bluuebunny/crossref_metadata_2025 huggingface dataset:
The association between short-term temperature variability and mortality in Virginia
Authors: Pane Melanie M. , Davis Robert E.
Published: September 2024

The objective of this study is to determine the relationship between short-term temperature variability on neighboring days and mortality. The change in maximum temperature in Northern Virginia, Richmond, Roanoke, and Norfolk, Virginia, on neighboring days was calculated from airport observations and associated with total mortality over a multi-county area surrounding each weather station. The association between day-to-day temperature change and mortality, lagged over a 28-day period, was analyzed using distributed lag non-linear models that controlled for air quality, temporal trends, and other factors. Days following large temperature declines were associated with an increased risk of mortality in three of the four locations, and temperature increases were linked to higher mortality risk in two cities. For example, the relative risk of mortality for a 12°C daily temperature decline (1st percentile) was 1.74 [0.92, 3.27] in Roanoke and 1.16 [0.70, 1.92] in Richmond. The net effect of short-term temperature increases was smaller, with the largest relative risk of 1.03 [0.58, 1.83] for a 12°C increase (99th percentile) in maximum temperature in Norfolk. In Richmond and Roanoke, there was an observed lagged effect of increased mortality (maximum relative risks varying from 1.08 to 1.10) that extended from 5 to 25 days associated with large temperature declines of 15°C or more. In contrast, there was a strong and immediate (lag 0–3 day) increase in the risk of mortality (1.10 to 1.15) in northern Virginia and Norfolk when the temperature increase exceeded 10°C (short-term warming). In general, consecutive day warming had a more immediate mortality impact than short-term cooling, when the peak mortality is lagged by one week or more. However, cooling of at least 10°C after a hot (summer) day reduced mortality relative to comparable cooling following a cold (winter) day, which is associated with high mortality. This differential mortality response as a function of temperature suggests that there is some relationship between average temperature, temperature variability, and season. The findings of this study may be useful to public health officials in developing mitigation strategies to reduce the adverse health risks associated with short-term temperature variability.
Additional predictors of stroke and transient ischaemic attack in BEFAST positive patients in out-of-hours emergency primary care
Authors: van Royen Florien S. , Geersing Geert-Jan , Erkelens Daphne C. , Delissen Mathé , Rutten Jorn V. F. , Zwart Dorien L. , van Smeden Maarten , Rutten Frans H. , van Doorn Sander
Published: September 2024

Introduction

In patients suspected of stroke or transient ischemic attack (TIA), rapid triaging is imperative to improve clinical outcomes. For this purpose, balance-eye-face-arm-speech-time (BEFAST) items are used in out-of-hours primary care (OHS-PC). We explored the risk of stroke and TIA among BEFAST positive patients calling to the OHS-PC, and assessed whether additional predictors could improve risk stratification.

Methods

This is a cross-sectional study of retrospectively gathered routine care data from telephone triage tape-recordings of patients calling the OHS-PC with neurological deficit symptoms, classified as BEFAST positive. Four models–with the predictors age, sex, a history of cardiovascular or cerebrovascular disease, and cardiovascular risk factors–were fitted using logistic regression to predict the outcome stroke or TIA. Likelihood ratio testing was used to select the best model, which was subsequently internally validated.

Results

The risk of stroke or TIA diagnosis was 52% among 1,289 BEFAST positive patients, median age 72 years, 56% female sex. Of patients with the outcome stroke/TIA, 24% received a low urgency allocation, while 92% had signs or symptoms when calling. Only the addition of age and sex improved predicting stroke or TIA (internally validated c-statistic 0.72, 95%CI 0.69–0.75). The predicted risk of stroke or TIA remained below 20% in those aged below 40. Females aged 70 or over and males aged 55 or over, had a predicted risk above 50%.

Discussion

Urgency allocation appears to be suboptimal in BEFAST positive patients calling the OHS-PC. Risk stratification could be improved in this setting by adding age and sex.
Symmetric nonlinear solvable system of difference equations
Authors: Stević Stevo , Iricanin Bratislav , Kosmala Witold
Published: September 2024

We show the theoretical solvability of the system of difference equations

x

n
+
k

=

y

n
+
l

y
n

−
c
d

y

n
+
l

+

y
n

−
c
−
d

,

y

n
+
k

=

x

n
+
l

x
n

−
c
d

x

n
+
l

+

x
n

−
c
−
d

,

n
∈

N

0

,
where
k
∈

N

,

l

∈

N

0

,
l
<
k
,
c
,
d
∈

C

and

x
j

,

y
j

∈

C

,
j
=

0
,
k
−
1

¯

. For several special cases of the system, we give some detailed explanations on how some formulas for their general solutions can be found in closed form, that is, we show their practical solvability. To do this, among other things, we use the theory of homogeneous linear difference equations with constant coefficients and the product-type difference equations with integer exponents, which are theoretically solvable.
Existence and uniqueness of Carathéodory and Filippov solutions for discontinuous systems of differential equations
Authors: López Pouso Rodrigo , Rodríguez-López Jorge
Published: September 2024

We use essential limits inferior and superior of the nonlinear part of a discontinuous ODE to introduce some novel transversality conditions which imply that Filippov solutions are Carathéodory solutions. We also prove some uniqueness criteria based on different Lipschitz conditions on different parts of the domain separated from one another by boundaries which satisfy certain transversality conditions.
Normalized solutions for Schrödinger equations with potential and general nonlinearities involving critical case on large convex domains
Authors: Wang Jun , Yin Zhaoyang
Published: September 2024

In this paper, we study the following Schrödinger equations with potentials and general nonlinearities

