bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Learning Creativity in Early Childhood Through Learning Media Loose Part: Energetic, Concentrated and Creative
Authors: Sumarmi Sumarmi , Afendi Achmad Ruslan
Published: December 2022

Loose Part Media is an effective learning method that can increase children's creativity. This paper aims to test loose part media can increase learning creativity in early childhood. This study uses a qualitative approach with a descriptive method. Data collection methods used are observation, short interviews, and documentation. Sources of data obtained from children's play activities and children's work are documented directly as the main informant and explained using children's stories. The subjects of this study were early childhood, as much 15 people. Research data processing is carried out systematically so that the effectiveness of the data can be used to draw conclusions. The results of this study indicate that the application of loose-part media is proven to be effective in increasing the creativity of early childhood learning. This can be seen from the behavior shown by children in learning activities using loose part media, namely energetic, concentration, and creative. Loose-part media also encourages children to build knowledge around them through observing, asking questions, investigating, and solving their own problems, it will increase children's creativity when they play. Loose part media is media that is always used by teachers in the teaching and learning process in the classroom. This is due to its flexibility in every lesson, its ease in using in games, and is liked by children. In addition, this loose part of media also gives freedom for children to express their ideas, creativity, and imagination in activities through these media.
The Effect of Work Environment, Work Ethics, Work Culture, and Work Motivation on Performance of Environmental Services in Labuhanbatu Regency
Authors: Aini Nur , Nasution Ade Parlaungan , Siregar Nurintan Asyiah
Published: December 2022

Source power man is factor mover main from whole activity company . Type study this character quantitative , which becomes the place study this is Environmental Service Labuhanbatu district. In study this is what becomes population is employee Environmental Service Labuhanbatu as many as 30 people. Data collection is carried out with a spread questionnaire using google form and measured with a scale likert. Data analysis techniques in research this use PLS (partial least square) analysis which is analysis equality -based Structural Equation Modeling (SEM) variant with use softwear SmartPLS 3. Research results this show that environment work , ethics work , culture work and motivation work take effect significant to performance Environmental Service Labuhantu district.
L’adeguatezza dei modelli 231 in relazione alla safety nelle società del settore aviation alla luce della recente interpretazione dell’art. 2638 c.c.
Authors: Pilia Michele
Published: December 2022

L’attenzione alla sicurezza, connessa anche ai recenti sinistri relativi agli eventi del caso “Boeing 737 max”, il recente protocollo d’intesa raggiunto tra l’ENAC e la Scuola Superiore della Magistratura, finalizzato ad una maggiore consapevolezza reciproca per portare l’amministrazione della giustizia più vicina possibile alla realtà aviation in cui la stessa si troverà ad operare, e infine il crack Alitalia, hanno imposto un’ulteriore riflessione sulla natura dei problemi afferenti la safety degli aeromobili sia sotto il profilo tecnico (di progettazione, realizzazione o impiego), sia sotto il profilo normativo-giuridico. Questo ha condotto le società operanti nel settore a domandarsi se i loro modelli di raccolta delle segnalazioni e di comunicazione con l’ENAC dovessero essere ripensati, specie in considerazione dell’astratta configurabilità dell’art. 2638 c.c. e del conseguente illecito connesso con l’art. 25ter D.lgs. n. 231/2001.
 
Parole chiave: comunicazioni obbligatorie, enti di vigilanza, ENAC, art. 2638 c.c., safety, modello 231
 
The recent attention about the safety related to the aviation incident, expecially the "Boeing 737 max" case, the new memorandum of understanding reached between Ente Nazionale Aviazione Civile (“ENAC”) and the Italian Scuola Superiore della Magistratura aimed at greater mutual awareness to bring the justice’s administration as close as possible to the aviation reality, and eventually the Alitalia’s crack, require further reflection on the aircraft safety from a technical standpoint (design, construction or use) and legal point of view. This has led the aviation’s companies to a rethinking of their reporting policy and their interactions with ENAC, especially in view of the potential configurability of art. 2638 civil code and the consequent offense connected with art. 25ter D.lgs. n. 231/2001.
 
Keywords: mandatory communication, surveillance Authority, ENAC, art. 2638 c.c., safety, modello 231
About the reasons for the decrease in the spawning stock of black-backed herring in Volga River
Authors: Voynova T. V. , Barabanov V. V. , Chaplygin V. A.
Published: December 2022

The long-term data of the spawning stock of passing herring are analyzed in accordance with its commercial catches. The current state of the age structure of producers with a division into replenishment and remainder is considered. The main reasons for the decline in the spawning stock are identified and recommendations are given for commercial exploitation aimed at preserving and restoring the population of black-backed herring.
Distribution of spawning grounds of pacific herring Sakhalin-Hokkaidо and Decastri population off the west coast Sakhalin Island (Japan Sea)
Authors: Ivshina E. R.
Published: December 2022

The results of the spawning grounds distribution of the Pacific herring of the Sakhalin-Hokkaidо and Decastri populations off the west coast Sakhalin Island (Sea of Japan) for the period from 1930–1950 to 2020 are summarized. Including data on the distribution of spawning grounds, eggs density in 2019 and 2020. Available information indicates clear signs of a modern increase in the number of herring of the populations under consideration.
Beaked redfish Sebastes mentella of the Irminger Sea – current view on the stock structure, its status and management measures
Authors: Rolskii A. Y.
Published: December 2022

