bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis territorialista de la morfología urbana para un desarrollo policéntrico y equilibrado del territorio del bajo Guadalquivir
Authors: Merino-Del-Río Rebeca , Linares-Gómez-del-Pulgar Mercedes , Tejedor-Cabrera Antonio
Published: September 2024

Con el fin de avanzar en un desarrollo más equilibrado de los territorios se establece un método para extraer el carácter policéntrico y reticular de los sistemas de los asentamientos basado en un análisis de la morfología urbana. El método se fundamenta en la aproximación de la escuela territorialista italiana al diseño y el planeamiento urbano y territorial. Se utilizan como referencias prácticas los planes paisajísticos territorialistas de la Toscana y la Puglia. Para demostrar el funcionamiento del método, este se aplica al territorio del bajo Guadalquivir, donde impera un tipo de urbanización compacta. Se presentan algunos posibles beneficios de la aplicación del análisis al planeamiento territorial sevillano, como la redefinición de los ámbitos de paisaje o el diseño de un sistema de infraestructuras para la movilidad lenta, y se evalúan las fortalezas y debilidades del método.
Impacto social del urbanismo de las ciudades emprendedoras: el caso del 22@ Barcelona y sus afectaciones en la vida cotidiana del vecindario
Authors: Martín-Gómez Albert , Sales-Favà Joan
Published: September 2024

El 22@ de Barcelona se presenta como un proyecto insignia de ciudad global por haber desarrollado la regeneración urbana y económica de un antiguo barrio industrial. Mientras tanto ha permanecido en paralelo una crítica latente del asociacionismo vecinal sobre la cobertura de necesidades sociales del vecindario. Este artículo evalúa mediante un método mixto la percepción ciudadana sobre el impacto social tras 20 años de desarrollo del plan 22@. Los principales resultados sobre el empleo, el comercio, la vivienda y el patrimonio muestran una relación significativa diferenciada en función de: la edad, si son residentes en el barrio o trabajadores; y el tiempo que hace que son vecinos. En términos generales el análisis de la percepción ciudadana muestra como la implementación del plan 22@ hubiera relegado la cobertura de necesidades sociales locales a las económicas globales.
¿Cómo de complejo es el tejido urbano de la ciudad de Madrid?: un análisis de la mezcla de usos a nivel de parcela catastral
Authors: García-Álvarez David
Published: September 2024

La complejidad urbana hace referencia a la mezcla de funciones o usos en la ciudad. Está relacionada con un modelo de ciudad de proximidad o la denominada “ciudad de los 15 minutos”. Este modelo de ciudad está recibiendo creciente atención mediática y ciudadana, por lo que resulta propicio diagnosticar cuál es la situación actual en la ciudad de Madrid. En este estudio, se utilizan los datos catastrales para identificar aquellas zonas de Madrid donde existe un tejido urbano complejo, con mezcla entre usos residenciales y otras funciones, y aquellas zonas en las que predomina un único uso. El análisis se realiza a nivel de parcela catastral, si bien se proporcionan datos de diagnóstico a escala de distrito y sector urbano. Los resultados revelan una clara asociación entre los tejidos urbanos complejos y la ciudad histórica, así como una especialización residencial del norte de Madrid.
Incidencia de la actividad turística en la configuración urbana de las ciudades históricas: caso de estudio Granada (España)
Authors: Ruiz-Zafra Gabriel , Lamas-Fernández Francisco
Published: September 2024

Granada, como ciudad histórica, se ve afectada por la alta demanda del mercado turístico, catalizador de la transformación del modelo urbano y factor de fenómenos como gentrificación, turistificación y pérdida de características urbanas. Este trabajo analiza la evolución del tejido urbano del centro histórico de Granada con el fin de comprender el desarrollo del espacio público, el cambio del comercio local y la mutación del tejido residencial. Se realiza mediante una aproximación cartográfica. Seguidamente, se evalúa las diferentes normas y planes urbanísticos, para identificar el modelo de planificación urbana actual. Los resultados muestran una desviación entre la realidad y las propuestas existentes de planificación, ofreciendo una ilustración relevante para entender las divergencias entre el mundo técnico y académico de las necesidades reales y los acontecimientos de la sociedad contemporánea.
Psychedelics as novel therapeutic agents for chronic pain: mechanisms and future perspectives
Authors: Yasin Bushra , Mehta Shivani , Tewfik George , Bekker Alex
Published: September 2024

Chronic neuropathic pain is a significant public health issue affecting an estimated 1.5 billion individuals worldwide. The mechanisms underlying chronic pain are multifaceted and not fully understood. Chronic pain amplifies specific neural pathways through peripheral and central sensitization triggered by repeated exposure to noxious stimuli, ultimately resulting in physical and emotional pain. Traditional treatment options targeting these mechanisms, such as opioid and non-opioid analgesics, are associated with adverse effects, addiction, and suboptimal pain relief. Using psychedelics to treat chronic pain is an area of growing interest. While psychedelic substances, such as psilocybin, lysergic acid diethylamide, mescaline, and 3,4-methylenedioxymethamphetamine are primarily associated with recreational use or spiritual practices, emerging evidence suggests their potential therapeutic benefits for various mental health disorders, including chronic pain. Psychedelics alter pain perception by directly activating serotonin receptors, exerting anti-inflammatory effects, enhancing descending inhibition, opening a window of neuroplasticity, and facilitating synaptic remodeling. This review mainly elucidates the ongoing research regarding the psychedelic mechanisms of action, pharmacology, clinical applications, and therapeutic potential in treating neuropathic pain.
nueva época ambientalizada del Derecho de aguas chileno, y las exigencias y medidas de adaptación derivadas de la ley marco de cambio climático
Authors: Rojas Calderón Christian
Published: September 2024

