bluuebunny/crossref_metadata_2025 huggingface dataset:
North Sumatran Malay Folktales: Its Structure, Social Function and Meaning
Authors:   Faculty of Cultural Sciences, Universitas Sumatera Utara, Indonesia, Zein T. Thyrhaya
Published: May 2021

This study is a descriptive-qualitative analysis that uses the techniques of observation, interviews and written documents. The Systemic Functional Linguistic (SFL) approach based on the principle of semiotics is used in this study. The data analysis consists of folktales found in North Sumatra, that is, “Batu Belah Batu Betangkup”, “Putri Kuau” and “Sri Putih Cermin”. By using the SFL approach this study describes the structure, social function, and meaning of North Sumatran Malay folktales. From the analysis it is found that the structure, function and meaning of all the three NSM folktales are similar. The material and verbal processes found in the texts of the folktales depict life in the palace and the everyday life of North Sumatran Malay society in the past as well as in the present. North Sumatran Malay texts are the representation of culture and meaning in which the value of of North Sumatran Malay society are inherent. Keywords: folklore, “Batu Belah Batu Betangkup”, “Putri Kuau”, “Sri Putih Cermin”, systemic functional linguistics, North Sumatran Malay values Abstrak Kajian ini merupakan penelitian deskriptif-kualitatif yang menggunakan teknik pengamatan, wawancara dan kepustakaan. Pendekatan Linguistik Sistemik Fungsional (LSF) yang berdasarkan prinsip semiotik digunakan dalam kajian ini. Data kajian terdiri daripada cerita rakyat yang terdapat di Sumatera Utara, iaitu “Batu Belah Batu Betangkup” , “Putri Kuau” dan “Sri Putih Cermin” . Dengan menggunakan LSF kajian akan mengungkapkan struktur, fungsi sosial, dan makna cerita rakyat Melayu Sumatera Utara (MSU). Daripada analisis didapati struktur, ketiga-tiga cerita rakyat MSU ini memiliki struktur, fungsi, dan makna yang mirip. Proses material dan verbalnya yang terdapat dalam teks cerita rakyat menunjukkan cerminan kehidupan istana dan sehari-hari masyarakat Melayu Sumatera Utara baik yang terjadi pada zaman dahulu maupun masa kini. Teks Melayu Sumatera Utara mewakili budaya dan makna sebagai nilai yang dijunjung dan dijiwai oleh masyarakatnya. Keywords: cerita rakyat, “Batu Belah Batu Betangkup” , “Putri Kuau” , “Sri Putih Cermin” , linguistik fungsional sistemik, nilai Melayu Sumatera Utara
Unsur Berahi dalam Pantun Kasih Sayang Melayu Brunei di Sabah
Authors:   Unit Penyelidikan Warisan Borneo, Universiti Malaysia Sabah, Low Kok On
Published: May 2021

Suku kaum Melayu Brunei telah menetap di sepanjang persisiran pantai barat Sabah sejak dari zaman awal Kesultanan Melayu Brunei lagi. Seperti suku kaum Melayu lain di Nusantara, berpantun ialah sebahagian daripada budaya mereka yang istimewa sejak dari dahulu hinggalah sekarang. Dalam kerja lapangan yang telah dijalankan di beberapa buah kampung Melayu Brunei di sekitar pantai barat Sabah, sejumlah pantun yang bertemakan cinta dan kasih sayang telah dirakamkan, ditranskripsi dan didokumentasi. Pantun kasih sayang yang terkumpul ini, antaranya menonjolkan unsur-unsur rasa rindu, jatuh hati, naik berahi dan hajat di hati untuk merisik dan meminang. Selain mendokumentasi sejumlah pantun yang bertemakan cinta dan kasih sayang, tumpuan kupasan dalam makalah ini adalah terhadap unsur “berahi” yang terbayang dalam pantun kasih sayang orang Melayu Brunei. Selain itu, perbandingan terhadap pantun cinta Melayu Brunei di Sabah dengan pantun cinta Melayu dan Tionghoa Peranakan terpilih juga akan dilakukan. Menerusi kupasan sedemikian, keistimewaan perasaan cinta dan berahi dalam budaya suku kaum Melayu Brunei di Sabah akan tertonjol kepada pembaca. Kata kunci: Melayu Brunei, pantun cinta, kasih sayang, unsur berahi. Abstract The Brunei Malay ethnic group settled all along the western shores of Sabah since the early part of the formation of the Brunei Malay Sultanate. As is the case with other Malay ethnic groups in Nusantara, reciting the pantun is part of their unique culture since the bygone days until the present time. In a field study conducted in several Malay Brunei kampongs along the western shores of Sabah, a number of pantuns with the themes of love and affection were recorded, transcribed and documented. These love pantuns that have been collected , among other things highlight the elements of yearning, falling in love, feeling amorous and wanting to seek a person’s hand in marriage. Apart from documenting some pantuns with the themes of love and affection, the focus of this article is on the element of lust which is reflected in these pantuns of love of the Brunei Malays. In addition, a comparison will be made between these love pantuns and selected Malay and Straits-born Chinese pantuns. By making this analysis, the uniqueness of the elements of lust and affection in Brunei Malay pantuns will be unravelled. Keywords: Brunei Malay, loved pantun, affection, elements of lust
The Image of the Europeans in Hikayat Mareskalek
Authors:   Faculty of Arts and Social Sciences, University of Brunei Darussalam, Taslim Noriah
Published: May 2021

