bluuebunny/crossref_metadata_2025 huggingface dataset:
Validación de un instrumento de evaluación de proyectos latinoamericanos
Authors: Arteaga-García María Elizabeth , Portalanza-Chavarría Cecilia Alexandra
Published: March 2024

Esta investigación tiene por objeto adaptar y validar el instrumento denominado Perfil de Implementación del Proyecto (PIP) para la evaluación de proyectos realizados en Latinoamérica. Participaron 420 profesionales involucrados, ya sea como líderes o miembros de equipos, en proyectos culminados en el periodo 2020-2021. Como el instrumento fue elaborado en inglés se utilizó un procedimiento de traducción y re-traducción, en el cual participaron expertos profesionales y académicos en gestión de proyectos junto con traductores certificados, para su adaptación a la población hispanoparlante en Latinoamérica. Para el análisis factorial exploratorio se seleccionó el método de extracción de mínimos cuadrados no ponderados, obteniéndose cuatro factores críticos de éxito: Comunicación con el cliente, seguimiento y planeación, alta gerencia, y capacidades técnicas, con coeficientes Cronbach Alpha comprendidos entre .876 y .933. Posteriormente se aplicó el análisis factorial confirmatorio, el cual demostró que el instrumento posee validez convergente y discriminante y, en consecuencia, puede ser utilizado en la academia para futuras investigaciones sobre la gestión de proyectos, y en lo profesional para evaluar el desempeño de proyectos ecuatorianos, contemplando la limitación de que el porcentaje de participación de proyectos de otros países de Latinoamérica en la muestra de estudio fue del 22 %.
Etude du profil linguistique complexe de l’enfant dans les œuvres de Fouad Laroui
Authors: HOUIJ Sirine
Published: March 2024

Le présent article traite du profil linguistique de l’enfant tel qu’il est peint dans un certain nombre d’œuvres écrites par l’auteur marocain contemporain Fouad Laroui. Étant lui-même exposé dans un premier temps à deux cultures différentes (française et marocaine) et ensuite à plusieurs cultures du fait de ses nombreuses expériences d’expatriation, l’auteur témoigne des difficultés rencontrées étant jeune, alors qu’il est issu d’une famille dont les enfants, par le biais des lectures et de l’éducation, sont devenus bilingues. Difficultés qui concernent à la fois le rapport que l’enfant a à sa propre famille et à ce qui devrait être sa langue maternelle, le rapport qu’il entretient avec ses compatriotes, et enfin le rapport qu’il a à la langue française et à ses variétés, et aux natifs de cette langue.
L’imaginaire des langues chez Khatibi. Naissance du bilinguisme dans La Mémoire tatouée
Authors: BASSI Dorra
Published: March 2024

Abdelkébir Khatibi, romancier, critique d’art et sociologue marocain (1938-2009) est une figure incontournable de la réflexion sur le bilinguisme et les rapports entre langue(s) et identité(s). Dans son premier roman autobiographique La Mémoire tatouée (1971), se lit la naissance du bilinguisme chez un jeune Marocain né dans les années trente dans une ville marocaine sous la colonisation française. Dans ce roman, la question de la langue est sous-jacente et se voit être progressivement constituée comme une composante de la question identitaire. Ce sont d’abord les espaces linguistiques qui nous intéressent. Les lieux d’apprentissage mais aussi les chemins vers l’école : entre la bibliothèque paternelle, l’école coranique et l’école française puis le collège, se dessinent à travers le récit de Khatibi plusieurs imaginaires qui parfois se heurtent et plus souvent se croisent. Et c’est petit à petit un lien rhizomique entre les langues et ce qu’elles véhiculent qui se tisse. C’est aussi la construction du sujet et plus particulièrement de l’instance énonciative qui se dédouble au fil du texte et qui se positionne à mi-chemin entre l’histoire personnelle et l’histoire collective. Si le titre du roman est La Mémoire tatouée, Khatibi se presse d’y accoler un sous-titre : Autobiographie d’un décolonisé. Peut-on lire dans ce roman une illustration de la créolisation telle que définie par Glissant ?
Fermina Márquez (1910) de Valery Larbaud ou le récit d’une adolescence plurilingue
Authors: MONTIBELLER Clara
Published: March 2024

Fermina Márquez est centrée sur l’aura dont l’héroïne éponyme jouit auprès des adolescents qu’elle rencontre dans un établissement scolaire parisien. Jouant avec ces voix et ces amours adolescentes, le récit met en scène un hétérolinguisme franco-espagnol, nous offrant une représentation attachante du bilinguisme en milieu scolaire. Bien que la juxtaposition des langues soit inséparable d’un choc des cultures, sous la plume de Larbaud, la polyglossie et le pluriculturalisme sont portés par un discours résolument xénophile puisque l’éloge de la langue espagnole encourage sa diglossie. Au-delà de cette simple thématisation, Larbaud a dramatisé la pluriglossie puisque le bilinguisme franco-espagnol est concurrencé par les langues antiques.
Entretien avec Denis Lachaud. « L’idée de départ pour J’apprends l’allemand n’était pas du tout l’Allemagne, ni même les langues ; c’était d’écrire un roman sur la place du silence dans l’héritage familial »
Authors: SAMPAGNAY Louise
Published: March 2024

