bluuebunny/crossref_metadata_2025 huggingface dataset:
Meeting Abstract 2024
Authors: Tolunay Orkun
Published: November 2024

Turkish Journal of Pediatrics
1st Ankara Bilkent City Hospital, Pediatrics Congress 17-19 October 2024, Presentation Abstracts
Getting involved with the ACPN committee
Authors: Burch Jennie
Published: November 2024

Jennie Burch details the range of committees available through the Association of Coloproctology Nurses, and spotlights their respective tasks and responsibilities.
Promoting new competencies in liver care
Authors: Hill Rebekah
Published: November 2024

Rebekah Hill provides an update of the RCN's recent liver-orientated initiatives.
Lord Darzi's NHS review: gastrointestinal nursing implications
Authors: Harrison Penny
Published: November 2024

Penny Harrison discusses the findings of the Darzi report and explores its recommendations for future development of the NHS.
Prevention and management of diabetic foot problems
Authors: Nazarko Linda
Published: November 2024

Linda Nazarko looks at these common and painful complications experienced by diabetic patients
Trichomoniasis: A guide for primary care nurses
Authors: Perry Margaret
Published: November 2024

Margaret Perry looks at what nurses need to know about this common sexually transmitted infection
Effects of polymorphisms in PIT1, H-FABP, PIK3C3 and CAST genes on chemical composition, amino acid content in meat of Vietnamese indigenous fatty pig breed “I”
Authors:   Department of Animal Science, Faculty of Agriculture - Forestry - Fishery, Hong Duc University, Quang Trung, Thanh Hoa 40132, Vietnam, Tuoi Phan Thi ,   Department of Animal Breeding and Genetics, Faculty of Animal Science, Vietnam National University of Agriculture, Gia Lam, Hanoi 12406, Vietnam, Anh Nguyen Thai ,   Department of Animal Breeding and Genetics, Faculty of Animal Science, Vietnam National University of Agriculture, Gia Lam, Hanoi 12406, Vietnam, Manh Tran Xuan ,   Dabaco Nucleus Breeding Pig Company, Tien Du, Bac Ninh 16416, Vietnam, Hung Nguyen Van ,   Dabaco Nucleus Breeding Pig Company, Tien Du, Bac Ninh 16416, Vietnam, Phuong Do Thi ,   Sunjin Vina Co., Ltd – Ha Nam Branch, Ha Nam 400000, Vietnam, Xoan Mai Thi ,   Department of Animal Science, Faculty of Animal husbandry and Veterinary, Tay Nguyen University, Buon Ma Thuot, Dak Lak 63000, Vietnam, Thinh Nguyen Hoang ,   Department of Animal Breeding and Genetics, Faculty of Animal Science, Vietnam National University of Agriculture, Gia Lam, Hanoi 12406, Vietnam, Luc Do Duc ,   Department of Animal Breeding and Genetics, Faculty of Animal Science, Vietnam National University of Agriculture, Gia Lam, Hanoi 12406, Vietnam
Published: November 2024

This study aimed to evaluate the effects of polymorphisms of PIT1/RasI, H-FABP/HinfI, PIK3C3/Hpy8I, CAST/HinfI genes and gender on chemical composition, amino acid content in meat of Vietnamese indigenous fatty pig breed “I” raised under industrial condition at Dabaco Breeding Pig Company, Phu Tho Province, Vietnam. Samples of longissimus dorsi muscle from 23 “I” pigs (12 gilts and 11 barrows) at 8 months of age were used to measure chemical composition (dry matter, protein, lipids and ash) and content of 17 amino acids (aspartic, glutamic, serine, histidine, glycine, threonine, alanine, arginine, tyrosine, valine, methionine, phenylalanine, isoleucine, leucine, lysine, proline, cystine); while ear tissues were collected to identify polymorphisms of these genes. Chemical compositions were analyzed using ISO methods (1973, 1978, 1997, and 1998). The content of amino acids was quantified using high-performance liquid chromatography (HPLC) methods. The polymorphisms of four genes were identified by the PCR-RFLP technique. The results indicated that PIT1, H-FABP, PIK3C3, and CAST had no effects on chemical compositions and amino acid contents (P>0.05). Inversely, the contents of amino acids (aspartic, serine, threonine, arginine, phenylalanine, leucine, and lysine) were significantly different between gilts and barrows (P<0.05).
Isolation, molecular identification, and pathogenicity of Aeromonas hydrophila disease in clown knife fish (Chitala chitala) in the Mekong Delta, Vietnam
Authors:   College of Aquaculture and Fisheries, Cantho University, Can Tho City 90000, Vietnam., Dung Tu Thanh , Cao Thi Quach Van ,   Faculty of Applied Biological Sciences, Vinh Long University of Technology Education, Vinh Long City 89000, Vietnam, Trung Nguyen Bao ,   College of Aquaculture and Fisheries, Cantho University, Can Tho City 90000, Vietnam
Published: November 2024

