bluuebunny/crossref_metadata_2025 huggingface dataset:
dilemma of chronic kidney disease of unknown origin
Authors: Sowah Shadrack O , Amaama Leticia A. , Okyere Perditer , Adoba Prince , Afrifa Justice , Donkor Irene , Ametepe Samuel , Ephraim Richard KD
Published: March 2024

Over the past two decades, cumulative increases in the prevalence of chronic kidney disease (CKD) have been observed in selected geographic areas in several countries. The etiology of this CKD cannot be attributed to known or traditional causes or risk factors, and the term chronic kidney disease of unknown etiology (CKDu) has been used to describe this entity. These regional endemic nephropathies are commonly known as CKD of unidentified cause (CKDu) or CKD of nontraditional etiology (CKDnt) and, more recently, Chronic interstitial nephritis of agricultural communities (CINAC). Unlike the traditional causes of CKD (i.e., Hypertension, Diabetes, chronic glomerulonephritis, etc), CKDu has been associated with agricultural and arid regions. Also, the socioeconomic state of those regions is key. This review addresses the present status of the knowledge for different aspects of this regional health problem as well as summarizes available evidence on the risk factors, epidemiology, clinical features, diagnosis, treatment, and prevention of CKDu. It will also highlight the reasons why Africa should be concerned about this condition. Using the keywords “Africa, CKD of unknown origin,” a literature search was conducted on PubMed, Scopus, and Google Scholar, focusing on the research published between 2000 and 2022. Results from the literature show that predisposition to heat stress and dehydration, subclinical rhabdomyolysis, toxins from alcoholic beverages, agrochemicals, and heavy metals all result in acute kidney injury, and repeated exposures to these factors can then cause CKDu. Earlier studies in Sri Lanka nephropathy by Nanayakkara and his team in 2014 identified that a genetic variant of SLC13A3 (sodium-dependent dicarboxylate transporter member 3) is associated with CKDu. Later research conducted in 2015 discovered KCNA10 (a voltage-gated potassium channel) also as a gene implicated in CKDu; these genetic variances were discovered to be common among the populace suffering from kidney diseases, hence suggesting that, people with these genes have a high risk of developing kidney disease. Predisposition to heat stress and dehydration, subclinical rhabdomyolysis, and toxins from alcoholic beverages, agrochemicals, and heavy metals all results in acute kidney injury, and repeated exposures to these factors can then cause CKDu. Also, certain genes have been found to be associated with CKDu.
Editorial
Authors: Konstantinou Thaleia , Knaack Ulrich
Published: March 2024

The first issue of volume 11 of JFDE elaborates on several topics related to façade design and engineering, focusing on façade systems, their construction, properties, and performance.

The topic of prefabrication in façade construction is one of the themes emerging from this issue. The importance of prefabrication is growing in the building industry as it has the potential to improve productivity by allowing faster, high-quality, and cost-effective construction while reducing risks related to onsite construction. Different articles touch on this topic from varying perspectives. In the context of decarbonization and the large number of buildings to be renovated, prefabrication for energy retrofits is a relevant topic. One notable article presents the development and evaluation of prefabricated timber-based façade modules. The results showed significant energy savings and effective vapor release of the prefabricated façade system. Furthermore, prefabrication and pre-engineering of systems require a paradigm shift in design and engineering practices towards more integrated approaches. A Kit-of-Part (KoP) approach to façade design employed by the authors of a different article enables an architect-led design team to validate design options through digital design tools based on a pre-engineered set of components. Information about the products included in the tool includes performance, cost, and environmental impact.

Focusing further on the properties of façade components, a paper in this issue investigates large-scale applications in building design regarding the aluminum used in façades and underlines the environmental benefits to be gained from reducing the use of raw materials, with particular emphasis on a sustainable approach to façade design. Finally, the issue addresses shading as an essential component of façade function, examining the influence of different shading devices on both performance and aesthetic aspects of the façade.

Overall, the issue provides insights into contemporary trends in façade design, emphasizing the role of pre-engineering and evaluating façade components in contributing to the future of the construction industry.
Prefab Facades – From Prototype to Product?
Authors: Rammig Lisa , Zani Andrea , Murphy Tim , Paparo Isabelle , Hildebrand Linda , Abbring Steve , Kopreck Derick , Wu Christine , Lee Joyce , Turpin Kate
Published: March 2024

Building envelopes are not only the prime element of the exterior aesthetic quality of buildings; they have also become a major driver both for building construction cost and operational performance. The importance of prefabrication is growing in the building industry as it allows faster, high-quality, and cost-effective construction while reducing risks associated with onsite labour. Although prefabrication for structural components is a relatively recent development, it has been widely used in the manufacturing of building envelopes for many years, particularly in the case of unitized curtain wall systems. However, whether using prefabricated components or not, façade design development remains a challenge due to the need for façade engineers to rapidly develop technically viable and financially feasible solutions that achieve the desired architectural design intent. Particularly at the early stages of the design process, the turnaround for multiple iterations is often fast-paced, and abortive work is, therefore, not uncommon.
This paper outlines an approach to addressing this challenge, attempting to bridge the gap between façade design, fabrication, and installation. A new design approach and tools are presented that allow designers to iteratively validate concepts based on a pre-engineered system that is optimized for performance and take fabrication, transport, installation costs, maintenance, and circularity into account. As a result, the tool/design workflow will ensure consistent quality, meeting budgets and timelines while enhancing material efficiency and fostering energy-conscious and circular envelope design approaches.
Encryption using True Random Number
Authors: Kavitha I  , Harimadav S  , Karthigeyan P  , Kirubanithi R  , Kreshanth S V
Published: March 2024

