bluuebunny/crossref_metadata_2025 huggingface dataset:
Egalitarian Pluralism
Authors: Teles Steven M.
Published: February 2023

Alison Gopnik makes a compelling case for care as a matter of social responsibility. A politics of care, however, must address who has the authority to determine the content of care, not just who pays for it. The most attractive ideological vision of a politics of care combines extensive redistribution with a pluralistic recognition of the many different arrangements through which care is provided.
Mutual Aid as Spiritual Sustenance
Authors: Miller Michelle
Published: February 2023

The reemergence of fraternal and mutual aid structures across multiple sectors of the economy is a product of a unifying working-class cultural identity related to precarity. These experiments with collective economic self-reliance reveal what future forms of labor institutions may look like, demonstrating the transformative potential of building community through mutual care.
Supply Chains & Working Conditions During the Long Pandemic: Lessons for a New Moral Political Economy?
Authors: Locke Richard M. , Armstrong Ben , Schaab-Rozbicki Samantha , Young Geordie
Published: February 2023

In recent decades, the global economy has become increasingly structured around supply chains that connect firms within and across national borders, a reliance that has been the subject of controversy in light of disruptions from the COVID-19 pandemic. In response to these disruptions, firms have adapted in various ways to maintain their level of production. In this essay, we describe two approaches companies pursued during the pandemic: the “sweating” strategy in which firms shifted costs onto the worker, and the “securing” strategy in which firms chose instead to invest resources into supporting their workforce. In doing so, we argue that the companies’ respective approaches in the context of the COVID-19 pandemic reflected their long-standing management models. Furthermore, we suggest that the insights gained from examining these approaches may provide a novel perspective on how to reimagine the current political economy.
Democracy & “Noxious” Markets
Authors: Satz Debra
Published: February 2023

How should a new political economy conceive of the role of markets in a just society? Markets clearly play an important role in efficiently allocating labor and goods, disseminating information, enabling cooperation among people who disagree with one another about how to live, and allowing individuals ‘ choices about where to direct their talents and resources. But acknowledging that markets play an important role does not mean that this role is simple or conforms to the status quo in capitalist countries like the United States. In this essay, I draw on classical and modern ideas to defend a limited role for markets that is tempered by democratic concerns.
In Search of Ontologies of Entanglement
Authors: Pendleton-Jullian Ann , Brown John Seely
Published: February 2023

We live in a world of entanglement, not enlightenment. We discuss why the two are not collapsible. Then, in search of concepts, methods, and sources for a frame of entanglement, we look at how an ontological turn in the social sciences helps us see the relationship between worldviews, values, and the complex practices of how societies enact their worlds, with an eye to those worldviews that assume, live, and enact entanglement. Finally, we offer some thoughts on moving beyond theory to action. Stimulated by the critical themes in Federica Carugati and Nathan Schneider's essay, and believing that “it matters what concepts we use to think concepts with,” we interrogate and expand on their themes to widen the conceptual aperture around the call for remaking our systems of governance.1
The 4th Palaeontological Virtual Congress
Authors: SÁNCHEZ-GARCÍA ALBA , RÍOS MARÍA , ARNAL FERNANDO ANTONIO MARTÍN , GAMONAL ARTURO , CRUZADO-CABALLERO PENÉLOPE , GONZÁLEZ-DIONIS JAVIER , VLACHOS EVANGELOS , GUERRERO-ARENAS ROSALÍA , CRESPO VICENTE D.
Published: February 2023

The emergence of new applications and technological advances has opened new and wider pathways for people to ensure effective science communication. This has become more significant after more than two years of difficulties and restrictions due to the COVID-19 epidemiological crisis, in which online platforms gained great relevance and proved key to keep up the drive for science communication (Barral, 2020). Aware of this, the first edition of the Palaeontological Virtual Congress (PVC) was organised in December 2018 by a team of young researchers from different nationalities. The purpose of that new congress format was simply to disseminate worldwide the most recent scientific advances in palaeontology in a fast, easy, inexpensive and inclusive way.
Revision of palaeoburmesebuthid scorpions in mid-Cretaceous amber from northern Myanmar (Scorpiones: Buthoidea)
Authors: XUAN QIANG , CAI CHEN-YANG , HUANG DI-YING
Published: February 2023

Nine new scorpion specimens belonging to the extinct family Palaeoburmesebuthidae are documented from mid-Cretaceous Burmese (Kachin) amber from northern Myanmar. More accurate morphological details, including lateral ocelli, dentition of chela finger, leg tarsal armature, trichobothrial pattern, and subaculear tuberance, are provided. Based on new morphological evidence, the diagnostic characters for Betaburmesebuthus are revised, and Spinoburmesebuthus is suggested as a junior synonym of Betaburmesebuthus syn. nov. Additionally, two new species of Betaburmesebuthus, B. villosus sp. nov. and B. fuscus sp. nov., are described from Burmese amber.
Zavrelia parapentatoma (Chironomidae: Diptera), a curious new species from North America, revealed by molecular methods
Authors: NAMAYANDEH ARMIN , HUDSON PATRICK L. , GHADERI EDRIS , STOTT WENDYLEE
Published: February 2023

