bluuebunny/crossref_metadata_2025 huggingface dataset:
COMPARISON OF RP-HPLC AND UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF HALOPERIDOL IN PURE AND PHARMACEUTICAL FORMULATION
Authors: Jain AK , Dubey BK , Basedia D , Dhakar S , Ahirwar M , Jain P
Published: November 2018

An accurate, precise, sensitive and reproducible High-performance liquid chromatographic (HPLC) and UV spectrophotometric methods were developed and validated for the quantitative determination of haloperidol (HPD) in bulk drug and pharmaceutical formulation. Different analytical performance parameters such as linearity, precision, accuracy, specificity, limit of detection (LOD) and limit of quantification (LOQ) were determined according to International Conference on Harmonization ICH Q2B guidelines. The RP-HPLC method was developed by the isocratic technique on a reversed-phase Thermo C18 (250 × 4.6 mm, 5µm) column with mobile phase consisting of Methanol: Acetonitrile (50:50v/v) at flow rate of 1.0 ml/min. The retention time for HPD was 2.238±0.3min. The UV spectrophotometric determinations were performed at 244 nm using 80% methanol as a solvent. The linearity range for HPD was 5-25 μg/ml for both HPLC and UV method. The linearity of the calibration curves for each analyte in the desired concentration range was good (r2 >0.999) by both the HPLC and UV methods. The method showed good reproducibility and recovery with percent relative standard deviation less than 2%. Moreover, the accuracy and precision obtained with HPLC co-related well with the UV method which implied that UV spectroscopy can be a cheap, reliable and less time consuming alternative for chromatographic analysis. The proposed methods are highly sensitive, precise and accurate and hence successfully applied for determining the assay and in vitro dissolution of a marketed formulation.

Keywords: HPLC, UV Spectrophotometry, Haloperidol, Pharmaceutical formulation, Method validation, Quantitative analysis
Study on Fish Fauna Diversity of Bhusara maun under Muzaaffarpur district of Bihar
Authors: Kumari Nishi , Pathak Ravindra Nath
Published: November 2018

The present study has been carried from Bhusara maun under Muzaaffarpur district of Bihar”. Fish diversity on this lentic water body has been studied in detail with its food value and commercial status. Twenty eight Fish species of fishes were recorded, which belonged to 20 genera and 14 families. A classified list of fishes has been given. The Indian major carps and few fresh species are commercially important groups in the Bhusara maun

Keywords: Fish species, diversity, food value. Commercially important.
Study on the Diversity and seasonal variation of zooplankton in Bhusara maun under Muzaffarpur, Bihar
Authors: Kumari Nishi , Pathak Ravindra Nath
Published: November 2018

Diversity of zooplankton in the Bhusara maun was studied during March 2010- Feb 2011. The population of zooplankton consisted of rotifers copepods and cladocerans. Total number of zooplankton recorded were 2335 per litre of which rotifers were 1461 (62.56%), cladocerans 226 (9.67%) and copepods 608 (27.75%). All the dominant groups of zooplankton present throughout the year. Diversity analysis showed that rotifers had 11 species cladoccrans four and copepode four species. High number of zooplankton were recorded in winter season. While low number was recorded in monsoon season.

Keyword: Zooplankton, Bimodal distribution, Diversity richness
THERAPEUTIC MICROEMULSION OF CURCUMIN FOR THE MANAGEMENT OF OSTEOARTHRITIS
Authors: Sharma Shreyasi , Ganju Eisha , Upmanyu Neeraj , Jain Prabhat
Published: November 2018

Curcumin (diferuloylmethane) is a natural polyphenolic compound with potent anti-inflammatory, anticancer and antioxidant activities. However, its bioavailability is low as it is poorly absorbed in the gastrointestinal tract. Microemulsions offer the potential to improve the solubility and bioavailability of bioactive compounds; the present work investigated the topical delivery potential of microemulsion gel loaded with curcumas. Curcumin microemulsion was prepared by spontaneous emul­sification method using oil (Oleic acid), surfactant:cosurfactant (Smix) (Ethanol and Tween 80, Span 80 and n Butanol) and water. The optimized formulations of microemulsions were subjected to thermodynamic stability tests. After stability study, stable formulation was characterized for droplet size, pH determination, centrifugation, % drug content in microemulsion, zeta potential and vesicle size measurement and then microemulsion gel were prepared and characterized for spreadability, measurement of viscosity, drug content, In-vitro diffusion, in-vitro release data. Tween 80, Span 80 was selected as surfactant, ethanol, n Butanol as co surfactant and Oleic acid as oil component based on solubility study. The optimized formulation contained Curcumin (10 mg). The in vitro drug release from curcumin microemulsion gel was found to be considerably higher in comparison to that of the pure drug. The in-vitro diffusion of microemulsion gel was significantly good. Based on this study, it can be concluded the solubility and permeability of curcumin can be increased by formulating into microemulsion gel.

Keyword: Curcumin, Microemulsion, In-vitro diffusion, Spreadability, Zeta potential, Stability, span 40
Enhancement of solubility & dissolution rate of Nifedipine by using Novel Solubilizer sepitrap 80 & Sepitrap 4000
Authors: Jagtap Rajesh Shankar , Doijad Rajendra , Mohite Shrinivas
Published: November 2018

