bluuebunny/crossref_metadata_2025 huggingface dataset:
A visually guided swim assay for mouse models of human retinal disease recapitulates the multi-luminance mobility test in humans
Authors: Hassan Salma , Hsu Ying , Mayer Sara K. , Thomas Jacintha , Kothapalli Aishwarya , Helms Megan , Baker Sheila A. , Laird Joseph G. , Bhattarai Sajag , Drack Arlene V.
Published: January 2024

PURPOSE:

The purpose of this study was to develop a visually guided swim assay (VGSA) for measuring vision in mouse retinal disease models comparable to the multi-luminance mobility test (MLMT) utilized in human clinical trials.

METHODS:

Three mouse retinal disease models were studied: Bardet–Biedl syndrome type 1 (Bbs1M390R/M390R
), n = 5; Bardet–Biedl syndrome type 10 (Bbs10−/−
), n = 11; and X linked retinoschisis (retinoschisin knockout; Rs1-KO), n = 5. Controls were normally-sighted mice, n = 10. Eyeless Pax6Sey-Dey
mice, n = 4, were used to determine the performance of animals without vision in VGSA.

RESULTS:

Eyeless Pax6Sey-Dey
mice had a VGSA time-to-platform (TTP) 7X longer than normally-sighted controls (P < 0.0001). Controls demonstrated no difference in their TTP in both lighting conditions; the same was true for Pax6Sey-Dey
. At 4–6 M, Rs1-KO and Bbs10−/−
had longer TTP in the dark than controls (P = 0.0156 and P = 1.23 × 10−8, respectively). At 9–11 M, both BBS models had longer TTP than controls in light and dark with times similar to Pax6Sey-Dey
(P < 0.0001), demonstrating progressive vision loss in BBS models, but not in controls nor in Rs1-KO. At 1 M, Bbs10−/−
ERG light-adapted (cone) amplitudes were nonrecordable, resulting in a floor effect. VGSA did not reach a floor until 9–11 M. ERG combined rod/cone b-wave amplitudes were nonrecordable in all three mutant groups at 9–11 M, but VGSA still showed differences in visual function. ERG values correlate non-linearly with VGSA, and VGSA measured the continual decline of vision.

CONCLUSION:

ERG is no longer a useful endpoint once the nonrecordable level is reached. VGSA differentiates between different levels of vision, different ages, and different disease models even after ERG is nonrecordable, similar to the MLMT in humans.
TRANS-VQA: Fully Transformer-Based Image Question-Answering Model Using Question-guided Vision Attention
Authors: Koshti Dipali , Gupta Ashutosh , Kalla Mukesh , Sharma Arvind
Published: January 2024

Understanding multiple modalities and relating them is an easy task for humans. But for machines, this is a stimulating task. One such multi-modal reasoning task is Visual question answering which demands the machine to produce an answer for the natural language query asked based on the given image. Although plenty of work is done in this field, there is still a challenge of improving the answer prediction ability of the model and breaching human accuracy. A novel model for answering image-based questions based on a transformer has been proposed. The proposed model is a fully Transformer-based architecture that utilizes the power of a transformer for extracting language features as well as for performing joint understanding of question and image features. The proposed VQA model utilizes F-RCNN for image feature extraction. The retrieved language features and object-level image features are fed to a decoder inspired by the Bi-Directional Encoder Representation Transformer - BERT architecture that learns jointly the image characteristics directed by the question characteristics and rich representations of the image features are obtained. Extensive experimentation has been carried out to observe the effect of various hyperparameters on the performance of the model. The experimental results demonstrate that the model’s ability to predict the answer increases with the increase in the number of layers in the transformer’s encoder and decoder. The proposed model improves upon the previous models and is highly scalable due to the introduction of the BERT. Our best model reports 72.31% accuracy on the test-standard split of the VQAv2 dataset.
On the weighted Bojanov-Chebyshev problem and the sum of translates method of Fenton
Authors: Farkas Balint , Nagy Bela , Révész Szilárd György
Published: January 2024

Minimax and maximin problems are investigated for a special class of functions on the interval $[0,1]$. These functions are sums of translates of positive multiples of one kernel function and a very general external field function. Due to our very general setting the minimax, equioscillation and characterization results obtained extend those of Bojanov, Fenton, Hardin, Kendall, Saff, Ambrus, Ball and Erdélyi. Moreover, we discover a surprising intertwining phenomenon of interval maxima, which provides new information even in the most classical extremal problem of Chebyshev.
Bibliography: 25 titles.
Symmetric matrices and maximal Nijenhuis pencils
Authors: Konyaev Andrei Yur'evich
Published: January 2024

A Nijenhuis pencil is a linear subspace of the space of $(1,1)$ tensor field which consists of Nijenhuis operators. The problem of the description of maximal (by inclusion) Nijenhuis pencils containing a subpencil of dimension $n(n+1)/2$ such that the operators in it are - in some system of coordinates - constant symmetric matrices, is solved. Two such pencils turn out to exist, both of which arise in a natural way in applications, for example, in the theory of infinite-dimensional integrable systems.
Bibliography: 6 titles.
A critique on English homophones and homographs
Authors: Simon Chipanda
Published: January 2024

