bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of sugammadex in endovascular interventions on cerebral vessels
Authors: Prasolov N. V. , Shulutko E. M. , Vasiliev A. E. , Gitelson D. G.
Published: October 2022

Highlights. The article discusses the features of general anesthesia in patients with cerebrovascular diseases using the relaxant binding agent sugammadex.

Aim. To evaluate the effectiveness of sugammadex in endovascular management of cerebrovascular diseases.

Methods. The study included 57 patients who underwent endovascular treatment of cerebrovascular disease under general anesthesia. The experimental group included 29 patients who were injected with sugammadex - a selective relaxant binding agent for reversal of neuromuscular block induced by rocuronium. The comparison group included 28 patients who did not undergo decurarization (n = 13), or it was performed with neostigmine (n = 15). Acceleromyography was used to monitor the state of neuromuscular function.

Result. Onset of action and duration of action of rocuronium at a dose of 0.9 mg/kg did not differ between the groups. The neuromuscular recovery time was 2.14 [1.67; 2.59] minutes after administration of sugammadex, compared with spontaneous 35.8 [31.5; 40.4] minutes and neostigmine-induced 22.1 [16.8; 27.3] minutes (p<0.001). No adverse or allergic reactions were noted after administration of the relaxant binding agent.

Conclusion. Using a specific antidote sugammadex to eliminate the effect of rocuronium helps to restore neuromuscular function within 2–3 minutes and assess the neurological status of patients immediately after the endovascular treatment of cerebrovascular disease.
Non-invasive methods of in vivo functioning analysis of the “TiAra” stentless valve prosthesis
Authors: Onishchenko P. S. , Klyshnikov K. Yu. , Ovcharenko E. A. , Stasev A. N. , Kokov A. N. , Brel N. K. , Yevtushenko A. V. , Barbarash L. S.
Published: October 2022

Highlights. Non-invasive method for the assessment of the mobility and deformation of the wire element of the bioprosthesis in the cardiac cycle based on the developed mathematical algorithm is presented. Numerical analysis of the behavior of the wire element of the “TiAra” bioprosthesis is shown for the first time. The developed method can be used for other medical devices as well.

Aim. To develop a method for non-invasive assessment of the mobility and deformation of the wire element of the aortic heart valve bioprosthesis in the cardiac cycle based on mathematical processing of visual medical data.

Methods. Multidetector computed tomography data of patient P. (male, 66 years old), who received the “TiAra” aortic bioprosthesis (NeoCor CJSC, Kemerovo), were used for the study. Using the built-in tools in the Mimics Medical Image Processing Software (Materialize, Belgium), based on the radio density, 5 stages of movement of  the  wire  element  of  the  bioprosthesis  were  reconstructed  in  the  form  of 3D-models.  The  differences between  the  models,  characterizing  deformation in the cardiac cycle, were quantitatively assessed using a proprietary Matlab algorithm (The MathWorks, USA), calculating the distance between similar points. Moreover, obtained data on displacements was used in the numerical study of the stress-strain state of a 3D-model of the wire element by the finite element method in the Abaqus/CAE software (Dassault Systèmes SE, France).

Results. The proposed method for assessing the mobility of the wire element made it possible to quantitatively evaluate the biomechanics of the “TiAra” stentless bioprosthesis based on multidetector computed tomography, a non-invasive clinical tool. The movements that the bioprosthesis undergoes during the cardiac cycle (the maximum value is 2.04 mm in the radial direction) are comparable to the movement of the aortic root of a healthy patient. The results of the numerical modeling of the stress state of the wire element did not indicate high amplitudes (peak value – 564 MPa) that would be capable of causing critical damage to the wire. It allows us to confirm the clinical safety of the bioprosthesis in real conditions like asymmetric and uneven loads. Moreover, deformations observed in the bioprosthesis are similar in the amplitude to the displacements of the aortic root described in the literature, which highlights the main feature of the bioprosthesis – ensuring the physiological biomechanics throughout the cardiac cycle.

Conclusion. The presented method of qualitative computer assessment of the movement of the wire element of heart valve prosthesis using the “TiAra” bioprosthesis as an example demonstrates its validity as a tool for studying prosthesis functioning.
Impact of CYP2C19 gene polymorphisms on clinical outcomes in patients with myocardial infarction during 12-month follow-up
Authors: Grazhdankin I. O. , Baystrukov V. I. , Kretov E. I. , Prokhorikhin A. A. , Chernyavsky A. M.
Published: October 2022

Highlights. CYP2C19 gene polymorphisms in patients with acute myocardial infarction are common in clinical practice. The article assesses the role of genetic predisposition in the development of ischemic and hemorrhagic events during dual antiplatelet therapy (aspirin and clopidogrel) within the first 12 months after revascularization for acute myocardial infarction.

Aim. To evaluate the impact of CYP2C19 gene *1, *2, *3, *17 alleles polymorphism on 12-month clinical outcomes in patients who underwent coronary revascularization due to acute myocardial infarction and took clopidogrel.

Methods. 363 patients with acute myocardial infarction undergoing percutaneous coronary intervention were enrolled in the prospectively study in 2010–2012. CYP2C19 gene *1, *2, *3, *17 alleles polymorphism analysis was performed in all study participants. Dual antiplatelet therapy, consisting of aspirin and clopidogrel, was prescribed for 12 months. The follow-up period was 12 months, the incidence   of cardiovascular death, non-fatal myocardial infarction, stroke and bleeding was assessed.