{

−
Δ
u
+
V
(
x
)
u
+
λ
u
=

|

u

|

q
−
2

u
+
β
f
(
u
)
,

∫

|

u

|

2

d
x
=
Θ
,

both on

R

N

as well as on domains

Ω
r

where

Ω
r

⊂

R

N

is an open bounded convex domain and
r
>
0
is large. The exponent satisfies
2
+

4
N

≤
q
≤

2
∗

=

2
N

N
−
2

and
f
:

R

→

R

satisfies

L
2

-subcritical or

L
2

-critical growth. This paper generalizes the conclusion of Bartsch et al. in [4]. Moreover, we consider the Sobolev critical case and

L
2

-critical case of the above problem.
Positive solutions for concave-convex type problems for the one-dimensional
ϕ
-Laplacian
Authors: Kaufmann Uriel , Milne Leandro
Published: September 2024

Let
Ω
=
(
a
,
b
)
⊂

R

,
0
≤
m
,
n
∈

L

1

(
Ω
)
,
λ
,
μ
>
0
be real parameters, and
ϕ
:

R

→

R

be an odd increasing homeomorphism. In this paper we consider the existence of positive solutions for problems of the form

{

−
ϕ

(

u

′

)

′

=
λ
m
(
x
)
f
(
u
)
+
μ
n
(
x
)
g
(
u
)

 in 
Ω
,

u
=
0

 on 
∂
Ω
,

where
f
,
g
:
[
0
,
∞
)
→
[
0
,
∞
)
are continuous functions which are, roughly speaking, sublinear and superlinear with respect to
ϕ
, respectively. Our assumptions on
ϕ
,
m
and
n
are substantially weaker than the ones imposed in previous works. The approach used here combines the Guo–Krasnoselskiĭ fixed-point theorem and the sub-supersolutions method with some estimates on related nonlinear problems.
Risk factors of tuberculosis in children with adult household tuberculosis contact
Authors: Setyoningrum Retno Asih , Maharani Rizky Arisanti , Hapsari Rika , Chafid Arda Pratama Putra
Published: September 2024

Background Since children are more likely than adults to become infected with Mycobacterium tuberculosis or suffer from tuberculosis (TB), it is important to identify the risk factors of TB in children with adult household TB contacts.
Objective To identify the risk factors of TB in children with adult household TB contacts. Methods This cross-sectional study was conducted at the Pediatric Respirology Inpatient Ward and Outpatient Clinic at Dr. Soetomo Hospital, Surabaya, Indonesia, using medical records of hospitalized patients from 2010 to 2018. Patients were children below 18 years of age who had a history of adult TB household contact(s). We analyzed age at TB diagnosis, nutritional status, BCG vaccination status, and HIV status as possible risk factors of TB.
Results A total of 367 children with adult household TB contacts were included in our study. Age of <5 years (OR 8.38; 95%CI 3.78 to 18.21; P<0.001), severe malnutrition (OR 8.88; 95%CI 1.19 to 66.27, P<0.05), absence of BCG scar (OR 2.96; 95%CI 1.32 to 6.62, P<0.05), and positive HIV status (OR 6.72; 95%CI 1.72-38.49, P<0.05) were risk factors for contracting active TB.
Conclusion Age of <5 years, severe malnutrition, absence of BCG scar, and positive HIV status are significant risk factors for active TB in children with adult household TB contacts.
Prevalence and risk factors of depression in juvenile systemic lupus erythematosus
Authors: Puspitanza Ika Dian , Alia Myrna , Kesuma Yudianita , Rismarini Rismarini , Novery Edy , Bahar Erial
Published: September 2024

Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems, including the central nervous system. Depression is one of the neuropsychiatric manifestations of juvenile SLE .
Objective To estimate the prevalence of depressive disorders in juvenile SLE and identify its potential risk factors.
Methods This cross-sectional study was conducted in juvenile SLE patients at Dr. Mohammad Hoesin General Hospital, Palembang. Sociodemographic data and medications were recorded. Disease activity of SLE was assessed using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Physical activity was measured using the Physical Activity Questionnaire for Children (PAQ-C) and the Physical Activity Questionnaire for Adolescents (PAQ-A). All subjects were screened for depression using the Childhood Depression Inventory (CDI) questionnaire. Multiple linear regression analyses were used to determine risk factors for depressive disorders.
Results We included 72 patients, of whom 67 (93.1%) were female. Mean age of the patients was 12 years 4 months (SD 2 years 6 months); most (67; 93.1%) were 10-18 years of age. Depression was found in 24 patients (33.3%). SLEDAI scores of ?3 (flare) were found in 54 patients (75%) and low physical activity was found in 62 (86.1%) patients. The prevalence of depression based on the Children's Depression Inventory was 33.3%. A SLEDAI score of ?3 and low physical activity were significantly associated with depression (P=0.009 and P=0.025, respectively). On multiple linear regression analysis, only SLEDAI score of ?3 remained significantly associated with depression (P= 0.017; OR 12.6; 95%CI 1.6–101.7). Gender, age, family economic status, father's education, mother's education, family history of depression, and duration of illness were not associated with depression.
Conclusion A SLEDAI score indicating flare (?3) and low physical activity are significantly associated with an increased risk of depression. A SLEDAI score is an independent risk factor for depression when all other significant risk factors are considered.
Clot waveform analysis to differentiate mild, moderate, and severe hemophilia A
Authors: Timan Ina Susianti , Chozie Novie Amelia , Santoso Novianti
Published: September 2024

