bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictors of subjective wellbeing at work for regular employees in Japan
Authors: Magnier-Watanabe Remy , Benton Caroline , Orsini Philippe , Uchida Toru
Published: March 2023

Japan has been experiencing a long decline in its workforce. Companies in Japan are eager to retain their existing employees and diversify their recruitment. Employees with long-term and open-ended employment are also switching companies at a greater rate. Consequently, Japanese firms have started paying attention to employee subjective wellbeing, now recognized as a source of higher job performance. This study empirically explores the predictors of subjective wellbeing at work for Japanese regular employees beyond those already identified in Europe and U.S.-centric research. We applied a two-stage design, consisting of interviews and a questionnaire survey to identify those factors that promote subjective wellbeing in Japanese corporations where long-time employment and group cohesiveness and achievement are valued over individual achievement. We identified eight factors affecting subjective wellbeing at work for Japanese regular employees: meaningful work, relationships, culture, workspace, evaluation, time off, financial benefits, and diversity at work. Consequent regression analyses highlighted the discriminant importance of work relationships, evaluation, diversity, workspace, and meaningful work. Eudaimonic and hedonic happiness were found to be caused by different factors. As expected, meaningful work led to eudaimonic satisfaction of life at work in Japan. In contrast hedonic happiness was affected by factors external to work itself, such as work relationships, work evaluation and diversity. Interestingly, diversity at work was found to have an ambivalent effect as it was related to both positive and negative affects at work. These findings will help Japanese companies create a work environment that can maximize regular employees’ wellbeing, job performance, and retention.
MAQĀṢID AL-SYARĪ’AH DALAM TINJAUAN PEMIKIRAN IBNU ‘ĀSYŪR
Authors: Muchasan Ali , Syarif M. , Rohmawan Dhuhaa
Published: March 2023

Maqāṣid Al-Syarī'ah from the perspective of Ibnu 'Āsyūr, a contemporary scholar who has contributed greatly to developing maqasidus sharia, not only from the point of view of how Islamic law becomes a means for individuals to get closer to God, but also how humans actually function as individual beings , social beings and Godly beings. Understanding and developing Maqasidus sharia knowledge becomes tenting for us to be able to feel the spirit of tasyri' so that our faith will increase. Maqasid al Sharia can be in the form of maqasid al'ammah sharia, which covers all aspects of sharia and Maqāṣid Al-Syarī'ah al khasah which is devoted to one of the chapters of sharia that has chapters, such as maqasid al sharia in economics, family law and others , or Maqāṣid Al-Syarī'ah al juz'iyyah which includes every syara' law such as the obligation to pray, forbidden adultery, and so on. In this paper, the discussion will be focused on the maqashid sharia theory according to Ibn 'Āsyūr. With the hope of knowing the characteristics and uniqueness of the theory. This research is a research that uses a qualitative descriptive approach using the literature study method, namely by searching for and studying literature related to the problem that is the object of this research study. Ibn 'Āsyur on maqashid al syar'iyyah.
Managing students' mental health: The use of NGT and FDM to generate a concrete solution
Authors: Mustapha Ramlan , Paris Tengku Nazatul Shima Tengku , Mahmud Maziah , Musa Mohamad Sahizam , Zaini Azniza Ahmad , Zakaria Jazimin
Published: March 2023

The impact of steps to minimize transmission of COVID-19 has increased awareness of the importance of addressing the worsening mental health of students in higher education as a matter of public policy. Supporting students' mental health and preventing mental illness requires an evidence-based understanding of the elements that affect students' mental health. Therefore, the primary purpose of this research is to find effective ways to improve students' mental health in higher education. The Design and Development Research (DDR) methodology was used for this investigation. The first part of the research involves the Nominal group technique to present ideas for a solution, and the second part involves how to implement those ideas. While the Fuzzy Delphi technique is used in the second stage of element/solution validation. The participants in both stages of the study were experts in the field who met the researcher's criteria for inclusion. According to the results, seven concrete solutions can be taken to improve students' mental health. At the end of the research, conclusions and suggestions for further research are proposed.
Nutritional Importance of Stirred Yogurt
Authors: Qayyum Sohrab , Rafiq Saima , Hayat Imran , Fahad Muhammad , Tariq Hamza , Waqas Muhammad , Hussain Sheraz
Published: March 2023

Yogurt is a nutrient-rich food product obtain by bacterial fermentation of milk. Recently, numerous studies have been reported its tremendous health effects through fortification and addition of different fruits provides several nutrients which may help to upgradation of health of vulnerable groups. Fruits yogurt is excellent source of essential amino acids, calcium, vitamin D, riboflavin, vitamin B6 and vitamin B12. It promotes gut microbial population as carrier of probiotics which control intestinal infections reduce the serum cholesterol levels and lactose intolerance and reduce the chance of cancer. Yogurt is a functional food, preventive medicine, and residence treatment in the new times requires persistent and transparent public education. This review paper highlighted the importance of fortification of indigenous fruits to makes fruits yogurt.
Genetic Analysis and Heterosis Studies in 5×5 Diallel Crosses of Maize under the Meteorological Conditions of Rawalakot
Authors: Rehman Shafiq- Ur- , Iqbal Awan Shahid , Ilyas Muhammad , Shahzad Muhammad
Published: March 2023

