bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison and analysis of field emission characteristics
of carbon cathodes based on PAN fiber and CNT filaments
Authors: Taikin Andrei Yu. , Savichev Ilya A. , Popov Maxim A. , Anokhin Evgeniy M. , Kireev Viktor B. , Kosarev Ilya N. , Sheshin Evgeniy P.
Published: June 2022

In this paper, we experimentally compare the field emission characteristics of two different cathodes based on polyacrylonitrile fibers (PAN fibers) and carbon nanotube fibers (CNT filaments). The main purpose of the study was to compare the field emission properties of materials for the cathode unit of a cathode luminescent lamp. The current-voltage, current and watt-watt characteristics of the fabricated cathodes were measured. A comparison of the current-voltage characteristics of cathodes made of the two studied materials shows that the minimum field for the occurrence of field emission current for a cathode made of a CNT filament (accelerating voltage in the diode version of measurements is about 625 V) is approximately 3 times lower than for a cathode made of PAN fibers (accelerating voltage is about 1850 V. Accordingly, the current value of about 100 μA for a cathode based on a CNT filament is achieved at an accelerating voltage of about 1300 V, and for a cathode based on PAN fibers, about 2630 V. Structural changes in cathodes were studied using scanning electron microscopy methods. Based on the totality of the results, it was concluded that it is preferable to use a CNT filament as a cathode material. The emission current of a cathode based on a CNT filament, when a constant high voltage is applied, demonstrates an increase during the transition period and reaches a stable value of more than 75 μA, apparently due to the activation of additional emission centers when a high accelerating voltage is applied. The paper also analyzes the factors that determine the efficiency of light sources created on the basis of the materials studied in the work.
Public Opinion and Justice
Authors: Shaveko N. A.
Published: June 2022

The article considers the question of whether the legislator should always take into account public opinion. The problems of defining the concept of public opinion are considered: a distinction is made between what people think, say and do. In the context of the Roussoist distinction between the “common will” and the “will of all”, one's own position regarding public opinion is formulated. Further, it is proved that both public opinion and the current legislation are not always fair, while justice as a social ideal takes precedence over both. Hence, it is concluded that legislation, being a form of striving for justice, should not always take into account public opinion.
At the same time, the practical significance of taking into account public opinion in the context of the realization of the ideal of justice, identifying the actual needs of members of society, as well as the moral justification of values and determining the persons authorized for such justification is justified. A distinction is made between public opinion and moral position of society. It is argued that the legislator should take into account both public opinion and the moral position of society, but for different reasons and for different purposes.
Imposing Legal Liability for Violations
in Labor Organization and Labor Management
Authors: Soshnikova T. A. , Slyusarev D. S.
Published: June 2022

The paper considers the types of responsibility of officials (disciplinary, administrative, criminal) in relation to the organization of labor and labor management. It is concluded that it is necessary to improve internal organizational control (audit) to prevent the risks of legal liability.
Epidemiology and diagnostic methods of lumpy skin disease: A Short Review
Authors: Chala Guyassa
Published: June 2022

Lumpy skin disease (LSD) is a severe viral disease that is having an impact on the cattle industry. The disease is now widespread in the majority of African countries, and it has lately expanded beyond the continent into the Middle East area. The disease’s symptoms include an initial period of fever, followed by swollen lymph nodes, circumscribed firm skin nodules, and ulcerative lesions. It occurs in all agroclimatic situations, although it is more common in low-lying areas and beside watercourses. It is transmitted by insect vectors among cattle that share comparable pasture and watering sites and gather in the same barn. In this article, the lumpy skin disease virus, its epidemiology, and diagnostic methods are reviewed.
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IMPLEMENTATION OF EU STANDARDS ON PARENTAL LEAVE IN EU MEMBER STATES AND UKRAINE
Authors:   Taras Shevchenko National University of Kyiv, Sviatun O.
Published: June 2022

The article is devoted to the analysis of the legal nature of the implementation mechanism of the new Council Directive 2019/1158 on work-life balance for parents and carers in EU Member States and compliance of the Ukrainian Legislation with the provisions of this Directive. It is noted that the Directive (EU) 2019/1158 repealed Directive 2010/18/EU and should be transposed into the legal system of Ukraine according to the Association Agreement. The provisions of the Directive 2019/1158 should become legally binding in all EU Member States by August 2022 but as of January 2022 only 4 States have submitted information to the European Commission regarding their transposition measures. Nevertheless, it is underlined that the current legislation in the majority of the EU Member States corresponds to the provisions of the Directive 2019/1158 and sometimes is even more favorable for parents than it is provided by the Directive. Special attention is paid to the assessment of the Ukrainian efforts to bring national legislative provisions in compliance with the EU standards and requirements of the EU-Ukraine Association Agreement.
STOCHASTIC ANALYTICAL APPROACH TO THE TIME FACTOR CONSIDERATION IN ASSETS VALUATION
Authors:   Taras Shevchenko National University of Kyiv, Yakubovsky Valery , Kukush Alexander ,   Taras Shevchenko National University of Kyiv, Yakovlev Mykyta ,   Taras Shevchenko National University of Kyiv
Published: June 2022

