bluuebunny/crossref_metadata_2025 huggingface dataset:
Het belang van conservatoir beslag ter verzekering van niet opeisbare erfrechtelijke vorderingen
Authors: Perrick S.
Published: October 2016

Het belang van conservatoir beslag ter verzekering van niet-opeisbare erfrechtelijke vorderingen

Dit artikel behandelt de relevantie van een recent arrest van de Hoge Raad voor de mogelijkheid om conservatoir beslag te leggen voor niet opeisbare erfrechtelijke vorderingen van kinderen op de langstlevende. Dit conservatoir beslag kan in het bijzonder van belang zijn in de gevallen dat de niet opeisbaarheid niet wordt gerechtvaardigd door de ruim opgevatte verzorgingsbehoefte van de langstlevende.

De voorzieningenrechter dient het belang van het kind om de voldoening van zijn vordering zeker te stellen en het belang van de langstlevende om over het beslagen goed te kunnen beschikken, af te wegen. Hij dient praktisch om te gaan met het voorschrift dat na het beslag de eis in de hoofdzaak wordt ingesteld.
Wat brengt de Wet bescherming erfgenamen tegen schulden?
Authors: van der Geld L.A.G.M.
Published: October 2016

Wat brengt de Wet bescherming erfgenamen tegen schulden?

Op 1 september 2016 is de Wet bescherming erfgenamen tegen schulden (Wet BETS) in werking getreden. Deze wet brengt onder meer met zich een wijziging van de aanvaardingsfictie van artikel 4:192 BW en de mogelijkheid aan de kantonrechter bescherming te vragen tegen onverwachte schulden. In deze bijdrage worden de gevolgen van de inwerkingtreding van deze wet besproken.
The essence of road safety in Poland. Recognition of theoretical and empirical
Authors: Przybytniowski Jarosław W. , Pacholarz Wioletta M.
Published: October 2016

This article consists of two parts. The first part is based on the theoretical analysis of the concept of safety and prevention measures in road traffic, described in the existing literature and statistics. Whereas the second part focuses on the analysis of vehicle insurance as a financial instrument of economic safety of road traffic participants. In the 21st century, one of very important problems, not only socially but also economically, referring to Poland and other EU countries is the ongoing development of motorisation and, consequently, the progress in transportation. Unfortunately, this development sometimes leads to the growing number of road accidents and their effects.
European Union environmental security: the only achieving strategy
Authors: Melnyk Olena , Koreneva Inna , Zahorodnya Lyudmyla , Danyl'chenko Iryna
Published: October 2016

The article deals with the main environmental policy stages in the EU. The principles of environmental protection are given. The legal environmental protection framework is considered. The features of regions with natural and common resources, industrial and human potential that has its own action plan for achieving common EU environmental safety strategy are considered.
Estimation of Loads Acting on Flaps of the Su-22 Aircraft for Fatigue Tests
Authors: KOWALECZKO Grzegorz , LESKI Andrzej , ZIELIŃSKI Wojciech
Published: October 2016

The paper presents the results of the calculation of forces acting on the flaps of the Su-22 aircraft during take-off and landing. Four different analytic and experimental calculation methods were used to increase the reliability of the obtained results. The results will be the basis for performance of fatigue testing of the flaps which are structural components of the aircraft wings. The tests will be performed as part of
a wider research program aimed at the extension of the Su-22 aircraft service life.
Perfil diferencial de trastornos de personalidad en el consumo de drogas y maltrato
Authors: Castillo Fernández Eva , Gómez Sánchez Enrique J. , Mata-Martín José Luis , Ramírez Ucles Isabel , López Torrecillas Francisca
Published: October 2016

ResumenExiste evidencia empírica que demuestra la relación entre patrones de personalidad, tipos de delitos violentos y consumo de drogas o alcohol. El presente estudio tiene como objetivo examinar la tasa de prevalencia de trastornos de personalidad en prisión (consumidores de drogas y maltratadores), utilizando como grupo control población encarcelada sin este tipo de delitos. Participaron en este estudio 45 hombres del Centro Penitenciario de Albolote (Granada) (15 consumidores de drogas, 15 maltratadores y 15 controles) que fueron seleccionados mediante la Escala de Severidad de la Adicción (EUROPASI; Bobes et al., 1996) y la Escala de Tácticas de Conflicto (CTS2; Strauss et al., 1996). Para evaluar los trastornos de personalidad se utilizó el Inventario Clínico Multiaxial de Millon. Encontramos que el grupo de consumo de drogas puntúa más alto en los trastornos de personalidad histriónico, antisocial, límite y agresivo-sádico en comparación con el grupo de maltrato y control y que el grupo de maltrato puntúa más alto en el trastorno de personalidad dependiente en comparación con el grupo de drogas y control. Nuestros resultados resaltan la necesidad de tener en cuenta la existencia de trastornos de personalidad en población clínica con el fin de diseñar estrategias de intervención y prevención para el consumo de drogas y el maltrato. AbstractThere is empirical evidence showing the relationship between personality disorders, violence crime and substance abuse problem. This study aims to examine the prevalence of personality disorders in prison populations (drug abusers and abusers), using as a control group a population imprisoned without these types of crimes. The participants were 45 men within the prison in Albolote (Granada) (15 drug abusers, 15 abusers and 15 control) and were selected following the Severity Addiction Scale (EUROPASI; Bobes et al., 1996) and the Conflict Tactics Scale (CTS2; Strauss et al., 1996). The Millon Clinical Multiaxial Inventory was used to assess personality disorders. We found that drug abusers had higher scores than abusers and controls in histrionic, antisocial, borderline and aggressive-sadistic, and abusers had higher scores than drug abusers and controls in dependent personality disorder. Our results highlight the need to take into account the existence of personality disorders in clinical population in order to design prevention and intervention strategies for drug abuse and domestic violence.
The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices
Authors: Sevelius Jae M , Deutsch Madeline B , Grant Robert
Published: October 2016