This article discusses the Hikayat Mareskalek as a work of etiquette literature intended to instruct the Malay rulers through a European character. The 18th/19th centuries were a time that saw the emergence of not only new types of writing but also new genres modelled on those introduced by the Europeans; the date of production of this hikayat falls during this time. Under the influence and patronage of Europe, transitional works such as these display a pro-European tendency in terms of the narrative point of view and he orientation of thought. However, fascination with Europe was not in fact total. Hikayat Mareskalek (Maarschalk Willem Daendels), written by Abdullah al-Misri in Pontianak in 1815, is one of the works that does not display such a tendency. Although this hikayat mentions a European in its title, he is not the subject of the narrative; instead the writer cleverly exploits and manipulates his characteristics, attitudes and actions to act as a “mirror” reflection for the Malay rulers. Keywords: Hikayat Mareskalek , Maarschalk Willem Daendels, etiquette genre, Abdullah al-Misri, reflection of Malay rulers Abstrak Makalah ini membicarakan Hikayat Mareskalek sebagai sebuah genre adab yang mengajar raja-raja Melayu melalui watak dan perwatakan seorang pentadbir Eropah. Hikayat ini ditulis pada abad ke-18/19, iaitu abad yang menyaksikan kemunculan bukan sahaja bentuk kepengarangan jenis-jenis baharu tetapi juga pengenalan genre baharu yang bermodelkan bentuk penulisan yang diperkenalkan orang Eropah. Di bawah pengaruh dan naungan Eropah, karya transisi memperlihatkan kecenderungan untuk bersifat pro-Eropah dari sudut subjek penceritaan dan orientasi pemikiran. Namun, fenomena pesona Eropah ini sebenarnya tidak berlaku secara menyeluruh. Hikayat Mareskalek (Maarschalk Willem Daendals) yang ditulis oleh Abdullah al-Misri di Pontianak pada tahun 1815 ini merupakan antara karya yang tidak memperlihatkan kecenderungan sedemikian. Walaupun hikayat ini menggunakan orang Eropah sebagai judulnya, tetapi tidak menjadikannya subjek penceritaan, sebaliknya dengan bijak mengeksploitasi dan memanipulasi seluruh sifat, sikap dan tindak-tanduknya untuk tujuan menjadi “cermin” kepada raja-raja Melayu. Kata Kunci: Hikayat Mareskalek, Maarschalk Willem Daendals, genre adab, Abdullah al-Misri, cermin raja-raja Melayu
The Dialogues between Kresna and Arjuna Concerning the Swadarma of a Ksatriya in the Bhagavad Gita of the Ancient Javanese Bhisma Parwa
Authors:   Faculty of Arts, Udayana Universiti, Denpasar, Bali, Indonesia, Suastika I Made
Published: May 2021

The Bhagavad Gita is usually called the fifth veda ( pancama veda ), together with the four Sanskrit Vedas, namely the Rig Veda , Atharwa Veda , Sama Veda and Yajur Veda . The Balinese are familiar with the five vedas, and know the Bhagavad Gita as the sixth book of the ancient Javanese version of the Mahabharata epic. The Bhagavad Gita that features as a part of the ancient Javanese version of the Bhisma Parwa is ascribed to King Teguh Dharmawangsa Anantavikrama Uttunggadewa of the Kediri Kingdom in the 10th century CE. He is credited to have been responsible for ordering the translation of the Mahabharata (known in Bali as Asta Dasar Parwa —the 18 parwas). This translation effort from Sanskrit into the ancient Javanese language was dubbed mangjawaken Byasamata (translating into Javanese the works of the sage Byasa). The ancient Javanese version of the Bhagavad Gita contains the dialogues between Kresna and Arjuna about the swadarma (holy obligations and responsibilities) of a ksatriya (warrior) according to his wangsa (social class). A ksatriya was deemed responsible for defending his country, fighting against the enemy, as well as for upholding truth, satya wacana (truthfulness), lascarya (sincerity) and sradha bhakti (devotional service). Keywords: Bhagavad Gita, Asta Dasa Parwa , satya wacana , lascarya , bhakti Abstrak Bhagavad Gita sering disebut veda yang kelima (pancama veda) disamping empat veda yang ada, iaitu Rig Veda, Atharwa Veda, Sama Veda dan Yajur Veda berbahasa Sanskrit. Di Bali kelima-lima veda itu, termasuk Bhagavad Gita yang terdapat pada teks Bhisma Parwa, buku ke-6 daripada Mahabharata versi Jawa kuno. Empat veda dan Bhagavad Gita telah dibaca oleh masyarakat Bali dalam rangka mendapatkan ajaran tuhan untuk memperkuat nilai etika dan moral. Episod Bhagavad Gita berbahasa Jawa kuno terdapat dalam Bhisma Parwa digubah oleh Raja Teguh Darmawangsa Anantavikrama Uttunggadewa pada abad ke-10 Kerajaan Kediri. Raja Dharmawangsa Teguh menjadi manggala dalam penciptaan Mahabharata (di Bali disebut Asta Dasa Parwa atau 18 Parwa) memerintahkan rakawi untuk menyadurnya. Program alih bahasa yang disebut Mangjawaken Byasamata (mengalihbahasakan ajaran Begawan Byasa) yang sumbernya berbahasa Sanskrit kepada bahasa Jawa kuno. Bhagavad Gita Jawa kuno berisi dialog antara Krisna dan Arjuna tentang fungsi seorang kesateria dalam melaksanakan swadharma, iaitu tugas atau kewajiban suci seorang kesateria berdasarkan kelahirannya (wangsa). Tugas seorang kesateria adalah untuk membela negara dan mempertahankan negara, berperang melawan musuh, membela kebenaran, membela ucapan (satya wacana) dengan tulus ikhlas (lascarya) dan pengabdian (sradha bhakti). Kata kunci: Bhagavad Gita, Asta Dasa Parwa, satya wacana, lascarya, bhakti
The Expression of Emotion in Selected Modern Poems
Authors:   Jabatan Bahasa Melayu, Universiti Putra Malaysia, Mohd Salleh Nurul Afifah Adila , Abd. Rahim Normaliza
Published: May 2021

