bluuebunny/crossref_metadata_2025 huggingface dataset:
Retrospective study of therapeutic effect of Tongbi paste vs Fufangzhuifeng paste for shoulder periarthritis
Authors: Shixiong Yi  , Jie Zhou
Published: February 2022

Objectives: To compare the therapeutic effects of Tongbi and Fufangzhuifeng pastes in shoulder periarthritis.
Methods: The retrospective study was conducted at the Chongqing Traditional Chinese Medicine Hospital, China, and comprised data of shoulder periarthritis patients who were treated from December 2018 to June 2019. Group A had data of patients treated with Tongbi paste and group B had data of patients treated with Fufangzhuifeng paste. The groups were compared for effect on pain, shoulder flexion, abduction and extension. Data was analysed using SPSS 22.
Results: Of the 81 patients, 43(53%) were in group A; 18(42%) males and 25(58%) females with an overall mean age of 54.26±12.38 years (range: 28-79 years) who were suffering from shoulder periarthritis for a mean duration of 5.08±3.07 months (range: 0.25-13 months). There were 38(47%) patient in group B; 23(60.5%) females and 15(39.5%) males with an overall mean age of 53.08±11.08 years (range: 33-76 years) who were suffering from shoulder periarthritis for a mean duration of 4.96±2.77 months (range: 1-12 months). Mean pain, shoulder flexion, abduction and extension scores after two weeks of treatment were significantly better for group A compared to group B (p<0.001), but after three weeks of treatment, intergroup differences were different but not significant (p>0.05).
Conclusions: Tongbi and Fufangzhuifeng pastes were fund to have a positive effect in the treatment of shoulder periarthritis, with the former providing faster relief.
Key Words: Retrospective study, Shoulder periarthritis, Traditional Chinese medicine.
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Rule Similarity and Axis Symmetry Patterns in Young Patients with Bilateral Astigmatism
Authors: Farrukh Mahmood  , Hina Sharif  , Mahmood Ali
Published: February 2022

Objectives: To report rule similarity and axis symmetry patterns in young subjects with bilateral astigmatism.
Methods: The cross-sectional study was conducted at Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from October 1, 2018, to March 31, 2019, and comprised diagnosed cases of bilateral astigmatism of either gender aged 15-45 years. After giving detailed ophthalmic history, all the participants underwent autorefraction followed by subjective refraction. Based on refractive status, rule similarity was categorised as isorule or anisorule, while axis symmetry was categorised as direct or mirror. Data was analysed using SPSS 20.
Results: Of the 204 participants, 128(62.7%) were males and 76(37.3%) were females. The overall mean age was 26.64±8.44 years. Isorule astigmatism was present in 169(82.8%) participants, while 125(61.3%) had a mirror pattern of axis symmetry. Under the mirror and direct symmetry models, the medians of absolute difference in the axis of fellow eyes were 10 and 5 degrees respectively from exact symmetry. No significant association of rule similarity or symmetry of axis was found with age or gender (p>0.05), while significant association was found between rule similarity and type of astigmatism (p<0.001).
Conclusions: Bilateral astigmatism of isorule category was found in majority of the participants, while mirror symmetry of the axis was more common than direct symmetry.
Key Words: Astigmatism, Axis, Refractive errors, Rule similarity, Symmetry.
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REDUNDANT PUBLICATION – A dilemma of Publication Ethics
Authors: Dr Fatema Jawad
Published: February 2022

The term duplicate or redundant publication was defined by the ICMJE as: “publication of a paper that overlaps substantially with one already published, without clear, visible reference to the previous publication”.1 Redundant publication cannot be ignored by an editor. More in practice in recent times, due to the availability of the electronic gadgets, it is mainly due to the race forpublishing a large number of articles for academic purposes. Lack of time, insufficient research integrity and the competition to achieve more in a short span, makes an author resort to this unethical act. Duplicate submission/publication is “the practice ofsubmitting the same study to two journals or publishing similar contents from the same study in two journals. Thesesubmissions/publications can be nearly simultaneous or years later”.2 Both the practices are very much in use by authors because the disadvantages are either not anticipated or not known. There is also a need of a certain number of publicationsfor their promotion or restrained due to shortage of time for conducting the research and then writing it. Authors indulging in these unethical acts do not anticipate the risks they are undertaking. Detection of such falsified acts, which is very easy, will spoil their reputation, as the matter will be reported to the head of the institution. If the article is published and later retracted due to being a redundant/duplicate publication, the fact will not remain hidden. It could become evident during an interview. In some institutions, unethical acts are given serious consideration and can lead to demotion or barrier to promotion.
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Urban rural differentials in spatial distribution of pregnant women having received Tetanus Toxoid injection by district in Punjab: Results from Pakistan Social and Living Standards Measurements Survey 2014-15
Authors: Masood Ali Shaikh
Published: February 2022

Dear Madam, Tetanus is a potentially fatal infection caused by Clostridium tetani bacteria, and during childbirth it can infect wounds and results in maternal death.1,2 Tetanus Toxoid (TT) vaccination is a simple, effective and freely available preventive measure available in public sector health facilities in Pakistan for pregnant women that can protect pregnant women and their newborns. Globally, TT vaccination is a standard preventive tool in the arsenal of primary health care service providers. In this study, district level TT vaccination coverage in pregnant women during their last pregnancy, in the Punjab province was mapped using Geographic information Systems to highlight its spatial distribution disaggregated by urban, rural residencystatus and the differences between the two types of dwellers.

