bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcultural adaptation and psychometric properties of the Spanish version of Participation and Environment Measurement - Children and Youth (PEM-CY)
Authors: Gómez-Vela María , Baz Mª Begoña Orgaz , Vicario-Molina Isabel , Ortega Eva González , Corbella Marta Badia
Published: February 2025

Background
The Participation and Environment Measure for Children and Youth (PEM-CY) captures a child’s participation across home, school, and community-based activities as well as environmental factors perceived as supporting/hindering this participation. This tool has been translated into Spanish for use in the United States and Colombia but there are linguistic and sociocultural differences between these countries and Spain. Therefore, it is necessary to develop a country-specific measure to promote environment-based interventions for Spanish children with disabilities. This study aims to adapt the PEM-CY for use with children and youth in Spain, and to investigate its psychometric properties.
Methods
713 parents of children with (n = 233) and without (n = 480) disabilities, aged 5 to 17, completed the Spanish version of PEM-CY. For the test–retest reliability study, 30 of these parents completed the instrument twice.
Results
Internal consistency (0.58–0.97) and test–retest reliability (0.31–0.92) ranged from moderate to very satisfactory, according to Cronbach’s alpha and intraclass correlation coefficients. Discriminant validity, assessed through two-way ANOVA, was supported by significant differences between children with and without disabilities on participation and environment scales (p < .05). Some significant age differences were identified for participation at home and school. Validity was supported by a significant negative Pearson’s correlation (-0.32 to -0.41, p < .05) between desire for change and overall environmental supports.
Conclusions
The Spanish version of the PEM-CY is a valid and reliable tool to determine the participation and associated environmental factors in Spanish children and youth, with and without disabilities. It provides useful information for designing environment-based interventions to promote their participation.
Impact of Food Advertising Restrictions in Portugal on Children’s Exposure to Unhealthy Foods and Beverages: A Before-and-After Study
Authors: Royo-Bordonada Miguel Ángel , Cavero-Esponera Cristina , Romero-Fernández María Mar
Published: February 2025

Background
Portugal has one of the highest prevalences of childhood obesity in the world. Food advertising, which largely affects the most vulnerable children, contributes to childhood obesity by fostering the consumption of ultra-processed foods and beverages. To prevent this pernicious influence, Portugal passed Act 30/2019 which introduces food advertising restrictions targeted at children and adolescents under 16 years of age. The aim of this study was to assess the Act’s effectiveness in reducing the exposure of children and adolescents under14 years of age to television advertising of unhealthy foods and beverages.
Methods
We conducted a before-and-after study by measuring the impact of food sector television advertising over the course of two, week-long periods, the first in February 2019 and the second in February 2022. The respective samples included 1121 and 983 children and adolescents aged 4 to 14 years, representative of the Portuguese population in this age range. The nutritional quality of the products advertised was analysed using the nutritional profile issued by the Directorate-General of Health. Before-and-after mean impacts and coverages were compared, using the Chi-squared test to analyse differences in the latter.
Results
The weekly mean impacts of unhealthy food and beverage advertisements remained stable from 2019 to 2022 (18.9 vs. 18.7). Even so, impacts decreased in the case of low-class children and increased in the case of middle and high-class children. While overall coverage did not vary, it decreased in the morning and afternoon time slots, and increased across the night time slot. As compared to 2019, the weekly number of unhealthy food and beverage commercials increased by 25% in 2022.
Conclusions
Act 30/2019 did not reduce Portuguese children’s overall exposure to advertisements for unhealthy foods and beverages. In order to be effective, restrictions would, at minimum, have to cover television advertising during the 7 am-12 pm time band, regardless of the intended recipients of the messages, target public or percentage of children’s audience.
Boron’s Role in B16-F10 Melanoma: Cytotoxic, Antioxidant, Apoptotic, and Anti-inflammatory Effects
Authors: varol mehmet , Subasi Bugra , Koldemir-Gündüz Meliha , Yerlikaya Azmi
Published: February 2025

Aim Malignant melanoma is a fatal cancer type with a high risk of metastasis. Despite traditional treatments, the survival time of patients is usually 3–9 months. Therefore, new treatment strategies are needed. The aim of this study was to examine the potential role of boric acid in the treatment of melanoma through the evaluation of the cytotoxic, oxidative stress, anti-inflammatory, apoptotic effects of boric acid on B16-F10 mouse melanoma cell line.Method The cytotoxic effect was determined using the MTT method. TNF-α, IL-6, Bax, Bcl-2, and p53 gene expressions were determined with qPCR. MDA, GSH levels, and CAT activity were measured with a spectrophotometric method. The ELISA method was used for the evaluation of TNF-α, IL-1β, IL-6, IL-10, annexin-V, and Bcl-2 levels. Giemsa staining was used in the histological examinations.Results The results demonstrated that boron treatment induced dose-dependent apoptosis by reducing cell viability, compared to the untreated control cells. In the cells treated with boron, while Bcl-2 gene expression was decreased, the expression of Bax, p53 gene expressions and the level of annexin-V was increased. It was also seen that TNF-α and IL-6 mRNA expression levels and IL-1β and IL-10 levels were decreased in the cells treated with boron. Following boron treatment, an increase in CAT activity, as well as higher levels of GSH and MDA, was observed.Conclusion Boron could be effective in the treatment of melanoma through creating oxidative stress, decreasing TNF-α and IL-6 levels. This compound can be evaluated as a promising cancer treatment agent.Level of Evidence: 5
المجموعة الثانية من الألفاظ الكردية المعربة في القرآن الكريم –دراسة تحليلية- الجودي
Authors: Qader Faiz Abubakir
Published: February 2025