In this study, we describe Zavrelia parapentatoma sp. nov. based on specimens collected near a cattail marsh in Michigan, USA. At first glance, the new species resembles Zavrelia pentatoma Kieffer & Bause, 1913 closely. However, a detailed morphological and molecular assessment revealed the differences. Morphologically the two species can be separated mainly based on the shape and pattern of long spinulae between long anal crests of adult males and setal patterns on the pupal abdomen. Larvae of both species also have some subtle morphological differences that are discussed in this study. Our molecular analysis of cytochrome oxidase (COI) genes and methods for delimiting species further supported the presence of a new species. In this study, we describe all the life stages, provide life history observations for this new species, and provide keys to adult males and immatures of the genus Zavrelia.
A new genus and species of Perlodinae (Plecoptera: Perlodidae) from Korea
Authors: MURÁNYI DÁVID , HWANG JEONG MI
Published: February 2023

Habaek koreanus gen. n., sp. n., a remarkable new Perlodinae is described from adults of both sexes, collected by Malaise traps in South Korea. On the basis of male characters, it is assigned to the tribe Perlodini, but its tribal classification needs to be clarified by characters of the larva and matured eggs. Affinities of the new genus are discussed, and a key is presented for the males of the Perlodini genera.
Decoupling the Conflicting Evaluative Meanings in Automatically Activated Race-Based Associations
Authors: Allidina Suraiya , Long Elizabeth U. , Baoween Wyle , Cunningham William A.
Published: February 2023

Implicit measures of attitudes have classically focused on the association between a social group and generalized valence, but debate exists surrounding how these associations arise and what they can tell us about beliefs and attitudes. Here, we suggest that representations of oppression, which relate positively to implicitly measured prejudice but negatively to explicitly measured prejudice, can serve to decrease the predictive validity of implicit measures through statistical suppression. We had participants complete a Black–White implicit association test (IAT) and an IAT measuring representations of oppression, and find that oppression-related representations statistically suppress the relation between IAT scores and explicit attitudes, such that accounting for these representations increases the total amount of variance explained by implicit measures. We discuss the implications of this work both for practical matters around use of the IAT and for theoretical debates on the conceptualization of valence in implicit attitudes.
Filter Questions in Symptom Assessment Affect the Prevalence of (A)Symptomatic COVID-19 Cases
Authors: Böhm Robert , Sprengholz Philipp , Betsch Cornelia , Partheymüller Julia
Published: February 2023

Background

It has been reported that a substantial number of COVID-19 infections are asymptomatic, with both symptomatic and asymptomatic infections contributing to transmission dynamics. Yet, the share of asymptomatic cases varies greatly across studies. One reason for this could be the measurement of symptoms in medical studies and surveys.

Design

In 2 experimental survey studies (total N > 3,000) with participants from Germany and the United Kingdom, respectively, we varied the inclusion of a filter question on whether participants who tested positive for COVID-19 had experienced symptoms prior to presenting a checklist of symptoms. We measured the reporting of asymptomatic (versus symptomatic) COVID-19 infections.

Results

The inclusion of a filter question increased the reporting of asymptomatic (versus symptomatic) COVID-19 infections. Particularly mild symptoms were underreported when using a filter question.

Conclusions and implications

Filter questions affect the reporting of (a)symptomatic COVID-19 cases. To account for such differences in the estimation of population infection rates, future studies should transparently report the applied question format.

Highlights

Both symptomatic and asymptomatic infections are important for COVID-19 transmission dynamics. In previous research, symptoms have been assessed either with or without a filter question prior to presenting a symptom list. We show that filter questions reduce the reporting of asymptomatic infections. Particularly mild symptoms are underreported when using a filter question.
Specters of Minks: Postcapitalist Elegies and Multispecies Solidarities
Authors: Leep Matthew
Published: February 2023

While narrative approaches in International Relations (IR) have become increasingly prominent, posthumanist narratives of capitalism remain on the margins. Informed by feminist avant-garde poet Susan Howe and philosopher Jacques Derrida, I develop a ‘drift narrative’ approach to human-mink relations during the SARS-CoV-2 pandemic, wherein millions of minks in fur farms were infected by the coronavirus and culled. This approach employs the use of postcapitalist elegies constructed in a wildlife refuge located near a mink factory farm. In a context of global mink culls, the wildlife refuge – where minks live freely – proximate to a local industrial mink fur farm – where minks are caged and killed for profit – became the site of (re)writing IR in drift narrative form. This poetic analysis highlights trans-spatial links of animal capital and employs intermixed elegiac images, sound recordings, and textual fragments to help us become attuned to nonhuman dreams, desires, losses, and futures. Grounding persistence for postcapitalist futures within the dreams of the dead, the drift narrative generates a spectral form of global multispecies solidarity. Contributing to the interspecies and narrative turns in IR, as well as multidisciplinary work on multispecies solidarity, the drift narrative offers an aesthetic and ethical critique of past and future animal capital systems that render more-than-human life as killable.
Examining the Awareness Levels of Parents on Child Sexual Abuse
Authors: Berkmen Bengü
Published: February 2023

Introduction:

Child sexual abuse (CSA) is defined as all kinds of actions that an adult uses a child for sexual purposes. The studies concluded that parents have incomplete or incorrect information and the protection of children against abuse is the fundamental duty of parents. This study analyses the CSA awareness levels of parents.

