bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Information Systems Integration Project Using Rhapsody Engine (Preprint)
Authors: Kedwan Ftoon
Published: February 2022

UNSTRUCTURED

Background: This Health Information Systems’ (HIS) integration project reports a successful implementation experience of HIS integration with the pharmaceutical Pyxis system, that is used for medication dispensing. The Information Technology (IT) department in King Khalid Eye Specialist Hospital (KKESH) in Kingdom of Saudi Arabia led this project to its final successful deployment. Rhapsody Engine successful adoption in the integration process helped KKESH achieve their productivity goals by enhancing hospital’s staff daily duties and clinical workflow. It also eliminated the system’s errors and alerting notifications. Objective: This experience paper discusses three main questions: What is the power of systems integration? What are the systems’ integration standards? What are the main key performance indicators for ITD related projects? It also discusses the implemented solutions that solved many potential problems that could be encountered by similar big organizations such as the KKESH. Method: The adopted solution was implementing the Rhapsody integration engine to integrate HIS with Pyxis machines. Results: The hospital reported successful piloting implementation of this project. Some key lessons learned from this project experience are demonstrated and documented at the end of the paper.
Management of fetal Growth Restriction at term by Angiogenic Factors versus feto-maternal Doppler (GRAFD) to avoid adverse perinatal outcomes: multicenter open-label randomized controlled trial study protocol (Preprint)
Authors: Garcia-Manau Pablo , Mendoza Manel , Bonacina Erika , Martin-Alonso Raquel , Martin Lourdes , Palacios Ana , Sanchez Maria Luisa , Lesmes Cristina , Hurtado Ivan , Perez Esther , Tubau Albert , Ibañez-Burillo Patricia , Alcoz Marina , Valiño Nuria , Moreno Elena , Borrero Carlota , Garcia Esperanza , Lopez-Quesada Eva , Diaz Sonia , Broullon Jose Roman , Teixidor Mireia , Chulilla Carolina , Gil Maria M , Lopez Monica , Candela-Hidalgo Amparo , Salinas-Amoros Andrea , Moreno Anna , Morra Francesca , Vaquerizo Oscar , Soriano Beatriz , Fabre Marta , Gomez-Valencia Elena , Cuiña Ana , Alayon Nicolas , Sainz Jose Antonio , Vives Angels , Esteve Esther , Ocaña Vanesa , Lopez Miguel Angel , Maroto Anna , Carreras Elena
Published: February 2022

BACKGROUND

Fetal smallness affects 10% of pregnancies. These fetuses are at a higher risk of adverse outcomes. Their management using estimated fetal weight (EFW) and feto-maternal Doppler has a high sensitivity for adverse outcomes; however, more than 60% of fetuses are electively delivered at 37-38 weeks. On the other hand, the classification using angiogenic factors (AF) seems to have a lower false positive rate. Here we present a protocol for the GRAFD trial, which compares the management of small fetuses at term using AF or Doppler.

OBJECTIVE

The primary objective is to demonstrate that classification based on AF is not inferior to EFW and Doppler to detect fetuses at risk of adverse perinatal outcomes.

METHODS

This is a multicentre, open-label, randomized controlled trial conducted in 20 hospitals across Spain. A total of 1,030 singleton pregnancies with an EFW ≤10th percentile at 36+0 to 37+6 weeks will be recruited and randomly allocated to either the control or the intervention group. In the control group, standard Doppler-based management will be used. In the intervention group, cases with a soluble fms-like tyrosine kinase to placental growth factor ratio (sFlt-1/PlGF) ≥38 will be classified as fetal growth restriction (FGR), otherwise as small for gestational age (SGA). In both arms, FGR will be delivered at ≥37 weeks and SGA at ≥40 weeks. We will assess the differences between groups calculating the relative risks (RR) and their 95% confidence intervals.

RESULTS

The study is in the recruitment and data collection phase. The study results are expected to be published in peer-reviewed journals and disseminated at international conferences by the end of 2022 or in early 2023.

CONCLUSIONS

The AF-based protocol may reduce the number of pregnancies with classified as FGR without worsening perinatal outcomes. Moreover, reducing the number of unnecessary labor inductions would reduce costs and the risks derived from possible iatrogenic complications. Additionally, fewer inductions would lower the rate of early-term neonates, thus improving neonatal outcomes and potentially reducing long-term infant morbidities.

CLINICALTRIAL

NCT04502823
Community Health Worker-Led mHealth-Enabled Diabetes Self-management Education and Support Intervention in Rural Latino Adults: Single-Arm Feasibility Trial (Preprint)
Authors: Li Shiyu , Yin Zenong , Lesser Janna , Li Chengdong , Choi Byeong Yeob , Parra-Medina Deborah , Flores Belinda , Dennis Brittany , Wang Jing
Published: February 2022

BACKGROUND

Latinos living in rural South Texas have a higher prevalence of diabetes, but their access to diabetes self-management education and support (DSMES) is limited.

OBJECTIVE

We aimed to test the feasibility of a community health worker-led, mobile health (mHealth)-based DSMES intervention to reduce disparities in accessing DSMES in underserved rural Latino residents in South Texas.

METHODS

This 12-week, single-arm, pre-post trial was delivered by trained community health workers to 15 adults with type 2 diabetes. The intervention consisted of digital diabetes education, self-monitoring, a cloud-based connected platform, and community health worker support. Feasibility was evaluated as retention, actual intervention use, program satisfaction, and barriers to implementation. We also explored the intervention’s effect on weight loss and hemoglobin A1c (HbA1c).

