bluuebunny/crossref_metadata_2025 huggingface dataset:
Key concepts for intra-articular corticosteroid injections for pathology of the first metatarsophalangeal joint: a scoping review protocol
Authors: Reilly Ian Neil
Published: September 2021

ABSTRACTBackground: The two most common diseases affecting the first metatarso-phalangeal joint (1st MTP jt) of the foot are hallux limitus/rigidus (osteoarthritis) and hallux valgus (bunion), but other pathologies also affect the region. There are a range of treatments for these conditions: one treatment option is intra articular injection therapy, and this is one of the most common therapeutic interventions in musculoskeletal healthcare. Therapeutic injections of corticosteroids provide a treatment option for patients with joint or peri-articular pain, those who are not surgical candidates, in those in whom conservative treatment has failed or for those awaiting surgery. They are accepted as an important treatment modality, but currently there are no evidenced-based guidelines about administration technique or regimen of the 1st MTP jt. This is a scoping review protocol for the study to identify key concepts in intra-articular corticosteroid injections for pathology of the first metatarsophalangeal joint.Methods and analysis: Scoping reviews are used to assess and understand the extent of the knowledge in an emerging field or to identify, map, report, or discuss the characteristics or concepts in that field. The Joanna Briggs Institute (JBI) is an international research organisation based in the Faculty of Health and Medical Sciences at the University of Adelaide. The JBI develops and delivers evidence-based information, software, education, and training and its guidance is widely cited across a range of disciplines, academic fields, and professional backgrounds. This scoping review will follow the JBI process who recommend the PCC framework (‘Population–Concept–Context’) to frame the research question. The ‘Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for Scoping Reviews’ will be used to guide the reporting of this protocol and will also subsequently be used to structure the reporting of the full review (PRISMA-ScR). Dissemination: Findings will be presented to explore speciality-specific and profession-specific commonalities and differences. The scoping review results will be disseminated via publication in peer-reviewed journals (it is envisaged that at least two publications will be developed) and presentation at national/international conferences.
Interpretable Models Capture the Complex Relationship Between Climate Indices and Fire Season Intensity in Maritime Southeast Asia
Authors: Daniels William , Hammerling Dorit , Buchholz Rebecca , Worden Helen , Ahamad Fatimah
Published: September 2021

There have been many extreme fire seasons in Maritime Southeast Asia (MSEA) over the last two decades, a trend which will likely continue or accelerate due to climate change. Fires, in turn, are a major driver of atmospheric carbon monoxide (CO) variability, especially in the Southern Hemisphere. Here we attempt to maximize the amount of CO variability that can be explained via human-interpretable statistical models that use only climate mode indices as predictor variables. We expand upon previous work through the complexity at which we study the connections between climate mode indices and atmospheric CO (a proxy for fire intensity). Specifically, we present three modeling advancements. First, we analyze five different climate modes at a weekly timescale, which increases explained variability by 15% over models on a monthly timescale. Second, we accommodate multiple lead times for each climate mode index, finding that some indices have very different effects on CO at different lead times. Finally, we model the interactions between climate mode indices at weekly timescales, which provides a framework for studying these interactions at a higher level of complexity than previous work. Furthermore, we perform a stability analysis and show that our model for the MSEA region is robust, which adds weight to the scientific interpretation of the selected model terms. We believe that the complex relationships quantified here will be useful for scientists studying modes of variability in MSEA and for forecasters looking to maximize the information they glean from climate modes.
The Great Gatsby Curve
Authors: Durlauf Steven N. , Kourtellos Andros , Tan Chih Ming
Published: September 2021

This paper provides a synthesis of theoretical and empirical work on the Great Gatsby Curve, the positive empirical relationship between cross-section income inequality and persistence of income across generations. We present statistical models of income dynamics that mechanically give rise to the relationship between inequality and mobility. Five distinct classes of theories, including models on family investments, skills, social influences, political economy, and aspirations are developed, each providing a behavioral mechanism to explain the relationship. Finally, we review empirical studies that provide evidence of the curve for a range of contexts and socioeconomic outcomes as well as explore evidence on mechanisms. (Stone Center on Socio-Economic Inequality Working Paper)
Deterministic and Stochastic Holling-Tanner Prey-Predator Models
Authors: Thapa Bharat Bahadur , Shrestha Samir , Gurung Dil Bahadur
Published: September 2021

A modified version of the so called Holling-Tanner prey-predator models with prey dependent functional response is introduced. We improved some new results on Holling-Tanner model from Lotka-Volterra model on real ecological systems and studied the stability of this model in the deterministic and stochastic environments. The study was focused on three types of stability, namely, stable node, spiral node, and center. The numerical schemes are employed to get the approximated solutions of the differential equations. We have used Euler scheme to solve the deterministic prey-predator model and we used Euler-Maruyama scheme to solve stochastic prey-predator model.
Techno-Economic Analysis of the placement of the Capacitor in the Integrated Nepal Power System
Authors: Thakuri Manisha Shahi , Darlami Hari Bahadur
Published: September 2021

With the increasing load demand, Integrated Nepal Power System (INPS) is facing a stiff challenge to maintain voltage profile within the standards and reduce system loss. Among the loss reduction strategies, an immediate solution would be installation of reactive power compensators at the grid substations. The power flow study of existing system is performed and a genetic algorithm is used to find optimum placement of suitable size of the capacitor banks to be added in system. 6 substations with a total reactive power supply of 80 MVAR was determined as optimal size and location and the installation is also financially feasible. Moreover, the analysis of capacitors placed at the varying voltage levels implied that the most suitable voltage level for the capacitor installation is 11kV.
Utilization of Personal Protective Equipment in Construction Industry of Nepal
Authors: Acharya Uddhav Raj , Shrestha Santosh Kumar
Published: September 2021

