bluuebunny/crossref_metadata_2025 huggingface dataset:
SYNERGETIC PHILOSOPHY OF HISTORY AND THE PROBLEM OF FREEDOM: METHODOLOGICAL ANALYSIS
Authors: Busov Sergey V.
Published: October 2023

Society is considered by the synergetic philosophy of history as a “dissipative structure”. The author analyses the mechanism of self-organisation of society – social selection – in terms of its factors such as thesaurus, detector and selector (V. Bransky). Freedom is an element of social selection. It manifests itself as a way of human existence. Freedom is directly correlated with the category of accident, but unlike it, it is only a “particular” form of necessity. In contrast to the definition of freedom as a recognised necessity, the definition of freedom as a recognised accident within the framework of regularity carries the unity of motive and action. Mastering the accident factor, a person more deeply comprehends the scope of possibilities presented by a complex system of relationships and patterns, changes his/her future and the future of society.
THE DISPUTE ABOUT THE ROLE AND VALUE OF COMPETITION IN GENERAL EDUCATION: PHILOSOPHICAL ANALYSIS
Authors: Tylik Artem Y.
Published: October 2023

The article examines the current debate about the role and value of competition in general education from the perspective of metatheoretical analysis. It has been established that supporters of the development of competitive relations in general education systems consider competition as an effective mechanism for increasing the efficiency of educational organisations. In this case, ideas are inherited along the line: A. Smith, T. Malthus, C. Darwin, M. Freeman. In turn, opponents of the development of competitive relations in general education systems oppose the concept of “competition” with the concept of “social capital” (P. Bourdieu), largely inheriting the ideas of P. Kropotkin.
THE AESTHETIC AND SENSUAL IN CULTURE: PAINTING EXPERIENCE AND WINE TASTING IN THE CONCEPTION OF CONNOISSEURSHIP OF MAX FRIEDLÄNDER
Authors: Sholomova Tatiana V.
Published: October 2023

The article compares the features of sensory and aesthetic perception using the example of wine tasting and expert judgment about the authorship of a work of art from the standpoint of the philosophy of culture. The comparison belongs to the German art historian and theorist of knowledge M. Friedländer (1867–1958). This comparison might seem more conventionally artistic than able to really explain the specifics of aesthetic perception or reasons for the convergence of such cultural phenomena as wine tasting and artistic style, since taste is the most unreliable and most dependent of our senses, in contrast to vision. But the Belgian art theorist T. Lenain shows how a change in the understanding of a work of art (from a normative idealistic approach to a historicist one), firstly, changes our perception of art (which is now understood as a set of imprinted traces – from the cultural characteristics of the era in which the work was created, to the characteristics of the personality of the artist). Secondly, if a work of art grows as a fruit of a certain style and a certain person, then when we perceive it, we see all the features, all manifestations of this style, and we can judge the authorship – just like a true wine specialist will determine its pedigree in just one sip, true connoisseurs are able to recognise the master’s hand at a glance. Thus, the seemingly exotic comparison of the perception of art with the perception of wine becomes quite justified.
“A PICTURE OF MAN” BY A. I. GALICH AND THE PROBLEM OF A “CONTRACTUAL PERSON”
Authors: Lisitsin Boris B.
Published: October 2023

The article discusses the relevance of the creative heritage of A. I. Galich in connection with the crises occurring within the modern scientific community. Using the example of classical authors and modern scientific publications, the author substantiates the need to clarify the essence of man and to build science and education in accordance with the requirements of anthropological meaningfulness, which implies referring to the field of ontology, epistemology and anthropology.
PERANCANGAN RUMAH SUSUN MAHASISWA UNIVERSITAS TANJUNGPURA DENGAN KONSEP MINIMALIS
Authors: Handayani Nur , Irwin Irwin , Nurhamsyah Muhammad
Published: October 2023

Universities located in the city center and far from district locations and areas. Not a few students who migrate to continue their education to tertiary level. This condition certainly requires the existence of temporary housing for overseas students during their education period. Pontianak City is one of the city centers where there is a university, namely, Tanjungpura University. One of the temporary residences that is still rare is the existence of special student flats. These student flats can assist students in helping with temporary housing. This student flat is designed with a minimalist concept which is currently a trend and is in vogue. The purpose of this design is to design student flats that are comfortable with a room atmosphere, space requirements that suit student needs. With several public facilities such as sports venues, shared open spaces, places to relax, places of worship and places to study. The design of student flats prioritizes building functions and efficient space requirements. In achieving this goal, traditional design methods (black box) which in this method is a design method that is carried out spontaneously. Ideas that come from anywhere and at any time according to the designer's imagination spontaneously. Based on background issues and objectives in the design and through some data analysis carried out resulted in a student flat building design with a minimalist concept with a total of 4 floors with private facilities as well as public facilities.
COWORKING SPACE DI KOTA PONTIANAK DENGAN PENDEKATAN PRINSIP FLEKSIBILITAS DALAM ARSITEKTUR
Authors: Nurhidayati Nurhidayati , Pebriano Valentinus , Muazir Syaiful
Published: October 2023