The enhancement in solubility and dissolution rate of BCS class-II drug Nifedipine was achieved by simple physical mixture with sepitrap 80 & sepitrap 4000 in 1:1 & 1:2 proportion. The saturation solubility studies shows 263 % & 368 % increase in the solubility in physical mixture of Nifedipine with sepitrap 80 & sepitrap 4000 respectively. The physicochemical properties of pure Nifedipine compared to their physical mixtures with sepitrap 80 & sepitrap 4000 were determined using FTIR, DSC & PXRD. The FTIR and DSC studies shows no any interaction in Nifedipine and sepitrap, the marked broadening and distinct reduction in intensity with shifting of drug endotherm was displayed physical mixture with sepitrap demonstrate positive effect. The PXRD diffractograms shows distinctive peaks but reduction in peak intensity in terms of counts indicating conversion of drug in amorphous forms. The surface morphology of the prepared physical mixture was examined by SEM which indicating no significant change in its surface morphology due to no use any solvent during the preparation of physical mixture . Photostability studies shows that rate of photo degradation is very slow in Physical mixture with sepitrap as compared to pure Nifedipine. Dissolution studies in SGF & SIF shows that significant enhancement by use of novel solubilizer sepitrap 80 as well as sepitrap 4000 in 1:2 proportions. The physical mixture containing sepitrap 4000 was found stable as there was no any significant change in appearance and drug dissolution after three month stability studies.
Potential Drug-Drug Interactionsamong Adult Patients Admitted to MedicalWards at a Tertiary Teaching Hospital inEthiopia
Authors: Kibrom Samson , Tilahun Zelalem , Huluka Solomon Assefa
Published: November 2018

Abstract

Introduction: A Drug-drug interaction (DDI) is a decrease or increase in the pharmacological or clinical response to the administration of two or more drugs that are different from the anticipated response they initiate when individually administered.

Objectives: To assess the prevalence and factors associated with potential DDIs among adult inpatients admitted to the medical wards of a tertiary teaching Hospital in Ethiopia.

Methods: A retrospective cross-sectional study design was employed on adult patients who were admitted to the medical ward in one year period. A total of 384patients’ medical records were checked for a possible DDI using Micromedex DrugReax® drug interaction database and analyzed consecutively using SPSS version 20.0.

Results: Among 384 adult patients enrolled in the study, 209 (54.4%) of them had medications with at least one potential DDI in their prescriptions. Of the 209 potential DDI, 26.3% were with a minimum of one major potential DDI. The median number of potential DDI per patient was 2.2. Overall, 296 potential DDI were identified in the current study. Among 296 identified potential drug-drug interactions, most of the interaction (49.7%) had good documentation. The number of medication prescribed per patient showed a significant (p< 0.001) association with the occurrence of potential DDIs.

Conclusion: More than half of the patients’ prescription contains potentially interacting medications. This study, additionally, revealed that there is a significant association between potential DDIs and number of medications prescribed per patient.

Key words: Drug-drug interactions, pharmacokinetic interaction, pharmacodynamic interaction, internal medicine
Kajian Ruang Publik Dan Isu Yang Berkembang Di Dalamnya
Authors: Hantono Dedi , Ariantantrie Nike
Published: November 2018

Ruang adalah bagian yang tak terpisahkan dari kehidupan manusia selama masa hidupnya. Bahkan konsepsi ruang tersebut masih ada pada manusia yang telah meninggalkan dunia ini walaupun konsepsi ruang itu sendiri sudah berbeda pada masing-masing penganut agama dan kepercayaan. Dari berbagai macam bentuk dan kategori seluruh ruang maka ruang publik adalah ruang yang paling banyak digunakan oleh semua orang baik sendiri maupun secara bersamaan. Begitu banyaknya aktivitas dan berbagai lapisan golongan masyarakat yang menggunakan ruang publik membawa interpretasi masing-masing yang cukup berbeda. Dari interpretasi inilah timbul begitu banyak ragam penggunaannya baik yang sesuai dengan fungsi maupun berdasarkan intrpretasinya masing-masing. Untuk memberi gambaran mengenai apa itu ruang publik maka dibuatlah suatu kajian dengan menganalisa beberapa tulisan dari beberapa artikel jurnal baik dalam maupun luar negeri. Dari kajian inilah nantinya didapat beberapa temuan yang bisa menjelaskan keberadaan ruang publik di dalam persepsi ruang lingkupnya.
Ionic-interaction of aqueous and alcoholic poly(vinyl alcohol) in the presence of protons
Authors: Naz Saima , Saeed Rehana
Published: November 2018

The ionic-interactions of acetic acid in H2O-PVOH and H2O-Alcohol-PVOH solvent systems were studied at different temperatures by viscosity method. The viscosities of the poly(vinyl alcohol) were increased with the increase in the concentration of poly(vinyl alcohol) and decreased with the increase in the concentration of acetic acid. The viscosity data were used to evaluate the ion-ion interactions and ion-solvent interactions in terms of ?A? and ?B? coefficients of the Jones-Dole equation respectively. The negative values of B-coefficient increased with increase in temperature showed that acid behaves as structure breaker in poly(vinyl alcohol)-solvent mixtures and consequently the values of A-coefficient were decreased with the rise of temperature. Thermodynamic parameters such as energy of activation (Ea*), free energy change of activation (?G*) and entropy change of activation (?S*) were also calculated as a function of acid (CH3COOH) concentration, poly(vinyl alcohol) composition, alcohols, and temperature.
“The Winter Oak”: Inspiring Passion for Teaching
Authors: Allen Robert D.
Published: November 2018

The purpose of this article is to inspire those who desire to improve their teaching effectiveness. A short story, “The Winter Oak” (Nagibin 1953), provides an organizing framework to articulate some of the most important factors involved in effective and influential teaching. Surrounding each of four parts of the story, I summarize research on the attributes of effective educators, discuss real-life, challenging situations and their outcomes, comment on lessons learned from “The Winter Oak,” and include stories of inspiring educators. These elements provide opportunities for reflection about the wonders of teaching and learning.
Metformin and Type 2 Diabetes Prevention
Authors: Aroda Vanita R. , Ratner Robert E.
Published: November 2018

