bluuebunny/crossref_metadata_2025 huggingface dataset:
Maximum Number of Steps Taken by Modular Exponentiation and Euclidean Algorithm
Authors: Okazaki Hiroyuki , Nagao Koh-ichi , Futa Yuichi
Published: May 2019

In this article we formalize in Mizar [1], [2] the maximum number of steps taken by some number theoretical algorithms, “right–to–left binary algorithm” for modular exponentiation and “Euclidean algorithm” [5]. For any natural numbers a, b, n, “right–to–left binary algorithm” can calculate the natural number, see (Def. 2), AlgoBPow(a, n, m) := ab
mod n and for any integers a, b, “Euclidean algorithm” can calculate the non negative integer gcd(a, b). We have not formalized computational complexity of algorithms yet, though we had already formalize the “Euclidean algorithm” in [7].

For “right-to-left binary algorithm”, we formalize the theorem, which says that the required number of the modular squares and modular products in this algorithms are ⌊1+log2
n⌋ and for “Euclidean algorithm”, we formalize the Lamé’s theorem [6], which says the required number of the divisions in this algorithm is at most 5 log10 min(|a|, |b|). Our aim is to support the implementation of number theoretic tools and evaluating computational complexities of algorithms to prove the security of cryptographic systems.
Improvement of sperm motility within one month under selenium and vitamin E supplementation in four infertile dogs with low selenium status
Authors: Domosławska Anna , Zduńczyk Sławomir , Janowski Tomasz
Published: May 2019

Introduction: Significant improvement of sperm motility within one month effected by oral supplementation of selenium and vitamin E was described in four infertile male dogs which failed to conceive in their last three matings with different bitches. Material and Methods: The dogs (a Golden Retriever, an English Cocker Spaniel, and two Tibetan Mastiffs) were supplemented daily with selenium (Se) (0.6 mg/kg organic Se yeast) and vitamin E (vit. E) (5 mg/kg) per os for 60 days. Semen was collected on days 0, 30, 60, and 90. The sperm concentration and motility parameters were evaluated by the CASA system, sperm morphology was explored by Diff-Quick staining, and live and dead spermatozoa were differentiated by eosin/nigrosin staining. The concentrations of Se and vit. E were measured in peripheral blood serum on semen collection days. Results: Before administration, the concentrations of Se in blood plasma were low (86.0–165.0 µg/L). After 30 days of treatment there was an observable improvement in total and progressive sperm motility and kinematic parameters (VAP, VSK, VCL, ALH, BCF, and RAPID). The percentages of live and normal morphology sperm cells were also higher. There was also an observable increase in Se and vitamin E concentrations in blood serum. Bitches were successfully mated and delivered four to six puppies. Conclusion: Supplementation with Se and vit. E improved rapid sperm motility and restored fertility in infertile dogs with low Se status.
Talent Management, Employee Recognition and Performance in the Research Institutions
Authors: Masri Nadine El , Suliman Abubakr
Published: May 2019

This paper aims to provide insight into talent management and employee recognition variables, in an effort to understand if these management practices are, in a way, implemented in the Research Institutions in Qatar. It also aims to examine the link of these two constructs to employee performance and to suggest a pathway to improve the current practices, if any, in order to enhance the work performance. The sample of the study consisted of 180 full time employees who were randomly selected and surveyed using an online personalized questionnaire. The results of the empirical research uncover that talent management and employee recognition can significantly affect the level of employee performance, as well contributing to the organizational success and positioning. This study also found that talent management and employee recognition are interrelated variables that affect employee performance. Talent Management and employee performance are seen as strategic tools to implement strategic objectives and to enhance employees and organization’s performance. The study concludes with a set of recommendations for both practitioners and researchers working in Qatar and beyond. The results of the study emphasize the importance of managing employee recognition in shaping work performance. It seems to be individuals’ need for recognition, esteem and social status continues to be a higher order need irrespective of time and context. This paper is the first paper in Qatar and the Middle East that examines the role of talent management and employee recognition in shaping employee performance in the context of research institutions.
Discusiones en torno a una imagen misionera. Nuestra Señora de la Luz y el Cuarto Concilio Provincial Mexicano
Authors: Ratto Cristina
Published: May 2019

In 1771, during the Fourth Mexican Provincial Council, the advocation of Holy Mary Mother of the Light was at the core of a heated debate. Both devotional practices and the widespread circulation of that image, besides treatises on the cult and the arguments of those attending the Council, revealed a complex situation going beyond strictly religious matters. Even though the discussion was around the power images have for “teaching truth” and making “alive that which is certain,” the control on the doctrinal orthodoxy and the devotional practice was aimed at the regulation of the faithful's response when in front of the image. Thus, the statements of advocates and detractors provide grounds for examining the profound interaction between art theory and the theory of the religious image.
Plata y oro para la fe: cultura tridentina e iconología cristiana en la platería neogranadina virreinal
Authors: Guerrero Jiménez Andrea Lorena
Published: May 2019

This article offers a panorama of symbolic relations present in the artifacts of the Neogranadine viceregal silver-smithing, constructed from the research of 106 objects and 48 archive documents. From the vision proposed by John Law and Bruno Latour, the article studies artifacts as “actants,” whose function, form, and materiality constitute semes, identified through iconological and technological footprint analysis. From there, it is possible to unveil the network of connotations that sustained the trade of silver-smithing in the Neogranadine context of the 18th century, that evidences the central role of the Catholic, Baroque, and Counter-Reformation mentality. It also unveils the composition of its imagery in the practices of the silversmiths guild and their clients, which were a reflection of colonial society, where honor derived from devotion was placed before the normative corpus of the Spanish Empire.
Cuerpos sa(n)grados del barroco novohispano
Authors: Rubio de los Santos Mariana
Published: May 2019

