bluuebunny/crossref_metadata_2025 huggingface dataset:
A geometrical feature-based framework for pedestrian crossing recognition
Authors: Khaliluzzaman Md
Published: July 2024

In this work, a framework for the recognition of pedestrian crossing (PC) regions based on geometrical features is proposed. A distinctive feature of a pedestrian crossing (PC) is that each end point of the horizontal strip edges at pedestrian crossings intersects with a vertical stripe width edge, which comprises two connected points (2CP). Another unique feature of PC is that the PC stripe's edges are formed in ascending parallel order. These two features are utilized to identify the PC candidate region in the PC image. Where the 2CP and parallel edge segment in sorted order is used to validate and justify the PC region. Finally, classifier support vector machine (SVM) confirms the potential PC region. Here, the features of the candidate area are extracted using the uniform rotationally invariant Local Binary Pattern (LBP). The proposed framework is tested with our own dataset, and the results reveal significant improvement over previous work.
IIUC Studies, Vol.-20, Issue-1, June 2023, pp. 59-86
Dialysis disequilibrium syndrome
Authors: Ansary Eusha Ahmad Fidalillah , Chowdhury Jubaida Khanam , Azim Muhammed Arshad Ul
Published: July 2024

A clinical constellation of neurologic symptoms and signs that can arise during or soon after dialysis, particularly during the initial stages of the procedure, is known as the dialysis disequilibrium syndrome (DDS). This is an exclusion diagnosis that affects people who are hyperosmolar and uremic; quick correction with renal replacement therapy causes cerebral edema and elevated intracranial pressure, which in turn causes clinical neurologic symptoms. Although DDS is most frequently linked to hemodialysis, it can also happen to individuals who need continuous renal replacement therapy (CRRT) due to acute kidney injury. It hasn't been mentioned in relation to peritoneal dialysis as of now. There is a wide range of signs and symptoms, from headaches and restlessness to coma and death. The specific mechanisms underlying the development of cerebral edema and increased intracranial pressure, which are the principal contributing factors to this illness and the focus of therapy, are still unknown. Once this illness has manifested, treatment is rarely effective. Therefore, taking action to stop it from developing is essential. This review will look at the pathophysiology of this syndrome and address the things to think about to prevent its development.
J Bangladesh Coll Phys Surg 2024; 42: 282-288
Adhesive Capsulitis Among Diabetic Patients Attending in a Tertiary Care Hospital in Dhaka, Bangladesh
Authors: Khan Md Shah Zaman , Hasan Mohammad Rabiul , Ahmed Sabbir Jashim , Begum Tanjima
Published: July 2024

Background: Adhesive capsulitis also termed as frozen shoulder is a condition characterized by painful and limited active and passive range of motions of the shoulder. It can adversely affect activities of daily living and consequently impair quality of life. The aim of the study was to estimate the prevalence of adhesive capsulitis among diabetic individuals and to study its relationship with age, gender, involved shoulder, body mass index (BMI) and glycaemic control.
Method: A cross-sectional observational study was done in 290 patients attending outpatient department of BIRDEM hospital during the period from1st April 2023 to 30th September 2023. Convenient type of sampling technique was applied. Patients with shoulder pain and restricted active and passive shoulder joint movements were diagnosed as having adhesive capsulitis. Data were statistically analyzed.
Results: Adhesive capsulitis was present in 54 (18.62%) of patients with diabetes. It was found that adhesive capsulitis was higher in increasing age, predominant in female 34(63.0%), more involve in left shoulder 27(50%). Statistically significant association was found with poor glycaemic status.
Conclusion: Adhesive capsulitis is a common problem in diabetic patients. Its occurrence was found to be prevalent with poorly controlled glycaemic status.
J Bangladesh Coll Phys Surg 2024; 42: 230-234
Biocontrol Efficacy Of Native Trichoderma Strains Isolated From Farm And Forest Soil Against Collar Rot (Sclerotium Rolfsii) Of Lentil
Authors: Adhikari P , Shrestha SM , Manandhar HK , Marahatta S
Published: July 2024

Lentil, Lens culinaris is an important pulse crop of Nepal which is susceptible to collar rot disease caused by Sclerotium rolfsii during its early growth stages. The fungus attacks the collar region of the plant, causing rotting of the stem resulting in stunted growth, wilting and reduced productivity. Additionally, it weakens the plant, making them more susceptible to other diseases and stresses such as drought. The pathogen can survive in the soil for extended periods by producing sclerotia. Trichoderma species are known for their antagonistic ability against diverse plant pathogens, including S. rolfsii. This study was conducted to identify promising native Trichoderma isolates for controlling collar rot of lentil during 2020 and 2021 in Chitwan, Nepal. A total of 104 Trichoderma isolates collected from farm and sal, Shorea robusta forest soil and examined in vitro by dual culture technique against S. rolfsii in a completely randomized design. Of them, 30 isolates were selected to study biocontrol potential under a screen house by inoculating both the pathogen and Trichoderma onto lentil seedlings. Subsequently, four promising Trichoderma isolates were selected representing different agro-ecological regions for the field trial in a randomized complete block design to assess their ability to control S. rolfsii in field conditions. Results showed that Trichoderma isolates T73, Forest soil (96.96%); T74, Forest soil (94.49%) and T62, Darchula (88.92%) had shown strong inhibition of S. rolfsii growth, with forest soil isolates exhibiting higher antagonistic potential. In the screen house assay, all Trichoderma isolates increased seed germination, enhanced plant growth, and reduced disease incidence as compared to the control. Trichoderma isolates T49, Bhaktapur, and T31, Banke showed the highest percentage of disease control and percentage yield increase in the field conditions. These findings highlight the consistent potential of Trichoderma for biocontrol of collar rot diseases in lentil.
SAARC J. Agric., 22(1):169-179  (2024)
In Vivo Study On Preventive Effects Of Polyalthia Longifolia Bioformulations Against Black Scurf Disease Of Potato
Authors: Meena P , Gehlot P , Jain JYT , Sharma K
Published: July 2024

