bluuebunny/crossref_metadata_2025 huggingface dataset:
Longitudinal mechanics as predictors of left ventricular systolic function in the early postoperative period after surgical perimembranous ventricular septal defect closure in children aged <1 year
Authors: Sinelnikov Yu. , Orekhova E. , Matanovskaya T.
Published: July 2019

Aim. To evaluate left ventricular systolic function in the early postoperative period after surgical perimembranous ventricular septal defect (VSD) closure in children aged <1 year using longitudinal mechanics.Methods. Between 2014 and 2017, we examined 65 children aged 2–11 months with perimembranous VSD (mean diameter = 8.6 ± 1.7 mm) and a pulmonary-to-systemic blood flow ratio of >1.5/1. The longitudinal mechanics of the left ventricle (LV) were assessed using vector velocity imaging. All the children underwent surgical perimembranous VSD closure. Echocardiographic studies were performed preoperatively, immediately postoperatively, and 1 and 20 days postoperatively.Results. In all the children, significant decreases in the LV end-systolic volume index, end-diastolic volume index, stroke volume index (SVI), and ejection fraction (EF) were identified immediately postoperatively when compared with the preoperative findings. One day postoperatively, the LV volume data normalized; however, in 10.8% of the children, the SVI and EF remained impaired. The percentage EF reduction showed weak correlations with the childrens’ weights (Rs = 0.3; p = 0.039), aortic cross-clamping durations (Rs = 0.36; p = 0.03), and VSD sizes (Rs = 0.33; p = 0.006). Twenty days postoperatively, the LV volumetric parameters normalized; however, the EF did not reach the initial value. The longitudinal strain and strain rate were reduced preoperatively when compared with normal values. For the prediction of a postoperatively significant EF reduction (≤35%), the preoperative LV strain had a sensitivity of 88%, specificity of 98.2%, and cutoff value of –9.2%; the LV strain rate had a sensitivity of 87.8%, specificity of 94.7%, and cutoff value of –0.47 s−1.Conclusion. Children aged <1 year with perimembranous VSD showed reductions in the longitudinal mechanics of the LV, reflecting subclinical systolic dysfunction. One day after surgical correction, a transient decrease in LV systolic function was noted in all the children; however, a significantly impaired LV systolic function was noted in 10.8% of the children. Our findings indicate that the longitudinal mechanics of the LV can predict LV systolic dysfunction in the early postoperative period with high sensitivity and specificity.Received 17 January 2019. Revised 18 April 2019. Accepted 25 April 2019.Funding: The study did not have sponsorship.Conflict of interest: Authors declare no conflict of interest.
Building customer loyalty for light steel products “Kencana Truss” in Bali
Authors: Wijaya I Komang Adi Dana , Suprapti Ni Wayan Sri
Published: July 2019

The purpose of this study is to explain the effect of product quality on customer satisfaction mediated by brand image and brand trust, ultimately determining customer loyalty. The questionnaire distributed 175 copies to the users of Kencana Truss light steel in Bali Province, but valid for processing 133 copies. Data were analyzed using SEM (Structural Equation Modeling) analysis technique. The results of this study found that variable product quality, brand image, and brand trust have a significant positive effect on customer satisfaction. Customer satisfaction variables have a significant positive effect on customer loyalty. Variable brand image and brand trust, significantly mediate the effect of product quality on customer satisfaction. Similarly, customer satisfaction mediates the effect of brand image and brand trust on customer loyalty. The implications of the results of this study indicate that product quality is found as a major factor in increasing customer satisfaction which ultimately results in customer loyalty. Providers of light steel products should pay special attention to product quality, so customer satisfaction and loyalty can be maintained.
Design and Evaluation of a Contextual Model for Information Retrieval From Web-Scale Discovery Services to Improve Evidence-Based Practice by Health Care Practitioners: Mixed Methods Study
Authors: Miranda Alvet , Miah Shah Jahan
Published: July 2019

Background

Practicing evidence-based health care is challenging because of overwhelming results presented to practitioners by Google-like Web-scale discovery (WSD) services that index millions of resources while retrieving information based on relevancy algorithms with limited consideration for user information need.

Objective

On the basis of the user-oriented theory of information need and following design science principles, this study aimed to develop and evaluate an innovative contextual model for information retrieval from WSD services to improve evidence-based practice (EBP) by health care practitioners.

Methods

We identified problems from literature to support real-world requirements for this study. We used design science research methodology to guide artefact design. We iteratively improved prototype of the context model using artificial formative evaluation. We performed naturalistic summative evaluation using convergent interviewing of health care practitioners and content analysis from a confirmatory focus group consisting of health researchers to evaluate the model’s validity and utility.

Results

The study iteratively designed and applied the context model to a WSD service to meet 5 identified requirements. All 5 health care practitioners interviewed found the artefact satisfied the 5 requirements to successfully evaluate the model as having validity and utility. Content analysis results from the confirmatory focus group mapped top 5 descriptors per requirement to support a true hypothesis that there is significant discussion among participants to justify concluding that the artefact had validity and utility.

Conclusions

The context model for WSD satisfied all requirements and was evaluated successfully for information retrieval to improve EBP. Outcomes from this study justify further research into the model.
ANALYTICAL METHOD VALIDATION OF ICP-AES FOR ANALYSIS OF CADMIUM, CHROMIUM, CUPRUM, MANGAN AND NICKEL IN MILK
Authors: ALEXANDER DAVID , Rohman Abdul
Published: July 2019

Objective: The aim of this research was to validate inductively coupled plasma-atomic emission spectroscopy (ICP-AES) for quantitative analysis of cadmium (Cd), chromium (Cr), cuprum (Cu), mangan (Mn) and nickel (Ni) in milk products.

