bluuebunny/crossref_metadata_2025 huggingface dataset:
Penggunaan Antibiotik pada Terapi Demam Tifoid Anak di RSAB Harapan Kita
Authors: Adisasmito Amar W
Published: January 2017

Latar belakang. Insidens demam tifoid di Indonesia cukup tinggi (>100 kasus per100.000 populasi per tahun). Insidens pada anak usia 3-6 tahun adalah 1307 per 100.000populasi per tahun, dan 1172 pada usia 7-19 tahun. Chloramphenicol sampai saat inimasih merupakan obat pilihan lini pertama untuk terapi demam tifoid pada anak.Antibiotik lain yang dipergunakan untuk terapi demam tifoid anak adalah cotrimoxazole,cefixime dan ceftriaxone.Tujuan penelitian. Untuk mengevaluasi aspek pemberian antibiotik berdasar berbagaisituasi klinis pada terapi demam tifoid anak di ruang Rawat Inap Anak, DepartemenAnak, RSAB Harapan Kita, Jakarta.Metoda. Penelitian dengan desain deskriptif-retrospektif telah dilakukan di DepartemenAnak, RSAB Harapan Kita, Jakarta dari 1 Januari hingga 31 Desember 2004 Kriteriainklusi adalah pasien berusia antara 1 bulan sampai 18 tahun, gejala klinis sesuai demamtifoid, dan diagnosis pasti berdasar hasil biakan darah dengan metoda Bac-tect, positifSalmonella typhi. Data diperoleh dari rekapan laboratorium Mikrobiologi dan rekammedik pasien. Korelasi antara ketepatan dosis antibiotik dan lama rawat atau length ofstay (LOS) dievaluasi menggunakan program Excell.Hasil. Sebanyak 31 pasien memenuhi kriteria inklusi. Dari 31 pasien yang ditelitiditemukan bahwa pasien demam tifoid terbanyak adalah usia 6-10 tahun, diikuti usia 1– 5 tahun. Sensitifitas dan spesifisitas uji Widal terhadap uji Bac-tect rendah atau tidakmemadai, sehingga uji Widal disini tampaknya bukanlah uji yang baik dalam menegakkandiagnosis demam tifoid. Komplikasi terjadi pada 7 dari 31 pasien, terdiri dari pneumoniadan perdarahan saluran cerna. Ditemukan seluruhnya 1 kasus relaps dari 31 pasien.Tampaknya tidak ada perbedaan yang nyata antara rata-rata lama rawat dan ketepatandosis antibiotik yang diberikan.Kesimpulan. Antibiotik terbanyak yang dipakai adalah golongan chloramphenicol danceftriaxone intravena. Tidak ada hubungan yang nyata antara pemberian antibiotikdengan dosis kurang terhadap lama rawat pasien, tetapi tentunya masih banyak faktorlain yang dapat mempengaruhinya.
Penyakit Respiratorik pada Anak dengan HIV
Authors: Yani Finny Fitry , Akib Arwin AP , Supriyatno Bambang , Setyanto Darmawan B. , Kurniati Nia , Kaswandani Nastiti
Published: January 2017

Latar belakang. Kejadian AIDS pada anak meningkat seiring dengan peningkatan kasusdewasa. Gejala dan manifestasi klinis sering tidak khas, sehingga menyebabkanunderdiagnosis. Anak HIV sering datang dengan keluhan yang berasal dari infeksioportunistik, bahkan infeksi oportunistik banyak ditemukan sebagai penyebab kematian.Salah satu infeksi oportunistik yang sering terjadi adalah infeksi respiratorik.Tujuan penelitian. Penelitian ini bertujuan untuk melihat pola penyakit respiratorikpada anak HIV yang dirawat di Bagian Ilmu Kesehatan RS Dr. Cipto Mangunkusumo(RSCM), Jakarta.Metoda. Data berasal dari rekam medis anak HIV tahun 2002-2005. Penelitiandilakukan dengan desain potong lintang. Kriteria inklusi adalah anak usia 0-13 tahun,dengan HIV positif dan menderita penyakit respiratorik. Data yang dicatat meliputiumur, jenis kelamin, faktor risiko, status gizi, parut BCG, diameter uji tuberkulin, riwayatkontak dengan pasien tuberkolosis, kategori HIV, diagnosis penyakit respiratorik,outcome. Data klinis khusus meliputi batuk kronik berulang, demam lama, sesak nafas,laboratorium rutin, foto torak, dan kadar CD4, PCR.Hasil. Sejak Januari 2002-Desember 2005, telah dirawat 85 anak yang terinfeksi HIV,dengan 13 orang (15,2%) di antaranya meninggal. Tiga belas orang (13/35) didiagnosisHIV berdasarkan serologi dan PCR, 24/35 hanya dengan serologi, dan 1/35 orang denganPCR. Sebanyak 38 (44,7%) orang menderita infeksi respiratorik dengan pola penyakit: TB47,3%, pneumonia 44,7%, pneumocytis corinii pneumonia (PCP) 13,1%. Pada penelitianini, didapatkan bahwa 3/38 (7,8%) anak HIV dengan penyakit paru meninggal karenapneumonia berat, dengan 2/3 di antaranya pada kelompok umur 1-5 tahun. Penyebabkematian lainnya adalah PCP 2/38 pasien (5,2%), dan tersangka sepsis pada 2 pasien (5,2%).Kesimpulan. Pada anak HIV, TB merupakan penyakit respiratorik terbanyak, diikutipneumonia, sedangkan penyebab kematian terbanyak adalah pneumonia. Penyakitrespiratorik pada anak HIV dapat menjadi pembuka jalan untuk diagnosis anak HIV.
Refluks Vesiko Ureter
Authors: Kompiyang Indriyani Sang Ayu , Ketut Suarta
Published: January 2017

