bluuebunny/crossref_metadata_2025 huggingface dataset:
Acetato de Goserelin (Zoladex) más ablación endometrial para el sangrado uterino disfuncional: Un gran estudio doble ciego, aleatorizado.
Authors: Donnez Jacques , Vilos George , Gannon Michael J. , Stampe Sorensen Soren , Klinte Ingemar , Miller Robert M
Published: May 2020

Objetivo: Confirmar las ventajas del goserelin mas la ablación endometrial para el tratamiento de la hemorra­gia uterina disfuncional.Diseño: Estudio doble ciego, aleatorizado, prospec­tivo, multicéntrico.Pacientes: Mujeres premenopáusicas con ciclos menstruales con sangrado uterina disfuncional.Tratamiento: Las pacientes fueron aleatorizadas a goserelin o placebo (depósito falso) una vez al mes por dos meses antes de la ablación endometrial. El tratamien­to fue calculado para permitir la cirugía 6 semanas después en el día 7 del ciclo menstrual.Medidas principales de resultado: tasas de ameno­rrea, grosor e histología del endometrio, puntajes de dolor y de pérdida de sangre y parámetros quirúrgicos.Resultados: A las 24 semanas después de la cirugía, experimentaron amenorrea, significativamente mas pa­cientes del grupo de goserelin que del de placebo (40% versus 26%). La pérdida de sangre fue menor que la basal, pero sin diferencias entre los grupos. En la cirugía el grosor endometrial fue de 1.6mm y 3.4mm, para los grupos de goserelin y placebo, respectivamente, con glándulas y estroma significativamente mas atróficos en el grupo de goserelin. La cirugía fue significativamente mas corta (en 22%) y mas fácil en el grupo de goserelin que en el de placebo, con una mediana de absorción de líquidos significativamente menor en el grupo de goserelin. En ambos grupos se redujeron los puntajes de dolor, la satisfacción fue alta (>92%) y la tasa de re-­intervención fue baja (2.8%).Conclusión: El goserelin en combinación con la ablación endometrial fue superior a la ablación endometrial sola para el tratamiento de la hemorragia uterina disfuncional.
MOBILIZAÇÃO COLETIVA E TUTELA JURISDICIONAL DO MEIO AMBIENTE: PRINCIPAIS DESAFIOS À LUZ DA CONSTITUIÇÃO FEDERAL DE 1988
Authors: Cortez Bonifácio Artur , Soares dos Santos Jéssyca Cleópatra Yury
Published: May 2020

A presente pesquisa aborda a mobilização da coletividade e sua relação com a tutela jurisdicional do meio ambiente, com ênfase nos desafios democráticos inferidos a partir das normas constitucionais acerca da matéria ambiental. Apresenta a ação civil pública e ação popular como mecanismos judiciais capazes de interferir nos rumos da preservação ambiental. Discute o papel do Estado Constitucional Ecológico, ao estabelecer como premissa sua atuação inserta nos limites estabelecidos pelo Direito Ambiental. Aborda a pluralidade de intérpretes da Constituição, com o intuito de que estes se mobilizem para promover a proteção ambiental. Debate a democracia participativa sob a perspectiva de determinados doutrinadores. Analisa, ainda, as responsabilidades dos legitimados para a proteção ambiental, de forma crítica, ao elencar a ampliação da educação ambiental como um dos desafios democráticos. Utiliza o método dedutivo, uma vez que serão apresentadas noções gerais sobre o tema e, em seguida, uma análise sobre seus aspectos particulares. A pesquisa bibliográfica com a apresentação da perspectiva de diferentes autores sobre o tema foi a metodologia empregada. Percebeu-se que o Judiciário apresenta sobremaneira relevância, em virtude da crise de representatividade atual, bem como nas incertezas vivenciadas na sociedade contemporânea. Concluiu-se que a mobilização coletiva é um desafio, justamente porque não é encontrada em seu formato ideal, aguardando a atuação do Poder Público mediante a formulação de suas políticas.
UNIDADES DE CONSERVAÇÃO AMBIENTAL NO ESTADO DO CEARÁ: IMPLANTAÇÃO E SUSTENTABILIDADE
Authors: Arruda Gerardo Clésio Maia , Fedel Ivone Rosana
Published: May 2020

Este artigo analisa as Unidades de Conservação (UCs) criadas no Estado do Ceará, considerando sua efetividade para a preservação ambiental vis-à-vis a implantação de estratégias de desenvolvimento. Faz-se uma contextualização histórica da trajetória do desenvolvimento econômico relacionando-o aos recursos naturais e a necessidade de sua preservação. Em seguida, explicita-se as obrigações normativas referentes à criação das UCs. Por último, avaliam-se as ações do Estado do Ceará direcionadas ao atendimento das normas vigentes orientadoras da implantação dos Conselhos Gestores e dos Planos de Manejo. Metodologicamente, adotou-se pesquisa bibliográfica e documental, que foi complementada com a técnica de observação direta. Conclui-se que se faz necessária a atuação do Tribunal de Contas do Estado do Ceará, regulamentado para a fiscalização de obras de engenharia e meio ambiente, no sentido de acompanhar a adequação das UCs à Lei do Sistema Nacional de Conservação da Natureza (SNUC), visando garantir a sustentabilidade e conservação do meio ambiente.
MUDANÇAS CLIMÁTICAS E PROJETOS DE PRESTAÇÃO DE SERVIÇOS AMBIENTAIS EM TERRAS INDÍGENAS NO AMAZONAS
Authors: Aily Franco de Camargo Serguei , Oliveira Gomide Plínio Henrique , Rodrigues Lustosa de Camargo Thaísa
Published: May 2020

