bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating Human–Automation Etiquette Strategies to Mitigate User Frustration and Improve Learning in Affect-Aware Tutoring
Authors: Yang Euijung , Dorneich Michael C.
Published: May 2018

Human–automation etiquette applies human–human etiquette conventions to human–computer interaction (HCI). The research described in this paper investigates how to mitigate user frustration and support student learning through changes in the style in which a computer tutor interacts with a learner. Frustration can significantly impact the quality of learning in tutoring. This study examined an approach to mitigate frustration through the use of different etiquette strategies to change the amount of imposition feedback placed on the learner. An experiment was conducted to explore how varying the interaction style of system feedback impacted aspects of the learning process. System feedback was varied through different etiquette strategies. Participants solved mathematics problems under different frustration conditions with feedback given in different etiquette styles. Changing etiquette strategies from one math problem to the next led to changes in motivation, confidence satisfaction, and performance. The most effective etiquette strategies changed depending on if the user was frustrated or not. This work aims to provide mechanisms to support the promotion of individualized learning in the context of high level math instruction by basing affect-aware adaptive tutoring system design on varying etiquette strategies.
Field Evaluation of Synthetic Polymer Rubber Gel through Filler Content and Oil Leakage Mass Measurement
Authors: Park Jin-sang , Kim Dong-bum , Oh Kyu-hwan , Oh Sang-keun
Published: May 2018

Synthetic Polymer Rubber Gels (SPRG) are used in Composite Modified Bituminous Waterproofing (CMBW) systems for waterproofing in concrete structures. A problem with the current design of SPRG is that when the emulsion breaks, the segregated oil layer can percolate through concrete cracks and cause oil leakage. This study proposes a new evaluation method which assesses the practical performance of SPRG products by testing their susceptibility to filler content settlement and oil leakage. Eight SPRG products used in Korea were used to demonstrate this evaluation method. Each product was installed in a concrete substrate specimen with an artificial crack made in the specimen’s bottom substrate. The specimens were observed for 28 days, and mass of leaked oil, total duration of leakage, average rate of sedimentation, and rheological threshold of initial leakage point were examined as part of the evaluation criteria.
Subliminal Priming—State of the Art and Future Perspectives
Authors: Elgendi Mohamed , Kumar Parmod , Barbic Skye , Howard Newton , Abbott Derek , Cichocki Andrzej
Published: May 2018

The influence of subliminal priming (behavior outside of awareness) in humans is an interesting phenomenon and its understanding is crucial as it can impact behavior, choices, and actions. Given this, research about the impact of priming continues to be an area of investigative interest, and this paper provides a technical overview of research design strengths and issues in subliminal priming research. Efficient experiments and protocols, as well as associated electroencephalographic and eye movement data analyses, are discussed in detail. We highlight the strengths and weaknesses of different priming experiments that have measured affective (emotional) and cognitive responses. Finally, very recent approaches and findings are described to summarize and emphasize state-of-the-art methods and potential future directions in research marketing and other commercial applications.
The Transition between Telomerase and ALT Mechanisms in Hodgkin Lymphoma and Its Predictive Value in Clinical Outcomes
Authors: M’kacher Radhia , Cuceu Corina , Al Jawhari Mustafa , Morat Luc , Frenzel Monika , Shim Grace , Lenain Aude , Hempel William M. , Junker Steffen , Girinsky Theodore , Colicchio Bruno , Dieterlen Alain , Heidingsfelder Leonhard , Borie Claire , Oudrhiri Noufissa , Bennaceur-Griscelli Annelise , Moralès Olivier , Renaud Sarah , Van de Wyngaert Zoé , Jeandidier Eric , Delhem Nadira , Carde Patrice
Published: May 2018

Background: We analyzed telomere maintenance mechanisms (TMMs) in lymph node samples from HL patients treated with standard therapy. The TMMs correlated with clinical outcomes of patients. Materials and Methods: Lymph node biopsies obtained from 38 HL patients and 24 patients with lymphadenitis were included in this study. Seven HL cell lines were used as in vitro models. Telomerase activity (TA) was assessed by TRAP assay and verified through hTERT immunofluorescence expression; alternative telomere lengthening (ALT) was also assessed, along with EBV status. Results: Both TA and ALT mechanisms were present in HL lymph nodes. Our findings were reproduced in HL cell lines. The highest levels of TA were expressed in CD30−/CD15− cells. Small cells were identified with ALT and TA. Hodgkin and Reed Sternberg cells contained high levels of PML bodies, but had very low hTERT expression. There was a significant correlation between overall survival (p < 10−3), event-free survival (p < 10−4), and freedom from progression (p < 10−3) and the presence of an ALT profile in lymph nodes of EBV+ patients. Conclusion: The presence of both types of TMMs in HL lymph nodes and in HL cell lines has not previously been reported. TMMs correlate with the treatment outcome of EBV+ HL patients.
Application of Nanofibrillated Cellulose on BOPP/LDPE Film as Oxygen Barrier and Antimicrobial Coating Based on Cold Plasma Treatment
Authors: Lu Peng , Guo Mengya , Xu Zhijun , Wu Min
Published: May 2018

