bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Sea Surface Temperature and Chlorophyll-A and Its Relationship with Catch Results Flying Fish Eggs in the Waters of the Kei Islands
Authors: Retraubun Alex S. W , Tubalawony Simon , Masrikat Julius A. N. , Hukubun Ronald Darlly
Published: January 2024

The Kei Islands water area is quite productive in fisheries management. Environmental characteristics and oceanographic factors in a body of water will determine the potential of fisheries resources in a water body, and influence fish movement patterns and the formation of fishing areas for flying fish eggs. This research aims to examine the distribution of sea surface temperature and chlorophyll-a concentrations and analyze the relationship between sea surface temperature and chlorophyll-a concentrations with catches of flying fish eggs. The research focused on the waters of the Kei Islands, Southeast Maluku, which is an area for catching flying fish eggs. The research data was studied in the period December 2014 – November 2017. SPL and Chlorophyll-a data were downloaded from Citra MODIS-Aqua, while data on flying fish egg production was obtained from PPN Tual. The research results show that the monthly average SST distribution is between 25.03-30.42ºC, and the monthly average of chlorophyll-a varies quite widely with a range of 0.05-3.09 mg/m3. The number of flying fish egg production fluctuates every year with a production range of 36.28-81.905 kg. The peak of catching flying fish eggs occurs in June-September (eastern season and transition season II). The results of the analysis show that the correlation between SST and chlorophyll-a variables has a very dominant influence on the abundance of flying fish eggs.
Proporsi Konsumsi Junk Food dan Status Gizi Berlebih di Mahasiswa Kedokteran
Authors: Bestari Yuniah  , Yudi Feriandi  , Fajar Awalia Yulianto
Published: January 2024

Abstract. Overnutrition status in Indonesia has increased, from 14.8% (2013) to 21.8% (2018). The cause of excess nutritional status is an excessive intake of junk food. Current technological advances make it very easy to consume junk food through online food delivery services. Students consume junk food through online food delivery services, which has been increasing during the Covid-19 pandemic. The purpose of this study was to examine the Relationship between Junk Food Consumption through Online Food Delivery and Overnutrition Status among Students of the Faculty of Medicine, Islamic University Bandung. This study used a cross-sectional design approach. This research was conducted in January-December application for 62 respondents. The technique of sampling in this study used a stratified random sampling technique. The data were analyzed by the Fisher's Exact test. The results showed that students who often consumed junk food (83.9%) were more than people who didn’t consume junk food (16,1%). In the group which contains students who consume junk food, the proportion of excess nutritional status (100%) was greater than the group that rarely consumed junk food (30%). Efforts need to be made to increase awareness of controlling food orders through online food delivery to maintain a balanced nutritional intake.
Abstrak. Status gizi berlebih di Indonesia mengalami peningkatan, dari 14,8% (2013) menjadi 21,8% (2018). Faktor penyebab status gizi berlebih yaitu asupan makanan junk food yang berlebih. Kemajuan teknologi saat ini sangat memudahkan untuk mengonsumsi junk food melalui layanan online food delivery. Mahasiswa mengonsumsi junk food melalui layanan online food delivery yang semakin meningkat di masa pandemi Covid-19. Tujuan penelitian ini adalah untuk meneliti Hubungan antara Konsumsi Junk Food Melalui Layanan Online dengan Status Gizi Berlebih pada Mahasiswa Fakultas Kedokteran Universitas Islam Bandung. Penelitian ini menggunakan pendekatan dengan design cross sectional. Penelitian dilakukan pada Januari‒Desember 2022 terhadap 62 responden. Pengambilan sampel pada penelitian ini menggunakan teknik stratified random sampling. Data dianalisis dengan menggunakan uji Fisher’s Exact. Hasil penelitian menunjukan bahwa mahasiswa yang sering mengonsumsi junk food 83,9% lebih banyak dibandingkan dengan yang jarang mengonsumsi junk food 16,1% dimana dalam kelompok yang sering mengonsumsi junk food persentase status gizi berlebihnya 100% lebih besar dibandingkan kelompok yang jarang mengonsumsi junk food 30%. Perlu dilakukan upaya-upaya untuk meningkatkan kesadaran mengontrol pemesanan makanan melalui online food delivery untuk menjaga asupan gizi seimbang.
Karakteristik Demografi dan Klinikopatologi Pasien Kanker Paru di RSUD Al−Ihsan
Authors: Aida Fitriyane Hamdani  , Wida Purbaningsih  , Widhy Yudistira Nalapraya
Published: January 2024

