bluuebunny/crossref_metadata_2025 huggingface dataset:
EMPATHY DAN DESIGN THINKING DALAM INOVASI MANAJEMEN PENDIDIKAN ISLAM DI ERA DISRUPTIF
Authors: Afina Mauliya  , Suci Wulandari
Published: April 2021

Abstract

the phenomenon of the current disruptive era makes technology develop fast paced. The rapid progress must be matched with the ability of human resources as the executor of the organization. This study aimed to find out the management innovation in Islamic education institution that nowadays becomes a serious concern to face the global competition. The abilities of empathy and design thinking are the skills that need to be had by headmasters in facing the disruptive era. Innovation in Islamic education management is essential to do considering that the success of education goals is seen from how to manage an organization. This study is the result of literary research sourced from indexed scientific journals, books, and news on the internet. The procedures used included three phases, namely organize, synthesize, and identify.  The result of content analysis showed the concept of design thinking as the process to obtain problem solving which is relevant to the education field namely the formulation of new policy and analysis towards a problem by collecting analyses so that it is helpful to obtain right and effective decision making.

Abstrak

Fenomena era disruptif saat ini menjadikan teknologi berkembang serba cepat. pesatnya kemajuan harus diimbangi dengan kemampuan SDM sebagai pelaksana organisasi. Penelitian ini bertujuan untuk menggali inovasi manajemen di lembaga pendidikan Islam yang saat ini menjadi perhatian serius untuk menghadapi persaingan global. Kemampuan empati dan design thinking adalah skill yang harus miliki oleh kepala sekolah dalam menghadapi era disruptif. Inovasi dalam manajemen pendidikan Islam penting dilakukan mengingat keberhasilan tujuan pendidikan dilihat dari cara mengelola organisasi. Penelitian ini merupakan hasil riset kepustakaan dengan referensi jurnal ilmiah terindeks, buku dan berita di internet. Prosedur yang digunakan meliputi 3 tahap, yaitu organize, synthesize dan identify.  Hasil analisis isi menunjukkan konsep design thinking sebagai proses menghasilkan problem solving relevan dalam dunia pendidikan khususnya perumusan kebijakan baru dan analisis terhadap suatu permasalahan dengan mengumpulkan analisa-analisa sehingga membantu dalam upaya pengambilan keputusan yang tepat dan efektif.
PROBLEMATIKA PEMBELAJARAN ANAK USIA DINI DI MASA COVID-19
Authors: Wahab Gusnarib , Kahar M. Iksan
Published: April 2021

Pendidikan yang semula dengan metode tatap muka di lembaga pendidikan, kini diubah menjadi pembelajaran daring/online dan dilaksanakan dari rumah masing-masing untuk mencegah dan menanggulangi penyebaran virus COVID-19 ini. Kebijakan tersebut berlaku bagi semua jenjang pendidikan baik dari tingkat PAUD hingga tingkat perguruan tinggi. Hal tersebut menimbulkan banyak problematika khususnya pelaksanaan pembelajaran bagi anak usia dini. Pembelajaran dengan menggunakan sistem daring ataupun sistem online ini masih mengalami banyak problematika dalam penerapannya, karena anak tidak dapat belajar sendiri tanpa pendampingan dari orang tua. Dalam mendorong kualitas pembelajaran pada Anak Usia Dini perlu kerjasama dan dukungan  orang tua. Orang tua menjadi salah satu pihak yang bertanggung jawab dalam keberlangsungan pendidikan anak usia dini di masa covid-19. Pengasuhan positif, penyediaan lingkungan belajar yang memadai, dan sumber belajar yang relevan akan sangat membantu anak usia dini dalam menjalani masa transisi menuju era new normal. Oleh karena itu, komunikasi antara guru dan orang tua harus berjalan dengan baik. Kebijakan pemerintah tentang belajar dari rumah tidak serta merta membuat guru melepaskan tugasnya dalam memberikan pendidikan kepada anak usia dini. Justru hal tersebut menuntut guru untuk meningkatkan kompetensinya dalam melakukan pembelajaran jarak jauh dan tetap menilai perkembangan anak berdasarkan laporan kegiatan dari para orang tua.
Impact of packing density on primary drying rate
Authors: Matejčíková Anna , Rajniak Pavol
Published: April 2021

This work aimed to determine the effect of packing density on the sublimation rate in a laboratory freeze dryer. Total amount of sublimed water was determined by gravimetric method while a total of seven experiments were performed under the same conditions (pressure, temperature, and drying time), at different configuration of the vials. The experiments confirmed that the higher the packing density, the lower the drying rate, and vice versa, the lower the packing density, the higher the drying rate. The effect of vials packing density was confirmed by experiments using a plastic rack, while the vials were separated and thus the packing density was lower. In this case, the drying rate was more homogeneous, which contributes to the higher quality of the final product.
Expression of Platelet Derived Growth Factor a, Its Receptor, and Integrin Subunit Alpha V in Feline Injection-Site Sarcomas
Authors: Ahmed Ishtiaq , Mahmut Sozmen
Published: April 2021