The freelancer profession in the current era is in great demand by many people. In the world of freelancing, income and place of work are not fixed. Most freelancers have little business capital in leveraging skills and building relationships. In addition, freelancers do not have a limit on working time, but are free to determine where to work. Freelancer activity facilities in Pontianak City do not support convenience. They are active in cafes or coffee shops with a low level of privacy. Freelancers and other creative industry players need a place that is comfortable for their activities, both working, socializing, and collaborating in running their business. They need a container that fits their activities, namely coworking space. Coworking space is a multifunctional workplace that combines various commercial functions, such as offices, meetings, culinary, entertainment, and others. For this reason, it is necessary to design a coworking space in Pontianak City. The purpose of a coworking space is to accommodate various work activities, both individually and in groups, along with their supporting activities. The design method used is flexibility in architecture, including adaptable and universal space. The steps used are looking for problems, identifying, collecting data, analyzing, conveying ideas, selecting ideas, designing products, and evaluating. The expected result is a flexible spatial plan inside and outside the coworking space, adapting to the dynamics of freelancers and other users.
Direct C3-functionalization of indoles with alpha-heteroaryl-substituted methyl alcohols via a metal-free hydrogen autotransfer-type reaction
Authors: Pazur Ethan , Tasker Nikhil , Wipf Peter
Published: October 2023

The transition metal-free Cs2CO3/oxone®-mediated C3-alkylation of indoles proceeds in moderate to high yields with a variety of C4–C7 functionalized indoles and is applicable to 2-, 3- and 4-hydroxymethyl pyridines and related electron-deficient heterocycles, permitting novel late-stage drug functionalizations. Preliminary mechanistic studies support a hydrogen autotransfer-type chain process starting with an initial oxidation of the alcohol to the corresponding aldehyde, followed by a subsequent condensation onto indole and reduction/ hydride delivery from another equivalent of the primary alcohol.
Boosting membrane interactions and antimicrobial effects of photocatalytic titanium dioxide nanoparticles by peptide coating.
Authors: Caselli Lucrezia , Parra-Ortiz Elisa , Micciulla Samantha , Skoda Maximilian , Malekkhaiat Häffner Sara , Nielsen Emilie Marie , van der Plas Mariena , Malmsten Martin
Published: October 2023

Photocatalytic nanoparticles offer antimicrobial effects under illumination due to the formation of reactive oxygen species (ROS), capable of degrading bacterial membranes. ROS may, however, also degrade human cell membranes and trigger toxicity. Since antimicrobial peptides (AMPs) display excellent selectivity between human cells and bacteria, these may offer opportunities to effectively “target” coated nanoparticles to bacterial membranes for increased selectivity. Investigating this, photocatalytic TiO2 nanoparticles (NPs) were coated with the AMP LL-37, and ROS generation found by C11-BODIPY to be essentially unaffected after AMP coating. Furthermore, peptide-coated TiO2 NPs retained their positive -potential also after 1-2 h of UV illumination, showing peptide degradation to be sufficiently limited to allow peptide-mediated targeting. In line with this, quartz crystal microbalance measurements showed peptide coating to promote membrane binding of TiO2 NPs, particularly so for bacteria-like anionic and cholesterol-void membranes. As a result, membrane degradation during illumination was strongly promoted for such membranes, but not so for mammalian-like membranes. The mechanisms of these effects were elucidated by neutron reflectometry. Analogously, LL-37 coating promoted membrane rupture by TiO2 NPs for Gram-negative and Gram-positive bacteria, but not for human monocytes. These findings demonstrate that AMP coating may selectively boost the antimicrobial effects of photocatalytic nanoparticles.
Az ügyfél és a hatósági döntéshozatal a digitalizáció korában
Authors: Csatlós Erzsébet
Published: October 2023

The study examines the digital transformation of Hungarian administrative procedure and the advance of automation. Based on statistical data, the study highlights that in connection with digital public administration procedures, the importance of customer-focused services appears as the standard of digital public administration. Digitalization is dominated by electronic contact options, online information and submission of electronic requests, rather than complete automation of administrative procedures. The study focuses on digital authority procedures from the point of view of how this manifests itself primarily for the client: how to satisfy the need for information, how to contact the authorities and how to initiate the procedure. In addition to the legal bases, this part primarily focuses on the possibilities. After that, the consequences of digital solutions (automation) for making substantive decisions from the customer's point of view are discussed; this part of the study therefore concentrates more on the normative side of the processes and finally analyzes this. As a result, it states that automatic decision-making is mainly used in case of registrative acts based on official records and decisions embodied in decision-type documents, but there are already examples of the automation of the decision-making mechanism in connection with the production of facts. Although more complex automation is just spreading its wings, in connection with the rapid technical development and innovations of recent years, the legal system must keep up with digitalization and not give in to it.
Simulation of hydroelastic vibrations of structure elements using finite and boundary element methods
Authors: Vierushkin Ivan , Kononenko Yehor
Published: October 2023