Introduction

Globally, transgender (“trans”) women are one of the key populations most disproportionately impacted by HIV. Pre‐exposure prophylaxis (PrEP) is the newest and most promising biomedical HIV prevention intervention to date. This paper reviews relevant literature to describe the current state of the science and describes the potential role of PrEP among trans women, including a discussion of unique considerations for maximizing the impact of PrEP for this vulnerable population.

Methods

Available information, including but not limited to existing scientific literature, about trans women and PrEP was reviewed and critiqued based on author expertise, including PrEP clinical trials and rollout.

Results

To date, PrEP demonstration projects and clinical trials have largely excluded trans women, or have not included them in a meaningful way. Data collection strategies that fail to identify trans women in clinical trials and research further limit the ability to draw conclusions about trans women's unique needs and devise strategies to meet them. Gender‐affirming providers and clinic environments are essential components of any sexual health programme that aims to serve trans women, as they will largely avoid settings that may result in stigmatizing encounters and threats to their identities. While there is currently no evidence to suggest drug‐drug interactions between PrEP and commonly used feminizing hormone regimens, community concerns about potential interactions may limit interest in and uptake of PrEP among trans women.

Conclusions

In scaling up PrEP for trans women, it is essential to engage trans communities, utilize trans‐inclusive research and marketing strategies and identify and/or train healthcare providers to provide gender‐affirming healthcare to trans women, including transition‐related care such as hormone provision. PrEP implementation guidelines must consider and address trans women's unique barriers and facilitators to uptake and adherence.
Preventing HIV among adolescents with oral PrEP: observations and challenges in the United States and South Africa
Authors: Hosek Sybil , Celum Connie , Wilson Craig M , Kapogiannis Bill , Delany‐Moretlwe Sinead , Bekker Linda‐Gail
Published: October 2016

Introduction

Adolescents and young adults aged <25 are a key population in the HIV epidemic, with very high HIV incidence rates in many geographic settings and a large number who have limited access to prevention services. Thus, any biomedical HIV prevention approach should prepare licensure and implementation strategies for young populations. Oral pre‐exposure prophylaxis (PrEP) is the first antiretroviral‐based prevention intervention with proven efficacy across many settings and populations, and regulatory and policy approvals at global and national levels are occurring rapidly. We discuss available data from studies in the United States and South Africa on the use of oral PrEP for HIV prevention in adolescent minors, along with some of the implementation challenges.

Discussion

Ongoing studies in the United States and South Africa among youth under the age of 18 should provide the safety data needed by the end of 2016 to contribute to licensure of Truvada as daily PrEP in adolescents. The challenges of completing these studies as well as foreseeable broader challenges highlighted by this work are presented. Adherence to daily PrEP is a greater challenge for younger populations, and poor adherence was associated with decreased efficacy in all PrEP trials. Individual‐level barriers include limited familiarity with antiretroviral‐based prevention, stigma, product storage, and social support. Structural challenges include healthcare financing for PrEP, clinician acceptability and comfort with PrEP delivery, and the limited youth‐friendly health services available. These challenges are discussed in the context of the work done to date in the United States and South Africa, but will likely be magnified in the setting of limited resources in many other countries that are heavily impacted by HIV.

Conclusions

Adolescent populations are particularly vulnerable to HIV, and oral PrEP in these populations is likely to have an impact on population‐level HIV incidence. The challenges of disseminating an HIV biomedical prevention tool requiring daily usage in adolescents are formidable, but addressing these issues and starting dialogues will lay the groundwork for the many other HIV prevention tools now being developed and tested.
Commentary: the value of PrEP for people who inject drugs
Authors: Coleman Rosalind L , McLean Susie
Published: October 2016

Introduction

The offer of pre‐exposure prophylaxis (PrEP) is recommended as an additional option for HIV prevention for people at substantial risk of HIV infection as part of combination HIV prevention approaches. Implementing this depends on integrating PrEP in public health programmes that address risky practices with evidence‐based interventions, and that operate in an enabling legal and policy environment for the delivery of health services to those at higher risk of HIV infection. What does this recommendation mean in terms of the diverse range of HIV prevention needs of key populations, some of whom are so discriminated against that they exist essentially outside formal systems such as national public health services, and for whom a substantial risk of HIV is part of a larger adverse and hostile situation? We discuss this question with reference to people who inject drugs, informed by concerns and comments that emerged from a series of consultations.