Methods:

Descriptive survey model is performed. The research sample covers 455 parents. The Child Sexual Abuse Awareness Scale for Parents and a demographical information form was used for research data collection and analyzed on SPSS 21.0 software.

Results:

A statistically significant difference was found between parents’ CSA awareness levels and age, gender, marital status, duration of marriage, education level, and number of children. The results showed that parents who were married for up to 10 years had a university degree, had only 1 child, and had higher awareness of sexual abuse myths. Contrary to expectations, no significant results were obtained regarding the signs of sexual abuse scores of groups with high awareness of myths of sexual abuse.

Implications for Research and Practice:

Contrary to the literature, the awareness levels of fathers about CSA are lower than the awareness levels of mothers, and the awareness levels of parents decrease as they get older. There is a need for further comprehensive and more scientific studies to identify the CSA problem in North Cyprus and propose solutions, and consequently prevention programs should be developed for professional groups that are related with child and parents.
“Stuck in a Loop”: A Qualitative Examination of Challenges for Children and Adolescents With Attention-Deficit/Hyperactivity Disorder and Anxiety
Authors: Jackson Anna , Mulraney Melissa , Melvin Glenn A. , Evans Subhadra , Efron Daryl , Sciberras Emma
Published: February 2023

Children and adolescents (henceforth “children”) with both attention-deficit/hyperactivity disorder (ADHD) and anxiety experience greater difficulties than children with either alone, though qualitative methodologies are yet to be used to understand the challenges this population experiences. We aimed to explore parent-reported daily impacts of co-occurring anxiety in children with ADHD (ages 8–13 years). Participants were enrolled in an Australian trial evaluating an adapted anxiety intervention and were eligible if their child met diagnostic criteria for ADHD plus separation, social, and/or generalized anxiety disorder. A baseline measure of life impacts associated with child anxiety captured situations parents reported were difficult, due to their child’s anxiety. Reflexive thematic analysis of free-text responses ( N = 203) facilitated new insights via inductively generating key themes. Three overarching themes highlighted (1) child difficulties with everyday situations and processes due to their anxiety; (2) the nature of the child’s anxiety being pervasive and unrelenting; and (3) the strain placed on the child’s family system. This study enhances understanding of daily impacts associated with co-occurring anxiety and ADHD and may contribute to an improved understanding of support needs. Results reiterate the need to identify co-occurring difficulties in children with ADHD and support both children and their families.
Dedifferentiated Ovarian Carcinoma with ARID1A and ARID1B Mutations: A Clinicopathological Report and Literature Review
Authors: Kamal Maria , Atwi Doaa , Pang Hui , Li Shibo , Hassell Lewis
Published: February 2023

Dedifferentiated carcinoma of the female genital tract is a relatively recently recognized aggressive tumor affecting predominantly perimenopausal and postmenopausal women. In addition to having an undifferentiated component, dedifferentiated carcinoma includes a juxtaposed endometrioid adenocarcinoma, FIGO grade 1 or 2. Molecular characterization of these tumors has been a subject of discussion in multiple recent articles. We present a case of dedifferentiated carcinoma of the ovary in a 70-year-old female demonstrating concurrent inactivation of ARID1A and ARID1B. To the best of our knowledge, this is the second clinical report demonstrating dedifferentiated carcinoma of the ovary with concurrent inactivation of ARID1A and ARID1B. ARID1A and ARID1B inactivation seems to represent an alternate mechanism of switch/sucrose nonfermentable complex inactivation in the development of dedifferentiated carcinoma. Additional studies are warranted to precisely understand the molecular mechanism of cellular dedifferentiation in the dedifferentiated endometrial/ovarian carcinomas, thus guiding the development of targeted therapy.
Complications after removal of totally implanted central venous access devices: A single-center retrospective study
Authors: Gennequin Mael , Elmawieh Jamie , Gomas Frederic
Published: February 2023

Background:

Complications after removal of totally implanted vascular access devices. (TIVADs) have not been studied widely. The aim of this study was to assess the prevalence and risk factors of these complications.

Methods:

This was a single-center retrospective study conducted in Gustave Roussy hospital in Villejuif, Ile-de-France, France. All adult patients scheduled for TIVAD removal between January 2015 and November 2019 were eligible for the study. The record of complications was compiled by noting the reason for a surgical or emergency department consultation during the month following removal, and also by calling the patients during the week of TIVAD removal to assess whether surgical advice was needed.

Results:

There were 2533 included patients, representing 2583 TIVAD removals. The prevalence of complications was 1.47% ( n = 38), of which 0.31% were infectious complications ( n = 8). These complications required surgical or interventional radiology management in 50% of cases. In multivariate analysis, two independent risk factors were associated with these complications: the duration of the surgical procedure ( p = 0.04) and the active status of the underlying malignant disease ( p = 0.07).

Conclusions:

Complications after TIVAD removal are uncommon (prevalence = 1.47%), but their morbidity appears to be high, with interventional procedures frequently needed. The duration of the removal procedure and the active status of cancer appear to be associated with the occurrence of complications.
Concurrent Dengue-Malaria Infection: The Importance of Acute Febrile Illness in Endemic Zones
Authors: González-Macea Orlando , Martínez-Ávila María Cristina , Pérez Marien , Tibocha Gordon Ingrid , Arroyo Salgado Bárbara
Published: February 2023

Context:

Acute febrile disease (AFI) in endemic tropical areas is a frequent reason for consulting the emergency services. Infection by 2 or more etiological agents may modify clinical and laboratory parameters, making diagnosis and treatment a challenge.