Devido à seca de 2005, o Amazonas editou a Lei n. 3.135, de 05 de junho de  2007, que instituiu a Política Estadual sobre Mudanças Climáticas. O texto  previu formas de promoção do desenvolvimento sustentável, de manutenção das  condições climáticas e incentivos à participação da população e do Estado na tutela  ambiental. Entretanto, cerca de 10 anos após sua edição, a lei parece ter caído em  desuso. Parte da ineficácia se deve ao desmantelamento da estrutura de Estado  que atuava na implementação de seus instrumentos e parte, em virtude da falta de  regulamentação complementar. Anos depois, o Amazonas editou a Lei n. 4.266, de  01 de dezembro de 2015, que instituiu o sistema de gestão de serviços ambientais  no estado, criou o Fundo Estadual de Mudanças Climáticas e alterou as leis n.  3.135/2007 e 3.184 de 13 de novembro de 2007, que por sua vez, também altera a Lei n. 3.135/2007. Pretende-se assim, avaliar a interação entre todas essas normas, em um amplo exercício de interpretação, com o objetivo de constatar sua eficácia socioambiental. Concluiu-se que a participação das comunidades tradicionais em unidades de conservação de uso sustentável e dos povos indígenas em suas terras, enseja eficácia parcial à Lei 3.135/2007, ao permitir a implementação de projetos de redução das emissões por desmatamento e degradação nessas áreas protegidas, possibilitando o pagamento de recompensas aos prestadores de serviços ambientais.
DIREITO INTERNACIONAL DO MEIO AMBIENTE: PARTICULARIDADES
Authors: Antunes Paulo de Bessa
Published: May 2020

O artigo examina os instrumentos jurídicos disponíveis no âmbito do Di-reito Internacional para a proteção do meio ambiente, buscando demons-trar que existe, em formação, um Direito Internacional do Meio Ambiente, o qual começa a ser afirmar. Ao longo do artigo são analisadas as principais características capazes de marcar a posição peculiar deste ramo em cons-trução da ordem jurídica internacional. Admite-se que o Direito Internacio-nal do Meio Ambiente é um Direito jovem, que, no entanto, vem aportando importantes novidades na ordem jurídica internacional. O artigo destaca algumas de tais modificações, e.g., a modificação dos conceitos de respon-sabilidade e soberania, a ampla utilização de princípios e a transformação gradativa dos sujeitos de Direito Internacional Público. O artigo ressalta, também, as dificuldades políticas, sociais e econômicas para a efetivação e implementação deste novo ramo do Direito Internacional.
A RESPONSABILIDADE CIVIL QUANTO AO DANO AMBIENTAL POR ÁGUA DE LASTRO
Authors: Barbosa Contente Nogueira Caroline , Costa de Lima Cyntia , Paz de Almeida Roger Luiz
Published: May 2020

Este trabalho tem como foco o dano ambiental por águas de lastro, visando compreender a aplicação da responsabilidade civil ambiental nesse tema, observando a complexidade da circulação de bens e de serviços no sistema econômico hegemônico com o potencial de lesão à natureza. Pode-se inferir que a água de lastro é aquela utilizada pelos navios de carga, para equilíbrio e a segurança durante a navegação e que, quando despejada sem a perícia e o cuidado necessários, gera danos ambientais e econômicos irreversíveis. Para isso, foram utilizados os métodos dedutivo, descritivo e analítico, com abordagem qualitativa na realização da pesquisa bibliográfica e documental. As etapas consistiram em breve abordagem da proteção ambiental e sustentabilidade no Brasil, seguida da conceituação e da aná- lise do conceito de dano ambiental e de responsabilidade civil ambiental, para, por fim, trabalhar o conceito de águas de lastro, bem como os possíveis danos e responsabilidade civil ambiental, exemplificando com casos citados ao longo do trabalho. Isto posto, foi possível concluir que os danos ambientais causados pelo deslastre Brasil são de responsabilização civil ambiental de seus agentes, e, solidariamente do Estado, quando comprovada a negligência no gerenciamento e controle do deslastre.
LÍNGUAS, LIVROS E LEIS: O APAGAMENTO DA CULTURA INDÍGENA E RESISTÊNCIA
Authors: Kahmann Andrea Cristiane , Bertoldi Marcia Rodrigues , Figueroa Isabela , Bringuente Ana Carla Oliveira
Published: May 2020

O trabalho propõe uma revisão sobre a formação do Estado brasileiro desde a perspectiva do colonialismo e da colonialidade, orientada pela teoria da decolonialidade, partindo da história das línguas e dos livros em direção à lei e ao apagamento das culturas indígenas. As peculiaridades da colonização brasileira, suas diferenças frente aos países vizinhos latino-americanos e os ecos deste processo no Brasil contemporâneo perpassam os quatro pontos em que se estrutura este trabalho, a saber: (1) a diversidade linguística do Brasil originário e nas mudanças decorrentes do processo de conquista europeu; (2) o processo de independência (política, econômica, cultural) nunca concluído e as sobreposições de dominações que complexificaram as hierarquias, criando dominadores de dominadores e dominados que subjugam a outros dominados; (3) reflexões sobre como os dominadores coloniais mantiveram-se (a si mesmos e à nação) à margem dos ideais de modernidade e racionalidade na perspectiva iluminista; e (4) os ecos do colonialismo e da colonialidade no Brasil contemporâneo sobre as culturas indígenas, especialmente sobre suas línguas, e a resistência dos povos originários. Para tanto, ainda que sejam feitas inferências a partir de dados históricos e estatísticos em abordagem qualitativa, emprega-se o método dedutivo sempre e quando o lugar de fala da autoria referenciada seja equivalente à realidade brasileira. Conclui-se que o reconhecimento do multilinguismo e a participação dos povos originários na tomada de decisões estatais pode permitir que os direitos desses povos passem pela efetivação.
Effects of Various Ameliorants on pH, Phosphorus Availability and Soybean Production in Alfisols
Authors: Triatmoko V. A. , Minardi S. , Widijanto H. , Syamsiyah J.
Published: May 2020

