bluuebunny/crossref_metadata_2025 huggingface dataset:
Pula obserwatorów powrotów przymusowych Frontexu: geneza powstania, prawne i organizacyjne ramy funkcjonowania i rozwój działalności
Authors: Żłobecki Michał Jan
Published: September 2021

Przyjęty w 2015 r. Europejski Program w Zakresie Migracji ujawnił potrzebę dokonania zmiany podstawy prawnej Frontexu, aby zwiększyć jego rolę w zakresie powrotów migrantów o nieuregulowanym statusie, przy jednoczesnym poszanowaniu ich podstawowych praw. Zgodnie ze znowelizowanymi przepisami wszystkie deportacje koordynowane lub organizowane przez Frontex mają być monitorowane. Jednocześnie utworzona została wewnętrzna pula obserwatorów ds. powrotów przymusowych, która pełnić miała rolę subsydiarną w stosunku do krajowych mechanizmów monitorowania deportacji. Z uwagi jednak na niską efektywność systemów krajowych, liczba przymusowych powrotów obserwowanych przez członków puli Frontexu stale wzrasta. Autor omawia genezę utworzenia puli obserwatorów, prawne i organizacyjne ramy jej funkcjonowania i rozwój działalności na przestrzeni ostatnich lat.

Frontex Pool of Forced-Return Monitors: Genesis, Legal and Organisational Framework, Development Proces

European Agenda on Migration presented by the Council of Europe in 2015 revealed a necessity for amendment of the Frontex Regulation, in order to enhance its role in supporting Member States with regards to forced-returns. As underlined, all operational activities of the Agency shall be applied in respect of fundamental rights. European Border and Coast Guard Regulation adopted in 2016 provided for an obligation for all of forced-return operations coordinated or organised by Frontex to be me monitored. At the same time Frontex pool of forced-return monitors was set up with this view to support national monitoring systems. Through in-depth legal analysis of binding EU laws on forced-returns the author elaborates on the genesis, legal and organisational framework as well as on the development of Frontex pool of monitors.
Managing Travellers’ Predicted Future Travel Behaviour in a post-COVID-19 World: A Tourism Supplier Perspective
Authors: Kruger Martinette , Viljoen Adam
Published: September 2021

This research aims to assess the influence of COVID-19 on the travel and tourism industry from a supply-side perspective. More specifically, this research identifies the influential determinants to help manage tourists (main target markets') predicted behaviour and changes in travel patterns due to COVID-19. The exploratory research made use of an online questionnaire. The questionnaire's link was posted on a social media page in 2020, and a convenience snowball sampling method was used to gain access to travel and tourism suppliers. 111 responses were obtained. The multivariate analysis involved exploratory factor analyses (EFA) in identifying the dependent (tourists future travel behaviour) and the independent variables [suppliers’ initiatives to connect with their target market(s) during the pandemic, the predicted management and marketing strategies the travel and tourism industry will adopt after COVID-19 and perceptions regarding the future of the travel and tourism industry (in a post-COVID world)] that were included in regression analyses. A set of linear regression analyses was performed to show whether there is a significant relationship between the factors that may provide additional guidelines for managing travellers’ predicted travel behaviour due to COVID-19. This research provides valuable insights into the strategies the various sectors within the tourism industry implement and plan to adopt to regenerate their tourism operations post COVID-19. Moreover, since this research is primarily focused on the supply-side (tourism suppliers), the sectoral feedback is valuable in streamlining national tourism industry guidelines post-COVID-19.
K-Mean Clustering Analysis and Logistic Boosting Regression for Rock Facies Characterization and Classification in Zubair Reservoir in Luhais Oil Field, Southern Iraq
Authors: Albuslimi Mohammed
Published: September 2021

Identifying rock facies from petrophysical logs is a crucial step in the evaluation and characterization of hydrocarbon reservoirs. The rock facies can be obtained either from core analysis (lithofacies) or from well logging data (electrofacies). In this research, two advanced machine learning approaches were adopted for electrofacies identification and for lithofacies classification, both given the well-logging interpretations from a well in the upper shale member in Luhais Oil Field, southern Iraq. Specifically, the K-mean partitioning analysis and Logistic Boosting (Logit Boost) were conducted for electrofacies characterization and lithofacies classification, respectively. The dataset includes the routine core analysis of core porosity, core permeability, and measured discrete lithofacies along with the well-logging interpretations include (shale volume, water saturation and effective porosity) given the entire reservoir interval. The K-Mean clustering technique demonstrated good matching between the vertical sequence of identified electrofacies and the observed lithofacies from core description as attained 89.92% total correct percent from the confusion matrix table. The Logit Boost showed excellent matching between the recognized lithofacies from the core description and the predicted lithofacies through attained 98.26% total correct classification rate index from the confusion matrix table. The high accuracy of the Logit Boost algorithm comes from taking into account the non-linearity between the lithofacies and petrophysical properties in the classification process. The high degree of lithofacies classification by Logit Boost in this research can be considered in a similar procedure at all sandstone reservoirs to improve the reservoir characterization. The complete facies identification and classification were implemented with the programming language R, the powerful open-source statistical computing language.
Malware: The Never-Ending Arm Race
Authors: Menendez Hector David
Published: September 2021

