bluuebunny/crossref_metadata_2025 huggingface dataset:
Resistance to Moisture-Induced Damage of Half-Warm-Mix Asphalt Concrete with Foamed Bitumen
Authors: Iwański Mateusz M. , Chomicz-Kowalska Anna , Maciejewski Krzysztof
Published: February 2020

Hot-mix asphalt (HMA) remains the predominant material for pavement surfacing. Mixing is performed at about 180 °C, depending on the bitumen used. Environmental concerns in terms of emissions and energy demand are fostering new sustainable technologies in road construction. Warm-mix asphalt (WMA) and half-warm-mix asphalt (HWMA) mixtures meet current expectations in that they are produced at lower temperatures, 100–130 °C, ensured by foaming the bitumen with water. The extent of temperature reduction requires that the mixture has adequate moisture and frost resistance, which is particularly important in countries that have a low-temperature climate. Asphalt concrete AC 8 S with 50/70-grade foamed bitumen modified with 0.6 wt.% surface-active agent (SAA) was used in the tests. To provide the AC mixture with the required resistance to climatic factors (water, temperature below 0), hydrated lime was added at 0, 15, 30, and 45 wt.% as limestone filler replacement. The influence of the hydrated lime addition on the air void content and resistance to moisture and frost damage was investigated according to the WT-2 2014 methodology based on EN 12697-12: 2008 and to the modified AASHTO T283 method. The optimum content of hydrated lime for filler replacement was determined through statistical analysis of the test results. With the optimum hydrated lime replacement of 30%, the required level of moisture and frost resistance of HWMA concrete with foamed bitumen is achieved. The results of this study confirmed the suitability of HWMA concrete with foamed bitumen for application in road construction practice.
Application of Electrochemical Atomic Force Microscopy (EC-AFM) in the Corrosion Study of Metallic Materials
Authors: Chen Hanbing , Qin Zhenbo , He Meifeng , Liu Yichun , Wu Zhong
Published: February 2020

Electrochemical atomic force microscopy (EC-AFM), a branch of a scanning probe microscopy (SPM), can image substrate topography with high resolution. Since its inception, it was extended to a wide range of research areas through continuous improvement. The presence of an electrolytic cell and a potentiostat makes it possible to observe the topographical changes of the sample surface in real time. EC-AFM is used in in situ corrosion research because the samples are not required to be electrically conductive. It is widely used in passive film properties, surface dissolution, early-stage corrosion initiation, inhibitor efficiency, and many other branches of corrosion science. This review provides the research progress of EC-AFM and summarizes the extensive applications and investigations using EC-AFM in corrosion science.
Preparation and Characterization of the Flame Retardant Decorated Plywood Based on the Intumescent Flame Retardant Adhesive
Authors: Wu Muting , Song Wei , Wu Yuzhang , Qu Wei
Published: February 2020

A novel type of flame-retardant decorated plywood (FDP) was designed and prepared based on one kind of intumescent flame-retardant adhesive. The flame-retardant adhesive was composed of the phosphorous-nitrogen flame retardant and melamine urea formaldehyde (MUF) resin. An adhesive was placed between the plywood substrate and the decorative veneer. The shear strength of the FDP satisfied the Class II (GB/T 9846) when the ratio of flame-retardant and MUF was less than 0.65. The thermal stability of the flame-retardant adhesive was measured by thermogravimetric analysis (TGA). The intumescent behaviors of adhesives were systematically investigated. The morphological and chemical structures of the intumescent char of the flame-retardant adhesive were characterized by the scanning electron microscopy (SEM) and Fourier transform infrared spectra (FTIR), respectively. The fire performance of FDP was assessed by the cone calorimeter and the single burning item test. The FDP exhibited the most effective barrier when the optimized ratio of ammonium polyphosphate (APP) and pentaerythritol (PER) in the adhesive is 3. The flame-retardant class of FDP could be up to class B1(B) according to GB/T 8624.
Experimental Study of Utilizing Recycled Fine Aggregate for the Preparation of High Ductility Cementitious Composites
Authors: Gao Dan Ying , Lv Mingyan , Yang Lin , Tang Jiyu , Chen Gang , Meng Yang
Published: February 2020

Waste concrete was recycled and crushed into fine aggregate to prepare a high ductility cementitious composite (HDCC) in this study, for helping dispose the massive amount of construction waste and for reserving natural resources. Firstly, the features of recycled fine aggregate (RFA) were analyzed in detail and compared with natural fine aggregate (NFA). After that, the mechanical properties, including compression, flexure, bending and tension, and the microstructure of high ductility cementitious composite (HDCC) prepared with RFA were systematically investigated and compared with that of HDCC prepared with NFA. The results show that, since RFA has a higher water absorption rate and contains 4.86 times as much crush dust as NFA, HDCC with RFA forms a denser matrix and a higher bond between fiber and matrix than HDCC with NFA. Thus, HDCC with RFA has higher compressive, flexural, bending and tensile strength. Meanwhile, the higher bond between the fiber and matrix of HDCC with RFA and the finer particle sizes of RFA can greatly promote the development of multiple cracking. As a result, HDCC with RFA exhibits more remarkable stain hardening, and presents 182.73% higher peak deflection in bending and 183.33% higher peak strain in tension than HDCC with NFA. Finally, with the consideration of fiber volume fraction, the prediction models for the peak strengths of HDCC with RFA were proposed. The prediction results show a good agreement with the test results.
The Root Nodule Microbiome of Cultivated and Wild Halophytic Legumes Showed Similar Diversity but Distinct Community Structure in Yellow River Delta Saline Soils
Authors: Zheng Yanfen , Liang Jing , Zhao Dong-Lin , Meng Chen , Xu Zong-Chang , Xie Zhi-Hong , Zhang Cheng-Sheng
Published: February 2020

