bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 4 from A Systems Biology Approach Identifies Effective Tumor–Stroma Common Targets for Oral Squamous Cell Carcinoma
Authors: Meng Wenxia , Wu Yun , He Xin , Liu Chuanxia , Gao Qinghong , Ge Lin , Wu Lanyan , Liu Ying , Guo Yiqing , Li Xiaoyu , Liu Yurong , Chen Sixiu , Kong Xiangli , Liang Zhi , Zhou Hongmei
Published: April 2023

PDF file - 1150K, From cancer signature genes to EMCT seed predictions (S1); Immunohistochemistry was used to distinguish NFs and CAFs with antibodies targeting cytokeratin (CK), vimentin (VIM), and alpha-smooth muscle actin (alpha-SMA) (x100) (S2); Expression of TbetaRIII in OSCC cells and CAFs after retroviral transfection (S3); Examination of TbetaRIII and vimentin expression in sections of different types of HSC-2 tumors (S4).
Supplementary Figures 1-3 from Extracellular RNA Liberates Tumor Necrosis Factor-α to Promote Tumor Cell Trafficking and Progression
Authors: Fischer Silvia , Gesierich Sabine , Griemert Barbara , Schänzer Anne , Acker Till , Augustin Hellmut G. , Olsson Anna-Karin , Preissner Klaus T.
Published: April 2023

PDF-180K, Supplementary Figure 1: Adhesion of tumor cells to endothelial cells by partly degraded eRNA. Supplementary Figure 2: eRNA-induced adhesion of tumor cells. Supplementary Figure 3: eRNA-mediated adhesion and transmigration of mouse fibrosarcoma cells.
Supplementary Movie Legends from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

PDF file - 58KB
Supplementary Movie 6 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

AVI file - 481KB, Dynamics of ARv7 variant nuclear accumulation in cells treated with 1nM TXT.
Supplementary Figure 3 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: April 2023

PDF file - 2248KB, Cdk1 phosphorylation of YAP is essential for Taxol-induced disruption of YAP-TEAD interaction.
Supplementary Figure Legends from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

PDF file - 50KB
Supplementary Figure Legends from NUP98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint
Authors: Salsi Valentina , Ferrari Silvia , Gorello Paolo , Fantini Sebastian , Chiavolelli Francesca , Mecucci Cristina , Zappavigna Vincenzo
Published: April 2023

PDF - 77K, Legends to Supplementary Figures
Supplementary Figure 2 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

PDF file - 39K, Correlation between the expression level of ADAR1 and the editing level of AZIN1 (left panel) or FLNB (right panel) among nine ESCC cell lines.
Supplemental Figure S4 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

A, Western blot analyses showing expression of AZIN1 protein in the indicated cell lines. beta-actin was the loading control. B, Quantification of cells from the indicated cells that migrated through the PET-membrane or invaded through the Matrigel-coated membrane.
SSupplementary Tables 1 - 2 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

PDF file - 75K, IHC scores of ADAR1 in 136 matched pairs of primary ESCCs and (NT) tissues (S1); The positive correlation between the tumoral overexpression of ADAR1 and tumoral genomic amplification of ADAR1 (S2).
Supplementary Methods from Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Authors: Gopal Y.N. Vashisht , Rizos Helen , Chen Guo , Deng Wanleng , Frederick Dennie T. , Cooper Zachary A. , Scolyer Richard A. , Pupo Gulietta , Komurov Kakajan , Sehgal Vasudha , Zhang Jiexin , Patel Lalit , Pereira Cristiano G. , Broom Bradley M. , Mills Gordon B. , Ram Prahlad , Smith Paul D. , Wargo Jennifer A. , Long Georgina V. , Davies Michael A.
Published: April 2023

Supplementary Methods. This file contains detailed descriptions of some of the methods used for performing the experiments.
Supplementary Figure 2 from BRG1/SMARCA4 Inactivation Promotes Non–Small Cell Lung Cancer Aggressiveness by Altering Chromatin Organization
Authors: Orvis Tess , Hepperla Austin , Walter Vonn , Song Shujie , Simon Jeremy , Parker Joel , Wilkerson Matthew D. , Desai Nisarg , Major Michael B. , Hayes D. Neil , Davis Ian J. , Weissman Bernard
Published: April 2023

Supplementary Figure 2. This figure shows additional characterization of global nucleosomal positioning changes in Brg1 KD cell lines.
Supplementary Figure Legends from Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus
Authors: Zemp Franz J. , McKenzie Brienne A. , Lun Xueqing , Reilly Karlyne M. , McFadden Grant , Yong V. Wee , Forsyth Peter A.
Published: April 2023

Legend for Supplementary Figures S1-S10.
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: April 2023

Expanded methods description
Supplementary Figure S4 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: April 2023