For studying the vibration frequencies and modes of structural elements that operate in interaction with a liquid, an approach has been proposed. The approach is based on coupled usage of finite and boundary element methods. For description the motion of both structural elements and the fluid, the method deals with basic relations of the continuous medium mechanics. In the study of structural elements, the linear relations between stresses and strains have been accepted, i.e. elastic elements have been considered. The relations between the components of stress tensors and strain rates are used to describe the fluid motion. The fluid is considered to be ideal and incompressible. The Laplace equations have been obtained considering the fluid pressure on the wetted surfaces of structural elements. The corresponding boundary conditions have been formulated for one-sided and two-sided contact of a structural element with a liquid. Integral equations for pressure determination have been received. In the case of a two-sided contact of a structural element with a liquid, a hypersingular integral equation has been obtained. If the contact with the liquid is one-sided, then the indicated singular integral equations have logarithmic singularities and Cauchy-type singularities. In the presence of axial symmetry of the structure, these hypersingular integral equations are being reduced to one-dimensional ones. A round elastic plate under different fastening conditions has been considered. Modes of free oscillations of this structural element have been received; these ones serve as basic functions in the study of plate oscillations taking into account the added liquid masses. The finite element method was used. A one-dimensional hypersingular integral equation is implemented to find the fluid pressure on the plate. The frequencies and oscillation forms of the plate have been obtained with considering the attached masses of the liquid. Accuracy and reliability of the proposed method have been ascertained.
Development of workflows based on ontologies
Authors: Globа Larisa , Gaievyi Vadym , Bakai Andrii
Published: October 2023

Modern society is impossible without the digital economy, which increasingly provides a significant amount of services, guaranteeing technological efficiency and innovation, constantly updating technologies and services, adapting them to the needs of the end user, reconfiguring complex software systems. All of this requires constant workflows reengineering in subject areas, and, accordingly, an increase in the level of their automation. At the same time, there are currently no efficient solutions for automated workflows reengineering. This article presents an approach to the computational workflows construction, which is based on well-defined ontological models of the domain, an ontological model of a set of rules for building connections between functional services, and an ontological model of the workflows themselves that are dynamically generated. The research of this approach has been carried out and the prototype for the automated computational workflows construction has been developed. The usage of the proposed approach will increase the level of automation of the computational workflows’ construction, generate workflows "on the fly" based on a previously prepared pool of functional services and restrictions imposed by the ontology domain.
SEI E STEAM: NOVA PROPOSTA PARA ENSINO DA DENGUE E SEU VETOR.
Authors: Nélio Thamiris Silva , Hardoim Edna Lopes
Published: October 2023

Atualmente percebe-se uma inquietação na educação básica acerca da implantação de inovações metodológicas, sobretudo para o alunado da geração “nativo digital”, que requer propostas pedagógicas mais atrativas e interativas.  Tais propostas devem ser orientadas pelas competências e habilidades da Base Nacional Comum Curricular, bem como pelas Diretrizes Estaduais de Mato Grosso, com o intuito de evidenciar uma temática real e relevante para nossos estudantes, conforme a apresentada pela SEI – Sequência de Ensino Investigativo sobre a Dengue e seu vetor. Um produto educacional avaliado por professores de Biologia como inovador e atrativo, cuja metodologia é baseada em métodos de aprendizagem ativa e investigativa (MAAI), aplicável por meio das TDIC – Tecnologias Digitais de Informação e Comunicação. Com vistas à evolução deste produto, propõe-se a incorporação da abordagem STEAM, (Ciências, Tecnologia, Engenharia, Artes e Matemática), que traz como destaque o protagonismo estudantil, melhorando o sentido para a aprendizagem no Ensino Médio. Como resultado, temos a referida SEI incrementada pela abordagem na qual se observa significativa correspondência com os documentos legais, pesquisas e aplicação de propostas em sala de aula que mostraram o desenvolvimento dos pensamentos científico e crítico, tomada de decisão estratégica, bem como a curiosidade, que leva à aprendizagem por investigação.  Assim, almejamos disseminar tal proposta como suporte didático acessível aos professores, com possível aplicação aos estudantes, visto que seria uma oportunidade de se ter aulas mais atrativas, interativas, significativas e integrativas, visando, o conhecimento e a possibilidade de luta contra a Dengue, doença emergente no Estado de Mato Grosso.
Pengembangan Multimedia Interaktif Berbasis Aplikasi Android Untuk Orangtua Dalam Intervensi Keterampilan Berbahasa Siswa Tunarungu
Authors: Indriyati Aminah , Sujarwanto Sujarwanto
Published: October 2023

Hambatan kemampuan berbahasa siswa tunarungu berpengaruh terhadap banyak aspek kehidupannya. Pengaruh hambatan tersebut bisa diminimalkan dengan memberikan intervensi keterampilan berbahasa sedini mungkin, dalam hal ini peran orangtua yang paling utama.Namun kenyataannya sebagian besar orangtua belum melakukan intervensi keterampilan berbahasa saat berada di rumah.Terkait kondisi tersebut penelitian ini bertujuan untuk mengembangkan multimedia interaktif berbasis aplikasi android bagi orangtua untuk intervensi keterampilan berbahasa siswa tunarungu. Penelitian ini menggunakan model pengembangan 4-D Thiagarajan meliputi define, design, develop dan disseminatedilaksanakan sampai tahap develop(pengembangan produk). Teknik pengumpulan datanya meliputi data proses pengembangan dengan teknik validasi ahli media dan ahli materi tunarungu. Kualitasdan kelayakanproduk ditentukan dari hasil analisis skor validasi ahli.Hasil dari validator media sebesar 4,2 dan validator materi sebesar 3,85. Setelah  dikonversikan dengan skor kategori kelayakan maka multimedia interaktif berbasis aplikasi android untuk orangtua dalam intervensi keterampilan berbahasa siswa tunarungu termasuk kategori “sangat layak” untuk media dan “layak” untuk materi. Sehingga media ini dapat digunakan orang tua untuk pendampingan intervensi pengembangan keterampilan berbahasa anak tunarungu secara kontinyu agar anak tunarungu dapat menggunakan bahasa lebih efektif di lingkungan rumahnya.
 
