bluuebunny/crossref_metadata_2025 huggingface dataset:
Fecal Calprotectin At The Time Of Diagnosis May Indicate The Presence Of Complications In Inflammatory Bowel Disease
Authors: ERKUT Murat , ÖZKAYA Esra , FİDAN Sami , COŞAR Arif Mansur
Published: February 2024

Aim: We aimed to investigate the relationship between the presence of complications at the time of diagnosis or during follow-up and fecal calprotectin in patients with inflammatory bowel disease.
Materials and Methods: Fecal calprotectin level was studied by the chromatographic lateral flow immunoassay method.
Results: A total of 76 patients, 26 (34%) with Crohn's disease and 50 (66%) with ulcerative colitis, were included in the study. At the time of diagnosis and during follow-up, complications were observed in 17 (22%) and 20 (26%) patients, respectively. At the time of diagnosis, fecal calprotectin level was low (<50 mg/kg) in 26 (34%) patients, borderline (50-100 mg/kg) in 16 (21%) patients, and high (>100 mg/kg) in 34 (45%) patients. Hemoglobin and albumin levels were lower (p=0.013, p=0.012, respectively), and platelet count, eryrocyte sedimentation rate, and C-reactive protein levels were higher (p<0.001, p=0.004, p<0.001, respectively) in patients with high fecal calprotectin level than patients with low fecal calprotectin level. At the time of diagnosis and during follow-up, complications were higher in patients with high fecal calprotectin level than patients with low and borderline fecal calprotectin levels (p=0.001). The risk of developing complications was found to be 26 times higher at the time of diagnosis in patients with fecal calprotectin level >100 µg/g than patients with fecal calprotectin level below this value and 8 times higher during follow-up (p=0.006, p=0.015, respectively).
Conclusion: The use of fecal calprotectin level together with tests showing acute inflammation in inflammatory bowel disease may predict the development of complications.
Ultrasound-guided Barbotage in the Treatment of Calcific Tendinitis
Authors: TUNCER Baran , KARA Onur , ATA Ayşe Merve
Published: February 2024

Not applicable for Letter to the Editor.............................................................................................
Clinical Usefulness of Hematologic Indices in Evaluating Response to Treatment with Anti-Tumor Necrosis Factor-Alfa Agents and Disease Activity in Patients with Ankylosing Spondylitis
Authors: TEZCAN Dilek , KÖREZ Muslu Kazım , HAKBİLEN Selda , KAYGISIZ Mustafa Emin , GÜLCEMAL Semral , YİLMAZ Sema
Published: February 2024

Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease which influences the proportion of immune cells. Tumor necrosis factor alpha (TNF-α) is essential in the pathogenesis of AS, and TNF inhibitors are the most effective treatment for AS patients. In recent years, routine blood parameters were reported as markers of systemic inflammation associated with the diagnosis and prognosis of numerous malignancies and chronic inflammatory diseases. This study aimed to investigate the relationship between haematological parameters and clinical parameters, disease severity and treatment response in AS patients treated with TNF inhibitors.
Methods: A total of 326 participants were recruited from the rheumatology department in this study. Participants were divided into healthy controls (n = 178) and AS (n = 148). Neutrophil, lymphocyte, monocyte and platelet counts, neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), platelet crit (PCT), mean platelet volume (MPV), red cell distribution width (RDW), systemic inflammatory index (SII), systemic inflammatory response index (SIRI), cluster systemic inflammation index (AISI) and RPR levels were analyzed for each participant. They were compared between healthy control, AS patients during the pre-treatment phase and three months after the treatment.
Results: RDW, PLR, NLR, MLR, SIRI, AISI and SII were higher than healthy controls and decreased with treatment except SIRI. The decrease in AISI and SII after treatment was significant in HLA-B27 positive patients. MPV was lower than healthy controls and increased with treatment. SII, SIRI and AISI were significantly higher in the active AS patients than in the inactive patient. Also, they were correlated with erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).
Conclusion: SII, AISI, and SIRI may be valuable markers for demonstrating disease activation and evaluating the effectiveness of anti‐TNF‐α therapy.
Review Article: Welsh in the Contemporary Work–Place
Authors: Screen Ben
Published: February 2024

Y Gymraeg a Gweithlu'r Gymru Gyfoes is an edited volume of contributions with the aim of reflecting on various aspects of using Welsh in the workplace, stemming from a conference on the same theme in 2017 funded by the Coleg Cymraeg Cenedlaethol. An important sphere of
life and one which is essential to effective language planning, a critical discussion of the use of Welsh in the workplace is timely. It includes discussions on various aspects of language planning and policy for the workplace, from Welsh medium provision in higher education to adult second
language acquisition. Overall themes structure the review and individual chapters are reviewed within these themes.
The impacts of YouTube tourism content and YouTuber attributes on tourists’ destination images and behavioral intentions: Focusing on potential Korean tourists to Mongolia
Authors:   The Tourism Sciences Society Of Korea, Maral-Od Lkhagvajav , Roh Hanna , Lee Gyehee
Published: February 2024