Discussion

HIV prevention is part of a spectrum of injecting drug users’ priorities, and their access and uptake of HIV prevention services is contingent on their wider “risk environment.” The need to address structural barriers to services and human rights violations, and to improve access to comprehensive harm reduction programmes are of prime importance and would have higher value than a mono‐focus on HIV prevention. Where existing harm reduction activities are inadequate, fragile or dependent on external donors, shifts in funding priorities, including, for example, towards PrEP, could threaten investment in the broader programmes. For these reasons, it cannot be assumed that PrEP promotion will always be supported by people who inject drugs.

The sexual partners of people who inject drugs, non‐opioid users who also inject and for whom there is no established substitution treatment, as well as drug users who are unable to negotiate safe sex may value PrEP. As for all key populations, the involvement of people who inject drugs in shaping services for their consumption is vital and too often ignored.

Conclusions

For people who inject drugs and who experience discrimination, violence or harassment, implementation of PrEP should be guided by understanding and engaging with their interconnected range of needs, risk practices, priorities and options. The differentiated needs of sub‐populations that inject a range of drugs, and their sexual partners, require further exploration.
HID-1 is required for homotypic fusion of immature secretory granules during maturation
Authors: Du Wen , Zhou Maoge , Zhao Wei , Cheng Dongwan , Wang Lifen , Lu Jingze , Song Eli , Feng Wei , Xue Yanhong , Xu Pingyong , Xu Tao
Published: October 2016

Secretory granules, also known as dense core vesicles, are generated at the trans-Golgi network and undergo several maturation steps, including homotypic fusion of immature secretory granules (ISGs) and processing of prehormones to yield active peptides. The molecular mechanisms governing secretory granule maturation are largely unknown. Here, we investigate a highly conserved protein named HID-1 in a mouse model. A conditional knockout of HID-1 in pancreatic β cells leads to glucose intolerance and a remarkable increase in the serum proinsulin/insulin ratio caused by defective proinsulin processing. Large volume three-dimensional electron microscopy and immunofluorescence imaging reveal that ISGs are much more abundant in the absence of HID-1. We further demonstrate that HID-1 deficiency prevented secretory granule maturation by blocking homotypic fusion of immature secretory granules. Our data identify a novel player during the early maturation of immature secretory granules.
Simultaneous measurements of anisotropic thermal diffusivity and thermal effusivity of liquid crystals using temperature wave analysis method
Authors: Ryu Meguya , Morikawa Junko
Published: October 2016

Simultaneous measurements of anisotropic thermal diffusivity and thermal effusivity in the phase transition of the liquid crystal 4′-(pentyloxy)-4-biphenyl carbonitrile (5OCB), Cry–53–N–68–Iso, are demonstrated using the temperature wave analysis method. A detailed calibration procedure for determining thermal diffusivity (α), thermal effusivity (e), thermal conductivity (λ), and heat capacity per unit volume (Cp
ρ) is proposed utilizing hexaethylene glycol monododecyl ether (C12E6) as a calibration material, the heat capacity of which is precisely determined using a calorimetric method.
Photovoltaic properties of Cu2ZnSnS4 cells fabricated using ZnSnO and ZnSnO/CdS buffer layers
Authors: Tajima Shin , Umehara Mitsutaro , Mise Takahiro
Published: October 2016

To improve the photovoltaic properties of Cu2ZnSnS4 (CZTS) photovoltaic cells, we investigated the use of novel buffer layer materials. We found that Zn1−

x
Sn
x
O
y
fabricated by atomic layer deposition functioned as an effective buffer layer. The short-circuit current density increased by 10% because of a decrease in the absorption loss in the short-wavelength region. With Zn0.70Sn0.30O
y
layers, the conversion efficiency was 5.7%. To reduce interface recombination, a thin CdS layer was inserted between the ZnSnO and CZTS layers. The CZTS cells fabricated using ZnSnO/CdS double buffer layers showed a high open-circuit voltage of 0.81 V.
The single-species metagenome: subtypingStaphylococcus aureuscore genome sequences from shotgun metagenomic data
Authors: Joseph Sandeep J. , Li Ben , Petit III Robert A. , Qin Zhaohui S. , Darrow Lyndsey , Read Timothy D.
Published: October 2016

In this study we developed a genome-based method for detectingStaphylococcus aureussubtypes from metagenome shotgun sequence data. We used a binomial mixture model and the coverage counts at >100,000 knownS. aureusSNP (single nucleotide polymorphism) sites derived from prior comparative genomic analysis to estimate the proportion of 40 subtypes in metagenome samples. We were able to obtain >87% sensitivity and >94% specificity at 0.025X coverage forS. aureus. We found that 321 and 149 metagenome samples from the Human Microbiome Project and metaSUB analysis of the New York City subway, respectively, containedS. aureusat genome coverage >0.025. In both projects, CC8 and CC30 were the most commonS. aureusclonal complexes encountered. We found evidence that the subtype composition at different body sites of the same individual were more similar than random sampling and more limited evidence that certain body sites were enriched for particular subtypes. One surprising finding was the apparent high frequency of CC398, a lineage often associated with livestock, in samples from the tongue dorsum. Epidemiologic analysis of the HMP subject population suggested that high BMI (body mass index) and health insurance are possibly associated withS. aureuscarriage but there was limited power to identify factors linked to carriage of even the most common subtype. In the NYC subway data, we found a small signal of geographic distance affecting subtype clustering but other unknown factors influence taxonomic distribution of the species around the city.
A reappraisal ofTheroteinus(Haramiyida, Mammaliaformes) from the Upper Triassic of Saint-Nicolas-de-Port (France)
Authors: Debuysschere Maxime
Published: October 2016

