bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ECO-LOGISTICAL SYSTEM PROJECT STATIONARY STATE METABOLISM MODEL
Authors:   Odessa National Maritime University, Kovtun Тetiana А. , Finohenova Iryna O. ,   Odessa National Maritime University
Published: January 2023

At the present stage of human evolution, achieving the goals of sustainable development is an important task of the global agenda. Man-made type of economy for centuries before the ecological crisis, as it was unable to ensure balanced civilization without harming the environment. Search for new ways of human development called for the emergence of modern economic models and systems, including environmentally-oriented logistics systems. This will minimize the negative impact on the environment that meets the environmental objectives of the Concept of Sustainable Development.The aim of the article is to form a model of steady state metabolism of the ecological system project.The article uses the tools of methodologies of design, logistics and environmental management; systemic as general-managerial and physical as scientific-natural approaches are applied for the characteristic of stationary states of the project of ecological system.The article presents a model of the ecological system project as a complex open dynamic system related to the supra-biological level of the organization, as it consists of many elements that form the internal environment of the project (complex) and are interconnected with the elements of the external environment. Сhanges its state during the life cycle of the project (dynamic) and maintains a dynamic relative constancy of composition and properties (stationary).The design of the ecological system in order to maintain the homeostasis of the system carries out the metabolism with the design environment, removing resources, transforming them and returning them to the environment. The steady state of the ecological system project is described using a metabolism model.A mathematical model of steady-state metabolism of the ecological system project has been developed.Keywords:еcological system project, project life cycle, metabolism model, steady state of the project. DEVELOPMENT
Building A Muslim Worldview Through Islamic Education in The Middle of Globalization
Authors: Husna Arinal , Mahfuds Yusqi , Uthman Yusuf Olawale Owa-Onire , Aprilianto Andika
Published: January 2023

It is undeniable that the current of westernization has been so strong. Western cultural values ​​and ideologies have entered the minds of most Indonesian Muslims. So unknowingly, he became a worldview. This study aims to examine two things; first. The importance of the Islamic worldview for a Muslim as a feature of his identity in the midst of globalization, and secondly. The role of Islamic education in building and linking the world view of Islam in Muslim societies in the midst of globalization. This research includes library research, so the data collection technique used in this research is literary data collection. The results of this study show that the Islamic worldview is very different from the western worldview regarding reality and truth because the Islamic worldview refers to the main sources, namely the Qur'an and Hadith. For this reason, the role and responsibility of Islamic education are to build and strengthen the worldview of Islam in Muslim society as a system of guidance and control over ideas and values ​​that undermine their identity or identity as Muslims. The education system must refer to the Islamic worldview to produce pious human beings who always base their attitudes and actions on Islamic teachings and values.
Fiqh Criticism According to the Malikis: Its Fields and Kinds
Authors: Elalaoui Mustapha Elhassani
Published: January 2023

In this research, I dealt with the issue of Fiqh criticism according to the Malikis, its fields and its divisions, and I combined through it three essential issues. The first is Fiqh, juristic, criticism as a compact contemporary term, and I showed that the early jurists practiced criticism in their works, but they replaced it with words including: evaluation, refinement, pruning, and so on. As for the contemporaries, they tried to approach its meaning by referring to the works of their predecessors to extract its connotations. The second of them are its fields, and through it I have roamed in the fields of knowledge that were touched by the criticism of the Malikis. It is used by the scholars of the sect in its scrutiny of its origins and branches in order to strengthen its structure methodologically and cognitively, and to respond to the allegations and suspicions of other sects.
The Trans- Ummah, the Extended State, and the Question of Universality (A study in the Meanings of the Quranic Texts)
Authors: Amezzian Mohammed
Published: January 2023

The central idea around which this paper rotates is that there is- in the Islamic perspective of political sociology- a mutual relationship between the Ummah and the state. The assumption here is that the essential characteristics of the state stem from the characteristics of the Ummah. As a demographic, extra-territory, timeless and multi-ethnical, all is such an embracing Ummah that stands as the constituent domain of the state as well as its social incubator. Likewise, the state as a material entity- with a legal status- stands as an embodiment of the Ummah. This would also make it a kind of an extended state the boundaries of which end only where its demographic extension ends. To prove this hypothesis, we attempt in this paper to discern the meanings of the Qur’anic texts that are relevant to this setting. The analysis will proceed through two integrated themes: the first one looks into the textual meanings that portrays the existence of an Ummah- united around a doctrinal identity that serves as a melting pot for nationalistic, linguistic, and relativistic ties. The second theme looks into textual meanings that indicate the emergence of an Ummah- upholding a political program, which transcends geographical borders, and promises victory and firm establishment on the land.
Proliferating Trichilemmal Tumor, A Systemic Review
Authors: Faraji Rad Mohammad
Published: January 2023

