bluuebunny/crossref_metadata_2025 huggingface dataset:
Gastroretentive floating microspheres for the management hypertension based on drug combination of amlodipine /losartan
Authors: Rubab Ali  , Muhammad Naeem Aamir  , Nayab Khalid  , Muhammad Bilal
Published: August 2022

Background: Hypertension is one of the serious global health issues that affect millions of people and leads to cardiovascular damage if remain untreated. Various antihypertensive drugs have been developed but it is difficult to achieve better control of blood pressure by using mono-therapy so in this research work, combination therapy having sustained effect for the treatment of hypertension was developed. Method: Gastroretentive floating microspheres of amlodipine besylate and losartan potassium were formulated for the purpose of increasing the time of retention of drugs in the upper gastrointestinal tract and ultimately extend drug release. Eudragit RS100 was used as release controlling agent. The method adopted to prepare microspheres was solvent extraction. Formulated microspheres after that tested for assessing flow properties, buoyancy (%), percentage yield, drug release, surface morphology, by FTIR drug and polymer compatibility, size analysis and entrapment efficiency. Release kinetics on cumulative release data were applied. Results: It was observed from the findings that all the formulation remained buoyant in 1.2 pH buffer up to 12 hrs. It was also found that release of drug from formulation was prolonged which indicates sustained effect of dosage form. All the other results were satisfactory and it was also found that entrapment efficiency of formulation increased when concentration of polymer increased. On the basis of results, formulation 1 with 1:1 drug polymer ratio was selected as optimum formulation. Conclusion: It was concluded from the study that gastroretentive floating microspheres could be a one of best approach to extend the release of drug delivery system.
Aplicabilidade da ferramenta CURVA ABC como instrumento de gestão de estoque de uma empresa no ramo óptico no município de Capanema (PA).
Authors: Castro Débora Cardoso , Santana Sanderson de Andrade , Ferreira Mariângela do Nascimento , Lima Felipe Cunha , Carvalho Salma Sáraty de
Published: August 2022

Tem por finalidade analisar o atual modelo de gestão de estoque de umaempresa do ramo óptico e aplicar o método da curva ABC. Tem sua natureza aplicada e abordagem qualitativa para fazer a análise da gestão atual de estoque e quantitativa para a classificação da curva ABC. Os dados foram coletados através de uma entrevistasemiestruturadae pelas informações fornecidas pelo software da empresa, juntamente com o gerente e o proprietário, para a análise dos dados foi utilizada como base pesquisas bibliográficas. O resultado mostrou queao utilizar a ferramenta da Curva ABC, foi detectado o alto risco na gestão do estoque da empresa estudada, já que a estocagem das mercadorias ocorre em grande quantidade para aquelas com maior investimento. Contudo, faz-se necessário a aplicação de outros métodos de gestão de estoque que indiquem sobre o faturamento do período.
The Influence of Preschool Teachers’ Adaptability on Burnout Through Digital Literacy and Teaching Efficacy During the Covid-19 Pandemic: The Role of the On-line Teaching Experience
Authors: Kim Jaehee , Kang Yeonwha , Kim Hyoun K.
Published: August 2022

Objectives: This study examines the extent to which preschool teachers’ adaptability influences their burnout, focusing on the double mediating effects of digital literacy and teaching efficacy during the COVID-19 pandemic, and whether such effects are influenced by online teaching experiences. It aims to highlight the importance of teachers’ adaptability and digital literacy as protective factors in preventing burnout in situations of crisis or future virtual education environments.Methods: A total of 222 preschool teachers participated in the study and completed online questionnaires on their adaptability, digital literacy, teaching efficacy, burnout, and online teaching experiences during the COVID-19 pandemic. The data were analyzed using SEM and multigroup SEM in Mplus 8.2.Results: Overall, teachers’ adaptability was directly associated with their digital literacy, teaching efficacy, and burnout, and their teaching efficacy was directly associated with their burnout. Further, teachers’ digital literacy was directly associated with teaching efficacy and burnout, especially among teachers who had online teaching experiences during the COVID-19 pandemic. Moreover, teachers’ adaptability influenced burnout through their teaching efficacy, regardless of their online teaching experience. Additionally, the double mediating effects of digital literacy and teaching efficacy on the association between teachers’ adaptability and burnout were significant regardless of their online teaching experience.Conclusion: The results suggest that the efforts to facilitate teachers’ adaptability and digital literacy can be promising targets in their education to promote adaptive readiness for the new digital education model and to prepare for the the future unexpected crises, such as COVID-19.
The Mediating Role of Self-Differentiation and Parental Reflection in the Relationship Between Mother’s Own Childhood Overprotection Experience and Her Parenting Behavior
Authors: Kang Seo Ro , Oh Ji Hyun
Published: August 2022