The paper aims at giving a brief review of the population structure, abundance and biomass dynamics of beaked redfish of the Irminger Sea obtained during the trawl acoustic surveys and analytical assessment. The adequacy of the current fisheries management measures for redfish in NEAFC is assessed. It was shown, that recent findings of the foreign genetic research apparently contradict to the relevant population structure for beaked redfish of the Irminger Sea applied in ICES, which specifies four stocks of the species. The ICES’ position of the depressed shallow pelagic and deep pelagic redfish stocks lacks substantial evidence from the results of the surveys in 2018–2021 and analytical assessment carried out by the Russian experts for the single redfish stock. The results allow assessing the current state of the stock as ‘good’. Thus, ICES/NEAFC recommendations that there shall be no directed fisheries neither for the shallow pelagic redfish stock nor the deep pelagic redfish stock in the Irminger Sea and adjacent waters until 2024 are insufficiently substantiated and need to be revised.
BUDDHA DARSANA AND A GLIMPSE OF TIBETAN MEDICINE
Authors: O Sruthi
Published: December 2022

Philosophy has a vast arena of application which embraces all branches of human knowledge.Buddha darsana is a non
vedic philosophy founded by Sree Goutama Buddha in the 5th century. According to Buddhists, the notion that things
exists when everything is void, is termed ignorance. They believe that correct knowledge will destroy ignorance and
thus will put an end to birth,aging and leads to ultimate liberation from all miseries.The essence of Tibetan medicine has
very profound roots in Buddhist philosophy.According to Tibetan medicine there are many specific causes of diseases,
but the basic cause is ignorance which leads to three mental poisons of desire,hatred and obscuration.These in turn give
rise to imbalance in three humors and results in disease of an individual. Ayurveda and Tibetan medicine shares
similarities in their basic concepts.
A STUDY ON CUSTOMER SATISFACTION TOWARDS E-BANKING SERVICES WITH SPECIAL REFERENCE TO AXIS BANK IN RAMANATHAPURAM TOWN
Authors: Khan S. Nazeer , Deepika B.
Published: December 2022

In traditional banking, the products and services handed by bank branches are not acceptable to meet the customer
needs and solicitation. Customers are the king in any business. Every business should know the customer perception
and satisfy their requirements.Customers are precipitously more demanding with precious services customized to their
exact requirements, at least bring and instantly done. It is possible by the use of Information technology in banking
sector.In Moment's script E-Banking service plays a vital part in attracting new customers and retaining old customers.
Without e-banking service no banks can survive in this competitive banking business.E-Banking means the provision of
information about a bank and its services through a home runner on the World Wide Web (WWW).E-Banking services
give customer access to accounts, the capability to transfer their plutocrat between different accounts, and making
payments or applying for loans through E- Channels. Electronic Banking is else called as Internet Banking or Virtual
Banking or Online Banking or Web Banking.E – Banking is the medium and rearmost delivery channel to be offered by
the retail banks.It handed number of benefits to customer in term of easy to use and at least cost of deals;it may be either
through internet, telephone or other electronic delivery channels. Nationalization was a structural change in the
performance of marketable banks which redounded in to the emergence of public sector banks. Privatization leads to
the emergence of private sector banks and globalization which eased the entry of foreign banks in India. This super
study helps to know the satisfaction position of customers towards e – banking services handed by Axis Bank in
Ramanathapuram Town.Then E – Banking services includes ATM service, POS using benefit card and credit services,
mobile banking and EFT etc.
RETROSPECTIVE STUDY OF THORACOTOMY IN PULMONARY TUBERCULOSIS PATIENTS IN
TERTIARY HEALTHCARE CENTRE OF SOUTH GUJARAT.
Authors: Chhabra Arjun , Kansal Sandeep , Chokshi Jay
Published: December 2022

Background: Pulmonary Tuberculosis is one of the most prevalent infections in India and contributes significantly to
morbidity and mortality.While most patients with TB can be successfully treated with anti-tuberculosis chemotherapy,
Thoracic surgery is an important adjuvant strategy for these patients especially the one with MDR/XDR. Aim: To
compare VATS and conventional open thoracotomy with decortication in pulmonary TB patient's requiring surgery.
Methodology: A Retrospective study was conducted on a sample size of 10 patients who presented with features of
pulmonary TB, mainly referred from TB OPD with chest X-ray/ HRCT thorax findings. Results: There was significant
association was found among Both methods and various variables like Duration of hospital stay, back to routine work
after surgical procedure and VAS score for pain assessment. Conclusion: This study suggests that VATS, a minimally
invasive procedure with its implied decreased perioperative morbidity and better functional outcome, should be
preferred over the traditional OT procedure whenever feasible to do so.
A Robust Region Control Approach for Simultaneous Trajectory Tracking and Compliant Physical Human-Robot Interaction
Authors: Li Xiangyun , LU QI , Chen Jiali , Jiang Ning , Li Kang
Published: December 2022

The robot manipulator is widely used in healthcare tasks owning to its advantages of the virus immunity, the intensive service capability, etc. For the safe and smooth robot-assisted healthcare task execution, real-time motion tracking controls and compliant physical human-robot interactions are concurrently important control objectives. In this work, the uncertainty and disturbance estimator (UDE)-based robust region tracking controller for a robot manipulator is developed. The regional feedback error is derived from the potential function to drive the robot manipulator end-effector converging into the target region, where the safe and compliant physical human-robot interaction can be achieved. Utilizing the back-stepping control approach, the regional feedback error is seamlessly integrated into the UDE-based control framework, where the UDE is employed to estimate and compensate unknown payloads, unmodeled dynamics and frictions. Due to the simple structure and strong robustness of the proposed method, only the minimum model information, i.e., a constant inertia matrix, is needed for implementation on multi-degrees of freedom robot manipulators without additional force/torque sensors. The Lyapunov method is used to analyze the stability of the closed-loop control system. With two 7 degrees of freedom(DoFs) redundant manipulators and one 6 DoFs nonredundant manipulator, experimental studies including 3D lemniscate trajectory tracking, human–robot interaction for bilateral rehabilitation and temperature measurement are carried out for controller effectiveness validation. Compared to benchmark adaptive region control method, the proposed approach achieves better robustness with 0.022 m less mean absolute errors and 0.022 m less root mean squared errors in the presence of model uncertainties.

