bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin
Authors: Braeuer Russell R. , Zigler Maya , Kamiya Takafumi , Dobroff Andrey S. , Huang Li , Choi Woonyoung , McConkey David J. , Shoshan Einav , Mobley Aaron K. , Song Renduo , Raz Avraham , Bar-Eli Menashe
Published: April 2023

PDF file, 1717K, qRT-PCR of autotaxin and nfat1 mRNA after silencing nfat1 in A375SM melanoma cells
Supplementary Data from RETRACTED: Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis
Authors: Gilkes Daniele M. , Chaturvedi Pallavi , Bajpai Saumendra , Wong Carmen C. , Wei Hong , Pitcairn Stephen , Hubbi Maimon E. , Wirtz Denis , Semenza Gregg L.
Published: April 2023

Supplementary Data PDF file 764K, Supplementary Figure S1, HIF-1 dependent P4HA1 and P4HA2 induction Supplementary Figure S2, P4HA1 and P4HA2 knockdown inhibits breast cancer growth and metastasis Supplementary Figure S3, Collagen hydroxylase knockdown decreases collagen deposition in vivo Supplementary Figure S4, P4HA1 and P4HA2 knockdown inhibits growth and metastasis of MDA-MB-435 cells Supplementary Figure S5, Picrosirius red staining of mouse lungs Supplementary Figure S6, P4HA re-expression in HIF-deficient cells rescues collagen deposition and metastasis Supplementary Figure S7, DHB treatment of MDA-MB-231 Cells Supplementary Table S1, Real-time qPCR primers. Supplemental Table S2, Comparison of human P4HA1 mRNA versus mouse P4HA1 mRNA expression in tumors. Supplemental Table S3, Correlation of P4HA1 and P4HA2 mRNA expression with receptor status
Supplementary Figure 2 from Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells
Authors: Chang Li-Yuan , Lin Yung-Chang , Mahalingam Jayashri , Huang Ching-Tai , Chen Ten-Wen , Kang Chiao-Wen , Peng Hui-Min , Chu Yu-Yi , Chiang Jy-Ming , Dutta Avijit , Day Yuan-Ji , Chen Tse-Ching , Yeh Chau-Ting , Lin Chun-Yen
Published: April 2023

PDF file - 78K
Supplementary Figure and Movie Legends from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

PDF file - 85K
Supplementary Figure 5 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: April 2023

PDF file - 657K, Depletion of 53BP1 rescues RAD51 assembly at DSB sites in BRCA1-depleted human cells
Supplementary Figures 2-6 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Authors: Laurent Julien , Hull Eveline Faes-van't , Touvrey Cedric , Kuonen François , Lan Qiang , Lorusso Girieca , Doucey Marie-Agnès , Ciarloni Laura , Imaizumi Natsuko , Alghisi Gian Carlo , Fagiani Ernesta , Zaman Khalil , Stupp Roger , Shibuya Masabumi , Delaloye Jean-François , Christofori Gerhard , Ruegg Curzio
Published: April 2023

Supplementary Figures 2-6 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Supplementary Table S1 from LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer
Authors: Permuth-Wey Jennifer , Kim Donghwa , Tsai Ya-Yu , Lin Hui-Yi , Chen Y. Ann , Barnholtz-Sloan Jill , Birrer Michael J. , Bloom Gregory , Chanock Stephen J. , Chen Zhihua , Cramer Daniel W. , Cunningham Julie M. , Dagne Getachew , Ebbert-Syfrett Judith , Fenstermacher David , Fridley Brooke L. , Garcia-Closas Montserrat , Gayther Simon A. , Ge William , Gentry-Maharaj Aleksandra , Gonzalez-Bosquet Jesus , Goode Ellen L. , Iversen Edwin , Jim Heather , Kong William , McLaughlin John , Menon Usha , Monteiro Alvaro N.A. , Narod Steven A. , Pharoah Paul D.P. , Phelan Catherine M. , Qu Xiaotao , Ramus Susan J. , Risch Harvey , Schildkraut Joellen M. , Song Honglin , Stockwell Heather , Sutphen Rebecca , Terry Kathryn L. , Tyrer Jonathan , Vierkant Robert A. , Wentzensen Nicolas , Lancaster Johnathan M. , Cheng Jin Q. , Sellers Thomas A.
Published: April 2023

Supplementary Table S1 from LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer
Supplementary Figure 1 from S-Glutathionylated Serine Proteinase Inhibitors as Plasma Biomarkers in Assessing Response to Redox-Modulating Drugs
Authors: Grek Christina L. , Townsend Danyelle M. , Uys Joachim D. , Manevich Yefim , Coker Woodrow J. , Pazoles Christopher J. , Tew Kenneth D.
Published: April 2023

PDF file - 2.1MB
Supplementary Table 1 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: April 2023

PDF file - 91K, Characteristics of patients from whom colon tissues were derived for immunostaining of beta-catenin and ALDH
Supplementary Figure 3 from Gliomagenesis Arising from Pten- and Ink4a/Arf-Deficient Neural Progenitor Cells Is Mediated by the p53-Fbxw7/Cdc4 Pathway, Which Controls c-Myc
Authors: Kim Hong Sug , Woolard Kevin , Lai Chen , Bauer Peter O. , Maric Dragan , Song Hua , Li Aiguo , Kotliarova Svetlana , Zhang Wei , Fine Howard A.
Published: April 2023

