bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast-conserving surgery versus mastectomy for older women with triple-negative breast cancer: population-based study
Authors: Mburu Waruiru , Kulasingam Shalini , Hodges James S , Virnig Beth A
Published: July 2022

Purpose:
To assess whether the poor prognosis of triple-negative breast cancer (TNBC) necessitates a more aggressive surgical approach.
Methods:
We examined the association of: breast-conserving surgery (BCS); BCS plus radiotherapy; mastectomy; and mastectomy plus radiotherapy with overall and breast cancer-specific survival of stage I–III TNBC patients aged 66 years and older. We used unweighted and inverse probability of treatment weighted Cox proportional hazards regression and the Fine and Gray sub-distribution model.
Results:
Among 4333 women, individuals who were selected for BCS, mastectomy or mastectomy plus radiotherapy had lower adjusted overall and breast cancer-specific survival compared with women who had BCS plus radiotherapy.
Conclusion:
In this population-based study, women with TNBC treated with BCS plus radiotherapy have a better prognosis than those treated with BCS, mastectomy or mastectomy plus radiotherapy. Given the poor prognosis of TNBC and selection bias inherent in observational studies, these findings should be confirmed in further studies such as randomized clinical trials.
Trombocitopenia como efecto secundario por la administración de heparinas en los pacientes de COVID-19. Una revisión sistemática
Authors: Badillo-Samapayo Jessica , Aguilar-Castro Jesús
Published: July 2022

Introducción. En la actualidad existen algunas publicaciones que describen alteraciones de la coagulación y complicaciones trombóticas arteriales y venosas principalmente en pacientes ingresados en unidades de cuidados intensivos por COVID-19. Sin embargo, no se ha publicado una revisión sistemática sobre dicha alteración. Objetivo. Presentar una síntesis del conocimiento sobre la frecuencia de la trombocitopenia como efecto secundario por la administración de heparinas en pacientes por COVID-19. Métodos. Se llevó a cabo una búsqueda en las plataformas de PubMed, SCOPUS, Biblioteca Cochrane, LILACS, Web of Science y literatura gris como TESIUNAM desde el 10 diciembre de 2021 hasta el 13 de enero de 2022, para identificar estudios que reportaran casos con HIT con pruebas confirmatorias que demuestren la activación plaquetaria de los Abs anti-PF4 / H en presencia de heparina, se utilizaron las siguientes palabras clave y estrategia “COVID-19" OR "SARS-CoV-2” OR "Coronavirus Infections” AND "low-molecular-weight heparin” OR “LMWH” OR “heparin” AND “unfractionated heparin" OR "UFH" AND “Thrombocytopenia” OR “TIH” OR “anti-H/PF4” OR “factor 4-heparin” OR “HPIA”. Resultados. Se identificaron 861 artículos, se revisaron 26 artículos de texto completo, se realizó un análisis cualitativo de 12 estudios que cumplían con los criterios de elegibilidad. Se encontró dentro de cuatro estudios de cohorte una incidencia de trombocitopenia de 0.16% a 8%. De los 12 casos clínicos, con un promedio de edad de 61.3 años. Al 50% de los pacientes de las cohortes confirmados con trombocitopenia se le administró Heparina fraccionada y a los pacientes reportados en los casos clínicos se le administró al 43%. Conclusión. Los resultados sugieren que el efecto secundario de la administración de heparinas podría aumentarse en personas mayores en estado crítico que reciben heparina fraccionada en dosis terapéuticas, sin embargo, es necesario realizar más estudios para confirmar los hallazgos. Palabras clave: COVID-19, SARS-CoV-2, heparina, Trombocitopenia
Students Perception on Online Learning During a Pandemic at SMAN 1 Lembah Melintang Pasaman Barat
Authors: Yani Ranti Fitri , Sani Riny Dwitya , Sevrika Hevriani
Published: July 2022

ABSTRAK Penelitian ini dilatarbelakangi oleh pandemi Covid-19 yang terjadi di Indonesia sejak Desember 2019. Peneliti tertarik untuk mengetahui persepsi siswa terhadap online learning pada masa pandemi Covid-19. Tujuan penelitian ini adalah untuk mengetahui persepsi siswa terhadap online learning pada masa pandemi Covid-19. Penelitian ini merupakan penelitian kualitatif dengan metode deskriptif yang bertujuan untuk mendeskripsikan dan mengetahui persepsi siswa terhadap online learning pada masa pandemi Covid- 19. Penelitian ini menggunakan angket dan wawancara sebagai instrument dalam penelitian ini. Jumlah sampel penelitian adalah sebanyak 60 siswa di SMAN 1 Lembah Melintang Pasaman Barat. Pengumpulan data dengan cara membagikan angket kepada 60 siswa dan melakukan interview dengan 7 siswa. Hasil dari penelitian ini menunjukkan bahwa persepsi siswa SMAN 1 Lembah Melintang terhadap online learning adalah tidak efektif pada masa pandemi covid-19.Kata Kunci : Students Perception, Online Learning, Pandemic Covid-19
Perancangan Sistem Informasi Penjadwalan Laboratorium Pendidikan Informatika Universitas PGRI Sumatera Barat
Authors: Giawa Erwin Sofyan Putri , Mary Thomson , Samudra Ami Anggraini
Published: July 2022

The preparation and writing of the practicum lecture schedule in the Informatics Education computer laboratory has not been optimal. In addition, the laboratory loan process has not been efficient in terms of time, because lecturers and students have to contact and come directly to the laboratory. The purpose of this study was to design and test a laboratory scheduling information system for the informatics education study program at Universitas PGRI Sumatera Barat using the Software Development Life Cycle (SDLC) method. This research resulted in an information system that can help labor technicians, lecturers, students and related stakeholders. The results of beta testing research on expert validation obtained an average validation of 87.4% with very good information and the user assessment questionnaire obtained an average value of 89.8% with very good information.
Perancangan Sistem Informasi Jasa Laundry berbasis Android Pada Bio Clean Laundry
Authors: Ardhi Muhammad , Mary Thomson , Samudra Ami Anggraini
Published: July 2022

