bluuebunny/crossref_metadata_2025 huggingface dataset:
A new winter wheat genetic resource harbours untapped diversity from synthetic hexaploid wheat.
Authors: Wright Tally I C , Horsnell Richard , Love Bethany , Burridge Amanda J , Gardner Keith A , Jackson Robert , Leigh Fiona J , Ligeza Aleksander , Heuer Sigrid , Bentley Alison R , Howell Philip
Published: October 2023

The allelic richness harboured in progenitors of hexaploid bread wheat (Triticum aestivum L.) is a useful resource for addressing the genetic diversity bottleneck in modern cultivars. Synthetic Hexaploid Wheat (SHW) is created through resynthesis of the hybridisation events between the tetraploid (Triticum turgidum subsp. durum) and diploid (Aegilops tauschii) bread wheat progenitors. We developed a large and diverse winter wheat Nested Association Mapping (NAM) population (termed the NIAB_WW_SHW_NAM) consisting of 3241 genotypes derived from 54 nested back-cross 1 (BC1) populations, each formed via back-crossing a different primary SHW into the UK winter wheat cultivar ‘Robigus’. The primary SHW accessions were created using 15 T. durum donors and 47 Ae. tauschii accessions that spanned the lineages and geographical range of the species. Primary SHW parents were typically earlier flowering, taller and showed better resistance to yellow rust infection (Yr) than ‘Robigus’. The NIAB_WW_SHW_NAM population was genotyped using a single nucleotide polymorphism (SNP) array and 27 Quantitative Trait Loci (QTLs) were detected for flowering time, plant height and Yr resistance. Across multiple field trials, a QTL for Yr resistance was found on chromosome 4D that corresponded to the Yr28 resistance gene previously reported in other SHW accessions. These findings highlight the value of the NIAB_WW_SHW_NAM population for genetic mapping and provide the first evidence of Yr28 working in current UK environments and genetic backgrounds. These examples, coupled with the evidence of commercial wheat breeders selecting promising genotypes, highlights the potential value of the NIAB_WW_SHW_NAM to variety improvement.
Saphenous Vein Tributaries in Sequential Vein Grafting for Coronary Artery Disease
Authors: Lanka Santh Prakash , Rai Guruprasad , Maramreddy Revanth , Bishnoi Arvind Kumar , Kumara Vijay , Sevagur Ganesh Kamath
Published: October 2023

Background
Sequential vein grafting is utilized to revascularize multiple distal vascular territories in patients with diffusely diseased coronaries undergoing repeat coronary artery bypass grafting (CABG). However, sequential vein grafting is technically challenging due to the side-to-side anastomosis. This study expands on the usage of saphenous vein tributaries in sequential vein grafting (tributary technique) and its outcomes at a single institution.
Methods
A retrospective observational chart review was conducted on patients who underwent the proposed technique in our institution over three years. The primary outcome variables included all-cause mortality and freedom from major adverse cardiovascular events (MACE). A descriptive analysis was conducted to express the continuous variables as mean and standard deviation and categorical variables as frequency and percentages.
Results
The study included 187 patients with a mean follow-up duration of 24.8 ± 10.0 months and operative mortality of 1.7%. A total of 131 patients remained symptom-free starting from the date of surgery, and four cardiovascular mortalities were reported during the follow-up period.
Conclusion
The tributary technique is feasible and can be a potential option in repeat CABGs requiring multiple grafts in patients with adequate vein calibre in lower limbs.
Association between intake of health foods/supplements and long-term care in the general elder population: the Yamagata cohort study
Authors: Miharu Maya , Suzuki Natsuko , Sho Ri , Osaki Tsukasa , Souri Masayoshi , Watanabe Masafumi , Ueno Yoshiyuki , Konta Tsuneo
Published: October 2023

Background: In recent years, the number of people who consume health foods and supplements has increased owing to growing health consciousness. However, the association between health foods/supplements intake and long-term care in the general elder Japanese remains unclear.
Methods: In this prospective cohort study, we surveyed the intake of health foods/supplements among 8,718 community health checkup participants aged 65 years and over (49.7% men; mean age, 69.3 years) and examined the association between the intake of health foods/supplements and incidence of long-term care during a 9-year follow-up period.
Results: Health foods/supplements intake was observed in 2,092 subjects (24.0%). Compared to the non-intake group, the health foods/supplements intake group showed a higher prevalence of women; a lower prevalence of smoking, alcohol consumption, comorbidities, and its medication. The most frequent health foods/supplements were vitamins, plants, and chondroitin-glucosamine/collagen. During follow-up period the incident long-term care occurred in 291 subjects (3.3%). In competing risk analysis, adjusted for confounding factors, the intake of 3 or more types of health foods/supplements was significantly associated with incidence of long-term care. The association between specific type of health foods/supplements and incidence of long-term care was not observed.
Conclusions: This study reports a high prevalence of health foods/supplements intake and the association between the intake of multiple health foods/supplements and the incidence of long-term care in the general elder population in Japan. This finding indicates that the caution is required in taking many health foods/supplements without adequate information.
Potential profiling of self-management skills in older comorbid patients
Authors: Wu Lanxin , Zhang Yan , Tian Yutong , Liu Li , Meng Lixue , Zhao Ting
Published: October 2023