Nowadays, YouTube serves not only as a video platform but also as a search engine for online content, providing its viewers with diverse forms of communication and information. The recent and rapid growth of information communication technology has also significantly impacted the tourism industry. Notably, YouTube has emerged as a prominent and burgeoning platform for the creation and dissemination of tourism-related content. This study aims to examine the impact of YouTube tourism content and YouTuber attributes on tourists' destination images and behavioral intentions, specifically focusing on Mongolia, a destination that captures the attention of Koreans but remains relatively unknown. To this end, a sample of 250 adults, who watched Mongolian YouTube videos, was collected using a non-probability sampling method. The analysis revealed that YouTube tourism content and YouTuber attributes had positive influences on cognitive and affective destination images. Furthermore, the cognitive and affective destination images showed significant positive effects on recommendation intentions and visit intentions. Resultingly, all hypotheses suggesting the positive effects of YouTube tourism content and YouTuber attributes on tourists' destination images and behavioral intentions were supported. This study provides meaningful academic implications by contributing to the underdeveloped field of Mongolian tourism research and offers practical insights for the creation and delivery of tourism marketing content via YouTube.
Audiodescripción en clase de lenguas extranjeras: la opinión de los docentes
Authors: Sanz-Moreno Raquel
Published: February 2024

Numerosos estudios han demostrado la validez de las diferentes modalidades de traducción audiovisual (TAV), como el doblaje, la subtitulación o la audiodescripción, como recurso pedagógico para la enseñanza de lenguas extranjeras: contribuyen al desarrollo de competencias comunicativas y resultan en actividades más motivadoras para el alumnado. Sin embargo, pocos trabajos abordan las opiniones de los docentes respecto a la introducción de estas nuevas herramientas didácticas en el aula. Este estudio exploratorio de carácter eminentemente cualitativo persigue recabar y describir las creencias y experiencias de profesores de francés e inglés de secundaria respecto al uso de la TAV, y concretamente de la audiodescripción, en sus clases. A través de un cuestionario completado por 49 profesores y 4 entrevistas, indagamos en la consideración de los docentes de esta modalidad de accesibilidad, con el fin de poner en valor su versatilidad en el aula de lenguas extranjeras. Los resultados demuestran un desconocimiento general de este recurso didáctico y de su potencial. Sin embargo, aquellos docentes que la han empleado en sus clases se muestran entusiastas y reconocen su utilidad.
Correction of the thermal power calculation in the lightweight floor heating based on NT VVS127:2001 standard
Authors: Karpiesiuk Jacek
Published: February 2024

There are many possibilities for determining the thermal power (thermal output) of underfloor heating systems. These may be mathematical, experimental, and numerical methods. Some of them are described in standards, manufacturers’ guides (e.g. charts or tables based on experimental research), as well as programs with numerical calculations. This article concerns the issue of correct calculation of the thermal power only in lightweight underfloor heating without any screeds. It considers the correct entry of the formula for calculating heat power given in the Norwegian standard NT VVS127:2001, relating to a lightweight floor system with metal lamellas. According to the author of this article, there is a significant error in one of the formulas of this standard, which leads to an incorrect final result. This view was based on the results of the author’s calculations and the calculations and conclusions of other scientists. The correction of the incorrectly written formula of the NT VVS127:2001 standard confirms the correctness of the thermal power calculations in a lightweight underfloor heating system with metal lamellas without screeds.
Shelf life extension for yogurt production in circumstances of regular power outages - Eritrean Yogurt Study
Authors: SJ Schneeberger , N Madgwick , L Schotter , U Rohrs Ameen , G Kasozi
Published: February 2024

Due to many parts of Africa suffering from interrupted electrical supply, and hence a broken cold chain, a solution for shelf life extension for perishable foods is needed. An industry that is one of the hardest hit and in most need of shelf life extension is the dairy industry - in particular during yogurt production. It is anticipated that resolving the issue of interrupted electrical supply is improbable in the near future. In Eritrea, yogurt production is at ambient temperatures – approximately 28 oC. After production, the yogurt will go into the fridge with a view to being sold the next day. Electricity supply is unpredictable and can be disrupted for 6 – 12 hours a day. The aim of this study was to determine if the shelf life of yogurt produced in Eritrea under these less-than-ideal conditions could be improved by using natural additives. This study showed that the use of Codex Alimentarius-approved ingredients (native starch, mTGase, Natamycin, and Nisin) when added to the yogurt in the presence of a regularly interrupted electrical supply, produced microbiologically and organoleptically stable yogurt for up to 28 days.
Live-cell imaging; Calcium imaging with Fura-2 v1
Authors: Choi Minee-Liane
Published: February 2024

This protocol describes a method to perform calcium imaging with Fura-2 (live-cell imaging)
BAF_Protocol_003 Desalting v1
Authors: not provided nesf
Published: February 2024

The procedure is used to desalt and purify peptides from solution or in-gel digestion. This step results in minimal losses but increases analytical column life on the mass spectrometer. At the end of the procedure salts and small molecules should be washed away from peptides.
Live-cell imaging; reactive oxygen species (Superoxide) v1
Authors: Choi Minee-Liane
Published: February 2024