Alfisols have inherent potential to increase Indonesia’s soybean production, however, alfisols also known for its low phosphorus availability. Field experiment using ameliorants consisting of quail manure, zeolites and rock phosphate was conducted to increase phosphorus (P) availability and soybean production. The aim of this study is to evaluate the effects of ameliorant combinations for improving phosphorus availability and its correlation to soybean production in alfisols. Randomized complete block design with single factor was used, with 9 combinations of ameliorants under study (P0 – P8). Obtained results showed that phosphorus availability is increased up to 72.6% and soybean yield upto 75.9%. Correlation of phosphorus availability and soybean production was significant (r = 0.854). Finally, the best treatment to increase phosphorus availability and soybean production is quail manure 2.5 t.ha-1 + rock phosphate 5 t.ha-1).
Evaluation of Relative Efficiency of Alpha Lattice Design and Cluster Analysis of Twenty Spring Triticale Field Experiments
Authors: Abdelkawy R. N.F. , Turbayev A. Z. , Soloviev A. A.
Published: May 2020

Twenty genotypes triticale were evaluated in an alpha lattice design and RCBD for eight characters to a comparison of the relative efficiency (RE) of alpha-lattice design and RCBD. Two experiments were analyzed according to alpha lattice design and RCB design. Average estimated (RE) was 12.97, 5.93, 21.79, 35.50, 21.53, 23.96 and 26.69% for number of plants / m2, tillering fertility, plant height (cm), spike length (cm), number of spikelets / spike, 1000-grain weight (g) and grain yield (g / m2), respectively, the high precision is obtained significantly to estimate treatment effects indicating that using an alpha lattice design in place of RCBD. Mean comparisons for both RCBD and alpha lattice design were performed and two designs confirmed to Dublet, Ulyana, 131/1656 and C259 genotypes were the highest yield (g / m2). Cluster analysis showed that genotypes were isolated into three principle groups and one of these contains one variety (Dublet). This variety was characterized by a high yield over two years. The results showed that alpha lattice more efficient and it can be used it instead of traditional RCB design in the agricultural field trials.
Drybean Yield under the Influence of Cultivar, Phosphorus Fertilizer Rate and Location
Authors: Islam Mirriam , Sebetha Erick
Published: May 2020

The objective of this study was to determine the effect of phosphorus fertilizer rates, cultivar and location on drybean yield production at three different locations of North West province, South Africa. The experimental design was a 5 x 3 x 3 factorial experiment fitted into a randomized complete block design with 4 replications. The three drybean cultivars used were PAN 123, PAN 148 and PAN 9292. Three locations of the study were Taung, Ventersdorp and Mafikeng. The Five levels (0, 1, 2, 3 and 4) of phosphorus fertilizer were applied during planting and these differed according to each location. Drybean cultivar and location had significant effect (P 0.005) on the number of pods per plant, 100- seed mass and grain yield. Drybean cultivar PAN 9292 is recommended for production due to its higher seed yield.
Effects of Durum Wheat (Triticum durum Desf.) Inoculation with PGPR (Azospirillum brasilense, Bacillus sp and Frankia CcI3) and Its Tolerance to Water Deficit
Authors: Benmati M. , Mouellef A. , Belbekri N. , Djekoun A.
Published: May 2020

Plant-growth-promoting rhizobacteria can improve plant growth, development and stress adaptation. However, the underlying mechanisms are still largely unclear. We investigated the effects of Azospirillum brasilense, Bacillus sp and Frankia CcI3 on durum wheat. Our study consisted in the evaluation of the interaction between rhizosphere microorganisms isolated from soils of different regions of Eastern Algeria and two varieties of durum wheat (GTA- dur and WAHA). Furthermore, our studies have also been carried out on the same durum wheat varieties under water deficit condition for the evaluation of the capacities of these PGPR in the restoration of their growth and in the increase of the production. The obtained results confirm the significant abilities of PGPR under these stress conditions for maintaining growth and plant survival.
Photocatalytic Degradation of Herbicide Orthosulfamuron using Zinc Oxide Nanoparticles in Water
Authors: Naveetha Gaggara , Ramesh Atmakuru , Rajasekharam Chirukuri
Published: May 2020

In the present study, the Photocatalysis of Orthosulfamuron, a new class of sulfonyl urea herbicide was investigated using ZnO nano particles in different buffer solutions of pH ranging from 4 to 9. In this study, optimum concentration of the catalyst, initial concentration of the orthosulfamuron and effect of pH of the buffer solution were studied under direct sunlight. The ZnO nano particles were synthesized by sol-gel process and characterized by using SEM, XRD and FT-IR. A commercial formulation of the herbicide having the active strength of 50% was used for the experiment. The rate of reaction followed pseudo first-order kinetics in water. The rate of reaction was 12 folds higher when compared to photolysis. The DT50 values of orthosulfamuron with ZnO nano particles in different buffer solution were 6. 42, 21.68 and 35.22 hours, respectively. The optimum concentration of nano particles to decontamination of orthosulfamuron was observed at 100 mg L-1 and the initial concentration of the orthosulfamuron used in the photocatalysis is 10 mg L-1. The fastest degradation of herbicide orthosulafamuron was observed in pH 4 buffer solution. The degradation products formed during the photocatalysis were identified by using LC-MS/MS which were N-(4,6-dimethoxypyrimidin-2-yl) urea, 2- dimet hyl carbamoyl phenyl sulf amic acid and 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl) pheny lsulfamoyl] urea.
Effect of Temperature and Relative Humidity on the Growth and Development of Acridid Grasshopper, Chrotogonus trachypterus Blanchard
Authors: Meena S. ,  , , Kumari V. , Singh N.
Published: May 2020

