bluuebunny/crossref_metadata_2025 huggingface dataset:
Osteosarcoma’s genetic landscape painted by genes’ mutations
Authors: Urban Wiktoria , Krzystańska Dagmara , Piekarz Michał , Nazar Jerzy , Jankowska Anna
Published: September 2023

Purpose: Osteosarcoma (OS) is one of the most common primary bone tumors. Direct pathogenesis remains unknown, however, genes’ mutations are proven to participate in the process. This study aimed to examine the most frequently mutated genes in OS to appoint candidates for the cancer markers. Methods: Using the COSMIC Catalogue twenty the most frequently mutated genes were selected leading to an up-to-date genetic OS landscape summary. The genes can be classified into four categories: suppressor genes (TP53, RB1, NCOR1, SMAD2, NF1, TSC2, KMT2C), proto-oncogenes (GNAS, BRAF, MLLT3), epigenetic and post-translational modification-related genes (SMARCA4, ARID1A, ATRX, BCOR, H3F3A) and cell growth and survival regulating genes (EGFR, CAMTA1, LRP1B, PDE4DIP, MED12). Results and conclusions: Their role in cancerogenesis was confirmed by the analysis of available articles published previously. The results of the study indicate that examination of selected genes’ mutations might help to identify patients’ predisposition to OS development, as well as monitor the disease progression, and establish prognosis. However, to fully understand the pathogenesis of OS further studies are required.
Impact of diet modification on body mass and kidney function in patients with diabetic nephropathy: a pilot study
Authors: Kaczkan Małgorzata , Czaja-Stolc Sylwia , Sikorska-Wiśniewska Małgorzata , Chmielewski Michał , Dębska-Ślizień Alicja , Małgorzewicz Sylwia
Published: September 2023

Objectives: The increasing trend in chronic kidney disease (CKD) has occurred in parallel with the increased prevalence of obesity and diabetes type 2. The relationship between a reduction in body mass and protein intake in diabetic nephropathy (DN) has not been adequately understood. This study aimed to determine whether dietary intervention in an adult with DN is associated with decreasing proteinuria or changes in kidney function over six months. Methods: The study included 120 patients with DN, consecutively admitted to a dietitian from a Kidney Disease Clinic. Patients were classified into two groups: a reduction diet or a normal calorie diet, both with 0.8 g of protein/kg of ideal body weight/day. Anthropometric and laboratory assessments were done before and after observation. Results: After six months, in the study group of patients on a reducing diet, a decrease in body mass, body mass index (BMI) and stabilization of estimated glomerular filtration rate (eGFR) were observed. There was also a significant correlation between the time of diabetes diagnosis and eGFR and creatinine (R Spearman=–0.24 and 0.3, respectively; p=0.05). There were no other significant associations between body mass, BMI, albuminuria, eGFR, or creatinine. Conclusions: The study shows that obesity is a common comorbid disease in patients with DN and that dietary intervention is associated with a significant reduction in body mass and stabilization of eGFR in these patients.
Analytical method of optical wave behavior studying in nonlinear medium with periodically arranged conducting nanofilms
Authors:   Astrakhan State Technical University, Volkova Svetlana , Vytovtov Konstantin ,   V. A. Trapeznikov Institute of Control Sciences of the RAS, Barabanova Elizaveta ,   V. A. Trapeznikov Institute of Control Sciences of the RAS, Khakhomov Sergey ,   Francisk Skorina Gomel State University, Kovalenko Dmitry ,   Francisk Skorina Gomel State University, Ivanov Mihail ,   National Research University “Moscow Power Engineering Institute”
Published: September 2023

The purpose of this work is to build the analytical model of the behavior of a harmonic wave in a nonlinear optical medium with periodically arranged nanofilms. Methods. The modernized method is presented of non-smooth transformation of the argument to eliminate the Dirac functions on the right side of the non-linear inhomogeneous differential equation describing linear polarized wave behavior within a non-linear optical medium with periodically arranged conducting nanofilms. Small parameter methods, in particular, the averaging method, is also used to find an approximate analytical solution. Results. The fully analytical model of the behavior of a linear polarized harmonic wave within a nonlinear optical medium with periodically arranged conducting nanofilms is constructed. Conclusion. For the case of propagation of a linearly polarized harmonic wave in a nonlinear optical medium with periodically arranged conducting nanofilms, the mathematical model based on the non-smooth argument transformation method is constructed. The model is fully analytical, all expressions are obtained directly from Maxwell’s equations by identical transformations. The limits of its applicability are determined by the limits of application of the wave theory of light.
Tumor Necrosis Factor-α (-308G>A) Gene Polymorphism and Its Association with Asthma and Atopy Status
Authors: Razaghian Anahita , Parvaneh Nima , Amirzargar Ali Akbar , Gharagozlou Mohammad
Published: September 2023

