bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Situation and the Challenge of Eliminating Hepatitis B in Sub-Saharan Africa
Authors: Li Minxing , Ou Aiyue , Xiao Zhuoran
Published: May 2023

Chronic hepatitis B (CHB) belongs to chronic inflammatory disease. It is primarily transmitted through blood, mother to child, and sexual contact. In clinical practice, it is necessary to improve the examination as soon as possible. Only by early treatment can people delay and control the development of the disease and stabilize the disease. Otherwise, it will cause cirrhosis and lead to complications, such as ascites, bleeding, liver cancer, and so on. Antiviral therapy is the first choice for chronic hepatitis B virus infection. There are many drugs related to antiviral treatment in clinics, and different drugs have different effects. Vaccination can reduce the occurrence of diseases to a certain extent. However, despite hepatitis B having very effective vaccinations and excellent vaccinations available, there are still lots of patients that with the chronic hepatitis B in the sub-Saharan Africa. Due to the low HBV birth rate and limited resources in the sub-Saharan Africa, an effective and trustworthy strategy need to be built to achieve the goal of HBV elimination in sub-Saharan Africa. This article analyzes the current situation of prevention of the hepatitis B in the sub-Saharan region, and puts forward some intervention and prevention measures in order to provide some theoretical basis for the prevention and treatment of hepatitis B.
The long-term impact from colonialism to the public health behaviour and healthcare utilization in Cameroon
Authors: Wang Zhiyuan
Published: May 2023

The management of public health has always been a very important content in every country, such as curbing the development of HIV or AIDS related diseases is an important link in promoting the healthy development of global health. However, there are still many deficiencies, especially under the influence of colonial culture. This study exploits the long-term effect of partition by two different colony authorities with using regression discontinuity design when the British and the French administrations divided the German Cameroon into their colony in 1919. Results indicated that the individuals knowledge level for preventing HIV/AIDS from the side of French is lower than the British side from 0.3% to 6%, the knowledge of avoiding injections is 4% higher from the side of French compared to the other side, and the refuse rate to take a blood test for HIV/AIDS from the French Cameroon is higher than the British side about 2.2%. This research argues that the effect from the force injection and ineffective treatment during the medical campaign in Cameroon has persisted through its impacts on mistrust of western medical services. Hence, clusters on the French side which exposed by the largest medical campaign had lower knowledge about preventing HIV/AIDS, more awareness against injections, and less trust in the medical services.
Research on Environmental Factors and Lifestyles Related to the Prevalence of Infectious Diseases
Authors: Chu Yinglu
Published: May 2023

In recent years, several infectious diseases like COVID-19 and Monkeypox have been spreading worldwide, causing varying levels of panic. This paper explores the development of these diseases against the environmental factors for the population that they are living in, and if a persons living lifestyle is associated with the prevalence and cumulative incidence of these infectious diseases, for example, the relationship with other epidemiological diseases (diabetes and cardiovascular disease, whereas the risk for a person having diabetes is higher than the population without the certain diseases). This paper provides a broad overview of information related to environmental factors and living lifestyles associated with infectious disease prevalence and cumulative incidence by reviewing and collating some data on industrialization and ecosystem, and peoples living lifestyles related to exercise and nutrition. Based on data from past periods of high virus prevalence, polluted environments and bad habits may lead to a higher risk of being infected diseases.
Fexinidazole, A Promising Oral Treatment against Human African Trypanosomiasis, Clinical Research, and Potential
Authors: Huang Jinxiang , Liu Longyue , Wang Junyue
Published: May 2023

HAT, a parasitic disease that has significant impact on human nervous system, has caused several epidemic in sub-Sahara area. Between 1960-1990, approximately 5 HAT epidemic broke out in these areas. HAT can be aggressively communicable and vital without any treatment with a death rate of 95%. In addition, only little symptoms showed after infection so many patients who are not conscious about it may cause even more severe epidemic. In recent years, roughly 300 patients still die for it yearly. To cope with the disease, several medical companies make efforts to seek for treatments effectively against HAT. These research on treatment can prevent the wide spread of HAT and help patients to come back to their normal lives. The life expectancy and quality will also improve with treatment for HAT. Therefore, in this review, we collect information and data about HAT and relevant treatment. Among treatments, we focus on a recent drug named Fexinidazole, which can be effective to treat all phases of HAT. Furthermore, it also has potential to guide a new approach in finding new drugs by research on its mechanism.
Development of Vyvgart (Efgartigimod Alfa-Fcab) for Generalized Myasthenia Gravis (gMG) Therapy
Authors: Li Sirui
Published: May 2023