Cet échange avec Denis Lachaud sur la place de l’apprentissage des langues dans ses romans, en particulier J’apprends l’allemand (1998), met en évidence la porosité entre autofiction et biographie langagière au sens où on l’entend depuis les années 1980 dans le champ de la didactique des langues. Trois problématiques centrales sont abordées dans l’entretien : d’abord, la construction fictive d’une enfance entre les langues, et la prise de conscience par l’auteur d’un plurilinguisme familial réel mais oublié ; ensuite, la représentation de la limite en littérature plurilingue, liée à la dimension arbitraire de la frontière politique et culturelle ; enfin, les recoupements entre hétéronormativité et monolinguisme en regard de l’homosexualité et du plurilinguisme, et leurs représentations chez des personnages adolescents.
Construindo comunidades saudáveis
Authors: ALZATE LÓPEZ Yeimi Alexandra , ALIAGA Marie Agnès , ALMEIDA FIGUERÊDO Lívia , LIMA DUARTE COUTINHO Andrea , DE OLIVEIRA CARNEIRO Ianei , ARGIBAY Hernán Darío , KHALIL Hussein , COSTA Federico , LUSTOSA Ricardo , MOGAJI Hammed Oladeji
Published: March 2024

A urbanização sem planejamento é um dos principais desafios da saúde pública. Em cidades do Brasil como Salvador-BA, uma grande proporção da população de baixa renda, que mora em áreas periféricas enfrenta altas incidências de doenças infecciosas, falta de acesso a serviços básicos como o saneamento, água potável, serviços de saúde, desemprego e violência social. Estes aspectos nos permitiram, em uma primeira fase de estudos, discutir estes cenários como casos de injustiça ambiental. O projeto “Construindo Comunidades saudáveis em favelas urbanas brasileiras” liderado pelo Instituto de Saúde Coletiva da UFBA, em parceria com o Instituto Gonçalo Muniz (IGM/Fiocruz), London School of Hygiene - Tropical Medicine, Universidade de Liverpool e Universidade de Lancaster (Reino Unido) e a Universidade de Yale (Estados Unidos), se propõe construir ações planejadas com adaptação ao contexto local, de forma participativa junto com atores da comunidade. A pesquisa interdisciplinar inclui pesquisadores de diversas áreas: ecologia, epidemiologia, ciências sociais, entre outras e adota os princípios da Pesquisa Participativa baseada na comunidade (PPBC). A proposta é de trabalhar coletivamente, em conjunto com atores locais, no desenvolvimento da pesquisa e no desenho, implementação e avaliação de intervenções que mitiguem o risco de doenças infecciosas, incluindo doenças negligenciadas (leptospirose, infecções entéricas, zika, dengue, chikungunya, tuberculose, covid-19, gonorreia, clamídia e HIV), em quatro comunidades de Salvador. Por esse motivo, propõe-se nesta apresentação, refletir acerca dos desafios de adotar a perspectiva da PPBC, as possibilidades e contradições da interação e da tomada de decisão nas fases iniciais da pesquisa, a qual se espera que seja equitativa entre pesquisadores, a comunidade e outros atores, além de considerar os desafios do engajamento e mobilização comunitária frente as limitações impostas pela Pandemia do Covid-19.
L’œuvre d’art est violence – La violence n’est pas une œuvre d’art
Authors: FÖLLMI Beat
Published: March 2024

Comme l’a démontré Gérard Pirlot, la violence est inhérente à l’acte artistique et à l’œuvre d’art qui en résulte. L’histoire de la musique en Occident est, pour une bonne partie, une manifestation de cette violence/“biolence”, par exemple à travers l’expérience de la dissonance et de son émancipation. Pourtant la consubstantialité existant entre œuvre d’art et violence ne pourra pas mener à un “mal-entendu” : que la violence elle-même serait l’œuvre d’art. C’est exactement ce qui s’est produit dans une interview que le compositeur Karlheinz Stockhausen a donnée en 2001, cinq jours après les attentats contre les tours jumelles à New York. En dépit du lynchage médiatique qui a suivi immédiatement ses propos, Stockhausen n’a pas dédaigné la mémoire des victimes. Le compositeur était plutôt fasciné par la radicalité inconditionnelle des actes terroristes qu’il compare à ses propres œuvres musicales, susceptibles de transformer les auditeurs. À cet égard, les attentats du 11 septembre étaient pour lui « l’œuvre d’art la plus grande qui puisse exister dans le cosmos entier ». Il commet ainsi une confusion fondamentale : les victimes assassinées par les terroristes n’étaient pas le “public” que l’“œuvre d’art” viserait à transformer, mais les terroristes utilisent abjectement les êtres humains comme “matériau” de leurs abominables crimes. En dépit de leur perfection (“esthétique” et technologique) et de leur impact médiatique, ces actes ne seront jamais une œuvre d’art mais resteront un crime tout court.
Prométhée à Tarajal
Authors: MORALES MONTORO Antonio Miguel
Published: March 2024

La pièce, qui actualise le mythe de Prométhée, met en scène la violence de la Garde civile qui, le 6 février 2014, utilisa du matériel antiémeute pour empêcher un groupe de 200 migrants, provenant principalement de l’Afrique Subsaharienne, de débarquer sur la plage de El Tarajal à Ceuta. Quinze migrants perdirent la vie à quelques mètres de la plage.
A brooch with a name stamp from Győr-Ménfőcsanak-Széles-földek (Pannonia, Hungary)
Authors: Sáró Csilla
Published: March 2024