RESULTS

All 15 participants were Latino (mean age 61.87 years, SD 10.67; 9/15 female, 60%). The retention rate at posttest was 14 of 15 (93%). On average, the participants completed 37 of 42 (88%) digital diabetes education lessons with 8 participants completing all lessons. Participants spent 81/91 days (89%) step tracking, 71/91 days (78%) food logging, 43/91 days (47%) blood glucose self-monitoring, and 74/91 days (81%) weight self-monitoring. The level of program satisfaction was high. On average, participants lost 3.5 (SD 3.2) kg of body weight (P=.001), while HbA1c level remained unchanged from baseline (6.91%, SD 1.28%) to posttest (7.04%, SD 1.66%; P=.668).

CONCLUSIONS

A community health worker-led mHealth-based intervention was feasible and acceptable to improve access to DSMES services for Latino adults living in rural communities. Future randomized controlled trials are needed to test intervention efficacy on weight loss and glycemic control.
COVID-19 anxiety and wellbeing at work: 3-wave longitudinal survey study (Preprint)
Authors: Oksanen Atte , Oksa Reetta , Celuch Magdalena , Cvetkovic Anica , Savolainen Iina
Published: February 2022

BACKGROUND

The uncertainty faced during the COVID-19 pandemic has been multifaceted. Consequently, many have experienced a prolonged state of negative psychological response caused by anxiety over the COVID-19 disease and the numerous virus variants that cause it.

OBJECTIVE

This longitudinal study analyzed risk and protective factors predicting COVID-19 anxiety among workers in Finland.

METHODS

Longitudinal sample of Finnish workers were surveyed during COVID-19 crisis in September–October 2020 (T1) and March-April 2021 (T2) and September–October 2021 (T3). 72.89% of the T1 respondents took part in both T2 and T3. Analysis included only those who were working during the follow-up (N = 798). Outcome measure was COVID-19 anxiety. Predictors were psychological distress, work exhaustion, technostress, and loneliness. Models also controlled for self-regulation, social support at work and remote working and socio-demographic background factors. Both within-person and between-person effects were analyzed using multilevel hybrid regression models.

RESULTS

COVID-19 anxiety varied between time points which is explained by the different pandemic situation during the time points, and highest anxiety was expressed in the middle of delta variant surge and lock-down in Spring 2021. Within-person changes in psychological distress, work exhaustion, technostress, self-regulation, and perceived loneliness were all associated with COVID-19-anxiety. Between-person results showed that distressed, exhausted, technostressed, and lonely workers expressed more anxiety than others. Remote workers reported also higher anxiety over time than others. Those who had reported high self-regulation reported lower anxiety than others. Female gender and younger age were associated with higher anxiety.

CONCLUSIONS

COVID-anxiety continues to be important phenomenon as pandemic has become more extensive than expected. General mental health and work stressors impact on COVID-19 anxiety. Promoting social support and workers self-regulation skills are beneficial for overcoming anxiety during and after pandemic.
Leksikon dalamTradisi Sib Mimnyen (Cacing Laut/Nyale) di Kabupaten Halmahera Tengah
Authors: Kamal Ashryani Sitinur M. , Cholsy Hayatul
Published: February 2022

This research was conducted to explore lexicon naming used in sib mimnyen tradition and the relationship with social values, community beliefs, and social activities. Data were collected using documentation techniques obtained from portraits of daily life and interviews with local communities. The research sample was randomly selected using random sampling technique. The results of this study found that the naming of nyale (marine worms) is influenced by several aspects such as language relation (Patani language in North Maluku - Thai Pattani language in Thailand), and the way of proccessing the worm, cognates vocabulary spesifically the sounds, and marine worm habitat. Furthermore, there were also non-language factors that supported determinism of sib mimnyen tradition consist of geographical location and social activities.

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Penelitian ini dilakukan dengan tujuan untuk menelisik penamaan leksikon yang digunakan dalam tradisi sib mimnyen dan hubungannya dengan nilai-nilai sosial, kepercayaan masyarakat, dan aktifitas sosial. Data dikumpulkan dengan menggunakan teknik dokumentasi yang diperoleh dari potret kehidupan sehari-hari dan wawancara terhadap masyarakat setempat. Sampel penelitian ini dipilih secara acak menggunakan teknik pengambilan sampel purposif. Hasil penelitian ini ditemukan penamaan nyale (cacing laut) dipengaruhi oleh beberapa aspek seperti hubungan kata antarbahasa (bahasa Patani Maluku Utara – bahasa Pattani Thailand), antarproses pengolahan, antarbunyi kosakata yang serupa (cognates vocabulary), dan habitat cacing laut. Selain itu, ditemukan juga faktor non bahasa yang menopang detrminasi budaya dalam tradisi sib mimnyen diantaranya letak geografis dan aktivitas sosial masyarakat.
Retensi dan Inovasi Fonologis Protobahasa Austronesia (Pan) pada Bahasa Sumbawa (Bs)
Authors: Wahid Mardiah Husnul Fitri
Published: February 2022

Penelitian ini bertujuan mendeskripsikan fonem PAN yang mengalami retensi dan inovasi fonologis pada bahasa Sumbawa (BS) ditinjau dari persepektif diakronis. Data yang digunakan sebanyak 200 kosakata. Pengumpulan data lapangan dilakukan dengan metode simak dan cakap dengan teknik catat dan rekam, metode cakap semuka dengan menggunkan teknik dasar pancing dengan teknik bawahan catat, dan rekam. Data dianalisis dengan menerapkan metode kualitatif deduktif dengan menggunakan metode inovasi bersama dan metode komparatif. Hasil penelitian secara diakronis menunjukkan empat vokal mengalami retensi yaitu /i/, /u/, /a/, /e/, dan  terdapat 15 fonem konsonan yang mengalami reesi yaitu /p/, /b/, /t/, /d/, /k/, /g/, /m/, /n/, /ŋ/, /ñ/, /s/, /r/, /l/, /w/, /y/. Sedangkan untuk fonem PAN yang mengalami inovasi pada BS terdapat beberapa fonem, yang mana beberapa fonem inovasi teratur dan tidak teratur (sporadis). Adapun fonem PAN yang mengalami inovasi tidak teratur atau sporadis yaiu *i > e, *u > o, *b > p,w, dan *ə > ə, e, ɛ. sedangkan inovasi teratur fonem PAN pada BS yaitu *z > j, *j > d, t, *w > ø, dan *y > ø, inovas kerap terjadi pada posisi awal dan antarvokal pada BS.
Alokasi Resource bagi Multicarrier-Low Density Sequence-Multiple Access
Authors: Linda Meylani  , Nur Andini  , Desti Madya Saputri  , Iswahyudi Hidayat
Published: February 2022

