bluuebunny/crossref_metadata_2025 huggingface dataset:
Is IGF-1 level actually lowered in the early stage following an acute myocardial infarction and is IGF-1 associated with the left ventricle dysfunction or cardiac events?
Authors: YILMAZ Yücel , TANRIVERDİ Fatih , DURAN Mustafa , ALTAY Mustafa , ERYOL Namık Kemal
Published: December 2019

Background: Insulin-like growth factor
(IGF) is the primary mediator of growth hormone. IGF-1 may have an important
role in protecting the myocardial functions following an acute myocardial
infarction (AMI). Literature reveals only a limited number of studies
investigating the relationship between the serum IGF-1/IGF binding protein-3 (IGFBP-3)
levels and the left ventricular functions post AMI.  We aimed to determine
IGF-1 and IGFBP-3 levels and evaluate their effect on cardiac functions post
AMI.Material and Method: Sixty five patients who were included
in the study and the control group had 26 patients. Blood samples of the
patients were obtained on the second day of their admission. The patients
underwent echocardiographic examination on the 7th day of their
hospitalization.Results: The serum IGF-1 and IGFBP-3 levels of the patient group were
higher than those of the control group; however only IGF-1 levels were
statistically significant (243,2±87,9 ng/mL versus 177,2±81,8 ng/mL p=0,001).
The increase in the wall thickness and LV chamber size did not correlate with
the decrease in LVEF and IGF-1/IGFBP-3 levels. The patients who had minor
cardiac events had lower IGF-1 levels but this was not statistically
significant (210.5±88.5 versus 253.1±86.1 p>0.05).

Conclusion: IGF-1 and IGFBP-3 levels elevated
following an the early AMI, but these markers were not correlated with the
echocardiographical measurements in early post MI period.
Three noninvasive methods in the evaluation of subclinical cardiovascular disease in patients with diabetic retinopathy: endothelial dysfunction, serum E-selectin level and monocyte to HDL ratio
Authors: KAN Seyfullah , KARAİBRAHİMOĞLU Adnan
Published: December 2019

ABSTRACTAim:
Cardiovascular
risk has increased in diabetic retinopathy (DR). Brachial artery flow mediated
dilation (FMD) is a non-invasive method used to evaluate endothelial
dysfunction. Measurement of adhesion molecules such as E-selectin is the
indirect method of predicting endothelial dysfunction. Monocyte/ HDL ratio
(MHR) is a novel marker found to be related with cardiovascular diseases. In
this study, in DR patients without an apparent cardiovascular disease, we aimed
to investigate the relation between endothelial dysfunction indicators such as
MHR, FMD, E-selectin and subclinical atherosclerosis.Material
and Method: In this study, 96 diabetic patients without apparent
cardiac symptoms and 32 healthy control patients that matched for gender, age
and body mass index (BMI) were included. The patients were separated into four
groups as; nonproliferative diabetic retinopathy (NPDR, n=31), proliferative
diabetic retinopathy (PDR, n=32), diabetic patients without a retinopathy
(n=33)  and control group (n=33).
Anthropometric, biochemical values and FMD were measured. Correlation and
regression analysis were done for the relation between MHR and FMD.Results: MHR was significantly high in PDR group
(p<.001). E-selectin and FMD which
are indicators for endothelial dysfunction were significantly different between
groups (p< .001). E-selectin measures
were highest in PDR group, lower in NPDR group, however it was significantly
higher than DM and control groups (p=
.026). Inversely proportional to E-selectin, FMD was significantly higher
in control and significantly lower in PDR group (p< .001). Univariate logistic regression method was used to
determine factors that had an influence on FMD. Glucose, HbA1C, CRP and MHR had
a negative effect.

Conclusion: In patients with DR, MHR levels
might be used as a novel non-invasive marker to determine early atherosclerotic
risk.
Mean platelet volume and platelet distribution width as mortality predictors in ıntensive care unit
Authors: GENÇAY İşın , BÜYÜKKOÇAK Ünase , ATEŞ Gökay , ÇAĞLAYAN Osman
Published: December 2019

Background
and Aim: This study aimed to determine the mean platelet volume (MPV) and
platelet distribution width (PDW) values of intensive care patients, and show
the relationship between these parameters and mortality. Material and Method: In the present study, 284 patients who were hospitalized in the intensive
care unit were retrospectively analyzed. MPV and PDW values of the patients
when they first hospitalized, their last MPV and PDW values before they died or
were discharged, their ages and duration of hospitalization were recorded. Results: There was
no significant difference between the MPV and PDW values in the group of the
patients who survived. Similarly, there was no statistically significant
difference between PDWFirst and PDWLast values in the group of the patients who
died (p> 0.05). However, MPVLast value increased significantly compared to
MPVFirst values (p <0.05) in the group of the patients who died. MPVLast was
found to be the most important factor when the age, hospitalization period, MPV
and PDW values of the patients, which are associated with mortality, were
compared.

Conclusion: This
study showed that MPV values increased in the patients who died and that they
were closely related to mortality.
Combined effect of gastrocnemius stretching with self-stabilising talus during subtalar supination on ankle kinematics in subjects with limited ankle dorsiflexion
Authors: Lee Jihyun , Cynn Heonseock , Park Donghwan
Published: December 2019

BACKGROUND:

Exercises that stretch the gastrocnemius (GCM) lead to greater ankle dorsiflexion (DF). GCM stretching combined with talar self-stabilisation has been reported to increase ankle DF range of motion (ROM). However, excessive subtalar and midtarsal pronation during GCM stretching may compensate for reduced ankle DF. Thus, this study examined the combined immediate effect of stretching GCM and stabilising talus and subtalar supination on limited ankle DF.

OBJECTIVE:

This study aimed to investigate the immediate effect of GCM stretching alone, GCM stretching with talar self-stabilisation and GCM stretching with talar self-stabilisation and subtalar supination on ankle kinematics in subjects with limited ankle DF.

