bluuebunny/crossref_metadata_2025 huggingface dataset:
Drosophila danyis essential for transcriptional control and nuclear architecture in spermatocytes
Authors: Trost Martina , Blattner Ariane C. , Leo Stefano , Lehner Christian F.
Published: July 2016

The terminal differentiation of adult stem cell progeny depends on transcriptional control. A dramatic change in gene expression programs accompanies the transition from proliferating spermatogonia to postmitotic spermatocytes, which prepare for meiosis and subsequent spermiogenesis. More than a thousand spermatocyte-specific genes are transcriptionally activated in early Drosophila spermatocytes. Here we describe the identification and initial characterization of dany, a gene required in spermatocytes for the large-scale change in gene expression. Similar to tMAC and tTAFs, the known major activators of spermatocyte-specific genes, dany has a recent evolutionary origin, but it functions independently. Like dan and danr, its primordial relatives with functions in somatic tissues, dany encodes a nuclear Psq domain protein. Dany associates preferentially with euchromatic genome regions. In dany mutant spermatocytes, activation of spermatocyte-specific genes and silencing of non-spermatocyte-specific genes are severely compromised and the chromatin no longer associates intimately with the nuclear envelope. Therefore, as suggested recently for Dan/Danr, we propose that Dany is essential for the coordination of change in cell type-specific expression programs and large-scale spatial chromatin reorganization.
Modeling Multimodal Continuous Heterogeneity in Conjoint Analysis—A Sparse Learning Approach
Authors: Chen Yupeng , Iyengar Raghuram , Iyengar Garud
Published: July 2016

Consumers’ preferences can often be represented using a multimodal continuous heterogeneity distribution. One explanation for such a preference distribution is that consumers belong to a few distinct segments, with preferences of consumers in each segment being heterogeneous and unimodal. We propose an innovative approach for modeling such multimodal distributions that builds on recent advances in sparse learning and optimization. We apply the model to conjoint analysis where consumer heterogeneity plays a critical role in determining optimal marketing decisions. Our approach uses a two-stage divide-and-conquer framework, where we first divide the consumer population into segments by recovering a set of candidate segmentations using sparsity modeling, and then use each candidate segmentation to develop a set of individual-level heterogeneity representations. We select the optimal individual-level heterogeneity representation using cross-validation. Using extensive simulation experiments and three field data sets, we show the superior performance of our sparse learning model compared to benchmark models including the finite mixture model and the Bayesian normal component mixture model.

Data, as supplemental material, are available at http://dx.doi.org/10.1287/mksc.2016.0992 .
Channel Integration, Sales Dispersion, and Inventory Management
Authors: Gallino Santiago , Moreno Antonio , Stamatopoulos Ioannis
Published: July 2016

We study the effects of the introduction of cross-channel functionalities on the overall sales dispersion of retailers and the implications of these effects for inventory management. To do that, we analyze data from a leading U.S. retailer who introduced a “ship-to-store” (STS) functionality that allows customers to ship products to their local store free of charge when those products are not available in their local store. Based on the fact that stores prioritize carrying products for which local demand is high, we test the hypothesis that introducing the STS functionality increased the retailer’s overall sales dispersion. We find that, on average, the contribution of the 90% lowest-selling products to total sales increased by 0.75 percentage points, increasing sales dispersion. Calibrating conventional inventory-ordering models, we show that to respond optimally to the observed increase in dispersion, the retailer would need to increase its cycle and safety inventories by approximately 2.7%. Our paper points out the effect of an increasingly important retail phenomenon (channel integration) on a key factor for inventory management (sales dispersion).

This paper was accepted by Vishal Gaur, operations management.
Investor Horizon and the Life Cycle of Innovative Firms: Evidence from Venture Capital
Authors: Barrot Jean-Noël
Published: July 2016

This paper studies whether and how the contractual horizon of venture capital funds affects their investments in innovative firms. I find that funds with a longer remaining horizon select younger companies at an earlier stage of their development, which grow their patent stock significantly more than companies financed by funds with a shorter horizon. The sensitivity of investment decisions to horizon is stronger among experienced venture capital firms, who allocate investments across a larger number of fund vintages. Finally, I find that the interaction of funds’ fixed horizon with their option-like compensation structure affects their investment decisions: when early performance has been high, fund managers target less innovative companies. These findings shed light on the drivers of venture capital investment decisions and on their implications for the type of companies that receive venture capital financing.

This paper was accepted by Gustavo Manso, finance.
Subgame-Perfect ϵ-Equilibria in Perfect Information Games with Common Preferences at the Limit
Authors: Flesch János , Predtetchinski Arkadi
Published: July 2016

We prove the existence of a pure subgame–perfect epsilon–equilibrium, for every epsilon > 0, in multiplayer perfect information games, provided that the payoff functions are bounded and exhibit common preferences at the limit. If, in addition, the payoff functions have finite range, then there exists a pure subgame–perfect 0–equilibrium. These results extend and unify recent existence theorems for bounded and semicontinuous payoffs.
Debates teóricos no campo das Relações Internacionais na China | Theoretical Debates in the Field of International Relations in China
Authors: Montenegro Renan Holanda
Published: July 2016