Results. 12 months after inclusion in the study, the incidence of composite endpoint (defined as cardiovascular death, non-fatal myocardial infarction and stroke) was observed in 18 patients (7% [5%; 11%]; 95% CI) with wild-type CYP2C19 gene and in 12 patients (11% [6%; 18%]; 95% CI) with lost-of-function *2+*3 alleles, with no statistical difference (OR = 1.6 [0.7; 3.6], 95% CI; p = 0.301). Presence of any LOF-alleles did not predict composite endpoint events (OR = 1.56 [0.71; 3.34], 95% CI, p<0.253). Multivariable logistic regression analysis revealed that CYP2C19*2 homozygotes have higher risk of composite endpoint (OR = 6.34, 95% CI [1.57; 22.23], p<0.005) and myocardial infarction (OR = 5.45, 95% CI [1.14; 19.97], p<0.016) compared to *2 heterozygotes and wild-type carriers.    14 patients had major bleedings, required blood transfusion or hospitalization. Patient’s age, increase in creatinine level and gain-of-function (GOF) CYP2C19*17 homozygotic carriage were identified as the predictors of major bleeding during follow-up period.

Conclusion. In this study CYP2C19 LOF alleles polymorphism except the CYP2C19*2 homozygotic carriage demonstrated no impact on the incidence of ischemic events during 12-month follow-up in patients with acute MI who underwent successful revascularization. CYP2C19*17 homozygotes demonstrated increased risk of major bleeding only in young individuals with elevated blood creatinine levels.
Endovascular treatments for ischemic stroke
Authors: Malaev D. U. , Grachev N. I. , Redkin D. A.
Published: October 2022

Highlights. Mechanical thrombectomy is the “gold standard” treatment of patients with large-vessel occlusions. Five randomized trials conducted in 2015 made a significant contribution to the development and introduction of mechanical thrombectomy into clinical practice. The DAWN and DEFUSE-3 trials have provided new insights into the pathophysiology of ischemic stroke and ensured the advancement in the therapeutic field.

Abstract. Stroke is one of the leading causes of death and disability worldwide. The general strategy for the treatment of ischemic stroke is aimed at restoring blood flow to the ischemic regions of the brain. Intravenous thrombolysis has been the treatment for acute ischemic stroke since 1996. However, since 2015, as a result of 5 randomized trials, endovascular mechanical thrombectomy has become the gold standard for the treatment of patients with large cerebral artery occlusion. The DAWN and DEFUSE 3 trials have provided new insights into the pathophysiology of ischemic stroke, shifting the paradigm from “time = brain” to “collaterals = brain”. In this article, the authors will consider development of endovascular devices, modern mechanical thrombectomy techniques, and directions for further research of endovascular treatment for ischemic stroke.
Recurrent myocardial infarction: clinical, anamnestic and epidemiological aspects
Authors: Okrugin S. A. , Repin A. N.
Published: October 2022

Highlights. Recurrent myocardial infarction remains an important health problem due to the high mortality of patients. At the same time, there is practically no data in the literature on the prevalence of this complication in the population, which makes studies carried out on the basis of long-term epidemiological programs relevant. The analysis of the “Acute Myocardial Infarction Register” (Tomsk) presented in the paper showed not only a high mortality rate of patients with recurrent infarction, but also a tendency to increase the incidence of this complication, which confirms the need to search for predictors of its occurrence.

Aim. To determine the incidence of recurrent myocardial infarction (RMI) and mortality in patients with RMI in Tomsk for five years (2016–2020), to perform a clinical and anamnestic analysis of RMI episodes registered in 2019 and 2020.

Methods. The study was performed on the basis of the data from the information and analytical database of the WHO program “Registry of Acute Myocardial Infarction”. In 2019–2020 1748 cases of acute myocardial infarction (AMI) were registered, in 1078 men (61.7%) and 670 women (38.3%). 87 patients with RMI were identified, which accounted for 5%. In this group, there were 46 men (52.9%) and 41 (47.1%) women. The age of RMI patients was almost identical (72.2±12.7 years old in men and 72.1±11.4 years old in women).

Results. 51 (58.6%) patients were hospitalized with index AMI in a specialized department, 14 (16.1%) were treated in non-core hospitals and 22 (25.3%) people died at the prehospital stage. Patients with AMI with RMI and without RMI did not differ in clinical and anamnestic parameters. Coronary ventriculography was performed in 51 (58.6%) patients with RMI, in 41 (80.4%) cases there was a multivessel lesion of the coronary bed. RMI occurred in 43 (49.4%) patients who were treated in hospital, in 22 (25.3%) – at home, after discharge. RMI was detected in 22 (25.3%) of the dead at the prehospital stage. Typical and atypical clinical manifestations of RMI occurred in 53% and 47%, respectively. Stent thrombosis (24.1%) and the lack of treatment for indexAMI (35.6%) prevailed among the causes of RMI. It was not possible to establish the cause in 27.6% of cases. An increase in the incidence of RMI was noted from 2016 to 2020. During the follow-up, the mortality rate from RMI was two times higher than that among AMI patients in general.