Background Clot waveform analysis can be used to evaluate clot formation profiles. This waveform can be obtained from activated partial thromboplastin time (APTT) assays without additional reagents and shows different patterns in hemophilia patients with coagulation factor VIII (F VIII) deficiency or abnormality.
Objective To determine the clot wave pattern and its process in clot formation phases (pre-coagulation, coagulation, and post-coagulation) in normal and hemophilia A subjects, analyze for possible correlations between clot wave parameters and F VIII activity, and obtain the pattern of coagulation curves in hemophilia subjects as a step to assess clot waveform analysis as a possible screening tool for hemophilia.
Methods In this cross-sectional study, we performed clot wave analysis in 145 adult and pediatric subjects with hemophilia to obtain the clot wave pattern in this condition. Clot wave analysis was also done in 160 subjects with normal hemostasis to obtain reference clot wave parameters.
Results In this study, the starting point of coagulation phase in normal subjects was between 30-40 seconds, with a shorter pre-coagulation phase and steeper slope. Hemophilia patients had a longer pre-coagulation phase and flatter slope, especially in severe hemophilia A patients, who had longer and more variable coagulation starting points (P<0.001). The absolute values of maximum coagulation velocity (Min1), maximum coagulation acceleration (Min2), and maximum coagulation deceleration (Max2) of hemophilia A patients were also lower than those of normal hemostasis patients, with lower absolute value seen in severe than in mild-moderate hemophilia A patients. A moderate correlation was found between Min1, Min2, and Max2 with F VIII activity (P<0.001).
Conclusion Clot wave analysis may be considered as a method for screening hemophilia patients to distinguish mild-moderate and severe hemophilia A patients in health facilities that lack the ability to perform F VIII assays.
H1N1pdm09 infection in children: A case report of reemerging disease in COVID-19 pandemic
Authors: Puspaningtyas Niken Wahyu , Nagrani Dimple Gobind , Karyanti Mulya Rahma , Fauzie Rifan , Imanadhia Ashfahani , Sarita Raisa Cecilia , Putra Reynaldo Rahima
Published: September 2024

An outbreak of H1N1 infection was first declared by the World Health Organization in 2009 and confirmed in the post-pandemic phase in 2010. Amid the COVID-19 pandemic, we found a confirmed case of H1N1pdm09 in Bunda Women and Children Hospital Jakarta. A 13-year-old boy was referred to our hospital after four days of hospitalization due to worsening tachypnea following a productive cough and fever. The patient had severe dyspnea with inspiratory effort and oxygen desaturation to 80%, therefore admitted to our pediatric intensive care unit. On physical examination, the patient had increased work of breathing, looked irritable, had a respiratory rate of about 40x/minute with non-rebreathing mask support, and crackles were heard in both lungs. Chest x-ray showed right bronchopneumonia. There was a history of a generalized seizure for less than 1 minute, which stopped spontaneously in previous hospital care. The patient was diagnosed with mucopolysaccharidosis at age six years old and has never received enzyme replacement therapy. Laboratory results revealed thrombocytopenia, leukopenia, neutrophilia, monocytosis, high c-reactive protein and procalcitonin, and elevated liver enzymes. The investigation of etiology was performed using the respiratory panel test and showed a positive real-time polymerase chain reaction for H1N1pdm09 and Influenza A. The patient was given oxygen therapy with a high-flow nasal cannula with an oxygen fraction of 40% and a flow of 20 liters per minute, fluid maintenance while fasting, antibiotics, inhaled beta-2 agonists, and a neuraminidase inhibitor (oseltamivir). The patient's clinical and laboratory markers improved on the third day of treatment, and he was discharged two days later.
Analysis of GFRP-reinforced beams in enhanced SCC
Authors: Chidambaram Prithiviraj , Jagadeesan Saravanan
Published: September 2024

This study investigated the flexural behaviour of glass fibre-reinforced polymer (GFRP)-reinforced beams with two different ratios (0.68 % and 1.03 %) using traditional Self-Compacting Concrete (SCC) and SCC with 30 % Ultrafine Slag (UFS). The study analysed crack patterns, failure modes, load-deflection responses, strains in the concrete and reinforcement, and the influence of the reinforcement ratio and SCC compressive strength. The results indicated that under-reinforcement led to the rupture of the GFRP, balanced reinforcement resulted in bar and concrete failures, and over-reinforced beams mainly experienced compression zone concrete crushing. This study compared the ACI Flexural Design Guidelines (2015) with the experimental data.
Prevalence and Antifungal Susceptibility of Candida species from patients attending Rivers State University Teaching Hospital, Nigeria
Authors: D. N Girah , N. P Akani , O Aleruchi
Published: September 2024

