bluuebunny/crossref_metadata_2025 huggingface dataset:
Monthly Trend Investıgatıon of the Dıscharge of a Stream in Cache County. Utah
Authors:   Osmaniye Korkut Ata University, Engineering Faculty, Civil Engineering Department,, KAYA Yunus Ziya , DEMİRCİ Mustafa ,   Iskenderun Technical University, Eng. Faculty, Civil Engineering Department, VARÇİN Hakan ,   Iskenderun Technical University, Iskenderun/Hatay – TURKEY, TURHAN Evren ,   Adana Alparslan Türkeş Science and Technology University, Civil Engineering department
Published: April 2023

Discharge values of streams are critical for planning the water resources of basins. Discharge values of streams may change due to many reasons such as climatological effects or human-related issues. It is essential to make estimations about the discharge values’ trends for more feasible constructions on streams. In this study, discharge monitoring station records of USGS were used to determine the trends over 50 years. The data set is belonging to the Logan River Above State Dam, Near Logan. UT station and it starts in 1971 and ends in 2020. Traditional Mann Kendall Spearman’s Rho and Sen’s slope statistical tests were used to determine the monthly trends. Additionally, a yearly investigation was performed by using the same statistical approaches. According to the obtained results, any significant trends were not detected in the yearly evaluation. However, in the monthly evaluation trends were detected for August and September.
Analysis of Frequency Trends in Amalgamated Peczely Macro-Synoptic Types (1971-2020) Characterising Continental-Scale Circulation Parallel to the Global Warming
Authors:   ", MIKA János ,   Eszterhazy Karoly Catholic University, Institute of Geography and Environmental Sciences, 3300 Eger Leanyka 6, Hungary", KÁROSSY Csaba ,   ELTE Savaria University Faculty, 9700 Szombathely, Karolyi Gaspar sq. 4, Hungary, LAKATOS László ,   "Eszterhazy Karoly Catholic University, Institute of Geography and Environmental Sciences, 3300 Eger Leanyka 6, Hungary"
Published: April 2023

Macro-synoptic classification, based on spatial fields of sea-level pressure often meet application in applied climatology, weather forecasting and in air-pollution meteorology. One of these classifications was defined by Peczely (1957), establishing 13 original classes influencing actual weather in Hungary. These types, however, are of local concern and not appropriate for diagnostic analysis of continent-scale modification of circulation, related to the on-going global climate change. In the present study, new continent-scale circulation types are defined, based on frequent transition between the original circulation types, two cyclonic (Atlantic and Mediterranean) and two anticyclonic (Northward and Central-Southward) groups are defined, joining 3x3 and 1x4 original circulation types. Frequency trends of these amalgamated circulation types are established in the recent 50 years during which period a monotonical warming trend could be established in the mean near-surface temperature of the Northern Hemisphere. An important feature of these circulation trends is that the significant trends of the amalgamated types are of the same sign in all cases, although the signs of the trends are different for the different amalgamated types. Comparison of these significant 50-year trends with those derived from two 30 years periods, however, this comparison suggests that there is no simple universal relationship between the continent-scale circulation and the hemispherical mean temperature.
The Evolution of the Maximum Extreme Temperatures in the Area of the Romanian Black Sea Coast During 1961 – 2020.
Authors:   University Of Bucharest, Faculty of Geography, PETRESCU Laura Elena
Published: April 2023

The present study investigates the trends in the monthly, seasonal and annual regime of maximum temperatures in the Romanian Black Sea coast area over the last 60 years (1961-2020), using the monthly and annual maximum temperature data provided by five meteorological stations (i.e. Sulina, Sf. Gheorghe-Delta, Gura Portiței, Constanța, Mangalia). Three CLIMPACT extreme temperature indices (i.e. monthly and the annual average of maximum temperatures - TXm, the lowest monthly and annual value of the maximum temperature -TXn, and the highest monthly and annual value of the maximum temperature -TXx) and trends analysis methods (i.e. Mann-Kendall test, Sen’s slope estimator) have been used in the study. The targeted region is under a visible and generalized warming, especially in winter and summer. The estimated warming trends are among the highest at national level. At some stations (i.e. Sulina) spring also emerges as a significant warming season. The highest warming rate is up to 5°C (e.g. Constanța). The observed trends could contribute to an improved understanding for urging adaptation actions in some key sensitive economic sectors directly affected by the recent climate warming (e.g. health, tourism, transport, biodiversity).
Potency of Honje Hutan Flowers (Etlingera Hemisphaerica (Blume) R.M.Sm.) as Alpha-Glucosidase Inhibitor
Authors: Riyanti Soraya , Agustian Nandi , Syam Akhirul Kahfi
Published: April 2023

