bluuebunny/crossref_metadata_2025 huggingface dataset:
Perbandingan Efektifitas Pemberian Dzikir Dan Terapi Musik Religi Terhadap Penurunan Tingkat Kecemasan Pasien Pre Op Sectio Caesarea
Authors: Annisa Fausiyah , Irmawati Irmawati
Published: December 2022

Kecemasan adalah kekwatiran yang tidak jelas dan menyebar yang berkaitan dengan perasaan tidak pasti dan tidak berdaya. Penatalaksaan kecemasan ada 2 yaitu secara farmakologi dan nonfarmakologi, salah satu obat nonfarmakologi yaitu distraksi seperti dzikir dan terapi musik religi.Tujuan penelitian ini adalah untuk mengetahui perbandingan pemberian dzikir dan terapi musik religi terhadap penurunan tingkat kecemasan pasien pre op sectio caesarea di RSUD Haji Makassar. esain penelitian yang digunakan adalah penelitian experimental dengan pendekatan quasy experimental melalui rancangan penelitian two group pre-post test design. Jumlah sampel 74 responden. Penelitian ini menggunakan metode uji statistik yaitu uji t dengan kemaknaan 0,01. Didapatkan hasil adanya perbandingan pemberian terapi musik religi terhadap penurunan tingkat kecemasan pasien pre op sectio caesarea dengan nilai mean 25.65, deviasi 2.918 dan tingkat sig.0.001 Dengan nilai ρ 0,000 < α 0,01. Kesimpulan penelitian ini yaitu  bahwa terapi musik religi lebih efektif pada kecemasan pasien pre op sectio caesarea.
TEACHING BUSINESS ENGLISH CORRESPONDENCE IN THE DIGITAL ERA IN POLITEKNIK KOMPUTER NIAGA LPKIA BANDUNG
Authors: Liong Tjang Kian
Published: December 2022

Up to the present era of digital technology, printed-letters sent by post or electronic-mail have a very important role in businesses and government institutions. Meanwhile, the learning process of Business English Correspondence at the Polytechnic of LPKIA Bandung has not been much adjusted to the advancement of information and communication technology, so it might not suffice the needs of students who must work after they graduate. This study aims to describe the positive impact on the ability of students to produce and send business letters after studying the improved Business English Correspondence subject at the polytechnic mentioned above. The method used is descriptive analytics, and the data collection techniques are literature studies, questionnaires and interviews. The research comprises stages from analyzing pre-questionnaire evaluation result, revising and implementing the syllabus in the class, to analyzing post-questionnaire evaluation result. This study reveals that after completing the improved Business English Correspondence course, most students’ awareness and ability increases in producing and sending business English letters and e-mail more properly. The conclusion is that a number of improvements should be made to the Business English Correspondence learning contents and methods to be able to keep pace with the current advances in digital technology.
STRATEGIES IN TRANSLATING CHILDREN STORIES
Authors: Mahyudi Aditya , Prihandini Asih
Published: December 2022

The aims of this research is look for vocabulary in a story and determine the types of translation strategies into English-Indonesian and Indonesian-English. The data collected in this study were taken on a children's story entitled "The Emperor's New Clothes" which consisted of five analyzes and refer to Castillo's theory. (2019) Classifications of  translation strategy include addition, subtraction, cultural equivalents, synonyms, and adaptations. The use of a translation strategy like Procession is a form of adaptation from the Indonesian language prosesi. This word meaning has the same translation but the use of the meaning was differently. Furthermore, the research method used in this discussion is a qualitative method where the writer use data collection techniques with tables. As conclusion, the writer describes the translation strategy as a source of problem solving and must form a translation of words, phrases, or sentences based on linguistic rules.
ANALISIS TINDAK TUTUR ILOKUSI DALAM FILEM SPIRITED AWAY KARYA HAYAO MIZAYAKI
Authors: Meliana Igat , Antariksawan Antariksawan
Published: December 2022

This research was aimed to describe the use of speech utterances conveyed by speakers to the interlocutor in Mizaki Hayao's film Spirited Away. The form of illocutionary speech acts include the types of assertive, directive, commissive, expressive and declarative speech which means complaining, reporting, pleading, ordering, asking, threatening, promising, criticizing, blaming, thanking, apologizing, praising, and giving names. The method used in this study was qualitative descriptive method. Data was collected using the technique of listening, recording and taking notes. The results of this study is the data taken from the film. From the speech data, it is then classified according to the types of speech acts and their meanings. Based on the analysis, it can be concluded that the film Sporited Away by Hayao Mizaki contains illocutionary speech acts with assertive, directive, commissive, expressive and declarative speech having the meaning of complaining, reporting, pleading, ordering, asking, threatening, promising, criticizing, blaming, thanking, apologizing, praising and naming.

Penelitian ini bertujuan mendeskripsikan penggunaan tidak tutur yang disampaikan penutur kepada lawan tutur dalam filem Spirited Away karya Mizaki Hayao, berupa tindak tutur ilokusi dengan jenis tuturan asertif, direktif, komisif, ekspresif dan deklaratif yang bermakna mengeluh, melaporkan, memohon, memerintah, meminta, mengancam, menjanjikan, mengecam, menyalahkan, mengucapkan terimakasih, meminta maaf, memuji, serta memberikan nama. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Metode pengumpulan data yang digunakan dalam penelitian ini adalah teknik simak, rekam dan catat. Hasil penelitian ini berupa data jenis-jenis tindak tutur. Data tersebut kemudian diklasifikasikan sesuai dengan jenis tindak tutur dan maknanya. Berdasarkan hasil analisis tersebut, maka dapat disimpulkan bahwa pada filem Spirited Away karya Hayao Mizaki terdapat tindak tutur ilokusi dengan tuturan asertif, direktif, komisif, ekspresif dan deklaratif yang bermakna mengeluh, melaporkan, memohon, memerintah, meminta, mengancam, menjanjikan, mengecam, menyalahkan, mengucapkan terima kasih, meminta maaf, memuji serta memberi nama.
REALISASI PRINSIP KESANTUNAN DALAM TUTURAN WALIKOTA SURABAYA TRI RISMAHARINI PADA TALKSHOW DI TELEVISI
Authors: Thoriq Amiera
Published: December 2022

