bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular fusion events in carcinogenic organisms: a bioinformatics study for the detection of fused proteins between viruses, bacteria and eukaryotes.
Authors: Papakonstantinou Eleni , Diakou Kalliopi Io , Mitsis Thanasis , Dragoumani Konstantina , Bacopoulou Flora , Megalooikonomou Vasilis , Kossida Sophia , Chrousos George P , Vlachakis Dimitrios
Published: April 2022

Molecular fusion events have a prominent role in the initial steps of carcinogenesis. In this study, a bioinformatics analysis was performed between four organisms that are known to induce cancer development in humans: two viruses, Human Herpesvirus 4, and Human T-cell leukaemia virus, one bacterium, Helicobacter Pylori, and one trematode, Schistosoma mansoni. The annotated proteomes from these organisms were analysed using the SAFE software to identify protein fusion events, which may provide insight into protein function similarities and possible merging events during the course of evolution. Based on the results, five fused proteins with very similar functions were detected, whereas proteins with different functions that might act in the same molecular complex or biochemical pathway were not found. Thus, this study analysed the above four well-known cancer-related organisms with de novo bioinformatics programs and provided useful information on protein fusion events, hopefully leading to deeper understanding of carcinogenenesis.
Utility of extracellular vesicles as a potential biological indicator of physiological resilience during military operational stress
Authors: Beckner Meaghan E. , Conkright William R. , Sahu Amrita , Mi Qi , Clemens Zachary J. , Martin Brian J. , Flanagan Shawn D. , Ferrarelli Fabio , Ambrosio Fabrisia , Nindl Bradley C.
Published: April 2022

Extracellular vesicles (EVs) transport biological content between cells to mediate physiological processes. The association between EVs and resilience, the ability to cope with stress, is unknown. Using unbiased machine learning approaches, we aimed to identify a biological profile of resilience. Twenty servicemen (27.8 ± 5.9 years) completed the Connor Davidson Resilience (CD‐RISC) questionnaire and were exposed to daily physical and cognitive exertion with 48‐hr sleep and caloric restriction. Blood samples from baseline and the second day of stress were analyzed for neuroendocrine biomarkers impacted by military stress. EVs were isolated from plasma and stained with antibodies associated with exosomes (CD63), microvesicles (VAMP3), and apoptotic bodies (THSD1). Individuals were separated into high (n = 10, CD‐RISC > 90) and low (n = 10, CD‐RISC < 79) resilience. EV features were stratified by size, then down‐selected using regression trees and compared between groups. Diagnostic accuracy was assessed using receiver operating characteristic curves. Compared to low resilience, high resilience demonstrated a greater increase in variability of THSD1 local bright spot intensities among large‐sized EVs in response to stress (p = 0.002, Hedges’ g = 1.59). Among medium‐sized EVs, high resilience exhibited a greater decrease in side scatter intensity (p = 0.014, Hedges’ g = 1.17). Both features demonstrated high to moderate diagnostic accuracy for high resilience (AUC = 0.90 and 0.79). In contrast, neuroendocrine biomarker concentrations were similar between groups. The increase in variability among THSD1 + EVs in high, but not low, resilient individuals following stress may suggest high resilience is accompanied by stress‐triggered apoptotic adaptations to the environment that are not detected in neuroendocrine biomarkers.
Impact of environmental toxicants exposure on gut-brain axis in Parkinson disease
Authors: Olubodun-Obadun Taiwo G. , Ishola Ismail O. , Adeyemi Olufunmilayo O.
Published: April 2022

Parkinson disease (PD) is a major public health challenge as many of the current drugs used in its management provide symptomatic relieve without preventing the underlying cause of the neurodegeneration. Similarly, the non-motor complications of PD, especially the gastrointestinal tract (GIT) disturbance increases the disease burden on both the PD patient and caregivers. Different theories have been postulated regarding the mechanisms or pathways involved in PD pathology but gut-brain axis involvement has gained much more momentum. This pathway was first suggested by Braak and colleagues in 2003, where they suggested that PD starts from the GIT before spreading to the brain. However, human exposure to environmental toxicants known to inhibit mitochondrial complex I activity such as rotenone, paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) are well associated with PD. Several reports have shown that oral exposure of laboratory animals to rotenone causes mitochondria dysfunction, GIT disturbance, overexpression of alpha synuclein and microbiota imbalance. This review focuses on the mechanism(s) through which rotenone induces PD pathogenesis and potential for therapeutic small molecules targeting these processes at the earliest stages of the disease. We also focused on the interaction between the GI microbiota and PD pathology.
Internal Variables as a Tool for Extending Navier-Stokes Equations
Authors: Berezovski Arkadi
Published: April 2022

The formalism of the internal variable theory is applied to extend Navier-Stokes equations. The internal variable theory provides a thermodynamically consistent derivation of constitutive relations and equations of motion without a priori specifying the nature of internal variables. Both single and dual internal variables cases are thoroughly examined. The similarities and differences of the approaches are emphasized. In the single internal variable framework, the elimination of the internal variable results in Maxwell-type constitutive relations and hyperbolic equations of motion. The dual internal variable technique enables us to create even more sophisticated fluid flow models with coupled equations for fluid motion and internal variable evolution.
Excellent perinatal outcome of monoamniotic twin pregnancy with timely diagnosis and optimal management – a retrospective cohort study
Authors: Stefanovic Vedran , Nupponen Irmeli , Jernman Riina Maria
Published: April 2022

Objectives

Monoamniotic twins represent a high-risk pregnancy requiring intense follow-up, elective birth and careful consideration of the mode and timing of delivery. We conducted this study to evaluate the perinatal and neonatal outcomes of monoamniotic twin pregnancies in the largest tertiary hospital in Finland.

