bluuebunny/crossref_metadata_2025 huggingface dataset:
Determining Polycyclic Aromatic Compounds in Bird Feathers Using Pressurized Fluid Extraction
Authors: Moradi Vida , Halldorson Thor , Xia Zhe , Vitharana Nipuni , Marvin Chris , Thomas Philippe J. , Sorais Manon , Crossin Glenn T. , Tomy Gregg
Published: September 2023

Due to their ease of collecting and transporting from the field and their ability to accumulate pollutants, bird feathers are increasingly being used as a non-invasive biomonitoring tool for environmental monitoring programs. Polycyclic aromatic compounds (PACs) are a diverse class of environmental pollutants, and because of their deleterious impacts on biological species, monitoring these compounds in wildlife is of high importance. Current approaches to measuring PACs in bird feathers involve a time-consuming acid treatment with a concomitant solvent extraction step. Here, a validated method for measuring a suite of PACs in bird feathers using pressurized fluid extraction and identification and quantitation by gas chromatography-tandem mass spectrometry is presented. Chicken (Gallus domesticus) feathers were purposely fortified with a suite of 34 PACs separately at three fortification levels and placed inside a pressurized fluid extraction cell containing silica gel/deactivated alumina to provide in situ clean-up of the sample. Except for anthracene and naphthalene, the accuracy of our method ranged for PAHs from 70–120% (irrespective of fortification level), and our intra- and inter-day repeatability was smaller than 28%. For APAHs, our accuracies ranged from 38–158%, and the inter- and intra-day repeatability was less than 35%. Our limits of detection and quantitation for both groups of compounds ranged from 0.5–13 and 1.5–44.3 ng/g, respectively. Overall, the developed method represents an effective and efficient approach for the extraction and quantitation of PACs from bird feathers that negated the need for the time-consuming and potentially harmful acid treatment.
Comparative Study on National Policies and Educational Approaches toward Regional Revitalization in Japan and South Korea: Aiming to Achieve the Sustainable Development Goals
Authors: Osanai Shiori , Yu Jeongsoo
Published: September 2023

Declining birthrates and aging populations are progressing globally, but this trend is particularly prominent in East Asia. Japan and South Korea face SDG-related problems, such as declining birth rates, aging populations, and depopulation in rural areas due to population concentration in urban areas. In this study, “regional revitalization” was set as a keyword for solving SDG-related issues in Japan and South Korea to conduct a comparative analysis of the relevant trends and characteristics of national policies and educational approaches in Japan and South Korea through a literature review. A comparative analysis of the policies and educational approaches to regional revitalization in Japan and South Korea reveals that policies and education are closely related to regional revitalization. Japan aims to increase the permanent population of young people through creating attractive regions in each region, and South Korea aims to alleviate the labor shortage caused by the declining population with labor immigration and aims for regional revitalization via comprehensive cooperation among its own citizens, immigrants, and people with multiple cultures.
Cross-Cultural Mobility and Agency in Assessing the Appropriateness of Child Supervision in the Context of Cultural Diversity and Migration in Quebec
Authors: Ruiz-Casares Mónica , Sullivan Richard , Gonzalez Emilia , Li Patricia , Lacharité Carl
Published: September 2023

Confusion over what constitutes appropriate childrearing practices in culturally diverse settings may result in the stigmatization of ethnic minority families and over-reporting to child welfare services. This study explored stakeholders’ views on (in)adequate supervision across cultural and socioeconomic groups and how they assess the risk of harm in cases of lack of supervision. Focus group discussions were held with (a) adult caregivers (n = 39) and adolescents (n = 63) in family-based care from French-speaking Quebecers and migrants from Latin America, the Caribbean, and South Asia; and (b) professionals (n = 67) in the education, health, child welfare, and security sectors in Quebec. The main criteria used to assess the appropriateness of supervision were the maturity, level of ability, age, and sex of the child, as well as contextual factors, such as proximity of other people, location, and type and duration of the activity. Mobility and immobility notions are used to explore the developmental considerations of competence and readiness within the home and in other social environments where adults’ and children’s perceptions of safety and maturity may differ, as well as the need to move away from rigid policy implementation. This paper advocates for careful consideration of the capacity and agency of children affected by migration in the provision of childcare support and their meaningful participation in research and decision making in matters that affect them.
Spatiotemporal Patterns and Driving Factors of Non-Grain Cultivated Land in China’s Three Main Functional Grain Areas
Authors: Zhao Suxia , Xiao Dongyang , Yin Mengmeng
Published: September 2023