Emotions may be expressed in several ways, be these verbal or non-verbal. At first, emotional reaction can be illustrated through a person’s physical and cognitive development and is represented by the language in the linguistic form. This study focuses on the expression of emotion in selected modern poems. The objective of this research is to identify the types of emotions and explain the effects and influences of these emotions in modern poetry. This research was conducted employing a qualitative method to analyse the content of the text. Five modern poems from selected books were used as data. The theoretical framework of Mohd Azhar Abd Hamid (2004) which revolves around the expression of emotion was used as the basis for analysis and discussion in this study. The findings reveal that the five poems studied employ language that depicts both positive and negative emotions. This study is of great importance to writers and composers of poems, in order to ensure that what they wish to express is understood and appreciated by the listener or reader of the poems. Keywords: expression of emotion, modern poetry, feelings, language, meaning Abstrak Ekspresi emosi seseorang boleh digambarkan menerusi beberapa cara, iaitu melalui lisan dan bukan lisan. Pada peringkat awalnya, emosi dapat digambarkan melalui reaksi fizikal seseorang kemudian berlaku perkembangan kognitif dan dilambangkan melalui bentuk linguistik, iaitu bahasa. Kajian ini memberikan fokus terhadap ekspresi emosi dalam puisi moden terpilih. Objektif kajian adalah untuk mengenal pasti jenis emosi dan menghuraikan kesan emosi dan pengaruhnya dalam puisi moden. Penyelidikan ini menggunakan kaedah kualitatif, iaitu menganalisis kandungan teks. Lima teks puisi moden daripada buku yang terpilih dijadikan bahan untuk mendapatkan data. Kerangka pemikiran Mohd Azhar Abd Hamid (2004) yang berkisar tentang ekspresi emosi akan dijadikan prinsip dalam penganalisisan dan perbincangan kajian ini. Hasil kajian mendapati bahawa, lima puisi moden tersebut menggunakan bahasa yang menggambarkan emosi sama ada emosi negatif atau positif. Kajian ini memberikan kepentingan kepada penulis puisi dan pemuisi agar apa-apa yang disampaikan dapat difahami dan dihayati oleh pendengar atau pembaca puisi tersebut. Kata kunci: ekspresi emosi, puisi moden, perasaan, bahasa, maksud
Prinsip dan Konsep Teori Moral Alamiah dalam Novel Sa.b.a!
Authors:   Sekolah St. Andrew, Bandar Seri Begawan, Chong Ah Fok
Published: May 2021

Kajian dalam makalah ini menerapkan prinsip dan konsep teori moral alamiah pada struktur permukaan terhadap novel Sa.b.a! . Novel ini karya Haji Abdul Aziz Tuah, penerima SEA Write Award 2015 untuk negara Brunei Darussalam. Perbincangan dalam makalah ini mengungkapkan novel berdasarkan konsep dan prinsip teori moral alamiah. Novel ini didapati menepati keadaan, kejadian dan proses pembentukan alam ciptaan Tuhan. Kajian ini memperlihatkan bahawa novel hasil ciptaan pengarang itu berlaku dengan adanya restu Tuhan. Pengarang sama seperti unsur alam yang lain mampu membentuk sesuatu yang akhirnya menjadi sumber alam juga. Dalam hal ini karya sastera (novel) yang menggabungkan pengalaman dan ilmu pengetahuan menjadikan teks sebagai sumber alam ciptaan pengarang. Sementara itu naratif di dalamnya dapat disamakan dengan mimpi yang mengandungi peristiwa yang misteri bentuknya, namun ada pengalaman dan ilmu di dalamnya. Pembentukan teks novel ini seperti kejadian alam yang mempunyai kepelbagaian, keseimbangan dan keharmonian. Kewujudan atau penciptaannya tidak sia-sia tetapi mengandungi manfaat, sesuai dengan kejadiannya yang berfaedah dan indah sebagai iktibar kepada manusia. Kata kunci: alamiah, pencipta, mimpi, objek, naratif, permukaan Abstract This paper examines the principles and concepts of natural moral theory in the novel “Sa.b.a!”, the works of Haji Abdul Aziz Tuah who is the recipient of the 2015 SEA Write Award for Brunei Darussalam, on its surface structure. The discussion in this paper is to express this novel in conformity with the principles and concepts of nature moral theory, which is meet the situation, events and processes of nature the creation of God. This study shows that the novel of the author’s creation has occurred with God’s blessing. Author, like other nature elements are capable of forming something that eventually becomes a source of nature as well. In this case the literary work (novel) that combines experience and knowledge into text becomes the source of nature the author’s creation. Meanwhile narratives in novel can be likened as a dream that contains a mysterious event but there is experience and knowledge in it. The formation of this novel’s text is like natural occurrence of nature that has diversity, balance and harmony. Its existence or creation is not futile but it contains usefulness in accordance with nature occurrence, beneficial and beautiful, as a lesson to human beings. Keywords: nature, creator, dream, object, narrative, surface
Zosimos of Apollonia-Sozopolis
Authors: TALLOEN Peter , PRODANOVA Maya
Published: May 2021

