bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancement of thermoelectric power factor in Si-doped Mg3Sb2 compoundfor thermoelectric converting applications
Authors:   Faculty of Materials Science and Engineering, Phenikaa University, Mac Trung Kien ,   Phenikaa Research and Technology Institute (PRATI), Pham Kim Ngoc ,   Faculty of Materials Science and Engineering, Phenikaa University,   Phenikaa Research and Technology Institute (PRATI), Das Raja ,   Faculty of Materials Science and Engineering, Phenikaa University,   Phenikaa Research and Technology Institute (PRATI), Nguyen Huu Tuan ,   Faculty of Materials Science and Engineering, Phenikaa University,   Phenikaa Research and Technology Institute (PRATI), Tran Dang Thanh ,   Institute of Materials Science, VAST,   Graduate University of Science and Technology, VAST, Pham Bach Thang ,   Center for Innovative Materials and Architectures, Vietnam National University, Ho Chi Minh city, Duong Anh Tuan ,   Faculty of Materials Science and Engineering, Phenikaa University,   Phenikaa Research and Technology Institute (PRATI)
Published: November 2022

Mg3Sb2 is a narrow band gap semiconductor with electrical conductivity and thermoelectric properties dependent on structure and doping elements. In this study, to improve the thermoelectric properties of Mg3Sb2, the authors doped Si at different ratios (x=0.05, 0.1, 0.15, 0.25, and 0.3) into Sb sites as the formula Mg3Sb2-xSix to improve the electrical conductivity of doping samples while maintaining a high value of the Seebeck coefficient. The results exhibited that Mg3Sb2 and Mg3Sb2-xSixcompounds prepared by solid phase reaction method (high energy grinding combined with hot pressing and sintering) showed hexagonal structure. The electrical conductivity of the Si-doped samples increased significantly compared to the undoped Mg3Sb2 sample, while the Seebeck coefficient slightly decreased in the low doping contents samples and highest increase in the Mg3Sb1.75Si0.25 sample. The power factor of all doping samples increased compared to undoped samples. The power factor values at 673K of Mg3Sb1.9Si0.1, Mg3Sb1.75Si0.25, and Mg3Sb1.7Si0.3 increased around 1.7 times compared to the Mg3Sb2
Generating a construct harboring the rpb1 promoter for enhancing recombinant protein expression in the medicinal mushroom Cordyceps militaris
Authors:   Faculty of Biology, University of Science, Vietnam National University, Hanoi, Tran Van Tuan ,   National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi, Nguyen Minh Thu ,   Faculty of Biology, University of Science, Vietnam National University, Hanoi, Bui Thi Khanh Linh ,   Faculty of Biology, University of Science, Vietnam National University, Hanoi, Pham Thi Thu Huong ,   Faculty of Biology, University of Science, Vietnam National University, Hanoi,   National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi, Pham Thanh Hien ,   National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi, Le Thi Hong Nhung ,   Faculty of Biology, University of Science, Vietnam National University, Hanoi,   National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi, Hoang Thi My Nhung ,   Faculty of Biology, University of Science, Vietnam National University, Hanoi,   National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi
Published: November 2022

Cordyceps militaris is a valuable medicinal mushroom that contains numerous bioactive ingredients such as cordycepin, adenosine, pentostatin, polysaccharides, and carotenoids. However, the contents of these substances in wild-type strains of C. militaris are relatively low. Recently, the genome of C. militaris has been fully sequenced, and genes involved in the biosynthesis of beneficial constituents have been identified. Therefore, research on enhancing the biosynthesis of the bioactive compounds in this fungus by recombinant DNA technology has advantages. In the present study, the authors have successfully generated a binary vector with a T-DNA region carrying a construct regulated by the native rpb1 promoter that can enhance gene expression in C. militaris. The T-DNA structure from the binary vector was then transferred into the C. militaris genome by Agrobacterium tumefaciens-mediated transformation. Analysis of some fungal transformants by PCR using the specific primer pairs indicated that the T-DNA structure was successfully integrated into the fungal genome. Observation of the transformants under fluorescence microscopy confirmed the overexpression of the DsRed fluorescent protein under the regulation of the rpb1promoter. The binary vector carrying the rpb1 promoter constructed in this study can be employed to promote the expression of target genes in the medicinal mushroom C. militaris.
Synthesis of copper (II) citrate and evaluation ofits in vitro antifungaland antibacterial activities, and the suitability of using this chemicalas a plant protection agent
Authors:   Vinh University, Le The Tam , Nguyen Hoa Du ,   Vinh University, Bui Thu Trang ,   Faculty of Chemical Technology, Hanoi University of Industry, Hoang Duc Nghia ,   Faculty of Chemical Technology, Hanoi University of Industry,   Institute for Tropical Technology, Vietnam Academy of Science and Technology, Ho Dinh Quang ,   Vinh University, Tran Quang De ,   College of Natural Sciences, Can Tho University, Le Dang Quang ,   Institute for Tropical Technology, Vietnam Academy of Science and Technology,   Graduate University of Science and Technology, Vietnam Academy of Science and Technology
Published: November 2022

