bluuebunny/crossref_metadata_2025 huggingface dataset:
ผลของชนิดอิเล็กโทรไลต์และสารเติมแต่งต่อขั้วสังกะสีในแบตเตอรี่สังกะสี-ไอออนโดยใช้การหาลักษณะเฉพาะแบบอิน-ซิทู
Authors:   , ภุมมารี พรนภา
Published: June 2024

โลหะสังกะสีมักถูกนำมาใช้เป็นวัสดุในแบตเตอรี่สังกะสี-ไอออน เนื่องจากราคาถูก และเป็นมิตรต่อสิ่งแวดล้อม แต่ยังมีข้อจำกัดจากการเกิดเดนไดรต์ การกัดกร่อน และการเกิดปฏิกิริยาข้างเคียงที่ผันกลับไม่ได้ส่งผลให้แบตเตอรี่มีเสื่อมสภาพ ในปัจจุบันเทคนิคอิน-ซิทูได้รับความสนใจอย่างมากในการศึกษา เพราะสามารถศึกษาได้โดยไม่ต้องแยกส่วนแบตเตอรี่ และวิเคราะห์การเปลี่ยนแปลงที่เกิดขึ้น ณ เวลาจริงได้ โดยในงานวิจัยนี้ใช้การวิเคราะห์แบบอิ-ซิทูกล้องจุลทรรศน์แบบใช้แสงเพื่ออธิบายสัณฐานวิทยาที่ขั้วสังกะสีโดยเฉพาะอย่างยิ่งโครงสร้างเดนไดรต์ขที่บริเวนส่วนต่อระหว่างสารละลายอิเล็กโทรไลต์กับขั้วสังกะสีในเซลล์สมมาตรของขั้วสังกะสี (Zn/Zn) ในระหว่างที่เกิดการละลาย/พอกพูนของสังกะสี ตัวแปรที่ได้ทำการศึกษาคือ ชนิดของเกลือในสารละลายอิเล็กโทรไลต์ ชนิดของสารเติมแต่ง และความเข้มข้นของสารเติมแต่ง ชนิดของเกลือได้แก่ ZnSO4 และ Zn(CF3SO3 โดยกำหนดให้ความเข้มข้นของเกลืออยู่ที่ 1 โมลาร์ในน้ำซึ่งเป็นตัวทำละลายของสารละลายอิเล็กโทรไลต์และสารเติมแต่งคือ MnSO4 SiO2 และ PEG นำมาใช้แค่ในระบบสารละลายอิเล็กโทรไลต์ ZnSO4 ความเข้มข้น 1 โมลาร์ ความหนาแน่นกระแสที่ใช้คือ  0.5 1.0 2.0 และ 4.0 มิลลิแอแปร์ต่อตารางเซนติเมตร และความจุ 2 มิลลิแอแปร์-ชั่วโมงต่อตารางเซนติเมตร และจำนวนรอบของการอัดและจ่ายประจุคือ 10 25 50 100 และ 200 รอบ โดยที่ความหนาแน่นกระแสสูง 4.0 มิลลิแอแปร์ต่อตารางเซนติเมตร จะเกิดเดนไดรต์อย่างรุนแรงจนสามารถทะลุแผ่นกั้นส่งผลให้เกิดการลัดวงจรอ้างอิงจากผลทางเคมีไฟฟ้า การถ่ายภาพจากกล้องจุลทรรศน์แบบใช้แสง และการถ่ายภาพด้วยรังสีเอกซ์เรย์ซินโครตรอน จากผลวิจัยพบว่าการเติมซิลิกาปริมาณ 0.5 % โดยมวลต่อปริมตารช่วยยับยั้งการเกิดเดนไดรต์ได้ ยิ่งไปกว่านั้นยังลดการเกิดการกัดกร่อนและการเกิดปฏิกิริยาข้างเคียงที่ผันกลับไม่ได้บนผิวขั้วสังกะสีได้อีกด้วย สอดคล้องกับผลทางเคมีไฟฟ้าที่มีเสถียรภาพสูงและจากภาพถ่ายกล้องจุลทรรศน์ที่พื้นผิวของขั้วสังกะสีนั้นไม่เปลี่ยนแปลงจากเดิม และจากผลของรามานสเปกโตสโกปีพบว่าพื้นผิวของขั้วสังกะสีนั้นไม่มี ZnO, Zn(OH)2 และ Zn4SO4(OH)6
สารทำเครื่องหมายสำหรับน้ำมันปิโตรเลียมที่วิเคราะห์โดยการวัดสีและวัดการเรืองแสงจากคาร์ดานอลที่เติมไฮโดรเจน
Authors:   , รัตนมุณี พิมพ์ใจ
Published: June 2024