Saint Zosimos of Apollonia-Sozopolis, a soldier who was reputedly martyred in the ancient region of Pisidia (SW Turkey) during the reign of the emperor Trajan (98-117 AD) after resigning from the Roman army to become a Christian, is a relatively unknown saint celebrated by the Greek Orthodox Church on the 19th of June. In modern scholarship, he is discussed as a soldier who originated from ancient Apollonia Pontica - Sozopolis in the Roman province of Thracia on the western Black Sea coast, and resigned from the Roman army in Pisidia, where he was martyred. This characterisation of Zosimos as a Thracian soldier is a case of mixed identities, or better, of mixed origins. It is the aim of this article to demonstrate that the Apollonia/Sozopolis referred to in the sources concerning the saint is not the Bulgarian city of Sozopol where the saint is still worshipped today but the homonymous city located in the northwestern part of ancient Pisidia in modern Turkey. A textual analysis of the Passio of Zosimos will offer several indications for this. The article also looks for the origins of the Passio of Zosimos: several elements mentioned in the text demonstrate that the account of the saint’s martyrdom was most probably a late antique construct, part of the abundance of hagiographical texts produced in late antiquity. It may have been composed to emphasize the position of Apollonia-Sozopolis as a major centre of early Christianity within the province of Pisidia during the 5th and early 6th centuries. There is subsequent evidence for the veneration of Zosimos at Gračanica in Kosovo and at Sozopol in Bulgaria, and the paper will try to establish why the cult of this Pisidian saint eventually came to be centred at Sozopol in Bulgaria, where he is still the object of veneration today.
Inschriften auf Stein-Sarkophagen von der Hisardere-Nekropole von Nikaia
Authors: MERİÇ Aygün Ekin , DREYER Boris
Published: May 2021

In dem Artikel werden neben einer Grabstele für ein christliches Grab zwei Sarkophage mit Inschriften untersucht, die in der Nekropole Hisardere in Iznik (Nicaea) gefunden und auf die römische Kaiserzeit datiert wurden. Der erste der Sarkophage gehört dem Antigonos, der im Alter von 45-50 Jahren starb. Antigonos wurde in ein dreischichtiges Wolltuch gewickelt und mit einer Glasflasche aus dem 3. Jahrhundert n. Chr. als Grabgeschenk begraben. Besonders das Leichentuch an Händen und Füßen ist intakt. Das Holzkissen unter dem Kopf und ein Teil des Holzbettes unter dem Körper blieben ebenfalls erhalten. Die Inschrift enthält eine Klage der Arete, die sich vielleicht mit dem Bildprogramm der Reliefs verbinden lässt. In dem zweiten Sarkophag liegen zwei weibliche Individuen, 30-45 Jahre alt und 25-30 Jahre alt, von denen aus der Inschrift hervorgeht, dass es Mutter und Tochter sind. Sie wurden fest in ein Leichentuch aus Leinen und lokaler Wolle und Seide gewickelt aufgefunden. Auf dem Sarkophag wurde ein Mosaik aus dem 4-5. Jahrhundert n. Chr. gefunden. Dieses Mosaik wurde entfernt, um das Grab zu öffnen. Beide Sarkophage haben den Zustand konserviert, in dem sie begraben wurden. Sie liefern so uns nützliche Informationen über die Bestattungstraditionen von Nikaia in der römischen Kaiserzeit und sind ein schönes Beispiel, wie die Zusammenarbeit der Disziplinen (Archäologie, Anthropologie, Epigraphik) fruchtbare neue Ergebnisse bieten können.
Church Building and Wine Making East of Ankara. Regional Aspects of Central Anatolia in the Early Byzantine Period
Authors: MİTCHELL Stephen , NIEWÖHNER Philipp , VARDAR Ali , VARDAR Levent Egemen
Published: May 2021

This paper reports early Byzantine carvings and inscriptions that were found in a survey of the eastern vicinity of Ankara/Ancyra in Galatia. Some fluted column capitals can be attributed to liturgical furnishings of early Christian churches. Some weights for wine presses are likewise decorated with Christian symbols and inscriptions. A cluster of finds from Kalecik/Malos echoes the fourth-century Life of St Theodotus of Ancyra. The symbol of a coiled snake refers to an ancient healing tradition that was originally associated with Asklepios, but appears to have continued in Christian times. Overall, the finds confirm the area’s ancient, and modern, reputation for wine making and show that healing cures were also provided. The formal repertoire and style of the carvings differ from other parts of the early Byzantine empire and lend additional distinction to central Anatolia as an early Christian Kunstlandschaft in its own right.
Neue Inschriften aus dem phrygischen Hochland
Authors: AKYÜREK ŞAHİN Nalan Eda , UZUNOĞLU Hüseyin
Published: May 2021

In this article, we present six inscriptions (one has already been published) discovered in the course of the on-going surveys in the Phrygian Highlands conducted by Rahşan Tamsü-Polat and Yusuf Polat from the archaeology department of Anadolu University (Eskişehir). Two of the inscriptions are ex-votos dedicated to Megistos Hosios, which are most likely to be associated with Hosios and Dikaios worshipped predominantly in Dorylaion and in its environs. In both of these dedications, the god appears as one deity and does not bear the name ‘Dikaios’, but has the epithet of Megistos, attested here for the first time. Two of the inscriptions are epi-grams. The first is an epigram comprising of one pentamer and 6 hexameters in verse. The in-scribed monument is erected by a certain Pasikrates who expresses his gratitude through this poem to his Lord Letoides (Leto’s son) i.e. to Apollon. In this epigram, Pasikrates list the names of his wife and many children along with their characteristics. The other poem is of the funerary epigram genre, belonging to a man called Karikos. According to the epigram, two lions were standing on the top of the funerary monument, apparently serving an apotropaic function. Even though these lions are missing today, the dowel holes visible on the monument were almost certainly employed to secure the recorded statues of two lions. In the epigram there is a sort of wordplay and the deceased seemingly performed something (i.e. θήρα = hunting) which bears the same name with these wild animals (θήρ), and this possibly indicates that Karikos was a hunter. The last two inscriptions (nos 5-6) are funerary inscriptions. The first is inscribed for Solon and Nana by their child Menodoros. The other is fragmentary. All of these inscriptions date from the Roman Imperial Period (2nd and 3rd century A.D.).
Formulation Development and Evaluation of Transfero-somes Nano Gel Loaded with Levocetirizine Transfero-somes
Authors: Bharath Mounika S , Rane Bhushan R , Jain Ashish S
Published: May 2021