Kata Kunci: intervensi, keterampilan berbahasa, multimedia interaktif, orangtua tunarungu.
Pelaksanaan Pembelajaran Online Bagi Peserta Didik Tunagrahita Ringan Saat Pandemi Covid-19 di Sekolah Inklusif
Authors: Alfiatul Ilmi Dita , Budiyanto Budiyanto , Mudjito Mudjito
Published: October 2023

Penelitian ini bertujuan (1) Menganalisis strategi pembelajaran online; (2) Menemukan kendala pembelajaran online; dan (3) Menemukan faktor dukungan dalam pelaksanaan pembelajaran online  di masa pandemi covid-19 bagi siswa tunagrahita ringan di SMP N 6 Tuban. Penelitian kualitatif deskriptif dengan menggunakan pendekatan studi kasus (case study). Teknik pengumpulan data yang digunakan yaitu diantaranya meliputi: wawancara, observasi dan rekaman arsip. Proses yang di amati meliputi aktivitas peserta didik tunagrahita ringan melalui pembelajaran online mata pelajaran IPS, Agama, PPKN  dengan subjek guru kelas, dan orang tua di sekolah inklusif SMP Negeri 6 Tuban. Hasil temuan strategi pembelajaran online untuk anak tunagrahita ringan di sekolah inklusif  SMP Negeri 6 Tuban guru menggunakan aplikasi online berupa whatsapp dan google classroom sebagai penugasan peserta didik, kendala pembelajaran online materi yang dibagikan tidak sesuai dengan karakteristik peserta didik dengan kebutuhan khusus, semua dukungan pembelajaran menggunakan teknologi.
 Kata Kunci: Tunagrahita, Pembelajaran Online, Pendidikan Inklusif
Kesulitan Analitik Keterampilan Menulis Peserta Didik Sekolah Dasar
Authors: Hidayatun Nuriya , Nahdi Khirjan , Hamdi Zulfadli , Husni Muhammad
Published: October 2023

Tujuan penelitian ini adalah untuk mengetahui tingkat kesulitan analisis keterampilan menulis peserta didik sekolah dasar kelas V MI NW Leneng 2021/2022. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan desain deskriptif. Sampel dalam penelitian ini adalah siswa kelas V sebanyak 20 siswa. Variabel atau variabel tunggal yang digunakan dalam penelitian ini adalah kesulitan analisis keterampilan menulis. Metode pengumpulan data yang digunakan adalah tes dalam bentuk perintah untuk mengetahui capaian kesulitan kemampuan menulis siswa menggunakan serial iamging. Hasil tes pada pertemuan pertama mencapai rata-rata 50,5 berada pada kategori kurang kemudian meningkat pada pertemuan kedua mencapai rata-rata 58 berada pada kategori kurang, selanjutnya pada hari ketiga perolehan rata-rata menurun menjadi 52,5 dengan kategori kurang, selanjutnya pada hari terakhir mencapai rata-rata 60,5 dengan kategori cukup. Hal ini berarti bahwa terdapat kesulitan analitik keterampilan menulis siswa kelas V MI NW Leneng 2021/2022.
Kata Kunci: Kesulitan Analitik, Keterampilan Menulis.
Estimating Hydrodynamic Coefficients of Real Ships Using AIS Data and Support Vector Regression
Authors: Vu Hoang Thien , Park Jongyeol , Yoon Hyeon Kyu
Published: October 2023

In response to the complexity and time demands of conventional methods for estimating the hydrodynamic coefficients, this study aims to revolutionize ship maneuvering analysis by utilizing automatic identification system (AIS) data and the Support Vector Regression (SVR) algorithm. The AIS data were collected and processed to remove outliers and impute missing values. The rate of turn (ROT), speed over ground (SOG), course over ground (COG) and heading (HDG) in AIS data were used to calculate the rudder angle and ship velocity components, which were then used as training data for a regression model. The accuracy and efficiency of the algorithm were validated by comparing SVR-based estimated hydrodynamic coefficients and the original hydrodynamic coefficients of the Mariner class vessel. The validated SVR algorithm was then applied to estimate the hydrodynamic coefficients for real ships using AIS data. The turning circle test wassimulated from calculated hydrodynamic coefficients and compared with the AIS data. The research results demonstrate the effectiveness of the SVR model in accurately estimating the hydrodynamic coefficients from the AIS data. In conclusion, this study proposes the viability of employing SVR model and AIS data for accurately estimating the hydrodynamic coefficients. It offers a practical approach to ship maneuvering prediction and control in the maritime industry.
Macroeconomic Variables and Non-Performing Loans of Banks in Nigeria
Authors: Aliyu A. A.
Published: October 2023