The earliest mammaliaforms are difficult to assess because the fossil record is poor and because their distinctive morphologies cannot be directly compared with more recent mammaliaforms. This is especially true for the haramiyid genusTheroteinus, only known in the Saint-Nicolas-de-Port locality (Rhaetian, France). This study presents a new definition of the type-speciesTheroteinus nikolai. A new speciesTheroteinus rosieriensis, sp. nov., is named and distinguished by the lingual shift of distal cusps, a larger size, and a stockier occlusal outline. Comparisons withEleutherodon,MegaconusandMillsodonsuggest thatTheroteinushas potential close relatives among the Jurassic haramiyids.
Conjugate hemisphere ionospheric response to the St. Patrick's Day storms of 2013 and 2015 in the 100°E longitude sector
Authors: Kalita Bitap Raj , Hazarika Rumajyoti , Kakoti Geetashree , Bhuyan P. K. , Chakrabarty D. , Seemala G. K. , Wang K. , Sharma S. , Yokoyama T. , Supnithi P. , Komolmis T. , Yatini C. Y. , Le Huy M. , Roy P.
Published: October 2016

The effects of the St. Patrick's Day geomagnetic storms of 2013 and 2015 in the equatorial and low‐latitude regions of both hemispheres in the 100°E longitude sector is investigated and compared with the response in the Indian sector at 77°E. The data from a chain of ionosondes and GPS/Global Navigation Satellite Systems receivers at magnetic conjugate locations in the 100°E sector have been used. The perturbation in the equatorial zonal electric field due to the prompt penetration of the magnetospheric convective under shielded electric field and the over shielding electric field gives rise to rapid fluctuations in the F2 layer parameters. The direction of IMF Bz and disturbance electric field perturbations in the sunset/sunrise period is found to play a crucial role in deciding the extent of prereversal enhancement which in turn affect the irregularity formation (equatorial spread F) in the equatorial region. The northward (southward) IMF Bz in the sunset period inhibited (supported) the irregularity formation in 2015 (2013) in the 100°E sector. Large height increase (hmF2) during sunrise produced short‐duration irregularities during both the storms. The westward disturbance electric field on 18 March inhibited the equatorial ionization anomaly causing negative (positive) storm effect in low latitude (equatorial) region. The negative effect was amplified in low midlatitude by disturbed thermospheric composition which produced severe density/total electron content depletion. The longitudinal and hemispheric asymmetry of storm response is observed and attributed to electrodynamic and thermospheric differences.
Spatiotemporal reconstruction of Late Mesozoic silicic large igneous province and related epithermal mineralization in South China: Insights from the Zhilingtou volcanic‐intrusive complex
Authors: Wang Guo‐Guang , Ni Pei , Zhao Chao , Wang Xiao‐Lei , Li Pengfei , Chen Hui , Zhu An‐Dong , Li Li
Published: October 2016

Silicic large igneous provinces (SLIPs) generally reflect large‐scale melting of lower crustal materials and represent significant metal reservoirs. The South China Block‐Coastal Region (SCB‐CR) SLIP hosts several large epithermal deposits. To better understand these deposits, we document the spatiotemporal framework of the host SLIP across the SCB‐CR. Using zircon U‐Pb dating and geochemical and isotopic analysis, we identify four stages of emplacement. Stage 1 felsophyre (circa 149 Ma) shows a chemical affinity to highly fractionated I‐type granites. Stages 2 and 3 of low‐Mg felsic volcanics (circa 128 to 111 Ma) and stage 4 felsite (circa 100 Ma) have higherεHf(t) andεNd(t) values than stage 1 felsophyre, suggesting a significant contribution of newly underplated juvenile crust to the magma sources. Stage 4 diabase (circa 101 Ma) was likely produced by melting of subduction˗metasomatized asthenospheric mantle. Together with reliable published data, we build a new spatiotemporal framework of volcanics and infer that the majority of the SCB‐CR SLIP was related to the gradual northwestward subduction of the Izanagi plate beneath South China in a continental arc setting during circa 170 to 110 Ma, and minor contribution was from the eastward retreat of the subducting slab in a back‐arc setting during circa 110 to 90 Ma. We conclude that the large‐scale epithermal mineralization was generated by melting of the metal‐rich, thin (30–40 km), newly underplated hydrous juvenile crust during the tectonic transition from arc to back‐arc settings.
ATMS‐ and AMSU‐A‐derived hurricane warm core structures using a modified retrieval algorithm
Authors: Tian Xiaoxu , Zou Xiaolei
Published: October 2016