This paper critiques the treatment of English homographs and homophones in linguistic literatures. The study is motivated by the fact that the available data are questionable on the subject, thus calling for re-analysis. Methodologically, the study is a critical analysis of data obtained through a documentary process in secondary reading. The study employs the Semantic Theory and the Referential Theory of Meaning as the basis of data analysis. These theories explain lexemes in terms of how they are articulated and what they refer to. The findings of the analysis reveal that most of the linguistic literatures offer contestable and confusing definitions of homographs/homophones. For instance ‘affect’ and ‘effect’, just like’ profit’ and ‘prophet’, are not homophones though they are regarded as so in some available literature. Also, ‘conduct’ (N) and ‘conduct’ (V) are regarded as homographs but in reality they are not. Therefore, homophones are words with the same pronunciation but different spellings and meanings while homographs are words that are spelt the same but pronounced differently and have different meanings as the case of 'live' (verb) /lɪv/ and ‘live’ (adjective) /laɪv/.
Acknowledgements (2021-2022)
Authors: -Editors in Chiefs Cameroon J Exp Biol
Published: January 2024

Reviewers of the period from January 2021 to December 2022
Micropropagation from cotyledonary explants of grapefruit (Citrus paradisi Macf.) by indirect and direct organogenesis
Authors: Tchoutang Nzepang Darius , Tonfack Libert Brice , Mir Bilal Ahmad , Noumsi Foamouhoue Emmanuel , Youmbi Emmanuel
Published: January 2024

Grapefruit (Citrus paradisi Macf.) is an economic fruit crop worldwide cultivated for its nutritional value, and aromatic flavours. However, the development of new varieties and high production of quality seedling constitutes a limit to improving grapefruit yields. An efficient regeneration protocol could be of great interest for grapefruit transformation, micropropagation, and germplasm conservation. In vitro plant regeneration systems of Citrus paradisi have been studied by using cotyledonary explants. Different concentrations of plant growth regulators were used to explore the organogenic potential of cotyledonary explants under laboratory conditions. For indirect organogenesis using cotyledon segment explants, a low concentration of 2,4-dichlorophenoxyacetic acid (2,4-D) lead to the formation of white callus, while a high concentration of 2,4-D induced brown callus and adventitious root differentiation. The best response for callogenesis was obtained on Murashige and Skoog (MS) medium supplemented with 2 mg/L of 2,4-D. Only brown callus cultured on MS added with 2 mg/L 6-benzylaminopurine (BAP) has regenerated shoots, but the percentage of callus producing shoots was very low (6.66 ± 2.68%). Regarding direct organogenesis from the cotyledonary node explants, the best response for shoot proliferation was observed on MS supplemented with 4 mg/L BAP (86.66 ± 12.58% of explants regenerating shoots, and an average number of 5.45 ± 0.45 shoots per explant). Low percentages of In vitro rooting of regenerated shoots were observed with different concentrations of α-naphthalene acetic acid (NAA) or indole-3-butyric acid (IBA). Nevertheless, the highest rooting percentage (13.33 ± 2.88%) was obtained on MS containing 2 mg/L NAA. These results provide new information for mass regeneration and the production of healthy seedlings, and can be applied in grapefruit improvement programs.
Potential effect of MSR1 and C6 ceramide small molecules on nasopharyngeal carcinoma based on GSEA analysis
Authors: Wen Haitao , Yang Guangrun , Guo Zhong , Fan Lixia , Chen Bowen , Zhang Dapeng , Zhou Jiafu
Published: January 2024

Purpose: To investigate some potential therapeutic agents and targets for nasopharyngeal carcinoma (NPC).

Methods: Some potential therapeutic agents and target genes for NPC were identified by integrating bioinformatic analysis and in vitro experimental validation. Three datasets of NPC patients were gathered to reveal 26 upregulated and 344 downregulated differentially expressed genes (DGEs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway analysis (KEGG) of the DGEs were implemented. Separately, 316 drug and small molecule target genes were acquired from the SEA database, allowing for detection of C6-ceramide as a small molecule of high relevance to NPC. Then, the differentially upregulated genes were intersected with potential target genes of C6-ceramide small molecules to obtain macrophage scavenger receptor 1 (MSR1). Finally, the study validated the potential roles of MSR1 and C6-ceramide in NPC cell lines.

Results: Knockdown of MSR1 expressions in NPC cells significantly decreased cell viability. Treatment with 10 μmol/L C6-ceramide also significantly reduced NPC cell viability (p < 0.0001). Furthermore, C6-ceramide attenuated the increase in MSR1 levels induced by MSR1 overexpression in NPC cells (p < 0.0001). Concurrently, MSR1 knockdown decreased expression of PI3K and AKT, while MSR1 overexpression upregulated AKT and PI3K levels.

Conclusion: MSR1 modulates viability of NPC cells by regulating PI3K and AKT expression. Additionally, C6-ceramide exerts therapeutic effect on NPC by regulating MSR1 expression. These findings reveal new therapeutic targets and strategies for the clinical management of NPC. These results establish a rationale for further exploration of MSR1 and ceramides as novel targets in NPC.
Innovative Techniques in Egyptian Vulture Conservation
Authors: Authors
Published: January 2024

Abstracts in fulltext.
Egyptian Vulture status in Europe
Authors: Authors
Published: January 2024

No Abstract
DİYALİZ HASTALARININ AİLE İŞLEVSELLİĞİ ÜZERİNE NİCEL BİR ARAŞTIRMA
Authors: YAVUZ Elvan , ÇALIK VAR Esra
Published: January 2024

