bluuebunny/crossref_metadata_2025 huggingface dataset:
Mindfulness: Why it may work and why it is sure to succeed
Authors: Errasti-Pérez José , Al-Halabí Susana , López-Navarro Emilio , Pérez-Álvarez Marino
Published: April 2022

Mindfulness has gone beyond clinical applications and is beginning to be enthusiastically applied in schools, sport, and business settings. It seems to be a type of intervention that, while probably effective, has a small effect size, which calls for rigorous research. Understanding the psychological processes involved in mindfulness is essential in order to achieve a more realistic picture of its usefulness for some behavioral disorders. How can we explain the extraordinary success of mindfulness in western societies, both in academia and in popular culture? We present three behavioral principles and ideological reasons for applying mindfulness. Nowadays, mindfulness is framed not by mystical existentialism or contextual behaviorism, but by positive psychology and its neoliberal agenda.
USE OF MOBILE APPLICATIONS TO IDENTIFY PLANTS
Authors: Bilyk Zh. I. , Shapovalov Ye. B. , Shapovalov V. B.
Published: April 2022

One of the main principles of effective learning is the principle of «corresponding to nature», ie providing the environment in which the child learns should be familiar to him. For the modern child, the environment of gadgets has become a natural environment. That is why the use of mobile applications is a very promising method of learning. Software that can be used during the learning process in the application of STEM technology can be divided into desktop applications, mobile applications, and web-oriented technologies. The paper is devoted to research mobile applications used during the STEM-classes and can be used to identify plants. There are 10 mobile applications that are plant identifiers worldwide. These applications can be classified into three groups, such as plant identifiers that can analyze photos, plant classification provides the possibility to identify plants manually, plants-care apps that remind water of the plant, or change the soil. The following mobile applications were analysed: Flora Incognita, PlantNet, PlantSnap, PictureThis, LeafSnap, Seek, PlantNet regarding ease of use and identification accuracy. PlantNet is the easiest app to install. Also, pretty easy to install are LeafSnap and Flora Incognita. Apps LeafSnap, Flora Incognita, and Seek to have the simplest interface. PlantSnap, PictureThis, and PlantNet are characterized by the most uncomfortable process of identification which can be complicated for teachers. Seek is the interesting application, which provides detailed instructions for students on research. This application also has tools to encourage students and offers participation in international research projects. It has been proven that Flora Incognita and PlantNet have the most user friendly and most informative interface of plant identification programs. Flora Incognita provides correct identification of 71% of plants compared to 55% provided by PlantNet. For comparison, this figure for Google Lens is 92.6%. However, they were significantly less accurate than the Google Lens results. Therefore, Google Lens is the most recommended app to use. Talking to account, results of usability analysis, and quality of analysis, for those students and teachers who do not like Google Lens app, it is possible to use Flora Incognita, but PlantNet can’t be recommended to use due low accuracy which may provide up to half of incorrect analysing results. Although Flora Incognita identifies species of local (aboriginal) flora with higher accuracy. A detailed experimental study of Google Lens and its comparison with other mobile applications allow us to recommend Google Lens for use in the lessons when applying the STEM approach.
Pengaruh Persepsi dan Kualitas Pelayanan terhadap Kepuasan Pasca Pembelian Pengguna Aplikasi Online Shop
Authors: Anasrullah Muhammad , Sri W. H Maria Agatha , Nurhana Farida
Published: April 2022

This study aims to determine: (1) The Effect of Perception on Post-Purchase Satisfaction of Online Shop Application Users, (2) The Effect of Service Quality on Post-Purchase Satisfaction of Online Shop Application Users, (3) The Effect of Perception and Service Quality on Post-Purchase Satisfaction of Online Application Users. Shop (At Bhinneka PGRI University Students). The type of research used in this research is a non-experimental quantitative regression research. The population in this study were students of the Bhinneka PGRI University with a total of 1.110 students. The sampling technique used is probability sampling method with simple random sampling with a total sample of 92 students. The data analysis technique used is simple linear regression, multiple linear regression, t test and F test. The results of this study indicate that there is a positive effect of Perception on Post Purchase Satisfaction. There is a positive effect of Service Quality on Post-Purchase Satisfaction While the results of the F test show that there is a simultaneous influence of Perception and Service Quality on Post-purchase Satisfaction.

Keywords : Perception, Service Quality, Post-Purchase Satisfaction.
Faktor-Faktor yang Mempengaruhi Kepuasan Pasien pada Puskesmas Suko Kecamatan Maron Kabupaten Probolinggo
Authors: Pujiastuti Agustina , Rahajeng Yekti , Arifin Sanol Nur
Published: April 2022

Patient satisfaction is the main goal of the puskesmas. The purpose of this study was to examine the effect of both simultaneously and partially the quality of service and trust on patient satisfaction and to examine the dominant between service quality and trust on patient satisfaction. The object of research is at the Suko Public Health Center, Maron District, Probolinggo Regency. The research method uses a descriptive approach causal associative with a sample of 88 respondents, the method of collecting data using a questionnaire with a technique using incidental sampling. The analysis test with the validity test shows that all statement items are valid, namely above 0.205, the reliability test shows reliable results that are above 0.60., the classical assumption test, the normality test, shows the data is normally distributed, the multicollinearity test shows that the independent variable (X) and the dependent variable (Y) are not present. correlation between independent variables or regression models independent of multicollinearity, heteroscedasticity test showed no heteroscedasticity, autocorrelation test showed no autocorrelation. The F test shows that the independent variables have a simultaneous effect on satisfaction (Y) with a value of Fcount > Ftable (37.426 > 3.10) (sig. 0.000 < 0.05). The t test shows that the service quality variable (X1) has a partial effect on satisfaction (Y) with tcount > ttable (2,228>1,663) (sig. 0.000 0.05). And the trust variable (X2) has a partial effect on satisfaction (Y) with a value of tcount ttable (4.032 > 1.663) (sig. 0.000 0.05). Trust has a dominant effect on patient satisfaction.
KOVİD-19 SALGINI NEDENİYLE ÖRGÜN EĞİTİMDEN UZAKTAN EĞİTİME GEÇİLMESİNE YÖNELİK ÜNİVERSİTE ÖĞRENCİLERİNİN GÖRÜŞLERİ
Authors: NAKİBOĞLU Aslıhan , IŞIK Sevgül
Published: April 2022