Objectives: This study aims to determine how mothers’ parenting experiences affect their attitudes toward raising children. Specifically, it examines how the experience of being raised by overprotective parents affects a mother’s parenting behavior and analyzes the structural relationship and impact of self-differentiation and parental reflection variables on the relationship between the two variables.Methods: The study participants were mothers of infants found through children's institutions located in Gwangju and Jeollanam-do. The institutions had been selected randomly and consent was obtained from all participants. A total of 374 questionnaires were analyzed using SPSS 20.0 and SPSS PROCESS macro.Results: First, it was confirmed that self-differentiation completely mediated the relationship between mothers’ childhood overprotection experience and mothers’ negative parenting behavior through self-differentiation. Second, it was confirmed that parental reflection regulates the relationship between mothers’ childhood overprotection experience and self-differentiation. Third, the statistical significance of the controlled mediating effect of parental reflection was confirmed in the path in which the mother's childhood overprotection affected parenting behavior through self-differentiation. This suggests that, even if the mother was overprotected as a child and has a low level of self-differentiation, enhancing parental reflection can reduce negative parenting behaior.Conclusion: This study is meaningful in that it discovered the possibility of modifying the process of negative parenting behavior between generations through the parental reflection function. In addition, the fundamental limitations of the previous parental education were revised and suggestions were made for the development of parental education programs that involve the parental reflection functions.
The Effects of COVID-19-Related Stress on Depression in Working Mothers with School-Aged Children: The Moderated Mediation Effect of Parenting Efficacy and Cognitive Flexibility
Authors: Kim Ho Jung , Jang Hye In , Lee Dongmee , Park Ju Hee
Published: August 2022

Objectives: This study aimed to analyze the effects of COVID-19-related stress, parental efficacy, and cognitive flexibility on depression of mothers with school-aged children and to examine a moderated mediation model.Methods: Data on cognitive flexibility, parental efficacy, COVID-19-related stress, and depression were collected from 441 working mothers who had at least one school-aged child using the Cognitive Flexibility Inventory (CFI) and Parenting Sense of Competence (PSOC), COVID Stress/Disruption, and Center for Epidemiologic Studies Depression (CES-D) scales. Data were then analyzed using SPSS 26.0, and PROCESS macro version 4.0.Results: The findings revealed that COVID-19-related stress had a significant positive influence on depression in working mothers, which was mediated by parental efficacy. A moderated mediation analysis further indicated that this indirect effect varied depending upon the mothers’ sense of control a sub-factor of cognitive flexibility. Therefore, when mothers perceived they were unlikely to exercise any control over changes caused by the COVID-19 pandemic, their parental efficacy exerted a greater mediating effect.Conclusion: Results suggest that interventions reducing COVID-19-related stress and increasing parental efficacy could alleviate depression among working mothers with school-aged children. Furthermore, cognitive interventions could be effective in helping those working mothers experiencing a low level of parenting efficacy due to COVID-19-related stress to perceive the demanding situation as within their control.
Teilnahme an der Tarifentwicklung nach Betriebsübergang
Authors: Sandforth Luisa Manon
Published: August 2022

This thesis examines possible ways to ensure that future updates of collective bargaining agreements will apply after a transfer of undertakings. Such measures are often desired by employees, usually represented by works councils or trade unions, since the German law only provides for the application of collectively agreed rules that are in force at the date of the transfer. The author discusses the validity and the temporal scope of various security agreements. In addition, the author examines which parties - transferor, transferee, works council, trade union or employee – can enter into such agreement, and, in particular, whether agreements can also be enforced by a trade union through strike action.
Rechtsnormen und Legitimität in der Friedensmediation
Authors: Würkert Felix
Published: August 2022

Peace mediation does not take place in a legal void, but often in a norm-critical or even norm-averse environment. This book contrasts this with the fact that legal conformity contributes to successful and legitimate mediation and that mediation also needs this legitimacy because it itself exerts a lasting influence. However, this need for legitimacy cannot be satisfied without taking legal norms into account. This circumstance is explained, as are the legitimacy issues to which legal norms themselves are exposed and which thus also limit the legitimatory potential for peace mediation.
Dingliche Sicherungsrechte in grenzüberschreitenden Restrukturierungen
Authors: Kockrow Jan Christian
Published: August 2022

The thesis deals with the supranational protection of rights in rem in assets which are situated within the territory of another Member State at the time of the opening of cross-border proceedings, particular of im-pairments of the right in rem in the context of the German insolvency plan. The norm of Art. 8 (1) EIR is intended to resolve the tension of rights in rem between a universal procedure and the 26 different property and insolvency laws of the Member States. This is significant, since the integrity of the property law system is of extraordinary importance for credit protection law. Nevertheless, this arrangement must not be at the expense of the effectiveness and economic efficiency of the procedure.
The psychological effects of imprisonment: The role of cognitive, psychopathic and affective traits
Authors: Lanciano Tiziana , de Leonardis Lidia , Curci Antonietta
Published: August 2022

The present cross-sectional correlational study aimed to investigate a set of cognitive, affective, and personality traits impacting the psychological effects of imprisonment. Ninety-three male inmates filled out a battery including measures of intelligence, working memory, psychopathy, aggressiveness, anxious trait, emotionality, rumination styles, and empathy proneness. Inmates' psychological outcomes were conceptualized in terms of mood, anxiety, depression, and general health. Results showed that inmates with high cognitive abilities, psychopathic impulsivity, proactive aggression, personal distress and fantasy, anxious and negative emotionality are mainly prone to ill-being psychological outcomes. Contrariwise, the fearless dominance trait, positive emotionality and empathic concern ability seem to expose inmates to positive psychological outcomes. Reactive aggression and perspective taking seem to impact both positive and negative moods. Ruminative style was unrelated to psychological outcomes. These preliminary results provide an insight into which factors intervention programs should be based upon in order to enhance well-being and reduce distress among inmates.
The relation between empathy and aggression: The role of attachment style
Authors: Lo Cricchio Maria Grazia , Musso Pasquale , Lo Coco Alida , Cassibba Rosalinda , Liga Francesca
Published: August 2022

