bluuebunny/crossref_metadata_2025 huggingface dataset:
Population pharmacokinetics of meropenem in critically ill patients
Authors: Rančić Aleksandar , Milosavljević Miloš N. , Rosić Nikola , Milovanović Dragan , Folić Marko , Zečević Dejana Ružić , Petrović Nemanja , Čorbić Mirjana Milojević , Dabanović Vera , Janković Slobodan M.
Published: July 2024

Objective

The pharmacokinetics of meropenem are significantly altered in critically ill patients. A population pharmacokinetic study was designed to estimate typical values of meropenem clearance in critically ill patients and evaluate potential factors of influence.

Methods

After meropenem reached a steady state in each patient, two blood samples were taken within the dose interval. The one-compartment pharmacokinetic model based on the data from 101 intensive care unit patients was built using NONMEM software.

Results

Typical values of meropenem clearance and volume of distribution were 3.80 L/h and 3.52 L, respectively. In the final model, meropenem clearance was influenced by serum concentrations of creatinine (CRE), leukocyte count (WBC), hypertension (HTA), and concomitant use of vancomycin (VAN) or colistimethate (COL): CL (L/h) = 5.29 × CRE ^ 0.000001 × WBCs ^ (−0.165) + 0.000001 × HTA + 0.825 × VAN + 1.28 × COL.

Conclusion

In order to achieve effective plasma concentrations of meropenem in critically ill patients, the meropenem dosing regimen should be adjusted according to individual values of drug clearance.
Crystal structure of (5R,6S,E)-5-acetoxy-2-methyl-6-((2aR,3R,5aS,5bS,11aR,12aS)-2a,5a,8,8-tetramethyl-9-oxotetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-3-yl)hept-2-enoic acid, C32H48O5
Authors: Li Ting-Kai , Xiao Li , Wei Peng , Ye Jiang-Hai , Zhao Chen-Liang , He Kang , Zou Juan
Published: July 2024

C32H48O5, orthorhombic, P212121 (no. 19), a = 7.1564(10) Å, b = 17.542(3) Å, c = 23.134(4) Å, V = 2904.2(8) Å3, Z = 4, Rgt
(F) = 0.0555, wRref
(F
2) = 0.1343, T = 273(2) K.
The cocrystal of 2,2′-(hydrazine-1,1-diyl)bis(1H-imidazole-4,5-dicarbonitrile)– methanol (2/3)
Authors: Yuyao Zhang , Bo Wang , Shengping Fan , Yunlu Li
Published: July 2024

C23H20N20O3, monoclinic, C2/c (no. 15), a = 21.738(2) Å, b = 6.0988(9) Å, c = 24.229(3) Å, β = 114.396(4)°, V = 2,925.3(7) Å3, Z = 4, R

gt
(F) = 0.0533, wR

ref
(F
2) = 0.1434, T = 170 K.
Impacts of operating variables in forward roll coating process of viscous hybrid nanofluid
Authors: Abbas Zaheer , Iqbal Sibgha , Khaliq Sabeeh , Rafiq Muhammad Y.
Published: July 2024

Roll coating plays a significant role in various coating industries such as magnetic records, wallpapers, wrapping, adhesive tapes, books and magazines, photographic and plastic films. The thin layer coating of a magnetohydrodynamic (MHD) viscous hybrid nanofluid by passing through the space between two co-rotating rolls has been studied in an isothermal and incompressible analysis. The governing equation of mass and momentum are obtained then dimensionless using lubrication approximation theory (LAT). The velocity, pressure gradient, and pressure distribution are determined by the exact solution. Using Simpson’s (3/8) rule for numerical integration, the complex integral is examined. Important engineering parameters including power and roll separating force delivered by the rolls to the fluid are also estimated numerically. Raising the volume fraction of nanoparticles raises the pressure distribution and pressure gradient while having little effect on the velocity profile. It seems that the magnetic field and hybrid nanofluid, both seem very advantageous for the efficient roll coating process, controlling the separation force, power input, and distance between the attachment and separation point.
Necesidades de capacitación para desarrollar la habilidad emprendedora en agricultores de pequeña escala. El caso de la comunidad de San Pablo Huixtepec, Oaxaca
Authors: Cortés Rodríguez Carlos Alberto , Martínez Gómez Gladys , Romo Lozano José Luis , Schwentesius Rinderman Rita , Sangerman Jarquín Dora María
Published: July 2024

El objetivo de este estudio fue detectar las necesidades de capacitación de los agricultores ubicados en San Pablo Huixtepec, Oaxaca, para fortalecer su habilidad emprendedora mediante el modelo Borich (1980). Esta iniciativa se ha utilizado en el área educativa y en el sector alimentario con base en las necesidades de los participantes. Se hizo un muestreo no probabilístico por conveniencia con información de 30 agricultores interesados en capacitarse. De un listado de 16 temáticas se calcularon las puntuaciones medias de discrepancia ponderada y se clasificaron según su prioridad. Las que obtuvieron mayor puntaje fueron: el uso de las redes para promover productos y servicios (PMDP = 5.13), el manejo de las tecnologías (TIC) para la promoción y desarrollo del producto (PMDP = 4.63) y el reconocimiento de oportunidades para el crecimiento de la unidad productiva (PMDP = 4.62).
Comparison of Muscle Adaptation to Blood Flow-Restricted Versus Traditional Resistance Training in Healthy Adults: A Brief Systematic Review and Meta-analysis
Authors: Mirzayev Javid , Levitt Danielle E.
Published: July 2024

