bluuebunny/crossref_metadata_2025 huggingface dataset:
FEATURES OF POWER DETERMINATION OF AUXILIARY-EMERGENCY DRIVE MOTION OF A SHIP WITH A COMBINED DIESEL-ELECTRIC POWER PLANT
Authors:   Donetsk National Technical University, Rak A. , Busher V. ,   National University “Odessa Maritime Academy”, Glazeva O. ,   National University “Odessa Maritime Academy”
Published: May 2021

Purpose. The paper compares the traditional method of calculating the parameters of electric motion of ships in auxiliary emergency modes at low speeds of the vessel with another, simplified because it does not require the use of a large number of diagrams to determine the resistance of the vessel. But according to a simplified method for this example – a container ship with a capacity of 16,000 containers with the main engine capacity of 61776 kW, a synchronous machine with a capacity of up to 6 MW in engine mode, and three diesel generators with an electric capacity of 3187 kW – 39 % more power is obtained. Own experience of operation of the vessel in modes with electric movement – loading of diesel generators in this mode on the vessel about 70 % that is received by calculations. Thus, when upgrading the propulsion system or designing new vessels, it is advisable to compare the results of two calculations of the power of diesel generators at the limit of the minimum stable speed of the main engine and choose the larger of the results. Methodology. Comparison of specific and absolute fuel consumption, made on the basis of known approximation polynomials for low- and high-speed types of diesel of the company at auxiliary emergency movement shows that at the movement from high-speed diesel generators MAK8M32S fuel consumption decreases by 24 %, then at the maintenance of the main engine 12 RTflex-96C from WÄRTSILÄ-SULZER. Results. Therefore, the use of electric motion allows you to save engine power of the main engine, reduce fuel consumption. This ratio is observed on most maritime transport vessels. And given that diesel generators operate at almost optimal load, and the main engine – at idle, electric motion provides a significant reduction in harmful emissions into the atmosphere. The latter is also true for a ship where the synchronous engine is located behind the main engine, although fuel consumption, in this case, increases by 32 %. Figures 9, tables 6, references 15.
The Creation of the Kingdom of Serbs, Croats and Slovenes in Montenegro’s Memory
Authors: Domachowska Agata
Published: May 2021

The aim of this paper is to investigate the position and role occupied by the memory of events of 1918–1919 in shaping and strengthening the national identity of Montenegrins. It begins with a theoretical introduction concerning the role of historical events in shaping national identity. Then it presents in a synthetic manner the situation of Montenegro before the outbreak of the Great War. The subsequent subsection focuses on the analysis of events related to the end of World War i. The last part employs the technique of narrative analysis in order to analyze the contemporary policy of the Montenegrin authorities. This article should be treated as a sketch of the Montenegrin policy of memory, the ways in which the end of the wwi is remembered, and how it is used for shaping national identity.
Over-expression of mannose-P-dolichol utilization defect 1 in human endometrial cancer.
Authors: Mamoor Shahan
Published: May 2021

Gynecologic cancers including cancers of the endometrium are a clinical problem (1-4). We mined published microarray data (5, 6) to discover genes associated with endometrial cancers by comparing transcriptomes of the normal and hyperplastic endometrium to endometrial tumors from humans. We identified mannose-P-dolichol utilization defect 1, encoded by MPDU1, as among the most differentially expressed genes, transcriptome-wide, in cancers of the endometrium. MPDU1 was expressed at significantly higher levels in endometrial tumor tissues as compared to the endometrium. Importantly, in human endometrial cancer, primary tumor expression of MPDU1 was correlated with recurrence-free survival in black patients with low mutational burden. MPDU1 may be a molecule of interest in understanding the etiology or progression of human endometrial cancer.
The Impact of COVID-19 on U.S. Adolescents: Loss of Basic Needs and Engagement in Health Risk Behaviors
Authors: Shroff Akash , Fassler Julia , Fox Kathryn , Schleider Jessica L.
Published: May 2021

Across the United States, the COVID-19 pandemic created myriad challenges for youth and families, including losses of basic needs which may be associated with increased use of maladaptive coping behaviors. In a sample of 2,491 U.S. youth (ages 13-16), demographic differences in loss of basic needs and maladaptive coping were assessed using regression models. More than 21% of adolescents endorsed losing one or more basic needs and 83% endorsed use of maladaptive coping strategies. Minoritzed youth reported losing more basic needs (ps < 0.05), and greater reliance on maladaptive coping behaviors (ps < 0.05), relative to non-minoritized peers. Healthcare providers and teachers must consider basic need losses while structuring support for youth during and beyond the COVID-19 pandemic.
Trajectories of depression and anxiety symptoms over time in the transition to university: Their co-occurrence and the role of self-critical perfectionism
Authors: Levine Shelby L. , Tabri Nassim , Milyavskaya Marina
Published: May 2021

