumaila Usman  , Kanwal Haneef  , Bushra Wasim Khan  , Talat Mirza
Published: February 2024

Objective: To isolate a homogenous population of human amniotic epithelial cells (hAECs) from the amniotic membrane of the human placenta and differentiate them into hepatic-like cells with the help of small molecules.
Method: hAECs were isolated by using the enzymatic digestion method and characterized for the presence of specific stem cell markers. In-vitro, hepatic differentiation of hAECs was carried out by using a combination of small molecules. Differentiated cells were observed under a live cell imaging microscope for morphological changes followed by gene and protein expression analysis by qPCR and immunocytochemistry respectively.
Results: The isolated hAECs attained characteristic cuboid epithelial shape and express stem cells marker. The hepatic differentiation method was optimized based on soluble chemical compounds supplied in the culture medium. The differentiated hAECs phenotypically acquire hepatic-like cell features and expressed hepatic markers as well as hepatic protein albumin at immature levels.
Conclusion: The isolated population of hAECs is highly proliferative. Moreover, hepatic markers expression in the isolated hAECs makes them an exclusive source for the treatment of chronic liver diseases.
Keywords: Amnion, Immunohistochemistry, Epithelial, Albumins, Liver, Digestion, Placenta
Problem-solving strategies program to strengthen divergent thinking in mathematics in high school students
Authors: Dioses Moran Liliana Amanda , Dios Yamunaque Manuel Maria , Sabino Escobar Carlos Manuel
Published: February 2024

This study investigates the value of developing divergent thinking skills for tackling mathematical learning challenges. Employing a quantitative, applied approach with a quasi-experimental design, the study involved 50 students divided into a control and an experimental group through non-probabilistic sampling. A validated divergent thinking questionnaire, assessed by expert judgment, was used to gather data. While the pre-test results indicated limited problem-solving skills beyond acquiring the final answer, the post-test revealed significant improvements in problem comprehension, coherent reasoning, and analytical solution proposals. These findings suggest that implementing problem-solving strategies can effectively address mathematical challenges and enhance understanding of related concepts.
Rancang Bangun Aplikasi Pengolahan Data Barang Inventaris Berbasis Mobile di Bidang Pemuda dan Olahraga
Authors: Alda Muhamad , Ira Murni  , Bagus Rizki Lubis  , MHD Aria Agung Widodo
Published: February 2024

Inventory processing is an item data management activity carried out through a shopping budget or donations. This application is designed to provide easy access and speed in recording, managing and monitoring inventory in real-time. The aim of this research is to produce an Inventory Application at the Sergai Youth and Sports Office which can be used to process inventory data to make it more effective and accurate. This research uses data collection methods, namely interviews and literature studies, and for application development methods using the waterfall method. The results of this research obtained a system that is useful for processing inventory item data that will be used at the Youth and Sports Sector Office of DISPORAPARBUD SERGAI.
Dark Tourism As A Tourism And Culture Development Strategy In Indonesia
Authors: Khil Wailmi  , Tono Mahmudin  , Riztrya Novedliani  , Randi  , Lutpi Samaduri
Published: February 2024

This research aims to (1) determine the potential for tourism and dark tourism culture in Indonesia; (2) knowing the strategy for developing tourism and culture through dark tourism. This research uses descriptive qualitative research. The data sources used in this research were obtained from books, websites and literature related to dark tourism as a tourism and culture development strategy in Indonesia. The analysis used in this research is SWOT analysis. The results of this research show that (1) the development of the attraction of dark tourism in Indonesia has great potential. Indonesia has a lot of dark tourism with historical and cultural values that attract tourists; (2) strategies for developing tourism and culture through dark tourism include marketing planning for dark tourism as tourism and culture, creating a dark tourism concept, collaborating with tourism agencies and private parties to support dark tourism, and education and promotion of dark tourism programs.
Dampak Investasi Asing di Pulau Komodo
Authors: Satrya Mutthaqin Muhammad , Rafiqoh Lubis Nurul , Batubara Maryam
Published: February 2024