Construction industry is one of the most dangerous industries worldwide. Use of personal protective equipment reduces injuries associated with it. This study has been undertaken to find out safety improvement measures and enforcement of statutory provisions available for safety practices, to analyze the current issues regarding application of PPE and to identify key factors preventing effective use of safety wears in construction industry of Nepal. The methodology adopted consists of comprehensive review of literature and questionnaire survey.100 sets of questionnaires to the professionals and 385 to the site operatives were administered. The collected data were analyzed using relative mean score and independent samples test and then ranked as per their significance. This study concluded that routine check of scaffold and ladder, in house safety training, daily consciousness of safety practice, etc. will improve workers’ safety practices. Wearing PPE can help protect from work related injuries, feeling responsible for wearing PPE all the times, asking supervisors for provision of appropriate and adequate PPE but the management has not maintained sufficient stock of appropriate safety wears are the current issues regarding application of PPE. Based on the result of Independent Samples T-test, safety wears are not comfortable to wear with, operatives’ engagement in improper conduct that could endanger their safety, ineffective communication between safety managers and workers are the major factors preventing effective use of safety wears.
The effect of crop rotation on the soil biological activity
Authors: Zamyatin S. А. , Maksimova R. В.
Published: September 2021

The current paper has presented the results of long-term experiments on the study of the biological activity of sod-podzolic soil by the application method in field crop rotations. The experimental part of the work was carried out on the experimental plots of the Mari Research Institute of Agriculture, a branch of the FSBSI FARC of the North-East in 1996–2020. The trials were laid down in 1996 and 1998. The trial was laid down in two factors. Factor A included such types of crop rotations as grain-grasses crop rotations (oats + clover, clover of 1 year of use, winter crops, vetch-oat mixture for grain, spring wheat, barley as a control grain crop); the first rotation of crops (annual leguminous grasses, winter crops, barley, potatoes, vetch-oat mixture for grain, spring wheat); the second rotation of crops (vetch-oat mix[1]ture for grain, spring wheat, potatoes fertilized with manure (80 t/ha), barley + clover, clover of 1 year of use, winter crops); the third rotation of crops (barley + clover, clover of 1 year of use, clover of 2 years of use, winter crops, pota[1]toes, oats). Factor B included application of mineral fertilizers: control grain crop (without fertilizers); N60P60K60. There has been established that the activity of soil microflora mainly depended on the presence of organic matter in the soil. The largest activity of cellulose-destroying microorganisms against a natural background of fertility was identified in the second rotation of crops, with the introduction 23.9% of manure for potatoes in the first period (45 days) and 54.7% in the second period (90 days) of exposure. The slightest biological activity of the soil was identified in the grain-grasses crop rotation (with 83% of grain crops); it was 17.7% in the first 45 days and 43.4% in the second period of exposure. That was caused by the deficit of organic matter. The introduction of mineral fertilizers in a dose of N60P60K60 under pre-sowing tillage significantly increased the soil biological activity in comparison to the unfertilized background, and a fairly high intensity of flax decomposition was observed in the second rotation of crops with 24.9% in 45 days and 56.8% in 90 days. Correlation analysis (1998-2019) between the mean flax decomposition under crops for the entire vegetation period and the value of the hydrothermal coefficient (HThC) showed a close direct correlation, which in the first and second periods of exposure was 0.87–0.90 and 0.86–0.89, respectively.
#AbolishNCR: A Qualitative Analysis of Social Media Narratives around the Insanity Defense
Authors: Goossens Ilvy , Jordan Marlee , Nicholls Tonia
Published: September 2021

This article presents an analysis of social media posts by laypersons regarding a finding of Not Criminally Responsible on Account of Mental Disorder (NCRMD) for Matthew de Grood after a high-profile trial in 2016 in Canada. From trial to verdict, a total of 4,991 tweets relating to the case were harvested from Twitter. Qualitative content analysis of 365 tweets by laypersons revealed three themes – largely equating the insanity defense to a legal loophole: (1) The case exemplified a misappropriation of the legal defense (e.g., due to privilege, due to the seriousness of the offence); (2) The perception existed that the NCRMD defence is a miscarriage of justice; (3) Many comments reflected a search for answers and justice. These embodied the ABCs of NCRMD: advocating, blaming, and clarifying. A need for public education about the forensic psychiatric system is evident; misconceptions about the insanity defence appeared pervasive. Further research could focus on the efficacy of knowledge translation over new media channels, such as Twitter.
Can Multilingualism Be a Radical Force in Contemporary Canadian Theatre? Exploring The Option of Non-Translation
Authors: Karpinski Eva C.
Published: September 2021