Methods

This was a retrospective cohort study including all monoamniotic twin pregnancies during a 17-year period (2002–2018) managed in Helsinki University Hospital. Data on mothers and children were collected from patient files. Chorionicity and amnionicity were defined in first-trimester ultrasound screening.

Results

There were altogether 31 monoamniotic twin pregnancies during the study period, including four cases of conjoined twins which all underwent termination of pregnancy, and three miscarriages. In the remaining 24 pregnancies that continued past 24 weeks of gestation there was 97.9% survival (one intrauterine death). Three pregnancies were complicated with twin-to-twin transfusion syndrome. All children were delivered by cesarean section with a mean gestational age of 32 + 5 weeks (27 + 1–34 + 2 weeks). Respiratory distress syndrome (RDS) was observed in 57% (27/47) of neonates and grade I–II intraventricular haemorrhage (IVH) in 6.3% (3/47) of neonates. There were no neonatal deaths and no maternal complications.

Conclusions

Monoamniotic twinning is a rare form of pregnancy and carries risks for perinatal and neonatal complications. With timely diagnosis, close monitoring in specialized feto-maternal unit and elective delivery at 32–34 weeks the outcome is usually excellent.
Hydroxypropyl methylcellulose films reinforced with cellulose micro/nanofibrils: study of physical, optical, surface, barrier and mechanical properties
Authors: Mascarenhas Adriano Reis Prazeres , Scatolino Mário Vanoli , Santos Allan de Amorim dos , Norcino Laís Bruno , Duarte Paulo Junio , Melo Rafael Rodolfo de , Dias Matheus Cordazzo , Faria Caik Elisio Tonelli de , Mendonça Maressa Carvalho , Tonoli Gustavo Henrique Denzin
Published: April 2022

The accumulation of petroleum products causes damage to ecosystems, which can be avoided with cellulose-based products. The influence of different ratios of cellulose micro/nanofibrils (MFC/NFC) on the properties of hydroxypropyl methylcellulose (HPMC) films was evaluated. Films were prepared using proportions of 0, 25, 50, 75 and 100 % (w/w) of MFC/NFC from Pinus sp. in relation to HPMC. Physical, barrier, surface, optical, morphological and mechanical properties were evaluated. Solids content, basis weight and density values increased with higher amount of MFC/NFC and thickness and porosity were reduced. SEM images showed that films with more than 50 % MFC/NFC had a more granular surface, which decreased transparency from 80 to 65 %. Water vapor penetration did not differ between films and degradation in water was reduced from 40 to 5 % with MFC/NFC addition. There were no differences in contact angle and wettability, but all films showed high resistance to fat penetration. Films with MFC/NFC content between 75 and 100 % showed higher values for tensile strength (50 to 65 MPa) and Young’s modulus (6 to 10 MPa) and lower elongation at break (1 to 2 %). The experimental results indicated that films with MFC/NFC content above 50 % have potential to be used as packaging material.
ExcelAutomat 1.4: generation of supporting information
Authors: Laloo Jalal Z. A. , Savoo Nandini , Rhyman Lydia , Ramasami Ponnadurai
Published: April 2022

Quantum chemical computations generate output files with data. The processing of these data generates results which are presented in a target document, such as a manuscript or supporting information (SI). Several tools and techniques can be employed to facilitate the transfer of data which, otherwise, can be time-consuming with a large number of files. However, depending on the user’s technical knowledge or expertise with the software, additional time has to be invested to set up the software or use the tools. In addition, to the best of the authors’ knowledge, the tools currently available do not provide an option to transfer the data from the output files directly to the target document without the use of custom scripts. The ExcelAutomat tool (Laloo et al., J. Comput. Aided Mol. Des. 2017, 31, 667 and Laloo et al., J. Comp. Chem. 2019, 40, 3) is spreadsheet-based and was developed in-house to facilitate the steps involved in the processing of computational files. The tool was adapted to facilitate the generation of SI in an update of ExcelAutomat 1.4. A graphical user interface was designed where the options for the generation of SI can be defined. ExcelAutomat 1.4 is compatible with Microsoft Excel and the open-source LibreOffice Calc. The extensible tool supports various software packages and parameters by interfacing with the cclib library and through built-in codes. The tool provides a method to transfer data from output files directly to a Microsoft Word or LibreOffice Writer document and can reduce the number of steps, tools or technical knowledge needed to generate SI, especially for users who are familiar with Microsoft Excel or LibreOffice Calc.
A novel theranostic probe [111In]In-DO3A-NHS-nimotuzumab in glioma xenograft
Authors: Tang Yu , Liao Zhonghui , Li Feize , Liu Weihao , Gao Jing , Li Yuhao , Hu Yingjiang , Cai Huawei , Ma Huan , Yang Yuanyou , Yang Jijun , Liao Jiali , Liu Ning
Published: April 2022