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Effects of virtual reality exercises and routine physical therapy on pain intensity and functional disability in patients with chronic low back pain
Authors: Afzal Muhammad Waqar , Ahmad Ashfaq , Mohseni Bandpei Mohammad Ali , Gillani Syed Amir , Hanif Asif , Sharif Waqas Muhammad
Published: February 2022

Objective: To compare the effects of Virtual Reality exercises and routine physical therapy on pain and functional disability in patients with chronic low-back pain.
Methods: The single-blind randomised controlled trial was conducted from April to October 2020 at the Physiotherapy Department of the Government Services Hospital, Lahore, Pakistan, and comprised patients of either gender, aged 25-50 years with chronic non-radiating low-back pain who were randomised into two equal groups. Group A received routine physical therapy, while group B received Virtual Reality exercises with routine physical therapy. Visual Analogue Scale and Modified Oswestry Disability Index were used to measure outcomes at baseline and after 4th, 8th and 12th sessions. Data was analysed using SPSS 24.
Results: Of the 84 patients, there were 42(50%) in each of the two groups. There were 28((33%) males and 56(66.6%) females. The mean age in group A was 37.5+12.5 years and in group B it was 38.2+11.8 years. Pain score at baseline was 6.62+1.04 in group A and 6.50+1.24 in group B which decreased to 3.32+0.81 and 1.00+0.60 respectively after the 12th session (p<0.05) . Functional disability score at baseline was 65.08+8.94 in group A and 69.16+9.13 in Group B which decreased to 40.56+8.59 and 16.04+6.82 respectively after the 12th session (p<0.05). Group B showed significantly better results than group A (p<0.05).
Conclusion: Virtual Reality exercises in combination with routine physical therapy had dominant effect on functional disability and low-back pain.
Effect of lumbar traction on discogenic low back pain using variable forces
Authors: Zahra Masood  , Atif Ahmed Khan  , Aisha Ayyub  , Rida Shakeel
Published: February 2022

Objective: To determine the effect of variable traction forces on discogenic low back pain.
Method: The experimental study was conducted at the Department of Physical Medicine and Rehabilitation at the Combined Military Hospital, Okara, Pakistan, from July to December 2018, and comprised patients of low back pain who were randomised into group 1 treated with high-force lumbar traction, hot pack and lumbar stabilisation exercises, and group 2 treated with low-force lumbar traction, hot pack and lumbar stabilisation exercises. There were a 3 sessions per week for 3 weeks for a total of 9 sessions. Modified Oswestry disability index and visual analogue scale were used to measure outcomes. Data was analysed using SPSS 20.
Result: Of the 30 patients, there were 15(50%) in each of the two groups. There were 18(60%) females and 12(40%) males, with an overall mean age of 30+5.5 years. There was significant improvement in pain in both groups (p<0.05), while disability scores in group 1 showed more improvement compared to group 2 (p<0.05). Young age was significantly associated with better results (p<0.05).
Conclusion: Use of variable force lumbar traction improved pain in discogenic low back pain, while high-force lumbar traction also reduced functional disability.
Key Words: Low back pain, Traction, Disability, Exercise, Randomised clinical trial.
Benefits of six week and personalized dosing of pembrolizumab considering ongoing delta variant surge
Authors: Iqbal Arham , Abbasi Zaeem Ahmed , Naeem Fahad
Published: February 2022

Dear sir,
The on-going discussion on fixed dosing or personalized dosing of pembrolizumab has created great chaos among the patients of metastatic non-small cell lung cancer (NSCLC).
Below mentioned are few points in this regard,
Delta variant has affected economies of Asian countries in multiple ways. Personalized and six week dosing of pembrolizumab can be beneficial in this regard. A study conducted by DANIAL A. GOLDSTEIN and co-authors, compared fixed dosing of pembrolizumab with personalized dosing. They have concluded the result that personalized dosing can save upto 24.0% of annual savings in US that is equal to 0.825 billion dollar [1]. These results are supported by another study in which Q6W dosing of pembrolizumab is compared with Q3W dosing. The study states that 400 mg Q6W dosing of pembrolizumab leads to results that are very similar to 200mg Q3W dosing regimen [2]. Another study proposed weight based as well as six weeks dosing of pembrolizumab for the ease of cancer patients [3]. As pembrolizumab is approved for patients with stage III resected melanoma therefore delaying its therapy may have similar effects on overall survival [4].
Keeping all these point in view we would like to suggest that it would be better if doctors from now onwards suggest Q6W dosing of pembrolizumab instead of Q3W dosing as well as personalized dosing should be promoted as compared to fixed dosing as this well help in lowering down the financial as well as health burden on patients with metastatic non-small cell lung cancer (NSCLC).
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Rare complication mimicking Kawasaki disease among children infected with COVID-19: A heads-up for paediatricians
Authors: Nitik Sharma  , Arsalan Hyder  , Sikandar Ali
Published: February 2022

Dear Madam,
We are amidst a pandemic of coronavirus disease of 2019 (COVID-19) that began in late 2019 and has quickly spread worldwide. It has a wide diversity of clinical features in adults and life-threatening complications in people with underlying co-morbidities. For reasons not completely understood, the paediatric population infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents with less severe clinical symptoms when compared to the adult population [1]. In April 2020, a mysterious hyper-inflammatory syndrome mimicking Kawasaki disease (KD) appeared in children that came about as sequelae of SARS-CoV-2 infection and termed multisystemic inflammatory syndrome in children (MIS-C) [2]. MIS-C, otherwise known as "paediatric inflammatory multisystem syndrome temporarily associated with severe acute respiratory syndrome coronavirus 2" (PIMS-TS), manifests with a wide variety of clinical features, a few of them found among these children are a fever that lasts for more than 3-4 days, mucocutaneous involvement such as conjunctivitis and rash and gastrointestinal symptoms like diarrhoea and vomiting [2]. One of the feared complications of MIS-C is multi-organ dysfunction, with cardiovascular being the frequent one.
Recently, a new strain of SARS-CoV-2 called (Delta) variant, also known as lineage B.1.617.2, has paved its way into Pakistan [3]. This variant produces a high amount of viral load and is twice as contagious as the original strain of SARS-CoV-2 [4]. Although there are currently no studies showing increased risk of developing MIS-C associated with this variant, the high transmission rate puts the paediatric population at increased risk of contracting the virus. The signs and symptoms of this syndrome overlap with many other bacterial and viral childhood illnesses making it difficult to diagnose. Therefore, the world health organization (WHO) has prepared a preliminary case definition that characterizes the clinical patterns that include duration of fever, serum markers of inflammation and evidence of prior infection with SARS-CoV-2 to better identify and start early interventions for this syndrome [5]. A report from Italy revealed a staggering 30-fold rise in KD like cases in children during the outbreak of COVID-19 [6].
As the new exceedingly contagious strain of (Delta) variant is on the rise in Pakistan, there is a high chance that the number of children with COVID-19 related MIS-C may escalate. In summary, children presenting with unexplained fever, rash, and contact history with a COVID-19 infected should be suspected of MIS-C and treated accordingly with the guidelines provided by WHO.
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Kesediaan Murid Mengaplikasikan Pengendalian Google Classroom Sebagai Alat Media Interaktif dalam Pembelajaran Matematik
Authors: Devar Anbalagan , Maat Siti Mistima
Published: February 2022