This study aimed to examine the explaining and moderating role of attachment style profiles on the association between empathy and aggression. Participants were 548 Italian adults (M = 47.62 years, SD = 6.14) who completed a survey measuring attachment, empathy, and aggression. Using cluster analytic methods, initial results indicated two attachment style profiles to be considered (secure vs. insecure). However, we also extracted a more theoretically guided four-cluster solution including preoccupied, secure, fearful, and dismissing profiles. Moreover, structural equation modelling showed that higher levels of empathy linked to lower levels of aggression. Nonetheless, when introducing in the model the dichotomous or the multi-categorical attachment style profile variable as predictive of both empathy and aggression, their association became not significant, while secure attachment profile significantly presented higher levels of empathy and lower levels of aggression compared to the other profiles. Furthermore, attachment style profile moderated the link between empathy and aggression. Specifically, in the secure group empathy and aggression were negatively related, but no significant association was evidenced in the other groups. Findings are discussed in the light of the literature.
Refugee mothers mental health and social support needs: A systematic review of interventions for refugee mothers
Authors: Abi Zeid Daou Kim Roger
Published: August 2022

Refugee mothers endure and are at risk for depression, post-traumatic stress, suicidality, and anxiety. There is a gap in the literature regarding interventions for refugee mothers’ mental health and well-being. Interventions involving refugee mothers rarely provide adequate support for refugee mothers’ specific mental health needs and challenges. This paper presents empirical evidence to contextualize the risks refugee mothers face, such as gender-based violence, mental health challenges, and language barriers. Then, the paper provides a critical systematic review of interventions conducted with refugee mothers. The critical systematic review suggests that creating and providing a safe space, being a linguistic liaison, community-building, and advocating for refugee mothers’ needs are emergent protective factors for refugee mothers. Finally, based on the review, recommendations for future interventions followed.
Impact of Resilience on Psychological Well-Being
Authors: Niyazova Adina , Madaliyeva Zabira
Published: August 2022

Background: The issue of the individual's psychological well-being is one of the most interesting and relevant in psychology. Its study has implications not only for theoretical but also for many of the present practical challenges. This study explores predictors of psychological well-being, one of which is resilience.

Objective: The purpose of the study is to analyse psychological well-being predictors and prove that resilience is one of its important predictors.

Methods: To achieve the aim, a theoretical grounding of the key concepts was made, and an empirical study was carried out. The following techniques were used: the Ryff Scales of Psychological Well-Being, the Freiburg Personality Inventory and the Maddi's Hardiness Survey. Furthermore, at the empirical level, the characteristics of resilience among different age groups were recorded.

Results: The study presents the results of a survey involving 150 people of different ages related to the profession of consulting psychologists. Furthermore, the study identified the following predictors of psychological well-being: resilience, femininity/masculinity, positive attitudes, emotional lability, irritability, and aggression.

Conclusions: Based on the study of psychological and pedagogical literature and the study findings, it has been concluded that resilience should be considered a mechanism for achieving psychological well-being. The theoretical analysis described the concepts of "psychological well-being" and "resilience", providing their characteristics and factors.
The Impact of Emotional Intelligence on the Academic Performance of Students with Intellectual Disabilities in Inclusive Education
Authors: Vovchenko Olha , Leonova Inna , Soroka Iryna , Klymenko Iryna , Tsekhmister Yaroslav
Published: August 2022

Background: The development of inclusive education involves the increasing participation of children and adolescents with intellectual disabilities in the general education process, which can be accompanied by several stressful and psychotraumatic situations that negatively affect the academic success of such adolescents.

Objective: This study aimed to empirically test the probability that the emotional intelligence level of adolescents with intellectual disabilities impacts their academic performance.

Methods: The study was conducted as a socio-psychological experiment involving experimental and control groups through pre-test and post-test measurements of the emotional intelligence level of adolescents with intellectual disabilities and their academic performance. The study involved students at comprehensive secondary schools aged 12-14 who studied in inclusive classes.

Results: The Emotional Intelligence Development Programme also aimed to further the inclusion of adolescents in their school lives. The Programme involved a series of classes with a predominance of visual material adapted to the needs of adolescents with intellectual disabilities. The research was motivated by the improvement of inclusive education in Ukraine, which is at the stage of its formation. The Programme is based on applied developments of practical psychologists with the author's extensions. The study was carried out through the EmIn Test adapted by Lyusin to diagnose the level of emotional intelligence. Observations, one-way analysis of variance (ANOVA), Pearson correlation coefficient, and comparison of means through student's t-test were used to analyze the data obtained. The Programme resulted in increased parameters for the emotional intelligence level in the experimental group compared to the control group and improved academic performance in Mathematics and Biology. The results obtained empirically confirmed the positive impact of emotional intelligence on the academic performance of children with intellectual disabilities.