Bu araştırmanın amacı kronik böbrek yetmezliğine sahip olup, diyalize girmek zorunda olan, hastalığından dolayı zamanının belli bir kısmını diyalizde geçiren diyaliz hastalarının aile işlevselliklerinin bazı değişkenlere göre incelenmesidir. Araştırmanın çalışma grubunu Ankara’da bulunan iki özel diyaliz merkezi ve bir üniversite hastanesinin diyaliz bölümünde tedavi olan 200 hasta oluşturmaktadır. Araştırmada kişisel bilgi formu ve aile değerlendirme ölçeği (ADÖ) veri toplama aracı olarak kullanılmıştır. Araştırma verilerine göre, katılımcıların çoğu erkektir, 46-60 yaş aralığındadır, lise mezunudur, 1-5 yıldır kronik böbrek yetmezliğine sahiptir, hastalığından dolayı herhangi bir sosyal hizmet kurumundan yararlanmayanların oranı fazladır. Araştırmanın sonucuna göre, hastaların; medeni durum, çocuk sayısı, ekonomik durumu, çalışma durumları, eğitim durumu, aile üyelerinde kronik hastalık bulunma durumu ile ilgili değişkenler aile işlevselliğini farklılaştırmaktadır.
KADINLARDA KAYGI DÜZEYİ VE BENLİK SAYGISI ARASINDAKİ İLİŞKİNİN DEĞERLENDİRİLMESİ VE KADINLARIN SOSYAL HİZMET İHTİYAÇLARININ BELİRLENMESİ
Authors: TAHTACI Ali , ÖZMETE Emine
Published: January 2024

Bu çalışma Sağlıklı Hayat Merkezi Psikososyal Danışmanlık Birimleri’ne başvuran kadınlarda kaygı düzeyi ve benlik saygısı arasındaki ilişkinin değerlendirilmesi ve kadınların sosyal hizmet ihtiyaçlarının belirlenmesi amacıyla yapılmıştır. Bu araştırmada nicel araştırma yöntemlerinden olan “ilişkisel tarama modeli” kullanılmıştır. Araştırmanın örneklemini Sağlıklı Hayat Merkezi Psikososyal Danışmanlık Birimleri’ne başvuran 18-65 yaş aralığındaki araştırmaya gönüllü katılan kadın başvuranlar oluşturmaktadır. Araştırmada kadın başvuranların kaygı ölçeğinden aldıkları ortalama puan değerinin 20.82±12.97; benlik saygısı envanterinden aldıkları ortalama puan değerinin 54.49±22.54 olduğu belirlenmiştir. Araştırmada kadınlarda kaygı düzeyi arttıkça benlik saygısının azaldığı belirlenmiştir (r=-0.419, p
YAŞLILARDA TEKNOLOJİ KULLANIMININ TOPLUMSAL HAYATA KATILIMA VE BAŞARILI YAŞLANMAYA ETKİSİNİN İNCELENMESİ
Authors: HANÇEROĞLU KANDEMİR Buse , PAK GÜRE Merve Deniz
Published: January 2024

Araştırmanın amacı yaşlıların teknoloji kullanımının toplumsal hayata katılıma ve başarılı yaşlanmaya etkisinin incelenmesidir. Araştırma ilişkisel tarama modelinde gerçekleştirilmiştir. Yaşlı refahı alanındaki sivil toplum kuruluşlarına üye 65 yaş üstü 191 katılımcı araştırmaya katılmıştır. Veri toplamak amacıyla sosyodemografik soru formu, Başarılı Yaşlanma Ölçeği, Toplumsal Yaşama Katılım Envanteri ve Teknoloji Kullanım Ölçeği kullanılmıştır. Veriler SPSS 22.0 programıyla analiz edilmiştir. Katılımcıların %55,5’i kadındır ve ortalama yaş 69.56±6.118’dir. %95.29’unun teknolojik cihazı, %90.1’inin internete erişimi ve %57.6’sının sosyal medya hesabı vardır. Toplumsal Yaşama Katılım Envanteri puan ortalaması 4.32±3.26’dır ve ortalama altında skorlar elde edilmiştir. Başarılı Yaşlanma Ölçeği puan ortalaması 53.42±11.10’dur, skorlar ortalamanın üzerindedir. Teknoloji Kullanım Ölçeği puan ortalaması 37.24±9.08’dir ve ortalama üstünde skorlar elde edilmiştir. Teknoloji Kullanım Ölçeği puanları ile Başarılı Yaşlanma Ölçeği puanları arasında pozitif yönlü korelasyon bulunmaktadır. Sonuç olarak, yaşlıların teknolojik gelişmelere uyum sağlaması amacıyla başarılı yaşlanma ve toplumsal hayata katılımın artması için sosyal hizmet uzmanlarının danışman, eğitici ve kaynak geliştirici roller üstlenmesi önerilebilir.
TEKNOLOJİ ÇAĞININ KONUŞULMAYAN GÜNDEMİ: ÇEVRİM İÇİ ÇOCUK CİNSEL İSTİSMARI
Authors: BARUT-BEKTAŞ Berçem
Published: January 2024