Indium-111 (111In) has an appropriate half-life (T
1/2 = 67 h) and energy characteristics for cancer diagnosis via γ-ray imaging and cancer therapy with Auger electrons. The aim of our study is to evaluate the potential of [111In]In-DO3A-NHS-nimotuzumab as a theranostic agent for radioimmunoimaging (RII) and radioimmunotherapy (RIT) against human glioma xenografts in mice. We explored the chelators DO3A-NHS and DOTA-p-SCN-Bz to optimize 111In radiolabeling efficiency of nimotuzumab. The radiopharmaceuticals were purified by PD-10 mini-column and their in vitro stabilities were assessed. We investigated the biodistribution of [111In]In-DO3A-NHS-nimotuzumab as it had relatively superior labeling efficiency and stability in vitro. We conducted SPECT imaging on mice bearing glioma (U87MG) xenografts, which were injected with ∼3.7 MBq of [111In]In-DO3A-NHS-nimotuzumab. The in vivo radiotherapeutic effects of [111In]In-DO3A-NHS-nimotuzumab was analyzed via injecting a single 37 MBq dose, 2 × 18 MBq doses, or 2 × 37 MBq doses into mice bearing U87MG xenografts. The control groups were administered either 30 μg nimotuzumab or saline. The radiochemical yields of [111In]In-DO3A-NHS-nimotuzumab and [111In]In-DOTA-p-SCN-Bz-nimotuzumab were > 85% and > 75%, respectively. [111In]In-DO3A-NHS-nimotuzumab had > 95% radiochemical purity and was more stable in vitro than [111In]In-DOTA-p-SCN-Bz-nimotuzumab. Biodistribution study demonstrated that [111In]In-DO3A-NHS-nimotuzumab was highly stable in vivo. SPECT imaging disclosed that [111In]In-DO3A-NHS-nimotuzumab had excellent targeted tumor uptake and retained in tumors for 24 and 72 h. All [111In]In-DO3A-NHS-nimotuzumab treatments substantially inhibited tumor growth over the controls. The 2 × 37 MBq treatment was particularly efficacious, and presented with survival time prolonged by ≤66 days. In contrast, the survival time of the control group was only 30 days. In our study, we developed an optimized synthesis protocol for radiopharmaceutical 111In-DO3A-NHS-nimotuzumab and demonstrated that it is a promising theranostic agent. It could be highly efficacious in RII and RIT against EGFR-expressing glioma.
Especies de Carangidae inusuales durante el Niño costero 2017 en el litoral de Pisco, sur del Perú
Authors: Donayre-Salazar Susan , Higaki Moyano Keichi , Roque-Sánchez Máximo , Lorenzo Alberto , Barriga Rivera Edward
Published: April 2022

Este trabajo reporta la presencia inusual de especies de la familia Carangidae en los desembarcaderos de la provincia de Pisco (13.5° S), departamento de Ica, ocurridos durante el evento El Niño costero 2017. Se observaron 4 especies: Caranx caballus, Caranx caninus, Oligoplites saurus y Selene brevoortii capturadas con el arte de pesca “cortina agallera”. Durante el periodo de El Niño costero 2017 en el área de estudio se registraron temperaturas superiores a los 26 °C y salinidades moderadamente elevadas (> 35.1 ups), condiciones que habrían favorecido el desplazamiento de estas especies, frecuentes en el norte del Perú, hacia latitudes superiores.
GEOCHEMICAL TRANSFORMATION OF ENVIRONMENTAL OBJECTS WITHIN SOLID WASTE LANDFILLS (ON THE EXAMPLE OF KYIV)
Authors:   M.P. Semenenko Institute of Geochemistry, Mineralogy and Ore Formation of the NAS of Ukraine, Kuraieva I.V. , Koshliakova T. , Azimov O. , Zlobina K. , Khrushchov D.
Published: April 2022

The presented research is devoted to the study of geochemical transformation of environmental key objects (soils, surface and groundwater) within the solid waste landfills. The object of the study is the one of the largest landfills for solid waste disposal in Ukraine – Kyiv landfill №5. The main factual material, which is the basis of the article, was obtained by the authors during a comprehensive field ecological and geochemical research in 2018-2020. The aim of the work was to determine the geochemical (in particular physical and chemical) features of soil sediments within the landfill, which made it possible to assess the protective properties of soils in relation to the impact of technogenic metals. The condition of surface waters (ponds within the landfill territory) and groundwater (wells in Pidhirtsi village) was also studied; the comparison of the main indicators of chemical composition with the maximum allowable concentrations determined by normative documents was performed. It was found that in the studied soils there is a high concentration of heavy metals associated with the fraction of easily exchangeable ions, as well as an increased content of water-soluble forms. The main migration forms of macro- and microelements in soil solutions have been established. It was found that free hydrated cations and metal-organic complexes are characteristic of heavy metals. For groundwater used for potable water consumption by the population of Pidhirtsi village, exceeding of maximum allowable concentrations were recorded for certain indicators, in particular for nitrates, as well as deviations from the established norms for Ba, SO4, Fe, Mn, Co, Ni, Mo, and Pb. The pond waters, located directly within the landfill territory, are characterized by significant deviations from the norm in terms of Fe, Mn, Ni, Ti, V, Cu and Zn. As a result of the study, it was found that within the landfill there are favorable conditions for the formation of mobile forms of toxic elements and their migration to surface and groundwater
MEDIA RETORIKA DAKWAH PADA ERA MILENIAL
Authors: Trilaksono Bobby H. , Prasetyawan Wahyu , Amirudin Amirudin , Rizky Kiky
Published: April 2022

