bluuebunny/crossref_metadata_2025 huggingface dataset:
External and internal inputs affecting plasticity of dendrites and axons of the fly's neurons [Review]
Authors: Pyza* Elżbieta , Górska-Andrzejak Jolanta
Published: November 2023

Neurons and glial cells in the fly’s visual system exhibit circadian rhythms through changes in shape and size. Moreover, the number of synaptic contacts between these cells changes during the day and night and in the case of one type of synapses, feedback synapses, is maintained under constant conditions indicating an endogenous origin of this rhythm. The structural changes described above, involving the oscillations in the number of synapses and the size of interneurons and glial cells, are examples of plasticity in the central nervous system driven by internal inputs from a circadian clock and by external stimuli such as light. They are also modulated by visual and other sensory stimuli and by motor activity.
Noradrenaline-induced feeding responses in the rat do not depend on food characteristics
Authors: Swiergiel Artur , Wieczorek Marek
Published: November 2023

The noradrenergic system of the hypothalamic paraventricular nuclei (PVN) has been associated with feeding, but whether it controls feeding in a way that is relevant to energy balance is still unclear. Rats were maintained on a high energy, carbohydrate-rich diet (HC), or a low energy, carbohydrate-free, protein-rich diet (LP), until their daily energy intakes
equalized. When injected with noradrenaline (NA) into the PVN, they ingested the same amounts of both diets so that the animals on the LP diet consumed only half the total energy of those on the HC diet. Continuous delivery of NA into the PVN via a microdialysis probe induced chewing on non-nutritive pieces of corks. The same chewing pattern could again be elicited by the subsequent NA deliveries. It is concluded that the nutritional value of a diet is irrelevant to the NA feeding response. The failure of NA administration to increase rat feeding in terms of energy intake, combined with its ability to stimulate chewing, suggests that the primary role of the NA system of the PVN may not be controlling the carbohydrate and energy intake, but rather gating behavioral responses that under appropriate circumstances may lead to ingestion.
The auditory P3 from passive and active three-stimulus oddball paradigm
Authors: Wronka Eligiusz , Kaiser Jan , Coenen Anton
Published: November 2023

The aim of this study was the comparison of basic characteristics of the P3 subcomponents elicited in passive and active versions of the auditory oddball paradigm. A 3-stimulus oddball paradigm was employed in which subjects were presented with random sequence of tones while they performed a discrimination task in visual modality with no response to the tone (passive task) or responded to an infrequently occurring target stimulus inserted into sequence of frequent standard and rare non-target stimuli (active task). Results show that the magnitude of the frontal P3 response is determined by the relative perceptual distinctiveness among stimuli. The amplitude of frontal component is larger for the stimuli more deviated from
the standard in both passive and active tasks. In all cases however, a maximum over central or fronto-central scalp regions was demonstrated. Moreover, amplitude of this component was influenced by the strength of attentional focus – a significantly larger response was obtained in the active session than in its passive counterpart. The apparent parietal P3 responses
were obtained only in the active condition. The amplitude of this component is larger for the target than the non-target across all electrode sites, but both demonstrated a parietal maxima. This findings suggest that generation of early frontal P3 could be related to alerting activity of frontal cortex irrespective of stimulus context, while generation of later parietal P3 is related to temporo-parietal network activated when neuronal model of perceived stimulation and attentional trace are comparing.
Auditory perception of temporal order in centenarians in comparison with young and elderly subjects
Authors: Kolodziejczyk Iwona , Szelag Elzbieta
Published: November 2023

Temporal information processing controls many aspects of human mental activity and may be assessed by examining perception of temporal order in the tens of milliseconds time range. Although existing studies suggest an age-related decline in mental abilities, the data on the deterioration of temporal order perception seems inconsistent. Moreover, any evidence on
subjects aged over 70 years is lacking. The present experiment aimed to extend the existing data to extremely old people. Temporal order judgment (TOJ) for auditory stimuli was tested across the life span of approx. 80 years, i.e. in young (mean age 22 years), elderly (66 years) and very old (101 years) subjects. Age-related deterioration of performance was observed, with slight changes in elderly subjects and significant deterioration in centenarians which was more distinct in women than in men. The results confirm age-related decrease in temporal resolution which may be explained by slowing of information processing or of a hypothetical internal-timing mechanism. These effects may be influenced by different strategies used in particular age groups.
Treatment of lysosomal storage disorders: Focus on the neuronal ceroid-lipofuscinoses
Authors: Pierret Chris , Morrison Jason , Kirk Mark
Published: November 2023

Recent advances in our understanding of lysosomal storage disorders (LSDs) may lead to new therapies to treat the neuronal ceroid-lipofuscinoses (NCLs). In this review, enzyme replacement therapy, gene therapy, cell-mediated therapy and pharmaceutical treatments are considered across the LSDs and extended to therapies for the NCLs. It is likely that a combination of approaches will produce the most beneficial clinical outcome for treatment of pathologies displayed by the NCLs.
Effects of intra-hippocampal D-AP5 injections on one trial passive avoidance learning in adult laying hens (Gallus gallus domesticus)
Authors: Krause E. , Naguib Marc , Petow Stefanie
Published: November 2023