Background:Malignant proliferating trichilemmal tumor is a rare skin tumor that affects mainly older women. It similar to differential squamous cell carcinoma. Methods: A search strategy was designed and run in Medline and google scholar. Also, searching grey literature, checking references, tracking citations, hand-searching of focused journals, and websites were utilized for retrieval of related studies. All of articles which studied epidemiology of mortality or injuries of the war were included. Conclusion:Malignant proliferating trichilemmal tumours are rare and cause struggling in diagnosis for the surgeon ‎‎as there is a high risk of recurrence and metastasis‎
CURRENT STATE AND LEVEL OF ACHIEVEMENT OF SUSTAINABLE DEVELOPMENT GOALS IN THE SIBERIAN FEDERAL DISTRICT: ENVIRONMENTAL ASPECT
Authors: Ryumkina I. N. , Ryumkin S. V. , Imeskenova E. G. , Dorzhieva A. S.q
Published: January 2023

he authors in the article presented an overview of the sustainable development goals in the field of “ecology” for individual countries of the world and the Siberian Federal District of the Russian Federation (SFD). The purpose of the study is to analyze the achievement of the Sustainable Development Goals (SDGs) in rural areas in SFD regions at the moment according to the indicators presented by U.N. General Assembly resolution A/RES/70/1. In addition, the authors considered the factors influencing the achievement of the SDGs. The research methods were retrospective and statistical analyses. Furthermore, the study also examined indirect determinants, year by year, that affect the development of the SDGs in the regions. Finally, the study presents proposals for optimizing the environmental situation in SFD subjects and the effective management of measures to achieve the SDGs.
EVALUATION OF THE ACTION OF BIOAGENTS AGAINST STRAWBERRY HELMINTHIASIS
Authors: Belyaev A. A. , Storozhenko A. A. , Shpatova T. V.
Published: January 2023

In 3-year field model experiments on 2 plots of a strawberry production plantation: populated with a stem strawberry nematode and free from a nematode, it was found that pre-planting treatment of the root system of seedlings with fungal and bacterial strains of bioagents by the fungi Arthrobotrys oligospora VKPM F-1141 and Duddingtonia flagrans VKM F-2574 , as well as a mixed biopreparation Fitop 18.81 hasa protective effect against plant damage by a nematode disease with a biological efficiency of 37-49 %. The length of the roots significantly increased in the variants with the treatment with the strain Duddingtonia flagrans VKM F-2574 and the mixed preparation Fitop 18.81 - by 15.7 and 11.5 %, respectively. Against the background free from nematodes in the variants with preplant treatment with Arthrobotrys oligospora strain VKPM F-1141 and Fitop 18.81, effective stimulation of the number of daughter rosettes by 36.7-39.1 % was proved. The studied bioagents are promising as prophylactic anti-nematode agents when laying fruit-bearing and uterine strawberry plantations.
THE EFFECT OF FACTORS ON TAX AVOIDANCE IN BANKING COMPANIES LISTED ON THE INDONESIA STOCK EXCHANGE
Authors: Sukendar Heri , Djaja Irwan , Mettaya Viani
Published: January 2023

Abstract - This study aims to examine and obtain empirical evidence about the effect of gender diversity, characteristics of executives, CEO narcissism, profitability, and firm size on tax avoidance in Indonesia public listed banking companies over the period 2015-2020. Using a purposive sampling method, the sample selected in this study is 83 samples. Multiple linear regression analysis examines the effect of independent variables on the dependent variable. This study shows that gender diversity and profitability have significant effects on tax avoidance. Meanwhile, the characteristics of executives, CEO narcissism, and firm size has no significant impact on tax avoidance.

Keywords: Tax Avoidance; Gender Diversity; Characteristics of Executives; CEO Narcissism, Profitability; Firm Size
Cancel Culture : Case Study of Sexual Harassment on Followers Autobase Twitter @Areajulid
Authors: Nisa Yayang Eka Januarda , . Yuhastina , Nurhadi Nurhadi
Published: January 2023

Virtual open spaces such as Twitter offer a place for netizens to gather and discuss certain topics. Netizens will issue their own opinions and often end up boycotting/punishing someone who is considered to have made a mistake, which is called cancel culture, experts have different opinions about cancel culture. This study attempts to provide an overview from the field regarding the phenomenon of cancel culture in cases of sexual violence as part of a social control. This study uses a phenomenological qualitative method, the data is taken from the results of interviews and observations to 7 followers of the @AREAJULID autobase account. The results of the study concluded that 1) The informants canceled the perpetrators of sexual violence in different ways. 2) Cancel culture is a means of social control through rumors and gossip.
Improving Civic Engagement through “No Viral No Justice” Phenomenon
Authors: Grecya Elsa , Yahya Ilham Effendi
Published: January 2023

Penelitian ini bertujuan untuk menganalisis ruang publik yang secara tidak langsung terbuka untuk masyarakat ikut mempengaruhi jalannya hukum. Metode penelitian ini dilaksanakan dengan metode riset kepustakaan. Sumber data yang digunakan adalah sumber data sekunder berupa jurnal dan artikel berita online. Hasil penelitian menunjukan bahwa kepolisian dianggap gagal menjalankan perannya sebagai pelayanan dan pelindung masyarakat. Fenomena no viral no justice menjadi hantaman keras kepada Kepolisian Republik Indonesia. Kapolri Jenderal Pol Listyo rasanya mengakui bahwasanya tagar no viral no justice bukan sekedar tagar iseng. Listyo Sigit Prabowo meminta jajarannya untuk menjadikan fenomena ini sebagai bagian kritik dari masyarakat terhadap kepolisian. Listyo mengimbau agar fenomena terkait kepolisian tidak terulang. Dia meminta staf mengevaluasi dan memperbaiki diri dalam melayani masyarakat. Listyo mengingatkan bahwa semua penilaian publik harus diterima sebagai bagian dari kritik dan penilaian polisi. Selain hal tersebut, secara tidak langsung fenomena no viral no justice membuka ruang publik alternatif melalui media sosial. Ruang publik tersebut dimanfaatkan masyarakat sebagai opinion leader dari masyarakat yang secara tidak langsung membentuk civic engagement berdasarkan rasa kasihan terhadap korban dan kecewa terhadap kepolisian yang gagal dalam menjalankan tugasnya.
ON THE ISSUE OF EARLY POSTOPERATIVE COMPLICATIONS IN A MULTIDISCIPLINARY ONCOLOGICAL HOSPITAL (LITERATURE REVIEW)
Authors:   Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic named after prof. M.Z. Sigal, Mingalimova E. Yu. , Zinchenko S. V. ,   Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic named after prof. M.Z. Sigal, Khasanov R. Sh. ,   Kazan State Medical Academy ― Branch Campus of the FSBEI FPE RMACPE MOH Russia, Khaertdinov L. I. ,   Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic named after prof. M.Z. Sigal
Published: January 2023

