bluuebunny/crossref_metadata_2025 huggingface dataset:
HOBİ, OYUN, SPOR VE E-SPOR ÜZERİNE ELEŞTİREL BİR DEĞERLENDİRME
Authors: ŞENSES Mihriban
Published: July 2020

Bu makalede hobi, oyun, spor, e-spor ve bilim kavramlarından hareketle gündelik hayatta hobiyi algılama tarzımız, oyunun tanımı, kapsamı ve içeriğindeki dönüşüm, geleneksel oyunlar, modern oyunlar ile dijital oyunlar arasındaki farklılıklar ve oyun, spor ile bilim arasındaki ilişki genel hatlarıyla ele alınmaktadır. Günümüzdeki hobi olarak tanımladığımız bazı aktivitelere fazlasıyla zaman ayırıyoruz. Özellikle ergen ve genç erişkin kesim bugün, mesleki bir boyutu olmadığında hobi olarak değerlendirilebilecek dijital oyunlara giderek bağımlı hale gelmektedir. Buna bağlı olarak günümüzde bu oyunların e-spor olarak tanımlanıp tanımlanamayacağı da önemli tartışma konularından birini oluşturmaktadır. Bu nedenle elinizdeki çalışmada öncelikle oyun tanımlarından hareketle günümüzdeki oyunların geçmiş veya geleneksel toplumlardaki oyunlardan hangi ölçüde farklılaştığı ve bu oyunların spor kategorisinde ele alınıp alınamayacağı tartışılmaktadır. Sonuç olarak oyunu algılama tarzımızda ve oyunun niteliğinde büyük değişikliklerin gerçekleştiği, dijital oyunların spor olarak değerlendirilmesinin aynı zamanda bu oyunları oynayan hemen herkesi sporcuya dönüştüreceği, birçok oyunun spor olarak değerlendirilmesinin ve sporun spor bilimleri başlığı altında bilimselleştirilmeye çalışılmasının büyük ölçüde tartışmalı olduğu ileri sürülmektedir.
Formulation and In Vivo Evaluation of Ticagrelor Self-nanoemulsifying Drug Delivery Systems
Authors: Aparna Adella , Kumar Yamsani Shravan , Bhikshapathi Darna V.R.N.
Published: July 2020

Background:

Ticagrelor (TGR), being an antiplatelet agent, belongs to BCS class IV
drug with low solubility and permeability that undergoes first-pass metabolism, leading to reduced
bioavailability of 36%.

Objective:

The main objective of this study is to develop TGR SNEDDS for enhancing solubility
and oral bioavailability.

Methods:

An oil, surfactant and co-surfactant (miglyol 810, brij 35 and lauro glycol FCC) are chosen
based on the maximum solubility of TGR. The selected vehicles are mixed in different ratios
and are agitated mildly. Transmittance values that are more than 80 were noted and are used for
constructing pseudo ternary phase diagram. Formulations that passed stability testing were evaluated
for % transmission, drug content and in vitro drug release analysis. In vivo bioavailability
studies of optimized SNEDDS are performed in Wistar rats.

Results:

From evaluation studies of TGR, formulation F13 with maximum drug release of 98.99%
in 60 minutes, that is higher than 31.99% of the pure drug is considered as an optimised formulation.
The particle size, Z average and zeta potential of the optimized TGR formulation F13 was
289.6 nm, 185.1 nm and -18.3 mV respectively. The FTIR and SEM studies do not indicate any
drug excipient interaction and confirm nano size which is stable for 3 months. From in vivo bioavailability
studies in rats, the Cmax of optimized TGR SNEDDS (302.43±4.78 ng/ml) is higher than
pure TGR suspension (47.32±2.75 ng/ml) and optimized SNEDDS exhibited 5 folds increase in
oral bioavailability when compared to pure drug.

Conclusion:

Hence the results reveal that, application of SNEDDS formulation technique for TGR
Increases solubility and oral bioavailability.
What Characteristics of the Acetabular Defect Influence the Choice of the Acetabular Component During Revision Hip Arthroplasty?
Authors: Tikhilov R. M. , Dzhavadov A. A. , Kovalenko A. N. , Denisov A. O. , Demin A. S. , Vahramyan A. G. , Shubnyakov I. I.
Published: July 2020

The purposes of the retrospective cohort study were: 1) to determine the severity of defects in the acetabulum and the probable causes of their formation in patients who underwent revision hip arthroplasty (RHA), as well as an assessment of factors that exacerbate the severity of the defects; 2) identifying the proportion of severe defects in the overall structure of acetabular revisions and determining the effectiveness of using serial implants in comparison with individual constructions made by 3D printing; 3) the rationale for rational indications for the use of individual constructions.Materials and Methods. The structure and reasons for the formation of bone defects in the acetabulum were evaluated in 726 cases of revisions performed from 2004 to 2018. In addition, the results of revision operations in a group of patients with severe defects (type 3 according to Paprosky and pelvic discontinuity) were evaluated.Results. The most frequent cause of defect formation was iatrogenic (53.2%), and the share of severe defects was 39.5% (287 observations). A factor aggravating the severity of the defect is the lack of its limitation by the support bone. The results of RHA in patients with severe defects were assessed in 186 cases out of 287 (64.8%). In 73 (39.2%) cases, individual constructions were used, the average follow-up was 26 months. (from 12 to 50), and in 113 (60.8%) cases, serial implants were used, the average follow-up period was 62 months. (12 to 186). Individual constructions were more often implanted in patients with 3B acetabular defects (p0.05) and its uncontained defects (p0.001). The number of cases of aseptic loosening in the group of patients undergoing endoprosthetics using serial implants was greater than in the group of patients with individual constructions for the entire period (p0.05) and in the early stages of observation (p0.05).Conclusion. In case of RHA in patients with severe acetabular defects, individual implants, in comparison with serials, demonstrate better survival with an average follow-up of 26 months and due to design features, they can count on great long-term effectiveness. This study needs to be continued to increase follow-up.
THE COMPARATIVE STUDY BETWEEN THE EFFECT OF COVID-19 AND EARTHQUAKE DISASTER ON TOURISM ATTRACTION IN YOGYAKARTA
Authors: Prakoso Yohanes Meindra , Ramadhika Boris
Published: July 2020

