bluuebunny/crossref_metadata_2025 huggingface dataset:
PROTEIN ENGINEERING OF BST POLYMERASE FOR ISOTHERMAL
AMPLIFIСATION PURPOSES
Authors: Cherkashina Anna S. , Mikheeva Olga O. , Akimkin Vasiliy G.
Published: February 2024

The review is devoted to protein engineering of Bst polymerase using various
methods. To modify the enzyme, approaches such as the production of chimeric proteins,
directed evolution, directed and random mutagenesis have been used. Examples of
successful changes in enzyme properties such as catalytic activity, processivity, thermal
stability, and resistance to inhibitors are described.
ADAPTIVE DLC COATINGS WITH DIFFERENT MoS2 CONTENT
Authors: Osada Piotr , Kot Marcin , Zimowski Sławomir , Wiązania Grzegorz , Lackner Jürgen
Published: February 2024

DLC coatings are widely used in engineering as they are resistant to abrasive wear. However, they exhibit anincreased coefficient of friction at temperatures of around 300C. Soft MoS2 coatings are known to maintaina low coefficient of friction at temperatures up to about 350C, but suffer from relatively high abrasive wear.Publications from the last decade report a synergistic improvement in the tribological performance of acoating consisting of both these materials. The aim of this study was to investigate the wear resistance ofcoatings composed of different a-C and MoS2 contents applied by magnetron sputtering on steel. The resultsobtained in tribological tests conducted using the ball-and-disk method showed at least 20% better adhesionto the substrate of the two-component nanocomposite coating and its increased wear resistance from 15% toas much as 700%, compared to single-component coatings in tests conducted at 20C and 250C. The testsshowed no deterioration of the two-component coating's coefficient value compared to DLC.
Factores de riesgo y reacciones adversas postransfusionales en pacientes hospitalizados en una institución privada de la ciudad de Guayaquil en el año 2022
Authors: Mendoza-Castro Sharon Natasha , Castro-Jalca Jazmín
Published: February 2024

La medicina transfusional tiene un gran impacto en la salud a nivel mundial, motivo de que es una opción terapéutica para pacientes que poseen una carencia de componentes sanguíneos, aproximadamente del 1-3% de los eventos transfusionales están asociados a reacciones adversas postransfusionales. El objetivo de la investigación fue determinar las reacciones adversas postransfusionales y sus factores de riesgo en pacientes hospitalizados en una Institución privada en la ciudad de Guayaquil. Su metodología fue estudio transversal retrospectivo, cuya población corresponde a 580 pacientes hospitalizados en el Hospital Luis Vernaza de la Junta de Beneficencia de Guayaquil que fueron transfundidos en el año 2022. Las variables que presentaron asociación son la politransfusión, el factor Rh, y el peso. Se encontraron 8 reacciones agudas de origen inmunológico/inmediatas, de ellas 6 alérgicas inmediatas, 2 reacciones febril no hemolítica, además de 1 reacción adversa no inmunológica/tardía como la reacción alérgica tardía. No se encontró significancia estadística entre las reacciones adversas postransfusionales y los factores de riesgo. En conclusión, existe un mínimo de reacciones adversas postransfusionales, sin embargo, se sugiere se conozca las causas o factores de riesgos que lo provocaron, así como también registrar las reacciones adversas existentes en formularios establecidos.
The relationship between postprandial C peptide-glucose ratio, beta-cell function and treatment success in type 2 diabetes mellitus
Authors: Kocanoğlu Abdülkadir , Oral Alihan , Vural Keskinler Miraç , Sadeçolak Mustafa , Oğuz Aytekin
Published: February 2024

Objectives: This study aims to investigate the relationship between postprandial C-peptide-to-glucose ratio (PCGR), β-cell function and successful glycemic glycemic control in type 2 diabetes mellitus (DM) and determine the efficacy and feasibility of the PCGR index in the individualization of diabetes treatment.

Materials and methods: This prospective study included a total of 49 patients (17 males, 32 females; mean age: 56±10 years; range, 32 to 75 years) under follow-up in Istanbul Medeniyet University Göztepe Training and Research Hospital Department of Internal Medicine with the diagnosis of type 2 DM between June and December 2016. Patients receiving insulin or insulin secretagogues were excluded. Data including age, sex, weight, height, waist circumference, hip circumference, date of DM diagnosis, serum hemoglobin A1c (HbA1c), and creatinine levels were recorded. All patients underwent a mixed meal test and their fasting blood glucose, C-peptide, postprandial glucose, and C-peptide levels were measured and recorded. Patients with a serum HbA1c level of 7% or lower were considered to have good glycemic control while patients with a serum HbA1c level of higher than 7% were considered to have uncontrolled diabetes. The relationship between C-peptide index (CPI), PCGR index, and parameters related to glycemia and β cell function was investigated.

Results: Mean diabetes duration was 6.6±6 years and mean serum HbA1c level was 7.9±1.8%. There was a weak correlation between CPI and Homeostasis Model Assessment-β (HOMA-β), a moderate correlation between fasting C-peptide, delta C-peptide, and HOMA-β, and a strong correlation between fasting C-peptide, postprandial C-peptide, PCGR, and HOMA-β (p<0.05, p<0.05, p<0.001, respectively). There was a moderate negative correlation between postprandial C-peptide, delta C-peptide, fasting C-peptide-to-glucose ratio (FCGR), and serum HbA1c level (p<0.05). There was no correlation between fasting C-peptide and serum HbA1c level while there was a strong negative correlation between PCGR and serum HbA1c level (p<0.001). Comparison of the patient groups with and without glycemic control revealed that mean PCGR was significantly higher in the former group than the latter (p<0.001).

