bluuebunny/crossref_metadata_2025 huggingface dataset:
Key directions of implementation of regional economic policy in Russia in the new reality
Authors: Yukhachev S. P. , Menshchikova V. I. , Rodionova N. K.
Published: January 2023

The article reveals the conditions of a new reality for the development of the economy of Russia and its regions, in particular, the increasing trends in the penetration of digital technologies into all spheres of human activity, the impact of the COVID–19 coronavirus pandemic on the economic and social sphere. The essence of the digital economy and the conditions for the successful introduction of digital technologies into the economy and social sphere are revealed. The measures of the federal and regional policy of social support of the population during the COVID–19 coronavirus pandemic are investigated. On the example of the Tambov region, the directions of the implementation of regional economic policy in the conditions of a new reality are considered. The conclusion is made about the sufficiency of regional economic policy measures to achieve the strategic development goals of the region.
Review of: Zackariasson, Ulf. Pragmatic Philosophy of Religion: Melioristic Case Studies.
Authors: Frestadius Simo
Published: January 2023

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Review of: Todd, Patrick. The Open Future: Why Future Contingents are All False.
Authors: Hess Elijah
Published: January 2023

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Inflammatory phenotype, clinicopathologic variables, and effects of long-term methylene blue in dogs with hereditary methemoglobinemia caused by cytochrome b5 reductase deficiency
Authors: Jaffey Jared A. , Wycislo Kathryn L.
Published: January 2023

OBJECTIVE

To determine whether dogs with cytochrome b5 reductase (CYB5R) deficiency have a constitutive proinflammatory phenotype, characterize hematologic and serum chemistry results, and describe changes in methemoglobin (MetHb) levels and serum C-reactive protein (CRP) concentrations after long-term per os (PO) methylene blue (MB) therapy.

ANIMALS

21 client-owned dogs (CYB5R deficient, n = 10; healthy controls, 11).

PROCEDURES

In this prospective, case-control study, methemoglobin levels were measured using a blood gas analyzer with co-oximetry. Plasma tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10) concentrations were measured using a canine-specific multiplex bead-based assay. Serum CRP concentrations were measured with a canine-specific commercial ELISA kit. Serum CRP concentration and MetHb levels were measured in 6 dogs with CYB5R deficiency after ≥ 60 days of PO MB therapy.

RESULTS

As expected, MetHb levels were higher in dogs with CYB5R deficiency compared to controls (P < .001). Plasma TNF-α, IL-6, IL-10, and serum CRP concentrations were no different between CYB5R-deficient and control dogs. Dogs with CYB5R deficiency had lower absolute lymphocyte (P = .005) and eosinophil counts (P = .04) and higher alanine transaminase (P = .04) and alkaline phosphatase activity (P = .02) than controls, but these changes were not clinically relevant. Methemoglobin levels decreased after PO MB therapy (P = .03).

CLINICAL RELEVANCE

These results suggest that otherwise healthy dogs with CYB5R deficiency do not have a constitutive proinflammatory phenotype and clinically relevant abnormalities in hematologic and serum chemistry panels are not expected. Dogs with decreased quality of life attributed to methemoglobinemia from CYB5R deficiency might benefit from PO MB therapy.
Chatbots in Museums: Is Visitor Experience Measured?
Authors: Štekerová Kamila
Published: January 2023

Chatbots are rapidly growing application area of conversational artificial intelligence. The aim of the paper is to explore the evaluation of user experience with chatbot applications in museums and galleries. Introduction to principles of chatbots, their creation and testing is provided. Methods of user experience evaluation are explained and the indicators that can be used to assess user experience with chatbots are listed. History and classification of museum chatbots is briefly summarized. A systematic review according to the PRISMA methodology was conducted to map the latest trends in museum chatbots’ development and namely to answer two research questions: (1) What chatbots have been developed for the needs of museums and galleries? and (2) Was the visitor experience with these chatbots evaluated? The research gap in measuring visitor experience with chatbots was identified.
Los elementos de laboralidad en el trabajo vía plataformas digitales a la luz de la jurisprudencia laboral chilena
Authors: Palavecino Rojas Carla
Published: January 2023

El presente trabajo pretende analizar la existencia de los elementos clásicos de laboralidad en el trabajo vía plataformas digitales, a raíz de la incipiente jurisprudencia emanada de los tribunales laborales especializados, limitado al caso chileno. El análisis que se estructura en los apartados del presente artículo trabaja sobre la base de dos premisas básicas. La primera de ellas dice relación con la incursión de las empresas de plataformas digitales en el mercado nacional y la forma en como este fenómeno vino a poner en tela de juicio la eficacia y poderío de la subordinación o dependencia como elemento configurador e inequívoco, con determinado consenso, de la existencia de relación laboral, ya que esta figura no habría sido suficiente para otorgar la debida protección a quienes desempeñan funciones mediante aplicaciones. En segundo término, se reconoce que el derecho del trabajo y su ámbito normativo es una rama en esencia cambiante que va delimitando su campo de acción conforme evoluciona la relación laboral, siendo, por ende, una regulación reactiva a los cambios sociales, económicos y, en este caso particular, a los tecnológicos, que imperan en una sociedad y en un tiempo determinados. Esta forma de operar, particular pero a la vez lógica, que ha desarrollado el derecho del trabajo nos lleva a la urgente necesidad de determinar cómo se resguardan, cautelan y garantizan los derechos de aquellos que desempeñan trabajos vía plataformas. En este contexto, se tratará de determinar el rol que en este posible ejercicio de “flexibilización” del concepto de subordinación o dependencia juegan los tribunales laborales, teniendo como base de análisis el desarrollo jurisprudencial que han observado las acciones interpuestas en los tribunales competentes, que persiguen la declaración de existencia de relación laboral de aquellos que desempeñan funciones para las empresas de plataformas digitales.
Results of the ‘Reading in the Time of War’ Target Survey of Teenage Bloggers
Authors: Riżko Olena
Published: January 2023