إن مسألة الكلمات المعرَّبة ووجودها في كلام الله تعالى هي مسألة تناولها العلماء المعنيون بعد وقت قصير من نزول الوحي، بين من ينكرها وبين من لا يرى في وجودها ضررا. بالإضافة إلى ذلك، يرى فريق أن وجود الكلمات المعربة هو معجزة قرآنية عظيمة. وقد تناول البحث هذا الأمر، وتناول أيضاً الحكمة من وجود الكلمات المعربة من اللغة الكردية في القرآن الكريم وفوائد وجود تلك الكلمات. اضافة الى ما سبق يتناول البحث موضوع وجود الكلمات المعربة في اللغة الكردية وهو موضوع لم يتم التطرق اليه ولم يشر اليه احد رغم وجود العديد من العوامل المؤثرة منها علاقة حسن الجوار. ويتولد منها الاتصال والاحتكاك، وهذه العلاقة قديمة بين العرب والأكراد. ويدل على ذلك رثاء مالك بن الريب الشهير المتوفى سنة 56 هـ. تعتبر اللغة الكردية من أولى اللغات التي عرفها العرب وأخذوا منها كلمات كردية بحتة، وذلك لوجود علاقة تأثير بين اللغة الكردية والعربية سلباً وإيجاباً. والكلمات المعربة من الكردية التي تناولها البحث هي: 1. الجودي، -2 السجيل، -3 السرابيل.
ڕۆڵی پڕۆژه‌ی ڕاهێنانی وه‌زاره‌تی په‌روه‌رده‌‌ له‌ ده‌ستخستنی كارامه‌ییه‌ بنچینه‌ییه‌كانی وانه‌وتنه‌وه‌ لای مامۆستایانی قۆناغی بنه‌ڕه‌تی
Authors: Aram Issa Mirza  , Rahbar Masood Abdulkhaleq  , Azeez Saeed Azeez
Published: February 2025

پوخت
   ئه‌م توێژینه‌وه‌یه‌ ئه‌نجامدراوه‌ به ‌مه‌به‌ستی زانینی ڕۆڵی پڕۆژه‌ی ڕاهێنانی وه‌زاره‌تی په‌روه‌رده‌ له‌ ده‌ستخستنی كارامه‌ییه‌ بنچینه‌ییه‌كانی وانه‌وتنه‌وه‌ لای مامۆستایانی قۆناغی بنه‌ڕه‌تی، و ده‌رخستنی جیاوازییه‌كان به‌پێی گۆڕاوه‌كانی (ڕه‌گه‌ز، ساڵانی خزمه‌ت و پسپۆری). توێژه‌ران ڕێبازی وه‌سفی شیكارییان به‌كارهێناوه‌. كۆمه‌ڵگه‌ی توێژینه‌وه‌كه‌ بریتیبوو له‌ سه‌رجه‌م مامۆستایانی بازنه‌ی دووه‌م له‌ په‌روه‌رده‌ی ناوه‌ندی هه‌ولێر بۆ ساڵی خوێندنی (2023-2024). توێژه‌ران بۆ به‌ده‌ستهێنانی ئامانجه‌كه‌یان، پێوه‌ری ڕاهێنانی كارامه‌ییه‌ بنچینه‌ییه‌كانی وانه‌وتنه‌وه‌یان بنیاتنا به‌پێی بنه‌ماكانی پیوانه‌ و هه‌ڵسه‌نگاندنی په‌روه‌رده‌یی‌، دوای دڵنیابوونه‌وه‌ له‌ جێگیری پێوه‌ره‌كه‌، پیوه‌ره‌كه‌ جێبه‌جێكرا له‌سه‌ر نموونه‌ی سه‌ره‌كی توێژینه‌وه‌كه‌، كه‌ پێكهاتبوو له‌ (150) مامۆستا له‌ هه‌ردوو ڕه‌گه‌ز. دوای كۆكردنه‌وه‌ی داتاكان، ڕێكخستن و شیكردنه‌وه‌یان به‌ هه‌گبه‌ی ئاماری (SPSS) توێژه‌ران گه‌یشتنه‌ ئه‌م ئه‌نجامانه‌:
1– پرۆژه‌ی ڕاهێنانی وه‌زاره‌تی په‌روه‌رده‌ ڕۆڵێكی ئه‌رێنی هه‌بووه‌ له‌ ده‌ستخستنی كارامه‌ییه‌ بنچینه‌ییه‌كانی وانه‌وتنه‌وه‌ لای مامۆستایان به‌ ڕێژه‌ی سه‌دی (78%) و ئاستی (ناوه‌ند).
2- جیاوازی به‌ڵگه‌داری ئاماری هه‌بوو له‌ ئاستی (0.05) له‌ نێوان ڕه‌گه‌زی (نێر و مێ)، له‌ به‌رژه‌وه‌ندی ڕه‌گه‌زی نێر.
3- جیاوازی به‌ڵگه‌داری ئاماری هه‌بووه‌‌ له‌ ئاستی (0.05) له‌ نێوان چینه‌كانی ساڵانی خزمه‌ت، جیاوازییه‌كه‌ش به‌زۆری له‌ نێوان چینه‌كانی (كه‌متر له‌ 15، و زیاتر له‌ 22) ده‌ركه‌وتبوو.
4- جیاوازی به‌ڵگه‌داری ئاماری نه‌بوو‌ له‌ ئاستی (0.05) له‌ نێوان  پسپۆری (كۆمه‌ڵایه‌تی، زانست).
Planning and Strategic Tools for Adapting Urban Areas to Climate Change in Poland
Authors: PANCEWICZ Alina
Published: February 2025

