bluuebunny/crossref_metadata_2025 huggingface dataset:
Pitfalls at Chemistry of Adenoviral Vector Vaccine against COVID-19 and how to Circumvent It.
Authors: Ahmed Amr Kamel Khalil , Alkattan Abdullah
Published: July 2021

ChAdOx1 nCoV-19 vaccine is an adenovirus vector vaccine that designed to provoke immunity against SARS-CoV-2.This vaccine contains several inactive ingredients, including sodium chloride, magnesium chloride hexahydrate, ethanol, sucrose, and Ethylenediaminetetraacetic acid (EDTA).EDTA is a very potent zinc chelator which is used commonly in protein interaction studies. Exposure to EDTA even in lower concentrations may cause extreme stripping of zinc from many proteins, in-cluding zinc-binding proteins that described as a component of the largest and most complex gene superfamily in metazoans and the most common class of transcription factors.the EDTA-induced thrombocytopenia is a risk phenomenon caused by EDTA-dependent anti-platelet auto-antibodies that identify antigens modified by EDTA.Another issue is the adenovirus in the vaccine. It can induce thrombocytopenia, a potentially serious complication of gene therapy protocols using this type of vector.PEGylation already induced significantly lower serum il-6 levels by 70% (14)We noted that the study by Katie et al studied immune response by a single dose of ChAdOx1 nCov-19 not included test of Il-6 (15)We conclude from previous studies that the PEGylating of adenoviral vectors can be promise tech-nology as safety profile as significantly reduced IL-6 and liver toxicity and how avoiding the pitfalls of chemistry and virology so the PEGylation since first time at 1999 introduced by O’Riordan,C.R et al (16) need more advancements
Verifying Primers For Point Mutation Using Primers To Amplify DNA Region Containing Mutation Site
Authors: Shukla Halak
Published: July 2021

Analysing DNA sequences for determining mutation point in PCR needs paid, Hi-tech software tools but we can confidently order the right piece of primer by this simple and easy method before we do PCR in lab. For instance, we here take BRAF V600E mutation. This method is to verify that the primers you’ve got or designed would successfully amplify the same region of DNA you want and not somewhere else.
A Study of Emotional Intelligence of Electrical Engineering students in Dire Dawa University Ethiopia
Authors: Jibril Mustefa
Published: July 2021

The present study was carried out to study the emotional intelligence of Electrical Engineering students in Dire Dawa University Ethiopia. The sample for the study was 90 (30 Industrial control engineering streams, 30 Power system engineering streams, and 30 Communication engineering streams) randomly selected from Dire Dawa university, school of electrical and computer engineering. A sample scale was employed for the data collection and a t-test was employed for the analysis of data. The outcome of the study shows that Industrial control engineering and Power system engineering students do not differ significantly on various dimensions of Emotional intelligence and Industrial control engineering and Communication engineering students do not differ significantly on various dimensions of Emotional intelligence and Power system engineering and Communication engineering students differ significantly on various dimensions of Emotional intelligence.
Serum biochemical reference ranges for pregnant sheep
Authors: Varanis Laura Ferrari Monteiro , Oliveira Karla Alves , Araújo Carolina Moreira , Guimarães da Cruz Wendell Fernando , Macedo Júnior Gilberto de Lima
Published: July 2021

Late pregnancy is accompanied by dramatic changes in the metabolism of sheep, in which the nutrient requirements increase and the metabolic capacity of ewes is under severe stress due to the rapid foetal growth and development of the mammary gland. The blood metabolic profile can be used to monitor these alterations, which can lead to metabolic disorders such as pregnancy toxaemia. However, data available on serum parameters in sheep do not consider physiological state. Therefore, the present study aimed to determine the biochemical reference ranges for pregnant ewes, including serum energy, protein and enzyme-related metabolites. Data from a variety of metabolites were obtained from experiments performed in several institutions and commercial farms using Santa Inês, Dorper, Lacaune, Morada Nova, Bergamacia and Suffolk ewes reared under different conditions (grazing, feedlot, semi-feedlot, collective and/or individual pens, and metabolic cages) from 2006 to 2017. All animals were healthy and without feed restriction. Data from ewes with any clinical manifestations were removed. The metabolic energy profile included data of glucose, cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein and very-low-density lipoprotein levels; the metabolic protein profile included the metabolites total protein, uric acid, urea, albumin, and creatinine; and the metabolic enzymatic profile included the enzymes aspartate aminotransferase, gamma-glutamyl transferase and alkaline phosphatase. The reference ranges were estimated using the software RefVal 4.11. Dixon’s test was used to identify and remove outliers. The confidence intervals and percentiles were estimated using the nonparametric method of bootstrap when data were not normally distributed. A 95% confidence level was used. The serum biochemical reference ranges for pregnant sheep determined in our study were strongly divergent from those established by one of the most cited books on the topic, especially considering the high serum urea and cholesterol concentrations and low levels of blood glucose observed. Therefore, it is essential to consider physiological status when evaluating the blood metabolic profile of pregnant ewes in order to maintain an adequate nutritional management and to prevent health disorders that may lead to productive and reproductive losses.
Effect of reciprocating instrumentation on chlorhexidine substantivity on human dentin: chemical analysis followed by confocal laser microscopy
Authors: Souza Matheus Albino , Bonatto Fernanda Duda , Fleck da Silva Afonso Cristiano , Gabrielli Ezequiel Santin , Motter Felipe Trentin , Piuco Larissa , Duarte Karen Barea de Paula , Bertol Charise Dallazem , Rossato-Grando Luciana Grazziotin , Lago Carlo Theodoro Raimundy , Cecchin Doglas , Bervian Juliane , De Carli João Paulo , Montagner Francisco
Published: July 2021