This protocol contains the instruction for measuring superoxide using dihydroethidium (HEt) which allows the rate of superoxide generation to be measured which is present as the ratio of the oxidized form of the dye over the reduced form. HEt allows the rate of cytosolic superoxide generation to be measured, by the slope of the ratio of oxidized dye to reduced dye.
Aggregation of human recombinant alpha-synuclein v1
Authors: Choi Minee-Liane
Published: February 2024

This protocol describes a method of generating aggregation of human recombinant alpha-synuclein.
18S rDNA amplification of Kudoa musculoliquefaciens in broadbill swordfish v1
Authors: A Bolin Jessica
Published: February 2024

Protocol for extracting and purifying genomic DNA from Kudoa musculoliquefaciens infecting broadbill swordfish Xiphias gladius, harvested off Eastern Australia. Used in Bolin et al. 2021 Parasitol. Res. (link) and Bolin et al. 2023 in review.
qPCR standard for library quantification v1
Authors: Aximu Petri Ayinuer , Meyer Matthias
Published: February 2024

Protocol for the preparation of a standard for DNA library quantification by quantitative real-time PCR (Meyer et al. 2008; Gansauge et al. 2020). References Meyer, M., Briggs, A. W., Maricic, T., Höber, B., Höffner, B., Krause, J., Weihmann, A., Pääbo, S., & Hofreiter, M. (2008). From micrograms to picograms: Quantitative PCR reduces the material demands of high-throughput sequencing. Nucleic Acids Research, 36(1): e5. Gansauge, M.-T., Aximu-Petri, A., Nagel, S. et al.Manual and automated preparation of single-stranded DNA libraries for the sequencing of DNA from ancient biological remains and other sources of highly degraded DNA. Nature Protocols,15, 2279-2300 (2020).
Purification ofOPTN-GST v1
Authors: Adriaenssens Elias
Published: February 2024

This protocol describes purification of OPTN-GST.
Preparation of Tissue for Volume Electron Microscopy using Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) v1
Authors: C Danne Jillian
Published: February 2024

Volume Electron Microscopy (vEM) allows for the three-dimensional imaging of biological matter and to observe cellular structures at the nanometer scale. This protocol details the preparation of tissue specimens for Focused Ion Beam Scanning Electron Microscopy (FIB-SEM). FIB-SEM gives the highest resolution in z direction compared to other vEM techniques. Images are obtained by stepwise slicing of a specimen using the ion beam while imaging successive surfaces by scanning electron microscopy. Good structural preservation and electron contrast are essential, and this protocol details the required preparatory steps for this up to (but not including) the slice and view imaging in the FIB-SEM.
EMCCD Gain and Offset Calibration v1
Authors: S Beckwith Joseph
Published: February 2024

EMCCD Gain and Offset Calibration
atuação da cada da juventude na formação de lideranças jovens cristãs nas décas de 1970 e 1980
Authors: Ribeiro Marcus , Damasceno Alberto , Golobovante Smile , Almeida Karla
Published: February 2024

Levando em consideração a ação educativa da Igreja Católica no âmbito da educação não-formal, este artigo, situado no campo da história da educação, aborda a atuação da Casa da Juventude (CAJU) na formação de lideranças católicas e tem como objetivo analisar esse processo de formação nas décadas de 1970 e 1980. O trabalho é resultado de uma pesquisa histórico-documental tendo fontes como matérias de jornais, um breve resumo da história da instituição e de seu fundador, Cônego Raul Tavares, disponibilizadas no site oficial da comunidade e uma transcrição do depoimento do fundador sobre sua formação e a criação da CAJU; de entrevistas semiestruturadas com ex-membros da comunidade que relataram sobre suas experiências na Casa; e um pesquisa bibliográfica, no qual realizamos o levantamento de obras que tratam da temática pesquisada. Durante o desenvolvimento da pesquisa, foi possível identificar encontros formativos como a realização de eventos culturais, científicos e espirituais em sua caminhada de evangelização. Inferimos que a CAJU foi uma instituição formativa com vistas a ensinar os seus jovens a se tornarem lideranças católicas capazes de formar outros jovens por meio de uma evangelização crítica e libertadora.
Incidence and outcomes of perioperative myocardial infarction associated with coronary artery bypass surgery
Authors:   Faculty of Medicine, University of Iceland, Heiðarsdóttir Sunna Rún , Heitmann Leon Arnar ,   Faculty of Medicine, University of Iceland, Gunnarsdottir Erla Liu Ting ,   Department of Cardiothoraic Surgery, Landpitali University Hospital, Iceland, Gunnarsdóttir Sunna Lu Xi ,   Department of Cardiothoraic Surgery, Landpitali University Hospital, Iceland, Þorsteinsson Egill Gauti ,   Faculty of Medicine, University of Iceland, Johnsen Árni ,   Department of Cardiothoraic Surgery, Landpitali University Hospital, Iceland, Jeppsson Anders ,   Departments of Cardiothoraic Surgery, Landpitali University Hospital and Sahlgrenska University Hospital in Stockholm, Guðbjartsson Tómas ,   Faculty of Medicine, University of Iceland, Department of Cardiothoraic Surgery, Landpitali University Hospital, Iceland
Published: February 2024