Shaping the development policy of states, regions and cities, referring to broadly understood issues related to the climate change adaptation process, is connected with the necessity of creating new and constantly updated planning and strategic documents and adjusting their provisions to the current needs, global civilisation processes and challenges as well as regional and local specifics. One of the important elements of the adaptation policy is to take into account the problem of urbanised areas adaptation to climate change and management of the built and natural environment resources. The subject of this paper are the planning and strategic tools used in development policy to adapt urbanised areas to climate change. The aim is to indicate the possibilities and limitations of planning instruments in the context of adaptation to climate change and to indicate their coherence in the context of implementation activities. The research includes the planning and strategic instruments developed in the area of sustainable management of the built and natural environment in recent years in Poland, with particular reference to the example of the Metropolis GZM.
Numerical Study of Conditions on the Staircase During a Fire in a Public Building
Authors: SZULC Karolina
Published: February 2025

Fire is one of the most common risks to the environment and human health. Fire, depending on the conditions of combustion and the type of fuel, can emit many toxic products. The paper presents numerical analyzes of the conditions that can occur in a building during a fire. The conditions were analyzed in terms of the safety of the occupants and possible emissions of pollutants into the atmosphere. The temperature, propagation of smoke, and emission of pollutants were analyzed. A numerical model was created using Fire Dynamics Simulator (FDS) software. The model represents a staircase and a corridor in a real building located at the Silesian University of Technology in Poland. The results show that safe conditions are only ensured for a limited time, and emissions can also be harmful to occupants and the environment.
Comércio Internacional na Perspectiva do Islamismo Xiita no Irã
Authors: Beppu Andreia , Racy Joaquim
Published: February 2025

A partir de uma análise bibliográfica e entrevistas realizadas no Irã, este artigo apresenta um debate sobre a visão do Islã para as relações econômicas internacionais, A partir de uma análise bibliográfica e de entrevistas realizadas no Irã, este artigo apresenta a perspectiva do Islã xiita sobre as relações econômicas internacionais, com um enfoque específico na realidade iraniana. O objetivo é debater o pensamento econômico no contexto do comércio internacional, destacando as questões éticas e morais que delimitam o comércio exterior no Islã e como essas questões podem ser consideradas tanto no âmbito da OMC quanto nas relações bilaterais entre países islâmicos e não islâmicos. Além disso, o artigo examina como esses países têm utilizado áreas de Zona Franca e o regionalismo para desenvolver o comércio internacional.precisamente sob um enfoque iraniano. A proposta é debater o pensamento econômico no contexto do comércio internacional, apresentando as questões éticas e morais que delimitam o comércio exterior do Islã e como estas podem ser consideradas tanto no âmbito da OMC, como nas relações bilaterais entre países islâmicos e não-islâmicos, e como esses países têm usado a área de Zona Franca, assim como o regionalismo, para desenvolver o comércio internacional.
Kelulut stingless bee honey stored under different thermal conditions: Non-destructive assessment
Authors: Chin Yee Mun , Saleena Lejaniya Abdul Kalam , Lim Lee Ying , Pui Liew Phing , Solihin Mahmud Iwan
Published: February 2025

Kelulut honey (Heterotrigona itama) is gaining popularity, which makes its quality assessment an important issue. We employed the method of near-infrared spectroscopy to perform a non-destructive quality assessment of refrigerated and non-refrigerated postharvest Kelulut honey. The research objective was to define the physical and chemical properties of Kelulut honey stored for 0, 1, 2, 7, and 14 days, as well as to establish effective prediction models based on the methods of principal component regression and partial least squares.
The Brix value, moisture content, and sugar content exhibited no significant differences (p > 0.05) for the entire storage time. However, the Brix value and sugar content decreased as the moisture increased during storage. pH values decreased while the hydroxymethylfurfural content increased across the entire storage time. Significant differences (p > 0.05) were observed between the pH and hydroxymethylfurfural values for honey stored at different temperatures. The prediction model of sugar content based on principal component regression demonstrated acceptable accuracy (R2 = 0.7) and low mean squared error. After pre-processing and partial least squares regression, the method of near-infrared spectroscopy proved accurate and effective in defining the quality of Kelulut honey.
Functional attributes and bio-prospects of fruit peel waste
Authors: Himanshu Himanshu , Kumar Nishant , Khangwal Ishu
Published: February 2025

The fruit processing industry generates a considerable amount of waste, which leads to significant nutritional and economic losses. The most common waste materials include pomace, peels, rind, and seeds. They contain valuable natural bioactive compounds, such as carotenoids, polysaccharides, dietary fibers, enzymes, polyphenols, oils, and vitamins. These compounds can be recovered by using suitable conventional or non-conventional methods. Conventional methods include Soxhlet extraction, hydro-distillation, and maceration. Non-conventional methods include enzyme-assisted, ultrasound-assisted, microwave-assisted, solid-liquid, and solvent extractions, as well as pulsed electric field. Fruit peels can be used to synthesize metallic nanoparticles, edible packaging, single-cell proteins, biosorbents, biochar, carbon dots, and biofertilizers. Furthermore, their bioactive compounds have a significant pharmacological potential. In particular, they can be utilized as antioxidant, anti-inflammatory, antimicrobial, antiviral, and anti-neoplastic agents.
Fruit peels are also a cost-effective solution that can mitigate various environmental problems and aid in reducing nutritional loss. In this article, we reviewed different extraction techniques employed to retrieve bioactive compounds from fruit peel waste, along with their industrial, biotechnological, and pharmacological applications.
Strategic Approaches to IT Sector Development in the Russian Federation
Authors: Pankratov Aleksey , Musaev Rasul
Published: February 2025