Methods: The heavy metals in milk were determined using ICP-AES at optimized wavelength. The method was validated by assessing several validation parameters which included linearity and range, accuracy, precision and sensitivity expressed by the limit of detection and limit of quantification. The validated method was then used for the analysis of milks commercially available.

Results: ICP-AES for determination of Cd, Cr, Cu, Mn, and Ni was linear over a certain concentration range with a coefficient correlation value of>0.997. The limit of quantification values of Cd, Cr, Cu, Mn, and Ni were 0.0047; 0.0050; 0.0066; 0.0061; and 0.0169 µg/ml, respectively. The precision of analytical method exhibited relative standard deviation (RSD) values of 3.18%; 4.17%; 3.05%; 2.93%; and 4.47% during repeatability test and 5.28%; 5.06%; 3.67%; 3.67%; and 11.17% during intermediate precision of Cd, Cr, Cu, Mn, and Ni respectively. The recoveries of these metals assessed using standard addition method were 92.25; 90.88; 102.87; 94.50; and 86.85%, respectively.

Conclusion: ICP-AES offered a reliable and fast method for the determination of heavy metals in milk products. The developed method could be proposed as an official method for determination of heavy metals in milk products.
FORMULATION, OPTIMIZATION, AND EVALUATION OF IN-SITU GEL OF MOXIFLOXACIN HYDROCHLORIDE FOR OPHTHALMIC DRUG DELIVERY
Authors: Gupta Chitra , JUYAL VIJAY , Nagaich Upendra
Published: July 2019

Objective: The present study emphasizes the synthesis, optimization, and evaluation of ocular in-situ gel for ophthalmic drug delivery against conjunctivitis.

Methods: Pre-formulation studies on the drug and polymers were carried out, which included the study of various physicochemical properties of the drug and drug-polymer compatibility studies. The 12 different formulations were further pre-optimised by Taguchi method for determining the number of influential factors. Furthermore, the formulation optimization was done by using ‘Box–Behnken’ design (BBD) (Design expert 10 software) for assessing the effect of formulation variables on product characteristics viz. viscosity, gelation temperature (GT), and mean release time (MRT). About 13 suggested runs of the experiment were carried out and formulations were optimised. Finally, three batches of the optimised formulation were prepared and evaluated for in vitro drug release, isotonicity of formulation, anti-microbial potential, ocular irritancy, and accelerated stability testing.

Results: Pre-formulation study confirmed the purity, solubility, and compatibility of drug measured by λmax, partition coefficient, stability study, and Fourier-transform infrared spectroscopy (FTIR) analysis. Taguchi screening method suggested about 12 different formulations and 3 most prominent influential factors including viscosity, GT, and drug release. 13 different formulations designed based on ‘BBD’ method were further optimised by considering the most influential factors suggested by Taguchi screening. The in vitro evaluation of the optimised formulation gave satisfactory results in terms of drug release, and anti-microbial activity. It was found to be isotonic with no ocular irritancy. Further, the preparation immediately transformed from sol to gel upon administration into cul-de-sac region of the eye due to multi-dimensional approaches utilised for in-situ gel formation namely temperature change Pluronic, ion sensitivity due to Gellan-gum, pH sensitivity because of Carbopol.

Conclusion: The optimised in-situ gelling ocular drug formulation showed promising potency for ophthalmic drug delivery with no irritancy due to the multifactorial mechanism.
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLET OF AMLODIPINE BESYLATE
Authors: BADWAR MEGHAWATI R. , BORSE SANDHYA L. , JUNAGADE MANISH S. , JADHAV ANIL G.
Published: July 2019

Objective: The main objective of this research work was to formulate and evaluate the mouth dissolving tablet of amlodipine besylate for the treatment of hypertension and coronary artery disease.

Methods: In this study, mouth dissolving tablet were prepared by direct compression method by using croscarmellose sodium and sodium starch glycolate as superdisintegrants. The designed tablets were subjected to various assessment parameters like friability test, hardness test, disintegration test, wetting time, in vitro drug release and drug content.

Results: All the prepared formulations were subjected to various assessment parameters, and the findings obtain within the prescribed limit. The calibration curve of pure drug using various solvents like phosphate buffer pH 6.8, methanol was plotted. F1-F9 containing croscarmellose sodium and sodium starch glycolate in various concentration demonstrate the minimum disintegration time. Among all these formulations F9 shows disintegration time up to 22±1.12 seconds due to the high concentration of superdisintegrants. In vitro drug release was tested in phosphate buffer pH 6.8 at a time interval of 0, 1, 2, 3, 4, 5 min. The F9 shows drug release 100.22±1.08%. Accelerated stability study of optimized formulation (F9) up to 2 mo showed there was no change in disintegration time and percentage drug release.

Conclusion: The results obtained in the research work clearly showed a promising potential of mouth dissolving tablets containing a specific ratio of croscarmellose sodium and sodium starch glycolate as superdisintegrants for the effective treatment of hypertension and coronary artery disease.
PREPARATION AND CHARACTERIZATION OF LIPOSOMAL DELIVERY SYSTEM OF NATURAL HEME PROTEIN
Authors: Katsai Oleksii , Ruban Olena
Published: July 2019

