bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of the mechanical densification process in wood material on the surface adhesion strength of varnishes
Authors: Atilgan Abdi , Burdurlu Erol , Atar Musa , Yasar Sekip Sadiye
Published: September 2024

This research aimed to determine the impact of the mechanical densifying process of wood material on the varnish surface adhesion strength. Specimens from black pine (Pinus nigra) and Uludag fir (Abies bornmuelleriana Mattf.) were subjected to densification in a hydraulic press at 140 °C to the extent of 25% and 50% in the radial direction. While densification increased the surface adhesion strength of the varnish layer in black pine, the value decreased in fir. Regarding the interaction between densification ratio, surface treatment, and wood type, the highest surface adhesion strength of the varnish layer was found in black pine + unsanded surface + 25% densification, and the lowest was in Uludag fir + unsanded surface + 50% densification. It can be stated that the densification process creates high adhesion values for the polyurethane varnish in the black pine wood type. The sanding process has an intensifying effect on these values, and the products that were obtained from the polyurethane varnished samples do not require sanding. Considering these situations can provide significant advantages in projects with wood materials subjected to the densification process.
Performance of thermally modified Tauari (Couratari sp.) wood against fungal and termite biodeterioration
Authors: Silvares Paulo H. S. , Reis Miquéias S. , Queiroz Érica P. P. , Santos Vaniele B. , Maffioletti Fernanda D. , Nascimento Alexandre M. , Mendonça Adriano R. , Paes Juarez B. , Andrade Fernando W. C. , Batista Djeison C.
Published: September 2024

Thermal modification is a process capable of improving properties affecting wood performance, such as biological durability. This study aimed to assess the potential of thermal modification in enhancing the resistance of Couratari sp. wood to deterioration by Trametes versicolor, Nasutitermes corniger, and Cryptotermes brevis. Five treatments were analyzed, represented by the untreated and thermally modified wood at 180, 190, 200, and 210 °C. The wood’s chemical composition and resistance to biodeterioration in laboratory tests were evaluated. Thermal modification, especially at 210 °C, altered the chemical composition and increased the wood’s durability class against the fungus. However, the process did not affect termite attack. There was a significant positive correlation between corrected mass loss and hemicellulose and total extractive contents, as well as mass loss caused by T. versicolor and lignin and hemicellulose contents. The use of thermal modification in 190 °C is recommended for Couratari sp. wood due to its enhanced biological durability, with 210 °C being particularly effective.
Posterior Reversible Encephalopathy Syndrome Due to Vitamin D Toxicity
Authors: O’Brien Mackenzie , Koh Eunice , Barsh Gabrielle Russo , Zhou Melissa S. , Aguilar Abisad Daniela , Chang Nathan
Published: September 2024

Although toxicity from excessive exogenous vitamin D supplementation is rare, a range of symptoms can occur, most of which result from hypercalcemia. We report a novel case of posterior reversible encephalopathy syndrome (PRES) in a young child who required intensive care after presenting with hypercalcemia, hypertensive emergency, acute kidney injury, and hypercarbic respiratory failure, which ultimately were attributed to vitamin D toxicity (VDT). We report a young child who developed PRES in association with VDT. Our report informs pediatric outpatient, hospitalist, and intensivist providers about rare but life-threatening complications from hypervitaminosis D, adds VDT to the differential diagnosis for children with similar presentations, and highlights the importance of vitamin supplementation safety guidance for families.
Curiously interpreted heritage, or how a Catacomb saint in Tokaj-Hegyalja became a pope?
Authors: Kis Tímea N.
Published: September 2024

The relics of the Catacomb Saint Urban, which are preserved in Monok, Hungary, were falsely identified as the mortal remains of Pope Urban I in 1983. Spreading of the Pope's patronage of preserving the grapes from the spring frost damage led to the development of his new local cult.

The study deals with this misidentification and its consequences, with the circumstances of the baroque reliquary's arrival to the village in 1771, with its procurer and the real reason of the purchase, finally with its translatio to the Holy Cross altar in the chapel located in the Andrássy Castle.
The influence of age on gambling problems worldwide: A systematic review and meta-analysis of risk among younger, middle-aged, and older adults
Authors: Dellosa Georgia , Browne Matthew
Published: September 2024

Background and Aims

Problem gambling (PG) represents a significant public health concern with widespread effects in various cultures and regions globally, with younger individuals and males at a particularly higher risk. This disparity is attributed to a mix of cultural, developmental, and biological influences. To date, there has not been a comprehensive examination to determine whether this risk pattern holds consistently across different jurisdictions.

Methods

We performed a systematic review and meta-analysis using the PRISMA framework, identifying 21 eligible studies from 18 countries, encompassing 156,249 participants (47.6% male and 52.4% female).

Results

The studies varied considerably by region (Asia: 19%, Europe: 52%, Oceania: 19%, North America: 10%), the diagnostic criteria for PG, and participation rates in gambling (ranging from 12% to 92%). Data on PG prevalence was categorised by gender and three age groups (young: 18–35, middle: 30–55, and older: 45–65). Using a random-effects meta-analysis, we found a global PG prevalence of 1.9%. Europe reported a significantly lower prevalence (1.3%) compared to North America (5.3%). Men were found to be 3.4 times more likely than women to engage in problem gambling, although the gap narrows in North America. The young demographic showed a 1.51 times higher likelihood of reporting PG compared to the middle-aged group, whereas older adults were 0.80 times less likely to report PG. Notably, age-related effects varied significantly across regions.