The domestic IT sector needs new strategic approaches to form the national technological foundation for the Russian IT industry that would fulfil the tasks of national security, import substitution, and technological sovereignty. The authors analyzed federal documents on strategic planning that control the Russian IT sector. The industrial disunity of these documents proved to be a major problem: it resulted in a segmented approach to supporting the IT development. The current instruments of state support are governed by the stimulating approach to the IT sector as a whole and its areas. In the current conditions, this measure is not enough to resolve the problems related to the development of domestic IT products and services. Based on the current situation analysis and the problems identified, the author proposed a new strategic approach to the IT sector development. It aims at designing a single complex strategy that covers all industries of the Russian IT sector. As a result, the state support system should move from its current stimulating paradigm to a program-targeted one.
DEVELOPMENT OF AN ALGORITHM FOR CLASSIFYING SOCIO-ECONOMIC SYSTEMS OF REGIONS BY THE LEVEL OF INNOVATION POTENTIAL MANAGEMENT
Authors:   Voronezh State University of Forestry and Technologies named after G.F. Morozov, A. Azarova Natalya
Published: February 2025

Background. In modern conditions the economic success of regional development is determined by the speed of managerial responses to changes and challenges in the external environment. The purpose of the study was to develop an algorithm for classifying socio-economic systems according to the level of management of innovation potential of the regions, as part of the long-term objectives of building a competitive economy, which is an important factor in achieving technological sovereignty of the country. Materials and methods. When compiling the dataset of actual values of the integral level of performance of the tools of management of innovation potential of socio-economic mesosystems the analytics of Leontief Centre – AV Group Consortium (LC-AV), based on the data of Rosstat version 2022 on the data of 2020–2021 was used. The article applied methods of univariate clustering based on the Fisher algorithm, hierarchical cluster analysis, k-means clustering, fuzzy clustering. Euclidean distance was used to assess dissimilarity, Ward's method of agglomeration was used, centring was not performed, truncation was determined based on the adapted Hartigan index. Results. An 8-stage process of selecting an effective data clustering algorithm is proposed for application. Identification of 85 socioeconomic mesosystems of the Russian Federation using the author's methodology of classification by the level of innovation potential management is carried out. Conclusions. In the matrix of balanced scientific and technological development the influence of innovation potential management factors on five groups of socio-economic mesosystems clusters (strong, medium-strong, medium, medium-weak and weak innovators) was investigated, which will give further opportunity to develop managerial decisions regarding the development of differentiated strategies and policies adapted to the needs and characteristics of each mesosystem in order to improve competitiveness, technological sovereignty and quality of life.
MATHEMATICAL MODELING OF A PULSATING HEART WITH VENTRICULAR SEPTAL DEFECT
Authors:   Tambov State Technical University, V. Frolov Sergey , E. Sudakov Dmitriy ,   Tambov State Technical University, A. Korobov Artem ,   Tambov State Technical University
Published: February 2025

Background. The paper considers the problem of creating a mathematical model of a heart with a congenital anomaly of the interventricular septum. This malformation is one of the most common and occurs both separately or in combination with other abnormalities. Materials and methods. The mathematical model refers to zero-dimensional models of blood circulation and consists of sequentially connected active and passive chambers. Laplace's law for a thin-walled sphere, a 4-element Hill muscle model and an augmented Starling's law are used to model active chambers. The ventricular septal defect in the model is represented by the equations of connection between the ventricles. Results. Examples of numerical studies of the model are given, on the basis of which a strong effect of an interventricular septal defect on general blood circulation has been established. Conclusions. The model will provide additional information for early diagnosis, as well as become the basis for medical decision support systems in cardiology practice.
A MODEL FOR ASSESSING THE LOSSES OF COMMERCIAL STRUCTURES IN THE IMPLEMENTATION OF FORECASTED RISKS
Authors:   Voronezh Institute of the Federal Penitentiary Service of Russia, V. Lubentsov Aleksandr
Published: February 2025

Background. The risks to which state and commercial facilities are exposed are currently particularly frequent. The purpose of the work is to propose a proven methodology for assessing the impact of risks and countering them. Materials and methods. The article provides a systematic analysis of non-informational risks to which commercial and government facilities are exposed. Risk ranking is proposed to be carried out according to the cascade MAI model. Results. The methodology for assessing the parameters of the probability of the risks, possible damage, and the necessary costs of counteraction is given. Methods of countering risks are proposed. Examples of calculations are given for two real commercial structures in a large regional center – a non-food storage warehouse and a nonfood store in a large shopping center. Estimates of the impact of risks and the cost of losses are given. Conclusions. Conclusions are drawn about the applicability of methods of countering the risks considered.
NONLINEAR PHENOMENA AND STABILITY OF FUNCTIONING OF THE INDUSTRIAL SYSTEM IN A DIGITALIZED ECONOMY
Authors:   Baikal State University, V. Chuprov Sergey , V. Babkin Aleksandr ,   Peter the Great St. Petersburg Polytechnic University
Published: February 2025