The application of nanofibrillated cellulose (NC) films in packaging industry has been hindered by its lack of heat-sealing ability. Incorporation of NC films with the biaxially oriented polypropylene/low density polyethylene (BOPP/LDPE) laminates can take advantage of each material and endow the films with novel functions for food packaging applications. In this study, a coating that consists of NC and nisin was applied onto a cold plasma treated BOPP/LDPE film to fabricate a novel active packaging with an improved oxygen barrier performance and an added antimicrobial effect. The results showed that cold plasma treatment improved the surface hydrophilicity of BOPP/LDPE films for better attachment of the coatings. NC coatings significantly enhanced oxygen barrier property of the BOPP/LDPE film, with an oxygen transmission rate as low as 24.02 cc/m2·day as compared to that of the non-coated one (67.03 cc/m2·day). The addition of nisin in the coating at a concentration of 5 mg/g caused no significant change in barrier properties but imparted the film excellent antimicrobial properties, with a growth inhibition of L. monocytogenes by 94%. All films exhibit satisfying mechanical properties and transparency, and this new film has the potential to be used as antimicrobial and oxygen barrier packaging.
Corrosion Resistance of Waterborne Epoxy Coatings by Incorporation of Dopamine Treated Mesoporous-TiO2 Particles
Authors: Wang Na , Diao Xinlin , Zhang Jing , Kang Ping
Published: May 2018

In this paper, waterborne epoxy (EP) coatings were modified by the incorporation of synthetic structure (DA/meso-TiO2) to improve the anticorrosion ability of waterborne epoxy coatings for steel structures. Fourier transform infrared spectroscopy (FTIR), nitrogen adsorption–desorption, X-ray diffraction (XRD) and thermo-gravimetric analyses (TGA) were used to characterize textural properties of DA/meso-TiO2. Corrosion performances of mild carbon steel coated samples were tested by salt spray tests and employing electrochemical impedance spectroscopy (EIS). FTIR, XRD, TGA and nitrogen adsorption–desorption attested to dopamine polymerization within the mesopores and on the surface of meso-TiO2. The results of EIS and salt spray test showed that the specimen coated with 1.0 wt % DA/meso-TiO2 exhibited optimum corrosion performance among other coating specimens.
Sex Chromosomes of the Iconic Moth Abraxas grossulariata (Lepidoptera, Geometridae) and Its Congener A. sylvata
Authors: Zrzavá Magda , Hladová Irena , Dalíková Martina , Šíchová Jindra , Õunap Erki , Kubíčková Svatava , Marec František
Published: May 2018

The magpie moth, Abraxas grossulariata, is an iconic species in which female heterogamety was discovered at the beginning of the 20th century. However, the sex chromosomes of this species have not yet been cytologically identified. We describe the sex chromosomes of A. grossulariata and its congener, A. sylvata. Although these species split only around 9.5 million years ago, and both species have the expected WZ/ZZ chromosomal system of sex determination and their sex chromosomes share the major ribosomal DNA (rDNA) representing the nucleolar organizer region (NOR), we found major differences between their karyotypes, including between their sex chromosomes. The species differ in chromosome number, which is 2n = 56 in A. grossularita and 2n = 58 in A. sylvata. In addition, A. grossularita autosomes exhibit massive autosomal blocks of heterochromatin, which is a very rare phenomenon in Lepidoptera, whereas the autosomes of A. sylvata are completely devoid of distinct heterochromatin. Their W chromosomes differ greatly. Although they are largely composed of female-specific DNA sequences, as shown by comparative genomic hybridization, cross-species W-chromosome painting revealed considerable sequence differences between them. The results suggest a relatively rapid molecular divergence of Abraxas W chromosomes by the independent spreading of female-specific repetitive sequences.
Origin of High Density Seabed Pockmark Fields and Their Use in Inferring Bottom Currents
Authors: Picard Kim , Radke Lynda , Williams David , Nicholas William , Siwabessy P. , Howard Floyd , Gafeira Joana , Przeslawski Rachel , Huang Zhi , Nichol Scott
Published: May 2018

Some of the highest density pockmark fields in the world have been observed on the northwest Australian continental shelf (>700/km2) where they occur in muddy, organic-rich sediment around carbonate banks and paleochannels. Here we developed a semi-automated method to map and quantify the form and density of these pockmark fields (~220,000 pockmarks) and characterise their geochemical, sedimentological and biological properties to provide insight into their formative processes. These data indicate that pockmarks formed due to the release of gas derived from the breakdown of near-surface organic material, with gas accumulation aided by the sealing properties of the sediments. Sources of organic matter include adjacent carbonate banks and buried paleochannels. Polychaetes biodiversity appears to be affected negatively by the conditions surrounding dense pockmark fields since higher biodiversity is associated with low density fields. While regional bi-directionality of pockmark scours corresponds to modelled tidal flow, localised scattering around banks suggests turbulence. This multi-scale information therefore suggests that pockmark scours can act as proxy for bottom currents, which could help to inform modelling of benthic biodiversity patterns.
Primary Care Patients’ Preference for Hospitals over Clinics in Korea
Authors: Kim Agnus M. , Cho Seongcheol , Kim Hyun Joo , Jung Hyemin , Jo Min-Woo , Lee Jin Yong , Eun Sang Jun
Published: May 2018

