bluuebunny/crossref_metadata_2025 huggingface dataset:
Eff ect of Different Laser Irradiation Parameters on the Viability of Bacillus Species
Authors: Naji Reem A , Mohseen Huda K , AL-Daher Russell I
Published: April 2023

The genus Bacillus is present everywhere in the environment, it has environmental, industrial, and medical signifi cance. This heterogeneous group of bacteria shares unique characteristics, one of these is the resistance to physical and chemical agents. Laser light is one of the most interesting physical agents with a wide range of applications in all scientifi c fi elds. It has the ability to alter bacterial growth by triggering inhibitory or stimulatory mechanisms. In this study, laser parameters were varied to evaluate the eff ect of each one on the viability of Bacillus species. CW or chopped (532 nm) laser light at diff erent irradiation periods were examined. Results showed that tested bacterial species’ response to green laser light varied. Bacterial viability was dropped with increasing chopping frequency and exposure time. In conclusion, high repetition rate and prolonged exposure time increase the lethal eff ects of this type of laser
Synthesis, Characterization and Preliminary Antimicrobial and Antiinfl ammatory Evaluation of New Ibuprofen Hydrazide Derivatives
Authors: Kamms Zainab D , Hadi Mohammed K
Published: April 2023

Non-steroidal anti-infl ammatory medicines (NSAIDs) are medicines that are distributed widely across the world due to their ability to reduce pain and infl ammation. In order to boost the drug’s effi cacy and reduce its harmful side eff ect like GIT ulcers and bleeding, a newly synthesized series of 25-(1-(4-isobutylphenyl) ethyl)-1,3,4-oxadiazole-2-thiol derivatives compounds (C, C 1-3) were prepared from the reaction of ibuprofen hydrazide with carbon disulfi de followed by reaction with various Aryl/ alkyl halide. All target compounds were tested for antimicrobial effi cacy against various strains of bacteria (G+ve, S. pyrogenes and S. aureus) and (G-ve, E. coli and 1Klebsiella pneumoniae). Additionally, fungus species (Candida albicans). Compound C showed good antimicrobial activity for both bacterial strains. At the same time, Compound C1 have the best ant-bacterial activity compared with other synthesized compounds for1 both (G+ve), and (G-ve) bacteria, and compound C3 was the most aff ected one as antifungal. The compound C2 was with lowest antimicrobial activity. All of the produced compounds were examined for their anti-infl ammatory activity using (egg-white generate edema) and the compounds (C, C1, C3) showed good effi cacy when compared to ibuprofen (stander) FTIR and 1H-NMR spectroscopy were used to analyze all of the fi nal products.
Quantitative Determination of Zileuton from Spiked Human Plasma Using Liquid-Liquid Extraction Followed by RP-HPLC and UV Analysis
Authors: Pradeep Karia P , Pandurang Ayre A , Baburao Bhagyawant P , Divakaran Nair D
Published: April 2023

A rapid, cost-eff ective and simple “RP-HPLC method with UV detection” was developed for the determination of zileuton from human plasma. The method involved spiking human plasma and validation. Phenacetin (internal standard) and zileuton samples were prepared using LLE in diethyl ether which was used as solvent for extraction. “HiQsil C18 column (250 mm*4.6 mm* 5 m) was used for separation with tetrahydrofuran: water (45:55, v/v) as mobile phase. The fl ow rate was set at 1-mL/min and UV detection was done at 230 nm. Zileuton showed excellent separation from the internal standard and no interference was observed in plasma samples. A linear calibration curve was obtained in the 500 to 10,000 ng/mL range. The relative error (RE) and relative standard deviation (RSD) were found to be less than 15% for both within the run and between the runs. At lower zileuton concentrations, “weighted least square regression with a weighting factor of 1/X was used to reduce the heteroscedastic eff ect”. Extraction effi ciency of LLE method was confi rmed by the recovery of zileuton from samples. The stability data showed that “zileuton was stable in human plasma for 6 hours at room temperature for 30 days at -20°C after freeze thaw cycles”.
Standardization and Evaluation of Herbal Antihypertensive Sarpagandha (Reserpine) Tablet Formulations
Authors: Mali Dipak P , Kamble Snehal P , Gaikwad Dinanath T , Wadkar Ganesh H , Bhutkar Mangesh A , Tamboli Firoj A , Pawar Vijaykumar T
Published: April 2023

The need for herbal medicines is rising day by day tremendously all over the world. Many pharma industries are nowadays directing their studies on herbal material for their probable therapeutic values. In various scientifi c journals, a growing volume of research publications relied upon plant-based drugs and formulations. Hypertension is an important chronic disorder in economically developed as well as developing countries. According to WHO guidelines, it is necessary to standardize the herbal products that reach patients. Hence, standardizing the herbal antihypertensive formulations is necessary to give safe and eff ective medicines to the patients and society. The herbal antihypertensive formulation was standardized according to Ayurvedic Pharmacopeia and WHO guidelines. Various parameters such as botanical, physicochemical, pharmacological and toxicological were studied. A pharmacological study was carried to screen the selected marketed formulations for hemolytic and antihypertensive activity. The study showed that all formulations pass most of the standardization parameters and can be recommended for human beings. The outcome of present study will support the process of regulatory agencies and help in maintaining the quality of herbal medicines.
An Investigation on the Release Rate from Tramadol HCl-Loaded Microspheres made Using Various Polymers
Authors: Bathe Ritesh , Mali Audumbar , Mali Sunayana , Pande Jitendra , Bathe Dipak
Published: April 2023