In moment's connected digital geography, data security and sequestration have come consummate enterprises. Traditional encryption ways frequently calculate on mock arbitrary number creators (PRNGs) to induce encryption keys, which are deterministic and vulnerable to attacks. This design proposes a new approach to enhance data encryption by exercising true arbitrary number creators (TRNGs) for generating encryption keys. In this work, a secure optic ultrafast arbitrary number creator grounded on arbitrary ray gamut’s was demonstrated. Unlike the usual system of recording ray intensity over time, the arbitrary ray diapason under each pump palpitation was recorded and converted into arbitrary figures through post-processing. Approaches in three different confines — space, diapason and time were used to increase the rate of arbitrary number generation. The randomness of performing arbitrary bit aqueducts was vindicated by the NIST statistics tests
An All-Terrain Intelligent Autonomous Vehicle with Sensor Fusion Based Navigation Capabilities
Authors: Gadakh Sankalp Ashok  , Hase Alok Dattatraya  , Bagul Akshay Arvind  , Prof. Dighe Y. N.
Published: March 2024

An automated defense robot building is planned, that has a laser gun attached, which is utilized for pointing laser rays to destroy the target object. One of the most important things about these robots is that they have the capability to perform missions remotely in the field, without any actual danger to human lives. In the proposed system, a robot is developed that is controlled through Microcontroller. For the aiming purpose and to view the road and the surroundings in which the robot is travelling, wireless cameras are installed. Radio frequency can be used to control the robot.
These defense robots used in military are usually employed with the integrated system including gripper, cameras and sensors. This is specially designed for defense robotic system to save human life and protect the country from enemies. In the existing systems, personal computer using ZigBee protocol is used to monitor the robot.
Sanjad-Sakati Syndrome in a 35-day-old Iraqi Infant: A Case Report
Authors: Al Ajeli Majeed H.
Published: March 2024

Sanjad-Sakati syndrome is a rare autosomal recessive genetic disorder that presents solely in Arabian people. Our case was reported from the Fallujah Teaching Hospital for Women and Children in Fallujah, Iraq. This syndrome is associated with hypoparathyroidism, growth retardation, atypical facial appearance, and a variable degree of mental retardation. It is usually caused by genetic mutations of the tubulin-folding cofactor E (TBCE; 604934), which is located on the 1q42.3 chromosome. This case was confirmed by a genetic study which revealed a pathogenic variant in the homozygous state in the TBCE gene. Typically, the physical features of this case involve microcephaly, long and narrow face, beaked nose, deep-set eyes, large ears, thin lips, long philtrum, micrognathia, and small hands and feet. Although Sanjad-Sakati syndrome is an incurable disease, early diagnosis helps with appropriate palliative treatment of the patient, reducing other associated metabolic and electrolyte disturbances, and allows for a genetic study and counseling of the family, especially in our society due to the high rate of consanguinity.
Treading on the Tiger’s Tail: Chinese Wuxia and Japanese Jidaigeki Action Films Reacting to State Censorship in the 1930s and 1940s
Authors: Pan Zerui
Published: March 2024

This article highlights the relationship between wuxia (martial heroes) and jidaigeki (period drama) action films and state censorship in the 1930s and 1940s. I first introduce readers to key East-Asian literary conventions that portray righteous warriors who incarnate their moral codes with swords. I then illustrate the political contexts in 1930s China and 1940s Japan which caused the popular film genres of wuxia and jidaigeki to become politically problematic and therefore strictly censored. I closely examine director Bu Wancang’s 1931 wuxia film A Spray of Plum Blossoms and Kurosawa Akira’s jidaigeki 1945 film Treading on the Tiger’s Tail, investigating creative solutions each director found in order to release their respective films despite censorship pressures. There are three inventions both directors pioneered in their work, namely “ostensible exactness” in setting; “patriotic warriors” in characterization; and “swordless fights” in presenting spectacular action scenes. I argue that although these solutions failed to restore both genres back to their former popularity, Kurosawa’s film paved the way for the success of his world-class jidaigeki in the 1950s, and Bu’s wuxia led to the emergence of kung fu films in the 1960s. My critical analysis underscores the innovative creativity of Chinese wuxia and Japanese jidaigeki films while calling attention to the artistic and cultural legacies of these two popular cinematic genres. The comparison demonstrates how film censorship may undermine or even destroy traditions that have a long history and deep cultural roots.
Use of CRISPR/Cas9 Gene Editing Methods to Investigate the Mechanism of Trem2-Dependent Gene Expression in Macrophages
Authors: Alishala Mohnish
Published: March 2024