PDF file, 99K, c-Myc activity is decreased in Pten-/Ink4a/Arf-/-mNSCs.
Supplementary Table 2 from Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein–Coupled Receptor
Authors: Aguilar Berenice , Choi Inho , Choi Dongwon , Chung Hee Kyoung , Lee Sunju , Yoo Jaehyuk , Lee Yong Suk , Maeng Yong Sun , Lee Ha Neul , Park Eunkyung , Kim Kyu Eui , Kim Nam Yoon , Baik Jae Myung , Jung Jae U. , Koh Chester J. , Hong Young-Kwon
Published: April 2023

PDF file - 65K, Regulation of the expression of various nuclear receptors by KSHV in BECs
Supplementary Figure 1 from Genetic Ablation of Cav1 Differentially Affects Melanoma Tumor Growth and Metastasis in Mice: Role of Cav1 in Shh Heterotypic Signaling and Transendothelial Migration
Authors: Capozza Franco , Trimmer Casey , Castello-Cros Remedios , Katiyar Sanjay , Whitaker-Menezes Diana , Follenzi Antonia , Crosariol Marco , Llaverias Gemma , Sotgia Federica , Pestell Richard G. , Lisanti Michael P.
Published: April 2023

PDF file - 105K
Supplementary Methods, Figure Legends 1-3 from Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy
Authors: Maas Amanda L. , Carter Shirron L. , Wileyto E. Paul , Miller Joann , Yuan Min , Yu Guoqiang , Durham Amy C. , Busch Theresa M.
Published: April 2023

PDF file - 63K
Supplementary Figure 3 from Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy
Authors: Maas Amanda L. , Carter Shirron L. , Wileyto E. Paul , Miller Joann , Yuan Min , Yu Guoqiang , Durham Amy C. , Busch Theresa M.
Published: April 2023

PDF file - 2.6MB
Supplementary Figure 1 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: April 2023

PDF file - 1560K, Quantification of the flow cytometry profiles for the characterization of the four bone marrow cell populations sorted according to the expression of Nrp1 and Gr1. The results (shown as bar charts in the upper part of the figure and as a table in the bottom part) refer to four independent experiments; shown are the mean � s.d. The markers analyzed are the same as in the representative experiment shown in Figure 1D.
Supplementary Figure 2 from Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy
Authors: Maas Amanda L. , Carter Shirron L. , Wileyto E. Paul , Miller Joann , Yuan Min , Yu Guoqiang , Durham Amy C. , Busch Theresa M.
Published: April 2023

PDF file - 3.4MB
Supplementary Figure 1 from Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy
Authors: Maas Amanda L. , Carter Shirron L. , Wileyto E. Paul , Miller Joann , Yuan Min , Yu Guoqiang , Durham Amy C. , Busch Theresa M.
Published: April 2023

PDF file - 4.7MB
Supplementary Methods from The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by LKB1 Loss
Authors: Feng Yan , Wang Ye , Wang Zuoyun , Fang Zhaoyuan , Li Fei , Gao Yijun , Liu Hongyan , Xiao Tian , Li Fuming , Zhou Yang , Zhai Qiwei , Liu Xiaolong , Sun Yihua , Bardeesy Nabeel , Wong Kwok-kin , Chen Haiquan , Xiong Zhi-qi , Ji Hongbin
Published: April 2023

PDF file - 161K, Supplementary methods about plasmids and antibodies, immunofluorescence, soft agar assay and boyden chamber assay
Supplementary Figures S1-S6 from PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability
Authors: Shima Yutaka , Honma Yuki , Kitabayashi Issay
Published: April 2023

PDF file - 2380K, PML oligomerization is required for NB formation (S1); PML-RARa disrupts PML NBs (S2); PML-RARa 662-708 is required for the inhibition of PML NBs (S3); Interaction between PML IV and PML-RARa deletion and substitution mutants (S4); HIPK2 mRNA levels in the cells expressing HIPK2 and PML-RARa wild-type or point mutant at the third round of colonies (S5); Forskolin restores NBs in NB4 cells (S6)
Supplementary Figure Legends from PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability
Authors: Shima Yutaka , Honma Yuki , Kitabayashi Issay
Published: April 2023

PDF - 80K, Legend for Supplementary Figures S1-S6
Supplementary Figure 2 from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: April 2023

PDF file - 87K, TIC-specific aptamers preferentially bind TICs in comparison to non-TICs or U87MG cells.
Supplementary Figure Legend from Host Immune Defense Peptide LL-37 Activates Caspase-Independent Apoptosis and Suppresses Colon Cancer
Authors: Ren Shun X. , Cheng Alfred S.L. , To Ka F. , Tong Joanna H.M. , Li May S. , Shen Jin , Wong Clover C.M. , Zhang Lin , Chan Ruby L.Y. , Wang Xiao J. , Ng Simon S.M. , Chiu Lawrence C.M. , Marquez Victor E. , Gallo Richard L. , Chan Francis K.L. , Yu Jun , Sung Joseph J.Y. , Wu William K.K. , Cho Chi H.
Published: April 2023

