bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case Study of the Glycoside Hydrolase Enzyme Mechanism Using an Automated QM-cluster Model Building Toolkit
Authors: Cheng Qianyi , DeYonker Nathan J.
Published: December 2021

Glycoside hydrolase enzymes are important for hydrolyzing the β-1,4
glycosidic bond in polysaccharides for deconstruction of carbohydrates.
The two-step retaining reaction mechanism was explored with different
sized QM-cluster models built by the Residue Interaction Network ResidUe
Selector (RINRUS) software using both the wild-type protein and its
E217Q mutant. The first step is the glycosylation, in which the acidic
residue 217 donates a proton to the glycosidic oxygen leading to bond
cleavage. In the subsequent deglycosylation step, one water molecule
migrates into the active site and attacks the anomeric carbon. Residue
interaction-based QM-cluster models lead to reliable structural and
energetic results for proposed glycoside hydrolase mechanisms. The free
energies of activation for glycosylation in the largest QM-cluster
models were predicted to be 19.5 and 31.4 kcal mol
for the wild-type protein and its E217Q mutant, which agree with
experimental trends that mutation of the acidic residue Glu217 to Gln
will slow down the reaction, and are higher in free energy than the
deglycosylation transition states (13.8 and 25.5 kcal mol
for the wild-type protein and its mutant,
respectively). For the mutated protein, glycosylation led to a
low-energy product. This thermodynamic sink may correspond to the
intermediate state which was isolated in the X-ray crystal structure.
Hence, the glycosylation is validated to be the rate-limiting step in
both the wild-type and mutated enzyme. The E217Q mutation led to a
higher glycosylation activation free energy that also agrees with
experimental observation that mutation of E217 will slow down the
reaction, but not deactivate catalysis.
Del-Nido Cardioplegia in cardiac surgery for elderly patients: a propensity score-matched analysis
Authors: Gu Wenda , Qing Hongkun , Luo Xiang , Zang Xin , Zhou Kan , Guo Haijiang , Zhou Chengbin , Guo Huiming , Liu Jian
Published: December 2021

OBJECTIVES To compare the safety and efficacy of del-Nido
cardioplegia (DNC) with traditional 4:1 cold blood cardioplegia (CBC) in
coronary artery bypass grafting and/or valve surgeries in elderly
patients. METHODS The present study is a retrospective
case-series study that included 302 consecutive patients aged 70 years
and over who underwent on-pump valve surgery and/or CABG. DNC was
administered to 90 patients and CBC to 212 patients. After
propensity-score matching, 89 pairs were compared. The safety and
efficacy were analysed between the two groups. RESULTS Compared
with the CBC group (2185.8±582.9ml, P<0.001), the
volume of infused cardioplegia was less in the DNC group
(1423.6±259.5ml). The DNC group had a lower incidence of postoperative
intra-aortic balloon pump (IABP) implantation (1.1% vs 9.0%, RR=0.791,
P=0.034) and higher left ventricular ejection fraction (LVEF) at
discharge (58.5±9.1% vs 55.7±8.6%, P=0.007). The estimated
glomerular filtration rate (eGFR) in the DNC group was higher when the
patient was transferred to the intensive care unit (78.2±25.1
ml/min/1.73m vs 69.7±20.2 ml/min/1.73m
, P=0.021), but no significant differences
were identified after 24 hours. The serum lactate values of the DNC
group were significantly lower than those of the CBC group (0hrs:
2.8±1.5 vs 3.6±2.0, P=0.001; 3hrs: 3.6±2.7 vs 4.9±2.6,
P<0.001; 6hrs: 4.0±3.0 vs 6.1±3.3,
P<0.001; 9hrs: 4.4±3.3 vs 5.9±3.6, P=0.004).
There were no differences between the two groups in respect of lactate
levels at 12 hours and thereafter. Postoperative creatinine kinase-MB
concentrations were similar between the two groups. CONCLUSIONS
Del-Nido cardioplegia is safe and effective in elderly patients
undergoing CABG and/or valve surgery.
The Effect of Gender on the Relationship between Critical Thinking and Pattern Recognition: Students’ Perspectives
Authors: Ling Meng Kay Daniel , Loh Sau Cheong
Published: December 2021

In this qualitative study, individual interviews were conducted on 11 private school students to seek their opinions about the effect of gender on the relationship between critical thinking and cognitive pattern recognition. The participants, age 16 to 19 inclusive with six males and five females, were students recruited from three private schools in Singapore. All the interviewees have enrolled in the General Certificate of Education (GCE) 'O' level preparatory courses. The interview transcripts were analyzed using Qualitative Data Analysis (QDA) Miner software. The majority (64%) of the interviewees agreed that gender influence the relationship between critical thinking and pattern recognition. Two primary themes were identified that affect the effect of gender: the internal character traits of a person and society's influences. Two recommendations were to examine the impact of various internal character traits in more detail and to include interviews from school teachers and administrators to obtain more professional insights.
Argentinean Indigenous Culture in Animal Folktales
Authors: INES PALLEIRO MARIA
Published: December 2021