Abstract. Based on the 2020 Global Burden of Cancer (GLOBOCAN), it is estimated that there are 2.2 million people in the world suffering from lung cancer with a percentage of 11.4% of all cancer-related incidents, with a mortality rate of 1.8 million, or 18% of the total cancer-related deaths. In 2020, the incidence of finding new cases of lung cancer in Indonesia reached 34,783 cases. Meanwhile, the death rate reached 30,843 people, which is in first place. Al-Ihsan Hospital is one of them as a Cancer center or hospital which is a referral center for West Java residents. This study aims to look at the demographic and clinicopathological characteristics of people with lung cancer at Al-Ihsan Hospital, West Java in 2020 and 2021. This study used a retrospective descriptive observational method with a sample size measured using total sampling. From this study it can be concluded that of the 82 patients who met the inclusion criteria, there were 49 patients in 2020 and 33 patients in 2021 with the highest age group, namely 55−64 years and dominated by men. It can also be concluded that the characteristics of lung cancer patients based on clinical symptoms are the most commonly found, namely patients with shortness of breath and chest pain. Based on the type of histopathology, the most common type is non-small cell lung carcinoma. Meanwhile, based on staging with an average staging, namely staging IV.
Abstrak.  Berdasarkan Global Burden of Cancer (GLOBOCAN) tahun 2020, diperkirakan terdapat 2,2 juta penduduk di dunia menderita kanker paru dengan persentase 11,4% dari semua insiden yang berhubungan dengan kanker, dengan tingkat kematian 1,8 juta, atau 18% dari jumlah kematian yang berhubungan dengan kanker. Tahun 2020, kejadian penemuan kasus baru kanker paru di Indonesia mencapai 34.783 kasus. Sementara itu, angka kematiannya mencapai 30.843 jiwa yang berada pada urutan pertama. RSUD Al-Ihsan salahsatunya sebagai Cancer centre atau rumah sakit yang menjadi pusat rujukan warga Jawa Barat. Penelitian ini bertujuan untuk melihat karakteristik demografi dan klinikopatologi pengidap kanker paru di RSUD Al-Ihsan Jawa Barat pada tahun 2020 dan 2021. Penelitian ini menggunakan metode observasional deskriptif retrospektif dengan besar sampel yang diukur penggunakan total sampling. Dari penelitian ini dapat disimpulkan bahwa dari 82 pasien yang memenuhi kriteria inklusi terdiri dari 49 pasien tahun 2020 dan 33 pasien tahun 2021 dengan kelompok usia tertinggi yaitu 55−64 tahun dan didominasi oleh laki-laki.  Dapat disimpulkan pula bahwa karakterisitik pasien kanker paru berdasarkan gejala klinis yang paling banyak ditemukan yaitu pasien dengan sesak nafas dan nyeri dada. Berdasarkan jenis histopatologi, jenis yang paling banyak adalah non small cell lung carcinoma.  Sedangkan, berdasarkan staging dengan rata-rata staging yaitu staging IV.
Framing Buku Pernah Tenggelam Terhadap Fenomena Korean Wave
Authors: Indah Hasanah Arifah  , Muhammad Fauzi Arif
Published: January 2024

Abstract. Nowadays, Korean wave is growing in Indonesia, but there are also various phenomena of Korean wave that are contrary to Islamic law. Fuadh Naim, a former Korean wave fanboy, who wrote the book Pernah Tenggelam as a manifestation of da’wah bil Qalam towards Korean wave fans, realized this. The purpose of this research is to find out the selection of issues and highlighting aspect of Korean wave that Fuadh Naim wrote in this book, as well as to find out how the book Pernah Tenggelam criticizes the Korean wave phenomenon. This research uses qualitative research method with Robert N. Enmant’s model of framing analysis. Data collection techniques were carried out by observation and documentation. The result of this research shows that Fuadh Naim selects issue based on the choice of facts by focusing on brief history of the Korean wave; his ‘dark times’; the Korean wave phenomenon that is not in line with Islamic law; and the ideal condition of a Muslim. The highlighting aspects of Korean wave that Fuadh Naim did is by the kind of language that can limits the reader's perspective; placing facts explicitly; explaining in-depth; and using graphics. Meanwhile, his criticism is that following the Korean wave a part of imitating (tasyabbuh) the unbelievers, which is prohibited because there are many things are not allowed on contrary of the Islamic law.

Abstrak. Dewasa ini, korean wave semakin berkembang di Indonesia, namun juga terdapat berbagai fenomena korean wave yang bertentangan dengan syariat Islam. Hal ini disadari oleh Fuadh Naim yang merupakan seorang ex-fanboy korean wave, sehingga ia menulis buku Pernah Tenggelam sebagai bentuk dakwah bil Qalam terhadap penggemar korean wave. Penelitian ini bertujuan untuk mengetahui seleksi isu dan penonjolan aspek korean wave yang dilakukan Fuadh Naim dalam menuliskan bukunya, serta untuk mengetahui kritik buku Pernah Tenggelam terhadap fenomena korean wave. Penelitian ini menggunakan metode penelitian kualitatif dengan metode analisis framing model Robert N. Enmant. Teknik pengumpulan data dilakukan dengan observasi dan dokumentasi. Hasil dari penelitian ini dijumpai bahwa Fuadh Naim melakukan seleksi isu pada pemilihan fakta dengan berfokus membahas sejarah singkat korean wave, pengalaman ‘tenggelamnya’ dan fenomena korean wave yang tidak sejalan dengan syariat Islam, serta kondisi ideal yang seharusnya bagi seorang muslim. Penonjolan aspek korean wave yang Fuadh Naim lakukan adalah dengan memakai bahasa yang dapat membatasi perspektif pembaca, menempatkan fakta secara mencolok, memberi ruang lebih banyak, dan menggunakan grafis. Sementara kritiknya bahwa mengikuti korean wave termasuk bagian dari menyerupai (tasyabbuh) orang kafir yang dilarang karena di dalamnya terdapat hal-hal yang bertentangan dengan syariat Islam.
Peran Pengajian Asy-Syaamil dalam Peningkatan Pemahaman Fikih Ibadah Masyarakat Kampung Kihapit Barat
Authors: Kiky Fatmawati  , Hendi Suhendi
Published: January 2024