Komodo Island, as Indonesia's famous tourism destination, has attracted foreign investment which has the potential to influence the economic, social and environmental sectors. This investment brings benefits in the form of opening jobs, increasing local community income, and developing tourism infrastructure. However, the impact also creates economic disparities between local and foreign workers, as well as social problems related to cultural interactions and local community access to the benefits of tourism. Meanwhile, developing tourist infrastructure also threatens the Komodo dragon habitat and the Komodo Island ecosystem. Therefore, mitigation measures are needed to ensure foreign investment supports sustainable development and preservation of the Komodo Island ecosystem. This research uses a literature review method which involves analysis from various sources such as scientific journals, books, reports and articles related to the impact of foreign investment on Komodo Island. This research aims to analyze the impact of foreign investment on Komodo Island on the economic, social and environmental sectors. The research focus includes discussing the economic impact through opening jobs and increasing income, the social impact related to cultural interactions, and the environmental impact of tourism infrastructure development.
Faktor-Faktor yang Berhubungan dengan Siklus Menstruasi pada Wanita Usia Subur: Literature Review
Authors: Dhiya Ulhaq Ghina , Wittiarika Ivon Diah
Published: February 2024

Menstruation is associated with sexual maturity, fertility, overall health, and even changes in various parts of the body. The menstrual cycle typically remains relatively stable during the reproductive years. However, 11.7% of adolescent girls in Indonesia experience menstrual cycle disturbances. Therefore, it is essential to identify factors related to the menstrual cycle. The study was a literature review. The literature used consisted of articles from national journals published in the last five years (2018–2023). The literature sources were obtained from "Google Scholar" using the keyword "siklus menstruasi".Five articles meeting the criteria were identified. Factors influencing the menstrual cycle in women of reproductive age included fast food consumption, stress levels, overweight or obesity, sleep quality, physical activity level, and anxiety. Conclusion: Effectively managing stress, maintaining an ideal body weight, ensuring an adequate amount of sleep, avoiding excessive physical activity, and addressing anxiety could contribute to a normal menstrual cycle.
Analisis Kepatuhan dan Kinerja Pengendalian Internal dalam Mengurangi Tingkat Fraud pada Perusahaan
Authors: Selsabila Nur Aprillia  , Zainal Muttaqin
Published: February 2024

The effort to achieve financial accountability and transparency in an organization, various challenges arise, including actions that can lead to fraud. Fraud is a serious threat threats that can cause financial and reputational losses to a company. The purpose of this research is to analyze compliance and the performance of internal controls in reducing the level of fraud in a company. The research method used in this study is qualitative research. The type of research employed is literature study. The research findings indicate that high compliance with internal controls can create a work environment that values transparency, accountability, and integrity, where employees feel safe to report fraud occurrences and support efforts to prevent and take appropriate actions, thus significantly reducing the level of fraud. The performance of internal controls can be measured through the effectiveness of implementing control policies and procedures.
Pengaruh Sistem Akuntansi Pemerintahan (SAP), Implementasi Sistem Keuangan Tingkat Instansi (SAKTI), Kompetensi SDM Melalui Sistem Pengendalian Internal terhadap Kualitas Laporan Keuangan di Lembaga Pemerintah ABC
Authors: Yulianti Sri  , Elwisam
Published: February 2024

This study aims to find out the impacts of the Government Accounting System (Sistem Akuntansi Pemerintahan/SAP), Agency-Level Financial System Implementation (Implementasi Sistem Keuangan Tingkat Instansi/SAKTI), Human Resources Competencies) through the Internal Control System (Sistem Pengendalian Internal/SPI) on the Quality of Financial statements in governmental institutions. This study used a quantitative approach using a questionnaire to obtain its data source and Warppls 7.0 App. There were 100 respondents as samples of this study, comprising the financial managers in the Governmental Institution ABC. The results show that the Government Accounting System (SAP), Agency-Level Financial System Implementation (SAKTI) Implementation, Human Resource Competencies, and the Internal Control System (SPI) have positive and significant impacts on the quality of financial statements of Governmental Institution ABC. The Internal Control System can mediate the impacts of the Government Accounting System (SAP) and the Agency-Level Financial System (SAKTI) Implementation on the Quality of Financial Statements in Governmental Institution ABC. This study's Total Coefficient of Determination is 0,697% or 68,7 &. It means that the model can explain the Information in 68,7% of data. Meanwhile, the remaining is explained by other variables not included in the model.
Manajemen Pembelajaran Pendidikan Agama Islam Melalui Program Pelaksanaan Sholat Dhuha di SMP IT Ad Durrah
Authors: M.Adimas Juanda Panjaitan  , Mario Kasduri
Published: February 2024