İnternetin dünya tarihine girmesiyle hız kazanan teknolojik ilerlemelerin etki ettiği alanların sayısı günden güne artmaktadır. Bu etkiler çok yönlü olmakla birlikte bazı olguların evirilmesine de aracılık etmektedir. Bilgi ve iletişim teknolojilerinin yaygınlaşması, internet kullanımının artması her yaşta bireylere yeni kullanım alışkanlıkları edindirmiştir. İnternet kullanımının yaygınlaşması ile beraber çocukların da dijital platformlarda geçirdiği zamanın arttığı bilinmektedir. Bu zaman çocuklar için eğlence, öğrenme, zaman geçirme gibi nitelikler barındırsa da aynı zamanda sanal platformlarda çeşitli biçimlerde cinsel istismara maruz kalma potansiyeli taşımaktadır. Çevrim içi çocuk cinsel istismarının yaygınlığının dikkat çekmesi ve konuya ilişkin literatürün giderek artmasıyla birlikte, bu konudaki temel tanımlayıcı ve açıklayıcı kavramlara ve bilgilere ihtiyaç artmaktadır. Bu çalışma literatür taraması yoluyla, çevrim içi çocuk cinsel istismarı kavramı ve kapsamı hakkında bilgi vermeyi amaçlamaktadır. Çalışma aynı zamanda sosyal hizmet perspektifinden konunun çocuk ve aile refahı için önemine dikkat çekerek uygulayıcılar ve yeni araştırmacılar için birtakım önerilerde bulunmayı hedeflemektedir.
On the protected nodes in exponential recursive trees
Authors: Javanian Mehri , Aguech Rafik
Published: January 2024

The exponential recursive trees model several kinds of networks. At each step of growing of these trees, each node independently attracts a new node with probability p, or fails to do with probability 1 − p. Here, we investigate the number of protected nodes, total path length of protected nodes, and a mean study of the protected node profile of such trees.
Depth lower bounds in Stabbing Planes for combinatorial principles
Authors: Dantchev Stefan , Galesi Nicola , Ghani Abdul , Martin Barnaby
Published: January 2024

Stabbing Planes (also known as Branch and Cut) is a proof system introduced
very recently which, informally speaking, extends the DPLL method by branching
on integer linear inequalities instead of single variables. The techniques
known so far to prove size and depth lower bounds for Stabbing Planes are
generalizations of those used for the Cutting Planes proof system. For size
lower bounds these are established by monotone circuit arguments, while for
depth these are found via communication complexity and protection. As such
these bounds apply for lifted versions of combinatorial statements. Rank lower
bounds for Cutting Planes are also obtained by geometric arguments called
protection lemmas.
In this work we introduce two new geometric approaches to prove size/depth
lower bounds in Stabbing Planes working for any formula: (1) the antichain
method, relying on Sperner's Theorem and (2) the covering method which uses
results on essential coverings of the boolean cube by linear polynomials, which
in turn relies on Alon's combinatorial Nullenstellensatz.
We demonstrate their use on classes of combinatorial principles such as the
Pigeonhole principle, the Tseitin contradictions and the Linear Ordering
Principle. By the first method we prove almost linear size lower bounds and
optimal logarithmic depth lower bounds for the Pigeonhole principle and
analogous lower bounds for the Tseitin contradictions over the complete graph
and for the Linear Ordering Principle. By the covering method we obtain a
superlinear size lower bound and a logarithmic depth lower bound for Stabbing
Planes proof of Tseitin contradictions over a grid graph.
A Bit of Nondeterminism Makes Pushdown Automata Expressive and Succinct
Authors: Guha Shibashis , Jecker Ismaël , Lehtinen Karoliina , Zimmermann Martin
Published: January 2024

We study the expressiveness and succinctness of history-deterministic
pushdown automata (HD-PDA) over finite words, that is, pushdown automata whose
nondeterminism can be resolved based on the run constructed so far, but
independently of the remainder of the input word. These are also known as
good-for-games pushdown automata. We prove that HD-PDA recognise more languages
than deterministic PDA (DPDA) but not all context-free languages (CFL). This
class is orthogonal to unambiguous CFL. We further show that HD-PDA can be
exponentially more succinct than DPDA, while PDA can be double-exponentially
more succinct than HD-PDA. We also study HDness in visibly pushdown automata
(VPA), which enjoy better closure properties than PDA, and for which we show
that deciding HDness is ExpTime-complete. HD-VPA can be exponentially more
succinct than deterministic VPA, while VPA can be exponentially more succinct
than HD-VPA. Both of these lower bounds are tight. We then compare HD-PDA with
PDA for which composition with games is well-behaved, i.e. good-for-games
automata. We show that these two notions coincide, but only if we consider
potentially infinitely branching games. Finally, we study the complexity of
resolving nondeterminism in HD-PDA. Every HDPDA has a positional resolver, a
function that resolves nondeterminism and that is only dependant on the current
configuration. Pushdown transducers are sufficient to implement the resolvers
of HD-VPA, but not those of HD-PDA. HD-PDA with finite-state resolvers are
determinisable.
Sustainable future and the general education
Authors: Yun Wooseob
Published: January 2024

Education is an activity of helping people to live independently. The essential aspect of education lies in the fact that the man of today teaches the man of tomorrow. Although tomorrow will be made by the choices what we make today, the responsibility for tomorrow is not on our shoulders but on the shoulders of next generation. The fundamental dilemma of education reveals itself in the reality of that we who cannot take over the responsibility for the future have to educate the next generation who cannot avoid that responsibility for their own times, especially in the period of rapid changes occurring nowadays. We have to educate the next generation to be able to get over the crisis and threats of the future bravely facing to the changes and overcoming the challenges. The crisis are very: the crisis of peace and democracy and the one of rapid climate change; on the one hand, on the other hand the threats comes from the unstable job markets. Education has to provide endless abilities with which the next generation will surmount the crisis and adjust themselves with the changes. The abilities are of critical thinking, humility, moral judgment, caring, inclusion, communication, and of self-learning that the next generation has to cultivate throughout their life. Only then will future sustainability be secured. The cultivation of these qualities is also the goal of both human formation education and civic education. General education at universities also aims the cultivation of these qualities. The times, therefore, demand that universities provide more elaborated general education. Global crises and changes affect dramatically East Asia. East Asia has unfortunate histories, sometimes summoned by politics. The ill-fated histories amplify these crises and cause regional tensions. In order to build a healthy foundation for life in East Asia, it is a urgent necessity to carry out collaborative research among general educators and the development of joint educational programs for the students in the region.
Reconsidering the Meaning of ‘Visual Literacy’ in the Age of AI : Applications to Liberal Arts Education and Possible Extensions
Authors: Jeong Ok-Hee
Published: January 2024

