bluuebunny/crossref_metadata_2025 huggingface dataset:
Yöneticinin Hazine Dairesi: İtibar Yönetimi Selim-Nâmeler Ekseninde İtibar Yönetimine Bakış
Authors: KARASAR Şahin , ÇİÇEK Meltem
Published: October 2019

Halkla İlişkiler faaliyetlerinin bel kemiği olan itibar yönetimi, “güven” üzerine tesis ettiği saygınlık sayesinde marka değerini arttıran unsurların başında gelmektedir. İtibar yönetimi çatısı altında şekillenen bu çalışma, edebiyat eseri aracılığıyla Osmanlı Döneminde Halkla İlişkilerin varlığına dikkat çekmeyi ve Selim-Nâme türünde yazılan eserlerin bir Halkla İlişkiler aracı olarak da değerlendirilebileceğini ortaya koymayı amaçlar. Edebiyat eseriyle, tarihî olaylar hakkında bilgi vermek, itibarı yönetmek için sıklıkla tercih edilen bir yoldur. Yöneticilerin icraatlarının paylaşıldığı; Orhun Yazıtları ve bunun gibi birçok eserde bu izler görülür. Çalışmada; bu noktadan hareketle Yavuz Sultan Selim döneminde yazılan Selim-Nâme’ler, Sultan Selim’in yönetim becerileri ekseninde itibar yönetimi bağlamında yorumlanmıştır. Örneklemde yer alan Selim-Nâmede; I.Selim’in şehzadelik günleri, yöneticilik özellikleri, tahta çıkışı, savaşları ve zaferleri ayrıntılı olarak anlatılarak kamuoyu, dönem hakkında bilgilendirilmiş; olayların neden ve sonuç ilişkileri ortaya konulmuştur. Tüm bunlar, Selim-Nâmeler’in  itibar yönetimi ekseninde adı konulmamış bir Halkla İlişkiler çalışması gerçekleştirdiğini düşündürmektedir. Çalışmanda; Celal-zâde Mustafa tarafından kaleme alınan Selim-Nâme incelenerek eser, Machiavelli’nin Prens eserinde yer alan yöneticilik özellikleri noktasında betimleme yöntemiyle yorumlanmıştır. Disiplinler arası bir yaklaşımla Selim-Nâme’ler üzerine daha önce benzer bir çalışma yapılmadığından araştırmanın literatüre katkı sağlayacağı düşünülmektedir.  
Genç İşsizliğin Yetişkin İşsizlik ile Karşılaştırmalı Analizi: Türkiye için Kalman Filtresi Yöntemi ile Dinamik Bir Uygulama
Authors: KARAHAN DURSUN Pınar , ÇAĞLARIRMAK USLU Nilgün
Published: October 2019

Genç işsizliğin ekonomik konjonktür hareketlerinden ve son yaşanan küresel finans krizinden yetişkin işsizliğe göre daha fazla etkilendiği, uluslararası yazında tartışılmaktadır. Bu çalışmada, global makroekonomik sorunların başında gösterilen genç işsizliğin boyutları yetişkin işsizlik ile karşılaştırılmalı olarak incelenmiş olup, küresel finans krizinin genç işsizlik üzerindeki göreli etkisi dinamik olarak analiz edilmiştir. Ampirik analizde, konjonktürü temsilen ekonomik büyüme oranlarının genç ve yetişkin işsizlik oranları üzerindeki etkileri 2006:Q1-2017:Q4 dönemi için ARDL modeli ve Kalman Filtresi yöntemi kullanılarak Türkiye için incelenmiştir. Elde edilen sonuçlar, büyümenin genç işsizlik üzerinde daha yüksek negatif etkisinin olduğunu ve genç işsizliğin, küresel finans krizi dönemine denk gelen ekonomik daralma dönemlerinden daha fazla etkilendiğini göstermiştir. 
Sartre ile Kierkegaard’un Varoluşçu Özneleri Dijital Özneye Karşı: Öznellik Egemen İdeolojiyi Yenebilir mi?
Authors: KARHAN Pınar
Published: October 2019

Günümüz toplumlarında “özne” kavramının ne olduğu ve işlevi, içinde yaşadığımız dünyayı anlayabilmek açısından oldukça önem taşımaktadır. Her yeni iletişim aracıyla değişik biçimlerde egemen ideolojinin içinde oluşan “özne” sistemin devamını sağlayan bir işleve sahiptir. Dijital iletişim teknolojisinin tüketici ve bağımlı öznesi bunlardan biridir. Tanrı kavramına farklı açılardan bakan varoluşçuluğun önde gelen iki ismi Sartre ve Kierkegaard ise özneye sorumluluk yükleyerek özgürlük vaadinde bulunur. Bu çalışmanın amacı varoluşçuluğun etken öznesi ile dijitalin edilgen öznesini karşılaştırmak, varoluşçuluğun mutsuz insanın reçetesi olup olamayacağı tartışmasını başlatmaktır. 
Association Between Severity of Anaphylaxis and Co-occurrence of Respiratory Diseases: A Systematic Review and Meta-analysis of Observational Studies
Authors: Tejedor-Alonso MA , Farias-Aquino E , Pérez-Fernández E , Moro-Moro M , Rosado-Ingelmo A , Alberti Masgrau N , Pérez-Codesido S , Privitera-Torres M
Published: October 2019