Kovid-19 salgını nedeniyle örgün eğitimden uzaktan eğitime geçilmesine yönelik üniversite öğrencilerinin görüşlerini belirlemektir. Amaç doğrultusunda araştırmacılar tarafından oluşturulan veri toplama aracı, Niğde Ömer Halisdemir Üniversitesi 04.5.2020 tarihli ve 19680 sayılı etik kurul izni ile 5 Mayıs 2020 ile 15 Mayıs 2020 tarihleri arasında Niğde Ömer Halisdemir Üniversitesi’nde eğitim gören 662 öğrenciye online olarak uygulanmıştır. Elde edilen veriler bilgisayar ortamında SPSS 22.0 istatistik programı aracılığıyla analiz edilmiştir. Araştırma sonucunda; üniversite öğrencileri Kovid-19 sürecinde verilen uzaktan eğitimin etkinliğine ilişkin yüksek düzeyde olumsuz görüşler içerisinde oldukları, uzaktan eğitimin etkinliğinde hocaların ve materyallerin yüksek düzeyde etkili olduğu sonuçlarına ulaşılmıştır
Similar shells in different seas: the case of Atlantic Brachystomia carrozzai (van Aartsen, 1987) and two allied Mediterranean species (Gastropoda: Pyramidellidae)
Authors: Nofroni Italo , Renda Walter , Vannozzi Angelo
Published: April 2022

The comparison of shells of Brachystomia carrozzai (van Aartsen, 1987) of Atlantic and Mediterranean origin allowed us to detect slight but constant morphological differences. In particular, Mediterranean specimens, here attributed to Brachystomia pizzinii n. sp., show, with respect to B. carrozzai, a more protruding and widely umbilicated protoconch, and a teleoconch with more convex whorls and clear suture. A further species with distribution limited to the waters of southern Spain, in the literature attributed to B. carrozzai as well, is described here as Brachystomia hispanica n. sp. The latter is distinguished from both B. carrozzai and B. pizzinii due to its small size and broader profile. Further, Brachystomia sorianoi (Peñas & Rolán, 2006) is reported for the first time from the Bay of Algeciras.
Interaction of endodontic irrigants
Authors: Valsan Shrenik , Antony S. Delphine Priscilla
Published: April 2022

Root canal therapy is to eliminate or at least reduce the number of microorganisms and remove inflamed or necrotic pulpal tissue. Root canal cleaning and disinfection during chemomechanical preparation relies heavily on irrigants because of the anatomic complexities of the pulp canal system.Although endodontic irrigants have been well characterized individually, combinations of the materials are not well understood.To know the interactions of different irrigants this review throws more light in depth to understand the interactions of irritants better.
Awareness and knowledge on biomedical waste disposal of dental materials among dental students
Authors: Harini P , Sowmya K
Published: April 2022

Introduction:  Management of waste generated from the medical sector is a challenging task and it is a critical issue because it acts as a hazard for human health as well as the environment. The waste generated from dental clinics are sharps, glasswares, metallic implants, blood, mercury, lead, biodegradable wastes, non biodegradable wastes and chemical wastes. It is important to segregate and transport these wastes using the proper guidelines. Aim: To assess the knowledge, attitude and practice of biomedical waste disposal among dental students. Materials and methods: Self administrated questionnaire was designed and distributed through an online google forms link. The Study population included 100 dental undergraduate students belonging to the age group of 18 to 24 years. The participants were explained about the purpose of the study in detail. The questions were carefully studied and the corresponding answers were marked by the participants. The data were collected and statistically analysed using SPSS software version 22.0. Chi- Square analysis was performed and p<0.05 was considered as statistically significant. Results: From the obtained data it was concluded that 87 % of the people were aware of biomedical waste and the methods and techniques to handle the biomedical waste.
Radiographic analysis of interorifice distance and canal configuration in mesial roots of mandibular first molars
Authors: Arun Nishitha , Pradeep S
Published: April 2022

Introduction: The Middle Mesial Canal (MMC) is an additional root canal that can be present in the mandibular molars of some patients with high chances of being missed. The aim of this study is to determine the inter orifice distance between Messiobuccal (MB) and Mesiolingual (ML) canal orifice and its association with the presence or absence of MMC using CBCT to help the operator clinically in identifying the presence of MMC. Methods: 50 CBCT samples consisting of 100 permanent mandibular first molar teeth were analysed. The distance between the mesiobuccal and mesiolingual orifice was recorded. Statistical Analysis such Independent T test and Pearson correlation were used to determine the association between MB and ML interorifice distance and presence of MMC and variation in the prevalence of MMC among male and female and different age groups. Results: The mean distance between MB and ML canal orifice was 3.19 ± 0.42mm, in the presence and absence of MMC the mean distance was 3.66±0.24mm and 3.07±0.38 mm respectively. The mean inter orifice distance in males was 3.29 ± 0.38 mm and in females was 3.08 ± 0.45 mm.
Evaluation of lipid profile and glycated haemoglobin in type 2 diabetic patients
Authors: Kumari Minakshi , Kumar Vinod , Verma Sunil Kumar , Mahli Rajiv Kumar
Published: April 2022

