bluuebunny/crossref_metadata_2025 huggingface dataset:
Intentional Kinship through Caring Relationships, Heritage, and Identity: Adoptive Parents’ Inclusion of Non-Biological and Non-Affinal Relationships on Family Maps
Authors: Costa Pedro Alexandre , Gubello Alessio , Tasker Fiona
Published: October 2021

Structural open adoption has been beneficial to adoptees in integrating their birth heritage and identity. Adoptive parents also may sometimes seek out others who are neither related biologically nor through partnership to support their child in developing an integrated sense of identity. To what extent do these intentional kinship relationships become incorporated within the adoptive family network and how do adoptive parents view their role in their child’s life? Qualitative data on family inclusion of non-biological and non-affinal kin are reported from interviews with lesbian, gay, bisexual, and heterosexual adoptive parents (n = 25 families). Analyses of verbal and visual data from family map drawing interviews indicated that adoptive parents from the different types of families similarly included intentional kin in their conceptualization of their child’s family. Adopted children’s foster carers, family friends, other adoptive families, and other children and adults were specifically included on family maps to facilitate children’s knowledge of different aspects of their birth heritage and adoption story. The implications of open adoption policy therefore move beyond considerations of only birth family contact. In practice, open adoption procedures convey a broad message to families that appear to widen adoptive parents’ conceptualization of kinship.
COVID-19 Outbreak at a Geriatric Rehabilitation Facility: The Silent Threat of Asymptomatic Patients with High Viral Loads
Authors: Putallaz Pauline , Senn Laurence , Bosshard Wanda , Büla Christophe J.
Published: October 2021

Data about outbreaks of nosocomial COVID-19 disease within geriatric rehabilitation facilities are scarce. In this retrospective case series analysis, we describe such an outbreak, determine the proportion of a-/presymptomatic patients, the median time before symptom onset among presymptomatic patients and investigate whether the viral load differs between patients with and without symptoms. Typical and atypical symptoms were retrieved from the electronic medical records of patients who tested positive for COVID-19 disease during their stay at a 95-bed geriatric rehabilitation facility. The viral load at the time of diagnosis was estimated on cycle threshold values of the rRT-PCR test. Overall, 34 patients (median age, 87 years; range, 66–98; 67% female) tested positive for SARS-CoV-2. During the same period, 19 health care workers were also diagnosed with COVID-19. Among the 27 patients who provided consent, 20 (74%) were symptomatic at the time of testing. Among the remaining seven patients, six developed symptoms after a median of 2 days. A viral load > 106 copies/mL was observed in 20 out of the 27 patients, including five out of the seven initially asymptomatic patients. The rapid transmission of SARS-CoV-2 and the prevalence of initially asymptomatic patients with high viral loads support an extended screening strategy at such facilities.
Pet-Assisted Therapy for Delirium and Agitation in Hospitalized Patients with Neurocognitive Impairment: A Review of Literature
Authors: Sheikh Abu Baker , Javed Nismat , Leyba Katarina , Khair Ali Hamza , Ijaz Zainab , Dar Aimen Asim , Hanif Hamza , Farooq Asif , Shekhar Rahul
Published: October 2021

Delirium leading to agitation is a common issue in elderly people and patients with underlying neurocognitive impairment. Despite use of medications to treat agitation, polypharmacy is a major concern and might lead to multiple side effects in this patient population. Therefore, it is imperative to investigate non-pharmacological methods that can provide solutions to the problem. The objective of this review was to evaluate the impact of pet-assisted therapy on elderly patients, with a major focus on agitation and delirium. For the purposes of this study, a scoping review was performed using PubMed, Google Scholar, and ClinicalTrials. We reviewed literature from 1980 to 2021. Out of the 31 studies reviewed, 14 commented on agitation with respect to pet-assisted interventions. Of these, eight studies (57%) reported a statistically significant reduction in agitation and/or delirium in patients who were exposed to pet therapy. Pet-assisted therapy can improve the standardized care in hospital-based settings for patients with neurocognitive impairment because of better companionship, reduced agitation and mood disorders, and better stability of hemodynamic status. These interventions can pave the way for better patient and hospital satisfaction.
The Importance of Social Support, Positive Identity, and Resilience in the Successful Aging of Older Sexual Minority Men
Authors: Pereira Henrique , Silva Patrícia
Published: October 2021

The aim of this study was to assess the relationship between social support, positive identity, and resilience and the successful aging of older sexual minority men. The study involved having 210 self-identified gay and bisexual men aged between 50 and 80 years complete a cross-sectional online survey comprised of sociodemographic information; the Portuguese version of the Multidimensional Scale of Perceived Social Support; the Lesbian, Gay, and multifactor Bisexual Positive Identity Measure; the Connor–Davidson Resilience Scale 10; and the Successful Aging Perceptions Scale. The results showed that self-identified gay participants showed higher levels of positive identity, while bisexual participants scored higher for resilience, mental health, and successful aging. Higher levels of social support, resilience, and positive identity were significant predictors of mental health (28%), physical health (18%), and successful aging (10%) in our sample. These results offer similarities with the growing body of literature on the positive factors of successful aging in the gay and bisexual men communities, which is an important step in the development of aging and health preventive initiatives among this population.
Aromatherapy Massage vs. Foot Reflexology on the Severity of Restless Legs Syndrome in Female Patients Undergoing Hemodialysis
Authors: Ghasemi Mahbobeh , Rejeh Nahid , Bahrami Tahereh , Heravi-Karimooi Majideh , Tadrisi Seyed Davood , Vaismoradi Mojtaba
Published: October 2021

