bluuebunny/crossref_metadata_2025 huggingface dataset:
Defect detection on inductive thermography images using convolutional neural networks
Authors: Tout karim , Bouteille patrick
Published: June 2023

Inductive infrared thermography has been proven as an interesting solution for the inspection of surface defects. However, inductive thermography images can be noisy or present large variations in contrast and texture. Combine that with the large variability in surface defects shapes, sizes and types, the defect detection task becomes very complex. Defect detection methods based on convolutional neural network (CNN) proved their efficiency for complex detection tasks. This paper discusses two main approaches of defect detection with CNN : classification and object detection. Detection results are presented along with the advantages and weaknesses of each approach for real-time defect detection
Simple Statistics And Frame Interpolation, On The Task of Defect Enhancement, in Carbon Fiber Reinforced Plastic and Cultural Heritage.
Authors: Fleuret julien R. , Ebrahimi samira , Ibarra-Castanedo clemente , Sfarra stefano , Lopez fernando , Maldague xavier P.v.
Published: June 2023

This paper investigates the use of the InterQuartile Range (IQR) as a defect enhancement method for pulsed ther-mography thermograms. The interest of the IQR as a defect enhancement method is directly related to the frequency of the acquisition; for this reason, this paper also investigates its application in association with the frame interpolation (aka generative) algorithm. The interest of the IQA is its ability to enhance defective regions while having a computational cost lower than common dimensionality reduction methods. The method’s validity is demonstrated using a test sample of Carbon Fiber Reinforced Plastic (CFRP), while a possible application to cultural heritage is also studied.
Temperature measurements of opaque materials at high temperatures using multi-spectral methods
Authors: Ennass kamal , Remy benjamin , Schick vincent , Meulemans johann
Published: June 2023

Precise and accurate temperature measurements during material manufacturing processes are crucial for obtaining the desired properties. In the context of this study, the metrological tool used for the measurements will be the multi-spectral infrared thermography. This non-intrusive tool is coupled with the Particle Swarm Optimization algorithm (PSO algorithm) for the simultaneous estimation of temperature and spectral emissivity variations in the case of opaque bodies by using an analytical model based on finite elements parametrization.
Polak na Antylach – Kazimierz Lux i jego opisanie San Domingo
Authors: Zajkowska Joanna
Published: June 2023

The article discusses Kazimierz Lux’s travel entitled The description of the island of San-Domingo, which was published „Biblioteka Warszawska” in 1854 (v. 4, p. 197–223). It is a paraliterary notation of the stay of the „Polish pirate” in the Antilles, where, as a soldier of the French 114 th brigade formed by Napoleon, he suppressed the slave uprising. Lux’s text is a fairly detailed study of San-Domingo’s climatic, geographical and living conditions, plant crops and livestock; however, above all, it is a fascinating record of a Pole’s encounter from the early nineteenth century with the exoticism of the second hemisphere
Odyseusz – bohater o wielu twarzach (na podstawie Odysei Homera i Powrotu Odysa Stanisława Wyspiańskiego)
Authors: Wilczak Wiktoria
Published: June 2023

The Return of Odysseus is a multifaceted drama, which speaks about the fate ofman, about the impossibility of escaping from destiny. It is an interpretation ofthe Odyssey according to Wyspianski. Completely different, stripped of hypocrisy,true, showing a man, not a hero. It is also the most beautiful example of how muchthe playwright based his work on the legacy of antiquity, how much Greek culturemattered to him. It shows an incredible admiration and desire to understand antiquity, but also a desire to find in it himself, his own views, philosophy, spiritualpath. Wyspianski proves that one’s own interpretations can lead to the discovery ofnew aspects of already known works. Every difference shown in this article proveshow strong a link the two works share
LncRNA SNHG25 Predicts Poor Prognosis and Promotes Progression in
Osteosarcoma via the miR-497-5p/SOX4 Axis
Authors: Wan Ningjun , Liu Qiang , Shi Jiandang , Wang Siliang
Published: June 2023

Background:

Osteosarcoma is a disease that primarily affects adolescents with skeletal
immaturity. LncRNAs are abnormally expressed and correlated with osteosarcoma patients' prognosis.
We identified aberrant expression of LncRNA SNHG25 (small nucleolar RNA host gene 25)
in osteosarcoma and analyzed the molecular mechanisms by which it regulates osteosarcoma progression.

Methods:

The expression levels of SNHG25 in tumour specimens and cells were measured by RTqPCR.
Loss-of-function assays were conducted to investigate the functional role of SNHG25 in
vitro and in vivo. Bioinformatic predictions, dual-luciferase reporter assays, and western blotting
were performed to explore the possible underlying mechanisms.

Results:

SNHG25 was highly expressed in osteosarcoma cells and tissues. The Kaplan–Meier
curve showed that the survival rate of patients with high SNHG25 expression was significantly
lower than those with low SNHG25 expression. Functional studies have indicated that inhibition of
SNHG25 suppresses cell proliferation, migration, and invasion, while promoting apoptosis.
SNHG25 knockdown suppresses osteosarcoma tumour growth in vivo. SNHG25 functions as a
sponge for miR-497-5p in osteosarcoma cells. The level of SNHG25 was negatively correlated
with that of miR-497-5p. The proliferation, invasion, and migration of osteosarcoma cells were
restored by transfection of the miR-497-5p inhibitor in the SNHG25 knockdown group

Conclusion:

SNHG25 was determined to function as an oncogene by promoting osteosarcoma cell
proliferation, invasion, and migration through the miR-497-5p/SOX4 axis. Upregulation of
SNHG25 expression indicated poor prognosis in patients with osteosarcoma, which showed that
SNHG25 may serve as a potential therapeutic target and prognostic biomarker in osteosarcoma.
Naloxone Effects Against Cutaneous Leishmaniasis Caused by Leishmania
major Strain MRHO/IR/75/ER in the BALB/c Mice
Authors: Azizi Hakim , Mahdavinik Elham , Hataminejad Maryam , Khamesipour Ali , Montazeri Sareh
Published: June 2023

Introduction::

Cutaneous leishmaniasis (CL) is a serious health problem in some parts of the world, such as Iran. Since the use of pentavalent antimonial compounds such as meglumine antimoniate (Glucantime, MA) for the treatment of CL has side effects, naloxone as a new treatment in the footpad of Leishmania major (L. major)-infected BALB/c mice was investigated by evaluating the lesion size and the parasite burden.

Method::

The animals were infected with L. major (MRHO/IR/75/ER). 40 BALB/c mice were divided into 4 groups (10/group), and were treated as follows 39 days after L. major infection: Group 1 treated with intraperitoneal injections of MA (100 mg/kg, positive control group) daily for six weeks; Group 2 received a 100 μl injection of PBS (negative control group); Group 3 received subcutaneous (SC) injections of naloxone (10 mg/kg) daily for six weeks (Naloxone1), and Group 4 was SC injected with naloxone (10 mg/kg) weekly for six weeks (Naloxone2). The lesion size was measured using a digital caliper.

Result::

After the end of treatment, the lesion parasite burden was evaluated. As compared to the negative control group, the groups that received MA and naloxone (groups 1, 3, and 4) showed fewer parasites.

Conclusion::

Also, the naloxone-treated mice showed significantly smaller lesion sizes than the negative control group (p˂0.05), but they did not differ significantly from the MA-treated mice. Taken together, the results suggest that naloxone might be a promising and alternative treatment for CL.
Evaluation of BRAF Mutations in Patients with Colorectal Cancer in
the East of Iran
Authors: Serki Elham , Mansouri Atena , Malekaneh Mohammad , Naseri Mohsen
Published: June 2023

Background:

Several genetic alterations in cell growth regulatory genes, such as
BRAF, are associated with colorectal cancer. Due to the introduction of biological agents
designed to treat cancer, diagnostic tests using nucleic acids extracted from formalin-fixed
and paraffin-embedded tissues are becoming more common.

Objective:

This study aimed to determine the incidence of BRAF mutations in colorectal
cancer patients.

Materials and Methods:

50 paraffin-embedded cancer specimens were obtained from Imam
Reza Hospital of Birjand in Iran. PCR was used to amplify and sequence the BRAF gene
exon 15, which was extracted from paraffin-embedded tissue using an improved technique.

Results:

2/43 (4%) of patients with colorectal cancer exhibited the BEAF V600E mutation.
Most of the mutations occurred in patients over 50 years of age.

Conclusion:

To understand how genetics and environment interact to influence the low incidence
of BRAF mutations in the east of Iran, further research is needed to determine what
is driving this low incidence of BRAF mutations and what factors contribute to it.
The Role of the most Important Fruits in the Prevention and Treatment of
Cardiovascular Diseases in Persian Traditional Medicine
Authors: Abazari Mohammad , Gholoobi Arash , Derakhshan Ali Reza , Saeedinejat Shahin , Yousefi Mahdi
Published: June 2023

Cardiovascular diseases (CVD) are the leading cause of health problems worldwide.
CVD are defined as conditions affecting the heart and blood vessels. Mortality due to cardiovascular
diseases has increased in recent years. However, they can be easily controlled by reducing risk
factors, including lipid profile, blood pressure, tobacco, alcohol, and low physical activity. Fruits
have an important role in improving the risk factors of CVD. Ancient medical sources can play an
important role in generating ideas for new research. In this study, the most common fruits that have
been recommended by Persian traditional physicians in patients with CVD were reviewed. New
documents supporting these effects were also extracted through a search on electronic databases.
The findings showed that some fruits have a therapeutic role in CVD, according to Persian traditional
medicine. Old Persian traditional physicians, such as Avicenna, advised fruits, including apples,
lemon, pomegranate, pineapple, quince, cucumber, plums, and citron, for the treatment of
CVDs. Several studies have been carried out on the effects of the above fruits, including apple (Malus
pumila), pomegranate (Punica granatum), pineapple (Ananas comosus), Quince (Cydonia oblonga
Mill.), fig (Ficus carica L.), and olive (Olea europaea). Modulation of signaling pathways
and molecular properties that leads to reducing lipid metabolism disorders, correcting endothelial
dysfunction, reducing blood pressure, reducing oxidative stress, and suppressing inflammation responses
are the major mechanisms conducted by these fruits in preventing CVD. These pieces of
evidence show that the opinion of Iranian medicine physicians regarding choosing fruits for treating
CVD is worthy of consideration and an entry for deriving hypotheses for future studies.
Development and Validation of RP-HPLC Method for the Estimation of
Tenofovir and Emtricitabine in Bulk and Pharmaceutical Dosage Form
Authors: Sahoo Biswa Mohan , Rao Pallepogu Venkateswara , Rao Naidu Srinivasa
Published: June 2023

Background:

A novel, simple, efficient, rapid, and precise reverse-phase highperformance
liquid chromatography (RP-HPLC) method was developed for the estimation of
Tenofovir and Emtricitabine in the bulk and pharmaceutical dosage form. The currently developed
method was subsequently validated according to ICH guidelines in terms of linearity, accuracy,
precision, the limit of detection, the limit of quantification, robustness, etc.