Media retorika menjadi sebuah seni yang dapat membantu tercapainya proses komunikasi dan mempengaruhi orang lain untuk menerima isi pesan yang disampaikan. Retorika dakwah merupakan poin penting yang dibutuhkan dalam menyampaikan sebuah isi pesan dakwah yang diberikan kepada manusia. Penerapan retorika dakwah dapat membantu tercapainya tujuan dakwah yang diinginkan. Setiap orang akan memiliki kesempatan yang sama untuk bisa menyampaikan dakwah di era milenial seperti saat ini. Adanya penerapan seni berbicara yang mampu diterima dengan mudah oleh para khalayak. Di era milenial masyarakat telah mengalami perubahan pada pola hidup di mana segala sesuatunya didampingi dengan penggunaan teknologi digital. Manusia serasa tidak bisa hidup tanpa adanya teknologi digital yang kini dapat membantu terpenuhinya kebutuhan yang dimiliki. Tentunya, dakwah akan bisa dilakukan dengan baik dan mampu mempersuasi penerima pesan saat dilakukan dengan memanfaatkan teknologi digital. Kini dakwah dapat dilakukan dan disebarkan melalui beragam media sosial seperti WA, Facebook, internet, Instagram, Youtube, Twitter, dan media lainnya.Kata Kunci: media retorika, dakwah, era milenial.
FASE TRANSFORMASI IDEOLOGI PERTUNJUKAN TEATER KANVAS
Authors: Makki Nur Kholis , Qoyim Ibnu
Published: April 2022

Penelitian ini berbentuk penelitian kualitatif dengan menggunakan pendekatan etnografi yang bertujuan untuk melihat bagaimana proses transformasi ideologi pertunjukan pada salah satu kelompok Teater di Jakarta, yaitu Teater Kanvas. Dalam penelitian ini peneliti menggunakan data wawancara, naskah pertunjukan dan beberapa kliping pemberitaan seputar pertunjukan, ataupun pemberitaan eksklusif tentang Teater Kanvas yang diambil pada Oktober 2019 hingga Juli 2020. Setelah memperoleh data dari naskah, dokumentasi, kliping berita dan wawancara, langkah selanjutnya adalah mengklasifikasikan data sesuai  dengan  permasalahan  yang diteliti,  kemudian  data  tersebut  disusun, dianalisis dan dikelompokkan. Hasil penelitian ini adalah proses transformasi Ideologi pertunjukan Teater Kanvas yang terdiri dari tiga fase, yaitu; fase ideologi pertunjukan awal, fase transisi ideologi pertunjukan dan fase ideologi baru pertunjukan Teater Kanvas.Kata Kunci: teater, transformasi, pertunjukan, ideologi
IMPLEMENTASI TEORI KOMUNIKASI DALAM PENGGUNAAN TRADISI LISAN LAWAS PAMUJI PADA MASYARAKAT SUKU SUMBAWA
Authors: Natasari Nofia , Marhandra Roy
Published: April 2022

Tradisi Lisan Lawas Pamuji masih melekat dalam kehidupan sosial masyarakat Sumbawa. Pesan-pesan yang disampaikan sebagai motif menggugah kesadaran masyarakat untuk meningkatkan keimanan. Keberlangsungan penggunaan Lawas Pamuji di tengah-tengah masyarakat di ekspresikan oleh para pegiat seni dan para pendakwah dalam berbagai metode, dan produk karya seni tradisi. Lawas Pamuji yang hingga hari ini masih dapat kita temukan di dalam kehidupan masyarakat, tentu menjadi pertanyaan di dalam benak kita bagaimana komunikasi yang berlangsung di dalam masyarakat Sumbawa sehingga proses penyaluran, pewarisan kepada generasi selanjutnya. Untuk menganalisis hal tersebut, peneliti menggunakan teori komunikasi model Harold Laswell. Sementara untuk memahami dan memudahkan peneliti dalam mengurai apa saja komponen komunikasi dalam Lawas Pamuji, dengan menggunakan teori tradisi lisan Albert Lord. Hasil yang ditemukan di dalam penelitian tersebut adalah, bahwa proses komunikasi yang berlangsung di dalam penggunaan Lawas Pamuji pada masyarakat Sumbawa telah memberikan dampak kepada perubahan sikap dan bertambahnya ilmu pengetahuan. Hal tersebut dapat ditunjukkan dalam operasional komponen komunikasi Lawas Pamuji dalam kehidupan masyarakat suku Sumbawa.Kata Kunci: komunikasi, lawas pamuji, suku sumbawa
KOMUNIKASI, TEKNOLOGI INFORMASI DAN KETENAGA KERJAAN KAJIAN PERKEMBANGAN INKLUSI TEKNOLOGI DIGITAL DAN PENGANGGURAN DI INDONESIA
Authors: Soniansih Seni , Kusmiati Yopi , Humeira Bintan
Published: April 2022

Inovasi teknologi dikhawatirkan menyebabkan pengangguran massal. Namun Inovasi teknologi juga dibutuhkan dalam mendorong pertumbuhan ekonomi. Tujuan makalah ini adalah memahami dan meramalkan dampak inovasi teknologi terhadap tenaga kerja di Indonesia dengan pendekatan model John Hick yang di estimasi menggunakan model Threshold Autoregressive (TAR). Penelitian ini berusaha mengkontruksi dan memetakan dampak inovasi teknologi pada ketenaga-kerjaan serta mencari solusi mengatasi dilema inovasi teknologi dan ketenaga kerjaan dan mengkombinasi dengan metode kuantitatif content analysis.Kami menemukan bahwa inovasi teknologi  memiliki pengaruh terhadap ketenagakerjaan,potensi pembukaan peluang kerja baru sebagai dampak positif inovasi teknologi sebagai kompensasi penekanan kesempatan kerja akibat inovasi teknologi.Kata Kunci :  Indonesia, Pengangguran, Inovasi, Teknologi.
Questions and Answers
Authors: Thompson Lee
Published: April 2022