This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible.
Distributed Impedance Control of Coordinated Dissimilar Upper-Limb Exoskeleton Arms
Authors: Tahamipour-Z. S. Mohammad , Mattila Jouni
Published: December 2022

Upper-limb exoskeleton (ULE) arms have the potential to assist humans in accomplishing tasks by distributing a heavy load. ULE arms are designed to be comfortable and lightweight wearable robotic devices, a design that has resulted in the complexity of their structures, actuators, and power transmissions. Additionally, different ULE vendor structures and biomechanical variations between humans have resulted in dissimilar coordinated ULE arm systems. These complex multiple ULE arm systems can be handled through adaptive virtual decomposition control (VDC) if unknown dynamic models are not considered. Accordingly, this paper proposes a new distributed framework for the adaptive impedance-based VDC method to address the abovementioned challenges and thereby enhance the performance and robustness of the ULE arm systems. To that end, the proposed control method has a prediction capability and an ancillary control law for coordinated dissimilar ULE arms holding a common object. The system stability is analyzed using the input-to-state stability approach. The performance of the proposed controller is evaluated both in simulation with six coordinated ULE arms and in an experiment with two commercial coordinated ULE arms each with seven degrees of freedom. Four scenarios are performed with different internal arm forces with and without an obstacle. The simulation and experiment results are compared with a state-of-the-art adaptive VDC method and show the superiority of the proposed control method.
Robust Cough Detection with Out-of-Distribution Detection
Authors: Chen Yuhan , Attri Pankaj , Barahona Jeffrey , L. Hernandez Michelle , Carpenter Delesha , Bozkurt Alper , Lobaton Edgar
Published: December 2022

Cough is an important defense mechanism of the respiratory system and is also a symptom of lung diseases, such as asthma. Acoustic cough detection collected by portable recording devices is a convenient way to track potential condition worsening for patients who have asthma. However, the data used in building current cough detection models are often clean, containing a limited set of sound categories, and thus perform poorly when they are exposed to a variety of real-world sounds which could be picked up by portable recording devices. The sounds that are not learned by the model are referred to as Out-of-Distribution (OOD) data. In this work, we propose two robust cough detection methods combined with an OOD detection module, that removes OOD data without sacrificing the cough detection performance of the original system. These methods include adding a learning confidence parameter and maximizing entropy loss. Our experiments show that 1) the OOD system can produce dependable In-Distribution (ID) and OOD results at a sampling rate above 750 Hz; 2) the OOD sample detection tends to perform better for larger audio window sizes; 3) the model’s overall accuracy and precision get better as the proportion of OOD samples increase in the acoustic signals; 4) a higher percentage of OOD data is needed to realize performance gains at lower sampling rates. The incorporation of OOD detection techniques improves cough detection performance by a significant margin and provides a valuable solution to real-world acoustic cough detection problems.
A Robust Approach for Hotspots Prevention and Resolution in Cloud Services
Authors: Wu Jiaxi , Yang Wenquan , Han Xinming , Qiu Yunzhe , Gudkov Andrei , Song Jie
Published: December 2022

Cloud providers offer virtual machines (VM) located in physical machines (PM) using the “pay-as-you-go” model to satisfy emerging demand for online computational services. If the instantaneous utilized capacity requested by VMs exceeds a certain threshold of the total capacity a PM can offer, a hotspot happens and may cause unacceptable VM performance degradation. Hotspots can be resolved by relocating some VMs to other PMs using live migration. However, the problem of selecting which VM(s) to release is challenging because the utilized capacity demanded by VMs changes continuously over time. In this work, we propose a Predicted Mixed Integer Linear Programming (MILP) Robust Solver (PMRS), which predicts the utilized capacity range of each VM and applies the Γ-robustness theory to ensure that PM is hotspot-safe with desired probability. The latter allows us to formulate the hotspot resolution as a Γ-robust knapsack problem (Γ-RKP) that can be solved by a novel MILP model. Extensive experiments based on real-trace data and large-scale synthetic data demonstrate the effectiveness of the PMRS. More encouragingly, the application of the PMRS in the real-production environment benefits Huawei Cloud by resolving all existing and 94%+ potential future hotspots with minimal migration overhead.Cloud providers offer virtual machines (VM) located in physical machines (PM) using the “pay-as-you-go” model to satisfy emerging demand for online computational services. If the instantaneous utilized capacity requested by VMs exceeds a certain threshold of the total capacity a PM can offer, a hotspot happens and may cause unacceptable VM performance degradation. Hotspots can be resolved by relocating some VMs to other PMs using live migration. However, the problem of selecting which VM(s) to release is challenging because the utilized capacity demanded by VMs changes continuously over time. In this work, we propose a Predicted Mixed Integer Linear Programming (MILP) Robust Solver (PMRS), which predicts the utilized capacity range of each VM and applies the Γ-robustness theory to ensure that PM is hotspot-safe with desired probability. The latter allows us to formulate the hotspot resolution as a Γ- robust knapsack problem (Γ-RKP) that can be solved by a novel MILP model. Extensive experiments based on real-trace data and large-scale synthetic data demonstrate the effectiveness of the PMRS. More encouragingly, the application of the PMRS in the real-production environment benefits Huawei Cloud by resolving all existing and 94%+ potential future hotspots with minimal migration overhead.
Improving Fast Ripples Recording with Model-Guided Design of Microelectrodes
Authors: Al Harrach Mariam , Dauly Gautier , Seyedeh-Mousavi Hajar , Dieuset Gabriel , Benquet P , Ismailova Esma , Wendling Fabrice
Published: December 2022

