bluuebunny/crossref_metadata_2025 huggingface dataset:
Biologically Reduced Zinc Oxide Nanosheets Using Phyllanthus emblica Plant Extract for Antibacterial and Dye Degradation Studies
Authors: Khalid Awais , Ahmad Pervaiz , Uddin Khandaker Mayeen , Modafer Yosra , Almukhlifi Hanadi A. , Bazaid Abdulrahman S. , Aldarhami Abdu , Alanazi Abdulaziz M. , Jefri Ohoud A. , Uddin Md. Mohi , Qanash Husam
Published: April 2023

The nanostructures synthesized using the green chemistry method have recently attracted the attention of scientists due to their significance in many scientific domains. This work provides an overview of the biosynthesis of zinc oxide (ZnO) nanosheets (NSs) using Phyllanthus emblica plant (PEP) extract. X-ray diffraction analysis (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and Fourier transform infrared (FTIR) were used to analyze the synthesized ZnO-NSs. Evaluation of the antibacterial activity of biosynthesized ZnO-NSs was performed. ZnO-NSs exhibit effective antibacterial activity against Gram-positive (S. pyogenes and S. aureus) and Gram-negative (S. typhi and E. coli) bacterial strains. S. typhi is the most sensitive microbe towards ZnO-NSs and formed a 21 mm zone of inhibition (ZOI). ZnO-NSs are also tested as a photocatalyst in the degradation of methyl orange (MO) and rhodamine B (RB). The degradation rate of MO was 90%, and RB was 96% after being exposed to UV light for 120 min. The as-synthesized ZnO-NSs exhibited selective dye degradation and showed relatively better photocatalytic activity for positively charged (cationic) dyes. This work could lead to the fabrication of high-yield photocatalysts, which have the potential to degrade textile dyes from aqueous solution.
Polymethylmethacrylate-Based Nanocomposites for Denture Base Fabrication: Impact of Nanoparticle Type and Concentration on the Color Change In Vitro
Authors: Emam Abdel-Naser M. , Azmy Emad A. , Reda Zaki Al-kholy Mohamed , Gad Mohammed M. , Ahmed Helal Mohamed
Published: April 2023

Background. Although the mechanical behaviors of PMMA were improved with nanoparticles addition, there is a lack of study on the color changes of nanocomposite denture base resin. This study aimed to assess and compare the color of nanocomposite denture base resin modified with different nanoparticles and concentrations. Materials and Methods. Three nanoparticles (zirconium dioxide (ZNP), titanium dioxide (TNP), and silicon dioxide (SNP)) were added to heat-polymerized acrylic resin in 3 and 7 wt% concentrations. A total of 70 acrylic discs (20 × 2 ± 0.03 mm) specimens were prepared while one without addition (control) and three main groups according to nanoparticles and two subgroups according to % (3ZNP, 7ZNP, 3TNP, 7TNP, 3SNP, and 7SNP) with total 70 acrylic discs (n = 10). Spectrophotometer was used for color change (ΔEab) followed by value conversion to National Bureau of Standards units (NBS) to relate the color alterations (ΔEab) to the clinical environment which aids in determining a threshold for clinical acceptance of the color change. ΔEab data were analyzed and compared using one- and two-way ANOVA tests followed by Bonferroni’s post hoc test (α = 0.05). Results. Two-way ANOVA showed that filler type (regardless of filler concentration) had a statistically significant effect on mean ΔEab (

P
<
0.001

). Filler concentrations (regardless of filler type) showed a significant effect on mean ΔEab while the filler type and concentration interaction showed no significant effect on mean ΔEab (

P
<
0.001

). One-way ANOVA in terms of filler types results showed a significant difference between mean ΔEab (

P
<
0.001

), where TNP group showed the highest mean ΔEab followed by ZNP and SNP. Pair-wise comparison revealed that 3% concentration showed a significant lower mean ΔEab than 7% concentration (

P
<
0.001

). Conclusion. Modification of heat-polymerized denture base resin with ZNP, TNP, or SNP causes clinically unacceptable color change. TNP produced the highest color change followed by ZNP and SNP, and the color change is concentration dependent; the color change increases as the concentration increases.
Serum Levels of Proinflammatory Biomarkers in Military Recruits with and without Metabolic Syndrome
Authors: Al Asmari Abdulrahman K. , Al Shehri Hamoud A. , Khan Haseeb A. , Al Omani Saud , Kadasah Saeed G. , Horaib Ghaleb B. , Al Buraidi Ahmed , Al Sharif Abdullah A. , Mohammed Fayez S. , Abbasmanthiri Rajamohamed , Osman Nasreddien M.
Published: April 2023

Objectives. Inflammatory mediators are associated with many chronic diseases; however, their role in metabolic syndrome (Met-S) is not well documented. We therefore aimed to compare the serum markers of inflammation including C-reactive protein (CRP), myeloperoxidase (MPO), interleukin-6 (IL-6), tumour necrosis factor alpha (TNF-α), and TNF-β in young military recruits with and without Met-S. We hypothesized that any significant change in inflammatory markers between the two groups would indicate the role of inflammation in Met-S that would help in future directions for screening and treatment of Met-S. Design and Methods. A total of 2010 adult men, aged 18-30 years, were divided into two groups: with Met-S (