Objective: The objective of the present study was to develop and optimize the methods for preparation and characterization of the liposomal delivery system of natural heme protein.
Methods: Cytochrome C containing liposomes (Cyt-LS) were prepared by high-pressure homogenization technique using phosphatidylcholine (PC) and dipalmitoyl phosphatidylglycerol (DPPG). Nanoparticles were characterized by using: dynamic light scattering, zeta potential measurements, scanning electron microscopy and HPLC. The specific activity was studied in vitro.
Results: The study of homogenization regimes for obtaining unilamellar Cyt-LS was carried out. The selected temperature regime of homogenization was kept within 38–44 °С with optimal homogenization pressure of 800 bar. The obtained Cyt-LS were characterized by the main physicochemical parameters showed: Encapsulation efficiency 95.8±2.0%, Zeta potential-57±1.0 mV, pH-6.95±0.05. Phospholipid impurities had the following content: lysophosphatidylcholine-0.60±0.05% and free fatty acids-0.4±0.05%. The average particle diameter was 156±2 nm. Also, the size of Cyt-LS particles was confirmed by the ability of emulsion subjected to the sterilizing filtration with the preservation of its main physicochemical properties. Cyt-LS exhibit specific activity, similar to non-liposomal Cyt-C solution.
Conclusion: The formulation of the liposomal delivery system of heme protein was successfully prepared using natural components and evaluated for different parameters.
SELEKSI DAN UJI POTENSI CENDAWAN DARK SEPTATE ENDOPHYTE SEBAGAI AGENSIA HAYATI PENYAKIT JAMUR AKAR PUTIH (Rigidoporus microporus) PADA TANAMAN KARET
Authors: Dalimunthe Cici Indriani , Soekarno Bonny PW , Munif Abdul , Surono Surono
Published: July 2019

Cendawan Dark Septate Endophyte (DSE) adalah sekelompok cendawan endofit yang memiliki hifa melanin gelap, membentuk koloni berwarna gelap pada media agar dan mampu mengkolonisasi akar tanaman tanpa menyebabkan gejala penyakit. Belum ada laporan yang berkaitan dengan peran cendawan DSE sebagai agens pengendali penyakit akar putih, khususnya di Indonesia. Penelitian ini bertujuan untuk mendapatkan isolat DSE dari Indonesia dengan cara menseleksi isolat cendawan DSE yang berpotensi sebagai agensia hayati penyakit akar putih pada tanaman karet. Tahapan awal dari penelitian adalah isolasi cendawan DSE dari akar dan tanah di sekitar perakaran karet, uji patogensitas, uji dual culture dan uji metabolit senyawa volatil. Dalam penelitian ini, diperoleh lima isolat cendawan DSE APDS 3.2, TBMDS 2.4b, TMDS 2.1, TMDS 3.2 dan SBTBMDS 1 yang mampu menghambat pertumbuhan Rigidoporus microporus penyebab penyakit jamur akar putih pada tanaman karet. Penelitian ini membuktikan bahwa isolat cendawan DSE bisa diisolasi dari akar tanaman karet dan berpotensi sebagai agensia hayati Rigidoporus microporus penyebab penyakit jamur akar putih pada tanaman karet. Penelitian selanjutnya akan dilakukan pengujian lapangan dan diharapkan hasil dari penelitian ini akan memberikan informasi awal tentang peran cendawan DSE pada tanaman karet dalam mengatasi cekaman biotik yang disebabkan oleh cendawan pathogen.
POTENSI LASER (light amplification by stimulated emission of radiation) SEBAGAI PENDETEKSI BAKTERI (Studi awal detektor makanan halal)
Authors: Wan Hadi Kurnia
Published: July 2019

Penelitian untuk mengetahui keberadaan mikroorganisme pada sebuah benda merupakan kebutuhan yang sangat penting dilakukan. Bakteri Escericia coli sebagai mikroorganisme patogen banyak ditemukan didalam feses hewan. Penggunaan laser untuk mendeteksi keberadaan bakteri memberikan hasil yang cukup signifikan. Dengan panjang gelombang 532 nm dan 650 nm spektrum spekel bisa ditangkap oleh kamera CMOS 30 fps 12 mp dengan baik, sehingga dihasilkan intensitas kontras yang berbeda. Titik Sampel yang ada bakteri memeiliki nilai kontras yang lebih kecil dibandingkan denghan titik sampel yang tidak ada bakterinya.  Pengukuran intensitas dilakukan dengan menggunakan sofware Matlab 7 dengan arah penyinaran Vertikal dan sudut kamera 450
Pengaruh Variasi Lebar Sudu Mangkok terhadap Kinerja Turbin Kinetik Poros Vertikal
Authors: Ujiburrahman Ujiburrahman , Soenoko Rudy , Choiron Moch. Agus
Published: July 2019

Daya dan efisiensi merupakan parameter – parameter yang menjadi tolak ukur dari kinerja sebuah turbin kinetik. Penelitian sebelumnya menunjukan berbagai faktor seperti debit aliran, dimensi dan geometri dari turbin kinetik adalah varaibel – variabel yang mempengaruhi besarnya daya dan efisiensi. Dalam upaya meningkatkan kinerja turbin kinetik dibutuhkan pemahaman yang mendalam terhadap faktor – faktor yang mempengaruhinya. Oleh karena itu tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi lebar sudu mangkok terhadap kinerja turbin kinetik. Metode yang digunakan dalam penelitian ini adalah eksperimental nyata pada skala laboratorium. Pengujian dilakukan pada turbin kinetik poros vertikal dengan variasi lebar sudu 8 cm, 9 cm dan 10 cm. Setiap turbin diuji pada variasi debit air 45 m3/h, 50 m3/h, 55 m3/h, 60 m3/h dan 65 m3/h dan variasi putaran 20 rpm, 40 rpm, 60 rpm, 80 rpm dan 100 rpm. Hasil penelitian menunjukan bahwa lebar sudu mangkok mempengaruhi kinerja dari turbin kinetik dimana lebar sudu mangkok 10 cm memiliki kinerja lebih tinggi dari lebar sudu mangkok 8 cm dan 9 cm. Kinerja  tertinggi turbin kinetik pada variasi lebar sudu mangkok 10 cm diperoleh pada kondisi putaran 80 rpm dan debit 65 m3/h. Pada kondisi tersebut daya yang dihasilkan oleh turbin kinetik adalah 12,98 Watt dan efisiensinya 35,72 %.
PENGEMBANGAN WAKAF TANAH DAN RUMAH SUSUN BERDASARKAN ASAS PEMISAHAN HORIZONTAL
Authors: Kurniati Nia , Nova Lita Helza
Published: July 2019