Este trabalho tem o objetivo de apresentar um panorama sobre a evolução do campo das Relações Internacionais na China e os debates recentes em torno do desenvolvimento de uma escola teórica autônoma que incorpore elementos da cultura chinesa. Neste debate, duas principais correntes têm se posicionado em lados opostos: a “Chinese School” e a “Tsinghua School”. O presente artigo descreve as diferenças entre essas escolas e discute as contribuições de cada uma para a elaboração de uma teoria chinesa das Relações Internacionais.ABSTRACTThis paper aims to present an overview about the evolution of the field of International Relations in China and the recent debates on the development of an autonomous theoretical school that incorporates elements of Chinese culture. In this debate, two main trends have positioned themselves on opposite sides: "Chinese School" and "Tsinghua School". This article describes the differences between these schools and discusses the contributions of each to the development of a Chinese theory of International Relations. Palavras-chave: China; Teoria; Relações Internacionais.Keywords: China; Theory; International Relations.  DOI: 10.12957/rmi.2015.18387  Recebido em 28 de agosto de 2015 / Aceito em 01 de dezembro de 2015.Received on August 28, 2015 / Accepted December 01, 2015.
Rent, lease or buy? How to finance your new equipment
Authors: Bernstein Adam
Published: July 2016

Choosing between renting, buying and leasing new equipment is always a difficult choice. Adam Bernstein provides an insight into the benefits and drawbacks of each of these three ways of financing your assets and day-to-day equipment
Regulatory pressure on providers persists
Authors: Adamson Rachel
Published: July 2016

The financial pressure in the adult social care sector remains at a critical level. With budgets being cut and residential homes failing inspections, Rachel Adamson discusses how this pressure is affecting the state of care in the UK
Why social care matters: the next 5 years
Authors: Frankova Helena
Published: July 2016

Social care provides for a large number of people living in the UK. However, the modern needs are ever-changing, and the care sector is now facing multiple new challenges. Helena Frankova discusses these issues, and how they will affect us over the next 5 years
Individualised values of happiness: exploring changing ethics in young people’s dating and relationships in post-reform China
Authors: Yang Chao
Published: July 2016

This article examines the changing ethics in dating and personal relationships of a group of young Chinese people born at the beginning of the economic reform era (1978 to present), which feeds into a broader project of investigating the romantic subjectivity of Chinese youth facing sociocultural change in the post-reform era. Based on data generated in semi-structured interviews, an emerging individualised and private personal ethics is observed, which challenges the monopoly of marriage towards sexual practices, and connotes a changing sexuality emphasising the fulfilment of sexual pleasure rather than procreation purposes. Chinese youth often embrace individual freedoms and choices facilitated by the free market economy and consumerist culture, while at the same time draw on (a sometimes new understanding of) traditional familial values in order to pursue personal happiness in a modernising society and gain an identity as Chinese in a globalising era.
Video Games: A Paradoxically Painful Art Form?
Authors: Feleki Despoina Nikolaos
Published: July 2016

Review of Jesper Juul, The Art of Failure: An Essay on the Pain of Playing Video Games. Cambridge, MA:  The MIT Press, 2013, 176 pp. ISBN 978-0262019057.
An Interdisciplinary Model of Context Morphology
Authors: Pál Dániel Levente , Daróczy Bálint
Published: July 2016

Using an abstract graph model we describe a hypothetical transformation of a literary entity through the active connections in the graph. First, we weakly define a set of transformations (“morphology”) over a particular entity as a series of the recent activities distinguishing them into categories according to their effect on the entity. Second, to our conjecture, the emerging paths of forms are slowly abandoning the original “birth context”, shaping a decreased, cleaned set of entities, to replace the gap with entities derived from the dynamic set of “recipient context”.
La reducción enunciativa: Podemos y la constricción de la voz de la multitud
Authors: Palao Errando José Antonio
Published: July 2016

La irrupción política de Podemos en el panorama mediático y electoral español ha supuesto no sólo una revolución política sino también comunicativa. El 15M significó la crisis definitiva de la hegemonía indiscutible del Modelo Difusión en política, como ya se había verificado en otros espacios de comunicación social. Con su “no nos representan”, el 15M fue ante todo un proceso de disolución enunciativa. Tras él Podemos es el único caso de un experimento de hibridación integral del Modelo Difusión y el Modelo Reticular, intentando propiciar su sinergia. El desembarco de Pablo Iglesias en la televisión resulta crucial, pues se trata de un intento de abrochar la enunciación mediático-electoral con la enunciación popular-reticular.
How to measure interconnectedness between banks, insurers and financial conglomerates
Authors: Hauton Gaël , Héam Jean-Cyprien
Published: July 2016

Financial institutions’ interconnectedness is a key component of systemic risk. However there is still no consensus on its measurement.
Using a unique database of network of exposures of French financial institutions, we compare three strategies to measure interconnectedness: closeness of exposure distributions, identification of core-periphery structure and contagion models. The closeness of exposure distributions is adequate to identify outlier institutions. The “core-periphery” structure, usually applied to banking network, is still valid with insurance companies. However this approach is not immune to size effect. This result contrasts with previous analyses where size was not accounted for. Contagion-based stress-tests are the best suited to capture institutions’ systemic fragility, emphasizing their importance as a supervisory tool.
The ‘to be or not to be’ of archaeological enquiry
Authors: d'Errico Francesco , Villa Paola , Degano Ilaria , Lucejko Jeanette , Colombini Maria Perla , Beaumont Peter
Published: July 2016