The goal of the ‘Reading in the Time of War’ survey of teenagers was the need to find out the opinions of young book bloggers about what reading is for them now, in the conditions of the full-scale invasion of Russia in Ukraine: a way to normalize the world, an escape from a terrible reality, a means of gaining popularity, or something else. The survey was conducted from July 21 to August 10, 2022, by the method of purposive sampling using Google Forms. It covered 45 bloggers who live in Ukraine or were forced to evacuate abroad. The results showed that for those who like to read, books remain a way (often the only possible) of normalizing the world and getting salvation, an escape from the terrible reality under any force majeure circumstances. Genre literature is in constant demand among teenagers: fantasy/sci-fi, detective, and adventure. Realistic prose became more popular. In addition, teenagers use their own blogs to tell the truth about the war in Ukraine and popularize Ukrainian literature/culture around the world.
Przygotowanie młodzieży do powojennej odbudowy demokratycznego społeczeństwa: rola szkolnictwa ­zawodowego – przypadek Ukrainy
Authors: Ivanytska Olha , Sike Lin
Published: January 2023

Edukacja zawodowa rozumiana jest jako zestaw określonych dziedzin, różnych programów edukacyjnych i szkoleniowych, funduszy, organizacji zawodowych i studenckich, studentów i innych zainteresowanych stron. Ważnym zadaniem edukacji zawodowej jest przygotowanie młodych ludzi do aktywności zawodowej, przygotowanie wykwalifikowanych robotników do pracy w różnych branżach oraz zwiększenie poziomu zatrudnienia w społeczeństwie. Rozwój edukacji zawodowej wymaga uwzględnienia szczegółowych interesów młodzieży oraz czynników, które wpływają na rozpowszechnienie edukacji zawodowej na świecie i jej rozwój. W artykule przedstawiono analizę dotyczącą problematyki przygotowania młodzieży do odbudowy społeczeństwa ukraińskiego po zakończeniu wojny na Ukrainie.
Wpływ wojny na Ukrainie na trendy portalu społecznościowego TikTok
Authors: Kamionka Mateusz
Published: January 2023

TikTok obecnie jest jednym z najszybciej rozwijających się portali społecznościowych na świecie. Coraz większą popularność zyskuje u najmłodszych użytkowników. Platforma ta dzięki swojej funkcji dodawania krótkich filmów jest narzędziem do tworzenia relacji wojennych przez najmłodszych, ale też właśnie tam możemy znaleźć liczne ślady świadczące o dezinformacji i wpływie wojny hybrydowej. W artykule zostały przeanalizowane najpopularniejsze posty zawierające znacznik (hasztag) #Ukraina w trzech różnych językach (angielskim, ukraińskim i rosyjskim), aby pokazać jaki kontent kryje się za najpopularniejszymi postami.
Pathways Towards Future-Ready Indian Cities: Summary of Discussions
Authors: Dubey Manish , Revi Aromar , Jha Deepika , Goswami Amlanjyoti , Wankhade Kavita , Bazaz Amir
Published: January 2023

The eighth edition of the UPD was held over 29-30 November 2022 at IIHS’ Bengaluru City Campus. The convening explored Pathways towards Futureready Indian Cities. This was in recognition of the key role Indian cities have in realising the country’s ambitious economic, developmental, and environmental goals, the serious legacy and emergent challenges they face, and, therefore, the need for reflection on the development agendas that they need to prioritise and pursue. The focus of discussions was on five themes that will determine the preparedness of Indian cities to power rapid, equitable, and sustainable growth and development: next generation urban governance; improving municipal finances; synergising land governance and real estate regulation; accelerating urban infrastructure and service delivery; and decarbonisation.
Adaptations of the News Media and Social Media Logics by Indonesian Political Parties’ Leaders and Presidential Candidates after 2004 Indonesian Presidential Election
Authors: Ahmad Nyarwi
Published: January 2023

Adaptations of political actors and organizations in Asian democratic countries to the media and social media logics have been increasingly visible. This article is specified to answer the following questions of  how Indonesian political parties’ leaders and presidential candidates after  2004 Indonesian presidential election adapted to the news and social media logics and what drove such adaptations.  Focusing on such questions, this article adopts theoretical models of mediatisation of politics formulated by Mazzoleni and Schulz, Strömbäck and Stromback and Van Aelts and extracts in-depth interview data derived from six Indonesian political parties’ leaders, two political consultants and six senior journalists associated with Indonesian media using the qualitative content and thematic analyses. The findings are as follows. These political parties’ leaders and presidential candidates favoured adapting to the news and social media logics when they got to deal with political issues and affairs, formulate political policies and secure their personal images in Indonesian political sphere. Such development was driven by the following factors, including establishing democratic political and media systems, increasing the roles of the media as sources of political information, escalating freedoms of Indonesian media and journalists to manage the media logic. Theoretical implications are chronicled and research recommendations are displayed.
Why Does Generation Z Love Using Apple Products as Personal Branding on Their Social Media?
Authors: Godeliva Gavriella , Gelgel Ni Made Ras Amanda
Published: January 2023

Young people, particularly members of Generation Z, are the technological generations. They are always on the cutting edge of technology. Apple is one of the technology brands with generationally positive sentiment. This generation uses Apple products not only for technical reasons but also as a form of personal branding. They frequently upload photos taken with an Apple device to their social media accounts. Consequently, this paper describes how and why they brand themselves by using Apple products in their Instagram account. Personal branding theory related to impression management theory by Littlejohn and Computer-Mediated Communication (CMC) by Tomic describe these phenomena. The study employed qualitative descriptive methods by interviewing a young apple addict. The outcome of their use of apple products as personal branding is netizens’ favorable perception of social media. They believe that using Apple products will enhance their personal brand. Their personal branding will improve their relationships, friendships, existence, education, and careers, as well as their amusement and usefulness. In order to develop their personal brand, they utilized impression management by displaying an Apple product in a photo or video mirror selfie directly within their Instagram content.
Communication about Traditional Culture through Music Videos of Young Singers in Vietnam
Authors: Nguyen Khang Tan , Man Thach Hue
Published: January 2023