Conclusion. There were no significant clinical, anamnestic and other differences among patients with and without RMI. The established causes of RMI are not so much causes as a consequence of some factors. This fact, combined with the high mortality rate from RMI and the trend towards an increase in the incidence of RMI, makes it necessary to search for predictors of the onset of RMI and ways to prevent them.
Prognostic value of matrix metalloproteinases in patients with anthracycline-induced heart failure
Authors: Teplyakov A. T. , Shilov S. N. , Grakova E. V. , Kopeva K. V. , Bobyleva E. T. , Berezikova E. N. , Popova A. A. , Samsonova E. N.
Published: October 2022

Highlights. Elevated levels of matrix metalloproteinases 2 and 9 are associated with the initiation and severity of CHF developed after breast cancer therapy with anthracyclines, which may contribute to cardiac remodeling and the progression of systolic dysfunction. Concentrations of matrix metalloproteinases-2 and -9 in blood serum serve as predictors of the unfavorable course of anthracycline-induced heart failure.

Aim. To assess the role of matrix metalloproteinases-2 (MMP-2) and 9 (MMP-9) in the development and course of anthracycline-induced chronic heart failure (CHF) during 24 months of observation.

Methods. The study included 114 women 12 months after completion of chemotherapy (CT) for breast cancer and developed CHF. The control group (n = 70) consisted of women (mean age 45.0 [42.0; 50.0] years old) who received doxorubicin as part of chemotherapy, but they did not develop CHF 12 months after completion of chemotherapy. The levels of biomarkers (MMP-2, MMP-9, NT-proBNP) in blood serum were determined using a sandwich immunoassay.

Results. Patients with CHF had signs of cardiac remodeling and higher values of NT-proBNP, MMP-2 and MMP-9 (p<0.001) than women from the control group. After 24 months of observation, all patients with CHF were divided into 2 groups: group 1 – women with an unfavorable course of CHF (n = 54), group 2 – women with favorable course of pathology (n = 60). Criteria for the unfavorable course of CHF: the emergence of new or worsening of existing symptoms/signs of heart failure; and/or hospitalization due to HF decompensation; decrease in left ventricular ejection fraction by more than 10%; or an increase in the functional class of CHF by 1 or more. Baseline echocardiographic parameters and NT-proBNP values did not differ in groups 1 and 2. Levels of MMP-2 were higher by 8% (p = 0.017) and MMP-9 by 18.4% (p<0.001) in group 1. In 1 group the level of MMP-2 decreased after 24 months of observation. In group 2 the level of MMP-2 increased by the end of the observation period. MMP-2 levels ≥388.2 pg/ml (sensitivity 46%, specificity 80%; AUC = 0.64; p = 0.013) and MMP-9 ≥21.3 pg/ml (sensitivity 86%, specificity 84.4%; AUC = 0.9; p<0.001) were determined as predictors of an unfavorable course of CHF.

Conclusion. Remodeling of the extracellular matrix may play an important role in the pathogenesis of CHF initiated by drugs of the anthracycline class. Elevated levels of MMP-2 and MMP-9 in the blood serum are associated with an unfavorable course of anthracycline-induced CHF and can be recommended when assessing the risk of an unfavorable course of pathology.
Blood monocytes in maintaining the balance of vascular endothelial injury and repair process in ischemic cardiomyopathy
Authors: Chumakova S. P. , Urazova O. I. , Denisenko O. A. , Pogonchenkova D. A. , Shipulin V. M. , Pryakhin A. S. , Nevskaya K. V. , Gladkovskaya M. V.
Published: October 2022

Highlights. The features of subsets of monocytes in combination with the levels of desquamated endotheliocytes, endothelial damage and regeneration mediators and progenitor cell migration-enhancing factors in patients with coronary heart disease and with/without ischemic cardiomyopathy were analyzed. For the first time it was shown that in patients with ischemic cardiomyopathy, compared with CHD patients without cardiomyopathy, higher desquamation of the endothelium is associated with a deficiency of non-classical monocytes and reduced migration of progenitor endothelial cells (VEGFR2+-monocytes) with regenerative potential across the bone marrow due to a deficiency of the HIF-1α mediator in the blood.

Background. The development of ischemic cardiomyopathy (ICM) is an understudied process, and one of its elements may be insufficient regeneration of blood vessels due to an imbalance of subsets of monocytes in the blood.

Aim. To assess subsets of monocytes and desquamated endothelial cells in combination with endothelial damage and regeneration mediators in the blood of patients with coronary heart disease (CHD) and with/without ICM.

Methods. The study included 30 patients with ICM, 22 patients with coronary heart disease without cardiomyopathy aged 55–69 years, and 18 healthy donors. In whole blood, the populations of CD45–CD146+ desquamated endothelial cells and progenitor endothelial cells related to CD14+VEGFR2+  monocytes, intermediate CD14++CD16+   and  non-classical  CD14+CD16++   monocytes  were  assessed  by flow cytometry  using  the  appropriate  monoclonal  antibodies  (BD  Biosciens, USA). In blood plasma, the levels of hypoxia-inducible factor HIF-1α, monocyte chemoattractant protein MCP-1 and matrix metalloproteinase MMP-9 were assessed by enzyme immunoassay. The results of the analysis were considered significant at p<0.05.

Results. The number of progenitor and desquamated endothelial cells was increased in both groups of patients with coronary artery disease. At the same time, in patients with ICM, the number of progenitor endothelial cells did not reach the number noted in patients with CHD without cardiomyopathy, while the number of desquamated endothelial cells reached the number noted in CHD patients without cardiomyopathy. There was a deficiency of non-classical monocytes and HIF-1α in the blood of patients with ICM, and an excess of intermediate monocytes and MCP-1 was observed in CHD patients without cardiomyopathy. The concentration of MMP-9 in patients with CHD corresponded to the norm, regardless of the presence of ICM.