Conclusions

Our findings confirm that age and gender significantly influence PG risk across cultures, with significant heterogeneity observed across jurisdictions.
STRATEGI IMPLEMENTASI PERJANJIAN KERJA LAUT BAGI AWAK KAPAL PERIKANAN: STUDI KASUS DI PELABUHAN PERIKANAN SAMUDERA NIZAM ZACHMAN JAKARTA
Authors: Nugroho Kun Budi , Suherman Agus , Mudzakir Abdul Kohar , Hernuryadin Yayan
Published: September 2024

Perjanjian kerja laut (PKL) dibuat sebagai perlindungan atas risiko kerja bagi awak kapal perikanan. Pelabuhan Perikanan Samudera Nizam Zachman (PPSNZ) merupakan pelabuhan perikanan terbesar di Indonesia, sehingga PKL menjadi sangat penting untuk diimplementasikan. Penelitian ini bertujuan untuk menganalisis pelaksanaan PKL di PPSNZ, merumuskan alternatif strategi, dan menentukan prioritas strategi implementasi PKL di PPSNZ.  Penelitian dilaksanakan pada Desember 2022 sampai April 2023. Metode deskriptif digunakan dengan pendekatan studi kasus. Wawancara dilakukan terhadap 100 responden yang ditentukan melalui purposive sampling. Analisis SWOT dan AHP digunakan dalam menganalisis data. Implementasi kebijakan mengacu pada teori George C. Edwards III (1980). Hasil penelitian menunjukan bahwa PKL bagi awak kapal perikanan telah diimplementasikan di PPSNZ. Terdapat beberapa kendala dalam implementasi PKL di PPSNZ seperti: adanya awak kapal yang kabur, keterbatasan pemahaman awak kapal, lemahnya basis data dan kurangnya peran asosiasi awak kapal. Urutan prioritas strategi implementasi PKL di PPSNZ adalah mengoptimalkan sumber daya, menciptakan sistem berbasis elektronik dan terintegrasi, pendampingan dan pemberlakuan sanksi, serta sosialisasi.Sea work agreements (PKL) are made as protection against the work risks for fishing vessel crew. Nizam Zachman Ocean Fishing Port (PPSNZ) is the largest fishing port in Indonesia, so PKL is very important to be implemented. This research aims to analyze the implementation of PKL in PPSNZ, formulate alternative strategies, and determine strategic priorities for implementing PKL in PPSNZ. The research was carried out from December 2022 to April 2023. A descriptive method was used with a case study approach. Interviews were conducted with 100 respondents determined using purposive sampling technique. SWOT and AHP analysis were used to analyze the data. Policy implementation refers to the theory of George C. Edwards III (1980). The research results show that PKL for fishing vessel crews has been implemented at PPSNZ. There are several obstacles in the implementation of PKL in PPSNZ such as: crew members who run away, limited understanding of fishing vessel crews, weak databases, and lack of role of ship crew associations. The order of priority for the PKL implementation strategy at PPSNZ is optimizing existing resources, creating an electronic and integrated system, assistance and imposition of sanctions, and socialization.
Exploring the Role of Food in Gothic Literature
Authors: Pino Alessandra
Published: September 2024

This article investigates the significance of food consumption within the context of Gothic literature, shedding light on how seemingly mundane food and drink items are reinterpreted from a cultural memory perspective within this genre. From Mary Shelley’s Frankenstein to Daphne du Maurier’s Rebecca, food in Gothic literature reveals that true danger often lurks within the home. Cultural memory functions as a spectral conduit, conveying messages from the past to serve present purposes. Beginning with Mary Shelley’s Frankenstein (1818), the way in which food humanises Dr Frankenstein’s unnatural creation, prompts readers to question the true nature of monstrosity. The creature’s diet of nuts and berries, eschewing meat, challenges conventional notions of sustenance and appetite, offering early insights into the impact of industrialisation on food production during the nineteenth century. In Charlotte Brönte’s Jane Eyre (1847), food symbolises strength, weakness and oppression, as evidenced by scenes involving burnt porridge and acts of quiet rebellion through cake. In Bram Stoker’s Dracula (1897), meals initially serve as a source of comfort and familiarity for Jonathan Harker before they simply turn into fuel to combat the Count. Daphne du Maurier’s Rebecca (1938) uses food to underscore social hierarchies and power dynamics. This article presents a theoretical framework for food studies within the context of Gothic literature, exploring the cultural memory aspects associated with consumption in classic Gothic fiction.
Soma
Authors: Dalby Andrew
Published: September 2024

An outline of the nature of the ritual drink soma (Sanskrit) or haoma (Avestan) as described in ancient Indo-Iranian poetic traditions: how it was obtained, prepared, and consumed; what effects were reported. Several proposed identifications of the plant source are briefly discussed. The identification that is probably correct (Ephedra species) is placed in its context.
Determination of the exploitation parameters of the Bled El Hadba phosphate deposit, Algeria
Authors: Bekhouche Youcef , Nettour Djamel , Chaib Rachid
Published: September 2024