This paper emphasizes the important role of assets valuation in assuring the transparency and stability of financial system as underlined by the international Basel Accord on banking supervision. One of the main aspect in this respect is necessity to take into account time factor influence that is especially important for secured lending operations, insurance processes, and in general for investment purposes where duration is essential. Existing approaches for accounting this factor in assets valuation processes are based on empirical analyses of historical data followed by forecasts for the future time period. In this respect two main streamline of approaches are formed: based on smoothing the cyclicity of value change over time or “through cycle” type and skirting of market value evolution trend or “under cycle” type, respectfully. In the paper, a new stochastic analytical model to consider time effect is proposed, which is based on the rational theory of warrant pricing developed by Samuelson. Analytical solution for estimation of proposed time factor Δ is presented. The influence of market value volatility, tendency of market future evolution and required level of certainty on this parameter is analyzed. General methodology of time effect assessment based on this “follow-the-cycle” type model is described. Actual problems of international relations. Issue 150. 2022 48 Testing of the model applicability was demonstrated using the available information data set for the residential apartments market evolution in 2019-2021 in Ukraine which is monitored by consulting-engineering group “Veritex”.
MENTAL IMMUNITY AS BIO-PSYCHO-SOCIO-SPIRITUAL MATRIX OF IDENTITY AND PERSONALITY AND SOCIETY SAFETY BASIS
Authors: Sidorov P I
Published: June 2022

There has been grounded assessment of mental immunity as a bio-psycho-socio-spiritual defense of identity and a basis of personality and society safety. Its resource characteristics and functional mechanisms have been systematized. With the use of the epidemical model of the acquired mental immunodeficiency syndrome, there has been described its phenomenology according to four blocks of psychogenesis and sociogenesis, biogenesis and animogenesis. There have been separated algorithms of arrangement of systemic and block-module protection of public conscience and public health in the hybrid world identity crisis. There has been grounded the synergetic approach to mental safety providing protection of individual and public conscience. Its main directions and target levels in formation of state-civil identity have been separated. We have proposed integral strategies of mental safety provision based on the synergetic technological platform of non-departmental mental health service. We have grounded a mission of mentality medicine consisting of adaptive conscience and health management as a priority of national security in the era of hybrid wars.
BIOCHEMICAL SPECTRUM OF BLOOD SERUM AS INDICATOR OF YAKUTIA RESIDENTS ADAPTEDNESS TO NORTHERN CONDITIONS
Authors: Krivoshapkina Z N , Mironova G E , Semyonova E I , Olesova L D
Published: June 2022

The analysis of lipid metabolism in the population of Yakutia has revealed high percentage of disturbed lipid metabolism both among the indigenous and alien population of Yakutia. The high frequency of dyslipidemia and hypercholesterolemia at the young age in the alien residents of Yakutia is one of the indicators of lower body adaptive reactions. For detection of maladaptation and timely preventive actions, it is necessary to identify informative biochemical methods that characterize body functional states. The sample of 1 422 residents of Yakutia aged 18 to 72 y. o. has been examined. The number of indigenous residents of Yakutia was 758 persons (the mean age 45.02 ± 3.54 years), the alien population - 664 (the mean age 43.67 ± 2.61 years); the women - 878, the men - 544. Dyslipidemia was associated with activity of the enzymes characterizing the body energy needs depending on the degree of adaptedness to climatic and geographical conditions of Yakutia. There have been obtained significant differences of the enzymes activity indicative of different intensity of adaptive metabolic processes in high latitudes depending on ethnicity. During prophylactic medical examinations of the population for identification of disease onset risk groups and development of preventive measures to restore the body reserves, attention should be paid to the serum enzymes activity. De Ritis ratio can serve as one of the criteria of assessment of the body adaptive reactions to uncongenial climatic-geographic factors.
SYNERGETIC BIOPSYCHOSOCIOSPIRITUAL CONCEPTION OF MENTAL EPIDEMIC OF SOMATOFORM DISORDERS
Authors: Sidorov P I , Sovershaeva E P
Published: June 2022

Somatoform disorders (SFD) are notable for their growing prevalence and high latency, a variety of etiopathogenetic factors of developmental trajectories and clinical-dynamic polymodality of pathoplastics and pathokinesis. All this requires development of new approaches to conceptual-methodological support of system struggle against the somatoform mental epidemic. There has been proposed an SFD synergetic biopsychosociospiritual conception, including three prenosological fractals: predisposition - a neurosogenic family, latent - neurosogenic diathesis, initial - primary neurosis, and three nosological fractals: a full-scale clinical picture, chronization and an outcome. There have been specified new resources of the system approach to preventive-correctional and medical-rehabilitation work of mental medicine. Its mission consists in adaptive engineering and management of consciousness and health. Its enables to plan and reconstruct mental immunity as the matrix of identity and security base.
ASSESSMENT OF READINESS OF MEDICAL SCHOOL GRADUATES TO PSYCHO-EDUCATIONAL ACTIVITIES
Authors: Vasilieva E Yur'evna , Tagaeva T V
Published: June 2022

