bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling and Forecasting of Tourist Arrivals in Crete Using Statistical Models and Models of Computational Intelligence
Authors: Goumas Stefanos K. , Kontakos Stavros , Mathheaki Aikaterini G. , Xristoforidis Sofoklis
Published: December 2020

In the past few decades, tourism has clearly become one of the most prominent economic trends for many countries. For many destinations, this trend will continue to rise, and tourism will become the most dynamic and fastest growing sector of the economy. Thus, the reliable and accurate forecasting of tourism demand is necessary in making decisions for effective and efficient planning of tourism policy. The objective of this paper is the modeling and forecasting the international tourist arrivals to four prefectures of Crete in the year 2012, based on the actual tourist arrivals data over the period 1993 – 2011, using one-step-ahead forecast. In particular, this paper presented a comparative study of time series forecasts of international travel demand for the four prefectures of Crete using a variety of statistical quantitative forecasting models along with neural networks and fuzzy models.
The Functional Building Blocks of Emoji in Consumer Engagement
Authors: Ge Jing
Published: December 2020

Firms are struggling with developing effective consumer engagement strategies on social media. Emoji have been identified as a potent tool for consumer engagement. Yet, their use in this context is not well understood. Treating emoji as digitally mediated visual signs, this study provides a framework of five functional building blocks of emoji in the consumer engagement domain (i.e., beatification, affection, information, participation, conversation), and offers emoji strategy recommendations (i.e., branding aesthetics, brand humanization, social listening, online community engagement). The proposed framework can advance visual semiotics theory by applying it in the context of social media, and also broaden emoji and consumer engagement literatures by providing conceptual support that addresses the symbolic significance of emoji in the complex and dynamic digital space. Utilised individually and together, these building blocks allow marketers to understand emoji as a new form of marketing semiotics, while also guiding them to enable and shape consumer engagement on social media.
Economic Impact of Information Industry Development and Investment Strategy for Information Industry
Authors: Lin Boqiang , Jia Zhijie , Song Malin
Published: December 2020

The information industry leads the digital revolution and innovation. With regards to what economic impact the development of the industry will bring about, there has been minimal focus from literature. This paper fills the knowledge gap by using a dynamic computable general equilibrium model. The results show the development will rapidly promote economic development and social welfare, promote the reduction of commodity prices and the rise of output by providing higher social productivity. Finance, public service, and some traditional industry (such as electricity) will benefit more when the information industry develops rapidly. At present, the industry development of the information industry is more directed at the service industry and final consumption. This paper implies the information industry can strengthen R&D investment towards supporting finance, public services and traditional industries, such as industrial control embedded software products, cloud computing technology, and emergency communication for traditional industries to increase the income.
The Influence of Organizational Ambidexterity on SME Speed of Internationalization
Authors: Silva Carina , González-Loureiro Miguel , Braga Vitor L.
Published: December 2020

Small and medium enterprises (SMEs) require a combination of organizational and individual skills to grow more rapidly in international markets. The question is whether there is an ideal combination to compete in the present (exploitation orientation) or to prepare to compete in the future (exploration orientation), and whether managerial cognition plays a role on determining international growth. The analysis of Portuguese manufacturing SMEs suggests that the manager's cognitive systems do not have an overall influence on the growth of foreign sales to total sales (FSTS), but the two cognitive systems (experiential and analytic) have a different influence on international exploitation and exploration. International exploration and exploitation mediate the relationship between the latter variables. This study contributes to a better understanding of the role that organizational ambidexterity plays on the SMEs' speed of internationalization and how the manager's cognitive systems influence this organizational orientation.
Technology Used in Knowledge Management by Global Professional Event Services
Authors: Borodako Krzysztof , Berbeka Jadwiga , Rudnicki Michał
Published: December 2020

Professional service providers, due to their use of information and communication technology (ICT), could be global players. The market for congresses, conferences, trade shows, and business events attract clients and contractors from around the world. Competition between firms motivates them to apply advance technologies that enable faster and easier cooperation. The aim of this exploratory study was to identify and classify ICT used in knowledge management among professional event service providers. By applying method triangulation (interviews, meta-linguistic coding, analysis of association graphs, and netnography), the authors identified key terms related to knowledge management and technology. Firms differed by type and length of market presence. The technologies used by firms were grouped into five types. The analysis of competition in search engines confirm high scores for technology service providers (i.e., cloud data and beacon).
Numerical Study of a Williamson Fluid Past a Semi-Infinite Vertical Plate with Convective Heating and Radiation Effects
Authors: Amanulla Ch. , Wakif Abderrahim , Saleem S.
Published: December 2020