Background: Type 2 diabetes mellitus (T2DM) is a rapidly growing public health problem with significant implications for human health, living standards, the economy, and health-care systems around the world. Diabetic dyslipidemia is a risk factor for macrovascular (stroke, peripheral vascular disease, and coronary artery disease [CAD]) and microvascular (nephropathy, neuropathy, and retinopathy) disorders in T2DM patients. The level of circulating HbA1C is considered the gold standard of glycemic management, and it must be maintained in order to avoid T2DM problems. Aim : To investigate the association between glycated hemoglobin (HbA1C) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) Methods and Materials: Between January 2021 to December 2021 researchers at the SNMMC, Dhanbad, Jharkhand, conducted a retrospective cross-sectional study. The study included 200 T2DM patients (138 females and 62 males), and the data was gathered through a review of the patients' computerised profiles. The electronic file system also contained biochemical data such as fasting plasma glucose (FPG), HbA1C, and lipid profile, as well as the patient's age, BMI, and gender. Only patients who saw their doctor on a regular basis and whose electronic records were complete were eligible.
Comparison between local infiltration and intramuscular dexamethasone in surgical extraction of molar teeth
Authors: Talwar Anish , Kachhwaha Khushboo , Rehman Ahad , Sharma Monika
Published: April 2022

Background: A tooth extraction is a procedure to remove a tooth from the bony socket. It is usually done by a general dentist, oral surgeon ect. Most common cause of tooth extraction is badly decayed tooth, periodontitis, impaction. The extraction of impacted third molars is one of the most common operative procedure in oral surgery. The surgical removal of impacted third molars involves trauma to the soft and bony tissue that can result in considerable pain, swelling and trismus Corticosteroids such as dexamethasone may inhibit the inflammatory sequelae after third molar surgery. Materials and methods: The study was conducted on total of 30 subjects, with age group above 18 years. The patients were divided into two groups. Each group contained 15 subjects, group A subjects received local infiltration of dexamethasone 4 mg near the surgical site on buccal vestibule and group B subjects received intramuscular dexamethasone 4 mg in deltoid muscle before operation. Results: The results obtained show that submucosal dexamethasone is an effective alternative to dexamethasone given systemically. Conclusion: The submucosal dexamethasone associate with a significant reduction in swelling on 1-2days. This study has shown that a dexamethasone injected submucosally is better than intramuscularly in third molar surgery.
Attitudes towards and the confidence in acceptance of telemedicine among the people in Sabah, Malaysia
Authors: Manzoor Maneesha , Maziz Mohammad Nazmul Hasan , Subrimanyan Vetriselvan , Shirin Lubna , Doustjalali Saeid Reza , Sabet Negar Shafiei , Kabir Mohammed Shahjahan , Mathialagan Amuthaganesh
Published: April 2022

The access to healthcare in rural areas is difficult and telemedicine could be a promising solution to this problem if it is accepted by the population. The aim of this study was to assess different attitudes towards telemedicine, the level of confidence and acceptance of telemedicine among rural populations in Sabah. A questionnaire based on the Technology Acceptance Model (TAM) framework and other validated studies were developed to achieve the data for this study. The questionnaire was distributed to the residents of Penampang and Putatan in Sabah. The questions were scored using a five-level Likert scale and the level of confidence was rated from 0 to 100%. A high mean score of attitudes towards use and a moderate score of confidence was observed in the findings, indicating positive attitude towards telemedicine and reasonable level of confidence in using telemedicine services for their healthcare needs. Findings in this study revealed a high level of acceptance among the respondents, which was found to be generally consistent with previous telemedicine studies.
Identification of positive psychological practices in academics when learning is disturbed by the COVID-19 pandemic
Authors: Nugroho Budi Sulistiyo , Anaconda Bangkara B.M.A.S. , Fatmawati Endang , Maulani Ulfa , Aisha Hanifa
Published: April 2022

Positive thinking in psychology and learning is critical when various crises disrupt learning conditions. The author believes that people still have to be positive with the best practices to overcome all difficulties such as those experienced during the Pandemic. For this reason, we have collected several data in the form of scientific evidence from field studies of various experts and expertise, which we believe have provided support in answering the problems of this study. As for before we conclude, we have answered a series of questions using a phenomenological approach, namely an effort to collect as much data as possible and then analyze it to get one answer that is nominal data. Our strategy involves a data coding system, analyzing the data in-depth, evaluating and interpreting, and getting an understanding that becomes the conclusions and findings of a valid and reliable study. We then discuss the study results by considering various aspects of the context and content of this research. Finally, we can conclude that positive practical psychology has overcome problems in education, especially when the Pandemic hit the world. Experts have proved that education continues with all the technicalities and solutions through repressive best practices carried out.
Place de la compression médicale dans le traitement de la maladie thrombo-embolique veineuse
Authors: Didier RASTEL
Published: April 2022

Le traitement de la maladie thrombo-embolique veineuse est dominé par les stratégies pharmacologiques. Lacompression médicale fait l’objet, dans la vraie vie, d’unegrande laxité vis-à-vis des recommandations notammenten terme de pression prescrite aux patients. Si la place dela compression dans la prévention de la thrombose veineuseprofonde est actuellement réduite elle reste indispensableà la prise en charge de la pathologie à sa phase aiguë ainsique pour la prévention et le traitement de la morbidité postthrombotique. Les études apportent des indices importantspour un début de traitement par compression le plus précocepossible en phase aiguë de la thrombose veineuse.
SOMMAIRE
Authors: ESKA EDITION
Published: April 2022

sommaire
La Pharmacologie des AOD
Authors: A. EKOU
Published: April 2022

es AOD et les AVK ont des profils pharmacodynamiqueet pharmacocinétique radicalement différents. Les voiesenzymatiques empruntées, le mode d’action, l’éliminationhépatique et rénale sont singulières. Cette nouvelle génération d’anticoagulants oraux ne constitue pas une simpleclasse thérapeutique mais chaque représentant a sespropres caractéristiques.
AOD et fibrillation atriale
Authors: A. EKOU
Published: April 2022