Injection-site sarcomas are considered an important entity in veterinary oncology, especially in cats. The current study investigated the immunohistochemical expression of platelet-derived growth factor A (PDGFA), platelet-derived growth factor receptor-α (PDGFR-α), and integrin alpha subunit v in feline injection-site sarcomas (FISS). A total of 14 paraffin-embedded tissue samples previously diagnosed as soft tissue sarcomas were selected from the departmental archive and sectioned at 5µm using a microtome. Tissue sections were stained with Hematoxylin & Eosin, Alcian blue-Periodic Acid Schiff (AB-PAS), Masson’s Trichrome, and immunohistochemically for PDGFA, PDGR-α, and integrin alpha v. The majority of the tumors were fibrosarcomas (n=13/14), except one case of myxoid liposarcoma. The tumors occurred at sites commonly used for injections or vaccine administration. Histologically, tumors were characterized by peripheral infiltration of mononuclear cells mainly lymphocytes, variable sized central necrotic areas, and many multinucleated tumor giant cells. AB-PAS staining revealed the presence of myxoid or mucinous areas in (8/14) tumors while trichrome staining demonstrated a variable amount of collagenous stroma in 12/14 tumors. Vimentin immunoreactivity was observed in all the tumors while smooth muscle actin and muscle actin staining was noticed in four and two cases, respectively. PDGFA and PDGFR-α immunoexpression was observed in all 14 cases while integrin alpha v in 13/14 cases. The results of the current study indicate that fibrosarcoma is the major morphologic phenotype of FISS. The PDGFA, its receptor, and integrin alpha v immunoexpression are increased in these tumors in cats which elucidates their role in the pathogenesis of FISS.
Genetic Analysis and Distribution of Porcine Parvoviruses Detected in the Organs of Wild Boars in Serbia
Authors: Jakov Nišavić , Nenad Milić , Andrea Radalj , Dejan Krnjaić , Dragan Milićević , Aleksandra Knežević , Marina Radojičić , Sonja Obrenović , Milivoje Ćosić , Bojana Tešović , Damir Benković , Aleksandar Živulj
Published: April 2021

Porcine parvoviruses (PPVs) are diverse and persistently evolving viruses found in domestic pigs and wild boars. Porcine parvovirus 1 (PPV1) causes reproductive problems in adult animals, although the veterinary relevance of PPV2, PPV3, and PPV4 has not been clarified. The detection and sequence analysis of PPVs circulating in wild boar populations in Serbia was performed to determine their phylogenetic relationships and prevalence in 122 organ samples collected during 2018. The DNA of PPV1, PPV2, and PPV3 was detected in 56.6% of the examined samples, whilst PPV4 was not identified. Overall, PPV3 was the most prevalent in 69.6% of the positive samples, followed by PPV1 in 63.8%, and PPV2 in 21.7% samples. Single infections were more common, although concurrent infections were confirmed in 34.8% samples for two, and 10.1% samples for three viruses. Sequence analysis of wild boar PPV1 showed no significant nucleotide differences from domestic pig PPV1 strains detected in Europe and the USA, however separate clustering from strains from China and the NADL-2 strain was demonstrated. Examination of the selected PPV2 sequences might suggest a certain geographical distribution of genetically diverse PPV2 strains considering high similarities to the strains from neighboring countries, and variability in comparison with other reported PPV2 sequences from different parts of the world. Wild boar PPV3 sequences clustered separately from most of the strains detected in wild boars, as well as the original porcine hokovirus strain. It is further noted that genetically different PPV3 strains circulate amongst Serbian domestic pigs and wild boars.
Rapid Identification for Serotyping of African Swine Fever Virus Based on the Short Fragment of the EP402R Gene Encoding for CD2-Like Protein
Authors: Thanh Tran Ha Thi , Duc Truong Anh , Viet Ly Duc , Van Hoang Tuan , Thi Nguyen Chinh , Thi Chu Nhu , Thi Nguyen Huyen , Vu Dang Hoang
Published: April 2021

The first confirmed case of African swine fever (ASF) in Vietnam was officially reported in February 2019. To date, the ASF virus (ASFV) has been detected in all 63 cities/provinces in Vietnam. In order to get a better understanding of the potential role of the EP402R gene in a grouping of ASFV serotypes, thirty ASFV sequences of EP402R genes (accession numbers: MN711757-86) from North Central Coast of Vietnam and 68 well-known references of serotype groups from previous studies were further analyzed. Interestingly, we found that a short fragment of 90 nucleotides was very typical for 8 serological groups of ASFVs. A primer set was designed to amplicon the short fragment of 90 nucleotides using the Primer3 program to establish a simplified method for the serotyping of ASFV. Our results indicated that phylogenetic analysis of the short fragment (90 nucleotides) of the EP402R gene is a very specific and useful method for ASFV serotyping when compared to the previous method using a long fragment (816 nucleotides) of this gene and well-known serotype references based on haemadsorption inhibition (HAI) assay.
First Confirmed Clinical Case of Anaplasma platys in a Dog in Serbia
Authors: Anja Ilić Božović , Milena Radaković , Kristina Spariosu , Phyllis Tyrrell , Ramaswamy Chandrashekar , Dušan Mišić , Milica Kovačević Filipović
Published: April 2021