COVID-19 and earthquake disaster both give effect in Tourism Attraction, then in this study will compare the difference impact between COVID-19 and earthquake disaster, especially in Yogyakarta. This study deals with the hospitality industry condition during Corona Virus Disease (COVID-19) and earthquake disaster in Yogyakarta 2006. This study is to seek an answer to these two research questions: 1. What is the effect of the COVID-19 virus on Tourism Attraction in Yogyakarta? 2. Is the impact of the COVID-19 virus on Tourism attractions in Yogyakarta has a more severe impact than an earthquake in 2006? From the results of this study, it was found that COVID-19 is more dangerous than earthquakes, particularly in the economy sector. The method used in this study is a descriptive qualitative method; the problem that can be investigated by qualitative descriptive research refers to quantitative studies, comparative studies (comparisons). The data to support this study was taken from journals, books, websites, government documents, and any other sources or articles.
Ramat Geri Kazanım Prosesinde Açığa Çıkan Cüruflardan Gravite Ayırması ile Altın Kazanımı
Authors: SABAH Eyüp , ORUÇ ŞAPÇI Filiz
Published: July 2020

Bu araştırmada, ramatlardan altın/gümüş elde etmek için uygulanan ramat geri kazanım prosesinde açığa çıkan cürufta hapsolan altının gravite ayırması ile uygun koşullarda geri kazanımı amaçlanmış, maliyetleri azaltmak ve değerli metallerin geri kazanımını en üst düzeye çıkarmak için yüksek tenörlü/verimli altın ön konsantresi üretiminin mümkün olup olmadığı araştırılmıştır. Gravite ayırması ile zenginleştirme çalışmalarında santrifüj esaslı Knelson konsantratörü kullanılmıştır. Au tenörü 7 g/t olan soda-boraks esaslı cürufun bileşiminde yüksek oranda Fe2O3 (%13,25) ve PbO (%11,38) olduğu, boyuta göre yapılan sınıflandırma sonucu altının -0,5 + 0,212 mm fraksiyonunda yoğunlaştığı (%34) belirlenmiştir. Knelson konsantratörünün işletme parametreleri (yıkama suyu basıncı, santrifüj kuvvet, besleme hızı, pülp katı oranı vs.) ile besleme malı tane boyutunun konsantre/artığın Au tenörü ve altın kazanma verimine etkisi incelenmiştir. Altın kazanma verimi ve artığa kaçan altın miktarları dikkate alındığında yıkama suyu basıncı, santrifüj kuvvet ve besleme hızının ayırma performansına etkisinin sınırlı olduğu, besleme tane boyutunun ise konsantre Au tenörü üzerinde etkili olduğu tespit edilmiştir. 7 g/t Au tenörüne sahip cüruftan en uygun şartlarda %72,4 verimle 16 g/t Au içeren bir konsantre (artığın Au tenörü: 3 g/t) elde edilmiştir. Altının fraksiyonel bazda en yüksek dağılım gösterdiği -0,212 mm boyutunda besleme malı ile çalışıldığında, konsantrenin Au tenörü kayda değer bir artış göstererek 30 g/ton'a ulaşmıştır.
PENGARUH KONVERGENSI IFRS TERHADAP RELEVANSI NILAI INFORMASI AKUNTANSI PERUSAHAAN PERBANKAN DI BURSA EFEK INDONESIA
Authors: Djara Dwily Marlitah
Published: July 2020

Penelitian ini bertujuan untuk menguji apakah konvergensi International Financial Reporting Standards (IFRS) mampu meningkatkan relevansi nilai informasi akuntansi melalui nilai buku ekuitas per lembar saham dan laba bersih per lembar saham. Populasi penelitian ini adalah perusahaan perbankan yang tercatat di Bursa Efek Indonesia (BEI) pada periode 2007-2016. Pengujian hipotesis menggunakan analisis regresi dummy untuk melihat pengaruh konvergensi IFRS. Hasil penelitian menunjukkan adanya pengaruh konvergensi IFRS terhadap relevansi nilai informasi akuntansi yang ditandai dengan kenaikan nilai buku ekuitas per lembar saham dan laba bersih per lembar saham.
Integral Calculus Learning Using Problem Based Learning Model Assisted by Hypermedia-Based E-Book
Authors: Awaludin Awaludin , Wibawa Basuki , Winarsih Murni
Published: July 2020

