bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification, Characteristics and Function of Phosphoglucomutase (PGM) in the Agar Biosynthesis and Carbon Flux in the Agarophyte Gracilariopsis lemaneiformis (Rhodophyta)
Authors: Chen Qionglin , Yu Xinlei , Liu Shixia , Luo Suya , Chen Xiaojiao , Xu Nianjun , Sun Xue
Published: July 2022

Agar is widely applied across the food, pharmaceutical and biotechnology industries, owing to its various bioactive functions. To better understand the agar biosynthesis in commercial seaweed Gracilariopsis lemaneiformis, the activities of four enzymes participating in the agar biosynthesis were detected, and phosphoglucomutase (PGM) was confirmed as highly correlated with agar accumulation. Three genes of PGM (GlPGM1, GlPGM2 and GlPGM3) were identified from the G. lemaneiformis genome. The subcellular localization analysis validated that GlPGM1 was located in the chloroplast and GlPGM3 was not significantly distributed in the organelles. Both the GlPGM1 and GlPGM3 protein levels showed a remarkable consistency with the agar variations, and GlPGM3 may participate in the carbon flux between (iso)floridoside, floridean starch and agar synthesis. After treatment with the PGM inhibitor, the agar and floridean starch contents and the activities of floridean starch synthase were significantly decreased; products identified in the Calvin cycle, the pentose phosphate pathway, the Embden-Meyerhof-Parnas pathway and the tricarboxylic acid cycle were depressed; however, lipids, phenolic acids and the intermediate metabolites, fructose-1,6-phosphate were upregulated. These findings reveal the essential role of PGM in regulating the carbon flux between agar and other carbohydrates in G. lemaneiformis, providing a guide for the artificial regulation of agar accumulation.
Combined Score of Perivascular Space Dilatation and White Matter Hyperintensities in Patients with Normal Cognition, Mild Cognitive Impairment, and Dementia
Authors: Zdanovskis Nauris , Platkājis Ardis , Kostiks Andrejs , Šneidere Kristīne , Stepens Ainārs , Naglis Roberts , Karelis Guntis
Published: July 2022

Background and Objectives: Cerebral perivascular spaces (PVS) are part of the cerebral microvascular structure and play a role in lymphatic drainage and the removal of waste products from the brain. White matter hyperintensities (WMH) are hyperintense lesions on magnetic resonance imaging that are associated with cognitive impairment, dementia, and cerebral vascular disease. WMH and PVS are direct and indirect imaging biomarkers of cerebral microvascular integrity and health. In our research, we evaluated WMH and PVS enlargement in patients with normal cognition (NC), mild cognitive impairment (MCI), and dementia (D). Materials and Methods: In total, 57 participants were included in the study and divided into groups based on neurological evaluation and Montreal Cognitive Assessment results (NC group 16 participants, MCI group 29 participants, D group 12 participants). All participants underwent 3T magnetic resonance imaging. PVS were evaluated in the basal ganglia, centrum semiovale, and midbrain. WMHs were evaluated based on the Fazekas scale and the division between deep white matter (DWM) and periventricular white matter (PVWM). The combined score based on PVS and WMH was evaluated and correlated with the results of the MoCA. Results: We found statistically significant differences between groups on several measures. Centrum semiovale PVS dilatation was more severe in MCI and dementia group and statistically significant differences were found between D-MCI and D-NC pairs. PVWM was more severe in patients with MCI and dementia group, and statistically significant differences were found between D-MCI and D-NC pairs. Furthermore, we found statistically significant differences between the groups by analyzing the combined score of PVS dilatation and WMH. We did not find statistically significant differences between the groups in PVS dilation of the basal ganglia and midbrain and DWM hyperintensities. Conclusions: PVS assessment could become one of neuroimaging biomarkers for patients with cognitive decline. Furthermore, the combined score of WMH and PVS dilatation could facilitate diagnostics of cognitive impairment, but more research is needed with a larger cohort to determine the use of PVS dilatation and the combined score.
Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells
Authors: Saleh Tareq , As Sobeai Homood M. , Alhoshani Ali , Alhazzani Khalid , Almutairi Mashal M. , Alotaibi Moureq
Published: July 2022