Wakaf tanah dipergunakan untuk mendirikan bangunan bagi usaha dalam bidang keagamaan dan sosial. Sejak terbit UU Nomor 41 Tahun 2004, di dalam Pasal 16 ayat (2) huruf d, dinyatakan, harta benda wakaf berupa tanah dan rumah susun difungsikan selain sebagai sarana keagamaan, juga untuk memajukan kesejahteraan umum. Melalui metode yuridis normatif, artikel ini mencoba memberikan landasan pemikiran, mengenai pembaharuan hukum wakaf produktif, dengan menerapkan asas pemisahan horizontal untuk mengembangkan potensi ekonomi harta benda wakaf berupa tanah dan rumah susun melalui kerjasama dengan pihak ketiga, menghasilkan keuntungan tanpa melanggar prinsip syariah dan kewenangan Nazhir sebagai pemegang hak tanah wakaf.
Demand Drivers of Female Labor Force Participation: Evidence From Selected African Countries
Authors: Idowu Omowumi O.
Published: July 2019

This study investigates the demand drivers of female labor participation in a panel of twenty (20) selected African countries across five sub-regional groupings (West Africa, East Africa, North Africa, Central Africa and South Africa), over the period 1990-2015. The study sourced data from World Bank Data Bank. Poverty and gender inequality in employment were used and measured respectively by life expectancy at birth and gender ratio in labor participation. Other variables included are wage rates, female marginal labor productivity and household income. Autoregressive Distributive Lags (ARDL) procedure of dynamic panel model was used. The result from the Dynamic Fixed Effect (DFE) revealed that female marginal productivity of labor and gender inequality in employment have a significant positive impact on demand for female labor in the long run, however female marginal productivity was found negative in the short run. It is therefore important that, in order to bridge the gender gap in employment, government should ensure gender sensitive policies and remove all forms of institutional barriers to female labor demand. Efforts should also be made to improve female productivity through training, literacy and household food security. In order for female demand to meet desired response, adequate support services and provisions that can entice female to work outside home should be provided.
Personalized Marketing in the Function of the Tourist Destination Improvement
Authors: Mitrović Dijana Medenica , Simović Olivera , Raičević Milica
Published: July 2019

Trends in marketing are changing and adopting new technologies, but what always remains is good content and relevant data. New knowledge, information and use of new tools are often crucial for the success of a company. Modern business in the domain of personal marketing can no longer be efficiently implemented without the use of new e-technologies. The application of Internet technology implies radical changes in marketing (strategies, plans, programs, communication) that have contributed to the development of personal marketing, and thus improved “face to face” communication between bidders and consumers. The theoretical part of the paper refers to defining the role and importance of personalized marketing in the function of improving the business, especially from the aspect of approaching each customer or customer segment individually, as well as the importance of applying social networks to marketing, as well as the specificities and benefits of this type of marketing. The practical part in the focus has the research of the importance and role of social networks in the implementation of personalized marketing, as well as in the process of selecting a tourist destination. The practical part of the paper includes research through a specially designed questionnaire, conducted on the territory of Montenegro, and provides information on how important social networks are for selecting the tourist destination and the offer that a particular destination. The aim of the paper is to draw attention to the importance of a good e-market strategy, also, to the approach that gives the best results in advertising and the achievement of the results of the tourist destination and its offer, sales, communication with consumers, establishment of long-term relationships with consumers, which also affects improvement of the business of every tourist company in general.
Transforming Accounting Education Through Educators’ Consciousness: A Theatrical Perspective
Authors: Kamayanti Ari
Published: July 2019

AbstractObjective – Study aims to portrait how changes in accounting education should start with ac-counting educators’ consciousness and how to trigger this consciousness. Design/methodology – This study offers alternative perspective to enhance accounting education through educators’ consciousness. This study took place in ACURA that was established in May 1986 in Surabaya by a group of public state university lecturers. By employing a qualitative approach namely dramaturgical interventionism study in a private university, the changes of accounting lecturers consciousness were observed and presented. Results – It is found that educators’ consciousness is necessary to change the course of accounting education to be geared for civilization. The most important trait that an accounting education has is a continuously critically conscious (3C) character.  However, the critical consciousness is only part that will make up ‘self’ consciousness. Research limitations/implications – This findings could be transferrable to other institutions with similar context.  This also opens up another door to further research, especially one that is applicative in nature.
First Molecular Identification of Sunfish in North Bali Water
Authors: Riawan I Made Oka , Setiabudi Gede Iwan , Merdana I Made , Mariasa I Putu Mangku , Wirasastra Kadek Teguh
Published: July 2019

Stranded Sunfish in North Bali with full body we collect to do molecular identification. Samples were amplified at the d-loop locus (control region) using the PCR (Polymerase Chain Reaction) method. Primers used in PCR are H16498 as primary front (forward) and L15812 as reverse primer. Similarity value of 95% after alignment with Mola ramsayi (accession number accession AY940824) on GenBank, and the gaps of the nucleotide just 1%. The stranded sunfish identified using partial sequence mtDNA is the same species as the species Mola ramsayi.
Estatutos jurídicos e processos de nacionalização de línguas no Brasil
Authors: ABREU Ricardo Nascimento
Published: July 2019

