bluuebunny/crossref_metadata_2025 huggingface dataset:
Characteristics of antibiotics and antibiotic resistance genes in Qingcaosha Reservoir in Yangtze River Delta, China
Authors: Xu Ting , Zhao Wanting , Guo Xueping , Hu Shuangqing , Zhang Hongchang , Huang Zhifeng , Yin Daqiang
Published: January 2020

Background Aquatic ecosystems are considered to be among the most important reservoirs of antibiotic resistance genes (ARGs). Drinking water sources were usually parts of lakes and rivers in Yangtze River Delta, among which Qingcaosha Reservoir is the largest river impoundment and benefit the population of more than 13 million for Shanghai city. In this study, we aimed at investigating the distribution of antibiotics and ARGs to characterize the pollution across various sites in Qingcaosha Reservoir in three seasons.Results Sulfamethoxazole, sulfamonomethoxine and penicillin G potassium salt were the dominant antibiotics and of high detection frequencies in this reservoir. Sulfonamide resistance genes ( sul1 and sul2 ) were the most prevalent and predominant genes. Higher total relative abundance of the ARGs were detected in the site closest to the inflow than those in other sites. Overall, the concentrations of antibiotics in May (spring) were relatively lower than November (autumn) and February (winter). Correlation analysis indicated sul1 , ermB and mphA had positive correlation with corresponding antibiotics in February and intI1 was also greatly positively correlated to sul1 , sul2 , ermB and mphA .Conclusion In conclusion, the antibiotics and ARGs were widespread in Qingcaosha Reservoir. Our result indicated that the drinking water reservoir might serve as gene reservoir for antibiotic resistance and mobile gene element intI1 can serve as a medium to contribute to the widespread of various ARGs. What is more, we considered that Reservoir could be served as a functional area contributing to the elimination of ARGs.
Simultaneous adsorption study of ammonium and phosphate by ZnFe-layered double hydroxide (ZnFe-LDH)-modified adsorbents.
Authors: Liu Feng , LIANG XINQIANG , Li Hua , Jin Yingbing , Zhang Chuxuan , Wang Ziwan , Tian Guangming
Published: January 2020

Background Trace amounts of nitrogen and phosphorus can easily trigger eutrophication damage in surface water, while cost-effective adsorption treatment is in prospect for clearing these pollutants simultaneously and efficiently. In this study, engineered adsorbents decorated with ZnFe-LDH by alkaline coprecipitation (3-6 mm, with modified ceramsite as CZF and modified volcanic rock as VZF) were prepared for NH 4 + and H 2 PO 4 - co-adsorption from aqueous solutions.Results Coexisting ions showed great effects on phosphate adsorption, especially Ca 2+ and CO 3 2- , and humic acid exhibited only a limited shielding impact on co-adsorption properties. Though comprehensive tests presented that the maximum captured amount of ammonium and phosphate occurred at pH 7, the isotherm and kinetic results suggest that two adsorbents preferentially adsorbed each pollutant. Specifically, the maximum uptake quantity of NH 4 + (15.55 mg-N g -1 ) and H 2 PO 4 - (11.21 mg-P g -1 ) were achieved by VZF and CZF, respectively, and controlled by physisorption and chemisorption distinctively, revealing that contaminants were cleared in disparate ways. Performances of seven consecutive adsorption/desorption cycles using 5% NaOH regenerant suggested that CZF retained 71.9% of PO 4 - removal efficiency, and VZF retained 47.9% of the NH 4 + adsorption rate, implying the strong reusability of ZnFe-LDH-modified adsorbents. A dynamic study has assessed that with 1 kg of combined modified adsorbents, approximately 527 L of polluted runoff flow could be continuously treated to below the National limits within one adsorption cycle.Conclusion Comparing with other parallel adsorbents, ZnFe-LDH-modified adsorbent is promising in eliminating eutrophication due to their superior capacity, stability, renewability, and non-toxicity.
Decoding the differentiation of mesenchymal stem cells into mesangial cells at the transcriptomic level
Authors: Wong Chee-Yin , Chang Yao-Ming , Tsai Yu-Shuen , Ng Wailap Victor , Cheong Soon-Keng , Chang Ting-Yu , Chung I-Fang , Lim Yang-Mooi
Published: January 2020

Background: Mesangial cells play an important role in the glomerulus, providing mechanical support to it, and maintaining efficient ultrafiltration of renal plasma. Loss of mesangial cells due to pathologic conditions may lead to impaired renal function. Mesenchymal stem cells (MSC) have been reported can differentiate into many cell types, including mesangial cells. However transcriptomic profiling during MSC differentiation into mesangial cells had not been studied yet. The aim of this study is to examine the pattern of transcriptomic changes during MSC differentiation into mesangial cells as well as to understand the involvement of transcription factor (TF) along the differentiation process, and finally to elucidate the relationship among TF-TF and TF-key gene or biomarkers during the differentiation of MSC into mesangial cells. Methods: Differentiation of MSC into mesangial cells was induced by co-culturing with injured mesangial cells. Total RNA from co-cultured MSC were extracted before running RNA sequencing. Generated RNA-seq data was analysed by two methods simultaneously: 1) Monotonic Feature Selector (MFSelector) to identify the key genes with ascending and descending monotonic patterns, and 2) Time-Ordered Gene Co-expression Network (TO-GCN) to construct a TF co-expression network. Results: MFSelector has identified several monotonic key genes (either ascending or descending). These identified descending monotonic key genes are related to stemness or regulation of cell cycle while ascending monotonic key genes are associated with the functions of mesangial cells. The TFs were arranged in a co-expression network in order of time by TO-GCN analysis. Additionally, not only can TO-GCN analysis classify the differentiation process into three stages: differentiation preparation, differentiation initiation and maturation, but it can also explore TF-TF-key genes regulatory relationships in the muscle contraction process. Conclusions: A systematic analysis for transcriptomic profiling of MSC differentiation into mesangial cells has been established. Key genes or biomarkers, TFs and pathways involved in differentiation of MSC-mesangial cells have been identified and the related biological implications have been discussed. Finally, we further elucidated for the first time the three main stages of mesangial cell differentiation, and the regulatory relationships between TF-TF-key genes existing in the muscle contraction process.
Theoretically designed interventions for colorectal cancer prevention: A Case of the Health Belief Model
Authors: Rakhshanderou Sakineh , Ghaffari Mohtasham , Safari-Moradabadi Ali , Maghsoudloo Maryam
Published: January 2020