This article describes a method of assessment of readiness of graduates of the medical school to psychological-educational activities based on the factor-criterion model. The model included cognitive, motivational, activity and personal factors and criteria which characterize them. The coefficient values of each factor and the criteria were determined by the Delphi method. Comparison of the criteria with use of the proposed method with the criteria of actual state allowed to perform maximally objective comprehensive assessment of readiness of the graduates to psychological-educational activities. The article has presented the quantitative and qualitative results of the Medical University graduates' self-preparedness for psychological-educational activity. It has been found that the overall level of preparedness of the graduates of the Faculty of General Medicine of the Northern State Medical University to psychological-educational activity corresponded to the nominal level. The teacher's personal example, direct contacts with patients in the course of training at the Medical University, the increased number of hours in the curriculum for studying of the psychological and educational aspects of the "doctor-patient" interaction at the clinical departments have been determined by the graduates of the Medical University as the main factors influencing quality of training for implementation of psychological-educational activity of future doctors. The assessment results can be a basis for correction and improvement of the content, forms and methods of psychological-educational training of future physicians.
EFFICACY OF SPELEOCLIMATOTHERAPY IN STUDENTS UNDER CHRONIC STRESS
Authors: Esaulenko I E , Dorohov E V , Gorbatenko N P , Semiletova V A , Zhogoleva O A
Published: June 2022

The features of neuroimmunoendocrine regulation in junior students under emotional stress associated with the process of learning and assessment of possibilities of speleoclimatotherapy as a method of drug-free correction have been studied. The study involved students of the Voronezh State Medical Academy aged 17 to 20 years. Evaluation of the immune status included: count of lymphocyte subpopulations during flow cytometry using monoclonal antibodies CYTO-STAT tetraCHROME, evaluation of the phagocytic activity of neutrophils - definition of the phagocytic index, of the phagocytic number using a set Phagotest. Myeloperoxidase activity of neutrophils was assessed on the basis of spontaneous and induced tests with NBT (NBT-test), the index of neutrophil activation. The study determined the content of different types of cytokines. The cytokines were determined on the basis of flow cytometry. For study of the autonomic balance, there was evaluated heart rate variability using short segments of ECG recorded during 5 minutes. For determination of emotional stress signs in the subjects, there were used the following psychological tests: the Spielberger - Hanin anxiety test, the Zung anxiety test, the Zung depression test. It has been established that speleoclimatotherapy has possibilities to correct stress-induced changes of parameters of psychovegetative homeostasis and immunity. The biological effect of speleoclimatotherapy is based on the phenomenon of cross-adaptation, the result of which is that adaptation to the microclimate of sylvinite caves is accompanied by an increased resistance to other stress effects. In view of the mechanisms of speleoclimate effect on the neuroimmune system, it is possible to apply speleoclimatotherapy as a non-drug method of integrated prevention and correction of stress-induced disorders among medical students and other persons whose activities are related to chronic emotional stress.
OCCUPATIONAL HEALTH HAZARDS ARISING DURING MINING AND PROCESSING OF APATITE ORES IN KOLA HIGH NORTH
Authors: Syurin S A , Chashchin V P , Shilov V V
Published: June 2022

Despite the ongoing modernization processes, mining and chemical industry workers in the Kola High North continue to be exposed to an increased risk of various health disorders. The aim of the study was to examine the nature and the risks of occupational diseases (OD) and industrial accidents (IA) arising from the use of modern technologies of extraction and processing of apatite-nepheline ores. It has been found that in the OD structure, there dominated musculoskeletal (43.5 cases per 10,000 workers) and nervous (19.0) diseases, as well as hearing loss (17.3). In comparison with other workers, OD were most often (1.39-4.81 times) observed in underground miners. Also, IA cases were more frequently recorded in this group of workers, including fatalities. Thus, our studies have shown that modern methods of extraction of apatite-nepheline ore in the Kola Polar region retained an increased risk of occupational diseases and injuries, especially among underground miners. This causes the need to improve technical and medical interventions for prevention of health problems in this group of workers.
FEATURES OF MEDICAL ASSISTANCE TO VICTIMS WITH COMBINED TRAUMAS CAUSED BY ROAD ACCIDENTS IN SAINT-PETERSBURG
Authors: Tulupov N N , Besaev G M , Sinenchenko G I
Published: June 2022

Specialized medical care to victims of road accidents in St. Petersburg is delivered at 6 level I and 3 level II trauma centers. Annually, each of 6 level I trauma centers gives treatment to about 600 patients, each of 3 level II trauma centers - 10 times less, other hospitals - to about 300 patients. Mortality rate after severe mechanical trauma at the level I trauma centers is about 15%, at the level II trauma centers - about 20% and at other hospitals (not specialized in severe traumas) - 37%. The importance of improvement of the trauma centers financing, the need to deliver patients by mobile resuscitation teams, and other problems have been discussed. The article has shown that St. Petersburg has a better system of medical care of road accident victims than other regions of Russia. The main principles of this system are as follows: early delivery of patients to trauma centers; the need to respect the rules of the "golden hour"; performance of full resuscitation both at the pre-hospital (on the spot and during delivery) and the hospital stage of treatment; the need of examination and treatment of patients regardless of illness severity; opening of anti-shock surgical trauma centers at multi-specialty hospitals providing round-the-clock laboratory, radiation, and endoscopic studies; use of doctors of all specialties; early evaluation of types and severity of injuries according to developed algorithms by using non-invasive, minimally invasive and invasive methods.
MORPHOFUNCTIONAL CHANGES IN LONG-TIME ADAPTATION PROCESS OBSERVED IN NATIVES OF INTERCONTINENTAL AREAS OF RUSSIA’S NORTHEAST
Authors: Averyanova I V , Maximov A L , Vdovenko S I
Published: June 2022