Conclusion: We conclude that PCGR is significantly associated with glycemic control and variability. Our data suggest that PCGR is a useful index indicating β-cell function, and it can be used in the individualization of DM treatment.
Mesothelioma - Diagnosis and treatment
Authors: Kasabalı Arzu , Erbaş Oytun
Published: February 2024

Malignant pleural mesothelioma (MPM) is a highly aggressive type of cancer more prevalent in males, although its most common etiology is exposure to asbestos fibers. Improvements in the prognosis of the disease are prevented due to the late manifestation of the disease, difficulties in diagnosis, and inadequate conventional treatments. In recent years, anti-cancer immunotherapy and treatments consisting of single or combined checkpoint inhibitors have been tested. Although programmed death-1 receptor, programmed death-ligand 1, and cytotoxic T-lymphocyte- associated protein 4 immunosuppressant checkpoint agents are promising for future developments, the studies showed that these approaches are currently inadequate due to toxicity problems and poor results. Despite the better understanding of carcinogenesis with new therapeutic approaches, further therapeutic research is needed for the treatment of MPM. A better understanding of multidisciplinary approaches is required to improve the prognosis of the disease and patient survival. Thus, it will be possible to develop more effective treatment strategies.
The role of shear wave elastography in determining molecular subtypes in breast cancer
Authors: Ağacayak Filiz , Özdil Güzide , İlgün Serkan , Mammadov Tural , Elbüken Filiz , Alço Gül , Erdogan Zeynep , İzci Filiz , Öztürk Alper , Nur Pilancı Kezban , Ordu Çetin , Duymaz Tomris , Aktepe Fatma , Özmen Vahit
Published: February 2024

Objectives: This study aimed to measure with shear wave elastography (SWE) the stiffness degree, which is a phenotypic reflection of the tumor in patients with breast cancer, and to manifest how the measured value relates to prognostic factors and molecular subtypes.

Materials and methods: This study included 99 female patients (mean age 48 years; range 29 to 78 years) diagnosed with breast cancer, underwent SWE, and received treatment at the Breast Health Center of Istanbul Florence Nightingale Hospital between January 2014 and March 2016. Those excluded were the patients who previously had an operation on the same breast or axillary fossa, who had noninvasive breast cancer, and who received neoadjuvant chemotherapy.

Results: A positively significant correlation was determined between the tumor diameter and the elastography value (p=0.001, r=0.32). There was no significant difference between elastography values of the tumors and histological type, intraductal component presence, histological grade, lymphovascular invasion, lymph node metastasis, Ki67 value, hormone receptor status, and molecular subtype.

Conclusion: In our study, it was shown that there was a positive correlation between elastography values and tumor size. No significant relationship was found between elastography values and other parameters. However, further studies with larger series may provide additional significant links.
Pengaruh Aktivitas Jasmani melalui Sepak Bola terhadap Kepercayaan Diri Orang dengan HIV Positif
Authors: Eka Putri Nadia
Published: February 2024

Abstrak

Abstrak Kepercayaan diri adalah perasaan yakin terhadap kemampuan diri sendiri tanpa rasa takut dan mampu menyelesaikan segala tantangan hidup tanpa membandingkan dengan kemampuan orang lain. Pernyataan tersebut tidak berlaku untuk orang dengan HIV positif karena stigma yang dilekatkan masyarakat terhadap mereka seperti kelompok pendosa, bersalah, penerima kutukan hingga azab membuat tingkat kepercayaan diri orang dengan HIV positif menjadi rendah. Aktivitas jasmani melalui sepak bola memiliki peran penting untuk merubah stigma dan menjadi salah satu cara orang dengan HIV positif dapat diterima oleh masyarakat tanpa memandang statusnya. Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas jasmani melalui sepak bola terhadap kepercayaan diri orang dengan HIV positif. Penelitian menggunakan metode penelitian kausal komparatif atau ex post facto. Pengambilan sampel menggunakan teknik purposive sampling dengan jumlah sampel orang dengan HIV positif sebanyak 5 orang yang mengikuti kegiatan sepak bola. Instrumen yang digunakan berupa kuesioner tertutup dengan menggunakan Skala Likert. Berdasarkan uji validitas kuesioner yang valid sebanyak 28 butir dari 50 butir pernyataan dan uji reliabilitas diperoleh hasil 0,722021 dan masuk dalam kriteria reliabel. Pengolahan dan analisis data diperoleh skor orang dengan HIV positif yang mengikuti kegiatan sepak bola sebesar 514 dari skor maksimal 700 setelah dipersentase hasilnya adalah 73,43%. Dengan demikian, peneliti dapat menyimpulkan bahwa aktivitas jasmani melalui sepak bola dapat berpengaruh terhadap kepercayaan diri orang dengan HIV positif.

Kata kunci: Aktivitas jasmani, Sepak Bola, Kepercayaan Diri, HIV positif
Hubungan Aktivitas Fisik dengan Tingkat Stres dan Kecemasan pada Day Traders Indonesia
Authors: Purnama Depi , Kusnaedi Kusnaedi , Ramania Nia Sri
Published: February 2024

Sejak pandemi COVID-19, animo masyarakat untuk melakukan day trading di bursa saham meningkat signifikan. Day trading menjanjikan keuntungan yang lebih cepat dan peluang profit setiap hari. Sayangnya, bidang ini berpotensi meningkatkan perilaku sedentary dan gangguan kesehatan mental yang terkait dengan stres dan kecemasan. Menghadapi ancaman tersebut, diketahui aktivitas fisik merupakan faktor pelindung untuk pencegahan dan penanggulangan permasalahan kesehatan akibat kurang gerak. Aktivitas fisik juga bermanfaat bagi kesehatan mental dan kesehatan secara menyeluruh. Penelitian ini bertujuan untuk menganalisis tingkat aktivitas fisik, tingkat stres dan kecemasan, serta korelasi antara aktivitas fisik dengan tingkat stres dan kecemasan pada day traders di Indonesia. Metode analisis korelasional dengan desain cross-sectional telah digunakan dalam penelitian ini. Instrumen International Physical Activity Questionnaire – Short Form (IPAQ-SF) dan Depression Anxiety and Stress Scale (DASS-21) digunakan sebagai alat pengumpulan data yang disebarkan secara online kepada komunitas trader di Indonesia (n = 392). Hasil uji statistik dengan Rank Spearman diperoleh nilai signifikansi antara aktivitas fisik dengan tingkat stres sebesar 0,000 (p<0,05), dan antara aktivitas fisik dengan tingkat kecemasan sebesar 0,000 (p<0,05), yang menunjukan bahwa ada korelasi antara aktivitas fisik dengan tingkat stres dan kecemasan. Subjek yang memiliki tingkat aktivitas fisik rendah sebesar 33,67%, aktivitas fisik sedang 40,56%, dan aktivitas fisik tinggi 25,77%. Sebagian besar subjek memiliki tingkat stres yang normal sebesar 68,62%. Begitu juga tingkat kecemasannya, rata-rata memiliki tingkat kecemasan normal sebesar 51,28%. Subjek dengan tingkat aktivitas fisik tinggi memiliki tingkat stres dan kecemasan yang lebih rendah, dan subjek dengan durasi screen time ≥ 4 jam, memiliki tingkat stres dan kecemasan yang lebih berat. Dari temuan ini, maka disarankan durasi screen time trading maksimal hanya 4 jam per hari, dan dianjurkan untuk melakukan aktivitas fisik seperti peregangan disela-sela kegiatan day trading.
Using neutron activation to assess heavy metal pollution in water and sediment along Savannah River
Authors: Nangeelil Krishnakumar Divakar , Fleming Colby , Sun Zaijing
Published: February 2024