A Constituição Brasileira de 1988 inaugura uma nova cena nas políticas linguísticas da história constitucional do país, ao registrar, pela primeira vez, a existência de uma língua oficial para servir de instrumento de suporte da organização estatal e reforçar a sua condição de nação soberana perante a comunidade internacional. A decisão política de elevar a língua portuguesa à condição de idioma oficial não foi seguida de um processo de planejamento legislativo e do desenvolvimento de uma teoria política dos direitos linguísticos com a finalidade de definir os lugares jurídicos das demais línguas constitutivas da realidade multilíngue nacional. Assim, além de termos no país a existência de línguas sem estatuto jurídico algum, ou seja, línguas sem nenhuma proteção jurídica por parte do Estado, encontramos também, no conjunto daqueles idiomas que lograram êxito em conseguir o amparo estatal, um cenário bastante confuso e, por vezes, inibidor do desenvolvimento de políticas mais robustas de nacionalização das nossas línguas. Objetivamos elucidar as circunstâncias que levaram a esse panorama de extrema fragilidade nas diretrizes de classificação dos estatutos jurídicos dos idiomas e, em seguida, apresentaremos alguns dos principais processos de nacionalização de línguas adotados pelo Brasil após a promulgação da “Constituição Cidadã”.
Nizip yağlık, Saurani ve Uslu Zeytin Çeşitlerinin Döllenme Biyolojilerinin Araştırılması
Authors: METE Nurengin , ÇETİN Öznur , HAKAN Mehmet , KAYA Hülya , SEFER Filiz , ULUÇAY Nurcan , GÜLOĞLU Uğur , GÜL Hükümran , SEZGİN Oktay
Published: July 2019

Bu çalışma ile Türkiye zeytin ağaç varlığında önemli
bir yer tutan Saurani, Nizip yağlık ve Uslu çeşitlerinin döllenme biyolojileri
araştırılmıştır. Bu amaçla 3 yıl süre
ile serbest tozlanma, karşılıklı tozlama ve kendileme uygulamaları
yapılarak çeşitlerin kendine verimlilik durumu ve uygun tozlayıcıları incelenmiştir.
Çalışma neticesinde çeşitlerin kendine verimliliği ve tozlayıcıların etkinlik
derecelerinin yıllar arasında değişebileceği görülmüştür. Bununla birlikte,
yabancı tozlanmanın kendileme uygulamasına göre birçok durumda meyve tutumunu
arttırdığı saptanmıştır. Bu nedenle kendine verimli olduğu düşünülen çeşitlerde
dahi yabancı tozlanmanın gerekliliği ortaya konmuştur. Çalışmada, Nizip yağlık
çeşidi kısmen kendine verimli olarak değerlendirilmiştir. Memecik ve Kilis
yağlık çeşitlerinin Nizip yağlık çeşidi için uygun tozlayıcılar olabileceği
düşünülmektedir. Saurani zeytin çeşidi verimlilik indeks değerlerine göre
kendine verimli olarak bulunmuştur. Ancak meyve tutumunu arttırmak için Halhalı
çelebi, Gemlik, Memecik ve Nizip yağlık çeşitlerinin uygun tozlayıcılar olarak
kullanılabileceği düşünülmektedir. Uslu çeşidi de verimlilik indeks değerlerine
göre kendine verimli olarak saptanmıştır. Bununla birlikte Gemlik, Memecik ve
Erkence çeşitlerinin meyve tutumunu arttırmada etkili olduğu görülmüştür.
Acute heart failure and microRNA
Authors: Nasonova Svetlana N , Mindzaev Dzambolat R , Zhirov Igor V , Tereshchenko Sergei N
Published: July 2019

MicroRNA is a class of non-coding, single-stranded RNA 19-24 nucleotides in length, the main function of which is to inhibit the expression of protein-coding genes at the post-transcriptional level. It is known that microRNAs are an important pathogenetic link in the development of many diseases, including cardiovascular ones. Different levels of expression of these molecules in different pathologies make microRNAs potential diagnostic and prognostic biomarkers. Numerous studies confirm the fact of changes in the profile of microRNA expression in heart failure (HF). However, it is worth noting that the vast majority of these studies included patients with stable chronic HF, while the connection of these molecules with acute HF has received far less attention. Acute HF is the main cause of hospitalization for older patients. However, taking into account the low prognostic ability of existing biological markers of HF, the search for a new biological marker with a high prognostic significance is an important task of modern medicine. The article provides a brief overview of the research on the evaluation of diagnostic and prognostic abilities of a new potential of the biomarker in acute HF.
Seleksi Penerima Beasiswa Dengan Metode Fuzzy Multi-Attribute Decision Making Dengan Pengembangan
Authors: Monemnasi Markus , Rozi Anief Fauzan
Published: July 2019

Beasiswa merupakan pemberian berupa bantuan keuangan yang diberikan kepada perorangan bertujuan untuk digunakan demi keberlangsungan pendidikan. Bantuan ini dapat diberikan oleh lembaga pemerintahan, perusahaan atau yayasan. Sekolah Menengah Atas Tiga Maret (SMA GAMA) Yogyakarta memiliki program pemberian beasiswa kepada siswa miskin atau kurang mampu di sekolah tersebut. Akan tetapi dalam melakukan seleksi beasiswa tersebut mengalami banyak kesulitan karena proses seleksinya masih manual serta banyaknya siswa yang mengajukan dan banyaknya kriteria yang digunakan sehingga dalam proses penentuannya menyita waktu yang banyak.Oleh karena itu diperlukan sebuah sistem yang membantu, mempercepat dan mempermudah pihak yang bersangkutan dalam proses seleksinya. Proses pengambil keputusan dibangun menggunakan metode fuzzy multi-attribute decision making. Metode ini akan membantu pengambil keputusan pada situasi dimana terdapat banyak alternatif keputusan dengan beberapa kriteria. Dipilihnya fuzzy multi-attribute decision making karena karakternya sangat tepat untuk menyelesaikan permasalahan yang semi-terstruktur seperti masalah beasiswa ini, juga merupakan metode yang akan cukup akurat memberikan hasil yang diharapkan serta akan mampu juga mengurangi kesalahan-kesalahan proses seleksi dan mempercepat proses pengambilan keputusannya.Hasil akhir dari sistem yang dibuat berupa rekomendasi penerima beasiswa dengan nilai total tertinggi dimana sebelumnya sistem akan melakukan perhitungan dan seleksi dari data yang telah dimasukan yang selanjutnya akan diurutkan dari nilai total integral tertinggi hingga nilai total integral terendah sehingga pengguna dapat dengan mudah menentukan siapa yang berhak dan layak untuk menerima beasiswa dan yang paling sesuai dengan kriteria yang telah ditetapkan.
Estatuto de Museus, Comunicação e Museus de Tribunais Superiores do Judiciário no Brasil
Authors: Silva Robson De Goes e , Paulino Fernando Oliveira
Published: July 2019