Multicarrier low-density sequence multiple access (MC-LDSMA) merupakan salah satu tipe dari non-orthogonal multiple access (NOMA) domain kode pada sistem multicarrier. Setiap pengguna (user) pada skema akses ini memiliki kode yang tidak ortogonal satu dengan lainnya, dengan setiap pengguna hanya mengakses sejumlah dv resource dari N resource yang tersedia dan hanya terdapat dc pengguna dari total J pengguna yang mengakses resource yang sama. Sifat nonortogonal ini menyebabkan sistem MC-LDSMA memiliki overloading factor yang lebih tinggi dibandingkan sistem multicarrier ortogonal lainnya. Kondisi ini mengakibatkan MC-LDSMA menjadi salah satu teknik akses jamak yang dapat digunakan pada sistem komunikasi radio kognitif underlay, dengan sejumlah pengguna sekunder (secondary user, SU) atau unlicensed user diberikan izin untuk mengakses resource yang dimiliki oleh pengguna primer (primary user, PU) atau licensed user. Makalah ini mengusulkan algoritme alokasi resource bagi MC-LDSMA pada sistem radio kognitif underlay. Algoritme yang diusulkan bertujuan meningkatkan jumlah SU yang mengakses resource PU sekaligus menjaga faktor kualitas SU. Sistem yang dibangun terdiri atas sejumlah I pengguna PU dan J pengguna SU. Pengguna PU pada sistem diasumsikan saling ortogonal sehingga tidak saling menginterferensi satu dengan lainnya, sedangkan sejumlah J SU mengakses resource yang dimiliki PU secara bersamaan dengan menggunakan skema akses jamak MC-LDSMA. Algoritme usulan memperhatikan beberapa faktor, di antaranya parameter dc, dv, signal-to-noise ratio (SNR) target SU, dan batas toleransi interferensi yang dikehendaki oleh PU. Parameter kinerja ditunjukkan oleh outage probability (OP), throughput PU dan SU, dan rasio jumlah SU yang mendapatkan alokasi kurang dari dv resource. Hasil simulasi menyatakan bahwa semua parameter kinerja dipengaruhi oleh jumlah resource yang diakses oleh setiap pengguna, dv. SNR target SU dan batas interferensi yang ditentukan PU akan memengaruhi nilai OP, throughput rata-rata SU dan PU, serta jumlah SU yang tidak mendapatkan dv resource.
Kinerja Konvolusi pada Sistem Amplify and Forward dengan Predistorsi dan Seleksi Relai
Authors: Annisa Anggun Puspitasari  , Mareta Dwi Nor Habibah  , Ziyadatus Shofiyah  , Ida Anisah  , Yoedy Moegiharto
Published: February 2022

Pada makalah ini dilakukan evaluasi kinerja teknik pengodean konvolusi pada sistem komunikasi kooperatif dengan protokol amplify-and-forward (AF) dan menerapkan strategi seleksi relai dengan simulasi. Di sisi pemancar (sumber) diterapkan gabungan teknik reduksi peak to average power ratio (PAPR) skema selective mapping (SLM) dan predistorsi model Hammerstein. Di relai diterapkan juga teknik predistorsi model inverse Rapp. Di sisi kanal digunakan relai sebagai antena virtual. Penggunaan relai dalam sistem komunikasi kooperatif dapat diimplementasikan untuk jaringan 4G atau 5G pada penelitian selanjutnya, tetapi tentu membutuhkan bandwidth yang besar. Penerapan strategi seleksi relai mampu meningkatkan efisiensi bandwidth karena hanya relai terbaik saja yang akan meneruskan informasi dari pengirim ke penerima. Strategi seleksi relai jenis konvensional digunakan untuk mengevaluasi kinerja teknik pengodean konvolusi pada skema multirelai dengan memilih sebuah relai terbaik yang mempertimbangkan nilai signal to noise ratio (SNR) pada kanal sumber ke relai dan relai ke tujuan. Relai terbaik tersebut akan meneruskan sinyal dari sumber ke tujuan dengan menggunakan protokol AF. Kinerja sistem dinyatakan dalam nilai probabilitas bit error rate (BER). Dari hasil simulasi, dapat ditunjukkan bahwa teknik pengodean konvolusi mampu memperbaiki kinerja sistem hingga mencapai 16,59%, baik dengan menggunakan teknik predistorsi maupun tanpa teknik predistorsi. Kemudian, penerapan teknik predistorsi di sisi sumber dan relai mampu menghasilkan kinerja paling baik, yaitu kinerja sistem dapat meningkat hingga mencapai 34%. Selain itu, penerapan strategi seleksi relai jenis konvensional menunjukkan bahwa skema dengan relai terbanyak, yaitu enam relai, mampu menghasilkan kinerja yang paling baik disebabkan semakin banyaknya pilihan jalur yang tersedia.
Analisis Kinerja Aplikasi Pemantauan dan Pengendalian Smart Agriculture Berbasis Android
Authors: Helmy  , Fenny Rahmasari  , Arif Nursyahid  , Thomas Agung Setyawan  , Ari Sriyanto Nugroho
Published: February 2022