Background and Objectives: The development of radioresistance is a fundamental barrier to successful glioblastoma therapy. Autophagy is thought to play a role in facilitating the DNA repair of DNA damage foci in radiation-exposed tumor cells, thus, potentially contributing to their restoration of proliferative capacity and development of resistance in vitro. However, the effect of autophagy inhibitors on DNA damage repair is not fully clear and requires further investigation. Materials and Methods: In this work, we utilized M059K (DNA-PKcs proficient) and M059J (DNA-PKcs deficient) glioma cell lines to investigate the role of autophagy inhibitors in the DNA repair of radiation-induced DNA damage. Cell viability following radiation was determined by trypan blue exclusion in both cell lines. Cell death and autophagy assays were performed to evaluate radiation-induced cell stress responses. DNA damage was measured as based on the intensity of phosphorylated γ-H2AX, a DNA double-stranded breaks (DSBs) marker, in the presence or absence of autophagy inhibitors. Results: The cell viability assay showed that M059J cells were more sensitive to the same dose of radiation (4 Gy) than M059K cells. This observation was accompanied by an elevation in γ-H2AX formation in M059J but not in M059K cells. In addition, the DAPI/TUNEL and Senescence-associated β-galactosidase (SA-β-gal) staining assays did not reveal significant differences in apoptosis and/or senescence induction in response to radiation, respectively, in either cell line. However, acridine orange staining demonstrated clear promotion of acidic vesicular organelles (AVOs) in both cell lines in response to 4 Gy radiation. Moreover, DNA damage marker levels were found to be elevated 72 h post-radiation when autophagy was inhibited by the lysosomotropic agent bafilomycin A1 (BafA1) or the PI3K inhibitor 3-methyl adenine (3-MA) in M059K cells. Conclusions: The extent of the DNA damage response remained high in the DNA-PKcs deficient cells following exposure to radiation, indicating their inability to repair the newly formed DNA-DSBs. On the other hand, radioresistant M059K cells showed more DNA damage response only when autophagy inhibitors were used with radiation, suggesting that the combination of autophagy inhibitors with radiation may interfere with DNA repair efficiency.
The Treatment Strategy for the Atrial Septal Defect in the Presence of Severe Pulmonary Hypertension
Authors: Zarambaitė Evelina , Ramantauskaitė Grytė , Krivickienė Aušra , Siudikas Adakrius , Miliauskas Skaidrius , Ereminienė Eglė
Published: July 2022

Atrial septal defect is one of the most common congenital heart diseases in adults. The defect often leads to volume overload in the right heart coupled with the potential risk of right heart failure and pulmonary arterial hypertension. These conditions lead to worsening in quality of life, decrease in physical capacity, and even to fatal outcomes. The main strategy for treatment of atrial septal defect is a transcatheter or surgical closure of the defect, but in patients with severe pulmonary arterial hypertension, it is recommended to manage pulmonary arterial hypertension and after that treat the defect invasively. This strategy is called “treat and repair” strategy. We present an illustrative case report of management and treatment of atrial septal defect, complicated with severe pulmonary arterial hypertension. In this case, surgical closure of the defect was contraindicated because of the high pulmonary vascular resistance. Therefore, the “treat and repair” strategy was approached. After specific medical treatment of pulmonary arterial hypertension, surgical closure of the defect was chosen and proven successful.
Antibody Responses after Two Doses of COVID-19 mRNA Vaccine in Dialysis and Kidney Transplantation Patients Recovered from SARS-CoV-2 Infection
Authors: Cappuccilli Maria , Semprini Simona , Fabbri Elisabetta , Fantini Michela , Bruno Paolo Ferdinando , Spazzoli Alessandra , Righini Matteo , Flachi Marta , La Manna Gaetano , Sambri Vittorio , Mosconi Giovanni
Published: July 2022

Background and Objectives: Hemodialysis patients (HD) and kidney transplant recipients (KTRs) have been heavily impacted by COVID-19, showing increased risk of infection, worse clinical outcomes, and higher mortality rates than the general population. Although mass vaccination remains the most successful measure in counteracting the pandemic, less evidence is available on vaccine effectiveness in immunodepressed subjects previously infected and recovered from COVID-19. Materials and Methods: This study aimed at investigating the ability to develop an adequate antibody response after vaccination in a 2-dose series against SARS-CoV-2 in HD patients and KTR that was administered after laboratory and clinical recovery from COVID-19. Results: Comparing SARS-CoV-2 S1/S2 IgG levels measured before and after 2 doses of mRNA vaccine (BNT162b2 vaccine, Comirnaty, Pfizer–BioNTech or mRNA-1273 vaccine, Spikevax, Moderna), highly significant increases of antibody titers were observed. The antibody peak level was reached at 3 months following second dose administration, regardless of the underlying cause of immune depression and the time of pre-vaccine serology assessment after negativization. Conclusions: Our data indicate that HD patients and KTR exhibit a satisfying antibody response to a 2-dose series of mRNA vaccine, even in cases when infection-induced humoral immunity was poor or rapidly fading. Further studies are needed to evaluate the role of booster doses in conferring effective and durable protection in weak patient categories.
Towards Biohybrid Lung Development: Establishment of a Porcine In Vitro Model
Authors: Schlör Simon , Pflaum Michael , Höffler Klaus , Kühn Christian , Haverich Axel , Wiegmann Bettina
Published: July 2022

Lung transplantation (LTx) is the only curative therapy option for patients with end-stage lung diseases, though only available for chosen patients. To provide an alternative treatment option to LTx, we aim for the development of an implantable biohybrid lung (BHL) based on hollow fiber membrane (HFM) technology used in extracorporeal membrane oxygenators. Crucial for long-lasting BHL durability is complete hemocompatibility of all blood contacting surfaces, which can be achieved by their endothelialization. In continuation to successful in vitro investigations using human endothelial cells (ECs), indicating general feasibility, the appropriate porcine in vivo model needs to be prepared and established to fill the translational data gap prior to patient’s application. Therefore, isolation of porcine ECs from carotid arteries (pCECs) was established. Following, pCECs were used for HFM endothelialization and examined under static and dynamic conditions using cell medium or heparinized blood, to assess their proliferation capacity, flow resistance and activation state, especially under clinically relevant conditions. Additionally, comparative hemocompatibility tests between native and endothelialized HFMs were performed. Overall, pure pCECs formed a viable and confluent monolayer, which resisted applied flow conditions, in particular due to physiological extracellular matrix synthesis. Additionally, pCECs remained the non-inflammatory and anti-thrombogenic status, significantly improving the hemocompatibility of endothelialized HFMs. Finally, as relevant for reliable porcine to human translation, pCECs behaved in the same way as human ECs. Concluding, generated in vitro data justify further steps towards pre-clinical BHL examination, in particular BHL application to porcine lung injury models, reflecting the clinical scenario with end-stage lung-diseased patients.
Controlled Thin Polydimethylsiloxane Membrane with Small and Large Micropores for Enhanced Attachment and Detachment of the Cell Sheet
Authors: Jang Yeongseok , Kim Hyojae , Jung Jinmu , Oh Jonghyun
Published: July 2022