IN BRIEF Metformin, an established therapy for the treatment of type 2 diabetes, has demonstrated safety and effectiveness in the prevention or delay of type 2 diabetes in people at high risk. The Diabetes Prevention Program randomized clinical trial demonstrated that intensive lifestyle intervention and metformin therapy reduced progression to diabetes by 58 and 31%, respectively, compared to placebo in people at risk of type 2 diabetes. Although lifestyle intervention was beneficial in all groups, metformin had a selectively greater effect in those who were more obese, had a higher fasting glucose, had a history of gestational diabetes, or were younger. Long-term effects included an 18% diabetes reduction with metformin compared to placebo over 15 years, a reduction in microvascular complications among those who did not progress to diabetes (without difference among treatment arms), and suggestion by coronary calcium assessment of a possible impact on atherosclerosis in men. Although long-term follow-up to assess later-stage outcomes is underway, current efforts to address gaps in evidence and translation remain of significant public health interest.
Social and Psychosocial Determinants of Health Associated With Uncontrolled Diabetes in a Federally Qualified Health Center Population
Authors: Rivich Julianna , Kosirog Emily R. , Billups Sarah J. , Petrie Jennifer L. , Saseen Joseph J.
Published: November 2018

Purpose.

Many people with diabetes have difficulty achieving glycemic targets, and social and psychosocial determinants of health may influence their ability to obtain glycemic goals. The objective of this study was to identify characteristics independently associated with A1C >9% or untested A1C compared to those with A1C ≤9% at a federally qualified health center.

Methods.

This retrospective cohort study included people with a diagnosis of diabetes, who were 18–89 years of age and had a medical evaluation from a primary care provider between 1 September 2016 and 31 August 2017. The primary outcome was to identify characteristics associated with an A1C >9% or untested A1C compared to those with an A1C ≤9%.

Results.

Of 6,185 patients meeting inclusion criteria, 2,965 (48%) had uncontrolled A1C. In the uncontrolled A1C group, 1,549 patients (52%) were female, 1,296 (44%) preferred care in a language other than English (1,273 [43%] in Spanish), and 535 (18%) had a concurrent mental health diagnosis. Multivariable logistic regression of 4,774 patients with complete data revealed that poor appointment adherence (odds ratio [OR] 3.24, 95% CI 2.30–4.57) and/or a positive Patient Health Questionnaire-2 depression screen (OR 1.35, 95% CI 1.12–1.62) had an increased risk of being in the uncontrolled A1C group. Patients with a prescription for antidepressant medication were more likely to be in the controlled group.

Conclusion.

Poor adherence to appointments and presence of depressive symptoms were associated with high A1C values. Interventions can be developed targeting these determinants to improve blood glucose levels.
Assessment of Herpes Simplex Virus Type 1 and 2 by IHC in Association with CD14 Antigen in Placental Tissues from Women with Miscarriage
Authors: A. Hamid Zainab , J. Ali Solaf , Hattem Hussain Ali
Published: November 2018

Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes. CD14 was implicated in immune mechanisms, and might be involved in pregnancy loss.  The aim of this study was to detect the possible occurrence of two HSV-1 and HSV-2 infections as well as the immunological factor cd14 in placental tissues from patients with spontaneous abortion using immunohistochemistry techniques. Immunohistochemistry technique assay was used to detect placental infection with HSV-1& HSV-2 as well as CD14 in 40 women with spontaneous miscarriage and in 40 healthy deliveries in Baghdad/Iraq. The IHC- expressions of HSV-1, HSV-2, and CD14 proteins were detected in 4(10%), 15(37.5%), 15(37.5%) in placental tissues from miscarriage women, respectively. The association between CD14 with HSV-1 and HSV-2 among the placental tissues from miscarriage patients was constituting (5%), (20%) with HSV-1 & HSV-2, respectively. The considerable proportion of HSV-1, HSV-2, and infections found in the placental tissues from miscarriage women could drag the attention of obstetricians to implicate these viruses as possible targets in the etiology of spontaneous abortion case and there is possible association of CD14 with HSV-1 and HSV-2 in women with abortion.
Prevalence and Knowledge about Genital and other Warts among Students in Sulaimani Polytechnic University: A cross-sectional study
Authors: Karadaghy Burhan , Mustafa Kamal Niaz , Othman Nasih
Published: November 2018

Genital warts and other warts are an epidermal manifestation attributed to the epidermotropic human papillomavirus (HPV) some of which have been linked directly to an increased neoplastic risk in men and women. According to our knowledge, research is scarce and little is known about this condition in Sulaimani city. A cross-sectional study was carried out from 1st April to 30th May 2018 including 441 undergraduate students aged between 18-30 years belonging to the health and non-health colleges of Sulaimani Polytechnic University. Data were obtained on the knowledge about genital warts through self-administrated questionnaire from the students. Data were analyzed using STATA 11. The mean age of the participants was 21.3 years. Hand warts were the commonest types among participants (31%). Knowledge score ranged from 0 to 9, was not normally distributed with a median of zero (IQR 0-22), 89% of the students had very low knowledge score. Knowledge score correlated with socio-demographic parameters were significantly higher in health students (P <0.001); outside Sulaimani city (P= 0.01) and students aged 21-30 (P <0.001). In general, it is highlighting the need for communication and education among students in order to overcome the lack of knowledge about genital warts and HPV infection. It also might reflect higher health consciousness among Sulaimani university students.
Dyslipidemia among Patients with End Stage Renal Disease on Maintenance Hemodialysis
Authors: Ghazi Abdulhadi Mohammed , Omer Mohammed Mohammed , Bakir Maarouf Fenk
Published: November 2018

