bluuebunny/crossref_metadata_2025 huggingface dataset:
FEATURES OF VEGETATIVE REGULATION OF HEART RHYTHM, PERIPHERAL BLOOD AND HORMONAL PROFILE IN ADOLESCENTS OF STAVROPOL REGION: ETHNOPHYSIOLOGICAL ASPECTS
Authors: Agadzhanyan N A , Tsaturian L , Kuvandykova R H
Published: June 2022

A comprehensive multi-stage expedition study of healthy adolescents from different ethnic groups of the Stavropol Territory has been carried out. On the basis of the heart rate variability data, there has been determined dominant influence of the sympathetic nervous system, expressed stress and strain of the regulatory systems in the adolescents, which were more developed in the Russian girls. Taking into account ethnic differences, there have been revealed qualitative and quantitative differences between the basic parameters of the peripheral blood, characterized by a relative increase in the level of red blood cells and hemoglobin in the Russian schoolchildren, a large volume of red blood cells in the Turkmen girls and the largest amount of platelets in the Turkmen boys. The level of these hormones in the groups of the adolescents of different nationalities was within the age norm, with higher cortisol values observed in the Russian adolescents of both sexes, what indicated a higher tension of adaptation mechanisms in the group of the Russian schoolchildren. Concentration of sex hormones in the blood serum was higher in the Russian boys and the Turkmen girls. Identified variations of the studied parameters were probably caused by influence of natural-climatic factors on the body, as well as by specificity of metabolic regulation of the growing organism and the adolescents' ethnicity.
PREVALENCE OF ANEMIA, ITS SOCIO-DEMOGRAPHIC DETERMINANTS AND POTENTIAL ASSOCIATION WITH METABOLIC SYNDROME IN RESIDENTS OF TURKESTAN, SOUTHERN KAZAKHSTAN
Authors: Sadykova K Zh , Shalkharova Zh S , Shalkharova Zh N , Nuskabayeva G O , Sadykova А D , Zhunissova M B , Madenbay К M , Grjibovski A M
Published: June 2022

We have studied the prevalence and socio-demographic determinants of anemia and also have investigated associations between anemia and metabolic syndrome in Turkestan, Southern Kazakhstan region, Kazakhstan. Southern Kazakhstan is one of the regions with the lowest level of incomes. The sample consisted of 839 patients from the polyclinic of the International Kazakh-Turkish University. The overall prevalence of anemia was 26.4 %. The highest prevalence of anemia was observed among women (30.4 %) and in the age group 30-39 years (39,0 %). A multiple logistic regression was performed to study independent associations between the studied factors and development of anemia with and without adjustment to other socio-demographic factors. The odds of anemia in persons from the oldest age category is 5 times lower than in the younger age categories. Odds of anemia in men by 2.4 times less compared to women. A multiple linear regression was used to study associations between hemoglobin levels and socio-demographic factors. There were statistically significant relationship between hemoglobin levels and age (β = 5.85; 95 % CI: 1.63; 10.06), between hemoglobin level and gender (β = 21.50; 95 % CI: 19.12 ; 23.89). Also, was found statistically significant interaction between the presence of metabolic syndrome and the level of hemoglobin after adjustment for all socio-demographic factors ((β = 3.12; 95 % CI: 0.53; 1.32).
PSYCHOEMOTIONAL STRESS AND EATING BEHAVIOR IN KAZAKHSTAN
Authors: Zhunissova M B , Shalkarova Zh S , Shalkarova Zh N , Nuskabayeva G O , Sadykova K Zh , Madenbay K M , Grjibovski A M
Published: June 2022

The aim of this study was to assess the level of psychoemotional stress and its association with eating behavior in the town of Turkestan, Southern Kazakhstan. Turkestan region is considered as one of the most unfavourable regions in Kazakhstan with poor ecologic conditions. Altogether, 637 individuals from the population served by the policlinic of the International Kazakh-Turkish University participated in a cross-sectional study. The level of stress was assessed using the Perceived Stress Scale-10 questionnaire. Eating behavior was assessed using the Dutch Eating Behaviour Questionnaire. Multinomial logistic regression models and multivariable linear models were applied to study associations between stress and eating behavior. The prevalence of light, moderate and intensive stress was 38.5 %, 50.2 % and 11.3 %, respectively. The prevalence of restrictive, emotional and external types of eating behavior was 30.3 %, 37.5 % and 32.2 %, respectively. We observed positive and statistically significant association between the level of stress and external type of eating behavior. Moreover, eating behavior was also associated with gender, age and education.
ESTIMATION OF HEALTH RISK FACTORS PERCEPTION BY MEDICAL WORKERS
Authors: Dubel E V , Unguryanu T N
Published: June 2022

The cross-sectional epidemiological study has been performed to identify peculiarities of health risk factors perception by different categories of medical workers in the Vologda Hospital. Radioactive (91.4 %), chemical (87.6 %) and microbiological (73.7 %) pollution was perceived by the respondents as bringing the highest risk to health. The average risk factors included genetic and biological factors (61.7 %), emergency situations (58.8 %) and lifestyle factors (45.0 %). Physical and climatic factors and factors of life quality were perceived to be least hazardous. There were detected statistically significant differences in subjective perception of certain risk factors between doctors and nursing staff.
INFLUENCE OF SUBSTANCE πQ1983 ON ENERGY METABOLISM AND OXYGEN CONSUMPTION DURING ACUTE EXOGENOUS HYPOXIA
Authors: Sosin D V , Yevseyev A V , Pravdivtsev V A , Parfenov E A
Published: June 2022