Abstract. Recitation is one of the places for people to study Islamic sciences in depth. The purpose of the establishment of Asy-Syaamil studies, it is hoped that the people present will get appropriate Islamic religious instruction and be able to practice it in everyday life. errors in worship are found in the people of West Kihapit Village, especially in terms of ablution, prayer and fasting. The study aims to find out how the role of Asy-Syaamil recitation in increasing the understanding of Jurisprudence of the Western Kihapit community which is present. This study used qualitative methods with data collection techniques through interviews, conservation and documentation. The results of this study obtained conclusions: (1) The Asy-Syaamil recitation program consists of 6 programs (2) Understanding the Jurisprudence of Worship of the congregation of Asy-Syaamil recitation mothers before participating in Asy-Syaamil recitation is on average lacking and there are still errors in worship (3) The recitation of Asy-Syaamil plays a role in increasing the understanding of the Jurisprudence of its worshippers, this is evidenced by the recitation of Ash-Shaamil the pilgrims of the study of mothers become aware of the true knowledge and discard the mistakes that they have been holding and knowing.
Abstrak. Pengajian merupakan salah satu wadah untuk masyarakat mempelajari ilmu-ilmu Islam secara mendalam. Tujuan berdirinya pengajian Asy-Syaamil diharapkan masyarakat yang hadir mendapatkan pengajaran agama Islam yang sesuai dan mampu mengamalkannya dalam kehidupan sehari-hari. Kekeliruan dalam beribadah ditemukan di masyarakat Kampung Kihapit Barat terutama dalam hal wudhu, shalat dan puasa. Penelitian ini bertujuan untuk mengetahui bagaimana peran pengajian Asy-Syaamil dalam peningkatan pemahaman Fikih Ibadah masyarakat Kihapit Barat yang hadir. Penelitian ini menggunakan metode kualitatif dengan teknik pengumpulan data melalui wawancara, obeservasi dan dokumentasi. Hasil penelitian ini memperoleh kesimpulan: (1) Program pengajian Asy-Syaamil terdiri dari 6 program (2) Pemahaman Fikih Ibadah jamaah ibu-ibu pengajian Asy-Syaamil sebelum mengikuti pengajian Asy-Syaamil rata-rata kurang dan masih ada kekeliruan dalam beribadah terutama dalam hal shalat, puasa dan wudhu. (3) Pengajian Asy-Syaamil berperan dalam meningkatkan pemahaman Fikih Ibadah para jamaahnya, hal ini dibuktikan dengan adanya pengajian Asy-Syaamil para jamaah pengajian ibu-ibu menjadi mengetahui pengetahuan yang sebenarnya dan membuang kekeliruan yang selama ini mereka pegang dan ketahui.
GESTÃO E INDUÇÃO DO TURISMO PARA O DESENVOLVIMENTO REGIONAL EM UNIDADE DE CONSERVAÇÃO: ANÁLISE DA PERCEPÇÃO DOS VISITANTES DO PARQUE NACIONAL DE SETE CIDADES
Authors: Nascimento Laércio Ramon da Silva , Rabêlo Neto Alexandre , Santos Alexandre Rodrigues , Silveira Shaiane Vargas da
Published: January 2024

O estudo analisou os antecedentes da gestão do turismo para o desenvolvimento do Parque Nacional de Sete Cidades na perspectiva do visitante, considerando que na perspectiva científica, pesquisadores
Meio ambiente e sustentabilidade: Efeitos da exploração mineral as margens do rio Parauapebas-PA
Authors: Cabral Marcos Vinicius Afonso , Araújo José Augusto carvalho de , Pontes Altem do Nascimento , Gomes Priscilla Brandao Nogueira , Silva Elissandra Lima
Published: January 2024

No Brasil, as principais áreas produtoras de minério de ferro são a região de Carajás (PA) e a região de Columba (MG). Na região de Carajás, houve avanços notáveis na industrialização, levando a um af
DOI DESATIVADO
Authors: Plastino Caetano Ernesto
Published: January 2024

DOI DESATIVADO
DOI DESATIVADO
Authors: Pessoa Jr Osvaldo
Published: January 2024

DOI DESATIVADO
Desenvolvimento Educacional na primeira infância
Authors:   , Barbosa Emilda de Freitas Fernandes
Published: January 2024

Este artigo focaliza a primeira infância, compreendida como os anos iniciais de vida, destacando não apenas os aspectos positivos, mas também os desafios enfrentados nesse período crucial de desenvolvimento infantil. Examina-se de maneira abrangente os obstáculos físicos, cognitivos, socioemocionais e linguísticos que podem impactar adversamente o crescimento saudável das crianças. No âmbito físico, são abordados problemas como a desnutrição e a falta de acesso a cuidados médicos adequados. O texto explora as barreiras cognitivas, incluindo a limitada disponibilidade de estímulos educativos e as disparidades na aquisição de habilidades básicas. Questões socioemocionais, como a falta de suporte emocional e oportunidades de socialização, também são discutidas. Além de destacar os desafios, o artigo propõe uma visão otimista ao discutir futuros projetos e iniciativas. Aborda estratégias e intervenções inovadoras que visam superar os problemas identificados, promovendo um ambiente mais propício ao desenvolvimento infantil. Enfatiza-se a importância de políticas públicas e programas sociais que priorizem o investimento na primeira infância. A discussão se estende a projetos que buscam melhorar o acesso à educação de qualidade, promover a saúde infantil e fortalecer os laços familiares. Ao concluir, o artigo destaca a necessidade contínua de esforços colaborativos entre governos, organizações não governamentais e a sociedade para assegurar um futuro mais promissor para as crianças durante a primeira infância.
UMA EXPERIÊNCIA COM O ENSINO DE EQUAÇÕES POLINOMIAIS DO PRIMEIRO GRAU COM O SOFTWARE GEOGEBRA NA PERSPECTIVA DOS FEEDBACKS AUTOMÁTICOS
Authors: PINHEIRO FERNANDA PACHECO , FERREIRA ROBSON DOS SANTOS , LACERDA ALAN GONÇALVES
Published: January 2024

A utilização das Tecnologias da Informação e Comunicação (TIC's) se mostra fundamental nos processos de ensino e de aprendizagem de Matemática, dadas as suas potencialidades e o fato de estarmos trabalhando com uma geração de alunos que pensam com tecnologia. Diante deste cenário, nosso objetivo foi evidenciar as potencialidades dessa atividade para a construção do conhecimento matemático, nas perspectivas do Coletivo Pensante de Levy (1993) e da Reorganização do Pensamento de Tikhomirov (1981). Para tal, construímos uma atividade com feedbacks automáticos no software Geogebra para explorar o conceito de Equação Polinomial do 1º grau utilizando o smartphone e aplicamos em uma turma do 8º ano do ensino fundamental, de uma escola no município de Breves.
Impact of web-based learning platforms on primary school students’ academic performance in the UAE: Exploring the digital frontier
Authors: Shana Zuhrieh , Naser Khadijah , Zeitoun Eman
Published: January 2024