This text aims to establish and deploy the body in its concept, which becomes a form in its presentation and representation, delimiting it in specific historical bodies: Baroque sculptures of the body of Christ and the life of the nuns in the female convents during the seventeenth and eighteenth century in New Spain. Using an anthropological methodology, I analyze the relationship between the body and the image. I propose reading the corporeality of the nuns as images created by following a process of assimilation where the sculptures are presented as lacerated bodies. The concept, the form, and the space in which the New Spanish female body unfolds function as axes of argumentation and structure of the text.
El panorama como simulacro. Tecnologías de la mirada colonial en Una holandesa en America (ca.1880), novela ilustrada
Authors: Alzate Carolina
Published: May 2019

This article approaches nineteenth-century visual culture through two artifacts: 1) the panorama, as a practice of modern domestication of nature and bodies; and 2) a novel built with paper and scissors and illustrated with clippings from European press by Soledad Acosta de Samper around 1880. Both are produced at a time when the visual image is particularly relevant and a part of a cultural strategy that, according to Paulette Silva, privileges collection, classification, and exhibition. This article starts with a theoretical approach to panorama, and then examines the way in which it is deployed as a technology of the gaze in Una holandesa en América, an illustrated novel in which the panorama is challenged in its imperial component and then reaffirmed within the creole project of nation building.
De-sacralizando la imagen clerical: salterios y obispos monstruosos en la Inglaterra bajomedieval
Authors: Montero Vallejo Juan Carlos
Published: May 2019

The aim of this article is to identify the political, social, and economic anxieties that prompted East-Anglian secular elites —at the dawn of the fourteenth century— in the commission of private devotional books whose marginalia included, as new and recurrent themes, the monstrous cleric and the monstrous bishop. Establishing a dialogue between documentary sources produced during the period and the close relationship that weaves the texts of the psalter and the visual periphery that used to accompany them, this work suggests that monstrous bishops and clerics expressed the discomfort of East-Anglian lords towards the Avignon Papacy and the disciplinary crisis that faced the English clergy during the thirteenth and fourteenth centuries.
La Anunciación de Carlos Correa: estudio de una polémica en 1942
Authors: Sarmiento Jaramillo Camilo
Published: May 2019

This article reconstructs the controversy that took place in the Third National Exhibition of Artists, 1942, around the artistic work The Annunciation by the painter Carlos Correa. In the first part, we consider the critical precepts that prevailed in Colombia in the first half of the twentieth century through the analysis of two articles: “Rudimentos de estética” (Rudiments of Aesthetics) (1920), by the presbyter Juan Crisóstomo García, and “Del expresionismo como síntoma de pereza e inhabilidad en el arte” (Expressionism as a Symptom of Laziness and Inability in Art) (1937), by the conservative leader Laureano Gómez. The second part reveals how these critical precepts kept operating at the beginning of the 1940s through the examination of a specific case that illustrates the controversial reception of the work indicated in the 1942 exhibition.
Vestigios cifrados: Destrucción, dispersión y reconstitución del patrimonio jesuítico en los Estados de Rio de Janeiro y São Paulo
Authors: Almeida Martins Renata Maria de
Published: May 2019

Many are the mysteries that surround the residual patrimony of the Jesuit missions in Brazil. Due to factors linked to their expulsion from the Portuguese territories (1759), the so-called "spolio" was destroyed, dispersed, and sold, as the inventories show. In this text, we intend to present processes of destruction, dispersion, reconstruction, preservation, and worship that marked the history of the Jesuit heritage in the southeast region of the country, and particularly the Colleges of Rio de Janeiro, São Paulo and the São Paulo coast. Through the study of these cases, it will be possible to demonstrate the meaning of such phenomena for a more accurate understanding of the history of art and architecture of the colonial era in Brazil. Moreover, destruction, preservation, and restoration are options based on criticism and their history will be considered as a document of the ideological and aesthetic postures of Brazilian society.
Dialectical Relationship Between 4Hs (Study-Ask-Understand-Act) and 4Ts (Resonsibility for Oneself, Responsibility for Family, Responsibility for Society, Responsibility for Nature) in Setting an Open Education
Authors: Ai Phu Le
Published: May 2019

Philosophy of education sets out a guideline to an educational system and/or institution. By the philosophy of education, a direction of the educational system and institution is identified. And the philosophy of education itself brings in a basis to define principles of realization as well as to keep all institutional activities in alignment with the philosophy of education. Thus, the philosphy of education is so important and indispensable to an educational system and institution. Moreover, it is the reciprocal relationship between the educational philosphy and its principles which forms up institutional activities in line with the direction set by the educational philosophy. As one of the early tertiary institutions of Binh Duong Province, Binh Duong University provided the province in particular and the country in genral with around 40,000 bachelors, engineers and masters during its 20-year function. One of the factors to account for the school’s success lies in its educational philosphy and follow-up principles upon the basis of 4Hs (study-ask-understand-act) in the process to create responsible citizens of 4Ts (resonsibility for oneself, responsibility for family, responsibility for society, responsibility for nature) towards the open world. As one of the early tertiary institutions of Binh Duong Province, Binh Duong University provided the province in particular and the country in genral with around 40,000 bachelors, engineers and masters during its 20-year function.
Nature Society System Survivability Indicators
Authors: F. Krapivin Vladimir , A. Mkrtchyan Ferdenant
Published: May 2019

The paper gives a description of a global simulation model of the nature-society system evolution when different aspects of the nature and society interactions are taken into consideration. The model structure includes 29 blocks realizing specific restricted operations. Model describes series of important natural and anthropogenic processes including biogeochemical cycles, global hydrologic balance in liquid, gaseous and solid phases, productivity of soil-plant formations with different types defined, photosynthesis in ocean ecosystems, demographic processes, and climate change. One of the main aspects of this model is the estimation of the nature-society system survivability under conditions of limited energy resources. The behavior of nature and society is described by a point in the phase space of the characteristic parameters change of which is determined by the system strategy and behavior. Simulation experiments demonstrate the model functions in framework of serial anthropogenic scenarios.
Pemanfaatan Aplikasi Web dan Mobile sebagai Penunjang Pengurusan Izin Mendirikan Bangunan Kecamatan Baso, Agam
Authors: Akbar Fajril , Wahyuni Alvi Dwi , Kamil Husnil
Published: May 2019