The purpose of this review was the need to study early postoperative complications in cancer patients after surgical interventions. The article analyzes the existing sources of literature on the declared issue. Numerous studies by domestic and foreign authors concern only narrow technical aspects, without touching on key issues of reducing the risk of postoperative complications. These circumstances determine the relevance of conducting comprehensive studies on the formation of a vector of systemic measures aimed at reducing postoperative complications and associated mortality and disability of patients with malignant neoplasms.
CLINICAL AND MORPHOLOGICAL FEATURES OF MOLECULAR-GENETIC CLUSTERS IN TRIPLE NEGATIVE BREAST CANCER
Authors:   Ulyanovsk State University, Panchenko I. S. , Rodionov V. V. ,   National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Acad. V.I. Kulakov, Burmenskaya O. V. ,   National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Acad. V.I. Kulakov, Kometova V. V. ,   National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Acad. V.I. Kulakov, Bozhenko V. K. ,   Russian Scientific Center of Roentgenoradiology, Sharafutdinov M. G. ,   Ulyanovsk State University, Panchenko S. V. ,   Ulyanovsk State University, Matveeva L. V. ,   Ulyanovsk State University
Published: January 2023

Breast cancer is the most common malignant tumors in women in the world. One of most unfavorable biological breast subtype ― is the triple negative breast cancer (TNBC). It occurs in young age, and characterized high rate of locoregional rates and distant metastases. Currently, according to molecular genetic profiling, TNBC ― is a group of tumors with different prognosis, course and response to treatment. In our study we analyzed the molecular genetic profiling of 246 cases of triple negative breast cancer. 45 genes were included in our gene signature. Using K-means clustering method, it was possible to identify 4 tumor clusters with different clinical and morphological features. The most indicative were patients of clusters 2 and 3, since it was in these clusters that most of the proposed genes were overexpressed. Cluster 1 characterized by hypoexpression of most genes, while patients of 4 cluster characterized average values of most genes. Each of resulting clusters had «molecular genetic» portrait, which provided information about the predominance of certain signaling pathways in the tumor, the impact of which can be used as an additional option in the treatment of patients with TNBC. It was possible to identify clinical and morphological features that were statistically significantly different (p≤0,05) in the presented molecular genetic clusters: clinical stage, status of regional lymph nodes, histological subtype, degree of tumor differentiation, Ki67 level. In addition, when we comparing the immunohistochemical (IHC) subtype of the tumor with the molecular type of the tumor, it turned out that the most heterogeneous cluster was the cluster 4, in which only 64,1% of tumors were true triple negative. Thus, molecular genetic profiling of triple negative breast cancer, in our opinion, should be considered as a perspective diagnostic method for this disease, as it will help to choose a correct and personalized treatment for an individual patient.
Platelet count and breast cancer stage
Authors: Fahdrin Andi , Sampepajung Elridho , Pieter John , Kasim Firdaus , Smaradhania Nilam , Prihantono Prihantono , Mariana Nita , Sampepajung Daniel , Faruk Muhammad
Published: January 2023

INTRODUCTION: The relationship between increased platelet count and cancer classification stage has long been established. The prevalence of thrombocytosis varies from 10% to 57% in cancer patients. The pathogenesis of thrombocytosis in malignancy is uncertain. However, there is evidence that tumor cells secrete humoral factors that can cause thrombocytosis. Preoperative thrombocytosis is a poor prognostic variable in malignancies. This study investigated the correlation between platelet count and breast cancer stage. METHODS: This cross-sectional study was conducted from February 2020 to January 2021. Patient data were collected from medical records. The study population comprised breast cancer patients at Dr. Wahidin Sudirohusodo Makassar. The staging examinations were based on the tumor, node, metastasis (TNM) classification according to the American Joint Committee on Cancer (AJCC) 8th Edition. RESULTS: The study group comprised 171 breast cancer patients of varying ages. Metastasis was present in five (2.92%) patients and absent in 166 (97.8%) patients. Analyses found no statistically significant differences between the three staging groups based on the platelet count (p = 0.952). CONCLUSION: There was no statistically significant relationship between increased platelet count and staging according to the TNM classification in breast cancer patients.
Experimental assessment of link slabs in continuous span applications of press-brake-formed tub girders
Authors: Barth Karl E. , Michaelson Gregory K. , Tennant Robert M. , Woldegabriel Brook
Published: January 2023