Case report:

We report the case of a patient who came from Africa and consults in Colombia, with AFI with thrombocytopenia that was eventually diagnosed to have concurrent infection with Plasmodium falciparum malaria and dengue.

Conclusions:

Dengue-malaria coinfection infection reports are scarce; it should be suspected in patients living or returning from areas where both diseases are endemic or during dengue outbreaks. This case serves as a reminder of this important condition that causes high morbidity and mortality if it is not early diagnosed and treated.
Apex-shifted Radon transform for baseline-subtraction-free (BSF) damage scattered wave extraction
Authors: Loshelder Augustine E , He Jiaze , Aktharuzzaman Md , Harb Mohammad S , Rao Jing
Published: February 2023

In ultrasonic structural health monitoring (SHM) and nondestructive evaluation (NDE), the scattered waves caused by damage sites and defects are the key to damage diagnosis. However, structural components and boundaries also interact with traveling waves, creating events that can bury damage scattered waves. The baseline subtraction method, which directly subtracts the waveform of a damage signal from that of a pristine baseline signal, is a common processing technique to separate these damage scattered waves. However, baseline subtraction is less effective when a component is measured in different environmental/loading conditions from when its baseline was recorded. For instance, baseline subtraction can be ineffective in aerospace structural parts because such parts expect significant and routine changes in ambient temperature, pressure, and humidity. To overcome the limitations of baseline subtraction, this paper proposes to develop an spex-shifted Radon transform (ASRT)-based damage scattered event extraction technique without baseline subtraction. Our proposed ASRT method converts the original time-space [Formula: see text] domain signals to a time delay–curvature–apex offset [Formula: see text] domain, which targets specific geometries of scattered/reflected waves in the [Formula: see text] domain and compresses them into a single point-like region in the new domain. In this domain, identifying and isolating targeted events becomes significantly easier. To benchmark the performance of this baseline-subtraction-free (BSF) method, ASRT is applied for signals acquired from (1) spectral finite element-based simulations to scan a water-immersed steel specimen (2) 3-D wave simulations in a bent aluminum plate, and (3) a full matrix capture for experimentally scanning a high-density polyethylene (HDPE) with multiple holes. The goal in each case is to target and separate events of interest from the original signals using the proposed algorithm. The results suggest the ASRT method is effective as a damage scattered wave extraction tool for ultrasonic SHM and NDE.
Postpartum people’s experiences of and responses to the COVID-19 pandemic during the first year of the pandemic: A descriptive qualitative study
Authors: Bayrampour Hamideh , Tsui Ming Yee Emily
Published: February 2023

Background:

Most evidence on the impact of pandemic on perinatal population’s experiences has reported such effects in a portion of the pandemic.

Objectives:

The aim of this study was to understand the postpartum people’s experiences of and responses to the coronavirus disease 2019 pandemic during the first year and to identify their health care needs.

Design:

This is a descriptive qualitative study.

Methods:

This study was conducted in British Columbia, Canada, between March 2020 and April 2021. Participants (N = 268) were at 4 months postpartum and were recruited as part of the Pregnancy Specific Anxiety Tool study through prenatal care clinics and classes, community laboratory services and social media. Qualitative data were obtained using six online open-ended questions and were analysed using thematic analysis.

Results:

Findings were grouped under five central themes: protecting baby (with three categories including hypervigilance, constant decision-making to find balance and developmental issues); psychological adjustments (with three categories including coping, anxiety and grief); experience of isolation and lack/loss of support (with two categories including isolation and loss of expected support); unexpected interruptions and life events (with four categories including interrupted maternity leave, unexpected changes/life events, positive impacts and interruption in health care services); and perceived postpartum care needs (with five categories including in-person visits, allowing support persons, providing information/education/support groups, mental health and social support and pro-active check-ins).

Conclusion:

Several impacts of the pandemic persisted throughout the first year, particularly isolation and lack of support. These findings can inform responsive health care services to address the emerging needs of postpartum people throughout the pandemic.
B Lineage Cells and IgE in Allergic Rhinitis and CRSwNP and the Role of Omalizumab Treatment
Authors: Bai Junqin , Tan Bruce K.
Published: February 2023

Background

Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are two prevalent nasal diseases where both type 2 inflammation and immunoglobulin E (IgE) may play important roles. Although they can exist independently or comorbidly, subtle but important differences exist in immunopathogenesis.

Objective

To summarize current knowledge of pathophysiological roles of B lineage cells and IgE in AR and CRS with nasal polyps (CRSwNP).

Methods

Searched PubMed database, reviewed AR and CRSwNP-related literature, and discussed disease diagnosis, comorbidity, epidemiology, pathophysiology, and treatment. Similarities and differences in B-cell biology and IgE are compared in the 2 conditions.