"Antivirus is death"' and probably every detection system that focuses on a single strategy for indicators of compromise. This famous quote that Brian Dye --Symantec's senior vice president-- stated in 2014 is the best representation of the current situation with malware detection and mitigation. Concealment strategies evolved significantly during the last years, not just like the classical ones based on polimorphic and metamorphic methodologies, which killed the signature-based detection that antiviruses use, but also the capabilities to fileless malware, i.e. malware only resident in volatile memory that makes every disk analysis senseless. This review provides a historical background of different concealment strategies introduced to protect malicious --and not necessarily malicious-- software from different detection or analysis techniques. It will cover binary, static and dynamic analysis, and also new strategies based on machine learning from both perspectives, the attackers and the defenders.
Practical training the development of scientific thinking
Authors:   ", Chesaru Nicoleta ,   Delta Dunării",   Economic College
Published: September 2021

The main objective of this paper is to bring a fair approach on the subject of integrating the modern digital technology in education. We seek to find the best type of involvement in transforming the education process into a digital education that will cover an equilibrated and healthy view of what are the necessities of the current times and what are excesses that could be harming for the educational purpose.
Popular synchronous, asynchronous and hybrid e-learning systems
Authors:   ", Zubenschi Ecaterina ,   Ion Creanga",   State Pedagogical University
Published: September 2021

Online education requires careful thinking about how students and teachers are equipped to change traditional education to the new digital technology requirements. Digital learning management systems, communication tools and e-learning platforms play a crucial role in the new conditions of online learning. Programs and applications can help learning providers manage, plan, deliver, and track learning. Teachers, in addition to specialized skills in the field of teaching subjects, are presented with new skills of knowledge and management of digital tools. Digital competence is one of the eight key competences, materializing in the confident and critical use of the entire range of information and communication technologies for information, communication and problem solving in all areas of life. The use of digital technologies and living speech, represents a whole didactic creation, which individualizes the presented discourse to become an art in shaping the souls of the young generation.
Psychopedagogical conditions for optimizing online learning
Authors:   ", Raileanu Olga ,   Ion Creanga",   State Pedagogical University
Published: September 2021

This article reflects the importance of highlighting the conditions for optimizing online learning, the defining aspects of the challenges to which the educational process has been subjected. In the same context, the possibilities of forming the resilience of the educational system in the face of the changes caused by the Covid pandemic 19 are described. It addresses the issue of streamlining online learning by capitalizing on the digital skills of learners, more efficient use of resources in the environment in which the child lives and learns, the possibilities of community institutions and media, but also the use of distance/ online learning technologies for special or unpredictable situations.
Scientific thinking of teachers in the context of lifelong learning
Authors:   Bechet Theoretical High School, Ionescu Mariana
Published: September 2021

Lifelong learning is the common development process for consolidating society and knowledge that involves learning key skills that stimulate the development of strategies to develop psychological assistance and find effective and original solutions in personal, professional and social life. Becoming a priority of the global education system and a European priority, the lifelong learning process is approached not only as a personality movement from general/ university/ postgraduate education, but a harmonious one of continuous personality updating. Lifelong learning, being a vital component of European educational policies, aims to stimulate the competitiveness, social inclusion, active citizenship, career guidance and personal development of all people, including those with disabilities. Teachers represent the most active social group of lifelong learning, professional development, therefore, in order to progress consistently and significantly, along this spiral, they must turn to that court - one of the specific human which governs the upward movement - moral conscience through creativity and proactivism.
The Effectiveness of a Group Motor Skill Intervention Program in Children with Developmental Coordination Disorder: Program Frequency Matters.
Authors: Caçola Priscila , Ibana Melvin , Romero Michael , Chuang Jennifer
Published: September 2021

Purpose: The purpose of this study was to investigate the effects of two group programs on visual-motor integration, motor proficiency, gross-motor skills, and parental perception of motor difficulties in children with developmental coordination disorder (DCD). We compared whether the frequency of two programs (10 one hour sessions - once/week for 10 weeks verses 24 one hour sessions – twice/week for 12 weeks) produced different changes in motor skills. Methods: Children in the two programs were assessed before and after each program with the MABC-2, DCD-Q, BOT-2, Beery-VMI-6, and the TGMD-2 assessments. The emphasis of the programs was on group activities that required collaboration while performing skills that utilized upper-body coordination, balance, and fine-motor abilities. Results: After the 24-session intervention program, results revealed significant improvements in the Manual Coordination and Total Score of the BOT-2 (ps < .05), and parents reported significantly higher scores for all categories of the DCD-Q (ps < .05). No significant changes were observed after the 10-session once/week intervention program. Conclusions: We conclude that a (24 one-hour sessions- twice a week for 12 weeks) group intervention program can be an effective intervention method for improvement of motor skills in children with DCD. We recommend that allied health professionals consider the group intervention as a feasible way to promote more frequent sessions to children with DCD.
Is Professionalism Important in Physician Assistant Education?
Authors: Ryan Susan
Published: September 2021