Asthma is one of the most prevalent chronic lung diseases that afflict genetically predisposed individuals. Certain cytokine gene polymorphisms have been associated with asthma. Tumor necrosis factor-alpha (TNF-α) is a potent inflammatory cytokine that can modulate nonspecific inflammation to influence asthma. This study aimed to define the relationship between the TNF gene polymorphism at position -308 and asthma susceptibility, as well as atopic and nonatopic asthma.
Using polymerase chain reaction with sequence-specific primers, we investigated genotype frequencies and alleles of a polymorphic gene coding for TNF-α in 86 pediatric patients with asthma and 470 healthy controls of the same race. Seventy-four patients underwent a skin prick test.
The homozygous AA variant (-308, rs1800629) was the most common genotype among patients, accounting for 63.3% of all cases. In contrast, homozygous GG (-308) was significantly less prevalent in the patient group compared to the control group. TNF A (-308) allele frequency was 85.5% among asthma patients and 16.6% among healthy controls. The genotype and allele frequencies of TNF (-308 A>G, rs1800629) did not differ between atopic and nonatopic asthma.
In conclusion, TNF (-308) AA and AG genotypes are associated with asthma susceptibility in Iranian children, although there was no significant difference in polymorphism between atopic and nonatopic asthma and no difference in asthma severity groups.
Metagenomics Characterization of Ixodes ricinus Intestinal Microbiota as Major Vector of Tick-Borne Diseases in Domestic Animals
Authors: Yousefi-Behzadi Manijeh , Mehrabi Atefeh , Ahmadinezhad Mozhgan , Rohani Mahdi , Naddaf Saied Reza , Bagheri Amin , Shams-Ghahfarokhi Masoomeh , Maghsoudlou Ebrahim , Mojahed Nooshin , Mounesan Leila , Tahmasebi Zahra , Sohrabi Aria , Salehi-Vaziri Mostafa , Salehi Zahra , Razzaghi-Abyaneh Mehdi
Published: September 2023

Background: Understanding the microbiota of disease vectors can help for developing new strategies to prevent the transmis­sion of vector pathogens. Ixodes ricinus is one of the most notorious tick vectors with increasing importance in Iran and other parts of the world while there is limited data on its microbiota. This study aimed to use metagenomics for identifying the I. ricinus tick’s microbiota of Iran.
Methods: A total of 39 adult ticks were collected from Mazandaran (21 females), Gilan (17 females), and Golestan (1 male). Five tick pools prepared from 39 adults of I. ricinus were subjected to metagenomics analysis. The data were analyzed by targeting the V6 region of the 16S rRNA gene by Illumina 4000 Hiseq sequencing.
Results: Among hundreds of intestinal microbiota identified by metagenomics, various pathogenic microorganisms distributed in 30 genera and species including those responsible for tick-borne diseases resided in the genera Coxiella, Rickettsia, and Burkholderia were found.
Conclusion: Our results indicated that metagenomics identifies bacteria genera and species which cannot be easily rec­ognized by routine methods. The presence of such pathogenic bacteria indicates the importance of possible zoonotic diseases in this region which could affect public health. These results further substantiate the importance of advanced metagenomics analyses to identify neglected tick-borne pathogens which enable researchers to provide efficient map­ping roads for the management of emerging and re-emerging infectious diseases.
Decline of Malaria Incidence in Three Villages of Thar Desert, India: the Im-pact of Use of Insecticide-Treated Nets
Authors: Mohanty Suman Sundar , Kanojia Phool Chand
Published: September 2023

Background: Malaria is the most important tropical and parasitic disease in the world. Endophagy of many malaria vectors­­­­­­­­­­­ advocates that impeding their entry into houses and preventing their contact with the occupants from infective bites could protect them against malaria.
Methods: The study was carried out in Jaisalmer District, India and three villages were selected as test villages and three as control. Cross-sectional malaria prevalence surveys and mosquito collections were conducted in all the study villages. Insecticide-treated nets (ITNs) were tied below the beds for personal protection against the mosquito bite. Door and window curtains along with partition curtains were treated with insecticide for baring the entry of mosquito vectors.
Results: Plasmodium vivax and P. falciparum were reported from the study villages. Higher malaria cases were detect­ed in the control villages than the insecticide-treated bed net-distributed villages. The percentages of reduction of mos­quito density in the houses of the ITNs distributed villages were significantly higher than the control villages. The insec­ticide activity was decreased slowly, and the knockdown time (KD50) values were found to be increased with the dura­tion of usage of net. The KD50 of Anopheles subpictus s.l. was found to be more than the An. stephensi. Rooms where the ITNs were found to be significantly lower per man-hour density of mosquitoes.
Conclusion: The use of alternative forms of ITNs shows a potential for preventing malaria and are making a significant contribution to the mosquito control. Effective use of ITNs could be helpful in the malaria elimination in India by 2030.
L’importance de l’informatique et de la langue anglaise dans l’enseignement commercial
Authors: BULOBA ANDRE
Published: September 2023

L’informatique et la langue anglaise sont deux compétences importantes pour l’enseignement commercial. L’informatique est essentielle pour la gestion des données et l’analyse de l’information, qui sont des éléments clés de toute entreprise commerciale. Elle est également utile pour la communication et la collaboration en ligne, ainsi que pour la création de documents professionnels et de présentations.
Motion of energy
Authors: Trivedi Nripesh
Published: September 2023