Kecamatan Baso merupakan salah satu kecamatan di Kabupaten Agam Sumatera Barat. Kecamatan Baso diberi wewenang untuk memberikan pelayanan pengurusan Izin Mendirikan Bangunan (IMB) bagi warganya. Dalam proses pelaksanaannya, sistem pelayanan IMB yang sedang berjalan belum optimal. Masyarakat atau pemohon harus berulang kali ke kantor camat untuk mengurus permohonan IMB dan mengecek status permohonannya. Pembuatan dokumen IMB, kwitansi pembayaran, dan rekap laporan pembayaran IMB masih dilakukan dengan cara pengumpulan berkas fisik. Hasil survey lapangan rentan kesalahan dalam perhitungan retribusi karena mash berupa dokumen kertas. Oleh karena itu perlu penerapan otomasi proses dengan komputerisasi dalam proses pengurusan IMB. Penggunaan perangkat lunak berbasis web dan mobile direkomendasikan untuk penyelesaian permasalahan pengurusan IMB di Kecamatan Baso. Metode pengembangan perangkat lunak menggunakan metode waterfall. Beberapa fungsional tersebut diantaranya yaitu dapat mencetak dokumen yang terkait dengan pemrosesan IMB, membuat rekap laporan pembayaran IMB, fitur untuk melakukan survey lapangan ditetapkan sebagai kebutuhan fungsional aplikasi. Sistem dikembangkan dengan model MVC dengan menggunakan Laravel. Pengujian terhadap aplikasi dilakukan secara blackbox testing dan User Acceptance Testing (UAT). Pengujian UAT dilakukan oleh staf kecamatan dan masyarakat. Hasil pengujian blackbox testing didapatkan sistem yang dibangun telah sesuai dengan dengan hasil analisis kebutuhan penggunan.
Ekstraksi Faktor Kompleksitas Game Menggunakan Metode Function Points
Authors: Dewi Renny Sari , Andari Trias Widha , A. Rasyid Maulidan Bagus , Candra A.P. Ramadhany
Published: May 2019

Setelah Presiden Republik Indonesia membentuk Badan Ekonomi Kreatif (Bekraf) dengan Peraturan Presiden (Perpres) No. 6 Tahun 2015, Bekraf berinisiatif untuk mendorong para pelaku bisnis kreatif untuk berkolaborasi dengan pemerintah untuk meningkatkan rekonstruksi negara dari bisnis hiburan ini. Game hari ini telah menjadi sarana pendidikan yang dapat diterima oleh semua kalangan masyarakat. Oleh karena itu, peneliti bertujuan untuk membantu bisnis bidang kreatif digital untuk memperkirakan upaya pengembangan game komputer berdasarkan metode Function Points (FP) yang lebih dikenal sebagai perhitungan biaya proyek pengembangan perangkat lunak aplikasi. Hasil dari penelitian ini adalah kebutuhan untuk memodifikasi pemahaman parameter permainan komputer mulai dari input, output, inquiry, file logika intern, dan extern. Setelah itu, faktor kompleksitas perlu didefinisikan ulang dan disinkronkan dengan delapan item taksonomi LeBlanc. Kemudian, kolaborasinya disebut Game Complexity Factors (GCF). GCF memiliki 22 item faktor kompleks yang terdiri dari 8 taksonomi LeBlanc untuk kesulitan lingkungan dan 14 item kompleksitas teknis.Setelah Presiden Republik Indonesia membentuk Badan Ekonomi Kreatif (Bekraf) dengan Peraturan Presiden (Perpres) No. 6 Tahun 2015, Bekraf berinisiatif untuk mendorong para pelaku bisnis kreatif untuk berkolaborasi dengan pemerintah untuk meningkatkan rekonstruksi negara dari bisnis hiburan ini. Game hari ini telah menjadi sarana pendidikan yang dapat diterima oleh semua kalangan masyarakat. Oleh karena itu, peneliti bertujuan untuk membantu bisnis bidang kreatif digital untuk memperkirakan upaya pengembangan game komputer berdasarkan metode Function Points (FP) yang lebih dikenal sebagai perhitungan biaya proyek pengembangan perangkat lunak aplikasi. Hasil dari penelitian ini adalah kebutuhan untuk memodifikasi pemahaman parameter permainan komputer mulai dari input, output, inquiry, file logika intern, dan extern. Setelah itu, faktor kompleksitas perlu didefinisikan ulang dan disinkronkan dengan delapan item taksonomi LeBlanc. Kemudian, kolaborasinya disebut Game Complexity Factors (GCF). GCF memiliki 22 item faktor kompleks yang terdiri dari 8 taksonomi LeBlanc untuk kesulitan lingkungan dan 14 item kompleksitas teknis.
Pembangunan Auto Backup SQL Database Server Menggunakan Raspberry Pi : Studi Kasus
Authors: Meidelfi Dwiny , Amnur Hidra , Novri Novri
Published: May 2019