Korea is in a unique condition to observe whether patients, when equal access to the levels of health care facilities is guaranteed by the support of the national health insurance, choose the appropriate levels of health care facilities. This study was performed to investigate the primary care patients’ preference for hospitals over clinics under no restriction for their choice. We used the 2011 National Inpatient Sample database of the Health Insurance Review and Assessment Service in Korea. A primary care patient was defined as a patient who visited as an outpatient in health care facilities with one of the 52 minor conditions defined by the Korean government. We found that approximately 15% of outpatient visits of the patients who were eligible for primary care in Korea happened in hospitals. In terms of cost, the outpatient visits in hospitals accounted for about 29% of total cost of outpatient visits. This arbitrary access to hospitals can lead to an inefficient use of health care resources. In order to ensure that health care facilities are stratified in terms of access as well as size and function, interventions to distribute patients to the appropriate level of care are required.
Attachment and Survival of Escherichia coli O157:H7 on In-Shell Hazelnuts
Authors: Feng Lingyu , Muyyarikkandy Muhammed S. , Brown Stephanie R. B. , Amalaradjou Mary Anne
Published: May 2018

The multistate Escherichia coli (E. coli) O157:H7 outbreak associated with in-shell hazelnuts highlights the pathogen’s ability to involve non-traditional vehicles in foodborne infections. Furthermore, it underscores significant gaps in our knowledge of pathogen survivability and persistence on nuts. Therefore, this study investigated the ability of E. coli O157:H7 to attach and survive on in-shell hazelnuts. In-shell hazelnuts were inoculated with a four-strain mixture of E. coli O157:H7 at 7.6 log colony forming units (CFU)/nut by wet or dry inoculation, stored at ambient conditions (24 ± 1 °C; 40% ± 3% relative humidity (RH) and sampled for twelve months. For the attachment assay, in-shell hazelnuts were inoculated and the adherent population was enumerated at 30 s−1 h following inoculation. Irrespective of the inoculation method, ~5 log CFU of adherent E. coli O157:H7 was recovered from the hazelnuts as early as 30 s after inoculation. Conversely, pathogen survival was significantly reduced under dry inoculation with samples being enrichment negative after five months of storage (p < 0.05). On the other hand, wet inoculation led to a significantly longer persistence of the pathogen with ~3 log CFU being recovered from the in-shell nuts at 12 months of storage (p < 0.05). These results indicate that E. coli O157:H7 can survive in significant numbers on in-shell hazelnuts when stored under ambient conditions.
Climate Change and Human Health: Health Impacts of Warming of 1.5 °C and 2 °C
Authors: McGushin Alice , Tcholakov Yassen , Hajat Shakoor
Published: May 2018

In December 2015, a historic agreement was reached at the Paris Climate Conference for the first-ever global deal to reduce greenhouse gas emissions.[...]
Neighborhood Built and Social Environments and Change in Weight Status over the Summer in Low-Income Elementary School Children
Authors: Miles Rebecca , Wang Yuxia , Johnson Suzanne Bennett
Published: May 2018

Neighborhoods can provide opportunities for children to maintain a healthy weight or encourage unhealthy weight gain. Which neighborhood characteristics matter most remains poorly understood. We investigated links between neighborhood characteristics and weight change over the summer in children from 12 elementary schools with a high proportion of children from low-income families, in a mid-sized city in the US South. Mixed models and objective measures of height and weight were used. Study participants were 2770 children (average age 8.3, range 5.6–12.6 years). Older and female children and those who were already overweight were more likely to gain weight over the summer compared to younger, male, and normal weight children. Overweight children who lived near 2 or more small grocery stores gained less weight than overweight children who lived near 0 (weight change, p = 0.0468; body mass index (BMI) change, p = 0.0209) or 1 store (weight change, p = 0.0136; BMI change, p = 0.0033). Normal weight children living in neighborhoods with more large multifamily buildings gained more weight over the summer, although this association only approached significance. Additional efforts to understand which neighborhood factors have greater significance for overweight compared to normal weight children are warranted.
Mapping Spatiotemporal Patterns and Multi-Perspective Analysis of the Surface Urban Heat Islands across 32 Major Cities in China
Authors: Wang Juan , Meng Bin , Fu Dongjie , Pei Tao , Xu Chengdong
Published: May 2018

As urban thermal environments are being caused by global climatic changes and urbanization is not uniform on diurnal, seasonal, or annual scales, the spatiotemporal patterns of surface urban heat islands (SUHI) similarly vary between cities across regions. This research assessed the spatiotemporal variations in SUHI intensities (SUHII), and then revealed their spatiotemporal patterns and relationships that existed within 32 major cities in China using spatialization technologies, such as the self-organizing map (SOM) method and statistical methods. Results showed that the spatial patterns of the SUHII patterns in China were significantly affected by the climatic types, whereas human heat discharge also disturbed the patterns to a certain extent. Specifically, the daytime SUHIIs in China had much higher seasonal variations in North China than in South China. The nighttime SUHIIs were much weaker and more stable than the daytime SUHIIs, and had far more obvious spatial patterns with much higher values in North China than in South China. As for the temporal regimes, the temporal variation in the SUHIIs in one city was more related to the development of the urbanization. To be specific, not all cities were experiencing increasingly worse urban thermal environments with urbanization as reported by previous studies. This research not only proposes a spatiotemporal framework to study the SUHIIs patterns and their relationships, but also provides an in-depth and comprehensive understanding of SUHIIs in China.
Role of Vitamin D Beyond the Skeletal Function: A Review of the Molecular and Clinical Studies
Authors: Umar Meenakshi , Sastry Konduru S. , Chouchane Aouatef I.
Published: May 2018

