bluuebunny/crossref_metadata_2025 huggingface dataset:
Abnormal anti-Müllerian hormone level may be a trigger for breast cancer in young women: A case-control study
Authors: Jalaeefar Amirmohsen , Moini Ashraf , Eslami Bita , Alipour Sadaf , Shirkhoda Mohammad , Aryan Arvin , Mahmoodzadeh Habibollah , Omranipour Ramesh
Published: February 2021

Background: Anti-Müllerian hormone (AMH) is a known sensitive biomarker for fertility and ovarian reserve. The results of in vivo and human studies showed inconsistency with respect to the relation between AMH and breast cancer.
Objective: To compare the AMH level of young Iranian women with early breast cancer who have not received any treatment compared to that of healthy women.
Materials and Methods: In this case-control study, 58 breast cancer cases were recruited from the breast oncology clinic of two university hospitals. They were diagnosed with an in situ or invasive breast cancer before any anticancer treatment between August 2018 and April 2019. Healthy controls (n = 58) were selected from women referred to a gynecologic outpatient clinic without any symptoms of cancer or infertility. AMH was measured by the AMH enzyme-linked immunosorbent assay kits in one laboratory.
Results: Final analysis showed that the AMH means of case and control were not statistically significant (3.36 ± 2.95 vs 3.13 ± 1.79). However, the lower and higher AMH level categories are more prevalent in breast cancer compared to the control. Pearson’s correlation test showed that the AMH level was negatively correlated with age (r = -0.44, p< 0.001). The results of logistic regression analysis considering confounding factors showed the positive association between breast cancer and lower (Odds Ratio [OR] = 5.98, p = 0.02) and higher quartile of AMH level (OR = 4.95, p = 0.01).
Conclusion: Our results suggest that abnormal AMH level is more frequent in young breast cancer patients. Further investigation considering AMH determinants is required.
Key words: Anti-Müllerian hormone, Breast cancer, Biomarkers, Ovarian reserve.
Human Values In Maqamat Badiuzzaman Al-Hamdani
Authors: Fitriani Laily
Published: February 2021

Abbasiyah time was a golden period in the era of glory in all fields of science. This time was marked by the development of religious and non-religious sciences, as well as literature. Maqamat art was one type of Abbasiyah prose that experienced rapid development, with Badiuzzaman al-Hamdani as a figure whose maqamat work consist of human values. Maqamat is a short story that contains the events of the main characters narrated by certain narrators. The language style is mostly in the form of 'and badi' and ends with advice.This study purposes to describe the characteristics in Badiuzzaman al-Hamdani’s Maqamat and explain human values in Badiuzzaman al-Hamdani’s Maqamat. Data collection is conducted with documentations and heuristic techniques and analyzed qualitatively. The results of the study explain: 1) Five characteristics in Badiuzzaman al-Hamdani’s Maqamat consist of themes, characterizations, plot, background and point of view, and 2) Moral values portrayed in Badiuzzaman al-Hamdani’s Maqamat are human values and justice values. Keywords: Badiuzzaman al-Hamdani’s Maqamat, characteristics, content analysis, moral values
Al-Uslūb al-Taqābulī fī Sūrah al-Baqarah wa Dilālatuhu
Authors: Oktaviana Anisa Rosi
Published: February 2021

The purpose of this study is to explain and identify the conflicting meanings in Arabic. It refers to the Muqabalah Theory in Balaghah, and At-Tadzat in Semantics using Ali Al-Khouli’s opinion, there are also different patterns of sentence contradiction, which justifies the importance of this study. The data were obtained from AL-Qur'an Surah Al-Baqarah. This research employs a descriptive qualitative method. In Balaghah At-Taqabuly or Al-Muqabalah is a sequence of contradictory meanings; while in the Semantics, it is called At-Tadzat which literally means Antonym. In line with the At-Taqabuly or Al-Muqabalah, it has no special division. But in semantics, there is a difference between the old meaning and the new meaning. In the old meaning, At-Tadzat is interpreted as a different word but has the same meaning, and conversely Ali Al-Khouli interpreted At-Tadzat as 2 opposing words which are the understanding of At-Tadzat in a new meaning. At -Tadzat is divided into 9 parts: 1) Al-Had, 2) Al-'Aks, 3) Al-Mutadarrij, 4) Al-Imtidadi, 5) Al-'Amudy, 6) Al-Juz'i, 7) Al -Dairi, 8) Al-Rutbi, 9) Al-Intisab. In this study only found 5 types of At-Tadzat namely Al-Had, 2) Al-'Aks, 3) Al-Mutadarrij, 4) Al-Imtidadi, 5) Al-'Amudy. The study found 10 syntactic patterns of meaning opposition of the Surah of Al-Baqarah, Ism Maushul, Idhofah, Jar Majrur, Anwa 'Al -otal, Maf'ul bih, Ism Inna, Na't wa Man'ut, At-Tamyiiz, Al-Hal, and Muabtada wa Khabar
ATEÍSMO MODERNO
Authors: Xavier Erico Tadeu , Cardoso Marcelo Ferreira
Published: February 2021

