bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluación de bacterias rizosfericas asociadas a Pennisetum clandestinum como promotoras del crecimiento vegetal en condiciones de invernadero
Authors: Sánchez Diana , Gómez Ruth , Camelo Mauricio , Estrada Germán Andrés , Bonilla Ruth
Published: May 2023

El pasto Kikuyo (Pennisetum clandestinum) constituye la base de la alimentación de los sistemas ganaderos del Trópico Alto Colombiano. Esta gramínea posee un buen valor nutricional representada en su alta digestibilidad (representa una alternativa para la alimentación del ganado en los sistemas productivos colombianos). Uno de los principales problemas que presenta el cultivo de esta gramínea, es el alto costo de producción por el empleo de fertilizantes de síntesis química, tanto nitrogenados como fosfatados, lo cual deriva en impactos ecológicos y sociales negativos. Por esta razón, el uso de bacterias con capacidad biofertilizante representa una alternativa viable para sustituir parcialmente la fertilización química. El objetivo del presente estudio fue determinar algunas capacidades de promoción de crecimiento vegetal, tales como la solubilización de fósforo y la producción de sustancias tipo indol, de diferentes géneros bacterianos asociados a las plantas de Pennisetumclandestinum.
Effect of abiotic factors on viability and characterization of Metarhizium rileyi Nm017
Authors: Sanabria Johana , Quiroga Ginna , Mejía Cindy , Grijalba Erika , Goméz Martha
Published: May 2023

The species Chloridea virescens and Helicoverpa zea (Lepidoptera: Noctuidae) are declared agricultural pests with a high economic impact worldwide (Angulo et al. 2008). They are widely distributed on the American continent, and agrochemical are the most common method to control, which can cause environmental, social, economic and public impacts. A strain of Metarhizium rileyi Nm017 [AGROSAVIA - Orinoquia area (Col.)], demonstrated an e cacy of 75.8% on C. virescens, and 92.5% on H. zea on laboratory conditions. Mass production and virulence of Metarhizium sp. are susceptible to stress conditions such as temperature, UVB radiation and pH, a ecting conidial vigor, germination, and sporulation (Rangel et al. 2008, Oliveira et al. 2016). Likewise, the culture medium can a ect the infection processes measured through hydrophobicity and enzymatic activities (Ortiz 2013). The identi cation of these parameters allows selecting the most favorable conditions for its production and the challenges that must be assumed in downstream processes.
Evaluación del contenido de metabolitos secundarios en recursos forrajeros del trópico colombiano mediante espectroscopia de infrarrojo
Authors: Duran E. , Mayorga O. , Calvo A. , Parra D. , Mestra L.
Published: May 2023

La producción ganadera en Colombia se basa en el pastoreo y los recursos forrajeros provienen principalmente de gramíneas (GF), leguminosas (LF) y/o arbóreas (AF), los cuales pueden contener metabolitos secundarios como taninos, saponinas, compuestos fenólicos y alcaloides, y que dependiendo de su concentración pueden causar efectos negativos a nivel fisiológico y/o nutricional o modular en forma positiva el ecosistema ruminal de los animales [1]. Definir una metodología única para cada uno de los compuestos y los tipos de forrajes en el marco de la biodiversidad colombiana genera un reto para explorar la potencialidad de los recursos forrajeros de los sistemas de producción colombiana. La espectroscopia de infrarrojo cercano (NIRS) está siendo usada para determinar la composición de macro-componentes de los forrajes [2] y podría ser utilizada para predecir la concentración de metabolitos secundarios.
Características reproductivas de machos ovinos bajo las condiciones ambientales del Caribe húmedo colombiano
Authors: Carrascal Triana E.L , Herrera Pérez N , Salcedo Carrascal E.P. , García Jiménez J.A
Published: May 2023

La selección de machos es importante para la e ciencia reproductiva, una vez que los machos con buena fertilidad pueden servir un gran número de ovejas en corto tiempo, diseminando el material genético deseado. El objetivo del presente estudio fue caracterizar reproductivamente los machos ovinos de la región húmeda del Caribe colombiano.
Uso de aumentorios para el manejo de mosca de la fruta con parasitoides en mango
Authors: Varón Devia Edgar Herney , Flórez Cárdenas Claudia Milena , Arcila Cardona Angela María
Published: May 2023

El presente trabajo propone la conservación y aumento de las poblaciones del parasitoide nativo D. areolatus, a través del uso de dispositivos tipo tienda llamados aumentorios, en los que se disponen los frutos, y permiten la liberación de los parasitoides presentes, sin permitir la salida de las moscas de la fruta.
Correlación entre el índice moscas/trampa/día y la incidencia en frutos de Anastrepha obliqua Macquart (Diptera:Tephritidae) en cultivos comerciales de mango de azúcar en el Magdalena
Authors: Brochero Bustamante Carlos Esteban , Guzmán Sánchez Luisa F. , Arcila Cardona Angela M. , Varón D. Edgar H.
Published: May 2023