In [1], it was given that the principle defining movement of energy is equilibrium. This paper describes a further notion or reason that defines movement of energy. In [2], it was stated that energy moves from a place of higher magnitude to a place of lower magnitude. This paper highlights a simple reason defining motion of energy by reasoning.
Certain conclusions on results of introducing the reliability design and technological analysisin rocket and space production. Part 1
Authors: Pokhabov Yu.P.
Published: September 2023

The paper summons typical errors of designers, their misconceptions and miscalculations (hereinafter referred to as the errors) in design and development of the rocket and space products, which were identified in analyzing design and technological documentation using a new method of reliability design and technological analysis. Analyzes were carried out in the mode of external examinations and testing by designers of their proprietary developments. Errors identified during the analysis are typical for the modern quality control systems with the normative and technical documentation in force in the rocket and space industry to ensure quality and reliability. Taking into account even those errors indicated in the paper could significantly increase efficiency of the design work and reduce the number of failures in the rocket and space products. However, they are far from exhaustive. Identifying the most complete list of errors in design and technological documentation requires the mandatory reliability design and technological analysis in development of new and modified products.
Concept formation of a satellite constellation for early detection of the forest fires
Authors: Poluektov R.M. , Reutova S.V.
Published: September 2023

The paper considers concept formation of a satellite constellation for early detection of fires in Siberia. Within the framework of the stated concept, an orbit was selected for deployment of a satellite constellation, and the flight path of satellites in a circular sun-synchronous orbit was constructed. The CubeSat platform is proposed as the basis for potentially applicable spacecraft for remote sensing of the Earth, the satellite expected appearance was created in the form of a 3D model, and the principle of satellites’ operation is described. It is assumed that the satellite would only take images and transmit them to the ground control station. To analyze images received from the satellites, the software is proposed that automatically detects fires and implements an algorithm using the OpenCV computer vision algorithm library. As a means of launching the satellite constellation, it is proposed to use the light-class Angara-1.2 launch vehicle.
Noble estate of Vits-Grigoryevs (Kostroma region): history of creation and current state
Authors:   Russian State Agrarian University — Moscow Timiryazev Agricultural Academy, Lebedev A.V. ,   State Nature Reserve «Kologrivsky Forest» named after M.G. Sinitsyn, Kochnev Ya.V. ,   State Nature Reserve «Kologrivsky Forest» named after M.G. Sinitsyn
Published: September 2023

Provincial noble estates are an important component of the domestic architectural and landscape heritage. Over the years, there has been a loss of significance of noble estates as a phenomenon of Russian national culture. Therefore, the role of noble estate and park complexes as cultural landscapes and as elements of preserving the cultural identity of Russia is increasing. This issue is of particular relevance for the Kostroma region, where there is an extremely low safety of rural noble estates. The aim of the study was to examine the history of the creation of the noble estate of the Vits-Grigorievs and the current state of its natural and anthropogenic landscapes (Kologrivsky district of the Kostroma region). The research was carried out in several stages using the following methods: historical and archival expertise, field surveys, graphic-analytical method. By 1917, the manor complex included the main house with outbuildings, garden and park and utility parts, an orphanage with a school. To date, none of the manor buildings have survived. The basis of the complex is a larch-linden park, formed in two stages: in the first half and in the last quarter of the 19th century. An assessment of the sanitary condition of plantings and the structure of the tree canopy made it possible to conclude that an active process of decay of park plantings is taking place. To date, there has been an almost complete displacement of ornamental plants on the estate by species from wild flora. Since 1917, musk strawberry (Fragaria moschata), germander meadowsweet (Spiraea chamaedryfolia), Siberian peashrub (Caragana arborescens) and common lilac (Syringa vulgaris) have remained in the assortment of ornamental plants. To preserve the historical and cultural value of the object, it is necessary to carry out measures for its reconstruction. Modern use of the territory may include the creation and implementation of a tourist route.
Research development by generation of electromagnetic radiation under adhesion contact breach (review)
Authors:   State Fire Academy of EMERCOIM of Russia, Evdokimov Yu.M. , Figovskiy O.L. ,   Israeli Inventors Association
Published: September 2023

The emergence of a wide range of electromagnetic radiation at failure of adhesive contact (visible, radio, IR, UV, X-ray and acoustic) is investigated. The results of research works obtained by employees of The Academician B.V. Deryagin scientific school, including his own, are presented. New results on assessment of adhesive bond strength for film-substrate systems are presented, as it became possible to judge the strength of adhesive bonds by electromagnetic radiation characteristics (period, amplitude, frequency, etc.) and not only by «mechanical» approaches.
Styl atrybucji, poczucie kontroli i płeć a podatność na powstawanie syndromu wyuczonej bezradności
Authors: Jarmakowski Tomasz
Published: September 2023