Little is known about how mental health symptoms develop during the transition to university. Most anxiety and depression research fail to consider how symptom development differs over time across different individuals, and how symptom co-occurrence influences the severity of mental heath problems. Students (N = 658) completed online surveys on mental health prior to starting university and every 2 months until April. To better understand mental health problems during this transitional period, latent class growth curve analyses were run to determine how anxiety and depressive symptoms co-develop over time, as well, if self-critical perfectionism was a transdiagnostic risk factor for more severe symptom trajectories in this transition. About 40% of students experienced depression and anxiety symptoms prior to entering/ during the transition to university. There is substantial variation between students in terms of how they experience depression and anxiety symptoms, and research needs to take this heterogeneity into account to properly identify which students might benefit most from resources. Self-critical perfectionism was a transdiagnostic risk factor, such that students higher in this trait experienced more severe anxiety and depressive symptom trajectories during this transition. This research further implicates the importance of understanding and studying individual differences in symptom development.
Gender, Genes, and Income: How Equality of Opportunity Changed in Norway Across the 20th Century
Authors: Isungset Martin Arstad , Baier Tina , Lyngstad Torkild Hovde
Published: May 2021

The income gender gap shrank dramatically in western democracies over the twentieth century. We ask whether genetic influences on lifetime income, i.e. the heritability, is the same for men and women across birth cohorts. We interpret heritability as achievement and shared environ-ments as social ascription on the basis of gender. We use data on 11,677 twin pairs born in Norway between 1915 and 1991 linked with full-population administrative income data covering the years 1967-2016. The heritability of lifetime income doubled across birth cohorts as women faced fewer social barriers to earn income. The increase in heritability and decrease in gendered shared environments indicate more equality of opportunity between gender for later-born cohorts. However, it also shows that in an extensive welfare state like Norway where gender equality has been a political priority since the 1950s, equality of opportunity was low until very recently. Furthermore, when we study men and women separately, the heritability is lower for women than for men, showing that genes are not pathwayed to influence lifetime income equally. Although we argue that genetically informed designs can be used to evaluate equality of opportunity between genders, we discuss the many interpretive challenges that remain.
Penyelesaian Tanah Sisa pada Pengadaan Tanah Pembangunan Jalan Tol di Kabupaten Karanganyar
Authors: Sudiarka Fredi Elroi , Budhiawan Haryo , Prasetyo Priyo Katon
Published: May 2021

Abstract: Article 35 of Law Number 2 of 2012 states that if there is residual land, the rightful party can request compensation in full for the leftover land that can no longer be used in accordance with the original designation and use. However, in its implementation, the implementing committee of the land acquisition still had difficulty especially for determining the criteria of the leftover land that could be compensated. Based on that issue, this study intend to (1) determining the characteristics of the leftover land that can be compensated; (2) knowing who has the right to determine the leftover land that can be compensated; (3) knowing the process of settling leftover land in land acquisition. The method used in this study is a qualitative research method with a descriptive approach to the case study method. The results of the study show that compensation that can be directly compensated for leftover land is land that has an area of less than 100m². For those who are more than 100m², the land acquisition implementation committee considers the shape of the remaining land, the leftover land area and access roads. The right to determine the leftover land is the land acquisition committee. Settlement of the leftover land carried out in Karanganyar Regency is based on a Circular from the Director General of Land Procurement.Keywords: Land Acquisition, Leftover Land, CompensationIntisari: Pasal 35 Undang-Undang Nomor 2 Tahun 2012 menyebutkan bahwa apabila terdapat tanah sisa, pihak yang berhak dapat meminta ganti kerugian secara utuh terhadap tanah sisa yang sudah tidak dapat digunakan sesuai dengan peruntukan dan penggunaannya semula. Namun dalam pelaksanaannya panitia pelaksana pengadaan tanah masih kesulitan untuk menentukan kriteria tanah sisa yang dapat diberikan ganti kerugian. Berdasarkan hal tersebut penelitian ini bertujuan untuk (1) mengetahui karakteristik tanah sisa yang dapat diberikan ganti kerugian; (2) mengetahui siapa yang berhak menentukan tanah sisa dapat diberikan ganti kerugian; (3) mengetahui proses penyelesaian tanah sisa pada pengadaan tanah. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif pendekatan deskriptif dengan metode studi kasus. Hasil dari penelitian menunjukkan bahwa ganti kerugian yang dapat langsung diberikan ganti kerugian adalah tanah sisa yang memiliki luas kurang dari 100m². Untuk yang lebih dari 100m², panitia pelaksana pengadaan tanah mempertimbangkan mengenai bentuk tanah sisa, luas tanah sisa dan akses jalan. Yang berhak menentukan tanah sisa adalah panitia pengadaan tanah. Penyelesaian tanah sisa yang dilakukan di Kabupaten Karanganyar berdasarkan Surat Edaran dari Direktur Jenderal Pengadaan Tanah.Kata Kunci: Pengadaan Tanah, Tanah Sisa, Ganti Kerugian
Pengantar Redaksi
Authors: Redaksi Redaksi
Published: May 2021

Puji syukur kepada Tuhan Yang Maha Esa, karena edisi ketiga Jurnal Tunas Agraria (JTA) ini, dapat kembali terbit ke hadapan para pembaca dengan segala kelebihan dan kekurangannya. Edisi ini mengangkat tema sekitar  Tata Ruang, Pengadaan Tanah, Pendaftaran Tanah, dan Pengukuran.
Antygona
Authors: Anouilh Jean , Filonik Jakub
Published: May 2021