Generalized myasthenia gravis (gMG) is a type of myasthenia gravis (MG), a relatively rare neurological disease which would lead to muscle weakness and be life threatening. The pathogenesis of MG is associated with antibodies against acetylcholine receptors, which blocks the neuromuscular transmission. Vyvgart (efgartigimod alfa-fcab) is a recently approved drug for gMG therapy that targets the neonatal Fc receptor (FcRn). By inhibiting the interaction between FcRn and Immunoglobulin G (IgG), efgartigimod promotes the degradation of IgG and autoantibodies, therefore alleviates the symptoms of gMG. Antibodies against the acetylcholine receptor (AChR), muscle-specific kinase (MuSK) or low- density lipoprotein receptor related protein 4 in the postsynaptic muscle membrane would lead to the blocking of the receptors, and block the movement of muscle. Vyvgart (efgartigimod alfa-fcab) is a promising drug, this article contains a brief introduction to the pathogenesis of MG, information about the identification of FcRn as an effective target, and the development as well as advantages of Vyvgart.
Application of nanomaterials for drug delivery
Authors: Zhu Yiwei
Published: May 2023

One of the most important trends in recent years has been the use of nanomaterials for drug delivery. Drug treatment and application have been considerably aided by drug delivery techniques. The relentless search of cutting-edge delivery systems and methods is essential to the quick development of the medication therapy profession. The development of nanomedicines, or drug-delivery particles of 1-100 nm in size manufactured from medications and excipients, is the result of the fusion of nanotechnology and pharmacy. The primary drug delivery techniques currently in use, the nanomaterials that can be used, and the actual applications of nano-delivery are briefly discussed in this research. The topic of this research is increasing the likelihood and precision of multi-armed bandit attacks. The purpose of this research is to improve understanding of the nanodrug delivery framework. The prevailing trends in the area of drug delivery is further analyzed, where several researches have demonstrated that nanomaterials are one of the good options for drug delivery. The reported research shows several applications of drug delivery in different research areas to demonstrate that nano-delivery holds good promise for use and development. In addition, this research helps one to understand, review and enhance the basic application and development framework of nanodrug delivery
Heart Disease Diagnosis Associated with Potential Causative Factors Based on the 2020 Data
Authors: Wang Ruiyu
Published: May 2023

Heart disease is one of the leading causes of death all over the world. In order to determine the relationships between heart disease and some potential causing factors, this paper conducted the data analysis based on the survey results from the Centres for Disease Control and Prevention (CDC). By analyzing the correlation index and p-index, the author defined the general health condition, age, and background disease as the potential causative causing factors. At the same time, a logic regression model is applied to explore the relationship between them. It could be found as a result that with age increasing, people will face a higher risk of suffering from heart disease. Also, unhealthy daily life habits (i.e., smoking) would also increase the risk of heart disease. Furthermore, background diseases such as diabetics could also be a potential causative factor.
Research on the Importance and Methods of Core Strength Training for Track and Field Athletes
Authors: Deng Boyu
Published: May 2023

Nowadays, more and more people do not pay attention to core training when exercising, and only pay attention to the training of large muscle groups and anaerobic endurance training. Core training is actually one of the most important aspects of training. Therefore, this study explores the importance and methods of core strength training for track and field athletes. From reading the literature, this study found that core strength plays an important role in athletic performance. Using different core strength training methods can give us different core training effects.
Application of Different Spectral Methods for Target Analysis
Authors: Fu Yue , Zhang Jinghan , Zhen Shi , Zheng Yuhaohua
Published: May 2023

Spectral analysis methods are widely used for the analysis of different targets such as viruses, bacteria, heavy metals and their harmful substances due to their simplicity and efficiency. Among these spectral analysis methods, the study of luminescence and light absorption of different substances has important theoretical and practical significance. Atoms are different and emit different bright-line spectra, and the atoms of each element have a certain bright-line spectrum. Therefore, a diverse of different spectroscopic techniques can be used to achieve various target detection. In this research, four common spectral analysis methods are introduced, including Raman spectroscopic analysis, electroluminescence analysis, fluorescence analysis and colorimetric analysis. And this research analyzes the detection effect of these four spectral analysis methods on different targets, such as virus and pathogens. With the features of scientific type spectroscopic instruments or systems with high sensitivity, high resolution, high reliability and multidimensional information in spectroscopic techniques, the developed spectroscopic techniques to detect viruses effectively. And the demand for its application will be more urgent and will surely become a direction of great interest for quite a long time to come.
The Role of Traditional Chinese Medicine in the Treatment of COVID-19 Patient
Authors: Wang Qianyu
Published: May 2023

COVID-19 pandemic, caused by SARS-CoV-2, was the most serious pandemic which strongly impacted peoples daily life. During the three years that it has swept the world, it has caused severe and huge losses to the economies of various countries. resulting in tens of thousands of deaths. At present, the virus is still raging, threatening global human health. Patients showed symptoms similar to people with colds or fevers. As it becomes more and more serious, many scientists found that Traditional Chinese Medicine (TCM) has effects to cure the disease, particularly in the management of fevers and colds. This implies that TCM might be useful in the management of COVID-19 disease. Scientists did experiments on TCM which concluded the fact that TCM indeed is a way to treat COVID-19. TCM can alleviate COVID-19 symptoms by increasing CD4+/CD8+ ratio and recovering damaged body tissues. COVID-19 infected patients who are getting better after they received TCM treatments. The aim of this paper is to introduce the ways of why TCM plays an important role in treating SARS-CoV-2 virus.
A Neuromuscular Electrotherapy Device Based on Arduino System
Authors: Sun Cheng
Published: May 2023

