bluuebunny/crossref_metadata_2025 huggingface dataset:
Measuring the Quality of Life Patients with Type 2 Diabetes Mellitus at The North Pontianak Public Health Center and Kitamura Pontianak Clinic Using the Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) and Diabetes Distress Scale 17 (DDS 17)
Authors:   Department of Pharmacy, Medical Faculty, University of Tanjungpura Pontianak, Indonesia, Yuswar Muhammad Akib , Rizkifani Shoma ,   Department of Pharmacy, Medical Faculty, University of Tanjungpura Pontianak, Indonesia
Published: April 2023

Diabetes Mellitus (DM) is a metabolic disease characterized by hyperglycemia. Patients with diabetes mellitus tend to experience distress related to their health problems, as well as self-acceptance of the disease and the various medical actions that must be taken. The stress felt by DM patients will affect the patient's quality of life. Poor quality of life can make metabolic disorders worse, either directly through hormonal stress or indirectly through complications that can arise. This study aims to analyze differences in quality of life and stress levels of patients type 2 DM patients at the North Pontianak Public Health Center and Pontianak Kitamura Clinic. This research used observational method with a cross sectional design. This research is prospective using the Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) and Diabetes Distress Scale 17 (DDS 17). The population in this study were all type 2 DM patients undergoing treatment at the North Pontianak Public Health Center and Kitamura Clinic. Data collection was carried out by accidental sampling and a sample of 150 patients was obtained, consisting of 100 Public Health Center’s patients and 50 Clinic’s patients. The results showed that the quality of life of type 2 DM patients at the Public Health Center was higher than the patients at the Kitamura Clinic and there was a significant difference between the quality of life of type 2 DM patients at the Public Health Center and Clinics with a sig value of 0.013 (p<0.05). The stress indicator on the emotional burden of patients at the Clinic was higher compared to the patients at Public Health Center, but there was no significant difference between the stress levels of type 2 DM patients at the Public Health Center and the Kitamura Clinic with a sig value of 0.196 (p>0.05).
Vitamin C Administration in Breast Cancer After Surgery Treatment : A Review
Authors:   General Practicioner, Suradadi Regional Public Hospital, Tegal, Indonesia, Kurniawan Rio Aditya
Published: April 2023

Introduction : Breast cancer is still the most common type of cancer, and surgery is still an alternative available. Postoperative care for breast cancer is an action that must be evaluated from a variety of perspectives. Methods : The information retrieval feature of the PubMed and Cambridge Core literature search engines was used to find review of literature articles for this journal. The periodicals on which the literature was predicated were obtained. Result Vitamin C has various functions in cases of breast cancer. A special review in this paper is in terms of wound healing and anti-pain modulation in postoperative breast cancer. The existence of this is considered significant and can be used as postoperative therapy. Conclusion : Vitamin C involvement in postoperative therapy for breast cancer is expected to have benefits in terms of wound healing as well as modulation of anti-pain interventions. Furthermore, vitamin C therapy is not permitted as an adjunctive treatment or to lower the risk of breast cancer or to inhibit post-surgical complications within those cases.
A INTRÍNSECA RELAÇÃO DA MICROBIOTA INTESTINAL COM A SAÚDE MENTAL
Authors: Moura Marcela Mamede de Araújo , Mendonça Marcos Antônio , Novaes Mayra Rozalia Loureiro , Sousa Marianna Ramalho de , Santos Marcella Simão dos
Published: April 2023

O eixo intestino-cérebro é definido com uma comunicação entre o sistema nervoso central (SNC) e o ambiente entérico do intestino. A microbiota humana além de interferir na saúde intestinal, também têm um papel importante no SNC e pode influenciar em distúrbios como depressão e ansiedade. O estudo objetivou analisar a relação entre a microbiota e a saúde mental. Foi realizada uma busca nas plataformas PubMed e DOAJ através dos descritores: “gut-brain axis”, “depression”, “anxiety”, “microbiota”, “stress”. Um total de 25 artigos foram incluídos após a aplicação de critérios de inclusão: artigos originais com delineamento experimental ou observacional no período de 2011 a 2021; idioma inglês ou português. Foram descartados artigos que não trabalhavam a interação da microbiota com os transtornos mentais e artigos duplicados. Foi observado que o eixo intestino-cérebro representa uma ligação importante entre a saúde intestinal e o bem-estar psicológico e que a disbiose pode interferir na saúde mental e física do indivíduo. Em conclusão, pôde-se perceber uma relação importante entre a microbiota intestinal e a fisiopatologia dessas doenças e que a ingestão de probióticos tem grande potencial no tratamento.
IMPACT OF TEACHER-STUDENT FAVORITISM ON STUDENTS’ LEARNING OUTCOMES AT UNIVERSITY LEVEL
Authors: Zaki Khizer Ahmed , Rafiq Shahid , Afzal Ayesha
Published: April 2023