The Vietnamese music market has recently welcomed the phenomenon of young artists using traditional Vietnamese cultural materials to create modern entertainment MV products. In this research, we use qualitative research to identify cultural factors appearing in MVs of two singers Bich Phuong and Hoang Thuy Linh. At the same time, the research team evaluates the effectiveness of integrating Vietnamese cultural elements in the music products of the two singers mentioned above by surveying students of University of Social Sciences and Humanities and Vietnam National University-HCM via a questionnaire. The survey results show that Vietnamese traditional culture is still a topic of interest to many young people. However, instead of learning through traditional channels such as schools and books, the public now has more choices and videos have become one of the most popular approaches thanks to the vivid combination of images and sound. Concurrently, the majority of students said that they regularly follow and watch newly released MVs from artists. The MVs carefully invested in terms of images and skillfully combined folk with modern materials will impress the public and inspire young people to get to know more about conventional values. Traditional culture is expressed through MV. Thereby, it can be seen that the integration of Vietnamese cultural elements into the MV is not only entertaining and educating, improving efficiency in preserving, preserving and spreading diverse and rich cultures, but also imbued with Vietnamese identity.
Tourism Communication in The Development of Sustainable Intelligent Tourism Village in East Lombok As A Supporting Area for Mount Rinjani Global Geopark and Mandalika
Authors: Prihantoro Edy , Monata Rio Setia , Maulana Yusuf , Pertiwi Atit , Widodo Suryarini , Ramadhani Rizky Wulan
Published: January 2023

The development of Indonesian tourism after the Covid-19 pandemic began to rise again. Various efforts have been made by the government and tourism actors to be able to revive  the tourism sector. The purpose of this study is  to analyze tourism communication in the development of a Sustainable Smart Tourism Village in East Lombok as a supporting area for  Mount Rinjani Global Geopark and the Mandalika Special Economic Zone. This study uses a qualitative descriptive method by conducting interviews and direct observations of Loyok Village. The data collected were analyzed using data analysis techniques from Miles Huberman. The results of the study indicate that the development of a sustainable smart tourism village in East Lombok requires collaboration from various parties such as the government, tourism actors, communities, and researchers all at once. The Gunadarma University Matching Fund team is here to help implement five information and communication technologies (ICT) in tourist villages such as making smart homestays, making virtual reality videos, and QR Codes, making new designs for bamboo crafts, and tourist village websites. The application of this technology is also part of communication and is expected to support the development of Loyok Tourism Village in East Lombok Regency. The implementation of ICT in East Lombok Regency is also expected to serve as a pilot project in the development of smart homestays in Indonesia.
Implication Of Malaysia’s Movement Control Order Towards Online News Reading Preference Among Public University Students
Authors: Rahman Saiful Nujaimi Abdul , Rosli Amir Ali , Hashim Norliana , Zainudin Sharifah Sofiah Syed
Published: January 2023

Online news publication had undergone revolutionary changes since the fall of Berlin Wall, 09 November 1989. When Malaysian Government regulated the Movement Control Order (MCO) beginning 18 March 2020 till 03 January 2022 to curb the spread of COVID-19 pandemic, the impact of online news reading became much more significant. This phenomena has brought massive implications to media audience, predominantly among university students – of which, utilizing most of the online news material for their academic references. The online news became major reading materials for the university students in deriving latest information, especially on COVID-19 pandemic. Thus, this study was conducted to identify its implications, news preferences, and satisfaction levels. This purposive random quantitative study had been conducted by disseminating questionnaires via online, due to the restriction of movements. A total of 400 respondents were involved in this study, and interesting findings had been discovered. The study was purposively focused on random public university students within The Klang Valley, due to the fact that students from these universities had been the nation’s catalyst of change ever since. Conclusively, this paper provides significant insights for media practitioners and consumers in developing pertinent strategies for better maneuvering such challenges in our digital future.
Digital Media and Public Access to Educational and Political Information in Pangandaran in the Digital Age
Authors: Maryani Eni , Priyadharma Subekti Wirabhuana , Gemiharto Ilham
Published: January 2023

This study discusses the use of digital media and the public’s access to information in the fields of education and politics in Pangandaran Regency, West Java. In regards to assumptions of the Social Constructionism Theory (SCOT), people’s understandings about the presence of technology in their life    depend on how they interpret and treat the technology. As to the assumptions related to the public sphere, the potential for digital media to serve as a public sphere could also be questioned. This research uses a case study conducted by applying several data collection techniques, namely; in-depth interviews, observation and documentation studies. This study found that the high use of digital media in Pangandaran is not only the result of easy access but also people's perspectives of technology. Digital media can be an alternative to find educational information.  However, there is still a lack of information which is needed very much by the public about educational scholarships and studies at universities.  Meanwhile, political information is limited due to a lack of effort to disseminate government programs that are directly related to or will directly benefit the public. Based on these findings, it can be concluded that digital media has the potential to become a public sphere with a very limited function, namely a sphere where public interests can be discussed and citizens’ awareness of and participation in education and politics can be increased. In addition, the use of digital media can only be increased if there is awareness among individuals or institutions to utilize digital media so that the quality of digital literacy and political will possessed by all parties including the public, government and members of the Pangandaran Regency Regional House of Representatives will improve accordingly.
بحث مستل من " الأمن في الاديان اليهودية والنصرانية والاسلام "
Authors: Saleh Khaled Obaid , HAMMOOD ZEYAD KHALF
Published: January 2023

الإسلام دين الرحمة والعدل ، دين المحبة والأمان ، دين التسامح والتآلف بين الناس أجمعين ، ولا يكون قتال المسلمين وعدوان بعضهم على بعض  سبيلاً للنفع أو الخير في مجتمع مسلم ، مها اختلفت النيات بينهم ، فالمجتمع الآمن الذي يشعر فيه الناس  بحرمة الأنفس والأعراض والأموال فيما بينهم ، ويؤدون فيه شعائرهم الدينية ، ذلك هو المجتمع المسلم المسالم القابل للنمو والارتقاء ، والذي تتحقق فيه الخيرية للأمة
كســـر البناء اللغوي دراسة في أسلوب المطابقة عند المتنبي
Authors: Mohamedamin Youns Othman , Ridha Shaho Othman , Saeed Mohsin Sulaiman
Published: January 2023