Literacy is an important driving force when it comes to attaining a critical eye for the real world, as well as for analyzing problems in the past and making predictions for the future. Since literacy is evolving in a new paradigm for human lifestyles and abilities, in no small part thanks to the rapid development of AI(Artificial Intelligence) and robot technology, this study begins with a review of the change in the meaning of literacy. Next, we consider the meaning of ‘visual literacy’, in an era when AI reads and analyzes information such as images and texts, as well as visual recognition, voice recognition, and decision-making through algorithms, and creates art in a new way. The ultimate purpose of this study is to argue for the need to change the meaning of ‘visual literacy’ as a driving force for visual communication based on imagination in terms of technological utilization, critical thinking, and ethical social problem solving. Therefore, the content of this study emphasizes both a utopian and dystopian aesthetic vision, as well as critical thinking, in terms of potential and expandability of AI, rethinking the meaning of ‘visual literacy’ at the ethical level with human autonomous judgment and a sense of responsibility. The results of this study demonstrate the need for us to apply ‘visual literacy’ in a way that combines imagination and critical thinking, as well as our need to develop a new way of visual cognition necessary for the acquisition and use of digital technology in terms of the role of liberal arts education in universities. Through this study, I argue that the application of ‘visual literacy’ to foster democratic citizenship qualities can help us expand new possibilities for the role of liberal arts education in the era of AI by giving us the authority to understand and utilize digital media based on imagination for image and text information processing technology and visual communication.
An Study on Curriculum Operation Strategies for the Introduction of University Career Developing Credit Systems
Authors: Park Sangwoo , Kang Jihye
Published: January 2024

This study was conducted to develop and institutionalize a university career education program called the ‘Career Developing Credit System.’ To achieve this, the research engaged in discussions with members of the academic community at University C, resulting in the derivation of an initial career education curriculum model. To validate the feasibility of this derived career education curriculum roadmap and its organization and operation strategies, two rounds of surveys were conducted with five educational experts. The findings are as follows: Firstly, this study established four core objectives, namely ‘career assessment,’ ‘career planning,’ ‘employment competency development,’ and ‘preparation for social integration.’ It presented a career education curriculum roadmap that combines general and major coursework, student-designed and executed career activities for credit recognition, and co-curricular programs to support these objectives. Secondly, the study provided concrete operational strategies for implementing and running the proposed career education curriculum roadmap. The results of this research aim to offer practical guidance to universities considering the Career Developing Credit System, as well as to provide foundational data and insights for career education research to promote the spread of university career education programs.
Educational Implications and Application of Compassion Meditation as Liberal Arts Education
Authors: Jeong Jaewon
Published: January 2024

The purpose of this study was to explore the educational implications of compassion meditation as a liberal arts education course and to see how it can be designed as within the regular curriculum. Recent studies have shown that compassion meditation promotes positive emotions and pro-social behavior. Furthermore, it has been actively used in education beyond the field of psychotherapy. The educational implications of compassion meditation in higher education are threefold. First, compassion meditation can create an inner shift that allows for existential reflection on the self. Second, compassion meditation is a metacognitive training exercise that enhances the ability for one to see the big picture. Third, compassion meditation is an approach that enhances pro-social behavior by improving empathy and compassion. In addition, I presented pedagogical suggestions on how compassion meditation can be designed as a liberal arts education course in universities. The significance of this study is that it analyzed the educational implications of compassion meditation, which fosters positive emotions toward oneself and enhances empathy toward others. The study also explored how compassion meditation can be designed as a liberal arts education course in the context of a serious psychological crisis among young adults.
The Nature and Criteria of Liberal Arts Education Courses
Authors: Paek Seungsu
Published: January 2024

This article explores the criteria of general education courses to clarify and solidify the identity of these courses. The study aims to derive the nature of general education courses by examining their formation and historical development, identifying distorting factors, and establishing criteria for them. General education courses have evolved from the liberal arts traditions of ancient Greece and Rome, forming a complex multilayered structure with four intertwining layers: liberal subjects, humanities subjects, general subjects, and core subjects. Originating from the comprehensive development of the liberal arts and shared experiences, general education courses, have possessed distinctive characteristics such as truth-seeking, personality development, universality, and core orientation since their inception.To preserve and enhance the essential nature of general education courses, it is crucial to eliminate distortions such as narrow specialization, superficial practicality, frivolous convenience, and overall irresponsibility. Overcoming persistent distortions and restoring the fundamental nature of general education courses requires establishing criteria. The starting point for this is acknowledging the premise that there are certain courses suitable for general education. General education courses demonstrate their suitability through educational, purposive, civilizational, academic, and objective criteria. These courses serve as dynamic complexes that internalize universal human values while shaping one's unique personality. In the era of digital transformation, the authenticity of education must strive to create genuinely characteristic general education courses.
Exploring the Utilization and Application of Mass Spectrophotometry across Various Fields within Clinical Laboratory Science
Authors: Kumari Ankita , Kambo Kanika , ul Islam Shahid
Published: January 2024