El presente trabajo trata con cierta detención los cambios y avances que se han producido en la tradicional regulación de aguas chilena, en especial a partir del año 2022, profundizando su administrativización y ambientalizando dicha normativa. Y trata asimismo, de los efectos de otra regulación —Ley Marco de Cambio Climático—, y su conexión con la reforma de aguas en sus aspectos ambientales, particularmente acerca de un instrumento de adaptación al cambio climático como son los planes estratégicos de recursos hídricos en cuenca (PERHC); enjuiciándolos críticamente, tanto dichos planes como la reforma en general.
Optimizing Regional Revenue through Sustainable Regional Planning (Case study: Lolai Toraja Tourism Area)
Authors: Suhaeb M Iqbal
Published: September 2024

The Toraja region in South Sulawesi, which is currently divided into Tana Toraja Regency and North Toraja Regency, are two districts in South Sulawesi Province that rely on the tourism sector as the main driver of the regional economy. Various types of tourism destinations have emerged, one of which is the tourism destination in the Lolai Tourism Area. This has various impacts, including social, cultural, economic and environmental aspects of the settlement. This research aims to analyze the influence of the development of tourist attractions in the Lolai area on the surrounding residential environment and examine sustainable tourism development strategies in the Lolai Tourism area. This research uses descriptive analysis methods using qualitative and quantitative analysis. Samples from heads of families used purposive sampling to produce 75 families, and data were collected using questionnaires. The results of the research show that there is a joint economic, social and environmental impact on the development of the country's tourist attraction above the Lolai clouds, there is a partially significant economic, social and environmental impact on the development of the country's tourist attraction above the Lolai clouds, and there is an influence the most significant environmental variable for the development of the Lolai tourist attraction. Based on the results of the strategic analysis of sustainable tourism development strategies in the Lolai tourist area, it is then processed using SWOT analysis, producing directions that lie in the direction of S-O (Strength–Opportunity) or Growth (Development) to increase strength by taking advantage of existing opportunities. The managerial implication in this research is as a strategy recommendation that can be implemented for local governments and managers to develop the Lolai tourist area and increase the interest of domestic and foreign tourists to travel to the Lolai tourist area.
First record of papaya as host of carambola fruit fly in Brazil
Authors: Costa José V. T. A. , Sousa Maria do S. M. de , Souza-Filho Miguel F. de , Lemos Lailson do N. , Pantoja Elizane V. , Nava Dori E. , Adaime Ricardo
Published: September 2024

In this work we report for the first time in Brazil the occurrence of carambola fruit fly Bactrocera carambolae Drew & Hancock, 1994 (Diptera: Tephritidae) in fruits of Carica papaya L., from samples collected in the municipalities of Almeirim, state of Pará, and Mazagão, state of Amapá. These findings are discussed in the context of Brazilian fruit growing.
Scanning electron microscopy and light microscopy of tongue, fingers, toes, nuptial pad, and humeral gland in Sylvirana nigrovittata (Anura: Ranidae)
Authors: Chuaynkern Chantip , Rongchapho Peerasit , Hanjavanit Chutima , Simmasian Wanchai , Phochayavanich Ratchata , Chuaynkern Yodchaiy
Published: September 2024

The micromorphology and histology of anuran skin, particularly in Thai species, remain relatively understudied. Anurans use their tongues for prey capture and their hands and feet for adhesion and mating, suggesting a close relationship between micro-surface features and histological structure. Information on Sylvirana nigrovittata is particularly limited. This study provides a detailed examination of the micro-surface and histological characteristics of the tongue, fingers, toes, nuptial pad, and humeral gland in S. nigrovittata. Specimens collected from Phu Luang Wildlife Sanctuary in Loei province, northeastern Thailand, were studied using scanning electron microscopy (SEM) for micro-surface features and H&E staining for histological details. SEM micrographs revealed that the tongue was cordate-shaped, with about 75% of its surface covered by filiform papillae and 25% by fungiform papillae housing taste buds. Filiform papillae were trapezoidal, averaging 23.88±5.68 µm in width and 38.83±6.57 µm in length, while fungiform papillae were disc-like, averaging 52.95±14.64 µm in width and 66.70±15.88 µm in length. Digital pads on fingers and toes presented prismatic cells, with fingertip cells averaging 7.09±0.97 µm in width and 11.81±1.24 µm in length, and toe cells averaging 8.40±1.37 µm in width and 11.28±1.63 µm in length. Subdigital surfaces were smoother, containing squamous cells with dimensions of 10.65±3.21 µm in width and 21.29±4.35 µm in length. Subarticular tubercles were composed of prismatic cells with hexagonal or pentagonal surfaces, averaging 10.02±2.85 µm in width and 13.08±1.94 µm in length. Nuptial pad displayed cylindrical structures with dome-like tips, averaging 24.01±3.96 µm in width and 21.16±4.37 µm in length, and feature mucous openings. They consisted of a thick keratinized stratified squamous epithelium and a dense dermis with specialized mucous glands. Humeral gland exhibited rough surfaces with squamous cells and microridges, showing both small and large mucous openings, with average cell dimensions of 16.23±1.70 µm in width and 19.11±2.05 µm in length. Histological analysis confirmed that these structures were predominantly composed of keratinized stratified squamous epithelium, with variations in dermal collagen density and mucous gland distribution. This study enhances our understanding of the skin and gland morphology in S. nigrovittata, highlighting on its anatomical and functional adaptations.
Methods for optimizing additive technologies using the example of loaded plastic products
Authors: Prokopenko Nikita M.
Published: September 2024