La mosca de la fruta Anastrepha obliqua es la plaga más importante del cultivo de mango (Mangifera indica L.) en Colombia, y una seria limitante para la exportación de fruta fresca (Osorio-Fajardo y Canal, 2011; Castañeda et al. 2015). El índice moscas/trampa/día (MTD) se calcula teniendo en cuenta la captura de adultos de moscas de la fruta por medio de trampas, y se utiliza para el monitoreo y la toma de decisiones sobre prácticas de manejo de este insecto. El objetivo de este trabajo fue evaluar la correlación entre el índice MTD y la incidencia de larvas de A. obliqua en frutos de mango variedad azúcar, en ncas productoras del norte del departamento del Magdalena.
The Kinetics of Anti–SARS-CoV-2 Antibodies in Pediatric Patients and the Characterization of Post–COVID-19 Condition at 6 Months After Infection: Protocol for a Longitudinal Observational Study
Authors: Arguni Eggi , Chamida Fatia Murni , Indrawanti Ratni , Rusmawatiningtyas Desy , Dewi Yunika Puspa , Laksanawati Ida Safitri
Published: May 2023

Background

Data regarding the kinetics of anti–SARS-CoV-2 antibodies and information about post–COVID-19 condition (colloquially known as “long COVID”) in children are scarce, especially in low-income countries. Even though cases of COVID-19 in children are less prevalent than adults, post–COVID-19 condition cases in children are high and have a burden that may impact their growth and development. There are other features of antibody kinetics in connection with SARS-CoV-2 infection that are yet unknown as of this writing, especially in children following infection. Furthermore, the long-term results, risk factors, and underlying pathophysiology are still uncertain. To better understand post–COVID-19 condition in children, it is necessary to further investigate the impact of clinically significant factors such multisystem inflammatory syndrome and disease severity among hospitalized survivors through their SARS-CoV-2 antibody response.

Objective

We aim to analyze anti–receptor-binding domain SARS-CoV-2 immunoglobulin G antibodies over time and characterize the signs and symptoms of post–COVID-19 condition in pediatric patients at the time of diagnosis and at 2 weeks and 1, 3, and 6 months following infection.

Methods

This is a longitudinal observational study in Indonesia. Pediatric patients diagnosed with COVID-19 by positive molecular assay using nasopharyngeal swab will be tested for anti–SARS-CoV-2 antibodies using the Roche Elecsys Anti-SARS-CoV-2 S assay at the time of diagnosis and at 2 weeks and 1, 3, and 6 months following infection. Antibody titer data will be reported as means and SDs. The respondents’ signs and symptoms will be observed up to 6 months after the onset of infection, including the vaccination event, reinfection, rehospitalization, and mortality. The clinical features will be reported as frequencies and percentages.

Results

Participant enrollment began in February 2022. As of September 30, 2022, a total of 58 patients were enrolled. After data collection, results are expected to be analyzed in August 2023.

Conclusions

This study will allow us to know the kinetics of anti–receptor-binding domain SARS-CoV-2 immunoglobulin G antibodies and data regarding post–COVID-19 condition up to 6 months following infection in the Indonesian pediatric population. Furthermore, this study has the potential to serve as a foundation for government decisions about vaccination programs and prevention measures.

International Registered Report Identifier (IRRID)

DERR1-10.2196/43344
Modelación de la sobrepoblación relativa en localidades de Chiapas: análisis espacial bayesiano
Authors: Calderón Villarreal Cuauhtémoc , Núñez Medina Gerardo , Hernandez Bielma Leticia
Published: May 2023

El objetivo de este trabajo es identificar patrones de distribución espacial de la sobrepoblación relativa, medida por la Población Económicamente Activa y la migración, en localidades del estado de Chiapas en 2020. Se aplican técnicas de análisis exploratorio de datos espaciales y modelos gaussianos latentes y se utiliza la tasa de inmigración como covariable en dos modelos empíricos distintos. El ajuste de dichos modelos se realiza empleando el paquete R-INLA. Los resultados parecen indicar la existencia de un conjunto de conglomerados y agrupaciones espaciales de PEA alrededor de la capital del estado de Chiapas.
Multidisciplinary Integration in Undergraduate Environmental Protection Design Innovation
Authors: Xijing Liu
Published: May 2023

This paper examines the necessity and implementation of multidisciplinary integration in undergraduate environmental protection design innovation, using the 4th Urban Water Environment and Water Ecology Creative Competition as a case study. Firstly, it explores the significance of the innovation competition itself as a foundation for analyzing the impact of multidisciplinary integration on the development of participating students, faculty teams, and the advancement of disciplines. Secondly, it provides a detailed discussion on the outstanding achievements attained through the integration of three disciplines, namely environmental engineering, computer science, and art and design, within the context of the Water Environment and Water Ecology Creative Competition. Lastly, the paper concludes by summarizing the importance and value of multidisciplinary integration in undergraduate environmental protection design innovation. By presenting the insights and analysis outlined in this paper, readers can gain a comprehensive understanding of the role played by multidisciplinary integration in environmental protection design innovation, thereby offering valuable ideas and perspectives for teaching and research in related fields.
The Relationship between Business Intelligence and Organizational Agility with Emphasis on the Mediating Role of IT Infrastructure Flexibility (Case Study: Active Companies in Rasht Industrial City)
Authors: Taleghani Mohammad , Gilaninia Shahram
Published: May 2023