A comprehensive study was conducted to assess heavy elemental pollution in the Savannah River, which flows through diverse landscapes encompassing agricultural, industrial, and commercial zones in South Carolina and Georgia. The investigation focused on the impacts of various anthropogenic activities on the river, potentially harming human health and aquatic ecosystems. Thirty samples, collected from the beginning of the Savannah River at Lake Hartwell to the Savannah River estuary near the Atlantic Ocean, were analyzed using Instrumental Neutron Activation Analysis. In regions of intense industrial activities, water samples exhibited elevated concentrations of elements such as Al (0.04-1.99 mg/L), Mg (0.4-5.5 mg/L), Ba (0.08-2.8 mg/L), Zn (0.017-0.9 mg/L), Cr (0.005-1.5 mg/L), and Fe (2.8-110.13 mg/L). Similarly, sediment samples near industrial areas also exhibited enhanced concentrations of heavy elements like Cr, Zr, Rb, Co, Zn, Mg, Mn, and Al. The outcome of this study has identified a spatial trend along the Savannah River, revealing major elements responsible for pollution that could disrupt the ecological environment and potentially impact human health.
The Pathway Towards Intergroup Forgiveness
Authors: Rungduin Darwin C. , Rungduin Teresita T.
Published: February 2024

Intergroup transgression is a form of  relationship that highlights differences among groups.  One aspect of this is emphasizing further discrepancies  between behaviors of members of the ingroup and  outgroup, which may develop antagonistic behaviors  against one another. When intergroup characteristics  become more salient, ingroup similarities become more  evident as well (Turner, 2012) which will consequently  inflate the chance of advancing the intergroup conflict.  The common ingroup identity theory (Dovidio, 2012)  proposes that re-categorization can be an approach by  which this conflict can be resolved. This re-categorization  rests on the assumption that if a superordinate identity  will be identified, the ingroup and outgroup members  will behave positively towards one another. This study  made use of a 2 x 2 between sample design with the first  factor consisting of priming and with the second factor as  socio-historical experience. Sixty-nine (69) respondents  participated in the experiment who were divided into two  groups: those who experienced martial law (cohort group)  and those who did not (non-cohort group). ANOVA  results indicated that neither priming nor socio-historical  group did not differ with one another and therefore did  not affect the perceived intergroup transgression and  intergroup forgiveness. The findings validated, however, the theoretical assumption that intergroup forgiveness can be facilitated by one's subscription to an overarching identity.
Development and Validation of an Achievement Test in Araling Asyano with Questions Addressing the K to 12 Araling Panlipunan Skills
Authors: Ebagat Winston E. , Dacanay Antonio G. , Simeon Florisa B.
Published: February 2024

The study aimed to develop and validate an achievement test in Araling Asyano for Grade 7 students that can measure the mastered and least mastered skills in the K-12 Araling Panlipunan. The researcher, together with a pool of experts, categorized the learning competencies of Araling Asyano, the result of which became the basis in preparing the test blueprint. Based on the test blueprint, a set of 150 questions with four options was formulated. The draft of the instrument was submitted to a panel of experts for content validation. Also, the test underwent two try-outs. After the final administration, a total of 65 items were included in the final form of the test. To ensure reliability, the achievement test underwent the process of test-retest method, split-half method, and KR-21 formula. Similarly, the data gathered through concurrent validity and known group technique of validation supported the validity of the instrument. The researcher concluded that the achievement test is valid and reliable for it covers the areas of Araling Asyano, and the items were responsive to the skills of K-12 Araling Panlipunan.
Tinjauan HAM Terhadap Kelompok LGBT di Kawasan Asia Tenggara
Authors: Andi Norman Nyila Amanda
Published: February 2024

Penelitian pada skripsi ini bertujuan untuk mengetahui : Bagaimana tinjauan terhadap hak azasi manusia kelompok LGBT di kawasan Asia Tenggara. Dalam penelitian ini digunakan metode penelitian deskriptif kualitatif. Pengumpulan data yang dilakukan oleh penulis adalah melalui pengumpulan dengan cara mengadakan wawancara berupa wawancara langsung (direct Interview) dan wawancara tidak langsung (indirect interview), serta laporan – laporan, jurnal, dan artikel yang didapatkan dari tempat penelitian, dan buku – buku yang berkaitan dengan objek penelitian. Teknik analisis data menggunakan teknik analisis data kualitatif yang diperoleh melalui penelitian lapangan di Komunitas Sehati Makassar (LGBT). Hasil temuan dari penelitian ini adalah bahwa dinegara Thailand kelompok LGBT menerima perlakuan yang cukup ramah dan bersahabat. Dalam kesehariannya kelompok Lesbian, Gay, Biseksual, dan Transgender (LGBT) cukup diberi ruang oleh masyarakat Thailand untuk mendapatkan hak – haknya termasuk hak untuk menyalurkan orientasi seksual yang dimiliki oleh setiap individunya. Sedangkan di negara Indonesia LGBT cukup sulit mendapat tempat untuk menjadi bagian dari masyarakat dikarenakan adanya penolakan yang cukup keras kepada mereka atas hak – hak untuk memnuhi orientasi seksualnya. perlakuan yang diterima oleh kelompok LGBT baik berupa penolakan maupun penerimaan yang terjadi pada kelompok LGBT di setiap negara disebabkan oleh adanya konstruksi sosial masyarakat atas LGBT mengenai hak azasi manusia (HAM) dan kelompok LGBT sehingga melahirkan ide atau gagasan yang terbentuk dari lingkungan masyarakat atas kelompok tersebut.
Pengaruh Konflik Rohingya Myanmar Terhadap stabilitas Kemanan Asia Tenggara
Authors: Surun Sri lusi rahmawati
Published: February 2024