The assessment of standard energy metabolism has been measured in rats after per os introduction of a new antihypoxic metal-complex substance πQ1983 with a dose 100 mg/kg. The well-known antihypoxant amthizole was used as a substance for comparison in the same dose. It had been established that 90 min after using πQ1983, activity of body energy processes decreased from 194.4 ± 0.7 kcal/day/kg (the control group) to 74.5 ± 0.5 kcal/day/kg (πQ1983), but the effect of amthizole was not reliable. It has also been revealed that both substances (πQ1983 significantly, amthizole slightly) decreased the rats' oxygen consumption rate during rising acute exogenous hypoxia that could increase the animals' resistance to the oxygen deficit. Probably, the decreased oxygen consumption was caused by the inhibitory effects of the studied substances, especially that of substance πQ1983, on body energy-intensive processes.
ATMOSPHERIC SUSPENSIONS OF RUSSKY ISLAND (VLADIVOSTOK) DURING THE 3-YEAR SUPERVISION (2011-2013)
Authors: Golokhvast K S , Nikiforov P A , Petukhov V I , Chayka V V
Published: June 2022

In this paper the results of research of particles of the atmospheric suspensions containing in a snow cover of the Russky Island (Vladivostok) first in the history of supervision, including in the territory of a Campus of Far East Federal University (seasons 2011/2012-2013/2014) are presented. Distribution of the particles of various sizes weighed in air and genesis in areas of the island differing with anthropogenous loading is revealed: campus of Far East Federal University, the bridge through the Eastern Bosphorus Strait and settlement the Channel. It is shown that in connection with increase of anthropogenous press of the Russky Island, its ecological state because of increase in the atmosphere of fractions nano - and microdimensional particles worsens.
CRYOTHERMAL TRAINING EFFECT ON STUDENT FUNCTIONAL CAPABILITY LEVEL IN EARLY TRAINING PERIOD
Authors: Mosyagin I G , Lobozova O V , Ivanov A O , Beskishkiy E N
Published: June 2022

Use of cyclic cryothermal influences in the mode (3-5 minute stay at the cryothermal chamber at -140...-160 °C 1 time per day, every other day, the total number of sessions 10) is an effective means of emergency and long-term expansion of the body functional capability in first-year students and cadets with difficulties of adaptation and acclimatization. The result of the method use was increased maximum volume of physical work performed, optimization of physical activity vegetation provision, acceleration of regeneration processes in the body. The data obtained allow to recommend widespread use of the method in the system of measures of physiological optimization of the process of professional integration of students, cadets and other categories of persons working in stressful conditions.
CORRELATION ANALYSIS USING STATA
Authors: Unguryanu T N , Grjibovski A M
Published: June 2022

International School of Public Health, Northern State Medical University Arkhangelsk, Russia *Department of International Public Health, Norwegian Institute of Public Health, Oslo, Norway In this paper we present general principles of correlation analysis and its use in biomedical research. Practical examples of correlation analysis are given. Calculations of Pearson’s and Spearmen’s correlation coefficients are presented using formulas and STATA software. Main assumptions for the use of correlation analysis are discussed as well as general principles of presentation of the results in biomedical publications. The article presents only general information about correlation analysis and does not substitute special statistical literature.
MENTAL ECOLOGY OF TERRORISTIC CIVIL WARS
Authors: Sidorov P I
Published: June 2022

In the article, there has been proved attribution of terrorism to polymodal dependent disorder. There has been singled out a new syndrome of crowding-terrorism (Engl. crowd) as a mass variant of sadistic aggression and vandalism. In development of pandemias of terrorism, there has been explained isolation of three donosological fractals: predisposition - mobbingogenic family; latent - bullyingogenic dispositions; initial - mass crowding; and three nosological ones: onset - social epidemy of terrorism; chronization - destructive social epidemy of terrorism; outcome - pandemia of terrorism and terminal complications.
ASSESSMENT OF VEGETATIVE STATUS OF OIL-AND-GAS INDUSTRY WORKERS FROM PERSPECTIVE OF CHAOS AND SELF-ORGANIZATION THEORY
Authors: Filatova O E , Provorova O V , Volokhova M A
Published: June 2022

To assess the vegetative status of oil-and-gas industry workers under impact of production factors, we have conducted a comparative transverse screening of human functional systems. The data obtained have been processed both with use of the mathematical statistics methods and the chaos and self-organization theory method. It has been established that the oil-and-gas industry workers had a bigger quasi-attractors’ volume and its increased skewness ratio of the body state vector in production conditions than engineers and research workers. Moreover, we have determined the most significant order parameter of the body state vector of the oil-and-gas industry workers in the North of the country - the Khanty-Mansi Autonomous Area - Ugra.
PREVALENCE OF UROLITHIASIS IN CHILDREN OF PRIMORSKY KRAI TOWNS WITH DIFFERENT ANTHROPO-MAN-INDUCED LOAD
Authors: Semeshina O V , Luchaninova V N , Kovalchuk V K , Melnikova E A
Published: June 2022