Hemorrhagic septicemia disease caused by Aeromonas hydrophila bacteria appears to be more common and causes severe damage to many fish species worldwide. This research aimed to isolate, identify, and determine the pathogenicity and antibiotic susceptibility of A. hydrophila in septicemic clown knife (Chitala chitala) fish in the Mekong Delta, Vietnam. As a result, 116 bacterial strains were isolated from 176 septicemic fish samples. Two strains of bacteria, D2F71 and H1F39, were identified as A. hydrophila based on colony morphology, identification results by the API 20E kit, PCR technique, and aerolysin gene sequencing. In addition, these two strains of bacteria were experimentally infected on healthy clown knife fish (weight 15±4 g/fish) by injection method. The experimental results fulfilled Koch's postulates: infected fish showed signs of disease symptoms similar to those of naturally diseased fish. In particular, the two strains of bacteria D2F71 and H1F39 in the experiment had relatively high virulence, with LD50 values of 1.26×104 CFU/mL and 4.06×103 CFU/mL, respectively. The obtained findings demonstrated that the bacteria were susceptible to doxycycline, florfenicol, cefotaxime, flumequine, enrofloxacin, and sulfamethoxazole-trimethoprim at a rate of over 70%. On the contrary, the study found that bacterial isolates were resistant to ampicillin (100%), cefazolin (85%), streptomycin (80%), and colistin (80%). To our knowledge, this is the first report on hemorrhagic septicemic clown knife fish caused by A. hydrophila in Vietnam.
Urolithiasis and the effectiveness of treatments in dogs and cats in Ho Chi Minh City, Viet Nam
Authors:   Faculty of Veterinary and Animal Science, HUTECH University, Binh Thanh District, Ho Chi Minh City 717000, Viet Nam, Hong Loan Nguyen Vu Thuy , Dao Dang Hoang ,   Faculty of Veterinary and Animal Science, HUTECH University, Binh Thanh District, Ho Chi Minh City 717000, Viet Nam
Published: November 2024

This study aimed to investigate the prevalence of urolithiasis, analyze the chemical composition and anatomical location of the stone, and evaluate the effectiveness of treatments in dogs and cats. The investigation lasted one year in 7 Veterinary Clinics in the urban area of Ho Chi Minh City. Results show that urolithiasis accounted for 37.1% of total cases of dogs and cats, and that cats are more sensitive to urolithiasis than dogs (44.93% vs 27.90% of total population). Some risk factors such as sex, type of food and levels of drinking water affect urolithiasis rate, in which male animals and low levels of drinking water are more sensitive to urolithiasis than females and adequate levels. Lower urinary stones are common in dogs (74.05% of cases) and in cats (88.00% of cases). Struvite stones in dogs (62.00% of cases) and calcium oxalate in cats (56.00% of cases) are the most common type of urinary stones. Medical treatment is the most effective method to treat urolithiasis in cats and dogs.
Evidence of histopathological appearances in representative fishes and invertebrates from Libong Island, Thailand
Authors:   Department of Aquaculture and Fishery Products, Faculty of Science and Fisheries Technology, Rajamangala University of Technology Srivijaya, Trang 92150, Thailand, Phinrub Wikit , Dahlan Nisreen ,   Department of Marine Science and Environment, Faculty of Science and Fisheries Technology, Rajamangala University of Technology Srivijaya, Trang 92150, Thailand, Senarat Sinlapachai ,   Department of Marine Science and Environment, Faculty of Science and Fisheries Technology, Rajamangala University of Technology Srivijaya, Trang 92150, Thailand,   Division of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand, lida Atsuo ,   Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan, Charoenphon Natthawut ,   Department of Anatomy, Faculty of Medical Science, Naresuan University, Phitsanulok 65000 Thailand, Thaochan Narit ,   Agricultural Innovation and Management Division, Faculty of Natural Resources, Prince of Songkla University, Songkhla 90110 Thailand, Angsujinda Kitipong ,   Aquatic Resources Research Institute, Chulalongkorn University, Bangkok 10330, Thailand, Imsonpang Supapong ,   Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand
Published: November 2024

The seagrass beds at Libong Island, Thailand, are a complex ecological habitat supporting many marine organisms. Unfortunately, the seagrass area is being lost, possibly exerting adverse impacts on aquatic life, but comprehensive aquatic monitoring and assessment efforts are still lacking. In this study, sentinel species were selected from two species groups commonly found in this area, pelagic species (Ambassis nalua and A. vachelli) and benthic species (Amphibalanus amphitrite, and Alpheus sp.). Specimens were collected from healthy and unhealthy seagrass areas around the island from April to June 2021. The health of the specimens was assessed using the histopathological approach together with the histological alteration index (HAI). Some histological alterations were identified that HAl values indicated were significantly more prevalent in the unhealthy seagrass areas (P<0.05). Among the invertebrates, A. amphitrite exhibited melanomacrophage centers while Alpheus sp. exhibited lamellar disorganization in gill and degeneration of hepatopancreatic cells. The two fish species exhibited vacuolar degeneration in the liver that was more pronounced in specimens from the unhealthy seagrass area. However, the HAI values calculated for all samples ranged from 0.1 to 1, indicating normal organs. These results suggest the emergence of environmental alteration in the threatened seagrass habitats at Libong Island, where there is a need to monitor impacts on flora and fauna health in further studies. It is also noted that fishes can be sensitive sentinel species of aquatic ecosystem health.
Vibrio parahaemolyticus isolated from live shellfish marketed in Korea: antibiotic and heavy metal resistance
Authors:   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Seowon-gu, Cheongju 28644, Republic of Korea, Wickramanayake Masimbule Vidanalage Kasun Sameera , Majeed Sana ,   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Seowon-gu, Cheongju 28644, Republic of Korea, Kumarage Prasanga Madhushani ,   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Seowon-gu, Cheongju 28644, Republic of Korea, Heo Gang-Joon ,   Laboratory of Aquatic Animal Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Seowon-gu, Cheongju 28644, Republic of Korea
Published: November 2024

