bluuebunny/crossref_metadata_2025 huggingface dataset:
Symmetrical interdigital hyperkeratosis of the hands: a new case.
Authors: Patrizi A , Neri I , Di Lernia V , Varotti C
Published: July 2023

Congenital symmetrical interdigital hyperkeratosis is a rare disorder described by Frei in 1923, characterized by localized hyperkeratosis of the interdigital spaces of the hands and feet. The authors report the case of a 7/year/old girl affected by this condition. The skin hyperkeratotic lesions appeared localized exclusively to the interdigital spaces of the hands. Histologic examination showed orthokeratotic hyperkeratosis, hypergranulosis and acanthosis. Keratolytics failed to improve the clinical picture.
Autotransplantation in vitiligo: treatment with epidermal grafts and cultured melanocytes.
Authors: Zachariae H , Zachariae C , Deleuran B , Kristensen P
Published: July 2023

Previous studies have shown the usefulness of autologous grafts carrying melanocytes for treatment of vitiligo. In our study repigmentation was obtained in three patients using epidermal sheets from suction blisters. The repigmentation was found stable in follow/ups from one to three years. The most homogenic repigmentation, however, was found in a patient treated by grafting autologous melanocytes applied to the dermabraded areas of vitiligo by collagen film.
Repigmentation of vitiligo by transplantation of cultured autologous melanocytes.
Authors: Olsson M J , Juhlin L
Published: July 2023

Autologous cultured melanocytes were transplanted to superficially dermabraded vitiligo areas in ten patients. Good cosmetic results were obtained in nine patients with stable vitiligo, but in one patient with new, increasing areas of vitiligo no pigmentation was seen 3 months after transplantation.
Immunohistochemical localization of basic fibroblast growth factor in skin diseases.
Authors: Yaguchi H , Tsuboi R , Ueki R , Ogawa H
Published: July 2023

The basic fibroblast growth factor (bFGF) is an angiogenic factor and also a mitogen for epidermal keratinocytes. In order to investigate the role of bFGF in human skin we examined the distribution of bFGF immunoreactivity in normal and diseased human skin. Antigen expression was demonstrated by direct immunofluorescence staining of cryostat sections with a polyclonal anti/bFGF antibody. In normal human skin, bFGF/like immunoreactivities were observed in the basal cells, while in the case of psoriasis, positive immunoreactivities were observed in the basal cells and several supra/basal layers at rete ridges. Seborrheic keratosis and basal cell epithelioma showed diffuse immunoreactivities in the basaloid cells of the tumor. Concurrently, benign nevus cell nevus, capillary hemangioma, squamous cell carcinoma and malignant melanoma displayed negative immunoreactivities. These results suggest that bFGF is important for basal or basaloid cell proliferation.
Histamine effect on human cutaneous blood flow: regional variations.
Authors: Tur E , Aviram G , Zeltser D , Brenner S , Maibach H I
Published: July 2023

Different reactivities of small blood vessels to the histamine released by exogenous and endogenous substances may play a role in the regional variations of the elicited cutaneous response. To study the regional dependence of cutaneous blood flow in response to histamine, the compound was administered intradermally (prick introduction), thereby bypassing the spatially dependent penetration process. The induced response was quantified with cutaneous blood flow measurements utilizing laser Doppler flowmetry. Extent of response and time parameters were compared. Three anatomical sites, the back, volar side of the forearm, and ankle, were studied on 20 volunteers (10 men and 10 women, age 24-34). For comparison, topical administration was also performed. Significant differences in the measured responses at the three sites were observed: the increase of the cutaneous blood flow on the back was greater than the forearm (p < 0.01 prick test, p < 0.05 topical application), and that of both sites was greater than the ankle (p < 0.01 prick test, p < 0.05 topical application). There were no significant differences among the different sites in time parameters and no gender variations. As expected, the time required to reach maximum response was shorter for the intradermal method as compared to the topical application on the back (p < 0.001) and forearm (p < 0.05). On the other hand, the time required to decrease to 50% of maximum response was not different for the intradermal and topical methods of histamine application. These blood vessel response observations may provide initial insight into inherent functional differences influencing cutaneous manifestations of endogenous and exogenous diseases.
Weekly treatment of psoriasis with a hydrocolloid dressing in combination with triamcinolone acetonide. A controlled comparative study.
Authors: Van de Kerkhof P C , Chang A , Van der Walle H B , Van Vlijmen-Willems I , Boezeman J B , Huigen-Tijdink R
Published: July 2023

In a within subject comparison, the efficacy and the tolerability of topical treatment with triamcinolone acetonide under a hydrocolloid dressing were compared with triamcinolone acetonide monotherapy, monotherapy with hydrocolloid dressing and triamcinolone acetonide under plastic occlusion. The clinical efficacy of hydrocolloid dressing as a monotherapy and the pronounced clinical efficacy of this occlusive in combination with triamcinolone acetonide were confirmed. Comparing the hydrocolloid dressing (Duoderm E) and the plastic semi-occlusive (Opsite IV 3000), we concluded that the tolerability of both approaches was similar. However, Duoderm E in conjunction with triamcinolone acetonide was highly effective, whereas Opsite IV 3000 in combination with this steroid only had an inconspicuous antipsoriatic potential.
Immunohistochemical localization of p53 protein in malignant hemangioendothelioma.
Authors: Inohara S
Published: July 2023