In the present paper, we investigated mathematical model of the magnetohydrodynamic flow and heat transfer in an electro-conductive polymer on the externalsurface of a semi-infinite vertical plate under radial magnetic field. Thermal radiation andconvective heating effects are considered at the semi-infinite plate surface with modifiedboundary conditions. The Williamson viscoelastic model is employed which isrepresentative of certain industrial polymers. The non-dimensional, transformedboundary layer equations for momentum and energy are solved with the second orderaccurate implicit Keller box finite difference method under appropriate boundaryconditions. Validation of the numerical solutions is achieved via benchmarking withearlier published results. The influence of Williamson viscoelastic fluid parameter,magnetic body force parameter, convective heating, radiation parameter, stream wisevariable and Prandtl number on thermos-fluid characteristics are studied graphically. Themodel is relevant to the simulation of magnetic polymer materials processing.
Sex-Biased Aging Effects on Ig Somatic Hypermutation Targeting
Authors: Cui Ang , Chawla Daniel G , Kleinstein Steven H
Published: December 2020

Aged individuals, particularly males, display an impaired level of Ab response compared with their younger counterparts, yet the molecular mechanisms responsible for the discrepancy are not well understood. We hypothesize that some of this difference may be linked to B cell somatic hypermutation (SHM) targeting, including error-prone DNA repair activities that are crucial to Ab diversification. To examine the effects of aging on SHM targeting, we analyzed B cell Ig repertoire sequences from 27 healthy male and female human subjects aged 20–89. By studying mutation patterns based on 985,069 mutations obtained from 123,415 sequences, we found that the SHM mutability hierarchies on microsequence motifs (i.e., SHM hot/cold spots) are mostly consistent between different age and sex groups. However, we observed a lower frequency in mutations involving Phase II SHM DNA repair activities in older males, but not in females. We also observed, from a separate study, a decreased expression level of DNA mismatch repair genes involved in SHM in older individuals compared with younger individuals, with larger fold changes in males than in females. Finally, we showed that the balance between Phase I versus Phase II SHM activities impacts the resulting Ig phenotypes. Our results showed that the SHM process is altered in some older individuals, providing insights into observed clinical differences in immunologic responses between different age and sex groups.
The Euler characteristic of Out($F_n$)
Authors: Borinsky Michael , Vogtmann Karen
Published: December 2020

We prove that the rational Euler characteristic of Out(

F_n

) is always negative and its asymptotic growth rate is

\Gamma (n-\frac{3}{2})/\sqrt{2\pi}\log^2n

. This settles a 1987 conjecture of J. Smillie and the second author. We establish connections with the Lambert

W

-function and the zeta function.
SLIKA OBITELJI U KNJIŽEVNOJ TRILOGIJI ZLATNI DANCI JAGODE TRUHELKE
Authors: Verdonik Maja , Kovač Josipa
Published: December 2020

With an insight into the theoretical determinants of the children’s novel and the theme of the family in the Croatian children’s novel, the paper presents the importance and role of the family in the literary trilogy Golden Days (Zlatni danci), written by one of the founders of Croatian children’s realistic prose, Jagoda Truhelka. The aim of the paper is through analysis of the available scientific sources and literary texts to present the literary motifs present in describing the image of the family in the literary trilogy Golden Days (Zlatni danci). Jagoda Truhelka introduces readers to her idyllic childhood, which is characterized by family harmony, the Christian spirit in raising children, patriotism and the interdependence of children and parents. These are the values on which, as constituent components, the analysis of the image of the family in Truhelka’s children’s novels, presented in the paper, is based. The literary trilogy Golden Days (Zlatni danci) depicts a tightly structured, homogeneous family in which the father-teacher played a major role. Religious principles were a guide in the upbringing of children, based on Christian principles also present in the descriptions of religious holidays and customs. Nurturing patriotism is evident in everyday storytelling and children’s games, with the father once again being the one who played the most important role in it. Child and parental interdependence are present in the constant care of family members for each other, especially in moments of children getting into trouble in situations where parents were not present. Growing up in Jagoda Truhelka’s family was happy because it gave the children what every child deserves: love, attention, feelings of security, belonging, tenderness and respect. The image of such a family, presented in the literary trilogy Golden Days (Zlatni danci), certainly still contributes to the upbringing of today’s children.
MODELING AND OPTIMIZATION OF THE PROCESS OF GEAR MILLING OF CYLINDRICAL GEARS WITH WORM MILLING CUTTERS
Authors:   Belarusian National Technical University, KANE Mark M. , SHELEG Valeriy K. ,   Belarusian National Technical University, KRAVCHUK Marina A. ,   Belarusian National Technical University
Published: December 2020