Dyslipidemia has been suggested to be one of the factors that contribute to the high incidence of cardiovascular disease in hemodialysis patients. Previous studies suggest that end-stage renal disease may contribute to dyslipidemia. The aim of the study: to assess the prevalence of dyslipidemia in patients on maintenance hemodialysis. Patients and Methods: A case-control study was conducted from February 2015 until August 2015 in Ibn-Sena teaching hospital on 100 participants (52 males and 48 females), 50 were patients with end-stage renal disease on regular hemodialysis and 50 were age and gender-matched apparently healthy subjects as the control. Questioner used to collect data, a thorough examination was done including height and weight and BMI. A blood sample from all participants in fasting state was sent for the renal function test, complete blood picture, serum albumin, electrolytes, TG, total cholesterol, LDL and HDL measured by the enzymatic method, plasma atherogenic index calculated as [log (TG/HDL)].   Results: Age of the participants ranged between 18 - 70 years and the mean age was (44.45 ± 13.6) years. In HD group, the mean cholesterol  was  (3.29 + 0.73) mmol/l, serum TG (2.38 ± 0.56) mmol/l, LDL (1.91 ± 0.66) mmol/l, HDL (0.88 ± 0.2) mmol/l, atherogenic index (0.434 ± 0.16), while in control group, the mean cholesterol  was (4.17 ± 0.69) mmol/l, serum TG (1.6 ± 0.43) mmol/l, LDL (2.69 ± 0.63 ) mmol/l, HDL (1.066 ± 0.13) mmol/l, atherogenic index (0.177 ± 0.12).  The lipid abnormalities in hemodialysis group were high plasma atherogenic index in 84%, hypertriglyceridemia 50%, hypercholesterolemia 8% and high LDL  6% and low HDL in 48%, while in control group, high plasma atherogenic index in 34%, hypertriglyceridemia in 26%, hypercholesterolemia 14% high LDL 7% and low HDL in 16%. Conclusions: patients with end-stage renal disease on hemodialysis have significant dyslipidemia compared to control group characterized by hypertriglyceridemia, low HDL and high atherogenic index of plasma.
Üniversite Öğrencilerinin Yalnızlık ve Mükemmeliyetçilik Düzeyleri Arasındaki İlişkide Duygusal Zekânın Aracılık Rolü
Authors: KAYA Feridun , BİROL Zehra Nesrin
Published: November 2018

Bu araştırmada üniversite öğrencilerinin
mükemmeliyetçilik ve yalnızlık düzeyleri arasındaki ilişkide duygusal zekânın
aracı rolünün incelenmesi amaçlanmıştır. Araştırmanın çalışma grubunu
2016 / 2017 eğitim öğretim yılında Bayburt Üniversitesi’nde öğrenim gören 181’i
kadın, 125’i erkek, toplam 306 öğrenci oluşturmuştur.
Araştırmada veri toplama aracı olarak Kişisel Bilgi Formu, UCLA-Yalnızlık
Ölçeği, Frost - Çok Boyutlu Mükemmeliyetçilik Ölçeği ve Duygusal Zekâ
Özelliği Ölçeği – Kısa Formu kullanılmıştır. Araştırmadaki değişkenler
arasındaki ilişkileri ve dolaylı etkileri belirlemek için Pearson Korelasyon
Analizi ve Boostrap Yöntemi kullanılmıştır. Araştırmadan elde edilen sonuçlara
göre yalnızlık ile mükemmeliyetçilik arasında pozitif, duygusal zekâ ile
yalnızlık ve mükemmeliyetçilik arasında negatif yönde anlamlı bir ilişki
bulunmuştur. Son olarak yalnızlık ile mükemmeliyetçilik arasında duygusal
zekânın kısmı aracı rolü olduğu sonucu ortaya çıkmıştır.
Ebeveynlerin Psikolojik Hizmetlere Yönelik Tutumları Envanteri: Türkçe Formunun Geçerlik ve Güvenirlik Çalışması
Authors: BAŞDAŞ Erdal , TÜRKÜM Ayşe Sibel
Published: November 2018

Bu çalışmanın
amacı, Turner (2012) tarafından geliştirilen, Ebeveynlerin Psikolojik Hizmetlere
Yönelik Tutumları Envanterini (EPHYTE) Türkçeye uyarlamak ve psikometrik
özelliklerini incelemektir. Araştırma 5-9 yaş aralığında, en az bir çocuğu olan
iki farklı çalışma gurubundan anne ve babalar (N1=433; N2=56)
ile yürütülmüştür. Açımlayıcı faktör analizi sonucunda envanterin Türkçe
formunun toplam varyansın %53’ünü açıkladığı ve özgün formda olduğu gibi üç
boyutlu bir yapıya sahip olduğu belirlenmiştir. Doğrulayıcı faktör analizi
sonucunda, 21 madde ve üç alt boyuttan (psikolojik yardım aramaya ilişkin
niyet, yardım almaya ilişkin tutum, etiketlenme) oluşan modelin iyi uyum
verdiği görülmüştür (χ2 (186, N = 433) = 476,82, χ²/df=
2.564, p < .001; GFI = 0.91; CFI = 0.92; TLI = 0.91; SRMR = 0.055; RMSEA =
0.060). Envanterin faktör yükleri .28 ile .81, madde toplam korelasyon
katsayıları .25 ile .67, test-tekrar test korelasyon katsayıları .69 ile .78, iç
tutarlılık güvenirlik katsayıları ise .80 ile .88 arasında değişmektedir. Sonuçlar,
envanterin Türkçe formunun geçerli ve güvenilir bir envanter olduğunu
göstermektedir.
Johann Arndt in Anhalt (1581–1590): worldview search
Authors:   Lipetsk State Pedagogical University, Melnikov Denis Valerievich ,   Ss Cyril and Methodius School of  Post-Graduate and Doctoral Studies
Published: November 2018

