bluuebunny/crossref_metadata_2025 huggingface dataset:
Work on sound, intonation and technique when playing the clarinet in the educational process
Authors: Жуйци П.
Published: June 2023

В рамках данной статьи автор поднимает проблематику работы над звуком, интонацией и техникой при игре на кларнете в образовательном процессе. Автор подчеркивает важность и значимость указанной темы. В ходе исследования автор приходит к выводу, что работа над звуком, интонацией и техникой при игре на кларнете является ключевой частью образовательного процесса. Для достижения высоких результатов в игре на кларнете необходимо обратить внимание на ряд важных аспектов, включая правильное дыхание, осанку игрока, артикуляцию и атаку звуков, контроль над интонацией и динамикой звучания, а также овладение техниками игры на высоких скоростях. Педагог может проводить различные упражнения и техники, которые помогут ученикам улучшить каждый из этих аспектов и достичь наилучших результатов в игре на кларнете. Для контроля над интонацией и динамикой звучания используются специальные упражнения по строю, громкости и расстановке акцентов. Педагог может обеспечить индивидуальную помощь и коррекцию каждому ученику при развитии его техники игры, а также использовать различные звуковые упражнения для улучшения качества звучания и точности игры на кларнете. Непрерывный и систематический труд в процессе обучения является ключевым фактором для достижения высоких результатов на кларнете. Регулярные занятия, участие в музыкальных мероприятиях и игра в ансамбле помогут развивать музыкальные способности учеников и обогащать их опыт в области игры на кларнете.

Within the framework of this article, the author raises the problems of working on sound, intonation and technique when playing the clarinet in the educational process. The author emphasizes the importance and significance of this topic. In the course of the research, the author comes to the conclusion that working on sound, intonation and technique when playing the clarinet is a key part of the educational process. To achieve high results in playing the clarinet, it is necessary to pay attention to a number of important aspects, including proper breathing, player posture, articulation and attack of sounds, control over intonation and dynamics of sound, as well as mastering the techniques of playing at high speeds. The teacher can conduct various exercises and techniques that will help students improve each of these aspects and achieve the best results in playing the clarinet. To control the intonation and dynamics of the sound, special exercises are used on the structure, volume and placement of accents. The teacher can provide individual assistance and correction to each student in the development of his playing technique, as well as use various sound exercises to improve the sound quality and accuracy of playing the clarinet. Continuous and systematic work in the learning process is a key factor for achieving high results on the clarinet. Regular classes, participation in musical events and playing in an ensemble will help develop the musical abilities of students and enrich their experience in the field of clarinet playing.
The specifics of teaching professional terminology in a foreign language class at a non-linguistic university
Authors: Арская М.А.
Published: June 2023

Статья посвящена вопросам обучения английской терминологии на занятиях по иностранному языку в образовательных организациях системы МВД России. Подчеркивается необходимость учета приоритетного профиля подготовки будущих полицейских. Дается обзор существующих на данный момент толковых (терминологических) словарей, содержание которых составляет лексика, объединенная в рамках т.н. наркотематики. Приводится авторская методика работы с английской терминосистемой сферы незаконного оборота наркотиков на примере центрального компонента семантического поля «наркотики» – термина «drug». Делается вывод о повышении мотивации к изучению профессиональной иноязычной лексики благодаря привлечению экстралингвистического информации.

The article is devoted to the issues of teaching English terminology in foreign language classes in educational institutions of the system of the Ministry of Internal Affairs of Russia. The necessity of taking into account the priority profile of the training of future police officers is emphasized. An overview of currently existing definition (terminological) dictionaries is given, the content of which is vocabulary, united within the framework of drug topics. The author's method of working with the English terminological system of the sphere of drug trafficking is given on the example of the central component of the semantic field "drugs" – the term "drug". It is concluded that there is an increase in motivation for the study of professional foreign vocabulary due to the involvement of extralinguistic information.
A Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu2+ in the Brain
Authors: Zhu Jianping , Graziotto Marcus E. , Cottam Veronica , Hawtrey Tom , Rouaen Jourdin R. C. , Ohno Carolyn , Heisler Marcus , Vittorio Orazio , Double Kay L. , New Elizabeth J.
Published: June 2023

Copper participates in a range of critical functions in the nervous system in the human brain. Disturbances in brain copper content is strongly associated with neurological disease. For example, changes in the level and distribution of copper are reported in neuroblastoma, Alzheimer's disease and Lewy body disorders. There is a need for more sensitive techniques to measure intracellular copper levels to have a better understanding of the role of copper homeostasis in neuronal disorders. Here we report a reaction-based near-infrared (NIR) ratiometric fluorescent probe CyCu1 for imaging Cu2+ in biological samples. High stability and selectivity of CyCu1 enabled the probe to be deployed as a sensor in a range of systems, including SH-SY5Y and neuroblastoma cells. Furthermore, it can be used in plant cells, reporting copper added to Arabidopsis roots. We also used CyCu1 to explore Cu2+ levels and distribution in postmortem brain tissues from patients with the Lewy body disorder, Dementia with Lewy bodies (DLB). We found significant decreases in Cu2+ content in the nuclei, cytoplasm, neurons and extraneuronal space in the degenerating substantia nigra (SN) in DLB compared with healthy age-matched control tissues. These findings enhance our understanding of Cu2+ dysregulation in Lewy body disorders. Our probe also shows promise as a photoacoustic imaging agent, with potential for applications in bimodal imaging.
Detecting Reactive Products in Carbon Capture Polymers with Chemical Shift Anisotropy and Machine Learning
Authors: Marple Maxwell , Li Sichi , Hunter-Sellars Elwin , Pang Simon
Published: June 2023

