bluuebunny/crossref_metadata_2025 huggingface dataset:
BBUNS: Bluetooth Beacon-Based Underground Navigation System to Support Mine Haulage Operations
Authors: Baek Jieun , Choi Yosoon , Lee Chaeyoung , Suh Jangwon , Lee Sangho
Published: November 2017

A Bluetooth beacon-based underground navigation system (BBUNS) was developed to identify the optimal haul road in an underground mine, track the locations of dump trucks, and display this information on mobile devices. A three-dimensional (3-D) geographic information system (GIS) database of the haul roads in an underground mine was constructed, and the travel time for each section was calculated. A GIS database was also constructed for 50 Bluetooth beacons that were installed along the haul roads. An Android-based BBUNS application was developed to visualize the current location of each dump truck and the optimal haul road to the destination on mobile devices, using the Bluetooth beacon system that was installed in the underground mine. Whenever the BBUNS recognized all of the Bluetooth beacons installed in the underground mine, it could provide the dump truck drivers with information on the current location and the two-dimensional (2-D) and 3-D haul road properties. The operating time of each dump truck and the time spent on each unit task could be analyzed using recorded data on the times when Bluetooth beacon signals were recognized by the BBUNS. The underground mine navigation system that was developed in this study can contribute to the improvement of haul operation efficiency and productivity.
Optimization of Goat Milk with ACE Inhibitory Peptides Fermented by Lactobacillus bulgaricus LB6 Using Response Surface Methodology
Authors: Shu Guowei , Shi Xiaoyu , Chen He , Ji Zhe , Meng Jiangpeng
Published: November 2017

In the present study, the incubation conditions of goat milk fermented by Lactobacillus bulgaricus LB6 were optimized to increase the angiotensin converting enzyme (ACE, EC 3.4.15.1) inhibitory activity by Box–Behnken design of response surface methodology. Incubation temperature, whey powder, and calcium lactate had significant effects on ACE inhibition rate and viable counts of LB6 during incubation. The results showed that optimal conditions of fermentation were found to be 37.05 °C, 0.8% (w/w) whey powder and 0.50% (w/w) calcium lactate. ACE inhibition rate increased significantly from 71.04 ± 0.37% to 83.31 ± 0.45% and the viable counts of Lactobacillus bulgaricus LB6 reached to 8.03 × 107 cfu·mL−1 under the optimal conditions, which approached the predicted values 83.25% and 8.04 × 107 cfu·mL−1. The optimal fermentation conditions can be a good reference for preparing ACE inhibitory peptides from goat milk.
The Complete Chloroplast Genome Sequences of Aconitum pseudolaeve and Aconitum longecassidatum, and Development of Molecular Markers for Distinguishing Species in the Aconitum Subgenus Lycoctonum
Authors: Park Inkyu , Yang Sungyu , Choi Goya , Kim Wook , Moon Byeong
Published: November 2017

Aconitum pseudolaeve Nakai and Aconitum longecassidatum Nakai, which belong to the Aconitum subgenus Lycoctonum, are distributed in East Asia and Korea. Aconitum species are used in herbal medicine and contain highly toxic components, including aconitine. A. pseudolaeve, an endemic species of Korea, is a commercially valuable material that has been used in the manufacture of cosmetics and perfumes. Although Aconitum species are important plant resources, they have not been extensively studied, and genomic information is limited. Within the subgenus Lycoctonum, which includes A. pseudolaeve and A. longecassidatum, a complete chloroplast (CP) genome is available for only one species, Aconitum barbatum Patrin ex Pers. Therefore, we sequenced the complete CP genomes of two Aconitum species, A. pseudolaeve and A. longecassidatum, which are 155,628 and 155,524 bp in length, respectively. Both genomes have a quadripartite structure consisting of a pair of inverted repeated regions (51,854 and 52,108 bp, respectively) separated by large single-copy (86,683 and 86,466 bp) and small single-copy (17,091 and 16,950 bp) regions similar to those in other Aconitum CP genomes. Both CP genomes consist of 112 unique genes, 78 protein-coding genes, 4 ribosomal RNA (rRNA) genes, and 30 transfer RNA (tRNA) genes. We identified 268 and 277 simple sequence repeats (SSRs) in A. pseudolaeve and A. longecassidatum, respectively. We also identified potential 36 species-specific SSRs, 53 indels, and 62 single-nucleotide polymorphisms (SNPs) between the two CP genomes. Furthermore, a comparison of the three Aconitum CP genomes from the subgenus Lycoctonum revealed highly divergent regions, including trnK-trnQ, ycf1-ndhF, and ycf4-cemA. Based on this finding, we developed indel markers using indel sequences in trnK-trnQ and ycf1-ndhF. A. pseudolaeve, A. longecassidatum, and A. barbatum could be clearly distinguished using the novel indel markers AcoTT (Aconitum trnK-trnQ) and AcoYN (Aconitum ycf1-ndhF). These two new complete CP genomes provide useful genomic information for species identification and evolutionary studies of the Aconitum subgenus Lycoctonum.
How Secondary and Tertiary Amide Moieties are Molecular Stations for Dibenzo-24-crown-8 in [2]Rotaxane Molecular Shuttles?
Authors: Riss-Yaw Benjamin , Morin Justine , Clavel Caroline , Coutrot Frédéric
Published: November 2017

