bluuebunny/crossref_metadata_2025 huggingface dataset:
Older Worker Identity and Job Performance: The Moderator Role of Subjective Age and Self-Efficacy
Authors: Rodríguez-Cifuentes Francisco , Farfán Jesús , Topa Gabriela
Published: December 2018

Older Worker Identity consists of the internalization of negative beliefs and attitudes towards aged employees by these same people. This research aims to explore the moderator role both of subjective age and self-efficacy in the relationship between older worker identity and job performance. The study was conducted with a panel design, including a sample of +40 Spanish workers (n = 200), with two waves (4-months interval). The findings supported the moderator role of subjective age in the relationship, while it failed to support the moderator role of self-efficacy. These findings underline that workers who actively manage their subjective age perceptions could age successfully at work. The implications of this study for counseling practices are discussed.
Differential Metabolic Responses to Adipose Atrophy Associated with Cancer Cachexia and Caloric Restriction in Rats and the Effect of Rikkunshito in Cancer Cachexia
Authors: Sudo Yuka , Otsuka Hiroki , Miyakawa Ryota , Goto Akifumi , Kashiwase Yohei , Terawaki Kiyoshi , Miyano Kanako , Hirao Yuto , Taki Kanari , Tagawa Ryoma , Kobayashi Masaki , Okita Naoyuki , Uezono Yasuhito , Higami Yoshikazu
Published: December 2018

Despite the similar phenotypes, including weight loss, reduction of food intake, and lower adiposity, associated with caloric restriction (CR) and cancer cachexia (CC), CC is a progressive wasting syndrome, while mild CR improves whole body metabolism. In the present study, we compared adipose metabolic changes in a novel rat model of CC, mild CR (70% of the food intake of control rats, which is similar to the food consumption of CC rats), and severe CR (30% of the food intake of controls). We show that CC and severe CR are associated with much smaller adipocytes with significantly lower mitochondrial DNA content; but, that mild CR is not. CC and both mild and severe CR similarly upregulated proteins involved in lipolysis. CC also downregulated proteins involved in fatty acid biosynthesis, but mild CR upregulated these. These findings suggest that CC might impair de novo fatty acid biosynthesis and reduce mitochondrial biogenesis, similar to severe CR. We also found that rikkunshito, a traditional Japanese herbal medicine, does not ameliorate the enhanced lipolysis and mitochondrial impairment, but rather, rescues de novo fatty acid biosynthesis, suggesting that rikkunshito administration might have partially similar effects to mild CR.
The Role of Tumor Necrosis Factor α in the Biology of Uterine Fibroids and the Related Symptoms
Authors: Ciebiera Michał , Włodarczyk Marta , Zgliczyńska Magdalena , Łukaszuk Krzysztof , Męczekalski Błażej , Kobierzycki Christopher , Łoziński Tomasz , Jakiel Grzegorz
Published: December 2018

Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The incidence of UFs has been estimated at 25–80% depending on selected population. The pathophysiology of UFs remains poorly understood. The transformation of smooth muscle cells of the uterus into abnormal, immortal cells, capable of clonal division, is the main component of all pathways leading to UF tumor formation and tumor necrosis factor α (TNF-α) is believed to be one of the key factors in this field. TNF-α is a cell signaling protein involved in systemic inflammation and is one of the cytokines responsible for the acute phase reaction. This publication presents current data about the role of tumor necrosis factor α in the biology of UFs and the related symptoms. TNF-α is an extremely important cytokine associated with the biology of UFs, UF-related symptoms and complaints. Its concentration has been proven to be elevated in women with clinically symptomatic UFs. The presented data suggest the presence of an “inflammation-like” state in women with UFs where TNF-α is a potent inflammation inducer. The origin of numerous symptoms reported by women with UFs can be traced back to the TNF-α influence. Nevertheless, our knowledge on this subject remains limited and TNF-α dependent pathways in UF pathophysiology should be investigated further.
Fibroinflammatory Liver Injuries as Preneoplastic Condition in Cholangiopathies
Authors: Cannito Stefania , Milani Chiara , Cappon Andrea , Parola Maurizio , Strazzabosco Mario , Cadamuro Massimiliano
Published: December 2018

The cholangipathies are a class of liver diseases that specifically affects the biliary tree. These pathologies may have different etiologies (genetic, autoimmune, viral, or toxic) but all of them are characterized by a stark inflammatory infiltrate, increasing overtime, accompanied by an excess of periportal fibrosis. The cellular types that mount the regenerative/reparative hepatic response to the damage belong to different lineages, including cholagiocytes, mesenchymal and inflammatory cells, which dynamically interact with each other, exchanging different signals acting in autocrine and paracrine fashion. Those messengers may be proinflammatory cytokines and profibrotic chemokines (IL-1, and 6; CXCL1, 10 and 12, or MCP-1), morphogens (Notch, Hedgehog, and WNT/β-catenin signal pathways) and finally growth factors (VEGF, PDGF, and TGFβ, among others). In this review we will focus on the main molecular mechanisms mediating the establishment of a fibroinflammatory liver response that, if perpetuated, can lead not only to organ dysfunction but also to neoplastic transformation. Primary Sclerosing Cholangitis and Congenital Hepatic Fibrosis/Caroli’s disease, two chronic cholangiopathies, known to be prodrome of cholangiocarcinoma, for which several murine models are also available, were also used to further dissect the mechanisms of fibroinflammation leading to tumor development.
Bioactive Nanoparticles for Cancer Immunotherapy
Authors: Poilil Surendran Suchithra , Moon Myeong Ju , Park Rayoung , Jeong Yong Yeon
Published: December 2018