Domestic chickens are an established model organism for studies on learning and memory. Commonly, the chicks are used as subjects in several different learning tests, including one trial learning tests. However, for adult laying hens no such one trial learning tests have been established. In particular, there is no test established which focuses on the role of the hippocampus, a brain region, which is often critically involved in learning and memory consolidation. In this study we investigated the inhibitory effects of intra-hippocampal D-AP5 injections on a specific one trial passive avoidance learning test in adult laying hens (Gallus gallus domesticus). We used a step down avoidance learning paradigm (SDA) which is frequently used in rodents. Intra-hippocampal injections of D-AP5 impaired the learning abilities of adult laying hens compared to sham-injected control subjects. Thus, the experiments revealed that the hippocampus is critically involved in learning the inhibitory SDA task. Our results further indicate that the step down avoidance paradigm is suitable to examine learning and memory processes in adult laying hens.
The modified Color Density Spectral Array - an alternative method for sleep presentation
Authors: Pracki Tadeusz , Pracka Daria , Ziółkowska-Kochan Marzena , Tafll-Klawe Małgorzata , Szota Anna , Wiłkość Monika
Published: November 2023

The modified Color Density Spectral Array (CDSA) method used for graphical representation of sleep patterns is described in this article. CDSA was presented for the first time in 1987 by M. Salinsky and coauthors. This method was adapted to display frequency course and voltage of EEG signal during sleep. The overnight sleep records of 35 healthy volunteers of both sexes (23 women, 12 men; aged 19–26) were analyzed in order to verify the modification of CDSA method. We propose to use combining the hypnogram and CDSA method significantly increases the informative value of data and results in enhanced quality of sleep analysis.
Telencephalon ablation impairs goldfish allocentric spatial learning in a "hole-board" task
Authors: Durán Emilio , Ocaña Francisco , Gómez Antonia , Jiménez-Moya Fernando , Broglio Cristina , Rodríguez Fernando , Salas Cosme
Published: November 2023

The present work analyzes the involvement of telencephalon of goldfish in spatial strategies, using a procedure analogue to the hole-board task. With this aim, goldfish with sham operation or telencephalon ablation were trained to find a baited feeder within a twenty-five feeder matrix, which maintained stable spatial relationships relative to five peripheral landmarks. After training, different types of probe tests were conducted. Although both groups learned the task, probe trials showed that whereas the sham animals used the whole configuration of cues to implement map-like strategies the telencephalic animals used a guidance strategy based on cues located in the vicinity of the baited feeder. These results confirm the role of teleost fish telencephalon in the use of allocentric strategies obtained with other spatial procedures, and indicate that the hole-board task described here for goldfish is a useful tool to assess the neural bases of spatial cognition in teleost fish.
Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain
Authors: Gornicka-Pawlak Elzbieta , Jablonska Anna , Chylinski Andrzej , Domańska-Janik Krystyna
Published: November 2023

The present study investigated influence of housing conditions on motor functions recovery and exploratory behavior following ouabain focal brain lesion in the rat. During 30 days post-surgery period rats were housed individually in standard cages (IS) or in groups in enriched environment (EE) and behaviorally tested. The EE lesioned rats showed enhanced recovery from motor impairments in walking beam task, comparing with IS animals. Contrarily, in the open field IS rats (both lesioned and control) traveled a longer distance, showed less habituation and spent less time resting at the home base than the EE animals. Unlike the EE lesioned animals, the lesioned IS rats, presented a tendency to hyperactivity in postinjury period. Turning tendency was significantly affected by unilateral brain lesion only in the EE rats. We can conclude that housing conditions distinctly affected the rat’s behavior in classical laboratory tests.
Spinal cord hydrolysate ameliorate immunological reaction in experimental allergic encephalomyelitis
Authors: Kwiatkowska-Patzer Barbara , Michalkiewicz Jacek , Kubiszewska Izabela , Zielińska Joanna , Kasarello Kaja , Kurzepa Katarzyna , Lipkowski Andrzej
Published: November 2023

The aim of this study was to use the hydrolysate of pig spinal cord proteins to induce oral tolerance in the animal model of sclerosis multiplex - experimental allergic encephalomyelitis. The female Lewis rats were fed with hydrolysate of pig spinal cord proteins in two doses for one week before immunization, which was induced by injection of guinea pig spinal cord homogenate. At the peak of clinical symptoms (the 13th day post immunization) the rats were sacrificed and the spleen removed. Splenocytes were suspended in a culture medium and placed in microculture plates. The cells were stimulated with homogenate. The cells were cultured for seven days. Proliferation of splenocytes was estimated by means of methyl-3H thymidine incorporation. In supernatants of cultures of splenocytes the level of cytokines INF-gamma, IL-10, IL-4, and TGF-gamma was measured. It was demonstrated that homogenate-induced splenocytes of hydrolysate-fed rats gave rise to low proliferation as compared to the controls used. The IFN-gamma was inhibited in hydrolysate-fed animals. The hydrolysate of pig spinal cord proteins has a modulatory effect on the immune reaction, particularly on the orally-induced antigen-specific modulation of autoimmune response.
Electrical hippocampal activity during danger and safety signals in classical conditioning in the rat
Authors: Kasicki Stefan , Jeleń Piotr , Olszewski Maciej , Sławińska Urszula
Published: November 2023