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) is a surface receptor expressed in macrophages during tissue injury. This receptor plays a role in driving phagocytosis and dampening inflammation. Because of this, it plays a large part in diseases such as Alzheimer’s disease, liver fibrosis, and metabolic syndrome. Each of these diseases all have a population of TREM2-expressing macrophages that does not exist in healthy tissue. However, the exact pathway in which TREM2 is involved in these diseases is rather unknown. Macrophage gene expression is regulated by a variety of transcription factors such as ATF3 and TFEB. These transcription factors have been suggested to be involved in some of the disease processes mentioned above by RNA-seq or ChIP-seq experiments.The research question we addressed was how these two transcription factors directly affectvtranscription in macrophages, specifically in the TREM2 pathway. CRISPR/Cas9 gene editing was used to generate loss of function alleles for each transcription factor. RNA-seq was then used to compare gene expression to define the gene-specific transcriptional roles of each factor and determine whether they play roles downstream of TREM2 signaling.Results showed that Atf3 knockout had very few genes upregulated or downregulated in the RNA seq compared to Trem2 knockout. Tfeb, on the other hand, had 13 genes in common with Trem2 knockout that were expressed lower than the control and 10 genes in common expressed higher than the control. The Tfeb knockout had no difference in Trem2 expression between the knockout population and control, further providing evidence that Tfeb is located downstream of Trem2. Because Trem2 levels stayed consistent in the Tfeb KO, it is likely that some of the effects of Trem2 on the macrophage disease population genes are directly mediated through Tfeb.
Building Trust in the AI Ecosystem by Re-Evaluating Public Perception
Authors: Flores Christian
Published: March 2024

Artificial intelligence systems leverage large datasets with iterative processing algorithms that identify patterns to create an additional layer of expertise. This transformational power operates in tandem with ethical risks. The dominant narrative behind AI is simultaneously stigmatized and misunderstood: with exponential growth of the ubiquitous technology leaving public awareness in the dust, it's becoming increasingly important to balance enthusiasm for AI's enormous promise with a sober understanding of its moral risks. This study seeks to characterize the public opinion of AI in high-risk, domain-specific applications. To that end, a poll was administered to American adults. The results of the study reveal that the great majority of survey respondents have a neutral or optimistic perspective on AI in particular high-risk domains. The study concludes by presenting a standard heuristic for understanding public perception where ethics may fail to preserve a human factors' approach. In this way, researchers and developers can undertake coordinated efforts to mitigate the harm caused by AI while promoting rational optimism in vulnerable populations.
LEVANTAMENTO COM OS EGRESSOS DOS CURSOS DE ADMINISTRAÇÃO E ADMINISTRAÇÃO COM LINHA DE FORMAÇÃO EM COMÉRCIO EXTERIOR SOBRE A FORMAÇÃO SUPERIOR OPORTUNIZADA PELA UNIVERSIDADE ESTADUAL DE PONTA GROSSA
Authors: Moletta Sirlei , da Silva Juvancir , Lara Luiz Fernando , Martins Roberto Rosemary Aparecida , do Rocio Oliveira Marilisa , Maier Biscaia Rubia Carla , Scalise Taques Fonseca Carolina , Guimarães Moro Silas
Published: March 2024

Considerando a importância econômica e social em uma região geográfica de um país que os cursos de formação superior proporcionam como exemplo, na produtividade das empresas pelo aumento de profissionais capacitados com a oferta de diversos serviços relacionados com a formação superior, assim como, os incrementos imediatos e permanentes na renda dos egressos e dos demais trabalhadores das empresas. Nesse contexto, o artigo teve por objetivo geral realizar um levantamento para mapear a realidade dos egressos do curso de Administração e Administração com linha de formação em Comércio Exterior no período entre dezembro de 2021 e dezembro de 2023 em relação à formação oportunizada pela Universidade. Por meio deste levantamento foi possível entender pontos fracos e fortes da formação oferecida e melhorar o relacionamento do curso com os egressos.
PERSPECTIVAS DE PRIVACIDADE EM MARKETING: UMA REVISÃO DE LITERATURA SOBRE ABORDAGENS CONCEITUAIS A LUZ DA LEI GERAL DE PROTEÇÃO DE DADOS PESSOAIS
Authors: Merenda Richarde Ana Paula
Published: March 2024

O contexto de crescimento tecnológico e o desenvolvimento de estratégias de marketing baseadas em dados do consumidor, bem como as pressões regulamentais por privacidade de dados, fez emergir um vasto campo de estudos sobre privacidade em Marketing. Dessa forma, este estudo apresenta resultados de um estudo revisional da literatura dos últimos dez anossobre o tema. O objetivo deste estudo foi analisar as pesquisas sobre privacidade em marketing, sintetizando perspectivas e discutindo-as a luz da Lei Geral de Proteção de Dados Pessoais (LGPD). A análise desses estudos, permitiu a classificação em quatro pilares de influência: antecedentes contextuais, características da empresa, variáveis individuas e variáveis comportamentais ou de resultado. A contribuição deste artigo centra-se em discutir a relevância dos dados para a gestão de marketing, bem como a atualidade do tema discutido para organizações, consumidores e gestores de marketing. Conclui-se apresentando direcionamentos a estudos futuros de maneira interdisciplinar apontando reflexões e possíveis caminhos a serem percorridos por pesquisadores, a luz das transformações no cenário da LGPD e da pandemia de Coronavírus, que acelerou a adoção de plataformas online.
INVESTIGAÇÃO TEÓRICA SOBRE FINTECHS À LUZ DA GESTÃO DA INOVAÇÃO EM MPE’S E A TEORIA DO CRESCIMENTO DA FIRMA DE PENROSE
Authors: Serpe Luís Filippe , Mussi Szabo Cherobim Ana Paula
Published: March 2024