Pembangunan auto backup SQL database server bertujuan untuk menutupi kelemahan pada database Server jurusan Teknologi Informasi Politeknik Negeri Padang. Server ini menanggulangi kemungkinan terjadinya kerusakan data, kehilangan data atau kerusakan media penyimpan database. Raspberry Pi adalah mikro komputer yang digunakan sebagai backup server.  Spesifikasi yang minim dapat digunakan secara optimal untuk membangun backup server karena tidak banyak sumber daya yang sia-sia. Backup database dilakukan dengan cara menggabungkan beberapa fungsi dari komponen sistem linux rsync dan crond Job. Rsync digunakan untuk proses pengiriman data dari database server ke backup server dan crond job digunakan untuk melakukan penjadwalan terhadap proses backup. Proses backup menggunakan komponen linux ini memiliki kemungkinan kegagalan backup yang minim karena rsync akan mengulangi setiap proses backup yang gagal atau kerusakan data hasil pengiriman.
Ekstraksi Citra Digital Tulisan Mandarin Ke Dalam Terjemahan Tulisan Latin Bahasa Indonesia Dengan Stroke Extraction Dan Template Matching
Authors: Robert Robert , Ananda Ananda , Surya Ibnu
Published: May 2019

Bahasa adalah sistem simbolik dari suara acak, yang digunakan oleh orang untuk berkomunikasi. Mandarin berada di peringkat pertama bahasa yang paling banyak digunakan menurut survei Nationalencyklopedin, dan Mandarin menggunakan huruf yang disebut Hanzi. Manusia memiliki berbagai cara berkomunikasi, salah satunya dengan menulis. Perangkat lunak ini dapat mengenali tulisan melalui gambar dengan menerapkan Pemrosesan Gambar Digital. Penelitian ini bertujuan untuk membangun aplikasi yang dapat mendeteksi Hanzi Mandarin dengan menerapkan Digital Image Processing. Digital Image Processing mengacu pada pemrosesan gambar dua dimensi menggunakan komputer. Metode pemrosesan gambar dengan Stroke Extraction dan Template Mathcing diterapkan solusi untuk masalah ini. Stroke Extraction digunakan untuk melakukan ekstraksi stroke dasar (pi hua) pada gambar Mandarin Hanzi dan kemudian mengenalinya menggunakan Template Mathcing. Aplikasi diuji dengan Receiver Operating Characteristic sehingga kurva yang dapat membantu proses analisis dapat ditarik. Berdasarkan hasil kurva ROC yang dijelaskan, metode Stroke Extraction masih membutuhkan pengembangan karena tingkat keberhasilan yang rendah dalam menghitung sejumlah stroke. Aplikasi yang dibangun berhasil mengekstraksi Mandarin Hanzi baik tulisan tangan dan dicetak dan diterjemahkan ke dalam bahasa Indonesia dengan akurasi 76,47%. Dapat disimpulkan bahwa metode Stroke Extraction dan Template Matching cukup efisien dalam mengolah gambar digital Mandarin Hanzi untuk diterjemahkan ke dalam bahasa Indonesia.
Penerapan Hiperheuristik Berbasis Metode Simulated Annealing untuk Penyelesaian Permasalahan Optimasi Lintas Domain
Authors: Angresti Nisa Dwi , Djunaidy Arif , Mukhlason Ahmad
Published: May 2019

Permasalahan optimasi lintas domain merupakan permasalahan optimasi yang sangat rumit karena masing-masing permasalahan mempunyai karakteristik yang berbeda. Penyelesaian terhadap permasalahan optimasi lintas domain tersebut melibatkan metode pencarian komputasional untuk memperoleh hasil yang mendekati optimal. Beberapa peneliti terdahulu mengembangkan metode hiperheutistik untuk memperoleh solusi generik yang diharapkan mampu memberikan hasil yang mendekati optimal. Hasil penelitian terdahulu mengidikasikan bahwa strategi hiperheuristik yang lebih baik diperlukan guna memperoleh solusi yang mendekati optimal untuk lintas domain permasalahan. Dalam penelitian ini, upaya untuk mendapatkan solusi generik yang mendekati optimal terhadap permasalahan optimasi lintas domain dilakukan dengan mengembangkan strategi pencarian komputasional pada tatanan High Level Heuristics (HLH) dalam mengatur proses seleksi pada rangkaian  Low Level Heuristics (LLH) kemudian melakukan mekanisme penerimaan solusi. Penelitian ini menguji metode Simulated Annealing (SA) sebagai mekanisme penerimaan solusi dalam tatanan HLH agar dapat menghasilkan solusi mendekati optimal pada berbagai domain masalah optimasi yang dikombinasikan dengan metode seleksi LLH. Penelitian ini melakukan eksperimen untuk menentukan nilai parameter yang tepat untuk mengotomatiskan parameter kontrol SA dalam menyelesaikan permasalahan optimasi lintas domain. Strategi yang digunakan dalam penelitian ini diuji coba untuk menyelesaikan enam permasalahan optimasi domain yang berbeda yang diperoleh dari HyFlex, yaitu Satisfiability (SAT), Bin Packing, Flow Shop, Personnel Scheduling, Travelling Salesmen Problem (TSP), dan Vehicle Routing Problem (VRP). Dari hasil pengujian terhadap enam permasalahan optimasi tersebut, nilai parameter untuk suhu awal T adalah 100 dan faktor penurunan suhu α adalah 0,995.
Ekstraksi Basis Pengetahuan Ke Dalam Basisdata Graf Menggunakan Graf Property
Authors: Wahyudi Wahyudi , Akbar Fajril
Published: May 2019

Salah satu jenis commonsense knowledge adalah basis pengetahuan, yaitu kumpulan fakta dan informasi umum yang diketahui manusia. Basis pengetahuan yang tersedia sangat banyak, kami memilih Yago karena Yago menggabungkan beberapa sumber data menjadi sebuah ontologi. Fakta fakta ini saling terhubung sehingga representasi data graf adalah representasi data yang paling tepat untuk ini. Kita perlu melakukan ekstraksi basis pengetahuan kedalam basisdata graf supaya bisa digunakan untuk berbagai macam aplikasi lainnya. Tools basisdata graf Neo4j dipilih karena bisa melakukan penyimpanan dan pemrosesan graf dan bersifat opensource. Algoritma GPE digunakan untuk melakukan ekstraksi basis pengetahuan kedalam basisdata graf. Penelitian yang kami lakukan menghasilkan sebuah basisdata graf dengan jumlah node : 6.519.734 dan edge yang dihasilkan 18.724.395. Pengujian menggunakan query dengan berbagai permasalahan graf berhasil dilakukan dan memberikan hasil yang diharapkan
The South African Government Vehicle Fleet must be Local
Authors: Rossouw Jannie , Weyer Lourens
Published: May 2019