The Advanced Technology Microwave Sounder (ATMS) is a cross‐track microwave radiometer. Its temperature sounding channels 5–15 can provide measurements of thermal radiation emitted from different layers of the atmosphere. In this study, a traditional Advanced Microwave Sounding Unit‐A (AMSU‐A) temperature retrieval algorithm is modified to remove the scan biases in the temperature retrieval and to include only those ATMS sounding channels that are correlated with the atmospheric temperatures on the pressure level of the retrieval. The warm core structures derived for Hurricane Sandy when it moved from tropics to middle latitudes are examined. It is shown that scan biases that are present in the traditional retrieval are adequately removed using the modified algorithm. In addition, temperature retrievals in the upper troposphere (~250 hPa) obtained by using the modified algorithm have more homogeneous warm core structures and those from the traditional retrieval are affected by small‐scale features from the low troposphere such as precipitation. Based on ATMS observations, Hurricane Sandy's warm core was confined to the upper troposphere during its intensifying stage and when it was located in the tropics but extended to the entire troposphere when it moved into subtropics and middle latitudes and stopped its further intensification. The modified algorithm was also applied to AMSU‐A observation data to retrieve the warm core structures of Hurricane Michael. The retrieved warm core features are more realistic when compared with those from the operational Microwave Integrated Retrieval System (MIRS).
Dual Wavelength Laser Beam Cutting of High‐Performance Composite Materials
Authors: Fürst Andreas , Mahrle Achim , Hipp Dominik , Klotzbach Annett , Hauptmann Jan , Wetzig Andreas , Beyer Eckhard
Published: October 2016

The development of appropriate processes aims to shorten the cycle time of the production of parts, based on fiber reinforced polymers. Here, the laser can be a tool for the future, because the wear‐ and tool free processing expands the area of treatment processes. But laser processing is a challenging process due to the strong differing thermo‐optical properties of fiber‐ and matrix material. The present paper shows a solution to take these limitations into account. An experimental setup is applied to combine radiation with 1 and 10 μm. Thereby, the parameter and application window is expanded by the mixing ratio of radiation with both wavelengths. The present paper will show optimized parameters for different kind of materials as a result of this novel type of processing.
The Root Causes of the Limited Stability of Solution‐Coated Small‐Molecule Organic Light‐Emitting Devices: Faster Host Aggregation by Exciton–Polaron Interactions
Authors: Cho Yong Joo , Zhang Yingjie , Yu Hyeonghwa , Aziz Hany
Published: October 2016

The degradation mechanism is compared in organic light‐emitting devices (OLEDs) fabricated by solution‐coating to that in vacuum‐deposited OLEDs. Devices comprising various host materials made by vacuum‐deposition or solution‐coating are investigated. Changes in devices electroluminescence (EL) spectra during prolonged electrical driving are compared and analyzed. Hole‐only devices are also utilized, and employed to study the effects of charges and excitons, separately and combined. The results reveal that the faster degradation of solution‐processed devices relative to their vacuum‐deposited counterparts under electrical stress is due to a faster aggregation of the host materials. Interactions between excitons and polarons in the emitting layers of the devices induce this aggregation phenomenon. Although this phenomenon affects both vacuum‐deposited and solution‐coated emitting layers, it is found to occur much faster in the later. The findings shed light on the root causes of the limited stability of solution‐processed OLEDs.
Composites of Polymer and Carbon Nanostructures for Self‐Healing Chemical Sensors
Authors: Huynh Tan‐Phat , Khatib Muhammad , Srour Rawan , Plotkin Marian , Wu Weiwei , Vishinkin Rotem , Hayek Naseem , Jin Han , Gazit Oz M. , Haick Hossam
Published: October 2016

Despite recent dramatic development of materials with self‐healing ability, fabrication of a self‐healing devices remains challenging. In this paper, truly self‐healing composites consisting polymers and carbon nanostructures are reported. Using a modified fabrication technique – called “layer‐by‐layer stamping” – chemical sensors are produced and characterized by infrared spectroscopy and various microscopy techniques. As a demonstration of the ability of the developed sensors to coexist with harsh operation conditions, the performance of the sensors under exposure to volatile organic compounds that are derived from human breath/skin is evaluated under different conditions of cutting and self‐healing cycles. The results show a discrimination ability of the selected sensors to return to an operation level of 70%–100% after cutting and 24 h healing of the composite film. From this analysis, the discriminative power of the self‐healing sensor array remains high for the majority of analyte discrimination even after mechanical injury, thus strengthening the potential of such arrays for use in health monitoring applications based on detection of analyte patterns.
Transparent, Flexible, and Passive Thermal Touch Panel
Authors: Ruoho Mikko , Juntunen Taneli , Alasaarela Tapani , Pudas Marko , Tittonen Ilkka
Published: October 2016

This work presents a touch panel concept, which is enabled by a novel design of thin film thermocouples. The design offers a simple implementation by utilizing a single thin film to function as an array of thermocouples. The concept is demonstrated as a flexible, passive, and highly transparent touch panel. The passive nature of the thermoelectric touch recognition allows the performance of the presented sensor to be optimal at moderate sheet resistance values of the transparent conductive layers. Hence, the concept is highly potential for low‐cost large‐area applications and does not rely on costly low sheet resistance materials such as indium tin oxide. The demonstrator presented in this work achieves a signal‐to‐noise ratio of 20 with a rise time of 90 ms and is able to distinguish individual touches, sweeping with finger, as well as touching by multiple fingers at the same time. In addition, the concept may also be used in other thermal distribution mapping applications.
Subclinical dysphagia in persons with Prader–Willi syndrome
Authors: Gross Roxann Diez , Gisser Ronit , Cherpes Gregory , Hartman Katie , Maheshwary Rishi
Published: October 2016