Conclusion. In ICM, in contrast to CHD without cardiomyopathy, vascular damage is associated with a deficiency of nonclassical monocytes and reduced endothelial repair due to insufficient migration of progenitor endothelial cells across the bone marrow due to HIF-1α deficiency in the blood.
A Method to Generate Initial Fault Stresses for Physics-Based Ground-Motion Prediction Consistent with Regional Seismicity
Authors: Oral Elif , Ampuero Jean Paul , Ruiz Javier , Asimaki Domniki
Published: October 2022

Near-field ground motion is the major blind spot of seismic hazard studies, mainly because of the challenges in accounting for source effects. Initial stress heterogeneity is an important component of physics-based approaches to ground-motion prediction that represents source effects through dynamic earthquake rupture modeling. We hypothesize that stress heterogeneity on a fault primarily originates from past background seismicity. We develop a new method to generate stochastic stress distributions as a superposition of residual stresses left by the previous ruptures that are consistent with regional distributions of earthquake size and hypocentral depth. We validate our method on Mw 7 earthquake models suitable for California by obtaining a satisfactory agreement with empirical earthquake scaling laws and ground-motion prediction equations. To avoid the excessive seismic radiation produced by dynamic models with abrupt arrest at preset rupture borders, we achieve spontaneous rupture arrest by incorporating a growth of fracture energy as a function of hypocentral distance. Our analyses of rupture and ground motion reveal particular signatures of the initial stress heterogeneity: rupture can locally propagate at supershear speed near the highly stressed areas; the position of high-stress and low-stress areas due to initial stress heterogeneity determines how the peak ground-motion amplitudes and polarization spatially vary along the fault, as low-stress areas slow down the rupture and decrease stress drop. We also find that the medium stratification in the fault zone amplifies fault slip and consequent ground motion, which requires understanding the interaction between site effects and rupture dynamics. Our approach advances our understanding of the relations between dynamic features of earthquake ruptures and the statistics of regional seismicity, and our capability to integrate information about regional seismicity into near-field ground-motion prediction.
Pengembangan Media Pembelajaran Pencak Silat Berbasis Aplikasi Android Materi Variasi dan Kombinasi Untuk Siswa Kelas IX SMP Tahfidz Al-Manshurin Kabupaten Malang
Authors: Rosyidi Ali , Heynoek Febrita Paulina , Kurniawan Ari Wibowo , Hariyanto Eko
Published: October 2022

Abstract: Media is one of the factors to encourage students to more easily understand the material in learning activities at school, so that media is needed in learning activities of pencak silat. The purpose of this research is to develop learning media of pencak silat based on android application for learning PJOK for grade 9 students of SMP Tahfidz Al-Manshurin Malang Regency which can be used as a learning medium for students both during school and at home learning and as a means of supporting teachers in providing pencak silat learning. The research method that the writer uses is descriptive quantitative method. Based on the results of the research taken, it shows that the average test carried out by filling out a questionnaire at SMP Tahfidz Al-Manshurin Malang City District is based on 85 percent of students who express more interest in learning pencak silat using Android application-based learning media, and 79 percent of students are more easy to learn in learning in the form of a series of pencak silat movements and balanced game activities. From the results of the analysis of all media variables obtained 79.7 percent it can be concluded that the learning media is in the "good" category or classification, and can be used in SMP Tahfidz Al-Manshurin Malang District.

Abstrak: Media merupakan salah satu faktor untuk mendorong Siswa lebih mudah memahami materi dalam kegiatan pembelajaran di sekolah, sehingga media sangat dibutuhkan dalam kegiatan pembelajaran pencak silat. Tujuan penelitian ini untuk mengembangkan media pembelajaran pencak menggunakan aplikasi android untuk pembelajaran PJOK siswa kelas 9 SMP Tahfidz Al-Manshurin Kabupaten Malang yang dapat dimanfaatkan sebagai media belajar bagi siswa baik saat pembelajaran di sekolah maupun di rumah dan menjadi sarana pendukung guru dalam memberikan pembelajaran pencak silat. Adapun metode penelitian yang digunakan penulis berupa metode deskriptif kuantitatif. Berdasarkan hasil penelitian yang diambil, menunjukkan bahwa rata-rata tes yang dilakukan dengan melakukan pengisian angket di SMP Tahfidz Al-Manshurin Kabupaten Kota Malang berdasarkan 85 persen siswa yang menyatakan lebih tertarik belajar pencak silat menggunakan media pembelajaran berbasis aplikasi android, serta 79 persen siswa lebih mudah belajar dalam pembelajaran menggunakan rangkaian gerak pencak silat dan diimbangi aktivitas bermain. Dari hasil analisis semua variabel media memperoleh 79,7 persen dapat disimpulkan bahwa media pembelajaran berada dalam kategori atau klasifikasi “baik”, dan dapat digunakan di SMP Tahfidz Al-Manshurin Kabupaten Malang.
Pengetahuan dan Subjective Norm untuk Perilaku Seksual Pekerja Usia Muda Kawasan Industri X
Authors: Fatmala Yuliana , Supriyadi Supriyadi , Deniati Ema Novita , Katmawanti Septa
Published: October 2022

Abstract: Adolescence is a time when teenagers looking for an identity and their life. At this time, teenagers tend have a great curiosity about various things, include a sexual behavior. Sexual behavior at a young age in each individual is different. This sexual behavior was influenced by knowledge and subjective norms. The aims of this research were (1) to see there is an influence of knowledge on sexual behavior in young workers, (2) to see there is an influence of subjective norms on sexual behavior in young workers, and (3) to see there is a simultaneous effect between knowledge and subjective norms on sexual behavior in young workers. The method of this research used was a quantitative method with an explanatory research approach. This research sample’s used were 322 respondents with a significance level of 5 percent. The data collection technique used was a questionnaire. The results shows were (1) the knowledge aspect has a t-test value of 8.2124 which indicates an influence of knowledge on sexual behavior, (2) subjective norm has a t-test value of 7.540 which indicates an influence of subjective norms on sexual behavior, and (3) the test value f of 132,333 which indicated that knowledge and subjective norms had a simultaneous influence on sexual behavior.