The primary aim of this study was to systematically compare the effectiveness of blood flow restriction training (BFR) versus traditional resistance training (TRT) to improve muscle size in healthy adults. Secondary outcomes were improvements in muscle strength and endurance. We performed a systematic search with meta-analysis. Using predetermined criteria, 541 unique articles were identified through databases and bibliographies. After screening titles, abstracts, and full texts, 20 articles were included in the review. All 20 articles evaluated muscle hypertrophy, 19 evaluated strength, and 1 evaluated endurance in response to BFR and TRT. Data from 10 articles were included in the meta-analysis. In the qualitative analysis, TRT and BFR increased muscle size without differences between conditions for at least 1 hypertrophy outcome in 13 studies, and TRT or BFR differentially improved hypertrophy in 5 studies. TRT and BFR increased strength without differences between conditions for at least 1 outcome in 15 studies, and TRT or BFR differentially improved strength in 9 studies. Results from the meta-analysis indicate no differences in muscle size (ES = 0.045, 95% CI [−0.278 to 0.367]) or strength (ES = −0.149, 95% CI [−0.439 to 0.141]) improvements with BFR versus TRT. Practitioners can implement BFR training to increase muscle size and strength as appropriate, especially for training periods of 8 weeks or longer.
A DEFINIÇÃO TERMINOLÓGICA NA LEGENDAGEM DE SERIADOS
Authors: Esperandio Isabela Beraldi , Finatto Maria José Bocorny
Published: July 2024

RESUMO: A tradução para a legendagem de audiovisuais tem merecido um foco de atenção renovado na área da pesquisa em Tradução, dado o incremento de acesso de filmes pela internet. Ao ocupar o profissional e também o leigo, que traduz legendas por hobby e na condição de fã, a legendagem de séries televisivas norte-americanas tem gerado materiais interessantes para estudo, também no âmbito da Terminologia. Mesmo com o crescente número de séries que usam terminologias específicas como pano de fundo, como as que se ocupam de temas médicos ou jurídicos, ainda não há muitos estudos sobre essa terminologia em tradução. Por outro lado, as séries de ficção fantástica, como as que tratam de mundos vampirescos e de fadas ou de ficção científica, parecem trazer um vocabulário com elementos bastante semelhantes às terminologias “tradicionais”. Assim, comparam-se neste artigo termos e elementos definitórios nesses dois tipos de séries, com vistas ao desenho de uma pesquisa de mestrado.PALAVRAS-CHAVE: Terminologia; Legendagem; Seriados de TV.ABSTRACT: Translation for the subtitling of audiovisual materials has been under a renewed focus of attention in the area of translation research, given the increased access to movies through the internet. By involving the professional translator and also the layman, who translates subtitles for hobby and as a fan, the subtitling of North-American television series has generated interesting materials for studies, also under Terminology. Even with the growing number of series that use specific terminology as background, such as those dealing with medical or legal issues, there are still not many studies on this terminology in translation. On the other hand, the series of fantasy fiction, such as those dealing with vampire and fairy worlds or science fiction, seem to bring a vocabulary with elements quite similar to “traditional” terminologies. Thus, in this article, terms and defining elements are compared in these two types of series, aimed at designing a Master research.KEYWORDS: Terminology; Subtitling; TV Series.
CENOGRAFIA E ETHOS NOS DISCURSOS DE UM PRESIDENTE: O SUJEITO POLÍTICO JAIR BOLSONARO
Authors: Piaia Miquela
Published: July 2024

Este artigo apresenta uma análise da cenografia e ethos de dois pronunciamentos do atual presidente do Brasil, Sr. Jair Messias Bolsonaro. O primeiro discurso ocorreu durante entrevista concedida a jornalistas, no dia 15 de maio de 2019, no qual fala sobre as manifestações, que estavam acontecendo neste dia em várias cidades brasileiras, feitas por estudantes que protestavam contra o corte de investimentos para a educação pública do país. O segundo aborda a mesma temática e ocorreu no dia 29 de maio de 2019, em entrevista concedida ao canal TV Record. O objetivo geral é realizar e descrever um exame do ethos discursivo, da cenografia constituída nos discursos políticos escolhidos para análise, sob a luz dos estudos da semântica global, cenografia e ethos de Dominique Maingueneau (2008a, 2018), e do discurso político de Patrick Charaudeau (2018). A metodologia utilizada é descritiva e bibliográfica, e utiliza os conceitos teóricos para análise do corpus. Evidenciou-se que, mediante o estudo da cenografia construída no contexto de produção dos discursos, é possível realizar a caracterização do ethos discursivo do enunciador, a partir das posições assumidas por ele no cenário político analisado.Palavras-chave: cenografia; ethos; discurso político.
DISCURSO E SUBJETIVIDADE: AS REPERCUSSÕES MIDIÁTICAS SOBRE A DEFESA DE DILMA NO JULGAMENTO DO IMPEACHMENT
Authors: Amaral Abraão Janderson dos Santos , Sousa Raimundo Isidio de
Published: July 2024

Em 2016, durante o julgamento do Impeachment de Dilma Rousseff no Senado, estiveram em evidência várias repercussões midiáticas sobre o discurso de defesa da ex-presidenta, com resquícios simbólicos ancorados nas posições às quais pertenciam os sujeitos midiáticos. Com enfoque nesse acontecimento, este trabalho objetiva analisar a forma como os portais de notícia UOL e Carta Capital se manifestaram subjetiva e discursivamente em suas reportagens. Para tanto, delineou-se as condições de produção do arquivo discursivo; em seguida, interpretou-se as discursivizações e os movimentos subjetivos dos portais de notícia, bem como suas implicações na produção de efeitos de sentidos acerca do impeachment. A fundamentação teórica tem como aparato a Análise Materialista de Discurso, recorrendo-se a autores como Pêcheux (1997; 1999; 2014) e Orlandi (2001; 2017). O estudo é de cunho descritivo-interpretativo e qualitativo. Nas análises, constata-se que os sujeitos produzem suas matérias de acordo com suas formações discursivas, manifestando aspectos subjetivos por meio de marcas discursivas e outros mecanismos textuais. Nesse sentido, o portal de notícias Carta Capital mobiliza discursos inscritos numa formação discursiva favorável à defesa de Dilma, ao contrário da UOL, que aciona uma formação discursiva instituidora de uma imagem negativa da ex-presidenta.
DISCURSO POLÍTICO E OS IMAGINÁRIOS SOBRE O A REFORMA DO ESTADO NA BOLÍVIA (2006-2010)
Authors: Medeiros Leonardo Bacher , Granato Leonardo
Published: July 2024