This study aimed to explore teacher favoritism's impact on students' learning outcomes at university level. Favoritism is a common trend in classrooms as teachers give special treatment to a few students despite not providing their best work, instead because of other reasons, like the personal preferences and liking/disliking. This research focuses on how students think about teacher-student favoritism and how it impacts students' learning outcomes. To answer these questions positivism paradigm was adhered to. The research followed a quantitative approach, and the survey method was considered best suited for this study. Population of this study consisted of all public sector universities of Lahore. The sample was collected from five general category public sector universities of Lahore. The descriptive and inferential statistics were used to conclude. Therefore, it was found that favoritism significantly impacts student learning outcomes at the university level. It causes insecurity, dissatisfaction, conflicts, and revengeful emotions among students, that directly affect their learning of students. Favoritism also causes less self-confidence in students. Favoritism impacts classroom environment, which is directly related to lousy learning outcomes.
Strategi Guru dalam Mengatasi Problematika pada Proses Pembelajaran PAI Kurikulum 2013 di SMP Cerdas Murni Tembung
Authors: Hasibuan Raudhatul Ma'wa , Neliwati Neliwati , Nuraisyah Nuraisyah , Aulaz Ibnu
Published: April 2023

Di SMP Cerdas Murni Tembung, tujuan penelitian ini adalah untuk mengetahui Pendekatan Guru dalam Mengatasi Kendala Proses Pembelajaran pada Kurikulum 2013 PAI. Menggunakan penelitian kualitatif deskripsi dalam penelitian ini. Wawancara, observasi, dan dokumentasi adalah metode yang digunakan. Reduksi data, penyajian data, dan penarikan kesimpulan data merupakan teknik analisis data penelitian. Selain itu, ekstensi, ketekunan, dan triangulasi pengamatan dalam penelitian ini memastikan validitas data. Temuan penelitian ini menunjukkan: Guru PAI di SMP Cerdas Murni Tembung menghadapi sejumlah tantangan selama proses pembelajaran, antara lain (1) menentukan strategi dan metode pembelajaran yang tepat. 2) Siswa kurang fokus dalam belajar dan manajemen waktu. 3) Penggunaan perangkat elektronik secara berlebihan.
Implementasi Metode Wafa dengan Pemberian Reward dalam Meningkatkan Motivasi Menghafal Al-Qur’an Siswa di SMP Mujahidin Surabaya
Authors: Muzaiyanah Indri Ayu , Hayumuti Hayumuti , Asrori Asrori
Published: April 2023

Untuk menjadikan seorang siswa/siswi ber akhlakul karimah kita harus menanamkan di dalam diri mereka Al-Qur’an adalah sebagai pedoman hidup, menghafal Al-Qur’an menjadi salah satu kita untuk mendapatkan hadiah yang terbaik dari Allah di surga kelak, untuk menghafal Al-Qur’an diharapkan untuk bisa dan terbiasa dengan ayat-ayat Al-Qur’an dan tidak merasakan bosan agar bisa menjadi seorang penghafal, untuk metode penelitian kali ini berfokus kepada penelitian kualitatif dengan observasi lapangan, dalam sekolah SMP Mujahidin Surabaya murid harus menghafal minimal 2 atau 3 juz untuk syarat kelulusan, di sana juga jika sudah mencapai target maka akan mendapatkan sebuah reward yang akan disampaikan ke orangtua murid, metode wafa adalah satu satunya metode yang mereka gunakan untuk menggerakkan siswa agar bisa menghafal menggunakan stimulasi otak kanannya. Selain menggunakan metode pembelajaran yang mengasyikkan SMP Mujahidin Surabaya menyajikan reward untuk anak didiknya yang bisa mencapai target hafalan.
Implementasi Model ATIK untuk Meningkatkan Keterampilan Proses Sains di TK Islam Baitushshobirin Kecamatan Tanjung Priok
Authors: Solikhah Solikhah , Ismiati Ismiati , Maulida Ida , Watini Sri
Published: April 2023

Usia Emas disebut juga sebagai masa kanak-kanak awal.  Istilah Anak Usia Dini juga dapat di gunakan untuk merujuk pada anak-anak antara Usia 0 - 8 tahun yang berada pada tahap perkembangan yang rentan dan sedang mengalami pertumbuhan yang cepat dan penting untuk kehidupan masa depan mereka. Salah satu aspek ketrampilan yang perlu di kembangkan adalah ketrampilan proses Sains. Oleh karena itu perlu adanya penggunaan model yang tepat sehingga ketrampilan proses Sains pada anak tercapai secara optimal. Penelitian ini bertujuan untuk mengetahui sejauh mana peningkatan Ketrampilan proses Sains dengan menggunakan model pembelajaran ATIK. Metode yang di gunakan dalam penelitian ini adalah metode Kualitatif dengan pendekatan diskriptif. Teknik pengumpulan data dengan menggunakan cara Observasi, Wawancara dan dokumen foto yang mendukung. Analisis data menggunakan analisis Diskriptif Kualitatif dengan model Miles dan Huberman. Penggunaan Model ATIK terbukti dapat Meningkatkan Ketrampilan Proses Sains di TK Islam Baitushshobirin.
Peran Orang Tua dalam Perkembangan Agama dan Moral pada Anak Usia Dini
Authors: Uswatun Uswatun , Rohayati Rohayati
Published: April 2023