The three-month quasi-experimental study examined the impact of Purple Mash, an educational website, on grade four students’ academic achievement and perception. The study involved 28 participants, divided into control and experimental groups. Initial assessment scores were similar between the groups, but after the intervention, the experimental group showed a significant increase in post-test scores compared to the control group. The experimental group achieved an average score of 89.9, while the control group scored 77.2. Additionally, the students reported high levels of satisfaction with the interactive learning experiences provided by Purple Mash. Based on these findings, the study recommends the development of dedicated websites for each lesson to enhance accessibility and improve academic achievement and student perception in information and communication technology (ICT) courses. The integration of various data sources, such as pre- and post-test scores, classroom observations, and interviews, supported the credibility and dependability of the research findings. This thorough approach allowed for a deeper understanding of ICT class dynamics and the establishment of robust conclusions. The findings of this study provide compelling evidence of the positive impact of Purple Mash, a web-based mathematics learning platform, on primary school students’ mathematics achievement.
Examination of secondary school students’ conceptual understanding, perceptions, and misconceptions about genetics concepts
Authors: Ojo Ayodeji Temitope
Published: January 2024

Genetics concepts is taught at secondary school to equip students with relevant knowledge to engage with related socio-scientific issues in order to make a reasonable decision. However, earlier research shown that students exhibited poor comprehension of this concept. Despite several interventions, this problem persists. This study was designed to examine senior school students’ conceptual understanding, perceptions and misconceptions about genetics concepts as well as the causes of the misconceptions identified. The mixed methods design was adopted, while 789 students participated. Five instruments were used, while data collected were descriptively and content-analyzed. The results revealed that 21.4% of the students understood genetics concepts, 27.6% did not, while 51.0% had misconceptions. Students had negative perception of genetics concepts (x =2.47) and genetics contents indicator was the major causes of students’ misconceptions (x =2.92) against the 2.50 threshold. The teaching and learning of genetics concepts should be supported with relevant instructional materials and detailed textbooks.
The Dance of Empathy and Understanding: Nurturing Rapport in the Counselor-Client Connection
Authors: Ramadhani Lusi , Karneli Yeni , Hariko Rezki
Published: January 2024

This article explores the analysis of individual counseling service strategies in relation to the counselor-client relationship. The research method employed in this study is a literature review analysis. The results reveal that counseling is a process of providing assistance through counseling interviews conducted by a professional counselor to individuals facing various problems. Individual counseling emerges as a core service within guidance and counseling, enabling clients to express their personal issues and find solutions. The counselor-client relationship is of utmost importance, requiring the counselor to establish rapport, trust, and effective communication with the client. Building a strong therapeutic alliance is crucial for successful counseling outcomes. The counselor-client relationship is dynamic and evolves over time, fostering trust, mutual understanding, and personal growth. Furthermore, maintaining appropriate boundaries and adhering to ethical standards are vital aspects of the counseling relationship.
MORPHOLOGICAL INVESTIGATION OF AFFIXES IN IMAGINE DRAGONS LYRICS
Authors: Wulandari Herlina , Al Fauzi Fatih , Ismaili Ismaili
Published: January 2024

This study was implemented to analyze the form of affixesâ€™ changes in three Imagine Dragons songs as a study source for intermediate English students. This study applied qualitative corpus analysis initially the data results are presented in tabular form. Indeed, presented a detailed description of the data found. This research used document analysis to collect data where documents were taken from electronic form specifically at the website address lirikterjemahan.id. The results of this study show 39 words that have an affixation process in three songs, 35 (89,7%) inflectional affixes, and 4 (10,3%) derivational affixes were found. First, inflectional affixes do not change the part of speech but change the grammatical function belonging to the suffix â€“s as plural, -es as plural, -â€˜s as possessive, -ing as progressive (continuous), and -ed as past. Second, derivational affixes that can change the part of speech belonging to noun suffixes change the word to a noun in the suffix â€“ness, -dom, -er, and adjective suffixes change the word to an adjective in the suffix -less. Â Keywords: Morphology, Derivational affixes, Inflectional affixes, Song lyric
Penanganan Masalah Remaja Melalui Sufi Parenting
Authors: Bahruddin  , Saleh Akhmad Hasan
Published: January 2024

Remaja merupakan masa perkembangan antara usia anak-anak dan dewasa. Pada masa ini, remaja mengalami pertumbuhan emosional yang tinggi, sehingga mereka mudah mengalami permasalahan-permasalahan sosial jika tanpa pendampingan dan pendidikan yang tepat di keluarga. Inilah peran orang tua dalam mengerem laju masalah kenakalan remaja. Secara umum penyebab kenakalan remaja bisa dipicu karena pergaulan bebas; menganggap dirinya sudah besar jadi melarang orang tua ikut campur dalam urusannya; selalu berfikir bahwa dirinya itu sudah besar sehingga berbuat sesukanya; adanya konflik; akibat terlalu jauh dalam berpacaran; kurangnya motivasi hidup dari orang di sekitarnya; dan kurangnya perhatian dari orang tua. Kondisi inilah yang membuat tim ini melaksanakan pelatihan Sufi Parenting dalam membantu menangani kenakalan remaja memberikan pembekalan bagi orang tua tentang pendidikan anak usia remaja.