O ateísmo tem crescido nas últimas décadas pela militância de filósofos e estudiosos da ciência que apregoam um novo ateísmo. O objetivo deste estudo é refletir sobre a nova fase do ateísmo na sociedade atual e seus principais divulgadores buscando reconhecer a expansão desse fenômeno e sua influência no contexto religioso. Por meio da pesquisa bibliográfica, observa-se que o neoateísmo se apresenta com as mesmas ideias do ateísmo, mas com uma nova visão dos conceitos e pensamentos, tornando mais acessível a divulgação do movimento ateísta. Os representantes do neoateísmo combatem a ideia de Deus ou deuses e a crença no sobrenatural, atacando especialmente o fundamentalismo religioso e a influência religiosa na política e na sociedade, enfatizando a evidência científica em detrimento da fé na divindade. O ateísmo tem se propagado com maior facilidade hoje em dia, sobretudo por buscar respostas aos questionamentos humanos na razão e na ciência, mas atraindo também outras pessoas pelo uso de novos argumentos que aceitam no movimento ateísta, a fé e a espiritualidade. Conclui-se que os neoateístas têm propagado a mensagem ateísta sob nova roupagem com o intuito de atrair mais pessoas ao movimento, promovendo o afastamento da religião e da crença em Deus em prol do materialismo e consequente secularismo.
Developing public service knowledge and learning about complex systems: using a community of practice to integrate theory and practice
Authors: Haynes Philip , Darking Mary , Stroud Julia
Published: February 2021

A Community of Practice Knowledge Exchange (CPKE) comprising of practitioners and academics with an interest in complexity theory was formed. The central activity of the CPKE was an agreement that each would develop a case study that integrated complexity theory and challenges in practice. In the first phase, members agreed definitions of core concepts and used them to describe the systems they were working in.  Frequent contact was via a virtual learning environment.  This activity was supplemented with face-to-face contact, in the form of half-day workshops. After several months, the CPKE agreed two core pieces of reading to provide a theoretical basis. These were popular because of their applied focus. The CPKE evolved to a second phase.  Diverse case studies of practice-based challenges were used to share experiences of complex systems. A key event was the presentation of case studies as complex systems using a shared conceptual language generated by earlier learning. In the final phase, the CPKE considered interventions into the case studies and created and applied a management toolkit to develop approaches to possible management interventions. Through the development of the toolkit, the CPKE became interested in the role of values in a complexity-based practice and how coherent and shared values could aid more informed interventions. The use of complexity theory changed the ontology of management practice by facilitating an understanding and acceptance of uncertainty and that optimal approaches often required a relational and cooperative approach built on shared values, rather than an instrumental and singular management orthodoxy.
The “Resource Curse”: Lessons of the Third World
Authors: Shmat V.
Published: February 2021

According to the hypothesis known as the “resource curse”, natural resources abundance is a brake on economic growth of many Third World countries. But is it really so? The author believes there are deeper reasons why the Third World in general – regardless of the amount of raw material resources available in each country – cannot achieve the same level of welfare as the First World. The “resource curse” theory looks for the origins of the resourceful countries’ economic problems in the institutional sphere. But this seems misleading because of excessively narrow “here and now” approach. The economic and socio-political institutions of individual countries are regarded in short periods of time when “curse” declared itself. Its typical manifestations, such as rent-seeking, stagnation or degradation of the institutions, authoritarian power, snowballing public debt and symptoms of Dutch disease, were seen in many Third World countries long before the development of the major sources of raw materials and regardless of the availability or absence of them. Therefore, it seems appropriate to speak of a kind of “three-fold institutional curse” as an explanation of continuing underdevelopment of many countries and territories. Poor national institutions in the Third World countries are not actually caused by the presence or absence of concentrated natural resources. This is the result of prior historical development with series of discrete transitions from one condition to another: from colonial status – to independent statehood; from poverty – to unexpected wealth mostly based on the exploitation of the natural resources. Qualitative transformation of national institutions usually lags far behind. As a consequence, institutional development enters into a state of stagnation (inhibiting or destabilizing economic growth) that can stretch for very long periods of time. The author concludes that the presence or absence of resources, in fact, has no fundamental impact on the nature of socio-economic development of Third World countries. The major reason hindering institutional progress has external nature, that is heavy economic dependence on the First World (coupled with informal political subordination). This circumstance begets the “resource nationalism” by the developing countries – exporters of raw materials and fuel. History of “resource nationalism” provides a useful lesson for Russia whose economy is features by growing dependency on resources. Acknowledgement. The article has been supported by a grant of the Russian Science Foundation. Project № 14-18-02345.
POSSIBILIDADE DE RECUPERAÇÃO JUDICIAL DO PRODUTOR RURAL
Authors: Ronquim Filho Adhemar , Oranges Cezarino Luciana
Published: February 2021

O presente estudo focará na análise da possibilidade de recuperação judicial do produtor rural, com base na LEFRJ. Verificar-se-á se esta figura tem de seguir os requisitos gerais para o deferimento de RJ ou se a este existem diferenças para aquele. O foco será na análise doutrinária, legal e especialmente jurisprudencial, a qual, em movimento, hoje vem fixando dois requisitos, os quais seriam: a comprovação do exercício da atividade de mais de 2 (dois) anos e a regularidade, a qual se manifesta pela inscrição no Registro no Comercial com antecedência ao requerimento do processo recuperatório.
COLABORAÇÃO PREMIADA: A (IN)COMPATIBILIDADE ENTRE A CONFISSÃO E O PRINCÍPIO FUNDAMENTAL DA NÃO AUTOINCRIMINAÇÃO
Authors: Felipe Silva Aliane , Cota Maria do Carmo
Published: February 2021