Bioformulation prepared by combining Polyalthia longifolia leaf extract with elicitors (neem oil cake) and binders (cow dung) were tested for management of black scurf disease of potato caused by Rhizoctonia solani. Two different application methods- seed dipping and soil amendment were used for in vivo study. The preventive action was studied as a function of decrease in disease severity by PDI (Percent Disease Index) and PEDC (Percent Efficiency of Disease Control) methods. Change in growth characteristics of host plant such as number of leaves/plant, plant height, number of branches/plant, number of flower/plant, number of fruit/plant and weight of fruits were recorded in control and treated plants. Six treatments T1 (formulation no.12 ), T2 (formulation no.7 ), T3 (formulation no.26 ), T4 (formulation no.17) were applied in different combinations and four different control were also maintained. Potato plants were examined for symptoms infected tuber (sclerotia) were quantitatively assessed after 90 DAS (days after sowing). Results of present study indicates that treatment with bioformulation especially T4 treatment not only reduces the infection but also leads to increased growth, health and vigour of the host plant as compared to untreated and synthetic fungicide control. Results were subjected to statistical analysis of student t test, one way ANOVA and post-Hoc comparisons analysis. Significance was measured at p<0.001 and showed highly significant. Statistical analysis at 1% and 5% cadence levels revealed all the treatment are significant clearly indicating that treatment with bioformulations appreciably reduces the disease index as compare to control with significant improvement of growth of host plant. The T4 treatment showed significant inhibitory activity against Rhizoctonia solani and can help to minimize the economic loss of potato crop.
SAARC J. Agric., 22(1): 111-124 (2024)
Optimizing Growing Condition And Planting Date For Growth, Yield And Quality Of Squash In Bangladesh
Authors: Hossen MA , Islam MN , Rahman MJ , Uddin MM , Hossain HMMT , Akther S
Published: July 2024

An experiment was conducted at the Vegetable Research field of Horticulture Research Centre Division, Bangladesh Agricultural Research Institute, Gazipur, Bangladesh, during October 2018 to March 2019 to find out the effect of growing condition and planting date on yield and yield attributes of squash. The experiment comprised two sets of treatments viz., (a) Growing conditions: (i) Open cultivation (C1); (ii) Net protected cultivation (C2) and Cultivation with barrier crop (C3) and (b) Planting dates: (i) 1 November (D1); (ii) 15 November(D2); (iii) 1 December (D3) and (iv) 15 December (D4) in a randomized complete block design (RCBD) with three replications. The variety BARI squash-1 was used in this experiment. The results showed that net protected cultivation showed significantly the highest fruit plant-1, fruit length, yield plant-1 and yield ha-1. Growing condition did not affect quality parameters of quash. Early planting (1 November) showed significantly higher yield, yield attributes and quality parameters than late planting. Fruit diameter did not showed any significant difference irrespective of planting date. The interaction between growing condition and planting dates was significant for yield and quality parameters. Based on the study results it is concluded that maximum yield (49.33 t ha-1) and quality of BARI squash-1 could be achieved through cultivation under net protected condition with 1 November planting.
SAARC J. Agric., 22(1): 97-109 (2024)
IMPLEMENTASI KOMBINASI METODE SAW DAN TOPSIS PEMBERIAN REWARD UNTUK KARYAWAN HOTEL SINGAPORE LAND
Authors: Veronika Devina , Yusda Riki Andri , Rohminatin Rohminatin
Published: July 2024

Penelitian ini bertujuan untuk mengimplementasikan kombinasi metode Simple Additive Weighting (SAW) dan Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) dalam pemberian reward kepada karyawan Hotel Singapore Land. Dalam industri perhotelan yang kompetitif, pemilihan karyawan yang tepat sangat penting untuk meningkatkan kualitas layanan. Metode tradisional seperti wawancara dan tes tertulis seringkali tidak efektif dan memakan waktu. Dibutuhkan sistem pendukung keputusan yang dapat membantu proses pemilihan karyawan secara objektif dan efisien. Penelitian ini mencoba mengatasi masalah tersebut dengan mengkombinasikan metode SAW untuk penilaian terhadap kriteria-kriteria tertentu seperti presensi, masa kerja, kedisiplinan, tanggung jawab, dan kerjasama, serta metode TOPSIS untuk menentukan alternatif terbaik berdasarkan solusi ideal positif dan negatif. Diharapkan hasil penelitian ini dapat membantu manajemen Hotel Singapore Land dalam memberikan reward kepada karyawan yang layak secara cepat, akurat, sistematis, dan transparan, sehingga dapat meningkatkan kinerja dan semangat karyawan serta memberikan pelayanan terbaik kepada tamu-tamu hotel
OPTIMALISASI PENILAIAN AFDELING UNGGULAN PADA PT. PADASA ENAM UTAMA DALAM SISTEM PENDUKUNG KEPUTUSAN BERBASIS VIKOR
Authors: Ningrum Mawar Puspitha , Nurwati Nurwati , Kifti Wan Mariatul
Published: July 2024

