bluuebunny/crossref_metadata_2025 huggingface dataset:
СПОРТИВНО-ПОЛІТИЧНИЙ ТУРИЗМ ВИДАТНИХ СПОРТСМЕНІВ ПО КРАЇНАХ СВІТУ (НА ПРИКЛАДІ ПОЇЗДОК ФУТБОЛІСТА Д. МАРАДОНИ Й БОКСЕРА М. ТАЙСОНА)1
Authors: Кулик Сергій , Тарадюк Роман
Published: January 2025

Famous people (artists, singers, athletes) often pay private visits to countries around the world at the invitation of their heads of state. The authors of the article propose to use the new term “sports and political tourism” to describe such trips with the aim of public support of state leaders, their political course, participa- tion in political actions and events. On the basis of contacts and meetings of the famous footballer D. Maradona with the head of the State Council of Cuba, the presidents of Venezuela, Nicaragua, Russia, Chechnya, and boxer M. Tyson with the presidents of Chechnya and other well-known Russian politicians, the features of sports and political tourism are analyzed. Based on various research methods (behaviorist, comparative, structural-functional) and tourism classifica- tions, we argue that sports and political tourism is an elite non-permanent indi- vidual international tourism of middle-aged people. It is also amateur short-term tourism with a combined purpose (sports and political). At the same time, sports and political tourism is driven by the political interests of the host country. These are trips by athletes on the occasion of certain sporting events and activities, and/ or public support for heads of state during their election campaigns, on the eve of election day. Heads of state have also engaged athletes to participate in politi- cal actions during international conferences. Thus, sports and political tourism influences the domestic and foreign policies of countries around the world. Based on the behavior and statements of sports and political tourists, the authors of the article also conducted a SWOT analysis of sports and political tourism.
ЕВОЛЮЦІЯ СЮЖЕТНОГО НАРАТИВУ НАТО В КОНТЕКСТІ СТРАТЕГІЧНИХ КОМУНІКАЦІЙ ФІНЛЯНДІЇ Й ШВЕЦІЇ
Authors: Благовірний Максим
Published: January 2025

The article traces the change in the vector of international and security policy of Finland and Sweden in view of their accession to NATO. The author analyses the transformation of the role of these countries in the international community and the impact of their strategic communications on solving global problems and confronting global security challenges both now and in the future. The main focus is on the intergovernmental consensus policy of Finland and Sweden, the relationship between domestic public debates on security and defence, public opinion and strategic thinking in the Nordic countries. It is predicted that the strengthening of the Northern bloc in NATO can enhance the military potential of not only Northern but also the whole of Europe, thus not only reducing the vulnerability of NATO’s frontline countries but also possibly changing the course of the Russian-Ukrainian war.
ЗМІНИ СТРАТЕГІЧНИХ КОМУНІКАЦІЙ УКРАЇНИВ ЧАС РОСІЙСЬКО-УКРАЇНСЬКОЇ ВІЙНИ (2022–2024 РР.)1
Authors: Юськів Богдан , Карпчук Наталія , Пелех Оксана
Published: January 2025

Unpredictability caused by various factors, especially changes in the enemy’s strategy and tactics on a changing battlefield is one of the main specificities of strategic communications. On February 24, 2022, a new stage of the Russian- Ukrainian war began, associated with new challenges not only on the battle- field, but also in the information sphere. There is an aggravation of the confron- tation, which goes beyond the traditional propaganda of the Russian Federation and which is full of aggression not only against Ukraine and Ukrainian society, but also against the Western world. The purpose of this article is to inves- tigate how the strategic communications of Ukraine changed/evolved during 2022–2024 in the conditions of a full-scale war of the RF against Ukraine. The authors claim that Ukraine’s strategic communications have been undergoing three types of changes: adaptation, regulation, and innovation. Adaptation of strategic communications takes place in accordance with constant changes in the political, social and information environment. Ukraine’s strategic commu- nications proved to be flexible and ready to quickly respond to new challenges and situations. Regulation involved analyzing previous mistakes, successes and making necessary adjustments to improve existing competencies and capabili- ties in accordance with the changing realities of war. This included changing approaches to communicating with audiences, reassessing the effectiveness of previous strategies and optimizing them to achieve better results. Innovations have opened up new opportunities for Ukraine’s strategic communications. The use of digital platforms, social media, artificial intelligence, virtual rea- lity, big data analysis and other innovative tools made it possible to implement advanced approaches, improve the effectiveness of communications, attract more attention to key messages and initiatives, and ensure deeper engagement with the audience. All these three types of changes in strategic communications reflect the flexibility, adaptability and progressive nature of Ukrainian strategic communications in the complex conditions of war and information warfare.
Effectiveness of solution-focused brief counseling to increase achievement motivation of bullying victims
Authors: Wiyono Bambang Dibyo , Nuryono Wiryo , Ghozali Muhamad Afifuddin , Adebowale Olusegun Fatai , Kamal Akmal Nasri , Putri Aulia Ramadhani
Published: January 2025