N
=
488

) and without Met-S (

N
=
1522

), according to the International Diabetes Federation definition. We compared the serum levels of inflammatory biomarkers between the two groups. We also studied the correlations between the inflammatory markers and the components of Met-S to explore the biomarker potential of inflammatory markers for screening of Met-S. Logistic regression analysis was performed to test the association between inflammatory markers and Met-S. Results. A large number of subjects in the Met-S group were suffering from obesity. Out of the 2010 total subjects, only 731 (36.4%) had normal fasting blood sugar (FBS), while the prevalence of prediabetes and diabetes was significantly higher in subjects with Met-S. We observed significant increases in serum levels of CRP, MPO, IL-6, and TNF-β but not TNF-α in subjects with Met-S as compared to subjects without Met-S. All the markers of inflammation showed significant correlations with Met-S, triglycerides (TG), blood pressure, body mass index (BMI), and age; however, none of these markers were correlated with HDL. Logistic regression analysis showed a significant association between Met-S and inflammatory markers. Conclusions. Serum levels of CRP, MPO, IL-6, and TNF-β are significantly increased in young adults with Met-S. This is probably the first study reporting TNF-β levels in Met-S. Since a proinflammatory cascade precedes many years before the onset of cardiovascular disease, these inflammatory biomarkers could help in the monitoring of high-risk individuals with Met-S who will be requiring therapeutic intervention.
Increased FOXM1 Expression was Associated with the Prognosis and the Recruitment of Neutrophils in Endometrial Cancer
Authors: Chen Jing , Yang Pusheng , Li Shaojing , Feng Yichen
Published: April 2023

Background. Although the biological functions of Forkhead box protein M1 (FOXM1) were explored in a variety of cancer, to date, however, little attention has been paid to the situation of FOXM1 in EC endometrial cancer (EC). Method. Bioinformatics analysis, including GEPIA, TIMER, cBioPortal, LinkedOmics, and STRING were used to analyze the FOXM1 gene expression, genetic alteration, and immune cell infiltration in EC. IHC staining, qPCR, cell viability, and migration assay were applied to identify the functions of FOXM1 in EC. Results. FOXM1 was highly expressed in EC tissues and closely correlated with the prognosis of EC patients. FOXM1 knockdown inhibited EC cell proliferation and invasion as well as migration. FOXM1 genetic alteration was verified in EC patients. Coexpression network of FOXM1 indicated that it had roles in the EC cell cycle and the infiltration of immune cells in EC. Furthermore, bioinformatic and immunohistochemical analysis indicated that FOXM1 induced the increased CD276 expression and also enhanced the neutrophil recruitment in EC. Conclusion. Our present study discovered a novel role of FOXM1 in EC, suggesting FOXM1 could be treated as a potential prognostic biomarker and immunotherapeutic target in EC diagnosis and treatment.
Study on the Seismic Response and Aseismic Measure of Fault-Crossing Tunnels under Combined Action of Fault Dislocation and Seismic Motions
Authors: Li Jieli , Ma Zhiguo , Li Ruohan , Cao Zhensheng , Zhang Shaoqiang
Published: April 2023

Seismic investigation revealed that a fault fracture zone is one of the most vulnerable areas of mountain tunnels in earthquakes. For the tunnel crossing secondary fault, the fault may be permanently dislocated by the causative faults during earthquakes, making the tunnel subject to combined action of seismic motion and fault dislocation, which makes the seismic response of the tunnel more complicated. In order to investigate the seismic response of fault-crossing tunnels in this case and explore the suitability of different aseismic measures, three-dimensional numerical models with different widths of faults and different aseismic measures were developed in this study. By inputting accelerogram considering permanent displacements, the seismic responses of fault-crossing tunnels under the combined action of seismic motion and fault dislocation were simulated. The results showed that the acceleration and stress of the tunnel-crossing narrow fault are larger than those crossing wide faults during earthquakes. Grouting reinforcement can reduce the acceleration and stress of the tunnel within the fault during earthquakes, while flexible joints will increase the acceleration of the tunnel within the fault and increase the stress of the tunnel-crossing wide fault. For fault-crossing tunnels, if the fault width is narrow than the tunnel diameter, the best aseismic measure installs grouting reinforcement and flexible joints; if the fault width is wider than 10 times of the tunnel diameter, the best aseismic measure installs grouting reinforcement.
Modelling and Design Optimization of a Novel Wide‐Body Transport Aircraft to Improve the Structural Integrity
Authors: Dhara Aishwarya , Jeyan J. V. Muruga Lal , Majumder Arunava
Published: April 2023

One of the most challenging next‐generation issues is examining a novel and sustainable aircraft to reduce emissions and fuel burn. IATA addressed these issues in collaboration with the EU, GARDEN, and Clean Sky programs to tackle the challenges using retrofit design and upgraded systems. This study aims to create a sustainable aircraft design to solve the fuel burn issue by minimizing the maximum take‐off weight (MTOW). An optimized wide‐body aircraft is established by selecting twelve aerodynamic design variables and fourteen flight mission constraints (retrofit, operational performance, and stability). To develop a sustainable wide body aircraft structure, this study proposes a hybrid design optimization algorithm combined with the multicriteria decision‐making (MCDM) technique. The CRITIC‐WASPAS technique is used to obtain the baseline aircraft, and the optimal design of the baseline aircraft is achieved by solving the proposed nonlinear constrained optimization model. The selected baseline aircraft was compared with the optimized result to validate and determine the robustness of the objective function. The findings reflect that the formulation has improved the MTOW, empty weight fraction, fuel weight, and performance by 3.75%, 28.38%, 2.06%, and 8.63%, respectively.
Relationships between Inflammatory Biomarkers and Fatigue among Patients with Moderate and Severe COVID-19
Authors: Gharaibeh Besher A. , Rababah Jehad , Haneyah Obieda
Published: April 2023