South Africa is fast approaching a â€œfiscal cliffâ€ owing to rising government expenditure on civil service remuneration, social security grants and interest payments on government debt. The fiscal cliff is defined as the point where civil service remuneration, social security grants and interest payments on government debt account for 100 per cent of government tax revenue. Currently these three items account for some 70 per cent of the governmentâ€™s tax revenue. The South African government has already increased the value-added tax (VAT) rate from 14 per cent to 15 per cent, but a reduction in government expenditure must also be considered to avert the fiscal cliff. Unnecessary government expenditure must, therefore, be identified and eradicated. One example where savings can be recorded is expenditure on imported vehicles purchased for the government vehicle fleet at central and provincial government level. These vehicles can easily be substituted by the purchase of locally-produced vehicles. Research in this paper shows that a policy of exclusive purchases of locally-produced vehicles for the government fleet at central and provincial government level would (based on 2017-figures) lead to fiscal relief, higher employment in the automotive manufacturing sector and a once-off positive economic growth impact for the South African economy. This matter has also found some support amongst members of Parliament.
The Correlation and Separation of Academic Theology and the Local Church
Authors: Pillay Jerry , Womack Jonathan
Published: May 2019

This article provides an overview of the historical correlation between the church and academic theology as well as a brief account of its demise. In assessing the correlation it is demonstrated how, for the first 1Â 500 years of Christian history, a correlation between academic learning and the church was the norm. A brief outline of the demise of this tradition is shown to allow the reader to comprehend how the correlation faded. At a time when the future of academic theology is under great discussion, this article provides a somewhat forgotten history that can add great weight to the current debate on church and the academy.
Bishop Alfred Robert Tucker and the Establishment of the African Anglican Church
Authors: Gathogo Julius M.
Published: May 2019

Book Review
Church and State: A Conflicting Collaboration
Authors: Iheanacho Valentine Ugochukwu
Published: May 2019

St Jerome, both in his wittiness and in his critique of the romance between the church of his time and the Roman Empire in the fifth century, believed that â€œThe church by its connection with Christian princes gained in power and riches, but lost in virtues.â€ The church and the state, whether in the past or in the present, have two particular things in common: peace and order. Both institutions detest disorder and rebellion, but ironically, in their efforts to bring about the desired peace and order, they often disturbed the peace through their quarrels and quibbles. With a keen sense of history, this essay studies the reluctance with which the church in the West and in the East embraced secular authorities in the civil administration of society for the sake of â€œpeaceâ€ and â€œorder.â€
EFFECTS OF PARTIALLY HYDROGENATED PYRIDINES (CYANOTHIOACETAMIDE DERIVATIVES) ON THE BLOOD OF RATS WITH COMBINED PARACETAMOL-ALCOHOLIC LIVER INJURY
Authors: Bibik Elena Yu. , Krivokolysko Bogdan S. , Burdeynaya Anna A. , Demenko Andrey V. , Frolov Konstantin A. , Dotsenko Viktor V. , Krivokolysko Sergey G.
Published: May 2019

Aim. In this research, we studied the parameters of blood biochemical analysis in rats with combined paracetamol-alcoholic liver injury after its pharmacological correction by newly synthesized partially hydrogenated pyridines (cyanothioacetamide derivatives).

Materials and methods. 50 samples of new derivatives of partially hydrogenated pyridines synthesized on the basis of the “Chemex” Research Laboratory of the Vladimir Dal’ Lugansk National University underwent virtual bioscreening, which allowed the selection of 4 compounds, the biological activity of which may be associated with the effect on the protein synthesis and detoxifi cation function of the liver. The experiment was conducted on 48 white outbred male rats. For 14 days, the rats of the control and experimental groups were intragastrically injected with 1 ml of 40% ethanol and paracetamol at a dose of 500 mg/kg once a day. Pharmacocorrection with a thiotriazoline reference drug (50 mg/kg) and pyridine derivatives at a dose of 5 mg/kg was performed from the fourth day. On the 15th day, blood was sampled to determine the level of total bilirubin, alanine aminotransferase, aspartate aminotransferase and thymol turbidity test.

Results. The value of total bilirubin in the blood of the rats treated with CV046 compounds was 34.88% lower than that in the control group. The animals of the test groups receiving CV047 also showed signifi cant differences with the control group in terms of bilirubin level (a decrease of 31.78%). The AST values in the blood of rats in the test groups had no signifi cant differences as compared with intact animals. Following 10 days of pharmacological correction of combined paracetamol-alcoholic liver injury with CV146, the total bilirubin level in the blood decreased by 26.36% in comparison with the control group, with the activity of ALT and AST demonstrating the levels of intact values.

Conclusions. The conducted screening studies of four partially hydrogenated pyridines — cyanothioacetamide derivatives — using the model of combined paracetamol-alcoholic liver injury when used at a dose of 5 mg/kg during ten days have shown a high hepatoprotective and detoxifying activity of the following three compounds: СV046 (2-[(9-tert-butyl-1,5-dicyano4-oxo-3-azaspiro[5,5]undec-1-en-2-yl)thio]-N-(2-ethylphenyl)acetamide — IUPAC), СV047 (2-[(9-tert-butyl-1,5-dicyano-4-oxo-3-azaspiro[5,5]undec-1-en-2-yl)thio]-N-(4-fl uorophenyl) acetamide) and СV146 (benzyl 4-(4-chlorophenyl)-5-cyano-6-({2-[(3,4-dimethylphenyl)amino]-2-oxoethyl}thio)-2-methyl-1,4-dihydropyridine-3-carboxylate).
THE HEALTH STATUS OF TEENAGERS IN KRASNODAR KRAI
Authors: Burlutskaya Alla V. , Statova Anastasia V. , Gurina Elena S.
Published: May 2019

The aim is to assess the health status (morbidity and disability) of adolescents in Krasnodar Krai.