One form of electrophysiological therapy, low frequency impulse electrotherapy, makes use of electrical impulses of very low voltage and frequency. The low frequency impulsed current affects the skin's outer layer, causing an electrolytic effect and a powerful stimulation of nerves, which in turn activates the nerves, improves local blood circulation, and, most importantly, provides analgesia. The frequency, time, waveform, and duty cycle of the electrical pulse have a significant impact on the efficacy of low frequency impulse therapy. The design is built on an Arduino UNO development board, with five additional buttons and LED beads for display. Electrotherapy impulses of varying frequencies and duty ratios can be generated by pushing the correct button, and the device can be preconfigured to provide high, medium, or low levels of stimulation. Then, two amplifier circuits send the electrotherapy impulses to two electrodes that are placed on the skin's surface.
The Clinical Application of Bispecific Antibodies in Cancer Treatment
Authors: Wang Siyun
Published: May 2023

Bispecific antibody (bsAb) is a type of human-modified antibody which two or more sites are capable of binding two or more individual antigens. This dual specificity enables bsAbs to have superior application than the monoclonal antibodies as they can eliminate tumour cells via recruiting T cells and also the accessory immune cells in some cases, as well as can simultaneously block two different signalling pathways or different disease mediator. More than 30 technologies have been applied for the development of bsAbs based on heavy chains and light chains heterologous recombination. However, only three bsAbs have been approved and available on the market, whereas over 110 BsAbs are at different clinical or research stages. In this paper, different types of bsAbs will be elaborated as well as the clinical significance of the approved bsAbs.
Application of Hydrogel in Artificial Organs
Authors: Wu Xiongni
Published: May 2023

Hydrogels with excellent biological properties are highly suited for usage as bionic materials for artificial organs, which is crucial to the development of artificial organs. As a novel bionic material, hydrogel offers a wide range of medical applications. Recent advances in hydrogel research have led to a further refinement of the technology by fitting various hydrogels to various artificial organs in order to reach an optimal fit. Due to the vast array of medical uses, many evaluations choose to examine the development of hydrogels in the context of the biomedical field as a whole. However, the research in the refined medical area is equally worthy of consideration and summation. This paper provides a brief introduction to the necessary properties and preparation methods of hydrogel medical materials, highlights the application of hydrogel medical bionic materials in various artificial organs, and presents some challenges of the current hydrogel, offering new ideas and methods for the development of artificial organs in the future.
The Factors Associated with Parkinsons Disease and the Current Treatment on PD
Authors: Huang Changzheng
Published: May 2023

Parkinsons disease (PD) is neurodegenerative disease that occur in 1% of people in their sixth and subsequent decades. The classical of PD symptoms include of tremors, bradykinesia, muscle stiffness, and loss of balance, and are associated by the reduced function of degenerative neurons and intracellular accumulation of abnormal proteins. The exact causation of PD is unknown, with environmental and genetic factors showing relation to PD. Genetic mutations and environmental toxicants, such as pesticides, are related with an elevated incidence of PD, according to epidemiologic research. Several investigations carried in animal models confirmed this association. Currently no treatment can retard or halt the disease progression, including the most commonly used therapy which is the replenishment of striatal dopamine through oral administration. This do alleviate most of the symptoms, but it also introduces several side effects including dyskinesias. At present, gene therapy is not used in the treatment of PD; rather, it is only employed in disease trials. The non-disease modifying treatments have been showing encouraging results while the disease modifying treatments hold a greater potential.
The Impact of Jellyfish Population on Human Economy and Countermeasures
Authors: Deng Yihan
Published: May 2023

Global warming has brought huge changes to marine life. This essay analyses the direct and indirect factors that lead to changes in the number of jellyfish, and the impact of the increase in the number of jellyfish on humans. The direct cause of the impact on the jellyfish population is due to global warming, and human overfishing is an indirect factor leading to the increase in the jellyfish population. However, as a result of the development of coastal cities by humans, the living environment of some giant jellyfish has been destroyed which resulting in a decline in the number of giant jellyfish. The growth in the number of jellyfish has caused a huge expense on the human economy in beach recreation, fishing and aquaculture. Therefore, the government needs to take some targeted measures to prevent the increase in the number of jellyfish and planning to prevent ecosystem changes due to continued global warming. Global warming and human overfishing lead to imbalances in marine ecosystems. This essay hopes to find more solutions that to prevent jellyfish populations from continuing to increase which can protect marine ecosystems and sustain the human economy.
ALK, TIMP1, GALNT14, New Emergent Poor Prognosis Indicators for Patients in Early Stage or Grade of Lung Cancer
Authors: Suo Zhikang
Published: May 2023