Les antagonistes de la vitamine K (AVK) ont été lespiliers du traitement anticoagulant depuis plus d’un demisiècle.Les AVK sont principalement utilisés pour la préventiondes Accidents Vasculaires Cérébraux et des embolies systémiques chez les patients atteints de fibrillation atriale(FA). L’avènement des Anticoagulants Oraux Directs (AOD)avec quatre nouveaux agents - les inhibiteurs directs dufacteur Xa (apixaban, edoxaban et rivaroxaban) et l’inhibiteur direct de la thrombine (dabigatran) ont été approuvéspour cette indication.Compte-tenu des nombreuses limites des AVK, tellesque les interférences alimentaires, les interactions médicamenteuses et les préoccupations concernant les complications hémorragiques, l’attractivité des AOD est fondéeet de plus en plus reconnue
AOD et gestion des actes invasifs et/ou des hémorragies
Authors: A. EKOU
Published: April 2022

Depuis leur mise sur le marché, il y a plus de huit ans,l’experience et les données concernant les patients traitéspar anticoagulants oraux directs (AOD) et bénéficiant d’ungeste invasif programmé ou d’une prise en charge enurgence se sont particulièrement enrichies. Dans le mêmetemps, une augmentation du risque hémorragique lors dela réalisation de relais anticoagulants (bridging) péri-opératoires a été rapportée sans réduction manifeste durisque thrombotique. Le relais par anticoagulant parentéral n’est plus indiqué. Ces données nouvelles conduisent aadapter les propositions émises par les sociétés savanteset les groupes d’experts que nous aborderons dans cetarticle.
Un programme de remise en forme personnalisé
Authors: J. LONSDORFER  , Th. VOGEL  , P.H. BRECHAT  , J.-Ph. BRETTES
Published: April 2022

La pratique d’une activité physique régulière estrecommandée à tout âge et ses bienfaits sont reconnus tant en prévention primaire que pour réduiredes handicaps secondaires. Pourtant la grandediversité des méthodes rebute souvent le prescripteur et le destinataire, et déçoit aussi par le manquede résultats bien objectivables surtout chez lesenior. Nous présentons ci-après l’organisationd’une Consultation de l’Aptitude Physique duSenior (CAPS) conduisant à proposer une méthodede remise en forme : le PEP’C, un Programmed’Entrainement Personnalisé sur ergoCycle qui en2 mois améliore de +30%, au minimum,l’Endurance de la personne ! L’efficacité du PEP’Couvre de grandes perspectives tant comme adjuvant thérapeutique (cancer) que pour les incitationsde prévention en santé publique.
En finir avec la dictature de l’étude Women’s Health Initiative (WHI)
Authors: Henri ROZENBAUM
Published: April 2022

Depuis la publication en 2002 des premiers résultatsde l’étude Women’s Health Initiative (WHI) montrantune augmentation du risque de cancer du sein et desaccidents vasculaires, tout au moins dans le bras estrogènes + progestatifs, un certain nombre de publications, certaines provenant de l’étude WHI elle-même,ont permis de clarifier la situation.Le traitement hormonal substitutif (THS) n’augmente pas le risque cardio-vasculaire lorsqu’il estprescrit avant 60 ans ou à peu de distance de la ménopause. Il pourrait même induire un effet protecteur.En ce qui concerne le risque de cancer du sein, oninsiste de plus en plus sur le rôle néfaste de certainsprogestatifs, dont l’acétate de médroxyprogestéroneutilisé dans l’étude WHI.Un consensus se dessine pour prescrire des posologiesréduites, préférer des estrogènes par voie cutanée chezles femmes à risque vasculaire, de thrombose notamment, pour préférer la progestérone ou la dydrogestérone lorsqu’un progestatif est nécessaire.Enfin, il n’existe pas de limitation à la durée d’unTHS à condition d’informer les patientes et de procéder à des réévaluations périodiques.
Place de l’exercice physique dans l’optimisation du vieillissement
Authors: Pr F. PIETTE  , Dr A.S. REBILLAT
Published: April 2022

Le concept de « Bien Vieillir » est diversement ressenti par chacun et repose en proportions variablessur 3 notions : de durée, de qualité de vie et de coûtacceptable par la société. L’exercice physique régulier tient une place très importante sans doute à tousles âges mais en particulier dans la deuxième moitiéde la vie, réduisant la mortalité cardio-vasculaire deshommes notamment et le risque ultérieur de perted’autonomie motrice chez les femmes. Son rôle estparticulièrement net sur l’amélioration de la qualitéde vie au travers de la diminution de la dépression etde l’amélioration du sommeil. Il est bien établi aussidans la réduction des symptômes de l’arthrose. Il estplus modeste, voire contestable dans l’améliorationde la mémoire. Inséré dans un programme complexe avec des incitations répétées et de l’éducationthérapeutique, il réduit significativement le risqued’entrée en maison de retraite et d’hospitalisationsitératives. Un effort collectif est nécessaire pour lapromotion de l’exercice physique : meilleure formation des professionnels de santé, médiatisation, meilleure accessibilité notamment pour les personnesâgées fragiles
Anatomie pathologique du placenta de prééclampsie
Authors: Arnaud UGUEN  , Pascale MARCORELLES
Published: April 2022