Currently, immunotherapy is considered to be one of the effective treatment modalities for cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to the interest for research into this vast area of study. Targeting tumor environment as well as the immune system is a suitable strategy to be applied for cancer treatment. Usage of nanoparticle systems for delivery of immunotherapeutic agents to the body being widely studied and found to be a promising area of research to be considered and investigated further. Nanoparticles for immunotherapy would be one of the effective treatment options for cancer therapy in the future due to their high specificity, efficacy, ability to diagnose, imaging, and therapeutic effect. Among the many nanoparticle systems, polylactic-co-glycolic acid (PLGA) nanoparticles, liposomes, micelles, gold nanoparticles, iron oxide, dendrimers, and artificial exosomes are widely used for immunotherapy of cancer. Moreover, the combination therapy found to be the more effective way of treating the tumor. Here, we review the current trends in nanoparticle therapy and efficiency of these nanosystems in delivering antigens, adjuvants, therapeutic drugs, and other immunotherapeutic agents. This review summarizes the currently available bioactive nanoparticle systems for cancer immunotherapy.
Genetic Polymorphisms Associated with Spontaneous Intracerebral Hemorrhage
Authors: Chen Yi-Chun , Chang Kuo-Hsuan , Chen Chiung-Mei
Published: December 2018

Differences in the incidence of spontaneous intracerebral hemorrhage (ICH) between ethnicities exist, with an estimated 42% of the variance explained by ethnicity itself. Caucasians have a higher proportion of lobar ICH (LICH, 15.4% of all ICH) than do Asians (3.4%). Alterations in the causal factor exposure between countries justify part of the ethnic variance in ICH incidence. One third of ICH risk can be explained by genetic variation; therefore, genetic differences between populations can partly explain the difference in ICH incidence. In this paper, we review the current knowledge of genetic variants associated with ICH in multiple ethnicities. Candidate gene variants reportedly associated with ICH were involved in the potential pathways of hypertension, vessel wall integrity, lipid metabolism, endothelial dysfunction, inflammation, platelet function, and coagulopathy. Furthermore, variations in APOE (in multiple ethnicities), PMF1/SLC25A44 (in European), ACE (in Asian), MTHFR (in multiple ethnicities), TRHDE (in European), and COL4A2 (in European) were the most convincingly associated with ICH. The majority of the associated genes provide small contributions to ICH risk, with few of them being replicated in multiple ethnicities.
Improving the Accuracy in Sentiment Classification in the Light of Modelling the Latent Semantic Relations
Authors: Rizun Nina , Taranenko Yurii , Waloszek Wojciech
Published: December 2018

The research presents the methodology of improving the accuracy in sentiment classification in the light of modelling the latent semantic relations (LSR). The objective of this methodology is to find ways of eliminating the limitations of the discriminant and probabilistic methods for LSR revealing and customizing the sentiment classification process (SCP) to the more accurate recognition of text tonality. This objective was achieved by providing the possibility of the joint usage of the following methods: (1) retrieval and recognition of the hierarchical semantic structure of the text and (2) development of the hierarchical contextually-oriented sentiment dictionary in order to perform the context-sensitive SCP. The main scientific contribution of this research is the set of the following approaches: at the phase of LSR revealing (1) combination of the discriminant and probabilistic models while applying the rules of adjustments to obtain the final joint result; at all SCP phases (2) considering document as a complex structure of topically completed textual components (paragraphs) and (3) taking into account the features of persuasive documents’ type. The experimental results have demonstrated the enhancement of the SCP accuracy, namely significant increase of average values of recall and precision indicators and guarantee of sufficient accuracy level.
Fluorolytic Sol–Gel Synthesis of Nanometal Fluorides: Accessing New Materials for Optical Applications
Authors: Scheurell Kerstin , Kemnitz Erhard
Published: December 2018

The potential of fluorolytic sol–gel synthesis for a wide variety of applications in the field of optical materials is reviewed. Based on the fluorolytic sol–gel synthesis of nanometal fluorides, sols of complex fluorometalates have become available that exhibit superior optical properties over known classical binary metal fluorides as, for instance, magnesium fluoride, calcium fluoride, or strontium fluoride, respectively. The synthesis of transparent sols of magnesium fluoroaluminates of the general composition MgxAlFy, and fluoroperovskites, [K1−xNax]MgF3, is reported. Antireflective coatings fabricated from MgF2, CaF2, MgxAlFy, and [K1−xNax]MgF3 sols and their relevant properties are comprehensively described. Especially the heavier alkaline earth metal fluorides and the fluorperovskites crystallizing in a cubic crystal structure are excellent hosts for rare earth (RE) metals. Thus, the second chapter reflects the synthesis approach and the properties of luminescent systems based on RE-doped alkaline earth metal fluorides and [K1−xNax]MgF3 phases.
A Study of the Effects of Hf and Sn on the Microstructure, Hardness and Oxidation of Nb-18Si Silicide Based Alloys without Ti Addition
Authors: Zacharis Eleftherios , Utton Claire , Tsakiropoulos Panos
Published: December 2018

