bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of Vitamin D with Obesity in Premenstrual Syndrome: A Study of Female Population of Hyderabad, Sindh
Authors: Naeem Aqsa , Bhatti Urooj , Batool Sarwat , Shaikh Khalida , . Arsalanuqaili , Rani Keenjher
Published: April 2023

Introduction/Objectives: The affiliation between decreased vitamin D and obesity is well built up. Females with Premenstrual Syndrome (PMS) are more prone to gain weight. Obese women's low calcifediol levels are impacted by diets and inactive lifestyles.The studyfocused to discover out the relationship between vitamin D and obesity in premenstrual syndrome females. Materials & Methods: Two hundred fifty (250) females between15-45 yearswith a history of PMS were selected from OPD-Gynecology, Liaquat University of Medical&Health Sciences (LUMHS), Jamshoro and Hyderabad in collaboration with Physiology Department LUMHS Jamshoro and samples were analyzed in Diagnostic and Research lab Hyderabad. Information was collected on marital status, vitamin D3 levels, PMS intensity, and BMI. The Chi-square test compared the vitamin D levels with BMI and PMS scores. Results: Mean age of the patients was 29.89±5.206 years. 64.8% of patients were married. 42.8% had normal weight and 40.8%were obese. 35.2% of patients had mild PMS scores and 36.4% had extreme PMS. 61.2% of patients had vitamin D lack with only 4.8% having adequate serum vitamin D levels. 22.8% of normal-weight patients had inadequate serum vitamin D levels. 35.6% of obese patients had vitamin insufficiency in their blood. The relationship between obesity and vitamin D levels was significant (P-value: 0.001). 18.8% of patients who had mild PMS scores had deficient serum vitamin D levels. The relationship between PMS scores and vitamin D levels was remarkable (P-value: 0.001). Conclusion: We found a significant, inverse relationship between vitamin D levels and BMI, showing that losing weight through vitamin D and calcium-enriched diets may result in typical vitamin D levels, and so PMS may be treated. Keywords: Vitamin D (Vit D),Premenstrual Syndrome, body-mass index(BMI)
Prevalence of Progression Toward Renal Calculi in Patients Suffering from Urinary Tract Infection: A Cross-Sectional Study
Authors: Ahmed Gilani Syed Waseem , Shaikh Aatif Hassan , Pirzada Abdul Jabbar , Khan Irfan Ullah
Published: April 2023

Objective: To assess the frequency of renal stones in the patient suffering from urinary tract infection (UTI) Study design: A cross-sectional study Place and Duration: This study was conducted at Northwest General Hospital Peshawar from June 2021 to June 2022 Methodology: A total of 115 patients with the symptoms of recurrent urinary tract infection were included in the study. Those patients who had a positive history of upper and lower urinary tract stones, renal tumors, already present renal calculi, and patients with renal failure, were not added to the present study. A specially designed proforma was filled out by all the patients so that the required data could be acquired and analyzed. Results: The mean age of the patients was 36.1±15.2 years ranging from 15 years to 60 years. Urinary tract infection was confirmed in 92 (80%) patients. The most prevalent organism detected on urine culture was E.Coli (29%). Some of the other organisms majorly detected were Proteus (18%), Pseudomonas (8%), Klebsiella (10%), and Staphylococcus aureus (4%). The renal stone disease was found in 18 (19.56%) patients out of which 12 (13.04%) were male and 6 (6.52%) were female. The mean age of the patients presented with renal stones was 32.65±15.3 years. The male-to-female ratio of the patients with renal stones was 1.5:1. Conclusion: A large number of patients with urinary tract infections can develop the renal stone disease. Certain microorganisms are significant in this progression and resulting in renal stones. Keywords:Urinary tract infection, renal stone disease, Microorganisms, E.Coli
Factors Affecting Non Compliance with Exclusive Breastfeeding Among Mothers: A Survey at District Hospital Dadu
Authors: Khalid Alma , Aman Suhail , Talreja Washdev , Jhatial Irfan , Hussain Wajid , Wadho Sasui , Shahani Muhammad Parial
Published: April 2023

Background: According to standard guideline for breastfeeding, t is mandatory to practice exclusive breastfeeding during the first six months of a baby's life to provide the finest physiological support for all neonates. In Pakistan there is visible underuse of exclusive breastfeeding among lactating mothers. This study aims to assess the variables affecting the non-compliance to exclusive breastfeeding among mothers at a district hospital in Pakistan. Materials and methods: A descriptive cross sectional study was conducted to in Pediatric OPD at the district hospital Dadu from January to June 2022, 162 breast feeding mothers were interviewed regarding their practice towards exclusive breast feeding. Results: We observed that only 29. 5% mothers practiced exclusive breast feeding. All the mothers in the study had a breastfeeding child. Most of the mothers in this study were aged between 20 to 40 years (62%). The most common reason for non-compliance with the exclusive breastfeeding was the use of formula milk by the mothers. Conclusion: Inclination to use formula milk, insufficient breast milk, early weaning and lack of the education among mothers were most common causes of non-compliance towards exclusive breastfeeding. Mass level health education for maternal and child health are recommended. Keywords Breast feeding, Exclusive breastfeeding, Neonate, Maternal factors,
Prevalence of Splenic Injury in the Blunt Abdomen Trauma: A Cross- Sectional Study
Authors: Arshad Rabia , Khan Aurangzeb , Bhatti Shaheen Gul , Mubashir Chandio Muhammad Ahmed , Khatti Shah Nawaz , Nasir Seema
Published: April 2023