Name stamps occasionally appear on early Roman Period bow brooches, such as Aucissa brooches, Nertomarus brooches, brooches with side knobs (Scharnierflügelfibeln), and rosette brooches (Kragenfibeln, Distelfibeln, Flache Distelfibeln). Aucissa brooches are known from the territory of the whole Roman Empire and were produced in multiple workshops, while the other types were typical of the western parts, having been manufactured primarily in the western provinces. According to current research, the 55 bow brooches from Győr-Ménfőcsanak-Széles-földek belong to different western types. The only stamped brooch is a fragmentary Nertomarus brooch with an abbreviated NERTOMARVS stamp (NORV). This brooch could reach Pannonia from the place of production in different ways. One option is that the brooch travelled with its owner, a military person, or someone who accompanied the troops.
Household pottery of an urban noble house and craftsmen in Visegrád
Authors: Góra Bence
Published: March 2024

In 2003–2004, the King Matthias Museum in Visegrád conducted archaeological excavations at 5 Rév Street, Visegrád. The fieldwork brought to light, besides an already known late medieval house and a glass workshop of outstanding importance, some more buildings and the excellently preserved part of a street pavement. The study presents the pottery finds obtained by the excavations.
The fort of Ad Mures (Ács, Komárom-Eszergom County, Hungary)
Authors: Simon Bence , Borhy László , Bartus Dávid , Olasz Rita Helga , Szabó Melinda , Müller Ákos , Peng Mátyás , Czajlik Zoltán , Hümpfner Dániel
Published: March 2024

The Roman auxiliary fort of Ad Mures (Ács-Bumbumkút, Komárom-Esztergom County, Hungary) has recently been studied intensively using geophysical surveys and a planned excavation by the team of the Institute of Archaeological Sciences of the Eötvös Loránd University. The paper presents the preliminary results of these investigations, focused on the layout of the fort and the relative chronology of the site, based on the data collected during the 2023 excavation. Results indicate several analogies with the fort of Ad Statuas (Ács-Vaspuszta).
Northwest Transdanubia from the end of the Early Bronze Age until the Koszider Period
Authors: Melis Eszter
Published: March 2024

Review article of the PhD dissertation submitted in 2023 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest, and written under the supervision of Gábor V. Szabó. The dissertation investigated the processes taking place at the end of the Early and in the Middle Bronze Age in northwest Hungary, predominantly in Győr-Moson-Sopron County, based on sites at Nagycenk, Hegyeshalom, Enese, Győr-Ménfőcsanak, and Mosonszentmiklós. This region between the Devín Gate and the confluence of the Rába and Danube rivers is important for European research on prehistory, as it could have been a gateway between the Carpathian Basin and the western parts of Central Europe. The complex statistical evaluation of the collected archaeological finds and their contexts has revealed the diversity of the material culture (Gáta–Wieselburg, Kisapostag, Transdanubian Encrusted Pottery Culture) and mortuary practices (inhumation and cremation burial rites, diverse patterns of grave furnishing) in the study area and period. In addition, a spatial analysis of the sites indicated a change in the settlement pattern between 2200 and 1500 BC. The typochronological analysis and the radiocarbon data helped specify the chronology and refine the connections maintained with Central European territories.
GeoMx Digital Spatial Profiler (DSP) Protocol v2 - University of Minnesota TMCs v2
Authors: J Niedernhofer Laura
Published: March 2024

The nanoString GeoMx‱Digital Spatial Profiler (DSP) is a platform that allows high-plex profiling at the protein and RNA level, providing spatial and temporal assessment of tumors in frozen or formalin-fixed paraffin-embedded limited tissue sample. The following protocols/manuals were used at the University of Minnesota TMCs in collaboration with the University of Minnesota Genomics Center.
Janelia Atalanta series plasmid cloning v2
Authors: Stern David
Published: March 2024

The Janelia Atalanta plasmids allows simple cloning of a gRNA and homology arms for CRISPR/Cas9 mediated homology directed repair in Drosophila. Gateway-compatible arms are synthesized with appropriate attL recognition sequences and homology arms required for homology directed repair. One, or two, of the arms also encodes a sgRNA flanked by tRNA sequences, which is expressed at high levels from a U6 promoter. The sgRNA is spliced out of the transcript by endogenous tRNA maturation cellular machinery.
Library positive controls (LPCs) prepared on the Bravo NGS Workstation v1
Authors: Schmidt Anna , Nagel Sarah , Meyer Matthias
Published: March 2024

Protocol for the preparation of library positive controls (LPCs) in FluidX tubes using the Bravo NGS Workstation. LPCs are used as part of the library preparation workflow of the Ancient DNA Core Unit of the MPI-EVA.
Let's Hear Children's Emotions: The Play-Based Psychoeducation Program for the Socio-Emotional Development of Primary School Children
Authors: Öztekin Gülçin Güler , Turp Hurızat Hande , Ata Samet
Published: March 2024

The acquisition of empathy, emotional literacy and prosocial skills is important for children's social, emotional and moral development. If these skills are supported through play in children, their acquisition will be faster and easier. Therefore, in this study, the Play-Based Socio-Emotional Psychoeducation Program including empathy, emotional literacy and prosocial skills was prepared and its effect on children was examined. The present research was the pretest-posttest quasi-experimental study. The sample of the study consisted of primary school students between the ages of 7-10. 23 children were included in the experimental group and 23 children were included in the control group. An average of 45 minutes of practice was applied to the experimental group for 10 weeks. The findings of the study showed that there was an increase in empathy, emotional literacy, and prosocial skills of the children in the experimental group after the application, but there was no change in their behaviors. These results provided evidence that the program was effective on these skills. It can be said that the current study will shed light on field workers and the play-based psychoeducation program will be an effective program that they can integrate into their practices.
Co-Production Boundaries of Nature-Based Solutions for Urban Regeneration: The Case of a Healthy Corridor
Authors: Caitana Beatriz , Moniz Gonçalo Canto
Published: March 2024