Permasalahan dari konflik ini dalam hal stabilitas keamanan adalah pengungsi Myanmar melempar tanggungjawab dengan mengharapkan kepada negara-negara lain untuk dapat bisa menerima imigranimigran etnis Rohingya. Tujuan dari penelitain ini adalah untuk menganalisis dan membahas permasalahan kemanusiaan terkait Pengaruh Konflik Rohingya Myanmar terhadap Stabilitas Keamanan Asia Tenggara. Penelitian ini menggunakan metode deskriptif kualitatif yang bersifat menganalisa dan mendeskripsikan suatu permasalahan. Hasil penelitian menunjukkan bahwa Negara-negara ASEAN membuat kebijakan bahwa keputusan yang diambil dalam menghadapi konflik Rohingnya Myanmar berpegang teguh pada Masyarakat yang mengacu pada peraturan dengan kesamaan nilai dan norma, Kawasan yang kohesif, damai dan berdaya tahan tinggi dengan tanggung jawab bersama untuk menciptakan keamanan komprehensif, dan Kawasan yang dinamis dan berpandangan keluar. Semua negara anggota ASEAN memberikan bantuan penuh kepada penyelesaian konflik Rohingya tanpa membedakan SARA dengan melakukan diplomasi-diplomasi internasional. Tidak salah jika ASEAN sebagai organisasi regional diharapkan mampu untuk menyelesaiakan krisis tersebut dalam pencapaian stabilitas keamanan karena untuk mencapai suatu negara yang stabil diperlukan suatu kawasan yang stabil.
Dampak Implementasi Kebijakan Renewable Energy Directive II terhadap Hubungan Indonesia - Uni Eropa
Authors: Bukkang Yun Silva , Bt. Mamma Beche , Burhan Zulkhair
Published: February 2024

This research will write down the impact of implementing the Renewable Energy Directive II policy issued by the European Union to regulate the use of renewable energy as a form of the European Union's commitment to Sustainable Development Goals (SDGs). In the Renewable Energy Directive II Policy issued by the European Union, it is stated that palm oil causes deforestation or environmental damage. Indonesia, which has long established economic cooperation with the European Union, especially in the export-import of palm oil, as the world's largest producer of palm oil, feels discriminated against the policy issued. Indonesia gets the country's largest foreign exchange from exports of palm oil and its derivatives which will then have a major impact on the decline in imports of palm oil by the European Union after the issuance of this policy. This research question is "What is the impact of the implementation of the Renewable Energy Directive II policy on relations between Indonesia and the European Union?" to answer the questions in this study, researchers used the concept of International Political Economy by Robert Gilpin in explaining the results of this study. This study uses qualitative research methods using secondary data sources. The results of this study will answer the forms of tense relations between Indonesia and the European Union and what factors influence these tensions to occur. This research will also explain the beginning of the cooperation between Indonesia and the European Union and how the relationship was before and after the Renewable Energy Directive II policy was made.
Navigating Language Diversity In Multilingual Stem Classrooms: Strategies For Inclusive Education
Authors: Mokikwa Hamza , Mokhele-Ramulumo Moleboheng
Published: February 2024

In multilingual STEM classrooms, language diversity presents challenges and opportunities for inclusivity. This study examines the impact of language diversity on STEM education, emphasizing its relevance in a globalized context. By employing a mixed-methods approach, including surveys and interviews with students, educators, and administrators, we identify patterns in the interplay between language diversity and inclusive education. Preliminary findings highlight challenges such as communication barriers and opportunities for enriched problem-solving. The discussion emphasizes recognizing linguistic diversity as an asset and suggests strategies to address barriers, advocating for a supportive, inclusive classroom. Implications for educators, policymakers, and researchers underscore leveraging linguistic diversity as a strength, with recommendations including professional development, integrating diverse perspectives into STEM materials, and implementing inclusive language policies for a more equitable STEM education landscape.
Dicamba-Based Herbicide Programs, Cropping Sequences, Tillage Types in Cotton – Profitability and Risk Efficiency Analysis
Authors: Vulchi Rohith , Zapata Samuel , Nolte Scott , Robinson John , McGinty Joshua
Published: February 2024

Herbicide-resistant weeds threaten cotton production, and herbicides alone are not a sustainable remedy. Field trials at two locations, College Station and Thrall, Texas (2019-21), assessed dicamba-based herbicide programs in various crop sequences and tillage systems to identify sustainable weed management recommendations based on weed control and partial net returns. The study showed no-till cover cropping and conventional tillage had the highest aggregate partial net returns at College Station and Thrall, respectively. A cotton:sorghum:cotton rotation provided significantly higher partial net returns (>$450 ha-1) compared to continuous cotton only at Thrall. Partial net returns were significantly higher in a low input herbicide program (LI) compared to a high input herbicide program (HI) from 2019-21 only at Thrall. Herbicide programs showed a high degree of overlap and were indistinct in all tillage types at College Station based on CDFs graphs. Low input under cotton:sorghum:cotton rotation showed 100% probability of higher partial net returns compared to continuous cotton in all tillage types at Thrall. Stoplight charts showed LI provided greater than 50% probability of partial net returns greater than $1,066 ha-1 across tillage types at College Station. In Thrall, LI under cotton:sorghum:cotton rotation offered 88% and 26% probability of partial net returns above $1,066 ha-1 in conventional and strip tillage, respectively. Higher partial net returns for LI were mostly attributed to cost savings from using inexpensive herbicides rather than higher yields. Therefore, using less expensive herbicide programs and crop rotation appeared to be the most risk efficient strategy for managing weeds in irrigated and dryland cotton production.
Palmer Amaranth (Amaranthus palmeri) Control in Dicamba-Tolerant Cotton (Gossypium hirsutum) when Applied with Various Dicamba + Insecticide Tank-Mixtures
Authors: McNeal Jacob , Dodds Darrin , Catchot Angus , Gore Jeffrey , Irby Trent , Kruger Greg
Published: February 2024

