bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review on Imbalanced Data Challenges in Machine Learning
Authors: Kaur Harsurinder , Pannu Husanbir Singh , Malhi Avleen Kaur
Published: September 2019

In machine learning, the data imbalance imposes challenges to perform data analytics in almost all areas of real-world research. The raw primary data often suffers from the skewed perspective of data distribution of one class over the other as in the case of computer vision, information security, marketing, and medical science. The goal of this article is to present a comparative analysis of the approaches from the reference of data pre-processing, algorithmic and hybrid paradigms for contemporary imbalance data analysis techniques, and their comparative study in lieu of different data distribution and their application areas.
miR-221 Alleviates the Ox-LDL-Induced Macrophage Inflammatory Response via the Inhibition of DNMT3b-Mediated NCoR Promoter Methylation
Authors: Ye Jinshan , Wu Yaxi , Guo Ruiwei , Zeng Wenjun , Duan Yanan , Yang Zhihua , Yang Lixia
Published: September 2019

Atherosclerosis (AS) is a chronic inflammatory disease, and macrophages play a key role in all phases of AS. Recent studies have shown that miR-221 is a biomarker for AS and stroke; however, the role and mechanism of miR-221 in AS are unclear. Herein, we found that miR-221 and NCoR levels were decreased in ox-LDL-treated THP-1-derived macrophages. In contrast, DNMT3b, IL-6, and TNF-αexpression levels were increased under these conditions. Upregulation of miR-221 or NCoR could partially inhibit ox-LDL-induced IL-6 and TNF-αexpression. Further studies showed that DNMT3b was a target of miR-221. DNMT3b inhibition also suppressed IL-6 and TNF-αexpression and increased NCoR expression in the presence of ox-LDL. Moreover, DNMT3b was involved in ox-LDL-induced DNA methylation in the promoter region of NCoR. These findings suggest that miR-221 suppresses ox-LDL-induced inflammatory responses via suppressing DNMT3b-mediated DNA methylation in the promoter region of NCoR. These results provide a rationale for using intracellular miR-211 as a possible antiatherosclerotic target.
External Oblique Muscle Schwannoma: A Rare Anatomical Presentation
Authors: Paramythiotis Daniel , Pagkou Diamantoula , Moysidis Moysis , Mantha Niki , Cheva Angeliki , Michalopoulos Antonios
Published: September 2019

Introduction. Schwannomas or neurilemmomas are rare, benign, and usually solitary lesions that arise from the nerve sheath. In the majority of cases, these tumors involve the extremities, head, neck, and trunk. Case Presentation. In the present study, a 52-year-old man presented to our surgical department for the evaluation of a symptomatic lump in his left lateral abdominal wall. CT and MRI confirmed the presence of a cystic mass located between the external and internal oblique muscles. Histopathology and immunohistochemistry confirmed it to be benign schwannoma. Discussion. Schwannomas have rarely been reported in the abdominal wall. To the best of our knowledge, this is the first case of schwannoma located in the left upper abdominal wall and the fifth case of abdominal wall schwannoma reported according to the reviewed medical literature. Conclusion. Benign schwannoma should be included in the differential diagnosis of cystic and symptomatic lesions of the abdominal wall. The treatment of choice is surgical excision, and recurrence is extremely rare.
Estimating Uterine Fibroid SNP-Based Heritability in European American Women with Imaging-Confirmed Fibroids
Authors: Bray Michael J. , Davis Lea K. , Torstenson Eric S. , Jones Sarah H. , Edwards Todd L. , Velez Edwards Digna R.
Published: September 2019

Background: Heritability estimates (including twin and single nucleotide polymorphism [SNP]-based heritability studies) for fibroids have been inconsistent across prior studies ranging between 9 and 69%. These inconsistencies are due to variations in study design and included populations. A major design issue has been lack of imaging confirmation to identify controls, where asymptomatic women without imaging confirmation may be misclassified as controls leading to an attenuation of heritability estimates. To reconcile the differences in prior heritability estimates and the impact of misclassification of controls on heritability, we determined SNP-based heritability and characterized the genetic architecture of pelvic image-confirmed fibroid cases and controls. Methods: Analyses were performed among women of European American descent using genome-wide SNP data from BioVU, a clinical database composed of DNA linked to de-identified electronic health records. We estimated the genetic variance explained by all SNPs using Genome-Wide Complex Trait Analysis on imputed data. Fibroid cases and controls were identified using a previously reported phenotyping algorithm that required pelvic imaging confirmation. Results: In total, we used 1,067 image-confirmed fibroid cases and 1,042 image-confirmed fibroid controls. The SNP-based heritability estimate for fibroid risk was h2 = 0.33 ± 0.18 (p = 0.040). We investigated the relationship between heritability per chromosome and chromosome length (r2 < 1%), with chromosome 8 explaining the highest proportion of variance for fibroid risk. There was no enrichment for intergenic or genic SNPs for the fibroid SNP-based heritability. Excluding loci previously associated with fibroid risk from genome-wide association study did not attenuate fibroid heritability suggesting that loci associating with fibroid risk are yet to be discovered. Conclusions: We observed that fibroid SNP-based heritability was higher than the previous estimate using genome-wide SNP data that relied on self-reported outcomes, but within the range of prior twin pair studies. Furthermore, these data support that imprecise phenotyping can significantly affect the ability to estimate heritability using genotype data.
Impact of Early Vitrectomy for Dense Vitreous Hemorrhage of Unknown Etiology
Authors: Hayashida Mayuka , Miki Akiko , Imai Hisanori , Otsuka Keiko , Azumi Atsushi , Nakamura Makoto
Published: September 2019