The purpose of this research was to investigate the relationship between business intelligence and organizational agility, emphasizing the mediating role of IT infrastructure flexibility in companies operating in Rasht Industrial City. The current research is a cross-sectional and correlational research, and its statistical population consists of all managers of active companies in Rasht Industrial City, and 255 samples that were selected based on Morgan’s table and by random sampling were used for analysis. Descriptive analyses were performed using SPSS 22 statistical software and final analysis was performed using Smart PLS 2 statistical software. The results of the research showed that business intelligence has a significant relationship with organization agility and IT infrastructure flexibility, and IT infrastructure flexibility has a significant relationship with organization agility. Also, the analysis results confirmed the mediating role of IT infrastructure flexibility in the relationship between business intelligence and organization agility, but the moderating role of IT infrastructure flexibility in the relationship between business intelligence and organization agility was not confirmed. Based on the results of the research, in addition to analysing key information and optimizing strategic decisions, company managers can use business intelligence as a tool to master new technologies for the development and prosperity of IT infrastructures.
Mitos, paradojas e interrogantes abiertas sobre la presencia negra en el Reyno de Chile
Authors: Ardito Aldana Lorena
Published: May 2023

Ante una coyuntura histórica constituyente, el presente artículo indaga mitos, paradojas e interrogantes abiertas sobre la presencia africana y afrodescendiente en Chile. Desde una aproximación interdisciplinaria, se parte desde la historiografía para abrir la mirada hacia el folclor, la musicología, la literatura y la investigación antropológica reciente, abriendo un diálogo con voces afrochilenas contemporáneas. Se concluye que la invisibilización histórica de la presencia “negra”, ha tenido un carácter eminentemente paradójico; se niega su existencia, a la vez que se persiguen expresiones de su especificidad, afirmándola. O bien, se legaliza su existencia, pero se impide su efectiva participación en la (re)construcción de lo nacional.
MANAGEMENT OF LABOR COLLECTIVES, WORKING CREW METHOD (on the example of the company “Weatherford”)
Authors: Tarasov M. N. , Galiakhmetov R. A.
Published: May 2023

The labor market in the Russian Federation shows a surge of vacancies in the oil and gas industry; there is a lot of competition among job applicants. The peculiarities of work at oil and gas enterprises are revealed, this specificity of the work lies in the fact that the development of fields is located in remote regions of the country, where there is almost no population, therefore, enterprises are forced to send employees to their workplaces using a rotational work method. The rotational work method carries some of the features that the employer must decide. Special requirements must be applied to shift personnel, in addition to their qualifications and work experience, their psychological characteristics must be taken into account, because a shift involves long-term work in harsh natural conditions, a limited circle of friends. Working on a rotational basis requires workers to be particularly precise in their work and is extremely dangerous. It is important for enterprise managers to take all possible measures to create a comfortable environment for employees and to prevent any failures and harmonize the psychological state of employees. The oil and gas industry needs highly qualified personnel and extensive experience. But the analysis of the labor market suggests that there are problems with labor resources, there are problems with personnel in the oil and gas industry. Let us consider the problems faced by enterprises operating in the raw materials industry on the example of the international company “Weatherford International Ltd”.
PROBLEMS OF ACCOUNTING CENTRALIZATION STATE INSTITUTIONS OF THE UDMURT REPUBLIC
Authors: Dekterev D. S. , Zemtsova N. V.
Published: May 2023

Improving the efficiency of budget spending is one of the key areas for the country's budget system as a whole and its subjects. Currently, the issues of optimizing the activities of state and municipal institutions, reducing the cost of financial resources at the sub-federal level are solved using the mechanism of centralized accounting. In the Udmurt Republic, in 2019, the process of optimizing public sector institutions was started, due to the centralization of accounting, work is currently underway to build a unified information system for accounting and personnel accounting, and introduce a centralized reporting system. The process of centralization is not finished at the moment, the article studies the current situation on the coverage of centralization of state institutions of the Udmurt Republic. The main problems arising during the implementation of the project on the centralization of accounting in the region are identified. The ways of solving the identified problems are proposed and justified for the further development of the process of centralization of accounting, reducing the costs of performing accounting functions, for the rapid collection and analysis of information necessary for the heads of state institutions, state authorities of the Udmurt Republic to make effective management decisions.
PROCESS MINING: PRINCIPLES, CHARACTERISTICS AND IMPLEMENTATION POTENTIAL
Authors: Zakurdaeva Zh. E. , Bikeeva M. V.
Published: May 2023

Digital transformation is forcing companies to rethink their processes to meet current customer needs. Business Process Management (BPM) can provide a means to structure and address this change. However, most BPM approaches face limitations on the number of processes they can optimize at the same time, due to complexity and resource constraints. The article is devoted to data mining as a tool for modeling and improving the company's business processes. Process Mining is a collection of data-driven diagnostic and business process improvement methods that combine machine learning and BPM. Among the advantages of Process Mining is more efficient management decision making. The possibility of introducing Process Mining methods into the work of a telecommunications company for the automatic collection of information about business processes and building a map of business processes is analyzed. The use of Process Mining methods will allow a telecommunications company to optimize the work of its departments and increase customer satisfaction. In addition, the implementation of this system contributes to a better analysis of the results of the execution of business processes for providing access to the Internet. This will improve the regulations for these processes, control of their compliance and the procedure for making managerial decisions at a higher quality level.
PROFESSIONAL LANGUAGE COMPETENCE OF TECHNICAL UNIVERSITY STUDENT: CONCEPT, STRUCTURE, DEVELOPMENTAL SPECIFICS
Authors: Gareyev A. A.
Published: May 2023

