bluuebunny/crossref_metadata_2025 huggingface dataset:
CREDIT AND HOUSING MARKETS IN VIETNAM: EVIDENCE FROM VECM ANALYSIS
Authors: Bui Ngoc Toan
Published: February 2025

This study focuses on examining the role of the credit market in the housing market in the two largest cities of Vietnam, a developing country with limited empirical research on this issue. In specific, the credit market is defined by credit growth, while the housing market is measured by the house price index. The dataset is collected quarterly from Q1 2009 to Q4 2022. By employing the Vector Error Correction Model (VECM) method, the findings reveal that bank credit has a positive impact on housing prices in the long term, a result observed in both of Vietnam's largest cities - Ho Chi Minh City and Hanoi City. Moreover, economic growth and the consumer price index also significantly influence housing prices in Vietnam. Based on these findings, the author suggests implications for promoting the credit market coupled with the development of the housing market. Furthermore, the findings offer practical and meaningful insights not only for Vietnam's cities but also for other developing countries worldwide.
ФОРМУВАННЯ CТРУКТУРИ КАПІТАЛУ БАГАТОНАЦІОНАЛЬНИХ КОРПОРАЦІЙ: НОВИЙ ПІДХІД
Authors: Циганов Сергій , Сініцин Олексій , Примостка Людмила , Циганова Надія , Краснова Ірина
Published: February 2025

Структура капіталу багатонаціональних корпорацій (БНП) є складним і багатовимірним явищем, яке суттєво впливає на їхню операційну ефективність і процеси ухвалення фінансових рішень. У роботі досліджені різноманітні фактори, які впливають на рішення щодо капітальної структури, з акцентом на взаємодію внутрішніх чинників і ринкових умов. Завдяки всебічному аналізові існуючих теорій і емпіричних досліджень, автори виявляють ключові детермінанти, такі як прибутковість, податкові аспекти, бізнес-ризики, можливості зростання, агентські витрати й добробут акціонерів.У світлі цих висновків автори пропонують новий показник, показник сигнальної структури капіталу, що покликаний удосконалити аналіз капітальної структури, відображаючи реальні рішення, які ухвалюють інсайдери самих БНП. Запропоноване співвідношення дозволяє більш точно оцінити, як БНП обирають фінансові стратегії у відповідь на різноманітні внутрішні й зовнішні фактори. Зосереджуючись на намірах і відповідних ухвалених рішеннях, цей підхід забезпечує цінні інсайти щодо труднощів управління капітальною структурою.Результати дослідження підкреслюють важливість досягнення оптимального балансу між борговим фінансуванням і власним капіталом, що може підвищити загальну продуктивність, зменшити вартість капіталу та покращити управління ризиками. Використання цього нового показника допоможе БНП краще адаптувати свої стратегії до динамічних ринкових умов.У дослідженні також переглянуто усталені теорії структури капіталу, зокрема представлено докази значної зміни парадигми серед нефінансових корпорацій США. Результати вказують на перехід до альтернативних стратегій фінансування, що кидають виклик традиційним підходам до боргу, власного капіталу та розподілу дивідендів. Аналізуючи ці нові практики, дослідження пропонує цінні висновки щодо того, як корпорації використовують алокацію капіталу для керування власним відновленням і досягнення довгострокового сталого зростання.
ปัจจัยความสำเร็จของกลุ่มวิสาหกิจชุมชนแปลงใหญ่ผลิตข้าวในจังหวัดพัทลุง
Authors: จันทร์สุด ณัฐนันท์ , ปิ่นแก้ว กชกมล , หวานแก้ว สุขุมาล
Published: February 2025