The immunohistochemical localization of p53 protein was examined in skin tissue sections, including normal vascular endothelial cells and the skin tissue sections from lesions of granuloma telangiectaticum with proliferation of vascular endothelial cells and malignant hemangioendothelioma, a malignant tumor originated from vascular endothelial cells. It was found that p53 protein was positive in 2 out of 4 cases of malignant hemangioendothelioma. Thus, immunohistochemical detection of p53 protein proved useful in the diagnosis of malignant hemangioendothelioma.
Immunosuppression in patients with syphilis and problems of human immunodeficiency virus infection.
Authors: Tseraidi N F
Published: July 2023

An investigation of the induced suppression and cytotoxicity of T lymphocytes, carried out in 57 patients with different forms of syphilis, has made it possible to find some reasons for the depression of cell-mediated immunity (CMI) in patients with early syphilis. The analysis of the immunoreaction of patients with different forms of syphilis clarifies the influence of the human immunodeficiency virus (HIV) on the dynamics and formation of syphilis manifestations.
A DNA-flow cytometric analysis of trichilemmal carcinoma, proliferating trichilemmal cyst and trichilemmal cyst.
Authors: Hashimoto Y , Matsuo S , Iizuka H
Published: July 2023

DNA-flow cytometric analyses were performed on paraffin-embedded sections of trichilemmal carcinoma, proliferating trichilemmal cyst, and trichilemmal cyst. Nine out of 10 cases of trichilemmal carcinoma and 2 out of 5 cases of proliferating trichilemmal cyst showed aneuploidy. No aneuploidy was detected in 6 cases of benign trichilemmal cyst. The proliferating index (percentage of cells that exceeded the diploid peak (G0/G1) plus 4 standard deviations) of trichilemmal carcinoma, proliferating trichilemmal cyst, and trichilemmal cysts was 43.5 +/- 3.8%, 32.5 +/- 7.5%, and 23.1 +/- 2.0%, respectively. In one out of the 6 cases of trichilemmal carcinoma that were large enough for us to investigate regional differences, DNA ploidy heterogeneity was detected. The incidence of aneuploidy of trichilemmal carcinoma was significantly higher than that of squamous cell carcinoma (14%), previously described by us using the same method.
Toxic epidermal necrolysis and erythema multiforme following therapy with terbinafine.
Authors: Carstens J , Wendelboe P , Søgaard H , Thestrup-Pedersen K
Published: July 2023

We report two cases with severe skin reactions following oral terbinafine (Lamisil) therapy. The first case was a 49-year-old woman with onychomycosis of the toe nails. She had suffered from diabetes for 3 years, but it was well controlled on insulin. Five days after start of terbinafine 250 mg once daily she developed erythema. The treatment was continued for 2 days, but the skin eruption progressed, and a clinical diagnosis of toxic epidermal necrolysis was confirmed histologically. The second case was a 51-year-old woman with dermatomycosis on the right foot. She developed a papular eruption in the second week after taking terbinafine 250 mg once daily. Despite this eruption she continued treatment for 6 days. Generalized erythema multiforme developed in the following days. Terbinafine is a recently introduced efficacious fungicidal drug. This is the first report of toxic epidermal necrolysis following terbinafine.
Polymerase chain reaction for monitoring human papillomavirus contamination of medical personnel during treatment of genital warts with CO2 laser and electrocoagulation.
Authors: Bergbrant I M , Samuelsson L , Olofsson S , Jonassen F , Ricksten A
Published: July 2023

Genital warts and intraepithelial neoplasia caused by infection with human papillomavirus are usually treated with CO2 laser or electrocoagulation. In this study, contamination of personnel and operating theatres with human papillomavirus DNA during treatment sessions was investigated. Samples were taken from the nostrils, nasolabial folds and conjunctiva of the operating physician before and after operating sessions and from Petri dishes left open in the operating theatres. Human papillomavirus DNA was demonstrated by the polymerase chain reaction technique. The results show that there is a risk of contamination of the operator by human papillomavirus DNA, detectable with the polymerase chain reaction technique, during both CO2 laser and electrocoagulation treatment.
Efficacy and safety of the 20-epi-vitamin D3 analogue KH 1060 in the topical therapy of psoriasis: results of a dose-ranging study.
Authors: Kragballe K , Dam T N , Hansen E R , Baadsgaard O , Grønhøj Larsen F , Søndergaard J , Axelsen M B
Published: July 2023

KH 1060 is a 20-epi-vitamin D3 analogue, structurally related to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). In vitro, KH 1060 is much more potent than 1,25(OH)2D3 in regulating cell growth and T lymphocyte mediated immune responses, despite a similar calcemic activity in vivo. Therefore, KH 1060 is of potential interest in the treatment of psoriasis and other diseases characterized by accelerated cell growth and T lymphocyte activation. In a multicenter, prospective, randomized, double-blind, vehicle-controlled right/left comparative study, patients with plaque-type psoriasis vulgaris were randomly assigned to one of the following treatment groups: (I) KH 1060 ointment 0.2 microgram/g versus placebo ointment, (II) KH 1060 ointment 0.2 microgram/g versus KH 1060 ointment 0.04 microgram/g, and (III) KH 1060 ointment 0.2 microgram/g versus KH 1060 ointment 1 microgram/g. All treatments were given twice daily for 6 weeks. Sixty-four of the 70 randomized patients completed the study. At the end of treatment, no difference was demonstrated between KH 1060 0.04 microgram/g and vehicle, whereas significantly increasing improvement was found for the doses KH 1060 0.2 microgram/g and KH 1060 1 microgram/g. According to the investigator's overall assessments at the end of treatment, KH 1060 1.0 microgram/g and KH 1060 0.2 microgram/g produced a marked or moderate improvement in most patients. Mild lesional irritation was observed after treatment with KH 1060 as well as with placebo. One patient was withdrawn because of an eczematous reaction, where KH 1060 1.0 microgram/g was applied.(ABSTRACT TRUNCATED AT 250 WORDS)
Cutaneous vasculitis in psoriasis.
Authors: Wong S S , Marks R
Published: July 2023