PDF file - 58K
Supplementary Figure 1 from Host Immune Defense Peptide LL-37 Activates Caspase-Independent Apoptosis and Suppresses Colon Cancer
Authors: Ren Shun X. , Cheng Alfred S.L. , To Ka F. , Tong Joanna H.M. , Li May S. , Shen Jin , Wong Clover C.M. , Zhang Lin , Chan Ruby L.Y. , Wang Xiao J. , Ng Simon S.M. , Chiu Lawrence C.M. , Marquez Victor E. , Gallo Richard L. , Chan Francis K.L. , Yu Jun , Sung Joseph J.Y. , Wu William K.K. , Cho Chi H.
Published: April 2023

PDF file - 4.4MB, Figure S1 Apoptogenic function and mechanism of LL-37 in LoVo colon cancer cells
Supplementary Figure 3 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 75K, (A) MB49 cells were infected with 100 viral particles/cell with Ad5/3-CMV-mCD40L and Ad5/3-Luc1 and Annexin-V was assessed 24 hours post-infection by flow cytometry. (B) Replication of Ad5/3-CMV-mCD40L and Ad5/3-Luc1 over time in MB49 cell line. Cell monolayers were infected at doses specified ranging from 101 to 108 viral particles and assays were stopped at different time points (days 2, 3, 4 and 8). Cell viability was measured and expressed overtime. (C) MB49 cells were infected with 100 viral particles and samples were collected at 0, 24, 48 and 72 hours post infection. Quantitative PCR was performed for E4 sequence and values were normalized to mouse beta-actin gene.
Supplementary Figures 1 - 5 from Pivotal Role of the Lipid Raft SK3–Orai1 Complex in Human Cancer Cell Migration and Bone Metastases
Authors: Chantôme Aurélie , Potier-Cartereau Marie , Clarysse Lucie , Fromont Gaëlle , Marionneau-Lambot Séverine , Guéguinou Maxime , Pagès Jean-Christophe , Collin Christine , Oullier Thibauld , Girault Alban , Arbion Flavie , Haelters Jean-Pierre , Jaffrès Paul-Alain , Pinault Michelle , Besson Pierre , Joulin Virginie , Bougnoux Philippe , Vandier Christophe
Published: April 2023

PDF file - 579K, S1. Validation of the MDA-MB-435s cell system expressing luciferase gene and expressing or not KCNN3 gene. S2. SK3 knockdown reduced the development of metastases in cancer cell xenograft models. A) SK3 knockdown reduced the metastatic score in cancer cell xenograft model. S3.Role of Orai1 in the constitutive SK3-dependent calcium entry and SK3+ cell migration. S4. Effect of Ohmline on Orai1 and SK3 expression and on constitutive calcium entry. S5. SK3 protein was expressed in smooth muscle cells of urinary bladder detrusor and myometrium and in primary tumour form mice grafted with SK3+ cells 16 weeks post grafted.
Supplementary Figures 1 - 10 from Cetuximab Response of Lung Cancer–Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization
Authors: Cho Jeonghee , Chen Liang , Sangji Naveen , Okabe Takafumi , Yonesaka Kimio , Francis Joshua M. , Flavin Richard J. , Johnson William , Kwon Jihyun , Yu Soyoung , Greulich Heidi , Johnson Bruce E. , Eck Michael J. , Jänne Pasi A. , Wong Kwok-Kin , Meyerson Matthew
Published: April 2023

PDF file - 303K, L704N or I941R cis mutation disrupts constitutive dimerization of mutant EGFR (S1); Tyrosine-phosphorylation is abrogated on L704N or I941R compound mutants of dimerization-dependent mutants (S2); Wild-type EGFR, but not Ex20Ins mutant are dependent on asymmetric dimerization for oncogenic transformation (S3); Tyrosine-phosphorylation on dimerization-independent mutants is significantly impaired by introduction of receiver-impairing or activator-impairing mutation (S4); Cell surface expression levels of various EGFR mutants in NIH-3T3 cells (S5); Activities of receiver monomers and activator monomers of wild-type EGFR (S6); Cell surface expression of mutant EGFR in stable cell lines (S7); Differential pharmacological effects of gefitinib and cetuximab against distinct mutant EGFR (S8); Generation and characterization of bitransgenic mice with inducible expression of EGFR Ex20Ins in lung compartments (S9); Cetuximab downregulates tyrosine phosphorylation on mutant EGFR in mouse tumors (S10).
Supplementary Table 1 from GDNF–RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors
Authors: Morandi Andrea , Martin Lesley-Ann , Gao Qiong , Pancholi Sunil , Mackay Alan , Robertson David , Zvelebil Marketa , Dowsett Mitch , Plaza-Menacho Ivan , Isacke Clare M.
Published: April 2023

XLSX file - 1167K, Gene Set Expression Analysis (GSEA) performed using default values for all the parameters. Also includes GDNF-RGS gene list and GO Analysis.
Supplementary Figure Legend from Cetuximab Response of Lung Cancer–Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization
Authors: Cho Jeonghee , Chen Liang , Sangji Naveen , Okabe Takafumi , Yonesaka Kimio , Francis Joshua M. , Flavin Richard J. , Johnson William , Kwon Jihyun , Yu Soyoung , Greulich Heidi , Johnson Bruce E. , Eck Michael J. , Jänne Pasi A. , Wong Kwok-Kin , Meyerson Matthew
Published: April 2023