Interlocked molecular machines like [2]rotaxanes are intriguing aesthetic molecules. The control of the localization of the macrocycle, which surrounds a molecular axle, along the thread leads to translational isomers of very different properties. Although many moieties have been used as sites of interactions for crown ethers, the very straightforwardly obtained amide motif has more rarely been envisaged as molecular station. In this article, we report the use of secondary and tertiary amide moieties as efficient secondary molecular station in pH-sensitive molecular shuttles. Depending on the N-substitution of the amide station, and on deprotonation or deprotonation-carbamoylation, the actuation of the molecular machinery differs accordingly to very distinct interactions between the axle and the DB24C8.
The Protective Effects of Astaxanthin on the OVA-Induced Asthma Mice Model
Authors: Hwang Yun-Ho , Hong Seong-Gyeol , Mun Seul-Ki , Kim Su-Jin , Lee Sung-Ju , Kim Jong-Jin , Kang Kyung-Yun , Yee Sung-Tae
Published: November 2017

Although astaxanthin has a variety of biological activities such as anti-oxidant effects, inhibitory effects on skin deterioration and anti-inflammatory effects, its effect on asthma has not been studied. In this paper, the inhibitory effect of astaxanthin on airway inflammation in a mouse model of ovalbumin (OVA)-induced asthma was investigated. We evaluated the number of total cells, Th1/2 mediated inflammatory cytokines in bronchoalveolar lavage fluid (BALF) and airway hyperresponsiveness as well as histological structure. The level of total IgE, IgG1, IgG2a, OVA-specific IgG1, and OVA-specific IgG2a were also examined. The oral administration of 50 mg/mL astaxanthin inhibited the respiratory system resistance, elastance, newtonian resistance, tissue damping, and tissue elastance. Also, astaxanthin suppressed the total cell number, IL-4, and IL-5, and increased the IFN-γ in the BALF. In the sera, total IgE, IgG1, and OVA-specific IgG1 were reduced by astaxanthin exposure and IgG2a and OVA-specific IgG2a were enhanced via oral administration of astaxanthin. Infiltration of inflammatory cells in the lung, production of mucus, lung fibrosis, and expression of caspase-1 or caspase-3 were suppressed in OVA-induced asthmatic animal treated with astaxanthin. These results suggest that astaxanthin may have therapeutic potential for treating asthma via inhibiting Th2-mediated cytokine and enhancing Th1-mediated cytokine.
Inkjet Printing of Drug-Loaded Mesoporous Silica Nanoparticles—A Platform for Drug Development
Authors: Wickström Henrika , Hilgert Ellen , Nyman Johan , Desai Diti , Şen Karaman Didem , De Beer Thomas , Sandler Niklas , Rosenholm Jessica
Published: November 2017

Mesoporous silica nanoparticles (MSNs) have shown great potential in improving drug delivery of poorly water soluble (BCS class II, IV) and poorly permeable (BCS class III, IV) drugs, as well as facilitating successful delivery of unstable compounds. The nanoparticle technology would allow improved treatment by reducing adverse reactions of currently approved drugs and possibly reintroducing previously discarded compounds from the drug development pipeline. This study aims to highlight important aspects in mesoporous silica nanoparticle (MSN) ink formulation development for digital inkjet printing technology and to advice on choosing a method (2D/3D) for nanoparticle print deposit characterization. The results show that both unfunctionalized and polyethyeleneimine (PEI) surface functionalized MSNs, as well as drug-free and drug-loaded MSN–PEI suspensions, can be successfully inkjet-printed. Furthermore, the model BCS class IV drug remained incorporated in the MSNs and the suspension remained physically stable during the processing time and steps. This proof-of-concept study suggests that inkjet printing technology would be a flexible deposition method of pharmaceutical MSN suspensions to generate patterns according to predefined designs. The concept could be utilized as a versatile drug screening platform in the future due to the possibility of accurately depositing controlled volumes of MSN suspensions on various materials.
Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion
Authors: Zu Qiang , Yu Yanyan , Bi Xiaolin , Zhang Ren , Di Liuqing
Published: November 2017

This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN). The TMP-ME formulation was optimized in vitro with skin permeation experiments, using a uniform experimental design, guided by a pseudo-ternary phase diagram, in which the TMP skin permeation level and mean particle size were indices. The effects of MN pretreatment on skin permeation by TMP-ME were assessed using in vitro skin permeation, in vivo skin microdialysis, and pharmacokinetic studies in rats. The influence of MN pretreatment on the skin barrier function was evaluated by measuring the electrical resistance of rat skin before and after MN insertion. In the optimal formulation of TMP-ME, the weight percentages of Maisine® 35-1 (oil phase), Labrasol® (surfactant), and Transcutol® P (co-surfactant) were 7%, 30% and 10%, respectively, with 1.5% TMP loading. In the in vitro skin permeation study, MN-assisted TMP-ME exhibited a two-fold increase in a 24-h cumulative TMP permeation compared with TMP-ME alone (p < 0.05). In the skin microdialysis study, TMP in MN-assisted TMP-ME exhibited a 1.25-fold increase in Cmax, a 0.93-fold decrease in Tmax, and a 0.88-fold increase in AUC0–t (p < 0.05). Similarly, in the pharmacokinetic study, TMP in MN-assisted TMP-ME exhibited a 2.11-fold increase in Cmax, a 0.67-fold decrease in Tmax, and a 1.07-fold increase in AUC0–t (p < 0.05). The percutaneous electrical resistance of rat skin before and after MN insertion was 850 ± 50 Ω/cm2 and 283 ± 104 Ω/cm2 respectively, indicating that MN dramatically compromises the skin barrier. These results suggest that MN assistance increases the skin permeation rate and the extent of percutaneous absorption of TMP-ME, and that the mechanism may involve the reversible barrier perturbation effect. The rate and extent of percutaneous absorption of TMP-ME can be significantly enhanced by MN assistance, possibly because MN causes a reversible barrier perturbation effect on skin.
An In Vitro Study of the Photodynamic Effectiveness of GO-Ag Nanocomposites against Human Breast Cancer Cells
Authors: Shaheen Fozia , Hammad Aziz Muhammad , Fakhar-e-Alam Muhammad , Atif Muhammad , Fatima Mahvish , Ahmad Riaz , Hanif Atif , Anwar Saqib , Zafar Fatima , Abbas Ghazanfar , Ali Syed , Ahmed Mukhtar
Published: November 2017