Cutaneous vasculitis has been reported as a complication of pustular psoriasis but not of plaque type psoriasis. In the past 5 years we have observed 3 patients who in the course of their psoriasis developed cutaneous vasculitis. Two of these patients also had severe psoriatic arthropathy and were on etretinate during the onset of vasculitis. However, there was no deterioration or recurrence of vasculitis whilst the patients were maintained on the drug. The third patient with vasculitis had not received retinoids. No obvious causes of vasculitis were found in the 3 patients and the rash resolved spontaneously without any systemic complications though surgical amputation was necessary in one case. None of the cases required immunosuppressive therapy and the skin lesions mostly resolved spontaneously. The mechanisms that triggered off vasculitis in our patients are unknown but are likely to be immune-mediated.
Minimum 20-year follow-up of a press-fit acetabular cup in cementless total hip replacement in young patients
Authors: Lunz Andre , Von Falkenhayn Moritz , Jaeger Sebastian , Reiner Tobias , Merle Christian , Streit Marcus R , Renkawitz Tobias , Innmann Moritz M
Published: July 2023

Purpose: We aimed to determine the minimum 20-year survival rates of a cementless press-fit cup in young patients.Patients and methods: This is a retrospective, single-center, multi-surgeon cohort study investigating the minimum 20-year clinical and radiological outcome of the first 121 consecutive total hip replacements (THRs) using a cementless, press-fit cup (Allofit, Zimmer, Warsaw, IN, USA) performed between 1999 and 2001. 28-mm metal-on-metal (MoM) and ceramic-on-conventionally not highly crosslinked polyethylene (CoP) bearings were used in 71% and 28%, respectively. Median patient age at surgery was 52 (range 21–60) years. Kaplan–Meier survival analysis was conducted for different endpoints.Results: The 22-year survival rate for the endpoint aseptic cup or inlay revision was 94% (95% confidence interval [CI] 87–96) and 99% (CI 94–100) for aseptic cup loosening. 20 patients (21 THRs; 17%) had died and 5 (5 THRs; 4%) were lost to follow-up. No THR showed evidence of radiographic cup loosening. Osteolysis was observed in 40% of THRs with MoM and 77% with CoP bearings. 88% of THRs with CoP bearings showed significant polyethylene wear.Conclusion: The investigated cementless press-fit cup, which is still in clinical use today, showed excellent long-term survival rates in patients under the age of 60 years at surgery. However, osteolysis due to polyethylene and metal wear was frequently observed and is a matter of concern in the third decade after surgery.
The Challenges of Digital Transformation of Communication Technologies: The case of VAR and Human Errors in the English Premier League 2022 - 2023 season
Authors:   Mohammed V University, Rabat, Maroc, Sogheir Mehdi , Larhrissi Nadia ,   Mohammed V University, Rabat, Maroc
Published: July 2023

The implementation of Video Assistant Referee (VAR) technology in football has brought about significant changes to the game, particularly in terms of communication and decision-making. However, despite its intended benefits, human errors by VAR officials have been a recurring problem that has affected the accuracy and effectiveness of the system. This study aims to examine the challenges of digital transformation of communication technologies, specifically the case of VAR and human errors in the English Premier League (EPL) during the 2022/2023 season. Using a qualitative content analysis approach, two instances of VAR human errors were analysed to identify the type of errors, the player/team affected, and the consequences of the errors. The findings suggest that VAR human errors can have significant implications for the game, affecting the outcome and fairness of matches. The study highlights the importance of addressing human errors in VAR implementation in order to improve the accuracy and effectiveness of the system and maintain the integrity of the game.
Tradisi Semedi di Makam Raja-Raja Masjid Gedhe Mataram Kotagede Yogyakarta Tinjauan Filsafat : Ontologi
Authors: Yulita Jumada Barqah  , Fauzi Ahmad
Published: July 2023

Penelitian ini dilakukan untuk mengetahui tradisi masyarakat Jawa, khususnya di Yogyakarta, terkait kegiatan semedi di depan makam raja-raja mataram islam untuk mendapatkan wasilah atau berkat. Tradisi ini dilihat dari aspek ritualistik yang dikorelasikan dengan filsafat ontologi. Dasar teori yang digunakan adalah teori filsafat ontologi dan teori mistik. Dalam teori ini, ontologi lebih melihat semedi dalam kacamata metafisika dan mistik sendiri dilihat dari aspek kebatinan. Pendekatan dalam penelitian ini adalah deskriptif kualitatif. Metode yang digunakan dalam penelitian ini adalah menggabungkan metode etnografi yaitu peneliti melakukan studi lapangan terkait sebuah budaya dengan analisis observasi dan wawancara. Informan dari penelitian ini adalah abdi dalem penjaga makam dan penziarah yang melakukan ritual semedi. Hasil dari penelitian ini menunjukkan bahwa kegiatan manusia mencari sebuah realitas kebenaran yang menurut keyakinannya ada meski dalam kenyataannya dianggap abstrak atau non empiris tetap bisa diterima oleh akal rasional manusia dan representatif dari kajian teori mistik dapat menjawab sebuah tradisi di suatu kelompok masyarakat yang mampu menafsirkan suatu pengalaman spiritual dengan ilmu kebatinan. Simpulan dari artikel ini filsafat ilmu ontologi bisa menjadi jembatan untuk menjelaskan sebuah realitas yang terjadi di masyarakat Jawa khususnya Yogyakarta terkait tradisi budaya non empiris dalam kacamata dimensi ritualistik dan metafisika.