Tramadol, an opioid analgesic, is used to relieve mild to moderately severe pain. It initially binds to the opioid receptor, and then it lessens the reactivity of norepinephrine and serotonin. The polymers EC, HPMC K4M, and CAP were encapsulated using the emulsion solvent evaporation process, and formulation characterization was completed. The obtained microspheres were round and white. The phosphate buff er with a pH of 6.8 was used for the in vitro investigations of the microspheres, which were carried out for 8 hours at a temperature of 37????C and 100 rpm in a 900 mL USP basket-type dissolution rate test equipment. Formulation F3 entrapped the most medication, but Formulation F6 displayed a greater yield. The impact of the polymer’s type and composition on the medication release was evident. The tramadol hydrochloride microsphere’s regulated drug release results in increased plasma drug content as well as better-quality bioavailability
In-silico Docking and Toxicity Analysis of N-acetyl D- glucosamine with Antimicrobial Proteins- A Novel Targeting against Antimicrobial Resistance
Authors: Roja Pathakota , Kumar V Santhosh .
Published: April 2023

Nutraceuticals are popular health-promoting agents for various disease ailments such as food supplements, health promoters, etc. The rising antimicrobial resistance concerns are a serious challenge to researchers and need of the hour to be addressed by developing novel antimicrobial agents. One prospective nutraceutical that has been chosen as a candidate for development as an antibacterial agent is N-acetyl-D-glucosamine. GlcNAc is a monomer of chitin, a substance found in the cell walls of several fungi, mollusks, and cephalopod beaks. The present study aimed to evaluate NAG’s antimicrobial potential by in-silico docking using Molegro virtual docker MVD 2013.6.0 as a novel approach. N-acetyl-D-glucosamine was tested against various targets like penicillin-binding protein (PDB3UDI) ligase (PDB2zdq), isomerase/isomerase inhibitor (PDB3TTZ), transferase (PDB2VEG), thymidylate kinase (PDB5UIV), dihydrofolate reductase (PDB3SRW), rifampicin-resistant, RNA polymerase (PDB6VVT) in diff erent confi rmations. Based on the docking scores obtained NAG was found to have potent activity against Acinetobacter baumannii, Thermus thermophilus, Staphylococcus aureus, Streptococcus pneumoniae, Salmonella typhi, Mycobacterium smegmatis, Candida albicans proving the therapeutic approach that can develop the NAG as antimicrobial agent. The toxicity analysis was performed using TEST software using diff erent methods proving there no report of endotoxicity of GlcNAc molecule that tend to be promising for developing the GlcNAc as lead for antimicrobial resistance. The future lies in evaluating the in-vivo antimicrobial potential studies of NAG.
Analytical Method Development and Validation for the Spectrophotometric Estimation of Hipuuric Acid Prodrug (Methenamine Hippurate)
Authors: Patel Vaishali , Patel Mansi , Velhal Niralee , Parmar Kinjal , Patel Janki
Published: April 2023

Hippuric acid, pronounced as n-benzoyl glycine, is utilized in the study of nutrition, small bioactive molecules, amino acid derivatives, peptide synthesis, chemical synthesis, cell biology, and chemical biology. It can be found in urine and is produced when glycine and benzoic acid combine. Treatment of urinary tract infections (UTIs) is challenging due to the development of resistant bacterial strains brought on by repeated use of antibiotics and chemotherapy. Methenamine hippurate as a pharmaceutical dosage form hasn’t been the subject of any published research, hence a UV-visible spectrophotometric analytical method development has to be created. Hippuric acid (10 g/mL) solution was made, and when it was scanned at 200–400 nm with distilled water as the green solvent, it was discovered that the maximum absorbance was at 228 nm. The linearity concentration range was found with an R2 = 0.998 correlation coeffi cient. The recovery experiment, which was conducted at three levels of 80, 100, and 120%, was used to evaluate the procedure’s accuracy. The recovery rate was discovered to be between 90 and 120%. The % RSD < 2 it proves that the method is Precise. The results confi rmed the approach’s high capacity to detect Hippuric acid and were consistent with industry standards. LoD and LoQ were discovered to be 0.169 and 0.048, respectively. This approach results in hipuuric acid in formulations
RP-UHPLC and HPTLC Method Development and Validation for Analysis of Andrographolide from Herbal Hepatoprotective Formulation
Authors: Ahmad Sufi yan , Mujawar Tabrej , Batewal Bhushan , More Priyanka , Gaikwad Asmita , Chumbhale Deshraj , Tare Harshal
Published: April 2023

This work aimed to create a speedy, precise, and selective HPTLC and RP-UHPLC method for analysing andrographolide in fi nished products and raw materials. Asian medicines are using Andrographis paniculata since long. It’s used to treat skin eruptions, boils, scabies, and chronic, unexplained fevers, all of which are caused by blood “abnormalities.” Liquid chromatographic methods were developed to separate andrographolide and its herbal dosage form. HPTLC chromatography employed a 10 by 10 cm aluminum plate coated with 0.2 mm of silica gel 60 F254 (E. Merck, Germany). Camag Linomat 5 applicator with 100 μL syringe was used to apply samples in 6 mm bands (Hamilton, Switzerland). 14 mm separated the two bands, and 150 nL sec-1 was applied. Mobile phase was dichloromethane, toluene, ethyl acetate, and formic acid (6:4:1:0.5). This chromatogram runs 80 mm. Camag TLC scanner measured density at 254 nm. Mean RF=0.69. The linear calibration curve covers 500–3000 ng/spot and has a 0.996 correlation coeffi cient. Limit of Detection: 31.5 ng; Limit of Quantitation: 95.48 ng. A validated RP-UHPLC method for quantifying andrographolide in extract and formulation has been established. UHPLC analysis was performed in isocratic mode, at room temperature, using acetonitrile: Water (0.2% acetic acid) (85:15, v/v) as mobile phase on a 250 mm 4.6 mm i.d., 5 μm Cosmosil C18 column. Detection was at 230 nm. Andrographolide has a 4.1 minute half-life. Between 10 and 60 g/mL, andrographolide was linear. The approach met or exceeded ICH’s linearity, precision, accuracy, and robustness
Identifi cation of Bioactive Niaziridin in Horseredish Tree Extract by Analytical Tool
Authors: Singh Chhaya , Saxena Rishi K , Tripathi Pawan
Published: April 2023