Background: Blunt trauma to the abdomen most commonly leads to injury of the spleen. Patients usually presents with left hypochondriac pain or generalized abdominal pain which may radiate to the left shoulder. There can be associated left lower rib fractures. Diagnosis is made on contrast enhanced computed tomography (CT) of the abdomen. Surgical management is warranted in the cases according to AAST Grade of injury. Missed or delayed presentation of injury can lead to mortality hence careful evaluation of mode of injury, complete examination, appropriate investigation and monitoring are vital for patient management. Objective: The present study aims at the determination of incidence and causes of splenic injury after blunt trauma to the abdomen. Study design: A cross-sectional study Place and Duration: This study was conducted at Rawalpindi Medical University from November 2020 to November 2022 Methodology: A total of 195 patients were included in the study. The lowest age limit was 15 years and patients of both genders were considered. The patients with abdominal trauma were received in the emergency department. A detailed history of the event was taken from all the patients with simultaneous resuscitation. After that, a thorough clinical examination was performed on all the patients. The patients were sent for a FAST SCAN and CCET abdomen to diagnose and assess the extent of the injury. The type of trauma that lead to the injury of the spleen, such as road traffic accident (RTA), assault, and fall from height was recorded of each patient. Patients with AAST grade I and II were managed conservatively except in cases where exploration was required for concomitant abdominal injuries however patients with Grade III, IV and V underwent exploration, spleenoraphy or splenectomy respectivelyThe data was collected and analyzed in the IBM SPSS version 26. Result: A total of 195 patients were studied, out of which 48 (24.61%) were female and 147 (75.38%) were male. The mean age of the patients was 30.45±2.12 years. Overall 12 (6.15%) were detected with splenic injury. A total of 5 (41.67%) had an RTA, 4 (33.33%) had a fall from height, 2 (16.67%) assault, and 1 (8.33%) had sports injury. Conclusion: The most common type of blunt trauma to the abdomen which resulted in a splenic injury was road traffic accidents followed by fall from height. Early diagnosis is helpful in the proper management of the patient and increasing the survival rate. Keywords: Splenic injury, road traffic accident, blunt trauma
Transformation of observation unit to address higher acuity patients and increase bed capacity during a Covid-19 surge
Authors: Vera Jennifer , James LaDuska , Rose Alexis
Published: April 2023

A Magnet®-designated acute care community hospital in Southeast Texas experienced a COVID-19 surge during the summer of 2020 that increased the acuity of admitted patients. The critical care, intermediate care, and COVID-19 units were consistently at capacity. These beds were no longer considered an available resource, but their need continued to grow. As hospital acuity increased, patients were placed in medical or surgical (medsurg) units when historically they may have been placed in a critical care unit. Hospital leadership determined that more space was needed to cohort COVID-19 patients, specifically those on high-flow oxygen. Given the decrease in observation status patients, an existing observation unit was converted into a high-flow oxygen unit using team nursing and personal protective equipment (PPE) zones. The successful transformation of the observation unit provided a guide on the cohorting of patients and team nursing approach for any future disease surges.
Basic Immunization Program Coverage of Minimum Service Standards (MSS) in Raja Aligas, Huta Bayu Raja District
Authors: Shofian Syarifuddin
Published: April 2023

Immunization is an effective way to provide immunity, especially to someone who is healthy, with the main goal of reducing morbidity and mortality due to various diseases that can be prevented by immunization. One of them is measles, which often attacks children under the age of five. The research objective was to determine the results of the basic immunization program coverage against the Minimum Immunization Service Standards. The research design used in this study is a descriptive study design. The number of samples in this study from the Raja Maligas  in Silakkidir Village, Huta Bayu Raja District, Simalungun Regency was 47 people. with the sampling technique in this study using total sampling. Data analysis used is descriptive analysis. The results of the research on immunization coverage at Raja Maligas  in Silakkidir Village showed that the majority of babies had received basic immunization HB 0, DPT/HB 1, DPT/HB 2, DPT/HB 3, POLIO 1, POLIO 2, POLIO 3 as many as 47 people (100% ) and a minority of infants received basic immunizations for BCG, POLIO 4, and MEASLES, respectively 95.7%, 97.9% and 95.7%. From the results of this study it is known that the coverage of the basic immunization program at the Raja Maligas  has reached the Immunization Minimum Service Standards (SPM) in accordance with those set by the Government. So it is recommended that immunization officers at the health center continue to provide complete basic immunization services to every baby before the age of 1 year.
Characterization of polyunsaturated fatty acids and antioxidant activity of Vitis vinifera L. (grape) seeds from the Ica Valley, Peru
Authors: Surco-Laos Felipe , Garcia Jorge A. , Bendezú María R. , Alvarado Angel T. , Laos-Anchante Doris , Valle-Campos Manuel , Panay-Centeno Juan F. , Palomino-Jhong Juan J. , Yarasca-Carlos Paulina Eliades , Muñoz Ana María , Bolarte-Arteaga Mario , Pineda Mario , Loja Berta
Published: April 2023

Context: In the Valley of Ica-Peru, the seeds of the fruit of Vitis vinifera L. (grape) are residues from the Pisco Industry, and due to their bioactive compounds, they can represent a new economic and sustainable activity for the population of the mentioned Valley. Aims: To characterize polyunsaturated fatty acids from the seeds of the fruit of Vitis vinifera L. (grape) from the Ica Valley, Peru and determine the antioxidant activity in vitro. Methods: The oil from five grape varieties (Quebranta, Moscatel, Torontel, Mollar, and Italia) was obtained by ethereal extraction with ultrasound. The profile of fatty acids was characterized by gas chromatography with a flame ionization detector (GC-FID). The total polyphenolic content was determined by the Folin-Ciocalteu method and antioxidant activity by two in vitro methods. Results: The values obtained from the 5 grape varieties are presented in a range: total polyphenolic content (TPC: 0.59-154 mg GAE/g); linoleic acid content (69.90-71.87%), oleic acid (18.35-19.90%) and others in a lower percentage (p>0.05). Antioxidant activity: DPPH IC50 38.30-48.43 µL; FRAP 0.49-0.77 μg TEAC/g. TPC/DPPH and TPC/FRAP were significantly different (p<0.05), except for the Mollar TPC/FRAP variety (p>0.05). Conclusions: The oils from the seeds of the Vitis vinifera fruit (grapes) that are residues from the production of Pisco present physicochemical characteristics of oils of high nutritional value with a predominance of polyunsaturated fatty acids and potential antioxidant activity.
الجهل باللغة واختلاف القراءات وأثرهما على الانحراف التفسيري
Authors: عبدالحسين جليل عبد الحسن  , أ.د. محمد محمود زوين
Published: April 2023