Background. With the increasing digitalization of the Russian economy, understanding the dominant trends in the distribution and protection of information flows in a non-stationary space is gaining theoretical and practical significance. An evolving industrial system immersed in such environments is characterized by highly disturbed processes and metamorphoses displayed by nonlinear phenomena, measures of chaos and order of its behavior. On this basis, taking into account the discussed phenomena, the article is aimed at analyzing and ensuring the stability of the industrial system in the face of the impact of both flows of technological and product innovations of the digitalized economy and geopolitical and economic threats that aggravate the behavior of the system. Materials and methods. The theoretical and methodological basis of the study was formed by the doctrines of thermodynamics, statistical physics, nonlinear dynamics, concepts and methods of theories catastrophe, communication and information, cybernetics and synergetics, evolutionary and innovative economics and production management. Results. Using their ideas and analytics, the concepts of entropy, chaos and the effect of the functioning of the system supported by the control information coming into it are revealed. Within the framework of information theory, the influence of signal and noise parameters on information processes in the economy, the features of their transmission and distortion are characterized. In the context of the statistical dependence of the effect of the economic system's activity on the control information accumulated in it, the transformation and interpretation of this exponential dependence with measures of the order of behavior of the industrial system are performed. Nonlinear phenomena of this dependence and the evolution of the industrial system are interpreted in order to achieve its stable effect. Conclusions. The study complements theoretical ideas about the factors ensuring the stability of the functioning of modernized industrial systems and argues for the need for a symbiosis of natural and economic sciences to deepen the analysis and interpretation of the phenomena of the evolution of chaotic industrial systems in a digitalized economy.
NEURAL NETWORK PROCESSING OF ASYNCHRONOUS MOTOR STATE PARAMETERS IN CASE OF INTER-TURN CLOSURE
Authors:   Belarusian State University of Transport, V. Mirosh Dmitry
Published: February 2025

Background. The technical diagnostic tools used today in the repair and maintenance of asynchronous motors are an important aspect of the functioning of the most important devices in enterprises. Asynchronous drive is used in many areas of human activity, in industry as well as in everyday life. Materials and methods. The materials of this article present the technology of using convolutional neural networks for the diagnosis of inter-turn circuits in three-phase asynchronous motors with a short-circuited rotor, based on the use of a graphical representation of the relations of energy characteristics. Results. Data on vibration studies of traction electric motors of diesel locomotives, as well as direct measurements of the current of the studied asynchronous electric motors, were used as material for testing the capabilities and testing of the neural network. Conclusions. The use of the developed neural networks allows to improve diagnostic studies for asynchronous machines of various capacities, easily adapt them to different dimensional designs, improve the quality of diagnostic services provided and reduce the labor costs of diagnostic specialists in the study of the parameters of the state of an electric machine.
Studies of bat fauna (Chiroptera: Vespertilionidae) in protected areas of the Republic of Tatarstan
Authors:   Volga-Kama Natural Biosphere Reserve, I. Egorov Maksim , G. Smirnov Dmitriy ,   Penza State University, V. Shulaev Nikolay ,   Kazan Federal University, R. Saitov Vadim ,   Kazan Federal University, A. Zaripov Amir ,   Children's house of creativity "Tankodrome", S. Gridneva Aleksandra ,   Kazan Federal University, R. Fattakhova Amina ,   Children's house of creativity "Tankodrome"
Published: February 2025

Background. Reliable information on the species composition and ecological char acteristics of bats, especially in protected areas, is necessary for adequate planning and im plementation of monitoring and conservation measures for both their populations and the natural communities they inhabit. However, due to poorly studied bats in the Republic of Tatarstan this is not possible. In order to solve this problem, we started their targeted studies. The purpose of the study was to summarize the data we obtained on the capture of bats in recent years in several protected areas. Materials and methods. Studies were con ducted from May to August 2022–2024 at two sites of the Volga-Kama Nature Reserve, Kichki-Tan Sanctuary and Selengushka Lake, Nurlat District. Bats were captured with spidernets. Results. Sixty-two individuals of 7 species of bats were captured during the work conducted at four locations: Myotis nattereri, M. brandtii, M. daubentonii, M. dasycneme, Nyctalus. noctula, Pipistrellus nathusii and P. pygmaeus. The finding of M. brandtii and P. pygmaeus were made in protected areas for the first time. Conclusions. M. daubentonii, M. dasycneme, N. noctula, P. nathusii and M. brandtii were found to be the most common species. M. nattereri, P. pygmaeus and N. lasiopterus should be considered as minor species. As a result, the total species composition of bats in the considered sites is currently represented by 10 species, which is 76,9 % of the entire bat fauna of Tatarstan.
Preliminary data on the genetic structure of the population of stray dogs in Penza
Authors:   Penza State University, V. Kuzmin Aleksandr
Published: February 2025

