bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of open and laparoscopic outcomes of adult Type-I congenital choledochal cysts
Authors: Lu Hui , Hou Wailin
Published: September 2023

Objective: To compare open and laparoscopic outcomes of adult Type-I congenital choledochal cysts.

Methods: Clinical data of 78 adult patients with Type-I congenital choledochal cysts, who had undergone cyst resection and Roux-en-Y hepaticojejunostomy in Chenzhou First People’s Hospital from September 1, 2021 to August 31, 2022, were retrospectively analyzed. Patients who received open approach and Roux-en-Y hepaticojejunostomy constituted the open group (n=35,) and patients who received laparoscopic approach and Roux-en-Y hepaticojejunostomy were assigned into the laparoscopic group (n=43,). The intraoperative and postoperative conditions, relevant laboratory indicators, and the rate of complications were compared between the two groups.

Results: Intraoperative blood loss, postoperative time to first flatus, diet recovery time, time to drainage tube removal, and length of hospitalization of the laparoscopic group were lower in the laparoscopic group compared to the open group (P<0.05). One day after the operation, serum amylase (SAMY) levels in both groups were significantly lower, while the levels of total bilirubin(TBIL), alanine aminotransferase(ALT), and C-reactive protein(CRP) were higher than before the operation. Postoperative SAMY level in the laparoscopic group was significantly higher, while the postoperative TBIL and CRP levels were significantly lower than those in the open group (P<0.05). The incidence of postoperative complications in the laparoscopy group (4.65%) was significantly lower than the open group (20.00%) (P<0.05).

Conclusions: Laparoscopic cyst resection combined with Roux-en-Y hepaticojejunostomy is associated with lower extent of trauma, faster recovery, less inflammation, and fewer complications than open surgery in adult patients with Type-I congenital choledochal cysts.

doi: https://doi.org/10.12669/pjms.39.6.7829

How to cite this: Lu H, Hou W. Comparison of open and laparoscopic outcomes of adult Type-I congenital choledochal cysts. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7829

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Association between contrast-enhanced adenosine-stress perfusion cardiac magnetic resonance imaging and invasive coronary angiogram for the detection of coronary artery disease: A retrospective analysis
Authors: Khan Sher Bahadar , Ghaffar Rehmat , Muhammad Adil  , Jan Muneeb
Published: September 2023

Objective: The objective of this study was to determine the diagnostic value of stress perfusion CMR for the detection of coronary artery disease.

Methods: The was a retrospective cross sectional study in which 43 subjects were included from Cardiac MRI unit in the Hayatabad Medical Complex, Peshawar for study from 1st April 2020 to 30th November 2020. All the subjects who had been referred for stress perfusion CMR with suspected CAD were included in the study. Cardiac MRI both at rest and with adenosine stress perfusion was performed which was followed by invasive coronary angiography.

Result: A total of 43 patients were enrolled for the detection or exclusion CAD who underwent stress perfusion CMRI and invasive coronary artery angiography. The study revealed strong and statistically significant association between positive stress perfusion CMR and positive coronary angiogram vs negative stress perfusion CMR and negative coronary angiogram (p= value 0.0001).

Conclusions: Stress perfusion CMRI can be considered as a first line, relatively safe, noninvasive test with significant accuracy to diagnose coronary artery disease in patients with suspected CAD without subjecting these patients to invasive coronary angiogram

Abbreviations:CMR: Cardiac magnetic resonance imaging, CAD: Coronary artery disease, FFR: Free Fractional Reserve, MACE: Major Adverse Cardiovascular Events.

doi: https://doi.org/10.12669/pjms.39.6.8008

How to cite this: Khan SB, Ghaffar R, Adil M, Jan MU. Association between contrast-enhanced adenosine-stress perfusion cardiac magnetic resonance imaging and invasive coronary angiogram for the detection of coronary artery disease: A retrospective analysis. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.8008

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Application and impact assessment of an interactive journal club format among endocrinology fellows-in-training in a tertiary hospital academic center: a case study
Authors: Chiu Harold Henrison , Isip-Tan Iris Thiele
Published: September 2023

Background: The interactive journal club is designed to utilize a new approach in appraising research in order to maximize the benefits of the traditional journal club. In this new approach, the participants are actively involved in a structured process of critical data appraisal rather than just being passive listeners. In this case study, we applied the interactive journal club format and assessed its impact among our endocrinology fellows-in-training.