This study aimed to compare the effects of reflexology and aromatherapy massage on the severity of restless legs syndrome (RLS) in 105 female patients undergoing hemodialysis. A randomized placebo-controlled clinical trial was conducted in a hemodialysis center with 48 beds in a high turnover hospital in an urban area of Iran. Intervention groups received reflexology (n = 35) and aromatherapy massage using lavender essential oil (n = 35) for 24 sessions, and the placebo group (n = 35) received simple foot massage. The restless legs syndrome rating scale was used to assess RLS severity in the groups before the intervention and after 4 and 8 weeks of the interventions. Results obtained by the mixed model analysis 3 * 3 (3 groups * 3 times) revealed the significant effect of time, group, and the time–group interrelationship (p = 0.001). Aromatherapy massage reduced the RLS severity, but reflexology did not appear to cause any significant reduction in it. Therefore, we suggest that aromatherapy massage be incorporated into routine care for relieving the ailment and suffering of patients undergoing hemodialysis.
A Survey of Methodologies for Assessing Mast Cell Density and Activation in Patients with Functional Abdominal Pain Disorders
Authors: Friesen Hunter , Singh Meenal , Singh Vivekanand , Schurman Jennifer V. , Friesen Craig A.
Published: October 2021

The aim was to assess methods utilized in assessing mast cell involvement in functional abdominal pain disorders (FAPDs), specifically to describe variability in methods utilized to assess both mast cell density and activation and determine if a consensus exists. After a literature search identified 70 manuscripts assessing mast cell density, data were extracted including FAPD diagnosis, site of biopsy, selection of microscopic fields analyzed, selection of mucosal region analyzed, method of mast cell identification, method to assess mast cell density, and if performed, method to assess mast cell activation. There appears to be some consensus favoring inmmunohistochemical stains over histochemical stains for identifying mast cells. Otherwise, considerable variability exists in methodology for assessing mast cell density and activation. Regardless of method, approximately 80% of studies found increased mast cell density and/or activation in comparison to controls with no method being superior. A wide variety of methods have been employed to assess mast cell density and activation with no well-established consensus and inadequate data to recommend specific approaches. The current methodology providing physiologic information needs to be translated to a standard methodology providing clinical information with the development of criteria establishing abnormal density and/or activation, and more importantly, predicting treatment response.
A Psychological Perspective on Vicarious Embarrassment and Shame in the Context of Cringe Humor
Authors: Mayer Annalina Valpuri , Paulus Frieder Michel , Krach Sören
Published: October 2021

Cringe humor combines the seemingly opposite emotional experiences of amusement and embarrassment due to others’ transgressions of norms. Psychological theories and empirical studies on these emotional reactions in response to others’ transgressions of social norms have mostly focused on embarrassment and shame. Here, we build on this literature, aiming to present a novel perspective on cringe humor. To do so, we introduce the psychological literature on embarrassment and shame, as well as the processes involved that allow humans to also experience these emotions on behalf of others, and draw theoretical links to cringe comedy. We then systematically disentangle contexts in which audiences experience vicarious embarrassment, and structure our argument based on the ongoing processes and consequences of the observed transgressions of norms based on the constituting dimensions of awareness and intentionality of the normative transgression by the social target. We describe how the behavioral expressions of the target along with the social distance and the current motivations of the audience shape the emotional experience and negotiation of social norms, specifically in response to intentional normative transgressions. While this perspective makes it evident that cringe humor is closely linked to the debate around social normative standards between the actor/actress and the audience, we conclude that the different manifestations and specific situational characteristics have fundamentally different consequences for the affirmation or renegotiation of social normative standards.
Exploring and Monitoring the Reasons for Hesitation with COVID-19 Vaccine Based on Social-Platform Text and Classification Algorithms
Authors: Liu Jingfang , Lu Shuangjinhua , Lu Caiying
Published: October 2021

(1) Background: The COVID-19 pandemic is globally rampant, and it is the common goal of all countries to eliminate hesitation in taking the COVID-19 vaccine and achieve herd immunity as soon as possible. However, people are generally more hesitant about the COVID-19 vaccine than about other conventional vaccines, and exploring the specific reasons for hesitation with the COVID-19 vaccine is crucial. (2) Methods: this paper selected text data from a social platform to conduct qualitative analysis of the text to structure COVID-19 vaccine hesitancy reasons, and then conducted semiautomatic quantitative content analysis of the text through a supervised machine-learning method to classify them. (3) Results: on the basis of a large number of studies and news reports on vaccine hesitancy, we structured 12 types of the COVID-19 vaccine hesitancy reasons. Then, in the experiment, we conducted comparative analysis of three classifiers: support vector machine (SVM), logistic regression (LR), and naive Bayes classifier (NBC). Results show that the SVM classification model with TF-IDF and SMOTE had the best performance. (4) Conclusions: our study structured 12 types of COVID-19 vaccine hesitancy reasons through qualitative analysis, filling in the gaps of previous studies. At the same time, this work provides public health institutions with a monitoring tool to support efforts to mitigate and eliminate COVID-19 vaccine hesitancy.
Electrocardiographic Predictors of Mortality: Data from a Primary Care Tele-Electrocardiography Cohort of Brazilian Patients
Authors: Paixão Gabriela M. M. , Lima Emilly M. , Gomes Paulo R. , Oliveira Derick M. , Ribeiro Manoel H. , Nascimento Jamil S. , Ribeiro Antonio H. , Macfarlane Peter W. , Ribeiro Antonio L. P.
Published: October 2021