Background. Patients with moderate or severe COVID-19 infection suffer from varying levels of fatigue; however, there is a lack of understanding regarding the effect of inflammation on fatigue; and whether these relationships differ according to the severity of the infection. Aim. To assess the relationships between selected inflammatory biomarkers and fatigue levels among hospitalized Jordanian patients with moderate or severe COVID-19 infection. Methods. A quantitative cross-sectional design was used. A total of 352 participants were recruited for the study. Data regarding fatigue type and level were collected using the Chalder fatigue scale. Laboratory test results regarding several selected inflammatory biomarkers (e.g., ESR, CRP, IL-6, D-dimer, and others) were collected from patient records. The severity of the COVID-19 infection was determined using the criteria of the Ministry of Health in Jordan based on the results of O2% (oxygen saturation). Results. The mean scores of the total fatigue level significantly differed between the two levels of the severity of COVID-19 infection (moderate and severe levels) (t = −3.0,

p
<
0.05

). Similar findings were observed with physiological fatigue (t = −3.50,

p
<
0.05

), and no significant difference was observed in psychological fatigue. Out of the selected inflammatory markers, only neutrophil and lymphocyte count had a significant influence on total fatigue level. Conclusion. The level and type of fatigue was affected by the severity of the disease. However, the disease process itself represented by the levels of the inflammatory markers showed little influence on fatigue. The implications such as continuous screening of fatigue, and monitoring of the levels of the inflammatory markers are important to assist in diagnosing and managing COVID-19 patients. Furthermore, the relationship between the inflammatory process and fatigue is complex and requires further exploration.
Hyperspectral Image Restoration via a New Symmetric ADMM Approach
Authors: Wang Shuo , Zhu Zhibin , Zhao Ruwen , Zhang Benxin
Published: April 2023

For the hyperspectral image (HSI) denoising problem, a symmetric proximal alternating direction method multiplier (spADMM) is proposed to solve the sparse optimization problem which cannot be solved accurately by traditional ADMM. The proposed method finds a high‐quality recovery method using the traditional low‐rank Tucker decomposition method, which can fully take into account the overall spatial and spectral correlation between HSI bands by using the Tucker decomposition. By choosing appropriate steps to update the Lagrange multipliers twice, it makes the selection and use of variables more flexible and better for solving sparsity problems. To maintain stability, we also add appropriate proximity terms to solve the problem during the computation. Experiments have shown that the spADMM has better results than the traditional ADMM. The final experimental results on the dataset demonstrate the effectiveness of the method.
Copper-Doped Zinc Oxide Nanoparticles: Synthesis, Characterization, and Application for Adsorptive Removal of Toxic Azo Dye
Authors: Sowjanya Bandela , King Pulipati , Vangalapati Meena , Myneni Venkata Ratnam
Published: April 2023

The goal of this research was to employ copper-doped zinc oxide nanoparticles (Cu/ZnONPs) as an adsorbent to remove the potentially toxic azo dye Congo red (CR). The Cu/ZnONPs were made using a chemical coprecipitation method, and their characteristics were examined using XRD, SEM, EDS, and FTIR methods. The response surface methodology (RSM) central composite design (CCD) is used to optimize the operational parameters’ agitation time, adsorbent dosage, solution pH, and initial concentration of CR solution during the adsorption process. The agitation period of 29.48 min, the Cu/ZnONP dosage of 0.301 g/L, the solution pH of 6.96, and the CR initial concentration of 90 mg/L resulted in a maximum CR adsorption of 94.14% and a desirability of 0.976. The kinetic findings fit the pseudo-second-order kinetic equation, and the equilibrium data agreed with the Langmuir isotherm (maximum uptake capacity qmax = 250 mg/g). During the thermodynamic experiments, endothermic, spontaneous, and physical adsorptions were observed.
Schwinger-Type Pair Production in Non-SUSY AdS/CFT
Authors: Chowdhury Udit Narayan
Published: April 2023

We study pair production of particles in the presence of an external electric field in a large

N

non-supersymmetric Yang-Mills theory using the holographic duality. The dual geometry we consider is asymptotically AdS and is effectively parametrized by two parameters,

u

0

and

−

5
/
2

<
δ
≤
0

, both of which can be related to the effective mass of quark/antiquark for non-supersymmetric theories. We numerically calculate the interquark potential profile and the effective potential to study pair production and analytically find out the threshold electric field beyond which one gets catastrophic pair creation by studying rectangular Wilson loops using the holographic method. We also find out the critical electric field from DBI analysis of a probe brane. Our initial investigations reveal that the critical electric field necessary for spontaneous pair production increases or decreases w.r.t. its non-supersymmetric value depending on the parameter

δ

. Ultimately, we find out the pair production rate of particles in the presence of an external electric field by evaluating circular Wilson loops using perturbative methods. From the later investigation, we note the resemblance with our earlier prediction. However, we also see that for and below another certain value of the parameter

δ

, the pair production rate of particle/antiparticle pairs blows up as the external electric field is taken to zero. We thus infer that the vacuum of the non-SUSY gauge theory is unstable for a range of non-supersymmetric parameter

δ

and that the geometry/non-SUSY field theory under consideration has quite different characteristics than earlier reported.
Reversible Data Hiding in Encrypted Image via Joint Encoding of Multiple MSB and Pixel Difference
Authors: Kong Ping , Fu Di , Huang Lin , Zhou Liang , Li Jian , Qin Chuan
Published: April 2023