Lung cancer is presently the deadliest cancer worldwide, which causes large quantities of deaths, estimated more than 1.8 million, globally every year. Meanwhile, the diagnosis and prognosis for the early-stage lung cancer patients is always absent even until recent years, which has led to the result that the patients are mostly diagnosed with lung cancer in advanced stage. The present study searches for biomarkers related to early stage diagnosis so as to help deal with this factual problem. After analyzing plenty of samples on Kpalan-Meier plotter websites, this research discovers that ALK, GALNT14, TIMP1 are negatively related with OS of lung cancer patients. Further stratified analysis reveals that three proteins can indicate poor prognosis in the patients who got adenocarcinoma and were in early stage or grade. In addition, the present study also finds that the three proteins can respectively work as prognosis factor among three different groups of patients divided by gender, smoking history, and whether receiving chemotherapy or not. Conclusively, this research have discovered three biomarkers which can be applied in diagnosis, prognosis and treatment in the patients with early stage or grade of lung cancer.
Role of Astrocytes in Epilepsy and Schizophrenia
Authors: Liang Jiaming
Published: May 2023

The dangers of epilepsy and schizophrenia are increasingly being noticed. Its economic burden, social harm and harm to patients cannot be ignored. However, little is known about the pathogenesis of psychiatric disorders. Relevant treatment is limited to symptomatic treatment. Research suggests astrocytes play a role in seizures and schizophrenia. In the occurrence and development of mental diseases such as epilepsy and schizophrenia, astrocytes cannot be ignored. The article introduces the current findings and theories on role and function of astrocytes, and their connection with epilepsy and schizophrenia. It describes the positive effects and negative effects of astrocytes and their basic mechanisms that are now believed. And those mechanisms include glutamate-glutamine cycle which is related to the synthesizing of gama-aminobutyric acid (GABA), blood brain barrier which is controlling the matter exchange between vessels and brain, several molecules and inflammatory factors effect on the channel expressing on the surface of astrocytes and other main paths that could contribute to neuronal disorders. The article also includes several chemicals and their effects on inhibiting astrocytes of isolated sample, from chliroquine, calmodulin-trifluoperazin, gamma globulin and anticardiolipin antibodies. Last, the present study on the relationship between epilepsy and schizophrenia is discussed.
Differences of Appearance, Life Cycle, Symptoms, Diagnose and Treatment Mmong Taenia Solium, Taenia Saginata and Taenia Asiatica
Authors: Yue Xintong , Zhu Yuda
Published: May 2023

Tapeworm belongs to the class Cestoda of the Platyhelminth phylum. In tapeworms, the Taenia solium, Taenia asiatica, Taenia saginata are tapeworm that can infect human and cause taeniasis or other diseases. This essay concludes the basic information of these three kinds of tapeworms including the appearance, life cycle, symptoms, diagnosis, and treatment. In each part it summarizes the similarities and differences among them. The appearance introduces the entire body and gravid proglottid. It compares the length and width in these three kinds of tapeworms, their competence of producing last proglottid, the differences in hooks and the differences in gravid proglottid, which shows general figures of these three kinds of tapeworms. The lifecycle introduces their location and the ways of infection by comparing the differences. In the part of symptoms, the Neurocysticercosis is highlighted and introduce most, and the human immune inhibition is added to complement how human body to confront with tapeworms. In the diagnosis part, microscopical examination, PCR and antibody tests are used to identify the tapeworms. The PCR especially shows the differences of nucleotide sequence and predicted amino acids in tapeworms. For treatment, the similarities and differences in the treatment for different tapeworms are the important contents. Pumpkin seeds and areca nut extract are Chinese medicine, and it shows great power to deworm tapeworms. This essay hopes to get a deeper understanding of tapeworm through the above introduction, so as to promote the prevention and control of tapeworms.
Kombucha Tea: Microorganisms Communities Composition, Active Metabolites, Health Functions and Fermentation
Authors: Yang Hui
Published: May 2023

As a tea drinking product, Kombucha is made from sugar, water and tea as raw materials and fermented by a variety of probiotics and contains diverse metabolites derived from active microorganisms. As kombucha contains a variety of microorganisms, active ingredients, and uses a fermentation process, it has a wide range of health care functions such as antioxidant, liver protection, cardiovascular and cerebrovascular, and anti-cancer, and thus has become the focus of people all over the world. As a result, in order to better exert the health as well as commercial value of kombucha tea product, it is necessary to carry out research on the diversity of microorganisms in kombucha, active substances types and functions, and their relationship with the fermentation process. In order to further improve the flavor and health functions of this tea product and lay a solid foundation for the industrial production of Kombucha from the theoretical level, this thesis will provide a comprehensive analysis and summary of the latest research on microbial communitys composition, active metabolites, health efficacy and fermentation process factors of kombucha tea.
Statistic Study of Relation between the Algal Blooms and Chemicals in Water Body
Authors: Yu Qiu
Published: May 2023