O aumento da competitividade das organizações em um cenário global exige o desenvolvimento de estratégias que sustentem o processo de expansão a longo prazo; em particular com empresas de micro e pequeno portes. Assim, a gestão da inovação e a teoria do crescimento da firma emergem como propostas para o sucesso das organizações. A gestão da inovação, que se concentra na criação e implementação de novas ideias, produtos e processos, tornou-se um diferencial competitivo. Ao mesmo tempo, a teoria do crescimento da firma, que explora como as empresas expandem suas operações ao longo do tempo, oferece insights sobre como as organizações podem sustentar e ampliar seu alcance. A interseção desses dois temas é onde reside uma abordagem dinâmica e inédita para a pesquisa em Administração. Este trabalho se propõe a explorar as possibilidades teóricas de se relacionar os dois eixos de estudo, de forma a buscar pesquisas emergentes na área de Administração. Para tanto, foi utilizada uma abordagem de ensaio teórico, buscando traçar uam pesquisa qualitativa e de revisão do estado da arte sobre os temas. Os resultados demonstraram que existem ainda várias alternativas de estudo inexploradas, e este ineditismo pode trazer benefícios tanto à comunidade acadêmica quanto às organizações onde tais pesquisas forem desenvolvidas.
O PROTAGONISMO DA MULHER NA GESTÃO EMPRESARIAL: UMA ANÁLISE EM EMPRESAS DE TELÊMACO BORBA E REGIÃO
Authors: da Silva dos Santos Ana Carolina , Moletta Juliana
Published: March 2024

Este estudo teve como objetivo analisar as dificuldades das mulheres no protagonismo empresarial em Telêmaco Borba e região. A metodologia utilizada consistiu em pesquisa predominantemente quantitativa, de caráter exploratório, em que o instrumento de coleta de dados utilizado foi elaborado com base em uma revisão sistemática de literatura, após a aplicação foi realizado o teste no Alpha de Crombach, para a análise da confiabilidade. Instrumento foi aplicado a uma amostra de 69 mulheres em diferentes ocupações, como, registradas e em cargos de liderança e sem cargo de liderança, empreendedoras e outras. Para análise dos resultados foi realizada análise de estatística descritiva e de correlação. Os resultados apontam que o fator que dificulta o protagonismo das mulheres no mercado de trabalho é a Demanda Familiar seguido por Preconceito por gênero, Falta de reconhecimento da alta administração e falta de autoconfiança.
GESTÃO DO CONHECIMENTO ORGANIZACIONAL NO PROCESSO LOGÍSTICO
Authors: da Silva Juvancir , Pereira Leite Rodrigo
Published: March 2024

A organização que não reconhece que seus conhecimentos são importantes e não se preocupa com a gestão destes conhecimentos, muitas vezes é afetada em seus processos de trabalho com atrasos, retrabalho e desorganização de informações, o que gera perda de recursos e afeta a competitividade da organização. Considerando tais informações, surgiu o problema, como a gestão do conhecimento pode ser utilizada para beneficiar o processo logístico? É neste sentido que o objetivo geral do artigo foi realizar um diagnóstico da gestão do conhecimento nos processos relacionados com a gestão de estoque, controle e expedição e propor soluções com a utilização de técnicas de gestão do conhecimento. Para alcançar o objetivo foram aplicadas duas técnicas de gestão do conhecimento, a narrativa para registrar experiências dos colaboradores e a técnica de mapeamento de processo. O estudo evidenciou o entendimento que os conhecimentos dos colaboradores são parte fundamental para o setor avaliado, e que eles possibilitam que iniciativas sejam tomadas para evitar desperdícios de recursos, tornando a organização mais eficiente.
VIVÊNCIAS DA EXTENSÃO NA COMUNIDADE: RELATOS DO PROGRAMA LAGEIS-ADM
Authors: Maier Biscaia Rubia Carla , da Costa Schier Carlos Ubiratan , de Almeida Rocha Joselton José , Queji Lívio Marcel , do Rocio Oliveira Marilisa , Moro Silas
Published: March 2024

Este artigo discorre sobre as experiências e atividades realizadas no âmbito da extensão universitária através do Programa Laboratório de Gestão: Práticas em Empreendedorismo, Inovação e Sustentabilidade (LAGEIS-ADM). O programa visa atender às demandas da comunidade empresarial, tanto do setor público quanto do privado, bem como de potenciais empreendedores, fornecendo apoio na gestão de negócios, formação profissional, empregabilidade, inclusão social e geração de renda. Com base na legislação educacional brasileira, que estabelece a promoção da extensão como uma das finalidades das universidades, o LAGEIS-ADM se propõe a difundir conhecimento e benefícios gerados na instituição por meio de ações de extensão voltadas para a comunidade, contribuindo assim para o desenvolvimento local.
CONTROLE ESTOQUE EM EMPRESAS FAMILIARES: UMA PESQUISA DE LEVANTAMENTO NA CIDADE DE IMBAÚ-PR
Authors: Brazi Ribeiro Rossano , Moletta Juliana
Published: March 2024

As empresas precisam se adequar aos novos tempos e para garantir resultados é essencial que universidades, empresas e administradores estabeleçam uma relação imperecível e benéfica, a ponto de garantir resultados para os pequenos empresários para auxiliar na gestão das pequenas empresas familiares. Assim sendo, este trabalho tem como objetivo analisar a gestão de estoques e materiais em pequenas empresas familiares na cidade de Imbaú - PR., em especial, empresas de vestuários, calçados e artigos em geral, localizados na região central da cidade. A metodologia utilizada na pesquisa caracterizou-se como uma pesquisa exploratória, quanto aos fins, e de levantamento em relação aos objetivos técnicos, bem como os meios de investigação. Para a obtenção dos dados necessários para alcançar os objetivos do presente trabalho, foi aplicado um questionário para pesquisa de campo, utilizando da ferramenta Google Forms. Por meio da pesquisa realizada, notou-se que 57,9% dos empreendedores utilizam sistema para realizar o controle dos estoques e 26,3% não fazem controle algum. Foi possível identificar também que 80% dos empreendedores efetuam ações, como promoções, para reduzir os estoques que estão com a demanda baixa. Foi possível orientar gestores por meio da indicação de planilhas ou sistemas ERPs para auxiliá-los na gestão de estoques.
The role of talent retention as an employee motivator in the fast-moving consumer goods industry
Authors:   , Manowah Kavetha
Published: March 2024