The Pangandaran people process honje flowers into fresh drinks that are consumed for health. Theforest honje leaf extract provides antidiabetic activity at a dose of 0.39 mg/g BW can reduce bloodglucose levels by 36.16% has been reported. Limited scientific information from honje hutan flowers,it is necessary on its activity as an alpha-glucosidase inhibitor and study its chemical content. Theextraction process was macerated in 70% ethanol for 24 hours and the fractionation process wascarried out by liquid-liquid extraction method with n-hexane, ethyl acetate and water as solvents.Testing the activity of alpha-glucosidase inhibitors colorimetrically using the chromogenic substratep-nitrophenyl α-D-glucopyranoside, alpha-glucosidase enzymes derived from Saccharomycescerevisiae, measurement of absorption at a maximum wavelength of 401.3 nm and acarbose usedas a comparison drug alpha-glucosidase inhibitors. The results showed that the forest honje flowerscontain flavonoids, polyphenols, tannins, quinones, monoterpenoids, and sesquiterpenoids. IC50 valuesfor 70% ethanol extract, n-hexane, ethyl acetate, water and acarbose fractions were 136.79, 307.18,277.12, 66.18, and 14.63 g/mL respectively. The water fraction gave the best inhibitory activity againstalpha-glucosidase with an IC50 value of 66.18 g/mL.Keywords: Etlingera hemisphaerica (Blume) R.M.Sm, honje hutan flowers, alpha-glucosidaseinhibitor.
Antibacterial Activity of Rosemary Oil Against Propionibacterium acnes and The Formulation into Nanoemulsion System
Authors: Priani Sani Ega , F. Nurasyfa Rizza , Eka Darma G.C. , Fitraningsih Sri P. , Syafnir Livia , Prayitno Robby
Published: April 2023

Acne is an inflammatory condition of the pilosebaceous unit that can occur due to infection ofPropionibacterium acnes. Rosemary essential oil contains various active compounds that haveantibacterial activity. Nanoemulsions have been developed as a delivery system to the pilosebaceousunit. This study aimed to determine the antibacterial activity of rosemary oil against P. acnes anddevelop it into a nanoemulsion system. The antibacterial activity was conducted by the agar diffusionmethod. Rosemary oil contains 1,8-cineole as the main active compound and has antibacterial activityagainst P. acnes with an inhibitory zone of 11.315±0.069 mm at a concentration of 4%. Rosemaryoil was successfully developed into a nanoemulsion system using Tween 80 as a surfactant and acombination of ethanol and PEG 400 as a co-surfactant. The rosemary nanoemulsion has a clearphysical appearance with an average globule size of 33.50±0.01 nm and a PDI value of 0.45±0.03. Thepreparation has good physical stability based on centrifugation, heating cooling, and freeze-thaw tests.The study shows that rosemary oil has antibacterial activity against P. acnes and has been successfullydeveloped into nanoemulsion preparations with good characteristics and physical stability. Keywords: Acne vulgaris, Nanoemulsion, Propionibacterium acnes, Rosemary oil.
Transjugular Approach in Catheter Ablation of Ventricular Ectopy Originating from the Superior Tricuspid Annulus: An Effective Alternative to the Unsuccessful Transfemoral Approach
Authors: Cardoso Acácio
Published: April 2023

Ventricular premature complexes originating from the tricuspid valve can be a major challenge for the electrophysiologist. Anatomical features of the tricuspid valve impose limitations for mapping and catheter ablation through the femoral vein (inferior approach). In this case, we report the elimination of a ventricular ectopy by radiofrequency catheter ablation through the transjugular approach after three unsuccessful attempts through the inferior approach.
Implementasi Model Kesuksesan Sistem Informasi DeLone dan McLean pada SVOD Platform (Studi Kasus: Netflix)
Authors: Wicaksana Nico Yonatan , Suroso Jarot Sembodo
Published: April 2023

Abstract — Netflix is a pioneer in the video on demand subscription platform in Indonesia and remains the most popular video streaming service in the world, but Netflix has been forced to relinquish its position as the SVOD provider with the highest subscribers to become the fourth position in Indonesia. The SI DeLone and McLean success model modified by Hudin and Riana in 2016 is used in this study to determine Netflix's success factors and can be used for sustainability progress. The Smart PLS software program was used to evaluate survey data from 410 respondents, which indicated that information quality had a significant effect on system usage (Statistics T=2.85; P-Values=0.005; F-Square=0.023) and user satisfaction ( Statistics T=2.927; P-Values=0.004; F-Square=0.024). However, the quality of the system has no significant effect on system use (T-Statistics=2.628; P-Values=0.009; F-Square=0.018) but has a significant effect on user satisfaction (T-Statistics=5.219; P-Values =0.000; F-Square = 0.086). In addition, service quality has a significant effect on system usage (T-Statistics=3.447; P-Values=0.001; F-Square=0.032) and user satisfaction (T-Statistics=3.654; P-Values=0.000; F-Square = 0.043 ). The use of the system also has a significant effect on net benefits (Statistics T=6.625; P-Values=0.000; F-Square=0.16) and user satisfaction (Statistics-T=7.417; P-Value=0.000; F-Square= 0, 14). The last factor is user satisfaction which has a significant effect on net profit (T-Statistics=6.509; P-Values=0.000; F-Square=0.124). Suggestions for further research are to develop a model with other models to achieve better research results and to find out more independent variables that influence the success rate of the Netflix platform in Indonesia.
Brand Personality as a Determinant of Consumer Loyalty of Mobile Phones and Cars in the Republic of Serbia
Authors: Stanković Jelena , Đukić Suzana
Published: April 2023

Brands that have highly loyal consumers are in the function of the identity and image of their personality. The primary drivers of loyalty to such brands are the intangible characteristics of brands that have a certain symbolic meaning for consumers. In that sense, brands are in the function of articulating consumers as personalities and achieving an appropriate image. To achieve this, brands are often considered individuals who, like consumers who buy them regularly, have similar characteristics. If the characteristics of brands and the characteristics of consumers are more harmonized, consumers will be more loyal. Starting from the above, the aim of the author is to investigate the influence of brand personality dimensions on consumer loyalty to two groups of products: mobile phones and cars. The research was conducted on the territory of the Republic of Serbia. The results of the research are essential for brand management because they represent guidelines for undertaking certain activities in building brands with a leading position in the market.
DEMODECOSIS WITH DERMATITIS DUE TO FUNGAL INFECTION MALASSEZIA SP. IN SHIH TZU DOG: A CASE REPORT
Authors: Ernawati Ni Made , Soma I Gede , Suartha I Nyoman
Published: April 2023