METHODS:

Fifteen subjects with limited ankle DF were recruited. The subjects performed the three abovementioned methods.

RESULTS:

GCM stretching with talar self-stabilisation and subtalar supination significantly increased open-chain and closed-ankle DF ROM compared with GCM stretching alone. Moreover, GCM stretching combined with talar self-stabilisation and subtalar supination significantly increased open-chain ankle DF ROM with knee straight compared with pre-intervention ([Formula: see text] 0.017).

CONCLUSIONS:

The preferred method to increase ankle DF ROM is GCM stretching combined with talar self-stabilisation and subtalar supination.
Split ratio-based performance analysis method of PM-assisted reluctance machine
Authors: Yan Dong , Guo Liyan , Shi Tingna , Wang Huimin , Yan Yan , Xia Changliang
Published: December 2019

The split ratio is one of the most important design parameters of the machines and has a significant effect on the electromagnetic performance. Using the split ratio, this paper presents a performance analysis method for permanent magnet (PM)-assisted reluctance machine is presented. An accurate analytical model, which considers the saturation of outer iron ribs and the asymmetric saturation of rotor islands, is firstly proposed. In order to reduce the numbers of the adjustable structural parameters during the initial design process and ensure the independence among the parameters, a geometric structure corresponding to the split ratio is then established. The effectiveness of the proposed analytical model based on the split ratio is verified by FEM, and applied to analyze the electromagnetic performance for the three-flux-barrier PM-assisted reluctance machines. On the basis of the analysis results, the design scheme corresponding to the optimal split ratio, which makes the machine obtain a higher efficiency and guarantees the PMs without irreversible demagnetization, is determined rapidly.
ANALISIS KOTA JAKARTA SEBAGAI SMART CITY DAN PENGGUNAAN TEKNOLOGI INFORMASI DAN KOMUNIKASI MENUJU MASYARAKAT MADANI
Authors: Astutik Endang Puji , Gunartin Gunartin
Published: December 2019

ABSTRAKANALISIS KOTA JAKARTA SEBAGAI SMART CITY DAN PENGGUNAAN TEKNOLOGI INFORMASI DAN KOMUNIKASI MENUJU MASYARAKAT MADANI. Penelitian ini bertujuan untuk menganalisa dan mendeskripsikan perkembangan Jakarta Smart Cityter masuk keunggulan-keunggulan dan kekurangan dari  Jakarta Smart City yang dikaitkan dengan penggunaan teknologi informasi dan komunikasi untuk menuju masyarakat madani setelah berjalan empat tahun lebih. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan pendekatan analisa deskriptif. Penelitian ini menggunakan teknik analisa deskritif dari data yang telah dikumpulkan. Teknik pengumpulan data  menggunakan data sekunder  yaitu dari web site Jakarta Smart City Go. Id dan data primer melalui wawancara langsung dengan nara sumber yaitu divisi Jakarta Smart City (JSC). Hasil penelitian menunjukkan bahwa pelaksanaan komponen-komponen Jakarta Smart City seperti smart mobility, smart government, smart economy, smart environment, smart living dan smart people sudah berjalan baik serta sangat terintegrasi dengan penggunaan teknologi informasi. Demokrasi, toleransi, pluralisme juga sudah terlihat, keadilan sosial sedang diwujudkan dengan adanya perhatian Pemprov DKI terhadap rakyatnya. Begitu pula dengan berdirinya lembaga swadaya masyarakat, pers, dan partai politik bahwa setiap warga Jakarta berhak menyalurkan aspirasinya. Dari hasil penelitian dapat disimpulkan perkembangan Jakarta Smart City yang sekarang sudah baik, hubungan dengan penggunaan Teknologi Informasi sangat erat, sedangkan kekurangan dari Jakarta Smart City yaitu perkembangan inovasi teknologi informasi lebih cepat dibandingkan dengan regulasi artinya jika ada inovasi teknologi yang terkini belum bisa langsung dijalankan, harus melalui sistem regulasi anggaran. Tatanan Masyarakat Madani di kota Jakarta sudah terlihat dengan tandai banyaknya pembangunan wilayah publik yang luas serta bebas berpolitik tanpa adanya tekanan. Pemerintah, swasta dan masyarakat sudah terjalin kerjasama dalam pembangunan Jakarta yang lebih inovatif dan transparan. Kata Kunci : Smart City, Teknologi Informasi dan Komunikasi, Masyarakat Madani
Analisis SWOT Sebagai Perencanaan Desa Wisata Edukasi Agrikultur Cabe Dengan Pendekatan Konsep Pariwisata Berbasis Masyarakat di Desa Kabasiran, Parung Panjang, Kabupaten Bogor
Authors: Hapsari Andriyani , Mutawali Mutawali
Published: December 2019

Penelitan ini bertujuan untuk menganalisis peran dan potensi perusahaan, masyarakat, serta stakeholder lainnya dalam mengembangkan Desa Wisata serta merekomendasikan rencana dan strategi pengelolaan Desa Wisata. Penelitian ini menggunakan pendekatan kualitatif dengan metodologi riset aksi partisipatif. Diharapkan setelah pelatihan ini diperoleh gambaran tentang kondisi sosial ekonomi masyarakat serta rekomendasi strategi pengembangan dan pengelolaan Desa Wisata. Dari hasil Analisis SWOT yang dilakukan dapat disimpulkan bahwa Desa Wisata Edukasi Agrikultur Cabe perlu menerapkan strategi diversifikasi, karena berada dalam wilayah kekuatan dan ancaman. Diversifikasi harus dilakukan sebanyak mungkin, agar konsep pengembangan wisata ini bisa dikenal di masyarakat. Perlu adanya pembuatan edukasi, tempat wisata yang nyaman, dan produk olahan cabe yang unik.
Analisa Penentu Keputusan Pembelian Konsumen Analisa Penentu Keputusan Pembelian Konsumen Terhadap Produk Online (Pada Masyarakat Jabodetabek) Produk Online (Pada Masyarakat Jabodetabek)
Authors: Pratama Yuga
Published: December 2019