Supplemental Figures S4A,B,C,D: Primary tumor growth kinteics and size distribution of 4T1 lung metastases of CT26 (s.c.) and 4T1 (o.t.) tumors. Figure S4A: Tumor volume of CT26 (s.c.) tumors in the neck area. Figure S4B: Tumor volume of 4T1 (o.t.) tumors in the mammary gland as determined by sonography. Figure S4C,D: Size distribution of lung metastases of 4T1 tumors on day 25.
Supplementary Figure 4 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 61K, Luciferase assays the effect of miR-22 on Sp3 and Sp4 post-transcriptional regulation.
Supplementary Table 2 from The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
Authors: Raha Debasish , Wilson Timothy R. , Peng Jing , Peterson David , Yue Peng , Evangelista Marie , Wilson Catherine , Merchant Mark , Settleman Jeff
Published: April 2023

XLSX file - 42KB, Statistical analysis of xenograft tumor data.
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: April 2023

Fig. S1. Supplementary data for large scale genomic aberrations illustrated in Figure 2, including: A) the distribution of mapped read density of WGS; B) PCR confirmation of translocation and fusion junctions of a superamplicon; and C) PCR and RT-PCR amplification of MGAM, ZFAND3, and the ZFAND3-MGAM fusion gene. Fig. S2. The distribution of mapped read density of WES, supplementary data for Figure 3. Fig. S3. Differentially expressed genes and functions among complex, simple carcinomas and normal mammary glands, supplementary data for Figure 3. Fig. S4. IHC images of histone modifications in canine normal mammary glands at 400X magnification, supplementary data for Figure 4. Fig. S5. IHC images of histone modifications in simple carcinomas, complex carcinomas and normal mammary glands at 200X magnification, supplementary data for Figure 5. Fig. S6. Supplementary data for homology between canine MCs and human breast cancers described in Figure 6. These include differentially expressed genes between ER+ and ER- carcinomas at FDR â‰¤ 0.1 and an example of PAM50 clustering indicating canine and human tumor IDs.
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: April 2023

Supplementary Table S2. Supplementary data for CNA discovery in canine MCs by aCGH and WGS analyses, including CNA result summary, amplified/deleted gene list and chimeric sequence reads related to the superamplicon.
Supplementary Table 2 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: April 2023

XLSX file - 40K, Canine genes identified by Ingenuity Pathway Analysis as part of the NF-kB or B-cell receptor signaling pathways (Fig. 5).
Supplementary Methods and Figure Legends from Mycoplasma Hyorhinis Infection Promotes NF-κB–Dependent Migration of Gastric Cancer Cells
Authors: Duan Hongying , Chen Ling , Qu Like , Yang Hua , Song Sonya Wei , Han Yong , Ye Meihua , Chen Wanyuan , He Xianglei , Shou Chengchao
Published: April 2023

Supplementary Methods and Figure Legends from Mycoplasma Hyorhinis Infection Promotes NF-κB–Dependent Migration of Gastric Cancer Cells
Supplemental Figures S1-S5 from Novel Paracrine Modulation of Notch–DLL4 Signaling by Fibulin-3 Promotes Angiogenesis in High-Grade Gliomas
Authors: Nandhu Mohan S. , Hu Bin , Cole Susan E. , Erdreich-Epstein Anat , Rodriguez-Gil Diego J. , Viapiano Mariano S.
Published: April 2023

Fibulin-3 and DLL4 expression in human brain microvascular endothelial cells (S1); Expression of endothelial fibulin-3 is not induced by glioma cells (S2); Fibulin-3 increases glioma cell association with endothelial tubules (S3); Knockdown of fibulin-3 reduces expression of Notch-dependent genes in endothelial cells (S4); Fibulin-3 associates with secreted TIMP-3 (S5).
Supplemental Figure and Movie Legend from Novel Paracrine Modulation of Notch–DLL4 Signaling by Fibulin-3 Promotes Angiogenesis in High-Grade Gliomas
Authors: Nandhu Mohan S. , Hu Bin , Cole Susan E. , Erdreich-Epstein Anat , Rodriguez-Gil Diego J. , Viapiano Mariano S.
Published: April 2023

Legends for Supplemental Figures S1-S5 and Supplemental Movie S1.
Data Supplement from Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks
Authors: Colvin Teresa A. , Gabai Vladimir L. , Gong Jianlin , Calderwood Stuart K. , Li Hu , Gummuluru Suryaram , Matchuk Olga N. , Smirnova Svetlana G. , Orlova Nina V. , Zamulaeva Irina A. , Garcia-Marcos Mikel , Li Xiaokai , Young Z.T. , Rauch Jennifer N. , Gestwicki Jason E. , Takayama Shinichi , Sherman Michael Y.
Published: April 2023

Supplemental Table S1. Microarray data on effetcs of Hsp70 depletion in MCF7 cells.
Supplementary Figure S6 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

Effect of PRMT7 on HDAC3 protein expression and location.
Data Supplement from Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks
Authors: Colvin Teresa A. , Gabai Vladimir L. , Gong Jianlin , Calderwood Stuart K. , Li Hu , Gummuluru Suryaram , Matchuk Olga N. , Smirnova Svetlana G. , Orlova Nina V. , Zamulaeva Irina A. , Garcia-Marcos Mikel , Li Xiaokai , Young Z.T. , Rauch Jennifer N. , Gestwicki Jason E. , Takayama Shinichi , Sherman Michael Y.
Published: April 2023