Kajian ini berbentuk tinjauan untuk menyiasat sama ada pelajar bersedia untuk menggunakan Google Classroom sebagai media interaktif untuk pengajaran dan pembelajaran matematik. Penyelidikan ini menggunakan teknik persampelan rawak mudah, dan sampel kajian adalah seramai 110 orang pelajar darjah 5. Keputusan menunjukkan bahawa pelajar berada pada tahap persediaan pertengahan untuk menggunakan Google Classroom. Penyelidikan ini juga membuktikan bahawa dalam proses membantu pelajar dan guru mempelajari matematik, tidak terdapat perbezaan yang signifikan dalam purata tahap persediaan untuk mengaplikasikan Google Classroom dari segi jantina, pengetahuan, motivasi dan sikap.
Green Finance: The Future of Sustainable Banking in India
Authors: Rout Sanat , Sahoo Sadananda
Published: February 2022

India is now in a situation where it has to accept the challenges from the international forum to improve its green infrastructure and attain its sustainable developments goals and climatic challenges like global warming, its huge population and huge green depletion. If the country has to survive it has to adopt Green finance. Green finance or climate finance is a component where it has to change it’s focus and behaviour from traditional form of financing to more environment friendly financing. It has to build a strategy through green finance to achieve its sustainable development goals. Indian and international financial agencies, corporates need to be encouraged to refocus on the aspect of green finance. There has been lot of promises and challenges in this front. This study is an effort to understand the situation where India stands and the go ahead as far as green finance and to manage its sustainable development goals. This study is of descriptive in nature and is based on secondary data derived from various international and national agency reports, which includes report from Government of India.
The Influence of Covid – 19 on Virtual Employee Management Practices by Organisations: An Empirical Study
Authors: Nagaria Smriti , Kareem Midhat
Published: February 2022

In the mid of 2020, the COVID– 19 disease began rapidly disrupting lives, economies, and workplaces and continues to do so. It was when the disease was brought in a global debacle it forced the world to go into complete lockdown with strict government guidelines of social distancing. The pandemic resulted in the loss of jobs and high rate of unemployment. The COVID – 19 plagues forced organizations to make rigorous changes to the workplace leading to complete chaos to employee and employer experience. One of the most drastic changes was “Work from Home”. The human resource management department was forced to come up with new strategies to face the challenges of remote working. Scholars including Snell et al. (2002) and Ulrich et al. (2017) have argued the relevance of a strategic HR approach during such challenging times as essential in ensuring institutional competitiveness. Accordingly, institutions turned their attention to virtual employee management (VEM) as an alternative to the traditional system of employment management. According to Henderson et al. (2016), at the time, the adoption of Virtual Employee Management becomes mandatory to facilitate collaboration across isolated employees and stakeholders. Virtual Employee Management is co-dependent groups who work from the comfort of their places with the help of virtual tools or apps like Zoom, Skype and Google meet to communicate work. The major responsibility lies in making productive ‘remote teams’ a crucial challenge for human resource managers. A survey was conducted on 50 employees and lecturers from esteemed universities by providing them a questionnaire. Remote team leaders’ constant hurdles were managing projects, lack of team communication technology issues at home, geographical and cultural barriers. The virtual employee faced core challenges such as overworking after work, maximizing productivity, overcoming distractions and staying motivated. This paper is an empirical paper presenting the problems being faced in virtual employee management by the influence of COVID -19 in general and provides strategies to overcome them to face this epidemic.
Knowledge, Attitudes, and Practices on Pesticide among Farmers in the Philippines
Authors: Lu Jinky Leilanie
Published: February 2022

Introduction. Pesticides are widely used in the agricultural sector to increase production by cutting down costs and improving the quality of produce. However, these chemicals come with serious health effects when an individual is exposed to large quantities at once, or low quantities over time.

Objectives. The objective of the study is to investigate the knowledge, attitude, and practices of farmers, as well as investigate the correlation among knowledge, attitude, and practice variables.

Methods. This research study used a cross-sectional design. Samples were drawn based on a multistage sampling of 387 agricultural workers. The target site was in Southern Philippines and the sample was selected using multi-stage sampling from the identified municipalities. Survey questionnaires were given to the respondents to measure knowledge, attitude, and practices (KAP) on pesticide exposure among farmers. The data were encoded using SPSS 13.0. The statistics used were both descriptive and inferential. Correlation analysis was used to study the relationship among knowledge, attitudes, and practices.