This experiment was performed to evaluate heterosis and combining ability of morphological traits in maize (Zea mays L.). The experiment was arranged in randomized complete block design (RCBD) with three replicates. Twenty maize hybrids were obtained by 5×5 complete diallel crosses in first year and were evaluated for plant attributes like plant height, ear height, ear leaf area, flag leaf area, days to 50% silking, days to 50% pollen shed, anthesis-silking interval (ASI), no. of leaves per plant, no. of branches per tassel, no. of kernel rows per ear and kernels per row, 1000-kernel weight, shelling percentage, grain plus biological yield per plant and harvest index in second year. Among the crosses NCEV-4 × NCEV-3 (462.70g) showed maximum 1000-kernel weight, followed by NCEV-3 × EV-70040 (451.33g), while highest grain yield per plant was recorded for NCEV-4 × NCEV-3 (152.97g), followed by NCEV-3 × EV-70040 (145.10g). Maximum and highly significant heterosis and heterobeltiosis was found in cross NCEV-1530-11 × HNG (70.49 and 67.54), followed by HNG × EV-70040 (65.57 and 56.39) and HNG × NCEV-1530-11 (64.14 and 61.3), rest of the crosses also showed positive and highly significant heterosis and heterobeltiosis for grain yield per plant. Among the parents NCEV-3 has best GCA for grain yield (4.30) while cross NCEV-3 × NCEV-4 has best SCA for grain yield per plant (18.10) and could be used in hybridization for yield improvement.
Media Freedom and Professional Criteria through an Analysis of Daily News Broadcasts on the National Televisions in the Republic of North Macedonia
Authors:   South East European University – Faculty of Languages, Cultures and Communication, Tetovo, the Republic of North Macedonia, Siljanovska Liljana
Published: March 2023

Freedom of speech and expression as one of the fundamental human rights in conditions of a lower degree of democratization of a society increasingly create a state of media dysfunction, informative and analytical reduction and a phenomenon of cognitive atrophy of media messages, especially in the formation of public opinion about significant social issues of political, economic and cultural background. Freedom and responsibility, being two sides of a process in the functioning of the media conditioned by the application of professional standards and criteria, reflects the media culture that influences the formation of public opinion among the audience. The purpose of this paper is to analyze the factors of the development of professional standards and criteria as a significant communication phenomenon that determines the democratic capacity of the contemporary communication reality and the pluralism of citizens’ interests. The paper methodologically focuses on the analysis of the central daily news broadcasts which are justified for several reasons. The first reason manifests their representation of a concentrated form of realizing the informative function of the media. The second reasons manifests their high rating compared to other programs and is broadcast in prime time, in the periods when television has the most viewers. Attitudes and opinions, among other things, will be probed through interviews with journalists and expert public in the media sphere.
IMPLEMENTASI MODEL BLENDED LEARNING DAN MEDIA GOOGLE CLASSROOM TERHADAP HASIL BELAJAR EKONOMI SISWA SMA
Authors: Yuliawati Devy , Hidayati Umi , Etika Erdyna Dwi
Published: March 2023

Tujuan penelitian ini adalah 1) untuk mengetahui hasil belajar mata pelajaran Ekonomi sebelum menggunakan model pembelajaran blended learning menggunakan google classroom terhadap hasil belajar siswa pada mata pelajaran ekonomi, 2) untuk mengetahui hasil belajar mata pelajaran Ekonomi sesudah menggunakan model pembelajaran blended learning menggunakan google classroom terhadap hasil belajar siswa pada mata pelajaran ekonomi.Penelitian ini merupakan penelitian eksperimen. Desain penelitian yang digunakan yaitu One Group Design. Populasi kelas X IPS sebanyak 140 siswa, sedangkan sampel yang digunakan kelas X-IPS 2 sejumlah 35 siswa dengan menggunakan teknik Simple Random Sampling. Teknik pengumpulan data dengan metode tes, dokumentasi. Teknik analisis data menggunakan analisis data statistik t-tes.Berdasarkan hasil belajar nilai siswa menunjukkan nilai rata-rata 71 sebelum menggunakan model pembelajaran blended learning menggunakan google clasroom dan nilai rata-rata 81 sesudah menggunakan model pembelajaran blended learning menggunakan google clasroom, berdasarkan analisis diketahui taraf signifikan 5% untuk Sig. (2 tailed) 0,000 < 0,05 yang berarti H0 ditolak dan Ha diterima. Sehingga “Ada perbedaan hasil belajar siswa sesudah menggunakan model pembelajaran blended learning menggunakan aplikasi google classroom terhadap hasil belajar siswa pada mata pelajaran ekonomi kelas X IPS SMAN 1 Rejoso Kabupaten Nganjuk Tahun Pelajaran 2022/2023”
PENERAPAN STRATEGI PROMOSI MARKETING MEDIA SOSIAL DI PT.CAHAYA SAMUDRA SHIPYARD
Authors: Sentosa Ko Albert
Published: March 2023

Kebijakan suatu perusahaan maupun industri sangat diperlukan untuk meningkatkan produktivitas, efisiensi dan pendapatan. Tujuan dari proyek ini adalah untuk membantu meningkatkan penjualan mitra. Dengan menyebarkan brosur online, untuk meningkatkan informasi masyarakat tentang mitra, dan menggunakan media online untuk memasarkan produk mitra. Dengan mengimplementasi beberapa startegi yang dianalisa oleh penulis, dapat disimpulkan manfaat yang akan dicapai dalam proyek ini adalah Membantu meningkatkan penjualan pada mitra dan Membantu mitra untuk mengetahui pentingnya promosi melalui media online.
PENGARUH EFFECTIVE TAX RATE, MEKANISME BONUS, DAN TUNNELING INCENTIVE TERHADAP TRANSFER PRICING (Studi Empiris pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Tahun 2017- 2021)
Authors: Hertanto Andika Dwi , Marundha Amor , Eprianto Idel , Kuntadi Cris
Published: March 2023