The translation of Antigone, a play by Jean Anouilh, inspired by Sophocles’ tragedy, written in 1942 and first staged in occupied Paris in 1944. The book is addressed to general readers: students of secondary schools and universities and everyone interested in French drama, intellectual history of the 20th century and the reception of classical culture.
Lepton Flavor Violating $h\to\tau\mu$ decay induced by leptoquarks
Authors: Arroyo-Ureña M. A. , Gaitán R. , Montes de Oca J. H. , Sánchez-Vélez R.
Published: May 2021

The flavor changing neutral current decay $h\to\tau\mu$ is studied in a renormalizable scalar leptoquark model with no proton decay. Analytical expressions for the one-loop level contributions of a scalar leptoquark to the decay width of the process $h\to\tau\mu$ are presented. We find a viable model parameter space via the current constraints on the muon ($g-2$), the decay $\tau\to\mu\gamma$, the LHC Higgs boson data and the direct leptoquark searches at the LHC. Then, we evaluate branching ratio of the decay $h\to\tau\mu$induced by leptoquarks; we find that it is of the order of $10^{-8}-10^{-7}$ ($10^{-8}$; $10^{-9}-10^{-8}$)for a scalar leptoquark mass equal to $m_{\Omega_{5/3}}=1$ TeV ($m_{\Omega_{5/3}}=2$; $m_{\Omega_{5/3}}=10$ TeV). Finally, we evaluate the number of events produced at future hadron colliders from both the $h\to\tau\mu$ decay and the potential Standard Model background finding a potentialevidence for the $h\to\tau\mu$ decay.
Prediction of electronic and optical properties for Zn1-xCdxSeyTe1-y quaternary alloys: First-principles study
Authors: Kada BENCHIKH , Benchehima M. , Abid H. , Chaouche C.
Published: May 2021

In the present work, the density functional theory (DFT) was performed for the investigation of the structural, electronic and optical properties of the Zn1-xCdxSeyTe1-y quaternary alloys using the full potential linearized augmented plane wave (FP-LAPW) method. For the calculations of the structural properties we have used the Perdew-Burke-Ernzerhof generalized gradient approximation (GGA-PBEsol). On other hand, the electronic properties have been computed within the local density approximation (LDA) in adding to the Tran-Blaha modified Becker-Johnson (TB-mBJ) approach. Our results indicate that the lattice constant, as well as the bulk modulus and the energy gap for the Zn1-xCdxSeyTe1-y quaternary show almost linear variations on the concentration x (0.125≤x≤0.875). In addition, the simulated band structures for theZn1-xCdxSeyTe1-y quaternary exhibits a direct-gap for all concentrations. Moreover, low bowing parameters are observed. Also, some interesting optical properties such as dielectric constant, refractive index, extinction coefficient, absorption coefficient and reflectivity have been calculated by using the TB-mBJ method.  The results of our computations shows that theZn1-xCdxSeyTe1-y quaternary alloy is a promissing candidate for optoelectronic applications. It is noteworthy that the present work is the first theoretical study of the quaternary of interest using the FP-LAPW calculations.
Homophobia and Antisemitism in Otto Julius Bierbaum’sPrinz Kuckuck(1907/08)
Authors: Wolf Benedikt
Published: May 2021

Starting from existing scholarship on the relationship among masculinity, sexuality, and Jewishness in the German-language cultural sphere, this article analyzes the connection between antisemitism and homophobia in Otto Julius Bierbaum’s fin-de-siècle novel Prinz Kuckuck. By tracing the respective paths of the Jewish protagonist and his male homosexual counterpart, the article elaborates on the specific versions of Jewishness and male homosexuality that Bierbaum’s novel creates. It can be shown that the novel exposes both the Jewish and the homosexual character as deficient and harmful. The novel, however, does not restrict itself to mere parallelization but establishes an intrinsic connection between the Jewish and the male homosexual character by integrating homosexual codes into the Jew’s “parasitic” repertoire. The article concludes by offering an explanation of this connection that draws on Moishe Postone’s critique of modern antisemitism. Antisemitism and homophobia are shown as two complementary and intrinsically connected ways of dealing with two dimensions of the experience of modernity: capitalism and social contingency.
Terms of repair works and forecasting of terms of service of contacts of disassembly type in conditions of incomplete of output information
Authors:   National University of Life and Environmental Sciences of Ukraine, Voloshin S. M.
Published: May 2021

Collapsible contact joints are the most numerous elements of electrical installations. The efficiency of the contacts, their reliability to a large extent depends on the modes of electric current and temperature, contact pressure, etc. Modification of modes and operation time lead to an increase in the resistance of the contacts, the temperature of their heating and possible thermal destruction. Traditional means for controlling the pressure in the contacts when changing the temperature regime are steel plate springs. Previous investigations have established that these means only partially solve the problem of regulation of contact pressure. An alternative to traditional means is the innovative development of dynamic pressure control tools based on the use of functional alloys with the shape memory effect. The mathematical analysis of terms of carrying out repair works and service life of collision type contacts with the use of probability theory in the conditions of incompleteness of the initial information is carried out. The research substantiates that the use of dynamic method of control of the thermomechanical regime of collapsible contacts allows to stabilize pressure and extend the life of collapsible contacts by 3-4 times.
Modeling of soil tilling and planting unit
Authors:   State Scientific Institution ", Gayday T. V. ,   Ukrainian Research Institute for Forecasting and Testing of Machinery and Technologies for Agricultural Production named after Leonid Pogorily"
Published: May 2021