Reversible data hiding in encrypted image (RDHEI) has become a research hotspot, which can effectively protect image content privacy. An RDHEI scheme based on the joint encoding of multiple MSBs (most significant bits) and pixel difference is proposed in this paper. A block-based image encryption method is adopted on the content owner side, which can securely protect the image contents while retaining the spatial correlation within each block. By the joint encoding strategy of multiple MSB and pixel difference, the redundancy within the bit plane is sufficiently compressed to accommodate more additional data; thus, a high embedding rate can be achieved. According to different kinds of available keys, image decryption and data extraction can be separably conducted on the receiver side. Experimental results show that our scheme can achieve a higher embedding rate than some state-of-the-art schemes.
EVOCE Robot: Developing Prototypes and Teaching Young Learners English Vocabulary
Authors: Yuliani Sri , Linarta Arie , Rahmalisa Uci , Shalawati
Published: April 2023

This study aimed to find out the prototype of an EVOCE robot that gave impact of students’ English vocabularies enhancement. In this study, the authors used two types of research design, namely, prototyping method and experiment research design. The mixed method is applied in this research qualitatively and quantitatively. Both vocabulary tests and observational methods of prototyping data collection were employed. The robot prototype used in the class as a tool to examine how was the effect of this media helped young learners in acquiring basic English vocabulary. The prototype has been through the test and the result showed that it suited with the needs for young learners. Nonprobability sampling was the technique used. A total of 40 students from two classes made up the research sample. The vocabulary score achievement pre and post test using EVOCE robot was compared with data analysis and t-test. The findings of value of t-stat > t-table at the significant level of 5% (1,679 > 1,328) meaning that the robot helped students become better acquisition in getting new vocabulary and influenced their level of vocabulary score. As the result, this research therefore has consequences for the teacher’s understanding that the usage of robots can both increase students’ vocabulary and also have an impact on their level of English proficiency.
Multiview Feature Fusion Attention Convolutional Recurrent Neural Networks for EEG‐Based Emotion Recognition
Authors: Xin Ruihao , Miao Fengbo , Cong Ping , Zhang Fan , Xin Yongxian , Feng Xin
Published: April 2023

Emotion recognition is essential for computers to understand human emotions. Traditional EEG emotion recognition methods have significant limitations. To improve the accuracy of EEG emotion recognition, we propose a multiview feature fusion attention convolutional recurrent neural network (multi‐aCRNN) model. Multi‐aCRNN combines CNN, GRU, and attention mechanisms to fuse features from multiple perspectives deeply. Specifically, multiscale CNN can unite elements in the frequency and spatial domains through the convolution of different scales. The role of the attention mechanism is to weigh the frequency domain and spatial domain information of different periods to find more valuable temporal perspectives. Finally, the implicit feature representation is learned from the time domain through the bidirectional GRU to achieve the profound fusion of features from multiple perspectives in the time domain, frequency domain, and spatial domain. At the same time, for the noise problem, we use label smoothing to reduce the influence of label noise to achieve a better emotion recognition classification effect. Finally, the model is validated on the EEG data of 32 subjects on a public dataset (DEAP) by fivefold cross‐validation. Multi‐aCRNN achieves an average classification accuracy of 96.43% and 96.30% in arousal and valence classification tasks, respectively. In conclusion, multi‐aCRNN can better integrate EEG features from different angles and provide better classification results for emotion recognition.
A Lightweight, Secure Big Data‐Based Authentication and Key‐Agreement Scheme for IoT with Revocability
Authors: Zahednejad Behnam , Teng Huang , Kosari Saeed , Xiaojun Ren
Published: April 2023

With the rapid development of Internet of Things (IoT), designing a secure two‐factor authentication scheme for IoT is becoming increasingly demanding. Two‐factor protocols are deployed to achieve a higher security level than single‐factor protocols. Given the resource constraints of IoT devices, other factors such as biometrics are ruled out as additional authentication factors due to their large overhead. Smart cards are also prone to side‐channel attacks. Therefore, historical big data have gained interest recently as a novel authentication factor in IoT. In this paper, we show that existing big data‐based schemes fail to achieve their claimed security properties such as perfect forward secrecy (PFS), key compromise impersonation (KCI) resilience, and server compromise impersonation (SCI) resilience. Assuming a real strong attacker rather than a weak one, we show that previous schemes not only fail to provide KCI and SCI but also do not provide real two‐factor security and revocability and suffer inside attack. Then, we propose our novel scheme which can indeed provide real two‐factor security, PFS, KCI, and inside attack resilience and revocability of the client. Furthermore, our performance analysis shows that our scheme has reduced modular exponentiation operation and multiplication for both the client and the server compared to Liu et al.’s scheme which reduces the execution time by one third for security levels of λ = 128. Moreover, in order to cope with the potential threat of quantum computers, we suggest using lightweight XMSS signature schemes which provide the desired security properties with λ = 128 bit postquantum security. Finally, we prove the security of our proposed scheme formally using both the real‐or‐random model and the ProVerif analysis tool.
Substance P-Mediated Vascular Protection Ameliorates Bone Loss
Authors: Kim Doyoung , Piao Jiyuan , Park Jeong Seop , Lee Dahyun , Hwang Dae Yeon , Hong Hyun Sook
Published: April 2023