Moringa oleifera Lam. is mostly known as the „potent medicinal fl ora“ in terms of enormous therapeutic effi cacy due to the availability of certain biologically active molecules. This has dual characteristics: it can be used as food and an active ingredient in many pharmaceutical formulations. Flavonoids, phenols, and alkaloids are some of Moringa‘s most abundant bioactive compounds, and they are responsible for its signifi cant therapeutic properties. The current study is based on extracting and identifying major bioactive molecules from M. oleifera leaf and seed parts using a high-performance liquid chromatography technique to formalize its therapeutic potency of bioactive compounds. M. oleifera leaves and seed extracts in methanol were successfully analyzed in a single run using the HPLC method designed for this purpose. A Sunfi re C18 column measuring 4.6 x 250 mm was used for the 220 nm HPLC analysis, and the solvent system consisted of 0.1% acetate buff ered by acetonitrile (65:35 v/v) at a fl ow rate of 1.2 mL/min. The peak observed at 3.269 minutes in leaf extract and 3.289 minutes in seed extract shows the presence of niaziridin. The recovery values of niaziridin in M. oleifera leaves and seed extracts were 45.90 and 66.85%, respectively. Chromatograms show that seed extract has a larger amount of nitrile glycoside than leaf extract. The present investigation used an HPLC process to investigate the characteristics of niaziridin. This research is useful for standardizing M. oleifera leaf and seed extracts and producing pharmaceutical drugs from M. oleifera
Preparation, Characterization and Photocatalytic Degradation Studies of an Acrylic Acid-acryl Amide based TiO2 Hydrogel Nanocomposite: Real Samples of Pollutants Dyes
Authors: Hayder Noor A , Kadhim Ayat S , Aljeboree Aseel M , Dawood Farah A , Alkaim Ayad F , Alkaim Ayad F
Published: April 2023

In this study, preparation of (AAc-AM)/TiO2 hydrogel nanocomposite. This hydrogel was prepared by copolymerization. Acryl amide (AM), acrylic acid (AAc) is an absorbent material of great use in the preparation of hydrogels, Where hydrogels based on acrylate are characterized by being hydrophilic and having the ability to retain water. The properties of nanocomposite were studied using several techniques (FESEM, XRD, and TEM). The photocatalytic degradation of Congo red (CR) under UV irradiation has been studied. The utilization of (AAc-AM)/TiO2 hydrogel nanocomposite as a catalyst in the photocatalysis process under several optimum conditions. The eff ect of the parameter contains the mass of the (AAc-AM)/TiO2 hydrogel nanocomposite catalyst and the concentration of Congo red (CR). Through the data, the photocatalytic activity increases by increasing the hydrogel nanocomposite mass from 0.1–0.3 g. Also, a decrease in photocatalytic effi ciency was observed with an increase in dye concentration. Observed that after re-use, (AAc-g-AM)/TiO2 hydrogel nanocomposite paper photocatalytic effi ciency from of the 1 cycle use 77.99 to 60.12% of 6 cycle use repeated to show that (AAc-g-AM)/TiO2 hydrogel nanocomposite surface appear good stability.
Computational Investigation of the Impact of the Ghrelin Hormone Gene Variation (R51q) on the Hormone-receptor Binding Pattern
Authors: Adil Baraa , Shahar Saleha , Amran Syazwani I , Omar Mohd S S , Naser M Abu
Published: April 2023

Ghrelin is a peptide hormone made up of 28 amino acids. It is involved in various biological processes, including the stimulation of growth hormone release, control of food intake, and metabolic and cytoprotective eff ects. In 1999, this hormone was identifi ed as a ligand for the GHSR1a growth hormone secretagogue receptor. Ghrelin hormone-receptor complexes have been modeled in a few previous in-silico studies, but none of them have investigated the eff ects of the gene variation rs34911341/(R51Q) on the full-length ghrelin model and on the hormone-receptor binding. It was established that the full-length ghrelin model’s secondary structure was unaff ected by the R to Q amino acid substitution. Additionally, the mutant hormone-receptor complex exhibited better outcomes and altered the molecular interactions between the mutant ligand and the receptor by creating novel interactions, according to the post-molecular dynamic simulation analysis.
Cognitive mechanisms of naming medicinal plants in the Yakut language
Authors: ОСОРОВА М.А.
Published: April 2023

В статье анализируются особенности образования номинации фармакофитонимов в якутском языке. Целью данного исследования является выявление мотивационных признаков лекарственных фитонимов. В ходе исследования нами были рассмотрены номинации якутских лекарственных растений, такие как «эрбэhин», «ньээм», «бохсурҕан», «кулун кутуруга», извлеченные методом сплошной выборки из различных словарей и лексикографических источников. В ходе анализа были выявлены основные мотивационные признаки номинаций якутских названий лекарственных растений, например, «место произрастания растения», «внешний вид растения», «антропонимы в составе фитонимов», «метафорическая мотивированность» и др. Превалирующим мотивационным признаком при номинации названий лекарственных растений в якутском языке является «внешний вид растения», посредством чего образованы 21 фармакофитоним и с метафорической мотивированностью – 6 лекарственных названий растений. Также анализ показал, что в якутском языке превалируют двухкомпонентные и трёхкомпонентные конструкции фитонимов.

