bluuebunny/crossref_metadata_2025 huggingface dataset:
Local measures of entanglement in black holes and CFTs
Authors: Rolph Andrew
Published: March 2022

We study the structure and dynamics of entanglement in CFTs and black
holes. We use a local entanglement measure, the entanglement contour,
which is a spatial density function for von Neumann entropy with some
additional properties. The entanglement contour can be calculated in
many 1+1d condensed matter systems and simple models of black hole
evaporation. We calculate the entanglement contour of a state excited by
a splitting quench, and find universal results for the entanglement
contours of low energy non-equilibrium states in 2d CFTs. We also
calculate the contour of a non-gravitational bath coupled to an extremal
AdS_22
black hole, and find that the contour only has finite support within the
bath, due to an island phase transition. The particular entanglement
contour proposal we use quantifies how well the bath’s state can be
reconstructed from its marginals, through its connection to conditional
mutual information, and the vanishing contour is a reflection of the
protection of bulk island regions against erasures of the boundary
state.
The Effect of Corporate Reputation on the Performance of Corporate Organizations in Developing Countries: Evidence from West Africa
Authors: Nwagu Kingsley
Published: March 2022

This study is carried out to understand the effect of corporate reputation on the performance of corporate organizations in developing countries: evidence from West Africa. The population for this study consists of selected listed multinational companies in Nigeria and Ghana. The data was collected using a structured questionnaire and was measured on an interval scale through the research questionnaire. The statistical tool used to analyze the set variables is multiple regression. It involves the collection, collation, analysis, and interpretation of data for this study. It further incorporated ANOVA to show CSR Practices and their impact on the performance of corporate organizations as explained by the independent variables through the coefficient of determination R2. This design is useful and most appropriate in measuring the degree of association between two or more variables. It is also helpful in measuring the effect of independent variables on a dependent variable. As predicted, the study proves that corporate social responsibility practice can be integrated into corporations’ business strategy for enhanced performance. Rather than just being beneficial to society, corporate social responsibility can be the value-added opportunity for corporations that engages in responsible actions. The research adds to the existing literature on corporate social responsibility practices and their impact on corporate performance.
Opportunities and Constraints within the Agribusiness Industry in the Emerging Market of Ghana
Authors: Asante Richard
Published: March 2022

The purpose of the study is to conduct an empirical investigation into the important role of technology in a value-driven business process design for an emerging market. Emerging markets are characterized by low GDP because of low economic activities. However, it is full of business opportunities within its environments for prospective businesses or existing small business which wants to scale up or globalize. Moreover, many business constraints exist some are poor technological infrastructure, institutional voids, bribery and corruption, bureaucracy, and poorly trained human capital. There was a critical examination of extant studies by several scholars and researchers related to the objective of the study. The main focus of the review is to establish strong conceptual, theoretical, and empirical support for this study. These included segments that dealt with the conceptual framework review of competitive advantage and theoretical reviews of the Network Theory. Structured as the third segment is the empirical review. This entails an in-depth review of extant studies related to the three-pronged objectives, with the aim of either rejecting or accepting the underlying framework in such studies. Thematic analysis was employed for analysing the primary data collected via focus group discussion plus in-depth interviews. An in-depth examination of the responses of participants revealed that though the majority (19) of the participants agreed that emerging market has several potential and benefits, yet they indicated the existence of certain constraints mitigating increased investment in agribusiness in Ghana, as demonstrated in the excerpt.
Antibacterial activity of plant essential oils obtained from Satureja species against Xanthomonas phaseoli pv. phaseoli and Xanthomonas citri subsp. fuscans
Authors: DÖNMEZ Mesude Figen , UYSAL ŞAHİN Badel , USANMAZ BOZHÜYÜK Ayşe
Published: March 2022

In this study, the antibacterial effects of essential oils obtained from different Satureja species (Satureja cuneifolia Ten., Satureja spicigera (C. Koch) Boiss., Satureja thymbra L., Satureja hortensis L. and Satureja cilicica P.H. Davis) against Xanthomonas phaseoli pv. phaseoli (Smith) Vauterin and Xanthomonas citri subsp. fuscans (Burkholder) Starr & Burkholder, which cause common leaf blight in bean plant, were tested. Essential oils were found to significantly inhibit the growth of bacterial strains of both disease agents in vitro, and the lowest concentrations that prevent bacterial growth were determined for both pathogens. The effects of essential oil applications on seed germination, number of infected cotyledons and disease severity were also evaluated. It was determined that essential oils of S. cuneifolia and S. spicigera has no negative effects on seed germination while essential oils of S. hortensis, S. thymbra and S. cilicica caused a little decrease in seed germination compared to the control. As a result of S. cuneifolia + pathogen and S. spicigera + pathogen applications, no infected cotyledons were detected, and it was determined that the disease development caused by two pathogens was prevented by 100%.
Estudio de la vida real sobre el modelado numérico de las arcadas temporales superiores e inferiores en imágenes de fondo de retina
Authors: Rodríguez-Villalobos Ángel Jonathan , Alvarado-Carrillo Dora Elisa , Cruz-Aceves Iván , Castellón-Lomelí Chrystian Irán , López-Montero Luis Miguel , Hernández-González Martha Alicia , Giacinti David Jaime
Published: March 2022

