bluuebunny/crossref_metadata_2025 huggingface dataset:
Homogenized moment tensor and the effect of near‐field heterogeneities on nonisotropic radiation in nuclear explosion
Authors: Burgos Gaël , Capdeville Yann , Guillot Laurent
Published: May 2016

We investigate the effect of small‐scale heterogeneities close to a seismic explosive source, at intermediate periods (20–50 s), with an emphasis on the resulting nonisotropic far‐field radiation. First, using a direct numerical approach, we show that small‐scale elastic heterogeneities located in the near‐field of an explosive source, generate unexpected phases (i.e., long period S waves). We then demonstrate that the nonperiodic homogenization theory applied to 2‐D and 3‐D elastic models, with various pattern of small‐scale heterogeneities near the source, leads to accurate waveforms at a reduced computational cost compared to direct modeling. Further, it gives an interpretation of how nearby small‐scale features interact with the source at low frequencies, through an explicit correction to the seismic moment tensor. In 2‐D simulations, we find a deviatoric contribution to the moment tensor, as high as 21% for near‐source heterogeneities showing a 25% contrast of elastic values (relative to a homogeneous background medium). In 3‐D this nonisotropic contribution reaches 27%. Second, we analyze intermediate‐periods regional seismic waveforms associated with some underground nuclear explosions conducted at the Nevada National Security Site and invert for the full moment tensor, in order to quantify the relative contribution of the isotropic and deviatoric components of the tensor. The average value of the deviatoric part is about 35%. We conclude that the interactions between an explosive source and small‐scale local heterogeneities of moderate amplitude may lead to a deviatoric contribution to the seismic moment, close to what is observed using regional data from nuclear test explosions.
Adaptive control for a class of uncertain linear parameter‐varying flight aircraft systems
Authors: Liu Chun‐sheng , Ye Qing , Zhang Shao‐jie
Published: May 2016

The concept of linear parameter‐varying (LPV) model has been developed as a convenient framework to describe a special class of uncertain LPV flight aircraft systems. In this paper, an adaptive control method for a class of uncertain LPV systems whose state‐space matrix elements are unknown affine functions of a set of measurable scalar parameters is presented. Firstly, the scalar parameters are separated from the state matrices such that the LPV model is rewritten as general unknown parameter model, then state feedback adaptive control laws, in both cases: the matched uncertainty and the unmatched uncertainty, are designed with the aim of controlling the system state to follow a desired trajectory. The sufficient condition of stability is derived using a Lyapunov equation, not a parameterized Lyapunov equation. Simulation tests based on a simple example and a nonlinear model of a transport aircraft are given to illustrate the effectiveness of the control algorithm and to demonstrate that the adaptive controller satisfies the performance requirement for an aircraft control system. Copyright © 2016 John Wiley & Sons, Ltd.
In‐Plane Self‐Turning and Twin Dynamics Renders Large Stretchability to Mono‐Like Zigzag Silicon Nanowire Springs
Authors: Xue Zhaoguo , Xu Mingkun , Li Xing , Wang Jimmy , Jiang Xiaofan , Wei Xianlong , Yu Linwei , Chen Qing , Wang Junzhuan , Xu Jun , Shi Yi , Chen Kunji , Roca i Cabarrocas Pere
Published: May 2016

Crystalline Si nanowire (SiNW) springs, produced via a low temperature (<350 °C) thin film technology, are ideal building blocks for stretchable electronics. Herein, a novel cyclic crystallographic‐index‐lowering self‐turning and twin dynamics is reported, during a tin‐catalyzed in‐plane growth of SiNWs, which results in a periodic zigzag SiNW without any external parametric intervention. More interestingly, a unique twin‐reflected interlaced crystal‐domain structure has been identified for the first time, while in situ and real‐time scanning electron microscopy observations reveal a new twin‐triggering growth mechanism that is the key to reset a complete zigzag growth cycle. Direct “stress–strain” testing of the SiNW springs demonstrates a large stretchability of 12% under tensile loading, indicating a whole new strategy and capability to engineer mono‐like SiNW channels for high performance stretchable electronics.
Palladium‐Catalyzed One‐Pot Synthesis of 5‐(1‐Arylvinyl)‐1H‐benzimidazoles: Overcoming the Limitation of Acetamide Partners
Authors: Naret Timothée , Retailleau Pascal , Bignon Jérôme , Brion Jean‐Daniel , Alami Mouad , Hamze Abdallah
Published: May 2016

A new one‐pot palladium‐catalyzed process between N‐tosylhydrazones, N‐(dihalophenyl)‐imidates, and amines was designed. This reaction involves Barluenga cross‐coupling and N‐arylation followed by cyclization to produce functionalized benzimidazoles. During this transformation, one CC bond and two CN bonds were created by a single palladium‐catalyzed reaction. Depending on the starting materials, a library of 5‐(1‐arylvinyl)‐1H‐benzimidazoles was synthesized. Among several arylvinylbenzimidazole derivatives evaluated, one compound exhibits excellent antiproliferative activity in the nanomolar concentration range against human colon carcinoma cell lines (HCT‐116) and human lung adenocarcinoma epithelial cell lines (A549).

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Chemophototherapy: An Emerging Treatment Option for Solid Tumors
Authors: Luo Dandan , Carter Kevin A. , Miranda Dyego , Lovell Jonathan F.
Published: May 2016

Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a method to safely deliver non‐ionizing radiation to well‐defined target tissue volumes. Light‐based therapies including photodynamic therapy (PDT) and laser‐induced thermal therapy have been validated clinically for curative and palliative treatment of solid tumors. However, these monotherapies can suffer from incomplete tumor killing and have not displaced existing ablative modalities. The combination of phototherapy and chemotherapy (chemophototherapy, CPT), when carefully planned, has been shown to be an effective tumor treatment option preclinically and clinically. Chemotherapy can enhance the efficacy of PDT by targeting surviving cancer cells or by inhibiting regrowth of damaged tumor blood vessels. Alternatively, PDT‐mediated vascular permeabilization has been shown to enhance the deposition of nanoparticulate drugs into tumors for enhanced accumulation and efficacy. Integrated nanoparticles have been reported that combine photosensitizers and drugs into a single agent. More recently, light‐activated nanoparticles have been developed that release their payload in response to light irradiation to achieve improved drug bioavailability with superior efficacy. CPT can potently eradicate tumors with precise spatial control, and further clinical testing is warranted.
Superstructure optimization of integrated fast pyrolysis‐gasification for production of liquid fuels and propylene
Authors: Yuan Zhihong , Eden Mario R.
Published: May 2016