Estrogen deficiency causes bone loss via diverse pathological cellular events. The involvement of the vasculature in bone formation has been widely studied, and type H vasculature has been found to be closely related to bone healing. Ovariectomy- (OVX-) induced estrogen deficiency reduces type H vessel density and promotes reduction of bone density. Analysis of early events after OVX showed that estrogen deficiency preferentially induces oxidative stress, which might provoke endothelial dysfunction and reduce angiogenic factors systemically and locally. The instability of the vascular potential is expected to promote bone loss under estrogen deficiency. Substance P (SP) is an endogenous neuropeptide that controls inflammation and prevents cell death under pathological conditions. SP can elevate nitric oxide production in endothelial cells and inhibit endothelial dysfunction. This study is aimed at investigating the preventive effects of systemically injected SP on OVX-induced vascular loss and osteoporosis onset. SP was systemically administered to OVX rats twice a week for 4 weeks, immediately after OVX induction. OVX conditions could decrease antioxidant enzyme activity, type H vessels, and angiogenic growth factors in the bone marrow, followed by inflammation and bone loss. However, pretreatment with SP could block type H vessel loss, accompanied by the enrichment of nitric oxide and sustained angiogenic factors. SP-mediated early vascular protection inhibits bone density reduction. Altogether, this study suggests that early administration of SP can block osteoporosis development by modulating oxidative stress and protecting the bone vasculature and angiogenic paracrine potential at the initial stage of estrogen deficiency.
The Influence of Workload and Work Motivation on the Performance of Teachers
Authors: SOLANIA NIÑA , COÑADO EDWIN , PAGUTA MARK JOSEPH , VENTURA RAZELIZA , ARNADO ALVIC
Published: April 2023

Given the nature of the teacher’s job, it is expected that they have many workloads, both teaching-related and other functions. Literature suggests that too much workload for teachers may affect their teaching performance. In addition, work motivation is another factor affecting teachers’ performance, with studies suggesting that those who have high motivation also have the driving mechanism to accomplish tasks. Considering the challenging tasks teachers face on daily basis, this study aims to examine how workload and motivation influence teacher performance. Using descriptive-correlational research, a survey was conducted to 45 teachers of Butuan Central Elementary School to determine the influence of their workload and level of motivation on their performance. Results showed that 62% of the participants have an ideal workload of 2,400 minutes per week and only 29% are overloaded. In terms of motivation, results showed that the participants’ level of motivation is highly observed (M=4.15). This study also looked into the relationship among work performance, length of service, education, and age. It was found that only length of service has a significant correlation with performance, although both are negatively correlated (r= -0.359, p=.015). Moreover, the relationship among performance, workload and motivation was also examined. It was found that there is no significant relationship between performance and workload (r= -0.014, p=0.928) and performance and motivation (r=0.009, p=0.954). Overall, results of this study suggest that the length of service has a significant negative relationship with performance, while teachers’ workload and work motivation have no influence on their teaching performance.
Marketing in Regional Apparatus: A Regional Innovation Initiative to Build Institutional Identity, Image and Reputation
Authors: Aries Aries
Published: April 2023

Marketing is an ideal conception that has not been much in demand and has not been seen in its application in local governance and public services in Banten Province Regional Apparatus. The main cause of this is that there are no regulations and limited education about the importance of implementing marketing in regional apparatus. So that the application of marketing in regional devices needs to be used as a regional innovation initiative as stipulated in Government Regulation No. 38 of 2017 concerning Regional Innovation. Because with marketing, regional apparatus get tangible benefits; improve performance and as an effort to build identity, image and achieve institutional reputation.
Prospects and Problems of Tourism Industry in Sundarbans of Bangladesh
Authors: Aftab Mahadi Rimon Aftab Mahadi Rimon , Rina Rina Aktar , Nabila Akhi Nabila Akhi
Published: April 2023

Tourism is one of the ever-growing industries not only Bangladesh but also all around the world. Meanwhile, Sundarbans has considered as one of the best nature-based tourism sites in Bangladesh whilst few local peoples participate in this tourism sector. This study examines to analyze the present scenario of the tourism industry as well as identifying the different attractive tourist spots and its problems in the Sundarbans for analyzing the opportunities. Handling a self-administered interview schedule through convenience sampling, data were collected from 120 respondents who were obtained tourist spot in Sundarbans of Khulna Division. Findings showed that 88% tourist having knowledge about different tourist Spots of Sundarbans. The majority of the respondents (34%) visited to Koromjol and the other 29% in Herbaria, even 25% in Hiron Point. The different reasons of visiting a place, here, 46% tourist stayed this place along with 25% for place relaxation, even 17% for Study tour and 8% for research as well as 4% others purposes. The study clearly showed that satisfactory level of tourist of sundabans articulated by their ratings. 28% tourist are fully pleased, 35% tourist satisfactory level is good and 20% tourist are gratified. On the constant 13% tourist are dissatisfied and 4% tourist are very dissatisfied on the facilities on sundarbans. However, 33% tourist said developing infrastructure, 39% tourist ensuring tourist security, 17% tourist talking realistic policy as well as only 11% tourist suggested to other policy.
Village Financial Management In Teluk Kenidai Village, Tambang District, Kampar Regency In 2020
Authors: Salsabila Friscilla , Marta Auradian
Published: April 2023

The problem in this research is the planning and budgeting are not following the needs of the community, in terms of implementation they have not been able to realize the budget and do not prioritize important programs with existing finances, this is also caused by the lack of quality human resources in Teluk Kenidai Village. The purpose of this study is to find out and describe the process of financial governance and the factors that influence financial management in Teluk Kenidai Village, Tambang District, Kampar Regency in 2020. The approach in this research is to use a qualitative approach and the type of research is descriptive. The research location was carried out in Teluk Kenidai Village, Tambang District, Kampar Regency, using data collection techniques through interviews and documentation. The results showed that financial management in Teluk Kenidai Village, Tambang District, Kampar Regency was not optimal. Judging from the planning, it has not set a priority scale, so the people's needs are not met. In terms of implementation, it has not realized all that was planned. Then the reporting and accountability have not been carried out promptly, this is due to the lack of quality human resources.
SIMBLEFARON PADA PASIEN SJS PASCA VAKSINASI COVID-19: A NURSING CASE STUDY
Authors: Astari Dewanti Widya , Silviani Rikeu
Published: April 2023