The scope of this effort is to evaluate the performance of a link slab transversely connecting press-brake-formed tub girders (PBFTG). Modular PBFTGs were developed by a technical working group within the Steel Market Development Institute’s (a business unit of the American Iron and Steel Institute) Short Span Steel Bridge Alliance, led by the current authors. This working group consists of stakeholders in the steel bridge industry, including mills, fabricators, service centers, industry trade organizations, universities, and bridge owners. A full-scale link slab transversely joining two PBFTGs was fatigue loaded simulating a 75-year fatigue life in a rural environment. Strain and deflection data was recorded and compared throughout the fatigue life to determine the link slab’s effectiveness. Results of this effort show the link slab detail performs adequately throughout its fatigue life.
Systematic Review of EEG Coherence in Alzheimer’s Disease
Authors: Fischer Michael Hén Forbord , Zibrandtsen Ivan Chrilles , Høgh Peter , Musaeus Christian Sandøe
Published: January 2023

Background: Magnitude-squared coherence (MSCOH) is an electroencephalography (EEG) measure of functional connectivity. MSCOH has been widely applied to investigate pathological changes in patients with Alzheimer’s disease (AD). However, significant heterogeneity exists between the studies using MSOCH. Objective: We systematically reviewed the literature on MSCOH changes in AD as compared to healthy controls to investigate the clinical utility of MSCOH as a marker of AD. Methods: We searched PubMed, Embase, and Scopus to identify studies reporting EEG MSCOH used in patients with AD. The identified studies were independently screened by two researchers and the data was extracted, which included cognitive scores, preprocessing steps, and changes in MSCOH across frequency bands. Results: A total of 35 studies investigating changes in MSCOH in patients with AD were included in the review. Alpha coherence was significantly decreased in patients with AD in 24 out of 34 studies. Differences in other frequency bands were less consistent. Some studies showed that MSCOH may serve as a diagnostic marker of AD. Conclusion: Reduced alpha MSCOH is present in patients with AD and MSCOH may serve as a diagnostic marker. However, studies validating MSCOH as a diagnostic marker are needed.
Insomnia Symptoms and Biomarkers of Alzheimer’s Disease in the Community
Authors: Nicolazzo Jessica , Cavuoto Marina , Rowsthorn Ella , Cribb Lachlan , Bransby Lisa , Gibson Madeline , Wall Prudence , Velakoulis Dennis , Eratne Dhamidhu , Buckley Rachel , Yassi Nawaf , Yiallourou Stephanie , Brodtmann Amy , Hamilton Garun S. , Naughton Matthew T. , Lim Yen Ying , Pase Matthew P.
Published: January 2023

Background: Insomnia is one of the most common sleep disorders yet its relationship to the biology of Alzheimer’s disease remains equivocal. Objective: We investigated the cross-sectional relationship between insomnia symptom severity and cerebrospinal fluid (CSF) concentrations of Alzheimer’s disease biomarkers in a cognitively unimpaired middle-aged community sample. Methods: A total of 63 participants from the Healthy Brain Project (age = 59±7 years; 67% women) completed a lumbar puncture and two weeks of actigraphy to measure two of insomnia’s core features: difficulty initiating sleep (prolonged sleep onset latency) and difficulty maintaining sleep (wake after sleep onset [WASO] and number of awakenings). Additionally, the Insomnia Severity Index (ISI) was completed by 58 participants. Linear and Tobit regression were used to estimate the associations between each insomnia variable and CSF Aβ42, phosphorylated tau 181 (p-tau181), total-tau, and neurofilament light chain protein (NfL), adjusting for age, sex, and APOE ɛ4 genotype. Results: Higher ISI score was associated with greater average levels of CSF Aβ42 (per point: 30.7 pg/mL, 95% CI: 4.17–57.3, p = 0.023), as was higher WASO (per 10 min: 136 pg/mL, 95% CI: 48–223, p = 0.002) and more awakenings (per 5:123 pg/mL, 95% CI = 55–192, p < 0.001). Difficulty initiating sleep was not associated with CSF Aβ42, nor were insomnia features associated with p-tau181, total-tau, or NfL levels. Conclusion: Insomnia symptoms were associated with higher CSF Aβ42 levels in this relatively young, cognitively unimpaired sample. These findings may reflect increased amyloid production due to acute sleep disruption.
Helicobacter pylori Infection Is Associated with Long-Term Cognitive Decline in Older Adults: A Two-Year Follow-Up Study
Authors: Wang Jian , Yu Neng-Wei , Wang Duo-Zi , Guo Lei , Yang Shu , Zheng Bo , Guo Fu-Qiang , Wang Jian-Hong
Published: January 2023

Background: Previous cross-sectional studies have identified a possible link between Helicobacter pylori (H. pylori) infection and dementia. However, the association of H. pylori infection with longitudinal cognitive decline has rarely been investigated. Objective: This cohort study aims to demonstrate the effects of H. pylori infection on longitudinal cognitive decline. Methods: This cohort study recruited 268 subjects with memory complaints. Among these subjects, 72 had a history of H. pylori infection, and the rest 196 subjects had no H. pylori infection. These subjects were followed up for 24 months and received cognitive assessment in fixed intervals of 12 months. Results: At baseline, H. pylori infected, and uninfected participants had no difference in MMSE scores. At 2 years of follow-up, H. pylori infected participants had lower MMSE scores than uninfected participants. H. pylori infection was associated with an increased risk of longitudinal cognitive decline, as defined by a decrease of MMSE of 3 points or more during follow-up, adjusting for age, sex, education, APOE ɛ4 genotype, hypertension, diabetes, hyperlipidemia, and smoking history (HR: 2.701; 95% CI: 1.392 to 5.242). H. pylori infection was associated with larger cognitive decline during follow-up, adjusting for the above covariates (standardized coefficient: 0.282, p < 0.001). Furthermore, H. pylori infected subjects had significantly higher speed of cognitive decline than uninfected subjects during follow-up, adjusting for the above covariates. Conclusion: H. pylori infection increases the risk of longitudinal cognitive decline in older subjects with memory complaints. This study is helpful for further understanding the association between infection and dementia.
Screening for possible hypopituitarism following mild traumatic brain injury: The first all-female study. Who do we need to evaluate further?1
Authors: Claessen Lára Ósk Eggertsdóttir , Kristjánsdóttir Hafrún , Jónsdóttir María K. , Lund Sigrún Helga , Kristensen Ingunn S.U. , Sigurjónsdóttir Helga Ágústa
Published: January 2023