Conclusion: The primary value of the study was the integration of the author's approaches in the development of emotional intelligence of adolescents with intellectual disabilities. The practical result of the research is the methodological systematization of the experiment results with the aim of further implementation in the general educational process. Further research suggests monitoring the long-term effects of therapeutic intervention programs in working with adolescents with intellectual disabilities.
Effectiveness of prophylactic calcium and vitamin D supplementation for preventing post-thyroidectomy hypocalcemia: a meta-analysis
Authors: Moon Hyeyeon , Seok Ju Won , Kim Keunyoung , Kim Hye Young , Park Mi Kyoung , Kim In Joo , Pak Kyoungjune , Suh Sunghwan
Published: August 2022

Background: Postsurgical hypocalcemia is the most common and troublesome consequence of thyroidectomy. We investigated the potential role of routine calcium or vitamin D supplementation in preventing postsurgical hypocalcemia. Methods: We searched MEDLINE and Embase for English-language publications using the keywords “calcium,” “vitamin D,” and “thyroid cancer.” The primary outcome was any postoperative hypocalcemia, and the secondary outcome was symptomatic hypocalcemia. Results: Four studies that included 381 patients were eligible for this meta-analysis. A random-effects model showed no significant difference in the occurrence of hypocalcemia between calcium/vitamin D treatment and placebo/no treatment. However, the occurrence of symptomatic hypocalcemia was lower in patients with calcium/vitamin D treatment. In the combined results, preoperative calcium and vitamin D supplementation were associated with a reduced incidence of symptomatic hypocalcemia. Conclusions: Our findings support the use of preoperative calcium and vitamin D supplementation in conjunction with routine postsurgical supplementation for patients after total thyroidectomy.
Medicine and the Law
Authors: Thaldar D W
Published: August 2022

South African fertility clinics often include a provision in their consent forms that deals with the disposition of reproductive material (gametes and embryos) after a fertility patient’s death. This practice is problematic as such a provision is not legally valid. If the clinic acts in pursuance of such a provision upon a fertility patient’s death, the fertility clinic may be committing a civil wrong and a crime. Accordingly, consent forms should not include any provision that deals with the disposition of reproductive material after a fertility patient’s death. Instead, to address the practical concern of keeping reproductive material cryopreserved without receiving payment, fertility clinics’ storage agreements should use non-payment by fertility patients (or their successors in title) as the trigger event for the disposition of reproductive material. The importance of dealing with reproductive material in both its property rights dimension and its personality rights dimension is highlighted.
Improved Cosmic Ray Spectrum and Intensity in Middle Atmosphere (CORSIMA) Model Considering Six Characteristic Energy Intervals
Authors: Velinov Peter , Asenovski Simeon , Mateev Lachezar
Published: August 2022

The new model CORSIMA (COsmic Ray Spectrum and Intensity in Mid- dle Atmosphere) is presented in this study. Numerical determinations of the spectrum and intensity of Galactic Cosmic Rays (GCR) for the middle atmo- sphere and the lower altitudes of the ionosphere (30–80 km) are presented. These altitudes are above the Regener–Pfotzer maximum. The primary spec- tra of protons and helium (alpha particles) are used. According to the amount of particles, cosmic rays consist of 92% protons, 6% helium nuclei, 1% heavier elements, and 1% electrons (GINZBURG and SIROVATSKY [19]).

We also use the approximation of ionization losses (Bohr–Bethe–Bloch formula) in six characteristic energy intervals, including the charge decrease interval for electron capture. In this way, the accuracy of the obtained results is improved.

Analytical expressions for the contributions of the energy intervals are provided. An approximation of the ionization function on six energy intervals is used and the charge decrease interval for electron capture is studied. Numerical calculations are performed using computational algebra systems.

The development of this research is important for a better understanding of the processes and mechanisms of space weather. The GCR affect the ionization and electrical parameters in the atmosphere and also the chemical processes (ozone formation and depletion in the stratosphere) in it. These effects can be significantly enhanced during strong and moderately strong solar proton events and geomagnetic storms.
Dynamic Problem for a Viscoelastic Hollow Cylinder with Coaxial Elastic Inclusion
Authors: Pshenichnov Sergey , Ryazantseva Marina , Ivanov Radan , Datcheva Maria
Published: August 2022

A problem of non-stationary longitudinal wave propagation in the cross-section of an infinite hollow linear-viscoelastic cylinder with coaxial elastic inclusion is considered. On the contact surfaces between the layers, continuity of displacements and stresses is assumed. The solution of the problem is constructed using the integral Laplace transform in time with subsequent reversal. For the case when each of the relaxation kernels is a finite sum of exponentials, the original is presented as a series of residues. Thus, the process of constructing a non-stationary solution is reduced to the search for the roots of the characteristic transcendental equation. The derived solution allowed to investigate the transient wave propagation in a viscoelastic cylinder with coaxial elastic inclusion with specified initial data.
Relevance of CMV DNA Detection in Symptomatic Children up to 3 Months of Age
Authors: Stoykova Zhivka , Ivanova Liliya , Yordanova Diana , Cvetkova Snejinka , Kalchev Kalin
Published: August 2022

Cytomegalovirus (CMV) is the most frequent cause of congenital infection worldwide. The burden of disease related to congenital CMV (cCMV) is substantial, as it is the leading cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities in children. Despite its clinical significance, cCMV infection often goes undetected because the majority of infected infants are asymptomatic at birth and screening programmes have not been implemented in any country.