Motivated by the apparent advantages of fast pyrolysis and gasification, a novel integrated biorefinery plant is systematically synthesized for coproducing premium quality liquid fuels and propylene. The required heat and fluidization promotion of the fast pyrolyzer are provided by hot syngas from the gasifier. Light gas and syngas from the fast pyrolyzer are finally converted to hydrocarbons via Fischer‐Tropsch synthesis. Multiple syngas production technologies, hydrocarbon production and downstream upgrading routes are incorporated within a superstructure optimization based process synthesis framework. This is the first article to investigate the benefits associated with the introduction of conventional catalytic cracking and dewaxing from a systems engineering perspective. Surrogate models describing the gasifiers and rigorous equations for Fischer‐Tropsch effluents validated by our experimental collaborator are introduced. Through investigation of five scenarios the primary parameters affecting overall economic performance are identified through ranking of the relevant candidates. Comparisons of the hybrid conversion route and stand‐alone routes are made. © 2016 American Institute of Chemical Engineers AIChE J, 62: 3155–3176, 2016
A phase 2, multicenter study investigating ofatumumab and bendamustine combination in patients with untreated or relapsed CLL
Authors: Flinn Ian W. , Panayiotidis Panayiotis , Afanasyev Boris , Janssens Ann , Grosicki Sebastian , Homenda Wojciech , Smolej Lukas , Kuliczkowski Kazimierz , Doubek Michael , Domnikova Natalia , West Sarah L. , Chang Chai‐Ni , Barker Alison M. , Gupta Ira V. , Wright Oliver J. , Offner Fritz
Published: May 2016

The purpose of this study is to assess the safety and efficacy of the combination of ofatumumab and bendamustine in patients with previously untreated or relapsed chronic lymphocytic leukemia. Patients received IV ofatumumab (cycle 1: 300 mg day 1 and 1,000 mg day 8; cycles 2–6: 1,000 mg on day 1 every 28 days) and IV bendamustine 90 mg m−2 (previously untreated) or 70 mg m−2 (relapsed) on days 1 and 2 of each 28‐day cycle, for up to 6 cycles. Forty‐four previously untreated and 53 relapsed patients were enrolled. Median age was 62.5 years (previously untreated) and 68 years (relapsed); relapsed patients had received a median of 1 (range 1–11) prior therapy. The investigator‐assessed overall response rate was 95% (43% complete response [CR]) for the previously untreated, and 74% (11% CR) for the relapsed patients. The regimen was well tolerated with 89% (previously untreated) and 85% (relapsed patients) receiving all 6 cycles. No unexpected toxicities were reported. Grade 3/4 events occurred in 57% of previously untreated, and 72% of relapsed patients. At ∼29 months’ follow‐up, the median progression‐free survival (PFS) was not reached for the previously untreated population, and the 28‐month PFS estimate was 72.3%. The median PFS for the relapsed population was 22.5 months (95% CI: 14.0–27.3 months). The combination of ofatumumab and bendamustine was well tolerated and effective in these previously untreated or relapsed populations. Am. J. Hematol. 91:900–906, 2016. © 2016 Wiley Periodicals, Inc.
N‐Alkyl Ammonium Resorcinarene Chloride Receptors for Guest Binding in Aqueous Environment
Authors: Beyeh Ngong Kodiah , Pan Fangfang , Ras Robin H. A.
Published: May 2016

Host systems with guest binding ability in water and/or biological fluids are a current challenge in supramolecular host–guest chemistry. Here we present the first syntheses of water‐soluble N‐ethanol ammonium resorcinarene chlorides (NARCls) with terminal hydroxyl groups at the upper rim. The NARCls possess deep cavities and are shown to bind a variety of guest molecules such as linear and cyclic alkanes, linear halogenated alkanes, and aromatic fluorophores (naphthalene, p‐(phenylazo)phenol) in water through hydrophobic interactions, as well as 1,4‐dioxane (a water soluble guest) via hydrogen bonds. The receptors are monomeric in aqueous media and form 1:1 host–guest complexes with binding constants of up to 559 m−1 in D2O/MeOD (9:1, v/v) at 298 K. Solid‐state analysis in purely organic media, reveals a dimeric 2:2 capsule and a self‐included dimer of nanometer dimensions. The host–guest complexes are analyzed in solid state by single‐crystal X‐ray diffraction and in solution by 1H NMR and diffusion‐ordered NMR spectroscopy.
Orexins and receptor OX2R in the gastroenteric apparatus of two teleostean species: Dicentrarchus labrax and Carassius auratus
Authors: D'Angelo Livia , Castaldo Luciana , de Girolamo Paolo , Lucini Carla , Paolucci Marina , Pelagalli Alessandra , Varricchio Ettore , Arcamone Nadia
Published: May 2016

Orexin A and B peptides and the receptor OX2R were studied in sea bass and goldfish gastroenteric tract by immunoblotting combined with densitometric analysis using NIH Image J software and immunohistochemical techniques. These teleost species present a different gut organization and diverse feeding habits. Immunoblotting experiments showed one band of 16 kDa corresponding to prepro‐orexin, and one band of 38 kDa corresponding to the OX2R receptor. Immunohistochemical localization of OXA and OXB was observed in the enteric nervous system throughout the gastroenteric tract of both species. OXA and OXB immunoreactive cells were found in the gastric and intestinal regions of sea bass, and were mainly found in the basal region of folds in intestinal bulb, and in the midgut and hindgut of goldfish. The distribution of OX2R was mainly detected in the mucosa of the gastroenteric tract of sea bass and goldfish. This distribution suggests an endocrine action of OXA and OXB in the gastrointestinal tract as well as involvement in the peripheral control of food intake and digestive processes in both species. This study might also serve to determine the productive factors in breeding and as a baseline for future experimental studies on the regulation of the gastroenteric functions in non‐mammalian vertebrates. Anat Rec, 299:1121–1129, 2016. © 2016 Wiley Periodicals, Inc.
Empower, Account, Integrate and Sustain: The Board Administrator's Role
Authors: Halsted Julia Steiner
Published: May 2016

Rockford Park District in Illinois (United States) operates 177 parks and facilities. As a major part of her role as Policy Governance and Community Relations Manager for the District, Julia Steiner Halsted is responsible for the administration of its use of the Policy Governance® system. Here, she reflects on what she has learned.
Simultaneous determination of ginsenoside Rg1, Re and notoginsenoside R1 in human plasma by LC‐MS/MS and its application in a pharmacokinetic study in Chinese volunteers
Authors: Zhang Xiqian , Ma Rujun , Liu Xiaojuan , Jiang Xuehua , Wang Ling
Published: May 2016

A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method has been developed and validated for simultaneous quantification of ginsenosides Rg1, Re and notoginsenoside R1 in human plasma. Chromatography was performed on Capcell Pak C18 MG II column using a binary gradient using mobile phase A (5 mm ammonium formate solution) and B (methanol, containing 5 mm ammonium formate) at a flow rate of 0.3 mL/min. The entire chromatographic run time was 3.2 min. Quantification was achieved using multiple reaction monitoring in positive mode using API 3000. This method was validated in terms of specificity, linearity, precision, accuracy, matrix effect and stability. The calibration curves were linear in the concentration range of 0.020–5.00 ng/mL for ginsenosides Rg1, Re and notoginsenoside R1. The lower limit of quantification (LLOQ) of this method was 0.020 ng/mL. The intra‐run and inter‐run precision values were within 12.31% for ginsenoside Rg1, 14.13% for ginsenoside Re and 11.46% for notoginsenoside R1 at their LLOQ levels. The samples were stable under all tested conditions. This method was successfully applied to study the pharmacokinetics of ginsenoside Rg1 and notoginsenoside R1 in 24 healthy volunteers following oral administration of 200 mg Sanqi Tongshu Enteric‐Pellets Capsule.
Keep your eye on…
Authors: Knopf Alison
Published: May 2016