The present research analyzed the reciprocating instrumentation associated to chlorhexidine (CHX) substantivity as its correlation with E. faecalis viability in ex vivo root canals. Eighty extracted single-rooted human teeth were used, being 40 to high-performance liquid chromatography (HPLC) and 40 to confocal laser scanning microscopy (CLSM). In both, teeth were decoronated and the cervical third was prepared. In the CLSM analysis, the root canals were inoculated with E. faecalis for 14 days. Samples were divided into 4 groups (n=10) according to instrumentation technique: no instrumentation and irrigation with distilled water (control); manual instrumentation (K-File); rotary instrumentation (ProTaper Next); and reciprocating instrumentation (Reciproc R25). Two percent chlorhexidine was applied as irrigating substance in experimental groups. Longitudinal grooves resulted in 2 halves root and 20 proof bodies in each group. Samples were divided by chance in two groups (n=10) and the outcomes were evaluated after two days and one week. The retained chlorhexidine and live cells after instrumentation techniques in each evaluation time was measured by HPLC and CLSM, respectively. Specific analysis was applied for experimental tests (p≤0.05). Both rotary as well as reciprocating techniques significantly reduced the amount of chlorhexidine on dentin in all observation periods (p<0.05). After evaluation times, all experimental groups presented lower live cells compared to control, but without statistically difference. Intragroup comparisons in times of evaluation showed no differences in instrumentation techniques, in chlorhexidine retention and number of live cells (p>0.05). Reciprocating instrumentation does not interfere on chlorhexidine substantivity.
Resenha / Extensão Universitária: trajetórias e desafios
Authors: Balduíno Santos Alfredo
Published: July 2021

O livro Extensão Universitária: trajetórias e desafios da amiga Professora Sandra de Deus é para todas/os as/os extensionistas uma grande contribuição. Sua luta e paixão pela Extensão Universitária ficam evidentes. O texto reflete a organização dos manuscritos de suas palestras ou de outras publicações e nos permitem mergulhar em pensamentos e propostas que colocam à extensão universitária desafios em relação a sua importância na função social das instituições de ensino superior no Brasil. A obra leva a reflexões acerca do tema, que sem dúvidas é a referência de uma vida de dedicação e percepção de uma Universidade integradora e dialógica, num exercício de troca contínua. Onde cada tópico abordado nos possibilita rememorar a luta pessoal e coletiva, de pessoas ligadas e interligadas com as emoções de pensar e caminhar com perseverança, essa trilha com todos os seus obstáculos.
RESILIÊNCIA DE ALUNOS UNIVERSITÁRIOS DURANTE A PANDEMIA – COVID 19
Authors: Perpétuo dos Santos Jadir , Paubel Junger Alex , de Santana Brito Alan , de Alcântara Thimóteo Antônio Carlos , Fontana Cristiane , de Souza José Ferreira , Amaral Luiz Henrique
Published: July 2021

O artigo tem por objetivo entender melhor o pensamento dos alunos em meio a pandemia no Brasil, considerando a resiliência dos educandos universitários nesse contexto, a metodologia para atingir tal objetivo se apresenta em três fases: a fase 01 acontece em pesquisa de bases de dados primários e secundários, a fase 02, se estabelece por meio de um questionário usado para sistematizar a investigação da pesquisa na busca do conhecimento epistemológico e a fase 3, se constitui através de uma pesquisa quali-quantitativa, onde os dados são aferidos testando a teoria da resiliência. Assim, foram destacados em caráter positivo, os seguintes aspectos no que tange a resiliência: autocontrole, rede de apoio, análise de ambiente, tenacidade e alta eficácia, podendo ser utilizados para otimização do desempenho educacional em momentos de crise, inclusive, sendo considerado como atenuante para esse contexto
FERRAMENTA COMPUTACIONAL $AVEPI COMO SUPORTE PARA O PROCESSO DE ENSINO E APRENDIZAGEM DE ENGENHARIA ECONÔMICA
Authors: de Lima José Donizetti , Amorim Colombo Janecler Aparecida , Dranka Géremi Gilson , Adamczuk Oliveira Gilson
Published: July 2021

O objetivo deste texto é discorrer sobre o uso da ferramenta computacional de acesso livre $AVEPI® em contextos reais, de ensino de graduação e de pós-graduação na UTFPR. O desenvolvimento do software foi iniciado em 2016 com o intuito de auxiliar o processo de ensino e aprendizagem de Engenharia Econômica (EE). Sua principal finalidade é aprimorar a abordagem pedagógica associada às novas tendências da educação, permitindo que alunos e educadores simulem problemas de EE de acordo com o nível de competências individuais e ampliem os domínios de conhecimento. O $AVEPI® apresentou-se como uma alternativa eficiente para auxiliar na inovação da prática docente, contribuindo para: (i) a realização de aulas teóricas e práticas; (ii) a melhoria da autonomia do discente; (iii) a resolução de problemas reais, articulando conhecimentos teóricos e práticos; e (iv) o desenvolvimento de competências exigidas pelo mercado. Além disso, constatou-se que o $AVEPI® pode diminuir as barreiras para empresas e indivíduos realizarem a avaliação econômica de ativos reais, pois fornece uma maneira simples de alterar os dados de entrada durante o desenvolvimento de um projeto. Também mostrou potencial para facilitar a pesquisa interdisciplinar em EE, atuando como uma ferramenta de uso prático tanto para a academia quanto para a indústria.
ATATÜRK’ÜN YÖNETİM ORGANİZASYON ALANINA BİR KATKISI: SEVGİ- SAYGI, GÜVEN – OTORİTEYE İTAAT, İŞ DİSİPLİNİ VE HUZURUN KARİYER BAŞARISINA ETKİSİ
Authors: BİLGİNOĞLU Elif , YOZGAT Uğur , ERDEM ARTAN İnci
Published: July 2021