The development of medical therapy and patients profile has led to a rise in the incidence of nosocomial fungal infection. The frequency of candidiasis has surged worldwide, and the prevalent of healthcare diseases are now Candida species. Candida species causes a range of human infections known as Candidiasis. The non-albicans Candida (NAC) species have recently superseded Candida albicans as significant opportunistic pathogens. The study was conducted to determine the prevalence and antifungal susceptibility of Candida species isolated from various Clinical samples in Rivers State University Teaching Hospital, Port Harcourt, Nigeria. A total of 206 clinical specimens from male and female patients of all ages were sampled in the Department of Microbiology, Rivers State University Teaching Hospital, Port Harcourt, to investigate suspected Candida infections. The isolation and identification of Candida species was done by culture on SDA, Gram stain, sugar fermentation and phylogenetic profiling. Antifungal susceptibility pattern was done by Disc Diffusion method using Fluconazole, Ketoconazole, Miconazole, Nystatin and Itraconazole. The results showed that out of 206 specimens, 44 isolates (21.4%) were identified, with the majority (56.82%) from high vaginal swabs (HVS), followed by urine (31.82%) and oral swabs (11.36%). The age of patients ranged from four months to 73 years giving a Mean Age 1.86+ 0.344, with females (85.4%) outnumbering males (13.6%). Prevalence of Candida spp revealed Candida albicans (50%), Candida krusei (18.2%), Candida parapsilosis (11.4%), Candida glabrata and Candida tropicalis (9.1%) respectively and Candida pelliculosa (2.2%), with C. albicans being the most prevalent. The antifungal susceptibility testing among the azoles showed that Fluconazole (79.5%) and Ketoconazole (77.3%) were most sensitive agents against isolates from HVS, urine and oral swabs respectively and Itraconazole (34.1%) was most resistant especially to those from oral swabs. This study highlights the increasing prevalence of NAC species over Candida albicans and the growing resistance of Candida isolates to commonly used antifungal drugs. Diagnosis of these species of Candida and sensitivity to antifungal agents are critical components to treatment, particularly for patients with severe underlying illnesses who are hospitalized.
Model of organisational competencies and capabilities for effective innovation management
Authors: Carvalho Proença Joaquim Jose
Published: September 2024

Introduction / objective: Evaluating the effectiveness of innovation programmes, particularly in terms of their long-term impact on companies, is inherently complex. This study aims to develop a comprehensive measurement model that effectively captures the long-term innovation and sustainability outcomes of such programmes. By focusing on a broad spectrum of organisational competencies and capabilities, this model seeks to provide a holistic assessment of innovation effectiveness within participating companies. Methodology: To construct the measurement model, a thorough literature review was conducted. Relevant articles were analysed to identify patterns and themes, leading to the classification of essential dimensions, processes, tools, and indicators of organisational competencies and capabilities that are critical for fostering innovation. Results: The study proposes a reference model of organisational competencies, named the 8Cs, to evaluate companies’ innovation performance and potential. This model includes 27 indicators across key dimensions: Cognisance/Knowledge Management, Critical Thinking, Creativity, Innovation Capabilities, Collaboration, Innovative Culture, Change Management and Communication. Conclusions: The 8C model significantly enhances innovation management by providing a comprehensive assessment framework for companies’ innovation practices and their long-term impact. It highlights specific competencies and capabilities essential for sustained innovation and competitiveness, enabling companies to identify focus areas, assess innovation sustainability, and allocate resources effectively.
Análise e descrição paramétrica de microestrutura de instrumentos lexicográficos impressos do sinal do léxico ‘futebol’
Authors: Marcelino Gilmar Garcia , Garcia Renata Rodrigues de Oliveira , Carvalho Andréa dos Guimarães de
Published: September 2024

Este artigo analisa a representação do sinal FUTEBOL no léxico comum da Língua Brasileira de Sinais (Libras) em dois dicionários lexicográficos distintos: um da Tipografia Universal de E. & H. Laemmert (Gama, 1875) e outro da Editora da Universidade de São Paulo (Capovilla et al., 2017). O objetivo é examinar as microestruturas dos verbetes desses dicionários para entender como são descritos e utilizados. A metodologia se baseia nos estudos de Lexicologia e Lexicografia de Faulstich (2010, 2011, 2016) e Fromm (2003), que explicam os elementos que formam os verbetes em Língua Portuguesa (LP) e Libras. Os resultados revelaram que, embora os dicionários sejam ferramentas úteis, há uma lacuna na descrição de conceitos e significados dos sinais. Os verbetes nos dicionários analisados não oferecem explicações complementares que ajudariam na compreensão do uso dos sinais na Libras. Essa falta de detalhes pode levar a uma insatisfação entre linguistas e praticantes do esporte quanto à representação tridimensional dos sinais e seu uso em contextos diversos. O sinal FUTEBOL no léxico comum da Libras é identificado como uma variação linguística importante no Brasil. A comparação entre os dicionários antigos e mais recentes mostra uma ampliação dos conceitos linguísticos, mas também destaca a necessidade de melhorias na forma como os sinais são apresentados e descritos, a fim de refletir melhor seu uso real e contextos variados na Libras.
Kouřimská partikulární škola v období mezi prvním a druhým stavovským povstáním
Authors: Šťastný Daniel
Published: September 2024

This article describes the functioning of a Latin grammar school (so-called ‘particular’ school) in Kouřim and its links to the Charles University of Prague in the period of 1547–1622. The author investigates the economic situation of the school, its staff, the students, and their relations to the townspeople. Explored is also teacher and student mobility, the school’s relationship with the university, and the school’s alumni. New findings have been confronted with previous research.
Wojciech Świeboda, Universitas contra haeresim. Działalność antyheretycka Stanisława ze Skarbimierza jako przedstawiciela Uniwersytetu Krakowskiego, Kraków 2021
Authors: Zilynská Blanka
Published: September 2024

Book review on Wojciech Świeboda, Universitas contra haeresim. Działalność antyheretycka Stanisława ze Skarbimierza jako przedstawiciela Uniwersytetu Krakowskiego Towarzystwo Naukowe Societas Vistulana, Kraków 2021, 318 s., ISBN 978-83-65548-86-3, (Historia et Monumenta Universitatis Jagellonicae VII, red. Krzysztof Ożóg)
Milan Řípa, Ronald Richter: Termojaderná fúze první na světě: Sokolov 1936, Sokolov 2021
Authors: Boukal Jan
Published: September 2024

Book review on Milan Řípa, Ronald Richter: Termojaderná fúze první na světě: Sokolov 1936, Muzeum Sokolov, příspěvková organizace Karlovarského kraje, Sokolov 2021, 67 stran, ISBN 978-80-86630-47-2
Daniela Brádlerová, Milada Paulová, první česká profesorka: mezi soudobými dějinami a byzantologií, Praha 2021
Authors: Veverková Andrea
Published: September 2024