INTRODUCTION: Perioperative myocardial infarction (PMI) after CABG can contribute to in-hospital morbidity and mortality, however, its clinical significance on long-term outcome, remains inadequately addressed. We studied both 30-day mortality and long-term effects of PMI in Icelandic CABG-patients. MATERIALS AND METHODS: A retrospective nationwide-study on 1446 consecutive CABG-patients operated at Landspitali in Iceland 2002-2018 without evidence of preoperative myocardial infarction. PMI was defined as a tenfold elevetion in serum-CK-MB associated with new ECG changes or diagnostic imaging consistent with ischemia. Patients with PMI were compared to a reference group with uni- and multivariate analyses. Long-term and MACCE-free survival were estimated with the Kaplan-Meier method and logistic regression used to determine factors associated with PMI. The mean follow-up time was 8.3 years. RESULTS: Out of 1446 patients 78 (5.4%) were diagnosed with PMI (range: 0-15.5%) with a significant annual decline in the incidence of PMI (12.7%, p<0.001). Over the same period preoperative aspirin use increased by 22.3% (p<0.018). PMI patients had a higher rate of short-term complications and a 11.5% 30-day mortality rate compared to 0.4% for non-PMI patients. PMI was found to be a predictor of 30-day mortality (OR 15.44, 95% CI: 6.89-34.67). PMI patients had worse 5-year MACCE-free survival (69.2% vs. 84.7, p=0,01), although overall survival was comparable between the groups. CONCLUSIONS: Although PMI after CABG is associated with significantly higher rates of short-term complications and 30-day mortality, long-term survival was similar to the reference group. Therefore, the mortality risk attributable to PMI appears to diminish after the immediate postoperative period.
‘Desired’ and ‘Undesired’ Venezuelan Migrants. Discrimination and Differentiation within the Diaspora
Authors: Devis-Amaya Esteban
Published: February 2024

Host societies have several parameters to designate what they consider ‘good’ or ‘desirable’ migrants, compared to ‘bad’ or ‘undesirable’ migrants. Both governments and societies promote these parameters using laws and regulations, such as a points system of immigration; or by exalting or criticizing certain attitudes, conditions, and behaviors, such as praising or even expecting fluency in the host country language. This paper focuses on how the Venezuelan migrants position themselves, and others, within this idea of being ‘desired’ and ‘undesired’ migrants, within the context of Bogotá, Colombia. Using theories of ‘aporophobia’ and ‘pigmentocracy’ as analytical approaches, it discusses how migrants categorize themselves and others, and how they differentiate themselves from those they consider ‘bad’ or less desirable. The paper draws from interviews that took place before the Covid-19 pandemic and analyses how ‘othering’ takes place within migrant communities.
Empathic Divergence: Partially Blunting an Affective Empathic Response While Maintaining Cognitive Empathy is an Important Skill for Medical Students to Acquire
Authors: Newton Bruce , Vaskalis Zachary
Published: February 2024

Background: Establishing an empathic bond of trust with patients is a trait that is important to learn during medical school. There are two types of empathy: affective and cognitive. Being able to partially blunt a detrimental affective response while maintaining cognitive empathy is beneficial for both the patient and the physician. AIM: To find those students who have partially blunted their affective empathy while maintaining or enhancing their cognitive empathic skills. Methods: Affective and cognitive empathy was measured using the Balanced Emotional Empathy Scale and the Jefferson Scale of Empathy, respectively. The survey instruments were given during entrance into medical school, at the start of years 3-4, and a final administration just before graduation. Students who fit the aim of the study, had blunted their BEES score by -0.5 to -1.5 s.d. below the male or female population norms, as well as being at or above the 75th percentile for JSE scores as established by the Project in Osteopathic Medical Education and Empathy study. Desired specialty choice and sex was also collected at each timepoint. Five specialties are “people-oriented” and have a large amount of patient contact and continuity of care, and include Family and Internal Medicine, Ob/Gyn, Pediatrics and Psychiatry. Most other specialties are more “procedure- or technical-oriented” and are those with little or no patient contact and/or continuity of care (e.g., Surgery, Emergency Medicine, Anesthesiology). Results: Only a small subset of students (n = 15/345) fell within the above parameters upon entering medical school. It was a different, small cadre (n = 13) that had these traits upon graduation. Ergo, there was no student who fell within the parameters for all four years of their undergraduate medical education. Conclusions: Few students had the ability to partially blunt their affective empathic response while maintaining the ability to give a reassuring cognitive empathic response to patients. This indicates an increased emphasis needs to be placed on teaching empathic skills during the basic science years of the curriculum. However, the onus needs to fall upon the physicians who are empathic role-models during the clinical rotation year.
Expression of the miR-221/222 cluster can safeguards transplanted HSC from loss of lymphoid-myeloid multipotency
Authors: Melchers Fritz , Jani Peter
Published: February 2024