A 10-year-old male Shih Tzu dog named Renbow is experiencing skin problems with signs of itching. Clinical examination showed alopecia, erythema, thickening of the skin and oily skin. On the face to the left side of the neck, the dog was injured due to scratching with a high enough intensity with swelling under the skin filled with fluid. On examination of deep skin scraping on the skin found the mite Demodex sp. amounted to 3-8 per one field of view and skin cytology examination showed the fungus Malassezia sp. with the spores. Hematological examination showed that the animal had normochromic normocytic anemia. The case dog was diagnosed with demodicosis with dermatitis due to fungal infection of Malassezia sp. The therapy given is by cleaning the injured skin using Chlorhexidine and smeared with Gentamicin and Ketoconazole (in the form of an ointment), administering the antiparasitic NexGard SPECTRA®, Clindamycin, Cetirizine, Furosemide and fish oil. Dogs are bathed 2 times a week using a shampoo containing sulfur. Evaluation after 10 days the dog's condition has improved with reduced scratching intensity, swelling due to fluid on the neck and face has disappeared, the erythema has begun to decrease and the initially oily skin has begun to disappear. Examinations deep skin scrapping after 10 days also showed the absence of Demodex sp mites. and reduced findings of Malassezia sp. The treatment given is continued in the next two months to be re-evaluated. Dogs show improvement in condition after being given therapy and intensive care is needed for dogs to prevent re-infection.
Angka Lempeng Total Bakteri dan Jumlah Bakteri Non-Coliform pada Anjing Sehat dan Diare
Authors: Pradipta Indra Manik , Suarjana I Gusti Ketut , Gelgel Ketut Tono Pasek
Published: April 2023

Penelitian ini bertujuan untuk mengetahui angka lempeng total bakteri dan jumlah bakteri non-coliform pada anjing sehat dan diare diisolasi dari feses anjing yang berada di klinik hewan Denpasar dan Badung. Sampel yang digunakan adalah feses segar dari anjing sehat dan diare dengan total keseluruhan 20 sampel (10 sehat dan 10 diare). Metode dari penelitian ini dilakukan dengan mengisolasi bakteri pada media Nutrient Agar menggunakan metode tuang untuk Angka Lempeng Total Bakteri (ALTB) dan media Eosin Methylene Blue Agar menggunakan metode sebar untuk bakteri non-coliform data yang diperoleh di uji dengan menggunakan Uji T Independent. Hasil penelitian menunjukan angka pada anjing sehat sebanyak 3,7 x 107 (CFU/g) untuk ALTB dan 1,5 x 107 (CFU/g) untuk bakteri non-coliform sedangkan pada anjing diare sebanyak 1,5 x 109 (CFU/g) untuk ALTB dan 7,3 x 107 (CFU/g) untuk bakteri non-coliform. Dari hasil penelitian diperoleh kesimpulan ALTB dan jumlah bakteri non-coliform memiliki perbedaan signifikan antara anjing sehat dan diare yang dimana anjing sehat memiliki jumlah koloni bakteri lebih sedikit dibandingkan dengan anjing diare yang memiliki jumlah koloni bakteri lebih banyak (P?0,05). Perlu dilakukan penelitian lebih lanjut terkait dengan pengaruh bakteri non-coliform dari anjing terhadap lingkungan sekitar.
ANALISIS ASUHAN KEPERAWATAN PADA NY. A DAN NY. SJ DENGAN PENERAPAN TERAPI RELAKSASI NAFAS DALAM TERHADAP PENURUNAN TEKANAN DARAH
Authors: Wahidah Alfiatun , Sari Siska Mayang
Published: April 2023

Elderly is someone who has reached the age of 60 years and over which is identified with a period of helplessness and decline. Hypertension is the most common disease suffered by the community, especially in the elderly, because this disease cannot be cured, serious treatment is needed. In addition to pharmacological therapy, non-pharmacological therapy also needs to be carried out in this case modifying lifestyle, reducing sodium intake, reducing stress and avoiding smoking. Non-pharmacological therapy also consists of complementary therapies such as acupuncture, relaxation techniques (deep breathing exercises). The method in scientific work is the analysis of nursing care at PSTW Khusnul Khotimah. Subjects consisted of 2 participants with hypertension problems and the intervention given was deep breathing relaxation therapy. The results of the implementation of deep breathing relaxation therapy which was done once a day for 3 days proved that there was a decrease in blood pressure, with an average decrease in blood pressure in Grandma A aged 67 years, namely systolic blood pressure of 8 mmHg and 8 mmHg diastolic, and in Grandma SJ is 80 years old, systolic blood pressure is 8 mmHg and diastolic is 5 mmHg. The author recommends the nurse as the person in charge of the homestead to continue the implementation of deep breath relaxation therapy once a day with a duration of 15 minutes.
GAMBARAN PERSEPSI MASYARAKAT TERHADAP VAKSIN COVID-19 DI KELURAHAN KALIBENDA KABUPATEN BANJARNEGARA
Authors: Kusumo Kelvin Angling , Handayani Rahmaya Nova , Burhan Asmat
Published: April 2023