The effect of stimuli predicting danger (DS) and safety (SS) in Pavlovian aversive conditioning on hippocampal local field potentials (LFP) was studied in 25 partially restrained adult male rats (Long-Evans). DS lasting 5 s preceded tail-shock, while SS overlapping DS during DS last 3 s predicted omission of shock. The power spectra of LFPs during trials were analyzed in theta and delta frequency bands. In DS, theta frequency during the last 3 s was lower that in first 2 s. In danger and safety situation theta peak frequency was different for dorsal CA1 activity (5.99 Hz vs. 6.86 Hz, respectively), while delta peak frequency was different for ventral CA1 (1.56 Hz vs. 1.07 Hz) for the last 3 s of trial. Differences in theta frequency in danger and safety situation may reflect differences in sensory processing during induced emotional states and/or related differences in motor behavior.
The effect of alpha-tocopherol in the acute ethanol intake and its withdrawal on penicillin-induced epilepsy
Authors: Kozan Ramazan , Ayyildiz Mustafa , Yildirim Mehmet , Agar Erdal
Published: November 2023

The present study was designed to investigate the influence of acute ethanol intake and its withdrawal on the anticonvulsant effect of alpha-tocopherol in penicillin-induced epileptiform activity. Ethanol-treated rats received a daily dose of 3 g/kg or 9.0 g/kg of 30% ethanol solution for 3 days. Thirty minutes after penicillin injection (500 units, i.c.), the most effective dose of alpha-tocopherol (500 mg/kg) was administered intramuscularly (i.m.). Acute administration of ethanol, in a dose of 3 g/kg, did not change either frequency or amplitude of penicillin-induced epileptiform activity, while dose of 9 g/kg ethanol significantly decreased the mean frequency of penicillin-induced epileptiform ECoG activity in the ethanol-treated group. Ethanol (9 g/kg) withdrawal also caused an increase in the amplitude of epileptiform ECoG activity in the withdrawal group. The results suggest that acute administration of high dose ethanol (9 g/kg) and alpha-tocopherol have some limited anticonvulsive effects in penicillin-induced epileptiform activity in rats.
Regional differences in the vulnerability of substantia nigra dopaminergic neurons in weaver mice
Authors: Martí Joaquin , Santa-Cruz Maria , Molina Vanessa , Serra Roger , Bayer Shirley , Ghetti Bernardino , Hervas Jose
Published: November 2023

Vulnerability of midbrain dopaminergic (DA) neurons in the weaver mouse was studied at postnatal (P) days 8 and 90, in chosen coronal levels throughout the anteroposterior (AP) extent of the substantia nigra pars compacta (SNc). Wild-type (+/+) and homozygous weaver (wv/wv) mice used were the offspring of pregnant dams injected in several cases with tritiated thymidine on embryonic days 11-15. DA neurons were identified for their tyrosine hydroxylase immunoreactivity. Data reveal that at P8, the frequency of both +/+ and wv/wv late-generated DA cells increases from rostral to caudal SNc. No apparent DA-cell loss was observed at P8 in the mutant genotype, irrespective of the AP level considered. However, throughout the AP, there was a significant reduction in the number of these neurons at any level in 90-day-old weavers. Comparison of P8 and P90 +/+ SNc suggests that cell death is not a major aspect in the developmental regulation of normal DA neurons, although numerical cell depletion in the postnatal development of weaver SNc probably results from the amplification of a basal cell-death process, which affected all the coronal levels studied.
Behavioral sleep in captive owl monkey (Aotus azarae) and squirrel monkey (Saimiri boliviensis)
Authors: Kantha Sachi , Suzuki* Juri , Hirai Yuriko , Hirai Hirohisa
Published: November 2023

The objective of this study was to test the hypothesis that activity-behavioral sleep parameters differ between nocturnallyactive owl monkeys and diurnally-active squirrel monkeys which are sympatric and of Bolivian origin. The total sleep time (TST) and sleep episode length (SEL) of 7 adult owl monkey siblings and 4 adult squirrel monkeys were quantitated by actigraphy for 7 days under captive conditions. The higher TST/24 h values and longer SEL/12 h quiescent phase quantitated for owl monkeys in comparison to that of squirrel monkeys clearly indicate that the behavioral sleep is markedly different between these two groups, though they are sympatric in wild. Significant differences noted in the sleep architecture between squirrel monkeys and owl monkeys can be attributed to the influences in the selected sleep niche, threat perception from predators, and disturbances from natural elements (especially rain) in the natural habitat.
IMPLEMENTASI MODEL PEMBELAJARAN APTITUDE TREATMENT INTERACTION DALAM MENINGKATKAN KEGIATAN BELAJAR DAN PRESTASI BELAJAR SISWA
Authors: Nursalim Eko , Mubarok Ramdanil
Published: November 2023

This studys' purpose was to analyze the application of the ATI learning model in improving learning activities and student learning outcomes in Al-Qur'an Hadith subjects. The method used in this research is classroom action research. As the result of the application of the ATI learning model can improve the learning activities of Madrasah Aliyah Nurul Hikmah Sangatta students. Thus could be proven by an increase in the percentage of student learning activities in cycle one by 78%. In the same in the next cycle, there was an increase of 88%. Furthermore, the implementation of the ATI learning model can also improve student achievement in the Qur'an Hadith subjects at Madrasah Aliyah Nurul Hikmah Sangatta where student learning completeness has an increase in the percentage in the first cycle of 82.5, as well as in the next cycle, there is an increase of 98%
INOVASI DALAM MANAJEMEN KURIKULUM: PEMANFATAN TEKNOLOGI DALAM MENINGKATKAN PEMBELAJARAN
Authors: Salimodo Devi , Christofer S. Taruna , Lestari Agus
Published: November 2023