Based on the study of parameters of physical development, cardio-vascular system, external respiration and gas exchange comparative study of 88 young males among European migrants and those born in 1 and 2 generation, natives of continental area of Magadan region was carried. Found that formation of adaptive shifts are typical of some physiological systems of European newcomers; the direction of these shifts does not change in further generations. This fact allow considering it as an organism response of people residing under more extreme conditions of continental natural-climatic area of the region (in comparison with seaside area), when many parameters of functional systems change and weakly depend on duration of residence under such conditions.
ASSESSMENT OF THE PNEUMOCOCCAL VACCINATION PROGRAMME IN MANGISTAU REGION, KAZAKHSTAN
Authors: Karibayeva I K , Aimbetova G E , Amireev S A , Yeraliyeva L T , Kyzayeva A D , Akanov A A , Tulebayev K A , Turdaliyeva B C , Grjibovski A M
Published: June 2022

Pneumonia is one of the main contributors to infant mortality in Kazakhstan. In 2010, Kazakhstan became the first former Soviet republic introduced pneumococcal vaccine into the national immunization scheme. Mangistau region was one of the two first regions where the vaccination became routine from 1 December 2010 using a WHO certified PCV-13 vaccine. The aims of this study were: 1) to assess the number of hospitalizations of children aged 0-5 years for pneumonia in the region before and after introduction of vaccination programme; 2) to compare duration of hospital stay of children with pneumonia before and after introduction of vaccination programme and 3) to compare time between the first visit to medical services and hospitalization of children with pneumonia before and after introduction of vaccination programme. Data to answer these three research questions were analyzed using multivariable negative binomial regression, multiple linear regression and multivariable logistic regression, respectively. All coefficients and odds ratios (OR) are presented with 95 % confidence intervals (CI). We observed a significant reduction of the number of cases of pneumonia by 22 (95 % CI: 6-38) % in 2011 and by 33 (95 % CI: 16-49) % in 2012 compared to 2009. No changes in the duration of hospital stay (β = 0.28; 95 % CI: -0.06; 0.64) or the number of days (0-6 vs. 7 days or more) between the first contact with the healthcare system (OR = 1.0; 95 % ДИ: 0.8-1.2) and hospitalization were found. Our results suggest that the introduction of vaccination against pneumococcal infection contributed to the overall reduction of the number of cases of pneumonia among children aged 0-5 years in Mangistau region, Kazakhstan.
COMBINED CRANIOCEREBRAL AND SKELETAL INJURIES ASSOCIATED WITH ALCOHOL CONSUMPTION
Authors: Firsov S A , Matveev R P , Vilova T V
Published: June 2022

The article has emphasized the problem of injuries related to alcohol consumption. An analysis of contemporary research on this topic and own data have been given. Intoxicated patients had more severe injuries, a more serious course of illness, a greater incidence of complications and mortality. Alcohol intoxication provoked formation of delayed intracranial hematomas. The tendency to form multiple intracranial hematomas and subarachnoid hemorrhages in alcohol abusers was explained by atrophic processes in the brain, subdural spaces extension, toxic lesions of the cerebral vessels. Intoxicated patients should be regarded as a high-risk group in terms of availability of severe traumatic brain injuries, as their condition
RESOURCES AND LINES OF MENTAL PREVENTOLOGY
Authors: Sidorov P I
Published: June 2022

An overriding mental preventology mission in a healthy lifestyle integration and moral purpose of life has been justified in the article. The following instruments and factors of mental resilience were accentuated: neuroplasticity and spirituality, music and signing therapy, dance therapy and physical therapy, somnology and sexual management. A polymodal formula for happiness and multiple logistics of the destiny path abbreviated to SINAPS have been suggested. Major lines of mental preventology have been systematized.
SOCIAL AND PSYCHOLOGICAL ASPECTS OF ADAPTATION OF POLICE OFFICERS OF SPECIAL POLICE SERVICES
Authors: Soloviev A Gorgon'evich , Ichitovkina E G , Zlokazova M V
Published: June 2022

For the purpose of a dynamic analysis of social and psychological adaptation, there have been examined 654 combatants of the Department of the Ministry of Internal Affairs of Russia for the Kirov region. There have been detected features of development of phases of the emotional burnout syndrome and formation of “personality combatant accentuation”. It has been shown that social adaptation of the police officers who underwent medical-psychological rehabilitation and took therapy in connection with borderline mental disorders in anamnesis was positive and was manifested in successful continuation of service, low number of disciplinary infractions, rare alcohol use, stable family interrelations and in whole improvement of the combatants’ adaptation in peaceful conditions of life.
EPIDEMIOLOGY OF HEALTH DISORDERS OF ORPHANS AND CHILDREN WITHOUT PARENTAL CARE
Authors: Davydova N O , Kiyaeva E V , Cheremuschnikova I I , Fomina M V
Published: June 2022