Aminopolymers are attractive sorbents for CO2 direct air capture applications as their amines readily react with atmospheric levels of CO2 to form chemisorbed species. The identity of the chemisorbed species varies upon experimental conditions like amine chemistry, support material, CO2 loading, and humidity, forming a variety of carbonyl-type sites. 13C solid-state nuclear magnetic resonance (NMR) is often used to help elucidate the identity of the chemisorbed species however the chemical shift range for carbonyl sites is small and comparable to observed chemisorbed 13C peak widths. Herein, application of a 2D chemical shift anisotropy (CSA) recoupling pulse sequence (ROCSA) is used to obtain CSA tensor values at each isotropic chemical shift, overcoming the isotropic peak resolution limitation. CSA tensor values describe the local chemical environment and can readily differentiate between chemisorbed products. To aid this experimental technique, we also developed a k-nearest-neighbor (KNN) classification model to distinguish chemisorbed compounds via their CSA tensor parameters. The combination of 2D CSA measurements coupled with a KNN classification model enhances the ability to accurately identify chemisorbed products especially in the case of mixtures. This methodology is demonstrated on poly(ethylenimine) in a solid-support γ-Al2O3 exposed to CO2 followed by incomplete regeneration at 100 °C and shows a mixture of strongly bound chemisorbed products, ammonium carbamate and urea.
Biallelic structural variations withinFGF12detected by long-read sequencing in epilepsy
Authors: Ohori Sachiko , Miyauchi Akihiko , Osaka Hitoshi , Lourenco Charles Marques , Arakaki Naohiro , Sengoku Toru , Ogata Kazuhiro , Honjo Rachel Sayuri , Kim Chong Ae , Mitsuhashi Satomi , Frith Martin C , Seyama Rie , Tsuchida Naomi , Uchiyama Yuri , Koshimizu Eriko , Hamanaka Kohei , Misawa Kazuharu , Miyatake Satoko , Mizuguchi Takeshi , Saito Kuniaki , Fujita Atsushi , Matsumoto Naomichi
Published: June 2023

We discovered biallelic intragenic structural variations (SVs) inFGF12by applying long-read whole genome sequencing to an exome-negative patient with developmental and epileptic encephalopathy (DEE). We also found another DEE patient carrying a biallelic (homozygous) single-nucleotide variant (SNV) inFGF12that was detected by exome sequencing.FGF12heterozygous recurrent missense variants with gain-of-function or heterozygous entire duplication ofFGF12are known causes of epilepsy, but biallelic SNVs/SVs have never been described.FGF12encodes intracellular proteins interacting with the C-terminal domain of the alpha subunit of voltage-gated sodium channels 1.2, 1.5, and 1.6, promoting excitability by delaying fast inactivation of the channels. To validate the molecular pathomechanisms of these biallelicFGF12SVs/SNV, highly sensitive gene expression analyses using lymphoblastoid cells from the patient with biallelic SVs, structural considerations, andDrosophilain vivo functional analysis of the SNV were performed, confirming loss-of-function. Our study highlights the importance of small SVs in Mendelian disorders, which may be overlooked by exome sequencing but can be detected efficiently by long-read whole genome sequencing, providing new insights into the pathomechanisms of human diseases.
Word-forming semantics of nouns in denumerative word formation
Authors: Kostryba Olha
Published: June 2023

The relevance of the study is determined by the need to take into account the principle aspect in the analysis of the the word-forming system of the modern Ukrainian language. Scientific works testify that the derivatives motivated by noun-, adjective-, and verb-forming bases, which represent the core parts of the language, are considered for the most part.

The purpose of the article is to establish the word-forming semantics of denumeratives – derived nouns grouped according to the nesting principle with vertex numerals belonging to the periphery of the forming base, find out the types of derivation and models of creation.

The analysis was carried out using the structural-semantic method in combination with the use of lexical-semantic transformations.

The onomasiological aspect involves the interaction of a simple motivational base, which is represented by adjectives, nouns, numerals, and verbs, and word-forming means; hence, thirteen word-forming meanings have been established, the carriers of which are simple substantives. The word-forming semantics of compound two- and three-base nouns, motivated by word combinations with subordinating and singly consecutive types of connection, have been determined; the number of word-forming meanings of complex formations is six. The nature of the correlation of the semantics of the formed word with the word-forming means was analyzed, particularly in syntagmatic word-forming meanings complicated by subcategorization and recategorization content, thus the types of derivation of word-forming meanings were established – mutational, modificational, and transpositional. Within each of the nineteen semantic positions of derivative substantives, one hundred and twenty-nine word-forming models were identified, presented in a descending order of their performance.

The interpretation of the noun as a part of speech block in denumerative word formation contributes to the identification of the derivational capacity of the numerals of the modern Ukrainian language, complements the achievements of the principle derivation.
Kapadokya’dan Türkiye Karayosunu Florası İçin Önemli Bir Kayıt (Sciuro-hypnum glaciale (Schimp.) Ignatov & Huttunen)
Authors: KARA Recep , TAŞPINAR Hatice , SERİN Seda
Published: June 2023

Sciuro-hypnum glaciale (Brachytheciaceae, Bryophyta) Türkiye biyoçeşitliliği açısından korunması gereken önemli bir yapraklı karayosunu türüdür. Bu tür Türkiye Florasında şimdiye kadar yalnızca Doğu Karadeniz Bölgesin’de, Ordu ilinden bilinmekteydi. Bu çalışma ile Türkiye’de nadir olarak bulunan bu taksonun Kapadokya Bölgesinden yeni bir lokalite kaydı verilerek Türkiye Florasına katkı sağlanmıştır.
Design of a Load Modulated Balanced Amplifier with a Two-Stage Control Power Amplifier
Authors: Mochumbe Sagini E. , Yang Youngoo
Published: June 2023