Background Under the general trend of global aging, geriatric comorbidity is increasingly common andmay have some impact on the quality of life of older people. Self-management can effectively improve patient compliance and subjective initiative and improve patient quality of life. Therefore, this study's classification of older people with comorbidities through latent profile analysis could provide a reference for later personalized intervention programs for the self-management characteristics of older people with different comorbidities.
Objective Based on latentprofile analysis, we aimed to understand the categoricalcharacteristics of the self-management level of older comorbidpatients and to explore the influencing factors of the self-management level of different categories of older comorbid patients.
Method Through a cross-sectional study, 616 older comorbid patients in three districts of Zhengzhou City, Henan Province, were selected as survey subjects by using the whole cluster sampling method. The General Information Questionnaire, Chronic Disease Self-Management Scale, Health Literacy Scale, Electronic Health Literacy Scale, Collaborative Social Support Scale, and Health Empowerment Scale were used to conduct the survey.The resultsof latent profile analysis show that the self-management characteristics of older comorbid patients should be classified into 3 categories: good self-management (19.4%), moderate self-management-low lifestyle (27.9%), and low self-management (52.7%). The results of multivariate logistic regression analyses show that literacy, religiosity, health literacy, e-health literacy, appreciative social support, and health empowerment are influential factors for self-management among older comorbidpatients (P < 0.05).
Conclusion There is obvious heterogeneity in the self-management level of older comorbid patients, and it is recommended that healthcare professionals provide targeted interventions for their weaknesses according to the self-management characteristics of different categories of patients to enhance the self-management level of this population and improve their quality of life.
The combined use of erythropoietin and iron preparations for the management of postpartum anemia: a systematic review and meta-analysis
Authors: Barkovskaya Natalya A. , Shifman E. M. , Protsenko D. N.
Published: October 2023

INTRODUCTION: There are limited data on the effectiveness of erythropoietin in combination with oral ferrotherapy for the management of postpartum anemia. OBJECTIVE: To evaluate the efficacy of erythropoietin in combination with oral iron compared with oral ferrotherapy in puerperas with postpartum haemorrhage. MATERIALS AND METHODS: MEDLINE, Scopus, EBSCOhost and 5 other databases (January 1980 to February 2023) were searched for articles on the use of oral iron in combination with and without erythropoietin for the treatment of post-hemorrhagic anemia in puerperas. Primary outcomes: hemoglobin level, hemoglobin increase, hematocrit, number of blood transfusions, secondary outcomes: ferritin level, serum iron, lactation capacity. The analysis was carried out in accordance with the PRISMA guidelines, 2020. RESULTS: 4 studies were analyzed, 198 women were included. When using erythropoietin in combination with oral ferrotherapy, the cumulative value of the increase in hemoglobin concentration after 5 days, 2 weeks of treatment was significantly higher compared with the control group (mean difference [MD]: 11.83 g/L, 95% CI 4.43–19.23; р = 0.002, MD 10.13 g/L, 95% CI 4.97–15.29; р = 0.0001), respectively. The cumulative mean hemoglobin concentration after 40 days of treatment was significantly higher in the erythropoietin group (MD 11.00 g/L, 95% CI 1.70–20.30; р = 0.02). The cumulative mean hematocrit after 2 weeks of treatment was significantly higher in the erythropoietin group (MD 3.35 %, 95% CI 0.31–6.39; р = 0.03). The use of erythropoietin in combination with oral iron reduces the likelihood of blood transfusion (relative risk 0.12, 95% CI 0.02–0.95; р = 0.04). CONCLUSIONS: A faster hematological response was shown with the combined use of erythropoietin with oral ferrotherapy compared with monotherapy with iron preparations in the management of postpartum anemia. Further studies with sufficient sample sizes are required.
100 Yıllık Cumhuriyet’te Âşık Veysel’in Tarihe Düştüğü Notlar
Authors: ALİBEKİROĞLU Sertan
Published: October 2023

Toplumların varlığını ortaya koyabilmesi, yaşaması ve sürdürebilmesi için köklere sahip olması gerekmektedir. Her toplum kendini bir tarihe, coğrafyaya, ataya bağlama ihtiyacı duyar. Bu bağlanma sonucunda başta dil olmak üzere toplumu bir arada tutan kabuller, inançlar, mitler ortaya çıkar. Toplumun bu temel taşları ozanlar tarafından işlenir ve yerine konur. Kullandıkları ana malzemeler toplumun dili, kabulleri, inanmaları ve mitolojileri olduğu için ozanlara toplum inşa ediciler olarak bakmak gerekir. Canlı birer organizma olan toplumlar zaman zaman ekonomik, siyasi, askerî, doğal afetler gibi olaylar sonucu coğrafya değiştirebilir, yeniden var olmaya çalışabilirler. Yeniden yazılan tarihte ve değişebilen coğrafyada toplumu ayakta tutmak ve varlığını devam ettirebilmek için yine ozanlar devrededirler. Türkler gibi tarihî ve coğrafi derinliği çok geniş zaman ve alana yayılan milletlerin sayısız savaş, doğal afetler vb. tahrip gücü yüksek olumsuzluklara rağmen hâlâ sağlam bir şekilde ayakta durmasında ozanların büyük payı vardır. Ozanlar, toplumların geçmişlerini geleceğe aktarmakla kalmaz, aynı zamanda bugünü de tarihe yerleştirerek toplumsal tarih ve millet hafızasını geliştirir. Son dönemde toplumun hafızasını geliştiren, tarihe not düşen ozanlardan biri de Âşık Veysel’dir. Veysel, genç Cumhuriyet’in kimi siyasi olaylarını, inkılâplar ve kurumları ile içinde yaşadığı toplumun karşılaştığı doğal afetleri, hastalıkları, salgınları, iyi ve güzel olan ile acı ve çirkin olanı da şiirlerinde işleyerek topluma karşı görevlerinden biri olan tarih haznesini geliştirme görevini yerine getirmiştir. Bu çalışmada Âşık Veysel’in şiirlerinde şahit olduğu olayların neler olduğu ve bu olaylara bakış açısı verilmek hedeflenmiştir. Tespit edilen metinlerin aynı zamanda birer sözlü tarih metni olduğu varsayımıyla Âşık Veysel’in penceresinden yakın tarihle ilgili bir değerlendirme yapılması amaçlanmıştır.
Kurtuluş Savaşı’ndaki Kadın Kahramanların Cumhuriyet Dönemi’ndeki Tematik Bir Müze Bağlamında İncelenmesi
Authors: YAMAÇ ERDOĞAN Zeynep
Published: October 2023

