bluuebunny/crossref_metadata_2025 huggingface dataset:
PROJETO PRINCIPAL DE EDUCAÇÃO PARA A AMÉRICA LATINA E O CARIBE: REPERCUSSÕES NA EDUCAÇÃO LATINOAMERICANA
Authors: Cruz Bruno Nicolau Cerine da , Martineli Telma Adriana Pacifico
Published: February 2023

Este artigo é resultado de um estudo que investigou as repercussões das ideias produzidas a partir do Projeto Principal de Educação para a América Latina e o Caribe nas políticas educacionais e curriculares para a educação básica brasileira, chilena e uruguaia. O percurso metodológico foi delineado tendo como base a pesquisa documental, cujos documentos principais para a coleta dos dados foram as declarações, pareceres e relatórios referentes ao projeto. Os resultados da pesquisa indicaram que: 1) esse projeto orientou os rumos das reformas educacionais ocorridas em países da América Latina, como o Brasil, o Chile e o Uruguai; 2) as discussões e debates para as transformações da educação básica latino-americana, no contexto do projeto, fundamentaram-se em uma concepção de educação e desenvolvimento ancorada em uma perspectiva humanista e educativa do trabalho; e, por fim, 3) a década de 80 foi a fase de fundação e desenvolvimento das primeiras ações do projeto, com vistas à expansão quantitativa da educação básica, especialmente no número de matrículas, enquanto que a década de 90 foi intensificada as ações do projeto, com vistas, principalmente, à qualidade da educação, por meio de transformações na gestão e no currículo. Concluiu-se que o Projeto Principal de Educação teve suas ideias repercutidas nos três países pesquisados à medida em que os mesmos incorporaram e, ainda incorporam, os princípios e objetivos do projeto em suas respectivas políticas educacionais e curriculares, engendrando uma espécie de consenso entre as políticas educacionais e curriculares promovidas na América Latina.
A morte reconhecida: experiência de luto antecipatório de familiares de pacientes em final de vida
Authors: Magalhães Suzane Bandeira de , Daltro Mônica Ramos , Reis Tatiele Santos dos
Published: February 2023

O Serviço de Atendimento Domiciliar (SAD) presta cuidados paliativos domiciliares aos pacientes com câncer em estágio avançado e à sua família, nesse contexto inexoravelmente observa-se variados processos de lutos. O luto trata-se de um processo subjetivo, dinâmico, vivido de maneira singular pelo sujeito que perdeu algo/alguém importante para si. Assim, o objetivo foi compreender a experiência de luto antecipatório de familiares de pacientes oncológicos em terminalidade, acompanhados por um SAD, participaram do estudo 11 familiares de perfil heterogêneo. O método utilizado foi o Grupo Focal, cuja análise de conteúdo indicou que o luto antecipatório se processou a partir de três categorias: encontro com a gravidade da doença; família e cuidado; elaboração psíquica do luto antecipatório. Pode-se concluir que ser acompanhado pelo SAD demonstra ser elemento facilitador para elaboração do luto antecipatório e fator de proteção de um futuro luto complicado.
CINEIMOTION: UM MATERIAL EDUCACIONAL DIGITAL PARA IDOSOS CRIAREM FILMES EM STOP MOTION
Authors: Slodkowski Bruna Kin , Machado Leticia Rocha , Sampaio Deyse Cristina Frizzo , Grande Tássia Priscila Fagundes , Sigal Carla Bueno , Mendes Jozelina Silva da Silva , Behar Patricia Alejandra
Published: February 2023

O artigo objetiva apresentar o desenvolvimento de um Material Educacional Digital (MED) para auxiliar idosos a criarem filmes em stop motion. A cada ano aumenta o número de pessoas mais velhas interessadas em usar as tecnologias digitais e, com esse contexto, a necessidade de criar materiais diversificados para esse público. Um MED é um recurso que usa as tecnologias para ser criado e distribuído. Assim, o CineIMotionpermite o idoso ser autor de forma autônoma de filmes em stop motion. A metodologia foi qualitativa e considerou os 5 passos no método ConstruMED: Preparação, Planejamento, Implementação, Avaliação, Distribuição. O público-alvo foram idosos que participaram de um curso de extensão a distância em uma universidade brasileira no ano de 2021 [nome omitido para anonimato]. Para a coleta de dados, utilizou-se um questionário on-line referentes à avaliação do CineIMotion. Os participantes foram 27 idosos, 81,5% (n=22) do gênero feminino e 5,5%(n=5) do masculino. Os resultados obtidos demonstraram que 88,8% dos participantes avaliaram o MED como material possível de ser usado para construir um filme de maneira autônoma. Logo, entende-se que o CineIMotion traz como inovação para a educação dois aspectos: o primeiro se refere à disponibilização de um instrumento voltado à criação de filme em stop motion que pode ser utilizado por professores em cursos de inclusão digital, ou pelo aluno de modo autônomo. O segundo é a Comunidade CineIMotion que é um espaço aberto para o compartilhamento dos links dos filmes produzidos pelos idosos que utilizaram o material.
Agents of exploration and discovery
Authors: Langley Pat
Published: February 2023

Autonomous agents have many applications in familiar situations, but they also have great potential to help us understand novel settings. In this paper, I propose a new challenge for the AI research community: developing embodied systems that not only explore new environments but also characterize them in scientific terms. Illustrative examples include autonomous rovers on planetary surfaces and unmanned vehicles on undersea missions. I review two relevant paradigms: robotic agents that explore unknown areas and computational systems that discover scientific models. In each case, I specify the problem, identify component functions, describe current abilities, and note remaining limitations. Finally, I discuss obstacles that the community must overcome before it can develop integrated agents of exploration and discovery.
Expression Strategy of Soluble Recombinant Human TGF-β3 in Escherichia coli: sfGFP -Fusion Tag
Authors: BİLGİN Sema
Published: February 2023