PDF file - 164K
Supplementary Figure 3 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 244K, Ortholog gene of MUS81 is not registered in the chicken database.
Supplementary Figure 1 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 311K, Sequence alignment among human, mouse, and chicken Xpf.
Supplementary Figure 5 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 86K, ssGSEA identifies gene sets that correlate with radiation resistance (left) and sensitivity (right). Top 15 gene sets are listed.
Supplementary Figure 1 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 282K, Clonogenic survival following exposure to �-radiation.
Supplementary Figure 2 from Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
Authors: Licciulli Silvia , Avila Jacqueline L. , Hanlon Linda , Troutman Scott , Cesaroni Matteo , Kota Smitha , Keith Brian , Simon M. Celeste , Puré Ellen , Radtke Fred , Capobianco Anthony J. , Kissil Joseph L.
Published: April 2023

PDF file, 8785K, Notch1 ablation does not induce DNA damage in vitro.
Supplementary Figure 2 from Loss of ARF Sensitizes Transgenic BRAFV600E Mice to UV-Induced Melanoma via Suppression of XPC
Authors: Luo Chi , Sheng Jinghao , Hu Miaofen G. , Haluska Frank G. , Cui Rutao , Xu Zhengping , Tsichlis Philip N. , Hu Guo-Fu , Hinds Philip W.
Published: April 2023

PDF file - 343K, p53 function in BRAFV600E/ARF-/- murine melanoma cells.
Supplementary Figure Legends from MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells
Authors: Stroopinsky Dina , Rosenblatt Jacalyn , Ito Keisuke , Mills Heidi , Yin Li , Rajabi Hasan , Vasir Baldev , Kufe Turner , Luptakova Katarina , Arnason Jon , Nardella Caterina , Levine James D. , Joyce Robin M. , Galinsky Ilene , Reiter Yoram , Stone Richard M. , Pandolfi Pier Paolo , Kufe Donald , Avigan David
Published: April 2023

PDF file, 22K.
Supplementary Figure 2 from MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells
Authors: Stroopinsky Dina , Rosenblatt Jacalyn , Ito Keisuke , Mills Heidi , Yin Li , Rajabi Hasan , Vasir Baldev , Kufe Turner , Luptakova Katarina , Arnason Jon , Nardella Caterina , Levine James D. , Joyce Robin M. , Galinsky Ilene , Reiter Yoram , Stone Richard M. , Pandolfi Pier Paolo , Kufe Donald , Avigan David
Published: April 2023

PDF file, 3806K, CD34-/lineage-cells from patient #25 were sorted into MUC1high and MUC1low populations.
Supplementary Figure Legend from Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
Authors: Zhang Yaqing , Yan Wei , Collins Meredith A. , Bednar Filip , Rakshit Sabita , Zetter Bruce R. , Stanger Ben Z. , Chung Ivy , Rhim Andrew D. , di Magliano Marina Pasca
Published: April 2023

PDF file - 111K
Supplementary Text from Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment
Authors: Le Mercier Isabelle , Poujol Dominique , Sanlaville Amélien , Sisirak Vanja , Gobert Michael , Durand Isabelle , Dubois Bertrand , Treilleux Isabelle , Marvel Jacqueline , Vlach Jaromir , Blay Jean-Yves , Bendriss-Vermare Nathalie , Caux Christophe , Puisieux Isabelle , Goutagny Nadège
Published: April 2023

Supplementary Text - PDF file 132K, Supplementary Material and methods, and Supplementary figure legends
Supplementary Table 9 from MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity
Authors: Wasylishen Amanda R. , Chan-Seng-Yue Michelle , Bros Christina , Dingar Dharmendra , Tu William B. , Kalkat Manpreet , Chan Pak-Kei , Mullen Peter J. , Huang Ling , Meyer Natalie , Raught Brian , Boutros Paul C. , Penn Linda Z.
Published: April 2023

XLS file, 98K, GO analysis of common gene expression changes.
Supplementary Table 5 from MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity
Authors: Wasylishen Amanda R. , Chan-Seng-Yue Michelle , Bros Christina , Dingar Dharmendra , Tu William B. , Kalkat Manpreet , Chan Pak-Kei , Mullen Peter J. , Huang Ling , Meyer Natalie , Raught Brian , Boutros Paul C. , Penn Linda Z.
Published: April 2023

XLSX file, 14K, Gene expression changes common to wild type MYC and all phosphorylation mutants (112 genes).
Supplementary Figure S4 from Peroxiredoxin-2 Represses Melanoma Metastasis by Increasing E-Cadherin/β-Catenin Complexes in Adherens Junctions
Authors: Lee Doo Jae , Kang Dong Hoon , Choi Mina , Choi Yang Ji , Lee Joo Young , Park Joo Hyun , Park Yoon Jung , Lee Kyung Wha , Kang Sang Won
Published: April 2023

Supplementary Figure S4 -�PDF file 1782K, The E-cadherin expression and �-catenin retention in plasma membrane is controlled independently via ERK and Src pathways
Supplementary Figure Legends from Peroxiredoxin-2 Represses Melanoma Metastasis by Increasing E-Cadherin/β-Catenin Complexes in Adherens Junctions
Authors: Lee Doo Jae , Kang Dong Hoon , Choi Mina , Choi Yang Ji , Lee Joo Young , Park Joo Hyun , Park Yoon Jung , Lee Kyung Wha , Kang Sang Won
Published: April 2023