Refluks vesiko ureter (RVU) merupakan kelainan traktus urinarius yang biasa terjadipada anak. Kelainan ini seringkali didiagnosis sebagai penyerta pada anak dengan infeksisaluran kemih (ISK), meskipun terjadi peningkatan jumlah kasus yang didiagnosis saatlahir melalui pemeriksaan sonografi terdapat pelvo-kaleaktasis atau hidronefrosis.Kejadian RVU dapat menyebabkan terjadinya parut ginjal disertai hipertensi yang dapatberlanjut menjadi gagal ginjal kronik. Diagnosis dini melalui anamnesis, pemeriksaanfisik, laboratorium dan radiologi khususnya voiding cystourethrogram (VCUG) harusdilakukan untuk menentukan tata laksana yang sesuai. Sebagian besar pasien mendapatpengobatan medikamentosa tanpa memerlukan tindakan pembedahan.
Perbedaan Kecepatan Kesembuhan Anak Gizi Buruk yang Diberi Modisco Susu Formula dan Modisco Susu Formula Elemental Di RSU dr. Soetomo Surabaya
Authors: Irawan Roedi
Published: January 2017

Latar belakang. Dalam tata laksana kasus gizi buruk yang dirawat di rumah sakitmemerlukan nutrisi yang terbaik dalam mempercepat kesembuhannya terhadap penyakitutama maupun upaya dalam memperbaiki status gizi. Oleh karena itu sampai saat inimasih dicari dan diujicobakan beberapa nutrisi yang tepat dan terbaik pada anak giziburuk.Tujuan. Penelitian ini bertujuan mempelajari perbedaan kecepatan kesembuhan padaanak gizi buruk yang diberi modisco susu formula dan modisco susu formula elemental.Metoda. Pengambilan sampel secara acak buta ganda dengan uji eksperimental. Kriteriainklusi yaitu anak umur 1–3 tahun dengan status gizi buruk dan menderita penyakitinfeksi. Subyek penelitian diambil dari 112 populasi anak gizi buruk yang menderitaberbagai macam penyakit infeksi sebagai penyakit primer.Hasil. Didapatkan 49 anak diantaranya yang masuk kriteria inklusi, kemudian dibagidalam 2 kelompok: 27 anak diberi modisco susu formula dan 22 anak diberi modiscosusu formula elemental. Terdapat perbedaan bermakna antara berat badan sebelum dansesudah penelitian pada kedua kelompok (P<0,05). Perbedaan bermakna pada nilai Zskorberat badan terhadap tinggi badan (BB/TB) antara kelompok yang diberi modiscosusu formula dan modisco susu formula elemental (P<0,05).Kesimpulan. Kelompok yang diberi modisco susu formula elemental menunjukkanpenyembuhan yang lebih cepat dibanding kelompok yang diberi modisco susu formula.
Pengenalan Acquired Immunodeficiency Syndrome pada Pasien Anak Ditinjau dari Bidang Kedokteran Gigi Anak
Authors: Octiara Essie , Cahyati Miftakhul , Aulia Virmala Indah
Published: January 2017

Acquired Immunodeficiency Syndrome (AIDS) merupakan kumpulan gejala penyakityang disebabkan infeksi Human Immunodeficiency Virus (HIV). 1 Di dunia pada tahun2002 sebanyak 3,2 juta anak telah terinfeksi HIV. Penularan HIV/AIDS pada anakdapat terjadi antara lain melalui tranfusi darah serta oleh ibu yang terinfeksi kepada bayiyang dikandungnya. Manifestasi pada rongga mulut merupakan salah satu gejala yangpertama kali timbul dan paling dapat dipercaya akan adanya infeksi HIV pada anak, danhal ini penting dalam mendiagnosis awal infeksi HIV serta dalam memberikan upayaintervensi dini. Manifestasi oral pada pasien anak dengan infeksi HIV berupa infeksijamur, virus, bakteri, neoplasma ataupun lesi idiopatik. Peran dokter gigi anak dalampreventif kesehatan mulut bagi pasien anak HIV antara lain melakukan supervisi semuapemberian makanan dengan botol, managemen medikasi yang kariogenik, sertamelakukan sealant dan pemberian fluor secara sistemik dan topikal.
Gambaran Epidemiologi Infeksi Nosokomial Aliran Darah pada Bayi Baru Lahir
Authors: Alatas Fatima Safira , Satari Hindra Irawan , Chair Imral , Rohsiswatmo Rinawati , Munasir Zakiudin , Windiastuti Endang
Published: January 2017

Latar belakang. Infeksi nosokomial (IN) pada bayi baru lahir sampai saat ini masih merupakan masalahserius di setiap rumah sakit karena dapat meningkatkan morbiditas, mortalitas, lama dan biaya rumahsakit serta risiko kecacatan pada bayi yang terinfeksi.Tujuan penelitian. Mengetahui gambaran epidemiologi, pola kuman dan resistensi mikroorganisme penyebabIN aliran darah (INAD) pada bayi baru lahir di ruang rawat Divisi Perinatologi Departemen IKA RSCM.Metode. Penelitian ini merupakan penelitian prospektif deskriptif dengan desain studi seksi silang diruang rawat Divisi Perinatologi IKA RSCM.Hasil. Insidens INAD pada bayi baru lahir yaitu 34,8 infeksi per 100 pasien baru atau 50 infeksi per 1000kelahiran dengan case fatality rate 27,4% dari seluruh kasus INAD (2) Infeksi bakteri gram negatif (GN)merupakan bakteri terbanyak dengan kuman terbanyak Acinetobacter calcoaceticus 28,8% (3) Sensitivitasbakteri GN terhadap antibiotika lini pertama dan kedua rendah sedangkan lini ketiga yaitu meropenemdan lini keempat yaitu siprofloksasin cukup baik yaitu masing-masing 66,67 – 100%.Kesimpulan. Angka kejadian dan case fatality rate INAD pada bayi baru lahir masih cukup tinggi. Infeksibakteri gram negatif masih merupakan penyebab terbanyak
Pemantauan Tumbuh Kembang Anak dengan Sindrom Down
Authors: Kawanto Frieda Handayani , Soedjatmiko Soedjatmiko
Published: January 2017