The fast-moving consumer goods (FMCG) industry is a highly competitive and progressive sector where companies must attract and retain the best skills to remain relevant and successful. In this ever-changing, modernizing world, organizations are compelled to keep up with trends on how to manage employees, motivate, and retain them. This study aimed to investigate the extent to which talent retention strategies can be contributory factors to employee motivation, which positively influences the employee’s intention to stay with the organization. This study explored various talent retention strategies and tested their impact on employee motivation, using a series of analytical tests. An exploratory approach was used with a non-probability sampling design, specifically judgmental sampling was used as respondents chosen for this study were based on specific characteristics. Since the research design of this study is quantitative, a structured questionnaire was sent to 130 respondents, of which 124 respondents successfully completed the questionnaire. The results showed that there were gender inequalities in the workplace. Furthermore, employee participation had an influence on employee motivation. Compensation and benefits, training and development, and work-life balance did not have an influence on employee motivation, amongst other interesting findings. These findings are relevant to the FMCG industry and contribute to the existing framework of knowledge.
Средневзвешенная категория состояния деревьев как критерий ослабления древостоя
Authors:   Mytischi branch of MSTU. N. Uh. Bauman, Trofimov Vladimir , Trofimova Olga ,   Moscow Regional State Pedagogical University
Published: March 2024

The issue of using a weighted average assessment of the health of trees condition Kср as a criterion for the sanitary condition of a stand on the example of spruce and birch forests. Based on the growth tables, Kср developed for five categories of tree health status with differentiation of results by age groups and assessment methods (by stock volume or by number of trees). It showed that exceeding Kср of 1.5 is not a sufficient criterion for the unsatisfactory sanitary condition of the stand. For a stand with natural thinning by age the estimations Kср are increase from Ia to V quality of locality and are decrease with age groups. The estimates Kср by number of trees may exceed similar estimates by stock volume by 0.1-0.3 points. For a young and middle age of healthy stands with natural thinning, the evaluations Kср usually exceed 1.5 points. Proposed the criteria Kср with the differentiation on age groups and assessment methods. As rough criterion of unsatisfactory sanitary state it is possible to accept excess of average weighted of estimations (on a stock volume/on number of trees): Kср :in middle-aged stands - 1,7/2,0, in ripening stand - 1,5/1,7, in ripe and maturity and old-growth stand 1,2/1,4. Keywords: CONDITION OF FOREST STAND, WEIGHTED AVERAGE ESTIMATE
Development of Freelancer Market Software System Based on JavaScript
Authors: Tanvir Aminur Rahman , Xingfang Jiang
Published: March 2024

With the continuous development of the Internet, people are looking forward to establishing a network of contacts between employees and employers in the service industry through the Internet [1-2]. To this end, the TaskDigger online platform has been designed and developed. The front end includes Express JavaScript, JavaScript, JQuery, CSS3, Bootstrap, and a few NPM packages. The back end includes Node JavaScript, EJB, and more NPM packages for back-end development. It runs on the V8 engine, Execute JavaScript code outside of a web browser. Visitors can search for performance services or recruitment information at any time, publish assignments, and both buyers and sellers can communicate and sign contracts at any time. This platform has maintainability, portability, repeatability, flexibility, safety, and reliability, providing a helping hand for the gig economy.
Design, Development and Testing of a Hospital Website
Authors: das Choyon , Xingfang Jiang
Published: March 2024

With the deepening of Internet applications, patients expect hospitals to make appointments, communicate information and obtain reports anytime and anywhere through websites. To solve this problem, we have designed and developed a “Hospital” website, which uses iterative and incremental process models and “natural observation method”, and uses React, Node, JavaScript, MongoDB and other Web tools for front-end and back-end development, including hospital dynamic description, The website achieves a 24-hour appointment and communication channel between patients and doctors, with a concise and safe operation interface through repeated testing, and real-time access to test reports. This “Hospital” website can be promoted and used in large traditional Chinese medicine hospitals.
Design and Production Skills of Modern Physics Experiment Report Website
Authors: Rinku Ali Md , Xingfang Jiang , Tanvir Aminur Rahman , Das Choyon
Published: March 2024

In view of the large number of modern physics experiment reports, the situation is complex, and it is inconvenient to browse, specifically, there are 35 students in class 1, 42 students in class 2, and students do all 12 experiments, but one student chooses to do 9 experiments, and the normal modern physics experiment report has 8 pages, and the pictures provided by the students are some big and some are small; Some are in .jpg format, some are in .png format; some figures are skewed. To this end, it is proposed to make a modern physics experiment report website based on Dreamweaver that can quickly browse all students, and the problem that needs to be solved is that the pictures are named according to the student number, the experimental serial number, and the page serial number, the size of the picture is unified, and the crooked pictures are taken for correction, and the top, left, and main three frame websites are designed to be easy to browse, and the website data produced is large, but neat and easy to browse.
Challenges in Management and Liver Abscess in General Hospitals with Limited Facilities: A Case Report
Authors: Gunawan Agustinus Alfred , Effendy Rambu Farah
Published: March 2024