Purpose: This study was designed to demonstrate the importance of a formal professionalism curriculum in physician assistant (PA) education. The PA concept arose from the medical profession, and PA education was designed to follow the medical model of education. Courses have been mandated by the Accreditation Council for Graduate Medical Education (ACGME) to include professionalism. Just as in the curriculum in medical schools, PA educators have been allowed to create their own professionalism curricula. The American Academy of Physician Assistants (AAPA) and the Accreditation Review Commission on Education for the Physician Assistant (ARC-PA) have mandated that professionalism and ethics must be included in PA education. To address this need, a professionalism curriculum for first year PA students was created that combined standards of professionalism that are taught in medical school with those from the PA profession. Method: Sixty-four students enrolled in their first year of a master’s degree PA program were asked to voluntarily participate in a two-part survey to assess their knowledge of professionalism. The initial survey was administered prior to any formal education in professionalism. The same survey was repeated following the completion of the professionalism curriculum. The design of the survey was cross sectional and consisted of close ended questions. A Likert scale was utilized for responses, allowing for statistical analysis and comparison. Results: Sixty-three of 64 students completed both surveys. Results did not demonstrate a statistically significant improvement in knowledge of professionalism. Student evaluations were overwhelmingly positive, as was their participation in group discussions. Conclusions: Professionalism did not significantly improve. The lack of statistical significance may have referred to the lack of reliability in the findings but did not indicate the curriculum was effective or ineffective. It may have been wiser to continue professionalism education throughout the didactic year, incorporating case studies and simulation exercises.
The Importance of Including Co-Factor Information when Reporting Resting Heart Rate
Authors: Hart John
Published: September 2021

Resting heart rate, sometimes referred to as resting pulse rate (RPR) is taken for various reasons in the various health care professions. As with many physiological tests, there are a number of basic factors that can affect RPR, such as gender and position of the patient during measurement. In most papers, these basic factors are included but in some they are not. If such information is lacking, the meaningfulness of the reported RPR is diminished. The purpose of this manuscript is to highlight the importance of including such information when reporting on RPR data.
Outcome Measures for Mild Balance and Cognitive Decline in a Pre-Old Adult: A Case Report
Authors: Chan Melissa , Rone-Adams Shari
Published: September 2021

Background and Purpose. Early detection and treatment of age-related decline, particularly balance and cognition, are increasingly being emphasized in current research. However, the majority of research on older adults focuses on participants who are 65 years and older. For individuals who are 60-64 years old, this is an age range where they may or may not be considered an older adult. This poses a problem applying the results of these studies to pre-old adults to accurately diagnose, measure and classify risk in the areas of cognition and balance. Case Description. The patient is a 61-year-old woman with a clinical diagnosis of osteoporosis. She has had 5 falls and near-falls in the past year. She also experiences memory problems, which sometimes affects her ability to plan and organize her schedule. She is otherwise well, with no limits to participation. Outcomes Assessment. Frequently used clinical tools to assess for mild balance and cognitive deficits were performed in order to detect diagnosis and/or classify risk. A total of 14 tools related to balance and falls, and 4 tools related to cognition were chosen. Results. Of the assessment tools used, only the Mini Balance Evaluation Systems Test (Mini BESTest), High Level Mobility Assessment Test (HiMAT), and the Falls Efficacy Scale- International (FES-I) were able to identify and classify risk of fall and/or balance deficits. Of the cognitive tools performed, only the Montreal Cognitive Assessment (MoCA) produced abnormal results, suggesting cognitive decline. Conclusions. Many of the frequently used clinical assessment tools were unable to identify falls history and balance deficits in this patient. In view of the lack of sensitivity in balance assessment tools in pre-old adults and the multiple factors associated with falls risk, it is difficult to conclusively determine if she does have balance deficits and to quantify her risk of future falls. Cognitive screening in this patient suggests that an algorithmic approach using the Mini Mental State Examination (MMSE) and the MoCA may be effective in screening for mild cognitive impairment (MCI). More research should be directed towards the development and validation of sensitive instruments to detect mild balance deficits and screening for MCI, especially in the pre-old adult.
An Investigation of Service Providers’ understanding, perspectives and implementations of the Transdisciplinary model in Early Intervention settings for Children with Disabilities
Authors: Fitzmaurice Eimear , Richmond Janet
Published: September 2021

Purpose: The transdisciplinary practice model is currently being promoted as best practice in early intervention therapy for children with disabilities. However, supporting literature is limited. Thus, the question is asked, “What are service providers' understanding and perception of the transdisciplinary model in early intervention settings for children with disabilities?” Method: A systematic review was carried out using the Preferred Reporting Items for Systematic Reviews. An electronic search was conducted via six databases. Eight articles were selected. Results: Four studies predominantly focused on service providers’ perspectives of the model using semi-structured interviews or surveys. Many studies were of adequate to low quality, and the methods of implementing the transdisciplinary approach varied across organisations. It is therefore difficult to draw valid conclusions based on service provider’s viewpoints of the model. Conclusions: This review attempted to determine if the transdisciplinary model is best practice. The inconsistencies in the transdisciplinary teams indicates that overall, the general understanding of the model and its framework amongst organisations is poor. Further research is needed to establish service providers’ understanding of the model and how transdisciplinary teams are functioning since the introduction of the National Disability Insurance Scheme.
Perceptions of Non-university Affiliated Dietetic Internship Program Directors Regarding Education Requirements to Obtain a Master’s Degree as an Entry-level Dietitian
Authors: Sullivan Abigail , Heuberger Roschelle
Published: September 2021