This study aims to determine the management of Islamic religious education learning through the dhuha prayer implementation program at smp it ad durrah. The method used in this study is descriptive qualitative research with data collection techniques in the form of in-depth direct observation, interviews and documentation. The location used as the object of study at SMP IT Ad Durrah.  In this study, four data analyses were used, namely data collection, data reduction, data presentation and conclusion drawing. The research findings show that principals and religious teachers plan religious learning through curriculum development and meetings. Religious learning through habituation of dhuha prayers at AD DURRAH IT Junior High School is carried out with good management. This is indicated by the enthusiasm of the students to do wudhu and perform dhuha prayers. Dhuha prayers are performed in Islamic Education subjects. Dhuha prayers are performed by students in grades 1 to 3 of junior high school. However, the place of worship is inadequate. Evaluation is routinely carried out at teacher meetings. The conclusion of this study is that the management of Islamic religious education learning through the dhuha prayer implementation program at AD durrah IT Junior High School provides important learning to students and provides continuous learning for them so as to give birth to religious students not only carrying out the obligatory but living the Sunnah of the Prophet.
PENERAPAN PERMAINAN PUZZLE DALAM MENINGKATKAN KEMAMPUAN MOTORIC ANAK USIA PRASEKOLAH PADA MATEMATIKA
Authors: Rizqi Nur Rahmi , Simamora Yumira , Rokan Najwah
Published: February 2024

Tujuan dari pengabdian ini adalah untuk mengetahui dan menilai penggunaan permainan puzzle sebagai teknik pengajaran untuk meningkatkan kemampuan motorik anak prasekolah dalam kaitannya dengan pembelajaran matematika.Sebagai bagian dari teknik pengabdian ini, anak-anak prasekolah berpartisipasi aktif dalam sesi permainan puzzle yang dirancang untuk meningkatkan perkembangan motorik halus dan kasar. Puzzle tersebut dipilih berdasarkan tingkat kerumitan yang paling sesuai dengan kebutuhan perkembangan balita. Sepanjang pengabdian, informasi diperoleh melalui observasi partisipan, wawancara, dan perekaman video terhadap anak-anak yang sedang bermain. Dalam pengabdian ini menunjukkan bahwa penggunaan permainan puzzle meningkatkan kemampuan motorik anak-anak prasekolah secara signifikan. Selain itu, penggunaan media pembelajaran puzzle juga meningkatkan pemahaman konsep matematika seperti pengenalan bentuk, bilangan, dan pola.
Acute postpartale hypoxemie: een diagnose van reumatisch mitraliskleplijden
Authors: de Mey J. , Janssens U. , Tosi M. , von Kemp B. , Breugelmans M. , Vanhonacker D.
Published: February 2024

Acute postpartum hypoxemia: diagnosis of rheumatic mitral valve disease

Among various causes for peri- and postpartum respiratory insufficiency, rheumatic mitral valve disease is a less common, yet potentially dangerous condition. In Europe, the incidence of rheumatic fever is low, making rheumatic heart valve disease rare. However, as a result of modern migration of patients from endemic regions, one must be aware of possible associated underlying valvular disease in young patients.