Penelitian ini  membahas tentang perilaku keputusan pembelian konsumen terhadap produk online. Penelitian ini bertujuan untuk:  (1) menentukan peringkat media e commerce dan  alasan penentu apa saja yang di gunakan  masyarakat Jabodetabek dalam mengambil keputusan pembelian atau belanja produk online, (2) mengetahui faktor faktor bauran pemasaran yaitu produk, promosi, harga, lokasi atau tempat dan promosi yang mempengaruhi keputusan pembelian produk online pada masyarakat di Jabodetabek.Penelitian ini menggunakan metode analisis regresi linier berganda dengan menggunakan aplikasi Stata 10. Populasi penelitian adalah seluruh masyarakat di Jabodetabek dengan sampel sebanyak 100 responden.Hasil dari penelitian ini bahwa 100 %  responden melakukan belanja online dengan alasan proses yang mudah dengan pilihan media e commerce 3 (tiga) peringkat teratas yaitu shopee, tokopedia dan lazada. Peringkat pertama produk yang menjadi pilihan masyarakat Jabodetabek adalah fashion yang meliputi baju, tas dan sepatu untuk digunakan secara pribadi dengan metode pembayaran yang paling sering digunakan adalah metode transfer antar bank.  Pada faktor- faktor bauran pemasaran yang mempengaruhi keputusan pembelian belanja online, hasilnya menunjukkan bahwa variabel proses dan promosi berpengaruh terhadap keputusan pembelian belanja online sedangkan produk, harga, lokasi dan people (manusia) tidak berpengaruh terhadap keputusan pembelian online di Jabodetabek
Analisa Brand Image Dalam Pengambilan Keputusan Memilih Perguruan Tinggi
Authors: Ningsih Dewi
Published: December 2019

Penelitian ini bertujuan untuk mengetahui citra merek yang terdapat di Universitas Pamulang, sehingga mampu mempengaruhi mahasiswa memilih Universitas Pamulang.Metode yang terdapat pada penelitian ini, peneliti menggunakan phenomenological method. Dalam pengumpulan data di penilitian ini peneliti menggunakan metode snowball sampling.Brand Image atau citra merek yang selama ini berusaha disampaikan kepada masyarakat luas sudah berhasil diterima. Seperti ketika masyarakat khususnya mahasiswa mendengar kata “Unpam” maka mereka langsung mengingat bahwa Universitas Pamulang merupakan Perguruan Tinggi memiliki harga terjangkau untuk semua lapisan masyarakat, memiliki fasilitas yang sangat baik seperti gedung yang besar, dan memiliki kualitas yang baik.Brand image dalam pengambilan keputusan mahasiswa memilih kampus sangat dipertimbangkan oleh mahasiswa, mereka memilih Perguruan Tinggi ini karena mempertimbangkan biaya yang harus dikeluarkan selama berkuliah, mereka melihat gedung yang sangat besar, dan mendengar rekomendasi dari teman – teman mereka bahwa Universitas Pamulang merupakan kampus yang berkualitas dibuktikan dengan saat ini memiliki Akreditas B pada program studi Manajemen S1.
Microaccelerometer on Surface Acoustic Waves with a Ring Resonator on Anisotropic Material
Authors: Lukyanov Dmitry P. , Boronakhin Alexander M. , Shevchenko Sergey Yu. , Khivrich Mariya A. , Amirov Temurmalik A.
Published: December 2019

Introduction. Diagnostic systems are designed to monitor the condition of operational components (for example, on the railway). It is imperative that micro-electromechanical systems (MEMS) equipped with acceleration sensors (accelerometers) be used as part of measuring diagnostic systems. It is known that accelerometers are operated under increased vibration and repeated shock loads. This imposes a limitation both on the accelerometer design and the properties of materials from which these devices are produced.

Aim. To develop a micromechanical accelerometer (MMA) for surface acoustic waves (SAW), capable of measuring shock effects.

Materials and methods. The theoretical part of the study was carried out using the mathematical theory of differential equations, theoretical mechanics, finite element analysis and elements of SAW theory. In the course of the work, the following methods of mathematical processing were applied: MATLAB, Mathcad, Maple, COMSOL Multiphysics, OOFELIE: Multiphysics, Bluehill3 software, CorelDRAW. Experimental studies were also conducted using the INSTRON 5985 floor automated test system.

Results. An original design of MMA on a SAW capable of measuring shock effects in hundreds of g was proposed. A sensing element (SE) of the sensor was developed. An analysis of the plate materials for their use as part of the SAW-based MMA design showed that SE from the quartz ST-cut material has a wider range of measured accelerations and a higher sensitivity threshold than SE from the YX-128˚ cut-off lithium niobate material. Requirements were developed to increase the SE sensitivity threshold. Design requirements were developed, and an interdigital transducer (IDT) topology in the form of a ring resonator was proposed. The following output characteristics were assessed: sensitivity threshold, dynamic range and scale factor. In addition, a procedure was developed for calculating MMA on a SAW with a ring resonator on an anisotropic material. It was found that the developed SE is characterized by a high sensitivity threshold, a wide dynamic range and a low transverse sensitivity.

Conclusion. The technique proposed for designing a sensing element for use in solid-state linear acceleration sensors facilitates, depending on technical requirements, selection of construction materials and sensor design. Due to the originality of the design and engineering solutions, the proposed accelerometer allows measurements to be carried out across a wide range of impact loads.
Experimental Study of K-Band Broadband Antenna Array Using Artificial Inhomogeneous Dielectric Structures
Authors: Aleksandrin Anton M. , Salomatov Yury P.
Published: December 2019

Introduction. As a result of the extensive development of broadband communication in the millimetre wave band, there has arisen a need for antenna systems with a high level of directivity and compact dimensions, capable of operating across wide frequency ranges. However, at present, few engineering solutions satisfy this demand.