Purpose: The Commission on Dietetic Registration announced that entry-level eligibility requirements to become a registered dietitian would increase to include obtaining a Master’s degree. The objective of this study was to explore perceptions of non-university affiliated dietetic internship program directors regarding proposed education requirements. Methods: Directors participated in a phone survey of structured questions related to the topic. The population of focus was non-university affiliated dietetic internship program directors. Results: Program directors expressed viewpoints of positive, negative, and mixed regarding the increase in education requirements. Diversity and autonomy were among concerns expressed by program directors. Conclusion: The research found that this subset of stake holders remains conflicted with the decision by the Commission on Dietetic Registration that a Master’s degree would be the entry-level requirement to become a registered dietitian.
NGHIÊN CỨU SINH TRƯỞNG, PHÁT TRIỂN, NĂNG SUẤT VÀ CHẤT LƯỢNG CỦA MỘT SỐ GIỐNG ĐẬU XANH TẠI THỪA THIÊN HUẾ
Authors:   Trường Đại học Nông Lâm, Đại học Huế, Phan Thị Phương Nhi , Trần Đăng Tuấn Vũ ,   Trường Đại học Nông Lâm, Đại học Huế, Nguyễn Thị Thúy ,   Trường Đại học Nông Lâm, Đại học Huế
Published: September 2021

Nghiên cứu được tiến hành trên 9 giống đậu xanh, nhằm tuyển chọn giống có khả năng sinh trưởng, phát triển tốt, năng suất cao, chất lượng và chống chịu tốt, thích nghi với điều kiện sinh thái tại tỉnh Thừa Thiên Huế. Thí nghiệm bố trí theo phương pháp khối hoàn toàn ngẫu nhiên (RCBD), mỗi giống là 1 công thức và có 3 lần nhắc lại. Nghiên cứu được tiến hành trong vụ Xuân 2020, tại Trung tâm Nghiên cứu và Dịch vụ Nông nghiệp, khoa Nông học, trường Đại học Nông Lâm, Đại học Huế. Các chỉ tiêu nghiên cứu thực hiện theo Quy chuẩn về khảo nghiệm giá trị canh tác và giá trị sử dụng của giống đậu xanh. Kết quả nghiên cứu cho thấy các giống đậu xanh có thời gian sinh trưởng từ 77 đến 83 ngày, khả năng sinh trưởng phát triển tốt, có khả năng chịu hạn từ trung bình đến tốt, chống đổ tốt. Năng suất lý thuyết và năng suất thực thu của các giống biến động khá lớn (14,02 - 21,04 tạ/ha và 8,64 - 15,87 tạ/ha). Hàm lượng protein tổng số của các giống biến động từ 15,16 đến 24,88%, hàm lượng tinh bột từ 44,42 đến 49,11% và hàm lượng lipid dao động từ 2,07 đến 2,43 %. Qua đánh giá các chỉ tiêu nghiên cứu tuyển chọn được hai giống có triển vọng là đậu xanh Mỡ và NTB02.
The pathway integral operator involving extension of k-Bessel-Maitland function
Authors: AHMAD Moin , PORWAL Saurabh
Published: September 2021

It has a wide application in the problem of physics, chemistry, biology, engineering and applied sciences. The theory of Bessel functions is intimately connected with the theory of certain types of differential equations. A detail account of applications of Bessel functions are given in the book of Watson [26]. In this present paper, we establish generalized extension of k-Bessel-Maitland function involving pathway integral operator. we obtain certain composition formulas with pathway fractional integral operators. Further more, Some interesting special cases involving Bessel
functions, generalized Bessel functions, generalized Mittag-Leffer functions, generalized k-Mittag-Leffer functions are deduced.\\
Railway Track Failure Detection System
Authors:   Assistant Professor, Mechanical Department, Don Bosco College of Engineering, Fatorda, Goa, India, Marathe Suraj
Published: September 2021

Indian railway is one of the largest networks in the country. Its motto is “the life line of the country”, and the main transport is completed by the railways of the country. Railroad is one of the cheapest and safest means of transport, but there are also certain accidents on the railroad. 60% of accidents are caused by road failures or the formation of cracks in the road. Today’s rail systems involve manual track inspection, which is cumbersome and not entirely effective. However, the detection and correction of track defects is a problem for all railway companies in the world. The objective of this research work is to detect railroad track failures with the help of ultrasonic sensor and show the exact location of the crack on web app by using GPS module.
Problems With the Procedure for Granting Annual Leave and Suggestions for Their Solution
Authors:   Independent Researcher, University of Public Safety, Madrakhimova Guljakhon Ruzimboy qizi
Published: September 2021

The article examines and analyzes the procedure for granting annual leave to employees, problematic aspects of the application of legislation in this area, and also proposes proposals for their elimination based on the experience of foreign countries.
Inhibition of Germ Tube Formation in Mucor & Candida by JRK’s DCOD
Authors:   Asst. Manager- Dr. JRK’s research and Pharmaceuticals Pvt Ltd, No.18 & 19, Perumal koil street, Kunrathur, Chennai-600069., G.V. Amruthavalli
Published: September 2021

JRK’s DOCD is a proprietary siddha medicine, indicated for prevention of co-morbidities of diabetes. Earlier studies on the product has proven its effect in boosting the phagocyte mediated immunity. In the current study the ability of the product in preventing pathogenicity of fungi is evaluated. Germ tube formation is proven to increase the pathogenicity of the fungi than the spores alone. For this different species of fungi i.e., Candida albicans, 2 isolates of Candida dubelensis and three isolates of Mucor and 1 isolate of Rhizopus are taken. These fungal cultures when treated with the JRK’s DCOD, there is an inhibition of germ tube formation compared to control. Complete study details are presented in the paper.
Kashmir dispute: Emerging complexities after abrogation of Article 370
Authors: Ali Rizwan , Mustafa Usman
Published: September 2021