The classical function of Vitamin D, which involves mineral balance and skeletal maintenance, has been known for many years. With the discovery of vitamin D receptors in various tissues, several other biological functions of vitamin D are increasingly recognized and its role in many human diseases like cancer, diabetes, hypertension, cardiovascular, and autoimmune and dermatological diseases is being extensively explored. The non-classical function of vitamin D involves regulation of cellular proliferation, differentiation, apoptosis, and innate and adaptive immunity. In this review, we discuss and summarize the latest findings on the non-classical functions of vitamin D at the cellular/molecular level and its role in complex human diseases.
A Sub-50 µm2, Voltage-Scalable, Digital-Standard-Cell-Compatible Thermal Sensor Frontend for On-Chip Thermal Monitoring
Authors: Kim Seongjong , Seok Mingoo
Published: May 2018

This paper presents an on-chip temperature sensor circuit for dynamic thermal management in VLSI systems. The sensor directly senses the threshold voltage that contains temperature information using a single PMOS device. This simple structure enables the sensor to achieve an ultra-compact footprint. The sensor also exhibits high accuracy and voltage-scalability down to 0.4 V, allowing the sensor to be used in dynamic voltage frequency scaling systems without requiring extra power distribution or regulation. The compact footprint and voltage scalability enables our proposed sensor to be implemented in a digital standard-cell format, allowing aggressive sensor placement very close to target hotspots in digital blocks. The proposed sensor frontend prototyped in a 65 nm CMOS technology has a footprint of 30.1 µm2, 3σ-error of ±1.1 °C across 0 to 100 °C after one temperature point calibration, marking a significant improvement over existing sensors designed for dynamic thermal management in VLSI systems.
Microstructure, Wear Behavior and Corrosion Resistance of WC-FeCrAl and WC-WB-Co Coatings
Authors: Brezinová Janette , Landová Mariana , Guzanová Anna , Dulebová Ľudmila , Draganovská Dagmar
Published: May 2018

The paper is focused on investigating the quality of two grades of thermally sprayed coatings deposited by high-velocity oxygen fuel (HVOF) technology. One grade contains WC hard particles in an environmentally progressive Ni- and Co-free FeCrAl matrix, while the second coating contains WC and WB hard particles in a cobalt matrix. The aim of the experimental work was to determine the effect of thermal cyclic loading on the coatings’ resistance to adhesive, abrasive and erosive wear. Abrasive wear was evaluated using abrasive cloth of two grit sizes, and erosive wear was evaluated by a dry-pot wear test in a pin mill at two sample angles. Adhesion wear resistance of the coatings was determined by a sliding wear test under dry friction conditions and in a 1 mol water solution of NaCl. Corrosion resistance of the coatings was evaluated using potentiodynamic polarization tests. Metallographic cross-sections were used for measurement of the microhardness and thickness and for line energy-dispersive X-ray (EDX) analysis. The tests proved the excellent resistance of both coatings against adhesive, abrasive, and erosive wear, as well as the ability of the WC-WB-Co coating to withstand alternating temperatures of up to 600 °C. The “green carbide” coating (WC-FeCrAl) can be recommended as an environmentally friendly replacement for Ni- and Co-containing coatings, but its operating temperature is strictly limited to 500 °C in air.
Subcritical Water-Carbon Dioxide Pretreatment of Oil Palm Mesocarp Fiber for Xylooligosaccharide and Glucose Production
Authors: Ahmad Norlailiza , Zakaria Mohd Rafein , Mohd Yusoff Mohd Zulkhairi , Fujimoto Shinji , Inoue Hiroyuki , Ariffin Hidayah , Hassan Mohd Ali , Shirai Yoshihoto
Published: May 2018

The present work aimed to investigate the pretreatment of oil palm mesocarp fiber (OPMF) in subcritical H2O-CO2 at a temperature range from 150–200 °C and 20–180 min with CO2 pressure from 3–5 MPa. The pretreated solids and liquids from this process were separated by filtration and characterized. Xylooligosaccharides (XOs), sugar monomers, acids, furans and phenols in the pretreated liquids were analyzed by using HPLC. XOs with a degree of polymerization X2–X4 comprising xylobiose, xylotriose, xylotetraose were analyzed by using HPAEC-PAD. Enzymatic hydrolysis was performed on cellulose-rich pretreated solids to observe xylose and glucose production. An optimal condition for XOs production was achieved at 180 °C, 60 min, 3 MPa and the highest XOs obtained was 81.60 mg/g which corresponded to 36.59% of XOs yield from total xylan of OPMF. The highest xylose and glucose yields obtained from pretreated solids were 29.96% and 84.65%, respectively at cellulase loading of 10 FPU/g-substrate.
UPLC-HRMS-Based Plasma Metabolomic Profiling of Novel Biomarkers by Treatment with KDZI in Cerebral Ischemia Reperfusion Rats
Authors: Wang Chunguo , Liu Chenyue , Wang Min , Ma Quantao , Li Yaqi , Wang Ting , Zhao Baosheng
Published: May 2018

Kudiezi injection (KDZI), also known as Diemailing injection, is a traditional Chinese medicine injection of the composite plant Ixeris sonchifolia Hance (also known as Kudiezi), and has been widely used to treat coronary heart disease, angina pectoris, and cerebral infarction, but its pharmacological mechanisms remain unclear. This study is designed to explore the effects of KDZI on middle cerebral artery occlusion and reperfusion (MCAO/R) rats, and to identify metabolic features of cerebral ischemia reperfusion by using a nontargeted metabolic profiling method based on ultra-performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). In this process, 32 potential biomarkers were found in plasma. KDZI significantly upregulated the levels of taurochenodesoxycholic acid, leucine, l-phenylalanine, l-tryptophan, arachidonic acid (ARA), and phosphatidyl ethanolamines (PE), phosphatidyl cholines (PC) and downregulated the levels of l-valine and 5-hydroxyindole-3-acetic acid (5-HIAA) in plasma. The results indicated that the mechanisms of KDZI on MCAO/R were related to the mechanisms of amino acid and lipid metabolism.
Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors
Authors: Altıntop Mehlika Dilek , Sever Belgin , Akalın Çiftçi Gülşen , Özdemir Ahmet
Published: May 2018