The paper examines the least studied period of the works of the great German mystic, theologian, philosopher, doctor and alchemist J. Arndt. The hypothesis of the correspondence between J. Arndt and V. Weigel and the participation of J. Arndt in the works of the students of V. Weigel are rejected. The point of view of Professor W. Breul is adjusted, and the difference between the views of J. Arndt and the position of Lutheranism is proved. Seemingly keeping away from the concepts of Paracelsus, a famous natural philosopher of the Renaissance era, and converging with the Lutheranism, the pastor of Badeborn remained faithful to the doctrine of Paracelsus and independently developed some intuition of the latter. In the doctrine of the Eucharist, J. Arndt agreed with the physical presence of Christ in the Sacrament, and it corresponded to the views of both Paracelsus and M. Luther. Unlike the Lutheran theologians, J. Arndt emphasized the necessity and the power of exorcism in the sacrament of baptism that could be explained by some gnostic intuition of Paracelsus. While searching for his place in the Lutheran worldview, J. Arndt demonstrated creative independence that could help him create a unique work “True Christianity”.
Did Kant’s third critique suggest that transcendent supersensible objects of cognition and goal-setting exist?
Authors:   Surgut State University, Burkhanov Rafael Ayratovich
Published: November 2018

The study analyzes the existence problem of supersensible objects in “Critique of Judgment” by Immanuel Kant, where the power of judgment is understood as a transition from the pure theoretical ability to cognize to the practical concept of freedom. The research notes that the metaphysical problem statement implies the highest supersensible basis of the unity of the diverse and the integration of the unit diversity into a single universal system of laws and results of nature. The author emphasizes that all particular empirical laws should be considered as a kind of unity as if such unity gives the nature the supreme, divine, transcendent mind rather than human, transcendental one. Nevertheless, people as reasonable beings are able to cognize nature by the causality of the natural laws of matter instead of the ultimate causes and goals of nature. Rejecting the intellectual intuition, Kant argued that our knowledge was always based on experience. Therefore, in “Critique of Judgment”, he did not recognize the existence of transcendent supersensible objects of cognition and goal-setting. The philosopher believed that the unified supersensible basis for nature and freedom conceived by us, gave no real grounds for comprehending the transcendent things in ourselves. However, it allowed us to have in our heart the ideal of knowledge of the theoretical reason and the moral ideal of the practical reason.
Tercih sürecinde üniversitelerin sosyal medya kullanımı
Authors: AKYAZI Erhan
Published: November 2018

Yeni kuşakların toplumda yerlerini alabilmeleri için gerekli bilgi ve
becerileri elde etmelerine yardım etme etkinlikleri kısaca eğitim olarak
adlandırılmaktadır. İnsan sosyal bir varlıktır ve toplumdan ayrı düşünülemez.
Topluma adapte olabilmesi için gerekli eğitim faaliyetlerine katılması doğaldır
ve bir haktır. Bu hak gerek uluslararası, gerekse ulusal yasa ve sözleşmelerde
kayıt altına alınmıştır. Birleşmiş Milletler Genel Kurulu’nun 1948 yılında
kabul etmiş olduğu İnsan Hakları Evrensel Beyannamesi’nin 26. maddesi her
şahsın öğrenim hakkı olduğunu belirtmektedir. Türkiye Cumhuriyeti Anayasası’nın
42. maddesinde de kimsenin eğitim ve öğrenim hakkından mahrum bırakılamayacağı
belirtilmektedir. Devletlerin görevi eğitim kurumları açmak, bu kurumlara
eğitim personelleri görevlendirmek ve vatandaşlarının ilgili haklardan
yararlanmasına sağlamaktır. Özel kurumlar tarafından açılan eğitim kurumları da
bu görevde devletin sorumluluğunu hafifletmektedir. Ülkemizde de ilköğretim
seviyesindeki milyonlarca öğrenci için binlerce okul açılmış durumdadır. Her
şehirde en az bir adet olmak üzere onlarca yükseköğretim kurumu açılmıştır ve
açılmaya da devam etmektedir. Halihazırda Yükseköğretim Kurulu bünyesinde 206
Yükseköğretim Kurumu yer almaktadır. Her yükseköğretim kurumunun temel görevi
topluma nitelikli mezunlar kazandırabilmektir. Bu görevini yerine getirirken de
en başarılı adayların kendilerini tercih etmesi için yarışmaktadırlar. Başarılı
adayları kendine çekmek öncelikle onlara ulaşmayı gerektirmektedir. 90’lı
yılların sonu ile birlikte hayatımıza giren iletişim ve bilişim
teknolojilerinin yardımı ile bireylere erişmek oldukça kolaylaşmış, kapsamı da
bir o kadar genişlemiştir. Yeni milenyum ile iletişime bir başka boyut katan
sosyal medya ise hayatımızın her alanına nüfuz ettiği gibi, yükseköğretim
kurumlarına da yeni imkanlar sunmuştur. Kurumlar iletilerinin hedef kitlelerine
ulaşıp ulaşmadığını denetleyebilmekte, ulaştığı kitlenin profilini görebilmekte
ve böylece bir sonraki içeriklerini daha planlı oluşturabilmektedirler.
Günümüzde hemen hemen tüm yükseköğretim kurumunun en az bir sosyal medya
hesabının olduğunu söylemek yanlış olmayacaktır. Rekabet ortamının
zorlayıcılığının sonucu olan bu durum adaylara tercihlerini yapmada kolaylıklar
sağlamaktadır. Mobil cihazlar ve operatörlerin desteği ile hayatımızın her
alanına girmiş olan sosyal medya bunun kaynağını oluşturmaktadır. Bu kapsamda
çalışma üniversitelerin sosyal medya mevcudiyetlerini ve tercih sürecinde
sosyal medya platformlarını kullanma performanslarını ölçmeyi amaçlamaktadır.
Bu çerçevede, çalışmada İstanbul’daki üniversitelerin adaylara yönelik sosyal
medya paylaşımları analiz edilmeye çalışılacaktır.
The Importance of Sustainability Reports In Non-Financial Companies
Authors: Shinta Melzatia Caturida.M.Doktoralina, Dewi Anggraini,Safira,
Published: November 2018