Results

Both AR and CRSwNP have evidence for pathological type 2 inflammation, B-cell activation and differentiation, and IgE production. However, distinctions exist in the clinical and serological profiles at diagnosis, as well as treatments utilized. B-cell activation in AR may more frequently be regulated in the germinal center of lymphoid follicles, whereas CRSwNP may occur via extrafollicular pathways although controversies remain in these initial activating events. Oligoclonal and antigen-specific IgE maybe predominate in AR, but polyclonal and antigen-nonspecific IgE may predominate in CRSwNP. Omalizumab has been shown efficacious in treating both AR and CRSwNP in multiple clinical trials but is the only Food and Drug Administration-approved anti-IgE biologic to treat CRSwNP or allergic asthma. Staphylococcus aureus frequently colonizes the nasal airway and has the ability to activate type two responses including B-cell responses although the extent to which it modulates AR and CRSwNP disease severity is being investigated.

Conclusion

This review highlights current knowledge of the roles of B cells and IgE in the pathogenesis of AR and CRSwNP and a small comparison between the 2 diseases. More systemic studies should be done to elevate the understanding of these diseases and their treatment.
“It’s Your Finsta at the End of the Day . . . Kind of”: Understanding Emerging Adults’ Self-Presentational Changes on Secondary Accounts
Authors: Tao Michelle , Ellison Nicole B.
Published: February 2023

This study explores emerging adults’ reflections about how their secondary Instagram account (“Finsta” or Fake Instagram) self-presentation evolved over time, from account creation to their present use. Drawing on interview data collected from female emerging adults ( N = 17) who had at least one Finsta and one Rinsta (i.e., Real Instagram), we use Emerging Adulthood as a frame for understanding how their content-sharing practices changed, reflecting their own development from adolescence to adulthood. Our participants described how their Instagram content-sharing behaviors evolved, reflecting their desire to be seen as more mature, especially in regard to managing negative self-presentational content. Furthermore, some participants described the difficulties introduced by context collapse associated with presenting to two distinct networks, both high school and college followers. Finally, and reflecting contemporary developments, we document how the “Making Rinsta Casual Again” trend and the COVID-19 pandemic influence users’ self-presentational behaviors on image-based social media platforms like Instagram.
Recalling the Past Within a Social Network’s Collective Memory Work: How Did Korean Twitter Users Shape #Equal_Punishment_for_Equal _Crime From Their Experiences?
Authors: Kang Hyewon , Kim Hae Won , Baek Giyeon , Park Dongsook
Published: February 2023

On 19 May 2018, more than 12,000 women gathered at Hyehwa subway station in Seoul, South Korea to protest discrimination against Korean women and spy camera involved crimes. This rally was a response to an incident in which a male nude model in a class was secretly photographed by a female model at Hongik University. This study examined how discourses on Twitter regarding the incident led to the demonstration and what was the memory working that shaped significant discourses through critical discourse analysis. First, a discourse that “women have long been victims” emerged through personal remembrances. Second, photographs of the female suspect standing with police officers directed a discourse that “women have been treated unfairly by public authorities” through collective witnessing. Third, many women contextualized the incident as a gendered event by connecting the past feminist movements. Finally, through appropriating past slogans and accumulated hashtags on Twitter, the main slogan of the rally #Equal_punishment_for_equal_crime was established. This study provides an under-researched context of digital mnemonic practices and the logic of connective actions by analyzing feminist movements in South Korea.
Accuracy of stress perfusion cardiac magnetic resonance imaging in a district hospital
Authors: Gleditsch Jostein , Halvorsen Bjørn A , Bratis Konstantinos , Alvim Astrid D , Jordal Anders , Fjeld Jan G , Raouf Nezar , Aslam Sohail , Nagel Eike , Hall Christian
Published: February 2023

Background

The European Society of Cardiology has published updated guidelines regarding pathways for diagnosis and management of obstructive coronary artery disease (CAD). Non-invasive functional assessment, for example, by stress perfusion cardiac magnetic resonance (stress pCMR) is recommended in patients with intermediate pretest probability of disease. Previous pCMR studies were mainly performed in high volume university hospitals with experienced radiologists or cardiologists interpreting the images.

Purpose

The aim of the present study was to evaluate the feasibility of establishing a stress pCMR imaging service in a district hospital.

Material and Methods

One hundred and thirteen patients with intermediate pretest probability of CAD referred for single-photon emission computed tomography (SPECT) at the regional hospital also underwent adenosine stress pCMR locally. The diagnostic analysis was compared to that of an experienced cardiac magnetic resonance (CMR) center serving as a reference.

Results

Inter-rater agreement between local readers and the reference reader was substantial to perfect for late gadolinium enhancement (LGE) (weighted kappa = 0.76 and 0.82), but only fair to moderate for pCMR ( k = 0.34 and 0.51). No improvement in agreement between reference reader and local reader during the study was demonstrated.

Conclusion

CMR is feasible in patients with intermediate pretest probability of obstructive CAD in the setting of a district hospital. However, as opposed to infarct detection with LGE, the interpretation of stress pCMR was more challenging. To establish this method, we suggest obtaining experience in close collaboration with a reference CMR center.
Implementation of Virtual Fontan Heart Camps During a Pandemic
Authors: Tham Edythe B , Harake Danielle E , Lin Lily Q , Du Katie J , Harris Lucy E , Williams Elina , Ash Alanna L , Escudero Carolina A
Published: February 2023

Background

Children with a Fontan operation represent a unique form of congenital heart disease (CHD) that requires multiple cardiac surgeries and procedures with an uncertain long-term outcome. Given the rarity of the types of CHD that require this procedure, many children with a Fontan do not know any others like them.