Pendahuluan: Kasus simblefaron yang jarang terjadi pada pasien Stevens-Johnson Syndrome (SJS), dengan riwayat pasca vaksinasi Covid-19 satu tahun yang lalu.
Presentasi Kasus: Seorang wanita berusia 50 tahun, berasal dari Jawa Barat. Pasien menderita SJS satu tahun yang lalu dan kini mengalami simblefaron. Visus Oftalmicus Dextra Sinistra (ODS) Light Perception (LP) dengan palpebra ODS menyebutkan bahwa terdapat eritema, konjungtiva ODS, terdapat simblefaron, kornea sulit dinilai. Palpebra superior dan inferior menyatu. Pasien mengeluh perih dan sulit membuka mata.
Hasil: Asuhan keperawatan yang diberikan pada pasien dengan simblefaron diantaranya berfokus pada resiko jatuh dan mengatasi perburukan kerusakan integritas jaringan.
Kesimpulan: Intervensi keperawatan yang tepat dapat mengatasi perburukan kondisi kerusakan organ internal mata akibat simblefaron yang dapat mengakibatkan kebutaan. Pendidikan kesehatan merupakan bagian intervensi terpenting bagi pasien dalam upaya menghadapi kondisi penyakitnya.
REVIEW 5 TAHUN KARAKTERISTIK KLINIS PASIEN BENDA ASING INTRAOKULAR DI PMN RS MATA CICENDO
Authors: Desrina  , Virgana Rova , Kartasasmita Arief S. , Iskandar Erwin , Ihsan Grimaldi , Widyanatha Made Indra
Published: April 2023

Introduction: Intraocular foreign bodies (IOFBs) are defined as intraocularly retained, unintentional projectiles that require urgent diagnosis and treatment to prevent blindness or globe loss. IOFBs account for 18–41% of open globe injuries, and frequently cause severe visual loss in patients with ocular trauma.The purpose of this study are is to describe the characteristics of open-globe injuries with posterior segment intraocular foreign bodies (IOFB).
Subject and Methods: Retrospective data of all patients with posterior segment IOFBs from 2017 to 2022 was conducted. Data including demographics, mechanism of injury, type of IOFB, method of diagnosis, presenting examination, medical and surgical treatment, visual outcomes, and complications were recorded.
Result: There were 39 patients (eyes) with IOFB, 38 (97,4%) were male, 10 (25,6%) were 46-55 years old. The most common IOFB occurred at workplace 30 patient (85,7%), 29 (74,3%) were insuranced, surgery were performed 1- 4 days in 15 (38,5%. The most Ocular trauma score were 3 (38,5%) and 2 (35,9%) initial VA were light perception – hand movement (25 or 64,1%), final VA with BCVA were > 20/40 (30,8%) patients and 6/60-6/15 (25,6%). The posterior segment IOFB (51,3%, metallic IOFB 25 (61,5%). Cataract 74,3% and Endophthalmitis (20,5%) were found in initial examination patient with IOFB (13 or 37,1%). Late complication in post surgery IOFB patient was glaucoma 14,4%.
Conclusions: The IOFB occurred most commonly in adults, men, at the workplace. The IOFB mostly was metallic, found in the posterior segment. Cataract and endoftalmitis were common in initial finding IOFB patients.
Dois cancioneiros inacabados: os caminhos cruzados de Amadeu Amaral e Mário de Andrade
Authors: Cavalcanti Maria Laura Viveiros de Castro
Published: April 2023

Seguindo detalhes e dados marginais encontrados na bibliografia e nos acervos disponíveis, enfocamos a inter-relação de dois cancioneiros inacabados: “Cancioneiro caipira”, de Amadeu Amaral, e “Na pancada do ganzá”, de Mário de Andrade, concebidos respectivamente nos anos 1920 e 1930. Como ativos escritores sediados em São Paulo e interessados na criação artística e nas culturas populares tradicionais, seus caminhos se cruzaram nos ambientes em que se desenvolveu o modernismo. O artigo analisa esse relacionamento e lança luz sobre elos de continuidade nas visões modernistas das tradições populares e do folclore brasileiro.
Notas sobre a história da igreja Matriz de Santo Antônio, no distrito de Glaura, em Ouro Preto
Authors: Pedrosa Aziz José de Oliveira
Published: April 2023

A igreja Matriz de Santo Antônio, localizada no distrito de Glaura, em  Ouro Preto, foi reconstruída por volta de 1750 em substituição à antiga capela, erguida na década de 1720, que se encontrava em ruína. A história desse templo abrange notas importantes e necessárias para a compreensão do processo de produção da arte e da arquitetura setecentista em Minas Gerais. Este artigo objetiva relacionar informações sobre a história da referida igreja, obtidas a partir do exame de documentação primária, temática escassamente investigada na atualidade.
Grades e caixas
Authors: Pacheco Ana Paula
Published: April 2023

A seção Criação tem por objetivo publicar textos e materiais inéditos de escritores e/ou artistas, fotógrafos, desenhistas, além de documentos inéditos encontrados no Arquivo do IEB/USP. “Grades e caixas”, de Ana Paula Pacheco, reúne dois contos sobre o feminino. Pacheco é escritora e professora de Teoria Literária e Literatura Comparada na Universidade de São Paulo. “Pedaços de sonho, seguidos de considerações tecidas pelo Urso siberiano” se beneficia de estudos de Freud (1972), e de narrativas de Schnitzler (1987; 2008) e de Nastassja Martin (2021). “Pandora, a barata” incorpora livremente estudos de Erwin e Dora Panofsky (2009).
Ensaio sobre o chapéu: reflexões de Gilda de Mello e Souza a partir de um acessório da moda
Authors: Valle Rafael do
Published: April 2023