Co-production, rooted in public collaborative management (Ostrom, 1996) or science and technology (Jasanoff, 2013) evolution, has demonstrated its innovative and transformative character within participatory processes. However, there is little empirical evidence that scrutinises these contexts of interaction. Equality of partnership in many cases is used as a discursive rhetoric that seeks to prescribe co-production above any difficulty, uncertainty, conflict, or unwanted situation. As a starting point, our proposal considers co-production as a social practice, composed of multiple layers and different participatory processes, activities, and strategies. Grounded in co-production approaches, the study draws upon the ongoing evaluation findings of the European project URBiNAT, which focuses on inclusive urban regeneration through nature-based solutions. The qualitative methods of evaluation (interviews and participant observation), applied during the co-production activities in the city of Porto (Portugal), provide evidence of how the various stakeholders—elected politicians, citizens, technicians, and researchers—participate in the co-production dynamic. The boundaries of a multi-stakeholder process are revealed with the goal of implementing healthy corridors in peripheral neighbourhoods. The intended evaluation analysis lies in the techniques, the agents, the dynamics, the knowledge, and the degrees of co-production. This analysis will contribute to the lack of explicit consideration of the impacts of nature-based solutions in urban regeneration pathways, especially those related to the social fabric underlined in Dumitru et al. (2020).
De Espiritistas y Curanderos Debates sobre medicina tradicional y salud mental latina en Texas y Nueva York durante los 1960
Authors: López Carrillo Ximena
Published: March 2024

In October of 1963, John F. Kennedy signed the Community Mental Health Act to expand preventive and early mental healthcare to historically underserved communities that overwhelmingly belonged to minority groups. Suspicious of the role that psychologists and psychiatrists had played in the pathologization of racial and ethnic minorities since the 19th century, Latine patients refused to use the community mental health centers and instead continued resorting to traditional healers for emotional support. This article traces the professional debates about the relationship between traditional healing and mental health carried out in 1960s Texas and New York. Following both contexts, I argue that the rising political mobilization among Latines in both states and the popular cries to restrict Mexican immigration into the United States shaped the professional attitudes toward traditional healing. These debates led to two contrasting policies. One that celebrated spiritists and incorporated them into the arsenal of mental health providers in New York City’s Puerto Rican neighborhoods. Another one that berated curanderos and called for their regulation due to their proximity to indigeneity, and foreignness, as well as their popularity among lower-class Mexican migrants arriving to Texas.
Writing, Rioting, and Righting Como Negra: A Testimonio of Black Latinx Erasure in Bilingual Education
Authors: Cioè-Peña María
Published: March 2024

In this autoethnography, María Cioè-Peña recounts her experiences of Black erasure in bilingual education in US schools, where the focus is on language and an imagined mixed-race collective, centering culture to circumvent race and treating language as connective yet racially neutral. But languages and how language users are perceived are not race-neutral constructs. Black erasure in bilingual education upholds anti-Blackness and model minority narratives in education and results in tangible exclusion and oppression for Black bi/multilinguals. Supported by theory and history, Cioè-Peña recounts key moments that contributed to her internalization of anti-Black ideology/rhetoric and respectability politics as a bilingual Black Latina, manifesting in the “taming” of her tongue and cultural identity. Through her testimonio, she sheds light on the erasure of Black students in bilingual education programs and research.
Pursuing Language Through Critical Metalinguistic Engagement
Authors: Jones Renata Love , Proctor C. Patrick
Published: March 2024

In this article Renata Love Jones and Patrick Proctor introduce the notion of pursuing language to engage in critical dialogue about the nature and focus of language and literacy education in multilingual and multicultural contexts. A persistent threat in language and literacy education is standardization that constrains how language and literacy are operationalized, which further limits how children can bring their unique communicative practices into schools and classrooms. In response, the authors describe pursuing language as a state of being responsive in our language and literacy instruction, with the goal of developing literacy skills through culturally affirming and anti-oppressive practices. They operationalize this pursuit of language in classroom contexts by delineating a framework of critical metalinguistic engagement. The article begins with a theory of languaging and goes on to unpack critical metalinguistic engagement by each of its component parts—critical, metalinguistic, and engagement—and concludes with an argument for being intentional about pursing language through relationships and dispositions that affirm language diversity in educational practice and research.
Continuity and dialogue in the constitutional and legal development of Russia: reflections in the context of the scientific heritage of E. I. Kozlova
Authors: Kabyshev S. V.
Published: March 2024