PT. Padasa Enam Utama adalah perusahaan perkebunan kelapa sawit yang memiliki program evaluasi afdeling disetiap tahunnya dengan cara memberikan penilaian kepada setiap afdeling. Afdeling adalah satuan yang menjadi ujung tombak dalam pengelolaan perusahaan perkebunan kelapa sawit, sehingga peran pimpinan dan seluruh karyawan afdeling tersebut sangat diperlukan. Proses penilaian afdeling unggulan pada PT. Padasa Enam Utama saat ini masih terbatas pada penggunaan aplikasi Microsoft Excel tanpa sistem aplikasi khusus. Hal ini menyebabkan proses penilaian kurang efektif, tidak transparan, dan memakan waktu yang cukup lama dalam proses penilaian afdeling unggulan. Penelitian ini bertujuan untuk mengembangkan sistem pendukung keputusan berbasis metode VIKOR untuk penilaian afdeling unggulan. Metode kuantitatif digunakan sebagai metode pengumpulan data melalui observasi langsung dan wawancara dengan narasumber langsung. Penelitian ini menunjukkan bahwa penerapan metode VIKOR memberikan hasil penilaian terbaik dengan proses perhitungan yang lebih efisien. Dengan adanya sistem pendukung keputusan ini dapat meningkatkan kinerja perusahaan dalam penilaian afdeling unggulan, serta membuat proses pengambilan keputusan menjadi lebih cepat, efektif, dan efisien.
ANALISIS SENTIMEN ULASAN PENGGUNA PADA GAME ROBLOX DENGAN METODE SUPPORT VECTOR MACHINE DAN NAIVE BAYES
Authors: Alkindi Aditia Fikri , Nasution Nurliana
Published: July 2024

Tujuan penelitian ini adalah untuk mengetahui cara menganalisis sentimen dari ulasan pengguna pada game Roblox dan untuk mengetahui hasil perbandingan performa klasifikasi dengan menggunakan metode Support Vector Machine Dan Naive Bayes dalam menganalisis sentimen ulasan pengguna pada game Roblox. Data yang digunakan pada penelitian ini berjumlah sebanyak 10000 record data ulasan yang di ambil pada tanggal 15 Juni 2024. Hasil yang di peroleh dalam menganalisis sentimen data ulasan pada aplikasi Roblox cenderung mendapatkan sentimen positif dengan persentase 65,06% sedangkan untuk sentimen negatif dengan persentase 34,94%. Support Vector Machine merupakan algoritma terbaik dalam menganalisis sentimen data ulasan pada aplikasi Roblox dengan tingkat akurasi yang paling tinggi pada perbandingan data 90:10 yaitu 90 %, untuk precision, recall, dan f1-score yang dihasilkan pada sentimen positif yaitu 88%, 85%, dan 86%, sedangkan pada sentimen negatif adalah 91%, 93%, dan 92%. Algoritma Naïve Bayes mendapatkan tingkat akurasi yang paling tinggi pada perbandingan data 90:10 yaitu 72,4%, untuk precision, recall, dan f1-score yang dihasilkan pada sentimen positif yaitu 88%, 34%, dan 49%, sedangkan pada sentimen negatif adalah 70%, 97%, dan 81%.
Usefulness of dalbavancin in early discharge and non-hospitalization. It’s time to throw your heart over the obstacle?
Authors: Crapis Massimo , Venturini Sergio , Callegari Astrid , Del Fabro Giovanni , Bramuzzo Igor , De Santi Laura , Pontoni Elisa , Tonizzo Maurizio , Basso Barbara
Published: July 2024

Introduction: Dalbavancin is a semisynthetic lipoglycopeptide long-acting antibiotic approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs). Its features can be useful in the current healthcare scenario characterized by the shortage of available hospital beds.
Materials, methods and results: We implemented several actions in order to optimize the use of dalbavancin allowing an improvement strategy both from the healthcare system and the patient’s perspective in two hospital settings. In the Emergency Department we hospitalized only patients who met the clinical criteria and not the logistic criteria (i.e., the need for antibiotic therapy infusion). During the years 2017-2023, this strategy was applied in 40 cases, thus avoiding 40 hospitalizations for a total saving of 280 days of hospitalization.
In the Internal Medicine ward and surgery department when there was no longer any need for hospitalization, we discharged the patient as early as possible. During the years 2017-2023, this strategy was applied in 189 cases, saving at least 1,134 days of hospitalization. The outcome of the treated patients was favorable in 228 out of 229 patients (99.5%).
Conclusions: Our experience using dalbavancin in ABSSSI has been very satisfactory overall. The efficacy was close to 100%. Minor adverse events of slight severity occurred rarely. At the same time, this strategy allowed a more efficient allocation of hospital beds. Dalbavancin presents an ideal pharmacodynamic/pharmacokinetic profile for the management of ABSSSI especially in settings where shortage of hospital beds is critical.
Clinical, organizational, and pharmacoeconomic perspectives of dalbavancin vs standard of care in the infectious disease network
Authors: Segala Daniela , Barbieri Marco , Di Nuzzo Mariachiara , Benazzi Melissa , Bonazza Aurora , Gentili Francesca , Scolz Kristian , Marra Anna , Cultrera Rosario
Published: July 2024