Bağımsız bir ulus olarak Arjantin'in tarihi, 1816'da başlatılmaktaysa da İspanyol
fatihler tarafından kuruluşu XVI. Yüzyıla kadar uzanır. Dünyanın en güneyinde
yer alan bu çok kültürlü Latin Amerika ulusu, ilk kez Hispanik fethi ile gelen
Avrupa kültürel mirası ile eski yerel yerli köklerin birleştiği bir ülkedir.
Arjantin'in başkenti Buenos Aires'in ilk kuruluşu, İspanyol fatih Pedro de
Mendoza Arjantin tarafından 1536 yılında gerçekleşti. Bununla birlikte, yerli halk
eski çağlardan beri Arjantin topraklarında yaşamaktaydı. İspanyol fatihler ülkeye
yerleştiğinde, 1813'te özgürlüklerini elde eden Afrikalı köleleri de satın aldılar.
XIX. yüzyılın sonlarından bu yana Arjantin, başta İspanya ve İtalya'dan, ayrıca
Asya ve Afrika ve Avrupa’dan ve diğer Güney Amerika ülkelerinden yeni göç
dalgaları aldı. Tüm bu kültür karışımı, halk anlatı metinlerinde ve
koleksiyonlarında yansıtılan Arjantin'in çok ırklı bir profilinin izini sürmeye
katkıda bulunuştur.Arjantin halk anlatısı içindeki hayvan masalları, yerli ve
Avrupa kültürlerinin karışımını yansıttıkları için son derece ilginç veriler
yansıtmaktadır. Makalede bu anlatılardaki karma kültürel yapı, metin analiz
yöntemleriyle saptanmıştır. Birçok hayvan hikâyesi, bu farklı
folklor türlerinin bir karışımını, kurgusal yaratıkların inanç söyleminin sınırlarını
aştığı çok sesli bir mesajda kendini gösterir. Perilerin görülmediği Arjantin halk
masallarında, hayvan masalları,olağanüstü masallar ve efsane gibi inanç anlatıları
arasında bir iç içe geçme söz konusudur. Bu çalışmada, Arjantin’in ana halk
anlatıları koleksiyonunda, Vidal de Battini (1980-1995) tarafından yazılan
Cuentos y Leyendas populares de la Argentina’da (Arjantin Halk Masal ve
Efsaneleri) İspanyol kültürüne ait bir masal olarak sunulan bir halk anlatı
ürününün bir versiyonunu analiz edeceğim.Omawaka deresinin kuzeybatı
bölgesinde kayıtlı, yerli Omawaka kültürüne ait “Hayvanların ilki tilki” adlı halk
masalı ile metinlerarası ilişkide yeni bir anlam kazanan mirası ortaya koymaya
çalıştım. Amaç, bu metinlerarası karşılaştırma yoluyla, bir Güney Amerika
ulusunun kültürel kimliğinin inşasında yerli kültür işlevlerinin altını çizmektir.
Arjantin hayvan masallarının farklı versiyonlarına yönelik bu karşılaştırmalı
yaklaşım, halk anlatı matrislerinin, yerel dünya görüşlerini yansıtan inanç
anlatılarıyla ilgilenen bağlamsal dönüşümlere karşı geçirgenliğini ortaya çıkardı.
Bu anlatıların ayırt edici özellikleri, insan eylemlerinin doğal ekosisteme verdiği
zarara karşı ciddi bir uyarıdır.
COVID-19 and Social Protection in Asia and the Pacific: Projected Costs for 2020–2030
Authors: Van der Auwera Michiel , van de Meerendonk Arthur , Ramesh Kumar Anand
Published: December 2021

Against the backdrop of the COVID-19 pandemic, this working paper applies a new costing model to analyze the costs associated with social protection in 30 Asia and Pacific countries. Using the Social Protection Reform Simulation (SPRS20) model, the authors seek to estimate the cost of delivering standardized social protection packages through the emergency (2020), recovery/transition (2021–2023), and the remaining duration for achieving the Sustainable Development Goals (2024–2030). This paper anticipates further demand and need for social protection for considerably large sections of the population. It aims to foster further research and discussion on social protection in Asia and the Pacific and aid countries in strategizing for the future.
Livedoid Pattern in the Abdomen of a Patient with Myelofibrosis: A Quiz
Authors: Soto-García Diego , Peón Gonzalo , Álvarez Carlos , Couselo-Rodríguez Carmen , Flórez Ángelez
Published: December 2021

Abstract is missing (Quiz)
19th Congress of the European Society for Dermatology and Psychiatry (ESDaP) and 2nd Brain Skin Colloquium Conference (BSC), June 11–13, 2021, London
Authors: Bewley Anthony , Barlow Richard , Ahmed Alia , Mohandas Padma
Published: December 2021

The Congress of the European Society for Dermatology and Psychiatry (ESDaP), held in conjunction with the 2nd Brain Skin Colloquium (BSC) Conference, hosted over 60 speakers delivering 47 oral presentations, 41 poster presentations and 5 keynote talks via 2 simultaneous livestream platforms. The 2-day conference, held biennially, was due to be hosted in London, but was converted to a virtual format due to the Covid-19 pandemic. This report presents a synopsis of the conference.
POLITICAL BOUNDARIES AND TERRITORIAL IDENTITY IN EARLY MODERN CENTRAL EUROPE: THE WESTERN FRONTIER OF TRANSYLVANIA DURING THE SIXTEENTH CENTURY
Authors: ARDELEAN Florin Nicolae
Published: December 2021