Background. A domestic dog (Canis familiaris) is one of the most common do mestic animals, the diversity of their ecological and social status is determined by their re production and reproduction in cities and rural settlements. In populated areas, dogs have a significant impact on the fauna of the ecosystem. The purpose of the study was to analyze the genetic structure of Penza stray dog population based on the study of individual polymor phism by microsatellite loci of nuclear DNA. Materials and methods. The material for the study was hair samples of domestic and stray dogs collected in the period 2021–2024 in shelters and centers for overexposure of stray animals, on the streets of Penza and provided by pet dog owners. To isolate DNA, 23 wool samples were collected, of which 11 were ob tained from stray dogs and 12 from domestic dogs. To amplify microsatellite DNA fragments consisting of tri- and tetra tandem repeats, the primer systems of the Stock Marks Dog Gen otyping Kit identification panel of the American Kennel Association were used. Results. The approbation of 6 microsatellite systems (PEZ3 F/R, PEZ6 F/R, PEZ8 F/R, FHC2010 F/R, FHC2045 F/R, FHC2079 F/R) showed that they are extremely nonspecific for the DNA matrix obtained from dogs living in the territory of the Russian Federation. Apparently, the genetic lines of the domestic dog of the North American continent are quite different from domestic lines. The obtained microsatellite allelic spectra of DNA samples from stray and domestic dogs are mainly represented by heterozygous sets. At the same time, heterozygosity was slightly higher in the population of stray dogs (0.750) compared with the heterozygosity of domestic dogs (0.670). Conclusions. The performed procedure for DNA extraction from hair samples of domestic and stray dogs revealed its low productivity. For a successful study of the genetic structure of the population of stray animals, more productive methods should be used, for example, tissue biopsy. The results of amplification of marker fragments of microsatellite DNA of stray dogs showed poor performance of the tested microsatellite systems of the dog identification panel of the American Kennel Association. It is necessary to start developing its own panel of microsatellite markers suitable for the identification of dogs of domestic cultural breeding.
The use of epin-extra plant growth regulator for green cuttings of pear varieties in a greenhouse with artificial fog
Authors:   I.V. Michurin Federal Scientific Center, V. Zatsepina Ilona
Published: February 2025

Background. Plant growth regulator epin-extra is a good substance for various crops. Thanks to this preparation, plants take root easily and simply, you can grow healthy planting material, fruits are well tied on fruit trees and do not crumble. The purpose of our research is to use the plant growth regulator epin-extra to root green cuttings of pear varieties in a greenhouse with a film shelter. Materials and methods. In the course of the work, experimental studies were conducted to study the rootability of green cuttings on pear varieties – Yakovlev's Memory (k), August dew, Seedless, Hera, Irista, Beauty Chernenko, Skorospelka from Michurinsk, Extravaganza, February souvenir, Miracle worker, Allegro, Yakovlev's Fa vorite, Tenderness, Pervomayskaya, Svetlyanka. The pear varieties February souvenir, Yakovlev's Memory (k), Skorospelka from Michurinsk, Extravaganza, Allegro had the greatest rootability when using the plant growth stimulator epin-extra (1.0 mg/l) for 24 hours. Without the use of a plant growth stimulant, pear varieties February souvenir, Yakovlev's Memory (k), Skorospelka from Michurinsk, Extravaganza, Allegro possessed. Results and conclusions. The greatest height of growth, the diameter of the conditional root neck, the number of roots, the length of the roots when treated with the plant growth stimulant epin-extra (1.0 mg /l) for 24 hours and without the use of a plant growth stimulant were demonstrated by the pear varieties February souvenir, Yakovlev's Memory (k), Skorospelka from Michurinsk, Extravaganza, Allegro.
INDICADORES DO BRASIL NO GII 2020 E DECISÕES DE INVESTIMENTOS EM POLÍTICAS PÚBLICAS
Authors: Moreira Aldemir Freire , Câmara Samuel Façanha , Tahim Elda Fontinele , Lopes Júnior Elias Pereira , Barbosa Eufrasina Campelo Borges Mendonça
Published: February 2025

São diversas as pesquisas que concluem que a inovação tem papel primordial no desenvolvimento econômico de um país. Além disso, a jornada de inovação é resultado de uma participação compartilhada de atores, entre os quais, o setor público, com suas políticas voltadas para a inovação. Para tanto, faz-se necessário utilizar parâmetros e instrumentos de mensuração para avaliá-las e gerenciá-las. O Brasil, especificamente, se situa entre os 5% maiores países do mundo, no entanto, ocupa posições incômodas nos índices de inovação e empreendedorismo, o que conduz à urgência de ações direcionadas a melhorar este posicionamento. Com este trabalho, busca-se avaliar os indicadores do Brasil mais mal posicionados no Global Innovation Index de 2020 e o seu impacto com relação às decisões de investimentos em políticas públicas. Tais indicadores são escalonados por ordem decrescente de impacto na inovação através de modelos matemáticos. Os escalonamentos realizados não são semelhantes entre as formas de cálculo e alguns se mostram inclusive indiferentes à promoção da inovação. Verifica-se assim discordâncias quanto aos indicadores apontados como fracos pelo GII 2020 como prioridade de investimento com vista a melhorar o posicionamento do Brasil no contexto da inovação. Portanto, os indicadores do Brasil mal posicionados no GII 2020 não necessariamente devem ser priorizados nas políticas públicas voltadas para a inovação e se propõe uma seleção de indicadores que melhor impactam a inovação.
In-silico Approach to Combat Methicillin-resistant Staphylococcus aureus: Targeting RelP Protein with Inhibitor Peptide to Mitigate Drug Resistance
Authors: Sinoliya Priyanka , Solanki Pooran Singh , Niraj Ravi Ranjan Kumar , Sharma Vinay
Published: February 2025

Background:

Methicillin-resistant Staphylococcus aureus (MRSA), known for its re-sistance to multiple antibiotics, has emerged as a major global health concern. It facilitates biofilm formation under stressful conditions by catalyzing the synthesis of alarmones (p)ppGpp and ppGpp. These alarmones on accumulation lead to biofilm formation and cause resistance towards antibiotics.

Methods:

This condition has prompted the exploration of various novel approaches and methodolo-gies to combat MRSA infections. Among these, peptide therapeutics stand out as a promising next-generation treatment option. In this study, ninety antimicrobial peptides were sourced from the anti-microbial peptide database and the other sixty-one peptide sequences were designed using the Pep-draw server. These peptide sequences were screened out using different in-silico tools. The protein-peptide molecular interaction was studied using a molecular docking and molecular dynamic simu-lation technique.