Introduction: The therapeutic approach to the patient with acute bacterial skin and skin structure infection (ABSSSI) and complicated infections often involves the early transition from intravenous to oral therapy (early switch) or early discharge. Our study aimed to evaluate sustainable and innovative care models that can be transferred to community healthcare and the economic impact of dalbavancin therapy vs Standard of Care (SoC) therapy for the treatment of ABSSSI and other Gram-positive infections including those by multidrug-resistant organisms. We also described the organization of an infectious disease network that allows optimizing the treatment of ABSSSI and other complex infections with dalbavancin.
Materials and Methods: We retrospectively studied all patients treated with dalbavancin in the University Hospital “S. Anna” of Ferrara, Italy, between November 2016 and December 2022. The clinical information of each patient was collected from the hospital’s SAP database and used to evaluate the impact of dalbavancin in early discharge with reduction of length of stay promoting dehospitalization and in improving adherence to antibiotic therapy
Results: A total of 287 patients (165 males and 122 females) were included in the study of which 62 were treated with dalbavancin. In 13/62 patients dalbavancin was administered in a single dose at the completion of therapy to facilitate early discharge. Assuming a 12-day hospitalization required for the treatment of ABSSSI or to complete the treatment of osteomyelitis or spondilodiscitis, the treatment with dalbavancin results in a cost reduction of more than €3,200 per single patient compared to SoC (dancomycin, linezolid or vancomycin)
Conclusions: Dalbavancin has proven to be a valid therapeutic aid in the organization of a territorial infectious disease network given its prolonged action, which allows the dehospitalization with management of even patients with complex infections in outpatient parenteral antimicrobial therapy.
The Clinical Utility of Botulinum Toxin in the Field of Otolaryngology
Authors: Kang Min Seok , Byeon Hyung Kwon
Published: July 2024

Botulinum toxin, originally identified in relation to botulism, has evolved from being considered a perilous pathogen to an invaluable therapeutic agent. First utilized by Alan Scott in 1977 to treat strabismus under the commercial name, Oculinum, the toxin received Food and Drug Administration approval in 1989 and was subsequently rebranded as Botox. Its clinical applications have expanded notably, especially in the field of otolaryngology, proving effective in managing conditions such as spasmodic dysphonia, essential vocal tremor, and chronic salivary gland disorders. Moreover, botulinum toxin has shown promising results in treating persistent chronic rhinitis, objective tinnitus, and synkinesis following facial palsy, significantly improving involuntary facial movements. This paper details the diverse applications and methodologies of botulinum toxin across various ENT disorders, illustrating its growing scope and significance in medical practice.
Achieving Organizational Metamorphosis Through Developing a Diversity, Equity, and Inclusion Initiative
Authors: Voutsas Kostas , Voutsas Christian
Published: July 2024

Today’s workforce reflects and will continue to reflect diversity. If these changes represent America’s future demographic reality, organizations will undergo a massive metamorphosis. A questionnaire was submitted to 300 business students to assess their attitudes towards diversity. Specifically, it investigates whether there is a difference in attitude and assesses whether business students are open to working with an increasingly diverse workforce. The study’s results support the hypotheses that different ethnic groups value diversity differently, and that the more years living in a diverse country, the more individuals increase their diversity tolerance. Diversity, equity, and inclusion initiatives increase in popularity since they build awareness and skills that help cultivate a safe, compassionate, and equitable organizational culture where everyone feels valued. This article discusses implementing a diversity, equity, and inclusion (DEI) initiative to improve an organization’s culture. The five-step DEI Organizational Metamorphosis Model explores how to strengthen an organization’s quality of life through implementing strategic DEI initiatives.
Metodologias não convencionais para ensinar imunologia aos universitários
Authors: Miranda Maria Eduarda Lacerda , Almeida Martha Elisa Ferreira de
Published: July 2024

Os temas de imunologia são complexos e de grande importância na formação acadêmica de graduandos da área da saúde, sendo que as metodologias não convencionais são ferramentas de elevada relevância para ajudar no aprendizado e na sua fixação. Assim, o objetivo deste estudo é demonstrar a utilização de metodologias ativas no ensino de imunologia para universitários dos Cursos de Nutrição e Ciências Biológicas, Campus Rio Paranaíba, Universidade Federal de Viçosa. Durante o período da pandemia, no ano de 2021, os assuntos da Covid-19 foram trabalhados utilizando uma música e mapas mentais. Os discentes ouviram a música ASAS elaborada pela docente da disciplina e fizeram atividades relacionadas ao tema como responder perguntas, redações e desenhos com a temática da música. Na aula sobre a sinapse imunológica os alunos fizeram desenhos para ilustrar o assunto. No final da disciplina os alunos elaboraram em dupla um mapa mental na plataforma do Canva. Em 2022, com o retorno das atividades presenciais, as temáticas das sinapses imunológicas e dos soros e vacinas foram trabalhadas utilizando a técnica das xilogravuras. A maioria dos alunos realizou as atividades propostas dos desenhos e dos cordéis, sendo relatados por alguns que estes trabalhos geram conhecimentos e fixação do conteúdo, além de trabalhar o lado artístico de temas tão complexos. Conclui-se que as metodologias ativas não convencionais foram eficazes para gerar conhecimentos e sua fixação, além de estimularem a criação artística pelos alunos.
O impacto do uso de telas digitais no desenvolvimento cognitivo infantil: Uma revisão de literatura
Authors: Cavalcanti Bruna Lima Durans , Soares Giovana Balbinot , Lima Jaqueline Rego , Gaspar Christian Diego de França , Oliveira Karyne Gleyce Zemf
Published: July 2024