Growth and development of acridid grasshopper, Chrotogonus trachypterus Blanchard was greatly influenced by different levels of temperature (20, 25, 30, 35 and 37oC) and relative humidity (40, 60 and 70%). A laboratory study was revealed that temperature between 30-35oC with 60% relative humidity is mostly suitable for life cycle of the test insect. Maximum oviposition period was 54.6±2.21 days at 25oC whereas, maximum hatching percent was recorded at 30oC (90.6±1.18). Average fecundity of a female increased with the increase in temperature up to 35oC (242.1±2.55) but decreased at 37oC. Developmental period of nymphs was longer at 20oC as 94.03±3.45 and 105.3±3.16 days for males and females whereas, nymphs quickly developed at 37oC within 50.3±0.55 and 60.2±2.44 days, respectively. Highest survivability was obtained at 25o and 30oC. Relative humidity ranged from 60-70% gave non-significant differences and found to be most suitable for insect growth. Study of interaction of ecological factors will be helpful in management strategy of the pest and future adaptation behavior and outbreak issues.
Influence of Seed Inoculation Treatments on Yield and Quality of Green Gram (Vigna radiata L.)
Authors: Sharma Priyanka , Borah Prakash
Published: May 2020

To study the effect of seed inoculation treatments with biological agents on seed germination, field emergence and its effect on seed during summer season. Seeds of green gram variety Pratap (SG-1) were treated with microbial formulations of seven treatments which consisted of-Rhizobium (T1), Trichoderma harzianum (T2), Trichoderma viride (T3), Bacillus megaterium (T4), Trichoderma harzianum + Trichoderma viride + Bacillus megaterium (T5), Rhizobium + Trichoderma harzianum + Trichoderma viride + Bacillus megaterium (T6) and Control (T7). Shoot length, root length and seedling dry weight were recorded after 20 days of sowing, observations on nodulation, yield and yield contributing characters were recorded at maturity and germination characteristics of the seeds were studied in the laboratory. It was observed that seeds treated with combined inoculation of Rhizobium @ 4 g + Bacillus megaterium @ 5ml/1000 ml of water + Trichoderma harzianum @ 5ml/1000 ml of water + Trichoderma viride @ 5ml/1000 ml of water (T6) recorded significantly higher field emergence (91.25%), speed of emergence (42.14), seedling dry weight (1.67mg), shoot length (25.48 cm), seed yield (992 kg ha-1), Stover yield (1870 kg ha-1), number of pods plant-1 (37), number of seeds pod-1 (13.25), 100 seed weight (3.63g) root length (9.22 cm) and nodulation (15).
Seed Priming Influences the Seed Quality and Activities of Nitrate Assimilation and Anti-Oxidant Enzymes in Pigeon Pea Seedlings
Authors: Tiwari T. N. , Agarwal D. K.
Published: May 2020

Field experiments were conducted with four levels of seed priming including control and two varieties of pigeon pea at ICAR-Indian Institute of Seed Science, Mau during three consecutive years (2011-12 to 2013-14). One-year-old seeds of pigeon pea varieties (Bahar and Malviya-13) were primed with growth regulator (100 ppm GA3), in-organic salt (0.2% KNO3) and tap water (sanitized) separately for 06 hrs. and sown in field under RBD with 03 replications. Observations were recorded on seed quality parameters, biochemical attributes including nitrate assimilatory enzymes and activities of anti-oxidant enzymes during seedling stage. Seed quality parameters including germination, seedling growth and vigor indices were significantly enhanced through seed priming with GA3 followed by KNO3 and tap water over unprimed control. Biochemical attributes viz; chlorophyll a andb contents, were more influenced with GA3 priming followed by KNO3 and tap water whereas the proline accumulation was reduced with priming treatments and maximum reduction was noted with GA3 followed by KNO3 and tap water. Enhancement in nitrate assimilatory enzymes including nitrate and nitrite reductase activities was more with KNO3 priming followed by GA3 and tap water. Anti-oxidant enzymes activities including Catalase, Peroxidase and Super Oxide Dismutase were also increased significantly by KNO3 priming followed by GA3 and tap water over unprimed control.
Quantitative Detection of Aflatoxin and Species Identification of Aspergillus section Flavi Isolates from Peanuts using Molecular Approaches
Authors: Lavkor I.
Published: May 2020

Totally, 50 Aspergillus section Flavi were identified isolates having aflatoxin biosynthesis genes on peanut by molecular method and aflatoxin production. Primer pair (IGS-F/R) recognized the aflatoxin biosynthesis gene (aflJ-aflR) targeting the intergenic region (IGS) on DNA was amplified by polymerase chain reactions (PCR). The PCR product were restricted by BglII enzyme within Restriction Fragment Length Polymorphism (RFLP) and obtained from 33 (66%) Aspergillus flavus was cleaved into three band sizes of 362, 210 and 102 bp. However, BglII enzyme generated two band sizes of 363 and 311 bp for 17 (34%) Aspergillus parasiticus. An investigation examined DNA sequence data to characterize these isolates and describe the species. Phylogenetic analysis showed that A. flavus and A. parasiticus have been identified in different groups. All the A. flavus and A. parasiticus isolates produced aflatoxins. The present study provides a new method on molecular characterization of A. section Flavi in Turkey.
Competencias investigativas y su influencia en la formulación de proyectos de investigación en la Universidad Valle del Momboy
Authors: Gómez-Escorcha Jesús Antonio , Isea Araque Nicolás , López Lara Verónica de las Mercedes
Published: May 2020

