bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudio de vida real sobre la eficacia del esquema AIDA PETHEMA en leucemia promielocítica aguda, datos de un centro universitario de referencia
Authors: Barros Fuenmayor Valeria , Manrique Sánchez Esteban , Avendaño Pérez Pablo Andrés , Fiorentino Gómez Susana , Quijano Gómez Sandra Milena , Arévalo Zambrano Mónica , Ballesteros-Ramírez Ricardo , Victoria Herrera María
Published: July 2023

Objetivo: analizar las características clínicas, eficacia del esquema AIDA PETHEMA, respuesta a la inducción, supervivencia global y supervivencia libre de evento en pacientes diagnosticados con leucemia promielocítica aguda (LPA) en una institución de cuarto nivel durante 10 años. Materiales y métodos: Recolección de datos: se ejecutó una búsqueda en las bases de datos con revisión de las historias clínicas en el sistema de información de historia clínica del Hospital Universitario San Ignacio. Se realizó un análisis retrospectivo de los pacientes adultos que fueron diagnosticados con LPA en el periodo 2010 a 2020. Se recolectaron variables clínicas de forma cuantitativa, categórica o de intervalo, según su clasificación. Se evaluó el número de pacientes que alcanzó remisión completa luego del protocolo de inducción. Se utilizó el método de Pardo C. et al. (2015) modificado para ajustar el valor de aquellos pacientes en los cuales existió pérdida en el seguimiento.
Frecuencia de alteraciones germinales en genes de riesgo alto/moderado para riesgo de cáncer de mama hereditario : estudio multicéntrico en población no seleccionada
Authors: Mantilla Durán William Armando , Sierra Díaz Diana Carolina , Morel Adrien , Contreras Nora , Angulo Aguado Mariana , Balaguera Valentina , Llinás Caballero Kevin , Munévar Isabel , Borras Osorio Mariana , Lema Mauricio , Lema Camila , Restrepo Carlos , Fonseca Dora Janeth , De la Peña Jairo , Rubiano Wilson , Idrobo Henry , Trujillo Daniela , Serrano Norma , Orduz Ana Isabel , Rojas Gustavo , Londoño de los Rios Paula Andrea , Manneh Ray , Quintero Catalina , Cabrera Rodrigo , González Jaime , Lopera Diego
Published: July 2023

Objetivos: el cáncer de mama (CM) es la neoplasia más frecuente en Colombia. La supervivencia global a 5 años es <80 %, siendo el país latinoamericano con el peor pronóstico. Las estrategias preventivas como la identificación de población con riesgo de síndrome de CM y ovario hereditario (HBOC), tiene el potencial de reducir la incidencia de CM y disminuir los diagnósticos en estadios avanzados. La mayoría de los estudios publicados en población colombiana, han evaluado variantes reportadas como fundadoras, denominadas el “Perfil Colombia” o en población seleccionada con alta probabilidad de presentar HBOC. En este estudio realizamos un análisis genómico a gran escala para evaluar mutaciones germinales en pacientes con CM no seleccionadas, en múltiples regiones del país.
Enfermedad crónica activa por virus de Epstein-Barr: un reto clínico
Authors: Peñuela Bermejo Rafael Alejandro , Fuentes Lacouture María Cynthia , Hernandez Indira , Martínez Humberto
Published: July 2023

Objetivo: describir y comparar la experiencia en tres casos de CAEBV multicéntricos, características clínicas, patológicas, tratamiento y desenlaces. Materiales y métodos: estudio descriptivo retrospectivo de tres historias clínicas con diagnóstico de CAEBV.
Valor pronóstico de la relación neutrófilos/linfocitos en pacientes con cáncer de mama operable con enfermedad residual posquimioterapia neoadyuvante
Authors: Cuello López Javier , Fidalgo Zapata Ana , López Agudelo Laura , Llinás Quintero Néstor
Published: July 2023

Introducción: la respuesta a la quimioterapia neoadyuvante en pacientes con cáncer de mama, es un excelente marcador pronóstico de desenlaces a corto y mediano plazo y es uno de los objetivos primarios en la mayor parte de los estudios recientes que evalúan la utilidad de la quimioterapia neoadyuvante. La respuesta inmune peritumoral es un factor pronóstico y predictivo de supervivencia en pacientes con cáncer de mama. La estimulación de vías de señalización inmunes en sangre periférica puede ser un reflejo de la respuesta inmune peritumoral y por ende ser un determinante en el pronóstico de las pacientes con cáncer de mama tratadas con quimioterapia neoadyuvante.Objetivo: evaluar el valor pronóstico de la relación neutrófilos/linfocitos (NLR) en sangre periférica previo al tratamiento en pacientes con cáncer de mama operable con enfermedad residual posterior a la quimioterapia neoadyuvante. Pacientes y métodos: estudio observacional retrospectivo en pacientes con cáncer de mama tratadas con quimioterapia neoadyuvante en la Fundación Colombiana de Cancerologia Clinica Vida entre los años 2013 a 2016. Se describen características demográficas, clínicas y patológicas, tasas de respuesta a la quimioterapia neoadyuvante, la asociación entre NLR con los parámetros clínico patológicos y el valor de NLR como variable pronóstica de supervivencia.
Déficit severo de factor V en un lactante con hemorragia cerebral espontánea tratado con trasplante hepático: a propósito de un caso
Authors: Garay Barbosa David José , Martinez Juan Camilo
Published: July 2023