The article describes the development of methods for optimizing additive technologies (FDM printing), taking into account the loads acting on the body in question, in order to save materials and reduce production time, within the framework of robotics, shipbuilding and the development of water, land and air drones. An analysis of existing modification methods to strengthen models was carried out. Various methods of modifying 3D models for printing have been tested. Based on the tests, a universal method for strengthening parts for three-dimensional printing was proposed and developed. The method is based on the principle of creating spherical cavities inside the part in place of the most loaded areas of the part, which then, when creating G-code programs for the printer, will be surrounded by outer plastic walls, creating a seal inside the part. Inventor and Ansys stress analysis and topology analysis are used to identify areas requiring optimization, based on the results of which 3D models of the most loaded areas, or models of areas requiring reinforcement, were created. A software and hardware complex has been created for modifying three-dimensional models for 3D printing and a software has been developed to automate the main parts of the processing technique for finished parts - creating cavities based on a three-dimensional model of loaded zones.
The effectiveness of the logistics systems of the APEC countries
Authors: Puzevich Vladislav I. , Orlova Lyudmila G. , Pochekaeva Olga V.
Published: September 2024

The Asia-Pacific Economic Cooperation Forum is an international union for collaboration in the field of regional trade, simplification and liberalization of investments, which serves the interaction of countries and their economic sectors with various stages of development. Transport and logistics systems are necessary to offset the shortcomings caused by issues with safety, usefulness and, most importantly, supply efficiency. The forum's management regularly works out strategies to solve these problems without noticeable losses for resource bases such as financial security and labor. Significant differences in the development of the association countries require an analysis of the effectiveness of logistics as a tool for the growth of the participating economies, ensuring conditions for constant progress and adaptation of the best foreign experience. The authors concluded that the degree of infrastructure quality affects the effectiveness of logistics services, confirmed the close relationship between the level of economic competitiveness of the country and the degree of its logistics efficiency, found out that the criteria for logistics efficiency are based on indicators of the pace of digitalization of transport activities. It is also established that Russia is one of the regions that can be characterized as catching up with the rest in terms of logistics efficiency, therefore, domestic transport industry specialists should study and, depending on the conditions, introduce technologies from the world's leading global players, creating a comparative advantage over other participants.
Numerical methods for optimizing logistics systems in the process of inventory management
Authors: Chebotarev Stanislav S. , Khaitbaev Valery A. , Butchenko Viktor V.
Published: September 2024

Scientists have always faced the task of evaluating the effectiveness of the functioning of complex systems, which unambiguously include logistics systems of transport (water, air, rail, automobile and their combinations) and stocks of products (goods), which (stocks of goods) are in static (warehouses) and dynamic (transport) states over time. A huge amount of theoretical material has been accumulated in this field of knowledge, which has been repeatedly tested and successfully applied, especially in relation to logistics systems. However, as is known, on the basis of an efficiency assessment, similar systems are compared, the operation of the systems is promptly evaluated, the system's compliance with its purpose is checked, the presence or absence of targeted targeting is found out, etc.
       Hence, the relevance of the mathematical apparatus (numerical methods) for optimizing stocks of products (goods) is determined as a calculation for reasoned decision-making on effective inventory management using transport and storage capacities on an economic basis: the objective function is to minimize costs. Cost reduction in the processes of functioning of logistics systems due to the action of two basic laws – the law of saving time and the law of conservation of energy is one of the main modern directions for increasing their efficiency as complex systems [1-5].    
       Therefore, the optimization of logistics systems according to the criterion of costs (losses) in the processes of their functioning is defined as the formulation of the research task.
       The aim of the work is to develop the application of numerical methods for optimizing logistics systems in the process of inventory management. The novelty consists in the application of numerical methods and the calculated ratios obtained, which can be used in the practice of the logistics system of water, air, rail and road transport for inventory management by optimizing the determined losses (costs).
       The result consists in the developed method of studying theoretically calculated losses occurring in the processes of functioning of logistics systems of all types of transport and their combinations (hereinafter transport).
    The theoretical significance of the results obtained is the development of the application of numerical methods for optimizing logistics systems in the process of inventory management, including: a set of factors and criteria for optimizing logistics processes; a method for modeling and optimizing the processes of functioning of logistics transport systems; a method for analyzing losses in the processes of functioning of logistics transport systems. These theoretical provisions make it possible to optimize the processes of functioning of logistics transport systems and, ultimately, to increase the efficiency of providing consumers, which is of important socio-economic importance.
Sacrococcygeal Teratoma: Tales of the “Tailbone” Tumour in a Newborn
Authors: Tharveen Nair Chandrasekaran  , Jia Yee Pwi  , Bhuwaneswaran Vijayam
Published: September 2024