ที่มาและวัตถุประสงค์: จังหวัดพัทลุงเป็นแหล่งผลิตข้าวที่สำคัญแห่งหนึ่งของภาคใต้ มีวิสาหกิจชุมชนผู้ผลิตข้าวหลายกลุ่ม และมีวิสาหกิจชุมชน 4 กลุ่ม เข้าร่วมโครงการส่งเสริมระบบเกษตรนาแปลงใหญ่มีการดำเนินงานมากว่า 3 ปี  และได้รับผลการประเมินจากกรมส่งเสริมการเกษตรอยู่ในระดับดี งานวิจัยนี้จึงมีวัตถุประสงค์เพื่อศึกษาปัจจัยที่ส่งผลต่อความสำเร็จของวิสาหกิจชุมชนผลิตข้าวที่เข้าร่วมโครงการส่งเสริมระบบเกษตรนาแปลงใหญ่ในจังหวัดพัทลุง และนำเสนอแนวทางในการพัฒนาวิสาหกิจชุมชนผลิตข้าวให้ประสบความสำเร็จและยั่งยืน
ระเบียบวิธีวิจัย: เก็บข้อมูลจากสมาชิกทั้งหมดของกลุ่มวิสาหกิจชุมชนผลิตข้าวที่เข้าร่วมโครงการส่งเสริมระบบเกษตรนาแปลงใหญ่ในจังหวัดพัทลุง จำนวน 4 กลุ่ม  ประกอบด้วย วิสาหกิจชุมชนศูนย์ข้าวชุมชนบ้านปาบ วิสาหกิจชุมชนกลุ่มข้าวชุมชนบ้านไสอ้อ วิสาหกิจชุมชนบ้านเรียนรู้เกษตรธรรมชาติบางแก้ว และวิสาหกิจชุมชนนาแปลงใหญ่บ้านธรรมเถียร จำนวนทั้งหมด 152 คน โดยใช้แบบสอบถามเป็นเครื่องมือในการเก็บรวบรวมข้อมูลครั้งนี้ วิเคราะห์ข้อมูลทางสถิติได้แก่ ค่าเฉลี่ย และส่วนเบี่ยงเบนมาตรฐาน และใช้การวิเคราะห์เนื้อหา (Content Analysis) สำหรับข้อมูลเชิงคุณภาพ
ผลการวิจัย: ผลการศึกษาพบว่าวิสาหกิจชุมชนผลิตข้าวทั้ง 4 กลุ่ม รวมกลุ่มกันเพื่อลดต้นทุนการผลิตมีระยะเวลาการดำเนินงาน 3-14 ปี โดยมีสินค้าหลักคือ ข้าวเปลือกและข้าวสาร จากการศึกษาปัจจัยความสำเร็จของการดำเนินงาน พบว่า ปัจจัยด้านผู้นำและปัจจัยด้านสมาชิกเป็นปัจจัยที่มีระดับความคิดเห็นอยู่ในระดับมากทั้ง 4 กลุ่ม โดยปัจจัยด้านผู้นำ พบว่าผู้นำสามารถจูงใจให้สมาชิกทำงานร่วมกันได้ และผู้นำช่วยให้เกิดการประสานงานที่ดีระหว่างสมาชิกมีระดับความคิดเห็นอยู่ในระดับมาก และในส่วนของปัจจัยด้านสมาชิก สมาชิกมีความสามัคคี สมาชิกพอใจกับสภาพแวดล้อมในการทำงาน สมาชิกมีส่วนร่วมในการเลือกผู้นำและกรรมการ และสมาชิกมีส่วนร่วมในการวางแผนและแก้ไขปัญหามีระดับความคิดเห็นอยู่ในระดับมาก แนวทางในการพัฒนาวิสาหกิจชุมชนผลิตข้าวให้สามารถดำเนินงานไปได้อย่างมีประสิทธิภาพและยั่งยืนควรให้ความสำคัญกับผู้นำของกลุ่มและสมาชิกกลุ่ม โดยในการเลือกผู้นำควรพิจารณาภาวะความเป็นผู้นำและได้รับการยอมรับจากสมาชิกในการบริหารจัดการ สมาชิกกลุ่มควรมีความสามัคคี และเป็นแบบอย่างที่ดี องค์ประกอบเหล่านี้จะเป็นปัจจัยสำคัญในการที่จะช่วยให้กลุ่มสามารถดำเนินงานได้ต่อเนื่องและประสบความสำเร็จ
อภิปรายผล: ผู้นำกลุ่มที่มีวิสัยทัศน์ มีความสามารถในการบริหารจัดการ และได้รับการยอมรับจากสมาชิกจะสามารถสร้างแรงจูงใจให้สมาชิกทำงานร่วมกันได้อย่างมีประสิทธิภาพ คุณลักษณะของสมาชิกเป็นอีกปัจจัยที่มีความสำคัญในการขับเคลื่อนการดำเนินงานของกลุ่ม สมาชิกกลุ่มควรพัฒนาตนเองให้มีความรู้ใหม่ ๆ อยู่เสมอ มีความสามัคคี และเป็นแบบอย่างที่ดี องค์ประกอบเหล่านี้จะเป็นปัจจัยสำคัญในการที่จะช่วยให้กลุ่มสามารถดำเนินงานได้ต่อเนื่องและประสบความสำเร็จ
บทสรุป: วิสาหกิจชุมชนผลิตข้าวทั้ง 4 กลุ่ม มีปัจจัยด้านผู้นำและสมาชิกเป็นปัจจัยที่มีระดับความคิดเห็นอยู่ในระดับมาก ดังนั้นแนวทางในการพัฒนาวิสาหกิจชุมชนผลิตข้าวให้สามารถดำเนินงานไปได้อย่างมีประสิทธิภาพและยั่งยืนควรให้ความสำคัญกับการพัฒนาผู้นำของกลุ่มและสมาชิกกลุ่ม
Introduction to Management in the Hospitality Industry (By Clayton W. Barrows, Tom Powers, & Dennis R. Reynolds)
Authors: Suksutdhi Thanasit
Published: February 2025

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Projetos de Inclusão social: motivos para ingressar no balé
Authors: Cunha Marluce Fabíola Coelho da , Vianna José Antonio
Published: February 2025

Este estudo teve como objetivo verificar os motivos de praticantes e de ex-praticantes de balé para ingressarem na oficina de balé clássico em Projeto de Inclusão Social. A análise documental permitiu a identificação de 38 alunos em atividade (Fem. = 36; Masc. = 2), com média de 12,5 anos de idade, 19 meninas que evadiram (M =13,5 anos de idade) e 25 egressos (Fem. = 23; Masc. = 2) com média de 21,7 anos de idade, que responderam ao questionário semiestruturado aplicado nos investigados. A Triangulação de Métodos foi utilizada na análise dos dados. Os dados quantitativos foram tratados através de estatística descritiva e os dados qualitativos passaram pela descrição, decomposição e síntese. Os investigados percebem como principais motivos para adesão ao programa, o atendimento das expectativas de aprendizagem da modalidade e do domínio da técnica do balé, como uma possibilidade de vivenciar as apresentações da dança e de profissionalização.
Estilo de vida e controle glicêmico em pacientes com diabetes mellitus tipo 2: uma revisão integrativa da literatura
Authors: Borges Alice Lima , Costa Sueli de Souza , Junior José Braz Costa Castro , Soares Beatriz Lima , Leite Nilson Otávio Sampaio , Carmo Francisco Henrique Rodrigues Moraes do
Published: February 2025