Postemergence herbicide application timings for Palmer amaranth (Amaranthus palmeri) often coincide with foliar insecticide applications in cotton (Gossypium hirsutum). Combining multiple pesticides into a single application increases efficiency while reducing overall application cost. Multiple foliar insecticides are now labeled for dicamba tank-mixes. However, there is limited literature with respect to efficacy of dicamba on Palmer amaranth control when applied with insecticides. Field experiments were conducted from 2018 to 2020 to evaluate the effect of carrier volume and insecticide on the efficacy of dicamba (XtendiMaxTM with VaporGripTM) to control Palmer amaranth in XtendFlex™ cotton production systems. Dicamba was tank-mixed with acephate and dimethoate to four-leaf cotton and with thiamethoxam and sulfoxaflor just prior to bloom. Applications were made at carrier volumes of 140 and 280 L ha-1 and with a single spray droplet size of 800 µm. Palmer amaranth control 7 d after treatment was negatively impacted when applications included dimethoate; however, no corresponding response in seedcotton yield was observed relative to dicamba applied alone. However, when pooled over carrier volume, applications containing dicamba + acephate resulted in higher seedcotton yield than applications of dicamba + dimethoate. Additionally, pre-bloom applications of dicamba + thiamethoxam or sulfoxaflor increased Palmer amaranth efficacy relative to dicamba applied alone. Although certain insecticides are known to increase herbicidal crop response, the impact of insecticides on herbicide efficacy to control specific weed species is largely unknown. Therefore, we conclude that multiple dicamba + acephate, thiamethoxam, or sulfoxaflor tank-mixtures provide similar control of Palmer amaranth compared to dicamba alone.
BƯỚC ĐẦU ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT MỞ SỌ GIẢI ÉP KẾT HỢP MỞ BỂ DỊCH NÃO TỦY NỀN SỌ ĐIỀU TRỊ CHẤN THƯƠNG SỌ NÃO NẶNG TẠI BỆNH VIỆN QUÂN Y 103
Authors: Nguyễn Thành Bắc , Nguyễn Văn Nam , Nguyễn Mạnh Trường , Nguyễn Xuân Phương
Published: February 2024

Mục tiêu: Bước đầu đánh giá kết quả và biến chứng của phẫu thuật mở sọ giải ép (MSGE) kết hợp mở bể dịch não tủy nền sọ điều trị chấn thương sọ não nặng (CTSNN). Phương pháp nghiên cứu: Nghiên cứu tiến cứu, can thiệp không đối chứng, mô tả cắt ngang kết hợp theo dõi dọc trên 16 trường hợp CTSNN được MSGE đồng thời mở bể dịch não tủy nền sọ. Đánh giá kết quả ở thời điểm ra viện và sau ra viện 03 tháng. Kết quả: Tuổi trung bình là 53,19; 75% bệnh nhân (BN) nam, GCS (Glasgow Coma Scale) trung bình trước can thiệp là 7 ± 1,15; 81,25% BN trước mổ không có giãn đồng tử, phản xạ ánh sáng (PXAS) (+), 87,5% BN không liệt vận động. Trên cắt lớp vi tính (CLVT) phần lớn BN có kết hợp các loại máu tụ (81,25%) và chảy máu màng nhện (87,5%), lệch đường giữa 5 - 10mm chiếm tỷ lệ cao nhất (43,75%); 75% BN có bể đáy bình thường. Sau phẫu thuật, áp lực nội sọ (ALNS) giảm có ý nghĩa thống kê so với trước mổ (46,06 ± 9,69 so với 18,94 ± 3,30 mmHg; giảm 27,13 ± 9,00; p < 0,001). Ở thời điểm ra viện, 81,25% BN sống sót, sau 03 tháng là 84,6%, tỷ lệ phục hồi chức năng thần kinh tốt là 38,4%. Tỷ lệ biến chứng sớm là 12,5% và muộn là 27,3%. Kết luận: Bước đầu đánh giá phẫu thuật MSGE kết hợp mở bể dịch não tủy nền sọ điều trị CTSNN cho thấy phương pháp này có hiệu quả kiểm soát ALNS.
ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT NỘI SOI XỬ TRÍ KHỐI U BUỒNG TRỨNG XOẮN TẠI BỆNH VIỆN QUÂN Y 103
Authors: Đào Nguyên Hùng , Lê Thị Vân Trang , Hoàng Văn Sơn
Published: February 2024