Penelitian ini bertujuan untuk mengetahui Pengaruh Effective Tax Rate, Mekanisme Bonus, dan Tunneling Incentive terhadap Transfer Pricing (Studi Empiris pada perusahaan Manufaktur yang terdafar di Bursa Efek Indonesia Tahun 2017 – 2021). Data yang digunakan dalam penelitian ini adalah data sekunder berupa laporan keuangan tahunan yang diperoleh melalui website resmi www.idx.co.id. Teknik pengambilan sampel yang digunakan adalah Puposive Sampling sehingga diperoleh 11 perusahaan dari 193 perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) dan jumah observasi sebanyak 55 sampel data. Metode analisis yang digunakan adalah Regresi Linear Berganda dengan bantuan Eviews 9. Hasil penelitian menunjukkan bahwa Effective Tax Rate berpengaruh positif dan siginifikan terhadap Transfer Pricing, Mekanisme Bonus berpengaruh negatif tetapi tidak signifikan terhadap Transfer Pricing, dan Tunneling Incentive berpengaruh negatif tetapi tidak signifikan terhadap Transfer Pricing.
ANALISIS BRAND IMAGE SEBAGAI VARIABEL MEDIASI ANTARA PENGARUH HARGA DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN (Studi Kasus pada Mahasiswa Pengguna Produk Xiomi di Yogyakarta)
Authors: Triana Dewi , Hidayat Ruli
Published: March 2023

Tujuan penelitian ini untuk mengetahui bagaimana pengaruh harga, promosi dan brand image sebagai variabel mediasi terhadap keputusan pembelian produk handphone pada mahasiswa pengguna produk Xiaomi di Yogyakarta.

Metode penelitian menggunakan data kuntitatif dimana peneliti berusaha untuk menemukan pengaruh secara langsung dan tidak langsung dari tiap variabel yang diteliti. Penelitian ini menggunakan teknik analisis jalur (path analysis)

Kesimpulan bahwa harga berpengaruh tidak signifikan terhadap keputusan pembelian handphone Xiaomi pada mahasiswa di Yogyakarta, akan tetapi harga berpengaruh signifikan terhadap brand image, sedangkan promosi berpengaruh signifikan terhadap keputusan pembelian handphone Xiaomi pada mahasiswa di Yogyakarta, akan teapi promosi berpengaruh tidak signifikan terhadap brand image handphone Xiaomi bagi mahasiswa di Yogyakarta. Sementara brand image berpengaruh signifikan terhadap keputudan pembelian handphone Xiaomi pada mahasiswa di Yogyakarta. Sedangkan harga dan promosi secara langsung tidak berpengaruh terhadap keputusan pembelian melalui brand image handphone Xiaomi pada mahasiswa di Yogyalarta.
MOTIVASI DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PADA CV. INSAN MANDIRI
Authors: Haryono Haryono
Published: March 2023

Perusahaan akan berusaha untuk mencapai tujuan dengan efektif dan efisien, efektif adalah (tentang usaha, tindakan) yang dapat membawa hasil, sedangkan efisien berarti mampu menjalankan tugas dengan tepat dan cermat Keunggulan suatu perusahaan bisa dicapai melalui beberapa faktor. Salah satu faktor tersebut adalah kemampuan internal perusahaan ataupun melalui sumber daya yang dimiliki perusahaan. Dalam hal ini sumber daya manusia butuh motivasi dan disiplin kinerja agar bisa mengembangkan bakat diri serta mengubah pola pikir yang monoton menjadi jiwa yang inovasi, tidak menutup kemungkinan faktor usia, pendidikan serta lamanya bekerja menjadi faktor kendala seseorang mencapai tingkat kinerja yang efektif, tetapi peran seorang pimpinan adalah ujung tombak dalam merubah pola pokir sumber daya manusia yang ada, motivasi dan disiplin sangat berpengaruh yang dalam untuk seseorang melakukan pekerjaannya maka daripada itu harus saling sadar diri dan mau berusaha akan perubahan diri sendiri untuk menjadi sumber daya manusia yang efektif dan efesien dan dibanggakan oleh semua pimpinan dan teman sejawat, Manusia tidak akan menjadi seseorang  yang hebat jika tidak ada nasehat dan penuntun arah kehidupan dari orang lain.
PENGARUH BUDAYA ORGANISASI DAN GAYA KEPEMIMPINAN TERHADAP KINERJA ORGANISASI PADA BADAN PENDAPATAN DAERAH (BAPENDA) PROVINSI SUMATERA BARAT
Authors: Meirina Elsa , Eflin Niki
Published: March 2023

Tujuan dari penelitian ini adalah untuk memberikan bukti empiris pengaruh strategi terhadap gaya kepemimpinan dengan kinerja organisasi pada Badan Pendapatan Daerah (Bapenda) Provinsi Sumatera Barat. Populasi dalam penelitian ini adalah 50 orang karyawan yang bekerja di Badan Pendapatan Daerah (Bapenda) Provinsi Sumatera Barat. Teknik pengambilan sampel total. Total sampling adalah teknik non-probability sampling dimana peneliti menentukan sampel dengan menggunakan seluruh populasi sebagai sampel. Sampel yang akan digunakan sebanyak 50 orang pegawai Badan Pendapatan Daerah (Bapenda) Provinsi Sumatera Barat. Analisis regresi linier berganda digunakan dalam penelitian ini. Hasil penelitian menunjukkan bahwa Budaya Organisasi dan Gaya Kepemimpinan berpengaruh positif dan signifikan terhadap Kinerja Organisasi pada Badan Pendapatan Daerah (Bapenda) Provinsi Sumatera Barat.
PENGARUH KOMPENSASI DAN BEBAN KERJA TERHADAP KINERJA PEGAWAI PADA PUSKESMAS LUBUK TAROK
Authors: Alfian Alfian , Guswinta Randa
Published: March 2023