Influence of anthropo-man-induced load on Dysmetabolic Nephropathy (DMN) and Urolithiasis (U) prevalence in children of the Primorsky Krai has been studied. The study design included a sanitary, epidemiological and clinical stages. 513 children aged 3-14 years, born and residing in three towns of the Primorsky Krai with different degrees of anthropo-man-induced load stress have been examined (in Vladivostok, Dalnegorsk and Partizansk). The highest anthropo-man-induced water and air pollution load level was observed in Vladivostok. In the City of Dalnegorsk, water and air were less polluted, but the level of soil contamination (4.0 versus 1.0 and 2.0 in Vladivostok and Partizansk) was the highest one. DMN and U occurred significantly more frequently in Dalnegorsk than in Vladivostok and Partizansk (p < 0.001). It has been proved that in the Primorsky Krai, the anthropo-man-induced factor was not a priority risk factor for DMN and U development. Use of the noninvasive and easily managed system "Litos-test" allowed to reliably detect these diseases in the examined children.
SPECIES COMPOSITION OF PARASITES AND DEGREE OF THEIR PREVALENCE IN NENETS AUTONOMOUS AREA
Authors: Bobyreva N S , Shchipina L S , Degteva G N
Published: June 2022

Importance of parasitic diseases for public health appears from their diverse and profound effects on human bodies. Being a common human disease and frequent pathology, parasitoses burden course of many somatic and infectious diseases and cause reduction of labor activity and long-term disability. In the article, there have been presented the most common parasitoses in the Nenets Autonomous Area among Nenets patients and persons of other ethnic origin living in the Area, the City of Naryan-Mar and settlement Iskateli.
STUDY OF HUMAN HEALTH UNDER BIG INDUSTRIAL PLANT EXPOSURE USING HEALTH RISK ASSESSMENT AND EPIDEMIOLOGICAL STUDY METHODS
Authors: Zaitseva N V , Shlyapnikov D M , Shur P Z , Alekseev V B , Unguryanu T N , Buzinov R V
Published: June 2022

Hygienic studies conducted to establish and evaluate harmful effects of environmental factors in the affected area of the Solombalsky Pulp and Paper Mill (the Northern District of Arkhangelsk) on health of the Arkhangelsk population have detected specific chemicals that could cause changes in human health. In assessment of the risk of harmful effects due to chronic exposure to chemicals, there have been considered two types of effects: carcinogenic and non-carcinogenic. The main component in determination of carcinogenic risk for the population is chromium (VI). The largest contribution to the index of risk of respiratory diseases in acute exposure was introduced by sodium sulfate (to 47 %), of systemic disorders — power plants’ oil ash (up to 35 %). The resulting indices of risk of chronic inhalation exposure did not exceed the allowable values. According to the results of the epidemiological analysis of the morbidity level among the pediatric population of the Northern District of Arkhangelsk, the risk of diseases of the nervous system was 3.74 times higher, of digestive diseases - 1.31 times higher and the endocrine system - 2.35 times higher than in the group of the children living in relatively safe areas (the urban district Varavino - Factoria).
METABOLIC SYNDROME RISK FACTORS AMONG OIL PRODUCTION ENTERPRISE EMPLOYEES
Authors: Baidina A S , Nosov A E , Alekseev V B
Published: June 2022

In order to detect the metabolic syndrome risk factors in employees of an oil production enterprise causing development of the coronary heart disease, cerebrovascular disease, Diabetes type 2 and increased risk of developing cardiovascular complications, there has been undertaken a comparative cross-sectional screening study. All the workers (n = 200) were examined by a cardiologist, body mass index, blood pressure, blood lipids and blood aromatics were assessed. There has been established significant incidence of arterial hypertension (31.4 %), dyslipidemia (61.0 %) and overweight (68.0 %) in the employees working in conditions of exposure to aromatic hydrocarbons. There have been defined relationships of aromatic hydrocarbons with dyslipidemia (р < 0.05). The results of the cardiovascular risk assessment have shown, that it was necessary to consider impact of aromatic hydrocarbons on development of the metabolic syndrome in the workers as a predictor of cardiovascular pathology.
ANNUAL DYNAMICS OF CLIMATIC FACTORS AND POPULATION HEALTH IN KHANTY-MANSIYSK AUTONOMOUS AREA
Authors: Rusak S N , Eskov V V , Molyagov D I , Filatova O E
Published: June 2022

There has been presented an assessment of dynamics of environmental weather factors in the phase space of states in the framework of stochastic regularities and the theory of chaos using the author's programs and its correlation with indices of patients’ primary appealability concerning climate-sensitive diseases through the example of the City of Surgut. It has been found that the indices of the population appeals for climate-sensitive diseases had a close positive relationship with the value of the volumes of behavioral quasi-attractors of the meteorological parameters in the annual dynamics.
MIGRATION OF 232Th and 226Ra IN SOILS OF ARKHANGELSK CITY: BASIC REGULARITIES
Authors: Kryauchyunas V V , Shakhova E V
Published: June 2022

The basic regularities of spatial migration of natural radionuclides 232Th and 262Ra in the soils of the Arkhangelsk city have been established. The main factors affecting spatial distribution of the natural radionuclides included a type of housing, a geological and geomorphological structure of the territory and a water regime of the soils.
HEART RATE VARIABILITY STRUCTURE FEATURES IN PERSONS BORN IN MAGADAN REGION DEPENDING ON VEGETATIVE REGULATION TYPE
Authors: Maximov A L , Loskutova A N
Published: June 2022