This article aims to establish the incidence of investigative competences in the formulation of research projects in postgraduate students of section A-II, Cohorte 2015, Specialization in Educational Planning of Valle del Momboy University, Barinas municipality, state Barinas, Venezuela. The research was based on the descriptive methodology of field type, the population was conformed by twenty five students and the instrument was the Likert type questionnaire, structured in nineteen items. The results allowed to verify that the theoreticalpractical knowledge that the students had was not pertinent with the elaboration of the research project, just as they did not know the types of competences; basic, methodological and professional. It was concluded that the investigative competences represent a tool that significantly influence the construction of the project and orient the student to play the role of researcher in order to generate epistemological contributions to the field of science
O fim da Teoria da Mídia
Authors: Fazi M. Beatrice
Published: May 2020

Esse artigo considera o papel da teoria em geral e da teoria da mídia em específico. Ao desafiar a possibilidade de um “fim da teoria” que vem ressoando em debates sobre novas mídias, pretendo mostrar a relevância permanente da investigação teórica. Irei abordar como o ato de teorizar é frequentemente compreendido como a criação de um sistema de abstração que envolve certo grau de distanciamento da realidade que deve descrever. Irei posteriormente expor uma falsa concepção em relação a este distanciamento: por exemplo, a visão de acordo com a qual, se teorizar é abstrair a partir da observação, então abstrair é se desengajar dos fatos. Contra essa visão, irei argumentar que a abstração é intrínseca ao mundo e como o experimentamos.
Ethics and cultural identities in different contexts: an interview with Isaac Nahon-Serfaty
Authors: Pieniz Mônica Bertholdo
Published: May 2020

This interview addresses the trajectory and lines of research of professor Isaac Nahon-Serfaty, from the University of Ottawa, Canada. Based on his vast experience as a consultant and researcher, discussions on ethics and cultural identities stand out, especially in the contexts of the work of communication professionals. Themes as health communication, religion and cultural diversity are important parts of this reflection.
Ervilhas congeladas – o prossumidor contemporâneo e a exuberância cosmética dos produtos
Authors: Carrascoza João Anzanello
Published: May 2020

Com a consolidação da cultura de consumo nas últimas décadas, novos agentes da relação entre produção e consumo surgiram, entre os quais o prossumidor – consumidor que é também produtor, uma vez que participa, voluntariamente ou não, do processo produtivo dos bens. Pretendemos, neste artigo, discutir aspectos ligados à “contribuição” do prossumidor no desenvolvimento de produtos, bem como em boicotes virtuais a seus fabricantes, por meio do conto Carta a um fabricante de ervilhas congeladas, da escritora Lydia Davis (2017). Para isso, mobilizaremos conceitos da teoria literária, do processo criativo publicitário e dos estudos sobre sociedade e consumo.
Mapeando o Campo da Comunicação no Brasil: desafios e descobertas metodológicas de uma metapesquisa
Authors: Simões Paula Guimarães , França Vera Regina Veiga , Oliveira Ana Karina de Carvalho , Lima Laura Antônio , Alves Lucas Afonso Sepulveda , Campos Maíra Lobato Bicalho Chagas Moura , Santana Paulo Henrique Basílio
Published: May 2020

O artigo se debruça sobre os desafios de uma pesquisa que mapeia as principais referências teóricas do campo da Comunicação no Brasil, a partir da coleta e do processamento de artigos apresentados entre 2006 e 2015, no evento da Associação Nacional dos Programas de Pós-Graduação em Comunicação. Descrevemos aqui os procedimentos de raspagem das referências teóricas de cada trabalho apresentado em Grupos de Trabalho do evento e as formas encontradas para processar dados textuais através de ferramentas estatísticas, discutindo a articulação entre métodos quantitativos e qualitativos. Por fim, refletimos sobre as descobertas metodológicas de metapesquisa sobre campos científicos. O texto demonstra como a articulação entre procedimentos quantitativos e qualitativos pode ser profícua para o desenvolvimento das pesquisas nas Ciências Humanas e Sociais.
Educación comparada
Authors: Goergen Pedro L.
Published: May 2020

O texto objetivo mostrar do que presente uma das principais causas da situação desalentadora em que se encontra a Educação Comparada no Brasil é a  falta quase total de pesquisas na área. A Educação Comparada foi trazida para cá e incluída nos currículos de nossas instituições de ensino superior. Mas a pesquisa, ao contrário do que acontecia nos centros mais evoluídos, foi relegada a segundo plano. Este fato conduziu a uma desqualificação das disciplinas que passou a ser considerada como uma atividade obsoleta e vista com desinteresse por docentes e alunos da área de educação. Contudo, o desenvolvimento da Educação  Comparada a nível internacional e o rumo internacionalizante da ciência de hoje nos convencem de que o método comparativo pode oferecer contribuição importante à  geração de conhecimentos úteis para a elaboração de políticas educacionais e para a formação dos especialistas em educação. Para que a Educação Comparada se viabilize como uma disciplina útil e produtiva, é necessário renovar a pesquisa na área. Devido às nossas condições limitadas, nos parece conveniente e mais factível orientar essa pesquisa prioritariamente para a realidade latino-americana.
Dijalektika etnodeterminizma
Authors: Hasanović Jasmin
Published: May 2020