No presente artigo, por meio de uma análise textual, exploraremos a recorrente presença do chapéu nos ensaios da filósofa brasileira Gilda de Mello e Souza. Em O espírito das roupas, a autora defende que a moda é muito mais do que um artigo supérfluo. Recompondo-se a cada momento, jogando com o imprevisto, dependendo do gesto, a moda é a mais humana das artes. Um simples acessório como o chapéu pode materializar a alma humana, de forma que possamos ser interpretados por aquilo que usamos em nossa cabeça. O olhar pericial de nossa autora, atento aos detalhes, e que conseguiu ver numa peça do vestuário uma constelação de significados, será aqui também analisado ao confrontarmos seus ensaios e entrevistas.
Circulating Ectonucleotidases Signal Impaired Myocardial Perfusion at Rest and Stress
Authors: Kroll Rachel G. , Powell Corey , Chen Jun , Snider Natasha T. , St. Hilaire Cynthia , Reddy Akshay , Kim Judy , Pinsky David J. , Murthy Venkatesh L. , Sutton Nadia R.
Published: April 2023

Background

Ectonucleotidases maintain vascular homeostasis by metabolizing extracellular nucleotides, modulating inflammation and thrombosis, and potentially, myocardial flow through adenosine generation. Evidence implicates dysfunction or deficiency of ectonucleotidases CD39 or CD73 in human disease; the utility of measuring levels of circulating ectonucleotidases as plasma biomarkers of coronary artery dysfunction or disease has not been previously reported.

Methods and Results

A total of 529 individuals undergoing clinically indicated positron emission tomography stress testing between 2015 and 2019 were enrolled in this single‐center retrospective analysis. Baseline demographics, clinical data, nuclear stress test, and coronary artery calcium score variables were collected, as well as a blood sample. CD39 and CD73 levels were assessed as binary (detectable, undetectable) or continuous variables using ELISAs. Plasma CD39 was detectable in 24% of White and 8% of Black study participants (
P
=0.02). Of the clinical history variables examined, ectonucleotidase levels were most strongly associated with underlying liver disease and not other traditional coronary artery disease risk factors. Intriguingly, detection of circulating ectonucleotidase was inversely associated with stress myocardial blood flow (2.3±0.8 mL/min per g versus 2.7 mL/min per g±1.1 for detectable versus undetectable CD39 levels,
P
<0.001) and global myocardial flow reserve (Pearson correlation between myocardial flow reserve and log(CD73) −0.19,
P
<0.001). A subanalysis showed these differences held true independent of liver disease.

Conclusions

Vasodilatory adenosine is the expected product of local ectonucleotidase activity, yet these data support an inverse relationship between plasma ectonucleotidases, stress myocardial blood flow (CD39), and myocardial flow reserve (CD73). These findings support the conclusion that plasma levels of ectonucleotidases, which may be shed from the endothelial surface, contribute to reduced stress myocardial blood flow and myocardial flow reserve.
Incremental Value of Exercise ECG to Myocardial Perfusion Single‐Photon Emission Computed Tomography for Prediction of Cardiac Events
Authors: Kraen Morten , Akil Shahnaz , Hedén Bo , Berg Jonathan , Ostenfeld Ellen , Carlsson Marcus , Arheden Håkan , Engblom Henrik
Published: April 2023

Background

Both myocardial perfusion single‐photon emission computed tomography (MPS) and exercise ECG (Ex‐ECG) carry prognostic information in patients with stable chest pain. However, it is not fully understood if combining the findings of MPS and Ex‐ECG improves risk prediction. Current guidelines no longer recommend Ex‐ECG for diagnostic evaluation of chronic coronary syndrome, but Ex‐ECG could still be of incremental prognostic importance.

Methods and Results

This study comprised 908 consecutive patients (age 63.3±9.4 years, 49% male) who performed MPS with Ex‐ECG. Subjects were followed for 5 years. The end point was a composite of cardiovascular death, acute myocardial infarction, unstable angina, and unplanned percutaneous coronary intervention. National registry data and medical charts were used for end point allocation. Combining the findings of MPS and Ex‐ECG resulted in concordant evidence of ischemia in 72 patients or absence of ischemia in 634 patients. Discordant results were found in 202 patients (MPS−/Ex‐ECG+, n=126 and MPS+/Ex‐ECG−, n=76). During follow‐up, 95 events occurred. Annualized event rates significantly increased across groups (MPS−/Ex‐ECG− =1.3%, MPS−/Ex‐ECG+ =3.0%, MPS+/Ex‐ECG− =5.1% and MPS+/Ex‐ECG+ =8.0%). In multivariable analyses MPS was the strongest predictor regardless of Ex‐ECG findings (MPS+/Ex‐ECG−, hazard ratio [HR], 3.0,
P
=0.001 or MPS+/Ex‐ECG+, HR,4.0,
P
<0.001). However, an abnormal Ex‐ECG almost doubled the risk in subjects with normal MPS (MPS−/Ex‐ECG+, HR, 1.9,
P
=0.04).