Kurtuluş Savaşı’ndaki Millî Mücadele Dönemi, erkeklerin cephede gösterdiği üstün mücadelenin yanı sıra kadınların da elinden gelenin ötesinde, çoğu zaman erkeklerin görevlerini de paylaşarak ve üstlenerek büyük bir kahramanlık sergiledikleri bir dönem olmuştur. Bu dönemde Halide Edip Adıvar başta olmak üzere, Kara Fatma ve daha birçok kadın kahraman verdikleri bağımsızlık mücadelesiyle Cumhuriyet’in temellerinin atılmasında da önemli role sahip olmuştur. Bu çalışmada, Kurtuluş Savaşı’ndaki kadın kahramanlar hakkında çeşitli bilgilere yer verilerek Ankara’da tematik bir müze olarak açılan Halide Edip Adıvar ve Kadın Kahramanlar Müzesi yerinde incenmiş ve ziyaretçilerin müze deneyimiyle ilgili yorumları nitel analiz programı ATLAS.ti aracılığıyla analiz edilmiştir. Araştırmadan elde edilen sonuçlara göre; müze tarihe ışık tutmasıyla millî bilinci pekiştirerek Millî Mücadele Dönemi’nin anlaşılmasına katkı sunmaktadır. Bununla birlikte, ziyaretçilerin müzede yaşadıkları turizm deneyiminden memnun oldukları, müzede millî duygular yaşadıkları anlaşılmıştır. Tematik bir müze olarak kurulmuş olan Halide Edip Adıvar ve Kadın Kahramanlar Müzesi’nin, Sakarya Meydan Muharebesi Tarihî Millî Parkı içerisinde yer almasının önemli bir avantaj olduğu düşünülmektedir. Müzenin içeriğinde yer alan canlandırmalar, maketler, ses sistemi, izletilen belgeseller de görsel açıdan ziyaretçilerin deneyiminin kalitesinin artmasına ve gerçeklik duygusuyla adeta zamanda bir yolculuk yaparak çeşitli duygular hissetmesine hizmet etmektedir. Kurtuluş Savaşı’nda yaşanılan zulme karşı özgürlük mücadelesi vermede ve vatanı düşman işgalinden kurtarmada halk, büyük fedakârlıklar göstermiştir. Bu fedakârlıkların içselleştirilmesinde ve kadınların Millî Mücadele’deki rolünün anlaşılmasında Halide Edip Adıvar ve Kadın Kahramanlar Müzesi ağırlıklı bir konumda bulunarak Türk kadınını da onurlandırmaktadır.
Türkiye Cumhuriyeti Devletimizin Kurucu Temel İlkesi: Milliyetçilik
Authors: ÇETİN Nurullah
Published: October 2023

23 Nisan 1920’de fiilen ve resmen kurulan, 29 Ekim 1923 tarihinde de rejiminin adı Cumhuriyet olarak belirlenen devletimizin altı temel kurucu ilkesi olmakla birlikte bunlar arasında en önde geleni milliyetçiliktir. Milliyetçilik diğer beş ilkenin de ana kaynağıdır. Milliyetçilikten kasıt Türk milliyetçiliğidir. Dolayısıyla milliyetçilik kapsayıcı ve kuşatıcı bir ilkedir. Atatürk Türkiye Cumhuriyeti Devleti’ni bağımsız, millî bir Türk devleti olarak kurdu. Türk vatanını bölünmez tek Türk vatanı olarak tanımladı. Devletimizi temsil eden tek marşın İstiklal Marşı olduğunu Meclis kararıyla kayda geçirdi. Türk dili olan Türkçeyi tek resmî dil olarak belirledi. Devletimizi temsil eden tek bayrağın Türk bayrağı olduğunu ilan etti. Devletimizin bölünüp parçalanamaz tek Türk devleti olduğunu ısrarla vurguladı. Milletimizin adının sadece Türk milleti olduğunu perçinledi. Etnik kökenlerine bakmadan bütün vatandaşlarımızı Türk milleti çatısı altında topladı. Türk tarihini bir bütün olarak ortaya koydu. Müzik, resim, mimarlık, tiyatro, edebiyat gibi sanatın bütün türlerinde Türk millî ruhunun damgasını vurdu. Dış politikada Türk milletinin menfaatlerini tek belirleyici yaptı. Cumhuriyetimizin en önemli kazanımlarından biri, Türk milletine kendi millî kültürünü tanıtması, koruması, yaşatması, öğretmesi ve geliştirmesi olmuştur. Zira millet, kendine özgü kültürü olan topluluk demektir. Türk milleti de dünyanın en eski kültürüne sahip bir millettir. Biz millet olarak var olacaksak, bu ancak bizi diğer milletlerden ayıran, bize özgü millî kültürümüzü korumamıza ve yaşatmamıza bağlıdır. Bu çerçevede Atatürk, millî kültürün değerini kavramış ve yeni kurduğu devletin temeline Türk millî kültürünü koymuştur.
REPRESENTASI KOMODIFIKASI AGAMA PADA IKLAN WEBSERIES MIRACLE OF HIJRAH OLEH PRIMALAND
Authors: Ma'rufah Hafidhoh
Published: October 2023