The beneficiation of mineral resources not only bolsters a country's economy but also improves quality of life and fosters sustainable growth. The development of the phosphate mine in the Bled El Hadba region represents a pivotal move to meet increasing demand. This study aims to develop a comprehensive 3D geographic model of the deposit, estimate its phosphate reserves, and assess the parameters and characteristics for effective exploitation. Utilizing the block model method in Surpac 6.6.2, a detailed analysis is achieved that supports informed decision-making for sustainable resource management. This approach underscores the importance of technological innovation in the strategic planning and efficient utilization of mineral resources.
The results revealed total reserves of 425,304,000 m³, equivalent to 893,138,400 tons, with an average grade of 21.65 %. The stripping ratio was determined to be 3.3:1. These findings provide valuable insights into the deposit's potential and the optimal depth range for extracting the highest concentration of P2O5. For detailed extraction planning and estimating P2O5 concentration over five-year periods from 2023 to 2066, with an average annual phosphate ore production of 20.7 million tons, Minesched software was utilized. This comprehensive approach ensures efficient resource management and maximizes the economic return from the deposit. These findings have profound implications for enhancing both the efficiency and sustainability of Algeria's mining industry. By securing a consistent supply of phosphate products, particularly for agriculture, this research addresses the rising demand for phosphates. Additionally, the data can inform strategic planning, enabling optimized resource extraction and reduced environmental impact. This contributes not only to the immediate needs of the industry but also to the long-term economic and ecological sustainability of the region. Ultimately, the study supports sustainable development by balancing industrial growth with environmental stewardship, ensuring that future generations can continue to benefit from these vital resources.
Consideration of DC/DC converter for photovoltaics with soft switching with modified push-pull current source inverter circuit
Authors: Ivakhno Volodymyr , Zamaruiev Volodymyr , Plakhtiy Oleksandr , Nerubatskyi Volodymyr , Filipieva Maryna
Published: September 2024

The object of research is the power part of the two-stage converter. The paper evaluates the parameters of the power part of the two-stage converter with transformer isolation, designed for the transfer of solar battery energy to the 400 V constant voltage network with the possibility of maintaining the maximum power point tracker (MPPT). The primary stage of the converter is made as a push-pull current source inverter topology with an additional switch, which is installed between the common point of the transformer's primary half-windings and the common point of the primary stage switches. The primary stage switches are made as a series connection of MOSFET transistors and Schottky diodes. The secondary stage has the traditional topology of a half-bridge voltage source inverter on MOSFET. A special switching algorithm of separated commutation is described, which provides non-dissipative snubber turn-on for of the current source inverter switches and their natural zero current turn-off switching (ZCS). The role of a snubber is performed by the leakage inductance of the transformer. For voltage source inverter switches, natural zero voltage switching (Zero Voltage Switching, ZVS) is provided. The role of non-dissipative capacitive switching snubbers may be performed by the MOSFET own output capacitance. The essence of this algorithm is to create a delay between the moment of forced switching on of the main key of the primary link and the moment of forced switching off of the transistor of the secondary link. There is also a small interval of energy return to the input source. Adjustment of the converter for the implementation of MPRT can be carried out by adjusting the ratio of the durations of the conduction state of the main and additional switches of the primary stage relative to the duration of the half-period of the frequency conversion. The types of switches were selected, static losses were estimated, simulation modeling was carried out in the MATLAB/Simulink environment, which confirmed the theoretical conclusions and the presence of soft switching modes.
ENTRE A FÉ E A EXPRESSÃO POLÍTICA. ETNOGRAFIA DAS INTERAÇÕES ENTRE PASTORES E FIÉIS EVANGÉLICOS DURANTE AS ELEIÇÕES DE 2022 NO RIO DE JANEIRO
Authors: BARROS MARGAUX DE
Published: September 2024

Resumo: Este artigo examina as interações entre pastores e evangélicos durante a campanha eleitoral de 2022 na periferia do Rio de Janeiro. Por meio de entrevistas e observações etnográficas, mostra-se como o pastor de uma pequena igreja evangélica de bairro introduz questões políticas nos cultos e tenta moldar as preferências eleitorais da congregação. Observa-se que o discurso político é limitado e regulado por preocupações econômicas e normas cerimoniais. Em seguida, examina-se como os fiéis e a equipe pastoral reagem à crescente politização dos sermões e tentam transmitir suas próprias representações políticas. Por fim, analisa-se como o apoio dado ao candidato Jair Bolsonaro gera conflito e dissensão entre a congregação, levando alguns deles a se distanciarem e a se retirarem temporariamente do culto.
Antimicrobial and antibiofilm activities of Inga cylindrica trypsin inhibitor
Authors: Pereira A. P. R. , Jacobowski A. C. , Sardi J. C. O. , Almeida C. V. , Almeida L. H. O. , Silva M. M. , Macedo M. L. R.
Published: September 2024

Abstract Inga cylindrica, a tropical fruit tree of the Fabaceae family (subfamily Mimosoideae), is native to South America. The seeds from this family are an essential source of trypsin inhibitors, which display promising bioactivity for increasing host defense against pathogens. The aim of the present study was to characterize the antimicrobial and antibiofilm activities of the trypsin inhibitor extracted from I. cylindrica seeds, ICTI. ICTI demonstrated antifungal activity with a minimum inhibitory concentration (MIC) of 32.11 μmol.L-1, and a minimum fungicidal concentration (MFC) of 32.1 μmol.L-1, against Cryptococcus gattii, Candida albicans, Candida glabrata and Candida guilliermondii. Combining ICTI with Amphotericin B had a significant synergistic effect, reducing the concentration of the antibiotic by 75% for C. albicans and 94% for C. gatti. The significant increase (16 x) in activity observed with ergosterol (1.01 mol.L-1) for C. albicans and C. gatti, and the lack of activity against bacterial strains, suggests that ICTI interferes with the integrity of the fungal cell membrane. Treatment with ICTI at 10 x MIC resulted in a 51% reduction in biofilm formation and a 56% decrease in mature biofilm colonies for C. albicans. Finally, ICTI displayed no toxicity in the in vivo Galleria mellonella model. Given its antifungal and antibiofilm properties, ICTI could be a promising candidate for the development of new antimicrobial drug prototypes.
Duas estratégias para a otimização do uso da vídeoanálise em atividades didáticas experimentais
Authors: Catelli Francisco , Thomazoni Júlia Giacomet , Giovannini Odilon
Published: September 2024