A 42-year-old patient of North African ethnicity undergoing an elective C-section develops acute hypoxemia during the procedure, persisting postpartum despite the administration of oxygen. Initially, more obvious causes, such as a high spinal block and an allergic reaction, are excluded. A CT scan formally excludes a pulmonary embolism, but is suggestive of heart failure. A consecutive transthoracic echocardiography confirms acute decompensated heart failure with pathognomonic characteristics of rheumatic mitral valve disease. The patient is admitted to the cardiac intensive care unit, where the administration of oxygen and an intravenous treatment with diuretics have a favorable result. A low-dose beta blocker is initiated prior to discharge 5 days postpartum.

Although rheumatic mitral stenosis is less common in Europe, one should consider this disease entity in the differential diagnosis when confronted with sudden (cardio)respiratory insufficiency in the parturient. Through this case, the authors highlight the implications of rheumatic mitral valve stenosis during pregnancy and the possible triggers for peripartum cardiac decompensation.
THE INFLUENCE OF SUPERVISION, LEADERSHIP, AND MOTIVATION ON THE PERFORMANCE OF EMPLOYEES AT ASAHAN DISTRICT'S HUMAN RESOURCES AND DEVELOPMENT AGENCY
Authors: Rachman Aulia , Zebua Mei Ingatman , Hadianti Ruwaidah , Indasari Isnaini , Lubis Hasrita , Isnaini Dewi Budiarti
Published: February 2024

The question posed by this study is whether employee performance at the Asahan Regency Personnel and Human Resources Development Agency is influenced by supervision, leadership, and motivation simultaneously. This exploration means determining the impact of oversight, authority and inspiration on representative execution at the Asahan Rule Faculty and HR Improvement Organization. This study's sample consisted of all 38 Asahan Regency personnel and Human Resources Development Agency employees. The information examination procedure in this exploration is Numerous Straight Relapses. The consequences of this examination show that halfway oversight significantly affects representative execution; employee performance is influenced in part and significantly by leadership; inspiration somewhat affects representative execution; and management, initiative and inspiration all the while meaningfully affect representative execution.
Investigating the Interplay Between Authentic Leadership Skills and Second Language Proficiency in a Higher Education Institution
Authors: Santos Ramil , Gatchalian Chuckee , Handig Joy Edilaine , Sumugat Mary Grace
Published: February 2024

This research investigates the interplay between authentic leadership skills and second language proficiency, specifically English, among academic leaders in a Higher Education Institution (HEI) in Bulacan, Philippines. In a globalized educational landscape, leadership in HEIs is crucial for institutional success. The study focuses on Authentic Leadership, emphasizing its developmental perspective and four key components: self-awareness, internalized moral perspective, balanced processing, and relational transparency. Concurrently, it explores the impact of English language proficiency on leadership within the context of higher education. Using a descriptive correlational research design, the study sampled supervisory staff at NU Baliwag, employing the Test of English for International Communication (TOEIC) for language proficiency and the Authentic Leadership Self-Assessment Questionnaire for leadership skills. Results indicate a moderate to high level of English proficiency, with a positive correlation between language proficiency and authentic leadership dimensions. The study contributes insights for NU Baliwag, suggesting that enhancing language skills may positively influence leadership development. However, caution is advised in generalizing findings, and the study highlights the need for future research to replicate the study in diverse contexts and consider additional variables for a comprehensive understanding of the dynamics between language proficiency and leadership development in higher education.
Effect of Financial Technology on Financial Performance of Deposit Money Banks in Southwest, Nigeria
Authors: Yusuf Rasheed Adesoye , Ologunwa Oluyemi. P , Obamuyi Tomola. M
Published: February 2024