The phenomenon of bullying has been a problem in almost every school, and many factors have been attributed to someone becoming a victim of bullying. The intimidation that occurs to victims of bullying has a negative impact on many facet of their live, one of which is a decrease in academic achievement due to lack of motivation. Achievement motivation is required by every student to accomplish academic tasks and achieve set goals, especially victims of bullying who have low achievement motivation. This study aims to test the effectiveness of the Solution-Focused Brief Counseling approach to increase the achievement motivation of students who are victims of bullying at SMP Negeri 35 Surabaya. This study uses a quantitative approach adopting pre-test post-test control group research design. The research participants comprised 6 students of class VIII of SMP Negeri 35 Surabaya who were selected using simple random sampling technique which were then divided into 2 groups, namely the experimental group and the control group. Data collection was carried out using a scale instrument for bullying victims and achievement motivation which had been tested for validity and reliability. This study consisted of 3 treatment meeting sessions and 2 test sessions, namely pre-test and post-test. Data were analyzed using the Mann-Whitney test. The results showed a significant increase in achievement motivation of bullying victims in the experimental group compared to the control group (0.046 < 0.05). So it can be concluded that individual counseling with the Solution-Focused Brief Counseling approach has proven effective in increasing the achievement motivation of bullying victims. Solution-focused brief counseling can be an option for school counselors to increase the achievement motivation of students who are victims of bullying.
Efektivitas model pembelajaran berdiferensiasi pendidikan anak usia dini untuk mendukung kurikulum merdeka
Authors: Syisva Syisva , Kurniah Nina , Suryadi Didik , Kristiawan Muhammad , Risdianto Eko
Published: January 2025

Tujuan dari penelitian ini untuk menentukan bagaimana guru dapat menggunakan berbagai pendekatan pembelajaran untuk memenuhi kebutuhan dan karakteristik unik setiap anak. Dengan menggunakan observasi, wawancara, dan dokumentasi sebagai teknik pengumpulan data, penelitian ini menggunakan pendekatan kualitatif untuk mengeksplorasi dan memahami masalah yang terjadi. Peneliti berpendapat bahwa model pembelajaran berdiferensiasi efektif digunakan untuk memenuhi kebutuhan unik setiap anak. Model pembelajaran berdiferensiasi yang diterapkan di PAUD dapat meningkatkan keinginan siswa untuk belajar, memenuhi kebutuhan belajar setiap anak, membantu mereka mencapai potensi mereka, mendukung pembelajaran inklusif, mengurangi stres dan tekanan, dan mendorong semua orang untuk belajar bersama, anak-anak usia dini memiliki beragam perkembangan yang meningkatkan keterlibatan dan motivasi siswa, meningkatkan kemandirian dan rasa percaya diri, relevan dengan kurikulum merdeka dalam konteks kurikulum yang fleksibel seperti kurikulum merdeka, mendukung guru dalam mengelola keberagaman kelas, mendukung konsep bermain sambil belajar dan membantu mereka mencapai potensi terbaik mereka.
SIMULATION OF PLACEMENT FOR FOAM INLET INJECTOR POSITION ON FIREFIGHTER JET NOZZLE
Authors: Hadi Sutrisno Himawan , Kusumohadi Catur Setyawan , Yudistira Nopel Syahdan
Published: January 2025

Water is a widely used and effective fire-extinguishing medium, but its effectiveness diminishes at high temperatures. By disrupting the oxygen chain in the fire triangle, Foam media can enhance suppression performance. This study simulates the impact of foam injector placement on the effectiveness of jet nozzles in fire extinguishers. Simulations were conducted with foam injectors positioned at the nozzle's inlet, middle, and outlet. Results indicate that placing the foam injector at the outlet provides optimal spray velocity, pressure, and extinguishing performance. These findings highlight the importance of injector placement in improving fire suppression efficiency for liquid-based extinguishing systems.
MONTE CARLO ANALYSIS OF FETAL DOSE DISTRIBUTION IN PREGNANCY FOR DIFFERENT FETAL AGES, BEAM LOCATION, BEAM ENERGY, AND FIELD SIZES
Authors: Yani Sitti , Ramadhan Muhammad Vitro , Sumaryada Tony , Rhani Muhammad Fahdillah , Husin Abd. Djamil , Yani Sitti
Published: January 2025

Treatment with radiotherapy in pregnant women may occur due to some critical conditions. The dose given during the treatment process is not only received by the patient but can also be absorbed by the fetus which can affect its growth. Moreover, the radiation target is near the fetus such as the lung. This study aims to determine the dose distribution to the fetus with variations in fetal age (trimester 1, 2, and 3), beam energy, field size, and fetal distance to the target location (lung). The entire simulation utilized the Monte Carlo-based software EGSnrc-DOSXYZnrc which produced a 3-dimensional dose distribution on the virtual phantom. The simulated virtual phantom is a box with a size of 40×40×40 cm3 containing several materials, namely water, tissue, and lung. The size of the fetus is varied according to trimesters 1, 2, and 3. The beam is in the form of monoenergetic photons with energies of 3 MeV and 5 MeV emitted from above with a source to surface distance (SSD) of 48 cm. The field size was set at 5×5 cm2 and 8×8 cm2 on the phantom surface. The beam axis was located at a distance of 5 cm and 3 cm from the fetus. The results showed that the four variations performed affected the fetal dose, where the fetal dose increased considerably when the field size was enlarged and the beam axis was closer to the fetal position. The increase in fetal dose is also influenced by the increase in fetal age and beam energy. Meanwhile, the location of the beam below the lung causes an increased dose to the fetus due to the closer position of the beam to the fetus.
DEVELOPMENT OF A LITHIUM-ION BATTERY CHARGING SYSTEM UNDER CONSTANT CURRENT AND VOLTAGE CONDITIONS USING STM-32 BASED ON FUZZY LOGIC CONTROL
Authors: Asy'ari Muhammad Khamim , Panggabean David Keyvin Sabam Halomoan , Musyafa' Ali , Ginting Kevin Bestian
Published: January 2025