Abstrak: Masa remaja merupakan masa dimana para remaja melakukan pencarian jati diri dan makna hidup. Remaja pada tahap ini cenderung sangat ingin tahu tentang berbagai hal, termasuk perilaku seksual. Perilaku seksual di usia muda pada setiap individu berbeda-beda. Perilaku seksual ini diantaranya dipengaruhi oleh pengetahuan dan subjective norm. Tujuan dari penelitian ini adalah (1) untuk melihat ada tidaknya pengaruh pengetahuan terhadap perilaku seksual pada pekerja usia muda, (2) untuk melihat ada tidaknya pengaruh subjective norm terhadap perilaku seksual pada pekerja usia muda, dan (3) untuk melihat ada tidaknya pengaruh secara simultan antara pengetahuan dan subjective norm terhadap perilaku seksual pada pekerja usia muda. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan pendekatan explanatory research. Sampel yang digunakan sebanyak 322 orang dengan taraf signifikansi 5 percent. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah kuesioner. Hasil penelitian menunjukkan (1) aspek pengetahuan mempunyai nilai uji t sebesar 8.2124 yang menunjukkan adanya pengaruh pengetahuan terhadap perilaku seksual, (2) subjective norm mempunyai nilai uji t sebesar 7.540 yang menunjukkan adanya pengaruh subjective norm terhadap perilaku seksual, dan (3) nilai uji f  sebesar 132.333 yang menunjukkan bahwa pengetahuan dan subjective norm memberikan pengaruh secara simultan terhadap perilaku seksual.
Pembelajaran Daring PJOK di MTsN 2 Kota Malang
Authors: Armidianta Hafidh Praga , Winarno Mashuri Eko , Wiguno Lokananta Teguh Hari , Nurrochmah Siti
Published: October 2022

Abstract: The formulation of the research problem is whether students at MTsN 2 Malang City are able to implement the PJOK learning model through online. This research is a quantitative descriptive study using a survey method, with a total sample of 98 students at MTsN 2 Malang City. The instrument used is in the form of a questionnaire or questionnaire that has been validated by the supervisor. Analysis of research data using descriptive statistical analysis method. The research results show that (1) the readiness of the institution 79 percent, good category. (2) organizational dimensions 78 percent, good category. (3) learning materials 80 percent, good category. The average number that gets a percentage value is 79 percent and if it is classified it is in the good category. The conclusion is that the implementation PJOK learning model at MTsN 2 Malang City through online learning has implemented learning that can help students and students in teaching and learning activities for PJOK learning well.

Abstrak: Rumusan masalah dalam penelitian ini yaitu apakah siswa di MTsN 2 Kota Malang mampu melaksanakan model pembelajaran PJOK melalui daring. Jenis penelitian adalah deskriptif kuantitatif menggunakan metode survei, dengan jumlah sampel sebanyak 98 siswa di MTsN 2 Kota Malang. Instrumen yang digunakan berbentuk angket atau kuesioner yang telah divalidasi oleh pembimbing. Analisis data penelitian menggunakan metode analisis statistik deskriptif. Hasil riset memaparkan bahwa (1) kesiapan lembaga sebesar 79 persen, dalam kategori baik. (2) dimensi organisasi 78 persen, dalam kategori baik. (3) materi pembelajaran sebesar 80 persen, dalam kategori baik. Jumlah rata-rata dari keseluruhan riset didapatkan nilai persentase sebesar 79 persen dan jika diklasifikasikan maka termasuk dalam kategori baik. Dapat disimpulkan bahwa model pembelajaran PJOK di MTsN 2 Kota Malang melalui pembelajaran daring telah menerapkan pembelajaran yang dapat membantu para siswa dan siswi dalam kegiatan belajar mengajar pembelajaran PJOK dengan baik.
Retracted: Pengembangan Latihan Imagery Untuk Meningkatkan Kepercayaan Diri pada Atlet Renang Usia Remaja di Garuda Aquatic Swimming Club Kabupaten Kediri
Authors: Sabilla Nadya Putri , Rahayuni Kurniati , Hanief Yulingga Nanda , Supriatna Supriatna
Published: October 2022

This paper has been withdrawn at the request of the author and has been retracted.
UAV fully-actuated: modelo, control y comparación con configuración coplanaria
Authors: González-Morgado Antonio , Álvarez-Cía Carlos , Heredia Benot José Guillermo , Ollero Baturone Aníbal
Published: October 2022