تتناول هذه الدراسة كسر البناء اللغوي على عدَّهِ ظاهرة تعتمد الخروج على النمط المثالي للأداء، وهي دراسة تستمد مظاهرها مِن شعر أبي الطيب المتنبي (303هـ - 354هـ) الذي انحرف كثيراً في أساليبه عن النمط المعهود؛ وبحثاً عن تركيب  غير عاديٍّ؛ لغاياتٍ فنيةٍ و جماليةٍ، كسرًا يسبب للمتلقي هزة غير متوقعة، فالمتنبي لدى استعماله الفني للغة؛ و يميل ميلاً شديدًا نحو كسر رتابة النظام اللغوي المعتاد على عدة مستويات. وهذا الانحراف في الأسلوب هو السبب الأول الذي جعل النقاد يعنون بشعره على تعاقب العصور؛ إعجابًا بالطريقة التي عالج بها بعضاً مِن النصوص؛ لأن ما يهم الناقد في النص الشعري لا يتوقف على ما يقوله النص، وإنما الطريقة التي يقال بها النص أيضا.
نمذجة الإشعاع الشمسي في محطة بغداد المناخية وأثره على انتاج الطاقة الكهربائية
Authors: Al-Jubouri Ahmed Taha Shehab , Al-Taay Nuha Turky Hamad
Published: January 2023

اهتم البحث بدراسة الجغرافية المناخية التطبيقية التي تهدف في موضوعها لفهم نماذج الاشعاع الشمس وتحليلها  في محطة بغداد المناخية واثره على انتاج الطاقة الكهربائية لما لها من مساس كبير بالحياة البشرية وامكانية انتاج طاقة كهربائية بوسائل صديقة للبيئة تقلل من حجم التلوث البيئي وتساهم بتوفير طاقة كهربائية باعتماد السيناريو المتوقع من خلال نماذج السطوع الشمسي الفعلي القصير والمعتدل والطويل بدرجة انحراف معياري للمحطة بلغت (6.8) درجة، واحتساب قيم الاشعاع الشمسي الكلي حسب نماذج السطوع الفعلي لمحطة بغداد المناخية خلال مدة الدراسة (1988-2018) بنموذج منخفض ومعتدل وعالي للإشعاع  الشمسي الكلي بحسب دائر العرض التي تقع عليها المحطة وساعات السطوع الشمسي الفعلي بالاعتماد على قانون احتساب الاشعاع الشمسي الكلي لمنظمة الاغذية والزراعة F.A.O، من ثم تحويل قيم سنوات نماذج الاشعاع الشمسي الكلي الى انتاج طاقة كهربائية باستخدام لوح شمسي سليكوني pvاحادي البلورة بكفاءة 12.5% حسب المواصفات القياسية لإنتاج اللوح من الطاقة الكهربائية.
التوزيع المكاني للخدمات التعليمية في حي الغزالية ببغداد لعام 2018
Authors: Salman AL-Obeidi Muthanna Nadhim Dawood , AL-Zubeidi Alaa Talib Judi
Published: January 2023

يعد التعليم واجبا وحقا على الدولة يجب أن توفره  لكل طفل وشخص يستحقه ويلتزم به كل ولي أمر ينتفع من فرصته فيقترن الحق بالواجب وقد أجمع الخبراء على أن التعليم هو خير مقياس يعبر عن مدى تقدم المجتمع أو تخلفه وهو أحد المطالب الأساسية التي يسعى المجتمع إلى تحقيقها إذ إنه استثمار له مردوده الاقتصادي والاجتماعي فقد أصبح التعليم أحد العوامل الأساسية في نجاح أي تنمية . إن الخدمات التعليمية هي إحدى المواضيع الحديثة التي تمكن من دراسة التعليم كظاهرة جغرافية من خلال تمكن الجغرافي و بأسلوبه الخاص من معالجة موضوع التعليم من جوانب متعددة .  ولدراسة التوزيع المكاني للخدمات التعليمية في أي دولة أو مدينة أو حي يجب أن يشمل كل متغيرات وعناصر العملية التعليمية من مدارس وتلاميذ ومعلمين وعدد الشعب وبالتالي فإن دراسة توزيع الخدمات التعليمية يمكن أن يعكس مجموعة العوامل الاقتصادية والاجتماعية والبيئية الكامنة وراء صورة هذا التوزيع . وانطلاقا من هذا كله تم اختيار موضوع هذا البحث من أجل التعرف على التوزيع المكاني للخدمات التعليمية في حي الغزالية ببغداد لعام 2018 وبيان نوع وعدد المؤسسات التعليمية من رياض أطفال والمدارس الابتدائية والمدارس المتوسطة والإعدادية والثانوية . إنّ تعدد مراحل الخدمات التعليمية تدعوا إلى ضرورة تتبع التوزيع المكاني لها وبحسب الحاجة التي تتطلبها كل محلة من هذه الخدمة.ولتحقيق ذلك تم استخدام الأسلوب الإحصائي والذي تمثل في جدولة بيانات التعليم واستخراج النسبة المئوية له وتوزيع انواع التعليم بخرائط واضحة لتحقيق اهداف البحث .
شغب ودورها في البلاط العباسي 279_321هـ/892_932 م
Authors: Jassim Siham Jamil
Published: January 2023