A microRNA cluster, miR‑221/222, is expressed in quiescent and activated HSC of mice. The expressions of fos and jun, hence AP-1, and a collection of other immediate early genes (IEG), are up-regulated in miR-221/222-deficient HSC. Social stress and HSC transplantation induces comparable up-regulation of IEGs. Stress, as well as miR-221/222-deficiency leads to decreases in the numbers of quiescent HSC and increases in the number of activated hematopoietic (MPP2-4) progenitors, as well as numbers of progenitors of emergency granulopoiesis. Serial transplantations of miR-221/222-deficient HSC generated HSC in the recipient bone marrow, prematurely lose their lymphoid repopulation capacities – normally a sign of aged HSC. Consequently, enforced expression of miR-221/222 should preserve and enhance lymphoid potency of HSC. These results suggest that the expression of miR-221/222 genes themselves and target genes of miR-221/222 in HSC should improve HSC performance in bone marrow niches and their lymphoid development in the transplanted host. Since the miR-221 and -222 genes are also expressed in human HSC, it is likely, that these new targets should be applicable to the improvement of human bone marrow transplantation.
Public Health Implications of Social Media on Adolescent Health Behaviors: Upstream Approaches to Prevention Strategies
Authors: Donnelly Joseph , Saldutti Elena
Published: February 2024

This commentary provides a comprehensive overview of the influence of social media on the health and well-being of adolescents, focusing on emotional/mental health, self-esteem, alcohol and drug use, peer pressure, and both negative and positive influences. It highlights concerns about the potential negative impact of social media, including increased levels of anxiety, depression, and loneliness, as well as the impact on self- esteem through seeking validation and unrealistic comparisons. Furthermore, it discusses how social media exposes adolescents to content promoting alcohol and drug use and amplifies peer pressure, leading to potential substance abuse and negative decision-making. Despite these drawbacks, the abstract acknowledges the positive aspects of social media, such as providing social support, educational resources, and mental health awareness. It emphasizes that social media can be leveraged in the high school classroom to promote healthy behaviors. Strategies for responsible social media use, critical thinking skills, digital literacy, cyberbullying prevention, and content creation are suggested as ways to navigate the online world safely and foster positive online interactions. By understanding both the negative and positive impacts of social media, collectively we can guide adolescents in using social media in a way that promotes resilience, well-being, and healthy habits. Employing strategies that harness the positive aspects of social media, educators, parents, and society can play a pivotal role in helping adolescents navigate the digital landscape, promoting healthy behaviors, and fostering resilience in the face of online challenges.
Countertransference Teaching: The Challenge of Going Beyond Literature: A Novel Approach
Authors: Lewis Owen
Published: February 2024

While countertransference in its various definitions has become central to psychoanalytic theory and practice, and countertransference is acknowledged as central to most care-giving practices, the opportunities to know and explore countertransference in most mental health training programs is limited. Applying approaches of Narrative Medicine didactics, this paper proposes and demonstrates how the group study of clinically relevant literature (novels and short stories) under guided discussion can lead to the identification and exploration of countertransference reactions. The scope of this paper is to report on a single class taught for ten years using literature to teach adolescent development with the finding that it became a forum to explore various countertransference arising in psychotherapies with adolescents, an approach that can be broadly applied.
An Alternative Method of Phacoemulsification Surgery in Eyes with Functional Trabeculectomies
Authors: Murdoch Mr Ian , Mathew Ms Rashmi
Published: February 2024

Aims: To report success proportions in functional trabeculectomised eyes undergoing phaco-emulsifcation with a novel curvilinear capsulorhexis method. Methods: An observational series. Seventy two eyes of 72 patients were identified who underwent cataract surgery in eyes with functional prior trabeculectomy surgery using a Leweke cannula (cases). A previously reported group of 53 eyes in 53 patient who had routine cataract surgery (not using this technique) post-trabeculectomy surgery was used to compare outcomes (controls). Main outcome measure: The primary outcome measure was intraocular pressure (IOP) success (IOP ≤21, ≤18, ≤15 mmHg) at 5 years post cataract surgery. Complete success was no new medication or surgical intervention for IOP and partial success was additional medical therapy required to achieve the IOP target. Results: At final follow-up, the overall failure proportion of the combined groups for an IOP ≤21mmHg was 20% (24/125) at final review. Thirty percent who were a partial success prior to cataract surgery, failed in both controls and cases at final follow-up. Of those who were a complete success prior to phaco-emulsification; 33% were partial successes and 30% failed in the control group; 50% were partial successes and 10% failed in the case group, at final follow-up. Logistic regression for an outcome of failure showed the Leweke cannula to be protective OR 0.28 (95% CI 0.09 to 0.85, p=0.03). African/Caribbean ethnicity was a risk factor for failure. Conclusions: Our results suggest that cataract surgery may affect trabeculectomy outcomes, but not as profoundly as is currently perceived. Using the Leweke technique seems to result in earlier medication recommencement, but a strong reduction in the need for further surgical intervention in fully functional trabeculectomies.
Redefining Health through Multidisciplinary Obesity Prevention and Treatment in the United Arab Emirates
Authors: Alkhatry Maryam , Hamadi Hayder , Alwahedi Abdulwahid , Muzaki Zaki , Ahmed Fathi , Almasri Bashar , Housen Fedaa , Bataweel Mohammed , Alabar Eman , eltayeb Hisham
Published: February 2024