Supplemental Figure S4. Treatment with YM-1 affects p21 and surviving in tumor xenografts.
Supplementary Figures 1 - 3 from Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells
Authors: Chen Jiangzhi , Xu Hong , Zou Xiuqun , Wang Jiamin , Zhu Yi , Chen Hao , Shen Baiyong , Deng Xiaxing , Zhou Aiwu , Chin Y. Eugene , Rauscher Frank J. , Peng Chenghong , Hou Zhaoyuan
Published: April 2023

PDF file - 329K, Supplementary Figure 1: Mutation of Ring domains of Ring1A/B proteins does not change their subcellular localization. Supplementary Figure 2: qRT-PCR analysis of the known PRC1 target genes HOXC5 and HOXB4 and Snail target gene Cyclin D2 in PanC1-shLuc and PanC1-shRing1A/B cells. Supplementary Figure 3: Simultaneous depletion of Ring1A and Ring1B results in global decrease of H2AK119 monoubiquitination, and Snail loss of repression on E-cadherin in AsPC1 cells.
Data Supplement from NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis
Authors: Weaver Kelly L. , Alves-Guerra Marie-Clotilde , Jin Ke , Wang Zhiqiang , Han Xiaoqing , Ranganathan Prathibha , Zhu Xiaoxia , DaSilva Thiago , Liu Wei , Ratti Francesca , Demarest Renee M. , Tzimas Cristos , Rice Meghan , Carpio Rodrigo Vasquez-Del , Dahmane Nadia , Robbins David J. , Capobianco Anthony J.
Published: April 2023

Supplemental Figure S1. NACK is a novel Notch-interacting protein.
Supplementary Figure S2 from Oncogenic Properties of a Spermatogenic Meiotic Variant of Fer Kinase Expressed in Somatic Cells
Authors: Yaffe Etai , Hikri Elad , Elkis Yoav , Cohen Ortal , Segal Ariela , Makovski Adar , Varvak Alexander , Shpungin Sally , Nir Uri
Published: April 2023

Supplementary Figure S2: demonstrates the different tumor formation promoting activities of mitochondrial directed and undirected FerT in immuno-compromised mice
Supplementary Data Legends from Oncogenic Properties of a Spermatogenic Meiotic Variant of Fer Kinase Expressed in Somatic Cells
Authors: Yaffe Etai , Hikri Elad , Elkis Yoav , Cohen Ortal , Segal Ariela , Makovski Adar , Varvak Alexander , Shpungin Sally , Nir Uri
Published: April 2023

Supplementary Data legends. This File contains the legends for the supplementary Figures and tables
Supplementary Figure 3 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 179KB, Supplementary Figure S3. ALK regulates tyrosine-phosphorylation of FLOT1.
Supplementary Figure Legends from Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
Authors: Textor Ana , Listopad Joanna J. , Wührmann Lara Le , Perez Cynthia , Kruschinski Anna , Chmielewski Markus , Abken Hinrich , Blankenstein Thomas , Charo Jehad
Published: April 2023

Supplementary Figure Legends (1-5)
Supplementary Figure S7 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S7. Kaplan-Meier survival curve as in Figure 4D and E, but now applying a second publically available dataset of ERα-positive breast cancer patients treated with adjuvant tamoxifen.
Supplementary Figure S5 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S5. Contingency table displaying the number of genes that exhibit higher or lower expression in the patients with good outcome as compared to poor outcome patients.
Supplementary Figure S4 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S4. Pathway analyses of the largest gene subclusters identified through hierarchical clustering.
Supplementary Figure 3 from miR326 Maturation Is Crucial for VEGF-C–Driven Cortactin Expression and Esophageal Cancer Progression
Authors: Hong Chih-Chen , Chen Pai-Sheng , Chiou Jean , Chiu Ching-Feng , Yang Ching-Yao , Hsiao Michael , Chang Yi-Wen , Yu Yang-Hao , Hung Mien-Chie , Hsu Nai-Wen , Shiah Shine-Gwo , Hsu Nan-Yung , Su Jen-Liang
Published: April 2023

Supplementary Figure 3. The mRNA expression of CTTN in rhVEGF-C-treated TE-1 cells. TE-1 cells were treated with a various doses of rhVEGF-C (0, 25, 50, 100 and 200 ng/mL) for 24 hours and isolated total RNA to measure the expression level of CTTN by RT-PCR. GAPDH was used as an internal control.
Supplementary Methods, Figures 1 - 8 from Hypoxia Promotes Nuclear Translocation and Transcriptional Function in the Oncogenic Tyrosine Kinase RON
Authors: Chang Hong-Yi , Liu Hsiao-Sheng , Lai Ming-Derg , Tsai Yuh-Shyan , Tzai Tzong-Shin , Cheng Hong-Ling , Chow Nan-Haw
Published: April 2023