Supplementary Figure Legends�- PDF file 151K, Legend for Supplementary Figures S1-S5
Supplementary Table 1 from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

PDF file - 57K, Accession numbers and amplified context sequences of the genes analyzed by quantitative RT-PCR.
Supplementary Movie 5 from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

AVI file - 4312K, Time-lapse video-recording of a representative JVM3 cell expressing GFP-CCR7 distribution and migrating in a CCL19 gradient (source of CCL19 towards the bottom).
Supplementary Movie 4 from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

AVI file - 1553K, Time-lapse video-recording of a representative JVM3 cell expressing GFP-actin and migrating in a CCL19 gradient (source of CCL19 towards the bottom).
Supplementary Table 1 from Lysyl Oxidase Plays a Critical Role in Endothelial Cell Stimulation to Drive Tumor Angiogenesis
Authors: Baker Ann-Marie , Bird Demelza , Welti Jonathan C. , Gourlaouen Morgane , Lang Georgina , Murray Graeme I. , Reynolds Andrew R. , Cox Thomas R. , Erler Janine T.
Published: April 2023

PDF file - 54K, Distribution of CD31 and LOX immunoreactivity in a tissue microarray of patient samples
Supplementary Figure 2 from Dose-Dense Chemotherapy Improves Mechanisms of Antitumor Immune Response
Authors: Chang Chih-Long , Hsu Yun-Ting , Wu Chao-Chih , Lai Yan-Zen , Wang Connie , Yang Yuh-Cheng , Wu T.-C. , Hung Chien-Fu
Published: April 2023

PDF file - 405K, Supplemental figure 2 demonstrates superior efficacy of dose dense treatment compared to maximum tolerated dose treatment in a platinum-resistant tumor model.
Supplementary Figures from Tumor Cells Upregulate Normoxic HIF-1α in Response to Doxorubicin
Authors: Cao Yiting , Eble Joseph M. , Moon Ejung , Yuan Hong , Weitzel Douglas H. , Landon Chelsea D. , Yu-Chih Nien Charleen , Hanna Gabi , Rich Jeremy N. , Provenzale James M. , Dewhirst Mark W.
Published: April 2023

PDF file, 257K, Western blot: doxorubicin-induced normoxic HIF-1� expression was compared to a positive control of HIF-1� induced by hypoxia (S1); Hoechst 33342 labeling: comparison of perfused tumor fraction in 4T1ODD-luc tumors on days 0, 1, 4, 7, and 16 post-treatment (n = 5, mean � SE). P > 0.05. Student t test (S2); Western blot: increasing concentration of doxorubicin led to higher HIF-1� expression 48 hours post-treatment (S3); WST-1 cell viability assay at 24, 48, and 72 hours post-treatment (S4), Western blot: the expressions of JAK2 and phosphorylated JAK2 (Tyr1007/1008) 48 hours post-treatment (S5); Quantification of iNOS band density which is normalized to loading control in Fig. 5D (S6); Comparison of TAM-specific marker CD68 fraction in 4T1ODD-luc tumors on days 0, 1, 4, 7, and 16 post-treatment (n = 5, mean � SE). P > 0.05, Student t test (S7).
Supplementary Figures 1-8 from EGFR/JIP-4/JNK2 Signaling Attenuates Cetuximab-Mediated Radiosensitization of Squamous Cell Carcinoma Cells
Authors: Eke Iris , Schneider Lydia , Förster Claudia , Zips Daniel , Kunz-Schughart Leoni A. , Cordes Nils
Published: April 2023

PDF file - 621K, Supplementary Figure S1. Treatment with Cetuximab inhibits EGF-mediated EGFR phosphorylation under 2D and 3D cell culture conditions in a cell line-dependent manner. Supplementary Figure S2. Induction of Cetuximab-mediated apoptosis in non-irradiated and irradiated 3D grown SCC cells. Supplementary Figure S3. EGFR inhibition with Cetuximab results in minor Caspase 3 cleavage. Supplementary Figure S4. Treatment with Cetuximab modulates tyrosine and serine protein phosphorylation. Supplementary Figure S5. JNK inhibition using siRNA or pharmacological inhibitor (SP600125) reduces cell survival of SCC cells. Supplementary Figure S6. JNK inhibition impairs Cetuximab-mediated c-Jun S63 phosphorylation. Supplementary Figure S7. JNK2 knockdown sensitizes UTSCC5 cells to Cetuximab-mediated radiosensitization. Supplementary Figure S8. EGFR and JIP-4 co-precipitate in untreated FaDu 3D cell cultures
Supplementary Figure 1 from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 30K, PC3-MM2/Trop-2-GFP disseminated in liver parenchyma.
Supplementary Methods and Tables from HOXB13 Mediates Tamoxifen Resistance and Invasiveness in Human Breast Cancer by Suppressing ERα and Inducing IL-6 Expression
Authors: Shah Nilay , Jin Kideok , Cruz Leigh-Ann , Park Sunju , Sadik Helen , Cho Soonweng , Goswami Chirayu Pankaj , Nakshatri Harikrishna , Gupta Rajnish , Chang Howard Y. , Zhang Zhe , Cimino-Mathews Ashley , Cope Leslie , Umbricht Christopher , Sukumar Saraswati
Published: April 2023