Melalui pelatihan Sufi Parenting diharapkan para orang tua terbantu untuk menyiapkan diri dengan lebih cepat dan tepat sekaligus sebagai langkah penyelesaian masalah remaja yang sudah ada dan terjadi di Kabupaten Pamekasan. Kegiatan pelatihan mencakup materi tentang pendidikan anak khususnya tentang pengetahuan masalah anak, remaja dan seksualitas dalam keluarga dan masyarakat ditujukan pada remaja dan orang tua di Kecamatan Pamekasan Kelurahan Parteker, Kelurahan Patemon, Kelurahan Kolpajung, Kelurahan Bugih, dan Kelurahan Barurambat Kota Kabupaten Pamekasan telah terlaksana dengan baik. Kegiatan pengabdian kepada masyarakat mengenai pendidikan anak khususnya pengetahuan masalah anak, remaja dan seksualitas dalam keluarga dan masyarakat ditujukan pada remaja dan orang tua di kelurahan-kelurahan tersebut telah terlaksana dengan baik.
Utilidad del rastreo del déficit de vitamina D y efectos de la suplementación en población de bajo riesgo
Authors: A Bengolea , S Hasdeu , D Lev , V Sanguine
Published: January 2024

Objetivo
El objetivo de esta revisión sistemática es evaluar la utilidad del rastreo de hipovitaminosis D en población de bajo riesgo y los efectos de su tratamiento.
Métodos
Se realizó una revisión sistemática de RS y ECAS que evaluaron el impacto del rastreo de hipovitaminosis D y la eficacia de la suplementación de vitamina D. Se realizó una búsqueda amplia en la base de datos Epistemonikos, la cuál se construye mediante búsquedas periódicas en diversas bases de datos y se complementó con una búsqueda en Pubmed desde fecha de inicio de las bases de datos hasta el 08/09/2023.
De manera independiente y pareda se seleccionaron los estudios y extrajeron los datos. El riesgo de sesgo se evalúo con las herramientas RoB 2 y AMSTAR.
Los resultados se metaanalizaron utilizando el método del inverso de la varianza con un modelo de efectos aleatorios. También se evaluó el efecto de subgrupo utilizando el instrumento ICEMAN. La certeza de la evidencia fue evaluada con el enfoque GRADE.
Resultados
A través de las estrategias de búsqueda se identificaron 2444 RS y 1588 ECAS. De estas, se incluyeron en la síntesis 2 RS y 17 ECAS reportados en 48 referencias.
No se encontraron estudios aleatorizados que evaluaran la utilidad del rastreo. En relación con la efectividad de la suplementación de vitamina D, se sugiere que probablemente no tenga un impacto significativo en la mortalidad por todas las causas (riesgo relativo (RR=1.01), intervalo de confianza (IC) del 95%: 0.83 a 1.23, con moderada certeza en la evidencia), ni en la incidencia de eventos cardiovasculares (RR=1.02, IC 95%: 0.83 a 1.24, con moderada certeza en la evidencia), ni en el riesgo de fracturas (RR=0.84; IC 95%: 0.60 a 1.18, con moderada certeza en la evidencia), ni en el riesgo de caídas (RR=0.91, IC 95%: 0.73 a 1.13, con moderada certeza en la evidencia), ni en el riesgo de hospitalizaciones (RR=1.46, IC 95%: 0.70 a 3.03, con baja certeza en la evidencia), así como tampoco en el riesgo de desarrollar infecciones respiratorias (RR=0.95, IC 95%: 0.67 a 1.35, con baja certeza en la evidencia). Con respecto a la seguridad de la suplementación con vitamina D en la población con hipovitaminosis, se sugiere que podría no aumentar el riesgo de eventos adversos serios, litiasis renal o eventos adversos generales.
Conclusiones
Dada la ausencia de beneficios evidentes se concluye que el rastreo podría no ser útil y su implementación podría resultar en una alta tasa de sobrediagnóstico y sobretratamiento. En relación a la suplementación en individuos con hipovitaminosis, los resultados evidencian la falta de beneficios significativos en la mortalidad, eventos cardiovasculares o incidencia de cáncer. Tampoco se encontró una influencia significativa en la incidencia de fracturas o en el riesgo de hospitalizaciones, infecciones respiratorias y caídas.
Klasifikasi Tingkat Keparahan Korban Kecelakaan Lalu Lintas Di Kota Samarinda Menggunakan Algoritma K-Nearest Neighbor dan Naive Bayes
Authors: Salsabila Nabila Abda
Published: January 2024

Classification is the process of evaluating data objects to be included in a particular class from a number of available classes. The K-Nearest Neighbor algorithm is one of the algorithms used to classify an object against a new object based on its K nearest neighbors. Naive Bayes is a classification of data using probability based on the Bayes theorem with strong independence assumptions. This study aims to compare the accuracy of the classification results on traffic accident victim data in Samarinda City using the K-Nearest Neighbor algorithm and the Naive Bayes algorithm. The data used is data on the severity of traffic accident victims in Samarinda City from 2020 to 2021 with death and non-death classes and uses 6 independent variables, namely age, gender, victim's role, victim's vehicle, road status, and condition weather. The measurement of accuracy in classifying the K-Nearest Neighbor algorithm and the Naive Bayes algorithm uses a classification performance matrix. Based on the results of the study, the accuracy of the classification results of the K-Nearest Neighbor algorithm was obtained at 75.86%, while the Naive Bayes algorithm obtained an accuracy rate of 79.31%. From the results of this analysis, it can be concluded that the Naive Bayes algorithm works better than the K-Nearest Neighbor algorithm in classifying the severity of traffic accident victims in Samarinda City.
Perancangan Sistem Informasi Manajemen Berbasis Website Pada Program Studi Teknik Industri Universitas Mulawarman
Authors: Isal Andi , Yudi Sukmono  , Harjanto Arif
Published: January 2024