Coronavirus 2019 (Covid-19) is the virus responsible for the pandemic in all countries of the world. This disease is caused by the SARS-CoV-2 virus. The Covid-19 fraction of confirmed cases and the death rate is around 2,67 percent. Giving vaccines to the community is one of the prevention methods used to control transmission. This research is quantitative research using descriptive methodology and cross-sectional design. The research was conducted in November 2021 to July 2022 in depth with 147 community members in the Kalibenda Village, Sigaluh District, Banjarnegara Regency using purposive sampling technique and offline questionnaire distribution. Public opinion on Covid-19 immunization is good, which is determined by the achievement of vaccination objectives, vaccine safety, vaccine efficacy, and religious beliefs about vaccination, according to the research findings. This view affects public acceptance of the Covid-19 vaccine. This method of vaccination was rejected because of the bad attitude of society. Based on scientific findings, education can be directed at all categories of respondents who are not ready to get the Covid-19 immunization. Through this educational campaign, it is hoped that the public will be provided with sufficient knowledge and research-based evidence to limit the spread of false information about the Covid-19 vaccination.
Reaksi Usaha Mikro Merespon Insentif Pajak dalam Investasi dan Inovasi
Authors: Kristiana Deranika Ratna , Kristianti Ika Puspita
Published: April 2023

The purpose of this study is to identify micro-entrepreneurs who take advantage of tax incentives and MSME actors who invest in loan instruments to increase their business capital or innovate products to attract public attention for the continuity of their business. This research uses explanatory method; the testing hypothesis is formulated using descriptive qualitative data by distributing online questionnaires to micro-entrepreneurs. The total data taken was 84 respondents. The results of the study show that the reaction of micro-entrepreneurs to government policies in the final PPh has no impact on the product innovation of micro-entrepreneurs and investment in loan instruments for micro-entrepreneurs has an impact on product innovation of MSME actors. The final PPh DTP policy has implications for the reaction of micro-entrepreneurs in addressing this policy. Fiscal policy needs to be disseminated to the public, especially micro businesses. Exploration of the concept of fiscal policy refers to the latest regulations governing the DTP final PPh policy.

Keywords: Fiscal Policy; Tax Incentives; Responds Of Small Enterprises; Loan Instrument Investment; Product Innovation
Mechanical and surface properties of a 3D-printed dental resin reinforced with graphene
Authors:   Universidade Católica Portuguesa, Faculdade de Medicina Dentária, Viseu, Portugal, Salgado Helena , Fialho Joana ,   Escola Superior de Tecnologia e Gestão, Instituto Politécnico de Viseu, Viseu, Portugal, Marques Marco ,   INEGI – Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial, Porto, Portugal, Vaz Mário ,   Universidade do Porto, Faculdade de Engenharia, Porto, Portugal, Figueiral Maria ,   Universidade do Porto, Faculdade de Medicina Dentária, Porto, Portugal, Mesquita Pedro ,   Universidade do Porto, Faculdade de Medicina Dentária, Porto, Portugal
Published: April 2023

Objectives: Commercial photocurable polymers used in dental additive manufacturing still have mechanical limitations. The incorporation of graphene may provide interesting advantages in this field. This study aimed to evaluate in vitro the effect of adding graphene nanoparticles to a 3D-printed polymethylmethacrylate dental resin in terms of surface roughness, flexural properties, and hardness. Methods: A 3D-printed dental resin (Dental Sand, Harz Lab) was loaded with four different graphene nanoplatelet (Graphenest) concentrations: 0.01wt%, 0.1wt%, 0.25wt%, and 0.5wt%. The neat resin was used as the control group. The surface roughness was measured with a contact profilometer using bar-shaped specimens (50x10x4mm). The flexural strength of specimens (80x10x4mm) from each group was calculated using the 3-point bending test in a Universal Test Machine. Hardness shore D was measured using a manual durometer on round-shaped specimens (12x6mm). Data were evaluated using the Kruskall-Wallis test followed by post-hoc Bonferroni corrected pairwise inter-group comparisons. Statistical significance was set at p<0.05. Results: Graphene improved 3D-printed PMMA resin hardness with statistical significance at a concentration of 0.01wt% (p=0.043). Surface roughness increased with graphene concentrations above 0.01wt%, with statistically significant differences at 0.25wt% (p=0.006) and 0.5wt% (p=0.005) concentrations. Flexural properties worsened with increased graphene concentrations, and these differences were significant in the concentrations of 0.25wt% (p=0.028) and 0.5wt% (p=0.006). Conclusions: The use of graphene as a mechanical reinforcement nanomaterial seems to be viable at low concentrations without prejudice to the surface roughness of a 3D-printed polymethylmethacrylate resin.
Komunikasi terapetik konselor dalam pendampingan korban kekerasan seksual pada anak laki-laki
Authors: Wahyuningsih Sri
Published: April 2023