Introdução: É inegável a grande participação de tecnologias em diversas áreas da vida cotidiana, e continuamente essas tecnologias são apresentadas precocemente às crianças, principalmente na fase inicial do desenvolvimento. Esse período é reconhecido como o de maior maleabilidade cerebral, que permite favorecimento da aprendizagem por meio de estímulos externos e o desenvolvimento de diversas habilidades. Nesse sentido, destaca-se que o uso excessivo e desregrado de telas, é elencado como fator de risco para interferências no aprimoramento neuropsicomotor. Objetivo: Descrever as consequências do uso de telas digitais para o desenvolvimento cognitivo infantil. Metodologia: Trata-se de uma revisão integrativa de literatura dos últimos 10 anos, nas plataformas: Scielo, Lilacs e MEDLINE. Revisão de literatura: O uso desregrado das tecnologias afeta as crianças, e apresenta evidente impacto no desenvolvimento cognitivo na infância, como deficiências intelectuais, déficit de atenção, dificuldades na fala, complicações psicológicas, como a depressão e ansiedade. Além disso, pode estar relacionado ao aumento dos casos de obesidade infantil, deficiências nutricionais, alterações metabólicas e distúrbios do sono. O uso de telas foi positivo para o desenvolvimento infantil quando utilizado para atividades lúdicas e aprendizado ativo. Conclusões: A utilização, em excesso, das telas digitais pode acarretar diversas consequências no desenvolvimento neuropsicomotor, além de prejudicar a saúde física e mental, aumentando a probabilidade de sedentarismo infantil e de não desenvolvimento de habilidades motoras e comunicativas. Logo, pode contribuir para o surgimento de doenças como obesidade e depressão.
Gastroenterite de origem infecciosa presumível uma condição sensível à Atenção Primária em Saúde: Hospitalizações na 1ª Regional de Saúde do Estado do Paraná entre 2013 a 2023
Authors: Millnitz Larissa , Siczkoriz Natalli Tedesco , Bridi Aline Lopes da Silva , Lourenço Alyce Steberl , Reis Denny Rafael Perusso dos , Silva Elsa Gomes da , Gomes Morgana Sousa , Oliveira Elia Machado de , Ferreira Wellington Fernando da Silva , Dutra Denecir de Almeida
Published: July 2024

Objetivo: Descrever parte do perfil epidemiológico de hospitalizações e óbitos por diarreia e gastroenterite de origem infecciosa presumível na 1ª Regional de Saúde (Paranaguá) na macrorregião leste do Estado do Paraná entre os anos de 2013 a 2023, refletindo a importância da atenção primária à saúde. Metodologia: Trata-se de um estudo descritivo epidemiológico retrospectivo, baseado em dados secundários, proveniente do Sistema de Informação Hospitalar (SIH), no DATASUS. Resultados: Foram catalogadas 622 internações hospitalares por ‘’Diarreia e Gastroenterite de Origem Infecciosa Presumível’’, CID: (A09), considerando hospitais públicos e privados, e todas as categorias de atendimento. Destes 12 registros evoluíram a óbito no recorte temporal. A etnia, predominantemente apontada foi a variável de inespecificidade descrita como ‘’sem informação’’ e a variável raça/cor ‘’branca’’. Os gêneros evidenciados nas internações nestes períodos sobressaíram ao sexo masculino, entretanto não sendo significativo aos óbitos. Quanto à faixa etária, ressaltou-se entre 1 a 4 anos, apresentando o maior quantitativo de hospitalizações, seguida da faixa etária de 5 a 9 anos. Contudo houve a divergência para a faixa etária aos casos de óbitos para predominância acima de 40 anos. Na regional de saúde o município de Paranaguá apresentou mais de 50% das hospitalizações. Apresentaram-se ainda, as variáveis referentes à média de permanência das hospitalizações, os valores de serviços hospitalares, valores médios de internações e taxa de mortalidade. Conclusão: Portando, no período levantado, pode-se inferir como um dos principais fatores de risco o saneamento básico inadequado, acesso aos serviços de saúde e educação ambiental.
Phytotherapy applied to Dentistry: A literature review
Authors: Santos Pedro Guimarães Sampaio Trajano dos , Silva Maria Clara Domingues da , Freitas Yasmim Cristina de Souza , Rocha Vitória Souza , Marques Filho Eudoro de Queiroz , Cunha Rodolfo Scavuzzi Carneiro , Silva Luciano Barreto
Published: July 2024