The aim of this study is to define the role of CMV in congenital and early postnatal morbidity in clinically relevant symptomatic children up to 3 months of age in Varna region, comparatively in ELISA (anti CMV IgM/IgG) and PCR.

We found CMV DNA in 12 out of 50 tested children (24%, 95% CI: 12.16–35.84%). The viral load ranged in 65–1 628 879 IU/ml, average viral load 144 707.2 IU/ml.

It is important to note that only half of the PCR positive children 6/12 (50%) had an anti CMV IgM positive result.

Our data demonstrate that serological tests defining active CMV infection with CMV IgM detection are not sufficiently indicative in all newborns, and it is therefore mandatory to conduct modern PCR for all relevant infants after birth.
Ventricular Tachycardia Electrical Storm
Authors: Kascak Jelena , Andjelic Sladjana , Teofilovski Gordana
Published: August 2022

The term “electrical storm” (ES) indicates a life-threatening clinical condition characterized by the recurrence of hemodynamically unstable ventricular tachycardia (VT) and/or ventricular fibrillation (VF). We are presenting a case of ES in hemodynamically unstable VT treated at pre-hospital and hospital level.

Seventy-one-year-old patient with a previous history of hypertension, insulin-dependent diabetes, congestive stroke and myocardial infarction, severe three-vessel coronary artery disease and myocardial revascularization, diabetic nephropathy, chronic kidney failure, and chronic ischemic cardiomyopathy, collapses at home. After examination and diagnostic procedures, the emergency medical physician (EMS) diagnoses hemodynamically unstable VT, which he treats with medication and gets the patient urgently transported to a hospital. In the next 24 h, during hospitalization, there are five more separate episodes of VT with pulse treated with DC shock and antiarrhythmics. On the twelfth day of hospitalization, an implantable cardioverter-defibrillator is implanted to prevent sudden cardiac death. On the seventeenth day, the patient is discharged from hospital in stable condition.

The question arises of further best pharmacological and non-pharmacological therapy of ES in hemodynamically unstable VT. It is necessary to educate EMS physicians in the practical application of synchronized cardioversion at the prehospital level.
Molecular Characterization of Service Tree (Sorbus domestica L.) Genotypes Selected from Tokat Province
Authors: Atasever Oznur , Erdem Sinem
Published: August 2022

This study was carried out to determine the genetic diversity of eleven service tree (Sorbus domestica L.) genotypes selected from Tokat province and taken under protection in the genetic resource plot. In the present study, ISSR-PCR studies were carried out on genotype DNAs obtained by Mini-CTAB method and the level of polymorphism between genotypes was determined us- ing seven UBC-ISSR primers. A total of 65 bands were obtained in service tree genotypes with seven primers and 56 of these bands were determined to be polymorphic. The number of bands obtained per primer varied between 5 and 12, the mean band number was 5.90, and the mean polymorphic band number was 5.09. The data obtained as a result of the evaluation of ISSR-PCR bands were analyzed in Popgene32 and MEGA5.0 computer package program, and a dendrogram was obtained according to the UPGMA method. In the dendro- gram obtained, it was determined that two groups were formed at the level of approximately 22% difference, and there was only one genotype in the small group while the other genotypes were in the large group.
Evaluation of the Physiological and Behavioural Relationships of Yearling Bucks by Generalized Procrustes Analysis
Authors: Karaca Serhat , Ser Gazel
Published: August 2022

The aim of this study is to evaluate the relationships between some sexual behaviours and physiological traits such as serum testosterone concentration, body weight loss and presence of horns of yearling bucks using Generalized Procrustes Analysis (GPA). In the study, 11 yearling bucks being sexually in- experienced were used. The sexual behaviours were determined with a total of four tests, which consisted of exposing the yearling bucks individually to three unrestrained estrous ewes for 15 min. In these tests, some behavioural characteristics such as number of ejaculations, flehmen response, number of mounts and serum testosterone concentration were determined. In the GPA analysis, the first two factors explained approximately 98% of the total variation between animals (Dimension 1 = 95.57%, Dimension 2 = 2.68%). It was determined that there was a positive and high correlation between tests and the number of mounts, which had a high correlation with the first dimension. Ejaculation frequency, flehmen response and testosterone levels decreased in line with in- creases in the number of mounts. As a result, it can be suggested that GPA can be effectively evaluated quantitative and qualitative behavioural characteristics without requiring any prior assumptions and reducing variability among animals.
Molecular Identification of Beauveria bassiana and Metarhizium anisopliae Isolates and Their Bio-control Potential against Acanthoscelides obtectus and Sitophilus Zeamais
Authors: Karabörklü Salih
Published: August 2022