Results. The results showed that farmers used pesticides in their farms on an average of 2.31 days per week (SD 2.13). The respondents reported that they were exposed to pesticides for about 3.46 months per cropping season (SD: 2.76), as well as from 3.34 (SD 5.92) cropping seasons per year. The mean score of the respondents on the knowledge aspect of the questionnaire was 5.91 out of 10 items (SD 3.28). The average score on practices on pesticide use among respondents was 3.37 (SD 1.75) with 8 items to evaluate practices. Lastly, the mean score on attitude on pesticide use among respondents was 5.34 (SD 3.31) over 12 items. Analysis showed a moderate correlation between knowledge and attitude with Pearson’s r = 0.651 (P <0.0001), also a moderate correlation between knowledge and practices at r = 0.521 (P <0.0001), and a moderate correlation between practices and attitudes at r = 0.443 (P <0.0001). Factor analysis revealed three components for items within practices and attitudes and two for items within knowledge.

Conclusion. Pesticide use in the Philippines continues to present various challenges in terms of its safety to humans and the environment. Farmers do not have adequate knowledge of pesticides and their proper management from use to disposal. They need to improve knowledge, encourage a healthy and safe attitude and correct practices on the hazards from pesticides, as well as its proper usage and handling. It is recommended that capacity building and training for farmers are initiated to address inadequacies in their knowledge, attitudes and practices.
Road Traffic Injuries among Women Brought to the Largest Tertiary Hospital in the Philippines
Authors: Lu Jinky Leilanie , Lu Sophia Francesca D.
Published: February 2022

Introduction. Road traffic accidents are a growing public health burden, especially in the low- and middle-income countries (LMICs). With resource scarcity, road traffic injuries may lead to poor quality of life among survivors, or deaths at worst. Victims of crashes involving transportations are gendered; therefore, there may be differences in the trends and characteristics of injuries sustained by men and women related to road crash.

Objectives. This study aimed to determine the factors related to severity of road crashes among women road users in the Philippines from 2008 to 2017.

Methods. We conducted a retrospective review of clinical records of women patients involved in road crash at the Trauma Division, Department of Surgery of the Philippine General Hospital (PGH) for the ten-year period, January 1, 2008 to December 31, 2017. Data were extracted from the electronic patient records in Integrated Surgical Information System (ISIS).

Results. From 2008 to 2017, 926 of the road crash victims brought to PGH were women. There was an increasing trend, with the years 2015 to 2017 accounting for half of the total cases (55.62%). The highest cases of women patient admissions were also recorded during the months of June and July (5.61%). The CALABARZON region (11.23%) and National Capital Region (8.21%) had the highest admissions. The patients were most commonly pedestrians (12.20%) and involved in collisions (13.50%) or vehicle involvement (13.17%). The most common vehicle involved was a motorcycle (9.72%) followed by car and vans (1.62%). Only a small proportion of women patients used helmets (3.33%) and seatbelts (0.12%). The median length of hospital stay of women patients was 5 days. The most commonly sustained injuries among patients were multiple (83.65%), external (43.72%), extremity (33.15%), head and neck (23.47%), and face (21.58%) injuries. Among these, injuries to the extremity had the highest average length of hospital stay (16.04 ± 31.28 days) while external and head and neck injuries had the shortest (10.81 ± 33.42 days). Multinomial regression showed that women patients who suffered from head and neck, and abdominal injuries had increased odds of dying by 4.94 times (CI: 2.158-11.302, p < 0.05), and 3.33 times (CI:1.235-9.02, p < 0.05), respectively, compared to those who did not suffer said injuries.

Conclusion. There is a significant number of women involved in road crashes in the Philippines, and therefore, there is a need for directed policies on female road users as vulnerable road users.
Optimal Category Mix in Multi-Category Retailing – Insights from an Experiment
Authors: Ganesh H.R. , Aithal P. S. , P. Kirubadevi
Published: February 2022

In brick-and-mortar retailing format, retailers need to ensure minimum level of inventorydisplayed at each store for each category irrespective of the revenue or profit generated by aparticular category. It is observed that majority of bricks-and-mortar retailers in India assume;(a) existing category mix is ideal for their stores, (b) any modification in the existing categorymix could possibly lead to loss of sale of an existing category, (c) it is preferred to havecategories generating higher average transaction values and most importantly,(d) categorieswith lower average selling price products and generating lower average transaction valuesnegatively impact store’s revenue. Such assumptions and widely followed practice havecreated a predisposition and mindset in store managers and they believe that, their storedelivers revenue and profit to the best of its potential with the existing category mix. In thisresearch, we have analysed the existing category mix of a select retailer, attempted to alter theexisting category mix through an experiment and evaluated change in (a) category levelprofitability, and (b) overall store profitability.
LA CRÍTICA HACIA LA INMOVILIDAD CULTURAL DE CHILE, EN UN AÑO DE JUAN EMAR
Authors: Lee Kakyung
Published: February 2022

La novela de Juan Emar, Un año, consta de doce episodios que ocurren, o al menos se registran, en el primer día de cada mes del año. Este análisis se enfoca en la furia que siente el narrador-personaje en los meses de mayo, junio y julio. Se propone que la furia del narrador-personaje reflejaría la frustración de Juan Emar como miembro de una élite vanguardista en la sociedad apática y tradicionalista de Chile. El análisis considera los siguientes puntos, con atención especial al contexto sociopolítico de la obra: Juan Emar es un artista de la vanguardia dentro de Chile, en los años veinte del pasado siglo; la furia está dirigida a las instituciones sociales, a la sociedad en sí y a la élite chilenas; el insecto que aparece en mayo representaría la incapacidad del narrador-personaje para cambiar el ambiente cultural de Chile.
FICÇÃO-CRÍTICA E VIDA LITERÁRIA NOS ROMANCES "EM LIBERDADE" E "MACHADO", DE SILVIANO SANTIAGO
Authors: Rocha Helder Santos
Published: February 2022