A vídeoanálise é um recurso experimental muito utilizado nas atividades experimentais ligadas ao ensino da física. A captura de posições e distâncias nos quadros de um vídeo é afetada pelas eventuais distorções de perspectiva resultantes do posicionamento da câmera (em geral a de um telefone celular) em relação ao plano no qual ocorre o movimento. O posicionamento dos marcadores sobre o objeto em movimento, por sua vez, depende bastante da nitidez das imagens. Neste trabalho, são discutidas estratégias para o posicionamento adequado da câmera, bem como a necessidade de uma iluminação adequada. No final é apresentado um exemplo no qual estes ajustes produzem resultados acurados.
The longitudinality of care from the perspective of Family Health users
Authors: Maciel Anna Maria Meyer , Lettiere-Viana Angelina , Mishima Silvana Martins , Fermino Tauani Zampieri , Matumoto Silvia
Published: September 2024

ABSTRACT Objective: To analyze longitudinality in the production of care in Family Health from the perspective of users. Method: Qualitative research carried out with 18 users of a family health unit in a municipality in the state of São Paulo. The data was produced through semi-structured interviews and the empirical material was analyzed by interpreting the meanings in the light of the theoretical framework of continuity of care and longitudinality. Results: 22 ideas were identified and grouped into three meanings: organization and operationalization of work in the family health unit, self-care and the health system. The first highlighted elements of organizational constraints, workforce, hard and soft technologies. The second direction pointed to the user’s co-responsibility for their health condition and lifestyle, making it possible to recognize longitudinality as: discontinuous or focused and continuous or extended. And in the third meaning, the understanding of the functioning of the three levels of care was presented with structural and technological demarcations. Conclusion: The users recognized potential and weaknesses in the three meanings referring to the constituent elements of the theoretical framework. Family Health is capable of offering continuous or extended longitudinality, even in a municipality with low coverage of the strategy. However, this scenario can weaken the process of developing the attribute from this perspective, as it limits access to other levels of care and compromises its structuring elements and dimensions and, consequently, the continuity of care.
Sociodemographic and occupational characteristics associated with burnout syndrome in healthcare workers post-COVID-19
Authors: Velasquez Muñoz Andrea Alejandra , San Martin Santibáñez Rocio Paulina , Contreras Muñoz María Paz , Vicuña Aguayo Eduardo Andrés
Published: September 2024

Abstract This study analyzed the relationship between sociodemographic and occupational characteristics and burnout syndrome among 379 healthcare workers in southern Chile in 2022, using sociodemographic and occupational questionnaires and the Maslach Burnout Inventory. The association between variables was assessed using the chi-squared test (χ2), and principal component analysis (PCA) was conducted. A burnout prevalence of 8.71% was found, with high levels of emotional exhaustion (41.7%) and low self-realization (40.6%). PCA showed that emotional exhaustion and depersonalization were associated with burnout, whereas self-realization was linked to the absence of this syndrome, suggesting it may be a protective factor. Contrary to expectations, low levels of burnout were observed post-pandemic. Associations were identified between burnout syndrome and factors such as the work environment, type of work, work shift, and caring for people at risk. Emotional exhaustion and lack of self-realization emerged as influential factors. These findings underscore the need for interventions aimed at improving working conditions and fostering psychological well-being in the healthcare sector.
La Verneda-Sant Martí Adult School: dream and science in education
Authors: Oliveira Cristiane Fontes de , Mello Roseli Rodrigues de , Marigo Adriana Fernandes Coimbra , Constantino Francisca de Lima , Braga Fabiana Marini
Published: September 2024

ABSTRACT Based on a longitudinal case study, the article aims to analyze the dynamics of classes, the didactic support material and the results of the literacy process of adults developed in a Spanish Freirian school that is a world reference both in adult education and in the participatory processes of learners. The data was analysed through the techniques of content analysis and communicative methodology, having as a theoretical basis the studies of dialogical learning. The researchers conclude that the processes carried out by the school promote strategies with potential for greater engagement of the pupils in school actions, expansion of learning and social transformations, on an individual and collective-community level. The relevance of the research is in presenting dialogical processes of learning and participation in an articulated manner, overcoming the opposition that is often made between dream and science in education.
Water regimes and hydrogel applied on bell pepper grown in a protected environment
Authors: Menezes Ademir Silva , Pinheiro Neto Luis Gonzaga , Bastos Edson Alves , Ramos Dânley Erlen de Oliveira , Viana Thales Vinícius de Araújo , Sousa Carlos Henrique Carvalho de , Façanha Rafaela Vieira , Lopes Francisca Gleiciane Nascimento
Published: September 2024