The last decades have witnessed an increased interest in the research of territorial delimitations in late medieval and early modern Europe. A significant part of the academic debate has been focused on identifying and defining the process of transition from medieval frontiers, perceived as vague areas of contact, to modern linear borders. The aim of this article is to analyse the organization of the western confines of the Transylvanian Principality during the decades in which this state was formed, from the Ottoman conquest of Buda (1541) until the ratification of the Speyer Peace Treaty (1571). Throughout this period, the territorial delimitation of Transylvania from the Ottoman Empire and Habsburg Hungary was an ongoing process, marked by both military confrontations and diplomatic negotiations. Through a critical reassessment of the most relevant Romanian and Hungarian literature on this complex subject and the analysis of new data from official and narrative contemporary sources, I have tried to identify which were the most important political and military events that shaped the western borderlands of Transylvania. A fundamental objective of my research is to provide an accurate definition for the western region of the Transylvanian Principality, contributing thus to the general debate on the nature of frontiers/borders in sixteenth century Europe.
Desarrollo de prototipo de un sistema de reconocimiento visual para determinar el grado de madurez de la de mauritia flexuosa en el departamento del Guaviare
Authors: Acosta Rodríguez Gustavo Adolfo , Hernández González Jesús Manuel , Figueroa Edgar Camilo , Salamanca Mahecha Daniel
Published: December 2021

Realizar un prototipo de un Sistema de Reconocimiento Visual (SRV) que por medio de  redes neuronales (inteligencia artificial) con acoplación de la caracterización del objeto a evaluar tendrá como funcionalidad la identificación de la madurez del fruto de la palma de moriche (Mauritia flexuosa) por medio de una imagen utilizando drones para los registros fotográficos de los racimos de la misma. Esto con el fin, primero, de minimizar la intervención humana en los humedales que son hábitats naturales de la palma para mantener el equilibrio en la fauna y flora propio de este ecosistema. Segundo, crear una alternativa económica legal y justa para las familias campesinas y comunidades indígenas del Municipio de San José del Guaviare.
Herramientas de ingeniería para el desarrollo de un software matemático
Authors: Hernández Molina Oscar Julián , Buitrago Tabares Bairo , Caamaño Cadavid Valeria
Published: December 2021

En este Working Paper se explicará la manera como se implementaron las herramientas de la ingeniería del software con el desarrollo del software matemático, haciendo que este sistema sea lo suficientemente competente para ser implementado en la Institución Educativa Nuestra Señora del Carmen, cumpliendo los estándares de calidad apropiados y basados en las mallas curriculares del grado 5° de primaria del Ministerio de Educación Nacional.

Este sistema fue desarrollado con el fin de que los alumnos aprenda de una forma didáctica y práctica cada uno de los temas y resuelvan los ejercicios para el grado 5° de primaria, permitiendo realizar una medición de los datos de los estudiantes, la utilización de las TICs como herramientas de software y la trazabilidad  mirando si con el sistema se logra la mejora continua con los alumnos.
La importancia de promover actividades de interacción en la producción lingüística de los aprendices del programa virtual English dot Works
Authors: Osorio Vélez Martha Isabel
Published: December 2021

El propósito de este estudio fue conocer hasta qué punto las diferentes actividades interactivas realizadas en las tutorías sincrónicas generaron un impacto en el desarrollo de habilidades comunicativas elementales en los aprendices del segundo nivel del programa English Dot Works (EDW) del SENA. Siempre reconociendo un enfoque de aprendizaje combinado y basado en las tecnologías de información y comunicación.  El estudio se realizó bajo una investigación cualitativa desarrollando un enfoque descriptivo cuasi experimental con un diagnóstico inicial, el cual dio cuenta del bajo nivel de los aprendices en la producci

El propósito de este estudio fue conocer hasta qué punto las diferentes actividades interactivas realizadas en las tutorías sincrónicas generaron un impacto en el desarrollo de habilidades comunicativas elementales en los aprendices del segundo nivel del programa English Dot Works (EDW) del SENA. Siempre reconociendo un enfoque de aprendizaje combinado y basado en las tecnologías de información y comunicación.  El estudio se realizó bajo una investigación cualitativa desarrollando un enfoque descriptivo cuasi experimental con un diagnóstico inicial, el cual dio cuenta del bajo nivel de los aprendices en la producción del idioma inglés como lengua extranjera (EFL) debido a la falta de estrategias de interacción en el curso en línea siendo un obstáculo para alcanzar las metas esperadas del nivel. Se realizó una etapa de acción de tutorías adicionales en las que se implementó y evaluó la propuesta del desarrollo y producción del lenguaje en entornos de aprendizaje en línea. El objetivo principal de la intervención fue ayudar a los aprendices a comprender mejor las nociones y los temas que se estudian en el curso; así como la producción lingüística por medio de actividades que promuevan interacción entre aprendiz-tutor y aprendiz-aprendiz.