Penelitian ini bertujuan untuk mengkaji kompensasi kinerja karyawan di Puskesmas Tarok Lubuk, untuk menguji Beban Kerja kinerja karyawan di Puskesmas Lubuk Tarok; penelitian ini dilakukan di Puskesmas Tarok Lubuk. Metode pengambilan sampel menggunakan total sampling 50 sampel. Teknik analisis data yang digunakan adalah uji validitas, uji reliabilitas, uji normalitas, uji multikolinearitas, uji heteroskedastisitas, analisis regresi berganda, dan uji t. Hasil penelitian menunjukkan bahwa santunan memberikan dampak positif dan signifikan terhadap kinerja karyawan di Puskesmas Tarok Lubuk. Beban kerja tidak berpengaruh terhadap kinerja karyawan di Puskesmas Tarok Lubuk. Jadi dapat disimpulkan bahwa kompensasi diterima, dan beban kerja ditolak
Urban Consolidation in Australia's Four Largest Capital Cities: Tangible Outcomes of Inner-city Apartment Developments and Their Implications for Urban Planners
Authors: Lees Christina
Published: March 2023

Urban consolidation has become dominant practice in metropolitan planning across Australia’s four largest capital cities – Sydney, Melbourne, Brisbane and Perth – as a result of the escalating need to manage rapid population growth and limit urban expansion. The strategic push for higher-density residential dwellings, such as apartment complexes, around strategic infill locations and activity centres is partly in response to the rising demand for more diversity in Australia’s housing stock. Supplementary factors include demographic shifts, cultural changes, and ongoing concerns regarding  housing  affordability,  liveability,  accessibility  and  climate change. Although this style of development has been at the forefront of state government planning agendas for at least a decade, presently little is understood about the outcomes of inner-city apartment buildings, particularly in Perth, as most of  the  research  on  modern  infill  projects  in  Australia  focuses  on  Sydney  and Melbourne.The primary aim of this research is, therefore, to investigate the outcomes of high- Density inner-city apartment developments for residents, the community and urban planners within Australia’s four largest capital cities, with a particular focus on Perth. The research is informed by a review of academic and government literature concerning infill and apartment developments in the specified cities, as well as a case study  of  a  recently constructed  apartment building in one of Perth’s main activity centres, Fremantle. The  study  found  that  state  and  local  governments  are  not  always  achieving  ‘good density’, nor are they developing apartment buildings that engender positive outcomes for both residents and the community. Some of the challenges that must be overcome if this is to change include designing apartments that cater to the needs of a diverse population, getting state governments to provide more support for local councils, and engaging earlier and more effectively with local communities.  The research findings provide council planners with a better understanding of the challenges faced by residents in new apartment buildings, as well as the difficulties of  meeting  community  expectations  and  planning  ‘good  density’,  so  that  future planning policies and urban development can be more suitably informed.
PERAN KEPOLISIAN DALAM PENANGGULANGAN TINDAK PIDANA NARKOTIKA
Authors: Nopra Mulya Hilmy , Wulandari Ratih Agustin , Badri Ainul
Published: March 2023

Penelitian ini bertujuan untukumengetahui bagaimanakah peran Polres Dharmasraya dalam menanggulangi tindak pidanaunarkotika, untuk mengetahui apa saja hambatan Polres Dharmasraya dalam menanggulangi tindak pidanaunarkotika dan untuk mengetahui bagaimanakah upaya Polres Dharmasraya untuk mengatasi hambatan dalam menanggulangi tindak pidana narkotika. Metode yang dipakai pada penelitian ini menggunakan metode penelitian hukum empiris. Hasil penelitian ini menunjukkan bahwa: 1) Peranan Polres Dharmasraya dalam menanggulangi tindak pidana narkotika berupa upaya preventif dan upaya represif. 2) Hambatan yang dihadapi Polres Dharmasraya dalam menanggulangiytindak pidana narkotika yaitu hambatan internal dan hambatan eksternal.
KEKUATAN PUTUSAN MAJELIS PERMUSYAWARATAN RAKYAT (MPR) TERHADAP PEMAKZULAN PRESIDEN DAN/ATAU WAKIL PRESIDEN DI INDONESIA
Authors: Tasyukur  , Muksalmina  , Muksalmina  , Nabhani Yustisi
Published: March 2023