Türkiye Cumhuriyeti’nin kurucusu Mustafa Kemal Atatürk’ün “Nerede karşılıklı sevgi ve saygı varsa, orada itimat ve itaat vardır. İtimat ve itaatin olduğu yerde disiplin vardır. Disiplinin olduğu yerde huzur, huzurun olduğu yerde başarı vardır.” özdeyişinin günümüz örgütlerinde geçerliliği irdeleyen bu çalışma, bu özdeyişten hareketle, örgütlerde kariyer başarısının öncelleri ve bu değişkenlerin birbirleriyle ilişkilerini ölçmeyi amaçlamaktadır. Anketi cevaplayan 473 çalışandan elde edilen verilerin analizi sonucunda sevgi ve saygının güven ve itaat, güven ve itaatin iş disiplini, iş disiplinin huzur, huzurun da kariyer başarısı üzerinde olumlu etkisi olduğu belirlenmiştir.
Pre-analytical considerations in biomarker research: focus on cardiovascular disease
Authors: Revuelta-López Elena , Barallat Jaume , Cserkóová Adriana , Gálvez-Montón Carolina , Jaffe Allan S. , Januzzi James L. , Bayes-Genis Antoni
Published: July 2021

Clinical biomarker research is growing at a fast pace, particularly in the cardiovascular field, due to the demanding requirement to provide personalized precision medicine. The lack of a distinct molecular signature for each cardiovascular derangement results in a one-size-fits-all diagnostic and therapeutic approach, which may partially explain suboptimal outcomes in heterogeneous cardiovascular diseases (e.g., heart failure with preserved ejection fraction). A multidimensional approach using different biomarkers is quickly evolving, but it is necessary to consider pre-analytical variables, those to which a biological sample is subject before being analyzed, namely sample collection, handling, processing, and storage. Pre-analytical errors can induce systematic bias and imprecision, which may compromise research results, and are easy to avoid with an adequate study design. Academic clinicians and investigators must be aware of the basic considerations for biospecimen management and essential pre-analytical recommendations as lynchpin for biological material to provide efficient and valid data.
Discrepancy between emergency department admission diagnosis and hospital discharge diagnosis and its impact on length of stay, up-triage to the intensive care unit, and mortality
Authors: Bastakoti Manish , Muhailan Mohamad , Nassar Ahmad , Sallam Tariq , Desale Sameer , Fouda Ragai , Ammar Hussam , Cole Carmella
Published: July 2021

Objectives

Published discrepancy rates between emergency department (ED) and hospital discharge (HD) diagnoses vary widely (from 6.5 to 75.6%). The goal of this study was to determine the extent of diagnostic discrepancy and its impact on length of hospital stay (LOS), up-triage to the intensive care unit (ICU) and in-hospital mortality.

Methods

A retrospective chart review of adult patients admitted from the ED to a hospitalist service at a tertiary hospital was performed. The ED and HD diagnoses were compared and classified as concordant, discordant, or symptom diagnoses according to predefined criteria. Logistic regression analysis was conducted to examine the associations of diagnostic discordance with in-hospital mortality and up-triage to the ICU. A linear regression model was used for the length of stay.

Results

Of the 636 patients whose records were reviewed, 418 (217 [51.9%] women, with a mean age of 64.1 years) were included. Overall, 318 patients (76%) had concordant diagnoses, while 91 (21.77%) had discordant diagnoses. Only 9 patients (2.15%) had symptom diagnoses. A discordant diagnosis was associated with increased mortality (OR: 3.64; 95% CI: 1.026–12.91; p=0.045) and up-triage to the ICU (OR: 5.51; 95% CI: 2.43–12.5; p<0.001). The median LOS was significantly greater for patients with discordant diagnoses (7 days) than for those with concordant diagnoses (4.7 days) (p=0.004). Symptom diagnosis did not affect the mortality or ICU up-triage.