The current advancement in information technology has had a significant impact on information provision and management. The presence of the internet as the primary medium for accessing information has become a fundamental necessity in modern society. In the context of higher education, the Industrial Engineering Program is not exempt from challenges in disseminating and efficiently managing information. Vital information often gets scattered and is difficult to access, especially when conveyed through conventional methods such as physical bulletin boards or WhatsApp messages. This research is conducted using in-depth interviews with various stakeholders, including program chairs, administrative staff, faculty, and students. The findings of this research strongly indicate the need for the development of a more efficient information management system within the Industrial Engineering Program. As a proposed solution, a website will be developed with various key features, including announcement management, curriculum information, schedule management, administrative management, guidance management, and document archiving. The implementation of this system is expected to address several identified issues, such as limited accessibility to important information and inefficient management. Thus, the operational efficiency of the Industrial Engineering Program is expected to be significantly enhanced. The results of this research highlight the importance of adapting information technology in the constantly evolving context of higher education. In an era where information technology continues to advance, efforts to utilize it optimally in information management within educational institutions like the Industrial Engineering Program remain highly relevant. An efficient information management system can provide substantial benefits in enhancing the quality of information management within the Program
Identifikasi dan Analisis Risiko Kecelakaan Kerja di Workshop PT. Inti Bangun Mulya
Authors: Karim Abdul Alimul , Suluhasa Yoel Era , Sukmono Yudi , Fathimahhayati Lina Dianati
Published: January 2024

PT. Inti Bangun Mulya atau biasa disingkat PT. IBM merupakan sebuah perusahaan konsultan tambang batu bara yang bergerak pada bidang jasa eksplorasi, yang berdiri sejak 2018. Dalam melakukan kegiatannya PT. IBM menggunakan bor untuk mengambil sample batu bara, dan tak jarang alat bor mengalami kerusakan, maka dari itu PT. IBM memiliki workshop tersendiri untuk memperbaiki ataupun merakit alat bor. Pada kegiatannya dalam memperbaiki dan merakit alat bor, pekerja workhop PT. IBM sangat erat dalam kegiatan mengelas, memotong besi, menggerinda, mengebor serta merakit alat bor. Kegiatan-kegiatan tersebut memliki dampak yang berbahaya bila dalam pengerjaanya tidak dilakukan sesuai prosedur. Oleh karena itu perlu dilakukan identifikasi dan analisis potensi risiko serta sumber penyebab potensi risiko tersebut untuk dapat mencegah terjadinya kecelakaan kerja serta berbagai masalah yang dapat disebabkan oleh potensi bahaya di tempat kerja. Metode yang digunakan yaitu metode FMEA (Failure Mode and Effect Analysis) dan metode FTA (Failure Tree Analysis). Metode FMEA dilakukan untuk mengindentifikasi potensi risiko kecelakaan kerja yang ada di workshop PT. IBM sedangkan metode FTA dilakukan untuk mengidentifikasi sumber penyebab terjadinya risiko tersebut. Berdasarkan metode FMEA didapatkan 10 potensi risiko yang mungkin terjadi di workshop PT. IBM. Dari 10 potensi risiko tersebut dilakukan perhitungan RPN (Risk Priority Number) sehingga diperoleh 3 kecelakaan kerja yang memiliki nilai RPN tertinggi, yaitu serpihan las mengenai mata, serpihan gerinda terkena mata, tangan terkena gerinda, dengan nilai PRN secara berturut-turut 120, 120, dan 100. Dengan metode FTA didapatkan basic event atau sumber penyebab terjadinya 3 risiko tersebut secara keseluruhan yaitu Kelelahan, tidak fokus, tidak konsentrasi, pekerja tidak patuh arahan, tidak biasa menggunakan APD, APD tidak lengkap, ruang kerja berantakan, alat tidak memadai, tidak ada rambu K3. Saran yang dapat diberikan adalah mengadakan alat produksi yang memadai, menata ulang letak bahan dan alat produksi, membuat jam kerja dan jam istirahat dengan jelas, memberlakukan peringatan tegas kepada pekerja yang tidak melakukan pekerjaannya dengan benar dan tidak menggunakan APD, melakukan pelatihan mengenai K3, memasang rambu-rambu K3, melakukan pengadaan pada APD yang memadai memakai APD pada saat bekerja di workshop.
Синтез и in silico прогнозирование молекулярно-направленного анти-EGFR действия нового производного дигидроакридона
Authors: Епишкина А. А. , Богословская Е. В. , Пакина В. А. , Осипьянц А. И. , Куторкина Е. А. , Литвин Е. А. , Тумутолова О. М. , Блинов К. Д. , Скачилова С. Я. , Семелева Е. В. , Шимановский Д. Н. , Федосейкин И. В. , Толстов М. В. , Блинова Е. В. , Ших Е. В. , Блинов Дмитрий Сергеевич
Published: January 2024

В работе представлены результаты синтеза и прогнозирования молекулярно-направленного ингибиторного действия нового соединения дигидроакридона в отношении рецептора эпидермального фактора роста (EGFR) in silico. В результате смешивания, гомогенизации и нагревания в среде 50 % этанола эквимолярных количеств 9-амино-3,3-диметил-3,4-дигидроакридин-1(2H)-она и L-2-гидрокси-бутандиовой кислоты получено вещество 9-аминия-3,3-диметил-3,4-дигидроакридин-1(2H)-она L-2-гидрокси-бутандиоват (ЛХТ-17-19) c чистотой 99,8 %. В результате виртуального молекулярного скрининга установлено наличие в спектре эффектов соединения ингибиторные свойства в отношении ряда внутриклеточных мишеней — драйверов канцерогенеза, среди которых наибольшая вероятность показана для киназного домена EGFR. Докинг основания ЛХТ-17-19 с киназным доменом EGFR сопровождался формированием комплекса с высоким сродством и энергией связывания. Полученные результаты позволяют предполагать у соединения ЛХТ-17-19 наличие высокой противоопухолевой активности в отношении злокачественных новообразований, экспрессирующих EGFR.
Исследование действия новых гибридных соединений на основе рилузола на клеточных моделях бокового амиотрофического склероза
Authors: Лапшина Мария Александровна , Бачурин Сергей Олегович , Григорьев Владимир В. , Устюгов Алексей А. , Аксиненко Алексей Ю. , Штейнберг Даниил А. , Малеев Григорий В.
Published: January 2024