The paper presents the results of an experimental study of large (≈0.6 kg) arc melted buttons of four Ti free Nb-silicide based alloys with Sn addition with nominal compositions (at.%) Nb-18Si-5Hf-5Sn (EZ1), Nb-18Si-5Al-5Sn (EZ7), Nb-18Si-5Cr-5Hf-5Sn (EZ3) and Nb-18Si-5Al-5Hf-5Sn (EZ4). The alloys were studied in the as-cast and heat treated conditions. In all the alloys there was macrosegregation of Si (MACSi). Among the single element additions Hf had the weakest and Sn the strongest effect on MACSi. The simultaneous presence of Cr and Hf in the alloy EZ3 had the strongest effect on MACSi. In all the alloys the βNb5Si3 was the primary phase and was present after the heat treatment(s), the Nb3Si silicide was suppressed and the A15-Nb3Sn intermetallic was stable. The Nbss was not stable in the alloys EZ7 and EZ4 and the C14-NbCr2 Laves phase was stable in the alloy EZ3. Very Hf-rich Nb5Si3 was stable in the alloy EZ4 after prolonged heat treatments. Eutectics were observed in all the alloys. These were binary eutectics in the alloys EZ1 and EZ7, where respectively they consisted of the Nbss and βNb5Si3, and βNb5Si3 and A15-Nb3Sn phases. Most likely ternary eutectics consisting of the Nbss, C14-NbCr2 and βNb5Si3, and Nbss, βNb5Si3 and A15-Nb3Sn phases were observed, respectively in the alloys EZ3 and EZ4. The addition of Al increased the vol% of the Nb5Si3 and A15-Nb3Sn phases, particularly after the heat treatment(s). The lattice parameter of Nb respectively increased and decreased with the addition of Hf, and Al or Cr and the latter element had the stronger negative effect. Pest oxidation was not suppressed in the alloys of this study.
Transparent Metasurface for Generating Microwave Vortex Beams with Cross-Polarization Conversion
Authors: Shi Hongyu , Wang Luyi , Zhao Mengran , Chen Juan , Zhang Anxue , Xu Zhuo
Published: December 2018

In this paper, metasurfaces with both cross-polarization conversion and vortex beam-generating are proposed. The proposed finite metasurface designs are able to change the polarization of incident electromagnetic (EM) waves to its cross-polarization. In addition, they also can modulate the incidences into beams carrying orbital angular momentum (OAM) with different orders ( l = + 1 , l = + 2 , l = − 1 and l = − 2 ) by applying corresponding transmission phase distribution schemes on the metasurface aperture. The generated vortex beams are at 5.14 GHz. The transmission loss is lower than 0.5 dB while the co-polarization level is −10 dB compared to the cross-polarization level. The measurement results confirmed the simulation results and verified the properties of the proposed designs.
Experimental Evaluation of Interfacial Surface Cracks in Friction Welded Dissimilar Metals through Image Segmentation Technique (IST)
Authors: Sayeed Ahmed Gulam Mohammed , Algahtani Ali , Mahmoud Essam R. I. , Badruddin Irfan Anjum
Published: December 2018

Surface cracks on the friction welded interface of dissimilar metals are one of the earliest indications of degradation of the joint, which is a critical aspect for the welding strength. By manual inspection of the friction welded joint, observations of irregularities, porosity voids, crack lengths, cracked surfaces, and depth penetrations of two dissimilar metals can be made. Manual inspection purely depends on a quality expert’s experience of quantitative analysis and knowledge. In this research, an attempt has been made to effectively utilize the image segmentation technique (IST) in the estimation of the welded surface quality of a dissimilar joint by friction welding. The bonding strength between dissimilar metals in friction welding is more dependent on the coefficient of friction between the metallic surfaces. To demonstrate the capability of the image segmentation technique, experiments were conducted with various parameters, such as friction pressure, friction time, coefficient of friction, and torque speed of the rotating work piece. The effect of the coefficient of friction on friction welded surface quality by considering process parameters is estimated by using the proposed technique. Experiments were validated and the results claimed that the proposed image processing approach is efficient in fractured surface crack detection, reducing the computation cost, and providing a high-speed method with greater accuracy in the identification of welded surface defects. It was found that the friction coefficient is dependent mostly on the friction pressure and friction time. Its values range from 0.21 to 0.71, with the highest value of friction pressure at 120 MPa and 500 rpm. The present work deals with the detection of welding defects by means of segmentation based analysis of the welded interface. This method has a significant improvement in the fractured surface, crack detection, and non-welded areas’ detection in terms of pixels at the desired region, and is easy when compared to conventional detection techniques by using an operator’s decisions.
Direct van der Waals Epitaxy of Crack-Free AlN Thin Film on Epitaxial WS2
Authors: Yin Yue , Ren Fang , Wang Yunyu , Liu Zhiqiang , Ao Jinping , Liang Meng , Wei Tongbo , Yuan Guodong , Ou Haiyan , Yan Jianchang , Yi Xiaoyan , Wang Junxi , Li Jinmin
Published: December 2018