Pargeter and colleagues do not escape the dangers inherent in the exercise they embark on. The first is that of creating a straw man argument in which one exaggerates and misinterprets what was said in the article being criticised. The second is that of using your time to look at the speck of dust in your brother's eye instead of paying attention to the plank in your own. The third, if you are lucky enough to find a sympathetic journal, is to rehash the same criticism over and over in multiple articles, changing the tone from very moderate (Mitchell 2012) to more aggressive (Pargeter 2014), which inevitably pushes your opponents and any sensible reader to wonder about your motivations.
The Future of International Arbitration in Australia
Authors: Monichino Albert
Published: July 2016

The International Arbitration Act 1974 (Cth) is a Commonwealth Act that implements Australia’s obligations to enforce and recognise foreign arbitration agreements and arbitral awards under the Convention on the Recognition and Enforcement of Foreign Arbitral Awards 1959. The avowed purpose of the reforms was to position Australia as an attractive seat for arbitration in the Asia-Pacific region. Given the elapse of time since the amendments, it is opportune to reflect on how far Australia has come in that time, and the challenges and opportunities going forward. Undoubtedly, there has been a shift in the attitude of Australian courts towards greater judicial support and less judicial intervention in the arbitration process. Based on an extensive discussion of a particular dispute, TCL v Castel, the paper highlights that the High Court’s judgment confirms Australia is an arbitration-friendly jurisdiction. Had the decision gone the other way, it may have sounded the death knell for international arbitration in Australia.
A Conversation with His Honour Chief Magistrate Peter Lauritsen
Authors: Campbell Simon , Kordos Niko
Published: July 2016

Interview with the Chief Magistrate of the Magistrates’ Court of Victoria conducted on 10 July 2015 at the Magistrates’ Court of Victoria in Melbourne.
Foreword
Authors: Roxon Nicola
Published: July 2016

Foreword to Volume 5, Issue 1.
Cecilia Mangini
Authors: Missero Dalila
Published: July 2016

This essay offers a feminist reading of the work of Italian film director Cecilia Mangini. Drawing on an archaeological approach, it focuses on Mangini's experience as a woman in Italian cinema and her contribution to the realization of three movies—To Arms! We're Fascists! (codirected with Lino Del Fra and Lino Micciché, 1961–62), Stalin (directed with Lino Del Fra and Franco Fortini, 1962–63), and Being Women (1963–65)—all clear examples of the counterhegemonic cinema that Mangini developed in the fissures of mainstream, male-dominated practices. In her view, nonfiction film is a tool for cultural and political struggle, and it must affect the present in order to provide democratic access to knowledge. Following the Gramscian notion of the organic intellectual, Mangini has built a specific aesthetic and a personal approach to film direction, which aims to reach the broadest audience possible and, at the same time, to develop a coherent feminist militant discourse.
Layers of Film, Encrusted Images
Authors: Tralli Lucia
Published: July 2016

Cécile Fontaine's films do not tell stories in the traditional sense. Rather, they form spiraling involutions around an idea or a theme. Hers is a cinema of layers, encrustations, and material and plastic experimentation. It is a colorful and aquatic cinema that investigates—through stripping down and subsequent reconstruction—the material from which the images are made: the film strip itself. This essay investigates the poetics and the practice of Fontaine's found footage cinema, a cinema rigorously made without a movie camera, beginning with her first experiments with dry and wet techniques in the 1980s up to her more complex operations at the end of the 1990s. It is a cinema that, by fishing in the stream of abandoned images, reflects on the nature of the image, of memory and history, all rolled onto the vertical axis of the film.
“Feeling-Images”
Authors: Chiarini Alessandra
Published: July 2016

This essay investigates the ways in which Barbara Hammer’s film Nitrate Kisses (1992) traces stories about homosexuality throughout the twentieth century. Inspired both by the concept of “vertical cinema,” as theorized by Maya Deren, and by the historical-philosophical reflections of Michel Foucault and Walter Benjamin, Hammer realizes a montage process in Nitrate Kisses that resurrects a forgotten historical memory through the juxtaposition of archival materials and original images. It is a memory that is reappropriated through the film as an experiential, tactile, and emotional moment.
Regulation of mitotic spindle orientation: an integrated view
Authors: di Pietro Florencia , Echard Arnaud , Morin Xavier
Published: July 2016

Mitotic spindle orientation is essential for cell fate decisions, epithelial maintenance, and tissue morphogenesis. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral microtubules to position the spindle. Early studies identified the evolutionarily conserved Gαi/LGN/NuMA complex as a key regulator that polarizes cortical force generators. In recent years, a combination of genetics, biochemistry, modeling, and live imaging has contributed to decipher the mechanisms of spindle orientation. Here, we highlight the dynamic nature of the assembly of this complex and discuss the molecular regulation of its localization. Remarkably, a number of LGN‐independent mechanisms were described recently, whereas NuMA remains central in most pathways involved in recruiting force generators at the cell cortex. We also describe the emerging role of the actin cortex in spindle orientation and discuss how dynamic astral microtubule formation is involved. We further give an overview on instructive external signals that control spindle orientation in tissues. Finally, we discuss the influence of cell geometry and mechanical forces on spindle orientation.
Success after failure: the role of endometrial stem cells in recurrent miscarriage
Authors: Lucas Emma S , Dyer Nigel P , Fishwick Katherine , Ott Sascha , Brosens Jan J
Published: July 2016