Introducción: La alta prevalencia de Diabetes Mellitus tipo 2 en México ha posicionado a la retinopatía diabética como la principal causa de ceguera en adultos en edad productiva en México. Por ello, la detección oportuna de este padecimiento es una tarea prioritaria para el sistema público de salud. En el presente artículo se estudia el desempeño de un nuevo algoritmo para la determinación de la forma de la arcada temporal mayor de la retina, mediante el uso de técnicas de segmentación de imágenes y modelado numérico de curvas.   
Método: La metodología propuesta emplea Filtros Gaussianos de Correspondencia que realzan la geometría de los vasos sanguíneos. Posteriormente, la estructura vascular es segmentada mediante la umbralización global de la imagen realzada. Dicha segmentación es utilizada como entrada para construir un modelo numérico de las arcadas temporales superior en inferior, utilizando funciones Spline.  
Resultados: La evaluación de desempeño se realizó utilizando 136 imágenes de  pixeles. El algoritmo de segmentación automática de venas de la retina mediante el método GMF obtuvo un valor de Accuracy de 0.9852; el algoritmo de modelado numérico dio un resultado de 6.01 pixeles en la métrica de la distancia media al punto más cercano (MDCP). Otro estudio previo reportó 12.33 pixeles. Con respecto al tiempo, se reportó un tiempo promedio de 10.65 segundos por imagen.  
Discusión: El método propuesto fue capaz de realizar eficientemente el modelado numérico de las arcadas temporales en imágenes de fondo de ojo. Los resultados demuestran que este método es una herramienta computacional útil para el diagnóstico de alteraciones en la anatomía del ojo.
Photo-illuminated Glutathione Inactivates Alpha-2-macroglobulin: Spectroscopic and Thermodynamic Studies
Authors: Ali Syed Saqib , Ahsan Haseeb , Ansari Sana , Abdullah Khan M , Khan Fahim Halim
Published: March 2022

Background: Glutathione (GSH) is a principle thiol-containing tripeptide (cysteine, glutamic acid and glycine) antioxidant against free radicals and other harmful oxidants in cellular defence. The alpha-2-macroglobulin (α2M) is large tetrameric zinc-binding glycoprotein which inhibits proteinases regardless of their specificity and catalytic mechanism.Materials and Methods: The interaction of GSH was analyzed with α2M including the structural and functional alterations in α2M using various biochemical and biophysical methods. UV-visible and fluorescence spectroscopy were used to study the binding of α2M with GSH and Fourier transform infrared (FT-IR) spectroscopy was explored to study the structural change induced in α2M.Results: The results suggest that exposure of α2M to GSH decreases the antiproteolytic potential as suggested by the amidase assay. The UV-spectroscopic study showed the formation of α2M-GSH complex and fluorescence analysis showed significant quenching in fluorescence intensity of α2M suggesting GSH binding and structural alteration in the protein. FT-IR spectroscopy was explored to study the structural change induced in α2M which suggest that the secondary structure of α2M changes upon complex formation.Conclusion: Our studies show that interaction of α2M with photoilluminated GSH results in functional and conformational changes of the protein.Keywords: glutathione, GSH, alpha-2-macroglobulin, photo-illumination, ITC, FTIR
Neutrophil Extracellular Traps and Its Correlation with Several Pathological Conditions: Prosperities and Deleterious Implications
Authors: Liana Phey , Murti Krisna , Hafy Zen , Liberty Iche Andriyani , Umar Tungki Pratama
Published: March 2022

Neutrophil extracellular traps (NETs) are immune components found in a variety of pathological states. It has been shown to have either beneficial or harmful implications, depending on how it is controlled and has been particularly observed in three major scenarios: infection, autoimmune disease, and cancer. In this article, we compiled some of the roles of NETs in pathological conditions, as well as the benefits of targeting them for improved patient outcomes. The role of NETs were primarily positive in infectious disease, whether caused by bacteria, virus, or fungal infection. In non-infectious inflammatory scenarios, on the other hand, it's the complete opposite, with the effects being mainly deleterious and even worse than the original disease states. Targeting NETs directly or indirectly may help to prevent complications and improve patient outcomes. A plethora of compounds, including immunomodulators, anti-thrombosis, nicotinamide adenine dinucleotide phosphate (NADPH)/reactive oxygen species (ROS) inhibitors, nuclease, and other compounds, may be used to accomplish the therapeutic goals.
Amazon Rainforest: A Natural Source for New Therapeutic Alternatives
against Neglected Tropical Diseases
Authors: da Silva Santos Soraya , Silva João Vitor , Boniface Pone Kamdem , Giarolla Jeanine
Published: March 2022

The Amazon rainforest has wide and unique biodiversity, which is an important source of
natural productsfor the development of drugs. Neglected tropical diseases (NTDs) represent a major
health problem as they affect over 1 billion people, especially vulnerable populations living in tropical
and subtropical regions. Currently available drugs are generally inadequate for the majority of these
diseases, thus, there is an urgent need for new treatments. The present review aims to summarize upto-
date and comprehensive information on the efficacy of the Amazon plants, in treating certainneglected
tropical diseases. According to the literature information, several compounds (phenolics, alkaloids,
terpenoids and steroids, among others) which were isolated from plants of the Amazon forest
showed in vtro activity against Leishmania sp., Trypanosoma cruzi, the parasites responsible for
leishmaniasis and Chagas disease, respectively. Moreover, extracts and essential oil from certain
plants were reported to have mosquito repellent and insecticidal activities against Aedes aegypti, the
vector of dengue, and chikungunya. This review demonstrated that the Amazonian rainforest is endowed
with pharmacologically active plants which can be used as a starting point for the development
of new drugs against NTDs, such as leishmaniasis, Chagas disease, dengue, and chikungunya.
PENGARUH ROGESAN TERHADAP KEANEKARAGAMAN MUSUH ALAMI PADA PERTANAMAN TEBU
Authors: Septiyawati Rizky , Rahardjo Bambang Tri
Published: March 2022