O diabetes mellitus tipo 2 é uma doença com alta prevalência global e morbimortalidade. O tratamento exige medicas farmacológicas e não farmacológicas, sendo avaliado pela hemoglobina glicada. OBJETIVO: Identificar os principais fatores relacionados ao estilo de vida que estão associados ao controle glicêmico em pacientes diabéticos. METÓDO: O estudo trata-se de uma revisão integrativa que buscou artigos publicados nos anos de 2014 a 2023 nas bases de dados BVS, SciELO e PUBMED, publicados em português, inglês ou espanhol, segundo descritores selecionados dos Descritores em Ciências da Saúde (DeCs) e que respondessem à pergunta norteadora definida a partir do acrônimo PICO.  Para a seleção dos artigos utilizou-se o fluxograma PRISMA 2020. RESULTADOS:  13 artigos compuseram a amostra. Houve associação benéfica entre o controle glicêmico e uma dieta cetogênica hipocalórica, alterações na quantidade das refeições, atividade física, manejar o estresse, hábitos de saúde bucal, usar estratégias para controle de peso e consumo frutas e fibras alimentares insolúveis. Hábitos como adição extra de sal, consumo de leite e derivados, padrão alimentar rico em fast-foods, açúcar e grãos refinados, pular o café da manhã e jantar tarde da noite, fazer refeições noturnos, longas jornadas de trabalho, consumo excessivo de álcool e tabagismo foram relacionados a um controle glicêmico ruim. CONCLUSÃO: Diversos fatores do estilo de vida estão associados ao controle glicêmico de pacientes com DM2, refletindo o complexo manejo desses pacientes e a necessidade de mais pesquisas, visto que ainda falta consenso sobre alguns deles.
Often neglected steps in transforming drug solubility from single measurement in pure water to physiologically-appropriate solubility-pH
Authors: Avdeef Alex
Published: February 2025

Background and purpose: The solubility of weakly-ionizable drugs in pure water, Sw, is commonly measured. The pH-dependent properties of the saturated solutions can be surprisingly complex in subtle ways.  This commentary examines the characteristics of such measurements through case studies of 32 free acids, bases, and ampholytes (including crocetin, glibenclamide, mellitic acid, quercetin, bedaquiline, brigatinib, imatinib, celecoxib, and lysine), using published water solubility data. Computational approach: Usually, in such saturated solutions, the ionic strength, Iw, is close to zero.  When the pH is adjusted away from pHw, the ionic strength increases, substantially in some cases (e.g. Iw > 10 M at pH 7.4 for mellitic acid and lysine). This change in ionic strength alters the activities of the species in solution. The corresponding equilibrium constants used to calculate the concentrations of these species must be adjusted accordingly.  Here, the Stokes-Robinson hydration theory, slightly modified with Setschenow ‘salting-out’ constants to account for solvent interactions with unionized drugs, was used to estimate activity coefficients.  The calculations were performed with the pDISOL-X program.  Key results: Given reliably-measured values of Sw and pKa of the drugs and assuming that the Henderson-Hasselbalch equation is valid, a method is described for (i) adjusting the measured Sw values at ionic strength, Iw ~ 0 M, to values expected at Iref = 0.15 M (or at any other reasonable reference value), (ii) determining the water pHw in saturated solutions of added neutral-form drugs; (iii) determining the intrinsic solubility, S0, both at Iw and Iref, and (iv) using analytic-continuation in the equilibrium mass action model to deduce the solubility values as a function of pH, harmonized to a selected Iref.  For highly soluble drugs, whose Iw exceeds 0.15 M, the intrinsic solubility values appear to depend on the amount of excess solid added. Conclusion: This commentary re-emphasizes that measured Sw is not generally the same as S0.  It is stressed that transforming measured drug solubility in pure water to an ionic strength level that is physiologically appropriate would better match the conditions found in biological media, potentially improving applications of solubility in pharmaceutical research and development.
A Study on Facial Feature Extraction and Emotional Analysis Using ML
Authors: Adhyaru Kushal , Ishan  , Harshitha Dyapa , Mundlur Rohan Pradev , Kumar Dubasi Pavan , Roshan Mallipeddi , Velaga Ashish Chowdary , Supriya Yerrabothula Sai , Guha Srirupa
Published: February 2025

Human beings communicate in two ways- verbal and non-verbal. Facial expressions are a really important factor when it comes to non-verbal communication. This is because we humans have the capability of recognizing emotions and understanding them. A facial emotion recognition system is a very crucial component in human machine interaction. This is because we can apply the knowledge of identified emotions in various fields and valuable conclusions can be made. While it is widely used in human-machine interaction, it can also be used for patient monitoring and for studying the emotions of an individual suspected to have malicious motives. Human emotion recognition has an indispensable role in interpersonal relationships as well. You can judge a person’s emotions by their speech, hand and body movements and undoubtedly their facial expressions. We can also use emotion recognition system to analyze a customer’s reaction on seeing a particular product, advertisement, information etc. The service center will be benefitted from this approach as they can modify their center according to the response received. In a very basic form of a facial expression recognition system, there is an input sensing device like a webcam which takes the picture of the subject and then transfers it to the computer. Representative features are extracted from the face after the facial area has been detected. Pre-processing of the data is done and it classified into expressions such as anger, disgust, surprise, happy, neutral etc. using a classifier. This project presents dynamic model of emotions with eigen space-based approach as its basis. Eigen space is a feature space that is responsible for encoding the variations in eigen faces. The eigen faces can be thought of as a set of feature space which characterizes the overall variations among the face images.
Preparación del docente para la virtualización de la asignatura de Emprendimiento y Gestión en el Bachillerato
Authors: Vera-Párraga Celia María , Villacis-Toapanta Nely Llopanguita , Vázquez-Zubizarreta Gretel , Molina-Barzola Mónica Mayra
Published: February 2025