Endometrial stem-like cells, including mesenchymal stem cells (MSCs) and epithelial progenitor cells, are essential for cyclic regeneration of the endometrium following menstrual shedding. Emerging evidence indicates that endometrial MSCs (eMSCs) constitute a dynamic population of cells that enables the endometrium to adapt in response to a failed pregnancy. Recurrent miscarriage is associated with relative depletion of endometrial eMSCs, which not only curtails the intrinsic ability of the endometrium to adapt to reproductive failure but also compromises endometrial decidualization, an obligatory transformation process for embryo implantation. These novel findings should pave the way for more effective screening of women at risk of pregnancy failure before conception.
Conceptos de la identidad cultural de estudiantes hispanounidenses
Authors: Monge Acuña Virginia
Published: July 2016

En este artículo se presenta una reflexión acerca del derecho a la identidad cultural; un concepto que en la actualidad genera consideraciones más allá de los contextos territoriales y temporales a la vez que enfatiza caracterizaciones particulares de diferenciación. Se discute el concepto de identidad cultural como derecho de los estudiantes hispanounidenses y la estrecha relación de la lengua de herencia con esta.  Además, el artículo  presenta los conceptos de reconstrucción de la dignidad y la pertenencia referentes a la identidad cultural, provenientes directamente de las voces de estudiantes hispanounidenses de la escuela secundaria. Por tanto, se concluye que en este proceso, el fortalecimiento de la lengua de herencia posee un rol indispensable.
Alberto Patishtán Gómez: Radiografía de un indulto tardío
Authors: Muñoz Vargas Osvaldo Antonio
Published: July 2016

El autor muestra el insólito caso de Alberto Patishtán Gómez (Chiapas, México 2000), en cual presenta cronológicamente los hechos que se llevaron a cabo en el paraje Las Lagunas de Las Limas, Municipio de Simojovel.  La importancia del caso se da al sobreestimar el relieve de violaciones de proceso en derechos humanos por sobre el trasfondo del derecho penal. En este caso específico, el autor pretende analizarlo desde una perspectiva puramente política, dejando de lado cualquier matiz antropológico de fondo en el cual, ante una relectura, se podría inferir fácilmente que hubo discriminación étnica
Identification of Patients at Risk of Stroke From Atrial Fibrillation
Authors: Fohtung Raymond B ,   Washington University School of Medicine, St Louis, MO, Rich Michael W ,   Washington University School of Medicine, St Louis, MO
Published: July 2016

Atrial fibrillation (AF) is a highly prevalent arrhythmia associated with a fivefold increase in the risk of stroke. However, this risk is not homogeneous and varies considerably depending on the presence of several demographic and clinical factors. Independent risk factors for stroke in patients with AF include age ≥65 years, female sex, congestive heart failure, prior stroke or transient ischemic attack, hypertension, diabetes mellitus and vascular disease. Based on these indicators, risk stratification schemes to identify patients at low-, moderate-, and high-risk for stroke have been developed and validated. The CHADS2and CHA2DS2-VASc schemes are widely used and have good predictive accuracy for stroke. Current guidelines recommend the CHA2DS2-VASc scheme, in part because it more accurately identifies patients at truly low risk for stroke who do not require antithrombotic therapy. This article provides an overview of risk factors for stroke in patients with AF, including discussion of the CHADS2and CHA2DS2-VASc schemes.
Reapropiación del conocimiento y descolonización: el acceso abierto como proceso de acción política del sur
Authors: Aguado-López Eduardo , Vargas Arbeláez Esther Juliana
Published: July 2016

En este artículo se analiza la idea de que el modelo de comunicación científica dominante entraña una forma de colonialidad del saber, en los términos del grupo de científicossociales latinoamericanos, de finales del siglo pasado,  conformado por A. Escobar, E. Dussel, S. Castro-Gómez, entre otros. Esta forma de colonialidad del saber se puede subvertir con el fortalecimiento de la práctica de circulación del conocimiento denominada acceso abierto (AA). El estudio sigue un proceder analítico, mediante la descripción del panorama de la producción científica de América Latina y el Caribe. Eneste panorama, se aprecia el problema que representa la evaluación del quehacer científico latinoamericano a partir de ciertos estándares, y su consecuente subrrepresentación en bases de datos, como el Journal Citation Report (JCR) y elScientific Journal Ranking (SJR). Con esta descripción, se revisa la presencia latinoamericana de las ciencias sociales en el acervo que alberga SCIELO y Redalyc. Este estado de cosas se analiza, posteriormente, a la luz de un aparato teórico construido entorno a dos categorías: dispositivo, en la versión de Agamben, en el artículo del mismo nombre, y descolonialidad del saber. Estos dos elementos teóricos aportan a la comprensión de un horizonte político del camino del acceso abierto en América Latina y el Caribe, ya que —esta es la conclusión a la que apunta el texto— esta práctica se perfila en nuestra región como una apuesta política para una descolonización y reapropiación delconocimiento, en el sentido de la filosofía política italiana contemporánea. Lo anterior porque permite el acceso a los productos de investigación financiados públicamente, el“retorno” de la producción científica y, especialmente, la reconsideración de formas de valoración de la ciencia.
Centroamérica en las globalizaciones (siglo XVI-XXI)
Authors: Acuña Víctor Hugo
Published: July 2016