Introducción: la deficiencia congénita del factor V (FVD) es un trastorno hemorrágico raro causado por mutaciones en el gen FV que reduce cuantitativamente los niveles plasmáticos de FV, cuya incidencia estimada es de 1 en 1.000.000 en la población general y se hereda con un patrón autosómico recesivo. La enfermedad es clínicamente heterogénea; las complicaciones potencialmente mortales como las hemorragias del sistema nervioso central (SNC) no son comunes (6-8 %), ocurren principalmente en los primeros meses de vida y se limitan a pacientes con déficit grave de FV.
Rendimiento operativo de la escala SCAN como herramienta de tamización nutricional para identificar riesgo de desnutrición en población infantil con cáncer en la Fundación HOMI, Colombia. Fase 2
Authors: Macana Muñoz Saúl David , Pinzón Espitia Olga Lucía , Pardo González Carlos Alberto
Published: July 2023

Objetivo: evaluar el rendimiento operativo de la versión en español de la escala de tamización nutricional para el cáncer infantil (SCAN) como parte del proceso de validación del instrumento en el contexto de un hospital de alta complejidad en la ciudad de Bogotá, Colombia. Materiales y métodos: estudio de validación de escala diagnóstica. Población de estudio: niños y niñas desde el nacimiento hasta los 17 años y 11 meses de edad, hospitalizados en el Centro de Cáncer Infantil de la Fundación Hospital Pediátrico la Misericordia (HOMI) en Bogotá, Colombia, quienes son atendidos por el servicio de Oncohematología de la Institución.
Concordancia entre la prueba de puntuación de recurrencia de 21 genes y modelos clínico patológicos predictivos en pacientes con cáncer de mama temprano en un centro oncológico en Colombiag
Authors: Luján Mauricio , Morán Diego , Preciado Beatriz , Lema Camila , Fernández María José , Egurrola Jorge , Pineda Mateo , Lema Mauricio
Published: July 2023

Objetivo: La prueba genómica de recurrencia de 21 genes (Oncotype DX, Genomic Health) (ODx®) permite determinar la utilidad de quimioterapia adyuvante en pacientes con cáncer de mama temprano tipo luminal. De forma segura se puede omitir la quimioterapia adyuvante en pacientes con un puntaje de riesgo bajo (RB). También se han desarrollado otros modelos predictivos basados en variables clínicas e histopatológicas estándar. Estos incluyen las ecuaciones de Magee (EM), el modelo Predict (MP) y la puntuación del nomograma de Tennessee (NT). El objetivo de este estudio es evaluar la concordancia entre ODx® y los modelos predictivos.
Características clínicas y supervivencia de cáncer de pulmón de células no pequeñas EGFR positivo
Authors: Ramos Pedro , Athenas Ramos María , Silva Diana
Published: July 2023

Objetivos: 1) Describir las características clínicas de los pacientes con cáncer de pulmón EGFR positivo tratados con inhibidores de la tiroxina-kinasa, 2) Describir la supervivencia global de los pacientes con cáncer de pulmón EGFR positivo tratados con inhibidores de la tiroxina-kinasa y, 3) Describir la supervivencia libre de progresión de los pacientes con cáncer de pulmón EGFR positivo tratados con inhibidores de la tiroxina-kinasa. Materiales y métodos: se trata de un estudio observacional descriptivo, retrospectivo. Se realiza con la información de la Clínica Oncocare durante el periodo comprendido entre el 1° de septiembre de 2009 al 30 de marzo de 2022. Se realizaron análisis descriptivos usando medidas de tendencia central, ubicación y dispersión para las variables continuas y frecuencias absolutas y relativas para las variables categóricas. Se construyeron curvas de supervivencia por el método de Kaplan-Meier.
¿Cambio de paradigma en glioblastoma, una realidad actual?
Authors: Villegas Mejía Carlos Raúl , Rojas Uribe Gustavo Adolfo , Villegas Jaramillo Manuel , Villegas Jaramillo Pedro
Published: July 2023

Introducción: el glioblastoma (GBM) de pronóstico adverso y alta letalidad hasta la introducción del protocolo Stupp con adyuvancia de solo seis meses de temozolamide, es considerado el tratamiento estándar definido como el primer esquema para aumentar la sobrevida global.Objetivo: describir el comportamiento clínico, epidemiológico y de resultados terapéuticos del GBM con la aplicación del protocolo Stupp para luego hacer un análisis de diferentes variables en sobrevida y demostrar la necesidad actual de cambio de adyuvancia más prolongada, buscando definir el periodo mínimo que genere iguales o mejores resultados en sobrevida frente al estándar de seis meses de temozolamide en adyuvancia.
Asociación entre la fragmentación de la atención en salud y la supervivencia global a tres años en pacientes con cáncer colorrectal y cáncer de mama pertenecientes al régimen contributivo en Colombia
Authors: Buitrago Giancarlo , Patiño Benavidez Andrés Felipe , Eslava-Schmalbach Javier Hernando , Junca Edgar Germán , Gamboa Garay Oscar , Saldaña Espinel Laura Estefanía , Guevara Cruz Oscar Alexander , Caycedo Beltrán Rubén Ernesto , Sánchez Pedraza Ricardo , Rozo Agudelo Nicolás , Bonilla González Carlos Eduardo
Published: July 2023

Objetivo: dentificar la asociación entre la fragmentación de la atención en salud y la supervivencia global a tres años en pacientes con cáncer colorrectal y cáncer de mama en Colombia
SOME ISSUES OF IMPROVING THE LEGISLATION OF THE HYDROGEN ENERGY FIELD IN UZBEKISTAN
Authors:   Tashkent State University of Law, Rajabov Nariman
Published: July 2023