Kashmir dispute is one of the contentious issues between India and Pakistan since their inception as independent states in 1947. This paper addresses this dispute that how it has been a primary cause of contention between India and Pakistan. How is it a huge humanitarian crises in the South Asia and ultimately the cause of a bulk of defence expenditures by India and Pakistan. Nonetheless, both the countries realize that the problem of Kashmir can and should be resolved through peaceful negotiations to reach a non-military solution. Both the states continue giving it a central importance in their internal and external policies. This resultant peaceful cooperation between the two nuclear powers is a central part of complex interdependence theory, which is used in this paper for analysing the issue. Thus, the paper investigates the Kashmir conflict and the cooperation between India and Pakistan to seek a peaceful resolution. The paper qualitatively assesses the situation emerged in the Kashmir after the abolishment of Article 370, for which some key people are interviewed. The findings show that the unilateral abrogation of the article 370 by the Modi government that changed the status of Kashmir further intensified the conflict and undermined the peaceful efforts made so far.
KEMAMPUAN MEMBEDAKAN IMBUHAN DENGAN KATA DEPAN DALAM KALIMAT BAHASA INDONESIA SISWA KELAS X IPA MAN LOMBOK BARAT TAHUN PELAJARAN 2020/2021
Authors: Jayadi Usman , M Muhsan
Published: September 2021

Imbuhan dalam sebuah kalimat dapat mengubah makna, jenis, dan fungsi sebuah kata dasar atau bentuk dasar menjadi kata lain yang fungsinya berbeda dengan kata dasar atau bentuk dasarnya. Imbuhan yang  mana yang digunakan tergantung pada keperluan penggunanya didalam pertuturan lewat kalimat. Untuk keperluan pertuturan itu terkadang sering pula siswa salah dalam menggunakan imbuhan (afiks) dalam kalimat bahasa Indonesia, sehingga mengakibatkan terjadi kontaminasi (kerancuan makna), ambiguitas,  tidak logis, tidak efektif, tidak normatif dan lain-lain. Demikian halnya dengan penggunaan kata depan dalam kalimat bahasa Indonesia. Kadang-kadang kata depan dijadikan sebagai imbuhan dan imbuhan dijadikan kata depan dalam kalimat bahasa Indonesia. Permasalahan ini tampak pada cara menulis kalimat dan mengerjakan soal-soal dalam bahasa Indonesia pada siswa kelas X IPA MAN Gerung. Penelitian ini berorentasi pada masalah bagaimana siswa dapat membedakan imbuhan dengan kata depan dalam kalimat bahasa Indonesia. Tujuan penelitian ini adalah untuk mendeskripsikan kemampuan membedakan imbuhan dengan kata depan dalam kalimat bahasa Indonesia siswa kelas X IPA MAN Gerung tahun pelajaran 2020/2021. Metode penentuan subjek yang digunakan adalah metode populasi mengingat jumlah siswa kelas X IPA MAN Gerung kurang dari 100 orang. Metode pengumpulan data meliputi; metode observasi, metode tes, dan metode dokumentasi. Sedangkan metode analisis data menggunakan hitungan statistik. Hasil analisis data menunjukan bahwa secara umum rata-rata peningkatan pembelajaran membedakan imbuhan dengan kata depan dalam kalimat bahasa Indonesia siswa kelas X IPA MAN Gerung tahun pelajaran 2020/2021 termasuk dalam kategori tinggi yaitu rata-rata (M) kemampuan individu dalam penggunaan imbuhan = 84,20 dan kemampuan kelompok = 84,20, sedangkan kemampuan individu dalam penggunaan kata depan rata-rata = 83,84 dan kemampuan kelompok = 83,84. Indeks Prestasi Kelompok yang dicapai sebesar 83,96. Termasuk kategori tinggi bila dibandingkan dengan target kurikulum dengan daya serap secara klasikal miniumal 75. Sedangkan kemampuan secara individu membedakan imbuhan dengan kata depan rata-rata siswa di atas KKM = 66,67 atau 100% tuntas.
HUBUNGAN KEPEMIMPINAN KEPALA MADRASAH DAN PRESTASI KERJA GURU DENGAN KEMAJUAN MADRASAH ALIYAH SE-KABUPATEN SURAKARTA
Authors: Eka Yuda Wibawa Angga
Published: September 2021