Penelitian ini bertujuan untuk mengetahui keanekaragaman musuh alami pada tanaman tebu yang dilakukan rogesan daun dan yang tidak dilakukan rogesan. Penelitian ini dilaksanakan pada bulan Agustus – Oktober 2020 pada lahan tanaman tebu di Balai Penelitian Tanaman Pemanis dan Serat (Balittas) yang terletak di Jalan Raya Karangploso Km.4, Kepuh Utara, Kepuharjo, Kec. Karangploso, Malang. Pengamatan musuh alami dilakukan dengan metode yellow sticky trap dan hasilnya dianalisis menggunakan uji T, kemudian dilakukan perhitungan Indeks keragaman (H’), Indeks Kekayaan Jenis (R), Indeks Kemerataan Jenis (E’) dan Indeks Dominansi (D). Hasil penelitian didapatkan sebanyak 10 jenis musuh alami pada lahan pengamatan rogesan dan 7 jenis musuh alami pada lahan non rogesan. Uji T menunjukkan tidak ada perbedaan yang signifikan antara jumlah populasi musuh alami yang ditemukan di kedua lahan pengamatan. Nilai H' dan R pada lahan pengamatan rogesan dan non rogesan berada pada kategori sedang. Nilai E memiliki kategori tinggi, baik pada lahan pengamatan rogesan maupun non rogesan. Pada saat yang sama, nilai D pada kedua sistem tidak menunjukkan adanya dominasi.
PENGARUH EKSTRAK DAUN SIRIH MERAH (Piper crocatum Linn.) TERHADAP MORTALITAS DAN REPELENSI Riptortus linearis F. (HEMIPTERA : ALYDIDAE) SECARA IN VIVO
Authors: Kresnadi Danang Wahyu , Rachmawati Rina
Published: March 2022

Penelitian ini bertujuan untuk mengetahui potensi ekstrak daun sirih merah (Piper crocatum Linn) terhadap mortalitas, malformasi, dan repelensi Riptortus linearis. Penelitian dilakukan di Laboratorium Hama Tumbuhan dan Laboratorium Toksikologi Jurusan Hama dan Penyakit Tumbuhan, Fakultas Pertanian, Universitas Brawijaya. Persiapan penelitian terdiri dari perbanyakan serangga uji kepik polong R. linearis dan pembuatan ekstrak daun sirih merah. Penelitian dilakukan dengan menguji ekstrak daun sirih merah pada konsentrasi 1000 ppm, 2000 ppm, 3000 ppm, 4000 ppm, dan 5000 ppm yang diulang sebanyak 4 kali. Uji secara in vivo dilakukan dengan menyemprotkan ekstrak daun sirih merah pada R.linearis dalam sangkar perlakuan. Serangga uji yang masih hidup setelah aplikasi diamati hingga imago. Hasil pengamatan dianalisis menggunakan ANOVA dan uji lanjut DMRT pada taraf kesalahan 5%. LC50 dan LC90 diuji menggunakan aplikasi Hsin Chi. Hasil penelitian menunjukkan bahwa ekstrak daun sirih merah efektif untuk mematikan, menyebabkan abnormalitas, dan bersifat repelen terhadap R. linearis. Nilai LC50 untuk EDSM adalah 2200ppm. Hasil LC90 adalah 6627 ppm yang digunakan dalam skala lapangan. Nilai LT50 untuk menghasilkan mortalitas 50% adalah 26.08 jam. Malformasi berupa tubuh yang membesar dan bercak-bercak hitam. EDSM memiliki sifat penolak yang kuat, tetapi setelah 24 jam, hal tersebut menurun.
Cytokine Response of CD4+ T-Lymphocytes with Red Rose (Rosa Rosaceae – Pierre de Ronsard) Extracts by in Vitro Evaluation
Authors: Arokiaraj Mark Christopher , Menesson Eric
Published: March 2022

Background. Red rose extract is known to have anti-inflammatory and immune-modulation effects. In this study, the red rose extract was tested on CD4+T lymphocytes in vitro, and cytokine response was evaluated.

Materials and Methods. The red rose (Rosa Rosaceae - Pierre de Ronsard) extract used in this study was prepared and stored at -20° C until use. CD4+T-cells were seeded in 96-well plates at 313,500 cells/well in 100μ l cell culture medium in duplicate. One-half of the wells were used for biomarker screening in the culture medium, and the other half was used for cytotoxicity assay. Twenty-four hours after plating, the cells were treated in duplicate with 100μ l of the red rose extract diluted at 0.5%, 0.1%, 0.05%, 0.01% and 0.005% (v/v) in the cell culture medium or with culture medium only as control for 72 hours. Some other wells were allocated for untreated cells, and cells treated with the rose extract at 0.005% for 48-h incubation time.

Results. Several cytokines (GRO; IFN-γ; IL-1α, 6, 10; MCP-1; RANTES; TGF-β1; TIMP 1, 2; Ang1, Ang2; G-CSF; MMP-9; and VEGF R2) were elevated. Except for MMP-9, which had fold changes > 2, other cytokines were minimally elevated at various concentrations and timing of rose extract treatment. None of the mentioned cytokines were less than 0.8-fold after treatment with the rose extract. Cytotoxicity assay revealed insignificant changes in the viability of T-cells.