Transforming growth factor-beta 3 (TGF-β3) is an important cytokine involved in various biological processes. TGF-β3 is used as a scar-reducing antifibrotic agent for acute and chronic wounds and fibrosing disorders. TGF-β3, a valuable therapeutic protein, is produced recombinantly in different expression systems. TGF-β3, produced in the Escherichia coli (E. coli) expression system, widely used due to its various advantages in recombinant production, is commercially available. However, the main problem encountered in protein expression in E. coli cells is the formation of an inclusion body. Various approaches have been developed to solve this problem. The use of a fusion tag is one of the most powerful strategies used to obtain protein in the soluble active form in the E. coli expression system. Superfolder GFP (sfGFP) is one of the fusion tags used to increase the solubility of the fusion partner in E. coli. In this study, TGF-β3 with sfGFP fusion tag (sfGFP-TGFβ3) was successfully produced in soluble form in E. coli BL21 (DE3) in high yield and purity for the first time. Purified protein was identified by western blot and SDS-PAGE. 20 mg of protein with 98% purity was obtained from 1 L of bacterial culture. It was determined that the obtained high purity protein did not have a cytotoxic effect on BJ normal human skin fibroblast cells. The impact of sfGFP-TGFβ3 fusion protein on wound healing was evaluated with in vitro scratch wound healing assay. The results showed that the sfGFP-TGFβ3 fusion protein produced in soluble form in the E. coli expression system has the potential to support the wound healing process.
Assessment of the Usability of a Composite Containing Boron Carbide for Shielding the Gamma Rays
Authors: AKAR TARIM Urkiye
Published: February 2023

Considering the negative effects on the environment and toxicity of lead, which has been widely used for gamma shielding for a long time in nuclear technology, studies have been focused on the development of various materials that can be used as an alternative to lead in gamma radiation shielding. In this research, a composite material containing magnetite and boron carbide (epoxy/magnetite/boron carbide) and gamma transmission technique which is emphasized in nuclear applications have been used for the study of gamma ray shielding. The radiation sources considered for this technique are the radioisotopes Am-241, Cs-137, Na-22 and Co-60, which are important in nuclear technology. The interactions between the composite material and gammas with 59.5, 511, 661.6, 1173.2, 1274.5 and 1332.5 keV energies were investigated separately by the Monte Carlo method, and the ability of the material to shield the radiations at these energies was investigated. Gamma rays, one by one, followed by using cross sections and determining the probability of interaction with the composite from the point they are emitted until they leave the system (through escaping or absorption from the system) in the Monte Carlo code, which is written to determine the linear attenuation coefficient, mean free path, half value layer and tenth value layer, among the radiation shielding parameters of the composite under investigation. The shielding parameters calculated using the simulation results were also calculated using the data obtained from the XCOM software, and the results were found to be compatible with each other. On the other hand, in order to better evaluate the usability of the composite as an alternative shielding material for nuclear applications in the studied energy range, a comparison was made with the shielding parameters of various materials available in the literature.
On Fibonacci (k,p)-Numbers and Their Interpretations
Authors: TAŞYURDU Yasemin , CENGİZ Berke
Published: February 2023

In this paper, we define new kinds of Fibonacci numbers, which generalize both Fibonacci, Jacobsthal, Narayana numbers and Fibonacci p-numbers in the distance sense, using the definition of a distance between numbers by a recurrence relation according to a new parameter k. Tiling and combinatorial interpretations of these numbers are presented, and explicit formulas that allow us to calculate the nth number are given. Also, their generating functions are obtained and sums formulas of these numbers with special subscripts are given by tiling interpretations that allow the derivation of their properties.
News Coverage of the COVID-19 Outbreak: Thematic Analysis of a Portuguese Quality Newspaper
Authors: Rodrigues Pedro
Published: February 2023

News coverage can play a vital role during public health crises, raising awareness about potential risks, informing about response efforts, and encouraging preventive behaviors. However, the COVID-19 pandemic has increased the precariousness of journalists while introducing new challenges in their work. This article presents the results of a thematic analysis of 612 news articles about the initial stages of the COVID-19 outbreak in Portugal, published in a Portuguese quality newspaper from January to March 2020. Results show the relevance of geographical and cultural proximity as news values in international coverage. While the quantification of cases and deaths was a prominent theme in international and domestic coverage, specific cases of infection were frequent in domestic news, while general epidemiological indicators were more often the main theme in international coverage. News about events in Portugal was also more focused on specific containment and mitigation measures, while international coverage found states of emergency and lockdowns more newsworthy. As for news sources, there was a clear dependence on public officials and press releases from Direção-Geral de Saúde as information sources. The experiences and opinions of people speaking as individuals and not on behalf of organizations were much less frequent.
Additional information for the manual annotation of the terpene synthase gene family in Melaleuca alternifolia (tea tree) v1
Authors: Voelker Julia
Published: February 2023

This protocol was created to be read in conjunction with the publication about the manual annotation of the terpene synthase (TPS) gene family in Melaleuca alternifolia (tea tree). It provides additional information regarding the computational methods mentioned in the manuscript, especially concerning specific commands for reproducibility of the methodology. When using and citing this protocol, please also refer to the original article publication as mentioned in the metadata section of this protocol.
Immunofluorescence for Primary Brain Cell Cultures v1
Authors: V Kumar Ashley
Published: February 2023

Here we describe a protocol to detect specific proteins by immunofluorescence on cells cultured as monolayers. The protocol has been tested on primary cortical neurons and primary astrocytes isolated from mouse cortical tissues.
İKLİM DEĞİŞİKLİĞİ VE MİMARİ MİRASIN KORUMA SORUNLARI: ŞİLİ PASKALYA ADASI ÖRNEĞİ
Authors: ELVAN Abdurrahman , KAHRAMAN Gülçin
Published: February 2023