Penelitian ini bertujuan untuk mengetahui: (1) hubungan antara kepemimpinan Kepala Madrasah dengan kemajuan Madrasah Aliyah se-Kabupaten Surakarta, (2) hubungan antara prestasi kerja guru dengan kemajuan Madrasah Aliyah se-Kabupaten Surakarta, dan (3). hubungan antara kepemimpinan Kepala Madrasah dan prestasi kerja guru secara bersama dengan kemajuan Madrasah Aliyah se-Kabupaten Surakarta. Penelitian ini menggunakan pendekatan studi korelasional. Data yang digunakan adalah data primer dengan cara menyebarkan kuesioner kepada 30 orang sampel penelitian yang terdiri dari kepala madrasah dan guru Madrasah Aliyah se-Kabupaten Surakarta. Hasil pengumpulan data selanjutnya dianalisis menggunakan teknik analisis korelasi dan analisis regresi dengan bantuan Program IBM SPSS (Statistical Product and Service Solution) Statitics versi 21. Hasil penelitian ini menunjukkan bahwa: (1) ada hubungan yang signifikan antara kepemimpinan kepala madrasah dengan kemajuan madrasah sebesar 95,3%, sedangkan korelasi partial antara kepemimpinan kepala madrasah dengan kemajuan madrasah sebesar 64%, dan kepemimpinan kepala madrasah akan memberikan kontribusi terhadap kemajuan Madrasah Aliyah se-Kabupaten Surakarta sebesar 90,7%; (2) Ada hubungan yang signifikan antara prestasi kerja guru dengan kemajuan madrasah sebesar 98,8%, sedangkan korelasi partial antara prestasi kerja guru dengan kemajuan madrasah sebesar 86,1%, dan prestasi kerja guru akan memberikan kontribusi terhadap kemajuan Madrasah Aliyah se-Kabupaten Surakarta sebesar 97,7%; serta (3) Ada hubungan yang signifikan secara bersama antara kepemimpinan kepala madrasah dan prestasi kerja guru dengan kemajuan madrasah sebesar 98,8%, kepemimpinan kepala madrasah dan prestasi kerja guru akan memberikan kontribusi secara bersama terhadap kemajuan Madrasah Aliyah se-Kabupaten Surakarta sebesar 97,7%, sedangkan persamaan garis regresinya adalah: Y = 59,301 + 0,154 X1 + 0,571 X2.
IMPLEMENTASI PLATFORM DIGITAL SEBAGAI MEDIA PEMBELAJARAN DARING DI MI MUHAMMADIYAH PK KARTASURA PADA MASA PANDEMI COVID-19
Authors: Eka Yuda Wibawa Angga
Published: September 2021

Penelitian ini bertujuan untuk menjelaskan pemanfaatan berbagai platform digital sebagai media pembelajaran pada masa pandemi covid-19 di MI Muhammadiyah PK Kartasura. Penelitian ini merupakan bagian penting atas adanya perubahan proses kegiatan pembelajaran tatap muka menjadi pembelajaran daring/online dengan bantuan beberapa platform digital yang dikeluarkan Kementerian Pendidikan dan Kebudayaan sebagai media pembelajaran. Metode yang digunakan pada penelitian ini adalah metode kajian pustaka. Data penelitian yang dikumpulkan berupa data studi literatur. Sumber data yang digunakan diambil dari berbagai referensi yang relevan dengan penelitian seperti buku, jurnal penelitian, dan manual book atau buku panduan penggunaan beberapa platform digital. Teknik analisis data yang digunakan adalah analisis isi (content analysis), yaitu mengkaji informasi utama yang dibahas dalam referensi, mengaitkan dengan setiap topik yang dibahas, kemudian pemetaan konsep dalam bentuk perbandingan dari setiap data penelitian. Hasil dari penelitian ini diharapkan memberi kontribusi dalam memudahkan sekolah, guru, dan siswa memanfaatkan beberapa platform digital yang dikeluarkan Kementerian Pendidikan dan Kebudayaan sebagai media pembelajaran selama covid-19.
A Review on Five Membered Nitrogen Containing Heterocyclic Compounds with Various Biological Activities
Authors: Joseph incy , Sanu Meenu C , Chacko Divya
Published: September 2021

Heterocyclic compounds are a highly valuable and unique class of compounds. Different heterocyclic analogues have been evaluated
for their diverse biological activities. Five membered heterocyclic compounds possess various pharmacological activities. Among them
Nitrogen containing five membered heterocyclic compounds have crucial place in medicinal chemistry. This paper aims to review on
the pharmacological activities of five membered nitrogen containing heterocyclic compounds.
Clinical Applications and Properties of Calcium Citrate Malate
Authors: Balakrishnan Angarika , Raheema Naushin , Kaur Navnoor , Chakrabarty Nilasha , Mumtaz Shakila
Published: September 2021

This article is an examination of the Clinical applications and properties of Calcium Citrate Malate. The scientific development and subsequent need to understand the properties of Calcium Citrate Malate, that make it an excellent candidate for treatment of
disorders in various clinical domains, continues to influence the researchers all over the globe today. This article examines the
research done and published by researchers and scientists. Consideration of current trends and data in scientific queries and
demonstrates further aspects of the clinical applications and properties of Calcium Citrate Malate. Additionally, this article explores options for the role of Calcium Citrate Malate supplementation in dental care, to prevent tooth loss, erosion and abrasion, in Immunology as a critical signal for inflammation, in joints to treat osteoarthritis and in nephrology to tackle the renal stone problem.
A Review Article on Phytochemical Investigation and Pharmacological Activity of Various Parts of Dalbergia sissoo
Authors: Soni Pooja , Kumar Prashant
Published: September 2021

Current study discussing the ethnobotanical importance of the different part of the plant Dalbergia sissoo its pharmacological activity and various formulation. Nature is like a treasure of medicine. From last thousands year nature give us several type of medicines which we use for the treatment of different type of diseases and valetudinarism. Dalbergia sissoo is one the most crucial/significant plant with full of medicinal attribute. Dalbergia sissoo (Fabaceae) has reported to possess different type pharmacological activity such as antinociceptive activity, anti-coagulant activity, antibacterial activity, anti-inflammatory activity, memory enhancing activity, antiulcer activity, nephro-protective activity, anti-spermatogenic activity, analgesic activity, antipyretic activity, antitermitic activity, antilithiatic activity, antidiabetic activity, anthelmintic activity, immunomodulation activity and so on. This study divulging the medicinal important and all pharmacological action of the different part of the plant Dalbergia sissoo.
Co-morbid Gestational Diabetes and PCOS: Risks and Management
Authors: M. Dheepthi , B. Naveena , V.M. Jeevika , C. Sowmya
Published: September 2021