Pendidikan anak usia dini (PAUD) adalah jenjang pendidikan sebelum pendidikan dasar merupakan suatu upaya pembinaan yang ditujukan bagi anak sejak lahir sampai dengan usia 6 tahun. Tujuan dari penelitian ini adalah untuk mengetahuai peran orang tua dalam perkembangan agama dan moral pada anak usia dini. Penelitian ini adalah penelitian studi literatur menggunakan metode kualitatif, pengumpulan datanya menggunakan sumber referensi ditelusuri dari buku maupun artikel yang telah di terbitkan. peran orang tua dalam perkembangan agama dan moral pada anak usia dini dilakukan melalui simulasi atau rangsangan pendidikan untuk membantu pertumbuhan dan perkembangan jasmani dan rohani agar memiliki kesiapan dalam memasuki pendidikan lebih lanjut, yang diselenggarakan pada jalur formal, informal, dan non formal. Keluarga merupakan pendidikan pertama untuk anak. Karena keluarga bagi anak adalah dasar yang utama dalam menanamkan nilai agama untuk anak. Orang tua adalah yang pertama kali dikenal oleh anak dari sejak lahir, tumbuh dan berkembang hingga anak mengenal orang lain.
The Use of The Round-Robin Technique on Students’ Vocabulary Mastery for The Second Graders of SMK Al Maksum Langkat
Authors: Malau Khairunnisa Br. , Rahmadhani Maitri , Suprayetno Edi
Published: April 2023

The objective of this research was to determine whether the Round Robin technique significantly affects students’ vocabulary mastery for the second graders of SMK AL Maksum Langkat. A quasi-experimental research design was used in this study. There were 51 students taken as sample by using purposive sampling technique from 116 populations of second graders of SMK AL Maksum Langkat. There were 28 students from class XI OTKP as a control class, and 23 students from class XI as an experimental class. There were six meetings conducted by the researcher which consisted of one meeting for pre-test, four meetings for treatments, and one meeting for the post-test. The Round Robin technique was applied to the experimental class and the conventional technique was applied in the control class. From the analysis of the data by using Independent Sample T-test in SPSS 25.00 it was found that the data were in normal distribution and had the same variance or homogenous. The result of the hypothesis test showed that the students’ mean score of pre-test was lower than the post-test (79,30 > 53,11) and the Sig. (p value) < ? = 0.05 (0,000 < 0,05), it can be said that H0 was rejected and Ha was accepted.  it can be concluded that there was a significant effect of using the Round Robin technique on students’ vocabulary mastery in the second graders of SMK AL Maksum Langkat.
Pengembangan Potensi Buah Mangga Gedong Gincu Majalengka ke Pasar Internasional
Authors: Sukandi Pipin , Landy A
Published: April 2023

Permintaan terhadap buah mangga jenis gedong gincu di pasar nasional maupun international terus meningkat. Namun peningkatan tersebut harus diiringi dengan pemasaran yang baik dan terstruktur. Mangga gedong gincu merupakan varietas mangga spesifik lokasi Provinsi Jawa Barat yang bernilai ekonomi tinggi dan mempunyai prospek sebagai komoditas buah unggulan ekspor Indonesia. Penelitian ini dilakukan di Desa Cijurey Kecamatan Panyingkiran Kabupaten Majalengka yang bertujuan mengetahui strategi yang harus diterapkan dalam menangani masalah yang ada pada pengembangan usaha mangga gedong gincu di Majalengka. Hasil kajian menunjukkan bahwa pada umumnya, pemasaran mangga gedong gincu masih konvensional dan bergantung pada pedagang pengepul (tengkulak). Hal ini menyebabkan potensi ekspor yang terbuka lebar belum dapat dimanfaatkan dengan baik. Untuk meningkatkan produksi dan pemasaran mangga gedong gincu diperlukan upaya perbaikan dari tingkat on farm sampai off farm. Upaya peningkatan daya saing pada tataran on farm dapat dilakukan melalui perbaikan dalam produksi, produktivitas, dan kualitas buah.
Respon bibit kelapa sawit terhadap aplikasi urea berlapis zeolit sebagai pupuk slow release nitrogen
Authors: Kautsar Valensi , Hangger Gahara Mawandha , Aldymas Bimantara
Published: April 2023

Nitrogen merupakan unsur hara esensial, oleh karenanya ketersediaan nitrogen anorganik sangat penting dalam mendukung perkembangan bibit kelapa sawit. Adanya sifat urea yang lepas cepat, menyebabkan urea mudah hilang sebelum diserap oleh tanaman. Berbagai upaya telah dilakukan untuk mengubah sifat urea dari lepas cepat menjadi lepas lambat. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas pelapisan urea dengan zeolit dengan metode yang mudah. Urea dengan lapisan zeolit dibandingkan dengan urea tanpa lapisan zeolit  selama tiga bulan aplikasi pemupukan bibit sawit main nursery. Penelitian ini menggunakan dua jenis zeolit yaitu zeolit non aktivasi dan zeolit aktivasi, dengan dua persentase yaitu 20% dan 40%. Adanya pelapisan zeolit menyebabkan penurunan higroskopisitas urea dan kelarutan urea pada larutan aquades. Selain itu pelapisan urea pada berbagai persentase dan berbagai tipe zeolit mampu menghasilkan pertumbuhan yang sama baiknya dengan pupuk urea tanpa zeolit. Hal ini menunjukkan bahwa baik zeolit yang diaktivasi maupun non aktivasi dapat dimanfaatkan dalam pelapisan urea yang berdampak pada penurunan jumlah dosis urea yang digunakan dalam pembibitan.
Research on “Practice Market” Oriented Art Education Teaching System--Visual Communication Design as an Example
Authors: Gao Xiang
Published: April 2023