ในงานวิจัยนี้ผู้วิจัยประสบความสำเร็จในการเตรียมสีย้อมขึ้นมาใหม่สี่ชนิด ได้แก่ AzoHC, diAzoHC, AFHC และ NPHC เพื่อใช้เป็นสารทำเครื่องหมายสำหรับน้ำมันปิโตรเลียม โดยสีย้อมทั้งหมดมีไฮโดรจีเนเตดคาร์ดานอล (HC) เป็นหมู่แทนที่ ซึ่งได้มาจากของเสียในอุตสาหกรรมอาหารทำให้ราคาไม่แพง โดยสามารถแบ่งสีย้อมได้เป็นสองประเภท คือ สีย้อมที่วิเคราะห์โดยการวัดสี และสีย้อมที่วิเคราะห์โดยวัดการเรืองแสง โดยสีย้อมที่วิเคราะห์โดยการวัดสี ได้แก่ AzoHC และ diAzoHC ประกอบด้วยหมู่ไดเอโซหนึ่งและสองหมู่ ตามลำดับ และมีหมู่ไฮโดรเจนคาร์ดานอลที่ไม่ชอบน้ำ สำหรับการเตรียม AzoHC เตรียมจาก 4-ไนโตรอะนิลีนที่มีจำหน่ายทั่วไป (NTAL, ผลิตภัณฑ์ 62 เปอร์เซนต์) ในขณะที่ diAzoHC ได้จากออร์โธ-อะมิโนโทลูอีน (AMT, ผลิตภัณฑ์ 60 เปอร์เซนต์) ผ่านไดอะโซไทเซชันด้วยไฮโดรจีเนเตดคาร์ดานอล ในขณะที่สีย้อมแบบฟลูออโรจีนิกอีกสองชนิด ได้แก่ ฟลูออเรสซีน AFHC และแนพทาลีไมด์ NPHC ถูกเตรียมจากพทาลิกแอนไฮไดรด์ (PA) และ 4-โบรโม-เอ็น-ฟีนิล-1,8-แนพทาลีไมด์ (BrNP) ซึ่งราคาไม่แพง ตามลำดับ โดยให้ผลผลิตที่ดี และโครงสร้างของสีย้อมที่เตรียมทั้งหมดได้รับการยืนยันเอกลักษณ์ด้วย NMR spectroscopy, IR spectroscopy และ Mass spectrometry โดยสีย้อม AzoHC, diAzoHC และ AFHC มีความสามารถในการละลายในน้ำมันดีเซลได้ดีที่ความเข้มข้นมากกว่า 15,625 ppm ในขณะที่สีย้อม NPHC ไม่สามารถละลายในตัวอย่างน้ำมัน ดังนั้นจึงไม่สามารถใช้เป็นสารทำเครื่องหมายสำหรับน้ำมันปิโตรเลียมได้ น้ำมันดีเซลที่ทำเครื่องหมายด้วย AzoHC หรือ diAzoHC ที่ความเข้มข้น 1-40 ppm ให้การเปลี่ยนแปลงของสีที่ชัดเจน ในขณะที่สีย้อม AFHC ส่งผลให้การเปลี่ยนแปลงสัญญาณการเรืองแสงสูงขึ้นเมื่อเติมสารทำให้เกิดสีที่เหมาะสมการเติมโพแทสเซียมไฮดรอกไซด์ในไอโซโพรพานอล (IPA, 1 M) เป็นสารทำให้เกิดสีในน้ำมันดีเซลที่มี AzoHC หรือ diAzoHC ทำให้เกิดเป็นสารละลายเนื้อเดียวกันพร้อมทั้งเกิดการเปลี่ยนสีที่ชัดเจนจากสีเหลืองเป็นสีแดงหรือสีแดงอมส้ม ตามลำดับ ผลการศึกษาเหล่านี้สอดคล้องกับการเพิ่มขึ้นของค่าสูงสุดในการดูดกลืนแสงที่ 528 นาโนเมตรเมื่อตรวจสอบด้วยเครื่องยูวี-วิสิเบิล สเปกโทรโฟโตมิเตอร์ ผู้วิจัยพบว่าลิมิตของการตรวจวัด (LOD) ของน้ำมันดีเซลที่มีสีย้อม AzoHC และ diAzoHC อยู่ที่ 1.27 และ 2.71 ppm ตามลำดับ สีย้อมทั้งสองเข้ากันได้ดีและสามารถใช้เป็นสารทำเครื่องหมายสำหรับน้ำมันปิโตรเลียมกับน้ำมันที่จำหน่ายเชิงพาณิชย์ที่แตกต่างกัน 8 ชนิด ได้สำเร็จ เมื่อตรวจสอบความคงตัวของสีย้อมทั้งสองชนิดพบว่าสามารถเก็บไว้ได้นานกว่า 60 วันในสภาวะปกติ ในกรณีของสีย้อม AFHC พบว่าสารละลายโพแทสเซียมไฮดรอกไซด์ในเอ็น-บิวทานอล (BuOH) เป็นสารทำให้เกิดสีที่เหมาะสมที่สุด เมื่อใช้ AFHC กับน้ำมันดีเซลพรีเมียมและน้ำมันก๊าดที่ความเข้มข้นระหว่าง 1-40 ppm ไม่พบสีที่สังเกตได้ทั้งก่อนและหลังการเติมสารทำให้เกิดสี อย่างไรก็ตาม น้ำมันดีเซลพรีเมียมและน้ำมันก๊าดที่มีสีย้อมดังกล่าวแสดงค่าสัญญาณเรืองแสงเพิ่มขึ้นที่ 525 นาโนเมตร เมื่อตรวจสอบโดยฟลูออโรมิเตอร์ ค่าลิมิตของการตรวจวัดของน้ำมันดีเซลพรีเมียมและน้ำมันก๊าดที่มีสีย้อม AFHC อยู่ที่ 1.36 และ 0.75 ppm ตามลำดับ
Mixture sutoregressive models for Thai stock market data
Authors:   , Suthichayapipat Apicha
Published: June 2024

The autoregressive (AR) model is one of the most widely used time series forecasting models. The standard AR model was established using the normal distribution, which is violated in some datasets, notably financial data. Therefore, alternative distributions are proposed in the literature, such as the concept of mixture distributions. This concept is also applied to time series modeling in the family of mixture autoregressive models that combine different autoregressive components. Specifically, we consider both the univariate mixture autoregressive model and the multivariate mixture autoregressive model based on the normal and t distributions. In this study, we construct the EM algorithm to estimate parameters and investigate the performance of this method compared with the MLE. The analysis focuses on top stocks from two different sectors in the market, namely energy and utility and electronic components, with each sector comprising three stocks. The fitted models are compared with the family of mixture autoregressive models by using AIC, HQIC, BIC, and MSE of predictions. The results indicate that the EM algorithm is preferred for Thai stock market data.
Dynamic nearest neighbor classifier using mass-ratio-variance outlier factors for class imbalance problem
Authors:   , Fuangfoo Patcharasiri
Published: June 2024

The objective of classifcation is to assign a class to a given data instance. One
well-recognized classifer is the k-NN model, where the class of an instance is determined
by considering the majority class among its k nearest neighbors. However, k-NN’s performance weakens in imbalanced datasets. To address this, adjusting k for each instance based on factors like its position
relative to clusters or isolation, and integrating density-based scores from a parameterfree Mass-ratio-variance Outlier Factor (MOF) into the k-NN process, helps determine
suitable nearest neighbors.
Our research focuses on the development of a dynamic nearest neighbor classifer
tailored specifcally to address class imbalance problems. Experimental results on ten
real-world datasets show our classifer accurately forecasts outcomes, aligning closely with
traditional k-NN with the best parameter k.
The use of diatoms (Amphora sp.) As immunostimulant in pacific white shrimp (Litopenaeus vannamei) diet
Authors:   , Thongdet Ekthida
Published: June 2024