The article analyzes the peculiarities of pharmacophytonyms’ naming in the Yakut language. The purpose of this study is to identify motivational features of medicinal phytonyms. During the study we examined names of Yakut medicinal plants, such as “erbehin”, “n’eem”, “bokhsurghan”, “kulun kuturuga”, extracted by the method of continuous sampling from various dictionaries and lexicographic sources. The analysis revealed the main motivational features of Yakut names of medicinal plants, such as “place of plant growth”, “appearance of a plant”, “anthroponyms in phytonyms”, “metaphorical motivation”, etc. The predominant motivational feature in the names of medicinal plants of the Yakut language is the “appearance of the plant”, through which 21 pharmacophytonyms and six medicinal plant names with metaphorical motivation were formed. In addition, the analysis showed that in the Yakut language two-component and three-component phytonymic constructions prevail.
CATCALLING PHENOMENON AS A FORM OF SEXUAL HARASSMENT VERBALLY AGAINST WOMEN IN MALANG EMMANUEL LEVINAS FACE PHILOSOPHY PERSPECTIVE
Authors: Kwirinus Dismas , Pandor Pius
Published: April 2023

This research aims to explain the phenomenon of catcalling as a form of verbal sexual harassment against women in Malang from the perspective of Emmanuel Levinas' facial philosophy. This catcalling terminology emerged from several large urban areas in Indonesia, such as Jakarta, Malang, Yogyakarta and Surabaya. Catcalling is called verbal sexual harassment because the perpetrator responds to the victim, such as whistling, sexually nuanced remarks in the form of words that make the victim uncomfortable, feel humiliated and attack the victim's sexual attributes. Among urban communities, the term catcalling has a vague meaning because it is a joke or joke to victims, most of whom are women. This paper aims to describe, analyze and find out the form of communication from catcalling. The author uses a phenomenological analysis methodology. The type of research used is qualitative research methods: a critical reading of the text and observations. As for the findings in this study, they were catcalling, verbal sexual harassment and rape culture. For Levinas, the victim or woman who experiences catcalls is the other who is tortured and harmed.
ANALYSIS OF FACTORS CAUSING EARLY MARRIAGE FOR WOMEN IN PAMEUNGPEUK HAMLET, KADUDAMPIT DISTRICT, SUKABUMI REGENCY
Authors: Arifin Ali Zainal , Maulana Aris , Wuri Dewi Kartika , Fajrin Fahmy , Rahmawati Indriyani , Nada Katrin , Fadlyah Nada , Nurbus Nurkhayati , Napsiyah Siti
Published: April 2023

The problem of early marriage is one of the problems that is often found in Indonesia. However, this problem is more common in rural areas than in urban ones. Early marriage is a marriage that occurs between a pair of teenagers, both male and female, who are still not ready physically, physiologically, and psychologically. This study aims to analyze the factors that cause early marriage in Pameungpeuk Hamlet, Kadudampit District, Kabupaten Sukabumi. The method used in this research is a qualitative method with a literature study. To identify the location and informants in this study using a purposive sampling technique. Meanwhile, data collection techniques are in-depth interviews, observations, and case studies. The results of the study show that there are three (3) main factors that cause early marriage, including economic factors, educational factors, and parental factors.
THE SOCIAL NETWORK OF HOUSEHOLD INDUSTRY FOR KAREH-KAREH CAKES IN NAGARI KOTO LAWEH, X KOTO DISTRICT
Authors: Marnelly Tengku Romi , Forseta Olivia , Risdayati Risdayati , Resdati Resdati
Published: April 2023

This study describes social networks in the home industry of kareh-kareh cakes in Nagari Koto Laweh, X Koto District. The purpose of this study was to find out the form of the social network of the kareh-kareh household industry and how the social network functions in developing its business. Research using descriptive qualitative method. There were 10 informants, 6 of whom were supporting informants. Determination of informants using purposive sampling technique. Data collection techniques are by observation, interviews, and documentation. The theory used is the social network concept of Granovetter. The research results are as follows; The form of network that is created is that entrepreneurs have a micro social network, namely with fellow entrepreneurs, sellers of raw materials, cake craftsmen, and customers; meso networks of business actors, namely with the government, the Kharisma and Meekar capital groups, as well as with other parties such as universities and promotions on social media. There are norms and network density as well as efforts to maintain trust between actors so as to create a strong network. The function of the social network contained in the kareh-kareh cake home industry is as a lubricant, adhesive and bridge.
A STUDY OF MUSICAL STRUCTURE AND PANTUN TEXTS IN JONGGAN PERFORMING ARTS AMONG DAYAK KANAYATN
Authors: Olendo Yudhistira Oscar , Syam Christanto , Utama Indra
Published: April 2023