Lithium-ion batteries are electrical energy storage devices often found in portable electronic equipment. Overcharging and discharging the battery will reduce its life and cause severe damage. Constant current and voltage control methods and control algorithms, such as fuzzy logic control, need to be added to avoid this. This research aims to develop a lithium-ion battery charging system using a constant current and voltage method based on fuzzy logic control. A constant current-constant voltage (cc-cv) charging system helps control the charging voltage and current by conditioning the initial charging to use a constant current so as not to overcharge. Constant current uses a buck converter circuit, while constant voltage uses a voltage regulator circuit. The charging system is equipped with a voltage sensor and a current sensor. System control uses fuzzy logic control methods with input variables as errors and delta errors while the output is a duty cycle. The overall system design was carried out at the Measurement, Reliability, Risk, and Safety Laboratory, ITS for 4 months. The test results show that charging the battery produces a voltage of 12.6 Volts and a current of 2.5 Amperes. The battery will be fully charged, and the charging system will stop when the flowing current decreases and the current is cut off at 100 mA.
Penerapan Model Pembelajaran Problem Based Learning Berbantuan Canva untuk Meningkatkan Minat Belajar Peserta Didik Pada Mata Pelajaran Pendidikan Pancasila Kelas VII.B SMP Negeri 16 Mataram
Authors: Azwari Riki , Mustari Mohamad , Andriani Widyan
Published: January 2025

Tujuan dari penelitian ini yaitu untuk meningkatkan minat belajar peserta didik kelas VII B SMPN 16 Mataram pada mata pelajaran Pendidikan Pancasila melalui model Problem Based Learning (PBL) berbantuan media canva. Metode penelitian yang diterapkan adalah penelitian Tindakan kelas. Hasil penelitian menunjukkan bahwa minat belajar peserta didik mengalami peningkatan. Minat belajar peserta didik pada pre-test kriteria rendah 17 peserta didik atau 54,8%, sedang 6 peserta didik atau 19,3%, tinggi 8 peserta didik atau 25,8%. Sedangkan pada post-tes kriteria rendah turun menjadi 1 peserta didik atau 3,2%, kriteria sedang menjadi 6 peserta didik atau 9,3% dan kriteria tinggi naik menjadi 24 peserta didik atau 77,4%. Pengunaan Problem based learning sudah terlaksana sesuai dengan sintak pembelajarannya dan dalam prosesnya peserta didik antusias mengikuti setiap langkah pembelajaran, aktif bertanya dan teribat dalam proses diskusi. Pemanfaatan media efektif untuk meningkatkan minat belajar pada pelajaran Pendidikan Pancasila. Tampilan yang menarik perhatian peseta didik melalui media canva dapat meningkatkan minat belajar peseta didik.
Growth Pattern and Morphometric Characteristics of Keting Mystus gulio (Hamilton, 1822) in Downstream of Gembong and Rejoso River, Pasuruan, Indonesia
Authors: Lestariaji Chandika , Herawati Endang Yuli , Arfiati Diana , Djaduk Saddam Langkung , Ristianadewi Priska , Anjasmara Aang Setyawan , Valina Rahmi
Published: January 2025

Keting fish is a type of fish from freshwater which is usually used as a consumption fish or ornamental fish. There is a type of kein, namely from the species Mystus gulio (Hamilton, 1922). Mystus gulio ecosystem is disturbed due to land-use change activities in the river which causes the disturbance of the habitat of Mystus gulio. The purpose of this study is to analyze the long-weight relationship, growth pattern, and condition factors of Mystus gulio in downstream Gembong and  Rejoso River. The method used in this study is to sample Mystus gulio from 3 stations on each river based on land use criteria. The research was carried out for 3 months, namely August, September and October 2023. The results of this study show that Mystus gulio caught in these two rivers all have a negative allometric growth pattern (b<3). The average value of the condition factor in these two rivers is 1 which indicates that the condition of Mystus gulio is good. The average growth of Mystus gulio caught in Gembong is relatively larger than Rejoso. The waters quality results of Gembong and Rejoso are still in optimal condition, except for Total Suspended Solid and Lead (Pb).
Analyzing Land Conversion Rate and Conversion Farmer Household Food Security in Bakalan Village, Pasuruan Regency
Authors: Novianty Puput Cindy , Soemarno  , Efani Anthon
Published: January 2025

The conversion of agricultural land to non-agricultural uses presents significant challenges to food security, environmental sustainability, and economic progress in Bakalan Village. Food security categories for Bakalan Village conversion farmer families are assessed in this study using System Dynamic and Land Conversion Rate Analysis. A causal loop diagram illustrates the complex relationships between land conversion, food availability, affordability, and needs, crucial for understanding food security dynamics. Higher land conversion rates negatively impact food availability, risking local food security. System Dynamic integrates agricultural and non-agricultural income sources to model food affordability, a key food security determinant. Annual iterations capture fluctuations in land use, income, and food indicators, revealing the evolving impact on food security. This research emphasizes the need for sustainable land use practices, incentivizing land preservation, and promoting diversified incomes to ensure food security, environmental resilience, and socio-economic stability in Bakalan Village and similar agricultural communities globally. Adaptive policies informed by such models are essential for addressing these multifaceted challenges effectively.
Effect of Growing Media Composition and Watering Intervals on the growth of Gmelina arborea Roxb seedlings
Authors: Fadilah Diah Rifdha , Zulkaidhah  , Rahmawati  , Wulandari Retno , Yusran  , Syahputra Gilang Ramahdhan
Published: January 2025

