bluuebunny/crossref_metadata_2025 huggingface dataset:
Vitamin D deficiency in a Portuguese epilepsy cohort: who is at risk and how to treat*
Authors: Cunha Inês Antunes , Saraiva Ana MR. , Lopes Pedro , Jesus‐Ribeiro Joana , Duarte Cátia , Leitão Fátima , Sales Francisco , Santana Isabel , Bento Conceição
Published: May 2021

Objective. The epilepsy‐related risk factors for vitamin D deficiency, particularly the use of enzyme‐inducing antiepileptic drugs (EIAEDs), and how to treat vitamin D deficiency in patients with epilepsy remain unclear. Our aims were to explore risk factors and the influence of EAIEDs in vitamin D status and to determine the efficacy of a daily dose of oral cholecalciferol (vitamin D3) in epileptic patients with vitamin D deficiency.

Methods. Clinical data were collected and 25‐hydroxyvitamin D (25(OH)D) serum levels were measured. All patients with vitamin D deficiency (25(OH)D .20 ng/mL) or insufficiency (25(OH)D from 21‐29 ng/mL) were treated with 6,670 IU/day cholecalciferol for eight weeks and 25(OH)D was then remeasured. Descriptive and inferential statistics were employed.

Results. A total of 92 patients (44.6% males), with mean age of 41.0±14.8 years, were included. Measurements of 25(OH)D revealed that 79.3% patients had abnormal levels: 56.5% were vitamin D deficient and 22.8% were vitamin D insufficient. The statistically significant risk factors for vitamin D deficiency identified were: number of AEDs, treatment with EIAEDs, low sun exposure, high body mass index (BMI) and a high frequency of epileptic seizures. After treatment, 25(OH)D mean level increased by 98.99% (regardless of EIAED use or being overweight).

Significance. In our sample, more than half of the adults with epilepsy showed 25(OH) D deficiency. Patients on EIAEDs had lower 25(OH)D levels. A daily dose of 6,670 IU cholecalciferol successfully led to the correction of 25(OH)D levels. A higher dose in obese patients or in patients taking EIAEDs may not be warranted and this should be considered in future guidelines for routine vitamin D deficiency treatment.
Chapeau de gendarme in a toddler points to focal epilepsy originating from the subcentral gyrus
Authors: Rüsch Christina T. , Bölsterli Bigna K. , Carosio Carlotta , Ramantani Georgia
Published: May 2021

The chapeau de gendarme sign or ictal pouting has been associated with focal epilepsy of frontal origin. The identification and characterization of this semiologic feature derive mainly from adult epilepsy surgery series, whereas paediatric cases have rarely been reported. Here, we present a 14‐month‐old girl with a chapeau de gendarme sign with eyes closed as the sole initial manifestation of left frontal lobe epilepsy. Brain MRI revealed an area suspicious for focal cortical dysplasia in the anterior aspect of the left subcentral gyrus, and ictal scalp EEG supported a seizure onset correlating with the lesion. This is the youngest reported patient with a chapeau de gendarme sign and the first to be associated with a lesion in the subcentral gyrus. Our observation extends the age range of patients presenting with this intriguing semiology and the range of localizations where it may originate. We propose considering the chapeau de gendarme sign as a hallmark of focal epilepsy in all age groups, including early life, and that presurgical evaluation should be timely initiated in patients with refractory seizures. [Published with video sequence].
Application of Routine Analysis Procedures to a Direct Mass Spectrometry Technique: Selected Ion Flow Tube Mass Spectrometry (SIFT-MS)
Authors: Perkins Mark , Langford Vaughan
Published: May 2021

In recent years the environmental and human health impacts of volatile organic compounds (VOCs) have become more apparent, resulting in increased analysis demand. The gold-standard chromatographic techniques continue to be employed for most laboratory analyses. However, they have made only modest gains in productivity over the years, and these gains are primarily due to automated sample preparation and injection. Alternatively, significant productivity gains for VOC analysis through faster sample analysis and reduced instrument maintenance could be achieved by adopting direct mass spectrometry techniques such as selected ion flow tube mass spectrometry (SIFT-MS). This article demonstrates that routine analysis techniques such as quality control checks, method validation, the method of standard additions, and internal standards are readily applied to SIFT-MS, simplifying adoption of the technique. In addition, workflows for analysis of chromatographically challenging species are simplified by using SIFT-MS. Sample throughputs are increased two- to 25-fold depending on the analytical procedure.
Вклад курения в смертность в России в 2019 году
Authors: Халтурина Дарья Андреевна , Замятнина Елена Сергеевна , Зубкова Татьяна Сергеевна
Published: May 2021

Потребление табака является фактором риска преждевременной смертности. В данной работе представлены расчеты вклада курения в смертность в России в 2019 г. по 27 причинам смерти для курильщиков и бывших курильщиков по полу и 5-летним возрастным группам.

Был произведен расчет доли курящих россиян по полу и возрасту, а также доли бывших курильщиков, бросивших курить 10 и менее лет назад, по данным РМЭЗ НИУ ВШЭ. Причины смерти, связанные с курением в настоящем и в прошлом, а также значения относительных рисков для ассоциированных с курением причин смерти, использованные для расчетов, были выбраны на основе систематических обзоров и когортных исследований. Расчет вклада курения в настоящем и прошлом (для бросивших курить 10 и менее лет назад) для каждой причины смерти по полу и 5-летним возрастным группам был произведен по формуле популяционной атрибутивной фракции (ПАФ) в многоуровневой форме. Данные Росстата по числу смертей, ассоциированных с курением в России, по причинам смерти, полу и 5-летним возрастным группам на 2019 г. были взяты из базы данных ФГБУ «ЦНИИОИЗ» Минздрава России.