The paper considers influence issues of modes of milling cylindrical gears by hobbing cutters on the parameters of surface quality of the treated teeth, selection of milling mode, relevance of the performed research, possibility of using its results for the design of technological processes of manufacturing cylindrical gears, quality control of teeth surfaces both when cutting teeth and in finished gears. The article gives a method, conditions and main results of experimental study of the influence of gear milling modes by a worm milling cutter (feed S, mm/min; cutting speed V, m/min) of cylindrical gears on the roughness parameter Ra, μm; microhardness Hμ, MPa; macroscopic and microscopic stresses of σ1 and σ2, MPa; of the tooth surfaces. It is shown in particular that the dependence of Ra on V and S with sufficient accuracy (the average relative error of the coupling equation εср is 5.2–26.5 %) can be described by a firstdegree polynomial, and the dependences of Hμ, σ1 and σ2 on V and S with sufficient accuracy (εср = 4.7–12.8 %) can be described by a second-degree polynomial. It was found that the feed S has a 2.5–14 times greater effect on the change in Ra, Hμ, σ1 and σ2 than the cutting speed V during gear milling of cylindrical gears. A method for optimizing the cutting modes S and V is proposed and described, taking into account their influence on the main parameters of the process of gear milling of cylindrical gears with worm milling cutters.
DEVELOPMENTS IN LAYOUT AND INCREASING OF TRANSVERSE STABILITY OF MINING DUMP TRUCKS OF EXTRA HIGH LOAD CAPACITY
Authors:   OJSC “BELAZ” — Management Company of Holding “BELAZ-HOLDING”, STEPUK Oleg G. , NASKOVETS Alexander M. ,   OJSC “BELAZ” — Management Company of Holding “BELAZ-HOLDING”, MOISEENKO Vladimir I. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, SIDORENKO Aleksandr G. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus
Published: December 2020

Main feature of modern mining dump trucks is the need to ensure the transportation of minerals with minimal costs, which is achieved by deepening the quarries (in order to save overburden), increasing the slopes of roads, reducing the distance of cargo transportation, increasing the load capacity of machines and improving the safety of their movement. It is shown that new work conditions of dump trucks and major specific requirements are resolved mainly at the stage of layout of machines by optimizing wheel arrangement of dump trucks, loading of tires and their performance, providing specific power of the propulsion system, choice of the transmission type and its units, and major systems to ensure operational safety: brakes, steering, stability of motion. Special attention is paid to the creation of a new system for improving lateral stability and its design for dump trucks with a load capacity of more than 400 t. The results of operational studies of the main layout and design solutions adopted for a dump truck with a load capacity of 450 t are presented. Efficiency of the decisions made is shown which made it possible to create a mining dump truck superior to all analogues in the world by indicators of the main operational properties that ensure competitiveness: fuel efficiency, performance, and operating costs. A system created for the first time for increasing lateral stability (schematic diagram and structural elements) confirmed the projected traffic safety in typical quarries and the necessary life in operation.
SYNTHESIS OF THE NANOCOMPOSITE BASED ON IMPACT DIAMONDS AND SILICON CARBIDE UNDER CONDITIONS OF HIGH PRESSURE AND TEMPERATURE
Authors:   Presidium of the NAS of Belarus, VITYAZ Petr A. , SENYUT Vladimir T. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, ZHORNIK Viktor I. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, VALKOVICH Igor V. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, KOVALIOVA Svetlana A. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, MOSUNOV Evgeniy I. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, AFANASYEV Valentin P. ,   V.S. Sobolev Institute of Geology and Mineralogy of the Siberian Branch of the RAS
Published: December 2020

The article studies the structure, phase composition and physicomechanical characteristics of the nanocomposite based on impact diamonds. It is shown that the additions of a binder based on SiC and Si lead to reduction of the defectiveness of the nanocomposite and increase in the uniformity of its structure compared to the material without additives. Moreover, increase in the binder content also leads to the inversion of the structure type of the nanocomposite from polycrystalline to matrix. It is established that the addition of amorphous carbon black and boron affects the refinement of the nanocomposite matrix structure due to the formation of secondary finedispersed nanostructured SiC and boron carbide. Preliminary mechanical activation of the reaction mixture leads to structural changes in the synthesized material in comparison with the material obtained without the use of mechanical activation. In this case, the hardness of the samples obtained under comparable synthesis modes increases, which is associated both with the formation of a fine-grained structure of the material and with the phase transformation of lonsdaleite to diamond. An analysis of the microhardness and heat resistance of the obtained samples makes it possible to conclude that the achieved level of physicomechanical parameters of the diamond nanocomposite allows it to be used in a stone-processing tool for treating medium hard rocks.
THERMODYNAMIC MODEL OF AERODYNAMIC SOUND HARDENING METHOD
Authors:   Baranovichi State University, JIGALOV Anatoliy N. , SHELEG Valeriy K. ,   Belarusian National State University, BOGDAN Dmitriy D. ,   Baranovichi State University
Published: December 2020