The focus of this study is the effectiveness of the Problem Based Learning (PBL) model assisted by hypermedia-based e-books on the results of integral calculus learning. The objectives of the study are (1) to describe the students’ learning outcomes of integral calculus which are taught through problem-based learning model with the help of a hypermedia-based e-book, and (2) to find out the effectiveness of the Problem Based Learning model with the help of a Hypermedia-Based e-book on integral calculus learning outcomes. This research employed an experiment with a posttest only control design. The study population was all students from the Department of Mathematics Education, Halu Oleo University in the 2017-2018 academic year. The study sample consisted of 60 students distributed equally in two classes namely the experimental class (30) and the control class (30). The Problem Based Learning model with the help of a hypermedia-based e-book was applied in the experimental class while the traditional learning model with the help of printed teaching materials was applied in the control class. The PBL learning model steps consist of (1) presenting contextual problems, (2) forming cooperative groups, (3) analyzing problems cooperatively, (4) presenting the results of group discussions, (5) reflections. Data were collected using the test of integral calculus learning. Then the data were analyzed descriptively and inferentially. The descriptive analysis included the mean value, variance, and standard deviation, while the inferential analysis included the data normality test, the data homogeneity test, and the average difference test. The results showed that the students' integral calculus learning outcomes taught with Problem Based Learning model was categorized well, and the PBL learning model effectively improved the integral calculus learning outcomes.
DEVELOPMENT OF TOURISM BUSINESS POTENTIAL THROUGH THE USE OF SMARTPHONES IN MARKET TOURISM WARNASARI VILLAGE DISTRICT OF BANDUNG
Authors: Muhamad Yusuf Yogi , Asri Fitrananda Charisma , Iqbal Mochamad , Abdullah Rahiem Vikry
Published: July 2020

This service aims to provide socialization on the use of smartphones as a means of promotion in the tourism potential of Warnasari Village tourism business operators, PangalenganDistrict, Bandung Regency. The tourism businesses managed by tourism businesses and Youth Organization in Warnasari Village are Situ Cileunca, Rafting, Cukul Sunrise Point and AgroTourism. Business operators have developed several types of tourism potential in the Warnasari Village with a target market for the lower middle class. But because of the growing demand from consumers in terms of the tourism sector, the target market wants to be changed to the upper middle class. The problem that is owned by partners is the lack of ability in terms of the use of smartphones such as photo editing, video editing and the use of social media. Community service activities using a contextual approach that is providing theoretical material first and followed by workshops directly editing photos and videos using a smartphone and uploading his work produced by partners. Then proceed with the method of briefing photo and video editing techniques, and the use of social media in marketing tourism potential in Pangalengan.
Optimalisasi Pemisahan Menggunakan Kecepatan dan Waktu Sentrifuge yang Berbeda pada Ekstraksi Pati Jagung Varietas Lokal Kabupaten Garut
Authors: Rosalinda S. , Nurjanah Sarifah , Saputra Rudi Adi , Bafdal Nurpilihan
Published: July 2020

Kabupaten Garut memiliki 42 Kecamatan. Rata rata setiap Kecamatan memproduksi jagung setiap tahunnya. Jagung selama ini hanya dimanfaatkan sebagai pakan ternak, pemanfaatan atau pengolahan biji jagung belum maksimal. Meningkatkan nilai tambah jagung, jagung dibuat menjadi pati. Pati adalah bahan dasar dalam industri pangan, industri farmasi, perekat pada pabrik kertas dan berkembang sebagai bahan perekat bagunan. Memenuhi standar industri dan meningkatkan nilai tambah perlu menganalisis kadar pati. Proses pemisahan adalah bagian proses yang sangat penting dalam ekstraksi pati. Penggunaan alat pemisah memberikan keuntungan dianatranya efisien terhadap waktu dan menghasilkan pati yang lebih murni. Penelitian ini bertujuan untuk menentukan kecepatan dan waktu pada alat pemisah sentrifuge untuk menghasilkan kadar pati yang optimal. Bahan baku penelitian ini adalah jagung dari kelompok tani Kampung Lempong Desa Sukaharja Kecamatan Banyuresmi. metode yang digunakan adalah desain eksprimen dengan pendekatan Respon Surface Method (RSM) tipe Central Composite Design (CCD). Hasil penelitian menyimpulkan bahwa kecepatan dan waktu sentrifuge memberikan pengaruh yang nyata. Model signifikan dengan p value < 0.05 dengan nilai kadar pati yang optimum pada kecepatan 3650 rpm dan waktu 35 menit.
Pengaruh Peningkatan Kapasitas Tahap Esterifikasi Minyak Kemiri Sunan (Reutalis trisperma) sebagai Bahan Baku Produksi Biodiesel
Authors: Saputra Eki Dwiyan , Nurjanah Sarifah , Haryono Haryono , Kramadibrata Ade Moetangad , Mardawati Efri , Daradjat Wahyu , Handarto Handarto , Herwanto Totok , Rosalinda S. , Saukat Muhammad , Prijatna Dedy
Published: July 2020

Ketergantungan terhadap bahan bakar fosil menjadi permasalahan utama yang sedang terjadi. Biodiesel merupakan energi terbarukan berasal dari minyak nabati yang dapat mengurangi ketergantungan pada bahan bakar fosil. Kemiri sunan (Reutalis trisperma) merupakan salah satu tanaman yang bisa digunakan menjadi bahan baku pembuatan biodiesel. Karena nilai FFA yang tinggi menyebabkan reaksi esterifikasi harus dilakukan. Penelitian ini bertujuan untuk mengetahui pengaruh peningkatan kapasitas terhadap mutu dan rendemen dari minyak kemiri sunan hasil esterifikasi. Metode penelitian yang digunakan adalah analisis deskriptif dengan pendekatan korelasi regresi dengan nilai determinan terbaik. Esterifikasi dilakukan dengan menggunakan lima perlakuan kapasitas yaitu A = 200 mL; B = 400 mL; C = 600 mL; D = 800 mL; dan E = 1000 mL. Parameter mutu yang diuji pada penelitian ini adalah rendemen, densitas, viskositas kinematik, bilangan asam dan FFA, kadar air, indeks bias, dan warna. Hasil penelitian menunjukan peningkatan kapasitas pada proses esterifikasi mempengaruhi mutu minyak. Perlakuan E merupakan hasil terbaik yang diperoleh, karena memiliki nilai terbaik pada 5 parameter dari 8 parameter keseluruhan. Perolehan nilai rendemen, bilangan asam, FFA, densitas, viskositas kinematik, indeks bias dan warna (oHUE) pada perlakuan E secara berturut adalah 82,04%, 2,9702 mg-KOH/g-minyak, 4,61%, 0,9486 g/cm3, 4,94 mm2/s, 0,9939%, 0,0008951, dan 87,47991 (Yellow Red).
THE INFLUENCE OF EMPOWERMENT, INTERPERSONAL COMMUNICATION AND JOB INVOLVEMENT TOWARD EMPLOYEE PERFORMANCE THROUGH WORK MOTIVATION
Authors: SILALAHI ELVIE MARIA , Sembiring Hendri Sembirinng
Published: July 2020