In this paper, copper (II) citrate Cu3(C6H5O7)2 was successfully synthesised in an aqueous solution. The factors for the synthesis process such as temperature and molar ratio of the reactants were investigated. The structural, properties and composition characteristics of the elements were investigated and evaluated by X-ray diffraction pattern (XRD), Fourier-transform infrared spectroscopy (FTIR), energy-dispersive X-ray spectroscopy (EDX), and UV-Vis spectroscopy. The yield of the copper (II) citrate in the reaction was 82.46% at the molar ratio of the CuSO4/C6H5Na3O7 of 1.5/1 at 70oC. The in vitro results showed that copper (II) citrate at a concentration of 1,000 ppm inhibits the mycelial growth of Sclerotium rolfsii and Fusarium oxysporumwith control values ranging from 19 to 53% after 2 days of incubation. Besides, it strongly suppressed the plant bacterial pathogens Xanthomonas axonopodis (bacterial strain causing citrus canker), Ralstonia solanacearum(bacterial wilt of tomato), and Clavibacter michiganensis subsp. michiganensis (cause of bacterial wilt and canker of tomato). These results suggested that copper (II) citrate can be used as a promising fungicide/bactericide to control fungal and bacterial diseases on citrus and tomato plants.
Ecological risks of some heavy metals in sediment samples collected from downstream of the Red river
Authors:   Hanoi University of Natural Resources and Environment, Trinh Thi Tham , Le Thi Trinh ,   Hanoi University of Natural Resources and Environment, Trinh Thi Thuy ,   Hanoi University of Natural Resources and Environment
Published: November 2022

This study aimed to assess the accumulation of some heavy metals such as Cu, Pb, Cd, and Cr in the sediments collected from downstream of the Red river from the south of Hanoi city to Nam Truc district, Nam Dinh province. Besides, the geological accumulation index (Igeo) and the potential ecological risk index were calculated to understand the impact of heavy metal content in the sediments on the ecosystem. The results showed that the concentration of several metals (Cu, Pb, Cd, Cr) in 20 sediment samples was lower than the permitted values specified in Technical Regulations on sediment quality (QCVN 43:2017/BTNMT). However, according to the Canadian guidelines, the concentrations of metals in 50% of samples had a low level of effect. The potential ecological risk index of metals ranges from 1.8 to 11.6, revealing that the study area has a low-level metal risk. This data can clarify the area’s potential risk level and provide the scientific basis for recommending measures to control and reduce sources of metal pollution into the aquatic environment.
Improving the viability of Lactobacillus plantarum VAL6using environmental-stress adaptation
Authors:   An Giang University, Vietnam National University, Ho Chi Minh City, Nguyen Huu Thanh , Nguyen Thanh Dung ,   Nguyen Trung Truc High School, Kien Giang, Nguyen Phu Tho ,   An Giang University, Vietnam National University, Ho Chi Minh City, Nguyen Thi To Uyen ,   Science and Technology Application Center, Can Tho city Department of Science and Technology, Bui Nhi Binh ,   Science and Technology Application Center, Can Tho city Department of Science and Technology, Pham Thuy Vy ,   Science and Technology Application Center, Can Tho city Department of Science and Technology, Nguyen Hoang Tinh ,   Science and Technology Application Center, Can Tho city Department of Science and Technology, Dang Chi Thien ,   Science and Technology Application Center, Can Tho city Department of Science and Technology, Nguyen Thi Bich Nhu ,   Science and Technology Application Center, Can Tho city Department of Science and Technology
Published: November 2022

To demonstrate the adaptation of lactic acid bacteria to environmental stresses can improve cell viability during freeze-drying, the Lactobacillus plantarum VAL6 strain was cultured under different stress conditions, including temperature, pH, and increase in CO2 concentration. The results of densitometry analysis showed that the strain was able to survive in harsh environmental conditions such as at pH 2.5, the temperature at 47oC, and in anaerobic conditions created by CO2. In particular, the CO2 intensification culture could stimulate an increase in the density of L. plantarum VAL6, reaching 9.4 compared to 9 LogCFU/ml under normal culture conditions. After cells were adapted to environmental stress at pH 3.5, the highest survival rate after freeze-drying of L. plantarum VAL6 was 28% (2,500 times higher than that of the control). The results showed the potential to use environmental stresses to increase the survival rate of starter lactic acid bacteria strains for food applications.
CONTROLLING AS A TOOL TO ENSURE THE ECONOMIC SECURITY OF AN ORGANIZATION
Authors: Tkacheva Maria , Utochkina Lyudmila
Published: November 2022

