bluuebunny/crossref_metadata_2025 huggingface dataset:
Status and Trends in Financial Inclusion and Financial Stability: A Comparative Analysis of SAARC Countries
Authors: B M Sajjad Hossain  , Nasrin Akhter  , Md. Taufiqul Islam  , Md. Abul Hasam
Published: July 2022

Financial Inclusion (FI) refers to the process of bringing more people under the coverage of formal financial sector/s. It is very common in developed countries over the decades. But with the development of science and technology, financial inclusion has been introduced and spread in many developing nations in recent times. Most of the South Asian Association for Regional Cooperation (SAARC) nations are still under the category of developing economies. Mostly financial inclusion has taken part in this region for the last two decades. This research conducted a comparative study among the different SAARC nations based on the achievement in financial inclusion. This paper attempted to identify the sequential position of those countries as they can evaluate them by comparing each other for further improvement and stability.
The impact of video recording in EFL oral production tasks with college students
Authors: Cárdenas Sánchez Silvia Elizabeth , Moyota Amaguaya Patricia Pilar , Gallegos Núñez María Mercedes
Published: July 2022

Introducción: Las tareas de grabación de vídeo se han adaptado para practicar las habilidades productivas orales en inglés. Este tipo de tareas ha permitido que los alumnos tengan más oportunidades de desarrollar sus habilidades orales mientras aprenden inglés. Las destrezas lingüísticas productivas, como la expresión oral, son tan importantes como las demás, ya que ayudan a comunicar ideas en diferentes contextos. Objetivo: Conocer el punto de vista de los estudiantes sobre el uso de tareas grabadas en vídeo como complemento de la práctica del idioma. Metodología: Este estudio se diseñó para Los estudiantes universitarios de los niveles A1 y A2 realizaron cinco tareas durante el periodo académico de octubre de 2021 a marzo de 2022. En este estudio participaron 74 personas. Al final del periodo académico, los estudiantes respondieron a un cuestionario cuyo objetivo era obtener información sobre su percepción de la creación de videos grabados en lugar de tareas escritas. Resultados: Los resultados de la encuesta demostraron que existe una actitud positiva hacia el uso de esta estrategia. Conclusiones: Los participantes concluyeron que las grabaciones de vídeo les ayudaban a practicar más la pronunciación y a mejorar su vocabulario.
Experiencia y práctica comunitaria: valorización del Kichwa en los estudiantes del sexto y séptimo año de Educación Básica
Authors: Paqui Abrigo Mayra Verónica , García Herrera Darwin Gabriel , Guevara Vizcaíno Claudio Fernando
Published: July 2022

La presente investigación se puntualiza en cómo la práctica comunitaria y familiar promueve la valorización del idioma kichwa en los estudiantes de Sexto y Séptimo año de Educación Básica del Centro Educativo Comunitario Ángel María Ávila Quizhpe de la comunidad de Gurudel del cantón Saraguro, provincia de Loja, para dar respuesta a la pregunta de investigación se diseña un modelo de metodología con enfoque mixto en el que se combina técnicas de investigación, métodos y leguaje de investigación cuantitativo y cualitativo. Los resultados indican que la comunidad a pesar de que cumple un rol indispensable en la práctica de valores y respeto a la identidad no se visualiza en su convivir diario es decir los padres y madres de familia no practican con sus hijos en el hogar el kichwa. En conclusión, se puede afirmar que con los métodos y técnicas aplicadas se detecta que la mayor parte de las familias consideran al español como su idioma materno, a pesar de mostrar su interés en recuperar el idioma oficial y entender el verdadero significado del kichwa como una herencia que dejaron los antepasados, quienes lucharon para que la comunidad indígena no continúe siendo marginados ni maltratados.
Educomunicación y rescate de la gastronomía Shuar
Authors: Orellana Cuji Rosa Marina , Apolo Buenaño Diego Eduardo , Cabrera Berrezueta Luis Bolívar
Published: July 2022

El campo de la gastronomía es demasiado amplio y cuando se habla de rescate de tradiciones que se van perdiendo con el paso del tiempo, y la falta de atención de la juventud, se deben implementar estrategias de Educomunicación para incentivar a los jóvenes a conocer estas tradiciones y promover el turismo. . El objetivo de este trabajo es promover la gastronomía Shuar a través de la Educomunicación, utilizando metodología cualitativa, con un enfoque descriptivo y exploratorio, y utilizada como herramienta de recolección de información a partir de encuestas, obteniendo resultados favorables para la implementación de la Educomunicación para promover el turismo manteniendo la tradición de la gastronomía Shuar. Concluyendo que el proyecto de investigación abordó todos los objetivos mencionados y cumplió con una propuesta innovadora para la comunidad de Santa Rosa de Mamanguy, ubicada en la provincia de Morona Santiago, Ecuador.
Deskripsi Pemahaman Konsep Matematika dalam Menyelesaikan Soal Fungsi Komposisi Siswa Kelas X SMAN 11 Pinrang
Authors: Bahar Erni Ekafitria , Syahri Andi Alim
Published: July 2022