The global trend of the algal blooms is rising fast without any questions. This paper is to investigate whether we can predict the number of the algae in water body by the content of some common chemicals to avoid the algal blooms and, at the same time, use less time and costs. Step regression will be used to filter the independent variables, then use principal component analysis to get rid of multilinearity in the model and use ordinary least squares regression to fit the linear relationship between the principal components chosen and the number of algae. The results show that there is some relationship between the variables studied but not very strong. The R-squared values calculated are 2.86 for the row data and 3.58 for the test data. And the major influential factors are mxPH, mnO2 and PO4. In conclusion, we can use the model to briefly predict the trend of the algal blooms but cannot get the number accurately. However, the results do reveal to us that maximum pH value, minimum value of oxygen and average of orthophosphate indeed have some significant impacts on this kind of algae.
Clinical Management of Cerebral Aneurysms
Authors: Kuai Yunyu
Published: May 2023

A number of people die every year because of aneurysms. Wide range of researches have been conducted into aneurysms, particularly for brain aneurysms. Due to the serious consequences of intracranial haemorrhage, there have been many new treatments including medication and surgical approaches developed in recent years, but at the same time there is still much room for technological improvement. As research has progressed, researchers have discovered that aneurysms are inextricably linked to inflammation and have proposed a number of medications to treat this condition. However, medication can only control aneurysms to a limited extent and is usually used as an adjunct to surgical treatment. This article summarizes the treatment of different aneurysms, as well as the prospect of surgical intervention and its future perspectives.
A Protocol for Systematic Review and Meta-analysis of Dietary Calcium and Fracture
Authors: Yang Tong
Published: May 2023

Despite the fact that there are few and inconsistent randomized controlled studies investigating calcium obtained from food, calcium and vitamin D are frequently utilized as calcium supplements in people's daily lives, so the effectiveness of food-derived calcium and calcium or a combination of the two is in question. Through a review and qualitative research, this paper explores the connection between dietary calcium and fracture incidence. The link between dietary calcium, vitamin D, or combination dietary calcium and vitamin D supplements and fracture incidence in the elderly over 65 years of age was examined. Calcium intake was based on food sources.A comprehensive search of the PubMed database was conducted. Use the keywords dietary calcium, vitamin D, and fracture to search for relevant randomized controlled trials in English studies. Search the Cochrane Library and EMBASE databases to add additional randomized clinical trials. Data were extracted from papers independently by two reviewers and entered into data tables. By using Cochran's Q statistic and the I-2 statistic, it was possible to determine whether the rate estimates were heterogeneous. Hip fracture was the primary outcome and total fracture was the secondary outcome.
The Recent Advances of PARP Inhibitors in the Treatment of Cancer
Authors: Li Dongyue
Published: May 2023

This article introduces the discovery and research progress of Poly-ADP-ribose polymerases (PARP) inhibitors. The catalytic sites of PARP1 and PARP2 are designed as competitive inhibitors of NAD+, so that DNA single-strand repair cannot be completed through the combination of PARP1 and NAD+.PARP is quite crucial in the process of DNA single-strand damage repair. Inhibiting PARP function will interfere with normal DNA repair and induce DNA damage accumulation into more serious double-strand breaks through replication fork folding. Homologous recombination (HR) repair is the main way of double DNA repair, which needs to be mediated by key proteins BRCA1 and BRCA2. In the same way, blocking the single chain repair and HR pathway, the synergistic lethal effect produced by combining these two nonlethal mechanisms, namely the synthetic lethality mechanism, provides a theoretical basis for PARPi. Olaparib was approved for clinical by FDA for the first time through this mechanism. The efficacy of Olaparib in the four approved indications was confirmed in clinical trials. It can benefit patients by improving the progress-free survival or objective response rate, and its safety is better than chemotherapy drugs. Even more clinically valuable combination of platinum and chemotherapy drugs has been proven to benefit significantly. At last, the paper pointed out the development emphasis and prospect of PARP inhibitors in the future.
The Syntactic Variations in Adverb Phrase ‘As well’ in Initial Position in Pakistani English (PakE): A Corpus Based Study
Authors: Imran Muhammad
Published: May 2023

This study aims to pinpoint the variations in Adverb Phrase ‘As well’ in the initial position in PakE, and investigate the influence of the substrate linguistic effect of the Urdu language on PakE. For this study, a corpus GlowbE-PK was utilized. In total, 192 Adverb phrases in the initial position of the sentence were found. This study utilized the mixed method research and also kept in view the Sociolinguistic Variation and World Englishes conventions of research.The number and frequency of tokens per million words were calculated. Overall, PakE reveals a frequency of 3.84% per 1 million words. The results and discussions indicated a noticeable variation in the Adverb phrase of PakE from Standard BrE. This research also confirms the negative linguistic influence of the substrate language Urdu on Pakistani English in the use of the Adverb phrase 'As well', although the substrate language clearly shows the influence on many other features of PakE, as in Adjective phrase – the use of Double comparatives and superlatives. Furthermore, this research identifies the same feature Adverb phrase ‘as well’ in other varieties of English.
NURSE'S KNOWLEDGE LEVEL OF HANDLING EMERGENCY PATIENTS DUE TO TRAFFIC ACCIDENTS AT RSUD PARAPAT SIMALUNGUN REGENCY
Authors: Sondang Sidabutar  , Christian Rayando Butar Butar  , Diana Lorenta Barimbingan
Published: May 2023