The objective of this research is to describe the realization of politeness principles within the speech of Tri Rismaharini, mayor of Surabaya which appeared in talkshows on television.  The main theory of the research is Geoffrey Leech’s Politeness Principles (1983).This qualitative research used data transcript noted from the talkshows that had her as a guest. The drawn conclusion is that all maxims in the politeness principles occurred in the conversations. Those are The Tact Maxim, The Generosity Maxim, The Approbation Maxim, The Modesty Maxim, The Agreement Maxim and The Maxim of Sympathy. 

Tujuan dari penelitian ini adalah untuk mendeskripsikan realisasi prinsip kesantunan dalam tuturan Tri Rismaharini, walikota Surabaya dalam beberapa talkshow di televisi. Teori utama yang digunakan adalah Prinsip Kesantunan yang digagas oleh Geoffrey Leech (1983). Data yang digunakan berupa transkip hasil teknik catat dari metode simak bebas libat cakap terhadap tayangan-tayangan talkshow yang mengundang Tri Rismaharini. Hasil penelitian ini menunjukkan bahwa prinsip kesantunan yang digunakan oleh Tri Rismaharini meliputi maksim kebijaksanaan, maksim kedermawanan, maksim kesederhanaan, maksim pujian dan maksim simpati.
TINDAK TUTUR EKSPRESIF MARAH DALAM FILM DEATH NOTE SEASON 1 (2015)
Authors: Hidayati Yanti , Syukur Andi Abd. Khaliq , Sukmana Hafiyyan Irham
Published: December 2022

This study aims to describe angry expressive speech acts and angry expressive speech act patterns in the film Death Note Season 1 (2015). Leech’s (1993) theory of pragmatics, Austin’s (1962) theory of speech acts, Searle’s (1969) theory of angry expression, and Yule’s (2014) theory of angry expression speech act were used in this study. This research was conducted by identifying the speech acts of angry expressions. The data that has been identified was analyzed using a qualitative descriptive method. The identification results contained 22 data of angry expressive speech acts. The analysis shows that the expressive speech act of anger is influenced by the context in the film. In addition, the pattern of expressive speech acts displayed has three tendencies. First, the meaning conveyed with the illocutionary has another meaning from the speaker. Second, utterances have direct and indirect meanings. Third, the utterance has a marker of angry expression but the speaker does not mean to be angry.
PEMBELAJARAN HATSUON MENGGUNAKAN TEKNIK DIKTE
Authors: Wahyuni Yuli , Al Badar M. Ikhwan , Hartanto Maharani Diastari , Ramadhan Jelang , Hapsari Gita Pramudyarsi Laksita
Published: December 2022

Research on Japanese pronunciation skills for Indonesian students is important. This research describes the student’s ability to listen to Japanese pronunciation / Hatsuon using dictation techniques and responses to dictation techniques in learning Japanese pronunciation. This research method uses a descriptive qualitative research instrument in the form of a questionnaire. The respondents in this study were students of the Japanese Language Education study program at the University of Muhammadiyah Yogyakarta, as many as 15 people who had Japanese language skills equivalent to N5. This research showed that almost all students tend to easily listen to long vowels and double consonants and distinguish sounds in the lines SA and SHA and JA and ZA. However, the TSU consonants at the beginning of the word are pretty challenging to catch appropriately. Then from the results of the questionnaire distribution, it can be seen that students think that the dictation technique is an excellent alternative to studying Japanese pronunciation.
A Methodology of Assessing Spatial and Functional Heterogeneity in A Ecosystem
Authors: Liu Huan
Published: December 2022

Article 4: A Methodology of Assessing Spatial and Functional Heterogeneity in A Ecosystem / 生态系统的空间和功能异质性评价方法研究 Author: Liu Huan, Master of Science (First Class Honours), The University of Auckland
Clinicopathologic and Molecular Features of Pancreatic Ductal Adenocarcinomas Harboring Alterations in COMPASS-like Complex Genes
Authors: Hissong Erika , Zhao Lili , Shi Jiaqi
Published: December 2022

Context.—

Recent genome-wide sequencing studies have identified a subset of pancreatic ductal adenocarcinomas (PDACs) harboring significant alterations in epigenetic regulation genes, including the COMPASS-like complex genes. Whether this subset of PDACs has specific histologic characteristics or carries prognostic or therapeutic implications is unknown.

Objective.—

To determine the specific clinicopathologic and molecular features of PDACs carrying mutations in COMPASS-like complex genes.

Design.—

We analyzed a series of 103 primary and metastatic PDACs with comprehensive molecular profiling, including 13 PDACs carrying loss-of-function COMPASS-like complex gene alterations (study cohort). Another 45 patients carrying PDACs with wild-type COMPASS-like complex genes were used as the control group.

Results.—

PDACs within the study cohort were smaller, harboring frequent areas of poor differentiation and concurrent alterations in KRAS, TP53, SMAD4, and CDKN2A. A subset of metastatic PDACs from the study cohort showed squamous differentiation. There was a trend toward decreased survival in the study group. We further interrogated 2 public data sets and found that PDACs with COMPASS-like complex gene alterations have increased rates of TP53 mutation, body-tail location, poor differentiation or undifferentiated histology, and a higher death rate.