The sustainability report (SR) has become a necessity for companies. Its role is crucial for the development of a company because it includes both social and environmental aspects. However, there are still companies that have not properly conducted sustainability report disclosures (SRDs). Therefore, this study aims to examine the effects of profitability, leverage and liquidity on SRDs. In particular, we explore the implications of regulations that require the disclosure of environmental and social information in non-financial companies listed on the Indonesia Stock Exchange (IDX) in 2013-2017. The sample in this study was 65 from 13 companies that met the criteria, and the study utilised the purposive sampling method. The study results found that first, profitability proxied by return on assets (ROA) did not significantly influence SRDs. Second, leverage proxied by debt to assets ratio (DAR) has a significant negative effect on SRDs, and third, the liquidity proxied by the current ratio (CR) has a significant negative effect on SRDs. The results of this study are expected to increase knowledge for readers, especially investors, so they can pay better attention to a company's social and environmental activities when investing.
Mathematical behavior of the solutions of a class of hyperbolic-type equation
Authors: PİŞKİN Erhan , YÜKSEKKAYA Hazal
Published: November 2018

In this paper, we consider hyperbolic-type equations with initial and Dirichlet boundary conditions in a bounded domain. Under some suitable assumptions on the initial data and source term, we obtain nonexistence of global solutions for arbitrary initial energy.
Rancang Bangun Sistem Manajemen Budidaya Ayam Broiler Berbasis Web Menggunakan Metode Prototyping
Authors: Fani Ridho Hawali , Surya Ibnu , Adin Saf Maksum Ro'is
Published: November 2018

Beternak dengan sistem kemitraan merupakan suatu bentuk usaha yang sedang marak saat ini, beternak secara kemitraan merupakan bentuk kerja sama antara peternak dengan perusahaan. Hasil panen akan dibagi sesuai persenan yang telah disepakati pada Memorandum of Understanding (MoU). Dibutuhkan waktu lebih kurang 4-6 minggu bagi peternak untuk memelihara ayam hingga panen. Selama periode tersebut, peternak harus merawat ayam dengan maksimal sehingga diharapkan hasil panen menguntungkan bagi peternak dan perusahaan tersebut. Maka dari itu, sistem  ini dibangun agar dapat mengatasi permasalahan seperti pemberian pakan atau vaksin yang tidak teratur, pencatatan perkembangan ayam tiap hari yang masih dilakukan secara manual, penanganan penyakit dan kurangnya wawasan terhadap penyakit yang sering didapatkan oleh ayam, serta penghitungan timbangan yang masih dilakukan secara manual. Sehingga dengan mengatasi permasalahan tersebut hasil panen menjadi meningkat dan tingkat produktifitas ayam menjadi terkendali. Tools yang digunakan dalam pembuatan sistem ini adalah Visual Studio 2017. Setelah dilakukan pengujian selama tiga periode ternak, sebanyak 82.6% responden dari sepuluh orang yang merupakan peternak ayam broiler menyatakan sistem tersebut dapat meningkatkan efisiensi dalam beternak ayam broiler.
Sistem Pengawasan Keuangan Badan Usaha Milik Desa (BUM Des) berbasis Android
Authors: Farokhah Lia , Sapoetra Yudistira Arya
Published: November 2018

Program  pemerintah untuk peningkatan potensi desa dalam bentuk badan usaha milik desa (BUM Des) sedang digalakkan dengan serius. Pemerintah menganggap ini adalah salah satu cara mengentaskan kemiskinan dengan cara peningkatkan kesejahteraan dan memandirikan desa secara keuangan. Namun, ada banyak masalah yang ada di lapangan seperti kekurang percayaan pengurus internal BUM Des sendiri terhadap kelembagaan BUM Des. Hal ini menyebabkan banyak desa yang ragu dalam mendirikan BUM Des atau BUM Des yang sudah berdiri namun tidak berkembang. Masalah transparansi merupakan masalah yang paling utama dalam kelembagaan BUM Des. Sistem kepercayaan, pengelolaan dan transparansi keuangan serta pembagian hasil hasil usaha yang menjadi pokok tujuan hampir setiap BUM Des yaitu kesejahteraan. Dalam perancangan aplikasi pengawasan keuangan BUM Des mendapatkan hasil umpan balik sebesar sebesar 82,77%. Hal ini menunjukkan hasil umpan balik yang dianggap sangat positif.
Aplikasi Informasi Harga Kebutuhan Pokok Masyarakat Real Time
Authors: Hernawati Elis , Rosely Ely , Handini Rosa Wulan
Published: November 2018

Dalam rangka mewujudkan  visi kabupaten Bandung untuk meningkatkan penyampaian informasi kinerja pemerintah melalui media diseminasi informasi sesuai Standar Pelayanan Minimal (SPM) Bidang Kominfo dan meningkatkan ketersediaan data dan informasi statistik yang berkualitas, penelitian ini membangun sebuah aplikasi berbasis web yang dapat menyajikan informasi harga kebutuhan pokok masyarakat secara realtime di Kabupaten Bandung. Aplikasi dibangun untuk membantu petugas diskominfo kabupaten Bandung ketika akan menginformasikan daftar harga kebutuhan bahan pokok secara uptodate. Selain itu aplikasi dapat membantu masyarakat ketika mencari informasi mengenai harga kebutuhan pokok di Kabupaten Bandung sehingga tidak perlu mendatangi kantor diskominfo. Metode yang digunakan dalam penelitian ini adalah metode waterfall. Metode ini digunakan karena proses dilakukan secara bertahap dan berurutan dari mulai analisis hingga pengujian aplikasi sehingga kualitas aplikasi yang dihasilkan akan baik. Implementasi pembuatan aplikasi menggunakan Framework Codeigniter, dengan bahasa pemograman PHP,  serta software pengolah databasenya MySQL. Metode pengujian software menggunakan black box testing. Dengan adanya aplikasi ini masyarakat dapat mengetahui informasi harga kebutuhan pokok dengan mudah dan uptodate.
Giant Star-Shaped Nitrogen-Doped Nanographenes
Authors: Mora-Fuentes Juan P. , Riaño-Carnerero Alberto , Cortizo-Lacalle Diego , Saeki Akinori , Melle-Franco Manuel , Mateo-Alonso Aurelio
Published: November 2018