Kata Kunci: Semedi., Mistik., Ontologi., Metafisika
The Harmony Level Among Lecturers of The Teacher Education Institute in Peninsular Malaysia
Authors: Mutalib Kartini Abdul , Aris Mazlan , Yusof Masitah Mohammad , Rahim Ahamad , Yusoff Suhaili Mohd
Published: July 2023

Harmony and enjoyment at workplace have a positive influence on commitment, work productivity and loyalty to the organization. Therefore, this study aims to identify the level of harmony that consists of the dimensions of self-motivation, external motivation, physical environment, psychosocial and personal health among IPG Campus lecturers in Penninsular Malaysia. This study also aims to identify the differences level of harmony based on demographic factors (gender, age, academic qualifications and service duration) among the lecturers. Data was collected by a cross-sectional survey through the Teacher Institution's Well-being Questionnaire (TIWEQ) constructed by the researchers. The questionnaire had also been tested for the validity and reliability. A total of 857 samples were involved in this study. The findings of the study showed that the level of harmony among IPG campus lecturers in Peninsular Malaysia is at a high level of 53.2 percent (n = 456). Based on the dimensions, it was found that the highest mean value is the self-motivation dimension (M = 3.68, SD = 0.38) while the lowest mean value is the personal health dimension (M = 2.79, SD = 0.59). This finding contributes to the field of knowledge that the importance of balance between external and internal harmony for the sustainability of the education system. In addition, it is also necessary to create a harmony profile for each IPG.
Decolonising and democratising Malawian public health
Authors: Nyalapa McDonald W. , Conn Cath , Nayar Shoba
Published: July 2023

Introduction. Transformative public health must move from its historically overly Eurocentric and professionally driven orientation towards local-contextualised, community-based health, empowerment and codesign of health research. Like many Pacific nations, Malawi is experiencing changes in its food systems which has health implications for Malawi people. This study sought to democratise and ‘open up’ the exploration of family eating through a photovoice collaboration with Malawian families with a view to understanding the links to a newly emerging and serious public health problem—that of diabetes.
Methods. Four families located in a semi-rural district of Blantyre, Malawi were recruited and images were collected using phones by younger family members to create a photo food diary of breakfast, lunch, and dinner eaten in the home. Using the photos as a prompt, focus group discussions were undertaken with each family exploring past and current eating patterns, and eating concerns for health.
Results. Thematic analysis of the photos and focus group transcripts revealed that staples, such as maize and sorghum, are still important in family eating. However, there is a worrying increase in consumption of obesogenic, processed foods such as sweetened beverages and snacks.
Conclusion. Malawi is currently experiencing a ‘nutritional transition’ brought about by commercialisation of food and the growing threat to a sustainable and healthy food system from climate change. Drawing on indigenous wisdom, this study argues that co-designed research methodologies, such as photovoice, are necessary to empower communities’ collaboration in shaping issues of their own health.
El perfil de egreso del doctorado en derecho de universidades latinoamericanas
Authors: González Aguilar Hugo
Published: July 2023

El presente estudio tiene como objetivo analizar el perfil de egreso del doctorado en derecho de las universidades latinoamericanas, que han explicitado la información a través de su página web, con base en el ranquin Scimago 2020. Se ha realizado un análisis documental cualitativo de los perfiles a través del programa Atlas ti. Las competencias o capacidades se han dividido en categorías: investigación (básica, aplicada, interdisciplinar), solución de problemas jurídicos, ejercicio docente, gestión (académica e investigativa), diseño de normas y políticas públicas. Las instituciones enfatizan en la investigación como base para la docencia, resolución de problemas y gestión académica.
Estado social de derecho como parámetro hermenéutico
Authors: Córdoba Chamorro Catherine
Published: July 2023

Este artículo describe cómo la evolución del Estado de Derecho a Estado Social de derecho generó entre otros escenarios jurídicos un cambio en la interpretación de la norma, así las cosas, el surgimiento de tal concepto y los elementos que lo conforman, no solamente deben ser considerados como disposiciones normativas constitucionales, sino también como parámetro hermenéutico para procesos de creación y aplicación normativa.
Si bien, dentro de procesos interpretativos se encuentra un abanico de métodos, es importante considerar la importancia y alcance que ostenta el concepto de Estado social de derecho como uno de aquellos, esto por cuanto al encontrarnos en un Estado Constitucional los criterios dispuestos en la norma de normas y de acuerdo al principio de juridicidad, tales parámetros deben acatarse en distintos escenarios dentro del ámbito jurídico.
Proses Manufaktur Mesin Pengering Cengkeh Rajangan Dengan Sistem Pemanas Heater
Authors: Prayuda Febry , Kabib Masruki , Hudaya Akhmad Zidni
Published: July 2023

ABSTRAK pengering sendiri adalah mesin tepat guna, dimana mesin ini berfungsi untuk mengeringkan produk – produk pertanian. Kebutuhan mesin pengering cengkeh rajangan dengan menggunakan energy listrik.Tujuan dari penelitian ini adalah Membuat Mesin Pengering Cengkeh Rajangan dengan sistem pemanas heater. Dengan adanya mesin pengering cengkeh ini, maka diharapkan bisa meningkatkan jumlah produksi serta meningkatkan kualitas produksi cengkeh, sehingga perusahaan tidak khawatir terjadi penurunan mutu yang disebabkan oleh kurang maksimalnya pemanfaatan teknologi yang ada.Metode eksperimen pada pembuatan mesin pengering ini meliputi kajian pustaka, gambar kerja, perancangan manufaktur, proses manufaktur, dan kemudian dilakukan uji fungsional untuk memastikan apakah rancang bangun mesin pengering cengkeh rajangan berfungsi dengan baik atau tidak.Hasil penelitian adalah mesin yang mampu mengeringkan cengekeh dengan cara bergerak berputar menggunakan sistem pemanas heater dengan kapasitas10 kg/proses menghasilkan cengkeh kering dengan kadar air 12%Kata kunci : Manufaktur, Mesin Pengering, cengkeh.
EVALUASI UNJUK KERJA MESIN ROLL AKRILIK
Authors: Amin Amilatul , Hudaya Akhmad Zidni , Wibowo Rianto
Published: July 2023