Introduction: Liver abscess is a mass containing pus in the liver which can develop into an intra-abdominal infection. Poor environment and sanitation, as well as difficulty in accessing clean water, are risk factors for liver abscesses. We report the findings of patients with liver abscesses, identification, and treatment from Waikabubak General Hospital. Case Presentation: Male, 34 years old, came to hospital with symptoms such as right upper abdominal pain since 1 week ago, accompanied by fever and nausea, vomiting. Two weeks previously the patient was said to have loose stools with a frequency of 3-4x/day. The patient is a farmer, drinks boiled tap water every day, and lives in a place with poor sanitation. Physical examination showed icteric sclera, liver palpable 3 fingers below the costal arch, and tenderness (+). Laboratories showed leukocytosis with a predominance of neutrophils and elevated liver enzymes. Ultrasound results showed a mass in the right lobe measuring +/- 4.2 x 4.16cm. The patient was treated with cefotaxime and metronidazole, as well as symptomatic management. Over a week showed clinical improvement, as well as a decrease in the size of the abscess. Discussion: The diagnosis is made from anamnesis, physical examination, and limited support. Determining the cause of an abscess is a challenge, the results of leukocytosis with a predominance of neutrophils are a reference in management. Environment and lifestyle are risk factors for liver abscess. Conclusion: Immediate and appropriate treatment can reduce the rate of complications. Government participation is needed to improve the quality of health and improve the quality of life of the people of West Sumba.
High Levels of Monocyte Chemoattractant Protein-1 Plasma Are A Risk Factor for Neurocognitive Disorders in Human Immunodeficiency Virus Infection with Antiretroviral Therapy
Authors: Yogi Prima , Utama I Made Susila
Published: March 2024

Background: HIV-associated neurocognitive disorder (HAND) is a neurocognitive dysfunction caused by HIV infection. The prevalence of neurocognitive disorders of HIV in Indonesia is about 51%. Despite receiving antiretroviral therapy, HAND is still a common complication that causes morbidity in people with HIV. One of the foundations of HAND pathogenesis is inflammation. Infection of macrophages/microglia and astrocytes leads to excessive production of viral gene products and chemokines, one of them is Monocyte chemoattractant protein 1 (MCP-1). The purpose of this study was to determine plasma MCP-1 levels that increase the risk of neurocognitive disorders in HIV infection with antiretroviral therapy. Methods: This matched case-control study involved 76 subjects with HIV, 38 subjects with neurocognitive disorders, and 38 subjects without neurocognitive disorders. Cognitive status was reviewed based on MoCA-Ina examination criteria. Plasma MCP-1 levels were measured by enzyme-linked immunosorbent assay (ELISA). Results: Of the 76 subjects, the mean age of the case group was 42.08 ± 9.44 years and the control group was 42.16± 8.90 years. The cut point value based on the ROC curve of the plasma MCP-1 level was 82.14 pg/mL. It had an 86.8% sensitivity and 52.6% specificity for the occurrence of neurocognitive disorders in HIV. The risk of neurocognitive disorders in HIV was found in MCP-1 plasma ≥ 82.14 pg/mL (OR 7.33, p < 0.001, CI 95% = 2.35-22.83). Based on multivariate analysis, MCP-1 levels were independently associated with the incidence of neurocognitive disorders in HIV (AOR 11.01, CI 95% = 2.75-44.01, p=0.001). Conclusion: This study showed that high plasma MCP-1 levels were an event risk factor for neurocognitive disorders in HIV with antiretroviral therapy.
Partnership of University Institutions with Industries and Graduates’ Employability in Cameroon: Case of Graduates of Technical and Professional Schools of the University of Ngaoundéré
Authors: Ngesi Ngang Josephine Lum , André Wamba , Kongnyuy Patrick , Ange Maïn-ndeiang Laoungang
Published: March 2024

Context: Graduate employability remains a global interest in this 21st century as workplace demands and economic sustainability are growing, changing, and driving new competencies and needs as well as the need for an innovative, flexible, and motivated workplace. The quality of university graduates is not only crucial to individual productivity but also to national productivity, economic growth, and development. This quality could be enhanced by effective collaboration between institutions of the university and the industry. Therefore, this study examines the influence of the quality of partnerships between university institutions and industries on the employability of graduates from technical and professional schools of the University of Ngaoundere. Methods: A cross-sectional study using an online questionnaire was conducted amongst graduates from the University of Ngaoundere recruited through snowball and purposive sampling. The data were analyzed by SPSS Software, Version 20, using descriptive statistics and simple linear regression. Results: Findings revealed that the quality of the partnership between university institutions and industries strongly and significantly influences graduates’ employability (R2 =0.505, β=0.711, p<0.001). Conclusion: Therefore, the study recommends that effective educational policy and strategy should be adopted to improve graduates’ employability by focusing on improving collaboration and cooperation between university institutions and industries.
Administration of Arabika Coffee Leaf Extract (Coffea Arabica) Reduces Tumor Necrosis Factor Alpha (TNF-α) and Sunburn Cell Levels in Male Wistar Rats (Rattus norvegicus) Exposed to Ultraviolet-B Rays
Authors: Dewi Eka Diah Frisilia , Praharsini I.G.A.A , Damayanti Putu Ayu Asri , Linawati Ni Made , Dinata I Made Krisna
Published: March 2024