Con el desarrollo de la robótica aérea han aparecido nuevas plataformas de multirotores de actuación completa (fully-actuated en inglés), las cuales tienen la capacidad de desplazarse sin inclinar la plataforma. Este artículo presenta una comparación en cuanto a capacidades de movimiento entre un hexarotor de rotores coplanarios, configuración estándar, y un hexarotor de rotores inclinados, configuración fully-actuated. Para ello, se presenta el diseño, modelo y control de ambas configuraciones. Tras el montaje de las plataformas, se comparan con diferentes trayectorias. Así mismo, se muestran capacidades exclusivas de la plataforma fully-actuated, como la capacidad de mantenerse en hover con un ángulo de inclinación
Diseño de una articulación de dos grados de libertad para robots modulares
Authors: Mena Lisbeth , Gil Daniel , Monje Concepción A. , Martinez Santiago , Balaguer Carlos
Published: October 2022

Los robots modulares tienen como principal característica la reconfiguración de su estructura, adoptando diferentes morfologías, lo que es posible gracias a la unión articular de los módulos que los componen. Con esta intención, este artículo propone el diseño de una articulación de 2 Grados de Libertad (GDL) que permita la conexión de eslabones modulares basados en estructuras de origami blandas.
Solución de la planificación de movimientos de un robot móvil paralelo binario mediante cinemática inversa de un robot hiper-redundante equivalente
Authors: Pérez-Checa Mario , Peidró Adrián , Jiménez Luis Miguel , Payá Luis , Reinoso Óscar
Published: October 2022

Este artículo presenta la resolución de la planificación de movimientos de un robot móvil paralelo y binario, determinando la secuencia de movimientos discretos necesarios para alcanzar cualquier posición final deseada. Este problema se reformula y resuelve como la cinemática inversa de un manipulador híper-redundante equivalente, formado por concatenación de tantos módulos binarios como posiciones intermedias debe ocupar el robot móvil a lo largo de su trayectoria. Esta reformulación permite aplicar eficientes técnicas de resolución de cinemática inversa de robots binarios híperredundantes, resolviendo el problema con gran precisión, evitando métodos de fuerza bruta por enumeración exhaustiva que resultan imprácticos por requerir excesivos tiempos de cómputo y recursos de memoria. Se incluyen varios ejemplos en simulación para demostrar la validez y eficiencia del método de cálculo, que además puede aplicarse en tiempo real.
Upscaling in socio-environmental systems modelling: Current challenges, promising strategies and insights from ecology
Authors: Dressler Gunnar , Groeneveld Jürgen , Hetzer Jessica , Janischewski Anja , Nolzen Henning , Rödig Edna , Schwarz Nina , Taubert Franziska , Thober Jule , Will Meike , Williams Tim , Wirth Stephen Björn , Müller Birgit
Published: October 2022

Sustainability challenges in socio-environmental systems (SES) are inherently multiscale, with global-level changes emerging from socio-environmental processes that operate across different spatial, temporal, and organisational scales. Models of SES therefore need to incorporate multiple scales, which requires sound methodologies for transferring information between scales. Due to the increasing global connectivity of SES, upscaling – increasing the extent or decreasing the resolution of a modelling study – is becoming progressively more important. However, upscaling in SES models has received less attention than in other fields (e.g., ecology or hydrology) and therefore remains a pressing challenge. To advance the understanding of upscaling in SES, we take three steps. First, we review existing upscaling approaches in SES as well as other disciplines. Second, we identify four main challenges that are particularly relevant to upscaling in SES: 1) heterogeneity, 2) interactions, 3) learning and adaptation, and 4) emergent phenomena. Third, we present an approach that facilitates the transfer of existing upscaling methods to SES, using two good practice examples from ecology. To describe and compare these methods, we propose a scheme of five general upscaling strategies. This scheme builds upon and unifies existing schemes and provides a standardised way to classify and represent existing as well as new upscaling methods. We demonstrate how the scheme can help to transparently present upscaling methods and uncover scaling assumptions, as well as to identify limits for the transfer of upscaling methods. We finish by pointing out research avenues on upscaling in SES to address the identified upscaling challenges.
Drought Indices to Map Forest Fire Risks in Topographically Complex Mountain Landscapes
Authors: Sari Astuti Ike , Abdul Gani Alfarizi Imam , Aulia Herlambang Gilang , Aulia Herlambang Gilang , Hartono Rudi , Rahmawati Sucahyo Hetty , Setiabudi Wiwoho Bagus
Published: October 2022

Drought has the potential to lead to forest fires. Forest fires generally occur during the dry season when the mountain slope forest experiences a water deficit. Drought identification based on remote sensing is useful for mapping potential fires in Arjuno- Welirang Forest and TNBTS Forest (in Bromo Tengger Semeru National Park). This research used Landsat-8 images in 118/065 and 118/066 in August and November 2015-2018. Validation data were obtained using high resolution planet scope images and rainfall data. Three drought indices were tested to identify fires, namely TVDI, VHI and NDDI. The indices were tested visually using high resolution images and tested meteorologically using SPI. From the results of the accuracy test and correlation, TVDI had the highest accuracy in the Arjuno-Welirang forest (96% accurate), while the best index for TNBTS was the VHI index (96% accurate).
Keywords: drought indices, TVDI, VHI, NDDI, forest fires, Indonesia
Landslide Susceptibility Assessment in Mojokerto Regency Using Logistic Regression
Authors: Y Irawan L , Panoto D , Hartono R , H Pradana I , Darmansyah A C
Published: October 2022