Van der Waals epitaxy (vdWE) has drawn continuous attention, as it is unlimited by lattice-mismatch between epitaxial layers and substrates. Previous reports on the vdWE of III-nitride thin film were mainly based on two-dimensional (2D) materials by plasma pretreatment or pre-doping of other hexagonal materials. However, it is still a huge challenge for single-crystalline thin film on 2D materials without any other extra treatment or interlayer. Here, we grew high-quality single-crystalline AlN thin film on sapphire substrate with an intrinsic WS2 overlayer (WS2/sapphire) by metal-organic chemical vapor deposition, which had surface roughness and defect density similar to that grown on conventional sapphire substrates. Moreover, an AlGaN-based deep ultraviolet light emitting diode structure on WS2/sapphire was demonstrated. The electroluminescence (EL) performance exhibited strong emissions with a single peak at 283 nm. The wavelength of the single peak only showed a faint peak-position shift with increasing current to 80 mA, which further indicated the high quality and low stress of the AlN thin film. This work provides a promising solution for further deep-ultraviolet (DUV) light emitting electrodes (LEDs) development on 2D materials, as well as other unconventional substrates.
Preparation of Nano-SiO2/Al2O3/ZnO-Blended PVDF Cation-Exchange Membranes with Improved Membrane Permselectivity and Oxidation Stability
Authors: Zhang Xuemin , Zhou Jian , Zou Xin , Wang Zhongyu , Chu Yunchen , Wang Sanfan
Published: December 2018

Ion exchange membranes are used in practically every industry; however, most of them have defects such as low permeability and poor oxidation resistance. In this paper, cation-exchange membranes were prepared with poly (vinylidene fluoride) (PVDF) blended with nano-SiO2, nano-Al2O3 and nano-ZnO. Sulfonic acid groups were injected into the membrane prepared by styrene grafting and sulfonation. The methods used for characterizing the prepared membranes were Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and electrochemical measurements. Membrane performance, such as the ion exchange capacity (IEC), water uptake (WU), transport number, membrane permselectivity, membrane resistance, functional groups, and morphology were also evaluated. The hydrophilia, IEC, and permselectivity of cation-exchange membranes depended on the nanoparticle content of the membrane matrix. High transport property values were obtained, which increased with increasing nano-SiO2/Al2O3/ZnO weight fractions. Finally, the cation-exchange membranes prepared with 1.5% nano-SiO2, 2.0% nano-Al2O3 or 2.0% nano-ZnO all exhibited excellent membrane properties, including membrane permselectivity (PVDF/2% ZnO-g-PSSA membranes, 94.9%), IEC (PVDF/2% Al2O3-g-PSSA membranes, 2.735 mmol·g−1), and oxidation resistance (PVDF/1.5% SiO2-g-PSSA membranes, 2.33%). They can be used to separate applications in a variety of different areas, such as water treatment, electro-driven separation, heavy metal smelting, or other electrochemical processes.
Some Identities Involving the Fubini Polynomials and Euler Polynomials
Authors: Chen Guohui , Chen Li
Published: December 2018

In this paper, we first introduce a new second-order non-linear recursive polynomials U h , i ( x ) , and then use these recursive polynomials, the properties of the power series and the combinatorial methods to prove some identities involving the Fubini polynomials, Euler polynomials and Euler numbers.
Construction Algorithm for Zero Divisor Graphs of Finite Commutative Rings and Their Vertex-Based Eccentric Topological Indices
Authors: Elahi Kashif , Ahmad Ali , Hasni Roslan
Published: December 2018

Chemical graph theory is a branch of mathematical chemistry which deals with the non-trivial applications of graph theory to solve molecular problems. Graphs containing finite commutative rings also have wide applications in robotics, information and communication theory, elliptic curve cryptography, physics, and statistics. In this paper we discuss eccentric topological indices of zero divisor graphs of commutative rings Z p 1 p 2 × Z q , where p 1 , p 2 , and q are primes. To enhance the importance of these indices a construction algorithm is also devised for zero divisor graphs of commutative rings Z p 1 p 2 × Z q .
Marine Biomaterial-Based Bioinks for Generating 3D Printed Tissue Constructs
Authors: Zhang Xiaowei , Kim Gyeong Jin , Kang Min Gyeong , Lee Jung Ki , Seo Jeong Wook , Do Jeong Tae , Hong Kwonho , Cha Jae Min , Shin Su Ryon , Bae Hojae
Published: December 2018

Biologically active materials from marine sources have been receiving increasing attention as they are free from the transmissible diseases and religious restrictions associated with the use of mammalian resources. Among various other biomaterials from marine sources, alginate and fish gelatin (f-gelatin), with their inherent bioactivity and physicochemical tunability, have been studied extensively and applied in various biomedical fields such as regenerative medicine, tissue engineering, and pharmaceutical products. In this study, by using alginate and f-gelatin’s chemical derivatives, we developed a marine-based interpenetrating polymer network (IPN) hydrogel consisting of alginate and f-gelatin methacryloyl (f-GelMA) networks via physical and chemical crosslinking methods, respectively. We then evaluated their physical properties (mechanical strength, swelling degree, and degradation rate) and cell behavior in hydrogels. Our results showed that the alginate/f-GelMA hydrogel displayed unique physical properties compared to when alginate and f-GelMA were used separately. These properties included high mechanical strength, low swelling and degradation rate, and an increase in cell adhesive ability. Moreover, for the first time, we introduced and optimized the application of alginate/f-GelMA hydrogel in a three-dimensional (3D) bioprinting system with high cell viability, which breaks the restriction of their utilization in tissue engineering applications and suggests that alginate/f-GelMA can be utilized as a novel bioink to broaden the uses of marine products in biomedical fields.
Impact of Blood Collection Tubes and Sample Handling Time on Serum and Plasma Metabolome and Lipidome
Authors: Cruickshank-Quinn Charmion , Zheng Laura K. , Quinn Kevin , Bowler Russell , Reisdorph Richard , Reisdorph Nichole
Published: December 2018