The banking sector holds immense importance in any economy. However, the non-performing loans of Nigerian banks are a concern for the economy and financial stability. This can be attributed to the effects of macro-economic factors on banking activities in the country. The study aimed to examine macroeconomic variables and the non-performing loans of banks in Nigeria. A descriptive research design method was used for the study. Secondary data were collected for the period from 1990 to 2021. The auto regressive distributed lag (ARDL) error correction model was used for data analysis. The study’s results show that tax revenue, recurrent expenditures and the real interest rate will in the long run resolve the problems of non-performing loans of banks in Nigeria. Contrarily, money supply and exchange rate, if not properly managed, may amplify non-performing loans of banks in Nigeria. The study concluded that macroeconomic variables, when properly devised, will help subdue the problem of increasing non-performing loans in Nigeria.
Does Price Discrimination Increase Social Welfare?
Authors: Poudel S. , Nepal D.
Published: October 2023

The process of charging a different price to a different group of consumers for similar goods and services is called price discrimination. The relationship between price discrimination and social welfare has been an important topic of research and discussion for many years. The purpose of the study is to determine the conditions under which price discrimination improves or reduces social welfare. The authors used a method of series of literature reviews to gather information about the relationship between price discrimination and social welfare. The study showed that price discrimination can improve social welfare if output is increased. The increase in output increases social benefits and overcomes the loss of welfare due to the inefficient distribution of products. The key conclusion is that the social benefits of price discrimination are the availability of essential services to low-income groups and the maintenance of equity in the consumption of public goods. This study has major implications for the formulation of a policy that introduces price discrimination to maintain equity among different income groups and ensure the availability of high-cost essential services.
Economic Factors Influencing Housing Prices in Pakistan
Authors: Khan M. T.
Published: October 2023

The aim of this research is to explore the factors influencing housing prices in Pakistan. The author used monthly time series data for the period from 2011 to 2020, which were obtained from different sources: housing prices data from zameen.com, Karachi interbank offered rate (KIBOR) as a proxy for monetary policy, consumer price index as a proxy for inflation, and exchange rate data from the State Bank of Pakistan. Various methods, such as autoregressive distributed lag (ARDL), comparative analysis and deductive analysis were employed. Before using the ARDL technique, a proper lag length was selected, which turned out to be 11 months. Various diagnostic tests indicated model stability with no autocorrelation or structural breaks. The author concluded that the KIBOR rate negatively affected housing prices, while inflation and exchange rates affected house prices positively.
A Socio-Legal Study on Vaccine Tourism in the Context of Covid-19 Travel Restrictions
Authors: Farooqui Mohammad Owais , Alshdaifat Shadi A. , Siddiquei Mohd Imran
Published: October 2023

The COVID-19 pandemic has affected the tourism industry harshly. The most effective way to steer clear of the virus is global vaccination. A novel concept of vaccine tourism arises from vaccine manufacturing corporations' limited stock and production capacity. The current paper aims to demystify the socio-legal and ethical underpinnings of vaccine tourism as well as analyze the restrictions on international travel imposed by major countries. The research critically examines key issues considering the literature's current arguments and integrates the current developments and challenges in the field of vaccine tourism. The paper addresses the fact that, in the current circumstances of travel restrictions, insufficiency of raw materials, ambiguous policies, vaccine passport authenticity, skewed distribution, and scarcity of vaccines around the world, the implementation of vaccine tourism is a big challenge. The study tries to understand the emerging concept of vaccine tourism and the major challenges to its growth. Vaccine tourism may be an instrument to revive the tourism sector post-COVID; therefore, understanding the current emerging issues around it would be significant for tourism literature. Doi: 10.28991/ESJ-2023-07-05-012 Full Text: PDF
Ocular Microbiota of Severe Meibomian Gland Dysfunction (Chronic Dry Eyes) after Intense Pulsed Light (IPL)
Authors: Wongsaroj Lampet , Pongpirul Krit , Watthanathirakawi Attawut , Wanumkarng Nattawut , Iam-a-non Anchana , Dean Deborah , Somboonna Naraporn
Published: October 2023

Ocular IPL therapy has recently been widely used for MGD, especially for patients not showing improvement with traditional therapies (warm compresses and lid scrubs) to clean debris and reduce bacterial overgrowth. Insights on the ocular microbiome and quantitative microbiome in MGD after a course of IPL could provide useful data on bacterial community monitoring and associated mechanisms linked with IPL. Ocular swabs were obtained from a severe MGD patient and age-sex matched healthy for metagenomics, followed by 16S rRNA gene sequencing and qPCR. Of 10 samples, including left and right eyes (el, er) of severe MGD females before (Db) and after 2-4 IPLs (Da2, Da3, and Da4) and the matched non-MGD females (H), both of ~40 years Using 16S rRNA gene sequencing as microbiota and combined 16S rRNA gene qPCR as quantitative microbiota revealed significant disperse in the microbiome structures of Db compared with Da and H (HOMOVA, p<0.001). Bacterial Propionibacterium acnes and unclassified taxa in the family Propionibacteriaceae and order Actinomycetales represented the core Db microbiota and were reduced after 2-4 IPLs in Da, making the Da microbiome and clinical (mucocutaneous junction, corneal, and conjunctival fluorescein score) closer to H (NMDS with Pearson’s correlation, p<0.05). The recovery of the Da microbiome also allowed Da metabolic potentials to be closer to H. Our findings first demonstrated the ocular microbiome dysbiosis in severe MGD, dispersed from Da and H, in Thai subjects, correlated with bacterial quantity and clinical MGD, including the mucocutaneous junction process. The results additionally provided taxa representing Db vs. Da and H and preliminarily underlie the idea that IPL could improve dysbiosis in the MGD microbiome. Doi: 10.28991/ESJ-2023-07-05-015 Full Text: PDF
The Impact of Drug Abuse and Delinquency on Educational Environment Security
Authors: Orlova Vera V. , Shevchenko Larisa V.
Published: October 2023