L’examen placentaire apporte des renseignementsdans le bilan d’une grossesse marquée par la prééclampsie. Le placenta se caractérise par des lésionsmacroscopiques et microscopiques d’autant plusmarquées que la prééclampsie est de début précoceet est sévère. Quelques travaux récents ont soulignés outre l’intérêt du poids placentaire, l’intérêt dela forme régulière ou non du disque placentairecomme argument diagnostique envers cette pathologie par défaut d’implantation. Les différenteslésions placentaires macroscopiques et microscopiques qui peuvent être rencontrées sont définies etleur impact diagnostique est discuté. Enfin, il estimportant de souligner le caractère indispensabledes renseignements cliniques pour pouvoir interpréter l’aspect du placenta.
L’endothélium vasculaire dans le syndrome prééclamptique
Authors: Rosamaria CALICCHIO  , Daniel VAIMAN  , Francisco MIRALLES
Published: April 2022

La prééclampsie est une maladie de la grossessecaractérisée par une hypertension et une protéinurie maternelles. Cette pathologie demeure unecause majeure de mortalité et de morbidité maternelle et fœtale. Bien que la physiopathologie decette maladie ne soit pas totalement élucidée, il estétabli qu’au cours de la grossesse le placenta prééclamptique libère dans la circulation maternelle desfacteurs qui finissent par déclencher une dysfonction endothéliale systémique. Nous examinons iciles principales études montrant le rôle central del’endothélium dans le développement du syndromematernel de la prééclampsie. Nous décrivons defaçon approfondie des récentes études transcriptomiques décrivant les modifications subies par lescellules endothéliales après exposition au plasmaprééclamptique. Le plasma prééclamptiquecontient des facteurs capables d’agir directementsur l’endothélium vasculaire et de modifier l’expression de gènes impliqués dans des fonctionsessentielles telles que la vasomotricité, le stress oxydatif, l’apoptose et la prolifération cellulaire. Nousterminons cette revue en rapportant des observations reliant la dysfonction endothéliale survenuelors de la prééclampsie à un risque accru de pathologie cardiovasculaire sur le long terme. En conclusion, la caractérisation des modifications subies parl’endothélium vasculaire au cours de la prééclampsie devrait permettre d’orienter la recherche denouveaux outils diagnostiques et thérapeutiquesafin de mieux traiter la maladie et ses séquelles.
Un syndrome de type prééclampsie sévère induit chez la souris
Authors: Ludivine DORIDOT  , Bruno PASSET  , Céline MÉHATS  , Sandrine BARBAUX  , Jean-Luc VILOTTE  , Daniel VAIMAN
Published: April 2022

STOX1, un gène codant un facteur de transcription, a été lié à la prééclampsie, une pathologierépandue et spécifiquement humaine de la grossesse caractérisée par une hypertension et une protéinurie gestationnelles, et responsable de mortalitéet de morbidité maternelles et fœtales. Cette étudevise à mieux comprendre le rôle de STOX1 in vivo.Pour étudier son implication dans la pathologie,nous avons créé des souris transgéniques surexprimant le STOX1 humain. Des souris femellescontrôles ont été croisées avec des mâles transgéniques afin de limiter l’expression du transgène àl’unité fœto-placentaire et empêcher ainsi un effetdirect du transgène sur l’organisme maternel (reinet endothélium notamment). Ces souris contrôlescroisées avec des mâles transgéniques développentune hypertension et une protéinurie gestationnelles. L’hypertension est aussi élevé que celleobservée chez des patientes atteintes de prééclampsie sévère. Les reins de ces souris ont des anomaliesqui rappellent la pathologie humaine, avec desdépôts de fibrine. Enfin, nous avons testé un traitement : l’aspirine à faible dose qui est efficace pourempêcher l’hypertension et limite les altérationsrénales et la protéinurie. Nous avons obtenu unmodèle unique pour étudier la prééclampsiesévère, qui indique sans aucun doute un rôle clé deSTOX1 dans la physiopathologie. Cet outil serautile pour trouver de nouvelles voies qui pourraientêtre impliquées dans la physiopathologie de laprééclampsie et pour tester de nouvelles approchesthérapeutiques.
Grossesse et HTA
Authors: B. HADDAD  , M. LEFEBVRE  , A. BERMAN  , D. SKALLI  , C. TOUBOUL
Published: April 2022

Les pathologies hypertensives (hypertension artérielle gravidique, prééclampsie, hypertension chronique, prééclampsie surajoutée) chez une femme enceinte sont associées à une augmentation de la morbidité et mortalité maternelle et périnatale. L’analyse des données de la littérature et les avis d’experts permettent de suggérer des critères de surveillance et d’arrêt de la grossesse. Concernant la PE sévère, les indications de l’arrêt de la grossesse peuvent être maternelles (une hypertensionsévère non contrôlée, une éclampsie, un oedème aigu du poumon, un hématome rétroplacentaire, une oligurie persistante, des signes d’imminence d’une crise d’éclampsie (céphalées ou troubles visuels persistants), une douleur épigastrique persistante, un HELLP syndrome, une insuffisance rénale de novo, ou un terme inférieur à 24 semaines d’aménorrhée) ou foetales (la présence d’anomalies du rythme cardiaque foetal, un score de Manning ≤ 4 à 2 reprises, un oligoamnios sévère, une estimation du poids foetal < 5e percentile au-delà de 30 semaines d’aménorrhée, une diastole ombilicale artérielle inversée au-delà de 30 semaines d’aménorrhée. A moins de 34 SA, l’arrêt de la grossesse devra être fait, si possible, après une corticothérapie préventive. En cas de PE peu sévère, l’arrêt de la grossesse doit être envisagé audelà de 36 SA.
Contraception hormonale et dyslipidémies
Authors: ULIETTE GIRARD – ARRIVE  , HORTENSE BAFFET
Published: April 2022