Sacrococcygeal teratoma (SCT) is a rare tumour with a low incidence, but it is the most common extragonadal tumour in the newborn. It occurs at the base of the coccyx (tailbone) and is derived from embryonic germ cell layers. Although the majority are benign in nature, they are associated with significant morbidity and mortality for the mother and the foetus. A multidisciplinary approach is needed where an accurate early diagnosis should be made antenatally, leading to anticipation of complications during intrapartum for the mother and foetus, and ultimately early, complete surgical excision of the tumour. The prognosis for survival is good after resection. We report a case of a newborn delivered at 29 weeks who was diagnosed with SCT at post-partum but unfortunately passed away due to the complications of prematurity before surgery could be performed. This case report highlights the literature review of this pathology, especially the management of SCT, which begins in the antenatal period soon after the diagnosis is made.
Prospecting and Identification of Fungi Associated with the Rice Leaf Scald Disease in Togo
Authors: Sadate Amadou , Djodji Kossikouma Adjata , B. P. I Tchaou Bodjona , N’pagyendou Lare , Djobo Ashrafou Ouro , Aminou Saibou , Messan Koussakana Dewa Kassa
Published: September 2024

Leaf scald, caused by Rhynchosporium oryzae, is the third most damaging rice fungal disease worldwide after blast and helminthosporiosis. This study presents the first report of leaf scald on rice in Togo, based on a comprehensive survey of 93 rice plots across 28 out of 39 prefectures. The research aimed to identify, characterize, and test the pathogenicity of fungi associated with leaf scald symptoms, as well as determine the disease's distribution and severity in Togo. Samples were collected, processed in the laboratory, and cultured using blotting paper and potato dextrose agar media. Results revealed that 97,84% of surveyed plots exhibited symptoms related to leaf scald and severity of the disease record were most 5 except two plots which were recorded 9 on the scale of 1 to 9. Fungal isolates were confirmed as R. oryzae through macroscopic and microscopic analysis, adhering to criteria described in existing literature. Growth of mycelium where about 7,5 days in 90 mm petri dish from both paper blotting and PDA medium from initiative culture. Sporus where two or three septa and were obtained after 9 days. Koch's postulates were fulfilled by reproducing leaf scald symptoms using the isolated fungi on the variety IR 841 at 50 days stage. This study contributes valuable insights into the prevalence and characteristics of leaf scald in Togolese rice field.
The Facilitating Factors of Organizational Learning in Pharmaceuticals Sector of Bangladesh
Authors: Akter Farzana
Published: September 2024

The present study is focused on the determinant factors of the organizational learning culture in pharmaceutical companies. The work explains the role of leadership, employee engagement, training, and knowledge-sharing mechanisms. The main purpose of the study is to explore four companies and determine to what extent learning culture and various elements impact it. The paper describes the survey conducted with 200 respondents working for these entities. The employees had different experience and occupied diverse positions. The analysis was completed with the help of 20 key areas. Correlation analysis, ANOVA, T-tests, factor analysis, and regression models were used to identify relationships. The results are compared in such aspects as leadership support, training opportunities, and innovation encouragement. It has been determined that both leadership and the so-called culture of continuous learning are the main factors that might affect an employee’s ability to apply the new knowledge. The correlation between leader engagement and the ability to use knowledge is average. Factor analysis shows that management performance could be attributed to five dimensions, which are related to leadership, training, feedback mechanisms, innovations, and sharing practices. Finally, regression analysis reveals that such culture of learning could be regarded as the best predictor of whether an employee will apply knowledge. Interestingly, these factors are not significantly different in such departments as leadership and non-leadership. Similar improvements are observed among different departments.
Elastomeric Toothbrushing Aid to Improve the Toothbrushing Skills of Children with Disabilities
Authors: Elman Efzi Agno , Eko Ningtyas Endah Aryati , Fatmasari Diyah
Published: September 2024

Background: In 12 years old children with disabilities, 30.2% had caries and in 15 years old children it increased by 2.3%.Limited handgrip motor skills in children with disabilities is 0.09% 1.5-3% have such limitations which the incidence is related to socioeconomic status. Therefore, 80-90% of children require assistive devices to facilitate their handgrip motor activities. Objective: To produce a feasible and effective elastomeric tooth brushing aid to improve tooth brushing skills and reduce debris index in children with disabilities. Methods: The study used quasi experimental (pre-post with control group design). The sampling technique was purposive sampling, consisting of 11 children in the intervention group with the application of elastomeric tooth brushing aids and 11 children in the control group with the application of conventional adult toothbrushes, with the length of treatment given 10 days. By making elastomeric tooth brushing aids manually combining elastomeric materials on conventional toothbrush handles. Results: The results of expert validation of elastomeric tooth brushing aids showed a p-value of 0.104 which means that this model is feasible as an effort to improve tooth brushing skills in children with disabilities. This model is effective in improving the teeth brushing skills of children with disabilities (p = 0.041) and reducing the debris index score of children with disabilities (p = 0.000) and reducing the debris index score of children with disabilities (p = 0.000). Conclusion: Elastomeric tooth brushing aids are feasible and effective in improving tooth brushing skills and reducing the debris index of children with disabilities.
An Examination of Threats and Countermeasures Relating to Healthcare Cyber Risks: The Case of Kenyatta National Hospital
Authors: Okongo Ario Stephen , T. Anyango Jecton , John Jenu
Published: September 2024