Introduction. In modern conditions, economic entities are creating and implementing effective mechanisms for carrying out their activities in a competitive market. Particularly acute issues are ensuring the competitiveness of products, the business image of the organization, adjusting plans with minimal losses of any resources. Objectives. Comprehensive study of the essence of controlling as a tool for ensuring the economic security of an organization. Development of an approach for determining its main tasks and functions based on a risk-based approach, as well as the development of provisions for the organizational and methodological support of control-ling in the system of economic entity functioning in the face of increasing destructive influence of external threats. Methods. The theoretical basis was such general scientific methods of cog-nition as analysis, synthesis, a systematic approach to the processes and phenomena studied in the article, detailing. To interpret the results obtained during the study, a logical approach, comparison, summaries, groupings and other methods were used. Results. The systematization of existing approaches to the disclosure of the essence of controlling was carried out, a descrip-tion of the object of study based on an integrated approach was given, which made it possible to determine its main tasks, functions, and impact on the system of ensuring economic security that has developed in the organization. An algorithm for the interaction of controlling with oth-er tools for ensuring the economic security of the organization was presented, which made it possible to determine its place in the management system of an economic entity. Conclusions. The concept of using controlling as a tool to ensure the economic security of an organization involves a close relationship between the structural elements of the organization, focusing on the main aspects of its functioning, namely the planning and budgeting system, the strategic management system, management accounting with a detailed analysis of cost factors, infor-mation flows, monitoring and analysis of the results of financial and economic activities of an economic entity. A feature of the proposed model for the implementation of controlling func-tions is to ensure the solution of individual tasks of controlling by each block of the scheme, which will allow rationally distributing functional powers between departments to achieve the greatest efficiency.
ANALYSIS OF ECONOMIC SECURITY AND POTENTIAL OF THE VOLGOGRAD REGION
Authors: Bogdanova Margarita
Published: November 2022

Introduction. Economic security is the foundation on which the successful functioning of the state as a subject of world economic relations is based, capable of ensuring the vital activity of its own population and the prospects for its existence in the future. It is a complex and multifaceted structure. Being a part of the national security system, it simultaneously forms the basis for the formation of all the elements included in its structure. The purpose of the article is to analyze the economic potential and assess the economic security of the Volgograd region. Methodology. The instrumental and methodological apparatus of the research is based on the use of general scientific and special methods, including abstract-logical, monographic, computational-constructive, graphical, methods of multidimensional statistical analysis, content analysis. Results. The geopolitical, tourist and natural potentials of the region are analyzed, the demographic situation and the gross regional product are assessed, the state of the budgetary and financial sphere is assessed. The analysis of the level of economic security of the Volgograd region and its potential is carried out. Conclusions. The article presents, as a result of assessing the level of economic security of the Volgograd region, its strengths and weaknesses, as well as the projected measures for further development of strengths and elimination of weaknesses.
SARS-CoV-2 infection outcomes associated with the Delta variant: A prospective cohort study
Authors: Gallant Maxime , Rioux-Perreault Christine , Lemaire-Paquette Samuel , Piché Alain
Published: November 2022

Background:

It is well established that fully vaccinated (≥2 doses) individuals may develop COVID-19. However, little is known about the specific prevalence of post-COVID-19 conditions associated with the Delta variant or the effect of vaccination on post-acute outcomes of COVID-19. In addition, how Delta variant infection severity compares in fully vaccinated individuals versus in those unvaccinated is unknown.

Methods:

This prospective single-centre observational cohort study assessed adults with SARS-CoV-2 proven infection from August 1 to November 1, 2021. Study participants were enrolled in the Biobanque Québécoise de la COVID-19. Data on demographics, comorbidities, and severity of COVID-19 were collected. Simple and multiple logistic regressions were used to identify risk factors for post-COVID-19 conditions.

Results:

Among the 395 individuals who were interviewed by phone, 138 (39.4%) agreed to participate. Of the 138 participants, 62.8% were Delta-associated breakthrough infections that occurred in fully vaccinated individuals and 37.1% in unvaccinated individuals. The majority (93.5%) had a history of mild COVID-19 illness. The prevalence of Delta-variant-associated post-COVID-19 conditions was similar in both vaccinated (61.4%) and unvaccinated (51.4%) groups ( p = 0.347). The number of symptoms during acute infection was an independent risk factor for post-COVID-19 conditions.