The article describes the nature and importance of hydrogen energy, as well as the policy of our country in this regard and the importance of this energy source in the energy system. Proposals have been put forward. It is significant that the most advanced foreign experience on the issue of hydrogen energy has been studied, and proposals and recommendations have been developed for its development in our country and the improvement of the current legislation in this regard. In addition, various ideas have been put forward in terms of the recognition of scientists in this field and the understanding of the advantages of hydrogen energy by mankind. In addition, the advantages of using hydrogen as a fuel in this area are fully disclosed. This, in turn, creates the basis for the development of this energy source. In this context, the essence of this article is that this element is considered more expensive than other hydrocarbons due to its production in large quantities. In addition, the significance of the need to solve environmental issues in this area has been researched.
А.I. ISHANOV – PROMINENT UZBEK SCIENTIST AND STATESMAN
Authors:   Tashkent State University of Law, Karakhodzhaeva Dilorom
Published: July 2023

The article is dedicated to the memory of the teacher and mentor, the outstanding legal scholar Atabay Ishanovich Ishanov, as a tribute and honor for his many years of work in training highly qualified lawyers and great achievements in research activities to improve national statehood and develop the legal science of the country. In addition to the main biographical data, the Alma mater, that is, the years of study, the formation as a scientific researcher in the field of the history of the creation and development of national statehood in Uzbekistan, as well as the resolution of many theoretical problems of the nationwide state, which were embodied in the scientific works of A.I. Ishanov, a number of articles in the republican and allied press, in his editorial activities in relation to major scientific publications. Particular attention is paid to the scientific activity of A.I. Ishanov in the training of highly qualified scientific personnel from local nationalities (Uzbeks, Turkmens, Karakalpaks, Tajiks, Kirghiz, Kazakhs, etc.), characterizing A.I. Ishanov as an internationalist scientist. In addition to the recognition of Atabay Ishanovich Ishanov as a great figure in legal science, a recognized, well-known scientist, public figure, teacher, and mentor of all lawyers in Uzbekistan, his life is presented as a role model, a kind of standard in everything, from behavior in everyday life to legislative activity, in which it is surprising that he combined the best human qualities with excellent professionalism. In general, it should be noted the need for this article is designed to serve as a role model and a service in the preparation of the younger generation.
THE ROLE AND IMPORTANCE OF OBJECTS AND ENTITIES IN ENERGY SECURITY
Authors:   Tashkent State University of Law, Khaitov Panji
Published: July 2023

In this article, opinions were expressed on the improvement of regulatory legal acts related to the system depending on the concept of the role and importance of objects and entities in energy security and their analysis. Also, the most important issues related to the further development of the theory of the law of ecology of the concept and system of the place and significance of objects and entities in energy security were analyzed. The role and significance of objects and entities in energy security, the problems of regulating the sources of energy law, and the issues of legal regulation of energy efficiency and rational use in the system of natural resources were studied in the framework of scientific research from the point of view of environmental law. In the energy sector, public administration is carried out in certain forms and methods. The role and significance of objects and entities in energy security legal relations related to the issues of legal regulation of improving and rational use of energy efficiency, the content of norms aimed at their regulation, the essence and problems of their application in practice, the management system in the field of energy use and protection, and the powers of management bodies are researched and implemented.
LEGAL INSTRUMENTS OF THE PROTECTION OF FOREIGN INVESTMENT IN ACCORDANCE WITH THE PROVISIONS OF THE BILATERAL INVESTMENT AGREEMENT: EXPERIENCE OF THE REPUBLIC OF UZBEKISTAN
Authors:   Leading consultant of the Ministry of Justice, Valeev Artur
Published: July 2023

The author of the article analyzes the current state of bilateral investment agreements on mutual protection and promotion of investments to which the Republic of Uzbekistan is a signatory (previously adopted provisions, innovations, and analytical and scientific works are also mentioned). In particular, the author focused the Legislator’s attention on investment activities, ensuring proper protection of investments, the importance of investments in modern realities, the role of state bodies in regulating investment activities aimed at economic growth, and creating additional opportunities for foreign investors. At the same time, the author indicates that at a time when the procedure for implementing standard investment agreements has already been developed in many countries, such practice in Uzbekistan has not yet acquired so much importance, which is also determined by the lack of a legal and scientific basis, which in turn leads to gaps, ambiguities, and misunderstandings of the importance of legal regulation. Also, the paper reflects the main catalytic aspects of the application of the principles of international investment law and various mechanisms for the protection of foreign investments in order to prevent the further course of a foreign investor in arbitration. The article takes into account the role of international investment agreements, especially bilateral ones, which consist of guaranteeing the stability of the regime for foreign investors, providing them with appropriate incentives, and the common interests of both foreign investors in capital and the countries where investments are made. In order to further develop the direction of developing and implementing modern mechanisms for the protection of foreign investors and the state, the researcher studied foreign experience, scientific papers, and precedents and made appropriate proposals and recommendations on drafting or amending bilateral investment agreements to which the Republic of Uzbekistan is a party.
RELATÓRIO DE OBSERVAÇÃO DE ESTÁGIO EM PSICOLOGIA ORGANIZACIONAL: COMPREENDENDO O MODELO DE GESTÃO ESTRATÉGICA FAMILIAR E DIAGNÓSTICO INSTITUCIONAL
Authors: Silva Rosa Kioko Iida da , Tissen Mônica Rogalsky , Machado Regina Maria , Silva Diego da
Published: July 2023