Traffic accidents can cause loss of a person or disability as well as injuries that require immediate help, such as hard object trauma to the head which can cause nerve disorders, failure in an organ such as respiratory failure and kidney failure, loss of fluids and electrolytes in large quantities, bleeding, and trauma or injury to the musculoskeletal system. Hospitals as health care facilities that have health workers must be able to provide optimal health services, especially for patients who are in an emergency condition. Efforts to provide health services to emergency patients are basically able to prevent death or disability that may occur. A study was carried out on 32 respondents (nurses) which aimed to determine the level of knowledge of nurses about handling emergency patients due to traffic accidents at the Emergency Unit of Parapat General Hospital, where this research is descriptive in nature, and uses totally sampling (the whole population), namely totaling 32 people, and carried out using primary data obtained from distributing questionnaires. After data processing was carried out, it was found that the majority of respondents had sufficient knowledge, namely around 20 people (62,500%) and had good knowledge, around 6 people (18,750%), less knowledgeable, around 6 people (18,750%) based on the level of education, the majority of respondents had sufficient knowledge, namely around 20 people (62.500%) and good knowledge about 6 people (18.750%).
A CONCEPTUAL ANALYSIS OF THE DIFFICULTIES AND POTENTIAL HRM TECHNIQUES FOR THE INTERACTION OF MANPOWER WITH ARTIFICIAL INTELLIGENCE
Authors: Dr. Aajaz Ahmad Hajam  , Alphonsa S John
Published: May 2023

Abstract
 
 
Objective - This essay intends to particularly address the difficulties that modern organizations' human resource management (HRM) departments and leaders confront as a result of the close interaction between human workers and artificial intelligence (AI)—primarily robots—especially at the team level. On the basis of a conceptual evaluation of the available research, it also offers some prospective solutions that may be helpful to overcome these difficulties.
Design, methodology, and approach — To give a very comprehensive yet critical overview of the interaction between AI (especially robots) and HRM in modern organizations, the current study engages in conceptual work that integrates several streams of literature.
Results - We emphasize that interactions and teamwork between human workers and robots are evident across a variety of organizational tasks and industries, where both are contributing team members. The HRM function in modern organizations is faced with some particularly difficult challenges as a result of the need to address workers' anxiety about working with AI, particularly in relation to potential job loss and the challenging dynamics of establishing trust between human employees and AI-enabled robots as team members. Along with these, HRM staff members need to carefully handle employee performance evaluations in the future as well as human workers' expectations for task completion with their AI-enabled robot co-workers. When placing human workers in teams with robots, the authors discovered that organizational support mechanisms such as a welcoming climate, training opportunities, and assuring a suitable technological competence level are crucial. Finally, we discovered that one of HRM's most difficult difficulties is performance evaluation in teams where humans and AI (including robots) coexist. We emphasized the possibility of drawing insights from the computer gaming literature, where performance evaluation models have been developed to analyze human and AI interactions while keeping the context and limitations of both in mind. We discussed the lack of frameworks to guide HRM managers in this concern.
Originality/value - Our study is one of the few to go beyond a broad or functional analysis of AI in the context of human resource management. It focuses primarily on the teamwork aspect, where human employees and AI-powered robots (robots) collaborate and provide insights and suggestions for such teams' efficient operation.
NEW ECONOMIC POLICY IN 1991 AND CONSEQUENTLYVICISSITUDES IN TAMIL NADU
Authors: VENKATESH.R
Published: May 2023

Abstract

 Politics and economics are ambiguous regarding the progress of a society. The economy can be considered a measure of social progress. A sustainable society under a stable state will lead to the collapse of an unstable regime that will not make sustainable progress. The political and economic changes that took place in India in the 1990s led to many changes. Tamil Nadu is the state that has used those changes to its advantage. This study illustrates some of those changes.
THE INFLUENCE OF TEACHING MATERIALS DEVELOPMENT ON STUDENT UNDERSTANDING IN CLASS VII ISLAMIC RELIGIOUS EDUCATION SUBJECTS AT IT MIDDLE SCHOOL. AN-NAFIS TELUK MENGKUDU DISTRICT SERDANG BEDAGAI DISTRICT
Authors: Chairuddin Siregar  , Irdian Ningsih
Published: May 2023