Abstract The objective of this work was to evaluate the effect of the application of different doses of hydrogel and irrigation levels on the morphophysiological and productive behavior of a bell pepper cultivar, in a protected environment. Four doses of hydrogel (0.0, 0.6, 1.2, and, 2.4 g per plant) and four irrigation levels (50, 75, 100, and, 125%) were used, on the basis of the daily evapotranspiration of a bell pepper crop grown in a sandy soil. Height, stem diameter, and leaf area were measured at 70 and 100 days. At the end of the experiment, bell pepper yield and water use efficiency were estimated. Hydrogel associated with irrigation increases leaf area, productivity, and irrigation-water use efficiency. The applied water deficit (132.8 and 199.26 mm), associated with the hydrogel doses, does not affect the plants morphologically.
Changes in the nutritional status of 'BRS Thap Maeo' banana induced by Banana streak virus
Authors: Moreira Adônis , Gasparotto Luadir , Pereira José Clério Rezende , Moraes Larissa Alexandra Cardoso
Published: September 2024

Abstract The objective of this work was to evaluate the effect of Banana streak virus (BSV) on the nutritional status and yield of 'BRS Thap Maeo' banana plants cultivated in the state of Amazonas, Brazil. Thirty-six plants were analyzed: 18 with and 18 without visible BSV symptoms. The infected plants showed nutritional disorders, with reduced foliar concentrations of nitrogen, phosphorus, potassium, and magnesium, as well as higher levels of calcium, zinc, iron, sulfur, boron, copper, and manganese. The banana plants with BSV symptoms present, in average, a 60% reduction in bunch weight.
Molybdenum and nickel foliar application on soybean yield and oil and protein contents
Authors: Moreira Adônis , Cardoso Bruna Miguel , Dameto Larissa Sartori , Delfim Jorge , Moraes Larissa Alexandra Cardoso , Lazarini Edson
Published: September 2024

Abstract The objective of this work was to evaluate the effect of the foliar application of molybdenum (Mo) and nickel (Ni) on the grain yield, yield components, and oil and protein contents in the grains of soybean cultivated under two edaphoclimatic conditions in Brazil. The following soybean genotypes were evaluated at the beginning of the R1-R2 growth stage: 'Brasmax Desafio RR', in the municipality of Londrina, in the state of Paraná; and 'TMG 7063 IPRO' and 'Brasmax Desafio RR', in the municipality of Selvíria, in the state of Mato Grosso do Sul. The treatments consisted in the application of four Mo rates (0, 400, 800, and 1,600 g ha-1) and three Ni rates (0, 60, and 120 g ha-1). The soybean genotypes exhibited varying responses to the two edaphoclimatic conditions. The foliar application of Mo is an effective strategy to increase the grain yield and protein content of 'TMG 7063 IPRO' e 'Brasmax Desafio RR'. However, with the application of 120 g ha-1 Ni, both genotypes show the worst performance for yield components and oil and protein contents. The 'Brasmax Desafio RR' genotype presents varied responses across different soil and climate conditions.
POST-OPERATIVE INFECTION IN THE CONTEXT OF ONCOLOGY PATIENTS WITH SPINE AFFECTION: A RETROSPECTIVE ANALYSIS
Authors: Bitencourt Junior Oswaldo Costa , Sanchez Fernando Barbosa , Coimbra Brian Guilherme Monteiro Marta , Prota Cristina , Belizário Juliana de Cassia , Sampaio Luciana Ribeiro , Teixeira William Gemio Jacobsen , Cristante Alexandre Fogaça , Kiyomoto Henry Dan
Published: September 2024

ABSTRACT Objective: To identify characteristics and associate the complications in cancer patients operated on by the Spine Group at the Cancer Institute of the State of São Paulo (ICESP) from January 2020 to December 2020. Methods: Retrospective analysis of medical records of patients operated on by the spine group. Results: Of the total of 62 cases, the majority, 69.4%, were residents of the state of São Paulo. There were 24.2% of smokers, of which 93.3% died. We identified that 48.4% had no family history of CA. It was identified that 62.9% received radiotherapy, and 75.8% were undergoing systemic treatment. There were three preoperative transfusions, 16 intraoperative transfusions, and five postoperative transfusions. We found an association between cases that required postoperative transfusion and cases of infection, p=0.019. The total number of postoperative infections was 9 cases (14.5%). Conclusions: Postoperative infections are undesirable events in the oncological context in the postoperative period and may be associated with the patient’s clinical conditions. Level of Evidence III; Retrospective Study.
Desvendando Respostas em de Crise: Um Retrato da Atenção Primária à Saúde Frente à COVID-19 em Lavras-MG
Authors: Chagas Alexandra Almeida Pinheiro , Caldeira Gatti Julie , Freitas Millena Vieira Simões de , Braz Mirian Silvia , Ferreira Raquel Aparecida , Barçante Joziana Muniz de Paiva
Published: September 2024

A COVID-19 é uma virose infecciosa de alta transmissibilidade. Visto que a Atenção Primária à Saúde (APS) é uma porta de entrada para o SUS, houve a necessidade de reorganização das unidades no período pandêmico. Mediante o fato, o presente estudo objetivou caracterizar a estrutura da APS, para entender como ocorreu tal reorganização no município de Lavras-MG. Foi realizado o mapeamento da rede de serviços da APS, um esclarecimento entre os registros de COVID-19 e a área de abrangência da Estratégia Saúde da Família (ESF). Além de entrevistas com peças-chave da APS para conhecer e entender como se deu o enfrentamento à pandemia. Elas foram gravadas, transcritas e comprovadas. A distribuição espacial dos casos de COVID-19 ocorreu de forma dispersa e as áreas de maior concentração dos casos foram cobertas pela ESF. Havia 17 equipes da ESF e cobertura de aproximadamente 60% da população total. As equipes se viram obrigadas a realizar reconfigurações importantes, abandonando desde alterações estruturais até revisões nos protocolos operacionais. O presente estudo reforça a necessidade de uma abordagem integral, interdisciplinar e ininterrupta para enfrentar a COVID-19, destacando que a APS se erige como um ambiente propício para a afirmação desses princípios quando inseridos na prática do cuidado à saúde.
FREEZING POINT AND GLASS TRANSITION TEMPERATURE OF DIGLYCEROL TETRANITRATE AND THE PRIMARY REACTIVITIES OF ITS PYROLANTS
Authors: Song Xiaolan , Wang Yi , Song Dan , Chen Kangyu , An Chongwei , Li Fengsheng
Published: September 2024