Graphene-based materials have garnered significant attention because of their versatile bioapplications and extraordinary properties. Graphene oxide (GO) is an extremely oxidized form of graphene accompanied by the functional groups of oxygen on its surface. GO is an outstanding platform on which to pacify silver nanoparticles (Ag NPs), which gives rise to the graphene oxide-silver nanoparticle (GO-Ag) nanocomposite. In this experimental study, the toxicity of graphene oxide-silver (GO-Ag) nanocomposites was assessed in an in vitro human breast cancer model to optimize the parameters of photodynamic therapy. GO-Ag was prepared using the hydrothermal method, and characterization was done by X-ray diffraction, field-emission scanning electron microscope (FE-SEM), transmission Electron Microscopy (TEM), energy dispersive X-rays Analysis (EDAX), atomic force microscopy and ultraviolet-visible spectroscopy. The experiments were done both with laser exposure, as well as in darkness, to examine the phototoxicity and cytotoxicity of the nanocomposites. The cytotoxicity of the GO-Ag was confirmed via a methyl-thiazole-tetrazolium (MTT) assay and intracellular reactive oxygen species production analysis. The phototoxic effect explored the dose-dependent decrease in the cell viability, as well as provoked cell death via apoptosis. An enormously significant escalation of 1O2 in the samples when exposed to daylight was perceived. Statistical analysis was performed on the experimental results to confirm the worth and clarity of the results, with p-values < 0.05 selected as significant. These outcomes suggest that GO-Ag nanocomposites could serve as potential candidates for targeted breast cancer therapy.
Impact of High-Dose Multi-Strain Probiotic Supplementation on Neurocognitive Performance and Central Nervous System Immune Activation of HIV-1 Infected Individuals
Authors: Ceccarelli Giancarlo , Brenchley Jason M. , Cavallari Eugenio Nelson , Corano Scheri Giuseppe , Fratino Mariangela , Pinacchio Claudia , Schietroma Ivan , Fard Saeid Najafi , Scagnolari Carolina , Mezzaroma Ivano , Vullo Vincenzo , D’Ettorre Gabriella
Published: November 2017

Background: Gut microbiota has metabolic activity which influences mucosal homeostasis, local and systemic immune responses, and other anatomical systems (i.e., brain). The effects of dysbiosis are still poorly studied in Human Immunodeficiency Virus-1 (HIV-1) positive subjects and insufficient data are available on the impairment of the gut-brain axis, despite neurocognitive disorders being commonly diagnosed in these patients. This study evaluated the impact of a probiotic supplementation strategy on intrathecal immune activation and cognitive performance in combined antiretroviral therapy (cART) treated HIV-1 infected subjects. Methods: Thirty-five HIV-1 infected individuals were included in this study. At baseline (T0) a battery of tests was administered, to evaluate neurocognitive function and a lumbar puncture was performed to determine neopterin concentration in cerebrospinal fluid (CSF), as a marker of Central Nervous System (CNS) immune activation. Subsequently, a subgroup of participants underwent a 6-month course of multi-strain probiotics supplementation; this intervention group was evaluated, after probiotic treatment, with a second lumbar puncture and with repeated neurocognitive tests. Results: At T0, all participants showed impaired results in at least one neurocognitive test and elevated neopterin concentrations in CSF. After supplementation with probiotics (T6), the interventional group presented a significant decrease in neopterin concentration and a significant improvement in several neurocognitive tests. In contrast, no significant modifications were observed in the neurocognitive performance of controls between T0 and T6. The CNS Penetration Effectiveness Score of antiretroviral therapy did not show an influence from any of the investigated variables. Conclusions: Multi-strain probiotic supplementation seems to exert a positive effect on neuroinflammation and neurocognitive impairment in HIV-1 infected subjects, but large trials are needed to support the concept that modulation of the gut microbiota can provide specific neurological benefits in these patients.
A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity
Authors: Panagiotaki Katerina , Sideratou Zili , Vlahopoulos Spiros , Paravatou-Petsotas Maria , Zachariadis Michael , Khoury Nikolas , Zoumpourlis Vassilis , Tsiourvas Dimitris
Published: November 2017