Background: Ultraviolet (UV) radiation has acute and chronic impacts on the skin. However, UVB exposure can be prevented with available natural ingredients, especially those containing antioxidants. One of the natural ingredients that contains active compounds as antioxidants is arabica coffee leaves, which contain flavonoids that have antioxidant effects. Methods: This study was an experimental research with a post-test-only control group design, using 30 male Wistar rats (Rattus norvegicus) which were divided into 5 groups; the control group (P0), treatment group 1 (P1) were given placebo, while group 2 (P2), group 3 (P3) and group 4 (P4) was given UVB rays and given ethanol extract cream from Arabica coffee leaves at a dose of 2,5%, 5%, and 10% respectively. Results: The average TNF- α levels in group P0, P1, P2, P3, and P4 were 97,88±1,19 ng/mL, 162,41±1,87 ng/mL, 138,04±1,03 g/mL, 124,71±2,65 ng/mL and 107,18±1,52 ng/mL. The average sunburn cells in P0, P1, P2, P3, and P4 were 4,0±0,13, 4,07±0,27, 2,60±0,25, 1,67±0,15 and 1,33±0,12 per field view. The administration of 10% Arabica coffee leaf extract cream was the most effective in reducing TNF-α levels by 34.01% (p<0.001) and has the lowest sunburn cells per field view (1,33±0,12 cell/field view; p < 0,001). Conclusion: Administration of ethanol extract cream from Arabica coffee leaves (Coffea arabica) can reduce TNF-α levels and the number of sunburn cells in the skin of male Wistar rats (Rattus norvegicus) exposed to UVB radiation.
Implementation of the Clean School: Challenges and Prospects in the Far North Region’s Secondary Schools in Cameroon
Authors: Utagah Eneng Lilian , Ngwa Peter
Published: March 2024

The implementation of the clean schools remains a global interest in 21st-century secondary schools. To make the world a more sustainable and better place to live in, humanity needs to be able to generate solutions to increasingly complex, and ever-growing challenges in the secondary school setting. Secondary schools encounter day-after-day violence linked happenings students. Violence has caused secondary school unrest, refusal to undertake various activities, sitting in and at other instances, complete damage of institutional assets, and in other instances, death. Other reasons that led to drug abuse included social pressure from the media, frustrations due to poverty, low self-esteem, depression, anxiety, need to relax and overcome boredom, among others. This research sought to develop prevention and intervention strategies for curbing violence in public secondary schools in the Far North Region of Cameroon. The objective of the study is to find out various ways and means used by secondary school management to implement the clean school concept in public secondary schools. A purposive sampling technique was used to select 10 participants both inspectors, teachers, and principals in public secondary schools. The study indicated that the effects of drug abuse include addiction, violence, and high-risk sexual behavior. To minimize and eliminate violence the school to educate, guide, and counsel the students, and school management should reward staff that promote the clean school implementation. The study recommended that to implement clean schools every category such as parents, teachers, and administrators should be concerned and keep the focus on the things that bring honor and success to them and the school. All staff in the school should give constant and continuous guidance to students.
FORMULASI SEDIAAN HAND SANITIZER GEL DARI EKSTRAK ETANOL GOJI BERRY (Lycium barbarum L.)
Authors: Chandra Devina , Suryani Monica , Tandiono Steven , Wahyuni Sri
Published: March 2024

Hand sanitizer merupakan produk pembersih tangan yang banyak digunakan masyarakat, karena cara pemakaiannya yang praktis. Penelitian inimencari alternatif untuk mengurangi penggunaan alkohol dengan cara memakai bahan alam yang lebih aman seperti ekstrak etanol goji berry (Lycium barbarum L.), karena goji berry memiliki kandungan flavonoid yang sangat tinggi sehingga dapat membunuh dan menghambat pertumbuhan  kuman. Tujuaan penelitian ini untuk mengetahui ekstrak etanol goji berry dapat dijadikan sebagai sediaan hand sanitizer gel yang memenuhi mutu fitokimia. Metode yang dilakukandalam penelitiaan ini meliputi, pembuatan ekstrak etanol goji berry dengan etanol 96%, yang selanjutnya diformulasikan menjadi sediaan hand sanitizer gel dengan konsentrasi 5%, 10%, 15% dan 20%, dan dilakukan evaluasi mutu sediaan tersebut. Hasil dari pengujiaan evaluasi yang dilakukan terhadap kelima sediaan, yaitu uji organoleptis menunjukkan semakin tinggi konsentrasinya maka warna sediaan akan semakin pekat, bentuk semi padat dan aromanya berbau khas. Uji homogenitas ditunjukkan dengan tidak adanya butiran kasar pada sediaan. Uji daya sebar untuk F0 (6,23), F1(6,33), F2 (6,16), F3 (6,33), dan F4 (6,53) cm. Uji pH sediaan yang diperoleh F0 (6,5), F1 (5,9), F2 (5,1), F3 (4,2), dan F4 (4,0). Uji viskositas menunjukkan sediaan F0 (10.400), F1 (6.000), F2 (7.600), F3 (5.600), dan F4 (4.000) cPs, semua sediaan memenuhi persyaratan sesuai SNI. Uji iritasi menunjukkan semua sediaan memberikan hasil negative. Warna, bau, dan bentuk sediaan gel yang lebih disukai venalis adalah F2 dengan konsentrasi 10%, tetapi sediaan yang memenuhi standar untuk sediaan hand sanitizer gel adalah F1 dengan konsentrasi 5%. Dari hasil tersebut dapat disimpulkan bahwa ekstrak etanol goji berry dapat diformulasikan sebagai hand sanitizer gel dan memenuhi persyaratan evaluasi dan mutu fitokimia.
THE ROLE OF SELF-CONFIDENCE IN MEDIATING INFLUENCERS, MATERIALISM, AND THE SOCIAL ENVIRONMENT ON ONLINE IMPULSE BUYING IN INDONESIA
Authors:   Universitas Pancasakti Tegal, Indonesia, Prihadi Deddy , Harira Irawan Bei ,   Universitas Pancasakti Tegal, Indonesia, Waskita Jaka ,   Universitas Pancasakti Tegal, Indonesia, Utami Yuni ,   Universitas Pancasakti Tegal, Indonesia
Published: March 2024