Book review on Daniela Brádlerová, Milada Paulová, první česká profesorka: mezi soudobými dějinami a byzantologií, Masarykův ústav a Archiv AV ČR, Praha 2021, 377 s., ilustrace, portréty, faksimile, ISBN 978-80-88304-73-9
Vojtech Ozorovský (ed.), Dejiny Lekárskej fakulty Univerzity Komenského v Bratislave, II, Bratislava 2021
Authors: Svobodný Petr
Published: September 2024

Book review on Vojtech Ozorovský (ed.), Dejiny Lekárskej fakulty Univerzity Komenského v Bratislave, II. časť, Univerzita Komenského v Bratislave, Bratislava 2021, 456 s., ISBN 978-80-223-5295-6
The Restoration of Hope and Dignity in the Context of the Sexual Abuse Crisis in the Church
Authors: De Mey Peter
Published: September 2024

This article looks at the sexual abuse crises that have hit churches around the world, especially the Roman Catholic Church, and asks if it is possible to talk of hope in such circumstances. It asks whether theology has a role to play or a responsibility for the crisis, and what sort of church is called for in the light of it. The article ends by suggesting possible places of hope that do not seek to impose on the survivors.
Synergistic effects of nitrogen and naphthalene acetic acid on growth, yield and nutritional content of Stevia (Stevia rebaudiana Bertoni)
Authors: Islam Md. Shariful , Mahmud Md. Riaz , Hossain Md. Sohag , Amin Mehedi , Khan Md. Sirajul Islam , Islam Mohammed Ariful
Published: September 2024

Stevia farming in Bangladesh is increasingly significant due to limitations in cane sugar production and the rise in diabetic cases. This study examined how nitrogen and naphthalene acetic acid (NAA) affect Stevia development, production and nutritional content on the experimental farm of the regional station of the Bangladesh Sugarcrop Research Institute, Thakurgaon. Various nitrogen treatments (N1: untreated, N2: 105 kg ha-1, N3: 140 kg ha-1, N4: 175 kg ha-1, N5: 210 kg ha-1) and NAA applications (H1: untreated, H2: 50 mg/L, H3: 100 mg/L, H4: 150 mg/L) were administered employing a randomized complete block design (RCBD). Results showed that N3 and H3 treatments produced the highest yield, averaging 10.06 % more than other doses. Stevia leaf nutrients like nitrogen (3.47 %), potassium (0.19 %) and magnesium (0.15 %) were also influenced by N3H3 treatment. The study suggests that for Stevia cultivation in northern Bangladesh, an optimal nitrogen application rate of 140 kg ha-1 and an NAA concentration of 100 mg/L are recommended.
Europas Nationalbibliotheken – das Gedächtnis des Kontinents
Authors: Gömpel Renate
Published: September 2024

Seit 1987 setzt sich die Conference of European National Librarians (CENL) für die Belange der europäischen Nationalbibliotheken ein und unterstreicht damit ihre besondere Rolle bei der Bewahrung des kulturellen Erbes des Kontinents und dessen Zugänglichkeit für alle.

https://www.cenl.org/about-cenl/.

In diesem Beitrag geht es um die Anfangsjahre, speziell um die Wendezeit in Mittel- und Osteuropa, den Ost-West-Dialog und die daraus entstandene Entwicklung der Zusammenarbeit der europäischen Nationalbibliotheken.
Atypical cells in urine sediment: a novel biomarker for early detection of bladder cancer
Authors: Wang Yinling , Zheng Jun , Liu Yang , Li Dongqi , Jin Danning , Luan Hong
Published: September 2024

Objectives

Atypical cells (Atyp.C), as a new parameter determined by an automated urine analyzer, can be suspected of being malignant tumor cells. We evaluated the extent to which the Atyp.C can predict the existence of malignant tumor cells.

Methods

A total of 3,315 patients (1,751 in the training cohort and 1,564 in the testing cohort) were recruited and divided into five groups, namely, primary bladder cancer (BCa), recurrent BCa, post-treatment monitoring of BCa, other urological tumors, and controls. Urine Atyp. C, bacteria, white blood cell, and red blood cell were measured by a Sysmex UF-5000 analyzer. We compared the Atyp.C values across the different groups, sexes, and tumor stages. The diagnostic performance of Atyp.C alone and in combination with other parameters for detecting BCa was evaluated using receiver operating characteristic (ROC) curve analysis.

Results

The Atyp.C value of the primary BCa group was significantly higher than that in the other groups, except recurrent BCa group. The Atyp.C value was closely related to tumor staging. Atyp.C combined with bacteria had the highest diagnostic performance for primary BCa [training cohort AUC: 0.781 (95 % CI: 0.761–0.801); testing cohort AUC: 0.826 (95 % CI: 0.806–0.845)]. The AUC value of diagnosed recurrent BCa by Atyp.C plus bacteria for the training cohort was 0.784 (95 % CI: 0.762–0.804).