Background According to the WHO, most chronic diseases, including cancer, can be prevented by identifying their risk factors such as unhealthy diet, smoking and physical inactivity. This study examined the effectiveness of educational interventions on colorectal cancer prevention-nutritional behaviors by employing a health belief model among the personnel of Shahid Beheshti University of Medical Sciences.Methods In this experimental study, 110 employees of Shahid Beheshti University of Medical Sciences were randomly divided into two groups (intervention and control) with cluster sampling. The data gathering tool was a researcher-made questionnaire containing two parts of 10-dimensional information and health belief model constructs. Educational intervention was conducted for one month and in four sessions in the form of classroom lecture, pamphlet, educational text messages via mobile phones and educational pamphlets through the office automation system. Two groups were evaluated in two stages, pre-test and post-test. Data were analyzed using SPSS-18 software, paired t-test and independent t-test (intergroup comparisons).Results Two groups were evaluated for variables such as age, sex, education level and family history of colorectal cancer, and there was no significant differences between the two groups (P <0.05). After the two months since intervention, except for the mean score of perceived barriers, which was not significant after intervention, the mean scores of knowledge, perceived susceptibility, perceived severity, perceived benefits, perceived self-efficacy, behavioral intention, and preventive behaviors were significantly increased after the intervention in the intervention group compared to the control group (P> 0.05).Conclusion Implementation of educational intervention based on health belief model was effective for the personnel, and can enhance the preventative nutritional behaviors related to colorectal cancer.
Longitudinal observation of OCT imaging is a valuable tool to monitor primary vitreoretinal lymphoma treated with intravitreal injections of methotrexate
Authors: Zhao Huiying , Wang Xiaona , Mao Yu , Peng Xiaoyan
Published: January 2020

Background: Developing objective and repeatable indicators to evaluate the efficacy of PVRL treatment is important. The quantification of vitreous cells is a traditional criterion; however slight changes are difficult to ascertain. Spectral domain optical coherence tomography (SD-OCT) is objective, repeatable, and easily explained. The purpose of this study is to provide a longitudinal observation of OCT in PVRL treated with intravitreal injections of methotrexate (MTX) and to evaluate the utility of OCT in monitoring responsiveness of PVRL to treatment. Methods: The medical records of patients with biopsy-positive PVRL attending our hospital between January 2016 and September 2017 who received intravitreal injections of MTX were included in this study. Pre- and post-treatment OCT images were reviewed independently by two researchers. Results: Of the 24 cases reviewed, 10 patients (18 eyes) were included. SD-OCT abnormalities at the initial visit included vitreous cells (18/18), OR (outer retina) fuzzy borders (12/18), PED (pigment epithelium detachments) (9/18), subretinal hyperreflective infiltration (3/18), intraretinal infiltration (8/18), and SRF (subretinal fluid) (4/18). Post induction treatment, SRF in cases with RD (retinal detachment) was absorbed, and subretinal fibrosis appeared. Other lesions were significantly reduced. Post consolidation treatment, OR fuzzy borders, PED and SRF disappeared in 2 eyes, intraretinal infiltration disappeared in 1 eye, and other abnormalities further improved. Additionally, retinal fibrosis was observed in 3 eyes. One month post maintenance treatment, all abnormalities observed at the first visit vanished. At the last visit, OCT showed subretinal fibrosis and in 3 eyes (16.7%), the disruption of outer retina in 9 eyes (50%) and thinning of the whole layer in 4 eyes (22.2%). Conclusions: Our observations reveal that characteristic OCT features in PVRL patients can reduce gradually and finally vanish with therapy. We propose that SD-OCT may be employed to monitor the responsiveness of PVRL to treatment, which may influence decision making in the management of this disease.
Design, Synthesis and Cytotoxic Activity of Spiro(oxindole-3-3'- pyrrolidine) Derivatives
Authors: Konyar Dilan , Andac Cenk A. , Buyukbingol Erdem
Published: January 2020

Background:

Spiro[pyrrolidine-3,3'-oxindole] compounds are reported to be highly
bioactive natural and synthetic products. Initially, spirooxindole alkaloids were isolated from plants
of the Apocynaceae and Rubiaceae families, which were found to have a common scaffold,
spiro[pyrrolidine-3,3'-oxindole], exhibiting anticancer activities., we specifically aimed at the synthesis,
characterization and anticancer activity of novel spiro[pyrrolidine-3,3' -oxindole] derivatives,
compounds 6a-c and 7.

Methods:

The synthesis was initiated by Knovenegal condensation of indole-2-one with an appropriate
benzaldehyde in presence of piperidine to afford compounds 3a-c. Compounds 6a-c were
synthesized by an asymmetric 1,3-dipolar cycloaddition between compounds 3a-c and (2S, 3R)-2,
3, 5, 6-tetrahydro-2, 3-diphenyl-1, 4-oxazin-6-one, which is an intermediate compound formed by
the Schiff base reaction between 3-methyl-butanal and (2S, 3R)-2, 3, 5, 6-tetrahydro-2, 3-diphenyl-
1,4-oxazin-6-one, in presence of molecular sieves (4Å) under argon atmosphere. Compound 6a was
then reacted with ethylamine-HCl in THF at room temperature to yield compound 7.

Results:

Cytotoxic effects of the compounds synthesized were determined on Huh7, MV, HCT116
and MCF7 cancer cell lines by the NCI-60 Sulforhodamine B Assay, using (S)-(+)-Camptothecin as
a positive control. In general, target compounds showed better cytotoxic activities against the
MCF7 and HCT116 cancer cell lines. It was found that compound 7 exhibited the most potent inhibitory
activity with IC50 values of 4.8 µM, 3.9 µM, 14.9 µM and 8.2 µM against the MCF7,
HCT116, MV and Huh7 cell lines, respectively.