Background: Asthma is very prevalent in all grades of severity of anaphylaxis. Asthma and chronic obstructive pulmonary disease (COPD) have been associated with the severity of anaphylaxis. Objective: We carried out a systematic review and meta-analysis to assess the influence of respiratory diseases on the severity of anaphylaxis. Methods: We searched PubMed/MEDLINE, EMBASE, and the Web of Science for observational studies. The target studies were those that compared the severity of anaphylaxis between patients who had or did not have respiratory diseases. Results: A total of 13 studies assessed the severity of anaphylaxis in respiratory disease. Respiratory disease increased the severity of anaphylaxis (OR, 1.87; 95%CI, 1.30-2.70), as did asthma (OR, 1.89; 95%CI, 1.26-2.83). For the meta-analysis of all studies (adjusted and nonadjusted), COPD increased the severity of anaphylaxis (OR, 2.47; 95%CI, 1.46-4.18). In the case of asthma studies, only 1 study assessed the influence of severity of asthma on severity of anaphylaxis. Conclusions: Evidence showing that respiratory disease increases the severity of anaphylaxis is low to moderate, although studies do not usually assess the importance of severity of asthma.
A comparative study on safety and efficacy of tolperisone with etodolac and thiocolchicoside with etodolac in patients of acute low back pain with musculoskeletal spasm
Authors: Garg Tanu , Yadav Vijay K.
Published: October 2019

Background: Low back pain is one of the most common health problems in society which leads to considerable disability, loss of work days, and puts a huge burden on socioeconomic and healthcare system. It is often associated with musculoskeletal spasm. The aim of the study was to compare the efficacy and safety of tolperisone and thiocolchicoside in combination with etodolac in patients of acute low back pain associated with musculoskeletal spasm.Methods: it was a prospective, randomized, open label study which included patients of either sex between age 18-50 years of acute low back pain with musculoskeletal spasm. Patients were allocated in two groups. Patients in ‘Group A’ were given tolperisone 150 mg + etodolac 400 mg twice a day and patients in ‘Group B’ were given thiocolchicoside 4 mg + etodolac 400 mg twice a day. Efficacy of two drugs was assessed by decrease in finger to floor distance (FFD), decrease in pain as per visual analog scale (VAS) and global assessment of efficacy of treatment by physician. Follow-up of the patients was done on day 3 and 7 of treatment. Various side effects reported by patients in both the groups were also recorded and compared.Results: Both tolperisone and thiocolchicoside caused significant decrease in FFD, reduced pain score thus indicating decrease in pain and spasm. Side effects reported in both groups were mild and did not result in discontinuation of therapy.Conclusions: Tolperisone was found to have efficacy similar to that of thiocolchicoside though number of side effects reported was more with tolperisone.
Comparative study of safety and efficacy of pregabalin and gabapentin in management of neuropathic pain associated with chronic lumbar radiculopathy
Authors: Shaikh Huzaif , Syed Maaz H. , Khan Imran N. , Mubeen Faheem
Published: October 2019

Background: Chronic lumbar radiculopathy a clinical condition in which there is back and leg pain associated with sensory, reflex, or motor deficits in the area of nerve root distribution lasting for more than 12 weeks. The prevalence of lumbar radiculopathy has been reported to be 5.3% in men and 3.7% in women. Pregabalin and gabapentin, which fit in to a new category of drugs called as alpha-2-delta (α2δ) modulators, have been discovered to be effective in the treatment of neuropathic pain related with multiple conditions. So this study was done to compare safety and efficacy of pregabalin and gabapentin in management of pain associated with chronic lumbar radiculopathy.Methods: This was a randomized two arm comparative prospective study. Total 160 patients were enrolled and randomized equally into 2 groups. Group A patients were given capsule pregabalin 75 mg two times a day orally, Group B patients were given tablet gabapentin 300 mg two times a day. Pain intensity was assessed at the start of study i.e. at baseline (0 week), at 6 weeks and at 12 weeks of starting the treatment using numeric pain rating scale.Results: There was significant reduction in pain at the end of 12 weeks in both the groups (p<0.0001), but there was no significant difference between these two groups. The incidence of adverse effects was also more in group A.Conclusions: Both the drugs are having comparable efficacy but gabapentin is more tolerable in such cases.
Analysis of spontaneous individual case safety reports reported at adverse drug reaction monitoring centre: tertiary care teaching hospital in South India
Authors: Bhuvaneshwari E. , Chakradhar T. , Sravani M.
Published: October 2019

Background: Drugs are double edged weapons, they are used in treatment of the patients but in return can harm as well. The safety of drug prescribing has become a need of the hour topic in medicine. Safety monitoring of patients via Pharmacovigilance tool has become an integral part of pharmacotherapy. This study has been undertaken to analyze the various individual case safety reports including the Special situation cases of medicational error and over dose and to promote the reporting of adverse drug reactions (ADRs) among the healthcare professionals (HCPs).Methods: A retrospective non-interventional observational study was done for indexed period of six months at AMC-PvPI under Osmania Medical College and General Hospital. The reported individual case safety reports (ICSRs) are evaluated on basis of demographics of age and gender, seriousness criteria, outcome parameters and causality assessment of suspected drug (s) and suspected ADR/AE (s) as per the ICH guidelines and WHO causality assessment scale.Results: A total of 177 ICSRs are reported out of that 137 were ADRs, 36-medication error cases and 4-cases of over dose. The incidence of ADRs in females are high compared with males was identical. The occurrence of ADRs in adult patients (61%) was significantly higher than other age groups. Of total ADRs, most of them were with analgesics (26%) and highly reported system organ classification was CNS. Overall, 79% patients were recovered from ADRs.Conclusions: The results depicted an insight to the HCPs on the importance of monitoring and reporting of ICSRs. Our study results emphasized need to roll out a pharmacovigilance practice tool to ensure the safe use of drugs for better Pharmacotherapy and development of pharmacogenomic studies.
Knowledge and attitudinal survey of drug promotional literature among second year undergraduate students: a questionnaire based study
Authors: Agrawal Ratna , Jaiswal Mahendra Kumar , Sharma Sanat Kumar , Sharma Raj
Published: October 2019