Diglyceryl tetranitrate (DGTN) is an excellent energetic plasticizer with four nitrate ester groups and an ether bond in its molecular structure, thus possessing high energy performance. Herein, the measured freezing point and glass transition temperature of DGTN were -52.7°C and -60.8°C, respectively, while the freezing point of NG was as high as 13°C. In addition, to explore the energetic properties of DGTN, it was mix with NC, AP, Al, and nitroamine explosive, and the pyrolants using DGTN as plasticizer were prepared. These pyrolants showed good thermal decomposition characteristics and combustion performance. DSC testing revealed that activation energy for thermal decomposition of
DGTN-based pyrolant was at the value of 137 kJ/mol. The combustion performance of DGTN-based pyrolant was tested using a high-speed camera, a high-sensitivity thermal infrared camera, and a combustion heat tester. The results disclosed that the DGTN-based pyrolants have high combustion pressure and high pressurization rate; the pyrolants also have high combustion temperature. Especially, the combustion heats of the pyrolants in excess pure oxygen are very high. In summary, DGTN and its pyrolants exhibited excellent energetic characteristics.
PHYSICS-INFORMED ENCODER-DECODER GATED RECURRENT NEURAL NETWORK FOR SOLVING TIME-DEPENDENT PDES
Authors: Long Jie , Khaliq A. Q. M. , Xu Y.
Published: September 2024

The ability of deep-learning approaches to approximate complex functions offers a promising alternative
for solving partial differential equations (PDEs). The methodology of incorporating the physics prior to the deep neural network can significantly reduce the requirement for labeled data. In this study, a novel physics-informed encoder-decoder gated recurrent units neural network is proposed to solve the time-dependent PDEs without using any observed data. The encoder is utilized to approximate the underlying patterns and structures of solutions over the entire spatial-temporal
domain. The approximated solution is processed by the decoder, which is the gated recurrent units
layer. We utilize the initial condition as the initial state of the gated recurrent units to retain critical
information in the hidden states. The boundary conditions are enforced in the final prediction to enhance the model's performance. Then, we incorporate physical laws into the neural network during the training process. The effectiveness of this algorithm is demonstrated by solving Burgers-Fisher and coupled two-dimensional burgers' equations. The ability to identify unknown parameters is demonstrated through the solution of inverse problems.
El extracto metanólico de Tillandsia recurvata reduce los niveles de glucosa, triglicéridos y colesterol en sangre
Authors: Garcia-Campoy Abraham H. , Perez Gutierrez Rosa M. , Garcia Báez Efrén V. , Muñiz-Ramírez Alethia
Published: September 2024

Background: Tillandsia recurvata collected in San Luis Potosí does not have studies focused on its use as an adjuvant in treating diabetes mellitus.
Questions and / or Hypotheses:  Will Tillandsia recurvata L. (Bromeliaceae) have antidiabetic activity in vitro and in vivo?  
Studied species: Tillandsia recurvata L. (Bromeliaceae)
Study site and dates: T. recurvata was collected in  Guadalcázar municipality, San Luis Potosí, México, in December 2021.
Methods: The antidiabetic potential of Tillandsia recurvata methanol extract (TRM) was evaluated using in vitro and in vivo models, and its secondary metabolite content was analyzed using Gas chromatography-mass spectrometry.
Results: Results demonstrate that extract reduces blood glucose, triglyceride, and cholesterol levels in vivo. In addition, in vitro tests showed that extract diminished the formation of advanced glycation end products, methylglyoxal concentrations, and glycosylated hemoglobin levels. Gas chromatography-mass spectrometry analysis identified several compounds in the extract, including 2-methylbenzaldehyde, 4-hydroxy-2-methylacetophenone, 3',5' dimethoxyacetophenone, pentanoic acid, palmitic acid, linoleic acid, phytol, margaric acid, oleamide, cis-11-eicosenamide, stearic acid, 13-docosenamide, (Z), campesterol, and β-sitosterol.
Conclusions:  These results highlight the potential of T. recurvata collected in San Luis Potosi as an adjuvant in treatment of diabetes mellitus.
Cestrum amithii (Solanaceae), nueva especie de San Luis Acatlán, Guerrero, México
Authors: Montero-Castro Juan Carlos , Vázquez-Rivera Paulina
Published: September 2024