The article is an experience of reflection on the meaning and nature of continuity in the constitutional development of the institutions of Russian statehood in the context of the ideological and scientific heritage of Professor E. I. Kozlova. Defending the position according to which continuity is not an imperative-determinant, but a dialogic (discursive) characteristic of constitutional and legal development, involving the identification and interpretation of political and legal traditions, ideals, values in their refraction through the prism of specific historical conditions and perceived hopes, aspirations for the future, the author sees in continuity a source and institution of sovereign self-organization of the people. Following these methodological approaches, which are being confirmed, substantiation in the works of Professor E. I. Kozlova, who managed to remain modern and timely in different historical eras, the author reveals the actual significance of a number of ideas of Professor E. I. Kozlova in relation to understanding the essence of the Constitution, constitutional law in order to gain a confident constitutional future of Russia in legal science, education, regulation and legal practice.
New International Federation of Gynecology and Obstetrics ovulatory disorders classification system 2022. Diagnostic assessment of ovulatory dysfunction
Authors: Kovalyova Yuliya V.
Published: March 2024

Until recently, researchers and clinicians have used the World Health Organization classification of ovulatory disorders (1973), which was based on the levels of gonadotropins and estrogens in the blood serum (mainly follicle-stimulating hormone) and classified ovulatory disorders depending on the hypothalamic-pituitary-ovarian axis dysfunction levels.
This review article presents a new classification system for ovulation disorders developed by the International Federation of Gynecology and Obstetrics (FIGO) in 2022. The first level of this classification system is based on an anatomical approach (hypothalamus, pituitary gland, ovaries), which is complemented by a separate category for polycystic ovary syndrome. At the second level, each anatomical category is classified according to the putative etiopathogenetic mechanisms underlying ovulation disorders. The third level suggests the presence of specific nosologies, which represent the direct cause of ovulation disorders. This new classification should be used after a preliminary examination that reveals the presence of an ovulation disorder. This review discusses various ovulation disorders and provides tools for their diagnosis in accordance with international guidelines and domestic recommendations.
Serotonin receptor and serotonin transporter expressions in the placental villous tree in gestational diabetes mellitus
Authors: Bettikher Ofelia A. , Belyaeva Olga A. , Dukovich Albina I. , Vorobeva Olga M. , Tral Tatiana G. , Tolibova Gulrukhsor Kh. , Bart Victor A. , Kogan Igor Yu. , Zazerskaya Irina E.
Published: March 2024

BACKGROUND: The serotonergic system during pregnancy plays an important role not only in carbohydrate metabolism, but also in the laying and regulation of the fetoplacental complex, growth and development of the fetus. The study of the expression of placental serotonin 5-HT2A receptor and serotonin transporter (SERT) in gestational diabetes mellitus is foremost for scrutinizing the pathogenesis of perinatal complications, as it may allow for finding new opportunities for their prevention and correction.
AIM: The aim of this study was to compare the expression patterns of the serotonin 5-HT2A receptor and SERT in placental tissue in gestational diabetes mellitus and in normal pregnancy.
MATERIALS AND METHODS: This comparative cohort study included pregnant women with gestational diabetes mellitus (n = 6) and patients with normal pregnancy (n = 10). The expression of serotonin 5-HT2A receptor (Abcam, USA) and SERT (Bioss Antibodies, USA) was studied in placenta samples from the both study groups by immunohistochemical method. Morphometric analysis was performed using the VideoTest-Morphology 5.2 program (Videotest Ltd., Russia).
RESULTS: The relative area of SERT expression in the placenta in gestational diabetes mellitus was higher compared to normal pregnancy (p 0.001). The relative areas of expression of the serotonin 5-HT2A receptor in the placenta did not differ between the study groups (p = 0.5).
CONCLUSIONS: Higher SERT expression in the placentas of patients with gestational diabetes mellitus compared to those from women with normal pregnancies may reflect the level of tension of compensatory mechanisms in gestational diabetes mellitus and the effect of insulin therapy on these mechanisms.
The study of indicators of authenticity and goodness of flowers of narrow-leaved lavender (Lavandula angustifolia L.)
Authors: Whaley Andrey K. , Whaley Anastasia O. , Zhokhova Elena  V. , Suloev Ivan S. , Abdumazhidova Istora  O. , Farmanova Nodira T. , Yakovlev Gennady P.
Published: March 2024

The study is dedicated to the analysis of the cultural and medicinal plant Lavandula angustifolia Mill. from the Lamiaceae Martinov family. The plant is widely used in the food and perfume-cosmetic industries, as well as in traditional medicine for treating various diseases including rheumatism and migraines. The research focuses on the analysis of phenolic compounds and terpenoids, which are the main pharmacologically active components of narrow-leaved lavender. Phenolic compounds include flavonoids, phenolic acids, and coumarins, while terpenoids such as linalool and linalyl acetate are responsible for the aromatic essential oil. The experiment involved studying the quantitative content of flavonoids, chromatographic analysis of secondary metabolites, and microscopic analysis of the structure of narrow-leaved lavender flowers. The obtained data expand the nomenclature of pharmacopoeial herbal raw materials. The quantitative content of flavonoids and the profile of major polyphenolic secondary components have been established. These results can serve as a basis for standardization and quality assessment of narrow-leaved lavender flowers, as well as for further phytochemical and pharmacological research.
Use of concomitant anesthesia (endotracheal anesthesia and femoral nerve block) in cardiac surgery: a prospective, cross-sectional study
Authors: Klepcha Tatyana I. , Dudko Vladimir A. , Lipnitskiy Artur L. , Marochkov Alexey V.
Published: March 2024