This research uses a quantitative approach, where the symptoms are measured using numbers. The results of the research in this thesis, There is a significant positive relationship between the development of teaching materials on students' understanding of class VII Islamic Education subjects. This is evidenced by the results obtained, namely by using the product moment correlation formula, the correlation index value is obtained of 0.808 which ranges from 0.70 to 0.90, this means that there is a significant correlation between variable X and variable Y, namely a strong or high correlation. Then by examining the table of the value of "r" product moment, it turns out that with a df of 50 at the 5% significance level, the "r" table is 0.297, then at the 1% significance level the value is 0.361 . If we look at the number " Barriers to understanding students in class VII Islamic Education subjects are not entirely due to the development of teaching materials, but it is likely that these teaching materials have indeed become one of the factors that can affect the inhibition of student understanding. This is evidenced by 100% of the development of teaching materials in accordance with KI and KD. Barriers to understanding students in class VII Islamic Education subjects are not entirely due to the development of teaching materials, but it is likely that these teaching materials have indeed become one of the factors that can affect the inhibition of student understanding. This is evidenced by 100% of the development of teaching materials in accordance with KI and KD.
ANALYSIS OF THE IMPLEMENTATION OF QURAN RECITATIONS FOR MADRASAH STUDENTS TSANAWIYAH AL WASHLIYAH PAKAM VILLAGE MEDANG DERAS DISTRICT BATU BARA REGENCY
Authors: Muliatno  , Rio Ari Waldani
Published: May 2023

Type This research is a type of qualitative descriptive research.The results of the research in this thesis,Extracurricular implementationRecitations at Madrasah Tsanawiyah Al Washliyah Desa Pakam place more emphasis on theoretical and practical elements, this is compatibility in fostering the art of reading the Koran, meaning that it is appropriate when implemented or applied to the field of reading the Koran, that is, it will always implement and develop these strategies in order to further enhance student learning optimally . Based on the results of interviews with the head of the madrasa and the recitation extracurricular supervisor, there are inhibiting factors, namelylow student motivation, less gifted student problems, fales voice problems, lack of time for activities as well as, less varied learning methods. The implementation of recitations of the Koran at Madrasah Tsanawiyah Al Washliyah Pakam Village, Medang Deras District was held in the framework of introducing knowledge to students who lack mastery and as a trigger to deepen how to read the Koran properly and correctly. The recitation extracurricular at Madrasah Tsanawiyah Al Washliyah Desa Pakam was the idea of ​​the vice head of the madrasa namely. This activity was formed with the aim that the students of Madrasah Tsanawiyah Al Washliyah Pakam Village can read the Koran properly and correctly.
SECULARISM IN INDIA MYTH OR REALITY: AN EXPLANATORY STUDY
Authors: Yousuf Rather Aqib
Published: May 2023

An impetus was given to the discussion on whether or not Indian secularism is a myth or a reality. A secular society is one in which individuals are free to practise their religion of choice. The Constitution of India recognises and upholds the principle of religious toleration, making India a nation that is home to a number of distinct faiths. The term "secular" was not included in the original version of the Indian Constitution; nevertheless, it was added in 1976 as part of the 42nd Amendment. Nevertheless, the values of secular character have always been a part of the constitutional fabric of India, and this has been the case since the very beginning. The Judiciary has, on numerous occasions, drawn attention to this particular facet as well. It is possible to state with absolute certainty that secularism is one of the guiding principles of the Constitution and that this position will never be subject to revision. Nonetheless, there have been cases where the state has been seen to favour a specific religion over the concept of secularism. In order to better understand Indian secularism, we've written this piece. Secularism in India is described as a myth or reality and the issues related with it are discussed.
THE EFFECT OF PREDISPOSING, ENABLING AND REINFORCING ON EXCLUSIVE BREASTFEEDING
Authors: Risma Zul , Marniati Marniati , Nih Farisni Teungku , Fitriani Fitriani
Published: May 2023

Exclusive breastfeeding is breastfeeding only for infants 0-6 months without providing other food or drinks other than breast milk. The low coverage of exclusive breastfeeding indicates that there is a problem with exclusive breastfeeding in the working area of the Meutulang Health Center. This study aims to determine the effect of Predisposing (Knowledge, Attitude, Action) Enabling (Maternal Nutritional Status) and Reinforcing (Culture) on exclusive breastfeeding in the working area of the Meutulang Health Center. The research method is quantitative with a cross sectional study design. The population in this study were mothers who had babies of 6-12 months totaling 44. The sample of this study used the total sampling method. The data analysis technique used univariate and bivariate analysis with simple linear regression test. The results showed that partially there was an effect of knowledge variable (0.001 < 0.05), action variable (0.017 < 0.05), and cultural variable (0.000 < 0.05) on exclusive breastfeeding. However, the attitude variable (0.986>0.05) and the mother's nutritional status variable (0.934>0.05) had no effect on exclusive breastfeeding. The conclusion of the study is that there is an influence of knowledge, action, culture on exclusive breastfeeding and there is no influence of attitude, mother's nutritional status on exclusive breastfeeding. It is hoped that the puskesmas and related institutions will more often hold outreach and socialization to the community, especially mothers about the importance of exclusive breastfeeding for 6 months.
ANALYSIS OF DETERMINANTS OF NUTRITIONAL PARENTING PATTERNS FOR TODDLERS IN TEUPIN PANAH VILLAGE, DISTRICT. KAWAY XVI, WEST ACEH REGENCY
Authors: Arung Natasya Aprilia , Fitriani Fitriani
Published: May 2023