As transformações do Estado capitalista - tais como a reforma da sua estrutura jurídico-política - trazem consigo elementos de conservação, reprodução e, também, de transformação de certas relações sociais. Essas variáveis se apresentam, ao nível das lutas sociais, por meio de práticas que se manifestam em determinada conjuntura na cena política. Considerando estas premissas, este artigo propõe abordar uma dessas práticas – a do discurso político - na conjuntura da reforma do Estado na Bolívia (2006-2010). A partir desse objetivo, o artigo se dedica a examinar a narrativa acerca dos imaginários sobre o processo de reforma política na cena política boliviana, particularmente, durante o período de ascensão do partido Movimiento al Socialismo (MAS) à institucionalidade estatal. Para esse exame, o artigo fundamenta-se na Análise do Discurso de origem francesa. O material discursivo examinado corresponde a sequências discursivas extraídas das manifestações públicas do vice-presidente Álvaro García Linera, entre 2008 e 2010. Conclui que a narrativa em torno do processo de reforma do Estado no caso boliviano é constituída por um imaginário que se reporta à existência de uma vanguarda indígena na conquista do poder de Estado, além da existência de um horizonte plurinacional de inclusão não apenas dos indígenas, mas também dos demais setores subalternos à institucionalidade estatal, fator que consolida um imaginário de coesão e de unidade nacional na conjuntura de transformação do Estado.
A HISTÓRIA DAS PALAVRAS “JUSTIÇA” E “ANISTIA” E SEUS RESPECTIVOS FUNCIONAMENTOS NO DISCURSO POLÍTICO BRASILEIRO DO SÉCULO XXI
Authors: Petri Verli , Pengo Carla
Published: July 2024

Este trabalho apresenta um recorte da história das palavras “justiça” e “anistia”, baseado em dicionários de Língua Portuguesa e na análise discursiva dos sentidos produzidos por elas quando são transpostas para o discurso político brasileiro, no início do século XXI, no espaço das mídias digitais. Tomamos como base teórica e metodológica a Análise de Discurso de linha francesa em suas relações com a História das Ideias Linguísticas. Os resultados parciais da pesquisa, ainda em andamento, indicam que as palavras sofrem processos de ressignificação em diferentes contextos históricos, políticos e sociais, uma vez em que o sentido é determinado pelas condições de produção do discurso, pela posição ideológica do sujeito e pelo funcionamento da língua. É nesse espaço, sempre em construção, que os sentidos se constituem e é nele que se instalam os analistas de discurso, em um esforço de compreensão.
O MITO, A PÁTRIA AMADA E O INIMIGO: LAMPEJOS FASCISTAS NO DISCURSO ELEITORAL DE 2018
Authors: Paschoal Cristiano Sandim
Published: July 2024

Considerando o recrudescimento de valores intolerantes no espectro sociopolítico do Brasil contemporâneo, o presente artigo tem como objetivo investigar o modo pelo qual a axiologia fascista do inimigo da pátria foi mobilizada pelo discurso da atual extrema direita brasileira nas eleições de 2018. Ancorando-se nos pressupostos teórico-metodológicos bakhtinianos, foram mobilizadas as noções de dialogismo, ideologia e enunciado concreto, tendo como objeto de escrutínio o último programa eleitoral projetado discursivamente pelo candidato representante da extrema direita, Jair Messias Bolsonaro. Visto que o enunciado, sob a ótica dialógico-discursiva, possui como inerência um magnetismo axiológico, durante o movimento analítico, observou-se que o projeto enunciativo do candidato atraiu para sua semântica os valores fascistas de heroísmo e passado mítico nacional, de modo a construir uma noção axiológica envergada de inimigo nacional.
Padre Luiz Sponchiado e a memória da Quarta Colônia
Authors: Manfio Juliana Maria
Published: July 2024

O presente trabalho tem como objetivo compreender como o Centro de Pesquisas Genealógicas (CPG) de Nova Palma-RS se tornou um local de memória da Quarta Colônia de Imigração Italiana. Para tanto, enfocamos não apenas o CPG como depositário de documentos dos imigrantes e seus descendentes, mas também a figura de seu criador, o padre Luiz Sponchiado. Entendemos que a biografia desse sacerdote e pesquisador da genealogia dos imigrantes, para além do seu trabalho religioso e político na região – como incentivador da emancipação política dos antigos núcleos coloniais, por exemplo, tornou-se uma referência do “ser imigrante”, “ser italiano”. Um depositário da memória que constituiu a identidade da região.
Deledda i Zagorka
Authors: Dubravec Labaš Dubravka
Published: July 2024

Grazia Deledda i Marija Jurić Zagorka gotovo su vršnjakinje. Prva se rodila 1871. godine u Nuoru na Sardiniji, a druga 1873. u Negovcu pokraj Vrbovca. Obje su odrasle u provinciji, u dobrostojećim obiteljima, ali bez mogućnosti nastavka školovanja. Međutim, unatoč svemu postale su književnice, koje i desetljećima nakon svoje smrti imaju mnogobrojnu publiku, i uspješno su preskočile prepreke što ih je pred njih postavljala obitelj, društvo, tradicija, ali i sama književna struka i književna kritika. I Deledda i Zagorka napisale su svoje romansirane životopise, preoblikujući sebe u književne likove, Cosimu i Mirjanu. Zagorka je svoj roman objavljivala u nastavcima od 1932. do 1936. godine, dok je Deleddin pronađen u rukopisu nakon njezine smrti 1936. te je objavljen posthumno iste godine, također u nastavcima. Upravo su ta njihova djela mogući ključ razumijevanja poetika ovih dviju geografski udaljenih, ali u mnogočemu sličnih snažnih žena, koje su imale hrabrosti posvetiti svoj život književnosti, kao i promatrati sebe kao književne likove pa se tako poigrati složenim odnosom fikcije i fakcije.
Traduzioni e compilazioni del libro di viaggio di Vialla de Sommières sul Montenegro nelle riviste triestine
Authors: Popović Olivera
Published: July 2024