Methods:

The separation of the selected drugs was optimized after several trials including change
of mobile phase and its composition, stationary phase, flow rate, column temperature, etc. The
separation was performed by using an Inertsil ODS C18 column (250 mm x 4.6 mm, 5μ) and UV
absorption was measured at 231 nm. Methanol: Acetonitrile: Water was selected as the mobile
phase in the ratio of 50:20:30 (V/V/V) at a flow rate of 1 mL/min. As per International Conference
on Harmonization (ICH) Q2 R1 guidelines, several validation parameters were evaluated
which include specificity, linearity, precision, accuracy, the limit of detection (LOD), and the limit
of quantitation (LOQ).

Results:

The acceptable degree of linearity range was found to be 40-100 μg/mL. The standard solution
exhibited retention times of 3.06 minutes and 5.07 minutes for Tenofovir and Emtricitabine respectively.
The LOD and LOQ obtained were 0.05 μg/ml and 0.02 μg/mL, 15 μg/mL, and 0.08 μg/mL for
Tenofovir and Emtricitabine respectively. The percent recovery was found to be 98 to 102%.

Conclusion:

Hence, the proposed method is simple, selective, and specifically meets the requirements
of ICH guidelines for the validation of the analytical method.
Transformasi Digital Layanan Kepegawaian Pemerintah Daerah Kota Cirebon: Studi Kasus Kebijakan Sistem Administrasi Manajemen Pemerintahan (SAMPEAN)
Authors: Hermawan Kurnia Tri , Pusparani Indah Gilang , Solihudin Dodi
Published: June 2023

Penelitian ini bertujuan untuk mengkaji bagaimana kebijakan transformasi digital layanan kepegawaian di lingkungan Pemerintah Daerah Kota Cirebon. Menggunakan metode deskriptif kualitatif, penelitian ini menganalisis bagaimana Pemerintah Daerah Kota Cirebon menyelenggarakan Sistem Pemerintahan Berbasis Elektronik (SPBE) di bidang layanan kepegawaian yang diperkuat dengan dukungan regulasi-regulasi. Berangkat dari kesulitan-kesulitan untuk layanan kepegawaian secara manual dalam sistem manajemen kepegawaian ASN yang berbasis kinerja, diluncurkanlah aplikasi SAMPEAN yang menjadi dashboard untuk seluruh informasi kepegawaian di Kota Cirebon. Informasi kinerja berupa presensi dan laporan kerja harian, dan perhitungan tambahan penghasilan pegawai yang semakin real-time, akurat, transparan, dan adil. Selanjutnya, dengan pengembangan kebutuhan akan kelengkapan aplikasi sekaligus penyederhanaan platform, pada tahun 2022, melalui kebijakan layanan administrasi pemerintahan berupa Perwal Kota Cirebon Nomor 52 Tahun 2022 tentang Portal Layanan Berbasis Elektronik Terintegrasi di Lingkungan Pemerintah Daerah Kota Cirebon, maka aplikasi SAMPEAN bertransformasi dengan menambah layanan kepegawaian, kinerja, kearsipan, dan layanan pemerintahan lainnya. Keberadaan layanan aplikasi SAMPEAN yang bisa diakses langsung oleh pengguna (ASN) merupakan bentuk implementasi transformasi digital dalam kebijakan kepegawaian dan manajemen pemerintahan lingkungan Pemerintah Daerah Kota Cirebon.
Symposiumverslag NVSST 2023
Authors: Van Brenk Frits
Published: June 2023

Een verslag van het jaarlijkse symposium van de Nederlandse Vereniging voor Stem-, Spraak- en Taalpathologie (NVSST) gehouden op vrijdag 10 maart 2023.
Nuevos registros de Scolytinae (Coleoptera: Curculionidae) en bosques templados de Durango
Authors: Fernández-García Jorge Alberto , Marrufo-Madrid Raúl , Equihua-Martínez Armando , Estrada-Venegas Edith Guadalupe , Segura-León Obdulia Lourdes
Published: June 2023

En estudios previos realizados en Durango se han reportado 115 especies de escolitínos, la mayoría en bosques templados cercanos a las carreteras principales. Desde el trabajo publicado por Wood (1982) a la fecha se han agregado solo ocho especies. El presente trabajo se realizó de diciembre de 2019 a noviembre de 2020 utilizando trampas Ecoiapar cebadas con etanol. La mayor riqueza especifica fue de ocho especies en el sitio cuatro, mientras que la menor correspondió al sitio dos con cinco especies. Por otra parte, la mayor abundancia fue en el sitio seis con 119 capturas, siendo Monarthrum tuberculatum la especie más abundante durante el estudio. Se reportan 13 nuevos registros estatales Corthylus burgosi, C. nudus, Hylocurus femineus, Hylurgops longipennis, Monarthrum ca. scutellare, M. dentigerum, M. huachucae, M. tuberculatum, M. xalapensis, Pityophthorus ca. miniatus, P. cacuminatus, P. infulatus, P. virilis, Pseudopityophthorus granulatus, y una para México, Pityophthorus infulatus. Los resultados representan un aumento del 12.17 % de la riqueza conocida para el estado de Durango, respecto a las 115 especies registradas previamente, lo que asciende a un total de 129 especies para el estado.
Способ определения конфигурации защитной пленки при численном моделировании пульсационных режимов конвективно-пленочного охлаждения
Authors: Тукмаков А.Л. , Ахунов А.А. , Тукмакова Н.А. , Харьков В.В.
Published: June 2023