The research is to analyze the influence of empowerment, interpersonal communication job involvement, on performance employee’s performance, through work motivations. Sample in this research totaled 101 employee’s. Sampling techniques using census method with saturated sampling technique, so the whole population is used as a sample.Variable this research consisting  empowerment, interpesonal communication, job involvement, work motivation, employee’s performance. Data collection methods used were questionnaires. Analysis of the data used is multiple linear regression analysis and path analysis using SPSS 24. The results showed direct  influence on employee’s performance  indicates empowerment and job involvement are supported, but for interpesonal communication is not supported. The Results of research indirect effect on employee’s performance through work motivation showed empowerment dan job involvement are not supported, but interpersonal communication supported. This research is expected to be beneficial for PT. Leo Hupindo to improve employee performance. Keywords : Empowerment, Interpesonal Communication, Job involvement, Work                     Motivation,  Employee’s Performance
Metanephric adenoma of the right kidney: a challenging diagnosis in a 49-year-old female
Authors: Nikolina Stavrinou , Aikaterini Roidou , Georgia Mitropoulou , Georgios Liadakis , Provatas Ioannis
Published: July 2020

Background:

Metanephric adenoma of the kidney is a rare, usually solitary, and benign tumor of the kidney, predominately affecting female patients in the fifth or sixth decade of life. It is considered by some specialists to be the hyperdifferentiated benign end of the Wilm’s tumor spectrum.

Case presentation:

The case was a 49-year-old woman with abdominal pain, a palpable mass in the right abdomen, and mild hematuria, without any other symptoms or laboratory findings. An ultrasonography and computed tomography revealed a tumor in the upper pole of the right kidney with a diameter of 5.3 cm. There was no infiltration of the neighboring structures and tissues. The differential diagnosis included papillary renal cell carcinoma, adult Wilm’s tumor, and metanephric adenoma. A partial nephrectomy was followed. The histological examination of the tumor revealed relatively small unvarying basophilic epithelial cells with scant cytoplasm, uniform nuclei, and some areas with nuclear grooves, delicate chromatin, and indistinct nucleoli in a loose non-cellular stroma and developed in a tightly packed alveolar, tubular, and rarely papillary pattern. The mitotic rate was extremely low. Tumor cells were positive for paired box gene 8, cluster differentiation 57, and Wilm’s tumor 1 and negative for racemase, cytokeratin 7, and EMA. The cell proliferation rate Ki-67 was extremely low, and there was diffuse, strong cytoplasmic positivity for BRAF V600E staining. Based on morphology and immunohistochemistry, the diagnosis of metanephric adenoma was made.

Conclusion:

Although metanephric adenomas may be difficult to diagnose clinically, the histological examination and the immunohistochemistry assay, including BRAF V600 staining, can make a safe diagnosis, avoiding the administration of incorrect treatment.
TouIST: a Friendly Language for Propositional Logic and More
Authors: Fernandez Jorge , Gasquet Olivier , Herzig Andreas , Longin Dominique , Lorini Emiliano , Maris Frédéric , Régnier Pierre
Published: July 2020

This work deals with logical formalization and problem solving using automated solvers. We present the automatic translator TouIST that provides a simple language to generate logical formulas from a problem description. Our tool allows us to model many static or dynamic combinatorial problems and to benefit from the regular improvements of SAT, QBF or SMT solvers in order to solve these problems efficiently. In particular, we show how to use TouIST to solve different classes of planning tasks in Artificial Intelligence.
SiamBOMB: A Real-time AI-based System for Home-cage Animal Tracking, Segmentation and Behavioral Analysis
Authors: Chen Xi , Zhai Hao , Liu Danqian , Li Weifu , Ding Chaoyue , Xie Qiwei , Han Hua
Published: July 2020

Biologists often need to handle numerous video-based home-cage animal behavior analysis tasks that require massive workloads. Therefore, we develop an AI-based multi-species tracking and segmentation system, SiamBOMB, for real-time and automatic home-cage animal behavioral analysis. In this system, a background-enhanced Siamese-based network with replaceable modular design ensures the flexibility and generalizability of the system, and a user-friendly interface makes it convenient to use for biologists. This real-time AI system will effectively reduce the burden on biologists.
Efektivitas Hatha Yoga Terhadap Kesehatan Fisik
Authors: Yusi Armini Ni Wayan , Diah Larashanti Ida Ayu
Published: July 2020

Today, humans are faced with life problems that are so tight with competition and competition in various aspects, so that it gives birth to a high tension culture. Tension that occurs causes disrupted anatomy of the body, even damage that causes balance of body and mind problems. This disharmony is a disease that many people face, namely stress, a psychosomatic disorder that can only be cured through inward healing, namely relaxation. Yoga is a method of self-discipline that has been applied and yoga also hits sports today, a sport that is very easy to use and at any time can and does not require a lot of space. So that yoga is made a healthy lifestyle trend that is not only recognized in the eastern hemisphere, especially for Hindus but also in the western world, which shows the universality of the teachings of Yoga itself that can be applied by anyone. One type of yoga that is famous in the world is Hatha Yoga. Hatha Yoga is one way of connecting with Iswara (God Almighty) by forming perfect harmony between the two pranic streams found in the body through the practice of Asana, Pranayama, Mudra and Bandha. So that Hatha Yoga is able to provide relaxation to the body and mind that will create physical and spiritual health.
Ajaran Karmaphala menurut Susastra Hindu Perspektif dalam Kehisupan Sehari-Hari
Authors: Subrata I Nyoman
Published: July 2020

The essence of Karmaphala teaches that there are three types of karma that are: karma that gives direct consequence, karma that has an indirect effect in which the reward is only enjoyed after death and the karma that will enjoy as a result of previous acts of life.