O presente artigo tem por objetivo o relato de experiência de estágio em Psicologia Organizacional realizado em uma empresa localizada na cidade de Curitiba, com modelo de gestão familiar. Foram realizadas observações sistemáticas no local afim de se obter um diagnóstico institucional e um possível projeto de intervenção. O empreendedorismo familiar tem sua importância na qual gera um grande número de vagas de trabalho, potenciando as pessoas a uma sociedade e com isso sua sustentabilidade diária, dela e de seus familiares. Saber da importância de abrigar novos profissionais como no caso de um psicólogo organizacional que irá atuar em questões motivacionais, criando um clima organizacional que seja harmonioso facilitando o crescimento profissional dos colaboradores, através de promoções de atividades em que haja interações no campo profissional e familiar. Outra função que cabe ao Psicólogo organizacional o de gerenciar e minimizar os conflitos que porventura venham a ocorrer no local do trabalho, também atuar junto ao RH, em relação às promoções e/ ou contratações de colaboradores. E em caso de demissões é importante o acompanhamento do mesmo a fim de que seja dado o feedback em relação ao fato, assim como contribuir para a instituição do clima organizacional da empresa.
A IMPORTÂNCIA DA PREVENÇÃO E DETECÇÃO PRECOCE DO CÂNCER DE PELE
Authors: Barros Poeys Nathalia , Parente Bianca Pecly
Published: July 2023

A pele apresenta um papel imprescindível na proteção corporal, visto que age como uma barreira física no que diz respeito a agentes externos e na regulação da temperatura corporal. Porém, a exposição frequente e prolongada a radiação ultravioleta pode vir a causar danos à pele, como eritema, fotoenvelhecimento, queimaduras e até mesmo neoplasias cutâneas. Diante disso, o câncer de pele, atualmente, é definido como o de maior incidência do mundo, e, consequentemente, considerado um grave problema de saúde pública no Brasil. Nesse viés, o câncer de pele possui inúmeros fatores de risco, em que ganha ênfase cabelos, olhos e peles mais claros, consumo de álcool e tabaco, processos dermatológicos irritativos crônicos e radiações ionizantes. Nesse contexto, torna-se cada vez mais necessário a adoção de medidas associadas a ações de promoção de saúde, no que se refere à pele, a prevenção de agravos dermatológicos e a recuperação da saúde cutânea, respectivamente. Além disso, é necessário o conhecimento e aperfeiçoamento de técnicas de excisão cirúrgica para tratamento do câncer de pele já instalado.
Rethinking the role of transport and photochemistry in regional ozone pollution: insights from ozone concentration and mass budgets
Authors: Qu Kun , Wang Xuesong , Cai Xuhui , Yan Yu , Jin Xipeng , Vrekoussis Mihalis , Kanakidou Maria , Brasseur Guy P. , Shen Jin , Xiao Teng , Zeng Limin , Zhang Yuanhang
Published: July 2023

Abstract. Understanding the role of transport and photochemistry is
essential to mitigate tropospheric ozone (O3) pollution within a
region. In previous studies, the O3 concentration budget has been
widely used to determine the contributions of two processes to the
variations of O3 concentrations. These studies often conclude that
local photochemistry is the main cause of regional O3 pollution;
however, they fail to explain why O3 in a targeted region is often
primarily derived from O3 and/or its precursors transported from the
outside regions, as reported by many studies of O3 source apportionment.
Here, we present a method to calculate the hourly contributions of
O3-related processes to the variations of not only the mean O3
concentration but also the total O3 mass (the corresponding budgets
are noted as the O3 concentration and mass budget, respectively) within
the atmospheric boundary layer (ABL) of the concerned region. Based on the
modelling results of WRF-CMAQ (Weather Research and Forecasting and
Community Multiscale Air Quality), the two O3 budgets were applied to
comprehensively understand the effects of transport and photochemistry on
the O3 pollution over the Pearl River Delta (PRD) region in China.
Quantified results demonstrate the different role of transport and
photochemistry when comparing the two O3 budgets: photochemistry drives
the rapid increase of O3 concentrations during the day, whereas
transport, especially vertical exchange through the ABL top, controls both
rapid O3 mass increase in the morning and decrease in the afternoon.
The diurnal changes of the transport contributions in the two O3
budgets highlight the influences of the ABL diurnal cycle and regional wind
fields on regional O3 pollution. Through high contributions to the
O3 mass increase in the morning, transport determines that most O3
in the PRD originates from the global background and emissions outside the
region. However, due to the simultaneous rapid increase of ABL volumes, this
process only has a relatively limited effect on O3 concentration
increase compared to photochemistry, and transport effect on the regional
sources of O3 cannot be illustrated by the O3 concentration
budget. For future studies targeting O3 and other secondary pollutants
with moderately long atmospheric lifetimes (e.g. fine particulate matter
and some of its components), insights from both concentration and mass
budgets are required to fully understand the role of transport, chemistry
and other related processes.
Does prognostic seeding along flight tracks produce the desired effects of cirrus cloud thinning?
Authors: Tully Colin , Neubauer David , Villanueva Diego , Lohmann Ulrike
Published: July 2023