This study examined the antibiotic and heavy metal resistance properties in Vibrio parahaemolyticus isolated from Korea's five most popular shellfish. Thirty-four V. parahaemolyticus isolates were isolated by conducting biochemical tests and PCR. Isolation frequencies were 4 (cockles), 2 (scallops), 2 (mussels), 1 (Pacific abalone), and 25 (white-leg shrimp). The disc diffusion method was employed to detect antibiotic resistance. All isolates were resistant to ampicillin. Piperacillin, colistin, and vancomycin resistance were detected in 82%, 68%, and 50% of the isolates, respectively. Thirty-two isolates were multidrug resistant [Multiple Antibiotic Resistance (MAR) index ≥0.2]. β-lactam resistant blaSHV gene was the most prevalent gene detected in 68% of the isolates in PCR assays. In addition, blaCTX, aac(6’)-Ib, and blsTEM were detected in 21%, 44%, and 6% of the isolates, respectively. Phenotypic resistance to Pb, Cd, and Cu was detected in 25, 4, and 3 isolates, respectively in broth dilution test. CzcA gene was the prevalent detected in 16 isolates, followed by CopA and merA genes detected in 11 and 7 isolates, respectively. The findings of this study suggest that live shellfish marketed in Korea are a potential source of antibiotic-resistant V. parahaemolyticus.
Comprehensive review on prevalence of caseous lymphadenitis (CLA) in dairy goats: A systematic review and meta-analysis
Authors:   School of Animal Science, Aquatic Science and Environment, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Besut Campus, 22200 Besut, Terengganu, Malaysia, Mustaffa Nik Danial Asyraf Nik , Hian Chai Min ,   School of Animal Science, Aquatic Science and Environment, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Besut Campus, 22200 Besut, Terengganu, Malaysia, Al-Rashdan Yazan ,   School of Pharmacy, Amman Arab University, Amman 11953, Jordan, Mahmood Al-Jaff Khalid ,   School of Pharmacy, Amman Arab University, Amman 11953, Jordan, Ghazali Mohd Faizal ,   School of Animal Science, Aquatic Science and Environment, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Besut Campus, 22200 Besut, Terengganu, Malaysia, Ibrahim Noor Syaheera ,   School of Animal Science, Aquatic Science and Environment, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Besut Campus, 22200 Besut, Terengganu, Malaysia
Published: November 2024

Caseous lymphadenitis (CLA) presents a significant challenge to the dairy goat industry worldwide, negatively affecting animal health, productivity, and economic sustainability. It is a disease caused by Corynebacterium pseudotuberculosis, and its symptoms include the development of abscesses in lymph nodes and other organs. Generally, animals affected by CLA experience reduced milk output, reproductive problems, and higher morbidity and death rates. Furthermore, CLA could harm the well-being of animals by causing pain, discomfort, and disruption of normal behaviours. This review aims to determine the prevalence of CLA cases affecting dairy goats, map the geographical distribution of the disease in dairy goat herds throughout different locations, determine hotspots of CLA incidence and comprehend regional differences. Additionally, the study included relevant information on CLA prevalence in Asia. This comprehensive review is expected to help develop educational strategies for CLA prevention and control among dairy goat farmers. Moreover, an assessment of the economic impact of CLA in dairy goat operations on a global scale was performed. The losses associated with CLA are reduced milk production, lower meat yield, and increased veterinary costs. Besides, the variability of clinical presentation and the limits of conventional diagnostic methods make diagnosing CLA in dairy goats difficult. However, new developments in diagnostics, such as serological testing and polymerase chain reaction (PCR) assays, present chances for early detection and targeted control strategies. Examples of management strategies for CLA in dairy goat herds include vaccination, strict biosecurity protocols, and targeted treatment of infected animals. To surmise, the dairy goat industry can strive to mitigate the effects of CLA and maintain the well-being of dairy goat populations by tackling these challenges and executing comprehensive management strategies.
Nasal cavity fungus ball discovered accidentally: A case report
Authors: Lee Dae-Neung , Lee Dong Hoon , Lim Sang Chul
Published: November 2024

BACKGROUND

Fungal balls within the nasal cavity are an exceedingly rare clinical entity, typically presenting with nonspecific symptoms or being identified incidentally.

CASE SUMMARY

This report presents an incidental discovery of a fungal ball in the nasal cavity during routine imaging, with no associated clinical symptoms.

CONCLUSION

This case underscores the importance of considering the possibility of asymptomatic presentations of nasal fungal balls, which may be detected incidentally during imaging evaluations.
Ultrasound features of congenital cytomegalovirus infection in the first trimester: A case report
Authors: Chen Xiao-Li , Zhang Li-Qiang , Bai Li-Li
Published: November 2024

BACKGROUND

Congenital cytomegalovirus (CMV) infection represents a significant public health concern as the most prevalent viral infection in newborns, potentially leading to severe neurological and developmental complications. The majority of cases are asymptomatic and remain undetected during pregnancy due to the absence of effective screening methods.

CASE SUMMARY

A 27-year-old primigravida presented for early pregnancy ultrasound, which revealed an atypical finding: A normal anechoic thalamus appearing hyperechoic on the mid-sagittal view of the fetal head. Subsequent ultrasound examinations during mid and late gestation demonstrated classic intracranial features suggestive of congenital CMV infection. Chromosomal karyotyping and microarray analysis of the fetus yielded no significant abnormalities. Following comprehensive prenatal counseling regarding potential adverse fetal outcomes, the patient elected to continue her pregnancy. She ultimately underwent cesarean delivery at 42 weeks gestation at another facility, resulting in the birth of a female neonate. At five months of age, the infant presented with epilepsy and significant growth and developmental delays.