In September 2018, a four-month-old dog with fever and petechial bleeding came to the internal clinic at the Faculty of Veterinary Medicine University of Belgrade. On hematology analysis, thrombocytopenia and mild anemia were observed. Examination of the blood smear revealed platelet inclusions. The commercial serology test was positive for Anaplasma spp. The dog was treated with doxycycline for 14 days, and after 48 hours from the beginning of the treatment, the symptoms subsided. PCR analysis and sequencing confirmed infection with A. platys.
The Antioxidant Analysis of Selected Types of Climbing Plants with Therapeutic Effect
Authors: Hrúzová M. , Mňahončáková E. , Šimková J.
Published: April 2021

Climbing plants with therapeutic effects are relatively little studied group of medicinal species. In the collection of climbing species planted in 2019 in the Botanical Garden of the Slovak University of Agriculture (SUA) in Nitra, we observed the growth and potential food, horticulture and healing use. For the antioxidant analysis, 7 species from 152 plants of 13 genera and 22 species were selected. The highest antiradical activity was recorded in the species Vigna sinensis, where reached average measured values achieved up to 73.79%. However, the related species Vigna unguiculata achieved only 26% of antioxidant activity. Of the fruits, the highest activity was Momordica charantia in immature state (73%). Other fruits showed very low antiradical activity
Light Two-Wheeled Electric Vehicle Energy Balance Investigation Using Chassis Dynamometer
Authors: Racewicz Szymon , Kazimierczuk Paweł
Published: April 2021

The article presents the methodology for light two-wheeled electric vehicle energy balance investigation using MAHA LPS 3000 chassis dynamometer. For this purpose, the laboratory tests, as well as the road tests, have been performed on the self-constructed light two-wheeled electric vehicle equipped with the 3 kW BLDC motor and the 100.8 V battery pack. The road test data have been used to set up the dynamometer parameters in order to simulate the real road drive taking into account, among others, the rolling resistances and the air drag coefficient. The overall energy consumption for the laboratory tests and the road conditions’ tests have been then compared for different vehicle speeds. In addition, based on the power and the torque characteristics measured on the MAHA chassis dynamometer, the efficiency of the vehicle electric drive system and the efficiency of the battery charging process have been calculated.
Technical, Biological and Molecular Aspects of Somatic Cell Nuclear Transfer – A Review
Authors: Mrowiec Patrycja , Bugno-Poniewierska Monika
Published: April 2021

Since the announcement of the birth of the first cloned mammal in 1997, Dolly the sheep, 24 animal species including laboratory, farm, and wild animals have been cloned. The technique for somatic cloning involves transfer of the donor nucleus of a somatic cell into an enucleated oocyte at the metaphase II (MII) stage for the generation of a new individual, genetically identical to the somatic cell donor. There is increasing interest in animal cloning for different purposes such as rescue of endangered animals, replication of superior farm animals, production of genetically engineered animals, creation of biomedical models, and basic research. However, the efficiency of cloning remains relatively low. High abortion, embryonic, and fetal mortality rates are frequently observed. Moreover, aberrant developmental patterns during or after birth are reported. Researchers attribute these abnormal phenotypes mainly to incomplete nuclear remodeling, resulting in incomplete reprogramming. Nevertheless, multiple factors influence the success of each step of the somatic cloning process. Various strategies have been used to improve the efficiency of nuclear transfer and most of the phenotypically normal born clones can survive, grow, and reproduce. This paper will present some technical, biological, and molecular aspects of somatic cloning, along with remarkable achievements and current improvements.
The Importance of Brownfield Regeneration and Improvement
Authors: Romanovska-Grīnberga Kristiāna , Ulme Andra
Published: April 2021

this research aims to explore the historical development, current situation, weaknesses and strengths of brownfield revitalization, as well as threats and possible solutions. Current situation in legislation and real life has been viewed, successful solutions globally and particularly in Latvia have been explored, innovation ideas, problems and recommendations for the improvement of the situations have been researched.
Effect of Water pH on Domestic Machine Washing Performance of Delicate Textiles
Authors: Çakmakçı Nilüfer , Candan Cevza , Arslan Başak İlkiz
Published: April 2021

In order to investigate the effect of washing water pH on textile damage for delicate garments, the study was conducted such that a customer survey was first applied to randomly selected users to analyze domestic washing machine using habits of Turkish consumers. Based on the findings of the survey, the experimental study was designed in two successive phases to investigate the dimensional and mechanical behavior of certain types of delicate textiles against varying washing conditions by taking in particular, water properties, namely pH, hardness, and temperature into account, and accordingly to determine the optimized washing conditions for such textiles. Firstly, tergotometer was employed as a washing machine simulator. Within the light of the results obtained, the experimental work of the second phase of the study was conducted, which involved a domestic washing machine as a real-life scenario. All of the results, including the correlation between the data sets obtained from the tergotometer and domestic washing machine trials, were statistically analyzed using Minitab 17. The study produced some important findings regarding the effect of washing water pH on delicate textiles, in addition to an algorithm for improving the present washing program, minimizing textile damage for mainly wool and silk garments.
Some variants of Ćirić’s multi-valued contraction principle
Authors: Alecsa Cristian Daniel , Petruşel Adrian
Published: April 2021

In this article, a study of the fixed point problem for Ćirić type multi-valued operators is presented. More precisely, some variants ofĆirić’s contraction principle for multi-valued operators, as well as a strict fixed point principle forĆirić type multi-valued will be given.
Correlation between clinical tests for gait and stability using biomechanical variables in the gait of institutionalized elderly subjects
Authors: Palma Felipe H. , Rodríguez Sebastián Cisternas , Buton Francisco Vargas , Nieva Marcela Olmos , Redenz Günther , Guzmán-Venegas Rodrigo
Published: April 2021

Study aim: This study aims to identify biomechanical gait variables explaining clinical test results in institutionalized elderly people.