Background: Promotion of drugs has been increased enormously with the advancement of technology and use of internet and media etc. Pharmaceutical manufacturers spend vast amount of money on promotion usually through medical representatives by providing printed advertisements. But, it has been seen that these printed advertisements are not up to the mark usually, they either overemphasize the efficacy or hide the safety profile for the sake of company’s profit. All these promotional activities influence the prescribing pattern of doctors. So, the present study has been conducted to assess the knowledge and attitude of second year undergraduate students about promotional literature and to train them accordingly for improving the prescribing behaviour.Methods: A questionnaire based study containing 9 questions was conducted in 110 second year undergraduate students after taking informed consent. Statistical analysis was done by using descriptive statistics by graph pad prism version 6.01.Results: Among respondents 60 (61.2%) were males and rest 38 (38.8%) were females. 50 (51%) of the respondents have chosen Indian pharmacopoeia as a trusted source of information followed by others. Most common factor affecting the prescribing attitude was reported as updates from clinical trials 49 (50%) followed by prescriber’s knowledge. Most important intervention taken to stop misleading drug promotional activities has been reported as formulation of strict regulation by the health care authorities against any misleading promotion.Conclusions: Promotional activities by manufacturers influence the attitude and prescribing pattern of doctors. So, it is important to teach the students about their rational use by critically analysing it.
Fetal birth weight, a challenge to the mother and simplest marker for fetal maturity: a study in new rural hospital setup
Authors: Nagarashi Rajashree Dattatreya , Durvasula Lakshmi Swapna
Published: October 2019

Background: The birth weight is an important factor which the obstetricians have to give due importance when contemplating elective induction of labor before 40 completed weeks. It is a single most important determinant for survival, growth and development of infant. It reflects the health status of the mother during adolescence and pregnancy and also the quality of antenatal care. It is well known that there is a co-relation between weight of the fetus and the length of the gestation and other various factors. This study looks into the various factors influencing the fetal birth weight and length of gestation and what is its relative importance to the viability of developmental chances of premature infants and also infants born at term. Objective was to study the effect of various maternal factors like maternal age, parity, maternal weight, gestational age on fetal birth weight.Methods: 176 participants with term pregnancies were studied under three independent variables viz gestational age, maternal age and maternal weight that had effect on the fetal birth weight in two groups - primipara and multipara and reported by statistical analysis.Results: The independent variables gestational age and maternal weight showed a statistically significant correlation (p <0.05) with fetal birth weight in both the groups. Whereas the variable maternal age didn’t have any statistically significant effect (p >0.05) on the fetal birth weight in the study.Conclusions: Primipara had more pronounced correlation with fetal birth weight than multipara in the variable gestational age. The maternal weight affected fetal birth weight equally in both the groups. And maternal age had no effect on fetal birth weight in either groups.
Total laparoscopic hysterectomy: an experience at a tertiary care hospital
Authors: Rentiya Fatma M. , Desai Ajesh N.
Published: October 2019

Background: This study is aimed to review indications, demographic data of patients, clinical outcomes and safety of total laparoscopic hysterectomy.Methods: This is a prospective observational study of total 150 patients who underwent total laparoscopic hysterectomy (TLH) from 1st June 2017 to 30th November 2018 in GMERS Civil Hospital Sola.Results: ~45% patients were between 40-50 years age group; 60% patients had 2 or more deliveries; commonest indication was symptomatic adenomyosis ; uterine size in ~57% of patients were up to 6 weeks; duration of surgery in ~91% of patients <120 minutes; intraoperative blood loss in all cases <200ml; no intra-operative and postoperative complications were encountered.Conclusions: TLH is safe procedure with minimal blood loss, minimal postoperative pain and discomfort and shorter duration of hospital stay when performed via expert hands.
Comparative evaluation of different cost effective ovulation induction drugs and their effect on follicular growth, endometrial thickness and pregnancy outcome
Authors: Narayanan Madhumithaa , Jahaan Uruj , Gupta Neena
Published: October 2019

Background: Ovulatory dysfunction is a common cause of female infertility, occurring in up to 20 - 30% of infertile women. The most commonly prescribed ovulation drugs are clomiphene citrate (CC), tamoxifen, aromatase inhibitors (such as letrozole) and gonadotropins. Objective of the study was to evaluate the efficacy of clomiphene citrate, letrozole and tamoxifen for ovulation induction in anovulatory infertility.Methods: Randomized open label interventional clinical trial. Patients were randomized to 3 drug groups. After baseline investigations, they were subjected to ovulation induction and then USG monitoring of follicular growth and ovulation. The primary outcome measured was occurrence of conception. Secondary outcome was effect on endometrial thickness and ovulation rate.Results: In the study, letrozole group showed 100% mono-follicular response. Mid cycle endometrial thickness in about 17% of cases in CC group is ≤8 mm. But all the cases in tamoxifen and letrozole group have ET >8 mm. This difference is statistically significant. The ovulation and conception rates are highest in letrozole group but the difference was not statistically significant.Conclusions: Letrozole produces higher mid cycle endometrial thickness, 100% mono follicular development than clomiphene and tamoxifen. This difference is found to be statistically significant. Ovulation rate and conception rate is highest in letrozole group. But there is no statistically significant difference among the three drugs.
Prognostic significance of initial management of childhood diarrhoea in rural areas: an observational study
Authors: Gohiya Poorva , Shrivastava Varsha , Dwivedi Rashmi
Published: October 2019