Aim. To develop and study experimentally a K-band antenna array (AR) characterized by a high aperture efficiency and compact longitudinal dimensions.

Materials and methods. Computer simulations were performed using the CST Studio Suite software. Measurements were carried out using an Agilent E8363B PNA vector circuit analyzer. Radiation patterns were obtained by the method of near-field scanning.

Results. A K-band broadband antenna array configuration operating over the 18…26 GHz range was pro-posed. It was found that the period of the array equals 2.25 wavelengths at the highest operating frequency. In order to suppress grating lobes, an additional layer consisting of artificial inhomogeneous dielectric lenses was used. The dielectric material consisted of thin curly layers of sheet polyethylene terephthalate. Additionally, a hybrid configuration of feeding network was proposed, in which one part of the network was developed by means of printed two-wire lines, while the other part was achieved by means of rectangular waveguides. The proposed antenna array demonstrates VSWR of less than 2 and an aperture efficiency above 0.5, side and diffractive lobe levels not exceed –12 in the 18…26 GHz range. The total thickness of the configuration equals 50 mm or 4.3λmin. In order to ensure the compactness of the AR for wideband frequency applications, the thickness of the system can be reduced to 2.5λmin by excluding the waveguide part.

Conclusion. When compared with existing solutions, the proposed antenna has a simpler feed network, which yields better matching. High aperture efficiency is achieved in the wide frequency range by means of inhomogeneous dielectric lenses.
Modeling and Practical Implementation of a Broadband Double-Ridged Horn Antenna with an Operating Range More Than an Octave and a High Level of Cross-Polarization Discrimination
Authors: Meshcheriakov Viktor V. , Markova Natalia V. , Iurmanov Pavel D.
Published: December 2019

Introduction. The resolution of the problem of radio polarimetry in multiposition microwave screening systems (MMSS) with aperture synthesis requires the use of antennas with a high level of cross-polarization discrimination (XPD) in a wide spatial angle. The radio images are reconstructed in MMSS at distances commensurate with the aperture of the antenna structures. Therefore, the value of the spatial angle, at which high XPD is required, can reach 30°. This leads to a new problem of creating an antenna configuration of the X and Ku band, the application of which in MMSS will resolve the problem of constructing a radio image of depolarized microwave radiation scattered on the human body in the form of hidden dangerous objects.

Aim. To develop a double-ridged receiving antenna for long-term operation in MMSS with an XPD level of 28 dB at a spatial angle of 30° and operating frequencies of 8…20 GHz.

Materials and methods. The requirements for the receiving antenna in MMSS were determined. Theoretical justifications were proposed for the choice of antenna design. Aperture synthesis was used to construct microwave images in MMSS. The stages and results of modelling broadband double-ridge antennas were presented using the CST Studio software broadly applied for three-dimensional electro-magnetic field modelling. The results of modelling pyramidal and conical double-ridged antennas, as well as those in circular and elliptical waveguides, were analyzed. The designed antenna was tested in an anechoic chamber. The measurement results were compared with those obtained during simulation.

Results. An elliptical double-ridged horn antenna with a VSWR of no more than 2 and cross-polarization discrimination in a spatial angle of 30° of no less than 28 dB for the frequency range that covers an octave was designed and constructed.

Conclusion. The developed antenna can be used in MMSS for the purpose of detecting the effect of micro-wave radiation depolarization as hidden dangerous objects on a human body. Such characteristics of the antenna as its high XPD value in a wide spatial angle will allow the future introduction of microwave polarimetry in MMSS.
Method for Automatic Segmentation of Vehicles in Digital Images
Authors: Zubov Ilya G.
Published: December 2019

Introduction. Modern systems for active vehicle safety are designed to significantly reduce the number of road accidents. Sensors based on monocular cameras are increasingly being introduced by the world's leading automakers as an effective tool for improving traffic safety. Modern methods of localisation and classification, combined with semantic segmentation algorithms, allow for image division into independent groups of pixels corresponding to each object. However, the problem of developing segmentation algorithms ensuring improved quality of image segmentation remains to be solved.

Aim. To develop an automatic method for segmenting a given object during image analysis.

Materials and methods. An automatic method for segmenting vehicles in an image was proposed. The method presented herein allows semantic segmentation of the object of interest, based upon a priori information about the bounding boxes, which frame the objects in the image. Bounding box information is used to transform an image into a polar coordinate system where the pixels of the image act as the edges of a weighted graph. A closed contour is obtained around the object of interest by using the shortest path search algorithm and inverse transformation to the Cartesian coordinate system.

Results. The experiments confirmed the correctness of the selected area of interest based on this algorithm. Jacquard’s similarity coefficient for the Carvana open database is 85 %. Furthermore, the proposed method was applied to different classes of images from the Pascal VOC database, thus demonstrating the ability to segment objects of other classes.

Conclusion. The main contribution of the proposed method was as follows: 1) segmentation of the object of interest at the level of modern methods, and in some cases in excess thereof; 2) the study presents a new look at the way of tracking object contours.
From Gas Sensors to Detection of Etanol Vapour to Sensor of Bacteria Detection
Authors: Dimitrov Dimitre Tz.
Published: December 2019

Introduction. Metal oxide semiconductor sensors have many advantages. But their working temperature is still high and their sensitivities are frequently low. In the current work, I present the results from investigation of sensing ability of new kind of potentiometric solid state gas sensor.

Aim. The main goal of this work is investigation of the temperature dependence in the flow of air and in ethanol vapour mixture of the investigated junction structures. Also, we investigated at fixed temperature the dependence of the thermoelectric force from the ethanol vapour concentration at possible low operation temperature. For the structure, which shows the lowest operation temperature to ethanol vapour, we investigate the ability to detect Pseudomonas putida suspension.