This research aims to analyze the concept of educational technology, the function of ICT in learning, technology-based learning models, and barriers to its implementation. The method used in this research is the library research method. The research results show that educational technology is the application of science to learning to achieve effectiveness and efficiency. Innovative learning using educational technology can help build student character, develop scientific thinking skills, and increase student literacy. Technology-based learning models for instant project-based learning (PjBL), flipped classrooms, and self-organized learning environments (SOLE). Obstacles to its implementation are physical and non-physical obstacles. It is hoped this research will be able to provide a clearer view regarding the use of technology in improving the quality of learning and can assist in decision-making and continuous improvement in the education system.
PEMBERIAN INSENTIF DALAM MENINGKATKAN MOTIVASI DAN KINERJA GURU PAI SMP DI SANGATTA UTARA
Authors: Norjannah Siti , Afandi Nur Kholik
Published: November 2023

This research aims to explore the motivation and performance of PAI teachers, the role of providing incentives in increasing the motivation and performance of PAI teachers, as well as the supporting and in hibiting factors for increasing the motivation and performance of PAI junior high school teachers in North Sangatta. The method used is a descriptive qualitative research method. The result is that more motivated teachers tend to perform better at carrying out teaching tasks. The role of providing incentives in increasing the motivation and performance of PAI teachers includes a) as a driver of PAI teacher motivation, b) improving the quality of teaching, c) providing support for performance improvement; and d) increasing the quality of Islamic teaching. Meanwhile, in supporting factors for increasing the motivation and performance of PAI teachers include support from school principals and school administration staff; PAI teachers who have access to training and professional development; awards and recognition for teacher achievements; and good relationships between PAI teachers, fellow teachers, and parents of students. Meanwhile, the inhibiting factors are excessive workload, regarding incentives and a lack of resources.
Upaya Pencegahan Stunting Di Kelurahan Pasar Kliwon
Authors: Wijayanti Kenfitria Diah , Risyad Afdharu , Fitriasiwi Ade Hamrat , Almaas Ainanur Fauziyah , Hidayati Eka Nur , Rahma Maysti Aulia , Supriani Yuniati , Ramadhani Azizah Rahmah Putri , Pangrokti Ade Nining , Maharani Kinanthi , Annisyah Nurul
Published: November 2023

Stunting cases still often occur in the city of Surakarta, so the 'Sigrak Centingan' program was formed as an effort to reduce stunting. The program is running well, as evidenced by the data obtained there has been a decrease in the absence of stunting cases, especially in Pasar Kliwon Village. Based on this, the service carried out by Devotion  01 team aims to increase awareness of stunting and its prevention. Factors causing stunting in the Pasar Kliwon area are nutritional intake and low awareness of PHBS (Clean and Healthy Living Behavior). Devotion 01 team collaborates with posyandu cadres, PKK, residents, and local government through various work programs that can be carried out, including stunting socialization, posyandu, distribution of blood-added tablets, PHBS (Clean and Healthy Living Behavior), planting vegetable seeds, healthy Sunday, and waste reduction through eco-bricks. The results of the implementation of the work program indicate that the residents of Pasar Kliwon Village, especially young women, prospective brides, pregnant women, childbirth mothers, and breastfeeding mothers better understand the dangers of stunting and stunting prevention efforts can be carried out independently as early as possible.
Pengadaan Mini Garden “Mandaka Laksmi” di RW 13 Nusukan, Banjarsari, Surakarta dalam Rangka Program Kampung Iklim (Proklim)
Authors: Zuhro Nurul Shofiatin , Nita Elen , Fimala Aprilia , Anggreani Cindy Nur , Putri Azizah Amalia , Ayu Kusumaningrum Dennisa , Fikriana Nisa Inda , Puji Rahayu Fakih , Alam Ridwan Nur , Marshela Sylvia Anggi , Larasati Rima Fatima
Published: November 2023

The Climate Village Program (ProKlim) is a national scale program in order to encourage the community and all parties to take concrete actions to improve resistance to the negative impacts of climate change. In the village of Nusukan in particular RW 13 will be promoted by the Climate Village Program (ProKlim). To support the program, the procurement of a mini garden is carried out as an effort to move society and all parties in the face of climate change. The impact of this activity is to increase public knowledge and understanding of change climate and its impacts, as a real adaptation effort so that it can improve the degree of public health in the face of climate change, environment of RW 13 Nusukan, and can reduce GHG (Greenhouse Gas) emissions.
Workshop and Assistance on the Utilization of E-Learning at the Universitas Muhammadiyah Buton
Authors: Iksan Muhamad , Alzarliani Wa Ode , Samritin Samritin , Azaluddin Azaluddin , Awaluddin Muhammad
Published: November 2023