CONCLUSION

Congenital CMV infection occurs during the first trimester may manifest as hyperechoic thalamus which can be revealed by ultrasound in the mid-saggital view of the fetal head. Future research should investigate the correlation between echogenic thalamus and developmental outcomes, as well as explore early screening techniques for suspected congenital CMV infection cases.
When spiders take over: the expulsion of giant Amazonian ants from their nest
Authors: Oliveira Matheus Silva , Silva Edison Fernandes , Santos Ricardo Rodrigues , Lima Fabrícia Maria Sousa
Published: November 2024

Spiders have been documented using nests of various ant species. In this study, we recorded the non-harmonious use of a nest and the expulsion of giant Amazonian ants from their nest by a Diplura spider. Both species inhabit South American forests, including the Amazon rainforest and Cerrado. This event took place in the northern Cerrado of Brazil during the rainy season. The expropriation process lasted 13 days, beginning with the simultaneous occupation of the anthill and culminating in the complete eviction of the ants. Over the last two days, we observed intense ant activity at a second entrance to the anthill and the construction of a new nest. We propose that the funnel-web spider was using the ant nest as shelter. However, the simultaneous coexistence may have been limited due to the spider web blocking an entrance and dietary overlap leading to competitive exclusion.
Can the speed of information dissemination exceed the speed of light?
Authors: Wan Chuyi
Published: November 2024

In the double-slit interference experiment with light, once one of the slits is instantaneously closed, the point H on the screen directly opposite the other slit will experience a change in the intensity of light at that point. Moreover, the time it takes for the intensity of light at point H to change after the slit is closed is shorter than the time it takes for light from the slit to reach point H. This indicates that information is transmitted from the slit to point H on the screen at a speed faster than the speed of light c. This does not violate Relativity, as it does not conflict with the Principle of Constancy of Light Velocity. Information is transmitted at varying speeds within the wave packet. In the direction parallel to the propagation of the photons, the speed of information transmission matches c. However, in other directions, the speed of information transmission can exceed c. And according to the inference, it appears that causality is not an immutable law of nature. Causality is not easily overturned at the macro level, while it is not so at the quantum level.
Two-dimensional fetal speckle tracking; a learning curve study for offline strain analysis
Authors: de Vet Chantelle M. , Nichting Thomas J. , Fransen Annemarie F. , van der Woude Daisy A. A. , van der Ven Myrthe , Post Richard A. J. , van Lier Zoé , Oei S. Guid , van Oostrum Noortje H. M. , van Laar Judith O. E. H.
Published: November 2024

Objectives

Two-dimensional speckle tracking (2D-STE) strain analysis holds promise for assessing fetal cardiac function. Understand the learning curve before introducing 2D-STE into obstetrics is crucial. This study examined the learning curve for offline analysis of fetal left (LV) and right ventricular (RV) global longitudinal strain (GLS) using 2D-STE.

Methods

After 2D-STE training, three trainees (Maternal-Fetal Medicine fellow, OBGYN resident and medical student) analyzed 100 fetal heart clips using 2D-STE to calculate LV- and RV-GLS. Intra-class correlation coefficients (ICC) and Bland-Altman plots were compared GLS values across four sets of 25 clips for each trainee against the expert. Repeated measurements analysis compared GLS score differences between expert and trainees over time and among trainees, adjusting p-values with a Bonferroni correction.

Results

LV-GLS consistency evolved from poor-to-moderate during the first 50 measurements to moderate-to-good during the second 50 for all trainees. RV-GLS consistency evolved from poor-to-moderate during the first 75 measurements to moderate-to-good during the final 25 measurements for the fellow and resident. The student’s RV-GLS consistency was poor during the first 25 measurements, moderate-to good during the second 25 measurements and again poor-to-moderate during the final 50 measurements. Repeated measurements analysis showed a significant decrease in variability of the LV- and RV-GLS score differences between the expert and trainees over time (padj<0.001), which was not significantly different between trainees. Moreover, the mean of those differences were significantly different for all trainees for LV-GLS (padj<0.001) and RV-GLS (padj = 0.029), and did significantly change over time for RV-GLS (padj<0.001) but not for LV-GLS.

Conclusions

A clear learning effect was observed by the significant decrease in variability of the difference in the score between the expert and trainees over time. The consistency of fetal GLS analysis with 2D-STE was generally found to be moderate to good after 100 measurements in trainees.
The relative importance of herbicide use for conservation tillage adoption by U.S. corn and soybean producers
Authors: Dong Fengxia , Dodson Laura , Nemec Boehm Rebecca , Douglass Cameron , Ranville Michelle , Olver Ryan
Published: November 2024