Usually the recording of transactions in Bio Clean Laundry is done by writing transactions in a book that has been provided, so that it often causes errors in recording the transaction notes and the results of washing transactions. In addition, there are often discrepancies in the data resulting from transactions so that the business suffers losses. Based on these problems, an Android-Based Laundry Service information system was designed at Bio Clean Laundry using the Unified Modeling Language (UML) modeling language and getting to know programming languages using Block Programming, and the system development life cycle (SDLC) method where this method has planning stages, analysis phase, design phase, implementation phase, testing phase, and maintenance phase. Testing of this information system is done by using blackbox and whitebox methods. Based on testing with the blackbox method, 4 menus were tested with the expected results as many as 12 procedures and 26 results by obtaining a valid percentage of success results. This indicates that all the information system testing scenarios are as expected so that officers can easily record customer data and sales transactions, so this information system can function properly.
Sistem Informasi Manajemen Data Surat Berbasis Web di Dinas Penanaman Modal Dan Pelayanan Terpadu Satu Pintu Provinsi Sumatera Barat
Authors: Rijal Muhammad , Mary Thomson , Irsyadunas Irsyadunas
Published: July 2022

This research intends to create a web-based mail data management information system at Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu Provinsi Sumatera Barat which can facilitate archivists in managing correspondence to speed up correspondence processing, make it easier for archivists to find evidence of correspondence, can store, change, print correspondence data and reduce the accumulation of archives in the workspace in the Secretariat. This research method is carried out by collecting data through internships, observations, and interviews. The method used in developing this system uses the SDLC concept. At the analysis stage, the system modeling uses the Unified Modeling Language (UML) as a design tool. The implementation process is carried out using the MySQL database and the PHP programming language. The process of testing this system is carried out using the Black Box testing method. The results of the trial of the designed system have been in accordance with the needs expected by the agency. This research has produced a mail data management information system at Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu Provinsi Sumatera Barat
Case study on Experimental study of Oil Spill Clean-up Methods for More Effective Handling of Future Accidents
Authors: Nayak Debasish , Pattanaik Surajit , Hota Shibani
Published: July 2022

Abstract: Petroleum (oil) is an essential natural resource for modern industrial society; it is used to produce energy and materials, which serve a variety of manufacturing, industrial and consumer needs. However, extensive oil extraction, transport and use have resulted in many accidental oil spills. USA Today reported in 2010 that the number of spills in the US has more than quadrupled over the previous decade. Oil spills pose hazards to both humans and wildlife, and adversely affect local ecosystems. It is therefore important for governments, industry and emergency managers to understand, appreciate, and hopefully improve strategies for oil cleanup. It is essential to review both the strategies that have worked and those that have not, so that optimal methods for handling such catastrophic events can be clearly identified. This report will serve as a case study analysis to assess best- and worst-case oil cleanup methods; by categorizing previous events based on gravity of the spill, cleanup success levels, length of time for remediation, and type of affected environment, more effective strategies can be developed for Evaluating and managing cleanup efforts. This includes more rapid oil spill cleanup with minimal impact on the local environment. The case studies reveal that human error is the single most important factor correlating with risk of oil spills; therefore, more effort should be spent towards prevention than on the development of new technologies for cleanup response. However, when the inevitable oil spill occurs, bioremediation and dispersant application are concluded to be the preferred methods.
BAĞLAMADA KULLANILAN BURGU VE BURGULUK ÇEŞİTLERİNE YÖNELİK TESPİTLER
Authors: GÖKTAŞ Uğur , DURSUN Doğukan
Published: July 2022

Bağlamada akort yapmayı sağlayan burgu ve burguluk kısımları geçmişten günümüze geleneksel yöntemlerle yapılmaktadır. Buna karşın farklı çalgılardan esinlenilerek yapılan burgu ve burguluk çeşitlerine de rastlanmaktadır. Ayrıca bağlamanın otantik görünümüne bağlı kalarak yapılan ve akordun daha uzun süreli korunmasının amaçlandığı yeni özgün burgu ve burguluk çeşitlerinin üretildiği görülmektedir. Araştırma durum tespiti yapmaya yönelik olup betimsel bir özelliğe sahiptir. Araştırma sürecinde dijital ve yazılı kaynaklar taranarak konuya yönelik bilgiler elde edilmeye çalışılmıştır. Daha sonra bağlama yapımcılarının ve icracılarının bağlamadaki burgu ve burguluk çeşitlerine yönelik tercihleri, kişisel görüşme ve anket tekniklerinin uygulanmasıyla nicel ve nitel bulgularla birlikte değerlendirilmeye çalışılmıştır. Araştırma sonuçlarından bazıları sıralanacak olursa; geleneksel bağlama burgu ve burguluk çeşitlerinin diğer burgu ve burguluk çeşitlerine göre daha yaygın bir şekilde kullanıldığı, gitar/mandolin burgu ve burguluk çeşitlerinin geleneksel burgu ve burguluk çeşitlerine göre daha karmaşık, maliyetli ve ağır olduğu, gitar/mandolin burgu ve burguluk çeşitlerinde tel takma/sökme işleminin diğer burgu ve burguluk çeşitlerine göre daha karmaşık olduğu ancak daha hassas akort yapılabildiği, bağlama akordunun daha hassas ayarlanması ve uzun süreli korunmasına yönelik yeni burgu çalışmalarının olduğu akla ilk gelenlerden bazılarıdır.
Estado e sociedade na construção de capacidades para fortalecer práticas de governança territorial
Authors: Dallabrida Valdir Roque , Büttenbender Pedro Luís , Covas António Manuel Alhinho , Covas Maria das Mercês Cabrita de Mendonça , Costamagna Pablo , Menezes Elaine Cristina de Oliveira
Published: July 2022