Conclusions:

This study is the first to describe the incidence of Delta-associated post-COVID-19 condition. In this study, COVID-19 vaccination was not associated with decreased post-COVID-19 conditions in patients with breakthrough Delta infection. These findings have important implications for provincial services planning and underscore the need to develop alternative strategies to prevent post-COVID-19 conditions.
Theoretical and methodological principles of tax regulation of the development of territorial communities in Ukraine
Authors: Klymenko Andrii
Published: November 2022

It is emphasized in the article that in the process of forming tax regulation of socio-economic development of territories in Ukraine is a key place belongs to a clear system of scientific and methodological support. It is proposed to choose a systems approach as the methodological basis of the study, which consists in using the fundamental methodological concept of the system as a single abstract reflection of the objects of reality; identification of key determinants, properties, features and trends of the system; interpretation of the researched problem as a conceptual system. It is established that the study of tax regulation of socio-economic development of territorial communities is an element of the general system of state management of national economy, closely related to the processes of transformation of administrative structure, financial decentralization and improvement of socio-economic indicators of society in Ukraine at the municipal level. The peculiarities, principles and approaches of scientific knowledge inherent in the system method are revealed. The key directions of research of tax regulation of social and economic development of territorial communities in Ukraine are formed. Using the system method, a conceptual model of tax regulation of socio-economic development of territorial communities in Ukraine as a set of interrelated elements of influence on the economic system at the level of a separate territory, including: purpose, objects and subjects of taxation, principles and process of taxation as a financial instrument for socio-economic development of territories. It is proposed to consider tax regulation taking into account: national priorities of socio-economic development of the country; resource opportunities, industry-production, geographical-territorial, socio-demographic and other features of territorial communities; coherence of interests of state and local budgets; ensuring financial self-sufficiency of local self-government; certainty of the direction of development of the tax system, starting from the level of territorial communities.
Foreign investments and their investment in the economy of Ukraine with the help of the fund market
Authors: Kryvenko Yuliia
Published: November 2022

Subject of research is foreign investments. The purpose of this article is a study of the nature and peculiarities of attracting foreign investments into the Ukrainian economy through the stock market. Methods which were used in course of research: method of system-structural analysis and synthesis, method of comparative analysis, generalization, general scientific, special methods of scientific knowledge and other methods of research. Study results. The role of attracting investments into the country's economy is characterized. The essence, importance and necessity of intensifying the investment function and the participation of households in economic relations with regard to the purchase of various financial assets in the stock market are investigated. Negative phenomena in investment activity are identified and the main ways of improving the investment climate of Ukraine are identified. Application of results. The results of the study can be used in the activities of the Ministry of Finance of Ukraine, the Verkhovna Rada of Ukraine, the National Securities and Stock Market Commission, as well as in higher education institutions in teaching economic disciplines. Conclusions. Reinvigorating economic, including investment and innovation, and improving social conditions on this basis is only possible through decisive, comprehensive and consistent market reforms that will free up entrepreneurial initiative, create a competitive environment and provide the economy with incentives for effective development.
Theoretical principles of digitalization of the treasury of Ukraine
Authors: Mykytyuk Igor
Published: November 2022

Relevance of the research topic. The development and mastering of modern computer systems and their software open up wide opportunities for the treasury service to increase the effectiveness and efficiency of the functioning of the treasury system of servicing budgets at all levels, improving the quality of financial services provided by the treasury bodies, which determines the relevance of the topic of this study. Analysis of recent research and publications. Studies of issues related to the introduction of the latest information technologies, information support of the Treasury's needs with modern technologies were covered in the scientific literature by such scientists as V. M. Vdovin, G. A. Tytorenko, M. A. Abrosymova, T. B. Kublikova, E. I. Kurganska, Yu. O. Golynskyi, L. M. Lutsiv, O. O. Skoryk, O. M. Sevasteeva, L. Gordienko and others. However, despite existing scientific research, the issues of digitalization of the State Treasury Service of Ukraine do not lose their relevance and require further research. Highlighting unexplored parts of the general problem. Taking into account the constant transformation processes in the Treasury bodies, there are practically no scientific works devoted to the implementation of digitalization in the Treasury bodies. Setting the task, the goal of the research. The tasks of the study are to reveal the essence of the digitalization of the Treasury, tasks, goals and principles of digitalization. The purpose of the article is to study the theoretical foundations of the digitalization of Treasury bodies. Method or methodology of research. The article uses a set of scientific research methods: system approach, analysis, synthesis. Presentation of the main material. The essence and necessity of digitalization of activities of Treasury bodies is revealed. The tasks, principles and purpose of digitalization are determined. The analysis is carried out and the theoretical foundations of digitalization are defined. Field of application of results. The results of the study can be used in the process of forming a strategy for the digitalization of Treasury bodies. Conclusions from this study and prospects for further research in this direction. The validity of the theoretical foundations of the digitalization of the Treasury, with the determination of its purpose, tasks and principles, is a valid condition for the development of a strategy for the digitalization of the Treasury's bodies. In view of the transformational processes of the development of the treasury service of budget funds, the issues of new and improvement of the existing tools of standardization and optimization of advanced information technologies, aimed at the modernization and unification of treasury procedures, are significant and require further research.
The theoretical basis of accounting payments to employees of healthcare institutions
Authors: Perchuk Oksana , Lyashenko Mykyta , Mala Julia
Published: November 2022