Questions on the 2001 changes to CPT critical care codes
Coding Basics: Observation Codes
Authors:   American Academy of Pediatrics
Published: April 2022

Observation codes
Questions and Answers
Authors:   American Academy of Pediatrics
Published: April 2022

Questions on coding for accidental poisoning, counseling the family (child not present), pelvic examinations, use of EMLA, and covering for another pediatrician
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Which code to use for a baby with a large head, using codes 769 and 770.8, and the differences between a referral and a consultation: the 3 Rs
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Answers to common coding questions from the AAP Coding Hotline
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Coding for OAE screening (code 92587)
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Neonatal coding
Denial Den
Authors:   American Academy of Pediatrics
Published: April 2022

Appealing denials when using codes 31500, 36510, and 36660
Practice Management Tip
Authors:   American Academy of Pediatrics
Published: April 2022

Information on Excluded Entities/Individuals
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Using 2 E/M services codes for care provided to a child the same day
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Sharpen your skills for using codes 99211-99215
Modify What?
Authors:   American Academy of Pediatrics
Published: April 2022

How/why to use modifiers and examples of category 1 modifiers
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Covers venipuncture, removing an extra digit, peak flow, and the new Td vaccine
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Practice coding for developmental and behavioral services
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Services provided to twins by multiple physicians
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Consultation for a neonatologist prior to birth
Q&A (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting initial hospital care services, near-SIDS or ALTE, and chief complaint
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Creating a care plan for a patient with diabetes
You Code It! (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting home visit services
Q&A (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

CPT codes for palliative care in the NICU, consulting on end-of-life planning, coordination of care in the home, and ICD-9-CM codes for chronic aspiration, unrelated conditions, and limits to diagnosis codes on a claim
Have You Noticed These 2007 Current Procedural Terminology (CPT®) Code Changes? (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Important changes and additions for 2007: consultation, continuous inhalation, pulmonary stress testing, nitric oxide expired gas determination, lesion removal, and genetic counseling.
Q&A (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Detailed coding guidelines for referrals, removal of foreign bodies, and blood tests
Coding for Synagis (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Coding for Synagis (palivizumab), an immunoglobulin, differs from coding for vaccines and toxoids
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Help with coding for burns, nasal congestion, and splints
Denial Den (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Advocating for correct vision and hearing screening codes
Subspecialty Corner: Ventilator Management
Authors:   American Academy of Pediatrics
Published: April 2022

Four new CPT codes that more accurately describe ventilator management services
Modifier 52 or 53?
Authors:   American Academy of Pediatrics
Published: April 2022

Distinct differences between modifier 52 (reduced services) and modifier 53 (discontinued procedure)
Coding Hydration, Therapeutic, Prophylactic, and Diagnostic Injections and Infusions When Performed in the Emergency Department
Authors:   American Academy of Pediatrics
Published: April 2022

Proper coding of hydration, therapeutic, prophylactic, and diagnostic injections and infusions performed in the emergency department
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Preterm drug exposure, home visits, intoeing, pertinent history, and covering for another physician
You Code It! (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

An office encounter and subsequent hospital admission the same day
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Developmental delay due to drug exposure as a fetus, chemical exposure, adhesion of the foreskin, laceration of the ear canal, altered mental status, and elevated lead
Denial Den
Authors:   American Academy of Pediatrics
Published: April 2022

Denial management and negotiation for hearing screening
Current Dental Terminology Codes
Authors:   American Academy of Pediatrics
Published: April 2022

Codes for dental prophylaxis and other dental preventive services and counseling
Consultations
Authors:   American Academy of Pediatrics
Published: April 2022

Requirements for a consultation
CPT Code Changes for 2008
Authors:   American Academy of Pediatrics
Published: April 2022

Changes to procedure codes effective January 1, 2008
Coding for Albuterol
Authors:   American Academy of Pediatrics
Published: April 2022

New coding for albuterol for services provided on or after July 1, 2007, replacing J7611-J7614
A Special Issue: Get Paid for Vaccines and Immunization Administration
Authors:   American Academy of Pediatrics
Published: April 2022

Help preserve effective and efficient payment for vaccine services
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting administration of Tdap instead of DTaP vaccine
Practice Management Tips and Resources
Authors:   American Academy of Pediatrics
Published: April 2022

Resources available to practices for vaccines and immunization payment benefits, vaccine purchasing strategies, and vaccine registries
Commonly Administered Pediatric Vaccines/Toxoids and Immune Globulins (2008)
Authors:   American Academy of Pediatrics
Published: April 2022

CPT and ICD-9-CM codes for commonly administered vaccines/toxoids and immune globulins
You Code It! The Answers (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

The Answers: Reporting observation of counseling via one-way-mirror
The Facts About Reporting Developmental Testing
Authors:   American Academy of Pediatrics
Published: April 2022