Recognizing the richness of multilingual theatre in Canada, this article argues that the choice of nontranslation as the absolute staging of multilingual hospitality carries the promise of a more radical cohabitation and offers both critical and reparative encounters with bodies that resist mainstream recuperation. Beyond multicultural accommodation of diversity, non-translation as a politicized choice is examined through examples chosen from contemporary Asian Canadian and Afro-Caribbean Canadian drama, as well as Indigenous performance. Specifically, the article analyzes the deployment of multilingualism “from below” (Alison Phipps’s term) in front of mainstream Anglophone audiences in such plays as debbie young and naila belvett’s yagayah.two.womyn.black.griots, Betty Quan’s Mother Tongue, and Monique Mojica’s Chocolate Woman Dreams the Milky Way. The decolonial practice of non-translation embraced by these playwrights contributes to the trend of “diversifying diversity” and promotes more balanced linguistic ecologies. Rather than softening the hard edges of difference in a global spread of equivalences, multilingualism “from below,” associated with minoritized languages and invisibility, embraces radical heterogeneity and incommensurability, radically confronting the meaning of ethnicized, hyphenated multiculturalism. However, at the same time, these forms of multilingualism throw into high relief the selective cultural politics of translation that privileges Canada’s official bilingualism
SIRT1 gene polymorphism and its plasma concentration in men with no signs of cardiovascular pathology, residents of Podilia region of Ukraine
Authors: Kalinovskaya T. M. , Donets A. O. , Zhebel V. M.
Published: September 2021

Annotation. The aim of the work – on the basis of scientific literature to consider the current state of prediction and diagnosis of hypertension using biomarkers. A review analysis of literature sources of domestic and foreign authors on the polymorphism of the SIRT1 gene and the possibility of using data of the biomarker SIRT1 in the diagnosis and treatment of patients with cardiovascular pathology and the concentration of SIRT1 in the blood plasma of 79 practically healthy men, 40-60 years old, residents of the Podilia region of Ukraine with carriers of polymorphic SIRT1 genes, genotype GG, CC and CG was studied. The concentration of SIRT1 in the blood plasma of the examined men was determined by enzyme-linked immunosorbent assay. Genotyping of the SIRT1 gene was performed by polymerase chain reaction. Processing of the obtained results was performed using STATISTICA 6.0. Practically healthy men from the Podilia region of Ukraine are dominated by variants of the CC and CG genotypes. The concentration of SIRT1 in the blood plasma of men, residents of the Podilia region of Ukraine without signs of cardiovascular pathology is not associated with polymorphism of variants of the coding gene SIRT1. It is planned to use the obtained results for further study of SIRT1 concentration in carriers of polymorphic genes in men with stage I and II hypertension, which may have diagnostic value.
Paraoxonase in women with hypertension of different reproductive age. Relationship with cardio-metabolic risk factors
Authors: Pentiuk L. O. , Pentiuk N. O.
Published: September 2021

Annotation. Paraoxonase is a high-density lipoprotein-associated pleiotropic enzyme able to detoxify proatherogenic compounds such as oxi-low-density-lipoproteins and homocysteine-thiolactone. Low paraoxonase activity is likely to be involved in the development of cardiovascular diseases. The aim of the study – to investigate the relationship between paraoxonase activity, structural and functional markers of the heart and blood vessels, cardio-metabolic risk factors in women with hypertension of different reproductive age. The study included 193 women aged 32-70 years (55.4±0.68 years) with essential stage II hypertension. The control group consisted of 46 healthy women. The arylesterase activity of paraoxonase (EC 3.1.1.2) in blood serum was determined by spectrophotometric method. Statistical processing of the obtained results was performed in the application package SPSS22 (© SPSS Inc.). The mean and standard error of the mean (M ± m) were calculated. Student's t-test was used. Pearson correlation analysis was performed at p <0.05. It was found that in women with hypertension there was a significant decrease (16%) in serum paraoxonase activity, compared with healthy women. Low paraoxonase activity was registered in 33.3% of premenopausal patients and 56.7% of postmenopausal patients (p˂0.05) and was associated with serum estradiol levels (r=0.33, 0.41, p<0.05). Low paraoxonase activity was associated with aberrant levels of lipids, homocysteine, obesity, metabolic syndrome, increased left ventricular mass index and carotid intima-media thickness, decreased brachial artery endothelium-dependent vasodilation. Thus, the decrease in serum paraoxonase activity in women with hypertension is related with the reproductive age of patients and the development of unfavorable metabolic, structural and functional changes in the heart and blood vessels.
The state of the problem of fractures of the distal metepiphysis of the humerus in children and adolescents
Authors: Guriev S. O. , Trutiak I. R. , Obaranets O. V.
Published: September 2021

Annotation. One of the most frequent injuries of the distal end of the humerus is the trans-condylar and supracondylar fractures of the humerus, which make up 47.5-80% of all intraarticular fractures of the elbow joint in children. Among the injuries of the distal humerus, the supracondylar and supracondylar fractures occur with the greatest frequency and is one of the most common domestic injuries in children aged 3 to 12 years. Our work is based on a retrospective analysis of the treatment of 255 patients treated in the Lviv City Children's Hospital for the period 2013-2017. 83.1% of patients were diagnosed with flexion fracture, 16.9% – flexion fracture. Transvertebral fractures of the shoulder were diagnosed in 85.5% of cases of the study array, supragingival – in 14.5%. The treatment of patients with the consequences of injuries of the elbow joint presents great difficulties and remains one of the most difficult problems in pediatric traumatology. Depending on the presence of rotational displacement and the severity of the fracture, the following types of treatment are most often used: conservative, osteosynthesis with spokes or Ilizarov apparatus. An ideal reposition and stable fixation of fragments during these injuries is necessary not only to ensure timely consolidation of the fracture, restoration of the anatomical integrity and shape of the distal humerus, but also to prevent the development of deformation in the elbow joint. Deformations of the elbow joint during supracondylar and supracondylar fractures of the shoulder, unlike deformation of another localization, cannot be adjusted and subsequently only increase and as a result can lead to impaired function of the elbow joint, and often to disability already in childhood. Thus, complicated anatomical localization of supracondylar and supracondylar fractures of the humerus in children, great technical difficulties in comparing and fixing fragments, there is a high probability of neurological and vascular disorders, both at the time of injury and during the provision of medical care, impaired function of the elbow joint determine the need for further study of this problem.
Correction of cardioesophageal transition as a stage of treatment after endoscopic welding of esophageal metaplasia
Authors: Tyselskyi V. V. , Kebkalo A. B.
Published: September 2021