Polydimethylsiloxane (PDMS) membranes can allow the precise control of well-defined micropore generation. A PDMS solution was mixed with a Rushton impeller to generate a large number of microbubbles. The mixed solution was spin-coated on silicon wafer to control the membrane thickness. The microbubbles caused the generation of a large number of small and large micropores in the PDMS membranes with decreased membrane thickness. The morphology of the thinner porous PDMS membrane induced higher values of roughness, Young’s modulus, contact angle, and air permeability. At day 7, the viability of cells on the porous PDMS membranes fabricated at the spin-coating speed of 5000 rpm was the highest (more than 98%) due to their internal networking structure and surface properties. These characteristics closely correlated with the increased formation of actin stress fibers and migration of keratinocyte cells, resulting in enhanced physical connection of actin stress fibers of neighboring cells throughout the discontinuous adherent junctions. The intact detachment of a cell sheet attached to a porous PDMS membrane was demonstrated. Therefore, PDMS has a great potential for enhancing the formation of cell sheets in regenerative medicine.
The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium
Authors: Jung Mijin , Pan Xiaobei , Cunningham Emma L. , Passmore Anthony P. , McGuinness Bernadette , McAuley Daniel F. , Beverland David , O’Brien Seamus , Mawhinney Tim , Schott Jonathan M. , Zetterberg Henrik , Green Brian D.
Published: July 2022

The mechanisms underlying the occurrence of postoperative delirium development are unclear and measurement of plasma metabolites may improve understanding of its causes. Participants (n = 54) matched for age and gender were sampled from an observational cohort study investigating postoperative delirium. Participants were ≥65 years without a diagnosis of dementia and presented for primary elective hip or knee arthroplasty. Plasma samples collected pre- and postoperatively were grouped as either control (n = 26, aged: 75.8 ± 5.2) or delirium (n = 28, aged: 76.2 ± 5.7). Widespread changes in plasma metabolite levels occurred following surgery. The only metabolites significantly differing between corresponding control and delirium samples were ornithine and spermine. In delirium cases, ornithine was 17.6% higher preoperatively, and spermine was 12.0% higher postoperatively. Changes were not associated with various perioperative factors. In binary logistic regression modeling, these two metabolites did not confer a significantly increased risk of delirium. These findings support the hypothesis that disturbed polyamine metabolism is an underlying factor in delirium that warrants further investigation.
Evolution of Sulfidic Legacy Mine Tailings: A Review of the Wheal Maid Site, UK
Authors: Fitch Verity , Parbhakar-Fox Anita , Crane Richard , Newsome Laura
Published: July 2022

Historic tailings dams and their associated mine waste can pose a significant risk to human and environmental health. The Wheal Maid mine site, Cornwall, UK, serves as an example of the temporal evolution of a tailings storage facility after mining has ceased and the acid-generating waste subjected to surficial processes. This paper discusses its designation as a contaminated land site and reviews our current understanding of the geochemistry, mineralogy, and microbiology of the Wheal Maid tailings, from both peer-reviewed journal articles and unpublished literature. We also present new data on waste characterisation and detailed mineral chemistry and data from laboratory oxidation experiments. Particularly of interest at Wheal Maid is the presence of pyrite-bearing “Grey Tailings”, which, under typical environmental conditions at the Earth’s surface, would be expected to have undergone oxidation and subsequently formed acidic and metalliferous mine drainage (AMD). The results identified a number of mechanisms that could explain the lack of pyrite oxidation in the Grey Tailings, including a lack of nutrients inhibiting microbial Fe(II) oxidation, passivation of pyrite mineral surfaces with tailings processing chemicals, and an abundance of euhedral pyrite grains. Such research areas need further scrutiny in order to inform the design of future tailings facilities and associated AMD management protocols.
Methodological approaches to assessing the implementation of state programs to achieve the priorities of the socio-economic development of the Russian Federation
Authors: Gumerov R. R. , Guseva N. V. , Lysenko A. A.
Published: July 2022