Dispelling myths about how to report developmental testing
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Effects of revisions to modifiers 22 and 59, reporting a meeting at a patient’s school, and septo-optic dysplasia
The New V Code Table
Authors:   American Academy of Pediatrics
Published: April 2022

New easier reporting sequence for V codes
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Questions: Reporting of AUDIT alcohol disorder test and intervention plan discussion
Reporting Cardiovascular Services
Authors:   American Academy of Pediatrics
Published: April 2022

New codes and revisions for cardiovascular services
Coding Challenge: How Should You Report Medical Team Conferences for Patients Receiving Inpatient Critical or Intensive Care?
Authors:   American Academy of Pediatrics
Published: April 2022

Surmounting the paradox in medical team conference reporting
Codes for Albuterol Change—Once Again!
Authors:   American Academy of Pediatrics
Published: April 2022

Reinstating codes J7611-J7614 for reporting albuterol and levalbuterol provided on or after April 1, 2008
Denial Den
Authors:   American Academy of Pediatrics
Published: April 2022

Using codes 99050-99060 for after hours E/M services
New Codes to Report Remote Critical Care Services
Authors:   American Academy of Pediatrics
Published: April 2022

Two new remote critical care codes effective July 1, 2008 for remote real-time interactive videoconferenced critical care
Get Ready for Major Changes to CPT 2009 for Reporting Neonatal Services!
Authors:   American Academy of Pediatrics
Published: April 2022

Preview of reorganization, renumbering, and new codes for Neonatal E/M Services for 2009, to be fully discussed in the 11/08 issue
Will I Get Paid for This Vaccine?
Authors:   American Academy of Pediatrics
Published: April 2022

Timing of AMA code changes and FDA approvals for vaccine administration
New Place of Service Code
Authors:   American Academy of Pediatrics
Published: April 2022

New code 16 for services provided in a temporary lodging
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Low milk supply and postnatal depression
Access to AAP Pediatric Coding Newsletter™ Online
Authors:   American Academy of Pediatrics
Published: April 2022

Accessing the newsletter online
The Value of Using the Medicare Resource-Based Relative Value Scale in Your Practice
Authors:   American Academy of Pediatrics
Published: April 2022

How to calculate your practice conversion factor when using RBRVS
Can You Code This Hospital Stay?
Authors:   American Academy of Pediatrics
Published: April 2022

Tips from the AAP Section on Hospital Medicine Subcommittee on Billing & Coding
New ICD-9-CM Codes for 2009
Authors:   American Academy of Pediatrics
Published: April 2022

A comprehensive list of new diagnosis codes that apply to primary and subspecialty pediatrics, effective for reporting services performed on or after October 1, 2008
Practices Can Benefit From Certified Professional Coders' Knowledge
Authors:   American Academy of Pediatrics
Published: April 2022

Training, standards, and development certified by the American Academy of Professional Coders
American Medical Association Clarifies Reporting Requirements for Neonatal and Pediatric Critical and Intensive Care
Authors:   American Academy of Pediatrics
Published: April 2022

Clarification from AMA on neonatal and pediatric critical and intensive care supervision requirements
Coding for Pediatrics 2009, 14th Edition, Clarification
Authors:   American Academy of Pediatrics
Published: April 2022

Correction to an example in Coding for Pediatrics 2009 regarding a modifier used for a significant, separately identifiable service provided in the same visit as the intended service
Point to Ponder
Authors:   American Academy of Pediatrics
Published: April 2022

When 99401-99412 counseling risk factor reduction and behavior change intervention codes can be reported in conjunction with E/M services
Keep Up With the Joneses
Authors:   American Academy of Pediatrics
Published: April 2022

The importance of referencing the most current articles due to the frequency of code changes
Denial Den (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Denials based on payers not recognizing modifiers and other codes
Reporting Incident-to Services
Authors:   American Academy of Pediatrics
Published: April 2022

Outline of the Medicare incident-to guidelines with examples of how to report and document procedures and services, including split or shared services, diagnostic tests, and services commonly or never incident to
Perplexing: Reporting Pelvic Examinations and Papanicolaou Tests
Authors:   American Academy of Pediatrics
Published: April 2022

Allaying confusion on reporting services related to Pap smear testing and interpretation
Modifier Essentials
Authors:   American Academy of Pediatrics
Published: April 2022

Using modifiers 51 and 59 for procedures
New Category II Codes (Pay-for-Performance Measures) Applicable to Pediatrics
Authors:   American Academy of Pediatrics
Published: April 2022

Using Category II codes to monitor performance, patient compliance, and outcomes for common conditions
You Code It! (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Otitis media using new codes and referral and counseling for tympanostomy tube insertion
Do You Understand the Official ICD-9-CM Conventions?
Authors:   American Academy of Pediatrics
Published: April 2022

Avoiding the common mistake of coding from the index and not recognizing many of the symbols, abbreviations, notes, and coding guidelines that are critical in the selection of many codes
Denials to Dollars: Coverage for Telephone Care Services 1 Year Later
Authors:   American Academy of Pediatrics
Published: April 2022

Recognition of coverage for telephone care services
Physician Standby Services (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Physicians on standby and proper use of code 99360
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Chronic cough based on school nurse request, separation of post-circumcision adhesions, and travel consultation
Official ICD-9-CM Conventions: More Basics (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

How to interpret and use ICD-9-CM instructional notes
The Essence of Time: Prolonged Physician Services
Authors:   American Academy of Pediatrics
Published: April 2022