Drug delivery systems that target subcellular organelles and, in particular, mitochondria are considered to have great potential in treating disorders that are associated with mitochondrial dysfunction, including cancer or neurodegenerative diseases. To this end, a novel hyperbranched mitochondriotropic nanocarrier was developed for the efficient co-delivery of two different (both in chemical and pharmacological terms) bioactive compounds. The carrier is based on hyperbranched poly(ethyleneimine) functionalized with triphenylphosphonium groups that forms ~100 nm diameter nanoparticles in aqueous media and can encapsulate doxorubicin (DOX), a well-known anti-cancer drug, and chloroquine (CQ), a known chemosensitizer with arising potential in anticancer medication. The anticancer activity of this system against two aggressive DOX-resistant human prostate adenocarcinoma cell lines and in in vivo animal studies was assessed. The co-administration of encapsulated DOX and CQ leads to improved cell proliferation inhibition at extremely low DOX concentrations (0.25 μΜ). In vivo experiments against DU145 human prostate cancer cells grafted on immunodeficient mice resulted in tumor growth arrest during the three-week administration period and no pervasive side effects. The findings put forward the potential of such targeted low dose combination treatments as a therapeutic scheme with minimal adverse effects.
Evaluating the Applicability of Four Latest Satellite–Gauge Combined Precipitation Estimates for Extreme Precipitation and Streamflow Predictions over the Upper Yellow River Basins in China
Authors: Su Jianbin , Lü Haishen , Wang Jianqun , Sadeghi Ali , Zhu Yonghua
Published: November 2017

This study aimed to statistically and hydrologically assess the performance of the four latest and widely used satellite–gauge combined precipitation estimates (SGPEs), namely CRT (CMORPH CRT), BLD (CMORPH BLD), CDR (PERSIANN CDR), 3B42 (TMPA 3B42 version 7) over the upper yellow river basins (UYRB) in china during 2001–2012 time period. The performances of the SGPEs were compared with the Chinese Meteorological Administration (CMA) datasets using the hydrologic model called Variable Infiltration Capacity (VIC) which is known as a land surface hydrologic model. Results indicated that irrespective of the slight underestimation in the western mountains and overestimation in the southeast, the four SGPEs could generally captured the spatial distribution of precipitation well. Although 3B42 exhibited a better performance in capturing the spatial distribution of daily average precipitation, BLD agreed best with CMA in the time series of watershed average precipitation, which resulted in BLD having a comparable performance to the CMA in the long-term hydrological simulations. Moreover, the potential for disastrous heavy rain mainly occurs in southeastern corner of the basin, and CRT and BLD comparisons showed to be closer to the CMA in the distribution of extreme precipitation events while 3B42 and CDR overestimated the extreme precipitation especially over the southeast of UYRB region. Therefore, CRT and BLD were able to match the high peak discharges very well for the wet seasons, while 3B42 and CDR overrated the high peak discharges. In addition, the four SGPEs performed well for the 2005 flood event but exhibited poorly when tested for the 2012 flood event. Results indicate that the application of the four SGPEs should be used with caution in simulating massive flood events over UYRB region.
Stochastic Models of Very High-Rate (50 Hz) GPS/BeiDou Code and Phase Observations
Authors: Shu Yuanming , Fang Rongxin , Liu Jingnan
Published: November 2017

In recent years, very high-rate (10–50 Hz) Global Navigation Satellite System (GNSS) has gained a rapid development and has been widely applied in seismology, natural hazard early warning system and structural monitoring. However, existing studies on stochastic models of GNSS observations are limited to sampling rates not higher than 1 Hz. To support very high-rate GNSS applications, we assess the precisions, cross correlations and time correlations of very high-rate (50 Hz) Global Positioning System (GPS)/BeiDou code and phase observations. The method of least-squares variance component estimation is applied with the geometry-based functional model using the GNSS single-differenced observations. The real-data experimental results show that the precisions are elevation-dependent at satellite elevation angles below 40° and nearly constant at satellite elevation angles above 40°. The precisions of undifferenced observations are presented, exhibiting different patterns for different observation types and satellites, especially for BeiDou because different types of satellites are involved. GPS and BeiDou have comparable precisions at high satellite elevation angles, reaching 0.91–1.26 mm and 0.13–0.17 m for phase and code, respectively, while, at low satellite elevation angles, GPS precisions are generally lower than BeiDou ones. The cross correlation between dual-frequency phase is very significant, with the coefficients of 0.773 and 0.927 for GPS and BeiDou, respectively. The cross correlation between dual-frequency code is much less significant, and no correlation can be found between phase and code. Time correlations exist for GPS/BeiDou phase and code at time lags within 1 s. At very small time lags of 0.02–0.12 s, time correlations of 0.041–0.293 and 0.858–0.945 can be observed for phase and code observations, respectively, indicating that the correlations in time should be taken into account in very high-rate applications.
A Similarity Analysis of Audio Signal to Develop a Human Activity Recognition Using Similarity Networks
Authors: García-Hernández Alejandra , Galván-Tejada Carlos E. , Galván-Tejada Jorge I. , Celaya-Padilla José M. , Gamboa-Rosales Hamurabi , Velasco-Elizondo Perla , Cárdenas-Vargas Rogelio
Published: November 2017

Human Activity Recognition (HAR) is one of the main subjects of study in the areas of computer vision and machine learning due to the great benefits that can be achieved. Examples of the study areas are: health prevention, security and surveillance, automotive research, and many others. The proposed approaches are carried out using machine learning techniques and present good results. However, it is difficult to observe how the descriptors of human activities are grouped. In order to obtain a better understanding of the the behavior of descriptors, it is important to improve the abilities to recognize the human activities. This paper proposes a novel approach for the HAR based on acoustic data and similarity networks. In this approach, we were able to characterize the sound of the activities and identify those activities looking for similarity in the sound pattern. We evaluated the similarity of the sounds considering mainly two features: the sound location and the materials that were used. As a result, the materials are a good reference classifying the human activities compared with the location.
Correction: S. Vogelgsang et al. Fusarium Mycotoxins in Swiss Wheat: A Survey of Growers’ Samples between 2007 and 2014 Shows Strong Year and Minor Geographic Effects. Toxins 2017, 9, 246
Authors: Vogelgsang Susanne , Musa Tomke , Bänziger Irene , Kägi Andreas , Bucheli Thomas , Wettstein Felix , Pasquali Matias , Forrer Hans-Rudolf
Published: November 2017