PDF file, 154K, Table S1: Primers used for PCR ; Table S2. Antibodies used for Western Blot ; Table S3 Treatment comparisons of tumor volumes at selected time points. ; Table S4: Treatment comparisons of tumor volumes at selected time points -MCF7-HOXB13 cell line, SC xenografts ; Table S5: Treatment comparisons of tumor volumes at selected time points MCF7-LPCX cell line, MFP xenografts ; Table S6. Treatment comparisons of tumor volumes at selected time points-MCF7-HOXB13 cell line, MFP xenografts.
Supplementary Table 1 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

XLSX file - 713K, Excel sheet containing additional data for main Figure 4.
Supplementary Methods from ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF-κB and Drives Prostate Cancer Progression
Authors: Longoni Nicole , Sarti Manuela , Albino Domenico , Civenni Gianluca , Malek Anastasia , Ortelli Erica , Pinton Sandra , Mello-Grand Maurizia , Ostano Paola , D'Ambrosio Gioacchino , Sessa Fausto , Garcia-Escudero Ramon , Thalmann George N. , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: April 2023

PDF file - 94K, Supplementary materials contain detailed description of the bioinformatic approaches such as Functional Annotation, Transcription factor interactome analysis, Gene Set Enrichment analysis and Survival analysis.
Supplementary Figure 4 from Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924
Authors: Blank Jonathan L. , Liu Xiaozhen J. , Cosmopoulos Katherine , Bouck David C. , Garcia Khristofer , Bernard Hugues , Tayber Olga , Hather Greg , Liu Ray , Narayanan Usha , Milhollen Michael A. , Lightcap Eric S.
Published: April 2023

PDF file - 162K, Genes Selected Based upon Extreme BI Scores are More Likely to Have Extreme Deconvoluted Oligo Scores than Those Selected Based upon Biology or Randomly
Supplementary Experimental Procedures from FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Authors: Liu Rui , Li Jingyi , Xie Ke , Zhang Tao , Lei Yunlong , Chen Yi , Zhang Lu , Huang Kai , Wang Kui , Wu Hong , Wu Min , Nice Edouard C. , Huang Canhua , Wei Yuquan
Published: April 2023

PDF file, 165K.
Supplementary Table 3 from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
Authors: Heitzer Ellen , Auer Martina , Gasch Christin , Pichler Martin , Ulz Peter , Hoffmann Eva Maria , Lax Sigurd , Waldispuehl-Geigl Julie , Mauermann Oliver , Lackner Carolin , Höfler Gerald , Eisner Florian , Sill Heinz , Samonigg Hellmut , Pantel Klaus , Riethdorf Sabine , Bauernhofer Thomas , Geigl Jochen B. , Speicher Michael R.
Published: April 2023

PDF file - 92K, Identification of mutations in cancer candidate (CAN) genes in patient samples using next-generation sequencing. Mutations that are shared between primary tumor and/or metastasis and/or CTCs are highlighted in bold.
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: April 2023

Supplementary Figure Legends
Supplementary Materials and Methods from Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling
Authors: Li Zhiping , Chen Ke , Jiao Xuanmao , Wang Chenguang , Willmarth Nicole E. , Casimiro Mathew C. , Li Weihua , Ju Xiaoming , Kim Sung Hoon , Lisanti Michael P. , Katzenellenbogen John A. , Pestell Richard G.
Published: April 2023

PDF file - 33KB
Supplementary Figure 1 from Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling
Authors: Li Zhiping , Chen Ke , Jiao Xuanmao , Wang Chenguang , Willmarth Nicole E. , Casimiro Mathew C. , Li Weihua , Ju Xiaoming , Kim Sung Hoon , Lisanti Michael P. , Katzenellenbogen John A. , Pestell Richard G.
Published: April 2023

PDF file - 15KB, Endogenous cyclin D1 mediates both E2 and EDC-induced yH2AX in MCF-7 cells.
Supplementary Video 5 from Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach
Authors: Kim Eunjung , Rebecca Vito , Fedorenko Inna V. , Messina Jane L. , Mathew Rahel , Maria-Engler Silvya S. , Basanta David , Smalley Keiran S.M. , Anderson Alexander R.A.
Published: April 2023

MOV file - 7443K, This video shows the spatio-temporal evolution of vSkin that produced Figure 6A (normal melanocytes and highly senescent fibroblasts).
Supplementary Figure S2 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: April 2023

Supplementary Figure S2 PDF file - 212K, Effects of PP242 on suppression of mTORC (A) and Akt (B) signaling
Supplementary Figure 1 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: April 2023

PDF file - 721KB, Imaging of tumor cell proliferation using 18FFLT PET in PC9 tumors.
Supplementary Video 2 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

AVI file - 1261KB, Representative 3D RENDERING HFK EETE.
Supplementary Table 2 from Mixed Lineage Kinase MLK4 Is Activated in Colorectal Cancers Where It Synergistically Cooperates with Activated RAS Signaling in Driving Tumorigenesis
Authors: Martini Miriam , Russo Mariangela , Lamba Simona , Vitiello Elisa , Crowley Emily Hannah , Sassi Francesco , Romanelli Davide , Frattini Milo , Marchetti Antonio , Bardelli Alberto
Published: April 2023