ón del idioma inglés como lengua extranjera (EFL) debido a la falta de estrategias de interacción en el curso en línea siendo un obstáculo para alcanzar las metas esperadas del nivel. Se realizó una etapa de acción de tutorías adicionales en las que se implementó y evaluó la propuesta del desarrollo y producción del lenguaje en entornos de aprendizaje en línea. El objetivo principal de la intervención fue ayudar a los aprendices a comprender mejor las nociones y los temas que se estudian en el curso; así como la producción lingüística por medio de actividades que promuevan interacción entre aprendiz-tutor y aprendiz-aprendiz.
Producción orgánica de hortalizas bajo atmósferas controladas utilizando tecnologías de bajo costo
Authors: Valencia Francisco Javier , Carvajal Velásquez Juan Alejandro , Ruiz Salazar John Jairo
Published: December 2021

Históricamente, la agricultura ha experimentado una serie de revoluciones que han incrementado la eficiencia, el rendimiento y la rentabilidad a niveles antes inalcanzables. Los pronósticos sobre los mercados para el próximo decenio sugieren que una “revolución agrícola digital” será el cambio más novedoso que podría ayudar a conseguir que la agricultura satisfaga las necesidades de la población mundial en el futuro. (La, Las, & Rurales, 2019,P 1).La adopción de la agricultura 4.0 en el departamento del Quindío es baja, lo cual lleva a desarrollar modelos de producción poco eficientes y rentables; el propósito de este proyecto es la producción orgánica de hortalizas bajo atmosferas controladas, haciendo uso de sensores de medición a bajo costo (humedad relativa, temperatura, humedad del suelo), con el fin de validar su funcionalidad.
Storytelling y animación digital: usando cortos animados para la divulgación histórica y patrimonio cultural de la ciudad de Popayán
Authors: Muñoz Velasco Alan Fernando , Tumbo Ruiz Jhonatan Issac , Lemos Zuluaga Jonatan
Published: December 2021

El Storytelling o narración de cuentos o hechos ha evolucionado desde la mera narración oral hasta productos audiovisuales sofisticados que emplean tecnologías para el desarrollo de videojuegos, en este caso se emplea el software unity como base de soporte para el contenido animado. En el presente artículo se muestra la creación de un corto animado con enfoque a la divulgación historia de Popayán Cauca; la necesidad surge de promover la identidad cultural, salvaguardar el patrimonio material e inmaterial de la región alineado el turismo de experiencia-histórica. En ese sentido la animación digital es empleada para la reconstrucción digital y como medio didáctico para alcanzar el público a través de plataformas digitales y funcionar como herramienta de enseñanza. Por otro lado, es importante mostrar el flujo de trabajo de una producción digital de este alcance, que traspasa los aspectos técnicos e incluye investigación histórica, proceso de preproducción, producción y posproducción.
La narrativa transmedia: una revisión en su modalidad de webdoc como forma de fortalecer la identidad cultural en las provincias
Authors: Rodríguez Lezaca Adriana
Published: December 2021

En esta nueva era los desarrollos tecnológicos y las costumbres de consumo se han vuelto más exigente a nivel de comunicación, lo que ha dado origen a la Narrativa Transmedia; la cual permite mejorar las experiencias de usuario siempre y cuando exista la interacción que enriquezca la calidad de vida de sus habitantes y turistas.
Este artículo de revisión tiene como finalidad establecer los principales rasgos que se requieren para el desarrollo de un documental interactivo transmedia. Donde la narrativa es la base para el fortalecimiento de la Identidad Cultural, para así lograr aplicarlo en una provincia cuyo mayor recurso es el turismo.El proceso investigativo se centró en el análisis realizado por autores durante los últimos 10 años, contemplando también a aquellos que han dado fuerza conceptual a la Narrativa Transmedia o Storytelling. Siendo esta la finalidad de este estudio, al centrarse en la cultura convergente como elemento dimensional de la metodología transmedia, donde convive lo analógico con lo digital y cuya base es contar con unanarrativa audiovisual que permitan, generar y moldear en la conciencia social, al implementar la concepción del Webdoc o documental interactivo, el cual representa la realidad en un medio participativo y no recurre a la linealidad como elemento para contar la historia, requisitos que lo convierten en un formato nativo dela transmedia. A su vez, el documental interactivo requiere de un objetivo con carácter social por lo que la Identidad Cultural es una finalidad que corresponde a la aceptación y arraigo de un territorio fortalecido a través de una narrativa como atributo humano con un componente de realidad interpretada por la filmaciónde hechos que puedan llegar de manera digital, de forma masiva y colaborativa.
Experiencias de enseñanza, aprendizaje y formación
Authors: Allliaud Andrea
Published: December 2021

Este trabajo aborda dos textos autobiográficos: Ser escritor (2020) del narrador argentino Alberto Castillo y Mientras escribo (2016) del novelista americano Sthephen King, para analizar y comparar los motivos y los métodos que utilizan en su proceso de creación. Estos libros testimoniales son dos autobiografías y poéticas personales o manuales de escritura, que pueden considerarse textos de formación literaria. En ambos estos narradores cuentan sus vidas, explican de qué se trata su relación con la literatura y reflexionan sobre sus experiencias formativas, el proceso de la creación y cuáles son sus claves personales para producir una obra significativa. Los textos fueron escritor con el interés de compartir con los lectores los secretos de sus vidas y sus libros, es decir, con el objeto de enseñarles de qué se trata escribir. En este artículo presenta esta tentativa auto-referencial como una posibilidad metodológica propiciar de manera “no académica” el proceso de enseñanza-aprendizaje. Dado que producir relatos testimoniales y genuinos basados en la propia experiencia es una forma de establecer hoy en día una relación de identidad y empatía con aquellos individuos que están en situación de aprender.
Undercommunicated Stories in Boundary Building Processes
Authors: Uherek Zdenek
Published: December 2021