Conclusions

Atyp.C was high in primary BCa patients and the combination of bacteria and Atyp.C showed high predictive value for primary BCa, suggesting that Atyp.C may be a useful objective indicator for the early detection of BCa.
Cleaner Production: Analysis of the Role and Path of Green Finance in Controlling Agricultural Nonpoint Source Pollution
Authors: Shen Yang , Zhang Xiuwu
Published: September 2024

This study evaluates the impact of green finance (GF) on agricultural nonpoint source pollution (ANPSP) control and emission reduction in 30 Chinese provinces from 2005 to 2021. Utilizing the entropy value method and the unit survey inventory method, the research measures the levels of GF development and ANPSP. It employs a mediation effect model to empirically assess the pollution control efficacy of GF and to elucidate the mechanisms underlying its influence. The findings indicate that GF development significantly curtails ANPSP emissions. It achieves this through government environmental regulation (ER) and land transfer mechanisms. Heterogeneity test results show that GF has a stronger impact on ANPSP in regions with lower economic development level and GF reform policies. Therefore, the study suggests strengthening the GF infrastructure in rural areas, aligning GF policies with ER, promoting large-scale land operations, and implementing tailored strategies for regions with different levels of economic development and GF reform policies.
25-Hydroxyvitamin-D levels in Sjögren’s syndrome: is it the right time to dismiss the case or not?
Authors: Karabulut Gonca , Yilmaz Zevcet , Yildirim Simsir Ilgin , Barutcuoglu Burcu , Tanigor Goksel
Published: September 2024

Objectives

This study aimed to investigate whether patients with primary Sjögren syndrome (SjS) have different levels of 25 OH-D3 (vitamin D) when compared to healthy populations and whether differences in 25 OH-D3 correlated with disease activity or markers.

Methods

Eighty-eight female patients with SjS and 3,338 age-matched healthy female controls were included in this study. 25 OH-D3 levels were compared with healthy controls. Then the patients were stratified according to their 25 OH-D3 levels, either insufficient/deficient or normal (<50 nmol/L or ≥50 nmol/L). The disease activity was evaluated using The EULAR SjS disease activity index (ESSDAI) and its components. Correlation analyses were also performed for a possible correlation with disease characteristics and markers of activity.

Results

No differences in 25 OH-D3 levels were found between SjS and healthy populations (p>0.05). No correlations were found between patient characteristics or laboratory values (p>0.05).

Conclusions

This study did not find a link between disease characteristics and disease activity and 25 OH-D3 levels. Prospective studies with more patients should be conducted to reach a conclusion.
Modeling Approach of Cloud 4D Printing Service Composition Optimization Based on Non-Dominated Sorting Genetic Algorithm III
Authors: Liu Jiajia , Zainudin Edi Syams , As'arry Azizan , Ismail Mohd Idris Shah
Published: September 2024

The manufacturing industry is currently experiencing a paradigm shift from traditional centralized systems to distributed, personalized, and cloud-based intelligent manufacturing ecosystems. The advent of 4-dimensional (4D) printing technology introduces dynamic characteristics to manufacturing design and functionality, necessitating the effective management of these emergent 4D printing services. This study aims to bridge the gap between the static nature of existing cloud manufacturing services and the dynamic requirements imposed by 4D printing technology. We propose a comprehensive multiobjective optimization model for cloud-based 4D printing service portfolios, incorporating the intricate complexities of 4D printing services and assessing the efficacy of the Non-Dominated Sorting Genetic Algorithm III (NSGA III) in optimizing these service portfolios to meet dynamic demands. In this research, the NSGA III algorithm is employed to develop a multiobjective optimization framework for 4D printing service portfolios, addressing critical issues such as service cost, time, quality, adaptability, and overall service optimization amidst fluctuating demand and service availability. The findings indicate that the NSGA III algorithm demonstrates superior performance in terms of generational distance (GD) and inverted generational distance (IGD), particularly excelling in convergence and diversity for high-dimensional optimization problems when compared to the comparison algorithms. The study concludes that the NSGA III algorithm exhibits significant potential in optimizing the orchestration of cloud-based 4D printing service portfolios, underscoring its effectiveness in managing the complexities associated with these services. This research provides valuable insights for the advancement of intelligent cloud-based 4D printing systems, paving the way for future developments in this field.
A Simplified Failure Assessment to Identify Crack Growth Behavior in the Gas Pipeline by Post-Hydrostatic Pressure
Authors: Assidiq Fuad Mahfud , Juswan  , Paroka Daeng , Rachman Taufiqur , Japri Rahmahdani , Wahyudi Slamet
Published: September 2024

Hydrostatic pressure tests on pipelines have been found to be an inadequate means of critical integrity management due to the frequency of false negatives, which result from the inability of these tests to detect crack growth. It can be argued that focusing on pipe leakage does not guarantee future operability. A study presents a failure assessment methodology based on the failure assessment diagram (FAD), which aims to predict crack growth during hydrotesting. The calibrated pipe spool is validated by the application of data from hydrostatic tests and analytical techniques to ascertain the potential growth in circumferential surface cracks. A variety of factors, including pressure, material grades, flaw dimensions, and elliptical flaw angles, were examined in an effort to assess cracks. The results demonstrate that there is no pipeline leakage and minimal trapped air. Despite its location within the plastic zone, with a normalized pressure index of ≤1, the pipeline is deemed to be within acceptable limits according to the criteria established by the FAD. The assessment point was found to be predominantly influenced by the toughness ratio of the material grade. The crack propagated in the opposite direction with a maximum length a/c= 0.125 and a crack depth a/t= 0.2, which limited the toughness ratio. The load ratio indicates uniformity in elliptical angle flaw results. In this simplified failure assessment, the parameter describing the flaw size, which exhibits a strong correlation with the toughness ratio, plays a pivotal role. Further research and recommendations are also proposed.
Revolutionizing Wing-in-Ground Effect: Investigating Structural Rigidity
Authors: Ibrahim Rasidi , Saroni Iffat Syahmi , Ahmad Aishah , Mohid Zazuli , Hong Chong Bin , Abidin Razali
Published: September 2024