The authors wish to correct Figures 3–5 in this paper [1]. In all three figures, the y axis stated as a unit “milligram/kg” (mg/kg) instead of “microgram/kg” (µg/kg).
CONSTRUCTABILITY IN INDUSTRIAL PLANTS CONSTRUCTION: A BIM-LEAN APPROACH USING THE DIGITAL OBEYA ROOM FRAMEWORK
Authors: NASCIMENTO Daniel Luiz de Mattos , SOTELINO Elisa Dominguez , LARA Thiago Pires Santoloni , CAIADO Rodrigo Goyannes Gusmão , IVSON Paulo
Published: November 2017

One of the main problems the construction industry faces is the high cost and slow execution time due to inadequate planning, which results in poor use of human resources. A common solution for reducing time and costs is the adoption of prefabricated components (prefabs). This paper proposes a novel methodology for interdisciplinary man­agement of construction projects by integrating Building Information Modeling (BIM) and Lean Thinking to improve the production planning and control of pipe-rack modules in an industrial facility. The article first presents a literature review to assess the key synergies between BIM and Lean Thinking. These led to the development of a new integrated work methodology named Digital Obeya Room. This model focuses on the required workflows, the analysis of collected data, and the visual management of construction planning and control. A real-world empirical study in the Oil and Gas industry evaluated how the newly devised practices could improve prefabrication and preassembly planning. The pro­posed methodology was capable of reducing the welding-time in 8.7% related on global prefabrication average in con­struction projects from Fails Management Institute (FMI) prefabrication report survey 2017.
CASE STUDY ON SUBCONTRACTING ARRANGEMENTS IN THE SCAFFOLDING SUPPLY CHAIN OF A LIQUEFIED NATURAL GAS INFRASTRUCTURE PROJECT
Authors: LOPEZ Robert , CHONG Heap-Yih , MOON Sungkon , WANG Xiangyu
Published: November 2017

The objective of the study presented in this paper is to determine the characteristics of the scaffolding supply chain in a liquefied natural gas (LNG) infrastructure project. This research is significant as the outsourcing of scaffolding is integral to its use and productivity toward LNG infrastructure project completion. As such, this paper presents the re­search undertaken on the subcontracting of scaffold manufacturing, supplying and delivering. It focuses upon the organi­sations, management and control in scaffolding subcontracting. A comparative analysis of three organisations was car­ried out to reveal issues with current practice in manufacturing, supplying and delivering scaffold products for assembly onsite. Their management and control approaches are also compared and contrasted. It is found that, while the divided contract approach may help save costs, enhance market exposure and is ideal when choice of subcontractor is limited, its risks can impact upon the entire project and be difficult for the contractor to control. The limited background in scaf­folding studies and importance of subcontracting within LNG infrastructure projects has made this research timely. This paper identifies issues in relation to quality assurance, warranties and rework, which have the potential to mitigate any cost benefits obtained from subcontracting practices within this supply chain.
APPLICATION OF FUZZY AHP FOR RANKING AND SELECTION OF ALTERNATIVES IN CONSTRUCTION PROJECT MANAGEMENT
Authors: PRASCEVIC Natasa , PRASCEVIC Zivojin
Published: November 2017

The construction project management (CPM) is very important and large segment of entire project manage­ment (PM). Realisation of construction projects is usually long term process which requests significant financial, mate­rial, human and other resources to fulfil contracted obligations and achieve a good quality of works. Therefore, making good decisions with the satisfaction of various criteria is one of the main conditions to achieve planed business objec­tives and finish the project in contracted time with good quality. This paper proposes a new procedure for determination of the weights of criteria and alternatives in the Fuzzy analytic hierarchy process (FAHP) with trapezoidal fuzzy number using a new method for finding eigenvelues and eigenvectors of the criteria and alternatives, which is based on expected values of the fuzzy numbers and their products. Local and global fuzzy weights of the alternatives are determined using linear programming. In the paper a formula for ranking fuzzy numbers by reduced generalized fuzzy mean is also pro­posed, since ranking by the coefficient of variation is not always reliable. In the presented case study, applying proposed method, from imprecise input data are obtained enough accurate and useful results for rational ranking of alternatives related to the project realization.
LOAD-SETTLEMENT BEHAVIOUR OF MODEL PILE GROUPS IN SAND UNDER VERTICAL LOAD
Authors: SALES Mauricio Martines , PREZZI Monica , SALGADO Rodrigo , CHOI Yoon Seok , LEE Jintae
Published: November 2017

Model pile load testing is effective to study the load-settlement behaviour of pile foundations given the con­trolled environment in which the testing is done. This paper reports a testing program in a large calibration chamber involving individual piles and pile groups installed in sand samples of three different densities. Tests on both nondis­placement and driven piles are evaluated to assess the influence of the pile installation process on pile load-settlement response. A method is proposed to predict the load-settlement response of a pile group based on the response of a single pile. The method is shown to produce estimates that are in good agreement with measurements. The influence of pile group configuration, pile spacing, soil density and method of pile installation is discussed.
Properties of X-Ray Flux of Jets during the 2005 Outburst of Swift J1753.5−0127 Using the TCAF Solution
Authors: Jana Arghajit , Chakrabarti Sandip K. , Debnath Dipak
Published: November 2017