Nutritionary of children rearing is a factor that is intimately related the aggrandizement and exploitation of children underneath five-spot second childhood of age. The amplitude of children superannuated 6-59 months (toddlers) is a amplitude when children all the more in reality pauperization chop chop and nutrition in adequate and correspondent quantities. This contemplate directs to psychoanalyse the constituents that consequence nutritionary of children rearing in under-fives in IndonesiaTeupin Panah Village, Kaway XVI District, Kab. westbound Aceh. The disposition euphemistic pre-owned in this contemplate is a qualitative drawing near usingstudyfield (field research). This contemplate put into practice a qualitative drawing near which is a disposition euphemistic pre-owned to resolution evaluation predicaments accompanying to collections in the configuration of descriptions sourced from press conference observations, and extracting documents. supported on the consequences carried elsewhere in the field, the diligence of correspondent nutrition of children rearing in the community of Teupin pointer is all the more low, this is outstanding to the little consciousness of formal progenitrix approximately nutritionary of children rearing patterns, little incompatible breastfeeding for toddlers, not all the more well-defined in gift MP ASI to children, and refreshment settings. few diversification of food. supported on these findings, the investigator buoy resolve that consciousness of maternalistic nutrition and nutritionary of children rearing conspicuously pressures the nutritionary prominence of children underneath five.
CONFIRMATORY FACTOR ANALYSIS ON THE LEGAL ASPECTS OF BUSINESS FUNDING WITH SECURITIES CROWDFUNDING SCHEME ON SMEs IN MEDAN MUNICIPAL CITY
Authors: Hafidz Nasution M.Y.F. , Nasution M. Pintor , Gultom Pardomuan
Published: May 2023

SMEs is one of the important pillars in the national economic development who to date, are still faced with its classical issue in obtaining additional capital funding. The securities crowdfunding concept that was introduced to be the solution for SMEs is yet to reach the 64,2 million SMEs in Indonesia due to SMEs’ difficulties in complying to the regulatory requirements. Therefore, the objective of this research is to analyze the legal factors that may affect SMEs’ interests in obtaining capital funding via the securities crowdfunding concept. This research is conducted by using quantitative approach and analyzed by using the confirmatory factor analysis and descriptive analysis methods based on the primary data collected from 50 SMEs in BPC HIPMI Medan on a purposive sampling basis. Based on the research findings, the implementation of the disclosure principle in POJK 57/2020 are mainly the cause of SMEs’ inability and affecting interests in the securities crowdfunding concept. Therefore, further development of POJK 57/2020 as the regulatory basis of the securities crowdfunding concept are essential in supporting SMEs’ exponential growth in the future.
UTILIZATION OF LATRINE AND SEPTIC TANK CONTSTRUCTION BY THE DEPARTEMENT OF PUBLIC WORKS AND SPATIAL PLANNING SERVICE IN THE NUMBER OF OPEN DEFECATION IN THE VILLAGE OF DRIEN MANGKO, DISTRICTS WEST ACEH
Authors: Kasum Umi , Musnadi Is Jun
Published: May 2023

Sanitation predicaments are all the more a characteristic disputed point encountered in indefinite territories and places, individual of which is in Drien Mangko Village, Woyla District, westbound Aceh rule in 2021, videlicet ODF administer defecation, thither are 62. in good health latrine sanitation has totality aggrandizement to everlasting in good health latrines JSP 29. 9%, semi-permanent in good health latrines JSSP 3 and all the more doing distribution (ride) 3. constituents causing ODF are little commensurate of economical capacity, general public are unqualified to satisfy becoming sanitation development. To bowled over this disputed point the westbound Aceh universal drudgeries and Spatial provisioning accommodation enforced a sanitation exploitation announcement in the community of Drien Mangko. The evaluation disposition put into practice a descriptive qualitative classification by conducting press conference approximately the discription of knowledge, dispositions and performances as advantageously as examinations on the superiority of latrines and abscessed tanks. The totality inhabitant is the beneficiaries in the configuration of Toilet washable and abscessed coolhead consisting of 9 families. The objective is to ascertain approximately the discription of the application of toilets and abscessed tanks that chalk up been reinforced by the universal drudgeries and Spatial provisioning occupation of westbound Aceh in 2021. The consequences established that 55. 6% chalk up first-class knowledge, 22. 2% chalk up adequate consciousness and deprivation of knowledge. 100% of respondents who chalk up a first-class attitude. 100% of respondents who chalk up first-class actions. The consequences of the examination that the interpretation of toilets and abscessed tanks is in conformation with wellness criteria with reference to in good health kith and kin latrines that buoy accommodate wellness requirements. The determination from the consequences is that respondents buoy application latrines and abscessed tanks advantageously so that the universal drudgeries and spatial provisioning division succeeded in reduction the ODF character in Drien Mangko community in 2022 nailed down the latrine and abscessed coolhead interpretation program.