Mục tiêu: Đánh giá hiệu quả của phẫu thuật nội soi xử trí khối u buồng trứng xoắn tại Bệnh viện Quân y 103 từ tháng 01/2019 - 7/2023. Phương pháp nghiên cứu: Nghiên cứu hồi cứu, mô tả cắt ngang trên 44 bệnh nhân (BN) được chẩn đoán và điều trị phẫu thuật nội soi khối u buồng trứng xoắn tại Bệnh viện Quân y 103 từ tháng 01/2019 - 7/2023. Kết quả: 16 BN được điều trị bằng phương pháp bóc u bảo tồn buồng trứng (36,36%) và 28 BN được điều trị bằng phương pháp cắt buồng trứng chứa u (63,64%). 72,73% BN sử dụng kháng sinh dự phòng sau mổ. BN dùng một liều giảm đau chiếm tỷ lệ cao nhất (79,55%) và không cần dùng giảm đau chiếm 11,36%. 81,82% BN ngồi dậy được trong ngày đầu sau mổ và 79,55% BN đi lại được trong ngày thứ 2 sau mổ. 95,46% BN trung tiện được trong vòng 24 giờ sau mổ. Thời gian nằm viện sau mổ từ 3 - 5 ngày chiếm tỷ lệ lớn nhất (56,81%). Thời gian nằm viện trung bình sau mổ là 4,16 ± 1,73 ngày. Kết luận: Phẫu thuật nội soi xử trí khối u buồng trứng xoắn giúp BN hồi phục sau mổ tốt, rút ngắn thời gian nằm viện và giảm chi phí điều trị.
Artroscopia de muñeca: Una técnica mínimamente Invasiva
Authors: Aldaz Santamaría Mónica Patricia
Published: February 2024

La artroscopia de muñeca, desde su introducción en la década de 1970, ha evolucionado significativamente como herramienta diagnóstica y terapéutica. Ha superado obstáculos técnicos, expandiendo indicaciones y mejorando instrumentación. La técnica se ha vuelto común en cirugía de muñeca, con avances recientes como la anestesia local sin torniquete. Aunque presenta riesgos y costos adicionales, ofrece beneficios como visualización directa y precisión en procedimientos como la reducción de fracturas. La literatura destaca su seguridad y eficacia, aunque se deben considerar posibles complicaciones. El continuo desarrollo tecnológico y la investigación impulsan su aplicación clínica. Proporcionar una visión general de la artroscopia de muñeca, incluyendo sus indicaciones, técnicas, avances recientes y posibles complicaciones. Se seleccionaron estudios relevantes publicados en los últimos 5 años utilizando métodos cuantitativos, cualitativos y mixtos que cumplieran con criterios de inclusión e información relevante. La búsqueda se llevó a cabo en varias bases de datos, como PubMed, Elsevier, Journal of Wrist Surgery, Journal of Arthroscopic Surgery and Sports Medicine, Annals of Joint, Acta Orthopaedical y Journal of Hand Surgery en relación con la artroscopia de muñeca. La artroscopia de muñeca es una técnica mínimamente invasiva para diagnosticar y tratar afecciones. Aunque es efectiva en ciertos casos, no se demostraron beneficios significativos en comparación con otras intervenciones en algunos estudios. El puntaje DASH, el dolor y la mejoría se evalúan, pero se necesitan más ensayos clínicos para confirmar su eficacia. A pesar del aumento en su uso, la evidencia aún no es concluyente. La capacitación especializada es crucial. La artroscopia de muñeca sigue siendo una opción prometedora, pero se requiere más investigación para comprender completamente su papel y beneficios.
Türkiye’nin Savunma ve Havacılık Sanayii ve İhracatı’nın Analizi (2002-2023)
Authors: ÇANKAYA BAYRAKLI Zehra
Published: February 2024

Türkiye’nin bir yandan askeri, siyasi ve ekonomik olarak bölgesinde güçlü bir aktör haline gelmesi diğer yandan ise Türk Silahlı kuvvetlerinin ihtiyaçlarını yerli kaynak ve teknolojilerden elde etme çabası savunma ve havacılık sanayi sektörünün son yıllarda hızla büyümesini sağlamıştır. Türk havacılık ve savunma sanayiindeki gelişmeler, özellikle 2002 sonrası ülke ekonomisinin gelişmesinde, istihdam artışında, inovasyon ve Ar-Ge çalışmaları çerçevesinde ciddi katkılar sağlamıştır. Bu makale 2002-2023 yılları arasında savunma ve havacılık sanayii ve ihracatının ekonomi-politik açıdan analizini yapmayı hedeflemektedir. Bu çalışmada Stockholm Uluslararası Barış Araştırmaları Enstitüsü(SIPRI), Kuzey Atlantik Antlaşması Örgütü (NATO), Savunma ve Havacılık Sanayii İmalatçıları Derneği (SASAD), Savunma Sanayii Başkanlığı (SSB) ve Türkiye İhracatçılar Meclisi (TİM) verilerine dayanarak savunma sanayii incelenmeye, analiz edilmeye çalışılmıştır. Savunma Sanayii; Türkiye’nin ivme kazanan sektörü olmasının yanında 2023 ihracat kalemleri içerisinde diğer sektörlere kıyasla daha fazla yükselişe geçen ihracat alanı olmuştur. İhracat yapılan ülkeler bazında değerlendirme yapıldığında son yıllarda Körfez İşbirliği Konseyi(KİK) ülkeleriyle yapılan anlaşmalar göze çarpmaktadır. Bu iş birlikleri bölgesel olarak istikrar ve güvenliği sağlamak, ekonomik kalkınmayı teşvik etmek açısından önemli gözükmektedir. KİK ülkeleri dışında Afrika devletlerine yapılan savunma sanayii ihracatları da son dönemde artmıştır. Türk savunma ve havacılık sanayiinin, yerli kaynaklarla üretilen ileri teknoloji ürünler sayesinde ülke güvenliğine katkı sağlamasının yanı sıra yüksek ihracat potansiyeline de sahip olduğu incelenen verilerden anlaşılmaktadır.
Implementing best practice in Alberta: A diabetes foot care clinical pathway
Authors: Dmytruk Kathy , O'Connell Petra
Published: February 2024

There are significant variations in foot screening practices in Alberta. Despite best prac-tice guidelines, many primary care providers do not perform the recommended annual foot exam-ination on their patients with diabetes. This highlights the need for a systematic approach to increase screening practice across Alberta.
دور حاضنات الأعمال في تعزيز ريادة الأعمال
Authors: جاسم Tarik , عبد الدائم Zeena
Published: February 2024