As a result of scientific research, a method of aerodynamic sound hardening (ADH) has been developed and patented, which makes it possible to achieve improved properties of hard alloys by reducing their defectiveness, improving the homogeneity of the structure. The physics of the ADH process is that the hardened product is preheated to an acceptable temperature at which the hard alloy does not lose the plasticity and hardness acquired during manufacture. Then the product is exposed to sound frequency waves, reduced in the range of 140...160 Hz into a resonant state, in which the formation of a resonant amplitude increased by several hundred times occurs. The article gives a description of the essence of the created ADH method. The dependence for determining the action energy on a hardened solid by ADH is provided. A thermodynamic model of the ADH method is presented, based on energy thermal and wave effects on the hardened structure. On the basis of the thermodynamic explanation, the ADH method is reduced to a change in the initial structure of the hard alloy under the influence of temperature and wave resonant energy fluxes on it, through which activating and dissipative processes of energy outflow are excited in the hardening object in the mode of an open thermodynamic system. In addition, the quasi-static process of wave energy transfer, carried out in a non-equilibrium medium, significantly exceeds the relaxation time of the strengthening system. When hardening by ADH, the impact toughness increases by 19–23 % in hard alloys, while the values of impact toughness equal to 39.54–42.05 kJ/m2 are achieved, the hardness according to the HRC parameter increases by 3.0–5.2 %.
SELECTION OF RATIONAL POLISHING MODES FOR CLADDED CHROME COATINGS
Authors:   Joint Institute of Mechanical Engineering of the NAS of Belarus, LEVANTSEVICH Mikhail A. , MAKSIMCHENKO Natalia N. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, PILIPCHUK Yahor V. ,   Belarusian National Technical University
Published: December 2020

As a result of experimental and statistical modeling, dependencies were obtained that establish the effect of polishing modes (the number of passes of the polishing wheel, the value of the wheel tightness) on the roughness and thickness of the chrome coating obtained by the method of deformation cladding with a flexible tool. It was found that within the selected intervals of variation of the factors, an increase in the tightness of the polishing wheel and the number of passes of the wheel leads to a decrease in both the parameter of the roughness Ra and the thickness of the coating, however, with different degrees of intensity. The number of passes of the polishing wheel has a decisive effect on the value of the surface roughness of the clad layer after polishing. The effect of polishing modes on the thickness of the cladded coating is more complex, since it is demonstrated both in the individual comparable influence of both factors and in their interaction. The optimal modes of polishing of hydraulic cylinder rods subjected to chromium plating by the method of deformation cladding with a flexible tool have been determined. After the experimental check in the conditions of JSC “Minsk Automated Lines Plant named after P.M. Masherov” (Republic of Belarus), the established technological modes of polishing were added to the technological process of chromium plating of rods. It confirms the effectiveness of using the calculated dependencies.
DEVELOPMENT OF CALCULATION METHOD FOR TENSILE STRENGTH OF ROCK SAMPLES UNDER COMPRESSION
Authors:   Institute of Geotechnical Mechanics named by N. Poljakov of National Academy of Sciences of Ukraine, VASIL’EV Leonid M. , ZHURAVKOV Michael A. ,   Belarussian State University, VASIL’EV Dmitriy L. ,   Institute of Geotechnical Mechanics named by N. Poljakov of National Academy of Sciences of Ukraine, MALICH Mykola G. ,   National Metallurgical Academy of Ukraine, NAZAROV Oleksandr E. ,   Institute of Geotechnical Mechanics named by N. Poljakov of National Academy of Sciences of Ukraine
Published: December 2020

The paper describes a procedure for improving the approach to determining the ultimate strength of rock samples, the basic method is L. Prandtl’s method. In earlier works of the authors of this paper, the L. Prandtl’s method was improved in relation to rocks, using a general algebraic equation for calculating horizontal normal stresses depending on the vertical component and mechanical characteristics of the rock. Here, the authors reject the assumption that the tangent contact stresses resulting from L. Prandtl's solution do not depend on the abscissa x and on the variable vertical stresses, in contrast to the well-known Coulomb–Amonton law, according to which the tangent stresses are directly proportional to the vertical pressure. The regularities of contact normal and tangential stresses distribution at failure of prismatic samples are clarified. As result, the method was developed for calculating the tensile strength of samples with three characteristic values of mechanical properties: kп, yield strength of material in shear; ρ, angle of internal friction; fс, coefficient of contact friction. These characteristics can be established experimentally by simple experimental studies. The proposed approach is effective for constructing ultimate curves and diagrams of “stress — longitudinal strain” of rocks in the case of contact friction. A comparative evaluation is given for the proposed method for calculating the tensile strength of samples during their destruction with experimental data. Comparison of the calculated tensile strength with experimental data shows that the relative error of calculations according to the proposed method is significantly lower than the relative error of calculations performed using the E. Unksov’s method. The proposed method can be recommended for practical application.
TANMANA BHOJANGATAH CHITAH (PSCHYE AND FOOD)
Authors: Sandeep Singh Tiwari  , Mamta Masram  , Prakhar Goyal
Published: December 2020