21. yüzyılın en dikkat çekici sorunlarından biri iklim değişikliğidir. İklim değişikliği, doğal ve sosyal çevreyi doğrudan etkiler. Dikkate ihtiyaç duyulan aşamada, iklim değişikliği kültürel / mimari mirası ciddi şekilde tehdit etmektedir. Bu nedenle, kültürel mirasın korunması için iklim değişikliğine yönelik potansiyel tehditlerin belirlenmesi ve koruma yöntemlerinin uygulanması zorunludur. Başka bir ifadeyle, iklim değişikliği sonucu kültürel mirasın kaybolmaması potansiyel tehditler ve koruma yöntemlerinin yapılarak farkındalığın artırılması son derece önemlidir. Bu nedenle iklim değişikliği konusunda tedbirler almak ve kültürel mirasın korunmasına yönelik çalışmaların işlenmesi önemlidir. Bu çalışmada özellikle Paskalya adasının seçilmesinin nedeni ise, ulusal literatürde bu konuda bir çalışmaya rastlanmamıştır. Ayrıca, paskalya adası doğal güzelliklerinin iklim değişiklikleri ile tehlike altında olmasından dolayı ele alınmıştır.
Collagen Nanoyarns
Authors:   , Chikelu Chukwuemeka Wisdom , Han Lin , Schauer Caroline L.
Published: February 2023

Rotator cuff tendon (RCT) disorders are noteworthy because of their preponderance in the elderly, and the high surgical failure rates in cases presenting with massive tears. Surgical strategies include the augmentation of the repair site mechanically by various graft materials. However, challenges such as immune rejection, donor site morbidity, poor cell adhesion and induced chronic inflammation among others still exist, hence the need for biomaterial-based scaffold replacements which mimic the extracellular matrix (ECM) architecture. Hierarchical fibrous scaffolds (HFS) consist of nanoscale fibers arranged in larger macroscale structures, much in the same pattern as in native tissue such as tendon and bone. Creation of continuous macroscale nanofiber yarns has been made possible using modified electrospinning set-ups that combine electrospinning with techniques such as twisting, drawing, and winding. In this work, a modified electrospinning set-up was used to successfully create continuous type I collagen nanofiber yarns (CNY). Structural denaturation assessment of native collagen using circular dichroism (CD) spectroscopy showed that 60% of the triple-helical collagen content in CNYs was preserved. Crosslinking of CNYs significantly improved their mechanical properties as well as stability in buffered saline with no sign of degradation for 14 days. To tune the porosity of CNY scaffolds, a sacrificial nanofiber removal process was executed by spinning PEO-CNY composites from which PEO nanofiber component was dissolved out to create pores. HeLa cells and 3T3 fibroblasts cultured on porosity-tuned CNY (PT-CNY) showed improved cell adhesion, infiltration, and viability, with cells displaying the characteristic spindle-like morphology of cells grown on surfaces with aligned topography. Collectively, the results demonstrate the promising potential of collagen nanoyarns as a new class of shapable biomaterial scaffold and building block for generating macroscale fiber-based tissues.
Pelatihan pengelolalaan pembelajaran jarak jauh bagi guru pendidikan jasmani
Authors: Bayu Wahyu Indra , Waluyo Waluyo , Victorian Ahmad Richard
Published: February 2023

Salah satu perubahan besar dalam bidang pendidikan yang dibawa oleh Covid-19 adalah lingkungan pembelajaran di mana peserta didik menerima pembelajaran mereka. Peserta didik lebih banyak menghabiskan waktu di rumah karena sekolah ditutup, pemerintah menganjurkan untuk tetap di rumah, dan melakukan karantina wilayah. Pelatihan ini bertujuan untuk membatu guru pendidikan jasmani dalam mentransformasi proses pembelajaran selama pandemic Covid-19, dimana pembelajaran tatap muka untuk sementara ditiadakan dan diganti dengan pembelajaran jarak jauh. Teknologi informasi yang digunakan berupa sistem pebelajaran jarak jauh (PPJ). PPJ memungkinkan untuk melakukan pebelajaran secara jarak jauh tanpa terikat jarak, dimanapun dan kapanpun dapat mengakses pebelajaran tersebut. Pelatihan dan pendampingan pengenalan platform pembelajaran seperti Zoom, Google Meet, Google Classroom, Schoology, dan Edmodo selama tiga hari yang dilakukan secara virtual dengan peserta 50 guru pendidikan jasmani telah memberi dampak positif terkait pemahaman guru pendidikan jasmani terkait dengan media yang dapat digunakan dalam PJJ mata pelajaran pendidikan jasmani.
Peningkatan Sumber Daya Manusia (SDM) Guru Pendidikan Jasmani melalui pelatihan penyusunan program latihan dan sport massage
Authors: Suhartoyo Topo , Budi Didik Rilastiyo , Kusuma Indra Jati , Febriani Ayu Rizky
Published: February 2023

Meningkatkan sumber daya manusia yang berkualitas dan berdaya saing merupakan program prioritas nasional tahun 2020-2024. Tujuan kegiatan meningkatkan kualitas guru pendidikan jasmani dalam menyusun program latihan dan sport massage. Metode yang digunakan melalui offline workshop, pemberian modul program latihan dan video sport massage. Peserta pelatihan merupakan guru pendidikan jasmani yang tergabung pada Musyawarah Guru Mata Pelajaran (MGMP) Pendidikan jasmani berjumlah 15 orang. Instrument tes menggunakan uji kompetensi bentuk soal pilihan ganda 20 butir dan 5 butir soal essay. Data pretest diketahui tingkat pemahaman guru sebesar 20 %, data posttest diperoleh hasil peningkatan kualitas pemahaman sebesar 93,34%. Kegiatan pelatihan menunjukan peningkatan sebesar 73,34%, sehingga kegiatan berdampak positif dan efektif dalam meningkatkan kualitas pemahaman penyusunan program latihan dan sport massage.
Edukasi pencegahan dan penanggulangan kekerasan seksual berbasis media Booklet wilayah kerja Women Crisis Center Dian Mutiara Kota Malang
Authors: Rachmawati Windi Chusniah , Ratih Suci Puspita , Wahyuni Zubaidah , Harra Fina Adibatul Hasanah
Published: February 2023