Pada tahun 2020 terdapat kasus kekerasan seksual yang dilakukan pada 25 anak laki-laki di sebuah pesantren di Sidoarjo yang dilakukan oleh Ustaz di pesantren tersebut sejak tahun 2016. UPTD PPA Sidoarjo sebagai badan yang dibentuk Pemerintah Kabupaten Sidoarjo yang bertugas dalam pendampingan perempuan dan anak korban kekerasan seksual di Kabupaten Sidoarjo memiliki peranan besar dalam pendampingan pemulihan trauma yang dialami korban. Salah satu upaya yang digunakan konselor UPTD PPA Sidoarjo dalam proses pendampingan korban adalah komunikasi terapeutik, yang berperan penting dalam penyembuhan korban. Penelitian ini bertujuan untuk mengetahui tahapan, teknik dan hambatan komunikasi terapeutik yang dilakukan oleh koselor dalam proses pendampingan anak laki-laki korban kekerasan seksual. Jenis penelitian menggunakan penelitian kualitatif dengan pendekatan studi kasus. Menggunakan teori interaksi simbolik dan teori self disclosure. Metode pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Informan dipilih dengan menggunakan metode purposive sampling. Teknik analisis data menggunakan teknik analisis data studi kasus Creswell. Teknik keabsahan data menggunakan triangulasi sumber, teori, dan metode. Hasil penelitian menunjukkan terdapat empat tahapan dalam proses komunikasi terapeutik konselor yakni tahap persiapan, perkenalan, pendampingan, dan akhir pendampingan. Teknik komunikasi terapeutik yang dilakukan oleh konselor terdiri dari teknik verbal, teknik nonverbal, dan teknik hiburan atau relaksasi. Pada proses pendampingan, hambatan yang sering ditemui oleh konselor adalah hambatan usia dan pemahaman, hambatan keluarga dan hubungan antara klien dengan pelaku.
Peningkatan Kemampuan Administrasi dan Akuntansi dalam menghitung Biaya Kontrak pada Konsultan Perencana dan Pengawas Konstruksi di Surabaya
Authors: Purwanto Marini , Hemanto Yustinus Budi , Lindrawati
Published: April 2023

Accounting is a practical science in its application in accordance with the specific applications and needs of each type of business entity. This community service activity is designed to provide assistance in preparing CV X's financial reports in the field of construction management consulting services that require progress reports on the progress of each contract. This community service activity is carried out by providing training to administrative staff so they can use Microsoft Excel from templates that have been made and guided by the community service team. Management expects that the output of this accounting information system can evaluate every ongoing project or project that has completed the contractual period. The output of this community service activity from this accounting information system is to accurately calculate the value of the cost of each project so that evaluation of the physical progress of the project and evaluation of the price and profitability analysis of each service contract can be carried out for monitoring and subsequent planning. The following evaluation needs follow-up to evaluate the application of PSAK 34 related to accounting for construction management consulting services.
Comparative study of Riau Pos and the Star Media implementation in convergence continuum
Authors: Yazid Tantri , Salsabila Salsabila
Published: April 2023

In this day, media competition using technologies is competing to provide and reach the reader. Technologies are developing, and every medium has its own way of growing its activities. This study uses a qualitative method with the Continuum Convergence theory belonging to Daily, Demo, Spillman, and the management concept. The subjects in this study are two media companies named Riau Pos and The Star that compared to understand how media has been carrying out the implementation of Continuum Convergence to maintain its existence in the phenomena that occur, as well as see how the management side and compare it with other media implementation. This research found that Riau Pos and The Star have some differences and similarities in their implementation of continuum convergence. Point out how Riau Pos and The Star differ in managing social media and integrating the technologies.
Female photojournalist discrimination during the Covid-19 pandemic in Indonesia
Authors: Sarwono Billy , Yasak Ellen M. , Ajidarma Seno Gumira , Asteria Donna
Published: April 2023

The development of news about Covid-19 that hit almost the entire world, was conveyed massively by the mass media. The work process of journalists in reporting makes them vulnerable to infection. Photojournalists have to rack their brains to keep sending news. During the pandemic, female photojournalists experienced more obstacles and discrimination than before the pandemic. A strong patriarchal system gives rise to gender discrimination in the male-dominated photojournalist profession. This research is qualitative research with a critical paradigm. Researchers want to see the extent of discrimination against three female photojournalists in Indonesia during the pandemic. This research used qualitative methods, with semi-structured interviews, to explore the experiences of female photojournalists during the Covid-19 pandemic. The findings of this study are the existence of double burden gender discrimination, maternal discrimination, and layoff for those who have high salaries (discrimination based on pay) from the media where they work.
The link between communication competence and family communication patterns
Authors: Arindra Fairuza , Wulandari Maulina Pia , Antoni Antoni
Published: April 2023

The quality of the close relationship between parents and children is difficult for parents of children with Autism Spectrum Disorder (ASD). Many parents do not have the communication competence to build strong interaction with autistic children, which causes interaction patterns at home to be inappropriate. This study aims to determine the influence of communication competence on the relationship quality of parents and children, determine the effect of family communication patterns on the relationship quality of parents and children, determine the effect of family communication patterns on relational maintenance behaviour, determine the effect of relational maintenance behaviour on relationship quality of parents and children, determine the role of relational maintenance behaviour as a mediator of the influence between communication competence and family communication patterns on the quality of the relationship between parents and children. This study uses quantitative research methods with survey methods and purposive sampling techniques. The results of the sample (N=202) indicate that communication competence significantly affects the quality of the relationship between parents and children, family communication patterns significantly affect the quality of the relationship between parents and children, family communication patterns significantly affect relational maintenance behaviour, and relational maintenance behaviour significantly affects the relationship on the quality of the relationship between parents and children, and relational maintenance significantly mediates the influence between communication competence and family communication patterns on the quality of the relationship between parents and children.
How did the company respond to reviews on twitter? Es teh indonesia' case
Authors: Agatha Gabrielle , Susilo Daniel , Juliadi Rismi
Published: April 2023