Three million ago of the south Asian region, India had his own traditional system of medicine which known as Ayurveda. It explains the Rasa, Guna, Virya, and Vipaka of the Dravyas (Medicinal as well as food materials). It gives us some unique concepts to take the food (Asta ahar vidhi Visheshayatana) and its effect on body and mind. Ayurveda is science of wellness which primarily deals in food and behavioural aspects. Food and psychology has a good relation in Ayurveda. Emotions and psychological state has a very profound role in the proper digestion and metabolism of food. Ayurveda explains different psychological and emotional state of digestion, and establishment of ground rule that we should have food with psychological relaxation without any mental disturbance. As well as impact of occupational stress and weight conscious diet on digestion according to modern medical science is discussed. Ayurveda already have many references in many places of different Samhitas especially in Charak, Sushrut and Astang. They clearly told that we have to follow the rules of Asht-Aharvidhi Visheshayatana and they coded that, food has his own properties which helps to enhance the physical factors as well as mental factors of the body. Balanced food habits complete the both Prayojana of the Ayurveda which is “Swasthasya Swastha Rakshanam and Aturasya Vikara Prashamanm Cha”. Emotional status of the person at the food taking time also plays an important role of its digestion and metabolism in the body. A big question arise here that whether first psychology effect in digestion of food or food affecting the psychology of the person.
Diagnostic value of lung ultrasound versus chest CT in COVID-19
Authors: Petrikov S. S. , Popova I. E. , Abuchina V. M. , Muslimov R. Sh. , Khamidova L. T. , Popugayev K. A. , Kokov, L. S.
Published: December 2020

Lung ultrasound demonstrates a high diagnostic value in the assessment of lung diseases.

Aim.To determine the diagnostic accuracy of lung ultrasound compared to chest computed tomography (CT) in the diagnosis of lung changes in COVID-19.

Materials and methods.The retrospective study included 45 patients (28 men) aged 37 to 90 years who underwent polypositional lung ultrasound with an assessment of 14 zones. The study compared lung echograms with chest CT data in assessing the prevalence of the process and the nature of structural changes. The diagnostic accuracy, sensitivity, and specificity of lung ultrasound in comparison with CT scans were determined, 95% confidence intervals (CI) were calculated.

Results.In 44 patients (98%), CT revealed pathological changes with subpleural localization in both lungs. Of these, in 30 cases, the inflammation was limited only to the subpleural parts, and in 14 cases, the changes spread to the basal parts of the lungs, while ultrasound revealed changes at the depth of the lesion no more than 4 cm. The lesion of 10–11 zones according to lung ultrasound corresponds to CT 1–2 degrees, the lesion of 13–14 zones — CT 3–4 degrees. The sensitivity of ultrasound to detect lung changes of various types was ≥ 92%. The highest sensitivity of 97.9% (95% CI: 92.8–99.8%) was determined for small consolidations on the background of interstitial changes (degree 1A+, 1B+), which corresponded to “crazy-paving” pattern on CT. The specificity depended on the nature of the changes and varied from 46.7 to 70.0%. Diagnostic accuracy was ≥ 81%, the maximum values of 90.6% (95% CI: 85.6–94.2%) were obtained for moderate interstitial changes (grade 1A) corresponding to ground-glass opacity (type one) according to CT data.

Conclusion.The sensitivity of ultrasound to detect lung changes in COVID-19 is more than 90%. Lung ultrasound has some limitations: inability to determine the prevalence of the process clearly and identify centrally located areas of changes in the lung tissue.
Features of the management of cancer patients during the COVID-19 pandemic
Authors: Sekacheva M. I. , Rusanov A. S. , Fatyanova A. S. , Boroda A. M. , Istranov A. L. , Rusanov S. N. , Babayeva Yu. V. , Poddubskaya E. V.
Published: December 2020

Novel coronavirus infection, causing COVID-19, is not fully controlled for today. In periodicals, there are often reports of a high risk of severe complications in cancer patients during the development of COVID-19. The review presents information from literary sources based on the experience gained in overcoming this formidable disease and its consequences using the examples of foreign colleagues of clinicians, as well as domestic experience and recommendations for the treatment of cancer during the pandemic COVID-19 of the National Medical Research Center for Radiology of the Ministry of Health of Russia with the participation and support of the Association of Oncologists of Russia and the Association of Health Organizers in Oncology. The information is based on actual data collected through the search of sources in abstract and sciencemetric electronic databases, open access resources in Russian and English. The review presents recommendations from international and domestic professional communities regarding the routing and multidisciplinary treatment of cancer patients during the pandemic period.
Legislative regulation improvement of health protection in the context of the COVID-19 epidemic
Authors: Morozov D. A. , Vtorushin D. V. , Polutsigan A. A. , Seleznev G. I.
Published: December 2020

The experience of the health protection legal regulation during the spread of a new coronavirus infection (SARS-CoV-2) is presented. The key areas that required a number of state decisions to ensure the sanitary and epidemiological well-being of the Russian Federation and the protection of citizens are outlined: assigning the Government of the Russian Federation and State authorities of the Russian Federation subjects the authority to regulate special health protection; introducing responsibility for non-compliance with the rules of conduct in an emergency or threat of its occurrence; providing citizens with medicines, medical devices and personal protective equipment; construction, re-profiling and financing of medical organizations; support for medical workers, implementation of incentive payments. The review is based on the analysis of normative legal acts adopted by legislative and Executive authorities at all levels, their interaction, as well as the work carried out by the State Duma, the State Duma Committee on health protection, and parliamentary control. The proposals of the State Duma Committee on health protection on further improvement of the legislation of the Russian Federation in the field of health protection are reflected.
Silent hypoxemia in a patient with severe SARS-CoV-2 pneumonia
Authors: Palman A. D. , Andreev D. A. , Suchkova S. A.
Published: December 2020

Patients with COVID-19 are typically characterized by severe lung injury with the development of acute respiratory failure. However, in some patients, subjective well-being may remain relatively satisfactory for a long time and, despite severe hypoxemia, they do not complain of shortness of breath.