يهدف البحث إلى بيان خطورة الانحراف في التفسير وكيف بدأ ومتى بدأ وكيف كان لأئمة أهل البيت (عليهم السلام) دورٌ بارز في رد الكثير من الآراء التفسيرية المجانبة للصحة بطريقة نقدية, وباستدلالات  قائمة على  اصول التفسير الصحيح مع بيان تلك الأسباب, ومنها الجهل باللغة العربية وأساليبها, فالضعف في اللسان العربي والجهل بقواعده من النحو والاشتقاق والاعراب وعلم المعاني من أهم اسباب الانحراف في التفسير.

وأما اختلاف القراءات القرآنية فلها انعكاسات سلبية على فهم النص القرآني عِبرَ القراءات المخطوءة, وكيف أثرت في نشأة الانحرافات التفسيرية بما تحمله من اختلافات في الحركات واختلاف البناء والتقديم والتأخير والزيادة والنقصان, دون الرجوع إلى القرائن الأخرى التي يستعين بها المفسِّر للوصول إلى المعنى الصحيح .
AVALIAÇÃO DO CONHECIMENTO E DO ESTADO NUTRICIONAL DE PACIENTES COM CÂNCER EM UM HOSPITAL PÚBLICO DO INTERIOR PAULISTA
Authors: Santos Aparecida de Jesus Cipriano , Lima Erika Urias de , Amorim Michele Fernanda Costa de , Genaro Sandra Cristina
Published: April 2023

Weight loss in cancer occurs both through disease and treatment. The objective was to evaluate the nutritional knowledge of cancer patients and their nutritional status. This was an observational, descriptive study of 50 cancer patients, over 19 years old, admitted to a public hospital in the interior of São Paulo. Nutritional knowledge, anthropometric profile and weight loss were evaluated. For data analysis, the frequencies, mean and standard deviation of continuous variables were calculated and presented in the form of tables, charts and graphs of sectors. 44% of the patients had severe weight loss before the diagnosis of the disease until the moment of the research and a greater weight loss was evident in those patients who presented medium and low nutritional knowledge. It is necessary to creat nutritional education actions aimed at improving knowledge and eating behavior, in order to clarify doubts and improve their nutritional status.
COMPARAÇÃO DO USO DE IECA E BRA EM PACIENTES COM INSUFICIÊNCIA CARDÍACA – REVISÃO INTEGRATIVA
Authors: Pegoraro Cristiane Martinez Ruiz , Bifaroni Renata Mano Scatamburlo , Rezende Laura Emiliana , Pereira , Júlia Oliveira Mendes , Medeiros Anne Carolina Xavier , Silva Azania Mahim José Libanio da
Published: April 2023

Heart failure (HF) is an inability of the heart to surprise tissue metabolism. The Brazilian Society of Cardiology, in 2020, 100 thousand new public health diagnoses and a rate of 50 thousand citizens/year, configuring a public health problem. Therefore, compare the diligence of Angiotensin Converting Enzyme Inducers (ACEI) and Angiotensin Receptor Blockers (ARB) in HF, for results: clinical stability, hospitalizations and deaths. Searches of 1789 randomized clinical trials were carried out on the platforms: Cochrane, PubMed and LILACS, based on indexed descriptors, with the terms MESH/Decs, of which 8 were in full. Perindopril functional hospitalization (HR 0.928; P 0.033), mortality (HR 0.98; P 0.928) and class (P 0.030). Both enalapril and candesartan reduced deaths and hospitalizations. Discontinuation of ACEI/ARB increased 4-fold mortality in 180 days. Therefore, there is evidence of therapeutic equivalence among the drugs analyzed in the CI.
Breast Cancer in Brazil: Social Conditions and Access to Health Care
Authors: de Castro Maia Senna Mônica , Nunes de Oliveira Thaislayne , Louzada Carvalho Debora
Published: April 2023

Breast cancer is the most predominant type among Brazilian women, ranking second position within the causes of mortality in the female population. According to the National Cancer Institute (INCA) estimates, for each year of the triennium 2023–2025, 73.610 new cases are expected. Although it is not subject to primary prevention, breast cancer tends to have a satisfactory prognosis and greater chances of cure if identified early. The high mortality rates indicate, however, that access to early diagnosis and to treatments is a flawed aspect of the country. The chapter addresses the main social conditions that affect the high rates of morbidity and mortality, emphasizing aspects both related to the provision of health care services and some social characteristics of women that mark the inequalities which make health care difficult. It also discusses aspects related to health policies and access barriers toward breast cancer control.
Domestic Waste Management Strategy through Realization of School Waste Banks towards Students Scientific Behavior
Authors: Sutisno Aliet Noorhayati , Novianawati Noor , Hidayatullah Muhammad Arif Syarif
Published: April 2023