This research is aimed at increasing the efficiency of the technical and technological process of small-seeded green manure crops sowing by combining technological operations of a soil-tilling and planting unit (STPU) and improving the design parameters of the scatterer. A scheme of a soil-tilling and planting unit with a scatterer and a control means is proposed, and a concept of the functioning of the technological process of a soil-tilling and planting unit is determined. To study the technological process of small-seeded crops sowing, which is implemented by the STPU, it is important to build a mathematical model of the dynamics of the process for further optimization of both the process itself and the parameters of the sowing apparatus. The simulation includes the development of a model of the dynamics of the STPU travel on the field, taking into account the corresponding traction and resistance forces, the turning moments and the moments of resistance to turning of the tractor, as well as the calculation of the parameters of the seed output from the seed hopper, the dynamics of its travel in the seed tubes to the point of contact with the scatterer and the seed scattering formula on the soil after exiting the seed tubes. The obtained models allow us to determine the technical parameters of various working devices included in the STPU, from the point of view of their compliance with the activities for the quality of the task. The main attention is focused on determining the design parameters of STPU elements based on the construction and research of relevant mathematical models and calculation expressions. In this direction, a study was carried out to determine the optimal components: geometric design parameters and the angular velocity of the seed roller (wк), the initial seed speed in the seed tubes specified by the compressor fan (Vcf), the angle of inclination of the diffuser plate (β) and its height above the soil surface (Hs)) An advanced mathematical model allows you to simulate tillage and sowing units with different working widths.
Dynamic calculation of screw conveyor of safety clutch
Authors:   National University of Life and Environmental Sciences of Ukraine, Trokhaniak O. M.
Published: May 2021

The article presents a scheme of screw conveyor of the safety clutch, the calculation carried out by a dynamic of its work. Graphically depending is present on the results of which can investigate the influence of various parameters of the system on the dynamic loads in the drive links of the conveyor. Also presented stand for the experimental test engine and a comparison of theoretical and experimental research work overload clutch of screw conveyor.
Optimization methods of operating costs on road transport in international transportation
Authors:   National University of Life and Environmental Sciences of Ukraine, Bondariev S. I.
Published: May 2021

Transport processes research are closely related to the economic and operational performance of road transport. During planning road transportation, the most important factor is the transport services cost. Known fact that most of the transportation costs are car fuel. The share of car fuel in the transport tariff cost can be 25-50% (depending on the working conditions of vehicles). Therefore, research that is associated with improving the vehicles efficiency by reducing variable costs is appropriate and relevant. The article presents the results of research on the planning of transport processes in the road transport performance in international road transport for the return flight and calculating methods the demand for the amount of fuel purchased in different countries with different prices. The author presents the results of theoretical and experimental research the adequacy of the mathematical model (methodology). The specified mathematical model consists in substantiation of a technique of calculation of quantity of car fuel, definition of the variable factors influencing volumes of fuel expenses, calculation of correction factors (total) received on the basis of technical and operational indicators of vehicles and the influencing factors connected with features of road transport work. . The second part of the research contains the results of the development of an algorithm development to calculate the total cost of automotive fuel, which was purchased at different prices in several countries. Thus, the main purpose of research is the task of substantiating the algorithm (mathematical model – methodology) for determining fuel costs by the criterion of the highest use of fuel in countries at the lowest prices.
Justification of risk-based approach of operation of mobile agricultural equipment on example of details of separate units of tractors
Authors:   National University of Life and Environmental Sciences of Ukraine, Voynalovich O. V. , Holopura S. M. ,   National University of Life and Environmental Sciences of Ukraine
Published: May 2021

It is shown that in order to justify the extension of the service life of the machine beyond the resource set by the developers, it is necessary to focus on the allowable risks of accidents that can lead to accidents. After all, today for mobile agricultural machinery, the operation of which is associated with high-risk work, the concept of acceptable (acceptable) risk is not used, which does not allow to assess the danger of being on fields, farms and roads without machinery, with exhaustion of installed resources. The purpose of researches is to justify the permissible risk of exploitation of mobile agricultural machinery, in array of details and elements of constructions which have accumulated defects (damage). This paper analyzes the kinetics of accumulation of operational defects in the array of parts of individual components (systems) of tractors. MTZ-80 tractors (82) were chosen as the object of research, as one of the most common in Ukraine. To detect cracks, a developed eddy current flaw detector was used, the sensitivity of which allowed to find cracks several millimeters or larger in length without preparing the surface of the controlled parts. It is shown that the kinetic dependences of the accumulation of operational defects in the parts of tractor units in the analyzed range of service life are monotonically increasing, which can be described by exponential functions with a sufficiently high reliability. It is noted that the obtained dependences are similar to the kinetic dependences of the accumulation of static and dynamic (fatigue) damage obtained as a result of laboratory tests of samples of construction materials, which allows to use approaches to the criteria of the limit state of laboratory samples due to the power load to establish the boundary life of mobile agricultural machinery. However, the kinetics of the intensity of the occurrence of operational cracks in the array of tractor parts is not monotonous and has a maximum in the range of about 11-13 years of operation. This service life can be used as a criterion to stop the operation of the tractor, to carry out defectoscopy of parts and to replace defective parts. With such a long service life of the tractor, there is the greatest probability of sudden destruction of the tractor components and the creation of emergencies.
Validity and Reliability Measurement of Bengali Translated Questionnaire for Urinary Incontinence Diagnosis
Authors: Nipa Shamima Islam , Sriboonreung Thanyaluck , Paungmali Aatit , Phongnarisorn Chailert , Patwary Md.Fazlul Karim
Published: May 2021