Herbicide use is widespread in agricultural production to control weeds prior to and after planting and to “burndown” weeds in the spring for conservation tillage. Whether conservation tillage adoption leads to higher herbicide usage has been a question of policy relevance for decades in the United States. Older U.S. studies using standard statistical and economic techniques have not consistently demonstrated higher herbicide usage levels among producers practicing conservation tillage, but these studies did not fully account for other practices, economic, or agronomic factors. To provide a more timely and comprehensive understanding of the importance of herbicides to conservation tillage, this study achieves two objectives with the most recent, nationally representative data from the US Department of Agriculture. First, it describes trends and compares conservation tillage and herbicide usage among field corn and soybean producers, similar to previous studies using standard economic techniques. Second, a Classification and Regression Tree (CART) model is employed—a novel methodology relative to previous studies that offers distinct advantages over traditional regression modeling—to evaluate the importance of herbicide use for conservation tillage adoption while accounting for other factors. Pairwise mean comparisons for field corn and soybeans indicated that herbicide usage pre-emergence was significantly higher with conservation tillage, but there was no consistent, significant differences in herbicide usage post-emergence. The CART analysis (with prediction accuracy ranging from 68–72%) also showed that pre-emergent use of glyphosate was the strongest predictor (with predicted probabilities from 0.83–0.86) of conservation tillage for field corn in 2016 and soybeans in 2018. Other factors such as the use of crop rotations, highly erodible land, region, and farm size were also strong predictors of conservation tillage. These findings highlight the importance and complexity of herbicide use in the adoption of conservation tillage for U.S. field corn and soybeans.
“Developing the tool SDM:KOMPASS. Supporting shared decision making implementation processes”
Authors: Lund Lea , Hansen Dorte Gilså , Korsbek Lisa , Christiansen Mette , Steffensen Karina Dahl , Olling Karina
Published: November 2024

Shared decision-making (SDM) involves patients in choosing their treatment or care options. SDM enhances patient engagement and treatment satisfaction. SDM has proved difficult to implement and sustain in routine clinical practice, hence a supportive tool is needed. This quality improvement study focuses on the development of a generic tool, labeled SDM:KOMPASS, which is intended to support hospital settings by facilitating the visualization of their formative progress and the setting of goals for the SDM implementation into routine clinical practice. The main objective of the present paper is to describe the development of this generic tool. A six-step development process was performed to develop a tool and investigate the tool’s overall perceived usability. Qualitative methods, such as observations, individual and focus group interviews, provided insights. A 10-item quantitative survey gauged informants’ immediate attitudes towards the tool. Purposefully sampled informants (N = 20), including healthcare professionals and patients, contributed diverse perspectives regarding; 1) The tool’s readability and clarity, 2) the construct’s domains and content, and 3) the tool’s perceived usability. In alignment with real-world challenges, SDM:KOMPASS emerges as a potentially valuable resource for healthcare organizations embedding SDM. The six-step development process revealed how the tool SDM:KOMPASS has potential to enhance SDM implementation’s manageability, goal-setting, and focus. Professionals engaged in strategic implementation within somatic and mental hospital departments find the tool potentially beneficial and feasible. The tool shows promise and usability but requires careful attention due to its comprehensiveness. The next step is to alpha test the tool in clinical practice.
Teaching analysis of fortified monuments in a time of remote learning
Authors: Tikhonova Olha , Remeshylo-Rybchynska Oresta
Published: November 2024

First COVID-19 then the war in Ukraine forced educational institutions to adapt to online and hybrid teaching methods in new realms. Despite the challenges presented by this, some educators have found innovative ways to teach in hybrid mode, such as using new technologies or creative teaching methods. This article shows the method used by Olha Tikhonova and Oresta Remeshylo-Rybchynska to engage students in difficult situations with different kinds of restrictions and challenges, both during the COVID-19 restrictions and then after Russia’s invasion of Ukraine from 24 February 2022. The method is rooted in Olha Tikhonova’s comprehensive approach to analyzing case studies focused on castles, and the teaching methodology is built around this approach. The method is suitable for use in a partially or entirely virtual teaching environment. It is easily adaptable to interactive communication with participants through web meetings.
INCIDENCE OF COEXISTENCE OF FIBROID WITH PREGNANCY

AMONG WOMEN USING PORT HARCOURT AS CASE STUDY
Authors: Chukwuemeka Chinedum
Published: November 2024

ABSTRACT

Visualization 1: Uterine fibroids also known as leiomyoma are benign smooth muscle tumors of the uterus, they do not metastasize (invade neighbouring healthy tissues) and are non-cancerous. The study aimed to determine the incidence of coexistence of fibroid with pregnancy among women in Port Harcourt, Rivers State, Nigeria. To execute this work a retrospective approach was used in which case files of women with coexisting fibroid with pregnancy from 2012-2016 were retrieved and reviewed from the University of Port Harcourt Teaching Hospital and grouped into age of the women, the year case was reported and type of fibroid that coexisted. Also, a descriptive survey with a structured questionnaire was distributed to women in Portharourt. 322 data were collected and analyzed using simple arithmetic tools (percentage, mean, median, variance, standard deviation) and a t-test was used to test for hypothesis. The results were presented in tables, pie, and bar charts. It was observed that the incidence rate of coexisting fibroid with pregnancy among women in Portharcourt was 0.08%. The highest incidence rate was recorded in 2016 (32.92%) and the lowest was in 2013 (11.18%) it increased in 2014(16.77%) and further in 2015(22.98%) and then highest in 2016. It was observed that most women who develop coexisting fibroid with pregnancy are between ages 35-39(45.96%) and at least ages 25-29(16.46%). The mean age of the women is 34.21. The most common type of fibroid that occurred was the intramural type of fibroid (39%) and the least was the cervical one (4%). It can be concluded that based on findings from the study, the incidence of coexistence of fibroid among women in PortHarcourt is on the rise, hence health providers should take note and create awareness programs to educate women.
Současné pohledy na kategorii pohoda (well-being)
Authors: Mareš Jiří
Published: November 2024