Methods: We conducted four interactive journal club sessions within a four-week span, one per each week via a virtual platform. The 12 participants were the same throughout all sessions. Each session was recorded following informed consent. At the end of all sessions, feedback was obtained, tabulated and compared.

Results: Sessions lasted from 59 to 83 minutes (mean, 67.75 minutes). Participants became more active and spontaneous as the sessions progressed. All participants found the format more fun and proactive. This approach allowed more critical thinking and processing of information. Salient features include increased self-esteem and confidence, additional learning from other participants, better retention of information, and utilization in future practice.

Conclusions: Traditional approaches are transformed from passive presentations of recent developments in medicine into an interactive discussion while allowing the retention of the spirit and essence of a traditional journal club, as well as exploring new and improved approaches in clinical training and education.
A study on biomedical researchers’ perspectives on public engagement in Southeast Asia
Authors: Tran Dong Thai Han , Van Thuy Qui Huong , Vu Duy Thanh , Fisher Jaom , Chambers Mary
Published: September 2023

Introduction: Public engagement is increasingly promoted in the scientific community. Although there are studies about researchers’ perspectives on public engagement, these are predominantly from Global North settings and there is little data from the context of Southeast Asia. The Oxford University Clinical Research Unit (OUCRU) is a clinical and public health research programme with sites in Vietnam, Nepal and Indonesia. There is a dedicated public engagement team, and it is recognised as an important part of the research process.  

Methods: Through this study we explored the views and needs of local researchers with regards to practicing public engagement. We obtained opinions of 70 researchers through an online survey with both open-ended and closed-ended questions.  

Results: Most researchers perceived public engagement as improving public science literacy, rather than supporting public participation in science and research. While the participants largely see public engagement as a necessary practice, they experienced four main barriers to taking part in public engagement: time, lack of capacity, lack of support and personal perceptions. Most participants indicated they had somewhat to low confidence to communicate about science to the public. Experience, skill and knowledge, and personal preference emerged as factors that influence their perceived confidence for science communication. In our analysis, experience appeared to be the main factor contributing to researchers' high confidence.  

Recommendations: We recommended to support researchers by not only providing them with training for skills and knowledge, but also with opportunities to conduct public engagement, and a range of methods to suit their personal styles of communicating. It is also evident that more support is needed to build an enabling institutional environment that gives researchers professional recognition for their engagement work. This study, while modest in its scope, has informed our approach to supporting researcher-led engagement, and may guide other institutes wishing to improve this.
The genome sequence of the Orange-tailed Mining Bee, Andrena haemorrhoa (Fabricius, 1781)
Authors: Crowley Liam M. ,   University of Oxford and Wytham Woods Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life programme,   Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: September 2023

We present a genome assembly from an individual female Andrena haemorrhoa (the Orange-tailed Mining Bee; Arthropoda; Insecta; Hymenoptera; Andrenidae). The genome sequence is 330.7 megabases in span. Most of the assembly is scaffolded into 7 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 16.46 kilobases in length. Gene annotation of this assembly on Ensembl identified 10,908 protein coding genes.
The genome sequence of the Six-striped Rustic, Xestia sexstrigata (Haworth, 1809)
Authors: Boyes Douglas , Mulley John F. ,   University of Oxford and Wytham Woods Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life programme,   Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: September 2023

We present a genome assembly from an individual female Xestia sexstrigata (the Six-striped Rustic; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome sequence is 638.3 megabases in span. Most of the assembly is scaffolded into 32 chromosomal pseudomolecules, including the W and Z sex chromosomes. The mitochondrial genome has also been assembled and is 15.36 kilobases in length. Gene annotation of this assembly on Ensembl identified 15,104 protein coding genes.
Administrative activity of internal affairs bodies
Authors: Zubach Anatoliy , Kostennikov Mihail , Kurakin Aleksey , Admiralova Irina , Vasilenko Gleb , Kalyuzhnyy Yuriy , Vahitov Amir , Veretenceva Irina , Kovrova Vera , Makareyko Nikolay , Polikarpova Ekaterina , Rukavishnikov Sergey , Sosnovskaya Yuliya , Alimova Elena , Epifanov Aleksandr
Published: September 2023