Improving the learning system chosen by the Universitas Muhammadiyah Buton (UM Buton) in order to compete in the era of disruption with advances in information and communication technology (ICT), particularly electronic-based learning systems, one of which is known as the e-learning learning system. Several professors at UM Buton had difficulties in adding learning material in the form of text, and video, visualizing quiz results and semester examinations, and building forums for question-and-answer sessions while utilizing e-learning. Based on these issues, the service team developed training and mentoring for UM Buton lecturers. It is hoped that with this training, UM Buton will be able to produce quality lecturers and highly educated skilled professionals who can keep up with the times and ICT-based technology while carrying out Catur Dharma tasks and responsibilities as a lecturer at Muhammadiyah Higher Education.
Peran Digital Marketing Dalam Upaya Pengembangan UMKM “Jajan Burger” Di Kota Surakarta
Authors: Intan KP Noviana , Suprayitno Suprayitno , Yoppi Syahrial
Published: November 2023

Technological developments make digital marketing superior for increasing the sales of a business. The "Jajan Burger" business tries to take advantage of this opportunity to expand its market share. The purpose of this article is to find out how to implement or apply Gojek digital marketing applications to small and medium businesses "Jajan Burger". The method used is in the form of preparation before starting a business, implementing digital marketing, and evaluating. The result of this research is that digital marketing can make sales prospects for "Jajan Burger" increase and be better known by many people.
Peningkatan Mutu dan Kualitas UMKM Dengan Membangun Brand dan Brand Exposure Untuk Memperluas Segmentasi Pasar
Authors: Fauzan Fahrul Alvin , Lestari Erma Puji , Ardio Karisma , Widaningrum Ida
Published: November 2023

This paper aims to describe the improvement in the quality and quality of MSMEs in Manuk village, Siman sub-district, Ponorogo district by building a brand and brand exposure to MSME products in the village so that the products can be better known so that the market segmentation reached becomes wider, so that it is expected to increase sales value and product sales. This activity is one of the work programs carried out by the group in the University of Muhammadiyah Ponorogo KKN program as a form of community service where it is hoped that this activity will have an impact on the Manuk village community, especially the MSME sector in the village can develop so that community welfare also increases. The program being carried out is in the form of designing a logo and making stickers as the identity of MSME products and making attractive packaging so that the product is more attractive to consumers.
Pentingnya Memiliki Jiwa Wirausaha Dalam Pengelolaan Produk Pertanian di Era VUCA (Volatility, Uncertainty, Complexity, Ambiguity) Pasca Era Pandemi Covid 19, Bagi Kelompok Wanita Tani Kel. Joglo, Kec. Banjarsari, Kota Surakarta
Authors: Suprayitno Suprayitno , Susanti Rina , Larasati Nike
Published: November 2023

This extension activity was conducted for anggota Kelompok Wanita Tani, Kel. Joglo, Kec. Banjarsari, Kota Surakarta.. The outcomes of this activity are: cheap participants' knowledge of the concept of entrepreneurship so that they have the right knowledge; benefit participants' insights on how to start a business and choose the right type of business; benefit participants' insights about possible business failures and ways to enter and resolve business failures.This activity is carried out with the following stages: Selection of participants to the community service, namely the board and members of Kelompok Wanita Tani; Submission of lecture materials, with a view to fostering an entrepreneurial spirit; Implementation of evaluation Evaluation is done by: before counseling conducted a question-answer to know each participant's initial knowledge about entrepreneurship special techniques or how to start a business. After the counseling finished the question and answer again about the same material. By comparing the results of answers that have been done, it will be known whether there is an increase in knowledge about the entrepreneurship and scope.
Pembinaan kepada Majelis Jemaat di Gereja Kristen Sulawesi Tengah (GKST) Anugerah Lena mengenai Panggilan Pelayanan
Authors: Tiladuru Vena Melinda , Sihombing Aeron Frior , Tampubolon Yohanes Hasiholan , Prianto Robi
Published: November 2023

The calling of service is an important concept in the context of church life. Within the church, each member is given a calling to serve according to the gifts bestowed upon them by God. It is crucial for the church to understand, strengthen, and facilitate the understanding of this calling for every individual within the congregation. The GKST Anugerah Lena congregation, as part of the Christian church community, is committed to encouraging and nurturing its members in understanding and developing their calling to service. In this regard, the community engagement team's journal activities (PKM) focus on the development of the calling to service within the GKST Anugerah Lena congregation. These PKM activities serve as a means to strengthen and solidify the calling to service for the members of the Majelis in GKST Anugerah Lena. This can help individuals within the congregation to have a clearer understanding of their personal calling within the church context and encourage them to live in accordance with that calling.
Penerapan Teknologi Mesin Pencacah Rumput Untuk Kemandirian Pakan Di Kelompok Ternak Ngudi Makmur
Authors: Badrawada I Gusti Gde , Yudha Venditias
Published: November 2023

Most of the livelihoods of residents in Klegen Hamlet, Trimulyo, Sleman District are mostly cattle breeders. Feeding with fresh grass needs to pay attention to the dimensions of the grass so that it is easily digested by livestock. This service activity focuses on the application of appropriate technology in the form of a grass chopper that is applied to the Makmur cattle group. The method of implementing the program is by dissemination and counseling on the operation and maintenance of machines. The grass chopper has a simple design that makes it easy to operate and maintain. The application of a grass chopper in the prosperous Ngudi livestock group can increase productivity in chopping grass by up to 30 times compared to the manual chopping process.
Penguatan Kapasitas Keorganisasian pada Ikatan Remaja Masjid Al-Mukminin Kelurahan Binawidya Kota Pekanbaru
Authors: Jaya Rony , Wahyudi Rodi , Rafi Mhd. , Muslim Muslim
Published: November 2023