The subject of research: theoretical provisions and current practice of accounting for employee benefits. The purpose of the study is to generalize and substantiate the theoretical aspects of accounting for payments to employees of health care institutions. Method or methodology for conducting research. The methodological basis of the research is the general theoretical methods of scientific knowledge, the main approaches and provisions of the accounting of payments to employees, which are highlighted in the works of domestic and foreign scientists. The following methods were used to fulfill the tasks: dialectical method of cognition - for the analysis of legislative and normative documents and scientific works of scientists related to the issue of personnel payments, in particular in the medical field; analysis and synthesis - when researching and summarizing foreign and domestic experience of the theoretical foundations of accounting for employee benefits; abstract-logical – for theoretical generalizations and formulation of conclusions. The field of application of results. The results of the study can be used in the practical activities of health care institutions to improve the effectiveness of personnel policy. The results of research and conclusions. On the basis of the conducted research, the essence of the concept of "payments to employees" as an object of accounting was revealed, and their structure was determined, taking into account the peculiarities of social guarantees in the field of remuneration of employees of health care institutions.
Іmprovement of accounting and calculations for the payment of labor in agricultural enterprises based on a systematic approach and organizational innovations
Authors: Skrypnyk Svitlana , Koval Svitlana , Shepel Inesa
Published: November 2022

The subject of the study is the theoretical and practical aspects of improving accounting and payroll calculations. The purpose of the article is to identify problems and justify directions for improving the accounting of wages and salaries in agricultural enterprises on the basis of a systematic approach and the implementation of organizational innovations. The methodological basis of the article was the theoretical and methodological provisions of accounting and taxation; normative-legislative acts and fundamental works of scientists on this issue. The following methods were used: historical, abstract-logical, dialectical, monographic, system-structural analysis and synthesis, statistical-economic, double-entry, accounting accounts, balance sheet, accounting and financial reporting. Results of the article. Based on the principles of the system approach, the difference between remuneration as a process and wages as a result of labor, as well as their identical features, was revealed. The latter allow to develop and identify the forms of labor payment, their content and advantages and possibilities of application. The trend of increasing individualization of labor and its payment on the basis of contracts has been determined. The importance of accounting for labor remuneration for increasing its productivity and ensuring the efficiency of agricultural enterprises is substantiated. Field of application of results. The received practical recommendations and developments can be implemented in the economic and accounting activities of enterprises; divisions of tax services; educational and research process of economic and accounting faculties of higher education institutions. Conclusions. A systematic approach to labor and its accounting made it possible to determine the difference between wages and wages; characterize tariff and other forms of their implementation as organizational innovations; justify accounting tasks. Completion of payroll accounting tasks has a positive effect on the image, functioning efficiency and competitiveness of the development of agrarian enterprises through the stimulation of compliance with the rules of internal labor regulations, the conscientious performance of their duties by employees, and a favorable moral climate in the team. This ensures the coherence of the accounting work from the moment of filling out the primary document to the display of information about accrued and paid wages in the reporting. It is the correct organization of remuneration, observance of fair proportions, ratios, accounting of wage amounts with conditions and results of work that serve as a primary factor in stimulating labor productivity, employee interest in improving results and quality of work.
Environmental taxation and a reflection of its main elements in the accounting system
Authors: Sliusar Svitlana
Published: November 2022

The subject of research is the procedure for taxation and reflection of environmental tax in the accounting system. The purpose of the article is to disclose a methodological approach to environmental taxation in Ukraine, which will make it possible to develop proposals for improving the information base formed by the accounting system and its further use in order to form various types of reporting, as well as planning actions to reduce the amount of pollution by business entities. The methodological basis of the study is the general scientific and special methods of scientific knowledge, applied at the empirical and theoretical levels of research: comparative, analytical, selective, dialectical, systematic approach, induction and deduction, generalization. Results of work. The article carried out studies of the current state of taxation in the context of components of environmental taxes, analyzed the volume of such taxes in the budget by types of environmental pollution. National, regional and local administrative levels of influence have been identified that allow the implementation of environmental plans and measures in the legal field. Taking into account the current requirements of users of accounting information, the documentary reflection of the economic activity of the calculation of environmental tax obligations has been improved. A complex of analytical accounting system for settlement operations with the environmental tax budget was developed and its practical application is presented. Field of application of results in the activities of economic entities in certain sectors of the economy. Conclusions. The proposed procedure for reflecting transactions under accrued budgetary obligations is the result of compliance with environmental tax requirements. Environmental accounting, in turn, is the basis for obtaining this information on costs, analyzing and monitoring rational environmental activities. Therefore, the main objective of environmental accounting is to develop expense items to account for general operating expenses (or to form a separate sub-account to account for environmental expenses under the items) and accounting for 92 Administrative expenses. At the same time, аpplication of accounting standart 16 "Expenses" facilitates the provision of a list of items of expenses related to their accounting.
Socio-economic contribution of cooperative publishing house "hart" to the development of the publishing industry of Ukraine
Authors: Kostyk Yevhenii
Published: November 2022