El estudio tuvo como objetivo identificar las necesidades de preparación del docente para la virtualización de la asignatura de Emprendimiento y Gestión en el Bachillerato en las entidades educativas de la provincia de Tungurahua, en el Ecuador. Para ello se trabajó con un enfoque cuantitativo y se utilizó una encuesta previamente diseñada con 6 dimensiones: información-comunicación, creación de contenidos, recursos, medios, capacitación y disposición, las cuales se evaluaron a través de ítems que se valoraron mediante escala de Likert, entre 1 a 5. El cuestionario obtuvo un Alfa de Cronbach de .641 indicando una consistencia internada adecuada. La población fue de 152 docentes y la muestra de 112. Los hallazgos indicaron que los docentes reconocen la necesidad de mejorar sus conocimientos en el manejo de herramientas digitales para la accesibilidad a la información y creación de contenidos en el aprendizaje. Además, reconocen no emplear frecuentemente medios y recursos del contexto digital en el proceso de enseñanza-aprendizaje, asumiendo también el no haber accedido a capacitaciones. Se concluye que los docentes de Tungurahua no están preparados para virtualizar la asignatura de Emprendimiento y Gestión y necesitan de apoyo. Por ello se propone un taller de capacitación para fortalecer el trabajo de incorporación de las tecnologías en la educación, así como diseñar un entorno virtual de aprendizaje viable en beneficio de los estudiantes y de la asignatura Emprendimiento y Gestión
Comparación entre el implante coclear óptico y el implante coclear eléctrico en personas con déficits auditivos
Authors: Sailema-Ullco Jéssica Belén , Alfonso-Morejón Eduardo Arsenio
Published: February 2025

La pérdida auditiva es considerada una patología presente a nivel mundial que afecta notablemente la calidad de vida de quienes lo padecen; actualmente el implante coclear (IC) es el único tratamiento de elección para la pérdida auditiva de profunda a severa, ya que este dispositivo estimula las neuronas del ganglio espiral (NGE) y son capaces de devolver la audición de forma parcial; existen dos tipos: el implante coclear eléctrico (ICE) convierte el sonido en pulsos eléctricos que llegan a la cóclea y estimulan al ganglio espiral dando sensación de audición en ausencia de células ciliadas funcionales, mientras que el implante coclear óptico (ICO) estimula la neurona por medio de luz y usa la organización tonotópica coclear ofreciendo mayor selectividad espectral y por ende mejora la audición en entornos ruidosos y la comprensión de la música. Los IC son intervenciones comunes en niños y adultos con PA. Así como brinda beneficios, se presentan complicaciones luego de la colocación del implante. La estimulación eléctrica es de uso común en este ámbito, antigua pero no de elección por el momento, mientras que la estimulación óptica es nueva pero prometedora en el campo de la audición. Los sistemas actuales de implantación coclear resultan eficaces en personas sordas, ya que es posible comprender el habla incluso vía telefónica, a pesar de que aún tiene ciertas limitaciones es una señal para continuar con la investigación y llegar más lejos.
ОЦЕНКА СОСТОЯНИЯ НОВОРОЖДЕННЫХ ОТ ПЕРВОРОДЯЩИХ ЖЕНЩИН ПОЗДНЕГО РЕПРОДУКТИВНОГО ВОЗРАСТА
Authors: Гулямова Муяссар , Турсунбаева Феруза , Ходжиметова Шахноза , Темирова Мадина
Published: February 2025

Состояние новорожденных теснейшим образом зависит от состояния репродуктивного здоровья матери. На наш взгляд, изучение малоизученных аспектов «поздней» беременности позволит снизить материнскую и перинатальную смертность и заболеваемость. В литературе имеются единичные данные о клинической оценке состояния новорожденных, родившихся у женщин позднего репродуктивного периода.  Цель исследования: Оценка состояния новорожденных от первородящих женщин позднего репродуктивного возраста. Материалы и методы. 76 новорожденных детей, родившихся с гестационным возрастом 29–42 недели, которые были разделены на две группы: I группу составили - 42 новорожденных, родившихся от матерей позднего репродуктивного возраста, ІI группу - 34 новорожденных детей, рожденных от матерей фертильного возраста. Результаты Установлено, что   изложенные состояния в оценке новорожденных  в первые часы жизни, рожденные от первородящих матерей  позднего репродуктивного возраста более подтверждены патологическому процессу, который и в периоде аутостабилизации внутренних органов. Оценка состояния здоровья новорожденных, и дальнейшего их развития, даст возможность неонатологам и педиатрам при необходимости оказать им своевременную квалифицированную помощь.
Assessing inhalation intake of microplastics using MPPD model
Authors: Choi Yurim , Choi In Woo , Kwon Jung-Hwan
Published: February 2025

Increasing evidence of the presence of small microplastics in human tissues necessitates research on their intake routes and internalization. Among two major routes of exposure to microplastics (MPs), inhalation pathways are less investigated than ingestion pathways. In this study, quantitative estimation of microplastics intake and internalization was conducted using the multi-path particle dosimetry (MPPD) model by US Environmental Protection Agency assuming three representative particle size distributions (i.e., Power law, unimodal, and biomodal distributions) of cylindrical MPs within the aerodynamic diameter between 0.1 and 10 μm at the aspect ratio of 3:1. Assuming the default atmospheric concentration of MPs at 0.1 μg m–3, the estimated mass deposition in human lungs ranged 19.1–49.9 μg. Although sensitivity analysis revealed that estimated mass deposition of MPs in human lungs were not much different among three particle size distributions, deposition in the pulmonary region was strongly affected by the type of size distributions. Because of suspected health symptoms of MPs in the pulmonary region and the slower clearance in this region, it is of urgent needs to characterize MP size distribution in the inhalable particle size range (0.1–10 μm) and to analyze MPs in the same size range in human respiratory tissues.
TOXOPLASMOSE CONGÊNITA NO SUL E SUDESTE DO BRASIL: UMA DOENÇA NEGLIGENCIADA?
Authors: Marques Izadora Holz , Maximila Rafaella Zanetti , Brião Paula Seixas Sallaberry , Ruffatto Rafaela Mezzomo , Do Amaral Nicoli Farezin , Rodrigues Maria Isabeli de Almeida , Pacheco Clara Chagas , De Menezes Letícia Oliveira
Published: February 2025