Ovim radom ispituje se da li i na koji način politički poredak u Bosni i Hercegovini determiniran logikom etnopolitike sadrži i producira subverzivni potencijal za vlastitu negaciju. Ideja se postepeno javljala u kontekstu različitih protesta u proteklih pet godina, ali se kao naučno pitanje ozbiljnije oblikovalo tek stapanjem protesta “Pravda za Dženana” i “Pravda za Davida” 2018. godine. Kroz proteste se od jedinstvenog matičnog broja i zdravstva preko radničkih prava i demobilisanih boraca kao politiziranih tijela par excellence pa sve do institucionalizirane instrumentalizacije smrti uočava izražena biopolitička dimenzija sa potpisom etnodeterminizma. Politološkim čitanjem odnosa između kontrahegemonijskih narativa odozdo i njihove sve vidljivije kriminalizacije odozdo, autor problematizira kako ono što se ovdje naziva biopolitikom etnodeterminizma producira narativ otpora kao mogućnost koja osvjetljavanjem naličja samog sistema dovodi u pitanje osnovu njegove legitimacije.
Smrtna kazna za otpadništvo u islamu
Authors: Čustović Ajla
Published: May 2020

U članku se sagledava jedna od točaka napetosti u problematici odnosa islama i liberalnog razumijevanja ljudskih prava – sloboda religije naspram smrtne kazne za otpadništvo u islamu. Autorica kritički pristupa ekstremističkom tumačenju islama u kojem se smrtna kazna za otpadništvo prakticira kao jedna od odlika Medinskog ideala – te, preuzimajući Tibijev pojam, odbacuje ekstremističke pokušaje oživljavanja vremena proroka Muhameda kao “izmišljanje tradicije”. Oslanjajući se na progresivnu islamsku misao, autorica toj problematici prilazi iz dvaju smjerova: prvi je smjer preispitivanje izvora smrtne kazne za otpadništvo u Kur’anu i tradiciji proroka Muhameda, a drugi odbacivanje smrtne kazne za otpadništvo kao prakse proturječne ideji ljudskih prava.
Hydroxychloroquine; Why It Might Be Successful and Why It Might Not Be Successful in the Treatment of Covid-19 Pneumonia? Could It Be A Prophylactic Drug?
Authors: Deniz Omer
Published: May 2020

According to current literature and preliminary data, hydroxychloroquine (HCQ) seems potentially effective in the treatment of patients with Covid-19 pneumonia. The concentrations of HCQ in lungs might be well above that of plasma. Most likely, this property of HCQ provides effective drug concentrations in lungs. HCQ has a gradual onset of action in the treatment of rheumatic diseases. This could be valid for the treatment of Covid-19 pneumonia. It was suggested that regular HCQ administration in animals for a certain time might result in gradual accumulation of HCQ in tissues. Reduced perfusion, somewhat distorted architecture of lung tissue, edema and, suggested gradual accumulation of HCQ in lung tissue might cause reduced HCQ concentrations in pneumonic areas of the lungs in Covid-19 pneumonia. Patients with Covid-19 pneumonia and extensive lung involvement might have less HCQ concentrations in their lungs than patients having limited lung involvement. Furthermore, patients with Covid-19 pneumonia and extensive lung involvement might have more viral load than patients having limited lung involvement. That’s why treatment of patients with advanced Covid-19 pneumonia using HCQ might result in treatment failure, however HCQ might be effective in the treatment of patients with mild and moderate Covid-19 pneumonia. Using HCQ in Covid-19 pneumonia prophylaxis seems logical since providing enough accumulation of HCQ in the healthy lungs, before the arrival of the SARS-CoV-2 virus, might prevent Covid-19 pneumonia. However, the purpose of this paper is not to recommend using or not using HCQ for the treatment or for the prophylaxis of Covid-19 pneumonia. The purpose of this paper is only to try to bring a new perspective on the role of HCQ in the treatment or in the prophylaxis of Covid-19 pneumonia. This paper proposes only hypotheses, which need further researches to be confirmed.
Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-Kda Heat-Shock Protein, HspA1A
Authors: Smulders Larissa , Daniels Amanda , Plescia Caroline , Burger Devon , Stahelin Robert V. , Nikolaidis Nikolas
Published: May 2020

HspA1A is a molecular chaperone that plays indispensable roles in cellular survival. HspA1A also translocates to the plasma membrane (PM) of stressed and cancer cells. This translocation results in the cell-surface presentation of HspA1A rendering these tumors radiation insensitive. Thus, a putative therapeutic would be to inhibit HspA1A’s PM translocation. However, to specifically stop the PM translocation of HspA1A, which is lipid-driven, it is imperative to characterize the lipid-binding regions of HspA1A and the relationship between the chaperone and lipid-binding functions of HspA1A, which remain unknown. To elucidate this relationship, we determined the effect of binding to phosphatidylserine (PS) on the secondary structure and chaperone functions of HspA1A. Circular dichroism revealed that binding to PS had minimal alterations on HspA1A’s secondary structure. Measuring the release of inorganic phosphate revealed that PS-binding had no effect on the ATPase activity of HspA1A. In contrast, PS-binding showed subtle but consistent increases in the refolding activities of HspA1A. These observations strongly support the notion that the chaperone and lipid-binding activities of HspA1A are dependent but the regions mediating these functions do not overlap. These findings provide the basis for future interventions to inhibit HspA1A’s PM-translocation in tumor cells, making them sensitive to radiation therapy.
Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors to Drive Pathogenesis of SARS-CoV-2
Authors: Ashray Nancy , Bhide Anshul , Chakarborty Priyanka , Colaco Stacy , Mishra Anuradha , Chhabria Karisma , Jolly Mohit Kumar , Modi Deepak
Published: May 2020