BACKGROUND: Regional anesthesia reduces pain impulse transmission, which reduces hormonal and metabolic responses to operational stress. No studies have reported on the use of combined anesthesia, such as endotracheal anesthesia and femoral nerve block, in cardiac surgery.
OBJECTIVE: To determine the efficacy of combined anesthesia by analyzing the cortisol, glucose, and lactate levels in cardiac surgery.
MATERIALS AND METODS: Prospective cross-sectional study was conducted. The study included 60 cardiac surgery patients. The patients were divided into two groups: group 1, with endotracheal anesthesia and femoral nerve blockade, and group 2, with endotracheal anesthesia (control group). All patients underwent aortocoronary bypass grafting under artificial circulation conditions. Cortisol, glucose, and lactate levels at the five stages of the perioperative period were investigated.
RESULTS: Data analysis showed that the cortisol level of patients with combined anesthesia was significantly 1.2 times lower (p=0.042) than that in the control group in step 2. Glucose levels were significantly lower in the combined anesthesia group by 1.28 times (p=0.0017) than in the control group in step 4 and significantly lower by 1.2 times (p=0.0016) in step 5. Additionally, lactate level was significantly lower in the combined anesthesia group than in the control group in step 4 by a factor of 1.3 (p=0.03) and in step 5 by a factor of 1.35 times (p=0.005).
CONCLUSION: The determination of cortisol, glucose, and lactate levels can be used as a component of endocrine-metabolic anesthesiological monitoring when performing cardiac surgery under artificial circulation conditions. Stable parameters of endocrine-metabolic monitoring were established using both anesthesia methods. The use of femoral nerve block in combined anesthesia reduces stress response to surgery.
Modern methods of regional and postoperative anesthesia during cesarean section: a literature review
Authors: Korobka Miriam N. , Pichugina Valeria M. , Khazieva Anzhelika R. , Borisov Alexandr V. , Stepanova Anastasiya V. , Safina Diana A. , Strelnikova Polina A. , Udagova Aishat A. , Tarasenko Elena A. , Grezin Aleksey G. , Mukhamadiyarova Karina R. , Filippov Artem A. , Krestyaninova Victoria V.
Published: March 2024

The number of cesarean section (CS) deliveries increases annually in Russia. General anesthesia involves certain risks, including difficult or unsuccessful intubation, aspiration, and infectious and thromboembolic complications. Therefore, regional anesthesia is the method of choice for CS. To date, choosing the most effective method of regional anesthesia remains challenging, including in the postoperative period. Thus, this review aimed to compare the effectiveness of regional anesthesia methods used in CS and identify the most preferred ones for use in clinical practice. The authors conducted a literature search in the electronic databases PubMed (MEDLINE), eLibrary, and Google Scholar using the following keywords and their combinations in English and in Russian: «cesarean section», «neural morphine», «regional analgesia», «epidural analgesia», «peripheral nerve block», nerve block», «paravertebral block», «cesarean section», neuroaxial use of opioids», «regional analgesia», «epidural analgesia», «peripheral nerve blockade», «blockade», and «paravertebral blockade». The search results revealed 3 558 in the PubMed database, 94 in eLibrary, and 2 662 in Google Scholar. The results show that the neuroaxial administration of opioids remains the gold standard of pain relief after CS; however, information on the analgesic effectiveness of new blockades, such as anterior block of the quadratic lumbar muscle and block of the muscle straightening the spine, continues to accumulate.
Sella Turcica Üzerine Yapılan Bilimsel Çalışmaların Bibliyometrik Analizi
Authors: Özandaç Polat Sema , Sönmez Elif İpek , Tunç Mahmut , Göker Pınar
Published: March 2024

Sella turcica, os sphenoidale’de yer alan, merkezinde bulunan boşluğa glandula pitutiaria’nın yer aldığı ve radyolojik görüntülerde referans noktası olarak da kullanılan önemli bir anatomik yapıdır. Bu çalışmanın amacı sella turcica ile ilgili yapılmış ya da sella turcica’nın da içinde yer aldığı çalışmaların bibliometrik analizini yapmaktır. Bu amaç doğrultusunda Web of Science Core Collection veritabanından veriler (5066 adet “sella turcica” anahtar kelimesini içeren yayın) alınarak VOSviewer görsel bilimsel haritalama yazılım progamında işlenmiştir. Program çıktısı olarak alınan bibliometrik veriler ile (ülke, yayınevi, yazar, yayın, anahtar kelime, terim gibi) tablo ve bilimsel haritalara aktarılarak detaylı olarak analiz edilmiştir. Bu veriler ışığında Avrupa ülkeleri ve ABD’nin bu konuda yapılan bilimsel çalışmalarda öncü rol oynadığı görülmüştür.Ayrıca “cerrahi”, “nöroloji” ve “endokrinoloji” alanlarında çalışmaların yoğunlaştığı kaydedilmiştir. Yaptığımız bu bibliometrik analizin alanda çalışan klinisyenlere ve akademisyenlere hem mevcut durum hakkında bilgi vereceği hem de ileride yapılabilecek çalışmalar için fikir verebileceği kanısındayız.
Beyond Human Judgment: Exploring the Impact of Artificial Intelligence on HR Decision-Making Efficiency and Fairness
Authors: Khair Md Abul , Mahadasa Ravikiran , Tuli Ferdouse Ara , Ande Janaki Rama Phanendra Kumar
Published: March 2024