Presented is a method of determining the configuration of a protective film during numerical modeling of systems convective-film cooling on the example of double-sided flow around the plate with high-temperature and cooling flows communicating through an inclined slit channel that connects the regions cooling and high-temperature gas flow. Gas dynamic field calculations were performed for both of the plate side, and the configuration of the cooling film in the pulsating supply of the cooling film is described air.
Портативный нейтронный генератор на лазерно-плазменном ионном диоде с магнитной изоляцией
Authors: Степанов Д.С. , Козловский К.И. , Скрипник А.П. , Школьников Э.Я.
Published: June 2023

The article presents a new experimental portable pulsed neutron generator based on a laser-plasma ion diode with magnetic insulation and the results of the first experiments. The laser-plasma diode makes it possible to obtain large ion current pulses that generate high-intensity neutron radiation. The source of optical radiation was a pulsed neodymium-doped yttrium aluminum garnet laser with a wavelength of 1064 nm, a pulse energy of up to 0.7 J, and a duration of ~10 ns. The ion beam is accelerated by an Arkadiev-Marx pulsed voltage generator with a voltage amplitude of up to 250 kV, a duration of up to 1.5 µs, and an energy of up to 160 J. Neutrons were generated using the reaction d(d,n)3He. A neutron yield of 2·107 neutron/pulse was obtained.
Трехмерная ловушка с возбуждением колебаний ионов на границе устойчивости диаграммы Матье
Authors: Мамонтов Е.В. , Дятлов Р.Н.
Published: June 2023

Vibrations of charged particles in compositions of three-dimensional high-frequency quadrupole and static homogeneous electric fields in the stable region and in the vicinity of the stability boundary of the Mathieu diagram are investigated. Using a pseudopotential model of a rapidly oscillating field, it is shown that the motion of charged particles during linear scanning of a secular frequency is described by the Airy differential equation. Based on the properties of solutions of the Airy equation, a method of ion mass separation with resonant excitation of oscillations at the stability boundary of the Mathieu diagram has been developed. To implement the method, the ion-optical system of the three-dimensional trap is supplemented with corrective electrodes. Computer modeling has determined the optimal potentials of the correcting electrodes, at which the errors of the distributions of quadrupole and homogeneous fields do not exceed 10E-4 and 2·10E-3. Keywords: superposition of quadrupole and homogeneous fields, Airy differential equation, mode of resonant excitation of oscillations, three-dimensional ion trap with correcting electrodes.
Influence of Bifunctional PtZn/SiO2 and H-ZSM-5 Catalyst on the Rates and Selectivity of Propene Aromatization
Authors: Russell Christopher K. , Saxena Arunima , T. Miller Jeffrey T.
Published: June 2023

Previous studies on the conversion of olefins to aromatics with bifunctional Ga- or Zn-ZSM-5 catalysts have concluded that benzene, toluene, and xylenes (BTX) yields are significantly higher than for ZSM-5 alone. These results were attributed to the higher aromatic dehydrogenation rate of Ga or Zn. In this study, a highly active, bifunctional PtZn/SiO2 (1.3 wt% Pt, 2.6 wt% Zn) with H-ZSM-5 (Si/Al = 40) catalyst is investigated for propene aromatization at 723 K and 823 K. At low to moderate propene conversions, in addition to BTX, small alkanes and olefins are produced. Many of these may also be converted to aromatics at higher propene conversion while others are not, for example, methane, ethane and propane. When compared at equivalent space velocity or propene conversion, the bifunctional catalyst has a much higher selectivity to aromatics than ZSM-5; however, when compared at equivalent conversion of all reactive intermediates, the bifunctional catalyst exhibits very similar BTX selectivity. At 723 K, for ZSM-5 the primary non-reactive by-products are propane and butane; while, for the bifunctional catalyst the major non-reactive product is propane. At 823 K, both ZSM-5 and the bifunctional catalyst convert propane and butane to aromatics increasing the aromatic yields, and the by-products are methane and ethane.
Co-Constructing a Community-Based Telemedicine Program for People With Opioid Use Disorder During the COVID-19 Pandemic: Lessons Learned and Implications for Future Service Delivery
Authors: Høj Stine Bordier , de Montigny Catherine , Chougar Sofiane , Léandre Robert , Beauchemin-Nadeau Marie-Ève , Boyer-Legault Geneviève , Goyette Amélie , Lamont Sara-Kim , Bruneau Julie
Published: June 2023

The COVID-19 pandemic triggered unprecedented expansion of telemedicine, including in the delivery of opioid agonist treatment (OAT) for people with opioid use disorder (OUD). However, many people with OUD lack the technological resources necessary for remote care, have complex needs, and are underserved, with precarious access to mainstream services. To address the needs of these individuals, we devised a unique program to deliver OAT via telemedicine with the support of community outreach workers in Montreal (Quebec, Canada). The program was co-constructed by the service de médecine des toxicomanies of the Centre hospitalier de l’Université de Montréal (CHUM-SMT)—a hospital-based addiction medicine service—and CACTUS Montréal—a community-based harm reduction organization known and trusted by its clientele. All procedures were jointly developed to enable flexible and rapid appointment scheduling. CACTUS Montréal workers promoted the program, facilitated private on-site telemedicine connections to the CHUM-SMT, accompanied patients during web-based appointments if requested, and provided ongoing holistic support and follow-up. The CHUM-SMT offered individualized OAT regimens and other health services as needed. Overall, our experience as clinicians and community-based workers intimately involved in establishing and running this initiative suggests that participants found it to be convenient, nonjudgmental, and responsive to their needs, and that the implication of CACTUS Montréal was highly valued and integral to patient engagement and retention. Beyond the context of the COVID-19 pandemic, similar programs may present a flexible and accessible means to deliver alternative treatment options for people with OUD disengaged from traditional care, bridge gaps between communities and health providers, and improve access to care in rural or remote settings.
Topics in Antivax and Provax Discourse: Yearlong Synoptic Study of COVID-19 Vaccine Tweets
Authors: Zaidi Zainab , Ye Mengbin , Samon Fergus , Jama Abdisalan , Gopalakrishnan Binduja , Gu Chenhao , Karunasekera Shanika , Evans Jamie , Kashima Yoshihisa
Published: June 2023