Conclusions.—

COMPASS-like complex gene alterations likely represent a subset of more aggressive PDACs with poor or squamous differentiation histologically and increased concurrent TP53 mutations. These findings may have potential prognostic and therapeutic implications.
Association of Minimal Residual Disease by a Single-Tube 8-Color Flow Cytometric Analysis With Clinical Outcome in Adult B-Cell Acute Lymphoblastic Leukemia: A Real-World Study Based on 486 Patients
Authors: Liao Hongyan , Jiang Nenggang , Yang Ying , Zhang Xin , Chen Jiao , Lai Hongli , Zheng Qin
Published: December 2022

Context.—

Minimal/measurable residual disease (MRD) measured by molecular and multiparametric flow cytometry (MFC) has been proven to be predictive of relapse and survival in patients with B-cell acute lymphoblastic leukemia (B-ALL). A universally applicable antibody panel at a low cost but without compromising sensitivity and power of prognosis prediction in adult B-ALL remains unestablished.

Objective.—

To report our experience of using a single-tube 8-color MFC panel to measure the MRD status as a prognostic indicator in adult B-ALL patients.

Design.—

We retrospectively analyzed the characteristics, MRD status, and prognosis of adult B-ALL based on a large real-world cohort of 486 patients during a 10-year period.

Results.—

MRD assessed by MFC and polymerase chain reaction (PCR) assays for BCR-ABL+ patients showed concordant results in 74.2% of cases. MRD− status by our MFC panel could clearly predict a favorable relapse-free survival (RFS) and overall survival (OS) both at the end of induction and at the end of 1 consolidation course. Patients with continuous MRD− and with at least 1 MRD− result showed a favorable RFS and OS compared with those with at least 1 MRD+ result and continuous MRD+, respectively.

Conclusions.—

The single-tube 8-color MFC panel demonstrated a low cost, decent sensitivity, and comparability with polymerase chain reaction–MRD but an excellent performance in predicting RFS and OS, and thus could potentially be taken as a routine indicator in the evaluation of the treatment response for adult patients with B-ALL.
Consideraciones metodológicas en el estudio de la discriminación laboral percibida: protocolo de una revisión panorámica
Authors: Bravo Gonzalo , Fuentes-Garcia Alejandra , Arriagada María , Castellucci Hector Ignacio
Published: December 2022

Introduction Perceived discrimination is a complex phenomenon of study and has significant repercussions on people's health. Many studies confirm the negative effects of stress on workers' health in the workplace, affecting both their physical and mental health. However, there is no consensus when investigating the construct of "perceived work discrimination". Objective To examine how perceived workplace discrimination has been investigated, considering its association with health and occupational outcomes. Methods A scoping review will be performed according to the PRISMA guidelines for scoping reviews and the Joanna Briggs Institute. We will search for published articles in english and spanish between 2000 and 2022 in the Scopus, MEDLINE/PubMed, and PsycInfo databases. Through the Rayyan application, two reviewers will independently select titles and abstracts. Then, they will review the full texts. Subsequently, relevant information about the selected articles will be extracted, and their methodological quality will be evaluated. Finally, a narrative synthesis of the main results found will be made. Discussion We expect the findings to improve methodological aspects when investigating perceived workplace discrimination, facilitating decision-making for those researchers who wish to address perceived work discrimination.
An Empirical Study On Vietnam’s Participation in The Global Agricultural Value Chain
Authors: Nguyen Thi Phuong Linh , Vu Thanh Huong
Published: December 2022

Agriculture is one of the vital economic sectors in the economic development of Vietnam. Using two datasets from UNCTAD's MRIO database, the paper aims to assess Vietnam’s participation in the global agricultural value chain in 2010-2017 and compare it with ASEAN-5 countries’ participation by calculating backward linkage, forward linkage, position, and participation index. Research results show that Vietnam is moving towards the upstream place and the country’s level of participation tends to increase mainly due to forward linkage participation. There is more diversification in the agricultural export markets but a high concentration of the import markets in Asia. While some commodity groups such as forestry, pocks, sugarcane, rubber, and paddy have more advantages when participating in the global value chain, other groups such as fishery, poultry, cow, and tea have faced passive participation. In comparison with ASEAN-5 countries, Vietnam's participation index is relatively high, but its position index lags. The paper ends by providing some policy implications for Vietnam to improve its participation in the agricultural global value chain, focusing on taking advantage of free trade agreements, applying advanced technologies in agriculture, strengthening brand names for agricultural products, and improving the quality of logistics services.
Composição pela concatenação de fragmentos independentes
Authors: Oliveira Liduino José Pitombeira de
Published: December 2022

Neste artigo, é descrito um plano de trabalho composicional, de natureza pedagógica, partindo dos conteúdos teóricos dos seis capítulos do livro de Straus (2013) intitulado Introdução à Teoria Pós-Tonal. A ideia central consistiu em demonstrar o planejamento, a composição e a posterior concatenação de seis fragmentos independentes, com participação ativa de cinco alunos de composição, focalizando os seguintes tópicos: tipos intervalares, classes de conjuntos, operações entre conjuntos de classes de alturas, relações de contorno, relação Z, formações escalares, dodecafonismo, combinatoriedade, derivação, multiplicação e serialismo integral. Concomitantemente ao referencial teórico pós-tonal, cinco premissas pedagógicas originais serviram de guia durante cada etapa do trabalho. Os seis fragmentos, cada um com aproximadamente trinta segundos, foram, em seguida, concatenados, levando-se em consideração seis procedimentos originais propostos pelo autor, de maneira a produzir uma obra coerente de cerca de três minutos, para quinteto de sopros.
Origins of Modern Idea of an United Europe
Authors: Sinica Vytautas
Published: December 2022