INTRODUCTION Toxoplasmosis is a chronic infection caused by the parasite Toxoplasma gondii, which crosses the placental barrier, causing serious and often irreversible problems for the physical and motor development of neonates, newborns and children. Prenatal care is relevant for screening in susceptible pregnant women and rapid initiation of treatment. In Brazil, the prevalence is 5-23 infected children per 10,000 live births. According to the high prevalence of this infection in Brazil, can we say that congenital toxoplasmosis is a neglected disease? OBJECTIVE To evaluate congenital toxoplasmosis rates in the South and Southeast of Brazil and, thus, perform a comparative analysis with Brazilian data in the 2019-2022 period. METHODS This is a cross-sectional, descriptive ecological study with a quantitative approach, covering a time-series analysis of congenital toxoplasmosis indices in the South and Southeast, between 2019 and 2022. RESULTS: Data show a significant increase in cases of newborns with congenital toxoplasmosis in Brazil. The country, in the period from 2019 to 2022, notified the total number of 12,885 new cases. And in the same period, the states of the South and Southeast presented 7,122 new cases – equivalent to 55.3% of the national data. It was also evidenced that among the states with the most reported cases of congenital toxoplasmosis in the Southeast was Minas Gerais (MG), followed by São Paulo (SP). As for the states in the South region, Rio Grande Do Sul (RS) is highlighted, followed by the state of Paraná (PR). CONCLUSION It is of paramount importance to perceive the relevance of the theme presented for a better approach and, consequently, a better outcome for the growing number of cases. Further research on the theme is extremely necessary, as well as a more accentuated look at the importance of well-performed prenatal care.
EXPLORAÇÃO DA INTERAÇÃO ENTRE PEPTÍDEOS ANTIMICROBIANOS E RADIAÇÃO GAMA PARA O DESENVOLVIMENTO DE BIOSSENSORES
Authors: Garbim Fabiane Modenese , Bandeira João N. C. , Pereira Giulianna S. , De Lima Marcela R. , Serrano Nadja F. G. , Boareto-Mendes Álvaro J. , Araújo-Moreira Fernando M.
Published: February 2025

A crescente evolução tecnológica e os desafios na área nuclear exigem abordagens inovadoras que integrem conhecimentos de diferentes áreas. O presente estudo propõe uma pesquisa unindo a ciência nuclear à biotecnologia na investigação do potencial de peptídeos antimicrobianos (PAMs) derivados da bactéria Paenibacillus polymyxa como materiais sensíveis à radiação ionizante gama. A pesquisa se baseou em uma revisão bibliográfica abrangente e na avaliação experimental da atividade de peptídeos antimicrobianos (PAMs) derivados da bactéria Paenibacillus polymyxa antes e após a exposição à radiação gama. Os PAMs selecionados foram expostos a diferentes doses de radiação gama (0,5, 1,0, 4,0 e 10,0 Gy) utilizando um irradiador Gamacell 220 com fonte de Co-60. A atividade antimicrobiana dos peptídeos foi avaliada por meio do teste de difusão em agar, utilizando uma variedade de microrganismos de relevância clínica e ambiental, incluindo Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Listeria monocytogenes e Candida albicans. Estes microrganismos foram selecionados com base em sua importância médica como agentes causadores de infecções, e por representarem diferentes classes de patógenos (bactérias Gram-positivas e Gram-negativas). Os resultados obtidos por meio da revisão bibliográfica e testes preliminares permitiram avaliar o potencial dos PAMs como elementos detectores em biossensores e como agentes antimicrobianos em ambientes contaminados por radiação, devido a sua capacidade de gerar variações detectáveis em suas propriedades físico-químicas quando expostos à radiação ionizante gama, permitindo a detecção rápida e precisa de níveis de radiação gama. Essa abordagem inovadora visa superar as limitações dos métodos tradicionais de detecção, que podem ser lentos, caros e complexos. A pesquisa fundamentou-se na revisão da literatura que identificaram peptídeos promissores com atividade antimicrobiana significativa em Paenibacillus polymyxa e a resistência desses PAMs à radiação ionizante, avaliando seu limiar de eficiência após a exposição. A capacidade dos PAMs de apresentar um limiar à radiação e manter sua atividade antimicrobiana os torna candidatos ideais para o desenvolvimento de biossensores portáteis e de resposta rápida, com custo acessível, de fácil reprodutibilidade, alta sensibilidade e outras características que espera-se de um biossensor eficiente, que podem ser aplicados em diversas áreas desde monitoramento, tais como ambiental, proteção civil, segurança pública e defesa nacional.
PROCESSO LICITATÓRIO PARA AQUISIÇÃO DE AERONAVES USADAS: EFICIÊNCIA E ECONOMICIDADE NOS PROCESSOS LICITATÓRIOS DA CASA MILITAR DO PARANÁ
Authors: Maceno Alessandro Eduardo
Published: February 2025

Este estudo analisa os processos licitatórios para aquisição de aeronaves usadas pela Casa Militar do Estado do Paraná nos anos de 2020 e 2025, considerando a transição da Lei nº 8.666/1993 para a Lei nº 14.133/2021. A pesquisa, baseada em um Relato de Experiência, identificou desafios e avanços na adoção dessa modalidade de aquisição, anteriormente não explorada pelo Estado. A metodologia envolveu análise documental, pesquisa de mercado e comparação entre os processos licitatórios. Os resultados demonstram que a compra de aeronaves usadas é uma alternativa viável e vantajosa, garantindo economicidade e eficiência, sem comprometer a segurança operacional. A experiência adquirida contribuiu para o aprimoramento das práticas licitatórias, possibilitando maior competitividade e transparência na aquisição de bens públicos.
CAPACITAÇÃO DE PROFESSORES EM TECNOLOGIAS INCLUSIVAS: O USO DAS TECNOLOGIAS NA INCLUSÃO DE ALUNOS COM AUTISMO
Authors: Penha Maria Cleonice Santos de Melo , Dantas Liliane de Araújo , Nicolau Patricia Cardoso , de Souza Nelia Elisabete Fagundes , Teixeira Elizabete Cesar de Rezende
Published: February 2025