Background: Surgical intervention for dense vitreous hemorrhage (DVH) with unclear etiology is often delayed in favor of conservative follow-up despite possible disease progression and the availability of safe minimally invasive vitrectomy. Objectives: The aim of this study is to investigate the efficacy of early surgical intervention for DVH with unknown etiology. Methods: Eighty-eight cases (88 eyes) of DVH with unknown origin were retrospectively reviewed. Inclusion criteria were as follows: (1) measured visual acuity (VA) of 20/200 or worse and (2) fundus invisibility requiring B-scan ultrasonography. Eyes with a history of diabetic retinopathy, recent trauma, or likely retinal detachment (RD) as revealed by B-scan ultrasonography were excluded. Outcome measures were a cause of vitreous hemorrhage and final VA following early (≤2 weeks after symptom onset) or delayed vitrectomy. Results: The most frequently occurring causes of DVH were central or branch retinal vein occlusion (30 eyes, 34%) and retinal tear or RD (29 eyes, 33%). logMAR VA significantly improved after treatment (p < 0.001). Final VA was significantly higher for eyes treated within 2 weeks compared with eyes treated later than 2 weeks after symptom onset (p = 0.020). Conclusions: Surgical intervention within 2 weeks after symptom onset may prevent a lower visual outcome.
Moving Beyond the Dyad: Broadening Our Understanding of Family Conflict
Authors: Persram Ryan J. , Scirocco Alyssa , Della Porta Sandra , Howe Nina
Published: September 2019

The family represents a set of interconnected relationships, characterized by high levels of intimacy and closeness, which also provide opportunities for family conflict. In the literature, there appears to be a shift in understanding of what family conflict is and its subsequent consequences. Previous research focuses on dyadic family conflicts and often views it as a negative experience, resulting in the study of various maladaptive outcomes including internalizing and externalizing behaviour problems. Recently, researchers argue that family conflict should be operationalized to include more than two individuals. Further, evidence suggests that experience in conflict offers children a unique context to hone their social and cognitive skills. This review explores how research on family conflict has evolved. We investigate the status of the field by specifying that family conflict should include instances where more than two members are involved, how theories can be bridged to support this claim, and why it is also necessary to view family conflict as a positive experience. Lastly, we discuss key methodological and analytical issues as well as possible interventions that would help disentangle the inherent complexity of studying family conflict. We emphasize the implications of advancing the field for researchers and frontline professionals.
Post-Myelofibrosis Acute Myeloid Leukemia Effectively Treated with a Combination of Ruxolitinib and 5-Azacytidine
Authors: Diamantopoulos Panagiotis T. , Giannakopoulou Nefeli , Hatzidavid Sevastianos , Viniou Nora-Athina
Published: September 2019

Background: Leukemic transformation is an unfavorable event emerging in a minority of patients with myelofibrosis (MF) and carrying a poor prognosis. Patients with post-MF acute myeloid leukemia (AML) may be treated with curative or noncurative intent, but there is no standard of care. The use of hypomethylating agents has been correlated with limited activity and low overall survival rates, while ruxolitinib has been proven to have modest antileukemic activity. Case Presentation: In this case study, we present the case of a 67-year-old female patient with post-polycythemia vera MF who developed AML and was successfully treated with a combination of 5-azacytidine and ruxolitinib, without any significant toxicity. Summary: To our knowledge, this is the first report of a patient with post-MF AML achieving a complete remission with a combination of ruxolitinib and a hypomethylating agent. This combination is actively studied in phase I/II clinical trials and may be proven effective in this hard-to-treat group of patients.
Uveitis unter Nivolumab: Ein Unglück kommt selten allein …
Authors: Pleyer Uwe
Published: September 2019

Nivolumab is an anti-programmed cell death protein 1 monoclonal antibody that is used to treat metastatic cutaneous malignant melanoma. Although bilateral uveitis has been reported as a side effect of nivolumab administration, there are few reports of Vogt-Koyanagi-Harada disease (VKH)-like uveitis. We report such a case. A 63-year-old woman with metastatic cutaneous malignant melanoma experienced visual loss in both eyes 10 days after her second nivolumab injection. Her decimal best-corrected visual acuity (BCVA) was 0.7 in the right eye and 0.4 in the left eye. Examination revealed bilateral granulomatous keratic precipitates and posterior synechiae in the left eye. Optical coherence tomography showed multiple sites of serous retinal detachment (SRD) in the left eye and wavy retinal pigment epithelium in both eyes. Fluorescein angiography revealed multiple pinpoint-sized areas of leakage in both eyes and active leakage from the disc in her right eye. Indocyanine green angiography (IA) showed choroidal hyperfluorescence due to choroidal vascular leakage, with hypofluorescent dark spots during the late phase. These findings supported a diagnosis of VKH-like uveitis following nivolumab injections. Nivolumab was discontinued because of headache. Anterior chamber inflammation disappeared 3 weeks after starting topical corticosteroid treatment, and the SRD disappeared within 3 months. Her decimal BCVA recovered to 1.0 in the right eye and to 0.9 in the left eye. Also, the fluorescein angiography and IA findings had improved by 4 months. We concluded that careful follow-up is required after nivolumab treatment because VKH-like panuveitis might develop.
Prävalenz retinaler Venenverschlüsse in Europa: Aufruf zu mehr Datenerfassung
Authors: Feltgen Nicolas
Published: September 2019