This text focuses on the narrations of Romani in the Czech Republic with regard to conversational topics which are usually not communicated in either conversations across group borders or in the media. The topics covered in these conversations range from everyday life issues and stories about success in employment to stories about experiences during powerful moments in the state’s history that resonate for all its inhabitants. The narratives analysed in this text include the experience of the invasion of Czechoslovakia in 1968 and the adventures of a group of boys who tried to illegally cross the state border during socialism. The interviews were filmed with a camera. From a methodological perspective, an interesting feature throughout the project was that during the conversations the narrators did not stress their Romani identity. The dominant tone was rather that of plain interpersonal communication. Thus, these narratives can be characterised as acts of everyday communication – a mode of interaction which is not common in the communication of Roma with non-Roma – which emphasize the shared overall context in which all inhabitants of the Czech Republic find themselves.
Long-Term “Ethnicized Silences”, Family Secrets and Nation-Building
Authors: Soler Elena
Published: December 2021

This article demonstrates the dynamic relationship between long-term ethnicized silences, family secrets and nation-building in Central and Eastern Europe. How have modern nation-states been imagined and formed on the basis of these long-term silences? In order to illustrate what we believe could be the contribution to anthropology (principally to nationalism studies) enabled by introducing this analytical category of silences, in this research we will focus on a close analysis of the life story and identity journey of a self-identified “Slovak woman with Hungarian-Roma roots” who settled in the Czech Republic in 2009. Through this ethnographic example, and in an attempt to go beyond particularities, some of the themes covered are: what meanings, uses and processes of silences can we find in Slovakia, and what is their relationship to the construction of minorities and to an ethno-cultural model of nation-building (an imagined community)? In which domains and under which power relationships have long-term silences and hidden family secrets prevailed in everyday life? To what extent have those silence frameworks been negotiated and used as intergenerational strategies of family unity and protection? And finally, within the context of migration and the complex processes of Europeanization and globalization, how have those long-term, in this case “shamed”, ethnicized Roma silences been contested and broken, and what is the meaning of this development (at micro and macro levels)? In other words, for nation-states that have long been imagined on the principle of ethno-cultural homogeneity, I ask what can long-term ethnicized silences tell us about the process of nation-building (from the bottom up) and the quality of our EU democracies? Where do we come from, where are we now and, at least in terms of a warning (due to the rise of xenophobic forms of populism and radical nationalism), where are we going?
INNOVATIVE APPROACHES TO THE FORMATION OF “SOFT SKILLS” IN THE PROFESSIONAL ACTIVITY OF SERVICE PROFESSIONALS
Authors: Shestel Olena , Starynets Olena , Danyliuk Alla
Published: December 2021

The article analyzes the role of and approaches to the formation of “soft skills” in the studying and professional activities of service professionals.

The relevance of the proposed study lies in the lack of coverage in the scientific literature of the role of “soft skills”in the professional activities of service professionals. It should be noted that the role of “soft skills” in the process of performing professional tasks of specialists in various fields of knowledge is increasingly attracting the attention of scientists, primarily due to globalization, focus on European quality standards in services, and employers' requirements for employee’s not only professional but also social skills.

To achieve this goal it is necessary to perform the following tasks: to determine the pedagogical conditions for the formation of “soft” competencies in higher education in Tourism and Hospitality, which are extremely important for the daily professional activities of hospitality professionals, to analyze the prospects for “soft skills” actually in the process of professional activity, during professional internships, etc., as well as to analyze the current requirements of employers to the level of mastery of social skills.

Achieving this goal led to the use of the following research methods: systematization of modern scientific literature, theoretical analysis of scientific sources to determine the status and theoretical justification of the role of “soft skills” in the professional activities of service professionals. Methods of empirical research: observation, comparison, generalization.

It was proved that social skills play an important role in the professional activities of hospitality professionals, as the implementation of daily tasks is related to communication, including communication in foreign languages, teamwork, cooperation, stress, responsibility, etc. It should be noted that the analysis of labor market requirements revealed that employers are increasingly paying attention to the possession of future employees’ not only professional knowledge, skills and abilities, but “soft”competencies.
MODERN FORMS OF ORGANIZATION AND PROCESS OF ANIMATION SERVICE AT HOTEL ENTERPRISES
Authors: Tymchuk Svitlana , Tereshchuk Natalia
Published: December 2021

The article considers the process of improving the quality of service in hospitality enterprises through animation activities. Animation is considered as a whole industry in hotel service, an integral part of the whole service and quality hotel service. The paper also outlines areas for improving service in hotel enterprises through the introduction of animation services to their activities.

The main purpose of this article is to analyze the factors influencing the development of animation services, to reveal the main functions and directions of animation services and to find possible innovations in the hotel industry animation programs, using the experience of leading hotel companies and foreign countries.

The problem of product quality assurance is very important now, because much in the development of a particular industry depends on how progressive its implementation is. However, speaking about the main indicators of quality, as well as possible problems that may arise with the release of quality services, they are individual for the hotel and restaurant business and the hospitality industry in general. Now a whole new direction has been actively used all over the world - animation, it occupies an important niche in the development of tourism in general, and is quite relevant for the effective functioning of hospitality enterprises. The organization of animation is the main part of the hotel business, which expresses its high degree of professionalism.