Conclusion:

It was determined that compounds 6a&6b possess C6'(S)|C8'(R)|C9'(R) stereochemistry
and compound 7 adopts C2'(S)|C4'(R)|C5'(R) stereochemistry. Cytotoxicity studies suggest that
compound 7 gave rise to the highest anticancer activity against MCF7, HCT116, and Huh7 cancer
cell lines.
Melhor do que o silêncio: o show e a música de João Gilberto
Authors: Duarte Pedro
Published: January 2020

Este artigo foi escrito após o show de João Gilberto apresentado no dia 24 de agosto de 2008, no Teatro Municipal do Rio de Janeiro. Narrando os acontecimentos do show, o artigo elabora sua interpretação sobre o procedimento artístico de João Gilberto. Sua abordagem, contudo, não é a da crítica musical técnica, mas, antes, a de certa crítica da cultura com viés filosófico.
β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1
Authors: Thomaidou Sofia , Kracht Maria J.L. , van der Slik Arno , Laban Sandra , de Koning Eelco J. , Carlotti Francoise , Hoeben Rob C. , Roep Bart O. , Zaldumbide Arnaud
Published: January 2020

The signal peptide of preproinsulin is a major source for HLA class I autoantigen epitopes implicated in CD8 T cell (CTL)–mediated β-cell destruction in type 1 diabetes (T1D). Among them, the 10-mer epitope located at the C-terminal end of the signal peptide was found to be the most prevalent in patients with recent-onset T1D. While the combined action of signal peptide peptidase and endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) is required for processing of the signal peptide, the mechanisms controlling signal peptide trimming and the contribution of the T1D inflammatory milieu on these mechanisms are unknown. Here, we show in human β-cells that ER stress regulates ERAP1 gene expression at posttranscriptional level via the IRE1α/miR-17-5p axis and demonstrate that inhibition of the IRE1α activity impairs processing of preproinsulin signal peptide antigen and its recognition by specific autoreactive CTLs during inflammation. These results underscore the impact of ER stress in the increased visibility of β-cells to the immune system and position the IRE1α/miR-17 pathway as a central component in β-cell destruction processes and as a potential target for the treatment of autoimmune T1D.
PAKAIAN PANGULU DI NAGARI GUNUANG KOTA PADANGPANJANG PROVINSI SUMATERA BARAT
Authors: Anwar Robi , Sastra Andar Indra , Zebua Edward
Published: January 2020

AbstrakPenelitian ini mendiskripsikan tentang bentuk pakaian pangulu. Fokus penelitian ini adalah pakaian pangulu di Nagari Gunuang Kota Padangpanjang provinsi Sumatera Barat. Pakaian pangulu merupakan pakaian kebesaran seorang pemuka adat suatu kaum yang menyandang gelar pangulu. Pakaian pangulu mencerminkan nilai kewibawaan seorang pemimpin yang terlihat secara visual. Metode dalam penelitian ini menggunakan pendekatan kualitatif dengan tipe deskriptif. Teknik pengumpulan data dilakukan dengan studi pustaka, observasi, dan dokumentasi. Penelitian ini membahas tentang bentuk dan makna pakaian pangulu. Hasil tentang pakaian pangulu berupa pakaian adat untuk seorang pemimpin adat di Nagari Gunuang Kota Padangpanjang. Pakaian itu terdiri dari destar/saluak, baju hitam longgar/baju gadang, kain sandang/salempang, celana/sarawa, sarung/sisampiang, ikat pinggang/cawek, keris/karih, tongkat/tungkek. Makna dari pakaian pangulu adalah wibawa seorang pemimpin kaum dalam mengayomi anak kemenakan dan mampu menjadi hakim pada masyarakat.Kata Kunci: pakaian, pangulu, bentuk, makna.AbstractThis study describes the form of pangulu clothing. The focus of this research is pangulu clothing in Nagari Gunuang, Padangpanjang, West Sumatra province. Pangulu clothing is an oversized clothing of an adat leader, a people bearing the title pangulu. Pangulu's clothes reflect the dignity of a leader visually. The method in this study uses a qualitative approach with descriptive type. The technique of data collection is done by literature study, observation, and documentation. This study discusses the shape and meaning of pangulu clothing. The results of the pangulu clothing in the form of traditional clothing for a traditional leader in Nagari Gunuang, Padangpanjang City. The clothes consist of a sash/saluak, loose black clothes/gadang clothes, clothing/salempang cloth, pants/sarawa, sarongs/sisampiang, belts / cawek, keris/karih, sticks/tungkek. The meaning of pangulu's clothing is the authority of a leader of the people in protecting the children of nephews and being able to be judges in the community..  Keywords: clothes, pangulu, shape, meaning.
KESESUAIAN POLA CELANA SISTEM CHARMANT PADA WANITA DEWASA INDONESIA BERTUBUH IDEAL
Authors: Hanifah Hanifah , Ernawati Ernawati
Published: January 2020

AbstrakTujuan penelitian untuk mendeskripsikan kelemahan, cara memperbaiki, serta kesesuaian pola celana wanita sistem Charmant terhadap wanita bertubuh ideal Indonesia. Metode penelitian yang digunakan adalah penelitian terapan. Objek penelitian yaitu pola celana wanita sistem Charmant yang diuji cobakan pada wanita bertubuh ideal Indonesia, dengan tinggi 165 cm, berat 57 kg. Dinilai oleh 5 orang panelis yang ahli dibidang pola busana wanita. Instrumen penelitian yang digunakan adalah kuesioner/angket memakai skala likerts. Teknik analisa data menggunakan statistik deskriptif berupa perhitungan rumus persentase menggunakan microsoft exel. Hasil penelitian menunjukkan pola celana wanita sistem Charmant terhadap wanita bertubuh ideal Indonesia, mempunyai 2 kelemahan berdasarkan penilaian dari 5 orang panelis diantaranya yaitu: 1) lingkar duduk sempit 4 cm, 2) tinggi duduk panjang 3 cm. Cara memperbaikinya yaitu: 1) lingkar duduk ditambahkan 1 cm pada pola depan dan belakang, 2) tinggi duduk dikurangi sebanyak 3 cm.Kata Kunci: kesesuaian, celana, charmant, wanita ideal.AbstractThe purpose of this study is to describe the weaknesses, how to improve, and the suitability of Charment’swomen's skrit pattern towards ideal Indonesian female posture. The method uses applied study. The data analysis was performed using descriptive statistics in the form of calculating formula percentages using Microsoft Excel. The object of this study was the Charmant’s women skirt pattern which were tested on an ideal Indonesian female posture, with a height of 165 cm, weight of 57 kg. Judged by 5 panelists who are experts in women's clothing. The study instrument was a questionnaire / questionnaire using the Likerts scale. The results showed that the Charmant’swomen skirt pattern towards an ideal Indonesian female posture had 5 weaknesses based on the assessment from 5 panelists which were : 1) circumference narrow sitting of 3 cm, 2) sitting high over 3 cm. How to improve it are: 1 cireumference  narrow sitting add by 1 cm on the front and back side, 2) sitting high shortened by 3 cm. Keyword: suitability, skirt, charmant, ideal woman posture.
PENGARUH MORDAN TAWAS DAN CUKA TERHADAP HASIL PEWARNAAN ECO PRINT BAHAN KATUN MENGGUNAKAN DAUN JATI (Tectona Grandis)
Authors: Masyitoh Fitri , Ernawati Ernawati
Published: January 2020