Background Africa has seen an exponential increase in internet penetration and ICT affordances since the turn of the twenty-first century. Healthcare institutions are scrambling to put in place the appropriate safeguards to protect their patients' data from unauthorized access since the need to protect private information has become critical, particularly for cybercriminals eyeing the data of medical patients. This thesis investigates cyber security threats and countermeasures in healthcare, with a focus on Kenyatta National Hospital (KNH). Given Africa's increased internet use and the critical need to protect patient data from cybercriminals, the study explores how data protection and cyber security influence healthcare delivery at the hospital.  Key Objectives To examine cyber threats and countermeasures employed by KNH as well as analyzing the impact of Kenya's Cybercrime Act.  Results The survey at Kenyatta National Hospital shows strong cybersecurity measures, with 89% having dedicated resources and 88% using computers regularly. Regarding the Kenya Cybercrime Act, 74% know how to detect and report hacks, though 8% have encountered malware and 12% lack basic malware knowledge. 78% have anti-virus software, and 63% verify email attachments, while knowledge of social engineering and email scams is limited, revealing a need for further education. The second objective looked at the impact of Kenya Cybercrime Act, as a local data protection laws on supporting patient- healthcare system at Kenyatta National Hospital. A significant majority, 74%, are aware of when their computer is hacked or infected and know whom to contact in such cases. The results also show that 79% of respondents have never encountered a virus or trojan on their computers. When opening email attachments, 63% of respondents always verify that the attachment is from a known and expected source. Knowledge of social engineering attacks is limited, with only 18% of respondents aware of these threats and 82% unfamiliar with them. Regarding email scams, 51% do not know what an email scam is or how to recognize one, underscoring a need for further training. Finally, while 85% of respondents believe their computers are not valuable to hackers, 15% recognize their potential as targets, reflecting differing perceptions of risk and emphasizing the need for ongoing cyber security education.
Directional Sound Field and Spatial Speech Decay: Impact of Sound Absorption and Screen Height in Performance Spaces and Open-Plan Offices
Authors: Samuel Agbeniyi Olalekan , Olaosebikan Rotimi
Published: September 2024

This study investigates the spatial decay rate of speech in performance spaces and open-plan offices, focusing on the effects of sound absorption and screen height. Utilising parameters such as D2, SD_2, SD2, S (decay rate) and Lp, A, S, 4mL_p, A, S, 4mLp, A, S, 4m (sound pressure level at 4 meters), the research evaluates how acoustic environments impact speech transmission. Through detailed experiments on different screen heights (1.2 m, 2.1 m, and 2.9 m) and material absorption, it was found that increasing screen height significantly reduces the spatial speech decay in open-plan offices, but only up to a certain threshold. The results suggest that while acoustic enhancements like screens and absorptive materials improve speech privacy, over-reliance on single- number ratings can lead to misclassification of office acoustics. This research provides insights for optimising room acoustics, ensuring speech privacy, and meeting acoustic comfort standards.
Bias and Fairness in AI Models: How can Bias in AI Models be Identified, Mitigated, and Prevented in Data Science Practices?
Authors: Jani Basha Shaik Mohammad , Kulkarni Aditya , Choudhary Subhangi , Lokesh Reddy Manognya
Published: September 2024

Artificial intelligence (AI) and machine learning (ML) systems are progressively used in different areas, going with basic choices that influence individuals' lives. In any case, these frameworks can sustain and try and fuel existing social predispositions, prompting uncalled for results. This paper looks at the wellsprings of predisposition in simulated intelligence models, assesses current methods for distinguishing and relieving inclination, and proposes an extensive structure for creating more pleasant simulated intelligence frameworks. By coordinating specialized, moral, and functional points of view, this exploration plans to add to a more evenhanded utilization of computer-based intelligence across various areas, guaranteeing that artificial intelligence driven choices are fair, straightforward, and socially dependable.
Relationship between Complementary use of Herbal Medicines and Diabetes Mellitus Treatment Outcomes: A Cross-Sectional Study in Two Tertiary Healthcare Facilities in Jos Metropolis
Authors: DAVID Shalkur , Oluwadamilola ONI Christiana , EJILA Byenchit , Naankut ALPHONSUS Peter , Alex DAYOL Meshak Simeon
Published: September 2024

In Nigeria, the use of herbal medicines to complement diabetes treatment is common, though their impact on treatment outcomes is not well understood. This cross-sectional questionnaire study, conducted in Jos metropolis, Nigeria, assessed the prevalence of herbal medicines use among 141 diabetes patients and its relationship with treatment outcomes. Most of the study participants were females (60.3%) with a family history of diabetes (70%). The findings showed that 58.9% of participants used herbal remedies like Moringa oleifera, Vernonia amygdalina and Allium sativum to complement treatment for diabetes mellitus without guidance from conventional clinicians. There were higher incidences of hospitalizations and hypoglycemia in the group that complemented their treatments with herbal medicines (P <0.05). However, fasting blood glucose levels remained unaffected (P > 0.05). The study highlights the common use of herbal medicines in Nigeria and underscores both the prospect for herbal medicine integration and the challenges of poor clinical data to inform ration use.
Explicit estimates of the number of distinct prime divisors of binomial coefficients
Authors: Berkane Djamel , Sadaoui Boualem , Dusart Pierre
Published: September 2024