Sebbene il Voyage historique et politique au Monténégro (1820) di Vialla de Sommières sia stato riconosciuto come una preziosa fonte sul Montenegro dell’inizio dell’Ottocento, le sue traduzioni frammentarie apparse nei periodici italiani coevi rimangono in gran parte inesplorate. Questo studio si propone di colmare tale lacuna indagando le motivazioni alla base della pubblicazione di traduzioni frammentarie del resoconto di viaggio di Vialla nei periodici triestini tra il 1837 e il 1863.
Book Reviews
Authors: Kapetanović Dora
Published: July 2024

Dora KapetanovićUniversity od ZadarTommaseo, Niccolò. 2020. Canti corsi, Annalisa Nesi (a c. di). Milano:Fondazione Pietro Bembo / Ugo Guanda Editore
Analisis Implementasi Kurikulum Merdeka di SMA 1 Kudus (Studi Pada Mata Pelajaran Ekonomi)
Authors: Adella Ahyuni Vinasya , Tri Bowo Santoso Jarot
Published: July 2024

Kurikulum Merdeka adalah kurikulum terbaru dari sistem pendidikan di Indonesia yang diresmikan oleh Menteri Pendidikan dan Kebudayaan. Pembelajaran dengan basis Kurikulum Merdeka di desain agar peserta didik lebih aktif dan pembelajaran terpusat pada peserta didik. Kurikulum Merdeka yang masih baru dalam mengimplementasikannya ini sehingga masih banyak yang harus diperbaiki maka tujuan penelitian ini bertujuan untuk: (1)  untuk mendeskripsikan dan menganalisis implementasi Kurikulum Merdeka di SMA 1 Kudus dan (2) untuk mendeskripsikan konsep pembelajaran ekonomi di kelas berbasis Kurikulum Merdeka di SMA 1 Kudus. Jenis penelitian ini adalah deskriptif dengan menggunakan metode kualitatif. Metode pengumpulan data yang digunakan adalah wawancara, observasi, dan dokumentasi. Analisis data yang digunakan yaitu dengan mengumpulkan data, mereduksi data, kemudian menyajikan data untuk menarik kesimpulan. Hasil penelitian ini menunjukkan bahwa tahap kesiapan SMA 1 Kudus dalam mengimplementasikan Kurikulum Merdeka cenderung berada pada tahap kesiapan mahir dan sudah sesuai dengan arahan dan panduan dari pemerintah, meskipun masih ada kekurangan dalam proses pelaksanaannya. Kemudian, konsep pembelajaran ekonomi di kelas XI yang sudah berbasis Kurikulum Merdeka juga telah dilakukan dengan metode student center learning, akan tetapi dalam pelaksanaan pembelajarannya harus dilakukan pengembangan media pembelajaran di kelas agar lebih bervariasi. Simpulan penelitian ini adalah SMA 1 Kudus sudah cukup baik dalam mengimplementasikan Kurikulum Merdeka meskipun dalam pelaksanaannya harus terus dilakukan perbaikan dalam beberapa aspek.
Feasibility of recycling the filtrate from acidified black liquor for alkaline pulping of golden bamboo grass
Authors: Wang Jin-hui , Zhu Tian , Li Yi-jing , Wang Qian , Ling Yi-kai , Chen Meng-meng , Nong Guang-zai
Published: July 2024

To reduce energy consumption, a new pulping process called A-D-E-RC (acidification/desalination/electrolysis/recycle-cooking) was developed by a research group in Guangxi University of China. The present work focuses on the step of recycle cooking (RC) to further investigate the technical feasibility of A-D-E-RC methods. Golden bamboo grass was considered as fiber source material for pulp, and it was cooked with the acidic treating of wastewater from black liquor. Then, the pulp obtained from each cooking was made into paper to test the changes in its physical properties. As a result, the pulp yield increased from 43.9% to 50.2%, after re-using acidified black liquor, and the paper’s tear index and tensile index were improved. Therefore, this study demonstrated the feasibility of recycle cooking (RC) fiber materials for pulp applied the acidic treating wastewater from black liquor, and thereby, it further identifies the technical feasibility of A-D-E-RC pulping methods.
Sobre as forças moventes das cidades musicais
Authors: Cardoso Filho Jorge
Published: July 2024

Em A Força Movente da Música (2023), Micael Herschmann e Cintia SanMartin Fernandes apresentam um mapeamento da cultura musical de quatro diferentes cidades do estado do Rio de Janeiro, a partir do que denominam "cartografia sensível". Buscamos apontar as características dessa contribuição e possíveis articulações com outras pesquisa no campo das metodologias cartográficas e da sensibilidade em circulação no campo da Comunicação.
A rare Sarmatian coin imitation in lead from a grave at Hódmezővásárhely
Authors: Juhász Lajos
Published: July 2024

The paper discusses a very rare type of Sarmatian coin imitation cast of lead of which only two other specimens are known. The one from Martfű is best preserved, which is very helpful for the interpretation. This piece was found in the grave of a Sarmatian woman in one of the biggest Sarmatian-period cemeteries in the Carpathian Basin, Hódmezővásárhely-Aranyági-halom. The crouched position of the deceased only adds to the peculiarities of the find, since it is very rare for the Sarmatians.
Accuracy of ultrasound TIRADS classification for the differentiation between benign and malignant thyroid lesions taking Bethesda classification as gold standard
Authors: Khan Wajiha Sohail , Farooq Syed Muhammad Yousaf , Nawaz Sadia
Published: July 2024

Background

The TIRADS classification system is commonly used in ultrasound imaging to evaluate the risk of malignancy in thyroid nodules, but there is still debate about its accuracy. The BSRTC categorizes FNA biopsy results to determine the likelihood of malignancy in thyroid nodules, and this remains the gold standard for diagnosis.

Methodology

This is a cross-sectional study design conducted in the Radiology Department of Chughtai Lab Head Office in Lahore. This study assessed 154 patients with thyroid nodules. The ultrasound equipment used for the study is the Toshiba Applio 500 model, while the equipment for FNAC included topical anesthesia, 21-gauge 10 CC syringes, glass slides, cell block, and the Olympus CX23 microscope. The sampling technique employed is the consecutive sampling technique.