يهدف البحث إلى معرفة دور حاضنات الأعمال في تعزيز ريادة الأعمال، و يهدف أيضاً إلى التعرف على مستوى توفر الخدمات (الخدمات التمويلية، الخدمات الإدارية والسكرتارية، خدمات الأستشارات القانونية، خدمات البنية التحتية، والخدمات التسويقية) في حاضنة وزارة التعليم العالي والبحث العلمي العراقية/ دائرة البحث والتطوير، وأعتمد الباحث المنهج الوصفي التحليلي في إنجاز البحث، وتم أعتماد الأستبانة كأداة لجمع البيانات المطلوبة، وقد تم مسح مجتمع الدراسة والمكون من أصحاب المشاريع المحتضنين من قبل حاضنة الوزارة والبالغ عددهم (53) مشاهدة، وقد قام الباحث بتحليل مخرجات الأستبانة إحصائياً ومعالجتها بواسطة برنامج spss v.24. وقد توصل البحث إلى أهم الأستنتاجات  وهي ضعف في مستوى تقديم الخدمات التمويلية ، وهذا عائد على أفتقار الحاضنات للدعم المالي لمشاريعها، وأيضاً فشلها في إعداد ميزانيتها الذي قد يكون له الأثر في ذلك.
Edukasi Pembuatan Paper Seed dari Limbah Kertas dengan Carbon Dots Pisang sebagai Media Pembelajaran di Min 1 Jembrana
Authors: Martanto Wahyu Hadi
Published: February 2024

Dalam upaya meningkatkan kualitas pendidikan di Indonesia, Menteri Pendidikan dan Kebudayaan, Nadiem Makarim, memperkenalkan Kurikulum Merdeka sebagai respons terhadap hasil penilaian peserta didik dalam Programme for International Student Assessment (PISA) yang menunjukkan penempatan yang rendah. Kurikulum Merdeka menekankan konsep kemandirian dan kemerdekaan bagi lembaga pendidikan untuk menentukan metode dan pendekatan terbaik yang sesuai dengan konteks local. Dengan mengintegrasikan pemahaman tentang pendidikan kebebasan, Kurikulum Merdeka, dan pemanfaatan sumber daya lokal seperti kulit pisang, penelitian ini bertujuan untuk mengembangkan media pembelajaran yang inovatif untuk pembuatan kertas dari limbah kulit singkong. Penelitian ini mencoba menggabungkan konsep pendidikan yang merdeka dan memanfaatkan sumber daya lokal yang berkelanjutan dalam proses pembelajaran. Dengan demikian, media pembelajaran ini dapat menjadi alat efektif untuk meningkatkan kesadaran lingkungan, kemandirian, dan pemikiran kritis peserta didik di MIN 1 Jembrana. Metode penelitian meliputi persiapan alat dan bahan, prosedur pembuatan seed paper, tahap perencanaan dan persiapan, serta tahap evaluasi dan analisa data. Hasil penelitian menunjukkan bahwa peserta pelatihan berhasil meningkatkan pengetahuan mereka tentang pembuatan Paper Seed dari limbah kertas dan penggunaan nanodots pisang kepok. Secara keseluruhan, penggunaan media pembelajaran "Edukasi Pembuatan Paper Seed dari Limbah Kertas dengan Carbon dots Pisang" memiliki dampak positif terhadap pemahaman siswa tentang proses pembuatan kertas, kesadaran lingkungan, dan konsep kemandirian dalam pembelajaran.
FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA USAHA PADA NASABAH KUR BRI SEMARANG
Authors: Lia Ariani  , Ratih Hesty Utami Puspitasari  , Qristin Violinda
Published: February 2024

This study aims to determine the factors that influence the business performance of BRI KUR customers, Pattimura Branch, Semarang. The sampling technique used was purposive sampling technique, the number of samples taken was 140 respondents. The data analysis method used is multiple linear regression analysis using SPSS version 22. The results of this study indicate that own capital has a positive and significant effect on business performance with a t-count value of (5.694) greater than a t-table value of (1.656) and a significance level of (0.000) is less than the minimum significance level of (0.05). People's business credit capital has a positive and significant effect on business performance with a t-count value of (2.077) greater than the t-table value of (1.656) and a significance level of (0.040) smaller than the minimum significance level of (0.05) . Length of business has a positive and significant effect on business performance with a t-count value of (4.676) greater than the t-table value of (1.656) and a significance level of (0.000) less than the minimum significance level of (0.05).
An Analysis of Paraphrasing Techniques Used by Student at the Fifth Grade English Education Department of IAIN Bukittinggi Academic Year 2022/2023
Authors: Zohra Meilanie , Melani Melyann , Roza Veni , Prima Dewi Merry
Published: February 2024

This research was conducted based on the problem found in academic writing class about paraphrasing at English Education Department at the fifth semester IAIN Bukittinggi. Paraphrasing is known as a way to avoid plagiarism while creating scientific papers or journals. However, the researcher interviewed the lecturer and found that the most of the students have difficulty putting the ideas into their own words. They used too many words from the original passage that shows the students were lack of vocabulary mastery. Moreover, the students used monotonous technique of paraphrase. This research used mixed method. It is a procedure for collecting, analyzing, and mixing both quantitative and qualitative methods in a single study or a series to understand a research problem. The students were given a paraphrasing test to know the students ability. The data were analyzed using scoring rubric proposed by Callison. After that, some students were interviewed to find out the dominant paraphrasing technique used by the students. After calculating the score, the result of the study showed that the student’s ability in paraphrasing was 59. As writing band suggested by Leo, the students’ ability in paraphrasing is in moderate level where it is rather well organized. Arguments are rather relevant in relation to writer’s view. Main ideas and supporting ideas are rather clear. The message is almost clear but with some loss of detail. In addition, the interview showed that most of the students use synonym replacement technique in paraphrasing the text. It is because most of the student agreed that the technique is the easiest technique to use.
Code-Switching: A Strategy to Increase Students Participation In Efl Classroom Interaction
Authors: Taufiq M. Aries , Eka Putri Rahmi , Asmawati Asmawati
Published: February 2024