Diabetes is emerging global burden and is defined as chronic metabolic disorder that results in elevated level of blood glucose and is due to beta cell destruction. Gestational diabetes is the type of diabetes that occurs in women during pregnancy or first recognized at the Gestational period. The prevalence of Gestational diabetes is increasing tremendously in developing countries. Approximately 2 to 14% of pregnancy is diagnosed with Gestational diabetes and 90% of all Gestational diabetes is reported from low- and middleincome countries. Of these North Africa has the highest prevalence followed by South Asia. The chance of developing type 2 diabetes is 7 times higher in women with previous history of Gestational diabetes and also it involves in increasing the risk of cardio metabolic disorders in later life. Gestational diabetes results from various complex interactions of environmental, genetic and maternal factors. Polycystic ovarian syndrome (PCOS), a major cause of infertility in women causes hormonal abnormalities and is also associated with insulin resistance. There exists a relationship between Gestational diabetes and PCOS stating that PCOS increase the risk of Gestational diabetes since insulin resistance is common factor in both. It is observed that the risk of Gestational diabetes is threefold higher n women with PCOS. Both PCOS as well as Gestational diabetes affects the quality of life of women due to many pathological changes. Life style modification is essential for management of PCOS and Gestational diabetes. Insulin therapy is recommended to treat hyperglycemic condition during pregnancy.
Recent Advances in the Cancer Drug Delivery: Nanocarrier Approach
Authors: Prashar Deepak , Poonam Poonam
Published: September 2021

The present review work tries to explore the present status of the nano carriers in the delivery of anti cancer drugs. The shortcomings
associated with the anticancer drugs like poor solubility, multiple resistance and less bioavailability is been investigating using
different nano formulations. The recent advance work on nanoparticles for the delivery of anti tumor drugs is focused along with the different patents available. The different technologies available in the present scenario for the delivery of anti-cancers drugs are being highlightened.
Prevalence and Antibiogram of Healthcare-Associated Methicillin-Resistant Staphylococcus aureus (HA-MRSA) in Ebonyi State, Nigeria
Authors: E.G Ukpai , E. I. Chukwura , I.B Moses , E.N Ugbo , N.B Agumah , O.D Okata-Nwali , V.N Anakwenze , C.C. Nnabugwu , B.O Onodagu , O.E Udu-Ibiam , G. I Ogu
Published: September 2021

Methicillin resistant Staphylococcus aureus (MRSA) remains a major cause of both community and healthcare-associated infections.
This study was designed to determine the prevalence and antibiogram of healthcare-associated MRSA (HA-MRSA) in Ebonyi State, Nigeria. A total of 315 clinical samples were obtained from government-owned and private-owned healthcare facilities (HCFs) in Ebonyi State. S. aureus were characterized and identified based on standard microbiological procedures. MRSA isolates were detected using Kirby-Bauer disc diffusion technique with oxacillin (1µg) and cefoxitin (30µg) antibiotic discs. HA-MRSA prevalence frequency of 41.5% was recorded in the HCFs in Ebonyi State. Frequency of HA-MRSA isolation was highest in urine samples (51.1 %). Furthermore, a higher HA-MRSA isolation rate (63.6%) was observed in clinical samples from private HCFs than the government HCFs (28.4%). HA-MRSA were highly resistant to penicillin (99.4 %), ceftazidime (96.4 %), and erythromycin (90.6%), but highly susceptible to ciprofloxacin and gentamycin. A mean MARI index of 0.71 was observed in this study with 96.5 % > 0.2. In conclusion, prevalence of HA-MRSA was quite alarming in our study area. Therefore, more proactive measures must be taken to curb this public health menace before it escalates beyond control. The use of therapeutics such as ciprofloxacin and gentamycin is strongly recommended for the treatment of MRSA infections in our study area.
Evaluation of in vivo Hepatoprotective activity of Mimosa rubicaulis (LAM.) against CCL4 Induced Liver Toxicity
Authors: Tamboli Ashpak M. , Wadkar Kiran A.
Published: September 2021

The current study was conducted to assess the hepatoprotective activity of different extracts of M. rubicaulis (Lam.) at (200 and 400
mg/kg) doses b.w. against CCl4 induced liver intoxication in Albino Wistar rats. Male or female Wistar rats about 150 and 200 gm body
weight were selected for present study. The animals were divided into thirteen groups, six rats in each group. The extracts and
Silymarin-treated animal groups significantly reduced the activities of various biochemical markers such as SGPT, SGOT, ALP, and TB
which were elevated by carbon tetrachloride (CCl4) intoxication. The extracts of M. rubicaulis (Lam.) showed a dose dependent
hepatoprotection activity. Among all the extracts, ethanolic extract produced maximum hepatoprotection (SGPT-83.15 %, SGOT76.82%, ALP-79.33%, TB-80.00%) at a 400mg/kg dose. After CCl4 administration, the levels of hepatic-antioxidant enzymes such as
Glutathione (GSH) and Catalase (CAT) were reduced, whereas the level of hepatic lipid peroxidation (-LPO) increased. These hepatic
antioxidant enzymes were also restored to normal levels by extracts and Silymarin treatment. The results of the present investigation
indicate that all the extracts of M. rubicaulis (Lam.) possess hepatoprotective activity which may be due to the presence of various chemical constituents.
Effect of Nebivolol on MPTP Induced Parkinson’s Disease in Mice
Authors: K Karthigadevi. , S Anbazhagan. , Sudheer Kumar Jajjara Gopi , S Kavimani.
Published: September 2021