هي زوجة الخليفة العباسي المعتضد بالله وأم الخليفة العباسي المقتدر بالله ، وكانت إحدى جواري الخليفة المعتضد، والسيدة هو اللقب الرسمي لها وشغب لقب أطلقه عليها الخليفة المعتضد؛ لإثارتها للمشاكل والتصق بها. بويع ابنها المقتدر للخلافة وكان عمره ثلاث عشرة سنة واستمر حكمه طوال ربع قرن، تحكمت خلاله السيدة بمقاليد السلطة وظلت تتحكم فيها ربع قرن من الزمان، وهي مدة خلافة المقتدر وقامت شغب بدور كبير ومؤثر في تدبير أمور الدولة وشؤون الحكم بما في ذلك عزل الوزراء وكبار المسؤولين وتعيينه، واستعانت بالعديد من النساء لتنفيذ مؤامراتها ومعاونتها في شؤون الحكم، منها تعيين القهرمانة ثمل بمنصب قاضي القضاة  لتنظر في شكاوى الناس وقضاياهم، فكانت تجلس كل يوم جمعة ويحضر الفقهاء والقضاة وكبار الموظفين والحجاب لتنفيذ أحكامها وتبرز التواقيع وعليها خطها، وبالنظر لاهتمام شغب بالأدوية والسموم للتخلص من كل من يعترض طموحها فقد انشأت مستشفى في بغداد تحت إشرافها كان طبيبه سنان بن ثابت وكان مبلغ النفقة فيه سبعة آلاف دينار.
التوافق المهني وعلاقته بالتفرد- التشارك لدى المرشدين التربويين
Authors: Hassoun Najah Hatem
Published: January 2023

يهدف البحث الى التعرف على العلاقة بين التوافق المهني والتفرد- التشارك  لدى المرشدين التربويين , وللتحقق من أهداف البحث تبنت الباحث مقياس (الغرابي, 2017) الخاص بقياس التوافق المهني , ومقياس (عسل, 2018) الخاص بقياس التفرد- التشارك. وقد اختارت الباحثة عينة عشوائياً بلغت (200) مرشد ومرشدة من مديريات تربية الكرخ ، ثم قامت الباحثة باستخراج الخصائص القياسية لمقاييس البحث لمعرفة مدى ملائمتها للعينة الحالية، وبعد تحليل الاجابات على أدوات البحث أظهرت نتائج البحث أن عينة البحث تمتلك التوافق المهني بمستوى متوسط , وتمتلك التفرد- التشارك بشكل متوازن , وإن العلاقة الارتباطية كانت بين الأفراد الذين يتصفون بالتفردية هي طردية ولكنها غير دالة , أما بالنسبة للأفراد الذين يتصفون بالتشاركية فكانت العلاقة طردية دالة احصائيا, وفي ضوء نتائج البحث  توصلت الباحثة الى بعض التوصيات والمقترحات.
A Phono- Pragmatic Analysis of Threatening and Warning Phrases in Three Selected Speeches of Trump In 2020
Authors: Alkumet Suha Rasheed H.
Published: January 2023

Former President Donald Trump is one of the most political figures to join the United States presidential election. He was known for his use of warning and threatening phrases. In the broader domain of verbal expression in speech, intonation’s function goes beyond the speaker’s level of phrases or sentences. A speaker forms an utterance taking into consideration that it is performed through an expression’s communicative force. In this analysis, a descriptive qualitative methodology is employed to achieve the objectives of the study. The selected speeches are analyzed following Speech Act Theory (SAT) and Brazil’s model to understand the intended meaning of the words. Other researchers in this field of phonology and pragmatics will benefit from this analysis because it clarifies the role of commissive acts and intonation in political speeches. The findings of this study substantiate the importance of Brazil’s model in analyzing tones pragmatically. SAT was utilized to critically evaluate the effectiveness of verbal communication in conveying the speaker’s intention. Based on the study results, it is evident that commissive acts, particularly threats and warning, are present in the three speeches expressed in an indirect illocutionary front.
The Effect of Arabic Verbal and Nominal Clauses on the Writing of English Composition by the Iraqi EFL Learners at the University Level
Authors: Mahmood Mohammed Nadheer
Published: January 2023

This paper tackles specifically the influence of the linguistic interference phenomena of the first language, Arabic, on the Iraqi EFL learners' writings. English nominal clauses have been considered and any phonological and semantic interferences have been excluded. Randomly, 50 subjects from students of the Department of English, University of Mosul, have been chosen. It has been hypothesized that the phenomenon of interference does exist heavily in students' writings and at all grammatical levels. The study is limited to the analysis of students' writings. The study aims at standing on linguistic interference phenomenon of the first language on the foreign language syntactic structure specially on students' writings. Actually, it tries to identify the differences and/or the similarities of both languages. It tries to specify the students' awareness of the syntactic structures and to lessen the errors committed. The analysis depends on the syntactic order of SVO concerning the written sentences following Quirk et al model (1985). The study will increase the students' knowledge of the syntactic structures of both languages in order to overcome any difficulty raised in the learning /teaching contexts.
Evaluation of Phytochemicals And Antioxidant Activity (IC50) of Bintaro Fruit Ethanol Extract (Cerberaodollam L.)
Authors: Adi Prayitno Sutrisno , Puji Lestari Lilla , Retnaningtyas Utami Dwi , Salsabila Nadhifah
Published: January 2023

The phytochemical compounds in bintaro fruit can be used as herbs to maintain health. The compounds that play a role are flavonoids and phenols. These two compounds can be used as a reference for measuring the level of antioxidant activity in natural materials. There is a correlation between total phenols, total flavonoids, and antioxidants (IC50) found in natural ingredients. The purpose of this study was to determine the total phenol content, flavonoids, and antioxidant activity in the ethanol extract of Bintaro fruit. Bintaro fruit was extracted using ethanol solvent by maceration method which was then evaporated with a rotary evaporator on the obtained macerate. The extract obtained was then analyzed for levels of total flavonoids, total phenols, and antioxidants (IC50). Ethanol extract of bintaro fruit in the study produced total phenol content of 73.04 mg GAE/g extract, flavonoids 41.61 mg QE/g extract and had antioxidant activity (IC50=275.06 ppm). Recommended for in vivo or in vitro assay for certain diseases using these extracts.Further research is needed with the use of other solvent to see optimall in the screening of active compounds.
The Beginnings of Hospice Care in the Czech Republic
Authors: Polák Jan , Opatrná Marie , Svatošová Marie
Published: January 2023