The need to follow Cushing syndrome patients after remission

The link between heavy teen male marijuana use and increased risk of early death
ChemInform Abstract: Intraframework Potential Energy Function of Zeolites. Molecular Mechanical Studies of the Structure Determination of CsxNa12‐x‐A Type Zeolite and the Transmission of H2 Molecules.
Authors: NO K. T. , KIM J. S. , JHON M. S.
Published: May 2016

Potential energy functions, suitable for the (Cs1‐xNaxT2O4)‐A type zeolite family, obtained from the known crystal structure of Cs7Na5‐A zeolite using a constraint method, are shown to be useful for the investigation of other crystal structures in this family which have not been experimentally obtained.
ChemInform Abstract: Cathodic Deposition of CdS on Cd Substrate and Photoelectrochemical Behavior of Cd/CdS Electrode.
Authors: SKOMPSKA M. , JACKOWSKA K.
Published: May 2016

It is shown that it is possible to cathodically deposit a photoactive CdS film on a cadmium rotating disc electrode from an aqueous solution containing CdSO4 and Na2S2O3.
ChemInform Abstract: A Study of Large Frequency Band Dielectric Relaxation in X, Y, and M Type Zeolites Containing Protons.
Authors: CARRU J.‐C. , DELAFOSSE D. , KERMAREC M.
Published: May 2016

The first investigation of the complex permittivity for the title zeolites in the large frequency range of 1‐109 Hz shows the residual cations and the protons (in the form of hydroxyls) to be responsible for the polarization observed in all cases.
ChemInform Abstract: (Et4N)6(Na14Mo24P17O97(OH)31)·xH2O (I), a Cavity Cluster Occupied with Twelve Na+ Ions and One H3PO4 Molecule.
Authors: HAUSHALTER R. C. , LAI F. W.
Published: May 2016

The title compound (I) is prepared by hydrothermal reaction of Na2MoO4, Mo, (Et4N)OH, H3PO4, and H2O (2:1:2:6:100; 200 °C, 3d, 90% yield).
ChemInform Abstract: High Tc Superconductor Fiber YBa2Cu3O7‐δ Synthesized by the Sol‐Gel Process.
Authors: CHOY J. H. , YOO J. S. , KIM B. W. , HONG S. T.
Published: May 2016

A superconducting fiber having superconducting transition temp. (Tc,onset and Tc,offset) of approximately 95 K and 82 K, resp., is prepared starting from a stoichiometric mixture of Y, Ba, and Cu nitrates dissolved in water by adding 1. citric acid and 2. NH4OH (pH 5.8‐6.2), followed by careful heating to 358 K to form a homogeneous colloid.
ChemInform Abstract: The State of Manganese in the Photosynthetic Apparatus. Part 10. Ammonia Binds to the Catalytic Mn of the Oxygen‐Evolving Complex of Photosystem II: Evidence by Electron Spin‐Echo Envelope Modulation Spectroscopy.
Authors: BRITT R. D. , ZIMMERMANN J.‐L. , SAUER K. , KLEIN M. P.
Published: May 2016

A single NH3‐derived ligand binds to the catalytic Mn complex during the S1 → S2 transition of the oxygen evolution S‐state cycle.
ChemInform Abstract: Synthetic Ionophores. Part 8. Transport of Alkaline Earth Metal Ions by Polyether Carboxylic Acids Through Liquid Membrane.
Authors: YAMAGUCHI K. , KUBONIWA H. , MURAKAMI N. , HIRAO A. , NAKAHAMA S. , YAMAZAKI N.
Published: May 2016

Ionophores such as (I)‐(III) are employed as carriers for active transport of alkali metal ions M+ and especially alkaline earth metal ions M2+ through 1,2‐dichloroethane or hexanol.
ChemInform Abstract: Electrochemical Transformation of Ethylene Ketals to Dimethyl Ketals.
Authors: GORA J. , SMIGIELSKI K. , KULA J.
Published: May 2016

The electrochemical transacetalization of ethylene acetals such as (I) (6 examples) takes place on a platinum or graphite anode.
ChemInform Abstract: Stereospecificity in the Geminate Recombination of 1,3‐Diphenylpropyl Radical Pairs.
Authors: SERELIS A. K. , SOLOMON D. H. , STEEL P. J.
Published: May 2016

The thermolysis of both meso‐ and rac.‐azopropanes (I) is examined (synthesis and thermolysis described in an accompanying paper) with respect to its diastereospecificity without and with addition of nitroxyl radical scavengers.
ChemInform Abstract: The Effect of Pressure on Sigmatropic Rearrangements of Seven‐Membered Conjugated Systems. (3,3) and (1,9) Sigmatropies.
Authors: SUGIYAMA S. , MORI A. , KATO N. , TAKESHITA H.
Published: May 2016

Based on temp., pressure, and solvent effects it is proved that the rearrangement (I) → (II) is undoubtedly a concerted (1,9) sigmatropy.
ChemInform Abstract: Photooxidation of 2‐Phenylbenzotriazoles.
Authors: AMIET R. G. , EVANS N. A. , WYNNE P. M.
Published: May 2016

UV irradiation of (I) under aerobic conditions yields (III) (isolated as diester (V)), presumably via the known quinone (II) (independently prepared from (I) and acidic dichromate; yield 8%).
ChemInform Abstract: Kinetics and Mechanism of the Reaction of Sodium Hydroxide on 4‐Halomethyl‐3‐nitrobenzoic Acids and the Corresponding Non‐Nitro Derivatives in Aqueous Dioxane.
Authors: RIAD Y. , EL‐BARDAN A. , GUNDERMANN K.‐D.
Published: May 2016

The dehalogenation of (Ia) and (IVa) leads to the corresponding dibenzyl ethers and benzyl alcohols.
ChemInform Abstract: Photochemical Synthesis of Fluoroalkanols Based on Tetrafluoroethylen.
Authors: PALETA O. , DEDEK V. , REUTSCHEK H. , TIMPE H.‐J.
Published: May 2016

Reaction of methanol (IIa), ethanol (IIb), and 2‐propanol (IIc) with tetrafluoroethene (I) in the presence of dibenzoyl peroxide is activated by UV‐irradiation to give a mixture of the 1:1‐ (III) and 1:2‐adducts (IV).
ChemInform Abstract: Synthesis of Alkyl Perfluoroalkyl Ketones. Reactions of Allyl Perfluoroalkanoates with Acyl Chlorides in the Presence of Palladium(0).
Authors: CHEN Q.‐Y. , CHEN J.‐G.
Published: May 2016