UDC 511
We propose explicit estimates of the number of distinct prime divisors of a binomial coefficient through the explicit generalizations of some principal existing results. We also prove interesting number-theoretical propositions for  the terms of a sequence of primes.
Mittag-Leffler stability and stabilization of some classes of time-varying fractional systems
Authors: Omri Faouzi
Published: September 2024

UDC 517.9
We consider some classes of  time-varying fractional systems and  study the problem of stabilization for these systems with  norm-bounded controls. We use time-varying Lyapunov functions to analyze the Mittag-Leffler stability of these systems.  A numerical example is given to illustrate the efficiency of the obtained result.
A generalization for the kinematics of sliding-rolling motion in the semi-euclidean space

ℝ
ε
3
Authors: Şahin Tevfik , Orbay Keziban , Özdemir Zehra
Published: September 2024

UDC 531
We propose a generalization for the sliding-rolling motion, which leads to meaningful physical and mathematical results as the general metric includes the time dimension. We also investigate the kinematics of the relative motion of two rigid objects, which maintain sliding-rolling contact, by using the general adjoint approach in the semi-Euclidean space 

ℝ
ε
3

,

where

ε
∈

{
0,1
}

.

 This generalization gives  the geometric kinematic equations of the sliding-rolling motion in Minkowski and Euclidean spaces. In these spaces, we get a set of overconstrained equations. Solving this system, we determine translational and angular velocities of the moving surface.
 Finally, we illustrate the results by two examples.
Fostering the resilience of HEIs by the introduction principles of education for sustainable development: a pilot study
Authors: Dehtjare Jevgenija , Kinderis Remigijus , Mironova Julija , Užule Kristīne , Hanushchak-Yefimenko Liudmyla
Published: September 2024

The purpose of this study is to investigate validity of the survey, used to research how introduction of education for sustainable development (ESD) principles into the process of higher education may foster the resilience of higher education institutions (HEIs). The scope of investigation lies within priorities of sustainable development goals (SDG), SDG 4 – quality education in particular and within the impact of ESD to overall sustainable transformation of the modern world in the challenging conditions. The tasks of the study are to identify, after a thorough analysis of the factors that determine the implementation of the principles of the ESD in higher education, how its introduction may foster the resilience of higher education institutions. Methods employed in this research includes literature review, survey and it’s statistical interpretation. The final results show the importance of the survey questions given to the academic staff of HEIs in an order to determine the priority of study process administrative change in consonance with the ESD principles.
Contribution to the floristic knowledge of Mount Pennino massif (Umbria-Marche Apennines, central Italy)
Authors: Tardella Federico M. , Pennesi Riccardo , Ballelli Sandro , Cancellieri Laura , Caruso Giuseppe , Falcinelli Francesco , Fascetti Simonetta , Galasso Gabriele , Gigante Daniela , Laface Valentina L. A. , Lattanzi Edda , Lavezzo Paolo , Musarella Carmelo M. , Pinzani Lorenzo , Quattrini Giacomo , Rosati Leonardo , Spada Francesco , Stinca Adriano , Tilia Agnese , Catorci Andrea
Published: September 2024

The inventory of the taxa collected in 2021 during the annual field trip of the Working Group for Floristics, Systematics, and Evolution of the Italian Botanical Society is reported. The field trip was held in the Mount Pennino massif, between Umbria and Marche administrative regions (central Italy). The flora documented for the study area amounts to 413 specific and subspecific taxa (including one hybrid), belonging to 234 genera and 64 families. Thirty-seven taxa are endemic to Italy; 42 are included in the IUCN Red List of the Italian Flora. Only three alien taxa were found. Ten taxa and one hybrid are considered floristic novelties because either new or confirmed for the regional flora of Umbria and/or Marche. Particularly, 6 taxa are new and 4 are confirmed for Umbria; one taxon and one hybrid are new for Marche.
Integrative taxonomy of a new species of a bumble bee-mimicking brood parasitic bee, Tetralonioidella mimetica (Hymenoptera, Apoidea, Apidae), investigated through phylogenomics
Authors: Orr Michael C. , Chesters Douglas , Williams Paul H. , Wood Thomas J. , Zhou Qingsong , Bossert Silas , Sless Trevor , Warrit Natapot , Rasmont Pierre , Ghisbain Guillaume , Boustani Mira , Luo A’rong , Feng Yuan , Niu Ze-Qing , Zhu Chao-Dong
Published: September 2024