RINGKASANProses pembentukan atau bending akrilik yang berguna untuk membentuk akrilik sesuai dengan kebutuhan. Dalam proses pengolahan akrilik, dibutuhkan berbagai macam alat alat penekuk akrilik (acrylic bending machine). Salah satu proses dari pengolah akrilik adalah proses bending yang berguna untuk membentuk akrilik sesuai dengan kebutuhan...Metodologi penelitan dengan melakukan ekperimen menggunakan mesin roll akrilik dengan dimensi ketebalan akrilik 2mm, 3mm dan 4mm dan temperature yang digunakan 90 oC, 95 oC, dan 100 oC (range plastis) serta variasi jarak penekanan antara roll A dan roll BC yaitu: 25 mm, 35mm dan 55mm. Alat yang digunakan adalah thermogun untuk mengukur suhu pengerjaan dari mesin roll akrilik. Pada alat pengerolan bending akrilik yang dibuat penulis menghasilkan kalor tertinggi sebesar 19929 J pada ketebalan 4 mm pada suhu 1000C dan yang terendah 14892 J pada  ketebala 2 mm pada suhu 900C. 2.            Efisiensi laju pemanasan untuk alat pengerolan akrilik adalah sebesar 0,387 cm/s Kata kunci : Akrilik, Roll, Bending
PENGARUH VARIASI BILAH PISAU DAN GAYA TEKAN TERHADAP HASIL PEMBELAHAN BAMBU
Authors: Rustianto Dedy , Qomaruddin Qomaruddin , Wibowo Rianto
Published: July 2023

RINGKASAN Mesin pembelahan bambu merupakan salah satu mesin pengolah bambu yang dimanfaatkan untuk meringankan pekerjaan para pengrajin bambu rumahan, mesin tersebut digunakan ketika melakukan aktivitas pembelahan bambu yang merupakan teknik pengolahan yang paling menonjol dalam pengolahan bambu.                Mesin pembelah bambu dengan menggunakan sistem pneumatik lebih efisien dan cepat untuk proses pembelahan dengan mengukur tekanan udara pada kompresor, tekanan udara yang digunakan adalah 4 Bar, 6 Bar, 8 Bar, mesin ini menggunakan belahan pisau 10 bilah dan menggunakan sudut baji pisau 45° dan 55°.                Efisiensi mesin pembelah bambu sistem pnuematik pada proses pembelahan bambu dengan jenis bambu apus, bambu manis, bambu ori, dan bambu wulung, jika tekanan semakin besar maka kapasitas yang dihasilkan mesin lebih banyak. Jadi penggunaan tekanan udara pada proses pembelahan bambu adalah 4 bar, 6 Bar, dan 8 Bar yang lebih efisien adalah tekanan 8 bar               Kata kunci :jenis bambu, kompresor, mesin pembelah bambu, pneumatik, bilah pisau, sudut baji pisau ABSTRACT                    The bamboo splitting machine is one of the bamboo processing machines that is used to ease the work of home bamboo craftsmen, the machine is used when carrying out bamboo splitting activities which is the most prominent processing technique in bamboo processing.                    Bamboo splitting machine using a pneumatic system is more efficient and faster for the cleavage process by measuring the air pressure on the compressor, the air pressure used is 4 Bar, 6 Bar, 8 Bar, this machine uses a 10 blade cleavage blade and uses a knife wedge angle of 45° and 55°.                    The efficiency of the pneumatic system of bamboo splitting machine in the process of splitting bamboo with types of apus bamboo, sweet bamboo, ori bamboo, and wulung bamboo, if the pressure is greater, the capacity produced by the machine is more. So the use of air pressure in the bamboo splitting process is 4 bar, 6 Bar, and 8 Bar which is more efficient at 8 bar Keywords: type of bamboo, compressor, bamboo splitting machine, pneumatic, knife blade, knife wedge angle
Dampak Model Pembelajaran Auditory, Intellektualy, Repatition (Air) Terhadap Minat Belajar Siswa
Authors: Rizkiardi Reza Miftah , Subali Bambang
Published: July 2023

The purpose of this study was to determine the impact of the Auditory, Intellectualy, Repatition (AIR) learning model on the interest in learning science subjects in class III SDN 02 Banjaran. The background of this study was conducted to see whether there was an impact and change in the interest in learning science students in third grade SDN 02 Banjaran when the teacher used the Auditory, Intellectualy, Repatition (AIR) learning model. This type of research is descriptive qualitative research. The research method used is the survey method, the techniques used are interviews and observations. The results of the study based on interviews and observations of teachers and students showed the impact of changes in interest in learning science subjects in weather material and their influence on third grade students of SDN 02 Banjaran when teachers in learning use Auditory, Intellectualy, Repatition (AIR) learning models.
Meningkatkan Keterampilan Dan Hasil Belajar Bahasa Indonesia Tentang Menulis Surat Resmi Melalui Contextual Teaching And Learning (CTL) Pada Siswa Kelas VI SD 6 Getassrabi
Authors: Sulistyowati Endang
Published: July 2023