Results

Out of 154 patients, the mean age was 42.0 ± 13.6 years. Majority were female (89%) while 11% are male. The P-value of <0.0001 suggests a statistically significant association between TIRADS and Bethesda categories. The findings suggested that ultrasonography is a highly reliable and effective method for diagnosis, with a superior degree of sensitivity and specificity in addition to invasive cytology tests. Results from the ROC curve analysis showed an impressive area under the curve of 0.972. The sonographic features show significant associations with TIRADS categories (P-value <0.0001). The association between TIRADS suspiciousness and Bethesda diagnosis is statistically significant (P-value <0.0001). Benign nodules were most commonly classified as not suspicious (56.5%), followed by mildly suspicious (9.7%), while malignant nodules were primarily classified as highly suspicious (11.0%). Notably, no malignant nodules were categorized as benign.

Conclusion

Healthcare professionals may consider utilizing TIRADS as a first-line imaging method and then BETHESDA if needed to provide patients with the most accurate results and minimize unwanted interventional exposure. Combining these two scoring methods appears to yield the most precise outcomes for identifying and distinguishing benign from malignant nodules, which is critical for arriving at a definitive diagnosis in individuals with thyroid malignancies.
Trial of Memory: Legal Regulation as a Tool of Memory Politics in Contemporary Russia
Authors: Golovashina Oksana V.
Published: July 2024

The article examines how law enforcement sanctions, typically applied to real-life actions, are being transferred to online activities. Building on François Hartog’s ideas, the study links memorial legislation to a new “regime of historicity,” highlighting its unique role in commemoration. By examining relevant laws and media discussions, the study follows the evolution of memorial legislation, demonstrating its importance in commemorating the Great Patriotic War in post-Soviet symbolic politics. Analysis of the amendments to Article 354.1 of Russia’s Criminal Code from its original formulation in 2014 to the revisions in 2021 reveals the shifting legal landscape surrounding online commemorative practices. As virtual spaces are gaining prominence in public discourse and legal interpretations, the boundaries between online activities and real-world actions are becoming increasingly blurred. The key trends in this process include the growing reliance on virtual platforms for information dissemination, the evolving notion of publicity in legal contexts pertaining to online behavior, and the broadening enforcement of Article 354.1. This research sheds light on the intricate interplay between memory politics, virtual spaces, and legal frameworks, reflecting broader societal shifts in information consumption and expression.
Others as Security Threats: Securitizing Discourses, Social Magic, and the Bureaucratic Field
Authors: Grigor'eva Kseniya S.
Published: July 2024

For over 20 years, there has been an ongoing debate about what is primary in the process of securitization—discourses or practices. Traditional research on securitization tends to analyze discourses and practices separately, which can be seen even in studies that attempt to combine these two approaches. In this context, the concept “discourses” refers to a wide range of public political statements, while the concept “practices” mainly refers to the strategies of security professionals. I argue that, in order to gain a better understanding of securitization processes, the research focus should be narrowed to first-order securitizing performatives and the related securitizing practices. This approach will highlight political statements that can genuinely alter social reality, bridge the gap between discourses and practices, facilitate the analysis of institutional mechanisms of securitization, and help obtain much new relevant empirical material. The potential benefits of the proposed approach are illustrated through the analysis of two cases: the Italian case and the Russian case. For the Italian case, the analysis includes declarations of states of emergency related to the exacerbation of the “nomad issue.” For the Russian case, it examines legal acts stipulating the official recognition of migrants as prone to terrorism.
Perbandingan Nilai rSO2 Pra dan Pasca Pembedahan Bedah Kraniotomi Tumor Removal Di RSUP Haji Adam Malik Medan
Authors: Simamora Veronica , Irina Rr. Sinta , Lubis Andriamuri Primaputra
Published: July 2024

Pengukuran regional oxygen saturation (rSO2) menggunakan near- infrared spectroscopy (NIRS) berkorelasi dengan saturasi vena sentral. Oksigen serebral sangat dipengaruhi oleh autoregulasi serebri yang dapat mengatur aliran darah ke otak sehingga menyebabkan oksigen dapat bertambah maupun berkurang. Penelitian ini bertujuan melihat perbandingan nilai rSO2 pre dengan pascabedah kraniotomi tumor removal di RSUP Haji Adam Malik Medan. Penelitian ini merupakan jenis penelitian cohort prospective. Penelitian ini dilakukan pada 12 pasien yang menjalani prosedur pembedahan kraniotomi tumor removal selama 14 April–19 Mei 2023 Sampel dipilih menggunakan metode consecutive sampling. Analisis data menggunakan uji t berpasangan. Sebanyak 12 pasien diteliti rSO2 sebelum operasi kraniotomi didapatkan rerata sebesar 64,50±2,98 pada kanan dan kiri didapatkan rerata sebesar 62,58±3,17. Pada rSO2 setelah operasi kraniotomi didapatkan rerata sebesar 71,58±2,31 pada kanan dan kiri didapatkan rerata sebesar 70,25±3,52. Pada rSO2 kanan rerata sebesar 64,50±1,90 dan rSO2 kanan sesudah penelitian ini didapatkan rerata sebesar 71,58±1,71 dengan nilai p<0,05 secara statistik terdapat perbedaan bermakna antara rSO2 kanan sebelum dan sesudah operasi. Simpulan, terdapat perbedaan antara rSO2 sebelum dan sesudah pembedahan kraniotomi tumor removal di RSUP Haji Adam Malik, Medan.
Terapi Substitusi Ginjal pada Sindrom HELLP ( Hemolysis, Elevated Liver Enzymes and Low Platelets) dan Cedera Ginjal Akut
Authors: Tanto Dedi , Kestriani Nurita Dian
Published: July 2024