Parte-se do entendimento de que processos de articulação territorial, com vistas à prospecção do futuro desejado territorialmente, exigem práticas de governança colaborativa, horizontal e democrática, envolvendo agentes estatais e representações dos setores sociais, produtivo-empresarial e universitários. Ambientes de alta complexidade, aliados à transformação digital contemporânea, alteraram significativamente a agenda dos territórios, permitindo questionar as competências e capacidades dos atores territoriais para atuar em processos de articulação territorial. Isso ratifica a visão de que essa complexidade sistêmica seja assimilada por intermédio de um hibridismo metodológico, multirreferencial, que contemple processos de coprodução e pesquisa-ação. O objetivo deste artigo é gerar aportes teórico-metodológicos para abordar os desafios postos ao Estado e à sociedade na construção de capacidades para as práticas de governança territorial. O texto está estruturado na forma de um ensaio teórico, referenciado na produção acadêmica latino-americana sobre o tema.
Menyingkap Makna Objek Pendidikan dalam Istilah Al-Ahl/الأهل, Al-‘Asyirah/العشيرة, Al-Aqrab/الأقرب
Authors: Harahap Musaddad , Hitami Munzir , Anwar Abu
Published: July 2022

Masalah dalam penelitian ini adalah pentingnya memahami hakikat objek pendidikan perspektif pendidikan Islam. Secara umum objek pendidikan sering dipahami hanya sekedar manusia yang membutuhkan pembelajaran. Namun dalam pendidikan Islam, objek pendidikan tidak hanya sekedar manusia secara individual, tetapi melebihi dari itu. Manusia sebagai objek pendidikan memiliki dimensi yang sangat luas. Pendidikan Islam telah mengisyaratkan hal itu dalam sumber utamanya yaitu Al-Qur’an dan Sunaah Nabi Muhammad SAW. Untuk menjawab masalah penelitian ini, maka pendekatan yang digunakan adalah penelitian kepustakaan (library research). Adapun hasil penelitian ini adalah objek pendidikan dalam Islam mengacuk kepada beberapa kata. Pertama, kata ahl yaitu memiliki makna keluarga, istri, kerabat, atau orang yang tinggal di tempat yang sama. kata ahl juga bisa mengacu kepada berbagai kelompok-kelompok yang terbentuk dan dibentuk dalam realitas kehidupan umat manusia. Kedua, kata ‘asyirah memiliki pemaknaan yang variatif. Adapun penekanan makna yang paling dominan adalah keluarga dalam lingkup yang lebih besar bila dibandingkan keluarga dalam istilah ahl. Sehingga istilah ‘asyirah tersebut tidak hanya sebatas hubungan karena nasab, tetapi juga hubungan karena adanya kesamaan baik secara geografis atau tempat tinggal, suku, kabilah atau karena adanya komunikasi interaktif yang intens di antara sesama kelompok masyarakat yang ada.  Ketiga, istilah al-qurbu (القرب) lebih mengarah kepada keluarga yang diikat oleh persaudaraan, boleh jadi persaudaraan itu akibat adanya garis keturunan atau persaudaraan yang hanya sebatas karena adanya persamaan persepsi. Dengan demikian, dalam pendidikan Islam pendidikan tidak hanya fokus untuk bagaimana membelajarkan manusia sebagai individu, tetapi manusia dalam berbagai komunitas pun tetap mendapat perhatian serius dalam rangka mewujudkan tujuan pendidikan Islam yaitu teraktualisasikannya iman dan dan takwa kepada Allah SWT dalam diri.
Drying kinetics of organic parchment coffee beans (Coffea arabica L.) using microwave fluidised bed: Semi-theoretical modeling
Authors: Valle Vargas Marcelo Fernando , Durán Baron Ricardo , Alean Jader , Ciro Velasquez Héctor J.
Published: July 2022

The aim of this study was to model the drying kinetics of microwave and fluidised bed of parchment coffee bean (Coffea arabica L.) using a semi-theoretical approach. A completely randomized design with six treatments: three with microwave drying (MD) and the rest combined with fluidized bed drying (MFBD) was carried out. The drying curves were established until reaching a final moisture content between 10 to 12% w.b. The results indicated that the drying time decreased as the microwave power level increased. When MFBD was used, drying times increased approximately 4-fold compared to MD treatments. The values of effective diffusivity for coffee beans treated with MD and MFBD ranged from 0.913 to1.72×10-9 m2.s-1 and 0.23 to 0.42×10-9 m2.s-1, respectively. Although all the models presented high goodness of fit, the two-term model presented the highest R2 (0.9855 – 0.9978) and lowest RMSE (0.0128-0.0285). In general, all models adequately fitted the experimental data so they can be used to predict the drying kinetics, therefore they could be very useful in equipment design and optimization of the coffee drying process.
Monitoreo de material particulado fino y carbono negro, en microambientes de la ciudad andina de Manizales: estudio piloto
Authors: Gálvez Serna Angel David , González Duque Carlos Mario , Franco Ramírez Juan Felipe , Morales Betancourt Ricardo , Rincón Riveros Juan Manuel , Aristizábal Zuluaga Beatriz Helena
Published: July 2022

Manizales cuenta actualmente con un sistema de vigilancia de calidad del aire que mide concentraciones en aire ambiente de material particulado (PM, por sus siglas en inglés). Sin embargo, este sistema no permite conocer concentraciones de exposición en inmediaciones de vías. El ob-jetivo de este estudio fue realizar una primera aproximación a los niveles de exposición a material particulado fino (PM2.5) y carbono negro (BC) en algunas vías de la ciudad de Manizales, evaluando microambientes relacionados con los peatones en vías y como pasajeros de buses del transporte público. Se midieron concentraciones de material particulado fino PM2.5 y BC durante dos semanas por periodos de cinco horas al día en horas de la mañana. Se usaron dos fotómetros DustTrack modelos 8533 y un Microaetalómetro modelo AE51. Los datos fueron evaluados en función de cada microambiente y tres zonas de estudio en la ciudad. 