In an attempt to develop potent anticancer agents targeting Akt, new thiazole derivatives (1–10) were synthesized and investigated for their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma, and NIH/3T3 (healthy) mouse embryonic fibroblast cell lines. The most potent compounds were also investigated for their effects on apoptosis and Akt pathway. The most promising anticancer agent was found to be 2-[2-((4-(4-cyanophenoxy)phenyl)methylene)hydrazinyl]-4-(4-cyanophenyl)thiazole (6), due to its selective inhibitory effects on A549 and C6 cells with IC50 values of 12.0 ± 1.73 µg/mL and 3.83 ± 0.76 µg/mL, respectively. Furthermore, compound 6 increased early and late apoptotic cell population (32.8%) in C6 cell line more than cisplatin (28.8%) and significantly inhibited the Akt enzyme. The molecular docking study was performed to predict the possible binding modes of compounds A, 6, and 8 inside the active site of Akt (PDB code: 4EJN). Molecular docking simulations were found to be in accordance with in vitro studies and, hence, supported the biological activity. A computational study for the prediction of absorption, distribution, metabolism and excretion (ADME) properties of all compounds was also performed. On the basis of Lipinski’s rule of five, the compounds were expected to be potential orally bioavailable agents.
The Effect of a New Sodium Bicarbonate Loading Regimen on Anaerobic Capacity and Wrestling Performance
Authors: Durkalec-Michalski Krzysztof , Zawieja Emilia Ewa , Podgórski Tomasz , Zawieja Bogna Ewa , Michałowska Patrycja , Łoniewski Igor , Jeszka Jan
Published: May 2018

Gastrointestinal side effects are the main problem with sodium bicarbonate (SB) use in sports. Therefore, our study assessed the effect of a new SB loading regimen on anaerobic capacity and wrestling performance. Fifty-eight wrestlers were randomized to either a progressive-dose regimen of up to 100 mg∙kg−1 of SB or a placebo for 10 days. Before and after treatment, athletes completed an exercise protocol that comprised, in sequence, the first Wingate, dummy throw, and second Wingate tests. Blood samples were taken pre- and post-exercise. No gastrointestinal side effects were reported during the study. After SB treatment, there were no significant improvements in the outcomes of the Wingate and dummy throw tests. The only index that significantly improved with SB, compared to the placebo (p = 0.0142), was the time-to-peak power in the second Wingate test, which decreased from 3.44 ± 1.98 to 2.35 ± 1.17 s. There were also no differences in blood lactate or glucose concentrations. In conclusion, although the new loading regimen eliminated gastrointestinal symptoms, the doses could have been too small to elicit additional improvements in anaerobic power and wrestling performance. However, shortening the time-to-peak power during fatigue may be particularly valuable and is one of the variables contributing to the final success of a combat sports athlete.
Empirical Study of Communication of Audience Cognition of Environmental Awareness
Authors: Wu Jun , Gao Yang , Tsai Sang-Bing , Lin Rungtai
Published: May 2018

Environmental protection is a vital issue nowadays. Many scholars typically focused on the social aspects of it in their research. For the practical implementation of environmental protection, raising environmental awareness is crucial. With the rapid development of digital media, animation is now used to effectively convey this issue of concern. This study employed qualitative and quantitative methods to explore the effects of viewers’ esthetic experiences and preferences for an original environmental protection-themed sand animation in order to understand cognitive differences between viewers regarding film and television. We selected critical social issues and a popular sand animation for this study. Analyzing the cognitive differences and preferences of the viewers, we identified key factors that attract viewers. The findings were as follows: (1) People gain clear cognition of the environmental protection theme from the sand animation. (2) Innovative perspectives gain recognition more easily. (3) Propagation of environmental awareness to audiences is possible through fiction. (4) Age and professional background cause differences in cognition of film by audience. (5) Different elements of film have different effects on creative intensity and cultural depth.
Mapping Disease Transmission Risk of Nipah Virus in South and Southeast Asia
Authors: Deka Mark A. , Morshed Niaz
Published: May 2018

Since 1998, Nipah virus (NiV) (genus: Henipavirus; family: Paramyxoviridae), an often-fatal and highly virulent zoonotic pathogen, has caused sporadic outbreak events. Fruit bats from the genus Pteropus are the wildlife reservoirs and have a broad distribution throughout South and Southeast Asia, and East Africa. Understanding the disease biogeography of NiV is critical to comprehending the potential geographic distribution of this dangerous zoonosis. This study implemented the R packages ENMeval and BIOMOD2 as a means of modeling regional disease transmission risk and additionally measured niche similarity between the reservoir Pteropus and the ecological characteristics of outbreak localities with the Schoener’s D index and I statistic. Results indicate a relatively high degree of niche overlap between models in geographic and environmental space (D statistic, 0.64; and I statistic, 0.89), and a potential geographic distribution encompassing 19% (2,963,178 km2) of South and Southeast Asia. This study should contribute to current and future efforts to understand the critical ecological contributors and geography of NiV. Furthermore, this study can be used as a geospatial guide to identify areas of high disease transmission risk and to inform national public health surveillance programs.
The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies
Authors: Wong Kai Zhi , Chu Justin Jang Hann
Published: May 2018