Reaction of fluoro carbanions, generated by palladium(0)‐induced decomposition of the allyl esters (I), with the acyl chlorides (II) results in the formation of the enol esters (III) and the ketones (IV), (VI), and (VII).
ChemInform Abstract: Cyclohexane‐Based 1,3‐Dipodands: Complexation and Conformational Biasing.
Authors: SHIRODKAR S. M. , WEISMAN G. R.
Published: May 2016

The dipodands (III) are prepared by reaction of the diols (I) with the tosylate (II).
ChemInform Abstract: Synthesis and Properties of the Tridecafulvene Derivatives. The Substituent Effect at the 14‐Position on the Tropicity of Thirteen‐Membered Fulvene System.
Authors: OJIMA J. , MASUMOTO M. , KATSUYAMA J. , KITAMURA K. , IYODA M.
Published: May 2016

Starting with the annulenone (I), the dinitrile (IIIa) is prepared and converted into a series of derivatives such as (IIIb) by standard methods.
ChemInform Abstract: Stereospecific Preparation of Chiral 1,5‐Diketone by One‐Methylene Incorporated Dimerization Reaction of d‐Camphor Enolate and Reduction of the 1,5‐Diketone.
Authors: KIYOOKA S. , YAMASHITA T. , YAMAMOTO A. , FUJIYAMA R.
Published: May 2016

The stereoselective condensation reaction shown in the scheme is proposed to proceed by an attack of d‐camphor enolate to DMF (II) and a subsequent reduction.
ChemInform Abstract: Novel Electrophilic Species Equivalent to α‐Keto Cations. Reactions of O,O‐Diprotonated Nitroolefins with Benzenes Yield Arylmethyl Ketones.
Authors: OKABE K. , OHWADA T. , OHTA T. , SHUDO K.
Published: May 2016

The nitroalkenes (I) are diprotonated with trifluoromethanesulfonic acid, forming the dication salts (II) which are trapped with benzene (III), producing the benzylic ketones (IV).
ChemInform Abstract: Cleavage of Isoxazolines with Tricarbonyltris(acetonitrile)molybdenum and Silica Gel. Synthesis of 1‐(2‐Oxoalkyl)cyclopropanols from Isoxazoline‐5‐spirocyclopropanes.
Authors: GUARNA A. , GUIDI A. , GOTI A. , BRANDI A. , DE SARLO F.
Published: May 2016

The selective cleavage of the N‐O bond in the isoxazoline‐5‐spirocyclopropanes (I) is achieved by consecutive treatment with the molybdenum carbonyl complex mentioned in the title and silica gel, yielding the oxoalkylcyclopropanols (II).
ChemInform Abstract: Metacyclophanes and Related Compounds. Part 21. Nitration of (2.2)Metacyclophanes.
Authors: TASHIRO M. , MATAKA S. , TAKEZAKI Y. , TAKESHITA M. , ARIMURA T. , TSUGE A. , YAMATO T.
Published: May 2016

Nitration of the dimethylmetacyclophane (Ia) using fuming nitric acid (II) or copper nitrate (IV) yields the 5‐nitro derivative (III).
ChemInform Abstract: Rearrangement of a Bicyclic (2.2.2)System to a Bicyclic (3.2.1)System. Nonclassical Ions.
Authors: RACHON J. , GOEDKEN V. , WALBORSKY H. M.
Published: May 2016

The bromobicyclo(2.2.2)octadienecarboxylate (I) undergoes Ag+‐promoted debromination and rearrangement reaction via nonclassical ions to form the hydroxybicyclo(3.2.1)octadienyl system (II) with predominance of the exo‐isomer.
ChemInform Abstract: Regiospecific Syntheses of All Isomeric Nitrofluorenones and Nitrofluorenes by Transition Metal‐Catalyzed Cross‐Coupling Reactions.
Authors: IIHAMA T. , FU J. , BOURGUIGNON M. , SNIECKUS V.
Published: May 2016

The title compounds (VIII) and (X) are prepared as shown in the reaction scheme.
ChemInform Abstract: Reactions of 2,5‐Furandicarbaldehyde with Stabilized Phosphonium Ylides. Applications to the Synthesis of 5‐Vinyl‐2‐furaldehyde and 2,5‐Divinylfuran Derivatives.
Authors: DOMINGUES C. , CSAKY A. G. , MAGANO J. , PLUMET J.
Published: May 2016

2,5‐Furandicarbaldehyde (I) is selectively converted to the 5‐vinyl‐2‐furaldehydes (IV) or the 2,5‐divinylfurans (III) by Wittig reaction with the stabilized ylides (II) in the corresponding stoichiometric ratios.
ChemInform Abstract: Synthesis and Antimicrobial Activities of Some New 1‐Substituted 3‐Methyl‐5‐(2‐naphthyl)‐4‐(p‐(substituted sulfamyl)benzeneazo)pyrazoles.
Authors: AHLUWALIA V. K. , SHARMA H. R. , TYAGI R.
Published: May 2016

The title compounds (V) and (VII) are screened for their antibacterial and antifungal activity.
ChemInform Abstract: Synthesis and Characterization of Masked Aminopyrazolecarboxylic Acid Synthons.
Authors: LEE H. H. , CAIN B. F. , DENNY W. A. , BUCKLETON J. S. , CLARK G. R.
Published: May 2016

Oxidation of 3,5‐dimethylpyrazole (I) yields the dicarboxylic acid (II), which is methylated, forming the diester (IV).
ChemInform Abstract: Preparation of 2‐Amino‐6‐nitrobenzothiazole.
Authors: JIRMAN J. , CERMAK J.
Published: May 2016

1‐Acetyl‐3‐phenylthiourea (I) is nitrated and simultaneously cyclized to give 2‐acetylamino‐6‐nitrobenzothiazole (III) which is hydrolyzed, yielding 2‐amino‐6‐nitrobenzothiazole (IV).
ChemInform Abstract: Synthesis of Isoxazoles and Isothiazoles from α‐Oxoketene Dithioacetals.
Authors: DIETER R. K. , CHANG H. J.
Published: May 2016

The α‐oxoketene dithioacetals (I) are transformed into the corresponding oximes (III).
ChemInform Abstract: Synthesis of 1,2,4‐Triazole, 1,2,4‐Triazolo(3,4‐b)(1,3,4)thiadiazole and 1,2,4‐Triazolo(3,4‐b)(1,3,4)thiadiazine Derivatives of Benzotriazole.
Authors: EL‐KHAWASS S. M. , HABIB N. S.
Published: May 2016

The title compounds (VI), (VIII), (XI), (XIV) and the precursors (III), (V), (X) are tested for their antimicrobial activity.
ChemInform Abstract: Synthesis of 5‐Aryl‐3‐carbazolyl‐1,3,4‐oxadiazol‐2(3H)‐one Derivatives and Their Ring Transformation into 4‐Benzamido‐1,2,4‐triazolidine‐3,5‐dione Derivatives.
Authors: MILCENT R. , BARBIER G. , TZIRENSTCHIKOW T. , LEBRETON L.
Published: May 2016