The Hindus seyoganya understand this universal karmaphala law. Understanding that, every Hindu believer will always think long to do something, since the consequence is in line with the nature of the act to be done. Because knowing the consequences of bad actions will bring bad consequences for himself, then people will abuse themselves from bad actions. That’s why they always do good deeds, because by doing good, the consequences will be fine
Whatever is done by human beings brings consequences, consequently there is good and bad quality, good results give pleasure and bad consequences to bring trouble. By doing so one must do good because everyone wants pleasure and live peacefully. The fruit of the act (karma) is called reward. The fruits of the act are not always directly perceived or enjoyed. Every act of leaving the former. There is a real container and there is an unidentified former (in the imagination and abstract) used carmavasana
Konsep Feminisme Gayatri Chakrasvorty Spivak dan Upaya Membangun Keluarga Unggul (Kajian Feminisme Modern)
Authors: Yunairi Dewi
Published: July 2020

Concept understanding is very necessary in various things as well as understanding about balancing roles in a family, it needs the understanding of feminism concept. The concept which initiated by Gayatri Chakrasvorty Spivak becomes a reference, as the identity of women in post-colonial feminism is understood as an awareness of women's differences. Third world women are considered to have a greater burden of oppression than first world women. The burden is based on colonial and imperial oppression of gender, race, ethnicity and religion, so that women's identity in postcolonial feminism is directed at a more productive domain to understand identity based on nationality awareness. Gayatri Chakrasvorty Spivak as one of the postcolonial theorists carefully sees that sexual oppression directed at third world women is an oppression that leads to subaltern sovereignty. Therefore, a transformation of subaltern women's awareness is needed by understanding the differences in women's experiences as the basis that woman empowerment is important to be able to form women who are more active and productive, and contribute positively to their families and communities. Overcoming subaltern in families who have a patriarchal tradition is certainly not easy, many things and efforts must be carried out. Providing space and opportunities for women is one of the efforts to uphold justice for women to take roles. Efforts to make a superior family can not be separated from the role of women. The existence of cooperation between parts of the family becomes the perfection and excellence of a family.
Interpretasi Terhadap Sloka 40 Kitab Sarasamuscaya Tentang Visi Misi Pandita Masa Depan
Authors: Girinata I Made
Published: July 2020

Pandita is someone who has gone through a dwijati or madiksa ceremony. Pandita duty is very important and absolute in Hinduism which even though it is difficult but Pandita duty is very noble and has moral obligations. In the face of increasingly complex developments, pandita should have credible abilities so they can compete with other religions. As the most important thing Pandita must still be able to maintain the value of her holiness by practicing the swadharma of dignity. Likewise, the community members, besides demanding that the purity of sulinggih be always maintained, should also be able to guarantee the lives and rights of Pandita / Sulinggih.
Nilai Filosofis Tata Ruang Bangunan Tradisional Bali dalam Teks Asta Kosala Kosali
Authors: Sari Ni Luh Komang Indah , Kusuma I Made Wirahadi
Published: July 2020

The concept of Balinese Architecture in the arrangement of the spatial value of traditional Balinese buildings which includes in the Asta Kosala Kosali text, provides the spatial design and layout of the building so that it has a philosophical value at the position of certain buildings. Structuring the building is supported by the concept of Tri Angga, Tri Mandala and lontar Asta Bhumi which can be in harmony between one building with another. The structure of this building can be seen from the shape of Padma Bhuwana which regulates the direction and symbol of the building. This can be influenced by values / spirituality, conditions / potentials owned, and economic commodities owned in the area that will be built.
KESADARAN HUKUM MASYARAKAT TERHADAP KEPEMILIKAN AKTA PERKAWINAN BERDASARKAN UNDANG-UNDANG NO. 1 TAHUN 1974 (STUDI PADA MASYARAKAT DI BANJAR PASTI)
Authors: Laksmi Danyathi Ayu Putu
Published: July 2020

Indonesia as a State of Law, has some rules about marriage that is Law Number 1 Year 1974. Marriage is legitimate if it is  according to the laws  of their  each  religion  and  belief. Furthermore, there is also an obligation to register their marriage. Pasti is the name of a banjar that located in Pandak Gede Village, Kediri District, Tabanan Regency, Province of Bali. To prove that the marriage existed, Pasti’s citizens must have a Marriage Act. This  research  aims to  determine the level  of community legal  awareness in Banjar Pasti on marriage certificate ownership, and to know and examine the factors that affect it. This research uses empirical juridical approach method, that is using the existing factual approach by way of observation and research in the field, then studied and reviewed based on relevant legislation as a reference to solve the problem. Based on the research, it is found that the level of community legal awareness in Banjar Pasti on marriage certificate ownership based on Law Number 1 Year 1974 regarding Marriage is relatively high. This can be proved by the following indicators : (a). The high level of community law knowledge in Banjar Pasti on marriage certificate ownership. (b). The high level of community law  understanding in Banjar Pasti  on marriage certificate ownership.  (c). The  high level of community legal attitude in Banjar Pasti on marriage certificate ownership. (d). The high level of community legal behavior patterns in Banjar Pasti on marriage certificate ownership. The Factors influencing the  community legal  awareness in Banjar Pasti  on marriage  certificate ownership under Law Number 1 Year 1974 regarding Marriage, that is : Level of education, Age and Sex.
KONSEKUENSI YURIDIS PUTUSAN MAHKAMAH KONSTITUSI NOMOR 13/PUU-XV/2017 TERHADAP TENAGA KERJA YANG MEMILIKI IKATAN PERKAWINAN DENGAN SESAMA TENAGA KERJA DALAM SATU PERUSAHAAN
Authors: Trisnadiasa I Nyoman Agus , Tagel Dewa Putu
Published: July 2020