Para que os professores sejam capacitados em tecnologias inclusivas para alunos com autismo, de forma que todos tenham igualdade de oportunidades educacionais, os educadores são treinados para oferecer a eles ferramentas tecnológicas, permitindo atender às suas necessidades únicas e ajudar a criar um ambiente escolar inclusivo e acolhedor. Este treinamento permite que os professores adquiram gradualmente habilidades que são essenciais para utilizar princípios didáticos apropriados, levando à formação de um processo educacional que seja benéfico para todos os alunos, particularmente para alunos com autismo. Essas tecnologias inclusivas também fornecem aos educadores ferramentas para personalizar o aprendizado, levando em conta as nuances inerentes a cada aluno, o que, por sua vez, pode impulsionar o engajamento e a participação na sala de aula. É dentro dessa perspectiva que o treinamento contínuo para professores contribui para torná-los defensores de uma educação inclusiva, onde um ambiente escolar é capaz de valorizar a diversidade e preparar todos os alunos para interagir positivamente e participar ativamente da vida escolar. Portanto, a capacitação dos instrutores em tecnologias inclusivas não é apenas para ajudar os educadores a desenvolver habilidades, mas também para reforçar uma cultura inclusiva, uma cultura onde todos os alunos, apesar de suas dificuldades, recebam uma educação de qualidade.
INTELIGÊNCIA ARTIFICIAL PERSONALIZADA: CRIAÇÃO DE SISTEMAS QUE AJUSTAM O MATERIAL DIDÁTICO ÀS DEMANDAS DE INDIVÍDUOS COM AUTISMO
Authors: Francisconi Suzana Brentam , Dantas Liliane de Araújo , Silva Gleyton de Moura Ferreira , Klauch Jorge José , Patrício Valdemir Rosa
Published: February 2025

Para que os professores sejam capacitados em tecnologias inclusivas para alunos com autismo, de forma que todos tenham igualdade de oportunidades educacionais, os educadores são treinados para oferecer a eles ferramentas tecnológicas, permitindo atender às suas necessidades únicas e ajudar a criar um ambiente escolar inclusivo e acolhedor. Este treinamento permite que os professores adquiram gradualmente habilidades que são essenciais para utilizar princípios didáticos apropriados, levando à formação de um processo educacional que seja benéfico para todos os alunos, particularmente para alunos com autismo. Essas tecnologias inclusivas também fornecem aos educadores ferramentas para personalizar o aprendizado, levando em conta as nuances inerentes a cada aluno, o que, por sua vez, pode impulsionar o engajamento e a participação na sala de aula. É dentro dessa perspectiva que o treinamento contínuo para professores contribui para torná-los defensores de uma educação inclusiva, onde um ambiente escolar é capaz de valorizar a diversidade e preparar todos os alunos para interagir positivamente e participar ativamente da vida escolar. Portanto, a capacitação dos instrutores em tecnologias inclusivas não é apenas para ajudar os educadores a desenvolver habilidades, mas também para reforçar uma cultura inclusiva, uma cultura onde todos os alunos, apesar de suas dificuldades, recebam uma educação de qualidade.
The ABCs of using the Internet.” A techno-pedagogical proposal for digital inclusion, for people aged 45 to 54
Authors: Facio Ortega María Concepción Valentina
Published: February 2025

Introduction: The article analyzed the widening of the digital divide in terms of age, geographical context, educational level and economic occupation. It focused on the 45-54 age group, who faced greater challenges in accessing and using digital technologies. Lack of infrastructure, affordability and digital literacy were identified as the main factors hindering their digital inclusion.Development: During the COVID-19 pandemic, inequality in Internet access became more evident, especially affecting vulnerable sectors such as people without formal education or with low incomes. The government implemented strategies focused on infrastructure, but neglected digital literacy, which limited the real use of ICT. According to INEGI (2023), 33.3% of people without mobile devices mentioned economic problems as the main cause, while 15.7% indicated lack of knowledge in their use. Generation X, being at an intermediate stage of technology adoption, needed specific strategies to bridge the digital divide. An intervention model based on workshops called “The ABCs of Using the Internet” was proposed to facilitate the acquisition of digital skills.Conclusion: The study concluded that the digital divide was not only related to infrastructure, but also to training and affordability. Digital literacy was presented as a necessity and not as a choice. The importance of creating adequate training spaces to guarantee the inclusion of all people was highlighted, preventing the lack of access to technology from deepening social inequality.
The use of social networks and cell phones in the context of the reading and writing workshop subject
Authors: Bravo Moreno José Porfirio , López Paniagua Rosalía
Published: February 2025

Even though the use of social networks is a social phenomenon that has been studied in recent decades, in the situation caused by the lockdown during the Covid-19 pandemic, distance learning emerged and the use of social networks became widespread in the fields of educational planning and teaching strategies at all levels and in all educational institutions in Mexico. The challenge was great and today we can talk about assertive digital communication, that is to say, a before and after in the use and administration of this digital resource as a didactic strategy, to the point that in the specific case of the subject Reading and Writing Workshop, educational innovations were implemented that are still being applied today.
Rehabilitation Nursing Care to a person with Immobility Syndrome due to Intestinal Pseudo-Obstruction: Case Report
Authors: Gouveia Ana , Redondo Ana Cristina , Fonseca Patrícia , Severino Sandy , Sousa Luís
Published: February 2025

Introduction: Intestinal Pseudo-Obstruction is a chronic condition that, when associated with immobility syndrome, can translate into the loss of independence, decreased functional capacity and reduced quality of life. The management of the disease, the consequences and the expectations of the person being cared for are a permanent challenge for Rehabilitation Nursing.Objective: To describe the benefits of implementing a Rehabilitation Nursing program to the person with immobility syndrome due to chronic intestinal pseudo-obstruction.Case Report: Descriptive study, case report type of a person with immobility syndrome due to chronic intestinal pseudo-obstruction. After identifying the nursing diagnoses, a care plan was developed based on Nursing Ontology, and an individualized rehabilitation program was implemented, in a home setting.Conclusion: With the implementation of the program, there were gains in increased muscle strength, improved balance, increased tolerance to activity and independence in activities of daily living. The improvements of the implementation of this rehabilitation program corroborate that the Rehabilitation Nurse should include in their intervention plans exercises focused on re-education to exertion and muscle strengthening to mitigate the complications resulting from prolonged immobility and the underlying disease, motivating and involving the person in care.
Mandibular Fracture Due to Gunshot Injury with Reconstruction Using Osteosynthesis: case Report
Authors: Vallejo-Navas Jorge M. , Cabrera Arévalo Claudia E.
Published: February 2025