Purpose: The aim of this study was to examine the prevalence and incidence of retinal vein occlusions (RVO) in Europe. Methods: A systematic review and meta-analysis of the prevalence and incidence of RVO in Europe according to the Meta-Analyses of Observational Studies in Epidemiology (MOOSE) guidelines was performed in the databases PubMed, Embase and Web of Science. Based on Eurostat data, the total number of affected individuals in the EU was calculated and projected to the year 2050. Results: The random-effects pooled prevalence of RVO in Europe was 0.7% (95% CI: 0.5-0.9%) in persons aged 55 years and older based on the examination of 25,002 individuals from 4 prevalence studies. No European incidence studies were identified. The total number of affected individuals in the EU was estimated to rise by almost 20% from 900,000 today to 1.1 million in 2050. Conclusion: Published articles on the prevalence and incidence of RVO in Europe are limited. With the expected increase in affected persons, further epidemiological research is warranted for adequate healthcare planning.
Crizotinib-Associated Renal Cysts in Anaplastic Lymphoma Kinase-Positive Lung Cancer Patients: A Single-Center Experience
Authors: Eiamprapaporn Panuch , Mungwatthana Naphapatt , Twinprai Prin , Sookprasert Aumkhae , Chindaprasirt Jarin , Ahooja Anucha , Watthanaudomrot Sirinthip , Sirithanaphol Wichien
Published: September 2019

Crizotinib is an anaplastic lymphoma kinase (ALK) inhibitor that was approved for ALK-harboring lung cancer. There have been reports about the development and progression of renal cysts from crizotinib. We report a series of 3 cases of crizotinib-associated renal cysts in patients admitted to our institution, with different kinds of presentation. A monitor for complex renal cysts is warranted in patients receiving crizotinib.
CPC e MST
Authors: Bôas Rafael Litvin Villas
Published: September 2019

O artigo tem como objetivo refletir sobre as condições de produção e sobre a evolução das formas a partir da experiência concreta de trabalho teatral, articuladas à demandas de organizações políticas, considerando as experiências dos anos 1960, em particular do Centro Popular de Cultura da União Nacional dos Estudantes, em chave comparativa com a experiência teatral desenvolvida pelo Movimento dos Trabalhadores Rurais Sem Terra e coletivos de teatro a ele vinculados. O argumento visa articular a narrativa das experiências com o esforço editorial de divulgar o trabalho de teóricos, diretores e de organizações emblemáticas do teatro político brasileiro e internacional, e pretende apontar características semelhantes entre as organizações, a despeito das diferenças de contextos, que sinalizam providências de construção de uma cultura política popular no Brasil.
O livro Carmelo Bene – Lectura Dantis como testemunho de um acontecimento
Authors: Balestreri Silvia
Published: September 2019

Resenha de Carmelo Bene – Lectura Dantis: cronaca e testimonianze di un grande evento, organizado por Rino Maenza. O livro apresenta, com relatos, fragmentos de jornais da época e o encarte com um DVD, uma participação arrebatadora de Carmelo Bene (1937-2002) no primeiro aniversário daquele que foi o mais sangrento massacre acontecido na Itália nos chamados “anos de chumbo”, em que grupos de extrema direita e de extrema esquerda se lançaram em ações de sequestro e atentados, assombrando a rotina das principais cidades da península.
O vanguardismo no calor dos trópicos
Authors: Leão Howardinne Queiroz
Published: September 2019

Este artigo visa discutir as transformações teatrais na década de 1960 sob a perspectiva do Teatro Experimental do Serviço Social do Comércio do Amazonas (Sesc-AM), popularmente conhecido como Tesc (1968-2016), refletindo o início de grandes contribuições no cenário artístico de Manaus. Seus primeiros trabalhos manifestam a prática de um vanguardismo experimental de resistência, estruturando a modernização teatral no Amazonas. A bibliografia dialoga com autores importantes da cena teatral nortista como Selda Vale, Ediney Azancoth e Márcio Souza.
Imagens de 1968
Authors: Yoshioka Hiroto
Published: September 2019

Fotos feitas por Hiroto Yoshioka da Batalha da Maria Antônia
Entrevista com Iná Camargo Costa – De derrota em derrota, a luta continua
Authors: Carbone Roberta , Cosmo Matheus
Published: September 2019

Entrevista realizada em 10 de julho de 2018, por Matheus Cosmo e Roberta Carbone.
Effect of Systolic Blood Pressure on Left Ventricular Structure and Function
Authors: Hendriks Tom , Said M. Abdullah , Janssen Lara M.A. , van der Ende M. Yldau , van Veldhuisen Dirk J. , Verweij Niek , van der Harst Pim
Published: September 2019

We aimed to estimate the effects of a lifelong exposure to high systolic blood pressure (SBP) on left ventricular (LV) structure and function using Mendelian randomization. A total of 5596 participants of the UK Biobank were included for whom cardiovascular magnetic resonance imaging and genetic data were available. Major exclusion criteria included nonwhite ethnicity, major cardiovascular disease, and body mass index >30 or <18.5 kg/m
2
. A genetic risk score to estimate genetically predicted SBP (gSBP) was constructed based on 107 previously established genetic variants. Manual cardiovascular magnetic resonance imaging postprocessing analyses were performed in 300 individuals at the extremes of gSBP (150 highest and lowest). Multivariable linear regression analyses of imaging biomarkers were performed using gSBP as continuous independent variable. All analyses except myocardial strain were validated using previously derived imaging parameters in 2530 subjects. The mean (SD) age of the study population was 62 (7) years, and 52% of subjects were female. Corrected for age, sex, and body surface area, each 10 mm Hg increase in gSBP was significantly (
P
<0.0056) associated with 4.01 g (SE, 1.28;
P
=0.002) increase in LV mass and with 2.80% (SE, 0.97;
P
=0.004) increase in LV global radial strain. In the validation cohort, after correction for age, sex, and body surface area, each 10 mm Hg increase in gSBP was associated with 5.27 g (SE, 1.50;
P
<0.001) increase in LV mass. Our study provides a novel line of evidence for a causal relationship between SBP and increased LV mass and with increased LV global radial strain.
Decreased OLA1 (Obg-Like ATPase-1) Expression Drives Ubiquitin-Proteasome Pathways to Downregulate Mitochondrial SOD2 (Superoxide Dismutase) in Persistent Pulmonary Hypertension of the Newborn
Authors: Schultz Adam , Olorundami Olubunmi A. , Teng Ru-Jeng , Jarzembowski Jason , Shi Zheng-Zheng , Kumar Suresh N. , Pritchard Kirkwood , Konduri Girija G. , Afolayan Adeleye J.
Published: September 2019