Material and methods: Twenty-nine elderly (82.0 ± 6.3 years) residents in a nursing home were assessed. They were able to walk 10 meters without walking aids. First, the spontaneous gait was assessed using inertial measurement units in a 10-meter long corridor. Fifteen biomechanical gait variables were analyzed. Then, three clinical tests usually used in elderly subjects were applied: the Timed Up and Go (TUG) test, the Tinetti Scale and the Sit to Stand (STS) test. A correlation matrix using Pearson’s correlation coefficient between clinical and biomechanical variables was performed, obtaining a total of 45 potential correlations. A stepwise multiple linear regression analysis was then performed to determine the influence of each variable.

Results: TUG, Tinetti and STS were significantly correlated with similar biomechanical variables, including temporal, temporo-spatial and kinematic variables. Adults over 80 years old and women showed stronger correlations. Single support and ankle angle at takeoff were the two most important variables in stepwise regression analysis.

Conclusions: In institutionalized elderly subjects, clinical variables for gait and postural stability are correlated with the biomechanical gait variables, especially in women and adults aged over 80 years.
Law as a Language, Law as an Art: Reflections on James Boyd White's Keep Law Alive
Authors: Jefferson Powell H.
Published: April 2021

Keep Law Alive, the latest book by law and literature scholar James Boyd White, is an important apologia for the traditional understanding and practice of law in the United States. Law, White argues, has served as a language in a sense closely parallel to what we mean by referring to English or Spanish as a language: law provides those fluent in it with the tools to describe the social world and to imagine its transformation, but without scripting what the speaker must say. White also envisions law as an art that evokes imagination, emotion and personal judgment, as well as the mind, and that is fundamentally oriented toward the realization of justice. Intellectual, social and political changes, however, threaten to displace law as a language and art with a view of law as an essentially empty rhetoric that cloaks the use of abstract and impersonal reasoning often borrowed from other disciplines. The survival of law depends on the willingness of those who speak it to continue its practice as an art that serves a humane vision of political life.
The Principle of the Separation of Powers: the Ontological Presumption of an Ideologeme
Authors: Mesonis Gediminas
Published: April 2021

The theoretical materiality of the principle of the separation of powers is beyond doubt. This principle is inevitable in discourse on the constitutional framework of the state, democracy and the rule of law, and it has its own form of expression in positive law. Although the relevance of the principle of the separation of powers in social discourse creates the illusion of the conceivability of its content, the ontological questions concerning this principle remain largely vague. This can be explained by considering two aspects. First, as established in scientific doctrines and constitutional forms of expression, the principle of the separation of powers has become a social and legal ideologeme; it approximates an axiom which is no longer substantiated anew. Second, discourse concerning ontology is always complicated, since it calls to question the essence itself. It is complicated not only because it requires a particular intellectual effort and academic courage, but also because the outcome of such discourse is unpredictable and can lead either to the ideologeme being confirmed to be true or being unexpectedly revised, or perhaps can even lead to the demise of what has so far been self-evident, unquestionable, obvious, universally known, etc. This article analyses the ontological essence of the principle of the separation of powers – an approach towards the human being, whereby meaning is given to the consequent system of causal relationships within the whole theory. Discourse in this article takes ontological issues as its object of inquiry: why did we decide to separate powers and how many of these separated powers are there?
Modeling the Patterns of Civil Confiscation: Balancing Effectiveness, Proportionality and the Right to Be Presumed Innocent
Authors: Bikelis Skirmantas
Published: April 2021

This article elaborates on recent developments in modelling the advanced measure for prevention of organized and serious criminality and corruption – civil confiscation. It distinguishes and discusses the safeguards in civil confiscation patterns that are supposed to ensure the balance between the effectiveness and proportionality of the recovery of the proceeds of crime. Based on different sets of the distinguished safeguards, the article abstracts the variety of civil confiscation patterns in European national jurisdictions into three models and discusses the advantages and the risks the regulation based on these models may pose. The analysis is supplemented with the assessments made by the European Court of Human Rights in the cases related to civil confiscation regulation and insights of the practitioners who participated in the legislative proceedings on the draft of the Lithuanian law on civil confiscation. The article concludes with the thesis that some patterns of the civil confiscation may pose serious risks of disproportional or erroneous decisions to recover property and abuse of civil confiscation proceedings.
Case report of a successful pregnancy in a cystic fibrosis patient with the c.1521_1523delCTT/c.3718-2477C>t genotypes
Authors: Spasova VL , Koleva LI , Toncheva DI , Karamisheva VI
Published: April 2021