Symbiotic associations between leguminous plants and their nodule microbiome play a key role in sustainable agriculture by facilitating the fixation of atmospheric nitrogen and enhancing plant stress resistance. This study aimed to decipher the root nodule microbiome of two halophytic legumes, Sesbania cannabina and Glycine soja, which grow in saline soils of the Yellow River Delta, China, using PacBio’s circular consensus sequencing for full-length bacterial 16S rRNA gene to obtain finer taxonomic information. The cultivated legume Glycine max was used for comparison. We identified 18 bacterial genera and 55 species in nodule samples, which mainly classified to Proteobacteria, and rhizobial genus Ensifer was the predominant group. The three legumes showed similarity in operational taxonomic unit (OTU) diversity but distinction in OTU richness, indicating that they harbor similar bacterial species with different relative contents. The results of principal coordinates analysis and ANOSIM tests indicated that G. soja and G. max have similar nodule bacterial communities, and these communities differ from that of S. cannabina. Wild legumes S. cannabina and G. soja both harbored a higher number of rhizobia, while G. max possessed more non-rhizobial bacteria. These differences could be associated with their adaptability to saline–alkali stress and revealed clues on the nodule endophytes with relative importance of culturable rhizobial symbionts.
Exploring the Scope of Macrocyclic “Shoe-last” Templates in the Mechanochemical Synthesis of RHO Topology Zeolitic Imidazolate Frameworks (ZIFs)
Authors: Brekalo Ivana , Deliz David E. , Kane Christopher M. , Friščić Tomislav , Holman K. Travis
Published: February 2020

The macrocyclic cavitand MeMeCH2 is used as a template for the mechanochemical synthesis of 0.2MeMeCH2@RHO-Zn16(Cl2Im)32 (0.2MeMeCH2@ZIF-71) and RHO-ZnBIm2 (ZIF-11) zeolitic imidazolate frameworks (ZIFs). It is shown that MeMeCH2 significantly accelerates the mechanochemical synthesis, providing high porosity products (BET surface areas of 1140 m2/g and 869 m2/g, respectively). Templation of RHO-topology ZIF frameworks constructed of linkers larger than benzimidazole (HBIm) was unsuccessful. It is also shown that cavitands other than MeMeCH2—namely MeHCH2, MeiBuCH2, HPhCH2, MePhCH2, BrPhCH2, BrC5CH2—can serve as effective templates for the synthesis of x(cavitand)@RHO-ZnIm2 products. The limitations on cavitand size and shape are explored in terms of their effectiveness as templates.
Competition between Intra and Intermolecular Triel Bonds. Complexes between Naphthalene Derivatives and Neutral or Anionic Lewis Bases
Authors: Zierkiewicz Wiktor , Michalczyk Mariusz , Scheiner Steve
Published: February 2020

: A TrF2 group (Tr = B, Al, Ga, In, Tl) is placed on one of the α positions of naphthalene, and its ability to engage in a triel bond (TrB) with a weak (NCH) and strong (NC−) nucleophile is assessed by ab initio calculations. As a competitor, an NH2 group is placed on the neighboring Cα, from which point it forms an intramolecular TrB with the TrF2 group. The latter internal TrB reduces the intensity of the π-hole on the Tr atom, decreasing its ability to engage in a second external TrB. The intermolecular TrB is weakened by a factor of about two for the smaller Tr atoms but is less severe for the larger Tl. The external TrB can be quite strong nonetheless; it varies from a minimum of 8 kcal/mol for the weak NCH base, up to as much as 70 kcal/mol for CN−. Likewise, the appearance of an external TrB to a strong base like CN− lessens the ability of the Tr to engage in an internal TrB, to the point where such an intramolecular TrB becomes questionable.
Nanoliposomes and Tocosomes as Multifunctional Nanocarriers for the Encapsulation of Nutraceutical and Dietary Molecules
Authors: Zarrabi Ali , Alipoor Amro Abadi Mandana , Khorasani Sepideh , Mohammadabadi M.-Reza , Jamshidi Aniseh , Torkaman Sarabanou , Taghavi Elham , Mozafari M.R. , Rasti Babak
Published: February 2020