Food security, fundamental to national security, is challenged by the non-grain conversion of cultivated land. Based on the social and economic statistical data in China, this paper explores the spatiotemporal patterns and driving factors of non-grain cultivated land nationwide and in China’s three main functional grain areas during 2000–2020 with the help of the GIS Spatial Analysis and Spatial Metrology Model. The results show, first, that non-grain conversion initially increased but later decreased, with the non-grain level increasing from 30.61% in 2000 to 34.78% in 2003 and then decreasing to 30.28% in 2020; vegetables, fruits, and medicinal herbs were the main non-grain crops in most areas. Second, the non-grain levels showed an obvious spatial agglomeration state; the regions with low non-grain levels were located in the main grain-producing areas, and although the non-grain conversion levels in the main grain-producing areas decreased, the non-grain levels in these areas were clearly lower in the north than in the south. Moreover, the non-grain conversion levels in the main grain-sales areas and the grain production and sales balance areas increased. Third, rural population size, per capita GDP, the proportion of primary industry, and the land transfer rate are important drivers of the non-grain conversion of cultivated land nationally, but there are also significant spatial differences in the influence of these driving factors in different functional grain areas. This paper provides a new research perspective for analyzing the influencing mechanisms of cultivated non-grain land from the three functional grain areas. At the same time, it reveals the roots of the government’s predicament in the governance of non-grain cultivated land. It provides a reference for the government to formulate new policies for managing non-grain cultivated land.
SSUIT Smart Sustainable Urban Infrastructure Transitioning
Authors: Geldenhuys Heinrich Jacques , Brent Alan Colin , De Kock Imke Hanlu
Published: September 2023

Transformation towards smart sustainable cities requires transitioning and modernising urban infrastructure systems. This study builds upon previous work and recommendations to address the need for a holistic and comprehensive framework to guide the planning, development, and management of smart sustainable infrastructure transitions. Existing approaches and methods regarding city and infrastructure transitioning were reviewed to draw up an understanding of, the requirements for, and guidelines useful to the design of a conceptual framework. The framework was established through synthesis of the knowledge and insight gathered from the literature. A collective case study analysis was used to verify the theoretical framework and make adaptations to successfully address any shortcomings. The framework was then also subjected to a validation process testing the appropriateness of the framework’s design using a Delphi technique and industry experts. After adapting the framework based on the feedback from experts, all of them were certain the framework would hold up in practice. The framework is intended as a generic guideline useful to municipal managers, city planners, and project portfolio managers appointed to plan, direct, and manage the transition of an existing city towards a smart sustainable city.
Characteristics and Variations in Korea through the Lens of Net-Zero Carbon Transformation in Cities
Authors: Duan Ziyu , Kim Seiyong
Published: September 2023

As climate issues become more severe, the necessity and importance of urban transformation are being widely recognized, and the breadth and depth of research in various disciplines of social sciences to promote net-zero carbon (NZC) transformation in cities is increasing. In this study, between 2015 and 2021, 17 major cities and administrative regions in Korea from were taken as the target and based on the driving force-pressure-state-impact-response (DPSIR) model, a framework of 23 indicators of energy, environment, and economic systems (3ES) was constructed through the coupling coordination degree (CCD) assessment system. The development level, development speed, coordination index of subsystems, and coupled coordination relationship were analyzed successively. Finally, a gray correlation model was adopted to extract the 3ES of each city and their key driving factors. The findings indicate that: (1) There is a phenomenon of high coupling and low coordination within the subsystem, with the environmental factors layer being the most critical concern. (2) The overall coupling of the system has improved continuously since 2015, but it is still at the moderate coupling stage, owing to the long-term nature of system contradictions and processing lags. (3) The driving causes of urban transformation have shifted from economic to environmental restrictions, resulting in noticeable regional differences later in the study period and a rise in the necessity for hierarchical zoning governance. Finally, based on the perspective of restricted subsystems and the consolidation of the 3ES coordination relationship, this study demonstrates the significant relationship between environmental protection, energy transition, and economic development, thus enriching the associated literature at the periphery. It also provides a theoretical foundation for investigating the transition path of NZC cities, thus enhancing research in this area.
Does Environmental Labelling Still Matter? Generation Z’s Purchasing Decisions
Authors: Kabaja Bartłomiej , Wojnarowska Magdalena , Ćwiklicki Marek , Buffagni Stefania Claudia , Varese Erica
Published: September 2023

This research paper explores the role of environmental labelling in shaping the purchasing and consumption behaviours of Generation Z. The study aims to provide insights into the comprehension, perception, and attitude of this generation towards environmental labelling and to investigate how these factors impact their purchasing decisions. The results of this study provide valuable insights into the role of environmental labelling in shaping the behaviours of young consumers and suggest that it still matters to this generation. The study also highlights the importance of trust in environmental labelling for influencing purchasing decisions. Our research paper provides new insights into the role of environmental labelling in shaping the behaviours of Generation Z, which is a critical demographic group for sustainable consumption. We found that this generation is highly aware of environmental issues and is motivated to make eco-friendly purchasing decisions. However, our study also highlights that the lack of trust in environmental labelling can be a significant barrier to sustainable consumption. This study contributes to the literature on environmental labelling and consumer behaviour among Generation Z.
Environmental Impact Evaluation as a Key Element in Ensuring Sustainable Development of Rail Transport
Authors: Milewicz Julia , Mokrzan Daniel , Szymański Grzegorz M.
Published: September 2023