The use of competence-based approach in higher technical education demands a certain degree of precision from teachers and researchers when building a structure of a competence. This paper explores foreign language training in a technical university. It discusses the specifics of a concept of competence in the context of a technical university taking into account its qualimetric nature, the ability to measure the results of its development. Also, the concept, structure and developmental specifics of a complex, professional language competence relevant for technical universities are presented. Based on the literature review and the use of method of group expert assessment, the structure of professional language competence for a technical university student is identified. It consists of three its most significant components: communicative, cognitive and domain-specific. With that, the domain-specific component implies two individual educational trajectories which correspond to the needs of future graduates. The presented structure lays the foundation of a pedagogical model and technology developed by the author and can be used for other pedagogical solutions and experiments.
Text Summarizer Using SpaCy in NLP
Authors: Lade Sangita
Published: May 2023

Abstract: Using machine learning and natural language processing techniques to summarize the huge volume of text data and give a short summary. To develop a system which identifies contexts of a document and give the best possible summarized text with the help of SpaCy in natural language processing.
Lasers in Defence
Authors: Bisht Devyani , Sharma Dr. Homdutt
Published: May 2023

Abstract: The development and usage of laser technology in fields such as defence, law enforcement, communication, and defence have had a major impact on the law enforcement sector. The idea of Light Amplification by Stimulated Emission of Radiation (LASER) was conceived in 1957, but it wasn't until 1960 that Theodore H. Maiman built the first practical application of the technology. In addition to its high coherence and intensity, laser illumination is also distinguished by its spatial coherence, enabling light pulses on the femtosecond timescale. It finds use in various disciplines, including holography, the space sciences, spectroscopy, medicine, microelectronics, power electronics, industrial engineering, and even directed energy weaponry. Laser target markers and beam riders are the most common methods for accurately controlling LGW towards ground objects. Recent advances in laser technology are intensively investigated for their potential use in target indicators and range finders. There has been an increase in the usage of lasers in recent years, with several new services in fields as diverse as commerce, industry, medicine, science, technology, and even the military. Applications like range finders, target designators, power beamers, LIDARs, and long-range, high-speed, secure communication systems have the potential to completely alter the face of combat. India's laser R&D centres are working on various laser systems and their supporting components and materials for use in directed energy applications. Laser crosslinks are a technology that can maintain data speeds in the tens of gigabits, and they give higher bit rates with decreased bit error rates owing to their small wavelengths.
Machine Learning Techniques for Coronary Artery Bypass Prediction
Authors: . Naveen
Published: May 2023

Abstract: Heart failure, a complicated clinical problem,presently affects a smaller number of persons globally. Earlyon, cardiac centres and hospitals rely significantly on ECG toassess and diagnose heart failure. The utilization of an electrocardiogram, also known as ECG, is widespread in themedical field. Detecting heart ailments at an early stageremains a crucial challenge in the healthcare industry. The focus of this paper is to introduce various machine learning technologies for the detailed analysis of heart ailment detection. First, a weighted version of Nave Bayes is employed to forecast cardiac problems. The alternate bone, according to This system is designed for the automatic and anatomical localization/discovery of ischemic heart complaints. The system utilizes two classifiers that are similar to support vector machine (SVM) and XGBoost with swish performance, respectively. The system analyzes the features of the frequency sphere, time sphere, and information proposition to accurately locate and detect ischemic heart complaints. The third bone is an automated detection system for heart failure based on a bettered SVM based on the duality optimisation approach that was previously studied. To support clinical decision-making, a Heart Complaint Prediction Model (HDPM) is utilized in a Clinical Decision Support System (CDSS). As a result, treating problems properly and avoiding significant consequences will be easy. In order to evaluate essential decision tree-type algorithms for honing the finesse of heart complaint opinion, this study employs XGBoost. Four types of machine knowledge (ML) models are examined in terms of perfection, delicacy, f1-measure, and recall as performancecriteria.
IOT based Home Automation System
Authors: Tomar Vaibhav
Published: May 2023

Abstract: This research paper presents an IoT-based home automation system that uses an ESP32 microcontroller to communicate using the ESP32 NOW protocol. The system allows users to remotely monitor and control home appliances through a mobile application. The paper discusses the hardware and software components of the system, including the ESP32 microcontroller, sensors and actuators, and mobile applications. It also describes the communication protocols used for data transfer and user interface design for mobile applications. The proposed system offers several advantages such as low power consumption, high data transfer rate and easy scalability. It also offers users an easy and friendly interface to manage home devices remotely. The results of the experimental evaluation of the system show its efficiency and reliability, indicating that it can be a promising solution for the implementation of smart home automation. Overall, this paper provides valuable insights into the development of IoT-based home automation systems using ESP32 and Flutter technologies that can be useful for researchers and practitioners interested in this field.
Contestation and Perseverance in a time of Competing Crises: An Intersectional Analysis of Young Women and Girls’ Climate Activism During COVID-19
Authors: Bendo Daniella , Goodwin-De Faria Christine , Ciufo Dustin
Published: May 2023

Risks associated with the COVID-19 pandemic disproportionately impact young people already occupying challenging circumstances, including young women and girls experiencing gender discrimination, exploitation and economic exclusion. Nevertheless, young women and girls are among the most active in shaping local/global responses. Through an intersectional approach that critically explores child and youth civil and political rights, this paper analyzes climate change activism led by young women and girls during COVID-19, as well as the intersectional complexities that impact the activism that they engage in and carry out. We argue that despite the negative impacts of the pandemic, young women and girls have opened new participatory spaces to positively shape our environment, while also navigating and defying gendered barriers, both in the present and for future generations.
La protection des droits des demandeurs d’asile mineurs dans le Règlement de Dublin III face aux exigences de la CEDH
Authors: Samson Juliette , Labrecque Gabrielle-Anne
Published: May 2023