Background: To identify current evidence in order to guide scaling up of initial management of diarrhoea among children of age group 2-60 months in rural areas of the country.Methods: This hospital based cross sectional study included all children 2 months to 60 months of age admitted with chief complains of loose stools in the last 7 days over a period of one year. A pre-tested questionnaire was used as the data collection tool and face to face interviews were conducted on mothers of children.  All the data were analyzed using IBM SPSS version 20 software. Chi-square/Fisher Exact/ Student t-test and ANOVA test has been used. Significance was assessed at 5%.Results: Data showed the use of antibiotic in 55.9% cases, IV fluids in 50.3%, ORS in 6.7%, zinc in 2.0% and blood transfusion in 13.8% cases as an initial management of diarrhoea in peripheral health care centers. Of these, 37.6% cases were severely dehydrated, and 8.14% cases were in shock at the time of admission. 10.1% mothers did not intervene in the first 3 days of the disease whereas 45.2% consulted some health care center only in the later part. 4.5% cases expired after admission of which 69% were malnourished.Conclusions: This study summarizes the importance of initial management of a child with diarrhoea in defining the further course of the disease and also the failure of effective promotion and propagation of the most appropriate and cost-effective therapy (ORS and Zinc) for diarrhoea in this part of the country. Pre-existing malnutrition further complicates the situation.
Rhinoentomophthoramycosis: Madras ENT Research Foundation experience
Authors: Natarajan Kiran , Gajapathy Sowmya , R. Swathi , Soodimuthu A. , Kameswaran Mohan
Published: October 2019

Rhinoentomophthoramycosis is a rare tropical fungal infection affecting the nasal cavities and the subcutaneous  tissues. The most common causative organism is Conidiobolus coronatus followed by Basidiobolus. In our institution, two patients with Rhinoentomophthoramycosis were seen over a ten year period and were treated successfully with anti- fungal therapy. Rhinoentomophthoramycosis has to be considered in the differential diagnosis of a nasal granuloma or subcutaneous swellings in the face or neck.

 
Study of role of caudal epidural steroid in management of low back pain in Malayalam patients
Authors: Rajasekharan Jayakrishnan
Published: October 2019

Background: 85 patients of different age groups were treated with caudal epidural steroid injection for the management of low back pain. As low back pain is quite common in adults.

Methods: X-ray, MRI of the lumbar region was studied. Degree of the pain was assessed by VAS (visual analogue scale) scale, study of Lumbo-sacral joint was studied to know the causes of low back pain (LBP).

Results: As per the MRI study classification LBP was classified as, 16 (16.3%) had Acute back pain without any cause, 14 (14.2%) had spondylolithesis having symptoms of claudication with low back pain. 26 (26.5%) had stenosis of Lumbar canal with symptoms of claudication 42 (42.8%) had disc degeneration with or without root radiation having complaint of back pain and leg pain. The improvement as per VAS scale was from 1 week to 3 months in the management of LBP.

Conclusions: This pragmatic approach to various causes of low back pain managed with epidural steroid injection will be useful to orthopedic surgeon to treat such pain efficiently because back pain becomes common factor as age advances due to resorption or degenerative factors andcurvatures of vertebral column becomes less pronounceds. 
Clinical and radiological outcome of distal femoral fractures treated by distal femoral locking compression plate
Authors: Khajotia B. L. , Shekhawat Vikrant , Chauhan Shakti , Bhatiwal Sunil
Published: October 2019

Background: Distal femoral fractures represent a challenging problem in orthopaedic practice. Open reduction with internal fixation has replaced previous trends of closed conservative management and external fixation. Distal femoral locking compression plate (DF-LCP) provides both locking and compression screw fixation of the femur shaft. This study was conducted to assess the clinical and radiological results of distal femoral fractures treated with DF-LCP.

Methods: It was a prospective study on 90 cases. Fracture patterns AO type A and C were considered. Lateral approach was used as standard surgical technique. The total follow up period was 6 months .Functional and radiological results were evaluated using Neer’s score.

Results: The series consisted of 64 males and 26 female patients with mean age 40.56 years. Road traffic Accident (68%) was the commonest mode of injury. Most were closed fractures. Wound infection was seen in 4 patients. Average flexion at knee joint was 117°. 100% union rate was observed with an average union time of 14.3 weeks. NEER’s score was excellent in 44, good in 32, fair in 10 cases and poor in 4 cases.

Conclusions: DF-LCP is an important armamentarium in treatment of distal femur fractures especially when fracture is closed, severely comminuted and in case of osteoporosis.
A study of clinicoradiological and functional outcomes of intramedullary nailing in diaphyseal radius ulna fractures
Authors: Tank Parag M. , Shah Yash S. , Dave Rutvik D. , Patel Vijay J.
Published: October 2019

Background: The aim of this study was to evaluate the results of intramedullary nailing in diaphyseal fractures of radius and ulna in age group of 10 to 49 years and to understand its clinicoradiological and functional results.

Methods: This is a retrospective case series study of forearm bone fractures and the selected management for the same over a period of 3 years. We chose the cases in which intramedullary nailing was the treatment modality which were followed up over a period of minimum 6 months. Patients with galeazzi variety, monteggia variety, pathological fracture or non-union after previous surgery were excluded. The outcomes were then evaluated with disabilities of the arm, shoulder and hand (DASH) score, Green and O’Brien score, and Grace and Eversmann functional outcome score.

Results: Of the 22 patients, 10 patients had excellent functional outcome according to Grace and Eversmann score, 7 patients had good outcome, 4 patients had acceptable while 1 was unacceptable. Green and O’Brien also had similar results, except that patients among fair category were 3 and poor category were 3. The mean DASH score was 16.2.

Conclusions: This study shows that closed method for fixation by intramedullary nailing of both bone forearm fractures leads to excellent to good functional outcomes (according to DASH score, Green and O Brien, and Grace and Eversmann score) with less complications. In 6 months follow up x ray there is radiological union in all cases with no angulation, malunion or non-union. 
Early onset osteoarthritis knee in premature menopausal women
Authors: Sharma Anil Kumar , Tiwari Smita Sharma , Dixit Alka
Published: October 2019

Background: Women with early menopause medical (disease) or surgical (hysterectomy) are having postmenopausal symptoms after a variable period. Osteoarthritis (OA) strikes women more often than men and it increases in prevalence, incidence and severity after menopause. The present study was done to evaluate early onset osteoarthritis knee in premature (early) menopausal women.