These days, consumers can easily and quickly express their opinions through social media. This has a big impact and need to be responded wisely by the company. At the end of September 2022, PT Esteh Indonesia Makmur issue a subpoena to the account @ghandoyy due to the use of language and criticism which was considered misleading. Researchers want to see the analysis of social networks and network discourse formed through the concept of issue management and reputation on Twitter using applications such as Netlytic, Gephi, Brand24, DNA, and Visone. The network formed shows that there are many actors and discourses involved. Several clusters form a relationship and a higher degree, in which there are dominant actors who are connected to each other. Future research may shed lighter and more expected to analyze deeper to discuss network analysis using different tools and social media.
MENINGKATKAN KETERBUKAAN SISWA MELALUI KONSELING INDIVIDU PERILAKU AITENDING (PTBK DI KELAS IX G SEMESTER GENAP SMP NEGERI 1 DARMARAJA TAHUN PELAJARAN 2021/2022)
Authors: Idaningsih Elis
Published: April 2023

Bimbingan dan Konseling di sekolah bertujuan untuk membantu siswa untuk mengenal pribadinya, mengenal lingkungannya dan merencanakan masa depannya. Siswa dibimbing dan diarahkan untuk menjalani tugas   perkembangan yang harus dilaluinya namun dalam kenyataannya seringkati siswa menemukan berbagai hambatan dan kesulitan. Oleh sebab itu dilakukan kegiatan penelitian ini dengan tujuan untuk membantu siswa dalam mengatasi permasalahannya sehingga siswa lebih percaya diri, lebih kompeten, lebih objektif dan bersikap positif melalui layanan konseling individu perilaku attending. Penelitian ini merupaka Penelitian Tindakan Kelas yang dilakukan dalam 2 siklus. Instrumen yang digunakan adalah lembar observasi dan panduan wawancara. Hasil penelitian menunjukkan bahwa tingkat keberhasilan konseli pada siklus 1 diperoleh hasil 59,29% (predikat Kurang) dan pada akhir pelaksanaan (siklus 2) didapat hasil 71,43% (predikat Baik). Artinya hasil tersebut menunjukkan adanya peningkatan perubahan perilaku konseli dalam upaya meningkatkan keterbukaan dirinya melalui konseling individu perilaku attending.
Advancements in clinical developments in neo/adjuvant drug therapy for resectable melanoma: ASCO Annual Congress – June 2022
Authors: Andreev Dmitry A. , Zavyalov Aleksander A.
Published: April 2023

In the structure of the incidence of skin tumors, melanoma accounts for a relatively smaller percentage, but that disease is associated with higher risk of an adverse outcome compared with many other malignancies.
The study of innovative clinical developments in drug therapy for resectable melanoma, presented at the American Society of Clinical Oncology Annual Meeting June 2022.
The best clinical developments in drug treatment of patients with resectable melanoma were selected for analysis: 1) phase 3 study KEYNOTE-716; 2) PRADO; 3) Neo Trio; 4) SWOG 1512. The presented developments bring extremely promising results for melanoma therapy workflows.
The use of cutting-edge anti-cancer therapeutics acting on various molecular targets drastically improves the tumor response as well as straitens the appearance of treatment-related adverse events.
Spontaneous subdural hematoma concomitant with subarachnoid hemorrhage and intracerebral hemorrhage due to ruptured brain arteriovenous malformation treated with curative embolization
Authors: Soedjono Harris Kristanto , Sani Achmad Firdaus , Ekowahono Joseph , Kurniawan Dedy
Published: April 2023

Introduction:

An arteriovenous malformation (AVM) consists of a tangled cluster of dilated blood vessels forming anomalous communication between arterial and venous systems without capillary bridging. The most likely manifestations of a ruptured AVM are intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), or intraventricular hemorrhage (IVH). Subdural hematoma (SDH) is exceptional in cases of ruptured brain arteriovenous malformation (BAVM).

Case Report:

A 30-year-old female was referred to the Emergency Room with a major complaint of sudden thunderclap headache 1 day before admission. The patient also complained of double vision and left ptosis that lasted for 1 day. There was no other complaint or history of hypertension, diabetes, or trauma. Non-contrast head computed tomography (CT) showed ICH-SAH-SDH on the left side of the brain which was not typical of a hypertensive pattern. The secondary ICH has a score of 6, indicating that 100% of the bleeding might be caused by underlying vascular malformation. Furthermore, cerebral angiography showed cortical plexiform BAVM on the left occipital lobe, and the patient underwent curative embolization.

Discussion:

Spontaneous SDH is very rare, and there are some hypotheses about the reasons for its occurrence. First, brain movement stretches the arachnoid layer that adheres to the AVM, resulting in direct bleeding into subdural space. Second, high-flow pia-arachnoid ruptured blood might extravasate into subdural space. Finally, the ruptured cortical artery that connects the cortex and dura layer (bridging artery) might also cause SDH. Some scoring systems are useful in BAVM, and this study selected endovascular embolization for the patient.

Conclusion:

Brain AVM rupture usually causes ICH, SAH, or IVH. Clinicians must be more aware of spontaneous SDH because it might be caused by a vascular malformation, although it is rare.
Therapeutic response to rituximab in seropositive neuromyelitis optica: Experience from a tertiary care center in South India
Authors: James Joe , Gafoor V. Abdul , Jose James , Smita B. , Balaram Neetha
Published: April 2023

Objectives:

Neuromyelitis optica (NMO) is a severe central nervous system demyelinating disease caused by autoantibodies to anti-aquaporin-4 immunoglobulin-G (AQP4-IgG). Rituximab, a monoclonal antibody targeting CD20 cells, is effective in neuromyelitis optica spectrum disorder (NMOSD) in several observational studies and small randomized controlled trials. However, this includes both AQP4-IgG antibody positive and negative cases. Whether rituximab is more effective in seropositive NMO is unknown. The aim of the study was to determine the efficacy of rituximab in seropositive NMO.