The article is focused on the sources of the idea of a united Europe, which are also relevant to Lithuania, both theoretically and practically. Practically, Lithuanian society supports the idea of a united Europe enthusiastically and is deeply interested in its success and stability. Theoretically, Lithuanian culture developed and flourished in the context of European civilization, first Christian and later modern. In recent studies, it is usual to emphasise “Europeanisation” of Lithuania and the parallels between the multiethnic medieval Grand Duchy of Lithuania and contemporary Europe, united in diversity and openness. The fact that our “Europeanisation” unfolded at the same time as Christendom was discovering its new modern European identity is left on the margins.
Ptolemy’s Geography Studies: Who Lives and Who Does Not Live on the Right Bank of the Vistula
Authors: Alekna Darius
Published: December 2022

The research is carried out using several analytical tools, the most important of which was to identify and keep track of the sequences of the neighbouring tribes, since Ptolemy himself testified (I, 19, 2) that when speaking of the peoples, he was concerned to indicate their relationships with one another. This means that the peoples mentioned side by side in his text probably lived close to one another and could not be scattered over a wide geographical area. Another important tool for us is to notice and consider Ptolemy’s specific patterns of presentation, which recur throughout his work. A case where the author was not quite consistent with his usual way of presentation is likely to signal a problem with the sources. Finally, we based our hypothesis on the fact that the connectives that separate Ptolemy’s phrases separate the data from different sources as well.
Morphological operations on temporal intuitionistic fuzzy sets
Authors:   Department of Mathematics, Vellalar College for Women, Parvathi R. , Yuvapriya C. ,   PG Department of Mathematics, Vellalar College for Women
Published: December 2022

This paper is devoted to develop the theory of temporal intuitionistic fuzzy sets. The matrix representation of a TIFS is also introduced for easy symbolization. In addition to a few basic operations, length of a TIFS and its properties are discussed. Morphological operations on temporal intuitionistic fuzzy sets are defined using (i) mathematical operations, (ii) structuring element, (iii) inclusion indicators, and (iv) temporal intuitionistic fuzzy divergence and verified with suitable examples.
Association between type 2 diabetes and 5-year overall survival in early-stage pancreatic cancer: a retrospective cohort study
Authors: Tang Zhiyin , Xu Wanfeng , Zhang Mingming
Published: December 2022

Background

This study examined the association between type 2 diabetes mellitus (T2DM) and 5-year overall survival (OS) in patients with pancreatic cancer (PC).

Methods

This retrospective cohort study included patients diagnosed with stage I/II PC at Shengjing Hospital of China Medical University from January 2012 to December 2017. All patients had pancreatic ductal adenocarcinoma or its subtypes. The outcome was the 5-year OS rate based on data from the patient charts. Data analysis was performed using SPSS 22.0

Results

A total of 238 patients were included: 72 with T2DM and 166 without T2DM. There were significant differences in blood glucose levels and OS between the two groups (all P < 0.05). The median OS was 11.4 (95% confidence interval CI [8.49–14.31]) months in the T2DM group and 16.3 (95% CI [12.44–20.16], P = 0.023) months in the non-T2DM group. After adjustment for confounders, T2DM was an independent factor affecting 5-year OS (P = 0.010). Compared with non-T2DM patients, T2DM patients had a higher risk of death (HR = 1.475, 95% CI [1.096–1.985]).

Conclusions

T2DM is associated with 5-year OS in patients with PC.
Касситерит — пять тысяч лет истории: новые грани, "Природа"
Authors: Петроченков Д.А.
Published: December 2022

Касситерит на протяжении пяти тысяч лет служит основным источником олова. При этом он по оптическим характеристикам, твердости и разнообразию окраски не уступает популярным ювелирным минералам, оставаясь малоизвестным. В статье рассказывается о технологии облагораживания и обработки касситерита, включая применение нетрадиционных видов огранки, что позволяет широко использовать этот минерал в ювелирных изделиях.
Природные парки Волгоградской области, "Природа"
Authors: Овчарова А.Ю. , Казиева З.М.
Published: December 2022

Экологический туризм стремительно набирает популярность. На территории Волгоградской обл. расположены семь природных парков. Они включают природные комплексы и объекты, имеющие экологическую, культурно-историческую и эстетическую ценность, и предназначены для использования в природоохранных и рекреационных целях. В статье рассматривается туристический потенциал природных парков: транспортная доступность, наличие гостиниц, визит-центров, количество и качество эколого-просветительских маршрутов. Важным представляется также наличие удобного доступа к информации о парках в сети Интернет.
Следы «эпохи пароходов» на Нижнем Дону, "Природа"
Authors: Матишов Г.Г. , Степаньян О.В.
Published: December 2022

С конца XIX и до середины XX в. по Нижнему Дону ходило множество пароходов, работавших на угле. Пароходство имело исключительно важное экономическое значение, а самые крупные порты находились в Таганроге, Ростове-на-Дону и Азове. Для нужд пароходства была существенно изменена природная система донской дельты: проложены судоходные каналы, углублен фарватер, изменено общее направление и объемы стока. Сегодня в осадках дельты обнаружен крупный прослой пережженного угля — шлака, выброшенного за борт и захороненного в донном грунте. Угольный шлак становится важным техногенным индикатором «эпохи пароходов», его изучают для оценки особенностей осадконакопления, изменения гидрографической сети, интенсивности судоходства и освоения новых территорий в XIX и XX в.
КОСМОС АРХИМЕДА, "Земля и Вселенная"
Authors: Кузьмин А.В.
Published: December 2022