390 senior schoolboys born in the Magadan region in the 1st-3rd generation aged 15-16 y. o. have been examined at rest to study 16 parameters of their heart rate variability. Based on the values of the index of tension (the stress index SI), the variation swing (MxDMn) and the spectrum total power (TP), the examined subjects were divided into three groups with prevalence of vagal, sympathetic or normotonic reactions of their vegetative nervous system. It has been found that the ranges of variability of the heart rate mathematical indices differed significantly depending on activity of the sympathetic or parasympathetic components of the nervous system, what conditioned methodically compulsory differentiation of the examinees according to the types of their vegetative regulation.
IMPACT OF CLIMATE FEATURES ON TYVA NATIVES METABOLISM
Authors: Krasilnikova V A , Hasnulin V I
Published: June 2022

This article presents results of a research of biochemical indicators of peripheral blood of the Tyva State University students (Tyva people). There have been considered metabolical features of the Tyva people depending on climatic conditions.
ECOLOGO-HYGIENIC PRECONDITIONS AND ENGINEERING APPROACHES TO MEDICAL WASTE MANAGEMENT
Authors: Shcherbo A P , Mironenko O V , Sushchy K K , Kozyrin K I , Soprun L A
Published: June 2022

In the article based on authentic investigation and research, the problem of medical waste management, its social, ecologo-hygienic and epidemiological urgency have been described. The dynamics of establishment and content of the national sanitary guidelines and regulations of 1999 and 2010 (co-authors of the current article participated in development of several of them) has been followed up; based on international sources, there have been considered critical comments of experts to these documents; in order to be understood clearly, some of the guidelines provisions’ versions have been updated.
CONDITIONING OF PHOTOINDUCED BACTERICIDAL ACTIVITY ON SURFACE OF TITANIUM DIOXIDE FILMS
Authors: Pleskova S N , Golubeva I S , Verevkin Yu K
Published: June 2022

Special surfaces based on titanium dioxide are developed for prevention of nosocomial infections. The reactive oxygen species (ROS) have been generated by the surfaces after their UV-irradiation. ROS caused destruction of bacteria. However, effectiveness of bactericidal activity of ТiO 2-films depends on several factors. Influence of time of UV irradiation, thermal (annealing) and chemical (benzene) treatment of films on the bactericidal activity, as well as the bactericidal effect against suspended and lyophilized bacteria have been studied. Three clinical isolates Staphylococcus aureus 956, Staphylococcus epidermidis 1061, Escherichia coli 321-5 have been used. Viability of the suspended bacteria has been determined with use of the classical method of counting CFU, viability of lyophilized bacteria has been determined with use of the method of estimation of coefficients of bactericidal extinction of control and test samples. It has been shown that the bactericidal effect of thin films against all strains increased with an increase in the flow of UV exposure. dermal and chemical treatment caused bactericidal activity recovery which was lost during the initial incubation of the bacterial suspension on the surface. Absence of fluid in the system increased the bactericidal activity of TiO 2-films.
PSYCHICAL AND VEGETATIVE DISORDERS OF COMPOUND TECHNICAL SYSTEM OPERATORS AS A RESULT OF PROFESSIONAL ACTIVITY
Authors: Ilina A V , Babaytsev S A , Bloschinskiy I A , Bogdanov N N , Makarov A K
Published: June 2022

One of the main objectives of maritime medicine is to reduce morbidity among operators of compound technical systems. It is known that chronic stress is one of the reasons of somatic disease development in this category of persons. In the article, the autonomic, mental, and emotional status of deep-sea facilities operators with different duration of professional activity have been integrally assessed. According to the results of the analysis of these indicators, there have been detected peculiarities of psycho-vegetative status depending on duration of exposure to stress factors; and have been identified the “target organs” for development of pathology in the operators with different experience.
FACTORS PROMOTING INCLUSION OF YOUNG PEOPLE IN USE OF PSYCHOACTIVE SUBSTANCES
Authors: Dyachkova M G , Mordovsky E A , Soloviev A G
Published: June 2022

Analysis of a relationship between substance use and other forms of addictive behavior of adolescents and young people of the Arkhangelsk region has been presented. Influence of intrafamily relationships and quality of parental control on likelihood of substance use by respondents has been studied. The necessity of multi-disciplinary programs for enhancement of self-preservation behavior of adolescents and young adults taking into account age, gender and living conditions has been proved.
PSYCHOLOGICAL WELL-BEING OF POPULATION OF MONOPROFILE TOWN OF EUROPEAN NORTH
Authors: Kashkina L Vladimirovna
Published: June 2022

The article presents results of a psychological study of the population of the monoprofile town of Novodvinsk which, as any monoprofile towns, is a special socio-territorial community. The specificity of this type of settlement gives an opportunity to study psychological well-being in renditions of certain territorial, political, economic and cultural isolation, what, firstly, provides priority of «local» problems in the minds of people; secondly, increases significance of such a factor as psychological well-being of population in monoprofile towns. Most studies of monoprofile towns are connected with research of socio-economic and environmental aspects. But it is also worthwhile noting that problems of psychological well-being, subjective well-being, socio-psychological adaptation and socio-cultural self-determination within the framework of social relations in monoprofile towns have not been studied enough.
DEPENDENCE OF EMOTIONAL STRESS RESISTANCE IN THE NORTH ASSOCIATED WITH IMPRINTED TYPE OF ADAPTIVE RESPONSE
Authors: Hasnulin V I , Hasnulina A V
Published: June 2022