Galactic black hole candidate Swift J1753.5−0127 was discovered on 2005 June 30 by the Swift Burst Alert Telescope. We study the accretion flow properties during its very first outburst through careful analysis of the evolution of the spectral and the temporal properties using the two-component advective flow (TCAF) paradigm. RXTE proportional counter array spectra in

are fitted with the current version of the TCAF model fits file to estimate physical flow parameters, such as two-component (Keplerian disk and sub-Keplerian halo) accretion rates, properties of the Compton cloud, probable mass of the source, etc. The source is found to be in harder (hard and hard-intermediate) spectral states during the entire phase of the outburst with very significant jet activity. Since in the TCAF solution the model normalization is constant for any particular source, any requirement of significantly different normalization to have a better fit on certain days would point to an X-ray contribution from components not taken into account in the current TCAF model fits file. By subtracting the contribution using actual normalization, we derive the contribution of X-rays from the jets and outflows. We study its properties, such as its magnitude and spectra. We find that on some days, up to about 32% of X-ray flux is emitted from the base of the jet itself.
The Spin Distribution of Fast-spinning Neutron Stars in Low-mass X-Ray Binaries: Evidence for Two Subpopulations
Authors: Patruno A. , Haskell B. , Andersson N.
Published: November 2017

We study the current sample of rapidly rotating neutron stars in both accreting and non-accreting binaries in order to determine whether the spin distribution of accreting neutron stars in low-mass X-ray binaries (LMXBs) can be reconciled with current accretion torque models. We perform a statistical analysis of the spin distributions and show that there is evidence for two subpopulations among LMXBs, one at a relatively low spin frequency, with an average of

and a broad spread, and a peaked population at higher frequency with an average spin frequency of

. We show that the two subpopulations are separated by a cut-point at a frequency of

. We also show that the spin frequency of radio millisecond pulsars (RMSPs) does not follow a log-normal distribution and shows no evidence for the existence of distinct subpopulations. We discuss the uncertainties of different accretion models and speculate that either the accreting neutron star cut-point marks the onset of gravitational waves as an efficient mechanism to remove angular momentum or some of the neutron stars in the fast subpopulation do not evolve into RMSPs.
Gas-grain Fluorine and Chlorine Chemistry in the Interstellar Medium
Authors: Acharyya Kinsuk , Herbst Eric
Published: November 2017

We have studied the formation of fluorine- and chlorine-bearing species for a variety of dense interstellar conditions using a gas-grain network. Our homogeneous models have been constructed for low-temperature dense clouds, as well as warm-up regions. In addition to the observed species HF,

, HCl,

, and

, we have included a number of additional halogen-containing molecules, and explored their gas-phase and grain-surface chemistry. These molecules include neutral species such as Cl2, ClO, CCl, and HCCl, as well as the carbon–halogen species CH2Cl and CH3Cl, and ionic species such as

,

, CH3ClH+,

,

, and

. Predictions are made for the abundances of these species as functions of time, and comparisons are made with the observed abundances obtained for halogen species in dense regions, which include HF, HCl, CH3Cl, and CF+. The peak fractional abundance of the newly detected gas-phase CH3Cl is predicted to be

in our warm-up simulations, depending upon density and the age of the pre-warm-up phase after which warm-up begins. These values can be compared with the observed abundance of methyl chloride in the hot corino IRAS 16293-2422 if the abundance of methanol is known.
The Fate of Gas-rich Satellites in Clusters
Authors: Safarzadeh Mohammadtaher , Scannapieco Evan
Published: November 2017

We investigate the stellar mass-loss of gas-rich galaxies falling into clusters due to the change in the gravitational potential caused by the ram-pressure-stripping of their gas. We model the satellites with exponential stellar and gas disk profiles, assume rapid ram-pressure-stripping, and follow the stellar orbits in the shocked potential. Due to the change of the potential, the stars move from circular orbits to elliptical orbits with apocenters that are often outside the tidal radius, causing those stars to be stripped. We explore the impact of the redshift of infall, gas fraction, satellite halo mass, and cluster mass on this process. The puffing of the satellites makes them appear as ultra-diffuse galaxies, and the stripped stars contribute to the intracluster light. Our results show that these effects are most significant for less massive satellites, which have larger gas fractions when they are accreted into clusters. The preferential destruction of low-mass systems causes the red fraction of cluster galaxies to be smaller at lower masses, an observation that is otherwise difficult to explain.
Constraints on Super-Earth Interiors from Stellar Abundances
Authors: Brugger B. , Mousis O. , Deleuil M. , Deschamps F.
Published: November 2017

Modeling the interior of exoplanets is essential to go further than the conclusions provided by mean density measurements. In addition to the still limited precision on the planets’ fundamental parameters, models are limited by the existence of degeneracies on their compositions. Here, we present a model of internal structure dedicated to the study of solid planets up to ∼10 Earth masses, i.e., super-Earths. When the measurement is available, the assumption that the bulk Fe/Si ratio of a planet is similar to that of its host star allows us to significantly reduce the existing degeneracy and more precisely constrain the planet’s composition. Based on our model, we provide an update of the mass–radius relationships used to provide a first estimate of a planet’s composition from density measurements. Our model is also applied to the cases of two well-known exoplanets, CoRoT-7b and Kepler-10b, using their recently updated parameters. The core mass fractions of CoRoT-7b and Kepler-10b are found to lie within the 10%–37% and 10%–33% ranges, respectively, allowing both planets to be compatible with an Earth-like composition. We also extend the recent study of Proxima Centauri b and show that its radius may reach 1.94 

in the case of a 5 

planet, as there is a 96.7% probability that the real mass of Proxima Centauri b is below this value.
Constraining the Maximum Mass of Neutron Stars from Multi-messenger Observations of GW170817
Authors: Margalit Ben , Metzger Brian D.
Published: November 2017