Obesity poses a multifaceted challenge in the United Arab Emirates (UAE), demanding a comprehensive review of its epidemiology, causes, prevention strategies, and challenges. This article explores the intricate web of factors contributing to obesity, emphasizing a multidisciplinary approach that engages nutritionists, exercise physiologists, behavioral therapists, and surgeons. The epidemiology reveals a concerning rise in obesity rates, necessitating targeted interventions. Demographic influences, cultural dynamics, dietary patterns, sedentary lifestyles, and genetic factors are dissected to provide a nuanced understanding. Health implications extend beyond body weight, impacting public health systems and imposing an economic burden. Prevention strategies encompass childhood obesity initiatives, community-based interventions, workplace wellness programs, and government policies. Challenges in implementing these strategies include cultural perceptions of body image, access to healthcare services, socioeconomic disparities, and resistance to change. Cultural sensitivity emerges as a key theme, guiding interventions tailored to align with diverse cultural norms. Multidisciplinary care, leveraging technology, community engagement, and educational programs are explored as integral components of a holistic approach. This review emphasizes the need for societal commitment, empowering communities and individuals, policy advocacy, and the pivotal role of healthcare professionals in the fight against obesity. Future perspectives call for sustained commitment, research investment, and the integration of technology to pave the way for a healthier UAE. This review also provides a roadmap for forging a healthier future, acknowledging the complexity of obesity, and offering insights into tailored, culturally sensitive interventions.
THE INTEGRATION OF TECHNOLOGY AND INNOVATION IN THE DEVELOPMENT OF PATIENT-CENTERED MEDICINE IN THE INTENSIVE CARE UNIT: A LITERATURE REVIEW
Authors: Filho Roberto
Published: February 2024

Since the advent of intensive care units (ICUs) in the twentieth century, several advances have been developed in relation to diagnosis, organ support, and treatment modalities. However, the environment for professionals, patients and their families continues to be stressful and uncomfortable. Optimizing the working conditions and processes of ICUs is of great significance for improving efficiency and minimizing human errors. Innovations and technological advances can also bring higher quality and safer medicine, as well as greater personalization and a better experience for critically ill patients. This article reviews the progress in the related fields that could be the trend in the coming years for the formation of intelligent ICUs. It is discussed how thinking about design, structure, equipment, less invasive monitoring, expansion of digital transformation, incorporation of artificial intelligence, in addition to the perspectives of these changes on the multidisciplinary team, can be important in the search for patient-centered care in the future of the ICUs.
The Skin Cancer Paradox
Authors: DiNardo Joseph
Published: February 2024

Although the safety and efficacy of ultraviolet filters (sunscreens) is widely accepted by consumers and medical professionals, the scientific community has yet to validate this conclusion. This is evident based on multiple literature searches obtained from PubMed, Google Scholar, ScienceDirect, ResearchGate, sunscreen manufacturers and dermatologic organization websites. In the absences of definitive data, industry continues to promote the use of these products to prevent cancers, specifically a 40% reduction in squamous cell carcinoma and a 50% reduction in melanoma based on one confounded non-reproduced study with numerous design flaws. This causes consumers to be misinformed leading them to intentionally increase ultraviolet light exposure, increasing their risk of skin cancers. Until the scientific community can clearly demonstrate that these products reduce/eliminate skin cancers, consumers should follow sun avoidance measures.
Low Loss THz Waveguides and Its Potentials towards 6G Communication: A Brief Chronicle Review
Authors:   Faculty of Electric and Electronic Engineering, Universiti Tun Husein Onn Malaysia, Malaysia, Sohoo Arslan Ahmed
Published: February 2024

Advancement in technology has opened the doors for the terahertz (THz) frequency range to be applied in different fields for various applications. The future communication technology, especially 6G, will also intend to utilize the THz frequency band due to its large bandwidth that has the capabilities to achieve a high data rate. Great losses are presented in the early research into terahertz transmission medium. It is critical to design an appropriate waveguide that can integrate the THz waves into the system efficiently with minimum loss and provides the ease of transmission of data and overcomes the free space loss issues. Communication, sensing, and other application parameters are highly affected by transmission losses; therefore, low transmission loss and dispersion loss waveguide designs are required for proper utilization. In this paper, the review on reduction in the transmission loss in different types of waveguides operating at the Terahertz frequency range is studied. The design and the experimental setup for several classes of THz waveguides for minimizing transmission loss are also discussed. The review study shows that these waveguides can be a promising transmission medium for future 6G communication.
Investigations in Security Challenges and Solutions for M2M Communications—A Review
Authors:   Department of Electronics and Communication Engineering, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Amritapuri, Kollam, Kerala, India, Manikandan A.
Published: February 2024