Рассмотрены некоторые возможности создания оригинальных конъюгатов препарата «Рилузол» с ключевыми структурными фрагментами фармакологически активных веществ с целью получения новых мультитаргетных соединений, способных одновременно действовать на несколько мишеней, участвующих в процессе развития бокового амиотрофического склероза. Проведена оценка действия рилузола, его производных (конъюгатов с другими фармакофорными фрагментами) и биоизостерных аналогов на высвобождение и обратный захват нейромедиатора глутамата нервными окончаниями на модели фракции синаптосом Р2 радиолигандным методом. Методом фиксации напряжения было также изучено действие всех синтезированных соединений на потенциал-управляемые быстрые Na+-токи нейронов головного мозга млекопитающих. Результаты лазерной конфокальной микроскопии позволили получить информацию о состоянии патогенного белка. Показано, что конъюгаты рилузола с тремя нейроактивными фармакофорными структурами, а именно, диметиламиноадамантаном, фенотиазином и тетрагидро-гамма-карболином, в 2 – 3 раза снижают патологическую агрегацию белка FUS (коэффициент агрегации в диапазоне 28 – 46 %). Биохимический анализ накоплений патологической изоформы белка FUS после дифференциального ультрацентрифугирования позволил сделать заключение о том, что соединение ТГ-2253 в наибольшей степени приводит к накоплению меченого белка в цитоплазматической, а не в цитоскелетной фракции.
Влияние реамберина на параметры нейропсихологического статуса пациентов с органическим расстройством личности и поведения
Authors: Браш Н. Г. , Симонова Н. В.
Published: January 2024

Проведена оценка параметров нейропсихологического статуса у пациентов с органическим расстройством личности и поведения на фоне стандартной терапии и терапии, дополненной реамберином. На I этапе обследованы 80 пациентов с диагнозом «Органическое расстройство личности и поведения», в сравнении со здоровыми добровольцами (n = 20). На II этапе было сформировано 2 контрольных группы пациентов и 2 — основных: в первую контрольную группу (I, n = 20) вошли пациенты с органическим расстройством личности и поведения в связи с травмой головного мозга, получавшие стандартную терапию согласно клиническим рекомендациям, во вторую контрольную группу (III, n = 19) — пациенты с органическим расстройством личности и поведения в связи со смешанными заболеваниями, получавшие стандартную терапию согласно клиническим рекомендациям; в основных группах (II, n = 25; IV, n = 16) комплекс стандартной терапии был дополнен реамберином, который вводили внутривенно капельно. В соответствии с целью исследования определяли параметры нейропсихологического статуса. В общей группе пациентов с органическим расстройством личности и поведения, по сравнению с группой здоровых добровольцев по результатам МоСА-теста зарегистрирована когнитивная дисфункция, снижение эффективности работы в 3 раза, слуховой кратковременной и долговременной памяти на 37 – 43 % и на 20 – 23 % соответственно (p < 0,05). При этом функциональный статус пациентов по шкале Лоутона коррелирует с индексом повседневной бытовой активности Бартел (r = 0,959). Дополнение к стандартной терапии органического расстройства личности и поведения в связи с травмой головного мозга реамберином более выраженно в среднем на 18,5 ± 4,0 % (p < 0,05) нивелирует когнитивную дисфункцию, в сравнении с психопатологией сосудистого генеза, подтверждая антиоксидантный и психокорригирующий эффекты препарата: зарегистрирована положительная динамика показателей по шкале МоСА и мнестических параметров, облегчающая редукцию клинических симптомов заболевания с позитивным влиянием на параметры шкалы GDS и способствующая переходу 40 % пациентов из категории больных с умеренными нарушениями памяти в категории легких и очень легких когнитивных расстройств, по сравнению с пациентами, получавшими стандартную терапию, в среднем на 32,5 ± 5,6 % (p < 0,05). Сделан вывод о необходимости дальнейших исследований препарата с целью анализа клинической эффективности и расширения показаний к назначению реамберина в психиатрии.
VI Съезд фармакологов России
Authors: Есипова Ольга Валерьевна
Published: January 2024

20–24 ноября 2023 года состоялся VI Съезд фармакологов России «Смена поколений и сохранение традиций. Новые идеи – новые лекарства».
Оценка лечебных свойств мазей на основе полисахаридов из гриба вешенки
Authors: Ставский Е. , Теплякова Т. , Надеев А. , Ставская А. , Жайворон А. , Ермаченко М.
Published: January 2024

Проблема местного (медикаментозного) лечения ран различного происхождения обострилась в связи с приобретением устойчивости к антибиотикам гноеродной микробиоты. Оценены лечебные свойства мазей, приготовленных на основе полисахаридов из гриба вешенки обыкновенной (Pleurotus ostreatus). В состав мазей, кроме полисахаридов, входили в качестве мазевой основы физиологический раствор, ланолин как эмульгатор и вазелин. Ранозаживляющую эффективность мазей оценивали на 3 группах здоровых неинбредных мышей колонии ICR обоего пола. Контрольной являлась группа мышей, леченных контрольной мазью сравнения Левомикон-ТФФ. Лечение мышей продолжали до момента заживления у них резаных кожных ран. Ежедневно во всех группах оценивали двигательную активность, аппетит, динамику заживления ран, через каждые 3 суток — изменение у мышей массы тела и гистоморфологически изучали резаные раны кожи. Определяли площади ран и процент их уменьшения, скорость заживления ран. Показано, что компоненты мазевых основ испытанных мазей — полисахариды из гриба вешенки, содержащиеся в разовых дозах мази в количестве 4,0 – 4,8 мг, не обладают токсичностью для экспериментальных животных. Полисахаридсодержащие мази обеспечивали заживление ран в опытных группах животных на 7 – 9 суток раньше по сравнению с мышами контрольной группы.
Практическое применение промышленного одноразового хроматографа
Authors: Гнеушев А. , Безбородова Д. , Мальцева О. , Бойко И.
Published: January 2024