This study aims to evaluate the impact of artificial intelligence (AI) on the efficiency and fairness of human resources (HR) decision-making. The key goals are to determine how artificial intelligence improves decision-making efficiency, investigate the fairness issues involved in AI-driven human resource practices, and make policy suggestions for engaging in ethical HR practices. The approach utilized is known as secondary data analysis. It is used to synthesize insights and patterns by pulling upon previously published literature and empirical investigations; even though artificial intelligence technologies present an opportunity to optimize human resource operations and improve organizational performance, significant findings demonstrate that these technologies also create ethical problems connected to algorithmic biases and an absence of transparency. Regulatory oversight, ethical standards, data governance, diversity and inclusion programs, and constant monitoring and assessment are some of the policy implications that should be considered to guarantee responsible deployment of artificial intelligence in human resource contexts. When it comes to human resource decision-making, companies can embrace the revolutionary potential of artificial intelligence (AI) while maintaining ethical standards if they prioritize justice, openness, and accountability.
RECOVERY OF BORON WASTES WITH INORGANIC ACID
Authors: Yoğurtcuoğlu Emine
Published: March 2024

Approximately 73-74% of boron mineral reserves all over the world are located in the Western Anatolian region of Turkey, in the provinces of Eskişehir, Kütahya, Balıkesir, and Bursa. The most intense minerals extracted from these fields are colemanite, ulexite, and tincal minerals, respectively. The general principle in the recovery of these minerals is to extract the raw ore and obtain it by size reduction processes of concentrates in high grade. In addition to concentrates, boric acid (H3BO3) production is also possible in Balıkesir and Kütahya. The production of this acid in question includes a series of processes from dissolution with sulfuric acid at high temperatures to crystallization. In this study, except for the aforementioned high concentrations, boron recovery from clay waste, which is high in boron content and is collected from plant waste ponds, is investigated. For this purpose, ulexite-colemanite-containing slime wastes of the Bigadiç (Balıkesir) Plant were dissolved in 7% solids at 60°C in different sulfuric acid concentrations (1-6% H2SO4) and were obtained with 83-97% B2O3 recovery. When the boron wastes are evaluated, issues such as the discovery and establishment of a new waste pond/dam will be solved, the valuable content in the wastes will be recovered, and the environmental problems of boron and other contents in clay will be eliminated. This article includes information about the characterization of the structure by considering the dissolution of boron and other compounds, as well as obtaining boric acid from inorganic acid and boron wastes.
Correlation of Peat Water and Skin Disease Complaints in the Community of Handil Sohor Village, Indonesia
Authors: Nawan Nawan , Wulandari Intan Wahyu , Alexandra Francisca Diana , Handayani Septi
Published: March 2024

Background The use of peat water as a water source, especially in areas with large peatlands, such as in central Kalimantan, is still common. Handil Sohor is one of the villages in Central Kalimantan Province where the community still uses peat water for daily needs. Peat water, which does not fulfill the health requirement, is used for daily needs such as bathing and washing; therefore it can cause health complaints on the skin. Purpose of this study was to determine the correlation between peat water and skin disease complaints that happened in society. Methods The research type used is an analytical descriptive method with a cross-sectional design. The samples used in this research are 116 people taken with the purposive sampling technique and peat water samples. This research is conducted in June - October 2022. Results This research results showed that in a society with a contact duration of more than 60 minutes/day experienced skin disease complaints are 32 respondents in a society with a frequency of using peat water more than three times/day who experienced skin disease complaints are 41 respondents. The statistical test results through the chi-square test obtained the results for the contact duration variable with scores (p-value = 0,007) and (OR = 2,857). Conclusions Contact duration and frequency of use of peat water correlate with skin disease complaints.
Drilling Down for Answers: Unmasking the Impact of Oil and Natural Gas Activity on Crime Rates in Texas
Authors: Shaw Callie D.
Published: March 2024

This article delves into the impact of oil and natural gas (ONG) production on the incidence of Part I violent crimes in Texas. Texas holds a prominent position in the energy industry, contributing to 43% of the nation's crude oil production and 26% of its natural gas production (EIA, 2021). However, alongside ONG operations come significant societal changes, including a rise in various social issues, including criminal activities. While prior research has explored the consequences of ONG-related transformations on crime rates through perceptual and economic studies, there is a scarcity of studies that investigate the intricate relationship between ONG activities and crime patterns, particularly in the Texan context. To bridge this research gap, this study employs residual change scores and multiple linear regression techniques to scrutinize county-level shifts in ONG activity and Part I violent crime incidents during the period spanning 2009 to 2019 across Texas ONG-producing counties. The findings derived from this investigation unveil a noteworthy association between six dynamic ONG measures and the alteration in specific known Part I violent crimes. This study makes a noteworthy contribution to the existing body of knowledge concerning rural crime and boomtown dynamics as it stands as the inaugural examination utilizing residual change score analysis to determine whether ONG activity indeed contributes to any variations in known Part I violent crime rates. By scrutinizing the intricate connection between energy production and crime, this research aids in fostering a better understanding of the social implications of ONG activities in resource-rich regions, particularly within Texas.
Fundamentals of Pharmacy (FOR GPAT & NIPER)
Authors: Gohil Chiragkumar J.
Published: March 2024