BACKGROUND: Studies on hypopituitarism (HP) following mild traumatic brain injury (mTBI) have focused on male populations although women may be more susceptible to the sequelae of mTBI. This is, to the best of our knowledge, the first all-female study screening for HP following mTBI. OBJECTIVE: Screening for possible HP in female athletes reporting a history of one or more mTBI. METHODS: Pituitary hormone screening blood tests (SBT) were performed in 133 of the 151 female athletes included. Repeated results outside the reference value (O-RV) were considered abnormal necessitating further endocrinological evaluation. RESULTS: Repeated SBT were O-RV in 88 women (66.2%). Decreased levels of serum insulin growth factor 1 (S-IGF1) were found in 55.6% of participants and elevated levels of serum prolactin (S-prolactin) in 22.6%. Serum cortisol levels were below the RV in 6.0% and thyroid hormonal levels in 11.3%. Lower age and increased number of mTBI symptoms correlated significantly with the risk of hormonal results O-RV. CONCLUSION: The majority of the study population had SBT O-RV, warranting further workup of possible HP. Decreased levels of S-IGF1 were most commonly observed followed by elevated S-prolactin possibly indicating hypothalamic-pituitary impairment. Lower age and increased number of symptoms of mTBI may indicate the need to screen for HP.
Design, fabrication and experiments of a hydraulic active-passive hybrid prosthesis knee
Authors: Li Zhennan , Liu Chunbao , Han Yang , Wang Tongjian , Lei Ren
Published: January 2023

BACKGROUND: Due to low friction, passive mechanical prostheses move compliantly followed by the stump and are used widely. Advanced semi-active prostheses can both move passively like passive prostheses and provide active torque under specific conditions. However, the current mechanical-hydraulic coupling driven semi-active prostheses, in order to meet the low passive friction requirements with a low active transmission ratio, lead to a significant problem of insufficient active torque. OBJECTIVE: A hybrid active and passive prosthesis was developed to solve the incompatibility problem of low passive friction and high active driving torque of semi-active prostheses. METHODS: The mechanical structure and control strategy of the prosthesis were demonstrated. The performance of the prosthesis was tested by bench and human tests. RESULTS: Passive subsystem damping adjustment ranges from 0.4 N⋅(mm/s)-1 to 300 N⋅(mm/s)-1. The switching time between the damping and the active subsystem is 32 ± 2 ms. The continuous active torque output is more than 24 Nm. In level walking, the peak torque is about 28 Nm. CONCLUSION: The proposed active-passive hybrid hydraulic prosthesis could satisfy both low passive friction and high active actuation.
DentaSeal: A school-based dental sealant efficiency assessment tool to support statewide monitoring and reporting: A field report
Authors: Shimpi Neel , Glurich Ingrid , Hegde Harshad , Steinmetz Annie , Kuester Robbyn , Crespin Matthew , Acharya Amit
Published: January 2023

BACKGROUND: The evidence base supports effectiveness of dental sealants for prevention of childhood caries in school-aged children. OBJECTIVE: This study describes planning, development, usability testing and outcomes following implementation of DentaSeal, a web-based application designed to accurately track unique student data and generate reports for all Wisconsin school-based sealant placement (SP) programs. METHODS: Application software development was informed by a steering committee of representative stakeholders who were interviewed to inform design and provide feedback for design of DentaSeal during development and evaluation. Software development proceeded based on wireframes developed to build architectural design. Usability testing followed and informed any required adjustments to the application. The DentaSeal prototype was beta tested and fully implemented subsequently in the public health sector. RESULTS: The DentaSeal application demonstrated capacity to: 1) track unique student SP data and longitudinal encounter history, 2) generate reports and 3) support administrative tracking. In 2019, DentaSeal captured SP data of 47 school-based programs in Wisconsin that sponsored > 7,000 program visits for 184,000 children from 62 counties. Delivery of > 548,000 SP services were catalogued. CONCLUSIONS: For public health initiatives targeting reduction in caries incidence, web-based applications such as DentaSeal represent useful longitudinal tracking tools for cataloguing SP in school-based program participants.
Heat-not-burn tobacco products and cardiovascular risk reduction: A systematic review of randomized controlled trials
Authors: Begić Edin , Aziri Buena , Omeragić Elma , Medjedović Edin , Iglica Amer , Stanetić Bojan , Kovačević-Preradović Tamara , Živanović Željko , Begić Amra , Janković Slobodan , Mlačo Nejra , Mladenović Zorica , Badnjević Almir
Published: January 2023