Sindrom Down (SD) adalah kelainan genetik yang paling sering ditemukan dan berhubungan denganretardasi mental. Kelainan yang terjadi disebabkan oleh adanya kelebihan materi genetik kromosom 21.Karakteristik fisis anak dengan SD cukup jelas sehingga para tenaga kesehatan yang mengadakan kontakawal dengan neonatus, termasuk dokter ahli kebidanan dan kandungan, perawat kamar bersalin, dandokter umum, dapat mengenali kelainan ini dengan relatif mudah. Anak dengan SD memiliki berbagaimasalah kesehatan dan tumbuh kembang yang tak jarang cukup kompleks, maka skrining pra dan pascanatal, intervensi dini, dan pemantauan tumbuh kembang yang terus-menerus perlu dilakukan agar anakdengan SD dapat memiliki kualitas hidup yang lebih baik. Tata laksana medis, dukungan keluarga,pendidikan, dan pelatihan khusus dapat meningkatkan kemampuan anak dengan SD secara bermakna danmenjembatani transisi menuju kedewasaan.
Perbedaan Tingkat Kualitas Hidup Anak dengan Sindrom Nefrotik Primer Kelainan Minimal dan Bukan Kelainan Minimal Di RSUP Dr. Sardjito Yogyakarta
Authors: Simatupang Dwi Fiona , Damanik M.P. , Sadjimin Tonny
Published: January 2017

Latar belakang. Mengukur kualitas hidup anak dengan penyakit kronis memberikan gambaran efekterapi, aspek yang terganggu dan dasar pertimbangan dalam melakukan intervensi. Pengukuran kualitashidup pada anak sindrom nefrotik dan faktor-faktor yang mempengaruhinya jarang dilakukan.Tujuan. Mengetahui perbedaan tingkat kualitas hidup antara anak dengan sindrom nefrotik primer kelainanminimal dan bukan kelainan minimal.Metode. Penelitian dilakukan secara kohort dengan responden 70 anak sindrom nefrotik berusia 6-15tahun yang dirawat di RSUP Dr. Sardjito tahun 2000-2005. Pengukuran menggunakan kuisioner kualitashidup TACQOL (formulir anak dan orang tua). Kuisioner diisi melalui wawancara langsung dengan anakdan orang tua responden.Hasil. Terdapat hubungan bermakna pada tingkat kualitas hidup antara anak dengan sindrom nefrotikprimer kelainan minimal dan bukan kelainan minimal menurut persepsi orang tua (p=0,001), tetapi tidakmenurut persepsi anak. Pada analisis bivariat faktor yang berhubungan dengan kualitas hidup buruk adalahjenis sindrom nefrotik bukan kelainan minimal RO 0,131 IK 95% 0,035-0,497. Terdapat hubungan yangbermakna antara pola asuh orang tua dengan jenis morfologi sindrom nefrotik (p=0,042). Di antara 7aspek kualitas hidup yang diukur, nilai tertinggi terlihat pada fungsi otonom dan motorik. Nilai terendahmenurut persepsi orang tua dan anak ialah fungsi sosial.Kesimpulan. Terdapat perbedaan tingkat kualitas hidup antara anak dengan sindrom nefrotik primer kelainanminimal dan bukan kelainan minimal menurut persepsi orang tua. Perbedaan morfologi, pola asuh orang tuamerupakan faktor yang mempengaruhi tingkat kualitas hidup anak dengan sindrom nefrotik dan memilikimasalah dengan fungsi sosial menurut persepsi orang tua dan anak.
Efektivitas dan Keamanan Kombinasi Terfenadin dan Pseudoefedrin pada Anak Rinitis Alergika
Authors: Nahrawi Nahrawi , Munasir Zakiudin , Latief Abdul
Published: January 2017

Latar belakang. Kombinasi terfenadin dan pseudoefedrin telah terbukti efektif mengatasi rinitis alergikatetapi sejak diketahui efek kardiotoksik terfenadin, diperlukan penilaian lanjutan keamanannya padaanak.Tujuan. Mengetahui tingkat keamanan dan efektivitas kombinasi terfenadin dan pseudoefedrin padaanak rinitis alergika.Metode. Penelitian open trial, tanpa kontrol dengan desain before and after. Pasien rinitis alergika denganelektrokardiografi (EKG) normal, diberikan pengobatan kombinasi terfenadin dan pseudoefedrin 5 hari,kemudian penilaian gejala klinis, reaksi simpang dan EKG ulang pasca pengobatan.Hasil.: Lima puluh empat pasien (70,1 %) dengan skala penilaian pengobatan baik, 20 (26%) denganskala sangat baik, dan tidak ditemukan perburukan. Tidak ditemukan perbedaan interval Q-T dan Q-Tcsebelum (0,33 detik dan 0,41 detik) dan sesudah pengobatan (0,33 detik dan 0,41 detik). Pada sebagianbesar pasien (94,8%) tidak dijumpai reaksi simpang.Kesimpulan. Kombinasi terfenadin dan pseudoefedrin pada anak rinitis alergika terbukti aman dan efektif.Sebagian besar pasien tidak ditemukan reaksi simpang dan tidak ditemukan dampak kardiotoksik
Faktor Risiko Sekuele Meningitis Bakterial pada Anak
Authors: Novariani Muriana , Herini Elisabeth Siti , Patria Suryono Yudha
Published: January 2017

Latar belakang. Mortalitas akibat meningitis bakterial menurun dengan ditemukan antibotik yang potendan penanganan yang baik pada saat pasien kritis. Walaupun demikian, sekuele akibat meningitis bakterialmasih tinggi, sekitar 50%-65% di negara berkembang.Tujuan. Mengetahui faktor risiko yang terkait dengan sekuele pada pasien meningitis bakterial yangbertahan hidup.Metode. Penelitian kasus kontrol dilakukan di RSUP Dr. Sardjito, RSUD Banyumas dan RSU SuradjiTirtonegoro Klaten. Kasus adalah pasien yang terdiagnosis meningitis bakterial pada tahun 2003 – 2006yang hidup dengan sekuele. Kontrol adalah pasien meningitis bakterial yang hidup tanpa sekuele. Datadiambil dari catatan medis, luaran ditetapkan setelah 6 bulan.Hasil. Terdapat 78 pasien yang memenuhi kriteria inklusi. Hasil analisis multivariat menunjukkan bahwafaktor risiko yang terkait dengan meningitis bakterial adalah kejang >30 menit saat masuk rumah sakit(OR 4,29; IK 95% 1,38–12,99), PCS (Pediatrics Coma Scale) <8 (OR 3,76 ; IK 95% 1,15-12,28), dankejang yang tidak terkontrol >72 jam (OR 5,24 ; IK 95% 1,49–18,43). Onset - gejala >48 jam mempunyaiOR 2,43 (IK 95% 0,73 – 8,13).Kesimpulan. Kejang >30 menit saat masuk rumah sakit, PCS <8, dan kejang yang tidak terkontrol >72 jammerupakan faktor risiko yang indipenden untuk menimbulkan sekuele.
Repositioning Pacific Arts: Artists, Objects, Histories: Proceedings of the VII International Symposium of the Pacific Arts Association, Christchurch, New Zealand (Allen and Waite, eds.)
Authors: Lythberg Billie
Published: January 2017