Impulse buying behavior will open up opportunities for business actors, where business actors have the opportunity to fulfill consumer desires by providing a wide choice of products or services and encouraging consumer impulse purchases. Business actors need to know the determinants of consumer impulse buying. This research aims to determine the determinants of online impulse buying as seen from influencers, materialism, and the social environment with self- confidence as a mediator, so that businessmen can implement appropriate business strategies to encourage consumers impulse buying behavior. The data collection technique used an online survey with the Google Forms survey platform. This data was then distributed via social media such as WhatsApp (personal and group contacts), Instagram, and X (Twitter). The questionnaire in the research was given to the entire population, and they were consumers who shop online. The data analysis used in hypothesis testing was Structural Equation Modeling (SEM) with SmartPLS. This study was successful in determining the effects of materialism, social environment, and self- confidence on online impulse buying, but it was unable to confirm the influence of influencers on online impulse buying. Data from studies revealed that self-confidence could mediate the influence of influencers and the social environment, but it failed to demonstrate the importance of self- confidence in moderating the influence of materialism on online impulse purchases.
In–Situ Measurements of the Performance of ermosyphon Solar Water Heating Systems in Libya
Authors: Abdunnabi Mohamed , Loveday D.
Published: March 2024

This paper reports on a project carried out by the Centre for Solar Energy Research and Studies (CSERS) to familiarise Libyan people with solar water heating technologies. Around 100 solar water heaters have been installed in the domestic sector and selected systems were equipped with monitoring instruments required to evaluate thermal performance. The paper presents the results of data collected over a one year period from a system installed in a family residence situated in a village located 90 km south of Tripoli(Libyan capital). The results showed that the system solar fraction was 55.8% of the average amount of daily hot water withdrawn (144 litres) at an average withdrawal temperature of 46.6 °C. T e total energy withdrawn during the whole year was 1557 kWh. It is concluded that such a system is not adequate in terms of cost-effectiveness for the current installed situation. It is recommended that the annual solar fraction for any solar water heating system should be over 70% in order to achieve cost-effectiveness and to help widespread take-up of this technology.
Unlawful acts against the rights of nature and environmental impact
Authors: Herrera Acosta Carlos Ernesto , Albán Jácome Doménica Lizbeth  , Machado Ashqui Ana Lucia , Aldaz Arevalo Gianella Liseth
Published: March 2024

The evolution of mankind, driven by developments in society, science, and technology, has had a significant impact on Mother Earth or nature, resulting in serious effects on the environment, ecosystems, and biodiversity. This research critically analyses illicit acts that violate the rights of nature and assesses their environmental impact. To achieve this, we employed an approach that incorporates inductive, dogmatic, historical-logical, and descriptive legal methods through a non-experimental design. The research results show a concerning lack of respect for the rights of nature in Ecuador. Furthermore, the inadequate control of illegal acts, including the endorsement of deforestation and the illegal and irresponsible extraction of natural resources, are causing a substantial negative impact on the environment, ecosystems, flora, and fauna.
O IMPACTO DA TECNOLOGIA BIM NA OTIMIZAÇÃO DO PLANEJAMENTO E GESTÃO DE PROJETOS DE CONSTRUÇÃO
Authors: Jiquiriçá Maria Clara Rodrigues
Published: March 2024

Esse artigo buscou se concentrar na análise da tecnologia BIM (Building Information Modeling), com o intuito de apresentá-la como um meio alternativo para a melhoria no tempo, eficiência e qualidade de um projeto. Com esse propósito, é primordial que seja realizada uma análise comparativa entre o tempo de elaboração de um projeto residencial de pequeno porte, utilizando inicialmente o Revit e, em seguida, o AutoCAD e o Excel. Nesse contexto, foi realizado um levantamento bibliográfico dos conceitos fundamentais de planejamento e da tecnologia BIM, além de um breve histórico do modelo. A pesquisa foi seguida pela metodologia e pela análise de resultados, onde se coletou dados para uma comparação do tempo de elaboração entre os dois métodos já citados, sendo demonstrado por meio de um gráfico. A partir disso, observa-se que o Revit, com sua aplicação da tecnologia BIM, apresenta vantagens relacionadas ao tempo dedicado ao planejamento de projetos, o que incute a constatação de que, a adoção de programas que utilizam a tecnologia BIM otimiza o tempo de planejamento e a gestão na área da construção civil. No entanto, inicialmente, o tempo de aprendizado do software pode ser considerado um desafio.