El valor obtenido de la mediana para las concentraciones de PM2.5 y BC en las vías analizadas, fue 10 % y 30 % menor en la zona oriente respecto al sector centro, indicando la relevancia del tráfico vehicular como fuente de emisión en la ciudad. Para el caso de los pasajeros de transporte público, las concentraciones expresadas como la mediana de PM2.5 y BC fueron 57 % y 54 % mayores comparadas con los peatones de las vías. Al interior del transporte público el porcentaje de aporte de BC fue aproximadamente del 41 % de la concentración total de PM registrado. Este es el primer estudio sobre exposición a estos contaminantes en Manizales; planteando la necesidad de seguir fortaleciendo análisis similares y usar los resultados como complemento para la gestión de calidad del aire en la ciudad.
EVOLUTION AND ANALYSIS OF SECURED HASH ALGORITHM (SHA) FAMILY
Authors: Khan Burhan Ul Islam , Olanrewaju Rashidah Funke , Morshidi Malik Arman , Mir Roohie Naaz , Mat Kiah Miss Laiha Binti , Khan Abdul Mobeen
Published: July 2022

With the rapid advancement of technologies and proliferation of intelligent devices, connecting to the internet challenges have grown manifold, such as ensuring communication security and keeping user credentials secret. Data integrity and user privacy have become crucial concerns in any ecosystem of advanced and interconnected communications. Cryptographic hash functions have been extensively employed to ensure data integrity in insecure environments. Hash functions are also combined with digital signatures to offer identity verification mechanisms and non-repudiation services. The federal organization National Institute of Standards and Technology (NIST) established the SHA to provide security and optimal performance over some time. The most well-known hashing standards are SHA-1, SHA-2, and SHA-3. This paper discusses the background of hashing, followed by elaborating on the evolution of the SHA family. The main goal is to present a comparative analysis of these hashing standards and focus on their security strength, performance and limitations against common attacks. The complete assessment was carried out using statistical analysis, performance analysis and extensive fault analysis over a defined test environment. The study outcome showcases the issues of SHA-1 besides exploring the security benefits of all the dominant variants of SHA-2 and SHA-3. The study also concludes that SHA-3 is the best option to mitigate novice intruders while allowing better performance cost-effectively.
WDSAE-DNDT BASED SPEECH FLUENCY DISORDER CLASSIFICATION
Authors: Pravin Sheena Christabel , Palanivelan M.
Published: July 2022

In this paper, Weight Decorrelated Stacked Autoencoder-Deep Neural Decision Trees (WDSAE-DNDT), a novel hybrid model is proposed for automating the assessment of children’s speech fluency disorders by discerning their disfluencies. In fluency disorder classification, it is imperative to know how each feature contributes to the disorder classification rather than the diagnosis itself and so the depth modified DNDT acts as the best discriminator since it is interpretable by its very nature. The WDSAE presents DNDT with a high-level latent representation of the disfluent speech. A fusion feature vector was built by combining the prosodic cues from disfluent speech segments combined with the WDSAE-based Bottleneck features. The proposed hybrid model was compared with the performance of the experimented baseline models. Further analysis was carried out to check the impact of tree cut points for each feature and epochs on the accuracy of prediction of the hybrid model. The proposed hybrid model when trained on the fusion feature set has shown appreciable improvement in the area under the Receiver Operating Characteristics (ROC) curve, classification accuracy, Kappa statistical value, and Jaccard similarity index. The WDSAE-DNDT demonstrates high precision than the baseline models in setting clinical benchmark to distinguish subjects with dysphemia from those with Specific Language Impairment.
SELF-ORGANIZING RESERVOIR NETWORK FOR ACTION RECOGNITION
Authors: Lee Gin Chong , Loo Chu Kiong , Liew Wei Shiung
Published: July 2022

Current research in human action recognition (HAR) focuses on efficient and effective modelling of the temporal features of human actions in 3-dimensional space. Echo State Networks (ESNs) are one suitable method for encoding the temporal context due to its short-term memory property. However, the random initialization of the ESN's input and reservoir weights may increase instability and variance in generalization. Inspired by the notion that input-dependent self-organization is decisive for the cortex to adjust the neurons according to the distribution of the inputs, a Self-Organizing Reservoir Network (SORN) is developed based on Adaptive Resonance Theory (ART) and Instantaneous Topological Mapping (ITM) as the clustering process to cater deterministic initialization of the ESN reservoirs in a Convolutional Echo State Network (ConvESN) and yield a Self-Organizing Convolutional Echo State Network (SO-ConvESN). SORN ensures that the activation of ESN’s internal echo state representations reflects similar topological qualities of the input signal which should yield a self-organizing reservoir. In the context of HAR task, human actions encoded as a multivariate time series signals are clustered into clustered node centroids and interconnectivity matrices by SORN for initializing the SO-ConvESN reservoirs. By using several publicly available 3D-skeleton-based action recognition datasets, the impact of vigilance threshold and reservoir perturbation of SORN in performing clustering, the SORN reservoir dynamics and the capability of SO-ConvESN on HAR task have been empirically evaluated and analyzed to produce competitive experimental results.
A formação de professores no âmbito de competências do raciocínio geométrico: uma revisão de literatura
Authors: Encarnação Abel , Neto Teresa , Breda Ana
Published: July 2022