Selon les recommandations de l’HAS de 2015, iln’est pas nécessaire de demander un bilan lipidiqueavant de prescrire une contraception hormonale, s’iln’existe pas d’antécédent personnel ou familial dedyslipidémie ou d’accident vasculaire artériel survenuavant l’âge de 50 ans. Cependant la contraceptionhormonale a un impact plus ou moins importantsur le métabolisme lipidique selon son type et sonmoyen de diffusion. L’effet métabolique négligeabledes contraceptions par micro ou macroprogestatifsfait qu’ils sont à privilégier chez les femmes dyslipidémiques ou à risques métaboliques. Bien que laréalisation d’un bilan lipidique préalable ne soit pasrecommandée, il est primordial de rechercher desfacteurs de risques cardio-vasculaires associés afind’éviter tout risque cumulé. Dans tous les cas, unbilan lipidique doit être pratiqué 3 à 6 mois après ledébut d’une contraception afin de rechercher unedyslipidémie induite par le traitement introduit. Letaux de LDLc ne doit pas être supérieur à 2,20g/l.Si ce taux est dépassé, il est impératif d’arrêter lacontraception en cours.
Implant contraceptif sous-cutané à l’étonogestrel : actualités en 2020
Authors: DR GEOFFROY ROBIN
Published: April 2022

L’implant sous-cutané contraceptif à l’étonogestrel estla méthode de contraception hormonale systémiquela plus efficace. Son profil de tolérance en fait unecontraception de 1ère intention. L’efficacité de cetteméthode n’est pas influencée par l’obésité contrairement à ce qui a été rapporté pendant de nombreusesannées. Les métrorragies intempestives restent leprincipal effet secondaire de cette méthode. Aucuntraitement ne peut aujourd’hui être recommandé pourtraiter cet effet secondaire. Les migrations d’implantsous-cutanée ont récemment inquiété de nombreuxprescripteurs. Ce risque reste extrêmement faibleet peut être prévenu en respectant strictement lecaractère sous-cutané lors de la pose et en modifiantun peu le site d’insertion.
Les contraceptions du futur
Authors: PAULINE MONFORT  , CHARLOTTE NÉLIS
Published: April 2022

La pharmacopée française met à disposition des couplesde nombreuses méthodes de contraception, dontl’efficacité et la tolérance sont bonnes. Il reste toutefoistoujours une grande place pour le développement denouvelles stratégies afin d’améliorer l’acceptabilitéde ces contraceptions en accord notamment avecles évolutions sociétales. L’une des pistes est l’optimisation des méthodes actuellement disponibles etde leur utilisation. La mise au point de nouvellesvoies d’administration des stéroïdes est également unaxe fort. De nouvelles molécules stéroïdiennes sontégalement en développement ou très proches de lacommercialisation. Enfin la contraception hormonaleest toujours une question d’actualité.
Relationship of Organizational Factors to the Implementation Minimum Service Standars in Konawe Regency Health Center
Authors: Aswan Aswan , Saafi La Ode , Harun Aziz
Published: April 2022

Introduction: The initial survey was conducted at 29 Health center in Konawe Regency, it was found that there were several Health center not realizing the overall MSS achievement and there was an accumulation of the average achievement of 12 MSS found in 17 Health center under 80% and all Health center did not implement additional service standards seen from the annual report in Konawe District Health Office. Thus, researchers feel the need to conduct research on the relationship of organizational factors to the implementation of minimum service standards at the Konawe District Health Center.

Method: This type of quantitative research has a population of all officers who have roles and responsibilities for the quality of Public health center services by applying Minimum Service Standards in 29 Public health center totaling 174 and a sample of 122 officers.

Result: Data analysis and obtained the value of X Count or Chi Square 55.03> from 3.84 or X table and the value of Phi 0.695 which means it has a strong relationship.

Conclusion: There is a strong relationship between organizational factors (Resources, Leadership, Compensation, Organizational Structure and Job Design) and Implementation of Minimum Service Standards.
Hematological Changes in Diabetic Rats Receiving Melatonin, Vitamin D and Vitamin E are Not Reliable Indices of Inflammatory Changes
Authors: Alqasim Abdulmonim
Published: April 2022

Background: Finding a suitable model to study the effect of various treatments on diabetes will help to avoid undesirable effect on humans during empirical investigation. This study aims to evaluate the values of biomarkers such as Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR), and Lymphocyte-Monocyte Ratio (LMR) in monitoring diabetes in a rat model subject to treatment with melatonin, vitamin-D and vitamin-E. Methods: Male albino rats (n=8-10 per group), normal and with diabetes were divided as follows into 12 groups: G1 normal fed, received no medications; G2 normal, treated with melatonin; G3 normal, treated with vitamin-E; G4 normal, treated with vitamin-D; G5 diabetic; received no medications; G6 diabetic, treated with insulin; G7 diabetic treated with melatonin; G8 diabetic, treated with melatonin and insulin; G9 diabetic, treated with vitamin-E; G10 diabetic, treated with vitamin-E and insulin; G11 diabetic, treated with vitamin-D and G12 diabetic, treated with vitamin-D and insulin. Two months post-treatment, hematological (NLR, PLR and LMR) and biochemical examination of glucose profile and oxidative stress status, were performed. Results: NLR is significantly decreased on comparing G3 and G4 with G1, and significantly increased on comparing G9 with G1. On comparing G3 with G5 and G6, NLR is significantly decreased, but on comparing G9 with G5 and G6, NLR is significantly increased. However, PLR and LMR showed no statistically significant changes in all rat groups. Conclusion: Hematological changes in diabetic rat model receiving melatonin, vitamin D and E are not reliable indices of inflammatory changes.
Analysis of high voltage shunt capacitor bank over-voltage breakdown detection
Authors:   Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Jalan Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia, Rajabali Pour Mohsen , Azimian Mohammad ,   Engineering Department, Razak Faculty of Technology and Informatics, Universiti Teknologi Malaysia, Jln Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia
Published: April 2022