The Wing-in-ground (WIG) effect aircraft utilize the ground effect to maintain flight above water or another surface while minimizing continuous contact with the ground. The propulsion of this aircraft primarily relies on the aerodynamic lift generated by specially designed wings, hulls, or other components that harness the ground effect phenomenon. The problem statement that occurs once conventional boats fail to successfully carry out the mission of intercepting intruders trespassing on national waterways. Due to inherent constraints in watercraft technical standards, existing watercraft technology lacks the power to pursue intruders to their full extent. To further improve the WIG craft operation, we propose enhancing its performance by using materials with better mechanical qualities and optimizing the construction to lower its overall size. These enhancements aim to bolster the WIG craft's capabilities and enable more efficient and effective interception of intruders in water environments. This research aims to investigate structural material qualities suited for WIG effect application and structural rigidity characteristics, with a particular focus on the joining model. In order to accomplish these objectives, the study utilizes Solidworks simulation to replicate the WIG craft model. The static simulation involves testing four different parameters: Models A, B, C, and D. The key focus during the model simulation is varying the types of connections used. The simulation data is then examined to estimate the strength of the material structure. The material applied to the WIG craft structure is S-glass fiber and 6061 aluminum alloy. Model D produced acceptable values for the least maximum stress, strain, and resultant displacement, among other models. The maximum stress value of Model D is 1,601 MPa, which does not exceed the tensile strength of the material. For the rigidity analysis in operating conditions, the Solidworks flow simulation is conducted. The manipulated variable for flow simulation is the velocity of airflow. The velocities conducted are 60 km/h, 90 km/h, 120 km/h, 15 km/h and 180 km/h. The flow simulation shows the maximum total pressure exerted on the structure, where the highest velocity produced is 103433 Pa. From both static and airflow simulation, it was concluded that the WIG craft model has good rigidity in terms of withstanding the external load and airflow pressure during the cruising conditions proposed.
Robust H∞ Control Design for Improving Handling and Ride Comfort in Semi-Active Suspension Systems
Authors: Yeneneh Kumlachew , Mamo Tatek , Walle Menelik , Birhanu Biru
Published: September 2024

This study investigates the application of robust H∞ control design for semiactive suspension systems. The goal is to achieve a balance between ride comfort and handling. A quarter-car model is used to simulate the system's dynamics. The findings demonstrate that the robust H∞ control approach with μ-synthesis offers significant advantages compared to traditional passive control and nominal H∞ control methods. When compared to the passive system, the robust H∞ controller with μ-synthesis results in a 50% reduction in body displacement (from 0.04 meters to 0.02 meters) during a simulated road bump. It also achieves a 25% reduction in peak body acceleration (from 4 m/s² to 3 m/s²) and a 37.5% reduction in suspension deflection (from 0.04 meters to 0.025 meters). These improvements translate to a smoother ride with less body movement and improved handling due to better tire contact with the road. The μ-synthesis method specifically addresses uncertainties like passenger weight and road conditions. This leads to more consistent performance in real-world driving scenarios. Overall, this study highlights the effectiveness of robust H∞ control design in achieving a well-balanced suspension system that enhances both ride comfort and handling.
Glucocorticoid excess alters metabolic rate and substrate utilisation via 11β-HSD1
Authors: Heaselgrave Samuel R , Heising Silke , Morgan Stuart A , Carthwright David M , Sagmeister Michael , Hardy Rowan S , Doig Craig L , Morton Nicholas , Tsintzas Kostas , Lavery Gareth G
Published: September 2024

Systemic glucocorticoid excess causes several adverse metabolic conditions, most notably Cushing’s syndrome. These effects are amplified by the intracellular enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). Here, we determined the less well-characterised effects of glucocorticoid excess, and the contribution of 11β-HSD1 amplification on metabolic rate in mice. Male and female C57BL/6J (wild type, WT) and 11β-HSD1 knockout (11β-HSD1 KO) mice were treated with high-dose corticosterone or a vehicle control for 3 weeks. Indirect calorimetry was conducted during the final week of treatment, with or without fasting, to determine the impact on metabolic rate. We found that corticosterone treatment elevated metabolic rate and promoted carbohydrate utilisation primarily in female WT mice, with effects more pronounced during the light phase. Corticosterone treatment also resulted in greater fat accumulation in female WT mice. Corticosterone induced hyperphagia was identified as a likely causal factor altering the respiratory exchange ratio (RER) but not energy expenditure (EE). Male and female 11β-HSD1 KO mice were protected against these effects. We identify novel metabolic consequences of sustained glucocorticoid excess, identify a key mechanism of hyperphagia, and demonstrate that 11β-HSD1 is required to manifest the full metabolic derangement.
La biblioteca personal de Abelardo Jaén Machuca (1894-1972): huellas literarias en la vida de un compositor
Authors: Fresneda Roca África , López Núñez Norberto
Published: September 2024

The figure of the musician and composer Abelardo Jaén Machuca (1894-1972) left his musical mark on Elche (Alicante, Spain) in the first half of the 20th century. His legacy includes a private library that houses a collection of more than 150 books. The aim of this research is to show the interrelationship between the composer and his books, both personally and professionally. To this end, methodologies analogue to similar studies of private libraries are used, drawing up an inventory of books and their classification by subject, and determining the evidence found by using qualitative methods. The results show a special interest in contemporary music, sometimes present in his mostly traditionalist compositions, and an intimate relationship between the different subjects and the composer's biographical stages, which helps in the reconstruction of his musical career.
ABSORPTION SPECTRUM OF H217O BETWEEN 7900 AND 9500 CM-
Authors: СЕРДЮКОВ В.И. , СИНИЦА Л.Н. , МИХАЙЛЕНКО С.Н.
Published: September 2024