The subject of research is: formation; development; structure of governing bodies; operational and economic organization of the material base and consumer interests of buyers of book products of the cooperative publishing house "Hart". The purpose of the scientific article is to reveal and show the socio-economic contribution of the cooperative publishing house "Hart" to the development of the publishing industry of Ukraine based on the sources. Research methods. All components of the research are based on the main principles - scientificity, historicism, objectivity, systematicity, development, priority of concrete truth, pluralism, as well as methods of learning socio-economic processes of social development – analysis, synthesis, problem-chronological, comparative-analytical, archeographic, retrospective, statistical, systematic and complex approach. Work methodology. In the process of researching the specified issues, the main provisions were taken as a basis: the history of Ukraine, economic history and the history of economic thought, the history of the publishing industry, the work of domestic and foreign scientists and practitioners in the specified field. Work results. In the context of the mentioned problems, we investigated the socio-economic contribution of the cooperative publishing house "Hart" to the development of the publishing industry of Ukraine. Field of application of results. The results of this study can be applied in the field of studying the problems of economic history and the history of economic thought, the history of the publishing industry. Conclusions. In the context of our research, we found out that the socio-economic contribution of cooperative publishing houses, in particular "Hart", to the development of the publishing industry of Ukraine, is quite large, since these publishing houses, with their entrepreneurial activity, stimulated the publishing process, thanks to them, the works of famous figures saw the light of day of Ukrainian culture, well-known historians, publicists, whose heritage remains understudied. It should be noted that in Ukraine at the current stage of development of the market economy system, where various forms of ownership dominate, the national publishing industry is in an extremely difficult situation. The search for an effective model for the development of national book publishing is still ongoing, so why not turn to our own historical experience.
Evaluation of the effectiveness of the activities of customs authorities in the framework of the regulation of foreign trade and ensuring the economic security of Russia
Authors: Tabolskaia Vaktoriia Valerevna
Published: November 2022

Customs authorities occupy an important place in the state regulation of foreign trade activities. The article discusses the activities of customs authorities in terms of effi-ciency and effectiveness. The study was carried out through the study of statistical da-ta. The fulfillment of the main criteria for the effectiveness of the activities of the cus-toms authorities has a positive effect on the state of foreign trade and the foreign trade balance, and hence the economic development of Russia.
Development and validation of headteachers' leadership behavior questionnaire (HLBQ)
Authors: Nyla Ramzan  , Khurram Azmat Farooq Ahmad , Nighat Ahsan
Published: November 2022

The leadership behavior of the headteachers is associated with institutional worth. This study intended to develop and validate a headteachers’ leadership behavior questionnaire (HLBQ) to measure the leadership behavior of headteachers. The questionnaire encompassed two sub-dimensions viz: people-oriented leadership behavior and task-oriented leadership behavior as per Blake and Mouton’s Managerial Grid. After a rigorous literature review followed by focus group discussions, the preliminary draft of the tool encompassed forty-three (43) items on the five (5) points Likert Scale. Based on the content and face validity, the items with CVR values less than 0.42 were dropped. The revised questionnaire was pilot tested on three hundred and ten (310) public secondary school teachers employed in the school education department. The data were processed through Smart PLS version 4, which provided the questionnaire’s validity, reliability, and model fit. After deleting the unfit items, the questionnaire was further reduced to thirty-one (31) items. AVE values of the items related to people-oriented leadership behavior were 0.658 > 0.5, and for task-oriented were 0.686 > 0.5. Fornell-Lacker criterion value (0.828) was more than the correlations with other latent constructs, i.e., 0.811 and 0.831. The Heterotrait-Monotrait ratio (HTMT) value was 0.859 < 0.9, which is acceptable. Cronbach alpha for people-oriented leadership behavior was 0.967 > 0.7, and task-oriented leadership behavior was 0.658 > 0.7. Similarly, the composite reliability (CR) values for people-oriented leadership behavior were 0.970 > 0.7, and task-oriented leadership behavior was 0.963 > 0.7. Thus, the headteachers’ leadership behavior questionnaire (HTLB) was internally consistent, valid, and reliable. The findings of the entire study supported using the headteachers’ leadership behavior questionnaire (HLBQ) to explore and measure the leadership behavior of the headteachers.
The neurodevelopmental outcomes of children with encephalocele: a series of 102 patients
Authors: Kankam Samuel Berchi , Tavallaii Amin , Mohammadi Esmaeil , Nejat Amirhosein , Habibi Zohreh , Nejat Farideh
Published: November 2022

OBJECTIVE

The overall prognosis of encephalocele (EC) is not well described. However, the presence of some risk factors may result in neurodevelopmental delay (NDD) and negatively affect the prognosis of affected patients. The goal of this study was to evaluate neurodevelopmental outcome, as well as the impact of a number of factors on the outcome in patients with ECs.