Penelitian ini bertujuan untuk mendeskripsikan pemahaman konsep dalam menyelesaikan soal fungsi komposisi siswa kelas X SMAN 11 Pinrang yang terdiri dari tiga indikator yaitu menyatakan ulang sebuah konsep, memberi contoh dan bukan contoh, menerapkan konsep dalam pemecahan masalah. Penelitian ini merupakan penelitian kualitatif yang dapat dijadikan acuan adalah siswa SMAN 11 Pinrang untuk mengetahui pemahaman konsepnya dalam menyelesaikan soal fungsi kompsisi. Teknik pengumpulan data yang digunakan adalah pemberian tes dan wawancara. Tes bertujuan untuk memperoleh gambaran mengenai pemahaman konsep subjek mengenai materi tersebut sedangkan wawancara bertujuan untuk menguatkan hasil tes pemahaman konsep dalam menyelesaikan soal fungsi komposisi. Hasil penelitian menunjukkan: (1) Pemahaman konsep subjek tinggi dalam menyelesaikan soal fungsi komposisi yaitu: (a) kemampuan dalam menyatakan ulang konsep cukup baik karena subjek mampu membedakan makna  dan  namun subjek lupa syarat dua buah fungsi dapat dikomposisikan; (b) kemampuan memberikan contoh dan non contoh dari konsep termasuk baik karena subjek mampu memberikan contoh dua buah fungsi yang jika dikomposisikan maka  = ; (c) kemampuan subjek menerapkan konsep dalam pemecahan masalah temasuk kategori baik; (2) Pemahaman konsep subjek sedang dalam menyelesaikan soal fungsi komposisi yaitu: (a) kemampuan menyatakan ulang konsep termasuk kategori baik karena subjek mampu membedakan makna  dan  dan menyebutkan syarat dua buah fungsi dapat dikomposisikan; (b) kemampuan memberikan contoh dan bukan contoh kurang baik karena subjek belum mampu memberikan contoh dua buah fungsi yang tidak dapat dikomposisikaan; (c) kemampuan subjek menerapkan konsep dalam pemecahan masalah temasuk kategori cukup baik.
Pengaruh penggunaan media video pembelajaran melalui pendekatan scientific terhadap hasil belajar matematika siswa
Authors: Angraeni Reni , Husniati Andi , Gaffar Abdul , Mustapa. R Zulfahmi
Published: July 2022

Absrak. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian Pre-Eksperimental Designs. Desain penelitian yang digunakan One-Group Pretest-Posttest Design, populasi dan sampel dalam penelitian ini adalah kelas XI SMA Negeri 4 Bantaeng yang berjumlah 22 siswa pada tahun ajaran 2021/2022. Pengumpulan data yang digunakan adalah tes dan observasi. Data dianalisis dengan menggunakan analisis statistik deskriptif dan analisis statistik inferensial. Pengaruh Penggunaan Media Video Pembelajaran Melalui Pendekatan Scientific dalam proses pembelajaran diketahui pula berdasarkan hasil perhitungan uji-t. Hasil penelitian ini diperoleh:  dan  maka  lebih besar dari pada  sehingga dinyatakan bahwa ada pengaruh yang signifikan terhadap penggunaan media video pembelajaran melalui pendekatan scientific terhadap hasil belajar murid pada mata pelajaran matematika di kelas XI MIPA SMA Negeri 4 Bantaeng, artinya penggunaan media video pembelajaran melalui pendekatan scientific ini memberikan pengaruh positif yang signifikan.Kata Kunci: Hasil Belajar, Media Video, Pendekatan Scientific.
Pola Barisan Aritmatika pada Ketukan Irama Gending Lancaran dalam Kesenian Alat Musik Gamelan Tembung Dolanan
Authors: Falah M. Fajrul , Marhayati Marhayati , Fa'ani Arini Mayan
Published: July 2022

Penelitian ini bertujuan untuk mendeskripsikan eksplorasi pola barisan bilangan aritmatika pada ketukan irama gending lancaran dalam kesenian alat musik gamelan Tembung Dolanan studi kasus pada Gending Gugur Gunung. Jenis penelitian ini kualitatif dengan pendekatan etnografi. Data yang disajikan dalam penelitian merupakan hasil dari wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa pada Gending Lancaran yang dimainkan dengan alat musik gamelan memiliki suatu konsep matematika yaitu pola barisan aritmetika yang terdapat di setiap ketukan pada Tembung Dolanan. Hasil penelitian menunjukkan bahwa dalam ketukan nada yang dipukul dengan alat musik Kethuk, Kempul, Kenong, dan Bonang Babok memuat pola barisan aritmatika. Bentuk umum pola barisan aritmatika dalam ketukan atau pukulan dari alat musik Kethuk yaitu mn= 2n - 1.  Bentuk umum pola barisan aritmatika dalam ketukan atau pukulan alat musik Kempul yaitu mn = 4n + 2. Bentuk umum pola barisan aritmatika dalam ketukan atau pukulan dari alat musik Kenong yaitu mn = 4n. Bentuk umum pola barisan aritmatika dalam ketukan atau pukulan dari alat musik Bonang Babok yaitu mn= 4n.
Pengaruh locus of control terhadap penalaran matematis siswa
Authors: La Kalamu La Yusran , Djafar Hariyanti
Published: July 2022

Salah satu kemampuan yang diharapkan dimiliki siswa dalam kegiatan pembelajaran matematika adalah penalaran. Penalaran dapat membantu siswa dalam mengambil sebuah kesimpulan dari permasalahan yang dihadapi. Berdasarkan nilai UAS di salah satu sekolah (SMA N 8 Tidore Kepulauan, banyak siswa yang belum memenuhi KKM. Didukung oleh hasil keterangan guru di sekolah tersebut bahwa sebagian besar siswa mengalami kesulitan belajar matematika, tidak mampu membuat manipulasi matematika, keliru dalam menyimpulkan masalah matematika. Selain itu, sebagian siswa belum memiliki keyakinan untuk dapat menyelesaikan tugas yang diberikan guru, hal ini dapat dilihat ketika guru menunjuk siswa tertentu untuk menyelesaikan soal di depan kelas, namun siswa tersebut menunjuk teman lain untuk mengerjakan soal tersebut. Tujuan penelitian ini adalah mengetahui pengaruh langsung locus of control terhadap penalaran matematis siswa kelas XI SMA/SMK se-Kecamatan Oba Utara. Tempat Penelitian ini adalah SMA/SMK se-Kecamatan Oba Utara. Waktu Penelitian dilaksanakan selama 3 bulan yakni bulan Agustus s.d bulan November 2021, dimulai dari persiapan penelitian sampai pada tahap publikasi jurnal ilmiah. Jenis penelitian ini adalah penelitian survey kausal. Populasi penelitian ini adalah seluruh siswa SMA/SMK se-Kecamatan Oba Utara yang berjumlah 763 orang, diperoleh sampel sebanyak 88 orang dengan menggunakan teknik purposive sampling. Teknik pengumpulan data yang digunakan adalah metode tes dan angket. Analisis data yang digunakan adalah analisis deskriptif, uji persyaratan dan uji hipotesis yang meliputi analisis regresi linier. Hasil penelitian menunjukan bahwa locus of control berpengaruh langsung secara positif dan signifikan terhadap penalaran matematis siswa SMA/SMK se-Kecamatan Oba Utara Kota Tidore Kepulauan. Dengan demikian dapat disimpulkan bahwa semakin baik locus of control seseorang semakin tinggi kemampuan penalaran matematisnya.Kata Kunci: Penalaran Matematis, Locus of Control, Siswa SMA/SMK.
BERPIKIR KRITIS MATEMATIK
Authors: Abdullah In Hi
Published: July 2022