Developments in technology and information bring changes to the pattern of product marketing. Marketing advertisements undergo various transformations, from print advertisements to ads in the form of videos, from short videos to videos in the form of web series. In its development, too, sharia-based products are increasingly familiar to the public. One form of Sharia product is Sharia-based housing. This residence offers religious facilities such as a prayer room and an archery field. In addition, Sharia housing also uses non-usury payments using an in-house scheme. It is undeniable that the commodification of religion accompanies the advertisements being promoted. Through residential advertisements in the form of web series, Primaland markets its various Sharia residential products. Various commodifications of faith are found in this advertisement. Three forms of commodification were found: Islamic iconography (description of identity), the use of figures with Muslim influencer backgrounds, and the existence of advertising texts or religious messages conveyed through dialogues in web series.
Demonstration of real-time monitoring in smart graded-water supply grid: an institutional case study
Authors: Singh Shobhana , Choudhary Manoj , Sørensen Kim
Published: October 2023

Real-time information on water supply and quality is a crucial asset for planning and managing water resources, infrastructure, and scientific research for sustainable development.  In this direction, the innovative concept of smart water infrastructure is progressing. The present paper reports a case study on the demonstration of a `smart graded-water supply grid' on the campus of the Indian Institute of Technology Jodhpur, India. The paper describes the transformation of ∼13 km long water distribution network that supplies drinking water to ∼5,000 inhabitants into smart supply grid by deploying sensors and establishing an IoT-enabled real-time monitoring platform. The data sets of water flow and pressure collected from sensor nodes are analyzed to understand the characteristic diurnal water usage profiles unique to student hostels on the campus. The data show a distinctive consumption profile of student hostels over the weekdays with a maximum peak consumption of 16.38 m3/h. Monitoring of vital quality parameters such as chlorine, pH, and temperature demonstrate acceptable levels thereby ensuring compliance with safety standards. The purpose of the paper is to provide insights from a real-world case and close the knowledge gap between general awareness and the potential of smart water grid in sustainable management of graded-water services.
O gesto de levantar a mão: um olhar sob a perspectiva do contínuo de Kendon
Authors: Oliveira da Silva Eriglauber Edivirgens , Cavalcante Marianne Carvalho Bezerra , Holanda Driely Xavier de
Published: October 2023

O gesto de levantar a mão é uma produção gestual tão comum nas interações com múltiplos interlocutores para pedir o turno de fala, que foi traduzido como um botão em plataformas de interação online com múltiplos participantes, evidenciando a importância da sua função para esse contexto. Diante disso, o presente estudo busca de forma geral analisar os aspectos linguísticos que envolvem o gesto de levantar a mão, objetivando de forma específica debater teoricamente sobre o gesto de levantar a mão no contexto de sala de aula e classificar as ocorrências desse gesto sob a perspectiva do Contínuo de Kendon (MCNEILL, 2000). Metodologicamente, o estudo se compreende como uma pesquisa descritiva e exploratória de caráter qualitativo interpretativista, organizando os passos da investigação da seguinte forma: 1) levantamento bibliográfico, para o desenvolvimento do debate teórico;  2) seleção e transcrição dos dados, para o desenvolvimento de uma análise classificatória com dados reais e; 3) análise de dados, momento em que a teoria e os dados se encontram. Como embasamento teórico, o atual estudo usufrui de autores que defendem o conceito de matriz gesto-fala (MCNEILL, 1985; MCNEILL, 2000; MCNEILL, 2006; BARROS; CAVALCANTE, 2015; CAVALCANTE, 2019) e autores que investigam o processo interativo professor-aluno no contexto de sala de aula (MARCUSCHI, 2008; SILVA, 2008; SILVA, 2010; DIXON; EGENDOERFER; CLEMENTS, 2009; BÖHEIM et al., 2020). Como resultado, a investigação consegue evidenciar teoricamente que o gesto de levantar a mão pode ser um importante recurso para a manutenção dos turnos de fala em contexto de sala de aula e, durante a análise do gesto sob a perspectiva do Contínuo de Kendon, ficou claro que o gesto de levantar a mão se trata de um emblema gestual.
A Study on Lee Kyu-gyeong(李圭景)'s 『Oju-Pilju(五洲筆疇)』: In addition to introducing a newly discovered book
Authors:   The Association of DaeDong-Hanmun, Kim Bo-sung
Published: October 2023

『Oju-Yeonmunjangjeon-Sango(五洲衍文長箋散稿)』 by Lee Kyu-gyeong (李圭景, 1788~1856) is an encyclopedia of Joseon in the 19th century. It is highly evaluated for not only having a lot of content, but also for making good use of previous books. A symposium with the theme of 『Ohjuyeonmunjangjeonsango』 was held, and at this time Lee Kyu-gyeong's erudition was revealed and the level of Korean intellectual history in the 19th century was proved.
Lee Kyu-gyeong's 『Shiga-Jumdeung(詩家點燈)』 is a book that criticizes Korean and Chinese poetry and sentences. Researchers do not use it as much as 『Oju-Yeonmunjangjeon-Sango』 because it is difficult to identify characters and it is not databased, but there is no disagreement that it has a lot of content like 『Oju-Yeonmunjangjeon-Sango』. 『Oju-Yeonmunjangjeon-Sango』 and 『Shiga-Jumdeung』 make us look forward to the value of another of Lee Kyu-kyung's books that have not been discovered yet.
『Oju-Yeonmunjangjeon-Sango』 says “It can be seen in detail in 『Oju- Pilju(五洲筆疇)』”, so 『Oju-Pilju』, which was obviously Lee Kyu-kyung's book but had not been seen before, was newly discovered. It is a hand-held book [袖珍本] similar in size to 『Shiga-Jumdeung』. There are 20 letters in 10 lines and a total of 72 pages. The condition of the book is very good, so it is easy to distinguish the letters.
『Oju-Pilju』 contains military operations, which are the core of war, walls for defense, pavilions to watch military camps, armor and weapons, carts carrying munitions, other things that could be weapons, military medicine, and amulets to defeat the enemy. In other words, it is a ‘book on military strategy(兵法書)’ with quite a bit of content. Through two prefaces written by Lee Kyu-gyeong, he emphasized that as a Confucian scholar, the purpose of separately writing the book on military strategy, 『Oju-Pilju』, was to achieve a peaceful era.
Looking at the parts related to the walls, weapons, and carts that Lee Kyu-kyung said he put effort into in the preface, it is clear that he had a high level of knowledge about ‘strategy’. Through the review of 『Oju-Pilju』, it is possible to accurately grasp the level of Joseon books on military strategy in the 19th century.
Four Decades of Newborn Screening: A Historical Perspective of Laboratory Practices
Authors: Alonso-Fernández José Ramón
Published: October 2023