The aim of this case report was to show the consequences of pregnancy in a cystic fibrosis (CF) patient with a rare mutation. We present a case of a patient with CF, pregnant for the second time, who gave birth to a healthy child. Her mutation status revealed the presence of relatively rare mutation c.3718-2477C>T that is associated with a milder phenotype of the disease. During pregnancy, her vital signs were within normal limits. She had no exacerbations after the third gestational month. Cystic fibrosis is the most common genetic disorder among Caucasians. Over the last few decades, the survival rate and the lifespan of patients with CF have increased progressively. This is why more affected women are choosing to become pregnant. Predictive factors for the pregnancy outcome are basal pulmonary function [measured by forced expiratory volume/1 second (FEV1)], nutritional status [measured by body mass index (BMI)], diabetes and bacterial colonization. The report of our case emphasizes the need for establishing the exact mutations in CF patients who plan to become pregnant in order to predict the possible outcomes of this specific period of life. Moreover, genetic counseling is strongly recommended for the right understanding of the pregnancy risks in such cases.
Osteopetrorickets in an infant with coexistent congenital cytomegalovirus infection
Authors: Katsafiloudi M , Gombakis N , Hatzipantelis E , Tragiannidis A
Published: April 2021

Osteopetrosis refers to a group of rare hereditary disorders characterized by generalized skeletal densification due to limited bone resorption by osteoclasts. The infantile autosomal recessive form represents the most malignant one with onset early in infancy and life expectancy less than 1-2 years without therapy. Frequently, osteopetrosis is complicated by rickets, a condition called osteopetrorickets. Currently, bone marrow transplantation remains the only treatment option. We present a case of infantile autosomal recessive osteopetrosis complicated by rickets in a 2 and a half-month-old female infant with coexistent congenital cytomegalovirus (CMV) infection, successfully treated by hematopoietic stem cell transplantation (HSCT). Diagnostic procedure and differential diagnosis are discussed along with a short review of the literature. Diagnosis of osteopetrosis requires high clinical suspicion, which is enhanced by radiology and confirmed by bone biopsy and molecular analysis. Our patient has been successfully treated by HSCT and has remained in a good general condition thereafter.
Array-comparative genomic hybridization results in clinically affected cases with apparently balanced chromosomal rearrangements
Authors: Satkin NB , Karaman B , Ergin S , Kayserili H , Kalelioglu IH , Has R , Yuksel A , Basaran S
Published: April 2021

Carriers of apparently balanced chromosomal rearrangements (ABCRs) have a 2-3-fold higher risk of carrying an abnormal phenotype, when compared to the average population. Apparently balanced chromosomal rearrangements can be imbalanced at the submicroscopic level, and changes in the gene structure, formation of a new chimeric gene, gain or loss of function of the genes and altered imprinting pattern may also affect the phenotype. Chromosomal microarray (CMA) is an efficient tool to detect submicroscopic imbalances at the breakpoints as well as in the whole genome. We aimed to determine the effectiveness of array-comparative genomic hybridization (aCGH) application in phenotypically affected cases with ABCRs at a single center from Turkey. Thirty-four affected cases (13 prenatal, 21 postnatal) carrying ABCRs were investigated with CMA. In postnatal series, ABCRs were familial in 7 and de novo in 14 cases. Seven de novo cases were imbalanced (in postnatal series 33.3% and in de novo cases 50.0%). Out of 13 prenatal cases, five were familial and eight were de novo in origin and two de novo cases were imbalanced (in 15.4% prenatal series and in 25.0% de novo cases). No cryptic imbalance was observed in familial cases. The anomaly rates with array studies ranged between 14.3-25.0% in familial and between 20.0-57.5% in de novo cases of postnatal series in the literature. Studies focused on prenatal ABCR cases with abnormal ultrasound findings are limited and no submicroscopic imbalance was reported in the cohorts. When de novo postnatal or prenatal results were combined, the percentage of abnormalities detected by CMA was 40.9%. Taking this contribution into consideration, all ABCRs should be investigated by CMA even if the fetal ultrasound findings are normal.
The utility of whole exome sequencing in diagnosing pediatric neurological disorders
Authors: Muthaffar OY
Published: April 2021

Pediatric neurological disorders have a wide spectrum of clinical presentations and can be challenging to diagnose. Whole exome sequencing (WES) is increasingly becoming an integral diagnostic tool in medicine. It is cost-effective and has high diagnostic yield, especially in consanguineous populations. This study aims to review WES results and its value in diagnosing neurological disorders. A retrospective chart review was performed for WES results between the period of January 2018 to November 2019. Whole exome sequencing was requested for children with unexplained neurological signs and symptoms such as epilepsy, developmental delay, visual impairment, spasticity, hypotonia and magnetic resonance imaging (MRI) brain changes. It was conducted for children in a pediatric neurology clinic of a tertiary center at Jeddah, Saudi Arabia. Twenty-six children with undiagnosed neurological conditions were identified and underwent WES diagnosis. Nineteen patients (73.0%) of the cohort were diagnosed with pathogenic variants, likely pathogenic variants or variants of unknown significance (VUS). Consanguinity was positive in 18 families of the cohort (69.0%). Seven patients showed homozygous mutations. Five patients had heterozygous mutations. There were six patients with VUS and six patients had negative WES results. Whole exome sequencing showed a high diagnostic rate in this group of children with variable neurological disorders.
Tripolye Culture Chronology in Volhynia. Remarks Based on Materials from Ostrog-Zeman and Mezhyrich-Mistechko
Authors: Pozikhovskyi Oleksandr , Karski Kamil
Published: April 2021