Creating and maintaining a secure and supportive educational environment is essential for the success and well-being of university students. This study investigates the interplay between drug abuse, delinquency, sociocultural factors, and the security of the educational environment. Drawing upon a sample of 356 students from the Federal State-Funded Institution of Higher Education—Tomsk State University of Control Systems and Radioelectronics (TUSUR), we employed a partial least squares structural equation modeling (PLS-SEM) approach to analyze the data. The findings indicate that sociocultural security significantly influences students' behavioral intentions, with a confirmed negative impact on the intention to commit delinquency (β = -0.461, p < 0.05). Additionally, student well-being demonstrates a significant negative relationship with the intention to use drugs (β = -0.583, p < 0.01) and the intention to commit delinquency (β = -0.714, p < 0.001). However, the impact of sociocultural security and well-being on the intention to use drugs was not confirmed (β = -0.731, p > 0.05). Furthermore, the study reveals that students' behavioral intentions significantly affect the security of the educational environment. The intention to use drugs and the intention to commit delinquency negatively impact the security of the educational environment (β = -0.635, p > 0.05; β = -0.660, p < 0.05, respectively). These findings contribute to the understanding of the complex dynamics that shape the educational environment in universities. The study highlights the importance of promoting sociocultural security and fostering student well-being to prevent negative behavioral intentions and maintain a secure learning environment. Doi: 10.28991/ESJ-2023-07-05-018 Full Text: PDF
“Bone marrow edema” in the differential diagnosis of traumatic injuries of the knee
Authors: Torgashin A. N. , Rodionova S. S. , Morozov A. K. , Torgashina A. V. , Magomedgadzhiev R. M. , Fedotov I. A.
Published: October 2023

Bone marrow edema is MR images is defined by the presence of hypointense infiltration on T1-weighted images and clear high signal intensity on fat-saturated T2-weighted sequences (T2 FSE FAT SATURATED, T2-weighted short-tau inversion recovery (T2w-STIR)).

Aim: To demonstrate the features of manifestation of “bone marrow edema” at different severity and character of traumatic injury of the knee.

Materials and Methods. A series of clinical cases with subchondral bone involvement in the form of “bone marrow edema” resulting from trauma is presented using the example of the knee joint as the most common area of MRI for differential diagnosis.

Results. The features of “marrow edema” of the femoral and tibial condyles were analyzed using clinical examples. It was shown that the severity and nature of injury can be judged by the nature of the edema, presence of linear hypointensities, articular surface deforms and the bone defects.

Conclusion. Evaluation of “bone marrow edema” revealed on MRI examination in case of pain syndrome after a knee joint injury allows timely clarification of the diagnosis and adequate treatment.
Possibilities of densitometry in the assessment of diffuse changes in the lung parenchyma
Authors: Suchilova M. M. , Blokhin I. A. , Kodenko M. R. , Reshetnikov R. V. , Nikolaev A. E. , Omelyanskaya O. V. , Vladzymyrskyy A. V.
Published: October 2023

The data obtained from chest computed tomography (CT) can be analyzed not only visually, but also quantitatively. Quantitative assessment allows a more accurate and objective evaluation of the disease severity. Densitometry is the most researched way to quantify CT data – automatic analysis of lung densities expressed in Hounsfield units. This review is focused on the types of diseases that can be characterized by the formalization of the diagnostic task and application of densitometry, as well as on the limitations of the method and the ways to cope with them.
Assessment of the effectiveness of measures to improve the patient routing system in the provision of planned medical care (experience of Tomsk region)
Authors: Babeshina M. A. , Baranovskaya S. V. , Boykov V. A. , Deev I. A. , Kobyakova O. S. , Perfilieva D. Y. , Protasova L. M. , Sirotina A. S. , Taranov A. A. , Shibalkov I. P.
Published: October 2023

Introduction. This article reviews the results of the development and implementation of organizational solutions aimed at reducing the time of providing routine medical care to patients in outpatient settings and increasing its availability. Among the reasons negatively affecting the waiting times for medical care are complex routing schemes and the high level of administrative overhead that accompanies each stage of the treatment and diagnostic process.

Aim: To develop and evaluate the effectiveness of measures to improve the system of organization of planned medical care on the example of medical organizations of Tomsk region.

Material and Methods. The study included medical organizations providing primary health care in outpatient settings (31 institutions). The study was conducted in stages: 2018–2019 the main set of measures (creation of offices of the organization of planned care) was developed and implemented, 2020–2021 – summarized interim results, 2022 – performance assessment was carried out. For comparative analysis all medical organizations were divided into 2 groups (group A and group B) depending on implementation of planned activities. Statistical processing was performed using the Statistica 10.0.228.8 software package.

Results. It was found that the waiting time for a doctor’s consultation Group A reduced by 5.5% (p = 0.025) in 2019 compared with 2018, in contrast to Group B. The waiting time for a routine diagnostic examination in Group A also reduced by 16.6% in 2019 compared to 2018 (p = 0.041), while no differences were found between waiting times for routine diagnosis in Group B for the same period (p = 0.101).