Financial Technology in the recent times, has significantly intensified competition in Nigerian Banking Industry, hence Deposit Money Banks (DMBs) face persistent pressures from a wide and diverse range of competitors, while the regulatory environment becomes less protective of the financial institutions. This study therefore examined the effect of financial technology on the financial performance of deposit money banks in southwest, Nigeria. The study employed an Ex-Post Facto research design to establish functional relationship among customers and employees of the DMBs branches in the South West geopolitical zone in Nigeria. The descriptive statistics, which involved the current levels of financial performance on deposit money banks showed an improvement in the return on assets due to the deployment of financial technology with the weighted average of 216 or 35.94% while more than 97% of respondents perceive the level of improvement in equities of banks in Nigeria as moderate followed by the rate of improvement in net income margin of banks with weighted mean of 192 or 31.9%. The empirical results showed that the deployment of automated teller machine, mobile banking, internet banking and point of sales on the financial performance of banks have significantly and positively improve banks’ return on asset, equity and the net income. This is an indication that the financial performance of Nigerian banks’ are highly sensitive to changes in the alternative banking channels as 1%, rises in automated teller machine increase the return on asset by 0.18%. In the same vein, increase in mobile banking to the tune of 1% raised the level of return on asset by 0.29%. Thus the study concludes that the deployment of mobile banking and internet bank drive virtually all the indicators of bank financial performance in Nigeria. However, the paper recommends that, the deployment of mobile banking was more pronounced, and particularly in the area of banks’ return on equity although all the alternative banking channels contributes to bank financial performance in Nigeria.
Spectrum on Non-Surgical Causes of Internal Jugular Vein Thrombosis In Otorhinolaryngology Practice
Authors: Mohamed Mohd Hazmi , Ishak Azlan Iskandar , Wan Sulaiman Wan Aliaa
Published: February 2024

Internal jugular vein thrombosis is an uncommon entity secondary to various aetiologies. In the pre-antibiotic era, it was commonly associated with Lemierre syndrome, a septic thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. With the advent of antibiotics, Lemierre syndrome has become a rare entity and is often overlooked. Internal jugular vein thrombosis may also occur in the setting of malignancy, a combination referred to as Trousseau’s syndrome, which is not well documented.
Laryngeal Sarcoma: A Case Report
Authors: Mohammad Nasir Zuraini , Ishak Azlan Iskandar , Ishak Noor Liza , Othman Noriah , Mohamad Doi Mohamad Doi
Published: February 2024

Laryngeal sarcoma is a rare malignant tumour and the diagnosis requires comprehensive histopathological and immunohistochemical examinations. Due to its rarity, there is paucity of information on its behaviour and management. We report a case of an elderly male presented with one month history of hoarseness. Laryngoscopic examination showed a large exophytic mass at anterior commissure causing partial airway obstruction. Tracheostomy, direct laryngoscopy and excision of tumour with adequate margin were performed. The histopathological examination revealed myofibroblastic sarcoma. Computed tomography of the neck showed no regional or distant metastasis. Post-operatively, he was decannulated and there was no clinical evidence of recurrence. Management of LS is highly individualised. Complete tumour excision with clear margins is the primary treatment. Neck dissection is not required if there is no nodal metastasis. Radiotherapy is advocated in selected cases to achieve loco-regional control.
Unilateral Parotid Gland Enlargement in Newborn: Is it Suppurative Parotitis?
Authors: Uthaya Kumar Seenu Reddy , Mahadzir Mazlinda , Chen Irise Hoi Khin
Published: February 2024

Acute neonatal suppurative parotitis (ANSP) is a rare disease and a novel illness affecting newborns and premature neonates are more likely to contract it. A unilateral parotid swelling and pus discharge from the Stensen’s duct is pathognomonic and sonography is the first line tool to supplement the diagnosis of parotitis. An appropriate parenteral antibiotic therapy and adequate hydration are the mainstays of treatment. Herein, we report a case of ANSP in a 12-day-old baby girl with a 48-hour history of left pre-auricular swelling where a complete resolution of disease was achieved post-treatment.
A justiça dos tributos
Authors: Taveira Torres Heleno
Published: February 2024