The impact of landslides varies from place to place, including cutting off transportation routes, destroying agricultural land, and/or destroying houses. Due to the high threat of landslides, it is necessary to make efforts to improve community preparedness by disseminating information about landslide distribution. In this research, landslide assessment was conducted using logistic regression. Twelve landslide factors were assessed including topographic position index, stream power index, slope, aspect, elevation, profile curvature, distance to drainage, soil, rainfall, land use, and distance to road. The assessment of the landslide susceptibility level in this study was highly accurate, based on the AUC value obtained, which was 0.92. The results of the assessment of the landslide susceptibility level were divided into five classes with the following areas: very low 36%, low 4.4%, moderate 2.91%, high 4.1% and very high 52.5%.
Keywords: scientific, approach, methodological, techniques, geography
Geography Virtual Reality for Learning About Ecotourism and Rural Sustainability
Authors: Kurnia Putra Alfyananda , Naufal Islam Muhammad , Hilmi Robby , Khairunisa Tasya , Arifa'illah Syaiful Huda Imam
Published: October 2022

Tourism has an essential role in economic development through improving people’s welfare. However, tourism activities are vulnerable to global issues, one of which is the COVID-19 pandemic. Social restrictions on economic activity have implications for the sustainability of tourism. One effective strategy to maintain tourism sustainability in regional development can be achieved through education channels by packaging the concept of tourism into virtual reality (VR) 3600-assisted learning materials. This study aimed to develop VR 360∘ media in supporting geography learning on sustainable ecotourism. This was development research using the PLOMP model, which consisted of 3 stages: (1) preliminary research; (2) prototype design and development; and (3) evaluation. The results showed that the VR 3600 media helped the student’s learning process actively and independently through interaction with 3600 panoramic projections and multimedia. Immersive learning experiences involving complex thinking and contextual reflection were formed through the VR 360∘-assisted learning activities with learning outcomes of a) information literacy, b) exploration, and c) reflection on the content of sustainable ecotourism. Learning activities engaged through the virtual environment are expected to foster a good understanding in the student environment of the importance of managing and developing ecotourism in supporting rural sustainability.
Keywords: mobile immersive, geography, virtual reality 360∘, ecotourism, rural sustainability
Phenomenon of Unregistered Marriage in Teenagers in Indonesia: A Case Study of the Madurese Community in Situbondo
Authors: Susilo Singgih , B Budijanto , Definika Ifan , Definika Ifan
Published: October 2022

Unregistered marriage (‘sirri marriage’) is widespread in Indonesian society, and this social phenomenon can be considered a form of disharmony in society. Even though sirri marriages have a negative impact, especially for women and children, they are still commonly found in Indonesia, including in Situbondo Regency, East Java. This study used a phenomenological approach. The research subjects were fifteen teenage girls who were married by unregistered marriage in Situbondo Regency. The research was conducted through interviews and observations. The data were analyzed using qualitative techniques. The results demonstrated that unregistered marriage was interpreted as an effort to avoid sin, as certainty in a relationship, and as an economic solution. Unregistered marriages, with the perception of cultural and religious legitimacy, which are often early marriages, have implications for the development of the family. One of the consequences of an early marriage is that the young couple is still totally dependent on their parents. These early unregistered marriages force children to drop out of school and become underage workers. Unregistered marriages also lead to divorce, and divorce rates are soaring. Divorce occurs because the young couple is not ready to manage conflicts in the household due to immaturity.
Keywords: unregistered marriage, phenomenology, teenagers, economy
Application of Cultural Tourism Using Community-Based Tourism in the Kayutangan Heritage Area of Malang City
Authors: Deffinika Ifan , Regina Heni Prastiwi Mellinia , Arinta Dicky
Published: October 2022

The Kayutangan heritage area still maintains the architectural forms from its Dutch colonial heritage. The attractions of this form include: cultural heritage buildings, burial sites, irrigation canals and tunnels, the krempyeng market, and events. The purpose of this research was to describe and analyze the application and impact of cultural tourism with the community-based tourism (CBT) concept in the Kampoeng Kayutangan heritage area in Malang City. A descriptive qualitative approach was used to analyze the factors of sustainable tourism development. The results showed that the existing application in the area, covering economic, social, cultural, environmental and political aspects, is already based on the CBT concept. In the economic dimension, the source of funds comes from ticketing or donations allocated for tourism development. However, the economic impact of this tourism has been limited because the impact has not been achieved by the people themselves. In the social dimension, tourists are warmly welcomed when visiting this tourist attraction, which upholds a spirit of togetherness and kinship in serving guests. In the cultural dimension, there is an exchange of ideas where the idea will be accepted and applied for better tourism development. In the environmental dimension, the existing management in this area has not yet implemented 3R, but the management applies segregation and the existing sanitation system is good. In the political dimension, decision-making regarding tourism in this area is carried out by the local tourism community in the Kayutangan Heritage’s Pokdarwis (Tourism Awareness Group).
Keywords: cultural tourism, community-based tourism, Kayutangan Heritage, Malang City 1.
Speaking of Online Learning: Alternative Practice-Based Learning Experiences for Speech Pathologists in Australia, Ghana and Hong Kong
Authors: Skeat Jemma , Bampoe Josephine Ohenewa , Booth Susan , Brogan Emily , Conway Maya , Davenport Rachel , Howells Simone , Kan Peggy , Krahe Michelle , Hewat Sally , Lewis Abigail , Little Alex , Walters Joanne , Webb Gwendalyn , Worthington Nikki
Published: October 2022