Authors present results of analysis of the collection of pottery from pit no. 4 in Mezhyrich-Mistechko and pit no. 4 in Ostrog-Zeman. Both sites are located in the middle Horyn basin. The analyzed complexes are important due to the fact the relative chronology of the Malice culture and Lublin-Volhynia culture within western Volhynia and their possible connections with later communities represented by the Funnel Beaker culture and especially the Tripolye culture.
Pottery of the Funnel Beaker Culture in Settlement Contexts of the North-Eastern Coast of the Vistula Lagoon: Case Studies of Ushakovo and Pribrezhnoye Sites
Authors: Zaltsman Edwin
Published: April 2021

The article characterises new materials obtained in the course of studies of Neolithic (according to the Baltic periodisation) settlements of the Vistula Lagoon coast. These sources according to all their features belong to the Funnel Beaker culture, whose monuments were previously unknown in the region. All Funnel Beaker materials were identified in settlements, the main cultural complexes of which belong to the Primorskaya culture. Small sites of the Funnel Beaker culture existed here before the arrival of the Primorskaya population. In Ushakovo 3, Funnel Beaker pottery were found in the cultural layer in the eastern part of the excavation area, where it lies mainly separate from ceramics of the Primorskaya culture. In Pribrezhnoye, in addition to pottery, traces of two constructions with a double-row pillar wall structure were found. Buildings were of a ground type, elongated, with a width of not more than 3.20 m. Technological and morphological characteristics of ceramic fragments found within the buildings leave no doubt that these complexes belong to the Funnel Beaker culture. Also, two amphorae with typical features of the ‘badenised’ Funnel Beaker culture were revealed here. Funnel Beaker ceramic ware was also found in the cultural layer of settlements. All these materials from the settlements of Ushakovo 3 and Pribrezhnoye are dated in the range of 3500-3100 BC. It is most likely that inconsiderable human groups of the Funnel Beaker culture reached the coastal area around the middle of the 4th millennium BC when local communities of the Neolithic Zedmar culture had existed on this territory for a long time.
A Spatial Pattern(S) of the Eneolithic Multi-Phase Settlement of Brînzeni IV (North-Western Moldova) from the Perspective of Non-Invasive Geophysical Surveys
Authors: Sîrbu Ghenadie , Król Dariusz , Przybyła Marcin M. , Rybicka Małgorzata
Published: April 2021

Non-invasive geophysical methods are often very useful and efficient in the investigation of various archaeological sites. Using one of the most popular of them, i.e. magnetometry, we carried out a survey of the area of the multi-phase Eneolithic site of Brînzeni IV (north-western Moldova) in 2019. As a result, the spatial arrangement of the site and its current state of preservation were preliminarily identified.
Technical Problems in the Renovation of Historic Bridges. Case Study – Road Bridge in Cigacice
Authors: Mielczarek Magdalena , Nowogońska Beata
Published: April 2021

The road bridge in Cigacice is a very good example of and testimony to the level of knowledge and skills in interwar engineering art. The bridge is almost 100 years old, put to use in 1925, and was designed and manufactured by Beuchelt & Co. in Zielona Góra. The bridge has 10 spans with a parabolic main span, and the supporting structure for the spans is made of steel lattice girders. The object has been strengthened and modernized several times. Currently, renovation works are also being carried out, resulting from identified unfavorable corrosion of the steel elements of the bridge and the concrete bridge slab. The historic steel structure and the bridge supports are being renovated according to the conservation recommendations.
Analytical Models for Optimal Design of a Trapezoidal Composite Channel Cross-Section
Authors: Pourbakhshian Somayyeh , Pouraminian Majid
Published: April 2021

In this paper, several analytical models are presented for the optimal design of a trapezoidal composite channel cross-section. The objective function is the cost function per unit length of the channel, which includes the excavation and lining costs. To define the system, design variables including channel depth, channel width, side slopes, freeboard, and roughness coefficients were used. The constraints include Manning’s equation, flow velocity, Froude number, and water surface width. The Simultaneous Perturbation Stochastic Approximation (SPSA) algorithm was used to solve the optimization problem. The results are presented in three parts; in the first part, the optimal values of the design variables and the objective function are presented in different discharges. In the second part, the relationship between cost and design variables in different discharges is presented in the form of conceptual and analytical models and mathematical functions. Finally, in the third part, the changes in the design variables and cost function are presented as a graph based on the discharge variations. Results indicate that the cost increases with increasing water depth, left side slope, equivalent roughness coefficient, and freeboard.
Theoretical and experimental aspects of the controlled movement of solenoid actuators by means of the voltage static converter with logic gates
Authors: Kesucz Flaviu-Nicolae
Published: April 2021

The purpose of the scientific research in this paper is to control the movement of electromechanical actuators, through a new voltage convertor. The optimization of the system consists in finding new solutions to control the movement of electromechanical actuators in the gas valve, used in thermal power plants, which can be operated by static converters - with logic gates.
Exploring Relations between Heritage Interpretation, Visitors Learning Experience and Tourist Satisfaction
Authors: Moreno-Melgarejo Alberto , García-Valenzuela Luis Javier , Hilliard Ivan , Pinto-Tortosa Antonio Jesús
Published: April 2021