METHODS

This was an observational, retrospective study including 102 children with EC who were followed at the pediatric neurosurgery department of a tertiary medical center between the years 2010 and 2021. The authors evaluated NDD status according to the Centers for Disease Control and Prevention classification via clinical evaluation and parent interviews in the outpatient setting.

RESULTS

There were 52 boys and 50 girls. The median age at the time of surgery was 4 months (range 1 day–7.5 years). Seventy-one patients (69.6%) had posterior ECs, whereas 31 (30.4%) had anterior ECs. Forty-three (42.2%) of the ECs contained neural tissue. Of the 102 patients, 33 (32.4%) had ventriculomegaly. In terms of NDD, 14 (14.9%) had mild/moderate delay, whereas 17 patients (18.1%) had severe NDD. On univariate analysis, posterior location, size of sac, presence of neural tissue, ventriculomegaly, symptomatic hydrocephalus, and postoperative infection were correlated with NDD. On a multivariate logistic regression model, only neural tissue presence had a statistically significant association with NDD (OR 7.04, 95% CI 1.33–37.2, p = 0.022). Although not statistically significant, children with ventriculomegaly were 2.6 times as likely to have NDD (95% CI 0.59–11.19, p = 0.362).

CONCLUSIONS

This is a single-center study with a large sample size in which the neurodevelopmental status of patients with EC was assessed, and the authors tried to find the risk factors of NDD in these patients. The results showed that the presence of neural tissue within the EC sac was the only risk factor that had independent statistically significant association with NDD.
Current state and future direction of quality improvement in pediatric neurosurgery: a survey of pediatric neurosurgeons
Authors: Pendola Gabriella , Koutsouras George W. , Piatt Joseph , Kaufman Bruce A. , Sandoval-Garcia Carolina , Drapeau Annie I.
Published: November 2022

OBJECTIVE

Quality improvement (QI) is a methodology used to implement sustainable, meaningful change to improve patient outcomes. Given the complex pathologies observed in pediatric neurosurgery, QI projects could potentially improve patient care. Overall, there is a need to characterize the degree of QI opportunities, training, and initiatives within the field of pediatric neurosurgery. Herein the authors aimed to define the current QI landscape in pediatric neurosurgery.

METHODS

A cross-sectional survey was sent to all members of the American Association of Neurological Surgeons/Congress of Neurological Surgeons Joint Section on Pediatric Neurological Surgery via email. The responses were anonymized. Questions addressed several relatable QI topics including 1) training and participation in QI; 2) QI infrastructure; 3) QI program incentives; and 4) general opinions on the National Surgical Quality Improvement Program (NSQIP) database, various QI topics, and QI productivity.

RESULTS

Responses were received from 129 participants (20% response rate). Most respondents practiced in an academic setting (59.8%) and at a free-standing pediatric hospital (65.4%). Participation in QI projects was high (81.7%), but only 23.8% of respondents had formal QI training. Only 36.5% of respondents had institutional requirements for QI work; the majority of those were only required to participate as a project team member. Nearly half of the respondents did not receive incentives or institutional support for QI. The majority agreed ("strongly" and "somewhat") that a QI course would be beneficial (75.5%), that QI projects should be considered for publication in neurosurgery journals (88.1%), and that there is a need for national quality metrics (81.4%). Over 88% have an interest in seeing QI project presentations at the annual Pediatric Joint Section meeting. Only 26.3% believed that the NSQIP was a useful QI guide. Respondents suggested further study of the following QI topics: overall rates of infection and their prevention, hydrocephalus, standardized treatment algorithms for common disorders, team communication, pediatric neurosurgery–specific database, access to care, and interprofessional education.

CONCLUSIONS

Areas of opportunity include specialty-specific QI education, tactics for obtaining support to build the QI infrastructure, increased visibility of QI work within pediatric neurosurgery, and a review of available registries to provide readily available data relevant to this specialty.
Effective Reading Instruction in ESP: Practical Approaches to Improving Vocational Students’ Content-Area Reading Comprehension
Authors: TAMRIN Tamrin
Published: November 2022

Effective reading instruction in Vocational Higher Education (henceforth VHE) has been criticized as ineffective, as demonstrated by poor reading test results, indicating a deficient students’ reading performance. This article examines and gains insight into the reasons why things occur as they do by discussing the following four topics: (1) describing the context in which reading instruction occurs and why this instructional effort does not work as expected; (2) describing the nature of content area reading; (3) unpacking things that could potentially encourage students’ interests and increase their reading involvement, thereby making their reading more effective; and (4) proposing a set of pedagogical principles that could potentially improve the students optimal reading and comprehension
Numerical Investigation on Three Local-Adaptive k-Point Multiquadric Neural Networks
Authors: Paewpolsong Pichapop , Chanthawara Krittidej , Dungkratoke Narongdech , Kaennakham Sayan
Published: November 2022