Objective: The objective of this narrative literature review article was to address the origin and history of Phytotherapy, some types of herbal medicines and their benefits within dentistry, addressing how the production of a herbal medicine occurs and what difficulties may exist within Phytotherapy. Methodology: Searches and research were carried out using descriptors, websites, newspapers and other databases, including: Research, society and development journal, Web of Science, DeCs, VHL/BIREME, Science Direct, PUBMED Central, The Cochrane Library, Scielo journals and gray literature. Results: We obtained the result that Phytoterpia has great utility and benefits within dentistry, positive points given its low market value and mainly due to its antibacterial, anti-inflammatory, antihemorrhagic, anesthetic and other functions.
Fisiopatologia e clínica da Nefropatia por IgA: Uma revisão de literatura
Authors: Campos Milena Figueiredo , Martins Luiza Melgaço , Sanches Pedro Luccas Leal Contini , Almeida Eduarda Naves Gonçalves de , Oliveira Caio Antônio Lucena de , Campos Noeme Rocha Pereira , Silva Aline Lopes Zacarias e , Souza Luiz Eduardo Alencar de , Anacleto Arthur Augusto Sa , Costa Gabriel Starling , Araújo Maria Thereza de Oliveira , Oliveira Rafella Uzeloto de
Published: July 2024

Introdução: A nefropatia por imunoglobulina A (IgAN) afeta predominantemente crianças e adultos jovens, com clínica influenciada por fatores como etnia e idade. Atualmente, não existem biomarcadores séricos ou urinários confiáveis para o diagnóstico da IgAN, nem um tratamento específico para a condição. Assim, este estudo visa explorar os aspectos da doença renal para preencher lacunas no conhecimento atual. Metodologia: Trata-se de uma revisão integrativa acerca da IgAN. Utilizou-se dados das bases Biblioteca Virtual de Saúde (BVS), Scientific Eletronic Library of Medicine (SciELO) e National Library of Medicine (PubMed), a partir do cruzamento dos descritores “nefropatia por IgA”, “doença renal”, “biomarcadores”, “biópsia” e “manifestações clínicas” para responder à questão formulada através da estratégia PICO. Resultados e discussão: A epidemiologia da IgAN é pouco conhecida, mas sabe-se que é mais prevalente em homens crianças e adultos jovens. A patogênese envolve a produção de uma IgA anômala após gatilhos, como infecções ou exercícios vigorosos, que serão combatidas por autoanticorpos formando imunocomplexos depositados nos glomérulos renais. Isso resulta em alterações histológicas que levarão a variadas manifestações clínicas, principalmente hematúria visível. O diagnóstico definitivo requer biópsia e o prognóstico depende, principalmente, do grau da proteinúria e da função renal remanescente. O tratamento atual envolve medidas de suporte para controle da pressão arterial e da proteinúria, com a imunossupressão sendo considerada em casos graves. Conclusão: Ainda existem conflitos acerca de patologia e do tratamento da IgAN. Por isso, são necessários mais estudos para esclarecer os melhores manejos clínicos e os fatores de risco para a condição.
O impacto da Dermatite Atópica na saúde mental da população pediátrica: Uma revisão integrativa
Authors: Teixeira Fernando Tavares Brasil , Aguiar Antonia Victória Silva , Nogueira Ana Paula de Souza , Silva Neto Luiz Fernando Leite da , Farias Lucas Miquilini de Arruda , Pires Carla Andréa Avelar
Published: July 2024

Objetivo: Analisar dados na literatura atual sobre dermatite atópica em crianças e adolescentes e suas repercussões psicológicas nesses grupos. Metodologia: Trata-se de uma revisão integrativa da literatura, realizada nas principais bases de dados em saúde, com os seguintes operadores booleanos: “Atopic Dermatitis” AND “Child” OR “Adolescent” AND “Mental Health” OR “Mental Disorder”. Resultados: Foram encontrados, primordialmente, 186 artigos a partir da busca em 3 bases de dados, dos quais foram incluídos, seguindo os critérios de inclusão e exclusão propostos, com filtro para os estudos dos últimos cinco anos, 18 artigos para a composição final do estudo. Conclusão: Demonstrou-se uma íntima relação entre as atopias, principalmente a Dermatite Atópica, e o comprometimento da saúde mental no grupo estudado, sobretudo devido às repercussões na autoestima, no humor, nas relações interpessoais e no desenvolvimento cognitivo e escolar, tendo-se como doenças mais prevalentes os déficits de atenção, a depressão e a ansiedade. Desse modo, torna-se imprescindível o acompanhamento multidisciplinar em toda a população pediátrica desde o diagnóstico dessa condição, para que se evite ou minimize a evolução do quadro psiquiátrico e suas complicações.
Ratio Legis of Article 12 Letter F : The Extortion in Corruption
Authors: Rahmatina Putri Izzati , Ismail Kautsar , Lowell Bautista
Published: July 2024

Corruption crimes encompass a variety of offences, one of which is the Extortion Offence. Extortion offences involve offenders proven to demand, receive, or withhold payments through force or threats on material matters while performing their duties as certain officeholders. In Indonesia, regulations for corrupt acts involving extortion offences are outlined in Article 12 letter f of Law Number 20 of 2001, amending Law Number 31 of 1999 on the Eradication of Criminal Acts of Corruption, as well as Article 425 paragraph (1) of the Indonesian Criminal Code. The extent to which a person is considered to have committed a corrupt act involving extortion is a crucial aspect of corruption offences. This study employs the Normative Research Method utilizing statutory and conceptual approaches, with legal material analysis conducted through descriptive means. The findings show that significance of Article 12 letter f in the Corruption Eradication Act as an extension and lex specialist in Article 425 paragraph (1) of the Criminal Code. Officials can take measures to prevent such misconduct to avoid improper cash handling or extortion by those in positions of authority over them. This study offers an in-depth study of illegal levies in corruption, emphasizing Article 12 letter f of Law Number 20 of 2001, aiming to bridge the gap of previous studies and provide practical insights for law enforcement in anti-corruption efforts in Indonesia through normative legal research.
Tailoring treatment in early-stage breast cancer
Authors:   , de Boo Leonora Wijnandina
Published: July 2024