По нашим расчетам смертность, ассоциированная с курением, в России в 2019 г. составила более 266 тыс. смертей, в том числе 226 тыс. среди мужчин и 40 тыс. среди женщин. На долю смертей от сердечно-сосудистых заболеваний пришлось 58%.

Эти расчеты позволяют оценить структуру смертности, ассоциированной с курением, по причинам смерти, полу и возрасту в современной России, задать ориентир для формирования политики в сфере борьбы против табака.
Региональные аспекты динамики использования русского языка населением Белоруссии в 2009–2019 годах
Authors: Соколов Александр Сергеевич
Published: May 2021

В статье рассматривается распространение и использование русского языка городским и сельским населением Белоруссии, региональные особенности языковой ситуации. Актуальность и новизна исследования связана с появлением данных переписи населения 2019 г., что требует их анализа, интерпретации, сравнения с данными предыдущих переписей и выявления современных тенденций динамики распространения языков. Рассматриваются территориальные различия доли городского и сельского населения Белоруссии, назвавшего русский язык родным и языком домашнего общения, в разрезе областей и районов, динамика этих показателей, выявление районов с максимальным и минимальным их значением и его изменением, показана разница между долей населения, назвавшего русской язык родным, и долей населения, назвавшего его языком домашнего общения, динамика и территориальные особенности этой разницы для городского и сельского населения. Установлены корреляционные связи между показателями распространения и динамики языковых показателей и рядом других характеристик районов. Исследование показало, что результаты переписи по показателю доли русского языка как родного для районов Брестской области в 2019 г. резко отличаются от других регионов по многим параметрам (среднее значение, стандартное отклонение, величина изменения, характер связи между долей населения, указавшим русский язык родным в 2009 г., и изменением этого показателя в 2009–2019 гг., разница между долей русского языка как родного и его долей как языка бытового общения и т. д.), выдвигаются предположения о причине этого явления. Раскрываются факторы, влияющие на искажение отражения реальной языковой ситуации данными переписи.
Artisanal Production of Prefusion-Stabilized SARS-CoV-2 Spikes v1
Authors: Rivest Jean-Francois , Goupil Claudia , Doyon Yannick
Published: May 2021

The two-part protocol presented here describes the establishment of a stable pool of 293-F cells expressing the HexaPro variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) spike (S) protein and its production and purification from the culture medium. CRISPR-Cas9-driven targeted integration of the expression cassette at the AAVS1 safe harborlocus streamlines cell line production. Engineered 293-F cells grown as suspension cultures in animal origin-free, chemically defined, protein-free medium allow purification to be performed directly from the culture medium with minimal cell processing steps. Yields of native and purified Spikes typically average 30-50 mg per liter of culture medium following tandem affinity purification using nickel-coupled and Strep-Tactin resins. Purified proteins bind recombinant ACE2 and mAb CR3022 in ELISA-based assays. Establishing an engineered cell line from cryopreserved 293-F cells takes approximately 4 weeks, and subsequent production and purification take between 9 and 14 days. As shown for the D614G mutation, this system can be readily adapted to study Spike variants.
Potency Test: Glucose Stimulated Insulin Release Assay v3
Authors: Islet Distribution Program Integrated
Published: May 2021

The goal of the Integrated Islet Distribution Program (IIDP) is to develop a uniform standardized shipping method among all the subcontracted IIDP centers that will result in minimal loss of quality or quantity of shipped islets (as compared to control islets remaining at the IIDP center). The objective of this Standard Operating Procedure (SOP) is to be a model for site-specific SOPs that define the method for quantitative determination of insulin released after glucose stimulation for proving the potency of the human islet preparation shipped by the IIDP. GSIR Overview: After overnight culture at 37°C (12 – 24 hrs), human islets are incubated with media containing a relatively low concentration of glucose (2.8 mM) and a sample of the supernatant is taken. Then the same islets are incubated with media containing a higher glucose concentration (28 mM) and a sample of the supernatant is taken. The amount of insulin present in both the supernatant samples is measured using a commercially available Human Insulin ELISA kit. The stimulation index is calculated by dividing insulin concentration of the supernatant from the 28 mM glucose incubation by the insulin concentration of the supernatant from the 2.8 mM glucose incubation. Reference: Purified Human Pancreatic Islets, Glucose Stimulated Insulin Release Determination by ELISA; DAIT, NIAID, NIH SOP Appendix, Document No. 3104, A03, Revision Number 03; Effective Date: 25 Oct 2010; Supersedes Date: 08 June 2010.
Poverty Suburbanization, Job Accessibility, and Employment Outcomes
Authors: Delmelle Elizabeth , Nilsson Isabelle , Adu Providence
Published: May 2021