It has been shown that an important factor in the formation of high adaptive resistance of newly arrived inhabitants of the North to psycho-emotional stress, which characterizes the level of climatic and geographic stress in the polar regions, is the mechanism of helio-geophysical imprinting of human adaptive response to action of biologically significant weather and geophysical disturbances. The helio-geophysical type of adaptive response provides higher adaptive reserves of the human body and determines its suitability for living and working in the regions with extreme climatic and geophysical conditions.
STUDY OF WORKING CONDITIONS OF OCCUPATIONAL UPPER EXTREMITY MYOFIBROSIS PATIENTS
Authors: Mal’kova N Yu , Popov A V
Published: June 2022

In 1982-2001 physical load-related diseases contributed 49.4 % to occupational morbidity in Saint-Petersburg. In the study of 553 blue-collar worker jobs, 56.1 % were found to be connected with physical overloads. It makes the problem of health protection of workers occupationally exposed to unfavorable effects, including muscle strain and overstrain, particularly topical. The object of the study was the working conditions assessment in heavy physical load jobs. Working conditions of plasterers, sinkers, mechanical assemblers, assemblers of metal vessel hulls were studied. Working process severity was shown to be the major common factor for all those jobs.
HOLISTIC APPROACH IN SYSTEM OF GENERAL KNOWLEDGE
Authors: Ushakov I B , Sorokin O G
Published: June 2022

New realias into which the mankind ran in the twenty first century are characterized by a tremendous upgrowth of science, techniques, information technologies and are accompanied by economical and social perturbations. They demand brand new views of the environment, the man and the society. In the article, the necessity to use a holistic approach in the system of general knowledge, especially in biology and medicine, has been grounded.
HEART RATE VARIABILITY OF THE YOUTHS WITH DIFFERENT TYPES OF HEMODYNAMICS
Authors: Pushkina V N , Varentsova I A
Published: June 2022

The research of the heart rate variability of the youths with different types of the heart rate regulation showed that persons with the hypokinetic circulation type under the heart activity apparent economization had the strictest structural organization of the cardiovascular system, what could adversely affect the velocity of its responses under stressors’ influence. The cardiovascular system of the youths with the hyperkinetic circulation type had high abilities to adapt urgently in cases of raised power inputs for the heart rate regulation. The youths with the eukinetic circulation type had an optimal structural organization of the heart functioning with the high level of its lability and adaptive reserves.
ATMOSPHERIC SUSPENSIONS AND HUMAN ECOLOGY
Authors: Golokhvast K S , Kiku P F , Khristoforova N K
Published: June 2022

The present review is devoted to the analysis of recent data on the study of atmospheric suspensions and their role in human ecology. Hygienic aspects of qualitative and quantitative composition of suspensions are discussed. Materials from articles in database Scopus were used (www.scopus. com), Web of knowledge (http://ip-science.thomsonreuters. com), Biological Abstracts (http://ip-science.thomsonreuters. com/cgi-bin/jrnlst/jloptions.cgi?PC=BA), PubMed (http:// www.ncbi.nlm.nih.gov/pubmed/).
VIOLATIONS OF HUMAN PROTEIN PROFILE IN HEAVY METALS EXPOSURE
Authors: Zemlyanova M A , Tarantin A V
Published: June 2022

The review considers influence of exposure of the most common heavy metals (lead, chromium, cadmium, manganese, nickel, vanadium) polluting the environment and being a risk factor of various health disorders progress, including metabolic changes in the protein profile of the human body.
MODERN APPROACHES TO ASSESSMENT OF METABOLISM DISORDERS OF XENOBIOTICS DURING THEIR ADMINISTRATION INTO BODY FROM EXTERNAL ENVIRONMENT
Authors: Zemlyanova Marina Aleksandrovna , Kol'dibekova Yu V , Zemlyanova M A , Koldibekova Yu V
Published: June 2022

In this review, there have been considered current approaches to identification and use of indicators that reflected xenobiotics metabolism disorders caused by, on the one hand, by genetically determined biochemical individuality and increased sensitivity of human body, on the other hand - by accumulation of them in body biological fluids during constant administration from external environment. The study of the basic components of enzyme systems that implement metabolism of xenobiotics, can detect abnormalities in the process of detoxification of chemicals, which makes it possible to adjust the main elements of the metabolic transformation of toxicants, and enzymatic detoxification system components considered as markers of metabolism of xenobiotics, due to increased individual sensitivity and stable flow of xenobiotics into the body from the environment.
POLYPOUS RHINOSINUSITIS
Authors: Vereshchagin Mikhail Yur'evich , Minkin A U , Vereshchagin M Yu , Minkin А U
Published: June 2022

In modern literature, there is observed morbidity growth of malignant tumors of the nasal cavity and the paranasal sinuses. Absolute majority of patients with this pathology start treatment already having III-IV stage of the disease. There is no tendency of a decreased neglect rate of malignant tumors of the nasal cavity and the paranasal sinuses. Treatment efficiency of patients with tumors of the nasal cavity and the paranasal sinuses depends on timely diagnostics. The main reason of late diagnostics is insufficient oncologic alarm in primary health care. All said above is actual, because the problems of therapeutic approaches to treatment of premalignant states havent been solved. At the same time, background processes preceding tumors of the nasal cavity and the paranasal sinuses are morphologically revealed in 56.7 % of patients. One of the most frequent background processes of malignant tumors development is chronic polypous rhinosinusitis. Prevalence of chronic polypous rhinosinusitis is high. There is observed an increase of the chronic polypous rhinosinusitis incidence
2-4 % annually in the last ten years. Higher frequency of inflammatory diseases of the nasal cavity and the paranasal sinuses is a result of serious ecological changes. There are only isolated literary data considering the chronic polypous rhinosinusitis as a premalignant state.
OCCUPATIONAL PATHOLOGY OF WORKERS EMPLOYED IN DIFFERENT PRODUCTIONS OF COPPER-NICKEL INDUSTRY IN FAR NORTH
Authors: Syurin S A , Gushchin I V , Nikanov A N
Published: June 2022