The Problems that emerged in a marriage in Indonesia, visible seen in arrangement marriage in tje workplace, each worker / laborers in one company will undertake ongoing marriage, some companies both by the governmenr, and private, establishes a clause that limits the right to undertake ongoing marriage between workers/laborers in one company. That the existence of a clause the termination of employment, so that constitutional court thought the regulation contraty contrary constitutional the art 28D paragraph 1 the contitution of 1945 that everyone is entitled to form family and to survive through marriage legitimate. Expected for
company follow the constitutional court decisions.
PERAN SERTA DESA ADAT DALAM PENGELOLAAN SAMPAH DI KOTA DENPASAR
Authors: Sudarma Putra Ida Bagus
Published: July 2020

Masalah sampah saat ini merupakan fenomena sosial yang perlu mendapat perhatian dari semua pihak, karena setiap manusia pasti memproduksi sampah. Pemerintah kota Denpasar, tampaknya sangat menyadari kondisi tersebut sehingga dipandang perlu adanya suatu sistem dan peran pengelolaan sampah
dari hulu yaitu pengelolaan yang dilakukan sedekat mungkin dengan sumbernya, hal ini dilakukan agar pengurangan, penanganan, dan penegakan hukum terhadap pengelolaan sampah dapat berjalan disatuan terkecil masyarakat secara desentralisasi. Oleh karena itu dibutuhkannya peran serta desa adat dalam pengelolaan sampah di kota Denpasar untuk melakukan pengawasan, pembinaan, dan penegakan hukum melalui pembentukan suatu aturan hukumnya sendiri berupa awig-awig atau perarem untuk mengatur hak dan kewajiban masyarakat (krama desa, krama tamiu, tamiu, serta badan usaha yang berada dalam wilayah desa adat tersebut). Berdasarkan latar belakang tersebut, maka permasalahan yang dibahas dalam penelitian ini sebagai berikut: 1) Bagaimana sistem pengelolaan sampah di kota Denpasar? dan 2) Bagaimana peran serta desa adat dalam pengelolaan sampah di kota Denpasar?.
Metode penelitian yang digunakan adalah jenis penelitian empiris, sifat penelitian bersifat deskriptif, bentuk data kualitatif dan kuantitatif, pengumpulan data menggunakan metode observasi, wawancara, studi kepustakaan, penentuan informan penelitian menggunakan teknik purposive sampling, instrument penelitian mengunakan pedoman wawancara dilengkapi dengan handphone, camera digital, pencatatan, dan dengan analisis data deskriptif kualitatif. Belum efektifnya peran serta desa adat dalam pengelolaan sampah di kota Denpasar karena 1) masih sedikitnya keberadaan fasilitas pengelolaan
sampah seperti swakelola sampah, TPST 3R, TPS 3R, dan Bank Sampah yang dimiliki dan berada dibawah pengelolaan desa adat, 2) Masih rendahnya kesadaran masyarakat untuk melakukan pengelolaan sampah dari ruang lingkup keluarga atau rumah tangga sendiri, 3) Belum semua desa adat yang ada di kota Denpasar memiliki aturan dalam bentuk awig-awig atau perarem yang secara khusus mengatur hak dan kewajiban masyarakat (krama desa, krama tamiu, tamiu, serta badan usaha yang berada dalam wilayah desa adat tersebut). , 4) Kurangnya pelaksanaan pengelolaan sampah yang diwujudkan melalui sosialisasi ke setiap banjar.
Fungsi dan Makna Lingga dalam Ajaran Agama Hindu
Authors: Suta I Made
Published: July 2020

Hinduism is a religion that has given birth to a very complex culture in the field of astronomy, agricultural science, philosophy and other sciences. Likewise from this culture gave birth to worship facilities in the form of ancient relics, one of which was Lingga. Lingga is a symbol of fertility offered by the Indus valley civilization which is mainly associated with Shiva worship. Lingga can mean the manifestation of Lord Shiva which is described as Phalus which is usually placed above Yoni who describes men and women (Lingga-Yoni). The problem examined in this paper is how the function and meaning of Linga according to Hinduism in Indonesia. To answer these problems, data collection methods are used; literature studies, documents and observations and assisted with Religion and Symbol theory. Based on data data, it can be seen that the Lingga function is a religious function, namely strengthening, stabilizing Srddha Bhakti Hindus, then the function of fertility is by worshiping Lord Shiva through the media Lingga to invoke fertility on agriculture. Besides that, through worship Lingga has religious significance and symbolic meaning because Lingga is viewed from the religion as a symbol of worship before Lord Shiva. Lingga is believed to have magical powers so that Hindus draw closer to the presence of Ida Sang Hyang Widhi through the Lingga worship media in religious ceremonies such as piodalan in the Kahyangan Tiga / Jagat Temple. Symbolic meaning is Lingga as the symbol of Purusa (Akasa) and earth (Yoni) symbol of Pradana
Strategi Komunikasi Forum Kerukunan Umat Beragama dalam Pembinaan Kerukunan Umat Lintas Agama di Kabupaten Mojokerto
Authors: Pradnyaningrat G.A.A Agustine Dwi , Sudiana I Gusti Ngurah , Laksana Utama Putu Kussa
Published: July 2020