This work is a book review considering the title Repositioning Pacific Arts: Artists, Objects, Histories: Proceedings of the VII International Symposium of the Pacific Arts Association, Christchurch, New Zealand edited by Anne E. Allen and Deborah B. Waite.
Tōkaidō Texts and Tales: Tōkaidō gojūsan tsui by Kuniyoshi, Hiroshige, and Kunisada (Marks, ed.)
Authors: Foster Michael Dylan
Published: January 2017

This work is a book review considering the title Tōkaidō Texts and Tales: Tōkaidō gojūsan tsui by Kuniyoshi, Hiroshige, and Kunisada edited by Andreas Marks
Hubbell Trading Post: Trade, Tourism, and the Navajo Southwest (Cottam)
Authors: Stiver Louise
Published: January 2017

This work is a book review considering the title Hubbell Trading Post: Trade, Tourism, and the Navajo Southwest by Erica Cottam.
Incorporation of β-actin loading control into zymography
Authors: Govindasamy Natasha , Yan MengJie , Jurasz Paul
Published: January 2017

Gelatin zymography and immunoblot are widely used gel electrophoresis techniques to study matrix metalloproteinases-2 and -9. Each method has its advantages and disadvantages. Zymography is exquisitely sensitive but offers no loading control to ensure equal sample loading. Immunoblot is 100–1000-fold less sensitive, but allows for the probing of a sample loading control such as β-actin to ensure accurate protein loading. In this report, we describe two simple protocols that combine gelatin zymography to study MMP-2 and -9 levels with an in-gel β-actin immunoblot loading control, thus combining sensitivity and accuracy in a single assay. The protocols incorporate the loading of molecular weight markers to demarcate MMP-2/-9 from the β-actin. The first protocol utilizes the overlay of a 10% zymography gel over a 5% Tris-Glycine separating gel from which the β-actin is transferred. The second protocol involves the direct transfer of the β-actin from a single 10% zymography gel.
Evaluation of Antimicrobial-Treated Fabric Properties
Authors: Lamba Nina M. , Herson Diane S. , Jindani Rahim , King Martin W.
Published: January 2017

New antimicrobial textile finishes with enhanced action against microbes are needed for improved protection in critical applications, including hospital infection control and biodefense. This study compares fabric treated with a novel quaternary ammonium compound-based antimicrobial treatment with untreated fabric, using a new method for determining the antimicrobial efficacy of fabrics and textiles. The effects of contact temperature, contact time, and bacterial load were demonstrated. The lowest concentrations of bacterial cells were killed very quickly. Increasing contact time resulted in inactivation of larger numbers of cells, as did elevating temperature from 24 °C to 37 °C. Important physical properties of the fabrics were retained. The simplicity, and good reproducibility, of the test procedure supports its use for the rapid screening and assessment of fabric specimens for antimicrobial activity.
Inkjet Printing of Linen Fabrics Pretreated with Atmospheric Plasma and Various Print Pastes
Authors: Özgüney Arif Taner , Bozacι Ebru , Demir Aslι , Özdoğan Esen
Published: January 2017

In this study, linen fabrics were inkjet printed with reactive dyes after air argon plasma treatments. Sodium alginate (ALG), carboxymethlycellulose (CMC), chitosan (CHT), ALG+CHT, CMC+CHT, and their combinations, were used as pretreatment print pastes prior to plasma pretreatment. The color yield and the fastness properties of the printed fabrics were evaluated. The CMC+CHT pretreatment print paste gave the best color yield with or without plasma pretreatment. Colorfastness values were not affected by the type of pretreatment print paste. However, plasma pretreatment slightly improved the colorfastness.
A Nonlocal Operator Breaking the Keller–Osserman Condition
Authors: Ferreira Raúl , Pérez-Llanos Mayte
Published: January 2017

This work is concerned about the existence of solutions to the nonlocal semilinear problem

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Automatische Workflow-Generierung für Engineering-Prozesse
Authors: Seidel Heiko , Mühlhause Mathias , Jäger Tobias , Fay Alexander , Diedrich Christian
Published: January 2017

Für das Engineering komplexer Automatisierungssysteme können IT-basierte Workflows die Anwender
unterstützen, um die eigenen Aufgaben zu bewältigen und Transparenz im Engineering-Prozess zu schaffen, da in
den kollaborativen Prozessen unterschiedliche Stakeholder miteinander interagieren. Zur IT-Unterstützung von
Engineering-Prozessen können Workflow-Management-Systeme (WfMS) verwendet werden, die gerade durch eine Integration in
CAE-Werkzeuge und damit direktem Zugriff auf deren Funktionen und Daten einen wesentlichen Mehrwert bieten. Gleichzeitig
ist bei der Nutzung von WfMS im Engineering noch keine Lösung bekannt, um flexible Prozesse workflow-gestützt zu
bearbeiten. Da die erfolgreiche Projektabwicklung auch von kundenspezifischen Wünschen abhängt, die auch Anpassungen an
die Abwicklungsprozesse bedingen können, ist die Anforderung, flexible und ad-hoc Workflows bearbeiten zu können,
essentiell im Engineering. Zur Lösung dieses Problems wird im vorliegenden Beitrag ein Konzept beschrieben sowie eine
Realisierung vorgestellt, um im WfMS während der Projektabarbeitung einen Workflow dynamisch an aktuelle Gegebenheiten
anzupassen. Das wesentliche Instrument ist dabei die abzuarbeitenden Engineering-Aktivitäten entsprechend der geänderten
Projektanforderungen automatisch zu generieren und in den laufenden Workflow zu integrieren. Ergebnis ist, dass
Projektierer die aktuell zu bearbeitenden Aktivitäten und simultan die dafür relevante Information bzw. die
benötigte Funktion im CAE-Werkzeug angeboten bekommen.
Einheitliches und durchgängiges Engineering von Steuerungslösungen für hybride Energiesysteme und -netze mittels Energie-Agenten
Authors: Wassermann Erik , Linnenberg Tobias , Törsleff Sebastian , Fay Alexander , Derksen Christian , Loose Nils , Unland Rainer , Ludwig Marcel , Stötzel Marcus , Zdrallek Markus , Heldmaier Wolfram
Published: January 2017