Jonggan is a popular performing art in the Kanayatn Dayak community in West Kalimantan. Jonggan performance art is a traditional art that the Dayak Kanayatn people have from generation own to generation. The Jonggan's performance is a blend of entertaining music, dance, and chanting rhymes. Along with the rapid development of technology, the function and role of musicians in the show have disappeared. The Jonggan art form that has been shown lately has changed characters, namely (1) dance movements, (2) costumes worn, (3) the presence of whistle-blowers, and (4) the presence of curtains. From the 1960s to 1970s, Jonggan art still existed. After that, from the 1980s until now, Jonggan's existence is almost unknown, especially among millennials, and even if it is shown, it has transformed. At this time, the term Jonggan was known as Jongset (Jonggan Kaset), meaning Jonggan, which was performed using cassette media (cassette = CD, DVD, or music files in Flashdisk); this eliminated the essence of traditional musical instruments. This reason raises the question, what is the structure of the accompaniment of rhymes in the form of melody and rhythm in the Jonggan performance art? The method in this research plan uses a descriptive method in a qualitative form with a musicological approach. The data can be seen directly from Jonggan's current existence. The research results on the structure of rhyme accompaniment music in the Jonggan performing arts are to maintain the preservation and understanding of material regarding traditional music so that it is better organized; Jonggan will become a performance industry based on culture and have an economic impact (creative economy). The musical structure in the Jonggan performing arts uses arguing, dau, gadobokng, and solving musical instruments.
Trend inflation and implications for the Phillips Curve
Authors: Hajdini Ina
Published: April 2023

This Economic Commentary estimates trend PCE inflation and a Phillips curve with time-varying parameters while allowing for trend inflation to affect the frequency at which firms change prices. Since the beginning of 2021, trend PCE inflation has risen well above the FOMC’s 2 percent long-term inflation target, and the most recent estimate of trend inflation in 2022:Q4 is 3.4 percent. With the increase in trend inflation, the Phillips curve slope has risen above its pre-pandemic level. At the same time, the relationship between current inflation and inflation expectations has strengthened. Together, these results imply that even though a slowing economy would help to bring down inflation through the steeper slope of the Phillips curve, high short-term inflation expectations could put upward pressure on inflation to a larger extent than they had prior to the pandemic.
Learning medical terminology in the process of integrated education of ukrainian as a foreign language
Authors: Kucherenko O.
Published: April 2023

The article explores important aspects of the use of integrated learning in studying Ukrainian as a foreign language, in particular the Ukrainian vocabulary of medical terminology.

Systematization and improvement of the terminological system in the created integrated courses of language disciplines will contribute to the successful mastery of medical terminology.

Integrated teaching of Ukrainian as a foreign language has the primary goal of developing a complete system of educational and methodological support for the entire period of study, taking into account, first of all, the specifics and directions of development of the specialty chosen by a foreign student.

The absolute educational requirements for the development of curricula and work programs and appropriate methodological support for each stage of language learning are consistency, correctness, systematicity and relevancy of the professional and language material, constant interdisciplinary coherence, and coordination, taking into account trends and features of rapid international development of medicine. Teaching Ukrainian as a foreign language should be aimed at careful thematic selection of textual and relevant terminological material for the best mastering of a certain professional discipline, taking into account the specific stage of study and this category of higher education. In the process of multifaceted interdisciplinary integration, it is extremely important to offer a dosed content terminological load for a foreign student in accordance with a specific stage of training in medical specialties. It is necessary to present a terminological material not only from simple to more complex but also taking into consideration system connections both at the level of the Ukrainian medical system of terms and that of modern interdisciplinary terminology.

Professional vocabulary developed in the classroom during the study must contain basic terms, relevant concepts, and definitions of these concepts with regard to Ukrainian and international standardized documents.

The relationship and coordination between professional and language disciplines in integrated learning are increased if the system of terms is understood and presented not just as a number of medical nominations but as an extremely dynamic logical and semantic unity.
Pedagogical grammar as the framework of tefl research. Part 12. Foreign language acquisition: mechanical memorization and overgeneralazation
Authors: Chernovaty L.
Published: April 2023

The paper presents the results of the analysis of experimental research data in this area. Over a long period of observation, the author studied two groups of subjects of different age categories with diverse social characteristics, using the oral interview as a way of obtaining research material. It was found that both mechanical memorization and overgeneralization are distinct features characteristic of the process of foreign language acquisition. Specifically, the manifestations of mechanical memorization were observed in the use of is not it (she, he, etc.) as a universal means to form disjunctive questions in sentences with can, have (got), going to, and is/are, as well as the simultaneous use of several of these verb forms; the use of what/where is as a universal question word; the use of I am instead of I or my; the use of going to or go to as one word; the use of it is as a universal formula and is as a universal operator to form general questions; simultaneous use of two operators, accompanied by the wrong word order, as well as the use of ‘empty’ forms. Overgeneralization was manifested in the use of are (is) as a universal operator, in particular in its simultaneous use with other operators (modal verbs, have (got) and do); use of articles with possessive pronouns, proper names, quantitative numerals, uncountable nouns or with countable nouns in the plural, or with other parts of speech (not nouns); the use of the long plural ending (-es) and the simple past tense (-ed) with already marked plural and past forms; the use of the -er marker to form the comparative degree of polysyllable adjectives; the use of the operator do in special questions to the subject; the double marking of the same grammatical feature, in particular the past tense, definiteness, negation, auxiliary verbs, and possessiveness. The author states that there is no reason to believe that the functioning of mechanical memorization and overgeneralization in the process of learning a foreign language is fundamentally different from the acquisition of the native language.
Polymorphism of the available potato gene pool for resistance to abiotic and biotic factors of the environment and its practical use
Authors: Bondus R. , Kharchenko Yu. , Furdyga M. , Mishchenko L. , Podhaietskyi A. , Hordienko V. , Hordienko O. , Koval V.
Published: April 2023