A new species of bumble bee-mimicking brood parasitic bee, Tetralonioidella mimetica Orr & Zhu, sp. nov., is described from China. The systematic placement of this species was initially challenging but was resolved using a combination of phylogenomic and COI barcode analyses, which strongly support the new species as a member of the genus Tetralonioidella Strand. Interestingly, the new species mimics the color pattern of both a bumble bee (Bombus Latreille), and its host Habropoda Smith species, a mimicry format previously unknown for bees. A review of the other Tetralonioidella species revealed three additional bee mimics, including two further likely model-host-brood parasite mimicry complexes. To our knowledge, these represent the first documented three-tiered mimetic systems in bees. Several additional taxonomic actions recently became necessary in these and related taxa: Tetralonioidella meghalayensis Dohling & Dey, 2024 is synonymized syn. nov. with Habropoda radoszkowskii (Dalla Torre, 1896) and Varthemapistra Engel, stat. rev. is again synonymized with Habrophorula Lieftinck. Our results also highlight issues with the generic classification of the tribe Melectini as currently used, as Melecta Latreille was found paraphyletic in relation to the remaining melectine genera. As a first step toward resolving this issue, we return the Melecta subgenus Eupavlovskia Popov, stat. rev. to genus level and discuss the ongoing systematic uncertainties regarding melectine taxonomy.
Passer par l’Europe pour saisir des rapports au politique
Authors: de Lassalle Marine
Published: September 2024

Considérée comme lointaine, technique, affaire de spécialistes, l’Europe communautaire est peu étudiée par la sociologie politique – hormis lorsqu’elle est « européenne ». C’est pourtant pour toutes ses caractéristiques négatives que le passage par l’Europe constitue une voie particulièrement heuristique pour réinterroger des rapports au politique. Fondé sur la réanalyse d’entretiens réalisés en France lors de l’enquête CONCORDE (CONCeptions ORdinaires De l’Europe) entre 2005 et 2007, l’article porte plus délibérément l’attention sur ce que les enquêtés, en parlant de l’Europe, disent de ce que la politique en général signifie pour eux, en fonction de leurs positions et de leurs ressources sociales et relationnelles. Il explore la façon dont les entretiens livrent un certain nombre d’indices qui permettent de revenir sur cette diversité de rapports afin d’en proposer des pistes de compréhension, en analysant les substrats de leur construction institutionnelle et de leur cohérence sociologique. Ayant fait, dès lors, du rapport familier à la politique non plus un pôle d’un continuum réglé par la compétence, mais un rapport au politique parmi d’autres, cet article s’interroge ensuite sur le fait de savoir si la légitimité qui constituait ce rapport est toujours aussi indiscutée – façon d’interroger les transformations contemporaines de l’exercice ordinaire de la domination.
Les effets de champ dans la politique internationale
Authors: Pouponneau Florent
Published: September 2024

Une mise au travail du concept de champ international s’avère très utile pour saisir comment l’État se construit avec et contre d’autres États. Comme le montre une enquête sur l’intervention militaire de la France au Mali, la logique propre de ce champ – qui se manifeste sous la forme d’une division internationale du travail politique – contribue, même en dehors de toute interaction directe, à travers les espaces des possibles qu’elle offre en fonction de la position occupée en son sein, à façonner les représentations et les calculs des acteurs engagés, à former les institutions et les champs nationaux et, en définitive, à orienter le contenu et les résultats des politiques étrangères. Une telle analyse, du fait même des difficultés qu’elle soulève, pose des questions générales sur la place et la nature des effets de champ. Cet article souligne ainsi que l’observation d’effets de champ peut servir à construire la structure même du champ, dès lors que l’on entend éviter toute réification de cette dernière. Il avance également que les effets de champ sont plus étendus ou plus variés qu’on ne le pense habituellement. Enfin, il invite à la prise de distance avec l’empirie pour rompre avec tout raisonnement circulaire.
Un effet de champ bureaucratique
Authors: Groc Benjamin
Published: September 2024

Cet article propose d’analyser les effets de l’aide internationale sur le champ bureaucratique en Bolivie – un pays qui a considérablement réduit sa dépendance aux ressources financières et techniques apportées par les agences multilatérales et bilatérales de développement en l’espace de deux décennies. Durant les trois mandats de la présidence d’Evo Morales, entre 2006 et 2019, le retour de l’État dans le modèle de développement, ainsi que la réduction de l’espace occupé par les bailleurs de l’aide, ont transformé les administrations mais aussi les luttes entre les élites politiques et administratives au sein de l’État. S’interroger sur le caractère transnational du champ bureaucratique d’un État récipiendaire d’aide permet de saisir la manière dont les relations extra-nationales ont des effets structurants sur les luttes internes de ce champ. Pour cela, nous nous focalisons sur le vice-ministère à l’Investissement public et au Financement extérieur (VIPFE), une unité ministérielle en charge de la gestion de l’aide et des relations avec les bailleurs internationaux. Bien que plusieurs effets de champ se soient estompés avec la réduction de la part de l’aide dans le financement de l’État, l’imbrication des bailleurs dans le champ bureaucratique continue d’avoir des effets sur les trajectoires professionnelles des fonctionnaires ministériels, en particulier pour ceux issus du VIPFE.
Edith Stein au chevet de l’Europe
Authors: Bur Laurence
Published: September 2024

À l’heure où l’Union européenne fait largement face au scepticisme de ses habitants, mais où la guerre en Ukraine montre la nécessité d’être unis, de quelles ressources spirituelles l’Europe dispose-t-elle, qui puissent lui permettre de redevenir un espace d’espérance ? Edith Stein, sainte Thérèse-Bénédicte de la Croix, déclarée co-patronne de l’Europe il y a vingt-cinq ans, peut aider à ranimer le grand rêve de paix des fondateurs de l’Europe. Sa vie placée passionnément sous le signe de l’ouverture à l’autre et du dialogue, à la fois sur le plan de la quête philosophique et sur celui de sa vie de foi, profondément marquée par ses origines juives, fait d’elle une ressource spirituelle pour la construction de l’« Europe du dialogue » que le pape François a appelée de ses vœux lors de son discours au Conseil de l’Europe en 2014.
Le dépistage néonatal de maladies génétiques en France
Authors: Pettazzoni Magali , Zhao Fanny , Renoux Céline , Cheillan David
Published: September 2024