Acanthoscelides obtectus and Sitophilus zeamais are among the most damaging stored-product insect pests. This study was carried out to identify Beauveria bassiana and Metarhizium anisopliae and to evaluate their insecticidal potential against A. obtectus and S. zeamais adults. Fungal isolates were characterized molecularly based on ITS1, 5.8S and ITS2 regions of rDNA. B. bassiana YK23 and YK26, and M. anisopliae YK41 and YK45 were sprayed onto adults of A. obtectus and S. zeamais at 1×105, 1×106 and 1×107 conidia mL−1 doses. At the end of the 10th day of application, the numbers of dead adults were counted. Mortality rates (%) and lethal times (LT50 and LT90) were calculated for each isolate. Fungal isolates displayed promising insecticidal activity against A. obtectus and S. zeamais. B. bassiana and M. anisopliae caused 100% mortality against A. obtectus, even at the lowest dose. However, B. bassiana and M. anisopliae caused 100% mortality on S. zeamais at higher doses. Depending on the increasing doses, significant decreases were observed at the lethal times. Median lethal time (LT50) decreased up to 64.24 h (2.67 days) and 53.69 h (2.24 days) in A. obtectus exposed to B. bassiana and M. anisopliae, respectively. LT50 decreased to 61.04 h (2.54 days) and 53.89 h (2.25 days) in S. zeamais exposed to the same fungi. B. bassiana and M. anisopliae can be taken into account in the control of those pests.
Characterization of sequence determinants of enhancer function using natural genetic variation
Authors: Yang Marty G , Ling Emi , Cowley Christopher J , Greenberg Michael E , Vierbuchen Thomas
Published: August 2022

Sequence variation in enhancers that control cell-type-specific gene transcription contributes significantly to phenotypic variation within human populations. However, it remains difficult to predict precisely the effect of any given sequence variant on enhancer function due to the complexity of DNA sequence motifs that determine transcription factor (TF) binding to enhancers in their native genomic context. Using F1-hybrid cells derived from crosses between distantly related inbred strains of mice, we identified thousands of enhancers with allele-specific TF binding and/or activity. We find that genetic variants located within the central region of enhancers are most likely to alter TF binding and enhancer activity. We observe that the AP-1 family of TFs (Fos/Jun) are frequently required for binding of TEAD TFs and for enhancer function. However, many sequence variants outside of core motifs for AP-1 and TEAD also impact enhancer function, including sequences flanking core TF motifs and AP-1 half sites. Taken together, these data represent one of the most comprehensive assessments of allele-specific TF binding and enhancer function to date and reveal how sequence changes at enhancers alter their function across evolutionary timescales.
Industrial storage system continuous perforated uprights: a combined design proposal
Authors:   Department of Construction and Structures, Federal University of Bahia, Bahia (Brazil), Neiva Luiz , Braz Starlino Juliane Aparecida ,   Department of Civil Engineering, Federal University of Ouro Preto, Minas Gerais (Brazil), Elias Guilherme ,   Department of Civil Engineering, Federal University of Ouro Preto, Minas Gerais (Brazil), Cunha Sarmanho Arlene Maria ,   Department of Civil Engineering, Federal University of Ouro Preto, Minas Gerais (Brazil), Nicchio Alves Vinícius ,   Department of Civil Engineering, Federal University of Ouro Preto, Minas Gerais (Brazil)
Published: August 2022

Brazilian standards for design of cold-formed steel (ABNT NBR 14762:2010, 2010) and design of pallet racks (ABNT NBR 15524-2:2007, 2007) have different procedures to determine the strength of columns under axial compression, using different buckling curves. This paper aims to evaluate the efficiency of using cold-formed Brazilian standard buckling design curve instead of the formulations of the pallet-rack design standard to study the use viability of the equations in the calculation procedure for computing the uprights compressive strength. This strength was calculated in four ways: one using the original equations of pallet-rack Brazilian standard, and the other three using adaptations of the buckling curve from the cold-formed steel design standard. A theoretical and numerical procedure based on finite element analysis concerning local, global, and distortional buckling and imperfections was performed. Furthermore, experimental results were also consulted to determine the effective area of studied cross-sections considering the effects of local buckling and the presence of continuous perforations. The results show that the proposed modifications are consistently correlated to the results obtained using the original equations of ABNT NBR 15524, indicating the viability of using the buckling curve of ABNT NBR 14762.
Effect of aerogel/silica fume under curing methods on properties of cement-based mortars
Authors:   Istanbul University-Cerrahpasa, Department of Civil Engineering, Istanbul (Türkiye), Uatundag Ozlem , Celik Sola Ozlem ,   Istanbul University-Cerrahpasa, Department of Civil Engineering, Istanbul (Türkiye)
Published: August 2022

In this study, the mechanical, thermal and porosity properties of mortar samples containing aerogel and silica fume under different curing conditions were investigated. For this purpose, 0%, 0.25% and 0.50% by weight of silica aerogel as a cement additive and 10% silica fume as an industrial waste material were incorporated in the cement mixtures. The prepared mortar samples were exposed to curing process in water, the wetting-drying effect and MgSO4 effect for 16 weeks. The highest thermal conductivity reduction of 31.2% was obtained from the water curing sample with silica fume addition at an aerogel content of 0.25%. Maximum compressive and flexural strengths were determined respectively from samples with silica fume addition at an aerogel content 0.50% as 74.5 MPa and no aerogel content as 11.3 MPa by wetting-drying curing. However, the lowest thermal conductivity coefficient was measured as 1.458 W/mK from the sample at an 0.25% aerogel content containing silica fume which completed the curing process under the influence of MgSO4 with a highest compressive strength increase by 24.6%.
Effect of compression casting technique on the water absorption properties of concrete made using 100% recycled aggregates
Authors:   Department of Civil Engineering, University of Engineering and Technology Lahore, Lahore (Pakistan), Hameed Rashid , Un-Nisa Zaib ,   Department of Civil Engineering, University of Engineering and Technology Lahore, Lahore (Pakistan), Rizwan Riaz Muhammad ,   Department of Civil Engineering, University of Engineering and Technology Lahore, Lahore (Pakistan), Ali Gillani Syed Asad ,   Department of Civil Engineering, University of Engineering and Technology Lahore, Lahore (Pakistan)
Published: August 2022