Decree of the President of the Russian Federation № 633 dated November 8, 2021 among the main directions of state policy in this area, determines the scientific and methodological support for strategic planning of socio-economic development and ensuring national security [2]. Currently, the minimum necessary regulatory and legal framework has been formed for the preparation and implementation of state programs of the Russian Federation. The named Presidential Decree established the architecture of strategic planning documents. Decree of the Government of the Russian Federation № 786 of May, 26, 2021 regulates the general rules for the development, implementation, monitoring and evaluation of the effectiveness of state programs of the Russian Federation [4]; Decree of the Government of the Russian Federation № 903 of July 17, 2019 approved uniform rules for the formation of a Consolidated Annual Report on the progress of implementation and evaluation of the effectiveness of state programs of the Russian Federation [3]. At the same time, there are gaps in the regulatory support for the preparation and implementation of state programs that do not allow us to correctly assess the quality of state programs, which primarily means (but is not limited to) their impact on achieving long-term priorities of socio-economic development of the Russian Federation. Earlier, the authors outlined the main methodological approaches to assessing the quality of government programs, the algorithm and tools for conducting an assessment, and also published the main results of testing the recommended assessment model [7, 8]. This article develops the author's ideas of qualitative analysis of the links between the goals and indicators (target block) of state programs of the Russian Federation with the priorities of socio-economic development of the country and offers quantitative methods of their assessment. In general, a series of articles by the authors describes a "line" of models that allow a comprehensive quantitative assessment of the qualitative characteristics of state programs of the Russian Federation.
Sifat Preservasi Lingkaran dan Garis Pada Transformasi Möbius
Authors: Muhammad Guntur Maulana , Ihsan Iden Rainal , Priyanda Roni
Published: July 2022

This article discusses Möbius transformation from the point of view of algebra to describe one of its geometric properties, i.e. preserving circles and lines in complex planes. In simple terms, this preservation means that Möbius transformation maps a collection of circles and lines (back) into a collection of circles and lines. In general, the discussion begins with an explanation of the definition of the Möbius transformation in the complex plane. The discussion continues on defining the basic mapping and direct affine transformation. These two concepts are used to prove the existence of the preservation properties of circles and lines in the Möbius transformation. It can be shown that the Möbius transformation can be expressed as a composition of the direct affine transform and the inverse. It can also be shown that the direct affine transform and the inverse both have the property of preserving circles and lines in the complex plane. Thus, it can be concluded that in this study the Möbius transformation has the property of preserving circles and lines in the complex plane.
Sistem Chaos Model Risiko Keuangan: Analisis Dinamik
Authors: Yuningsih Siti Hadiaty , Sukono Sukono , Rusyaman Endang
Published: July 2022

Chaos phenomena appear in dynamic, nonlinear and deterministic systems. One model that is being intensively researched is financial risk. This model has system variables such as interest rate, investment demand, and stock price index. This study shows that the new financial system has interesting characteristics including multistability equilibrium points, Lyapunov exponents and bifurcation diagrams. The results of this study use MATLAB for phase diagrams of the financial system. The Lyapunov exponent and analysis of the Bifurcation diagram have been generated showing the chaotic phenomena in the intervals 0 a 15 and 0 b 0.25. The resulting Kaplan-Yorke dimension is 2.2506. The results of this study can be used to predict financial risk chaos.
Bifurkasi Pada Model Penyebaran Penyakit MERS-CoV di Dua Wilayah dengan Populasi Konstan
Authors: Owen Livia
Published: July 2022

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is caused by a novel coronavirus and it can be a human-to-human transmission disease. World Health Organization (WHO) reported the disease outbreak first happened in Saudi Arabia in 2012 and the last case is reported in 2019. In 2018, MERS-CoV outbreaks were reported in the Republic of Korea, United Kingdom of Great Britain, Northern Ireland, Saudi Arabia, Uni Arab Emirates, Oman, and Malaysia. Cases that are identified outside the Middle East are usually caused by traveling people who were infected in the Middle East and then traveled back to their country. The previous research had constructed a mathematical model for the transmission of MERS-CoV in two areas by separating the human population into susceptible and infectious groups. It focused on the basic reproductive number and sensitivity analysis. In this paper, we simplify the model with the assumption that the total population of each area is constant. Using Lagrange Multiplier Method, we find some co-dimension one and co-dimension two bifurcations i.e.fold bifurcation and cusp bifurcation, respectively. We get the domain of parameters where three, two and one non-trivial equilibrium point occurs. We also find a transcritical bifurcation point such that the disease-free equilibrium point is stable on some parameter domains.
Dampak Perubahan Index Inflasi pada Perhitungan Premi Excess-of-Loss Menggunakan Metode Burning Cost
Authors: Novika Fanny , Kalla Yusuf Hidayat , Yuliana Elvira
Published: July 2022

Based on OJK data on insurance statistical documents in 2020 and 2021, the adequacy of reinsurance company premiums continued to decline throughout the year until the year 2020 a slight excess of 164.60% and 183,31% at the end of 2021. Analysis of proper premium calculation needs to be done as an effort to prevent the default from insurance companies, one of which is fire insurance with Burning Cost. The purpose of this study is to determine the impact of the inflation index that can make changes to the calculation of premiums using Burning Cost. This study uses secondary data on the value of fire insurance claims at reinsurance companies by observing historical reports of claim data from the previous year. The use of the inflation index in calculating the Excess-of-Loss premium using the Burning Cost method has a different value if it is not assumed. The more inflation index used, the higher the premium that will be charged to the ceding company.
A Fractional-Order Predator-Prey Model with Age Structure on Predator and Nonlinear Harvesting on Prey
Authors: Panigoro Hasan S. , Resmawan Resmawan , Sidik Amelia Tri Rahma , Walangadi Nurdia , Ismail Apon , Husuna Cabelita
Published: July 2022