Case report. We observed a 65-year-old man hospitalized with severe SARS-CoV-2 pneumonia, low level of blood oxygen saturation, but at the same time without complaints of shortness of breath. Only as the disease progressed with a decrease in oxygen saturation when breathing atmospheric air (SpO2 ) lower than 85% he began to notice a feeling of lack of air. The patient’s condition worsened and as a result, he died in the intensive care unit from multiple organ failure.

Discussion. This case clearly illustrates one more feature of the course of pneumonia associated with the novel SARSCoV-2 coronavirus and shows that SpO2 measurement is one of the leading objective criterion that allows a doctor to assess the real severity of a patient’s condition with COVID-19.
Isolated bitemporal hemianopia in a patient with COVID-19
Authors: Zharkova M. S. , Tikhonov I. N. , Efremova I. V. , Ondos S. A. , Nadinskaia M. Yu. , Ivashkin V. T.
Published: December 2020

Introduction. Symptoms of lesions of the I, VII and IX pairs of cranial nerves during SARS-CoV-2 infection are observed in about a third of cases. Isolated bitemporal hemianopia as a symptom of optic nerve damage at the chiasmal level in patients with COVID-19 has not been described yet.

Case report. A 65-year-old man with a history of arterial hypertension and myocardial infarction and confirmed COVID-19 infection with severe lung damage on computed tomography. Patient developed bitemporal hemianopia, confirmed by the Donders test, on the second day of hospitalization. CT scan revealed no lesions and organic pathology in the parachiasmatic region and in the substance of the brain. Two days later, there was a complete restoration of lateral vision.

Discussion. The most likely cause of bitemporal hemianopia was microthrombotic or inflammatory lesion at the chiasmal level. Risk factors for thrombotic complications: male gender, age 65, history of cardiovascular diseases, increased D-dimer levels, and signs of systemic inflammation (increased levels of C-reactive protein, fibrinogen, lactate dehydrogenase, and ferritin). An alternative hypothesis for the development of chiasmal syndrome may be direct viral invasion SARS-CoV-2 of the central nervous system.
Surgical Management of Necrotizing Sialometaplasia of Hard Palate: A Case Report
Authors:   Lecturer, MDS, Palanivel Indu
Published: December 2020

Necrotizing Sialometaplasia is rare and in the oral cavity it accounts <1% of all biopsied lesion. For decades Necrotizing Sialometaplasia were treated by conservative management as it is a self healing lesion. The progressive healing period was reported from 2 weeks to 3 months in the literature. Is necrotizing sialometaplasia a self-limiting disease? Here we report a case of non-healing necrotizing sialometaplasia which was treated by surgical management. Complete regression of the lesion was evident after the surgical management and no recurrence until two years of follow-up.
Factors Impact Reducing Money Earning Manipulation withintheListed Malaysian Companies; theModerating Role ofAccounting Ethics
Authors:   PhD. Research Scholar, Centre of Post Graduate Studies Limkokwing University of Creative Technology, Cyberjaya, Malaysia, SAREM YAMAN
Published: December 2020

This study aims to investigate the impact of three dimensions suggested by Beneish M-Score model on reducing money earning manipulation within listed companies in Malaysia. Also, examining the moderation role of accounting ethics toward the improvement of these factors on reducing money earning manipulation. These three dimensions called asset quality management, accrual quality management, and leverage quality management. This study follows the cross-section method. The questionnaire instrument is used to collect the data from 370 employees in financial and insurance business of Malaysia. The empirical analysis of structural model of the study revealed that the direct relationships of financial management transactions dimensions are significantly positively related to reducing money earning manipulation. The path analysis confirmed moderating effect of accounting ethics has also been found positively significant positive on the relationship between financial management transactions and reducing money earning manipulation. The present study is first of its kind to explore the moderating effect of accounting ethics among financial and insurance business of Malaysia. It suggested that financial management transactions are an important concept for management of financial and insurance organizations, which can considerably influence working environment and reduce money earning manipulation.
Estudio de la transversalidad de los contenidos en Educación Física a través de los currículos competenciales (Study of the transversality of the contents in Physical Education through the competency-based curricula)
Authors: Solà Santesmases Josep
Published: December 2020