Objective: Microelectrodes allow for the recording of neural activities with a high spatial resolution. However, their small sizes result in their high impedance, therefore, leading to a high thermal noise and a poor signal- to-noise ratio. In the context of drug-resistant epilepsy, efficient Fast Ripples (FRs; 250-600 Hz) detection can help in pre-surgical investigations and delineation of epileptic zones. Consequently, good quality recordings with a high spatial resolution promise to improve the surgical outcome. This work aims at proposing a reliable model-based microelectrode design that is optimized for FRs recordings and detection.

Methods: A 3D microscale computational model simulates the FRs generated in the CA1 subfield of the hippocampus. It couples with the electrode-tissue interface characteristics that account for the microelectrode’s biophysical properties and their impact on the recorded signal. To validate this model, analyses of the electrode’s geometrical (diameter, position, and direction) and physical (materials, coating) characteristics were con- ducted in order to propose an optimal microelectrode de- sign tuned for FRs recording. In addition, 

Results: Experimental signals were recorded from mice in the hippocampal CA1 subfield from different electrodes for comparison. ( between stainless steel, gold and gold coated with poly(3,4-ethylene dioxythiophene) /Poly(styrene sulfonate) (PEDOT/PSS)).

Conclusion: Both in silico and in vivo quantified results show a clear improvement in FRs observability using PEDOT/PSS coated microelectrode. 
Pertuzumab in Combination with Trastuzumab and Docetaxel in the Neoadjuvant Treatment for HER2-Positive Breast Cancer
Authors: Vieira Cláudia , Borges Andreia , Pereira Filipa F. , Antunes Pedro , Redondo Patrícia , Antunes Luís , Lopes José M. , Gonçalves Francisco R. , Borges Marina , Bento Maria J.
Published: December 2022

Introduction

This study aims to assess safety and effectiveness of pertuzumab in combination with trastuzumab and docetaxel in the neoadjuvant treatment (NeoT) of HER2-positive breast cancer.

Methods

Two consecutive retrospective cohorts (n = 94, 2012–2015 and 2015–2017) of adult women with HER2-positive breast cancer, receiving NeoT at the breast clinic in Portugal (IPO-Porto), were followed. All patients had surgery and received trastuzumab as adjuvant therapy. The 2012–2015 cohort received doxorubicin, cyclophosphamide, docetaxel plus trastuzumab, whereas the 2015–2017 cohort was treated with the same protocol plus pertuzumab.

Results

The 2012–2015 cohort was older (median 53 years), with locally advanced tumors (48.1%), mostly hormone receptor positive (59.3%). The 2015–2017 cohort was younger (median 43 years) with 60% operable tumors. Pathologic complete response (pCR) improved in the second cohort, while maintaining a good safety profile and tolerability. Clinical staging (p = 0.001) and hormone receptor (p = 0.003) were significant predictors of pCR, but not treatment regimen (p = 0.304).

Conclusion

Further research with larger samples and longer follow-up is needed to understand the clinical differences. Clinical effectiveness of treatment should also be measured through overall and progression-free survival.
MOVIMENTOS SOCIAIS URBANOS E A TRAJETÓRIA DO URBANISMO
Authors: Bitoun Jan
Published: December 2022

Procuro recompor a trajetória do urbanismo nas suas relações nos últimos cinquenta anos com os movimentos sociais urbanos. Formula-se a hipótese de que, no contexto da cidade latino-americana, o principal desafio para esses movimentos sociais era de levar os urbanistas a encontrar soluções para um problema que não havia sido resolvido na Europa: o do habitat de segmentos sociais em situações precárias e sem vínculos fixos com o mercado de trabalho, apresentando então diferenças com a questão do habitat operário. A análise dessa trajetória no Recife, com base em documentos fundantes das intervenções urbanísticas demonstra que as conquistas políticas e jurídicas não foram acompanhadas por grandes inovações no campo das técnicas urbanísticas. Essas deram prioridade sucessivamente a um tratamento técnico – funcionalista e à concepção de grandes projetos urbanos orientados pela visão da competição interurbana. Tais orientações parecem ter dificultado a continuidade intergeracional das lutas urbanas características do início do período.
FORMAS ESPACIAIS E PAPÉIS URBANOS
Authors: Sposito Maria Encarnação Beltrão
Published: December 2022

A análise das relações entre formas espaciais e papéis urbanos é realizada neste artigo, a partir das relações e distinções entre a cidade e o urbano. São valorizadas as determinações contemporâneas do processo de urbanização que redefinem as formas de expansão territorial das cidades e os conteúdos e práticas socioespaciais atinentes ao urbano. As articulações e diferenças entre três pares de qualidades do processo de urbanização e das cidades são a base da análise: transição e transitório, extensão e intensidade, mobilidade e imobilidade.
REGIÕES RETICULARES
Authors: Limonad Ester
Published: December 2022