The article is the review of chosen researches and theories that relates to individual differences in susceptibility of learned helplessness (LH). In the first part of the article the specificity of the learned helplessness syndrome is outlined. Next the theories that are relevant when individual differences in susceptibility of LH are concerned, are presented. Then the researches related to the role of three individual differences: attributional style, Locus of Control and sex, in susceptibility of LH are presented and discussed. In the last part of the article there are some conclusions from the presented researches. Also some conclusions about the possible directions of the future researches to help to separate the reactions to single failure from the reactions to helplessness training.
Agro-biological Characteristics and Biochemical Parameters of Purple Waxy Corn [Zea mays (L.) var certaina] in Son La Province, Vietnam
Authors: Thanh Hoang Van , Thinh Nguyen Quang , Thuan Nguyen Ðuc , Thao Le Thi , Hien Nguyen Thi Thu
Published: September 2023

Background: Local purple waxy corns, biocompound activity and nutrition content good for health, are growing from different districts and altitude of sea level in Sõn La province with various characters. It is essential for evaluation of agro-biological characteristics and nutritional composition of local purple waxy corns was to find out which is the best and suitable for rejuvenlination, market and production in Son La province. Methods: Field experiment was conducted following scientific principle of agricultural research and designed with random completed block design (RCBD) with three replications, a 20 m2 block area. Observations and quality analysis of main traits of 12 purple local waxy corns were analyzed in summer season of 2022. Result: Results showed various data of agro-biological characters, yield and biochemical kernel characters of twelve local purple waxy corns. SM8 local purple waxy corn variety showed the best agro-biological characters such as soluble protein 6.25 mg/g, total phenol 4.12 mg/g, chlorophyll stable index 89.5%, yield about 3.96 tons/ha, quality grain with starch content 68.63%, protein content 8.53% and anthocyanin content 315.03 mg/100 g. This variety can be a good option for the farmers to produce a variety with higher yield and good agro-biological characteristics.
EARLY DETECTION OF TUBERCULOSIS APPLICATION (E-TIBI): A NEW PARADIGM TO DETECT NEW CASE OF TUBERCULOSIS
Authors: Astha Triyono Erwin , Mahanani MVS , Anggraini Sulvy Dwi , Maulana Hafidh , Pratiwi Wahyu Dian , Yochanan Christian , Tan Feriawan , Masyfufah Lilis
Published: September 2023

Background: Tuberculosis (TB) is still one of the major health problems in the world, especially in countries with dense populations. Indonesia is listed among the top three countries with the highest burden of tuberculosis worldwide. The low coverage of case detection in Indonesia is one of the reasons for ineffective TB control. Therefore, this disease remains a threat to spread in today’s Indonesian society. Digital technology can be used to increase the effectiveness and efficiency of case detection. This study aims to create a new paradigm for detecting new cases of tuberculosis using a self-assessment website-based application. Methods: This descriptive quantitative research used univariate analysis. Respondents for this research were sampled from all East Java people who filled out the E-TIBI application. Result: In total, there were 4,658 E-TIBI users in East Java, with 20.80% suspected of tuberculosis. The most frequent symptoms found in the respondents were fatigue, cough for > 2 weeks, and weight loss. Discussion: A self-assessment paradigm based on digital technology was applied to the design of this E-TIBI application. From this application, the public can quickly determine whether they or others are suspected of having tuberculosis. This result shows that the whole community can easily access the E-TIBI application for initial tuberculosis screening. Conclusion: Through this application, direct community participation can increase the detection of new cases to support the government and WHO programs in eliminating tuberculosis by 2030.
ADOLESCENT KNOWLEDGE AND PERCEPTION OF HIV/ AIDS STIGMATIZATION IN THE INDONESIAN CONTEXT
Authors: Maris Bakara Stella , Sahara Lubis Elvi , Fitriani Yessy
Published: September 2023

Background: Stigmatization of People Living with HIV/AIDS (PLWHA) among adolescents today has become a significant barrier to preventing the increase of HIV/AIDS cases, including understanding those at risk and PLWHA themselves. Adolescents' knowledge and perceptions about PLWHA significantly influence HIV/AIDS stigma, given that adolescence signifies a phase of profound biological, psychological, and social transition. Objective: This research aims to determine the correlation between knowledge and perception of the stigma against people living with HIV/AIDS. Methods: This study utilizes secondary data from the Indonesian Demographic and Health Survey (IDHS) 2017, analyzed using a cross-sectional method. The sample consisted of 14,270 adolescents in Indonesia aged 15 to 24 years. The study employed questionnaires on HIV/AIDS knowledge, perception towards PLWHA, and stigma towards PLWHA. Data analysis was conducted using univariate analysis to observe frequency distribution and bivariate analysis with a chi-square test to examine the relationship between two variables. Results: The research results indicate a significant correlation between adolescents' knowledge and stigma towards PLWHA at 0.00 (p<0.05), as well as a significant correlation between adolescents' perception and stigma towards people with HIV/AIDS at 0.00 (p<0.05). Conclusion: Prevention efforts through education and comprehensive approaches in delivering health information in a way that is well-received by adolescents can be presented innovatively.
RISK FACTORS FOR THE INCIDENCE OF ANEMIA IN YOUNG WOMEN
Authors: Simatupang Nanda Agustian , Kalsum Ummi , Fitri Adelina , Agustia Dilma’aarij
Published: September 2023