The skill of writing official letters and the results of his studies in class VI of SD 6 Getassrabi is very low. It is known that student skills are only 37% with learning completeness only 44%. Based on this, an action is taken to improve it, namely research by applying the Contextual Teaching and Learning (CTL) model. From the implementation of the study it was found that through the application of the CTL model students' skills and learning outcomes increased. Student writing skills become 81%, with completeness of student learning outcomes reaching 88%.
Side-effects of a number of insecticides on predatory mites in apple orchards
Authors: Malagnini Valeria , Baldessari Mario , Duso Carlo , Pozzebon Alberto , Angeli Gino
Published: July 2023

Background: Amblyseius andersoni is a common predatory mite occurring in fruit orchards located in Europe and North America. Its role in preventing spider mite outbreaks is widely recognized, in particular when selective pesticides are used. The compatibility between plant protection products and predatory mites is crucial to preserve their activity. There is a need to investigate the effects of pesticides on beneficials using multiple approaches.
Objectives: Field and laboratory experiments were conducted to evaluate the effects of a number of insecticides on A. andersoni.
Methods: The effects of neonicotinoids (i.e., acetamiprid, imidacloprid, thiacloprid, thia-methoxam) were compared with those of pyrethroids (i.e., tau-fluvalinate), well known for their negative impact on predatory mites. Insecticides were applied 1-3 times in an experimental fruit orchard located in Northern Italy. Laboratory trials focused on their effects on the survival and the fecundity of predatory mite females.
Results: Field experiments showed a decline in predatory mite numbers in plots treated with neonicotinoids or tau-fluvalinate compared to the untreated control. However, predatory mites in neonicotinoid plots reached higher densities compared to those recorded in tau-fluvalinate plots. Spider mite (Panonychus ulmi) populations reached moderate to high densities in plots treated with tau-fluvalinate while their densities were negligible in the remaining plots. Amblyseius andersoni survival was moderately affected by some neonicotinoids in the laboratory while they significantly reduced predatory mite fecundity. In contrast tau-fluvalinate exerted severe effects on survival and fecundity of predatory mites. Finally, escaping rate increased after pesticide exposure suggesting possible alterations in predatory mite behavior.
Conclusions: Neonicotinoid applications significantly affected predatory mite densities in field conditions and this phenomenon appeared to be influenced by their impact on female fecundity. Their effects on survival were less severe. Implications of these results for IPM tactics in fruit orchards are discussed.
Cardiovascular prevention in childhood: a consensus document of the Italian Society of Cardiology Working Group on Congenital Heart Disease and Cardiovascular Prevention in Paediatric Age
Authors: Martino Francesco , Bassareo Pier Paolo , Martino Eliana , Romeo Francesco , Calcaterra Giuseppe , Perrone Filardi Pasquale , Indolfi Ciro , Nodari Savina , Montemurro Vincenzo , Guccione Paolo , Salvo Giovanni Di , Chessa Massimo , Pedrinelli Roberto , Mercuro Giuseppe , Barillà Francesco
Published: July 2023

Cardiovascular diseases (CVD) may be manifested from a very early age. Genetic and environmental (epigenetic) factors interact to affect development and give rise to an abnormal phenotypical expression of genetic information, although not eliciting changes in the nucleotide sequence of DNA. It has been scientifically proven that increased oxidative stress (OS) caused by disease (overweight, obesity, diabetes), nutritional imbalances, unhealthy lifestyles (smoking, alcohol, substance abuse) in the mother during pregnancy may induce placental dysfunction, intrauterine growth restriction, prematurity, low birth weight, postnatal adiposity rebound, metabolic alterations and consequent onset of traditional cardiovascular risk factors.

OS represents the cornerstone in the onset of atherosclerosis and manifestation of CVD following an extended asymptomatic period. OS activates platelets and monocytes eliciting the release of pro-inflammatory, pro-atherogenic and pro-oxidising substances resulting in endothelial dysfunction, decrease in flow-mediated arterial dilatation and increase in carotid intima-media thickness. The prevention of CVD is defined as primordial (aimed at preventing risk factors development), primary (aimed at early identification and treatment of risk factors), secondary (aimed at reducing risk of future events in patients who have already manifested a cardiovascular event), and tertiary (aimed at limiting the complex outcome of disease). Atherosclerosis prevention should be implemented as early as possible. Appropriate screening should be carried out to identify children at high risk who are apparently healthy and implement measures including dietary and lifestyle changes, addition of nutritional supplements and, lastly, pharmacological treatment if risk profiles fail to normalise. Reinstating endothelial function during the reversible stage of atherosclerosis is crucial.
Efficacy of SGLT2-inhibitors across different definitions of heart failure with preserved ejection fraction
Authors: De Marzo Vincenzo , Savarese Gianluigi , Porto Italo , Metra Marco , Ameri Pietro
Published: July 2023

Aims

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been evaluated in phase 3 randomized–controlled trials (RCTs) that enrolled individuals with heart failure and preserved ejection fraction (HFpEF) based on detailed clinical, biochemical, and echocardiographic criteria (hereafter HF-RCTs), and in cardiovascular outcomes trials (CVOTs) in diabetic patients, in which the diagnosis of HFpEF relied on medical history.