Este ensaio introduz a ideia de regiões reticulares não-euclidianas. E o faz movido pela intenção de avançar teórica e metodologicamente, em um nível mais geral, na compreensão da organização e da produção contemporânea do espaço social, e em um nível particular, para situar a questão urbana e as tendências recentes da urbanização no Brasil. Essa categoria aparece como essencial para a construção de uma economia política do espaço, bem como para contribuir para explicar os fundamentos da divisão espacial do trabalho e o funcionamento da economia do sistema capitalista, por permitir analisar as atuais continuidades espaço-temporais que ora se estabelecem, verticalmente alterando as relações de centralidade prevalecentes.
DINÂMICAS DO MERCADO IMOBILIÁRIO NA PRODUÇÃO DO ESPAÇO URBANO E DA NATUREZA EM SALVADOR E REGIÃO METROPOLITANA (BAHIA)
Authors: Henrique Wendel
Published: December 2022

Na cidade de Salvador ou em sua Região Metropolitana, bem como nos demais municípios ao longo do Litoral Norte da Bahia, áreas já ocupadas ou altamente transformadas, são apropriadas pelos agentes do mercado imobiliário, muitos com capital estrangeiro, produzindo loteamentos e condomínios residenciais horizontais e verticais. Esses empreendimentos são associados a uma ideia de natureza primitiva, a qual se torna sinônimo de qualidade de vida e transforma-se em valor econômico, aumentando os preços de apartamentos, casas e edifícios. Os remanescentes da Mata Atlântica, a vista, a localização, a infraestrutura e os serviços oferecidos atraem os investimentos do mercado imobiliário e provocam um forte adensamento, tanto das formas quanto das pessoas, nesses espaços específicos. A produção do espaço urbano e da natureza pelos agentes do mercado imobiliário se vincula, portanto, com a mercantilização acentuada e veloz da cidade, da natureza e do espaço urbano.
БАКТЕРИЦИДНЫЕ СВОЙСТВА СЛЮНЫ ЧЕЛОВЕКА
Authors: Садулаева Я.А. , Усаева Я.С. , Турлова Ф.С.
Published: December 2022

Слюна вырабатывается и секретируется слюнными железами, представляет собой жидкость, которая содержит воду, электролиты, слизь и ферменты. Защитная роль и преимущества, включая буферизацию, реминерализацию в здоровой слизистой оболочке полости рта, иммунную защиту, пищеварение, смазку, диагностическую цель и анализ протеома, выполняются слюной. Обсуждаются функции слюны в поддержании здоровья полости рта и основные факторы, вызывающие изменения в секреции слюны? и значение слюны в развитии кариеса и образовании бактериального налета, а также обсуждается ее роль и функции, органические и неорганические компоненты в слюне.
Sexual dysfunction with complex etiopathogenesis centered on vulvar cancer
Authors:   Medical Center for Obstetrics-Gynecology and Sexology, NIȚESCU Vasile , MARINESCU Bogdan ,   Clinical Hospital for Obstetrics-Gyne- cology ”Professor Doctor Panait Sîrbu”, Calea Giulești, Bucharest, Romania, NEDELCU Ioan ,   General Dermatology Medical Center, Dermatological Surgery, BEURAN Mircea , NIȚESCU Valentin ,   Department of Surgery of the ”Floreasca” Emergency University Hospital, BĂCANU Florin ,   Pitié-Salpêtrière” University Hospital, General, Visceral
Published: December 2022

Normal sexual activity is conditioned by the morphophysiology of the integrity of the genital organs and of the human brain, respectively by the absence of associated pathology. In the reported case, the 57-year-old female patient presented for a gynecological consultation, having very intense vulvar itching. Previously, the patient addressed the dermatology department, where she was diagnosed with ”vulvitis with significant edema and erythema” for which she underwent local treatment for 4 weeks. After dermatological therapy, the itching improved slightly, but persisted in association with the local stinging sensation. The vulvar itching became very intense, and the patient solicited a gynecological reexamination. It has to be noted that the patient believed, at that time, that the itching was due to psoriasis, a disease she had been suffering from since she was 10 years old.The emergency investigations establi- shed the existence of vulvar cancer, due to bilateral vulvar tumor. It should also be mentioned that the patient was undergoing therapy for the diagnosis of paranoid schizophrenia, for that of chronic peripheral venous insufficiency, respectively for manifest menopa- usal disorders. In this context, sexual intercourse has completely disappeared, due to complex sexual dysfuncti- on, so that the libido, the erection, the copulation and the orgasm no longer existed.
Changes in Microbiome during the gestation period
Authors:   Department of Physiology and Immunology, “Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania, COJOCARU Manole
Published: December 2022