This thesis focuses on identifying prognostic and predictive biomarkers that may guide treatment decisions for patients with early-stage HER2-negative breast cancer (BC) or triple-negative BC (eTNBC). We studied the value of histopathologic tumor traits, in addition to stromal-compartment tumor infiltrating lymphocyte (sTIL) levels, in the risk stratification of young patients with node-negative eTNBC who did not receive adjuvant systemic treatment. Lymphovascular invasion and fibrotic focus showed independent prognostic value for breast cancer-specific survival.
Furthermore, we described that BCs with the expression of the meiotic DNA break regulator HORMAD1 are associated with homologous recombination deficiency (HRD) and show clinicopathological and genomic instability characteristics resembling those of BRCA1-mutated BCs. Moreover, we observed that in the early disease setting, HORMAD1-positivity was predictive for benefit of high-dose platinum-based chemotherapy (HDCT) compared to conventional non-platinum-based chemotherapy in a subgroup of patients with high-risk HER2-negative BC participating in the N4plus Dutch trial.
Last, we studied a subgroup of patients with eTNBC participating in the phase III FinXX trial, randomized between adjuvant capecitabine-containing and conventional chemotherapy. Adjuvant capecitabine appeared to improve recurrence-free survival in patients with non-BRCA1-like tumors, while this survival benefit was less clear in patients with BRCA1-like tumors.
Together, the work described in this thesis may, if confirmed in independent series, contribute to optimizing risk stratification of patients with eTNBC and may help to guide the allocation of (neo)adjuvant treatment strategies for individual patients.
PREFERENCES OF USERS OF VIDEO SERVICES: RESULTS OF A SOCIOLOGICAL STUDY OF THE REASONS FOR WATCHING VIDEOS “WITHOUT PLOT OR CONTENT”
Authors: GARAGANOV A.V. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, RAZOV P.V.
Published: July 2024

The article presents empirical results of studying the preferences of video service users, as well as the reasons for millions of video views “without plot and content”. The relevance of the studied problem from the point of view of media content consumption in the daily life of the active part of the population of the Russian Federation is substantiated. The most typical reactions of respondents were studied, the motives and social significance of this phenomenon were analyzed. The article presents the main dominants of the evaluative attitude among the respondents to the viewed content. The results of the study led to the conclusion that video services have become an important source of media and information flow that meets the information needs of young people.
THE SOCIAL CONTRACT: HISTORY AND MODERNITY
Authors: ZUBOV V.V. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation
Published: July 2024

In this publication the author, using methods of analysis, description, classification, comparative approach, as well as formal-dogmatic and case-oriented methods, conducts a detailed study of the contract theory in its cross-temporal context, which allows us to establish the actual relationship between the theoretical research of thinkers of the past and the implementation of contractual principles in real political practice. It is determined that many of the postulates of the founders of the contract theory over time were favourably received by supporters of limited government power and are just as positively assessed by them now, which is expressed in the development of the idea of social contract. Reviewing the current state of a number of national political systems from the point of view of their constitutional regime, the author shows that the constitutional system of democratic societies has the idea of a social contract as a deep basis. It is noted that, although the constitutions themselves or acts of constitutional significance may not contain a reference to the contractual concept, this idea very profitably expresses the derivative nature of state power from the will, interests and needs of society. In the final section of the main part, a position is put forward according to which it is the democratic regime that is most suitable for implanting the social contract model. It is also postulated that the democratic ideal of modernity is simply unthinkable without the idea of the state as a product of an agreement between civil society and public authorities. At the end of the article it is pointed out that the design of the social contract has undergone a certain evolution since its elaboration by outstanding European thinkers, and if previously the social contract was perceived as a way of transition to the condition of a state in general, now it is interpreted much more broadly. Among other things, the author draws attention to the fact that the construction of a social contract, assumed by its authors as a universal model, is not applicable to some political systems due to their civilizational characteristics.
INSTITUTIONAL MODELS OF SOCIAL PARTNERSHIP POLICY: FOREIGN EXPERIENCE, RUSSIAN PRACTICE
Authors: ILYICHEVA L.E. ,   Institute of Public Administration and Civil Service of the Russian Presidential Academy of National Economy and Public Administration, Moscow, Russian Federation, PARSHINA E.V. ,   Institute of Socio-Political Research of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences (ISPR FCTAS RAS),   Russian Academy of National Economy and Public Administration under the President of the Russian Federation, Moscow, Russian Federation
Published: July 2024