The aim of this paper is to review the situation in communist and post-revolutionary Czechoslovakia in the area of palliative care. It will familiarize readers with the enormous efforts of two big personalities in the history of Czech health care: Marie Opatrná and Marie Svatošová, who tried to change the old and inconvenient Soviet health care system and make the care of terminal and dying people more human. At the end, it will present some challenges which the current Czech hospice care is confronted with.
Wybrane aspekty pracy z rodziną w opinii kuratorów sądowych
Authors: Stasiorowski Sławomir , Lewicka-Zelent Agnieszka
Published: January 2023

W procesie zwiększania efektywności pracy kuratorów rodzinnych niezwykle ważne są ich opinie na temat wykonywanej przez nich pracy. Dlatego celem artykułu jest poznanie ich opinii na temat wybranych aspektów zadań podejmowanych w ramach obowiązków służbowych. Na przełomie roku 2020 i 2021 przeprowadzono wywiady indywidualne z 13 kuratorami rodzinnymi, którzy podzielili się swoimi opiniami na temat pozytywnych i negatywnych aspektów swojej pracy. Odnieśli się również do swojego poczucia bezpieczeństwa, roli jaką pełnią oraz trudności, na jakie napotykają podczas pandemii. Uzyskane od osób badanych informacje stanowią podstawę do przeprowadzenia badań ilościowych oraz zaproponowania zmian legislacyjnych.
The family in the age of pandemics – topicality of the message of the exhortation Amoris Laetitia
Authors: Kłos-Skrzypczak Aleksandra Janina
Published: January 2023

The time of the pandemic is a hard test for the family ties. In the face of the difficulties and threats experienced by the families today, the Church reminds spouses about the value of a marriage, which is God’s intention, the fruit of grace and a vocation that must be fully experienced, with fidelity and selflessness. The aim of the research was to present the topicality of the message of the exhortation Amoris laetitia in the context of contemporary events caused by the SARS-Cov-2 virus and underlining the importance of the Church’s tenderness in accompaniment, discreet and full of love, for today’s families. The analytical-synthetic method was used in the work on the text. As a result of the analysis of the content of the exhortation, not so much its topicality was emphasized, but rather the meticulous care for family life in many aspects. Pope Francis, giving specific examples, talks about the topicality of the vocation of the Christian family and the challenges that families had to face during the pandemic. The following conclusion can be drawn from these considerations: each family member, regardless of age or sex, plays an important role in social relations, and in the prose of life, the azimuth of actions should be marked by the ‘Hymn oft love’ by St. Paul.
Komunikacja afektywna a empatia i wartości rodzinne u młodych dorosłych z rodzin monoparentalnych
Authors: Walęcka-Matyja Katarzyna Kamila , Krawczyk Justyna Paulina
Published: January 2023

Tło: Współczesna rodzina zmienia swoją strukturę w wyniku dynamicznego rozwoju technologii, procesów gospodarczych oraz zmian zachodzących na rynku pracy. Rośnie liczba samotnych rodziców wychowujących dzieci, głównie matek.Cel: Cel badań stanowiło określenie zróżnicowania w zakresie komunikacji afektywnej, empatii oraz wartości rodzinnych w grupach młodych dorosłych z rodzin monoparentalnych oraz pełnych. Zbadano także występowanie zależności między komunikacją afektywną a empatią oraz wartościami rodzinnymi.Metodologia: W badaniu zastosowano metodę ilościową, obejmującą zastosowanie kwestionariuszy samoopisowych (Skala Wrażliwości Empatycznej, Indeks Komunikacji Afektywnej, Skala Familizmu oraz ankieta). W badaniu wzięło udział 266 młodych dorosłych (160 kobiet i 106 mężczyzn) z rodzin o zróżnicowanej strukturze (117 osób z rodzin monoparentalnych i 149 osób z rodzin pełnych).Rezultaty: Uzyskane rezultaty wskazują, że młodzi dorośli z rodzin monoparentalnych nie różnią się nasileniem komunikacji afektywnej, empatii oraz wartości rodzinnych od młodych dorosłych z rodzin pełnych. Kobiety z rodzin monoparentalnych uzyskały wyższe nasilenie wartości „sukces materialny i osiągnięcia” niż kobiety z rodzin pełnych. Analiza zależności między komunikacją afektywną a empatią i wartościami rodzinnymi wykazała występowanie słabych związków. Więcej istotnych statystycznie zależności wystąpiło w grupie młodych dorosłych z rodzin pełnych niż w grupie dorosłych z rodzin monoparentalnych.Wnioski: Pochodzenie z rodziny monoparentalnej nie stanowi czynnika ryzyka w obszarze rozwoju analizowanych wymiarów funkcjonowania psychospołecznego tj. komunikacji afektywnej, empatii i wartości rodzinnych.
Qualidade de vida no trabalho segundo profissionais de enfermagem que atuam na Estratégia Saúde da Família
Authors: Beluci Marli Luiz , Melis Taluane Bernardes , Vilas Bôas Ítala Fernanda Gonçalves , Trettene Armando dos Santos , Salgado Manoel Henrique , Beluci Beatriz
Published: January 2023

Objetivo: Analisar a qualidade de vida no trabalho na percepção de profissionais de enfermagem que atuam na Estratégia Saúde da Família. Métodos: Trata-se de um estudo exploratório e descritivo, realizado de agosto a setembro de 2021, cuja amostra foi constituída por 24 profissionais de enfermagem atuantes na Estratégia Saúde da Família em uma cidade no interior do estado de São Paulo, no Brasil. Para a coleta dos dados utilizou-se uma ficha para caracterização dos participantes e o Quality of Working Life Questionnaire - bref (QWLQ-bref). O estudo foi aprovado por Comitê de Ética em Pesquisa em Seres Humanos. Resultados: A qualidade de vida no trabalho apresentou-se de forma satisfatória nos domínios: Físico/Saúde (70,31), Psicológico (63,89), Pessoal (76,56), Profissional (62,85) e no Escore Geral (68,40) do QWLQ-bref. Conclusão: Ressalta-se a importância de analisar a qualidade de vida no trabalho, pois a saúde e a qualidade de vida do trabalhador podem influenciar a atuação profissional.
Digitale Medien versus Tafel und Kreide — Online- und Hybridlehre in der Theoretischen Physik
Authors: Deters Claudius , Menzel Andreas
Published: January 2023