The inability to read the opportunities of the dilemma of the distribution of waste in the environment in relation to the needs of the educational transmission period in the post-pandemic era as it is today leads to our limitations in meeting the needs of educational efforts and strategies in various challenges of the times. This study aims to present educational transmission efforts and strategies for handling waste distribution in the post-pandemic era which is an innovative educational approach towards sustainable human and natural resource development based on an economic-socio-cultural basis. The method is descriptive quantitative that was conducted at one of the public schools elementary from  August until November of the 2021/2022 academic year. The sample is 150 students from 1, 2, and 3-grade elementary schools. The results found in the field are that through the realization of the school waste bank regarding the regulation of implementing waste sorting from home and then proceeding to deposit waste to the school waste bank this strategy initiates scientific practice towards the scientific behavior of students. The contribution of this research is instilling good behavior from an early age, and it is hoped that good habits will emerge and contribute to environmental sustainability.
Evaluation of Referral Ratios in Facing Universal Health Coverage in Primary Healthcare Centers
Authors: Nurfikri Ari , Roselina Elsa
Published: April 2023

Following the road map from the Social Security Agency for Health in the 2020-2025 period, a preventive approach is used for achieving universal health coverage. However, there are still disparities in the referral rate as an indicator of preventive efforts between cities and rural areas. The study aims to describe service referrals' achievements, the met capacity of human health resources, and the active participation of integrated health service posts for non-communicable diseases. The method used a quantitative approach. Research place in Cirebon City and Cirebon District, Indonesia. Referral rate data was collected in August-December 2019. The data on service capacities, health resources, and integrated health service participation was collected in August-December 2020. The result shows that the average referral rate in primary healthcare centers of Cirebon City was better than that of Cirebon District. The standard services in primary healthcare centers of Cirebon City were better than those in Cirebon District. The standard human resources in primary healthcare centers of Cirebon District were more qualified than those in Cirebon City. The active participation of integrated health service posts for non-communicable diseases in Cirebon City was better than in Cirebon District. The contribution of this article is to provide health care information about the evaluation of referral ratios in facing universal health coverage.
Development of horticulture extension support system for the small holder farmers: A case of Tanzania
Authors:   , Maginga Theofrida
Published: April 2023

Horticulture as part of agricultural sector plays the role for food security, economic growth and nutrition improvement in developing countries. It draws attention for most governments as the main source of employment. Following the governments’ recognition of agricultural extension as key facilitator for achieving high crop productivity and an enabler to knowledge resources, number of extension officers have been recruited to help farmers. However, these extension officers cannot reach every farmer due to lack of enough resources and cultural barriers. Consequently, uniform availability of clear information for vegetable cultivations, on crop requirements, climatic information, pests and diseases is a challenge. Meanwhile, there are number of extension support systems that do not meet all the requirements. On this study, a survey that included 145 small holder farmers and 30 agronomists from three regions located in three main horticultural zones in Tanzania was conducted. The data collected through questionnaires and interviews. The findings depicted that a significant number of farmers are not so familiar with ICT enabled horticulture extension support systems. The analysis results also indicated few technological systems that do not yet serve all the farmers. Therefore, in this study an ICT-enabled horticulture extension support system has been developed to help farmers make proper decisions on vegetable cropping systems. The application provides information such as best sowing period of the crop based on weather data in a particular location, crop harvest day, crop requirements, crop pests and disease. Accessibility of this information will help to improve vegetable crop productivity.
Tersingkir Karena Kusta
Authors: Nur Aziz Dian Andi
Published: April 2023

Penderita  kusta, termasuk  keluarganya menghadapai diskriminasi dari masyarakat, bahkan setelah dinyatakan sembuh  dari kusta. Sehingga, kusta bukan hanya urusan kesehatan. Diskriminasi dari  masyarakat muncul  karena  stigma  kusta.  Sebagian orang  meyakini  bahwa  kusta  mudah  menular,  turunan, dan  kutukan.  Keyakinan ini tertanam secara  mencalam. Artikel ini menggambarkan tentang perlindungan dan pemenuhan hak penderita atau orang yang pernah  mengalami  kusta termasuk keluarganya khususnya  hak pendidikan,  hak kesehatan, hak pekerja dan pekerjaan, kebebasan berpendapat, hak berorganisasi  dan berkumpul.
የቅማንት ማህበረሰብ ሀገረ-ሰባዊ ልምድና ቁሳዊ ባህል ጥቁምታዎች
Authors: Mekonen Teka
Published: April 2023

የቅማንት ማህበረሰብ ሀገረ-ሰባዊ ልምድና ቁሳዊ ባህል ጥቁምታዎች
PATTERNS OF CHANGE IN POPULATION, FARMLAND SIZE AND FOREST COVER IN SIGMO DISTRICT OF OROMIA REGION, ETHIOPIA
Authors: Getu Lemma  , Yechale Kebede  , Zenabu Alena
Published: April 2023

The world population is exceeding seven billion at the same time when resource limits and environmental degradation are becoming more apparent every day. This paper analyzes the nexus between population dynamics and forest degradation. The study quantified the effect of human population growth on rates of deforestation using GIS based information taken for 30 years (1985-2015) in Sigmo district, South Western Ethiopia. A mixed approach, comprising of both quantitative and qualitative methods, is used for the study. Descriptive statistical techniques such as frequencies and percentages are employed and presented in tables, graphs, charts, and satellite image maps. Inferential statistics such as, Pearson correlation coefficient are implemented to demonstrate the degree of association between the dependent (forest area and farmland size) and independent variables (population growth). The findings of the study revealed that the population of the study area has grown very rapidly (2.9% /year). The rapidly growing population adversely impacted the forest resource of the area in a way of agricultural land expansion, fuel wood consumption, settlement expansion, timber harvest for construction and commercial logging. Thus, between 1985 and 2015, forest cover of the study area got reduced nearly by half (48.8%) while farm lands expanded by about 124%. These, in turn, have resulted in soil erosion and loss of soil fertility, depletion of biodiversity, interruption of water flows, and the spread of desertification
Analisa Dan Perancangan Aplikas Penggajian Karyawan Dengan Metode Netto Berbasis Web Studi Kasus Indigo Production
Authors: Faizal Zuli  , Indrawan
Published: April 2023