The paper is based on results of a comprehensive examination of 386 children in institutions for orphans and children without parental care including an analysis of registration forms 030/1 12 - 1/u - 2000. The children’s morbidity and disability rates have been studied. Correlations between classes of diseases have been identified. Cluster and discriminative analyses allowed to divide the children into 5 groups according to the morbidity rates and health parameters. A mathematical model has been designed which allowed to refer the children to one of 5 selected groups according to the children’s diseases and a number of other characteristics. The obtained results have substantiated medical treatment and preventive work with children in orphanages.
PECULIARITIES OF ADAPTATION IN YOUNG MALE RESIDENTS OF MAGADAN REGION: ANALYSIS OF INTERSYSTEM FUNCTIONAL RELATIONS (Report 2)
Authors: Sukhanova I V , Maximov A L , Vdovenko S I
Published: June 2022

Based on the methods of correlation and factor analysis of the 21st morphofunctional parameter, there has been performed a comparative study of a sample of 1656 male subjects aged 17-21 y. o. consisting of aborigines, migrants and the 1st and 2nd generations’ Caucasians born in the Magadan region in (enrooted persons). For all the examined subjects, a complex of somatometric indices was the most significant factor specifying the strategy of body long-term adaptation to northern natural and climatic conditions. However, each population has its special morphofunctional ecological portrait which structure is determined by a number of statistically meaningful indices united in a certain number of factors.
RELIGIOUS RESOURCE OF MENTAL MEDICINE
Authors: Sidorov P I
Published: June 2022

In the article, there have been systematized the persisting stress zones between religion and Psychiatry and possibilities of their copability in the framework of the synergetic bio-psycho-socio-spiritual methodology of mental medicine; there have been considered the historical and modern forms of participation of the main religions in mental health promotion and treatment of mental illnesses; complementarity and synthesis of sanogenetic, psychotherapeutic and religious approaches in spiritually integrated medical-rehabilitation and preventive-correctional programs; peculiarities and scales of a new mental phenomenon of «belief without religion»; there has been shown effectiveness of mentally and spiritually integrated therapy; there have been separated directions of realization of the religious resource in mental preventology and Clinical Psychiatry; there have been proved perspective directions of further studies in the field of Psychiatry, mental medicine and religion.
CHOLESTEROL AND RISK OF ATHEROSCLEROSIS IN RURAL INDIGENOUS POPULATION OF REPUBLIC OF SAKHA (YAKUTIA)
Authors: Klimova T M , Fedorova V I , Baltakhinova M E , Krivoshapkin V G
Published: June 2022

According to the results of the cross-sectional study of rural indigenous population of the Republic of Sakha (Yakutia), there has been studied the level of cholesterol and frequency of atherogenic changes of the lipid profile of the blood plasma. It has been found that in 35 % of the surveyed indigenous people, the level of cholesterol was 5.2 mmol/l or more, and in 10.8 % - 6.2 mmol/l or more. Among the persons with high cholesterol, atherogenic changes of the ratio of total cholesterol / HDL-C, LDL-C / HDL-C were observed in 19 % of the men and 8 % of the women (р = 0.014); logarithm (TRG / HDL-C ) - in 11 % of the men and women (p = 0.906). Thus, the high levels of the total cholesterol (5.2 mmol /l or more) in 80 % of the men and in 89% of the women was not accompanied by atherogenic changes in the lipid profile. This allows to consider the status of hypercholesterolemia in this population group in most of the cases as a manifestation of adaptive changes in lipid metabolism. The identified changes in atherogenic lipid profile were associated with presence of metabolic risk factors, what proves the need for determination of cholesterol in lipoprotein composition and a ratio of lipid fractions for choice of a right tactics for correction of the lipid risk factors.
FIVE-YEAR EXPERIENCE OF THROMBOLYTIC THERAPY IN ACUTE ISCHEMIC STROKE IN ARKHANGELSK REGIONAL VASCULAR CENTER
Authors: Saskin V A , Volosevitch A I , Kolygina M R , Krasilnikov S V
Published: June 2022

Background. Thrombolytic therapy (TLT) remains the most effective method for revascularization in acute ischemic stroke (AIS). The aim of our research was to evaluate the efficacy and safety of reperfusion therapy in intravenous TLT in the AIS. Methods. We have analyzed retrospectively medical records of 95 patients with AIS subjected to intravenous TLT with recombinant tissue plasminogen activator (rtPA) within the first 4.5 hours after emergence of symptoms (“therapeutic window”). The average dose of intravenous rtPA was 0.9 mg/kg. All the patients were divided into subgroups according to severity of AIS and age in accordance with WHO criteria. Following the TLT, we evaluated dynamic changes of neurological deficits using the National Institute Health Stroke Scale (NIHSS), rehabilitation levels using the modified Rankin Scale (mRs), as well as incidence of ischemic lesions and hemorrhagic transformation (HT) using CT-scan. Results and Conclusions: We have found that intravenous TLT was beneficial in the subgroups of the patients younger than 60 years, as well as those scored of moderate AIS severity (NIHSS < 14 points). Despite the use of the TLT, disability severity (mRs 4-5 points) increased from 14 to 50 % in parallel with increasing age and severity of the brain damage. The incidence of symptomatic HT following the intravenous TLT corresponded to the international studies results.
ANALYSIS OF ONE AND TWO INDEPENDENT SAMPLES USING STATA SOFTWARE: PARAMETRIC TESTS
Authors: Kharkova O A , Grjibovski A M
Published: June 2022