While an ideal Doherty power amplifier has a linear response, the load modulated balanced amplifier (LMBA) has a compressive response under ideal conditions. This inherent nonlinear characteristic is due to the lower power contribution of the single auxiliary device as the balanced amplifier transistors approach compression. This article presents an LMBA with a two-stage control signal amplifier in place of the single auxiliary device. The idea is to preserve a high and constant gain across the high- and low-power regions by tuning the two-stage gain control signal to match the balanced amplifier gain. An optimal load trajectory can be found for a high-efficiency design by appropriately terminating the second harmonic while ensuring an optimal impedance match in all devices. At the same time, by setting an optimal output power from the auxiliary device, sufficient power is provided to linearize the response of the main power amplifier beyond the output back-off power boundary. As proof of concept, a prototype is designed and implemented. The experimental measurements demonstrate a drain efficiency of 59%–64% at maximum output power and 46%–52% at 7.5 dB output back-off power over the target frequency range of 3.3–3.8 GHz.
ÂŞIK VEYSEL’İN ÂŞIK TARZI ŞİİR GELENEĞİNİ TEMSİL GÜCÜ
Authors: BARS Mehmet Emin
Published: June 2023

Ozan-baksı geleneği üzerine inşa edilen âşık tarzı şiir geleneği, Türk edebiyatının en zengin kollarından biridir. Farklı zamanlarda ve Türk boylarında çeşitli isimlerle anılan geleneğin temsilcileri, bugün Anadolu ve Azerbaycan’da “âşık” olarak adlandırılmaktadır. Bu sanatçılar çok geniş bir mekânda ve uzun bir zaman diliminde farklı kültür dairelerinde yetişmiş ve güçlü bir şiir okulu meydana getirmişlerdir. Âşık tarzı şiir geleneği zamanla çeşitli değişimler ve dönüşümler yaşamıştır. Bu değişimler ve dönüşümler geleneğin varlığını günümüze kadar sürdürmesini sağlamıştır. Bu değişimlerle birlikte yüzyıllar içerisinde âşık tarzı şiir geleneğinin kendine özgü kuralları ve icra töresi oluşmuştur. Âşıklar sanatlarını icra ederken bu geleneğe göre hareket etmişlerdir. Âşıklar gelenek temelinde benzer özellikler taşımalarına rağmen bazı nitelikleriyle birbirlerinden ayrılmaktadırlar. Âşık Veysel Şatıroğlu âşık tarzı şiir geleneğinin son dönemlerde yetişen en önemli temsilcilerinden biridir. Şöhreti tüm Anadolu’ya yayılmış, her kesim tarafından tanınmış ve hakkında çok sayıda inceleme yapılmıştır. Bu çalışmada Âşık Veysel’in âşık tarzı şiir geleneğini temsil etme gücü ele alınmıştır. Âşık Veysel’in geleneği temsil gücü; âşıkların yetişmeleri/eğitimleri, rüya motifi, mahlas alma, saz çalma, irticalen şiir söyleme, atışma yapma (bağlama), askı-muamma çözme, hikâye anlatma, gurbete çıkma, yetiştikleri muhitler, âşıklığın profesyonel bir meslek olarak görülmesi, âşıklığın bir gösterim olarak görülmesi, tekke-tasavvuf edebiyatının etkisi, geleneğin şekillendiği kültür ortamları, şiirlerin yapı ve içerik özellikleri bakımından değerlendirilmiştir. Âşık Veysel âşıklık geleneğinin bu niteliklerinden bazılarını taşımamaktadır. Bununla birlikte geleneğin birçok asli niteliğini taşıyan Âşık Veysel, XX. yüzyıl âşıklık geleneğinin en güçlü temcilerinden biridir.
Factors Influencing Young Muslim Women's Decisions in Buying Halal Skincare
Authors: Bahri Halida , Bachri Naufal , Saharuddin Saharuddin , Sutriani Sutriani , Zulkifli Zulkifli
Published: June 2023

This study aims to examine the influence of lifestyle factor, religiosity, and consumer perceptions on young Muslim women's decisions to buy halal skincare in the Kota Lhokseumawe. This study uses primary data obtained by distributing structured questionnaires to 112 respondents. The sample was selected with a purposive sampling approach. The data analysis method used is multiple linear regression with the help of SPSS Software. The results of the study indicate that lifestyle, level of religiosity, and consumer perception have positive dan significant effect on young Muslim women's decisions in buying halal skincare products in Kota Lhokseumawe. This finding has implications for the development of the concept of purchasing halal products.
System for identifying the level of mobile gaming addiction in children and adolescents
Authors: Khoziasheva A.
Published: June 2023

This research paper describes a system for identifying the level of mobile gaming addiction in children and adolescents using data collected from mobile electronic devices. The system includes a mobile application that collects usage data on mobile games and uses a neural network model based on an "autoencoder" architecture to detect addiction levels. The neural network model includes the error back propagation algorithm and was trained on parameters selected from Chen Scale (CIAS) for addiction level detection. A prototype of the mobile application was created and adequate estimates of the neural network model quality were obtained. Future work will involve validation of the system with psychologists and further improvement of the neural network model by increasing the number of observations and adjusting the architecture. The results of this study demonstrate the potential of using neural networks and mobile technology to identify and monitor mobile gaming addiction in children and adolescents, which can aid in early intervention and prevention efforts.
The Relationship between GPA and Prerequisite Courses on the Mastery of Simple Machines Concepts among Physics Education PLP Students at FKIP Untan
Authors: Irmayani Ega Sri , Djudin Tomo , Oktavianty Erwina , Tiur Haratua , Firdaus Firdaus
Published: June 2023