In this manuscript, the dynamics of a fractional-order predator-prey model with age structure on predator and nonlinear harvesting on prey are studied. The Caputo fractional-order derivative is used as the operator of the model by considering its capability to explain the present state as the impact of all of the previous conditions. Three biological equilibrium points are successfully identified including their existing properties. The local dynamical behaviors around each equilibrium point are investigated by utilizing the Matignon condition along with the linearization process. The numerical simulations are demonstrated not only to show the local stability which confirms all of the previous analytical results but also to show the existence of periodic signal as the impact of the occurrence of Hopf bifurcation.
Fractura supracondílea del húmero en el niño y su tratamiento incruento
Authors:   , Piñeyro Leandro Félix
Published: July 2022

Dentro de la traumatología de la extremidad inferior del húmero, la fractura supracondílea es la más frecuente en niños y adolescentes. La característica fundamental nos la dá el fragmento articular que bien puede estar desplazado hacia adelante -mecanismo por flexión, raro- o hacia atrás -mecanismo por extensión, frecuente.
Peningkatan Ketahanan Pangan Bagi Masyarakat Terdampak Covid-19
Authors: Andini Lidia , Prajogo Uke , Bunyamin Bunyamin , Munfaqiroh Siti , Muslichah Muslichah , Ratnasari Siwi dyah , Haji Son , Sunarto Sunarto , Syadeli M , Sugiono Djoko , Rahmania Benita
Published: July 2022

Tujuan Kegiatan  Pengabdian Kepada Masyarakat: 1) Meningkatkan ketersediaan pangan bagi masyarakat terdampak Covid-19, 2) Memberikan pengetahuan dan ketrampilan kepada pengelola Pondok Pesantren El-Jasmeen mengenai teknik  budidaya sayur di dalam pot secara organik, 3) Memberikan pengetahuan dan ketrampilan mengenai teknik pascapanen pengolahan sayur  menjadi produk olahan yang bernilai ekonomi tinggi. Hasilnya, pengetahuan dan keterampilan pengelola mengenai teknik budidaya sayur dalam pot dan pascapanennya mengalami peningkatan. Pengelola Pondok Pesantren El-Jasmeen dapat membudidayakan tanaman sayur secara baik dan mampu mengolahnya menjadi produk olahan es krim sayur yang enak dan bernilai ekonomi tinggi. Kegiatan pengabdian kepada masyarakat ini berdampak kepada ketahanan pangan dan peningkatan taraf ekonomi masyarakat di era pandemi Covid-19 karena dapat dikembangkan menjadi usaha skala rumah tangga.
Patterns in Number of Property Transactions of Pre-War Shophouse Case Study: Penang, Malacca, and Kelantan
Authors: Azmi Fatin Afiqah Md. , Maimun Nurul Hana Adi
Published: July 2022

Objective - Economic sustainability of heritage property can be measured through an active property transaction of a pre-war shophouse in the study areas. This paper investigates the breakdown of a number of pre-war shophouse transactions in Penang, Malacca, and Kelantan.
Methodology/Technique – The documentary method notably the Annual Property Market Report was collected and analysed.
Finding – The results demonstrated that in Penang, the pre-war shophouse sub-sector saw mixed movements in the number of transactions while the commercial property-like pre-war shophouse sub-market was generally stable in Malacca and in Kelantan’s commercial sub-sector, the pre-war shophouse performed moderately in the review period.
Novelty – These patterns of a number of property transactions of a pre-war shophouse in three study areas proved that the heritage property has a sustainable market value.

Type of Paper: Review
JEL Classification: D23, D29.
Keywords: Economic Thought; Heritage; Market Value; Property Transaction; Real Estate; Sustainable
Reference to this paper should be referred to as follows: Azmi, F.A.M; Maimun, N.H.A. (2022). Patterns in Number of Property Transactions of Pre-War Shophouse Case Study: Penang, Malacca and Kelantan, GATR-Global J. Bus. Soc. Sci. Review, 10(2), 72–76. https://doi.org/10.35609/gjbssr.2022.10.2(1)
Kreatywność w pracy nauczycieli w dobie pandemii – sztuka, konieczność, a może wyzwanie?
Authors: Nosek-Kozłowska Katarzyna
Published: July 2022

Tekst ma na celu ukazanie pracy nauczycieli w dobie pandemii w odniesieniu do kompetencji, którą stanowi kreatywność. Teoretyczny namysł obejmuje charakterystykę merytoryczną zawodu nauczyciela oraz możliwości realizacji kształcenia na odległość w sytuacji pandemii. Problematyka została ujęta w postaci następujących pytań: Jak wygląda praca nauczycieli w dobie pandemii? W jaki sposób pandemia wpływa na jakość realizacji procesu kształcenia? Jakie metody i narzędzia pracy wykorzystują nauczyciele w dobie pandemii? W jaki sposób badani nauczyciele rozumieją pojęcie kreatywności i jak ujawnia się ona w ich pracy? Punktem wyjścia do podjętych analiz były wyniki badań empirycznych dotyczące wskazanego problemu. Na potrzeby zgromadzenia materiału empirycznego wykorzystano metodę studium przypadków oraz zastosowano technikę wywiadu narracyjnego skoncentrowanego na problemie. Badania były prowadzone wśród nauczycieli różnych szczebli edukacji pochodzących z województwa warmińsko-mazurskiego. Zastosowano celowy dobór badanych. Wyniki są prezentowane na łamach artykułu w sposób wybiórczy. Refleksja nad podjętą problematyką wskazuje na fakt, iż współcześni nauczyciele są kreatywni. Stopień, w jakim ta cecha wpływa na ich działalność zawodową, zależy od ich zaangażowania w kształcenie młodego pokolenia, ale także od posiadanych przez nich cech osobowościowych. Kreatywność jest kompetencją nauczyciela XXI wieku, może być sztuką, ale też koniecznością.
Design of an ultra-sensitive and miniaturized diamond NV magnetometer based on a nanocavity structure
Authors: Katsumi Ryota , Sekino Masaki , Yatsui Takashi
Published: July 2022