Le dépistage néonatal systématique des maladies rares, mais graves, est un programme national de santé publique débuté en France en 1972. Six pathologies sont aujourd’hui recherchées en France à partir de sang prélevé sur papier buvard : la phénylcétonurie, l’hypothyroïdie congénitale, l’hyperplasie congénitale des surrénales, la drépanocytose, la mucoviscidose et le déficit en acyl-CoA déshydrogénase des acides gras à chaîne moyenne. Cette dernière anomalie de la β-oxydation mitochondriale des acides gras a pu être ajoutée au panel grâce à l’acquisition de spectromètres de masse en tandem par les laboratoires en charge de ce dépistage. Ces équipements permettront, en 2023, l’extension du programme à sept autres erreurs innées du métabolisme en analysant simultanément des acides aminés et des acylcarnitines. Dans les années à venir et comme dans d’autres pays, le programme du dépistage néonatal français de maladies génétiques rares évoluera à la faveur des progrès technologiques et à l’amélioration des connaissances médicales et thérapeutiques.
Génotypage plaquettaire fœtal sur sang maternel, une avancée pour la prise en charge de l’allo-immunisation fœto-maternelle
Authors: Petermann Rachel
Published: September 2024

Le génotypage plaquettaire fœtal est essentiel pour le diagnostic des incompatibilités plaquettaires entre le fœtus et sa mère ainsi que pour la prise en charge de l’allo-immunisation fœto-maternelle qui se manifeste notamment par une thrombopénie fœtale et/ou néonatale pouvant aboutir à une hémorragie intracrânienne. Chez les Caucasiens, la grande majorité des thrombopénies fœtales et/ou néonatales est due aux quatre systèmes antigéniques plaquettaires humains (HPA-1,-3,-5 et -15). Longtemps réalisé à partir d’une amniocentèse, d’un prélèvement de trophoblastes ou d’une ponction de sang fœtal, aujourd’hui, le diagnostic prénatal repose sur la détection de l’ADN fœtal dans le plasma maternel par diverses techniques de PCR et par le séquençage de nouvelle génération. Le génotypage plaquettaire fœtal permet d’évaluer le risque de la grossesse, d’adapter la surveillance clinique et biologique, de décider l’instauration d’un traitement anténatal maternel le cas échéant et de proposer la voie d’accouchement la plus adaptée au regard du risque de la grossesse.
Félix d’Herelle, découvreur des bactériophages et inventeur de la phagothérapie
Authors: Dublanchet Alain
Published: September 2024

Félix d’Herelle (1873-1949) a été un biologiste exceptionnel. Sa découverte des bactériophages aura marqué le XX e siècle, tant en biologie qu’en médecine, et elle apparaît fondamentale aujourd’hui. Mais la filiation et la formation, mal connues du personnage, ont probablement contribué à le rendre injustement mésestimé par la communauté scientifique. Il a consacré sa vie à défendre ses idées et a parcouru le monde. De nos jours, il est encore pratiquement inconnu du grand public, alors qu’il a découvert les bactériophages il y a plus de cent ans, en 1917, et développé dès 1919 la phagothérapie utilisant ces virus de bactéries pour traiter les maladies infectieuses bactériennes. Pendant les deux décennies qui ont suivi, une grande partie de la communauté scientifique a contesté sa découverte et discrédité son application thérapeutique. Si le développement de la biologie moléculaire et la génétique moderne s’est appuyé sur les bactériophages, aujourd’hui, la phagothérapie apparaît comme une réponse aboutie au problème majeur de l’antibiorésistance.
Actualités sur la diphtérie, zoonose, à l’occasion du centenaire des anatoxines par Gaston Ramon
Authors: Philippon Alain
Published: September 2024

Après 10 ans passés dans la préparation peu gratifiante de sérums antidiphtérique, antitétanique, antigangréneux et antivenimeux, le vétérinaire Gaston Ramon a mis au point les anatoxines diphtérique et tétanique dès 1923. Son sens aiguisé de l’observation l’amena à tester le formol pour une meilleure conservation des sérums antitoxiques et finalement découvrir la floculation, le titrage in vitro des toxines et enfin leur inactivation (formol + chaleur) sans perdre leur pouvoir immunogène, ouvrant ainsi la voie des vaccins par anatoxines. Lors de l’injection de toxines aux chevaux, il nota que la présence d’un abcès générait une meilleure production d’antitoxines, y compris chez l’animal multivacciné. Ces observations allaient permettre d’autres découvertes capitales dont les adjuvants de l’immunité, les vaccinations associées et les rappels vaccinaux. Bien que le plus souvent cité, il n’obtint jamais le Prix Nobel de Médecine. Si la diphtérie reste très minoritaire dans les pays pratiquant la vaccination par anatoxine, elle est devenue une zoonose due à Corynebacterium ulcerans , transmise surtout par le chat et le chien et capable de synthétiser la toxine diphtérique véhiculée par un prophage.