Background

Developing an understanding of the public discourse on COVID-19 vaccination on social media is important not only for addressing the ongoing COVID-19 pandemic but also for future pathogen outbreaks. There are various research efforts in this domain, although, a need still exists for a comprehensive topic-wise analysis of tweets in favor of and against COVID-19 vaccines.

Objective

This study characterizes the discussion points in favor of and against COVID-19 vaccines posted on Twitter during the first year of the pandemic. The aim of this study was primarily to contrast the views expressed by both camps, their respective activity patterns, and their correlation with vaccine-related events. A further aim was to gauge the genuineness of the concerns expressed in antivax tweets.

Methods

We examined a Twitter data set containing 75 million English tweets discussing the COVID-19 vaccination from March 2020 to March 2021. We trained a stance detection algorithm using natural language processing techniques to classify tweets as antivax or provax and examined the main topics of discourse using topic modeling techniques.

Results

Provax tweets (37 million) far outnumbered antivax tweets (10 million) and focused mostly on vaccine development, whereas antivax tweets covered a wide range of topics, including opposition to vaccine mandate and concerns about safety. Although some antivax tweets included genuine concerns, there was a large amount of falsehood. Both stances discussed many of the same topics from opposite viewpoints. Memes and jokes were among the most retweeted messages. Most tweets from both stances (9,007,481/10,566,679, 85.24% antivax and 24,463,708/37,044,507, 66.03% provax tweets) came from dual-stance users who posted both provax and antivax tweets during the observation period.

Conclusions

This study is a comprehensive account of COVID-19 vaccine discourse in the English language on Twitter from March 2020 to March 2021. The broad range of discussion points covered almost the entire conversation, and their temporal dynamics revealed a significant correlation with COVID-19 vaccine–related events. We did not find any evidence of polarization and prevalence of antivax discourse over Twitter. However, targeted countering of falsehoods is important because only a small fraction of antivax discourse touched on a genuine issue. Future research should examine the role of memes and humor in driving web-based social media activity.
AB v Northwest Territories: A New Low for the Doré/Loyola Framework
Authors: Schenk Adam
Published: June 2023

Since the advent of the Canadian Charter of Rights and Freedoms in 1982, the relationship between the Charter and administrative law has been somewhat rocky. The unique nature of administrative decisions has been perceived by some jurists as requiring an unnecessarily nuanced approach to Charter issues in the administrative law context, resulting in problematic decisions untethered from jurisprudential Charter reasoning and the text of the Charter itself. The most notable of these cases are Doré v Québec and Loyola High School v Québec (Attorney General). The legacy of these decisions, sometimes referred to as the Doré/Loyola framework, regrettably established that on judicial review, administrative decisions need only demonstrate a proper balancing of implicated Charter rights or elusively-defined Charter values with relevant governmental objectives, and that these decisions will only be reviewed on a standard of reasonableness rather than correctness. The recent decision of the Northwest Territories Court of Appeal in AB v Northwest Territories (Minister of Education, Culture and Employment) (“AB”) highlights how far down a slippery slope of constitutional misinterpretation the framework has allowed the law to slide.
Toxic Epidermal Necrolysis : A Case Report in 9-Year Old Girl
Authors: Rusetiyanti Nurwestu , Damayanti RR. Vetria Sekar , Rakhmayunita Ravicka , Sugiarsih Sugiarsih
Published: June 2023

Introduction. Toxic Epidermal Necrolysis (TEN) is a acute and severe reactions of skin and mucosa that can lead to serious clinical outcomes and morbidity. TEN is considered to be rare in children and usually has a fatal outcome due to sepsis.Case. 9-year old girl, went to Universitas Gadjah Mada (UGM) Hospital with complaint of erythematous, purpuric rash, blister starting from the neck and also involving the inside of the mouth, lips and eyes, and spreading over the entire body. Three weeks before hospital admission, she received combination of drugs valproate sodium, clonazepam, phenobarbital and piracetam. Two week after, she developed skin rash and progress to develop TEN. Sodium valproate and clonazepam were discontinued, and intravenous methylprednisolone, prophylactic systemic antibiotics, intravenous immunoglobulin (IVIG), intravenous fluid supplement, antipyretic, special wound care at semi sterile room, and supportive medical care fro TEN were administered. She was discharged from hospital in a stable, good condition.Discussion. This case suggests that sodium valproate contributed to the development of TEN. Appropriate case management will give excellent result, and reduce long-term complications.
Identification of Waste Handling Compliance of Sharp Objects at Universitas Gadjah Mada Academic Hospital Yogyakarta
Authors: Nugraheni Timuryani
Published: June 2023