Amphora sp. is one of the interesting microalgae due to its rapid growth, high lipid content, ranging from 40-60% of dry biomass, suitability as live food for commercial aquatic animal larvae such as shrimp and abalone. The objective of this study is to evaluate the potential of Amphora sp. isolated from four different locations in the Gulf of Thailand: Sichang Island (ASC), Samae Sarn Island (ASS), Pranburi (APB), and Laem Yai (ALY) as immunostimulant in Pacific white shrimp (Litopenaeus vannamei) diet. Four Amphora sp. isolations were cultured and compared productivity. The results showed that ASC and ALY had higher productivity, lipid content and polyunsaturated fatty acid composition compared to the other 2 strains. These ASC and ALY were chosen for optimum culture condition experiment, varied with 3 light intensities and 2 medium concentrations. The results showed that ALY cultured with medium light intensity with F/20 medium can produce higher biomass, saturated fatty acids, and important unsaturated fatty acids than the other culture condition. Shrimp fed with 15% of this Amphora sp. for 6 weeks demonstrated the higher survival rate from challenge test than 3 weeks. In addition, the expression of LvALF gene that response for Anti-lipopolysaccharide factors in hepatopancrease have been found. This finding indicated that adding 15% Amphora sp. in shrimp diet may enhance immunity of shrimp infected with V. parahaemolyticus. However further study in immune parameters such as PO and SOD must be included to clarify the mechanism of shrimp immune system.
Kinetic mechanism of dimethylsulfone monooxygenase and its immobilized magnetic nanoparticles
Authors:   , Mangkalee Montisa
Published: June 2024

The dimethyl sulfone monooxygenase system is a two-component flavoprotein catalyzing the monooxygenation of dimethyl sulfone (DMSO2) by oxidative cleavage producing methanesulfinate and formaldehyde. The reductase component (DMSR) is a flavoprotein with FMN as a cofactor catalyzing flavin reduction using NADH. The oxygenase (DMSMO) uses reduced flavin from the reductase and oxygen for substrate monooxygenation. DMSMO can bind to FMN and FMNH– with a Kd of 17.4 ± 0.9 µM and 4.08 ± 0.8 mM, respectively.  The binding of FMN to DMSMO is required prior to binding DMSO2. Substituting reduced DMSR with FMNH– demonstrated the same oxidation kinetics, indicating that FMNH- from DMSR was transferred to DMSMO. The oxidation of FMNH–:DMSMO, with and without DMSO2 did not generate any flavin adducts for monooxygenation. Therefore, H2O2 is likely to be the reactive agent to attack the substrate. The H2O2 assay results demonstrated production of H2O2 from the oxidation of FMNH–:DMSMO, whereas H2O2 was not detected in the presence of DMSO2, confirming H2O2 utilization. The rate constant for methanesulfinate formation determined from rapid-quenched flow and the rate constant for flavin oxidation were similar, indicating that H2O2 rapidly reacts with dimethyl sulfone. Both enzymes have been co-immobilized onto Ni-NTA functionalized magnetic nanoparticles (CoFe2O4@SiO2–Ni/NTA) to improve enzyme stability in different environments and enable the enzymes to be recovered for reuse.
Information security awareness lesson using gamification
Authors:   , Rintanalert Thanawat
Published: June 2024

In the landscape of education, where engagement and retention are pivotal, gamification emerges as a dynamic strategy. This research delves into the realm of gamification, a process that infuses the captivating allure of videogame mechanics into educational contexts. Embarking on an experimental journey, this study orchestrates an intricate interplay between two distinct groups of undergraduate students – Group A, the "Gamified Group," and Group B, the "Traditional Group."

Within this dynamic framework, Group A immerses itself in the immersive realm of educational videogames to grasp the nuances of information security awareness. In parallel, Group B embraces a more traditional approach, delving into the same subject matter through video presentations. Both groups subsequently engage in rigorous quizzes to evaluate their comprehension. The results unfold a compelling narrative: the Gamified Group exhibits heightened enthusiasm and active participation, unveiling a landscape where learning transcends the boundaries of monotony.

As the data crystallizes, the test scores echo a resounding resonance – the Gamified Group's average score eclipses that of the Traditional Group. Deeper insights gleaned from student interviews validate the potential of videogames as potent tools of education. A harmonious convergence of traditional pedagogies and gamified dynamics emerges, fostering heightened class participation and enhancing memorization capacities.

This research transcends its experimental confines, illuminating a pathway towards the evolution of education videogames. By unraveling the potential synergies between gaming mechanics and educational objectives, it paves the way for more efficacious, engaging, and accessible learning experiences. In the wake of this exploration, the horizon of education stands enriched, poised to embrace the multifaceted potential of gamification as a conduit to elevate pedagogical landscapes.
Vegetation dynamics and sea-level changes in the upper gulf of Thailand
Authors:   , Sukaudom Dissaya
Published: June 2024

Climate change plays a role in sea level fluctuation, either transgression or regression leads to coastline evolution. Samut Sakhon province is located on the coast in the upper Gulf of Thailand therefore past sea-level studies in this area can contribute information to a better understanding of sediment dynamics and assess future coastline development. The study site provides sedimentary sequences consisting of 9 sediment units from 25.5-7.2 m. DBS, results of LOI, Ti/Ca, and Zr/Rb ratio, grain size, and pollen analysis were interpreted together with radiocarbon dating to reconstruct past environments in the study site. The past environment in Samut Sakhon site can divided into two parts in the late Pleistocene (26.5-22.7 cal ka BP), Samut Sakhon was temporal exposure during dry conditions, and in the mid/late Holocene (5.4-1.1 cal ka BP), mangrove forests grew due to sea level transgression at 5.4-4.4 cal ka BP before being transferred into the back-mangrove forest at 4.4-4.2 cal ka BP and wetland during sea level regression at 4.2-2.3 cal ka BP, respectively. Samut Sakhon site was likely to be a brackish area thereafter at 2.3-1.1 cal ka BP. To improve the level accuracy and decrease data discrepancies, autonomous level monitoring, and differential global positioning systems should be used in combination with future research.
Chitosan blending with water-soluble polymers as dissolving microneedles for controlled drug release
Authors:   , Saleh Fuad
Published: June 2024