This study aims to determine the effect of GPA and prerequisite courses simultaneously on the mastery of simple machine concepts in PLP II students at FKIP Untan Pontianak. This correlational study involved 50 seventh-semester students of the Physics education study program at the Faculty of Teacher Training and Education (FKIP) Pontianak, Tanjungpura University. Data collection was carried out using measurement techniques, namely tests. The achievement of prerequisite courses and microteaching competence of students were taken from the academic section of the faculty. The analysis found that GPA and prerequisite courses on mastery of simple machine teaching materials were significantly related to correlation coefficients (r = 0.38, r = 0.34, p < 0.05, respectively). In addition, the multiple correlation coefficient was also significant (R = 0.38, p < 0.05). This means that the relative contribution of the predictor variables of this study to the mastery of simple machine teaching materials is 15.1%, and the remaining 84.9% is determined by other factors not examined in this study. The study showed that GPA and prerequisite courses were significantly related to student's ability in the learning process.
Responsibility Of The Tual City Government In An Effort To Protect The Copyrights Of Batik Kei Motives
Authors: Balik Agustina , Hetharie Yosia , Uktolseja Novyta
Published: June 2023

This study aims to identify and analyze the responsibilities of the Tual City government in providing legal protection in the field of intellectual property rights, especially copyright for Batik Kei motifs. This research is socio-legal research, which is a combination research method between doctrinal law research methods and empirical legal research methods. This research was conducted in Tual City, namely the Kei Batik Craftsman with the name Camelia Batik Kei. The types of data in this study are primary data and secondary data obtained through library research and interviews. Based on the results of the research, the Tual City government has an important role in providing copyright legal protection for Camelia Batik Kei's business. But in reality, although the Tual City government often displays Kei Batik motifs which incidentally elevate Kei customs and culture, from the aspect of copyright protection, the government has not given it at all. The entrepreneurs of Camelia Batik Kei are also not very aware of the importance of registering and protecting copyright laws for Kei Batik’s motives. Therefore, there is a need for socialization and cooperation with the local government of Tual City to provide copyright legal protection for Kei batik motifs.
Crenças religiosas de haitianos evangélicos no Brasil: cosmovisão articulada à migração
Authors: Marcelino Bernadete Alves de Medeiros
Published: June 2023

este artigo é parte de uma pesquisa realizada com comunidades evangélicas haitianas no Brasil durante o doutorado em Ciência da Religião. Este tem como objetivo discorrer sobre crenças religiosas de haitianos evangélicos no Brasil articuladas a uma cosmovisão sobre a migração. A metodologia adotada para a pesquisa envolveu levantamento bibliográfico, etnografia e entrevistas abertas. Como parte dos resultados obtidos foi possível constatar que as migrações haitianas fazem parte da história do Haiti e têm relação com crises políticas, econômicas e catástrofes naturais, mas que crenças religiosas permeiam esse processo. Concluímos que os haitianos possuem uma maneira específica de compreender os processos migratórios, a qual nós chamamos de cosmovisão migratória, e que esta era fomentada por crenças religiosas no grupo pesquisado.
O templo como símbolo de poder: percepções sobre o segundo templo e relações com o processo político brasileiro
Authors: Guedes Mateus Soares
Published: June 2023

o presente artigo se propõe a partir de um método qualitativo, observar e descrever como o segundo templo é construído sob aspectos sociais e religiosos que lhe permitem ser observado não somente como um símbolo religioso, mas também como símbolo de poder, concedendo aqueles que possuíam ligação com ele, posições aristocráticas. A partir dessa percepção entendemos uma relação desse símbolo com os aspectos da política brasileira atual, procurando observar como a figura do templo, por si mesma, faz com que ele esteja intrinsecamente ligado aos processos políticos brasileiros.
O USO DE ESTRATÉGIAS DE PREVENÇÃO DE LESÕES DE PELE POR PRESSÃO NA MACA RÍGIDA: REVISÃO INTEGRATIVA
Authors:   , pereira tiago albernaz
Published: June 2023

RESUMO
Introdução: Os novos protocolos e diretrizes de atendimento pré-hospitalar no mundo não recomendam a permanência da vítima de traumas no geral de permanecer mais de 30 minutos na maca rígida por decorrência de lesões de pressão. A utilização do polímero viscoelástico aplicado em macas rígidas como melhor opção em comparação com a maca rígida convencional de polietileno ou compensado naval. Objetivo: Investigar e comparar a utilização da maca rígida em comparação ao polímero viscoelástico, na prevenção de lesões por pressão, dos pacientes politraumatizados. Metodologia: Trata-se de uma revisão integrativa. A coleta de dados ocorreu nos meses de outubro a novembro do ano vigente, sendo selecionadas as publicações científicas existentes em periódicos indexados nos bancos de dados Banco de Dados em Enfermagem (BDENF); National Library of Medicine (PubMed); Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), no período dos últimos cinco anos. Resultados e Discussão: A amostra final desta pesquisa foi constituída por onze artigos, em que os dados obtidos nesta pesquisa são apresentados com base na análise de conteúdos desta temática emergindo duas categorias que são: A incidência das lesões por pressão no uso dos dispositivos rígidos na imobilização padrão; O uso do polímero viscoelástico na redução da incidência das lesões por pressão ocasionadas pela imobilização padrão como maca rígida. Considerações Finais: Constatou-se que há evidências da necessidade de compreensão por parte dos profissionais de saúde que atuam no atendimento aos pacientes politraumatizados a fim de diminuir o tempo de permanência dos pacientes em superfícies rígidas e com isso diminuir a incidência de lesões por pressão relacionada a este dispositivo médico, observa- se também o uso de novas tecnologias como o colchão viscoelástico, como um alternativa para melhorar a qualidade do tempo de permanência dos pacientes que necessitem ficar imobilizados.
Cytogenetic study on some common bone tumours
Authors: Yaseen Nahi Y .
Published: June 2023