Introduction: mandibular fractures caused by firearms are complex injuries that require specialized surgical management. Objective: to describe the surgical treatment of a multifragmentary mandibular fracture caused by a gunshot wound, using osteosynthesis techniques. Case Report: we present the case of a 29-year-old male patient who sustained a fracture in the body and left mandibular angle after a gunshot injury. The treatment consisted of an initial surgical debridement to prevent infections, followed by the placement of Erich arch bars for maxillomandibular stabilization. A second surgical procedure was performed for reconstruction through open reduction and internal fixation (ORIF), using 2.4 mm osteosynthesis plates with bicortical screws, via a Risdon-type extraoral approach. This approach allowed excellent exposure of the bone fragments, ensuring proper alignment while preserving the marginal branch of the facial nerve. The patient had an uneventful postoperative recovery, achieving adequate mandibular function. Conclusion: this case highlights the importance of timely and precise intervention to ensure complete functional recovery.
The Effect of Lifestyle Measures on Pandemic Disease Prevention among Older Adults
Authors: Ahmed Mersal Fathia , Megahed Ibrahim Ateya , El Sattar Ali Rasmia Abd , Abdou Eltaib Fatma , Abu negm Lobna Mohamed Mohamed
Published: February 2025

Introduction: The COVID-19 pandemic has highlighted the vulnerability of older adults, who are the most susceptible population group. Promoting healthier habits like diet, exercise, sleep, and reducing smoking and alcohol consumption can reduce infection risks and prevent severe cases. Public authorities are focusing on elderly adults, but attitudes and compliance with these measures remain largely unknown. The study aims to evaluate older adults' lifestyle measures toward the prevention of COVID-19. Methods: A study involving 350 older adults was conducted at El Fayoum General Hospital and Abshway Central Hospital. A descriptive design was used, and data was collected using a structured interviewing questionnaire. The questionnaire assessed personal characteristics, health status, and self-reported lifestyle practices. The study aimed to understand the health status and lifestyle practices of older adults in El Fayoum.Results: The main results of the study revealed that 30% of the studied group had good personal hygiene, 45.1% had moderate physical activity, 23.1% had good nutrition, 17.1% did not smoke, 30.6% of the studied group did not manage their stress levels, 50.7% had poor social relations. Also,91.7% of them practiced moderate safety lifestyles, while 9% of them had undesirable lifestyles. Additionally, 61.7% of older adults had poor health status. Conclusions: The COVID-19 pandemic has significantly impacted older adults, especially those with chronic illnesses. Implementing preventive measures and managing chronic conditions is crucial to reduce infection risk and improve health outcomes, especially through targeted interventions.
The future insights of AI Applications in Hematology diseases diagnosis and prognosis: Review Article
Authors: Ali Waggiallah Hisham , Al-Garni Abdulkareem , Ali M Ghazwani Aisha , Bin Shaya Abdulkarim S. , Al Shmrany Humood , Elmosaad Yousif
Published: February 2025

Artificial intelligence (AI) is rapidly altering the field of hematology, providing novel approaches to diagnosis, prognosis, and management of hematological illnesses. AI technologies, including machine learning (ML) and deep learning (DL), allow for the analysis of massive volumes of clinical, genetic, and imaging data, resulting in more accurate, rapid, and individualized care. In diagnostic hematology, AI is transforming blood smear analysis, bone marrow aspirations, and genomic profiling by automating cell classification, detecting anomalies, and discovering critical genetic changes associated with blood illnesses. AI-powered models are also improving prognostic skills by predicting disease progression, treatment response, and risk of relapse in illnesses such as leukemia, lymphoma, anemia, and myeloproliferative disorders. Furthermore, AI applications in precision medicine enable clinicians to adapt medicines based on individual genetic profiles, thereby increasing therapeutic success and reducing unwanted effects. The combination of AI and modern technology such as wearable health monitors and real-time diagnostic tools promises to improve patient management by providing proactive care via continuous monitoring and adaptive treatment options. As AI develops, it has enormous potential in hematology, enabling early identification, optimizing treatment regimens, and ultimately improving patient survival and quality of life. This study investigates the future implications of AI applications in hematology, emphasizing their revolutionary impact on diagnosis, prognosis, and individualized treatment techniques.
Implementación de Inteligencia Artificial para la Personalización del Aprendizaje en Educación Superior
Authors: Vaca Zambrano Segundo Enrique , Machado Herrera Paúl Hernán , Huera Paltán Byron Paúl , Farez Atiencia Jean Carlos , Farez Atiencia Jean Carlos
Published: February 2025

Introduction: The research focuses on the implementation of artificial intelligence to personalize learning in higher education, considering its potential to enhance educational quality, adapt the teaching process, and enable adaptive learning tailored to the individual. Methods: A documentary review methodology was followed to analyze recent academic sources, prioritizing studies that examine the impact of AI on personalized learning. The documentary analysis provided insights into the advancements, limitations, and opportunities of AI in the specific context of higher education. The article includes a total of 45 bibliographic citations obtained from academic databases such as Latindex, Scielo, Scopus, and Google Scholar. Objective: To analyze how the implementation of artificial intelligence (AI) can personalize learning in higher education. Results: The findings demonstrate that AI helps personalize higher education using intelligent tutoring systems and big data analysis combined with self-regulated learning models. These models help tailor content and guidance to everyone. However, the study also emphasizes the importance of addressing ethical challenges such as privacy and equitable access to AI. Conclusions: Artificial intelligence can be considered a valuable tool for personalizing learning in higher education, with the potential to improve students' academic performance and motivation. However, its use must be framed within rigorous policies to ensure ethical practices. Additionally, further empirical research is recommended to better understand the impact of AI in various educational contexts and to guarantee that these innovations benefit all students.
Urban Transportation and Rising CO Emissions: A Case Study of East Jakarta and its Public Health Impacts
Authors: Ernyasih Ernyasih , Anwar Mallongi  , Munaya Fauziah  , Gilang Anugerah Munggaran  , Firda Ayu Salsabilla  , Wesam AL Madhoun  , Fini Fajrini  , Taufiqurrochman Taufiqurrochman
Published: February 2025