Chitosan has gained significant interest due to its ability to film-forming, biodegradability, and biocompatibility, making it suitable for topical and transdermal drug delivery such as fabricating microneedles. In this study, chitosan microneedles were prepared by incorporating polyvinylpyrrolidone (PVP) and polyvinyl alcohol (PVA) in three different ratios (1:1, 2:1, and 3:1 chitosan: polymers) to control drug release. The microneedles were fabricated using a molding method, their mechanical properties were tested using the universal testing machine (UTM), and their skin penetration ability was tested using pig skin (ex vivo). The results indicated that the microneedles exhibited sufficient strength to penetrate the outer layer of the porcine skin effectively. The study included incorporating two drugs: curcumin as a model of hydrophobic drugs, and butterfly pea extract as a model of hydrophilic drugs. Chitosan blended with PVP demonstrated the ability to finely tune the release profiles with approximately 90% of hydrophilic and 60% of hydrophobic loaded drugs being released from the microneedles over four days. In contrast, chitosan blended with PVA did not exhibit a significant difference from the blank microneedles, releasing only 49% of the loaded drugs over two days. These findings suggest that chitosan microneedles incorporating PVP are a promising candidate for controlled transdermal drug delivery, offering versatility in releasing both hydrophobic and hydrophilic compounds.
ثورات الربيع العربي وتأثيرها على التيار السلفي في اليمن
Authors: الشرفي أ.د.محمد شرف , دغار د.أحمد محمد هادي
Published: June 2024

يتناول البحث تأثير ثورات الربيع العربي على التيار السلفي في اليمن، ويركز على التحولات الفكرية والسياسية التي طرأت على هذا التيار بعد الثورات. يوضح البحث أن الجماعات السلفية في اليمن، مثل جمعية الحكمة وجمعية الإحسان، تأثرت بشكل كبير بهذه الثورات، مما دفعها إلى تبني مواقف سياسية جديدة والانتقال من العمل الدعوي البحت إلى الانخراط في الحياة السياسية. كما يسلط الضوء على الانقسامات الداخلية والخلافات التي نشبت بين قيادات السلفية التقليدية والجديدة نتيجة لهذه التحولات. يستخدم البحث المنهج الوصفي التحليلي لدراسة الظاهرة، مستنداً إلى مصادر تاريخية وتحليلات معاصرة. يهدف البحث إلى تقديم رؤية شاملة لفهم ديناميكيات التيار السلفي في اليمن وتأثير الثورات العربية عليه، مع التركيز على إمكانية قبول التيار السلفي للمفاهيم الديمقراطية والدولة المدنية في المستقبل.
Desarrollo de habilidades del siglo XXI a través de la educación STEM
Authors: Chiliquinga Masaquiza Raymy Rafael , Rodríguez Arce Karen Lisbeth , Luje Pozo David Inti , Pucha Gualoto Oscar Iván
Published: June 2024

En la era contemporánea, el avance tecnológico y científico ha transformado significativamente los ámbitos laborales y educativos, haciendo indispensables las habilidades del siglo XXI como el pensamiento crítico, la creatividad, la colaboración y la resolución de problemas. La educación STEM (Ciencia, Tecnología, Ingeniería y Matemáticas) emerge como una respuesta esencial para estos desafíos, enfocándose no solo en conocimientos técnicos, sino también en competencias transversales que preparan a los estudiantes para resolver problemas del mundo real con creatividad e innovación. Este enfoque promueve un aprendizaje activo y experiencial, integrando metodologías como el Aprendizaje Basado en Problemas y Proyectos. Desde su implementación global en la década de los noventa, STEM ha demostrado ser eficaz en el desarrollo de habilidades críticas para el siglo XXI, preparando a los estudiantes para adaptarse a las demandas del mercado laboral contemporáneo y enfrentar los desafíos futuros con eficacia y resiliencia.
Growth Performance, Carcass Characteristics and Histological Indices of White Fulani (Bunaji) Bull Yearling Calves Fed Graded Levels of Urea and Molasses Ensiled Rice Straw Supplemented with Maize Offal and Cowpea Husk
Authors: Adamu B. , Surayya A. , Dapellum A.U. , Furo Ya`u Adamu , Muhammed Usman Abba
Published: June 2024

The study was carried out at Duware farm along Yola-Fufore Road Adamawa state. ix yearling white Fulani (Bunaji) bull calves weighed 80kg-100kg were fed graded levels of urea and molasses ensiled rice straw supplemented with maize offal and cowpea husk to investigate the growth performance, carcass characteristics and histological indices. The treatments diets consist of graded levels of urea and molasses ensiled rice straw supplemented with maize offal for T1, graded levels of urea and molasses ensiled rice straw supplemented with cowpea husk in T2, and graded levels of urea and molasses ensiled rice straw only in T3 (control group). The feeds were offered at 8; 00 am in the morning and 6:00 pm in the evening, remnants were weight before fresh feeds were offered, mineral lick and water was provided ad-libitum, and animals were weight weekly to determine their growth performance. Two weeks adaptation period was carried out, the experiment last for three months including the adaptation period, statistical package for data analysis was completely randomize design (CRD) and the values were subjected to analysis of variance (ANOVA) means were separated using least significant difference (LSD).
Association between cerebral small vessel disease and plasma levels of LDL cholesterol and homocysteine: Implications for cognitive function
Authors: Cheng Yan , Li Lichao , Lv Yafei , Zhang Long , Chen Wenhua , Xu Gongda
Published: June 2024