PDF file - 2581K, Supplementary Figure 1 - Expression pattern of RON in human uroepithelial cell lines and subcellular distribution of RON in hepatocellular and colon cancer cells. Supplementary Figure 2 - Nuclear translocation of RON and its interaction with HIF-1alpha examined by different antibodies to human RON. Supplementary Figure 3 - Graphical representation of the RON functional domain truncation mutant constructs. Supplementary Figure 4 - Transactivation of c-jun promoter activity by nuclear RON and HIF-1alpha complex. Supplementary Figure 5 - Graphical representation of putative binding sites for nuclear RON in the c-jun promoter. Supplementary Figure 6 - The importance of tyrosine kinase activity for interaction of nuclear RON with HIF-1alpha and c-jun transcriptional activation. Supplementary Figure 7 - The binding of RON deletion mutants to c-jun promoter in J82 stable cell lines. Supplementary Figure 8 - Immunohistochemical staining of RON and HIF-1alpha in primary human bladder cancer.
Supplementary Video 1 from NGF Blockade at Early Times during Bone Cancer Development Attenuates Bone Destruction and Increases Limb Use
Authors: McCaffrey Gwen , Thompson Michelle L. , Majuta Lisa , Fealk Michelle N. , Chartier Stephane , Longo Geraldine , Mantyh Patrick W.
Published: April 2023

This film depicts the nocifensive behavior of a naÃƒÂ¯ve mouse. During the film, when the mouse is stationary, the toes of the left foot are spread out and a range of brightness appears on the bottom of the foot because it is bearing weight on the wire floor. Therefore it is distributing its weight evenly across its hind limbs. Time spent in this position would not be counted as nocifensive behavior. When the mouse moves about the enclosure, weight bearing is evident for the left hind limb since the foot has variation in its brightness and spread out toes that firmly rest on the wire cage floor during each step. Time spent in this behavior would not be counted as nocifensive behavior.
Supplementary Figure 3 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

PDF - 273K, A) Inhibition of OGT expression with siRNA reduces the levels of c-Myc in LNCaP cells. B) Wheat germ agglutinin (WGA) lectin was used to enrich proteins modified with O-linked glycosylation in prostate cancer cells. C) Immunoprecipitation of O-GlcNAc modified proteins with a monoclonal antibody RL2.
Supplementary Figure 2 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

PDF - 305K, Correlation between the expression of OGT and candidate transcription factors in localized prostate cancer.
Supplementary Video #8 from Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
Authors: Wong Andrew D. , Searson Peter C.
Published: April 2023

Angiogenic sprouts and neighboring HMVECs oscillating in position relative to a cluster of MDA-MB-231 breast cancer cells.
Supplementary Figures 1 - 2, Methods, Legends from Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
Authors: Wong Andrew D. , Searson Peter C.
Published: April 2023

Supplementary video legends; supplementary Figures S1 and S2; supplementary experimental procedures. Supplementary Figure S1. 3D projection from above and side of a confocal z-stack. Supplementary Figure S2. A, Time lapse images of an intravasating tumor cell.
Figure S2 Inhibition of mTORC1 and glutamate cysteine ligase induces cytotoxicity in Tsc2-/- MEFs from mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress
Authors: Li Jing , Shin Sejeong , Sun Yang , Yoon Sang-Oh , Li Chenggang , Zhang Erik , Yu Jane , Zhang Jianming , Blenis John
Published: April 2023

Cell viability of Tsc2-/- MEFs and WT MEFs treated with single agent and combination; siRNA-mediated knockdown of GCLC with or without rapamycin; cell viability of ELT3-V3 cells. Cell death study of ELT3-V3 vs. ELT3-T3 and 621-102 vs. 621-103
Supplementary Figures S1-S8 from Adverse Immunoregulatory Effects of 5FU and CPT11 Chemotherapy on Myeloid-Derived Suppressor Cells and Colorectal Cancer Outcomes
Authors: Kanterman Julia , Sade-Feldman Moshe , Biton Moshe , Ish-Shalom Eliran , Lasry Audrey , Goldshtein Aviya , Hubert Ayala , Baniyash Michal
Published: April 2023

5FU and CPT11 display opposite effects on β-catenin localization in CRC colons (S1); 5FU and CPT11 display opposite effects on MDSC accumulation and CD247 expression in the colons of CRC-mice (S2); 5FU or CPT11 chemotherapies do not alter the elevated Treg levels in spleens from CRC-mice (S3); A combined 5FU and CPT11 therapy preserves immunosuppression (S4); A schematic representation of mouse model for CRC in which MDSCs were in vivo depleted in CPT11 treated mice by Gr1 mAb administration every 3 days (S5); 5FU and CPT11 differently affect monocytic/granulocytic MDSC sensitivity to apoptosis (S6); 5FU and CPT11 treatments display opposite effects on mRNA expression levels of pro-inflammatory molecules (S7); 5FU and CPT11 treatments differently affect the immunological profile of mice exhibiting a pathology free chronic inflammation (S8).
Table S2 from Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
Authors: Tao Shasha , Wang Shue , Moghaddam Seyed Javad , Ooi Aikseng , Chapman Eli , Wong Pak K. , Zhang Donna D.
Published: April 2023