BACKGROUND: Heat-not-burn (HNB) technology by the U.S. Food and Drug Administration has been classified as a modified risk tobacco product, which can be a better option for those populations who cannot give up the habit of smoking. The outlook on the effects of these products is quite controversial in the scientific world. OBJECTIVE: To present the effect of HNB tobacco products on the cardiovascular system, with reference to the existence of possible benefits of the technology. METHODS: The literature search was conducted in PubMed/Medline, the Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov databases, with reliance on a well-defined guiding research statement. Quality appraisal was performed using the CASP checklist for randomized controlled trials. RESULTS: The search of three databases identified 167 records, and after selection process, 25 randomized controlled trials were eligible for our study’s criteria. Twenty studies investigated the effects of HNB products on biomarkers of clinical relevance. Five studies evaluated other functional heart parameters rather than biomarkers. CONCLUSION: With HNB tobacco products, significant reductions were found in biomarkers of exposure and biological effect related to pathways involved in cardiovascular disease, including inflammation, oxidative stress, lipid metabolism, platelet function, and endothelial dysfunction.
Mechanism of andrographis paniculata on lung cancer by network pharmacology and molecular docking
Authors: Li Jiaxin , Liu Xiaonan , Li Jiaxin , Han Dongwei , Li Yu , Ge Pengling
Published: January 2023

BACKGROUND: Traditional Chinese medicine (TCM) has been widely recognized and accepted worldwide to provide favorable therapeutic effects for cancer patients. As Andrographis paniculata has an anti-tumor effect, it might inhibit lung cancer. OBJECTIVE: The drug targets and related pathways involved in the action of Andrographis paniculata against lung cancer were predicted using network pharmacology, and its mechanism was further explored at the molecular level. METHODS: This work selected the effective components and targets of Andrographis paniculata against the Traditional Chinese Medicine System Pharmacology (TCMSP) database. Targets related to lung cancer were searched for in the GEO database (accession number GSE136043). The volcanic and thermal maps of differential expression genes were produced using the software R. Then, the target genes were analyzed by GO and KEGG analysis using the software R. This also utilized the AutoDock tool to study the molecular docking of the active component structures downloaded from the PubChem database and the key target structures downloaded from the PDB database, and the docking results were visualized using the software PyMol. RESULTS: The results of molecular docking show that wogonin, Mono-O-methylwightin, Deoxycamptothecine, andrographidine F_qt, Quercetin tetramethyl (3’,4’,5,7) ether, 14-deoxyandrographolide, andrographolide-19-β-D-glucoside_qt and 14-deoxy-11-oxo-andrographolide were potential active components, while AKT1, MAPK14, RELA and NCOA1 were key targets. CONCLUSION: This study showed the main candidate components, targets, and pathways involved in the action of Andrographis paniculata against lung cancer.
Competence development as critical issue for successful performance in HPC technology environment: A case study of Montenegro
Authors: Malisic Bojana , Tinaj Sandra
Published: January 2023

BACKGROUND: Absorptive capacity is the ability to absorb new knowledge and adopt new technologies. This capacity of an economy is measured through a series of indicators, however, the most important among them are precisely those elements related to the competences required for the adoption of new technologies, as well as their structure. OBJECTIVE: This paper provides an overview of the concepts and systems needed to develop the competencies needed to implement modern technology such as High-Performance Computing (HPC) in Montenegro. METHOD: In this research paper competencies are viewed holistically. This paper will elaborate the defined competencies related to the HPC technology environment, identified during the implementation of the EuroCC project in Montenegro, but also based on market analyses, combined with the identified indicators of absorption capacity, generally at the national level. RESULT: By identifying the innovative and business potential of representatives of the public, academic and economic sectors, with special reference to small and medium-sized companies and the IT cluster that make up the dominant segments in the structure of the market sample, as generators and accelerators of innovation, smart growth and the digital economy, we got a clear picture regarding the development of necessary competencies within the NCC team but also at the national level. CONCLUSION: There must be a systemic approach and sustainable, dynamic projects and tools for the development of human resources in the development of competences.
Successful pregnancy and delivery outcome after the surgical treatment of pituitary adenoma in the first trimester of pregnancy (a clinical case)
Authors:   City Clinical Hospital No. 52, Moscow, Russian Federation, Barakina O.V , Markova T.N. ,   City Clinical Hospital No. 52, Moscow, Russian Federation,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation, Ismailova S.G. ,   City Clinical Hospital No. 52, Moscow, Russian Federation, Godkov I.M. ,   Moscow Multi-profile Clinical Center "Kommunarka," Moscow, Russian Federation,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Grabovsky V.M. ,   City Clinical Hospital No. 52, Moscow, Russian Federation, Kozlov P.V. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: January 2023