This review paper provides a thorough examination of the use of Mass Spectrophotometry in clinical laboratory science. Mass spectroscopy is a strong analytical tool that has transformed clinical diagnostics and research. This paper looks at how mass spectrometers are used in clinical laboratory science, drug testing and monitoring, newborn screening, toxicology clinical diagnostics, biomarker identification, and proteomics research. The report also examines the benefits and drawbacks of using a mass spectrophotometer in clinical laboratory settings. The findings demonstrate the importance of mass spectrophotometers in enhancing patient care, disease detection, and scientific understanding in the clinical laboratory sector.
Apresentação - Dossiê - Formas Autoritárias de ontem e hoje
Authors: Teixeira da Silva Francisco Carlos , Azevedo Cazetta Felipe
Published: January 2024

Apresentação - Dossiê - Formas Autoritárias de ontem e hoje
Pacto resolutorio expreso algunos comentarios sobre su regulación civil y registral
Authors: Ortega Piana Marco Antonio
Published: January 2024

Ante un grave incumplimiento de obligaciones, y habiendo perdido interés en la prestación debida, el acreedor, como parte fiel de la respectiva relación jurídica, puede optar por invocar el pacto que hubiese sido expresamente con venido, resolviendo por dicha razón el respectivo contrato por el solo mérito de la respectiva comunicación. Siendo la llamada cláusula resolutoria expresa una figura que no debería generar mayor discusión, esta última se presenta en lo relativo al contenido del pacto y a la forma de ejercer el respectivo derecho potestativo. Conviene, en consecuencia, considerar qué es lo que se propuso el legislador en el marco de la autonomía privada, dado que la libertad de configuración debe ejercerse en correspondencia con la racionalidad de la respectiva figura a aplicar y las normas imperativas, límite infranqueable. El tema adquiere singular relevancia porque la normativa registral permite que una resolución derivada del ejercicio del pacto resolutorio expreso sea inscrita a solicitud del interesado, del acreedor, de manera concreta de quien transfirió registralmente la propiedad de un inmueble, quien readquiría dicha propie dad, con eficacia que no se limita interpartes, sino erga omnes.
Agotamiento del derecho de marca, importaciones paralelas y comercio internacional
Authors: Benites Arrieta Gabriel
Published: January 2024

El principio del agotamiento del derecho es una de las materias más discu tidas en el derecho de la propiedad intelectual, y se ubica en medio de un debate que, hasta la fecha, no culmina con un acuerdo de alcance global. Sin embargo, su aplicación se encuentra presente en todos los países, y la evalua ción de sus efectos ha merecido la atención de la doctrina y de las cortes de justicia del mundo.
El presente trabajo se concentra en el campo de las marcas y trata de mos trar una perspectiva general sobre el agotamiento del derecho y su presencia en el comercio internacional a través de las importaciones paralelas. Asimis mo, incluye algunas de las razones económicas que fundamentan la existen cia o restricción de las importaciones paralelas, así como un análisis sobre su regulación en el derecho del comercio internacional
Las garantías preferidas en la regulación bancaria
Authors: Raygada Castillo Miguel Angel
Published: January 2024

Las garantías preferidas son una de las herramientas más importantes que tiene la regulación bancaria peruana para mitigar el riesgo crediticio y fortalecer la solidez de las instituciones del sistema financiero, reduciendo la probabilidad de quiebras y crisis financieras. Su función principal, además de respaldar los créditos, es motivar a dichas entidades a requerir a sus clientes la constitución de esta clase de garantías. Esto les permite expandir los límites legales individuales de financiamiento, al tiempo que reducen las provisiones necesarias, en caso de que los prestatarios vean disminuida su calificación crediticia. El presente artículo se sumerge en la lógica subyacente de la regulación de las garantías preferidas y explora en detalle este concepto en el ámbito financiero y legal.
Digitalna transformacija organizacije
Authors: Lozić Joško
Published: January 2024

Cilj je ovog rada utvrditi razliku među temeljnim pojmovima povezanim s procesom digitalne transformacije organizacije. Proces započinje digitizacijom pojedinih procesa i proizvodnih cjelina, a završava cjelokupnom digitalnom transformacijom organizacije. Proces je poznat pod nazivom digitalizacija, što ujedno podrazumijeva sve faze transformacije kroz koje organizacija prolazi. Proces digitalizacije usmjeren je k smanjenju troškova proizvodnje, odnosno povećanju prihoda, što čini temeljeni dio optimizacije proizvodnog procesa. U radu se posebno obrađuju sve faze procesa kako bi se naglasak stavio na kontinuitet digitalne transformacije. Jednom dostignuta razina digitalne transformacije temelj je za racionalizaciju proizvodnog procesa, optimizaciju troškova te daljnju digitalnu transformaciju na temelju usvajanja novih tehnoloških rješenja.
Analisis Performa Penetasan dan Sifat Tingkah Laku Mengeram pada Ayam Kampung
Authors: Yusuf Yusuf , Junaedi Junaedi , Suparman Suparman , Khaeruddin Khaeruddin
Published: January 2024