Este ensayo intenta acercar la experiencia histórica centroamericana a las corrientes actuales de la historia y las ciencias sociales a nivel internacional, las cuales han experimentado lo que se ha denominado un giro global. Se propone la hipótesis que Centroamérica ha participado en las distintas fases de la globalización en su condición de región geoestratégica en el conjunto del planeta, como istmo entre los dos océanos más importantes del planeta y como puente entre la América del Norte y la América del Sur. Desde el siglo XVI, cuando se inserta en los procesos de global- ización, la función de istmo ha prevalecido. No obstante, en la fase actual de la global- ización su función de puente ha adquirido gran relevancia. Complementariamente, la región se inserta en los procesos de globalización en función de su condición de península subtropical de Norteamérica. El ensayo explora los grados de conciencia de globalidad que han existido en la región desde finales del siglo XVI, muestra el triunfo del nacionalismo metodológico a fines del siglo XIX y propone repensar la historia del istmo a la luz de ese giro global en las ciencias sociales.
Diversiones públicas y Estado en Nicaragua 1877-1936
Authors: Urbina Gaitán Chester
Published: July 2016

El control del Estado nicaragüense de las diversiones públicas y del tiempo libre durante el periodo 1877-1908 giró alrededor del respeto al tiempo laboral y la no participación en lugares de juego de algunos sectores sociales, entre ellos los menores de edad. Para el periodo de 1909 a 1936 ademásde mantenerse estas disposiciones se tiene que las diversiones públicas fueron usadas para mantener la ocupación estadounidense, siendo el beisbol la actividad más promocionada.
Monstruos que gobiernan, animales que devoran. La crítica al liberalismo desde la zoología política de Costa Rica (1870-1900)
Authors: Arias Mora Dennis
Published: July 2016

Este artículo estudia las metáforas animales en el pensamiento crítico frente al liberalismo costarricense, a partir del caso de José María Figueroa (1820-1900) y su oposición al régimen de Tomás Guardia (1870-1882). Se propone que, en su sátira gráfica y textual, el autor conjugó su biografía como joven dibujante, “vagabundo” y conspirador, con posteriores saberes de carácter biopolítico, para elaborar un método definido aquí como abyecto que, oculto por la limitación autoritaria de la deliberación pública, develó lo monstruoso e infame en la arbitrariedad, corrupción, metafórica y épica del poder. Documentos de archivo, prensa, mensajes presidenciales y cuadernos personales permiten concluir que esta zoología política es la manifestación temprana de un lenguaje que no desaparece con la democracia.
"Culturas bananeras: producción, consumo y transformaciones socioambientales", de John Soluri
Authors: León Araya Andrés
Published: July 2016

Andrés León Araya. Costarricense, doctor en antropología por la Universidad de la Ciudad de Nueva York. Actualmente trabajo como profesor en las escuelas de Ciencias Políticas y Antropología de la Universidad de Costa Rica, así como investiga- dor en el Centro de Investigaciones y Estudios Políticos (CIEP) de la misma institución. Autor del libro Desarrollo geográ co desigual en Costa Rica: el ajuste estructural visto desde la región Huetar Norte (1985-2005) (2015).
A new Roman sarcophagus from Komárom-Esztergom county
Authors: Kovács Péter
Published: July 2016

In the Museum of Tata there is an unpublished Roman sarcophagus. Because of the hardly legible inscription it has been unpublished for decades. The sarcophagus was erected by a former beneficiarius to his wife and daughter. The structure of the inscription is very unusual with two clauses because the veteran had bought the sarcophagus when his wife was still alive, later he together with his children buried them both into the sarcophagus. Because of the damaged part two restoration possibilities have been proposed. The sarcophagus was made in a local workshop of Brigetio. The inscription can be dated to the middle of the 3rd century but before the reform of Gallienus in the 260s, as still a senatorial legatus legionis was mentioned.
Association of Campylobacter jejuni ssp. jejuni chemotaxis receptor genes with multilocus sequence types and source of isolation
Authors: Mund Norah Lynn-Anne , Masanta Wycliffe Omurwa , Goldschmidt Anne-Marie , Lugert Raimond , Groß Uwe , Zautner Andreas E.
Published: July 2016

Campylobacter jejuni’s flagellar locomotion is controlled by eleven chemoreceptors. Assessment of the distribution of the relevant chemoreceptor genes in the C. jejuni genomes deposited in the National Center for Biotechnology Information (NCBI) database led to the identification of two previously unknown tlp genes and a tlp5 pseudogene. These two chemoreceptor genes share the same locus in the C. jejuni genome with tlp4 and tlp11, but the gene region encoding the periplasmic ligand binding domain differs significantly from other chemoreceptor genes. Hence, they were named tlp12 and tlp13.

Consequently, it was of interest to study their distribution in C. jejuni subpopulations of different clonality, and their cooccurrence with the eleven previously reported chemoreceptor genes. Therefore, the presence of all tlp genes was detected by polymerase chain reaction (PCR) in 292 multilocus sequence typing (MLST)-typed C. jejuni isolates from different hosts.