When studying the role of the microbiota in pregnancy, it is crucial to consider the stage at which the essential interaction between the host and its microbes begins. The gut microbiota changes dramatically during pregnancy. The gut microbiota during pregnancy is influenced not only by internal cues, but also by environmental factors, primarily by diet. The maternal microbiome has emerged as an important factor in gestational health and outcome and is associated with risk of preterm birth and fetuses morbidity. Microbial me- tabolites, e.g. short-chain fatty acids affect gut-brain signaling and the immune response. Pregnancy is shown to alter the maternal gut microbiota. Recent studies have suggested that changes to the microbiota during pregnancy may influence these pregnancy-associated metabolic changes. The vaginal microbiome becomes dominated by Lactobacilli species during pregnancy. Bacterial infections during pregnancy can be caused by a single species of bacteria, by an imbalance in the microbiomes, or by gut dissemination of bacteria. In pregnancy dramatical changes of the maternal microbiota affects neonatal immune responses and maturation the design product. Clinically, abnormal changes in the vaginal microbiome have been associated with pre- term birth. It is, therefore, not surprising that there are also significant changes in the micro- biome during pregnancy when there is an excess of weight with metabolic and immunolo- gical changes occur. We believe that the microbial alterations observed during pregnancy are vital for a healthy pregnancy. In this review, I summarize the known changes in microbial composition througho- ut pregnancy in the gut, vagina, oral cavity and placenta.
Insights for COVID-19 in 2023
Authors: Martín-Sánchez Francisco Javier , Martínez-Sellés Manuel , Molero García José María , Moreno Guillén Santiago , Rodríguez-Artalejo Fernando , Ruiz-Galiana Julián , Cantón Rafael , De Lucas Ramos Pilar , García-Botella Alejandra , García-Lledó Alberto , Hernández-Sampelayo Teresa , Gómez-Pavón Javier , González del Castillo Juan , Martín-Delgado Mari Cruz , Bouza Emilio
Published: December 2022

Predictions for a near end of the pandemic by the World Health Organization should be interpreted with caution. Current evidence indicates that the efficacy of a fourth dose of classical mRNA vaccines (BT162b2 or mRNA-1273) is low and short-lived in preventing SARS-CoV-2 infection in its predominant variant (Omicron). However, its efficacy is high against severe symptomatic infection, hospitalization and death. The new vaccines being introduced are bivalent and active against the Omicron variants. Potential new vaccines to be introduced in the coming year include a vaccine based on a recombinant protein that emulates the receptor binding domain of the Spike protein under development by the Spanish company Hipra, as well as vaccines for nasal or oral administration. Available information suggests that vaccines against COVID-19 can be administered in association with influenza vaccination without particular complications. New drugs against COVID-19, both antiviral and anti-inflammatory, are under investigation, but this does not seem to be the case with monoclonal antibodies. The indication to use masks in some circumstances will be maintained next year in view of the accumulation of scientific data on their efficacy. Finally, the long COVID or Post-COVID syndrome may continue to affect a very high proportion of patients who have had the disease, requiring combined diagnostic and therapeutic resources.
Efektifitas Undang-Undang Nomer 16 Tahun 2019 Tentang Batas Usia Pernikahan
Authors: Halilurrahman M.
Published: December 2022

Paper ini menjelaskan tentang efektifitas Undang-Undang nomor 16 Tahun 2019 tentang pembatasan usia pernikahan di Pulau Bawean dan paper ini bertujuan untuk mengetahui secara mendalam apakah Undang-Undang nomor 16 Tahun 2019 tentang pembatasan usia pernikahan sudah diterapkan dan berjalan dengan efektif pada masyarakat pulau Bawean. Jenis penelitian yang digunakan adalah kualitatif dengan pendekatan yuridis empiris. Hasil penelitian menunjukkan bahw Undang-Undang nomor 16 Tahun 2019 tentang pembatasan usia pernikahan belum efektif pada masyarakat bawean karena masih banyaknya angka pernikahan di bawah umur yang dilakukan di kalangan masyarakat. Kedua, KUA Sangkapura telah mensosialisasi kepada masyarakat tetapi masih banyak faktor-faktor yang menghambat upaya KUA untuk menjalankan UU Nomor 16 Tahun 2019 secara efektif
Preferensi Masyarakat Pedesaan Terhadap Produk Keuangan Syariah
Authors: Suhairiyah Suhairiyah , Kunaifi Aang , Kadir Abdul
Published: December 2022

Industri keuangan syariah telah merambah wilayah pedesaan. Melalui perkembangan koperasi syariah yang sebelumnya dikenal dengan baitul maal wa at-tamwi (BMT) masyarakat pedesaan bisa menikmati layanan dan produk keuangan berbasis syariah. Artikel ini ditulis untuk mendeskripsikan bagaiamana preferensi masyarakat pedesaan terhadap produk keuangan syariah dan faktor-faktor apa saja yang menentukan kekuatan preferensi masyarakat terhadap produk keuangan syariah. Untuk mengeksplorasi dan mendeskripsikan hal tersebut penelitian disusun dengan pendekatan kualitatif melalui pengamatan terhadap realita aktivitas di beberapa BMT serta melalui wawancara mendalam terhadap masyarakat yang merupakan anggota BMT dan melakukan transaksi dengan BMT dalam beragam akad. Temuan dalam penelitian ini menunjukkan bahwa tingkat preferensi masyarakat pedesaan terhadap produk keuangan syariah masing sangat rendah yaitu hanya mencapai angka 30 persen. Adapun factor rendahnya preferensi tersebut mayoritas disebabkan oleh minimnya pengetahuan mereka terhadap industry keuangan syariah, sehingga muncul asumsi bahwa tidak ada perbedaan antara produk keuangan syariah dan produk keuangan konvensional. Berdasarkan temuan di atas, maka implikasi penelitian ini diharapkan berdampak pada lebih masifnya program literasi dan inklusi produk keuangan syariah oleh seluruh stake holder, baik perbankan, koperasi syariah, lembaga pendidikan, serta para akademisi.
Nusyuz Penyelesain Konflik Keluarga Dalam Hukum Islam (Teori Dan Praktinya Di Indonesia)
Authors: Jalil Abd
Published: December 2022

Ikatan perkawinan merupakan suatu tujuan yang sangat utama dalam Islam. Nikah dilaksanakan untuk selamanya agar suami istri bersama-sama dapat mewujudkan rumah tangga impian sebagai tempat berlindung, menikmati curahan kasih saying dan dapat memelihara anak-anaknya sehingga mereka tumbuh dengan baik.