Dalam sejarah Indonesia sebanyak 2 (dua) kali terjadi pemakzulan presiden hal tersebut terjadi sebelum amandemen UUD 1945.  Namun, setelah amandemen UUD 1945 belum pernah terjadi pemakzulan presiden di Indonesia. Proses pemakzulan presiden di Indonesia sesudah amandemen  mempunyai 3 (tiga) tahap, pertama, dari DPR meminta putusan kepada MK atas dugaan pelanggaran yang dilakukan oleh presiden dan/atau wakil presiden, kedua, MK memutuskan atas pendapat DPR, dan putusannya diserahkan kepada DPR, apabila dalam putusan MK bahwa presiden dan/atau wakil presiden terbukti melakukan pelanggaran sebagaimana dalam Pasal 7A UUD 1945, maka DPR melakukan sidang paripurna, untuk mengajukan kepada MPR, ketiga, MPR melakukan sidang paripurna setelah menerima usulan dari DPR, MPR melakukan rapat paripurna yang harus dihadiri sekurang-kurangnya ¾ dari jumlah anggota dan mendapat persetujuan 2/3 dari jumlah anggota yang hadir. Artinya bahwa MPR dalam memberikan putusan harus secara voting. Dengan demiki, terjadi konflik norma antara Pasal 1 ayat (3) dengan Pasal 7B UUD 1945, dikarenakan dalam hal ini kekuatan putusan hakim tidak mengikat, yang keputusan mengikat berada di MPR. Maka menarik untuk dikaji terkait kekuatan putusan MPR dalam hal pemakzulan presiden dan wakil presiden di Indonesia. Metode penelitian yang digunakan dalam penelitian ini adalah yuridis normative. Hasil penelitian ini bahwa MPR mempunyai hak mutlak untuk memakzulkan presiden dan wakil presiden artinya bisa menganulir putusan MK, di saat tidak tercapai persetujuan 2/3 dari ¾ jumlah anggota yang dalam rapat dan presiden dan/atau wakil presiden tidak bisa dimakzulkan dimana MPR yang hadir dalam rapat tidak tercapai dari ¾ jumlah anggota MPR, artinya bahwa peranan politik MPR bisa mengalahkan putusan MK.
TERAPI MODALITAS SENAM LANSIA DENGAN HIPERTENSI DI DESA SUNGAI TANDIPAH RT 3
Authors: Wulandari Dewi Kartika , Oktavia Nor Afni , Noorhasanah Evy
Published: March 2023

Proses penuaan terjadi secara alami dan proses alami tersebut menyebabkan terjadinya berbagai perubahan pada lansia, yaitu dari segi kondisi fisik atau biologis, kondisi psikologis, kondisi sosial, serta kondisi ekonomi. Secara biologis penduduk lanjut usia adalah penduduk yang mengalami proses penuaan yang secara terus menerus yang ditandai dengan menurunnya daya tahan fisik yaitu semakin rentannya terhadap serangan penyakit yang dapat menyebabkan kematian. Hal ini disebabkan terjadinya perubahan dalam struktur dan fungsi sel, jaringan, serta sistem organ. Salah satu senam untuk menjaga kesehatan lansia yang paling murah dan mudah dilakukan adalah senam bugar lansia. Senam Lansia di lakukan untuk mencegah kenaikan tekanan darah. Senam lansia di lakukan selama 1 hari selama 20 menit. Terjadi penurunan pada tekanan darah pada lansia. Senam lansia harus terus di laksanakan berkesinambungan agar tekanan darah lansia tetap terkontral.
Uso de ferramentas online no estudo de mutações
Authors: Laner Blauth Monica , Romano Santin Maria Helena , Martins dos Santos Rafael
Published: March 2023

Uma grande quantidade de informações sobre os genes e genomas estão disponíveis em bancos de dados com possibilidade de utilização em atividades didáticas, permitindo a aproximação dos conceitos abordados em sala de aula das práticas de análise de DNA. Essa abundância de informações, entretanto, pode ser um obstáculo para quem não trabalha com biologia molecular. Aqui propomos um roteiro para a análise de sete sequências mutantes do gene SH3BP2, que causam a doença conhecida como Querubismo. A proposta aborda a identificação de mutações por alinhamento de sequências de DNA e de aminoácidos, o processo de tradução e a análise de mutações.
Paper Models
Authors: Hassunuma Renato Massaharu , Garcia Luan Ednelson Soares , Oliveira Giovanni Augusto Lima de , Garcia Patrícia Carvalho , Acorci-Valério Michele Janegitz , Golim Marjorie de Assis , Messias Sandra Heloisa Nunes
Published: March 2023

A visualização da estrutura tridimensional de biomoléculas pode ser de difícil compreensão para alunos quando o professor se utiliza de recursos bidimensionais tradicionais para apre-sentação delas, como projeções em tela ou imagens impressas. Neste contexto, a utilização de modelos didáticos de papel pode ser um recurso bastante acessível para ser utilizado em sala de aula que, além de motivar, também permite que o aluno estabeleça uma conexão entre a aula teórica e o desenvolvimento da atividade prática.
Biológico e social andam juntos
Authors: Barros Carolina Moraes Martins de , Silva Maíra Batistoni e
Published: March 2023

A participação de mulheres no esporte veio junto com a regulação dos corpos, ou seja, a definição de características que servem para identificar o que é masculino ou feminino e a tenta-tiva de adequar as pessoas, especialmente mulheres, nessa classificação. Nesse contexto, um caso emblemático é o da atleta María-José Martinez Patiño, uma mulher que foi banida das competições esportivas por apresentar cariótipo XY, ainda que não possuísse características físicas ou genitais associadas aos corpos masculinos. Usamos esse caso como motivador para discutir quais são as bases genéticas para a determinação e a diferenciação sexual, além dos cromossomos X ou Y, e como esses conceitos podem ser usados como temas gancho para reflexões na educação básica.
Active case-finding of pulmonary TB in an urban emergency department
Authors: Huaroto L. , Huaman M. A. , Mugruza R. , Ticona C. , Rondan P. L. , Burgos M. , Ticona E.
Published: March 2023