Přehledová studie se věnuje pojmu, jenž vzbuzuje v posledních desetiletích zvýšený zájem odborníků z různých oborů, třebaže jeho základy položili filozofové už v antickém Řecku (viz dva základní přístupy – hedonismus a eudaimonismus). Navíc jde o pojem, pro nějž se obtížně hledá český ekvivalent. Mnozí čeští autoři tento pojem nepřekládají a pracují s celosvětově používaným anglickým termínem well-being. Jiná skupina českých autorů pracuje s termínem pohoda či osobní pohoda. Výklad celé problematiky je rozdělen do osmi částí. První část přibližuje staletou historii pojmu pohoda (well-being) a jeho proměny od antiky až po dnešek. Druhá část shrnuje současné snahy o definování pojmu pohoda a upozorňuje, že odborníci zatím nedospěli ke konsenzu. Třetí část nabízí přehled celého spektra teorií pohody a snaží se vysvětlit, z čeho vycházejí, na co kladou důraz a jak se dají využít. Čtvrtá část je zajímavá tím, že ukazuje, jak se jednotlivé vědní obory navzájem odlišují v chápání pohody a v práci s ní. Pro ilustraci byly vybrány tyto obory: medicína, pedagogika, psychologie, sociologie a nejnovější trend – multidisciplinární přístup. Pátá část přehledové studie prezentuje rozdílné typy pohody, které se v zahraniční odborné literatuře objevují. Naše analýza identifikovala celkem 30 různých typů pohody. Šestá část výkladu se soustřeďuje na diagnostikování pohody. Nabízí soubor 21 dotazníků zjišťujících míru pohody u dětí, adolescentů i dospělých osob. Sedmá část si zvolila téma, které zajímá širokou veřejnost, neboť se zamýšlí nad současnými poznatky o pohodě a nepohodě v prostředí školy. Poslední, osmá část přehledové studie nabízí pohled na intervence, které se snaží zlepšovat úroveň pohody u dětí a adolescentů.
PERMA5 – důkazy podložený rámec podpory well-beingu zaměstnanců vysokých škol
Authors: Kočí Jana
Published: November 2024

Zabývání se otázkami duševního zdraví mezi akademickými profesionály a personálem univerzit vyžaduje nasazení pozitivní psychologie a iniciativ podporujících pozitivní vzdělávání a pozitivního zdraví. Tento výzkumný projekt se soustředí na validaci škály The Employee Well-being Scale na českých univerzitách pro budoucí národní hodnocení s cílem zhodnotit well-being zaměstnanců univerzit a podpořit navrhování efektivních intervencí pro zlepšení bio-psycho-sociálního zdraví akademického personálu na základě výsledků hodnocení. Vycházejíc z nové teorie well-beingu PERMA5, která nově zahrnuje autenticitu jako klíčový stavební prvek, tento výzkumný projekt prezentuje komplexní rámec pro podporu well-beingu v akademickém prostředí. Škála The Employee Well-being Scale obsahuje 78 podkategorií hodnotících well-being zaměstnanců univerzit prostřednictvím mechanismu sebehodnocení na škále 0 (nejsem spokojený/á) – 10 (jsem absolutně spokojený/á). Výzkumný projekt si klade za cíl podpořit iniciativy v oblasti well-beingu ve vysokém školství v České republice a pomoci systematicky měřit well-being zaměstnanců univerzit po celém světě, přičemž přispívá k celkovému zlepšení kvality života akademických pracovníků.
‘Detestable Slaves of the Devil’: Religion as the ‘Third Pillar’ of the Civilizing Process
Authors: Císař Brown Lucy
Published: November 2024

Utilising the early modern witchcraft prosecutions as historical evidence, this article proposes a reconfiguration of Norbert Elias’ theory of The Civilizing Process to include ‘religious de-centralisation’ as a necessary ‘third pillar’ within long-term European development. It is argued that, given the significance of the medieval church and the threat to monarchical power posed by that same institution, decentralising organised religion from the functioning of the state was required in order to allow state formation to proceed. This is evidenced by the early modern recategorization of ‘magic’ as witchcraft and the resulting extension of state jurisdiction into the prosecution of witches to the disadvantage of the church courts.
Posun interpretačních rámcov problematiky dejin motorizmu v českej a slovenskej historiografii
Authors: Jančura Mikuláš
Published: November 2024

The phenomenon of motoring represents one of the most significant developments of the 20th century. As a research challenge for historians, it offers a wealth of potential avenues for investigation. The automobile has been shaped by dynamic interactions with broader economic, social, and cultural structures. In the historical sciences in the Czech Republic and Slovakia, motoring has been a marginalized subject for an extended period. At the outset, Czech historiography commenced an investigation into the phenomenon in question. Prior to 1989, however, it was perceived primarily as a technical artefact with its own internal genesis. Over time, the prevailing trends shifted in favour of a more comprehensive integration of the motoring sector within broader socioeconomic, cultural, legislative and political structures. In Slovakia, historical scholarship has gradually begun to address these trends, yet the research into this particular issue remains the exclusive domain of a relatively limited number of scholars. Consequently, a considerable imbalance existed between Czech and Slovak historiography, and this remains the case to this day. The objective of this study is to analyse the initial state and the subsequent shift in the interpretive frameworks of research into the history of motoring in Czech and Slovak historiography. Another objective is to identify and illustrate the aforementioned shifts in the perception and interpretation of motoring, utilising illustrative examples of key works in the Czech-Slovak comparative context.
Circulating Endothelial Cells and Circulating Endothelial Progenitors in Kidney Disease – Victims, Witnesses, or Accomplices?
Authors: Závada Jakub , Kideryová L. , Pytlík R. , Tesař V.
Published: November 2024