Methods

With the cancelation of medically supervised heart camps due to the COVID-19 pandemic, we have organized several physician-led virtual day camps for children with a Fontan operation to connect with others in their province and across Canada. The aim of this study was to describe the implementation and evaluation of these camps via the use of an anonymous online survey immediately after the event and reminders on days 2 and 4 postevent.

Results

Fifty-one children have participated in at least 1 of our camps. Registration data showed that 70% of participants did not know anyone else with a Fontan. Postcamp evaluations showed that 86% to 94% learned something new about their heart and 95% to 100% felt more connected to other children like them.

Conclusion

We have demonstrated the implementation of a virtual heart camp to expand the support network for children with a Fontan. These experiences may help to promote healthy psychosocial adjustments through inclusion and relatedness.
Arm Function After Arthroscopic Decompression of the Suprascapular Nerve at the Spinoglenoid Notch and Suprascapular Notch in Volleyball Players
Authors: Brzoska Roman , Laprus Hubert , Klaptocz Patryk , Malik Shahbaz S. , Solecki Wojciech , Blasiak Adrian
Published: February 2023

Background:

Suprascapular nerve (SSN) entrapment in volleyball players leads to infraspinatus (ISP) muscle atrophy and weakness of abduction and external rotation (ER) of the shoulder.

Purpose:

To assess functional outcome after arthroscopic extended decompression of SSN in the spinoglenoid notch and suprascapular notch in a group of volleyball athletes.

Study Design:

Case series; Level of evidence, 4.

Methods:

Volleyballers who underwent arthroscopic SSN decompression were analyzed retrospectively. Assessment tools consisted of range of motion and ER strength on Lovett scale and postoperative ER strength measured by dynamometer, Constant-Murley score (CMS), and visual evaluation of ISP muscle recovery by assessing muscle bulk.

Results:

The study included 10 patients (9 male and 1 female). The mean age was 25.9 years (range, 19-33) and mean follow-up was 77.9 months (range, 7-123). The mean range of postoperative ER at 90° of abduction (ER2) was 105.6° (88°-126°) and 108.5° (93°-124°) for the contralateral side, while ER2 strength was 8 ± 2.6 and 12.65 ± 2.8 kg ( P < .01) respectively. Mean CMS was 89.9 (84-100). In 5 cases, there was complete recovery of ISP muscle atrophy whereas 2 patients had partial recovery and 3 had none.

Conclusion:

Arthroscopic SSN decompression in volleyball players improves shoulder function, but results of ISP recovery and ER strength are variable.
Prevalence and Risk Factors of Internet Gaming Disorder Under the COVID-19 Pandemic Among University Students in Macao
Authors: Wang Yan , Liu Ming , Nogueira Oi Ching Bernice Lam
Published: February 2023

Introduction

During the COVID-19 pandemic, the zero-tolerance policy implemented in Macao affected university students’ life and learning styles.

Objectives

This study aimed to investigate the prevalence of internet gaming disorder (IGD) and analyze its risk factors among university students of Macao amid the COVID-19 pandemic.

Methods

Two hundred and twenty-nine university students were recruited by convenience sampling. The cross-sectional investigation was conducted using the 9-item Chinese version of the IGD Scale, the Chinese Version of the Self-Compassion Scale, and the Chinese version of the Brief Resilience Scale.

Results

The prevalence was 7.4%. Compared to Non-IGD gamers, the IGD gamers were more likely to be the older, male gender, with a longer gaming history, with more game hours per day in the last month, and with a lower self-compassion score and resilience.

Conclusion

The prevalence of IGD increased. Students who are the older, male gender, with more gaming time, low self-compassion, and low resilience, have a high possibility of IGD.
SECTM1-based CAR T cells enriched with CD7-low/negative subsets exhibit efficacy in CD7-positive malignancies
Authors: Wei Wenwen , Ma Haiyan , Yang Dong , Sun Bin , Tang Jie , Zhu Yongjie , Chen Xinchuan , Huang Xiaoou , Liu Jiazhuo , Hu Zhengfei , Liu Ting , Zou Liqun , Zhao Xudong
Published: February 2023

CD7 has been found to be a promising chimeric antigen receptor (CAR) T cell target in several clinical trials. However, its expression on normal T cells poses additional challenges in CD7-directed CAR therapy, such as complete fratricide, contamination with malignant cells, and immune suppression due to T-cell aplasia. By taking advantage of evolved affinity between ligand and receptor, we constructed a CD7-directed CAR with the extracellular domain of SECTM1, a natural ligand of CD7, as the recognition domain. SECTM1 CAR T cells killed the majority of T cells with high CD7 expression in vitro. However, SECTM1 CAR T cells with low or negative CD7 expression survived, expanded, and showed strong cytotoxicity to CD7+ malignant cell lines and primary leukemic blasts from patients with T-cell acute lymphoblastic leukemia and acute myelogenous leukemia in vitro. It also exhibited efficacy in inhibiting xenograft tumor growth in vivo. More exploration is needed for clinical efficacy potential to patients with CD7+ malignancies.
Multi-Objective Optimization of Fused Deposition Modeling for Mechanical Properties of Biopolymer Parts Using the Grey-Taguchi Method
Authors: Kumar Kapil , Singh Hari
Published: February 2023