The findings show interesting trends: Tlp4, tlp11, tlp12, and tlp13 appeared to be mutually exclusive and cooccur in a minor subset of isolates. Tlp4 was found to be present in only 33.56% of all tested isolates and was significantly less often detected in turkey isolates. Tlp11 was tested positive in only 17.8% of the isolates, while tlp12 was detected in 29.5% of all isolates, and tlp13 was found to be present in 38.7%.
A C-terminal coiled-coil region of CagL is responsible for Helicobacter pylori-induced IL-8 expression
Authors: Wiedemann Tobias , Hofbaur Stefan , Loell Eva , Rieder Gabriele
Published: July 2016

Interleukin-8 (IL-8) is a potent neutrophil-activating chemokine which triggers the infiltration and migration of neutrophils into areas of bacterial infection. Helicobacter pylori-infected patient studies as well as animal models have revealed that H. pylori type I strains carrying an intact cytotoxin-associated gene pathogenicity island (cag-PAI) with a functional type IV secretion system (T4SS) induce IL-8 expression and secretion in gastric mucosa. This gastric mucosal IL-8 expression correlates with severe histological changes due to H. pylori infection.

In the present study, we explored a new recognition pattern on the bacterial adhesion protein CagL inducing IL-8 expression in H. pylori-infected host cells. To analyze the secreted IL-8 concentration, we performed IL-8 enzyme-linked immunosorbent assay (ELISA). To investigate the H. pylori-induced IL-8 expression on the transcriptional level, we transiently transfected gastric epithelial cells (AGS) with a human IL-8 luciferase reporter construct.

The results of this study demonstrate that specifically the C-terminal coiled-coil region of the H. pylori CagL protein, a protein described to be located on the tip of the T4SS-pilus, is responsible for several in vitro observations: 1) H. pylori-induced IL-8 secretion via the transforming growth factor (TGF)-α activated epidermal growth factor-receptor (EGF-R) signaling pathway; 2) H. pylori-induced elongation of the cells, a typical CagA-induced phenotype; and 3) the bridging of the T4SS to its human target cells. This novel bacterial-host recognition sequence allows a new insight into how H. pylori induces the inflammatory response in gastric epithelial cells and facilitates the development of precancerous conditions.
New records and an update of the distribution of Sibon annulatus (Colubridae: Dipsadinae: Dipsadini) for Colombia
Authors: Meneses-Pelayo Elson , Echavarría-Rentería Juan David , Bayona-Serrano Jonard David , Caicedo-Portilla José Rances , Rengifo-Mosquera Jhon Tailor
Published: July 2016

We revised and identified preserved specimens of Sibon annulatus (Günther, 1872)to present an update of its geographical distribution in Colombia. We include three new records of this species, which expand its distribution within Colombia to the departments of Chocó and Santander.
First record of Amatitlania nigrofasciata (Günther, 1867) (Cichliformes: Cichlidae) as introduced species in natural freshwaters of Colombia
Authors: Herrera-R Guido A. , Murcia-Castillo Miguel A. , Prada-Pedreros Saúl
Published: July 2016

Amatitlania nigrofasciata is a small fresh­water fish species native to Central America. Is a popular ornamental fish that has been traded and cultivated for the aquarium industry, introduced into temperate and tropical regions across the world. Two specimens of A. nigrofasciata were collected from two small creeks draining into the Guavio River, upper Meta River in Mambita, Ubalá, Cundinamarca, Colombia in the Piedmont Orinoco ecoregion. This is the first record of A. nigrofasciata in natural freshwaters of Colombia and the Orinoco River basin. Diagnostic characters of species and updated distribution at country level are provided.
Interprofessional education (IPE) between Medical and Dietetic students: Prescribing Medical Nutrition Therapy?
Authors: Cherian Anna , Gupta Suman , Habash Diane , Nahikian-Nelms Marcia , Pfeil Sheryl
Published: July 2016

This article was migrated. The article was not marked as recommended. Introduction : Interprofessional education (IPE) is a collaborative learning process between health professionals to improve healthcare outcomes. Limited data exists on IPE specifically between medical students (MS) and dietetic students (DS). Our study evaluated a two hour didactic and experiential Medical Nutritional Therapy (MNT) session for MS, facilitated by dietetics faculty and DS. Methods: Dietetics faculty provided a didactic training on nutritional risk assessment and MNT. Then, DS worked with groups of MS to alter sample meals using MNT guidelines. Psychosocial and economic challenges were addressed. MS completed pre and post-session surveys and DS gave reflective feedback. Results: Significant change in pre to post survey scores occurred for every question (p<0.006). MS reported increased confidence for altering meals for MNT, suggesting healthy food solutions, recognizing nutrition risk, and understanding the role of dietitians. DS felt their role on healthcare teams was recognized. Conclusions: This novel study was the first of its kind to assess an IPE session solely between MS and DS, underscoring the use of food as medicine. MS learned about specific MNTs, making appropriate food alterations, and responding to psychosocial/economic challenges. Future studies should assess longitudinal impact on MS and their incorporation of Registered Dietitians in future practice.
Spray adjuvant characteristics affecting agricultural spraying drift
Authors: OLIVEIRA RONE B. DE , ANTUNIASSI ULISSES R. , GANDOLFO MARCO A.
Published: July 2016