Era digital yang terus berkembang melahirkan revolusi industri budidaya pertanian dan peternakan cerdas berbasis internet of things (IoT). Salah satunya adalah penggunaan aplikasi berbasis Android dalam pemantauan dan pengendalian parameter pada proses budidaya di era digital ini. Koneksi internet yang tidak stabil dapat mengganggu proses pemantauan. Oleh karena itu, diperlukan pengintegrasian sistem dalam satu aplikasi yang dapat berjalan walaupun dalam keadaan internet terputus (offline), sehingga pengelola dapat melakukan pemantauan dan pengendalian smart agriculture berbasis Android dengan dua mode operasi, yaitu online dan offline. Analisis kinerja juga diperlukan untuk mengetahui keandalan aplikasi dalam pengiriman dan penerimaan data. Integrasi sistem ini menggunakan dua mode, yaitu mode operasi online dan offline. Mode online mengindikasikan aplikasi Android berinteraksi dengan sistem melalui server ketika terkoneksi dengan internet menggunakan metode representational state transfer application programming interface (REST API), sedangkan mode offline artinya aplikasi Android berinteraksi langsung dengan sistem melalui koneksi local device (access point/AP lokal). Smart agriculture berinteraksi dengan sistem melalui protokol message queuing telemetry transport (MQTT), dengan Android bertindak sebagai client MQTT. Analisis kinerja aplikasi meliputi pengujian black box, load activity, dan kinerja aplikasi melalui fitur profiler Android. Hasil yang diperoleh berdasarkan pengujian fungsionalitas aplikasi (black box) menunjukkan bahwa aplikasi dapat memantau dan mengendalikan smart agriculture dengan baik secara online maupun offline oleh pengelola. Nilai load time rata-rata di seluruh aktivitas sebesar 3,507 detik saat bandwidth sebesar 4,54 Mbps. Sementara itu, rata-rata load time yang dihasilkan saat bandwidth 35,35 Mbps adalah sebesar 1,4 detik. Berdasarkan pengujian kinerja, sistem ini cukup ringan dengan penggunaan central processing unit (CPU) terbesar 31% dan penggunaan memori terbesar 453,8 MB.
Hydrologic data base Management Analysis of Small Islands in the River Region of Maluku
Authors: Talakua Silwanus M , Nara Obednego D
Published: February 2022

In order to optimize and develop water resource management, accurate data is needed for regional development. The data is compiled in the form of a database which is a support for the development of the water resource potential of small islands in Maluku River Region. The purpose of this study is to display a database of infrastructure in the form of Rainfall Posts, Climatology Posts, Water estimation posts, pond distribution data, weir distribution data and water quality in Ambon-Seram, Buru, Kei-Aru Islands and Yamdena-Wetar Islands by using the ArcGIS application. The result of the database is a supporting tool in the managing Hydrology and data at Maluku River Region Hall by providing information in the form of graphical data and distribution map.
Convergence in infant mortality rates: the Spanish regions case
Authors:   Universidad de Zaragoza, Martínez-Asenjo Cristina , Montañés Antonio ,   Universidad de Zaragoza
Published: February 2022

This paper studies the evolution of infant mortality rates in Spanish regions. Our results allow us to reject the null hypothesis of convergence, but we find the presence of several convergence clubs, which implies the existence of different patterns of behavior. We also find some degree of connection between the Great Recession and the evolution of infant mortality rates. The popula-tion density, the evolution of the labor market and the percentage of the female population that admits to having drunk alcoholic beverages in the previous two weeks are the factors that help us to explain the forces that drive the creation of the clubs.
The Hispanic immigration in United States: an analysis of the relationship with the churches, employment and crime
Authors:   Universidad de Valladolid, Valero-Matas Jesús Alberto , Sánchez-Bayón Antonio ,   ISEMCO-Universidad Rey Juan Carlos
Published: February 2022

The aim of this paper is to show the relationship among the Hispanic immigration (mostly with an irregular citizen status) in US (some areas where they live many Hispanic) and the churches that are linked to these communities. The undocumented Hispanics are being persecuted, de-ported and in the elections talk down them to win votes. Only in their confessions have they have found the most stable refuge for a long time due to during the past two decades, churches become in the main upholder and protector of the Hispanic community in the United States. Thus, this research explores the ramifications and the pillars of this outstanding relationship that had been built through time. This paper also analyzes the relationship between the labor market and unauthorized immigration, as it is attributed to unauthorized immigrants to be the cause of unemployment of the natives. As well as being criminals and the main inhabitants of prisons. Reality that is far from reality. The Trump Administration, following many of the thoughts of some American citizens, maintains the accusation towards Hispanic immigration of working illegally in the country, as well as increasing crime.Keywords: Unauthorized immigration, congregations, Hispanic, labor market, crime.ResumenEste trabajo intenta analizar la relación entre la inmigración hispana (principalmente aquellos con un estatus de ciudadano irregular y en áreas donde residen muchos hispanos) en los Estados Unidos y las iglesias que están vinculadas a estas comunidades. Los hispanos indocumentados están siendo perseguidos, deportados y en las campañas electorales son criticados con el objetivo de ganar votos. Prácticamente, durante mucho tan sólo en sus confesiones han encontrado el refugio, pues en las últimas dos décadas, las iglesias se convirtieron en el principal defensor y protector de la comunidad hispana en los Estados Unidos. Por lo tanto, esta investigación explora las ramificaciones y los pilares de esta relación sobresaliente que se ha construido a través del tiempo. Pero también se aborda la cuestión del mercado laboral, pues se atribuye a los inmigrantes no-autorizados ser los causantes del desempleo de los nativos. Como también de ser delincuentes y los principales habitantes de las cárceles. Realidad que dista mucho de ello. La Administración de Trump, siguiendo muchos de los pensamientos de algunos ciudadanos norteamericanos, mantiene la acusación hacia la inmigración hispana de trabajar ilegalmente en el país, así como de incrementar la delincuencia. Palabras clave: Inmigración no autorizada, congregaciones, hispanos, mercado laboral, delin-cuencia.
Screening and Isolation of Bacteria Producing Biosurfactants from Waste
Authors: Shagufta Shaikh M , Dharani P.V.
Published: February 2022