Konflik keluarga datang kapan dan diamana saja, jika tidak selesaikan akan berakhir pada pencerain. Islam sebagai  agama sempurna memberikan pedoman cara menyelesaikan konflik keluarga secarah bijaksana. dengan menjunjung tinggi harat dan martabat perempuan dengan memberkan hak-haknya. Begitu juga dengan laki-laki berikan solusi tampa merendahkan dan mendiskriminalkan perempuan.
Peran Istri Dalam Meningkatkan Ekonomi Keluarga, Tinjauan Fiqh Munakahat (Studi Kasus Istri Pekerja Home Industry Ikan Pindang Di Desa Telukjatidawang)
Authors: Masruha Masruha , Barakah Ainun
Published: December 2022

Abstrak: Peran istri dalam rumah tangga ada dua yaitu, peran publik dan domestik. Dalam hal ini, istri juga dapat ikut serta dalam membantu peningkatan ekonomi keluarga, sehingga perlu untuk mengetahui mengenai peran istri dalam meningkatkan ekonomi keluarga menurut pandangan fiqih munakahat. Peran seorang istri dapat menjadi ibu rumah tangga, mitra kerja suami dan pengusaha maka dari itu seorang istri tidak harus memiliki peran domestik saja akan tetapi seorang istri juga memiliki peran publik. Hukum seorang istri bekerja yaitu boleh tetapi dengan syarat harus mengikuti syariat islam dan mendapat izin dari suami dan kewajiban seorang suami yaitu memberi nafkah kepada seorang istri meski istri mempunyai penghasilan sendiri. Metode penelitian yang digunakan dalam penelitian ini adalah metode kualitatif, sedangkan teknik pengumpulan data yang digunakan adalah observasi, interview mendalam dan dokumentasi. Teknik analisis data yang digunakan adalah reduksi data, penyajian data dan penarikan kesimpulan atau verifikasi. Pengecekan data menggunakan perpanjangan pengamatan, meningkatkan pengamatan dan trianggulasi.
Analisa Hukum Mediasi Sengketa Wakaf Dalam Putusan Perkara No. 474/Pdt.G/2020/PA.Gs Di Pengadilan Agama Gresik
Authors: Suprianto Agus
Published: December 2022

Menurut UU Wakaf, pergantian nadzir perseorangan dapat dilakukan dengan tiga cara yaitu pengunduran diri nazhir perseorangan, atas dasar inisiatif KUA, dan atas usulan wakif atau ahli waris wakif. Sengketa wakaf salah satunya persoalan penggantian nazhir. Kompetensi absolut untuk penyelesaian sengketa wakaf di Pengadilan Agama. Penelitian ini bertujuan untuk mengetahui apa isi putusan kesepakatan perdamaian sengketa wakaf dalam putusan Pengadilan Agama Gresik No. 474/Pdt.G/2020/PA.Gs. Jenis penelitian yang digunakan adalah penelitian hukum normatif-empiris dan bersifat deskriptif analitis. Hasil yang ditemukan dari penelitian ini adalah pertama, isi putusan kesepakatan perdamaian berbunyi : “menghukum Para Penggugat, Tergugat I dan Tergugat II untuk mentaati dan melaksanakan isi persetujuan yang telah disepakati tersebut.“ kedua, putusan akta kesepakatan perdamaian sengketa wakaf ini adalah bersifat mengakhiri sengketa diantara para pihak, kesepakatan perdamaian dengan memberi amanah musyawarah lanjutan, mengikat bagi para pihak dan pihak terkait, memiliki sifat dapat dilaksanakan atau eksekutorial, mediasi menjadi cara alternatif penyelesaian sengketa yang lebih cepat, mengandung rasa keadilan substantif, seperti dengan pergantian komposisi nadzir baru, mencerminkan perilaku iktikad baik para pihak dalam mediasi, mengedepankan proses perundingan, kesepakatan perdamaian dalam mediasi tidak bertentangan hukum, kesepakatan yang terdokumentasi dan ditandatangani, kesepakatan yang terkuatkan oleh pengadilan, menghindari dampak negatif konflik sosial dan keagamaan, memperbaiki / mempertahankan silaturahmi dan sesuai ketentuan al-Qur’an dan hadits.
Cement production and man: negative aspects of mutual influence
Authors: Chomaeva Madina
Published: December 2022

The factors of the main environmental pollutants that negatively affect human health are considered. Industry as a whole covers all stages of the resource cycle. The tendency to change the state of the environment can be observed under the influence of many factors, which will affect human health accordingly. Reasonable conclusions of aspects of mutual influence and interaction of industrial production and man are made.
On the issue of understanding the essence of patriotism in modern realities: a mechanism for combating external and internal enemies
Authors: Serednev Vladimir
Published: December 2022

The article analyzes the phenomenon of patriotism as one of the forms of nationalism. The author identifies two types of nationalism: conservative nationalism, the mechanism for achieving the goals of which is determined by legality within the legal field and the absolute sovereignty of the state, maintaining and strengthening its territorial integrity; radical nationalism aimed at achieving goals through direct violence or terror. The signs are revealed, in the presence of which patriotism is potentially transformed into chauvinism or xenophobia. The content of the policy of the West, which carries external and internal threats to the security and integrity of Russia, is noted. As a result of the analysis, the conclusion is formed that patriotism is a mechanism for protecting the state from an external enemy (it does not matter real or imaginary). Nationalism, on the other hand, realizes the possibility of counteracting the destruction of Russia by an internal enemy.
Analysis of the current situation in the domestic gold mining industry
Authors: Kradenykh Irina
Published: December 2022