A colaboração premiada é um mecanismo de cunho investigatório, cuja utilização é cada vez mais crescente no processo penal brasileiro, e os assuntos que circunscrevem o presente tema apresentam muitas divergências doutrinárias. Nesse cenário, o interrogatório do acusado implica em possível produção de elementos incriminatórios em relação a terceiros e a ele próprio. Desse modo, no ato de colaborar, esvazia-se ou renuncia-se o direito fundamental da não autoincriminação, sendo que as cláusulas do acordo não podem servir como renúncia, prévia e definitiva, ao pleno exercício de direitos de ordem fundamental. Assim sendo, este trabalho é fruto de uma abordagem qualitativa e utiliza a discussão teórica-bibliográfica, a partir da investigação científica baseada em revisão de literatura específica e em consulta à legislação brasileira. Ademais, tem como objetivo apresentar como acontece a interação entre a delação premiada, a confissão e o direito constitucionalmente previsto a não autoincriminação do colaborador. Ver-se-á que mitigar o direito fundamental ao silêncio não configura qualquer inconstitucionalidade, pois tal garantia pode ser passível de renúncia pelo colaborador, desde que haja respeito à voluntariedade do ato.
LABSOCIAL - DROGAS:UMA EXPERIÊNCIA DIALÓGICA POR MEIO DA EXTENSÃO CURRICULAR NO CURSO DE DIREITO DA UFT
Authors: Alves da Costa Neto Gabriel , Ferreira Amaral Gustavo , Morais Lemos Matheus , Rodrigues Barros Milena Gabriela , Reis Ferreira Patrício , Almeida Cristiane Roque de
Published: February 2021

RESUMO: Por meio deste trabalho, relatamos a experiência de criação coletiva do projeto de extensão LabSocial – Drogas: experiências dialógicas entre a universidade e a sociedade, no contexto do programa de extensão Centro Regional de Referência sobre Drogas – CRR/UFT/CENTRO-SUL, do Curso de Direito da Universidade Federal do Tocantins – UFT. Destacamos os resultados das primeiras ações do projeto, realizadas durante o ano de 2019 na Escola Estadual Elizângela Glória Cardoso, em Palmas-TO, com adolescentes e jovens do Ensino Médio. A atividade extensionista demonstrou que o laboratório de ideias, na perspectiva do trabalho horizontal e interdisciplinar, é uma estratégia valiosa à abordagem do tema, devendo ser considerada no trabalho com jovens no ambiente escolar, bem como em outros espaços formativos.

PALAVRAS-CHAVE: Diálogo horizontal. Drogas e juventudes. Laboratório de ideias. Prevenção ao uso indevido de drogas.
Vegetation Structure Index (VSI): Retrieving Vegetation Structural Information from Multi-angular Satellite Remote Sensing
Authors: Sharma Ram C.
Published: February 2021

Utilization of Bidirectional Reflectance Distribution Function (BRDF) model parameters obtained from the multi-angular remote sensing is one of the approaches for the retrieval of vegetation structural information. In this research, the potential of multi-angular vegetation indices, formulated by the combination of multi-spectral reflectance from different view angles, for the retrieval of forest above ground biomass was assessed. This research was implemented in the New England region with the availability of a high quality forest inventory database. The multi-angular vegetation indices were generated by the simulation of the Moderate Resolution Imaging Spectroradiometer (MODIS) BRDF/Albedo Model Parameters Product (MCD43A1 Version 6) based BRDF parameters. The effects of seasonal (spring, summer, autumn, and winter) composites of the multi-angular vegetation indices on above ground biomass, angular relationship of the spectral reflectance with above ground biomass, and the interrelationships between the multi-angular vegetation indices were analyzed. Among the existing multi-angular vegetation indices, only the Nadir BRDF-adjusted NDVI ( and Hot-spot incorporated NDVI ( showed significant relationship (more than 50%) with the above ground biomass. This research proposed two more sensitive vegetation structural indices, Fore-scattering Back-scattering NDVI and Vegetation Structure Index (VSI). The Fore-scattering Back-scattering NDVI showed higher sensitivity (R2 = 0.62, RMSE = 52.46) towards the above ground biomass than existing multi-angular vegetation indices. Furthermore, the VSI performed in the most efficient way explaining 64% variation of the above ground biomass, suggesting that the right choice of the spectral channel and observation geometry should be considered for improving the estimates of the above ground biomass. In addition, the right choice of seasonal data (summer) was found to be important for estimating the forest biomass while other seasonal data were either insensitive or pointless. The promising results shown by the VSI suggest that it could be an appropriate candidate for monitoring vegetation structure from the multi-angular satellite remote sensing.
Potential of Entomopathogenic Nematodes versus Alpha-cypermethrin Against Potato Tuber Moth, Phthorimaea operculella Zeller 1873 (Lep.: Gelechiidae) in Storage Conditions
Authors: Ebrahimi Laleh , Sheikhigarjan Aziz , Ghazavi Mehran
Published: February 2021