Background: Health care processes that occur in the hospital cannot be separated from factor control and prevention of infection. One of the biggest challenges of the current hospital is to be able to reduce the number of infections that occur during the delivery of health services in progress.Objective: This research aimed to identify compliance with the infection control policy concerning health workers and sharp objects in order to prevent spread of infection and to decide upon the chain of infection transmission in Universitas Gadjah Mada Academic Hospital, Yogyakarta, Indonesia.Design:  This research was a descriptive analytic study. Data were collected by observation methods using a survey instrument in the form of a check list. The processing of data involved factor analysis and narratives in descriptive form with percentages and tables.The study population involved total sampling of 30 percent of the total measures undertaken by syringe healthcare workers who work in the ER, Intensive Care Installation, Operation Room and Midwifery Care Lounge. The sample set included 40 activities. The Observation Sheet was based on the Guide PPI from the 2011 Nurses Association of Infection Prevention and Control.Results: The incidence of needle stick during January - April 2015 increased significantly to 4 events. Rate of compliance officers in managing sharps waste was: 67.5% with 25 % of corporate compliance officers not doing recapping or closure of needles (minimum scale). A sharp object was not given to others as much as 82.5% (Medium scale). When intending to give a sharp object to another person then the container was used as much as 57.5% (minimum scale). Sharps waste were put into a special puncture resistant and waterproof box 97.5% (scale of Good). Safety box 3/4 full of sharps waste was sealed or sealed and thrown into the garbage storage area as much as 75% (minimum scale).Conclusions: The availability of adequate infrastructure, e.g. Safe Injecting SPO, SPO sharps waste management, availability of containers for storing syringe when it will be handed over to another officer, and the availability of adequate safety box needs to be improved. Workers should strictly follow the NSI (Needle Stick Injury) prevention and control program and execute compliance based on SPO guided by the universal precautions and hierarchical control policy.
Correlation of Volume and Intracerebral Site with Hemorrhagic Stroke Mortality Based on CT Scan
Authors: Rizal Andi , Faisal Arif , Dwidanarti Sri Retna
Published: June 2023

Background: Intracerebral hemorrhage is a bleeding in the brain’s parenchyma that can extend into the ventricles, and in rare cases into the subarachnoid area. The effects of hemorrhage volume are from mild to severe clinical symptoms due to the increased intracranial pressure. Head CT scan is used to rule out other causes than stroke.Objective: This study aimed to determine the correlation of intracerebral hemorrhage volume and hemorrhage site with mortality of hemorrhagic stroke patients based on head CT scan tests.Design: This research used analytic observational methods to conduct a positive correlation assessment of volume and hemorrhage site with mortality in intracerebral hemorrhagic stroke patients. The study used a cross-sectional design with retrospective data. Data were assessed from 55 cases consisting of 29 men and 26 women.Results: The commonest hemorrhage was found in 24 cases (43.6%) in ganglia basalis, 15 cases (27.3%) in lobus parietalis and 8 cases (14.5%) in pons. Blood volume decreased to 25 cc in 35 cases (63.6%), 25-50 cc in 13 cases (23.6%), and decreased to more than 50 cc in 7 cases (12.7%). Correlations of contingency coefficient tests between mortality and hemorrhage site in lobar were (r=0.049, p=0.714), in deep artery territories (r=0.170, p=0.200) and in brain stem (r=0.298, p=0.020). Meanwhile, correlations between mortality and decreased blood volume to 25 cc were (r=0.589, p=0.000), in 25-50 cc (r=0.406, p=0.001) and for blood volume more than 50 cc (r=0.437, p=0.000).Conclusions: There was positive correlation between mortality and hemorrhage site in brain stem while in lobar and in deep artery territories there was no correlation with mortality and hemorrhage site. There were positive correlations between intracerebral hemorrhage volume and mortality with moderate correlation strength.
Information System for Prevention of National Healthcare Insurance Fraud Among Inpatients of Advanced Referral Health Services
Authors: Santoso Budi , Hendrartini Yulita , Djoko Rianto Bambang Udji , Trisnantoro Laksono
Published: June 2023

Background: The National Health Insurance (JKN) was started from January 1st, 2014, however every year there was a deficit between the income of the Social Security Administrator Healthcare (BPJS Kesehatan) and the money paid to healthcare facilities. One of the causes was the potential for JKN fraud in inpatient services at advanced referral health facilities (FKRTL). As a response, the Ministry of Health, the Corruption Eradication Commission (KPK) and other JKN stakeholders currently are developing a JKN fraud prevention, early detection, investigation and action system.Objective: This research aimed to analyze the implementation of the new information system for potential JKN fraud prevention and detection in inpatient services for JKN participants in RSUP Dr. Soeradji Tirtonegoro as an example of FKRTL.Design: This study used cross-sectional methods in assessing JKN fraud in single episodes of patient care by using JKN fraud indicators in the information system. We identified potential JKN fraud during April-July 2017 from JKN claim data. Reliability of information system was assessed by HOT-Fit research questionnaire (Human Organization Technology and Benefit) and Stata® software.Results: The data shown there was a significant decrease in potential JKN fraud conducted by FKRTL between April-July 2017: in April 14 findings, May 8 findings, June 1 findings, and July there were no findings. Prevention and early detection of potential JKN fraud among hospitalized JKN participants were conducted effectively by using an information system that contains indicators of JKN fraud. Reliability analysis of information system on the patient administration officers (TURP), BPJS Kesehatan officers and hospital internal verification officers resulted in alpha Cronbach value of > 0.8.Conclusions: The results show that the information system is reliable to prevent and early detect potential JKN fraud in inpatient services for JKN participants in FKRTL. Information system is effective and reliable for prevention and early detection potential National Health Insurance fraud in service of inpatient advanced referral health services.
FORMULASI NUTRISI ENTERAL BERBASIS TEPUNG EDAMAME UNTUK ALTERNATIF DIET CAIR PASIEN STROKE
Authors: Elvizahro Leiyla , Purwandari Aprillia Dewi Arum Nur , Prastiwi Riska Yunida , Putri Syari Ernawati , Majid Vivi Meiliza
Published: June 2023