BACKGROUND: The WHO recommends systematic screening of TB in high TB prevalence settings. We evaluated an active case-finding strategy using sputum screening regardless of symptoms in a high TB prevalence Emergency Department (ED) in Peru.METHODS: This was a cross-sectional
study conducted at the Hospital Nacional Dos de Mayo ED, which serves low-income populations in downtown Lima, Peru. Adults presenting to the ED for any reason and able to provide sputum were enrolled. Participants provided one sputum specimen for acid-fast bacilli smear and culture. A second
sputum specimen for Xpert® MTB/RIF testing was collected if the patient was admitted to an ED observation unit.RESULTS: Between September 2017 and March 2018, 5,171 individuals who presented to the ED were approached. Of 2,119 individuals able to provide sputum, 78
(3.7%) participants had a positive culture and/or Xpert result and were newly diagnosed with TB, whereas traditional screening using >2-week cough identified 41 (1.9%) cases (3.7% vs. 1.9%; P < 0.001). Twelve TB cases (15.4%) reported no TB symptoms of any duration.CONCLUSION:
ED-based active case-finding of pulmonary TB using symptom-neutral sputum screening increased TB identification compared to traditional symptom-based screening. Our results align with current WHO recommendation of systematic screening in high TB prevalence areas, which may include ED settings.
Reducing the burden of TB among migrants to low TB incidence countries
Authors: Spruijt I. , Erkens C. , Greenaway C. , Mulder C. , Raviglione M. , Villa S. , Zenner D. , Lönnroth K.
Published: March 2023

BACKGROUND: International migrants to low TB incidence countries are disproportionately affected by TB compared to the native population: migrants are at increased risk for TB transmission and TB disease due to a variety of personal, environmental and socio-economic determinants
experienced during the four phases of migration (pre-departure, transit, arrival and early settlement, return travel).OBJECTIVE: To provide an up-to-date overview of the determinants that drive the TB burden among migrants, as well as effective and feasible interventions to address
this for each migration phase.METHODS: We conducted a literature review by searching PubMed and the grey literature for articles and reports on determinants and interventions addressing migrant health and TB.RESULTS: Lowering the risk of TB transmission and TB disease
among migrants would be most effective by improving the socio-economic position of migrants pre-, during and after migration, ensuring universal health coverage, and providing tailored and migrant-sensitive care and prevention activities.CONCLUSION: In addition to migrant-sensitive
health services and cross-border collaboration between low TB incidence countries, there is a need for international financial and technical support for endemic countries.
Interactive air situation simulator
Authors: Miller-Kopyt Michał , Witczak Andrzej
Published: March 2023

In the present day, simulators play a significant role in training military personnel. They allow, among other things, for practicing combat scenarios that are difficult or outright impossible to execute in reality. Virtual reality technologies are being constantly developed, as are the ways of their interaction with each other and with real objects. This article brings up the topic of interactive distributed simulations, presenting their technological developments as well as the goals of their authors. After the analysis of selected methods of interactive distributed simulations, project assumptions are formulated and interactions occurring between objects in virtual airspace are stated. The last part of the article describes the attempt of creating an interactive air situation simulator in accordance with the formulated assumptions. As a result of the work conducted, it was possible to program a simulator that allows us to study the interactions between radar warning receivers and ground based primary surveillance radars. Not all assumptions have been achieved, most notably full functionality with the DIS standard, however, the project can be further developed, allowing for full compatibility with this standard. Developing a simulator is a process that requires many assumptions, but also trade-offs. With correct assumptions and a standardised way of information exchange between simulators, it is possible to make a web of interoperable simulators. Keywords: aerospace engineering, simulators, radars, distributed interactive simulation
Karate Sports Disciplines from the Spotlight of the Paradigm Shift of Japanese Combat Systems: Analytical Study
Authors: Lozovyy Anatoliy Anatoliy
Published: March 2023

Background: Nowadays, many karate organizations hold their own competitions at various levels, up to and including the world championships. They are positioned as separate sports, although the content, rules and regulations of many of them differ only in details. A large number of similar sports versions of karate interfere with the correct understanding and objective assessment of karate in the modern world. Materials and Methods: Based on 40 years of practical experience in studying and teaching karate and on the results of his own research in 2019-2022, the author presents his point of view on the unification of sports versions of karate based on common systemic features into three separate sports. Like any sport, karate reflects the social phenomenon from which it originated. Using civilization-historical, functional and social approaches, the author suggests that the paradigm shifts in combat systems lead to the emergence of new forms that have deep systemic differences. Accordingly, these differences are also manifested in sports disciplines that have arisen on the basis of these forms. Results: Three forms of karate have a component with pronounced features of modern sport and form three systemically different competitive disciplines: 1) Style (Traditional) karate; 2) General karate; 3) Sports (Olympic) karate. The differences between them stem from the differences between the forms of karate from which they arose. Conclusions: Style, General and Sports karate are sports which require consideration in different paradigms. They are selfsufficient and equal in value and public demand.
Organizing and conducting classes on driving combat vehicles
Authors:   Military Institute  of  Land  Forces  named  after  SagadatNurmagambetov, Almaty, Kazakhstan, Kadirkulov Sh.K. , Sultanov B.A. ,   Military  institute of Land Forces named after SagadatNurmagambetov, Almaty, Kazakhstan
Published: March 2023

Training in driving combat vehicles is an integral part of the field training of troops. Therefore, this study analyzes methodological guidelines and practical tips on practical driving of combat vehicles in preparation for the lesson and during training, as well as the main duties of officials who significantly increase the level of training in military educational institutions of future unit commanders.
Residents’ Perception of the Impacts of Tourism and Satisfaction: Evidence from Zanzibar
Authors: Wambura George , Jan Devi , Maceci Nuru
Published: March 2023