The title compounds, e.g. (III), do not undergo thermal ring transformation to give the products (IV).
ChemInform Abstract: Reactions of 1,1‐Dimethyl‐4‐Substituted Semicarbazides with Phosgene.
Authors: COOLEY J. H. , EVAIN E. J. , WILLETT R. D. , BLANCHETTE J. T.
Published: May 2016

Reaction of the semicarbazide (I) with two equivalents of phosgene (II) yields the triazolinone (III).
ChemInform Abstract: A Novel Synthesis of 3‐Bromo‐1,2,4‐oxadiazoles.
Authors: HUMPHREY G. R. , WRIGHT S. H. B.
Published: May 2016

The title compounds (III) and (V) are obtained together with 5‐10% of 3,4‐dibromo‐1,2,5‐oxadiazole 2‐oxide.
ChemInform Abstract: Reaction of Hydrazidoyl Halides with Thiocyanate Anion: Synthesis of Thiadiazolines and Thiadiazolo(4,5‐a)quinazoline.
Authors: IBRAHIM M. K. A.
Published: May 2016

The reaction between the chlorides (I) or (IV) and KSCN (II) gives the title compounds (III) and (V), respectively (yields not given).
ChemInform Abstract: A Very Efficient, Short Synthesis of 6,7,8,8a‐Tetrahydropyrrolo(1,2‐a)pyrimidines from Imines via 4‐Amino‐1‐azabutadienes.
Authors: BARLUENGA J. , TOMAS M. , JARDON J. , RUBIO E. , GOTOR V.
Published: May 2016

The ketimines (III), derived from 4‐aminobutyraldehyde acetal (II), are converted to the title compounds (V) by consecutive metalation, coupling with the nitriles (IV), and acid‐catalyzed cyclization.
ChemInform Abstract: Synthesis of 2‐Substituted 2‐Azapyracridone Derivatives.
Authors: HUBER I. , FUELOEP F. + , BERNATH G. , HERMECZ J.
Published: May 2016

Cyclocondensation of the piperidiniumcarboxylate (I) with the aminopyridine (II) in polyphosphoric acid yields the 2‐azapyracridone (III).
ChemInform Abstract: Spirocyclization of 1‐(o‐Aminophenyl)cycloalkanols and 1‐(2′‐Amino‐3′‐pyridinyl)cycloalkanols.
Authors: CANONNE P. , BOULANGER R. , CHANTEGREL B.
Published: May 2016

The one‐step spirocyclization of the title compounds (I) opens a route to the benzoxazinones and pyridooxazinones (III), which is more efficient than previously reported routes.
ChemInform Abstract: Chemistry of 1,4‐Oxazines. Part 18. Synthesis of Tricyclic 1,4‐Benzoxazines via Nucleophilic Substitution of Activated Precursors.
Authors: BARTSCH H. , ERKER T. , NEUBAUER G.
Published: May 2016

The activated benzoxazines (I) and (XIII) serve as educts for a series of title compounds.
ChemInform Abstract: Synthesis of 5‐Oxa‐13‐thiaprotoberberine Derivatives.
Authors: SZABO J. , BERNATH G. , SOHAR P.
Published: May 2016

The hydrochloride (I) of 2‐(aminomethyl)‐4,5‐dimethoxythiophenol undergoes ring closure with salicylaldehyde (II) to form the benzothiazine derivative (III).
ChemInform Abstract: Reactions of Protonated 1,3‐Diaza‐4,4‐diphenyl‐2‐(methylthio)butadienes with Isocyanides: Preparation of Imidazole and Triazine Derivatives.
Authors: MOREL G. , MARCHAND E. , FOUCAUD A. , TOUPET L.
Published: May 2016

Coupling of diphenylmethylenimine (II) with isothiocyanates such as (I) yields thiourea derivatives such as (III) which is converted to the salt (V) by S‐alkylation.
ChemInform Abstract: Reaction of Chloro(chloromethyl)dimethylsilane and ‐germane with Group 14 Element Nucleophiles.
Authors: INOUE S. , SATO Y.
Published: May 2016

In order to prepare periodic group 14 element‐element bonded compounds such as (I) containing a chloromethyl substituent the reactions of the title compounds with the nucleophiles LiM2RMe2 are investigated under various conditions (table).
ChemInform Abstract: Formation of Thiocarbonyl Compounds in the Reaction of Ebselen Oxide with Thiols.
Authors: GLASS R. S. , FAROOQUI F. , SABAHI M. , EHLER K. W.
Published: May 2016

During the reaction of ebselen oxide (I) with benzyl sulfide (II), yielding the seleno sulfide (III) and dibenzyl disulfide (IV), a transient blue color of the intermediately formed thiobenzaldehyde is observed.
ChemInform Abstract: A New Barium Tantalum Oxide Fluoride (III).
Authors: AVERDUNK F. , HOPPE R.
Published: May 2016

The title compound (III) crystallizes in the orthorhombic space group CmCm in which Ta has both coordination number eight in the anion (TaF8)3‐ and seven in the anion (TaF6O)3‐.
ChemInform Abstract: Preparation, Solution Dynamics, and X‐Ray Structure of Bis(pentamethylcyclopentadienyl)actinoid Complexes of Chelating Phosphorus Ylides.
Authors: CRAMER R. E. , ROTH S. , EDELMANN F. , BRUCK M. A. , COHN K. C. , GILJE J. W.
Published: May 2016

The reaction of actinoid compounds (I) with (II) produces the thermally stable complexes (III), which contain chelating ylide ligands.
ChemInform Abstract: Synthesis of η6‐Octafluorocyclooctatetraene and η6‐Cyclooctatetraene Complexes of Manganese(I). Molecular Structures of (Mn(η5‐C5R5)(η6‐C8X8)) (R: H, Me, X: F; R: Me, X: H).
Authors: HEMOND R. C. , HUGHES R. P. , RHEINGOLD A. L.
Published: May 2016

The title complexes (III) are prepared as exemplified for (IIIa).
ChemInform Abstract: Ring‐Opening Hydroformylation of α‐Cyclopropylstyrene by HMn(CO)5, and Structure of a Novel Mn2(CO)9(η1‐Aldehyde) Complex.
Authors: BULLOCK R. M. , RAPPOLI B. J. , SAMSEL E. G. , RHEINGOLD A. L.
Published: May 2016

Reaction of the alkene (I) with HMn(CO)5 (II) produces the η1‐aldehyde complex (III) via ring opening and hydroformylation.
ChemInform Abstract: Synthesis of Hybrid “Metalloporphyrin‐Ellipticine” Molecules.
Authors: ETEMAD‐MOGHADAM G. , DING L. , TADJ F. , MEUNIER B.
Published: May 2016