The article presents the results of 1954-2021 studies on the potato polymorphism as a consequence of species evolution and practical application of these investigations. The issue of adaptability of valuable genes of potato, which contributed to its preservation in nature for a long time, is covered, and the potato evolution is traced on living material. It is noted that some species of this crop do not exist any longer and, given this, the importance of the plant genetic bank as a depository of material and intellectual assets of the people of Ukraine is stressed. The studies allowed for identification of valuable potato accessions, analysis of the genealogy of individual cultivars, which provided an opportunity to investigate the relationships between modern cultivars and their ancestors. The identified or newly created valuable potato accessions found further practical use, as they were involved in breeding, scientific and educational programs. Due to multi-year research aimed at targeted involvement, effectively use and preservation of the authenticity of the valuable gene pool of potatoes as well as at optimization of the qualitative and quantitative composition of the National Bank of Plant Genetic Resources of Ukraine, a pedigree database on 301 accessions from 18 countries with certificates for 35 valuable unique accessions was formed and registered with the National Center for Plant Genetic Resources. We also built-up collections of 6 different types, specifically, a trait collection for yield including 46 accessions from 8 countries; a trait collection for starch content and technological scores (61 accessions from 5 countries); a working trait collection for large tubers (121 accessions from 16 countries); a working trait collection for resistance to viral diseases (31 accessions from 7 countries); and a trait collection for distinctness traits (568 accessions from 15 countries). The above collections and accessions of the potato gene pool are a concentrated reserve of valuable genes as well as material and an intellectual asset of the people of Ukraine; they play an important role in improving the welfare of the nation and the strength of the state, increase its scientific, intellectual and spiritual potentials and need preserving in a viable state and genetic integrity.
Regulation of the mitotic activity of root meristems and growth processes of soybean seedlings with a contrasting photoperiodic response by selective light
Authors: Batuieva Y. , Avksentieva O.
Published: April 2023

The present paper concerns the influence of selective light irradiation of various spectrums ‒ red (RL, 660 nm), green (GL, 530 nm), and blue (BL, 450 nm) on the proliferative activity of root meristem cells, biomass accumulation, and growth processes in the above-ground and underground parts of etiolated soybean seedlings. Seedlings of the soybean (Glycine max (L.) Merr.) of two varieties, contrasting in photoperiodic reaction, the short-day variety Khadzhibei and the photoperiodic-neutral variety Yatran, were used as plant material. Sterilized soybean seeds were germinated in Petri dishes for three days in darkness at 22±1°C. After that, their photoreceptor system was activated by irradiation with monochromatic light of red, green, and blue spectrums for five days, 30 minutes daily, with the use of Korobov LED matrices. Control plants were cultivated under the same conditions but without selective light exposure. Samples for the proliferative activity analysis were taken in dynamics on the 6th, 7th, and 8th days of the experiment. The seedlings’ growth reaction was analyzed at the end of the experiment, on the 11th day. The experiments showed that axial organs of soybean seedlings react in different ways when exposed to selective light of various spectrums: linear measures of the seedlings’ above-ground part largely depend on the RL impact, while the root system reacts more actively to the BL impact. Under activation of the phytochrome system with RL, the above-ground part of seedlings changes its morphogenetic development program from scotomorphogenesis to photomorphogenesis. At the same time, biomass accumulation in the etiolated seedlings of the short-day Khadzhibey variety was influenced by irradiation with all the applied spectra; the biomass of photoperiodic-neutral soybean seedlings of the Yatran variety was affected only by RL. The root meristem of etiolated soybean seedlings of the Khadzhibey variety was sensitive to both RL and BL irradiation, while that of the seedlings of the Yatran variety reacted to a greater extent to the BL and GL exposure. Based on the results obtained, we suppose that soybean seedlings with contrasting photoperiodic sensitivity have different compositions and activity of photoreceptor systems. It is manifested in regulation of the meristem proliferative activity, growth, and morphogenetic processes.
Aproximaciones culturales: una forma de ver y entender la naturaleza
Authors: Rosero-Toro Jeison Herley , Cerón Patío Angela María
Published: April 2023

Los seres humanos a lo largo de la historia han mantenido una estrecha relación con los recursos naturales, sin embargo, el uso y disfrute de los beneficios que se obtienen de los ecosistemas va a depender de diversos factores sociales, culturales, ambientales y económicos. De esta manera, los actores sociales son agentes cambiantes que incluyen variables culturales desde un enfoque socioecológico y etnobiológico y contienen diversas disciplinas y voces que deslumbran unas relaciones mucho más complejas entre la naturaleza y las comunidades. Por lo tanto, el presente libro, Aproximaciones culturales: una forma de ver y entender la naturaleza, se convierte en un insumo para el diálogo de saberes, en donde se presentan voces de comunidades rurales, urbanas, indígenas, docentes, investigadores y estudiantes de los distintos niveles académicos, conectando la Naturaleza desde distintos escenarios y posturas. Es así, como este proyecto editorial compila seis capítulos que tienen como base la relación entre los grupos humanos y su entorno, el diálogo de saberes tradicionales, y la importancia cultural y arqueológica. Por último, se resalta la participación de autores nacionales e internacionales, de distintas instituciones del sector privado y público, con aproximaciones y enfoques diversos que hacen de este libro un referente para la región huilense y el país.
Género, leña y salud: el caso de una comunidad rural en el estado de Jalisco, México
Authors: González Pedraza Kenia Marcela , Orozco Medina Martha Georgina , Figueroa Montaño Arturo , Noriega Moreira Miriam Sarahí
Published: April 2023