Kekerasan seksual yang semakin marak terjadi saat ini cukup menjadi sorotan. Dimana di Kota Malang mengalami peningkatan kasus kekerasan seksual terhadap Ibu Rumah Tangga (IRT) hampir 3 kali lipat, sehingga dilakukan upaya preventif dengan memberikan edukasi terhadap kelompok terkait.Kegiatan pengabdian masyarakat ini mengusung metode Research and Development (R&D) dengan desain one group pre-test post-test.  Media yang dikembangkan berupa media cetak Booklet penanggulangan kekerasan seksual berdasarkan hasil media assesment yang telah dilakukan. Pengabdian masyarakat ini dilakukan dengan metode sosialisasi terkait dengan kekerasan seksual terhadap Ibu Rumah Tangga (IRT). Kegiatan ini membuahkan hasil positif dimana terdapat peningkatan pengetahuan ditinjau dari hasil pre-test dan post-test yang dilakukan.
Pendampingan penulisan karya ilmiah bagi mahasiswa olahraga untuk publikasi ilmiah
Authors: Supriatna Eka , Simanjuntak Victor , Yanti Novi , Perdana Rahmat Putra
Published: February 2023

Tulisan yang tertuang dalam karya ilmiah hendaknya merupakan kajian dari hasil penelitian ilmiah yang dapat dipertanggungjawabkan secara ilmiah. Tujuan kegiatan pengabdian ini dilakukan guna meningkatkan pengetahuan mahasiswa olahraga mengenai aturan tata tulis penulisan karya ilmiah yang akan dijadikan artikel serta di publikasikan. Kegiatan pengabdian ini dilakukan dengan dua tahap, tahap penyapaian materi dan tahap pendampingan, kedua kegiatan dilakukan secara tatap muka, dengan metode ceramah selanjutnya sesi kedua berupa pendampingan dan diskusi praktek menulis karya ilmiah. Subjek kegiatan pengabdian ini yakni mahasiswa jurusan ilmu keolahragaan FKIP UNTAN yang berjumlah 15 orang mahasiswa yang terdiri dari Prodi Pendidikan Olahraga dan Pendidikan Jasmani. Hasil kegiatan ini mahasiswa mulai paham akan aturan serta tatacara dalam menulis karya ilmiah dan bisa memulai menuangkanya dalam bentuk draf artikel. Dari beberapa kali pendampingan yang telah dilakukan, bimbingan penulisan karya ilmiah ini hanya sampai pada proses tahapan draft abstrak, hal ini dikarenakan mahasiswa harus didampingi terlebih dahulu untuk melakukan penelitian sebelum mengarah pada tahap menulis karya ilmiah. Selama proses pendampingan terlihat progress kemajuan mahasiswa, terutama dalam tatatulis yang lebih teratur sesuai dengan buku pedoman penulisan karya ilmiah, serta arah tujuan baik berupa metode serta tata cara penelitian.
Implementasi metode demonstrasi deteksi dini penyakit tidak menular pada pengetahuan dan keterampilan kader posyandu lansia
Authors: Gayatri Rara Warih , Wardani Hartati Eko , Tama Tika Dwi
Published: February 2023

Kader posyandu lansia di Kelurahan Temas belum sepenuhnya mandiri dalam melakukan deteksi dini penyakit tidak menular. Tujuan dari pengabdian masyarakat ini adalah meningkatkan pengetahuan dan keterampilan kader posyandu lansia di Kelurahan Temas, Kota Batu. Metode yang dilakukan adalah pelatihan dan demosntrasi. Tempat di pendopo Kelurahan Temas Kota Batu. Waktu pelaksanaan pada  Bulan September, 2021. Peserta sejumlah 15 orang yang merupakan kader posyandu RW 2. Variabel yang diukur adalah tingkat pengetahuan dan keterampilan deteksi dini PTM. Analisis menggunakan deskriptif sederhana yaitu persentase. Hasil pengabdian kepada masyarakat diperoleh bahwa ada perbedaan pengetahuan dan keterampilan sebelum dan setelah dilakukan sosialisasi. Diharapkan dari kegiatan ini adanya pemantauan secara berkala dan berkelanjutan untuk mencegah PTM  bagi lansia.
Sosialisasi membangun semangat berlatih bolavoli pada masa pasca pandemi bagi siswa peserta ekstrakurikuler
Authors: Sujarwo Sujarwo , Purnomo Arif
Published: February 2023

Pengabdian ini dilatarbelakangi oleh turunnya semangat berlatih atlet bolavoli pada ekstrakurikuler karena dampak pandemi Covid 19. Tujuan dilaksanakan sosialisasi ini adalah untuk memberikan pengetahuan kepada atlet bolavoli peserta ekstrakurikuler di SMK Negeri 1 Panajam Paser Utara Kalimantan Timur tentang semangat berlatih olahraga bolavoli pada masa pasca pandemi. Metode pengabdian menggunakan webinar secara online atau daring, pengabdian dilaksanakan pada tanggal 16 Desember 2021. Peserta dalam pengabdian berjumlah 23 orang. Pemateri diberikan oleh pelatih bolavoli dengan lisensi FIVB Internasional level 3. Evaluasi dalam pelaksanaan pengabdian ini menggunakan perbandingan mean rerata hasil pretest dan posttest tentang pengetahuan atlet terhadap semangat latihan bolavoli dalam masa pasca pandemi. Hasil pengabdian menunjukkan bahwa terjadi peningkatan pengetahuan atlet dalam membangun semangat berlatih pasca pandemi, dengan mean rerata pretest: 52.60, dan hasil posttest sebesar: 73.91. Terjadi peningkatan pengetahuan sebesar: 21.31. atau sebesar 0.21%. Semangat berlatih bolavoli pada masa pasca pandemi dipengaruhi oleh faktor atlet dan juga pelatih. Faktor atlet harus memiliki goal setting dan juga mental toughness dalam menghadapi kondisi latihan pada pasca pandemi. Sedangkan pelatih harus mampu memberikan kenyamanan dan motivasi berlatih pada saat berlatih. Kesimpulan bahwa upaya yang bisa dilakukan oleh siswa untuk menambah semangat adalah dengan latihan mandiri di rumah, untuk pelatih agar siswa bersemangat berlatih pada masa pasca pandemi dengan memberikan tugas dan program latihan mandiri ke siswa dan juga selalu memonitoring latihan yang dilakukan, sebagai upaya meraih target atau tujuan latihan bolavoli.
Prieto García-Seco, David (2021): Un eslabón recuperado de la lexicografía española. La impresión retocada del Diccionario académico de 1780, Madrid, Visor Libros, 123 pp. (Prólogo de Pedro Álvarez de Miranda).
Authors: Garriga Cecilio
Published: February 2023