Methods and results

We performed a study-level meta-analysis of the efficacy of SGLT2i across different definitions of HFpEF. Three HF-RCTs (EMPEROR-Preserved, DELIVER, and SOLOIST-WHF) and four CVOTs (EMPA-REG OUTCOME, DECLARE-TIMI 58, VERTIS-CV, and SCORED) were included, for a total of 14 034 patients. SGLT2i reduced the risk of cardiovascular death or heart failure hospitalization (HFH) in all RCTs pooled together [risk ratio 0.75, 95% confidence interval (95% CI) 0.63–0.89, NNT 19], in HF-RCTs (risk ratio 0.71, 95% CI 0.52–0.97, NNT 13), and in CVOTs (risk ratio 0.78, 95% CI 0.60–0.99, NNT 26). SGLT2i also decreased the risk of HFH in all RCTs (risk ratio 0.81, 95% CI 0.73–0.90, NNT 45), in HF-RCTs (risk ratio 0.81, 95% CI 0.72–0.93, NNT 37), and in CVOTs (risk ratio 0.78, 95% CI 0.61–0.99, NNT 46). By contrast, SGLT2i were not superior to placebo for cardiovascular death or all-cause death in all RCTs, HF-RCTs, or CVOTs. Results were comparable after excluding one RCT at a time. Meta-regression analysis confirmed that the type of RCT (HF-RCT vs. CVOT) did not influence the SGLT2i effect.

Conclusions

In RCTs, SGLT2i improved the outcomes of patients with HFpEF regardless of how the latter was diagnosed.
Trends in age and sex-specific dilated cardiomyopathy mortality in Italy, 2005–2017
Authors: Zuin Marco , Rigatelli Gianluca , Porcari Aldostefano , Merlo Marco , Bilato Claudio , Roncon Loris , Sinagra Gianfranco
Published: July 2023

Aims

Data regarding the dilated cardiomyopathy (DCM)-related mortality and relative time trends in the Italian population remain scant. We sought to assess the DCM mortality rates and relative trends among the Italian population between 2005 and 2017.

Methods

Annual death rates by sex and 5-year age group were extracted from the WHO global mortality database. The age-standardized mortality rates, with relative 95% confidence intervals (95% CIs), also stratified by sex, were calculated using the direct method. Joinpoint regression analyses were used to identify periods with statistically distinct log linear trends in DCM-related death rates. To calculate nationwide annual trends in DCM-related mortality, we assessed the average annual percentage change (AAPC) and relative 95% CIs.

Results

In Italy, the DCM age-standardized annual mortality rate decreased from 4.99 (95% CI: 4.97–5.02) deaths per 100 000 to 2.51 (95% CI: 2.49–2.52) deaths per 100 000 population. Over the entire period, men had a higher DCM-related mortality rates than women. Moreover, the mortality rate increased with age, with a seemingly exponential distribution and showing a similar trend among men and women. Joinpoint regression analysis revealed a linear decrease in age-standardized DCM-related mortality from 2005 to 2017 [AAPC: −5.1% (95% CI: −5.9 to −4.3, P < 0.001)] in the entire Italian population. However, the decline was more pronounced among women [AAPC: −5.6 (95% CI: −6.4 to −4.8, P < 0.001)] compared with men [AAPC: −4.9 (95% CI: −5.8 to −4.1, P < 0.001)].

Conclusion

In Italy, the DCM-related mortality rates linearly declined from 2005 to 2017.
Albumin use and mortality among intensive care patients with acute heart failure: a retrospective study
Authors: Yu Zhenze , Zhu Binghua , Ma Jianxin , Guan Yutin , Zhou Yiling , Li Hezhi , Zhang Jinping
Published: July 2023

Objective

Hypoproteinemia is common in patients with acute heart failure, especially in the intensive care unit (ICU). We assessed short-term mortality in patients with acute heart failure for albumin and nonalbumin users.

Methods

Our study was a retrospective, observational and single-center study. We included patients with acute heart failure from the Medical Information Mart for Intensive Care-IV and compared short-term mortality and length of hospital stay in patients with and without albumin use. We used propensity score matching (PSM) to adjust for confounders, a multivariate Cox proportional hazard regression model, and performed subgroup analysis.

Results

We enrolled 1706 patients with acute heart failure (318 albumin users and 1388 nonalbumin users). The 30-day overall mortality rate was 15.1% (258/1706). After PSM, the 30-day overall mortality was 22.9% (67/292) in the nonalbumin group and 13.7% (40/292) in the albumin group. In the Cox regression model, after propensity matching, the albumin use group was associated with a 47% reduction in 30-day overall mortality [hazard ratio (HR) = 0.53, 95% confidence interval (CI): 0.36–0.78, P = 0.001]. In subgroup analysis, the association was more significant in males, patients with heart failure with reduced ejection fraction (HFrEF), and nonsepsis patients.

Conclusion

In conclusion, our investigation suggests that the use of albumin was associated with lower 30-day mortality in patients with acute heart failure, especially in males, those aged >75 years, those with HFrEF, those with higher N-terminal pro-brain natriuretic peptide levels, and those without sepsis.
Mitral annular calcification as a predictor of stroke in the multiethnic study of atherosclerosis
Authors: Onuegbu Afiachukwu , Calicchio Francesca , Kinninger April , Nakanishi Rine , Carr John J. , Nasir Khurram , Gottesman Rebecca , Budoff Matthew
Published: July 2023

Background

Mitral annular calcification (MAC) is associated with an increased risk for cardiovascular morbidity and mortality. This study provides recent data on the association between cardiac computed tomography (CT) derived MAC and 15 years of stroke risk in a racially diverse cohort.

Methods

All multiethnic studies of atherosclerosis participants (n = 6814) who completed a cardiac CT at baseline were included in this analysis. MAC score was calculated from cardiac CT using the Agatston and volume score methods. Multivariable Cox proportional hazard regression models were used to compute hazard ratios for the association between MAC and stroke after adjusting for traditional cardiovascular risk factors, inflammatory markers, coronary artery calcium score, atrial fibrillation, and left atrial size.