We combine electromagnetic (EM) and gravitational-wave (GW) information on the binary neutron star (NS) merger GW170817 in order to constrain the radii

and maximum mass

of NSs. GW170817 was followed by a range of EM counterparts, including a weak gamma-ray burst (GRB), kilonova (KN) emission from the radioactive decay of the merger ejecta, and X-ray/radio emission consistent with being the synchrotron afterglow of a more powerful off-axis jet. The type of compact remnant produced in the immediate merger aftermath, and its predicted EM signal, depend sensitively on the high-density NS equation of state (EOS). For a soft EOS that supports a low

, the merger undergoes a prompt collapse accompanied by a small quantity of shock-heated or disk-wind ejecta, inconsistent with the large quantity

of lanthanide-free ejecta inferred from the KN. On the other hand, if

is sufficiently large, then the merger product is a rapidly rotating supramassive NS (SMNS), which must spin down before collapsing into a black hole. A fraction of the enormous rotational energy necessarily released by the SMNS during this process is transferred to the ejecta, either into the GRB jet (energy

) or the KN ejecta (energy

), also inconsistent with observations. By combining the total binary mass of GW170817 inferred from the GW signal with conservative upper limits on

and

from EM observations, we constrain the likelihood probability of a wide range of previously allowed EOSs. These two constraints delineate an allowed region of the

parameter space, which, once marginalized over NS radius, places an upper limit of

(90%), which is tighter or arguably less model-dependent than other current constraints.
Editorial
Authors: Lepoutre Thomas , Putois Olivier , Villa François
Published: November 2017

Mythe « scientifique » selon Freud, « génial » selon Lacan, le récit du Meurtre du père a eu, comme on sait, de considérables effets théoriques, non seulement au sein de la psychanalyse, mais également dans la philosophie politique, l’anthropologie ou l’histoire des religions. S’il découle au départ d’une ambition proprement clinique, ce mythe psychanalytique n’a cependant pu s’inventer qu’en donnant un rôle d’interlocuteur privilégié à des disciplines affines. Il y va donc d’une démarche « interdisciplinaire » avant la lettre, sur laquelle Freud fonde, le premier, la « recherche en psychanalyse ». C’est cette démarche dont ce numéro 22 commémore le centenaire, avec la publication de certaines des contributions prononcées à l’occasion d’un colloque interdisciplinaire international où il s'agissait – cent ans après – de réinterroger à la fois la postérité et l’actualité de Totem et Tabou au XXI e siècle.
Totem et Tabou : une méthode pour l’interdisciplinarité ?
Authors: Villa François
Published: November 2017

Une question est au cœur de cet article : pouvons-nous considérer qu’en publiant Totem et Tabou , Freud nous a proposé un modèle de méthode pour des recherches interdisciplinaires ? L’intérêt de la psychanalyse pour d’autres domaines du savoir ne pourrait s’entendre qu’en explorant les ressources qu’offre le recours à l’analogie et à la méthode des concordances qui sont aux fondements de Totem et Tabou. Il est montré comment le mouvement d’intérêt du psychanalyste pour d’autres méthodes que la sienne prend origine dans les difficultés du traitement psychique qui font objection à la théorie psychanalytique. L’article conduit à l’hypothèse que Freud met en œuvre une politique de l’acte dont témoigne son écriture.
Totem and Taboo , A Clinical Myth
Authors: Vanier Alain
Published: November 2017

Cet article relit Totem et Tabou comme façon obsessionnelle de sauver le père. Ce mythe de la fondation de « l’organisation sociale » s’oriente autour de la figure père, agencement essentiellement névrotique, dont rendent compte les mythes freudiens. Lacan en viendra, ultime interprétation de ces mythes paternels, à dégager le Père-du-Nom du Nom-du-Père : premier par rapport au Nom-du-Père, le Père-du-Nom est celui qui nomme. L’accent se déplace ainsi de l’énoncé à l’énonciation, à l’acte de dire, à ce trou dans le Réel que fait la nomination. On rejoint ainsi Freud : au commencement, on trouve non pas le défaut de penser, mais l’acte qui conditionne la possibilité même de penser.
From One Myth to the Other: From Totem and Taboo to Overview of the Transference Neuroses
Authors: Merot Patrick
Published: November 2017

Si tout oppose Totem et Tabou et Vue d’ensemble des névroses de transfert , il demeure quelque chose de commun dans leur inspiration, puisque chacun de ces textes fait surgir un mythe fondateur. Il s’agit donc de les rapprocher, afin de constater qu’un de ces mythes est devenu absolument central dans la pensée freudienne, alors que l’autre y a une place accessoire et quasi honteuse. Comment comprendre des destins théoriques aussi divergents ? Reprenant l’ensemble des enjeux inhérents à ces deux textes pratiquement concurrents, l’auteur soutient que prolonger l’élaboration du mythe proposé dans la Vue d’ensemble… aurait conduit le fondateur de la psychanalyse à des remaniements de fond de sa métapsychologie, auxquels, en 1915, Freud n’était pas prêt.
How Are We to Think About the Social Bond After Freud?
Authors: Puget Janine
Published: November 2017