The study dealt with the data on 1 097 cases of occupational diseases that were first identified in 702 employees of the copper-nickel industry in Murmansk region in the period from 1970 to 2010. It has been established that in the structure of occupational diseases of workers engaged in all kinds of nickel and copper production, chronic bronchopulmonary diseases dominated. It was important that the nosological spectrum of respiratory pathology was largely determined by the nature of production. In contrast, the pathology of the musculoskeletal and nervous systems including the vibration disease occupied the leading segment in the structure of the occupational pathology of the copper-nickel ores miners. It has been concluded that in order to reduce the risk of occupational disabilities, it was necessary to decrease the degree of exposure to nickel aerosols (in nickel and copper metallurgical workers) and harmful physical factors (in copper and nickel ore miners).
ACUTE OCCUPATIONAL INTOXICATIONS BY CHLORINE AND AMMONIA: CLINICAL PICTURE, DIAGNOSTICS AND TREATMENT. CURRENT CONCEPTIONS
Authors: Akimov A G , Khalimov Yu Sh , Shilov V V
Published: June 2022

Current issues of industrial accidents resulting in chlorine and ammonia emissions have been considered in the article. In general, chlorine damage pathogenesis is related to the effect of acids generated in the process of its interaction with water, the effect of active oxygen forms, resulting in respiratory tract damage, surfactant damage and oxidative stress. Ammonia intoxication consequences are mainly caused by the local effect of ammonium hydroxide generated during interaction between ammonia and water on the airways’ and ocular mucosa. High ammonia concentrations result in NMDA receptor activation and ATP amount depletion. Pulmonary toxicant damage treatment covers reduction of the airways’ and ocular mucosa irritation phenomena, use of β-adrenergic receptor agonists; oxygen, corticosteroid and symptomatic medication by indications. Stage-by-stage treatment of the damage has been discussed.
ASSESSMENT OF PROPERTIES OF BILBERRY-BUSH GROWING AROUND KOLA NUCLEAR POWER PLANT
Authors: Kizeev A N , Ushamova S F , Zhirov V K , Ivkova N V
Published: June 2022

During 2009-2010 in the 15-km area around the Kola Nuclear Power Plant, there were studied bilberry-bush geo-botanical, morphological and physiological characteristics. In conditions of an insignificant (within the natural values) increase of background X-radiation, there have been revealed at least three types of adaptive mechanisms directed to decrease of radionuclides absorption by plant tissues thorough activation or inhibition of growth and development processes. The data obtained are under discussion concerning non-specific stress mechanisms.
TERMAL IMAGING ASSESSMENT OF ISCHEMIC HEART DISEASE
Authors: Popova N V , Popov V А , Gudkov А B
Published: June 2022

According to the literary sources, the thermal imaging role was assessed along with the general clinical examination methods for early diagnostics and adequate choice of medicinal therapy in patients with ischemic heart disease.
PHYSICAL DEVELOPMENT AND PHYSICAL FITNESS OF STUDENTS IN CITY WITH BAD ECOLOGICAL CHARACTERISTICS
Authors: Artemenkov A A
Published: June 2022

Cherepovets State University, Cherepovets, Russia In the article, physical development and physical fitness of students in the large industrial city of Cherepovets, the North-West region, with bad ecological characteristics have been studied. There have been obtained data on dynamics of weight and height characteristics of young men and girls aged 18-21 y. o., there have been worked out standards of the students’ physical development. It has been found that their height and body mass were changing with age generally in alignment. Deviations in physical development did not exceed 7.0 %. The level of physical fitness of the girls at the age of 18-20 y. o. was lower than the average level, and the young men’s physical fitness was at the average level. After the attainment of the age of 21 y. o., the young men and girls showed the observable lower level of physical fitness. The best results in physical development of both genders were detected mainly in the spring time. According to the Rufe test, the young men at the age of 18 y. о. showed the average and high working ability, and the young men aged 21, showed the average working ability. The girls’ working ability was estimated as good one.
APPLICATION OF ATC/DDD-SYSTEM FOR CORRECTION AND CONTROL OF ANTIBIOTICS USE IN TREATMENT OF PROSTHETIC JOINTS INFECTION
Authors: Bozhkova S A , Razorenov V L , Borisov A M
Published: June 2022