Annotation. Barrett’s esophagus is an acquired condition that develops as a result of the replacement of normal stratified squamous epithelium in the lower part of the esophagus by columnar epithelium. Barrett’s esophagus is considered a complication of gastroesophageal reflux disease (GERD). It has been shown and proven that various endoscopic methods are successful in treating this condition. However, long-term success in preventing further metaplasia and dysplasia is incompletely studied. Biological welding – controlled action of high frequency current on living tissues. It is used to stop gastrointestinal bleeding, ablation of small intestinal metaplasia of the esophageal mucosa. The aim of this study was to evaluate the success of endoscopic treatments for Barrett's esophagus and the need for further surgery in patients with GERD complicated by Barrett’s esophagus. Patients with Barrett’s esophagus C1-3M2-4 (Prague classification 2004) and severe dysplasia without nodule, as well as confirmed GERD without esophageal hernia were included. A total of 98 patients were included in the study, of whom 89 were re-consulted and examined after primary Barrett's esophageal ablation. Endoscopic treatment was performed by argon-plasma coagulation (APC) and high-frequency welding of living tissues (HFW). In the dynamics of patients were re-examined. Patients with recurrent metaplasia and a high DeMeester index (˃100) underwent antireflux surgery – crurography (if necessary) and Nissen fundoplication with a soft and short cuff. Recurrence of small bowel metaplasia was recorded in 15 patients. 12 patients underwent a two-stage treatment: first a second session of esophageal ablation, and in the second stage - antireflux surgery. 2 patients refused surgical treatment and underwent only the second session of ablation. All patients received drug therapy – prokinetics and proton pump inhibitors. Three months after surgery, pH metry was performed again, which showed normalization of the DeMeester index, as a result of which patients had no complaints such as heartburn, chest pain, dysphagia, which significantly improved their quality of life. Esophagogastroduodenoscopy and biopsy of the mucous membrane of the lower third of the esophagus according to the Seattle protocol was also performed. After examination of the histological material of metaplasia zones were not recorded. It is concluded that antireflux surgery is required as part of Barrett’s esophageal treatment to prevent further dysplasia and the development of esophageal cancer.
Investigation of the influence of gravel stuffing in an open drill on the productive characteristics of the well
Authors: Kondrat R. М. , Dremliukh N. S. , Haidarova L. І.
Published: September 2021

The negative consequences of sand production from the formation into the wellbore during the operation of wells with unstable rocks are characterized. A highly effective method of preventing sand from entering the well from the formation is the use of gravel packs, which are used in Ukraine and abroad. The types of gravel packs, the conditions for their application, the choice of the diameter of gravel grains for creating gravel pack are given. The types of gravel pack installation are considered depending on the geological and technical conditions of the reservoir. Calculations have been performed using Schlumberger's PipeSim software to assess the effect of gravel pack size and permeability on the performance specification of a gas well. Based on the research results, graphical de-pendences of gas flow rates in the presence of gravel pack on the permeability of the gravel pack at its various thicknesses have been constructed and analyzed. It has been found that the gas flow rate increases with an increase in the thickness of the gravel pack in the considered interval of its variation up to 0.9 m. The effect of the thickness of the gravel pack on the gas flow rate increases with an increase in its permeability. Based on the results of statistical processing of the calculated data using the least-squares method, the optimal values of the gravel pack permeability for various values of its thickness have been determined. The optimal values of the thickness and permeability of the gravel pack have been determined, beyond which the value of the gas flow rate practically does not change. The calculation of the pressure distribution along the bore of a gas well in the presence of gravel pack with certain optimal values of its permeability and thickness is performed. Using the PipeSim software, the influence of the de-gree of relative formation penetration on the productivity of a gas well in the presence of gravel packing has been investigated for determining certain optimal values of permeability and thickness of gravel packing.
PROBABILISTIC APPROACH TO MEASURING PRICE RISK OF THE ENTERPRISE
Authors: Ivan MAKARCHUK , Iryna FEDULOVA
Published: September 2021

Background. Every manager faces analyzing problem and forecasting indicators in the process of making management decisions that are random variables, and therefore they are associated with risk and uncertainty. Their realization is possible in the future, but today we need to understand the risk level that can be encountered in the activity process and prepare for it in advance. Analysis of recent research and publications has shown that probabilistic approach is the most commonly used tool for risk assessment and it is based on probability theory. The aim of the article is to consider the tools of the probabilistic approach to riska ssessment. According to this approach, risk assessment is carried out for products price that have a normal law distribution and for which we can use an integrated probability distri­bution function and the key indicators that underlie its structure. Materials and methods. The methodological basis of risk analysis by the probabilistic approach is the consideration of the initial data as expected values of some random variables with known laws of probability distribution. Results. The use of tools of probabilistic approach to risk assessment of product pricing is considered. It is based on the assumption that a normal probability distribution law, an integral probability distribution function, and the key indicators that underlie its construction can be used to analyze market price risk. Conclusion. Probabilistic approach allows with minimal effort to understand the probability of obtaining the desired result, which is related to the purpose of the enterprise, or which result can be obtained with the desired probability and determine their acceptability. Keywords: risk, risk analysis, risk assessment, probabilistic approach, integral pro­bability distribution function.
MANAGEMENT OF CONSUMERS BEHAVIOR OF HOSPITALITY SERVICES
Authors: Mariia KULYK , Kateryna KOMPANETS , Oksana AVDAN
Published: September 2021