The historical evolution of equity points to changes in the criteria for evaluating tax justice. The use of individual assets and agricultural production in ancient times was replaced in the Middle Ages by a finalistic reason, the common good, to limit the power to tax. It was only in Absolutism, through the conception of the “reasons of the State”, with a progressive transition to presumed indicators of wealth and ability to pay, that tax collection was directed towards public spending. The transition from this concept to material justice, based on the taxpayer’s consent, involved the intricate application of ethical criteria, especially the theories of benefit and sacrifice. This work argues that tax justice is substantial and qualified by the principle of contributory capacity, which denotes the difficulty in applying taxes in an equitable manner based on philosophical conjectures or the causa impositinis. It is a fact that security, allied to freedom, is considered an essential value of law in free and just societies, perceived as a sub‑principle of justice, by providing legal stability. The importance of the principle of ability to pay does not, however, mean that it should be imported in a way that does not identify any analytical constitutional structure, which strongly links the legitimacy of taxation to the principles of functional and material equality, as well as to the determination of competences and fundamental rights. It is therefore essential that the Brazilian tax system represents a coherent organization of its own principles and rules around the concept of taxation and the advance towards material legal certainty.
Tratamiento del hipo crónico refractario. Revisión sistemática de la literatura y Presentación de un caso clínico tratado con modulación eléctrica.
Authors: Yepes Carlos Jaime , Zapata José Fernando , Arias José Hugo
Published: February 2024

Aun con su poca incidencia, el hipo crónico refractario presenta un desafío frente al diagnóstico etiológico que puede ser la clave para el tratamiento del mismo. Proponemos una revisión del diagnóstico y del tratamiento actual e igualmente una revisión sistemática de la literatura con los comparadores de manejo farmacológico vs neuromodulación eléctrica en sus diferentes modalidades. Finalmente se reporta un caso tratado con modulación eléctrica del nervio frénico.
Drone Detection and Identification Using Artificial Intelligence
Authors: Payal N. Bhagat  , Harish V. Dasarwar  , Muskan R. Sayyad  , Prof. Shubham D. Shelake
Published: February 2024

Autonomous drone detection systems offer a probable solution to overcoming the issue of potential drone misuse, such as drug smuggling, violating people’s privacy, etc. Detecting drones can be difficult, due to similar objects in the sky, such as airplanes and birds. The objective of the project is to evaluate state-of-the-art models and training strategies for drone detection
Overview of Medical Coding
Authors: Ashwini Gaikwad  , Akash Tattu  , Sandesh Panmand  , Rushikesh Gade  , Pravin Hadawale
Published: February 2024

Medical coding involves converting medical procedures, diagnoses, services, and equipment into alphanumeric codes. ICD codes are used to represent a patient's illness or injury, while CPT codes pertain to the services performed by healthcare providers for the patient. HCPCS level II codes are utilized for healthcare equipment and supplies. Each code comes with its own specific rules and guidelines, and they must be applied in a specific sequence. When billing for services, medical billers rely on the reported codes. Even a minor error can result in significant time spent identifying the source of mistakes and cause substantial delays in receiving payments. Medical coders from clinical data management team process these terms and perform medical coding. Medical coding is performed to categorize the medical terms reported appropriately so that they canbe analyzed/reviewed. This article describes process which is used for medical coding in clinical data management and two most commonly used medical dictionaries MedDRA and WHO-DDE in brief. It is expected to help medical coders to understand the process of medical coding in clinical data management. Few common issues which the medical coder faces while performing medical coding, are also highlighted.
BẤT THƯỜNG BÀO TƯƠNG NOÃN CÓ HẠT ẢNH HƯỞNG ĐẾN KẾT CỤC CỦA THỤ TINH TRONG ỐNG NGHIỆM
Authors: Nguyễn Minh Đức , Nguyễn Phan Cẩm Trang , Trịnh Hồng Thái , Nguyễn Đình Tảo
Published: February 2024