Objective: The aim of this study was to translate and verify the validity and reliability of the Bengali translated questionnaire for Urinary Incontinence Diagnosis (QUID), to ensure the diagnosis of urinary incontinence in Bangladesh.Material and Methods: Adaptation and psychometric properties testing of the Bengali-QUID were conducted with 67 respondents. Twenty respondents were included for pre-testing and adaptation; whereas, 47 respondents were considered for test-retest reliability. The content validity of the questionnaire was measured by expert opinion. Cornbach’s alpha statistical test was used to measure the internal consistency of the questionnaire, while the test-retest reliability was measured using the Intra-Class Correlation (2,1) model.Results: Content validity for all items of the questionnaire was >0.75. In addition, the Cronbach's Alpha values for interitem correlation for Stress Urinary Incontinence and Urge Urinary Incontinence were (α>0.8) and (α>0.7), respectively. Furthermore, the reliability of the Bengali-QUID questionnaire had an Intra-class correlation score of 0.76.Conclusion: This study demonstrated that the Bengali version of QUID questionnaire was highly valid, and reliable for diagnosis of urinary incontinence among Bangladeshi women.
EĞİTİMDE BİREYİ ANLAMAK VE GİZİL YETENEK
Authors: GÜNAY Tuğrul , GÜRBÜZER Birgül
Published: May 2021

The aim of the study make inferences in the context of educational philosophy about how the latent talents in people who are the object and subject of education emerge and how they are evaluated. At the same time, it is to bring Rousseau and John Locke's views on educational philosophy to the literature. In this direction, by searching the relevant literature; evaluations and comparisons have been made. The research results, suggestions for other studies to be carried out were presented. It is thought that the determined recommendations will guide the creation of other studies.
Phytochemical Screening, Total Phenolics Contents and in vitro Antioxidant Activity of Salvia officinalis, Satureja calamintha, Mentha pulegium and Marrubium vulgare
Authors: Belkacem N. , Azzi R. , Djaziri R.
Published: May 2021

This study was designed to evaluate the antioxidant activity of phenolic compounds of for Lamiaceae: Salvia officinalis, Satureja calamintha, Mentha pulegium and Marubium vulgare using ferric reducing power (FRAP) and radical scavenging method (DPPH). Preliminary phytochemical analysis shows that the major constituents of crude extracts (Hydromethanolic, hydroacetonic) are tannins, saponins, quinones, flavonoids, terpenoids and reducing compounds in the four plants. In quantitative analysis, variable polyphenols, flavonoids and condensed tannins content are recorded. The highest polyphenols content is that of the aqueous/methanol crude extract of Salvia officinalis (188.92 ± 1.19 mg GAE/ gE), followed by aqueous/acetone crude extract of Mentha pulegium (176.55 ± 2.49 mg GAE/gE). Flavonoids and condensed tannins content of crude extract showing a high content in aqueous/methanol extract of Mentha pulegium and Satureja calamintha (93.64 ± 0.26mg EQC/gE and 25.44 ± 0.71 mg EQC/gE), respectively. Scavenging activity of the free radical DPPH, revealed that the aqueous/methanol extract of Salvia officinalis shown a relatively high antioxidant activity (IC50 = 1.07 μg/ml) compared with ascorbic acid (IC50 = 0.91 μg/ml). FRAP method revealed that the extracts of Mentha pulegium showed the highest power to reduce iron (EC50 = 0.147 mg/ml), but lower than that of ascorbic acid (EC50 = 0.057 mg/mL).
Status of ADR in Existing Laws of Pakistan: A Brief Study
Authors: Hassan Abida , Malik Dil Muhammad
Published: May 2021

This article highlights already working of Alternative Dispute Resolution (ADR) in existing laws of Pakistan and mentions the provisions in which Alternative Dispute Resolution (ADR) is already available in various federal as well as provincial laws of Pakistan, but unluckily has not been applied or followed properly and new legislations have been enacted. There is only a need to create awareness on the said topic. This article also points out the benefits of this system because it provides justice to people at their doorstep but also reduces the backlog of cases and lessens the burden on courts so that they can give genuine attention to matters serious in nature. There is a need to introduce this system at all levels, which will be beneficial not only for the legal system in particular but also for the social system in general. This article creates not only awareness but also identifies the weaknesses of the legal system in Pakistan and link them with the problems of this country; it makes some suggestions for making this system more effective.
Saffron and depression
Authors: Asgary Sedigheh
Published: May 2021