Nanoscale lipid bilayers, or nanoliposomes, are generally spherical vesicles formed by the dispersion of phospholipid molecules in a water-based medium by energy input. The other nanoscale object discussed in this entry, i.e., tocosome, is a recently introduced bioactive carrier made mainly from tocopheryl phosphates. Due to their bi-compartmental structure, which consists of lipidic and aqueous compartments, these nanocarriers are capable of carrying hydrophilic and hydrophobic material separately or simultaneously. Nanoliposomes and tocosomes are able to provide protection and release of sensitive food-grade bioactive materials in a sustained manner. They are being utilized for the encapsulation of different types of bioactive materials (such as drugs, vaccines, antimicrobials, antioxidants, minerals and preservatives), for the enrichment and fortification of different food and nutraceutical formulations and manufacturing of functional products. However, a number of issues unique to the nutraceutical and food industry must first be resolved before these applications can completely become a reality. Considering the potentials and promises of these colloidal carrier systems, the present article reviews various aspects of nanoliposomes, in comparison with tocosomes, including the ingredients used in their manufacture, formation mechanisms and issues pertaining to their application in the formulation of health promoting dietary supplements and functional food products.
The Radiolabeling of a Gly-Sar Dipeptide Derivative with Flourine-18 and Its Use as a Potential Peptide Transporter PET Imaging Agent
Authors: Molotkov Andrei , W. Castrillon John , Santha Sreevidya , E. Harris Paul , K. Leung David , Mintz Akiva , Carberry Patrick
Published: February 2020

We have developed a novel fluorine-18 radiotracer, dipeptide 1, radiolabeled in two steps from mesylate 3. The initial radiolabeling is achieved in a short reaction time (10 min) and purified through solid-phase extraction (SPE) with modest radiochemical yields (rcy = 10 ± 2%, n = 5) in excellent radiochemical purity (rcp > 99%, n = 5). The de-protection of the tert-butyloxycarbonyl (Boc) and trityl group was achieved with mild heating under acidic conditions to provide 18F-tagged dipeptide 1. Preliminary analysis of 18F-dipeptide 1 was performed to confirm uptake by peptide transporters (PepTs) in human pancreatic carcinoma cell lines Panc1, BxPC3, and ASpc1, which are reported to express the peptide transporter 1 (PepT1). Furthermore, we confirmed in vivo uptake of 18F-dipeptide tracer 1 using microPET/CT in mice harboring subcutaneous flank Panc1, BxPC3, and Aspc1 tumors. In conclusion, we have established the radiolabeling of dipeptide 1 with fluoride-18, and demonstrated its potential as an imaging agent which may have clinical applications for the diagnosis of pancreatic carcinomas.
The Choice of Bread: The Association between Consumers’ Awareness of Dietary Fiber and Declared Intentions to Eat
Authors: Jezewska-Zychowicz Marzena , Królak Maria
Published: February 2020

The objective of the study was to find whether consumers declare an intention to eat bread enriched with fiber in the situation of availability of a plain bread and plain bread with grains, and how these intentions are related to their awareness of fiber in bread. The data were collected in a cross-sectional survey among 1014 Polish adults. Based on three pictures of rolls: plain wheat roll (CR), roll enriched with 12% fiber (RF), and roll topped with sunflower seeds (RSS), the participants’ perception regarding fiber content and its impact on intentions to eat were assessed. The respondents were not informed about the differences in composition of the rolls. Although RSS contained only slightly more fiber (0.98 g) than CR (0.81 g), and much less than RF (3.08 g), most of the respondents indicated RSS as containing the most fiber (50.8%) and declared their intention to eat it (39.0%). Respondents who pointed out the importance of fiber, and grains or wholemeal flour addition when making purchase decision, were more likely to declare an intention to eat RSS compared with CR. The low interest in fiber content in a diet increased the chances of declaring an intention to eat CR and RF. People less educated and with low incomes were more likely to declare an intention to eat CR rather than RSS. While people from rural areas were more likely to choose RSS compared with CR and RF. In conclusion, there is interest in bread enriched with fiber, but consumers experience difficulties in recognizing it. Declared intentions to eat each rolls were determined to the greatest extent by the perception of the roll as source of fiber. Thus, educational activities should be focused on consumers’ perception of fiber-rich products and their skills related to the selection of high-fiber foods.
Nutrition in Sepsis: A Bench-to-Bedside Review
Authors: De Waele Elisabeth , Malbrain Manu L.N.G. , Spapen Herbert
Published: February 2020

Nutrition therapy in sepsis is challenging and differs from the standard feeding approach in critically ill patients. The dysregulated host response caused by infection induces progressive physiologic alterations, which may limit metabolic capacity by impairing mitochondrial function. Hence, early artificial nutrition should be ramped-up and emphasis laid on the post-acute phase of critical illness. Caloric dosing is ideally guided by indirect calorimetry, and endogenous energy production should be considered. Proteins should initially be delivered at low volume and progressively increased to 1.3 g/kg/day following shock symptoms wane. Both the enteral and parenteral route can be (simultaneously) used to cover caloric and protein targets. Regarding pharmaconutrition, a low dose glutamine seems appropriate in patients receiving parenteral nutrition. Supplementing arginine or selenium is not recommended. High-dose vitamin C administration may offer substantial benefit, but actual evidence is too limited for advocating its routine use in sepsis. Omega-3 polyunsaturated fatty acids to modulate metabolic processes can be safely used, but non-inferiority to other intravenous lipid emulsions remains unproven in septic patients. Nutrition stewardship, defined as the whole of interventions to optimize nutritional approach and treatment, should be pursued in all septic patients but may be difficult to accomplish within a context of profoundly altered cellular metabolic processes and organ dysfunction caused by time-bound excessive inflammation and/or immune suppression. This review aims to provide an overview and practical recommendations of all aspects of nutritional therapy in the setting of sepsis.
The Association between Energy Balance-Related Behavior and Burn-Out in Adults: A Systematic Review
Authors: Verhavert Yanni , De Martelaer Kristine , Van Hoof Elke , Van Der Linden Eline , Zinzen Evert , Deliens Tom
Published: February 2020