Спектр поглощения водяного пара с высоким содержанием 17O (более 80%) зарегистрирован на Фурье-спектрометре Bruker IFS 125M в диапазоне 7900-9500 см-1 при комнатной температуре. В зарегистрированном спектре найдено около 6300 линий с минимальной интенсивностью 5,0 × 10-27 см/молек. 4835 линий спектра отнесены к 5185 переходам пяти изотопологов молекулы воды (H216O, H217O, H218O, HD16O и HD17O). Линии H217O отнесены к 14 колебательным полосам, из них большая часть к ν2 + 2ν3, 3ν2 + ν3, ν1 + ν2 + ν3, ν1 + 3ν2 и 2ν1 + ν2. Впервые идентифицированы линии горячих полос ν1 + 2ν2 + ν3 - ν2, 2ν1 + ν3 - ν2 и 2ν1 + 2ν2 - ν2. Идентификация позволила определить более 153 новых колебательно-вращательных уровней энергии девяти колебательных состояний молекулы H217O и 22 уровня энергии двух состояний молекулы HD17O. Проведены сравнения полученных данных с результатами предыдущих исследований, спектроскопической базой HITRAN2020 и списком W2020.

Absorption spectrum of water vapor highly enriched with 17O (more than 80%) was recorded using a Bruker IFS 125M Fourier spectrometer in the 7900-9500 cm-1 range at room temperature. The spectrum was recorded at a pressure of about 24 mbar with a spectral resolution of 0.02 cm-1. About 6300 lines with a minimal intensity value of 5.0 × 10-27 cm/molecule are found in the recorded spectrum. 4835 recorded lines are assigned to 5185 transitions of five water isotopologues (H216O, H217O, H218O, HD16O, and HD17O). H217O lines are assigned to 14 vibration bands. Most of them are the lines of the ν2 + 2ν3, 3ν2 + ν3, ν1 + ν2 + ν3, ν1 + 3ν2, and 2ν1 + ν2 bands. The lines of the ν1 + 2ν2 + ν3 - ν2, 2ν1 + ν3 - ν2, and 2ν1 + 2ν2 - ν2 hot bands are assigned for the first time. The assigned lines allow us to determine 153 new vibration-rotation energies of nine vibrational states of the H217O molecule and 22 energies of two states of the HD17O molecule. The data obtained are compared with the results of previous studies, the HITRAN2020 spectroscopic database, and W2020 list.
EFFECTS OF WIND AND TOPOGRAPHY ON THE DYNAMICS OF THE AUTUMNAL THERMAL BAR IN LAKE BAIKAL
Authors: ЦЫДЕНОВ Б.О.
Published: September 2024

На примере оз. Байкал методами численного моделирования исследуется совместное влияние ветра и морфологических характеристик водоема на его термическое состояние и особенность развития осеннего термобара. Установлено, что при метеорологических условиях с 1 по 30 ноября 2015 г. поведение термобара в начальной стадии его развития на разрезе р. Болдакова - прол. Малое Море более чувствительно к ветровому воздействию, чем на разрезе прот. Средняя (дельта р. Селенги) - р. Бугульдейка. Однако распространение фронта термобара и охлаждение вод в Селенгинском мелководье происходит более быстрыми темпами.

The combined effect of wind and lake topographic characteristics on the temperature distribution and autumnal thermal bar evolution on an example of Lake Baikal was studied by numerical modeling. It was determined that under meteorological conditions in November 1-30, 2015, the thermal bar behavior at an initial stage of its development on the Boldakov River - Maloye More Strait cross-section was more sensitive to the wind action than that on the Srednyaya arm (Selenga River Delta) - the Buguldeika River cross-section. However, faster water cooling and thermal front propagation take place in the Selenga shallow water basin.
SEASONAL AND DAILY VARIATIONS IN THE OPTICAL RADIATION EXTINCTION COEFFICIENT DUE TO MIDGES IN THE SURFACE AIR IN WESTERN SIBERIA IN SUMMER-AUTUMN 2018
Authors: ЩЕЛКАНОВ Н.Н.
Published: September 2024

Представлены сезонные и суточные вариации коэффициента ослабления оптического излучения за счет гнуса в июне, июле, августе и сентябре 2018 г. в Западной Сибири. Средние значения коэффициентов ослабления излучения гнусом в видимой и инфракрасной областях спектра составили: ~ 0,06 км-1 в июне, ~ 0,05 км-1 в июле, ~ 0,04 км-1 в августе и 0,02 км-1 в сентябре. Суточный ход в эти месяцы имеет два максимума: первый приходится на 09:00; второй более выражен и наблюдается в 17:00. Минимальные значения коэффициентов наблюдаются в ночные часы (01:00-05:00) и в 12:00. Некоторые дни сентября характеризуются дополнительным типом суточного хода с одним максимумом в дневные часы и минимумом в темное время суток.

The seasonal and daily variations in the radiation extinction coefficient due to midges (RECM) in Western Siberia are calculated for June, July, August, and September 2018. The average RECM values in the visible and infrared spectral regions were ~ 0.06 km-1 in June, ~ 0.05 km-1 in July, ~ 0.04 km-1 in August, and ~ 0.02 km-1 in September. There are two maxima in the daily variations in June, July, August, and September. The first maximum falls at 9 a.m. The second maximum is more pronounced and is observed at 17 p.m. The RECM is minimal in nighttime and at noon. In addition, a different daily behavior is characteristic for certain days of September, with a maximum in daytime and a minimum in nighttime.