The current activities of gold mining companies under economic sanctions are characterized. Such dynamic indicators as gold prices, production volumes by country and regions, and the number of operating companies have been determined and reviewed. The most vulnerable areas in the activities of enterprises and the possible prospects for further development of the industry are identified.
Response of Lowland Rice to Rice Crop Specific Npk Fertilizer at Badeggi Central Nigeria
Authors: Ibrahim, P. A. , Gbanguba, U. A. , Madukwe D
Published: December 2022

The trial was carried at National Cereals Research Institute Lowland Experimental field in the year 2019 and 2020 to evaluate the response of lowland rice to application of Rice Crop Specific NPK fertilizer 1and commercial NPK fertilizer which was applied at two levels each recommended blanket rate of 80:40:40 NPK/ha and higher rate of 120: 60:60 NPK/ha for lowland rice as well as the control (Zero fertilizer). The results indicated that application of fertilizer has significant effects on rice growth there by increased the height of rice at different weeks after fertilizer application compared to control. Rice straw and grain yield production was significantly affected with application and the rates. RCS fertilizer applied at 120:60:60/ha produced higher tonnage of rice straw and grain while application of RCS fertilizer at 80:40:40/ha produced similar rice straw and grain yield with application of NPK 15: 15:15: at rate of 120:60:60/ha. There the adoption of RCS-NPK formulation at rate 80:40:40 kg/ha is recommended against the higher rates from commercial NPK  to save cost for the resources poor farmer.
Profile of Women Who Undergo Tattoo in Basrah
Authors: Al hasan Hanaa
Published: December 2022

In modern times, the process of tattooing has withdrawn a lot of attention Investigators and consultants in the field of tattooing premeditated its significance regarding different perspectives such as sociological speculative grounds besides social factors effects on gender, one’s social identity, age group, sub-cultures regarding urban and ruler areas, occupational status. In this study, socio-cultural impacts and sociological implication perspectives of tattooing among young modern women in Basra were examined. The main purpose of this study is to find the root causes that influence young modern women to undergo tattoo embeddedness. Another purpose of this study is to find any social-cultural factors that are influencing or discouraging tattooing among young women and how these marks are helpful in communication as well as having a unique identity. This research was conducted in two parts reviewing literature review and conducting in-depth interviews. The inductive research approach was used for this purpose. The non-probability technique was used for sample selection which was five young college-going women. From the results, it was concluded that tattoos are becoming a powerful tool for individual self-expression and presentation of who they are. Inscribing tattoos on the body represents a person as a figurative symbol. Love, freedom, imagination, and idealism are a form of a few self-expressions that women like to represent through their inscribing bodies.
La calificación jurídica del vínculo plataforma - repartidores
Authors: Foddanu María Julia
Published: December 2022

Sumario:

I. Introducción. II. La calificación jurídica del vínculo plataforma-repartidores. Posturas. III. Los indicios de laboralidad de la OIT. IV. El accionar de la policía del trabajo y su convalidación judicial. V. Reflexiones Finales.
Условное деепричастие в лесном диалекте энецкого языка: корпусное исследование системы употреблений
Authors:   Institute of linguistic studies, RAS (St. Petersburg), Ovsyannikova Maria
Published: December 2022

This corpus-based study examines the functions of the conditional converb in Forest Enets and investigates the differences in its use between two generations of Enets speakers. In line with the previous descriptions, independent clauses with conditional converbs are used as self-addressed questions (yes/no, special, and alternative questions). The conditional converb of the verb ɛ ‘be’ when used with numerals is developing into a marker of approximation. Dependent clauses with conditional converbs include protases of conditional and concessive conditional constructions as well as complement clauses. This study discusses the diachronic relation between independent clauses with conditional converbs and the protasis of conditional constructions and concludes that either of the two directions of development is possible. Complement clauses with conditional converbs include, first, irrealis complements to negative propositional attitude predicates (dʲɔxara ‘not know’, dʲurta ‘forget’), which, showing signs of relatively recent grammaticalization, have hitherto received scant attention by scholars, and, second, sentential subjects in modal constructions with such predicates as sɔjza ‘good’, bɔɔ ‘bad’ etc. To compare the use of the Enets conditional converb across types of clauses and generations of speakers, this paper analyses the occurrence of the future tense marker on the converb, the order of clauses in multi-clause constructions, the range of verbs in the main and in the dependent clauses. Many of these parameters can be interpreted as the signs of the growing level of clause integration in the process of grammaticalization of polypredicative constructions.
Севернохантыйский как язык с чертами аккузативного и иерархического кодирования
Authors:   Institute of Linguistics, RAS (Moscow), Muravyev Nikita ,   University of Hamburg
Published: December 2022

This study features an alignment system in Kazym Khanty. Several facts including accusative marking of personal pronouns, verbal agreement with S/A and a strong tendency towards the clause-initial position of S/A suggest treating Kazym Khanty alignment as accusative. Meanwhile field and text data on the distribution of the active and passive voice as well as subject and subject-object agreement forms reveal several hierarchical coding effects. These include sensitivity of active/passive distinction to animacy and referentiality of the core participants and definiteness requirement of both participants for subject-object agreement. In sum, these facts suggest that Kazym Khanty can be considered an intermediate case of an alignment system combining certain surface properties of an accusative alignment with underlying hierarchical distribution patterns resembling some hierarchical coding systems of Algonquian and TibetoBurman languages.