The current research trend in Sub-Saharan Africa suggests only a handful of studies on residents’ perceptions of the impacts of tourism and its associated benefits. Despite tourism being a booming industry in Tanzania, the extent to which tourism development contributes to resident’s satisfaction and their general welfare is not known. This paper sought to fill in the specified knowledge gap by capturing various insights depicting perceived economic, socio-cultural and environmental impacts of tourism in Zanzibar Island, and establish the level of satisfaction on the studied phenomena. To meet the desired aim, a total of 200 respondents were selected strategically from targeted localities in Kiwengwa area to respond to a structured questionnaire. Obtained data were analysed descriptively, and a multiple linear regression was carried out. The regression analysis results indicate that perceived social-cultural and environmental impacts of tourism have significant positive impacts on residents’ satisfaction; while perceived economic impacts of tourism lack significant effect on the satisfaction. Based on these results, the assumptions of the social exchange theory (SET) employed in this paper as a conceptual model are confirmed since the perceived impacts of tourism significantly contributed to residents’ satisfaction with tourism. The results shed light on the need for strategic stakeholder‘s interventions that may boost the tourism industry in the Island, and similar destinations, by considering the triple bottom line aspect of sustainability (economic, socio-cultural, and environmental), and consequently increasing residents’ satisfaction with tourism in their destinations.
The Contribution of Marine Fisheries to Socio-economic Development in Tanzania Mainland: Reflections on the Blue Economy Concept from Selected Coastal Villages
Authors: Ulega Abdallah , Mgaya Yunus , Lokina Razack , Mushy Reguli
Published: March 2023

Marine fisheries, as a sub-sector, may potentially play a significant role to the advancement of socio-economic development in countries that aim to spearhead the concept of ‘blue economy’ in Africa, south of the Sahara, including Tanzania. This paper assesses the contribution of marine fisheries to socio-economic development in Tanzania in terms of livelihood improvement and advancement of the national economy. Data for this paper were captured from a study that involved 1,026 respondents from eight (8) fishing villages in four coastal regions of Tanzania Mainland: Dar es Salaam, Coast, Tanga and Lindi. The study adopted a cross-sectional research design, mixed-methods research approach and triangulation of methods to ensure validity of data. Data were captured using a semi-structured questionnaire, interviews, focus group discussions and personal field observations. Obtained data were complemented with documented input from the Ministry of Livestock and Fisheries and analysed qualitatively and quantitatively. The results indicated that fishing as a primary source of income in coastal communities may contribute to household food security through the consumption of households’ catching. The results also suggested that local fishers have a limited access to resources in the exclusive economic zones (EEZs) and deep-waters due to the continued use of traditional fishing gears and vessels.  It is recommended that local fishers be capacitated to exploit EEZ and deep-sea resources through support to access credit facilities and the provision of modern fishing vessels and appropriate gear. This could pave the way for the development of a fisheries sector based on EEZ and deep-sea resources.
Hypodensities within hematoma predict outcome after spontaneous intracerebral hemorrhage
Authors: Khalil Maryam , Sumaira Nabi  , Amjad Mehmood Khan  , Zeeshan Munawar  , Samar Naik  , Zaid Waqar  , Malik Muhammad Adil  , Mazhar Badshah
Published: March 2023

Background and objective:

Not much is known about the prevalence and significance of hypodensities within hematoma after spontaneous intracerebral hemorrhage (ICH). The objective of this study was to determine the prevalence of hypodensities within hematoma after spontaneous ICH and their significance to predict poor outcome after ICH.

Methods:

This observational cross sectional study was conducted in the Department of Neurology, Pakistan Institute of Medical Sciences, Islamabad, from October 2021 to June 2022. Total 140 patients of acute stroke were included. Inclusion criteria was any patient of >20 years of age with confirmed diagnosis of ICH on imaging, non-traumatic, who presented within 24 hours after onset of symptoms. Data was analyzed by SPSS ver.23.0.

Results:

Total 150 patients were included in the study. The mean age of patients was 52.28 ± 1.29 years. There were 100 (71.4%) males and 40 (28.6%) females. Hypertension was the most common comorbid present in 87 patients (62.1%).55% of patients had on presentation National Institute of Health Stroke Scale (NIHSS) and modified Rankin Scale score of moderate severity. The mean ICH score on presentation was 2.64 +1.26. Hematoma expansion was present in 55(39.3%) patients while interventricular extension was seen in 100(71.4%) patients. Hypodensities were seen in 125(89.3%) patients( p value 0.001). When hematoma volume were compared in both groups it was also significant (p value 0.002).

Conclusion:

We conclude that hypodensities within hematoma are a reliable marker of hematoma expansion after spontaneous ICH. Such reliable marker can be easily employed in resource-poor countries where CT angiography is not available everywhere. The higher NIHSS score and low GCS are significantly associated with hypodensities within hematoma.
STUDY EFEKTIVITAS KEBIJAKAN INOVASI DOKADU (DOKUMENTASI PENGADUAN) DI DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KOTA MAGELANG
Authors: Kumalasari Reta
Published: March 2023