Considering the animation service in hotels, we can conclude that in today's world in conditions of fierce competition in the market of tourist services it is impossible to imagine a hotel complex without the organization of animation activities. In order for the guests of the hotel and restaurant business of different nationalities, different ages, wealth and opportunities (physical, intellectual, etc.) to remain satisfied, animation programs must be improved and changed throughout the season in content, intensity, time and other parameters for the return of visitors to the hotel.
Kemampuan Dosen dalam Membuat Soal HOTS Pada Pembelajaran Abad 21
Authors: Ali Ahmad , Arif Wiwin Pramita , Ichsan Ilmi Zajuli , Sigit Diana Vivanti , Darussyamsu Rahmawati , Dasmo Dasmo , Nurfadhilah Nurfadhilah , Fachrial Nur Fadli Hazhar
Published: December 2021

Twenty-first century learning requires high-level thinking skills including critical thinking, communication, collaboration, and creativity known as the 4Cs. The purpose of this study was to determine the ability of the lecturers of the Biology Education Study Program at UIN Alauddin Makassar in making Higher Order Thinking Skills (HOTS) questions and to find out the responses of the lecturers of the Biology Education Study Program at UIN Alauddin Makassar on the importance of developing HOTS questions. This research is a quantitative descriptive research. This research was carried out in the odd semester of the 2019/2020 Academic Year with the research subjects of all lecturers of the Biology Education Study Program at UIN Alauddin Makassar who have educational backgrounds according to the study program as many as 12 people. Data collection techniques through question documentation and questionnaires. Data were analyzed by descriptive statistics. The results showed that Lecturers of the Biology Education Study Program were able to make higher order thinking questions (HOTS) with a percentage of 33% Very Able, 8% Able, and 17% Enough, while the remaining 42% with the criteria of Poor. As many as 85% of the Lecturers of the Biology Education Study Program at UIN Alauddin Makassar gave a positive response to 74% of items stating the importance of making higher order thinking questions (HOTS). Suggestions from this study was that Biology Education lecturers can innovate HOTS-based educational evaluations.
Pengembangan Media Interaktif Mata Kuliah Teknik Analisis Biologi Molekuler (TABM)
Authors: Lestari Fitria
Published: December 2021

Molecular Biology Analisis Techniques (TABM) is one of the courses that discusses the basic techniques needed for molecular biology. Learning in TABM, is more emphasis on procedural, so the process by using books alone is not enough. Therefore, to support the TABM learning process, interactive were developed consisting of text, sound, images, and research videos. This type of research is R & D is a research and development design by modifying the systematics of Kemp and Dayton. The development steps are to determine the specific learning objectives of the product; prepare material and video content; creating storyboard, developing, editing, and mxing; testing and revising. The instruments used are validation sheets and questionnaires for students with qualitative and quantitative data analysis techniques. Based on the result, there are several suggestions and inputs including: design, instructions for use, product packaging, introduction of tools and initial materials, and procedures. While quantitatively it can be seen that the developed interactive media doesn’t need to be revised and is suitable for use, namely 92,1% of field experts and 70,2% of media experts. It can be concluded that the development of interactive media can be used ini procedural courses such as molecular biological analysis techniques.
Analisis Kebutuhan Pengembangan E-Modul Bermuatan Video Pembelajaran pada Pendidikan Jarak Jauh bagi Calon Guru Fisika
Authors: Anggreini Anggreini , Permadi Dimas
Published: December 2021

Distance Education (PJJ) as a learning solution during the COVID-19 pandemic at the University of Lampung has not been implemented optimally. The purpose of this study was to find out the circumstances and needs of prospective physics teacher students while carrying out PJJ online from their respective homes. As well as analyzing the materials and assignments to achieve the Subject Learning Outcomes (CPMK) of Educational Research Statistics. This study uses a descriptive analysis method with a research instrument in the form of a questionnaire distributed online with the help of a google form. The sample in this study was 53 students of physics teacher candidates in the Physics Education Study Program, University of Lampung. The results of this study indicate that the condition of students in implementing PJJ is that they already have adequate facilities both from electricity infrastructure, internet networks, devices, and getting support from family. However, students find it difficult to understand practical learning when using media and learning methods that are not varied. The analysis of materials and tasks developed from CPMK Educational Research Statistics consists of three main materials with ten learning videos, and each student is asked to complete matters an educational research case using SPSS. Based on the results of this needs analysis, lecturers need to develop a teaching material, namely an e-module containing learning videos that can facilitate prospective physics teacher students in implementing PJJ.
Pengembangan Butir Soal Literasi Kimia pada Materi Sistem Koloid Kelas XI IPA SMA/MA
Authors: Eliza Wirna , Yusmaita Eka
Published: December 2021

This study aims to develop a chemical literacy instrument on colloidal system material that can be used to measure the literacy level of students. The research design on the development of this chemical literacy instrument uses the Model of Educational Reconstruction (MER). This research has several stages including content structure analysis (curriculum analysis, content analysis, context analysis, content validity by subject matter experts) and teaching and learning research (student interview investigation). The content validity test is carried out by five validators and the results will be analyzed by the Rasch model using the facet application. The results of this study indicate that the value of exact agreements is 88.9%, while the value of the expected agreements is 89.6% so it can be said that the results of the examiner's assessment are not much different from the expected results of the assessment
Forensic characteristics of fissures as valuable morphological signs to detect mechanogenesis of fractures of long bones in the lower limbs
Authors: Savka Ivan
Published: December 2021

The objective of our work is to study regularities of formation and spread of cracks of long bone diaphysis in the lower limbs for more profound understanding of biomechanics of fractures. The material of the study was 128 cases with injuries of the femoral, tibia and fibula bones. The data obtained were statistically processed by means of multifactor analysis of variance (MANOVA). Different kinds of cracks were found to possess their own signs by the number and direction reflecting mechanics of fractures of the examined bones. The value of deviation angle of wedge-shaped cracks was found to be of a special diagnostic importance. Detected regularities can be used in forensic medicine practical work in case of retrospective renewal of conditions and circumstances of getting injuries.