Renal replacement therapy (RRT)/terapi substitusi ginjal untuk pasien cedera ginjal akut di unit perawatan intensif menghadirkan masalah unik dalam menyediakan pembuangan biokimia dan cairan pada pasien dengan instabilitas sirkulasi, inotropik, dan peningkatan permeabilitas kapiler. Pasien pre-eklamsia dengan insufisiensi ginjal dapat ditegakkan diagnosisnya jika kadar kreatinin serum lebih atau sama dengan 1,1 mg/dL. Pasien hamil dengan pre-eklamsia berat (PEB) dan sindrom hemolysis, elevated liver enzymes levels and low platelet levels (HELLP) merupakan salah satu faktor risiko cedera ginjal akut pada kehamilan. Peningkatan kreatinin juga dilaporkan meningkatkan progresivitas terjadi strok iskemik Seorang perempuan berusia 21 tahun dengan pascaoperasi sectio caesaria dengan indikasi gawat janin pada pre-eklamsia berat disertai cerebrovascular disease infarct, acute kidney injury dd/acute on chronic kidney disease, asidosis metabolik, elektrolit imbalans, masuk di rawat di ruang rawat intensif RSUP Dr. Hasan Sadikin, Bandung. Pascaoperasi pasien masih dalam keadaan tersedasi dan terintubasi, untuk kemudian dikontrol pernapasannya. Karena terjadi peningkatan kadar kreatinin dan terjadi hiperkalemia refrakter maka pada pasien dilakukan continuous renal replacement therapy. (CRRT). Tujuan CRRT pada pasien ini adalah menekan progresivitas cedera ginjal akut serta hiperkalemia, menghindari fluktuasi hemodinamika, serta menghindari progresivitas cerebrovascular disease (CVD) iskemik.
A breve gestão de Francisco Dornelles no Ministério da Fazenda: O ocaso da hegemonia da FGV-RJ e dos Delfim Boys na formulação da política econômica brasileira.
Authors: ANDRADA ALEXANDRE F. S.
Published: July 2024

RESUMO O texto analisa a gestão de Francisco Dornelles no Ministério da Fazenda em 1985. Além de preencher a lacuna existente na historiografia, reconstrói-se o pensamento e a atuação econômica de Dornelles e Tancredo Neves. Ambos eram conservadores, esposando um diagnóstico “monetarista” sobre a crise brasileira. Esse conservadorismo se traduzia em um relativo continuísmo da política de arrocho implementada por Delfim Netto. Argumenta-se que a saída de Dornelles da Fazenda marca uma importante virada na história econômica do Brasil. FGV-RJ e a ala “delfinista” da FEA-USP perdem a hegemonia sobre a política econômica, abrindo espaço para outras escolas, como Unicamp e PUC-Rio.
Política industrial no Brasil: evidências empíricas em um contexto de mudanças estruturais (2007-2020)
Authors: GIESTEIRA LUÍS FELIPE , CALIARI THIAGO , ORSOLIN-TEIXEIRA FELIPE
Published: July 2024

RESUMO Este trabalho realiza uma análise comparativa do dinamismo econômico e tecnológico dos setores industriais do Brasil durante o período 2007-2020, com vistas a identificar correspondência entre essas variáveis de resultado e a prática de política industrial (PI) setorial. Os resultados sugerem ter havido pouca coordenação entre o emprego dos instrumentos, que a grande parte dos setores não se distinguiu dos padrões gerais da indústria de transformação, que performances excepcionais não estão relacionadas à diversidade de instrumentos, mas que os setores de maior intensidade tecnológica parecem ter respondido particularmente bem à combinação de financiamento do BNDES e da FINEP e uso de poder de compra público.
Fatores sociodemográficos e comportamentais da obesidade: um estudo longitudinal
Authors: Onita Bianca Mitie , Pereira Jaqueline Lopes , Mielke Grégore Iven , Barbosa João Paulo dos Anjos Souza , Fisberg Regina Mara , Florindo Alex Antonio
Published: July 2024

Resumo: O objetivo foi investigar a associação entre fatores sociodemográficos e comportamentais e a ocorrência da obesidade entre 2014 e 2021 em adultos da cidade de São Paulo, Brasil. Realizou-se estudo prospectivo com 1.241 adultos paulistanos, com 18 anos ou mais, participantes da coorte Inquérito de Saúde de São Paulo (ISA) - Atividade Física e Ambiente. O desfecho foi obesidade (sim/não), classificada por meio do índice de massa corporal e com pontos de corte específicos para cada faixa etária. As variáveis de exposição foram: sexo, idade, escolaridade, cor da pele, estado marital, coordenadoria regional de saúde, atividade física nos quatro domínios e comportamentos sedentários. Foram utilizados modelos de regressão logística multinível para a análise longitudinal. Houve aumento significativo de 27,7% na prevalência de obesidade (de 22,6% para 28,9%). Pessoas que praticavam ao menos 150 minutos semanais de atividade física no lazer (OR = 0,44; IC95%: 0,26; 0,76), entre 10 e 150 minutos semanais de atividade física de deslocamento (OR = 0,49; IC95: 0,30; 0,80) e sem companheiro(a) (OR = 0,47; IC95%: 0,28; 0,78) tiveram menos chances de ter obesidade. Pessoas entre 40 e 59 anos (OR = 5,00; IC95%: 2,02; 12,38) e de cor de pele preta (OR = 4,70; IC95%: 1,85; 11,95) apresentaram maiores chances de ter obesidade. O estudo identificou um aumento na prevalência de obesidade durante o período, com aumento nas chances para pessoas de meia idade e cor da pele preta, e diminuição nas chances para pessoas que vivem sem companheiro(a) e para praticantes de atividades físicas no lazer e como forma de deslocamento. Esses resultados podem contribuir para dar suporte a programas e políticas para o controle da obesidade.
Surrounding and background shades effect on color adjustment of single-shade composites
Authors: Santana Márcia Luciana Carregosa , Livi Gabriella de Jess Santos , Santana Tauan Rosa , Silva Paula Fernanda Damasceno , Matos Clara Lemos Leal Barata de , Maciel Carolina Menezes , Faria-e-Silva André Luis
Published: July 2024