Star-shaped nanographenes are large monodisperse polycyclic aromatic hydrocarbons that extend in size beyond the nanometer and have shown a lot of promise in a wide range of applications including electronics, energy conversion and sensing. Herein we report a new family of giant star-shaped N-doped nanographenes with diameters up to 6.5 nm. Furthermore, the high solubility of this SNG family in neutral organic solvents at room temperature allowed a complete structural, optoelectronic and electrochemical characterisation, which together with charge transport studies illustrate their n-type semiconducting character.
A Volatile Dialane Complex from Ring-Expansion of an N-Heterocyclic Carbene and its Use in Atomic Layer Deposition of Aluminum Metal Films
Authors: Blakeney Kyle , Martin Philip , Winter Charles
Published: November 2018

Treatment of the stable N-heterocyclic carbene (NHC) 1,3-di-tert-butylimidazolin-2-ylidene with two equivalents of AlH3(NMe3) afforded the structurally unusual ring expanded dialane complex 1 in 72% yield after sublimation. Complex 1 has a distorted norbornane-like C3N2Al2 core with two pseudo-tetrahedral Al dihydride sites. Treatment of 1 with Cp2TiCl2 as a model for metal thin film precursors produced the hydride-bridged Ti(III)-Al heterobimetallic complex 2 in 45% crystalline yield. Complex 1 shows good volatility and thermal stability, subliming at 90-100 °C and 50 mTorr and decomposing in the solid state at ~200 °C. The vapor pressure of 1 is 0.75 Torr at 120 °C. These physical properties are promising for a potential atomic layer deposition (ALD) precursor. Aluminum metal films were deposited by thermal ALD using AlCl3 and 1 as precursors with a growth rate of ~3.5 Å/cycle after 100 cycles within an ALD window between 120-140 °C. The films are crystalline aluminum metal by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analysis showed aluminum metal with 7.0 at.% C, 3.6 at.% N, and 0.9 at.% Cl impurities. The aluminum metal films had an electrically discontinuous morphology. Conductive aluminum metal films have been deposited under similar conditions using a different aluminum hydride reducing co-reactant, which highlights the impact that small precursor differences can have on film characteristics.
Nitrogenoa: iragana eta orainaldia konektaturik
Authors: Barona Fernandez Astrid , Etxebarria Robledo Begoña , Díaz Tena Estibaliz , Rojo Azaceta Naiara , Gallastegui Ruiz de Gordoa Gorka
Published: November 2018

Airearen osagai nagusia den nitrogeno gasak lotura historiko estua du gizartearen garapen ekonomiko, sozial eta politikoarekin, amoniakoaren sintesian izan duen protagonismoa dela-eta. 1908. urtean Fritz Haber-ek lorturiko amoniakoaren sintesia kimikaren mugarri zientifikoa izan zen, eta, aldi berean, aurkako helburuak zituzten sektore industrial askoren garapena goitik behera aldatu zuen aurkikuntza horrek, hala nola biztanleriaren hazkundea bermatzen zuten laborantza-ongarrien ekoizpena eta gerra-xederako fabrikatzen ziren lehergaien industria erabat transformatu zituen. Egia esan, XX. mendearen hasierako hamarkadetako arazoak konpontzeko aurrerapen itzela izan zen, eta oraindik ere sintesi-prozesu horren menpe bizi gara. Ez du ordezkorik, baina kontuan izan behar dugu haren inpaktu ekologikoa jasanezina dela eta gaur egun ingurumenarekiko kalteak agerian daudela. Beraz, historian zehar amoniakoaren sintesiaren berrikuntza historikoak gizateriaren alde eta kontra eragin dituen ondorioak eta kontraesanak erakustea da artikulu honen helburua.
Análisis de la escritura de docentes jubilados del Ministerio de Educación en las redes sociales: Facebook y WhatsApp
Authors: Britos Bogado María Amelia
Published: November 2018

El estudio de la escritura de los docentes jubilados del Ministerio de Educación y Ciencia del Paraguay en las redes sociales a partir del análisis del discurso, principalmente en las páginas de Facebook y en el tipo de mensajería de los grupos de Whatsapp surgió como una preocupación, dado que el lenguaje representa las características socioculturales de la persona y una escritura con evidentes limitaciones en el aspecto ortográfico, gramatical y semántico deja mucho que desear y sobre todo genera una descalificación de parte de la sociedad, debido a que se espera del docente un lenguaje culto, correcto y delicado. El objetivo fue identificar y analizar estas debilidades y proponer mecanismos para mejorar la calidad de la escritura de los docentes en las redes sociales a partir de la práctica continua de la escritura. Fueron seleccionados en forma intencional 50 mensajes de texto de ambas fuentes mencionadas, docentes jubilados, entre ellos, ex directores y supervisores. El estudio es descriptivo cualitativo. Se describe la escritura de los docentes desde el punto de vista de la construcción del discurso (organización de ideas, precisión del contenido), la gramática (aspectos sintácticos, semánticos y morfológicos), la ortografía y la puntuación. Se hallaron errores de diferentes aspectos de la ortografía y la gramática, el mayor porcentaje se dio en la falta de acentuación ortográfica y de puntuación, igualmente la escasa profundidad del contenido de los mensajes.
Tutoría Académica Universitaria: Percepción de estudiantes de la Facultad de Odontología. Universidad Nacional de Asunción
Authors: Benítez Stela Mary
Published: November 2018