Methods: We have studied 160 women with early menopause (before 40 yrs of age) developing symptoms and well established osteo arthritic knees. We have studied various factors with early menopause. The data was analysed using SPSS software version 22.

Results: In our study 138 cases (86.25%) were surgical menopause (hysterectomy) and 22 cases (13.75%) were medical menopause where definite cause was not obvious. An early onset knee pain was noted in 1 to 2 years. But late OA was noted after 6 to 7 years of menopause. Effective treatment was wanted by majority of the patient from the point of view of post-menopausal osteosaropaenia and physiotherophy. Even in urban population erratic treatment was maximum (75%). Dysfunctional uterine bleeding, fibroid or severe intractable infection appeared be the most common indication for hysterectomy.

Conclusions: We concluded that with better awareness of menopause, effective regular treatment and physiotherapy can herald the process of osteoarthritis. The difficulties were mainly developed early because of lack of awareness, no effective regular treatment and physiotherapy. Pain is the starting feature which may continue to severe disability later on.
Bi-columnar fixation of displaced distal humeral metaphyseal fractures in children: functional outcome assessment of 100 fractures
Authors: Gouse Mohamad , Muthulingam Manoharan , Rangarajan Nandakumar
Published: October 2019

Background: Supracondylar fractures of the humerus are one of the commonest fractures encountered around the elbow in children. The treatment of these fractures continues to pose challenges even in this age of advancing orthopedics. These fractures have the propensity to go for malunion with cosmetic deformity. This study was done to evaluate the functional results of surgical management of supracondylar fractures of the humerus in children using closed reduction and percutaneous bi-columnar pinning technique.

Methods: 100 patients with Gartlands type II, III and IV supracondylar humerus fractures were operated with closed reduction and pinning using K-wires. Patients were followed up at six weeks, twelve weeks and six months and final evaluation were done using the Mayo elbow performance score (MEPS).

Results: In our study, there were 70 males and 30 female patients with mean age of 6.5 years. 85 cases were had fall on outstretched hand as mode of injury and rest following motor vehicle accident. Gartland type II fractures accounted for 10 cases; type III fractures accounts 88 cases and type IV was only 2 cases. Excellent to good results were seen in 80 cases as per the MEPS at 6 months follow-up.

Conclusions: From our study, we could conclude that closed reduction and bi- column percutaneous pinning offers a reliable fixation which permits early mobilization and good functional outcome in displaced fractures. Increasing the number of wire will allow early mobilization and prevent stiffness. 
Bilateral sequential atypical femur fractures in a patient on zoledronic acid therapy: a case report and review of literature
Authors: Kantanavar Radhakrishna , Desai Mohan Madhav , Shah Kunal Ajitkumar , Shah Swapneel Sunil
Published: October 2019

Bisphosphonates are mainstay of anti-resorptive therapies for osteoporosis. They prevent osteoporotic fractures by 40 to 70 % in women and men with osteoporosis. Use of these medications is not free from complications. A case of 62 year old female who presented with left thigh pain after trivial fall at home. X-ray diagnosed as atypical femur fracture of left femur which was fixed internally with interlock nailing. On 1st postoperative day, she complained of pain in right thigh. X-ray revealed an atypical femur fracture of left femur shaft which was also fixed internally with nailing. Biochemical investigations were suggestive of effectiveness of zoledronic therapy. We report this first case of bilateral sequential atypical femur fractures that was treated with zoledronate for 2 years. To our knowledge there are reports of oral alendronate therapy with atypical femoral fractures but none on zoledronic acid.

 
Kliniczne metody wspomagania niewydolnej wątroby
Authors: Ciężkowska Małgorzata , Pluta Krzysztof
Published: October 2019

Liver diseases that lead to its failure are one of the most frequent causes of death worldwide. Taking into account liverâs complexity, there are no drug for acute or acute on chronic liver failure treatment. So far the only effective therapy is the liver transplantation. Unfortunately donor shortage is a main problem of this therapy. Due to this fact scientists have been looking for a new alternatives. The most promising are cell transplantation and bioartificial support systems. Without doubt hepatocytes are the best source of cells to use. But isolated human hepatocytes dedifferentiate very quickly and lose their functions ex vivo. Therefore, the new sources of cells, which could replace hepatocytes, are highly sought after. It is believed that, in order to help patients suffering from liver disease, the approach to solve this problem should be considered on different levels.
Na dobre i na złe: rola endogennych retroelementów u człowieka
Authors: Zawadzka Małgorzata , Pachulska-Wieczorek Katarzyna
Published: October 2019

Transposable elements (TEs) are the sequences that are able to „jump” across the genome. They are found in virtually all organisms including human. Although in human, the majority of TEs lost their ability to autonomous transposition, they make up almost half of our genome, and played important roles in genome evolution. Fast progress in deep sequencing and functional analysis has revealed the importance of domesÂ­ticated copies of transposable elements, including their regulatory sequences, transcripts and proteins in normal cells functioning. However, a growing numer of evidence suggest the involvment of TEs in development and progression of autoimmune and neurodegenerative disaeses as well as in many types of cancer. In this review we summarize the current state of knowledge about the LTR retroelements: endogenous retroviruses (ERVs) and Ty3/Gypsy retrotransposons, and their role in human organism.
The Implementation of Parate Executie of Mortgage under Plateau Price in an Effort of Solving Bad Loan (Analysis on Verdict of Supreme Court of the Republic of Indonesia Number: 471 K/Pdt/2015)
Authors: Ikhsan Ikhwan , Azheri Busyra , Rembrandt Rembrandt
Published: October 2019