Mục tiêu: Nghiên cứu nhằm phân tích ảnh hưởng của bất thường bào tương noãn có hạt trung tâm (Centrally located cytoplasmic granular - CLCG) lên tỷ lệ thụ tinh, chất lượng phôi ngày 2 và kết cục thai sinh sống của chu kỳ có hình thái noãn trên. Phương pháp nghiên cứu: Nghiên cứu tiến cứu tiến hành trên 231 chu kỳ ICSI tại Bệnh viện Chuyên Khoa Nam học và Hiếm muộn Hà Nội từ năm 2016 đến 2019. Các chu kỳ đều sử dụng tinh trùng xuất tinh trong ngày chọc hút và chất lượng tinh trùng đạt tiêu chuẩn WHO 2010 với tỷ lệ hình dạng bình thường tối thiểu 1%. Tỷ lệ thụ tinh và chất lượng phôi ngày 2 được so sánh giữa 4 nhóm noãn CLCG gồm: có đúng một bất thường, có ít nhất một bất thường, có đúng hai bất thường và có ít nhất hai bất thường. Tỷ lệ em bé sinh sống được theo dõi ở 150 chu kỳ tuổi mẹ dưới 35 và số lượng noãn dưới 15. Kết quả: Tỷ lệ thụ tinh của nhóm có ít nhất một bất thường (72,1%), nhóm có ít nhất hai bất thường (69,5%) và nhóm có đúng hai bất thường (70,3%) thấp hơn có ý nghĩa thống kê so với các noãn không cùng đặc điểm lần lượt là 79,0%, 81,7% và 80,8% (p< 0,05). Tỷ lệ phôi tốt ngày 2 của nhóm có ít nhất một bất thường (53,8%), nhóm có ít nhất hai bất thường (57,3%) và nhóm có đúng hai bất thường (49,5%) thấp hơn có ý nghĩa thống kê so với các noãn không cùng đặc điểm lần lượt là 65,8%; 76,5%; và 75,1% (p< 0,05). Tỷ lệ thai sinh sống giữa các chu kỳ có bất thường CLCG và không có CLCG không có sự khác biệt có ý nghĩa thống kê (57,6% so với 44,0%, p>0,05). Kết luận: CLCG là một đặc điểm bất thường noãn làm giảm tỷ lệ thụ tinh và có xu hướng làm giảm tỷ lệ phôi tốt hai ngày tuổi, tuy nhiên, chưa xác định được ảnh hưởng đến kết cục có em bé sinh sống với nhóm bệnh nhân trẻ tuổi và ít noãn.
MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN HỘI CHỨNG CHÂN KHÔNG YÊN Ở BỆNH NHÂN ĐỘT QUỴ CHẢY MÁU NÃO
Authors: Đỗ Đức Thuần , Nguyễn Đức Thuận , Phạm Ngọc Thảo
Published: February 2024

Mục tiêu: Khảo sát một số yếu tố liên quan với hội chứng chân không yên ở bệnh nhân đột quỵ não chảy máu não. Phương pháp nghiên cứu: nghiên cứu tiến cứu tại khoa Đột quỵ, Bệnh viện Quân y 103 từ tháng 9 năm 2022 đến tháng 9 năm 2023. Kết quả nghiên cứu: với 186 bệnh nhân đột quỵ chảy máu não có tỷ lệ RLS là 8,6% ở thời điểm 31 ± 7,6 ngày. hút thuốc lá, tiền sử gia đình có người thân cấp 1 bị RLS, BMI và điểm NIHSS cao, chảy máu vùng hạch nền liên quan đến RLS sau đột quỵ. Trong đó có BMI trung bình trên 22,12±2,10 (OR: 1,279; 95%CI: 1,028-1,590; p =0,027) và đột quỵ chảy máu hạch nền (OR: 2,734; 95%CI: 1.669-11,164; p =0,038) có liên quan độc lập với RLS sau đột quỵ. Kết luận: RLS gặp ở 8,6% sau đột quỵ chảy máu não. Hút thuốc lá, có người thân bị RLS, BMI cao, tổn thương vùng hạch nền liên quan RLS sau đột quỵ. Trong đó BMI cao và tổn thương hạch nền có mối liên quan độc lập với RLS
NGHIÊN CỨU PHÁT HIỆN ĐỘT BIẾN TẠI VÙNG KHỞI ĐỘNG GEN TERT Ở BỆNH NHÂN U THẦN KINH ĐỆM BẰNG GIẢI TRÌNH TỰ SANGER
Authors: Lương Bắc An , Hồ Quốc Chương , Dương Bích Trâm , Hoàng Anh Vũ , Trần Kim Tuyến
Published: February 2024