Conclusions. There was a mild elevation in few inflammatory markers by CD4+ T-lymphocytes after in vitro treatment with the red rose extract (Rosa Rosacea - Pierre De Ronsard). Further in vitro and in vivo studies are required to evaluate the benefits of the red rose extract in immune regulation.
Antenatal Care dan Komplikasi Kehamilan di Provinsi Daerah Istimewa Yogyakarta dan Jawa Barat
Authors: Umniyati Helwiah , Purnamasari Telly , Febriani Esty
Published: March 2022

Latar Belakang: Rendahnya cakupan antenatal care (ANC) dan tingginya komplikasi kehamilan merupakan faktor risiko penting penyebab kematian ibu di Indonesia. RISKESDAS 2010 memperlihatkan komplikasi kehamilan tertinggi di Provinsi D.I. Yogyakarta (13,9%), bila dibandingkan angka nasional (6,5%) dan Jawa Barat (6,9%).Tujuan: Untuk mengetahui faktor-faktor yang berhubungan dengan komplikasi kehamilan di Provinsi Daerah Istimewa Yogyakarta dan Jawa Barat.Metode: Penelitian ini merupakan gabungan dari penelitian kuantitatif dan kualitatif. Penelitian kuantitatif menggunakan data RISKESDAS 2010 sedangkan penelitian kualitatif menggunakan wawancara mendalam dan FGD.Hasil: Analisis regresi cox menunjukkan bahwa menginformasikan gejala komplikasi kehamilan selama kunjungan ANC berhubungan secara signifikan dengan komplikasi kehamilan. Hasil dari penelitian kualitatif menunjukkan bahwa penerapan ANC di D.I. Yogyakarta sangat baik ketika dibandingkan dengan Jawa Barat. Keberhasilan ini tidak terlepas dari dukungan pemerintah dan masyarakat. Tingginya deteksi dini risiko kehamilan oleh masyarakat (157,88%) diduga menjadi penyebab rendahnya AKI di D.I. Yogyakarta.Kesimpulan: Pelaksanaan program KIA di D.I. Yogyakarta sudah sangat baik. Disarankan bahwabidan selalu menginformasikan risiko kehamilan sejak ANC pertama. Hal ini dapat mencegah terjadinya komplikasi kehamilan, terutama di provinsi dengan angka kematian ibu yang tinggi.
Ideologi Gender Dalam Film Soviet ДВЕНАДЦАТЬ МЕСЯЦЕВ ‘Dua Belas Bulan’
Authors: Thera Widyastuti , Utami Annisa Salshabia Nur
Published: March 2022

Fairy tales are often identified with messages to be conveyed to readers, and can also contain certain ideologies. Many studies have analyzed the relations between fairy tales and gender ideology. Therefore, the writer chose the Soviet film entitled Двенадцать месяцев 'Twelve Months' (1972) as the source of research data, because there are additional elements written by Marshak. The purpose of this research is to describe the actant scheme and the characterization in the film, and to analyze whether gender ideology is present in the film, and how the ideology is presented. The approach used is the Greimas' actantial model approach. The method used in this research is qualitative and descriptive analytical methods. The result of this research shows that there are still gender stereotypes in the film, which can be seen from the actantial schemes and the characterization of the characters.
Analisis Berita Pencalonan Gubernur Dan Wakil Gubernur NTT Tahun 2018 Pada Surat Kabar Victory News: Sebuah Kajian Wacana Kritis
Authors: Lagut Fransiskus Rolantus , Tans Feliks , Robot Marselus
Published: March 2022

This study aims to analyze the text, the practice of citizenship and the socio-cultural context in the news text of the election of the governor and vice governor of East Nusa Tenggara in 2018 in the Victory News newspaper. The theory used in this study is Norman Fairclough's critical discourse analysis to analyze texts, the practice of producing and consuming texts, and socio-cultural practices on texts. The method used is descriptive qualitative method. From the data analysis, conclusions can be drawn. First, the VN news text features the 'promise' vocabulary which tends to be used to weaken the pair of candidates for governor-vice-governor besides Viktory-Joss. Transitive sentences tend to be used in the headline of VJ packages while other packages tend to be intransitive sentences. The use of negative sentences and metaphors tends to be used to benefit VJ packages. The news texts used by Victory News tend to be descriptive and argumentative in nature, characterized by the use of meaningful causal conjunctions. Second, Victory News discourse tends to raise news about the campaign, vision and mission, the strength of character and background that supports the Viktory-Joss package. Victory News tends to be political, which means that the interests of the owners of these newspapers are more dominant than balanced reporting. Third, Victory News ideology is positive imaging by highlighting the VJ package so that the public positively evaluates the vision, missions, and actions taken by the package
Management Skills and Learning Strategies among University of Southern Philippines Foundation Graduands
Authors: Pulmones Lucio
Published: March 2022

Graduands in the Philippines are most likely pursuing education while working for their own merit in any workplace like schools, industries, and other companies. At University of Southern Philippines Foundations, graduands who are enrolled in educational management are not only concentrating on their quest for higher education but also for their desire to achieve promotion, stability, and prestige. Two hundred sixty-three (263) respondents answered the questionnaires on management skills and learning strategies and the results made an overall impression that these graduands are always in the loop of good management skills with motivating and communicating having aggregate means of 3.43 and 3.37 respectively with the same interpretation as always. Likewise, the result revealed that these graduands are using different learning strategies with a grand mean of 3.16 interpreted as agree. A significant relationship was established between management skills and learning strategies which rejected the statement of the null hypothesis. The higher the management skills of a graduand the higher and better is his or her learning strategies. It was concluded that though graduands are highly skillful in management, there is a need to improve their learning strategies. Thus, the researcher recommends L.E.A.P. or Learning Enhancement and Practice.
Design of Twist Morphing Mechanism for Horizontal Stabilizer
Authors: Mathew Bilji C , Dutta Prantik , Sahu Sagar K , Kunjir Vasudha , Chaugule Samruddhi
Published: March 2022