Biosurfactant are surface active compounds (SAC), amphiphilic in nature consisting of hydrophobic (long chain fatty acids) and hydrophilic domain (amino acid, protein, carbohydrate). Classification of this compound is based on molecular weight, mode of action and physico-chemical structure. Biosurfactant are being utilized in laundry formulation, house hold cleaning products, as antimicrobial agents, in detergents, pesticides, food and pharmaceutical industries. Various type of microorganism has been studied capable of synthesizing wide range biosurfactant by utilizing hydrocarbon compounds as source of carbon and energy. Present study aims to isolate biosurfactant producing bacteria from different waste sources. In this study among twenty-one isolated microbial cultures from different waste samples were screened for biosurfactant production using methods like hemolytic activity, blue gar assay, hydrocarbon tolerance assay, oil spread test, Emulsification index (E24%).
Scrub Typhus: An Emerging Etiology among Undiagnosed Febrile Cases in Western Part of Uttar Pradesh, India
Authors: Sultan Asfia , Shuaib Afaf , Rizvi Meher , Khan Fatima , Chaudhry Rama , Thakur Chandan Kumar
Published: February 2022

Scrub typhus is a re-emerging zoonotic rickettsial disease and is prevalent in many parts of India. Scrub typhus in Uttar Pradesh is virtually unknown but has shown emergence in recent reports. In this context, a prospective study was planned to analyze the prevalence and clinic-epidemiological parameters of scrub typhus in febrile patients present in JNMC hospital. Patients of >15 years with undiagnosed acute febrile illness of more than 5 days with or without acute respiratory failure and acute renal failure (ARF) were included in the study. Clinical profile was recorded through predesigned proforma. Blood samples were collected and serological tests were performed. PCR was performed on whole blood samples of positive patients. Total 414 patients, who were negative for other common febrile etiologies, i.e.: malaria, dengue, enteric fever were included in the study. Out of 414 patients, 112 (27%) were found positive for scrub typhus by ELISA and micro-immunofluorescence (MIF). PCR was negative in all cases. Slight male predominance (52.6%) was observed. Significant number of positive cases 90(80.3%) were between 18-46 years of age (P value <0.05). Majority of cases appeared during winter season Respiratory involvement was significant in positive cases (P value <0.05). Among the gastro-intestinal symptoms, diarrhea and vomiting were also significant (P value <0.005). All the patients responded to the treatment. No complications and mortality was observed. Scrub typhus should be considered in undiagnosed febrile patients coming from rural and agricultural background with respiratory and gastrointestinal symptoms. Serology is reliable in the diagnosis of scrub typhus as molecular testing is costly, labor intensive and not helpful.
Comparison of Survival of Healthcare Associated Bacteria on Materials used for Making White Coat
Authors: Thomas Silla Varghese , Bhat K. Gopalakrishna
Published: February 2022

Healthcare-Associated Infections (HAIs) are of global concern in this present era and white coats play an important role in the transmission of HAIs. The most common healthcare-associated bacteria are Enterococcus species, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanni, Pseudomonas aeruginosa and Enterobacter species (ESKAPE bugs). These healthcare-associated bacteria are capable of surviving on white coats which could act as fomites in the transmission of HAIs. The purpose of this study was to compare the duration of survival of healthcare-associated bacteria on different materials used for making white coats. Materials like pure cotton, artificial cotton, cotton silk, spun and crepe were cut into swatches of 1cm2 size and sterilized by autoclaving. Five different bacteria isolated from clinical specimens were grown on 5 % sheep blood agar and bacterial suspensions were made in sterile physiological saline. The swatches were immersed in bacterial suspension and kept in petri plates at 25°C. The viable counts of bacteria were determined at definite time intervals by surface plate method. The present study shows that among the healthcare-associated bacteria, S.aureus survived the maximum up to 52 days. The duration of survival of S.aureus was significantly longer than P.aeruginosa and A.baumannii (p <0.05). A.baumannii survived only up to 20 days maximum. All the healthcare-associated bacteria significantly survived for the shortest duration of time on crepe. Therefore, crepe could be a better material used for making white coats.
Isolation and Identification of Biofilm-Producing, Drug-Resistant Coagulase Negative Staphylococci from a Hospital Environment in Northern Philippines
Authors: Espiritu Allan Jay C. , Villanueva Sharon Yvette Angelina M.
Published: February 2022

Healthcare-associated infections (HCAIs) are considered adverse outcomes of confinement in a healthcare facility. Biofilm-producing, drug-resistant bacteria have further aggravated the problem with HCAIs. This study determined the prevalence, antibiotic susceptibility, and biofilm phenotype of coagulase-negative staphylococci (CoNS) isolated from a hospital environment in Northern Philippines. The identification of CoNS species and the determination of antibiotic susceptibility were done using an automated assay. Biofilm production was detected using tissue culture plate (TCP) and Congo red agar (CRA) methods. Out of 220 surfaces and 26 air samples collected, 103 (41.9%) CoNS strains were isolated, predominated by S. epidermidis with 30.1% prevalence. The medical ward was found to have the highest prevalence of CoNS at 64%. The CoNS isolates exhibited a variable resistance profile; the highest was found against penicillin (97.1%) and oxacillin (54.3%). Isolates manifesting resistance to linezolid and vancomycin were also detected. From the 103 CoNS isolates, 52 (50.5%) biofilm producers were detected using the TCP method, and 39 (37.9%) were detected by the CRA method. Statistically significant difference was found between the biofilm biomass and the slime-producing pattern. This study revealed the prevalence of biofilm-producing, drug-resistant strains of CoNS in a Level 3 hospital in Northern Philippines. This warrants further enhancement of infection prevention and control programs to avert the emergence of more biofilm-producing, drug-resistant bacterial strains that could pose formidable threats to public health.
Occurrence and Resistance Pattern of Gram-Negative Bacteremia and Sepsis in A Tertiary Care Hospital - A Four-Year Study
Authors: Juliana Alamu , Leela K.V. , Gopinathan Anusha , Sujith R.
Published: February 2022