Throughout the centuries, people have used the dried stigma of Crocus sativus that is known as "saffron" for medicinal and nutritional purposes [1]. Studies have shown that not only is saffron well worth the money, but also, its bioactive compounds (including crocin, precrocin, and safranal that are responsible for color, taste and fragrance respectively) play a crucial role in the central nervous system to positively affect conditions such as anxiety and depression [2-5]. Saffron compounds are also neuroprotective and anxiolytic and can benefit learning and memory impairments [6].
Fit for Purpose: Analyzing the German Archiving and Exchange Interface for Medical Practice Management Systems
Authors: Barkow Linus , Meincke Oliver , Ulrich Hannes , Ingenerf Josef
Published: May 2021

The archiving and exchange interface for practice management systems of the Kassenärztliche Bundesvereinigung, defined by FHIR (Fast Healthcare Interoperability Resources) profiles with extensions, describes a new opportunity for medical practitioner to change the system provider. The expectation is to transfer an entire database of a legacy system to another system without data loss. In this paper the potential loss of data is analyzed by comparing parameters. The results show that during an import on average 75% of the parameters per profile are supported and on average only 49% of the reviewed parameters, existing in the exporting system, could be represented based on the interface specification.
Feasibility Queries in Distributed Architectures – Concept and Implementation in HiGHmed
Authors: Wettstein Reto , Hund Hauke , Kobylinski Insa , Fegeler Christian , Heinze Oliver
Published: May 2021

Medical routine data promises to add value for research. However, the transfer of this data into a research context is difficult. Therefore, Medical Data Integration Centers are being set up to merge data from primary information systems in a central repository. But, data from one organization is rarely sufficient to answer a research question. The data must be merged beyond institutional boundaries. In order to use this data in a specific research project, a researcher must have the possibility to query available cohort sizes across institutions. A possible solution for this requirement is presented in this paper, using a process for fully automated and distributed feasibility queries (i.e. cohort size estimations). This process is executed according to the open standard BPMN 2.0, the underlying process data model is based on HL7 FHIR R4 resources. The proposed solution is currently being deployed at eight university hospitals and one trusted third party across Germany.
Concept and Implementation of Data Usage Proposal Process Based on International Standards in SMITH
Authors: Klötgen Marcel , Fiege Eric , Houta Salima
Published: May 2021

Accessing secondary-use healthcare data in Germany requires contracting with each organization that acts as a data provider. The SMITH Service Platform offers a central access point for scientists, facilitating contracting as part of an integrated data use and access process with several Data Integration Centers (DIC) at once. Process support is realized by a central Business Process Engine (BPE), which manages process definition and process control, combined with a central IHE infrastructure. The use of IHE XDS and IHE XDW profiles enables the exchange of process instance information with multiple distributed visualization and user interaction tools for provided user tasks based on international standards. User task information include structured forms for submitting instructions and results as task input and output for the users, and are synchronized between the shared process instance and the BPE. A reference user interface is also provided with the SMITH Marketplace. In the future, further standardization efforts regarding the structured forms and the use of the IHE XDW profile should be pursued.
Oncology on FHIR: A Data Model for Distributed Cancer Research
Authors: Lambarki Mohamed , Kern Jori , Croft David , Engels Cäcilia , Deppenwiese Noemi , Kerscher Alexander , Kiel Alexander , Palm Stefan , Lablans Martin
Published: May 2021

In the field of oncology, a close integration of cancer research and patient care is indispensable. Although an exchange of data between health care providers and other institutions such as cancer registries has already been established in Germany, it does not take advantage of internationally coordinated health data standards. Translational cancer research would also benefit from such standards in the context of secondary data use. This paper employs use cases from the German Cancer Consortium (DKTK) to show how this gap can be closed using a harmonised FHIR-based data model, and how to apply it to an existing federated data platform.
Machine Learning to Identify Fake News for COVID-19
Authors: Isaakidou Marianna , Zoulias Emmanouil , Diomidous Marianna
Published: May 2021

International Organizations are seriously concerned about the fake news phenomenon. UNESCO has defined the term of misinformation/disinformation, which are the two faces of fake news. European Commission has conducted a survey about “Fake News” through EU citizens to estimate the awareness and people behaviour related to the appearance of fake news and disinformation on electronic. The findings are quite worrying, since about 40% come across fake news daily and 85% evaluate fake news as a problem. The aim of this work is to introduce an Artificial Intelligence approach, the Decision Trees algorithm to identify fake news on the COVID-19.
Prescreening in Oncology Using Data Sciences: The PreScIOUS Study
Authors: Ansoborlo Marie , Dhalluin Thibault , Gaborit Christophe , Cuggia Marc , Grammatico-Guilllon Leslie
Published: May 2021