Este artigo apresenta uma análise de dois romances de Silviano Santiago, o Em liberdade (1981) e o Machado (2016), com ênfase na discussão ética e estética da imaginação de cenas da vida literária brasileira de outros tempos, que recontextualiza arquivos e ressignifica personagens da história cultural. A análise está baseada na noção de ficção-crítica (WEINHARDT, 2011), mas, também, amparada nos ensaios de Barthes (2007) acerca do entrelace discursivo entre as práxis literária e crítica desde a década de 1960 em cenário francês, além das reflexões em torno da ficção histórica contemporânea na América Latina que dialogam diretamente com a problemática da globalização e do neoliberalismo (PERKOWSKA, 2008; AÍNSA, 2003). Conforme análise e cotejo da sobras, percebe-se que, na impossibilidade de desocupar os lugares e as funções de ficcionista e de crítico, o intelectual Silviano Santiago se utiliza da narrativa híbrida para falar de si e dos outros, da literatura e da vida, como forma de alargamento dos campos estético e político.
PER-MANHECER SELVAGEM: MULHER ESQUELETO, YKAMIABAS E GINGA
Authors: Borges Lígia de Moura
Published: February 2022

Este artigo circunda o sopro da narradora, fundamento da sua vocalidade poética ao dirigir um olhar para a questão de gênero na arte de contar histórias. Ensaia uma escrita rapsódica entrelaçando pensamento e narrativa, ficção e realidade e assim, aborda o confronto entre tradição e ruptura. Primeiramente em uma fonte fundamental nessa arte: os Contos Tradicionais do Brasil de Câmara Cascudo com uma perspectiva de estranhamento. Então segue na busca de sopros selvagens em contraponto à ideia de domesticação a partir de Clarissa Pínkola Estés e da narrativa “Mulher Esqueleto”, de visões acerca do mito das Ykamiabas e da Rainha Ginga.
UMA LEITURA DAS TRADUÇÕES CUBANA E ARGENTINA DE 'QUARTO DE DESPEJO' SOB A PERSPECTIVA DA CRÍTICA FEMINISTA DECOLONIAL DE TRADUÇÃO
Authors: Chaves Bruera Penélope Serafina
Published: February 2022

Este trabalho visa indagar nas traduções ao espanhol de Quarto de despejo de Carolina Maria de Jesus do século XX, Quarto de despejo, diario de una mujer que tenía hambre publicada em 1961 na Argentina e Favela publicada em 1965 em Cuba. Ambas são examinadas sob a perspectiva da crítica feminista de tradução, com o objetivo de visibilizar como raça, classe e gênero conformaram um entramado estreito e indissolúvel que condicionou tanto a recepção da autora na América Latina e o Caribe, quanto o tratamento que os/as tradutores/as deram a sua obra. Para isso, apresentamos brevemente a conjuntura editorial de cada caso e depois analisamos detidamente os paratextos elaborados pelos/as tradutores/as. Por fim, chamamos a atenção às observações dos/as diversos/as agentes literários implicados, que insistiram em remarcar a ‘importância sociológica’ da obra, reproduziram os erros gramaticais do texto fonte e, em consequência, se empenharam em apagar as escolhas estéticas da autora que correspondiam à linguagem da literatura clássica.
Use of Sugarcane Bagasse ash to Manufacture Light Weight Sustainable and Economical Concrete
Authors: Alka A. Avasthi  , Prasad Joshi  , Sampat Nanaware  , Pratibha Patil  , Vijeta Kundlikar
Published: February 2022

Sugarcane bagasse ash is the admixtures used in this study. As we are an agricultural country and we harvest at least two crops yearly. These two crops are harvested every year and the yields produce a lot of waste in the form bagasse. This produces around at least 20 to 30% of waste of the total yield. Traditionally this waste is disposed off by burning it in the open fields. This acts as a fertilizer for the next crop, but it has a very bad effect on the environment as the smoke generated increases the air pollution. Hence using this material as partial replacements to cement will not only prevent open field burning but will also reduce the cement consumption. The density of sugarcane bagasse ash is lesser than cement and hence reduces the weight of the concrete manufactured using this as partial replacement to cement[1]. There are lot of research studies about manufacturing of light weight concrete using light weight aggregates[2]. Hence in addition to the light weight aggregates if light weight mineral admixtures are also used they will further reduce the weight of concrete thus leading to reduction in self weight of the structure. Hence including sugarcane bagasse ash in concrete as partial replacement to cement will not only reduce and recycle the waste but will also produce an economical, sustainable and light weight concrete mix.
Social Determinants of Health and its Role in Headache Disorders
Authors: Peres Mario Fernando Prieto , Valença Marcelo Moraes , Andrade Juliana Ramos , Santos Erlene Roberta Ribeiro
Published: February 2022

Editorial
Oxytocin, vasopressin and nitric oxide levels in cerebrospinal fluid in women with migraine and fibromyalgia (Abstract)
Authors: Lima Louana Cassiano da Silva
Published: February 2022

Abstract: Thesis (Doctorate in Neurosciences). Postgraduation in Neuropsychiatry and Behavioral Sciences. Federal University of Pernambuco, Recife, Brazil. 2017. 86 f. Supervisor: Prof. Dr. Marcelo Moraes Valença.
Prevalência de diagnóstico e principais comorbidades em crianças e adolescentes com cefaleias primárias e secundárias atendidas no setor terciário
Authors: Silva Nathiely Viana , Pradela Juliana , Dach Fabíola , Bevilaqua-Grossi Débora
Published: February 2022

Introdução

As cefaleias primárias e secundárias atingem em torno de 60% das crianças e adolescentes, e cerca de 80% deles possuem comorbidades.

Objetivo

Avaliar a prevalência de diagnóstico e comorbidades de crianças e adolescentes com cefaleias atendidos em um hospital terciário nos últimos cinco anos.