Abstract. To date the climate intervention (CI) proposal of cirrus cloud thinning (CCT) was only assessed in general circulation models (GCMs) using a globally uniform distribution of artificial ice nucleating particles (INPs). In this study, we made the first attempt using the ECHAM–HAM (Hamburg Aerosol Module) GCM to simulate CCT using a fully prognostic cirrus seeding aerosol species. Seeding particles were assumed to be made of bismuth triiodide and were emitted into the atmosphere following aircraft emissions of black carbon (soot). This new approach drastically reduced the number concentration of seeding particles available as INPs in our cirrus ice nucleation sub-model compared to the globally uniform approach. As a result, we found that in order to achieve a significant signal we needed to reduce the assumed radius of emitted seeding particles by an order of magnitude to 0.01 µm and scale the mass emissions of seeding particles by at least a factor of 100 or 1000. This latter scaling factor led to a large net top-of-atmosphere (TOA) warming effect of 5.9 W m−2. This warming effect was a clear response to overseeding with a large concentration of seeding particles (>105 L−1 in the Northern Hemisphere) that was most evident in the tropics. Due to this undesired effect, in a second series of simulations we avoided seeding the tropics by restricting emissions to only the Northern Hemisphere (NH) during winter. We also found a small and insignificant effect, or overseeding, which for the extreme case was reduced compared to the global aircraft emission scenario (2.2 W m−2). Ice crystal radius anomalies were not what we expected, with the largest reduction in size found for the case with a mass scaling factor of 10 instead of the extreme, ×1000, scenario. We attributed this peculiar behavior to the differences in the competition between different seeding particle concentrations and background particles. Finally, we also found that seeding with such large concentrations increased the albedo effect of mixed-phase clouds in the NH due to less efficient cloud droplet consumption, consistent with previous findings from our model. Overall, however, based on this study it is recommended to pause further modeling efforts of CCT unless more observational-based evidence of aerosol–ice-cloud interactions indicates favorable conditions for producing the desired outcome of this CI proposal.
Estimating the seasonal impact of optically significant water constituents on surface heating rates in the western Baltic Sea
Authors: Cahill Bronwyn E. , Kowalczuk Piotr , Kritten Lena , Gräwe Ulf , Wilkin John , Fischer Jürgen
Published: July 2023

Abstract. Heating rates induced by optically significant water constituents
(OSCs), e.g. phytoplankton and coloured dissolved organic matter (CDOM),
contribute to the seasonal modulation of thermal energy fluxes across the
ocean–atmosphere interface in coastal and regional shelf seas. This is
investigated in the western Baltic Sea, a marginal sea characterised by
considerable inputs of freshwater carrying nutrients and CDOM and by complex
bio-optical and hydrodynamic processes. Using a coupled bio-optical ocean
model (ROMS–Bio-Optic), the inherent optical properties of different OSCs
are modelled under varying environmental conditions, and the underwater light
field is spectrally resolved in a dynamic ocean. We estimate the relative
contribution of these OSCs to the divergence of the heat flux and heating
rates and find that, while phytoplankton and CDOM both contribute to surface
heating in summer, phytoplankton dominates the OSC contribution to heating
in spring, and CDOM dominates the OSC contribution to heating in autumn. The
study shows that seasonal and spatial changes in OSCs in the western Baltic
Sea have a small but noticeable impact on radiative heating in surface
waters and consequences for the exchange of energy fluxes across the air–sea
interface and the distribution of heat within the water column. In the
Pomeranian Bight, where riverine influx of CDOM is strongest, water-constituent-induced heating rates in surface waters in 2018 are estimated to
be between 0.8 and 0.9 K m−1 d−1 in spring and summer,
predominantly as a result of increased absorption by phytoplankton and CDOM.
Further offshore, OSC-induced heating rates during the same periods are
estimated to be between 0.4 and 0.8 K m−1 d−1. Warmer surface
waters are balanced by cooler subsurface waters. Surface heat fluxes
(latent, sensible and longwave) respond to warmer sea surface temperatures,
with a small increase in heat loss to the atmosphere of 5 W m−2 during
the period April to September. We find relatively good agreement between our
modelled water constituent absorption and in situ and satellite
observations. More rigorous co-located heating-rate calculations using an
atmosphere–ocean radiative transfer model provide evidence of the
suitability of the ROMS–Bio-Optic model for estimating heating rates.
Past and future of the Arctic sea ice in HighResMIP climate models
Authors: Selivanova Julia , Iovino Doroteaciro , Cocetta Francesco
Published: July 2023

Abstract. We examine the past and projected changes in Arctic sea ice properties in 6 climate models participating in the High Resolution Model Intercomparison Project (HighResMIP) in the Coupled Model Intercomparison Project Phase 6 (CMIP6). Within HighResMIP each of the experiments are run using a reference resolution configuration (consistent with typical CMIP6 runs) and higher resolution configurations. The role of horizontal grid resolution in both the atmosphere and ocean model components in reproducing past and future changes in the Arctic sea ice cover is analysed. Model outputs from the coupled historical (hist-1950) and future (highres-future) runs are used to describe the multi-model, multi-resolution representation of the Arctic sea ice and to evaluate the systematic differences (if any) that resolution enhancement causes. Our results indicate that there is not a strong relationship between the representation of sea ice cover and the ocean/atmosphere grid: the impact of horizontal resolution depends rather on the examined sea ice characteristic and the model used. However, the refinement of the ocean grid has a more prominent effect compared to the atmosphere: eddy-permitting ocean configurations provide more realistic representations of sea ice area and sea ice edge. All models project substantial sea ice shrinking: the Arctic loses nearly 95 % of sea ice volume from 1950 to 2050. The model selection based on historical performance potentially improves the accuracy of the model projections and predicts the Arctic to turn ice-free as early as in 2047. Along with the overall sea ice loss, changes in the spatial structure of the total sea ice and its partition in ice classes are noticed: the marginal ice zone (MIZ) dominates the ice cover by 2050 suggesting a shift to a new sea ice regime much closer to the current Antarctic sea ice conditions. The MIZ-dominated Arctic might drive developments and modifications of model physics and parameterizations in the new generation of GCMs.
The role of a low-level jet for stirring the stable atmospheric surface layer in the Arctic
Authors: Egerer Ulrike , Siebert Holger , Hellmuth Olaf , Sorensen Lise Lotte
Published: July 2023