With the rapid development of the market economy, higher education institutions are facing new challenges in meeting the demands for innovative and entrepreneurial abilities of higher art talents. This paper focuses on visual communication design, which requires not only the basic theoretical quality of art majors but also practical skills to meet social and market needs. Through an analysis of the current situation of visual communication design specialty, this paper identifies existing problems in teaching and proposes measures to optimize and solve these problems. By doing so, this paper aims to better strengthen the training of students majoring in visual communication design. The proposed measures include incorporating industry projects into the curriculum, enhancing practical training, and encouraging interdisciplinary collaborations. It is hoped that these measures will improve the quality of teaching and ultimately produce graduates who possess both theoretical knowledge and practical skills needed for the industry.
Charging Forward: Investigating Consumer Attitudes and Perceptions on Electric Vehicles
Authors: Vithayathil Antony
Published: April 2023

The adoption of electric vehicles (EVs) is a crucial step towards achieving sustainable transportation. However, the success of EVs is heavily dependent on the consumers' perception and acceptance of this technology. This paper presents a systematic review of research articles published on the topic of consumer perception of electric vehicles. The review includes articles published between 2015 and 2021 and encompasses a wide range of perspectives, including consumer attitudes, preferences, and barriers to adoption. The findings suggest that consumers have positive perceptions of EVs in terms of environmental benefits, but also express concerns regarding the range, charging infrastructure, and higher purchase cost. Additionally, several studies have found that socio-demographic factors, such as income, age, and education, play a significant role in shaping consumer perceptions of EVs. This paper provides valuable insights into the current state of research on consumer perception of EVs and highlights areas for future research. The results of this review can be useful for policymakers, manufacturers, and other stakeholders in developing effective strategies to promote the adoption of EVs.
De waardering van de letselschadezitting: een verkenning
Authors: van Eekeren P.J.
Published: April 2023

De waardering van de letselschadezitting: een verkenning.

Op 3 oktober 2022 vond voor de 15e keer het jaarlijkse Gronings letselschadecongres plaats, met als thema ‘de prijs van letselschade’. Traditiegetrouw spreekt daar een rechter als hekkensluiter. Deze keer was het de beurt aan Ellen van Eekeren. Zij nam, eendachtig het thema van dit congres, de deelnemers mee voor een kijkje in de rechterlijke keuken als het gaat om de zitting, en dan in het bijzonder ‘de letselschadezitting’. Zij verkende met hen de diverse factoren die de waarde van de letselschadezitting bepalen.
Juventude, pandemia e ativismo digital
Authors: Neves Laura Bastos Pimenta , dos Santos Isabella Corradi , Brasil Flávia de Paula Duque , Carneiro Ricardo
Published: April 2023

O artigo aborda os problemas emergentes para a juventude no contexto da pandemia de Covid-19 e como têm sido tematizados, tendo como objetivo identificar e analisar sua atuação e repertórios de ação coletiva mobilizados, com ênfase no ativismo digital. Como ponto de partida, realiza-se uma breve revisão sobre movimentos sociais, repertórios de ação coletiva e ativismo digital. A metodologia empregada envolveu levantamentos documentais e de dados secundários, bem como a realização de entrevistas em profundidade com jovens ativistas representantes no Comitê Gestor do Centro de Referência da Juventude de Belo Horizonte e em outras instituições participativas. As principais constatações proporcionadas pela pesquisa referem-se às lacunas e déficits de atuação do Estado em relação às políticas para a juventude, bem como à fraca articulação entre Estado e sociedade civil. As iniciativas da sociedade civil buscam suprir tais lacunas, mobilizando diferentes repertórios de ação, incluindo o ativismo digital.
A Ticklish Parrot-dox: Dual Diagnosis of Lyme Carditis and Psittacosis
Authors: Tran Paul , Maayah Marah , MacLeod Ryan , Frampton Jennifer
Published: April 2023

We present a young female who presented with three weeks of dry cough, dizziness, shortness of breath, headache, and chest pressure. She was found to have atrial flutter, atrial fibrillation and complete heart block, and eventually diagnosed with Lyme carditis. She was also diagnosed with psittacosis based on her high risk exposure to bird feces and her symptoms of dry cough and headache that persisted despite the initiation of treatment for Lyme disease. This case highlights the need for high clinical suspicion and early treatment of Lyme carditis in younger individuals living in endemic areas.
Design and Implementation of a Secure Virtual Private Network Over an Open Network (Internet)
Authors: Forbacha Suh Charles , Agwu Mbuya Josiah Anyam
Published: April 2023

Aim: The main objective of this research project is to design and implement a functional secure virtual private network over the internet considering that use of traditional fixed telephones lines is not cost effective and it is unsecured especially in the context of Cameroon.