The personal experience of 36 years in charge of the Newborn Screening Laboratory in Galicia and the consequences of the recent advancement of sampling from 3 days to 24 hours of the newborn's life are reviewed. The implication in the results of the assay of reducers in urine with the Mandelin reagent and its alternatives is commented. The implication in the effects of TSH in blood and the possible ways of dealing with the situation. Since 1978, the Newborn Screening Program in Galicia has maintained the urine sample on paper (Berry-Woolf specimen) and blood on paper (Guthrie specimen), so the possibilities of the urine sample are discussed, which are not being taken advantage of. The ignorance of LI Woolf's time at GOSH, where what brought us here was gestated, and his recommendations for preparing the diet, to which due attention was not paid. The contributions of the in vitro diagnostic industry, the concepts associated with Clinical Chemistry, and its professionals' work are discussed.KeywordNewborn screening; urine sample on paper; LI Woolf; in vitro diagnostic industry
Effect of shading and fertilization with iron and sulfur on some vegetative
growth and leaves mineral content of Gardenia jasminoides Ellis.
Authors: Hussein Ali J , SH. Ahmed Mahmood.
Published: October 2023

This study was conducted in a glass house, Dept of Hort. and Landscape, College
of Agriculture, Univ. Anbar, during the 2021-2022 growing season, to investigate
the influence of shading and fertilization on the growth and leaf mineral content
of gardenia plants. This study included two factors: two levels of shading at 0
(S0), shading 50 % (S1) and four treatments of fertilizations, control (F0), chelated
iron spray at 2 ml.L-1
(F1), addition of magnesium sulfate to pots at 7 gm.plant-1
(F2) and chelated iron spray at 2 ml.L-1 + addition of magnesium sulfate to pots at
7 gm.plant-1
(F3) and their interaction. Treatments were replicated three times at
Split plots design (Shading is the main plot) in an RCBD. The number of plants
used was 36 plants. The results showed that interaction treatment (S1F3) significantly increased the plant height by 6.517 cm, the highest increase in shoot length
of 11.267 cm, and the number of 94.107 leaves.plant-1
, highest leaf area of
9437.463 cm2
, highest leaf nitrogen content of 1.877 % and highest leaf potassium content of 0.561 %, while lower values of these traits were in interaction
treatment (S0F0).
Keywords: iron, sulfur, vegetative growth, Gardenia jasminoides Ellis
Effect of parasite infection on IgE, Anti-TG, Anti-TPO of thyroiditis patients
Authors: Ghassan Saeid Yasamin , Taher Mohammed Sabaa , Qasim Ali Luma
Published: October 2023

This study was conducted to investigate parasitic infection's effect on the thyroid
gland's functions by hypo- or hyperthyroidism and inflammation by measuring
some physiological and immunological indicators. 130 blood and stool samples
were collected from both genders, including 80 samples from people with thyroid
disorders and 50 samples from healthy people. Anti-TG, anti-TPO and IgE were
estimated by using the Cobas e411 device. The general stool examination was
carried out to confirm the presence of a parasitic infection and determine the type
of parasites. The type of parasites found the most affected were Entamoeba histolytica, Giardia lamblia, Blastocystis hominis, and the last parasite, Cryptosporidium. Anti-TG, anti-TPO, and IgE immunoassays significantly increased hypo
and hyperthyroidism cases compared to the control. The increase was higher in
parasitic-infected patients than in non-infected patients compared to the control.
Results of the infected were as follows: (94.41, 27.96, 361.44) IU/ml and (54.13,
18.48, 308.18) IU/ml, for non-infected (55.46, 18.48, 149.67) IU/ml and (89.56,
20.80, 90.67) IU/ml. Compared to the control (22.3, 7.05, 62.93) IU/ml, respectively. Conclusion: This study showed that infection with a parasite affected the
performance of the thyroid gland.
Keywords: Parasites; Thyroid Disorders; Anti-TG; Anti-TPO; IgE.
A comparative study between COVID-19 vaccine (Pfizer and Sinopharm) and their relationship to some cytokines
Authors: Shaheed Tuama Baidaa , Murad Al-Rubaye Abeer Fauzi , Merza Amal
Published: October 2023