Conclusions

One in five hospitalized patients had discordant HD and admission diagnoses. This diagnostic discrepancy was associated with significant impacts on patient morbidity and mortality.
Illustrationen zu den Kinder- und Hausmärchen der Brüder Grimm in koreanischen Ausgaben
Authors: Hyun Sook Shin
Published: July 2021

Dieser Beitrag rekapituliert die Illustrationsgeschichte zu den Kinder- und Hausmärchen in Korea. Nach einem Überblick über drei Phasen (1910 bis 1923, 1945 bis 1989, 1990 bis heute) werden exemplarisch einzelne Illustrationen aus drei Publikationen untersucht, und zwar: 1. aus Dongmyeong
(Ex Oriente Lux), die eine der populärsten Zeitschriften in den frühen 1920er Jahren war; 2. Illustrationen von Hong Seong-Chan aus der 1964 erschienenen Ausgabe Grimms Märchenanthologie, die als Meilenstein der Übersetzungsgeschichte gilt und mit ihren Illustrationen Maßstäbe gesetzt hat. Schließlich werden 3. Illustrationen von Park Eunji vorgestellt, die in der vorbildlichen Ausgabe Die Volkserzählungen der Brüder Grimm (2012) erschienen sind. Ein besonderes Augenmerk legt die Darstellung darauf, Anpassungen an die koreanische Kultur und Lebensweise herauszuarbeiten. Jedoch weist der Forschungsstand immer noch Lücken auf, die auch in diesem Beitrag nicht geschlossen werden können und die vor allem die Zeit von 1924 bis 1945 betreffen.
Image-based 3D reconstruction precision using a camera mounted on a robot arm
Authors: Jezia Yousfi , Samir Lahouar , Abdelmajid Ben Amara
Published: July 2021

In this paper, we study 3D object reconstruction based on a set of 2D images. In order to get the best camera path that increases accuracy we focus on this strategy to be used. Euclidean 3D image-based reconstruction is developed in three steps, which are primitive extraction, correspondence of these primitives and then triangulation. The extraction and triangulation are purely geometrical, whereas the matching step can have precision issues especially in the case of noisy images. An experimental study is carried out where a camera is attached to a robot arm and moved precisely relative to a scene containing a checkerboard calibration pattern. The reconstruction results are compared with values of motion given to the robot. A geometric and analytical study of the impact of the motion of the camera with respect to the scene on the error of a 3D image-based reconstructed point was also carried out. It has been demonstrated that the impact of a correspondence error on the reconstruction accuracy point varies drastically depending on the image capture strategy.
Non-invasive prenatal testing (NIPT): does the practice discriminate against persons with disabilities?
Authors: Dufner Annette
Published: July 2021

The most well-known goal of non-invasive prenatal testing (NIPT) is still to determine whether or not a fetus has trisomy 21. Since women often terminate the pregnancy upon a positive result, there is concern that the use of NIPT contributes to discrimination against persons with disabilities. If this concern is justified, it could have an impact on the wider social acceptability of existing testing practices and their potential further expansion. This paper demonstrates four different versions of the discrimination worry, indicates how international policy papers have reacted to them, and identifies the ethically most relevant feature of the concern.
Inviscid, zero Froude number limit of the viscous shallow water system
Authors: Yang Jianwei , Liu Mengyu , Hao Huiyun
Published: July 2021

In this paper, we study the inviscid and zero Froude number limits of the viscous shallow water system. We prove that the limit system is represented by the incompressible Euler equations on the whole space. Furthermore, the rate of convergence is also obtained.
“It is natural, really deaf signing” – script development for fictional programmes involving sign languages
Authors: Kusters Annelies , Fenlon Jordan
Published: July 2021

Historically, fictional productions which use sign language have often begun with scripts that use the written version of a spoken language. This can be a challenge for deaf actors as they must translate the written word to a performed sign language text. Here, we explore script development inSmall World, a television comedy which attempted to avoid this challenge by using improvisation to create their script. The creators framed this process as a response to what they saw as “inauthentic” sign language use on television, foregrounding the need to present “natural signing” on the screen. According to them, “natural signing” is not influenced by an English script but is varied language use that reflect a character’s background, their settings, and the characters that they interact with. We describe how this authentic language use is derived primarily from improvisation and is in competition with other demands, which are textual (e.g., the need to ensure comedic value), studio-based (e.g., operating within the practical confines of the studio), or related to audience design (e.g., the need to ensure comprehensibility). We discuss how the creative team negotiated the tension between the quest for authentic language use and characteristics of the genre, medium, and audience.
Crystal structure of (1,10-phenanthroline-κ2
N,N′)-bis(3-thiophenecarboxylato-κ2
O,O′)copper(II), C22H14N2O4S2Cu
Authors: Zhang Zhongyu , Men Xiaoxia , Han Bing , Sun Chunyan
Published: July 2021

C22H14N2O4S2Cu, orthorhombic, Pbcn (no. 60), a = 20.171(7) Å, b = 9.684(3) Å, c = 10.372(4) Å, V = 2025.9(12) Å3, Z = 4, R

gt
(F) = 0.0334, wR

ref
(F
2) = 0.0908, T = 273.15 K.
Analysis of Record Scores in the Clean and Its Variations in the Long-Term Training of Young Weightlifters
Authors: Szyszka Paulina , Czaplicki Adam
Published: July 2021

Szyszka, P and Czaplicki, A. Analysis of record scores in the clean and its variations in the long-term training of young weightlifters. J Strength Cond Res 35(9): 2383–2388, 2021—The main objectives of this study were to determine the time trajectories of record scores in the clean lift (C) and its derivatives achieved by young weightlifters in a 2-year training cycle and to estimate the quantitative relationships between these scores. The study involved 17 weightlifters who were tested 7 times at 3-month intervals. The computations were based on an individual growth curve approach. The study found statistically significant increases (p < 0.05) in record scores between consecutive measurements until the last measurement for the hang clean (HC), the second to last measurement for the C, and the fourth measurement for the power clean (PC) and the hang power clean (HPC). The overall mean ratios of the record scores in the C to those in the HC, PC, and HPC were approximately constant and amounted to 0.96, 0.89, and 0.80, respectively. Statistically significant differences (p < 0.05) between individual time trajectories of record scores in the C and its derivatives were also identified in the 2 consecutive annual training macrocycles. The results suggest that the long-term analysis of record scores in the C and its derivatives can be useful in assessing athletes' sport level, in predicting their performance, and in proper exercise selection in the training of young weightlifters.
Die Covid-19-Pandemie und Wirtschaftskrisen: die Mehrfachbelastungen von Frauen in Privathaushalten
Authors: Wöhl Stefanie , Lichtenberger Hanna
Published: July 2021