Result:

Out of 151 peptide sequences, Pantocin wh-1 emerged as the most promising drug candidate. Both molecular interaction studies and molecular dynamics simulations demonstrated positive re-sults.

Conclusion:

Peptide therapeutics is a novel approach researchers are presently exploring as it pro-vides prompt significant results and promotes a new insight towards dealing with conditions like MDR. Pantocin wh-1 is a peptide drug currently listed as an accessible anti-tuberculosis peptide, and this study suggests the repurposing of this drug as a viable treatment option for MRSA infections.
A vezetés és szervezés kapcsolata a minőségmenedzsmenttel: szisztematikus irodalom elemzés
Authors: Tóth Barna , Szűcs Edit
Published: February 2025

This publication is intended to examine the close relationship between quality management and leadership and organization, highlighting the possibilities of increasing organizational efficiency in both industrial and non-industrial environments. During the systematic literature review, we examined the role of leadership, the closely related organizational culture, and quality management. The publication aims to explain how quality systems and frameworks, such as ISO and the EFQM model, support strategic planning and sustainability, thus providing direction for modern organizations. The research emphasizes the importance of digital transformation and knowledge management, and we have formulated the future research goals that can advance the productivity of organizations.
When Should We Raise Clinical Suspicion of DiGeorge Syndrome: Two Case Reports from a Tertiary Hospital in Indonesia
Authors: Sari Joni Indah , Sihombing Nydia Rena Benita , Maharani Nani , Tri Indah Tri Indah , Utari Agustini
Published: February 2025

DiGeorge syndrome (DGS) or 22q11.2 deletion syndrome (22q11.2DS) is the most common genetic microdeletion in humans, with an incidence rate of 1:3000 to 6000 live births. Early detection and diagnosis of DiGeorge syndrome are challenging to clinicians due to its phenotype variability. We report two cases of DiGeorge syndrome, each demonstrating a different combination of clinical phenotypes. Two girls (2 years-3 months old and 2 years-2 months old) were diagnosed with 22q11.2DS following chromosomal microarray analysis (CMA) results. The patients in both cases showed some similar clinical phenotypes, including developmental delay, seizure, recurrent infections, hypothyroidism, and dysmorphic features (down-slanting palpebral fissure, bulbous nose, low-set ears, and small down-turned mouth). However, the patient in case 2 exhibits more typical phenotypes, including congenital heart defect and hypocalcemia. Besides congenital heart anomalies, clinicians should raise clinical suspicion of DiGeorge syndrome in the presence of developmental delay, seizure, signs of immunodeficiency (recurrent infections), and dysmorphic features in children. Phenotype variability of DiGeorge syndrome is primarily attributed to the specific gene involved in the deletion, incomplete penetrance, and variable expressivity.
Reducing heavy drinking through the ‘sober curious’ movement (Preprint)
Authors: Ward Paul Russell , Savic Michael , MacLean Sarah , Lunnay Belinda , Lyons Antonia , Huighes Tonda , London Kerry , Caluzzi Gabriel , Pettigrew Simone , Pennay Amy , Meyer Samantha , Duncan Tristan , Lee Nicole
Published: February 2025

UNSTRUCTURED

Alcohol consumption is socially accepted in Australia and places where alcohol is not served are rare. However, alcohol remains a major public health concern. Since COVID-19, alcohol consumption has increased even more, increasing non-communicable disease risks, social harms and economic costs. The socially engrained nature of alcohol consumption adds complexity to designing successful reduction approaches. Rather than implementing another intervention, we will undertake a natural experiment on the 'sober curious' movement, which got momentum through social media influencers promoting the idea of reducing alcohol consumption for wellness. The increased demand for alcohol-free substitutes has driven a massive increase in the availability of alcohol-free wines, beers and spirits in retailers, bars and restaurants.

The project will be undertaken in 3 stages. Stage 1 will examine the supply-side of alcohol-free products. A social media analysis of marketing by alcohol-free producers/distributors will generate an understanding of their techniques and which population groups they target. In-depth interviews with producers will create evidence on the intentions behind making alcohol-free products available, their target market and if/how they balance providing non alcoholic products alongside alcohol. Stage 2 will be a qualitative study with three case-study groups who have high alcohol consumption - male construction workers, LGBTQ+ people and young adults in rural/regional areas. This stage will provide a deep understanding of the reasons for their alcohol consumption, the potential for alcohol-free products in their lives, and possible interventions for reducing their consumption in a sustainable way. Stage 3 will involve Deliberative Symposia with non-alcoholic beverage producers/distributors, representatives from our case study groups, public health professionals and policy makers to develop co-designed interventions for alcohol reduction in the case-study groups.
“I Finally Love Who I See in the Mirror”: American Substance Users’ Reconstruction of Individualized Identity in the Recovery Trajectory
Authors: Yaqubi, PhD Mojde
Published: February 2025