A new drug delivery technology called transferosomes were came into existence which is an artificial vesicle designed to show the characteristics of a cell vesicle suitable for controlled and potentially directed drug delivery. Transferosome is a highly flexible and stress- responsive compound, complex compound and highly deformed vesicle with an aqueous core surrounded by the complex lipid bilayer thus enabling it to deliver both hydrophilic and hydrophobic drug. Urticaria is a general condition distinguished as brief erythematous and oedematous plaques or papules with defined erythematous borders and central clearing, identified as hives/wheals. Levocetirizine which is used for the treatment is a H1 anti histamine that is actively used in treatment of urticaria. The aim of the present research work was to investigate the potential of transferosome formulations for transdermal delivery of  levocetirizine. The transferosomes were formulated by lipid film hydration technique using Rotary vacuum Evaporator. In the present work levocetirizine vesicle was efficaciously formulated using an appropriate ratio of tween 80 and soya lecithin and was incorporated into gel since gel formulations are easy to administer and patient compliance. Levocetirizine transferosomes was evaluated for vesicle characteristicslike zeta potential, poly-dispersibility index, TEM, and stability study. Theaverage sizes of transferosome were found to be 566.6nm and poly dispersity index (PI) was found to be 0.532, zeta potential of the transferosome was found to be -2.3 mV which indicates that transferosome formulation is stable. Levocetirizine gel was prepared by using various concentrations of Carbopol 934 and is evaluated for their gel characteristics like pH, viscosity, Spreadability, extrudability, homogeneity, drug content, diffusion etc. Gel containing 2% Carbopol show best and promising results. Levocetirizine transferosomal gel were efficaciously formulated by utilizing levocetirizine transferosome which was prepared by thin film hydration method by using soya lecithin and tween 80 in the ratio 85:15. Other Oral formulation used in treatment for urticaria have disadvantage like poor bioavailability, 1st pass metabolism, patient non-compliance etc. Transferosome nano gel loaded with levocetirizine transferosome was found to be more effective than other oral formulations used in treatment for urticaria since transferosome are capable of passing through lipid layer and delivering drug into systemic circulation with maximum bioavailability.
Mechanism Underlying the Inhibitory Effect of Bio-synthesized Silver Nanoparticle on TNF-α induced NF- κB Nuclear Translocation in Prostate Cancer Cells
Authors: K Rajathi , K.B Leneeygreen , S Suja
Published: May 2021

Apoptosis, a physiological mechanism of highly orchestrated cell death, can be initiated by extracellular and intracellular mechanisms that trigger a complex machinery of proapoptotic proteases and mitochondrial changes, leading to the activation of specific endonucleases and DNA fragmentation. The present study was undertaken to elucidate a mechanism underlying the inhibitory effect of biosynthesised silver nanoparticle on TNF-α induced NF-κB nuclear translocation in prostate cancer PC- 3 cells. The  cell cycle analysis of Prostate cancer PC-3 cells was examined by flow cytometry by using annexin V-FITC/PI staining. Effect of silver nanoparticles in oxidative stress ROS, Effect of biosynthesized silver nanoparticle on apoptosis in human prostate cancer cell line and apoptotic induction of TNF-α and NF-κB expression was studied by Flow cytometry in Prostate cancer PC-3 cell line. From the results it was observed that biosynthesized silver nanoparticle inhibits the cellular growth of human prostate cancer PC-3 cells and induces apoptosis. The ROS levels generated in response to silver nanoparticles were significantly higher in treated PC-3 cells than the control. The result indicates that cell death is mediated by ROS production, which might alter the cellular redox status, and it is a potential reason for cell death. Apoptosis of the silver nanoparticle treated PC-3 cells was accompanied by a reduction in the percentage of cells in G0/G1 phase and an increase in the percentage of G2/M phase cells, indicating cell cycle arrest at G2/M phase, and transcription factor NF-κB plays an essential role in inflammation and cancer. The activation of NF-κB in response to inflammatory cytokine such as TNF-α promotes nuclear migration to enable DNA-binding activity and facilitate target genes expression.
Synthesis and Antimicrobial Screening of Some Novel 5-Substituted-1,10b-dihydroimidazole[1,2-c]quinazoline Derivatives
Authors: Rabari Haribhai , Vankar Hetal , Prajapati Beenkumar
Published: May 2021

The emergence of multidrug microbial resistance is the main challenges that the modern scientists have so far been facing in the recent era. In this respect, new series of drug classes having potential to give antimicrobial effect have been synthesized. A new series of 5- substituted-1,10 b-dihydroimidazole[1,2-c]quinazoline derivatives 8a-e have been synthesized and screened for antibacterial activity and antifungal activity. Synthesized derivatives were characterized by IR, MASS and 1H-NMR spectroscopy. Synthesized compounds show good activity, which was comparable to the standard drug and it can be useful for the further clinical study. Antibacterial activity was evaluated against four different pathogenic bacterial strains like Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Pseudo-monas aeruginosa. Among the screened compounds, 8e show good antibacterial activity against Staphylococcus aureus and Escherichia coli with MIC of 50 and 100 μg/ml respectively. Antifungal activity was evaluated  against two strains of fungi. Among the synthesized derivates, compound 8c was emerged out as the potent antifungal compound against Candida albicans and Aspergillus niger with MIC of 25 μg/ml and 75μg/ml respectively. Compound 8e also shows good antifungal activity with MIC of 50 μg/ml against both Candida albicans and Aspergillus niger. The overall results of this study indicated that  synthesized quinazoline derivatives had the potential to act as an antibacterial and antifungal agent, hence further investigation is warranted.
Chemometrics and Monte-Carlo Simulation Assisted RP-LC Method for Estimation of Cinacalcet Hydro- chloride in Pharmaceutical Products
Authors: Bera Ravi Kumar Venkata Varaha , Panda Sagar Suman
Published: May 2021