Открытия, сделанные Архимедом с опорой на своего предшественника Аристарха Самосского, позволившие измерить диаметры космических сфер, превратили рассуждения о размере Космоса в область науки. У Архимеда впервые в истории астрономии появляются реальные числовые оценки размеров всех планетных сфер. В основе этих измерений лежала приблизительная, чрезвычайно завышенная оценка размера Земли. Ответ на вопрос о ее происхождении найден в письменных источниках, фиксирующих поздний вариант устной древнеиранской мифологической традиции. В одних фрагментах мифологических преданий, в форме откровения, сообщается размер Земли, завышенный приблизительно в 5.5 раз, в других – определяются как «беспредельный».
СУДЬБА ИНЖЕНЕРА ПЕТРА ПАЛЬЧИНСКОГО НА ФОНЕ СТРОИТЕЛЬСТВА КОММУНИЗМА, "Энергия: экономика, техника, экология"
Authors: Ваганов А.
Published: December 2022

До сих пор вызывает ожесточённые споры историков, социологов, экономистов, политиков вопрос: почему СССР оказался неспособен воспользоваться в полной мере результатами своего впечатляющего вступления на путь технической модернизации Ещё в 1960 году известный американский экономист Роберт Кэмпбелл подчёркивал, что темпы экономического роста в СССР почти в два раза выше, чем в США. Кэмпбелл (ставший, кстати, впоследствии одним из ведущих в США специалистов по Советскому Союзу) приходил к выводу: “…коль скоро имеется разница в темпах роста, русские неизбежно догонят нас; а если она будет оставаться на нынешнем уровне, это произойдет довольно скоро”.
МИКРОПЛАСТИК В ОКРУЖАЮЩЕЙ СРЕДЕ ТАГАНРОГА, "Наука юга России"
Authors: Анциферова М.А. , Беспалова Л.А.
Published: December 2022

Представлены результаты исследования загрязнения микропластиком прибрежной зоны Азовского моря в районе Таганрога, дана оценка уровня содержания микропластика в пляжевых и донных отложениях, в воде и в атмосферном воздухе. Микропластиком является любой тип пластикового фрагмента длиной менее 5 мм. Он попадает в окружающую среду из всевозможных источников, как промышленных, так и сельскохозяйственных и бытовых. Целью работы является оценка загрязненности окружающей среды Таганрога микропластиком, определение его морфологических, морфометрических характеристик, оценка степени деградации и состава микрочастиц. В ходе исследований был проведен отбор проб в прибрежной зоне Таганрога и отобраны 21 проба пляжевых отложений, 7 проб донных осадков, 14 проб воды и 5 проб аэрозолей. При дальнейшей обработке был применен модифицированный метод NOAA, который включает следующие манипуляции: сушку, просеивание, фильтрацию, плотностное разделение, жидкое окисление, визуальную сортировку с использованием стереомикроскопа Микромед МС-1 вар. 2C Digital, определение степени деградации микропластика с помощью микроскопа VEGA II LMU и идентификацию химического состава обнаруженных частиц с помощью ИК-Фурье спектрометра JASCO FT/IR-6800. В результате проведенных исследований было установлено, что микропластик присутствует в 100 % проб. В пляжевых отложениях содержание частиц достигало 154 шт./м, в донных 145 шт./кг, в воде 119 шт./л. Самые высокие концентрации были зафиксированы в южной части города (ул. Ломакина). В пробах атмосферного воздуха наибольшее количество выпадений составляло 918 частиц на 1 м в сутки (ул. Чехова).
ДИАГНОСТИКА ПРОЦЕССОВ ДЕГРАДАЦИИ ПОЧВ ЮГО-ВОСТОКА РОСТОВСКОЙ ОБЛАСТИ С ПРИМЕНЕНИЕМ ГЕОИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ, "Наука юга России"
Authors: Жумбей А.И. , Безуглова О.С.
Published: December 2022

Приведены результаты диагностики процессов деградации почв юго-восточных районов Ростовской области. Для определения степени дигрессии пастбищ и состояния лесополос обследовано 85 точек: 3 пастбищных и 1 фоновый участок, на которых заложены почвенные разрезы и описаны растительные сообщества (площадки геоботанического описания 100 м); 76 пробных площадок по 225 м, на которых определено проективное покрытие для последующего статистического сопоставления значений этого показателя и индекса SAVI; 4 площадки, на которых изучен видовой состав растительных сообществ на местах с видимыми признаками нарушения древостоя на территории одной из крупнейших полезащитных лесополос в Дубовском районе. Собранные данные обработаны в программной среде ESRI ArcGIS, и на их основе построены карты проективного покрытия обследованных участков. Деградация пастбищных фитоценозов имеет локальный характер ввиду изменения системы животноводства – отгонный тип со временем был частично заменен на регулярный выпас вблизи населенных пунктов и ферм, вокруг которых образуются кольцеобразные очаги дигрессии. Деградационные процессы пастбищных участков характеризуются разрушением дернового слоя, утяжелением фракционного состава на фоне разрушения мезоагрегатной структуры, локальным понижением продуктивности пастбищных угодий в пределах 0,1 г/га (20% от среднего значения). Полученные результаты дают возможность судить о неравномерном использовании территории пастбищ, приводящем к локальной дигрессии и риску развития эрозии почвенного покрова. Лесные насаждения в сухостепной зоне подвержены экстремальной климатической нагрузке и не имеют достаточного ресурса для самообновления. Деревья первого яруса погибают, оставляя деревья второго яруса и кустарники под прямыми солнечными лучами, это сопровождается сменой травянистых сообществ подлеска сообществами рудеральных растений. В настоящее время полезащитные лесонасаждения нуждаются в проведении работ по их искусственному восстановлению, особенно лесополосы в сочетании с сельскохозяйственными землями.
Allocation of Subjects in an Educational Institution by Pascal Triangular Approach
Authors: Singh Arun Pratap
Published: December 2022