Although it is believed that physical activity, sedentary, and dietary behavior (i.e., energy balance-related behavior) may decrease the risk of burn-out, the association between both is currently not well understood. Therefore, the aim of this systematic review was to synthesize studies investigating the relationship between energy balance-related behavior and burn-out risk. A systematic literature search was conducted in four databases, resulting in 25 included studies (ten experimental and 15 observational studies). Nine out of ten experimental studies showed that exercise programs were effective in reducing burn-out risk. Fourteen out of fifteen observational studies found a negative association between physical activity and burn-out risk, whereas one study did not find a relation. Two of the 15 observational studies also showed that being more sedentary was associated with a higher burn-out risk, and two other studies found that a healthier diet was related to a lower burn-out risk. No experimental studies were found for the latter two behaviors. It can be concluded that physical activity may be effective in reducing burn-out risk. The few observational studies linking sedentary and dietary behavior with burn-out risk suggest that being more sedentary and eating less healthy are each associated with higher burn-out risk. More high-quality research is needed to unravel the causal relationship between these two behaviors and burn-out risk.
A Focus Group Study about Oral Drug Administration Practices at Hospital Wards—Aspects to Consider in Drug Development of Age-Appropriate Formulations for Children
Authors: Rautamo Maria , Kvarnström Kirsi , Sivén Mia , Airaksinen Marja , Lahdenne Pekka , Sandler Niklas
Published: February 2020

Oral drug administration to pediatric patients is characterized by a lack of age-appropriate drug products and the off-label use of medicines. However, drug administration practices at hospital wards is a scarcely studied subject. The aim of this study was to explore the oral drug administration practices at pediatric hospital wards, with a focus on experiences and challenges faced, methods used to mitigate existing problems, drug manipulation habits, perceptions about oral dosage forms and future needs of oral dosage forms for children. This was a qualitative study consisting of focus group discussions with physicians, nurses and clinical pharmacists in a tertiary university hospital with the objective of bringing forward a holistic view on this research topic. These healthcare professionals recognized different administration challenges that were classified as either dosage form-related or patient-related ones. A lack of depot formulations developed especially for children as well as oral pediatric dosage forms of drug substances currently available as intravenous dosage forms was recognized. The preferred oral dosage forms were oral liquids and orodispersible tablets. Patient-centered drug administration practices including factors facilitating drug administration both at hospital wards and at home after patient discharge were identified. Among all healthcare professionals, the efficient cooperation in drug prescribing and administration as well as in educating the child’s caregivers in correct administration techniques before discharge and improving the overall discharge process of patients was emphasized. This study complements the prevalent understanding that new dosage forms for children of varying ages and stages of development are still needed. It also brings a holistic view on different aspects of oral drug administration to pediatric patients and overall patient-centered drug administration practices.
Synthesis and Characterization of pH-Responsive PEG-Poly(β-Amino Ester) Block Copolymer Micelles as Drug Carriers to Eliminate Cancer Stem Cells
Authors: Li Weinan , Sun Jialin , Zhang Xiaoyu , Jia Li , Qiao Mingxi , Zhao Xiuli , Hu Haiyang , Chen Dawei , Wang Yanhong
Published: February 2020

PEG-poly(β-amino ester) (PEG-PBAE), which is an effective pH-responsive copolymer, was mainly synthesized by Michael step polymerization. Thioridazine (Thz), which was reported to selectively eliminate cancer stem cells (CSCs), was loaded into PEG-PBAE micelles (PPM) prepared by self-assembly at low concentrations. The critical micelle concentrations (CMC) of PPM in water were 2.49 μg/mL. The pH-responsive PBAE segment was soluble due to protonated tertiary amine groups when the pH decreased below pH 6.8, but it was insoluble at pH 7.4. The Thz-loaded PEG-PBAE micelle (Thz/PPM) exhibited a spherical shape, and the drug loading was 15.5%. In vitro release of Thz/PPM showed that this pH-sensitivity triggered the rapid release of encapsulated Thz in a weakly acidic environment. The in vitro cytotoxicity and cellular uptake of various formulations at pH 7.4 and 5.5 were evaluated on the mammospheres (MS), which were sorted by MCF-7 human breast cancer cell lines and identified to be a CD44+/CD24− phenotype. The results of the cytotoxicity assay showed that blank micelles were nontoxic and Thz/PPM exhibited a similar anti-CSC effect on MS compared to Thz solution. Stronger fluorescence signal of Coumarin-6 (C6) was observed in MS treated by C6-loaded PPM (C6/PPM) at pH 5.5. The tumor inhibition rate and tumor weight of the free DOX and Thz/PPM groups were significantly different from those of the other groups, which free DOX and Thz/PPM effectively suppressed breast tumor growth in vivo. The above experimental results showed that Thz/PPM is an ideal and effective pH-responsive drug delivery carrier to a targeted therapy of CSCs.
Well-Defined Dual Light- and Thermo-Responsive Rod-Coil Block Copolymers Containing an Azobenzene, MEO2MA and OEGMA
Authors: Park Changjun , Heo Jaewon , Lee Jinhee , Kim Taehyoung , Kim Sang Youl
Published: February 2020