The main objective of the heritage interpretation is communication and dissemination of scientific knowledge generated around a certain site. Therefore, this article aims to demonstrate that the use of an adequate interpretation methodology contributes to improving a mere aesthetic experience through greater learning outcomes, more intense emotional binding, higher awareness of the heritage conservation and overall satisfaction with the visit. Thus, the heritage interpretation has become a critical tool for creating competitive cultural or nature-based tourism services and products providing hosting destinations with attractive tourism offers. The methods of this study include a literature review, which summarises the findings of different research projects assessing the relationship between the aforementioned variables. The main conclusions drawn from this review are that there exist adequate methodologies for the heritage interpretation, which contribute to improve learning outcomes, improved tourist satisfaction and emotional experiences during the visit.
Potentials of Agrotourism on Social and Economic Development of the Selected Agricultural Farms and Adjoining Communities in South-Western Nigeria
Authors: Oladeji Sunday Oladipo , Ariyo Olukayode Temitope , Alabi Opeyemi Iyinoluwa
Published: April 2021

Agrotourism industry has contributed immensely to economy of many developing nations, especially in Asia and Sub-Saharan Africa. This forms a basis for these research findings aimed at assessing the potential of agrotourism in Obasanjo Farm and Oakfield farm for improving the livelihood of immediate communities. This study employed a multiple research instrument while theoretical and specific practical approaches were used in the identification and classification of the potential agrotourism activities using a thematic qualitative, descriptive quantitative and SWOT analysis. The results show that 71% of the respondents have basic knowledge of agrotourism. The Likert scale shows that the respondents completely agreed (4.52) that agrotourism is beneficial to people and equally agreed (4.56) on the need to develop it. Recommendations are drawn from the SWOT analysis on the need for farm management to strengthen available opportunities through incorporating agrotourism activities with other farming activities, while addressing the environmental threats and organisational weaknesses.
White space interpretation in Hermann Rorschach’s inkblot test: An analysis of two male examinees’ responses
Authors: Hunca-Bednarska Anna
Published: April 2021

Introduction: There are numerous points of controversy over the psychological interpretation of the so-called S responses – namely, the interpretation of white space in the Rorschach test. The aim of my paper was to verify the position held by Charles P. Fonda, who claims that the meaning of S responses depends on the results of the test as a whole.

Materials and methods: I have presented the responses of two young men and coded them according to the Comprehensive System developed by John E. Exner. I chose this way of processing data as the most precise, relatively well formalized, and detailed one. The two examinees gave an almost identical number of responses in the whole test and a similar number of S responses, similarly distributed across the cards of the test.

Results: I assessed and compared the results of the two examinees in terms of the effectiveness of their cognitive processes, self-control ability, mental resources, social adjustment, and self-esteem. Finally, I looked closely at the contents of a few responses, as in my opinion they symbolically expressed the examinees’ basic problems.

Discussion: I tried to avoid describing the examinees’ psyche in nosological terms and to focus on presenting the way in which they experienced the world, as well as on how this experience affected their behavior.

Conclusions: I found that in Examinee 1 criticism towards other people may stem from an excessively idealistic attitude to the world and from the ensuing disappointments. Good cognitive functioning, resistance to stress, positive self-esteem, and the socialized emotional sphere make this man’s S responses a sign of creative engagement in the problems encountered rather than a sign of maladjustment. In the case of Examinee 2, S responses can be understood as defiance and a generalized attitude of negativism, which play the role of defense against the excessively complicated, not fully comprehensible, and inhospitable world; these responses may, in their turn, contribute to the intensification of problems and to an increase in maladjustment.
The population of Crataegus ucrainica (Rosaceae) in the Valley of the River Svydnya, Eastern Ukraine (Desna basin)
Authors: Shevchyk Oksana V. , Dvirna Tetyana S. , Solomakha Volodymyr A. , Postoenko Volodymyr O.
Published: April 2021

A new locality for Crataegus ucrainica in the ravine-valley system of the River Svydnya valley (Desna basin) near the town of Krolevecz (Sumy region) has been reported. This article presents the results of a study of C. ucrainica within the species’ distribution. Based on a survey of the identified population, its ecological and coenotic features, and the ontogenetic state of the population are presented. The species is confined to areas with steep slopes, which are inaccessible for grazing, where clay deposits are exposed. The complexity of these ecotopes provides a good preservation of individuals in open meadows, forest edges, as well as in thickets of Robinia pseudoacacia and Populus alba. The coenotic affiliation of some individuals and thickets of this species to meadow-steppe, natural forest and spontaneous tree-shrub vegetation is noted. The state of the studied population in the Desna river basin is stable and sufficient for its preservation, its existence is due to the optimal hydrological regime of the slopes, which is associated with the presence of accumulated water at the bottom of valley s and a low groundwater level. The map shows the peculiarities of the distribution of the identified populations of C. ucrainica in Ukraine. A comparison of biotopes, ecotopes, soils, and vegetation types, in which populations of C. ucrainica in the area of their distribution are presented. Analysis of the seed products of this species according to analysis from different habitats allows us to assert the existence of favourable conditions for its distribution in the presence of optimal habitats.
The impact of regional demographics on Higher Education Policy. An example from Silesia, Poland
Authors: Krzysztofik Robert , Zagórowska Agata , Kantor-Pietraga Iwona , Malchar-Michalska Dominika , Lamparska Marzena , Dudek Aleksandra
Published: April 2021