Computerized electrocardiography (ECG) has been widely used and allows linkage to electronic medical records. The present study describes the development and clinical applications of an electronic cohort derived from a digital ECG database obtained by the Telehealth Network of Minas Gerais, Brazil, for the period 2010–2017, linked to the mortality data from the national information system, the Clinical Outcomes in Digital Electrocardiography (CODE) dataset. From 2,470,424 ECGs, 1,773,689 patients were identified. A total of 1,666,778 (94%) underwent a valid ECG recording for the period 2010 to 2017, with 1,558,421 patients over 16 years old; 40.2% were men, with a mean age of 51.7 [SD 17.6] years. During a mean follow-up of 3.7 years, the mortality rate was 3.3%. ECG abnormalities assessed were: atrial fibrillation (AF), right bundle branch block (RBBB), left bundle branch block (LBBB), atrioventricular block (AVB), and ventricular pre-excitation. Most ECG abnormalities (AF: Hazard ratio [HR] 2.10; 95% CI 2.03–2.17; RBBB: HR 1.32; 95%CI 1.27–1.36; LBBB: HR 1.69; 95% CI 1.62–1.76; first degree AVB: Relative survival [RS]: 0.76; 95% CI0.71–0.81; 2:1 AVB: RS 0.21 95% CI0.09–0.52; and RS 0.36; third degree AVB: 95% CI 0.26–0.49) were predictors of overall mortality, except for ventricular pre-excitation (HR 1.41; 95% CI 0.56–3.57) and Mobitz I AVB (RS 0.65; 95% CI 0.34–1.24). In conclusion, a large ECG database established by a telehealth network can be a useful tool for facilitating new advances in the fields of digital electrocardiography, clinical cardiology and cardiovascular epidemiology.
Computer Assisted Patient Monitoring: Associated Patient, Clinical and ECG Characteristics and Strategy to Minimize False Alarms
Authors: Pelter Michele M. , Mortara David , Badilini Fabio
Published: October 2021

This chapter is a review of studies that have examined false arrhythmia alarms during in-hospital electrocardiographic (ECG) monitoring in the intensive care unit. In addition, we describe an annotation effort being conducted at the UCSF School of Nursing, Center for Physiologic Research designed to improve algorithms for lethal arrhythmias (i.e., asystole, ventricular fibrillation, and ventricular tachycardia). Background: Alarm fatigue is a serious patient safety hazard among hospitalized patients. Data from the past five years, showed that alarm fatigue was responsible for over 650 deaths, which is likely lower than the actual number due to under-reporting. Arrhythmia alarms are a common source of false alarms and 90% are false. While clinical scientists have implemented a number of interventions to reduce these types of alarms (e.g., customized alarm settings; daily skin electrode changes; disposable vs. non-disposable lead wires; and education), only minor improvements have been made. This is likely as these interventions do not address the primary problem of false arrhythmia alarms, namely deficient and outdated arrhythmia algorithms. In this chapter we will describe a number of ECG features associated with false arrhythmia alarms. In addition, we briefly discuss an annotation effort our group has undertaken to improve lethal arrhythmia algorithms.
The Medieval Town of Óbidos (Portugal): Restoration, Reutilisation and Tourism Challenges from 1934 to the Present Day
Authors: Soares Clara Moura , Neto Maria João
Published: October 2021

Heritage conservation and cultural tourism are central features of academic debates, as this relationship has not been always peaceful. This paper seeks to evaluate the correlation between the extensive conservation and restoration of the wall and castle of the medieval town of Óbidos (1930–1950) and the tourism-oriented projects developed since this period. Due to the criticism of several previous studies, one of the primary aims of this research was to assess whether this Portuguese town constitutes a good example of medieval reconstitution, or if it is a fanciful twentieth-century intervention. Another main goal was to establish our position regarding the challenges inherent to the management of this historic centre, especially those concerning current tourism challenges and the preservation of and regard for historical buildings and monuments. By means of a long-term study based on the common history of art methodology (cross-analysis of bibliography, archival research, in situ observation of the heritage and attendance of festivals and events), we were able to make the following contributions to advance the debate: although the earlier interventions in Óbidos abided by strict criteria which merited international praise, the management model of the town as a tourist destination over the last two decades calls for a revaluation, placing greater importance on history, historic and artistic heritage and the identity of the location.
Complex Relationships: A Materials Study of Édouard Vuillard’s Interior, Mother and Sister of the Artist
Authors: Haddad Abed , Hartman Diana , Martins Ana
Published: October 2021