Materials and methods. In this work, the sensitivity to ethanol vapour and Pseudomonas putida suspension were investigated by measuring the thermoelectric force (the voltage) appearing of the structures by standart voltmeters.

Results. Two experimental installations for sensors have been developed. The first one is for detection of ethanol vapour by ZnO/ZnO:Cu, ZnO/ZnO:CuO, ZnO/ZnO:Fe junction structures. The second installation was for Pseudomonas putida suspension detection in gas phase by ZnO/ZnO:Fe junction structure. We discovered that ZnO/ZnO:Fe structure, has the lowest operation temperature of 200 °C to ethanol vapour. For this structure, the potential difference has a negative value and decreases with increasing the amount of the pulverized bacteria.

Conclusion. We discovered that ZnO/ZnO:Fe structure, has the lowest operation temperature of 200 °C. This operation temperature is a bit higher than operation temperature of at which some very novel sensing structures shows the maximum sensitivity.
Fibromiyaljili Hastalarda D vitamini Düzeyi Hastalık Şiddeti ve Enflamatuar Göstergeler ile İlişkili midir?
Authors: TURGAY Türkan , GÜNEL KARADENİZ Pınar
Published: December 2019

Bu çalışmada fibromiyalji hastalarının D vitamini seviyeleri ile hastalık şiddeti ve enflamasyonla ilişkisini nötrofil lenfosit oranı (N/L), platelet lenfosit oranı (P/L), ortalama trombosit hacmi (OTH), eritrosit sedimentasyon hızı (ESH) ve C-reaktif protein (CRP) parametrelerini kullanarak değerlendirme ve klinik önemini araştırma amaçlanmıştır. Çalışmaya SANKO Üniversitesi Uygulama ve Araştırma Hastanesi Fizik Tedavi ve Rehabilitasyon Polikliniğine başvurmuş fibromiyaljili hastalar ve sağlıklı kontroller dahil edildi. Fibromiyalji hastalarının fonksiyonel durumunu değerlendirmek için Fibromiyalji Etki Anketi kullanıldı. Hastalara ait demografik ve laboratuvar bilgileri retrospektif olarak dosya taraması ile elde edildi. Fibromiyalji (n=51) ve kontrol (n=46) grubu arasında cinsiyet ve yaş bakımından istatistiksel olarak anlamlı bir fark yoktu (sırasıyla; p=1.000, p=0.074). Hasta ve kontrol gruplarının trombosit, OTH, nötrofil, lenfosit, N/L, P/L değerleri arasında istatistiksel olarak anlamlı bir fark bulunamadı (p>0.05). Fibromiyalji hastalarında D vitamini eksikliği, CRP ve ESH düzeylerinde-ki yükseklik istatistiksel olarak anlamlı bulunurken (sırasıyla p<0.001, p=0.009, p=0.036), D vitamini eksikliği ve hastalık şiddeti arasında anlamlı bir korelasyon bulunamadı (p=0.313). Her iki grupta D vitamini ve hastalık şiddeti ile diğer parametreler arasında da istatistiksel olarak anlamlı bir korelasyon saptanmamıştır (p>0.05). Çalışmamız her iki grupta D vitamini eksikliğinin hastalık şiddeti ve trombosit, OTH, N/L, P/L, ESH, CRP değerleri arasında anlamlı bir ilişki olmadığını ortaya koydu. Fibromiyalji sendromunda D vitamini ile enflamasyon belirteçlerinin ve hastalık şiddetinin arasındaki ilişkiyi değerlendirmek için daha geniş çaplı çalışmalara ihtiyaç vardır.
Yaşam Sonunun Uyarıcı İşareti: Kennedy Terminal Ülseri
Authors: ERBAY Öznur , ERARI Gülhan
Published: December 2019

Karen Lou Kennedy tarafından 1989 yılında tanımlanan, uzun süre bakım alan terminal hastalarda görülen Kennedy Terminal Ülseri (KTÜ), cilt dolaşımı yetersizliği nedeniyle hastanın ölümüne yakın saatler veya günler öncesinde ortaya çıkmakta ve hızlı bir şekilde ilerlemektedir. Ölüm sürecinin parçası olarak ortaya çıkan ve kaçınılmaz bir cilt krizi olarak nitelendirilen KTÜ, 2009 yılından bu yana Ostomi Yara Yöne-timi (Ostomy Wound Management) tarafından tanınmıştır. Ayrıca 2009 yılında uzmanlardan oluşan Yaşamın Sonunda Cilt Değişikliği konulu bir panelde (Skin Changes At Life’s End-SCALE), bu ülserin genellikle koksiks veya sakrumda görüldüğü ancak diğer anatomik bölgelerde de meydana geldiği ve genellikle ölüme yakın bir sürede görülme ile ilişkili olduğu bildirilmiştir. Bu özel sınıflandırmaya, 2014 yılında The Centers for Medicare & Medicaid Services (CMS) Uzun Süreli Bakım Hastanesi Kalite Programı Kılavuzu kapsamında da değinilmiştir. Klinik uzmanlar KTÜ'lerin nasıl tedavi edileceği konusunda farklı yaklaşımlara sahip olsalar da, mevcut literatürde multidisip-liner ekip yaklaşımının benimsenmesi gerektiği ve bu ekip içindeki yer alan hemşirelerin spesifik bakım müdahalelerinin önemi konusunda hemfikirdir. Bu derlemede sağlık profesyonellerinin KTÜ'lerin varlığına yönelik farkındalığı arttırmak, hastaya daha iyi destek verebilmeleri ve kaliteli bakım hizmeti sağlayabilmeleri için tanılanma ve tedavi seçeneklerini tartışmak amaçlanmıştır.
إمكانية تحول المصارف التقليدية إلى مصارف إسلامية في ليبيا
Authors: Alani Usama
Published: December 2019