The article considers the consequences of the Covid-19 pandemic on the activities of hospitality enterprises. The main determinants that changed consumer behavior under quarantine restrictions were identified. It was determined that scientific works did not study methods of researching consumer loyalty in crisis conditions. This gave reason to establish the purpose and objectives of the article and to prove the need to apply the proposed universal method of identifying consumer satisfaction level with hospitality services. Keywords: hospitality enterprises, consumer, consumer satisfaction level, con­su­mer behavior, the Covid-19 pandemic.
Novel Approach to Treating Acute Hamstring Injury- Effects of Primal Reflex Release Technique
Authors: Bianco Lucas , May James , Nasypany Alan
Published: September 2021

Hamstring injuries have an occurrence rate of 3.05 per 1000 athlete exposures in intercollegiate athletics. Current clinical practice recommendations for rehabilitation of hamstring injuries are based on pathoanatomical muscle tissue healing timeframes. The purpose of this study was to examine the effects of modulating the nervous system with Primal Reflex Release Technique (PRRT) in patients clinically diagnosed  with functional neuromuscular hamstring muscle-related disorder (FNHD). In this a priori case series , PRRT was utilized in four patients participating in intercollegiate, National Collegiate Athletic Association Division II, athletics to evaluate Numeric Pain Rating Scale (NRS) for current pain, Disablement of the Physically Active (DPA) scale, modified Patient Specific Functional Scale (PSFS), and Active Knee Extension Test (AKET). The initial pre-treatment to post-treatment average difference for NRS (3.25±2.5 points) and AKET (11±2.16°) improved by an amount that satisfied MCID and MCD respectively. The pre-treatment to one-week  follow-up average difference for NRS (5.5±2.3 points), PSFS (4.75±2.5 points), and AKET (20.5±14°) improved by an amount that satisfied MCID or MCD. The average timeline for discharge to full unrestricted activity was 2.75 days. In the four patients classified with a functional neuromuscular muscle disorder,  PRRT was utilized as the only manual therapy intervention. Through modulation of the nervous system, the outcomes reported by the patients were both meaningful and clinically significant. Based on the results and the current standard of care for similar patients , the need for further research into this paradigm is warranted. Hamstring injuries continue to be a significant clinical injury in the athletic patient population. A thorough evaluation and appropriate classification of muscle injury can help clinicians decided an effective treatment for the patient. Clinicians seeking to improve patient outcomes may benefit from considering a paradigm that modifies the neural allostatic loads.
Features of the geological structure of an oil and gas condensate field in Tomsk region
Authors: Mulyavin S. F. , Byakov A. V. , Neschadimov R. A.
Published: September 2021

The X oil and gas condensate field is located in Parabel district of Tomsk region; the field is large in terms of recoverable reserves. Oil and gas content is confined to Jurassic sediments of Tyumen suite and Vasyugan suite. The reservoirs of the Vasyugan suite are marine and coastal-marine sediments, characterized by alternating sandstones, mudstones, siltstones, clays and exhibit complex internal aging. The productive deposits of the Tyumen suite are of continental origin and are distinguished by significant lithological variability. One oil deposit (J11 stratum), one gas and oil deposit (J12 stratum) and three gas condensate deposits (J13-4, J3, J4-5 strata) were identified in the productive formations. The article analyzes the features of the geological structure and conditions of sedimentation of productive strata. In terms of its phase state and physicochemical proper-ties, the fluid of the J11 deposit is a "volatile oil", phase state of which is close to the near-critical. Reservoirs of productive formations are of terrigenous type, porous, low-permeability, while the oil productivity of the formations is high due to the ultra-low oil viscosity.
The use of data on capillary pressures in the development of deposits in the Middle Ob region
Authors: Sabanina I. G. , Semenova T. V. , Bolshakov Yu. Ya. , Vorobjeva S. V.
Published: September 2021

Currently, most of the oil fields in the West Siberian oil and gas province are in the final stage of development. There is water-cut in production, a decrease in oil production, and the structure of residual reserves deteriorates. The search and application of the most successful scientific methods and technologies for improving oil recovery in the development of fields is quite an urgent task.

It should be taken into account that hydrophobic reservoirs are common in the oil fields of Western Siberia, and when applying the method of reservoir flooding, this fact should be taken into account and a more detailed approach should be taken to the study of capillary forces to prevent flooding of productive objects. Despite the good knowledge of the West Siberian megabasin, some fundamental issues of its structure and oil and gas potential remain debatable.

The article proposes methods for improving oil recovery of the BS10 formation of the Ust-Balykskoye oil field based on the study of capillary pressures in productive reservoir formations, and provides recommendations for the placement of injection wells. The study of the capillary properties of reservoir rocks will significantly improve the efficiency of exploration and field operations in oil fields.
Predictive estimates of subsidence of the earth’s surface during the development of the Yamburgskoye oil and gas condensate field
Authors: Vasiliev Yu. V. , Mimeev M. S. , Misyurev D. A.
Published: September 2021

The production of hydrocarbons is associated with a change in the physical and mechanical properties of oil and gas reservoirs under the influence of rock and reservoir pressures. Deformation of the reservoir due to a drop in reservoir pressure leads to the formation of various natural and man-made geodynamic and geomechanical phenomena, one of which is the formation of a subsidence trough of the earth's surface, which leads to a violation of the stability of field technological objects.