In the article, the authors determined that due to the variety of conditions, types, subjects, etc. of social partnership, the policy of such partnership is multivariate and can be typologized on various grounds, which allows to reveal its diversity and multivariance. At the same time, the typology carried out in the article showed that there is no single, suitable model of social partnership policy for all countries. Each of these models has its advantages and disadvantages and should correspond to a set of conditions reflecting the national characteristics of a particular country. The role of motivation on the part of not only the state, but, first of all, society for the formation and implementation of this policy is also great. In addition to the positive consequences, the policy of social partnership carries risks, such as: the risk of formalization of social partnership relations, the risk of violation of the principles of social partnership, etc.
KEY DRIVERS OF INCREASING THE ENTREPRENEURIAL POTENTIAL OF MILITARY PERSONNEL BEING DISCHARGED INTO THE RESERVE
Authors: WOLF K.V. ,   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, BUBNOV A.L.
Published: July 2024

Within the framework of this article, aspects related to the identification of relevant areas for increasing the entrepreneurial potential of military personnel being discharged into the reserve are studied. The key elements of the entrepreneurial potential of individuals were identified and the features of this phenomenon within the framework of the activities of military personnel were described. Recommendations have been put forward that relate to individuals who have recently been discharged from military service. Among them, measures are noted to increase the awareness of individuals about the possibilities of professional adaptation after retirement, psychological counseling and support for entrepreneurial initiatives. In addition, the direction related to the formation of skills for developing competencies and gaining knowledge by military personnel during re-socialization is of particular importance. Proposals were also put forward for those persons who have already started doing business. Among these proposals, aspects related to establishing interaction between military personnel in the role of entrepreneurs, providing consulting support and creating centers for attracting and integrating individuals with the same professional roles are highlighted. In the final part of the work, options were proposed for solving the problems faced by military personnel after being discharged into the reserve, as well as difficulties arising within the framework of entrepreneurial activities of representatives of the studied group. Based on this, a conclusion was formed about the presence of similar points among the identified groups of problems. In addition, the article also described possible prospects for increasing the entrepreneurial potential of individuals who are able to have a positive impact on certain aspects of the socio-economic environment.
RELATIONAL DATABASE OF CARTOGRAPHIC SCENES WITH ASSOCIATIVE PROTECTION
Authors: VERSHININ I.S. ,   Kazan National Research Technical University named after A.N. Tupolev - KAI, Kazan, Republic of Tatarstan, Russian Federation
Published: July 2024

This research paper presents the new approach to data organization and protection in relational databases of cartographic scenes. The proposed approach uses associative steganography, which combines the principles of steganography and cryptography to protect information. The proposed technique is based on the processing and storage of cartographic information in vector format, as well as on the use of SQL servers to organize data protection. The structure and properties of relations in a relational database are described in detail, including different types of objects and map layers, methods of their representation and encoding. Particular attention is paid to the structure of data representation, protection measures, including randomization of records and use of association-protected storage format for certain attributes. The paper includes a discussion of the differences between an associative-protected full-object map schema database and a point-object database, and presents an analysis of vectorization errors and their relationship to raster data quality. This research is of interest to specialists in the field of geographic information systems, cryptography, information security, as well as to all those who work with processing and protection of cartographic data.
ASSOCIATIVE PROTECTION OF NUMERICAL INFORMATION IN TEXT DOCUMENTS USING THE PARALLEL FRAMEWORK LIBRARY ON THE.NET PLATFORM
Authors: GIBADULLIN R.F. ,   Kazan National Research Technical University named after A.N. Tupolev - KAI, Kazan, Republic of Tatarstan, Russian Federation, VERSHININ I.S.
Published: July 2024

The paper discusses the development and analysis of an application designed to protect numeric data in text files using an associative data protection mechanism. The application, based on the .NET platform and using the Parallel Framework library, was tested in detail to evaluate the effectiveness of multithreaded data processing and the use of regular expressions to extract numeric information from text. The results showed that the application of parallel processing can significantly increase performance, achieving twice the speedup on a multi-core hardware platform. At the same time, the paper highlights and analyzes some of the challenges and limitations associated with parallel processing, including user interface locking, the need for thread safety, and the peculiarities of working with regular expressions in multithreaded mode. Possible directions for further improvement of the application are discussed. The conducted research is of practical value for the development of parallel data processing methods in the context of information protection.
THE DEVELOPMENT OF THE LOAD BALANCER AND THE PARALLEL MODULE FOR MANAGING ASSOCIATIVELY PROTECTED MAP DATABASES
Authors: VERSHININ I.S. ,   Kazan National Research Technical University named after A.N. Tupolev - KAI, Kazan, Republic of Tatarstan, Russian Federation
Published: July 2024

In the modern world, where information security and big data processing are key aspects of many industries, the importance of effectively managing and ensuring the reliability of cartographic databases is growing. These databases serve as the foundation for a wide range of applications, including geographic information systems, transportation management, environmental modeling, and urban planning. With the increase in the volume of geodata and the expansion of their use in various industries and science, the requirements for processing speed, accessibility and, above all, the security of this data are increasing. Poor management or security vulnerabilities can lead to significant losses, both economically and socially. The article is devoted to the development of a load balancer and a parallel module for managing associatively protected cartographic databases. The work includes a description and analysis of the use of the PostgreSQL DBMS with the Npgsql and PostGIS extensions for working with associatively protected spatial data. The article presents a method of parallel programming using the TPL library of the C# language. Testing of the developed module revealed optimal operating conditions, showing an increase in performance depending on the configuration of the nodes. The results of the study can serve as the basis for further optimization and development of systems for processing and managing large volumes of associatively protected geodata.