Persistent pulmonary hypertension of the newborn (PPHN) is a failure of pulmonary vascular resistance to decline at birth rapidly. One principal mechanism implicated in PPHN development is mitochondrial oxidative stress. Expression and activity of mitochondrial SOD2 (superoxide dismutase) are decreased in PPHN; however, the mechanism remains unknown. Recently, OLA1 (Obg-like ATPase-1) was shown to act as a critical regulator of proteins controlling cell response to stress including Hsp70, an obligate chaperone for SOD2. Here, we investigated whether OLA1 is causally linked to PPHN. Compared with controls, SOD2 expression is reduced in distal-pulmonary arteries (PAs) from patients with PPHN and fetal-lamb models. Disruptions of the
SOD2
gene reproduced PPHN phenotypes, manifested by elevated right ventricular systolic pressure, PA-endothelial cells apoptosis, and PA-smooth muscle cells proliferation. Analyses of SOD2 protein dynamics revealed higher ubiquitinated-SOD2 protein levels in PPHN-lambs, suggesting dysregulated protein ubiquitination. OLA1 controls multiple proteostatic mechanisms and is overexpressed in response to stress. We demonstrated that OLA1 acts as a molecular chaperone, and its activity is induced by stress. Strikingly, OLA1 expression is decreased in distal-PAs from PPHN-patients and fetal-lambs. OLA1 deficiency enhanced CHIP affinity for Hsp70-SOD2 complexes, facilitating SOD2 degradation. Consequently, mitochondrial H
2
O
2
formation is impaired, leading to XIAP (X-linked inhibitor of apoptosis) overexpression that suppresses caspase activity in PA-smooth muscle cells, allowing them to survive and proliferate, contributing to PA remodeling. In-vivo, o
la1
−/−
downregulated SOD2 expression, induced distal-PA remodeling, and right ventricular hypertrophy. We conclude that decreased OLA1 expression accounts for SOD2 downregulation and, therefore, a therapeutic target in PPHN treatments.
On the Implausibility of Identifying the Disciple in John 18:15–16 as a Galilean Fisherman
Authors: Myles Robert J. , Kok Michael
Published: September 2019

John 18:15–16 mentions an unknown disciple of Jesus who “was known to the high priest” giving him access to the events in Caiaphas’s courtyard. A minority of scholars maintain the identity of this disciple is consistent with John, the son of Zebedee, whom they also maintain was the author of the Fourth Gospel. To support this position, the commonplace fiction of Galilean fishermen belonging to an aspiring “middle-class” is asserted. This article reviews the arguments and suggests that a more robust representation of class stratification in the ancient world demonstrates the implausibility of such a scenario.
A new mayfly species of Rhoenanthus (Ephemeroptera: Potamanthidae) from Peninsular India
Authors: BALASUBRAMANIAN CHELLIAH , MUTHUKATTURAJA MARIMUTHU , ANBALAGAN SANKARAPPAN
Published: September 2019

A new mayfly species, Rhoenanthus (Rhoenanthus) tungaiensis sp. nov. is described and characterized at the larval stage by fore tibiae relatively long with dense hair like setae on dorsal and lateral surface, male compound eyes large, mandibular tusks 0.8 times longer than head length, segment I of maxillary palpi 1.7 times longer than segment II, fore femur 2.9 times longer than its greatest width, gill III with 46–48 marginal fibrillae on lateral margin of dorsal lamellae and 35–37 on ventral lamellae. At the imaginal stage, the new species can be separated by inverted bell shaped markings on terga, purplish brown intercalaries in forewings, costal cross veins reddish brown and infuscated, MP2 connected to CuA basally.
Margins in Laryngeal Squamous Cell Carcinoma Treated with Transoral Laser Microsurgery: A National Database Study
Authors: Hanna Jonathan , Brauer Philip R. , Morse Elliot , Mehra Saral
Published: September 2019

Objectives

To determine national positive margin rates in transoral laser microsurgery, to compare patients with positive and negative margins, and to identify factors associated with positive margins.

Study Design

Retrospective review of the National Cancer Database.

Setting

Population based.

Subjects/Methods

Patients included those with TIS‐T3 laryngeal squamous cell carcinoma (2004‐2014). Univariable and multivariable logistic regression were used to identify predictors.

Results

A total of 1959 patients met inclusion criteria. The national positive margin rate was 22.3%. Sixty‐five percent of patients had T1 disease; 94.3% were N‐negative; and 74.0% had glottic tumors. Fifty‐eight percent of patients were treated at academic centers, and 60.6% were treated at facilities performing <2 cases per year. On multivariable analysis, factors associated with margin status included facility volume (odds ratio [95% CI]; in cases per year: 0.93 [0.89‐0.97], P =. 001), academic status (vs nonacademic; academic: 0.70 [0.54‐0.90], P =. 008), T‐stage (vs T1; T2: 2.74 [2.05‐3.65], T3: 5.53 [3.55‐8.63], TIS: 0.59 [0.38‐0.92], P <. 001), and N‐stage (vs N0; N1: 3.42 [1.79‐6.54], N2: 2.01 [1.09‐3.69], P <. 001). Tumor subsite was not associated with margin status.