El artículo tiene por objetivo analizar la evolución de los currículos competenciales a través del estudio de la transversalidad de los conocimientos mediante el análisis documental de las principales regulaciones jurídicas educativas. El análisis de contenido permitirá un enfoque transversal sincrónico para comparar las leyes y RD estatales con los decretos y normativas autonómicas catalanas, y un enfoque longitudinal diacrónico para comparar la evolución de los currículos competenciales desde su aparición en la LOE hasta su consolidación en la LOMCE. Dicho análisis de contenido se fundamentará en las regulaciones para la Educación Secundaria Obligatoria (ESO) a través de la materia específica Educación Física, contrastando las ejemplificaciones prácticas con la materia troncal de matemáticas.
Las conclusiones determinan el florecimiento de las competencias en los currículos y el asentamiento de la transversalidad como intervención necesaria para su logro. De una transversalidad centrada en los contenidos disciplinares como metodología competencial (conexiones con las otras materias) se evoluciona a la transversalidad basada en las competencias y en la transferibilidad de los conocimientos a contextos reales (tratamiento globalizado de los contenidos). 
Abstract. The article aims to analyse the evolution of competency-based curricula through the study of the transversality of knowledge of the main educational legal regulations. The content analysis will allow a synchronous transversal approach to compare the state laws with the decrees of the autonomous administration, and a diachronic longitudinal approach to compare the evolution of the competences curricula from its appearance in the LOE to its consolidation in the LOMCE. Physical Education, a specific subject, will support the exemplification, contrasting it with the core mathematics subject. The conclusions determine the flourishing of competencies in the curricula and the establishment of transversality as a methodological aspect necessary for its achievement. From a transversality focused on disciplinary contents as a competency methodology (connections with other subjects) it evolves to transversality based on competences and on the transferability of knowledge to real contexts (globalized treatment of content).
Efecto de la combinación metodológica de aula invertida e instrucción entre pares en las calificaciones académicas de estudiantes universitarios de Ciencias de la Actividad Física y del Deporte (Effect of the methodological combination based on flipped c
Authors: Falcón Miguel David , Sevil-Serrano Javier , Peñarrubia-Lozano Carlos , Abós-Catalán Ángel
Published: December 2020

El desarrollo de nuevos métodos de enseñanza-aprendizaje en la educación superior demandan la aportación de evidencias científicas que señalen su efectividad en el rendimiento académico del alumnado. El presente estudio evalúa el efecto de un programa de intervención basado en la combinación de las metodologías de aula invertida e instrucción entre pares sobre una parte de las calificaciones académicas obtenidas por estudiantes universitarios en una asignatura. Se realizó un diseño cuasi-experimental en el que participaron 52 estudiantes universitarios del 3º curso de Grado en Ciencias de la Actividad Física y el Deporte que cursaban la asignatura de Gestión y Organización de Eventos. El grupo experimental recibió durante tres clases los contenidos de la asignatura a través de la combinación metodológica de aula invertida y de instrucción entre pares, mientras que el grupo control lo hizo siguiendo una metodología tradicional. Para comparar la eficacia de la intervención se midió la calificación académica de un contenido de la asignatura a través de un examen teórico. Los resultados del estudio mostraron una asociación positiva y significativa entre recibir clases con la combinación metodológica y el acierto en el examen. Por tanto, la combinación de una metodología utilizada parece mostrarse más eficaz que la metodología tradicional para mejorar la compresión de conceptos teóricos en el alumnado universitario.
Abstract: The development of new teaching-learning methods in higher education require the contribution of scientific evidence that indicates whether these types of methodologies are effective. The aim of this study was to assess the effect of an intervention programme based on the combination of flipped classroom and peer instruction on the grades of university students in an academic subject. Fifty-two university students of the 3rd course of Physical Activity and Sports Sciences Degree participated in this quasi-experimental study. The contents of the subject were taught through three lessons by a methodological combination of flipped classroom and peer instruction in the experimental group, while in the control group the same contents and number of lessons were taught following a traditional methodology. The students' grades were measured in a part of the subject by means a theoretical exam to assess the effectiveness of the two types of methodologies implemented. The results of the study showed a positive and significant association between receiving lessons with the methodological combination and getting the different exam questions right. Therefore, the combination of this methodologies seems to be more effective than the traditional methodology for improving the understanding in university students.
Strain Longitudinal e Acidente Vascular Encefálico Isquêmico na Ausência de Cardiopatia Conhecida
Authors:   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Cordeiro de Morais Junior Jeova ,   Escola Baiana de Medicina e Saúde Pública, Salvador, Bahia, Brasil, Pertile Salvioni Nayane Carolina ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Roosevelt de Vasconcelos Lima Dannyl ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Firmino Confessor Crissvânia ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Costa Galdino Junior Alexsandro Paulo ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Sodré Cardoso Lara ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, da Silva Antônio Marconi Leandro ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Lima Joao ,   Johns Hopkins Hospital, Baltimore, MD, EUA, da Costa Armstrong Anderson ,   Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil, Lemos Correia Luis Claudio ,   Escola Baiana de Medicina e Saúde Pública, Salvador, Bahia, Brasil,   Hospital São Rafael, Salvador, Bahia, Brasil
Published: December 2020