This study aimed to detect the consistent chromosomal abnormalities of each type of common bone tumours . Thirty bone tumors specimens were processed for direct cytogenetic preparation , only (9 cases) showed success results for chromosomal preparation by banding technique , the results of cytogenetic study were 1- Osteosarcoma (4) cases revealed multiple numerical and structural changes with complex karyotype and pronounced cell to cell variation . chromosome 17 was the most frequent involved in these chromosomal alteration . Also loss or structural changes of chromosome 13 was found in (2) cases of osteosarcoma loss or gain of sex chromosome were detected in these cases , loss of Y chromosome in (2) cases ; loss of X chrosome in (1) case and gain of X chrosome in another case . 2- Osteochnodroma : reveled the simple numerical change with no structural change in one case . 3- Chondroblastoma : in this tumor structural and numerical abnormalities of chrosome 5 . 4- Chondrosarcoma : showed chromosomal aberration with multiple numerical and structural changes in chromosome (1) was of interest and monsomy 18 was reported in one case . 5- Giant cell tumors : It showed a complex changes and the range of chromosomal number was 50 – 58 with the characteristic telomeric fusion in malignant cases while simple numerical change only in benign giant cell tumor . Conclusion Cytogenetic study of both benign and malignant bone tumors have revealed abnormlities in the number and / or structures of chromosomes X, Y , 1,5,6,11 , 13,17,18 and complex chromosomal changes in malignant types of bone tumors .
Antitumor activity of L-asparaginase produced from E.coli .
Authors: Al-Rawi Khalid F.
Published: June 2023

.Extra and intra-cellular L-asparaginase were produced from E.coli, purified by ammonium sulphate precipitation, ion exchange chromatography and gel filtration chromatography and tested for their anti-tumor activities against four human tumor cell lines include MCF-7 , PC3 , A549 and Hep-G2 using MTT and (HCS) array scan. The MTT assay showed that the enzymes exhibited antiproliferative activity in different cell lines growth, PC3 cell line were more sensitive to extra and intracellular L-asparaginase as it gave a lower IC50 value (27.41±2.95 and 70.12±2.53) for extra and intracellular respectively, extracellular L-asparaginase treatment increases nuclear condensation, plasma membrane permeability, MMP attenuation and increased cytochrome C in the cystol compared to control. We suggest the extra-cellular Lasparaginase of E.coli was a therapeutic agent against human PC3 cell line.
Relationship between blood lead levels and cytogenotoxic effects in human exposed to diesel exhaust
Authors: Barakat Naida Tareq
Published: June 2023

Diesel exhaust (DE) is a mixture of hundreds organic and inorganic compounds, several of them are cytogenotoxic. This way, the aim of this study was to indicate the relationship between blood lead level and the exposure to cytogenotoxic constituents of DE. Blood samples were collected from 80 nonsmoker healthy men. Sixty of them were exposed directly to DE and the others were negative control. Exposure metrics included blood lead levels (Blls) while cytogenotoxic effects of DE were investigated by using micronucleus assay (MN), sister chromatid exchange assay (SCE) and comet assay. The results showed that the means of Blls in exposed workers to DE (47.40 – 49.50) µg/dl significantly higher (P <0.01) than mean of Blls in control gruop (15.75) µg/dl. When Blls range from 60 to 80 µg/dl , the cytogenotoxic effects were significantly higher (P <0.01) than others Blls groups. So that BLL it can be indictor to exposure to DE which have cytogenotoxic effects on human.
Integration of Distributed Generators and Shunt Capacitor Banks to Minimize Power Loss and Enhance Voltage Stability Index
Authors: Ahmed Faraz
Published: June 2023

A substantial quantity of real power loss is accounted for the distribution system due to its radial nature. Efficient and secure operation of a distribution system, it is necessary to minimize the active power loss and the system’s voltage stability index (VSI). Power loss and VSI in the distribution system can be minimized with the optimal integration of distributed genera
TÖLÖGÖN KASIMBEKOV’UN ESERLERİ ÖRNEĞİNDE KIRGIZ TÜRKÇESİNDE NE…NE… BAĞLACININ İŞLEVLERİ
Authors: SALİEV Meder
Published: June 2023