Conclusion

The national positive margin rate for laryngeal laser surgery is 22%, which is concerning given the equivalent survival benefit offered by surgery and primary radiation and the increased likelihood of bimodal therapy in the situation of positive margins. Cases treated at nonacademic centers and those with lower caseloads had a higher likelihood of positive margins. There was a linear association between T‐stage and likelihood of positive margins, with T3 tumors being 5 times as likely as T1 to yield positive margins. This study highlights the importance of proper patient selection for transoral laser microsurgery resections.
Decolonising Cultural Studies
Authors: Sawhney Rashmi
Published: September 2019

Written as a reflective account emerging from the process of reviewing and revamping an MA in English and Cultural Studies at Christ (Deemed to be University), Bangalore, in the year 2018-19, this essay takes the form of a tapestry woven out of four separate but related inquiries. Section I reflects upon the experience of having taught introductory courses in Cultural Studies (henceforth CS) in India and Ireland separated by a gap of 15 years, and germane questions of cultural specificity and curricula. Section II provides an overview of the available narratives of CS within India, focusing on the distinctive approach taken in each account. Section III looks at the relationship between CS, Postcolonial Studies (henceforth PS) and Subaltern Studies (henceforth SS), as they developed in play with one another in 1980s England and America. And Section IV comments on some wider institutional and creative practices of relevance, and the implications these hold for possible future directions of CS. In totality, the article attempts to assess what transformative wor
Evolving Notions and Experiences of English Studies and Pedagogy in Contemporary India
Authors: Girish Urmila , Govind Nikhil
Published: September 2019

The article highlights how new sub-disciplines such as Malayalam literature are increasingly emerging as the mainstay of Literary studies in India. Though there is a debt to the British model that highlighted the canon from Chaucer to the twenty-first century, it has become increasingly clear that India will have to find its own understanding of what English Studies can best represent for contemporary Indian interests. Innovation will thus have to emerge both in terms of the content and a student-centred pedagogy. Shift in languages, with an increasing interest in gender, caste, visual culture has been an important step. In terms of pedagogy, negotiation between the need for articulations in mother tongue and English as a second language requires pedagogical reflections.
Dynamics in the Origins of Technological Knowledge in Early Firm Years: Implications for New Product Introductions
Authors: Hashai Niron , Zander Ivo
Published: September 2019

We document how, in the early years of high-technology firms, the origination of technological knowledge starts with firm founders, then shifts to other firm members, and, later on, shifts to external stakeholders. We further show that greater reliance on founder technological knowledge is initially positively but later on negatively associated with new product introductions, whereas the opposite relationship holds for reliance on firm member and external stakeholder technological knowledge. By assessing the dynamics and effects of technological knowledge origins on new product introductions, involving founders, firm members, and external stakeholders, we offer new empirical and theoretical insights pertaining to the role of technological knowledge in the growth of high-technology firms.
Superfícies/feminilidades: O imperceptível como estratégia sobre o olhar
Authors: Devulsky Amanda Brum de Moraes Ponce
Published: September 2019

Resumo: O artigo a seguir percorre o trabalho de diferentes autores para desenvolver uma reflexão que visa propor um território para um modo de olhar, praticar e existir em experiências estéticas que se dão na relação entre superfícies técnicas e conceitos políticos de feminilidade. Palavras-chave: Feminilidades. Imagem técnica. Estéticas. Processos artísticos contemporâneos. Abstract: The following article wanders between the work of different authors to develop a reflection that proposes a territory for a way of seeing, practicing and existing in aesthetic experiences that occur at the intersection of technical surfaces and political concepts of femininity.Keywords: Femininities. Technical image. Aesthetics. Contemporary artistic processes.
Interstícios da Matéria
Authors: Alves Pereira Anais
Published: September 2019

O artigo relaciona o conceito Ma e o interstício, em Aby Warburg, constituindo relações temporais e espaciais não-lineares entre o sertão brasileiro e o nordeste japonês. A partir da palavra Shizen, são discutidos os limites entre ser-humano e natureza, traçando um percurso em busca de compreender as fronteiras como intervalo que conecta opostos.  Palavras-chave: Ma. Natureza. Sertão. Fronteira.   ABSTRACT: The article relates the Ma concept and the interstice in Aby Warburg, constituting nonlinear temporal and spatial relations between the Brazilian sertão and the Japanese northeast. From the word Shizen, the boundaries between being-human and nature are discussed, tracing a path in search of understand the boundaries as an interval that connects opposites.  Keywords: Ma. Nature. Sertão. Boundaries.
Cair (recair) saltar
Authors: Seger Débora
Published: September 2019

A partir do conto Funes, o memorioso, de Jorge Luis Borges, busca-se compor relações entre imagem e trauma, utilizando-se, para tanto, da teoria desenvolvida por Maurice Blanchot e da psicanálise. No percurso do ensaio, são abordadas as experiências da insônia (e do sono), da memória, do sonho e da escrita. Palavras-chave: imagem, trauma, insônia, memória, sonho, escrita.  Abstract: From the story Funes, the memorious, by Jorge Luis Borges, we aim to compose relations between image and trauma, using, for that, the theory developed by Maurice Blanchot and the psychoanalysis. In the course of the essay, the experiences of insomnia (and sleep), memory, dream and writing are discussed.  Keywords: image, trauma, insomnia, memory, dream, writing.
A Petite Galerie, Franco Terranova e o circuito de arte no Rio de Janeiro, 1954-1988
Authors: Caspary Gabriela
Published: September 2019