Adopté en 2013, le règlement de Dublin III impose aux membres de l’Union Européenne (UE) la règle générale selon laquelle le pays responsable de traiter une demande d’asile est le pays par lequel le demandeur est entré dans l’UE. Ce règlement a fait face à une forte critique, notamment en ce qui concerne la protection qu’il offre aux demandeurs d’asile mineurs. Il appert que celui-ci ne permet pas aux pays d’entrée de leur offrir une protection adéquate. La forte concentration des demandes d’asile que crée le règlement de Dublin III nuit de façon exacerbée aux mineurs demandeurs d’asile en raison de leur vulnérabilité particulière. En effet, cette vulnérabilité requiert une mobilisation de ressources supérieure à celle qui est requise pour les adultes. Cela rend difficile, voir impossible, l’évaluation et le respect de l’intérêt supérieur des demandeurs d’asile mineurs. Le présent texte examine cette dynamique dans le cadre du droit à la liberté et du droit à la protection de la vie familiale, tels que protégés par la Convention européenne des droits de l’Homme (CEDH).
La Discrimination À L’égard Des Enfants Autochtones Au Québec : Regard Sur L’application Indifférenciée De La Loi Sur La Protection De La Jeunesse
Authors: Garcia Emmanuelle
Published: May 2023

Cet article porte sur la divergence et l’incompatibilité de certaines valeurs et principes sous-tendant la Loi sur la protection de la jeunesse au Québec lorsqu’appliquée aux enfants des Premières Nations, des Inuit et des Métis. Notamment, les représentations différentes de la famille et de l’intérêt de l’enfant, la pertinence de la continuité culturelle ainsi que la validité des théories d’attachement et du principe de permanence seront analysés à la lueur des écrits juridiques nationaux et internationaux s’appliquant à la situation de ces familles.

 

          Mots-clés : peuples autochtones, familles, éducation des enfants, parentalité, continuité culturelle, attachement, permanence, intérêt de l’enfant autochtone, relations avec l’État, service social aux autochtones – Québec

 

This article examines the difference and incompatibility of some of the values and principles underlying the Quebec Youth Protection Act when applied to First Nations, Inuit and Métis children. In particular, the different representations of the family and the child's interest, the relevance of cultural continuity as well as the validity of attachment theories and the principle of permanence will be analyzed in regards to the national and international legal writings that apply to the situation of these families.
Penerapan Media Flipbook untuk Meningkatkan Literasi Membaca Siswa SD
Authors: Binti Mirnawati Lilik , Agatha Valent Fabriya Regy
Published: May 2023

Indonesia is one of the countries in Asia with low reading literacy skills. Therefore, the mastery of reading literacy is vital for students and the Indonesian people. This study aims to describe the process of implementing flipbook media that can improve the reading literacy of 2nd graders of elementary school and measure the improvement of their reading literacy after the application of flipbook media. The method used is Classroom Action Research. The data collection uses observation techniques and documentation, and the literacy tests uses test sheets and documentation. The subjects of this research are 17 elementary school students in the 2nd grade of Muhammadiyah Elementary School 8 Surabaya. Based on the study results, the data show that flipbook media was applied online at the habituation stage and was carried out for 15 minutes before reading. The application of online-based flipbook media can improve students’ reading literacy and learning activities of the 2nd-grade students of Muhammadiyah Elementary School 8 Surabaya. The increase in reading literacy results can be seen in the literacy test results carried out in 2 learning cycles. Before applying flipbook, the result of classical literacy completeness was 29.41%. In the first cycle, the acquisition of classical reading literacy mastery was 47.06%, while in the second cycle, the classical completeness was 82.35%. So, it can be concluded that the use of flipbook media can improve the reading literacy of the 2nd-grade students of Muhammadiyah Elementary School 8 Surabaya
Pengembangan Lembar Kerja Siswa Materi Gerak Dasar Berisi Konten Berbasis Permainan Tradisional Kalimantan Utara
Authors: Mas’an Al Wahid Sucahyo
Published: May 2023

form of books. The purpose of this study was to determine the quality of materials and media in locomotor, non-locomotor and manipulative learning devices containing traditional game content. The research site was carried out in class II were 20 students. The research uses a research and development approach through the Dick & Carey model with 7 stages. The results of the study on indicators of introducing the traditional game of switching stars, taxes and pickles on the content feasibility achievement with an average overall score of 3, then the demonstration indicator through pictures on the presentation achievement obtained an average score of 2.25, as well as indicators of the use and attractiveness of letters on the achievement language and readability score 2. The assessment also consists of device assessment, and LKS assessment (material expert and media expert). The assessment obtained in the assessment of learning devices obtained a percentage of 88.89% which means that it meets the valid criteria. Meanwhile, the LKS assessment is based on the validation results of material and media experts, both of which get a percentage value of 90%, which means it is valid
Quantum Lock: A Provable Quantum Communication Advantage
Authors: Chakraborty Kaushik , Doosti Mina , Ma Yao , Wadhwa Chirag , Arapinis Myrto , Kashefi Elham
Published: May 2023