The determinants of higher education policy have their sources in various spheres, such as economic, social, educational, national policy, administrative, and demographic. Problems for the development of higher education also stem from these spheres. One of them is the challenging demographic situation that is a significant element of developing higher education in southern Poland (particuarly in the Silesia region). Given this context, this article aims to indicate the policies of the universities in the region which respond to the existing demographic threats. This relationship is to confront student opinions regarding their vision for their education and future career within the current demographic situation. Using research-based on an analysis of university and regional local government strategic documents and surveys carried out among students, we conclude that higher education development policy is responding to the demographic transformation. Meanwhile, students’ attitudes to the challenges of the demographic situation is quite “flexible” and relatively ambivalent. This article presents the contrast between the increasingly tricky demographic situation in Silesia, Poland, and the limited response in the two main groups of stakeholders – academic authorities and students – that require shaping higher education ipolicy towards future demographic challenges.
The damage caused by landslides in socio-economic spheres within the Kigezi highlands of South Western Uganda
Authors: Nseka Denis , Mugagga Frank , Opedes Hosea , Ayesiga Patience , Wasswa Hannington , Mugume Isaac , Nimusiima Alex , Nalwanga Faridah
Published: April 2021

An assessment of the socio-economic implications of landslide occurrence in the Kigezi highlands of South Western Uganda was conducted. Landslide occurrence is on the increase and threatens community livelihoods in these highlands. Detailed field investigations were undertaken with the help of local communities between June 2018 and May 2020 to identify and map recent and visible landslide scars in Rukiga uplands of Kigezi highlands. In the course of field inventories, 85 visible landslide scars were identified and mapped using handheld GPS receivers to produce a landslide distribution map for the study area. A socio-economic analysis was conducted to establish the effects of landslide damage on people’s livelihoods as well as their existing coping and adaptation mechanisms. The assessment was administered through field observations and surveying, focus group discussions, key informants and household interviews as well as the use of Local Government Environmental Reports. The study established an increase in the spatial-temporal distribution of landslides over the Kigezi highlands in the past 40 years. The landslides have resulted in a reduction in the quality of land, loss of lives, destruction of transport infrastructures, settlements, farmlands, crops and other socio-economic infrastructures. Therefore, it is important to look for reliable and sustainable measures to prevent landslide hazards. Total landscape reforestation with deep-rooted trees can possibly reduce the landslide risk. It is also important to undertake policy implementation for preparedness and mitigation plans against landslides in this region and in the country at large. Proper soil and water conservation measures could help in enhancing soil strength against landslide hazards.
Understanding Arab American Identity through Orientalist Stereotypes and Representations in Mohja Kahf’s The Girl in the Tangerine Scarf (2006)
Authors: Berrebbah Ishak
Published: April 2021

Arab-American women’s literature has emerged noticeably in the early years of the 21st century. The social and political atmosphere in post-9/11 America encouraged the growth of such literature and brought it to international attention. This diasporic literature functions as a means of discussing the Orientalist discourse that circumscribes Arab American identity and its effects in determining their position in the wider American society. As such, this article investigates the extent to which Edward Said’s discourse of Orientalism is employed by Mohja Kahf in her novel The Girl in the Tangerine Scarf (2006) to project the stereotypes and misrepresentations that confine the identity of Arab and Muslim characters in the US society. This article suggests that post-9/11 Arab American fiction serves as a literary reference to such stereotype-based discourse in the contemporary era. The arguments in this article, while employing an analytical and critical approach to the novel, are outlined within postcolonial and Orientalist theoretical frameworks based on arguments of prominent critics and scholars such as Peter Morey, Edward Said, and Jack Shaheen, to name just a few.
Genetic characterisation and population structure analysis of Anatolian figs (Ficus carica L.) by SSR markers
Authors: Ergül Ali , Büyük Burcu Pelin , Hazrati Nahid , Yılmaz Funda , Kazan Kemal , Arslan Nur , Özmen Canan Yüksel , Aydın Semra Soydam , Bakır Melike , Tan Nilgün , Kösoğlu İlknur , Çobanoğlu Ferit
Published: April 2021

The common fig (Ficus carica L.) is a tree species and is one of the oldest fruit trees cultivated in Turkey. The Western Anatolian region of Turkey produces nearly a quarter of the total dried fig production of the world. This region also harbours a rich fig germplasm. However, so far this germplasm has remained largely uncharacterised. In this study, using 14 simple sequence repeat (SSR) primer pairs, we analysed a total of 310 fig accessions from six different regions of Anatolia. In structure analyses, Western Anatolian accessions formed a group, which was correlated with their geographical distribution. In addition, 7 identical, 36 synonymous, and 22 homonymous fig accessions were identified. In multilocus lineages (MLLs) analysis a total of 54 accessions were matched to different accessions as clone assignment. The results will facilitate future germplasm management and breeding efforts in this economically important tree species by identifying genetic diversity, genetic relations and characterising the structure of studied populations and accessions.