AbstrakPenelitian ini dilatar belakangi sebagai upaya pemanfaatan pewarna alam daun jati untuk membuat motif tekstil dengan teknik pewarnaan eco print yang ramah lingkungan. Penelitian ini bertujuan untuk mendeskripsikan nama warna (Hue), gelap terang (Value) dan kejelasan bentuk yang dihasilkan dari pewarnaan eco print bahan katun menggunakan daun jati (Tectona grandis) dengan mordan tawas dan cuka. Jenis penelitian ini merupakan penelitian eksperimen. Jenis data berupa data primer.pewarnaan eco print dengan mordan tawas menghasilkan nama warna Pomdadour Purple, warna kurang terang dan kejelasan bentuk termasuk kategori sangat jelas. Pada pewarnaan eco print dengan mordan cuka menghasilkan nama warna Muddy Waters Brown, warna terang dan kejelasan bentuk termasuk kategori cukup jelas.  Kata Kunci: eco print, daun jati, mordan.AbstractThis research is motivated as an effort to use natural teak leaf dyes to make textile motifs with eco-friendly coloring techniques. This study aims to describe the color name (Hue), dark darkness (Value) and the clarity of the shape resulting from the staining of eco print cotton using teak leaves (Tectona grandis) with mordan alum and vinegar. This type of research is experimental research. The type of data in the form of primary data. Eco print staining with mordan alum produces the color name Pomdadour Purple, the color is not bright and the clarity of the shape, including the category is very clear. On eco print staining with mordan vinegar produces Muddy Waters Brown color name, bright color and shape clarity including the category is quite clear..  Keywords: ecoprint, teak leaves, mordant.
THE IMPLEMENTATION OF DRILL EXERCISE VARIATIONS IN BASKETBALL LECTURING (CHEST PASS TECHNIQUE) AT THE STUDENTS OF PHYSICAL EDUCATION IN UNIVERSITY OF DEHASEN BENGKULU
Authors: Juniardi Arifto , Wibowo Tito Parta
Published: January 2020

This study aimed to improve the results of basketball chest pass learning which had a low success rate. Based on the above problems, it was necessary to make improvements in the lecture process, so that the learning outcomes target reached the KKM score. The success of lecturing was when the KKM value set by the study program achieved. The type of research was classroom action research with research subject students who took part in basketball lectures and lecturers who taught basketball courses. The population in this study was the Physical Education Study Program at FKIP University of Dehasen Bengkulu, the sample was the Physical Education Study Program for Semester V Class A1. Chest pass was given at the beginning of the lecture, but students still had difficulties in demonstrating chest passes. Thus this matter was considered important to improve the learning outcomes. This research was conducted on the basis of the level of success of students in basketball lectures was still low when without variations in drill exercise. In this study there was 1 colleague as an observer who was in charge of providing assessment and all findings from observers were discussed together to find out how to solve problems in the process of improving the results of basketball chest pass learning. The results of this study indicated that through the application of variations in drill exercise there was an increase in the results of physical education students' FK basketball chest pass at the University of Bengkulu FKIP. Based on this conclusion, the application of variations in drill exercise was recommended as an additional teaching concept in Basketball lecture.
DIR/FLOORTIME UNTUK MENINGKATKAN KOMUNIKASI ANTARA ANAK DENGAN AUTISME DAN IBU DENGAN PROFIL SENSORI BERBEDA
Authors: Isnannisa Ezra Dessabela , Boediman Lia Mawarsari
Published: January 2020

Kesulitan menjalin komunikasi adalah salah satu fitur utama pada Autism Spectrum Disorder (ASD). Anak dengan ASD cenderung memiliki gangguan pemrosesan sensori yang berdampak pada defisit kemampuan komunikasi. Hal tersebut membuat anak membutuhkan bantuan pengasuh untuk meregulasi diri sebelum dapat menjalin komunikasi dengan orang lain. Salah satu intervensi yang membantu meningkatkan kemampuan komunikasi adalah Developmental, Individual Differences, Relationship (DIR)/Floortime. Intervensi ini mempertimbangkan keunikan profil sensori dan perkembangan functional emotional partisipan sebagai landasan pembuatan program, serta melibatkan pengasuh secara aktif. Secara lebih lanjut, penelitian ini bertujuan untuk mengevaluasi efektivitas DIR/Floortime untuk meningkatkan komunikasi antar anak usia 4 tahun 2 bulan dengan autisme dan ibu dengan profil sensori yang berbeda.  Penelitian ini menggunakan single case design dan multiple baselines across situations untuk mengevaluasi penerapan DIR/Floortime pada situasi free dan semi-structured play. Lembar Observasi Circle of Communication (CoC) digunakan untuk menghitung jumlah komunikasi dua arah yang terjalin antara anak dan ibu. Skor kapasitas perkembangan functional emotional anak dan ibu juga diukur menggunakan Functional Emotional Assesment Scale untuk mengetahui kapasitas perkembangan yang melandasi kemampuan komunikasi. Hasil penelitian mengindikasikan bahwa DIR/Floortime efektif untuk meningkatkan jumlah dan kualitas komunikasi antara anak dan ibu. Setelah intervensi, anak lebih sering melakukan kontak mata, melakukan inisiasi dan respons verbal, serta tampak lebih engaged dalam berinteraksi bersama ibu. Keterlibatan aktif ibu dalam intervensi membuat ibu langsung merasakan perubahan positif pada anak saat berinteraksi. Hal tersebut memotivasi ibu yang sebelumnya cenderung pasif dalam berinteraksi untuk lebih dapat mengikuti minat dan tingkat keaktifan anak.
Efektivitas Program Peningkatan Keterampilan Dukungan Kemandirian pada Pengasuh Anak Usia Toddler Di TPA X
Authors: Rahmanissa Ulfa , Indianti Wahyu
Published: January 2020