In diesem Beitrag setzen wir die unbezahlte soziale Reproduktionsarbeit von Frauen in Privathaushalten ins Ver- hältnis zu bezahlter (Pflege-)Arbeit im Kontext der letzten Finanz- und Wirtschaftskrise 2008 in Spanien und der jetzigen Covid-19-Pandemie in Österreich. Dadurch werden zwei Aspekte deutlich: Erstens, welche gravierenden Konsequenzen die Einsparungen im öffentlichen Sektor seit 2010 und neue EU-Vorgaben seitdem für die Sozial- und Gesundheitssysteme haben (Spanien); zweitens, dass besonders in Krisenzeiten einer globalen Pandemie die Mehr- fachbelastungen von Frauen in Privathaushalten in der sozialen Reproduktion deutlich zutage treten (Österreich).
Flexible Mass Spring Method for Modelling Soft Tissue Deformation
Authors: Omar Mohd Nadzeri , Zhong Yongmin
Published: July 2021

It is well accepted that soft tissue deformation is a combination of linear and nonlinear response. During small displacements, soft tissues deform linearly while during large displacements, soft tissues show nonlinear deformation. This paper presents a new approach for modelling of soft tissue deformation, from the standpoint of Mass Spring Method (MSM). The proposed MSM model is developed using conical spring methodology which allow the MSM model to have different stiffnesses at different displacements during deformation. The stiffness variation creates flexibility in the model to simulate any linear and nonlinear deformations. Experimental results demonstrate that the deformations by the proposed method are in good agreement with those real and phantom soft tissue deformations. Isotropic and anisotropic deformations can be accommodated by the proposed methodology via conical spring geometry and configuration of the springs. The proposed model also able to simulate typical viscoelastic behaviour of soft tissue.
The impact of anti-reflective coating and optical bandpass interference filter on solar cell electrical-thermal performance
Authors: Tay Justin C-K , Wong Basil T. , Chong Kok Hing
Published: July 2021

Solar cells utilize only the visible region of the electromagnetic spectrum to generate electricity. A great reduction in the temperature of a solar cell resulting from filtering infrared and ultraviolet wavelengths will eventually lead to an increase in efficiency. Here, a detailed analysis of the use of an optical bandpass interference filter with antireflective coating as a potential solution to this problem has been carried out. The optical bandpass filter aims to filter out unwanted wavelengths while the antireflective coating functions to reduce the amount of light reflected from the solar panel surface. A simulation program using SolidWorks (Flow Simulation Study) has been performed to demonstrate the effect of utilizing optical bandpass interference filter with antireflective coating on solar panel and the temperature of each cell layer. The thermal analysis results obtained from SolidWorks were then exported to MATLAB/Simulink to investigate the electrical output parameters. Results showed that optical bandpass interference filter combined with antireflective coating could reduce the temperature of the solar cell by 11.83 Kelvin which led to 14.32% increase in the maximum output power within an hour of exposure to peak solar radiation located in Kuala Lumpur, Malaysia.
The Existence Of Al-Madaris Terbangan Music In Pladen Village, Jekulo District, Kudus Regency
Authors: Wahyu Muhammad Panji , Sinaga Syahrul Syah
Published: July 2021

The existence of Al-Madais' terbangan music group in Pladen Village cannot be separated from the motivation of its members to preserve the terbangan music as a means of da'wah and worship. Despite the limited time, facilities, and infrastructure as well as knowledge and skills, the group still strives to preserve Islamic culture amid the fast growth of the modern era. Therefore, the purpose of this study is to describe the existence of Al-Madais' terbangan music arts. This study uses a qualitative descriptive method, with data collection techniques through observation, interviews, and documentation. Meanwhile, the data analysis technique was carried out by reducing, presenting, and verifying data. The results of the study indicate that the existence of the Al-Madais terbangan music group, in terms of the adopted strategy, one of which is good management. Then in terms of consistency, it is carried out with the existence of an organizational structure, regeneration process, and mundane rehearsal. The innovation is carried out by imagination and creativity without leaving its cohesiveness and characteristics. The acknowledgment of the Al-Madais existence is proved by performing at various events and support from the government.
The Interest Of Classic Piano Student In Semarang Music Course
Authors: Widjajantie Kusrina , Nugroho Agustinus Dwi Eka Arum
Published: July 2021

The community is very enthusiastic about welcoming music education institutions. There are many people's desire to learn music, especially piano, but not all students have the same interest in learning music. In this case the researchers limited the classical piano participants, with ages 4-6 years. Based on observations, the classical piano learning process has a very detailed learning stage, so that students experience boredom in learning. Seeing this fact, the researcher wanted to know the students' interest in learning classical piano in the Music course in Semarang. The benefit of this research is to know the students' interest in learning classical piano. So that these results can be used for the development of methods, materials, strategies, and media in classical piano learning. The development of this learning component has a beneficial impact on the owners of educational institutions, teachers and students.