Abstract. In this study, we analyze the transition of a stable atmospheric boundary layer (ABL) with a low-level jet (LLJ) to a traditional stable ABL with a classic Ekman helix in the late-winter central Arctic. Vertical profiles in the ABL were measured with a hot-wire anemometer on a tethered balloon during a 15 h period in March 2018 in northeast Greenland. The tethered balloon allows high-resolution turbulence observations from the ground to the top of the ABL. The core of the LLJ was observed at about 150 m altitude, and its height and strength were associated with the temperature inversion. Increased turbulence was observed in the vicinity of the LLJ, but most of the turbulence does not reach down to the surface, thus decoupling the LLJ from the surface. Only when the LLJ collapses and the ABL again exhibits a more classical Ekman spiral, a coupling to the surface is re-established. Numerical simulations using an analytical model support these observations and allow conclusions to be drawn about the possible role of an LLJ in the advection of a passive tracer such as aerosol particles or moisture.
German Theoryals Geographie im Konjunktiv, oder: „Was nie geschrieben wurde, lesen“
Authors: Korf Benedikt
Published: July 2023

Abstract. „German Theory“ is a theory that has not yet been written, but could have been. „Theory“ is here understood as a “territory of thought” that transcends the boundaries of its origins, and travels to other sites. „French Theory“, for example, is the label for the travel of French poststructuralism to Anglophone humanities. In this sense, „German Theory“ does not exist (yet), but as this paper will argue, it exists as a potentiality that has not (yet) actualized. To show this potential, this paper turns to the work of Friedrich A. Kittler. To illustrate why Kittler did not become a cornerstone of „German Theory“, and to discuss how it could have been, this paper proceeds in two steps: first, it traces the recent history of the reception of Foucault in German language geography and the humanities. This analysis shows that Kittler and German language geography morphed Foucault's discourse theory into two distinct thought styles – the „discourse school“ in German language geography into a „textual“ one; Kittler into a „materialist“ one. This incompatibility of thought styles, this paper asserts, obstructed the travel of Kittler to Anglophone geography, although Kittler's notion of „materiality of communication“ resonates with the „material turn“ in Anglophone geography. Nor did the Foucault of the „discourse school“ travel to Anglophone geography. Kittler's „German Foucault“ travelled to Anglophone media studies as „German School“, though. In the last part of the paper, I ask the question how Kittler's „German Foucault“ could have travelled to (anglophone) geography and what could have been gained theoretically through this travel.
Making geoscientific lab data FAIR: A conceptual model for a geophysical laboratory database
Authors: Nordsiek Sven , Halisch Matthias
Published: July 2023

Abstract. The term of geoscientific laboratory measurements involves a variety of methods in geosciences. Accordingly, the resulting data comprise many different data types, formats, and sizes, respectively. Handling such a diversity of data, e.g., by storing the data in a generally applicable database, is difficult. Some discipline-specific approaches exist, but a geoscientific laboratory database that is generally applicable to different geoscientific disciplines is missing up to now. However, making research data available to scientists beyond a particular community has become increasingly important. Within a pilot project of the NFDI4Earth initiative, we developed a conceptual model for a geoscientific laboratory database. For being able to handle complex settings of geoscientific laboratory studies, flexibility and extensibility are key attributes of the presented approach. The model is intended to follow the FAIR data principles to facilitate interdisciplinary applicability. In this study, we consider different procedures from existing database models and include these methods in the conceptual model.
Evaluation of snow depth retrievals from ICESat-2 using airborne laser-scanning data
Authors: Deschamps-Berger César , Gascoin Simon , Shean David , Besso Hannah , Guiot Ambroise , López-Moreno Juan Ignacio
Published: July 2023

Abstract. The unprecedented precision of satellite laser altimetry data from the NASA ICESat-2 mission and the increasing availability of high-resolution
elevation datasets open new opportunities to measure snow depth in mountains, a critical variable for ecosystem and water resource monitoring. We
retrieved snow depth over the upper Tuolumne basin (California, USA) for 3 years by differencing ICESat-2 ATL06 snow-on elevations and various
snow-off digital elevation models. Snow depth derived from ATL06 data only (snow-on and snow-off) offers a poor temporal and spatial coverage,
limiting its potential utility. However, using a digital terrain model from airborne lidar surveys as the snow-off elevation source yielded a snow depth
accuracy of ∼ 0.2 m (bias) and precision of ∼ 1 m (random error) across the basin, with an improved precision
of 0.5 m for low slopes (< 10∘), compared to eight reference airborne lidar snow depth maps. Snow depths derived from ICESat-2
ATL06 and a satellite photogrammetry digital elevation model have a larger bias and reduced precision, partly induced by increased errors in
forested areas. These various combinations of repeated ICESat-2 snow surface elevation measurements with satellite or airborne products will enable
tailored approaches to map snow depth and estimate water resource availability in mountainous areas with limited snow depth observations.
ОСНОВНІ НАПРЯМИ УДОСКОНАЛЕННЯ ВИКЛАДАННЯ НАВЧАЛЬНОЇ ДИСЦИПЛІНИ «СПАДКОВЕ ПРАВО»
Authors: Кухарєв Олександр Євгенович
Published: July 2023