The research was carried out in Babylon Governorate between 12/10/2021 and 27/12/2022 on 85 vaccinated individuals with or without prior infection as a test group, in comparison to 35 individuals recovering from COVID-19, which was mentioned as a positive (+ve) control, and with 30 individuals from a healthy population (non-infected with Covid-19), as a negative (-ve) control groups. Various parameters were studied to evaluate immunological status. The research aimed to evaluate the immune aspects of people vaccinated with the coronavirus vaccine. The study revealed statistically significant variations in the vaccine efficiency for the two investigated vaccinations between the periods following vaccination. Besides, the Pfizer vaccine induces more protection than Cinopharm at the cellular and humeral immune reactivity. Keywords: Vaccine; Cinopharm; Pfizer; Cytokines.
Evaluation of the effect of different toothpastes on the frictional resistance of aesthetic archwires: an in vitro study
Authors: Ali Mohammed Zekri Hussein , Issa Saleem Alan , Basim Mahmood Abeer , Hamid Obaid Dina
Published: October 2023

there has been a trend for using aesthetic orthodontic treatment by many patients
recently. The aim of this study was to evaluate the brushing effect of three brands
of toothpaste on the frictional resistance of two brands of aesthetic archwires (in
wet conditions). in this study, two brands of fully coated aesthetic archwires,
Teflon-coated and Epoxy-coated archwires, were utilized in the study. Forty
segments from the straight ends of each archwire were cut (total of 80 wires), inserted into ceramic brackets and ligated with the conventional figure "O" elastomeric ligatures (bonded on CNC blocks). Every ten pieces for each type of aesthetic archwire were brushed for one minute daily for thirty days with three types
of toothpaste (Ortho. Kin, GUMOrtho and LACALUT White & Repair) and distilled water (except ten pieces for each type of aesthetic archwire were brushed
only with distilled water and without toothpaste). These CNC blocks were tested
using an Instron Tinius Olsen machine with distilled water. The tests used for
statistical analysis were an Independent t-test and an ANOVA test at a 0.05 level
of significance. The study showed no significant difference in static and kinetic
frictional resistance between the coated archwire and the kinds of toothpaste. The
orthodontists can use either Epoxy or Teflon-coated archwires for patients undergoing orthodontic treatment (working stage) who are using either type of
toothpaste (Ortho. Kin, GUMOrtho or LACALUT White & Repair) for maintenance of oral hygiene.
Keywords: Aesthetic archwires, Friction, Toothpaste
Oral hygiene and salivary IgA in relation to gingival condition in
pregnant women
Authors: Hussein Saja Ali , Alwaheb Athraa
Published: October 2023

Pregnancy is a physiological state that causes changes in many parts of the body,
including the oral cavity. Gingivitis has been reported to be the most common oral
manifestation during pregnancy, most likely due to an exaggerated inflammatory
response to the dental plaque. This study aims to investigate oral hygiene and
salivary IgA concerning gingival conditions in pregnant women. In this study, the
total sample included was 80 women. The study group consisted of 40 pregnant
women: 20 females in the first and 20 in the third trimester, while the control group
included 40 non-pregnant women. Between 9 and 11 a.m., unstimulated saliva was
collected. The rate of salivary flow and concentration of salivary immunoglobulin
A were measured. Dental plaque, calculus and gingivitis were assessed. Results
demonstrated that plaque, calculus and gingival indices were higher in a pregnant
group, with significant differences in plaque index only. In contrast, salivary flow
rate was lower in pregnant women with no significant difference. Salivary IgA was
the highest level in the pregnant group during the third trimester, with no statistical
difference. In conclusion, the pregnant women revealed a poor oral hygiene status
and alteration in salivary parameters, leading to an increased prevalence of gingivitis in pregnant women.
Keywords: Gingivitis, salivary flow rate, Pregnant women, Salivary IgA.
AI Algorithm to Predict Acute Coronary Syndrome in Prehospital Cardiac Care: Retrospective Cohort Study
Authors: de Koning Enrico , van der Haas Yvette , Saguna Saguna , Stoop Esmee , Bosch Jan , Beeres Saskia , Schalij Martin , Boogers Mark
Published: October 2023

Background

Overcrowding of hospitals and emergency departments (EDs) is a growing problem. However, not all ED consultations are necessary. For example, 80% of patients in the ED with chest pain do not have an acute coronary syndrome (ACS). Artificial intelligence (AI) is useful in analyzing (medical) data, and might aid health care workers in prehospital clinical decision-making before patients are presented to the hospital.

Objective

The aim of this study was to develop an AI model which would be able to predict ACS before patients visit the ED. The model retrospectively analyzed prehospital data acquired by emergency medical services' nurse paramedics.

Methods

Patients presenting to the emergency medical services with symptoms suggestive of ACS between September 2018 and September 2020 were included. An AI model using a supervised text classification algorithm was developed to analyze data. Data were analyzed for all 7458 patients (mean 68, SD 15 years, 54% men). Specificity, sensitivity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for control and intervention groups. At first, a machine learning (ML) algorithm (or model) was chosen; afterward, the features needed were selected and then the model was tested and improved using iterative evaluation and in a further step through hyperparameter tuning. Finally, a method was selected to explain the final AI model.

Results

The AI model had a specificity of 11% and a sensitivity of 99.5% whereas usual care had a specificity of 1% and a sensitivity of 99.5%. The PPV of the AI model was 15% and the NPV was 99%. The PPV of usual care was 13% and the NPV was 94%.