Bu çalışmada “ne…ne…” bağlacının Kırgız Türkçesinde kullanım özellikleri üzerinde durulmuştur. İncelediğimiz kaynaklarda “ne…ne…” bağlacı, Kırgız yazı dilinde yaygın olarak kullanılmamakla birlikte daha çok Kırgız Türkçesinin güney ağızlarında kullanıldığı belirtilmektedir. Kırgız Türkçesinde yazılmış olan yeni metinlerde “ne…ne…” bağlacının örneklerine rastlanmadığından bu çalışmada Tölögön Kasımbekov tarafından kaleme alınmış olan “Kelkel” ve “Sıngan Kılıç” adlı iki tarihî romanı içerisinde yaygın olarak kullanılan “ne…ne…” bağlacının geçtiği cümleler tespit edilmiştir. Tespit ettiğimiz cümleleri incelediğimizde “ne…ne…” bağlacının hiçbiri anlamının yanında cümle içerisinde karşılaştırılan unsurlardan “biri” ve “hepsi” ifadesini taşıyan “hem…hem…”, “da…de…”, “ya…ya…” ve “mı…mı…” görevinde de kullanıldığı görülmektedir. Ayrıca, “ne” bağlacının kullanımı ve kökeni ile ilgili yapılan çalışmalarda geçen değerlendirmelerle ilgili kısa bilgiler de verilmiştir. Bu çalışmalarda “ne” bağlacının kökeniyle ilgili kimi araştırmacılar Farsça kökenli olarak değerlendirmişken kimi araştırmacılar Türkçe olarak değerlendirmişlerdir. Yudahin, Kırgız Türkçesinde iki farklı “ne…ne…” bağlacının kullanıldığını, bunlardan birinin Farsçadan geçmiş olan “ne” bağlacı olduğunu ve diğerinin de Türkçedeki “ya…ya…” anlamında kullanılan “ne” bağlacı olduğunu belirtmiştir. Radloff ise Türkçenin kuzey lehçelerinde “ne…ne…” bağlacının kullanıldığı cümlelerin sonunda yüklemin olumsuzluk eki ile birlikte kullanıldığını, güney lehçelerinde ise Farsçada olduğu gibi “ne…ne…” bağlacının kullanıldığı cümlelerin yükleminin olumlu olarak yazıldığını dile getirmiştir.

Murataliyev, bu bağlacın kökeniyle ilgili Farsça olduğunu belirtmekle birlikte Kırgız Türkçesine Özbek ve Tatar Türkçesi aracılığıyla geçtiğini belirtmiştir. Bu bilgilerden yola çıkarak romanlardan “ne…ne…” bağlacının geçtiği cümleleri incelediğimizde yüklemlerinin çoğunun olumsuzluk eki aldığı tespit edilmiştir. “Ne…ne…” bağlacının bulunduğu cümlelerde fiilin ister olumlu, ister olumsuz olabilmesi ile ilgili çalışmanın devamında Deny ile Ediskun’un görüşlerine geniş bir şekilde yer verilmiştir.
HÂL TERCÜMESİ’NDEN HAREKETLE GILMAN KERİMÎ’NİN EĞİTİMCİ YÖNÜ
Authors: ÇAKMAK Cihan
Published: June 2023

Hayatın her alanında yeniliği savunan ve “ceditçiler” olarak adlandırılan aydınlar grubu çocuklara hiçbir faydası olmayan okulların çağın gereklerine uyarlanması şeklinde yola çıkmışlardır. Tabi ki her yenilik karşısında yüzyıllardır süre gelen gelenekçi anlayışa sahip zümreler tarafından tepkiyi de beraberinde getiriyordu. Tüm Türk dünyasında görüldüğü gibi Avrupa’nın kuzeyindeki İdil Ural coğrafyasında da bu yenilik hareketleri hızlı bir şekilde karşılık buluyordu. İsmail Gaspıralı’nın faaliyetlerinden ve açtığı modern okullardan cesaret alan bu aydın zümre onun liderliğinde söz konusu faaliyetleri kendi coğrafyalarında da uygulamaya koymuşlardır.

Kız çocuklarının okumasının dahi yasak olduğu ve karma eğitimin toplum yapısına uygun olmadığı, yabancı dil öğrenmenin, yani Rusça öğrenilmesinin kâfirlik alameti olarak görüldüğü bu eğitim anlayışında dinî ağırlıklı bir eğitim veriliyordu. Ancak Kur’an-ı Kerim’in merkeze alındığı bu eğitim anlayışında çocuklar 10-15 yıl Arapça, Farsça ve dinî bir eğitim aldıklarından okuma yazmanın ötesine geçemiyorlar, müspet bilimlerden ise hiç haberdar olmuyorlardı. Tüm bu yaklaşımların doğal bir sonucu olarak son derece işlevsiz, amaçsız ve yarar sağlamayan bir eğitim anlayışının hüküm sürdüğü bu metot karşısında bir çıkış yolu bulmaya çalışan aydın zümre çareyi Gaspıralı’nın açtığı ve başarılı bir şekilde uygulamaya koyduğu yeni öğretim metodunu benimsemekte buluyordu.

Bu çalışmada, Gılman Kerimî’nin oğlu ve Modern Tatar Edebiyatının kurucusu olarak kabul edilen, gazeteci, eğitimci, yazar ve siyasetçi Fatih Kerimî’nin babasının vefatı üzerine kaleme aldığı Hâl Tercümesi’nden hareketle eğitime dair görüşlerine yer verilmeye çalışılacaktır.
Distribution Hosting Capacity Tool
Authors: Alhadhrami Khalid
Published: June 2023

This study presents the methodology for the KAPSARC Distribution Hosting Capacity Tool (KDHCT). This tool can support the future of renewable energy in Saudi Arabia. The use of distributed energy resources (DERs), such as solar panels, energy storage and electric vehicles (EVs), is expected to increase. The KDHCT evaluates how many of these assets a particular distribution system can accommodate. The number of DERs and the load that an electric distribution system can reliably accommodate without significant grid upgrades is called its hosting capacity (HC) (Abad, Ma, and Han 2019). HC analysis informs electricity customers and utilities about the best places and times to install DERs and EVs on any distribution system. Thus, utilities can avoid reliability problems and costly distribution system upgrades.
Available calcium levels in central nervous system for Arzenazo III method
Authors: Rogério de Freitas Lacerda  , Isabela Cristina Sena Romano
Published: June 2023