Physical unclonable functions(PUFs) provide a unique fingerprint to a physical entity by exploiting the inherent physical randomness. Gao et al. discussed the vulnerability of most current-day PUFs to sophisticated machine learning-based attacks. We address this problem by integrating classical PUFs and existing quantum communication technology. Specifically, this paper proposes a generic design of provably secure PUFs, called hybrid locked PUFs(HLPUFs), providing a practical solution for securing classical PUFs. An HLPUF uses a classical PUF(CPUF), and encodes the output into non-orthogonal quantum states to hide the outcomes of the underlying CPUF from any adversary. Here we introduce a quantum lock to protect the HLPUFs from any general adversaries. The indistinguishability property of the non-orthogonal quantum states, together with the quantum lockdown technique prevents the adversary from accessing the outcome of the CPUFs. Moreover, we show that by exploiting non-classical properties of quantum states, the HLPUF allows the server to reuse the challenge-response pairs for further client authentication. This result provides an efficient solution for running PUF-based client authentication for an extended period while maintaining a small-sized challenge-response pairs database on the server side. Later, we support our theoretical contributions by instantiating the HLPUFs design using accessible real-world CPUFs. We use the optimal classical machine-learning attacks to forge both the CPUFs and HLPUFs, and we certify the security gap in our numerical simulation for construction which is ready for implementation.
Pengaruh Minat Siswa pada Pembelajaran Biologi Terhadap Hasil Belajar Siswa SMA N 1 Beringin
Authors: Wahyuda Agus , Ananda Putri Ananda Putri , Humayroh Siti , Reni Rahayu Reni Rahayu , Azzahra Putri Ramadana Azzahra Putri Ramadana
Published: May 2023

The aim of this study is to investigate the effect of students' interest in biology on academic performance. This study was conducted at SMA N 1 Beringjin in 2022. This type of survey is a sample survey of 90 students in the 11th MIPA class. The research tool was a Google Forms questionnaire with 30 questions, administered to students. The indicators of the survey are the pleasure, interest, interest and participation of students in biology. The data analysis was performed by calculating the survey score of each student, applying it to the presentation and interpreting it into categories of good, good, bad and poor. As a result, the students 'pleasure was 77.9%, the students' interest was 77.1%, the students 'interest was 76.1% and the students' participation was 75.9%. Following this study, it was found that students 'interest in learning had a positive effect on students' school results, and the average level of interest in biological research in Beringin Class XI SMAN 1 in 2022 was 76.75, a very good category, seemed to correspond with expected.
Key words: Interest, Biology Learning, Learning Outcome
 
ABSTRAK
Tujuan dari penelitian ini adalah untuk mengetahui pengaruh minat siswa pada biologi terhadap prestasi akademik. Penelitian ini dilakukan di SMA N 1 Beringjin pada tahun 2022. Jenis survei ini adalah sampel survei terhadap 90 siswa kelas XI MIPA. Alat penelitian adalah kuesioner Google Forms dengan 30 pertanyaan, diberikan kepada siswa. Indikator survei adalah kesenangan, minat, minat dan partisipasi siswa dalam biologi. Analisis data dilakukan dengan menghitung skor survei masing-masing siswa, menerapkannya pada presentasi dan menginterpretasikannya ke dalam kategori baik, baik, buruk dan buruk. Hasilnya, kesenangan siswa sebesar 77,9%, minat siswa sebesar 77,1%, minat siswa sebesar 76,1% dan partisipasi siswa sebesar 75,9%. Berdasarkan penelitian ini diketahui bahwa minat belajar siswa berpengaruh positif terhadap hasil belajar siswa, dan rata-rata tingkat minat penelitian biologi pada siswa kelas XI SMAN 1 Beringin tahun 2022 adalah 76,75 dengan kategori sangat baik, tampaknya sesuai dengan yang diharapkan.
Kata kunci: Minat, Pembelajaran Biologi, Hasil Belajar
Good corporate governance and moderating the influence of intellectual capital on the financial performance: The study of the Islamic banking industry
Authors: Faozan Akhmad , Syah Toufan Aldian , Kusuma Hadri , Adawiyah Wiwiek Rabiatul
Published: May 2023

The importance of intellectual capital (IC) in the financial sector has become increasingly evident in the Fourth Industrial Revolution (4IR). Tayles et al. (2007) have shown that companies must acknowledge, incentivize, and oversee their IC to achieve sustainable performance excellence. This study investigates the impact of IC on the financial performance of Sharia banking in Indonesia and assesses the role of good corporate governance (GCG) in enhancing the connection between IC and financial performance. Data were collected from 14 Islamic banks throughout Indonesia based on quarterly data over five years, from 2015 to 2019, and involved 266 observations. This study employed the generalized method of moments (GMM) estimator to examine empirical data and observed that intellectual capital has a beneficial impact when GCG is a moderator. The paper adds to the current literature by introducing a new analytical framework that explores the role of GCG in moderating the relationship between intellectual capital and financial performance.
Durable and Dramatic Response to Checkpoint Inhibition Combined with IDO1 Inhibitor Celecoxib in a Patient with p16+ Metastatic Sinonasal Undifferentiated Carcinoma
Authors: Trinh Jonathan , Easwar Arti , Galamaga Robert , Tan Alan
Published: May 2023