This article aims at describing code-switching (CS) as a strategy to increase students’ participation in EFL classroom interaction. Currently, EFL students are discouraged to participate in the classroom. Their English proficiency becomes the major problem initiated this situation. Obligating the students to speak fully English during the classroom interaction forced them to be silent all the time. Code-switching (CS) was considered to offer a solution for this unsatisfied condition in which the students can switch the language whenever they need. This descriptive study was conducted to reveal the role of code-switching in enhancing students’ participation in the classroom interaction. Switching from English to Indonesian demonstrated an improvement of students’ participation in the classroom interaction. This study found that code-switching provided students an opportunity to interact more effectively in the classroom. By switching the language, the students felt more confident to participate in the classroom and they began to be more active during the classroom interaction
Abstrak
Artikel ini bertujuan untuk menjelaskan alih kode (CS) sebagai sebuah strategi untuk meningkatkan partisipasi siswa dalam interaksi di kelas EFL. Saat ini, siswa enggan untuk berpartisipasi didalam kelas karena rendahnya kemampuan bahasa Inggris yang mereka punya. Mengharuskan siswa untuk selalu menggunakan bahasa Inggris didalam kelas memaksa mereka untuk menjadi siswa yang pasif. Alih kode menawarkan solusi bagi siswa untuk lebih aktif di kelas karena mereka dapat mengalihkan bahasa kapanpun dibutuhkan. Penelitian deskriptif ini dilakukan untuk mengungkapkan peran alih kode dalam meningkatan partisipasi siswa di kelas. Mengalihkan dari bahasa Inggris ke bahasa Indonesia terbukti meningkatkan partisipasi siswa dalam interaksi di kelas. Penelitian ini menemukan bahwa alih kode membantu siswa berinteraksi dengan lebih efektif. Dengan mengalihkan bahasa, siswa merasa lebih percaya diri untuk berpartisipasi di kelas.
A Study on Mechanical/Metallurgical Characteristic of Welded Joints According to Heat Input and Gap in Al/Cu Laser Welding
Authors: Lee Chan Yang , Oh Min Chul
Published: February 2024

The electrical connectivity and tensile strength between battery components are crucial factors for enhancing battery performance in electric vehicles. In this study, the welding characteristics of aluminum-copper welded joints manufactured using the multi-core laser welding process were studied according to the output power of core/ring laser. Moreover, the tensile strength change behavior according to various welding processes, such as single/two-line welding, and welding gap distance were measured. The results revealed that increasing the output power of the ring beam led to an increase in the tensile strength. However, excessive laser power would increase convection between aluminum and copper during welding and cause defects owing to the difference in the solidification temperature between the two materials. In addition, the mechanical properties were improved by increasing the distance between the two lines of straight laser welding. As the spacing increased, the fraction of the equiaxed microstructure increased, and grain growth was suppressed to improve mechanical properties.
Review on Laser Welding Technology on Aluminum and Copper Dissimilar Materials for Secondary Batteries Assembly
Authors: Cho Jaewoo , Lee Taehyun , Bang Heeseon , Hyun Soongkeun , Kim Cheolhee
Published: February 2024

Electric vehicles have recently taken center stage, driven by growing environmental concerns, with a key focus on ensuring the reliability of their batteries. The materials used in the electrical connections of secondary batteries predominantly consist of Al and Cu alloys, necessitating the joining of both similar and dissimilar materials. This paper presents a technical review on laser welding technology applied to the challenging Al/Cu dissimilar metal combination. The complexity arises from the formation of brittle phases in intermetallic compounds and the low absorption of laser beams by the base materials. The characteristics of various laser welding modes and their effective monitoring through deep learning are explained in detail. The development of real-time laser welding monitoring technology is crucial to increase productivity and enable the mass production of reliable electric vehicle battery systems.
Assessment of Ttensile-Shear and T-Peel Strengths for Cu-STS 304 Dissimilar Overlap Welded Joints using Single-Mode Fiber Laser with High Welding Speeds
Authors: Eun Youngjin , Kang Sanghoon , Kang Minjung
Published: February 2024

This study focused on the mechanical and metallurgical properties of Ni-coated pure copper (0.2 mm thick) and stainless steel 304 (0.4 mm thick) dissimilar joints fabricated using single-mode laser welding. Overlap and T-peel welded joints were produced using different welding parameters, such as the laser power and speed. The laser-welded specimens were tested by tensile tests of the weldments, optical metallography, and chemical composition examination of the intermediate layer using energy dispersive X-ray spectroscopy (EDS). The welded joint configuration showed the largest influence on the failure strength. The tensile-shear strengths were more than 3.7 times higher than the T-peel strengths. The scanning electron microscopy and EDS analyses confirmed heterogeneity of the elemental composition across the welded joint interface, regardless of the welding parameters, with minimal occurrence of hot cracks within the welds.
Overexpression and Downregulation of HOTAIR Influence the Stemness Markers in Gastric Cancer Cell Lines
Authors: Ghanadpour Morteza , Bossaghzadeh Fatemeh , Galehdari Hamid , Kazemi Nezhad Seyed Reza , Tahmasebi-Birgani Maryam , Hajjari Mohammadreza
Published: February 2024

Background: Several long non-coding RNAs are implicated in the development and metastasis of cancer. The non-coding RNA HOTAIR is known to play a significant role in the progression of various cancers. Objectives: This study aimed to assess the impact of HOTAIR dysregulation on stemness markers in AGS and MKN45 gastric cancer cell lines. Methods: Downregulation and upregulation of HOTAIR were induced using small interfering RNA (siRNA) and a HOTAIR overexpression vector, respectively. The surface stemness markers CD24 and CD44 were analyzed using flow cytometry. Additionally, the effects on the expression of two stemness markers, NANOG and P21, were investigated using Quantitative Reverse Transcription PCR (qRT-PCR). Results: Flow cytometry analysis showed that HOTAIR modulates the cell-surface expression of CD44 and CD24 in gastric cancer cells. Furthermore, dysregulation of HOTAIR significantly affected the expression of the genes P21 and NANOG. Conclusions: Our studies suggest that HOTAIR may regulate the stemness characteristics of gastric cancer cell lines.