هدف البحث إلى التعرف على إمكانية تحول المصارف التقليدية إلى مصارف إسلامية في ليبيا، من خلال استعراض تجربة المصارف التقليدية الليبية في تقديم منتجات الصيرفة الإسلامية، والوقوف على أهم المعوقات التي واجهت المصارف التقليدية للتحول للصيرفة الإسلامية في ليبيا. ولتحقيق أهداف البحث اتبع الباحثان المنهج الوصفي في إعداد الجانب النظري من البحث، والأسلوب التحليلي في إعداد الجانب العملي منه، حيث تم توزيع ) 70 ( استمارة على أفراد عينة البحث، وعند استردادها كانت ) 51 ( منها صالحة للتحليل والدراسة. وقد توصل البحث إلى أنَّ من أهم دوافع التحوّل في ليبيا كان قرار السلطة التشريعية في البلاد، إضافة إلى الرغبة الشعبية لدى المجتمع الليبي في تقديم المصارف منتجات متوافقة مع أحكام الشريعة الإسلامية. أوصى الباحثان بعدد من التوصيات منها: الإعداد لخطة شاملة لتحول المصارف التقليدية الراغبة في التحوّل للصيرفة الإسلامية تحت قيادة وإشراف مصرف ليبيا المركزي، من خلال التنسيق مع المصارف الراغبة في التحوّل. الكلمات المفتاحية: التحوّل، المصرف الإسلامي، المصرف التقليدي.
Legal Framework For Shariah Compliance of Moroccan Islamic Banks
Authors: Mechkour Anouar
Published: December 2019

Morocco has adopted, in 2014, a new banking regulation (law 103-12), which introduced a specific title related to Islamic banking. The new banking regulation gives the Higher Council of Ulema (HCU) the exclusive prerogative to set the rules and serve as the final arbiter for Shariah compliance of Moroccan Islamic banks. Further more, the law 103-12 requires Moroccan Islamic banks to create, within them, independent functions that will be responsible for ensuring compliance with the decisions and advices of the Supreme Council of Ulemas.In this paper, we provide an analytical study of the Sharia compliance modelintroduced by the Moroccan legislature for Moroccan Islamic banks. As such, the paper analyzes the basis of the choice made by the Moroccan legislature, the missions, roles and responsibilities of the different actors of the MoroccanShariah compliance model and, finally, its perspectives. A benchmark is also carried out in order to draw lessons from the best practices of other jurisdictions. The research main conclusion is that in spite of some gray areas that have tobe addressed by the legislature, the Moroccan model will allow developing national Shariah standards and ensure a perfect mitigation of conflict of interests. Furthermore, the Moroccan model will help participative banks to be cost-effective, mitigate reputation risk.
Powierzchniowe a wartościowe opodatkowanie nieruchomości na przykładzie Polski i Niemiec
Authors: Felis Paweł , Gołębiowski Grzegorz , Stiller Wojciech
Published: December 2019

Celem artykułu była ocena powierzchniowego i wartościowego opodatkowania nieruchomości na przykładzie Polski i Niemiec. W analizie odwołaliśmy się do teoretycznych koncepcji zawartych w literaturze oraz do innych badań, a także uwzględniliśmy takie kryteria, jak makroekonomiczna efektywność (znaczenie fiskalne), kwestie sprawiedliwości i neutralności oraz elementy techniczne. Zauważyliśmy większą istotność fiskalną opodatkowania nieruchomości w systemie katastralnym. Niemniej przeprowadzona przez nas analiza nie daje jednoznacznej odpowiedzi na pytanie, który system opodatkowania jest lepszy. Każdy z nich ma swoje zarówno mocne, jak i słabsze strony. Wybór zależy od czynników społecznych i decyzji politycznych, które mogą – ale nie muszą – być pochodną potrzeb finansowych jednostek samorządu terytorialnego.
Role of Morphological and Metalinguistic Awareness on Reading among Turkish EFL Learners
Authors: Akbulut Fatma Demiray
Published: December 2019

This study investigates the effect of morphological treatment on morphological awareness and reading comprehension skill in a foreign language teaching. Experimental design was used in this study which was conducted with 74 freshmen who are studying at Translation and Interpreting Department. Following the Oxford Quick Placement Test and Nation’s Vocabulary Knowledge Test, the participants were divided into two groups as experimental and control groups. Before starting the training process, both groups were pretested with ‘Morphological Correction Test (MCT)’ and ‘Reading Comprehension Test (RCT)’. Following the completion of the pre-test, the treatment period of experimental group for 2 semesters started, while the control group completed the same exercises and studies without focusing on the morphological awareness. Behind the training, post-test study was applied to both groups and the differences were analysed. According to the results, the experimental group outperformed the control group in MCT and RCT. In other words, the morphological awareness of the experimental group increased efficiently; in addition to this, their reading comprehension skills developed as well. Besides, it can be said that the participants benefited effectively and consciously from the explicit training period of morphological awareness and this helped them improve their metalinguistic capacity.
Reflexiones para una integración saludable de nuevos insectos en la dieta de los petirrojos (sobre museos, empresas y patrocino)
Authors: Mateos Rusillo Santos M.
Published: December 2019

Participación en el debate de revista PH 99
Programmable Ce6 Delivery via Cyclopamine Based Tumor Microenvironment Modulating Nano-System for Enhanced Photodynamic Therapy in Breast Cancer
Authors: Feng Chan , Chen Lv , Lu Yonglin , Liu Jie , Liang Shujing , Lin Yun , Li Yongyong , Dong Chunyan
Published: December 2019