Este artigo apresenta uma revisão de literatura no âmbito de um projeto de doutoramento, em curso, que incide sobre o conhecimento e competências geométricas de professores de Matemática, no sentido de sustentar investigação sobre um programa de formação contínua de professores angolanos. Teve como objetivo caraterizar práticas de formação de professores de Matemática em contexto de Geometria. Foram estabelecidos cinco termos de pesquisa, que coincidem com as palavras-chave, em três diferentes línguas cujas fontes foram seleccionadas tendo em conta a garantia de qualidade, apoiando-se para tal na escolha de bases de dados e repositórios para pesquisa tendo em consideração critérios previamente definidos para a composição do corpus documental composto por 15 artigos desenvolvidos em diferentes contextos, que foram objeto de análise. Um dos resultados da análise efetuada colocou em evidência o parco conhecimento geométrico dos professores, o que sugere a necessidade de projetar ações específicas de formação em contexto de raciocínio geométrico nos atuais planos de formação contínua de professores de Matemática visando, por um lado, potenciar o professor com conhecimentos e habilidades para melhor lecionar as matérias sobre estes conteúdos e, por outro, despertar no aluno o interesse pela Geometria.
Hubungan Ketahanan dan Kerawanan Pangan dengan Social Capital dan Food Choice Rumah Tangga Pra Sejahtera di Kelurahan Dukuh, Kecamatan Sidomukti, Kota Salatiga
Authors: Renyoet Brigitte Sarah , Lakajen Orissa Kristinawati , Sanubari Theresia Pratiwi E.
Published: July 2022

Ketahanan pangan bertujuan untuk menjamin ketersediaan dan konsumsi pangan yang cukup, aman, bermutu hingga memiliki gizi seimbang di suatu wilayah yang ditentukan oleh ketahanan pangan keluarga. Namun, kenyataannya tidak semua rumah tangga dapat mengakses, dan menyediakan pangan seperti yang dialami oleh rumah tangga keluarga pra-sejahtera. Faktor lain yang dapat berpengaruh pada pemenuhan kebutuhan adalah social capital dan food choice. Penelitian ini bertujuan untuk mengetahui keterkaitan hubungan ketahanan dan kerawanan pangan dengan social capital dan food choice pada rumah tangga pra-sejahtera di Kelurahan Dukuh, Sidomukti, Kota Salatiga. Penelitian ini menggunakan metode kuantitatif deskriptif yang dilakukan di kelurahan Dukuh, Kecamatan Sidomukti, Kota Salatiga. Responden yang digunakan adalah semua keluarga pra-sejahtera di Kelurahan Dukuh berjumlah 77 responden. Hasil uji Chi Square menunjukkan bahwa terdapat hubungan antara social capital dengan ketahanan pangan dan kerawanan pangan rumah tangga pra-sejahtera di Dukuh dengan bukti nilai p = <0,05 (0,013). Sementara, pada hasil uji Chi Square pada food choice terhadap ketahanan dan kerawanan pangan menunjukkan nilai p= >0,05 (0,791) atau tidak terdapat adanya hubungan. Mayoritas rumah tangga pra-sejahtera di Dukuh berada dalam kategori kerawanan pangan tingkat sedang (50,64%), dengan social capital (80,41%) dan food choice (68,3%) dalam kategori cukup baik. Dengan demikian, dapat disimpulkan bahwa social capital menjadi salah satu faktor yang mempengaruhi ketahanan dan kerawanan pangan rumah tangga pra-sejahtera di Dukuh.
Identifikasi Kimia Serta Gambaran Pengetahuan Siswa Terhadap Boraks, Formalin dan Rhodamine-B Pada Jajanan Di SMA Muhammadiyah 1 Gresik
Authors: Tiadeka Pemta , Solikhah Desty Muzarofatus , Karimah Maulidatul
Published: July 2022

Saat ini, penggunaan bahan kimia berbahaya sebagai bahan tambahan pangan (BTP) masih menjadi masalah besar bagi Indonesia. BTP yang marak digunakan oleh produsen jajanan adalah boraks, formalin dan rhodamine-B. Banyak kasus keamanan pangan yang kurang terjamin ditemukan di lingkungan sekolah dengan konsumen terbanyak adalah siswa. Penelitian ini bertujuan untuk melakukan identifikasi ketiga BTP serta menganalisa pengetahuan siswa tentang BTP dan cara deteksi bahan kimia berbahaya pada makanan. Penelitian ini bersifat deskriptif kuantitatif. Metode identifikasi kimia pada penelitian ini menggunakan tes kit boraks, formalin dan rhodamine B. Pengukuran tingkat pengetahuan dilakukan dengan cara memberikan kuisioner pada siswa. Sampel penelitian ini adalah 8 jenis jajanan yang paling banyak terjual  di lingkungan SMA Muhammadiyah 1 Gresik serta 19 responden siswa SMA tersebut dengan teknik purposive sampling. Berdasarkan hasil analisa secara kimia diperoleh hasil bahwa sebanyak 12,5% sampel mengandung boraks, 25% mengandung formalin dan 12,5% terdapat rhodamine-B. Jenis sampel yang terdeteksi ada bahan kimia berbahaya adalah sosis dan minuman bewarna terang. Selanjutnya, dari 19 responden diperoleh hasil sebanyak 87,21% siswa memiliki pengetahuan yang baik tentang BTP sedangakn 58% siswa menunjukkan kurang memiliki pengetahuan identifikasi bahan kimia pada pangan.  Dengan adanya jajanan yang masih mengandung formalin dan rhodamine-B serta pengetahuan siswa yang kurang tentang cara deteksi bahan kimia tersebut, maka diharapkan pihak sekolah memberikan edukasi yang optimal kepada siswa sehingga dapat mencegah dampak penyakit yang ditimbukan akibat mengkonsumsi jajanan yang kurang bergizi.
Identification of Seagrass Ecosystem in the Waters of the Makasar Island, Baubau City
Authors: Sirza La ode Muhammad Junaidin , Cahyani Waode Sitti , Bugis Nila Nikmatia , Hasanah Nur
Published: July 2022