The potato tuber moth PTM, Phthorimaea operculella, is one of the most economically important potato pests worldwide. In the present study, the potential of Steinernema feltiae and Steinernema carpocapsae for controlling PTM in potato tubers was evaluated compared to alpha-cypermethrin. Steinernema carpocapsae in both concentrations (12.6×106IJs and 6.2×106IJs) showed a lower number of emerged insects than alpha-cypermethrin (10 mg ai l-1). Alpha-cypermethrin (20 mg ai l-1) showed the highest efficacy against PTM (81.17%), S.carpocapsae (12.6×106IJs), and alpha-cypermethrin (10 mg ai l-1) showed similar efficacy (72.53%) while S. feltiae (6.2×106IJs) showed the lowest efficacy (39.04%). The results showed that S.carpocapsae in both concentrations and S. feltiae (12.6×106IJs) were efficient the same as alpha-cypermethrin (10 mg ai l-1) having no environmental and health adverse impacts issued in the chemical insecticides usage. Both concentrations of alpha-cypermethrin and S. carpocapsae showed the least tuber damage with no significant differences, while it was as high as the control (59.26%) in both concentrations of S. feltiae. This promising finding introduces EPNs as a part of the potato tuber protection program in storage. Accordingly, EPNs can be considered as an appropriate alternative to synthetic chemicals for PTM control without any residue and health problems.
Spatio-temporal Analysis of Sediment Yield Estimation Using Integrated RUSLE and GIS Technique: Case of Nashe Dam Reservoir, Abay Basin, Ethiopia
Authors: Tamiru Habtamu , Wagari Meseret
Published: February 2021

Sediment accumulation in a dam reservoir is a common happening environmental problem throughout the world. Topographic conditions, land use land cover change, the intensity of rainfall, and the soil characteristics are the major driving factors for sedimentation to occur. The effect of sedimentation in a dam reservoir is very visible in the watershed as a result of hilly topographic conditions, high rainfall intensity, thin land cover, and less soil infiltration capacity. In this paper, an integrated RUSLE and GIS technique was implemented to estimate a mean annual sediment yield based on spatial and temporal variations in Nashe dam reservoir situated in Fincha catchment, Abaya River basin, Ethiopia. Spatial and temporal estimation of mean annual sediment yield was estimated using the Revised Universal Soil Loss Equation (RUSLE) model and GIS. Historical 6-year (2014-2019) rainfall for the temporal variations and other physical factors such as soil erodibility, slope and length steepness, management and land used land cover, and support practice for spatial variations were used as sediment driving factors. The mean annual sediment yield ranges from 0 to 2712.65 t ha-1 year-1 was seen. Spatially, Very high, high, moderate, low, and very low sediment yield severity with total area coverage with 25%, 10%, 30%, 15%, and 20% in 2017, 2015, 2019, 2014, and 2018 respectively. The information about the spatial and temporal variations of the severity of sediment yield in RUSLE model has a paramount role to control the entry of sediment into the dam reservoir in this watershed. The results of the RUSLE model can also be further considered along with the watershed for planning strategies for dam reservoirs in the catchment.
Anxiety-Driven Cardiopulmonary Complaints during COVID-19 Pandemic Outbreak
Authors: Koren Ofir , Rajab Saleem , Barbour Mohammad , Shachar Moriah , Shahar Amit , Zubidat Khaled , Slim Wasim , Igbariya3 Daher , Rozner Ehud , Turgeman Yoav , Mader Einat
Published: February 2021

Background We intend to examine whether the COVID-19 outbreak influences medical decision-making (MDM) among Non-COVID patients. Method We recruit 287 patients who admit to ER department due to cardiovascular complaints. Anxiety level was measured using three questionnaires (GAD-7, Beck Inventory, and the cardiac anxiety questionnaire). A fourth survey was designed to assess MDM considerations. Results 64% of patients were male (median age 54). Almost half of the patients were found to have moderate to severe levels of anxiety.79.3% of patients reported that the outbreak influenced their MDM. 44.5% of patients sought medical care 2-3 from the onset of symptoms. Coronary artery disease was found in only 26 patients (9.1%). Almost half of the patients stated that they would have gone earlier if not for the current pandemic. Conclusion Non-COVID patients seeking medical care had a high anxiety level that directly affected decision-making and put them at unnecessary risk.
A Study on Sustainable Design for Indigo Dyeing Color in the Visual Aspect of Clothing
Authors: Lai Chih-Chun , Chang Ching-Erh
Published: February 2021

Various colors of clothing originating from synthetic dyes are presently causing serious environmental pollution problems, whereas natural dyes extracted from natural indigo plants help reduce the harm to the environment and extend the sustainable use of clothing. This study focuses on the relation between indigo dyeing colors and the environment on the basis of sustainable design. The results reveal that light colors are considered to conform to the sustainable spirit more than dark colors in different indigo colors. In fact, the recyclable light-colored indigo dyeing t-shirt is beneficial in its reuse. Indigo dyeing fabric can be decomposed by a variety of microorganisms; however, the light-colored indigo dyeing takes a short time. Light colored indigo dyeing is more resource-saving when considering dye, water and electricity costs. The results of colors and environmental protection provide scheme references to consumers or industry for clothing collocation of different indigo dyeing colors for a series of blue clothing and carry out the ideal of the sustainability and co-existence between clothing and natural resources.
A Comparison of Several Implementations of B92 Quantum Key Distribution Protocol
Authors: Anghel Catalin
Published: February 2021