Стаття присвячена удосконаленню викладання навчальної дисципліни «Спадкове право». У роботі окреслено та проаналізовано два напрями удосконалення викладання цієї дисципліни. Методологічний напрям зумовлений особливостями спадкового права як елемента системи приватного права та визначає засади, на яких має ґрунтуватися викладання відповідної навчальної дисципліни: а) спадкове право за своїм призначенням у системі цивільно-правових норм, а також за обсягом правового матеріалу виходить за межі звичайних уявлень про правовий інститут і фактично є підгалуззю цивільного права; б) пріоритет спадкування за заповітом над спадкуванням за законом: воля особи тут первинна, а роль заповіту зводиться до рангу регулятора цивільних правовідносин, який по суті замінює закон; в) спадковий договір не регулює спадкових правовідносин, є договором на випадок смерті, а не договором про спадкування. Норми глави 90 Цивільного кодексу України складають інститут зобов’язального, а не спадкового права. Через це спадковий договір недоцільно вивчати в межах курсу «Спадкове право». Практичний напрям пов’язаний з освітнім процесом з огляду на його практичну спрямованість. Проблему істотного розриву між юридичною освітою і правозастосовною діяльністю пропонується розв’язувати шляхом застосування таких засобів забезпечення практикоорієнтованості викладання навчальної дисципліни «Спадкове право»: а) впровадження кейс- методу навчання; б) створення на базі закладів вищої освіти юридичних клінік та активне залучення здобувачів вищої освіти до їх роботи; в) долучення до навчального процесу представників правничих спільнот у формі проведення бінарних занять.
ПРОБЛЕМАТИКА РЕГАЛМЕНТАЦІЇ СТРОКІВ ДОСУДОВОГО РОЗСЛІДУВАННЯ У КРИМІНАЛЬНООМУ ПРОВАДЖЕННІ ПІСЛЯ ПОВЕРНЕННЯ ОБВИНУВАЛЬНОГО АКТУ ПРОКУРОРУ
Authors: Говорун Євгенія Олексіївна
Published: July 2023

Стаття присвячена дослідженню строків досудового розслідування у кримінальному провадженні після повернення обвинувального акту прокурору. Проведення слідчих (розшукових) дії поза межами строків досудового розслідування тягне визнання таких доказів недопустимими. Водночас, відповідно до ч. 1 ст. 28 КПК України під час кримінального провадження кожна процесуальна дія або процесуальне рішення повинні бути виконані або прийняті в розумні строки. Неоднозначність регламентації та обчислення строків досудового розслідування після повернення обвинувального акту прокурору в умовах формування військового стану є, на сьогодні, найбільш актуальними для наукового дослідження. Проблематика регламентації строків досудового розслідування у кримінальному провадженні після повернення обвинувального акту прокурору, знаходиться у площині цілого ряду законодавчо невизначених питань, щодо яких також немає єдності думок серед науковців. Однозначно, обвинувальний акт, який підписується і затверджується прокурором, повинен відповідати вимогам ст. 291 КПК України, зокрема із повними даними щодо особи обвинуваченого. Тому, що відсутність в обвинувальному акті таких відомостей унеможливлює якісно і в повній мірі здійснювати розгляд кримінального провадження судом та є підставою для повернення обвинувального акта. Та вже відомо, що проведення будь- яких процесуальних дій, крім тих, що зазначені в ухвалі про повернення обвинувального акта, клопотання про застосування примусових заходів медичного або виховного характеру, не допускається. Крім того, на підставі аналізу судової практики, яка регулює порядок обчислення строків досудового розслідування констатовано, що вітчизняне кримінальне процесуальне законодавство у розрізі теми дослідження потребує докорінної модернізації. Зокрема, запропоновано внести зміни до п. 3 ч. 3 ст. 314 та ст. 219 КПК України доповнивши законодавство конкретними строками для усунення недоліків, виявлених судами в обвинувальних актах та зрозумілим порядком обчислень строків досудового розслідування вцілому.
O software julgador da inteligência artificial: A crítica hermenêutica da discricionariedade em tempos de idolatria à técnica
Authors: Lopes Saldanha Jânia Maria , dos Santos Witschoreck Pedro Victor
Published: July 2023

The research addressed the idea of judgmental software, as a replacement for human judgements, through a hermeneutic critique approach. For this purpose, it dealt with issues involving discretion in the context of the network society and the influence of technology. The investigated problem relates to possibilities of legal hermeneutics regarding the validity of a decision taken by the judgmental software, mediated by artificial intelligence (AI) and considering the way in which the technique takes place in the network society. For the development, it investigated the judging in the hyperconnected society and the intersections of the technology upon it, taking into account Information and Communication Technologies. The research studied artificial intelligence and the relationship between discretion and technology in the construction of judging software through a hermeneutic-legal perspective. The research adopted a hermeneutic-phenomenological approach, investigating AI and the facticity of the lifeworld in the face of the network society. With this, it sought to formulate understandings for the legal validity of the decisions of the judging software. Thus, a relationship was made with discretion, emanating from the paradigm of the philosophy of consciousness, and the influence of technique. The conclusion is that the validity of the decision comes from the impossibility of the judge to act in a discretionary way, away from the chain romance that consists of the law. Therefore, the decision rendered by the judging software is devoid of validity since the correct response is not predetermined.
Benchmarking Australian Enabling Programs for a National Framework of Standards
Authors: Davis Charmaine , Cook Chris , Syme Suzi , Dempster Sarah , Duffy Lisa , Hattam Sarah , Lambrinidis George , Lawson Kathy , Levy Stuart
Published: July 2023