Édouard Vuillard (1868–1949) is well known for his small atmospheric paintings, often portraying his own home and family as the subject matter. Interior, Mother and Sister of the Artist (1893) underwent at least one restoration treatment before being acquired by the Museum of Modern Art (MoMA) in 1934. The painting was treated again in 1954, but no analysis was carried out to understand the artist’s methods and materials at that time. To better understand the choices of Vuillard in Interior, Mother and Sister of the Artist, a comprehensive suite of imaging and spectroscopic analyses was undertaken, including: XRR, UVF and IRR Photography, XRF, Raman spectroscopy and SERS, and µ-FTIR. Statistical analysis on the XRF data using MCR-ALS further revealed some of the intricacies of Vuillard’s technique and color choices, where a large number of pigments were used in designing this intimate composition, including lead white, zinc white, bone black, ochre, umber, vermilion, Geranium lake, red lead, ultramarine, Prussian blue, chrome yellow, chrome orange, zinc yellow, strontium yellow, cadmium yellow, and a chromium oxide green.
Underground Built Heritage (UBH) as Valuable Resource in China, Japan and Italy
Authors: Varriale Roberta , Genovese Laura
Published: October 2021

Recent research about the theoretical approach to elements of cultural heritage that can be included in the newly born class Underground Built Heritage (UBH), has provided several instruments for the functional classification and the static and dynamic analysis of all artefacts coherent with the given definition, while introducing several criteria for their reuse and the evaluation of connected enhancement processes as well. These guidelines can be adopted to analyze single artefacts, groups of homogenous or heterogeneous elements, and also selected territorial assets or national systems, even at a comparative level. With reference to this potential, research results from the application of this new methodological approach to the outputs of three ongoing projects by the National Research Council of Italy, all focusing on UBH, in three countries: China, Japan and Italy, are presented. With reference to the above-mentioned geographical contests, the research introduces a comparative study focusing on selected examples of artefacts that have been historically built underground to manage three functions: living space, religion and economy. This study, carried out based on data collected during onsite visits by the authors, consists in three steps: selection and analysis of case studies, definition of level of reuses on the basis of a given scale, and analysis of the different tools adopted for their conservation and enhancement. In the conclusions, possible future implementations of reuses of the analyzed elements are pointed out.
Effect of Cold Stress on Growth, Physiological Characteristics, and Calvin-Cycle-Related Gene Expression of Grafted Watermelon Seedlings of Different Gourd Rootstocks
Authors: Lu Kaixing , Sun Jiutong , Li Qiuping , Li Xueqin , Jin Songheng
Published: October 2021

Recently, grafting has been used to improve abiotic stress resistance in crops. Here, using watermelon ‘Zaojia 8424’ (Citrullus lanatus) as scions, three different gourds (Lagenaria siceraria, 0526, 2505, and 1226) as rootstocks, and non-grafted plants as controls (different plants were abbreviated as 0526, 2505, 1226, and 8424), the effect of cold stress on various physiological and molecular parameters was investigated. The results demonstrate that the improved cold tolerance of gourd-grafted watermelon was associated with higher chlorophyll and proline content, and lower malondialdehyde (MDA) content, compared to 8424 under cold stress. Furthermore, grafted watermelons accumulated fewer reactive oxygen species (ROS), accompanied by enhanced antioxidant activity and a higher expression of enzymes related to the Calvin cycle. In conclusion, watermelons with 2505 and 0526 rootstocks were more resilient compared to 1226 and 8424. These results confirm that using tolerant rootstocks may be an efficient adaptation strategy for improving abiotic stress tolerance in watermelon.
Performance of Thermal Insulation Covering Materials to Reduce Postharvest Losses in Okra
Authors: Rattanakaran Jutarat , Saengrayap Rattapon , Aunsri Nattapol , Padee Sirada , Prahsarn Chureerat , Kitazawa Hiroaki , Bishop Chris F. H. , Chaiwong Saowapa
Published: October 2021

The efficiency of different thermal insulation covers in minimizing temperature fluctuations in cool chain management was investigated to reduce postharvest loss and maintain okra quality during storage and transportation. The four thermal insulation covering materials: (1) heat reflective sheet with thin nonwoven (HRS + TNNW), (2) heat reflective sheet with thick nonwoven (HRS + TKNW), (3) metalized Tyvek® (MTyvek) and (4) metalized foam sheet (MFS) were studied and compared with perforated linear low-density polyethylene (P-LLDPE) as the typical handing package for okra distribution alongside no covering as the control. The material properties, transpiration rate, vital heat, temperature profiles (air and pulp temperatures), relative humidity, mass loss and incidence of decay were determined throughout a simulated supply chain. Results exhibited that HRS + TNNW and HRS + TKNW covers had the lowest thermal heat energy (Qx) and moderate R-value. These two covers maintained low temperature fluctuation with the lowest rate of air and pulp temperature changes, reflecting in lowest mass loss and decay in okra. The HRS + TNNW cover yielded less decay (1%) in okra, compared to commercial covers; MTyvek (16%) and MFS (9%). Results showed that HRS + TNNW exhibited great potential as a thermal insulation cover to reduce postharvest loss in okra (5%) compared to typical handling (11–18%) and could be considered as alternative material to reduce the use of foam sheets in cool chain management distribution packaging of okra under ambient environment conditions.
Morpho-Anatomical and Biochemical Characterization of Embryogenic and Degenerative Embryogenic Calli of Phoenix dactylifera L.
Authors: Zein El Din Amal F. M. , Abd Elbar Ola H. , Al Turki Saleh M. , Ramadan Khaled M. A. , El-Beltagi Hossam S. , Ibrahim Hemmat A. , Gadalla Ezzeldin G. , Shams El-Din Ibrahim M. , Ibrahim Ibrahim S. , Farag Reham , Ibrahim Mohamed F. M. , Abd El-Aal Mona S. , El-Yazied Ahmed Abou , El-Mogy Mohamed M. , Samaan Mina S. F. , Abdellatif Yasmin M. R.
Published: October 2021