Cinacalcet hydrochloride (CNT) is a novel calcimimetic agent widely used in the treatment of hyperparathy- roidism. For the first time, the authors utilized the novel concept of analytical procedure development employing several unique scientific tools for quantification CNT from its pharmaceutical dosage form. The objective behind the present work was to establish a scientifically sound and systematic work frame that overcomes the drawbacks of the earlier reported method for estimating CNT level in samples and ensuring superior method performance throughout the analytical life-cycle. In this  process, at first, the risky method variables were earmarked and were subjected to a response surface methodology, followed by Monte-Carlo simulation (MCS) based robust- ness-cum-optimization studies. The inclusion of the MCS approach assessed the method performance with no additional laboratory experimentation  and  established the innovative hyphenation's aptness with chemometrics tools. The control strategies were established based on analytical design space and method performance evaluation results by a simulative approach. The study revealed that methanol %, flow rate, and pH are the three critical method variables influencing analytical attributes: retention time, the number of plates, and tailing. The analytical conditions include a C18 column (150mm × 4.6mm, 5μm) with an isocratic mobile phase (80:20, % v/v) of methanol and 0.01M KH2PO4 buffer (pH maintained at 3.5 using orthophosphoric acid) flowing at 1.1ml/min. Diode array detection was performed at 282 nm. Method validation was befitting to federal needs as linearity (0.5-160 μg/ml), accuracy (>99%), and precision below 1% of relative standard deviation are indicative of method suitability for the purpose. In a nutshell, the present method describes a typical analytical workflow with the significant advantage of  obtaining  more excellent scientific information with less systematized experimentation. It was found suitable for routine quality control of CNT in drug substance and drug product.
Kebangkitan Penggunaan Candi Di Banyuwangi
Authors: Poniman Poniman
Published: May 2021

The existence of Hindus in the archipelago was mostly centered on Java at first. This can be seen historical evidence in the form of a temple that is still remaining. However, actually the temple is a continuation of the sacred buildings in the previous civilization. There was a change in the treatment of the temple at that time because the worshipers had changed their understanding as a result of the new theological understanding he was introducing. Humans in carrying out religious traditions coupled with their level of intelligence, they will always reduce what exists and will create new civilizations to free them from the confinement of previous traditions. Likewise, the reappearance of the use of temples as part of Hindu religious life in Banyuwangi, which he had long abandoned as a means of rituals as a sign of revival. So it raises problems that need to be researched related to "What is the Basis for the Resurrection of the Use of Temples in Banyuwangi". The theory used in this research includes; Talcot Parsons' Structural Functional, Van Genneb's of Life Needs, Symbolic Interactionism, Theory of Religion. The methods used in qualitative research on the revival of the use of temples for the Hindi people in Banyuwangi include; In-depth Interviews, Participatory Observations, Documents, visual materials and data tracing published online.This study has the following results, including the basis for the revival of the use of temples: 1) There is a relationship between community systems, 2) the influence of reciprocal systems, 3) social integration, 4) social systems, 5) cultural revival, 6) agreement Together, 7) Historical Journeys.
Mitos Dan Religi Dalam ‘Geguritan I Dukuh Siladri’ Karya Sastra Kreatif Dan Dinamis
Authors: Sri Yudari A.A. Kade , Paramita I Gusti Agung , Ngurah I Gusti Ayu
Published: May 2021

This article is a small part of research report on the oral tradition of ‘Nyurud di Setra’ in the Klungkung-Bali Pakraman community Village Pemenang. One of the subsections reveals the relationship between myth and religion towards the traditional inherentance of Pura Dalem Suladri which is implicitly described in ‘geguritan I Dukuh Siladri’. With the qualitative  interpretative descriptive methods, it is understood that religion is one elements of universal culture which containts of beliefs and behavior related to supernatural power and powers. Meanwhile, myth is an important part of human life as a psychological necessity due to woory and fear of the wrath universe. In order for humans to avoid disaster, sacred and sacred stories are about objects that govern the universe are built, strengthened by sacred buildings and religious rituals. Thus, the‘geguritan I Dukuh Siladri’ appears to be a creative and dynamic literary work following the reality cummunity of social life according to the time.
Komunikasi Antarbudaya Dalam Interaksi Beragama Di Pura Bukit Karangasem
Authors: Pramesti Dasih I Gusti Ayu Ratna
Published: May 2021

The process of social interaction in the community is very close to communication and culture because of the harmonious reciprocal relationship. Culture and communication influence each other. Cultural differences will have the potential to cause uncertainty and anxiety disorders, so that the possibility of cultural shock occurs. The existence of a shift in the value of diversity, an important role of intercultural communication in bridging the obstacles to understanding society can be explained by intercultural interactions so as not to cause misunderstandings. This article analyzes the role of intercultural communication in religious interactions at Pura Bukit Kampung Anyar Karangasem using qualitative research methods. The results showed that: first, the historical background of the conquest of the Karangasem Kingdom over Lombok. Second, the process of adaptation and intercultural interaction carried out by Hindus and Sasak Bayan ethnic people creates religious social beliefs. Third, intercultural communication has implications for socio-religious interactions, such as: implications for religious values, implications for socializing activities, implications for the value of solidarity, and implications for the value of tolerance.
The Implementation Of Pitra Yadnya Ceremony In The Pandemic Covid-19 Time At The Hindu Community In Saksari Hamlet North Cakranegara Lombok
Authors: Patni R. Gusti Ayu Santi
Published: May 2021