Objective: to formulate new regularities in the process of formation and spread of diaphysis cracks of long tubular bones in the lower limbs for more comprehensive understanding of biomechanics of their fractures.

Materials and methods. The material of the study was based on the expert investigations including 82 persons with 128 injuries of the lower limbs: femoral bones – 40 cases, tibia – 46 cases, fibula – 42 cases. The data obtained were statistically processed by means of multifactor analysis of variance (MANOVA).

Conclusions:

Different kinds of cracks have their own signs by the number and direction reflecting mechanics of fracture of certain portions in the long tubular bones of the

lower limb.

Cracks in the rupture area are of more importance to detect the mechanism of The value of deviation angle of wedge- shaped cracks is of a special diagnostic importance.

Prospects of further studies. Prospects of further studies assume computed multi-dimensional visualization of crack characteristics of different bones of the human skeleton.
The comparative analysis of suicides in Plovdiv oblast (Bulgaria) and in Khmelnytskyi oblast (Ukraine) and social and economic problems of suicides
Authors: Baltov Maryn , Kozytska Nataliia , Havadza Roman
Published: December 2021

Suicide is an important social problem of modern society. Every year in the world from 800 000 to one million people commit suicide. Suicides occur every 40 seconds. Suicide is the 15th cause of death in the world. The committing of suicides by people is in close connection with the social and economic problems of society. With the intensification of integration processes and the weakening of social ties, a person feels lonely and unprotected in a social environment, he/she is unable to solve problems of a different nature and is under constant stress. The World Health Organization emphasizes the suicide problem and raises the issue of its solution.

The purpose of the study is to compare suicide cases in two countries, which, in our opinion, earlier developed similarly and had much in common, but they appeared on the path of democracy at different rates and methods; to analyze some social aspects of suicides and their correlation with economic indicators, such as gross domestic product (GDP) per capita and unemployment rate.

CONCLUSIONS

During the period from 2006 to 2015 in Khmelnytskyi oblast suicides were committed twice more than in t Plovdiv oblast.

The dynamics of suicides in the Plovdiv oblast is unstable, in its turn, in Khmelnytskyi oblast there is basically a similar number of cases.

When assessing suicides in age categories, a similar pattern is observed in the age groups from 0 to 18 years old and from 44 to 65 years old, with a difference in age groups of 19-43 years old with an increase in cases in Khmelnytskyi oblast and a group of over 65 years old with an increase in cases in Plovdiv In our opinion, this may be due to the economic development of the country, the young people’s inability to realize themselves and the different worldviews and difficulties in adapting to life for the elderly.

The same picture is observed in the study of suicides committed by men and Men both in Plovdiv oblast and in Khmelnytskyi oblast commit the majority of suicides. It can be concluded that men are more prone to suicide. In our opinion, this is due to the inability to support the family, due to the abuse of alcohol and drugs and due to the inability to overcome the existing obstacles.

There is a link between the level of economic development of the country and the rate of suicide deaths. The level of living in Bulgaria is twice higher (in terms of GDP) than in Ukraine and the mortality rate is twice lower.
Modern principles and methods of objects of biological origin in forensic immunology
Authors: Shevchuk Mykola , Demchuk Iuliia
Published: December 2021

Over time, the more important question is the preservation of biological material discovered in the wake of material evidence during the immunological expertise for the further application of molecular genetic research methods, which in turn increases the objectivity of evidence and forensic expert results. The article suggested directions, the steps and methods of modern immunology expertise.
Asphyxiation by inhaling the inert gas helium inside a plastic bag
Authors: Shilan Volodymyr , Shilan Cyril , Shalniev Oleksii
Published: December 2021

А case of death from asphyxiation by inhaling the inert gas helium inside a plastic bag placed over the head.

Findings and discussion. In our practice, we had a case of post-mortem examination of a 22 y.o. male. As it is known from the circumstances of the case, the mail corpse was found in a forest belt area, with his head inside a black plastic bag tight-fitted around his neck with a band. In the bag, there were two plastic tubes – one of them was placed obliquely at the level of right anterior surface of neck and was fixed to the neck with transparent adhesive tape. The other end of tube was connected to the outlet of a valve on a cylinder of brown color superscribed «HELIUM». The valve of a cylinder was opened. The other tube is located on the left side of the neck, with a rubber ball attached to the exposed end.

On post-mortem examination, we found the following: face – pale, not congested, w/o petechiation; livor mortis – generalized dark purple discoloration of the skin. Findings on internal examination: congestion of internal organs; dark-red liquid blood inside the cardiac cavity and larger vessels; hemicardiadextra, SVC and IVC overfilled with blood. No hemorrhages under epicardium and pleura.

Findings during microscopic examination of internal organs: Heart: lack of arterial blood, venous congestion. Albuminous degeneration of cardiomyocytes. Interstitial edema. Areas of dystelectasis, acute vesicular emphysema. Pulmonary congestion.