Background: Metabolomics is emerging as a valuable tool in clinical science. However, one major challenge in clinical metabolomics is the limited use of standardized guidelines for sample collection and handling. In this study, we conducted a pilot analysis of serum and plasma to determine the effects of processing time and collection tube on the metabolome. Methods: Blood was collected in 3 tubes: Vacutainer serum separator tube (SST, serum), EDTA (plasma) and P100 (plasma) and stored at 4 degrees for 0, 0.5, 1, 2, 4 and 24 h prior to centrifugation. Compounds were extracted using liquid-liquid extraction to obtain a hydrophilic and a hydrophobic fraction and analyzed using liquid chromatography mass spectrometry. Differences among the blood collection tubes and sample processing time were evaluated (ANOVA, Bonferroni FWER ≤ 0.05 and ANOVA, Benjamini Hochberg FDR ≤ 0.1, respectively). Results: Among the serum and plasma tubes 93.5% of compounds overlapped, 382 compounds were unique to serum and one compound was unique to plasma. There were 46, 50 and 86 compounds affected by processing time in SST, EDTA and P100 tubes, respectively, including many lipids. In contrast, 496 hydrophilic and 242 hydrophobic compounds differed by collection tube. Forty-five different chemical classes including alcohols, sugars, amino acids and prenol lipids were affected by the choice of blood collection tube. Conclusion: Our results suggest that the choice of blood collection tube has a significant effect on detected metabolites and their overall abundances. Perhaps surprisingly, variation in sample processing time has less of an effect compared to collection tube; however, a larger sample size is needed to confirm this.
Scalalactams A–D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge
Authors: Yang Inho , Lee Jusung , Lee Jihye , Hahn Dongyup , Chin Jungwook , Won Dong Hwan , Ko Jaeyoung , Choi Hyukjae , Hong Ahreum , Nam Sang-Jip , Kang Heonjoong
Published: December 2018

Intensive study on the chemical components of a Korean marine sponge, Spongia sp., has led to the isolation of four new scalarane sesterterpenes, scalalactams A–D (1–4). Their chemical structures were elucidated from the analysis of spectroscopic data including 1D-and 2D-NMR as well as MS data. Scalalactams A–D (1–4) possess a scalarane carbon skeleton with a rare structural feature of a γ-lactam moiety within the molecules. Scalalactams A and B (1 and 2) have an extended isopropanyl chain at the lactam ring, and scalalactams C and D (3 and 4) possess a phenethyl group at the lactam ring moiety. Scalalactams A–D (1–4) did not show FXR antagonistic activity nor cytotoxicity up to 100 μM.
Graphene Reinforced Composites as Protective Coatings for Oil and Gas Pipelines
Authors: Wang Xingyu , Qi Xiaoning , Lin Zhibin , Battocchi Dante
Published: December 2018

Corrosion and corrosion-induced damage have resulted mostly in malfunctions and sometimes even in failures of metallic structures, including oil and gas pipelines. In this study, new high-performance composite coatings were developed by incorporating nanoparticles in the polymer resins with applications to oil and gas pipelines. The graphene nanoplatelets under different concentrations were used to prepare the epoxy-based nanocomposites and were then evaluated through mechanical and electrical tests. The integration of high-speed disk and ultrasonication were adopted as the dispersion technique to overcome nanoparticle agglomeration. Electron microscopy techniques were used to investigate the agglomeration. The new composites were qualitatively and quantitatively evaluated in terms of contact angle, surface roughness, adhesion to the substrate, corrosion resistance, and abrasion resistance. The results suggested that the composite with 0.5~1.0 wt.% of the graphene nanofillers led to the largest improvement in both mechanical and electrochemical properties. Distribution of nanoparticles in the matrix was observed using scanning electron microscopy and surface roughness using atomic force microscopy. Large agglomeration that was observed at the higher concentrations mainly resulted in the reduction of corrosion resistance and abrasion resistance.
Breast Milk Macronutrient Components in Prolonged Lactation
Authors: Czosnykowska-Łukacka Matylda , Królak-Olejnik Barbara , Orczyk-Pawiłowicz Magdalena
Published: December 2018

Human milk (HM) is the first dietary exposure in infancy and the best nutritional option for growth and healthy development of the newborn and infant. The concentrations of macronutrients, namely proteins, carbohydrates and lipids, change during lactation stages. HM has been studied extensively in the first 6 months of lactation, but there are limited data regarding milk composition beyond 1 or 2 years postpartum. The aim of our study was to describe longitudinal changes in HM macronutrient concentrations during the prolonged lactation of healthy mothers from the 1st to the 48th month. For the macronutrient content of milk of mothers breastfeeding for longer than 18 months, fat and protein increased and carbohydrates decreased significantly, compared with milk expressed by women breastfeeding up to 12 months. Moreover, the concentration of fat, protein and carbohydrates in HM over 2 years of lactation from the 24th to the 48th month remained at a stable level. However, analyzed macronutrients were positively (carbohydrate, r = 0.51) or negatively (fat, r = −0.36 and protein, r = −0.58) correlated with the amount of feeding. Our results create a greater potential for understanding the nutritional contribution of HM over 2 years of lactation and showed that the source of calories in breast milk for older children is mainly fat, while carbohydrates play a greater role in infant nutrition in the early stage. The observed changes of macronutrient concentrations from the 1st to the 48th month of lactation are probably related to the adaptation of milk composition to the increased energy demand of the intensively growing child.
Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
Authors: Sasaki Hiromi , Nagano Satoshi , Taniguchi Noboru , Setoguchi Takao
Published: December 2018