The classical assignment problems cannot be successfully used for the real-world situation it is because the work efficiency varies to some extent from person to person hence, the use of fuzzy assignment problems is more appropriate. Based on the performance of the previous record in this study, on taking the scores obtained by the Chairman, by Course Director, by faculty members, and the student’s feedback, we applied Pascal triangular approach in fuzzy assignment problem for allocating the subjects in a department of coming semester. A study of the technique for 4 jobs and 4 persons has been made.
Effect of Agronomic Management on Soil Microclimatic Parameters and Root Yield of Sida Hemp (Sida alnifolia L.)
Authors: Priyadarsini P. T. Vidhu , Sindhu P. V. , Menon Meera V.
Published: December 2022

Agronomic management exhibits great influence on growth and yield of crops by modifying physical, chemical and biological properties of soil and plants. Field experiment was conducted during June to December, 2018 to assess the effect of agronomic management viz. light intensity, application of manuring and weed management on soil microclimatic variations and its effects on root yield of Sida hemp (Sida alnifolia L.). The treatments included two levels of light intensity (open and 50 per cent shade), two levels of  manuring (no manure and FYM@10 t ha-1), and four weed management practices (black polythene mulching, organic mulching with paddy straw @ 5 t ha-1, hand weeding at 1,3,5 MAP (Month after planting) and no weeding). Higher soil temperature at 10 cm depth was observed in open condition and under black polythene mulching throughout the growing period. Higher soil moisture content at 15 cm depth was recorded under shade and black polythene mulching.  Black polythene mulching resulted in increase in soil temperature and soil moisture content by almost two percent as compared to bare soil in open condition. The highest root yield of 14.66 t ha-1 was noticed in plots with black polythene mulching with FYM under open condition. Soil temperature and light intensity showed positive correlation with root yield.
Nucleated Red Blood Cells as a Prognostic Marker in Neonatal Intensive Care Unit
Authors: Arab Walaa Salah El-Deen Mohamed Abo , Saad Mohamed Attia , Hagag Adel Abd El-haleim , El-Sharkawy Hamed Mohamed
Published: December 2022

Background: Nucleated red blood cells (NRBCs) are normally present in the circulation of the fetus during the intrauterine life but they disappear early in the first 10 postnatal days in healthy neonates. We aimed to assess the relations between NRBCs and the prognosis in neonatal intensive care unit (NICU).

Patients and Methods: This prospective cohort study was carried out on 120 neonates admitted to Tanta University NICU from January 2021 to January 2022. Full maternal history taking, detailed history of resuscitation and complete systemic examination were done. Three samples for complete blood picture analysis & NRBCs count were taken in 1st 24 hours of admission, between 2nd -10th day, and after 10th day of admission.

Results: 32 cases out of 120 cases had NRBCs beyond normal range (>10/100WBCs) in the 1st 24 hours of admission; 28 of them died (87.5%). 19 cases had NRBCs beyond normal range between the 2nd and 10th day; 17 of them died (89.5%). 31 cases had detectable NRBCs after 10th day; NRBCs 30 of them died (96.8%). There was a statistically significant positive correlation between the presence of NRBCs count above normal range and the number of deceased cases (P = 0.001).

Conclusions: Nucleated red blood cells monitoring is a promising affordable marker that can predict poor prognosis in NICU.
Assessment of Depression and Adherence to Guideline-Directed Medical Therapies Following Percutaneous Coronary Intervention
Authors: Lapa Matthew E. , Swabe Gretchen M. , Rollman Bruce L. , Muldoon Matthew F. , Thurston Rebecca C. , Magnani Jared W.
Published: December 2022

Importance

Depression is associated with increased risk of primary and secondary cardiovascular events. Medication adherence may play an essential role.

Objective

To evaluate the association of depression and 12-month adherence to guideline-directed medical therapies (eg, antiplatelet agents, β-blockers, renin-angiotensin-aldosterone system inhibitors [ie, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers], and statins) following percutaneous coronary intervention.

Design, Setting, and Participants

This retrospective cohort study included individuals who underwent percutaneous coronary intervention from January 1, 2014, to December 31, 2019. Data were collected from a large US health claims database and analyzed between February and August 2022.

Main Outcomes and Measures

Proportion of days covered (PDC) for classes of guideline-directed medical therapies, with 12-month adherence categorized as adequate (PDC ≥80% to <90%) or optimal (PDC ≥90%). Multivariable-adjusted regression models were used to evaluate the association of depression with adherence; models incorporated demographic characteristics, comorbid medical and psychiatric conditions, depression treatment, and guideline-directed medical therapy treatment adjustment. The hypothesis was that those with depression would have lower odds of either adequate or optimal adherence to agents essential for guideline-directed medical therapy.

Results

Of 124 443 individuals (mean [SD] age, 69.3 [10.6] years; 41 430 [33.3%] female sex; 3694 [3.0%] Asian, 12 611 [10.1%] Black, and 12 337 [9.9%] Hispanic individuals) who received percutaneous coronary interventions, 20 711 (16.6%) had a diagnosis of depression. Those with depression were significantly less likely to obtain adequate 12-month adherence to antiplatelets (odds ratio [OR], 0.80; 95% CI, 0.77-0.85), β-blockers (OR, 0.84; 95% CI, 0.80-0.88), and statins (OR, 0.88; 95% CI, 0.85-0.93) than those without depression; there was no association between depression and adherence to renin-angiotensin-aldosterone system inhibitors (OR, 0.93; 95% CI, 0.85-1.00). Those with depression had similarly decreased likelihood of optimal 12-month adherence to antiplatelets, β-blockers, and statins as well as renin-angiotensin-aldosterone system inhibitors (OR, 0.87; 95% CI, 0.82-0.94).