Esta pesquisa propõe uma biografia da Petite Galerie (PG), galeria de arte que funcionou no Rio de Janeiro e em São Paulo entre 1954 e 1988, pontuada por um exame da trajetória de seu principal sócio, o marchand e escritor Franco Terranova (1923-2013).   Palavras chave: Petite Galerie, Franco Terranova, galeria de arte, circuito de arte, Rio de Janeiro  ABSTRACT  This research proposes a biography of the Petite Galerie (PG), an art gallery that operated in Rio de Janeiro and São Paulo between 1954 and 1988, punctuated by an examination of the trajectory of its main partner, the marchand and writer Franco Terranova (1923- 2013).   Key words: Petite Galerie, Franco Terranova, art gallery, art circuit, Rio de Janeiro
Mediação como atribuição de força a uma arte fraca
Authors: Queiroz Tania
Published: September 2019

Investiga a proximidade entre arte contemporânea e público - a relaçãoentre arte e vida - entendendo que é o que os distancia. Apresenta: rupturasprovocadas pela arte moderna sob a ótica de artistas da época; artistascontemporâneos cuja obra seja atravessada por outros campos; programaseducativos em instituições culturais; perfis de mediação para a arte hoje.Palavras-chave: Arte. Arte contemporânea. Ensino. Programas educacionais.Mediation as a strength’s attribution to a weak artAbstract: Investigates the proximity between contemporary art and public - artand life - understanding that as the reason of their distance. It presents: theruptures of modern art from its own artists perspective; contemporaneous artistswhose art works are corelated to other fields of knowledge; educational programsin cultural institutions; mediation’s profiles for the current art.
Holistic management of malignant wounds in palliative patients
Authors: Cornish Lynn
Published: September 2019

Malignant wounds are a complication of cancer, and usually occur in those individuals with advanced disease. When healing ceases to be the goal, treatment is centred around symptom control and improving quality of life. Caring for individuals with malignant wounds presents challenges for patients, their families and nurses alike. This article discusses the holistic management of malignant wounds, with an emphasis on the control of both physical and psychosocial symptoms of wound management, as well as the impact that this may have on all those involved. Common physical symptoms of malignant wounds include malodour, bleeding, pain, exudate and pruritis. Psychosocial symptoms may result in social isolation and depression. All these symptoms have a huge impact, not only on patients and their families, but also on healthcare professionals both during and after care. Managing these symptoms requires a multidisciplinary approach to facilitate the best possible outcomes for patients and their caregivers.
‘We behave like a family’
Authors: Rook Olivia
Published: September 2019

Charlotte Hughes (below), deputy manager of Portico Lodge, is our first early years professional to be interviewed in a series looking at best practice. She discusses blackberry picking and why sustainability is at the top of her setting's agenda.
Special educational needs must be identified and supported earlier
Authors: Nolan Jane
Published: September 2019

As more children with complex needs find themselves in mainstream education, it is crucial that trusts and schools provide guidance for all early years professionals.
Small world, big ideas
Authors: Rawstrone Annette
Published: September 2019

When your child is making dinosaurs stomp up the stairs or playing out scenes from real life with small figures or objects, they are engaging in small world play. Find out how you can support this type of play at home.
Bowled over
Authors: Clarke Jenni
Published: September 2019

The official rules of rounders can be simplified for young children, enabling them to learn the basics of the sport, be active, concentrate on developing their skills and, most of all, have fun with their friends.
Representações das figuras parentais e dor psicológica: Um estudo exploratório
Authors: Fragata Ana Sofia , Campos Rui C. , Baleizão Cristina
Published: September 2019

O objectivo deste estudo de cariz exploratório é testar, em adultos da comunidade, a relação entre representações das figuras parentais e dor psicológica. A amostra final é constituída por 164 participantes, com idades entre os 18 e os 65 anos, que responderam à Psychache Scale e ao Inventário para Aceder às Memórias de Infância Relativas às Práticas Parentais (EMBU) e, realizaram uma descrição livre de cada uma das figuras parentais. Estas descrições foram codificadas recorrendo à Escala de Diferenciação e Relacionamento (Escala DR). Os resultados mostraram que à excepção do nível DR para a descrição da figura materna, as restantes cinco variáveis, nível DR para a descrição da figura paterna, rejeição paterna, rejeição materna, sobreprotecção paterna e sobreprotecção materna, se correlacionam significativamente com a variável dor psicológica. Uma análise de regressão múltipla do tipo forward mostrou que as variáveis, nível DR para a descrição da figura paterna, rejeição paterna e sobreprotecção materna deram um contributo significativo para a previsão da dor psicológica, embora explicando uma percentagem baixa de variância da dor psicológica. Este modelo foi corroborado através de Modelação de Equações Estruturais. Os resultados são discutidos no âmbito da teoria psicanalítica e da perspectiva da aceitação-rejeição de Rohner.
PELAKSANAAN LAYANAN BIMBINGAN KEMANDIRIAN PADA EKS PSIKOTIK DI RUMAH PELAYANAN SOSIAL EKS PSIKOTIK HESTINING BUDI KLATEN
Authors: Eko Putro Hanif Sandya
Published: September 2019