Background: Investigate the correlation between low-density lipoprotein (LDL) cholesterol, homocysteine and cognitive function in patients with cerebral small vessel disease (CSVD). Methods: 240 patients with CSVD confirmed by head MRI in the Department of Neurology from January 2020 to December 2023 were retrospectively included in the study. All the patients had complete blood biochemical examination, and their cognitive function was evaluated by Montreal Cognitive Assessment Scale (MoCA), and after correcting for the factor of years of education, the patients were divided into a group of normal cognition (MoCA 26, 70 patients) and a group of cognitive function (MoCA 26, 70 patients) according to the scores. After correcting for the factor of years of education, the patients were divided into the normal cognitive function group (70 cases with MoCA 26) and the cognitive dysfunction group (170 cases with MoCA <26) according to their scores. The general information of the two groups and the patients' cognitive function characteristics, including visuospatial and executive ability, naming, attention and calculation, language, abstraction, delayed memory, and orientation, were compared, and the independent influences on the occurrence of cognitive dysfunction in patients with CSVD were analyzed by two-category multifactorial logistic regression. Results: Compared with the group with normal cognitive function, the cognitive dysfunction group had lower years of education and higher homocysteine, and the differences were statistically significant (P < 0.05). Compared with the group with normal cognitive functioning, the cognitive dysfunction group had lower MoCA total scores, lower visuospatial and executive ability, naming, attention and calculation, language, abstraction, delayed memory, and orientation scores, and the differences were statistically significant (P < 0.05). Two-category multifactorial logistic regression analysis showed that low-density lipoprotein cholesterol (OR=2.756, 95% CI: 0.673-0.938, P=0.012) and homocysteine (OR=1.859, 95% CI: 1.024-1.324, P=0.016) were the independent factors influencing cognitive dysfunction in CSVD patients. The lower the risk of cognitive impairment in CSVD patients, the higher the plasma LDL cholesterol and homocysteine levels, the higher the risk of cognitive impairment in CSVD patients. Conclusions: Plasma LDL cholesterol and homocysteine levels are associated with and may be predictors of cognitive dysfunction in patients with CSVD.
Use of antibiotics and antivirals in the treatment of COVID-19 patients in the COVID outpatient clinic of Primary Healthcare Center Golubac
Authors: Trifunović Boban
Published: June 2024

Introduction: There were 13 protocols for the COVID-19 infection treatment in Serbia. All protocols emphasize the importance of not giving antibiotics routinely, especially in patients who were treated at the primary healthcare level. Use of antibiotics was widely spread in the treatment of COVID-19 patients, all around the world. Objective. We aimed at examining the incidence, type, and combination of used antibiotics and antivirals in COVID-19 patients. Method: Observational retrospective cross-sectional study on the prescription of antibiotics and antivirals in patients who were treated in the COVID clinic of the Golubac Primary Healthcare Center in the period from 7/17/2020. until 10/31/2022. The data were obtained from the electronic health records of the participants. The sample consisted of 2709 respondents. The variables we used were sex and age. We used the statistical package SPSS17 for data processing. For statistical methods, we used descriptive statistics frequency (%) and, the X2 test. Results: The research included 2,709 patients. In total, 1590 people were prescribed antibiotics. Concerning the total number of patients, examined in the COVID clinic, this represents 58.7%. The highest percentage of patients who were prescribed an antibiotic was in the period November 2020 - May 2021. Depending on the study period, cephalosporin and azithromycin are the most frequently prescribed antibiotics (70-89% of the total number of prescribed antibiotics). The most commonly prescribed antibiotic combination is a cephalosporin-fluoroquinolone. Conclusion. The use of antibiotics in the treatment of COVID-19 patients was higher than recommended in the protocols and guidelines.
Diabetic ketoacidosis in pregnancy
Authors: Novaković Ivana , Todorović Jovana , Dugalić Stefan , Macura Maja , Milinčić Miloš , Gojnić Miroslava
Published: June 2024

Diabetic ketoacidosis (DKA) is one of the most serious and life-threatening complications of diabetes mellitus (DM), especially when it occurs during pregnancy, with a prevalence ranging from 0.5% to 3%. Pregnancy is considered a susceptible environment for the development of this type of metabolic imbalance due to its inherent physiological changes. Unspecific symptoms (vomiting, diarrhea, abdominal pain, etc.), especially in pregnant women, and the fact that ketoacidosis can develop even with normal glucose values (defined as euglycemic ketoacidosis), often lead to a delayed diagnosis. Evidence suggests that timely diagnosis and appropriate management of ketoacidosis are crucial in preventing adverse outcomes for both the mother and the fetus. Fetal outcomes are often dichotomous, resulting in either fetal demise (miscarriage/stillbirth) with a prevalence of 10% to 35%, or the birth of a healthy baby, with possible complications primarily related to diabetes mellitus itself. Additionally, case reports of ketoacidosis developing even in non-diabetic women due to other diseases (such as acute pancreatitis, appendicitis), as well as in those with gestational diabetes mellitus (GDM), further emphasize the importance of considering this condition in everyday clinical practice. The aim of this paper is to further elucidate the causes and course of this complication, as well as the outcomes for both mother and fetus, to contribute to a better overall understanding.
Pengaruh Faktor Ekonomi Makro Terhadap Kinerja Saham Di Pasar Modal Global
Authors: Ficeroy Recky
Published: June 2024

Penelitian ini menyelidiki pengaruh faktor ekonomi makro, seperti inflasi, suku bunga, dan kurs rupiah terhadap kinerja saham di pasar modal global. Dengan menggunakan analisis statistik yang cermat, penelitian ini mengidentifikasi hubungan dan dampak variabel-variabel ekonomi tersebut terhadap pergerakan harga saham di berbagai bursa saham di seluruh dunia. Temuan penelitian ini memberikan wawasan berharga bagi investor dan praktisi pasar modal dalam mengantisipasi dan mengelola risiko serta mengambil keputusan investasi yang lebih tepat di tengah dinamika perekonomian global.
Recursos educativos digitales para mejorar el aprendizaje en matemáticas
Authors: Asqui Lema Beto Orlando
Published: June 2024