Methods: In the VPN, internet is used as the data pipelined replacing the traditional data lines. This approach was deployed through simulation with CISCO Packet Tracer.

Results: Simulation results showed that the system can provide a secured, reliable and cost effective transmission system over the Internet for organizations in Cameroon.  As such, VPNs form an integral part of remote business communications across the internet due to the inherent risks that exist when sending private information over a public network.

Conclusion: VPNs not only prevent unethical use of private business correspondence by unauthorized parties but they also play an important role in reducing the environmental impact of business travel.

Recommendations: This study recommend an organization which considers security as its top priority to embrace the rather expensive solution of implementing an email/Web/DNS/FTP server at each site rather than using only a single email/web/DNS/FTP server for the entire intranet. This will reduce the amount of information that organization sends across the Internet and increase information access speeds. Home users or small office can equally be installed with an email/web/DNS/FTP server. Also, in the remote access case, a company can outsource the installation and management of their remote access VPN server to the ISP. Moreover, just using IPSec for remote access users is not enough. Remote access IPSec VPN implementation should always be associated with a tunneling protocol such as PPTP.
Determinantes do índice de transparência municipal em Portugal (2013 a 2017)
Authors: Martinho Carla Alexandra , Dos Santos Paula Alexandra Rocha Gomes , Escaninha Mariana , Pinho Carlos Pedro dos Santos
Published: April 2023

A transparência assenta na disponibilização de informação sobre a gestão, sendo imprescindível a uma boa governação pública. Dada a divulgação do Índice de Transparência Municipal (ITM) relativo aos anos de 2013 a 2017, a presente investigação tem como objetivo estudar as determinantes que influenciam este índice, naquele período. Para a realização do estudo utilizaram-se dados dos 308 municípios portugueses, sendo o valor do ITM a variável que se pretende explicar. Para a respetiva análise, recorreu-se à análise estatística via modelos de regressão linear múltipla com dados em painel. Como principal conclusão da investigação realizada retira-se que as variáveis despesa efetiva per capita, taxa de população idosa e percentagem de abstenção, demonstraram ser determinantes do índice de transparência municipal para os anos em análise. O presente estudo pretende contribuir para o conhecimento no âmbito da transparência dos governos locais em Portugal.
Effect of Organic and Inorganic Fertilizer on Vegetative Growth Parameter of Lilium (Lilium Longiflorum) cv. Pavia under Shade Net Condition
Authors: Kumar Narendra , Prasad V. M. , Kerketta Anita , Das Kanchan S.
Published: April 2023

The present investigation entitled, “Effect of Organic and Inorganic Fertilizer on Vegetative Growth Parameter of Lilium (Lilium Longiflorum) cv. Pavia Under Shade Net Condition” was under taken in the Department of Horticulture, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, (Allahabad). During winter season of 2020-2021, 2021-2022 and Pooled. The experiment was layout in Randomized Block Design (RBD) with 13 treatments and each treatment replicated thrice. The treatments consist of different combinations of inorganic fertilizers (N, P and K) and organic fertilizers (FYM, Vermicompost and Poultry Manure) and control (No fertilizers and manures). The treatment T5 50% RDF + FYM 14 t ha-1 was found the statistically significant compared to other treatment combination, which recorded highest plant height (23.68, 57.11 and 76.41 cm), spread area (8.19 cm2, 15.54 cm2 and 18.47 cm2), Number of leaves (36.63, 57.11 and 76.41), Leaf area (15.03 cm2, 15.63 cm2 and 15.33 cm2), Chlorophyll content (66.11 mg, 65.60 mg and 65.86  mg), followed by T9 25% RDF + Vermicompost 6.9 t ha-1 and lowest yield was obtained from T0 (control).
Microenvironmental Changes in Mediastinal Fat-associated Lymphoid Clusters and Lungs in Early and Late Stages of Metastatic Lung Cancer Induction
Authors: Elewa Yaser Hosny Ali , Abd Elwakil Mahmoud M , Harashima Hideyoshi , Mohamed Sherif Kh A , Zahran Mahmoud Hosny
Published: April 2023

The prognosis of metastatic lung melanoma (MLM) has been reported to be poor. An increasing number of studies have reported the function of several immune cells in cancer regression. Although the function of mediastinal fat-associated lymphoid clusters (MFALCs) in the progression of inflammatory lung lesions has been previously reported, the association between MLM progression and MFALCs development has remained unexplored. Herein, we compared the microenvironmental changes in the lungs and MFALCs among phosphate-buffered saline (PBS) and cancer groups at early (1 week) and late (2 weeks) stages following the intravenous injection of B16-F10 melanoma cells into C57BL/6 mice. Except for lung CD4+ helper T-cells and Iba1+ macrophage populations of early stage, we observed a significant increase in the proliferating and immune cell (CD20+ B-lymphocytes, CD3+ T-lymphocytes, CD8+ cytotoxic T-cells, CD16+ natural killer (NK) cells populations, area of high endothelial venules, and lung lymphatic vessels in cancer groups at both the stages as compared with the PBS groups. Furthermore, a significant positive correlation was observed between immune cell populations in MFALCs and the lungs (B- and T-lymphocytes, and NK cells in both stages). Collectively, our findings suggest a promising cancer therapeutic strategy via targeting immune cells in MFALCs.
Gender, workplace preferences and firm performance: Looking through the glass door
Authors: Chen Jie , Jing Chenxing , Keasey Kevin , Lim Ivan , Xu Bin
Published: April 2023