Artikel ini membahas tentang salah satu kemampuan berpikir tingkat tinggi dalam bidang matematika, yaitu berpikir kritis matematik. Berpikir matematik diartikan sebagai aktivitas mental dalam melaksanakan proses matematika (doing math)  atau tugas matematika (mathematical task). Kemampuan berpikir matematik mencakup: pemahaman konsep (conceptual understanding), pemecahan masalah (problem solving), penalaran dan pembuktian (reasoning and proof), komunikasi (communication), koneksi (connection)  dan representasi (representation). Berpikir kritis adalah aktivitas mental yang dilakukan menggunakan langkah-langkah dalam metode ilmiah, yaitu: memahami dan merumuskan masalah, mengumpulkan dan menganalisis informasi yang diperlukan dan dapat dipercaya, merumuskan praduga dan hipotesis, menguji hipotesis secara logis, mengambil kesimpulan secara hati-hati, melakukan evaluasi dan memutuskan sesuatu yang akan diyakini atau sesuatu yang akan dilakukan, serta  meramalkan konsekuensi yang mungkin terjadi. Dengan demikian, berpikir kritis matematis adalah aktivitas mental dalam bidang matematika yang dilakukan  menggunakan langkah-langkah metode ilmiah.
EFEKTIVITAS PENERAPAN METODE DRILL DALAM PEMBELAJARAN MATEMATIKA SISWA KELAS X SMKN 2 WATAMPONE
Authors: Sirwanti Sirwanti
Published: July 2022

Penelitian ini merupakan penelitian eksperimen yang bertujuan untuk mengetahui keefektifan metode Drill terhadap hasil belajar matematika siswa kelas X SMKN 2 Watampone.Sampel dalam penelitian ini adalah satu kelas yaitu X TSM dengan jumlah 27 orang siswa.Analisis statistic yang digunakan adalah analisis deskriptif dan inferensial. Hasil analisis deskriptif diperoleh nilai rata-rata pretest sebesar 35,48 yang berada pada kategori kurang dengan simpangan baku 7,403, nilai rata-rata  posttest sebesar 80,33 yang berada pada kategori baik dengan simpangan baku 10,061, peningkatan hasil belajar matematika siswa dari pretest ke posttest sebesar 0,695 yang berada pada kategori sedang, Rata-rata aktivitas siswa sebesar 85,521 yang berada pada kategori aktif,  rata-rata respon siswa sebesar 81,106 yang berada pada kategori positif dan rata-rata keterlaksanaan siswa sebesar 96,875 yang berada pada kategori sangat baik. Hasil analisis deskriptif ini diperkuat juga oleh analisis inferensial dengan statistic uji t. Berdasarkan analisis data tersebut dapat disimpulkan bahwa metode Drill efektif terhadap hasil belajar matematika siswa. Kata kunci: efektivitas, hasil belajar matematika, metode pembelajaran Drill
Pengaruh Minat dan Kedisiplinan Siswa dengan Gaya Kognitif Field Indefendent terhadap Hasil Belajar Matematika Siswa SMK Farmasi Yamasi Makassar
Authors: Jainuddin Jainuddin , Salim S Soma , Sirajuddin Sirajuddin
Published: July 2022

Tujuan dari penelitian ini adalah untuk mengetahui bagaiamana minat belajar dan kedisiplinan siswa dengan gaya kognitif field indefendent terhadap hasil belajar matematika siswa kelas X SMK Farmasi Yamasi Makassar.Penentuan sampel adalah dari seluruh siswa kelas X diberikan tes gaya kognitf Group  Embedded Figures Test (GEFT), dan didapatkan hasil sebanyak 35 orang bergaya kognitif fiekd indefendnt. Metode yang digunakan adalah kuantitatif deskriptif. Dalam menganalisa data digunakan softwere IBM SPSS versi 25 for Windows. Analisis meliputi uji validitas dan uji relibilitas untuk angket minat dan kedisiplinan. Selanjutnya dilakuka uji prasyarat meliputi a) Uji Normalitas, b) Uji Linearitas, c) Uji Multikolinearitas serta . uji hipotesis yaitu analisis regresi ganda. Pada uji hipotesis didapatkan nilai sig untuk minat belajar dan kedisiplinan dengan taraf signifikan 5% (0,05) yaitu 0.000 < 0,05 artinya minat belajar dan kedisiplinan berpengaruh terhadap hasil belajar matematika siswa dengan gaya kognitif field indefendent pada kelas X SMK Farmasi Yamasi Makassar. Besar pengaruhnya yaitu 53,9%, selebihnya dipengaruhi oleh faktor lain. Kesimpulan penelitian ini yaitu minat belajar dan kedisiplinan berpengaruh terhadap hasil belajar matematika siswa dengan gaya kognitif field indefendent pada kelas X SMK Farmasi Yamasi Makassar.Kata Kunci: Field Indefendent, Minat Belajar, Kedisiplinan
Gerakan Literasi Matematika dalam Peningkatan Kemampuan Pemecahan Masalah Matematis Siswa
Authors: Zahroh Halimatus , Hafidah Hafidah , Dhofir Dhofir , Zayyadi Moh
Published: July 2022