Background: The prevalence of anemia in adolescents is still high in Jambi Province at 60.45%. Anemia can cause a decrease in body resistance and fitness, thereby inhibiting adolescent productivity. Purpose: Research objectives to determine the prevalence of anemia and risk factors for the incidence of anemia in young women. Methods: Cross-sectional research design, located in State Senior High School 8 of Jambi City from January to April 2019. Population 552 girls, with a sample of 83 girls in classes X and XI. The proportioned stratified random sampling technique was taken. The research variables were knowledge, breakfast, tablets, blood consumption, nutritional status, enhancing foods and iron absorption inhibitors, infectious diseases, and heavy meal frequency. The dependent variable was anemia. Interviews and secondary data from the measurement of Hb were conducted for primary data collection. Data would be analyzed with chi-square analysis. Results: The incidence of anemia among young women was 42.17%. There was relationship of knowledge (PR=2.05; 95% CI=1.30-3.24), blood tablet supplementation (PR=2.95; 95% CI =1.02-8.54), Breakfast (PR=3.03; 95% CI=1.41-6.48), and frequency of heavy eating (PR = 0.52; 95% CI=0.28-0.97) with the incidence of anemia. Conclusion: Factors associated with anemia among young women are knowledge, consumption of tablets plus blood, breakfast, and frequency of heavy eating.
JUSTIÇA AMBIENTAL E SUSTENTABILIDADE: ALERTAS E ESPERANÇAS
Authors: Murad Afonso , Tavares Sinivaldo
Published: September 2023

Até bem pouco tempo, “crise” se revestia de um caráter de excepcionalidade e de transitoriedade e, por essa razão, o termo era empregado para descrever situações de ruptura ou de passagem de uma época a outra. Recentemente, a palavra vem sendo usada em referência a uma situação permanente, a ponto de ser considerada a principal característica do “tempo presente”. Tem-se, inclusive, falado em crises, no plural; daí o neologismo policrise. E o elenco das inúmeras crises que nos assolam cresce sempre mais: crise econômica, crise financeira, crise alimentar, crise moral, crise existencial, crise sanitária (...)
DIGNIDADE, DIREITOS E CUIDADO: UMA LEITURA ECOTEOLÓGICA
Authors: Murad Afonso , Susin Luiz Carlos
Published: September 2023

Constatada a urgência ecológica de uma nova relação do ser humano com as outras criaturas, o artigo busca compreender a constituição de direitos e, na sua base, a categoria de dignidade. Para tanto, analisa a linguagem sobre a dignidade e um percurso histórico sobre a ampliação de reconhecimento de dignidade e direitos humanos. A partir dos animais, testa um reconhecimento alargado desses dois conceitos cada vez mais assimétricos. Dessa forma, a relação se transforma na gratuidade e na responsabilidade do Cuidado, assimétrico e interdependente, que configura, assim, um novo humanismo ecológico. Com Leonardo Boff e o Papa Francisco, o artigo sublinha as consequências dessa postura e os elementos teológico-pastorais de prática cristã do Cuidado. 
PALAVRAS-CHAVE: Direitos humanos. Humanismo. Ecologia. Cuidado.
BÍBLIA E SUSTENTABILIDADE: A CONSCIÊNCIA ECOLÓGICA COMO PARADIGMA DE UMA NOVA HERMENÊUTICA BÍBLICA
Authors: De Andrade Aila Luzia Pinheiro
Published: September 2023

As crises sociais, políticas e econômicas, extremos de secas e enchentes, e o aumento do nível do mar, são partes da crise ambiental contemporânea. Sendo assim, o artigo apresenta, inicialmente, algumas causas dessa crise, intimamente implicadas em um tipo de relação estabelecida entre o ser humano e a natureza, relação que se deu partir da reviravolta antropocêntrica na modernidade. O objetivo do artigo é mostrar que uma hermenêutica bíblica baseada na perspectiva antropocêntrica não é capaz de interpretar corretamente os textos bíblicos. O artigo defende, em primeiro lugar, que os relatos da criação não fundamentam nenhum domínio, no sentido de exploração desmedida, da natureza pelo ser humano. Em seguida, elucida que o sistema sabático na Bíblia, muitos séculos antes dos ambientalistas, já propunha uma forma de sustentabilidade, assegurando os recursos naturais para as futuras gerações e o cuidado com a criação inteira. Por fim, os resultados alcançados com a pesquisa apontam para a necessidade de um novo paradigma hermenêutico apto a interpretar a Bíblia não mais a partir de uma perspectiva antropocêntrica, mas de uma ótica enraizada numa consciência ecológica. Portanto, não se trata de uma mudança superficial na hermenêutica, mas de uma mudança de paradigma.
PALAVRAS-CHAVES: Cultura do consumo. Crise ambiental. Bíblia. Relatos da Criação. Sábado.
EL MAL Y LA DISTANCIA TRINITARIA EN DIOS, SEGÚN BALTHASAR. ¿RESPONSABILIDAD DE DIOS EN EL MAL?
Authors: Polanco Rodrigo
Published: September 2023