Effect of compression casting technique on the water absorption characteristics of low grade 100% Recycled Aggregate Concrete (RAC) of target strength range 11 to 15 MPa to be used in the manufacturing of masonry units is investigated. Water absorption characteristics were determined by performing sorptivity test. Recycled aggregates were produced by crushing laboratory-tested concrete samples of strength ranging from 21 MPa to 28 MPa. Two different ratios of recycled coarse aggregate and recycled fine aggregates were investigated using two different cement contents. For comparison, natural aggregate concrete mixes were also tested. The study parameter included effect of aggregates type, casting pressure, casting technique and cement content on the water absorption properties of RAC. Further, depth of penetration of salt was observed using silver nitrate solution after 3-month immersion in 10% NaCl solution. The results of sorptivity test showed positive impact of compression casting technique on water absorption properties of low grade 100% RAC. Further, results showed that RAC mixes exhibited inferior water absorption properties compared to natural aggregates concrete mixes. Various equations were proposed to predict water absorption of 100% RAC under different conditions of casting pressure and cement content based on initial and secondary rate of water absorption.
Study of Nitric Oxide and Lipid Peroxidation in Preterm Labour: A Case-control Study
Authors: Chavan Monika Nandkumar , Ganu ayashree , Jadkar Sangita , Yadav Arvind , Nillawar Anup N
Published: August 2022

Introduction: Preterm Labour (PTL) is a major obstetric health problem. It contributes to 75% of neonatal mortality worldwide. According to a World Health Organisation (WHO) report, 15 million preterm birth occur every year. Nitric Oxide (NO), synthesised by three isoforms of NO Synthase (NOS) play physiological role in uterine muscle relaxation and prevention of preterm labour contractions. NO is also demonstrated to react with Reactive Oxygen Species (ROS). Aim: To assess the level of serum NO, Malondialdehyde (MDA) (end product of lipid peroxidation), total protein, albumin, calcium, and inorganic phosphorus in PTL) and also to compare these parameters with full-term labour. Materials and Methods: A case-control study was conducted in the Department of Biochemistry and Obstetrics and Gynaecology, Government Medical College, Miraj, Maharashtra, India, during the period of November 2014 to May 2015. Study included 60 women with age ranged between 21-31 years and gestational age between 28 to 37 weeks. Out of total 60 women, 30 were full-term labour, served as control and 30 women who had regular uterine contraction before 37 weeks were selected as cases. Estimation of NO (as nitrite) and MDA, Total Protein (TP), Albumin, Calcium and Inorganic Phosphorus was done. Data were analysed by applying a Student’s t-test and Pearson correlation test. Results: The mean maternal age was 26.53±3.42 years for cases and for control 27.63±2.51 years. The mean gestational age in cases was 31.1±2.795 weeks, whereas in controls was 37.26±0.520 weeks. A highly significant decrease in NO (7.1967±1.236 μmol/L and 15.900±3.897 µmol/L in PTL and control group), TP (4.996±0.509 g/dL and 6.906±0.480 g/ dL in PTL and control group), Albumin (3.460±0.440 g/dL and 4.406±0.390 g/dL in PTL and control group), calcium (8.240±0.431 mg/dL and 8.950±0.486 mg/dL in PTL and control group) and inorganic phosphorus (2.006±0.532 mg/dL and 3.786±0.537 mg/dL in PTL and control group) concentration was observed in PTL as compared to the controls. Lipid peroxidation (MDA) (10.590±0.8715 mg/dL and 5.6500±0.4725 mg/dL in PTL and control group) was found to be significantly increased in PTL as compared to controls. Conclusion: There was significant drop in the NO and increase in ROS reflected by increase in serum MDA levels in PTL group as compared to normal full-term labour. These parameters may have role in the diagnosis and prevention of PTL after appropriate larger cohort studies.
Consequences of the Australian 2019/20 wildfires for sites important for biodiversity and other world heritage values
Authors: Ward Michelle , Watson James E.M. , Greenville Aaron , Maurer Golo , Todd Stephanie , Geary William , Tulloch Ayesha
Published: August 2022