This study defined the main adjuvant characteristics that may influence or help to understand drift formation process in the agricultural spraying. It was evaluated 33 aqueous solutions from combinations of various adjuvants and concentrations. Then, drifting was quantified by means of wind tunnel; and variables such as percentage of droplets smaller than 50 μm (V50), 100 μm (V100), diameter of mean volume (DMV), droplet diameter composing 10% of the sprayed volume (DV0.1), viscosity, density and surface tension. Assays were performed in triplicate, using Teejet XR8003 flat fan nozzles at 200 kPa (medium size droplets). Spray solutions were stained with Brilliant Blue Dye at 0.6% (m/ v). DMV, V100, viscosity cause most influence on drift hazardous. Adjuvant characteristics and respective methods of evaluation have applicability in drift risk by agricultural spray adjuvants.
Color change and quality response of ‘lane late’ orange submitted to degreening process
Authors: MACHADO FRANCISCA L. DE C. , CAJAZEIRA JOÃO P. , COSTA JOSÉ M. C. DA
Published: July 2016

This study aimed at evaluating the effects of ethylene on peel color and compositional changes in ‘Lane late’ orange stored under refrigerated and ambient conditions. Physiologically mature, but green-peeled, oranges were exposed to ethylene gas under room temperature and high relative humidity for 24 hours. Storage chamber was ventilated with fresh air after 12 hours to mitigate consequences derived from fruit respiration. Both nondestructive analysis, such as peel color (hue angle, chromaticity, and brightness) and weight loss, and destructive ones (soluble solids, titratable acidity, pH, soluble solids to acidity ratio, and puncture force) were performed upon harvest, after degreening, and every three days during eighteen days in storage. Experiment was carried out using an entirely randomized design with thirty replications for nondestructive and four replications for destructive analyses, in a split plot scheme. Exposure to ethylene ensured a golden yellow peel for both fruit stored under ambient and refrigerated conditions. High relative humidity, associated with low temperature prevented fruit from losing moisture. Fruit exposure to ethylene did not affect weight loss, soluble solids, titratable acidity, pH, soluble solids, acidity ratio, or puncture force.
Financial losses in pork supply chain: a study of the pre-slaughter handling impacts
Authors: REIS JOÃO G. M. DOS , MACHADO SIVANILZA T. , SANTOS RODRIGO C. , NÄÄS IRENILZA DE A. , OLIVEIRA RONE V.
Published: July 2016

Brazil is amongst the world’s largest swine producers. However, its competitiveness has been vulnerable due to a lack of cooperation between the supply chain players. This condition makes the financial losses to be evaluated taking into account only an individual node, and most of the time, these damages are imputed by swine breeders. Living weight losses occur between the farm to slaughterhouses, and the main cause of these losses is the pre-slaughter handling, especially during animal transportation. In this research, we analyzed the pre-slaughter handling in a swine farm in Brasilândia, MS, Brazil. Analyzed data were provided by five slaughterhouses (farm clients) from the studied region, in which it was considered living weight losses, carcass bruising, animal injury, and death rate. The results indicated that total financial losses represent 160 thousand dollars per year, when taking into account the supply chain management.
Estimation methods of reference evapotranspiration (ETo) for Uberlândia -MG
Authors: LACERDA ZILDA C. DE , TURCO JOSÉ E. P.
Published: July 2016

One approach to verify the adequacy of estimation methods of reference evapotranspiration is the comparison with the Penman-Monteith method, recommended by the United Nations of Food and Agriculture Organization - FAO, as the standard method for estimating ET0. This study aimed to compare methods for estimating ET0, Makkink (MK), Hargreaves (HG) and Solar Radiation (RS), with Penman-Monteith (PM). For this purpose, we used daily data of global solar radiation, air temperature, relative humidity and wind speed for the year 2010, obtained through the automatic meteorological station, with latitude 18° 91' 66" S, longitude 48° 25' 05" W and altitude of 869m, at the National Institute of Meteorology situated in the Campus of Federal University of Uberlandia - MG, Brazil. Analysis of results for the period were carried out in daily basis, using regression analysis and considering the linear model y = ax, where the dependent variable was the method of Penman-Monteith and the independent, the estimation of ET0 by evaluated methods. Methodology was used to check the influence of standard deviation of daily ET0 in comparison of methods. The evaluation indicated that methods of Solar Radiation and Penman-Monteith cannot be compared, yet the method of Hargreaves indicates the most efficient adjustment to estimate ETo.
Effect of companion ion on nitrate displacement through transport parameters analysis
Authors: SILVA LÍVIA P. DA , MIRANDA JARBAS H. DE , OLIVEIRA LUCIANO A. , JOSÉ JEFFERSON V.
Published: July 2016

Nitrate is the main form of nitrogen associated with water contamination; the high mobility of this species in soil justifies the concern regarding nitrogen management in agricultural soils. Therefore, the objective of this research was to assess the effect of companion cation on nitrate displacement, by analyzing nitrate transport parameters through Breakthrough Curves (BTCs) and their settings made by numerical model (STANMOD). The experiment was carried out in the Soil and Water Quality Laboratory of the Department of Biosystems Engineering, "Luiz de Queiroz" College of Agriculture in Piracicaba (SP), Brazil. It was performed using saturated soil columns in steady-state flow condition, in which two different sources of inorganic nitrate Ca(NO3)2 and NH4NO3 were applied at a concentration of 50 mg L-1 NO3-. Each column was filled with either a Red-Yellow Oxisol (S1) or an Alfisol (S2). Results are indicative that the companion ion had no effect on nitrate displacement. However, nitrate transport was influenced by soil texture, particle aggregation, solution speed in soil and organic matter presence. Nitrate mobility was higher in the Alfisol (S2).
Technology for sugarcane agroindustry waste reuse as granulated organomineral fertilizer
Authors: GURGEL MARCÍLIO N. DO A. , CORREA SIMONE T. R. , DOURADO NETO DURVAL , PAULA JÚNIOR DURVAL R. DE
Published: July 2016