Background: Sinonasal undifferentiated carcinoma (SNUC) is an
exceedingly rare head and neck malignancy. No consensus exists on
treatment for metastatic disease. Case: A 56-year-old female was
diagnosed with SNUC after endorsing sinus congestion, diplopia, and
right orbital pain. Initially treated with surgery and radiation, she
later developed significant metastatic disease. She demonstrated
progression of her hepatic metastases under pembrolizumab therapy.
However, the addition of ipilimumab and an IDO1 inhibitor resulted in
significant improvement in her lesions as well as an ongoing durable
response. Her regimen was complicated by immune-related adverse events
successfully treated with steroids. Conclusion: Dual checkpoint
inhibition deserves consideration when treating metastatic SNUC,
especially after single agent therapy has failed. The positive effect of
this treatment may be augmented by IDO1 inhibition.
Rebamipide Protects Against Intervertebral Disc Degeneration Through Suppression of NF-κB Signaling Pathway
Authors: Liu Jinbo , Zhang Yuanqiang , Xiang Chongxin , Si Meng , Ma Hecheng
Published: May 2023

Intervertebral disc (IVD) degeneration is a common chronic degenerative
and disabling spinal disease in which the inflammatory response plays a
crucial role. Rebamipide (REB) prevents gastric mucosal damage by
suppressing inflammatory cytokines via the NF-κB signaling pathway. The
aim of this study was to investigate how REB affects the pathological
process of IVD degeneration. In our study, nucleus pulposus tissue and
cells were obtained from patients and mice, and western blotting,
real-time PCR, immunohistochemistry, immunofluorescence, histological
staining, and flow cytometry were used to identify the mechanism of REB
in TNF-α-induced IVD degeneration, demonstrating that TNF-α induced
lumbar disc degeneration and REB prevented lumbar disc degeneration
induced by the TNF-α pathway. REB inhibited TNF-α-mediated degradation
of the extracellular matrix and protected the inflammatory responses of
TNF-α-induced disc degeneration. Furthermore, a mechanistic study
verified that REB could suppress TNF-α-mediated disc degeneration
through the NF-κB signaling pathway. The role of REB in disc
degeneration in vivo was validated using a needle puncture model in
rats. Overall, REB inhibited lumbar disc degeneration by suppressing
inflammatory responses via the NF-κB signaling pathway. REB provides a
potential therapeutic treatment for back pain due to IVDD.
Rational design and experimental evaluation of peptide ligands for the purification of adeno-associated viruses via affinity chromatography
Authors: Shastry Shriarjun , CHU WENNING , Barbieri Eduardo , Greback-Clarke Paul , Smith William , Cummings Christopher , Minzoni Ariann , Pancorbo Jenifer , Gilleskie Gary , Ritola Kimberly , Daniele Michael , Menegatti Stefano
Published: May 2023

Adeno-associated viruses (AAVs) have acquired a central role in modern
medicine as delivery agents for gene therapies targeting rare diseases.
While new AAVs with improved tissue targeting, potency, and safety are
being introduced, their biomanufacturing technology is lagging. The AAV
purification pipeline, in particular, hinges on protein ligands for the
affinity-based capture step: while featuring excellent AAV binding
capacity and selectivity, these ligands require strong acid (pH
<3) elution conditions, which can compromise the product’s
activity and stability; additionally, their high cost and limited
lifetime has a significant impact on the price tag of AAV-based
therapies. Seeking to introduce a more robust and affordable – yet
equally effective – affinity technology, this study introduces a cohort
of peptide ligands that (i) mimic the biorecognition activity of the AAV
receptor (AAVR) and anti-AAV antibody A20, while (ii) enabling product
elution under near-physiological conditions (pH 6.0) and (iii) granting
extended reusability by withstanding multiple regenerations. A20-mimetic
CYIHFSGYTNYNPSLKSC and AAVR-mimetic CVIDGSQSTDDDKIC demonstrated
excellent capture of serotypes belonging to distinct clones/clades –
AAV1, AAV2, AAV5, AAV6, AAV8, and AAV9 – corroborating the in silico
models documenting their ability to target regions of the viral capsid
that are conserved across all serotypes. CVIDGSQSTDDDKIC-Toyopearl resin
features binding capacity (~1014 vp per mL) and product
yields (~60-80%) on par with commercial adsorbents, and
purified AAV2 from HEK293 and Sf9 cell lysates affording high recovery
(up to 78%) and reduction of host cell proteins (up to 700-fold), and
high transduction activity (up to 65%) of the purified vectors.
Transcriptomics and metabolomics analyses reveal the differential molecular mechanisms of cold tolerance between Cavendish and Dajiao banana cells
Authors: Yang Qiaosong , Wu Shuo-Fan , Hu Chun-Hua , Zhang Sheng , Deng Gui-Ming , Sheng Ou , Dou Tong-Xin , Bi Fang-Cheng , He Wei-Di , Dong Tao , Li Chunyu , Liu Si-Wen , Gao Hui-Jun , Yi Ganjun , Yao Zhen
Published: May 2023