We have studied antibiotics use for treatment of prosthetic joints infection before and after implementation of the recommendations for antibiotic therapy. The recommendations are based on an analysis of the structure and drug resistance of 938 strains isolated from 618 patients with periprosthetic infection who were treated at the Department of Purulent Surgery from 2007 till 2009. The Department’s complete antibiotics use data in the period from 2007 till 2010 were processed according to the ATC/DDD system and expressed in defined daily doses (DDD) per 100 bed-days. In 2010 after introduction into practice of the recommendations, it has been shown that the total antibiotics use was reduced and the spectrum of antibiotics with antistaphylococcal activity was widened. Besides, the DDD-analysis of antibiotics use together with microbiological monitoring of the leading infection agents allows to make an expert examination of medicine use effectiveness and can be used for optimization and control of antibiotic therapy.
MALIGNANT TUMORS MORBIDITY AND ECOLOGICAL SITUATION IN SOME REGIONS OF REPUBLIC OF UZBEKISTAN
Authors: Abdihakimov A N , Niyazmetov B B , Madaminov A Yu , Daniyarova S S , Alidjanov H F
Published: June 2022

The purpose was to study features of distribution, dynamics of the usual and standardised indicators of oncological morbidity rate of the population of the Fergana Valley, to compare them with the data of the Republic Uzbekistan taking into account influence of climategeographical, industrial and nonindustrial factors of cancerogenesis. Initial material for the research was the data of the Uzbekistan State Statistical Committee and the organizational-methodical departments of the Andizhan, Namangan, Fergana and Tashkent regional oncological clinics from 1996 to 2007. In 1996, the standardised indicator of cancer morbidity of the male population of the Fergana Valley was 117.02 (female - 109.1). There is observed increased prevalence of a number of cancer nozological entities, in particular in the oil production regions - the mammary gland and esophagus cancer, in the cities with developed heavy engineering - the kidney and brain cancer.
HIV PREVENTION AND ITS ROLE IN CONTEXT OF HIV EPIDEMY PERSPECTIVE IN RUSSIAN FEDERATION
Authors: Smolskaya T T
Published: June 2022

The article presents an overview of the existing publications and the author’s several studies focusing on the need in strengthening HIV prevention in Russia. Based on the official data, the author attempted to provide an analysis of three stages of the Russian HIV epidemy (1987-2010) in terms of incidence levels, predominant transmission routes, involvement of various populations in the epidemy and prevention activities. The author describes social prevention projects implemented by AIDS Centres in 73 administrative territories across Russia in 2008-2009. There is a clear absence of unified approaches, with primary prevention focused on the general population and multiple projects targeting specific vulnerable groups such as IDUs, prisoners, migrants and SWs. The key partners in the projects were NGOs and international organizations. Most prevention projects were aimed at awareness-raising and information work. Long-term monitoring of prevention effect was problematic due to short lifespan of most projects. The vast experience of working with target groups is combined with the positive attitude to social surveys. Financial shortages are the key factor restricting prevention activities. The final section of the article contains discussion of highly active combined prevention which incorporates behavioural, structural and biomedical interventions as well as HAART. This approach, promoted as a standard by the international community, should be incorporated in the Russian concept of HIV prevention.
ECOLOGICAL-PHYSIOLOGICAL CHARACTERISTIC OF NORTHERN CLIMATIC FACTORS LITERATURE REVIEW
Authors: Gudkov А B , Popova О N , Lukmanova N B
Published: June 2022

Literary information on the ecological-physiological characteristic of the leading northern climatic factors has been analyzed. The combination of fluctuations of temperature and atmospheric pressure, high relative and low absolute humidity, strict wind regime, significant changes of solar activity, diversity of magnetic fields behavior, sharp photoperiodicity and pronounced UV-deficit cause a special structure of the northern regions’ climate. Per totality of climatic characteristics and taking into account the general biological effect of these factors, their combinations and the degree of manifestation, the territories of the North as a whole can be referred to the zone of uncomfortable natural-climatic living conditions with the elements of manifested extremeness of a number of parameters placing exclusive demands to human body functional systems.
FEATURES OF SLEEP-WAKE CYCLE IN PHYSIOLOGICAL AND ABNORMAL PREGNANCY
Authors: Gudz E B , Botasheva T L , Radysh I V , Avrutskaya V V
Published: June 2022

The article presents the characteristics of the daily cycle "wake-sleep" in women with physiological pregnancy and the risk of interruption. Significant differences in the sleep structure in normal and abnormal pregnancy have been established. It has been detected that changes in nocturnal sleep in abnormal pregnancies were characterized by reduced quantity and increased duration of the sleep cycles, multiple segmentation of sleep phases, lots of awakenings, and increased motor activity during sleep, increased number of apnea compared to normal pregnancy.
Experimental Analysis of the Piezomagnetic Properties of Ferromagnetic Steels Subjected To Cyclic Tensile Stress
Authors: Bao Sheng , Li Yan , Zhao Zhengye , Jiang Tao , Lou Huangjie
Published: June 2022

The objective of this research is to investigate the evolution of the piezomagnetic field of 30CrNiMo8 steel under cyclic tensile stress with variable amplitudes and asymmetrical cyclic tensile stress. The piezomagnetic field signal of an initially undemagnetised 30CrNiMo8 steel specimen
was recorded simultaneously during the whole loading process. It was found that the magnetic field variation is in contrast to the variation of the applied stress during the elastic stage. However, the magnetic field variation started to be consistent with the variation of the applied stress
when approaching and entering the plastic stage. A reasonable explanation was given for understanding this phenomenon. The Villari reversal point and the tail reversal point occurred during the plastic stage, which can be used to characterise the transition state from the elastic to plastic
stage. The variations of the Villari reversal point and the tail reversal point under cyclic tensile stress with variable amplitudes were slightly different from those under asymmetrical cyclic tensile stress.
In-situ Phase Analysis of Large Inclusions By Combining Computed Tomography And Energy-selective X-ray Diffraction
Authors: Cai Ji-Qing , Wang Huan , Wang Kun , Qin Ling , Zhang Peng-Cheng
Published: June 2022