The development of railways stands as a pivotal milestone in the history of transportation, transforming the world and revolutionising the movement of people and goods. From their humble beginnings as rudimentary track systems to the sophisticated and interconnected networks we witness today, railways have played a crucial role in fostering economic growth, promoting globalisation, and shaping modern societies. Moreover, as the world grapples with the urgent need to mitigate climate change and transition to sustainable modes of transportation, the role of railways has gained significant attention. Railways have long been recognised as one of the most environmentally friendly means of mass transit, offering lower carbon emissions, energy efficiency, and reduced congestion compared to other transportation modes. However, there are still many challenges to overcome to provide continuous sustainability in the context of environmental impacts, especially related to wildlife and habitat protection. This scientific paper aims to explore the concept of sustainability in the context of railways, providing a comprehensive analysis of their environmental influences. As a result, the authors present a complex analysis of the topic, combining different perspectives—ecological, engineering, and legislative. They present methods of reducing noise pollution—constructional and legal ways; emission pollution reduction associated with combustion engines; and innovative analysis of limiting the impact of transportation on natural habitats and forest animal populations, which is not yet sufficiently elaborated scientifically in the literature. By examining key strategies, technologies, and policy frameworks, this research sheds light on the challenges and opportunities related to sustainability within the railway industry around the world.
Leading the Circular Future: South Australia’s Potential Influence on Circular Economy Development in Asia-Pacific Region
Authors: Devlin John , Hopeward Keri , Hopeward James , Saint Christopher
Published: September 2023

Circular economy is among the most influential concepts relating to the realization of Agenda 2030 and the Sustainable Development Goals. Advocates of the circular economy promote its potential to achieve a decoupling of growth from material consumption. Academic critiques describe the circular economy concept as poorly defined and insufficiently concerned with other problems associated with consumerism, globalization, and inequality. South Australia has built a reputation as a first mover in waste management regulations and has recently positioned itself as a leader in the transition to the circular economy. However, the Asia-Pacific region contains a wide variety of socioeconomic, geographic, and climatic conditions that impact waste generation, resource recovery, and circular economy potentials. There are questions about the appropriateness of transferring waste strategy and technologies to different settings. Therefore, this paper explores the basis of South Australia’s leadership credentials and discusses its potential influence over the region. This research is based on an analysis of policy documents produced by the South Australian Government. This study found that while multiple South Australian policy documents highlight a desire to lead in circular economy transition, South Australia’s leadership reputation had been built prior to its adoption of circular economy ideology. The South Australian Waste Strategy 2020–2025 projects a vision of circular futures aligned to circular modernism and planned circularity. The paper concludes that any transfer of waste strategy should occur with sensitivity to existing waste management systems including the informal sector. Asia-Pacific countries, including Australia, should consider decentralized, low-tech circular economy projects to help to achieve the Sustainable Development Goals.
Elevating B2B Mobility with Sharing Autonomous Electric Vehicles: Exploring Prerequisite Criteria and Innovative Business Models
Authors: Chirumalla Koteshwar , Klaff Sara , Zako Rania , Sannö Anna
Published: September 2023

The transition towards a circular economy compels manufacturing companies in the transportation industry to reassess how they create, deliver, and capture value for their customers. Autonomous electric vehicles, with their advanced connectivity, autonomy, and efficiency, offer innovative business opportunities and services. However, there is limited knowledge concerning the sharing of autonomous electric vehicles in the business-to-business (B2B) market, particularly for industrial manufacturing companies. This study aims to identify the prerequisite criteria and potential innovative business models for sharing autonomous electric vehicles within a B2B context. To investigate this phenomenon, the study employs a case study approach within the heavy-duty vehicle industry, which involves a vehicle manufacturer and customers from a specific industry sector. The findings reveal that economic gain, service quality, and accessibility serve as prerequisite criteria for sharing autonomous electric vehicles in a B2B context. Furthermore, by leveraging a morphological framework, the study outlines five business model scenarios to explore the potential of sharing autonomous electric vehicles in enhancing B2B mobility. This research contributes to the field of business model innovation in a B2B context by introducing a model that delineates both the prerequisite criteria and potential business model concepts for the B2B sharing of autonomous electric vehicles.
One-Class Machine Learning Classifiers-Based Multivariate Feature Extraction for Grid-Connected PV Systems Monitoring under Irradiance Variations
Authors: Yahyaoui Zahra , Hajji Mansour , Mansouri Majdi , Bouzrara Kais
Published: September 2023

In recent years, photovoltaic (PV) energy production has witnessed overwhelming growth, which has inspired the search for more effective operations. Nevertheless, different PV faults may appear, which leads to various degradation stages. Furthermore, under different irradiance levels, these faults may be misclassified as a healthy mode owing to the high resemblances between them, thus provoking serious challenges in terms of power losses and maintenance costs. Hence, interposing the irradiance variation in grid-connected PV (GCPV) systems modeling is important for monitoring tasks to ensure the effective operation of these systems, to increase their reliability and to prevent false alarms. Therefore, in this paper, a fault detection and diagnosis (FDD) method for the GCPV systems using machine learning (ML) based on principal component analysis (PCA) is proposed in order to ensure the reliability and security of the whole system under irradiance variations. The proposed strategy consists of three main steps: (i) introduce the irradiance variations in PV system modeling because of its great impact on power production; (ii) feature extraction and selection through PCA; and (iii) fault classification using ML techniques. In this study, we generate a database that is used to compare the proposed strategy with the standard strategy (considering a fixed irradiance during FDD), to make, at first, a complete and significant comparative assessment of fault diagnosis and to demonstrate the efficiency of the proposed strategy. The achieved results show the high effectiveness of the proposed one-class classification-based approach to detect and diagnose PV array anomalies, reaching an accuracy up to 99.68%.
The Market Responses of Ice and Snow Destinations to Southerners’ Tourism Willingness: A Case Study from China
Authors: Sun Kun , Tian Xiaoli , Xia Jing , Ou Mian , Tang Chengcai
Published: September 2023