Guidelines and reporting requirements for prolonged physician care 99354 - 99359
Denials to Dollars
Authors:   American Academy of Pediatrics
Published: April 2022

AAP work on payment for 96110 developmental testing
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

ADHD followup, inpatient hospital consultation, fever secondary to a vaccine, unknown immunization status, and buddy-taping
ICD-9-CM and More CPT Errata (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Errata from the AMA
You Code It! (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Coding tips and teaching points for coding time spent in encounters, counseling, examination, review, and treatment
An Immunization Wellness Checkup
Authors:   American Academy of Pediatrics
Published: April 2022

AAP resources for coding, billing, and payment of immunization services
Ten Practice Pearls for Coding Immunization Services
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting immunization services
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Coding holiday hours, transcutaneous bilirubin, diapers, cosigning history notes, new patient visits, and review of ROS and PFSH
Standing By: Are You Reporting Your Time?
Authors:   American Academy of Pediatrics
Published: April 2022

When to report standby services
Point to Ponder
Authors:   American Academy of Pediatrics
Published: April 2022

Fourth- and fifth-digit coding for high specificity
Coding the Correct Level of Evaluation and Management Service
Authors:   American Academy of Pediatrics
Published: April 2022

Key components of E/M service performance and documentation
Step 2: Determine the Level of History Obtained and Documented
Authors:   American Academy of Pediatrics
Published: April 2022

Elements for the History level
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Vanderbilt testing for ADHD
Step 4: Determine the Level of Evaluation and Management Service
Authors:   American Academy of Pediatrics
Published: April 2022

E/M service level; 99211 - 99215
Are You Missing an Opportunity? Capture Your Care Plan Oversight Services!
Authors:   American Academy of Pediatrics
Published: April 2022

Capturing non-face-to-face physician services to coordinate care of a child with a chronic illness or special health care needs
Connect, Question, Convey, Participate…Communicate!
Authors:   American Academy of Pediatrics
Published: April 2022

Open communication between physicians and administrative staff to document, code and bill correctly
What Is the RUC?
Authors:   American Academy of Pediatrics
Published: April 2022

Survey process to recommend updates and changes to Medicare RBRVS
You Code It! Test Your Skill Using the 2010 ICD-9-CM Codes
Authors:   American Academy of Pediatrics
Published: April 2022

Test your skill with 2010 codes
Category II Codes: 2 New Performance Measures Applicable to Pediatrics
Authors:   American Academy of Pediatrics
Published: April 2022

Pay-for-performance Category II codes to measure and monitor Pediatric End-Stage Renal Disease and HIV/AIDS
Denials to Dollars
Authors:   American Academy of Pediatrics
Published: April 2022

Negotiating coverage and payment for venipunctures, capillary sticks, and specimen transfer to a laboratory
Reporting a Pelvic Examination With or Without Obtaining a Papanicolaou Test
Authors:   American Academy of Pediatrics
Published: April 2022

Table of CPT codes and guidelines for pelvic examinations under different types of visits
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting impacted cerument and removal of a foreign body in ear
New and Revised Pathology and Laboratory Codes in CPT 2010
Authors:   American Academy of Pediatrics
Published: April 2022

Codes 83986 and 83987 for exhaled breath condensate, and 86592 for syphilis testing
New Healthcare Common Procedure Coding System Code Effective for Services Performed On and After January 1, 2010
Authors:   American Academy of Pediatrics
Published: April 2022

Codes S3870 for comparative genomic hybridization (CGH) microarray testing for developmental delay
Follow-up or Aftercare? (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

ICD-9-CM guidelines for reporting follow-up and aftercare
2010 Medicare Resource-Based Relative Value Scale: Good and Bad News
Authors:   American Academy of Pediatrics
Published: April 2022

Newly accepted work RVUs for H1N1, practice expense transition over 4 years, and new codes for infant pulmonary function testing; elimination of office outpatient/inpatient consultation codes, echocardiography codes, moderate sedation
Denials to Dollars
Authors:   American Academy of Pediatrics
Published: April 2022

AAP appeal to major health plans to continue to provide benefits coverage and separate payment for consultations
Coding for Children With Special Health Care Needs Part 2
Authors:   American Academy of Pediatrics
Published: April 2022

Codes to report for patient self-management and physician educational services provided in a group setting
Observation or Inpatient Same-Day Admission and Discharge Services
Authors:   American Academy of Pediatrics
Published: April 2022

Clarifications on appropriate reporting of codes 99234-99236 for same-day observation and inpatient admisssion and discharge services
Pediatric Critical Care Transport Services
Authors:   American Academy of Pediatrics
Published: April 2022

Codes 99466 and 99467 for critical care transport services for a patient 24 months or younger
ICD-9-CM Coding Conundrums
Authors:   American Academy of Pediatrics
Published: April 2022

Still murmur omit code, acute bronchospasm versus acute asthma exaceration, fevers, observation and evaluation, and abuse versus suspected abuse
You Code It!
Authors:   American Academy of Pediatrics
Published: April 2022

Shortness of breath and wehezing and nebulizer treatment
Reporting Consultations Using Medicare Requirements
Authors:   American Academy of Pediatrics
Published: April 2022

Updated CMS requirements for consultation services 99241-99245 and 99251-99255
It's an Emergency!
Authors:   American Academy of Pediatrics
Published: April 2022