The textbook deals with administrative, legal and organizational issues related to the activities of internal affairs bodies. The general part of the textbook reveals the basic issues and features of the administrative activities of internal affairs bodies, its forms and methods, as well as highlights the intra-organizational administrative activities of services and divisions of internal affairs bodies and the status of management entities in the field of internal affairs at various levels. In a special part, the main directions of the activities of the internal affairs bodies for the protection of public order and ensuring public safety, as well as the administrative and procedural activities of the internal affairs bodies and the specifics of the activities of the internal affairs bodies in special conditions are considered.
Meets the requirements of the federal state educational standards of secondary vocational education of the latest generation.
For students (cadets) of secondary vocational education institutions (including educational institutions of the Ministry of Internal Affairs of Russia) studying in legal specialties, university students, postgraduates, teachers, as well as practitioners who improve their qualifications under additional professional education programs in the system of the Ministry of Internal Affairs of Russia.
Economics and Innovation Management
Authors: Kozlovskaya Era , Yakovleva Elena , Buchaev Yah'ya , Gadzhiev Magomedrasul
Published: September 2023

The textbook reveals the essence of innovation management in a complex of disciplines on the theory of situational and adaptive approach and practice of financial management and the essence of the problem
innovative development of the enterprise, the analysis of innovative activity of Russian enterprises is given. The theoretical aspects of innovation analysis are formed on the principles of systems theory, situational
innovation management and investment assessment methods, on the assessment of the economic efficiency of production. System analysis is presented as the basis of innovation process management.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For students of higher educational institutions studying in the field of training "Management" (profile "Innovative management"), under the master's program "Innovative Management" and in the scientific specialty 5.2.3 "Regional and sectoral economics".
Simulation modeling of sociotechnical systems: fundamentals of queuing theory
Authors: Pitelinskiy Kirill , Borodin Aleksandr
Published: September 2023

The textbook forms an idea of various principles and technologies of management of economic and technological systems and processes. A comparative analysis of the principles of construction and synergetic management of various organizational structures is given; the theoretical foundations of the theory of queuing and statistical methods used to build economic and mathematical models. The theoretical material is accompanied by the solution of examples and questions for self-examination. The practical application of algorithmic and software useful for the analysis of statistical characteristics of data arrays studied by means of simulation modeling is considered.
Meets the requirements of the federal state educational standards of higher education of the latest generation.
For students studying in the fields of "Economics" and "Management".
Labor law
Authors: Eremina Svetlana , Stepanova Elena , Akopov Dmitriy , Gubenko Marina , Kudryashova Svetlana , Suleymanova Galiya
Published: September 2023

The content of the textbook gives the necessary idea about the basic concepts, categories, institutions of the branch of law "Labor law". Taking into account the students' independent study of regulatory legal sources and special literature, the textbook is designed to promote the acquisition of professional knowledge on the regulation of relations included in the subject of this branch of Russian law. The training material is accompanied by control questions and tasks that will help to understand more deeply the key issues of labor law and learn how to apply its norms in practice.
Prepared on the basis of the Department of Civil Procedure and Labor Law of the Faculty of Law of the Southern Federal University (Rostov-on-Don).
Meets the requirements of the federal state educational standards of secondary vocational education of the latest generation.
For students of secondary vocational education institutions studying the course "Labor Law".
Cross-border transactions: development of tax administration tools
Authors: Advokatova Alena , Borisov Oleg , Goncharenko Lyubov' , Gurnak Aleksandr , Davlieva Sof'ya , Klochihin Georgiy , Knyazeva Anastasiya , Kolotovkin Igor' , Milogolov Nikolay , Polezharova Lyudmila , Tihonova Anna
Published: September 2023