Since the 2022 Beijing Winter Olympics, China has been promoting ice and snow tourism, mainly to domestic tourists from southern China. Thus, ice–snow tourism operators in the north need to know what Southerners want. Respondents from south of the Yangtze River in Jiangsu Province were administered a questionnaire about candidate national parks in Inner Mongolia as tourism destinations. A qualitative method based on picture material was used to summarize the categories of ice–snow tourism activities. Based on questionnaire data by OLS (ordinary least squares) and quantile regression, respectively, this study identified the average and differential (by the difference of respondents’ willingness level) inducing effects of different tourism activities on Southerners’ ice–snow tourism willingness. With the supply–demand comparing method, the impacts of the tourism activity availability on the fulfillment of Southerners’ ice–snow tourism desire were revealed. For formulating sound market positioning to expand the southern market, suggestions for promoting the preferred activities and complementing the supply shortage were put forth based on Southerners’ willingness. The results provide meaningful lessons for developing, operating, and marketing ice–snow tourism destinations in the north in response to Southerners’ willingness to travel.
Extended Overnight Monitoring of Respiratory Events after Bariatric Surgery
Authors: Popiolek Christopher , Melloni Giorgio , Balouch Maha , Mooney Ashley , DuCoin Christopher , Docimo Salvatore , Camporesi Enrico
Published: September 2023

Introduction: Patients receiving bariatric surgery are at risk for sleep apnea (OSA) and need extensive surveillance in the postoperative period. There is evidence of respiratory events (RE) several hours after leaving PACU. We analyzed the late onset of RE in patients recovering from bariatric surgery and their opiate requirements through the first night after surgery. Methods: We studied 52 patients with OSA and 38 non-OSA patients. Preoperative studies comprised meticulous OSA evaluation for all patients and computing the predictive score PRODIGY to stratify for the risk of RE. All patients received intraoperative multimodal non-opioid anesthesia. After PACU recovery, patients were admitted to a ward and continuously monitored for pulse oximetry, heart rate, and acoustic respiratory rate for up to 18 h using MASIMO RAD-97 and TRACE software (Masimo, USA). Results: All patients showed a progressing reduction in the frequency of RE after admission to the floor. Desaturations and bradypnea, however, increased significantly for a second peak between 14 and 16 h in the OSA group. The opiate doses administered to OSA and non-OSA patients were not different and remained low during the increases in RE. Discussion: After bariatric surgery, patients with OSA show significant late-desaturation and bradypnea events. Opiate administration cannot be invoked as the cause.
Boundedness in the Bloch Space of Symmetric Domain for a Class of Multi-Valent Meromorphic Functions Given by a Fractional Integral
Authors: Aldawish Ibtisam , Ibrahim Rabha W.
Published: September 2023

Convolution operators have profited in various areas of science. They are utilized in the investigations of computing techniques. A new convolution operator linked to a specific class of multi-valent meromorphic functions in the punctured unit disk (symmetric domain) is formulated. This analysis uncovers certain properties on the connections as well as the power series. We study a novel class of holomorphic functions concerning the recommended new operator. The second part of the outcome concerns the boundedness of the suggested difference structure given by the proposed operator. We focus on the Bloch space of meromorphic functions in the open unit disk. In this case, we use the spherical derivative. To obtain the maximum value of the polar derivative of the polynomials created by their partial sums, we use their partial sums as applications of the suggested operator.
The Solution of Coupled Burgers’ Equation by G-Laplace Transform
Authors: Alhefthi Reem K. , Eltayeb Hassan
Published: September 2023

The coupled Burgers’ equation is a fundamental partial differential equation with applications in various scientific fields. Finding accurate solutions to this equation is crucial for understanding physical phenomena and mathematical models. While different methods have been explored, this work highlights the importance of the G-Laplace transform. The G-transform is effective in solving a wide range of non-constant coefficient differential equations, setting it apart from the Laplace, Sumudu, and Elzaki transforms. Consequently, it stands as a powerful tool for addressing differential equations characterized by variable coefficients. By applying this transformative approach, the study provides reliable and exact solutions for both homogeneous and non-homogeneous coupled Burgers’ equations. This innovative technique offers a valuable tool for gaining deeper insights into this equation’s behavior and significance in diverse disciplines.
Ameliorative Effect of Thymoquinone and Thymoquinone Nanoparticles against Diazinon-Induced Hepatic Injury in Rats: A Possible Protection Mechanism
Authors: Nassar Walaa M. , El-Kholy Wafaa M. , El-Sawi Mamdouh R. , El-Shafai Nagi M. , Alotaibi Badriyah S. , Ghamry Heba I. , Shukry Mustafa
Published: September 2023