Literasi telah menjadi perbincangan hangat dalam dunia internasional dan menjadi harapan besar dunia.Berbagai pihak gencar melakukan penilaian literasi dan berusaha mencari cara untuk meningkatkan literasi di berbagai negara. Begitu juga di Indonesia, pemerintah telah menyadari bahwa untuk menghadapi dunia yang semakin kompleks diperlukan generasi muda yang tanggap dan kritis. Dunia pendidikan matematika pun tidak ingin ketinggalan dalam meningkatkan dan mengembangkan kemampuan literasi matematika siswa. PISA (Program for International Student Assessment) adalah penilaian tiga tahunan bagi siswa yang berusia 15 tahun yang mendekati akhir belajarnya di seluruh dunia dengan tujuan untuk menilai pengetahuan dan keterampilan siswa yang meliputi literasi matematika, literasi sains dan literasi membaca sebagai seorang generasi yang dapat bersaing penuh dan ikut berpartisipasi dalam dunia globalisasi dan masyarakat modern, dengan fokus penilaiannya bukan tentang apa yang siswa ketahui, melainkan apa yang bisa mereka lakukan dengan yang  mereka ketahui.Literasi matematika dapat diartikan sebagai kemampuan setiap individu untuk merumuskan, menafsirkan, menalar, menginterpretasikan, mengkomunikasikan, dan menjelaskan pemecahan masalah dalam kehidupan sehari-hari secara efektif dan efisien.
Use of a Rigid-Tipped Microguidewire for the Endovascular Treatment of Cavernous Sinus Dural Arteriovenous Fistulas with an Occluded Inferior Petrosal Sinus
Authors: Deniwar Mohamed Adel , Kwon Boseong , Song Yunsun , Park Jung Cheol , Lee Deok Hee
Published: July 2022

Objective : Transvenous embolization (TVE) via an occluded inferior petrosal sinus (IPS) in a cavernous sinus dural arteriovenous fistula (CSDAVF) is challenging, often requiring navigation of a microcatheter through resistive obstacles between the occluded IPS and shunted pouch (SP), although the reopening technique was successfully performed. We report five cases of successful access to the cavernous sinus (CS) or SP using the rigid-tipped microguidewire such as chronic total occlusion (CTO) wire aiming to share our initial experience with this wire.Methods : In this retrospective study, four patients with CSDAVF underwent five procedures using the CTO wire puncture during transfemoral transvenous coil embolization. Puncture success, shunt occlusion, and complications including any hemorrhage and cranial nerve palsy were evaluated.Results : Despite successful access through the occluded IPS, further entry into the target area using neurointerventional devices was impossible due to a short-segment stricture before the CS (three cases) and a membranous barrier within the CS (two cases). However, puncturing these structures using the rigid-tipped microguidewire was successful in all cases. We could advance the microcatheter over the rigid-tipped microguidewire for the navigation to the SP and achieved complete occlusion of the SP without complications.Conclusion : The use of the rigid-tipped microguidewire in the TVE via the occluded IPS of the CSDAVF would be feasible and safe.
Uluslararası Hukuk ve Türk Hukuku Açısından Göçmen Kaçakçılığı Suçunda “Maddi Menfaat Elde Etme Amacı” Kavramı
Authors: YAŞAR Yusuf , GÜNEŞ Umut
Published: July 2022

Sınıraşan Örgütlü Suçlara Karşı Birleşmiş Milletler Sözleşmesine Ek Kara, Deniz ve Hava Yoluyla Göçmen Kaçakçılığına Karşı Protokol, her taraf ülkeye göçmen kaçakçılığını suç haline getirme yükümlülüğünü getirmiştir.

Protokole göre göçmen kaçakçılığı ancak “dolaylı ya doğrudan mali ya da diğer maddi menfaat elde etme amacıyla” yapıldığında oluşmaktadır. Bu tanıma karşın bazı ülkeler göçmenlere maddi menfaat beklentisi olmadan yapılan yardımları dahi suç haline getirmişlerdir.

Çalışmamızın amacı Göçmen Kaçakçılığı Protokolünün göçmen kaçakçılığını nasıl tanımladığını açıklamak ve bazı Avrupa ülkeleri ile Türkiye’nin “dolaylı ya doğrudan mali ya da diğer maddi menfaat elde etme amacı”nı yasalarına nasıl yansıttıklarını incelemektir.
Uluslararası İnsancıl Hukukun Zamansal Kapsamı (II): “Uluslararası Olmayan Silahlı Çatışmalarda” İnsancıl Hukukun Uygulanmaya Başlaması
Authors: GÜR Hande , SARIBEYOĞLU SKALAR Meltem
Published: July 2022

Uluslararası insancıl hukukun zamansal kapsamını saptamak bu kuralların çatışma süresince uygulanabilmesi açısından son derece önemlidir. Uluslararası olmayan silahlı çatışmalara ilişkin uluslararası insancıl hukuk kurallarının uygulanmaya başlama anının belirlenmesi, uluslararası silahlı çatışmalara ilişkin olarak belirlenmesinden çok daha zordur. Çünkü bir devletin ülkesi içinde meydana gelen şiddet durumunun uluslararası olmayan silahlı çatışma olarak sınıflandırılması ve uluslararası insancıl hukuk kurallarının bu çatışmalara ne zaman uygulanmaya başlayacağı konusu yoruma açıktır. Zira iç karışıklık ancak belli bir eşiğe ulaştığında uluslararası insancıl hukuk kuralları bu çatışmalara uygulanacağından, bunun tespiti her zaman kolay olmamaktadır. Bu makalede uluslararası nitelikte olmayan silahlı çatışmalara yönelik uluslararası insancıl hukuk kurallarının uygulanabilmesi açısından uluslararası olmayan silahlı çatışmanın başlangıç anının tespit edilmesi amaçlanmaktadır.
Eseri Çoğaltma Hakkının Cezai Himayesi ve Şahsen Kullanma Meselesi
Authors: ÖZDEMİR Süleyman Emre
Published: July 2022