The monograph, based on the study of the genesis and modern views, deepens the theoretical and methodological approaches known in science to models of taxation and tax administration of multinational companies and beneficiaries, as well as provisions on the place and importance of tax instruments in the development and implementation of socio-economic policy of the state. Proposals have been comprehensively developed to improve a number of mechanisms and tools for tax administration of cross-border transactions, fixed in the form of separate norms of tax legislation and forming a holistic concept for the development of tools for tax administration of cross-border transactions.
It is addressed to economists, lawyers, managers, managers and specialists of federal executive authorities of the economic block, as well as teachers, graduate students, undergraduates of economic and law universities and faculties, students of the advanced training system.
Logistics of new urban mobility: a value-oriented approach
Authors: Shul'zhenko Tat'yana , Zhuk Andrey , Ivanova Dar'ya
Published: September 2023

The monograph reveals the provisions of a value-oriented approach to the management of logistics systems of public urban passenger transport, relevant to the conditions of a client-centered economy and aimed at increasing the sustainability of the functioning of the passenger transport complex of the city in the context of the development of alternative forms of urban mobility. The ideological basis of the author's concept of a value—oriented approach is the understanding of the duality of the recipient of the services of the logistics system of urban public passenger transport - passengers and the city, which makes it possible to justify strategic decisions on the development of the logistics system of public urban passenger transport by balancing the parameters of service and passenger flows, achieved by meeting the needs of recipients while observing restrictions on their financing.
It is intended for researchers, representatives of executive bodies of state administration of the subjects of the Russian Federation and local self-government, providing the organization of transport services to the population in cities and urban agglomerations, designers of urban logistics systems, developers of transport and related services in urban mobility systems, as well as for teachers and university students. It can be useful for a wide range of people interested in the management of logistics systems, the development of urban public passenger transport, modern urbanism.
Personnel management in Russia: reboot. Book 11
Authors: Durakova Irina , Matasova Larisa , Mayer Ekaterina , Grigorov Ivan , Rahmanova Tat'yana , Mitrofanova Elena , Bagirova Anna , Razumova Tat'yana , Sapozhnikova Natal'ya , Dolzhenkova Yuliya , Grechko Tat'yana , Pugach Svetlana , Shatalova Nina , Mihaylov Fedor , Burak Irina , Saakyan Mariya , Mitina Natal'ya
Published: September 2023

The monograph contains the results of research concerning, firstly, new ideas about employees and about human resource management in the context of a reset of the labor market and sanctions restrictions. In the context of these directions, the competition factor is considered as an imperative to reset the supply and demand of labor, the specifics of the modern psyche and existential reality, the role of human capital in the sustainable development of the corporation. Secondly, the actual role of continuing education as a basis for the competitiveness of workers in a period of economic instability, its inclusive scenario and, as a consequence, knowledge, formed, including taking into account the policy of digitalization. Thirdly, issues of well—being, the content of which is a culture of caring and psychological safety of employees, including conditions of crisis economic development, an inclusive environment, family-friendly policy of the organization. Fourth, the problems of managing older workers in the concepts and practice of personnel management: professional success in aging societies, technology for achieving active longevity, training, productivity and remuneration. Fifth, resetting approaches to personnel management: the formation of an organization's culture in the context of the development of information and communication technologies, the development of a system of documentation support for personnel management in order to reduce personnel and legal risks.
For students, postgraduates and teachers of economic universities and faculties, as well as a wide range of readers interested in personnel management issues.
Health significance of body position during sleep - literature review
Authors: Sudelska Katarzyna , Sawińska Zuzanna , Tarsa Grzegorz , Kępka Przemysław , Łokczewska-Bojar Aleksandra , Kuziemkowska Daria , Kuźma Jan , Ben Rhaiem Rami , Skotalczyk Magdalena , Łącka-Majcher Anna
Published: September 2023