Reseña de Prieto García-Seco (2021): Un eslabón recuperado de la lexicografía española. La impresión retocada del Diccionario académico de 1780, Madrid, Visor Libros, 123 pp. (Prólogo de Pedro Álvarez de Miranda).
Evaluating the Effects of Lidocaine Alone versus Combination of Lidocaine with Pethidine for the Intravenous Regional Anesthesia in Upper Limb Soft Tissue Surgery
Authors: Amini Afshin , Farbood Arash , Asadi Saman , Safari Heidar , Ranjbar Mahsa
Published: February 2023

Background: Intravenous regional anesthesia (IVRA) has been used as a common anesthetic technique for several types of operations. However, there are various concerns regarding the efficacy of this anesthetic method. The aim of this study was to evaluate the effects of lidocaine alone versus concomitant use of lidocaine and pethidine for the IVRA in upper limb surgery.
Methods: In this randomized, double-blind, controlled clinical, 50 eligible individuals were randomly divided to receive either a combination of 1.5 mg/kg lidocaine 2% and 1.5 mg/kg pethidine or placebo (3 mg/kg lidocaine 2%) for IVRA. After the surgery, the onsets and durations of sensory and motor block, the pain intensity in recovery room, the subjects' first demand of morphine, and the total amount of morphine injected within 24 hours were measured.
Results: The combination of lidocaine and pethidine was significantly effective in accelerating the onset of both sensory and motor blocks [(P=0.001), (P=0.001), respectively]. However, no differences were found between groups in sensory and motor block durations after surgery. Intervention with lidocaine plus pethidine caused a significant reduction of the pain intensity in recovery room (P=0.02). Also, concomitant use of lidocaine and pethidine led to a longer time of the first demand of morphine (P=0.04). Moreover, the total amount of morphine injected within 24 hours after surgery was considerably lower in individuals treated by lidocaine plus pethidine (P=0.003).
Conclusion: The results of the current study suggest that adding pethidine to lidocaine can be considered as an appropriate approach for better management of IVRA.
Intubation without Muscle Relaxant: The Role of Sevoflurane
Authors: Hajimohamadi Fatemeh , Yoosefi Abolghasem , Behzadi Mehrdad , Nazemian Yazdi Nader Ali , Abdollahi Hamed , Etemadi-Aleagha Afshar , Omran Samira Parvizi
Published: February 2023

Background: Sevoflurane is preferred for induction of general anesthesia in pediatrics. We examined the minimum duration of sevoflurane administration resulting in most optimal intubation conditions.
Methods: We included 75 children, aged 2-12 years, undergoing tonsillectomy under general anesthesia at Amir-Alam Hospital. They were given midazolam 0.05 mg/kg and fentanyl 2 mic/kg IV, five minutes before induction with sevoflurane 8% in 60% N2O and 40% O2 with total gas flow of 10 lit/min via face mask for 90 seconds (group I), 120 sec (group II) or 150 sec (group III), randomly. After tracheal intubation, intubation condition was assessed using Steyn's modification of Helbo Hansen scoring system. The total scores were divided into clinically acceptable (≤10) or unacceptable (>10).
Results: There was no statistically significant difference among the three groups in demographic characteristics. Mean ± SD of intubation scores were 10.04±2.9, 8.12±3.2, and 5.64±1.15 in groups 1-3, respectively (P<0.001) with statistically significant differences between all three groups: between groups I and II (P=0.044), I and III (P<0.001), as well as II and III (P=0.004). Intubation conditions were acceptable in 11, 16, and 25 patients in each group, respectively (P<0.001).
Conclusion: Inhalation induction by sevoflurane 8% in 150s provides acceptable clinical situation for intubation in pediatrics.
Perioperative Anesthesia Management of a Patient with Triplet Pregnancy Who Developed Hemorrhage Due to Uterine Atony during Cesarean Section: A Case Report
Authors: Kaya Deniz , Çekmen Nedim , Ayhan Asude
Published: February 2023

The incidence of postpartum hemorrhage (PPH) is increased in multiple pregnancies and is an important cause of maternal death. Controlling bleeding and correct anesthesia management during this period are essential.
In our 35-year-old patient with triple pregnancy, hemorrhage due to uterine atony developed during C/S surgery. We aimed to discuss the anesthesia management of PPH in our patient who underwent a total abdominal hysterectomy and bilateral salpingectomy (TAH BS) due to continued bleeding during and after C/S, with literature.
We think that morbidity and mortality rates can be reduced in the perioperative period for PPHs with the help of multidisciplinary approach, rapid action, and close follow-up.
Prime Solution and Administration of Albumin in Pediatric Heart Surgery
Authors: Jabbari Ali , Nooralishahi Behrang , Amirkhanlou Saeid , Khori Vahid
Published: February 2023

The Article Abstract is not available.
The linkage between prevalence of integron I and reduced susceptibility to biocides in MDR Klebsiella pneumoniae isolated from neonates
Authors: Samir Pola , Mohamed El-Baz Ahmed , Ibrahim Kenawy Hany
Published: February 2023