Au fil de la notion d’incertitude, qui contraste avec l’épistémologie déterministe propre à la période d’émergence de la pensée freudienne, on propose une relecture du lien social actuel au prisme de la notion de Deux, ou dualité. Faisant place à une différence radicale, elle permet de théoriser l’impact de la réalité – notamment sociale et économique – sur le psychisme individuel, mais aussi la pluralité des lieux d’inscription du sujet, qui complexifient d’autant ses échanges avec autrui et accroissent le risque de repli narcissique sur le Un.
Comment penser après Freud le lien social ?
Authors: Puget Janine
Published: November 2017

Au fil de la notion d’incertitude, qui contraste avec l’épistémologie déterministe propre à la période d’émergence de la pensée freudienne, on propose une relecture du lien social actuel au prisme de la notion de Deux, ou dualité. Faisant place à une différence radicale, elle permet de théoriser l’impact de la réalité – notamment sociale et économique – sur le psychisme individuel, mais aussi la pluralité des lieux d’inscription du sujet, qui complexifient d’autant ses échanges avec autrui et accroissent le risque de repli narcissique sur le Un.
What Lacan Said About Totem and Taboo
Authors: Zafiropoulos Markos
Published: November 2017

Cet article entend ressaisir Totem et Tabou comme la clef de voûte de toute l’anthropologie psychanalytique au plan du cas, comme au plan de l’analyse des masses. Aussi, resituer de façon liminaire cet enjeu fondateur doit nécessairement nous conduire à le mettre en perspective, dans le retour à Freud , avec ce que Lacan disait de Totem et Tabou . L’article dégage ainsi les différents moments de la lecture lacanienne du mythe freudien – ces différents moments trouvant leur pivot essentiel dans le transfert de Lacan à Lévi-Strauss, au moment où Lacan refonde la psychanalyse, écartant sa lecture familialiste au profit d’une lecture structuraliste où les lois du langage et de la parole surclassent celles de la famille.
Ce que Lacan disait de Totem et Tabou
Authors: Zafiropoulos Markos
Published: November 2017

Cet article entend ressaisir Totem et Tabou comme la clef de voûte de toute l’anthropologie psychanalytique au plan du cas, comme au plan de l’analyse des masses. Aussi, resituer de façon liminaire cet enjeu fondateur doit nécessairement nous conduire à le mettre en perspective, dans le retour à Freud , avec ce que Lacan disait de Totem et Tabou . L’article dégage ainsi les différents moments de la lecture lacanienne du mythe freudien – ces différents moments trouvant leur pivot essentiel dans le transfert de Lacan à Lévi-Strauss, au moment où Lacan refonde la psychanalyse, écartant sa lecture familialiste au profit d’une lecture structuraliste où les lois du langage et de la parole surclassent celles de la famille.
Perverse and Narcissistic Strategies in the Link to the Object
Authors: Bernateau Isée
Published: November 2017

À travers le cas de l’amour proustien, tel qu’il se donne à voir dans À la recherche du temps perdu , l’auteur se propose de montrer que l’angoisse de séparation peut engendrer la mise en place d’une emprise perverse et narcissique sur l’objet, afin de tenter d’éviter de le perdre. L’amour, en ce qu’il suppose d’abandon et de reconnaissance de l’altérité de l’objet, achoppe sur l’indépendance catastrophique de l’objet. L’emprise perverse et narcissique sur l’objet répète, par le biais de l’identification à l’agresseur, l’emprise de la mère sur le narrateur. Au sein de ces stratégies perverses et narcissiques, la jalousie joue un rôle central, crainte perpétuelle du lâchage de l’objet et torture que le sujet s’auto-inflige, mais aussi ultime tentative pour tenter de tiercéiser une relation duelle perverse et narcissique à l’objet maternel.
The Silence of the “Addict”
Authors: Capart Noémie
Published: November 2017

Il s’agit de mettre en lumière la visée répressive que recouvrent le déni et le silence dont usent abondamment les patients alcooliques. Abordé dans ses spécificités, le déni alcoolique se voit mis à l’épreuve et confronté aux concepts de déni et de dénégation tels que décrits par Freud respectivement dans la perversion et dans l’hystérie, en vue d’établir un différentiel mettant en exergue une dynamique conflictuelle singulière, propre au « déni (de l’)alcoolique ». La dénégation se révélant chez ces patients mise en échec en raison d’un défaut de refoulement, le déni interviendrait comme tentative de suppléance, aux fins d’instaurer un silence qui peine à s’établir.
Le silence de l’« addict »
Authors: Capart Noémie
Published: November 2017

Il s’agit de mettre en lumière la visée répressive que recouvrent le déni et le silence dont usent abondamment les patients alcooliques. Abordé dans ses spécificités, le déni alcoolique se voit mis à l’épreuve et confronté aux concepts de déni et de dénégation tels que décrits par Freud respectivement dans la perversion et dans l’hystérie, en vue d’établir un différentiel mettant en exergue une dynamique conflictuelle singulière, propre au « déni (de l’)alcoolique ». La dénégation se révélant chez ces patients mise en échec en raison d’un défaut de refoulement, le déni interviendrait comme tentative de suppléance, aux fins d’instaurer un silence qui peine à s’établir.