Material E Métodos

Estudo retrospectivo, baseado na revisão de prontuários de crianças e adolescentes atendidas no Ambulatório de Cefaleia Infantil localizado no HCFMRP/USP entre os anos de 2016 e 2021. O estudo foi aprovado pelo Comitê de Ética em Pesquisa Local (CAAE: 45631321.0.0000.5440). Os pacientes foram classificados de acordo com a idade, como crianças (CR; <12 anos) e adolescentes (AD; 12 a 18 anos). As comorbidades apresentadas foram classificadas de acordo com o tipo de doença. Os dados foram analisados utilizando o programa Microsoft Corporation® Excel. 

Resultados

Foram analisados 242 prontuários, sendo que 54% da amostra eram crianças (8,7 anos, DP 2,0) e 46% adolescentes (14,4 anos, DP 1,8). Os indivíduos foram diagnosticados com migrânea (CR 80,7%; AD 74,2%), cefaleia tensional (CR 2,3%; AD 1,8%) e cefaleias secundárias (CR 6,2%; AD 6,8%). Pacientes com mais de um diagnóstico foram classificados com cefaleia mista (CR 4,6%; AD 12,6%), e aqueles sem diagnóstico definido, com diagnóstico inconclusivo (CR 6,2%; AD 4,6%). As principais comorbidades observadas nas crianças foram distúrbios do sono (25,6%) e doenças respiratórias (23,3%), como a rinite. Já em adolescentes, além das doenças respiratórias (23,1%) e distúrbios do sono (19,8%), as doenças neurológicas (23,1%) como a epilepsia, também foram altamente prevalentes.

Conclusão

A prevalência de migrânea se destaca tanto em crianças quanto em adolescentes. Quanto às comorbidades, as doenças respiratórias e os distúrbios do sono foram comuns em crianças e em adolescentes, e doenças neurológicas apresentaram alta prevalência apenas entre os adolescentes.
Influência da presença de hábitos orais parafuncionais em vigília em indivíduos com disfunção temporomandibular dolorosa associada ou não a cefaleias
Authors: Spavieri Juliana Homem Padilha , Anjos Deise Isabela Moreira dos , Braido Guilherme Vinicius do Vale , Proença Juliana dos Santos , Gonçalves Daniela Aparecida de Godoi
Published: February 2022

A disfunção temporomandibular (DTM) é uma condição musculoesquelética e neuromuscular de etiologia multifatorial. Está frequentemente associada à comorbidades dolorosas (cefaleias primárias, por exemplo) e à cefaleia atribuída à DTM (cDTM). Hábitos orais parafuncionais em vigília (HOV) podem influenciar essas condições dolorosas, piorando o prognóstico e aumentando a refratariedade ao tratamento. O objetivo deste estudo transversal foi investigar a associação entre DTM, HOV, migrânea (Mg), cDTM e sintomas de depressão e ansiedade. A DTM foi classificada de acordo com o RDC/TMD, as variáveis sociodemográficas foram classificadas de acordo com os critérios do IBGE, a presença e frequência de HOV, os sintomas de depressão e de ansiedade foram coletados por meio de questionário. A Mg foi identificada de acordo com os critérios da Classificação Internacional de Cefaleias – 3ª. Edição, e a cDTM de acordo com os critérios de Schiffman et al. (2014).  A amostra, composta por 117 indivíduos com 20 a 65 anos de idade, foi estratificada em 4 grupos para estudos de associação: Controles; DTM; DTM+Mg; DTM+Mg+cDTM. As mulheres apresentaram DTM e cefaleias com maior frequência que os homens (p<0,001). Houve associação significante entre maior grau de incapacidade relacionada à dor crônica da DTM e os grupos (p<0,0001). A regressão logística multinomial apontou que na presença de maior frequência de HOV, os indivíduos tinham maiores chances de ter as 3 condições dolorosas simultaneamente (Odds Ratio (OR)=3,23; IC = [1,06-9,81]. O hábito de apertar os dentes em vigília aumentou as chances de os indivíduos apresentarem DTM+Mg e DTM+Mg+cDTM (OR=1,81; IC= [1,25-2,64]). Os resultados demonstram que a presença e a frequência dos HOV podem interferir na relação entre a DTM e as cefaleias, piorando o prognóstico e aumentando a chance de comorbidade entre estas patologias.
Preditores de hiperacusia na migrânea
Authors: Maistro Bruna Colomera , Machado Ana Clara Oliver , Bossa Beatriz Bagatim , Bello Valéria Aparecida , Frederico Regina Célia Poli , Silva Aline Vitali da
Published: February 2022

Introdução

A fonofobia é um sintoma comum e compõe o critério diagnóstico de migrânea, no entanto a hiperacusia ainda foi pouco estudada no contexto da migrânea.

Objetivo

Avaliar a prevalência e os preditores de hiperacusia em pacientes com migrânea. 

Metodologia

Estudo prospectivo do tipo caso-controle composto por pacientes com migrânea. Os participantes responderam entrevista estruturada sobre dados demográficos, antropométricos e características clínicas da migrânea. Também responderam questionários validados sobre depressão (IDB), ansiedade (STAIY2), incapacidade (MIDAS), alodinia (ASC-12) e ao questionário de hiperacusia. Foi considerado que o participante tinha hiperacusia quando tivesse pontuação ≥22 no questionário de hiperacusia. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa (n° 3.029.972). 