Infection by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) results in the novel coronavirus disease COVID-19, which has posed a serious threat globally. Infection of SARS-CoV-2 during pregnancy is associated with complications like preterm labor and premature rupture of membranes; a proportion of neonates born to the infected mothers are also positive for the virus. During pregnancy, the placental barrier protects the fetus from pathogens and ensures healthy development. However, whether or not SARS-CoV-2 can infect the placenta is unknown. Herein, utilizing single-cell RNA-seq data, we report that the SARS-CoV-2 binding receptor ACE2 and the S protein priming protease TMPRSS2 are co-expressed by a subset of syncytiotrophoblasts (STB) in the first trimester and extra villous trophoblasts (EVT) in the second trimester human placenta. The ACE2- and TMPRSS2-positive (ACE2+TMPRSS2+) placental subsets express mRNA for proteins involved in viral budding and replication. These cells also express mRNA for proteins that interact with SARS-CoV-2 structural and non-structural proteins in the host cells. We also discovered unique signatures of genes in ACE2+TMPRSS2+ STBs and EVTs. The ACE2+TMPRSS2+ STBs are highly differentiated cells and express genes involved mitochondrial metabolism and glucose transport. The second trimester ACE2+TMPRSS2+ EVTs are enriched for markers of endovascular trophoblasts. Further, both these subtypes abundantly expressed genes in Toll like receptor pathway, the second trimester EVTs (but not first trimester STBs) are also enriched for component of the JAK-STAT pathway that drive inflammation. To conclude, herein we uncovered the cellular targets for SARS-CoV-2 entry and show that these cells can potentially drive viremia in the developing human placenta. Our results provide a basic framework towards understanding the paraphernalia involved in SARS-CoV-2 infections in pregnancy.
Why Has COVID-19 Spread More Extensively in Europe than Asia?
Authors: Kenyon Chris
Published: May 2020

It is unclear why European countries have been more severely affected by COVID-19 than East Asian countries. In this ecological study we compared the COVID-19 epidemics (cumulative incidence and mortality rates), host genetic susceptibility and national responses (testing intensity) in all European versus all Western Pacific/East Asian countries reporting cases in the first month of the epidemic. The host-genetic-susceptibility assessment was limited to the frequency of the D-allele of the angiotensin converting enzyme-1 (ACE-1) which has been found to be positively associated with COVID-19 incidence within European countries. Despite earlier epidemics, countries from the Western Pacific reported lower cumulative numbers of COVID-19 cases/100 000 inhabitants than European countries (P=0.0002). The Western Pacific countries also reported fewer cumulative COVID-19 deaths/100 000 (P=0.0024). Whilst there was little difference in the cumulative number of tests conducted/100 000, the percent of COVID-19 tests reported positive was higher in Europe than the Western Pacific (P=0.0076). The frequency of the ACE-1 D-allele was lower in the Western Pacific than European countries (P=0.0007). Our results suggest that a combination of different testing strategies and host genetic susceptibility contribute to difference in severity of the COVID-19 epidemics in the Western Pacific/East Asia and Europe.
A Review on SARS-CoV-2 Virology, Pathophysiology, Animal Models and Anti-Viral Interventions
Authors: Neerukonda Sabarinath , Katneni Upendra
Published: May 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV that is presently plaguing the global human population and economy. No proven effective anti-viral therapy or vaccine currently exist, and supportive care remains to be the cornerstone treatment. Through previous lessons learned from SARS-CoV-1 and MERS-CoV studies, scientific groups worldwide have rapidly expanded the knowledge pertaining to SARS-CoV-2 virology that included in vitro and in vivo models for testing of anti-viral therapies, and randomized clinical trials. In the present narrative, we review SARS-CoV-2 virology, clinical features, pathophysiology, and animal models with a specific focus on anti-viral and adjunctive therapies currently being tested or require testing in animal models and randomized clinical trials.
Investigation of Machine Learning Models and Different Feature Sets for the Efficiency of Early Sepsis Prediction from Highly Unbalanced Data
Authors: Abromavičius Vytautas , Plonis Darius , Tarasevičius Deividas , Serackis Artūras
Published: May 2020

The presented research faces the problem of early detection of sepsis for patients in the Intensive Care Unit. The PhysioNet/Computing in Cardiology Challenge 2019 facilitated the development of automated, open-source algorithms for the early detection of sepsis from clinical data. A labeled clinical records dataset for training and verification of the algorithms was provided by the challenge organizers. However, a relatively small number of records with sepsis, supported by Sepsis-3 clinical criteria, led to highly unbalanced dataset (only 2% records with sepsis label). A high number of unbalanced data records is a great challenge for machine learning model training and is not suitable for training classical classifiers. To address these issues, a number of various models were investigated. A solution including feature selection and data balancing techniques was proposed in this paper. In addition, several performance metrics were investigated. Results show, that for successful prediction, a particular model having few or more predictors based on the length of stay in the Intensive Care Unit should be applied.
Adhesive Hysteresis and Rolling Friction in Rough "Non-Adhesive" Contacts
Authors: Popov Valentin L.
Published: May 2020

In 1975, Fuller and Tabor have shown that roughness can destroy macroscopic adhesion. This means that in spite of the presence of adhesion at the microscopic scale, the macrosopic force of adhesion vanishes. The mechanism of vanishing macroscopic adhesion is very simple: during approach of elastic bodies, asperities are elastically deformed so strongly that after unloading they destroy the microscopic adhesive junctions. However, both in the moment of formation of microscopic adhesive junctions in the loading phase and their destruction during unloading, mechanical energy disappears. This means that the microscopic adhesion makes the contact dissipative even if there is no macroscopic force of adhesion. In particular, the force-distance dependency during indentation and pull-off do not coincide with each other showing some "adhesive hysteresis". When a ball rolls on such rough surface, there will be a final energy dissipation due to formation of a new contact at the frontline of the contact and its destruction at the rear part. Thus, microscopic adhesion will lead to appearance of rolling friction in an apparently non-adhesive contact. In the present paper, we calculate the approach and pull-off dependencies of force on distance, the dissipated energy in one loading-unloading cycle and estimate the force of rolling friction due to microscopic adhesion.
Price Discovery and Market Reflexivity in Agricultural Futures Contracts with Different Maturities
Authors: Volkenand Steffen , Filler Günther , Odening Martin
Published: May 2020