The result of the discussion is that interest has a great influence on students in learning, because if the material and learning methods are not in accordance with their interests, students will not learn as well as possible, because there is no attraction for them. For students aged 4-6 years, students cannot achieve learning goals just because of interest, but other psychological factors such as intelligence, attention, talent, maturity, readiness, especially motivation that can help return the initial interest, namely learning the piano. Motivation from the closest people, usually parents play an important role in the growth of interest.
Association between heart rate-corrected QT interval and severe peripheral arterial disease in patients with type 2 diabetes and foot ulcers
Authors: Hong Jing , Liu Wen-Yue , Hu Xiang , Jiang Fei-Fei , Xu Ze-Ru , Li Fang , Shen Fei-Xia , Zhu Hong
Published: July 2021

Background

A prolonged heart rate-corrected QT interval (QTc) has been associated with peripheral artery disease (PAD) in the general population. However, no study to date has identified a link between prolonged QTc and the severity of PAD in patients with diabetes mellitus and foot ulcers (DFUs). This study aimed to investigate this relationship.

Methods

This multicenter study enrolled 281 patients with DFUs. The severity of PAD was classified into no severe PAD group (without stenosis or occlusion) and severe PAD group (with stenosis or occlusion) based on duplex ultrasonography. The association of prolonged QTc with severe PAD was evaluated in a multivariable mixed-effect logistic regression model, with the hospital as a random effect. Directed acyclic graphs were used to drive the selection of variables to fit the regression model.

Results

Patients with severe PAD had longer QTc than those without. Based on the multivariable mixed-effect logistic regression model, a prolonged QTc was positively associated with severe PAD (odds ratio (OR) = 2.61; 95% CI: 1.07–6.35) and severe DFUs (Wagner grade score ≥ 3) (OR = 2.87; 95% CI: 1.42–5.81).

Conclusions

A prolonged QTc was associated with severe PAD in patients with DFUs. Further research is required to ascertain whether the association is causal.
Política y corrupción en la corte isabelina. El ascenso «Clan de Tarancón»
Authors: Martínez García Cristina Bienvenida
Published: July 2021

A comienzos del siglo XIX se consumó el cambio de las estructuras del Estado y de la sociedad. Aunque el nuevo Estado gobernó con igualdad, a través de sus instituciones, a toda la sociedad, en la práctica no desaparecieron las formas y métodos del gobierno cortesano, basados en las relaciones no institucionales (familiares, patronazgo, clientelismo, etc.). En el nuevo Estado, este comportamiento, es lo que constituye la corrupción. La familia de Fernando Muñoz utilizó la relación que tenía con la reina para conseguir títulos y negocios, que le llevaron a introducirse en la alta burguesía de la sociedad española del siglo XIX y en los partidos políticos.
Representación cortesana en unos libros de caballerías renacentistas.: La conversación y la fiesta en el Amadís de Gaula y en el Esferamundi de Grecia
Authors: Bognolo Anna
Published: July 2021

El articulo presenta dos casos ejemplares, a partir de la definición del perfecto cortesano elaborada por Castiglione en su diálogo Il Cortegiano, y de los comentarios de Amedeo Quondam sobre la importancia, en esta “forma del vivere”, de la conversación y de las habilidades cortesanas. La “gracia” de la vida de corte se muestra en los libros de caballerías; el análisis de dos episodios del Amadís y del Esferamundi de Grecia a distancia de 60 años, entre España e Italia, permite notar el perdurar de esta forma de vida en sus varios matices, donde las variaciones más maduras acentúan los detalles maravillosos de palacios y jardines y destacan el protagonismo femenino.
How to Become an Author: The Poet Isa Asp and Her Childhood Fascination with Writing for Magazines
Authors: Kotilainen Sofia
Published: July 2021

In this article the author explores the early development of the identity as a writer of a Finnish-speaking poet Lovisa (or Isa) Asp (1853–1872). She wrote her lyrics in the Finnish language in the 1870s, and she is regarded as the first 19th-century female Finnish poet (whose works were published in Finnish). She began writing poetry (initially in Swedish) as a teenager and started her literary career as a contributor to children’s magazines. Asp began her studies at the Teacher Training College in Jyväskylä in autumn 1871 with the aim of working as an elementary school teacher, but she also dreamt of becoming an established writer someday. Unfortunately, her early death meant that most of her poetry remained unpublished until the 21st century.

The author investigates what kind of literature Asp read and why she was able to read extensively as a child in the remote Finnish-speaking countryside at a time when Finnish-language literature for children was scarce and still only nascent and being developed for nationalistic reasons; in those decades, most of the books and publications were still written in Swedish. The author analyses in particular the gendered experiences of reading (and writing) in the life of a young girl and woman from the countryside, because in those days most of the authors were men living in towns. A special focus of the article is on the texts that she wrote and edited for children’s magazines. The author studies her autobiographical sources using a biographical method and considers what kind of literature and libraries inspired her career as an early female poet.