The ensemble of nitrogen-vacancy (NV) centers in diamond allows for the potential realization of the sensitive magnetometers by leveraging their excellent spin properties. However, the NV-based magnetometers are limited by their experimental magnetic field sensitivity owing to its inefficient photon collection. Moreover, they are a disadvantage to the reduced spatial resolution and excessive excitation power. To overcome these issues, we propose a ultra-sensitive diamond magnetometer based on nanocavities. The device structure can attain a high collective efficiency and enhance the photon emission intensity of the NV ensemble. This device can allow the efficient photon collection even when considering the positional distribution of the NV centers. Our theoretical analysis indicates that the minimum expected sensitivity is 60 fT/

H
z

.

The proposed design can achieve a volume-normalized sensitivity of 0.92 aT/

H
z

c

m

−
3

along with the required power of 7 μW, both of which are superior to those of bulk diamond. The proposed approach offers a promising route towards highly sensitive and energy-efficient magnetometers.
Thermoelectric properties of composition-controlled Fe2TiSi-based full-Heusler thin films
Authors: Kurosaki Yosuke , Yabuuchi Shin , Nishide Akinori , Fukatani Naoto , Hayakawa Jun
Published: July 2022

Fe2TiSi full-Heusler thin films were synthesized with a homogeneous single-phase structure and the composition was controlled in a wide range by deposition techniques. By detailed tuning of the film composition, the Seebeck coefficient reached −184 μV K−1, which is almost the maximum for the full-Heusler alloys, with a power factor of 3.9 mW K−2 m−1. The thermal conductivity was 3.5 W K−1 m−1 and first-principles calculations clarified that this small value may be due to alloy scatterings. Consequently, ZT reached 0.36 at room temperature without any heavy element doping, indicating that Fe2TiSi is one of the promising thermoelectric materials.
Measuring Determinants of Time Deposit in The Commercial Banks in Nepal
Authors: Bista Raghu Bir , Basnet Priyanka
Published: July 2022

Time deposit is one of major source of liquidity of the commercial bank to maintain money supply to the demand of business and household sector. In this context, an interesting query is the determinants of time deposit. This paper measures the determinants of time deposit in the commercial banks of Nepal based on 15 years’ time series data sets from 2000-01 to 2017-18 of the sample commercial banks published by the central bank of Nepal. Using descriptive statistics and multiple regression models as the analytical tools, the paper has found fluctuating trend of liquidity in the commercial banks but inclining trend of external and internal variables including GDP, Deposit, Capital, Size of Bank, remittance and public debt. In this trend, the liquidity of the commercial banks depends significantly on time deposit and remittance inflow.  Besides, the positive trend of time deposit from 1994-95 to 2017-18 has caused the positive trend of total deposit from 1994-95 to 2017-18.  Additionally, the paper has found  that GDP per capita, US exchange rate, interest rate and the branch of the bank are positively and significantly determinants to the time deposit of the commercial bank but inflation rate is negatively and determinant with significance.  The internal variables are more determinants than the external variables to the time deposits. It is clear that time deposit is a reliable and long-term source to main the bank liquidity of the commercial bank for their financial stability and performance depends on more the internal variables than the external variables. Therefore, the commercial bank should reform as mentioned in the monetary policy and money market dynamics to improve the competitiveness and smartness of bank policy including interest rate policy and branch of the commercial banks for effective mobilization of the scattered small resources all over the country for higher rate of capital formation, investment, and economic growth
Analysis of the Effect of Credit Expansion, Operational Efficiency Rate, Lending Interest Rate, NPL of the Previous Period and Capital Adequacy Ratio (CAR) on Non-Performing Loans Based on the Generalized Method of Moment
Authors: Dinah Purnamasari  , Fatchan Achyani
Published: July 2022

This study aims to determine the effect of credit expansion, operational efficiency, lending interest rate, NPL in the previous period and Capital Adequacy Ratio (CAR) on Non-Performing Loans (NPL). This type of research was quantitative and used secondary data from annual reports. This study used a sample of 20 conventional commercial banks registered on the IDX in 2017-2019 with sample determination using the purposive sampling method. The technique for analyzing data in this study used the Generalized Method of Moment (GMM) with data processing using the help of the Eviews 9 application. Based on the Generalized Method of Moment (GMM) analysis, it was obtained that credit expansion as measured by loan to deposit ratio and lending interest rate did not significantly affect non-performing loans. The level of operational efficiency as measured by Operating Expenses on Operating Income (BOPO), NPL of the previous period, and Capital Adequacy Ratio (CAR) significantly affected non-performing loans.
The Effect of the 7P Marketing Mix and Service Quality on Customer Satisfaction
Authors: Pramesty Duwi Putri , Sapar S. , Aqsa Muhammad
Published: July 2022