Introduction: Carbon monoxide (CO) emissions from urban transportation present a critical challenge for air quality, public health, and environmental sustainability. East Jakarta, with its rapid motorization and chronic traffic congestion, serves as a case study for the broader impacts of urban CO pollution. This study investigates the correlation between CO levels and traffic density, providing empirical insights into the dynamics of transportation-driven air pollution in densely populated cities.
Methods: A quantitative cross-sectional study was conducted in July 2024, measuring CO concentrations at 15 strategic locations using calibrated CO meters. Sampling sites were selected based on traffic volume, population exposure, and historical emission data to ensure a comprehensive urban representation. Data analysis included descriptive statistics, normality tests, and regression analysis to evaluate relationships between CO levels, traffic patterns, and supporting variables.
Results: Findings revealed an average CO concentration of 6,665 µg/m³, with Jatinegara Kaum (15,380 µg/m³) and Duren Sawit (13,031 µg/m³) exceeding the government air quality threshold (10,000 µg/m³). A strong positive correlation (R² = 0.78, p < 0.05) was identified between traffic congestion and CO levels, confirming vehicular emissions as the dominant contributor. Moreover, no significant correlation with weather variables was observed, further emphasizing the role of transportation in shaping local air quality.
Conclusion: These results underscore the urgent need for policy interventions, including the expansion of electric vehicle infrastructure, congestion pricing, and green urban planning. This study also highlights the necessity of integrating real-time air quality monitoring and AI-based traffic flow management to optimize pollution control efforts. By situating East Jakarta’s case within global urban air pollution trends, these findings offer scalable insights applicable to other rapidly urbanizing cities worldwide.
Effects of Religious Instrumental Music Therapy on Pain Level in Breast Cancer Patients
Authors: Fujianti Mery Eka Yaya , Wahyuni Ida , Holis Willi
Published: February 2025

Introduction: Breast cancer is a type of cancer that frequently occurs in women, characterized by hard, movable lumps with an irregular shape. The main complaint in cancer patients is pain. Pain management can be performed through instrumental music therapy. Instrumental music therapy provides a relaxing effect due to the balanced tempo and harmony of tones.
Objective: This study aims to analyze the impact of religious instrumental music therapy on pain levels in breast cancer patients.
Method: This research is a quantitative study employing a quasi-experimental design, specifically utilizing a pre-test post-test control group design approach. This study's population is made up of 183 breast cancer patients. The research was conducted in the chemotherapy room of RSUD Dr. H. Moh. Anwar Sumenep from September to November 2022. The sampling technique used is non-probability sampling with a purposive sampling method, based on inclusion criteria. A total of 54 participants were selected and allocated to the intervention group and the control group. The McGill Pain Questionnaire (MPQ) is used to measure pain. Data analysis is performed using the Wilcoxon statistical test with a significance level of p<0.05. Data analysis is carried out using SPSS 24 software.
Result: The results of the bivariate test analysis showed that the pain level in the experimental group significantly changed before and after receiving the religious instrumental music therapy intervention, with a p-value < 0.05. In contrast, the control group showed no significant change, with a p-value of 1.000, as no intervention was provided.
Conclusion: Religious instrumental music therapy has proven to be effective in reducing pain levels in breast cancer patients at RSUD Dr. H. Moh. Anwar Sumenep.
Innovations in Artificial Rearing and Mass Production of Beneficial Insects for Biocontrol: A Review
Authors: Hurali Sujay , Narwade D. K. , Guntupalli Sravanthi , Sarangi Satyabrata , Babu Soumya Bharati , Pandey Adesh , Thodusu Mamatha , Patel Rupendra
Published: February 2025

The mass production and artificial rearing of beneficial insects have emerged as essential strategies in biological control, offering sustainable alternatives to chemical pesticides in integrated pest management (IPM). The recent innovations in insect mass rearing, focusing on advancements in artificial diet formulations, genetic improvements, automation, and precision agriculture technologies. Traditional rearing methods have faced challenges related to high costs, genetic variability, pathogen contamination, and reduced field performance of artificially reared insects. Cutting-edge biotechnological tools such as CRISPR-Cas9, RNA interference (RNAi), and microbiome engineering have enhanced insect adaptability, resistance to environmental stress, and reproductive efficiency. The implementation of artificial intelligence (AI) and robotics in mass-rearing facilities has optimized environmental conditions, reduced labour costs, and improved quality control. Climate-controlled rearing chambers and sustainable diet formulations incorporating nanotechnology and microencapsulation have significantly enhanced insect fitness, longevity, and field efficacy. The integration of mass-reared beneficial insects with precision agriculture techniques, including drone-assisted releases and GIS-based monitoring, has further increased efficiency and target-specific pest suppression. Despite these advancements, challenges remain, particularly concerning economic viability, regulatory constraints, and ethical considerations associated with large-scale insect production and field release. To address these issues, future research should focus on refining artificial rearing techniques, developing cost-effective rearing systems, and improving genetic diversity in captive insect populations. Strengthening international regulatory frameworks and adopting sustainable mass production practices will be key to the long-term success of biocontrol programs. The potential of artificial rearing technologies to revolutionize pest management, reduce reliance on chemical pesticides, and promote ecological conservation, reinforcing the role of biological control as a cornerstone of modern sustainable agriculture.