Malignant soft-tissue sarcoma resection is associated with a relatively high incidence of surgical site infection (SSI). The known risk factors for SSI following soft-tissue sarcoma resection include tumor size and location, prolonged surgery, and massive blood loss. The geriatric nutritional risk index (GNRI) was used as a tool to help predict the occurrence of SSI after major surgery. We investigated the utility of the GNRI as a predictor of SSI following soft-tissue sarcoma resection. We retrospectively reviewed 152 patients who underwent surgical resection of soft-tissue sarcoma in our institute, and found that the incidence of SSI was 18.4% (28/152). The SSI and non-SSI groups significantly differed regarding surgical time, diameter of the skin incision, maximum tumor diameter, instrumentation, presence of an open wound, preoperative chemotherapy, preoperative C-reactive protein concentration, and GNRI. Binomial logistic regression analysis showed that the risk factors for SSI following soft-tissue sarcoma surgery were male sex, larger skin incision diameter, larger maximum tumor diameter, presence of an open wound, and lower GNRI. Our findings indicate that malnutrition is a risk factor for SSI after soft-tissue sarcoma resection, and suggest that appropriate assessment and intervention for malnutrition may reduce the incidence of SSI.
Active Image-Assisted Food Records in Comparison to Regular Food Records: A Validation Study against Doubly Labeled Water in 12-Month-Old Infants
Authors: Johansson Ulrica , Venables Michelle , Öhlund Inger , Lind Torbjörn
Published: December 2018

Overreporting of dietary intake in infants is a problem when using food records (FR), distorting possible relationships between diet and health outcomes. Image-assisted dietary assessment may improve the accuracy, but to date, evaluation in the pediatric setting is limited. The aim of the study was to compare macronutrient and energy intake by using an active image-assisted five-day FR against a regular five-day FR, and to validate image-assistance with total energy expenditure (TEE), was measured using doubly labeled water. Participants in this validation study were 22 healthy infants randomly selected from the control group of a larger, randomized intervention trial. The parents reported the infants’ dietary intake, and supplied images of main course meals taken from standardized flat-surfaced plates before and after eating episodes. Energy and nutrient intakes were calculated separately using regular FR and image-assisted FRs. The mean (± standard deviations) energy intake (EI) was 3902 ± 476 kJ/day from the regular FR, and 3905 ± 476 kJ/day from the FR using active image-assistance. The mean EI from main-course meals when image-assistance was used did not differ (1.7 ± 55 kJ, p = 0.89) compared to regular FRs nor did the intake of macronutrients. Compared to TEE, image-assisted FR overestimated EI by 10%. Without validation, commercially available software to aid in the volume estimations, food item identification, and automation of the image processing, image-assisted methods remain a more costly and burdensome alternative to regular FRs in infants. The image-assisted method did, however, identify leftovers better than did regular FR, where such information is usually not readily available.
Three-Year Chronic Consumption of Low-Carbohydrate Diet Impairs Exercise Performance and Has a Small Unfavorable Effect on Lipid Profile in Middle-Aged Men
Authors: Pilis Karol , Pilis Anna , Stec Krzysztof , Pilis Wiesław , Langfort Józef , Letkiewicz Sławomir , Michalski Cezary , Czuba Miłosz , Zych Michał , Chalimoniuk Małgorzata
Published: December 2018

The objective of this research was to determine whether chronic (average 3.58 ± 1.56 years) deliberate adherence to low carbohydrate diets (LCDs) is associated with selected markers of metabolism, risk factors of cardiovascular disease (CVD), body mass and physical performance in apparently healthy middle-aged men (n = 12). The control group comprised age, body mass and height matched men using mixed diets (MDs). The diets used were registered for 7 days and analyzed in terms of the energy, carbohydrate, fat and protein contents. It was found that the diets used were isoenergetic, yet varied considerably in carbohydrate and fat content. The LCDs significantly intensified the ketogenesis process, increased resting blood total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and heart rate, (HR) and decreased respiratory exchange ratio (RER) in relation to MD subjects. An exercise trial revealed significant impairment of exercise in subjects following the LCDs. The results showed that in the case where the subjects of two investigated groups did not differ in their somatic variables, long-term adherence to the LCDs was associated with substantially reduced exercise performance in apparently healthy subjects, along with an association with a small unfavorable effect on their lipid profile.
Vitamin E Metabolic Effects and Genetic Variants: A Challenge for Precision Nutrition in Obesity and Associated Disturbances
Authors: Galmés Sebastià , Serra Francisca , Palou Andreu
Published: December 2018

Vitamin E (VE) has a recognized leading role as a contributor to the protection of cell constituents from oxidative damage. However, evidence suggests that the health benefits of VE go far beyond that of an antioxidant acting in lipophilic environments. In humans, VE is channeled toward pathways dealing with lipoproteins and cholesterol, underlining its relevance in lipid handling and metabolism. In this context, both VE intake and status may be relevant in physiopathological conditions associated with disturbances in lipid metabolism or concomitant with oxidative stress, such as obesity. However, dietary reference values for VE in obese populations have not yet been defined, and VE supplementation trials show contradictory results. Therefore, a better understanding of the role of genetic variants in genes involved in VE metabolism may be crucial to exert dietary recommendations with a higher degree of precision. In particular, genetic variability should be taken into account in targets concerning VE bioavailability per se or concomitant with impaired lipoprotein transport. Genetic variants associated with impaired VE liver balance, and the handling/resolution of oxidative stress might also be relevant, but the core information that exists at present is insufficient to deliver precise recommendations.
Effect of Low-Temperature Pyrolysis on the Properties of Jute Fiber-Reinforced Acetylated Softwood Kraft Lignin-Based Thermoplastic Polyurethane
Authors: Roh Hyun-gyoo , Kim Sunghoon , Lee Jungmin , Park Jongshin
Published: December 2018