The 2019/20 wildfire season was devastating for Australia’s biodiversity and unprecedented in its extent and severity, yet the consequences for sites important for biodiversity and other world heritage values remain unknown. Here, we summarise the 2019/20 wildfire impacts on key sites set aside for, or identified as being important for, biodiversity, with specific reference to nationally designated protected areas, World Heritage Listings, and Key Biodiversity Areas (KBAs). We also explore patterns between burn extent or severity, and underlying landscape characteristics. Over seven months, approximately 10 million hectares (ha) of native vegetation burned. Of these burned landscapes, ~3.2 million ha (41%) were within the Australian protected area estate (n = 815 and impacted >0.1% of each protected area). Six Australian World Heritage Listings were impacted by the 2019/20 wildfires, with the largest impact being in the Greater Blue Mountains World Heritage Area (680,000 ha or 67% was affected by the fires). The 2019/20 fires impacted over 2 million ha across 69 KBAs. Of these, 18 KBAs had >15% of their area burned. Critically, for the management of intact and recovering forests, we show that the degree of forest integrity and ecosystem intactness affected fire severity: more degraded forests and ecosystems experienced higher severity burns in the protected area estate and KBAs. Recovery for many of these places will require targeted effort and resources to help reduce the likelihood of future megafires, as well as increased resilience in the face of other catastrophic environmental events.
Topological conjugacy of topological Markov shifts and Ruelle algebras
Authors:   Department of Mathematics, Joetsu University of Education, Joetsu, 943-8512, Japan, Matsumoto Kengo
Published: August 2022

We will characterize topological conjugation for two-sided topological Markov shifts (¯¯¯¯¯XA,¯¯¯σA) in terms of the associated asymptotic Ruelle C∗-algebra RA and its commutative C∗-subalgebra C(¯¯¯¯¯XA) and the canonical circle action. We will also show that the extended Ruelle algebra ˜RA, which is a unital and purely infinite version of RA, together with its commutative C∗-subalgebra C(¯¯¯¯¯XA) and the canonical torus action γA is a complete invariant for topological conjugacy of (¯¯¯¯¯XA,¯¯¯σA). The diagonal action of γA has a unique KMS-state on ˜RA, which is an extension of the Parry measure on ¯¯¯¯¯XA.
A program for finding all KMS states on the Toeplitz algebra of a higher-rank graph
Authors:   School of Mathematics and Statistics, Victoria University of Wellington, Wellington, 6140, New Zealand, Fletcher James , an Huef Astrid ,   School of Mathematics and Statistics, Victoria University of Wellington, Wellington, 6140, New Zealand, Raeburn Iain ,   School of Mathematics and Statistics, Victoria University of Wellington, Wellington, 6140, New Zealand
Published: August 2022

The Toeplitz algebra of a finite graph of rank k carries a natural action of the torus Tk, and composing with an embedding of R in Tk gives a dynamics on the Toeplitz algebra. In this paper we describe a program for determining the simplex of KMS states associated to this dynamics at all inverse temperatures. For inverse temperatures larger than a critical value, the KMS states are well-understood, and this analysis is the first step in our program. At the critical inverse temperature, much less is known, and the second step in our program is an analysis of the KMS states at the critical value. This is the main technical contribution of the present paper. The third step in our program shows that the problem of finding the KMS states at inverse temperatures less than the critical value is equivalent to our original problem for a smaller graph. We test our program on a wide range of examples, including a very general family of graphs with three strongly connected components.
Mixed products of Toeplitz and Hankel operators on the Fock space
Authors:   School of Mathematics and Statistics, Central South University, Hunan 410083, China, Ma Pan , Yan Fugang ,   College of Mathematics and Statistics, Chongqing University, Chongqing 401331, China, and Department of Mathematics and Statistics, SUNY, Albany, NY 12222, U.S.A., Zheng Dechao ,   Department of Mathematics, Vanderbilt University, Nashville, TN 37240, U.S.A. and Center of Mathematics, Chongqing University, Chongqing 401331, China, Zhu Kehe ,   Department of Mathematics and Statistics, SUNY, Albany, NY 12222, U.S.A. and Department of Mathematics, Shantou University, Shantou, Guangdong 515063, China
Published: August 2022

For entire functions f and g we determine exactly when the product H¯¯¯fT¯¯¯g of the Hankel operator H¯¯¯f and the Toeplitz operator T¯¯¯g is bounded on the Fock space F2α. This solves a natural companion to Sarason's Toeplitz product problem.
On norm-limits of algebraic quasidiagonal operators
Authors:   Department of Pure Mathematics, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada, Marcoux Laurent W.
Published: August 2022

It is still an open question to know whether or not every quasidiagonal operator can be expressed as a norm-limit of algebraic quasidiagonal operators. In this note, we provide an alternative characterization of those operators which may be expressed as such limits, in the hope that this may lead to a solution of this problem.
Curious properties of free hypergraph C∗-algebras
Authors:   Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany, Fritz Tobias
Published: August 2022

Given a finite hypergraph H, the \textit{free hypergraph C∗-algebra} C∗(H) is freely generated by a projection for each vertex subject to partition of unity relations specified by the hyperedges. We prove that the class of free hypergraph C∗-algebras coincides with the finite colimits of finite-dimensional commutative C∗-algebras, and with the C∗-algebras of synchronous nonlocal games. It is known that determining whether C∗(H)≠0 for given H is undecidable. We prove that it is also undecidable to determine whether C∗(H) is RFD, whether C∗(H) has only infinite-dimensional representations, and whether it has a tracial state. For each of these properties, there is H such that whether C∗(H) has this property is independent of ZFC (if ZFC is consistent).