The study of morpho-anatomical aspects, metabolic changes of proteins, antioxidant substances, as well as phenolic compounds in embryogenic callus (EC) and degenerative embryogenic callus (DEC) was the aim of the present investigation. Ability to form somatic embryos (SEs) was associated with the softness of the EC, which exhibited a white or creamy color and was composed of isodiametric cells containing dense cytoplasm, conspicuous nuclei and minimal vacuoles with observed mitotic activity. Furthermore, protein, reduced glutathione (GSH) and ascorbic acid (ASC) concentrations and the ratio between ASC and dehydroascorborbic acid (DHA) were increased significantly in the EC in comparison to the DEC. In addition, the phenolic extract of the EC was proved to have higher scavenging activity than the extract from the DEC. A loss of embryogenic competence in the DEC was correlated with the presence of more rigid clumps and such calli had a yellowish to brown color and no cell division could be observed in the cells of such aggregates as the cells had large vacuoles and they have very thick walls. Moreover, these morphological and anatomical observations of the DEC were accompanied by accumulations of the oxidized form of ascorbic acid (DHA), H2O2, total soluble phenolic compounds and overaccumulation of naringenin. Alternations in cellular metabolism can affect and regulate the morphogenesis of somatic embryos.
Estimation of Peak Discharges under Different Rainfall Depth–Duration–Frequency Formulations
Authors: Gioia Andrea , Lioi Beatrice , Totaro Vincenzo , Molfetta Matteo Gianluca , Apollonio Ciro , Bisantino Tiziana , Iacobellis Vito
Published: October 2021

One of the main signatures of short duration storms is given by Depth–Duration–Frequency (DDF) curves. In order to provide reliable estimates for small river basins or urban catchments, generally characterized by short concentration times, in this study the performances of different DDF curves proposed in literature are described and compared, in order to provide insights on the selection of the best approach in design practice, with particular reference to short durations. With this aim, 28 monitoring stations with time series of annual maximum rainfall depth characterized by sample size greater than 20 were selected in the Northern part of the Puglia region (South-Eastern Italy). In order to test the effect of the investigated DDF curves in reproducing the design peak discharge corresponding to an observed expected rainfall event, the Soil Conservation (SCS) curve number (CN) approach is exploited, generating peak discharges according to different selected combinations of the main parameters that control the critical rainfall duration. Results confirm the good reliability of the DDF curves with three parameters to adapt on short events both in terms of rainfall depth and in terms of peak discharge and, in particular, for durations up to 30 min, the three-parameter DDF curves always perform better than the two-parameter DDF.
Psychological Impacts of COVID-19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package
Authors: Blake Holly , Mahmood Ikra , Dushi Gonxhe , Yildirim Mehmet , Gay Elizabeth
Published: October 2021

We explore the impact of COVID-19 on the psychological wellbeing of healthcare trainees, and the perceived value of a digital support package to mitigate the psychological impacts of the pandemic (PoWerS Study). This mixed–methods study includes (i) exposure to a digital support package; (ii) participant survey to assess wellbeing, perceptions of work and intervention fidelity; (iii) semi–structured qualitative interviews. Interviews were digitally recorded and transcribed, data were handled and analysed using principles of thematic framework analysis. Participants are 42 health and medical trainees (9M, 33F) from 13 higher education institutions in the UK, studying during the COVID-19 pandemic. Survey findings showed high satisfaction with healthcare training (92.8%), but low wellbeing (61.9%), moderate to high perceived stressfulness of training (83.3%), and high presenteeism (50%). Qualitative interviews generated 3 over–arching themes, and 11 sub–themes. The pandemic has impacted negatively on emotional wellbeing of trainees, yet mental health is not well promoted in some disciplines, and provision of pastoral support is variable. Disruption to academic studies and placements has reduced perceived preparedness for future clinical practice. Regular check–ins, and wellbeing interventions will be essential to support the next generation health and care workforce, both in higher education and clinical settings. The digital support package was perceived to be accessible, comprehensive, and relevant to healthcare trainees, with high intervention fidelity. It is a useful tool to augment longer–term provision of psychological support for healthcare trainees, during and after the COVID-19 pandemic.
Factors Associated with Intention of Serbian Public Health Workers to Leave the Job: A Cross-Sectional, Population-Based Study
Authors: Tripković Katica , Šantrić-Milićević Milena , Vasić Milena , Živković-Šulović Mirjana , Odalović Marina , Mijatović-Jovanović Vesna , Bukumirić Zoran
Published: October 2021