Liver: irregular blood filling of tissue. Albuminous degeneration, destruction of hepatocellular cytoplasm. Interstitial edema. Kidney: cortical ischemia, congestion of straight venules. Albuminous degeneration in nephrothelium of convoluted tubules. Interstitial edema. Brain: irregular blood filling of cerebral vessels. In pia mater: edema&focal infiltrates of fresh RBCs. Focal voids surrounding the vessels and neurons. Ischemic degeneration of neurons. Red blood cells accumulations in the enlarged paravasal spaces. Suprarenal gland: irregular venous congestion of tissue; occasional thinning of adrenal cortex. Pancreatic gland: lack of arterial blood, venous congestion. Spleen: irregular blood filling of tissue. Decision: morphological signs of acute death. Pulmonary edema. Forensic toxicology test results: methyl, ethyl, isopropyl, butyl, isoamyl alcohol; barbiturates; opium alkaloids – morphine, codeine and their synthetic analogues; phenothiazine, benzodiazepine derivatives; ephedrine, ephedrone – have not been identified.

Conclusion: As can be seen from the above, the results of forensic examination of corpse, forensic toxicology and forensic histology tests, with account being taken of circumstances and scene investigation details, allowed suggesting that the possible cause of death was the asphyxiation by inhaling the inert gas helium inside a plastic bag placed over the head.
The effect of ethyl alcohol on accuracy of time since death estimation using laser poliarimetric methods of cerebrospinal liquid polyristallic films investigation
Authors: Garazdiuk Marta , Bachynskyi Viktor , Lebedintseva Iryna , Garazdiuk Oleksandr , Andriichuk Andrii
Published: December 2021

The article analyzes the possibility of using laser polarimetry methods to determine the possible influence of ethyl alcohol in the body of the deceased on the change in the structure of the polycrystalline films of the cerebrospinal fluid. The efficiency of usage laser polarimetry methods (determination of complex degree of mutual polarization and autofluorescence of polycrystalline films of cerebrospinal fluid) have been proved.

Relationships between the distribution of the intensity of the fluorescence of polycrystalline films of the cerebrospinal fluid of the cadavers as a result of cardiovascular pathology in the presence and absence of ethyl alcohol in the organism and the values and ranges of the change of statistical moments of the 1st - 4th orders that characterize such autofluorescence images are investigated. A good level of balanced differentiation of the presence of ethyl alcohol in the human body in the «green-yellow» and «red» sections of the spectrum has been achieved. There is a statistically significant difference between cases of death from cardiovascular disease in the presence and absence of ethyl alcohol in an organism by determining the magnitude of the statistical moment of the 4th order, which characterizes the distributions of the azimuth magnitude of the polarization of microscopic images of laser-induced fluorescence.

On this basis, an excellent balanced accuracy of the differentiation of the presence of ethyl alcohol in the human body (Ac (M4) = 94%) has been achieved. Consequently, ethyl alcohol affects the structure of polycrystalline films of cerebrospinal fluid, which should be taken into account when time since death estimated using methods of laser polarimetry.
Acceptability and Willingness to Pay for Influenza Vaccination among Healthcare Professionals in Vietnam
Authors: Nguyen Trang Thi Thu , Kasemsup Vijj , Tiraphat Sariyamon , Srithamrongsawat Samrit , Chuakhamfoo Nalinee Nakittipha
Published: December 2021

Background: While Vietnam’s Expanded Program on Immunization does not cover influenza vaccines, people must pay out-of-pocket for influenza vaccination. Healthcare professionals have a high risk of contracting influenza, but their vaccination rate is low. 
Objective: To examine the willingness to pay (WTP) for influenza vaccination among healthcare professionals in Vietnam. It also recommends financing sources for influenza vaccination among healthcare professionals and determines possible measures to expand vaccine coverage.
Method: We interviewed 130 healthcare professionals in a national hospital in Hanoi in July 2021. We used Andersen’s behavioral Model (ABM) as an initial approach. The double-bounded dichotomous-choice questions were used to determine WTP for influenza vaccination among the target group. Collected responses were coded and analysed through IBM SPSS version 20 for descriptive, chi-square analyses. 
Results: Most of the healthcare professionals who responded to this study were female with 75.4 % of the total 130 respondents. The mean age of participants was 34.08 years old. The average maximum WTP for influenza vaccination services was 357.57 VND (USD 15.3). Most of the participants reported that individuals should pay a part of the cost, and four-fifths reported they believed that the government and medical insurance should subsidize the service (80.8 % and 85.4 %). The Chi-square test showed that there was a significant association between perceived severity and history of influenza vaccination with the WTP, X2(1, N=130) = 4.18, p = 0.04 and X2 (1, N=130) = 7.81, p = 0.005, respectively.
Conclusion: The WTP for influenza vaccination among healthcare professionals was found relatively high. Suggesting that price is not a primary barrier. The government and medical insurance were believed to be the potential agencies for improving vaccination uptake as these agencies were expected to be the subsidized actors. Other health interventions such as influenza literacy and communication methods are also needed to expand vaccine coverage.
(*The paper was presented at The Hong Kong Polytechnic University’s College of Professional and Continuing Education (CPCE) Conference “Post-pandemic health and long-term care: A new paradigm”. September 2021)