Table S2. The percentage of mice with adenocarcinomas from each group.
Supplemental Figures S1-S8 from AEG-1 Promoter–Mediated Imaging of Prostate Cancer
Authors: Bhatnagar Akrita , Wang Yuchuan , Mease Ronnie C. , Gabrielson Matthew , Sysa Polina , Minn Il , Green Gilbert , Simmons Brian , Gabrielson Kathleen , Sarkar Siddik , Fisher Paul B. , Pomper Martin G.
Published: April 2023

S1: Schematic maps of AEG-Prom and PEG-Prom reporter constructs S2: c-MYC protein levels analyzed in prostate cancer cell lines by western blotting using anti-MYC antibody (57-70 kDa) S3: Time course for model maturation with PC3-ML-Luc cells using bioluminescence imaging (BLI) at week 5 after injection of: (A) 5 x 104 cells (intracardiac); (B) 1 x 106 cells (tail vein) S4: Cancer-specific AEG-Prom and PEG-Prom activity shown by bioluminescence imaging (BLI) in an experimental model of human prostate cancer (PC3-ML) S5: Comparison of Luc plasmid delivery to lungs of the PCa group for pAEG-Luc treated and pPEG-Luc treated animals (n = 3, PCa-1-3 in Supplemental Fig. S4), respectively S6: Correlation between AEG-1 promoter-driven Luc expression and metastatic sites by histopathological analysis in a bone metastatic prostate cancer model of prostate cancer metastasis S7: Cancer-Specific AEG-Prom activity shown by bioluminescence imaging (BLI) in experimental models of human prostate cancer (PC3-ML) S8: AEG-Prom-based SPECT/CT imaging detects distant metastasis not identified by NaF- or FDG-PET/CT
Supplemental Figures 1 - 5 from Myeloid IKKβ Promotes Antitumor Immunity by Modulating CCL11 and the Innate Immune Response
Authors: Yang Jinming , Hawkins Oriana E. , Barham Whitney , Gilchuk Pavlo , Boothby Mark , Ayers Gregory D. , Joyce Sebastian , Karin Michael , Yull Fiona E. , Richmond Ann
Published: April 2023

Figure S1: Myeloid Ikkβ is required for anti-tumorigenic immunity. Figure S2. Myeloid cell depletion alters tumor immunity. Figure S3. Ikkβ loss alters macrophage phagocytosis capacity. Figure S4. Myeloid Ikkβ deletion reduced the cytotoxicity of T cells Figure S5. Cytokines play a major role in orchestrating the cellular make-up of the tumor microenvironment.
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Figure S2. Ad5ÃŽ?24 does not increase the effector function of GD2.CAR-T cells
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Legends. Legends for Supplementary Figures, Tables and Movies.
Supplementary Script A from Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery
Authors: Hudson Andrew M. , Yates Tim , Li Yaoyong , Trotter Eleanor W. , Fawdar Shameem , Chapman Phil , Lorigan Paul , Biankin Andrew , Miller Crispin J. , Brognard John
Published: April 2023

Groovy program script used to make the 18 cell line comparison
Supplementary Figures 1 - 5 from Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery
Authors: Hudson Andrew M. , Yates Tim , Li Yaoyong , Trotter Eleanor W. , Fawdar Shameem , Chapman Phil , Lorigan Paul , Biankin Andrew , Miller Crispin J. , Brognard John
Published: April 2023

Supplementary Figure 1. Original comparison of 18 cell lines sequenced by COSMIC and CCLE to display that the conformity of missense mutation detection ranges from 56.75% in HCC2218 cell line to 12.90% in HCC1954. Supplementary Figure 2. Bamfile images of the CRUK MI sequencing shows good read coverage with the PAK4 p.E119Q mutation in 51% of reads compared to CCLE hybrid capture bamfiles of the same area with only 2 reads and neither read showing a mutation. Supplementary Figure 3. Western Blot showing empty vector, PAK4 wildtype, and p.E119Q mutant overexpression in 293T cells with the mutant showing enhanced ERK phosphorylation but no effect on JNK phosphorylation. Supplementary Figure 4. Chart demonstrating an increase in conformity of reported mutations when the CCLE data that has not been filtered for germ line SNPs is used. Supplementary Figure 5. Comparison of mutation detection in four cell lines between COSMIC, CCLE and our own institute (CRUK MI) reveals 29.41% of mutations are missed by CRUK MI but the discrepancy decreases to 17.65% when the comparison is repeated with CRUK MI data that has not been filtered for germ line SNPs.
Supplementary Figure S1 from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: April 2023