Gaji merupakan imbalan atas jasa-jasa yang dilakukan oleh karyawan yang dilakukan perusahaan setiap bulan. Di era modern saat ini kemajuan teknologi dan ilmu pengetahuan merupakan bagian yang sangat penting dan sangat berpengaruh dalam perkembangan suatu organinasi. Pesatnya teknologi informasi telah merubah tata kerja disegala bidang menjadi lebih efisien, praktis danhandal dari waktu ke waktu. Analisan Perancangan Aplikasi Penggajian merupakan sistem yang dibangun untuk mempermudah pelaksanaan penggajian karyawan secara tepat dan akurat dengan mengkomputerisasikan keseluruhan maupun beberapa bagian dari proses penggajian tersebut disertai dengan pengendalian atau kontrol atas sistem komputerisasi. Dengan adanya aplikasi inibertujuan untuk memberikan kemudahan dalam mengontrol keseluruhan aktivitas karyawan dan mempermudah perusahaan dalam memproses gaji karyawan dengan cepat, tepat, dan efisien
IMPLEMENTASI SISTEM PENDUKUNG KEPUTUSAN PENENTUAN KELAYAKAN ROTASI KERJA KARYAWAN MENGGUNAKAN METODE SIMPLE ADDITIVE WEIGHTING
Authors: Muhammad Ridwan  , Istiqomah Sumadikarta
Published: April 2023

PT. Nutech Integrasi melakukan evaluasi terhadap karyawan setiap 6 bulan sekali, evaluasi tersebut berupa penilaian karyawan dan rotasi kerja berdasarkan hasil penilaian. Karena proses rotasi kerja karyawan yang berdasarkan penilaian dilakukan secara manual, maka ini menjadi kurang efektif. Maka dari itu solusi terbaik untuk menyelesaikan masalah diatas adalah dengan mengimplementasikan sistem pendukung keputusan menggunakan metode Simple Additive Weighting (SAW) untuk proses penilaian karyawannya, yang akan digunakan sebagai acuan proses rotasi kerja secara otomatis oleh sistem berdasarkan penilaian tersebut. Kriteria yang digunakan pada metode tersebut diantaranya Kedisiplinan, Kepribadian, Hasil Kerja, dan Kemampuan. Dengan adanya sistem tersebut maka dapat menghasilkan hasil penilaian karyawan serta hasil rotasi kerja karyawan secara otomatis berdasarkan penilaian tersebut sehingga diharapkan dapat mempermudah proses evaluasi yang dilakukan PT. Nutech Integrasi
SISTEM PERPUSTAKAAN BERBASIS WEB SMPN 226 JAKARTA DAN PENGOPTIMALAN PENCARIAN DENGAN NAIVEBAYES
Authors: Arip Rahman Hakim  , Achmad Udin Zailani
Published: April 2023

Perpustakaan adalah perpustakaan dikenal sebagai sebuah koleksi besar yang dibiayai dan dioperasikan oleh sebuah kota atau institusi. Demikian halnya di lembaga pendidikan formal seperti sekolah, perpustakaan merupakan sarana wajib yang harus ada.Tetapi tidak semua sekolah mempunyai senuah sistem informasi yang dapat menyimpan dan mencatat pengolahan data buku. Berdasarkan hal itu penulis mencoba membuat sistem informasi yang mudah digunakan dengan berbasis website dan database. Tujuan dari penelitian ini adalah merancang sistem informasi perpustakaan dan menerapkan klasifikasi Naive Bayes untuk membantu proses pencarian buku. Perancangan sebuah sistem informasi merupakan hal terbaik yang dapat digunakan untuk memecahkansebuah permasalahan yang ada. Sistem informasi berbasis website dapat digunakan, mulai dari pencatatan buku, anggota dan petugas perpustakaan, penyimpanan data-data yang berhubungan dengan proses peminjaman, sehingga saat proses pengembalian buku berlangsung tidak terjadi kesalahan. Dengan menggunakan metode Naïve Bayes Classifier yang merupakan pengklasifikasi probabilitas sederhana berdasarkan pada teorema Bayes. Keuntungan Naïve Bayes Classifier adalah hanya membutuhkan sejumlah kecil data pelatihan untuk memperkirakan parameter dalam proses klasifikasi. Hasil dari penelitian ini berupa aplikasi sistem informasi berbasis web yang berguna untuk mempermudah petugas dalam mengolah data buku serta mendapatkan pencarian yang lebih akurat.
Efektifitas Arang Tempurung Kelapa dalam Menurunkan Kadar Logam Perak dan Kromium pada Limbah Laboratorium
Authors: Darma Putra Deni
Published: April 2023

Laboratorium waste is one of the causes that can contaminate the environment. Heavy metal that can contaminate the environment such as silver metal (Ag) and Cromium metal should be removed.The purposefor this research is for remove silver metal (Ag) and Crom metal from the laboratorium waste.Method thatuse in this reasearch is completely randomized factorial.The result of this analysis is show that charcoalcoconut shell is very effective to reduce silver metal (Ag) 85,49 %; 89,27 %; 93,01 %; 96;71 % and Crommetal (Cr) 13,81 %; 24,73 %; 31,92 %; 38,60 % at the addition of Charcoal coconut shell 0,5 g;1,5 g; 2,5g; 3,5 g in laboratorium waste.Result of varian analysis show thatconfidence level F count > F table atthe 95 % and 99 % , it means that addition of charcoal coconut shell give the significant result for removalof silver metal and Crom meta
The impact of a decentralised orthopaedic service on tertiary referrals in Cape Town, South Africa
Authors: MacQuene T , Du Toit J , Hugo D , Alexander M , Ramasar S , Letswalo M , Swanepoel M , Brown C , Chu K
Published: April 2023

Background. In South Africa (SA), district hospitals (DHs) have limited capacity to manage the high burden of traumatic injuries. Scaling up decentralised orthopaedic care could strengthen trauma systems and improve timely access to essential and emergency surgical care (EESC). Khayelitsha township in Cape Town, SA, has the highest trauma burden in the Cape Metro East health district.Objectives. The primary objective of this study was to describe the impact of Khayelitsha District Hospital (KDH) on acute orthopaedic services in the health district, with a focus on the volume and type of orthopaedic services provided without tertiary referral.