Conclusions

The AI model was able to predict ACS based on retrospective data from the prehospital setting. It led to an increase in specificity (from 1% to 11%) and NPV (from 94% to 99%) when compared to usual care, with a similar sensitivity. Due to the retrospective nature of this study and the singular focus on ACS it should be seen as a proof-of-concept. Other (possibly life-threatening) diagnoses were not analyzed. Future prospective validation is necessary before implementation.
The role of leptin resistance in the development of thyroid neoplasia
Authors: Miroshnichenko O.S.
Published: October 2023

Background. Leptin influences energy metabolism, as it is able to inform the central nervous system about adipose tissue reserves, and is also an important neuroendocrine regulator. Therefore, an increase in leptin stimulates thyrotropin-releasing hormone secretion, which leads to an increase of thyroid-stimula­ting hormone with normal or slightly elevated levels of thyroxine and triiodothyronine. Leptin imbalance leads to leptin resistance, which develops as a result of impaired sensitivity of hypothalamic receptors to leptin, its penetration through the blood-brain barrier, damage or dysfunction of these receptors, dysfunction of transport proteins accompanied by an increased content of inflammatory mediators that affect leptin receptors and, in turn, damage them. The purpose of the study was to reveal the relationship between hyperleptinemia and leptin resistance in people with different body weight and thyroid nodules. Materials and methods. One hundred and twenty-three patients were examined, who were divided into four groups depen­ding on the body mass index to determine the le­vels of leptin, insulin, and degree of insulin resistance: group 1 — excess body weight (n = 22); group 2 — class 1 obesity (n = 28); group 3 — class 2 obesity (n = 32); group 4 — class 3 obesity (n = 21). The control group consisted of persons with normal body weight (n = 20). Results. It was found that all examined patients had hyperleptinemia (34.5 ng/ml) simultaneously with hyperinsulinemia and insulin resistance (HOMA-IR was 8.3 units). Patients with thyroid neoplasia compared to individuals with normal body weight had significantly higher (by 1.3 times) serum leptin concentrations (p < 0.05; p < 0.001). The research proved that the level of leptine­mia is directly related to the body mass index, waist circumference (r = 0.54; p < 0.001) and hip circumference (r = 0.51; p < 0.001). Conclusions. Among patients with leptin resistance and insulin resistance against the background of obesity of various classes, thyroid neoplasms occur in 28 % of cases. Leptin resistance along with insulin resistance can be considered as independent risk factor for neoplasia. People with abdominal obesity need a mandatory exami­nation of the structural and functional state of the thyroid gland for early detection of nodular neoplasms.
A rare case of medullary carcinoma
Authors: Lishchuk O.Z. , Suslyk Н.I. , Urbanovych A.M.
Published: October 2023

Medullary thyroid cancer (MTC) accounts for 5–10 % of all thyroid cancers. Most cases (75 %) are sporadic, but the proportion of patients with MTC and a familial predisposition syndrome is the highest among those with any hereditary cancer syndrome (about 25 %), and this possibility should be considered when examining a patient with MTC. Familial syndromes include multiple endocrine neoplasia (MEN) 2A, MEN 2B, and non-MEN familial MTC (familial MTC). Familial MTC syndromes occur in approximately one case per 30,000 of the population. Reduced penetrance and clinical variability are well-established features of many monogenic disorders, particularly phenotypes associated with the RET proto-oncogene. They require an individual assessment of the pathogenic effects and clinical significance of any identified new sequence of the RET va­riant as prerequisites for individual genetic counseling and planning of medical monitoring and treatment. Diagnostic criteria for the disease have been outlined, molecular and genetic aspects have been discussed, and the determination of treatment and further observation has been addressed. The article describes a clinical case of a rare variant of MTC. Treatment of this pathology with radical extrafascial thyroidectomy is under consideration. Given the ineffectiveness of radioiodine and chemotherapy, the main task in the treatment of MTC is early diagnosis, radical surgical intervention, and active monitoring aimed at early detection of disease recurrence. When planning prophylactic thyroidectomy, it is recommended to focus on the stratification of the level of RET gene mutations and the timing of prophylactic thyroidectomy proposed by the American Thyroid Association. The introduction of molecular genetic research into clinical practice for the purpose of diagnosing MTC allows for the objective assessment of the genetic lineage of the disease within a biological family. A timely diagnosis of MTC makes it possible to prescribe an adequate treatment at the stage of preclinical manifestations of the disease, which can significantly increase the quality and duration of life.
Review of the monograph “Food, nutrition, and human diseases. Evolutionary and historical aspects” (author — H.F. Hendeleka, MD, PhD, Professor; Odesa: Polygraph, 2023. 496 p.)
Authors: Authors No
Published: October 2023

No abstract
The Role of Emotional States on Purchase Decision-Making among Novice Stock Investors
Authors: Dardana Joshua Antonius , Elgeka Honey Wahyuni Sugiharto
Published: October 2023

Novice stock investors tend to make investment decisions based on their emotions, so they usually have lower performance. Emotions can affect decision-making through immediate emotions (emotional states) and expected emotions (emotional consequences). Happy and sad are the strongest emotions. Therefore, this research aims to examine and explain the effect of emotional states, specifically happy and sad, on novice stock investors' purchase decision-making. This research uses the experiment method, with 30 novice stock investors divided into three groups (two experimental and one control group). The result shows no effect between happy and sad emotional states on purchase decision-making (p > 0,05). The result is caused by participants' tendencies to make rational decisions for the highest utility. The higher the utility they get, the happier they will be, and vice versa. Thus, happy and sad emotions act as expected emotions, not as immediate emotions in decision-making.
Efek Penggunaan Emoji pada Kefasihan Pemrosesan dalam Bersosial Media: Studi Eksperimental
Authors: Salsabila Ghina , Aisy Bthari Salsabiela Rohadatul , Salsabila Rias Rana , Febriani Wury Utami , Hafisah Lia  Nur , Shadiqi Muhammad Abdan
Published: October 2023