In order to ensure geodynamic safety, a set of works is used, which includes analysis of geological and field indicators and geological and tectonic models of the field, interpretation of aerospace photographs, identification of active faults, construction of a predictive model of subsidence of the earth's surface of the field with identification of zones of geodynamic risk.

This work was carried out to assess the predicted parameters of rock displacement processes during field development; even insignificant disturbances in the operation of technological equipment caused by deformation processes can cause significant damage.

Prediction of rock displacements is possible only on the basis of a reservoir deformation model that adequately reflects the geomechanical and geodynamic processes occurring in the subsoil. The article presents a model of reservoir deformation with a drop in reservoir pressure, describes its numerical implementation, and performs calculations of schemes for typical development conditions.
Characterization of patient-derived bone marrow human mesenchymal stem cells as oncolytic virus carriers for the treatment of glioblastoma
Authors: Shimizu Yuzaburo , Gumin Joy , Gao Feng , Hossain Anwar , Shpall Elizabeth J. , Kondo Akihide , Parker Kerrigan Brittany C. , Yang Jing , Ledbetter Daniel , Fueyo Juan , Gomez-Manzano Candelaria , Lang Frederick F.
Published: September 2021

OBJECTIVE

Delta-24-RGD is an oncolytic adenovirus that is capable of replicating in and killing human glioma cells. Although intratumoral delivery of Delta-24-RGD can be effective, systemic delivery would improve its clinical application. Bone marrow–derived human mesenchymal stem cells (BM-hMSCs) obtained from healthy donors have been investigated as virus carriers. However, it is unclear whether BM-hMSCs can be derived from glioma patients previously treated with marrow-toxic chemotherapy or whether such BM-hMSCs can deliver oncolytic viruses effectively. Herein, the authors undertook a prospective clinical trial to determine the feasibility of obtaining BM-hMSCs from patients with recurrent malignant glioma who were previously exposed to marrow-toxic chemotherapy.

METHODS

The authors enrolled 5 consecutive patients who had been treated with radiation therapy and chemotherapy. BM aspirates were obtained from the iliac crest and were cultured to obtain BM-hMSCs.

RESULTS

The patient-derived BM-hMSCs (PD-BM-hMSCs) had a morphology similar to that of healthy donor–derived BM-hMSCs (HD-BM-hMSCs). Flow cytometry revealed that all 5 cell lines expressed canonical MSC surface markers. Importantly, these cultures could be made to differentiate into osteocytes, adipocytes, and chondrocytes. In all cases, the PD-BM-hMSCs homed to intracranial glioma xenografts in mice after intracarotid delivery as effectively as HD-BM-hMSCs. The PD-BM-hMSCs loaded with Delta-24-RGD (PD-BM-MSC-D24) effectively eradicated human gliomas in vitro. In in vivo studies, intravascular administration of PD-BM-MSC-D24 increased the survival of mice harboring U87MG gliomas.

CONCLUSIONS

The authors conclude that BM-hMSCs can be acquired from patients previously treated with marrow-toxic chemotherapy and that these PD-BM-hMSCs are effective carriers for oncolytic viruses.
Posługa charyzmatyczna jako implikacja nowej ewangelizacji na przykładzie Kościoła w Polsce
Authors: Brożyna Paweł Władysław
Published: September 2021

Podstawową misja Kościoła jest doprowadzenie człowieka do przyjęcia Jezusa Chrystusa jako swojego Pana i Zbawiciela. Służyć ma temu szeroko pojęta ewangelizacja. Wielu wskazuje, że obecnie Kościół przeżywa kryzys. Wydaje się, że zjawisko sekularyzacji zbiera największe dotychczas żniwo. Równolegle obserwuje się coś odwrotnego. Tysiące ludzi w Polsce i na całym świecie odnajduje się na nowo w Kościele. Bez wątpienia dzieje się tak za sprawą nowej ewangelizacja, która jest owocem Soboru Watykańskiego II. Szczególna rolę w tym dziele odgrywają dary duchowe zwane charyzmatami, które są dane przez Ducha Świętego. Wraz z nimi zauważalne jest posługa charyzmatyczna, która gromadzi liczne rzesze ludzi potrzebujących i szukających Bożej Obecności i Bożego działania. Dzięki tej posłudze i wielkiej roli nowych wspólnot przeżywamy obecnie wiosnę Kościoła.
Teologia czułości papieża Franciszka i jej dwudziestowieczne filozoficzno-teologiczne antecedensy
Authors: Surmiak Wojciech Tadeusz
Published: September 2021