This study aims to describe and analyze the marketing mix and service quality on customer satisfaction at BRI Palopo Branch. The research sample was taken using the Simple Random Sampling Technique. Data analysis used variant-based structural equation modeling (VB SEM) with the help of Smart PLS software version 3.3. The results of this study indicate that the marketing mix has a significant effect on customer satisfaction of 0.619 units with a t count value: 8,400> t table 1,666 with a P-value of 0.000 <0.05. Service quality has no significant effect on customer satisfaction of 0.103 units with a t-value: 0.632 0.05. The joint influence of the marketing mix (X1) and service quality (X2) on customer satisfaction (Y) is 40.6 percent, while 59.4 percent is influenced by other variables not observed in this study.
Far fare qualcosa a qualcuno o da qualcuno? Quando il causativo causa dubbi
Authors: De Santis Cristiana
Published: July 2022

Alcune domande giunte in redazione chiedono se, con la perifrasi causativa del tipo fare + verbo transitivo all’infinito, sia più corretto introdurre l’esecutore dell’azione con la preposizione a o con la preposizione da.
Domain Adaptation in Predicting Turbocharger Failures Using Vehicle’s Sensor Measurements
Authors: Rahat Mahmoud , Mashhadi Peyman Sheikholharam , Nowaczyk Sławomir , Rognvaldsson Thorsteinn , Taheri Atabak , Abbasi Ataollah
Published: July 2022

The discrepancy in the distribution of source and target domains is usually referred to as a domain shift. It is one of the reasons for the inferior performance of machine learning solutions at deployment. We illustrate that the domain shift issue is pertinent to the readings of the vehicles’ operational sensors. This is due to the fact that these measurements are collected over a period of time and are susceptible to various changes that happen in the meantime. Examples of these changes are usage pattern variations, aging of the vehicles, seasonal shifts, and driver changes. However, domain adversarial neural networks (DANN) have shown promising results to reduce the negative impact of the domain shift. The present study investigates domain adaptation (DA) in the predictive maintenance field by estimating the remaining useful life (RUL) of turbochargers. The devices are operating on a fleet of VOLVO trucks, and the information about their services is collected over four years between 2016 and 2019. The input features to the model are a set of bi-weekly collected measurements called logged vehicle data (LVD). The contributions of this paper are two-fold. First, we propose a new approach for detecting domain (covariate) shift using an autoencoder. Second, we adapt domain adversarial neural networks to the specific application of predicting turbocharger failures. Finally, we deploy a recurrent feature extraction layer in the DANN architecture to incorporate temporal aspect of the data. The experimental results demonstrate the superiority of the proposed method over the traditional approach.
Tool Compatibility Index: Indicator Enables Improved Tool Selection for Well Construction
Authors: Kang Jinlong , Varnier Christophe , Mosallam Ahmed , Zerhouni Noureddine , Youssef Fares Ben , Shen Nannan
Published: July 2022

In the area of well construction, the tool reliability and the field environment are two contributing factors that influence drilling job efficiency and success. Either using high specification tools in low-risk environmental or applying tools of low reliability in harsh environments is inadvisable. Thus, how to select a suitable tool fitting the environment of an approaching drilling job is of great significance for tool planning. However, today, the tool selection decision is not optimized because it is often based on partial data availability and understanding.
This paper presents an indicator called tool compatibility index, which can support improved tool selection decision making. This index takes part reliability, part criticality, and field environment into consideration, and gives a score indicating the compatibility of the tool to a specific environment. Moreover, the tool compatibility index is computed based on a weighted average method, which is computation simple and can be easily deployed. This work is part of a long-term project aiming to construct a risk-based decision advisor for drilling and measurement tools.
Comparative Study of Health Monitoring Sensors based on Prognostic Performance
Authors: Park Hyung Jun , Kim Nam Ho , Choi Joo-Ho
Published: July 2022

In the safety critical systems such as industrial plants or aircraft, failure occurs inevitably during the operation, and it is important to prevent this while maintaining high availability. Therefore, a lot of efforts are being directed toward developing advanced prognostics algorithms and sensing techniques as an enabler for predictive maintenance. The key for reliable and accurate prediction not only relies on the prognostics algorithms but also based on the collection of sensor data. However, there is not much in-dept studies toward evaluating the varying sensing techniques based on the prediction performance and inspection scheduling. It would be more reasonable for practitioner to select different cost of sensors based on the sensors’ contribution on reducing the cost on unnecessary inspection or measurement while maintaining its prognosis performance. Thus, the authors try to thoroughly evaluate the cost-effectiveness of the different sensor with respect to sensor resistance to noise. The simulation is conducted to analyze the prediction performance with varying measurement interval and different level of noise during degradation. Then real run-to-fail (RTF) dataset acquired from two different sensors are analyzed to design optimal measurement system for predictive maintenance.
Failures Mapping for Aircraft Electrical Actuation System Health Management
Authors: Wang Chengwei , Fan Ip-Shing , King Stephen
Published: July 2022