Ekosistem lamun merupakan salah satu ekosistem penting di wilayah pesisir dan memiliki produktivitas yang tinggi. Keberadaan lamun memiliki peranan penting bagi biota laut lainnya, manusia, dan lingkungan sehingga kemungkinan penurunan kualitas dan kuantitasnya dapat mengurangi manfaat yang dihasilkan oleh padang lamun dan memberikan dampak yang cukup signifikan bagi lingkungan sekitarnya. Penelitian ini bertujuan untuk mengidentifikasi jenis-jenis lamun dan persentase tutupan lamun di Perairan Pulau Makasar, Kota Baubau. Penelitian ini dilaksanakan pada Februari 2020 di Perairan Pulau Makasar, Kota Baubau, Sulawesi Tenggara. Pengamatan kondisi tutupan lamun dan kerapatan lamun dilakukan menggunakan transek kuadrat 0,5 m x 0,5 m dengan panjang transek garis yaitu 100 m. Hasil penelitian ini menunjukan jenis lamun yang dijumpai di Perairan Pulau Makasar yakni Enhallus accoroides, Cymodocea serullata, Halophila ovalis dan Thalassia hemprichii dengan luas tutupan lamun berkisar antara 7,39 – 51,7 %. Luas tutupan lamun di Pulau Makasar termasuk kategori buruk dan rusak. Paramater fisika kimia perairan masih optimum dalam mendukung perkembangan lamun.
Effect of Additional Extract Curcuma (Curcuma xanthorrhiza) on Commercial Feed on Growth and Survival Rate of Tilapia Seeds (Oreochromis niloticus)
Authors: Ardiansyah  , Rizal Achmad
Published: July 2022

Penelitian bertujuan untuk mengetahui pengaruh penambahan ekstrak temulawak (Curcuma xanthorrhiza) pada pakan komersil terhadap pertumbuhan dan sintasan benih ikan nila (Oreochromis niloticus). Organisme uji yang digunakan dalam penelitian yaitu benih ikan nila dengan bobot rata-rata 1,55 gram sebanyak 200 ekor yang diperoleh dari Balai Benih Ikan Tulo, Kecamatan Dolo, Kabupaten Sigi. Penelitian ini menggunakan desain Rancangan Acak Lengkap (RAL) yang terdiri dari empat perlakuan dengan lima ulangan. Perlakuan A: tanpa penambahan ekstrak temulawak; Perlakuan B: penambahan ekstrak temulawak 4 g/kg pakan; Perlakuan C: penambahan ekstrak temulawak 8 g/kg pakan; dan Perlakuan D: penambahan ekstrak temulawak   12 g/kg pakan. Ekstrak temulawak yang telah siap kemudian dimasukan kedalam botol semprotan sesuai dosis yang telah ditentukan. Biomassa dan bobot organisme uji ditimbang pada awal dan akhir pemeliharaan. Pengukuran kualitas air meliputi suhu, pH, oksigen terlarut, dan amonia. Hasil penelitian menunjukkan bahwa perlakuan berpengaruh nyata (p<0,05) terhadap bobot mutlak benih ikan nila. Persentase bobot mutlak dan sintasan pada benih ikan nila tertinggi diperoleh pada perlakuan D, masing-masing sebesar 1,423 g dan 94%.
Determinants influencing the intention to switch internet service providers of consumers: Application of transaction costs theory
Authors: Hien Luc Manh , Van Pham Thi Thuy , Tram Nguyen Thi Anh , Ha Le Thi Hai , Dao Mai Thi Anh
Published: July 2022

Customer loyalty, retention, and repurchase intentions give favorable outcomes for providers, and service switching and switching intentions imply unfavorable outcomes (Bansal & Taylor, 1999). The aim of this study is to investigate the determinants influencing the intention to switch internet service providers of Vietnamese consumers. Data for this study were collected from a survey of 564 Vietnamese consumers in Hanoi who have bought internet service. Through quantitative research methods with some techniques, such as Cronbach’s alpha and exploratory factor analysis, the research shows that 9 factors influence the intention to switch internet service providers of Vietnamese consumers. The regression model among variables shows that influencing level clarity of the factors on the intention to switch internet service providers of Vietnamese consumers. Therefore, the empirical findings show that the intention to switch internet service providers of Vietnamese consumers has a mediating role in the relationship between service providers. The findings of this study suggest that managers need to focus on investing and researching to understand customers’ attitudes towards competitors’ products better, thereby they can proactively develop marketing programs to negatively influence the intention to switch. This article makes a new discovery about the intention to switch internet service providers for Vietnamese consumers
Medication changes and potentially inappropriate prescribing in older patients with significant polypharmacy: a secondary analysis of the SPPiRE trial
Authors: McCarthy Caroline , Flood Michelle , Clyne Barbara , Smith Susan , Wallace Emma , Boland Fiona , Moriarty Frank
Published: July 2022

Background

Number of medicines and medicines appropriateness are often used as
outcome measures to evaluate the effectiveness of deprescribing
interventions. The aim of this study was to evaluate changes in
prescribing, potentially inappropriate prescriptions (PIP) and
prescribing of low-value medicines during the SPPiRE trial.

Methods

We retrospectively analysed trial prescription data from 51 general
practices with 404 participants aged ≥65 years and prescribed ≥15 repeat
medicines. Repeat medications at baseline and follow-up
(~1 year later) were assigned Anatomical Therapeutic
Classification (ATC) codes. Outcomes were the most commonly prescribed
and potentially inappropriately prescribed drug groups, the most
frequently discontinued or initiated drug groups and the number of
changes per person between baseline and follow-up.

Results

There were 7,051 medicines prescribed to 404 participants at baseline.
There was a median of 17 medicines (IQR 15-19) at baseline and 16 (IQR
14-19) at follow-up. PIP represented 17.1% of prescriptions at baseline
and 15.7% (n=6,777) at follow-up. There were reductions in the
prescription of most drug groups with the largest reduction in
antiplatelet prescriptions. Considering medication discontinuations,
initiations and switches, there was a median of five medication changes
per person (range 0-30, IQR 3-9) by follow-up. There were 95 low-value
prescriptions at baseline reducing to 78 at follow-up.