The traditional over-voltage breakdown detection method ignores the suppression of the inrush current of over-voltage breakdown, resulting in low over-voltage signal detection accuracy and a large detection deviation. As a result, a method is proposed for detecting and analyzing the ageing over-voltage breakdown of high voltage shunt capacitor banks. The breakdown model of aged components of the container group is built to determine the breakdown time of the container's overvoltage. Based on this, the annual load of the capacitor bank's aged component material is evaluated, and data on over-voltage breakdown strength is collected. The Mallet algorithm is used to decompose and convert strength data into electrical signals. The high voltage shunt capacitor's over-voltage breakdown inrush current suppressor is built by combining the second-order under damping circuit and the voltage divider. Based on this, the parameters of HV shunt capacitor overvoltage breakdown are obtained, and the detection of HV shunt capacitor overvoltage breakdown of aged HV shunt capacitor banks is completed. The simulation results show that the proposed detection method's over-voltage breakdown output is in perfect agreement with the monitoring device's actual output and has ideal application performance.
SISTEM INFORMASI APLIKASI REKAM MEDIS BERBASIS WEBSITE MENGGUNAKAN FRAMEWORK CODEIGNITER
Authors: Ahmad Khoirul Murtadho  , Sulaibatul Aslamiyah
Published: April 2022

Klinik merupakan sebuah fasilitas kesehatan publik kecil yang didirikan untuk memberikan pelayanan perawatan kesehatan kepada masyarakat. Klinik hanya mengobati penyakit-penyakit ringan dan pelayanan medis dasar. Permasalahan dari kurang efektifnya pencatatan dan pengolahan data rekam medis yang menggunakan cara manual dengan memanfaatkan dokumen berupa kertas dan aplikasi microsoft excel mengakibatkan proses pencarian data yang begitu lama sehingga mengganggu kinerja. Melihat  permasalahan tersebut, penulis akan membuat sebuah Aplikasi untuk memudahkan dalam proses pengelolaan data pasien dan data rekam medis dengan sebuah Sistem Informasi Aplikasi Rekam Medis Berbasis Website. Dalam pengembangan sistem penulis menggunakan metode perancangan system dengan UML, dan diaplikasikan dengan pembuatan website menggunakan bahasa pemrograman PHPMyAdmin dengan framework CodeIgniter dan database MYSQL. Hasil dari penelitian ini adalah sebuah Sistem Informasi Aplikasi Rekam Medis yang berbasis web. Aplikasi ini diharapkan bisa membantu proses dalam permasalahan yang terjadi dalam melakukan pencatatan rekam medi
Practical reflection and benefits of making a food garden at home during Covid-19 pandemic
Authors: Aditya Rendy Bayu , Zakiah Aisyah
Published: April 2022

The partial lockdown during the Covid-19 pandemic in Indonesia pushed people to work from and spend more time at home. During this unprecedented time, many people pursued new hobbies in gardening, which proved to enhance physical and mental health. With anxieties regarding food insecurity, food gardens became a new urban trend. With a relatively tiny space available, it is possible to make an urban food garden in the front yard of a house using various cultivation techniques to maximize space. However, the implementation of food gardens in urban houses is quite challenging due to limited space. Then, we reflect on the practical process and personal benefits gained from developing a tiny food garden at home. The tiny food garden could produce a variety of vegetables and herbs, such as the spinach family, lettuce, Asian greens, the tomato family, eggplants, the basil family, mint, rosemary, moringas, and butterfly-pea flowers. It may support a household with few amounts of fresh emergency food in the worst scenario during the Covid-19 pandemic. Besides, developing a tiny food garden at home may also provide co-benefits such as enhanced subjective well-being, increased appreciation of food and the environment, motivating others to start gardening at home, and great personal satisfactions of consuming home-grown food. With all these socio-ecological co-benefits, home food garden must be integrated as a strategy to achieve urban sustainability and increase household food resilience.
Stochastic resonance in periodic potential system with memory damping function
Authors: Xu Peng-Fei , Gong Xu-Lu , Li Yi-Wei , Jin Yan-Fei ,   Department of Mathematics, Shanxi Agricultural University, Taigu 030801, China,   School of Software, Shanxi Agricultural University, Taigu 030801, China,   Department of Mechanics, Beijing Institute of Technology, Beijing 100081, China
Published: April 2022

The stochastic dynamical system with memory effects describes a non-Markovian process that can happen in some complex systems or disordered media, such as viscoelastic media and living cell. Its velocity yields the memory effects because of the nonlocality in time, giving rise to a generalized Langevin equation for describing the dynamics of the system. In particular, the friction term in generalized Langevin equation is given by the time-dependent memory kernel. Besides, the research of stochastic resonance in periodic potential models emerges as an important subject because such systems have potential applications in diverse areas of natural sciences. However, the analysis of the influence of memory on stochastic resonance has not been reported so far in periodic potential model. In this paper, the phenomenon of stochastic resonance is investigated in the periodic potential system with friction memory kernel driven by an external periodic signal and internal noise. The generalized Langevin equation is converted into the three-dimensional Markovian Langevin equations. Analytical expression for the spectral amplification, together with the amplitude of the response, is derived in the periodic potential with an arbitrary number of simultaneously stable steady states, which can be applied to the general multi-stable dynamical model. The obtained results indicate that the curve of spectral amplification versus temperature exhibits a pronounced peak. Obviously, this typical phenomenon is a signature of stochastic resonance. The stochastic resonance effect is enhanced with the increase of the memory time or the number of stable steady states. For a certain range of the particle motion, the existence of an optimal number of stable steady states for which the output of the system can be maximized is established. Moreover, the phenomenon of stochastic resonance is studied according to the stochastic energetics. The average input energy per period is calculated over all the trajectories for quantifying stochastic resonance. It is found that the stochastic resonance effect is first weakened and then enhanced with increasing memory time. Specifically, under appropriate temperature conditions, there is an optimal memory time, which can maximize the work done by the external periodic force on the system.
IMPLIKASI APLIKASI E COMMERCE SEBAGAI SITUS BELANJA ONLINE TERHADAP PRILAKU KONSUMTIF
Authors: Hasmawati Fifi
Published: April 2022