Introduction:
Sleep is a fundamental biological need of the body, crucial for maintaining health and body’s regeneration. The body position during sleep not only affects sleep quality and well-being but also influences various health aspects, such as obstructive sleep apnea, back pain or gastroesophageal reflux.
Aim of the study:
The aim of our study is to summarize the impact of body position during sleep on human health. We paid attention to the relationship between sleep position and aspects like: sleep quality, obstructive sleep apnea, back pain and gastroesophageal reflux.
State of knowledge:
The body position during sleep is crucial for maintaining mental and physical health. It affects sleep quality as well as health aspects such as: obstructive sleep apnea, back pain or gastroesophageal reflux disease. In the case of sleep quality, the most beneficial position is on the right side. The supine position is associated with worsened obstructive sleep apnea, while on the side - with reducing the frequency of symptoms. Neck pain is connected with an asymmetrical side and an upright  head position, while lower back pain is associated with a supine position. The described position that reduces the reflux of gastric contents into the esophagus, and thus reduces the symptoms of reflux disease, is on the left side and with an elevated head of the bed.
Summary:
Sleep position is significant for many aspects of human health. Besides affecting sleep quality and well-being, it also has an impact on conditions such as obstructive sleep apnea, back pain and gastroesophageal reflux.
The ‘inbetweeners’: living on a watch and wait approach for chronic lymphocytic leukaemia – a qualitative study
Authors: Dunnion Claire , Giltenane Martina , Dowling Maura
Published: September 2023

Background:

Chronic lymphocytic leukaemia (CLL) is an incurable disease; many people with the condition do not require active treatment and are monitored using a watch and wait approach.

Aim:

The aim of this study was to explore the experiences of people living with a diagnosis of CLL and on watch and wait.

Methods:

Using a descriptive qualitative approach, seven participants on the watch and wait approach were interviewed. Data analysis was guided by systematic text condensation.

Findings:

Participants reported anxiety, referring to ‘wait and worry’. Their information needs were not met, and they resorted to seeking information on possible future treatments themselves. They also experienced feeling like an imposter because they were not receiving active treatment like other patients with cancer.

Conclusions:

A greater understanding of how information provision affects levels of anxiety and worry among people living with CLL on watch and wait is needed. In addition, clinical nurse specialists could deliver education on the watch and wait approach, supplemented by video-based educational materials developed by the haematology team.
Facing up to new challenges
Authors: George Heather
Published: September 2023

In her series on the early steps of a newly qualified nurse, Heather George Critical Care Staff Nurse, Aberdeen Royal Infirmary ( heather.george2@nhs.scot ), describes working a shift in an unfamiliar setting
Challenges in prospective observational studies evaluating pressure ulcer costs: how to price the items correctly
Authors: Pokorná Andrea , Krupová Lenka , Benešová Klára , Mužík Jan , Jarkovský Jirí , Búrilová Petra , Dolanová Dana , Saibertová Simona , Klugar Miloslav , Krupa Miroslav
Published: September 2023

Objective:

Pressure ulcers (PUs) are a significant healthcare problem with a negative impact on patients' quality of life and incurring substantial healthcare expenses. Our study aimed to analyse the costs of treating PUs in hospitalised patients in the Czech Republic, in the context of current treatment procedures and price levels, and to pilot-test the detailed methodology developed.

Method:

A prospective, observational, non-interventional study was conducted at the Clinic of Anesthesiology, Resuscitation and Intensive Medicine, the Internal Medicine Department and the Surgical Department of the University Hospital Ostrava. The study included all hospitalised patients with a PU from March–May 2021. Data were collected using the hospital information system. A bottom-up, person-based approach to cost analysis was used, based on a comprehensive cost structure using accurate patient-specific consumption records.

Results:

The length of hospitalisations ranged from 1–31 (mean: 12.7) days. The average cost of PU treatment per hospitalisation was calculated at €1579. The average daily cost of PU treatment was €179, including antibiotic therapy (ATB) and €112 without ATB. Most of the costs were associated with ATB (38.6%) and caregivers' time (35.9%). Based on the results, a predictive model was developed to estimate the cost of treating a hospitalised patient with a PU, which could be used in future research to assess the costs of treating these patients.

Conclusion:

We have faced many challenges in the methodology of preparation of cost analysis (e.g., how to count amorphous topical agents and sprays, how to properly identify PUs, how to price the positioning aids and mattresses, and how to relate the ATB treatment to the PU). This analysis provides important input for developing a comprehensive and more accurate methodology for monitoring PU costs in hospitalised patients, applicable in clinical practice for inpatient healthcare providers.
Use of a dynamic tissue system and biological xenograft in complex traumatic wound closure
Authors: Collins Reagan A , Dang Michael , McReynolds Shirley , Puckett Yana , Ronaghan Catherine A
Published: September 2023

Objective:

Asymmetrical dimensions and nonlinear margins of a multilayered traumatic wound often preclude healing via primary intention. We present the case of an otherwise healthy 21-year-old male who sustained trauma following a boating accident.