Prader–Willi Syndrome (PWS) is caused by a genetic imprinting abnormality resulting from the lack of expression of the paternal genes at 15q11–q13. Intellectual disability, low muscle tone, and life‐threatening hyperphagia are hallmarks of the phenotype. The need for the Heimlich maneuver, death from choking, and pulmonary infection occur in a disproportionally high number of persons with PWS. The widely held belief is that eating behaviors are responsible for choking and aspiration; yet, no investigation had sought to determine if swallowing impairments were present in persons with PWS. To address this research and clinical gap, simultaneous videofluoroscopy and nasal respiratory signals were used to record swallowing function and breathing/swallowing coordination in 30 participants with PWS. Subjects consumed thin liquid and barium cookies under two randomized conditions as follows: (i) controlled (cues to swallow and standardized bolus sizes); (ii) spontaneous (no cues or bolus size control). Under videofluoroscopy, the cohort showed disordered pharyngeal and esophageal swallowing in both conditions with disturbances in timing, clearance, and coordination of swallowing with the respiratory cycle. No participant showed a sensory response such as attempting to clear residue or coughing; thereby supporting the lack of overt symptoms. We conclude that the high death rate from choking and pulmonary infection in children and adults with PWS may be related, in part, to underlying, asymptomatic dysphagia. The combination of rapid eating and dysphagia would increase the risk of aspiration‐related morbidity and mortality. © 2016 Wiley Periodicals, Inc.
Effects of pair bonding on dopamine D1 receptors in monogamous male titi monkeys (Callicebus cupreus)
Authors: Hostetler Caroline M. , Hinde Katherine , Maninger Nicole , Mendoza Sally P. , Mason William A. , Rowland Douglas J. , Wang Guobao B. , Kukis David , Cherry Simon R. , Bales Karen L.
Published: October 2016

Pair bonding leads to increases in dopamine D1 receptor (D1R) binding in the nucleus accumbens of monogamous prairie voles. In the current study, we hypothesized that there is similar up‐regulation of D1R in a monogamous primate, the titi monkey (Callicebus cupreus). Receptor binding of the D1R antagonist [11C]‐SCH23390 was measured in male titi monkeys using PET scans before and after pairing with a female. We found that within‐subject analyses of pairing show significant increases in D1R binding in the lateral septum, but not the nucleus accumbens, caudate, putamen, or ventral pallidum. The lateral septum is involved in a number of processes that may contribute to social behavior, including motivation, affect, reward, and reinforcement. This region also plays a role in pair bonding and paternal behavior in voles. Our observations of changes in D1R in the lateral septum, but not the nucleus accumbens, suggest that there may be broadly similar dopaminergic mechanisms underlying pair bonding across mammalian species, but that the specific changes to neural circuitry differ. This study is the first research to demonstrate neuroplasticity of the dopamine system following pair bonding in a non‐human primate; however, substantial variability in the response to pairing suggests the utility of further research on the topic.
Preparation of a temperature‐responsive smart paper using a molecularly imprinted polymer and lipid bimolecular membrane
Authors: Kawahara Yu , Ichiura Hideaki , Ohtani Yoshito
Published: October 2016

A smart paper that provided sustained release of benzalkonium chloride (BKC) at a set temperature was prepared. Filter paper impregnated with an oil‐in‐water emulsion containing BKC, methyl methacrylate monomer, ethylene diamine, and 2,2‐azobis(2,4‐dimethylvaleronitrile) was immersed in a cyclohexane solution of terephthaloyl chloride. A polyamide film containing the BKC MIP was formed on the paper surface via an interfacial polymerization reaction. Dimethlydistearylammonium bromide (DDB) was then coated over the polyamide film. The interfacial polymerization reaction eliminated the need for preparation of microcapsules of BKC or coating of the paper with a binder, which are methods commonly used for preparation of smart papers. Release of BKC from the paper was studied, and the temperature responses obtained with the DDB coating were evaluated. The smart paper with the BKC MIP and DDB coating showed sustained release of BKC, and this function was obtained in response to a certain temperature. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44530.
An ab initio Study of Excited States of C4H3 Radical
Authors: Choe Joong Chul , Kim Gap‐Sue
Published: October 2016

Carbon‐rich radicals are important for understanding chemistry of flames as well as astrochemistry. However, they are elusive for both experiments and computations, due to the peculiarity of radicals. Here, we calculated excited states of the 1‐buten‐3‐yn‐2‐yl (HCCCCH2
, i‐C4H3
) and n‐C4H3
(HCCCHCH) radicals with the state‐of‐the‐art complete active space self‐consistent field (CASSCF) and multi‐reference configuration interaction (MRCI) methods using the 6‐311 + G(3df,2p) and aTVZ basis sets. The vertical energies for the seven excited states of each of the two isomers were obtained with the MRCI method at the geometries optimized at the CASSCF/6‐311G(d,p) level. The result using the aTVZ basis set has been more reliable than predicted with the 6‐311 + G(3df,2p) basis set with the relative stability of the ground states of the two isomers better predicted in comparison to existing data. We believe that our results will be useful for understanding the chemistry of carbon‐rich radicals.
Fisher ruling requires buy‐in, thorough assessment of diversity, affirmative action
Authors: Porter Michael , Clausen Erica
Published: October 2016

Student‐body diversity is critically important to many institutions, and the U.S. Supreme Court has again ruled that diversity is critical enough in legal terms to be a “compelling government interest” and that certain forms of affirmative action to increase student‐body diversity can be constitutional.
Stay current on latest FERPA guidance, developments
Authors: Sutton Halley
Published: October 2016