Conclusion

The number of medication changes per person was not reflected by
summarising medication count at two time points, highlighting the
complexity of prescribing for patients with polypharmacy. Frequent
medication changes has potentially important implications for patients
in terms of adherence and medication safety.

Key words: Multimorbidity, polypharmacy, cluster randomised controlled
trial, deprescribing, potentially inappropriate prescribing

The SPPiRE trial was registered prospectively on the ISRCTN registry
(ISRCTN12752680).
The First Full-Genome Characterization and Phylogenetic Analysis of a Potential Recombinant Bovine Herpesvirus Type 1 Isolated in China
Authors: Chen Hongjun , Guo Weiqiang , Xie Jia , Liu Jingyi , Qian Yingjuan , Jung Yong-Sam
Published: July 2022

Bovine herpesvirus type 1 (BHV-1) is a virus of causing bovine
respiratory disease that poses significant threat to the cattle
industry. The prevalence of BHV-1 has recently increased in China.
However, information about the prevalent isolates is scarce. In this
study, we identified a novel strain of BHV-1, referred to as BHV SHJS,
isolated from nasal swabs of Holstein cows in 2020 of China. The genome
of BHV SHJS is 1,35,102 bp in length and highly similar to SP1777
(KM258883.1) strain with an identity of 99.64 % . Mutations,
insertions, or deletions mainly occur in UL12, UL19, UL27, UL37, UL42,
UL44, UL46, UL47, US6, US7, and US8 relative to the different genomic
coordinates. Phylogenetic analyses of immunogenic gene (gB, gC, and gD)
revealed that BHV SHJS and other China outbreak strains were displayed
on different branches with commonly used vaccine strains. Recombination
analysis shown that BHV SHJS could persist even with BoviShield IBR MLV
and Arsenal IBR MLV vaccines, suggesting that these vaccines should not
completely prevent BHV SHJS infection. These analyses partially explain
why the vaccines only partially protect against BHV-1 outbreaks in
China. In conclusion, we identified a novel and potential recombinant
BHV-1 strain and for the first time characterized BHV-1 genome with a
different evolutionary origin from that of known strains prevalent in
China. This study will enrich our knowledge regarding BHV outbreak
strains in China and contribute to the prevention and pathogenic studies
of BHV-1.
Abdominal sacrohysteropexy for large iatrogenic early postpartum vesicouterine fistula: An innovative technique
Authors: Geoffrion Roxana , Badowski Sophia
Published: July 2022

Sacrohysteropexy is a surgical technique employed for the surgical
treatment of uterine prolapse when uterine preservation is desired.
Vesicouterine fistulae are rare iatrogenic complications of difficult
operative childbirth, typically via caesarean section. If further
childbearing is planned, uterus-sparing fistula closure in layers, with
interposition grafts, has been described. To further decrease recurrence
rates, temporary suspension of the uterus away from the fistula site can
be achieved via sacrohysteropexy with absorbable biologic graft. The
graft eventually resorbs with return of the uterus to its normal pelvic
anatomic location.
Interrogating 1000 Insect Genomes for NUMTs: A Risk Assessment for Species Scans
Authors: Hebert Paul , Bock Dan , Prosser Sean
Published: July 2022

The nuclear genomes of most animal species include segments of the
mitogenome, but the count of these NUMTs varies greatly. This study
examines the incidence of NUMTs derived from a 658 bp region of the
cytochrome c oxidase I (COI) gene as a proxy for other coding regions of
the mitochondrial genome. Analysis focuses on the most diverse group of
terrestrial organisms, insects, because COI-based identification systems
play a key role in clarifying their diversity, an essential antecedent
to genome sequencing. Nearly 10,000 COI NUMTs ≥ 100 bp were detected in
the genomes of 1,002 insect species with a range from 0–443. NUMT
counts were similar among congeners, but differences among genera in a
family were often large with genome size explaining 56% of the
mitogenome-wide variation in counts. While many of these NUMTs possessed
an indel or premature stop codon allowing their exclusion, the others
could complicate species diagnosis as they averaged 10.1% divergence
from their mitochondrial homologue. The count of NUMTs varies widely
among insect lineages, peaking in groups that employ direct development
or incomplete metamorphosis. They can raise the apparent species count
by up to 22% when the 658 bp barcode region is examined while shorter
targets (300 bp, 150 bp) elevate exposure (58–111%) to “ghost”
species. As a result, NUMTs represent a particular complication for
protocols (e.g., eDNA, metabarcoding) which employ short amplicons for
biodiversity assessments.
Experimental investigation on the influencing factors of preparing three-phase foam
Authors: Wang Bin , Zuo Sheng , Zuo Xixi , Ma Xiangmei
Published: July 2022

A three-phase foam is considered one of the promising advanced materials for fighting fires. However, the preparation conditions, cost and effect are key factors for industrial applications. In this study, new three-phase foam systems with fly ash and a complex surfactant are proposed. Five types of surfactants alcohol polyoxyethylene ether sodium sulfate, coconut oil diethanolamine, sodium lauryl sulfate, polyacrylamide and polyether-modified silicone resin emulsion were selected as foaming agents. Through laboratory experiments, the effect on the expansion ratio and foam stability of the surfactant type/concentration, fly ash particle concentration/size and pH were investigated. The foaming condition was determined by numerical optimization. The results of this study may serve as a reference for understanding the preparation of a novel threephase foam. It is hoped that this work could provide useful guidance for the preparation of efficient three-phase fire-extinguishing foam for the safe guarding of process safety in the field of chemical production, transportation, and storage suitable for drug delivery than Al12P12 and Al12N12 based on their recovery times.
The impact of abdominal aortic aneurysm diameter on the outcome of endovascular aortic repair
Authors: Batinic Nikola , Kokovic Tijana , Nikolic Dragan , Manojlovic Vladimir , Till Viktor , Budinski Slavko
Published: July 2022