Resultados

O questionário foi respondido por 276 pacientes com migrânea, dos quais 237 do sexo feminino, 171 com migrânea episódica e 106 com aura. Em análise univariadas a hiperacusia foi associada a migrânea crônica (OR=2,28; p=0,001), fonofobia (OR=2,56; p=0,017), osmofobia (OR=2,97; p<0,001), alodinia (OR=2,91; p<0,001), ansiedade (OR=10,57; p=0,007), depressão (OR2,89; p=0,002) e incapacidade relacionada a migrânea (OR=2,81; p=0,002). Após regressão logística binária, permaneceram associados a hiperacusia: a forma crônica da migrânea (OR=2,03; p=0,019), osmofobia (OR=2,2; p=0,022) e maior incapacidade relacionada a migrânea (OR=2,5; p=0,022). Idade, gênero, obesidade, aura e fotofobia não se associaram a hiperacusia.

Conclusão

A forma crônica, osmofobia e maior incapacidade foram preditores de hiperacusia em indivíduos com migrânea.
Associação entre alodinia cutânea e frequência, intensidade e duração da migrânea na população pediátrica – estudo piloto
Authors: Santos Michelle Aparecida Anjos , Pradela Juliana , Dach Fabíola , Bevilacqua-Grossi Débora
Published: February 2022

Introdução

A migrânea afeta 9,1% de crianças e adolescentes e pode ocasionar crises de curta duração, intensidade variável, podendo ser crônica ou episódica. Embora o processo de sensibilização central seja conhecido na migrânea, ainda não está estabelecida a relação entre a alodinia cutânea e as características da crise em crianças e adolescentes. 

Objetivo

Avaliar a associação da alodinia cutânea com as características da migrânea na população pediátrica.

Métodos

Este é um estudo piloto, com desenho transversal, que avaliou 17 pacientes com migrânea (12,1 anos, DP 3,2) de ambos os sexos, recrutados no Ambulatório de Cefaleia Infantil do Hospital das Clínicas de Ribeirão Preto. Os pacientes preencheram um questionário estruturado sobre a frequência, intensidade e duração da migrânea, e em seguida responderam ao Questionário de Alodinia baseado no ICHD-III versão beta (adaptado), composto por 4 questões que avaliam a presença ou ausência da alodinia cutânea durante crises de migrânea. Pacientes que apresentaram pelo menos duas respostas positivas foram classificados com alodinia cutânea. O estudo foi aprovado pelo Comitê de Ética em Pesquisa (CAAE 31864020.0.0000.5440). A correlação de Spearman (p<0,05) foi aplicada para avaliar a associação entre as variáveis. 

Resultados

A alodinia cutânea foi observada em 53% dos pacientes. Todos os participantes apresentaram migrânea episódica (frequência 3,0 dias por mês; DP 2,3), intensidade de dor leve (2,2; DP 0,7) e curta duração (5,4 horas; DP 5,2). Não foram observadas correlações significativas entre a presença de alodinia e a frequência (rho=0,01; p=0,96), intensidade (rho=0,37; p=0,13) e duração (rho= -0,02; p=0,92) das crises de migrânea. 

Conclusão

Os dados deste estudo piloto sugerem que a alodinia cutânea não está associada com a apresentação clínica da crise migranosa em crianças e adolescentes.
Monitorização não invasiva da pressão intracraniana em pacientes com queixa de cefaleia: série de casos
Authors: Cherain Luiz Gabriel Gonçalves , Barbosa Mateus Gonçalves de Sena , Francisco Ghaspar Gomes de Oliveira Alves , Frigieri Gustavo , Rabelo Nícollas Nunes
Published: February 2022

Introdução

O aumento da pressão intracraniana (PIC) constitui um conjunto de sinais e sintomas relacionados à alteração do volume e da pressão intracraniana, essas alterações são visíveis em diversas doenças neurológicas, o que inclui a cefaleia. Em pacientes com cefaleia crônica a monitorização da pressão intracraniana é realizada de maneira não invasiva o que traz menores danos ao paciente e rapidez nos resultados. O objetivo deste trabalho é elucidar como a monitorização não invasiva da pressão intracraniana em pacientes com cefaleia é realizada e as conclusões a partir da monitorização.

Metodologia

Estudo de série de casos retrospectiva, onde foram coletados dados clínicos de 32 pacientes atendidos em consultório entre dezembro de 2020 a setembro de 2021, com cefaleia (exceto do tipo enxaqueca), sem restrição de sexo, idade, cor, raça e nível socioeconômico. Todos foram submetidos a monitorização não invasiva da pressão intracraniana por um dispositivo da Brain4care. 

Resultados

Dos 32 pacientes analisados, foi observado que a relação P2/P1 teve seu valor aumentado, com uma média de valores de 1,15 (0,82-1,62). O time to peak teve uma média de 0,23 (0,04-0,34). Esses dados tendem a indicar um aumento da pressão intracraniana e uma diminuição na complacência cerebral em pacientes que relataram queixa de cefaleia. A monitorização não invasiva é importante pois possibilita as medições no consultório, fora do ambiente hospitalar. 

Conclusão

O dispositivo de monitorização não invasiva mostrou uma relação entre o aumento da PIC e a queixa de cefaleia. A vantagem é que a medição pode ser realizada no consultório, utilizando a tecnologia a favor da segurança e conforto do paciente.
Perfil Clínico e Epidemiológico de Universitários com Migrânea Durante a Pandemia COVID19
Authors: Alcylene Carla de Jesus dos  Santos  , Acássia Benjamim Leal  Pires  , Ana Patricia Pascoal  Queiroz  , Luana de Oliveira  Leite  , Maria da Glória Canto de  Sousa
Published: February 2022