Aiming to evaluate the use of sugarcane industry waste such as byproducts from vinasse concentration process, it was assessed the organomineral fertilizer BIOFOM (concentrated vinasse, filter cake, boiler ash, soot from chimneys and supplemented with mineral fertilizers). The study included characterization and agronomic potential analysis of a test plant (corn), by noting the differences between mineral fertilizers and BIOFOM fertilization until 45 days after sowing. The technology traditionally used to produce BIOFOM was based on vinasse evaporation with high heat transfer coefficients. It was observed that the technology, which can be formulated according to the needs of any crop, could be used in many cases as mineral fertilizer. Therefore, the use of this organomineral fertilizer reduces waste generation of sugarcane industry.
Application of artificial neural networks as an alternative to volumetric water balance in drip irrigation management in watermelon crop
Authors: ROCHA NETO ODÍLIO C. DA , TEIXEIRA ADUNIAS DOS S. , BRAGA ARTHUR P. DE S. , SANTOS CLEMILSON C. DOS , LEÃO RAIMUNDO A. DE O.
Published: July 2016

Precision irrigation seeks to establish strategies which achieve an efficient ratio between the volume of water used (reduction in input) and the productivity obtained (increase in production). There are several studies in the literature on strategies for achieving this efficiency, such as those dealing with the method of volumetric water balance (VWB). However, it is also of great practical and economic interest to set up versatile implementations of irrigation strategies that: (i) maintain the performance obtained with other implementations, (ii) rely on few computational resources, (iii) adapt well to field conditions, and (iv) allow easy modification of the irrigation strategy. In this study, such characteristics are achieved when using an Artificial Neural Network (ANN) to determine the period of irrigation for a watermelon crop in the Irrigation Perimeter of the Lower Acaraú, in the state of Ceará, Brazil. The Volumetric Water Balance was taken as the standard for comparing the management carried out with the proposed implementation of ANN. The statistical analysis demonstrates the effectiveness of the proposed management, which is able to replace VWB as a strategy in automation.
Desempenho agronômico de Mentha aquatica cultivada em sistemas alagados construídos sob diferentes taxas de aplicação orgânica
Authors: AVELAR FABIANA F. , MATOS ANTONIO T. DE , LEITE JUNIOR ALVIMAR R. , PORTES MATHEUS R. , GUALHANO DANIEL S.
Published: July 2016

Em vista da escassez de informações sobre o comportamento da espécie Mentha aquatica quando cultivada sob condições de alagamento e altas concentrações orgânicas, objetivou--se avaliar o efeito de diferentes taxas de carregamento orgânico (TCOs) sobre a produtividade e o estado nutricional da espécie cultivada em sistemas alagados construídos (SACs) de escoamento horizontal subsuperficial no tratamento de efluente primário de esgoto sanitário. Dois SACs de 24,0 m x 1,0 m x 0,35 m, preenchidos com brita “zero” até a altura de 0,20 m, foram cultivados com a espécie. O experimento foi realizado em duas etapas: na primeira, avaliaram-se as TCOs de 40,35 kg ha-1 d-1 e 53,80 kg ha-1 d-1 de DBO5; na segunda etapa, as TCOs de 79,66 kg ha-1 d-1 e 160,35 kg ha-1 d-1 de DBO5. Ao final de cada etapa, amostras da parte aérea das plantas foram coletadas para quantificação de rendimento de matéria seca e análises dos teores foliares de nitrogênio, fósforo, potássio e sódio. Apesar de cultivada sob condições de alagamento, a espécie apresentou elevada produtividade. O aumento na TCO aplicada aos sistemas favoreceu a produção de matéria seca e o aumento na concentração foliar de nitrogênio, potássio e sódio.
Energetic sustainability of three arabica coffee growing systems used by family farming units in Espírito Santo state
Authors: Muner Lúcio H. de , Masera Omar , Fornazier Maurício J. , Souza Cássio V. de , Loreto Maria Das D. S. de
Published: July 2016

Three growing systems of Arabica coffee were evaluated under the energy perspective, in the state of Espírito Santo in Brazil. The systems are conventional cultivation (CC), cultivation with good agricultural practices (CGP) and organic farming (OF). It was made a comparison of the energy flows within these three systems to show sustainable levels of each one based on production average data of several family-farming units. Therefore, we analyzed crop yield, total energy efficiency reverse (TEER), energy efficiency of ripe coffee (EERC) and non-renewable energy efficiency (NREE). OF system had values for TEER, EERC and NREE of 3.3 4.7 and 7.9 respectively. Yet CC showed values of 1.8, 1.9 and 1.6 for TEER, EERC and NREE respectively. Furthermore, CGP presented values for TEER, EERC and NREE of 0.7, 1.3 and 1.4 respectively. The highest yield was observed in CGP, reaching an amount of 1794 kg ha-1(17,455 MJ); however, this system expends more energy than it converts. Thus, over those points, OF is the most sustainable system.