Results

Overall, 9% of participants (644/6814) had MAC at baseline. Over a surveillance period of 15 years, 304 strokes occurred, and 79% were ischemic strokes. After adjusting for age, sex, race/ethnicity, SBP, diabetes, smoking, fibrinogen, IL-6, high-sensitivity C-reactive protein, and coronary artery calcium score, baseline MAC was associated with increased risk for all strokes [hazard ratio 1.68; 95% confidence interval (CI) 1.22–2.30: P = 0.0013]. When atrial fibrillation/flutter and left atrial size were included in the final multivariable model, MAC remained a predictor of all strokes (hazard ratio 1.93; 95% CI 1.22–3.05: P < 0.0051) and ischemic stroke (hazard ratio 2.03; 95% CI 1.24–3.31: P < 0.0046).

Conclusion

MAC is an independent predictor of long-term stroke risk in a racially diverse population beyond conventional cardiovascular risk factors and atrial fibrillation.
How Does the Supply of Tertiary Graduates Correlate with the Labour Market? Evidence from European Countries
Authors:   Bucharest University of Economic Studies, Bucharest, Romania, Ghiță Simona Ioana , Boboc Cristina-Rodica ,   Bucharest University of Economic Studies, Bucharest, Romania,   Institute of National Economy, Bucharest, Romania, Săseanu Andreea Simona ,   Bucharest University of Economic Studies, Bucharest, Romania, Vasile Valentina ,   Institute of National Economy, Bucharest, Romania
Published: July 2023

It is well-known that the education level has significant impact on employment prospects on the labor market. Despite a slight decrease in the number of tertiary graduates in 2018-2019, the year 2020, when the COVID-19 pandemic began, was marked by an increase in the indicator-level. In the long term, the supply of tertiary graduates registered an upward trend. The paper performs - in a note of originality - a cluster analysis of the European countries by the correlation between the evolution of the graduates with higher education and that of the employment rate of the highly qualified, in order to identify the main behavioral patterns. As a novelty element, the paper tests the hypothesis of the existence of statistically significant changes from the perspective of the share of tertiary graduates and that of the employment rate of highly educated, during the current pandemic crisis compared to the previous global financial crisis. The results indicated an important improvement only of the second indicator, which shows the need to develop policies to stimulate the youth to raise their education level, and thus improve the situation on the labor market, even in crisis times.
Radical Americas: A Hemispheric History of the Left
Authors: Beswick Spencer
Published: July 2023

This article argues that a transnational methodological approach is crucial to understanding the development of the radical Left across the hemisphere throughout the twentieth century. Historical accounts of the Left in the Americas typically divide their subject according to temporal, geographic, and ideological boundaries. This approach accentuates ruptures and ideological divisions while underemphasizing underlying continuities and broader historical trends. By synthesizing a hemispheric history of the Left in a new periodization that stretches from early regional anarchist networks through the rise and fall of the Pink Tide, this article demonstrates how a transnational approach enables a richer understanding of the historical developments underlying recent social movements and political upheavals. An emphasis on transnational networks encourages readers to identify not with our imperialist government but rather with alternative histories of grassroots solidarity and cooperation across borders. This framework provides a mode of engagement that decenters the importance of nation-states and focuses instead on the actions of ordinary people struggling to build a new world.
STUNTING DISASTER RISK REDUCTION EFFORTS IN INDONESIA THROUGH RISK COMMUNICATION
Authors: Hasmira Mira Hasti
Published: July 2023

Indonesia's inclusion in the prevalence of stunting by WHO poses an extraordinary threat to the future growth of the nation's children. The purpose of writing this article is to describe messages in risk communication that must be conveyed in disaster risk management efforts. Stunting can be categorized as a disaster, especially non-natural disasters because it has a psychological impact and is a threat to the growth of babies in Indonesia. This paper uses qualitative methods, to be a precise literature study in data collection. found that, In efforts to reduce disaster risk (DRR), three factors serve as a reference and must be studied to determine the stages of disaster management, namely threat, vulnerability, and capacity for stunting. This is the main message and communication of the risk of stunting in Indonesia.
Development of the Quality of Professional Training of Polygraph Examiners in the System of Departmental Education of the Ministry of Internal Affairs of Russia
Authors: Sadekov Rustem Rafekovich
Published: July 2023

The author in his work explores a number of issues related to the development of the quality of professional training of polygraph examiners in the system of departmental education of the Ministry of Internal Affairs of Russia. The current organizational, pedagogical, legal mechanisms and tools that can be used for the successful development and improvement of professional training in this field of activity of employees of the internal affairs bodies of the Russian Federation are considered. The main emphasis is placed on the importance of the formation of high-quality educational content, the use of successful methods and approaches to the training of polygraph examiners. Attention is drawn to the existence of a mandatory requirement for scientific experience, practical and pedagogical component of specialists, carrying out educational activities. Recommendations for improving aspects of vocational training are given. The main conclusions of the conducted research are related to the constant improvement of the level of their education and skills by polygraph examiners, which are based on such pedagogical and organizational aspects as the formation of skills and abilities in the legal sphere. It is noted that there is a need for interaction and cooperation on a permanent basis with educational organizations of the Ministry of Internal Affairs of Russia, other law enforcement universities, invited practitioners with extensive practical experience in preparing and conducting special psychophysiological studies using polygraph devices in various fields and areas. All these measures will dramatically affect the quality results of the work of polygraph examiners of the Ministry of Internal Affairs of Russia.