The authors present a clinical case of partial hypopituitarism developed in a 31-year-old patient during the first trimester of pregnancy after the surgical treatment of hemorrhagic pituitary adenoma. The onset of the diseases was recorded on the 12th week of pregnancy and was characterized by such specific clinical manifestations as severe headache, multiple spells of vomiting, diplopia and right-sided ptosis. The contrast-enhanced MRI revealed a pituitary adenoma with a "fresh" hemorrhage and the destruction of anterior wall and floor of the sella turcica, and the invasion into the sphenoid and right cavernous sinuses. The patient underwent emergency surgery – the endoscopic endonasal approach for total resection of pituitary adenoma. Hypopituitarism manifestations identified in the postoperative period were relieved by hormone replacement therapy. A timely diagnosis and prompt decision on the surgical treatment of pituitary adenoma, as well as a multidisciplinary team approach to patient care ensured the appropriate management of the underlying disease, successful pregnancy, childbirth outcome and high maternal quality of life. KEYWORDS: pituitary adenoma, pregnancy, management practices, hemorrhage, pituitary apoplexy, hypopituitarism, surgical treatment. FOR CITATION: Barakina O.V., Markova T.N., Ismailova S.G. et al. Successful pregnancy and delivery outcome after the surgical treatment of pituitary adenoma in the first trimester of pregnancy (a clinical case). Russian Journal of Woman and Child Health. 2022;5(4):326–331 (in Russ.). DOI: 10.32364/2618-8430-2022-5-4-326-331.
Efficiency of presowing seed treatment of Vigna unguiculata subsp. sesquipedalis, Triticum aestivum L., Raphanus sativus L., Allium cepa L. with silicon oxide
Authors: Lekonceva Tat'yana , Fedorov Aleksandr
Published: January 2023

Abstract. The purpose of the study was to test the effect of an aqueous solution of silicon oxide on the sowing qualities of plant seeds. Methods. The assessment of the effect of silicon oxide (SiO2) on the sowing qualities of seeds was carried out by a laboratory method according to Medical and biological safety assessment of nanomaterials 1.2.2635-10 and GOST 12038-84 “Seeds of agricultural crops. Methods for determining germination”. Asparagus bean seeds Vigna unguiculata subsp. sesquipedalis of Matilda variety, spring wheat Triticum aestivum L. of Svecha variety, seed radish Raphanus sativus L. of Champion variety and onion Allium cepa L. of Odintsovo variety. The following indicators were taken into account: germination energy and seed germination, number, length and weight of underground and aboveground parts of seedlings. Statistical data processing was carried out by the dispersion method according to B. A. Dospekhov. Scientific novelty. The species-specific reaction of seeds to the treatment with silicon oxide was revealed. The best results in terms of morphometric parameters of seedlings of asparagus bean and spring wheat were obtained when seeds were treated with 0.0025 % silicon oxide, radish – 0.005 %. It is not advisable to treat onion seeds with silicon oxide. According to the research results, asparagus bean seeds turned out to be the most responsive to processing. Germination energy and seed germination in the variant of treatment with 0.0025 % silicon oxide compared to the control (distilled water) were 13.7 % and 3.0 % higher, respectively, but the difference is not significant. The studied concentrations contributed to a significant increase in the average length of the roots. At 0.01 % concentration, this indicator was higher by 30.6 mm, 0.005 % by 30.7 mm, at 0.0025 % by 48.8 mm, respectively (HCP05 = 30.1). The average root weight was 67.5 mg more in the variant of seed treatment with 0.0025% silicon oxide solution (HCP05 = 41.5).
2019–2020 Florida Citrus Production Guide: Quick Reference Guide to the Worker Protection Standard (WPS)
Authors: Fishel Frederick
Published: January 2023

The Worker Protection Standard (WPS) is a regulation originally issued by the US Environmental Protection Agency (EPA) in 1992 and most recently revised in 2015. This regulation is primarily intended to reduce the risks of illness or injury to workers and pesticide handlers resulting from occupational exposures to pesticides used in the production of agricultural plants on agricultural establishments (i.e., farms, forests, nurseries, and enclosed-space production facilities such as greenhouses). This 8-page fact sheet is part of the 2019–2020 Florida Citrus Production Guide. Written by Frederick M. Fishel and published by the Entomology and Nematology Department, March 2019.
CPMG-07/CG036: 2022–2023 Florida Citrus Production Guide: Quick Reference Guide to the Worker Protection Standard (WPS) (ufl.edu)
Preventing Escape of Non-Native Species from Aquaculture Facilities in Florida, Part 4: Operational Strategies
Authors: Tuckett Quenton M. , Martinez Carlos V. , Ritch Jared L. , Lawson Katelyn M. , Hill Jeffery E.
Published: January 2023

Structural strategies to prevent the escape of non-native species from aquaculture facilities have numerous environmental benefits, and research at the UF/IFAS Tropical Aquaculture Laboratory has shown that structural strategies also reduce non-compliance with Florida Department of Agriculture and Consumer Services Best Management Practices. Operational and management strategies, however, are also very important. The strategies discussed in this 6-page fact sheet, the management of water, facilities, and employees, must not be overlooked. Operational strategies are easy, inexpensive, and, when used alongside structural strategies, highly effective, offering an impressive return on a minimal investment in the overall effort to minimize the escape of non-native species.
This fact sheet is the fourth in a four-part series devoted to educating industry and other stakeholders on the importance of preventing escape of non-native species from aquaculture facilities, as well as strategies for non-native species containment and regulatory compliance. Written by Quenton M. Tuckett, Carlos V. Martinez, Jared L. Ritch, Katelyn M. Lawson, and Jeffrey E. Hill, and published by the School of Forest Resources and Conservation, Program in Fisheries and Aquatic Sciences, August 2016.
FA198/FA198: Preventing Escape of Non-Native Species from Aquaculture Facilities in Florida, Part 4: Operational Strategies (ufl.edu)
Overview of US Tahiti Lime Production and Markets: Trade and Consumption Analysis
Authors: Blare Trent , BALLEN Fredy , Crane Jonathan
Published: January 2023