Los estudios a nivel mundial sobre calidad de aire de interiores y quema de leña utilizada por mujeres de zonas rurales para cocinar involucran la recopilación de informaciones distintas, y pueden ser clasificados en tres grandes grupos. El primer grupo establece una asociación directa entre el uso de biomasa y efectos en la salud (síntomas respiratorios, EPOC, asma, cataratas, alteración de la función pulmonar), sin entrar a detalle con el tipo de contaminante generado.
Ethnographic survey on cereal and pseudocereal in Bangladesh perspective
Authors: Rupa A.Z. , Rahim A.T.M.A.
Published: April 2023

Numerous studies have proven that cereal and pseudo cereal could be a great source of
polyphenols that help to prevent different lifestyle diseases like hyperlipidemia. The
ethnographic survey represents production, uses and consumption of cereal in Bangladesh
due to well-developed agronomy. On the other hand pseudo cereal (buckwheat, quinoa,
amaranth and chia) production, consumption and research actions are limited. This study
aimed to conduct an ethno-graphic survey of local cereals and pseudo grains will provide
the knowledge and current information of their availability and uses in Bangladesh for
advance research. A qualitative, inductive, exploratory and longitudinal study was
conducted. Bangladesh Institute of Development Studies (BIDS) and Bangladesh
integrated Household Survey (BIHS) investigated that people intake maximum 459 g and
33.5 g per capita rice and wheat in National level. Approximately 85% of black rice, 80%
of red rice and 99% of buckwheat were sold by local producers, identified by focus group
discussion. On the other hand 100% of experimental quinoa and chia production were
used for research purpose. Serious studies on Buckwheat, chia, millets, oat and sorghum
are conducting for their excellent nutritional value. The government of Bangladesh
conducted various developmental, agricultural, food and nutrition security programs
which indicate a positive social and political impact on the farming system. In spite of
having Governmental support, good agricultural practices, huge health and agro-economic
benefits, pseudo cereal production, distribution, use and consumption data are very scanty
in Bangladesh compared to other cereals.
Permanent education in maternal and child health for community health agents: an experience report
Authors: Santos Erlane Ribeiro dos , Gadelha Isabella Pereira , Soares Rita de Cássia Souza , Araújo Lorrane Teixeira , Amador Samuel Murilo Miranda , Albuquerque Waléria Beatriz Moura , Caldas Samantha Pereira
Published: April 2023

Objetivo: Relatar a experiência de acadêmicos de enfermagem na realização de uma atividade de educação permanente para Agentes Comunitários de Saúde sobre os cuidados à puérpera e ao recém-nascido. Métodos: Estudo descritivo, tipo relato de experiência, desenvolvido em uma Unidade de Saúde da Família de Belém-PA, nos meses de fevereiro e março de 2022, envolvendo os acadêmicos de enfermagem, a enfermeira da unidade e 10 Agentes Comunitários de Saúde (ACS). Para a construção e aplicação da atividade utilizou-se a metodologia da problematização através do Arco de Maguerez, representado em cinco etapas: observação da realidade, pontos-chave, teorização, hipóteses de solução e aplicação à realidade. Resultados: Os acadêmicos perceberam que os ACS demonstraram interesse nos assuntos abordados, e relacionaram os temas com as vivências na comunidade, bem como entenderam o papel fundamental que desempenham. Os assuntos observados maiores dúvidas e discussões foram: saúde mental da puérpera, cuidados com a higiene do recém-nascido e o calendário vacinal infantil. Conclusão: Através da experiência dos acadêmicos foi possível evidenciar que a educação permanente aos ACS sobre os cuidados da saúde da puérpera e do recém-nascidos é essencial para a qualidade do atendimento ofertado por eles à comunidade, contribuindo para uma assistência humanizada e individualizada.
PENGUATAN KELEMBAGAAN MANGROVE CENTER TUBAN (MCT)
Authors: Latifah Nurul Amirotul , Dwi Susilo Rachmad Kristiono
Published: April 2023

Tujuan penulisan ini adalah untuk mengetahui upaya dalam melakukan penguatan kelembagaan Mangrove Center Tuban. Penguatan kelembagaan yang dimaksud penulis meliputi pengelolaan administrasi dan juga birokrasi dalam persetujuan permohonan bibit. Pendekatan yang digunakan yaitu pendekatan siklus hidup (life cycle approach) dimana pendekatan ini memberikan pandangan mengenai stabilitas dan perubahan, sumber daya yang dibutuhkan, serta efektivitasnya dalam menjaga stabilitas dan menghadapi atau mengatasi sebuah perubahan. Pendekatan ini juga dapat memberikan motivasi dan optimisme kepada klien untuk memikul tanggung jawab yang lebih besar atas peristiwa dan situasi dalam kendali mereka. Organisasi memiliki siklus hidup dan tahapan perkembangan dalam organisasi kira-kira mendekati tahapan perkembangan dalam individu. Metode penelitian yang digunakan yaitu metode kualitatif PAR (Participatory Action Research). Teknik pengumpulan data melalui wawancara, observasi, dokumentasi dan negosiasi. Hasil penelitian menunjukkan bahwa (1) Penguatan kelembagaan Mangrove Center Tuban dapat dilakukan dengan memperbaiki pengelolaan administrasi terkait dengan pencatatan dan penyimpanan daftar tamu, daftar ijin tempat dan juga daftar permohonan bibit. (2) Melakukan pencatatan jumlah bibit guna mempercepat proses persetujuan permohonan bibit di Mangrove Center Tuban serta menghindari adanya kekeliruan.
Pendampingan Pengembangan Pembelajaran Seni Tari di SD
Authors: Darmayanti Mela , C.A Non Dwishiera , Nuryani Pupun , Heryanto Dwi , Hendriani Ani
Published: April 2023