Supplementary Figure S1. AMO-1 cells and NCI-H929 cells were seeded at 2 x 105 cells/ml on day 0, and were treated either by BX-912 or AR12 at their concentrations of 5, 10, or 20 microM for 24, 48, and 72 hours. Cells were directly stained by trypan blue, and viable cell numbers were counted under the inverted microscope. Results were mean{plus minus}SD of triplicate analyses.
Supplementary Table S7 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

Top 5% of mutated genes based on the proportion of affected samples in CRC cell lines and TCGA-analyzed primary cancers for non-hypermutated and hypermutated MSI-H samples.
Supplementary Table 1 from The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Authors: Izumchenko Evgeny , Chang Xiaofei , Michailidi Christina , Kagohara Luciane , Ravi Rajani , Paz Keren , Brait Mariana , Hoque Mohammad O. , Ling Shizhang , Bedi Atul , Sidransky David
Published: April 2023

PDF file - 2202KB, Summary of EGFR, KRAS, NRAS and P53 mutation status in 18 human NSCLCs and 27 pancreatic directly xenografted low passage tumors.
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Figure S2. An shRNA-resistant FAT10 plasmid rescues the expression of HOXB9 and recovers the cell migration and invasion phenotype in shFAT10 HCC cells.
Supplementary Methods and References from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Materials and Methods from PCTAIRE1 Phosphorylates p27 and Regulates Mitosis in Cancer Cells
Authors: Yanagi Teruki , Krajewska Maryla , Matsuzawa Shu-ichi , Reed John C.
Published: April 2023

Supplementary Materials and Methods. Primers for quantitative RT-PCR. In vitro kinase assays. Time-lapse microscopy. Patient specimens. Gene expression. Statistical Analysis.
Supplementary Methods and References from Targeting the c-Met/FZD8 Signaling Axis Eliminates Patient-Derived Cancer Stem–like Cells in Head and Neck Squamous Carcinomas
Authors: Sun Shuyang , Liu Suling , Duan Sheng Zhong , Zhang Lei , Zhou Henghua , Hu Yongjie , Zhou Xianghui , Shi Chaoji , Zhou Rong , Zhang Zhiyuan
Published: April 2023

Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.
Data Supplement from Novel Drug Candidates for the Treatment of Metastatic Colorectal Cancer through Global Inverse Gene-Expression Profiling
Authors: van Noort Vera , Schölch Sebastian , Iskar Murat , Zeller Georg , Ostertag Kristina , Schweitzer Christine , Werner Kristin , Weitz Jürgen , Koch Moritz , Bork Peer
Published: April 2023

Supplementary Table S2. Drug-disease relations.
Supplementary Figure S1 from IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress
Authors: Shimizu Takatsune , Sugihara Eiji , Yamaguchi-Iwai Sayaka , Tamaki Sakura , Koyama Yuko , Kamel Walied , Ueki Arisa , Ishikawa Tomoki , Chiyoda Tatsuyuki , Osuka Satoru , Onishi Nobuyuki , Ikeda Hiroko , Kamei Junzo , Matsuo Koichi , Fukuchi Yumi , Nagai Toshihiro , Toguchida Junya , Toyama Yoshiaki , Muto Akihiro , Saya Hideyuki
Published: April 2023

Supplementary Figure S1: (A) Real-time PCR analysis of Igf1 expression in AXT cell-derived subcutaneous tumors. (B) Serum IGF2 concentration of control and tumor bearing mice with or without chemotherapy. (C) U2OS cells cultured under serum free or in the presence of IGF2. (D,E) Schemes of assays for cell viability (D) and RNA interference (E).
Supplementary Figure S5 from Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
Authors: Zhao Yu , Li Hang , Zhang Yingyi , Li Leilei , Fang Runping , Li Yinghui , Liu Qian , Zhang Weiying , Qiu Liyan , Liu Fabao , Zhang Xiaodong , Ye Lihong
Published: April 2023

CoRNR motif of HBXIP is required for co-activation of LXRs in a ligand-independent manner.
Supplementary Table from Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor Progression
Authors: Oh Ah-Young , Jung Youn Sang , Kim Jiseon , Lee Jee-Hyun , Cho Jung-Hyun , Chun Ho-Young , Park Soyoung , Park Hyunchul , Lim Sikeun , Ha Nam-Chul , Park Jong Sook , Park Choon-Sik , Song Gyu-Yong , Park Bum-Joon
Published: April 2023

Table S1. Clino-pathological information of human samples.
Supplementary Table S4 from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Table S4. Univariable and multivariable Cox regression analysis of survival prediction.
Figure S6 from RABL6A Promotes G1–S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner
Authors: Hagen Jussara , Muniz Viviane P. , Falls Kelly C. , Reed Sara M. , Taghiyev Agshin F. , Quelle Frederick W. , Gourronc Francoise A. , Klingelhutz Aloysius J. , Major Heather J. , Askeland Ryan W. , Sherman Scott K. , O'Dorisio Thomas M. , Bellizzi Andrew M. , Howe James R. , Darbro Benjamin W. , Quelle Dawn E.
Published: April 2023