The Internet of Things (IoT) is becoming increasingly popular, and machine-to-machine (M2M) technology is one of its major components. Reducing human interaction and tasks is one of the most important justifications for research in M2M communication. Also, M2M technology decreases network traffic, improving network effectiveness. In contrast, multiple networks are combined into M2M networks, which leads to security-related design concerns. However, a significant barrier to its growth is security. According to statistics, new gadgets may come under attack five minutes after they connect to the Internet. If these issues are resolved, it will be easier for people to trust this worldview. Security issues with possible solutions have gotten little attention despite extensive M2M studies. This article provides a comprehensive security analysis of M2M communication technologies, exploring the risks and solutions to better comprehend M2M communication and its security implications.
Design and Techno-Economic Analysis of a Hydrogen-Based Micro Hydro-Solar Hybrid Energy System for Sustainable Energy Access: A Case Study in Sri Aman, Sarawak
Authors:   Research Centre for Sustainable Technologies, Faculty of Engineering, Computing, and Science, Swinburne University of Technology, Jalan Simpang Tiga, Kuching, Sarawak, Malaysia, Afrouzi Hadi N.
Published: February 2024

Several rural areas in Sarawak do not have access to electricity. In Sarawak, most investigations prioritize conventional sources despite the emergence of technology such as fuel cells. Furthermore, diversified investigations on stand-alone hybrid renewable energy systems in Sarawak are lacking. This study aims to fill this gap by investigating the feasibility of a stand-alone hybrid renewable energy system for rural applications in Sarawak, with a specific focus on the potential benefits of incorporating hydrogen. Different configurations, namely A: Photovoltaic, hydrogen, micro-hydro, B: hydrogen, micro-hydro, C: micro-hydro, D: photovoltaic, and micro-hydro was explored, each with its results, and comparisons were performed between them. By analyzing the system under various load patterns and conducting a sensitivity analysis, the researchers found that scenario A was the most cost-effective and reliable option for a longhouse in Sri Aman, with a net present cost of $148,687, cost of energy of $0.19/kWh, and initial capital of $107,207. Simultaneously, scenario A has the highest annual generating capacity of up to 116521kWh annually. Sensitivity analysis revealed that the electrolyzer could impact the cost of the system. The electrolyzer is the third and second most expensive in scenarios A and B. This research demonstrates the potential of alternative energy sources to improve access to electricity in rural areas. It highlights the importance of continued exploration into emerging technologies to ensure everyone can access safe and reliable electricity.
Interoperability Challenges in Multivendor IEC 61850 Devices for Parallel Power Transformer Differential Protection
Authors:   Department of Electrical, Electronic, and Computer Engineering, Cape Peninsula University of Technology, Cape Town, South Africa, Shangase Ntokozo N.
Published: February 2024

Interoperability of GOOSE messages is essential for the proper operation of protection schemes such as the parallel power transformer (PTRF) differential protection scheme, especially when using multivendor IEC 61850 devices. GOOSE messages allow for fast and reliable communication between intelligent electronic devices (IEDs) and are based on Ethernet communication. To ensure the interoperability of GOOSE messages between multivendor devices, adherence to the IEC 61850 standard specifications is crucial. The standard defines the format and content of GOOSE messages, including the data object model, data types, and communication protocols. Third-party testing and certification programs can also ensure compliance with the standard and help guarantee interoperability between different vendors. Device conformance with these standards does not ensure interoperability when devices from various manufacturers are utilized. Interoperability is necessary between the relevant devices from various vendors to provide system power stability and protection. If multivendor device interoperability is achieved, power utilities will be able to utilize multivendor devices in substations. The study investigates and provides comprehensive methods for achieving IEC 61850 standard-based interoperability problems in parallel with PTRF’s current differential protection schemes between IEDs (SEL-487E and MiCOM-P645) produced by different vendors under fault conditions. In a lab-scale environment with RTDS for real-time simulation in Hardware-in-the-Loop (HIL), the designed technique is simulated and tested.
Seasonal Variation and Key Variables Affecting Surface Water Quality in North Vam Nao Area, Vietnam
Authors:   College of Environment and Natural Resources, Can Tho University, Can Tho city, Vietnam, Giao Nguyen Thanh
Published: February 2024

Surface water is essential to life, but it is seriously influenced by anthropogenic and natural impacts. Extraction of inside information (for examples sources and key variables influencing water quality) from monitoring data of surface water quality is a crucial task. This study was to intensively evaluate surface water quality in North Vam Nao using Principal Component Analysis (PCA) and Cluster Analysis (CA). The water quality parameters from seven locations during the period 2010–2022 including temperature, pH, total suspended solids (TSS), dissolved oxygen (DO), biological oxygen demand (BOD), chemical oxygen demand (COD), nitrate (NO3−-N), ammonium (NH4+-N), orthophosphate (PO43−-P) and coliforms were collected. The results show that surface water quality is seasonally varied, except for pH. The PCA results predicted the main sources of water pollution were possibly hydrological conditions (rainfall, erosion) and human activities (domestic, agricultural and industrial activities). CA classified the water quality into three clusters for both dry and wet seasons. The common pollutants in both seasons were total suspended solids, organic matters, nutrients, and coliform. All the parameters temperature, pH, TSS, DO, BOD, COD, NH4+-N, NO3−-N, PO43−-P and coliform are key surface water parameters needed to be monitored. The results of the current study could be used for designing surface water monitoring at the study area.
Precipitation Study in Flood Zones: San Mateo Atenco, State of Mexico, Mexico Case Study
Authors:   Postgraduate Studies and Research Section, Zacatenco Campus, National Polytechnic Institute, Mexico City, Mexico, García-Martínez M.
Published: February 2024