En la actualidad, el aprendizaje de las matemáticas resulta fundamental en diversas áreas del conocimiento, pues fomenta el pensamiento lógico, la resolución de problemas y la toma de decisiones informadas. Las TICs desempeñan un papel crucial en este proceso, al proporcionar herramientas interactivas, simulaciones y recursos multimedia que posibilitan que el aprendizaje sea de fácil acceso, dinámico y atractivo para los estudiantes. Esta investigación analiza los recursos educativos digitales más usados en el aprendizaje matemático, mediante una revisión bibliográfica, con el propósito de mejorar las prácticas educativas y promover habilidades matemáticas. Se utilizó una metodología documental cualitativa, enfocada en recopilar y analizar herramientas, plataformas y recursos digitales para el aprendizaje matemático. Los resultados resaltan que la integración de estrategias didácticas innovadoras y herramientas digitales mejora significativamente el aprendizaje matemático, y promueve la comprensión profunda y el compromiso de los estudiantes. Estas herramientas digitales diversifican el aprendizaje de las matemáticas al ofrecer funciones como modelado, resolución de problemas, gestión educativa y colaboración en línea. GeoGebra y Symbolab son útiles para comprender conceptos complejos y resolver problemas, mientras que Khan Academy brinda cursos en línea con recursos interactivos. En tanto, Google Classroom y Jamboard optimizan la gestión y colaboración en el aula. Kahoot y MathGameTime introducen elementos lúdicos, mientras que Descartes, Logic.ly y Scratch ofrecen herramientas para simulaciones, lógica y programación visual, respectivamente.
How Hopelessness in University Students is Associated with Intolerance of Uncertainty and Other Factors: A Cross- Sectional Study
Authors: Engin Esra , Güler Cansu , Yaşar Sevilcan
Published: June 2024

Objective: This study aims to examine the relationship between hopelessness, intolerance of uncertainty, and other factors among university students.

Material and Methods: This study has a descriptive cross-sectional design. The sample of the study consists of 371 students continuing their education at a university. The data of the study were collected online using the Intolerance of Uncertainty Scale, Beck Hopelessness Scale, and a 10-item general characteristics form. Student's t-test, ANOVA, Pearson correlation coefficient, and hierarchical regression analysis were used for the analysis of data with normally distributed variables.

Results: The mean age of the participants is 22.03±1.72. The mean score of intolerance of uncertainty is 39.38±10.36, and the mean score of the Beck Hopelessness Scale is 7.07±5.52. It has been observed that low income, receiving education in the field of health sciences, experiencing low efficiency in online education, and intolerance of uncertainty scores of university students predict levels of hopelessness (p
Bipolar Mood Disorder in Older Age Individuals
Authors: Kaya Tuğba , Turgut Celaleddin
Published: June 2024

Since geriatric individuals are a rapidly growing segment of the population, the number of patients with bipolar mood disorder is increasing gradually. Treatment options become more difficult as a result of increasing organic diseases and comorbid psychiatric disorders with increasing age, and the treatment of geriatric bipolar mood disorder patients can be more complex than that of younger patients, considering the sensitivity to side effects due to pharmacological treatments. The aim of this study is to present the prevalence of bipolar mood disorder in the older age group, the symptoms affecting them, and the current status of comorbid disorders by collecting information from the studies in the related literature. It is of critical importance examining the neurodegeneration of bipolar mood disorder in more detail in future studies. With more interventional studies, it will be possible to support organic diseases and psychiatric comorbidities that occur with advancing age. Local studies on the treatment protocols will help to reduce the burden created on patients.
Nörolojik Hastalıklarda Yoga Kullanımının Etkileri
Authors: Dolu Sevim , Çırak Kübra , Canpolat Muhammed , Taşan Nazan , Parlar Kılıç Serap
Published: June 2024

Yoga, fiziksel egzersizleri, nefes alma tekniklerini, meditasyonu ve sağlıklı bir yaşam tarzını birleştiren ve Hint felsefesine dayanan eski bir yöntemdir. Yoga, sistemlerimizi dengelemek için zihni (meditasyon) ve bedeni (egzersizler) kullanan manevi bir uygulamadır. Zihnin duyguları ve bedeni etkileme yeteneklerini araştırır. Bu nedenle Ulusal Tamamlayıcı Alternatif Tıp Merkezi (The National Center for Complementary Alternative Medicine) yogayı zihin-beden tıbbı olarak sınıflandırır. Zihin-beden terapileri beyin, zihin, beden ve davranış arasındaki ilişkilere ve bunların sağlık ve hastalık üzerindeki etkilerine odaklanır. Yoga uygulaması da sağlık ve esenliği iyileştirmek için bireyin fiziksel, zihinsel ve ruhsal bileşenlerini bütünleştirir. Bu nedenle yoga bir bilim olduğu kadar ayrıca sağlıklı yaşam sanatıdır. Sağlığın geliştirilmesi, hastalıkların önlenmesi ve nörolojik bozukluklar için olası bir tedavi yöntemi olarak yaygın bir şekilde kullanılmaktadır. Multiple skleroz, parkinson, demans, epilepsi, alzheimer hastalığı, baş ağrıları ve inme gibi çeşitli nörolojik hastalıklardaki etkilerini araştıran çalışmalarda yoga pratiğinin hastalık semptomları, denge, güç, esneklik, bilişsel durum, depresyon, anksiyete ve yaşam kalitesi üzerinde etkili olduğu bildirilmiştir. Yoganın nörolojik hastalıklardaki sağlık üzerine olumlu etkileri göz önünde bulundurulduğunda; hastalar için makul derecede güvenli, uygun maliyetli, uygulanabilir ve umut verici bir yöntem olduğu söylenebilir. Hastaların eğitiminde en önemli rolü oynayan sağlık profesyonelleri olarak hemşirelerin, nörolojik hastalıklardaki semptomları yönetebilecek ve kontrol edebilecek mevcut tamamlayıcı ve bütünleştirici yöntemler hakkında bilgilendirilmeleri çok önemlidir. Ayrıca hemşireler, hastalara özellikle ileri düzey yoga uygulamaları yapılırken hastaların istenmeyen etkilerden kaçınmalarını sağlamak için gereken bilgilendirmeyi ve özeni göstermeleri gereklidir. Bu derlemenin amacı nörolojik hastalıklarda kullanılan yoga uygulamasının sonuçlarının incelenmesidir.
Genç Bireylerde Soğuk Uygulamanın Eklem Pozisyon Hissi, Deri Sıcaklığı ve Kas Kuvveti Üzerine Etkisi
Authors: Yıldız Zeynep , Işıntaş Meltem
Published: June 2024

Amaç: Çalışmamızın amacı soğuk uygulamanın omuzda eklem pozisyon hissi ve maksimum istemli izometrik kas kuvveti üzerine etkisini araştırmaktı.