In this paper we present theoretical principles of the use of one- and two-samples Student’s t-tests. Practical examples are presented with detailed explanations of the use of formulas as well as with step-by-step algorithm on how to use STATA software for comparisons of means in one- and two independent samples with subsequent interpretation of the outputs.
NEW APPROACHES TO EVALUATION OF RUSSIAN FAR EAST COMFORTABILITY FOR POPULATION’S VITAL ACTIVITY
Authors: Bolotin E I , Lubova V A
Published: June 2022

Modern medical-demographic features of the Russian Far East have been analyzed. Its comfortability for the population’s vital activity has been evaluated.
HUMAN ELEMENTAL PORTRAIT: MORBIDITY, DEMOGRAPHY AND PROBLEM OF NATION HEALTH MANAGEMENT
Authors: Agadzhanyan N A , Skalny A V , Detkov V Yu
Published: June 2022

The negative effects of anthropogenic factors (excessive intake of heavy metals, deficit of essential chemicals, adverse climatic and geographical conditions) contribute to reduction of health at individual and population levels. There is a relationship between the basic demographic indices of population of some regions and countries and provision with some essential macro- and trace elements. Moreover, not only the absolute population indices of chemical elements content in hair, but also the relative indices (frequency deviation from the norm) are important biomarkers of demographic status. In the article, a relationship between an exchange of macro-and trace elements and a number of demographic indices has been shown. For example, it has been shown that an increase in prevalence among the population of Fe, Al, K excessive accumulation in men and Cu, Co deficit in women with Mn imbalance at the background can be considered as a negative demographic prognostic factor. Furthermore, calcium-phosphorus metabolism as well as exchange of cobalt correlates with the level of fertility.
ENDOCRINE DISORDERS AND CHANGES IN BONE MINERAL DENSITY IN SEVEROMUISK TUNNEL WORKERS UNDER PROLONGED EXPOSURE TO RADON
Authors: Katamanova E V , Kodinec I N , Abramatec E A , Pavlenko N A , Lakhman O L , Sokolik B N
Published: June 2022

The study included 21 people - employees of the Severomuisk Tunnel. Changes in bone density in the form of the osteopenic syndrome have been detected with use of lumbar spine X-ray osteodensitometry in (44.2 ± 4.8) % of patients. In the analysis of the thyroid endocrine profile indicators, there has been noted an increase in the thyroid-stimulating hormone level in (11.1 ± 2.3) % of cases, an increase in the free triiodothyronine level in (7.4 ± 1.7) % of cases, and its decrease in (3.7 ± 1.2) % of cases, a decrease in the free thyroxine level in (11.1 ± 2.3) %, an increase in the level of antibodies to thyroid peroxidase in (11.1 ± 2.3) % of cases. The received results indicated presence of the osteopenic syndrome in every second trained worker of the Severomuisk Tunnel. The syndrome appearance was caused both by the thyroid gland’s disordered functioning and a complex of unfavorable production factors, such as radon, hard work, an intensive labor process and unfavorable climate
APPLICATION OF GENETIC CRITERIA IN THE OCCUPATIONAL SELECTION OF LABOUR RESOURCES FOR THE OIL FIELDS OF SIBERIA
Authors: Yamkovaya E V , Ilyinskikh N N , Ilyinskikh I N , Ilyinskikh E N
Published: June 2022

225 men employed in the oil industry of the Tomsk and Tyumen Regions of Siberia, the Russian Federation, have been examined. It has been established that the frequency of micronucleated buccal epithelial cells and concentrations of urino-excreted benzapyrene in the workers were significantly higher then in the control group. The highest levels of the indices, including the increased frequency of cells with a large micronucleus (more than 3 pm 2 in diameter), were observed in the individuals with mutant alleles of GSTM1 gene. There has been established a correlation between the frequency of micronucleated cells and the concentrations of benzapyrene in urine. The activation of mutation process in the oil industry workers is presumed to be a result of combined effects of various factors on the genome including not only strong mutagens, but also co-mutagens. It should become a base for implementation of the new, scientifically based criteria for hiring personnel for oil industry works in Siberia.
DIFFERENT VARIANTS OF CARBOHYDRATE METABOLISM DISORDER AND ITS INFLUENCE ON MYOCARDIAL INFARCTION COURSE
Authors: Kholmatova K K , Dvoryashina I V , Supryadkina T V
Published: June 2022