National poet Johan Ludvig Runeberg and poet and historian Zacharias Topelius, the major Fennoman authors, were the literary models for the young Isa Asp. Their works inspired her to write and to aspire for a career as a poet and author, an occupation that was then still rare for a woman. Writing for children’s magazines was a crucial stage in her career, and her identity as a writer was strengthened by the opportunity to have her poems and short tales published. Also, writing for these handwritten as well as published magazines made her dreams visible and encouraged her to pursue them with effort. All this shows that her development as a writer was a deliberate, goal-oriented process. The publication of her poems and obtaining the community’s approval of them were important for the young poet. The encouragement to pursue a career in writing that Isa with her literary gifts received as a child from her immediate surroundings helped her to achieve her dreams, which in the end turned out not to be impossible to realise.
Reading Girls’ Literature: Popular Finnish Heroine Tiina
Authors: Kokkonen Sara
Published: July 2021

The Tiina book series for girls circulated in Finland for a considerable period of thirty years (1956–1986). This girls’ series was quite popular among young girls during the whole period, and the protagonist Tiina has appealed to young Finnish readers for decades. Different generations have read the girls’ books about the brave and tomboy heroine. Girls’ series books are part of the girls’ literature genre, which was developed originally in the mid-nineteenth century. This article explores the reading and reception of Tiina books in the context of the Finnish and international girls’ literature and reading research. Female readers of various ages participated in a reading survey and submitted written accounts of their experiences reading the Tiina books. In particular, this article seeks to examine the engagement of readers with the books and the girl protagonist.
Roles of Local Information Professionals of the Thai Provincial University Libraries
Authors: Nonthacumjane Pussadee
Published: July 2021

This paper aims to investigate the roles of information professionals in local information departments. These roles were identified by interviewing the members of the Local Information Working Group of the Provincial University Library Network (PULINET) in Thailand. This study applied qualitative research methods, including the 23 interviews of the Local Information Working Group members and a qualitative observation. The need for investigation of the roles as perceived by local information professionals was prompted by the placement of local information departments in the provincial university libraries, which is different from the Western countries where similar work is carried out in public libraries. The activity theory was applied to understand the roles of these professionals as emerging within their community through the division of labor, norms as expressed in responsibilities, and actions as expressed in functions of local information professionals. The study has revealed eight professional roles including manager, curator, service provider, promoter, researcher, collaborator, learner, and educator that overlap with the roles identified in the library research of other countries. The study included a specific group of respondents – the members of a working group of the Thai provincial university library network. This group consists of the representatives of all Thai provincial university libraries and is producing the recommendations and standards for local information work, works with competence development and develops common local information resources. Thus, the results of interviews with its members are both limited to this group, but also can be generalized to a wider professional community of provincial university librarians.
Statistical Indicators of Cybersecurity Development in the Context of Digital Transformation of Economy and Society
Authors: Yerina Antonina , Honchar Ihor , Zaiets Svitlana
Published: July 2021

Introduction. The scale and destructive consequences of the unlawful impact on cyberspace is a key problem of modern geopolitics, and cyber reliability is recognized as one of the most important security priorities by the subjects of international relations.Problem Statement. Monitoring of cyber incidents and anomalies in information and communication systems and prompt response to risks determined by cyber threats require the development of a system of indicators and criteria for cybersecurity assessment.Purpose. Summarize the international experience of assessing the cybersecurity, to position countries by their level of development in the global space, to identify strengths and weaknesses in cybersecurity management, and to ensure effective protection of cyberspace at the national level.Materials and Methods. Used the component indices of the international rankings characterizing the potential of the digital economy (ICT IDI, NRI, EGDI) and the participation of countries in the field of cybersecurity(GCI and NCSI).Results. It has been argued that cybersecurity ratings play the role of a kind of identifier of the relative advantages and vulnerabilities of the national cyber strategies, and indicate the need for their review in order tostrengthen protection against cyber-attacks and improve the cyber risk management system. In countries with a high level of economic development, which is largely based on the contribution of IT technologies to the national production, the cybersecurity potential is significantly higher, regardless of geolocation. The discovered correlation between GCI, information society development indices (IDI, NRI, EGDI) and GDPper capita confirms that the digital transformation of the economy and society acts as a key driver of economicdevelopment if the information- and cyber-security are assured only. The best practices are highlighted, andcritically weak segments of the national cybersecurity are identified.Conclusions. Using the NCSI indicators, the preparedness of Georgia and Ukraine to prevent the implementation of fundamental cyber threats and to manage cyber incidents and large-scale cyber crises is assessed.
МОЖЛИВОСТІ СТВОРЕННЯ ТА ВПРОВАДЖЕННЯ ВІДКРИТИХ ІННОВАЦІЙ НАУКОВИМИ ОРГАНІЗАЦІЯМИ НАН УКРАЇНИ
Authors: Мельник Марина , Нікітін Ю.О.
Published: July 2021

Вступ. Здатність наукових організацій НАН України швидко створювати й впроваджувати інноваційні науково-технічні розробки має вирішальне значення для прискореного економічного розвитку та є важливим фактором підвищення конкурентоспроможності України.Проблематика. Створення та впровадження інноваційних науково-технологічних розробок може здійснюватися шляхом використання концепції закритих чи відкритих інновацій. Останнім часом посилився негативний вплив низки чинників використання концепції закритих інновацій в діяльності наукових організацій НАН України.Мета. Розробка та апробація удосконалених теоретико-методологічних засад технологічного аудиту науковотехнологічних розробок, оцінки організаційної зрілості та готовності наукових організацій НАН України до застосування відкритих інновацій.Матеріали й методи. Використано підходи теоретичного узагальнення; економічного аналізу та синтезу, математичної статистики, експертного та анкетного дослідження.Результати. Встановлено, що значна частка науково-технологічних розробок наукових організацій НАН Українимає низьку готовність до самостійної та спільної комерціалізації, що характеризує застосування концепції закритих інновацій. Лише частина наукових організацій України має середній рівень організаційної зрілості, а переважна більшість має низький та дуже низький рівень організаційної зрілості та готовності до застосування відкритих інновацій. Натомість застосування зазначеної концепції може сприяти прискореному інноваційному розвитку наукових організацій НАН України. Розроблено теоретико-методологічний підхід технологічного аудиту науково-технологічних розробок та оцінки організаційної зрілості та готовності наукових організацій НАН України до застосування відкритих інновацій.Висновки. Запропонований метод дозволить науковим організаціям НАН України пришвидшити виведення їх на ринки інноваційних науково-технічних розробок.
75 років Лабораторії № 1 Атомного проєкту СРСР
Authors: Шульга Микола Федорович
Published: July 2021