Here we report the dual light- and thermo-responsive behavior of well-defined rod-coil block copolymers composed of an azobenzene unit, 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) and oligo(ethylene glycol) methacrylate (OEGMA). Azobenzene-containing rigid rod blocks prepared by chain growth condensation polymerization of the azobenzene containing monomer were used as a macroinitiator of atom transfer radical polymerization (ATRP) after attaching an α-bromoisobutyryl group as an end group. Synthesis of well-defined rod-coil block copolymers with different coil block lengths was achieved by copolymerization of MEO2MA and OEGMA monomers. The synthesized polymers exhibited amphiphilic properties and polymeric micelles were formed in aqueous solution. The light-responsive behaviors of azobenzene moieties, photoisomerization by irradiation of light, and thermo-responsive behaviors of P(MEO2MA-co-OEGMA) coil blocks, aggregation by increment of temperature over lower critical solution temperature, were investigated. A dual stimuli-responsive behavior of the rod-coil block copolymers was observed when exposed to light and heat.
The Effect of Cross-Linking with Citric Acid on the Properties of Agar/Fish Gelatin Films
Authors: Uranga Jone , Nguyen Bach T. , Si Trung Trang , Guerrero Pedro , de la Caba Koro
Published: February 2020

The aim of this work was to assess the effect of fish gelatin–citric acid nucleophilic substitution and agar–citric acid esterification reactions on the properties of agar/fish gelatin films. Since temperature is an important cross-linking parameter, films were treated at 90 °C and 105 °C and film properties were compared to those of non-cured films. It was observed that temperature favored the aforementioned reactions, which induced physical and morphological changes. In this regard, darker films with a rougher surface were obtained for the films with a higher cross-linking degree. While mechanical properties were slightly modified, the barrier properties were enhanced due to the reactions that occurred. Therefore, these agar/fish gelatin films cross-linked through two different reactions can be considered to be promising materials as active films for different purposes, such as active packaging or pharmaceutical applications.
Synthesis, Characterization, Self-Assembly, and Irritation Studies of Polyglyceryl-10 Caprylates
Authors: Zhang Guangyan , Bao Chenhui , Fu Kaiqiao , Lin Yaolin , Li Tianlong , Yang Huping
Published: February 2020

1,4-dioxane should be less than or equal to 10 ppm in finished cosmetic products according to the recommendation of the Scientific Committee on Consumer Safety, but it is often generated as a by-product during the manufacturing process of poly(ethylene glycol) (PEG)-based derivatives. In order to avoid the possible risk caused by 1,4-dioxane, it might be a good choice for preparing cosmetic ingredients by using polyglycerin (PG) instead of PEG as a hydrophilic segment. In the present study, polyglyceryl-10 caprylates were synthesized by the esterification reaction between polyglycerin-10 and caprylic acid. FTIR and 1H NMR were utilized to confirm the chemical structures of the obtained polyglyceryl-10 caprylates. Light transmittance was availed to investigate the water solubility of polyglyceryl-10 caprylates. The self-assembly behavior, size, and size distribution of polyglyceryl-10 caprylates were investigated by dynamic light scattering. The makeup cleansing effect was also evaluated by in vitro and in vivo methods. Irritation was evaluated by hen’s egg test-chorioallantoic membrane assay (HET-CAM). Results showed that polyglyceryl-10 monocaprylate could self-assemble into nanoparticles in the water at the concentration range of 2.5–10 wt% with a transparent appearance. The diameter of formed nanoparticles was around 100 nm with a narrow particle size distribution around 0.1 at the concentration of 2.5 wt% or 5 wt%. Polyglyceryl-10 monocaprylate exhibited good removal effect against makeup and excellent removal efficacy against pen eyeliner. The irritation of polyglyceryl-10 monocaprylate evaluated by HET-CAM at the concentration of 4 wt% was moderate irritant (irritation score = 8.4), which was lower than that of PEG-6 caprylic/capric glycerides (severe irritant, irritation score = 14.1). Therefore, polyglyceryl-10 monocaprylate might be a promising cosmetic ingredient for transparent makeup removing water.
Stable Symmetric Matrix Form Framework for the Elastic Wave Equation Combined with Perfectly Matched Layer and Discretized in the Curve Domain
Authors: Sun Cheng , Yang Zailin , Jiang Guanxixi
Published: February 2020