Using Glassdoor data we show that women are less satisfied at work than men and that female employees care more about work‐life balance. Further analysis shows that this gender difference in workplace preference vanishes at the manager level, suggesting that women who care less about work‐life balance self‐select into career paths that ultimately lead to management positions. Exploring the performance implications, we show that family‐friendly workplaces with smaller gender gaps in work‐life balance satisfaction are associated with better firm performance. Overall, our study implies that policies that aim to narrow the gender satisfaction gap can be socially and economically desirable.
Successful ablation of a right epicardial accessory pathway via the right ventricular diverticulum in a patient with Wolff‐Parkinson‐White syndrome
Authors: Zhang Zhijun , Ma Changsheng , Li Xuewen , Qu Lijuan , Zhao Bingye , Bai Rong
Published: April 2023

Introduction

We describe one rare case of successful ablation of a right epicardial accessory pathway (AP) via the right ventricular diverticulum in a patient with Wolff‐Parkinson‐White syndrome.

Methods

A 42‐year‐old woman was referred to the hospital for a catheter ablation of Wolf‐Parkinson‐White syndrome. The earliest activation was shown to be present in the region of the tricuspid annulus. However, ablation had no effect on the AP.

Results

We decided to do a selected angiography, in which a big diverticulum near the right tricuspid annulus was shown to be present. Ablation in this region successfully repressed the AP without any recurrences within a follow‐up period of 12 months.

Conclusion

The ventricular diverticulum‐mediated AP is a novel variant of pre‐excitation. It can serve as an anatomical substrate of supraventricular tachycardia, and can be ablated endocardially using an irrigation tip catheter within the diverticulum.
Supplementary Methods, Table 1 and Figure 1 from In Vivo Radioimaging of Bradykinin Receptor B1, a Widely Overexpressed Molecule in Human Cancer
Authors: Lin Kuo-Shyan , Pan Jinhe , Amouroux Guillaume , Turashvili Gulisa , Mesak Felix , Hundal-Jabal Navjit , Pourghiasian Maral , Lau Joseph , Jenni Silvia , Aparicio Samuel , Bénard François
Published: April 2023

Supplementary Methods, Table 1 and Figure 1. Supplementary Methods: Peptide synthesis Table 1: detailed biodistribution data. Supplementary Figure 1: Structure of the radiolabeled peptides evaluated in this study: 68Ga-P03083 (top), 68Ga-SH01078 (middle) and 68Ga-P03034 (bottom).
Supplementary Figure S1 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: April 2023

E-Cadherin expression in cell lines (HK-2, A-498, 786-O).
Supplemental Table S1 from Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model
Authors: Sacco Antonio , Roccaro Aldo M. , Ma Dongdong , Shi Jiantao , Mishima Yuji , Moschetta Michele , Chiarini Marco , Munshi Nikhil , Handin Robert I. , Ghobrial Irene M.
Published: April 2023

Quality control of RNA after human exon enrichement.
Supplemental Figure S2 from Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model
Authors: Sacco Antonio , Roccaro Aldo M. , Ma Dongdong , Shi Jiantao , Mishima Yuji , Moschetta Michele , Chiarini Marco , Munshi Nikhil , Handin Robert I. , Ghobrial Irene M.
Published: April 2023

Breast cancer cells colonize the CHT niches.
Supplementary Figure Legends from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: April 2023

Supplemental figure legends
Supplemental Materials and Methods from PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Authors: Hein Ashley L. , Seshacharyulu Parthasarathy , Rachagani Satyanarayana , Sheinin Yuri M. , Ouellette Michel M. , Ponnusamy Moorthy P. , Mumby Marc C. , Batra Surinder K. , Yan Ying
Published: April 2023

Description of additional details of materials and methodologies used in this study
Supplementary Table 1 to 4 from Tissue Factor Induced by Epithelial–Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells
Authors: Bourcy Morgane , Suarez-Carmona Meggy , Lambert Justine , Francart Marie-Emilie , Schroeder Hélène , Delierneux Céline , Skrypek Nicolas , Thompson Erik W. , Jérusalem Guy , Berx Geert , Thiry Marc , Blacher Silvia , Hollier Brett G. , Noël Agnès , Oury Cécile , Polette Myriam , Gilles Christine
Published: April 2023

Supplementary Table 1: list of siRNA used. Supplementary Table 2: list of primers used. Supplementary Table 3: list of antibodies used in different applications. Supplementary Table 4: list of patients and donors information
Supplementary Figure S1 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Prodigiosin targets CRCSC self-renewal in vitro.
Supplementary Figure 5 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Authors: Crottès David , Rapetti-Mauss Raphael , Alcaraz-Perez Francisca , Tichet Mélanie , Gariano Giuseppina , Martial Sonia , Guizouarn Hélène , Pellissier Bernard , Loubat Agnès , Popa Alexandra , Paquet Agnès , Presta Marco , Tartare-Deckert Sophie , Cayuela Maria Luisa , Martin Patrick , Borgese Franck , Soriani Olivier
Published: April 2023