Mở đầu: U thần kinh đệm là một trong các ung thư có tỉ lệ tử vong cao, chiếm tới hơn 40% các trường hợp u não nguyên phát. Đột biến vùng khởi động phiên mã ngược gen telomerase (pTERT), C228T và C250T, thường gặp ở nhiều loại ung thư khác, trong đó có u thần kinh đệm. Các đột biến này tạo vị trí gắn kết ETS1 mới, làm tăng biểu hiện của enzyme telomerase trực tiếp dẫn đến quá trình sinh ung. Hiện diện đột biến gen pTERT kết hợp với các dấu ấn sinh học khác như đột biến gen IDH, 1p19q, TP53, EGFR giúp phân loại nhóm bệnh u thần kinh đệm. Sàng lọc đột biến gen pTERT giúp đưa ra phác đồ điều trị phù hợp với tiên lượng điều trị tốt hơn. Mục tiêu: Xác định đột biến trên vùng khởi động gen TERT ở bệnh nhân u thần kinh đệm bằng kĩ thuật giải trình tự Sanger. Phương pháp: Nghiên cứu mô tả cắt ngang với 83 mẫu mô vùi nến của bệnh nhân được chẩn đoán mắc u thần kinh đệm. Sử dụng kĩ thuật giải trình tự Sanger phát hiện đột biến C228T và C250T thuộc vùng khởi động gen TERT. Kết quả: Phát hiện 27/83 (32,53%) bệnh nhân mang đột biến tại vùng gen pTERT. Trong đó, 17/83 (20,48%) trường hợp mang đột biến C228T và 10/83 (12,05%) trường hợp mang đột biến C250T. Kết luận: Nghiên cứu bước đầu mô tả được tỉ lệ mang đột biến tại vùng gen pTERT ở bệnh nhân u thần kinh đệm tại Việt Nam.
TỈ LỆ MẮC BỆNH VÀ MỘT SỐ YẾU TỐ LIÊN QUAN CỦA BỆNH NẤM NÔNG TRÊN CÁC BỆNH NHÂN ĐẾN KHÁM TẠI BỆNH VIỆN DA LIỄU TRUNG ƯƠNG TRONG GIAI ĐOẠN 2017-2019
Authors: Trần Cẩm Vân , Nguyễn Hữu Sáu
Published: February 2024

Mục tiêu: xác định tỉ lệ mắc bệnh và các yếu tố liên quan của bệnh nấm nông trên các bệnh nhân đến khám tại bệnh viện da liễu trung ương. Phương pháp nghiên cứu: mô tả cắt ngang trên các bệnh nhân có biểu hiện lâm sàng nghi ngờ nhiễm nấm nông đến khám tại bệnh viện da liễu trung ương trong giai đoạn từ tháng 1/2017 đến tháng 12/2019. Kết quả: Tỉ lệ bệnh nhân có soi tươi dương tính với nấm là 14,75%, trong đó nấm Dermatophyte chiếm tỉ lệ cao nhất với 69,3%. Đứng thứ hai là nấm Malssezia với tỉ lệ 25,3%, còn lại là nấm Candida với tỉ lệ 5,5%. Định danh đến mức độ loài cho thấy T. rubrum, T. mentagrophytes, M. glabrata và C. albican là các chủng nấm hay gặp nhất. Tỉ lệ mắc bệnh nấm nông gặp ở nam nhiều hơn nữ. Độ tuổi có tỉ lệ mắc bệnh cao nhất là từ 20 – 29 tuổi. Bệnh có xu hướng gia tăng nhiều nhất vào khoảng tháng 3–4 và tháng 8-9. Kết luận: Nhiễm nấm nông là một bệnh rất thường gặp với tỉ lệ 14,75%, gặp ở nam nhiều hơn nữ, trong nhóm tuổi từ 20-29, có xu hướng gặp nhiều vào tháng 3,4 và tháng 8,9. Căn nguyên thường gặp là nhiễm nấm Dermatophytes với chủng T. rubrum và T. mentagrophytes.