The porphyrin ligand (Ia) is obtained by coupling of the mixed anhydride formed from an ellipticine derivative (preparation described) and ethyl chloroformate with a metal‐free porphyrin bearing an amino function attached by a methylene chain to the p‐phenoxy ring of a meso‐tetraarylporphyrin.
ChemInform Abstract: Highly Reduced Organometallics. Part 26. Tricarbonyl(phosphine)ferrates(2‐), Fe(CO)3(PR3)2‐, and Their Derivatives.
Authors: ELLIS J. E. , CHEN Y.‐S.
Published: May 2016

A two‐step synthesis of (IV) (thermally stable, but air‐sensitive) from the corresponding compounds (I) via the monohydride (IIIa) is developed which may be of general importance for the conversion of other substituted mononuclear carbonyls to the corresponding dinegative anions.
ChemInform Abstract: X‐Ray Structure, Reactivity, and Catalytic Properties of a (Cyclopentadienone)ruthenium Dimer, ((C4Ph4CO)(CO)2Ru)2.
Authors: MAYS M. J. , MORRIS M. J. , RAITHBY P. R. , SHVO Y. , CZARKIE D.
Published: May 2016

The title complex (II) (as well as two isostructural complexes with Me and Ph or p‐chlorophenyl and Ph substituents) is prepared in high yields provided moisture and protic compounds are excluded.
ChemInform Abstract: Stereoselective Intramolecular C‐H Bond Activation in a Dinuclear Iridium Complex.
Authors: HEINEKEY D. M. , MICHEL S. T. , SCHULTE G. K.
Published: May 2016

Reaction of the complex (I) with diazomethane (II) affords the methylene‐bridged dimer (III) without fragmentation of (I), shown by isotopic double‐labeling experiments.
ChemInform Abstract: Tetra(pentafluorophenyl)porpholactone.
Authors: GOUTERMAN M. , HALL R. J. , KHALIL G.‐E. , MARTIN P. C. , SHANKLAND E. G. , CERNY R. L.
Published: May 2016

The porphyrin (I), under the conditions outlined in the scheme, converts to a new type of porphyrinic species, the porpholactone (II), in which one exo C2H2 unit is tranformed to a CO2 unit.
ChemInform Abstract: A New Route to 1,3‐Dienes Using 3‐Methylene‐2,3‐dihydrothiophene S,S‐Dioxide as an Allyl Sulfone and Michael Acceptor: Synthesis of (.+‐.)‐Ipsenol.
Authors: NOMOTO T. , TAKAYAMA H.
Published: May 2016

The diene (I) reacts with nucleophiles such as (II) to give the adducts (III).
ChemInform Abstract: Syntheses of Steroidal Thiazoles: Reactions of Steroidal α‐Bromoketones with Thioacetamide.
Authors: SHAFIULLAH SHAFIULLAH , SIDDIQUI I. H.
Published: May 2016

The structures of the compounds (III) are established on the basis of their analytical and spectral data.
ChemInform Abstract: Syntheses of (1S,2S,3S,4R)‐ and (1R,2R,3S,4R)‐2,3,4‐Trihydroxycyclopentane‐1‐methanol, Carbocyclic Analogues of α‐L‐Arabinofuranose and β‐D‐Ribofuranose.
Authors: TADANO K. , HAKUBA K. , KIMURA H. , OGAWA S.
Published: May 2016

Starting with the protected glucofuranose (I), the title compounds pseudo‐α‐L‐arabinofuranose (VIIIb) and pseudo‐β‐D‐ribofuranose (IXb) are synthesized as outlined in the reaction scheme.
ChemInform Abstract: α‐Acylamino Radical Cyclizations: Application to the Synthesis of a Tetracyclic Substructure of Gelsemine.
Authors: CHOI J.‐K. , HA D.‐C. , HART D. J. , LEE C.‐S. , RAMESH S. , WU S.
Published: May 2016

Treatment of the radical precursors (I) and (IV) with tributyltin hydride and AIBN results in cyclization, forming the products (II) and (V).
ChemInform Abstract: General Methods for Alkaloid Synthesis via Intramolecular Diels‐Alder Reactions. A Concise Formal Total Synthesis of (.+‐.)‐Dendrobine.
Authors: MARTIN S. F. , LI W.
Published: May 2016

Intramolecular Diels‐Alder reaction of the olefinic dienamides (I) forms the cycloadducts (II).
ChemInform Abstract: Gas Phase Water and Hydroxyl Binding Energies for Monopositive First‐Row Transition‐Metal Ions.
Authors: MAGNERA T. F. , DAVID D. E. , MICHL J.
Published: May 2016

M+‐OH2 and M+‐OH binding energies of first‐row transition metals are determined by means of collision‐induced dissociation in a triple‐quadrupole mass spectrometer.
ChemInform Abstract: Sequential Solvation of Atomic Transition‐Metal Ions. The Second Solvent Molecule Can Bind More Strongly Than the First.
Authors: MARINELLI P. J. , SQUIRES R. R.
Published: May 2016

Sequential water and ammonia solvation energies are determined for V+, Cr+, Mn+, Fe+, Co+, and Ni+ by means of collision‐induced dissociation in a triple quadrupole mass spectrometer.
ChemInform Abstract: Disordering and Heat Capacity of Sodium Hexabromouranate(IV).
Authors: GAMBINO M. , GAUNE P. , SZCZEPANIAK W.
Published: May 2016

From the electrical conductivity, heat capacity, and structural data of Na2UBr6 it is suggested that the disordering processes in the cationic and anionic sublattices are to some degree separated.
ChemInform Abstract: Phase Diagrams of Mixtures of CuI with ZnI2, CdI2 and HgI2.
Authors: BLACHNIK R. , STOETER U. +
Published: May 2016

The systems CuI‐ZnI2, CuI‐CdI2 and CuI‐HgI2, investigated by DTA, DSC, dilatometric and X‐ray measurements, resemble each other very closely.
ChemInform Abstract: Extended X‐Ray Absorption Fine Structure Studies on the Structure Change of the Al2O3‐Attached (CoII)4 Catalyst During a CO Oxidation Reaction.
Authors: ASAKURA K. , IWASAWA Y.
Published: May 2016

Highly active Co(II) oxide catalysts are studied during the CO oxidation reaction under atmospheric and high pressure conditions.
ChemInform Abstract: Preparation of Large Semiconductor Clusters via the Pyrolysis of a Molecular Precursor.
Authors: BRENNAN J. G. , SIEGRIST T. , CARROLL P. J. , STUCZYNSKI S. M. , BRUS L. E. , STEIGERWALD M. L.
Published: May 2016

Nanometer‐sized clusters of CdSe (zinc‐blende structure) are prepared by mild pyrolysis of the precursors (III) or (VI).
ChemInform Abstract: Thermal Preparation and Stability of Binary MnII‐MgII Tetrametaphosphates by Means of DTA.
Authors: TROJAN M.
Published: May 2016