Short jute fiber-reinforced acetylated lignin-based thermoplastic polyurethane (JF reinforced ASKLTPU) was prepared and characterized as a short-fiber-reinforced elastomer with carbon-neutrality and biodegradability. The acetylated softwood kraft lignin-based thermoplastic polyurethane (ASKLTPU) was prepared with polyethylene glycol (PEG) as a soft segment. Short jute fiber was modified using low-temperature pyrolysis up to the temperatures of 200, 250, and 300 °C in order to remove non-cellulosic compounds of jute fibers for enhancing interfacial bonding and reducing hydrophilicity with the ASKLTPU matrix. JF-reinforced ASKLTPUs with fiber content from 5 to 30 wt % were prepared using a melt mixing method followed by hot-press molding at 160 °C. The JF-reinforced ASKLTPUs were characterized for their mechanical properties, dynamic mechanical properties, thermal transition behavior, thermal stability, water absorption, and fungal degradability. The increased interfacial bonding between JF and ASKLTPU using low-temperature pyrolysis was observed using scanning electron microscopy (SEM) and also proved via interfacial shear strength measured using a single-fiber pull-out test. The mechanical properties, thermal properties, and water absorption aspects of JF-reinforced ASKLTPU were affected by increased interfacial bonding and reduced hydrophilicity from low-temperature pyrolysis. In the case of the degradation test, the PEG component of ASKLPTU matrix highly affects degradation and deterioration.
Cobalt-Doped Porous Carbon Nanosheets Derived from 2D Hypercrosslinked Polymer with CoN4 for High Performance Electrochemical Capacitors
Authors: Chen Yuanhai , Liu Fengru , Qiu Feng , Lu Chenbao , Kang Jialing , Zhao Doudou , Han Sheng , Zhuang Xiaodong
Published: December 2018

Cobalt-doped graphene-coupled hypercrosslinked polymers (Co-GHCP) have been successfully prepared on a large scale, using an efficient RAFT (Reversible Addition-Fragmentation Chain Transfer Polymerization) emulsion polymerization and nucleophilic substitution reaction with Co (II) porphyrin. The Co-GHCP could be transformed into cobalt-doped porous carbon nanosheets (Co-GPC) through direct pyrolysis treatment. Such a Co-GPC possesses a typical 2D morphology with a high specific surface area of 257.8 m2 g−1. These intriguing properties of transition metal-doping, high conductivity, and porous structure endow the Co-GPC with great potential applications in energy storage and conversion. Utilized as an electrode material in a supercapacitor, the Co-GPC exhibited a high electrochemical capacitance of 455 F g−1 at a specific current of 0.5 A g−1. After 2000 charge/discharge cycles, at a current density of 1 A g−1, the specific capacitance increased by almost 6.45%, indicating the excellent capacitance and durability of Co-GPC. These results demonstrated that incorporation of metal porphyrin into the framework of a hypercrosslinked polymer is a facile strategy to prepare transition metal-doped porous carbon for energy storage applications.
Estimating Soil Evaporation Using Drying Rates Determined from Satellite-Based Soil Moisture Records
Authors: Small Eric E. , Badger Andrew M. , Abolafia-Rosenzweig Ronnie , Livneh Ben
Published: December 2018

We describe an approach (ESMAP; Evaporation–Soil Moisture Active Passive) to estimate direct evaporation from soil, Esoil, by combining remotely-sensed soil drying rates with model calculations of the vertical fluxes in and out of the surface soil layer. Improved knowledge of Esoil can serve as a constraint in how total evapotranspiration is partitioned. The soil drying rates used here are based on SMAP data, but the method could be applied to data from other sensors. We present results corresponding to ten SMAP pixels in North America to evaluate the method. The ESMAP method was applied to intervals between successive SMAP overpasses with limited precipitation (<2 mm) to avoid uncertainty associated with precipitation, infiltration, and runoff. We used the Hydrus 1-D model to calculate the flux of water across the bottom boundary of the 0 to 50 mm soil layer sensed by SMAP, qbot. During dry intervals, qbot typically transfers water upwards into the surface soil layer from below, usually <0.5 mm day−1. Based on a standard formulation, transpiration from the surface soil layer, ET_s, is usually < 0.1 mm day−1, and, thus, generally not an important flux. Soil drying rates (converted to equivalent water thickness) are typically between 0 and 1 mm day−1. Evaporation is almost always greater than soil drying rates because qbot is typically a source of water to the surface soil and ET_s is negligible. Evaporation is typically between 0 and 1.5 mm day−1, with the highest values following rainfall. Soil evaporation summed over SMAP overpass intervals with precipitation <2 mm (60% of days) accounts for 15% of total precipitation. If evaporation rates are similar during overpasses with substantial precipitation, then the total evaporation flux would account for ~25% of precipitation. ESMAP could be used over spatially continuous domains to provide constraints on Esoil, but model-based Esoil would be required during intervals with substantial precipitation.
Design and Analysis of a Quasi-Yagi Antenna for an Indoor Location Tracking System
Authors: Kim Sun-Woong , Noh Sun-Kuk , Yu Ho-Gyun , Choi Dong-You
Published: December 2018