The last decade of urbanization throughout many cities have seen a perceptible shift in the demand for centralized urban amenities while poverty has increasingly decentralized. Yet, the opportunity landscape of these shifting geographies of poverty and prosperity are not well understood. In this article, we examine how access to employment for low-income households has been impacted as a result of these changing geographies. Using a case study on the Charlotte metropolitan area we examine whether the suburbanization of poverty and reinvestment in the center city has reshaped the job opportunity landscape for low-wage residents. The objectives of this article are twofold. First, we calculate and map autobased accessibility from all neighborhoods in the Charlotte metropolitan area to job locations, differentiated by wage categories, in 2010 and 2017 to identify potential changes in the mismatch between low-income households and access to employment. We use a point-level employment dataset for these two years and calculate accessibility originating from census block groups. Second, we estimate the extent to which access to employment has affected employment rates and household incomes at the neighborhood level using a first-difference, spatial two-stage least squares model with instrumental variables. Our findings suggest that changes in accessibility had no significant effect on changes in neighborhood employment rates. However, we find evidence that increasing accessibility for lower-income households could have a positive effect on neighborhood median household incomes. Overall, the polycentric nature of Charlotte appears to have reduced the spatial mismatch between low-income workers and low-wage jobs.
‘Notorious Schools’ in ‘Notorious Places’? Exploring the Connectedness of Urban and Educational Segregation
Authors: Bernelius Venla , Huilla Heidi , Lobato Isabel Ramos
Published: May 2021

While the statistical link between residential and school segregation is well-demonstrated, in-depth knowledge of the processes or mediating mechanisms which affect the interconnectedness of the two phenomena is still limited. By focusing on well-functioning schools in disadvantaged neighbourhoods, our article seeks to scrutinise whether reputation can be one of the key mediators of the connection between residential and school segregation. Our study combines qualitative ethnographic interviews from four (pre-)primary schools with quantitative segregation measures in four urban neighbourhoods in the Finnish capital city of Helsinki to understand the connections between lived experiences and socio-spatial segregation. The results show that there appears to be a clear link between neighbourhood and school reputation, as schools in disadvantaged neighbourhoods are strongly viewed through the perceptions attached to the place. Despite the case schools’ excellent institutional quality and high overall performance in educational outcomes, there is a consistent pattern of the schools struggling with negative views about the neighbourhoods, which seep into the schools’ reputation. Since school reputation is one of the central drivers of school choices and is also linked to residential choices, the close connection between neighbourhood and school reputation may feed into vicious circles of segregation operating through schools. The results highlight the need for integrated urban policies that are sensitive to issues concerning school reputation and support the confidence and identity of pupils, reaching beyond simply ensuring the institutional quality of schools.
Family memories of Yuriy Vasylyovych Kozachenko
Authors: Kozachenko A. V.
Published: May 2021

The article is dedicated to the memoirs of the sister of the outstanding scientist, Doctor of Sciences in Physics and Mathematics, Professor Yuriy Kozachenko. It tells about the friendly and creative family of Kozachenkos, in which the future mathematician grew up. Some stories from the childhood of Yuriy Kozachenko are described with great warmth.
Investigation by X-ray photoelectron spectroscopy of the process of TiC synthesis during annealing of ТiН2/ТiО2/С in vacuum
Authors: Kryshchuk T. V. , Korduban O. M. , Ogenko V. M. , Medvedskij M. M.
Published: May 2021

Small dimensional transition metal carbides (MXenes) are promising materials for the development of photocatalysts and are highly efficient cocatalysts for industrial TiO_2 (P25). Thus, in the Ti_3C_2@TiО_2 nanocomposite obtained by layering Ti_3C_2 nanoplates, the ability to separate charge carriers increases due to the high electrical conductivity of TiC_{1-х}. The task of forming the TiC_{1-х}@TiО_{2-х} nanocomposite by direct synthesis with n-TiO_2 is promising, which allows to increase the quality of contact between the shell and the nanocomposite core and to reduce the number of intermediate stages of synthesis. In addition, highly dispersed TiC has high values of hardness, melting point, modulus of elasticity and shear and has the prospect of use in materials science in plasma spraying coatings. In work ТіС was synthesized on the surface of TiO_2 - the shell of the modified micropowder TiH_2/TiO_2/С during reductive annealing in vacuum using TiH_2 as a source of atomic hydrogen. After a series of annealing at 535 ºС - 600 ºС, the Ti2p- C1s- and O1s- spectra of surface atoms were obtained. The main stages of TiC synthesis in the TiO_2/С conversion reaction were established by the XPS method. The use of TiH_2 as a source of atomic hydrogen in nanosystems of the «core/shell» type is proposed for local synthesis on the surface of nanoobjects in a vacuum or inert atmosphere.
ELECTRONIC COURT AS A LEGAL AND ADMINISTRATIVE CATEGORY
Authors: Obrusna Svitlana , Ivanova Iryna
Published: May 2021

The purpose of the article is to define the content and determine the essence of e-court as a legal and administrative category based on the analysis of the current domestic legislation, international normative legal acts and lawyers’ opinions. Methods. The validity of theoretical provisions and recommendations for further research, as well as the reliability of the results are ensured by the use of a set of philosophical, general and special research methods. The dialectical method of scientific cognition is used as the main general research method. Formal legal and systemic structural methods are applied for studying normative legal acts regulating e-court functioning. Logical semantic method is used when formulating definition constructions. Results. It is noted that for the successful implementation of Electronic court project it is important not only to adopt relevant regulations and organizational measures, but also to develop a scientific concept within the science of administrative law. The content of the category has not got a legal definition in domestic law yet, although it has been legally formalized. The authors express the opinion that domestic legislation requires the concept formulation and consolidation at the legislative level – within the Law of Ukraine on the Judiciary and the Status of Judges. The importance of developing and adopting a separate law on distance e-justice is emphasized. It is highlighted that further introduction of e-court in Ukraine involves systematic actions. They are technical and information support of courts; development of measures and systems to ensure information security; legal regulation of responsibility in case of violations; measures to prevent cybercrime; court staff trainings; educational campaign among population, monitoring of the system effectiveness and its constant modernization, etc. All the above allows considering e-court as an administrative and legal category. Conclusions. As a result of the analysis, the authors suggest forming the awareness that e-court, as a legal and administrative category, is a component of e-government, a relatively independent and unique form of judicial administration and legal process based on information technology that provides a full cycle of documentation flow and litigation in an electronic format and has genuinely legal nature.
Self-Regulation Strategy Inventory—Self-Report (SRSI-SR) evidencias de validez, confiabilidad y equidad en estudiantes universitarios de la ciudad de Piura, 2020
Authors: Moscol Seminario Jimena , Olivas-Ugarte Lincol Orlando
Published: May 2021