Teologia moralna nie poświęciła jak dotąd w swojej historii wiele miejsca zagadnieniu czułości. Wystarczy rzucić okiem do najpopularniejszych słowników teologii moralnej, aby stwierdzić albo całkowitą nieobecność, albo jedynie marginalną obecność tej problematyki, czy to w nauczaniu doktrynalnym, czy chociażby w katalogu cnót. W niniejszym artykule zostaną ukazane niektóre dwudziestowieczne próby filozoficznego i teologicznego zmagania się z zagadnieniem czułości, które stanowiły niejako wprowadzenie do zaproponowanej przez papieża Franciszka teologii czułości. Zostaną także ukazane sposoby rozumienia czułości w teologii Franciszka oraz jej egzystencjalne przykłady. Papież Franciszek, wydaje się rozumieć czułość jako sposób egzystencji i relacji z drugim człowiekiem, który współgra ze sposobem bycia chrześcijaninem w świecie, ponieważ jest to sposób ukazania Boga światu. Ten sposób życia charakteryzuje się empatyczną bliskością, egzystencją na sposób daru z siebie, realnym uczestnictwem w życiu drugiego człowieka w jego radościach i cierpieniach, i w końcu, w ojcowskim i macierzyńskim zatroskaniu. Wedle miary, w której teologia moralna ma jako swój przedmiot ukazanie autentycznej egzystencji ludzkiej w konkretnych miejscach życia człowieka, trzeba powiedzieć, że po nauczaniu Franciszka nie jest możliwym uprawianie teologii moralnej, która abstrahuje od czułości jako centralnej cnoty w realizacji chrześcijańskiego powołania.
Pobożność ludowa jako kontekst mariologii J.M. Bergoglio /papieża Franciszka
Authors: Bujak Janusz
Published: September 2021

Celem artykułu jest ukazanie kontekstu, w jakim kształtowała się duchowość maryjna i mariologia papieża Franciszka. Artykuł w pierwszym paragrafie przyczyny maryjnego charakteru pobożności wiernych w Ameryce Łacińskiej, których należy szukać w samych początkach ewangelizacji Nowego Świata. Drugi paragraf ukazuje etapy kształtowania się teologii i duchowości maryjnej przyszłego papieża, począwszy od domu rodzinnego aż do momentu święceń biskupich w 1992 r. W kolejnym paragrafie zostały przedstawione główne tezy mariologiczne zawarte w dokumentach końcowych Konferencji CELAM. Czwarty paragraf koncentruje się na Dokumencie z Aparecidy i jego analizie, której dokonał kard. Bergoglio w rok po jego publikacji. Piąty i ostatni paragraf prezentuje obecność mariologii południowoamerykańskiej, zwłaszcza Dokumentu z Aparecidy, w adhortacji papieża Franciszka Evangelii gaudium. Z przeprowadzonych badań można wyciągnąć wniosek, że mariologia papieża Franciszka ma wymiar charakter przede wszystkim kerygmatyczny, eklezjotypiczny i funkcjonalny.
JUDAIZM I EKONOMIA. ZWIĄZEK JUDAIZMU Z ŻYCIEM GOSPODARCZYM
Authors: Fel Stanisław , Zdun Magdalena
Published: September 2021

Artykuł podejmuje tematykę związku judaizmu z szeroko rozumianą aktywnością gospodarczą. Przedmiotem rozważań jest typowe dla etyki żydowskiej rozumienie pieniądza, bogactwa, pracy i gospodarczych inicjatyw. Fundamentalne dla życia gospodarczego kwestie ujęte zostają w odniesieniu do ksiąg uznanych za święte i szczególnie ważne w tej religii (Stary Testament, Talmud). Równie ważne są referencje do kulturowych interpretacji judaizmu, w tym do dzieł klasyków tematyki – Jacquessa Attaliego czy Wernera Sombarta. Kluczowym dla tematyki pojęciem jest „bogactwo”, którego znaczenie zostaje wyprowadzone kolejno z Biblii (Księga Wyjścia) i Talmudu. Ostatecznie ekonomika żydowska daje się przedstawić jako wytwór kultury osadzonej i ufundowanej na religii, a majątek zyskuje etyczną legitymizację. Wywód wieńczą historyczne przykłady aktywności gospodarczej Żydów, będące jednocześnie dowodem na wzajemne powiązania bogactwa i religii.
TOMASZ ZARĘBSKI, NEOPRAGMATYZM ROBERTA B. BRANDOMA, TOWARZYSTWO AUTORÓW I WYDAWCÓW PRAC NAUKOWYCH UNIVERSITAS, KRAKÓW 2013, 378 s.
Authors: Kublikowski Robert
Published: September 2021

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Kontradyktoryjność postępowania apelacyjnego – wybrane zagadnienia
Authors: Rzewuski Maciej
Published: September 2021

Na gruncie poszczególnych gałęzi prawa wyróżnia się tzw. naczelne zasady prawa, będące odzwierciedleniem podstawowych założeń danej dziedziny prawa. Do takich zasad na gruncie postępowania cywilnego, zaliczana jest zasada kontradyktoryjności. W najbardziej ogólnym ujęciu oznacza ona obciążenie stron procesowych ciężarem przytaczania okoliczności faktycznych i zgłaszania dowodów na ich poparcie. Kognicja sądu cywilnego, w myśl tej zasady, sprowadza się jedynie do oceny zaoferowanego przez strony materiału dowodowego i wydania na tej podstawie stosownego rozstrzygnięcia. Wprowadzenie zasady kontradyktoryjności powinno w sposób odczuwalny przyczynić się do stworzenia szybkiego i efektywnego mechanizmu służącego do wymierzania sprawiedliwości na podstawie materiału dowodowego zaoferowanego przez strony. Nagrodą za należyte wywiązanie się z nałożonego ustawą obowiązku wykazania swoich racji, winno być wygranie procesu.
Giustizia e diritti
Authors: Tafaro Sebastiano
Published: September 2021