This paper presents the different types of failure that may occur in flight control electrical actuation systems. Within an aircraft, actuation systems are essential to deliver physical actions. Large actuators operate the landing gears and small actuators adjust passenger seats. As developing, aircraft systems have become more electrical to reduce the weight and complexity of hydraulic circuits, which could improve fuel efficiency and lower NOx emissions. Electrical Actuation (EA) are one of those newly electrified systems. It can be categorized into two types, Electro-Hydraulic Actuation (EHA) and Electro-Mechanical Actuation (EMA) systems. Emerging electric and hydrogen fuel aircraft will rely on all-electric actuation. While electrical actuation seems simpler than hydraulic at the systems level, the subsystems and components are more varied and complex. The aim of the overall project is to develop a highly representative Digital Twin (DT) for predictive maintenance of electrical flight control systems. A comprehensive understanding of actuation system failure characteristics is fundamental for effective design and maintenance. This research focuses on the flight control systems including the ailerons, rudders, flaps, spoilers, and related systems. The study uses the Cranfield University Boeing 737 as the basis to elaborate the different types of actuators in the flight control system. The Aircraft Maintenance Manual (AMM) provides a baseline for current maintenance practices, effort, and costs. Equivalent EHA and EMA to replace the 737 systems are evaluated. In this paper, the components and their failure characteristics are elaborated in a matrix. The approach to model these characteristics in DT for aircraft flight control system health management is discussed. This paper contributes to the design, operation and support of aircraft systems.
Physics-informed Lightweight Temporal Convolution Networks for Fault Prognostics Associated to Bearing Stiffness Degradation
Authors: Deng Weikun , Nguyen Khanh T. P. , Gogu Christian , Morio Jérôme , Medjaher Kamal
Published: July 2022

This paper proposes hybrid methods using physics-informed (PI) lightweight Temporal Convolution Neural Network (PITCN) for bearings’ remaining useful life (RUL) prediction under stiffness degradation. It includes three PI hybrid models: a) PI Feature model (PIFM) — constructing physics-informed health indicator (PIHI) to augment the feature space, b) PI Layer model (PILM)—encoding the physics governing equations in a hidden layer, and c) PI Layer Based Loss model (PILLM)—designing PI conflict loss, taking into account the difference before and after integration of the physics input-output relations involved module to the loss function. We simulated 200 different bearing stiffness degradations, using their discrete monitored vibration signals to verify the effectiveness of the proposed method. We also investigate their inference process through feature heat map analysis to interpret how the models melt physics knowledge to assist in capturing the degradation trend. The physics knowledge considered in this paper is the dynamic relationship between vibration amplitude and stiffness in a damped forced vibration model. The results show that all three PITCN models effectively capture degradation-related trend information and perform better than the vanilla lightweight TCN. Furthermore, the visualization of the feature channels highlights the important role of physics information in model training. Channels containing physics information demonstrate higher correlation with results as they significantly dominate the heat map compared to other channels.
Estudo Bibliométrico sobre a pesquisa em Inteligência Artificial no Brasil
Authors: Castro Groenner Luciana , Innocentini Lopes de Faria Leandro , César Perissini Rodrigo , De Souza Gracioso Luciana
Published: July 2022

A produção de fontes de dados tem aumentado nos últimos anos e operacionalizar o seu tratamento, recuperação e uso torna-se um desafio e um diferencial estratégico para os países que detém este domínio. O conhecimento sobre a Inteligência Artificial (IA) tem sido crucial para o processamento e uso dos dados, sendo considerado decisivo para o desenvolvimento econômico e social. Este trabalho teve como objetivo fazer um levantamento sobre a pesquisa em IA no Brasil. Foi elaborada uma expressão de busca abrangente e foram obtidos artigos relacionados no período 2011-2020 na base Web of Science. A partir de métodos bibliométricos, os registros encontrados foram analisados nos softwares VantagePoint, VOSViewer e Excel. Foi realizada uma análise a respeito da participação da pesquisa brasileira em relação ao mundo, das principais instituições de pesquisa em IA no país, dos principais temas de pesquisa e dos autores mais atuantes. Foram construídas redes de coocorrência de palavras-chave, de colaboração entre instituições e entre autores. Constatou-se que o Brasil possui uma participação periférica em relação a publicações, mas em crescimento e que as instituições públicas possuem um papel fundamental nesta produção apesar de discrepâncias regionais, o que poderia auxiliar no desenvolvimento de políticas públicas de inclusão tecnológica.
Growth Strategy Analysis Of Merger Pt. Bank Cimb Niaga Tbk With Lippo Bank
Authors: Hardiyanto Purnawan , Marlitta Stefia Cheryl
Published: July 2022

Introduction: PT. Bank CIMB Niaga Tbk. is a bank which was founded on September 26, 1955 and is the 5th largest bank in Indonesia based on asset value. The initial purpose of establishing this bank is to build values and professionalism, especially in the banking sector. Method: To achieve this goal, research was carried out with using pure quantitative research and then to process the data used descriptive quantitative research. Secondary data sources in this study from the internet or research from another author. Results: The main reason for the merger between the two banks is due to the rules applied by Bank Indonesia regarding the single presence policy. Rule It states that a party is only allowed to be the owner of shares controllers on one bank only. When any party is affected by the rule, then given three options for restructuring, including: merger or acquisition, transfer shares and the formation of a holding company. Changes due to the merger can have an effect on changes in performance. Performance need evaluated regularly because it is very important to maintain company productivity. Conclusion: From the calculation data above, it can be concluded that the merger process is not always bring positive results. This can be seen from the significant decrease in net profit margin and net income total assets. Many things caused the decline in both parts. One of them occurs due to an increase in operating costs which was delegated to Bank CIMB Niaga after the merger. This condition is due to the addition of the number of ATM machines and the development of technological systems that applied to some access and service features.