La presente investigación tuvo como objetivo general analizar las evidencias de validez, confiabilidad y equidad del Self-Regulation Strategy Inventory—Self- Report. Participaron 189 estudiantes universitarios entre los 18 y 42 años. Dentro de los resultados obtenidos se encontró que los ítems 4, 8 y 9 no presentaban índices adecuados de homogeneidad corregida ni de comunalidad. Se constató las evidencias de validez convergente en relación con el autoconcepto y la autoeficacia académica y validez discriminante en relación a la ansiedad ante exámenes. Además, el análisis factorial exploratorio reportó cuatro factores con una varianza explicada de 69.55%, mientras que el análisis confirmatorio final, demostró ajuste del modelo de cuatro factores correlacionados (X2= 93.654, df= 71, X2/df= 1.31, CFI= .974, TLI= .967, RMSEA= .071, SRMR= .044). Además, se determinó la fiabilidad a través del coeficiente Alfa Ordinal reportando un índice en sus dimensiones de .85 en OT, .79 en HIR, .86 en OE, .86 en BI, y la fiabilidad total de .96. Finalmente se encontró evidencias de equidad por sexo y edad, afirmando que la comparación de puntuación del este instrumento en base a estas variable, serán válidas y confiables en posteriores estudios.
Estrés e inteligencia emocional en personas adultas durante la pandemia de la COVID-19 en Tacna 2020
Authors: Torres Ramos Luisa Elizabeth , Mamani Vargas Romy Dennis
Published: May 2021

El estrés es una reacción normal en la conducta del ser humano, y la inteligencia emocional (IE) desempeña un papel fundamental para que éste tenga éxito, ambos son atribuibles a factores psicosociales, sin embargo, debido a la situación que actualmente vivimos en nuestra sociedad por la pandemia COVID-19, surge la necesidad de estudiar ambas variables, estrés e IE, siendo la relación entre ambas aun poco exploradas. El presente estudio tuvo como objetivo identificar la relación que existe entre el estrés y la inteligencia emocional en habitantes de la ciudad de Tacna, en una muestra de 154 participantes voluntarios de ambos sexos. El diseño del estudio es no experimental, de corte transversal y de tipo correlacional. Para medir la variable estrés se utilizó el instrumento DASS-21 de dos dimensiones (ansiedad y estrés) y para medir la variable inteligencia emocional se utilizó el instrumento escala TMMS el cual incluye tres dimensiones (percepción, comprensión y regulación).  Los resultados obtenidos indican que hay relación significativa entre las dos dimensiones de la variable estrés y las dimensiones percepción, comprensión y regulación de la variable IE.
Viaje de estudios, organizadores gráficos en el pensamiento crítico en estudiantes universitarios
Authors: Menacho Carhuamaca Jaime David , Cadenillas Albornoz Violeta
Published: May 2021

El presente estudio se realizó en perspectiva de un análisis científico de la incidencia de los viajes educativos y los organizadores gráficos en el pensamiento critico de los estudiantes de una Universidad Privada de Lima, 2020. Se desarrolló dentro del enfoque cuantitativo, basado en el diseño correlacional causal. La población censal incluyó a 85 estudiantes de pregrado. Los instrumentos utilizados como el cuestionario de viaje de estudios educativos, cuestionario de organizadores gráficos y el cuestionario denominado evaluó mi pensamiento crítico permitieron comprobar que existe relación entre las variables. En ese sentido, se concluyó que el viaje de estudios y los organizadores gráficos inciden en el pensamiento crítico de los estudiantes. Asimismo, se evidencia una incidencia significativa del viaje de estudios y los organizadores gráficos en analizar información, proponer alternativas de solución y argumentar posición. Por lo tanto, se dará paso a la medición de los puntos críticos que generan falencias en inferir implicancias y se actuará sobre ello.
Palabras clave: viaje de estudios, estrategias educativas, enseñanza, aprendizaje, pensamiento crítico
La resiliencia como herramienta de cambio para alcanzar la felicidad en adolescentes de Lima Norte
Authors: Angeles Donayre Mariuccia Maisy , Manrique Tapia César Raúl
Published: May 2021