Enabling education programs in Australia assist students, who would otherwise have been excluded from higher education, to transition into undergraduate study. These programs emerged independently in response to the needs of individual universities and the varying cohorts of students they serve. The exclusion of these programs from the Australian Qualifications Framework (AQF) has meant they remain unregulated, with no national framework for standards. The development of academic standards is a dynamic, consensus driven process, and benchmarking provides a method through which academics from across institutions can work in partnership to reach shared understandings and improve and align practices. This practice report outlines the results of the first comprehensive cross-institutional benchmarking project involving nine Australian universities and demonstrates there is shared understanding of the standards of enabling programs between institutions. These findings will contribute to the establishment of national standards for enabling programs in Australia.
Delivering Resilience: Embedding a Resilience Building Module into First-Year Curriculum
Authors: Goodchild Tracy , Heath Georgina , Richardson Amanda
Published: July 2023

Starting university is challenging. Students require resilience to face the inevitable challenges of university life, yet many may not be equipped with the strategies they need. In this research, we explored changes in resilience following the delivery of a resilience building module within a core first-year university course. Psychology students at the University of South Australia completed the adapted Resilience at Work Scale at two separate time points and undertook a resilience building module. Pre- and post-scores were obtained for students’ resilience (n = 205; n = 100 respectively); overall and components. On average, students had good levels of resilience at commencement, yet scores increased significantly across most components following completion of the module. Additionally, students who reported implementing resilience strategies experienced significantly higher score increases than their peers who did not. These findings hold important implications for staff across universities in relation to embedding resilience building programs into curriculum.
Anterior Cruciate Ligament Reconstruction and Accelerated Rehabilitation with InternalBrace™ Augmentation in a Professional Footballer
Authors:   ScribePro, Glasgow, United Kingdom, Stokes Adam , Tompos Tony ,   Scottish Rugby Union, Edinburgh, United Kingdom, Hopper Graeme P. ,   NHS Lanarkshire University Hospitals, Scotland, United Kingdom, Wilson William T. ,   Department of Biomedical Engineering, University of Strathclyde, Glasgow, Scotland, Mackay Gordon M. ,   University of Stirling, Scotland, United Kingdom
Published: July 2023

Introduction: Interest in anterior cruciate ligament (ACL) repair has been increasing as an alternative to traditional reconstructive techniques and encouraging results have been demonstrated using internal bracing with suture tape augmentation (FiberTape®, Arthrex, Naples, Florida). ACL repair is challenging if the rupture is mid-substance or distal. We describe the case of a hybrid ACL reconstruction with internal brace augmentation. Materials and Methods: This retrospective case report documents the rehabilitation process of a 31-year-old professional footballer who had an isolated ACL rupture. The patient underwent a hybrid ACL reconstruction with bone-patellar tendon-bone autograft and suture tape augmentation 10 days after his injury. A task-based rehabilitation programme defined by six progressive phases relevant to performance-based outcome measures was undertaken. Each phase had clear, functional, progressive goals incorporating exercises to improve mobility, neuromuscular control, strength, and a progressive return to running and sport-specific movements. Results: Using the rehabilitation framework outlined, this player produced excellent results in all objective criteria postoperatively and was able to return to unrestricted full team training in under five months (146 days) following surgery. Conclusions: This case presentation demonstrates the safe and accelerated return to professional football following ACL reconstruction augmented with internal bracing. The player was able to meet all criteria-based aspects of return to play.
La Búsqueda de Políticas Ambientales para la Actividad Constructora en la Ciudad de Cochabamba
Authors: García Arteaga Gaby
Published: July 2023

La necesidad imperiosa de resolver algunos problemas que conllevan un perjuicio a la calidad de vida de los habitantes de una ciudad, debe responder al postulado que refiere a desplegar diferentes actividades sin comprometer la posibilidad de que las futuras generaciones no puedan disponer de recursos dentro de un determinado territorio, considerando la Huella Ecológica que se podría presentar y que perjudique al buen desenvolvimiento de diversas acciones dentro del ambiente. En este artículo se desarrollaron un conjunto de conceptos y se identificaron problemas así como las estrategias que permitan definir las características de las construcciones para el logro de una mayor sostenibilidad o ecoeficiencia.
Programación Móvil Android con Appinventor en Educación Secundaria
Authors: Escalera Cruz Angel David
Published: July 2023

El campo de la tecnología móvil está empezando a adentrarse en el mundo de la educación, a través de lo que llamamos Mobile Learning o mearning. Existe un servicio web de Google llamado App Inventor que permite a usuarios de cualquier edad desarrollar su propia aplicación Android de una forma visual y muy sencilla. El objetivo es conducir al estudiantado en su propio aprendizaje planteando proyectos con un nivel exigente en cuanto a desarrollo de competencias y uso de las TICs, despertando actitudes de emprendimiento, interés social, económico y cultural sobre nuestro entorno