PHOENIX — Maintaining up‐to‐date knowledge of the Family Educational Rights and Privacy Act can help you keep your institution in compliance.
Handbook provides latest safety and security reporting guidelines
Authors: Hope Joan
Published: October 2016

Meeting federal requirements for complying with the Jeanne Clery Disclosure of Campus Security Policy Act and other Higher Education Act safety and security reporting requirements is a critical part of your job.
Was a college liable for an independent contractor's alleged negligence?
Authors: Gelpi Aileen
Published: October 2016

Morehouse College hired Atlanta Audio Visual in 2011 to provide a concert stage for homecoming activities.
PA‐MSHA inhibits the growth of doxorubicin‐resistant MCF‐7/ADR human breast cancer cells by downregulating Nrf2/p62
Authors: Wei Yingze , Liu Danyang , Jin Xiaoxia , Gao Pan , Wang Qingying , Zhang Jiawen , Zhang Nong
Published: October 2016

Acquired resistance to doxorubicin in breast cancer is a serious therapeutic problem. In this study, we investigated whether Pseudomonas aeruginosa mannose‐sensitive hemagglutinin (PA‐MSHA) could inhibit the growth of doxorubicin‐resistant breast cancer cells. We found that the expressions of Nrf2 and p62 in breast cancer were higher than that in the corresponding adjacent normal tissues and benign breast epithelial cell. The expressions of Nrf2 and p62 in breast cancer doxorubicin‐resistant cells MCF‐7/ADR were higher than that in doxorubicin‐sensitive cells MCF‐7. Silencing of Nrf2 or p62 rendered breast cancer cells more susceptible to doxorubicin. We further demonstrated that PA‐MSHA inhibited growth and induced apoptosis of MCF‐7/ADR cells but not MCF‐7 cells. Subcutaneous administration of PA‐MSHA greatly inhibited the growth of xenograft tumors from MCF‐7/ADR cells in nude mice. In addition, PA‐MSHA could downregulate Nrf2 and p62 in vitro and in vivo. These results suggested that activation of Nrf2 and p62 was associated with doxorubicin resistance in breast cancer. PA‐MSHA could inhibit the growth of doxorubicin‐resistant MCF‐7/ADR cells and its potential mechanism might be due to the suppression of Nrf2/p62. It indicated the possibility of using PA‐MSHA in doxorubicin‐resistant breast cancer.
A theoretical review of consumer priming: Prospective theory, retrospective theory, and the affective–behavioral–cognitive model
Authors: Minton Elizabeth A. , Cornwell T. Bettina , Kahle Lynn R.
Published: October 2016

Primes are pervasive in marketing. Despite frequent use in practice, there has yet to be a framework to categorize priming techniques that is inclusive of measurement challenges and methods for administering primes as well as provides insight for researchers on how to think about and construct research using priming. Prior researchers have provided reviews of priming research, which have set the stage for discussions of priming theories and challenges of using primes in survey research. We build from their review and contribute in four ways by (i) reviewing priming theories rooted in both prospective and retrospective models of memory; (ii) developing a priming framework based on the ABC model of attitudes (affective, behavioral, and cognitive priming) that incorporates lexical priming, priming fluency effects, and methods for administering primes; (iii) addressing priming challenges including discrepancies between the priming method and measurement method; and (iv) positing the influence of personal characteristics on priming, such as the role of skepticism in assimilation and contrast effects. The final model is offered and elaborated upon as a guide for future research. Copyright © 2016 John Wiley & Sons, Ltd.
Enantioselective Intramolecular Reductive Heck Reaction with a Palladium/Monodentate Phosphoramidite Catalyst
Authors: Mannathan Subramaniyan , Raoufmoghaddam Saeed , Reek Joost N. H. , de Vries Johannes G. , Minnaard Adriaan J.
Published: October 2016

A palladium‐catalyzed enantioselective reductive Heck reaction of enones using monodentate phosphoramidite ligands is described. α,α,α’,α’‐tetraaryl‐1,3‐dioxolane‐4,5‐dimethanol (TADDOL)‐based phosphoramidites with palladium(II) acetate, and N‐methyl dicyclohexylamine as reducing agent gives the reductive Heck product in high yields and enantioselectivities of up to 90 %. The solvent plays an important role and in diethyl carbonate, the chemo‐ and enantioselectivity appeared to be the highest.
Structure‐Guided Redesign of CYP153AM.aq for the Improved Terminal Hydroxylation of Fatty Acids
Authors: Hoffmann Sara M. , Danesh‐Azari Hamid‐Reza , Spandolf Claudia , Weissenborn Martin J. , Grogan Gideon , Hauer Bernhard
Published: October 2016

The front cover artwork for Issue 20/2016 is provided by researchers from the Universität Stuttgart (Germany) and the University of York (United Kingdom). The image shows a free fatty acid substrate which drops into the active site of a P450 enzyme in an aqueous solution. The fatty acid is kept in the splash through the specific structural elements of the enzyme. See the Full Paper itself at http://dx.doi.org/10.1002/cctc.201600680.
Ubiquitin Associates with the N‐Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions
Authors: Lanza Valeria , Travaglia Alessio , Malgieri Gaetano , Fattorusso Roberto , Grasso Giuseppe , Di Natale Giuseppe , Zito Valeria , Arena Giuseppe , Milardi Danilo , Rizzarelli Enrico
Published: October 2016