The measurement and evaluation of changes in calcium levels between cellular compartments can provide important information for the understanding of biochemical processes, both physiological and pathological. The objective of this study was to validate the use of the calcium diagnostic kit (Arzenazo III) to tissue samples from the Central Nervous System. We used 96-well, flat-bottomed microplates with an internal diameter of 6.7 mm, total height of 12 mm and actual height of 10.705 mm, bottom thickness 1.295 mm, to carry out the tests and calculation parameters, therefore, the path optic was 5.729 mm with a total volume of 202 µL per well. The microplates were incubated at 37 °C for 2 minutes. Optical densities were measured at 630 nm on the Elx800 plate reader, (BioTek, VT, USA). According to the Arzenazo III Bioclin© calcium diagnostic kit. the absorbance of the tests/samples was normalized with the absorbance of the blank (colorimetric reagent 2 - Arsenazo III – Arzenazo III Bioclin© calcium diagnostic kit). PFC, Thalamus and Hippocampus were normalized by blank and presented respectively 0.1782 ± 0.0013; 0.1296 ± 0.0102; 0.0231 ± 0.0053; 0.0170 ± 0.0051; 0.0136 ± 0.0026. The calculation µg calcium / mg tissue obtained 0.4670 ± 0.1056 to sample PFC; 0.4322 ± 0.1228 to sample Thalamus and 0.1027 ± 0.0203 to sample Hippocampus. Although the limitations of the technique, the measurement of free calcium in the CNS tissues (PFC, Thalamus and Hippocampus) showed positive and satisfactory results, as an alternative and viable means for the quantification of calcium levels.
Formulation and in vitro evaluation of compression coated mebeverine HCl tablets for colon targeting
Authors: Anusha Gaddameedi  , Anand Kumar Yegnoor
Published: June 2023

The aim of the study was to develop colon targeted compression coated Mebeverine HCl (MEB) tablets using pH dependent, swellable and rupturable polymers for effective treatment of irritable bowel syndrome (IBS). The MEB loaded core tablets were prepared by direct compression method using CCM and CP as super disintegrating agents at different concentrations and evaluated for pre compression and post compression parameters. The optimized core tablets were further used to fabricate compression coated tablets using different ratios of Eudragit L100, Eudragit S100 as pH- dependent polymers, Keltone and Ethocel as swellable and rupturable polymers by modified compression method. Drug compatibility with excipients was checked by FTIR studies and results indicate no interaction. The precompression and post compression studies were within acceptable limits. In vitro dissolution studies were done for compression coated tablets to find out the lag phase, burst drug release and retard drug release The findings of this study concludes that the lag time of compression coated tablet can be modulated by combining with EL 100, ES 100, Keltone and Ethocel in different weight ratio. These designed tablet system was found to be satisfactory in terms of release of the drug after the predetermined lag time, thus the system can be target to release in the colon proximity. The compression coating technique can be successfully applied for MEB for colon targeting to treat IBS.
Phytochemical and nutritional composition of ethanol-water leaf extracts of Justicia secunda and Jatropha tanjorensis
Authors: Collins Obinna Keke  , Linus Ahuwaraeze Nwaogu  , Chidi Uzoma Igwe  , Kelechi Light Ekeke  , Winifred Njideka Nsofor
Published: June 2023

The study analyzed phytochemical and nutritional compositions of ethanol-water leaf extracts of Justicia secunda and Jatropha tanjorensis using standard methods. In both plants significant amounts of alkaloids, tannin and flavonoids were seen. J. tanjorensis had higher amount of saponin and cardiac glycoside. The quantitative phytochemical and anti-nutrient evaluation revealed J.tanjorensis had higher amount of phytochemicals including sapogenin, anthocyanin and anti-nutrient factors such as tannin, phytate and oxalate. The proximate analysis yielded carbohydrate as being most abundant in both plants with J.tanjorensis having higher (62.22 ±0.14%) against (61.52±0.12 %) seen in J.secunda. Fibre composition of both plants was low with 4.62±0.04% in J.secunda and 5.22±0.05% in J.tanjorensis. The most prevalent mineral element in J.secunda was magnesium (9.39±0.10mg/kg dry weight) while potassium (8.58±0.10mg/kg dry weight) was most prevalent in J.tanjorensis. Manganese was the least abundant in both plants. Eighteen different amino acids were found. His (4.76 ±0.08 µg/g) was the most abundant essential amino acid (EAA) in J.secunda, while Phe (5.78 0.04 µg/g) was the most abundant EAA in J.tanjorensis. Gly (4.85±0.03µg/g) and Pro (4.78±0.04 µg/g) was the most prevalent NEAAs in J.secunda and J.tanjorensis, respectively. The finding validates the richness of both plants in essential phytochemicals and other beneficial plant-based nutrients, and explains their traditional use in forkloric medicine practice.
Evaluation of the antiproliferative activity of three types of Annona muricata extract in the traditional treatment of cervical cancer induced in Wistar rats
Authors: Agossou Esse  , Akotegnon Rodrigue  , Savoeda Perside  , Behanzin G. Justin  , Sezan Alphonse
Published: June 2023