The objectives of this present research are: 1) to know and to analyze legal consideration done by judges towards limit value under plateau price from auction object in the implementation of Mortgage Parate Executie as the Effort to Solve Bad Loan; 2) to achieve legal certainty in determining limit value in the implementation of Mortgage Parate Executie in order to achieve legal justice in the community. In this research, the writers conduct judicial normative; this research is descriptive-analytical; data obtained are based on secondary data by doing library research and document study. From this research result, it is known that: 1) judges’ verdict in case of the implementation of mortgage parate executie is determined by the approach used by the judges to adjudicate. In the case study researched, the judge tends to consider good attention from the auction holder. Therefore, if the technical regulation regarding to auction, the judge assumes that the auction has been done legally although the determination of limit value by the auction appellant is not reliable from scientific method side in determining it; 2) the effort that can be done in order that the implementation of mortgage parate executie can run well is by doing revision of implementation regulation from technical guidelines of auction. It is in order that State Assets and Auction Service Office can be given authorities to conduct correction towards limit value determination of mortgage object determined by the auction appellant.
Verification of Acquisition Duty of Right on Land and Building by Office for Management of Finance and Regional Revenue towards Conveyance of Rights in Pariaman
Authors: Aurora Ulthri , Yuslim Yuslim , Khairani Khairani
Published: October 2019

The objectives of this research are: 1) to know How the Verification of Acquisition Duty of Right on Land and Building Made by Land Deed Official is;   2) to know How the Verification of Acquisition Duty of Right on Land and Building by Office for Management of Finance and Regional Revenue towards inheritance is; 3) to know How Legal Consequence of Verification of Acquisition Duty of Right on Land and Building by Office for Management of Finance and Regional Revenue towards trade contract. The approach method used in this thesis is a judicial-sociological or empirical approach method, known also as socio-legal research. Verification of Acquisition Duty of Right on Land and Building Determination on Trade by Office for Management of Finance and Regional Revenue of Pariaman is based on market value that should be based on transaction value as in line with Regional Regulation on Verification of Acquisition Duty of Right on Land and Building of Pariaman and it also does not fulfill the legal requirement of agreement and the principle of contracting freedom. Verification of Acquisition Duty of Right on Land and Building on Inheritance done by Office for Management of Finance and Regional Revenue in Pariaman is based on market value which is in accordance with the Regional Regulation of Acquisition Duty of Right on Land and Building of Pariaman, its processes is similar to Acquisition Duty of Right on Land and Building on Trade which are field survey and by seeing the conveyance of rights previously. The legal consequence of verification of Acquisition Duty of Right on Land and Building determination by Office for Management of Finance and Regional Revenue towards Land Deed Official specifically trade contract which is null and void because it violates the principle of contracting freedom and the legal requirement of contract.
MANAGEMENT ACTIVITIES EFFECTIVENESS IN MODERN RUSSIAN INSTITUTION IN THE CONTEXT OF HEAD WORKPLACE MODELING
Authors: K. Semenova Elmira , G. Volkov Yuriy , V. Uzunov Vladimir , V. Popov Alexander , V. Vereshchagina Anna
Published: October 2019

Purpose: The scientific approach to the organization of labor and the workplace of the institution head involves the search for the most optimal model or technique acceptable to the Russian conditions within the current management culture, traditional views on the nature of managerial work, the scale and effectiveness of management activities.

Methodology: Methodological guidelines for the study of workplaces’ organization of credit and financial institutions’ heads are based on the provisions of modern ergonomics and the principles of a system-based approach, allowing justifying as a significant one the environment-oriented approach.

Result: The obtained results served as the basis for the development of appropriate recommendations to optimize the current situation in the context of eliminating existing gaps and problems in the credit and financial sector of the Russian economy from the standpoint of optimizing the process of organizing working places for managers of institutions in this profile.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of the Management Activities Effectiveness in Modern Russian Institution in the context of Head Workplace Modeling is presented in a comprehensive and complete manner.
Psikiyatri Polikliniğine Başvuran 18-65 Yaş Arası Evli Hastalarda Cinsel İşlev Bozukluğu Sıklığı ve Sosyodemografik Veriler ile İlişkisi
Authors: GÜNAYDIN Dilek , TİRYAKİ Ahmet , SAĞLAM AYKUT Demet , CİVİL ARSLAN Filiz
Published: October 2019

Amaç: Bu çalışmada psikiyatri polikliniğine ayaktan başvuran
hastalarda cinsel işlev bozukluğu (CİB) sıklığı ve CİB ile sosyodemografik
veriler arasındaki ilişkinin araştırılması amaçlanmıştır.Yöntem: Çalışmaya tarama sorularını içeren formu doldurmayı kabul
eden 369 kadın ve 232 erkek hasta alınmıştır. Olası bir CİB olduğu düşünülen
275 kadın ve 145 erkek hastadan görüşmeyi kabul eden 172 kadın ve 83 erkek
hasta ile görüşülmüştür. DSM-V tanı kriterlerine göre klinik görüşme ile CİB
tanısı konulmuştur.Bulgular: CİB sıklığı kadınlarda %67.4, erkeklerde %53 oranında
tespit edilmiştir. Kadınlarda sosyodemografik verilerden 38 yaş üzerinde olanlarda, çocuk sayısı üç ve üzerinde olanlarda,
evlilik süresi 15 yıl ve üzerinde olanlarda CİB anlamlı olarak daha yüksek
saptanmıştır (sırasıyla; p=0.034, p=0.007, p=0.015). Erkeklerde ise
sosyodemografik veriler ile CİB arasında
istatistiksel olarak anlamlı bir ilişki saptanmamıştır.