The health benefits of thymoquinone (TQ) have been a significant focus of numerous studies. However, more research is needed to ascertain whether its nano-form can effectively treat or prevent chronic diseases. In this study, we investigated how thymoquinone and its nanoparticles can mitigate liver damage induced by diazinon in male Wistar rats and explored the intracellular mechanisms involved. Forty-two Wistar male rats (n = 42) were randomly allotted into seven groups. Group 1 served as the control. Group 2 (vehicle) consisted of rats that received corn oil via a gastric tube daily. In Group 3 (TQ), rats were given a daily oral administration of TQ (40 mg/kg bw). Group 4 (thymoquinone nanoparticles, NTQ) included rats that received NTQ (0.5 mg/kg bw) orally for 21 days. Group 5 (DZN) involved rats that were administered diazinon (DZN, 15 mg/kg bw) orally. In Group 6 (TQ + DZN), rats first received TQ orally, followed by DZN. Group 7 (NTQ + DZN) consisted of rats receiving NTQ orally, then DZN. After 21 days of treatment, the rats were euthanized. After oral administration of DZN, liver enzymes were significantly elevated (p < 0.05). Additionally, there were noticeable increases in oxidative injury markers, such as nitric oxide, malondialdehyde, redox oxygen radicals, and overall increases in hydrogen peroxide and liver protein carbonyl concentrations. This was accompanied by the upregulation of apoptotic markers (Bax, caspase9, caspase 3, bax/Bcl2 ratio), inflammatory cytokines (TNF-α, IL-6), and DNA damage. There was also a noteworthy decrease (p < 0.05) in the activities of antioxidant enzymes and anti-apoptotic markers. However, the oral administration of thymoquinone or its nanoparticle form mitigated these diazinon complications; our histopathological findings corroborated our biochemical and molecular observations. In conclusion, the significant antioxidant properties of thymoquinone, or its nanoparticle form, in tandem with the downregulation of apoptotic markers and inflammatory cytokines, provided a protective effect against hepatic dysfunction caused by diazinon.
Implementation of a Community-Based Public Model for the Prevention and Control of Communicable Diseases in Migrant Communities in Catalonia
Authors: Gómez i Prat Jordi , Alguacil Helena Martínez , Pequeño Saco Sandra , Ouaarab Essadek Hakima , Montero i Garcia Jordi , Catasús i Llena Oriol , Mendioroz Peña Jacobo
Published: September 2023

In high-income countries, migrant populations have a greater epidemiological vulnerability: increased exposure to infectious diseases, difficulties in diagnosis, case follow-up and contact tracing, and obstacles following preventive measures related to cultural and administrative barriers. This study aims to describe the implementation of a community-based program to address these challenges. The target population is the migrant native population from North Africa, South Asia, Sub-Saharan Africa, Eastern Europe, and Latin America resident in Catalonia during 2023. Implementation phases include the identification of the perceived needs, search, recruitment and capacity building of 16 community health workers, and the development of a computer software. From January to June 2023, 117 community-based interventions have been implemented, reaching 677 people: 73 community case and contacts management interventions, 17 community in-situ screenings (reaching 247 people) and 27 culturally adapted health awareness and education actions (reaching 358 people). The program addresses the following infectious diseases: tuberculosis, Chagas disease, hepatitis C, typhoid, scabies, hepatitis B, mumps and tinea capitis. The implementation of a community-based model may be key to improving surveillance communicable diseases, promoting an equitable and comprehensive epidemiological surveillance system.
Extracellular Vesicles and Their Impact on the Biology of Protozoan Parasites
Authors: Sharma Manu , Lozano-Amado Daniela , Chowdhury Debabrata , Singh Upinder
Published: September 2023

Extracellular vesicles (EVs) are lipid-membrane-bound structures produced naturally by all cells and have a variety of functions. EVs act as vehicles for transporting important molecular signals from one cell to another. Several parasites have been shown to secrete EVs, and their biological functions have been extensively studied. EVs have been shown to facilitate communication with the host cells (such as modulation of the host’s immune system or promoting attachment and invasion into the host cells) or for communication between parasitic cells (e.g., transferring drug-resistance genes or factors modulating stage conversion). It is clear that EVs play an important role in host–parasite interactions. In this review, we summarized the latest research on the EVs secreted by protozoan parasites and their role in host–parasite and parasite–parasite communications.
HPV Vaccination in Immunosuppressed Patients with Established Skin Warts and Non-Melanoma Skin Cancer: A Single-Institutional Cohort Study
Authors: Bossart Simon , Daneluzzi Cloé , Moor Matthias B. , Hirzel Cédric , Heidemeyer Kristine , Seyed Jafari S. Morteza , Hunger Robert E. , Sidler Daniel
Published: September 2023

cSCC (cutaneous squamous cell carcinoma) and its precursors are a major cause of morbidity, especially in immunosuppressed patients, and are frequently associated with human papillomavirus (HPV) infections. The purpose of this study is to investigate the therapeutic potential of alpha-HPV vaccination for immunosuppressed patients with established cSCC and its precursors. In this retrospective study, all patients who received Gardasil-9®, a nonavalent HPV vaccine, as secondary prophylaxis were examined. Dermatologic interventions in both the pre- and post-vaccination periods were analyzed with zero-inflated Poisson regression and a proportional intensity model for repeated events with consideration of the clinically relevant cofactors. The hazard ratio for major dermatologic interventions was 0.27 (CI 0.14–0.51, p < 0.001) between pre- and post-Gardasil-9® intervention. Gardasil-9® vaccination showed good efficacy in reducing major dermatologic interventions even after correction of relevant cofactors and national COVID-19 caseloads during the observational period. Alpha-HPV vaccination may potentially cause a significant decrease in dermatologic interventions and overall mortality as well as healthcare costs in immunosuppressed patients with high skin tumor burden.
A Novel Intelligent Model for Monthly Streamflow Prediction Using Similarity-Derived Method
Authors: Xu Zifan , Cheng Meng , Zhang Hong , Xia Wang , Luo Xuhan , Wang Jinwen
Published: September 2023