Gmelina arborea Roxb is one type of forestry plant that has the potential to be cultivated. This is because in addition to having a high economic value, Gmelina arborea Roxb is a plant that is able to grow in critical areas and has a short life cycle. In addition, Gmelina arborea Roxb is one type of wood that has high productivity, high economic value, has a wide natural distribution, has a large genetic variation, can be bred easily, easy to master cultivation techniques, and is resistant to pests and diseases. The purpose of this study was the effect of planting media composition and watering interval on the growth of Gmelina arborea Roxb seedlings. The study used a complete randomised design (RCD) factorial pattern consisting of two factors: The first factor: the composition of planting media, the second factor: watering interval. The results showed that the treatment of media composition and watering intensity treatment and the combination of treatments had a significant effect on the growth of gmelina seedlings. The treatment with the composition of 750 g soil and 250 g cocopeat with watering intensity once a day gave the best results for the growth of gmelina seedlings.
COLORINDO COM PALAVRAS: A IMPORTÂNCIA DA AUDIODESCRIÇÃO DAS CORES NO PROCESSO DE COLORAÇÃO PESSOAL PARA PESSOAS COM CEGUEIRA ADQUIRIDA E MEMÓRIA REMANESCENTE DE COR
Authors: Moresco Ademar Felipe Scherpinski
Published: January 2025

Em frente a um mundo visual onde a cor é compreendida como um elemento essencial, pessoas que perderam a visão em algum momento da vida enfrentam inúmeras adversidades, especialmente no universo da moda. Esta pesquisa propõe a coloração pessoal atrelada à audiodescrição como uma ferramenta que promove a autonomia de indivíduos com cegueira adquirida que possuem memória remanescente de cor. Com base em um questionário eletrônico, 160 participantes responderam a 6 perguntas sobre 10 cores diferentes, resultando em 10.357 adjetivos que descrevem as cores em questão, utilizando a sinestesia como referência. Esses adjetivos foram agrupados por semelhança, e os 3 maiores grupos foram apresentados como porcentagem nos resultados finais de cada questão. O processo revelou-se eficaz ao transformar elementos até então visuais em palavras que compõem vocabulários detalhados e coesos para a realização da audiodescrição das cores no processo de coloração pessoal, contribuindo para o avanço científico e social da inclusão e da acessibilidade na área de cores e coloração pessoal.
VARIAÇÃO E HARMONIA NA COLORAÇÃO PESSOAL PELA COMPARAÇÃO ENTRE TOM DE PELE E COR DE ÍRIS
Authors: Calhari Silvana Rodrigues Lopes
Published: January 2025

A coloração pessoal é um sistema de classificação das pessoas com base no tom de pele, olhos, cabelo e sobrancelha. A análise ocorre por meio da identificação das características de profundidade, intensidade e temperatura (PIT) presentes no rosto. Após a realização de atendimentos de coloração pessoal, percebeu-se que algumas pessoas apresentam harmonia entre as cores da sua cartela e o colorido da íris e outras não. O objetivo da pesquisa é identificar a variação e harmonia por meio da comparação entre tom de pele e cor de íris, com base na característica da temperatura. O método utilizado foi o estudo de casos múltiplos, por meio da análise de oito participantes, quatro exemplos de variação e quatro de harmonia. Os resultados indicam que a variação ocorre quando o tom de pele e a cor de íris de uma pessoa apresentam temperaturas diferentes, promovendo uma beleza policromática. A harmonia ocorre quando o tom de pele e a cor de íris de uma pessoa apresentam as mesmas temperaturas, promovendo uma beleza monocromática. Este estudo contribui para os profissionais de coloração pessoal por apresentar uma nova forma de se analisar o colorido das pessoas, levando em consideração o tom de pele e a cor de íris. Novos estudos são sugeridos.
COLORAÇÃO PESSOAL E O IMPACTO NA AUTOPERCEPÇÃO DE PESSOAS ALBINAS
Authors: Mahfuz Yara
Published: January 2025

O albinismo é uma condição genética caracterizada pela ausência de pigmentação na pele, cabelo e olhos. Pessoas com albinismo enfrentam diversos desafios físicos e sociais, como discriminação e preconceito, devido à sua aparência particular, o que pode acarretar em uma autopercepção negativa. O objetivo deste estudo é investigar o impacto da coloração pessoal na autopercepção de pessoas albinas. Ainda, visa identificar se o acompanhamento pós-coloração pessoal é relevante para que elas consigam implementar no seu dia a dia as ferramentas apresentadas durante o teste de coloração pessoal. O método é o estudo de casos múltiplos. Os resultados indicam que a coloração pessoal tem um impacto positivo na autopercepção de pessoas albinas, promovendo uma conscientização de individualidade, assertividade no uso das cores e mais segurança e confiança nelas. O acompanhamento pós consultoria de coloração pessoal se mostrou importante para o uso da cartela nas produções de looks diários. Novos estudos se fazem necessários não só com pessoas albinas, mas também com outras especificidades de pele como vitiligo, melasma, rosácea e acnes em alto grau.
DESENVOLVIMENTO DE UM PROTÓTIPO DE CÍRCULO CROMÁTICO DIGTIAL ADAPTADO AO SISTEMA COLORADD: O IMPACTO DA ANOMALIA DE PERCEPÇÃO CROMÁTICA NA CONSTRUÇÃO DA IMAGEM PESSOAL DE INDIVÍDUOS COM DALTONISMO
Authors: Caffeu Larissa
Published: January 2025