Este artigo buscou verificar se museus localizados em tribunais superiores (STF, STJ, STM, TSE e TST) têm levado em conta ou não as diretrizes previstas pelo Estatuto de Museus, Lei 11.904/2009, principalmente no que se refere às atividades ligadas à comunicação. Para isso, a pesquisa utilizou a metodologia da Hermenêutica de Profundidade, desenvolvida inicialmente por Thompson (1995). Utilizando alguns artigos da lei como parâmetro de análise, foi possível, concluir que embora em vigor há nove anos, o Estatuto não tem sido efetivamente cumprido pelas próprias instituições ligadas ao Poder Judiciário.
Trois archives : films scientifiques et histoires de décontextualisation
Authors: Bernabei Maria Ida
Published: July 2019

Existe uma intima e antiga ligação entre o cinema científico e o cinema de vanguarda. Na década de 1920, de fato, o primeiro contribuiu para a construção do segundo. Por um lado, pela sua inclusão sistemática na programação das salas especializadas e em cineclubes, e por outro lado catalisando a reflexão teórica sobre a especificidade do meio, em razão das técnicas específicas desenvolvidas, em particular a câmera-lenta, a câmera rápida, a micro-cinematografia, a radiocinematografia e as filmagens submarinas. Neste artigo nós vamos estudar esse processo de deslocamento, re-semantização, ou mesmo re-location do filme científico, abrindo as portas de três grandes arquivos europeus e nos concentrando em seis filmes que eles preservam.
Precisamos de um museu do cinema
Authors: Rezende Paula Davies
Published: July 2019

Neste artigo faço uma análise dos equipamentos de cinema e fotografia por diferentes óticas: como artefato portador de significado e reflexo da dinâmica da sociedade que o criou, como mediador e modificador da relação humana com a imagem técnica e como agente atuante na criação estética. Por fim, trato da necessidade de musealização desses objetos tecnológicos, trazendo como exemplo o acervo de tecnologia cinematográfica da Cinemateca do Museu de Arte Moderna do Rio de Janeiro.
Physical characteristics of nanoemulsion from chitosan/nutmeg seed oil and
evaluation of its coating against microbial growth on strawberry
Authors: Horison R. , Sulaiman F.O. , Alfredo D. , Wardana A.A.
Published: July 2019

The objectives of this research were to characterize nanoemulsion from chitosan/nutmeg
seed oil and to evaluate its coating on fresh strawberry which stored at 10oC for 5 days.
The ultraturrax and high-pressure homogenizer were used to prepare 1.34±0.25 -
5.79±1.61 nm of nanoemulsion size which confirmed by particle size analyzer. The
morphology observed by SEM that exhibited the oil globules were covered by chitosan.
They were aggregated and rough droplets. Interactions among the materials were observed
using FTIR which led to the presence of a new peak at 1736 cm-1
. The coated strawberry
by high-pressure homogenizer-emulsion showed the best result suppressing microbial
(2.41±0.01) and mould-yeast (2.78±0.10) growth at the end of storage compared to control
which were 3.37±0.02 and 3.69±0.14 for microbial and mould-yeast count respectively.
Els goigs valencians de Sant Vicent Ferrer: cant, lloança i lloança al sant
Authors: Gomis Corell Joan Carles
Published: July 2019

D’entre les pregàries i oracions que assíduament practicava el beat fra Gaspar Bono, José Vicente Ortí y Mayor [1750: 73] ja distingia aquelles que consistien en «[…] cantar algunas alabanzas a los santos (que ordinariamente llamamos gozos) […]». Efectivament, els goigs, en els termes que els entenen a hores d’ara tant que gènere poètico-musical, són himnes religiosos, cant de lloança als personatges i misteris celestials. Per això el títol d’aquesta intervenció trasllada als goigs de sant Vicent Ferrer la famosa definició, considerada fins i tot canònica, que sant Agostí (Enarr. CXLVIII, 17) donà d’himne cristià: «[…] cant, lloança i lloança a Déu. Aleshores, la lloança de Déu en el cant s’anomena hinme».
DEVELOPMENT DESIGN OF SELECTIVE LISTENING LEARNING MATERIAL BASED ON CORRELATED CORE WITH THE APPLICATION OF LISTENING IN ACTION METHODS
Authors: Pulungan Dedi Zulkarnain , Nasution Fauziah , Adawiyah Robiyatul , Tambunan Elissa Evawani , Sibuea Erni Rawati
Published: July 2019