The purpose of this paper is to analyze market reflexivity in agricultural futures contracts with different maturities. To this end, we apply a four-dimensional Hawkes model to storable and non-storable agricultural commodities. We find market reflexivity for both storable and non-storable commodities. Reflexivity accounts for about 50 to 70 percent of the total trading activity. Differences between nearby and deferred contracts are less pronounced for non-storable than for storable commodities. We conclude that the co-existence of exogenous and endogenous price dynamics does not change qualitative characteristics of the price discovery process that have been observed earlier without consideration of market reflexivity.
CHARACTERIZATION OF SOIL THERMAL PROPERTIES FOR DESIGN OF UNDERGROUND CABLE ROUTES AT THE WIND FARM POWER PLANT AREA, PANYIPATAN AND PELAIHARI SUB-DISTRICT, SOUTH KALIMANTAN
Authors: Rasimeng Syamsurijal
Published: May 2020

The estimation of soil thermal resistivity is essential for many types of big engineering projects because of the required knowledge about subsurface transmission of either heated fluids or high power currents. Thermal conductivity measurements were carried out at 12 locations, eight measurement point locations in South Kalimantan, the Sapu Angin hill region, sub-district Penyipatan and four points in the area of Kampung Baru, sub-district Pelaihari made at 2-3 variations in depth of 50 to 100 cm, which adjusted to the ability of the soil drilling support equipment to make holes in the soil. Samples were also collected from the locations for physical parameters description that influences thermal resistivity, subjected to grain size distribution and compaction analysis. The calculation of thermal conductivity is done by using CT-Lab software ver. 1.0.2 with a sensor resistance value of 82.69 ohms / m, heater voltage 4.0 V, and heater power 4.3857 W/m. The results show that the thermal conductivity values range from 0.593 to 3.239 W/mK. For the Sapu Angin hill region, sub-district Penyipatan, soil layers are generally in the form of sandy-clay (λ> 1.2 W/mK), but at some points, the value of thermal conductivity in these layers have decreased (λ <1.2 W/mK) due to rainwater infiltration (BH-02, BH-03, BH-04, BH-05, and BH-07). The infiltration causes weakening or loosening of bonds between the constituent particles of the soil. While in the area of Kampung Baru sub-district Pelaihari, the soil layer is generally in the form of sandy-clay, which has not well compacted (BH-08, BH-10, BH-12) with high water content (BH-09).
A Union Operation of Non-Dominated K-Coterie in Distributed System
Authors: NURHIDAYAH NURHIDAYAH , Lawi Armin , Amir Amir  Kamal
Published: May 2020

Coterie is a set of quorums which has non-empty intersections and are not part of other quorum. The natural development of the coterie system is k-coterie. The k-coterie consists of 2 types, that are non-dominated k-coterie and dominated k-coterie. The non-dominated k-coterie is more resilient to failure than the dominated k-coterie. Combining two non-dominated k-coterie by applying union operation can result  the dominated k-coterie. This study aims to define a combination of the non-dominated k-coterie with non-dominated k-coterie  using the expanded union operation. The merger of non-dominated k-coterie with the non-dominated k-coterie produces a non-dominated k-coterie.
Optimal control for SIR Model with The Influence of Vaccination, Quarantine and Immigration factor
Authors: Agustianingsih Susi , Reorita Rina , Renny Renny
Published: May 2020

The SIR model is one of the mathematical model which describes the characteristic of the spread of infectious disease in differential equation form by dividing the human populations into three groups. There are individual susceptible group, individual infective group, and individual recovered group. This model involves vaccination, quarantine, and immigration factors. Vaccination and quarantine must be given as much as it needs, so a control is required to minimize infection of disease and the number of individual infective with a minimum costs. In this research, optimal control of SIR model with vaccination, quarantine, and immigration factor is solved by using Pontryagin maximum principle and numerically simulated by using Runge-Kutta method. Numerical simulation results show optimal control of treatment, citizen of vaccination, immigrant of vaccination, and quarantine will accelerate the decline of infected number with the minimum cost, compared with the optimal control of SIR model without quarantine factor.
Modeling Claim Frequency in Indonesia Auto Insurance Using Generalized Poisson-Lindley Linear Model
Authors: Karim Mardianto , Mutaqin Aceng Komarudin
Published: May 2020

This paper will discuss the modeling of claim frequency from Indonesian auto insurance using the generalized Poisson-Lindley linear model. This modeling method assumes that the data of claim frequency are from populations that follow generalized Poisson-Lindley distribution. Generalized Poisson-Lindley linear model is an alternative to modeling count data that contains overdispersion. The parameters in the generalized Poisson-Lindley linear model can be estimated using the maximum likelihood estimation method through Newton Raphson's iteration numerical method. The data are the secondary data took from XYZ Company for the 2013 policy which is overdispersed. The data contains policyholder partial loss claims for comprehensive motor vehicle insurance products. From the research conducted it was concluded that the data is suitable to be modeled with generalized Poisson-Lindley linear models and produce better models than ordinary Poisson linear modeling because of produced the smaller AIC value. Of the 3 predictor variables that are modeled on the frequency of claims, 2 variables influenced they are the use variable and vehicle brand variable.