Key and Tahiti limes have historically been very important to the economy of south Florida. However, there are few commercial orchards left for these lime cultivars in the state. Many orchards were destroyed during Hurricane Andrew, and those that survived were then eliminated by Florida’s Citrus Canker Eradication Program in the late 1990s and early 2000s. Tahiti limes are being considered for reintroduction in Miami-Dade County because of the growing demand for this fruit, especially among buyers who are willing to pay more for Florida-grown fruit. In this publication, we explore the history of lime production in south Florida and current trends in the market, especially growing demand in the United States for Tahiti limes. The price premiums from the growing domestic market for Tahiti limes would likely be enough to overcome the challenges growers face in combating the disease pressure from citrus canker, citrus greening, and intense competition from Mexico and other countries.
Chayote—A Potential Vegetable Crop for Florida
Authors: Qiu Yuheng , Liu Guodong
Published: January 2023

Chayote, known as the vegetable pear, is a nutritious plant with a pale-green, ridged, fleshy fruit with a single seed. Florida’s suitable climate combined with chayote’s excellent taste and nutrition indicate that it could be an economically viable crop for commercial production. The intended audience of this new 10-page publication of the UF/IFAS Horticultural Sciences Department is vegetable growers, Extension agents, certified crop advisors, crop consultants, environmentalists, agricultural policy makers. Written by Yuheng Qiu and Guodong Liu.https://edis.ifas.ufl.edu/hs1454
Homeowner Fact Sheet: Citrus Canker
Authors: Dewdney Megan M. , Zekri Mongi , Burrow Jamie D. , Roberts Pamela D.
Published: January 2023

Citrus cankers is a serious disease of all citrus cultivars and some citrus relatives, but is not harmful to humans and other animals. It is an introduced disease in Florida and is very economically damaging to the commercial industry. This disease is of concern to homeowners also, not only because of its economic effects on the  commercial industry, but because it is highly contagious and the majority of infected fruit on a severely affected tree may drop off the tree prematurely. This 4-page fact sheet is a minor revision written by M. M. Dewdney, M. Zekri, P. D. Roberts, and J. D. Burrow, and published by the Plant Pathology Department, May 2018.
PP194/PP116: Homeowner Fact Sheet: Citrus Canker (ufl.edu)
Rancang Bangun E-Commerce Produk Pertanian dan Perikanan Berbasis Android
Authors: Susandi Diki , Karyaningsih Dentik , Fajrin T. Revi Anshar , Hadi Irfan
Published: January 2023

Indonesia merupakan negara agraria yang sebagian besar penduduknya bekerja sebagai petani dan memiliki berbagai macam produk pertanian dan perikanan. Indonesia merupakan salah satu penghasil produk pertanian dan perikanan terbaik dan terbesar. Kabupaten Lebak khususnya merupakan wilayah yang mayoritas penduduknya adalah bertani dan budidaya perikanan. Meski hasil panen melimpah ruah, namun hal itu tidak  meningkatkan penghasilan dan kesejahteraan petani. Harga jual produk pertanian dan perikanan dinilai masih tidak sesuai dengan yang diharapkan, apalagi para petani masih belum bisa lepas dari jerat para pengepul yang membeli hasil panen dengan harga murah. Karena masalah pemasaran hasil pertanian yang tidak mempunyai akses keluar dengan biaya trasportasi yang cukup terbatas khususnya yang berada wilayah Kabupaten Lebak yang merupakan daerah tertinggal yang sulit dijangkau trasportasi sehingga biaya cukup mahal dalam menjual produk pertanian dan perikanan mereka, maka salah satu solusi dalam mengatasi masalah tersebut adalah dengan dibangunnya E-Commerce untuk memasarkan produk-produk hasil pertanian dan perikanan tersebut secara online agar mengurangai kendala-kendala pemasaran yang selama ini terjadi. Metode pengembangan aplikasi pada penelitian ini menggunakan metode prototype dan pengujian aplikasi menggunakan metode black box testing. Hasil penelitian ini adalah aplikasi E-Commerce produk pertanian dan perikanan berbasis android yang dapat digunakan dalam menjual dan membeli produk pertanian dan perikanan. Berdasarkan  pengujian sistem dengan black box testing  bahwa aplikasi E-Commerce Produk pertanian dan perikanan berbasis android 100% fungsional sistem berjalan dengan baik.
Il reddito di cittadinanza in italia: un caso di rivoluzione passiva
Authors: Ciccarelli Roberto
Published: January 2023

A tre anni dall'introduzione del "Reddito di Cittadinanza" in Italia, nel dibattito pubblico non è stato compresa a sufficienza la reale portata di una riforma che vincola, almeno sulla carta, il riconoscimento di un sussidio di ultima istanza a precisi e rigidi obblighi. In questo articolo si forniscono una serie di ipotesi per spiegare questo fenomeno che sarà interpreta- to sia in termini culturali che politici. Si utilizzerà una categoria ripresa da Antonio Gram- sci, quella di "rivoluzione passiva", adeguatamente contestualizzata e rielaborata. Si spie- gherà come il reddito di cittadinanza sia configurabile, per come è stato concepito e per come è stato gestito fino ad oggi, nella stessa cornice. In particolare, sarà evidenziato il doppio ruolo svolto da una simile misura: da un lato, essa si muove in una prospettiva di giustizia sociale, ma riconosce un sostegno condizionato nel tempo solo a una parte dei po- veri assoluti statisticamente rilevati in base a criteri meramente fiscali; dall'altro lato, evi- denzia l'esigenza di un controllo sociale vincolato a un'idea astratta di lavoro e distingue i poveri abili al lavoro da quelli non abili.