Sonuç: Çalışmamızda CİB’in psikiyatri polikliniğine başvuran kadın
ve erkek hastalarda oldukça sık görüldüğü tespit edilmiştir. Ek olarak CİB’in kadınlarda
sosyodemografik verilerden yaş, çocuk sayısı, evlilik süresi ile ilişkili
olduğu tespit edilmişken, erkeklerde ise sosyodemografik verilerle ilişkisi
tespit edilmemiştir.
Çorum Bölgesinde Yaşayan İnflamatuar Romatizmal Hastalıkları Olan Kişilerde Tanı ve Tedavi Gecikmesinin Değerlendirilmesi
Authors: ÖZTEKİN Coşkun , DOĞAN İsmail , ÖZKARA Adem , ÖZBOLAT Fulya , YILMAZEL Gülay
Published: October 2019

Amaç: Bu çalışma ile Çorum bölgesinde yaşayan inflamatuar romatizmal hastalıkları olan kişilerde tanı ve tedavi gecikmesinin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Tanımlayıcı özellikteki bu çalışma Eylül-Kasım 2018 tarihleri arasında Çorum ilinde yapıldı. Araştırmaya 119 hasta dahil edildi. Araştırmada verilerin analizi SPSS 22.0 paket programı ile gerçekleştirildi. Verilerin değerlendirilmesinde yüzdelik, ortalama, Ki-kare (Chi-square) testi kullanıldı. Değerlendirmelerde p<0.05 değeri anlamlı kabul edildi.Bulgular: Araştırma grubunun yaş ortalaması 46,00±14,00 yıl olup katılımcıların %63,0’ü kadın ve %86,7’si lise ve daha az eğitime sahipti. Katılımcıların üçte birinden fazlası romatoid artrit tanısı almıştı. Herhangi bir inflamatuar romatizmal hastalık tanısını ilk olarak romatolog tarafından alan bireylerin oranı %50,4 iken aile hekimleri tarafından ilk tanıyı alanların oranı %2,5’dir. Katılımcıların %49,6’sında tanıda gecikme olduğu belirlendi. Katılımcılar tarafından tedaviye başlamada gecikmenin en önemli nedeni olarak %63,6 ile doktor gösterildi. Katılımcıların sosyo-demografik özelliklerinin tedaviye başlamada gecikmenin üzerinde etkisinin olmadığı belirlendi (p<0.05).Sonuç: Çalışmamızda inflamatuar hastalıklarda tanı gecikmesinin sosyo-demografik özelliklerden etkilenmeksizin yüksek olduğu saptanmıştır. Geriatrik dönem nüfusunun giderek arttığı ülkemizde mezuniyet öncesi ve sonrası romatolojik hastalıkla ilgili eğitim programlarının artırılması, hastaların tanı, tedavileri ve komplikasyonlardan korunmaları kapsamında faydalar sağlayabilir.
Could Value-Based Purchasing Approach Be Used in Assessment of Healthcare Delivery Outputs?
Authors: SİMSİR İsmail , ALTINDİŞ Selma
Published: October 2019

ABSTRACTIn spite of increasing expenditures for health services, the lack of improvement in the quality and patient safety at the desired level brought about the search for reform of the reimbursement mechanisms. The main purpose of the present review is a search for a comprehensive answer for the question of “Can Value-based Purchasing (VPB) approach emerged as such kind of quest and applications developed in this context be used to evaluate the outputs of health service delivery?”. According to the studies, the VBP approach and especially Hospital Value-based Purchasing Program and Hospital-Acquired Conditions Program which are the two applications developed under this approach can provide effective results in evaluating the outputs in health services and improving quality and patient safety. The data show that the VBP approach in health care has the potential to contribute significantly to improving the quality and patient safety level of the health care service and to keep costs under control. In this context, Hospital Value-based Purchasing and Hospital-Acquired Conditions Programs draw attention in terms of its potential to be implemented especially in the public sphere in our country. The realization of the research and applications in our country aimed at revealing the potential benefits of the mentioned programs will facilitate the evaluation.
A UTILIZAÇÃO DOS PROCESSOS PEDAGÓGICOS DE GEOGRAFIA NO ENSINO FUNDAMENTAL (1º AO 5º ANO) DE DUAS ESCOLAS DA REDE MUNICIPAL DE CRICIÚMA/SC
Authors: Zanette Celina Maria Moretti , Marcelino Andréa Rabelo
Published: October 2019

A disciplina de Geografia possui características essenciais praticadas no Ensino Fundamental de primeiro ao quinto ano, estudando o funcionamento da natureza, a relação entre o processo histórico que regula a formação das sociedades humanas, através da observação do espaço geográfico e da paisagem. Buscou-se neste artigo, analisar a utilização dos processos pedagógicos do ensino de geografia, utilizadas em duas escolas de ensino fundamental (1º ao 5ª ano) da rede pública do município de Criciúma/SC. A fim de investigar os processos pedagógicos de Geografia, foi realizada uma pesquisa de campo de abordagem qualitativa, utilizando-se de questionamentos previamente estabelecidos, para aproximar-se das possíveis respostas em relação ao problema apresentado. Os dados coletados foram analisados à luz teórica dos seguintes autores: Brabant (2006), Brasil (1997-1998-2017), Callai (2013), Castrogiovanni (1998 – 2010), Cavalcanti (2010), Fernandes (2008), Freire (1996), Gil (1997), Minayo (2007), Passine (2007) Pereira (2011) e Schäffer (2003). Através da pesquisa realizada, foi possível perceber como as professoras ainda desconhecem os diferentes processos pedagógicos,para enriquecerem suas aulas através de experimentos, desafiando seus alunos, despertando a curiosidade e investigação, de forma a aprimorar a qualidade do ensino nesta área do conhecimento.PALAVRAS-CHAVE: Geografia. Ensino Fundamental. Processos Pedagógicos.
O ESTÁGIO OBRIGATÓRIO NA FORMAÇÃO INICIAL DO (A) PEDAGOGO (A) EM UM CURSO A DISTÂNCIA
Authors: Canonica Diane Estevam Cecconi , Bittencourt Ricardo Luiz de
Published: October 2019