Penelitian ini bertujuan untuk mengetahui performa penetasan dan karakteristik tingkah laku mengeram pada ayam Kampung. Materi penelitian ini adalah ayam Kampung induk sebanyak 5 ekor, dan telur yang akan ditetasi sebanyak 11 butir per indukan. Parameter penelitian ini adalah berat badan induk, berat telur tetas, daya tunas, daya tetas, penyusutan telur, berat DOC, jumlah dan lama turun saat mengeram, suhu pengeraman dan reaksi ayam ketika didekati. Analisis data yang digunakan dalam penelitian ini adalah Analisis Deskriptif. Berdasarkan penelitian yang telah dilakukan maka diperoleh berat badan induk ayam yang mengeram 979.6-1350 g, berat telur tetas 41.9-47.4 g, daya tunas 81.63%, daya tetas 91.06%, penyusutan telur 11.97%, berat DOC 35.35 g, jumlah dan lama turun saat mengeram masing-masing 6.6 kali dan 42.06 menit, suhu pengeraman 37.97-38.19 °C dan reaksi ayam yang mengeram ketika didekati adalah selalu menyerang.
Analisis Strategi dan Metode Pembelajaran Bahasa Indonesia dengan Hasil Belajar Siswa di Sekolah Dasar Kelas 5
Authors: Ristiantita Monica , Sari Ainiyyah Yunita , Azahra Najwa Apriliani , Winarsih Indri Okta , Alkhoiri Muhammad Faiz , Mubarak M. Fadli , Mayarni Mayarni
Published: January 2024

Pembelajaran Bahasa Indonesia di jenjang SD diarahkan untuk memperoleh dimensi kompetensi pemahaman, keterampilan ilmiah, dan sikap ilmiah dalam berperilaku sehari-hari saat interaksi bersama masyarakat, lingkungan, juga pemanfaatan teknologi. Dari hasil wawancara yang dilakukan kepada guru di 6 sekolah, terdapat berbagai metode pembelajaran yang diterapkan oleh Guru kepada siswanya, yaitu metode PBL, PJBL, diskusi, ceramah, role playing . Guru-guru di 6 sekolah ini di pembelajaran Bahasa Indonesia melakukan strategi berbasis empati. Penggunaan strategi berbasis empati oleh guru dalam kegiatan belajar mengajar pada kelas 5 SD sangat positif dan dapat memberikan dampak yang signifikan pada proses pembelajaran. Ketika guru mengadopsi pendekatan ini, mereka menunjukkan kepedulian terhadap kebutuhan, perasaan, dan pengalaman siswa. Tanggapan positif pertama adalah terciptanya hubungan yang lebih baik antara guru dan siswa. Dengan memahami latar belakang dan perasaan siswa, guru dapat menciptakan lingkungan belajar yang inklusif dan ramah. Dimana hal tersebut merupakan suatu strategi pembelajaran yang  inovatif.
Development of Science Teaching Module Based on Environmentally for Student at MTsN Barru
Authors: Muchlisa Nurul , Arsyad Muhammad , Helmi Helmi
Published: January 2024

This research on the development of environment-based science teaching modules aims to: 1) to analyze the results of the validity of the content of science teaching module based on environment which meet valid criteria, 2) to analyze practitioners' assessments of environment-based science teaching modules, 3) to analyze the effectiveness of cience teaching module based on environment. The test subjects for this research were 23 class VIII students at MTsN Barru. The research method with 4D model. The instruments used in this research were validation sheets, practitioner assessment questionnaires, and test instruments for students' science learning outcomes. The practicality criteria are seen from practitioners' assessments of the teaching modules, and the effectiveness criteria are seen from the average percentage gain score increasing students' science learning outcomes. Based on the results of the analysis, the following conclusions were obtained: (1) the science teaching module based on environment developed based on expert assessment using Aiken's V index analysis was declared valid and suitable for use with minor revisions; (2) the science teaching module based on environment in terms of teacher responses is in the very good category; (3) the effectiveness of the science teaching module based on environment, which was analyzed using N-gain, obtained an average value of 0.56, which is in the medium category with a percentage of 56.46%, which means that there is an increase in students' science learning outcomes so it can be said that The science teaching module based on environment developed is effective and can improve students' science learning outcomes.
Década internacional da água 2018-2028: caminhos para o desenvolvimento
Authors: Hafemann Ana Claudia
Published: January 2024

Em todo o mundo, milhões de indivíduos ainda vivem sem o acesso à água potável e saneamento gerenciados de maneira segura, embora o direito a esses serviços esteja estabelecido há muito tempo como um direito humano. A questão da água é de interesse global e à medida que muitos dos Objetivos de Desenvolvimento Sustentável estão atrasados, o avanço na realização do ODS 6 é de suma importância para o êxito dos demais objetivos. O estudo concentra-se na Década Internacional da Água (2018-2028), ao analisar elementos que moldam políticas públicas e o controle social na gestão de recursos hídricos. Uma análise bibliográfica exploratória foi conduzida, destacando a importância da participação da sociedade civil para atingir as metas estabelecidas. A pesquisa evidenciou que a Década é vista como um catalisador para o compartilhamento de boas práticas e formação de parcerias, fortalecendo a gestão hídrica e alcance dos ODS.
Sobre instituições e o serviço social em contexto de crise do capital
Authors: Dahmer Pereira Tatiana
Published: January 2024

O texto consiste em reflexão teórica, a partir de pesquisa bibliográfica. Versa sobre a formação das instituições no Brasil, com suas determinações colonialistas e de raízes escravistas, como pressupostos analíticos para a construção de atuação crítica do Serviço Social nestes espaços. Considera a distinção entre como se constituem e como aparentam – na medida em que as instituições aparecem, na modernidade, como algo impessoal, perene e mediador de relações sociais, expressando pactuação necessária à vida em sociedade. Na conformação da sociabilidade burguesa emergem como instâncias que anunciam previsibilidade, ordenamento e proteção àqueles que vivenciam o processo civilizatório moderno. Porém, escamoteiam violências e mecanismos de reprodução de relações sociais de opressão e desigualdade inerentes ao movimento histórico de valorização do capital.
Military construction and military duty in Dagestan in 1928–1940: a historical and socio-cultural aspects
Authors: Kaymarazov G. Sh. , Kaymarazova L. G.
Published: January 2024

The article considers the historical and socio-cultural aspects of military development in the Dagestan Autonomous Soviet Socialist Republic from 1928 to 1940, taking into account the growing interest in society and the scientific community in military history, including the problem of involving the peoples of national regions of the country in the process of formation and further development of the Soviet Armed Forces. In the research the principles of historicism, scientific objectivity, as well as comparative historical, problem-chronological, statistical and descriptive methods have been used; new publications and documentary sources that have not previously been introduced into scientific circulation have been employed.