The title compounds are prepared by a two‐step procedure.
ChemInform Abstract: Electrochemistry of Tellurium(II) and Tellurium(IV) Dithiocarbamates at Solid Electrodes in Non‐Aqueous Solvents.
Authors: MAZUREK W.
Published: May 2016

The reductions of the compounds (I) involve an overall two‐electron process on the cyclic voltammetry time scale.
ChemInform Abstract: Stereochemical Control in Microbial Reduction. Part 9. Diastereoselective Reduction of 2‐Alkyl‐3‐oxobutanoate with Bakers′ Yeast.
Authors: NAKAMURA K. , MIYAI T. , NAGAR A. , OKA S. , OHNO A.
Published: May 2016

Bakers' yeast reduces esters of 2‐alkyl‐3‐oxobutanoic acid such as (I) to the corresponding hydroxy esters with exclusive (3S)‐stereochemistry.
ChemInform Abstract: Diels‐Alder Reaction of Unactivated 2‐Aza‐1,3‐dienes with Azodienophiles and Tetracyanoethylene. Crystal Structure of 1,2‐Bis(ethoxycarbonyl)‐3‐ethyl‐6‐methyl‐3,5‐diphenyl‐1,2,3,6‐tetrahydro‐1,2,4‐triazine.
Authors: BARLUENGA J. , GONZALEZ F. J. , FUSTERO S. , FOCES‐FOCES C. , HERNANDEZ CANO F. , SAN FELICIANO A.
Published: May 2016

While azo compounds have been widely used as azodienophiles and azo dienes, their reactivity as dienophiles toward 2‐azadienes is almost unknown.
ChemInform Abstract: Intramolecular Reactions of Compounds Derived from Sugars. Part 2. Stereocontrolled Intramolecular Diels‐Alder Cyclizations of 1,6(E,Z),8‐Nonatrienes and 1‐Aza‐6(E,Z),8‐nonatrienes.
Authors: HERCZEGH P. , ZSELY M. , SZILAGYI L. , BATTA G. , BAJZA I. , BOGNAR R.
Published: May 2016

The Diels‐Alder reaction of the E,Z mixtures of the trienes (VI) and (IX) (yield given in g) leads to the exclusive formation of the bicyclic compounds (VII) and (X), respectively.
ChemInform Abstract: Radical Ions in Photochemistry. Part 21. The Photosensitized (Electron Transfer) Tautomerization of Alkenes; the Phenyl Alkene System.
Authors: ARNOLD D. R. , MINES S. A.
Published: May 2016

Alkenes such as (I), (III), or (V), conjugated with a phenyl group, can be converted to nonconjugated tautomers by sensitized (electron transfer) irradiation.
ChemInform Abstract: Generation and Properties of Acetic Anhydride Carbanion.
Authors: KINASTOWSKI S. , KASPRZYK H. , NOWACKI A.
Published: May 2016

In the reaction between ketene (II) and acetate ions (I), the labile acetic anhydride carbanion (III) is formed.
ChemInform Abstract: Kinetics and Mechanism of the Oxidation of Proline by Periodate.
Authors: PASCUAL R. , HERRAEZ M. A. , CALLE E.
Published: May 2016

The highest reaction rate occurs at pH 4‐7. CO2 and pyrrolidone‐(2) form as products without intermediates.
ChemInform Abstract: Sulfonation Reactions of β‐Carbolines.
Authors: CARMONA GUZMAN M. C. , BALON ALMEIDA M. , HIDALGO TOLEDO J. , MUNOZ PEREZ M. A. , LOPEZ POVEDA M.
Published: May 2016

Kinetics and the different mechanisms of the homogeneous sulfonations of β‐carboline derivatives (I)‐(III) are studied.
ChemInform Abstract: Chemical Differentiation of Bilayer Surfaces in Functional Dialkylammonium Ion Vesicles: Observation of Surfactant Flip‐Flop.
Authors: MOSS R. A. , BHATTACHARYA S. , CHATTERJEE S.
Published: May 2016

In contrast to (Ib) the cleavage of p‐nitrophenylate from (Ia) at pH 7.94 is kinetically biphasic.
ChemInform Abstract: Synthesis of Fluorocodlemones.
Authors: TELLIER F. , SAUVETRE R. , NORMANT J.‐F.
Published: May 2016

The difluoroalkenes (III), prepared by alkylation of the trifluoroalkene (I) with the lithium agents (II) and subsequent desilylation, are metalated to give the zinc organyls (V).
ChemInform Abstract: Synthesis, Redox Behavior, and Spin‐Trap Properties of 2,6‐Di‐tert‐butylnitrosobenzene (DTBN).
Authors: CERRI V. , FREJAVILLE C. , VILA F. , ALLOUCHE A. , GRONCHI G. , TORDO P.
Published: May 2016

The nitrosoarene (II) is obtained by smooth oxidation of the corresponding aniline (I) with peroxybenzoic acid.
ChemInform Abstract: Formation of N‐Acetyl‐p‐benzoquinonimine, the Well‐Known Toxic Metabolite of Acetaminophen, by the Reaction of Acetaminophen with Nitrile Under Model Stomach Conditions.
Authors: OHTA T. , ORIBE H. , IDE M. , TAKITANI S.
Published: May 2016

Treatment of acetaminophen (I) with acidic nitrite solution yields a complex reaction mixture.
ChemInform Abstract: Studies on the Preparation of 5‐(β‐Aminoethylthio)isoxazoles.
Authors: DANNHARDT G. , OBERGRUSBERGER I.
Published: May 2016

The thiazolidines (I) are metalated with butyllithium and subsequently coupled with the ester (II) to produce the enaminones (III).
ChemInform Abstract: An Improved Synthesis of 2‐Carbamoyloxymethyl‐1,4‐dihydropyridine.
Authors: SUZUKI K. , USHIJIMA R. , MIYANO T. , NAKAGAWA S.
Published: May 2016

The O‐butynyl carbamates (IV), prepared by consecutive reaction of the alcohols (I) with phosgene (II) and the amines (III), react with ammonium salts, e.g. (V), or ammonia (VI) to give the amino compounds (VII).
ChemInform Abstract: An Efficient Synthesis of the 4a‐Aryl‐6‐oxodecahydroisoquinolines.
Authors: CANTRELL B. E. , PASCHAL J. W. , ZIMMERMAN D. M.
Published: May 2016

The enamine (I) is lithiated with BuLi and then coupled with the oxirane (II) to give the stereoisomeric oxazabicyclononanes (III).
ChemInform Abstract: Compounds with Bridgehead Nitrogen. Part 58. Configurational Assignments to 1‐Methyl‐1‐isopropylperhydro‐oxazolo(3,4‐a)pyridines.
Authors: CRABB T. A. , TRETHEWEY A. N.
Published: May 2016