Abstract: Mimicking birds to enhance aerodynamic efficiencies of modern day aircrafts is a method that has seen major applications in the aerospace industry. Birds, due to their feathers, muscles and distinct morphologies tend to utilize methods that are otherwise impractical to incorporate in aircrafts due to limitations in terms of structure and materials. Yet, major influences are seen in many aircrafts that are inspired by the aerodynamic features of avian beings. Morphing is a major method that helps aircrafts make changes to their components, such as their wings to adapt or adjust to their varying flight conditions for efficient control and performance. In this paper, a mechanism is designed that aims at using morphing techniques to mimic a bird’s tail. The main purpose of this design is to achieve yaw control and directional stability in absence of a rudder and with the aid of the horizontal stabilizer solely. Keywords: Morphing, yaw stability, compliant mechanism, biomimetics, tail, twist morphing
Pemanfaatan Informasi Covid-19 Di Gampong Beurawe, Banda Aceh
Authors: Hz M. Khalilullah , Nengsih Sri
Published: March 2022

This study aims to analyze the use of Covid-19 information technology in Beurawe Village, Banda Aceh, in the midst of the corona virus pandemic and the results of the study show that the use of information technology has a very important role in people's understanding in order to be able to understand and prevent the spread of Covid-19. The Beurawe Village community must really understand the Covid-19 information conveyed. Understanding alone is not enough if there is no action to break the Covid-19 chain. With the information technology that is currently developing rapidly, including information media and internet networks that can connect the government and the Beurawe village community so that the socialization process to the community can run well and quickly as it should, even though in the midst of the COVID-19 pandemic, which limits activities.
Racial/Ethnic Group Trajectory Differences in Exam Performance Among US Family Medicine Residents
Authors: Wang Ting , O'Neill Thomas R. , Eden Aimee R. , Taylor Melina K. , Newton Warren P. , Morgan Zachary J. , Peterson Lars E.
Published: March 2022

Background and Objectives: Racial/ethnic score disparities on standardized tests are well documented. Such differences on the American Board of Family Medicine (ABFM) certification examination have not been previously reported. If such differences exist, it could be due to differences in knowledge at the beginning of residency or due to variations in the rate of knowledge acquisition during residency. Our objective was to examine the residents’ mean initial scores and score trajectories using the In-Training Examination (ITE) and certification examination.
Methods: A total of 17,275 certification candidates from 2014 to 2019 were included in this study. Annual ITE scores and certification examination scores are reported on the same scale and serve as the outcome. We conducted multilevel longitudinal regression to determine initial knowledge and growth in knowledge acquisition during residency by race/ethnicity categories.
Results: The mean postgraduate year 1 (PGY-1) ITE score was 393.3, with minority residents scoring 16.2 to 36.0 points lower compared to White residents. The mean increase per year in exam performance from PGY-1 ITE to the certification exam was 39.9 points (95% CI, 38.7, 41.1) with additional change among race/ethnicity categories per year of -3.2 to 1.9 points.
Conclusions: This study found that there were initial score disparities across race/ethnicity groups in PGY-1, and these disparities continued at the same rate throughout residency training, suggesting equality in acquisition of knowledge during family medicine residency training but with a persistent gap throughout training.
Effectiveness of Hysteroscopic Myomectomy Compared to Medical Management on Patients’ Quality of Life: A Randomized Clinical Trial
Authors: Tam Maria , Juarez Loudes
Published: March 2022

Objective: To evaluate the quality of life in patients treated for
submucosal leiomyomas after hysteroscopy myomectomy compared to medical
therapy Patients: Patients with symptomatic submucosal leiomyomas from
2014-2017. A total of 69 patients enrolled, with 47 completed.
Interventions: Each patient was randomized to (1) oral contraceptive
pills/progesterone releasing intrauterine device or (2) hysteroscopic
myomectomy using a hysteroscopic tissue removal system. Each patient was
to complete the Uterine Fibroid Symptom and Health-related Quality of
Life (UFS-QOL) questionnaire at baseline, one month, three months, and
greater than or equal to six months after treatment. Measurements and
Main Results: Primary outcome was the health-related quality of life
(HR-QOL), as reflected from UFS-QOL scores. Contrasts were constructed
from a linear mixed-effects model to compare the two treatment groups
for changes from baseline in UFS-QOL scores. UFS-QOL scores were similar
at baseline between the two treatment groups. There was an overall
improvement in all UFS-QOL scores within each group. Higher improvement
scores were noted in the surgical group compared to the medical group
for almost all UFS-QOL scores. At ≥6 months, in comparison to the
medically managed patients, the most considerable score improvements for
the surgical group were reported in HR-QOL concern, activities,
self-consciousness and symptom severity scores having mean change scores
(95% CIs) of 35.3 (22.3 – 48.2), 28.9 (16.3 – 41.5), 28.6 (15.0 –
42.1), and 32.2 (21.5 – 43.0), respectively. Conclusion: Patients with
submucosal leiomyomas who received medical or surgical treatment
reported similar improvement in overall health related quality of life
scores.
Covid-19 complicated with chronic necrotizing pulmonary aspergillosis and aspergilloma progressing to fibrosing aspergillosis: a case report
Authors: Razafindrasoa Zamelina Angela , Ravahatra Kiady , Tiaray Harison Michel , Nandimbiniaina Anjara Mihaja , Andriamahenina Princy Parfait , Razafimpihanina Sonia Marcelle , Andriarimanga Diamondra ombanjanahary , Rakotomizao Jocelyn Robert , Rakotoson Joëlson Lovaniaina , Raharimanana Rondro Nirina
Published: March 2022