Nephrologists deal with a host of pathologic conditions involving renal and systemic endothelium. Both in native and transplanted kidneys, often the insult to the renal endothelium initiates the pathogenic process ultimately leading to the loss of organ function. Also, systemic atherosclerosis is accelerated in patients with renal dysfunction. In this review we would like to cover the possible role of CECs and their counterparts - circulating EPCs in the pathogenesis of endothelial dysfunction associated with chronic renal failure, ANCA-associated vasculitis, and progression of chronic renal disease.
Az orosz hatalmi ambíciók múltja és jelene Afrikában
Authors: Piller Mátyás Mihály
Published: November 2024

Korunk változó geopolitikai helyzetében kiemelten fontos megértenünk egyes nemzetközi folyamatok működését, így azt is, hogy egy-egy jelenleg is zajló konfliktus gyökerei hol erednek és milyen hatások következtében szöktek szárba. Oroszország és Afrika kapcsolata hosszú múltú, ám nem eleget tárgyalt téma, mely napjainkban ismét aktuálissá vált.  A formális és az informális orosz Afrika-politika hatásai 2024-ben jobban érződnek, mint néhány évtizede, és az orosz–ukrán háború következtében a nyugati világ is odafigyel a fejleményekre. Legyen szó akár az afrikai államok belpolitikai helyzetéről, a migráció hozzánk is elérő hatásairól vagy a kontinens élelmiszerellátásáról, Afrika újra és újra megjelenik a sajtóban, bemutatva a globális interdependencia kiterjedtségét és fokát.
Cikkemben igyekszem feltárni az orosz expanziós politika kezdeti tapogatózásait és fejlődését Afrikában, illetve bemutatni a Szovjetunió bukásától napjainkig terjedő időszakot e kapcsolatok rendszerében. Az összeomló Szovjetunió már bevett és újszerű tapogatózásait a lehető leghatékonyabban kívánom áttekinteni és a megfigyelt minták alapján konklúziót levonni.
A szomáliai keresztényüldözés társadalmi, közigazgatási és vallási aspektusai
Authors: Mészáros Márta
Published: November 2024

A keresztényüldözés a régmúltba visszatekintő gyökerekkel rendelkezik, nemcsak Európában, de világszerte. Az Open Doors International adatai szerint 2023-ban 4998 keresztény ember vesztette életét vallási okokból. A Magyar Nemzeti Katonai Stratégia az etnikai konfliktusokat a tömeges illegális migráció egyik fő okaként nevezi meg. Honnan ered a keresztények elleni agresszió és miért nem enyhül a feszültség Szomáliában? Miért Szomália a második legveszélyesebb hely egy keresztény számára? Jelen tanulmány célja, hogy a szomáliai keresztényüldözés jelenlegi helyzetére fókuszáljon, melynek fő forrása az ország morális válságában keresendő. A tanulmány nem csupán a társadalom keresztényekkel szembeni hozzáállását kívánja bemutatni, hanem azokat a politikai és közigazgatási intézkedéseket is, amelyek akadályozzák a válság megoldását.
Editorial
Authors: Cerqueira Fábio Vergara
Published: November 2024

Neste segundo número do Cadernos do LEPAARQ, que ora lançamos, concluímos a etapa inicial de estruturação do periódico, garantindo, no primeiro ano, a periodicidade semestral, regra que deverá ser mantida ao longo dos próximos volumes.
A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line
Authors: Heydarzadeh Shabnam , Moshtaghie Ali Asghar , Daneshpour Maryam , Hedayati Mehdi
Published: November 2024

Aims and background

Curcumin’s function in affecting cancer metabolic reprogramming remains poorly understood. Herein, we aimed to elucidate a novel link between curcumin and the glucose uptake metabolism and the status of glucose transporters (GLUTs) in the SW1736 cell line derived from anaplastic thyroid cancer.

Materials and methods

The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test and flow cytometry were employed to test cell viability and cell death. For glucose uptake detection, the ‘glucose oxidase/peroxidase 4-aminoantipyrine’ enzymatic colorimetric assay was applied to measure the direct glucose levels inside the cells. Determination of GLUT1 and GLUT3 mRNA and protein expression in SW1736 cells was performed by qRT-PCR and western blotting. In addition, the scratch wound healing assay was conducted for cell migration.

Results

The data indicated that curcumin-induced cell death is independent of apoptosis in this type of thyroid cancer cell line. Furthermore, significantly reduced GLUT1 and GLUT3 expression was observed after treatment with curcumin, resulting in the inhibition of glucose uptake (P < 0.05). Scratch assay indicated the inhibition of cell migration in SW1736 cells treated with curcumin (P < 0.05).

Conclusion

It can be concluded that GLUTs, as metabolic targets, can be blocked specifically by curcumin for thyroid cancer prevention. Curcumin, as a promising anti-cancer agent, inhibits the growth of SW1736 anaplastic thyroid cancer cells by regulating the glucose uptake pathway and cell death. Altogether, these results suggest that the glucose pathway may be an essential target for therapeutic intervention to sensitize tumor cells to the cell death process by inhibition of glucose transporters.