Recruitment and retention of public health workers (PHWs) is crucial for the optimal functioning of the public health system at a time of budget cuts and the threat of a pandemic. Individual and job-related variables were examined by univariate and multivariate logistic regression to identify predictors of the intention to leave a job during the COVID-19 outbreak among Serbian PHWs in 25 institutes of public health (n = 1663 respondents, of which 73.1% were female). A total of 20.3% of PHWs intended to leave their current job within the next five years. Males and persons aged younger than 55 years who had additional practice were more likely to report an intention to leave their job than females, those older than 54 years and those without additional work. While uncertainty and fear of infection during the COVID-19 pandemic were almost perceived as job attractiveness, other job-related characteristics were identified as significant barriers to maintaining the sufficient capacity of qualified PHWs in the future. Authorities need to address these factors, including the following: the feeling of tension, stress or pressure, and unavailability of information during the COVID-19 pandemic, as well as dissatisfaction with respect, valuation, and the job in general.
The Impact of the COVID-19 Pandemic on Poles’ Nutritional and Health Behaviour and Quality of Life—A Pilot Study
Authors: Raczkowska Ewa , Mazurkiewicz Dominika , Ambrozik-Haba Jagoda , Godyla-Jabłoński Michaela
Published: October 2021

The coronavirus (COVID-19) pandemic, which has lasted for over a year, has affected everyone’s lives. It is interesting to examine how populations cope with the new situation and to learn about the impact of the epidemic on quality of life. The aim of this study was to assess the impact of the COVID-19 pandemic on changes in selected elements of lifestyle compared to the pre-pandemic period among adult Polish residents. The impact of the COVID-19 pandemic on selected features of quality of life was examined. It was found that, for some distinguishing factors (i.e., quality of life, health status and sleep quality), there were no statistically significant differences. Other distinguishing factors (i.e., ability to perform daily living activities, ability to work and personal relationships) were statistically different. Another part of the study was to assess changes in the frequency of consumption of specific food groups. The vast majority of respondents declared no changes in the frequency of consumption of selected food products. The majority of respondents declared that the COVID-19 pandemic did not cause a change in the frequency of drug use (i.e., cigarettes, alcohol and coffee).
A Systematic Review on Caries Status of Older Adults
Authors: Chan Alice Kit Ying , Tamrakar Manisha , Jiang Chloe Meng , Lo Edward Chin Man , Leung Katherine Chiu Man , Chu Chun Hung
Published: October 2021

The aim of this systematic review was to provide an update on caries prevalence in older adults aged 60 years or above around the globe. Two independent reviewers performed a systematic literature search of English publications from January 2016 to December 2020 using Pubmed, Scopus, Embase/Ovid and Web of Science. The MeSH terms used were “dental caries”, “root caries”, “DMF index”, “aged” and “aged 80 and over”. Further searches in Google Scholar retrieved eight additional publications. The epidemiological surveys reporting the prevalence of dental caries or root caries or caries experience using DMFT (decayed, missing and filled teeth) and DFR (decayed and filled root) in older adults aged 60 years or above were included. Quality of the publications was assessed using the JBI Critical Appraisal Checklist for Studies Reporting Prevalence Data. Among the 5271 identified publications, 39 articles of moderate or good quality were included. Twenty studies were conducted in Asia (China, India, Vietnam, Singapore and Turkey), ten in Europe (Ireland, Norway, Finland, Germany, Portugal, Poland, Romania and Kosovo), three in North America (USA and Mexico), one in South America (Brazil), two in Oceania (Australia) and three in Africa (Malawi, Egypt and South Africa). The prevalence of dental caries ranged from 25% (Australia) to 99% (South Africa), while the prevalence of root caries ranged from 8% (Finland) to 74% (Brazil) in community dwellers. The situation was even worse in institutionalised older adults of which the mean DMFT score varied from 6.9 (Malawi) to 29.7 (South Africa). Based on the included studies published in the last 5 years, caries is still prevalent in older adults worldwide and their prevalence varies across countries.
Coordination Study on Ecological and Economic Coupling of the Yellow River Basin
Authors: Zhao Yanhong , Hou Peng , Jiang Jinbao , Zhai Jun , Chen Yan , Wang Yongcai , Bai Junjun , Zhang Bing , Xu Haitao
Published: October 2021