This paper presents the development, comparison and analysis of several implementations of the B92 Quantum Key Distribution (QKD) protocol. In order to achieve this objective a prototype which consists of traditional (non-quantum) simulators was created, one for B92 protocol, one for B92 protocol with eavesdropper and one for B92 protocol with Quantum Bit Travel Time (QBTT) eavesdropper detection method. The principles of quantum mechanics were studied, as a foundation of quantum cryptography, for the realization of simulation programs that were written in C ++, focusing mainly on the B92 protocol and QBTT eavesdropper detection method. We compared the Quantum Bit Error Rate (QBER) for implementation of B92 protocol without eavesdropper, B92 protocol with eavesdropper and B92 protocol with QBTT eavesdropper detection method and found that QBTT eavesdropper detection method significantly reduces the QBER from the final key.
Targeting the Reconsolidation of Licit Drug Memories to Prevent Relapse: Focus on Alcohol and Nicotine
Authors: Barak Segev , Goltseker Koral
Published: February 2021

Alcohol and nicotine are widely-abused legal substances worldwide. Relapse to alcohol or tobacco seeking and consumption after abstinence is a major clinical challenge, and is often evoked by cue-induced craving. Therefore, disruption of the memory for the cue-drug association is expected to suppress relapse. Memories have been postulated to become labile shortly after their retrieval, during a “memory reconsolidation” process. Interference with the reconsolidation of drug-associated memories has been suggested as a possible strategy to reduce or even prevent cue-induced craving and relapse. Here, we surveyed the growing body of studies in animal models and in humans assessing the effectiveness of pharmacological or behavioral manipulations in reducing relapse by interfering with the reconsolidation of alcohol and nicotine/tobacco memories. Our review points to the potential of targeting the reconsolidation of these memories as a strategy to suppress relapse to alcohol drinking and tobacco smoking. However, we discuss several critical limitations and boundary conditions, which should be considered to improve the consistency and replicability in the field, and for development of an efficient reconsolidation-based relapse prevention therapy.
Machine Learning Model for Diagnosing the Stage of Liver Fibrosis in Patients With Chronic Viral Hepatitis C
Authors: Tsvetkov Valeriy , Tokin Ivan , Lioznov Dmitriy
Published: February 2021

Aim. The purpose of the work was the development of a machine learning model for diagnosing the stage of liver fibrosis in patients with chronic viral hepatitis C according to the data of routine clinical examination. Materials and methods. A total of 1240 patients with chronic viral hepatitis C was examined. A set of data obtained from 689 patients balancing by the stage of liver fibrosis was used for developing and testing machine learning models. 9 routine clinical parameters were selected as the most important predictors for determining the likelihood of liver fibrosis the 3–4 stages presence: age, height, weight and body mass index of the patient, the number of platelets in the clinical blood test, levels of alanine transaminase, aspartate transaminase, gamma-glutamyltransferase, and total bilirubin in a biochemical blood test. Results. The accuracy of the developed method for determining the 3–4 stages of liver fibrosis in patients with chronic viral hepatitis C in comparison with the «gold standard» of diagnosis (liver biopsy) was 80.56% (95% CI: 69.53–88.94%), sensitivity — 66.67%, specificity — 94.44%. Conclusion. The developed method is an alternative to more expensive and geographically inaccessible studies. The method does not require the purchase of additional equipment or software, as well as additional laboratory tests, when used in real clinical practice. The introduction of the method into clinical practice can help to solve the problem of low material and territorial availability of diagnostic tests and allow determining the stage of liver fibrosis in patients with chronic viral hepatitis C.
Orthogeriatric Care: Reviewing Improvements in Outcomes
Authors: Tarazona-Santabalbina Francisco José , Ojeda-Thies Cristina , Figueroa Rodríguez Jesús , Cassinello-Ogea Concepción , Caeiro José Ramón
Published: February 2021

Hip fractures are an important socio-economic problem in western countries. Over the past 60 years orthogeriatric care has improved the management of older patients admitted to hospital after suffering hip fractures. Orthogeriatric co-management units have increased quality of care, reducing adverse events during acute admission, length of stay, both in-hospital and mid-term mortality, as well as healthcare and social costs. Nevertheless, a large number of areas of controversy regarding the clinical management of older adults admitted due to hip fracture remain to be clarified. This narrative review, centered in the last 5 years, combined the search terms “hip fracture”, “geriatric assessment”, “second hip fracture”, “surgery”, “perioperative management” and “orthogeriatric care”, in order to summarise the state of the art of some questions such as the optimum analgesic protocol, the best approach for treating anemia, the surgical options recommendable for each type of fracture and the efficiency of orthogeriatric co-management and functional recovery.
The Resonant and Normal Auger Spectra of Ozone
Authors: Taioli Simone , Simonucci Stefano
Published: February 2021