Emoji sering digunakan untuk menunjukkan emosi saat berkomunikasi di media sosial, sehingga diperlukan kefasihan pemrosesan untuk memahami dan mempercayai isi pesan secara baik. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan penggunaan emoji terhadap kefasihan pemrosesan. Partisipan penelitian adalah mahasiswa aktif Fakultas Kedokteran Universitas Lambung Mangkurat angkatan 2017-2020 yang menggunakan media sosial Twitter, dan berusia lebih dari 17 tahun sebanyak 61 orang. Penelitian ini merupakan eksperimen replikasi dengan desain between subjek yang dilakukan pada dua kelompok eksperimen yaitu kelompok perlakuan kongruen (pemberian emoji yang sesuai makna teks) dan inkongruen (pemberian emoji yang tidak sesuai makna teks). Hasil independent sample t-test menunjukkan bahwa tidak terdapat perbedaan yang signifikan pada kefasihan pemrosesan antara kedua kelompok perlakuan. Hal ini berarti bahwa tidak ada efek penggunaan emoji terhadap kefasihan pemrosesan.
Exploring and Construction On Practicality Instruction System in Engineering Education Based On CDIO Concept
Authors: Yang Zhaohui , Zhou Haixia
Published: October 2023

Choosing a faculty of the college as an attempt, the author analyzed the CDIO concept and its necessity in practicality instruction system, discussed the construction of practicality instruction system in engineering education under the direct of CDIO concept.
Essential Oil from Extraction of Pepper Leaves (Piper Nigrum L.) using Microwaves
Authors: Patmawati Yuli , Karim Khairuddin
Published: October 2023

Pepper plants are a commodity with high economic value. However, the problem is that pepper leaves are not widely used. When pruning for rejuvenation, 75% of pepper leaves are just thrown away. To overcome this problem, it is necessary to use and process pepper leaves into essential of pepper oil. One method of extracting essential pepper oil is a microwave-assisted extraction process. The aim of this research was to investigate the effect of extraction time on the yield of essential oil derived from pepper leaves. Pepper leaves that are wilted for 7 days are chopped to ± 1-2 cm, carry out extraction using a microwave using 200 ml water as a solvent, for 60, 90, 120, 150, 180 and 210 minutes. The research results showed that the optimum yield of essential pepper oil was obtained of 0.5937% at 180 minutes extraction process. The characteristic of essential oil derived from pepper leaves were obtained: a specific gravity of 0.8710, a refractive index of 1.4873 and an acid number of 0.3809 mg KOH/g.
Biogenic Materials and Wastes: A Sustainable Source of Clean Energy
Authors: Pandey Rahul , Verma Amit Kumar , Yadav Amarjeet , Yadav Pramod
Published: October 2023

Abstract: Progress in agriculture and industry is taken as a general criterion for the development of any country, and this craze has resulted in unlimited exploitation of every bit of natural resources. The exploitation of natural resources includes biological and nonbiological waste. Wastes that are produced due to the exploitation of biological materials such as agro waste, rice husk, coconut shell, jatropha oil, banana peels, tea-tree extract, waste food, food products, insects, and chicken fat are known as biogenic waste. Biogenic materials can be used to minimize the environmental hazards produced through the exploitation of different nonbiogenic materials that are used by a larger number of populations in their daily life. Thus, biogenic materials can be used for the sustainable development of clean energy, as their production does not require industrialization. Currently, different types of biological materials are used in different sectors ranging from the construction sector to pharmaceuticals as well as food, biorefineries and agriculture. These materials, on the one hand, are proven to be very useful, as they have fulfilled the requirements with the goal of less environmental hazards in their production; they also have a dark phase with negative environmental impacts after their use. Modern research has led to the use of biogenic waste by transforming it into different types of nanomaterials that can be reused with minimum pollution and can be commercialized. This chapter includes different types of biomaterials and their uses along with biogenic wastes. The final section includes different types of transforming products of biogenic waste to nanomaterials along with their uses.
Leveraging Smart Contracts for Decentralized Healthcare Data Sharing
Authors: Shevtekar Prof. Sumit S. , Chaudhari Sanket
Published: October 2023

Abstract: Healthcare data sharing is essential for enhancing healthcare service quality and efficiency. However, traditional healthcare data sharing systems are often centralized, opaque, and inefficient. This can pose security and privacy concerns, as well as delays and errors in data access. The integration of blockchain-based smart contracts into the healthcare sector has introduced a transformative paradigm for decentralized healthcare data sharing. This research paper explores the multifaceted landscape of leveraging smart contracts to enhance the security, efficiency, and accessibility of healthcare data sharing. By offering secure, transparent, and automated mechanisms, smart contracts address critical challenges in patient data management, consent verification, and interoperability across healthcare systems.
Pengaruh kepribadian neuroticism dan extraversion terhadap fear of missing out pada remaja
Authors: Ramadhani Rivaldi Izza , Suryaningrum Cahyaning
Published: October 2023

Teenagers is individuals who are vulnerable to experiencing FoMO or fear of missing out. FoMO is a person’s concern about missing moment or activity with the people closest to them. Neuroticism and extraversion is the personality dimensions of the big five personality that can influence adolescents in experiencing FoMO. The purpose this study was to determine the effect neuroticism and extraversion personality on FoMO in adolescents and see which influence is greater between neuroticism and extraversion personality. Instruments used FoMO Scale and BFI. The results of the analysis using multiple linear regression show the probability (p=0.00) indicates that neuroticism and extraversion personality have an influence on FoMO in adolescents. The probability on the neuroticism variable (p=0.00) with a standardized value (β=0.41), while on the extraversion variable (p=0.04) with standardized value (β=0.17), the neuroticism variable has greater influence on the fear of missing out in adolescents than the extraversion variable.Keywords: Adolescent, extraversion, fear of missing out, neuroticism