Gereç ve Yöntem: Kontrolsüz deneysel çalışmaya 18-24 yaş aralığındaki 44 genç birey dahil edildi. Soğuk uygulama için, 2 adet soğuk jel paket omuz bölgesine 20 dakika uygulandı. Deri sıcaklığı Mastercool infrared termometre ile, eklem pozisyon hissi Cybex Humac Norm İzokinetik Test ve Egzersiz Sistemi cihazı ile değerlendirildi. Cihaz ile 12 sn aralıklı 3 set şeklinde eksternal ve internal rotatörlerin kas kuvveti ölçüldü ve ortalama tork alındı. Soğuk uygulama öncesi ve sonrası değerler istatistiksel olarak karşılaştırıldı.

Bulgular: Soğuk uygulama öncesi ve sonrası, deri sıcaklığı (dominant; t=46,32; p
Antiphospholipid antibodies and antiphospholipid syndrome
Authors: Hansen Rasmus Søgaard , Larsen Julie Brogaard , Vinholt Pernille Just , Voss Anne , Abildgaard Anders
Published: June 2024

Individuals with antiphospholipid syndrome (APS) have antibodies directed against phospholipid-binding proteins (aPL). The condition is most associated with an increased risk of thromboembolism and obstetric complications. The 2023 classification criteria for APS include six clinical domains (venous thromboembolism, arterial thrombosis, microvascular events, obstetric events, cardiac valve, thrombocytopaenia) and two laboratory domains (lupus anticoagulant, and anti-cardiolipin or anti–β2-glycoprotein-I antibodies). Diagnosis and treatment of APS are specialist tasks and are summarised in this review.
Estudo ambiental em minibacias hidrográficas do semiárido brasileiro utilizando a metodologia de Rocha e Kurtz (2007)
Authors: SILVA DANILO duarte costa e
Published: June 2024

No contexto atual, a deterioração das regiões semiáridas tem recebido considerável atenção da mídia e da comunidade científica. O Brasil, com seu semiárido, amplamente reconhecido como o mais desafiador do mundo, enfrenta não apenas pressões naturais, mas também as consequências de políticas públicas equivocadas ao longo dos anos. Esse cenário de deterioração em constante crescimento evidencia a necessidade urgente de abordagens metodológicas que possam combater os problemas locais. A presente pesquisa se baseia em um modelo metodológico de análise ambiental de bacias hidrográficas [17], aplicado com sucesso em várias minibacias hidrográficas do semiárido do Rio Grande do Norte - Brasil. Os resultados revelaram níveis de degradação acima do limite aceitável, destacando a urgência de intervenção por parte do poder público, especialmente nas minibacias hidrográficas mais afetadas.
The Effect of Digital Transformation on Vietnam's Regulatory Framework
Authors: Kim Hieu Bui
Published: June 2024

The context in which businesses operate and interact with citizens has been significantly altered as a result of Vietnam's accelerated digital transformation. This research investigates the effects of digital transformation on Vietnam's regulatory framework, with an emphasis on the opportunities and challenges that result from the country's digital expansion. A strong legal framework is acknowledged as a critical component in the realization of the objectives of the National digital transformation program by 2025, with a focus on 2030, which involves the establishment of three pillars: digital governance, digital economy, and digital society. The article provides a comprehensive analysis of the legal framework that facilitates Vietnam's digital transformation and suggests several suggestions for advancing the digital transformation process in the future. The results suggest that the digital transformation has generated a critical need for regulatory reform, particularly in the realms of data protection, e-commerce, and digital payments. The study emphasizes the necessity of a unified legal framework, enhanced enforcement mechanisms, and increased public awareness. Nevertheless, it also recognizes opportunities for economic development and innovation, such as the potential for digital regulations to stimulate employment creation and investment. The study concludes by delineating a roadmap for the future of Vietnam's regulatory framework, underscoring the significance of stakeholder engagement, transparency, and adaptability. Vietnam can establish a regulatory framework that promotes economic growth and individual rights by confronting the obstacles and capitalizing on the opportunities that digital transformation presents.
Camuflaje (Jonathan Perel, 2022). Cartografiar el pasado, cartografiar el presente
Authors: Lusnich Ana Laura
Published: June 2024

A cuarenta años de la recuperación de la democracia, las representaciones cinematográficas y audiovisuales en torno al pasado dictatorial no cesan. Ficciones, documentales, animaciones, narraciones transmedia y otros formatos audiovisuales han postulado múltiples aproximaciones a la última dictadura cívico-militar, y de igual manera refirieron a las consecuencias y los resabios de ese tiempo histórico en las décadas subsiguientes. En ese amplio conglomerado audiovisual, las realizaciones cinematográficas provenientes de diferentes puntos de nuestro país fueron marcando perspectivas canónicas, discordantes y/o de ruptura sobre estas problemáticas, al igual que acompañaron el proceso de Memoria, Verdad y Justicia que se inauguró en la Argentina a partir de la recuperación de la democracia en 1983. En primera instancia, con el objetivo de confirmar el estatuto ideológico-expresivo que distinguió a una serie acotada pero significativa de films que versaron en torno a estos tópicos y que fueron realizadas en diferentes épocas históricas, el artículo dará cuenta de las características nodales de esos films que establecieron rupturas débiles o cruciales desde el punto de vista cinematográfico, al igual que en sus apuestas temáticas e ideológicas. En segundo lugar, se analizará el film Camuflaje (Jonathan Perel, 2022), profundizando en las búsquedas narrativas y representacionales que implican un nuevo giro en las interpretaciones del pasado reciente y en la producción de memoria. Se tendrá en cuenta, en particular, la colaboración de secuencias que tienden al dinamismo o bien al estatismo, la oscilación entre la primera y la tercera persona narrativa y las reflexiones en torno a la convivencia de lo ominoso y la vida cotidiana o corriente. De igual modo, se realizará una evaluación global de los aportes intrínsecos de Camuflaje y se examinarán las relaciones de proximidad y/o de distanciamiento que mantiene con las vertientes cinematográficas que le preceden.Identificador permanente (ARK):   http://id.caicyt.gov.ar/ark:/s18535925/uux6q8aug
Impacts of Soil Health Practices on Hydrologic Processes
Authors: Wyatt Briana , Arenas Antonio , Birgé Hannah , Hatfield Jerry , Lal Rattan , Schnitkey Gary , Wacha Ken
Published: June 2024