A percepção cromática humana é um fenômeno complexo, envolvendo princípios físicos e biológicos fundamentais que afetam diversas áreas da vida cotidiana, como arte, design e moda. Pessoas daltônicas enfrentam desafios significativos devido a dificuldades na distinção e identificação de cores, o que limita sua autonomia, especialmente na escolha e combinação de vestuário. A indústria da moda, que tem avançado na criação de roupas inclusivas para diversos tipos de deficiências, ainda negligencia as necessidades dos daltônicos, resultando em uma ausência de métodos padronizados para a identificação de cores que facilite sua inclusão. Este trabalho destaca a necessidade imperativa de desenvolver soluções inclusivas, propondo a integração do sistema ColorAdd com um protótipo de círculo cromático digital adaptado. A pesquisa apresenta um protótipo que tem como intuito ampliar a autonomia dos daltônicos na seleção e combinação de cores, avaliando o nível de conscientização atual sobre o daltonismo e a eficácia de métodos como o ColorAdd. A importância do projeto reside em sua capacidade de melhorar a qualidade de vida dos daltônicos, promovendo uma sociedade mais justa e inclusiva, e contribuindo para o avanço do conhecimento científico e tecnológico na área.
Culturas escolares: un abordaje desde la producción intelectual y los reportes de inspección técnico-escolar de Pedro Mora Beristaín en Veracruz 1902-1923
Authors: Pedroza Cervantes José Manuel , Sáenz Díaz Diana Karent
Published: January 2025

La reflexión que se esboza en torno al proyecto educativo de la primera década del siglo xx resulta de sumo interés por los cambios experimentados en los discursos y las prácticas pedagógicas, el perfil del profesorado, así como la organización escolar, dimensiones que estructuran y significan el proyecto educativo popular en Veracruz. El análisis de estas se realiza a través de la noción de culturas escolares, las cuales se asumen como un conjunto de proposiciones y disposiciones de carácter normativo, pedagógico, metodológico, contextual y sociopolítico en el contexto de los centros escolares (Bertely, 2019); todo ello a partir de las contribuciones intelectuales y profesionales del inspector técnico-escolar Pedro Mora Beristaín. Por lo anterior, nos interesa estudiar la vida del profesor al igual que sus quehaceres profesionales, ya que realizó diferentes aportaciones en dos proyectos educativos: 1) durante el Porfiriato bajo el paradigma de la educación moderna y el método simultáneo y 2) en el gobierno constitucionalista y el desenlace de los años veinte en el desarrollo de la educación popular. Desde luego, su activismo político-ideológico, sus contribuciones desde la prensa educativa, su práctica-docente y su papel como inspector técnico-escolar ayudan a visibilizar el panorama educativo en los espacios urbanos y rurales de Veracruz donde trabajó. Su trayectoria profesional permite el estudio de las rupturas y continuidades en el devenir histórico del proyecto educativo.
INTERVENÇÃO CORONÁRIA PERCUTÂNEA NO CONTEXTO DO IMPLANTE PERCUTÂNEO DE BIOPRÓTESE VALVAR AÓRTICA (TAVI): INDICAÇÕES, ESTRATÉGIAS TERAPÊUTICAS E DESAFIOS TÉCNICOS
Authors:   Instituto Dante Pazzanese de Cardiologia. São Paulo, SP, Brasil, Siqueira Dimytri Alexandre , Mangione Fernanda ,   Beneficência Portuguesa de São Paulo. São Paulo, SP, Brasil, Hermano Ogama Mickael ,   Rede D’Or, São Paulo. São Paulo, SP, Brasil., Esteves Vinícius ,   Rede D’Or, São Paulo. São Paulo, SP, Brasil., Barbosa Ribeiro Henrique ,   Instituto do Coração (InCor) da Faculdade de Medicina da Universidade de São Paulo. São Paulo, SP, Brasil
Published: January 2025

A presença de doença arterial coronária é bastante comum em pacientes com estenose aórtica (EAo) importante submetidos ao implante transcateter de válvula aórtica (TAVI). Nesse sentido, diagnóstico e manejo terapêutico mais apropriados são de extrema importância na prática clínica. Com a crescente expansão das indicações de TAVI a pacientes mais jovens e de menor risco cirúrgico, conhecimentos adicionais devem ser buscados para se identificar subgrupos de pacientes que mais se beneficiem da intervenção coronária percutânea (ICP) concomitante à TAVI (seja antes, durante ou após o tratamento percutâneo da EAo). Enquanto aguardamos por novas evidências, a tomada de decisão deve ser embasada em aspectos como idade, apresentação clínica inicial e localização e complexidade das lesões coronárias. No presente artigo, são revisados os principais aspectos relevantes ao tema, bem como relacionados à obstrução coronária, importante complicação periprocedimento de TAVI.
Using actigraphy to assess sleep characteristics
Authors: Trusov G. A. , Korobeinikova A. V. , Getmantseva L. V. , Bakoev S. Yu. , Lomov A. N. , Keskinov A. A. , Yudin V. S.
Published: January 2025

Research points to the importance of circadian rhythms for health; their disruptions are associated with various diseases. This has led to the development of circadian medicine, which focuses on using knowledge of physiological rhythms to optimize treatment and  diagnostic methods. Our article highlights the  role of  actigraphy, a non-invasive method for assessing sleep-wake cycles, in the study and diagnosis of  sleep. Actigraphs, wearable devices shaped like watches, use motion sensors to monitor activity, providing important data on sleep quality. Particular attention is given to the methodology for obtaining actigraphy data and the analysis of sleep parameters, which includes the  assessment of  total sleep time, sleep efficiency, and frequency of awakenings. The importance of accurate methodology and validated algorithms for  actigraphy data analysis is  emphasized through a  review of various sleep assessment algorithms and their application in clinical and research settings. Additionally, the paper explores the potential use of artificial intelligence, including machine and deep learning, to improve sleep data analysis. The conclusion emphasizes that despite the reliability of actigraphy for determining sleep phases, additional studies are needed to validate it in clinical use. This highlights the potential of actigraphy as an important tool in circadian medicine and sleep studies, which requires its further development and integration with new technological advances.
Identification of risk predictors of undesirable hemorrhagic phenomena during retinal surgery in patients with diabetes mellitus on hemodialysis
Authors: Oleshchenko I. G. , Mankov A. V. , Zabolotskii D. V. , Kuzmin S. V.
Published: January 2025

A patient with diabetes mellitus (DM) complicated by nephropathy and retinopathy has changes in hemostasis, which poses a serious problem during retinal surgery and anesthesia using regional blockades.