Materials and Methods:

This single-center ambispective study with retrospective data collection and prospective follow-up included patients with NMOSD who were positive for AQP4-Ig-G and treated with rituximab. Efficacy outcomes assessed were annualized relapse rate (ARR), disability progression by expanded disability status scale (EDSS), very good outcome (defined as no relapse and an EDSS ≤3.5), and persistent antibody positivity. Safety was also monitored.

Results:

Between June 2017 and December 2019, 15 AQP4-IgG-positive cases were identified. The mean (± SD) age was 36 ± 17.9 years and 73.3% were females. Transverse myelitis followed by optic neuritis was the most common presentations. Rituximab was initiated after a median period of 19-weeks from the disease onset. The mean number of rituximab doses received was 6.4 ± 2.3. After a mean follow-up duration of 107 ± 74.7 weeks from the first dose of rituximab, ARR significantly reduced from 0.5 ± 0.9 to 0.02 ± 0.08, difference 0.48 ± 0.86 (95% confidence intervals [CI], 0.0009–0.96;P= 0.05). The number of relapses also reduced significantly from 0.6 ± 0.8–0.07 ± 0.26 , a difference of 0.53 ± 0.91 (95% CI, 0.026–1.05;P= 0.041). EDSS also significantly reduced from 5.6 ± 2.5–3.3 ± 2.9 , a difference of 2.23 ± 2.36 (95% CI, 0.93–3.54;P= 0.003). Very good outcome was obtained in 73.3% (11 of 15);P= 0.002. AQP4-IgG remained positive in 66.7% (4 of 6) when repeated after a mean period of 149.5 ± 51.1 weeks after the first dose of rituximab. Neither pre-treatment ARR, EDSS, time to initiate rituximab, the total number of rituximab doses, or time to repeat AQP4-IgG were significantly associated with persistent antibody positivity. No serious adverse events were observed.

Conclusion:

Rituximab exhibited high efficacy and good safety in seropositive NMO. Larger trials in this subgroup are warranted to confirm these findings.
Studi Persoalan Sistem Persamaan Linear dalam Rangkaian Listrik Berbasis Matlab dan OBE
Authors: Ilmi Ulul , Faroh Rifky Aisyatul , Hanifah Ayu Ismi , Mukhoyyaroh Indah
Published: April 2023

Dalam dunia teknik salah satu contoh penggunaan matriks adalah untuk mencari solusi sistem persamaan linear (SPL). Dalam bidang keilmuan yang mempelajari  rangkaian listrik, tidak jarang digunakan matriks untuk menghitung besaran-besaran atau nilai-nilai yang ada di dalam rangkaian listrik. Untuk mempermudah dalam mencari nilai-nilai tersebut  digunakan proses operasi baris elementer (OBE) dan invers matlab serta Eliminasi Gauss berbasis Matlab sehingga akhirnya diperoleh nilai-nilai yang terdapat di dalam rangkaian listrik tersebut. Nilai-nilai tersebut adalah arus listrik.
Biocompatible lysine protecting groups for the chemoenzymatic synthesis of K48/K63 heterotypic and branched ubiquitin chains
Authors: Mikami Toshiki , Majima Sohei , Song Haewon , Bode Jeffrey
Published: April 2023

The elucidation of emerging biological functions of heterotypic and branched ubiquitin (Ub) chains requires new strategies for their preparation with defined length and connectivity. While in vitro enzymatic assembly using expressed E1 activating and E2 conjugating enzymes can deliver homotypic chains, the synthesis of branched chains typically requires extensive mutations of lysines or other sequence modifications. The combination of K48 and K63 biased E2 conjugating enzymes and two new carbamate protecting groups – pyridoxal 5’-phosphate (PLP) cleavable aminobutanamide carbamate (Abac group) and periodate cleavable aminobutanol carbamate (Aboc group) – provides a strategy for the synthesis of heterotypic and branched Ub trimers, tetramers, and pentamers. The Abac- and Aboc-protected lysines are readily prepared and incorporated into synthetic ubiquitin monomers. As these masking groups contain a basic amine, they preserve the overall charge and properties of the Ub structure, facilitating folding and enzymatic conjugations. These protecting groups can be chemoselectively removed from folded Ub chains and monomers with buffered solutions of PLP or NaIO4. Through the incorporation of a cleavable C-terminal His tag on the Ub acceptor, the entire process of chain building, iterative Abac deprotections, and global Aboc cleavage can be conducted on a resin-support, obviating the need for handling and purification of the intermediate oligomers. Simple modulation of the Ub monomers affords various K48/K63 branched chains, including tetramers and pentamers not previously accessible by synthetic or biochemical methods.
On the Automatic Optimization of Lipid Models in the Martini Force Field using SwarmCG
Authors: Empereur-mot Charly , Pedersen Kasper B. , Caruso Cristina , Perrone Mattia , Crippa Martina , Souza Paulo C.T. , Marrink Siewert J. , Pavan Giovanni M.
Published: April 2023