Приведен краткий обзор отечественного промышленного жидкостного хроматографа Greenvan ПХ-180 (Россия) асептичного исполнения с точки зрения разработчика технологии и технолога. Описан практический опыт применения хроматографа в производстве вакцины. Хроматографическая система позволяет проводить процесс очистки в асептичных условиях и свести к минимуму риск микробиологической контаминации продукта.
El arte proletario en cuatro esculturas de Carmen Saco Arenas
Authors: Encinas Boyer Ximena Natalia
Published: January 2024

La presente investigación analiza la representación del arte proletario en cuatro esculturas de la artista limeña Carmen Saco Arenas (1882-1948). Basándonos en las declaraciones de la artista sobre su deseo de crear un arte proletario, y también en el desarrollo y problemática de este movimiento artístico que surge a partir del inicio de la revolución soviética, es que buscamos entender y explicar las condiciones estéticas y contextuales en que Saco Arenas produjo sus obras escultóricas. En primer lugar, se examina la vida de la escultora, enfocándonos en su formación artística, así como en su militancia política, para luego analizar el movimiento del arte proletario y sus características dentro de la doctrina marxista. En último punto se realiza un análisis formal de cuatro creaciones escultóricas de la artista, fechadas aproximadamente en la tercera década del siglo XX. Este estudio también nos permite tener algunas luces sobre cómo se desarrolló este movimiento internacional en el contexto local de la ciudad de Lima de aquella época. Como resultado se demuestra que Saco Arenas concibió una versión particular del arte proletario, siguiendo los valores esenciales de esta vanguardia, pero, a su vez, enmarcado en el contexto peruano de inicios del siglo XX e influenciado por el movimiento indigenista.
De Perú a Bolivia. Entre el anarquismo, el liberalismo radical y el vanguardismo literario, 1902-1918
Authors: Margarucci Ivanna
Published: January 2024

En la región andina, los procesos de difusión y recepción ideológica de las izquierdas han sido generalmente estudiados a partir de un modelo construido en función del área atlántica del continente. Antes que la inmigración europea, en el caso boliviano, las vías de circulación regionales fueron las responsables del arribo del socialismo y el anarquismo. Así, en el presente artículo, nos interesamos por reconstruir la vía de difusión regional trazada en el corazón de la región andina a instancias de algunos personajes que, entre 1902 y 1918, se desplazaron intelectual y físicamente desde Perú a Bolivia y viceversa. Sobre la base de un amplio corpus documental, plantearemos como hipótesis que su anarquismo confundido con el liberalismo radical y el vanguardismo literario junto al célebre Manuel González Prada a quienes todos ellos admiraron, constituyeron una contribución intelectual en el proceso de radicalización y emancipación ideológica del movimiento obrero y las izquierdas bolivianas.
Social representations of teachers on school-office mistreatment
Authors: Masagca Jimmy T. , Azanza Patrick Alain T. , Berces Jennifer A. , Marasigan Josephine C.
Published: January 2024

Social representations (SRs) of selected teachers on short- and long-term school-office mistreatment and how they react, retort and develop coping mechanisms related to the issues on ‘social justice’ in educational leadership or management. Using Moscovici’s SR theory, a method in the representational field that involved key respondent-interviews, storytelling (kwentuhan), and “associative network” approach among teacher-respondents selected by a snowball sampling technique from undisclosed schools in the Philippines. In exploring SR on mistreatment and coping mechanisms of teachers, polarity and neutrality indices were computed as synthetic measurements of evaluation and attitude implicit in the representational field of school-office mistreatment or abuses. In case studies, the small number of participants allow for particularization or illustration of the uniqueness of the individual cases as viewed by them when shared in groups of academics. Insights on teachers’ subject loading, teachers’ assignments in research and extension, office designations and other provisions on sabbatical leave, research fellowships and faculty exchange programs also presented as reactions or coping mechanisms after the episodes of mistreatment.
Interactive Dialogics and Accuracy Of Physics LKPD Materials Based on PBL to Improve Student’s Critical Thinking Skills in Business And Energy Materials
Authors: Wahyuni Nilta , Prastyaningrum Violin Candra , Sari Dwi Resta Maulita , Iswardani Fadia Arisma , Bisyri Ahmad Janukhi , Hidayah Hikmah , Mahardika I Ketut , Subiki Subiki
Published: January 2024

The concept of effort is closely related to the concept of energy. Energy can be interpreted as the cause of effort. However, effort can also cause energy changes. The purpose of this study was to determine how the motivation ability and accuracy of PBL-based Physics LKS improve students' critical thinking on the material of effort and energy. This study used a research and development planning methodology. The data collection technique used is avalidation sheet as a validator. In addition, to obtain relevant information about the assessment tool, use analysis techniques, calculation methods to calculate the average score of each component and literature research. Based on the results of the research assessed by material experts and media experts, PBL-based LKS on the material of effort and energy and its use in everyday life is in the appropriate category and this PBL-based LKS can alsoincrease student learning motivation, where they can be more interactive in understanding the material of effort and energy and can think critically. Students can also solve problems about effort and energy material well. The conclusion obtained in this study is that the quality of this LKPD meets very good criteria so that this LKPD can be declared valid and of high quality to be used as one of the teaching materials for high school physics of work and energy. This LKPD has produced teaching materials that are quite accurate.