La realidad del mal ha sido siempre un gran enigma para la humanidad. Balthasar propone una teología trinitaria y soteriológica que introduce elementos novedosos en la comprensión del mal. En particular, el mal encuentra su condición de posibilidad en la distancia del amor dentro de la Trinidad. Esta posición, que he calificado de audaz, es evaluada en este estudio desde tres perspectivas: la ubicación del mal dentro del Teo-drama, una cierta fenomenología del mal/pecado, y el examen de lo que podría ser una cierta “responsabilidad” de Dios por la realidad del mal. ¿Es posible afirmar algo así?
PALABRAS CLAVE: mal, pecado, libertad, distancia amorosa, abandono de Dios.
CUATRO FORMAS DE INTERACCIÓN ENTRE CIENCIA Y RELIGIÓN. APORTES DESDE UNA PERSPECTIVA CRISTIANA
Authors: Rosales Diego
Published: September 2023

El objetivo de este artículo es mostrar que, en el fondo de la cuestión sobre las interacciones entre ciencia y religión, subyace un problema de racionalidad, tal como lo ha mostrado Joseph Ratzinger, y que ese problema se resuelve esclareciendo el objeto y el sentido de ambas. Para ello, comenzaré planteando la situación epistemológica de la ciencia y la religión después de la modernidad. Más tarde, explicaré tres paradigmas de interacción, a saber, los propuestos por Barbour, Gould y Peacocke, así como el modo en el que Ratzinger podría complementar dichas propuestas –que parecerían parciales–, e integrarlas o corregirlas bajo el paradigma de la racionalidad. Busco mostrar que esta lectura del pensamiento de Ratzinger permite plantear el problema de ciencia y religión desde unos términos que superan la perspectiva dialógica para plantearlos existencial y vitalmente.
PALABRAS CLAVE: Ratzinger. Racionalidad. Fe. Razón. Conocimiento. Interdisciplina
Formation of criteria for the selection of varieties of black currant by biochemical and technological potential for use in the production technology of jelly products
Authors: Myasishcheva N. V.
Published: September 2023

The expansion of domestic production of food products enriched with vitamins, biologically active substances, children's, dietary and functional nutrition products can be achieved thanks to the development of progressive technologies of breeding, cultivation, selection of raw materials with valuable biochemical, technological properties. Black currant berries have high antioxidant, jelly-forming properties and are widely used by processing enterprises for the production of fortified jelly products. At the same time, special attention is paid to the selection of varieties that are optimally suitable for this type of production. Thus, the purpose of these studies is aimed at identifying and systematizing the criteria for selecting varieties of black currant according to the technological and biochemical potential of berries for their involvement in the technology of production of jelly products of functional orientation with specified characteristics. Black currant berries of the Azhurnaya, Arapka, Iskusheniye, Kreolka, Ladushka, Ocharovaniye, Orlovskaya serenada (control) of the selection of the All-Russian Scientific Research Institute of Fruit Crop Breeding (VNIISPK), as well as jelly based on them were selected as objects of research. It was found that the developed jelly samples from black currant berries were characterized by high quality, satisfied the recommended daily intake of vitamin C by an average of 60%, vitamin P by 52.4%, pectin by 85.1%, and were characterized by a solid jelly-like structure without additional introduction of structure-forming agents. A positive correlation with a high degree of reliability between the rheological characteristics of jelly and indicators of the chemical composition of raw materials was revealed. Based on the comprehensive assessment of raw materials and jelly based on it, the criteria for the selection of varieties for a number of technological and biochemical characteristics are identified.
Optimization of the technology of high-viscosity liquid media using waste products from the oil and fat industry
Authors: Zheltoukhova E. Y. , Tronza P. A. , Terekhina A. V.
Published: September 2023

High-viscosity liquid media with desired properties are the product of complex processing of oil crops and waste products from oil and fat enterprises, so they must have the widest possible range of specialized characteristics. Highly viscous liquid media are becoming a more convenient and equally effective alternative to solid media. For this purpose, natural components can be introduced into their composition in the form of waste from the oil and fat industry, vegetable and essential oils. To create a competitive product, a modified technology was developed at the stage of introducing additives for the complex processing of oilseed cults and waste from oil and fat enterprises. The main additives were analyzed and natural components from the waste of the oil and fat industry, vegetable and essential oils were selected - tea tree oil, aloe vera gel, which have good anti-inflammatory, bactericidal, antifungal, antiviral and wound healing effects. Selected components are introduced into highly viscous liquid media in solubilized form, often in combination with other components. The composition of an experimental sample of high-viscosity liquid media - sodium laureth sulfate, cocamidopropyl betaine, cocamide DEA, sodium chloride, glyceryl, acrylate copolymer, methylchloroisothiazolinone methylisothiazolinone, citric acid, disodium EDTA, tea tree oil, aloe vera gel, triclocarban, fragrance, water was developed. During the experimental part, a step-by-step course for introducing components in the production of samples of high-viscosity liquid media was selected, the time for carrying out specific loading operations for each component in the production of high-viscosity liquid media was 15 minutes, the rotation speed of the stirrer was 45 rpm, and the temperature of the components at each stage of the process was 21 ℃
Simulation of municipal solid waste gasification in fixed bed reactor
Authors: Abd Allah Elrafie Ahmed , Mohamed El Hassan Yasir Awad Alla , Kasif A. Elhameed M. O. , Mohamed Salah Aldeen Ahmed
Published: September 2023