Conclusions

In patients with chronic coronary syndrome, combining the results from MPS and Ex‐ECG led to improved risk prediction. Even though MPS is the stronger predictor, there is an incremental value of adding data from Ex‐ECG to MPS, especially in patients with normal MPS.
Aortic Dissection During Pregnancy and Puerperium: Contemporary Incidence and Outcomes in the United States
Authors: Wang Yunda , Yin Kanhua , Datar Yesh , Mohnot Joy , Nodoushani Ariana Y. , Zhan Yong , Karlson Karl J. , Edwards Niloo M. , Reardon Michael J. , Dobrilovic Nikola
Published: April 2023

Background

Aortic dissection (AD) during pregnancy and puerperium is a rare catastrophe with devastating consequences for both parent and fetus. Population‐level incidence trends and outcomes remain relatively undetermined.

Methods and Results

We queried a US population‐based health care database, the National Inpatient Sample, and identified all patients with a pregnancy‐related AD hospitalization from 2002 to 2017. In total, 472 pregnancy‐related AD hospitalizations (mean age, 30.9±0.6 years) were identified from 68 514 000 pregnancy‐related hospitalizations (0.69 per 100 000 pregnancy‐related hospitalizations), with 107 (22.7%) being type A and 365 (77.3%) being type B. The incidence of AD appeared to increase over the 16‐year study period but was not statistically significant (
P
for trend >0.05). Marfan syndrome, primary hypertension, and preeclampsia/eclampsia were found in 21.9%, 14.4%, and 11.5%, respectively. On multivariable logistic regression analysis, Marfan syndrome was associated with the highest risk of developing AD during pregnancy and puerperium (adjusted odds ratio, 3469.36 [95% CI, 1767.84–6831.75];
P
<0.001). The in‐hospital mortalities of AD, type A AD, and type B AD were 7.3%, 4.3%, and 8.1%, respectively. Length of hospital stay for the AD, type A AD, and type B AD groups were 7.7±0.8, 10.4±1.9, and 6.9±0.9 days, respectively.

Conclusions

We quantified population‐level incidence and in‐hospital mortality in the United States and observed an increase in the incidence of pregnancy‐related AD. In contrast, its in‐hospital mortality appears lower than that of non–pregnancy‐related AD.
Repeat Mitral Transcatheter Edge‐to‐Edge Repair for Recurrent Significant Mitral Regurgitation
Authors: Shechter Alon , Lee Mirae , Kaewkes Danon , Koren Ofir , Skaf Sabah , Chakravarty Tarun , Koseki Keita , Patel Vivek , Makkar Raj R. , Siegel Robert J.
Published: April 2023

Background

There are limited data on repeat mitral transcatheter edge‐to‐edge repair for recurrent significant mitral regurgitation (MR).

Methods and Results

We conducted a single‐center, retrospective analysis of consecutive patients referred to a second mitral transcatheter edge‐to‐edge repair after a technically successful first procedure. Clinical, laboratory, and echocardiographic measures were assessed up to 1 year after the intervention. The composite of all‐cause death or heart failure (HF) hospitalizations constituted the primary outcome. A total of 52 patients (median age, 81 [interquartile range, 76–87] years, 29 [55.8%] men, 26 [50.0%] with functional MR) met the inclusion criteria. MR recurrences were mostly related to progression of the underlying cardiac pathology. All procedures were technically successful. At 1 year, most patients with available records (n=24; 96.0%) experienced improvement in MR severity or New York Heart Association functional class that was statistically significant but numerically modest. Fourteen (26.9%) patients died or were hospitalized due to HF. These were higher‐risk cases with predominantly functional MR who mostly underwent an urgent procedure and exhibited more severe HF indices before the intervention, as well as an attenuated 1‐month clinical and echocardiographic response. Overall, 1‐year course was comparable to that experienced by patients who underwent only a first transcatheter edge‐to‐edge repair at our institution (n=902). Tricuspid regurgitation of greater than moderate grade was the only baseline parameter to independently predict the primary outcome.

Conclusions

Repeat mitral transcatheter edge‐to‐edge repair is feasible, safe, and clinically effective, especially in non‐functional MR patients without concomitant significant tricuspid regurgitation.
An Army Like Goats: A Semantic and Zoological Reconsideration of 1 Kings 20:27
Authors: Schreiner David B. , Greenwood Kyle R.
Published: April 2023

This article examines the tendencies surrounding 1 Kgs 20:27 and ultimately proposes an alternative translation for and understanding of the phrase כִּשְׁנֵי חֲשִׂפֵי עִזִּים. We open with a survey of major English translations and commentary by salient interpreters to emphasize tendencies associated with the passage. We then examine the grammar and semantics of the passage in conjunction with ancient translations in order to highlight a disconnect between the translations and the Hebrew text. We then evaluate a proposal from Amitai Baruchi-Unna and argue that while he properly considers behavioral traits of the genus Capra to explain the imagery of 1 Kgs 20:27, his proposal is ultimately deficient. In response, we consider the phrase כִּשְׁנֵי חֲשִׂפֵי עִזִּים in conjunction with specific behaviors and physiological characteristics of certain species within the genus Capra. We propose that the description of the Israelite army may recall specific behaviors and characteristics of rutting male goats.
Two new species of Onycocaris (Decapoda, Palaemonidae) from the central Pacific
Authors: De Grave Sammy , Park Jin-Ho , Anker Arthur
Published: April 2023

Two new species of the genus Onycocaris are described, based on single specimens from Fiji and Moorea respectively. Onycocaris iti sp. nov. is closely related to the relatively widespread species, O. seychellensis Bruce, 1971; whilst O. brucei sp. nov. is a pseudo-cryptic species allied to O. quadratophthalma (Balss, 1921).