Penelitian ini bertujuan untuk melihat efektivitas pelatihan Dukungan Kemandirian dalam meningkatkan keterampilan pengasuh dalam mendukung kemandirian anak usia 18 - 36 bulan di TPA X. Pelatihan yang dilakukan pada penelitian ini menggunakan dasar experiental learning, pelatihan diberikan kepada 29 pengasuh yang bekerja di 3 cabang TPA X. Pemilihan subjek menggunakan teknik accidental sampling. Pelatihan ini dilakukan sebanyak 5 sesi dalam waktu 2 hari. Penelitian ini merupakan penelitian dengan one group pre-test post-test design, yakni hanya memiliki satu kelompok perlakukan tanpa kelompok kontrol. Instrumen penelitian yang digunakan pada pretest dan post-test mengukur keterampilan dukungan kemandirian yang mengadopsi dari 18 praktik dukungan kemandirian Côté-Lecaldare yang kemudian dirancang oleh peneliti. Hasil pre-test dan post-test 1 diuji dengan non prametric Wilcoxon Signed Rank menunjukkan level signifikansi p.value 0,000 (<0,05). Perilaku stabil hingga post-test 2, uji non parametric Wilcoxon Signed Rank pada pre-test dan post-test 2 menunjukkan level signifikansi p.value 0,000 (<0,05). Hasil tersebut menunjukkan terdapat perbedaan yang signifikan antara hasil pre-test dengan post-test 1 dan post-test 2. Dengan demikian dapat disimpulkan bahwa pelatihan Dukungan Kemandirian efektif dalam meningkatkan  keterampilan dukungan kemandirian pengasuh terhadap anak usia toddler.
Relationship between self-directed learning readiness, learning attitude, and self-efficacy of nursing undergraduates
Authors: Meng Li-Na , Zhang Xiao-Hong , Lei Meng-Jie , Liu Ya-Qian , Liu Ting-Ting , Jin Chang-De
Published: January 2020

Objective

The purposes of this study were to analyze the influencing factors of self-directed learning readiness (SDLR) of nursing undergraduates and explore the impacts of learning attitude and self-efficacy on nursing undergraduates.

Methods

A total of 500 nursing undergraduates were investigated in Tianjin, with the Chinese version of SDLR scale, learning attitude questionnaire of nursing college students, academic self-efficacy scale, and the general information questionnaire.

Result

The score of SDLR was 149.99±15.73. Multiple stepwise regressions indicated that academic self-efficacy, learning attitude, attitudes to major of nursing, and level of learning difficulties were major influential factors and explained 48.1% of the variance in SDLR of nursing interns.

Conclusions

The score of SDLR of nursing undergraduates is not promising. It is imperative to correct students’ learning attitude, improve self-efficacy, and adopt appropriate teaching model to improve SDLR.
Technological models of development and their applicability to a Baltic states
Authors: Chaplygin Vladimir
Published: January 2020

Purpose – To study the possibilities of a theory to establish a modern theory of economic growth, including the factors of institutions and changes in technologies. These factors are a set of rules with high coercive force to the agents’ action, which form a particular mode/model of their adaptation, together with other institutions.

Findings – The research results may enrich an economic theory and practice in the area of business models applicability in Lithuania, Latvia and Estonia. The findings may assist an economic community to influence the general technological development within the national institutional systems.

Practical implications –The so-called institutional macroeconomics as a practical discipline (which has a very close connection with behavioural macroeconomics) may assist to explore the economic growth in a Baltic States from the point of view of changing institutions (firms, business community), labour markets and information.
EXPLORING VEGETABLE FARMING IN PERI-URBAN AREAS OF JAKARTA (A CASE STUDY OF TANGERANG REGENCY)
Authors: Fahmi Faisal
Published: January 2020

The presence of vegetable farmers in peri-urban areas is essential for the supply of food to the urban population. However, they face intense competition from other non-agricultural activities. This research aims to explore the characteristics of vegetable farmers in Tangerang Regency as part of Jakarta Metropolitan Area, the motivation of respondents towards becoming vegetable farmers, and their strategy in adapting to massive urban development. We employed the qualitative approach by combining questionnaires, field observations, and interviews. We found the new entrant farmers that are in their productive ages and came with experience in the formal economy before starting farming. The motivation of respondents became vegetable farmers vary depend on their background and the land ownerships. Farmers in the study area are doing diversification by having off-farm activities and doing intensification by patterning crop to adapt rapid urbanization. To sustain the development of vegetable farming in peri-urban area, it will be crucial for government to create the new strategy of using vacant lands as farmlands to produce vegetables in order to combat food security issues, and also to assist farmers by upgrading their skill through various trainings.Keywords: Peri-urban, Strategy, Vegetable Farming.
An Unstable Okun’s Law, Not the Best Rule of Thumb
Authors: Meyer Brent , Tasci Murat
Published: January 2020

Okun’s law is a statistical relationship between unemployment and GDP that is widely used as a rule of thumb for assessing the unemployment rate—why it might be at a certain level or where it might be headed, for example. Unfortunately, the Okun’s law relationship is not stable over time, which makes it potentially misleading as a rule of thumb.
Pengembangan Permainan Tradisional Lompat Tali Untuk Meningkatkan Kinestetic Intelegency Pada Anak Usia 11-12 Tahun
Authors: Rahayu Ervin Dwi , Firmansyah Guntur
Published: January 2020