Protonation of the diastereomeric perhydro‐oxazolopyridines (I) or (IV) gives different proportions of the trans‐fused hydrochlorides (II) or (V) and the O‐outside cis‐fused products (III) or (VI), as shown by NMR.
ChemInform Abstract: Quinolinone Derivatives as Neuroleptic Agents. Part 1. Synthesis and Biological Activities of (4‐Phenyl‐1‐piperazinyl)propoxy‐2(1H)‐quinolinone Derivatives.
Authors: BANNO K. , FUJIOKA T. , KIKUCHI T. , OSHIRO Y. , HIYAMA T. , NAKAGAWA K.
Published: May 2016

The title compounds, e.g. (V), are prepared by etherification of hydroxydihydroquinolones such as (II) with the α,ω‐dihaloalkanes (I) and subsequent coupling with the 4‐substituted piperazines (IV).
ChemInform Abstract: Cyclofunctionalization of Olefinic Urethanes and Ureas with Halogens. Synthesis of 1‐Substituted Spiro(piperidine‐4,4′(3′H)‐quinazoline)‐2′(1′H)‐one Derivatives.
Authors: TAKAI H. , OBASE H. , TERANISHI M.
Published: May 2016

The urethane (I) is treated with bromine in aqueous acetic acid at room temperature to form the cyclization products (II) and (III).
ChemInform Abstract: Formation of Regioisomeric Tetrahydroisoxazolo(2,3‐d)(1,4)benzodiazepines by Kinetic and Thermodynamic Controls.
Authors: MERENDA I. , OTTANA R. , ROMEO G. , ROTONDO E.
Published: May 2016

1,3‐Dipolar cycloaddition of the benzodiazepine N‐oxide (I) with the acrylic acid derivatives (II) gives the regioisomeric isoxazolidines (III) and (IV).
ChemInform Abstract: Synthesis of Macrocyclic Esters: Solid‐Liquid Phase‐Transfer‐Catalyzed Condensations of Diacid Halides and Diols.
Authors: SINGH H. , KUMAR M. , SINGH P.
Published: May 2016

The synthesis of tetraester macrocycles such as (III) or (IV) is described using solid‐liquid phase‐transfer systems with non‐hydroxylic bases such as KF or K2CO3.
ChemInform Abstract: Preparation of Dithiatetrazocines and Secondary Reactions.
Authors: SCHOLZ U. , ROESKY H. W. , SCHIMKOWIAK J. , NOLTEMEYER M.
Published: May 2016

The title compounds (IV) are prepared according to the scheme.
ChemInform Abstract: Synthesis of 2,4(5)‐Bis(hydroxymethyl)imidazoles and 2,4(5)‐Bis((2‐hydroxyethoxy)methyl)imidazoles: Precursors of 2,4(5)‐Connected Imidazole Crown Ethers.
Authors: ZIMMERMAN S. C. , CRAMER K. D. , GALAN A. A.
Published: May 2016

The bis(hydroxymethyl)imidazole (I) is transformed into the bis(hydroxyethoxymethyl) derivative (IV) which is debenzylated by catalytic hydrogenation to give the key intermediate (V).
ChemInform Abstract: Selective Carriers of Ammonium Ions. Part 1. Synthesis and Template Effect of CsCl and X‐Ray Structure and Ionophoric Properties of Polyether Crowns Containing 1‐Methyl‐3,5‐bis(methylene)‐1H‐pyrazole Units.
Authors: NAVARRO P. , RODRIGUEZ‐FRANCO M. I. , FOCES‐FOCES C. , CANO F. , SAMAT A.
Published: May 2016

The bis(chloromethyl)pyrazole is coupled with tetraethylene glycol (II) in the presence of two equivalents of sodium hydride to give the crown ethers (III) and (IV) with 18 or 36 ring atoms.
ChemInform Abstract: First Asymmetric Synthesis of Enantiomerically Pure (1R,2S)‐(‐)‐(1,2‐Epoxypropyl)phosphonic Acid (Fosfomycin).
Authors: GIORDANO C. , CASTALDI G.
Published: May 2016

Synthesis of the chiral phosphonic acid mentioned in the title starts with coupling of cis‐1‐propenylphosphonic acid dichloride (I) with the (S,S)‐tartaric acid diamide (II) followed by bromohydroxylation of (III).
ChemInform Abstract: Acyclic Enol‐ and Ketophosphonates and Cyclic Hydroxyphosphonates from Dialkyl Phosphites and Z‐1,1,1,5,5,5‐Hexafluoro‐4‐hydroxy‐3‐penten‐2‐one.
Authors: FRANCKE R. , ROESCHENTHALER G.‐V. +
Published: May 2016

Reaction of the hydroxypentenone (I) with the dialkyl phosphites (II) gives the γ‐ketophosphonates (III).
ChemInform Abstract: Functionalized Transition Metal Alkyls. Part 2. Synthesis, Crystal Structure, and Reactivity of (η5‐C5H5)W(CO)3‐CH2‐S(O)‐C6H5, an α‐Metallated Sulfoxide.
Authors: KNEUPER H.‐J. , ZIMMERMANN C. , HARMS K. , BOCHE G.
Published: May 2016

The title compounds (II) are obtained according to the scheme.
ChemInform Abstract: Highly Efficient Hydrolytic Cleavage of Adenosine Monophosphate Resulting in a Binuclear Co(III) Complex with a Novel Doubly Bidentate μ4‐Phosphato Bridge.
Authors: CHIN J. , BANASZCZYK M.
Published: May 2016

The Co(III) complex (I) hydrolyzes unactivated phosphate monoesters such as (II) with unprecedented efficiency.
ChemInform Abstract: Thiophenophane Metal Complexes. Part 2. Preparation, Structure, and Properties of Binuclear Copper(II) Complexes and of 2,5,9,12‐Tetrathia(13)(2,5)thiophenophane. Evidence for S‐Coordinated Thiophene.
Authors: LUCAS C. R. , LIU S. , NEWLANDS M. J. , CHARLAND J.‐P. , GABE E. J.
Published: May 2016

The thiophenophane (III) prepared as shown reacts with Cu(II) chloride (IV) to give the binuclear chloride‐bridged Cu(II) complex (V) with only bidentate coordination of the ligand and distorted square planar coordination geometry about each Cu atom.
ChemInform Abstract: Metal Complexes of Biologically Important Ligands. Part 51. Reactions of α‐Amino Acids with Hexachloropalladate(IV). Stabilization of 1‐Pyrroline at Palladium(II).
Authors: WAGNER B. , TAUBALD U. , BECK W.
Published: May 2016

Hexachloropalladate(IV) reacts with an excess of α‐amino acids with reduction of the metal to give Pd(II) complexes of the different type (I)‐(VI) depending on the used amino acid.
ChemInform Abstract: Metallabenzene: Synthesis, Structure, and Spectroscopy of a 1‐Irida‐3,5‐dimethylbenzene Complex.
Authors: BLEEKE J. R. , XIE Y.‐F. , PENG W.‐J. , CHIANG M.
Published: May 2016

From the starting compound (I) (two‐step preparation described earlier) a proton is abstracted to give the title complex (II), which crystallizes in the P21/n with Z=4.