Abstract This study evaluated the effects of surrounding and background shades on the color adjustment potential (CAP) and visual color match of two single-shade composites, Vittra APS Unique and Charisma Diamond One. Cylinder-shaped specimens were constructed, consisting of either single-shade composites alone (simple) or composites surrounded by the Forma material at shades A1 or A3 (dual). Simple specimens using only the Forma at the specified shades were also prepared. Color measurements of simple specimens were taken against a gray background using a spectrophotometer. For dual specimens, the color of the inner composite was measured against a gray or chromatic (the same shade as the outer composite) background. Color differences (ΔE00) between the single-shade composites and the A1/A3 composite were calculated. CAP was determined by comparing data from simple and dual specimens. Four experienced dentists scored the color match (perfect to unacceptable) for each specimen using a viewing booth illuminated by an illuminant D65. Data were analyzed with repeated-measures ANOVA and the Kruskal-Wallis test. The results showed that both single-shade composites showed the lowest color discrepancies when they were compared to A1 and A3. Using a chromatic background only significantly affected the CAP when the outer composite was A3. The visual analysis showed poor color matches between the single-shade and control chromatic composites, except for Charisma Diamond One surrounded by A1. In conclusion, the CAP values of the evaluated single-shade composites were impacted by both surrounding shade and background color, and the color match of these materials tended to be poor.
Effect of ultrasonic activation on setting time, pH and calcium ion release, solubility, and chemical structure of calcium silicate sealers
Authors: Scalabrin Simone Argenta , Hashizume Lina Naomi , Weissheimer Theodoro , Só Gabriel Barcelos , Pereira Jefferson Ricardo , Kuga Milton Carlos , Rosa Ricardo Abreu da , Só Marcus Vinicius Reis
Published: July 2024

Abstract This study evaluated the setting time, pH, calcium ion release, solubility, and chemical structure of four calcium silicate sealers after ultrasonic activation (UA). Five sealers were evaluated: Sealer Plus (SP - control); Sealer Plus BC (SPBC), Bio C Sealers (BCS), Endosequence BC Sealer (EBC), and BioRoot RCS (BR). Ten groups were created based on the use or not of ultrasonic activation: SP; SP/UA; SPBC; SPBC/UA; BCS; BCS/UA; EBC; EBC/UA; BR; and BR/UA. Setting time was performed based on ISO 6876:2012 and ASTM C266-07 specifications. Solubility at 24hs, based on ISO 6876:2012. pH and calcium release were evaluated at 1, 24, 72, and 168hs. Raman spectroscopy was used to evaluate structural changes. Quantitative data were analyzed using One-Way ANOVA and Tukey post-hoc test (α=5%). Raman spectroscopy results were qualitatively analyzed. Setting times and solubility of all sealers were not affected by UA (p>0.05). The highest solubility was found for BCS, BCS/UA; and BR, BR/UA (p<0.05). After 24hs, calcium silicate sealers had higher pH than SP and SP/UA (p<0.05). BR and BR/UA had the highest pH at all time points. SP and SP/UA had stable pH at all time points. SP and SP/UA had the lowest calcium release values at all time points (p<0.05). EBC and EBC/UA calcium release significantly differ at 24,72 and 168hs (p<0.05). No chemical changes were observed during Raman spectroscopy. In conclusion, ultrasonic activation affected calcium ion release only for EndoSequence BC Sealer. Ultrasonic activation did not influence the initial and final setting time, solubility, pH, and chemical structure of any investigated sealers.
Dentinal Tubule Occluding Efficacy Of Er: YAG Laser And Universal Adhesive Loaded With Nano-Carbonated Apatite
Authors: Medhat Omnia , Ghieth Mostafa , Elkady Mahmoud , Riad Mona
Published: July 2024

Abstract ER:YAG laser and experimental resin-based dental adhesive loaded with functionalized carbonated apatite filler were used in this study to evaluate the dentin interaction in terms of penetration and occlusion of the dentinal tubules aiding in the control of dentin hypersensitivity (DH). Spheroidal Carbonated apatite nanoparticles (N-CAP), with an average size of 20±5 nm diameter, were synthesized, characterized, and incorporated in a universal adhesive “All Bond Universal, Bisco, USA”, in (2% weight) concentration. Er:YAG laser “Lightwalker, FOTONA, EU” was adjusted to an energy output of 40mJ/ pulse and pulse repetition of 10 Hz for 10 seconds. Dentin specimens were prepared from the buccal surface of 75 extracted sound human molars. The specimens were randomly divided into five groups (n=15) according to the surface treatment: Group (L): Laser only; Group (LB): Laser in combination with adhesive; Group (LBN): Laser in combination with adhesive loaded with N-CAP; Group (B): adhesive only; and Group (BN): adhesive loaded with N-CAP. Depth of penetration and occlusion of the dentinal tubules were assessed using Environmental Scanning Electron Microscope Examination (ESEM). One-way ANOVA was used to compare groups, followed by a pairwise test for multiple comparisons (α=0.05). Groups (LB), and (LBN) showed the highest mean of dentinal tubules’ penetration, with a non-significant difference between them. In contrast, the specimens treated with laser only (L) showed the most minor penetration. The employment of ER-YAG laser irradiation with the adhesive loaded with N-CAP was evaluated to be effective in penetrating and occluding the opened dentinal tubules.
Lactate dehydrogenase activity and total protein as diagnostic markers for cavitary effusions and identification of neoplastic effusions in dogs and cats
Authors: Barbosa Nathália Viana , Silva Rúbia Schallenberger da , Engelmann Ana Martiele , Bonamigo Renata , Mello Camila Benaduce Emanuelli , Andrade Cinthia Melazzo de
Published: July 2024

ABSTRACT: The analysis and classification of cavitary effusions play a crucial role in determining a patient’s diagnosis and prognosis. This prospective study assed ed the activity of Lactate Dehydrogenase (LDH) and the concentration of Total Protein (TP) in serum, pleural, and peritoneal effusions in dogs and cats. Effusions were categorized into three groups: GI (low protein transudate), GII (high protein transudate), and GIII (exudate) following conventional classification. These groups, irrespective of species, were further divided into NPG (neoplastic) and NNG (non-neoplastic) groups. In dogs, significant differences were observed among groups GI, GII, and GIII in terms of effusion LDH activity/serum LDH (LDHR), effusion LDH activity, serum TP/effusion TP (TPR), and effusion TP. Increased LDH activity in effusion was associated with the presence of neoplasia. The groups organized based on the etiopathogenesis of the effusion exhibited varying values of serum TP, TPR, LDHR, effusion TP, and LDH activity in the effusion. Conversely, statistical analysis of the data from cats showed no differences between the groups for the parameters evaluated in this study. Compared to conventional classification, Light’s criteria demonstrated greater sensitivity in distinguishing between transudates and exudates and higher specificity in identifying transudates. We propose the use of established biochemical analyses to discern the mechanism of cavitary effusion formation and advocate for LDH activity measurement in effusions as a complementary diagnostic tool for cavitary neoplasms, especially in cases where cytological analysis of the effusion yields inconclusive results.
Use of 0.25% chlorhexidine nanoemulsion as a skin antiseptic for cats
Authors: Machado Angela Valentina De La Porta , Risso Natalia Horstmann , Lugoch Gabriela , Primaz Sandy Liara , Viana Danilo Augusto Mendes , Vilela Jorge Abrão Pinto , Teixeira Flávia Elizabete Guerra , Stopiglia Cheila Denise Ottonelli , Haas Sandra Elisa , Oliveira Marília Teresa de , Mestieri Maria Lígia de Arruda , Beckmann Diego Vilibaldo
Published: July 2024