Pembelajaran seni tari turut mengembang tugas dalam mencapai tujuan pendidikan nasional. Kegiatan dalam pembelajaran seni tari hakikatnya dapat mengembangkan kreativitas siswa, dan menjadi media pengekspresian diri dalam rangka mengembangkan kemampuan intelektual siswa. Peran pendidikan seni tari tersebut harus difahami oleh setiap guru SD, sehingga guru SD harus memiliki kesiapan dalam pembelajaran seni tari. Namun berdasarkan hasil kuisioner, 46% guru SD di Jawa Barat menyatakan kondisi pembelajaran seni tari yang dilakukan kurang optimal, karena guru kurang memahami model pembelajaran yang dapat mengembangkan kreativitas siswa melalui pembelajaran seni tari, terlebih di dalam kondisi pembelajaran jarak Jauh saat ini. Sebagai salah satu upaya dalam mengatasi permasalahan tersebut, maka tim PkM melaksanakan kegiatan PkM dengan metode workshop (pelatihan) dan pendampingan tentang model pembelajaran tari pendidikan serta pembuatan media digital dalam pembelajaran seni tari pada guru-guru SD di Jawa barat. Hasil kegiatan menunjukan, peserta pelatihan (guru) merasa sangat puas dengan kegiatan yang telah dilaksanakan, dan sebagian besar peserta pelatihan memahami materi terkait model pembelajaran tari pendidikan dan memahami pembuatan media digital untuk pembelajaran seni tari.
PENGUATAN KADER TUBERKULOSIS PUSKESMAS GULUK-GULUK KEBUPATEN SUMENEP
Authors: Sensusiati Anggraini , Rosyid Alfian , Puspitasari Arina
Published: April 2023

Tujuan dilaksanakannya kegiatan pengabdian masyarakat (pengmas) ini adalah untuk memberdayakan masyarakat, khususnya kader Tuberkulosis (TB). Dengan program ini diaharapkan agar kader TB mampu mendampingi pasien TB serta mengidentifikasi masyarakat suspek TB agar mereka mau memeriksakan diri ke Puskesmas dan menjalani pengobatan hingga sembuh. Waktu pengobatan yang lama, keengganan penderita TB untuk memeriksakan diri, ditambah dengan rasa takut akan didiagnosis sebagai penderita COVID menjadi beberapa alasan yang menyababkan banyak penderita dan suspek TB di Kabupaten Sumenep tidak tertangani dengan baik.

Salah satu upaya yang dapat dilakukan untuk menangani permasalah TB adalah dengan memberikan pendamping pada penderita TB, yang dalam kasus ini adalah dengan memberdayakan kader TB. Selain memberikan pendampingan pada penderita TB yang sudah terkonfirmasi kondisinya, kader juga berperan penting dalam mengidentifikasi mayarakat yang dicurigai menderita TB. Setelah berhasil mengidentifiaksi suspek TB, kader perlu untuk mendorong agar mereka mau memeriksakan diri dan menjalani pengobatan.

Melalui kegiatan pengmas ini kader diberikan materi dan dilatih melalui simulasi agar dapat memberikan pendampingan dengan baik. Pemberian materi diharapkan mampu memberi penyegaran dan menambah pengetahuan kader mengenai TB. Simulasi dilakukan agar kader dapat meningkatkan kemampuan mereka dalam melakukan pendampingan. Selain itu, diharapkan kegiatan ini dapat mendukung program pemerintah dalam upaya memberantas penyakit TB di Indonesia.
Bread Making Process from Banana Flour and Modified Cassava Flour in Silo Village, Jember
Authors: Sukoco Aji , Handayani Septy
Published: April 2023

Cassava and banana are the most agricultural commodities grown in Silo Village. Farmers plant these commodities as a response to local needs. In order to add more value to these commodities, the team of community service program strives to make a gluten-low bread by utilizing flours made from cassava (mocaf) and banana. This community service program was implemented to introduce bread made from mocaf and banana flours as alternative flours for wheat flour, as well as enhance skills and knowledge of the society in Silo village. The methods used in this community service program were participants approach and field observation, training program, and accompaniment of participants. The monitoring program was conducted during accompaniment of participants to check the progress established in the development objective. Modules were also provided by the team of community service program. The group of the Family Welfare Movement in Silo Village were interested during the training program due to the innovation presented. The gluten-low bread was processed by supplementing mocaf and banana flour to the dough. A combination of 70% of wheat flour, 20% of mocaf, and 10% of banana flour resulted in airy and soft bread, as well as delicious taste. As a consequence of gluten reduction in the raw materials, the amount of instant yeast and the length time of dough fermentation were increased twice compared to the common bread made from whole wheat flour. About 30% of wheat flour in the bread-making process could be substituted by the combination of 20% of mocaf and 10% of banana flour. The community service program could also be performed to improve the experience and skills of the group of Family Welfare Movement in Silo Village.