Accurate monthly streamflow prediction is crucial for effective flood mitigation and water resource management. The present study proposes an innovative similarity-derived model (SDM), developed based on the observation that similar monthly streamflow patterns recur across different years under comparable hydrological and climate conditions. The model is applied to the Lancang River Basin in China. The model performance is compared with the commonly used support vector machine (SVM) and Mean methods. Evaluation measures such as RMSE, MAPE, and NSE confirm that SDM6 with a reference period of six months achieves the best performance, improving the Mean model by 79.9 m3/s in RMSE, 6.07% in MAPE, and 8.62% in NSE, and the SVM by 53.65 m3/s, 0.24%, and 5.53%, respectively.
Gender-based patterns of language use : the case of Dakar
Authors: Swigart Leigh
Published: September 2023

L'étude des choix linguistiques et des attitudes de Dakarois ayant au moins une connaissance du wolof et du français, examine comment ceux-ci se situent dans leur univers socio-linguistique, d'une génération à l'autre, d'un sexe à l'autre. Le wolof urbain, un code-swithching de wolof et de français au niveau intra-phrastique, fonctionne comme code non marqué dans de nombreux contextes, informels surtout, pour des bilingues équilibrés.

L'enquête auprès de 35 sujets étudiés en profondeur révèle que les femmes sont plutôt conservatrices : elles parlent wolof davantage que français, et leur wolof urbain est moins influencé par le français que celui des hommes. Et, si certaines jeunes femmes -les disquettes -font de l'usage du français la clé pour entrer dans un autre groupe socio-économique que le leur, cette innovation, qui est un choix marqué pour leur sexe, n'est pas généralisée. L'examen du répertoire linguistique (wolof, français et wolof urbain) selon le sexe et l'âge indique en effet que l’avenir linguistique se situe plutôt du côté du wolof urbain. A la différence de ses aînés, la jeune génération est constamment exposée au français. Cependant les jeunes hommes, soumis à une pression de leurs pairs afin d’éviter trop de français, n'ont pas de variété "pure" du wolof à leur disposition et sont les locuteurs par excellence du wolof urbain. Les jeunes femmes, par contre, représentent le dernier groupe à Dakar à parler un wolof plus "pur" avec quelque facilité, du fait d'un contact domestique fréquent avec leurs aînées ; elles tentent souvent de se corriger, même entre elles, lorsqu'elles utilisent la forme mixte. La pression sociale est inverse. Mais, quoique capables de recourir à un wolof plus "pur", elles ne se contrôlent pas constamment et transmettent involontairement à leurs enfants des emprunts au français qui feront donc partie de leur première langue. Entre le français à l’école et le wolof urbain à la maison, ces enfants ne seront plus exposés à la variété plus profonde du wolof.
Fonctions du langage et discours mixte : remarques sur l'alternance français-wolof
Authors: Ndao Papa Alioune
Published: September 2023

A partir de l'analyse de deux dialogues où les locuteurs sont dans un rapport de rôles différent (entre pairs, entre un supérieur et son subordonné), on dresse un inventaire des énoncés constitutifs du discours mixte. L’examen de ces énoncés est d'ordre syntaxique et rhétorique. Il tente de délimiter les principales fonctions (au sens de R. Jakobson) qui régissent leur génération en français, en wolof, ou en discours mixte. Si l’usage des unités wolof marque l'objection et l’assertion catégorique, celui des unités en français signale une argumentation. Dans le discours mixte par contre, les unités wolof ont une valeur expressive, tandis que les unités en français expriment un contenu notionnel. On s'intéresse donc, d'une part, aux modalités stylistiques de la génération des énoncés, d'autre part, aux différentes fonctions socio-symboliques qui leur confèrent la valeur d'attribut de rôle.
Genotype and Phenotype Analysis Using a Hyperlipidemia-Associated Gene Panel in Turkish Dyslipidemia Patients
Authors: GÜN BİLGİÇ Dilek
Published: September 2023

Objective: Familial hypercholesterolemia (FH) is one of the most frequent diseases with monogenic inheritance. Numerous genes have been associated with familial hypercholesterolemia and are being investigated by gene panel testing in patients with familial hypercholesterolemia.

Methods: In the present study, 28 patients with FH and some of their parents were evaluated via next-generation sequencing (NGS) using a targeted panel of 32 genes.

Results: Pathogenic or likely pathogenic variants were detected in six patients in the genes LDLR LIPC and CETP.