This research is mainly discussing about the FKUB in Mojokerto Regency where many cross-religion disputes occur. Based on that fact, the problems discussed in this reserach are (1) How is the eksistence of FKUB playing a role in maintaining the cross-religion harmony in Mojokerto? (2) What is the impact given by the FKUB in maintaining the cross-religion harmony in Mojokerto? (3) What is the benefit of communication strategy developed by FKUB in maintaining the cross-religion harmony in Mojokerto?
The theories used in this reasearc are (1) the theory of existence by Soren Kierkegaard, (2) the theory of structural fungsional, (3) constructivist theory. This research is using several methods which are Qualitative method with phenomenological approach. The location of this research is Mojokerto Regency while the data used is qualitative data. The data source are primary and secondary data. The technique to determine the informan is purvosive sampling.
This research found that (1) The existence of FKUB in carried out dialog between the leaders of various religions create a guideline for each religion to create peace and harmony among them selves and with others. (2) The positive impact is the harmony between religion exist but the negative effect is the bad impression while making the majority as decision maker. (3) there are three benefits gained from the comunication strategy of FKUB which are the villagers become more harmonious especially those having various religions, for the local organization, its member can blend in without thinking about their differences and third for the government officers where they can do their duty without thinking about their differences. It can be said that FKUB is doing an excellent job.
Adaptive Evolution of Peptide Inhibitors for Mutating SARS-CoV-2
Authors: Vukovic Lela , Han Yanxiao , Chaturvedi Parth , Kral Petr
Published: July 2020

The SARS-CoV-2 virus is currently causing a worldwide pandemic with dramatic societal consequences for the humankind. In the last decades, disease outbreaks due to such zoonotic pathogens have appeared with an accelerated rate, which calls for an urgent development of

adaptive (smart) therapeutics. Here, we develop a computational strategy to adaptively evolve peptides that could selectively inhibit mutating S protein receptor binding domains (RBDs) of different SARS-CoV-2 viral strains from binding to their human host receptor, angiotensin-converting enzyme 2 (ACE2). Starting from suitable peptide templates, based on selected ACE2 segments (natural RBD binder), we gradually modify the templates by random mutations, while retaining those mutations that maximize their RBD-binding free energies. In this adaptive evolution, atomistic molecular dynamics simulations of the template-RBD complexes are iteratively perturbed by the peptide mutations, which are retained under favorable Monte Carlo decisions. The computational search will provide libraries

of optimized therapeutics capable of reducing the SARS-CoV-2 infection on a global scale.
Evaluation of some properties of recycled polymethylmethacrylate incorporated to the acrylic resin
Authors: Amrah Y. Al Jmmal  , Nada Z. Mohammed  , Amer A. Taqa
Published: July 2020

Many attempts have been made enhancing properties of PMMA denture base material. Adding fillers to PMMA was a commonly used method to improve physical and mechanical properties. To estimate the effects of incorporating recycled polymethylmethacrylate with a different percentage with conventional heat-cured acrylic resin on some properties of heat-cured denture base resin. The recycled polymethylmethacrylate (Chaini-HK G) particles dissolved at (5%,10%,15%) was added to heat-cured polymethylmethacrylate (Spofadental, Czech Republic) polymer and mixed with a ratio of 2:1 with the polymethylmethacrylate monomer. A total number of specimens were 80, which divided into three experimental groups (5%, 10%, 15%) and control group. Each group have 20specimens. The surface hardness, water sorption, solubility and residual monomer of test groups measured as well as compared to that of control groups. Fourier transform infrared spectroscopy test (FTIR) was done for three experimental and control group. This study shows a statistically significant difference at (p<0.01) in the hardness of recycled polymethylmethacrylate incorporate material (10 %,15%) groups when compared with a control group; while recycled polymethylmethacrylate incorporated (5%) group show no significant difference, group with 15% shows the highest Vickers hardness value. The mean values of water sorption test solubility test and residual monomer were decreased with the increase of incorporating a percentage of recycled polymethylmethacrylate as compared to the mean value of the control group. The incorporation of recycled polymethylmethacrylate to heat acrylic resin at different percentage improves some of its properties.
Teenage pregnancy. Prevalence and adverse outcomes in Baghdad city
Authors: Thikra N Abdulla  , Weqar Akram
Published: July 2020

Pregnancy at an early age of life is a major challenge. The consequences of this problem have an impact on the quality of life of the young mother and her family, and determines an important risk for her offspring. The son of a teenage mother has, in general, greater risks than that of a mother of more than 20 years. The aim of this study is to determine the prevalence and outcome of teenage pregnancy. A descriptive data base study was conducted at Al-Elwia Maternity Teaching hospital in the period from January 1, 2019 to the end of June 2019 within the age between 12 and 19 years old. The mean age of the mother was 17.4 ±1.5 years. The mean age of the father was 23.9 ± 5.7 years with (69.5%) with Vaginal delivery and most of the teenage pregnant women were primigravidas (80.3%) and major group of birth weight neonate was in between 2500-4000 gm. Aanemia was the most common complication (55.8%) then pregnancy induced hypertension PIH (18.3%).The admission of the neonate to the neonatal intensive care unit (40.0%) are higher than other complications. In conclusion, Prevalence of teenage pregnancy was (21.9%), with high complications for mothers and neonate.
Microfluidic based Platform for drug screening-A review
Authors: Kalpana Seelam  , Daisy Rani A
Published: July 2020