Ex Psychotics are people who have experienced mental disorders and are declared cured of mental hospitals, but they do not have proper independence. Therefore, they need an independent guidance service. This research is intended to find out the process of implementing independence guidance services, supporting and inhibiting factors and the form of independence in ex psychotics at the Social Services House of the former Psychotic Hestining Budi Klaten This study uses a descriptive qualitative approach. The subjects of this study were four social workers and three beneficiaries selected using a purposive sampling technique at the Social Services House of the Former Psychotic Hestining Budi Klaten. With data collection techniques in the form of interviews, observation, and documentation. In testing the validity of data using source triangulation. While for data analysis techniques using several stages starting from data collection (data collection), data reduction (data reduction), presenting data (data display), and drawing conclusions (conclusion: drawing / verifying). The results of this study that the implementation of independence guidance services at the Social Services House of Ex-Psychotic Hestining Budi Klaten is carried out through several stages including (1) Planning, namely social workers determine in advance the material to be given to ex psychotics; (2) Implementation, namely the provision of material to ex psychotics starting from Daily Living Activist (DLA) guidance, physical guidance, mental guidance, social guidance, and skills guidance; (3) Evaluation, namely giving an assessment from the results of the implementation of guidance; (4) Follow-up, which is the step to proceed to further guidance. Inhibiting factors in the implementation of independence guidance services such as facilities and infrastructure, Human Resources, ex-psychotic conditions, society, and difficulties in selling ex-psychotic works, while supporting factors start from the existence of good cooperation between social workers and outside parties/institutions, facilities and infrastructure, and family. The success of the independence guidance service process, namely ex psychotics is able to be independent in taking care of themselves, interact socially, carry out worship, and skills. Keyword: Independent guidence service, ex psikotik
ISLAM DAN PEACE BUILDING
Authors: Irawan Deni
Published: September 2019

Islam is the religion of dialogue that offers a variety of ways to create peace and harmony. Islam teaches compassion, tolerance, and the importance of friendship. Dialogue is a key concept in conflict resolution and peace building. This paper deeply discusses about dialogue in Islam as tool for building a peaceful civilization.
KONSTRUKSI JARINGAN SOSIAL PESANTREN: STRATEGI EKSIS DI TENGAH PERUBAHAN
Authors: Salehudin Ahmad
Published: September 2019

The perception that kyais are conservative, fanatic, and difficult to be invited in a dialogue will fade away when seeing the fact that their pesantrens are able to survive until today. Kyais are able to maintain pesantrens even though with traditional management, such as less of fundraising support and minimum facilitation. The pesantrens are still exist because they have capability to re- spond any changes and developments of  the world in their own way, which often difficult to be understood from modern logic. This paper explains how pesantrens develop and construct their social network as strateg y to exist in three ways: the transmission of  knowledge, marriage, and structure.
PENYALIBAN YESUS DALAM PERSPEKTIF PSIKOLOGIS UMAT KRISTEN DAN UMAT ISLAM
Authors: Anna Dian Nur
Published: September 2019

This article aims to understanding the crucifixion of Jesus according to bothChristians and Muslims in psychological perspective. This article try to illustrate how Christians and Muslims talk about the crucifixion of Jesus and the possibility to make an understandable between both religions. Christianity be-lieves that Jesus was dead on the cross for salvation. Islam, as a religion begin-ning after Christianity, also respects Jesus, especially the death of Jesus. Muslims have different opinions about the death of Jesus which divided them into two groups. The first group believes that Jesus did not crucify and did not die on the cross. The second groups of Muslims agree that Jesus crucified, but maintain that he did not die on the cross. Based on this article, it can know the meaning of crucifixion of Jesus from both Christians and Muslims in psychological perspective. For Christians, the mean-ing of crucifixion of Jesus is a proof of love and triumph of God. Jesus is an incarnation of God dead to redeem a great sin of human being and he was resurrected. For Muslims, the meaning of crucifixion of Jesus is a proof of love and triumph of God. God save Jesus from death on the cross with take Jesus beside God. Then, Muslims can understand how God sent Jesus as human to redeem human beings and God loves Jesus as a prophet with special status.
PERAN SOSIAL VIHARA BUDDHA PRABHA DALAM MEMELIHARA KERUKUNAN UMAT BERAGAMA DI YOGYAKARTA (STUDI PERAN ORGANISASI GENERASI MUDA CETIYA BUDDHA PRABHA [GMCBP] PERIODE 2016-2017)
Authors: Wijayanti Sekar
Published: September 2019

Yogyakarta disebut dengan kota toleransi, tetapi saat ini justru tingkat intoleran di Yogyakarta semakin tinggi. Hal ini dapat dilihat melalui berbagai kasus di Yogyakarta yang berlatarbelakang SARA, seperti penyerangan rumah ibadah, penutupan rumah ibadah, dan lain-lain. Salah satu cara untuk memelihara kerukunan umat beragama di Yogyakarta yaitu melalui peran sosial rumah ibadah. Vihara Buddha Prabha merupakan salah satu rumah ibadah di Yogyakarta yang memiliki peran sosial. Peran sosial Vihara Buddha Prabha yaitu sebagai tempat untuk menumbuhkan keharmonisan antar pemeluk agama dan memfasilitasi terwujudnya kerukunan umat beragama melalui berbagai macam kegiatan sosial. Kegiatan sosial di Vihara Buddha Prabha terbuka untuk masyarakat di Yogyakarta tanpa membeda-bedakan agama, suku, ras, dan budaya. Peran Vihara juga menunjukkan pada keterlibatan organisasi dalam melakukan usaha-usaha menciptakan kerukunan antar umat beragama melalui kegiatan vihara. Kegitan sosial yang terdapat di vihara diantaranya yaitu membersihkan vihara, talk show kesehatan bagi mahasiswa, donor darah, pembagian sembako, perpustakaan, dan meditasi. Melalui berbagai macam kegiatan sosial yang berhubungan dengan masyarakat dengan tidak membeda-bedakan agama, maka vihara mempunyai peran sosial sebagai salah satu solusi untuk mengatasi permasalahan sosial seperti kerukunan, ekonomi, pendidikan, dan lain-lain. Teori yang digunakan dalam penelitian ini yaitu menggunakan teori fungsionalisme Emile Durkheim.Kata Kunci : peran sosial, vihara, organisasi, dan kerukunan umat beragama
KEBERAGAMAAN MAHASISWA ALUMNI PONDOK PESANTREN Studi atas Konversi dan Apostasi Agama Mahasiswa Alumni Gontor di UIN Sunan Kalijaga Yogyakarta (Gorduka)
Authors: Rahayu Merliana Puji
Published: September 2019