Chikungunya virus (CHIKV) has re-emerged as one of the many medically important arboviruses that have spread rampantly across the world in the past decade. Infected patients come down with acute fever and rashes, and a portion of them suffer from both acute and chronic arthralgia. Currently, there are no targeted therapeutics against this debilitating virus. One approach to develop potential therapeutics is by understanding the viral-host interactions. However, to date, there has been limited research undertaken in this area. In this review, we attempt to briefly describe and update the functions of the different CHIKV proteins and their respective interacting host partners. In addition, we also survey the literature for other reported host factors and pathways involved during CHIKV infection. There is a pressing need for an in-depth understanding of the interaction between the host environment and CHIKV in order to generate potential therapeutics.
Equitable and Reasonable Utilization: Reconstructing the Nile Basin Water Allocation Dialogue
Authors: Onencan Abby Muricho , Van de Walle Bartel
Published: May 2018

Equitable and reasonable utilization is a core principle in the distribution of water resources. However, its practical application in the Nile Basin has been a significant challenge, leading to a water allocation deadlock. To address the deadlock, we used the van Eeten (1999) four-step process for defining new agendas. To reconstruct the debate, nine possible water allocation methods are developed using the Stone (2002) framework. After that, the arguments are compared and contrasted using interpretative policy analysis and the relevant factors to determine equitable and reasonable utilization in the Nile basin. Unfortunately, none of the nine possible water allocation methods satisfied all of the factors of assessing equitable and reasonable utilization. Therefore, we identified a crosswalk position that combines three water allocation methods. This combination consists of: (1) a group-based distribution; (2) a value-based distribution; and (3) a consensus-based distribution. Since the crosswalk position does not address current and potential uses, we recommend a new agenda to recast the issue. This agenda entails a change in the recipient of the water resources, the allocated item, and the process of decision-making. Finally, we discuss the potential of applying the proposed methodology in Nile sub-basins and other river basins within Sub-Saharan Africa.
An Assessment of the Microbiological Water Quality of Sand Dams in Southeastern Kenya
Authors: Quinn Ruth , Avis Orlando , Decker Manon , Parker Alison , Cairncross Sandy
Published: May 2018

Sand-storage dams have proven to be a successful water harvesting method and potential solution to water and food security issues in semi-arid regions such as south east Kenya. This paper examines the microbiological quality of water both contained in the sand dam via test holes and abstracted from it through covered wells and scoop holes. In total, the values of thermotolerant coliform (TTC) concentration, turbidity, and pH are presented for 47 covered wells, 36 scoop holes, and 29 test holes, as well as the conductivity values in conductivity in 39 covered wells and 11 scoop holes. The water from test holes and covered wells was microbiologically of better quality than the scoop holes with median TTC levels of 0/100 mL and 159/100 mL respectively. However, the median values of turbidity for both scoop holes (20–30 NTU) and covered wells (5–10 NTU) exceed the World Health Organisation (WHO) guideline values. In addition the conductivity of water from 23% of scoop holes and 26% of covered wells is above the recommended WHO limit. This study also found that sanitary surveys are not a useful indicator of water quality in sand dams; however, they can identify areas in which sanitation and improvement of water sources are needed.
Calibration Parameter Selection and Watershed Hydrology Model Evaluation in Time and Frequency Domains
Authors: Kumarasamy Karthik , Belmont Patrick
Published: May 2018

Watershed scale models simulating hydrological and water quality processes have advanced rapidly in sophistication, process representation, flexibility in model structure, and input data. With calibration being an inevitable step prior to any model application, there is need for a simple procedure to assess whether or not a parameter should be adjusted for calibration. We provide a rationale for a hierarchical selection of parameters to adjust during calibration and recommend that modelers progress from parameters that are most uncertain to parameters that are least uncertain, namely starting with pure calibration parameters, followed by derived parameters, and finally measured parameters. We show that different information contained in time and frequency domains can provide useful insight regarding the selection of parameters to adjust in calibration. For example, wavelet coherence analysis shows time periods and scales where a particular parameter is sensitive. The second component of the paper discusses model performance evaluation measures. Given the importance of these models to support decision-making for a wide range of environmental issues, the hydrology community is compelled to improve the metrics used to evaluate model performance. More targeted and comprehensive metrics will facilitate better and more efficient calibration and will help demonstrate that the model is useful for the intended purpose. Here, we introduce a suite of new tools for model evaluation, packaged as an open-source Hydrologic Model Evaluation (HydroME) Toolbox. We apply these tools in the calibration and evaluation of Soil and Water Assessment Tool (SWAT) models of two watersheds, the Le Sueur River Basin (2880 km2) and Root River Basin (4300 km2) in southern Minnesota, USA.
EMPLOYEES’ INTRAPRENEURIAL ENGAGEMENT INITIATIVES AND ITS INFLUENCE ON ORGANISATIONAL SURVIVAL
Authors: Falola Hezekiah O. , Salau Odunayo P. , Olokundun Maxwell A. , Oyafunke-Omoniy Comfort O. , Ibidunni Ayodotun S. , Osibanjo Omotayo A.
Published: May 2018