Conclusion: The genotype-phenotype correlations of these variants were discussed by comparing the clinical findings with the literature.
Efluvio telógeno: uma sequela pos-COVID 19
Authors: De Abreu Marilda Aparecida Milanez Morgado , Do Nascimento Lilian Jabur , De Sousa Adriana Raquel Santos , Alessi Victor Bomfim
Published: September 2023

No final do ano de 2019, o coronavírus 2 da síndrome respiratória aguda grave (SARS-CoV-2) causou a doença de coronavírus 2019 (COVID-19). Embora o COVID19 seja frequentemente associado a doenças respiratórias leves a graves na fase aguda, alguns pacientes que se recuperam do COVID-19 queixam-se de sinais e sintomas dermatológicos, como queda de cabelo. O eflúvio telógeno (ET) é uma forma muito comum de queda de cabelo caracterizada pela perda de cabelo difusa devido à entrada prematura do cabelo na fase telógena. O objetivo deste estudo foi determinar a prevalência de sequelas de eflúvio telógeno causadas pela Covid-19.  Para atingir o objetivo, optou-se por realizar uma revisão sistemática para descrever e sintetizar as evidências disponíveis sobre esse tema e questões de pesquisa na literatura recorrendo a estudos retrospectivos. Relativamente à estratégia de pesquisa foi realizada uma busca, em julho de 2022, utilizando a base de dados PubMed, recorrendo à seguinte sintaxe: telogen effluvium AND COVID-19 AND incidence AND prevalence NOT (Review OR qualitative studies OR theoretical study OR qualitative study). Foi também usado o filtro condicional dos estudos terem sido publicados de 2020 a 2022. A partir da busca realizada foram encontrados 13 artigos, dos quais 6 foram excluídos por consenso dos autores. Na exclusão, utilizaram-se os critérios dos que não apresentaram conteúdos suficientes para colaboração neste trabalho (N=4), por se tratarem de artigos eminentemente teóricos (N=2) e por não apresentarem os dados epidemiológicos referentes às prevalências das variáveis objeto deste estudo. Após os procedimentos metodológicos anteriormente descritos foram selecionados 07 artigos para revisão sistemática. A grande maioria dos estudos documentou altas taxas de eflúvio telógeno após o Covid-19. A ET é um dos tipos mais comuns de queda de cabelo sem cicatriz, e há dados epidemiológicos muito limitados sobre esse distúrbio. É necessária uma investigação mais aprofundada do ET, como ênfase no tempo de observação e classificação da gravidade do paciente, bem como descrições de achados de especialistas, para padronizar as manifestações cutâneas associadas ao COVID-19.
Trabalho de parto prematuro em hospitais municipais: uma revisão sistemática
Authors: Menezes Armanda Zacarias de Araújo Pessoa
Published: September 2023

O trabalho de parto prematuro (TPP) é um importante desafio de saúde pública em todo o mundo, com consequências significativas para a morbidade e mortalidade neonatal e infantil. Hospitais municipais desempenham um papel crucial no atendimento de gestantes de baixa renda e vulneráveis, muitas das quais estão em maior risco de partos prematuros. Diante desse cenário, esta revisão sistemática teve como objetivo investigar o panorama atual do trabalho de parto prematuro em hospitais municipais e explorar os fatores associados a esse evento. O nascimento prematuro é uma das principais causas de morbimortalidade neonatal. Mais de 50% dos nascimentos prematuros são espontâneos. Os objetivos deste estudo foram predizer fatores de risco para a ocorrência do parto prematuro, estudar inter-relações entre fatores que afetam parto prematuro. O nascimento prematuro refere-se ao nascimento de um bebê que ocorre antes das 37 semanas completas de gestação. O parto prematuro pode ainda ser categorizado como parto prematuro tardio - 34 a 36 semanas completas de gestação, moderadamente prematuro - 32 a 34 semanas completas, muito prematuro - menos de 32 semanas e extremamente prematuro - menos de 28 semanas de gestação. Foi realizada uma análise descritiva sobre o trabalho de parto prematuro em hospitais municipais: uma revisão sistemática, utilizando uma abordagem qualitativa e o método de procedimento de coleta de dados por meio da pesquisa bibliográfica. Conclui-se que o trabalho de parto prematuro continua sendo uma preocupação em hospitais municipais, afetando uma proporção significativa de gestantes atendidas nessas instituições. Diversos fatores de risco foram identificados, incluindo idade materna, baixo índice de massa corporal, infecções genitais, fatores socioeconômicos e comportamentais, entre outros. Além disso, a falta de acesso adequado a cuidados pré-natais de qualidade e intervenções adequadas foram apontados como fatores contribuintes para o aumento das taxas de TPP nesses cenários.
Relação entre tempo de tela e Transtorno do Espectro Autista na faixa pediátrica: uma revisão de literatura
Authors: Parra Camila Abdel Fattah , Bertholino Gabriel Magalhães , Parra Caroline Abdel Fattah , Sartori Felipe Augusto , Ogando Guilherme Pena , Scarpinelli Jaqueline , Silva Amanda Moraes , Devito Eduardo Dias
Published: September 2023