Management of public service complaints is an important part of improving the quality of services provided by the government to the community. The reasons for the importance of complaints include: 1) the public has the right to obtain quality, non-discriminatory public services in accordance with established standards, 2) public complaints are an opportunity for government agencies to evaluate and improve, 3) as government media in providing response to public complaints. To improve services, one of them is by making an innovative breakthrough that makes it easier for the complaints team to resolve problems with public complaints. This innovation is called DOKADU (Complaint Documentation). This study aims to analyze the effectiveness of the DOKADU (Complaint Documentation) innovation policy in resolving public complaints at the Population and Civil Registration Office of Magelang Municipality for a period of 5 years (2017 – 2021). This research uses descriptive qualitative narrative method. The results of the study show that since the implementation of innovations over the last 5 years (2017 – 2021) it shows that there is a tendency for the number of complaints that have been received and handled successfully to increase (99.85%). FAQs (Frequently Asked Questions) that are frequently complained about can be monitored because segmentation/category of complaints can be carried out and ownership of population administration documents increases. This shows that the quality of handling public complaints at the Disdukcapil in Magelang Municipality has increased. This innovation needs to be continuously improved and developed so that it becomes a smart book for the public complaints team. In the future, it is hoped that there will be a software application that assists in documenting complaints, so that population administration services in Magelang Municipality will make the people happier according to the Vision of “Magelang Municipality, namely Magelang is Healthy, Advanced and Happy ".
Clinical Efficacy of Spleen and Yin Prescription in the Treatment of Primary Sjogren Syndrome and Its Impact on Disease Activity
Authors: Zhou Na , Wang Lin , Chen Junjie , Wang Ze , Tao Yanhong , Huang Chuanbing
Published: March 2023

Objective: To study the clinical efficacy of primary Sjogren syndrome and the effect of disease activity. Methods: The 60 patients from January 2021 to January 2022 respectively, and divided into two groups according to random numbers, hydroxychloroquine sulfate, 30 patients, clinical effect combined with hydroxychloroquine sulfate, inflammatory index, complement levels, and immunoglobulins (ESR, RF, CRP, C3, C4, IgG, IgA, IgM), ESSDAI, ESSPRI, and adverse effects. Results: The total response rate of the two groups was 86.67% (26/30) and 73.33% (22/30), respectively, comparing with the treatment group (P <0.05). Comparison between groups found that no differences in CRP, C4, IgA, and IgM were significant (P>0.05). After treatment, peripheral ESR, RF, IgG decreased, complement C3 levels increased (P <0.05), the ESSDAI score and ESSPRI score of the two groups also decreased (P<0.05). On the Traditional Chinese medicine symptom integral, the treatment group had better results in improving dry mouth, dry throat, dry eyes, dry skin, five upset heat, and joint pain(P<0.05), and no adverse reactions were found in either group. Conclusion: The treatment group can effectively improve the clinical efficacy, reduce the level of inflammatory indicators and disease activity, and see no obvious adverse reactions, which can be effectively used in clinical practice.
A Brief Analysis on the Modulation Effect of Ba Duan Jin on Non-Motor Symptoms of Parkinson’s Disease
Authors: Li Kefan , Li Jun
Published: March 2023

Parkinson’s disease (PD) is a common neurodegenerative disease in middle-aged and elderly people. The non-motor symptoms of PD, such as depression and anxiety, are often ignored in the face of typical motor symptoms such as tremor and bradykinesia. Non-motor symptoms in PD will not only increase the burden of patients, affect the quality of life, but also reduce the effect of PD drug treatment. A vicious circle is formed. At present, PD cannot be cured. Drugs are the first-line treatment, but long-term use in clinical practice will bring various side effects. Clinical studies have shown that Ba duan Jin as an adjuvant treatment can improve the non-motor symptoms of PD and delay the progression of PD. However, the regulatory mechanism of Ba duan jin on non-motor symptoms of PD is still unclear, which needs to be further elaborated in combination with the theory of traditional Chinese medicine.
The Revival of the Quadrilateral Security Dialogue: Causes and Characteristics
Authors: Ba Chunying
Published: March 2023

The content of this paper is mainly divided into the following four parts: First, the development of the Quadrilateral Security Dialogue is sorted out; Secondly, explore the reasons for the resumption of the Quadrilateral Security Dialogue; Third, analyze the characteristics of the new Quadrilateral Security Dialogue. Finally, this paper believes that the United States, Japan, India and Australia have formed a Quadrilateral Security Dialogue mechanism based on their respective interests, but the resumption of this mechanism is not only from the continuous cooperation of the four countries, but also from the internal contradictions of the international system. The Quadrilateral Security Dialogue mechanism is deepening and the cooperation issues are also expanding. The containment and impact of Quad on China cannot be ignored.
Transition of Countries to Currency and Trade Sustainable International Cooperation on the BRICS Platform
Authors: Bryndin Evgeniy
Published: March 2023

The transition to monetary and trade sustainable cooperation within the BRICS can be carried out on the basis of the energy economic equivalent of the national currencies of sovereign states. The International Monetary Index will link the existing commodity masses of states with national currencies. The creation of two-circuit national monetary and financial systems will create conditions for the evolutionary transition of budget formation. Double-circuit monetary and financial systems will bind national currencies to energy economic equivalents and goods. An interim measure of the national currency due to the energy economic equivalent and a group of goods with both commodity and monetary properties creates their currency value. This makes it possible to estimate their value in the energy economic equivalent. The energy economic equivalent can become a meter of the intrinsic value of any payment means. The economic reserve base, expanded at the expense of groups of goods, makes it possible to create a stable basis for strengthening national currencies in the system of domestic, regional and international settlements, maintaining their stability. It is possible to connect the financial and real sectors of the international economy of sovereign states through the BRICS investment international bank. This will allow the generation of long and cheap financial resources by issuing securities and digital financial assets secured by a group of goods with foreign exchange value. National currencies will become full-fledged, tied to the amount of those resources that are in the provision of the BRICS investment international bank.