Telif hakları ve bu hakların korunma seviyesi, ülkelerin gelişmişlik göstergeleri arasında yer almaktadır. Hukukumuzda, 5846 sayılı Fikir ve Sanat Eserleri Kanunu (FSEK)’nda, telif haklarının hukuki himayesinin yanı sıra cezai himayesi de öngörülmüştür. Öte yandan telif hakları, sahibine fikri çabalarının sonucu olarak ortaya çıkan çalışmaları için verilen bir ödüllendirme ve teşvik aracı olmanın yanı sıra toplumun da bu çalışmalardan fayda sağlamasına imkân veren, iki tarafın çıkarları arasında denge kurmayı amaçlayan bir sistem üzerine inşa edilmiştir. Dolayısıyla FSEK’te teklif haklarını sınırlayan çeşitli hükümlere de yer verilmiştir. Bunlardan biri FSEK’in 38’inci maddesinde düzenlenen ve hukuka uygunluk sebebi teşkil eden şahsen kullanmadır. Şahsen kullanma esasen eser sahibinin çoğaltma hakkının sınırlandırılmasına ilişkin olup mali haklara tecavüz suçu ve özelinde eseri çoğaltma hakkının cezai himayesi bakımından hususiyet arz etmektedir. Çalışmamızda öncelikle eseri çoğaltma hakkının cezai himayesi üzerinde durulacak olup ardından bir hukuka uygunluk sebebi olarak şahsen kullanma meselesi incelenecektir.
Perancangan Hazard Identification Risk Assessment And Risk Control (HIRARC) Dan Implementasi Solusi Pada Stasiun Kerja Lubang Kancing PT. Bintang Permata Sejati
Authors: Setiawan Niko , Kartika Novenda
Published: July 2022

PT. Bintang Permata Sejati merupakan perusahaan yang bergerak dibidang garmen. Kondisi pabrik yang terjadi adalah 11 kali kecelakaan kerja pada stasiun lubang kancing dalam periode 5 bulan. Kecelakaan kerja berakibat pada penghentian sementara proses produksi yang mengakibatkan lembur. Biaya yang harus ditanggung perusahaan selama 5 bulan sebesar Rp. 44.055.000,- meliputi biaya lembur dan rumah sakit. Tidak terdapat upaya yang dapat menangani kecelakaan karena pabrik tidak melakukan manajemen kesehatan dan keselamatan kerja. Perancangan HIRARC bertujuan untuk menganalisis dan mengatasi masalah. Hasil dari analisis berupa upaya yang diterapkan. Perancangan HIRARC terbagi menjadi 3 tahap. Tahap pertama adalah identifikasi bahaya (hazard identification, tahap kedua adalah penilaian risiko (risk assement), dan tahap ketiga adalah pengendalian risiko (risk control). Hasil dari perancangan HIRARC adalah solusi. Solusi berupa upaya yang diterapkan langsung ke pabrik garmen. Hasil dari identifikasi masalah pada stasiun kerja lubang kancing menghasilkan 17 sumber masalah yang berasal dari faktor manusia, material, metode, mesin, dan lingkungan. Penilaian risiko meliputi low, medium, dan high risk didapatkan hasil 8 masalah pada low risk, 3 masalah pada medium risk, dan 6 masalah pada high risk. Masalah diatasi dengan 5 upaya yang dilakukan yaitu penggunaan sarung tangan besi, isolasi lakban, kabel tie, memanfaatkan waktu istirahat dan penukaran kursi. Upaya yang diterapkan memiliki biaya sebesar Rp. 1.620.000,-. Biaya untuk upaya jauh lebih rendah dibandingkan dengan keuntungan yang didapat. Dokumen HIRARC harus terus menerus dibarui agar relevan tiap waktu dan perlu adanya penelitian lanjutan mengenai tingkat efektivitas upaya.
Optimalisasi Pekerjaan Jembatan Utama PT.Wijaya Karya Proyek Lanjutan Aksesibilitas Bandara Soekarno Hatta di Masa Pandemi Covid-19 Tahun 2020-2021
Authors: Ismiarso Jessica Clarista , Putrianto Novenda Kartika
Published: July 2022

Pembangunan Aksesibilitas Bandara Soekarno Hatta-Tangerang mengalami penundaan waktu pengerjaan, khususnya pada pembangunan jembatan utama yang menjadi inti pembangunan.Penundaan pekerjaan disebabkan oleh adanya pandemi covid-19. Untuk mengatasi bertambahnya penundaan waktu pengerjaan, dilakukan optimalisasi pekerjaan. Pekerjaan jembatan utama yang dioptimalisasi adalah periode dari bulan Februari 2019 hingga November 2021. Akibat adanya keterlambatan dari pekerjaan proyek, pihak owner memiliki permintaan untuk dilakukan percepatan hingga bulan Mei 2021 (118 minggu). Metode yang digunakan adalah Critical Path Method (CPM) untuk menentukan durasi dan lintasan kritis, serta metode project crashing untuk menentukan percepatan durasi dan perhitungan biaya durasi. Oleh sebab itu, terdapat dua alternatif optimalisasi yang dapat digunakan yaitu alternatif penambahan jam kerja (lembur) serta alternatif shift kerja. Hasil penelitian menunjukkan, kedua alternatif tersebut dapat melakukan crashing dalam waktu 118 minggu. Namun terdapat perbedaan terhadap direct cost tersebut, dimana dengan menggunakan alternatif penambahan kerja, membutuhkan penambahan biaya sebesar Rp 1,455,346,223.78 sedangkan dengan menggunakan alternatif shift kerja penambahan biaya nya sebesar Rp 1,562,626,223.78. Disisi lain, nilai dari indirect cost adalah sama karena durasi crashing sama, serta direct cost mengalami kenaikan karena perhitungan crashing berada pada perhitungan waktu dan pekerja yang berada di lapangan. Oleh sebab itu optimalisasi pekerjaan jembatan utama dengan menggunakan alternatif penambahan jam kerjaadalah alternatif yang sesuai dengan permintaan owner, karena perhitungan biaya serta durasi yang sesuai dengan perhitungan owner.
Trophic ecology of an abundant kelp forest echinoderm, the bat star Patiria miniata
Authors: Cryan DM , Low NHN , Litvin SY , Osenberg CW , Micheli F
Published: July 2022