Background and Objectives: Klebsiella pneumoniae causes challenging nosocomial fatal infections including neonatal sepsis. Our study aims at clarifying the contribution of integrons in the observed reduced susceptibility of multidrug-resistant (MDR) K. pneumoniae isolated from septicemic neonates to the clinically used antimicrobial agents and biocides.
Materials and Methods: Eighty-six K. pneumoniae isolates were collected from Mansoura University Children’s Hospital from septicemic neonates. Isolates were subjected to antibiotic and biocide susceptibility using disk diffusion and the agar dilution method, respectively. The distribution of different classes of integrons was screened in the isolates by PCR. Detected inegron I was sequenced in selected isolates.
Results: Fifty-seven isolates (66.27%) were MDR. In the MDR isolates, class I integron was detected in 23 (40.3%), inte- gron III was detected in 20 (35%), whereas integron II could not be detected. Sequencing results of integron I from MDR K. pneumoniae isolates revealed that only aminoglycoside and folate synthesis inhibitors gene cassettes were detected, while the rest of the resistance genes were not associated with integron I.
Conclusion: The presence of integron I in MDR K. pneumoniae tested isolates may contribute only to some biocide resistance, however, it does not seem to be the only contributor in multiple drug resistance.
Expression and purification of MERS-CoV envelope protein, an essential viroporin, using the baculovirus expression system
Authors: Alsaadi Entedar , Alghezi Dhafer , Jones Ian
Published: February 2023

Background and Objectives: The causative agent of Middle East Respiratory Syndrome (MERS) is a zoonotic Coronavirus (MERS-CoV) identified in Saudi Arabia in 2012. The envelope (E) protein of MERS-CoV is a small viral protein which plays several essential roles during virus replication. To facilitate study of the structure and function of the E protein, recombinant MERS-CoV E protein was expressed using the baculovirus expression system.
Materials and Methods: A recombinant E open reading frame including an 8-histidine tag at the amino terminus was de-signed and cloned into a baculovirus transfer vector. Following construction of a recombinant virus insect cells were infected and the expression of the E protein assessed by SDS-PAGE and Western blotting.
Results: Recombinant E protein, tagged at the N-terminus with a polyhistidine sequence, with a molecular mass of 10.18 kD was identified by Western blotting with an anti-His antibody. Following large scale infection E protein was released by detergent mediated lysis of infected cells and purified by Immobilized Metal Ion Affinity Chromatography (IMAC).
Conclusion: Purified full length recombinant MERS-CoV E protein can be isolated by IMAC and is suitable for further functional, biophysical or immunological studies.
Prevalence of herpes simplex viruses types 1 and 2 infections among suspected children of encephalitis in Kermanshah, Iran
Authors: Fakhredini Kamal , Soleimanjahi Hoorieh , Bamdad Taravat
Published: February 2023

Background and Objectives: Various infectious and non-infectious factors can cause encephalitis in the central nervous system (CNS), the most important of which are viruses. Herpes viruses are one of the most important causes of encephalitis worldwide. PCR detected the virus on the cerebrospinal fluid (CSF) sample. The aim of this study was to set up an in-house PCR to identify herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) and determine the prevalence of these viruses in suspected children of encephalitis.
Materials and Methods: This cross-sectional study was conducted on 160 suspected children with encephalitis cases re- ferred to Dr. Kermanshahi Children Hospital, Kermanshah, Iran, from April to March 2021. CSF samples were extracted using a viral extraction kit, and a PCR was performed. The level of glucose and total protein of the samples was measured.
Results: The total prevalence of HSV was 16.25%. 17 samples were positive for HSV-1 (10.6%), and 9 samples for HSV-2 (5.6%). There was a significant correlation between glucose, total protein, and HSV PCR positive, but no significant correlation between age and HSV PCR positive results.
Conclusion: Rapid diagnosis of a virus may reduce the hospitalization rate and the use of unnecessary therapies and crease mortality, morbidity, and disability in children. Results in this study show that the distribution of HSV types in children with encephalitis predominantly was type 1 compared with type 2.
Comparative evaluation of the antioxidant potential of rainbow trout exposed to Yersiniosis vaccine and non-vaccinated fish
Authors: Sadighara Parisa , Araghi Atefeh , Molaee-Aghaee Ebrahim , Erfanmanesh Ahmad , Pirhadi Mohadeseh , Farkhondeh Tahereh
Published: February 2023

The antioxidant capacity of liver in fish is a major property which could prevent the diminished quality and safety of fish resulted from oxidation reactions. The aim of this study was to compare the antioxidant capacity of the liver of rainbow trout exposed to the yersiniosis vaccine and nonexposed fish. The amounts of carotenoids, glutathione, cupric assay, and lipid peroxidation levels of liver were determined. Then, the samples were normalized by Bradford test. The results showed that significant differences may exist in lipid peroxidation level (p<0.05). The total antioxidant capacity, glutathione, and carotenoids content showed no significant difference in both group (p≥0.05). The use of vaccine, in addition to increasing resistance to yersiniosis, could prevent the lipid oxidation of fish liver.
The Role of the Governor in the Local Government Administration System in Indonesia
Authors: Sarkawi Sarkawi , Ainuddin
Published: February 2023

Regional autonomy was born as an interesting idea as a form of correction of the style of government and the relationship between the center and the regions which is centralized, exploitative and far from democratic values ​​which are currently the mainstream of the prevailing political system in the world. 1.The Role of the Governor Philosophically, Based on the various explanations above, it can be concluded that the philosophical reconstruction of the position and role of the Governor must be based on the spirit of the existence of the Governor to safeguard the Unitary State of the Republic of Indonesia so that therefore the role and position of the Governor must be clear, namely as the Representative of the Central Government in the regions and As Regional Head. 2.Theoretical Role of the Governor, Governors must guarantee the implementation of the vision and mission of the central government, especially general administration tasks such as national stability and integration, government and development coordination, and supervision of district/city government administration. As a consequence, a systematic arrangement is needed that describes a tiered relationship, including supervision, guidance, and coordination of administration and development in districts/cities. 3.The Normative Role of the Governor, Government that involves the involvement of various parties in an area based on the aspirations of the local community, then government affairs which are the authority of the central government are partially handed over to regional governments to be managed as their own household affairs. Therefore, philosophically the emphasis on regional autonomy remains at the district/city level, this is based on the possibility of a federal concept occurring if regional autonomy is emphasized at the provincial level but the Governor is given a bigger role and stronger authority as a representative of the central government in especially in relation to supervision and budget allocation.