Cases of aspergillosis superinfection have been reported as acute
complications of Covid-19. Here we report a case of combined chronic
necrotizing pulmonary aspergillosis, aspergilloma and fibrosing
aspergillosis in a 31-year-old woman with a history of Covid-19. This
unusual association deserves special attention in a secondary
immunocompromised patient after Covid-19.
Examining the Behavior in Public Good Games: An Application of Prisoner’s Dilemma
Authors: Khan Zarlasht , Maud Hadiya , Zubair Mariam , Salman Verda , Nazuk Ayesha
Published: March 2022

Standard belief in economic theory asserts that effective public good provision will always be hindered by the presence of free-riders. Yet in contradiction to this, many collective goods have managed to be effectively provided by large bodies of people working together. This begs the question: how prevalent is free-ridership in reality and how well does theory translate into practice? We have tested this theory by subjecting participants to experimental conditions where the impacts of social pressure have been observed via the formation of groups of four. Results have shown that, though individuals are likely to contribute in our treatment condition; even in the absence of social pressure, individuals will willingly donate around 40% of their endowments. This has allowed us to conclude that, in our experiment, the free rider hypothesis is not supported.
Why Industry 4.0 Adoption is Unavoidable for Sustainable Performance of Organizations?
Authors: Sohail Asghar , Amin Ul Haq Mirza
Published: March 2022

The purpose of this research is to endorse the importance of the fourth industrial revolution and its adoption in terms of organizational performance. In this study, we have discussed that the adoption of Industry 4.0 (I4A) parameters can improve production outcomes and reduce operational wastes. In order to comprehend whether Industry 4.0 parameters are feasible to accomplish, organizations should get valuable guidelines by differentiating the production outcomes vide pre and post-technological implementation. It has been revealed that organizations with industry 4.0 lean and sustainable practices have achieved more substantial upshots in social, economic, operational, and environmental performance i.e. overall Organizational Performance (OP). Likewise, prevailing global trends have indicated that innovative performance and adoption of Industry 4.0 technologies have become ‘unavoidable’ in the business arena, thus providing the sign to companies to start embracing developments related to process optimization in order to sustain or even reinforce the competitiveness. Conclusively, organizations should not only emphasize process automation but also introduce smart and credible systems for better outcomes
Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis
Authors: Solomon Michal , Greenberger Shoshana , Milner Maya , Pavlotzky Felix , Barzilai Aviv , Schwartz Eli , Hadayer Noa , Baum Sharon
Published: March 2022

The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis. This retrospective study was performed in 114 patients. Systemic treatments included liposomal amphotericin B and sodium stibogluconate. All patients underwent systemic treatment for L. tropica cutaneous leishmaniasis. Favourable treatment responses were recorded in 72.5% and 70.2% of the patients in the liposomal amphotericin B and sodium stibogluconate groups, respectively; 25.3% and 46% of those in the liposomal amphotericin B and sodium stibogluconate groups respectively, experienced at least one adverse effect. Lesions in cartilaginous areas were associated with higher treatment failure. Prior topical or systemic treatment increased the chance of future systemic treatment success. Liposomal amphotericin B was associated with a shorter intravenous treatment duration and better safety profile. Thus, liposomal amphotericin B is the treatment of choice for L. tropica cutaneous leishmaniasis.
Ecthyma Gangrenosum in 5-Month-Old Long-Term Ventilated Infant: A Case Report
Authors: J Itani
Published: March 2022

Rationale: Ecthyma gangrenosum (EG) is an aggressive cutaneous disease caused by local or systemic infection with Pseudomonas aeruginosa. EG is characterized by cutaneous manifestations ranging from nodule and papule to necrotic ulceration with surrounding erythema, especially with black eschar or central crust. EG presents with characteristic skin lesions which is important to establish diagnosis of sepsis caused by P aeruginosa, a serious condition that can be treated efficiently if diagnosed early. Patient concerns: A 5-month-old male infant, case of Severe HIE, Ventilatory dependent with Tracheostomy, NGT feeding, Epilepsy and dystonia admitted to Cambridge Medical and rehabilitation Center (CMRC)–AUH -UAE. Developed characteristic skin lesions of EG and developed sepsis. Diagnoses: Ecthyma gangrenosum and sepsis caused by Pseudomonas aeruginosa. Interventions: Meropenem was used in combination with Vancomycin at first and then continued only with Meropenem. Outcomes: Cure. Lessons: Early recognition of EG plays an important role in providing appropriate empiric antibiotic treatment at early stage and improves the prognosis. Close clinical follow up on skin lesion evolution is an alternative to possible invasive management.
Merkel Cell Carcinoma: Diagnostic and Therapeutic Workup from a Head and Neck Surgeon Perspective
Authors: BM Erovic
Published: March 2022

Merkel cell carcinomas (MCC) are highly aggressive skin malignancies, resulting in death of more than one-third of patients with increasing incidences over the past decades. The carcinogenesis is associated with Merkel cell polyomavirus (MCPyV) infection and/or ultraviolet-induced DNA mutations. Diagnosis is made by histology and specific immunohistochemical stains. Among them, cytokeratin 20 (CK20) expression represents indeed the most important marker. The treatment consists of either wide local excision to achieve clear margins accompanied by nodal dissection or radiation therapy. In advanced stage diseases, survival rates still remain low, but immunotherapy with PD-L1 and PD-1 inhibitors are promising. The increasing incidence, the rapidly and aggressive clinical course as well as some unsolved diagnostic and therapeutic challenges underline the need for a better understanding of MCC. Therefore, the aim of this short review was to present an overview of the current literature regarding diagnosis and treatment of MCC patients.
Legal Instruments for Control of Sustainable Tourism Investment in Bali from Citizenship Ecological Perspective
Authors: Adnyani Ni Ketut Sari
Published: March 2022