Under the architecture of a neural network, this work proposes and applies three multiquadric radial basis function (MQ-RBF) interpolation schemes; The Common Local Radial Basis Function Scheme (CLRBF), The Iterative Local Radial Basis Function Scheme (ILRBF), and The Radius Local Radial Basis Function Scheme (RLRBF). The schemes are designed to perform locally to overcome drawbacks normally encountered when using a global one. The famous Franke function in two dimensions is numerically tackled. It is revealed in this work that all three local methods outperform the traditional MQ interpolation in terms of both CPU-time and condition number, while the accuracy is overall acceptable, particularly when the number of nodes increases. This finding indicates their potential for dealing with bigger datasets and more complex problems.
Retrospective Bayesian Evidence of Null Effect in Two Decades of Alzheimer’s Disease Clinical Trials
Authors: Costa Tommaso , Manuello Jordi , Cauda Franco , Liloia Donato
Published: November 2022

Despite intense research on Alzheimer’s disease, no validated treatment able to reverse symptomatology or stop disease progression exists. A recent systematic review by Kim and colleagues evaluated possible reasons behind the failure of the majority of the clinical trials. As the focus was on methodological factors, no statistical trends were examined in detail. Here, we aim to complete this picture leveraging on Bayesian analysis. In particular, we tested whether the failure of those clinical trials was essentially due to insufficient statistical power or to lack of a true effect. The strong Bayes’ Factor obtained supported the latter hypothesis.
Impact of Computerized Cognitive Training on Default Mode Network Connectivity in Subjects at Risk for Alzheimer’s Disease: A 78-week Randomized Controlled Trial
Authors: Petrella Jeffrey R. , Michael Andrew M. , Qian Min , Nwosu Adaora , Sneed Joel , Goldberg Terry E. , Devanand Davangere P. , Doraiswamy P. Murali
Published: November 2022

Background: Mild cognitive impairment (MCI) represents a high risk group for Alzheimer’s disease (AD). Computerized Cognitive Games Training (CCT) is an investigational strategy to improve targeted functions in MCI through the modulation of cognitive networks. Objective: The goal of this study was to examine the effect of CCT versus a non-targeted active brain exercise on functional cognitive networks. Methods: 107 patients with MCI were randomized to CCT or web-based crossword puzzles. Resting-state functional MRI (fMRI) was obtained at baseline and 18 months to evaluate differences in fMRI measured within- and between-network functional connectivity (FC) of the default mode network (DMN) and other large-scale brain networks: the executive control, salience, and sensorimotor networks. Results: There were no differences between crosswords and games in the primary outcome, within-network DMN FC across all subjects. However, secondary analyses suggest differential effects on between-network connectivity involving the DMN and SLN, and within-network connectivity of the DMN in subjects with late MCI. Paradoxically, in both cases, there was a decrease in FC for games and an increase for the crosswords control (p < 0.05), accompanied by lesser cognitive decline in the crosswords group. Conclusion: Results do not support a differential impact on within-network DMN FC between games and crossword puzzle interventions. However, crossword puzzles might result in cognitively beneficial remodeling between the DMN and other networks in more severely impaired MCI subjects, parallel to the observed clinical benefits.
Huntingtin Overexpression Does Not Alter Overall Survival in Murine Cancer Models
Authors: Chan Laura Lynn , Hill Austin , Lu Ge , Van Raamsdonk Jeremy , Gascoyne Randy , Hayden Michael R. , Leavitt Blair R.
Published: November 2022

A reduced incidence of various forms of cancer has been reported in Huntington’s disease patients and may be due to pro-apoptotic effects of mutant huntingtin. We tested this hypothesis by assessing the effects of huntingtin protein overexpression on survival in two murine cancer models. We generated YAC HD mice containing human huntingtin transgenes with various CAG tract lengths (YAC18, YAC72, YAC128) on either an Msh2 or p53 null background which have increased cancer incidence. In both mouse models of cancer, the overexpression of either mutant or wild-type huntingtin had no significant effect on overall survival. These results do not support the hypothesis that mutant huntingtin expression is protective against cancer.
A review of rumor detection techniques in social networks
Authors: Liu Yao , Shen Hao , Shi Lei
Published: November 2022

Social networks have accelerated the speed and scope of information dissemination. However, the lack of regulation and freedom of speech on social platforms has resulted in the widespread dissemination of the unverified message. Therefore, rapid and effective detection of social network rumors is essential to purify the network environment and maintain public security. Currently, the defects of rumor detection technology are that the detection time is too long and the timeliness is poor. In addition, the differences based on specific regions or specific fields will lead to deviations in the training dataset. In this paper, firstly, the definition of rumor is described, and the current problems and detection process of rumor detection are described; Secondly, introduce different data acquisition methods and analyze their advantages and disadvantages; Thirdly, according to the development of rumor detection technology, the existing rumor detection methods of artificial, machine learning and deep learning are analyzed and compared; Finally, the challenges of social network rumor detection technology are summarized.