The rise in antibiotic resistance has been a major source of public health concern. As a result, mortality and morbidity rates have risen significantly. This study was done to identify gram-negative organisms causing bacteremia/sepsis, study their prevalence rates, and antimicrobial resistance patterns, as evidence-based knowledge of gram-negative organisms causing sepsis and their resistance profiles is essential for effective hospital control and better management of infections caused by resistant bacteria. A retrospective study, conducted from January 2016 to December 2019, blood samples were collected using aseptic guidelines and cultured using automated blood culture methods. Biochemical tests were done according to microbiology standard procedures, while antimicrobial testing was done according to CLSI guidelines. A total of 13,808 blood samples were received within the study period of four years. Of the total, 2079 showed significant growth, with 765 being GNB isolates. The most common isolates were Escherichia coli (35.42%), Klebsiella pneumonia (19.74%), Acinetobacter species (9.67%), and other non-fermenting gram-negative bacilli (11.76%). Escherichia coli showed yearly resistance to aminoglycosides, cephalosporins, penicillin, fluoroquinolones, and B-lactam combination agents. Routine surveillance and awareness of the prevalence, etiological agents, and antibiotic resistance of gram-negative bacteria causing bacteremia/sepsis is critical for individual therapy, hospital control, and the effectiveness of preventive interventions.
Point Prevalence Survey of Antimicrobial Utilization in a Tertiary Care Teaching Hospital and a Comprehensive Comparative Analysis of PPS across India
Authors: Nirula Suvansh , Nabi Nusrat , Ali Mohammad Daud , Ray Arunabha , Mustafa Ajaz , Husain Musharraf , Kapur Pranay , Mukherjee Shoma , Aggarwal Sanjana
Published: February 2022

This study assessed antimicrobial prescription at our institute to promote rational antimicrobial use and implement customized antimicrobial stewardship programs. This study is a cross sectional point-prevalence survey on antimicrobial utilisation conducted at HAH Centenary hospital, New Delhi in April, 2019, over a period of 3 days. All in-patients were included in the analysis. However, neonates, emergency room patients and palliative care patients, orders for anti-viral, anti-fungal, anti-tubercular and anti-parasitic medications were excluded. SPSS version 13.0 was planned to be used for analysis of the statistical data. The number of patients admitted at the point of time of our survey was 217, out of which 101 (46.54%) patients were receiving antimicrobial agents (AMA) with 160 (73.73%) AMAs prescribed. 50 patients (49.5%) were prescribed AMAs for infections, whereas, 49 patients (48.51%) were prescribed AMAs prophylactically and 2 (1.98%) patients received AMAs for reasons not defined. The intensive care units exhibited 93.33% patients receiving antimicrobials. The most common indication was intra-abdominal infections (32.40%). The most commonly used antibiotics were beta-lactam antibiotics (60.62%). The study suggests a high rate of antimicrobial use and highlights areas for intervention for rational antimicrobial use. We propose to sensitise the government on initiating a national antimicrobial stewardship program such as the Global Point Prevalence Survey and facilitate evidence-based antimicrobial practice.
Green Approach for the Synthesis of Copper Oxide Nanoparticles and its Antibacterial Effect against Methicillin-resistant Staphylococcus aureus (MRSA)
Authors: Majeed Shahnaz , Shukhairi Ahmad Najmi Bin , Danish Mohammed
Published: February 2022

Nowadays, nanotechnology has gained promising advantages in the medical and pharmaceutical field by improving the delivery of drug to the target site. Morinda citrifolia L. belongs to the genus Morinda of the family Rubiaceae and know as ‘Pokok Mengkudu’ in Malay. Aqueous extract of Morinda citrifolia treated with copper (II) sulfate results in the formation of copper oxide nanoparticles. The size of synthesized copper oxide nanoparticles (CuONPs) was 10-30nm spherical in shape using TEM analysis. UV spectrophotometer showed the absorption peak at 306nm. SEM analyses confirm the surface morphology of nanoparticles showed spherical shaped particles. FTIR spectroscopy showed broad absorption bands between 2800 and 4000 cm−1 showed C-O, OH, C=O stretch are associated with nanoparticles. Zeta potential showed the value of 21.8 mV and -6.45 mV confirms the stability of nanoparticles. These CuONPs showed good antibacterial activity against Staphylococcus aureus (ATCC 33591) 20mm, Staphylococcus epidermidis (ATCC 35984) 16 mm, Salmonella typhi, 17mm Escherichia coli (ATCC 25922) 18mm and Vibrio cholerae 20mm. CuONPs also had significant antibacterial properties against Methicillin-resistance Staphylococcus aureus (MRSA) (ATCC 4330). These CuONPs also show good synergistic affect along with Ceftriaxone, Gentamycin and Amoxicillin antibiotic against bacterial pathogens respectively.
Mathematical analysis of a Markovian multi-server feedback queue with a variant of multiple vacations, balking and reneging
Authors: Bouchentouf Amina Angelika , Medjahri Latifa , Boualem Mohamed , Kumar Amit
Published: February 2022