Penelitian yang dilakukan peneliti bertujuan untuk membuat permainan tradisional lompat tali yang menarik, aman dan mudah dimainkan serta diharapkan bisa membantu untuk meningkatkan kinestetic intelegency pada anak usia 11-12 tahun. Metode yang digunakan adalah model pengembangan yang mengacu pada model pengembangan (research and development) Borg dan Gall. Hasil dari evaluasi ahli diperoleh data ahli pembelajaran 88,3 % dan ahli permainan tradisional 79,2 % sedangkan pada tahapan ujicoba diperoleh data pada ujicoba kelompok kecil dan kelompok besar diperoleh data 80,83% dan 83,33 %. Kesimpulannya pengembangan permainan tradisional lompat tali untuk meningkatkan kinestetic intelegency  pada anak usia 1-12 tahun bermanfaat, menarik, mudah, aman, efektif serhingga dapat diartikan dapat digunakan.
Uniformity and difference of ageing
Authors: Grgas Stipe
Published: January 2020

The author proposes that ageing and old age can be seen as a universal process but also as something that can be differentiated both by time and place. In the central part of the article, the author contends that one way of approaching the topic, particularly if it is addressed as part of the United States polity, is through the lens of American Studies and, more specifically, through the work of R.W.B. Lewis and his idea of the American Adam. It is precisely the self-image of the United States as a country of youth that elides the significance of ageing from the disciplinary agenda. In addition, the author contends that the American socio-economic order marginalizes ageing as incompatible with its dynamics. In the onclusion, the author up dates the issue and shows how today’s pension schemes affect what as precisely designated as a time of retirement.
DETERMINATION OF OCCUPATIONAL SAFETY CULTURE ON THE CULTURE OF PATIENT SAFETY CULTURE: THE CASE OF ELAZIG
Authors: Turan DEMİREL Erkan , GÜNDOĞDU Gülşen , Emül Eda
Published: January 2020

Çalışan sağlığı ve güvenliği, insan kaynakları yönetimi sürecinin en önemli unsurlarından birini oluşturmaktadır. Hasta güvenliği ise kaliteli sağlık hizmeti sunumunun temel göstergelerindendir. Hem hasta güvenliği hem de çalışan sağlığı ve güvenliği, hastanelerde verimliliği de artırmaktadır. Hastanelerin bu sonuçları elde edebilmeleri için hem yöneticilerin hem de çalışanların güvenliğe öncelik vermeleri gerekmektedir. Bu konuda, tüm paydaşlarına kararlı tutum göstermesi ve sorumluluk üstlenmesi beklenmektedir. Bu çalışma, iş güvenliği kültürünün hasta güvenliği kültürü üzerinde belirleyici olduğu iddiasına görgül destek sağlamak amacıyla yürütüldü. Bu amaçla, Elazığ il merkezinde yer alan kamuya ve özel sektöre ait tüm hastanelerin çalışanları ana kütle kabul edilerek veri toplandı. Veri toplamada anket tekniğinden yararlanıldı. Anket formunda Williamson’a ait “Güvenlik Kültürü Ölçeği (27 madde)”, Sorra ve Nieva’ya ait “Hasta Güvenliği Kültürü Ölçeği (42 madde)” ve demografik özelliklerle ilgili sorular (6 soru) yer aldı. Ana kütlede Şubat 2018 itibarıyla toplam 3479 sağlık çalışanı yer almaktaydı. Hastanelere dağıtılan 540 anket formundan 330’u geri alınabildi ve 313 anket formu değerlendirilebildi. Araştırma sonucunda katılımcıların hem iş güvenliği kültürü algılarının (ao=3,38; ss=0,45) hem de hasta güvenliği kültürü algılarının (ao=3,09; ss=0,40) vasat düzeyde olduğu tespit edildi. İş güvenliği kültürü algısının hasta güvenliği kültürü üzerindeki belirleyici etkisinin ise pozitif yönde ve vasat olduğu belirlendi. İş güvenliği kültürünün hasta güvenliği kültürü üzerinde %25 oranında etkili olabildiği görüldü [r=0,503; r2=0,251;
NEW INTERMEDIATE FORMS IN ELDERLY SOCIALIZATION
Authors: DEMİR Sevim ATİLA
Published: January 2020