The objective of this work is simulating municipal solid waste gasification in fixed bed reactor. A comprehensive process model developed to simulate municipal solid waste (MSW) gasification in fixed bed reactor using an Aspen Plus  simulation .To predict and analyze the  municipal  solid  waste  pyrolysis and gasification process in an updraft fixed bed more veritably and appropriately, numerical modeling based on Gibbs energy minimization was executed using the Aspen plus software v(9). Rstoic is a block that can be used to simulate a reactor with the unknown or unimportant reaction kinetic  that  will  describe  drying  section(moisture evaporated).The Ryield model was  describe the pyrolysis section, while the Rgibbs model was used  for  gasification section individually .The  proposed  model is used to forecast and analyze target performance  parameter including syngas composition, lower heating value and carbon conversion rate under different conditions of  gasification temperature , and ratios. The results indicate that  is a good agreement between data and simulated data obtained using this model .The predicted  optimum  gasification temperature is about approximately 750°C, and the best ratio  of air equivalent ratio is around 0.2 and feed rate 200 kg /hr.
Modification of mineral filler with organosilanes in a polymer composition for road marking
Authors: Talalai V. V. , Borisova N. V. , Artemenko A. A. , Vasiliev Y. E.
Published: September 2023

Currently, the use of polymer composite materials for road markings, in particular thermoplastics based on petroleum polymer resins, is promising. The effectiveness of the use of such road marking materials and their service life mainly depend on the formulations of thermoplastic compositions for marking and technologies for their production. The purpose of this work was to evaluate the adhesive interaction of microdolomite modified by organosilanes and thermoplastic petroleum polymer resin to impart increased operational properties of the road marking composition. To increase the adhesive affinity in the polymer system:filler it is proposed to modify the microdolomite with organosilane of the AGM-9 brand, which contains a hydrolyzable silicon-functional group and a non-hydrolyzable organofunctional group in the composition of the bifunctional molecule, which provides organofunctional properties to the inorganic surface of the filler. To create marking thermoplastics with a long service life in this work, it was proposed to use a combined combination of modified and unmodified microdolomite. It was discovered that the mixture of modified and unmodified microdolomite in the range of 10-15:85-90 leads to an increase in strength up to 7 MPa, which is higher than the permissible value of at least 5 MPa, while the ability to strain stretching and elongation at break decreases from 5 to 3%, which is also higher than the permissible value of at least 3%. The developed composite marking material based on domestic petroleum polymer resin and a combined filler of the MD40 brand with a combination of modified and unmodified microdolomite in a ratio of 12.5:87.5 has optimal strength-elasticity characteristics that meet the requirements for road marking materials and long-term abrasion resistance of up to 4 thousand cycles.
Optimization of the production process through the introduction of lean production methods
Authors: Denisova Y. V. , Petrova A. S. , Sopin V. F.
Published: September 2023

In conditions of severe political pressure on the Russian economy, sanctions and instability, enterprises in many industries are on the verge of survival. That is why the issues of optimizing all processes and reducing losses are becoming especially relevant now. A higher level of production efficiency can be ensured by the introduction of lean production tools and methods at enterprises. The authors of the article consider the practice of applying the concept of lean production in foreign and Russian companies, conduct a comparative analysis of the main indicators obtained from the implementation of saving technologies in them, identify the reasons for the lag of domestic enterprises according to these indicators. The article notes that, unfortunately, a significant number of defective products, the presence of excessive stocks and excessive duration of the production cycle still remain characteristic of most Russian enterprises. The basis of the research in the article is the enterprise "FKP "NPO "Kazan Precision Engineering Plant", which is at the initial stages of the implementation of this concept. On the example of the fuse housing, the optimization of the production process for its manufacture is considered in detail. The general procedure for carrying out these works is outlined, which consists in systematizing production losses, identifying the main problems that cause them, determining the rank of problems and developing a set of measures to eliminate them using lean production methods. Further, for each identified problem, solutions are proposed and their impact on production is determined. It is noted that the total economic effect of the implementation of these measures will be approximately 47%, which proves the need to continue this work in other areas of production.
Analysis of the build-up of the military power of the state
Authors: Orekhova N. V. , Kudryavtseva N. N. , Pakhomova Y. V. , Duvanova Y. N.
Published: September 2023

The work noted the relevance of the chosen topic at present, related to the ever-increasing world military budgets. The importance of the index of military power was emphasized, an analysis of its values in dynamics over the past 3 years was carried out in the context of the countries at the top of the rating. A methodology for calculating parameters related to the military power of the state is proposed - one of the strongest means of achieving political goals. Based on the analysis of the military power of the state, a mechanism for the functioning and development of military potential in cooperation with structural components within the framework of the total potential is presented. The military power of the state is, along with the structural components considered, a set of individual elements and organizations that function and perform their specific tasks. To create and ensure the effective functioning of this set of organizations, the amount of forces and means that forms the military power of the state is used. The relationship between the level of military potential, the state of the Armed Forces and the parties to the public life of the state was studied. The reasons for the high rating of military power in the USA, Russia, China, India and Japan in modern conditions have been identified. The general trend of the military power index values in the analyzed countries for 2019-2021 has been analyzed. Economic problems of increasing military power were noted and possible directions of their solution were indicated
Improving the efficiency of cooling towers in the water cycle
Authors: Shishatskii Y. I. , Nickel S. A. , Derkanosova A. A. , Tolstov S. A. , Panchenko S. L.
Published: September 2023