There is a lot of requirement to develop a preclinical rapid drug screening devices to treat the throat cancerous patients in effective manner. Very High cost models like animal based, 2d and 3d type models are static drug screening models and they are unable to mimic the human body dynamic condition. So microfluidic platform based drug screening devices will give predetermined and prominent result in rapid drug screening by mimic dynamic body conditions. Now it is required to review what are the developments from last five years in screening the drug for cancer. Recently research is going on microfluidic platforms to screen the efficacy of mixed drugs, drug tolerance, and drug susceptibility. So this study presents the review on what are the advancements in microfluidic platforms for rapid drug screening and for different cancer patients. This study also presents what are the different sensing methodologies of microfluidic devices exists to screen the drug for various cancerous tissues
Expression of Hepatitis B viral surface antigen (Pre S1) in E. coli
Authors: Shahad Basel Ismail  , Yaseen Ismael Mamoori  , Ibrahim Abdulla Ahmed
Published: July 2020

Hepatitis B is the most common liver diseases, which caused by hepatitis B virus (HBV) infection. There are around 257 million people around the world suffer from severe chronic hepatitis B infection. Therefore, it is necessary to develop a vaccine to prevent viral infection. PreS1 is one of the HBV envelope proteins that have been proved to be an effective vaccine. Accordingly, Viral DNA was purified from patients’ serums and amplified by PCR using specific primers. Amplicons of 324 bp bands of PreS1 was observed on gel electrophoresis. The PreS1 was cloned into pTXB21 plasmid to form the recombinant plasmid pTXB1_PreS1 and transformed into DH5α E. coli. Screening of transformants was done using Colony PCR and Sequencing. Alignment of 26 polypeptide sequences showed conservation of this region. The pTXB1_PreS1 was retransformed into T7 Express Competent E. coli and screened using colony PCR. The PreS1 was expressed as a recombinant protein fused to an intein tag with a molecular weight of ~ 39.5 kD. The PreS1 protein was purified by a single affinity chromatography step and after cleaved from intein tag by Dithiothreitol the obtained protein had a molecular weight of ~ 11.5 kD. Only one protein band was observed on the SDS-page gel. The PreS1 protein was successfully cloned and expressed in E. coli, which can be used as a vaccine against HBV.
Benzothiazole moieties and their derivatives as antimicrobial and antiviral agents: A mini-review
Authors: Manahil B Elamin  , Amani Abd Elrazig Salman Abd Elaziz  , Emad Mohamed Abdallah
Published: July 2020

Heterocyclic chemistry has provided an inexhaustible source of pharmaceutical molecules. Heterocyclic compounds such as benzothiazole moieties and its derivatives area substantial class of compounds in pharmaceutical chemistry and exhibited therapeutic capabilities, such as antitumor, anticancer, antioxidant, antidiabetic, antiviral, antimicrobial, antimalarial, anthelmintic and other activities. Besides, some antibiotics such as penicillin and cephalosporin have heterocyclic moiety. The growing prevalence of multi-drug resistant pathogens represents serious global concern,which requires the development of new antimicrobial drugs. Moreover, the emergence of pandemic SARSCoV-2 causing Covid-19 disease and all these health dilemmas urge the scientific community to examine the possible antimicrobial and antiviral capacities of some bioactive benzothiazole derivatives against these severe causative agents.This mini-review highlights some recent scientific literature on different benzothiazole molecules and their derivatives. It turns out that, there are numerous synthesized benzothiazole derivatives which exhibited different mode of actions against microorganisms or viruses and accordingly suggested them as an active candidate in the discovery of new antimicrobial or antiviral agents for clinical development. The recommended bioactive benzothiazole derivatives mentioned in the current study are mainly Schiff bases, azo dyes and metal complexes benzothiazole derivatives; the starting material for most of these derivatives are 2-aminobenzothiazole although careful pharmaceutical studies should be conducted to ensure the safety and efficacy of these bioactive synthesized molecules as an antimicrobial or antiviral drug in the future.
Pregabalin As A Premedicant To Attenuate Pressor Response In Patients Undergoing Laparoscopic Cholecystectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Authors: Sweety Agrawal  , Shubdha Bhagat  , Pratibha Deshmukh  , Amol Singham
Published: July 2020

The present study was done to evaluate the ability of oral pregabalin to attenuate the pressor response to airway instrumentation in patients undergoing laparoscopic cholecystectomy under general anesthesia. Sixty-four adult patients aged between 25-55 year of either gender belonging to ASA-1 or ASA2 physical status weighing 50-70 kg were enrolled in this study. Thirty-two patients each were randomized to group A, or group B. Patients in group A received tablet Pregabalin (150mg) and those in group B received placebo orally one hour before induction of anaesthesia. Heart rate, blood pressure, and sedation were assessed preoperatively before giving the tablets and after 30 minutes, and just before induction of anaesthesia. Intraoperative, pulse rate, mean arterial pressure, ECG in the lead II, SPO2 and ETCO2 were monitored. All the above parameters were noted during laryngoscopy and intubation, 3 minutes after CO2 insufflation, and then at every 10-minute interval till the end of surgery. These parameters were also recorded after extubating the patient. The Ramsay sedation scale was used to assess the sedation at the baseline, one hour after drug intake , one hour after extubation and 4 hour after surgery. Any adverse effects in the postoperative period were recorded. The result of our study shows that pre-emptive administration of oral pregabalin 150 mg significantly reduced the pressor response at the time of laryngoscopy and intubation, after CO2 insufflation and just after extubation. We conclude that oral pregabalin premedication is effective in successful attenuation of hemodynamic pressor response to laryngoscopy, intubation and pneumoperitoneum in patients undergoing laparoscopic cholecystectomy