O estágio obrigatório é um componente curricular indispensável para a formação inicial do docente, em que proporciona ao acadêmico uma aproximação à prática, e fundamenta-se ao princípio teórico. Enquanto conceito, o estágio, como um processo formativo, promove a investigação e a reflexão sobre a realidade socioeducacional. Buscou-se, neste artigo, investigar como se organiza o estágio obrigatório em um curso a distância. Os principais autores que embasaram esta pesquisa foram Brasil (2006, 2015), Pimenta (2002),Ghedin, Almeida e Leite (2008), Buriolla (2001), Pimenta e Lima (2012), Malanchen (2015), Barreto (2003) e Beloni (1999).O procedimento utilizado para a coleta de dados foi a análise documental, que é respaldada por informações e dados extraídos de documentos. A investigação para este artigo sucedeu-se pela leitura da Grade Curricular e do caderno de estudos de um curso na modalidade a distância. Para uma melhor compreensão desses materiais utilizou-se como instrumento um roteiro de leitura. Ao finalizar este estudo foi possível averiguar que a concepção do estágio obrigatório como prática em um curso a distância, ainda, prevalece o curso superior. Pois, o burocrático transparece como maior intensidade sobre a função do estágio obrigatório para a formação acadêmica e profissional. Entretanto, o estágio deve tomar por base e como príncipio formativo a pesquisa, em que o conhecimento torna-se parte essencial para uma prática transformadora e reflexiva.Palavras-chave: Formação de Professores. Estágio Obrigatório. Ensino a Distância.
MULHERES NEGRAS EDUCADORAS NA REDE MUNICIPAL DE ENSINO DE CRICIÚMA: OS DESAFIOS PARA O ENFRENTAMENTO DO RACISMO E SEXISMO
Authors: Ghisleri Gabriela de Abreu , Ostetto Lucy Cristina
Published: October 2019

A presente pesquisa objetiva refletir sobre narrativas de mulheres negras educadoras na Rede Municipal de Ensino de Criciúma identificando nas suas trajetórias os desafios enfrentados para inserção e permanência no campo educacional, bem como o enfrentamento na luta contra o racismo e o sexismo. Por meio de entrevista com quatro educadoras negras da Rede Municipal de Ensino de Criciúma, foi realizada uma análise qualitativa de natureza básica com o objetivo de compreender suas experiências na educação básica. Para tanto, dialogamos com Bispo (2012), Carneiro (2003), Crenshaw (2012), Jesus (2010), Brasil (2003) e da Lei nº 10.639\03, dispositivo legal regulador das Diretrizes Curriculares Nacionais para a Educação das Relações Étnico-Raciais e para o Ensino de História e Cultura Afro-Brasileira e Africana para a Educação Étnico-racial. Além da discussão a respeito do conteúdo legal, foram abordadas durante a análise questões referentes ao movimento feminista negro, às discriminações raciais sofridas pelas entrevistadas e as dificuldades para ingresso como docentes no campo educacional influenciada por estereótipos impostos pela sociedade brasileira sobre os negros. As educadoras entrevistadas acreditam que a educação é uma ferramenta de transformação capaz de construir uma sociedade mais justa e igualitária sem espaço para o racismo, o preconceito e a discriminação. Apontam que a trajetória para busca destes ideais fortalece uma luta social cujo resultado almejado faz com que qualquer desafio valha à pena.PALAVRAS CHAVE: Educação. Escola. Feminismo negro. Mulheres negras. Narrativas.
DEMANDAS DOS BEBÊS: AS PERCEPÇÕES DAS PROFESSORAS SOBRE O PLANEJAMENTO NO BERÇÁRIO
Authors: Cardoso Kelly de Oliveira , Camargo Gislene
Published: October 2019

O presente artigo teve como objetivo geral analisar as intencionalidades pedagógicas nas turmas de berçário, procurando responder o problema: Como deve acontecer o planejamento no berçário. Com isso, definiram-se como objetivos específicos: compreender a relação cuidar e educar nas turmas de berçário da Educação Infantil, relacionar o cuidar e educar ao planejamento e verificar a importância do projeto como planejamento no berçário. Para responder o problema e atingir os objetivos realizou-se uma pesquisa de campo de abordagem qualitativa. Com relação aos sujeitos da pesquisa, seis professoras da Educação Infantil foram entrevistadas. Dessas quatro já aturam nas turmas de berçário e duas estão atuando; três professoras pertencem a uma escola particular e três professoras a um Centro de Educação Infantil público, ambos localizam-se no município de Sombrio-SC. Como instrumento de coleta de dados utilizou-se entrevista semiestruturada contendo sete perguntas relacionadas ao cuidar e educar, planejamento e rotinas, os dados foram analisados à luz teórica, utilizando os seguintes autores: Brasil (2010), Barbosa e Horn (2008), Freitas (1999), Kramer (2005), entre outros. Neste estudo, foi possível perceber que as professoras apresentam entendimento sobre a importância do planejamento para o berçário, e as entrevistadas utilizam projetos como metodologia, procurando aliar o cuidar e o educar. Em determinados momentos o cuidar ainda se destacou, especialmente no que se refere ao cumprimento das rotinas.PALAVRAS-CHAVE: Cuidar e educar. Planejamento. Rotina. Educação Infantil.