ED visit codes 99281-99285 for unscheduled episodic services provided in an organized 24-hour hospital-based facility on an immediate basis
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Newborn visit in physician’s office instead of hospital, classroom observation, counseling for unimmunized infant, and pregnant patient
Remote Critical Care Services
Authors:   American Academy of Pediatrics
Published: April 2022

Patient management by a physician at a distant site at the request of the on-site pediatrician
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Sensory integration disorder, referral to a child psychologist, and Gardasil for males
Launching Your Career in Pediatrics
Authors:   American Academy of Pediatrics
Published: April 2022

Discussion of scheduling methodologies to build a practice
Launching Your Career in Pediatrics
Authors:   American Academy of Pediatrics
Published: April 2022

Basic techniques to schedule for maximum efficiency based on seasonal variation, provider work styles, monitoring booking, authority to control provider schedules, data systems, and job streams
Coding for Seasonal Influenza Vaccines
Authors:   American Academy of Pediatrics
Published: April 2022

Codes for 2010-2011 seasonal and H1N1 influenza vaccines 90655 90656 90657 90658 and 90660
Reporting Injuries and Poisoning
Authors:   American Academy of Pediatrics
Published: April 2022

Using E codes E800-E999 for external causes of injuries, poisonings, and adverse effects
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Medicare global period for 17110 after wart removal, nurse performing history/physical exam and strep test and physician reviewning chart and writing prescription, and administration of ceftriaxone sodium (Rocephin)
Understanding Surgical Package Definitions (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Properly reporting surgical procedures
Coding for Vaccines and Immunization Administration in 2011: Major and Welcome Changes to the CPT 2011 Immunization Administration Codes
Authors:   American Academy of Pediatrics
Published: April 2022

New pediatric-specific immunization administration codes 90460 and 90461 replacing 90465-90468 effective January 1, 2011
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Referral for birth control
Clarification From the AMA—Again! - Observation or Inpatient Same-Day Admission and Discharge Services
Authors:   American Academy of Pediatrics
Published: April 2022

New guidelines for 99234-99236 and 99463 from AMA
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Prescription refills, auto-citation by EHR, and time as the controlling factor for E/M code selection
Be Watchful of Patient Enrollment Contract Provisions
Authors:   American Academy of Pediatrics
Published: April 2022

Limiting plan members if the plan has significant problems
2011 Medicare Resource-Based Relative Value Scale: A Primer
Authors:   American Academy of Pediatrics
Published: April 2022

Calculating medicare payments, Medicare CF with and without geographic adjustment, and Payer or Practice CF
New Pediatric Category II Codes: Pay-for-Performance Measures
Authors:   American Academy of Pediatrics
Published: April 2022

New Category II performance measures for epilepsy and major depressive disorder for reporting monitoring performance, patient compliance, and outcomes for incentive payments
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Cryotherapy of warts and a patient with otitis media and exposure to TB
Are You Getting New Denials From Medicaid?
Authors:   American Academy of Pediatrics
Published: April 2022

Understanding CMS NCCI edits that are mandated for all state Medicaid programs
Coding Quandary: Reporting Medications
Authors:   American Academy of Pediatrics
Published: April 2022

HCPCS codes J0100-J9999 for medications administered in an outpatient setting.
ICD-9-CM Coding Guidelines for Reporting Child Abuse (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

E codes for child abuse reported as secondary to problem codes and priority to all other E codes.
One Patient, 2 Physicians
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting concurrent care services based on the respective level of care performed by 2 or more physicians for the same patient
After-hours Services: One of the Top 10 Underused Codes
Authors:   American Academy of Pediatrics
Published: April 2022

Reporting codes 99050-99060 for physicians seeing patients on an emergent basis and seeing patients in the emergency department during office hours
Erratum: February 2010 “Q & A”
Authors:   American Academy of Pediatrics
Published: April 2022

Q&A includes incorrect codes for international travel
Q&A
Authors:   American Academy of Pediatrics
Published: April 2022

Finger stick glucose testing and prescribing OTC drugs or supplies
AAP Successfully Advocates for Changes to the Medicare Enrollment Rule
Authors:   American Academy of Pediatrics
Published: April 2022

Pediatricians exempted from the Medicare rule deactivating physicians who don’t bill Medicare for 12 consecutive months
Point to Ponder: Counting Medical Examination Elements
Authors:   American Academy of Pediatrics
Published: April 2022

Counting elements such as areas of examination not specifically cited in guidelines for examination
National Correct Coding Initiative Update
Authors:   American Academy of Pediatrics
Published: April 2022

NCCI response to AAP requests for edits to immunization administration and pediatric critical care transport codes
Coding Hospital Evaluation and Management Services for the Noncritical Patient
Authors:   American Academy of Pediatrics
Published: April 2022

When to report hospital observation services, hospital inpatient services, and observation or inpatient care same-day admission and discharge services 99217--99239
Q&A (Online Exclusive)
Authors:   American Academy of Pediatrics
Published: April 2022

Modifier AI, blanket fuzz removal, and croup and stridor
Point to Ponder: Reporting Sports Physicals
Authors:   American Academy of Pediatrics
Published: April 2022

Codes 99381-99397 with V70.3, 99211-99215, and 99241-99245 and billing parents or payers for services
Erratum: “National Correct Coding Initiative Update”
Authors:   American Academy of Pediatrics
Published: April 2022

Crosswalk of the former 99211-90465 code pair to the new code 99211-90460 code pair in Version 17.1