Methods. This retrospective analysis described acute orthopaedic cases from Khayelitsha and their management between 1 January 2018 and 31 December 2019. Orthopaedic resources and the proportion of cases referred to the tertiary hospital by all DHs in the Cape Metro East health district are described.Results. In 2018 - 2019, KDH performed 2 040 orthopaedic operations, of which 91.3% were urgent or emergencies. KDH had the most orthopaedic resources and the lowest referral ratio (0.18) compared with other DHs (0.92 - 1.35). In Khayelitsha, 2 402 acute orthopaedic cases presented to community health clinics. Trauma (86.1%) was the most common mechanism of injury for acute orthopaedic referrals. Of clinic cases, 2 229 (92.8%) were referred to KDH and 173 (7.2%) directly to the tertiary hospital. The most common reason for direct tertiary referral was condition related (n=157; 90.8%).

Conclusion. This study outlines a successful example of a decentralised orthopaedic surgical service that increased EESC accessibility and alleviated the high burden of tertiary referrals compared with other DHs with fewer resources. Further research on the barriers to scaling up orthopaedic DH capacity in SA is needed to improve equitable access to surgical care.
Characteristics of Neuropathic, Ischaemic and Neuroischaemic Diabetic Foot Ulcers- A Prospective Cohort Study
Authors: Singh Chabungbam Gyan , Sil Abhik , Sanyal Debopam , Mandal Arup
Published: April 2023

Introduction: Diabetic Foot Ulcers (DFU) can be divided into neuropathic, ischaemic and neuroischaemic types. Since the pathophysiology is different, it is important to ascertain the outcome data on the three subgroups of DFU. Aim: To compare and assess the differences in the characteristics and healing process of the three types (Neuropathic, Ischaemic, and Neuroischaemic) of DFU. Materials and Methods: A prospective cohort study was conducted from April 2019 to July 2021 in the Department of Surgery, Regional Institute of Medical Sciences (RIMS) Hospital, Imphal, Manipur, India. Age, gender, duration of diabetes mellitus, smoking, hypertension, glycosylated haemoglobin, aetiology of DFU, osteomyelitis, gangrene, estimated Glomerular Filtration Rate (eGFR), and presence of multiple ulcer were recorded. Healing time and outcome (healed, non healed and amputation) of ulcer were the dependent variable. Data collected were analysed using SPSS-version-21. Fisher’s-exact test was used for proportions. Analysis of the time needed for healing was performed using the Kaplan-Meier method. A p-value of <0.05 was taken as significant. Results: A total of 42 patients were recruited for the study and 29 (69%) were males. Patients in neuropathic, ischaemic and neuroischaemic DFUs were 18,14 and 10, respectively. Hypertension (100%) and smoking history (100%) were present in the ischaemic group. Maximum healing (88.9%) was seen in patient with neuropathic ulcers and maximum non healing (28.6%) and amputation (21.4%) occurred in ischaemic group. Mean (SD) heal time in days were 165.5 (4.62), 141.1 (9.17) and 86.4 (8.02) for ischaemic, neuroischaemic and neuropathic respectively (p<0.001). The average time in which 50% of patients (median) had healed wounds was 75, 136, and 171 days for neuropathic, ischaemic, and neuroischaemic ulcers, respectively. Conclusion: Neuropathic DFU has better healing than the other DFUs. Ischaemic DFU have maximum non heal ulcers and amputation.
Assimilation of Macronutrients by Maize as Influenced from Humic Substance Enriched with Micronutrients
Authors: Sagar R. , Kadalli G. G.
Published: April 2023

The aim of the current investigation was to determine if maize had the ability to assimilate macronutrients under the effect of humic substance that was enriched with micronutrients. A field experiment was conducted with 10 treatments replicated thrice using RCBD this in the College of Agriculture's V C Farm in Mandya, Karnataka, India during Kharif 2017. The findings showed that the treatment getting RDF + FYM @ 10 t ha-1 together with Enriched HS @ 5 L ha-1 30 DAS had substantially greater macronutrient content and absorption in grains and stover than the treatment receiving RDF + FYM @ 10 t ha-1 along with Enriched HS @ 2.5 L ha-1 30 DAS. Whereas lower macronutrients content was recorded for the treatment with RDF alone. Among different treatments, T10 treatment (T2 + Enriched HS @ 5 L ha-1 30 DAS) recorded significantly higher total uptake of N, P, K, Ca, Mg and S (225.30, 58.44, 91.03, 96.04, 60.86 and 59.47 kg ha-1, respectively). Whereas lower N, P, K, Ca, Mg and S uptake (141.90, 26.94, 40.28, 46.24, 22.37 and 22.27 kg ha-1, respectively) were recorded for the treatment with RDF alone (T1).
Comprehensive profiling of pathogenic germline large genomic rearrangements in a pan‐cancer analysis
Authors: Sun Zhe , Bai Chujie , Su Miaoyi , Tang Haimeng , Wu Xiaoying , Wang Yue , Bao Hua , Liu Xunbiao , Wu Xue , Shao Yang , Xu Bei
Published: April 2023