Die Wissensvermittlung in der Theoretischen Physik ist nicht an Demonstrationsexperimente und Versuchsaufbauten vor Ort gebunden. Dies bietet eine erhöhte Flexibilität beim Wechsel zwischen Präsenz- und Online-Lehre. Dennoch sind auch hier einige zentrale Punkte zu beachten. Zum einen sind oft eine schrittweise Entwicklung der Inhalte inklusive Erläuterungen der Dozierenden und Rückfragemöglichkeiten essentiell, damit Kausalketten sowie längere Rechnungen zufriedenstellend vermittelt werden. Zum anderen müssen viele Rechentechniken und symbolische Schreibweisen erst erlernt und geübt werden. Eigenes Schreiben ist hierfür in der Regel unerlässlich. Beim traditionellen Tafelanschrieb und Mitschreiben in Präsenz werden diese Aspekte automatisch berücksichtigt, so dass sich dieses Vorgehen in weiten Bereichen der Theoretischen Physik weiterhin behauptet. Beim Wechsel in die Online-Lehre bildeten wir dieses Format ab, indem wir auf synchrone Veranstaltungen setzten, in denen "live" vor- und mitgeschrieben wurde. Unser Vorgehen evaluierten wir in einer Online-Umfrage. Es stellte sich heraus, dass Teilaspekte unserer Herangehensweise bei der Rückkehr in die Präsenzlehre weiterhin von den Studierenden bevorzugt werden, insbesondere eine digitale Ausführung des Live-Anschriebs. Dies unterstützt hybride Lehrformen, die gleichzeitig in Präsenz und online stattfinden, was sicherlich einen wesentlichen Aspekt der zukünftigen Entwicklung universitärer Lehre darstellt.
Blended Learning mit Jupyter Notebooks
Authors: Brose Jens
Published: January 2023

Seit 2021 findet jeweils in der vorlesungsfreien Zeit im Frühjahr der fakultative Blockkurs „Python in der Physik“ als Blended Learning Programmierkurs mit Wissensvermittlung im Inverted Classroom basierend auf Jupyter Notebooks mit interaktiven Elementen sowie Arbeit an konkreten physikalischen Aufgaben in Kleingruppen im PC-Pool unter Anleitung statt. Im Beitrag werden die organisatorisch-technische Umsetzung sowie die gewonnenen Erkenntnisse aus dieser Veranstaltungsform präsentiert.
Interleukin-6: it’s role in the organism, genetic polymorphism and significance in certain diseases (literature review)
Authors: Р.П. Тийс, , Л.П. Осипова,
Published: January 2023

Данная работа посвящена изучению роли одного из важнейших цитокинов в организме человека, интерлейкина-6 (ИЛ-6). Рассмотрено строение, функционирование молекулы ИЛ-6, связь его уровня в плазме крови с заболеваниями. Подробно описаны данные о генетическом полиморфизме гена ИЛ-6, IL6 G(-174)С, его распространении в человеческих популяциях и ассоциации с различными заболеваниями. Изучение данного цитокина и его генетического полиморфизма актуально с точки зрения популяционной генетики и персонализированной медицины, а также превентивной медицины, которая направлена на принятие профилактических мер и предотвращение развития серьезных недугов.

This work is devoted to the study of the role of one of the most important cytokines in the human organism, interleukin-6 (IL-6). The structure and functioning of IL-6 molecule, the relationship of its level in blood plasma with diseases are considered. Data on genetic polymorphism of IL-6 gene, IL6 G(-174)C, its distribution in human populations and its association with various diseases are also described in detail. The study of this cytokine and its genetic polymorphism is relevant to population genetics and personalized medicine as well as preventive medicine aimed at taking preventive measures and preventing the development of serious diseases.
Experience of Using Lipano in Children with Fatty Acid Oxidation Disorders
Authors: Н.Л. Печатникова, , Н.А. Краснощекова, , В. С. Какаулина,
Published: January 2023

Нарушения митохондриального бета-окисления жирных кислот - группа редких наследственных нарушений обмена веществ. Недостаточность длинноцепочечной 3-гидроксиацил КоА дегидрогеназы жирных кислот (LCHADD) - одно из наиболее частых в странах Европы наследственных нарушений обмена веществ из группы дефектов митохондриального бета-окисления жирных кислот. Это заболевание характеризуется поражением печени, сердечной и скелетной мышц, частыми метаболическими кризами и высокой смертностью в детском возрасте. В данной статье обсуждаются основные принципы диетотерапии при нарушениях окисления жирных кислот с длинной цепью и опыт применения специализированного продукта лечебного питания «Lipano®» (Kanso, Италия) у детей с подтвержденным наследственным нарушением митохондриального бета-окисления жирных кислот.

Disorders of mitochondrial beta-oxidation of fatty acids - a group of rare hereditary metabolic disorders. Deficiency of long-chain 3-hydroxyacyl CoA dehydrogenase of fatty acids (LCHADD) is one of the most frequent in Europe inherited metabolic disorders from the group of defects of mitochondrial beta-oxidation of fatty acids. This disease is characterized by pathology of the liver, heart and skeletal muscle, frequent metabolic crises, and high mortality in infancy. This article discusses the basic principles of diet therapy for long-chain fatty acid oxidation disorders and the experience of using the specialized therapeutic food product «Lipano» (Kanso, Italy) in children with a confirmed hereditary disorder of mitochondrial beta-oxidation of fatty acids.
Xq13.3-q21.1 microduplication in a female fetus: a case report
Authors: К.А. Свирепова, , М.В. Кузнецова, , Н.А. Каретникова, , Д.Ю. Трофимов,
Published: January 2023

Представлено клиническое наблюдение, иллюстрирующее сложность выбора тактики ведения беременности при выявлении участка дупликации хромосомы Х на этапе пренатальной диагностики. Хромосомная перестройка 46,ХХ,dup(X)(q13.3q21.1) диагностирована при молекулярном кариотипировании околоплодных вод у плода женского пола с особенностями фенотипа: полидактилией левой кисти, полидактилией правой кисти под сомнением, гиперэхогенном кишечнике.