RESUMEN

El objetivo del estudio fue describir los niveles de resiliencia en adolescentes según sexo y edad cronológica. El diseño fue no experimental, transversal; de tipo cuantitativo descriptivo. Participaron 515 adolescentes de 10 a 12 años de edad. El instrumento utilizado fue el Inventario de Factores Personales de Resiliencia de Salgado. Los resultados a nivel general y en cuanto a edad y sexo, el nivel predomínate fue el promedio, seguido del nivel alto. Esto implica que en los adolescentes evaluados la resiliencia está en plena formación, la cual sería una herramienta de cambio ante situaciones adversas futuras que ellos pudieran experimentar. Por tanto, se debe trabajar mucho más en estas edades para que esta capacidad pueda mejorar en lo cognitivo y en lo emocional y así llegar a mejorar otros aspectos de su vida, incluida la felicidad.
Inteligencia emocional y clima laboral en un colegio de Morales 2021
Authors: Alamo Dávila Carlos Fernando , Carnero Tapullima Marina , Saavedra Meléndez Janina
Published: May 2021

La investigación pretendió conocer si la inteligencia emocional se relaciona con el clima laboral en los docentes de un colegio de Morales en el periodo 2020, fue un estudio de tipo básica y de diseño no experimental, de corte transversal y enfoque correlacional, participaron 60 docentes de ambos sexos como población y como muestra 40 docentes, que respondieron dos cuestionarios: el Inventario Emocional de BarOn para medir la inteligencia emocional y la Escala de CL-SPC de Sonia Palma para medir el clima laboral. Los resultados nos mostraron que existe correlación positiva baja con un valor de Rho = 0,392 y una significancia de 0,012 facultando de esta manera aceptar la hipótesis planteada respecto a la existencia de una correlación entre las variables estudiadas.
Propiedades psicométricas de la escala de Inteligencia Emocional TMMS-24 en adultos de Lima Metropolitana, 2020
Authors: Pérez Zarate José Fernando , Tuesta Chamorro Yermin Yolanda , Quispe Plaza Jacqueline Iraida
Published: May 2021

El presente estudio tuvo como objetivo analizar las propiedades psicométricas de la escala de Inteligencia Emocional TMMS-24 en una población adulta de Lima Metropolitana 2020. La investigación fue de diseño instrumental. Se encuestaron 430 participantes, de los cuales se realizaron filtros, obteniendo 211 buenos datos. La prueba utilizada es la escala TMMS-24 de Mayer y Salovey (1995), adaptada al idioma español por Fernández-Berrocal, Extremera y Ramos (2004). La escala tiene 24 ítems donde el ítem 5 presenta un bajo índice de homogeneidad, comunalidad y discriminación. En el Análisis Factorial Confirmatorio se utilizaron indicadores para analizar el ajuste del modelo, CFI = .838, TLI = 846, RMSEA = .070 y SRMR = .085. Al analizar la relación con otras variables, se encontró una correlación positiva con el WHO-FIVE (> .30) y una correlación discriminante con el DASS-21 (<.20). Por otro lado, en el análisis de confiabilidad muestro una mayor similitud entre alfa (.87) y omega (.85) en la dimensión Regulación. Finalmente, en el análisis de equidad se evidenció que la escala es invariante (∆CFI <.01; ∆RMSEA <.01) entre hombres y mujeres.
Encadenamientos y emprendimientos en zonas mineras: Caso Buriticá
Authors: Aristizábal Hernández Gustavo , Puerta Catalina , Cárdenas Mauricio , Penagos Melissa , Sucre Carlos G.
Published: May 2021

Esta publicación es un análisis del Programa de Encadenamiento Productivo (PEP) de Buriticá, un proyecto de desarrollo socioeconómico de la zona de influencia del proyecto minero de Buriticá en el departamento de Antioquia en Colombia. En la primera sección se plantea un análisis conceptual del modelo PEP, partiendo de una discusión en torno a la minería y el desarrollo sostenible. La segunda sección describe el PEP, sus fases, componentes y metodología; iniciando con una revisión de su implementación en los municipios de la zona de influencia del proyecto minero y finalizando con una presentación de los resultados obtenidos a lo largo de su ejecución. La tercera sección propone las bases conceptuales de una eventual fase subsiguiente del PEP, por medio de acciones orientadas a fortalecer la perdurabilidad de sus resultados en el largo plazo, a partir de la apropiación social de las dinámicas empresariales y sectoriales promovidas por el programa.
Weed Detection in Images of Carrot Fields Based on Improved YOLO v4
Authors: Ying Boyu , Xu Yuancheng , Zhang Shuai , Shi Yinggang , Liu Li
Published: May 2021

The accurate weed detection is the premise for precision prevention and control of weeds in fields. Machine vision offers an effective means to detect weeds accurately. For precision detection of various weeds in carrot fields, this paper improves You Only Look Once v4 (YOLO v4) into a lightweight weed detection model called YOLO v4-weeds for the weeds among carrot seedlings. Specifically, the backbone network of the original YOLOv4 was replaced with MobileNetV3-Small. Combined with depth-wise separable convolution and inverted residual structure, a lightweight attention mechanism was introduced to reduce the memory required to process images, making the detection model more efficient. The research results provide a reference for the weed detection, robot weeding, and selective spraying.
Filter Bank Multi Carrier Signal System for Frequency Selective Channels
Authors: Patchala Sarala , Maruvada Sailaja
Published: May 2021