Photodynamic therapy (PDT) has shown great promise in breast cancer treatment. However, simplex target ligand modification or stimuli release cannot meet the requirement of effective drug delivery to solid tumor tissue. To overcome continuous bio-barriers existing in the tumor microenvironment, multi-stage response drug delivery was desirable. Herein, we developed a unique tumor microenvironment tailored nanoplatform for chlorin e6 (Ce6) delivery. We chose bovine serum albumin (BSA) as “mother ships” material for effective tumor periphery resident, cyclopamine (CYC) as extracellular matrix (ECM) inhibitor and synergistic anti-tumor agent, and diselenide containing amphiphilic hyaluronic acid-chlorin e6 polymers (HA-SeSe-Ce6) synthesized as “small bombs” for internal tissue destruction. The above three distinct function compositions were integrated into an independent CYC and HA-SeSe-Ce6 co-delivery albumin nano-system (ABN@HA-SeSe-Ce6/CYC). The obtained nano-system presents good biocompatible, long circulation and effective tumor accumulation. After entering tumor microenvironment, CYC gradually releases to disrupt the ECM barrier to open the way for further penetration of HA-SeSe-Ce6. Subsequently, targeted tumor cell internalization and intracellular redox response release of Ce6 would achieve. Moreover, CYC could also make up the deficiency of Ce6 in hypoxia area, owing to its anti-tumor effect. Improved therapeutic efficacy was verified in a breast cancer cell line and tumor-bearing mice model.
Are Cry Studies Replicable? An Analysis of Participants, Procedures, and Methods Adopted and Reported in Studies of Infant Cries
Authors: Gabrieli Giulio , Scapin Giulia , Bornstein Marc , Esposito Gianluca
Published: December 2019

Infant cry is evolutionarily, psychologically, and clinically significant. Over the last half century, several researchers and clinicians have investigated acoustical properties of infant cry for medical purposes. However, this literature suffers a lack of standardization in conducting and reporting cry-based studies. In this work, methodologies and procedures employed to analyze infant cry are reviewed and best practices for reporting studies are provided. First, available literatures on vocal and audio acoustic analysis are examined to identify critical aspects of participant information, data collection, methods, and data analysis. Then, 180 peer-reviewed research articles have been assessed to certify the presence of critical information. Results show a general lack of critical description. Researchers in the field of infant cry need to develop a consensual standard set of criteria to report experimental studies to ensure the validity of their methods and results.
A Comparison Study of a Novel Self-Contained Electro-Hydraulic Cylinder versus a Conventional Valve-Controlled Actuator—Part 1: Motion Control
Authors: Hagen Daniel , Padovani Damiano , Choux Martin
Published: December 2019

This research paper presents the first part of a comparative analysis of a novel self-contained electro-hydraulic cylinder with passive load-holding capability against a state of the art, valve-controlled actuation system that is typically used in load-carrying applications. The study is carried out on a single-boom crane with focus on the control design and motion performance analysis. First, a model-based design approach is carried out to derive the control parameters for both actuation systems using experimentally validated models. The linear analysis shows that the new drive system has higher gain margin, allowing a considerably more aggressive closed-loop position controller. Several benefits were experimentally confirmed, such as faster rise time, 75% shorter settling time, 61% less overshoot, 66% better position tracking, and reduction of pressure oscillations. The proposed control algorithm is also proven to be robust against load variation providing essentially the same position accuracy. In conclusion, the novel self-contained system is experimentally proven to be a valid alternative to conventional hydraulics for applications where passive load-holding is required.
The Utility of the Upcoming HyspIRI’s Simulated Spectral Settings in Detecting Maize Gray Leafy Spot in Relation to Sentinel-2 MSI, VENµS, and Landsat 8 OLI Sensors
Authors: Sibanda Mbulisi , Mutanga Onisimo , Dube Timothy , Odindi John , Mafongoya Paramu L.
Published: December 2019

Considering the high maize yield loses caused by incidences of disease, as well as incomprehensive monitoring initiatives in crop farming, there is a need for spatially explicit, cost-effective, and consistent approaches for monitoring, as well as for forecasting, food-crop diseases, such as maize Gray Leaf Spot. Such approaches are valuable in reducing the associated economic losses while fostering food security. In this study, we sought to investigate the utility of the forthcoming HyspIRI sensor in detecting disease progression of Maize Gray Leaf Spot infestation in relation to the Sentinel-2 MSI and Landsat 8 OLI spectral configurations simulated using proximally sensed data. Healthy, intermediate, and severe categories of maize crop infections by the Gray Leaf Spot disease were discriminated based on partial least squares–discriminant analysis (PLS-DA) algorithm. Comparatively, the results show that the HyspIRI’s simulated spectral settings slightly performed better than those of Sentinel-2 MSI, VENµS, and Landsat 8 OLI sensor. HyspIRI exhibited an overall accuracy of 0.98 compared to 0.95, 0.93, and 0.89, which were exhibited by Sentinel-2 MSI, VENµS, and Landsat 8 OLI sensor sensors, respectively. Furthermore, the results showed that the visible section, red-edge, and NIR covered by all the four sensors were the most influential spectral regions for discriminating different Maize Gray Leaf Spot infections. These findings underscore the potential value of the upcoming hyperspectral HyspIRI sensor in precision agriculture and forecasting of crop-disease epidemics, which are necessary to ensure food security.
Contribution of Proximal and Distal Grains Within Spikelets in Relation to Yield and Yield Components in the Winter Wheat Production Region of China From 1948 to 2012
Authors: Feng Fan , Dang Pengfei , Pu Xuan , Wen Xiaoxia , Qin Xiaoliang , Chen Yinglong , H. M. Siddique Kadambot
Published: December 2019