We presented a clinical case report about the complexity of the choice of pregnancy management when identifying the X-chromosome duplication using prenatal diagnostic methods. Thus, a chromosomal rearrangement dup(X)(q13.3q21.1) was diagnosed by molecular karyotyping of amniotic fluid in a female fetus with phenotype features: left hand polydactyly, right hand polydactyly in question, hyperechoic intestine.
Е-cadherin in gastric cancer tumorigenesis
Authors: М.В. Немцова, , И.В. Буре, , Д.В. Залетаев, , Е.Б. Кузнецова, , Е.А. Ветчинкина, , А.Д. Молчанов,
Published: January 2023

В основе инвазии и метастазирования опухолевых клеток лежит эпителиально-мезенхимальный переход (ЭМП). При этом состоянии происходит потеря связи между эпителиальными клетками и появляется подвижный фенотип, характерный для мезенхимальных клеток. Важную роль в процессе ЭМП играет белок Е-кадгерин, который устанавливает и поддерживает межклеточные взаимодействия и позволяет эпителиальным клеткам формировать клеточный пласт. Частичная или полная потеря экспрессии E-кадгерина, происходящая при ЭМП, опосредована механизмами, которые блокируют экспрессию активаторов белка и связанных с ним транскрипционных факторов. Напротив, происходит гиперэкспрессия генов его блокаторов SNAIL1/2, ZEB, TWIST1, GRHL2, OVOL1/2 и PRRX1. E-кадгерин задействован в различных онкогенных сигнальных путях, таких как Wnt/β-catenin, Rho GTPase и EGF/EGFR, благодаря чему он способствует развитию многих опухолей, включая рак желудка (РЖ). Важнейшие компоненты эпигенетического контроля экспрессии генов при канцерогенезе - микроРНК и длинные некодирующие РНК - участвуют в регуляции функции Е-кадгерина. Они действуют непосредственно или опосредованно, через многочисленные факторы, контролирующие транскрипцию гена, и таким образом влияют на пролиферацию и метастазирование опухолевых клеток. Этот обзор посвящен роли E-кадгерина в опухолевой прогрессии, а также участию некодирующих РНК в механизмах его экспрессионного контроля при канцерогенезе желудка.

Epithelial-mesenchymal transition (EMT) is the basis of tumor invasion and metastasis. It is characterized by the loss of communication between epithelial cells, which lead to the appearance of a motile phenotype of mesenchymal cells. The E-cadherin protein plays an important role in the EMT process, establishing and maintaining intercellular interactions and allowing epithelial cells to form a cell layer. The partial or complete loss of E-cadherin expression that occurs during EMT is mediated by mechanisms that block the expression of activators of this protein and related transcription factors. In contrast, the inhibitors of E-cadherin SNAIL1/2, ZEB, TWIST1, GRHL2, OVOL1/2, and PRRX1 are overexpressed. E-cadherin is involved in various oncogenic signaling pathways such as Wnt/β-catenin, Rho GTPase and EGF/EGFR. Therefore it contributes to many tumors, including gastric cancer (GC). MicroRNAs and long noncoding RNAs as important epigenetic regulators of gene expression in carcinogenesis are also involved in the regulation of E-cadherin function. They act directly or indirectly, through multiple factors controlling gene transcription, and thus influence tumor cell proliferation and metastasis. This review is focused on the role of E-cadherin in tumor progression and the involvement of non-coding RNAs in the mechanisms controlling its expression in gastric carcinogenesis.
Lysosomal diseases and common neurodegenerative diseases: a common mechanism of pathogenesis
Authors: Д.В. Кистол, , Е.Ю. Захарова, , П.Г. Цыганкова,
Published: January 2023

Лизосомные болезни накопления (ЛБН) представляют собой группу, включающую около 70 заболеваний, характеризующихся дисфункцией лизосом, большинство из которых наследуются аутосомно-рецессивно. Несмотря на то, что каждая нозология сама по себе является довольно редким заболеванием, общая распространенность ЛБН, по разным оценкам, составляет от 1:5 000 до 1:7 500 живых новорожденных, с более высокой частотой в определенных этнических группах (финны, евреи-ашкенази). Накопление макромолекул внутри органелл эндосомно-аутофагической лизосомальной системы рассматривают в качестве основного механизма патогенеза всех ЛБН. В последние десятилетия особый интерес вызывают общие механизмы патогенеза, лежащие в основе развития ЛБН и распространенных нейродегенеративных заболеваний, таких как болезни Альцгеймера, Паркинсона, боковой амиотрофический склероз. В данном обзоре рассмотрены основные общие молекулярно-генетические механизмы, лежащие в основе патогенеза этих двух групп заболеваний. Понимание общности развития этих сходных групп заболеваний позволит по-новому взглянуть на их природу и перспективы медикаментозной терапии.

Lysosomal storage diseases (LSDs) comprise the group of about 70 disorders characterized by lysosomal dysfunction, most of which have autosomal recessive trait of inheritance. Despite the fact that each nosology itself is a rather rare disease, the overall prevalence of LSD ranges from 1:5,000 to 1:7,500 among newborns, with a higher incidence among the population (Finns, Ashkenazi Jews). The accumulation of macromolecules in the organelles of endosomal-autophagic-lysosomal system is considered to be a common link of the pathogenesis for all LSD. Last decade, there has been a particular interest in the common ground of pathogenesis underlying the development of lysosomal diseases and frequent neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis. This review we provide the main molecular mechanisms underlying these two human disease groups. Understanding the resemblance of the pathogenesis of theses groups can help for look at their etiology from the other side and open new perspectives on the drug therapy.