Background: One specimen collected in Yoloxóchitl (San Luis Acatlán, Guerrero, Mexico) was initially reviewed by Michael Nee, who suggested that it could be a new species of the genus Cestrum, and commissioned to the first author to describe it.
Questions: Do Cestrum populations from San Luis Acatlán, Guerrero, correspond to a new species for science?
Studied species: Cestrum sp. nov.
Study site and dates: Yoloxóchitl, Municipality of San Luis Acatlán, Guerrero; 2023-2024.
Methods: The specialized bibliography on the genus Cestrum was examined, from which a list of species with similar morphology to the studied species was compiled, all of which were examined using high resolution digital photographs. A botanical exploration was carried out, locating three populations. A morphological analysis was conducted with the collected material.
Results: Cestrum amithii is defined as a new species for science. This new species presents many differences in terms of floral and foliar characters from the other species of the genus. The most outstanding is its spathaceous calyx, which is markedly asymmetrical and large, with evident ribs and two to three lobes. C. amithii is known only from Yoloxóchitl, Guerrero, where it grows in sub-deciduous tropical forest vegetation, at elevations of 530-630 m asl. It is associated with seasonal streams and creeks.
Conclusions: With this new discovery, the number of Cestrum species in the flora of Guerrero state increases to 16.
Intrasubject variability of acoustic absorbance in adults – pilot study
Authors: Grzesiuk Patrycja , Kochanek Krzysztof , Jędrzejczak Wiesław W.
Published: September 2024

Wprowadzenie

Tympanometria szerokopasmowa (ang. wideband tympanometry, WBT) to relatywnie nowa metoda badania ucha środkowego cechująca się większymi możliwościami badawczymi niż klasyczna tympanometria. Jednak do chwili obecnej nie ustalono zakresów wartości pomiarów, które pozwoliłyby jednoznacznie odróżniać normę od patologii. Dlatego też aby WBT mogło być efektywnie stosowane klinicznie, wymaga wciąż badań nad czynnikami, które mogą wpływać na dokładność tej metody. Celem niniejszej pracy było sprawdzenie powtarzalności pomiarów WBT.

Materiał i metody

Grupa badawcza składała się z 4 mężczyzn i 7 kobiet, w wieku 22–53 lata, niezgłaszających większych problemów ze słuchem. Wśród narzędzi badawczych znalazły się: kwestionariusz wywiadu oraz arkusz samooceny słuchu. Badanie właściwe przeprowadzono za pomocą sprzętu InteracousticTitan. U każdej osoby badanej wykonano 10 pomiarów w odstępie 7-dniowym.

Wyniki

Przebiegi wykresów absorbancji prezentowały dużą zmienność śród- jak i międzyosobniczą. Minimalny rozrzut wyników absorbancji wynosił około 0,06, a maksymalny sięgał około 0,16. Obserwując wyniki poszczególnych osób, można było zaobserwować, że u większości z nich najmniejszy rozrzut wyników absorbancji uzyskiwany był w zakresie niskich częstotliwości, a największy – w zakresie średnich i wysokich.

Wnioski

Dzięki uzyskanym wynikom można stwierdzić, że rozrzut wyników absorbancji jest zmienny w zależności od częstotliwości. Można także zauważyć zróżnicowanie międzyosobnicze.
Paramecium cultures for RNAi v1
Authors: Jenkins Ben
Published: September 2024

Filtering and preparing P. bursaria cultures for downstream RNAi
Prevailing Issues and Actions in Urban Best Practices Across Latin America and the Caribbean
Authors: Capra-Ribeiro Fabio
Published: September 2024

This research examines urban best practices (BPs) across Latin America and the Caribbean to illuminate the prevalent issues and actions associated with these locally implemented initiatives. An analysis of 45 BPs from the UN-Habitat repository was conducted using both quantitative and qualitative methods, organized into three phases. The first phase focused on collecting data such as BP sources, countries of origin, and years of implementation. The second phase identified common problems and actions within the BPs. The third phase involved a cross-sectional analysis to identify significant patterns and trends. The study found that many BPs originated from the Dubai International Award for Best Practices and the Guangzhou International Award for Urban Innovation, with a notable dominance of contributions from Brazil, followed by Argentina and Mexico, while other countries in the region had minimal or no representation. The results revealed shared challenges and commonly adopted actions across diverse BPs, transcending characteristics, locations, and implementation years. The most common issues included financial constraints, bureaucratic complexities, and deficient infrastructure, while active community engagement, collaboration with various stakeholders, and garnering political support were the most recurrent actions. This research contributes novel insights to the field by systematically analyzing real-world case studies in the region, enhancing understanding of the transferability of these practices. It also identifies key similarities that will aid policymakers and practitioners in preparing and optimizing future initiatives for greater success.
Omics technologies in diagnosis and treatment of soft tissue sarcomas
Authors: Afonina T. S. , Bukharov A. V. , Fedenko A. A. , Derzhavin V. A. , Aliev M. D.
Published: September 2024

Currently, stratification of recurrence risk and prognosis of 5-year survival of patients with soft tissue sarcomas are primarily based on histological tumor classification. Drawing from these data, international oncological societies have proposed a hypothesis about development of gene expression profiling and molecular and genetic diagnosis technologies which will allow to more accurately assess risks of soft tissue sarcoma development and select individual drug treatment.
Soft tissue sarcomas associated with neurofibromatosis: treatment experience
Authors: Zubarev A. L. , Kurilchik A. A. , Ivanov V. E. , Starodubtsev A. L. , Khanina2 M. K.
Published: September 2024