In this paper, we analyze a multi-server queue with customers impatience and Bernoulli feedback under a variant of multiple vacations. On arrival, a customer decides whether to join or balk the system, based on the observation of the system size as well as the status of the servers. It is supposed that customer impatience can arise both during busy and vacation period because of the long wait already experienced in the system. The latter can be retained via certain mechanism used by the system. The feedback occurs as returning a part of serviced customers to get a new service. The queue under consideration can be used to model the processes of information transmission in telecommunication networks. We develop the Chapman-Kolmogorov equations for the steady-state probabilities and solve the differential equations by using the probability generating function method. In addition, we obtain explicit expressions of some important system characteristics. Different queueing indices are derived such as the probabilities when the servers are in different states, the mean number of customers served per unit of time, and the average rates of balking and reneging.
Finite-difference methods for solving 1D Poisson problem
Authors: Ndayisenga Serge , Sevastianov Leonid A. , Lovetskiy Konstantin P.
Published: February 2022

The paper discusses the formulation and analysis of methods for solving the one-dimensional Poisson equation based on finite-difference approximations - an important and very useful tool for the numerical study of differential equations. In fact, this is a classical approximation method based on the expansion of the solution in a Taylor series, based on which the recent progress of theoretical and practical studies allowed increasing the accuracy, stability, and convergence of methods for solving differential equations. Some of the features of this analysis include interesting extensions to classical numerical analysis of initial and boundary value problems. In the first part, a numerical method for solving the one-dimensional Poisson equation is presented, which reduces to solving a system of linear algebraic equations (SLAE) with a banded symmetric positive definite matrix. The well-known tridiagonal matrix algorithm, also known as the Thomas algorithm, is used to solve the SLAEs. The second part presents a solution method based on an analytical representation of the exact inverse matrix of a discretized version of the Poisson equation. Expressions for inverse matrices essentially depend on the types of boundary conditions in the original setting. Variants of inverse matrices for the Poisson equation with different boundary conditions at the ends of the interval under study are presented - the Dirichlet conditions at both ends of the interval, the Dirichlet conditions at one of the ends and Neumann conditions at the other. In all three cases, the coefficients of the inverse matrices are easily found and the algorithm for solving the problem is practically reduced to multiplying the matrix by the vector of the right-hand side.
Optimalisasi Masyarakat Desa Lubok Batee dalam Menghadapi Tanggap Darurat Pandemi Covid-19
Authors: Safitri Risna , Muslem
Published: February 2022

This community service aims to provide education and socialization in understanding the dangers, prevention, transmission, and how to break the chain of the spread of covid-19. The method used in this community service is in education and socialization of a clean and healthy lifestyle to anticipate the spread of Covid-19 by distributing masks, making hand sanitizer s, washing clean and correct hands, and doing healthy exercise. The result of this community service activity is that residents gain knowledge through the education and socialization stages in distributing free masks, making hand sanitizer s, and washing their hands clean and properly. The implementation of education and outreach encourage residents of Lubok Batee Village practicing a clean and healthy lifestyle. They understand how to use masks, provide hand washing facilities, avoid direct contact with other residents, comply with health protocols, know the types of disposable masks and types of re-wash masks. Furthermore, they have better understanding the lifestyle patterns and behaviors in society by consuming healthy foods in a balanced manner.
DIREITOS DOS IMIGRANTES MERCOSULINOS NO BRASIL
Authors: De Moura Aline Beltrame , Dalri Luciene
Published: February 2022

A Constituição da República Federativa do Brasil, de 1988, promoveu a abertura da política migratória brasileira, tornando inválidos vários dispositivos restritivos previstos no então Estatuto do Estrangeiro (1980). Paralelamente à normativa nacional sobre o direito dos imigrantes, foi adotado, no âmbito do processo de integração mercosulino, o Acordo sobre Residência para os Nacionais dos Estados Partes do Mercosul em 2002, o qual prevê uma série de direitos e prerrogativas aos nacionais de qualquer um desses Estados, que decida fixar residência em outro Estado signatário. A recepção do acordo pelo Brasil criou a expectativa, em âmbito nacional, de ampliação de direitos e de maior humanização ao tratamento do estrangeiro mercosulino. Considerando as diferentes previsões normativas sobre a temática dos imigrantes no Brasil, este artigo pretende realizar um confronto entre os direitos previstos no ordenamento jurídico brasileiro e no citado Acordo do Mercosul. O intuito é verificar por meio do método comparativo sincrônico em que medida o Acordo sobre Residência inova em relação à Constituição da República Federativa do Brasil, de 1988 e em que situações simplesmente repete disposições consagradas não apenas na constituição, mas também na doutrina e na jurisprudência. Mediante este estudo, foi possível observar que o Brasil apresenta historicamente grande reconhecimento de direitos ao estrangeiro, ao mesmo tempo em que denota a pouca inovação proporccionada pelo Acordo sobre Residência para Nacionais dos Estados Partes do MERCOSUL.
IMPEACHMENT E RESPONSABILIDADE JURÍDICA
Authors: Resende Ranieri L.
Published: February 2022

Visa o artigo à análise do impeachment em sua posição de mecanismo de controle institucional de agentes políticos, a partir da busca por suas bases teórico-históricas oriundas do common law. O enfrentamento do problema da definição da(s) natureza(s) do impeachment objetivou, em primeiro lugar, situar a questão da responsabilidade na abrangência teórica da democracia representativa, face às falhas que lhe são imanentes com relação a desvios de expectativas e abusos de poder. Ao identificar distinções estruturais entre as responsabilidades política (accountability) e jurídica, configurou-se adequado resgatar historicamente o requisito da violação de lei nos precedentes atenienses clássicos (eisangeliai). As mutações sequenciais vinculadas ao impeachment perpassaram as fases de: a) estabelecimento de parâmetros procedimentais (primeiros casos); b) exigência do critério de juridicidade (período Stuart); c) busca por especificação das hipóteses de cabimento (EUA); d) fixação de tipos legais precisos de violação (Brasil). Sob o prisma histórico-comparado, evidenciou-se nítido o crivo de juridicidade qualificada adotado no primeiro modelo normativo do impeachment presidencial brasileiro (1891-1892).
HORIZONTE DA PROTEÇÃO INTERNACIONAL DE DIREITOS HUMANOS EM DIMENSÃO CULTURAL
Authors: Marques Clarissa , Afonso Henrique Weil , Da Silva Filho Lúcio Marcos
Published: February 2022