Penggunaan tata ruang seringkali mengabaikan konsep Asta Kosala-Kosali. Investasi pariwisata di Bali dalam pemanfaatan ruang dan lingkungan ditandai dengan berbagai bentuk pelanggaran pemanfaatan ruang yang banyak terjadi di beberapa daerah, terutama Badung, Gianyar, Singaraja, Tabanan, Klungkung, Karangasem dan Kota Denpasar. Bentuk pelanggaran radius jurang, pantai, sungai dan danau yang berdampak negatif bagi lingkungan. Penelitian ini bertujuan untuk mengungkap problematika fungsi dari lemahnya fungsi peraturan perundang-undangan dalam pengendalian investasi pariwisata. Penelitian ini merupakan penelitian hukum normatif dengan pendekatan perundang-undangan dan pendekatan hukum berorientasi kebijakan. Jenis penelitian ini adalah yuridis normatif. Informan ditentukan secara purposive. Pengambilan data di Provinsi Bali dengan jumlah informan 18 orang di 8 kabupaten dan 1 kotamadya dengan sampel desa wisata Tanah Lot, Kabupaten Tabanan, Lovina, Kabupaten Buleleng, Amed di Kabupaten Karangasem, dan hutan mangrove di komando kecamatan Denpasar. Hasil analisis bahan hukum disajikan dengan menggunakan teknik analisis deskriptif. Hasil analisis peneliti terhadap sejumlah objek wisata di Provinsi Bali, seperti wisata Tanah Lot, Lovina, Amed, dan mangrove di Denpasar, menunjukkan bahwa pengembangan pariwisata di beberapa daerah di Bali belum mendapat perhatian. analisis mengenai dampak lingkungan (AMDAL) dan mengabaikan konsep Asta sebagai isi instrumen hukum pengendalian investasi sebagai alternatif perwujudan investasi pariwisata yang berkelanjutan.
Socialization of The Google Docs Usage as a File Collaboration Media During Pandemic
Authors: Fajri Misbahul , Priambodo Bagus , Jumaryadi Yuwan
Published: March 2022

Teknologi yang berkembang pesat saat ini memudahkan manusia dalam melakukan pekerjaannya. Perkembangan teknologi informasi yang berkembang pesat menuntut kemampuan warga untuk dapat beradaptasi dengan perkembangan teknologi yang ada. Seseorang dapat melakukan pekerjaannya dari jarak jauh di rumah, tanpa harus datang ke kantor. Agar proses kerja jarak jauh menjadi lebih lancar, orang tersebut harus terlebih dahulu memahami penggunaan teknologi untuk membantu pekerjaannya. Di masa pandemi, pelatihan penggunaan Google Suite (Google Docs) sangat bermanfaat sehingga nantinya jika ada proses data yang harus di-share akan mempermudah proses update data. Kegiatan pengabdian masyarakat ini bertujuan untuk berbagi ilmu agar warga di Desa Meruya Utara dapat menambah pengetahuan dan meningkatkan kemampuannya dengan memanfaatkan teknologi informasi dan komunikasi dengan memperkenalkan Google Docs sebagai media kolaborasi file di masa pandemi. Metode yang digunakan adalah metode sosialisasi praktis dengan memberikan pelatihan Google Docs sehingga diharapkan melalui sosialisasi ini pemahaman dan penguasaan penggunaan Google Docs bagi warga di Meruya Utara dapat tercapai. Hasil kegiatan pengabdian masyarakat yang dilakukan menunjukkan bahwa para peserta kegiatan pengabdian masyarakat dapat memahami pentingnya penggunaan Google Docs di masa pandemi.
Youtube for Teaching Listening in English Language: the Benefits in Experts’ Views
Authors: Yasa Bayu Hendra
Published: March 2022

Beberapa siswa Indonesia mengungkapkan bahwa mereka menemukan kesulitan dalam belajar mendengarkan karena mendengarkan hanya dapat dilakukan dalam satu kesempatan tanpa dapat mengulanginya. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh penggunaan video YouTube dalam pengajaran mendengarkan dengan mengevaluasi hasil penelitian sebelumnya dalam temuan dan memeriksa beberapa referensi tertulis yang meliputi teori, keyakinan, temuan penelitian, dan sumber lain yang terkait dengan dampak video YouTube. Penelitian ini menggunakan penelitian kepustakaan sebagai teknik pengumpulan data yang menggunakan sumber dari beberapa dokumentasi. Sumber data diperoleh dari sumber tertulis yang terkait dengan penggunaan video YouTube dalam pengajaran mendengarkan. Hasil penelitian menunjukkan jumlah siswa terbanyak (54 siswa) yang mengaku YouTube hanya untuk hiburan, sedangkan tiga siswa mengakses YouTube terkait materi pendidikan lainnya. Dapat disimpulkan bahwa YouTube adalah situs web tempat para guru atau siswa dapat mengambil bahan ajar otentik, video hiburan, dan dapat digunakan sebagai sumber belajar. Siswa tampak tertarik dengan kegiatan belajar saat menggunakan YouTube karena video YouTube menarik perhatian mereka. Siswa dapat memperoleh wawasan yang lebih baik tentang pelajaran mata pelajaran dengan bantuan video YouTube yang memberikan dukungan visual.
Improve Students’ English Vocabulary Skills With Flashcard Media
Authors: Fitriana Rizkia Odie , Hadi Muhamad Sofian , Izzah Lidiyatul
Published: March 2022