Sig1R promotes hERG- and AKT-dependent FDM-induced cell spreading, VEGF secretion and endothelial transmigration
Supplementary Figure 7 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Fig. S7 LF3 reduces tumor growth without showing toxicity in vivo.
Supplementary Figure 6 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Fig. S6 Influence of LF3 on gene profiling and differentiation of mouse salivary gland CSCs.
Supplementary Figure 2 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Authors: Crottès David , Rapetti-Mauss Raphael , Alcaraz-Perez Francisca , Tichet Mélanie , Gariano Giuseppina , Martial Sonia , Guizouarn Hélène , Pellissier Bernard , Loubat Agnès , Popa Alexandra , Paquet Agnès , Presta Marco , Tartare-Deckert Sophie , Cayuela Maria Luisa , Martin Patrick , Borgese Franck , Soriani Olivier
Published: April 2023

Sig1R is associated to β1 integrin and promotes β1 integrin / hERG association without altering β1 integrin membrane expression
Supplementary Figure 4 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Fig. S4 LF3 doesn't cause apoptosis or cell death.
Supplementary Figure 1 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Fig. S1 Technology and protein production for the primary High Throughput Screen (HTS).
Supplementary Figure S7 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Transcriptional activity and TGFBR2 overexpression in MCF7 and tamoxifen-resistant cells (TAM-R).
Supplementary Figure S5 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

TGFβ and ERα transcriptional activity.
Supplementary Figure S4 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Pharmacological inhibition of TGFβ signaling.
Supplementary Figure S2 from SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling
Authors: Jiang Hong-Lin , Sun He-Fen , Gao Shui-Ping , Li Liang-Dong , Huang Sheng , Hu Xin , Liu Sheng , Wu Jiong , Shao Zhi-Ming , Jin Wei
Published: April 2023

(A) Kaplan-Meier curves showing that patients with stomach adenocarcinoma and an SSBP1 gene alteration have shorter lifespans than those with stomach adenocarcinoma without an SSBP1 gene alteration in the TCGA cohort (P = 0.013; log-rank test). (B) The left panel shows representative images of mouse lungs six weeks after tail vein injection with the indicated cells, and the right panel shows number of mouse lung metastases (*, P < 0.05). (C) Real-time PCR analysis of metastasis-related target genes by TGF-β in control and stable SSBP1-depleted MDA-MB-231 and MDA-MB-468 cells. The data are presented as the mean {plus minus} SD.
Supplementary Figure S1 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Flow chart of SBII2 cohort study design regarding analysis of TGFBR2 and pSMAD2 biomarker.
Supplementary Figure 3 from NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis
Authors: Shoshan Einav , Braeuer Russell R. , Kamiya Takafumi , Mobley Aaron K. , Huang Li , Vasquez Mayra E. , Velazquez-Torres Guermarie , Chakravarti Nitin , Ivan Cristina , Prieto Victor , Villares Gabriel J. , Bar-Eli Menashe
Published: April 2023

Immunohistochemistry of tumor samples after silencing or overexpressing NFAT1 in melanoma cells
Supplementary Figure S4 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Mild inflammation and polyp-like outgrowths in the colon of AOM-pretreated mice which were fed with J47, J47Î"hly or PBS. (A) Colon length of wild-type BALB/c mice fed with E. coli or PBS. (B) Scores of colonic inflammation of the mice. (C) Representative images of H&E-stained colonic sections illustrating inflammatory cell infiltrates in the mucosa and loss of goblet cells or crypts (indicated by black arrows). (D) Microscopic examination of the H&E-stained colon tissues revealed that macroscopically observed polyps were colorectal lymphoid aggregates. ns, not statistically significant.
Supplementary Figure Legends from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Legends of Supplementary Figure S1-S4
Supplementary Tables and Legends from AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models
Authors: Weir Hazel M. , Bradbury Robert H. , Lawson Mandy , Rabow Alfred A. , Buttar David , Callis Rowena J. , Curwen Jon O. , de Almeida Camila , Ballard Peter , Hulse Michael , Donald Craig S. , Feron Lyman J.L. , Karoutchi Galith , MacFaul Philip , Moss Thomas , Norman Richard A. , Pearson Stuart E. , Tonge Michael , Davies Gareth , Walker Graeme E. , Wilson Zena , Rowlinson Rachel , Powell Steve , Sadler Claire , Richmond Graham , Ladd Brendon , Pazolli Ermira , Mazzola Anne Marie , D'Cruz Celina , De Savi Chris
Published: April 2023

Supplementary Table 1 contains crystallographic data collection and refinements statistics for AZD9496 binding to the human estrogen receptor α ligand binding domain, Supplementary Table 2 shows the rate constants for association, dissociation and equilibrium dissociation constant for AZD9496 binding to the human estrogen receptor α ligand binding domain, Supplementary Table 3 displays IC50 values for AZD9496 binding to androgen, glucocorticoid, progesterone and estrogen receptor β ligand binding domains, Supplementary Table 4 displays IC50s values for cell growth inhibition of a panel of estrogen receptor positive and negative cell lines using AZD9496.
Supplementary Table S12 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