Conclusions and Relevance

In this cohort study, patients with depression were less likely to achieve adequate or optimal adherence to medications essential to guideline-directed medical therapies following percutaneous coronary intervention compared with those without depression. Recognition of depression may facilitate targeted interventions to address medication adherence and thereby improve secondary cardiovascular disease prevention.
Application of Nanotechnology in Thrombus Therapy
Authors: Zhou Shuyin , Zhao Wenbo , Hu Jinglei , Mao Chun , Zhou Min
Published: December 2022

A thrombus is a blood clot that forms in the lumen of an artery or vein, restricting blood flow and causing clinical symptoms. Thrombosis is associated with many life‐threatening cardiovascular diseases. However, current clinical therapeutic technologies still have many problems in targeting, enrichment, penetration, and safety to meet the thrombosis treatment needs. Therefore, researchers devote themselves to developing nanosystems loaded with antithrombotic drugs to address this paradox in recent years. Herein, the existing thrombosis treatment technologies are first reviewed; and then, their advantages and disadvantages are outlined based on a brief discussion of thrombosis's definition and formation mechanism. Furthermore, the need and application cases for introducing nanotechnology are discussed, focusing on thrombus‐specific targeted ligand modification technology and microenvironment‐triggered responsive drug release technology. Then, nanomaterials that can be used to design antithrombotic nanotherapeutic systems are summarized. Moreover, a variety of drug delivery technologies driven by nanomotors in thrombosis therapy is also introduced. Last of all, a prospective discussion on the future development of nanotechnology for thrombosis therapy is highlighted.
Single‐Component White Circularly Polarized Luminescence in Chiral 1D Double‐Chain Perovskites
Authors: Chai Chao‐Yang , Zhang Qing‐Kai , Jing Chang‐Qing , Han Xiang‐Bin , Liu Cheng‐Dong , Liang Bei‐Dou , Fan Chang‐Chun , Chen Zhong , Lei Xiao‐Wu , Stroppa Alessandro , Agbaoye Ridwan Olamide , Adebayo Gboyega Augustine , Zhang Chun‐Feng , Zhang Wen
Published: December 2022

Circularly polarized luminescence (CPL) with polychromatic colors has been widely studied due to its great applications in chiroptical, optoelectronics, and spintronics. However, the realization of white CPL in single‐component solid‐state materials remains a great challenge and suffers from the incompatibility between high efficient luminescence and large asymmetric discrimination. Here, by exploiting self‐trapped exciton mechanism and chirality induction strategy, a pair of 1D chiral perovskites, (RR/SS‐DMPZ)PbBr4 (where DMPZ = cis‐2,5‐dimethylpiperazine divalent cation), is reported to achieve white CPL with both high quantum yield of 28.4% and large photoluminescence asymmetry factor |glum| of 2.32 × 10−2. The crystal structures are featured by 1D double‐chain structure composed of distorted octahedra with short PbPb distances as the structural origin of the high photoluminescence yield. The high |glum| value is caused by efficient chiral induction due to the multiple hydrogen bonds between the chiral host composed of the enantiopure organic cations containing two stereocenters and the inorganic emitting guest. The self‐trapped exciton emission mechanism is demonstrated by density functional theory calculations and variable‐temperature photoluminescence and femtosecond‐transient absorption spectroscopy studies. The photo‐luminescent white light‐emitting diodes exhibit good stability and can be used as single‐component white light emitters. This work provides applicable strategies to explore single‐component white CPL emitters.
Diastereoselective Synthesis of Dispiropyrrolidinyloxindoles via DBU‐Promoted [3+2]‐Cycloaddition of Cyclic Pyridinium Ylides and α,β‐Unsaturated Ketones
Authors: Liang Xiayu , Wang Bingren , Sun Jiayang , Li Yaqi , Zeng Qingle
Published: December 2022

A novel [3+2]‐cycloaddition reaction of cyclic pyridinium ylides and α,β‐unsaturated ketones derived from indanones for the synthesis of dispiropyrrolidinyloxindoles is described herein. Various types of dispiropyrrolidinyloxindoles can be conveniently accessed with moderate to good yields and up to >99 : 1 dr from easily available pyridinium salts which bear an electron‐withdrawing group on the pyridine ring under mild conditions for short reaction time.
A human lower third molar from the Acheulean site of Cueva del Ángel (Lucena, Córdoba, Spain)
Authors: Bermúdez Francisco J. , Martínez de Pinillos Marina , Medina‐Lara Francisca , Barroso‐Medina Cecilia , Cabral‐Mesa Antonio L. , Santiago‐Pérez Antonio , Ortiz José Eugenio , Sánchez‐Palencia Yolanda , Saos Thibaud , Grégoire Sophie , Pois Véronique , Vialet Amélie , Monge Guadalupe , Moigne Anne‐Marie , Caparrós Miguel , de Torres Trinidad , Bermúdez de Castro José María , Barroso‐Ruiz Cecilio
Published: December 2022

Objectives

To present a new dental specimen that will provide additional evidence for a better understanding of early European Upper Pleistocene hominin morphological variability.

Materials and Methods

We described the morphology of this human right lower third molar at both the outer enamel surface and the enamel–dentine junction by means of micro‐computed tomography. In order to better understand hominin diversity, our morphological and metrical results were compared with those of other hominins obtained from published research. We provide a direct aspartic acid racemization dating of the molar.

Results

The direct dating (104.3 ka) situates the molar within the Marine isotopic stage 5d. The crown dimensions are comparable to those of the Sima de los Huesos sample and modern humans. The combination of a continuous middle trigonid crest and a well‐developed anterior fovea lies within the range of morphological variation reported for Neanderthal lower molars. The distal portion of the molar has a prominent protostylid.