75 років Лабораторії № 1 Атомного проєкту СРСР
Оновлений Статут Академії закріплює її проактивну позицію в державі
Authors: Олег
Published: July 2021

27 травня цього року Загальні збори Національної академії наук України обговорили й затвердили нову редакцію Статуту Академії. Що унеобхіднило внесення змін до головного документа найвищої наукової організації держави і які новації в ньому унормовано, пояснює секретар Комісії з підготовки нової редакції Статуту НАН України, віце-президент НАН України — в.о. головного вченого секретаря НАН України академік Вячеслав Леонідович  Богданов.
Penerapan Contempt Of Court sebagai Terobosan dalam Membangun Efektivitas Eksekusi Riil dalam Perkara Perdata
Authors: Arifardhani Yoyo
Published: July 2021

This study tried to parse the possibility of contempt of court application is a breakthrough to build for effectiveness of real execution of civil cases. The discussion in this study rests on two problem objects, namely; 1) What are the obstacles in the real execution of civil case decisions; and 2) How can a solution be proposed to encourage the effectiveness of the real execution of civil cases. This paper is used to normative legal research so that it rests on the statute approach. The results of this research to indicate that in addition to normative problems in execution arrangements, in practice it is often found that problems occur due to physical resistance from the losing party in the trial. Because of this reason, it is important to apply contempt of court as a legal formulation to create an effective and efficient execution system.Keyword: Contempt of court, Real Execution, Civil CaseAbstrakKajian ini mencoba mengurai kemungkinan Penghinaan terhadap Pengadilan yang merupakan terobosan untuk membangun efektivitas eksekusi nyata dalam perkara perdata. Pembahasan dalam penelitian ini bertumpu pada dua objek masalah, yaitu; 1) Apa saja kendala dalam pelaksanaan putusan perkara perdata; dan 2) Bagaimana solusi yang dapat diajukan untuk mendorong efektivitas pelaksanaan perkara perdata yang sebenarnya. Tulisan ini digunakan untuk penelitian hukum normatif sehingga bertumpu pada pendekatan undang-undang. Hasil penelitian ini menunjukkan bahwa selain masalah normatif dalam pengaturan eksekusi, dalam praktiknya sering ditemukan masalah yang terjadi karena adanya perlawanan fisik dari pihak yang kalah dalam persidangan. Oleh karena itu, penting untuk menerapkan Penghinaan terhadap Pengadilan sebagai rumusan hukum untuk menciptakan sistem eksekusi yang efektif dan efisien. Kata kunci; Penghinaan terhadap Pengadilan, Eksekusi Nyata, Perkara Perdata
Disparities in Childhood Abuse Between Transgender and Cisgender Adolescents
Authors: Thoma Brian C. , Rezeppa Taylor L. , Choukas-Bradley Sophia , Salk Rachel H. , Marshal Michael P.
Published: July 2021

BACKGROUND AND OBJECTIVES

Transgender adolescents (TGAs) exhibit disproportionate levels of mental health problems compared with cisgender adolescents (CGAs), but psychosocial processes underlying mental health disparities among TGAs remain understudied. We examined self-reported childhood abuse among TGAs compared with CGAs and risk for abuse within subgroups of TGAs in a nationwide sample of US adolescents.

METHODS

Adolescents aged 14 to 18 completed a cross-sectional online survey (n = 1836, including 1055 TGAs, 340 heterosexual CGAs, and 433 sexual minority CGAs). Participants reported gender assigned at birth and current gender identity (categorized as the following: cisgender males, cisgender females, transgender males, transgender females, nonbinary adolescents assigned female at birth, nonbinary adolescents assigned male at birth, and questioning gender identity). Lifetime reports of psychological, physical, and sexual abuse were measured.

RESULTS

Seventy-three percent of TGAs reported psychological abuse, 39% reported physical abuse, and 19% reported sexual abuse. Compared with heterosexual CGAs, TGAs had higher odds of psychological abuse (odds ratio [OR] = 1.84), physical abuse (OR = 1.61), and sexual abuse (OR = 2.04). Within separate subgroup analyses, transgender males and nonbinary adolescents assigned female at birth had higher odds of reporting psychological abuse than CGAs.

CONCLUSIONS

In a nationwide online sample of US adolescents, TGAs had elevated rates of psychological, physical, and sexual abuse compared with heterosexual CGAs. Risk for psychological abuse was highest among TGAs assigned female at birth. In the future, researchers should examine how more frequent experiences of abuse during childhood could contribute to disproportionate mental health problems observed within this population.