Echinoderms often play key roles in structuring marine ecosystems. The bat star Patiria miniata is an abundant echinoderm in the kelp forests of the northeastern Pacific coast whose trophic ecology has been understudied. Understanding the trophic role of P. miniata is important given the recent declines of many sea star populations due to wasting disease. Patiria miniata was largely unaffected by these outbreaks and could potentially fill the trophic niches left by other ecologically important sea star species. In this study, we used a combination of feeding experiments and stable isotope analysis to provide new insights into the trophic ecology of P. miniata. Given that P. miniata is considered an omnivorous generalist, we conducted a series of feeding experiments in which we quantified consumption rates for a wide range of reported prey items. Consumption rates were highest for different types of carrion, lower for sessile invertebrates, and negligible for all species of macrophytes. In a series of follow-up experiments, we found that food deprivation did not lead to demonstrable consumption of macrophytes by P. miniata, but that the presence of epiphytes significantly increased consumption rates (presumably of the epiphytes plus incidental consumption of macrophytes). Finally, we compared the isotopic niche of P. miniata with that of a carnivore (the giant sea star Pisaster giganteus), an herbivore (the purple sea urchin Strongylocentrotus purpuratus), and a detritivore (the warty sea cucumber Parastichopus parvimensis) and found that P. miniata occupied the highest relative trophic level and was isotopically most similar to P. giganteus. Altogether, our results suggest that the diet of P. miniata is narrower and more carnivorous than previously expected.
Hello, world! VIVA+: A human body model lineup to evaluate sex-differences in crash protection
Authors: John Jobin , Klug Corina , Kranjec Matej , Svenning Erik , Iraeus Johan
Published: July 2022

Finite element Human Body Models are increasingly becoming vital tools for injury assessment and are expected to play an important role in virtual vehicle safety testing. With the aim of realizing models to study sex-differences seen in the injury- and fatality-risks from epidemiology, we developed models that represent an average female and an average male. The models were developed with an objective to allow tissue-based skeletal injury assessment, and thus non-skeletal organs and joints were defined with simplified characterizations to enhance computational efficiency and robustness. The model lineup comprises female and male representations of (seated) vehicle occupants and (standing) vulnerable road users, enabling the safety assessment of broader segments of the road user population. In addition, a new workflow utilized in the model development is presented. In this workflow, one model (the seated female) served as the base model while all the other models were generated as closely-linked derivative models, differing only in terms of node coordinates and mass distribution. This approach opens new possibilities to develop and maintain further models as part of the model lineup, representing different types of road users to reflect the ongoing transitions in mobility patterns (like bicyclists and e-scooter users). In this paper, we evaluate the kinetic and kinematic responses of the occupant and standing models to blunt impacts, mainly on the torso, in different directions (front, lateral, and back). The front and lateral impacts to the thorax showed responses comparable to the experiments, while the back impact varied with the location of impact (T1 and T8). Abdomen bar impact showed a stiffer load-deflection response at higher intrusions beyond 40 mm, because of simplified representation of internal organs. The lateral shoulder impact responses were also slightly stiffer, presumably from the simplified shoulder joint definition. This paper is the first in a series describing the development and validation of the new Human Body Model lineup, VIVA+. With the inclusion of an average-sized female model as a standard model in the lineup, we seek to foster an equitable injury evaluation in future virtual safety assessments.
Low Molecular Weight Sericin Enhances the In Vitro of Immunological Modulation and Cell Migration
Authors: Cherng Juin-Hong , Chang Shu-Jen , Chiu Yaw-Kwan , Chiu Yu-Hsiang , Fang Tong-Jing , Chen Hsiang-Cheng
Published: July 2022

Sericin, a waste product of the silk textile industry, has favorable physicochemical and biological properties. In this study, we extracted a low molecular weight (MW) sericin (LMW-sericin; below 10 kDa) by a performing high-temperature and high-pressure method and confirmed the MW using matrix-assisted laser desorption ionization-time of flight and liquid chromatography–mass spectrometry. Furthermore, we determined its biological effects on macrophages and human adipose stem cells (hASCs) as cell models to investigate the biocompatibility, immunomodulation behavior, and potential signaling pathway-related wound healing via analyses of gene expression of focal adhesion and human cytokines and chemokines using quantitative real-time polymerase chain reaction and cytokine assay. LMW-sericin showed good biocompatibility both in macrophages and hASCs. Macrophages cultured with 0.1 mg/ml LMW-sericin displayed an improved inflammatory response shown by the upregulation of CXCL9, IL12A, BMP7, and IL10, which developed Th1 and Th2 balance. LMW-sericin also improved the differentiation of macrophages toward the M2 phenotype by significantly enhancing the expression of Arg-1, which is conducive to the repair of the inflammatory environment. Moreover, the gene expression of hASCs showed that LMW-sericin promoted the secretion of beneficial adhesion molecules that potentially activate the gene transcription of differentiation and migration in hASCs, as well as significantly enhanced the levels of PKCβ1, RhoA, and RasGFR1 as fruitful molecules in wound healing. These findings provide insights into LMW-sericin application as a potential biomaterial for wound management.
Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models
Authors: Koutras Christos , Shayestehpour Hamed , Pérez Jesús , Wong Christian , Rasmussen John , Tournier Maxime , Nesme Matthieu , Otaduy Miguel A.
Published: July 2022

The use of patient-specific biomechanical models offers many opportunities in the treatment of adolescent idiopathic scoliosis, such as the design of personalized braces. The first step in the development of these patient-specific models is to fit the geometry of the torso skeleton to the patient’s anatomy. However, existing methods rely on high-quality imaging data. The exposure to radiation of these methods limits their applicability for regular monitoring of patients. We present a method to fit personalized models of the torso skeleton that takes as input biplanar low-dose radiographs. The method morphs a template to fit annotated points on visible portions of the spine, and it relies on a default biomechanical model of the torso for regularization and robust fitting of hardly visible parts of the torso skeleton, such as the rib cage. The proposed method provides an accurate and robust solution to obtain personalized models of the torso skeleton, which can be adopted as part of regular management of scoliosis patients. We have evaluated the method on ten young patients who participated in our study. We have analyzed and compared clinical metrics on the spine and the full torso skeleton, and we have found that the accuracy of the method is at least comparable to other methods that require more demanding imaging methods, while it offers superior robustness to artifacts such as interpenetration of ribs. Normal-dose X-rays were available for one of the patients, and for the other nine we acquired low-dose X-rays, allowing us to validate that the accuracy of the method persisted under less invasive imaging modalities.
Natural polymer-based scaffolds for soft tissue repair
Authors: Chen Meiwen , Jiang Rui , Deng Niping , Zhao Xiumin , Li Xiangjuan , Guo Chengchen
Published: July 2022