La tutoría universitaria es un factor de calidad y una exigencia del Espacio Europeo de Educación Superior. Forma parte del sistema de gestión de calidad de la educación. Es un acompañamiento personalizado, desde el inicio de la vida universitaria, como apoyo para el desarrollo de actitudes personales y profesionales. Ayuda a la formación crítica, responsable y participativa del discente en la sociedad, favoreciendo el aprendizaje de valores y actitudes sin dejar de lado conocimientos y habilidades. En el 2011, se creó en la Facultad de Odontología de la Universidad Nacional de Asunción, dicho Programa como una estrategia, enfocada a la formación integral del estudiante. Su objetivo fue elevar la calidad del proceso educativo, brindando atención personalizada, con miras a identificar problemas que influyen en el desempeño social y académico. Se realizó una investigación, descriptiva de corte trasversal, con enfoque cuantitativo. El objetivo fue determinar la percepción de los estudiantes,    sobre el programa. Participaron 73 estudiantes, de primer al tercer curso, voluntariamente. Se aplicó un cuestionario cerrado, autoadministrado. Resultados, solo 46,6% de los tutorados refirió satisfacción respecto al programa de tutoría. El nivel de empatía del tutor fue buena (59%). La disposición de los tutores fue bueno (62,8%) y la  percepción en cuanto a la capacidad tutorial fue deficiente (< 50%). Aspectos que denotan que se tiene que mejorar muchos aspectos en los tutores, como una mayor capacitación para asumir su rol.
Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017
Authors: Plachouras Diamantis , Kärki Tommi , Hansen Sonja , Hopkins Susan , Lyytikäinen Outi , Moro Maria Luisa , Reilly Jacqui , Zarb Peter , Zingg Walter , Kinross Pete , Weist Klaus , Monnet Dominique L. , Suetens Carl ,   the Point Prevalence Survey Study Group
Published: November 2018

Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016–17, we performed the second point-prevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2–31.9%). The most common indication for prescribing antimicrobials was treatment of a community-acquired infection, followed by treatment of HAI and surgical prophylaxis. Over half (54.2%) of antimicrobials for surgical prophylaxis were prescribed for more than 1 day. The most common infections treated by antimicrobials were respiratory tract infections and the most commonly prescribed antimicrobial agents were penicillins with beta-lactamase inhibitors. There was wide variation of patients on antimicrobials, in the selection of antimicrobial agents and in antimicrobial stewardship resources and activities across the participating countries. The results of the PPS provide detailed information on antimicrobial use in European acute care hospitals, enable comparisons between countries and hospitals, and highlight key areas for national and European action that will support efforts towards prudent use of antimicrobials.
Minimising the Deep Coalescence
Authors: Dąbkowski Dawid , Gorecki Pawel
Published: November 2018

Metagenomic studies identify the species present in an environmental sample usually by using procedures that match molecular sequences, e.g., genes, with the species taxonomy. Here, we formulate the problem of gene-species matching in the parsimony framework using phylogenetic gene and species trees under the deep coalescence cost and the assumption that each gene is paired uniquely with one species. In particular, we solve the problem in the cases when one of the trees is caterpillar. Next, we generalize the solution and propose several heuristic algorithms. Finally, we present the results of computational experiments on simulated and empirical datasets.
Reduction of modern problems of mathematics to the classical Riemann-Poincare-Hilbert problem
Authors: Durmagambetov Asset
Published: November 2018

Using the example of a complicated problem such as the Cauchy problem for the Navier--Stokes equation, we show how the Poincar\'e--Riemann--Hilbert boundary-value problem enables us to construct effective estimates of solutions for this case. The apparatus of the three-dimensional inverse problem of quantum scattering theory is developed for this. It is shown that the unitary scattering operator can be studied as a solution of the Poincar\'e--Riemann--Hilbert boundary-value problem. This allows us to go on to study the potential in the Schr\"odinger equation, which we consider as a velocity component in the Navier--Stokes equation. The same scheme of reduction of Riemann integral equations for the zeta function to the Poincar\'e--Riemann--Hilbert boundary-value problem allows us to construct effective estimates that describe the behaviour of the zeros of the zeta function very well.
Klasifikasi Mahasiswa Penerima Program Beasiswa Bidik Misi Menggunakan Naive Bayes
Authors: Farida Yuniar , Ulinnuha Nurissaidah
Published: November 2018

Program beasiswa Bidik Misi merupakan program bantuan biaya pendidikan yang diberikan oleh Kementrian Riset Teknologi dan Pendidikan Tinggi kepada mahasiswa yang memiliki tingkat ekonomi menengah ke bawah namun memiliki potensi akademik yang baik. Universitas Islam Negeri Sunan Ampel Surabaya merupakan perguruan tinggi dengan jumlah pendaftar Bidik Misi yang terus meningkat setiap tahunnya namun hanya menerima dengan kuota yang sangat terbatas. Dengan banyaknya persyaratan dalam proses penyeleksian dan melihat banyaknya jumlah pendaftar, maka diperlukan sebuah sistem yang mampu membantu dalam proses penyeleksian mahasiswa pendaftar Bidik Misi dengan cepat, mudah dan tepat sasaran. Dalam penelitian ini, digunakan metode Naive Bayes classifier dengan menggunakan variabel penghasilan orang tua, prestasi akademik, prestasi non akademik, uang kuliah tunggal, daya listrik serta jumlah tanggungan keluarga. Keenam variabel tersebut digunakan dalam proses klasifikasi sebagai indikator penentuan kelayakan mahasiswa mendapatkan beasiswa. Sistem yang dibuat dengan metode Naive Bayes classifier sudah baik, dibuktikan dengan hasil akurasi hingga 83,33 %.