The development of precision medicine in oncology to define profiles of patients who could benefit from specific and relevant anti-cancer therapies is essential. An increasing number of specific eligibility criteria are necessary to be eligible to targeted therapies. This study aimed to develop an automated algorithm based on natural language processing to detect patients and tumor characteristics to reduce the time-consuming prescreening for trial inclusions. Hence, 640 anonymized multidisciplinary team meeting (MTM) reports concerning lung cancer were extracted from one teaching hospital data warehouse in France and annotated. To automate the extraction of 52 bioclinical information corresponding to 8 major eligibility criteria, regular expressions were implemented and evaluated. The performance parameters were satisfying: macroaverage F1-score 93%; rates reached 98% for precision and 92% for recall. In MTM, fill rates variabilities among patients and tumors information remained important (from 31.4% to 100%). The least reported characteristics and the most difficult to automatically collect were genetic mutations and rearrangement test results.
Using Primary Care Data to Report Real-World Pancreatic Cancer Survival and Symptomatology
Authors: Jeffreys Nathan , Dambha-Miller Hajira , Fan Xuejuan , Ferreira Filipa , Liyanage Harshana , Sherlock Julian , Williams John , Rice Rebecca , Stunt Ali , Faithfull Sara , Gatenby Piers , Lemanska Agnieszka , de Lusignan Simon
Published: May 2021

Pancreatic cancer is the 10th most common cancer diagnosed; despite recent advances in many areas of oncology, survival remains poor, in part owing to late diagnosis. Whilst primary care data are used widely for epidemiology and pharmacovigilance, they are less used for observing survival. In this study we extracted a pancreatic cancer cohort from a nationally representative English primary care database of electronic health records (EHRs) and reported on their symptom and mortality data. A total of 11, 649 cases were identified within the Oxford Royal College of General Practitioners (RCGP) Clinical Informatics Digital Hub network. All-cause mortality data was recorded for 4623 (39.69%). Mean age at recording of cancer diagnosis was 71.4 years (SD 12.0 years). 1-year and 5-year survival was 22.06% and 3.27% respectively. Within a multivariate model, age had a significant impact on survival; those diagnosed under the age of 60 had the longest survival, as compared to those age 60 – 79 (HR: 1.36, 95% CI: 1.20 – 1.54, p < 0.001) and 80+ (HR: 2.13, 95% CI: 1.86 – 2.44, p < 0.01). Symptomatology was examined; at any time point abdominal pain was the most commonly reported symptom present in 5271 cases (45.2%), but within the 12 months preceding diagnosis jaundice was the most common feature, present in 2587 patients (22.2%). Future studies clarifying other contributing factors on survival outcomes and patterns of symptomatology are needed; primary care EHRs provide an opportunity to evaluate real-world cancer patient cohort data.
Patient-Generated Health Data (PGHD) Interoperability: An Integrative Perspective
Authors: Hussein Rada , Crutzen Rik , Gutenberg Johanna , Kulnik Stefan Tino , Sareban Mahdi , Niebauer Josef
Published: May 2021

With advances in Digital Health (DH) tools, it has become much easier to collect, use, and share patient-generated health data (PGHD). This wealth of data could be efficiently used in monitoring and controlling chronic illnesses as well as predicting health outcome. Although integrating PGHD into clinical practice is currently in a promising stage, there are several technical challenges and usage barriers that hinder the full utilization of the PGHD potential in clinical care and research. This paper aims to address PGHD opportunities and challenges while developing the DH-Convener project to integrate PGHD into the Electronic Health Record in Austria (ELGA). Accordingly, it provides an integrative technical-clinical-user approach for developing a fully functional health ecosystem for exchanging integrated data among patients, healthcare providers, and researchers.
Fake News and Disinformation in Health Care- Challenges and Technology Tools
Authors: Tsirintani Maria
Published: May 2021

The aim of this study is to define and analyze the phenomenon of fake news and disinformation from social media in healthcare ecosystem. Social media and web platforms can be used to spread misinformation, which produces harmful consequences to global health and well-being. A qualitative research was carried out by using semi structured interview with experts for collecting the data investigating the social, legal and technical environment that promote this phenomenon. In order to shed some light, software tools and web platforms are suggested to those in charge of educating users on their best use of internet for this purpose.
Environment Monitoring System Raising Awareness of Sensitive Inhabitants Based on Regression Predictive Modelling
Authors: Bogdan Razvan , Crişan-Vida Mihaela , Muresan Razvan , Barmayoun Darius , Stoicu-Tivadar Lăcrămioara
Published: May 2021

The system described in this paper notifies the user about possible indoor environmental hazards through a smartphone application. Events such as house fires or increasing levels of dangerous substances are detected; thus, raising the awareness level in regard to the quality of the indoor environment. Our solution is a system that monitors the environment within a room in order to avoid undesired health hazards. It consists of a data collection subsystem, a cloud database which stores the collected information and a mobile application that displays and notifies the user in case of critical events that might negatively affect the health condition.
Machine Learning Algorithms Reveals Country-Specific Metagenomic Taxa from American Gut Project Data
Authors: Liñares-Blanco Jose , Fernandez-Lozano Carlos , Seoane Jose A. , Lopez-Campos Guillermo
Published: May 2021