Filter Bank Multicarrier (FBMC) frameworks are a subclass of multicarrier (MC) frameworks. The essential guideline, separating spectrum into many thin sub channels, may not be new, MC frameworks have seen wide appropriation. These days, multicarrier regulation frameworks dependent on the discrete Fourier transforms are usually used to transmit over recurrence particular channels subject to forceful noise aggravations. In any case, these handsets experience the ill effects of poor sub channel spectral control, that is, the measure of inter channel impedance isn't unimportant. It very well may be indicated that the framework execution reduces when it is dependent upon an unsettling influence with a large portion of its energy focused on a narrow frequency band. This Paper aims that identify the Filter Bank Multi Carrier (FBMC) performance. The MIMO system combined with the FBMC then identifies the over Frequency Selective Channel (FSC). Here the analysis for FSC, Flat fading model FBMC and system with MMSE equalization. The Prototype filters are analyzing the system performance characteristics. The Power Spectral Density (PSD) of the MIMO FBMC system for the given spectrum. The proposed systems are best to compare all existing technique and we measure the spectral efficiency of the system.
Получение биологически растворимых пленок на основе полимерных нановолокон и гидроксиапатита кальция
Authors: Бакболат Б. , Даулбаев Ч. Б. , Мансуров З. А. , Султанов Ф. Р.
Published: May 2021

В работе проведены эксперименты по получению биологически растворимых пленок на основе наноразмерных полимерных волокон и гидроксиапатита кальция. В результате определены основные параметры процесса электроформирования наноразмерных волокон с ГАП. Предложенный способ допускает укладку строго направленных нановолокон из полимера с диаметром от 50 до 500 нм. Применение различных типов электродов позволяет варьировать размер нановолокон. Изучены такие характеристики как вязкость раствора, величина высоковольтного напряжения и подобранны оптимальные параметры, которые позволили получить пленки избиологически растворимых полимерных нановолокон и ГАП. Также проведены эксперименты по внедрению в структуру пленки лекарственных препаратов.
Получение металлокерамических СВС-композитов на основе механохимически обработанных систем
Authors: Мофа Н. Н. , Садыков Б. С. , Баккара А. Е. , Журанова Г. С. , Султанова З. Л. , Мансуров З. А.
Published: May 2021

Представлен обзор результатов проведенных исследований по предварительной механохимической обработке (МХО) порошков кварца, кальцита, волластонита и алюминия в центробежно-планетарной мельницес использованием различных модификаторов в качестве поверхностноактивных веществ для увеличения дисперсности и реакционной способности минералов и алюминия в СВС-процессах при получении металлокерамическихизделий. Модифицированные при МХО частицы представляют собой композиционные образования и содержат в поверхностном слое элементы модифицирующих добавок, которые обеспечивают им высокую активностьи являются дополнительным компонентом, принимающем активное участие в последующем процессе СВС. МХО порошков исходных реагентов в присутствии модификаторов приводит к уменьшению индукционногопериода зажигания системы, изменению термокинетических характеристик горения и повышению максимальной температуры горения. Для систем с механоактивированной смесью на основе алюминия наблюдается полнаяконверсия используемых реагентов и формирование различной по прочности структуры в зависимости от используемого модификатора. Изменение прочностных характеристик, синтезированных СВС-композитов от режимовМХО исходных компонентов шихты коррелирует с образованием в продуктах синтеза волластонита, анортита, геленита, нитрида алюминия и карбида кремния.
El cooperativismo de trabajo visto desde la perspectiva obrera: apuntes para una nueva ley de cooperativismo de trabajo asociado en Puerto Rico
Authors: Colón Morales Rubén
Published: May 2021

El presente artículo persigue identificar las deficiencias presentes en la legislación puertorriqueña sobre cooperativismo de trabajo, y proponer aquellos cambios necesarios para hacerla capaz de promover cabalmente el desarrollo de cooperativas de trabajo asociado (CTA) como una alternativa a los problemas que implica el ordenamiento económico capitalista prevaleciente para la persona obrera. Ello, a partir del análisis e identificación de aquellos elementos inherentes al sistema de trabajo capitalista que deben de ser superados como producto de cualquier legislación que verdaderamente se proponga fomentar la asociación libre y democrática de trabajadores en empresas productivas gestionadas por éstos, superando la condición de trabajadores asalariados.

Recibido: 07 noviembre 2020Aceptado: 06 abril 2021
An ounce of prevention is worth a pound of cure: considerations for pharmacists delivering the National Diabetes Prevention Program
Authors: Dixon Dave L. , Sisson Evan M. , Pamulapati Lauren G. , Spence Rowan , Salgado Teresa M.
Published: May 2021

Prediabetes is highly prevalent in the United States affecting over 88 million adults. In 2010, the Centers for Disease Control and Prevention (CDC) established the National Diabetes Prevention Program (NDPP), an intensive lifestyle program consisting of a 16-lesson curriculum focused on diet, exercise, and behavior modification, with the ultimate goal to reduce progression from prediabetes to diabetes. Despite tens of millions of adults potentially qualifying to participate in the program, the uptake of the NDPP has been exceedingly low. As a result, the CDC has focused its efforts on engaging with local health departments and community partners, including community pharmacies, across the United States to scale-up enrollment in the NDPP. In this commentary we discuss factors affecting implementation of the NDPP in community pharmacies and other settings where pharmacists practice, including training, space, personnel, recruitment and enrollment, retention, and sustainability.
Separate Regulations Regarding the Recovered Territories in the Law of People’s Poland
Authors: Eckhardt Piotr
Published: May 2021