The design of the development of learning methods involves the pattern of organizing elements or components in the curriculum. the development of learning materials listening to correlated core-based learning with the application of listening in action methods seen from two dimensions, namely horizontal and vertical dimensions. The horizontal dimension is related to the compilation of the scope of learning content. This spatial arrangement is often integrated with the learning and teaching process. The vertical dimension concerns the compilation of material sequences based on the order of difficulty. Arranged materials start from the easy ones, then go to the more difficult ones, or start with the basic ones followed by the continuation. This development describes in detail about the components that must be present in each listening learning material that can be used for the learning process. The design of the development of the listening learning material consists of several components, including the objectives of the curriculum, teaching materials or the material or content of the curriculum, teaching strategies or teaching methods, teaching media and teaching evaluation and improving teaching. These components are related to each other in the development of learning materials listening to correlated core-based learning by applying listening in action methods.
The Youth Labour Market, Populism and the
Digitalization of Economies
Authors: González Fabre Raúl
Published: July 2019

Firstly, a basic understanding of economic competition and its role in the lives of the youth is presented. Then two forces are described which have affected the lowest echelons of the labour competition market during the last decade and the political reactions (xenophobic, anti–system) which ensued. Finally, some ideas are summarized which were presented at the discussion on the competitive impact of artificial intelligence (AI) on the labour market, some of the responses proposed and the basic difficulties that affect them. We conclude that one must expect further political convulsions following infringements of the AI upon the structure of the youth labour market.
CALCULATION OF STRETCHING AND BENDING STRESS IN A CASING STRING INSTALLED IN A WELL WITH A COMPLEX PROFILE
Authors: Paliychuk I. I.
Published: July 2019

The casing column in the curvilinear well is represented as a long solid elastic rod. It has a vertically actingweight, which is evenly distributed along the length and creates variable axial tensile forces in the column body. At the same time, it is influenced by the reaction forces of the borehole walls, which, together with the weight, bend the column of initially straight pipes. It is assumed that the casing axis replicates the axis of the bent borehole, and the walls reaction is continuously distributed along the length according to a certain law, which, together with the weight, bends the column of the initially straight pipes. A system of differential equilibrium equations of internal and external forces and moments was composed. This system was supplemented to a closed form with the differential equation of curvature. This system describes large deformations of a long elastic rod in one plane. The introduction of the distributed weight, wall reactions and resistance forces into the calculation makes it non-uniform. Its feature is the need to solve the inverse problem. In this case the external load and rod deformations defined by the well shape in the form of an inclinometric data table are known. The unknown internal forces and the function of the walls reaction which creates its predetermined shape must be determined. It is established that this function depends on the distribution of axial forces caused by weight and resistance forces. As a result the system was reduced to a linear inhomogeneous differential equation with variable coefficients of the first order as to the axialforce and its solution was obtained as a sum of integrals. It is shown that one of them can be found in quadratures only in the case of a constant radius of curvature of the well. This necessitated the use of numerical integration methods. Formulas for the distribution of axial forces and bending moments in the body of the column, as well as the reactions of the walls leading the column to the actual well profile are obtained from the solution of the basic equation. To calculate these force factors, a method for numerical integration of inclinometric measurements data and software for numerical analysis of a real well are developed. This technique allows to detect the areas of local increase of the curvature and difficult passage of the curvilinear wellbore and to calculate the main parameters of the stress-strain state of the casing column in it.
Systematic Reviews and Meta-analysis: Principles and Practice
Authors: Shrestha Badri Man
Published: July 2019

N/A
Computable Contact Algebras
Authors: Bazhenov Nikolay
Published: July 2019

We investigate computability-theoretic properties of contact algebras. These structures were introduced by Dimov and Vakarelov in [Fundam. Inform. 74 (2006), 209–249] as an axiomatization for the region-based theory of space. We prove that the class of countable contact algebras is complete with respect to degree spectra of nontrivial structures, effective dimensions, expansion by constants, and degree spectra of relations. This means that the class of contact algebras is very rich from the computability-theoretic point of view. As an application of our result, we show that the ∏3-theory of contact algebras is hereditarily undecidable. This is a refinement of the result of Koppelberg, Düntsch, and Winter [Algebra Univers., 68 (2012), 353–366].
Approximate Hotspots of Orthogonal Trajectories
Authors: Rudi Ali Gholami
Published: July 2019

We study the problem of finding hotspots, i.e. regions, in which a moving entity spends a significant amount of time, for polygonal trajectories. The fastest exact algorithm, due to Gudmundsson, van Kreveld, and Staals (2013) finds an axis-parallel square hotspot of fixed side length in O( n2) for a trajectory with n edges. Limiting ourselves to the case in which the entity moves in a direction parallel either to the x or to the y-axis, we present an approximation algorithm with the time complexity O( n log3 n) and approximation factor 1/2.
Carotid Atherosclerosis and Cognitive Function in a General Population Aged 63-65 Years: Data from the Akershus Cardiac Examination (ACE) 1950 Study
Authors: Ihle-Hansen Håkon , Vigen Thea , Berge Trygve , Hagberg Guri , Engedal Knut , Rønning Ole Morten , Thommessen Bente , Lyngbakken Magnus N. , Nygård Ståle , Røsjø Helge , Tveit Arnljot , Ihle-Hansen Hege
Published: July 2019

Background:

Studies on the relationship between carotid atherosclerosis and cognitive function in subjects from the general population are few and results have been inconsistent.

Objective:

We aimed to investigate the association between carotid atherosclerotic burden and cognitive function in a cross-sectional analysis of a population-based cohort aged 63–65 years.

Methods:

All habitants born in 1950 from Akershus County, Norway were invited to participate. A linear regression model was used to assess the association between carotid atherosclerosis and cognitive function. We used carotid plaque score as a measure of carotid atherosclerotic burden and the Montreal Cognitive Assessment (MoCA) for global cognitive function.

Results:

We analyzed 3,413 individuals aged 63–65 with mean MoCA score 25.3±2.9 and 87% visible carotid plaques. We found a negative correlation between carotid plaque score and MoCA score (r = –0.14, p < 0.001), but this association was lost in multivariable analysis. In contrast, diameter or area of the thickest plaque was independently associated with MoCA score. Lower educational level, male sex, current smoking, and diabetes were also associated with lower MoCA score in multivariable analysis.