Statement of translational relevance

As described in our previously published article, ‘Regulators of glucose uptake in thyroid cancer cell lines’, non-oncogene addiction is one of the recent principles of cancer therapy. Moreover, herein, for the first time, we decided to investigate the anti-thyroid cancer effects of a bioactive phytochemical and establish a signaling link between curcumin and the glucose uptake metabolism of anaplastic thyroid cancer cells. This title covers the entire range of the biological sciences, and we attempt to fill the gaps between cell biology, medicine, cancer and plant knowledge. The influence of cancer on human society is indescribable. Human studies are often contradictory around the effects of polyphenols against cancer. We believe that it is important to draw boundaries between the usages of polyphenols in cancer prevention versus cancer treatment. We anticipate that this study’s findings will contribute to a better understanding of the mechanism underlying curcumin’s anti-cancer properties, providing a theoretical foundation for the future clinical application of curcumin-related medications.
In the Aftermath of the Pandemic: A Jobs-to-be-done Perspective on Stationary Retailing
Authors: Rese Alexandra , Wolfschmidt Daniela
Published: November 2024

This paper employs the Jobs-to-be-done (JTBD) theory to investigate how the pandemic has changed, for the long term, customer behavior when visiting the city center and which “jobs to be done” (abbreviated: jobs) customers now pursue during their visits. Using a literature review, we identified several direct pandemic-induced changes in customer behavior. To test the long-term nature of these behavioral changes and to explore the JTBD framework, we conducted a qualitative empirical study involving 18 German respondents of different gender and age profiles. We were able to identify several functional, emotional, and social jobs in the context of a city center visit. The last two job types are more important for women. While some of the pandemic-related behavioral changes became permanent, such as increased online shopping, others proved to be temporary. The differences in the customer groups can be employed to improve the city center by highlighting the benefits of product inspection and immediate availability and the hedonically valuable shopping experience.
Reciprocal Effects of Cognitive, Affective, and Social Customer Experience on Customer Loyalty and Word-of-Mouth in Omnichannel Fashion Retailing
Authors: Fränzel Nils , Swoboda Bernhard
Published: November 2024

Although the cognitive dimension of customer experience (CX) affects the affective or social dimensions of CX and vice versa in consumers’ thoughts and behavior, our understanding of this reciprocity is limited. The authors fill this gap by applying categorization theory rationales to analyze whether reciprocity exists among important CX dimensions in consumer shopping at omnichannel retailers and how it affects consumer loyalty versus word-of-mouth. They analyze longitudinal data from 528 consumer evaluations of leading fashion retailers in three waves via cross-lagged panel models. The results indicate that the cognitive CX dimension increases the affective and social dimensions and vice versa but to different extents. The reciprocal effects of the CX dimensions are different for consumer loyalty and word-of-mouth, and the results differ from those of a nonreciprocal study. These findings have direct implications for managers interested in understanding how the reciprocity of CX dimensions affects consumer behavior.
Sposoby oznakowania leków stosowanych do znieczulenia w szpitalach w Polsce – badania pilotażowe
Authors: Mędrzycka-Dąbrowska Wioletta , Kwiecień-Jaguś Katarzyna
Published: November 2024

Wstęp W 2010 r. przewodniczący krajowych towarzystw anestezjologicznych podpisali Deklarację Helsińską w sprawie bezpieczeństwa pacjenta w anestezjologii, której jednym z głównych zaleceń jest prawidłowe oznakowanie strzykawek. Cel Celem badań była analiza sposobów etykietowania strzykawek przez pielęgniarki anestezjologiczne pracujące na sali operacyjnej do przygotowania leków stosowanych podczas znieczulenia. Materiał i metody Kwestionariusz ankiety został opracowany w oparciu o dostępne zalecenia i wytyczne. W badaniu wzięły udział pielęgniarki/pielęgniarze oddziałowi lub koordynujący obszarem anestezjologii. Udział w badaniu był dobrowolny oraz anonimowy. Zbieranie wypełnionych kwestionariuszy trwało 3 miesiące. Wszystkie obliczenia statystyczne przeprowadzono przy użyciu pakietu statystycznego IBM SPSS 23 i arkusza kalkulacyjnego Excel 2013. We wszystkich obliczeniach przyjęto poziom istotności p<0,05. Wyniki Respondenci pochodzili z 349 szpitali z całej Polski, co odpowiadało liczbie oddziałów anestezjologii. W projekcie wzięły udział: 34 pielęgniarki ze szpitala klinicznego, 141 pielęgniarek ze szpitala wojewódzkiego i 174 pielęgniarki ze szpitala miejskiego. Analiza statystyczna nie wykazała istotnych różnic statystycznych pomiędzy procedurami oznakowania leków w różnych szpitalach. Statystyki potwierdziły, że stosowanie wodoodpornych markerów było istotnie częstszym sposobem oznakowania strzykawek w szpitalach miejskich i wojewódzkich niż w szpitalach klinicznych, a odręczne opisy na opakowaniach strzykawek były częstsze w szpitalach wojewódzkich niż w szpitalach klinicznych (χ2(8)=17,96; p=0,021). Wnioski Istniejące systemy oznakowania leków stosowanych w anestezjologii w Polsce nie są bezpieczne. Lekarze i pielęgniarki anestezjologiczni/e przemieszczający/e się między szpitalami muszą pamiętać o różnorodności etykiet strzykawek, a także możliwych z tego powodu błędach i pomyłkach.