Pengembangan bahasa inggris di sekolah maupun di luar sekolah sangat penting untuk anak anak. Kemampuan bahasa inggris anak anak berbeda beda karena yang kita ketahui setiap anak pun memiliki karakter yang berbeda beda. untuk meningkatkan kemampuan bahasa inggris di perlukan dorongan motivasi dan media pembelajaran yang bertujuan untuk meningkatkan skill bahasa inggris anak dengan menarik, aktif, dan mudah memahami. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif untuk mencapai hasil dan kesimpulan yang sesuai dengan yang di teliti. Data yang di peroleh berasal dari jurnal – jurnal yang terkait dari artikel ini atau yang membahas tentang meningkatkan skill bahasa inggris dengan media flash card. Hasil yang di dapat dari penelitian terkait peningkatkan skill bahasa inggris dengan media flash card ialah pembelajaran yang mencapai hasil yang maksimal, memudahkan anak anak memahami kosa kata bahasa inggris dengan menarik karena berupa gambar yang di desain semenarik mungkin. Kesimpulan nya adalah bahwasannya media flash card sangat efektif untuk meningkatkan skill bahasa inggris anak di sekolah maupun di luar sekolah dan peningkatan hasil belajar anak bisa di lihat dari lancarnya pengucapan kosa kata bahasa inggris saat penggunaan media flash card.
Exploring the health impacts and inequalities of the new way of working: findings from a cross-sectional study.
Authors: Griffiths Melda Lois , Gray Benjamin J , Kyle Richard G , Davies Alisha R
Published: March 2022

BackgroundEmployment is a wider determinant of health, and one of the most striking societal transformations witnessed during the SARS-CoV-2 (COVID-19) pandemic was the sudden shift to working from home (WFH). Within the COVID-19 recovery and efforts to tackle climate change, having large proportions of the workforce WFH has clear benefits. However, the wider adoption of such measures should account for inequalities in accessing home working, the workforce’s preferences for the future, and crucially, the impact that WFH might have on the workforce’s health.

MethodsA nationally-representative household survey was undertaken across Wales (Public Health Wales’ COVID-19, Employment and Health in Wales study), with cross-sectional data on home-working being collected between November 2020 and January 2021 from 615 employed working-aged adults in Wales (63.7% female, 32.7% aged 50-59). Respondents were asked about their ability to WFH, their perceptions of its impact on their health and their preferences for time spent home-working in future.

FindingsOver 50% were able to WFH, and showed a preference towards home-working to some capacity, with over a third wishing to WFH at least half the time. However, those living in the most deprived areas, in atypical employment, with high wage precarity or with limiting pre-existing conditions were less likely to report being able to WFH. Of those that could WFH, over 40% reported that it worsened their mental well-being and loneliness, and for people in poorer health, home-working negatively impacted their diet, physical activity, smoking and alcohol use. People aged 30 to 39 and those who lived alone were more likely to report wanting to spend some time working in an office/base instead of at home.

ConclusionsThe new way of working introduces new challenges to preserving workforce mental well-being, regulating health behaviours and tackling inequalities. Our findings shine a light on the negative health impacts associated with WFH (particularly for those already in poorer health), highlight how disadvantaged population sub-groups face further inequalities through being less able to WFH, and provide novel observations of the preferred working models of different sub-groups within the population. Hybrid approaches, combining home and work-based employment are preferred and could alleviate the negative health impacts associated with WFH. Addressing inequalities across the workforce to ensure that everyone is as able to participate in this transformative shift in ways of working is key.
Covid-19 Digital health literacy of Sofia University IT students – preliminary results
Authors: Patias Ioannis
Published: March 2022

BackgroundThe SARS-CoV-2019 pandemic and the Coronavirus Disease 2019 (COVID-19) virus, made us use various sources of health information available on different digital platforms on the Internet, thus brought in front side issues related to health literacy (HL). People using digital information platforms not always have the ability to adequate evaluate the acquired health information. Even more IT professionals are often engaged in systems development, where their ability to provide the system with reliable, checked input as for example training data and information is crucial. Namely this makes IT students, as future professionals, health literacy important case for study.

MethodsFor the purpose a Questionnaire developed by Dadaczynski, K., Okan, O. & Rathmann, K. in 2020 as COVID-19 Health Literacy Survey: University Students (COVID-HL Survey), and the respective Scale Documentation under the Public Health Centre Fulda (PHZF) at the Fulda University of Applied Sciences & Interdisciplinary Centre for Health Literacy Research at Bielefeld University, was used. The main goals are to assess digital HL of university students; explore the different digital sources of information students consult when seeking for COVID-19 information; capture student’s future time perspective/worries; and also assess students Sense of Coherence under this health situation.

FindingsMost (roughly above 60%) of respondents indicated that it was easy to search, acquire, evaluate reliability, and determine relevance for health information related to COVID-19, SARS-CoV-2019, and other related topics. Immersive the amount of students (above 85%) that crosscheck acquired health information in both English and Bulgarian languages. As for the various possibilities of how to get information about the coronavirus and related topics on the Internet, the respondents indicate most often they use search engines (e.g. Google, Bing, Yahoo!), followed by official Health portals (for example, the Bulgarian unified information portal, the current news – Ministry of Health, and the Regional Health Inspectorate).

ConclusionsThe preliminary results so far show that most of the students of the current sample reported high HL. May be their ability to crosscheck health information explains their satisfaction regarding to this information. Young people as the students in Sofia University trust modern digital platforms, but also have a high rated opinion for the official heath authorities in the country, including the developed Bulgarian unified information portal, the Ministry of Health, and the Regional Health Inspectorate web pages. The study is still ongoing. More results and discussion should follow the responses acquisition completion.