Günümüz dünyasında her alanda olduğu gibi sosyalleşme alanında da önemli değişimler yaşanmaktadır. Bunlardan biri de sosyal dayanışmanın biçiminin ve niteliğinin değişmesidir. Günümüzde yüz yüze etkileşim alanları sosyalleşmeyi ve
dayanışma ihtiyacını destekleyecek biçimi ile neredeyse sadece çekirdek aile ağları ile sınırlanmıştır. Bu nedenle modern toplumlarda sosyalleşmenin yeni biçimlerini görmekteyiz. Bunların başında sosyal medya ve sanal topluluklar
yer alır. Dünyadaki yaşlı nüfusun her geçen yıl biraz daha artış göstermesi yaşlılık çalışmalarını daha önemli bir disiplin haline getirmişti. Yaşlılık çalışmaları sadece yaşlıların fiziksel ve ekonomik iyilik hallerine değil aynı
zamanda sosyal ve psikolojik iyilik hallerine de odaklanmaktadır. Yaşlılara yönelik çalışmaların aktif ve yerinde yaşlanmayı merkeze alarak yapılması bunun en önemli göstergelerinden biridir. Ancak buna rağmen teknolojik değişimlerin
hızı ve yeni gelişmeler özellikle sosyal anlamda yaşlıların yeni duruma uyum sağlamalarını güçleştirebilmektedir. Değişen iletişim ağlarının niteliği yaşlıların dayanışma ve kabul görme ihtiyaçlarının karşılanmasında bazı güçlüklerin
doğmasına yol açmıştır. Yerine geçen sanal destek ağları özellikle ülkemizde yaşlılar tarafından aktif olarak kullanılmamakta bu durum ise bazı psikolojik ihtiyaçların daha güçlü hissedilmesine yol açmaktadır. Modern toplumlarda
özellikle yaşlıların sosyalleşmesine yönelik yeni formlar gerekmektedir. Sosyal danışman, psikolog ve çeşitli kurumlar bünyesinde yaşlılara yönelik destekler vardır. Bu destek ağını genişletebilmek özellikle yaşama bağlılığı ve
sosyal desteği artırabilmek için önemlidir. Dünyada çeşitli biçimlerde var olan sosyal destek grupları bunun bir örneğidir. Modern toplumlardaki bahsedilen değişim alanları tüm bireyler için farklı ihtiyaçları gündeme getirmiştir.
Bu ihtiyaçlar yaşa, sosyo-ekonomik düzeye ve bireysel deneyimlere göre farklılaşmaktadır. Bu gruplar kişilerin farklılıklarını ve hassasiyetlerini dikkate alarak kurgulanmıştır. Sosyal destek grupları üzerine yapılan çalışmalar
hem destek grup organizasyon biçimleri hem de destek alanları yönü ile sınıflandırılmaktadır. Yaşlılık döneminde ailenin ve arkadaşların kaybedilmesi, sağlığın kötüleşmesi, hareketlilik ve gelir azalması gibi yaşlanmayla birlikte
sık yaşanan durumlar, yaşlı bireylerin daha da yalnızlaşmasına yol açabilmektedir. Yalnızlaşma umutsuzluk düzeyinin de artışı anlamına gelmekte ve beraberinde fiziksel zorluklarla mücadele gücü zayıflamaktadır. Özellikle kurumlarda
kalan yaşlılara yönelik daha çok dışarıdan gönüllü katılımlar teşvik edilerek düzenlenecek haftalık gruplar farklı ve yeni bir soluk olması açısından etkileşim alanları oluşturabileceği düşünülmektedir. Bu programların yaşlıların
sosyalleşmesinde yeni bir form olarak tartışılabilmesi önemli görülmektedir.
RESEARCH ON SELF SUFFICIENCY OF THE STUDENTS FOR PIANO COURSES IN PROFESSIONAL MUSIC EDUCATION IN TERMS OF DIFFERENT VARIABLES
Authors: BULUT Damla , ÜNAL Betül
Published: January 2020

Araştırmanın amacı, mesleki müzik eğitimi alan öğrencilerin piyano dersine yönelik öz yeterliklerini farklı değişkenler açısından incelemektir. Bu amaç doğrultusunda araştırmada eğitim fakültesi, devlet konservatuvarı ve güzel sanatlar fakültelerinin ilgili programlarında mesleki müzik eğitimi alan 1., 2., 3. ve 4. sınıf düzeyindeki öğrencilerin piyano dersine yönelik öz yeterliklerinin öğrenim görülen üniversite, fakülte, yaş, cinsiyet ve mezun olunan lise türü değişkenleri açısından farklılık gösterme durumu tespit edilmiştir. Araştırma tarama modelinde, betimsel bir alan araştırmasıdır. Araştırmanın evrenini Türkiye’de mesleki müzik eğitimi veren üniversitelerin 1., 2., 3. ve 4. sınıf öğrencileri, örneklemini ise 2017-2018 eğitim öğretim yılında basit rastgele örneklem seçme yöntemiyle belirlenen Niğde Ömer Halisdemir, Yüzüncü Yıl ve Harran Üniversitesi Müzik Eğitimi Anabilim Dallarının; Akdeniz, Atatürk ve Nevşehir Hacı Bektaş Veli Üniversitesi Güzel Sanatlar Fakültelerinin; Afyon Kocatepe, Selçuk, Kafkas Üniversitesi Devlet Konservatuvarlarının 1., 2., 3. ve 4. sınıf düzeylerinde müzik eğitimi alan 550 öğrenci oluşturmaktadır. Araştırma ile ilgili veriler Kurtuldu ve Bulut (2016) tarafından geliştirilen “Piyano Dersine Yönelik Öz Yeterlik Ölçeği” kullanılarak toplanmıştır. Araştırma bulguları doğrultusunda mesleki müzik eğitimi alan öğrencilerin öz yeterlik puanları ile ölçeğin alt boyutuna yönelik öz yeterlik puanlarının öğrenim görülen üniversite, yaş, cinsiyet ve mezun olunan lise türü değişkeni açısından anlamsal farklılık gösterdiği; öğrenim görülen fakülte, öğrenim görülen sınıf düzeyi değişkeni açısından anlamsal farklılık göstermediği sonuçlarına ulaşılmıştır.
Rol del profesional de enfermería en terapias de reemplazo renal, diálisis peritoneal
Authors: Licht-Ardila Maricel
Published: January 2020

Introducción: La enfermedad renal crónica es considerada un problema de salud pública en el ámbito mundial, debido a su prevalencia e incidencia creciente en la población. El profesional de enfermería asiste al paciente con su patología de base e integra a la familia en la realización de actividades que contribuyen al cuidado y prevención de la enfermedad o a la recuperación de su salud, por lo que el rol principal está orientado a ayudar al paciente, a conservar o lograr su independencia y generar en él hábitos de autocuidado de acuerdo con las necesidades identificadas. Objetivo: Esta revisión busca identificar el rol de Enfermería en el tratamiento de la terapia de reemplazo renal: diálisis peritoneal, con base en lo reportado en bases de datos durante el periodo 2008-2014. Metodología: Se realizó búsqueda sistemática de información en las bases de datos Scientific Library (Scielo), Medical Literature Analysis and Retrieval System Online (MEDLINE), PubMed, Proquest, Biblioteca Virtual en Salud, haciendo uso de los términos: “Cuidado de enfermería”, “Insuficiencia renal crónica”, “Diálisis peritoneal” y “Autocuidado” publicados en el periodo de 2008 a 2014. Conclusiones: Los documentos consultados señalan que el rol de Enfermería  predominante en el manejo de diálisis peritoneal es el educativo, pues se evidencia que con una adecuada instrucción y preparación al paciente y su cuidador se logra mayor adherencia al tratamiento y disminución de las complicaciones propias de la diálisis peritoneal. [Licht M, Almeida J, Bolívar F, Galván Y, García S. Rol del profesional de Enfermería en terapias de reemplazo renal, diálisis peritoneal. MedUNAB 2014; 17 (2): 107-113].
Ciencia, innovación y competitividad empresarial ¿Sobrevivirá Colciencias?
Authors: Useche-Aldana Bernardo Ignacio
Published: January 2020