This research aims to conduct a study regarding the implementation of the pitra yadnya ceremony during the Covid-19 pandemic in the Saksari hamlet, North Cakranegara subdistrict, Lombok. The background of this research is related to the habits of Hindus in this area to carry out the pitra yadnya ceremony by continuing the tradition of menyama braya, saling rojong, sidikara, and fraternal ties in creating harmony. The pitra yadnya tradition carried out by Hindus today is experiencing adjustments as a result of the spread of the Covid 19 pandemic, with social restrictions. In this regard, this research focuses on three formulations of problems, namely (1) how is the pitra yadnya ceremony; (2) what is the family strategy in implementing the pitra yadnya ceremony; and (3) what are the implications of the pitra yadnya Ceremony for community during the Covid-19 Pandemic in the Saksari hamlet, North Cakranegara subdistrict? This study was designed in a qualitative descriptive study to provide an overview of the implementation of the pitra yadnya ceremony at the research location. Based on the research results found three findings. First, the pitra yadnya ceremony procedures during the Covid-19 pandemic were carried out simply, without reducing the meaning of the ceremony, according to the concepts of iksa, sakti, desa, kala, patra, and tattwa. Second, the family strategy in carrying out the pitra yadnya ceremony during the Covid-19 pandemic is to continue to carry out the ceremony by following the advice and appeals of the Parisadha Hindu Dharma Indonesia (PHDI) or Hindu religious council and health protocols. Third, the implication of the pitra yadnya ceremony for the community during the Covid-19 pandemic is the change in the social order of the community, such as menyama braya, saling rojong, and sidikara, from an economic point of view, it was much more efficient than the situation before the Covid-19 pandemic.
QUALIDADE SANITÁRIA DE CENOURAS MINIMAMENTE PROCESSADAS E CENOURAS IN NATURA
Authors: Silva Kerly Francieli Belussi Francieli Belussi , Kozusny-Andreani Dora Inés , Andreani Junior Roberto
Published: May 2021

Objetivou-se nesta pesquisa avaliar a qualidade sanitária de cenouras minimamente processadas e cenouras comercializadas in natura. Nos procedimentos microbiológicos foram avaliados coliformes totais, coliformes termotolerantes e Escherichia coli, pesquisa para Salmonella spp., Foram isolados coliformes totais, coliformes fecais, Escherichia coli em 100% das amostras de cenouras in natura e em 20% das cenouras minimamente processadas. A concentração destes micro-organismos variou entre 103 e 109 UFC g-1. Salmonella spp foi isoladaem 93,3% das cenouras in natura. A elevada frequência de micro-organismos patogênicos, nas amostras de cenouras, evidenciou precariedade nas condições higiênico-sanitárias da cadeia de produção, as quais podem conduzir à contaminação e deterioração do alimento, comprometendo a qualidade do mesmo, bem como constituir-se em um risco a saúde pública.
GESTÃO DE EXPECTATIVAS NA AUDITORIA INTERNA: O CASO DE UMA INSTITUIÇÃO FEDERAL DE ENSINO
Authors: Praxedes Mariz Lawrence , Medeiros de Araújo Richard
Published: May 2021

O presente artigo tem como objetivo compreender como é realizada a gestão de expectativas na unidade de auditoria interna do Instituto Federal de Ciência e Tecnologia do Rio Grande do Norte - IFRN. A metodologia classifica-se quanto aos procedimentos, como descritiva e exploratória; quanto aos objetivos, estudo de caso e pesquisa documental; e quanto à abordagem, qualitativa. Para a coleta de dados, foram utilizados como instrumentos os registros e documentos institucionais, a entrevista individual com o Auditor-Chefe e o grupo focal com os auditores do IFRN. Os dados foram tratados por meio da análise de conteúdo e análise documental. Os resultados demonstraram que a fase de conhecimento (identificação e coleta das expectativas dos key stakeholders) possui uma rotina de procedimentos pré-definida, na qual o principal instrumento utilizado é o Levantamento de Informações. Quanto à fase de consideração das expectativas, verificou-se que a unidade não possui uma rotina de procedimentos para orientar os auditores nessa etapa, podendo provocar fragilidades ao trabalho da auditoria interna. Diante disso e considerando que a literatura aponta que o cenário atual evidencia o surgimento de novas expectativas e a ampliação destas em torno da auditoria interna, conclui-se que o momento da análise das expectativas das principais partes interessadas merece atenção, sendo relevante estabelecer procedimentos de orientação aos auditores, a fim de afastar ou mitigar as fragilidades detectadas.
PRODUTIVIDADE DO AMENDOIM EM FUNÇÃO DA APLICAÇÃO DE DOSES DE GESSO AGRÍCOLA NO INÍCIO DO FLORESCIMENTO
Authors: Fábio Leonardo Ângelo , Segato Silvelena Vanzolini
Published: May 2021

O cálcio é um nutriente pouco móvel na planta e que traz benefícios à cultura do amendoim. O gesso é uma fonte de cálcio e enxofre e pode ser usado em cobertura, no inicio do florescimento, visando promover aporte desse nutriente às plantas de amendoim, que o absorvem também pelas estruturas reprodutivas, notadamente o ginóforo. O presente trabalho teve como objetivo avaliar os componentes de produção e a produtividade do amendoim, em função da aplicação de diferentes doses de gesso agrícola, em área total, em cobertura, no início do florescimento. Foi utilizada a cultivar IAC-OL3, do grupo botânico Virgínia e os tratamentos constaram de quatro doses (0, 1000, 1500 e 2000 kg.ha-1) de gesso agrícola, no estádio fenológico R1. O experimento foi conduzido em Sertãozinho, SP e o delineamento experimental utilizado foi em blocos casualizados, com quatro tratamentos e cinco repetições. Cada parcela foi constituída por quatro linhas de 6m e espaçamento de 0,90m. Avaliaram-se componentes de produção e produtividade da cultura do amendoim. Conclui-se que a aplicação de 1000 kg.ha-1 de gesso agrícola, em cobertura, proporcionou um aumento de número de grãos por vagem, que refletiu em ganho significativo em produtividade.
AS INTERFACES DO PROCESSO DE CONSTRUÇÃO DE ESTRATÉGIAS IDENTITÁRIAS DE JOVENS EM CONTEXTO MIGRATÓRIO
Authors: Gracioli Maria Madalena
Published: May 2021