The presence of large genomic rearrangements (LGRs) has been heavily investigated in breast and ovarian cancer. However, correlations between LGRs and cancer types beyond these two have not been extensively profiled, likely due to the highly inefficient methods of detecting these types of alterations. This study utilized next‐generation sequencing (NGS) to analyze and classify the germline LGR profile in 17 025 cancer patients across 22 cancer types. We characterized newly identified LGRs based on predicted pathogenicity and took a closer look at genes that acquire both germline and somatic mutations within our samples. The detection method for LGRs was validated using droplet digital polymerase chain reaction (ddPCR) assay of commonly investigated LGR genes. In total, 15 659 samples from across 22 cancer types were retained for analysis after filtering. We observed that, in our cohort, the cancer types with the highest proportion of germline LGRs were ovarian cancer (4.7%), renal cell carcinoma (2.5%), breast cancer (2%), glioma (1.8%) and thyroid carcinoma (1.8%). Annotation of detected germline variants revealed several genes—MSH2, FANCA and PMS2—that contain novel LGRs. We observed co‐occurrences between germline LGRs in MSH2 and somatic single nucleotide variants/insertion and deletions (SNVs/InDels) in BRCA2, KTM2B, KDM5A, CHD8, and HNF1A. Furthermore, our analysis showed that samples with pathogenic and likely pathogenic germline LGRs tended to also have higher mutational burden, chromosomal instability, and microsatellite instability ratio compared to samples with pathogenic germline SNVs/InDels. In this study, we demonstrated the prevalence of pathogenic germline LGRs beyond breast and ovarian cancer. The profiles of these pathogenic or likely pathogenic alterations will fuel further investigations and highlight new understanding of LGRs across multiple cancer types.
Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation
Authors: Leszczynska Katarzyna B. , Dzwigonska Monika , Estephan Hala , Moehlenbrink Jutta , Bowler Elizabeth , Giaccia Amato J. , Mieczkowski Jakub , Kaminska Bozena , Hammond Ester M.
Published: April 2023

Local hypoxia occurs in most solid tumors and is associated with aggressive disease and therapy resistance. Widespread changes in gene expression play a critical role in the biological response to hypoxia. However, most research has focused on hypoxia‐inducible genes as opposed to those that are decreased in hypoxia. We demonstrate that chromatin accessibility is decreased in hypoxia, predominantly at gene promoters and specific pathways are impacted including DNA repair, splicing, and the R‐loop interactome. One of the genes with decreased chromatin accessibility in hypoxia was DDX5, encoding the RNA helicase, DDX5, which showed reduced expression in various cancer cell lines in hypoxic conditions, tumor xenografts, and in patient samples with hypoxic tumors. Most interestingly, we found that when DDX5 is rescued in hypoxia, replication stress and R‐loop levels accumulate further, demonstrating that hypoxia‐mediated repression of DDX5 restricts R‐loop accumulation. Together these data support the hypothesis that a critical part of the biological response to hypoxia is the repression of multiple R‐loop processing factors; however, as shown for DDX5, their role is specific and distinct.
Neuropathic Pain Associated With First Metatarsophalangeal Joint Osteoarthritis: Frequency and Associated Factors
Authors: Menz Hylton B. , Allan Jamie J. , Buldt Andrew K. , Landorf Karl B. , Cicuttini Flavia M. , Roddy Edward , Munteanu Shannon E.
Published: April 2023

Objective

To determine whether neuropathic pain is a feature of first metatarsophalangeal (MTP) joint osteoarthritis (OA).

Methods

A total of 98 participants (mean ± SD age 57.4 ± 10.3 years) with symptomatic radiographic first MTP joint OA completed the PainDETECT questionnaire (PD‐Q), which has 9 questions regarding the intensity and quality of pain. The likelihood of neuropathic pain was determined using established PD‐Q cutoff points. Participants with unlikely neuropathic pain were then compared to those with possible/likely neuropathic pain in relation to age, sex, general health (Short Form 12 [SF‐12] health survey), psychological well‐being (Depression, Anxiety and Stress Scale), pain characteristics (self‐efficacy, duration, and severity), foot health (Foot Health Status Questionnaire [FHSQ]), first MTP dorsiflexion range of motion, and radiographic severity. Effect sizes (Cohen's d coefficient) were also calculated.

Results

A total of 30 (31%) participants had possible/likely neuropathic pain (19 possible [19.4%], 11 likely [11.2%]). The most common neuropathic symptoms were sensitivity to pressure (56%), sudden pain attacks/electric shocks (36%) and burning (24%). Compared to those with unlikely neuropathic pain, those with possible/likely neuropathic pain were significantly older (d = 0.59, P = 0.010), had worse SF‐12 physical scores (d = 1.10, P < 0.001), pain self‐efficacy scores (d = 0.98, P < 0.001), FHSQ pain scores (d = 0.98, P < 0.001), and FHSQ function scores (d = 0.82, P < 0.001), and had higher pain severity at rest (d = 1.01, P < 0.001).

Conclusion

A significant proportion of individuals with first MTP joint OA report symptoms suggestive of neuropathic pain, which may partly explain the suboptimal responses to commonly used treatments for this condition. Screening for neuropathic pain may be useful in the selection of targeted interventions and may improve clinical outcomes.