The historical and social and cultural aspects of military development in the Dagestan Autonomous Soviet Socialist Republic from 1928 to 1940 have been considered. - from the moment of the first compulsory conscription of Dagestanis for military service in the ranks of the Workers 'and Peasants' Red Army (RKKA) until the adoption in September 1939 by the Supreme Soviet of the USSR of the new Law “On General Military Duty”. This event marked the beginning of the implementation of military service by representatives of the male youth of the peoples of Dagestan service on a common basis with all nationalities of the USSR.

The research characterizes the work of the authorities to establish military registration of the male part of the population and pre-conscription training of young people in a multinational region. The gender component of the process of formation of military service has been highlighted; the features of the implementation of Soviet military construction in Dagestan within the designated chronological framework identified and prospects and scope of application of the research results characterized.
Рpinciples of developing the russian cultural identity of university students in foreign language classes
Authors: Ryapolova N. V.
Published: January 2024

Relevance. In the context of increasing geopolitical tensions in the world the development of Russian cultural identity of students in foreign language classes is of particular importance. Modern Russian society needs competent, creative and active specialists, whose training will not be relevant and sufficient without acquiring knowledge not only about the culture of the countries of the language being studied, but also about their own culture. In the current situation, a foreign language has priority importance as a means of intercultural communication and generalization of the spiritual heritage of the countries and peoples of the studied and native languages.

The Research problem: what are the principles of development of Russian cultural identity that contribute to the formation of foreign language communicative competence? The purpose of the research is to substantiate the implementation of the principles of development of Russian cultural identity of technical university students in foreign language classes that contribute to the formation of foreign language communicative competence. The research methods used include pedagogical observation, study of psychological and pedagogical literature, retrospective analysis of teaching activities, assessment, study of the work experience of teachers of higher educational institutions. The results of the research are the following: the role of a foreign language in the formation of Russian cultural identity of students has been determined; principles for the development of Russian cultural identity of students in foreign language classes at a university have been formulated and examples of their implementation given. Key conclusions: the principles of ethnocultural orientation of teaching and the use of PR technologies in foreign language classes, the purpose of which is the development of the Russian cultural identity of students at a technical university, contribute to the formation of foreign language communicative competence.
Education for citizenship as a scientific problem
Authors: Putilov E. V.
Published: January 2024

The Russian society is characterized by the process of forming a new system for educating the younger generation, the core of which is the development of an active citizenship position. The global geopolitical situation poses a whole range of tasks for the education system related to the development of new content of education based on deepening civil law education. Therefore, recently in domestic Pedagogy a certain strategic guideline has emerged for studying issues of civic-patriotic education of the younger generation.

The problem of the research is to substantiate the features of education for citizenship in modern scientific and pedagogical research. Solving this problem is the goal of our research.

The methodological basis of the research is based on socio-pedagogical concepts of civic education, the use of scientific methods (theoretical analysis of scientific literature, normative documents, products of teachers’ activities; descriptions; interpretation; generalizations).

The research results: conceptual models of citizenship in some countries have been described; the essence of the phenomenon «Russian patriotism» has been revealed; aspects of citizenship education in modern pedagogical discourse have been outlined.

Key conclusions: 1) in the scientific literature, four models of citizenship have been revealed: American, British, German and Russian; 2) the core of the concept of «citizenship» is the presence among citizens of a particular country of a number of personal qualities as personal results of educational activities; 3) the pedagogical content of citizenship is associated with the justification of this term as a subject of educational activity; highlighting the totality of civic qualities as personal results of educational activities; creation of a nurturing educational environment; teachers’ possession of the necessary competencies that allow them to carry out this work
Using an educational method according to special exercises to perform the skill of bow and develop flexibility for cub wrestlers in Iraq
Authors: Mohammed Khalid Awad  , Khulood Juma Qasim  , Shaima Habib Ali
Published: January 2024

creating unique exercises utilizing a teaching approach that works with the research sample, determining how special exercises affect the development of torso flexibility, and determining how special exercises affect the development of bow ability. Activate the search The results of the pre- and post-tests for the control and experimental research groups show a statistically significant association that is favoring the post-test in the development of bow skill performance Using the experimental technique, the researcher set up one group and gave them two tests (pre and post) based on scientific theories that made sense for the topic at hand. Forty adolescent wrestlers from the Adhamiya Club in the Baghdad Governorate were recognized by the researcher. The researcher selected, at a ratio of 20, an age group consisting of only those between the ages of 12 and 14. 50% are wrestlers of the research's initial population. In terms of gathering data, the researcher employed the intended approach—the stretcher. Because the created educational technique is simple to use and produces accurate numerical results, the researchers came to the conclusion that it has demonstrated its potential to increase the flexibility of the thoracic muscles. The study suggests that sports clubs incorporate instructional techniques into their training programs.