Im Rahmen des vom BMWi geförderten Projekts Agent.HyGrid werden vereinheitlichte Energie-Agenten als
Steuerungslösung für hybride Energiesysteme und -netze entwickelt und auf ihre Anwendbarkeit hin
untersucht. Hierbei werden sowohl vereinheitlichte Daten- und Verhaltensmodelle entwickelt als auch ein Referenz- und
Entwicklungsprozess entworfen. Mit diesem durchgehenden Entwicklungsprozess soll die Anwendung der
Energie-Agenten, angefangen von der Planungs- und Simulationsphase bis hin zum realen Einsatz im physischen
Vor-Ort-System, ermöglicht werden. Als Energie-Agent wird dabei grundsätzlich ein autonomes, dezentral
operierendes Software-System verstanden, das unabhängig von der Sparte bzw. vom Energieträger auf
mehreren Ebenen eines Energie-Verteilnetzes eingesetzt werden kann. Durch die Kombination unterschiedlicher
Energieträger sollen insbesondere volatile Energieerzeugungsanlagen, wie Windkraft- und Solaranlagen, besser ins
Energienetz integriert werden. Die Herausforderungen des Projekts liegen vor allem in der vereinheitlichten Modellierung
unterschiedlicher Energieträger und -umwandlungsanlagen sowie in der Überbrückung der Lücke zwischen
Simulation und der realen Anwendung vor Ort. Dieser Artikel stellt die bisherigen Erkenntnisse in Hinblick auf die
Anwendung des Entwicklungsprozesses und des einheitlichen Datenmodells dar.
Design and Fabrication of a Novel Compact Bandpass Filter to Improve Spurious-Free Band
Authors: Rezaee Payman , Höft Michael
Published: January 2017

In this paper, a new microstrip slow wave open loop resonator is proposed. This resonator overcomes the substantial limitation of the conventional slow wave open loop resonators, which limits the spurious-free band of those resonators. The new proposed resonator improves the spurious-free band up to 8 times of the fundamental frequency, which is 3.16 times of the conventional slow wave open loop resonators. For the proposed resonator the coupling factor and the external quality factor curves, which are the design curves of a narrowband filter, are extracted using a full wave simulator, i. e. HFSS. These curves are utilized for the design of two three-pole Chebyshev bandpass filters. One of these filters is fabricated. Simulation and measurement results are reported which are in good agreement. Designed filters provide 75 % and 83 % of footprint reduction in comparison with the conventional open loop resonator filters. Different parameters which can improve the spurious-free band are explained in the paper.
Energy Dissipation Rate in an Agitated Crucible Containing Molten Metal
Authors: Li Tao , Shimasaki Shin-ichi , Narita Shunsuke , Taniguchi Shoji
Published: January 2017

The energy dissipation rate (EDR) is an important parameter for characterizing the behavior of inclusion coagulation in agitated molten metal. To clarify the inclusion coagulation mechanism, we review previous water model studies by particularly focusing on the relation between the impeller torque and the EDR of the fluid, which indicates the ratio of energy dissipated in the viscous medium to the energy inputted by the rotating impeller. In the present study, simulations coupled with experiments were performed to determine the relation between the torque and the effective EDR for water and liquid Al in crucibles with and without baffles.
The third-time chronic myeloid leukemia in lymphoblastic crisis with ABL1 kinase mutation induced by decitabine, dexamethason combined with nilotinib and dasatinib
Authors: Wang Suli , Qiao Chun , Zhu Yu , Shen Wenyi , He Guangsheng , Li Jianyong
Published: January 2017

Blast crisis (BC) is the major remaining challenge in the management of chronic myeloid leukemia (CML). The prognosis of the BC patient who carries ABL kinase mutation is very poor. One patient, with lymphoid CML-BC third time, was detected with T315A/F359I/M244V compound mutation by direct sequencing after treatment with tyrosine kinase inhibitions three years. The patient was treated with decitabine, dexamethasone, in combination with nilotinib and dasatinib. Then this patient received a complete hematologic response and cytogenetic response after two cycles of treatment.
Structural variability in M2+ 2-hydroxyphosphonoacetate moderate proton conductors
Authors: Colodrero Rosario M. P. , Salcedo Inés R. , Bazaga-García Montse , Milla-Pérez Diego F. , Durán-Martín Jonatan D. , Losilla Enrique R. , Moreno-Real Laureano , Rius Jordi , Aranda Miguel A. G. , Demadis Konstantinos D. , Olivera-Pastor Pascual , Cabeza Aurelio
Published: January 2017