La proclamazione di diritti senza contestuale strumenti che ne assicurino l’effettività è fonte di crisi de diritto e della Giustizia. Occorre proporre un nuovo ‘modello’, per il quale il diritto ed il processo romano appaiono fonte di suggestioni e di spunti innovativi applicabili anche all’oggi. In particolare è inammissibile l’enfatizzazione dei ‘Trattati’ sino al punto di minacciare l’uomo e l’ambiente. Il diritto romano indica la via per impedire l’assoggettamento agli interessi economico- finanziari di pochi.
Mediación policial y tutela judicial efectiva en la actualidad: reflexiones de una romanista
Authors: Guillamón Carmen Lázaro
Published: September 2021

No se duda de que el derecho a la tutela judicial efectiva es clave en la conformación del Estado de Derecho, pero también ha impedido la posibilidad de establecer formas de justicia extrajudicial a las que se apela en los últimos tiempos como fórmula de salvación para una Justicia enferma. El estudio de esta cuestión requiere un análisis histórico de las fuentes jurídicas romanas, este será el marco histórico que fundamenta desde un punto de vista dogmático la actividad de la Policía como gestora de conflictos. Así, se pondrá de relieve la importancia del método de los juristas romanos y del trabajo del Pretor –magistrado jurisdiccional- no sólo como antecedentes históricos, sino como elementos esenciales en la configuración del Sistema de Administración de Justicia en el que la mediación ha de ser tratada como uno de sus instrumentos.
Ne eat iudex ultra petita partium od prawa rzymskiego do czasów współczesnych. Uwagi na tle polskiego procesu cywilnego
Authors: Laskowska-Hulisz Agnieszka
Published: September 2021

Zasada ne eat iudex ultra petita partium, czyli niech nie wychodzi sędzia ponad żądania stron ujmowana jest współcześnie jako zakaz orzekania przez sąd ponad żądanie. Zasada ta nie znajduje dosłownego potwierdzenia w tekstach prawa rzymskiego. Pochodzi ona z późniejszych opracowań nawiązujących do tego prawa. W prawie współczesnym sentencja ta jest wyrazem jednej z podstawowych i zarazem najważniejszych zasad orzekania oraz gwarancją realizacji w procesie cywilnym zasady dyspozycyjności. Zasada ta bowiem wskazuje na to, że uprawnienie do wszczęcia procesu cywilnego oraz do wyznaczenia granic poszukiwanej ochrony prawnej przysługuje uprawnionemu podmiotowi. Co z kolei wyraża się w tym, że sąd nie może wszcząć procesu bez wniosku (pozwu) strony, nie może orzekać co do przedmiotu, który nie był objęty żądaniem ani zasądzać ponad żądanie. W celu omówienia tytułowego zagadnienia w artykule przybliżono w pierwszej kolejności genezę tej zasady, następnie ewolucję historycznoprawna polskiej regulacji prawnej odnoszącej się do tej zasady, aby w końcu krótko przedstawić kształt, jaki tej zasadzie nadał ustawodawca polski w kodeksie postępowania cywilnego.
Przyznanie się oskarżonego do winy w rzymskim procesie karnym
Authors: Chmiel Andrzej
Published: September 2021

Przyznanie się oskarżonego do winy przez cały okres republiki aż do II wieku n.e. było traktowane jako wystraczająca podstawa do wydania skazującego wyroku w rzymskim procesie karnym. Takie postępowanie było przede wszystkim wynikiem tego, iż czyn sprawcy postrzegano tylko z punktu widzenia jego skutków, a nie motywacji oskarżonego. Dopiero w okresie cesarstwa confessio zostało poddane kontroli początkowo samego cesarza, a następnie jego urzędników. W czasach pryncypatu sędzia, w którego rolę wcielał się cesarski urzędnik, został wyposażony w stosowne narzędzie, które miało umożliwić mu dotarcie do prawdy. Tym ostatnim stały się tormenta. Wydaje się, iż to właśnie pojawienie się tortur wymusiło zwłaszcza na rzymskiej jurysprudencji zainteresowanie, zarówno problematyką zawinienia sprawcy czynu, ale także, psychologiczną oceną wiarygodności jego wyjaśnień. W efekcie, to tormenta doprowadziły do tego, iż przyznanie się do winy przestało być traktowane w rzymskim procesie karnym jako regina probationum.
Efektywność prawa umów. Rola sądów
Authors: Szczerbowski Jakub
Published: September 2021

Efektywność prawa umów leży w centrum zainteresowania stron umowy, w szczególności w przypadku umów pomiędzy profesjonalistami. Pomimo tego, litera prawa rzadko odnosi się do efektywności jako kategorii prawnej. Organizacja i funkcjonowanie wymiaru sprawiedliwości wpływa na koszty transakcyjne stosunków umownych. Ten wpływ można podzielić na dwie szerokie kategorie, wpływ niestabilności lub rozbieżności w orzecznictwie i wpływ dostępu do wymiaru sprawiedliwości. Powszechnie uznaje się, że stabilność orzecznictwa wpływa pozytywnie na dostęp do wymiaru sprawiedliwości poprzez zmniejszanie pobudek do wytaczania powództw. Odmienny pogląd proponuje E. Posner w eksperymencie myślowym, w którym rażąco niekompetentne sądy mają mimo wszystko prowadzić do wykonania umowy przez strony – poprzez wywołanie w stronach umowy niechęci do procesu. W niniejszym tekście przeprowadzono polemikę z powyższym poglądem kwestionując zarówno jego założenia jak i jego wiarygodność w stosunku do obserwacji rzeczywistości.