The urgent need to develop customized functional products only possible by 3D printing had realized when faced with the unavailability of medical devices like surgical instruments during the coronavirus-19 disease and the on-demand necessity to perform surgery during space missions. Biopolymers have recently been the most appropriate option for fabricating surgical instruments via 3D printing in terms of cheaper and faster processing. Among all 3D printing techniques, fused deposition modelling (FDM) is a low-cost and more rapid printing technique. This article proposes the fabrication of surgical instruments, namely, forceps and hemostat using the fused deposition modeling (FDM) process. Excellent mechanical properties are the only indicator to judge the quality of the functional parts. The mechanical properties of FDM-processed parts depend on various process parameters. These parameters are layer height, infill pattern, top/bottom pattern, number of top/bottom layers, infill density, flow, number of shells, printing temperature, build plate temperature, printing speed, and fan speed. Tensile strength and modulus of elasticity are chosen as evaluation indexes to ascertain the mechanical properties of polylactic acid (PLA) parts printed by FDM. The experiments have performed through Taguchi's L27 orthogonal array (OA). Variance analysis (ANOVA) ascertains the significance of the process parameters and their percent contributions to the evaluation indexes. Finally, as a multi-objective optimization technique, grey relational analysis (GRA) obtains an optimal set of FDM process parameters to fabricate the best parts with comprehensive mechanical properties. Scanning electron microscopy (SEM) examines the types of defects and strong bonding between rasters. The proposed research ensures the successful fabrication of functional surgical tools with substantial ultimate tensile strength (42.6 MPa) and modulus of elasticity (3274 MPa).
Factors associated with diabetes-related distress among Asian patients with poorly controlled type-2 diabetes mellitus: a cross-sectional study in primary care
Authors: Guo Xiaoxuan , Wong Pang Nee Frida , Koh Yi Ling Eileen , Tan Ngiap Chuan
Published: February 2023

Background

Diabetes-related distress (DRD) is a negative emotional state related to the burden of living with diabetes mellitus. It has been associated with poor self-care and glycaemic control. This cross-sectional study aimed to examine the factors associated with DRD among urban Asian patients with poorly controlled type-2 diabetes mellitus (T2DM) in primary care in Singapore. The factors included demographics, diabetes history, medical co-morbidities, mood disorders and social history.

Methods

Patients with T2DM and HbA1c of 8% or more were recruited from 2 public primary care centres in Singapore. They were administered a questionnaire survey to identify DRD based on the Problem Area In Diabetes (PAID) scale. Their anxiety and depression were screened using GAD-7 and PHQ-9, and quality of life (QOL) measured using the EQ-5D-5L. Their clinical data, including HbA1c, comorbidities and medications, were extracted from the electronic medical records.

Results

Among the 356 subjects, the prevalence of DRD was 17.4%. DRD was significantly associated with younger age (AOR (95% CI) = 0.93 (0.89–0.97),p = 0.001), ex-smoker status (AOR (95% CI) = 22.30 (2.43–204.71),p = 0.006) and history of kidney disease (AOR (95% CI) = 3.41 (1.39–8.35),p = 0.007). Those who screened positive for depression (AOR (95% CI) = 4.98 (1.19–20.86),p = 0.028) were almost five times more likely to have DRD. Quality of life was lower among those with DRD (EQ5D index score AOR (95% CI) = 0.11 (0.01–0.97),p = 0.047), who also tended to feel that diabetes pharmacotherapy interfered with their normal life (AOR (95% CI) = 2.89 (1.38–6.08),p = 0.005).

Conclusion

About 1 in 6 patients with poorly controlled T2DM had DRD. Younger age, ex-smoker status, history of kidney disease, and those with depressive symptoms were most at risk.
Multinomial logistic regression analysis of the determinants of anaemia severity among children aged 6–59 months in Ghana: new evidence from the 2019 Malaria Indicator Survey
Authors: Klu Desmond , Atiglo Donatus Yaw , Christian Aaron Kobina
Published: February 2023

Background

Anaemia among children under age five is a major public health issue. Although anaemia prevalence is declining in Ghana, the severity among anaemic children is worsening. This study aims to investigate the determinants of anaemia severity among children aged 6 to 59 months in Ghana.

Method

The study utilized a weighted sample of 1,258 children with anaemia with data obtained from the 2019 Ghana Malaria Indicator Survey. The predictor variables included maternal, household child and health system characteristics. SPSS version. At the multivariate level, three different multinomial logistic models were run with selected predictor variables. All tests were conducted at the 95% confidence level.

Results

The overall anaemia prevalence among children under age five was 43.5%. Of these, 2.6% were severely anaemic, 48.5% were moderately anaemic, and 48.9% had mild anaemia. The multinomial analysis showed that maternal, household, child and health system factors significantly predicted anaemia levels among anaemic children. The results indicate that a lower likelihood of anaemia severity is likely to be found among children whose mothers belong to Pentecostal/Charismatic faith (AOR = 0.18-model I; AOR = 0.15-model III) and children who tested negative for malaria (AOR = 0.28-model II and III). Again, a higher probability of anaemia severity was found among anaemic children whose mothers were not aware of NHIS coverage of malaria (AOR = 2.41-model II, AOR = 2.60-model III). With regard to moderate anaemia level, children who belong to the poorest, poorer and middle household wealth index had a higher likelihood of being moderately anaemic compared to those in rich households. Similarly, anaemic children who were less than 12 months old (AOR = 2.21-model II, AOR = 2.29-model III) and those between the ages of 1–2 years (AOR = 1.84-model II, AOR = 1.83-model III) were more likely to have moderate anaemia levels.