This paper explores the growing interest in soil health, emphasizing its importance in optimizing crop production, ecosystem function, and biodiversity. Defined by the USDA-NRCS as the soil’s capacity to function as a vital ecosystem, soil health involves filtering contaminants, cycling nutrients, supporting infrastructure, and regulating water movement. Traditional approaches to quantifying soil health focus on chemical, physical, or biological properties, often calling for a more integrated measurement method. While practices enhancing soil health, such as no-tillage, cover crops, and biodiversity, have long been promoted, their broader impacts on the hydrologic cycle are less documented. This paper aims to fill this gap by reviewing the literature on soil health practices’ effects on the hydrologic cycle and providing evidence and guidelines for policy- and decision-makers. It highlights the benefits of improved soil health, including increased water infiltration, higher crop yields, and reduced greenhouse gas emissions.
Implementación de la justicia restaurativa en el sistema penal ecuatoriano: un enfoque sistemático
Authors: Salinas Morocho Natalia Alejandra
Published: June 2024

The objective of this article is to carry out a systematic review of the implementation of restorative justice in the context of the Ecuadorian criminal system. Fundamental aspects will be addressed, including its legal framework, the approaches adopted, the results obtained and the challenges faced in practice. This study seeks to understand and critically evaluate the effectiveness and impact of restorative justice in the judicial system of Ecuador, exhaustively analyzing the policies, programs and procedures applied in this area.
Hugo Zemelman's proposal in the curriculum for basic education in Mexico, 2022
Authors: López-Pérez Sócrates , Martínez-López Juan Pablo
Published: June 2024

The following essay seeks to account for the theoretical construction proposed by the Basic Education Plan with respect to the Training Field, this being the third step through which teachers must go through to build their programs, this has the function of being the social, cultural, political, productive and symbolic space in which the school is part. The proposal is based on various theoretical postulates, so this text will focus on understanding the importance of Hugo Zemelman's concept of Historical Subject and Construction of Reality in the Training Field. Therefore, in the first instance the Basic Education Plan was analyzed, emphasizing the Formative Field proposal based on Hugo Zemelman, in a second instance works by this author were analyzed from two categories of analysis: Historical Subject and Construction of reality.
Editorial
Authors: León González Jorge Luis
Published: June 2024

El enfoque de convergencia de la ciencia surge como un paradigma a utilizar en la investigación, científica para obtener nuevos conocimientos que permitan desarrollar nuevas soluciones. La mayoría de las soluciones y tecnologías actuales se han obtenido gracias a procesos de Investigación, Desarrollo e Innovación (I+D+i).
La I+D+i es la unión de términos que parten de distintas ramas del conocimiento: investigación de la ciencia, desarrollo de la economía e innovación de la tecnología. De manera que la Investigación, es el proceso mediante el cual diferentes profesionales de cualquier sector construyen nuevos conocimientos para darle soluciones a diferentes problemáticas que se les presenta en su contexto. soluciones. Se invierte dinero y recursos con el objetivo de obtener nuevos conocimientos. 
En el Desarrollo, se emplean técnicas ya existentes con el objetivo de crear nuevas soluciones a las diferentes problemáticas. Se utilizan los conocimientos obtenidos en la parte de la investigación como punto de partida. 
Mientras que la Innovación, es un proceso más creativo y relacionado con la ciencia y la tecnología; donde además de la innovación tecnológica se desarrolla también la innovación social. Es decir, a través de procesos de I+D+i en el ámbito social se logra una mejoría en los procesos cotidianos que configuran la sociedad. De acuerdo con el Índice Mundial de Innovación de 2023: Suiza, Suecia y los Estados Unidos lideran la clasificación mundial de innovación.
De esta forma, la convergencia de la ciencia con una visión multidisciplinaria, desde la perspectiva de Investigación, Desarrollo e Innovación (I+D+i), busca orientar la investigación científica en los diversos campos de aplicación para impulsar la sociedad y mejorar la calidad de vida de las personas.
En el número que se presenta de la Revista Metropolitana de Ciencias Aplicadas (REMCA, se ofrecen algunas aportaciones con una visión multidisciplinaria de la ciencia que logran solucionar los problemas sociales que se presentan en diferentes contextos.
Strategies for socialization in children with autism spectrum disorder at home and in the classroom
Authors: Martín-Pinto Oscar José
Published: June 2024

This essay focuses on describing and explaining how socialization was achieved in elementary school students with TEA, it is known is a disorder that causes alterations in language, communication, social interaction and thought forms, so the biopsychosocial development of children is affected; The subjects described in this essay have a series of antecedents on the poor development of socialization, in order to solve this problem, the objective of being able to create or replicate existing strategies for the development of communication and therefore, socialization, arose. carried out a methodology that consisted of conducting a bibliographic review to determine what strategies and techniques are used for this purpose. The results found were a series of strategies and techniques of multiple uses, which begins with physical and psychological actions to begin processes of communication, integration and group coexistence. The conclusions obtained were the achievement and progress of the communication guidelines, which also led to the development of socialization and coexistence with their peers.
Estudio doctrinario del desempleo, el efecto socio-jurídico de política pública que vulnera el derecho al trabajo en pandemia por COVID-19
Authors: Reyes-Moreno Yustin Guillermo , Morocho-Bustamante Nathaly Elizabeth , Ramírez-López Guido Miguel
Published: June 2024

The research presented addresses the consequences derived from the public policy implemented during the COVID-19 pandemic. The concern arises from the need to provide elements in order to find an effective way to treat unemployment, which should be done from a legal perspective where it is possible to rethink public policies with a view to promoting economic recovery and the transformation of development models, which can consequently generate jobs and, in turn, reduce unemployment rates. The documentary research method of the bibliographic type was applied, analysis of the doctrine and legal regulations were carried out, especially public policies focused on the subject of study and as a technique the use of secondary data.