The coupling and coordination relationship between ecology and the economy in the Yellow River Basin is a hot topic in sustainable development research. Said research has important guiding significance for the ecological security and comprehensive development of the Yellow River Basin. Taking the Yellow River Basin as the object of our study, based on the data of the economy, energy consumption data, ecology data and water resources data, we construct an indicator system of the economic development and ecological status of the Yellow River Basin and use the principal component analysis method to calculate the economic development and ecological status index. Then, we use the evaluation method, the coupling degree model and the coupling coordination degree model to analyze the time and space evolution trends of economic development and ecological state, coupling degree and coupling coordination degree. The results show that: (1) From 2000 to 2018, the economic development index of the Yellow River Basin rose steadily; the ecological status index showed a slow rise and then a downward trend. (2) The degree of coupling between economic development and ecological state has been considered as intensity coupling after 2005. The coupling trend slowly increased and then decreased, indicating that the interaction effect between the economy and ecology was first significantly enhanced and then slowly weakened. (3) The degree of coupling coordination increased from 0.2994 to 0.6266 and then decreased to 0.5917, reflecting the continuous improvement of the relationship between the regional economy and the ecological environment and the trend toward coordination. From 2015 to 2018, due to the gradual increase in the difference between economic development and ecological conditions, the coupling and coordination between the two decreased. Studies have shown that ecological construction and protection should be strengthened to ease the contradiction between the economy and ecology and achieve coordinated development.
A Qualitative Study Exploring the Management of Medicine Shortages in the Community Pharmacy of Pakistan
Authors: Omer Sumaira , Ali Salamat , Shukar Sundus , Gillani Ali Hassan , Fang Yu , Yang Caijun
Published: October 2021

Managing medicine shortages consumes ample time of pharmacists worldwide. This study aimed to explore the strategies and resources being utilized by community pharmacists to tackle a typical shortage problem. Qualitative face-to-face interviews were conducted. A total of 31 community pharmacists from three cities (Lahore, Multan, and Dera Ghazi Khan) in Pakistan were sampled, using a purposive approach. All interviews were audio taped, transcribed verbatim, and subjected to thematic analysis. The analysis yielded five broad themes and eighteen subthemes. The themes highlighted (1) the current scenarios of medicine shortages in a community setting, (2) barriers encountered during the shortage management, (3) impacts, (4) corrective actions performed for handling shortages and (4) future interventions. Participants reported that medicine shortages were frequent. Unethical activities such as black marketing, stockpiling, bias distribution and bulk purchasing were the main barriers. With respect to managing shortages, maintaining inventories was the most common proactive approach, while the recommendation of alternative drugs to patients was the most common counteractive approach. Based on the findings, management strategies for current shortages in community pharmacies are insufficient. Shortages would continue unless potential barriers are addressed through proper monitoring of the sale and consumption of drugs, fair distribution, early communication, and collaboration.
Evaluation of Feature Selection Techniques for Breast Cancer Risk Prediction
Authors: López Nahúm Cueto , García-Ordás María Teresa , Vitelli-Storelli Facundo , Fernández-Navarro Pablo , Palazuelos Camilo , Alaiz-Rodríguez Rocío
Published: October 2021

This study evaluates several feature ranking techniques together with some classifiers based on machine learning to identify relevant factors regarding the probability of contracting breast cancer and improve the performance of risk prediction models for breast cancer in a healthy population. The dataset with 919 cases and 946 controls comes from the MCC-Spain study and includes only environmental and genetic features. Breast cancer is a major public health problem. Our aim is to analyze which factors in the cancer risk prediction model are the most important for breast cancer prediction. Likewise, quantifying the stability of feature selection methods becomes essential before trying to gain insight into the data. This paper assesses several feature selection algorithms in terms of performance for a set of predictive models. Furthermore, their robustness is quantified to analyze both the similarity between the feature selection rankings and their own stability. The ranking provided by the SVM-RFE approach leads to the best performance in terms of the area under the ROC curve (AUC) metric. Top-47 ranked features obtained with this approach fed to the Logistic Regression classifier achieve an AUC = 0.616. This means an improvement of 5.8% in comparison with the full feature set. Furthermore, the SVM-RFE ranking technique turned out to be highly stable (as well as Random Forest), whereas relief and the wrapper approaches are quite unstable. This study demonstrates that the stability and performance of the model should be studied together as Random Forest and SVM-RFE turned out to be the most stable algorithms, but in terms of model performance SVM-RFE outperforms Random Forest.
Training Early Childhood Teachers to Support Children’s Social and Emotional Learning: A Preliminary Evaluation of Roundies Program
Authors: Moazami-Goodarzi Ali , Zarra-Nezhad Maryam , Hytti Maija , Heiskanen Nina , Sajaniemi Nina
Published: October 2021

(1) Background: Implementing social-emotional learning (SEL) programs in Early Childhood Education (ECE) settings is a promising approach that can strengthen overall development and well-being during childhood and into adolescence and adulthood. This study described the development, implementation, and preliminary evaluation of a universal SEL program, i.e., Roundies, in the Finnish ECE context to address the need for professional development opportunities. (2) Methods: The Roundies program was a quasi-experimental pre-test/post-test with intervention and control design. A total of 194 children were assigned to either the intervention group (n = 136) or control group (n = 58) (MAGE = 60.35 months at pre-test; 48% boys). Teachers rated the children’s behaviors using the Strength and Difficulties Questionnaire (SDQ) at the pre-and post-test. (3) Results: Feedback collected by teachers on the program suggested that teachers were highly satisfied with the overall program and the components. Multilevel models showed significantly increased prosocial behaviors and reduced SDQ total difficulties in the intervention group compared to the control group. (4) Conclusions: These preliminary findings provide evidence of the effectiveness of the Roundies program in improving teachers’ capacity to support early SEL.
Symptoms of Autism, Comorbid Mental Health Conditions and Challenging Behaviors among Toddlers with Down Syndrome at Low Risk for ASD—Characterization Using the BISCUIT—Parts 1–3
Authors: Pisula Ewa , Niedźwiecka Alicja
Published: October 2021