In this work we outline a general method for calculating Auger spectra in molecules, which accounts for the underlying symmetry of the system. This theory starts from Fano’s formulation of the interaction between discrete and continuum states and generalizes this formalism to deal with the simultaneous presence of several intermediate quasi-bound states and several non-interacting decay channels. Our theoretical description is specifically tailored to resonant autoionization and Auger processes, and includes explicitly the incoming wave boundary conditions for the continuum states and an accurate treatment of the Coulomb repulsion. This approach is implemented and applied to the calculation of the K−LL Auger and autoionization spectra of ozone, which is a C2v symmetric molecule, whose importance in our atmosphere to filter out radiation has been widely confirmed. We also show the effect that the molecular point group, and in particular the localization of the core-hole in the oxygen atoms related by symmetry operations, has on the electronic structure of the Auger states and on the spectral lineshape by comparing our results with experimental data.
How Accurate are WorldPop-Global Gridded Population Data at the Cell-Level?: A Simulation Analysis in Urban Namibia
Authors: Thomson Dana R. , Leasure Douglas R. , Bird Tomas , Tzavidis Nikos , Tatem Andrew J.
Published: February 2021

Disaggregated population counts are needed to calculate health, economic, and development indicators in Low- and Middle-Income Countries (LMICs), especially in settings of rapid urbanisation. Censuses are often outdated and inaccurate in LMIC settings, and rarely disaggregated at fine geographic scale. Modelled gridded population datasets derived from census data have become widely used by development researchers and practitioners; however, none of these datasets have been evaluated for accuracy of population estimates at the grid cell-level. This is because the finest-scale population figures generally available to data producers are those input into gridded population models and disaggregated to smaller grid cells (e.g., 100x100m). We simulate a realistic "true" 2016 population in Khomas, Namibia, a majority urban region, and introduce realistic levels of outdatedness (over 15 years) and inaccuracy in slum, non-slum, and rural areas. We then aggregate these simulated realistic populations by census and administrative boundaries (to mimic census data), and generate 32 gridded population datasets that are typical of a LMIC setting using WorldPop-Global's gridded population approach. We evaluate the cell-level accuracy of these simulated WorldPop-Global datasets, using the original "true" population as a reference. In our simulation, we found large cell-level errors, particularly in urban cells, driven by WorldPop-Global's use of average population densities in large areal units to determine cell-level population densities. Age, accuracy, and aggregation of the input data did play a primary role in these errors. We suggest incorporating finer-scale training data into gridded population models generally, and WorldPop-Global in particular (e.g., from simulated populations, routine household surveys, or slum community profiles), and use of new building footprint datasets as a covariate to improve cell-level accuracy of gridded population data. It is important to measure cell-level accuracy of all gridded population datasets, especially if they are to be used for monitoring key development indicators.
Efficient Visible Active Ternary Bi2MoO6-rGO-TiO2 Composite Material for Photodecomposition of Ofloxacin
Authors: Raja Annamalai , Son Namgyu , Kang Misook
Published: February 2021

The ternary Bi2MoO6-reduced graphene oxide (rGO)-TiO2 catalyst were synthesized using a simple hydrothermal method. The improvement of the photocatalytic decomposition efficiency of Bi2MoO6-rGO-TiO2 composite is 92.3% than the pure and binary photocatalyst. The effects of operational parameters like catalyst ratio, the different catalyst, different ratio rGO and different pH, have been analyzed. As prepared ternary photocatalyst is low Photoluminescence and high photocurrent density responsible, it exhibited that photon-induced electron and hole-recombination were suppressed and also charged separation is effective. The present study shows the rGO is an excellent electron transfer performance and enhanced the photocatalytic reaction stability.
Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia
Authors: Rodriguez Princess D. , Paculova Hana , Kogut Sophie , Heath Jessica , Schjerven Hilde , Frietze and Seth
Published: February 2021

Non-coding RNAs (ncRNAs) comprise a diverse class of non-protein coding transcripts that regulate critical cellular processes associated with cancer. Advances in RNA-sequencing (RNA-Seq) have led to the characterization of non-coding RNA expression across different types of human cancers. Through comprehensive RNA-Seq profiling, a growing number of studies demonstrate that ncRNAs, including long non-coding RNA (lncRNAs) and microRNAs (miRNA), play central roles in progenitor B-cell Acute Lymphoblastic Leukemia (B-ALL) pathogenesis. Furthermore, due to their central roles in cellular homeostasis and their potential as biomarkers, the study of ncRNAs continues to provide new insight into the molecular mechanisms of B-ALL. This article reviews the ncRNA signatures reported for all B-ALL subtypes, focusing on technological developments in transcriptome profiling and recently discovered examples of ncRNAs with biologic and therapeutic relevance in B-ALL.
The Diversity, Composition, and Metabolic Pathways of Archaea in Pigs
Authors: Deng Feilong , Li Yushan , Wei Xiaoyuan , Wang Xiaofan , Howe Samantha , Li Hua , Zhao Jiangchao , Li Ying
Published: February 2021