The structural variability of two series of Mg2+- and Zn2+- 2-hydroxyphosphonoacetates have been studied in the range of 25–80°C and 95% relative humidity in order to correlate the structure with the proton conductivity properties. In addition to selected previously reported 1D, 2D and 3D materials, a new compound, KZn6(OOCCH(OH)PO3)4(OH)·5H2O (KZn6-HPAA-3D), has been prepared and thoroughly characterized. The crystal structure of this solid, solved ab initio from synchrotron X-ray powder diffraction data, consists of a negatively charged 3D framework with K+ ions, as compensating counterions. It also contains water molecules filling the cavities in contrast to the potassium-free 3D anhydrous NH4Zn(OOCCH(OH)PO3) (NH4Zn-HPAA-3D). In the range of temperature studied, the 1D materials exhibit a 1D→2D solid-state transition. At 80°C and 95% RH, the 2D solids show moderate proton conductivities, between 2.1×10−5 S·cm−1 and 6.7×10−5 S·cm−1. The proton conductivity is slightly increased by ammonia adsorption up to 2.6×10−4 S·cm−1, although no ammonia intercalation was observed. As synthesized KZn6-HPAA-3D exhibits a low proton conductivity, 1.6×10−6 S·cm−1, attributed to the basic character of the framework and a low mobility of water molecules. However, this solid transforms to the 2D phase, Zn(OOCCH(OH)PO3H)·2H2O, upon exposure to dry HCl(g), which enhances the proton conductivity with respect to the as-synthesized 2D material (4.5×10−4 S·cm−1). On the other hand, NH4Zn-HPAA-3D exhibited a higher proton conductivity, 1.4×10−4 S·cm−1, than the K+ analog.
Morphology of the peritoneal cavity and pathophysiological consequences
Authors: Solass Wiebke , Struller Florian , Horvath Philipp , Königsrainer Alfred , Sipos Bence , Weinreich Frank-Jürgen
Published: January 2017

The peritoneal cavity (cavum peritonei) is incompletely divided into spaces and recessus (or fossae), which are playing an important role in health and disease. Peritoneal subspaces are determined by the parietal attachments of the abdominal organs, the ligaments and mesenteries. These include the splenorenal, the falciform, the triangular, the gastrosplenic, the phrenicocolic and the gastrocolic ligaments; the greater omentum and the lesser omentum (formed by the gastrohepatic and hepatoduodenal ligaments); the small bowel mesenterium and the mesocolon. These ligaments and mesenteries divide the peritoneal cavity into several distinct anatomic and functional regions. The supramesocolic compartment is divided into a bilateral subphrenic space and a subhepatic space continuing into the lesser sac (bursa omentalis). The inframesolic compartment is divided into a left and right region by the mesentery. The right paracolic gutter communicates with the pelvis and with the right suphrenic space. The left paracolic gutter is separated from the left subphrenic space by the phrenocolic ligament. The peritoneal space is virtual, is completely occupied by the intraabdominal organs and can only be visualized by radiological means in the presence of air (organ perforation), liquid (ascites, pus, bile, gastrointestinal fluids) or tumor invasion. Peritoneal morphology has numerous pathophysiological implications: it impacts on the propagation of intraabdominal infections, determines the spreading of peritoneal metastasis and can cause bowel volvulus. Internal hernias can arise at the junction between intraperitoneal and extraperitoneal bowel segments, in particular into the left paraduodenal recessus. Knowledge of peritoneal morphology is a precondition for developing locoregional therapeutic strategies in peritoneal disease and for effective peritoneal dialysis.
Codierte Sendesignale für die Ultraschallprüfung von Betonbauteilen
Authors: Feller Viktor , Mielentz Frank , Klewe Tim , Orglmeister Reinhold
Published: January 2017

Es wurden Untersuchungen hinsichtlich der Eignung und der praktischen Relevanz von codierten Sendesignalen als
Anregungsimpulse für die Ultraschallprüfung von Betonbauteilen durchgeführt. Anhand von synthetischen Daten werden die
theoretischen Vorteile der codierten Impulssequenzen gezeigt. Im Anschluss werden Barker- und Golay-codierte Sendesignale
an einer Betonstufenplatte mit einem Größtkorn von 16 mm getestet.

Es zeigt sich das große Potenzial dieses Verfahrens, insbesondere bei Verwendung von Golay-Sequenzen als Anregung für die
Ultraschallprüfköpfe. Es ergibt sich ein deutlich verbessertes Signal-Stör-Verhältnis im Vergleich zu den herkömmlichen
bipolaren Rechteckimpulsen.
An alternative to the geometric addition method for calculating the
rise time of fast oscilloscopes and pulse generators
Authors: Baaske Kai , Hale Paul D. , Kleine-Ostmann Thomas , Bieler Mark , Schrader Thorsten
Published: January 2017

In this paper, we propose a new method for calculating
the rise time of pulse generators and oscilloscopes using a correction
factor. This new method is advantageous over the well
known geometric rule, also known as the
root-sum-of-squares
(RSS) rule, because its corresponding uncertainty
contribution can be estimated, whereas the uncertainty
assigned to the RSS method due to systematic error is typically unknown in
any given measurement scenario. In our
method, the correction factor is estimated from a large
set of representative classical response functions.
Furthermore, the systematic error caused by the time
base distortion of sampling oscilloscopes is corrected in order to reduce
the uncertainty of the calibration process.
Differenzielles kapazitives
Mehrachs-Abstandsmesssystem für Umgebungen mit
elektromagnetischen Störungen
Authors: Schleicher André , Werner Ralf
Published: January 2017

In diesem Beitrag wird
ein kapazitives Abstandsmesssystem mit neuartiger Auswerteelektronik
beschrieben, welches nach dem Prinzip der
Amplitudenmodulation arbeitet und mehrfach differenziell ausgewertet
wird. Durch die Verwendung differenzieller Sensoren wird
der Einfluss der Kapazität vom Messobjekt zum Bezugspotential kompensiert
und im Vergleich zu üblichen kapazitiven Messsystemen eine deutliche
Erhöhung der Störsicherheit gegenüber Potentialänderungen
des Messobjekts erreicht. Die Auswerteelektronik ist
für besonders hohe Trägerfrequenzen konzipiert,
wodurch der Einfluss elektromagnetischer Störungen bis in den
einstelligen MHz-Bereich reduziert
wird. Durch Synchronisation können beliebig viele
Einzelmesssysteme zu einem störsicheren Mehrachsmesssystem kombiniert
werden, welches vor allem den hohen Anforderungen in der
aktiven Magnetlagertechnik gerecht wird.
Formiside and seco-formiside: lignin glycosides from leaves of Clerodendrum formicarum Gürke (Lamiaceae) from Cameroon
Authors: Ahmed Zeeshan , Shaiq Ali Muhammad , Adhikari Achyut , Imran Ali Muhammad , Ngoupayo Joseph , Malik Imran
Published: January 2017