Speech Pathology programs usually send students to workplaces to learn clinical skills necessary for practice. During COVID-19, programs needed to respond quickly to ensure that students continued to gain the necessary experiences and skills required to progress through their program and graduate as clinicians, while simultaneously complying with COVID-19 requirements. Case studies from seven different universities in Australia, Ghana and Hong Kong described the diverse ways in which placements were adapted to be COVID-safe, taking into account local needs. Some practices which had been included in placement education prior to the pandemic, such as telepractice and simulation-based learning, were extended and developed during this time. Educators, students, clinicians and clients responded to the rapidly changing needs of the time with flexibility and innovation, utilising a variety of technologies and tools to support case-based and virtual learning opportunities. Feedback from these diverse stakeholders about the experiences was positive, despite inevitable limitations and less-than-ideal circumstances.  The positive findings provided insights for consideration in the future: could strategies implemented in response to the pandemic continue to be incorporated into placement experiences, enhancing current practices and maintaining student performance outcomes? Exceptional circumstances prompted exceptional responses; flexibility and innovation were accelerated in response to the pandemic and may transform future placement-based learning opportunities.
Congruence de deux théories polyphoniques dans l’analyse stylistique des textes romanesques : intertextualité et dialogisme dans L’état z’héros ou la guerre des gaous de Maurice Bandaman
Authors: Coulibaly Daouda
Published: October 2022

L’état z’héros est une œuvre dans laquelle Maurice Bandaman intègre le conte dans la structure du roman. Sa discursivité repose sur un certain nombre d’intertextes oraux dont les chants rituels, les stances, les opus et des références intégrées sous la forme d’un collage littéraire. Au niveau de la narration, la voix des narrateurs interagit avec celles des personnages dans les dialogues et les monologues autonomes des personnages ou des narrateurs. Ces relations dialogiques mettent en relief des métalepses narratives qui ressortent de la polyphonie. Celle-ci est l’une des marques de la littérarité, principal moteur de l’analyse stylistique. À travers un double objectif, primo, il s’agit de montrer que le dialogisme et l’intertextualité sont deux approches qui se font écho dans l’analyse stylistique des textes romanesques, en l’occurrence de ce texte de Maurice Bandaman. Secondo, il est question de prouver que les relations intertextuelles débouchent sur la polyphonie et mettent au premier plan la littérarité.
Je devenais une goutte d’eau, une tache d’encre. Sulla narrativa di Maurice Blanchot
Authors: Crivella Giuseppe
Published: October 2022

Partendo da una serie di analisi contenute nell’opera di Philippe Hamon Rencontres sur tables et choses qui traînent. De la nature morte en littérature, questo saggio punta a sviluppare alcune considerazioni aventi per oggetto la produzione narrativa di Maurice Blanchot. In particolare le nostre osservazioni si concentreranno su alcuni passaggi desunti da tre romanzi del pensatore francese: Aminadab, La folie du jour e Le Très-Haut. In tal modo potremo mettere a punto una prospettiva interpretativa dei récits blanchotiani in cui la nozione di natura morta gioca un ruolo di assoluta centralità. In particolare le nostre analisi si concentreranno sul modo in cui la nozione di natura morta riesce a tramutarsi in un terminale ermeneutico trasversale in seno al quale numerosi elementi specifici e ricorrenti degli universi narrativi di Blanchot trovano una precisa collocazione funzionale e una chiara delineazione concettuale. In seconda battuta, le corrispondenze enucleabili tra il narratore francese e il teorico del descrittivo ci permetteranno di portare in evidenza in sede di conclusioni un ricco plesso di temi e questioni che non solo solcano in profondità la narrativa blanchotiana, ma di fatto possono essere reperiti con una certa facilità presso numerosi autori della letteratura francese del secondo Novecento.
Méandres de la maternalité dans Tenir jusqu’à l’aube de Carole Fives et Ida n’existe pas d’Adeline Fleury
Authors: Loska Agnieszka
Published: October 2022

La maternalité, d’après Hyvrard, s’intéresse non seulement à l’enfantement, mais en particulier à tout l’univers mental de la mère et aux changements physiques, psychiques, sociaux et culturels dans sa vie. Le présent article montre ces changements et analyse l’ambiguïté des émotions de deux mères célibataires, protagonistes de Tenir jusqu’à l’aube (2018) de Carole Fives et d’Ida n’existe pas (2020) d’Adeline Fleury. S’appuyant sur les théories féministes (Kristeva, Irigaray) et psychanalytiques (Guéritault), il démontre qu’à l’origine de leurs émotions négatives et de leur refoulement de la maternité se trouve le burn-out maternel. La complexité de ce sentiment, qui résulte à la fois de la fonction maternelle et de la situation particulière des mères en question, se manifeste, entre autres, par leur dépersonnalisation, leur isolement et leurs émotions contradictoires envers l’enfant.
Digitalization, knowledge sharing and higher education for sustainable development
Authors: Li Ming , Jotikasthira Nuttapong , Pu Ruihui
Published: October 2022

This academic paper focuses on digitalization and higher education for sustainable development (HESD). A systemic review of 67 articles published in Web of Science (WOS) in the past decade was undertaken. The articles were chosen because of their relevance to this era of digitalization and the role of higher education in promoting knowledge sharing with respect to sustainable development. The analysis used six categories: journals, publication year, research design, industry sectors, topics, and opportunities and challenges. However, there is lack in exploring the recent trends, possible application industries and the essence of HESD in the context of digitalization and knowledge sharing in different regions of the world. The main aim of this article is to report on a meta-analysis consisting of a systematic review of the available literature related to digitalization and knowledge sharing. The study revealed that current research on sustainable development lack mathematical models and empirical tools.
Keywords: Digital age; Digital higher education; Higher education for sustainable development; Knowledge sharing; Sustainable practices,