Archaea are an essential class of gut microorganisms in humans and animals. Despite the substantial progress in gut microbiome research in the last decade, most studies have focused on bacteria, and little is known about archaea in mammals. In this study, we investigated the composition, diversity, and functional potential of gut archaeal communities in pigs by re-analyzing a published metagenomic dataset including a total of 276 fecal samples from three countries: China (n=76), Denmark (n=100), and France (n=100). For alpha diversity (Shannon Index) of the archaeal communities, Chinese pigs were less diverse than Danish and French pigs (P<0.001). Consistently, Chinese pigs also possessed different archaeal community structures from the other two groups based on the Bray-Curtis distance matrix. Methanobrevibacter was the most dominant archaeal genus in Chinese pigs (44.94%) and French pigs (15.41%), while Candidatus Methanomethylophilus was the most predominant in Danish pigs (15.71%). At the species level, the relative abundance of Candidatus Methanomethylophilus alvus, Natrialbaceae archaeon XQ INN 246, and Methanobrevibacter gottschalkii were greatest in Danish, French, and Chinese pigs with a relative abundance of 14.32%, 11.67%, and 16.28%, respectively. In terms of metabolic potential, the top three pathways in the archaeal communities included the MetaCyc pathway related to the biosynthesis of L-valine, L-isoleucine, and isobutanol. Interestingly, the pathway related to hydrogen consumption (METHANOGENESIS-PWY) was only observed in archaeal reads, while the pathways participating in hydrogen production (FERMENTATION-PWY and PWY4LZ-257) were only detected in bacterial reads. Archaeal communities also possessed CAZyme gene families, with the top five being: AA3, GH43, GT2, AA6, and CE9. In terms of antibiotic resistance genes (ARGs), the class of multidrug resistance was the most abundant ARG, accounting for 87.41% of archaeal ARG hits. Our study reveals the diverse composition and metabolic functions of archaea in pigs, suggesting that archaea might play important roles in swine nutrition and metabolism.
Bringing the User Back in the Building: An Analysis of ESG in Real Estate and a Framework to Guide Future Research
Authors: Kempeneer Shirley , Peeters Michaël , Compernolle Tine
Published: February 2021

Investors are currently obliged to take ESG (Environment, Social, Governance) issues into consideration as part of their fiduciary duty. As such, it becomes increasingly important to identify sustainable investments that hold financial value as well. A sector where this is especially underdeveloped is real estate. This has a lot to do with the obfuscated conceptualization of ESG. The article identifies key gaps in literature and practice, and provides a framework to further the understanding of how ESG factors can add societal and financial value in the real estate sector. A key premise of the article is that the user in the building is grossly overlooked. Drawing on insights from behavioral social science and environmental psychology, the paper explains the role of the user in improving buildings’ ESG, also taking into account the investment value. To conclude, the article makes the case that the transition to user-centered smart real estate is the solution to improving both the environmental (E) and social (S) sustainability of buildings, as well as their investment value. Therefore, practitioners and academics are encouraged to critically evaluate and contextualize the ESG framework they are using, as well as the extent to which users are considered and smart technology is employed.
New Study of Existence and Dimension of the Set of Solutions for Nonlocal Impulsive Differential Inclusions With Sectorial Operator
Authors: Sessa Salvatore , Alsarori Nawal , Ghadle Kirtiwant , Saleh Hayel
Published: February 2021

In this article, we are interested in a new generic class of nonlocal fractional impulsive differential inclusions with linear sectorial operator and Lipschitz multivalued function in the setting of finite dimensional Banach spaces. By modifying the definition of PC-mild solutions initiated by Shu, we succeeded to determine new conditions that sufficiently guarantee the existence of the solutions. The results are obtained by combining techniques of fractional calculus and fixed point theorem for contraction maps. We also characterize the topological structure of the set of solutions. Finally, we provide a demonstration to address the applicability of the theoretical results.
Some Remarks on Fuzzy Hilbert Spaces
Authors: Lorena Popa , Sida Lavinia
Published: February 2021

The aim of this paper is to determine a suitable definition for the concept of fuzzy Hilbert space. In order to achieve this, we firstly focused on various approaches from the already-existent literature. Then we considered another approach to the notion of fuzzy inner product and analysed its properties.
Integración de grupos de trabajo con apoyo de C4.5
Authors: Soltero-Romero Marlene , Rodas-Osollo Jorge
Published: February 2021

El perfil de una persona respecto a su desempeño al realizar diversas actividades en áreas diferentes, en lo individual o trabajando en equipo, es de suma importancia para un negocio u organización, ya que conociendo los perfiles de las personas se pueden integrar grupos de trabajo más eficientes. De las pruebas de perfilado de personalidad, la DISC es una de las más utilizadas por los departamentos de recursos humanos. Sin embargo, todos los test de perfilado son altamente subjetivos, por lo que con frecuencia un perfil puede ser indeterminado. En este artículo se comparte el resultado de utilizar el C4.5, un algoritmo de clasificación supervisada, como apoyo a los departamentos de recursos humanos y se determina, de acuerdo al test de personalidad DISC, la más adecuada integración.
Pleasure As a Subject of Logic. To the Interpretation of Philebus. Part I
Authors:   Lomonosov Moscow State University, Bugai Dmitry V.
Published: February 2021