Discussion

Crown and root morphology of this molar fits within the Neanderthal morphological pattern. However, both its dimensions and the absence of a hypoconulid tend to position this specimen away from contemporaneous Neanderthals and rather relate it more closely to some Middle Pleistocene populations.

Conclusions

A new dental specimen is added to the Iberian Peninsula fossil record from the Marine isotopic stage 5, attesting to some degree of dental variability in the early Upper Pleistocene.
Contextualizing pandemics: Respiratory survivorship before, during, and after the 1918 influenza pandemic in Newfoundland
Authors: van Doren Taylor P. , Kelmelis Saige
Published: December 2022

Background

Research on the 1918 influenza pandemic often focuses exclusively on pandemic years, reducing the potential long‐term insights about the pandemic. It is critical to frame the 1918 pandemic within the underlying population dynamics, health, and sociocultural context to understand what factors contributed to pandemic mortality and survivorship, with respect to observed inequality, and consequences of the pandemic.

Materials & Methods

Individual death records and censuses from The Rooms Provincial Archives and Memorial University of Newfoundland Digital Archives for three major causes of death—influenza and pneumonia; tuberculosis; and pooled bronchitis, measles, and whooping cough—were collected for three periods in the early 20th century: pre‐pandemic (1909–11), pandemic (March 1918–Janaury 1919), and post‐pandemic (1933–1935). We calculated pooled age‐standardized mortality rates and changes in pre‐ to post‐pandemic mortality rates by region. We fit Kaplan–Meier and Cox proportional hazards models to each period, controlling for age, cause of death, and region.

Results

Pandemic mortality was higher than that of pre‐ and post‐pandemic periods. Post‐pandemic mortality was significantly lower than pre‐pandemic mortality in all regions, except Western Newfoundland. Survival was lowest during the pandemic and increased significantly post‐pandemic (p < 0.0001), with no significant differences among regions during the pandemic (p = 0.32). Significant differences in survivorship in 1933–1935 were driven by increasing differences in survivorship for P&I among the regions more than other causes of death.

Discussion

Myopic perspectives of pandemics can obscure our understanding of observed outcomes. Inequalities in respiratory disease mortality are evident in pre‐ and post‐pandemic periods, but these would have been missed in investigations of the pandemic period alone.
Quantitative Single‐Molecule Electrochemiluminescence Bioassay
Authors: Zhu Wenxin , Dong Jinrun , Ruan Guoxiang , Zhou Yuan , Feng Jiandong
Published: December 2022

A single‐molecule electrochemiluminescence bioassay is developed here which allows imaging and direct quantification of single biomolecules. Imaging single biomolecules is realized by localizing the electrochemiluminescence events of the labeled molecules. Such an imaging system allows mapping the spatial distribution of biomolecules with electrochemiluminescence and contains quantitative single‐molecule insights. We further quantify biomolecules by spatiotemporally merging the repeated reactions at one molecule site and then counting the clustered molecules. The proposed single‐molecule electrochemiluminescence bioassay is used to detect carcinoembryonic antigen, showing a limit of detection of 67 attomole concentration which is 10 000 times better than conventional electrochemiluminescence bioassays. This spatial resolution and sensitivity enable single‐molecule electrochemiluminescence bioassay a new toolbox for both specific bioimaging and ultrasensitive quantitative analysis.
Bio‐Inspired Bimetallic Cooperativity Through a Hydrogen Bonding Spacer in CO2 Reduction
Authors: Zhang Chanjuan , Gotico Philipp , Guillot Regis , Dragoe Diana , Leibl Winfried , Halime Zakaria , Aukauloo Ally
Published: December 2022

At the core of carbon monoxide dehydrogenase (CODH) active site two metal ions together with hydrogen bonding scheme from amino acids orchestrate the interconversion between CO2 and CO. We have designed a molecular catalyst implementing a bimetallic iron complex with an embarked second coordination sphere with multi‐point hydrogen‐bonding interactions. We found that, when immobilized on carbon paper electrode, the dinuclear catalyst enhances up to four fold the heterogeneous CO2 reduction to CO in water with an improved selectivity and stability compared to the mononuclear analogue. Interestingly, quasi‐identical catalytic performances are obtained when one of the two iron centers was replaced by a redox inactive Zn metal, questioning the cooperative action of the two metals. Snapshots of X‐ray structures indicate that the two metalloporphyrin units tethered by a urea group is a good compromise between rigidity and flexibility to accommodate CO2 capture, activation, and reduction.
Kupferkatalysierte, hochgradig enantioselektive Addition eines Siliciumnukleophils an 3‐substituierte 2H‐Azirine unter Verwendung eines Si‐B‐Reagenzes
Authors: Zhao Zhi‐Yuan , Cui Ming , Irran Elisabeth , Oestreich Martin
Published: December 2022

3‐Substituierte 2H‐Azirine können als gespannte cyclische Ketimine angesehen werden, und hochgradig enantioselektive Additionsreaktionen von Siliciumnukleophilen an acyclische und auch cyclische Ketimine sind bislang nicht erreicht worden. Die vorliegende Arbeit schließt diese Lücke für jene Azirine mit Hilfe einer kupferkatalysierten Silylierung unter Verwendung eines Silylboronsäureesters als ein latentes Siliciumnukleophil. Die daraus hervorgehenden C‐silylierten, ungeschützten (N−H) Aziridine werden in hohen Ausbeuten und mit hervorragenden Enantioselektivitäten erhalten und können danach ohne nennenswerten Verlust des Enantiomerenüberschusses in nützliche Verbindungen überführt werden.