Substance use disorder (SUD) imposes a significant economic burden on the United States, with costs related to healthcare, criminal justice, and lost productivity. Despite its prevalence, recovery remains underexplored, particularly regarding identity reconstruction and its economic implications. To the best of my knowledge, no study focuses on Americans’ identity reconstruction (social or individualized) in recovery, particularly in online platforms. This study specifically examines how ‘individualized identity’ is constructed in substance use recovery, an area with limited research. It explores the stages and themes of individualization in American substance users’ identity statements published on public recovery platforms. A macro-level analysis identifies three stages of individualized Identity reconstruction (Webb et al., 2022)—staying safe, exploring, and self-determining—each associated with psychological, social, and economic challenges. Individuals in recovery navigate financial instability, employment barriers, and housing insecurity, all which impact reintegration. A key finding is the role of stigma management in later recovery stages, where individuals reframe societal perceptions to improve their social and economic prospects. Additionally, the ‘individualized voice’ was examined from a linguistic perspective (Helms-Park & Stapleton, 2003), revealing a shift from dependency on external validation to assertive self-identification. The findings suggest that effective recovery policies should incorporate economic support mechanisms and reduce structural barriers to long-term reintegration.
“Memoir Novel” by E. Grishkovetz in Terms of Poetics of “Autofiction”
Authors:   North-Caucasus Federal University, Bronskaya Lyudmila I. , Ivanova Irina N. ,   North-Caucasus Federal University
Published: February 2025

The purpose of the article is to define poetics and genre peculiarities of the memoir novel “Theater of Despair. Desperate Theater” by E. V. Grishkovetz. Results. The synthetic and even oxymoronic nature of the genre (memoirs assume the reality of what is described, “it did happen”, while novel is a work of fiction) poses specific aesthetic tasks and problematizes the author – hero – reader relationship again. Grishkovetz’s memoir novel is an example of “autofiction” genre, which is popular in the contemporary Western European and Russian literature. Its characteristic features are, first of all, the special status of the writing subject, a specific type of discourse, the verbalization of personal experience, mostly traumatic one, and the synthesis of what really happened with artistic fiction — with emphasis on extreme sincerity. Grishkovetz’s version is also complicated by author’s reflection as a writer, because this is a text about personal becoming of a writer, a stage director and an actor who created a unique kind of author’s theatre which paradoxically excludes everything “too personal” except for the events that provided background and material for Grishkovetz’s fictional prose and theatrical performances. The novel is regarded in the context of contemporary Russian literature and the recent discussions on genres of autobiography and autofiction.
The Right-bank Tsimlyanskaya Fortress in the Historiography of the first third of the 20th Century
Authors:   Institute of Archeology RAS, Flyorov Valeriy S.
Published: February 2025

Introduction. The monument of the Right-bank Tsimlyanskaya fortress has been included in the archaeological literature since the 19th century under the traditional definition of “hillfort,” however, it is advisable to call it a “fortress”, as well as the Sarkel located on the opposite bank of the Don. The purpose of this work is to review the scientific biographies of archaeologists who studied the Right-bank Tsimlyanskaya fortress, highlighting their role and contribution to the study of the monument. Results. The paper summarizes the scientific biographies of archaeologists A. A. Miller and M. A. Millerov, M. I. Artamonov, I. I. Lyapushkin, historian Yu. V. Gauthier, popularizer B. V. Lunin. From 1926 to 1940, researchers played a major role in the study of the Right-bank Tsimlyanskaya fortress and the Khazar archeology of the Lower Don in general. A. A. Miller conducted a systematic survey of the Lower Don monuments of the Khazar Khaganate, described their condition at that time. A. A. Miller’s recognition of the settlement as a fortress retained its value until the beginning of the
21st century. M. A. Miller identified ceramics from fragments, which is now called Saltovo-Mayatskaya. B. V. Lunin considered the problems of periodization and cultural attribution of ancient settlements. In the study of the Khazars, Yu.V. Gauthier was the last predecessor of M. I. Artamonov. M. I. Artamonov was the first author to describe the actual material culture of the Khazar Khaganate on the Lower Don. M. I. Artamonov agreed with A. A. Miller that the monument is the remains of a fortress and for the first time introduces the concept of “Saltovo-Mayak type settlements”. Later excavations confirmed M. I. Artamonov’s assumption about the construction of the Right-bank fortress earlier than the Sarkel fortress. The excavations of 1987–1990, 2006–2021 confirmed the fact of the construction of the Right-bank fortress in a place not previously occupied by the settlement. The student of M. I. Artamonov, I. I. Lyapushkin, continued his study of the Right-bank fortress. The works of the scientists retain their significance to the present day.
The Fight against Alcoholism in Astrakhan Oblast at the Turn of the 1970s-1980s According to Written Sources from the State Archive of Astrakhan Oblast
Authors:   Kalmyk Scientific Center of the RAS, Baduginova Margarita V.
Published: February 2025

The study of the history of health care in the Astrakhan region in the post-war period is impossible without archival documents; especially interesting are official sources in the form of certificates, reports, statistical data, and protocols. The purpose of the study is to introduce new sources covering the fight against alcoholism in one of the regions of the RSFSR, as well as the materials of the Commission on the fight against drunkenness and alcoholism, formed under the Executive Committee of the Regional Council of People’s Deputies of the Astrakhan Oblast. Results. The article covers for the first time the work of the Commission to Combat Alcoholism under the Executive Committee of the Regional Council of People’s Deputies of the Astrakhan region, the preventive measures taken to prevent alcoholism, and statistical data on this issue. A reference, which had the ‘Secret’ classification, is published, which contains a report on the implementation by the city of Astrakhan of the normative-legal documents issued to strengthen the fight against drunkenness and alcoholism in the country, as well as measures implemented in the framework of intensification of the fight against drunkenness. Conclusions. The data obtained during the study of archival documents will help to study that historical period more deeply, to understand the political and economic processes that took place, the state of the sphere of human health protection in the Astrakhan region.