O Transtorno do Espectro Autista (TEA) promove déficits no processo de comunicação da criança podendo promover atrasos no desenvolvimento neuropsicomotor dessas. O uso de telas excessivo tem se apresentado como fator intensificador dos sintomas e prejudicador do processo de desenvolvimento desses indivíduos. Objetivos: compreender a relação entre o TEA e o tempo de uso de telas por crianças com esse diagnóstico. Metodologia: Trata-se de uma revisão integrativa na base de dados PUBMED utilizando os descritores “screen time and children and autism spectrum disorder’’para artigos publicados entre 2018 e 2023. Resultados: O tempo de tela é maior em crianças com diagnóstico de TEA e está relacionado a menor desenvolvimento de habilidades comunicacionais e sociais desses indivíduos. O processo de educação continuada dos pais influencia de forma benéfica na redução do uso desses dispositivos. Conclusão: A relação entre TEA e tempo de uso de tela fica evidente tanto no risco de aparecimento desses sintomas, como no prejuízo à falta de estimulação de habilidades da criança. Os pais devem compreender os riscos do uso em excesso dessas ferramentas e estarem atentos aos tipos de conteúdo e ao tempo dedicado a essas atividades.
O impacto da pandemia do novo Coronavírus sobre as cirurgias oncológicas do aparelho digestivo no Espírito Santo
Authors: Felippe Caroline Werneck , Lorenzoni Eduarda Teixeira , Crevelin Rodolfo Barcellos , Frauches Diana Oliveira , Dos Santos Fernando Henrique Rabelo Abreu
Published: September 2023

Objetivo: Analisar o impacto da pandemia de COVID-19 sobre a realização de internações cirúrgicas oncológicas do aparelho digestivo, no Espírito Santo. Método: Estudo descritivo de dados secundários, de domínio público, obtidos no Sistema de Informações Hospitalares do SUS (SIH/SUS) e referentes às internações hospitalares no Espírito Santo entre março de 2019 e fevereiro de 2021, incluindo o procedimento envolvido, a média de permanência hospitalar e a taxa de mortalidade hospitalar. Resultados: Foi evidenciada redução de 11,37% de internações entre os períodos pré-pandêmico e pandêmico avaliados. Entretanto, observou-se aumento da média de permanência, de 4,82 dias para 5,14, e da taxa de mortalidade hospitalar, de 3,77 óbitos por 100 internações para 6 óbitos por 100 internações. Nos dois períodos, predominaram internações para procedimentos clínicos, seguido por procedimentos cirúrgicos terapêuticos e diagnósticos. Em relação às internações cirúrgicas, observou-se total de 194.649, sendo 110.812 de março de 2019 a fevereiro de 2020 e 83.837 entre março de 2020 a fevereiro de 2021. As internações cirúrgicas do aparelho digestivo foram 27.374 no total, sendo 17.306 em pré-pandemia e 10.068 durante a pandemia, com queda de 41,82%. Também foi verificado decréscimo, de 14,97%, nas internações cirúrgicas oncológicas. Em contrapartida, houve crescimento de 7,29% nas internações cirúrgicas oncológicas do aparelho digestivo. Não houve associação entre o coeficiente de incidência mensal de COVID-19 e a frequência mensal das cirurgias nos agrupamentos estudados, total de internações ou taxa de mortalidade (p>0,05). Tal associação ocorreu apenas em relação à média de permanência (p<0,05). Conclusão: No Espírito Santo, durante os dois períodos estudados, houve redução no número de internações cirúrgicas do trato digestivo e nas internações cirúrgicas oncológicas. Em contrapartida, foi evidenciado aumento de 7,29% nas internações cirúrgicas oncológicas do trato digestivo, apesar desse indicador hospitalar ter exibido uma queda em junho de 2020 e posterior ascensão a partir de julho de 2020.
O impacto da hemorragia pós-parto na mortalidade materna: uma revisão da literatura
Authors: Moreira Tulio Vieira , Silva Giovanna Teixeira , Setoguchi Estela Akemi , Rangel Maria Fernanda Santos , Alves Lara Baldanza Mattos , Faleiro Ingrid Beatriz Teixeira , Barbosa Alice Duque , Tristão Larissa Silva
Published: September 2023

A hemorragia pós-parto (HPP) é definida como perda de sangue maior ou igual a 500ml em partos vaginais e maior ou igual 1000ml em cesarianas. Objetivou-se avaliar, por meio de revisão da literatura, seu impacto na mortalidade materna, fatores e condutas associadas. A HPP é uma complicação grave sendo a principal causa de óbito materno, principalmente nas primeiras 24 horas pós-parto. As causas mais prevalentes incluem atonia uterina, lacerações uterinas ou genitais, anormalidades placentárias e coagulopatias. Além disso, mulheres negras e em países em desenvolvimento apresentam maior mortalidade por HPP. A prevenção envolve cuidados pré-natais adequados, identificação e manejo dos fatores de risco, uso de medicações profiláticas para melhorar contração uterina e práticas obstétricas seguras. A identificação e o tratamento da HPP devem ser imediatos com monitoramento e estabilização do quadro, medidas não farmacológicas, farmacológicas e até intervenções cirúrgicas. O tratamento abrange administração de medicamentos para estimular contrações uterinas e para controle hemorrágico, além de técnicas minimamente invasivas, como o balão de tamponamento uterino. Se refratariedade, pode ser necessária até histerectomia. Nessa perspectiva, entende-se a HPP como um fator de grande impacto na mortalidade materna, o qual requer prevenção e tratamento eficazes para a melhora desse importante problema de saúde pública.