Parkinson’s disease is the major neurodegenerative disorder, which is due to the loss of dopaminergic neurons in the brain and results
in bradykinesia, rigidity, tremor and instable posture. Oxidative stress, Inflammation, Apoptosis has been implicated in the molecular etiopathogenesis of Parkinson disease. In the present study, Nebivolol, a Cardioselective ?-blocking agent which is also reported as an antioxidant, anti-inflammation, anticonvulsant, inhibition of apoptosis and protective effects on gastric ulcer. Hence, nebivolol has been tested for its antiparkinson activity against 1-Methyl, 4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) induced model of Parkinson disease in mice. From this study, the result shown that the nebivolol exerts its beneficial effect against MPTP induced Parkinson’s disease by virtue of its antioxidative, anti-inflammatory and by increases the Dopamine levels in the brain.
Pharmacological Activities of Celastrus paniculatus Willd.: A Review
Authors: Choudhary Arpita , Soni Pooja
Published: September 2021

Current review includes medicinal importance and various pharmacological activities of Celastrus paniculatus Willd. Celastrus
paniculatus Willd. belongs to Celastraceae family. It is a plant of medicinal importance and is being used in Ayurveda from a very long time to treat different disorders mainly brain related disoders. It is also known as ‘Tree of life’. It is commonly known as Malkangani and Jyothishmati in hindi and sanskrit respectively. Different studies have proved that it has various pharmacological activities which includes neuroprotective activity, rejuvenative activity, cardiovascular activity, analgesic activity, anti-inflammatory activity, antiinfertility activity, antioxidant activity, free radical scavenging activity anti-arthritic activity etc. It has been proved in various studies that Celastrus paniculatus willd. is a potent drug for improving memory and intellect. This manuscript reviews current information on various pharmacological and medicinal activities of Celastrus paniculatus.
Chronopharmaceutical Drug Delivery Systems: A Comprehensive Review
Authors: Gupta Vipin , Kumar Prashant
Published: September 2021

Chronopharmaceutical drug delivery systems release drug at a rhythm that ideally matches the biological requirement of a given
disease therapy or prevention. The sound knowledge of the biological processes and their functions utilized in biomedical and
pharmaceutical sciences is necessary for effective design and evaluation of pharmaceutical dosage forms. Circadian phase master the circadian clock of the body, the supra chiasmatic nucleus is known to regulate the endogenous circadian rhythms present inside the human body and the peak evidences of some diseases are reported as per circadian rhythm. The secretion of melatonin, a hormone, released by the pineal gland during darkness, help to reset the internal clock, which regulates the timing of different body functions. In certain diseases like asthma, airway resistance increases progressively in early morning, also release of adrenaline and noradrenaline in the morning causes rise in the blood pressure. In hypercholesterolemia, cholesterol synthesis is higher during the night time than day light; in diabetes mellitus blood sugar level is higher in the day time; myocardial insufficiency occurs early in the
morning, and many others. The present review addresses the approaches to chronopharmaceuticals, identifies existing technologies, and study of recent chronopharmaceutical drug delivery systems for management of various chronic diseases like diabetes, hypertension and various types of cancers according to the circadian rhythms of diseases in order to optimize therapeutic outcomes and reduce side effects. Recently chronopharmaceutical drug delivery systems are attaining huge importance in the field of
pharmaceutical technology for product development because they are proved to reduce dosing frequency, toxicity and also they
deliver the drug in particular disease as and when required considering the peak time of the disease, offering better patient
compliance.
Dissolution Enhancement of Flurbiprofen by Solid Dispersion Adsorbate Technique
Authors: Vaghela Sohansinh S. , Shah Samkit M. , Rathi Sanjesh G. , Shah Shrenik K.
Published: September 2021

Flurbiprofen solid dispersion Adsorbate (SDA) has been prepared using PEG 4000 and Poloxamer 188 as carrier and Neusilin as
adsorbent material. The SDA of Flurbiprofen was prepared by using Fusion method in various drugs to carrier ratios. The phase
solubility study concludes that both polymers have ability to improve the aqueous solubility of flurbiprofen. Pure API Flurbiprofen and final formulation samples of SDA are characterized by FTIR, DSC and X-ray diffraction spectroscopy. X-ray powder diffraction and DSC study indicated that the drug was present in amorphous form. FTIR study revealed that the characteristic peaks in spectra of pure Flurbiprofen are also present in spectra of SDA’s. Drug found compatible with the excipients. The highest improvement in solubility and in-vitro drug release were observed in solid dispersion prepared with Poloxamer 188 (F14) by fusion method. The increased dissolution rate of drug from solid dispersion adsorbates may be due to surface tension lowering effect of polymer to the medium and increased wettability and dispersibility of drug. Hence, F14 Solid dispersion adsorbates with the Poloxamer carrier in 1:2 ratio considered as most satisfactory among all solid dispersion adsorbates.