The aim. To determine the risk factors of undesirable hemorrhagic phenomena occurrence in DM patients being on programmed hemodialysis during regional anesthesia at the time of retinal pathology surgery.

Materials and methods. A retrospective analysis of medical histories (for 2021– 2023) was performed. Age, gender, DM type, ASA score, duration of renal replacement therapy, time after last and before next hemodialysis, insulin therapy duration, diabetic retinopathy proliferative stage, general blood test, creatinine, blood sugar, APTT, undesirable hemorrhagic phenomena during retrobulbar anesthesia were recorded. Spearman correlation analysis was used to assess the relationship between the studied signs and hemorrhagic complications.

Results. General blood test parameters evaluation revealed an average platelet count of 320 ± 47.5 × 109. Creatinine levels exceeded the norm by 5–7 times, which is typical for terminal chronic kidney failure (tCKF). APTT results before surgery did not go beyond reference values. The most significant correlations with an average positive relationship were established between the presence of hemorrhagic complications and the duration of the proliferative form of diabetic retinopathy (r = 0.67; p < 0.05), blood platelets number (r = 0.3; p < 0.05), creatinine level (r = 0.64; p < 0.05).

Conclusion. During retinal pathology surgery, the duration of diabetic retinopathy proliferative form, uremic syndrome severity and thrombocytosis degree may be factors of undesirable hemorrhagic phenomena occurrence in patients with tCKF on programmed hemodialysis during regional anesthesia.
Assessment of the pathways of the visual analyzer using diffuse tensor MRI and optical coherence tomography in patients with multiple sclerosis
Authors: Shvets L. V. , Iureva T. N.
Published: January 2025

Early diagnosis of  ophthalmic manifestations of  multiple sclerosis (MS) is  quite complicated.

The aim. To assess the degree of impairment of the pathways of the visual analyzer in patients with MS, taking into account the data of structural optical coherence tomography and magnetic resonance imaging.

Material and methods. Four groups of  patients were analyzed: three groups of MS patients with various changes in visual functions and a group of somatically healthy patients. Structural changes of  the  optic nerve were assessed according to OCT and magnetic resonance studies.

Results. A decrease in the thickness of the nerve fiber layer was found in groups 2 and 3 in the lower temporal sector – to 29–44 μm, in the upper temporal sector – to 30–33 μm, in the lower nasal sectors – to 11–18 μm. The data of groups 1 and 4 were comparable (p = 0.22). MR tractography in  groups  2 and  3 determined the  MRI picture of  rarefaction and signs of interruption of the pathways, respectively. MR spectroscopy at the level of the visual cortex revealed: a decrease in NAA/Cho in groups 2 and 3 by 13–23 % (the  data of  groups  1 and  4 were comparable); a  decrease in  NAA/Cr by  17  % in group 1, and by 23 % in groups 2 and 3, a decrease in Cho/Cr by 21 % in group 1, by 13.4 % – in group 2 and by 8 % – in group 3. At  the  level of  visual radiance, a  decrease was observed: NAA/Cho by  31.5  %  – in  group  1, by  39.5  % – in  group  2 and  by  50  % – in  group  3; NAA/Cr by  21  % – in group 1, by 32–35 % – in groups 2 and 3, and an excess of Cho/Cr by an average of 22 % in all groups.

Conclusion. The  data obtained indicate degenerative changes in  the  pathways of the visual analyzer not only in MS patients with partial optic nerve atrophy, but also in patients with no complaints and clinically pronounced visual impairment.
The effect of copper acetate on hepatocyte metabolism in vitro
Authors: Trukhan I. S. , Dremina N. N. , Shurygina I. A.
Published: January 2025

Background. Copper ions are necessary for maintaining basic physiological processes in the mammalian organism. However, their excessive absorption or accumulation in cells can lead to the development or exacerbation of various pathological processes. The  cytotoxic and  genotoxic effects of  high concentrations of  copper compounds are  currently well studied in  various cell cultures, whereas the  effect of non-toxic amounts of copper ions on physiological processes in cells, including during their cultivation, has been extremely poorly studied.

The aim of the study. To investigate the effect of copper ions on changes in the intracellular amount of mitochondrial cytochrome C oxidase and glutathione synthetase.

Materials and methods. A primary culture of hepatocytes was obtained, which was exposed to copper acetate at a concentration of 200 µg/ml in terms of copper content for 24 hours. After fixation, the samples were stained immunocytochemically using antibodies to  cytochrome  C oxidase (CcO) subunit  I and  glutathione synthetase (GS).