The ethanol soluble part of the leaves of Clerodendrum formicarum, a Lameacious plant of Cameroon, afforded two new lignin glycosides named formiside and seco-formiside. Structures of both the isolated constituents have been elucidated with the aid of 1D and 2D NMR spectroscopic techniques.
Enhancing the Force-Velocity Profile of Athletes Using Weightlifting Derivatives
Authors: Suchomel Timothy J. , Comfort Paul , Lake Jason P.
Published: January 2017

WEIGHTLIFTING MOVEMENTS AND THEIR DERIVATIVES MAY BE IMPLEMENTED IN A SEQUENCED PROGRESSION THROUGHOUT THE TRAINING YEAR TO OPTIMIZE THE DEVELOPMENT OF AN ATHLETE'S STRENGTH, RATE OF FORCE DEVELOPMENT, AND POWER OUTPUT. WEIGHTLIFTING MOVEMENTS AND THEIR DERIVATIVES CAN BE PROGRAMMED EFFECTIVELY BY CONSIDERING THEIR FORCE–VELOCITY CHARACTERISTICS AND PHYSIOLOGICAL UNDERPINNINGS TO MEET THE SPECIFIC TRAINING GOALS OF RESISTANCE TRAINING PHASES IN ACCORDANCE WITH THE TYPICAL APPLICATION OF PERIODIZED TRAINING PROGRAMS.
Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance
Authors: Kerstein Patrick C. , Patel Kevin M. , Gomez Timothy M.
Published: January 2017

Guidance of axons to their proper synaptic target sites requires spatially and temporally precise modulation of biochemical signals within growth cones. Ionic calcium (Ca2+) is an essential signal for axon guidance that mediates opposing effects on growth cone motility. The diverse effects of Ca2+arise from the precise localization of Ca2+signals into microdomains containing specific Ca2+effectors. For example, differences in the mechanical and chemical composition of the underlying substrata elicit local Ca2+signals within growth cone filopodia that regulate axon guidance through activation of the protease calpain. However, how calpain regulates growth cone motility remains unclear. Here, we identify the adhesion proteins talin and focal adhesion kinase (FAK) as proteolytic targets of calpain inXenopus laevisspinal cord neurons bothin vivoandin vitro. Inhibition of calpain increases the localization of endogenous adhesion signaling to growth cone filopodia. Using live cell microscopy and specific calpain-resistant point-mutants of talin (L432G) and FAK (V744G), we find that calpain inhibits paxillin-based adhesion assembly through cleavage of talin and FAK, and adhesion disassembly through cleavage of FAK. Blocking calpain cleavage of talin and FAK inhibits repulsive turning from focal uncaging of Ca2+within filopodia. In addition, blocking calpain cleavage of talin and FAKin vivopromotes Rohon–Beard peripheral axon extension into the skin. These data demonstrate that filopodial Ca2+signals regulate axon outgrowth and guidance through calpain regulation of adhesion dynamics through specific cleavage of talin and FAK.

SIGNIFICANCE STATEMENTThe proper formation of neuronal networks requires accurate guidance of axons and dendrites during development by motile structures known as growth cones. Understanding the intracellular signaling mechanisms that govern growth cone motility will clarify how the nervous system develops and regenerates, and may identify areas of therapeutic intervention in disease or injury. One important signal that controls growth cones is that of local Ca2+transients, which control the rate and direction of axon outgrowth. We demonstrate here that Ca2+-dependent inhibition axon outgrowth and guidance is mediated by calpain proteolysis of the adhesion proteins talin and focal adhesion kinase. Our findings provide mechanistic insight into Ca2+/calpain regulation of growth cone motility and axon guidance during neuronal development.
Posterior α EEG Dynamics Dissociate Current from Future Goals in Working Memory-Guided Visual Search
Authors: de Vries Ingmar E.J. , van Driel Joram , Olivers Christian N.L.
Published: January 2017

Current models of visual search assume that search is guided by an active visual working memory representation of what we are currently looking for. This attentional template for currently relevant stimuli can be dissociated from accessory memory representations that are only needed prospectively, for a future task, and that should be prevented from guiding current attention. However, it remains unclear what electrophysiological mechanisms dissociate currently relevant (serving upcoming selection) from prospectively relevant memories (serving future selection). We measured EEG of 20 human subjects while they performed two consecutive visual search tasks. Before the search tasks, a cue instructed observers which item to look for first (current template) and which second (prospective template). During the delay leading up to the first search display, we found clear suppression of α band (8–14 Hz) activity in regions contralateral to remembered items, comprising both local power and interregional phase synchronization within a posterior parietal network. Importantly, these lateralization effects were stronger when the memory item was currently relevant (i.e., for the first search) compared with when it was prospectively relevant (i.e., for the second search), consistent with current templates being prioritized over future templates. In contrast, event-related potential analysis revealed that the contralateral delay activity was similar for all conditions, suggesting no difference in storage. Together, these findings support the idea that posterior α oscillations represent a state of increased processing or excitability in task-relevant cortical regions, and reflect enhanced cortical prioritization of memory representations that serve as a current selection filter.

SIGNIFICANCE STATEMENTOur days are filled with looking for relevant objects while ignoring irrelevant visual information. Such visual search activity is thought to be driven by current goals activated in working memory. However, working memory not only serves current goals, but also future goals, with differential impact upon visual selection. Little is known about how the brain differentiates between current and future goals. Here we show, for the first time, that modulations of brain oscillations in the EEG α frequency band in posterior cortex can dissociate current from future search goals in working memory. Moreover, the dynamics of these oscillations uncover how we flexibly switch focus between memory representations. Together, we reveal how the brain assigns priority for selection.
Reflections on Law in Light of Everyday Life at L’Arche
Authors: McMorrow Thomas
Published: January 2017