Cooling towers are the main equipment of the water cycle. Cooling is carried out by the circulating water of heat exchange devices. The heated water is cooled in cooling towers by mixing with the air flow and again directed to use as a cooling agent. Cooling is carried out as a result of heat exchange. The driving force necessary to overcome the friction force of the flows, which interferes with the flow of air, is provided by injection or exhaust fans. The total driving force can be expressed as the sum of the individual driving forces in the air and water flows. The work with air mixing of the liquid phase is carried out due to the energy of compressed air and can be calculated as the work of isothermal compression according to the equations given in the work. Cooling towers of various types are known. Fan cooling towers are the most advanced type of water coolers, since they provide practically stable cooling of water by changing the fan speed or their periodic shutdown, they allow higher thermal loads and deep cooling of water, that is, a greater approximation of the temperature of the cooled water to the theoretical cooling limit due to the increased relative air flow passing through the cooling tower. The main characteristics of cooling towers in terms of irrigation area, hydraulic load, etc. are given. A diagram of a fan cooling tower is presented, its main advantages are listed, such as cooling capacity, intensification of mass transfer (water) to another (air), that is, a typical process of coupled heat and mass transfer. The main elements of the cooling tower are considered. The sprinkler, as the main element of the cooling tower, is necessary to increase the contact surface between water and air, accelerate the cooling process. The ways of increasing the efficiency of their operation are shown. Water traps minimize drip entrainment – up to 100%. Water distribution systems should evenly distribute the cooled water over the surface area of the sprinkler. The energy consumption coming through the nozzles is presented. The role of entrance windows as elements of a cooling tower is highlighted, the main directions for further improving the efficiency of modern cooling towers.
Optimization of investment resource flows for the development of innovative activities at the enterprise
Authors: Anisimov Y. P. , Kuksova I. V. , Gubertov E. A. , Zhilnikov A. Y. , Igolkin I. S.
Published: September 2023

The article deals with issues related to optimizing the flows of investment resources for the development of innovative activities at the enterprise. The purpose of optimizing the flows of investment resources for the development of innovative activities at the enterprise is to increase the efficiency of activities, expressed in capturing commercial markets through the introduction of competitive innovative products and increasing the profitability of investments, as well as in maintaining the qualifications of personnel and efficient and timely renewal of production assets. Consequently, the optimization of innovation and investment activities at enterprises will be such coordinated and mutually conditional strategies for directing investment resources and selecting innovative projects, in which the enterprise will be able to achieve its strategic goals under conditions of continuity of the innovation process and uninterrupted financing, which will allow the enterprise to offer new developments and upgraded products in time, responding to the requirements of customers in more perfect products. The authors conducted a factor-by-factor integral investment analysis, which allowed us to determine the degree of dependence of the volume of investments in innovation. The practical significance of the study lies in the fact that the evaluation results can serve as an information base for making managerial decisions that allow to activate the development of investment processes at the enterprise.
Development of a yogurt with antioxidant properties based on the use of encapsulated taxifolin
Authors: Fatkullin R. I. , Kalinina I. V. , Popova N. V. , Naumenko N. V. , Naumenko E. E.
Published: September 2023

The aim of this study was to investigate the possibility of using plant antioxidants to produce probiotic products with antioxidant properties. The probiotic food system chosen was yoghurt produced by a thermostatic process using commercially available yoghurt sourdough. Being a mass-market product, yoghurt with antioxidant properties may become an adequate approach to solve the problems of providing the population with biologically active minor substances of antioxidant action. One of the important challenges in the development of fortified probiotic products is to assess the impact of the food ingredients used on probiotic development and the formation of a given quality of the product itself. For this reason, the research assessed indicators such as titratable acidity, which characterizes the course of the fermentation process; the content of probiotic microorganisms in combination with the study of their morphology; and antioxidant activity as an indicator reflecting the formation of new functional properties. Taxifolin powder in the original and encapsulated form (in hydroxypropyl-beta-cyclodextrin) according to the author's methodology was used as an antioxidant. The results of studies show that inclusion of taxifolin into the composition of yogurt ensures formation of probiotic product with the required amount of probiotic microorganisms (not less than 107 CFU per 1 g) and the titratable acidity level according to the current regulatory documentation. It was found that the use of taxifolin in encapsulated form provides a better development of the fermentation microflora of yoghurt, the content of probiotic microorganisms was one order of magnitude higher than in the sample with unencapsulated taxifolin. The value of antioxidant activity of the enriched yoghurt samples was more than 2 times higher than that of the control sample. Thus, the results obtained showed that when obtaining yoghurt with antioxidant properties it is most advisable to add a food ingredient based on encapsulated taxifolin.