Soft tissue sarcomas are a rare and heterogeneous group of solid tumors originating from the mesenchyme and accounting for only 1 % of all malignant neoplasms in adults. The modern clinical and morphological World Health Organization of soft tissue sarcomas classification includes more than 100 forms of these tumors. Neurofibromatosis is a group of hereditary, autosomal dominant diseases characterized by the development of multiple tumor formations, often benign. Currently, there are 3 types: neutrophibromatosis type I, neurofibromatosis type II and schwannomatosis. The estimated risk of developing sarcoma in patients with neurofibromatosis type 1 at age 30 years is 25.1 %, and by age 50 years it is 38.8 %. Treatment of soft tissue sarcomas associated with neurofibromatosis fully complies with the standard recommendations of National Comprehensive Cancer Network, NCCN (NCCN), American Society of Clinical Oncology (ASCO), European Society for Medical Oncology (ESMO) and RUSSCO and does not have its own peculiarities. Over the past 15 years, at the A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, more than 190 patients with locally advanced, high-grade soft tissue sarcomas have been treated, including five patients with sarcomas associated with neurofibromatosis. The article presents clinical cases of treatment of soft tissue sarcomas associated with neurofibromatosis.
Angiosarcoma of the breast gland: molecular genetic profile, diagnosis and treatment
Authors: Lyubchenko L. N. , Saribekyan E. K. , Bosieva A. R. , Zikiryakhodzhaev A. D. , Buchkin G. L. , Zamaldinov N. D. , Fedenko A. A.
Published: September 2024

Angiosarcoma is a rare, aggressive tumor arising from the endothelial cells of blood vessels that can affect internal organs, but the most common location is the skin. The article presents current data on the molecular genetic profile, diagnosis and treatment of primary and secondary angiosarcomas of the breast. A search for relevant sources was carried out in the PubMed, Cochrane Library and eLibrary systems, publications from 2012 to 2023 were examined, 29 of which were used to write this review.no standard treatment guidelines, and the optimal approach remains surgical resection to achieve negative resection margins. The role of neoadjuvant, adjuvant chemotherapy and radiotherapy remains controversial.
. Prevalence and prognostic mutation V600E in the BRAF gene in stage I cutaneous melanoma
Authors: Titov K. S. , Sorokina M. V. , Grekov D. N. , Lebedev S. S.
Published: September 2024

Introduction. Melanoma is one of the most aggressive skin tumors, which occurs against the background of malignant transformation and proliferation of melanocytes. Risk factors for the development of cutaneous melanoma are solar radiation and duration of exposure, old age, individual patient characteristics (light skin, a large number of nevi, including atypical ones, family history) and others. Research in recent years shows that this disease is associated with a number of genetic changes, both congenital and acquired.

Aim. To study the frequency of occurrence and prognostic significance of the V600E mutation in the BRAF gene in stage I skin melanoma.

Materials and methods. The study was retrospective in nature and included 88 patients with stage I cutaneous melanoma (pT1–2aN0M0). All patients underwent a sentinel lymph node biopsy and no metastases were detected in it (pN0). All patients underwent molecular genetic analysis of the tumor to identify the V600E mutation in the BRAF gene with further assessment of the effect on the progression of early skin melanoma in cases of its detection.

Results. The median follow-up time for patients was 32.5 (12–214) months. In 25 (28.4 %) patients of the total sample, the V600E mutation in the BRAF gene was detected. Melanoma progression during follow-up occurred in 23.9 % of patients: 44 % with the V600E mutation in the BRAF gene and 15.9 % without it (p = 0.012). In patients with this mutation, regional metastasis was more often observed, with a predominant localization of distant metastases in the bones. Survival rates were significantly higher in patients without a mutation in the BRAF gene: 1-year disease-free survival of patients without a mutation in this gene was 95 %, 3-year – 87%, 5-year – 65 %, in patients with this mutation – 84, 57 and 37 % respectively. According to the results of Cox regression analysis, in the presence of a mutation in the BRAF gene, there was an increase in the risk of progression to stage I cutaneous melanoma by 2.973 times (p = 0.016).

Conclusion. The V600E mutation in the BRAF gene occurs in 28.4 % of patients with stage I cutaneous melanoma and is an unfavorable prognostic factor for disease progression.
Robot-assisted surgery for rectal cancer in patients after neoadjuvant chemoradiotherapy Immediate results
Authors: Moiseev M. E. , Kotiv V. N. , Gladyshev D. V. , Vetoshkin V. A. , Kovalenko S. A. , Murashko R. A. , Khondziya S. Z. , Svitich V. Yu. , Gnedash S. S. , Butorina A. S. , Skobaro A. S.
Published: September 2024

Introduction. The benefits of robotic surgery for rectal cancer remain controversial. Only a few studies have evaluated the safety and feasibility of robot-assisted surgery after neoadjuvant chemoradiotherapy.

Aim. Our study aimed to compare the short-term outcomes of robotic and traditional laparoscopic surgery after neoadjuvant chemoradiotherapy for rectal cancer.

Materials and methods. This retrospective study was based on the analysis of 210 medical records of patients with rectal tumors who underwent robot-assisted and laparoscopic-assisted surgeries after neoadjuvant chemoradiotherapy from 2015 to 2021.

Results. There was no significant difference in short-term outcomes such as operation time, conversion rate, anastomotic leakage, and quality of circular resection margin. However, a significant difference was noted in the quality of total mesorectal excision. Grade 3 quality in the R group was 93.9 %, while in the L group it was 74.07 % (Odds Ratio (OR) 2.335; 95 % Confidence Interval (CI) 1.107–4.925). A statistically significant difference was also found in the rate of performing sphincter-preserving procedures, with 12.2 % in the R group and 50 % in the L group (OR 0.139; 95 % CI 0.066–0.293).

Conclusion. The advantages of the robotic surgical system in the surgical treatment of rectal cancer in patients after neoadjuvant chemoradiotherapy improve clinical outcomes, primarily reflected in the rate of sphincter-preserving operations. Additionally, it provides a trend towards achieving more oncologically adequate tumor removal compared to laparoscopic procedures.