Conclusion:

Carotid atherosclerotic burden was, unlike other measures of advanced carotid atherosclerosis, not independently associated with global cognitive function.
Cyclic AMP-Dependent Protein Kinase Phosphorylates TDP-43 and Modulates Its Function in Tau mRNA Processing
Authors: Gu Jianlan , Chu Dandan , Jin Nana , Chen Feng , Liu Fei
Published: July 2019

Trans-active response DNA-binding protein of 43 kDa (TDP-43) is a highly conserved and ubiquitously expressed nuclear protein. As a member of heterogeneous ribonucleoproteins, TDP-43 plays pivotal roles in mRNA processing. We recently found that TDP-43 promoted tau mRNA instability via acting on the 3’-untranslated region of its mRNA and enhanced tau exon 10 inclusion. TDP-43 is a phospho-protein. The function and the pathological aggregation of TDP-43 are regulated by the phosphorylation. In the present study, we determined phosphorylation of TDP-43 by cyclic AMP-dependent protein kinase (PKA). We found that TDP-43 was co-immunoprecipitated by and co-localized with PKA in the nucleus. PKA phosphorylated TDP-43 at Ser379, Ser403/404, and Ser409/410 in vitro and in cultured cells. Phosphorylation of TDP-43 at these sites enhanced mutually their phosphorylation by PKA in vitro and in cultured cells. Overexpression of PKA suppressed TDP-43’s activity in promoting tau mRNA instability and tau exon 10 inclusion. These findings shed light on the role of PKA in phosphorylation and function of TDP-43. Downregulation of PKA signaling in AD brain may attenuate the impact of TDP-43 pathology in tau pathogenesis.
三维CAD技术在机械制图教学中的有效应用
Authors: 王 莉
Published: July 2019

三维CAD在机械制图教学中的应用颠覆了传统机械制图教学模式,其可迅速培养学生的空间想象力,提高自主学习能力。三维CAD技术应用在机械制图中,是社会发展、当前科技和知识经济时代人才培养的必然趋势。
Realization of the "Transport task" simulation software using the "Drag-and-drop" technology
Authors: Malkina Vira , Zinovieva Olha , Mozghovenko Andrii
Published: July 2019

The modern educational process is becoming increasingly innovative. The most important means of educational activity are computer technology learning. The development and introduction of them into the educational process is a qualitative characteristic of the computerization of education and lay the foundations for its further informatization. The article deals with the structure and content of the initial computer simulation software or the study of the "Transport task" topic, which is intended for the development of knowledge, skills and abilities of students of computer specialties in the process of studying the "Investigation of operations" discipline. The training simulation software provides multiple passage of the material at each separate stage until the correct solution is obtained. To organize the interactive learning process, the "Drag-and-drop" method is used, which, on the one hand, allows us to use more observatory visual diagrams of the problem solving algorithm, and on the other hand, concentrates the attention of students on the main stages of the algorithm and not on the implementation of bulky mathematical calculations. The simulator is designed as a local Windows application that does not require special computer resources and can be easily installed on a personal computer in an auditorium or at home. The simulator can function in two modes – practice and supervision. The simulator can be used during classes and in the process of independent work.
The training simulator differs from other types of training devices by the obligatory availability of a script for verifying the actions that the student must perform in order to accomplish the task. In the process of executing actions and commands in the simulator, the verification of expected actions in the script is performed, after the result is displayed to the user. After that, in case of wrong actions, the user is given the opportunity to correct the errors. Only after correcting them, the user can go to the next stage of solving the problem. The user receives feedback and can find out about their mistakes and ability to correct them.
Dilbilimsel Açıdan Yabancı Dil Olarak Türkçe Öğrenen Bireylerin Yaptıkları Çeviri Hataları
Authors: BAYAZIT Zeynep Zeliha
Published: July 2019

Alan yazında özellikle de yabancı dil olarak Türkçeyi
öğrenen ve anadili İngilizce olan bireylerin iki dil arasında daha çok
karşılaştırma yaptıkları, dahası çoğu zaman da kendi anadillerinde düşünerek
dilsel hatalar yaptıkları belirtilmektedir. Bu anlamda yabancı dil olarak
Türkçe öğretiminde sorun odaklı yaklaşımlara yönelik araştırmalar oldukça önem
kazanmaktadır. Sorun odaklı yaklaşımlardan biri olan hata analizi yöntemi,
ikinci dil öğrenme sürecinin incelenmesi açısından oldukça önemli ipuçları
vermektedir. Bu nedenle bu çalışmada, anadili İngilizce olan ve Türkçeyi
yabancı dil olarak öğrenen bireyler ile ikinci yabancı dil olarak Türkçe
öğrenen öğrencilerin en çok yaptıkları dilbilimsel hataları, hata analizi
bulgularından yararlanarak belirlemek amaçlanmıştır. Çalışma, Ortadoğu Teknik
Üniversitesi (ODTÜ) Türk Dili Bölümü ve İndiana Üniversitesi Turkish Flagship
Programında yabancı dil olarak Türkçe öğrenen B1-B2 seviyesindeki 80 (40 ODTÜ +
40 Turkish Flagship) birey üzerinde yürütülmüştür. Öğrenci hatalarını saptamak
için öğrencilere “New to Turkey” başlıklı İngilizce metin verilmiş ve
öğrencilerden bu metni Türkçeye çevirmeleri istenmiştir. İçerik analizi
tekniğinin kullanıldığı çalışmanın sonunda öğrencilerin daha çok sözdizimsel ve
dilbilgisel yanlışlardan kaynaklı dilbilimsel hatalar yaptığı görülmüştür.