Figure S6. Down-regulation of p27 in arrested RABL6A knockdown cells promotes S phase entry.
Supplemental Figure S3 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

Loss of Zfx does not affect normal cerebellar growth.
Supplemental Dataset S1 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

List of genes matching ZFX expression pattern in DAOY human MB cells following ZFX shRNA knockdown.
Figure S1 from RABL6A Promotes G1–S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner
Authors: Hagen Jussara , Muniz Viviane P. , Falls Kelly C. , Reed Sara M. , Taghiyev Agshin F. , Quelle Frederick W. , Gourronc Francoise A. , Klingelhutz Aloysius J. , Major Heather J. , Askeland Ryan W. , Sherman Scott K. , O'Dorisio Thomas M. , Bellizzi Andrew M. , Howe James R. , Darbro Benjamin W. , Quelle Dawn E.
Published: April 2023

Figure S1. Quantitative PCR measurement of human RABL6A DNA copy number in human PNET patient samples.
Supplementary Figures 1 - 15 from MicroRNA100 Inhibits Self-Renewal of Breast Cancer Stem–like Cells and Breast Tumor Development
Authors: Deng Lu , Shang Li , Bai Shoumin , Chen Ji , He Xueyan , Martin-Trevino Rachel , Chen Shanshan , Li Xiao-yan , Meng Xiaojie , Yu Bin , Wang Xiaolin , Liu Yajing , McDermott Sean P. , Ariazi Alexa E. , Ginestier Christophe , Ibarra Ingrid , Ke Jia , Luther Tahra , Clouthier Shawn G. , Xu Liang , Shan Ge , Song Erwei , Yao Herui , Hannon Gregory J. , Weiss Stephen J. , Wicha Max S. , Liu Suling
Published: April 2023

Figure S1. Comparison of ALDH-positive population in different breast cancer cell lines and primary xenografts (UM2, MC1, UM1). Figure S2. mir-100 overexpression decreases ki67+ population in vitro. Figure S3. mir-100 overexpression inhibits the proliferation of both ALDH+ population and ALDH- population. Figure S4. mir-100 inhibits tumor growth of SUM149, MCF7 and T47D in NOD/SCID mice. Figure S5. mir-100 expression is higher in the tumor cells from mir-100 group compared to that from CTRL group. Figure S6. The percentage of ALDH+ cells in both primary CTRL and secondary CTRL tumors were increased compared to the parental cells injected. Figure S7. mir-100 expression is higher in the tumor cells from mir-100 induction groups with DOX (Late and Early) compared to that from CTRL group. Figure S8. mir-100 overexpression is necessary to maintain the inhibition of SUM159 tumor growth in NOD/SCID mice. Figure S9. mir-100 knockdown increases tumor growth in vivo. Figure S10. mir-100 inhibits metastasis of Both Total (Unseparated) and ALDH+ SUM159 cells in vivo. Figure S11. Identification of direct targets of mir-100. Figure S12. Knockdown of mir-100 targets mimic the effects of mir-100 overexpression. Figure S13. Verification of SMARCA5 and SMARCD1 level by Western blot. Figure S14. SMARCA5 and SMARCD1 are direct and functional targets of mir-100 in SUM149 cells. Figure S15. Kaplan-Meier survival curves based on the expression of SMARCA5 and SMARCD1.
Supplementary Figure 8 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 1641KB, Supplementary Figure 8. Effects of agonistic anti-CD40 antibody on intratumoral infiltrating of immune cells.
Supplementary Figure 6 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 596KB, Supplementary Figure 6. TIB210 and GK1.5 mAbs efficiently deplete splenic and intratumoral CD8 and CD4 T cells.
Supplementary Figure 4 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 161KB, Supplementary Figure 4. PLX4720 treatment augments PD-1 expression on tumor infiltrating CD4 T cells.
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Figure 5. Apc TALENs cannot induce Apc mutated tumors, with or without DEN.
Supplementary Tables S1-S4 from Suppression of Deacetylase SIRT1 Mediates Tumor-Suppressive NOTCH Response and Offers a Novel Treatment Option in Metastatic Ewing Sarcoma
Authors: Ban Jozef , Aryee Dave N.T. , Fourtouna Argyro , van der Ent Wietske , Kauer Max , Niedan Stephan , Machado Isidro , Rodriguez-Galindo Carlos , Tirado Oscar M. , Schwentner Raphaela , Picci Piero , Flanagan Adrienne M. , Berg Verena , Strauss Sandra J. , Scotlandi Katia , Lawlor Elizabeth R. , Snaar-Jagalska Ewa , Llombart-Bosch Antonio , Kovar Heinrich
Published: April 2023