Summary. The study has shown that the problems of accessibility of planned medical care can be effectively solved through the creation of a patient flow management system at all stages of the treatment and diagnostic process.
Clinical aspects of virtual reality technologies application in cognitive rehabilitation of patients with cardiovascular diseases
Authors: Tarasova I. V. , Trubnikova O. A. , Kukhareva I. N.
Published: October 2023

This analytical review considers the clinical aspects of the application of virtual reality (VR) technologies in the cognitive rehabilitation of patients with cardiovascular diseases. It is shown that VR-training is one of the actively developing rehabilitation methods. Its use has great potential for the treatment of cognitive disorders of a wide range (stroke, vascular cognitive disorders, cardiac surgery patients). Promising in the development of personalized approach in the cognitive rehabilitation of cardiac patients is the estimation of the initial level of cognitive reserve as an indicator of the possible activation of neuroplastic processes against the background of cognitive training using a virtual environment.
Native T1- and T2-mapping of myocardial relaxation times in cardiovascular magnetic resonance: clinical applications
Authors: Mershina E. A. , Ryzhkova E. V. , Lisitskaya M. V. , Kharlap M. S. , Sinitsyn V. E.
Published: October 2023

Cardiovascular magnetic resonance is widely used due to its possibilities for noninvasive cardiac tissue characterization. In recent years native myocardial T1- and T2-mapping techniques have been implemented in routine practice. These techniques provide quantitative analysis of myocardium and allow detection and evaluation of myocardial damage without the need for gadolinium-based contrast agents. In this review we would like to discuss application of native T1- and T2-mapping in different types of heart disease.
ARCH-COMP23 Repeatability Evaluation Report
Authors: Johnson Taylor T
Published: October 2023

The repeatability evaluation for the 7th International Competition on Verifying Continuous and Hybrid Systems (ARCH-COMP’23) is summarized in this report. The competition took place as part of the workshop Applied Verification for Continuous and Hybrid Systems (ARCH) in 2023, affiliated with the 2023 Cyber-Physical Systems and Internet- of-Things Week (CPS-IoT Week). In its seventh edition, tools submitted artifacts through a new automated evaluation system and were synchronized with a Git repository for the repeatability evaluation and archiving, which were applied to solve benchmark instances through different competition categories. Due to procedural changes in execution through the automated system, fewer participants than in past iterations participated in the repeatability evaluation this year. The process was generally to submit scripts to automatically install and execute the tools in containerized virtual environments (specifically Dockerfiles to execute within Docker containers, along with execution scripts). With the automated evaluation system, most participating categories presented performance evaluation information from this common execution platform.
Influence of Adding Demolition Wastes on the Mechanical Properties of Concrete in Sultanate of Oman
Authors: Almaawali Said , Alhamrashdi Samiya , Alsiyabi Ameera
Published: October 2023

Nowadays the global trend in construction industry is to reduce the cost, saving energy and preserving the environment. Using other industries' waste material as a construction material is one of several methods followed to meet these trends. Management of solid waste is considered as one of the most significant environmental issues not only in a country like Oman, but globally as well. Around 1.7 million tons of solid waste is yearly generated in Oman. More than 120 million tons of constriction demolition waste is yearly generated over the world. Besides, 10-30 % of solid wastes produced from construction field (concrete wastes and aggregate) in Oman is just dumped in the landfill area without any further use. In this paper, the influence of replacing the demolition waste with coarse aggregate on the mechanical properties of concrete was studied in terms of compressive, flexural, and tensile strengths, and workability. The concrete properties were evaluated by replacing of 20, 30 and 40% of coarse aggregates with demolition waste in the mix proportion of C-35 concrete and the experiment's results were compared with each other as well as with the conventional one, based on two different periods of 7 and 28 days. The results were satisfactory so it could be concluded that replacing of up to 40% of coarse aggregates with construction and demolition waste is still safe and not causing dramatic reduction in the concrete strength.
Moral Education in Wasiat Renungan Masa by TGKH. Muhammad Zainuddin Abdul Madjid: An Examination of Ibn Miskawaih's Philosophy
Authors: Atsani Lalu Gede Muhammad Zainuddin , Nasri Ulyan , Walad Muzakkir , Yakin Hakkul , Zulkifli Muh.
Published: October 2023

This research discusses the moral education found in “Wasiat Renungan Masa” by TGKH. Muhammad Zainuddin Abdul Madjid through an examination of Ibn Miskawaih's moral philosophy. The aim of this study is focused on understanding moral education within “Wasiat Renungan Masa” by using the lens of Ibn Miskawaih's moral philosophy. The research method employed is a literature analysis, which includes the identification of research objectives, data identification, data collection, data selection, data extraction, thematic analysis, comparison, contrast, pattern identification, as well as research conclusions and implications. The results of this study indicate that moral education in "Wasiat Renungan Masa" by TGKH. Muhammad Zainuddin Abdul Madjid, as examined through the philosophy of Ibn Miskawaih, emphasizes the importance of self-development and morality in living life. Through concepts of self-discipline, moral exercises, and the cultivation of good character, humans have the potential to attain spiritual happiness and moral perfection. The conclusion of this research provides a deeper insight into the moral values within these works and their relevance in the context of contemporary moral education. This research has practical implications in the development of moral education, the formation of individual character, and the enrichment of moral thought in an increasingly complex and changing society.
Definition of graphic signatures for solid surface vibrations
Authors: Aleixo Leonardo Guimarães
Published: October 2023