Altogether 360 patients (63.4 % of men) were examined with the aim to reveal the incidence of carbohydrate metabolism disorder and evaluate its influence on the course of myocardial infarction. Of the 292 patients without known diabetes mellitus (DM) type 2 — 31.8 % had prediabetes, and 11.0 % had newly diagnosed DM type 2. Patients with carbohydrate metabolism disorder more often had acute heart failure (AHF Killip II-IV) (40.6 % of patients with normal glycaemia, 55.9 % with prediabetes, 62.6 % and 64.7 % with newly diagnosed and known DM, р = 0.039), and more apparent chronic heart failure (NYHA III-IV) (in 4.2; 9.4; 16.0 and 24.6 % respectively, р < 0.001). Twenty four-hour mortality was higher in patients with known DM type 2 than those without DM (13.2 and 2.3 %, р = 0.008). Regression analysis revealed that impaired glucose metabolism was associated with AHF (Killip II—III (OR = 1.27; 95 % CI: 1.05—1,.54, р = 0.014), Killip IV (OR = 1.39; 95 % CI: 1.06—1.82, р = 0.016)); DM type 2 was associated with higher rate of in-hospital mortality (OR = 4.71; 95 % CI: 2.27—9.78, р < 0.001).
SYSTEM SYNTHESIS OF MENTAL MEDICINE
Authors: Sidorov P I
Published: June 2022

In the article, efficiency of the synergetic approach to development of mental ecology and mental medicine has been grounded on the conceptual-methodological level. It has been shown that quality of life and a health level are 20 % predetermined by the mentality factor. There has been proposed the «Index of personality mental ecology» allowing to take qualitative and quantitative measurements of its biopsychosocial and spiritual-moral potential and to assess and predict a destiny course. There have been systematized the issues of the crisis in psychiatry and the significance of antipsychiatry for a startup of the contemporary Era of Psychotherapy that has made a revolutionary breakthrough to the prenosological field of public health and public conscience and changed radically the focus of the Ψ-mission of the state and the society from mental illnesses to mental health. That has provided dynamic development of the whole complex of neurosciences, forced establishment of social psychiatry and narcology and lead to birth of mental ecology and mental medicine. Separation of mental medicine as a unified theory of mental health promotion and treatment of mental illnesses has been grounded.
CEREBRAL HEMODYNAMICS IN CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER
Authors: Gribanov A V , Melkova L A , Startseva L F
Published: June 2022

The results of the study of cerebral circulation. Rheoen-cephalography method was used. The study involved 99 boys of midchildhood with disorder of attention and hyperactivity disorder and 89 children without pathology. It was found that hyperactive children with attention deficit have decreased cerebral blood flow in the carotid system; reduced elastic properties of vessels of large and medium caliber, increased microcirculatory bloodstream vessels tone in the carotid and in the vertebrobasilar brain basins, impaired venous drainage.
CHARACTERISTICS OF MARRIAGES AND POPULATION REPRODUCTIVE INTENTIONS IN IRKUTSK REGION
Authors: Boyeva A V , Leshchenko Ya A
Published: June 2022

The analysis of the results of the dynamics of processes of marriages and divorces has been represented in this paper and the population reproductive intentions in the Irkutsk Region have been characterized. The study materials testify an increased (from the beginning of 2000s) number of registered marriages and a high level of divorces (during 2007-201 1, the average index was 554.0 divorces per 1 000 marriages). About 40 % of children were born in “civil marriages” (unregistered marriages) or by single mothers each year in the region. The profound sociological studies of youth groups and adult population living in the towns of the Irkutsk Region have shown that most of the respondents were oriented towards formation of families with not many children. Among the interviewed “family” respondents, 64.5 % had one child, and 31.4 % had two children. Among the main causes preventing from realization of their reproductive intentions, the respondents noted financial and housing problems.
ROLE OF ESTIMATION OF EXPOSURE OF CHEMICAL CONTAMINANTS POLLUTING FOODSTUFFS IN ENVIRONMENTAL SAFETY RESEARCH
Authors: Tsareva S A , Krasnova V P , Gryaznova M V
Published: June 2022

There has been estimated exposure of chemical contaminants in samples of poultry of regional producers sold in one of the largest hypermarkets in Ivanovo. Food consumption was studied in a cross-sectional study using the method of 24-hour food reproduction. Priority pollutants of the samples of poultry meat forming the risk of development of non-carcinogenic and carcinogenic effects in the population were nitrates, compounds of lead, cadmium, arsenic and mercury. The exposure value estimated on the basis of the median values for nitrate compounds, lead, cadmium, arsenic, mercury constituted respectively 8.64х10 -2; 1.12х 10 -3; 1.12х 10 -4; 2.80х10 -4; 7.98х10 -6 mg/kg of body weight. The coefficients of risk (HQ) have been calculated according to the prevailing contaminants. A dependence has been found of the decreasing series of heavy metal contamination in poultry meat, which had the following distribution pattern: Pb→ As→ Cd→ Hg.
GEOECOLOGICAL AND SOCIOLOGICAL ANALYSIS OF PROBLEMS OF JUGRA BELOYARSK AREA DEVELOPMENT
Authors: Khaknazarov S Kh
Published: June 2022

In the article, there has been analyzed dynamics of opinions of the inhabitants of the Jugra Beloyarsk area on the results of mining in the region. In particular, environmental problems according to the results of the sociological research conducted in 2003-2005 and 2008 have been considered.
PREDICTORS OF SEVERE ANEMIA PROGRESS IN ELDERLY PATIENTS AFTER ORTHOPEDIC SURGERY
Authors: Borisov D B
Published: June 2022