This study was concerned with the evaluation of the antiproliferative activity of Annona muricata in the traditional treatment of cervical cancer induced in Wistar rats. The aim of the present work was to compare the effect of ethyl, dichloromethane and ethyl acetate extracts of Annona muricata leaves to determine the most effective one on cervical cell differentiation in wistar rats. For this purpose, we made three extracts namely: ethyl extract, dichloromethane and ethyl acetate) from dried leaf powder of Annona muricata. The antiproliferative (anticancer) activity was evaluated by assaying the alkaline phosphatase and total protein parameters on cervical crushings of Wistar rats, in which cervical cancer was previously induced by exposure to Cycas revoluta extract through gavage of 100mg/kg of the ethyl extract of Cycas revoluta. The antiproliferative (anticancer) activity was effective by administration of a dose of 100 mg/kg of ethyl, dichloromethane and ethyl acetate extracts of Annona muricata leaves. This activity showed a variation of intensity according to the type of extracts. Thus the dichloromethane extract was the most active.
A study to assess the effectiveness of Self-instructional Module on knowledge regarding ABG among student nurses in selected college of city
Authors: Patricia Santosh Reddy  , Sneha Anil Mathurkar  , Aachal Shivprasad Pali  , Ashvini ramanand pal  , Puja Umashankar Neware  , Karina Brhamdeo Meshram  , Sonali Vilas Meshram  , Akansha Wamanrao Meshram  , Sanskriti Bhagwatrao Palwade  , Nikita Mahannand Pantawne  , Vishakha Sahasran Mate
Published: June 2023

Arterial blood gas analysis is a basic and useful laboratory test for the critical care of patient. ABG is an essential investigation for assessing clinical oxygenation and acid base status in critically ill patient, providing information about ventilation, oxygenation and acid base status, the three closely and interrelated physiological parameters that maintain pH homeostasis. Among student Nurses in selected college of city. An arterial blood Gas (ABG) tests explicitly blood taken from an artery ABG analysis assesses a patient’s partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2). The objectives of study were to assess existing level of knowledge regarding ABG analysis among the students nurses in selected college, Assess the post test knowledge regarding the ABG analysis among the student nurses in selected college, to assess the effectiveness of SIM on ABG analysis among the students nurses in Selected college, to find out the association between post-test levels of knowledge with selected Demographic level. A structured questionnaire to collect the knowledge score was use for data collection and the analysis was done with the help of inferential and descriptive statistics. The data collection was done from 60 samples from basic BSc nursing 3rd year students. The pre test shows 26.67% of the nursing student had poor level of knowledge score, 58.33% had average and 15% had good level of knowledge score. The post test shows 5% nursing student had average level of knowledge score 35% had good and 60% of nursing student have excellent level of knowledge score. The calculated t value is 15.07 are much higher than the tabulated value at 5% level of significance. Hence it is statistically interpreted that the self-instructional module on knowledge regarding ABG analysis among nursing students was effective
Patient motivation, satisfaction and attitudes towards involvement in inter-professional collaborative practice: A cross-sectional study
Authors: Shamima Akter  , Saddam Hossain  , Sk. Moniruzzaman  , Sultana Nasreen
Published: June 2023

During hospital-based long-term rehabilitation programmes, particularly for patients with spinal cord injuries, healthcare providers must make sure those patients are motivated, satisfied, and have positive views towards inter-professional collaboration among the team members. If they do this, patients will have a higher chance of sticking to their treatment plan, completing prescribed drugs, and getting better health results will have a higher chance of adhering to their treatment plan, taking the therapy recommended, and getting better health results if they comply with this. In a developing nation like Bangladesh, there is still much to learn about how patients feel about their care, what motivates them, and how they see the team that works with them. The purpose of the study was to investigate the level of motivation, attitudes, and satisfaction of people with spinal cord injury towards interprofessional collaborative practice. Quantitative research was applied to achieve the objectives. The overall motivation and satisfaction level of the patient with SCI towards interdisciplinary teamwork was high, 83.35% and 84.2%. Similarly, the patient attitude toward the team was just above average. The study findings could improve the rehabilitation sector's collaboration level by addressing strengths and weaknesses.
Perceptions of hospitality management students of Nueva Ecija University of Science and Technology to different learning modalities
Authors: May Nerissa S. Lopez  , Ralph Christopher M. Ramos
Published: June 2023

The study aimed to gather the perceptions of Hospitality Management students who have experienced both distance and traditional face-to-face learning. In today's fast-paced world, technology plays a crucial role in education. With the rise of the internet, technology-driven education has become the norm. However, it is essential to understand this impact on students, especially in the field of Hospitality Management. Hence, this study aimed to bridge the gap between technology-driven education and practical learning experiences. Quantitative description research was used in this study, which involved collecting data through a survey questionnaire. The study's respondents were 128 second, third, and fourth-year Hospitality Management students who were enrolled in the first semester of the academic year 2022-2023 at Gabaldon Campus, NEUST. A total sample technique was used to select the respondents. The results showed that most students preferred traditional face-to-face learning over distance learning. They felt that they could retain the information better when taught in a traditional classroom setting. The students also said they preferred the interaction and hands-on experience they got from traditional face-to-face learning. However, the study also found that students appreciated the flexibility distance learning offered. They felt that they could study at their own pace and had the option to pause the lecture whenever needed. This made the learning process less stressful for them. Based on the results, the researchers recommend that future studies may use this study as a basis for further research in the field. They also suggested that teachers may integrate brainstorming activities to improve the skills of their students. Additionally, they recommended that teachers integrate mobile phones into the classroom to enhance teaching flexibility. In conclusion, this study aimed to gather the perceptions of Hospitality Management students who have experienced both distance learning and traditional face-to-face learning. The results showed that students preferred traditional face-to-face learning but appreciated the flexibility distance learning offered. The researchers recommend that teachers may integrate brainstorming activities and mobile phones in the classroom to enhance the learning experience for their students.