Soft tissues such as skin, muscle, and tendon are easily damaged due to injury from physical activity and pathological lesions. For soft tissue repair and regeneration, biomaterials are often used to build scaffolds with appropriate structures and tailored functionalities that can support cell growth and new tissue formation. Among all types of scaffolds, natural polymer-based scaffolds attract much attention due to their excellent biocompatibility and tunable mechanical properties. In this comprehensive mini-review, we summarize recent progress on natural polymer-based scaffolds for soft tissue repair, focusing on clinical translations and materials design. Furthermore, the limitations and challenges, such as unsatisfied mechanical properties and unfavorable biological responses, are discussed to advance the development of novel scaffolds for soft tissue repair and regeneration toward clinical translation.
Advances and trends in microbial production of polyhydroxyalkanoates and their building blocks
Authors: Gao Qiang , Yang Hao , Wang Chi , Xie Xin-Ying , Liu Kai-Xuan , Lin Ying , Han Shuang-Yan , Zhu Mingjun , Neureiter Markus , Lin Yina , Ye Jian-Wen
Published: July 2022

With the rapid development of synthetic biology, a variety of biopolymers can be obtained by recombinant microorganisms. Polyhydroxyalkanoates (PHA) is one of the most popular one with promising material properties, such as biodegradability and biocompatibility against the petrol-based plastics. This study reviews the recent studies focusing on the microbial synthesis of PHA, including chassis engineering, pathways engineering for various substrates utilization and PHA monomer synthesis, and PHA synthase modification. In particular, advances in metabolic engineering of dominant workhorses, for example Halomonas, Ralstonia eutropha, Escherichia coli and Pseudomonas, with outstanding PHA accumulation capability, were summarized and discussed, providing a full landscape of diverse PHA biosynthesis. Meanwhile, we also introduced the recent efforts focusing on structural analysis and mutagenesis of PHA synthase, which significantly determines the polymerization activity of varied monomer structures and PHA molecular weight. Besides, perspectives and solutions were thus proposed for achieving scale-up PHA of low cost with customized material property in the coming future.
The Polarized Redistribution of the Contractile Vacuole to the Rear of the Cell is Critical for Streaming and is Regulated by PI(4,5)P2-Mediated Exocytosis
Authors: Fadil Sana A. , Janetopoulos Chris
Published: July 2022

Dictyostelium discoideum amoebae align in a head to tail manner during the process of streaming during fruiting body formation. The chemoattractant cAMP is the chemoattractant regulating cell migration during this process and is released from the rear of cells. The process by which this cAMP release occurs has eluded investigators for many decades, but new findings suggest that this release can occur through expulsion during contractile vacuole (CV) ejection. The CV is an organelle that performs several functions inside the cell including the regulation of osmolarity, and discharges its content via exocytosis. The CV localizes to the rear of the cell and appears to be part of the polarity network, with the localization under the influence of the plasma membrane (PM) lipids, including the phosphoinositides (PIs), among those is PI(4,5)P2, the most abundant PI on the PM. Research on D. discoideum and neutrophils have shown that PI(4,5)P2 is enriched at the rear of migrating cells. In several systems, it has been shown that the essential regulator of exocytosis is through the exocyst complex, mediated in part by PI(4,5)P2-binding. This review features the role of the CV complex in D. discoideum signaling with a focus on the role of PI(4,5)P2 in regulating CV exocytosis and localization. Many of the regulators of these processes are conserved during evolution, so the mechanisms controlling exocytosis and membrane trafficking in D. discoideum and mammalian cells will be discussed, highlighting their important functions in membrane trafficking and signaling in health and disease.
High-Resolution Decadal Drought Predictions for German Water Boards: A Case Study for the Wupper Catchment
Authors: Paxian Andreas , Reinhardt Katja , Pankatz Klaus , Pasternack Alexander , Lorza-Villegas Maria Paula , Scheibel Marc , Hoff Amelie , Mannig Birgit , Lorenz Philip , Früh Barbara
Published: July 2022

Water boards in Germany require decadal predictions to develop optimized management and adaptation strategies, especially within the claims of flood protection and water distribution management. Specifically, the Wupper catchment water board in western Germany is interested in decadal predictions of drought indices, which are correlated to dam water levels. For the management of small catchments, they need multi-year means and multi-year seasonal means of the hydrological seasons for forecast years 1–3 at high spatial resolution. Thus, the MPI-ESM-LR global decadal prediction system with 16 ensemble members at 200 km resolution was statistically downscaled with EPISODES to ~11 km in Germany. Simulated precipitation was recalibrated, correcting model errors and adjusting the ensemble spread. We tested different recalibration settings to optimize the skill. The 3-year mean and 3-year seasonal mean SPI (Standardized Precipitation Index), indicating excess or deficit of precipitation, was calculated. We evaluated the prediction skill with HYRAS observations, applying skill scores and correlation coefficients, and tested the significance of the skill at a 95% levelvia1,000 bootstraps. We found that the high-resolution statistical downscaling is able to preserve the skill of the global decadal predictions and that the recalibration can clearly improve the precipitation skill in Germany. Multi-year annual and August–October mean SPI predictions are promising for several regions in Germany. Additionally, there is potential for skill improvement with increasing ensemble size for all temporal aggregations, except for November–January. A user-oriented product sheet was developed and published on the Copernicus Climate Change Service website (https://climate.copernicus.eu/decadal-predictions-infrastructure). It provides 3-year mean probabilistic SPI predictions for the Wupper catchment and north-western Germany. For 2021–2023, a high probability of negative SPI (dry conditions) is predicted in most of the area. The decadal prediction skill is higher than using the observed climatology as reference prediction in several parts of the area. This case study was developed in cooperation with the Wupper catchment water board and discussed with further German water managers: The skill of high-resolution decadal drought predictions is considered to be promising to fulfill their needs. The product sheet is understandable, well-structured and can be applied to their working routines.
Multimodal Coherence Revisited: Notes on the Move From Theory to Data in Annotating Print Advertisements
Authors: Stöckl Hartmut , Pflaeging Jana
Published: July 2022