Anemia is associated with adverse outcomes after surgery, especially in the elderly persons. We have reviewed retrospective data on 435 elderly patients who underwent total hip or knee replacement to establish preoperative risk factors associated with postoperative anemia requiring red blood cell transfusion. The multiple logistic regression analysis was used to identify predictors of allogeneic blood transfusion. Independent risk factors for allogeneic blood transfusion were a low preoperative haemoglobin level, low patient’s weight, revision joint replacements and preoperative intravenous injections of tranexamic acid. Our data allow to assess the risk of postoperative severe anemia and to develop targeted intervention to decrease the risk.
ASSESSMENT OF BIOLOGICAL EFFECT OF DUST OF NON-FERROUS METALS PROCESSING PRODUCTION
Authors: Petrov B A , Onuchina E N , Petrov S B , Tsapoc P I
Published: June 2022

Results of a pilot experiment on studying of biological effect of dust of non-ferrous metals processing production as the least studied pollutant of conglomerations’ atmospheric air have been presented. The experiment was conducted with use of 30 outbread white rats. The studied dust was administered in the experimental animals by the intratracheal way in the dose 6.25 mg per 1.0 ml of on exposition 6 months. The animals of the control group were administered equivalent quantity of normal saline solution. It has been established that biological effect of the dust which was a part of the atmospheric emissions of the non-ferrous metals processing enterprise during chronic influence in small doses, along with the resorptive-toxic effect, was characterized by activation of processes of free radical oxidation, destabilization of the system of antioxidant protection and formation of immunop-athological processes.
CLINICAL AND EPIDEMIOLOGICAL FEATURES OF ROTAVIRUS INFECTIONS IN CHILDREN OF STAVROPOL TERRITORY
Authors: Bezrodnova S M , Aliyeva E V , Gunchenko O V
Published: June 2022

A clinico-epidemiological and laboratory study of 167 patients with different forms of rotavirus infection at the age from 3 months to 17 years was carried out in the period of 2008-201 1. The children with the moderate form of the disease (56.29 %) and the children aged 1-3 years - 74 (44.32 %) - dominated. The children were hospitalized more frequently during the spring months (39.52 %) and in the winter months (29.34 %). The symptoms of the rotavirus infection in children of all ages had peculiarities depending on the forms of the disease; the intoxication, gastroenterological, catarrhal syndromes dominated.
FORMATION OF COLON MICROBIOCENOSIS IN PRETERM INFANTS WITH LOW AND EXTREMELY LOW BIRTH WEIGHT IN HOSPITAL
Authors: Malygina O G , Bazhukova T A , Lobanova E V , Chumakova G N
Published: June 2022

The formation of microbiocenosis of the colon in 58 preterm infants with low and extremely low body weight at the stage of nursing in the Department of Pathology of Newborn and Premature Babies in the Vyzhletsov Arkhangelsk Regional Children’s Clinical Hospital has been studied from October 2009 till June 2011. There have been detected factors influencing formation of microecology of the studied habitat. By the time of discharge from the hospital, the colon microbiocenosis was not formed: a deficit of obligate microflora (bifidobacteria, lactoflora, E. coli) and a high level of enterococci were registered. The hospital stay contributed to contamination of the infants by S. aureus, Enterobacteriaceae and nonfermentative gram-negative microorganisms. The formation of the microbiocenosis was affected by duration of hospitalization, especially in the Intensive Care Unit, a type of feeding and biocorrection with probiotics.
CLIMATE CHANGE AND CONDITIONS OF LIFE IN THE ARCTIC IN PERCEPTION OF NENETS ON ISLAND VAIGACH
Authors: Davydov A N , Mikhailova G V
Published: June 2022

The Arctic climate change influences significantly the environment, economic activity and public health. As the northern peoples, traditions and cultural identity are closely related to the natural environment, any change will have consequences for the society in several ways. Methods: A questionnaire was distributed among the Nenets on Island Vaigach who rely to a large degree on hunting, fishing and reindeer herding for survival. Semi-structured interviews about perception of climate change were also conducted. Results: Climate change was observed and has already had an impact on the Nenets everyday life according to more than 50 % of the respondents. Winter seasons are now colder and longer and summer seasons are colder and shorter than ever. A decrease in the standard of living was noticeable, but few were planning to leave. Conclusion: Climate change has been noticed in the region and it has a negative impact on the standard of living for the Nenets. However, they do not want to leave the Island as cultural identity is important for their overall well-being.
HUMAN ADAPTATION TO HELIOGEOPHYSICAL DISTURBANCES AGAINST THE BACKGROUND OF PRECIPITATING FACTORS
Authors: Babaeva M Iskenderovna , Rogacheva S M , Vishnevskey V V
Published: June 2022

The effect of smoking on the capacity of an organism to adapt to heliogeophysical perturbations was studied. Monitoring data were analyzed using the automatic search of group effects. It has been shown that the cardiovascular system of smoking men was more reactive than the same system of smoking women, and men possessed lower abilities to adapt to the natural and anthropogenic factors effects.
SOME ASPECTS OF PERCEPTION OF HIV/AIDS PREVENTION BY OFFICIALS
Authors: Kuznetsova A A , Neuman L A
Published: June 2022

Perception of HIV/AIDs prevention work by officials has been studied in a qualitative study. Officials of different levels became the subjects of our study. Data collection was performed using the method of individual semi-structured interviews. Key themes for analyzing were: main difficulties of prevention work in the region, trust to information and safe behavior, elements of effective prevention.