After two decades of continued development of the Martini coarse-grain force field, further refining Martini lipid models has become a demanding task that could benefit from integrative data-driven methods. Here we employ SwarmCG, an automatic multi-objective optimization approach facilitating the development of lipid force fields, to calibrate exclusively the bonded parameters of lipid models in the context of the finely tuned non-bonded interaction matrix available in Martini 3.0.0. We explore two different CG representations of the molecules and evaluate their ability to further enhance the thermodynamic properties of lipid models in Martini simulations. As training set, we simulate at different temperatures in the liquid and gel phases up to 11 homogeneous lamellar bilayers, composed of phosphatidylcholine lipids spanning various tail lengths and degrees of unsaturation. We evaluate improvements a posteriori using additional simulation temperatures and a portion of the phase diagram of a DOPC/DPPC mixture, thereby gaining insights on the ability of putative refined CG representations to further enhance lipid models in Martini.
Features of the Formation and Implementation of Fire-Hazardous Situations in the Ural-Caspian Region in Abnormally Hot and Dry Years
Authors:   Institute of Steppe UB RAS, Pavleychik V. M. , Yazykbayev E. R. ,   Institute of Steppe UB RAS, Sivohip Zh. T. ,   Institute of Steppe UB RAS, Padalko Yu. A. ,   Institute of Steppe UB RAS
Published: April 2023

The results of the analysis of the relationship between meteorological indicators of fire hazard and the actual development of wildfires are presented. The relevance of the study is due to the need to form a reliable understanding of the prerequisites and trends in the development of fires against the background of changes in the regional climate, accompanied by an increase in its anomaly. The main methodological approach to solving the tasks was to identify the features of the occurrence and spread of wildfires in some abnormally hot and dry years observed in the Ural-Caspian region – 2010 and 2021. The data obtained, reflecting the degree of fire danger and the vastness of the spread of fires, were compared with the average long-term (2001-2021) indicators and with longer data series. The study revealed the features of the seasonal development of fires during the firehazardous periods of the years under consideration in the whole region and taking into account its natural-zonal heterogeneity. Despite the fact that the occurrence of fires in general is stochastic in nature, some data indicate a predominantly agricultural nature of fires. Abnormally hot and dry years were not significantly distinguished by the degree of burning of steppe and desert landscapes; the exception was the extensive spread of fires in the forest and forest-steppe lowlands of the Southern Urals in 2021. The absence of statistically significant relationships between the indicators is evidence that weather conditions, although they form fire hazard conditions, are not decisive for their implementation. The occurrence and spread of fires depend on a complex combination and interaction of many natural and anthropogenic factors. In this regard, we believe that the introduction of effective methods of environmental management can minimize the level of pyrogenic impacts on steppe ecosystems, reduce the threat of damage and ensure the safety of the population.
Sustainable aviation fuel from the perspective of long-term sustainability and development
Authors:   University of Žilina, Šajbanová Kristína , Janovec Michal , Zachar Kuchtová Jana
Published: April 2023

The aim of the article is to create a SWOT analysis of the position of sustainable aviation fuels (SAF) as an innovative available product on the aviation fuel market and to evaluate its development and application in the coming years. The motivation for the analysis and subsequent creation of this work is the fact that the topic of sustainable aviation fuels is currently extremely actual and also relevant for the future of air transport, as well as the future of the ecosystem from the point of view of reducing the emission load caused by the emissions of aircraft engines, which have a non-negligible share of the ecological load our planet. Because the combustion process in aircraft engines is the main factor in the creation of emissions, alternative aviation fuels from sustainable sources have been developed in order to reduce them. Thanks to the analysis of the goals of the influential aviation manufacturers, we found that the attention paid to the implementation of sustainable fuel is currently and will be given increased attention in the future. Achieving this goal will be made possible through technological advances and governance adjustments in many companies affecting aviation, from aircraft and fuel manufacturers to institutions dealing with administrative matters affecting aviation.
Management of nursing education in theoretical-practical activities: reflections in the context of the pandemic
Authors: Correa Thais de Fátima Aleixo , Fontes Victoria Malcher Silva , Barros Kely da Silva , Sousa Michele Monteiro , Araújo Lucianne do Socorro Nascimento de , Menegaz Jouhanna do Carmo
Published: April 2023

Objetivo: refletir sobre a meso e a microgestão do ensino de enfermagem para o desenvolvimento de atividades teórico-práticas e estágios supervisionados no contexto da pandemia de COVID-19. Métodos: trata-se de um artigo de cunho reflexivo, sobre o tema da gestão de ensino na enfermagem e suas adaptações frente às atividades teórico-práticas e estágios supervisionados durante a pandemia. Resultados: as adaptações e ações realizadas na meso e microgestão do ensino neste cenário foram cruciais para o âmbito da educação em enfermagem, considerando os principais aspectos modificados nesse contexto, sendo a criação de estruturas para o trabalho remoto, a utilização de atividades de pesquisa para contribuir na compreensão sobre a COVID-19, a pausa e os preparos a mais envolvidos nas atividades práticas. Para isso, os atores dessa gestão enfrentaram desafios como: insegurança ao retorno das atividades presenciais; necessidade de novas competências e habilidades; sobrecarga de serviço dos docentes; e exigência de autonomia dos discentes. Identificou-se que a pandemia afetou a aprendizagem prática dos discentes e deixou uma visão limitada sobre como se dará a condução das lacunas causadas por esse cenário.  Conclusão: apesar dos esforços dos gestores até o momento, compreende-se que esse é um processo inacabado e de constante evolução.