Penelitian ini mmelihat implikasi Pengaruh Penggunaan Aplikasi e commer Sebagai Situs Belanja Online terhadap Perilaku Konsumtif,  Penelitian ini menggunakan data kuantitatif, Sampel yang digunakan berdasarkan teknik Proportionate Random Sampling adalah sebanyak 54 pengguna e commerce dalam berbelanja, data yang diperoleh dianalisis menggunakan rumus TSR dan Korelasi Rank Spearman. Adapun teori yang digunakan dalam penelitian ini yaitu Model Use and Gatifications. Hasil dari penelitian yang dilakukan terhadap 54 orang responden ini  menunjukan bahwa 57,4% responden mengimplikasi penggunaan aplikasi e commerce dalam pembelanjaann dan 67,8% responden memiliki pengaruh konsumtif terhadap prilaku mereka.  Maka peneliti menemukan k bahwa terdapat pengaruh yang signifikan antara penggunaan aplikasi e commerce  terhadap perilaku konsumtif.
PERSEPSI MAHASISWA TENTANG URGENSI EMPATI DALAM BERKOMUNIKASI DI ERA 5.0
Authors: Jannati Zhila , Hamandia Muhammad Randicha
Published: April 2022

Sejatinya, empati yang tinggi dapat membawa individu untuk meraih kebahagiaan hidup melalui pencapaian hubungan yang baik, hangat dan nyaman dengan orang lain. Tujuan dari penelitian ini ialah untuk mengetahui bagaimana persepsi mahasiswa tentang urgensi empati dalam berkomunikasi di era society 5.0. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif. Adapun teknik pengumpulan data yang digunaka dalam penelitian ini ialah teknik dokumentasi, teknik observasi, serta teknik wawancara. Subjek dalam penelitian ini adalah mahasiswa Bimbingan dan Penyuluhan Islam Fakultas Dakwah dan Komunikasi UIN Raden Fatah Palembang dengan jumlah yaitu sepuluh orang mahasiswa. Kemudian, teknik analisis data yang dipakai pada penelitian ini yaitu teknik analisis deskriptif kualitatif. Hasil penelitian menunjukkan bahwa persepsi mahasiswa tentang urgensi empati dalam berkomunikasi di era 5.0. yaitu positif di mana empati memiliki peran yang sangat penting agar dapat terciptanya komunikasi baik, benar, bermanfaat sehingga yang dapat mencapai tujuan yang telah ditentukan baik komunikasi yang dilakukan secara langsung maupun secara tidak langsung melalui media komunikasi.
Kedudukan Dan Peran Dukun Bayi Dalam Kebudayaan Masyarakat Jawa Di Desa Muara Intan, Kecamatan Tapung Hulu, Kabupaten Ampar, Provinsi Riau
Authors: Fatmawati Retno , Rochmiatun Endang , Amilda Amilda
Published: April 2022

Penelitian ini berusaha mendeskripsikan keberadaan dukun bayi dengan menggunakan teori fungsionalnya Malinowski. Secara historis, dukun bayi mempunyai peran penting dalam perawatan pra-pasca persalinan, tetapi sekarang keberadaan dukun bayi mulai ditinggalkan. Namun, terdapat beberapa kelompok masyarakat yang masih mempertahankan keberadaan dukun bayi, salah satunya adalah masyarakat Desa Muara Intan. Kajian ini difokuskan untuk menjawab permasalahan antara lain: (1) Kondisi umum masyarakat di Desa Muara Intan; (2) Peran dukun bayi yang ada di Desa Muara Intan; dan (3) Kedudukan dukun bayi yang ada di Desa Muara Intan. Metode yang digunakan adalah etnografi dengan menggunakan teknik observasi partisipan, wawancara, dokumentasi, serta mengumpulkan materi audio-visual berupa gambar, foto, ataupun rekaman. Analisis data akan berlangsung bersamaan dengan bagian-bagian lain dari pengembangan penelitian ini, yaitu pengumpulan data dan penulisan temuan.

Adapun yang menjadi fokus penelitian ini adalah dukun bayi dan masyarakat yang menggunakan jasa dukun bayi tersebut. Hasil penelitian ini menunjukkan bahwa keberadaan dukun bayi masih tetap terjaga dikarenakan kebutuhan biologis masyarakat yang belum terpenuhi hanya dengan bantuan tenaga medis. Terutama dalam memenuhi kebutuhan reproduksi, yaitu pada masa kehamilan, melahirkan, setelah melahirkan, menyusui, dan perawatan bayi. Mempertahankan budaya bukanlah alasan utama, tetapi karena tetap terjaganya keberadaan dukun bayi inilah yang menjadikan suatu tradisi di masyarakat. Berkaitan dengan hal tersebut, maka diperlukanlah regenerasi terhadap dukun bayi, agar keberadaan dukun bayi tetap terjaga ditengah masyarakat.