Employee intrapreneurial engagement is considered to be one of the fundamental initiatives that can help organisations to achieve a sustainable competitive advantage in the midst of economic hardship and stiff competition particularly in a volatile and competitive business environment. The main objective of this study is to examine how employees’ intrapreneurial engagement initiatives would influence organisational survival. Few studies analyse how employee intrapreneurial engagement may foster organisational survival. In order to bridge this gap, we conducted a survey with three main manufacturing companies in Nigeria. A descriptive research method (Structural Equation Model (AMOS 22)) was applied to analyse the two hundred and fifty-nine (259) copies of valid questionnaire completed by the respondents using stratified and simple random sampling techniques. However, the study indicated that fostering employees’ intrapreneurial engagement have positive significant implications on organisational survival. This suggests that employees’ empowerment, involvement, autonomy, relationships and reward system have significant effects on organisational survival. It is therefore recommended that organisations should challenge their employees by providing them with autonomy and the freedom to innovate and carve out spaces for them to take risks and experiment. The insights discovered from this study would help to facilitate stakeholders to develop or foster employee intrapreneurial engagement and strong institutional strategies to ensure organisational survival.
The CARMENES Search for Exoplanets around M Dwarfs: A Low-mass Planet in the Temperate Zone of the Nearby K2-18
Authors: Sarkis Paula , Henning Thomas , Kürster Martin , Trifonov Trifon , Zechmeister Mathias , Tal-Or Lev , Anglada-Escudé Guillem , Hatzes Artie P. , Lafarga Marina , Dreizler Stefan , Ribas Ignasi , Caballero José A. , Reiners Ansgar , Mallonn Matthias , Morales Juan C. , Kaminski Adrian , Aceituno Jesús , Amado Pedro J. , Béjar Victor J. S. , Hagen Hans-Jürgen , Jeffers Sandra , Quirrenbach Andreas , Launhardt Ralf , Marvin Christopher , Montes David
Published: May 2018

K2-18 is a nearby M2.5 dwarf, located at 34 pc and hosting a transiting planet that was first discovered by the K2 mission and later confirmed with Spitzer Space Telescope observations. With a radius of ∼2 R
⊕ and an orbital period of ∼33 days, the planet lies in the temperate zone of its host star and receives stellar irradiation similar to that of Earth. Here we perform radial velocity follow-up observations with the visual channel of CARMENES with the goal of determining the mass and density of the planet. We measure a planetary semi-amplitude of K

b
 ∼ 3.5

 and a mass of M

b
 ∼ 9 M
⊕, yielding a bulk density around

. This indicates a low-mass planet with a composition consistent with a solid core and a volatile-rich envelope. A signal at 9 days was recently reported using radial velocity measurements taken with the HARPS spectrograph. This was interpreted as being due to a second planet. We see a weaker, time- and wavelength-dependent signal in the CARMENES data set and thus favor stellar activity for its origin. K2-18 b joins the growing group of low-mass planets detected in the temperate zone of M dwarfs. The brightness of the host star in the near-infrared makes the system a good target for detailed atmospheric studies with the James Webb Space Telescope.
Spectroscopic Validation of Low-metallicity Stars from RAVE
Authors: Placco Vinicius M. , Beers Timothy C. , Santucci Rafael M. , Chanamé Julio , Sepúlveda María Paz , Coronado Johanna , Points Sean D. , Kaleida Catherine C. , Rossi Silvia , Kordopatis Georges , Lee Young Sun , Matijevič Gal , Frebel Anna , Hansen Terese T. , Holmbeck Erika M. , Rasmussen Kaitlin C. , Roederer Ian U. , Sakari Charli M. , Whitten Devin D.
Published: May 2018

We present results from a medium-resolution (R ∼ 2000) spectroscopic follow-up campaign of 1694 bright (V < 13.5), very metal-poor star candidates from the RAdial Velocity Experiment (RAVE). Initial selection of the low-metallicity targets was based on the stellar parameters published in RAVE Data Releases 4 and 5. Follow up was accomplished with the Gemini-N and Gemini-S, the ESO/NTT, the KPNO/Mayall, and the SOAR telescopes. The wavelength coverage for most of the observed spectra allows for the determination of carbon and α-element abundances, which are crucial for considering the nature and frequency of the carbon-enhanced metal-poor (CEMP) stars in this sample. We find that 88% of the observed stars have

 ≤ −1.0, 61% have

 ≤ −2.0, and 3% have

 ≤ −3.0 (with four stars at

 ≤ −3.5). There are 306 CEMP star candidates in this sample, and we identify 169 CEMP Group I, 131 CEMP Group II, and 6 CEMP Group III stars from the A(C) versus [Fe/H] diagram. Inspection of the

abundance ratios reveals that five of the CEMP Group II stars can be classified as “mono-enriched second-generation” stars. Gaia DR1 matches were found for 734 stars, and we show that transverse velocities can be used as a confirmatory selection criteria for low-metallicity candidates. Selected stars from our validated list are being followed-up with high-resolution spectroscopy to reveal their full chemical-abundance patterns for further studies.
GW170817 Most Likely Made a Black Hole
Authors: Pooley David , Kumar Pawan , Wheeler J. Craig , Grossan Bruce
Published: May 2018

There are two outstanding issues regarding the neutron-star merger event GW170817: the nature of the compact remnant and the interstellar shock. The mass of the remnant of GW170817, ∼2.7