La Ley 1753 del 9 de junio de 2015 por la cual se promulgó el Plan Nacional de Desarrollo 2014 – 2018 (PND) contiene en cinco artículos (artículos 5º, 7º, 10º, 12º, y 186º) una reforma estructural del Sistema Nacional de Ciencia, Tecnología e Innovación (SNCTI) en Colombia (1). Si bien es cierto, los lineamientos básicos estaban ya esbozados en el Plan Nacional de Desarrollo 2010 - 2014 y el énfasis en la de por sí precaria generación de conocimiento científico se había sustituido por la innovación empresarial desde 1995 con la creación del Sistema Nacional de Innovación y luego con la Ley 1286 de 2009; no se había definido de una manera tan radical como lo hace el actual PND, el que la dirección y el eje mismo del sistema de CTI no descanse ya en el Estado representado en Colciencias, ni en las universidades, ni en los centros de investigación públicos o privados, sino en las empresas a través de “las Comisiones Regionales de Competitividad en cada departamento” (art. 186 PND).
IMPLEMENTASI PEMBINAAN KEPRIBADIAN DI LEMBAGA PEMASYARAKATAN (Implementation Of Personality Development In The Correctional Institutions)
Authors: Ridwan Moch
Published: January 2020

Karya tulis ini menyoroti masalah implementasi pembinaan kepribadian Narapidana pada Lembaga Pemasyarakatan. Sejak tahun 1990-an, Direktorat Jenderal Pemasyarakatan (Kementerian Hukum dan Hak Asasi Manusia R.I.) masih menghadapi kompleksitas hambatan dalam implementasi Pemasyarakatan. Hal ini membuka cara lain dalam usaha memadukan sistem, pola dan program pelaksanaan pembinaan kepribadian terhadap Narapidana dengan wacana baru dalam pemidanaan yang lebih berkualitas. Populasi penelitian ini adalah Unit Pelaksana Teknis Pemasyarakatan, menggunakan metode survey dengan deskriptif, sedangkan pengambilan sampelnya dengan sample enumeration (judgement sample). Stagnansi pembinaan yang terjadi diantaranya diakibatkan karena model pembinaan saat ini belum direvisi dan dirancang sesuai dengan kekhususan kejahatan yang menjadi perhatian nasional dan internasional. Rekomendasi penelitian ini adalah perlunya diterbitkan Peraturan Pemerintah, untuk mengembangkan pembinaan di Unit Pelaksana Teknis Pemasyarakatan dengan standar pembinaan pemasyarakatan yang dapat memuat: standar isi, standar proses, standar Pembina dan Pembimbing Pemasyarakatan, standar sarana dan prasarana, standar pengelolaan, standar pembiayaan; dan standar penilaian.AbstractThis writing highlights implementation of personality development in the correctional institutions. Since the 1990s, Directorate General of Correctional (the Ministry of Law And Human Rights)has still faced the complexity of problems in its implementation. This has opened another way to integrate system, pattern and implementation program of personality development to convicts with new discourse in criminalization more qualified. The population of this research is the technical units of correctional. Collecting data by survey method and it is an analysis descriptive, whereas its sample is judgment sampling. Right now, stagnancy of development caused by its model has not revised and designed accordance with a certain of crime that become a concern, nationally and internationally.Recommendation of this research is important to issue government regulation to promote development of convicts in technical units of correctional with standard that consists of contents standard, process standard, standard of coach and Probation Officer, standard of infrastructure, management standards, financing standards, and assessment standards
Pengaruh Putusan Mahkamah Konstitusi No. 77/PUU-XII/2014 terhadap Pemberantasan Money Laundering Perbandingan Indonesia dengan Tiga Negara Lain
Authors: Ramdan Ajie
Published: January 2020

Money laundering adalah upaya untuk mengaburkan asal usul harta kekayaan dari hasil tindak pidana sehingga harta kekayaan tersebut seolah-olah berasal dari aktivitas yang sah. Apakah tindak pidana tersebut dapat berdiri sendiri atau tindak pidana yang bergantung pada tindak pidana yang lain? Artikel ini mengkaji pembuktian kejahatan money laundering dengan kajian yuridis normatif dan menganalisa Putusan MK No. 77/PUU-XII/2011 dengan menggunakan studi komparatif kejahatan money laundering di Negara Indonesia, Belanda, Inggris, dan Amerika Serikat. Putusan MK tersebut memperkuat dasar hukum bagi penegak hukum untuk menegakan hukum pidana dalam hal memberantas money laundering. Kesimpulannya kejahatan money laundering tidak dapat berdiri sendiri. Perbandingan kejahatan money laundering Indonesia, Belanda, Inggris dan Amerika menyimpulkan bahwa Kejahatan money laundering bukan merupakan tindak pidana asal. Demi terciptanya Equality Before The Law seharusnya Pemerintah dan DPR merevisi UU No. 8 Tahun 2010. Dalam praktik pemberantasan kejahatan money laundering di Indonesia seharusnya penegak hukum memperhatikan asas presumption of innocent.
Efficient Comparative Analysis Of Fertilizers Palm Oil
Authors: Febriadi Bayu , Anisya Anisya , Putra Pandu Pratama
Published: January 2020

Palm oil is a vegetable oil-producing plant that has more advantages compared to other vegetable oil-producing plants, which have high productivity reaching 4 tons ha-1 Crude Palm Oil (CPO). Palm oil is also a raw material for making food and non-food ingredients, and renewable fuels. The author wants to make an analysis by comparing two methods, namely the AHP Method (Analytical Hierarchy Process) and Fuzzy logic which is able to handle the uncertainty and uncertainty used. Fuzzy logic used is the Fuzzy Tsukamoto inference system because this method uses monotonous value applications, the output of the inference output from each rule is explicitly given (crisp) based on α-predicate (fire strength). Whereas the AHP Method can facilitate in calculating the validity to the tolerance level of concentration as criteria and alternatives chosen by the user.