This book is based on the core module of pharmacy syllabi recognise by the A.I.C.T.E and various Technical Universities. This book is going to helpful to the students for various competitive examination including GPAT and NIPER.The material in this text covers basic terminology, principles and fundamental concepts of pharmacy so UG and PG students as well as pharmacy professionals shall be benefited by this book. I have tried to make a compact book instead of the bulkier one. To keep the size of the book, this book do not cover the detail syllabus of all subjects but only covers the most important topics and phenomena of respected subjects. Book contains the flow chart like presentation of topics, so that it can be easily grasped by students and they can quickly study and revised the important topics of various subjects of pharmacy.
Therapeutic landscape of natural products and emulgel in psoriasis
Authors: Doke Rohit , Matade Ritik , Harne Swarup , Kale Sakshi , Ponde Yashodhan , Naik Tejas , Lamkhade Ganesh
Published: March 2024

Psoriasis, characterized by immune-mediated inflammation triggered by dysfunctions in the immune system, manifests in various skin areas with elevated plaques presenting as common symptoms. Traditional psoriasis treatments often incorporate plant-based remedies, which, although safer, are predominantly hydrophobic, limiting their permeation and absorption into the skin. To address these challenges, researchers have turned to emulgels as drug delivery systems. Emulgels, combining the properties of both emulsions and gels, effectively solubilize hydrophobic drug molecules, enhancing their absorption through the skin. Emulgels shows several advantages including easy application and removal, emollient properties, non-greasiness, cosmetic appeal, and excellent penetration capabilities.

This review emphasizes the significance of herbal drugs in psoriasis therapeutics and explores the utilization of emulgels as a delivery system for herbal extracts and constituents in psoriasis treatment. By highlighting the potential of emulgels in enhancing the delivery of herbal remedies for psoriasis management, this review offers insights into novel approaches to address the challenges associated with traditional psoriasis treatments.
Impact of formulation excipients on skin barrier functions: A review
Authors: Panwar Aakash Singh , Rathore Priyanka
Published: March 2024

The skin serves as the primary barrier protecting the body from external insults, and its integrity is crucial for overall health. Formulation excipients, including emulsifiers, thickeners, and preservatives, commonly used in skincare products, can significantly influence skin barrier function and permeability. This review evaluates the impact of these Excipients on skin barrier function using biophysical measurements such as Trans-epidermal Water Loss (TEWL), skin hydration, and trans-epidermal water content. Furthermore, it discusses the potential implications of excipient-induced alterations in skin barrier function for skin health and tolerability.
Searching for a Safe Harbor: Fiscal Policy Responses in Small Island Developing States
Authors: Clayton Khamal , Rosenblatt David
Published: March 2024

Over the last two decades, there has been a growing empirical literature to test whether governments fiscal policies systematically respond to changes in the level of debt-to-GDP. Most research has focused on advanced and emerging economies and has overlooked developing countries, especially small island developing states (SIDS). While Caribbean fiscal reaction functions have been estimated in the literature, this paper fills a gap by broadly including all SIDS in the analysis. We find that weak fiscal sustainability has been maintained, but mostly due to the more recent period of the analysis, and with the exclusion of the outlier of São Tomé and Principe. The magnitudes of the coefficient of the increasing primary balance in response to increasing debt-to-GDP is in line with estimates from the literature including, for example, past work on Caribbean SIDS. Two novel findings are that extreme weather events are indeed associated with deteriorations in the primary fiscal balance, and that primary balances may respond pro-cyclically to economic booms and acyclically or counter-cyclically to economic busts.
Neuroprotective and anti-inflammatory effects of eicosane on glutamate and NMDA-induced retinal ganglion cell injury
Authors:   Department of Ophthalmology, the First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong Province, China; Changde Hospital, Xiangya School of Medicine, Central South University (the First People’s Hospital of Changde City), Changde 415000, Hunan Province, China, Wu Zhen-Kai , Zhu You-Lin ,   Changde Hospital, Xiangya School of Medicine, Central South University (the First People’s Hospital of Changde City), Changde 415000, Hunan Province, China, Xiong Meng-Qin ,   Changde Hospital, Xiangya School of Medicine, Central South University (the First People’s Hospital of Changde City), Changde 415000, Hunan Province, China, Zhong Jing-Xiang ,   Department of Ophthalmology, the First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong Province, China
Published: March 2024

AIM: To investigate the protective effects, antioxidant potential, and anti-inflammatory mechanisms of eicosane on glutamate-induced cell damage and on N-methyl-D-aspartate (NMDA)-induced retinal ganglion cell (RGC) injury in a mouse model of glaucoma.
METHODS: The protective effects of eicosane on the rat R28 retinal precursor cell line were assessed using cell counting kit-8 assays and Hoechst-propidium iodide staining. Intracellular reactive oxygen species (ROS) production was measured using the fluorescent probe 2'-7'-dichlorofluorescin diacetate and flow cytometry. The protective role of eicosane on NMDA-induced RGC injury in a mouse glaucoma model was determined by immunostaining of frozen sections of retina. The effects of eicosane on the metabolome of the retina in mice with NMDA-induced RGC damage were evaluated by liquid chromatography-mass spectroscopy (LC-MS) and untargeted metabolomics analyses.
RESULTS: Eicosane treatment significantly attenuated glutamate-induced damage to R28 cells in vitro. Eicosane also protected RGCs against NMDA-induced injury in a mouse glaucoma model. Untargeted metabolomics analyses showed that eicosane increased multiple metabolites, including L-arginine and L-carnitine, in the retina.
CONCLUSION: Eicosane has protective effects, antioxidant potential, and anti-inflammatory properties in an in vitro model of glutamate-induced cell damage and in an in vivo model of NMDA-induced RGC injury in mouse glaucoma through modulation of L-arginine and/or L-carnitine metabolism.