A inserção de jovens imigrantes na sociedade acolhedora perpassa diversos espaços de socialização: escolas, universidades, trabalho, espaços de cultura e lazer; são nesses ambientes que surgem oportunidades de convívio com jovens e com a cultura do país receptor. No entanto, nem sempre essa experiência se faz positiva; muitas vezes é permeada por estereótipos, preconceitos e discriminação, levando os jovens de forma consciente ou inconsciente, utilizar estratégias identitárias. Baseando-se nos estudos de Camilleri, Kastersztein e Taboada-Leonetti (2013) que discutem o conceito de estratégias identitárias, e, na investigação realizada a partir de um trabalho de campo elaborado por meio de entrevistas com jovens brasileiros com idade entre 16 e 24 anos, imigrantes em Portugal, identificamos e analisamos três tipos de estratégias identitárias utilizadas por esses jovens.
PERFIL, MOTIVAÇÃO E SATISFAÇÃO DO CONSUMIDOR VEGANO/VEGETARIANO NO MUNICÍPIO DE INDAIATUBA/SP
Authors: Carvalho Mota Isabel Carolina , Lopes Costa Barbara Regina , Araújo Richard Medeiros de
Published: May 2021

O objetivo deste estudo é analisar as variáveis que definem o perfil, motivação e satisfação do consumidor vegano referente a oferta de bares e restaurantes no município de Indaiatuba/SP. Este estudo aborda os principais conceitos sobre veganismo, segmentação de mercado e perfil do consumidor, assim como o breve resumo sobre o conceito e histórico do mercado vegano, o cenário atual brasileiro e o mercado vegano no município de Indaiatuba/SP. Metodologicamente foi um estudo com enfoque misto, sendo exploratória e descritiva, dada a contemporaneidade do tema e por expor características de determinada população. O questionário eletrônico continha 16 questões, a maioria de múltiplas escolhas, que geraram dados tratos por meio de estatística descritiva. Os resultados demonstram que, motivados pelos valores pessoais e a preocupação com o meio ambiente, os consumidores veganos estão insatisfeitos, sendo premente a necessidade de ampliar as opções existentes nos cardápios dos bares e restaurantes da cidade, bem como adaptações para atender o público vegano/vegetariano e entendimento sobre as limitações desses consumidores. Constatou-se também que ainda se trata de um perfil com características com baixa incidência ou um grupo social mais restrito, evidenciando um segmento com poucos adeptos (veganos) mas em expansão.
EFEITO DE FORMULAÇÃO DE FERTILIZANTE ORGANO-MINERAL LÍQUIDO NO CONTROLE DE NEMATOIDE DE GALHA EM BATATA
Authors: Rossi Carlos Eduardo , Oliveira Francisco Camargo de , Niro Brena Luiza Mateus , Santos Ana Caroline Candido dos , Paula Jaqueline Sales de
Published: May 2021

Os nematoides de galha são importantes pragas de solo para a cultura da batata, entre outras solanáceas, onde parasitam raízes e tubérculos causando prejuízos significativos para os produtores. O controle era feito exclusivamente com nematicidas, muitos dos quais foram banidos ou apresentam-se com uso muito restrito em razão de diferentes fatores ambientais e econômicos. O objetivo desse trabalho é testar um produto formulado a partir de fertilizante organomineral líquido contendo substâncias húmicas, nutrientes N, P, K (nitrogênio, fósforo e potássio), carboidratos, aminoácidos e extrato de nim (Azadirachta indica). O experimento foi conduzido em casa de vegetação com 8 tratamentos (diferentes combinações de aplicação no plantio e/ou na amontoa combinado ou não com abamectina) e 6 repetições. A parcela foi um vaso plástico com 21 L de substrato autoclavado e uma planta de batata ‘Ágata” inoculado artificialmente com Meloidogyne incognita. Os resultados demonstraram o controle exercido pelo formulado nas diferentes combinações de aplicação, à exceção do produto aplicado somente na amontoa. Entretanto, o controle do nematoide não repercutiu no desenvolvimento das plantas, onde não se verificaram diferenças estatísticas entre os tratamentos para todas as variáveis testadas.
Generación y segregación de residuos sólidos domiciliarios durante la cuarentena por Covid-19 en Panamá, estudio de caso
Authors: Requena Sánchez Norvin , Carbonel Ramos Dalia , Vallester Erick
Published: May 2021

La pandemia del Covid-19 ha provocado la declaratoria de cuarentenas en casi todos los países del mundo, en Panamá se mantuvo un confinamiento estricto entre los meses de marzo y setiembre. A pesar de la importancia de la gestión de los residuos sólidos en las ciudades la información sobre el impacto de la cuarentena en la generación y composición de residuos no ha sido lo suficientemente recopilada y difundida. En este estudio se presenta una metodología innovadora para recolectar información sobre los residuos domiciliarios sin salir de casa. Este trabajo muestra los resultados de una encuesta cerrada sobre hábitos de generación y segregación de residuos en seis provincias del país y los datos de caracterización y composición de los residuos sólidos domiciliarios en tres distritos de la provincia de Panamá. Los resultados de las encuestas evidencian las deficiencias del servicio de recolección de residuos en diferentes zonas del país. La generación per cápita domiciliaria de la provincia de Panamá es 0.409 kg/hab./día (27% de error y 0.23 de desviación estándar), este valor es menor a otros hallados previamente lo que podría deberse a una disminución en la capacidad de compra de las familias ocasionada por el desempleo a raíz de la cuarentena. En la composición de residuos la proporción de residuos orgánicos y peligrosos aumentó. Los residuos orgánicos pueden haber aumentado por una mayor frecuencia y cantidad de alimentos preparados en casa. El aumento de residuos peligrosos es un indicador importante para emitir recomendaciones que reduzcan el riesgo del personal de servicio de recolección de residuos