Keywords: Regional Autonomy, Role of the Governor
Avaliação de modelos de energia para simulação numérica do comportamento mecânico de multifilamentos de poliéster
Authors: Cruz Daniel Magalhães da , Popiolek Júnior Tales Luiz , Barreto Marcelo de Ávila , Guilherme Carlos Eduardo Marcos , Stumpf Felipe Tempel
Published: February 2023

Os sistemas de amarração feitos de cordas de fibra sintética e, em particular, os de poliéster, ganharam destaque nas últimas décadas. Porém o comportamento mecânico de tais fibras tem suas complexidades para simulação em virtude da viscoelasticidade e das não linearidades material e geométrica. Simulações numéricas do comportamento mecânico do material utilizado em sistema de ancoragem são realizadas com base na teoria viscoelástica e, para isso, são utilizados dados experimentais para a calibração do modelo. A abordagem matemática viscoelástica da simulação numérica depende da função energia de deformação que, para multifilamentos de materiais poliméricos, possuem características como viscoelasticidade e incompressibilidade. O objetivo desse trabalho é estudar diferentes modelos de energia de deformação aplicados à simulação numérica do poliéster, material utilizado em ancoragens offshore. Como resultados, obtém-se uma comparação quantitativa entre os modelos no que diz respeito à qualidade dos ajustes matemáticos.
Modelo de negócio inovador por meio de aliança com distribuidores para criação de valor no setor de iluminação
Authors: Moraes Jr Laercio Ferreira , Ghobril Alexandre Nabil
Published: February 2023

O mercado de iluminação movimenta no Brasil cerca de R$ 3 Bilhões anuais e tem mudado de forma expressiva após a introdução do LED, permitindo a participação de diversos novos entrantes, fato que tem dificultado o crescimento de negócios e pressinada a rentabilidade de multinacionais líderes no segmento.  Esse mercado tem como característica a importação de lâmpadas, luminárias e sistemas de controle de iluminação e estima-se que possui mais de 600 concorrentes que buscam vendas com produtos muito equalizados tecnicamente. Nesse sentido, os fabricantes estão colocados em uma situação que cada vez mais os pressiona para trabalhar com margens menores comprometendo a rentabilidade do negócio, fato que tem levado alguns fabricantes a desistirem do segmento de iluminação no Brasil. Com o intuito de perpetuar os negócios de um desses fabricantes que é pioneiro no negócio de iluminação e um dos líderes globais, encontrou-se um oportunidade não explorada até o momento de se oferecer uma solução a clientes finais através do canal de distribuição da empresa. Neste trabalho, apresenta-se um relato técnico do processo de criação de valor no negócio de iluminação através de uma aliança formada entre fabricante e distribuidor, baseada na oferta técnica e compartilhada de serviços de atendimento especializado, pré-venda e pós-venda. Partindo-se de uma análise de mercado, seguiu-se para a validação do projeto internamente na companhia e com alguns de seus principais parceiros de negócio, o que culminou em um projeto piloto passível de replicação a nível nacional. A proposta de solução possui potencial de mercado, risco relativamente baixo frente ao negócio e permite benefícios aos envolvidos no campo de rentabilidade, parceria, melhoria na percepção de marca e atração de clientes que puderam ser confirmados pelos resultados obtidos.
Elementy sztuki Kolchida-Koban w scytyjskim stylu "zwierzęcym"
Authors: Avalishvili Gia
Published: February 2023

Kultury Europy i Azji znane jako scytyjskie uformowały się nie wcześniej niż w końcu VII i na początku VI w. p.n.e. Powstanie scytyjskiego stylu zwierzęcego miało miejsce po przybyciu Scytów w rejon Kaukazu. Wtedy również w tym stylu pojawiły się elementy sztuki Kolchida-Koban, głównie w zakresie plastyki figuralnej.
Koszty budowy fortyfikacji murowanych w Polsce do XVI wieku
Authors: Szymczak Jan
Published: February 2023

W artykule podjęto próbę określenia wielkości wydatków na budownictwo obronne, a to miejskie mury obronne oraz zamki, zarówno o charakterze wybitnie wojskowym, jak i rezydencjonalno-obronnym. Koszty budowy i naprawy umocnień miejskich ponosił ich właściciel, ale partycypowali w tym także mieszczanie – jak wskazują przykłady Wrocławia z przełomu XIII i XIV w. oraz Krakowa i Lwowa w XV w. Nakłady finansowe na fortyfikacje w niektórych latach stanowiły dość znaczne obciążenie dla budżetu miejskiego.
Koszty budowy zamków uzależnione były od wielkości obiektu i jego wyposażenia. Zamek biskupa krakowskiego Zbigniewa Oleśnickiego w Pińczowie kosztował w III ćwierci XV w. ponad 20 tys. grzywien, na mniejsze założenia obronne wydatkowano 12 tys. grzywien, zaś niewielkie rezydencje rycerskie można było wznieść za 500-700 grzywien. Kolejnym problemem jest rozbudowa i modernizacja oraz naprawa zamków. Gruntowna przebudowa zamku łęczyckiego w latach 1563-1564 oceniona została na 3 tys. florenów.
Na koszty budowy i naprawy fortyfikacji składały się przede wszystkim wydatki na materiały budowlane, ich transport oraz płace robocze. Według przeprowadzonych obliczeń odcinek muru ceglanego o kubaturze 1 m3 zawierał materiały budowlane za 9 groszy w końcu XIV w., aby w II połowie XVI w. osiągnąć 22 grosze. W świetle rachunków z XVI w. płace stanowiły 31% wszystkich kosztów, na transport poszło 20%, natomiast materiały budowlane wynosiły pozostałe 49% wydatków.
Budownictwo obronne należało do inwestycji bardzo kosztownych i angażowało znaczną część dochodów szlachty, możnowładztwa oraz panującego. Fortyfikowanie kraju przez Kazimierza Wielkiego pochłonęło około 524 tys. grzywien, co równało się wielkości wszystkich dochodów króla z okresu 7,5 lat jego panowania. Zapoczątkowany przez niego rozmach w budownictwie obronnym załamał się wszakże po jego śmierci, a wieki XV i XVI to czasy przeważnie inwestycji prywatnych.
The Promise and Limitations of Information Technology for Tax Mobilisation
Authors: Scarpini Celeste , Okunogbe Oyebola , Santoro Fabrizio
Published: February 2023