Introduction. Abdominal aortic aneurysm diameter is one of the most important
parameters in the diagnostic and therapeutic algorithm for aneurysm
follow-up. Currently, two therapeutic modalities are used: open surgery and
endovascular aortic repair. The aim of this study is to analyze the impact
of the maximum transverse diameter of the abdominal aortic aneurysm on the
incidence of general and specific complications. Material and Methods. The
retrospective study included 75 patients with infrarenal abdominal aortic
aneurysm who underwent endovascular aortic repair in the period from July
2008 to January 2020. The patients were divided into two groups: group A
with an abdominal aortic aneurysm size ? 5.9 cm, and group B with an
abdominal aortic aneurysm size ? 6.0 cm. Results. A total of 41.3% of
patients presented with a maximum transverse aneurysm diameter of ? 5.9 cm,
and 58.7% of patients had ? 6.0 cm. Of comorbid diseases, chronic
obstructive pulmonary disease was more prevalent in patients with a large
abdominal aortic aneurysm (group A 25.8%; group B 59.1%). None of the other
comorbidities showed a statistically significant difference between the two
groups of patients. Early complications were present in a total of 14.7% of
patients, of which 12.9% of patients with a small and 15.9% with a large
abdominal aortic aneurysm. Late complications occurred in a total of 18.7%
of patients, in 9.7% of patients with a small and 25% of patients with a
large abdominal aortic aneurysm. Conclusion. Patients with abdominal aortic
aneurysms with a maximum transverse diameter of 6 cm and larger, present
with a higher rate of late postoperative complications, increase in
aneurysmal sac on control multislice computed tomography angiography, and
have a worse prognosis compared to patients with smaller abdominal aortic
aneurysms.
Acute kidney injury in critically ill patients in the intensive care units
Authors: Markovic Mira , Popovic Milica , Strazmester-Majstorovic Gordana , Azasevac Tijana , Petrovic Lada , Mitic Igor
Published: July 2022

Introduction. Acute kidney injury is a serious complication in critically ill
patients in the intensive care units. The incidence varies from 20% to as
high as 80%. Acute kidney injury is associated with expensive supportive
therapy, high morbidity and poor outcomes. The aim of this study was to
determine the incidence, causes, risk factors, treatment options and
treatment outcomes of acute kidney injury in critically ill patients.
Material and Methods. The study included 44 patients, with an average age of
67 ? 13.20 years. The data were collected during a three-month prospective
study at the Department of Emergency Internal Medicine of the Clinical
Center of Vojvodina, Novi Sad. Demographic data were collected from the
medical records, as well as data on blood tests, comorbidities, use of
nephrotoxic agents, and treatment of these patients. Results. Of the 44
patients who were included in the study, 20% developed acute kidney injury.
De novo acute kidney injury was diagnosed in 51.22% and 48.78% of patients
had acute-onchronic renal failure. The most common type of acute kidney
injury was pre-renal, 80.95%. Comorbidities were present in all patients,
most often arterial hypertension, in 52.4% of patients. Complete recovery of
kidney function was found in 42.86% of patients and the mortality was
28.57%. Conservative therapy was used in 90.48% of patients, while 9.52% of
patients required renal replacement therapy. Conclusion. De novo acute
kidney injury was found in approximately half of the critically ill patients
in the intensive care unit, mainly older patients with comorbidities. The
most common type of acute kidney injury was pre-renal. Older age and
comorbidities were associated with poor outcomes and high mortality.
Acinetobacter superinfection in elderly COVID-19 patients with pneumothorax - a report of two cases
Authors: Detanac Dzemail , Detanac Dzenana , Stojkovic Dragan , Ceranic Lejla
Published: July 2022

Introduction. Coronavirus disease 2019 is an infectious disease that
primarily affects the lungs. Since the pandemic of severe acute respiratory
syndrome coronavirus 2 continues and a large number of cases are registered
worldwide, the knowledge about the virus and virus-related complications is
growing as well. Pleural complications, pneumothorax, and empyema are
important issues affecting better patient survival. Bacterial
superinfections may cause complications of coronavirus disease 2019.
Knowledge about the incidence of superinfections, microbiological causes,
treatment, and outcomes of the disease is incomplete. Case Report. We
present two oxygen-dependent patients with coronavirus disease 2019 who
developed pneumothorax and empyema during hospitalization, three weeks after
the onset of coronavirus disease 2019 symptoms. Multidrug-resistant
Acinetobacter spp. was isolated from the thoracic drain. Conclusion.
Pneumothorax may occur at any stage of coronavirus disease 2019 and is not
always associated with the severity of viral infection. Empyema due to
coronavirus disease 2019 pneumonia is rare and occurs as a superinfection of
the pleural effusion. Excessive use of antibiotics in the treatment of
hospitalized patients with coronavirus disease 2019 may increase the risk of
nosocomial infections caused by multidrug-resistant bacteria.
Systemic treatment of hepatocellular carcinoma in a patient with hemophilia A: A case report
Authors: Radic Jelena , Kolarov-Bjelobrk Ivana , Vasiljevic Tijana , Vranjkovic Bojana , Vidovic Vladimir , Petrovic Nemanja
Published: July 2022

Introduction. Hepatocellular carcinoma is a serious problem for patients with
hemophilia. Hepatitis C virus infection is the most common comorbidity in
adult patients with inherited bleeding disorders, including hemophilia. Case
Report. This is a case report of a 65-year-old male patient with hemophilia
A and hepatocellular carcinoma. Sorafenib treatment was initiated at a dose
of 400 mg/day, after a 50% dose reduction. In order to prevent bleeding
episodes, prophylactic doses of replacement plasma-derived factor VIII
concentrate (40 U/kg of body weight three times a week) were introduced. Our
patient received a total of ten cycles of sorafenib therapy, in good general
condition, without bleeding episodes. Conclusion. Differential chemotherapy
is not contraindicated in patients with inherited bleeding disorders,
provided that adequate hemostasis is achieved. In such cases, a
multidisciplinary approach is necessary for the management of hemophilia
during systemic cancer treatment.