The paper contains an analysis of those legal regulations of the People’s Poland which were specific to the Recovered Territories and an attempt to answer the question of why such regulations were created. The following sources of law are discussed: legal acts devoted entirely to the Recovered Territories; legal acts applied to the entire territory of Poland in which some provisions were devoted exclusively to regulating the situation in these areas; legal acts that formally applied to the entire territory of Poland, but in the Recovered Territories their regulations were of particular importance. The internal regulations of the Ministry of the Recovered Territories were also examined.
Intuicja w zarządzaniu – problematyka i kierunki badań
Authors: Kiełtyka Leszek , Jędrzejczyk Waldemar
Published: May 2021

In this chapter the author presents an issue concerning the usefulness of intuition in management. A review of the literature in order to show the current state of knowledge about the nature of intuition and its importance in the management processes has been made. Moreover the subject of research conducted by various research centers has been described synthetically. The research objectives of own research have been presented in it. On the basis of the analysis of the obtained results new questions have been generated, defining new directions of research in the field of intuition in management.
Treatment of meconium peritonitis in the antenatal and postnatal periods during pregnancy and after childbirth (a clinical case)
Authors: Ovsyannikov F. A. , Ryabokon' N. R. , Bairov V. G. , Suhotskaya A. A. , Zazerskaya I. E. , Korolev M. V.
Published: May 2021

Introduction. This article describes a clinical case of a pregnant woman with fetal meconium peritonitis and further observation and treatment of the child. Meconium peritonitis, being aseptic intrauterine peritonitis, is a serious disease that requires an integrated approach. Tactics of management the fetus, intrauterine risks and prognosis of survival in this pathology as well as choice of the technique for correcting meconium peritonitis and its complications during pregnancy and after childbirth are discussed.Material and methods. Prenatal ultrasound examination revealed in a male fetus signs of low intestinal obstruction, distortion of bowel loops, calcifications, ascites and polyhydramnios. This case shows that depending on the clinical course of peritonitis the timely performed diagnostics reduces risks of life-threatening complications.Results. Due to the newly developed ultrasound criteria which assess the pathology severity (meconium ascites, compression of the fetal chest cavity, edema and polyhydramnios), it became possible to predict the course of meconium peritonitis. Management of pregnancy, childbirth and neonatal period as well as therapeutic and surgical correction of this severe pathology with further early rehabilitation are described in details.Conclusion. Meconium peritonitis is a pathology in which a timely established prenatal diagnosis is extremely important because it significantly improves prognosis and allows to take adequate steps prenatally for stabilizing the condition of both a fetus and a pregnant woman.
Transoral technologies in treating congenital duodenal stenosis
Authors: Kozlov Yu. A. , Poloyan S. S. , Chubko D. M. , Smirnov A. A. , Mikhailov N. I. , Rasputin A. A. , Baradieva P. A. , Cheremnov V. S. , Ochirov Ch. B. , Koval'kov K. A. , Kapuller V. M.
Published: May 2021

Introduction. The transoral endoscopic surgery performed through the natural orifices of the human body can reduce the rate of complications associated with surgical procedures and general anesthesia.The aim of the present study was to reveal potentials in restoring the duodenal patency using NOTES technologies.Material and methods. The researchers assessed outcomes of surgical treatment of 4 patients with partial congenital duodenal obstruction who were operated on in two medical institutions of the Siberian Federal District: Ivano-Matreninsky Children’s Clinical Hospital in Irkutsk 2 patients and Maternity and Childhood Center in Krasnoyarsk 2 patients. The trial period lasted over the past 5 years, since January 2015. Two endoluminal techniques for restoring the duodenal patency were used balloon dilatation of stenosis and endoscopic membranotomy. In the final part of the study, demographic data, intraand postoperative parameters and treatment outcomes were analyzed.Results. All endoscopic procedures were successfully completed without conversion to laparotomy. In average, it took 25 minutes to restore the lumen of the duodenum (range 20-30 minutes). One patient showed moderate bleeding from the destroyed membrane after balloon dilatation which was stopped by electrocoagulation. Patients’ follow-up revealed that in one of them the disease returned one month later after the balloon dilatation. Repeated balloon dilation relieved the patient of the disease symptoms.Conclusion. Endoluminal techniques for treating congenital partial duodenal obstruction are feasible and can be successfully performed in most patients. Our experience has shown that this surgery can be done by both balloon dilatation and by endoscopic membranotomy.
Evidence-Based Nursing Management: Basing Organizational Practices on the Best Available Evidence
Authors: Haghgoshayie Elaheh , Hasanpoor Edris
Published: May 2021

Evidence-based nursing management, developed as a framework for improving the quality of decisions to provide the most effective health-care outcomes, is a synthesis of clinical expertise, research evidence, and patient values, to create effective patient care strategies. Effective use of evidence-based nursing management requires identifying the sources of evidence and assessing their utilization. This article suggests a model for evidence-based nursing management in nursing practice. The literature shows six sources utilized for nursing management decisions: scientific and research evidence, information from hospitals, political-social development plans, managers ‘professional expertise, ethical-moral evidence, and values and expectations of all stakeholders.
Transformational Executive Health-Care Leadership: What Makes a Good and Great Health-Care Leader?
Authors: Batheja Cyrus
Published: May 2021

Health-care leaders work at the highest levels of organizations and face unique challenges in today's health-care systems. This article reports the lived experiences of an executive nurse to better understand their leadership journey and leadership shadow, exploring their professional development of health-care leadership while navigating change and conflict by interpreting critical turning points in their career and triangulating data to identify and analyze central themes. Offering a real-world perspective, the article uses personal reflection aligned to professional inquiry, workplace observations, document reviews, and personal accounts to focus on executive nursing and the construction of a social movement from within a large managed care organization. The purpose of this evaluation is to create deeper understandings of ways in which to improve patient and provider experiences, reduce system waste, and improve population health. The theme of transformational leadership emerged, and new insights were created to inform future thinking.
Steroidal Glycosides from the Seeds of Hyoscyamus Niger L. and their Antifungal Activity
Authors: Lunga Irina , Chintea Pavel , Shvets Stepan , Favelb Anna , Pizza Cosimo
Published: May 2021