ABSTRACT: This study evaluated the antiseptic effect of 0.25% chlorhexidine nanoemulsion (NM-Cl) on cat skin and compare its effect with that of 2.0% chlorhexidine digluconate (CS-Cl). NM-Cl was synthesized using the spontaneous emulsification method, and physical and chemical properties were analyzed. The antiseptic effects of NM-Cl and CS-Cl were randomly tested on the thoracic limbs of 10 healthy male cats. After a wide trichotomy of the thoracic limbs, NM-Cl was randomly applied to the trichotomy area of the right (n = 5) or left (n = 5) thoracic limbs. Then, a catheter was inserted aseptically in the cephalic vein. Subsequently, the same procedure was performed using CS-Cl on the contralateral limb. Cutaneous microbiota swab samples were obtained before antisepsis (Tpre); immediately after antisepsis (Tpost); and 4, 8, and 24 h after antisepsis. The collected samples were immediately inoculated on blood agar plates and incubated at 35 ºC ± 2 ºC in aerobiosis. Colony-forming units (CFUs) were manually counted after 24 h of inoculation. The Kruskal-Wallis and Mann-Whitney U tests were performed between groups and within the same group at different sample times, respectively. The NM-Cl and CS-Cl groups showed a reduction in CFUs between Tpre and Tpost in all animals (P < 0.001). Both formulations presented an antiseptic effect 24 h of antisepsis (P < 0.05), and no difference was observed between formulations at different times (P < 0.05). With a lower concentration of chlorhexidine than CS-Cl, NM-Cl presents effective antiseptic action and prolonged residual effect in antisepsis for cat venipuncture.
Water productivity in irrigated coconut palms in humid tropical climate conditions in eastern Brazilian Amazon
Authors: Carvalho Erika de Oliveira Teixeira de , Fernandes Gabriel Siqueira Tavares , Rua Matheus Lima , Monteiro Adrielle Carvalho , Silva João Vitor Ferreira da , Velame Maria de Lourdes Alcântara , Pinto João Vitor de Novoa , Lins Paulo Manoel Pontes , Miranda Fábio Rodrigues de , Souza Paulo Jorge de Oliveira Ponte de
Published: July 2024

ABSTRACT: The growing demand for coconut water has led to the expansion of irrigated green dwarf coconut cultivation; however, the inefficient use of water has contributed to the degradation and waste of water resources, making fundamental studies aiming to optimize the use of water. The objective of this study was to determine the physical productivity and water productivity of green dwarf coconut palms under the climatic conditions of Santa Izabel do Pará, eastern Amazonia, Brazil. The experiment was carried out from 2020 to 2021, in a green dwarf coconut plantation spaced 7.5 m x 7.5 m in a triangle, at Fazenda Reunidas Sococo, with an area of approximately 7 ha. Water productivity (WP) was determined both in terms of fruit production (WPf) and coconut water production (WPca), through the relationship of fruit productivity (fruit biomass and water volume) with accumulated evapotranspiration. The dwarf coconut tree presented a total production of 105 and 186 fruits plant-1 and 37 and 62 L plant-1 of coconut water in the years 2020 and 2021. The largest volumes of water and the highest weights occurred during the wettest season. WPf was of 1.87 fruits m-3 (2020) and 2.94 fruits m-3 (2021) and WPca 0.66 L m-3 (2020) and 0.98 L m-3 (2021).
Enhancement of oat cereal bars with added Araucaria angustifolia flour: seed, almond or bark
Authors: Castrillon Rafaela Graziele , Marques Caroline , Farias Fabiane Oliveira , Helm Cristiane Vieira , Mathias Alvaro Luiz
Published: July 2024

ABSTRACT: The feasibility of enhancing oat cereal bars, widely recognized for their health benefits, was investigated by replacing up to 5% oats with whole seed, almond, or steam-cooked pinhão husk flour. Pinhão contributes with resistant starch, antioxidant compounds, and minerals. The control oat bar (30.5% of the mixture), without pinhão flours but containing brown sugar (25.5%), raisins (15.0%), glucose (15.0%), coconut oil (3.0%), gelatin (0.5%), and water (10.0%), provides 75.53 kcal, with 15.66% carbohydrates (on a dry basis), 2.88% insoluble fiber, 0.70% soluble fiber, 1.82% protein, 0.62% lipids, and 0.32% minerals. Bars replacing up to 5% of oats with almond, husk, or whole seed flour showed statistically similar compositions, except for lipids, few minerals, phenolic compounds, and antioxidant activity. Concerning daily recommendations, a 22 g bar offers low energy (3.78%, Brasil, 1998) and proportionally high mineral content, including potassium (34.64%), zinc (81.58%), magnesium (108.55%), iron (421.18%), copper (192.98%), calcium (395.13%), and manganese (1,027.00%). Additionally, they exhibit a significant content of total phenolic compounds (8.66 mg GAE/g) and antioxidant capacity (24.43 mg Trolox/g). These innovative bars were well-received in sensory evaluations and demonstrated good commercial potential. Notably, a bar that replaced 5% oats with husk flour could be a viable option for microenterprises due to simplified technology, contributing to waste valorization and encouraging the preservation of the Araucaria Forest.