Results. In  hepatocyte culture, a  significant increase in  the  intensity of  fluorescent staining of the two analyzed enzymes was demonstrated both after 6 hours and  after  24  hours of  exposure to  copper ions, which indicates a  change in  their number in  cells. At  the  same time, the  increase in  the  amount of  CcO was more intense in the first 6 hours of incubation with a microelement, whereas in the next 18 hours, changes in the intracellular content of CcO were less pronounced. The increase in the intensity of the GS fluorescent stain was more active and was observed throughout the entire cultivation period.

Conclusion. From the  results obtained, it  can  be concluded that copper ions in  non-toxic concentrations are  able to  influence key indicators of  cell viability in culture by changing the amount of one of the main energy metabolism enzymes and the enzyme that provides synthesis of the most important low-molecular antioxidant glutathione.
Ixodes ticks as carriers of human and animal babesiosis agents in the Baikal region
Authors: Suntsova O. V. , Rar V. A. , Meltsov I. V. , Lisak O. V. , Doroshchenko E. K. , Kozlova I. V.
Published: January 2025

Background. Piroplasmosis (babesiosis and theileriosis) is a group of natural focal infectious diseases of  humans and  animals caused by  intraerythrocytic parasites transmitted predominantly by ixodid ticks. In the Baikal region, despite the widespread foci of babesiosis and theileriosis, the data about these pathogen vectors is fragmentary.

The aim. To identify human and animal babesiosis vectors, study various Babesia spp. tropism to ixodid ticks common in the Baikal region.

Materials and methods. A total of 3,239 specimens of I. persulcatus, 1,795 specimens of D. nuttalli and 729 specimens of H. сoncinna ticks collected in natural habitats of the Baikal region from 19 districts of the Irkutsk region and six districts of the Republic of Buryatia, as well as 5 specimens of D. nuttalli ticks removed from horses were examined for the presence of Babesia spp./Theileria spp. DNA. For detection and typing of Babesia and Theileria, a nested PCR with genus- and species-specific primers corresponding to  18S  rRNA gene region was used. Selective sequencing of samples was performed to study the genetic diversity of the identified pathogens.

Results. Babesia spp. DNA was detected in three species of ixodid ticks in Irkutsk region and in one species in the Republic of Buryatia. In I. persulcatus ticks B. microti US-type, B. venatorum, B. crassa-like and a unique Babesia sp. Irk-Ip655 were found. DNAs of B. crassa-like, B. motasi-like and Babesia spp. were detected in H. concinna ticks. DNAs of Babesia spp. And T. equi were found in D. nuttalli ticks.

Conclusion. Vectors of  both human and  animal babesiosis pathogens were  detected in the Baikal region. Tropism of B. microti US-type and B. venatorum in relation to I. persulcatus ticks was established. The establishment of specific relations between other species of Babesia and Theileria and vector ticks in the Baikal region will be continued.
Epigenetic modulation in medicine: Regulation of gene expression in the context of pathogenesis and therapy
Authors: Omarov M. A. , Mulyukov A. R. , Khalitov R. V. , Safarov S. I. , Ayupova G. U. , Demianenko O. N. , Butenko V. V. , Safronova A. A. , Zainetdinova R. R. , Ianturina O. Yu. , Miroshnikov A. A.
Published: January 2025

Epigenetics plays a critical role relative to other branches of genetics, as it makes it possible to regulate gene expression without changing the nucleotide sequence of DNA molecules. This process allows cells to respond to external signals and adapt to  changes in  the  environment while keeping their genetic information intact. The  main mechanisms of  epigenetic regulation include DNA methylation, posttranslational modifications of  histones, chromatin remodeling and  regulation through non-coding RNAs. These processes play a key role in fundamental biological processes such as cellular differentiation, organismal development, and adaptation to environmental conditions.

Disturbances in epigenetic mechanisms can lead to various pathologies, including cancer, neurological and  autoimmune diseases. Understanding the  mechanisms of  epigenetic regulation opens new avenues for  the  development of  targeted therapies that can correct abnormal epigenetic profiles without changing the DNA structure itself.

In  recent years, the  development and  application of  innovative technologies, such  as  the  CRISPR/Cas9 genome editing system, have significantly expanded the ability to study epigenetic mechanisms and their relationship with diseases. These technologies allow not only a deeper understanding of epigenetic changes, but also the development of new therapeutic approaches, especially in the field of oncology. Research in  epigenetics is  also focusing on  the  interaction between epigenetic changes and the immune system, which opens new perspectives for the development of immunotherapies. The search for new markers of epigenetic disorders and therapeutic agents may lead to the development of individualized treatments that take into account the unique epigenetic profile of each patient.

The role of epigenetic modifications in the development of diseases and the creation of new therapeutic strategies cannot be overestimated. Recent research in this area is revealing the potential of epigenetic approaches to treat a wide range of diseases, ushering in a new era in medicine where understanding and correcting epigenetic changes will be the key to effective treatment.
High seroprevalence to SARS-CoV-2 among healthcare and non-healthcare workers of the ophthalmology center
Authors: Palyanova N. V. , Chechenin M. G. , Trunov A. N. , Sobolev I. A. , Shestopalov A. M.
Published: January 2025

Background. The pandemic of COVID-19 raised safety concerns for healthcare workers while non-medical personnel were left unattended. Comparing the levels of seroprevalence to SARS-CoV-2 and vaccination in different employee groups will allows us to assess the risk of infection and develop a strategy to minimize the spread of infections in medical institutions in future.

The aim. To identify the level of seroprevalence to SARS-CoV-2 for seven groups of medical center workers. Methods. The seroprevalence to SARS-CoV-2 was analyzed in 361 employees of the ophthalmology center in mid-2021. Data on the level of specific IgM and IgG antibodies were compared with questionnaire, including occupation data.