Phytochemical analysis of the seeds of Hyocyamus niger L. (Solonaceae) resulted in the isolation of six steroidal glycosides, two furostanol (1, 2) and four spirostanol saponins (3, 4, 5, 6), which were found in this plant for the first time. The structures of these compounds were determined by detailed analysis of their spectral data, including two-dimensional NMR spectroscopy and MS spectroscopy. The antifungal activity of a crude steroidal glycoside extract, fractions of spirostanoles and individual glicosides was investigated in vitro against a panel of human pathogenic fungi, yeasts as well as dermatophytes and filamentous species.
Application of NMR Technique in the Elucidation of Marine Natural Compounds
Authors: Ciavatta M. L.
Published: May 2021

The topic of the seminar held in the Institute of Chemistry, Academy of Sciences of Moldova on 30th September in the frame of the joint Moldo-Italian seminar “New frontiers in natural product chemistry”, concerned the use of NMR techniques in the elucidation of natural products. Step by step, two marine compounds (Fulvyne C and Tritoniopsin A) belonging to different chemical classes have been analyzed, by using suitable NMR experiments. This powerful technique allowed the elucidation of compounds as fulvynes, long chain polyacetylenes with the same functional groups but differently located in the chain, as well as tritoniopsins, cyclic diterpenes with a new skeleton, providing further information on their relative and absolute stereochemistry.
Study Concerning the Possibility of Gamma-Spectroscopy Method to Determine the Total Potassium in Soils
Authors: Leah Tamara , Lozovaia Zoia
Published: May 2021

It was proved the possibility of determination the total potassium in soils by gamma-spectroscopic method with subsequent calculation of total potassium content in according to value of 40K isotope (expressed in Becquerel, Bq), using the formula: К2О, % = С . А, where: C – conversion coefficient, A – activity of isotope 40K in soil, Bq/kg. Conversion coefficient for chernozems of Moldova – C=0,00337.
Increase of Crop Yields on Seed Treatment by Environmentally Safe Complexones in Solutions
Authors: Nikolskiy V.M. , Tolkacheva L.N. , Khalyapina Ya.M. , Smirnova T.I. , Yakovlev A.A.
Published: May 2021

In the laboratory and plot experiments the effect of ethylenediaminedisuccinic acid (EDDS) and iminodisuccinic acid (IDS) on chlorophyll content in wheat germ leaves and adult plants was investigated. It was estimated that both complexons increased chlorophyll content in leaves and crop yield.
Narrativas de estudantes de comunidades tradicionais no ensino superior
Authors: Pimentel Adriana Miranda , Moraes Paulo Alberto Sobral de
Published: May 2021

O artigo apresenta resultados de uma pesquisa que busca conhecer saberes e práticas de estudantes indígenas e quilombolas em uma universidade brasileira por meio da análise de narrativas na perspectiva fenomenológica-hermenêutica. Dois aspectos centrais foram identificados em seus relatos: diferenças entre modelos vivenciados na educação básica e no ensino superior; preconceitos sofridos por serem quilombolas ou indígenas. As histórias dos/as estudantes remetem a situações vividas individualmente durante o processo de formação e/ou a situações que dizem respeito a um grupo, uma etnia; revelam, ainda, que os contextos dos quais são oriundos/as têm sido alvo de descaso e desvalorização.
Education and the task of deconstructing the history of ontology
Authors: Silva Paulo Eduardo Lopes da
Published: May 2021

Throughout the history of Ontology, the comprehension of Being has often deviated from its original path and taken different directions. What are the consequences of this detour when it comes to the current conception about the phenomenon we call Education? From the Fundamental Ontology of Martin Heidegger until the considerations of other contemporary thinkers, this article proposes an involvement and commitment regarding the task of deconstructing the history of Ontology in order to enable an approach that unveils the most original essence of Education as παιδεία. This is the challenge that concerns all those who somehow confront the questions related to everydayness and the possibility of Dasein to find its truth even in face of the dictatorship of the ‘they’ (das Man). Therefore, the aim of these reflections is to offer a new and introductory perspective that can open a horizon of projects in which we become transparent to ourselves in our resoluteness (Entschlossenheit).
As implicações da reforma do novo ensino médio na prática e na formação docente em filosofia
Authors: Rodrigues Neuza Ferreira , Ferreira Sônia Maria Lira
Published: May 2021

Com a chegada do novo Ensino Médio, o ensino de filosofia mais uma vez sofre um golpe, voltando ao campo da instabilidade das políticas educacionais ao deixar de ser uma disciplina obrigatória. Compreender a aceitação e a recusa dos estudantes no que se refere ao estudo de filosofia nesse cenário é primordial para garantir a sobrevivência dessa disciplina no atual contexto educacional. Por isso, os professores de Filosofia são convocados a repensar o ensino de filosofia e a formação docente, abordando esse problema filosófico, na tentativa de superar a visão negativa da disciplina no Ensino Médio. A metodologia realizada na pesquisa foi a pesquisa-ação, seguindo o método fenomenológico.