Materials and methods. We analysed the offi cial statistical data on the health state of 10– 18 year-old children in Krasnodar Krai during the 2013–2017 period using Form 12 “Information on the number of diseases registered in patients living in the service area of the medical organization” and Form 19 “Information on disabled children”. In addition, the data presented in the report “On medical support of citizens before their initial military registration in Krasnodar Krai in 2017” was analysed.

Results. Diseases of the respiratory tract, digestive system, musculoskeletal system and connective tissue, as well as traumas and poisoning, are shown to be leading conditions in the structure of adolescents’ general and primary morbidity. Over the past fi ve years, a decrease in the overall and primary morbidity in 10–14 year-old children has been recorded, although these indicators have shown a growing trend in children aged 15–18 years old. An increase in general and primary disabilities across all age groups in Krasnodar Krai was revealed.

Conclusion. An increase in the primary and overall morbidity in 15–18 year-old adolescents, as well as an increase in primary and general disabilities in 10–18 year-old adolescents has been observed. The problem of adolescent health can be solved using an integrated approach. Positive dynamics can only be achieved by oncerted efforts of medical, public and scientifi c organizations.
INTRODUCTION OF THE 5S LEAN MANUFACTURING METHODOLOGY IN THE HEALTHCARE SYSTEM OF THE RUSSIAN FEDERATION
Authors: Kurmangulov Albert A. , Reshetnikova Yulia S. , Frolova Olga I. , Brynza Natalya S.
Published: May 2019

Aim. In this study, we carry out a problem and critical analysis of the process of implementing the 5S lean manufacturing methodology in the Healthcare System of the Russian Federation.

Materials. 33 Russian and foreign literature sources indexed in the RSCI, Scopus, Web of Science and PubMed databases were reviewed.

Results. This article scrutinizes 5 consecutive steps of the 5S lean manufacturing method for organizing a workplace. This method, which is based on interrelated principles, is being actively introduced into the Russian Healthcare System with the purpose of identifying, reducing and preventing various types of losses.

Conclusion. It is shown that the practical realization of the 5S method is hampered by the specifi cs of medical personnel work and the peculiarities of legislative regulation in RF medical organizations. The application of the 5S methodology, taking into account the existing regulatory framework in the fi eld of healthcare, can increase the manageability of workplaces and create conditions for the effective work of medical personnel.
GUILLAIN — BARRÉ SYNDROME AS A RELEVANT ISSUE OF NEUROLOGY (A LITERATURE REVIEW)
Authors: Velichko Ivan A. , Barabanova Marina A.
Published: May 2019

Acute infl ammatory polyneuropathy is an important research problem of modern neurology. Guillain — Barré syndrome is a severe form of acute polyneuropathy, which is based on autoimmune infl ammation of the myelin sheath of roots and peripheral nerves. Guillain — Barré syndrome is an example of one of the most severe diseases of the nervous system, in which timely diagnosis, proper therapy and qualifi ed care facilitate the achievement of the full recovery of lost functions in most patients. Following an extensive review of Russian and foreign literature, this article discusses modern concepts of Guillain — Barré syndrome, in particular questions related to its epidemiology, etiopathogenesis, classifi cation, clinical features, diagnosis, treatment and prognosis.
CONTROVERSIAL ISSUES OF RADIOLOGIC DIAGNOSIS OF ADENOMYOSIS IN REPRODUCTIVE LOSSES
Authors: Pomortsev Alexey V. , Grushevskaya Yulia V. , Makukhina Tatyana B.
Published: May 2019

Aim. The aim is to analyze the data thus far published on the radiologic diagnosis of adenomyosis in patients with reproductive problems in order to determine promising areas for further scientifi c research.

Materials and methods. An information search for subsequent analysis was performed using E-Library, PubMed and CochraneLibrary electronic bibliographic databases with the following keywords: “ultrasound diagnosis of adenomyosis”, “MRI adenomyosis”, “junctional zone adenomyosis”, “ultrasound adenomyosis”, “diagnosis adenomyosis”, “magnetic resonance imaging adenomyosis”, “adenomyosis junction”.

Results. Imaging techniques are prioritized in diagnosing the initial incidence of adenomyosis. The value of such techniques increases when analyzing the causes of implantation failures. Key issues associated with the modern radiologic diagnosis and monitoring of adenomyosis during treatment have been considered on the basis of the standardization of studies, classifi cation of the disease, assessment of the diagnostic accuracy and prognostic value of imaging techniques in patients with reproductive losses and infertility.

Conclusion. Promising areas of scientifi c research are found to be the specifi cation of optimal diagnostic timeframes, informativity of diagnostic criteria for 3D reconstruction, MRI, elastography, angiography, as well as the development of prediction methods for healthy childbearing and monitoring the treatment effectiveness.
EVALUATION OF THE CARIES RESISTANCE OF TOOTH ENAMEL ACCORDING TO A STUDY ON THE CHEMICAL COMPOSITION AND MICROSTRUCTURE OF THE TOOTH SURFACE DURING ITS PHYSIOLOGICAL MATURATION
Authors: Domenyuk Dmitry  A. , Chukov Sergey Z. , Arutyunova Anna G. , Ivanuta Oleg O. , Yesaulenko Elena E. , Dmitrienko Sergey V.
Published: May 2019

Aim. In this research, we aimed to investigate the caries resistance of permanent teeth in children at different dentition periods on the basis of data obtained on the chemical composition and microstructure of the tooth surface at the stage of tertiary mineralization.