, implies that the remnant could be either a massive rotating neutron star, or a black hole. We report Chandra Director’s Discretionary Time observations made in 2017 December and 2018 January, and we reanalyze earlier observations from 2017 August and 2017 September, in order to address these unresolved issues. We estimate the X-ray flux from a neutron star remnant and compare that to the measured X-ray flux. If we assume that the spin-down luminosity of any putative neutron star is converted to pulsar wind nebula X-ray emission in the 0.5–8 keV band with an efficiency of 10−3, for a dipole magnetic field with 3 × 1011 G < B < 1014 G, a rising X-ray signal would result and would be brighter than that observed by day 107; we therefore conclude that the remnant of GW170817 is most likely a black hole. Independent of any assumptions of X-ray efficiency, however, if the remnant is a rapidly rotating magnetized neutron star, the total energy in the external shock should rise by a factor ∼102 (to ∼1052 erg) after a few years; therefore, Chandra observations over the next year or two that do not show substantial brightening will rule out such a remnant. The same observations can distinguish between two different models for the relativistic outflow, either an angular or radially varying structure.
Options to Apply the IGSN Model to Biodiversity Data
Authors: Hobern Donald , Hahn Andrea , Robertson Tim
Published: May 2018

For more than a decade, the biodiversity informatics community has recognised the importance of stable resolvable identifiers to enable unambiguous references to data objects and the associated concepts and entities, including museum/herbarium specimens and, more broadly, all records serving as evidence of species occurrence in time and space. Early efforts built on the Darwin Core institutionCode, collectionCode and catalogueNumber terms, treated as a triple and expected to uniquely to identify a specimen. Following review of current technologies for globally unique identifiers, TDWG adopted Life Science Identifiers (LSIDs) (Pereira et al. 2009). Unfortunately, the key stakeholders in the LSID consortium soon withdrew support for the technology, leaving TDWG committed to a moribund technology. Subsequently, publishers of biodiversity data have adopted a range of technologies to provide unique identifiers, including (among others) HTTP Universal Resource Identifiers (URIs), Universal Unique Identifiers (UUIDs), Archival Resource Keys (ARKs), and Handles. Each of these technologies has merit but they do not provide consistent guarantees of persistence or resolvability. More importantly, the heterogeneity of these solutions hampers delivery of services that can treat all of these data objects as part of a consistent linked-open-data domain.

The geoscience community has established the System for Earth Sample Registration (SESAR) that enables collections to publish standard metadata records for their samples and for each of these to be associated with an International Geo Sample Number (IGSN http://www.geosamples.org/igsnabout). IGSNs follow a standard format, distribute responsibility for uniqueness between SESAR and the publishing collections, and support resolution via HTTP URI or Handles. Each IGSN resolves to a standard metadata page, roughly equivalent in detail to a Darwin Core specimen record. The standardisation of identifiers has allowed the community to secure support from some journal publishers for promotion and use of IGSNs within articles.

The biodiversity informatics community encompasses a much larger number of publishers and greater pre-existing variation in identifier formats. Nevertheless, it would be possible to deliver a shared global identifier scheme with the same features as IGSNs by building off the aggregation services offered by the Global Biodiversity Information Facility (GBIF). The GBIF data index includes normalised Darwin Core metadata for all data records from registered data sources and could serve as a platform for resolution of HTTP URIs and/or Handles for all specimens and for all occurrence records. The most significant trade-off requiring consideration would be between autonomy for collections and other publishers in how they format identifiers within their own data and the benefits that may arise from greater consistency and predictability in the form of resolvable identifiers.
Cis pallidus Mellié, 1849: redescription, new synonym, geographic distribution, and host fungi records
Authors: Borlini Paula V. , Lopes-Andrade Cristiano , Araujo Lucimar S.
Published: May 2018

CispallidusMellié, 1849 is redescribed based on specimens from Northeast, Southeast, and South Brazil, and from Argentina. A lectotype is designated forCissemipallidusPic, 1916, and the species is synonymized withC.pallidus. The first host fungi records and a distribution map for the species are provided.
Plectranthias ahiahiata, a new species of perchlet from a mesophotic ecosystem at Rapa Nui (Easter Island) (Teleostei, Serranidae, Anthiadinae)
Authors: Shepherd Bart , Phelps Tyler , Pinheiro Hudson T. , Pérez-Matus Alejandro , Rocha Luiz A.
Published: May 2018

A new species of the perchlet genus Plectranthias is herein described from a single specimen found at Rapa Nui (Easter Island) in the South Pacific. Plectranthiasahiahiata sp. n. was collected at a depth of 83 m in a mesophotic coral ecosystem at Rapa Nui. The main difference between Plectranthiasahiahiata and other members of the genus is higher fin-ray counts (X, 18 dorsal; 18 pectoral) and its distinctive coloration. Compared to the three other known eastern South Pacific species, P.ahiahiata has more dorsal-fin rays, more pectoral-fin rays, fewer tubed lateral-line scales, fewer gill rakers, a longer head relative to SL, a very short first dorsal spine relative to SL, and a short third anal spine relative to SL. Plectranthiasahiahiata is distinguished from western Pacific species, by having more dorsal- and pectoral-fin rays. The closest relative based on genetic divergence (with 12.3% uncorrected divergence in the mitochondrial COI gene) is Plectranthiaswinniensis, a widely distributed species, suggesting important links between Rapa Nui and western Pacific islands. This new species adds to the high endemism of the Rapa Nui ichthyofauna, and is further evidence of the importance of mesophotic reefs as unique communities.