Even though the notion of “disability” has received ongoing critical scrutiny and re-imagination within the field of disability studies, the concept of law has often been taken for granted. Although people with intellectual disabilities figure as subjects of legal discourse, seldom are they presented as participants in it. I argue that this owes to assumptions about law that fail to recognize the diversity of ways human beings exercise agency and experience normativity. I believe that research on the relationship between “law, religion, and disability” stands to benefit from imagining law as an interactional, symbolically plural human endeavour. I build on the theoretical framework of critical legal pluralism to highlight how law arises through interaction – informally and implicitly, as well as officially and explicitly. Drawing on fieldwork I carried out in L’Arche Montréal – a faith-based community serving people with intellectual disabilities – I illustrate the creative role that people with intellectual disabilities play in the construction of legal normativity. As important as it is to ask how law affects people with intellectual disabilities, is to ask about how their actions also shape law. When it comes to asking what law means for some of the most vulnerable members of society, it is not just a question of seeing how it may function either to prevent or to remedy harm. It is also a matter of seeing the ways in which law may facilitate (while being forged by) the cultivation of relationships and the liberation of human potential.
Review of Foucault, Power and Education by Ball
Authors: Castrodale Mark
Published: January 2017

In Foucault, Power and Education, Ball engages in the practice of self to re-examine his own understandings and uses of Foucault. In discussing Foucauldian theory, analytic concepts, and related methods of inquiry, the author demonstrates their usefulness in launching critiques of educational processes, institutions, and policies. He considers how Foucault has shaped his thinking about the possibilities and limits of knowing. This book is a valuable resource for students, course instructors, and researchers in the fields of Disability Studies in Education (DSE), education policy, and Critical Disability Studies (CDS), among others. Ball asserts the need for critical, self-reflexive scholarship and suggests avenues of thought for undertaking this endeavour.
La configuración de la juridicidad y antijuridicidad del daño ambiental y sus diferentes formas de legitimidades
Authors: Munévar Quintero Claudia Alexandra
Published: January 2017

El presente artículo tiene como marco de análisis la configuración del daño ambiental desde sus diferentes formas de legitimidades. El objetivo es develar el contexto constitucional y doctrinal del daño en relación con el ambiente mismo, según su carácter jurídico y anti-jurídico y la relación con víctimas determinadas o indeterminadas, titular de derechos ambientales. En este sentido, mediante la técnica de análisis documental se esbozan los postulados normativos del “ser” y “deber ser” de la norma. Para ello, se parte de la comprensión que el daño, más que una construcción jurídica, tiene una definición social, la cual, a su vez, determina los criterios de juridicidad. Se concluye que este criterio de juridicidad no atiende solamente juicios de razonabilidad, fuerza y poder de un Estado a través de sus normas, sino que son establecidas según los consensos y las re-significaciones sociales. Ampararse en la coacción del derecho y su fuerza arbitraria conlleva a la deslegitimación de las actuaciones legales de un Estado y acentúa la brecha entre la realidad normativa y las realidades sociales.
Apoyo de la gestión universitaria en la protección de las personas menores de edad en el corolario del XXV aniversario de la ratificación de la Convención de los Derechos de los Niños, Niñas y Adolescentes
Authors: González Sandoval German Eduardo
Published: January 2017

El objetivo principal de este ensayo es exponer la manera en que las acciones realizadas en la educación superior deben favorecer la garantía y protección de los derechos de los niños, niñas y adolescentes, ello dentro del entorno de la celebración del XXV Aniversario de la firma y ratificación de la Convención sobre los Derechos de las personas menores de edad, asimismo se plantea un marco teórico analítico e interpretativo de la manera en que tanto a nivel nacional como institucional se enmarcan las responsabilidades sociales con relación con esta temática. Además, se hace un repaso por las acciones desarrolladas desde la División de Educación para el Trabajo a manera de una rendición de cuentas responsable sobre el quehacer en lo correspondiente; se aportan, también, una serie de reflexiones finales acompañadas de una propuesta de ruta a seguir que permita un abordaje pertinente, responsable y comprometido con las necesidades de la población precitada.
Surrogate Pregnancy After Prenatal Diagnosis of Spina Bifida
Authors: Mazur Lynnette J. , Kisthardt Mary Kay , Kim Helen H. , Rosas Laura M. , Lantos John D.
Published: January 2017

Some pregnancies today involve infertile individuals or couples who contract with a fertile woman to carry a pregnancy for them. The woman who carries the pregnancy is referred to as a “gestational carrier.” The use of such arrangements is increasing. Most of the time, these arrangements play out as planned; sometimes, however, problems arise. This article discusses a case in which a fetal diagnosis of spina bifida led the infertile couple to request that the gestational carrier terminate the pregnancy, and the gestational carrier did not wish to do so. Experts in the medical and legal issues surrounding surrogacy discuss the considerations that should go into resolving such a conflict.
Parafrasear: Por quê? Para quê?
Authors: Flôres Onici Claro
Published: January 2017

O presente artigo enfoca a paráfrase enquanto um processo linguístico-cognitivo, fundamentando-se em estudos neurocientíficos (DEHAENE, 2012; IZQUIERDO, 2011; van DIJK, 2010 etc.). Seu objetivo é, através de uma retrospectiva dos estudos já realizados a respeito do tema, como os de Fuchs (1982, 1985) e de outros autores, situar a presente abordagem, destacando a importância da repetição e da paráfrase para a construção do conhecimento. Por fim, sugere que a paráfrase seja reconhecida e valorizada tanto para testar a compreensão leitora quanto para estimular a produção escrita, entre acadêmicos e estudantes dos demais níveis de ensino.
De um lado a outro do eu ao infinito que habita em nós: Uma experiência mística judaica em Clarice Lispector
Authors: Ketzer Estevan De Negreiros
Published: January 2017

O presente ensaio apresenta uma discussão sobre a Kabbalah a partir de uma análise da obra A Paixão Segundo G.H., de Clarice Lispector. O pensamento de Gershom Scholem e suas interpretações a partir de Isaac Luria são chaves de leitura que buscam discutir a experiência secreta humana, proporcionando a sensação do mistério consagrado tanto às letras quanto ao misticismo. Essa interpretação está presente no pensamento judaico, desde a antiguidade até a sensação de vazio interno causado pelo afastamento do ser humano com o Criador. Mostraremos como o texto de Clarice Lispector se aproxima dessa experiência mística de descoberta e entrega.
Literatura & misticismo judaico (Kabbalah)
Authors: Kiefer Charles
Published: January 2017

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