Esta pesquisa reúne estudo de modelos matemáticos
para a predição de padrões numéricos e assinatura gráfica sobre
a resposta de impulso de vibrações. A coleta de dados reunida
recebe a análise de processamento computacional, com a aplicação
de funções que definem a linearidade de conjunto de valores e
obtém a resposta de polinômios para a amplitude de sinal. A
Meta-heurística define comportamento não determinístico através
de otimização Busca-tabu, resposta de dispersão por limites de
dados e por fim definindo a estabilidade de impulso das amostras.
Matemática e Astronomia: Relatos da Participação dos Alunos de Uma Escola Pública no Universo da Pesquisa Cientifica.
Authors: Fortes Janielli de Vargas
Published: October 2023

Este artigo apresenta um relato de experiência, realizado em uma Escola de Ensino
Fundamental do município de Linhares ES, com alguns alunos de 9o Ano. A reflexão teórica
deve-se a participação da Escola EMEF Prefeito “Roberto Calmon” na Mostra deAstronomia
do Estado do Espírito Santo, participação esta que rendeu dois trabalhos premiados: um em
2020 (Terceiro lugar categoria 9o Ano) e um em 2021 (Primeiro lugarcategoria 9o Ano). Vale
ressaltar que a premiação é bem-vinda, entretanto a participaçãodos alunos em grupos de
iniciação cientifica do CNPq, foi de fato o mais importante. Este trabalho teve como principal
objetivo, oferecer aos professores um material de consulta com boas informações, descrever as
etapas percorridas durante a pesquisa e apresentação dos projetos, bem como os pressupostos
teóricos envolvidos. Como principais resultados, temos a divulgação científica de astronomia e
matemática aplicadapara medir grandes distâncias no espaço, e o manuseio dados científicos.
Também, esperamos que esse relato seja de incentivo para professores pesquisadores que
também estão atuando na educação básica, para que aproveitem materiais como esse para as
aulasde matemática.
Literature review: The effect of environmental arrangement on malaria incidence in dry tropical climate areas in NTT
Authors: Cornelia Hildegardis  , Maria Carolin Tandafatu  , Agustina Alfonsa Jae
Published: October 2023

"Indonesia Bebas Malaria 2030" is the Indonesian government's target proclaimed by the Indonesian Ministry of Health at this time. This set target is inversely proportional to several discoveries found in eastern Indonesia, especially East Nusa Tenggara. For example, in 2022 in Sikka Regency, there will be an increase in malaria cases reaching 55 people. Based on research conducted in Africa, it is known that the treatment of malaria can not only be overcome by medication but by improving the physical environment such as housing and the surrounding environment. Therefore, an article search was carried out in several reputable journals for the past ten years to determine the influence of external and internal environmental settings on the incidence of malaria, especially in the East Nusa Tenggara region. From the search that has been done, it is known that environmental factors provide and biological factors are the factors that most influence the thermal characteristics of the incidence of malaria in NTT.
International Café: A Collaborative approach to international student wellbeing and support
Authors:   Murdoch University, Devezy Yohann , Hill Braden ,   Edith Cowan University, Beresford Liz ,   Edith Cowan University, Williams Rose ,   Murdoch University, Farr Shirley ,   Murdoch University, Readman Em ,   Murdoch University, Mermejo Clair ,   Edith Cowan University
Published: October 2023

Prior to 2020, ongoing discourse in the higher education sector underscored the increasingly complex mental health and wellbeing challenges faced by students. The “post-COVID-19” period witnessed a resurgence of international students arriving in Western Australia. Emerging cost of living pressures, accommodation shortages, and changing visa work hours have amplified the distinct challenges international students encounter, prompting renewed discussions surrounding a need for effective support interventions. Drawing inspiration from successful initiatives at Edith Cowan University, Murdoch University introduced the Murdoch International Café—a program focused on providing distinct spaces of support for international students. This supportive environment enables social connection, effective information sharing, and normalised student challenges and support seeking behaviour. Additionally, Murdoch University's Virtual International Student Hub (VISH) extends this support online. In this paper, collaborative autoethnographic methods offer insights into the efficacy of these initiatives and further explore how these proactive, student-centric mental health interventions potentially cater to the evolving needs of international students.
Protección de los principios del Estado de Derecho en la Unión Europea mediante la condicionalidad financiera
Authors: López Escudero Manuel
Published: October 2023

El Estado de derecho es uno de los valores fundamentales de la Unión Europea. La proliferación de gobiernos “iliberales” ha multiplicado las violaciones de este valor y se han puesto de manifiesto las limitaciones del derecho de la UE para protegerlo. Por ello, se ha creado un procedimiento adicional para salvaguardar el valor Estado de Derecho, que utiliza el mecanismo de la condicionalidad financiera, mediante el Reglamento 2020/2092. Polonia y Hungría han atacado dicho Reglamento con sendos recursos de anulación y el TJUE ha confirmado su compatibilidad con el derecho originario, despejando el camino para su aplicación por la Comisión y el Consejo.