O presente trabalho de investigação tem por objetivo problematizar a interação entre a matriz teórica do Novo Constitucionalismo Latino-Americano e a proteção internacional de direitos humanos. O problema da limitação ou da promoção das autonomias das comunidades originárias ganha relevo na medida em que a transformação em curso no constitucionalismo andino reforça concepções de direito e de jurisdição horizontais, pautadas no diálogo intercultural e na construção da plurinacionalidade, consubstanciando tanto inovações institucionais e normativas quanto rupturas face a modelos legais incompatíveis com as premissas do pensamento decolonial. O trabalho insere-se no gênero teórico e emprega metodologia dedutiva. A partir de um diálogo com a obra de pensadoras e pensadores decoloniais, indaga-se sobre os pressupostos de uma jurisdição restauradora de histórias como forma de engajamento permanente, plural e dialógico entre múltiplas instâncias jurisdicionais.
CONSTITUIÇÃO VERSUS CIDADANIA:
Authors: Casamasso Marco
Published: February 2022

Resumo: O artigo visa a oferecer elementos para a reflexão em torno da complexa relação entre cidadania e Constituição. Em contraste com os enfoques jurídicos tradicionais, o presente estudo privilegia as ambiguidades, tensões e conflitos que ocorrem entre, de um lado, as demandas pela garantia e ampliação dos direitos de cidadania, e, de outro, a Constituição. Considerada a sua relevância no cenário do constitucionalismo moderno, optou-se por delimitar o objeto da investigação à experiência constitucional norte-americana. Desenvolveu-se a proposta de trabalho em três etapas. Inicialmente, propõe-se uma crítica à perspectiva jurídica da cidadania, destacando-se as suas limitações em face das reivindicações e disputas sociais pela ampliação de direitos fundamentais. Em seguida, põe-se em evidência o eventual antagonismo entre Constituição e a cidadania. A etapa derradeira envolve a apresentação de aspectos da Constituição dos Estados Unidos refratários à cidadania, e uma exemplificação de decisões injustas da Suprema Corte norte-americana, em detrimento dos cidadãos. A despeito da sua relevância, é escassa a produção acadêmica dedicada à problemática do antagonismo entre Constituição e cidadania.
FAKE NEWS NA ERA DIGITAL E A AUSÊNCIA DE POLÍTICAS PÚBLICAS DE EDUCAÇÃO PARA O USO DAS TIC’S
Authors: Parchen Charles Emmanuel , Freitas Cinthia Oblande de Almendra , Cavalli Tássia Teixeira de F.B.E
Published: February 2022

Pelo método indutivo e pelo procedimento da coleta empírica de dados e com apoio da revisão bibliográfica, da pesquisa exploratória e descritiva, o estudo objetiva discutir a prática das denominadas Fake News no ambiente político e digital brasileiro, para alertar acerca da necessidade de adoção de políticas públicas governamentais que priorizem a educação para o uso das tecnologias, pois é na ausência de educação para o uso das tecnologias das TICs que as Fake News encontram um cenário ideal para se propagar. Conclui o artigo que a educação para o uso das tecnologias como política pública é a forma mais eficiente de se atender ao princípio da dignidade da pessoa humana e também de promoção dos direitos fundamentais de liberdade individual, pois só assim haverá a ocorrência da verdadeira inclusão digital, alcançada com a emancipação do ser humano através do processo educacional.

Pelo método dedutivo e da pesquisa exploratória e descritiva, o estudo tem por escopo discutir a prática das denominadas fake news, especialmente no ambiente político e digital brasileiro, para alertar acerca da necessidade de adoção de políticas públicas governamentais que priorizem a educação para o uso das tecnologias ao invés de impor meras sanções pecuniárias a pessoas ou empresas que disseminem falsas informações. Com efeito, é na ausência de educação para o uso das tecnologias das TIC’s que as fake news encontram um cenário ideal para se propagar. Conclui o artigo que a educação para o uso das tecnologias como política pública é a forma mais eficiente de se atender ao princípio da dignidade da pessoa humana e também de promoção dos direitos fundamentais de liberdade individual, pois só assim haverá a ocorrência da verdadeira inclusão digital, alcançada com a emancipação do ser humano através do processo educacional.
TERRITÓRIOS INDÍGENAS E CAPITALISMO
Authors: Rodrigues Marco Antonio , Cavararo Rodrigues Andrea Lucia , Aguilera Urquiza Antonio Hilario
Published: February 2022

O presente artigo é fruto do projeto de pesquisa em andamento, intitulado ‘A Dinâmica Migratória dos Povos Tradicionais Fronteiriços no Estado do Mato Grosso do Sul e os Reflexos da Mensagem de Veto nº 163/2017”, o qual se insere em projeto mais amplo (OGUATA GUASU E TERRITÓRIO: Uma análise antropológica da mobilidade guarani nas fronteiras de Mato Grosso do Sul), financiado pelo CNPq. O artigo busca analisar a abolição da Lei Glass-Steagall e a concepção neoliberal, articulando esse estudo com as políticas estatais de demarcação de terras indígenas na região fronteiriça do Estado do Mato Grosso do Sul, chegando-se à conclusão de que o Estado, enquanto vinculado ao capital, permanecerá distante de suas reais finalidades no tocante às populações tradicionais e à efetivação de direitos, conforme se reflete na mensagem de veto estudada. Através da pesquisa bibliográfica, jurisprudencial e histórica o artigo buscará chegar ao resultado esperado.