Grain number and weight within a spikelet are major yield components which determine the grain yield in wheat. The objective of this study was to explore genetic gains in grain performance within wheat spikelets at the individual grain level and its effect on grain yield and evaluate genetic progress in stem internode length and other yield-related traits. We conducted field experiments across three growing seasons in the western Yellow and Huai Valley of China; incorporating 17 bread wheat cultivars released from 1948 to 2012. Yields were significantly correlated with year of release. Yield gains equated to 3.95 g m−2 yr−1 in response to increases in total grain weight per m2 (GW) in proximal (G1 and G2) and distal (G3 and G4) grains, despite a decline in the proportional contribution of proximal grains to yield and increase in the proportional contribution of distal grains to yield with year of release. Grain number per m2 (GN), thousand-grain weight (TGW), and harvest index (HI) increased with year of release, but plant height decreased. Both grain number per spikelet of proximal and distal grain contributed to the increase in total GN. However, the contribution ratio of GN in proximal grains to total GN declined, and the proportion in distal grains increased. Average single grain weight (SGW) increased linearly at G1, G2, G3, and G4 with year of release and contributed to the increase in TGW. The G3 and G4 grain positions had much lower individual grain weights but increased at a faster rate than G1 and G2. At G1, G2, and G3 grain positions, from bottom to top spikelets, the newly released cultivars had the heaviest grains and the old cultivars had the lightest grains. New cultivars had more spikelets than old cultivars and the number of grains (proximal and distal grains) in the apical spike increased with year of release. The length of five internodes decreased significantly with year of release, more so in the upper than lower internodes, all of which contributed to the decline in plant height. In summary, increasing the number and weight of distal grains could increase grain yield, TGW, and GN.
Winter Rye Cover Crop with Liquid Manure Injection Reduces Spring Soil Nitrate but Not Maize Yield
Authors: Everett Leslie A. , Wilson Melissa L. , Pepin Randall J. , Coulter Jeffrey A.
Published: December 2019

In maize-based cropping systems, leaching of nitrate-nitrogen (NO3-N) to drainage tile and groundwater is a significant problem. The purpose of this study was to assess whether a winter rye cover crop planted after silage maize or soybean harvest and injected with liquid manure could decrease soil NO3-N without reducing the yield of the following maize crop. An experiment was conducted at 19 sites with predominant occurrence of Mollisols (15 out of 19 sites) in the upper Midwest USA immediately after soybean or maize silage harvest to compare a drilled rye cover crop and a non-cover crop control. Later in the fall, liquid swine or dairy manure was injected into the cover crop and control plots. Rye was terminated the following spring using herbicide, usually before reaching 20 to 25 cm in height, and incorporated with tillage at most sites, after which maize was planted and harvested as silage or grain. Across sites, soil NO3-N at rye termination was reduced by 36% (range = 4% to 67%) with rye compared to no rye. Nitrogen in aboveground rye biomass at termination ranged from 5 to 114 kg N ha−1 (mean = 51 kg N ha−1). Across sites, there was no significant difference in yield of maize silage or grain between treatments. These results demonstrate in a Mollisol-dominated region the potential of a winter rye cover crop planted before manure application to effectively reduce soil NO3-N without impacting yield of the following maize crop, thereby reducing risk of negative environmental impacts.
Evaluation of the Antifungal Activity of the Licania Rigida Leaf Ethanolic Extract against Biofilms Formed by Candida Sp. Isolates in Acrylic Resin Discs
Authors: de Freitas Maria Audilene , Silva Alves Adryelle Idalina , Andrade Jacqueline Cosmo , Leite-Andrade Melyna Chaves , Lucas dos Santos Antonia Thassya , Felix de Oliveira Tatiana , dos Santos Franz de Assis G. , Silva Buonafina Maria Daniela , Melo Coutinho Henrique Douglas , Alencar de Menezes Irwin Rose , Bezerra Morais-Braga Maria Flaviana , Pereira Neves Rejane
Published: December 2019

Candida sp. treatment has become a challenge due to the formation of biofilms which favor resistance to conventional antifungals, making the search for new compounds necessary. The objective of this study was to identify the composition of the Licania rigida Benth. leaf ethanolic extract and to verify its antifungal activity against Candida sp. and its biofilms. The composition identification was performed using the ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) technique. The antifungal activity of extract and fluconazole against planktonic cells and biofilms was verified through the minimum inhibitory concentration (MIC) following biofilm induction and quantification in acrylic resin discs by reducing tetrazolic salt, with all isolates forming biofilms within 48 h. Six constituents were identified in the extract, and the compounds identified are derivatives from phenolic compounds such as flavonoids (epi) gallocatechin Dimer, epigallocatechin and gallocatechin, Myricetin-O-hexoside, Myricitrin, and Quercetin-O-rhamnoside. The extract reduced biofilm formation in some of the strains analyzed, namely C. tropicalis URM5732, C. krusei INCQS40042, and C. krusei URM6352. This reduction was also observed in the treatment with fluconazole with some of the analyzed strains. The extract showed significant antifungal and anti-biofilm activities with some of the strains tested.
Dissecting the Antimicrobial Composition of Honey
Authors: Nolan Victoria C. , Harrison James , Cox Jonathan A. G.
Published: December 2019

Honey is a complex sweet food stuff with well-established antimicrobial and antioxidant properties. It has been used for millennia in a variety of applications, but the most noteworthy include the treatment of surface wounds, burns and inflammation. A variety of substances in honey have been suggested as the key component to its antimicrobial potential; polyphenolic compounds, hydrogen peroxide, methylglyoxal and bee-defensin 1. These components vary greatly across honey samples due to botanical origin, geographical location and secretions from the bee. The use of medical grade honey in the treatment of surface wounds and burns has been seen to improve the healing process, reduce healing time, reduce scarring and prevent microbial contamination. Therefore, if medical grade honeys were to be included in clinical treatment, it would reduce the demand for antibiotic usage. In this review, we outline the constituents of honey and how they affect antibiotic potential in a clinical setting. By identifying the key components, we facilitate the development of an optimally antimicrobial honey by either synthetic or semisynthetic production methods.