The realization of faithful, pious, and noble youth is part of the youth development goals in Law 40 of 2009 concerning youth. The Mosque Youth Association (IRMA) Al-Mukminin, Bina Widya Village, Pekanbaru City can become a pioneer and a local scale spectrum to optimize the role of youth through activities to prosper the mosque as part of an effort to realize these youth development goals. Moving on from this, community service to increase the organizational capacity of IRMA Al-Mukminin was carried out. The purpose of the activity is to strengthen the understanding and organizational capacity of IRMA Al-Mukminin. The service method uses a transformative approach through the stages to know, identify problems, develop plans, take action, and build awareness in a sustainable manner. The results of community service activities were in the form of an increase in the organizational capacity of the Al-Mukminin Mosque Youth Association (IRMA) in Binawidya Village, Pekanbaru City.
Penerapan Copywriting Untuk Optimalisasi Digital Marketing Bagi Guru SMK Kridawisata Bandar Lampung
Authors: Permatasari Berlintina , Jaelani Jaelani , Suprayogi Suprayogi , Camelia Camelia
Published: November 2023

One of the successful points of digital marketers is their ability to maximize product and service promotion techniques using digital distribution channels such as websites, ad words, email, and various other social networks. Tourism vocational high school graduates are expected to be successful in the business world where they must be equipped with good marketing skills. Considering the importance of a marketer having copywriting skills, copywriting training is needed for them. The method used is the ABCD approach where the asset in this community is the SMK Kridawisata Bandar Lampung students who have started entrepreneurship. This activity was carried out directly in the form of basic marketing theory and ad copywriting training for the teacher of the school so that they can introduce digital marketing to their students. This training activity was carried out at SMK Kridawisata Bandar Lampung. The results of the activity show that there has been an increase in language and copywriting skills from each participant, where the most mastered skill on average is writing AIDA.
Psikoedukasi Pada Siswa SMPN 2 Dewantara Untuk Meningkatkan Motivasi Belajar Siswa
Authors: Safarina Nur Afni , Astuti Widi , Amalia Ika , Munizar Munizar , Mullah Ikram
Published: November 2023

Learning motivation is a driving force that comes from outside and within the individual to foster enthusiasm in terms of learning. Motivation is very important for students which is used to foster student enthusiasm for learning, which can increase student learning motivation. Students in their learning process need encouragement to direct their learning behavior to achieve the desired achievement. Motivation encourages students to be able to learn to achieve their learning goals and objectives so that students are able to generate motion or move themselves to do something in order to increase learning motivation. This service aims to provide psychoeducation to 30 students of SMPN 2 Dewantara. The results of this dedication show that psychoeducation is beneficial to the participants, of the 30 students who were given pretest questions, the results obtained were an average of 57.66 from these students, which from these results it can be concluded that psychoeducation has an impact on students regarding student learning motivation, students also understand the problem of learning motivation, efforts to increase learning motivation, and the role of motivation in learning.
Peran Mahasiswa KKN-T Dalam Pengembangan Embung Sari Agung Sebagai Destinasi Wisata Edukasi di Desa Ringinagung, Kec. Magetan, Kab. Magetan
Authors: Ningrum Dewi Retno , Andanto Ramadian Adistya , Sari Anisa Novita , Komalasari Belinda , Laily Devinda Annisa , Rahmatullah Hasan Ravi , Afifah Hasna Rifky , Pramudita Desma Asty , Solichin Solichin
Published: November 2023

Tourism has become an important milestone in economic development and provides positive impacts, including job creation, increased income and tax contributions. Educational tourism is a program where tourists visit tourist locations to gain direct learning experience. This program combines tourism elements with educational content, creating quality and meaningful activities. Educational tourism is concerned with new learning, cultural knowledge, and application of skills. The popularity of educational tourism continues to grow, for example in foreign language learning. Desa Ringinagung is an example of a tourist destination that has potential in the form of reservoirs and cultural richness. However, the potential of the reservoir has not been optimized as a tourist destination due to the lack of land planning and facilities. The planning process for educational tourism destinations in Embung Sari Agung aims to increase attractiveness, economic value and tourism focus. In this way, the Embung Sari Agung can develop as a tourist attraction that focuses on learning and meaningful experiences.
Peningkatan Keterampilan Teknologi Guru TK Melalui Pelatihan Microsoft Word
Authors: Sidiq Muhammad Fajar , Zulherman Dodi , Adam Ipam Fuaddina , Yuniati Trihastuti , Arifa Amalia Beladinna
Published: November 2023