In this paper, we present a stable and accurate high-order methodology for the symmetric matrix form (SMF) of the elastic wave equation. We use an accurate high-order upwind finite difference method to define spatial discretization. Then, an efficient complex frequency-shifted (CFS) unsplit multi-axis perfectly matched layer (MPML) is implemented using the auxiliary differential equation (ADE) that is used to build higher-order time schemes for elastodynamics in the unbounded curve domain. It is derived to be compatible with SMF. The SMF framework has a general form of a hyperbolic partial differential equation (PDE) that can be expanded to different dimensions (2D, 3D) or different wave modal (SH, P-SV) without requiring significant modifications owing to a simplified process of derivation and programming. Subsequently, an energy analysis on the framework combined with initial boundary value problems is conducted, and the stability analysis can be extended to a semi-discrete approximation similarly. Thus, we propose a semi-discrete approximation based on ADE CFS-MPML in which the curve domain is discretized using the upwind summation-by-parts (SBP) operators, and where the boundary conditions are enforced weakly using the simultaneous approximation terms (SAT). The proposed method’s robustness and adequacy are illustrated by conducting several numerical simulations.
Single-Valued Neutrosophic Linguistic-Induced Aggregation Distance Measures and Their Application in Investment Multiple Attribute Group Decision Making
Authors: Yu Guansheng , Zeng Shouzhen , Zhang Chonghui
Published: February 2020

This paper studied the single-valued neutrosophic linguistic distance measures based on the induced aggregation method. Firstly, we proposed a single-valued neutrosophic linguistic-induced ordered weighted averaging distance (SVNLIOWAD) measure, which is a new extension of the existing distance measures based on the induced aggregation view. Then, based on the proposed SVNLIOWAD, a novel induced distance for single-valued neutrosophic linguistic sets, namely the single-valued neutrosophic linguistic weighted induced ordered weighted averaging distance (SVNLWIOWAD), was developed to eliminate the defects of the existing methods. The relationship between the two proposed distance measures was also explored. A multiple attribute group decision making (MAGDM) model was further presented based on the proposed SVNLWIOWAD measure. Finally, a numerical example concerning an investment selection problem was provided to demonstrate the usefulness of the proposed method under a single-valued neutrosophic linguistic environment and, then, a comparison analysis was carried out to verify the flexibility and effectiveness of the proposed work.
A New Filter Nonmonotone Adaptive Trust Region Method for Unconstrained Optimization
Authors: Wang Xinyi , Ding Xianfeng , Qu Quan
Published: February 2020

In this paper, a new filter nonmonotone adaptive trust region with fixed step length for unconstrained optimization is proposed. The trust region radius adopts a new adaptive strategy to overcome additional computational costs at each iteration. A new nonmonotone trust region ratio is introduced. When a trial step is not successful, a multidimensional filter is employed to increase the possibility of the trial step being accepted. If the trial step is still not accepted by the filter set, it is possible to find a new iteration point along the trial step and the step length is computed by a fixed formula. The positive definite symmetric matrix of the approximate Hessian matrix is updated using the MBFGS method. The global convergence and superlinear convergence of the proposed algorithm is proven by some classical assumptions. The efficiency of the algorithm is tested by numerical results.
Binomial Regression Models with a Flexible Generalized Logit Link Function
Authors: Prasetyo Rindang Bangun , Kuswanto Heri , Iriawan Nur , Ulama Brodjol Sutijo Suprih
Published: February 2020

In binomial regression, a link function is used to join the linear predictor variables and the expectation of the response variable. This paper proposes a flexible link function from a new class of generalized logistic distribution, namely a flexible generalized logit (glogit) link. This approach considers both symmetric and asymmetric models, including the cases of lighter and heavier tails, as compared to standard logistic. The glogit is created from the inverse cumulative distribution function of the exponentiated-exponential logistic (EEL) distribution. Using a Bayesian framework, we conduct a simulation study to investigate the model performance compared to the most commonly used link functions, e.g., logit, probit, and complementary log–log. Furthermore, we compared the proposed model with several other asymmetric models using two previously published datasets. The results show that the proposed model outperforms the existing ones and provides flexibility fitting the experimental dataset. Another attractive aspect of the model are analytically tractable and can be easily implemented under a Bayesian approach.
A Feasible Community Detection Algorithm for Multilayer Networks
Authors: Chen Dongming , Du Panpan , Jiang Qianrong , Huang Xinyu , Wang Dongqi
Published: February 2020

As a more complicated network model, multilayer networks provide a better perspective for describing the multiple interactions among social networks in real life. Different from conventional community detection algorithms, the algorithms for multilayer networks can identify the underlying structures that contain various intralayer and interlayer relationships, which is of significance and remains a challenge. In this paper, aiming at the instability of the label propagation algorithm (LPA), an improved label propagation algorithm based on the SH-index (SH-LPA) is proposed. By analyzing the characteristics and deficiencies of the H-index, the SH-index is presented as an index to evaluate the importance of nodes, and the stability of the SH-LPA algorithm is verified by a series of experiments. Afterward, considering the deficiency of the existing multilayer network aggregation model, we propose an improved multilayer network aggregation model that merges two networks into a weighted single-layer network. Finally, considering the influence of the SH-index and the weight of the edge of the weighted network, a community detection algorithm (MSH-LPA) suitable for multilayer networks is exhibited in terms of the SH-LPA algorithm, and the superiority of the mentioned algorithm is verified by experimental analysis.
Diversity and Host Interactions among Virulent and Temperate Baltic Sea Flavobacterium Phages
Authors: Nilsson Emelie , Bayfield Oliver W. , Lundin Daniel , Antson Alfred A. , Holmfeldt Karin
Published: February 2020