Materials and methods. We examined 34 premolars without signs of carious lesions, which had been extracted from 11–16 old children following indications for orthodontic treatment, using a high-resolution scanning electron microscope JSM-6610LV (JEOL) equipped with a micro X-ray spectrometer INCA Energy 350XT (Oxford Instruments Analytica, UK). The teeth under study were divided into three groups. The 1st, 2nd and 3rd groups comprised teeth extracted from 11–12, 13–14 and 15–16 year-old children, respectively. In these groups, tooth mineralization continues 6–12, 13–36 and 37–60 months after eruption, respectively.

Results. The X-ray microanalysis of the teeth under study in terms of chemical composition (percentage by mass) showed that the surface enamel accumulates increased concentrations of Ca, P, F and demonstrates a higher Ca/P ratio under reduced levels of C, Na, O during mineralization. It is found that, during early stages of physiological maturation, tooth enamel shows morphological signs of hypo-mineralization, as well as a low caries- and acid resistance, due to its insuffi ciently formed prismatic structure, lack of a protective layer, signifi cant permeability and a large number of retention points.

Conclusion. The obtained results demonstrate the possibility of applying high-resolution electron microscopy and X-ray microanalysis for the study of dental hard tissues in dental practice. The development and implementation of personalized approaches to the prevention of caries, which are based on the selective use of remineralizing preparations and vitaminmineral supplements, can increase the caries- and acid resistance of tooth enamel at all stages of its physiological maturation.
TREATMENT OUTCOMES OF THE ALVEOLAR RIDGE REGRESSIVE TRANSFORMATION USING AUTOLOGOUS ADIPOSE-TISSUE DERIVED STROMAL VASCULAR FRACTION
Authors: Perova Marina D. , Karpyuk Vladimir B. , Sevostyanov Igor A. , Gilevich Irina V.
Published: May 2019

Aim. The study was performed in order to assess the size, structure and chewing ability of the maxillary ridge reconstructed using autologous adipose-tissue derived stromal vascular fraction (ATD SVF) in a long-term study (10 years).

Materials and methods. The study involved 141 patients (61 men, 80 women) aged from 45 to 78 years (mean age 57 years) with a regression transformation of the alveolar ridge of the upper and lower jaw. In the test group (TG), 112 osteoplastic surgeries were performed using autologous adipose-tissue derived stromal vascular fraction (ATD SVF) followed by the installation of 297 dental implants into the reconstructed ridge to restore the chewing function. The control group (CG) comprised 117 surgeries performed according to generally accepted methods followed by the installation of 323 artifi cial supports. The size of the alveolar ridge and the support function of the reconstructed bone were evaluated during the period of up to 10 years. In the histological and histomorphometric study, 27 trephine biopsy specimens of reconstructed bone obtained during dental implantation were studied. The resulting digital material was processed by conventional methods of variation statistics.

Results. The results of a comparative study have confi rmed the advantages of the proposed approach with the use of ATD SVF over current generally accepted methods for the reconstruction of the jaw alveolar ridge. The use of ATD SVF in the composition of osteoplastic material allows the required degree of augmentation of the atrophied bone area to be achieved with a minimal risk of complications and reoperations (8% and 21% of cases in TG and CG, respectively, p = 0.231), along with the optimal morphological characteristics of the regenerate (40.14 ± 3.36 and 24.23 ± 2.63 percent of viable mineralized bone tissue on sections of trephine biopsy specimens from TG and KG, p = 0.001). These results ensure reliable osseointegration of artifi cial supports in the reconstructed alveolar ridge and a high effi ciency of orthopedic treatment with implant supports during the period of up to 10 years (97% and 88% in TG and CG, respectively, r˂0.001).

Conclusion. The proposed innovative approach can be recommended as a basis for a surgical protocol with a pronounced regression transformation of the jaw alveolar ridge. This will allow the chewing function to be restored more successfully and predictably with the use of artifi cial supports in the reconstructed bone in this category of patients.
Equoterapia como proposta de intervenção para pacientes com Paralisia Cerebral: revisão integrativa
Authors: Castro Fernando Ribeiro , Magalhães Marcio Marinho
Published: May 2019

Objetivo: Investigar na literatura cientifica os efeitos da equoterapia em pacientes com paralisia cerebral. Métodos: Trata-se de uma revisão integrativa, de estudos disponíveis nas bases de dados Scielo e Biblioteca Virtual em Saúde, publicados entre os anos de 2010 a 2017 nos idiomas português e inglês, no qual totalizaram 9 estudos. Resultados: Pode-se verificar em várias pesquisas que a equoterapia foi capaz de melhorar a capacidade funcional, a função motora grossa, a autoestima, capacidade de autocuidado, comunicação e cognição social. O cavalo é capaz de gerar e transmitir ao paciente vários movimentos de maneira sequenciada e simultânea, nesse sentido a equoterapia em pacientes com paralisia cerebral é capaz de proporcionar o controle postural, através do estímulo das reações normais e por meio de estímulos repetitivos de coordenação da postura. Conclusão: Portanto pode-se verificar que a equoterapia possui benefícios no tratamento de alterações funcionais e até mesmo de caráter social e emocionais em pacientes com paralisia cerebral.
Buz Tırmanışı Yapan Dağcıların Yaşam Kalitesinin İncelenmesi
Authors: GÜRER Burak
Published: May 2019