This community service initiative is designed with the primary aim of providing training in the use of Microsoft Word to Kindergarten (TK) teachers in an effort to enhance their technological skills. The workshop aims to offer support to TK teachers in developing their competence in operating this word-processing software, which plays a crucial role in the modern education landscape. The background of this community service initiative reflects the educational transformation that has taken place in recent years. In this digital era, information technology and communication play an increasingly significant role in the learning process. Therefore, TK teachers need to have a strong understanding of relevant digital tools, with Microsoft Word being one of them. This workshop serves as a platform for TK teachers to comprehend and master various features and functions of Microsoft Word, ranging from basic to advanced levels. The importance of this workshop is also reflected in its potential positive impact. With TK teachers becoming more proficient in using Microsoft Word, they will be able to create more engaging, interactive, and relevant learning materials for children in today's digital age. This will enhance the learning experiences of TK students and provide a stronger foundation for their digital literacy development in the future. Furthermore, the workshop creates opportunities for TK teachers to share knowledge and experiences, strengthening collaborative networks among them. By sharing best practices in the use of Microsoft Word, they can support each other in their efforts to improve the quality of early childhood education. The workshop is expected to result in a significant improvement in the technological skills of TK teachers and, in turn, enrich the learning experiences of their students.
Desempenho de um sistema de irrigação por microaspersão no perímetro irrigado de Poção da Ribeira em Itabaiana/SE
Authors: Farrapeira Rafael de Oliveira , Faccioli Gregório Guirado , De Sousa Inajá Francisco
Published: November 2023

A água é um dos recursos naturais indispensáveis à manutenção das diversas formas de vidas existentes no planeta. A irrigação usa aproximadamente 70% das águas retiradas do sistema global de rios, lagos e mananciais subterrâneos. Com isso, a agricultura irrigada hoje se faz necessária para garantia da produção de alimentos. Entretanto é preciso avaliar e adequar cada um dos fatores que compõem o sistema de produção, incluindo a eficiência do uso e o manejo da água de irrigação. Com o intuito de avaliar o sistema de irrigação do perímetro irrigado de Poção da Ribeira (PIPR) no ano de 2016, localizado no município de Itabaiana/SE, o presente estudo tem como objetivo geral determinar a eficiência de aplicação da água em doze lotes. Utilizando a proposta descrita por Keller e Karmeli (1974), para se avaliar o sistema de irrigação do perímetro, determinaram-se os coeficientes de uniformidade: de Christiansen (CUC), de Emissão (CUE), Uniformidade absoluta (CUEa), Estática (Us) e a eficiência de aplicação (Ea). Os resultados de CUC, CUE, CUEa e Us foram, respectivamente, 91,45%, 86,41%, 84,05% e 86,48%, valores com parâmetros que variam de bom à excelente. A Ea, teve valor médio considerado aceitável de 82,09%. Os resultados de coeficiente de uniformidade e eficiência de aplicação permitem definir o perímetro como hidraulicamente satisfatório.
The Role of E-government Based Good Governance and Bureaucratic Reform in the Context of Improving the Performance of Government Work Units
Authors: Wahyuni Sri
Published: November 2023

Objective: This research aims to determine the relationship between e-government and good governance, bureaucratic reform on good governance, e-government on performance, bureaucratic reform on performance and good governance on performance.
 
Method: This research method is quantitative through surveys using Partial Least Square (PLS) Structural Equation Modeling (SEM) analysis with data analysis tools using SmartPLS 3.0 software. This research involved 431 government employee respondents who were determined using simple random sampling and were given the obligation to fill out each statement containing statements. The type of variable scale used is an ordinal scale. The rating scale for each statement uses a rating scale technique with a Likert scale type. The measurement scale values used are from 1 to 5, the values on each scale indicate: 1=Strongly Disagree; 2=Disagree; 3= Don't Know; 4 = Agree; 5=Strongly Agree. The online questionnaire is distributed via online social media, the stages of data analysis are the outer model test, namely validity and reliability testing and the inner model test, namely hypothesis testing or significance testing.
 
Results: The results of this study show that E-government has a positive and significant relationship to good governance, bureaucratic reform has a positive and significant relationship to Good Governance. E-government has a positive and significant relationship with performance. Bureaucratic reform has a positive and significant relationship to performance. The implementation of Good Governance has a positive and significant relationship to performance.
 
Conclusion: The benefits that are expected to be accommodated by the results of this research are as a reference and source of information as well as for conducting further research or similar research, in order to provide input for the implementation of e-government based good governance towards bureaucratic reform and its impact on more perfect government performance in the future.
Vacuum polarization in the cosmic-string background
Authors: Grats Yu. V. , Spirin P. A.
Published: November 2023

Within the framework of one-loop quantum gravity, we consider the vacuum polarization effect of the
minimally-coupled massive scalar field near the infinitely-thin straight cosmic string. It is shown that the
massive-field relative contribution to the renormalized vacuum mean of the energy density becomes negligible
at a distance of several Compton lengths.
Institutional Trust as an Object of Political Science Analysis: The Measurement Problem
Authors: Svechnikova Mariya Vladimirovna
Published: November 2023

The problem of trust in political institutions is currently relevant and is becoming the object of research in many scientific fields, including political science. The interest of foreign and Russian researchers is not only the understanding of this phenomenon at the theoretical level, but also its empirical analysis for solving practical problems. In addition to the problem of a conceptual explanation of the concept of “institutional trust”, which has developed due to the theoretical diversity of interpretations of this phenomenon, scientists are faced with the need to choose the best way to collect and measure data (depending on the purpose of a particular study). In this paper, the author focuses on the problem of measuring institutional trust, highlights the key areas of institutional trust analysis, considers their advantages and disadvantages.
INCIDÊNCIA DE INTERNAÇÕES POR INFARTO AGUDO DO MIOCÁRDIO NA PANDEMIA DE COVID-19: UMA REVISÃO INTEGRATIVA DA LITERATURA
Authors: Henrique Pereira da Silva Pedro , Tessari Giulia , Botelho Neves Bruno , Vilela Mareco Breno , Adriano Luiz Thais , Goulart Carneiro Dias Julia , Eduardo Pereira da Silva Lucas
Published: November 2023