Background: Autism spectrum disorder (ASD) may coexist with Down syndrome (DS). Most studies on this topic involve school-age children, adolescents, or adults with DS. This study looked at ASD symptoms, other mental health problems, and challenging behaviors in toddlers with DS at low risk of ASD. Methods: We used screening tools for autism in toddlers; BISCUIT–Parts 1–3 and Q-CHAT. We compared four groups of children aged 17–37 months: DS, ASD, Atypical Development (AD), and Typically Developing (TD). Results: Children with DS showed lower symptoms of ASD than children with ASD (without DS) and higher than TD children, except for repetitive behaviors/restricted interests. For comorbid mental health problems and difficult behaviors, children with DS scored lower than children with ASD. There were no differences between children with DS and TD children in this regard. Conclusions: The study results indicate that BISCUIT–Parts 1–3 are valid instruments to differentiate toddlers with DS from toddlers with ASD. However, they also show that toddlers with DS at low ASD risk are a very heterogeneous group when the ASD symptoms are considered. Autistic characteristics should be taken into account in supporting young children with this genetic condition.
Systematic Knowledge Management of Construction Safety Standards Based on Knowledge Graphs: A Case Study in China
Authors: Jiang Yukun , Gao Xin , Su Wenxin , Li Jinrong
Published: October 2021

Construction safety standards (CSS) have knowledge characteristics, but few studies have introduced knowledge graphs (KG) as a tool into CSS management. In order to improve CSS knowledge management, this paper first analyzed the knowledge structure of 218 standards and obtained three knowledge levels of CSS. Second, a concept layer was designed which consisted of five levels of concepts and eight types of relationships. Third, an entity layer containing 147 entities was constructed via entity identification, attribute extraction and entity extraction. Finally, 177 nodes and 11 types of attributes were collected and the construction of a knowledge graph of construction safety standard (KGCSS) was completed using knowledge storage. Furthermore, we implemented knowledge inference and obtained CSS planning, i.e., the list of standard work plans used to guide the development and revision of CSS. In addition, we conducted CSS knowledge retrieval; a process which supports interrogative input. The construction of KGCSS thus facilitates the analysis, querying, and sharing of safety standards knowledge.
Buy Now and Pay (Dearly) Later: Unraveling Consumer Financial Spinning
Authors: Mesly Olivier
Published: October 2021

In this challenging and innovative article, we propose a framework for the consumer behavior named “consumer financial spinning”. It occurs when borrowers-consumers of products with high financial stakes accumulate unsustainable debt and disconnect from their initial financial hierarchy of needs, wealth-related goals, and preferences over their household portfolio of assets. Three behaviors characterize daredevil consumers as they spin their wheel of misfortune, which together form a dark financial triangle: overconfidence, use of rationed rationality, and deceitfulness. We provokingly adapt some of the tenets of the Markowitz and Capital Asset Pricing models in the context of the predatory paradigm that consumer financial spinning entails and use modeling principles from the data percolation methodology. We partially test the proposed framework and show under what realistic conditions the relationship between expected returns and risk may depart from linearity. Our analysis and results appear timely and important because a better understanding of the psychological conditions that fuel intense speculation may restrain market frictions, which historically have kept reappearing and are likely to reoccur on a regular basis.
Initial Step of Selenite Reduction via Thioredoxin for Bacterial Selenoprotein Biosynthesis
Authors: Shimizu Atsuki , Tobe Ryuta , Aono Riku , Inoue Masao , Hagita Satoru , Kiriyama Kaito , Toyotake Yosuke , Ogawa Takuya , Kurihara Tatsuo , Goto Kei , Prakash N. Tejo , Mihara Hisaaki
Published: October 2021

Many organisms reductively assimilate selenite to synthesize selenoprotein. Although the thioredoxin system, consisting of thioredoxin 1 (TrxA) and thioredoxin reductase with NADPH, can reduce selenite and is considered to facilitate selenite assimilation, the detailed mechanism remains obscure. Here, we show that selenite was reduced by the thioredoxin system from Pseudomonas stutzeri only in the presence of the TrxA (PsTrxA), and this system was specific to selenite among the oxyanions examined. Mutational analysis revealed that Cys33 and Cys36 residues in PsTrxA are important for selenite reduction. Free thiol-labeling assays suggested that Cys33 is more reactive than Cys36. Mass spectrometry analysis suggested that PsTrxA reduces selenite via PsTrxA-SeO intermediate formation. Furthermore, an in vivo formate dehydrogenase activity assay in Escherichia coli with a gene disruption suggested that TrxA is important for selenoprotein biosynthesis. The introduction of PsTrxA complemented the effects of TrxA disruption in E. coli cells, only when PsTrxA contained Cys33 and Cys36. Based on these results, we proposed the early steps of the link between selenite and selenoprotein biosynthesis via the formation of TrxA–selenium complexes.