The present paper proposes a preliminary annotation framework for the study of multimodal coherence in print ads. The framework is firmly based on a review of current theorizing on multimodal cohesion and coherence. Following guidelines for good empirical practice, the annotation scheme is tested on 50 ad samples, seeking to illustrate genre-specific qualities of multimodal coherence and to identify difficulties in applying conceptual frameworks to data. The paper employs six dimensions of multimodal coherence: layout, cohesive ties, info-linking, relational propositions, mode-centricity and multimodal rhetorical operations. In conclusion, we outline some of the more general challenges that multimodal annotation raises when it makes close contact with data.
Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition
Authors: Osuru Hari Prasad , Lavallee Matthew , Thiele Robert H.
Published: July 2022

Introduction

Oxidative phosphorylation is an essential feature of Animalian life. Multiple adaptations have developed to protect against hypoxia, including hypoxia-inducible-factors (HIFs). The major role of HIFs may be in protecting against oxidative stress, not the preservation of high-energy phosphates. The precise mechanism(s) of HIF protection is not completely understood.

Materials and Methods

To better understand the role of hypoxia-inducible-factor-1, we exposed heart/myocardium cells (H9c2) to both normoxia and hypoxia, as well as cobalt chloride (prolyl hydroxylase inhibitor), echniomycin (HIF inhibitor), A2P (anti-oxidant), and small interfering RNA to beclin-1. We measured cell viability, intracellular calcium and adenosine triphosphate, NADP/NADPH ratios, total intracellular reactive oxidative species levels, and markers of oxidative and antioxidant levels measured.

Results

Hypoxia (1%) leads to increased intracellular Ca2+ levels, and this response was inhibited by A2P and echinomycin (ECM). Exposure of H9c2 cells to hypoxia also led to an increase in both mRNA and protein expression for Cav 1.2 and Cav 1.3. Exposure of H9c2 cells to hypoxia led to a decrease in intracellular ATP levels and a sharp reduction in total ROS, SOD, and CAT levels. The impact of hypoxia on ROS was reversed with HIF-1 inhibition through ECM. Exposure of H9c2 cells to hypoxia led to an increase in Hif1a, VEGF and EPO protein expression, as well as a decrease in mitochondrial DNA. Both A2P and ECM attenuated this response to varying degrees.

Conclusion

Hypoxia leads to increased intracellular Ca2+, and inhibition of HIF-1 attenuates the increase in intracellular Ca2+ that occurs with hypoxia. HIF-1 expression leads to decreased adenosine triphosphate levels, but the role of HIF-1 on the production of reactive oxidative species remains uncertain. Anti-oxidants decrease HIF-1 expression in the setting of hypoxia and attenuate the increase in Ca2+ that occurs during hypoxia (with no effect during normoxia). Beclin-1 appears to drive autophagy in the setting of hypoxia (through ATG5) but not in normoxia. Additionally, Beclin-1 is a powerful driver of reactive oxidative species production and plays a role in ATP production. HIF-1 inhibition does not affect autophagy in the setting of hypoxia, suggesting that there are other drivers of autophagy that impact beclin-1.
Understanding Study Drug Discontinuation Through EUCLID
Authors: Weissler E. Hope , Mulder Hillary , Rockhold Frank W. , Baumgartner Iris , Norgren Lars , Blomster Juuso , Katona Brian G. , Fowkes F. Gerry R. , Mahaffey Kenneth , Bonaca Marc , Patel Manesh R. , Jones W. Schuyler
Published: July 2022

Introduction

Disparities in the care and outcomes of peripheral artery disease (PAD) have been well-established. In part this is due to disparities in enrollment of PAD trial cohorts. However, less attention has been paid to non-random protocol non-adherence after enrollment, which may lead to inaccurate estimates of treatment effects and reduce generalizability of study results. We aimed to ascertain characteristics associated with premature study drug discontinuation in a PAD cohort.

Methods

Using data from EUCLID (Examining Use of Ticagrelor in Peripheral Artery Disease), factors associated with study drug discontinuation were assessed using univariable and multivariable Cox proportional hazards models with time to study drug discontinuation as the outcome of interest. Relationships between study drug discontinuation and major adverse cardiovascular events (MACE; cardiovascular death, myocardial infarction, ischemic stroke), major adverse limb events (MALE; acute limb ischemia, major amputation, and lower extremity revascularization), and all-cause hospitalization were assessed.

Results

Of 13,842 eligible EUCLID participants, 3,886 (28.1%) prematurely and permanently discontinued study drug over a maximum follow-up of 42 months (annualized rate of 13.2 discontinuations per 100 patient-years). In a multivariable model, premature study drug discontinuation was associated with older age (aHR 1.16, 95%CI 1.14–1.19), eligibility based on prior lower extremity revascularization rather than ABI/TBI criteria (aHR 1.14, 95%CI 1.06–1.23), CLI status (aHR 1.23, 95%CI 1.06–1.42), COPD (aHR 1.36, 95%CI 1.24–1.49), and geographic region. In a multivariable analysis, study drug discontinuation was significantly associated with MACE (aHR 3.27, 95%CI 2.90–3.67, p < 0.001), MALE (aHR 1.84, 95%CI 1.63–2.07, p < 0.001), and all-cause hospitalization (aHR 2.37, 95%CI 2.21–2.54) following study drug discontinuation.

Conclusions

This analysis of EUCLID demonstrates that premature, permanent discontinuation of study drug is relatively common in more than a quarter of PAD patients, is unevenly distributed based on geography and other baseline characteristics, and is associated with worse outcomes in a clinical trial context. Study teams leading future PAD trials may want to address the possibility of study drug discontinuation prospectively, as a proactive approach may help investigators to maintain study cohort diversity and representativeness without sacrificing power and precision.