The task of the paper is to determine what is the philosophical meaning of Plato’s Philebus. To define the meaning is to show which way of understanding Phile­bus is the most fruitful, most fully grasping and revealing what forms the sub­stantive core of Plato’s text. It’s no secret that the meaning of Philebus is not at all self-evident. From our point of view, the main subject of the dialogue lies not in the plane of ontology, but in ethics, and what is taken for ontological aspects in Philebus is much more related to the logical and methodological conditions for solving the main ethical problem. Therefore, in this article an attempt was made to show that the key themes of Philebus(the problem of the one-many, the relationship of the four kinds of beings, the theory of false pleasures) are inter­nally related. The question of the relationship between the one and the many is raised in connection with the clarification of the question of the logical status of pleasure. Division into four kinds (limit, unlimited, mixture, reason) is the ful­fillment of the methodological requirement for the necessity of division. The ana­lysis of pleasures following this methodological introduction examines pleasure in an entirely new light, in the light of truth/falsity.
Konjaku Monogatari-shūin the History of Japanese Religious Philosophy
Authors:   Institute of Philosophy, Russian Academy of Sciences, Trubnikova Nadezhda N. ,   Russian Presidential Academyof National Economy and Public Administration, Babkova Maya V. ,   Institute of Oriental Studies RAS,   Russian Presidential Academy of National Economyand Public Administration, Kolyada Maria S. ,   Institute of Philosophy, Russian Academy of Sciences,   Russian Presidential Academyof National Economy and Public Administration
Published: February 2021

The article summarizes the results of the historical and philosophical research “Collection of ancient stories” (Konjaku monogatari-shū, 1120s). This largest Ja­panese collection of setsuwa tales paints a picture of world history from the era of Buddha to the age of mappō, “Decline of Buddhist Teaching”, tracing the milestones in the spread of Buddhism in India, China and Japan. The two most important Buddhist attitudes – the world is impermanent and at the same time each event is embedded into a universal system of cause-and-effect rela­tionships – are reflected not only at the level of the content of an individual story, but also at the level of connecting stories into a holistic narrative. All events have instructive educative? meaning; everyday experience always leads to the same conclusions as the teachings of Buddha. In this experience, a person in­evitably makes some connections – with other people, living and dead, with ani­mals and spirits, gods and buddhas – and these connections involving this person in the cycle of birth and death, if properly understood, provide the basis for liber­ation. The narrator draws a line between a proper and an inappropriate under­standing of what is happening, talking about the “immeasurable” (grief, joy, fear, etc.), and thus allows the readers to find the “measure”, kagiri, in their relation to what is happening. The march of time can be understood both as a general move­ment from the best to the worst, and – on small intervals – as a reverse move­ment from grief to happiness, from misunderstanding to understanding. A person is free to choose which events to keep in memory and which to forget; people make this choice whilst instructive storytelling, and setsuwa tradition preserves it.
Philosophical and Mystical CultureAs an Alternative to Modern Civilization of Consumption: To Have or To Be?
Authors:   Institute of Social Sciences and International Relations, Sevastopol State University, Zhirtueva Natalia S.
Published: February 2021

The comparative analysis of philosophical and mystical culture and the modern consumer society is realized in the article. The philosophical and mystical cul­ture reveals the spiritual essence of man, develops awareness, willpower and the highest spiritual qualities of the personality. The society of consumption dis­torts the essence of man, develops over-consumption, consumerism, escapism, transmutes a person into a thing. Mankind is in a state of choice, at the point of bifurcation, which determines the future of civilization. The philosophical and mystical worldview underlies idealistic and ideational cultures, which should re­place the modern sensual culture (the terms of P. Sorokin)
Interest of a standardized hypnotic message for the reduction of pain and anxiety in cancer patients treated by capsaicin patch for neuropathic pain: A randomized-controlled trial
Authors: Etienne Rémi , Laurent Myriam , Henry Aline , Bioy Antoine , Salleron Julia , Huin-Schohn Cécile , Cretineau Nathalie
Published: February 2021

BackgroundNeuropathic pain is characterised by spontaneous painful symptoms. Medical therapies include the use of a capsaicin 8% patch (Qutenza ®, Grünenthal Gmbh, Germany), and patients may experience a sharp burning sensation at application and removal of the patch. This study aimed to evaluate the impact of playing a standardized hypnosis recording during application, on the pain and anxiety induced by capsaicin treatment.MethodsIn a randomized-controlled trial, we assessed the benefits of the intervention firstly on pain and secondly on anxiety, as measured using numerical rating scales. All patients had application of the capsaicin patch, including the possibility for the patient to apply a cold patch. Participants were randomly assigned to one of 3 groups, namely the “Standard group” (no intervention), “Hypnosis group”, in which a standardized hypnotic message was played during application, or the “Music group” in which relaxing music was played during application of the patch.ResultsSixty-nine patients were included. Overall, there was no significant difference in pain scores between groups (p = 0.355). Compared to standard application, anxiety was significantly lower in the hypnosis group after application (p = 0.007), with no significant difference between the standard and music arms (p = 0.271), or between the hypnosis and music arms (p = 0.423).ConclusionsListening to a standardized hypnotic message during application of a capsaicin patch was found to significantly lower anxiety. These findings indicate that the use of a hypnotic message can reduce discomfort and warrant its evaluation in other indications of pain or anxiety during treatment procedures.Trial Registration : NCT02822625