Many biochemical pathways involving nerve growth factor (NGF), a neurotrophin with copper(II) binding abilities, are regulated by the ubiquitin (Ub) proteasome system. However, whether NGF binds Ub and the role played by copper(II) ions in modulating their interactions have not yet been investigated. Herein NMR spectroscopy, circular dichroism, ESI‐MS, and titration calorimetry are employed to characterize the interactions of NGF with Ub. NGF1–14, which is a short model peptide encompassing the first 14 N‐terminal residues of NGF, binds the copper‐binding regions of Ub (KD=8.6 10−5 m). Moreover, the peptide undergoes a random coil–polyproline type II helix structural conversion upon binding to Ub. Notably, copper(II) ions inhibit NGF1–14/Ub interactions. Further experiments performed with the full‐length NGF confirmed the existence of a copper(II)‐dependent association between Ub and NGF and indicated that the N‐terminal domain of NGF was a valuable paradigm that recapitulated many traits of the full‐length protein.
Investigation of Liner Systems in Transport of Organic and Inorganic Contaminants in Sanitary Landfill: A Case Study
Authors: Varank Gamze , Demir Ahmet , Adar Elanur , Bilgili Mehmet Sinan , Top Selin , Yazici Guvenc Senem , Ozcoban Mehmet Sukru
Published: October 2016

In the present work, a pilot‐scale study was carried out to investigate the diffusive transport of phenolic compounds and advective transport of heavy metals through liner systems composed of alternative materials and to evaluate the leachate effect on liner materials’ properties. For this purpose, ten pilot‐scale landfill reactors were operated for a period of about 290 days. Physico‐chemical, mineralogical composition, and geotechnical properties of liner materials were also reported. The results of the study suggest that performance of alternative liner systems have no significant difference in toxic organic contaminant attenuation and clay‐lime mixture were found to be the less effected liner system by leachate. Thereby clay‐lime mixtures can be effectively utilized as a component of landfill liners due to not only chemical, physical, and mineralogical properties but also their high abundance and low cost supply. A two‐layer liner system composed of clay‐lime mixture at the upper part and bentonite‐zeolite mixture at the lower part is recommended. Existence of lime at the upper part will provide improvement in soil properties and reduce leachate effects but will increase hydraulic conductivity by decreasing the thickness of diffuse double layer. A bentonite‐zeolite mixture existing at the lower part will provide adsorption of heavy metals and avoid heavy metal migration.
Multiscale Computational Study on the Adsorption and Separation of CO2/CH4 and CO2/H2 on Li+‐Doped Mixed‐Ligand Metal–Organic Framework Zn2(NDC)2(diPyNI)
Authors: Sokhanvaran Vahid , Yeganegi Saeid
Published: October 2016

The quantum mechanics (QM) method and grand canonical Monte Carlo (GCMC) simulations are used to study the effect of lithium cation doping on the adsorption and separation of CO2, CH4, and H2 on a twofold interwoven metal–organic framework (MOF), Zn2(NDC)2(diPyNI) (NDC=2,6‐naphthalenedicarboxylate; diPyNI=N,N′‐di‐(4‐pyridyl)‐1,4,5,8‐naphthalenetetracarboxydiimide). Second‐order Moller–Plesset (MP2) calculations on the (Li+–diPyNI) cluster model show that the energetically most favorable lithium binding site is above the pyridine ring side at a distance of 1.817 Å from the oxygen atom. The results reveal that the adsorption capacity of Zn2(NDC)2(diPyNI) for carbon dioxide is higher than those of hydrogen and methane at room temperature. Furthermore, GCMC simulations on the structures obtained from QM calculations predict that the Li+‐doped MOF has higher adsorption capacities than the nondoped MOF, especially at low pressures. In addition, the probability density distribution plots reveal that CO2, CH4, and H2 molecules accumulate close to the Li cation site. The selectivity results indicate that CO2/H2 selectivity values in Zn2(NDC)2(diPyNI) are higher than those of CO2/CH4. The selectivity of CO2 over CH4 on Li+‐doped Zn2(NDC)2(diPyNI) is improved relative to the nondoped MOF.
LMI‐based criterion for the robust guaranteed cost control of uncertain switched neutral systems with time‐varying mixed delays and nonlinear perturbations by dynamic output feedback
Authors: Ghadiri Hamid , Jahed‐Motlagh Mohammad Reza
Published: October 2016

This article reports on an investigation into robust guaranteed cost control (GCC) for uncertain switched neutral systems (USNSs) with interval time‐varying mixed delays and nonlinear perturbations via dynamic output feedback. Delay‐dependent sufficient conditions are suggested to guarantee the robust exponential stability and to obtain robust GCC for USNSs using the average dwell time approach and the piecewise Lyapunov function technique in terms of a set of linear matrix inequalities. The problem of uncertainty in the system model is solved by deploying the Yakubovich lemma. Lastly, two examples (i.e., a numerical example and the water‐quality dynamic model for the Nile River) are given to verify the efficiency of the propounded theories. © 2016 Wiley Periodicals, Inc. Complexity 21: 555–578, 2016