In recent years, microbiota has become an increasingly relevant factor for the understanding and potential treatment of diseases. In this work, based on the data reported by the largest study of microbioma in the world, a classification model has been developed based on Machine Learning (ML) capable of predicting the country of origin (United Kingdom vs United States) according to metagenomic data. The data were used for the training of a glmnet algorithm and a Random Forest algorithm. Both algorithms obtained similar results (0.698 and 0.672 in AUC, respectively). Furthermore, thanks to the application of a multivariate feature selection algorithm, eleven metagenomic genres highly correlated with the country of origin were obtained. An in-depth study of the variables used in each model is shown in the present work.
Analysis of EEG-EMG Coherence in Low Frequency Bands
Authors: Arunganesh Krishnamoorthy , Sivakumaran Natarajan , Kumaravel Shanmugasundaram , Karthick Pa
Published: May 2021

In this, study, an attempt is made to analyze the corticomuscular coupling of the brain and muscular system in the low-frequency components during ramp descent (RD) and stair descent (SD) locomotion. For this purpose, magnitude squared coherence (MSC) is computed from the simultaneous EEG and EMG signals recorded during the ramp and stair descent tasks. The MSC is extracted from the low- frequency bands such as delta (0.1–3 Hz) and theta bands (4–7 Hz). The study utilizes a publicly available database consisting of simultaneous recorded EEG, lower limb EMG and full body motion information from ten healthy subjects. The results show that there exists corticomuscular coupling between motor cortex (C1, C2 and Cz contacts) and tibialis anterior muscle activities during RD and SD. In addition, the MSC differs for both the tasks and frequency bands. In delta band frequencies, the MSC is found to be higher in C2 regions. In the case of theta, the MSC is higher in C1 during RD and in Cz during SD. Therefore, the MSC associated with the low frequency components could be used to detect walking intentions.
Simulation of the Impact on the Workload of the Enlargement of the Clinical Staff of a Specialistic Reference Center
Authors: Giordano Noemi , Rosati Samanta , Valeri Federica , Borchiellini Alessandra , Balestra Gabriella
Published: May 2021

Quality of care and patient satisfaction are important aspects of high standard care. If clinical staff is subject to an elevated workload there is a possible decrease of both. This justifies the development of tools to quantify the workload and to find organizational changes that will normalize it. We have previously developed a simulation system to quantify the workload of the staff working in a regional reference center for the treatment of bleeding and hemorrhagic disorders. The goal of this new work is to simulate, through an agent-based model, the impact of adding a physician to the staff. Ten sets of initial parameters were defined to simulate ten typical weeks. Results show that the introduction of the new physician together with a second ambulatory room can reduce the workload of all the staff to the expected 8-hour. In this situation, in which the staff workload does not exceed the daily capacity, we may suppose that an increase in the quality of care and patient satisfaction will be possible.
What Characterizes Safety of Ambient Assisted Living Technologies?
Authors: Denecke Kerstin
Published: May 2021

Ambient assisted living (AAL) technologies aim at increasing an individual’s safety at home by early recognizing risks or events that might otherwise harm the individual. A clear definition of safety in the context of AAL is still missing and facets of safety still have to be shaped. The objective of this paper is to characterize the facets of AAL-related safety, to identify opportunities and challenges of AAL regarding safety and to identify open research issues in this context. Papers reporting aspects of AAL-related safety were selected in a literature search. Out of 395 citations retrieved, 28 studies were included in the current review. Two main facets of safety were identified: user safety and system safety. System safety concerns an AAL system’s reliability, correctness and data quality. User safety reflects impact on physical and mental health of an individual. Privacy, data safety and security issues, sensor quality and integration of sensor data, as well as technical failures of sensors and systems are reported challenges. To conclude, there is a research gap regarding methods and metrics for measuring user and system safety in the context of AAL technologies.
Harmonization of Finnish Vaccination Data
Authors: Vuokko Riikka , Vakkuri Anne , Palojoki Sari
Published: May 2021

Vaccination information is needed at individual and at population levels, as it is an important part of public health measures. In Finland, a vaccination data structure has been developed for centralized information services that include patient access to information. Harmonization of data with national vaccination registry is ongoing. New requirements for vaccination certificates have emerged because of COVID-19 pandemic. We explore, what is the readiness of Finnish development of vaccination data structures and what can be learned from Finnish harmonization efforts in order to accomplish required level of interoperability.
Use and Users of the Web-Based Omaolo Covid-19 Symptom Self-Assesment Tool in Finland Since March 16, 2020
Authors: Jormanainen Vesa , Soininen Leena
Published: May 2021

In Finland, it is possible to quickly produce medical symptom self-assessment tools within the existing infrastructure. The Finnish Omaolo Covid-19 web-based symptom self-assessment tool (symptom checker) was launched on March 16, 2020 after a 6-day development period. By using the web-based Omaolo Covid-19 symptom checker during the second wave of the epidemic, some 1.72 million questionnaires were recorded, out of which 1.55 million from symptomatic persons. Some 15% of the responses (245,500) were directed to seek emergency medical care based on the online screening by respondent response profiles.