The accurate positions of large inclusions in bulk metal can be determined using a computed tomography system but phase information for these inclusions cannot be obtained by the computed tomography method. In-situ phase information for internal material could be non-destructively obtained
by an energy-selective diffraction system; however, it is necessary to place the inclusion in the centre of the diffraction area to ensure that the obtained diffraction signal comes from the inclusion material rather than the base material, which is difficult without appropriate non-destructive
testing methods. In-situ phase information for large inclusions in the bulk metal could, in principle, be obtained by combining computed tomography and energy-selective X-ray diffraction (ESXRD) in one instrument. In this research, an X-ray analysis device with this capability is built. The
computed tomography system and the energy-selective diffraction system share the same tungsten target X-ray source, motion system and spatial coordinates. A simulated sample containing inclusions is fabricated with a diameter of 20 mm and a height of 20 mm. The base material of the simulated
sample is aluminium and the inclusions are α-Al2 O3 ceramic spheres with diameters of 1.5 mm, 2.5 mm, 3.5 mm and 5 mm. The diffraction information of some inclusions embedded in the simulated sample is successfully obtained using the combination instrument and the
factors affecting the diffraction signal of the inclusions are analysed.
Pengembangan Media Papan Catur Digital untuk Materi Bangun Ruang Kelas VI Sekolah Dasar
Authors: Hasbi Farhan Aditya , Roebyanto Goenawan , Ahdhianto Erif
Published: June 2022

Abstract: This research and development aims to produce digital chessboard media products for building materials that can help children learn about the characteristics and formulas of building spaces anywhere and anytime. This research and development model uses ADDIE (Analysis, Design, Development, Implementation, Evaluation) steps. The data collection instrument in this study was a validation questionnaire of material experts, media experts, and users. The results of research and development of digital chessboard media are said to be very feasible, practical and interesting.

Abstrak: Penelitian dan pengembangan ini bertujuan untuk menghasilkan produk media papan catur digital untuk materi bangun ruang yang dapat membantu anak belajar mengenai ciri-ciri dan rumus-rumus bangun ruang di mana saja dan kapan saja. Model penelitian dan pengembangan ini menggunakan langkah-langkah ADDIE (Analysis, Design, Development, Implementation, Evaluation). Instrumen pengumpulan data pada penelitian ini berupa angket validasi ahli materi, ahli media, dan pengguna. Hasil penelitian dan pengembangan media papan catur digital dikatakan sangat layak, praktis dan menarik.
Aging in Latin America and the Caribbean: Social protection and quality of life of older persons
Authors: Aranco Natalia , Bosch Mariano , Stampini Marco , Azuara Oliver , Goyeneche Laura , Ibarrarán Pablo , Oliveira Deborah , Retana Maria Reyes , Torres Ramirez Eric
Published: June 2022

In this report, we analyze older persons quality of life in Latin America and the Caribbean, its relationship with social protection policies, and how these policies must adapt to respond to population aging. We create a measure of quality of life of older persons which combines healthy life expectancy and income security. For the purposes of this report, we define older persons social protection as the combination of pensions, healthcare, and long-term care. These policies have a direct relationship with older persons quality of life. Pensions reduce old-age poverty. Healthcare improves older persons health status and reduces the risk of poverty due to catastrophic medical expenses. Long-term care improves the wellbeing of care dependent persons and their family caregivers. These positive impacts of older persons social protection are documented in a wide body of literature. For each type of policy, we assess the level of coverage, the quality of the benefits they provide, as well as their current and future sustainability, both from a fiscal and from a social perspective.
¿Hacia el neoperiodismo? La necesidad de adaptarse en el medio tecnológico
Authors: Ortiz Armas Gabriel , Orbe Tania
Published: June 2022

Cualquier persona que tiene acceso a las redes este rato puede difundir y dar información. Y se ha comparado lo que era cuando yo era joven, cuando yo empezaba la universidad. En este momento no hay unas fuentes que se pueda decir calificadas; tal vez nunca las hubo, pero por lo menos había la sensación de que había fuentes calificadas, de que había una especie de periodismo neutral, que informaba a todo el mundo. Este rato la información viene de todo lado.

Ya los medios tradicionales han perdido la hegemonía para hacer una información super descentralizada, y a la misma vez confusa. Creo que uno de los retos que tiene el periodismo ahora es cómo discernir lo que es fiable de lo que no es fiable, de cualquier locura que se ponga en las redes y a veces se puede volver noticia.

Vemos esto en la política, en la ciencia misma, vemos esto con la vacunación, con la elección de Donald Trump. En este momento estamos en un mundo confuso, y creo que un rol importante del periodismo moderno es orientar a la gente en toda esta increíble selva de información que existe. Los temas globales como el cambio climático, las pandemias, van a necesitar fuentes muy certeras para que no se generen noticias falsas porque son temas que nos pueden cambiar la vida de un día a otro.

Entonces, les felicito nuevamente. Gracias Tania y Eric. Estoy seguro de que van a ser unas conversaciones muy importantes. Sigan adelante con esto y ojalá siga siendo un esfuerzo recurrente para pensar, meditar y ver cuáles son las tendencias en el periodismo actual y en el futuro. Tienen todo el apoyo de la Universidad para seguir en estos eventos.