O conhecimento sobre COVID-19 torna-se cada vez mais pertinente pois envolve, sobretudo, formas de prevenção e controle da disseminação do vírus, além do uso de equipamentos de proteção individual e medidas de biossegurança. O nível de conhecimento de estudantes durante a formação auxilia nas ações em saúde que visam minimizar os efeitos de uma pandemia como do SARS-CoV-2 e agravos de saúde pública gerados pela má prática assistencial. Neste sentido, este estudo visa descrever o conhecimento relacionado à COVID-19 entre estudantes da área de saúde de uma universidade na Amazônia Ocidental brasileira após declaração de pandemia no novo coronavírus. Trata-se de estudo transversal, descritivo, cuja coleta de dados, por meio de questionário on-line, retornou 182 respostas, a maioria mulheres (65,9%), do curso de enfermagem (24,2%), solteiras (89,0%), idade média 22,39 (DP=4,49) anos, raça/cor não branca (73,6%), no extrato econômico que atende apenas às necessidades básicas (42,9%), que não realizaram formação sobre a COVID-19 (56,0%), tendo a mídia de massa como a principal fonte de informação (91,2%). O nível de conhecimento relacionado à pandemia foi intermediário (68,6%) com alta percepção do risco de morte pela doença (98,9%). Observou-se a necessidade de investimento em formação sobre os assuntos mais atuais, como a pandemia de COVID-19, bem como a oferta e acesso a mais cursos de atualização, com abordagens relacionadas à epidemiologia de doenças emergentes de interesse para a saúde pública e os seus devidos comportamentos preventivos, reforçando a inexistência de tratamento definitivo para COVID-19 e a importância da vacinação contra o vírus.
The role of CGRP monoclonal antibodies in migraine treatment – efficacy, safety, and perspectives for the future: a systematic review
Authors: Tybulczuk Balbina , Rusinowska Barbara , Wawerska Julia
Published: November 2023

Background: Migraine is a widespread headache disorder occurring in every age group. It is divided into two types: chronic and episodic migraine. Many medications have been used in its treatment over the years with different degrees of effectiveness. In recent years, more attention has been given to the role of CGRP monoclonal antibodies for treatment, which are CGRP ligand antibodies (fremanezumab, galcanezumab, eptinezumab) and a CGRP receptor antibody (erenumab).Aim of the study: This study aimed to analyze the efficacy and safety of using CGRP monoclonal antibodies in migraine treatment and discuss CGRP’s role in migraine pathogenesis. Both chronic and episodic migraines were subjects of interest.Material and methods: The search was conducted using the PubMed database. We analyzed articles published in the years 2017–2022. The used keywords were “Migraine”, “Monoclonal antibodies”, “CGRP”, and “Calcitonin gene-related peptide”.Results: The number of articles found depended on the keyword used (“migraine” - 1875 results, “monoclonal antibodies” - 12173 results, “CGRP” - 352 results, and “calcitonin gene-related peptide” - 461 results). A total of 31 articles were quoted in this review. Positive results for treating migraines with CGRP ligand antibodies (fremanezumab, galcanezumab, eptinezumab) and CGRP receptor antibody (erenumab) were observed.Conclusions: The use of CGRP ligand and receptor antibodies seems promising for migraine therapy due to their relatively mild side effects and high efficiency.
Liderazgo escolar en el proceso de aprendizaje en los estudiantes del programa EPJA
Authors: Gómez-Obregón Mirian Verónica , Zambrano-Vera Gabriela Esperanza
Published: November 2023

Para abordar los desafíos académicos y mejorar el proceso de aprendizaje, es necesario involucrar a todos los miembros de la comunidad educativa, identificar las áreas de dificultad de los estudiantes y proporcionar recursos y apoyo adecuados para implementar estrategias efectivas. Entre los problemas que enfrenta el liderazgo escolar en el proceso de aprendizaje, se encuentran la falta de recursos adecuados, el ausentismo escolar, la falta de capacitación para docentes en técnicas de enseñanza innovadoras, la falta de colaboración entre la comunidad educativa y la falta de motivación entre estudiantes y docentes. El objetivo general es desarrollar una estrategia escolar mediante la formación de líderes en el proceso de aprendizaje. La metodología utilizada combina enfoques cualitativos y cuantitativos, y se aplicarán encuestas y entrevistas a docentes y estudiantes para recopilar datos y analizarlos estadísticamente. La población objetivo incluye a 10 docentes y 95 estudiantes los resultados de la investigación muestran que, si bien la mayoría de los estudiantes están satisfechos con las clases y actividades de aprendizaje, también enfrentan desafíos académicos. En conclusión, el liderazgo escolar en el proceso de aprendizaje es crucial para el éxito educativo. La formación de líderes educativos capacitados y la implementación de una estrategia metodológica adecuada pueden mejorar significativamente los resultados académicos y el ambiente escolar del programa de educación para jóvenes y adultos.