Fundamento: O acidente vascular encefálico (AVE) é prevalente no mundo. Reconhecimento precoce da doença cardiovascular subclínica pode predizer um primeiro episódio de AVE isquêmico; o speckle tracking associado à ecocardiografia (STE) permite detecção precoce da disfunção miocárdica subclínica. Objetivo: Provar a associação entre deformação miocárdica avaliada pelo STE e primeiro episódio de AVE em indivíduos saudáveis. Método: Incluímos participantes entre 40-80 anos com primeiro episódio de AVE isquêmico sem cardiopatia conhecida, pareados por sexo, idade e hipertensão com grupo controle saudável na proporção 1:2. STE avaliou strain longitudinal (SL) do ventrículo esquerdo (VE), e ecocardiografia tradicional foi realizada. Análises univariada e multivariada avaliaram as relações do AVE com fatores de risco cardiovasculares e parâmetros derivados da ecocardiografia. Resultado: 29 casos e 62 controles foram incluídos. Média etária foi 60 ± 12 anos; 54% eram homens. Tabagismo foi mais prevalente em casos do que em controles (34% vs. 9%; p=0.001). Nenhum outro fator de risco evidenciou diferença estatística. Casos tiveram menor deformação miocárdica comparados aos controles (SL -16.7 ± 3.4% vs. -19.2 ± 2.8%; p < 0.001). Não houve diferença em relação aos parâmetros ecocardiográficos tradicionais. Após ajuste para tabagismo e hiperlipidemia, SL manteve-se independentemente associado com AVE (OR=1.3; 95% CI, 1.1 – 1.6; p=0.005). A área abaixo à curva ROC para AVE aumentou significativamente após adicionar SL ao tabagismo (0.65 para 0.78, respectivamente; p=0.009). Conclusão: SL tem independente associação com o primeiro episódio de AVE isquêmico em adultos de média idade com corações geralmente normais. SL pode ser potencial marcador de risco nesta população.
Análise da Segurança e Exequibilidade do Ecocardiograma sob Estresse com Dobutamina em Dez Mil e Seis Exames de uma População Geral
Authors:   Clinicárdio Métodos Diagnósticos, Fortaleza, CE, Brasil, de Abreu José Sebastião ,   Cardioexata de Fortaleza, Fortaleza, CE, Brasil, Diógenes Pinheiro Tereza Cristina ,   Clinicárdio Métodos Diagnósticos, Fortaleza, CE, Brasil,   Cardioexata de Fortaleza, Fortaleza, CE, Brasil, Benevides de Abreu Marília Esther ,   Clinicárdio Métodos Diagnósticos, Fortaleza, CE, Brasil,   Cardioexata de Fortaleza, Fortaleza, CE, Brasil, Liberato Ponte Farias Ana Gardenia ,   Cardioexata de Fortaleza, Fortaleza, CE, Brasil,   Hospital das Clínicas, Universidade Federal do Ceará, Ceará, CE, Brasil, Carneiro Marcia Maria ,   Cardioexata de Fortaleza, Fortaleza, CE, Brasil,   Hospital das Clínicas, Universidade Federal do Ceará, Ceará, CE, Brasil
Published: December 2020

Fundamento: Durante o ecocardiograma sob estresse com dobutamina, podem ocorrer efeitos adversos e exames inconclusivos. Objetivo: Avaliar em uma grande população geral a segurança e a exequibilidade do ecocardiograma sob estresse com dobutamina. Métodos: Estudo de 10.006 ecocardiogramas sob estresse com dobutamina realizados no período de julho de 1996 a setembro de 2007. A dobutamina foi administrada em quatro estágios (10, 20, 30 e 40 μcg.kg-1.min-1) para pesquisa de isquemia miocárdica e iniciada com 5 μcg.kg- ¹.min-1 apenas na análise de viabilidade miocárdica. A atropina foi iniciada conforme os protocolos vigentes. Foram verificados dados clínicos, hemodinâmicos e efeitos adversos associados ao ecocardiograma sob estresse com dobutamina. Resultados: Durante os ecocardiogramas sob estresse com dobutamina, ocorreu angina típica (8,9%), pico hipertensivo (1,7%), ectopias ventriculares isoladas (31%), taquiarritmia supraventricular (1,89%), fibrilação atrial (0,76%) e taquicardia ventricular não sustentada (0,6%). Os efeitos adversos citados foram mais frequentes nos pacientes com ecocardiogramas sob estresse com dobutamina positivos para isquemia. A desaceleração sinusal paradoxal (0,16%) não ocorreu em ecocardiogramas sob estresse com dobutamina positivo. As três complicações graves ocorreram em ecocardiogramas sob estresse com dobutamina positivos para isquemia. Foram dois casos (0,02%) com fibrilação ventricular e um caso de síndrome coronariana aguda (0,01%). Não houve caso de taquicardia ventricular sustentada, ruptura cardíaca, assistolia ou óbito. Comparados aos exames concluídos, nos inconclusivos, os pacientes usaram menos atropina (81,5% versus 49,9%; p< 0,001) e mais betabloqueador (4,7% versus 19%; p< 0,001), apresentando mais pico hipertensivo (1,1% versus 14,2%; p = 0,0001) e taquicardia ventricular não sustentada (0,5% versus 2,2%; p< 0,001). Conclusão: O ecocardiograma sob estresse com dobutamina realizado de forma apropriada é seguro e apresenta elevada exequibilidade.