Supplementary Tables S1-S4. Identification of HEY1 regulated genes downstream of EWS-FLI1 silencing in Ewing sarcoma (S1); Combined immunohistochemical staining results for samples from patients with metastases at diagnosis on TMA1 and 2 according to site of metastasis (S2); Clinical characteristics and SIRT1 staining results of primary tumors from 43 ES patients treated at St. Jude Children´s Hospital between 1979 and 1987 using vincristine, doxorubicin, and cyclophosphamide-based regimens, with subsequent addition of ifosfamide and etoposide (S3); Materials used in the study (S4).
Supplementary Figure Legends from Suppression of Deacetylase SIRT1 Mediates Tumor-Suppressive NOTCH Response and Offers a Novel Treatment Option in Metastatic Ewing Sarcoma
Authors: Ban Jozef , Aryee Dave N.T. , Fourtouna Argyro , van der Ent Wietske , Kauer Max , Niedan Stephan , Machado Isidro , Rodriguez-Galindo Carlos , Tirado Oscar M. , Schwentner Raphaela , Picci Piero , Flanagan Adrienne M. , Berg Verena , Strauss Sandra J. , Scotlandi Katia , Lawlor Elizabeth R. , Snaar-Jagalska Ewa , Llombart-Bosch Antonio , Kovar Heinrich
Published: April 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S5.
Data Supplement from High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma
Authors: Barnhill Lisa M. , Williams Richard T. , Cohen Olga , Kim Youngjin , Batova Ayse , Mielke Jenna A. , Messer Karen , Pu Minya , Bao Lei , Yu Alice L. , Diccianni Mitchell B.
Published: April 2023

CAI2, p16 and ARF expression in normal tissue compared to levels in fibroblasts (Supp Figure S1); Growth comparison of low vs. high passage NMB7 cells (Supp Figure S2); Growth comparison of low vs. high passage NMB7 cells in the absence of serum or presence of RA (Supp Figure S3).
Supplementary Figure S3 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S3. siRNA targeting of RIP140.
Supplemental Figure Legends from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplemental Figure Legends
Supplemental Figure 3 from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplemental Figure 3: Relationship between endocytic activity and genetic alteration associated with cancer cell oncogenic transformation
Suppl Figure 2 from PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration-Resistant Prostate Cancer, Is a Mediator of Resistance to Androgen Deprivation Therapy
Authors: Hsieh Chen-Lin , Botta Ginevra , Gao Shuai , Li Tiantian , Van Allen Eliezer M. , Treacy Daniel J. , Cai Changmeng , He Housheng Hansen , Sweeney Christopher J. , Brown Myles , Balk Steven P. , Nelson Peter S. , Garraway Levi A. , Kantoff Philip W.
Published: April 2023

Suppl Figure 2. AR binds to PLZF locus and regulates its gene expression
Figure S2 from PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus–Induced Liver Carcinogenesis
Authors: Zhang Hao , Diab Ahmed , Fan Huitao , Mani Saravana Kumar Kailasam , Hullinger Ronald , Merle Philippe , Andrisani Ourania
Published: April 2023

Figure S2: Determination of half/life of SUZ12 and ZNF198 by cyclohexamide treatment
Supplementary Table S4 from Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations
Authors: Sawai Yugo , Kodama Yuzo , Shimizu Takahiro , Ota Yuji , Maruno Takahisa , Eso Yuji , Kurita Akira , Shiokawa Masahiro , Tsuji Yoshihisa , Uza Norimitsu , Matsumoto Yuko , Masui Toshihiko , Uemoto Shinji , Marusawa Hiroyuki , Chiba Tsutomu
Published: April 2023

Supplementary Table S4. List of mutations in pancreatic tissue of AID Tg mouse by whole exome sequencing.
Supplementary Table 1 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Table 1: Primers for Semi-quantitative RT-PCR
Supplementary Figure Legend from Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis
Authors: Ko Chun-Jung , Huang Cheng-Chung , Lin Hsin-Ying , Juan Chun-Pai , Lan Shao-Wei , Shyu Hsin-Yi , Wu Shang-Ru , Hsiao Pei-Wen , Huang Hsiang-Po , Shun Chia-Tung , Lee Ming-Shyue
Published: April 2023

Supplementary Figure Legend. Legend for Supplementary Figures S1-S5.
Supplementary Figures S1-S5 from CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus
Authors: Koh Siang-Boon , Courtin Aurélie , Boyce Richard J. , Boyle Robert G. , Richards Frances M. , Jodrell Duncan I.
Published: April 2023

Supplementary Figures S1-S5. Effective synergy at sub-GI50 concentrations (S1); Mitotic entry at synergistic concentrations (S2); Cell fate upon gemcitabine and CHK1 inhibition (S3); Replication stress upon gemcitabine and CHK1 inhibition (S4); Mitotic aberration upon gemcitabine and CHK1 inhibition (S5).
Supplementary Table S2 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: April 2023

Supplementary Table S2. Gene list.
Supplementary Figure 1 from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Authors: Lau Jasmine , Ilkhanizadeh Shirin , Wang Susan , Miroshnikova Yekaterina A. , Salvatierra Nicolas A. , Wong Robyn A. , Schmidt Christin , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: April 2023

Figure S1: Expression of mesenchymal genes, Pdpn and Chi3l1, in proneural and mesenchymal murine glioma models.