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Precise Measurement of Grasping Force for Noncollaborative Infants
Authors: Jeong Wooseong , Yoo Seungsun , Lee Seonmin , Choi Hyeokjoo , Ma Yoohan , Lee Seonhak , Lee Dongju , Kim Mijin , Bae Hyunjin , Han Soyoung , Chang Jongwon , Kim CheolGi , Hyun Dong Choon , Ko Young Hwii , Lee Heejin , Kim Saeyoon , Lee Sungwon
Published: April 2023

Among the medical parameters used for infants, the grasping force is particularly important because it indicates their musculoskeletal and neurological development. Although several grasping force measuring devices have been developed for infants, their accuracy and reliability are limited owing to their direction‐dependent sensing mechanisms. It is challenging to calculate the direction and area of the ambiguous forces applied by infants, and pediatricians cannot control the grasping method used by them. In this study, a direction‐independent grasping force measuring device is proposed that features a high resolution (0.1 kPa), cyclic stability (20 000 cycles), and linear sensitivity (21.73 µV kPa−1), and high accuracy and reliability. The grasping forces (average, minimum, and maximum) of the left (normal state) and right (injection needle inserted: uncomfortable state) hands of a 1‐day old infant can be successfully analyzed using the proposed device. It can be used to obtain the standard grasping force data of infants, which can contribute toward understanding the correlation between the grasping force and neurological diseases. The proposed device can be used to quantitatively measure the grasping force of not only infants but also the elderly; therefore, additional studies may report that the grasping force can be a discriminable parameter for identifying neurological diseases.
Tailoring Group Delay Dispersion of Spatial Phaser using Anisotropic Metasurface and Polarized Incident Waves
Authors: Jiang Xiaonan , Liu Baiyang , Xu Wentao , Rashid Amir Khurrum , Shao Liyang , Yu Ming , Wang Hong , Cheng Qiang , Cui Tie Jun , Zhang Qingfeng
Published: April 2023

Metasurface‐based spatial phaser, exhibiting dispersive group delay responses, is able to perform real‐time analogue signal processing on the temporal spectrum of spatial electromagnetic waves, e.g., Fourier transformation, pulse chirping, pulse spread, and compression. The functionality of a spatial phaser is closely related to its group delay dispersion slope. For instance, for an up‐chirped incident pulse, the positive‐slope‐dispersion phaser spreads the pulse whereas the negative‐slope‐dispersion one compresses the pulse. Most reported spatial phasers exhibit fixed dispersion slopes and hence perform single functionality only, which cannot meet the demand of multifunctional systems in communication and sensing applications. In this paper, a new way is proposed to control and tune the dispersion slope of spatial phasers using polarization of incident waves, which is simpler and more efficient than conventional approaches based on tunable circuits. To verify the proposed method, a first‐order spatial phaser is designed and experimentally demonstrated within 9.4–10.6 GHz. It is able to generate negative‐slope, positive‐slope, and zero‐slope group delay dispersions, in case of x‐, y‐, and ±45°‐polarized waves. Such a reconfigurable phaser may find wide applications in integrated communication and sensing.
Evaluating parent‐implemented behavioral skills training for teaching firearm safety skills
Authors: Novotny Marissa A. , Miltenberger Raymond G. , Baruni Rasha R. , Maxfield Trevor C. , Larson Vanessa , Yampolskaya Svetlana
Published: April 2023

Research shows that behavioral skills training (BST) and in situ training (IST) are effective interventions for teaching safety skills to children. In addition, the efficiency of these interventions can be increased when parents, teachers, or peers are taught to implement them. The purpose of this study was to replicate Novotny et al. (2020) and evaluate a web‐based program for teaching parents to conduct BST to teach safety skills to prevent gunplay. We randomly assigned 18 children to the parent‐conducted BST group or a control group and evaluated the intervention in a posttest only control group design. Children in the control group or treatment group who did not score a three in the in situ assessment (do not touch, get away, and tell an adult) received IST from their parents and were assessed again. Results showed that safety skill scores were statistically significantly higher in the treatment group than in the control group. Furthermore, there was a statistically significant increase in safety skills scores following IST for children who received it.
Liver injury indicators and subsequent cancer development among non‐fatty liver population
Authors: Ito Hiroshi , Kimura Takeshi , Takuro Shimbo , Higashitani Michiaki , Yamamoto Kazuki , Kobayashi Daiki
Published: April 2023

Background

Little is known about the association between liver indicators (The FIB‐4 index, nonalcoholic fatty liver disease fibrosis score (NFS), and fatty liver index (FLI)) and cancer development in patients without preexisting liver disease.

Methods

We conducted a retrospective cohort study with participants who underwent voluntary health checkups and without fatty liver between 2005 and 2018. Our primary outcome was the development of any type of cancer, and its association with each liver indicator was evaluated.

Results

A total of 69,592 participants (mean age: 43.9 years, 29,984 (43.1%) were men) were included. During a median follow‐up of 5.1 years, 3779 (5.4%) patients developed cancer. Compared to participants with a low NFS, those with a medium NFS had a higher risk of developing any type of cancer (adjusted hazard ratio [HR]: 1.18, 95% confidence interval [CI]: 1.07–1.31), whereas those with a medium FIB‐4 index had a decreased risk of developing any type of cancer compared to those with a low FIB‐4 index (adjusted HR: 0.91, 95% CI: 0.83–0.99). Patients with higher scores tended to have a higher risk of digestive organ cancer, regardless of the indicator. A high FLI was also associated with an increased risk of breast cancer (adjusted HR: 2.42, 95% CI: 1.24–4.71); however, those with a medium FIB‐4 index (adjusted HR: 0.65, 95% CI: 0.52–0.81) and NFS (adjusted HR: 0.50, 95% CI: 0.35–0.72) had decreased risks of developing breast cancer compared to those with a high FIB‐4 index and NFS, respectively.

Conclusion

Among patients without fatty liver, a higher liver indicator score was associated with an increased risk of cancer in the digestive organs, regardless of the indicator. Notably, those with a medium FIB‐4 index or NFS had a lower risk of developing breast cancer, whereas those with a medium FLI had an increased risk.