PDF file - 30K, Primers used for PCR amplification and sequencing of the MLK4 exons in tumor samples.
Supplementary Video 1 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

AVI file - 1575KB, Representative endogenous TPEF OPTICAL STACK HFK EETE.
Supplementary Figure Legend from Mixed Lineage Kinase MLK4 Is Activated in Colorectal Cancers Where It Synergistically Cooperates with Activated RAS Signaling in Driving Tumorigenesis
Authors: Martini Miriam , Russo Mariangela , Lamba Simona , Vitiello Elisa , Crowley Emily Hannah , Sassi Francesco , Romanelli Davide , Frattini Milo , Marchetti Antonio , Bardelli Alberto
Published: April 2023

PDF file - 98K
Supplementary Figure 4 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

PDF file - 516KB, TPEF images and quantitative data from cells exposed to KSFM, Low Glu (low glucose), No Glu (no glucose), and Low Oxy (low O2) media.
Supplementary Figure 2 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

PDF file - 139KB, Representative histological staining of cytokeratin 14 (K14), cytokeratin 10 (K10), involucrin (INV) and loricrin (LOR) for each type of EETE.
Supplementary Figure 1 from Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
Authors: Breitbach Caroline J. , Arulanandam Rozanne , De Silva Naomi , Thorne Steve H. , Patt Richard , Daneshmand Manijeh , Moon Anne , Ilkow Carolina , Burke James , Hwang Tae-Ho , Heo Jeong , Cho Mong , Chen Hannah , Angarita Fernando A. , Addison Christina , McCart J. Andrea , Bell John C. , Kirn David H.
Published: April 2023

Supplementary Figure 1 PDF file - 74K, VEGF- and FGF-2 stimulate vaccinia replication
Supplementary Table 1 from Loss of the Polycomb Mark from Bivalent Promoters Leads to Activation of Cancer-Promoting Genes in Colorectal Tumors
Authors: Hahn Maria A. , Li Arthur X. , Wu Xiwei , Yang Richard , Drew David A. , Rosenberg Daniel W. , Pfeifer Gerd P.
Published: April 2023

XLS file - 4089KB, Whole genome (genes) annotation for bivalent state in colon mucosa and gene activation in colorectal cancer.
Supplementary Figure 3 from Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Authors: Estrella Veronica , Chen Tingan , Lloyd Mark , Wojtkowiak Jonathan , Cornnell Heather H. , Ibrahim-Hashim Arig , Bailey Kate , Balagurunathan Yoganand , Rothberg Jennifer M. , Sloane Bonnie F. , Johnson Joseph , Gatenby Robert A. , Gillies Robert J.
Published: April 2023

PDF file - 46K, Figure S3: Growth of MDAmb231 tumor within the dorsal window chamber. Mean growth of MDAmb23/GFP tumors within the dorsal window chamber. Cells were embedded in a 0.8 mg/mL collagen type 1 matrix followed by inoculation into the window chamber. Tumor area was measured at days 2, 3, and 16 by counting the number of pixels. Tumor area measured by fluorescence pixel number obtained using Image-Pro Plus 6.2.
Supplementary Tables 1 - 2 from SRC Signaling Is Crucial in the Growth of Synovial Sarcoma Cells
Authors: Michels Sebastian , Trautmann Marcel , Sievers Elisabeth , Kindler Dagmar , Huss Sebastian , Renner Marcus , Friedrichs Nicolaus , Kirfel Jutta , Steiner Susanne , Endl Elmar , Wurst Peter , Heukamp Lukas , Penzel Roland , Larsson Olle , Kawai Akira , Tanaka Shinya , Sonobe Hiroshi , Schirmacher Peter , Mechtersheimer Gunhild , Wardelmann Eva , Büttner Reinhard , Hartmann Wolfgang
Published: April 2023

PDF file - 57K, Densitometric analysis of the top five phosphorylated kinases as found in phospho kinase arrays in 1273/99 and HS-SY-II synovial sarcoma cells. Flow cytometric analysis of three synovial sarcoma cell lines treated with different doses of dasatinib for 48 hours.
Supplementary Figure 2 from Inherited Variation in miR-290 Expression Suppresses Breast Cancer Progression by Targeting the Metastasis Susceptibility Gene Arid4b
Authors: Goldberger Natalie , Walker Renard C. , Kim Chang Hee , Winter Scott , Hunter Kent W.
Published: April 2023

PDF file - 112K, Schematic of miR-290 structure generated by MFold.
Supplementary Table 1 from Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Authors: Lee Genee Y. , Haverty Peter M. , Li Li , Kljavin Noelyn M. , Bourgon Richard , Lee James , Stern Howard , Modrusan Zora , Seshagiri Somasekar , Zhang Zemin , Davis David , Stokoe David , Settleman Jeffrey , de Sauvage Frederic J. , Neve Richard M.
Published: April 2023

XLSX file - 37K, Details of the tumour samples use in the article.
Supplementary Table 3 from Notch3 Pathway Alterations in Ovarian Cancer
Authors: Hu Wei , Liu Tao , Ivan Cristina , Sun Yunjie , Huang Jie , Mangala Lingegowda S. , Miyake Takahito , Dalton Heather J. , Pradeep Sunila , Rupaimoole Rajesh , Previs Rebecca A. , Han Hee Dong , Bottsford-Miller Justin , Zand Behrouz , Kang Yu , Pecot Chad V. , Nick Alpa M. , Wu Sherry Y. , Lee Ju-Seog , Sehgal Vasudha , Ram Prahlad , Liu Jinsong , Tucker Susan L. , Lopez-Berestein Gabriel , Baggerly Keith A. , Coleman Robert L. , Sood Anil K.
Published: April 2023