Viruses in aquatic environments play a key role in microbial population dynamics and nutrient cycling. In particular, bacteria of the phylum Bacteriodetes are known to participate in recycling algal blooms. Studies of phage–host interactions involving this phylum are hence important to understand the processes shaping bacterial and viral communities in the ocean as well as nutrient cycling. In this study, we isolated and sequenced three strains of flavobacteria—LMO6, LMO9, LMO8—and 38 virulent phages infecting them. These phages represent 15 species, occupying three novel genera. Additionally, one temperate phage was induced from LMO6 and was found to be competent at infecting LMO9. Functions could be predicted for a limited number of phage genes, mainly representing roles in DNA replication and virus particle formation. No metabolic genes were detected. While the phages isolated on LMO8 could infect all three bacterial strains, the LMO6 and LMO9 phages could not infect LMO8. Of the phages isolated on LMO9, several showed a host-derived reduced efficiency of plating on LMO6, potentially due to differences in DNA methyltransferase genes. Overall, these phage–host systems contribute novel genetic information to our sequence databases and present valuable tools for the study of both virulent and temperate phages.
Modelling the Impact of Leaky Barriers with a 1D Godunov-Type Scheme for the Shallow Water Equations
Authors: Leakey Shannon , Hewett Caspar J. M. , Glenis Vassilis , Quinn Paul F.
Published: February 2020

There is increasing interest in distributing small-scale interventions across the landscape as an alternative means of reducing flood risk. One such intervention, the leaky barrier, is introduced in channels to slow down high flows and encourage temporary storage on the floodplain. While these barriers have been implemented widely, there is still resistance to their use at the scales required to impact significantly on flood risk, at least partially due to an evidence gap. In particular, there is no standard method for representing leaky barriers in hydraulic models. This study sets out a methodology for developing mathematical models which capture the hydraulics of leaky barriers accurately, allowing key questions about their combined behaviour in catchments to be answered. A 1D Godunov-type scheme is set up and leaky barriers incorporated with internal boundary conditions. This model is tested against benchmarks from the literature and new steady-state data, and then run predictively on transient cases. The method will help to answer key questions about the optimal leakiness of small-scale interventions, the limits to their usefulness, and how combinations of barriers may or may not cause synchronisation problems when the effect of multiple barriers is aggregated.
Experimental Study on Hydraulic Characteristics of Pneumatic Lifting Pump
Authors: Zuo Juanli , Li Fengchao , Zhang Ning , He Denghui , Wang Wen , Zhang Jie
Published: February 2020

A pneumatic lifting pump is used in sewage treatment, offshore oil production, and other fields because of its simple structure and strong practicability. In order to study its internal hydraulic characteristics and gas-liquid two-phase flow, this paper carries out experimental research on the influence of different air intake modes and riser diameters on the performance of a pneumatic lifting pump. The air-water two-phase flow pattern in the riser and motion characteristics of bubble formation at the nozzle are obtained by a high-speed camera. Through theoretical analysis, the theoretical model of a pneumatic lifting pump is established, and experimental results verify the theoretical model well. The results show that when the submergence ratio is constant, the lifting efficiency decreases with the smaller intake area under different intake areas; and the influences of different holes distributions on liquid flow rate and lifting efficiency are not significant under the same intake area. At the same submergence ratio, the smaller the riser diameter, the smaller the final lifting liquid flow rate and the larger the lifting efficiency peak value.
An Experimental Study on the Effects of Atomized Rain of a High Velocity Waterjet to Downstream Area in Low Ambient Pressure Environment
Authors: Liu Dan , Lian Jijian , Liu Fang , Liu Dongming , Ma Bin , Shi Jizhong
Published: February 2020

A better understanding of the atomized rain characteristics in low ambient pressure areas is beneficial in reducing the jeopardizing effect of flood discharge atomization on high-altitude hydropower stations. A random splash experiment is designed with two measurement planes to investigate the effects of low ambient pressure on downstream atomized rain under the complicated conditions of low ambient pressure (within 0.60P0~1.00P0) and high waterjet velocity (at a magnitude of 10 m/s). The results demonstrate that the atomized rain (rain intensity ≥ 2 mm/h) downstream, characterized by two-dimensional distribution, can be enhanced by decreasing the ambient pressure and by increasing the inflow discharge. When the ambient pressure decreases at the same inflow discharge, both the distance of the rain intensity lines (40 mm/h, 10 mm/h, 2 mm/h) in the horizontal plane from the constricted nozzle outlet and the average rain amount in the inclined plane within the atomized source ratio of ((0~30) × 10−3)% appear as “linear” growth. With the ambient pressure decreasing by 0.10P0, the range of those characteristic rain intensity lines is expanded by 0.68%~1.37%, and the average rain amount is enlarged by 11.06%~20.48%. When keeping the low ambient pressure unchanged, both the point average rain intensity reduction along the releasing centerline and the surface average rain amount growth with increased inflow discharge all follow an exponential function. The aeration reduction in the waterjet boundary and the resistance reduction in atomized water-droplets are contributing factors for the enhancement effect of low ambient pressure. This study can enable the establishment of a foundation to further predict flood discharge atomization in a high-altitude environment.
Geometry-Based Assessment of Levee Stability and Overtopping Using Airborne LiDAR Altimetry: A Case Study in the Pearl River Delta, Southern China
Authors: Wang Xianwei , Wang Lingzhi , Zhang Tianqiao
Published: February 2020