Background: At UGM Academic Hospital, the liquid diet that has been given to stroke patients is a high-energy, high-protein and low-sodium enteral commercial formula. Commercial enteral formula has a relatively expensive price so we need a ready-made enteral product at a more affordable price. Hospitals can utilize potential ingredients to produce ready-to-use enteral formulas, one of which is edamame bean flour. Objective: Producing edamame flour-based enteral nutrition products that can be organoleptically acceptable, meet nutritional requirements, and meet the physical requirements of enteral nutrition for stroke patients. Design: Laboratory experimental research with a Completely Randomized Design with four research stage: 1) Making and testing the nutritional value of edamame flour, 2) Formulation of edamame flour-based enteral nutrition, 3) Testing of organoleptic quality, physical properties, and nutritional value and calculating the cost of enteral nutrition edamame flour based, 4) Determination of the selected formula. Results: Edamame flour produced in this study had the highest percentage of nutrient content in the form of protein (31.5%) and antioxidant activity of 69.75%. Based on the calculation of nutritional value, determined 3 formulas, namely formula A (comparison of edamame flour: 1: 4 skim milk), formula B (2: 3), and formula C (1: 2). From the results of testing the nutritional value, physical properties, cost, and level of preference, formula A is determined as the chosen formula. Formula A has a protein content of 21.88%; energy content of 332.54 Kcal / 100 g; viscosity 8.6 cP; osmolality 436 mOsmol / Kg water; and most preferred panelists in terms of taste. Conclusions: Edamame flour formula can be used as an alternative liquid diet for stroke patients with energy and protein content such as commercial stroke formulas.
ANALISIS TEKSTUR DAN VISKOSITAS BAHAN PENGENTAL LOKAL SEBAGAI PENGGANTI FOOD THICKENER KOMERSIAL UNTUK PASIEN GANGGUAN MENELAN
Authors: Adistyawan Guritno , Dinia Sari Pratiwi , Elvizahro Leiyla , Dewi Arum Nur P Aprillia
Published: June 2023

ABSTRACT  Background: Management of cases of difficulty swallowing in Indonesia has so far only used standardized forms of hospital food consisting of ordinary foods, soft foods, chopped foods, filtered foods and liquid foods. In developed countries, the use of commercial food thickener is commonly used for cases of swallowing disorders. Commercial food thickener products are difficult to obtain in Indonesia and the price is quite expensive so that substitute products that are derived from local and cheap food are needed.It is necessary to develop an alternative formulation of food thickener made from local which is easily obtained and cheaper in price as an alternative solution to the problem of eating difficulties. Some ingredients that have properties as a food thickener are glucomannan porang and xanthan gum. Porang glucomannan has a high fiber content while xanthan gum has high viscosity in low concentration. Objective: The purpose of this study was to determine the texture and viscosity of local thickener food in accordance with the consistency of commercial food thickener as a gold standard. Design: eksperimental laboratorium research which is held at the Nutrition Department in UGM Academic Hospital on June until November 2019, with the research steps are: 1) Make a standard gold solution of 6 grams of commercial food thickener 2) Measuring the texture and viscosity of a standard gold solution used as a comparison with other products 3) Conducting subjective and objective tests of local ingredients, namely glucomannan porang and xanthan gum. Results: From the research conducted in the laboratory by using the RVA method, all 4 flour (cornstarch, sago flour, arrowroot flour, tapioca flour and porang glucomannan flour) showed a viscosity close to the thickness of commercial food thickener. The advantage of glukomanan flour is that after the maximum viscosity value is reached, the viscosity does not change with an increase in temperature or when the temperature decreases. Conclusions: Porang glucomannan has a texture similar to commercial food thickener (gold standard), the viscosity of porang glucomannan tends to be stable with changes in temperature and when the temperature decreases so that it can be used as an alternative food thickener for dysphagia patients.
Differences in Satisfaction Level between Subsidised JKN Patients and Non-Subsidised JKN Patients: A Case Study in a Hospital in Bantul with Quantitative Analysis Approach
Authors: Pratama Yanasta Yudo , Hidayat Muhammad Syamsu , Marwati Tri Ani , Handayani Lina
Published: June 2023

ABSTRACTIntroduction: The National Health Insurance (JKN) organized by BPJS is a guarantee in the form of health protection so that participants get the benefits of health checks and protection in meeting basic health needs given to everyone. Measuring the level of patient satisfaction is needed to determine the level of service provided by a service provider. To identify differences in the satisfaction of JKN class 3 PBI patients and JKN class 3 non PBI patients who received health services at the place research.Materials and Methods: This study used an analytical observational research design with a cross sectional method through a Quantitative Method approach. Data obtained by using questionnaires and interviews with respondents. The level of patient satisfaction was analyzed using GAP scores, CSI, and Independent Samples T Test.Results: The results of the GAP score indicate that JKN class 3 PBI patients have the lowest GAP score on the reliability dimension, which is -0.1733 and the highest GAP score on the assurance dimension with a score of -0.0875. Meanwhile, JKN class 3 non-PBI patients had the lowest score on the tangibles dimension with -0.1955 and the highest on the reliability dimension with -0.1711. JKN class 3 PBI patients had a CSI score of 69.81% and JKN class 3 non-PBI patients had 66.938%. If statistically tested, there is a significant difference between JKN class 3 PBI patients and JKN class 3 non-PBI patients with p value < 0.05.Conclusion: From the results of the analysis, at the placed research patients are generally satisfied with the services provided. JKN class 3 PBI patients feel more satisfied than JKN class 3 non PBI patients.
Global South Perspective on the Threat to Multilateralism in G20 Post-Russia’s Invasion of Ukraine
Authors: Fadhlia Maudy Noor , Bimantara Azza
Published: June 2023