PDF file - 55K, Correlation between key transcription factors and Notch3 overexpression.
Supplementary Figure 3 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: April 2023

PDF file - 72KB, Positive controls for transfection assays.
Supplementary Table 9 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 33K, Set of 304 genes differentially expressed between Gleason 3+4 pattern and Gleason 4+3 pattern patients based on DEseq analysis (p < 0.05).
Supplementary Table 4 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 9K, Prediction Model based on Clinical Variables alone, namely, tGleason score, Log(prePSA + ), pStage, Surgical Margin Status, and Age.
Supplementary Figure 1 from Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways
Authors: Verhaegh Wim , van Ooijen Henk , Inda Márcia A. , Hatzis Pantelis , Versteeg Rogier , Smid Marcel , Martens John , Foekens John , van de Wiel Paul , Clevers Hans , van de Stolpe Anja
Published: April 2023

PDF file - 174KB, Variation of predicted ER pathway activity for sample replicates.
Supplementary Figure 3 from Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
Authors: Berger Penny L. , Frank Sander B. , Schulz Veronique V. , Nollet Eric A. , Edick Mathew J. , Holly Brittany , Chang Ting-Tung A. , Hostetter Galen , Kim Suwon , Miranti Cindy K.
Published: April 2023

PDF file - 134KB, Constitutive Myc expression leads to cell death after differentiation.
Supplementary Figure 3 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 2139K, Effects of anti-JAM-C antibody binding on apoptosis of human B cells
Supplementary Figure 2 from Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
Authors: Berger Penny L. , Frank Sander B. , Schulz Veronique V. , Nollet Eric A. , Edick Mathew J. , Holly Brittany , Chang Ting-Tung A. , Hostetter Galen , Kim Suwon , Miranti Cindy K.
Published: April 2023

PDF file - 123KB, K14 loss is coincidental with integrin a6 loss.
Supplementary Figure 4 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: April 2023

PDF file - 126K, Dual inhibition of Chk1 and Wee1 significantly impairs tumor growth in vivo. Mice were treated with either 30 mg/kg of single agent MK-1775 (targeting Wee1), single-agent MK-8776 (targeting Chk1) or simultaneous MK-1775 and MK-8776. Mixed linear effects model was used to calculate the rate of tumor growth in each condition, and demonstrated that dual inhibition was efficacious in both SKNAS and NB1643 xenograft models. Mice harboring NB1643 xenografts were treated for 48h, tumors were resected and target engagement was validated by western blot analysis
Supplementary Figure 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: April 2023

PDF file - 133K, Expression and activity of Wee1 is prevalent in neuroblastoma. (A) A secondary panel of neuroblastoma cell lines demonstrated Wee1 expression and activation (evidenced by phospho-Ser642) by western blot. Cdc2 activity was observed in all neuroblastoma lines. (B) A variety of adult cancer lines were tested for Wee1 phosphorylation, and were generally much lower than that seen in neuroblastoma (far right lanes)
Supplementary Movie 2 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: April 2023

MOV file - 3841K, Movie before (left) and after (right) EB3-GFP comet detection (blue dots) with plusTipTracker, acquisition of 125 frames, 1.25 Hz, 12.5 fold accelerated.
Supplementary Figure S2 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: April 2023

Supplementary Figure S2 PDF file - 39K, A standard 51Cr release assay was performed using K562, U937 or KL-1 as target cell lines, as described in the "Materials and Methods" section. These targets were labeled with 51Cr (Perkin Elmer, Boston, MA, USA) at 50 ��Ci/5 �~ 105 cells and incubated at 5 �~ 103 cells/well with resting human NK cells at E:T ratios of 30:1, 10:1 and 3:1. Percent specific lysis was calculated as follows: 100 �~ (experimental release-spontaneous release)/(maximum release-spontaneous release)
Supplementary Figure 5 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: April 2023

PDF file - 44K, Staining for γH2AX (brown) in sections of the intestine from a CK1α-deficient mouse
Supplementary Table from RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Authors: Huan Jianya , Hornick Noah I. , Shurtleff Matthew J. , Skinner Amy M. , Goloviznina Natalya A. , Roberts Charles T. , Kurre Peter
Published: April 2023

PDF file - 143K, All primers were used in semi-quantitative PCR
Supplementary Figure 3 from RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Authors: Huan Jianya , Hornick Noah I. , Shurtleff Matthew J. , Skinner Amy M. , Goloviznina Natalya A. , Roberts Charles T. , Kurre Peter
Published: April 2023

PDF file - 156K, AML exosomes can alter gene expression and protein secretion
Supplementary Figure 2 from RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Authors: Huan Jianya , Hornick Noah I. , Shurtleff Matthew J. , Skinner Amy M. , Goloviznina Natalya A. , Roberts Charles T. , Kurre Peter
Published: April 2023

PDF file - 456K, Co-culture of AML cells with stromal cell can alter gene expression and protein secretion