Method:

The patient sustained three lacerations to the posterior thighs from the boat propeller. The most extensive wound measured 25×10×6cm of muscle extrusion with a divot fracture involving the posterior femur.

Results:

Primary closure and restoration of muscle biomechanics was achieved using a combination of a dynamic tissue system (DTS) and porcine urinary bladder matrix (PUBM) xenograft. After 24 days of treatment in hospital, the patient was discharged without the need for home health, outpatient wound care, or ongoing negative pressure wound therapy. The patient recovered full function of the legs and was cleared for participation in all activities.

Conclusion:

This complex traumatic boat propeller injury presented many challenges, including a transverse orientation on the extremity, degree of muscle injury/extrusion, and significant soft tissue loss. The combined application of a DTS with PUBM biological xenograft achieved a primary myocutaneous closure without the need for skin graft or flap reconstruction by plastic surgery.
Sclerotherapy and its complications: a literature review and a case report
Authors: Kravitz Steven , Kipp Jennifer , Gallagher Amanda
Published: September 2023

Hard-to-heal or recurrent leg ulcers can have multiple aetiologies. One of these is incompetent veins. The main focus of this article is to discuss the common treatment for venous leg ulcers with the use of sclerotherapy. This simple surgical procedure obliterates smaller veins and telangiectasia. Veins with larger diameters (varicosities) can be treated with ablation therapy. The intent of sclerosis or ablation therapy is to destroy the incompetent veins and allow the collateral circulation to improve venous return, decreasing venous hypertension, which then enhances skin closure, wound healing and the resolution of the ulcer.
Continuous renal replacement therapy with oXiris® in patients with hematologically malignant septic shock: A retrospective study
Authors: Wang Juan , Wei Shu-Run , Ding Tong , Zhang Li-Ping , Weng Zhi-Hua , Cheng Ming , Zhou Yang , Zhang Meng , Liu Fang-Jun , Yan Bei-Bei , Wang Dan-Feng , Sun Ming-Wen , Cheng Wei-Xin
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Comparing the efficacy of regen-cov, remdesivir, and favipiravir in reducing invasive mechanical ventilation need in hospitalized COVID-19 patients
Authors: Hegazy Sahar Kmal , Tharwat Samar , Hassan Ahmed Hosny
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Unveiling the hidden world of gut health: Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota
Authors: Zyoud Sa’ed H , Shakhshir Muna , Abushanab Amani S , Koni Amer , Shahwan Moyad , Jairoun Ammar Abdulrahman , Abu Taha Adham , Al-Jabi Samah W
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Efficacy of abatacept treatment in a patient with enteropathy carrying a variant of unsignificance in CTLA4 gene: A case report
Authors: Musabak Ugur , Erdoğan Tuba , Ceylaner Serdar , Özbek Emre , Suna Nuretdin , Özdemir Binnaz Handan
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Severe inflammatory disorder in trisomy 8 without myelodysplastic syndrome and response to methylprednisolone: A case report
Authors: Pan Fei-Yan , Fan Hao-Zhe , Zhuang Shun-Hong , Pan Li-Fei , Ye Xiang-Hong , Tong Hong-Jie
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Typical Zollinger-Ellison syndrome-atypical location of gastrinoma and absence of hypergastrinemia: A case report and review of literature
Authors: Zhang Jin-Ming , Zheng Chu-Wei , Li Xiao-Wen , Fang Zhi-Yun , Yu Mu-Xin , Shen Hai-Yan , Ji Xia
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Secondary pulmonary infection by Fusarium solani and Aspergillus niger during systemic steroid treatment for COVID-19: A case report
Authors: Usuda Daisuke , Kato Masashi , Sugawara Yuto , Shimizu Runa , Inami Tomotari , Tsuge Shiho , Sakurai Riki , Kawai Kenji , Matsubara Shun , Tanaka Risa , Suzuki Makoto , Shimozawa Shintaro , Hotchi Yuta , Osugi Ippei , Katou Risa , Ito Sakurako , Mishima Kentaro , Kondo Akihiko , Mizuno Keiko , Takami Hiroki , Komatsu Takayuki , Oba Jiro , Nomura Tomohisa , Sugita Manabu
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon diagnosed by molecular pathology: A case report and literature review
Authors: Jiang Meng , Yuan Xiao-Ping
Published: September 2023

Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and iftar (after dusk). However, diabetic patients may face difficulties when fasting, so it is important for medical staff to educate them on safe fasting practices. Prolonged strict fasting can increase the risk of hypoglycemia and diabetic ketoacidosis, but with proper knowledge, careful planning, and medication adjustment, diabetic Muslim patients can fast during Ramadan. For this review, a literature search was conducted using PubMed and Google Scholar until May 2023. Articles other than the English language were excluded. Current strategies for managing blood sugar levels during Ramadan include a combination of patient education on nutrition, regular monitoring of blood glucose, medications, and insulin therapy. Insulin therapy can be continued during fasting if properly titrated to the patients’ needs, and finger prick blood sugar levels should be assessed regularly. If certain symptoms such as hypoglycemia, hyperglycemia, dehydration, or acute illness occur, or blood glucose levels become too high (> 300 mg/dL) or too low (> 70 mg/dL), the fast should be broken. New insulin formulations such as pegylated insulin and medications like tirzepatide, a dual agonist of gastric-inhibitory peptideand glucagonlike-peptide 1 receptors, have shown promise in managing blood sugar levels during Ramadan. Non-insulin-dependent medications like sodium-glucose-cotransporter-2 inhibitors, including the Food and Drug Administration-approved ertugliflozin, are also being used to provide additional cardiovascular benefits in patients with type 2 diabetes.
Clinical Characteristics of 802 Patients with Facial Palsy: Based on Literature Related to Stomach Meridian
Authors: Jin Dong-eun , Jang Soo-young , Shin Hyeon-cheol
Published: September 2023

Objectives: The purpose of this study was to suggest the clinical characteristics and risk factors of facial palsy from the perspective of Korean Medicine.Methods: Medical records of 856 patients, who visited the Korean Medicine hospital with facial palsy from 2004 to 2019, were retrospectively analyzed. The clinical characteristics of facial palsy were suggested by figuring out the distribution of age, sex, occupation, onset season, obesity, modes, signs, symptoms, past and family history.Results: By gender, there were more males (54.6%), and the most common age groups were in their 50s (27.4%) and 40s (23.6%). As for the occupation, unemployed (27.7%) and service and sales workers (14.6%) were the most common, and the onset season was the most common in winter (28.9%). The most common clinical characteristics were overwork (33.0%), mental stress (24.8%), and exposure to cold (19.3%) in modes, ‘none’ (64.3%), postauricular pain (33.2%) in signs, postauricular pain (26.9%), parageusia (14.8%) in symptoms. Hypertension and diabetes were the most common in both past and family history. In particular, the obesity rate of the subjects (59.8%) was much higher than that of Koreans (32.8%).Conclusions: Based on the historical Korean Medicine literature and the results of this study, it is suggested that overwork, stress, exposure to cold, and obesity are identified as risk factors for facial palsy. Furthermore, dysfunction of the stomach meridian is thought to contribute to the cause of facial palsy.
A Study on the Relationship Between Daeseunggi-tang and Sepsis
Authors: Lee Ju-Hyun , Jo Eun-Heui , Park Min-Cheol
Published: September 2023

Objectives: This research aims to analyze the relationship between Daeseunggi-tang and sepsis in literature.Methods: The main treatment symptoms of Daeseunggi-tang presented in Sanghanron and GeumGweyoryak, the symptoms of Ju-hwang and Nae-ham which correspond to sepsis in Korean Medicine, the symptoms of sepsis presented in the related papers including international guideline and diagnosis criteria of spesis were compared and analyzed.Results: The main treatment symptoms of Daeseunggi-tang were very similar to the symptoms of sepsis, and were almost identical to the symptoms of Ju-hwang and Nae-ham (especially Hwa-ham, Gu-ham), which are the Korean medicine descriptions of sepsis.Conclusions: Based on the above research results, it seems to be possible to use Daeseunggi-tang for the treatmentof sepsis.