The G20 is set up to foster cooperation among states while sharing common principles and values. Even though it was first created to handle the global financial crisis, G20 has become a big multilateral forum covering other strategic developmental issues. At the beginning of this year, Russia's invasion of Ukraine came unexpectedly and created commotion among the G20 members. Some members assume it threatens multilateralism in G20 since Russia ignores international law. This paper uses a qualitative approach through a case study, collects the data from a literature review, and looks at different dimensions of multilateralism. Furthermore, the discussion will focus on the perspective of the Global South regarding the multilateralism crisis by overviewing the characteristics of multilateralism in crisis. The result of this paper indicates that the division among the West, Russia, China, and other members showed that the consensus and compliance in G20 no longer exist. It is considered a sign of the deficit of multilateralism where Russia and the West challenged and then pressured the multilateral system. On the other hand, most Global South countries took a different perspective and stance when the West and its allies heavily condemned Russia. While the other countries busily try to expel Russia from G20, the Global South representative countries remain neutral to maintain their relationship with the superpowers. The different perspectives and actions among the G20 members emphasize the crisis of multilateralism that reflects a battle of narratives.
Pengembangan Purwarupa Laboratorium Virtual Berbasis VMWare dengan Terraform
Authors: Kusuma Michael Putra , Rosyid Nur Rohman
Published: June 2023

Pada tahun-tahun terakhir, Laboratorium Virtual telah semakin marak digunakan oleh organisasi di seluruh dunia sebagai media pembelajaran dan tempat melatih skill di bidang teknologi informasi dengan menyediakan virtual machine lab yang dapat dibuat dan diberhentikan menggunakan tombol yang terdapat di website pembelajaran. Dengan adanya purwarupa Laboratorium Virtual yang menerapkan Infrasructure as Code, maka hal tersebut akan memudahkan Administrator infrastruktur dalam mengelola infrastruktur virtual. Diperlukannya sebuah antarmuka berbasis website yang dapat melakukan pembuatan virtual machine lab, melihat status virtual machine lab yang dibuat serta menghapus virtual machine lab yang telah dibuat jika sudah tidak ingin menggunakan virtual machine lab tersebut. Pengembangan purwarupa website Laboratorium Virtual ini mengunakan PHP sebagai server side scripting untuk menjalankan script dari tiap fiturnya. Infratruktur as Code pada purwarupa ini berfungsi sebagai otomatisasi pengelolaan dan penyediaan virtual machine lab pada VMWare ESXi menggunakan Terraform. Sebelum dapat mengakses website tersebut, user yang terdaftar di database diharuskan untuk login terlebih dahulu sehingga dapat diarahkan ke folder yang telah disediakan untuk masing-masing user. Harapan dengan adanya aplikasi website ini adalah dapat memudahkan Administrator infrastruktur laboratorium dalam melakukan manajemen virtual machine lab, sehingga tidak perlu repot-repot lagi untuk melakukan konfigurasi tiap virtual machine secara manual bagi tiap user.
L2 ENGLISH ARTICLE SUPPLIANCE AMONG TERTIARY LEVEL STUDENTS: THE IMPACT OF SPECIFICITY
Authors: Veličković Marta
Published: June 2023

The aim of this paper was to determine the role of specificity in the English article suppliance of L1 Serbian speakers. Its impact on the suppliance of the definite article (the), the indefinite article (a/an), and the zero article (Ɵ) was determined based on a 40-item questionnaire. The items were classified into four groups defined by the combinations of two semantic features: [±specific] and [±definite]. Differences in article suppliance were studied between a group of English and non-English language majors in order to take into account the level of L2 proficiency. The population of L1 Serbian/L2 English speakers was chosen since Serbian is an articleless language and is, unlike English, considered to code specificity. The results indicated statistically significant differences between the participants in terms of correct article suppliance and L2 proficiency in favor of the English language majors. However, no impact of specificity on article suppliance was noted for either group of participants.
IDENTIFYING THE DIMENSIONS OF THE SCHOOL CLIMATE FROM THE PERSPECTIVE OF PRIMARY SCHOOL STUDENTS
Authors: Jevtić Bisera , Milošević Danijela
Published: June 2023

The school climate is a significant factor in the development of students’ cognitive, emotional and social competencies. Starting from the fact that the quality of educational work largely depends on the school climate, the aim of this research was to identify the factors influencing the development of a positive school climate, and to determine the differences in the perception of its dimensions in relation to gender and student success. The sample for this research consisted of 216 primary school students in the Republic of Serbia. An instrument composed of 43 items was used in the research. Factor analysis identified 6 factors that affect the school climate: support and consistency in the work of teachers, student autonomy, the academic support of teachers, negative peer relationships, disciplinary rigor and collaborative peer learning. The students’ perception of the dimensions of the school climate was influenced by school success and the gender of the students. This research offers a comprehensive theoretical perspective for all researchers for whom the field of school climate is at the center of interest, as well as potential solutions in terms of improvement in educational practice.