Primers used for the qRTPCR validations.
Fig.S9 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: April 2023

Impact of CXCR3 overexpression in MIA PaCa-2 cells in vitro and in vivo
Supplementary Table S3 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: April 2023

Overall survival based on the expression levels of genes specific to gluconeogenesis and aerobic glycolysis.
Legends for supplementary Figures from Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity
Authors: Ishiguro Tatsuya , Sato Ai , Ohata Hirokazu , Ikarashi Yoshinori , Takahashi Ryou-u , Ochiya Takahiro , Yoshida Masayuki , Tsuda Hitoshi , Onda Takashi , Kato Tomoyasu , Kasamatsu Takahiro , Enomoto Takayuki , Tanaka Kenichi , Nakagama Hitoshi , Okamoto Koji
Published: April 2023

Legends for supplementary Figures 1-5
Supplementary Tables S1-S3 from Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype
Authors: Li Ling , Li Chao , Wang Shaoxin , Wang Zhaohui , Jiang Jian , Wang Wei , Li Xiaoxia , Chen Jin , Liu Kun , Li Chunhua , Zhu Guiquan
Published: April 2023

Summary of small RNA sequencing of hypoxic and normoxic exosomes (S1); Number of miRNA identified in each sample (S2); Characteristics of 108 patients with OSCC and matched volunteers (S3).
Suppl. Figure 6 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

External HGF and conditioned medium leads to alectinib resistance in the EML4-ALK-positive cell line.
Suppl. Figure 5 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

ALK kinase domain sequencing
Supplementary Figure S1 from Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype
Authors: Li Ling , Li Chao , Wang Shaoxin , Wang Zhaohui , Jiang Jian , Wang Wei , Li Xiaoxia , Chen Jin , Liu Kun , Li Chunhua , Zhu Guiquan
Published: April 2023

CD63 immunoblotting of exosomes isolated from normoxic and hypoxic media respectively.
Supplementary Figure S4 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: April 2023

CCL20 and IFN-γ induce IDO expression in CD14+ monocytes.
Supplementary Figure S1 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: April 2023

HIF-1α knockdown prevents hypoxia-induced EMT.
Supplementary Figure Legends from A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers
Authors: Jung MoonSun , Russell Amanda J. , Liu Bing , George Joshy , Liu Pei Yan , Liu Tao , DeFazio Anna , Bowtell David D.L. , Oberthuer André , London Wendy B. , Fletcher Jamie I. , Haber Michelle , Norris Murray D. , Henderson Michelle J.
Published: April 2023

Legends for Supplementary Figures S1-S5.
Supplementary Figure Legends from Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells
Authors: Tang Chih-Hang Anthony , Zundell Joseph A. , Ranatunga Sujeewa , Lin Cindy , Nefedova Yulia , Del Valle Juan R. , Hu Chih-Chi Andrew
Published: April 2023

Legends for Supplementary Figures S1-S13.
Figure S2 from Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer
Authors: Bhat-Nakshatri Poornima , Goswami Chirayu P. , Badve Sunil , Magnani Luca , Lupien Mathieu , Nakshatri Harikrishna
Published: April 2023

Ingenuity pathway analysis of E2-regulated genes dependent on AKT2
Supplementary Figure S4 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

The effect of AIMP2 on TGF-β receptor I stability, Smad2 phosphorylation and TGF-β target gene expression.
Supplementary Figure S2 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

The significance of AIMP2 for Smurf2-dependent downregulation of FBP and the interaction of Smurf2 and FBP.
Supplementary Table S1 from Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP
Authors: Hatzl Stefan , Geiger Olivia , Kuepper Maja Kim , Caraffini Veronica , Seime Till , Furlan Tobias , Nussbaumer Erika , Wieser Rotraud , Pichler Martin , Scheideler Marcel , Nowek Katarzyna , Jongen-Lavrencic Mojca , Quehenberger Franz , Wölfler Albert , Troppmair Jakob , Sill Heinz , Zebisch Armin
Published: April 2023

Primer sequences and/or ordering information used for qPCR analyses.
Supplementary Video from Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors
Authors: Bankson James A. , Walker Christopher M. , Ramirez Marc S. , Stefan Wolfgang , Fuentes David , Merritt Matthew E. , Lee Jaehyuk , Sandulache Vlad C. , Chen Yunyun , Phan Liem , Chou Ping-Chieh , Rao Arvind , Yeung Sai-Ching J. , Lee Mong-Hong , Schellingerhout Dawid , Conrad Charles A. , Malloy Craig , Sherry A. Dean , Lai Stephen Y. , Hazle John D.
Published: April 2023

Animation of the dynamic conversion of hyperpolarized pyruvate into lactate in a murine model of anaplastic thyroid cancer. Heat maps for (left) HP pyruvate and (right) HP lactate overlay T2-weighted MRI. This animation can be estimated with arbitrary temporal resolution following model-based reconstruction from highly undersampled data.