As digital technologies continue gaining momentum in Africa and lower-income countries, more and more tax authorities are adopting them to improve their core functions and collect revenue more efficiently. This paper reviews recent literature on using technology for tax administration. Technology has the potential to improve tax collection in three areas: identifying the tax base, monitoring compliance, and facilitating compliance. But even the most user-friendly technology will hardly function without basic infrastructure and a stable internet connection. The potential benefits of new technology are further hampered by resistance from taxpayers and collectors, an unsupportive regulatory environment and lack of strategy for adoption by institutions. We close by proposing reforms to ensure investments in new technology improve efficiency and revenue collection.
Ali Suad’ın “Dinî Edebiyat” Başlıklı Makalesinin Türk Dinî Edebiyatındaki Yeri
Authors: AYDIN SATAR Nesrin
Published: February 2023

İslami Türk edebiyatı hakkında derli toplu bir inceleme yapabilmek için, Türk dinî edebiyatına dair öncü çalışmalar oldukça önemlidir. Dinî edebiyat kavramının Türk edebiyatı içindeki anlamı ve yerinin saptanması, söz konusu öncü çalışmaların değerlendirmesiyle mümkün olabilir. Türk dinî edebiyatı üzerine düşünen öncü makalelerden biri olan ve Ali Suad tarafından Mihrâb mecmuasında kaleme alınan “Dinî edebiyat” başlıklı makale de Türk dini edebiyatını teorik olarak konu edinen erken makalelerdendir. Yazarın ilgili makalesine odaklanan bu çalışmada ise henüz 1920’lerin başında dinî edebiyatın iki farklı döneme ayrıldığını ortaya koyan bir Osmanlı aydınının Türk dinî edebiyatı hakkındaki düşünceleri tartışılmıştır. Çalışmada ayrıca, Ali Suad’ın “mutlak” ve “mukayyed” kavramlarını kullanarak ayırdığı, Türk edebiyatının eski ve yeni dönemlerinde kaleme alınan eserler ve bu eserleri üreten edebî şahsiyetlerden bahsedilmiştir. Çalışmanın sonunda Türk dinî edebiyatının Türk edebiyatı içindeki yeri, Türk dinî edebiyatının teorik arka planını kuran metinlerden biri olan “Dinî edebiyat” makalesine odaklanarak sorgulanmıştır.
Adjusting Class Policies amid a Pandemic: How Lessons Learned During COVID-19 Can Help Faculty Prepare for Other Institution-Wide Crises
Authors: Holtzman Mellisa , Whitehead Ellen , Welch Ayrlia
Published: February 2023

Research consistently suggests that student learning is maximized when faculty balance stringency and leniency in their classroom policies. However, the COVID-19 crisis raised an important question: In the face of a wide-scale crisis, should faculty instead adopt forgiving policies? This study uses interview data with 43 university faculty across the United States to examine policy adjustments made in response to COVID-19, as well as the impact faculty felt those adjustments had on course learning objectives. Results suggest that even amid a wide-scale crisis, balancing leniency and stringency offers benefits to both students and instructors. Implications for future crisis-response and crisis-preparedness are also discussed.
A zona portuária de Pelotas [RS]
Authors: Coelho Jossana Peil , Michelon Francisca Ferreira , Nogueira Cláudia da Silva
Published: February 2023

A zona portuária de Pelotas/RS é um testemunho de um período no qual a cidade contava, economicamente, com a presença ativa de muitas indústrias. Após o declínio do porto, tornou-se cenário de espaços fabris ociosos com uso restrito, por vezes, nada além de ocasional, apesar de se constituir em uma zona de proteção patrimonial. Reserva-se especial atenção a algumas trajetórias históricas e certas ações que, com a recente reativação do porto, foram surgindo, promovendo novas ocupações e articulando diferentes atividades. A partir de um conjunto de espólios fabris observa-se como esteve, possivelmente, relacionado o fim da concessão do Porto ao Estado do Rio Grande do Sul com o fechamento de várias indústrias e como na sua progressiva reativação, que se passa no presente, uma nova configuração de paisagem se insurge, anelada ao patrimônio e à cultura. Conclui-se sobre confluências que indicam possibilidades de ocupação dos amplos bens do patrimônio industrial e os reflexos que se venha a ter por isso no desenvolvimento do bairro.
Transportes mediados
Authors: Silva Diogo de Moraes
Published: February 2023

Em atenção às diferenças observadas entre os regimes de produção e fruição das obras de arte e dos índices materiais não ocidentais, este texto estabelece nexos interculturais referentes às relações sociais intermediadas por coisas. Para isso, coteja o regime estético com ponderações críticas acerca da autonomização da obra de arte na modernidade, e o correlato expurgo de sua dimensão funcional. O caráter autocentrado da arte é, assim, confrontado com a função agentiva inerente ao universo material cultivado por sociedades originárias. Desse exercício é derivada uma zona de contágio interpretativo, dentro da qual transita uma obra representativa da produção artística contemporânea.