Low temperature is a major environmental factor that limits the growth,
yield, and geographical distribution of bananas. Given the complex
nature of cold tolerance traits in bananas, the molecular mechanisms and
associated gene networks responsible for cold tolerance are poorly
understood. The aim of this study is to identify cold stress response
genes, metabolites, and metabolic pathways through integrated
transcriptomics and metabolomics analyses, with the goal of
comprehensively understanding the mechanism underlying the differential
cold tolerance between cold-sensitive Cavendish and cold-tolerant Dajiao
bananas. Our findings show that cold-tolerant Dajiao accumulates more
lipids than cold-sensitive Cavendish under cold stress. Moreover, we
identified 4626 and 5516 differentially expressed genes under cold
stress in Cavendish and Dajiao, respectively. By integrating the
transcriptomic and metabolomic datasets, we discovered that the lipid
metabolism pathway and the ABA-independent MAPK cascade-ICE1 signal
transduction pathway play crucial roles in cold tolerance of Dajiao. Our
study provides new insight into the molecular basis of cold response and
the mechanism of cold tolerance in bananas, with potential applications
for genetic improvement of cold tolerance in bananas.
Elucidating the dynamic remodelling of Escherichia Coli interactome in different growth conditions using multiplex co-fractionation MS (mCF-MS)
Authors: Low Teck Yew
Published: May 2023

Most proteins function by forming complexes within a dynamic
interconnected network that underlies various biological mechanisms. To
systematically investigate such interactomes, high-throughput techniques
including CF-MS have been developed to capture, identify, and quantify
protein-protein interactions (PPIs) in large-scale. Compared to other
techniques, CF-MS allows the global identification and quantification of
native protein complexes in one setting, without genetic manipulation
and overexpression. Furthermore, quantitative CF-MS can potentially
elucidate the distribution of a protein in multiple co-elution features,
informing the stoichiometries and dynamics of a target protein complex.
In this issue, Youssef et al. (Proteomics 2023, XX, XXXX-XXXX) combined
multiplex CF-MS and an in-house algorithm to study the dynamics of the
PPI network for Escherichia coli grown under ten different conditions.
While the results demonstrated that while most proteins remained stable,
the authors were able to detect disrupted interactions that were growth
condition-specific. Further bioinformatics analyses also revealed
biophysical properties and structural patterns that govern such a
response.
Image perception of forest tourism destinations based on web text analysis------ A case study of Zhangjiajie National Forest Park
Authors: CHEN hao , Liu zhiyi , Wang min , Zheng shanting
Published: May 2023

This paper analyzes tourists’ perceptions of Zhangjiajie National Forest
Park from two aspects: cognitive image and emotional image. After
collecting and combining 5,109 valid travelogues from the online travel
platform of Ma Hive, ROST CM6 software was used to analyze
high-frequency words, the semantic network and the emotional content;
this results show that tourist perceptions of Zhangjiajie National
Forest Park mainly fall into seven categories, including resources,
facilities, excursions, management services, personnel, space, and
evaluation. The natural resources and ecological environment are the
core elements of the park’s image, and the facilities and management
services during tours are also important for tourists. Tourists
expressed positive emotions about the natural resources of the scenic
area and the unique tourism facilities such as the glass platform and
the sky stairs, while negative emotions were mainly expressed about the
infrastructure and service facilities. Based on these findings, this
paper proposes strict protections for natural resources, a focus on
developing cultural knowledge, improved tourism infrastructure, enhanced
management services and other suggestions for the development of forest
tourism destinations.
Cardiovascular and Renal Benefits of Novel Diabetes Drugs by Baseline Cardiovascular Risk: A Systematic Review, Meta-Analysis, and Meta-Regression
Authors: Rodriguez-Valadez José M. , Tahsin Malak , E. Fleischmann Kirsten , Masharani Umesh , Yeboah Joseph , Park Meyeon , Li Lihua , Weber Ellerie , Li Yan , Berkalieva Asem , Max Wendy , Hunink Myriam , S. Ferket Bart
Published: May 2023

  

Objective

Eligibility for glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) has been expanded to patients with diabetes at lower cardiovascular risk, but it is not clear whether expected treatment benefits differ by risk levels. We investigated whether patients with varying risks differ in cardiovascular and renal benefits from GLP-1RAs and SGLT2i using meta-analysis and meta-regression. 

Research Design and Methods

We updated searches of recent meta-analyses using PubMed through November 7, 2022. We included reports of confirmatory randomized trials of GLP-1RA and SGLT2i in adult patients with safety or efficacy endpoint data. We extracted hazard ratio (HR) and event rate data for mortality, cardiovascular, and renal outcomes.

Results

We analyzed 9 GLP-1RA and 13 SGLT2i trials comprising 154,649 patients. Summary HRs were significant for cardiovascular mortality (GLP-1RA: 0.87; SGLT2i: 0.86), major adverse cardiovascular events (0.87; 0.88), heart failure (0.89; 0.70), and composite renal (0.84; 0.65) outcomes. For stroke, efficacy was significant for GLP-1RAs (0.84), but not for SGLT2i (0.92). We did not find statistically significant associations between control arm cardiovascular mortality rates and HRs. Five-year absolute risk differences ranged from -4.25% to -0.80%, with larger reductions (11.6%) for heart failure with SGLT2i in high risk (p for slope <.001). For GLP1-RAs, associations were nonsignificant.

Conclusions

Relative effects of novel diabetes drugs are preserved across baseline cardiovascular risk, whereas absolute benefits increase at higher risks, particularly regarding heart failure. Our findings suggest a need for baseline risk assessment tools to identify variation in absolute treatment benefits and improve decision-making. 