This work is focused on analyzing the causes of flooding in the sub-basin belonging to the municipality of San Mateo Atenco: Almoloya-Otzolotepec, because the municipal territory is constantly threatened by hydrometeorological phenomena, such as hailstorms, frost and torrential rains. The maximum precipitation was analyzed in neighboring climatological stations and the precipitation at different return periods (2 to 1000) was determined through the Gumbel distribution, and its impact according to the Thiessen polygon method. With the information of the 24-hour intensities, the Intensity Duration Frequency (IDF) curves and the hietogram of the study area were plotted using the alternating block method. The above procedure was applied to the precipitation data from the 9 stations that affect the basin. The approach proposed in this work considers all the precipitation variables for the best approximation of the phenomena that may occur in the basin; it is an innovative model because it considers the weighted averages of precipitation for each area of influence and its surroundings; this information is useful for the implementation of flood protection projects, adequate design of drainage and sewage systems, and a rational use of the resource to guarantee better living conditions for the inhabitants. According to the results obtained, there is a slow hydrological response and the areas with the greatest runoff potential (8383<CN<100) are located towards the central part of the basin where there is a significant concentration of bare soil.
Design and Validity of Local-Wisdom-Based Reading Apps Using Adobe Animate CC 2022
Authors:   Indonesian Language and Literature Education Department, IKIP PGRI Bojonegoro, Pacul, Indonesia, Hasanudin Cahyo , Fitrianingsih Ayu , Fitriyana Nofia , Ulfaida Nabila
Published: February 2024

Reading activity can be carried out by utilizing various media such as textbooks, digital books, and applications. This study aims to investigate how are the design and validity of local-wisdom-based reading application which is developed using Adobe Animate CC 2022 apps. This study is a stage in developmental research. Research samples are 270 students. The data in designing and validating the application is collected using observation, interview, and questionnaire techniques. It is analyzed using content analysis which is validated using Aiken’s V index. Results of this study in designing and validating a reading app are started from the first step of finding problems. There are three main problems in teaching early reading. The second step is to compile and distribute questionnaire. The questionnaire consists of five questions to investigate students’ needs. The third step is to develop the design and prototype of local-wisdom-based early reading apps which implements Adobe Animate CC 2022 Apps. The fourth step is to conduct evaluation. It involves two material experts of early reading and two learning media experts. Validators’ suggestions have been used to improve the developed application. The conclusion of this study is that the materials of early reading application implement Indonesian local wisdoms which have not implemented in other reading applications.
Attitudes of Graduate and Undergraduate Students towards the Electronic Language Portfolio
Authors:   School of Education, Computense Unversity of Madrid, Spain, Ciesielkiewicz Monika , Bonilla Claire F. , Olave-Lopez-de-Ayala Carlos
Published: February 2024

The aim of this paper is to explore students’ perceptions of the electronic version of the European Language Portfolio (eELP). The participants of this study were students of undergraduate and graduate degrees in education at two private universities in Spain. Both groups used the digital platform of the European Language Portfolio developed by Spanish Service for Internationalization of Education (SEPIE). The authors used a quantitative survey based on two questionnaires that were used in previously published and cited research, administered through Google Forms. The results of this study indicate that both undergraduate and graduate students value the eELP positively, however graduate students were consistently less positive about this tool. The researchers identified statistically significant levels of dissimilarity in four of the nine items on the survey. The findings of this study offer valuable insights into which aspects of the ePortfolio are most relevant to graduate students and which ones to undergraduate students. Additionally, students’ comments complement the survey findings and shed light on what components of eELP could be improved. It is hoped that this research will encourage educators to consider these aspects in the implementation of the eELP in higher education.
Embedded System Training Kit for Artificial Intelligence
Authors:   Department of Electronics and Informatics Engineering Education, Yogyakarta State University, Indonesia, Gusti Wahyu Ramadhani
Published: February 2024

Ever-developing science and technology require us always to be ready to adapt. The current challenging era is Society 5.0, which places a strong emphasis on harnessing human potential to overcome diverse challenges, including the development of Artificial Intelligence (AI) technology. Therefore, to improve the quality of human resources, this paper proposes the development of an artificial intelligence training kit based on embedded systems according to industry needs. The development of a training kit utilizing the RnD method was accomplished through the use of the ADDIE (analysis design, development, implementation, and evaluation) model. This model encompasses analysis, design, development, implementation, and evaluation. The technology of the training kit combines fuzzy logic, Artificial Neural Network (ANN), and image processing, consisting of hardware, software, and job sheets. The controller used to process embedded systems is the ESP32 board. Arduino UNO is used to execute the training results of the artificial intelligence system. The training kit performance test results show that all AI programs run optimally, and each component can function according to performance indicators. A group of subject matter and media experts evaluated the feasibility of the project and determined it to be very feasible, with a score of 83.64% and 86.67%. In addition, a feasibility test was conducted with 38 respondents, resulting in a score of 83.35%, and it was categorized as a very feasible tool. The effectiveness of the training kit applied to the experimental class resulted in a post-test mean score of 89.58, while the control class mean score was 76.39, so the AI training kit showed more effectiveness.