Introdução
Os serviços que atendem pacientes com cefaleia precisam se adaptar a este momento pandêmico, minimizando consultas presenciais, mas mantendo os cuidados em saúde, orientando os pacientes a aderirem ao tratamento sugerido, e evitando gatilhos desencadeadores da migrânea.
Objetivo
Descrever o perfil clínico e epidemiológico de universitários com migrânea durante a pandemia COVID19.
Material e Métodos
Foi realizado um estudo descritivo de corte transversal entre acadêmicos de uma Universidade de Salvador, Bahia, no período de dezembro de 2020 a junho de 2021. Foram convocados por meio de aplicativo de mensagem instantânea WhatsApp® (WhatsApp Inc. Facebook Inc.) e direcionados via link para acesso ao Termo de Consentimento Livre e Esclarecido (TCLE), preenchidos via aplicativo de gerenciamento de pesquisa - Google Forms (Google LLC®, Califórnia, Estados Unidos). Esta pesquisa foi aprovada pelo Comitê̂ de Ética em Pesquisa 4.351.573.
Resultados
Dentre os 83 universitários entrevistados 85,5% apresentaram migrânea, 89,2% eram do sexo feminino, com média de idade de 25 anos (+/- 6,9), 81,9% solteiros e 41% de cor preta. Dentre os entrevistados, 13,3% apresentaram dificuldade em abrir a boca, 30,10% sentiam dor na região de têmporas ou próximo ao ouvido durante a mastigação, fonação ou deglutição; e 27,7% referiram ruídos ao mastigar falar ou bocejar, 55,4% cursaram com cervicalgia, 53% apresentaram rigidez no pescoço e 66,3% referiram dor irradiada para os braços. 15,5% apresentaram diagnóstico de COVID, 55,5% apresentaram cervicalgia. O consumo de medicamentos sintomáticos para migrânea passou de menos de uma vez ao mês (45,8%) para 1 a 4 vezes ao mês (60,2%).
Conclusões
O perfil clínico e epidemiológico de universitários com migrânea durante a pandemia COVID 19 foram mulheres jovens, solteiras, com sinais e sintomas de DTM e cervicalgia.
Influência das variantes genéticas +874T>A e -764G>C do Interferon-γ na suscetibilidade à migrânea
Authors: Bossa Beatriz Bagatim , Salomão Giovana Rodrigues , Lima Giovanna Sguissardi , Rocha Amanda Brant , Bello Valéria Aparecida , Frederico Regina Célia Poli , Silva Aline Vitali
Published: February 2022

IntroduçãoA migrânea é um distúrbio neurológico incapacitante e geneticamente determinado. Níveis elevados do interferon-γ(IFN-γ), citocina pró-inflamatória, contribuem para desencadear a dor.

ObjetivoAvaliar o efeito das variantes genéticas +874 T>A e -764 G>C do IFN-γ e seu efeito sobre a suscetibilidade e sintomasassociados à migrânea.

Material e métodosEstudo prospectivo do tipo caso-controle composto por 144 participantes entre 18 e 60 anos diagnosticados commigrânea e controles saudáveis. Projeto aprovado pelo Comitê de Ética em Pesquisa da PUCPR (n°3.029.972). Osparticipantes foram avaliados e responderam a entrevista estruturada sobre dados demográficos, antropométricos,clínicos, classificação e sintomas associados à migrânea. Também preencheram questionários validados referentesà incapacidade relacionada à migrânea (MIDAS), ansiedade (STAIY2) e depressão (IDB). A variantes genéticasdo IFN-γ foram analisadas por meio da reação em cadeia da polimerase com primers sequência alelo específica(PCR-SSP) ou PCR em tempo real. Foi realizada análise univariada seguida de regressão logística binária. Foi consideradadiferença estatística quando p<0,05.

ResultadosForam avaliados 144 indivíduos, sendo 68 com migrânea e 76 controles pareados para sexo, idade, etnia e índicede massa corporal. Pacientes com genótipo GC, da variante -764, apresentaram menor chance de migrânea quandocomparados com o genótipo GG (OR=0,15; p=0,047), maior produtor da citocina. Esse resultado corroboracom estudos clínicos que demonstraram aumento do IFN-γ em indivíduos com migrânea, especialmente na fase dedor5,6. Entretanto, a variante +874T>A não se associou à suscetibilidade à migrânea. Também não houve diferençaestatística entre os diferentes genótipos de ambas as variantes analisadas quanto ao tipo, presença ou ausência deaura, fotofobia, fonofobia, osmofobia, alodinia, depressão ou incapacidade da migrânea.

ConclusãoIndivíduos heterozigotos (GC) para variante -764 G/A do IFN-γ apresentaram chance 85% menor de apresentaremmigrânea quando comparados aos homozigotos GG.
Numeracy and Financial Wellbeing During the COVID-19 Pandemic
Authors: Wikoff Nora
Published: February 2022

This paper examines the role of numeracy in smoothing financial difficulties during the COVID-19 pandemic. The results show that numeracy was associated with a 30% reduction in late or non-payment of bills and a 20% reduction in the odds of feeling financially squeezed. The effect of numeracy on financial wellbeing was remarkably consistent across levels of education, ethnicity, and gender, suggesting that improving numeracy levels in the population may be an effective strategy to increase financial capability across the board. However, while numerate individuals were less likely to experience financial difficulty, high numeracy did not predict narrower gaps between Whites and ethnic minorities during the COVID-19 pandemic. Governments must take seriously the need to address the constraints and institutional barriers that keep individuals from achieving financial wellbeing.
Author’s Reflections on Making Sense of Numbers: Quantitative Reasoning for Social Research
Authors: Miller Jane
Published: February 2022

Miller, Jane E. 2021. Making Sense of Numbers: Quantitative Reasoning for Social Research. (Los Angeles: SAGE Publications) 608 pp. ISBN 978-1544355597.

This article introduces and provides an excerpt from Making Sense of Numbers: Quantitative Reasoning for Social Research, published by Sage. The book explains and illustrates how making sense of numbers involves integrating concepts and skills from mathematics, statistics, study design, and communications, along with information about the specific topic and context under study. It teaches how to avoid making common errors of logic, calculation, and interpretation by introducing a systematic approach and a healthy dose of skepticism to understanding and applying numbers to social research and everyday tasks.