Artikel ini membahas tentang perubahan keberagamaan mahasiswa alumni pondok pesantren, baik perubahan konversi agama maupun apostasi agama. Diskusi artikel ini berdasarkan temuan peneliti atas perubahan keberagamaan mahasiswa alumni pondok pesantren Gontor di UIN Sunan Kalijaga Yogyakarta. Ini sangat menarik ketika perubahan keberagamaan yang dialami oleh para mahasiswa alumni pondok pesantren Gontor, penulis menemukan ada 2 sisi, yaitu konversi agama (peningkatan religiusitas) dan apostasi agama (penurunan religiusitas). Pada perubahan itu terjadi dengan adanya proses perubahan yang dialami oleh para mahasiswa alumni pondok pesantren. Bukan hanya itu saja, banyak faktor yang mempengaruhi adanya perubahan keberagamaan, diantaranya faktor lingkungan, pertemanan, ekonomi, dan individu. Faktor-faktor tersebut dapat mempengaruhi mahasiswa Gorduka dari segi positif maupun negatif. Hingga mahasiswa Gorduka mengalami dua jenis perubahan keberagamaan yaitu konversi agama dan apostasi agama. Perubahan yang terjadi pada dasarnya kembali pada setiap masing-masing individu, maka adanya ketegasan dalam bersikap harus dapat diterapkan, agar tidak terlampau jauh mengalami perubahan kearah yang negatif. Mengingat Allah SWT dan perasaan dalam hati seseoranglah yang harus diperhatikan. Agar kehidupan yang dijalani menjadi tenang, damai, dan tentram.
DEWI IZANAMI DAN DEWA IZANAGI DALAM AGAMA SHINTO JEPANG (STUDI SEMIOTIK DALAM FILM NORAGAMI ARAGOTO)
Authors: Afrianti Muflikhatun
Published: September 2019

This study examines the mythology of Izanami Goddess and Izanagi God in Japanese Shinto religion and representations of Izanami Goddess and Izanagi God in the film Noragami Aragoto Adachitoka’s creation directed by Kotaro Tamura. This study is important because the story of Izanami Goddess and Izanagi God has never been adopted in modern scientific literature even though it has been listed in several anime in Japan. The research data was collected through documentation on the Kojiki and Nihonsoki books as well as capturing scenes of Noragami Aragoto films. Then analyzed using Christian Metz's language cinematography theory and Rudolf Otto's sacred theory. The results showed that firstly, based on the phenomenological perspective and sacrity from Rudolf Otto, Izanami Goddess and Izanagi God in Japanese Shinto mythology were the ancestors of the Mother and Father of the Gods and divine beings and played an active role in the creation of islands in Japan along with its contents. Secondly, in the Noragami Aragoto film, the perspective of cinematographic language Christian Metz, Izanami Goddess and Izanagi God are represented as mysteries of Father and Mother of Ebisu God (Hiruko) and Yaboku God (Awashima or Aha) with backgrounds that are very different from each other.Key Words: mythology, Shinto, Izanami, Izanagi, cinematographic language, and sacred.
De la société en jeu au jeu comme société : un parcours dialectique
Authors: Barnabé Fanny , Bazile Julien , Cayatte Rémi
Published: September 2019

Le présent numéro interroge le vaste champ des relations entre jeux vidéo et société, en prenant pour porte d’entrée la question – volontairement polysémique – suivante : « comment les jeux font-ils société ? ». La culture vidéoludique (ses œuvres et ses pra- tiques) s’inscrit toujours dans un contexte social donné qui en détermine largement le fonctionnement, les tensions internes, les évolutions, et qui, en retour, est lui-même représenté, travaillé, réfléchi par cette culture. Les relations et influences liant le jeu et le social peuvent donc prendre des visages multiples et des directions diverses, dont les textes de ce numéro rendent compte tant par la richesse de leurs objets que par la diversité de leurs approches. Nous tâcherons ici de retracer le parcours scientifique que ces regards croisés permettent d’effectuer : partant de la question de la place du jeu (et des joueurs·euses) dans la société contemporaine, nous passerons à celle de la représentation du social dans les jeux, pour enfin aborder la culture ludique comme étant, au-delà d’une figuration du social, un outil de médiation et de sociabilisation à part entière.
Comment les jeux font-ils société. Contenus, pratiques et médiations ludiques
Authors: Arsenault Dominic
Published: September 2019

À l’issue de ce numéro, nous avons choisi de laisser au professeur Dominic Arsenault toute latitude afin de proposer une conclusion « ludique ». Celle-ci offre à la fois la perspective d’un professeur en études du jeu vidéo (ou sciences du jeu dans le vocable européen) sur les travaux présents dans ce numéro, mais aussi le témoignage d’un chercheur de première génération dans le champ sur l’évolution de la recherche et sur les enjeux qui y sont attachés.
Qu’est-ce que l’hospitalité ? Recevoir l’étranger à la communauté (J. Stavo-Debauge, 2017)
Authors: Doytcheva Milena
Published: September 2019

Recensé : Joan Stavo-Debauge, Qu’est-ce que l’hospitalité ? Recevoir l’étranger à la communauté, Montréal, Éditions Liber, 2017, 315 p.