In this paper, a quasi-Yagi antenna for an indoor location tracking system is proposed. The performance of the proposed antenna was verified by testing it using an indoor location tracking system. To improve the bandwidth and gain, two parasitic directors were added near the dipole. The performance verification of the proposed antenna is explained, along with a performance comparison of the VSWR (voltage standing wave ratio) radiation pattern and the realized gain. The proposed antenna was connected to an NVA-R661 module of Xethru Inc. for indoor location tracking. The proposed antenna exhibited a wide bandwidth of 4.36 GHz by satisfying a VSWR ≤ 2 from 5.03 to 9.39 GHz, the maximum gain was 6.46 dBi in the 8 GHz band. The radiation pattern exhibited a good directivity characteristic within the proposed band. The location tracking result of a moving target clearly describes the route of the target along a moving line.
Design of User-Customized Negative Emotion Classifier Based on Feature Selection Using Physiological Signal Sensors
Authors: Lee JeeEun , Yoo Sun K.
Published: December 2018

First, the Likert scale and self-assessment manikin are used to provide emotion analogies, but they have limits for reflecting subjective factors. To solve this problem, we use physiological signals that show objective responses from cognitive status. The physiological signals used are electrocardiogram, skin temperature, and electrodermal activity (EDA). Second, the degree of emotion felt, and the related physiological signals, vary according to the individual. KLD calculates the difference in probability distribution shape patterns between two classes. Therefore, it is possible to analyze the relationship between physiological signals and emotion. As the result, features from EDA are important for distinguishing negative emotion in all subjects. In addition, the proposed feature selection algorithm showed an average accuracy of 92.5% and made it possible to improve the accuracy of negative emotion recognition.
Foreground Detection with Deeply Learned Multi-Scale Spatial-Temporal Features
Authors: Wang Yao , Yu Zujun , Zhu Liqiang
Published: December 2018

Foreground detection, which extracts moving objects from videos, is an important and fundamental problem of video analysis. Classic methods often build background models based on some hand-craft features. Recent deep neural network (DNN) based methods can learn more effective image features by training, but most of them do not use temporal feature or use simple hand-craft temporal features. In this paper, we propose a new dual multi-scale 3D fully-convolutional neural network for foreground detection problems. It uses an encoder–decoder structure to establish a mapping from image sequences to pixel-wise classification results. We also propose a two-stage training procedure, which trains the encoder and decoder separately to improve the training results. With multi-scale architecture, the network can learning deep and hierarchical multi-scale features in both spatial and temporal domains, which is proved to have good invariance for both spatial and temporal scales. We used the CDnet dataset, which is currently the largest foreground detection dataset, to evaluate our method. The experiment results show that the proposed method achieves state-of-the-art results in most test scenes, comparing to current DNN based methods.
Are People from Households with Children More Likely to Travel by Car? An Empirical Investigation of Individual Travel Mode Choices in Shanghai, China
Authors: Ye Nan , Gao Linjie , Juan Zhicai , Ni Anning
Published: December 2018

China is expected to have more children now that its family planning policy has been relaxed, and the influence of children on transportation and sustainability should not be neglected. This study uses econometric methods to explore the impact that the presence of children has on household car ownership, car-travel behavior of family members, and variability in their car-use frequency across weekdays and weekends. Models are estimated using multi-day travel patterns imputed from GPS-enabled smartphone data collected in Shanghai, China. Results indicate that: (1) households with children have more private cars than those without children, and the presence of preschoolers and pupils both increase families’ demand for car ownership; (2) travel behavior of people from households with children is influenced subtly by the children’s presence, which leads them to prefer to travel by car, although the presence of retired or unemployed household members can weaken that influence; and (3) car-travel frequency of individuals is significantly different between weekdays and weekends, with the presence of pupils in the household diminishing that variability and the presence of preschoolers enlarging it. Policymakers and transportation planners should be concerned about these issues and take appropriate measures.
Complex Interrelationships between Ecosystem Services Supply and Tourism Demand: General Framework and Evidence from the Origin of Three Asian Rivers
Authors: Chung Min Gon , Pan Tao , Zou Xintong , Liu Jianguo
Published: December 2018

Over the past two decades, the demands of nature-based tourism have been rapidly growing worldwide, yet it is not clear how tourist demands for water, food, and infrastructure influence the ecosystem services (ES), which are often the bedrock of an area’s economic, cultural, and natural wealth. With a general conceptual model that applies the telecoupling framework, this study identifies complex interrelationships between the demand for nature-based tourism, which is a type of cultural ES, ES supply, and the economy simultaneously, using China’s Qinghai Province as a demonstration site. The province is the origin of three rivers, making it crucial for water retention and prime for tourism. The results indicate that there is a strong spatial interaction between the number of tourism attractions and water retention. The southern Qinghai region’s natural resources are protected by the Sanjiangyuan (three rivers headwater) National Park. From 2010–2014, tourists in the Sanjiangyuan region spent more money than those in the northern Qinghai region, which has accelerated the development of tourism infrastructures. The Sanjiangyuan region may face the unexpected degradation of its natural habitats due to rapid tourism development. Our findings suggest that new management plans are needed to minimize the negative impacts from the demands of distant tourists, and preserve the region that supports both the environment and the economy.