Results. Depending on occupation, workers were divided into seven groups. The average seroprevalence rate for all employees was 82.3 %, and the percentage of vaccinated employees was 27.4 %. The lowest level of seroprevalence was found in the group of maintenance staff (55.0 %) which is significantly lower (p ˂ 0.05) than in the groups of doctors (84.4 %), nurses (85.6 %), administrative stuff (82.6 %) and cafeteria stuff (77.7 %). The seroprevalence rate for cleaning staff was 84.6 % and for pharmacy workers it was 80 %. The highest vaccination coverage was among doctors – 50.0 %, the lowest was among cafeteria and kitchen staff – 7.4 %.

Discussion. We believe the high seroprevalence is associated with asymptomatic spread of SARS-CoV-2.

Conclusions. High seroprevalence was among doctors and nurses, pharmacy workers, canteen workers, cleaners, as well as administration workers. Anti-epidemic measures for these groups will reduce the spread of  infectious diseases and help retain staff during the seasonal increase in incidence.
Sports tourism strategies in Cabanatuan city: A sustainable developmental framework
Authors: Elizabeth D. S. Eduardo  , Dulce Amor S. Padilla
Published: January 2025

This study develops a sustainable sports tourism framework tailored for Cabanatuan City, positioning it as a prominent destination aligned with the National Tourism Development Plan (NTDP) 2023-2028. Focusing on sports facilities, community engagement, and sustainable practices, this research evaluates current tourism assets, identifies improvement areas, and proposes strategies to attract local and international visitors. Utilizing a descriptive quantitative approach, data were gathered from sports facility managers and sports enthusiasts through surveys and analyzed statistically. Findings reveal that sports tourism holds strong economic and social potential for Cabanatuan, with community-centered strategies and sustainability initiatives highly valued by stakeholders. However, environmental development needs further emphasis. The study's framework provides a strategic path for Cabanatuan to realize sustainable growth in sports tourism, with future work focused on refining environmental practices. This approach not only strengthens the local economy but also contributes to social and environmental well-being, aligning with key Sustainable Development Goals.
Data analysis and visualization of electric vehicle engineering
Authors: Aditya Gaurav Gupta  , Aryan Gaurav Gupta  , Michelle Tashi Wongmu Bhutia
Published: January 2025

We have visualized data using Excel to understand the relationship between battery chemistries and capacity. Examined Python code for tuning a Proportional – Integral – Derivative (PID) controller to understand its role in improving control accuracy. The challenges and benefits of PID tuning are discussed, highlighting the importance of precise tuning for optimal performance, efficiency, and safety. Analysing the impact of various battery form factors, including cylindrical, pouch, and prismatic options, on system cost, safety, and durability. Furthermore, the paper explores design trade-offs in electric vehicle development, emphasizing the need for balancing competing parameters such as performance, durability, and cost-effectiveness. The characteristics of various battery form factors (cylindrical, pouch, and prismatic) and Light Detection and Ranging (LiDAR) sensors (mechanical, solid-state, and hybrid) are compared, providing insights into their suitability for different applications. Overall, this article offers a comprehensive overview of the intricate relationships between battery chemistries, PID controllers, and design trade-offs in the development of efficient and sustainable electric vehicles. Conducted a comprehensive cost-benefit analysis for different LiDAR sensor models, comparing mechanical scanning, solid-state, and hybrid LiDAR sensors, with a focus on durability, scanning speed, and cost implications. Beside the aforementioned, we have also presented technical findings in a concise format using tables, aiding the engineering division in making informed decisions for various projects.
Strategic procurement practices in healthcare organizations and their impact on Medicaid and Medicare cost containment
Authors: Adeseun Kafayat Balogun  , Helen Ayodimeji-Alaba  , Kaosara Temitope Adebayo  , Oluwabanke Aminat Shodimu
Published: January 2025

Strategic procurement in healthcare organizations has emerged as a critical factor in addressing the escalating costs within Medicaid and Medicare programs. This comprehensive review synthesizes current literature and empirical evidence on innovative procurement practices and their impact on healthcare cost containment. Through extensive analysis of procurement transformation across healthcare organizations, this review identifies key trends in value-based purchasing, digital integration, and supply chain optimization. Findings indicate that healthcare organizations implementing strategic procurement practices achieve substantial cost reductions in medical supplies and equipment while maintaining or improving quality standards. The integration of artificial intelligence and blockchain technologies in procurement processes has demonstrated particular promise, with early adopters reporting enhanced transparency and reduced administrative burden. This review also reveals significant barriers to implementation, including organizational resistance, regulatory constraints, and technical infrastructure limitations. The findings suggest that successful procurement transformation requires a systematic approach combining technological innovation, organizational change management, and policy adaptation. These insights provide valuable guidance for healthcare administrators, policymakers, and researchers working to optimize healthcare resource allocation and control costs in public health insurance programs.
«Развитие коллекций» как концептуальная модель в современных музейных исследованиях
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Balash Aleхandra N.
Published: January 2025

The research is dedicated to comprehensive analysis of the current museological concept of collection development. The reasons of origination of this concept, its genesis through the research of Dutch museologist Piter Van Mensh, as well as further elaboration and popularization of the concept among professional community in the first quarter of XXI century have been examined. Collection development is analyzed as a relational and dynamic strategy, which corresponds to a socio-cultural mission of a contemporary museum providing access to cultural heritage. The museum collection, as an agent, and correlation between this museological model and the concept of collection development are discussed. The method of collection reinterpretation is considered in the context of revealing its original meaning, its volatile status in museological research and through direct interaction between the community of origin and interested communities.