Conclusion

The study findings show the importance of understanding the interrelation among different factors that influence anaemia severity among children under age five as critical in developing strategies and programmes aimed at addressing childhood anaemia.
Association of HTR3B gene polymorphisms with depression and its executive dysfunction: a case–control study
Authors: Wang Lina , Wang Miao , Zhao Chaoben , Jian Jia , Qiao Dongdong
Published: February 2023

Background

Previous studies have shown that depression was associated with HTR3B gene. The aim of this study was to investigate the relationship between polymorphisms of the HTR3B gene and depression and its executive dysfunction in Chinese Han population.

Methods

A total of 229 patients with depressive disorder and 202 healthy controls were enrolled. Six Single nucleotide polymorphism sites (SNPs) including rs10789970, rs4938056, rs12421126, rs1176744, rs2276305 and rs12795805 were genotyped by Snapshot. Clinical features were collected using a general demographic questionnaire. The 24-item Hamilton Depression Scale (HAMD) was used to assess the symptoms’ severity of the patients. The patients' executive function was assessed using a series of cognitive tests including Maze Test, Symbolic Coding Test, Spatial Span Inverse Order Test, Linking Test, and Emotional Management Test.

Results

The genotypic and allelic distributions of rs1176744 in HTR3B gene were significantly different (χ2 = 11.129, P = 0.004, χ2 = 9.288, P = 0.002, respectively) between patients and controls. The A allele was positively correlated with depression. The proportion of A carriers was significantly higher and that of C carriers was lower in patients than those in controls. Patients had significantly lower scores of Spatial Span Inverse Order Test in carriers of A allele at locus rs1176744 and higher scores in carriers of C alleles at locus rs1176744 and rs12795805.

Conclusions

The polymorphisms of HTR3B gene may be associated with depression in Chinese Han population. The A allele of rs1176744 may increase the risk of developing depression and executive dysfunction while C alleles of rs1176744 and rs12795805 may be the protective factors for executive dysfunction in patients with depression.
Tele-pharmacy perception, knowledge and associated factors among pharmacy students in northwest Ethiopia: an input for implementers
Authors: Tegegne Masresha Derese , Wubante Sisay Maru , Melaku Mequannent Sharew , Mengiste Nebyu Demeke , Fentahun Ashenafi , Zemene Wondwossen , Zeleke Tirualem , Walle Agmasie Damtew , Lakew Getnet Tadesse , Tareke Yonas Tsegaw , Abdi Mubarek Suleman , Alemayehu Hawariyat Mamuye , Girma Eskedar Menkir , Tilahun Gizaw Getye , Demsash Addisalem Workie , Dessie Hiwote Simane
Published: February 2023

Abstracts

Background

Tele-pharmacy is a subset of telemedicine in which pharmacies use telecommunication technology to provide patient care. Tele-pharmacy can improve pharmaceutical care service delivery by reducing medication errors, improving access to health professionals and facilities in remote and rural areas, and minimizing adverse drug events. However, there is limited evidence regarding future pharmacists' knowledge and perceptions of the Tele-pharmacy system in Ethiopia. As a result, this study aimed to assess tele-Pharmacy perception, knowledge and associated factors among pharmacy students in Northwest Ethiopia.

Methods

An institutional-based cross-sectional study was conducted among 376 pharmacy students in Northwest Ethiopia between July 15 and August 27, 2022. A pre-tested self-administered questionnaire was used to collect data. The data were entered using Epi info version 7.0 and analyzed using SPSS version 25. Descriptive statistics, bivariable and multivariable logistic regression analysis were used to describe pharmacy students' knowledge and perceptions of Tele-pharmacy and identify associated factors. An adjusted odds ratio (OR) and a p-value with a 95% confidence interval (CI) were calculated to declare statistical significance.

Results

From a total of 352 participants, about 32.4% with [95% CI (27%-37%)] and 48.6% with [95% CI (43%—54%)] had good knowledge and a positive perception toward Tele-pharmacy, respectively. Being age group of 26–30 (AOR = 0.35, 95% CI: 0.17–0.68), being male (AOR = 2.38, 95% CI: 1.26–4.49), Having a CPGA of > 3.5 (AOR = 2.28, 95% CI: 1.24–4.19), Taking basic computer training (AOR = 2.00, 95% CI: 1.17–3.39), Management support (AOR = 1.84, 95% CI: 1.06–3.19) were found to be significantly associated with pharmacy students' knowledge of Tele-pharmacy. Similarly, having access to electronic devices (AOR = 3.80, 95% CI: 1.81–7.97), training related to pharmacy information systems (AOR = 6.66, 95% CI: 3.34–13.29), availability of guidelines (AOR = 2.99, 95% CI: 1.62–5.50) were found to be significantly associated with pharmacy students' perceptions of Tele-pharmacy.

Conclusion

This study found that pharmacy students have limited knowledge and perceptions of the Tele-pharmacy system. A continuing Tele-pharmacy training package, incorporating pharmacy information system guidelines as part of their education, and providing managerial support could be recommended to improve pharmacy students' knowledge and perception of Tele-pharmacy.