Buz tırmanışı risklerin olduğu, kazaların ve ölümlerin
yaşandığı riskli bir spordur. Bu yüzden bu sporu yapanların yaşam tarzları,
kişilik özellikleri, karar verme becerileri gibi özellikleri merak edilmektedir.
Bu araştırmanın amacı, buz tırmanışı yapan sporcuların yaşam kalitesine etki
eden nedenleri incelemektir. Araştırma verileri 22-26 Ocak 2016 tarihlerinde
Erzurum’da yapılan 2. Uluslararası Emrah Özbay buz tırmanışı festivalinde
araştırmacı tarafından toplanmıştır. Araştırmada amaçsal örneklem tekniği
kullanılmıştır. Araştırmaya 93 (77 erkek, 16 kadın) sporcu katılmıştır.
Araştırmada Dünya Sağlık Örgütü tarafından geliştirilmiş olan WHOQOL-BREF
(Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısaltılmış Versiyonu)
kullanılmıştır. Ölçeğin Türkçe geçerlilik ve güvenilirliği Eser vd., (1999)
tarafından yapılmıştır. Cronbach Alpha iç tutarlılık katsayısı .87 olarak
bulunmuştur. Toplanan veriler istatistiksel paket program (SPSS 22.0)
aracılığıyla analiz edilip sonuçlar yorumlanmıştır. Araştırma verilerinin
değerlendirilmesinde t-testi ve One Way Anova analizi kullanılmıştır. Tırmanış
deneyimi ve eğitim durumuna göre istatistiksel olarak anlamlı farklara
ulaşılmıştır. Yaş, cinsiyet, meslek ve medeni durum değişkenine göre
istatistiksel olarak anlamlı farklar bulunamamıştır. Buz tırmanış deneyimi
fazla olanların genel yaşam kalitelerinin ve sağlıklarının daha iyi olduğu
sonucuna ulaşılmıştır. Her ne kadar buz tırmanışı yeni bir branş olsa da
deneyim yaşam kalitesini ve sağlığı etkilemektedir. Yine deneyimi fazla olan
sporcuların psikolojik alan değerlerinin daha yüksek olduğu görülmüştür. Yani
tırmanış sırasında ve ortamında olumlu duyguların, düşünme, öğrenme ve
dikkatini toplamanın bu alan puanını yükselttiğini düşünülmüştür. Eğitim
düzeyinde, çevresel alanda lisansüstü eğitime sahip olanlar lehine sonuçlar
bulunmuştur. Yani maddi kaynaklar, fiziksel güvenlik ve emniyet, ev ortamı,
yeni bilgi ve beceri edinme fırsatları lisansüstü eğitime sahip olanlar için daha
önemlidir. Sonuçta deneyimli olmak ve eğitim durumunun buz tırmanışı yapan
dağcıların yaşam kalitesine etki ettiği ortaya konmuştur. Genel olarak buz
tırmanışı yapanların yaşam kalitesinin iyi olduğu söylenebilir. Buz tırmanışı
yüksek efor istemekte ve buna bağlı olarak ta yaşam kalitesinin iyi olması
gerekmektedir.
Energy Threshold for Chiral Symmetry Breaking in Molecular Self-Replication
Authors: Hawbaker Neil , Blackmond Donna
Published: May 2019

We have determined the energy required for symmetry breaking and chiral amplification in the Soai autocatalytic reaction. This work examines the likelihood that parity violation energy difference of enantiomers is implicated in the origin of chiral symmetry breaking and highlights the challenges inherent in a search for a prebiotically plausible version of Soai autocatalysis.
Wall- and Hybridisation-Selective Synthesis of Nitrogen-Doped Double-Walled Carbon Nanotubes
Authors: Carini Marco , Shi Lei , Chamberlain Thomas , Liu Meng , Valenti Giovanni , Melle-Franco Manuel , Paolucci Francesco , Khlobystov Andrei , Pichler Thomas , Mateo-Alonso Aurelio
Published: May 2019

Controlled nitrogen-doping is a powerful methodology to modify the properties of carbon nanostructures and produce functional materials for electrocatalysis, energy conversion and storage, and sensing, among others. Herein, we report a wall- and hybridisation-selective synthetic methodology to produce double-walled carbon nanotubes with an inner tube doped exclusively with graphitic sp2-nitrogen atoms. Our measurements shed light on the fundamental properties of nitrogen-doped nanocarbons opening the door for developing their potential applications.
In the Quest for a Stable Triplet State in Small Polyaromatic Hydrocarbons : An In-Silico Tool for Rational Design and Prediction
Authors: Rano Madhumita , Ghosh Sumanta K , Ghosh Debashree
Published: May 2019

Combining the roles of spin frustration and geometry of odd and even numbered rings in polyaromatic hydrocarbons (PAHs), we design small molecules that show exceedingly small singlet-triplet gaps and stable triplet ground states. Furthermore, a computationally efficient protocol with a model spin Hamiltonian is shown to be capable of qualitative agreement with respect to high level multireference calculations and therefore, can be used for fast molecular discovery and screening.
Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration
Authors: Rosales Mariana Aparecida Brunini , Shu Daisy Y , Iacovelli Jared , Saint-Geniez Magali
Published: May 2019

The retinal pigment epithelium (RPE) supports visual processing and photoreceptor homeostasis via energetically demanding cellular functions. Here, we describe the consequences of repressing peroxisome proliferator-activated receptor γ coactivator-1 α (PGC-1α), a master regulator of mitochondrial function and biogenesis, on RPE epithelial integrity. The sustained silencing of PGC-1α in differentiating human RPE cells affected mitochondria/autophagy function, redox state, and impaired energy sensor activity ultimately inducing epithelial to mesenchymal transition (EMT). Adult conditional knockout of PGC-1 coactivators in mice resulted in rapid RPE dysfunction and transdifferentiation associated with severe photoreceptor degeneration. RPE anomalies were characteristic of autophagic defect and mesenchymal transition comparable with the ones observed in age-related macular degeneration. These findings demonstrate that PGC-1α is required to maintain the functional and phenotypic status of RPE by supporting the cells’ oxidative metabolism and autophagy-mediated repression of EMT.