Levees are normally the last barrier for defending flood water and storm surges in low-lying coastal cities. Levees in a large delta plain were usually constructed in different time and criteria and have been changing with age as well. Fast and quantitative assessment of levee stability is critical but faces many challenges. This study designs a scoring approach to quickly assess levee stability and overtopping threats with geometric parameters from airborne Light Detection and Ranging (LiDAR). An automated procedure is developed to extract levees geometric parameters from 0.5 m grid LiDAR elevation, such as crown height, width and landside slope. The surveyed levee is seated in the Hengmen waterway in the Pearl River Delta, Southern China. Results show that the stability index using the assessment scores is higher than and superior to the common qualified rates adopted in previous studies. The qualified rate is defined as the count percentage that each parameter meets the designed criteria, while the assessment score proposed in this study assigns different credits to those below/above the designed criteria. The continuous crown heights provide detailed information on levee overtopping threats. The crown heights of levee A and B are above the designed elevation and the flood stage (4.5 m) in a 200-year return period. The crown heights of levee C, D and E are generally lower than 4.5 m and vary in a large range on different sections. The middle section of levee E for the harbor and dock area has front elevation slightly below the flood stage (3.54 m) in a 20-year return period. Moreover, the high precision LiDAR altimetry data reveal various morphological modifications in all levees, such as natural subsidence and artificial modifications, which greatly reduce levees safety and are severe threats to the community. The procedures and assessment approach developed in this study can be easily applied for levees fast assessment in the entire Pearl River Delta and somewhere else, thus offer a suitable mitigation suggestion ahead of levee failure or overtopping.
Investigation of enrofloxacin and ciprofloxacin residues by LC-MS/MS in chicken liver marketed in Afyonkarahisar
Authors: ARSLAN ACARÖZ Damla , BAYSU SÖZBİLİR Nalan
Published: February 2020

Antibiotic residues can remain in animal source foods, mainly in the liver. Enrofloxacin (ENR) is a synthetic fluoroquinolone antimicrobial agent which is extensively used to treat bacterial infections in poultry. This study aimed to evaluate ENR and its main metabolite ciprofloxacin (CIP) occurrence in 100 chicken livers marketed Afyonkarahisar, Turkey. Chicken liver samples were analyzed by LC-MS/MS method with limits of detection for 1.17 μg/kg (ENR) and 1.24 μg/kg (CIP). ENR and CIP were detected in 39% and in 31% of samples, respectively. However, the total sum of both antibiotic residue levels was found to be far below the established maximum residue level (200 μg/kg) in all of chicken liver samples. In conclusion, according to the results of this study, chicken livers marketed in Afyonkarahisar city are safe for public health regarding ENR and CIP residues. Nonetheless, periodical control of chicken liver is advised due to the high incidence of these antibiotics.
Pelatihan Kerajinan Eceng Gondok di Kecamatan Banyubiru untuk Menumbuhkan Wirausaha Baru
Authors: Setiati Ning , Retnoningsih Amin , Dewi Nur Kusuma
Published: February 2020

The aim of community service carried out by KKN students in Kebondowo Village and Demakan Village, Banyubiru District, located around Rawapening, is 1) to provide easy use of water hyacinth; 2) provide practical skills in the use of social media for marketing; 3) reduce the skill level of the skill briefing. The methods used in completing the objectives are 1) training in material assistance, 2) practical assistance to finishing, 3) business analysis and marketing. The results of these mentoring activities are: 1) increased workforce capable of making handicrafts from water hyacinth in a number of forms; 2) product marketing at the Rawa Pening lake attraction, Bukit Cinta and provincial level bazaar and expo events; also 3) helps businesses make social media also join in and fill content with product images. Overall, the outputs from this service were obtained and strived to be owned, strived to be independent, production, and consultation with UNNES.
Peningkatan Pembelajaran Melalui Situs Media Online dengan Metode Blended Learning Pada Masyarakat Desa Bojongcae
Authors: Juliannisa Indri Arrafi
Published: February 2020

This community service activity is intended to provide more knowledge to the residents of Bojongcae- Lebak Regency, especially for parents, and children and teenagers who relied on manual and limited teaching material for education with increasing the ability of partner groups in the world of education. The partner groups in this study are housewives who are members of the PKK group, and teenagers who have the ability to speak English better than housewives and other teenagers.The material provided in this community service program is internet based using social media instragram with the account name "ayokita.belajar". The material chosen by the service team are learning of English language and learning of skills related to daily needs, the selection of material and social media was agreed by the partner group, with this activity the partner group is expected to be able to provide teaching materials more creative, innovative and easily understood. Moreover, addition of knowledge about study by e-learning is expected that the process of providing subject matter can be more modern and follow more sophisticated technological developments. The result of this community service activity is that partner groups can create a training or learning activity with English-language material and training videos to improve their daily skills. Measurement of learning with social media have done by way of children and adolescents given questions about material that has been uploaded on social media Instagram