bluuebunny/crossref_metadata_2025 huggingface dataset:
Relevansi Nilai Tasawuf Sosial di Era Globalisasi Menurut Habib Husein Jafar
Authors: Anwar Khoirul
Published: January 2024

Human life in the era of globalization has become easier and faster. However, this convenience comes with negative impacts, leading to increased individualism, excessive consumption, wastefulness, and the rapid spread of hate speech. To address the complex effects of globalization, social Sufi values are applied by figures such as Habib Husein Jafar Al-Hadar. Habib Husein Jafar, an Islamic scholaractively involved in social media-based preaching, consistently applies a Sufi approach in every aspect of his preaching. This research employs a qualitative research approach using a figure's thought study with a literature review, utilizing content analysis techniques. Data collection involves digital and print documentation related to the theme of social Sufism, with digital documentation from the Jeda Nulis channel and the LogIn program, and printed documentation from books authored by Habib Ja’far. The findings emphasize the significance of applying social Sufi values in this era to cultivate individuals who are pious both ritually and socially. Three social Sufi values identified in Husein Ja’far Al-Hadar's thinking include a minimalist lifestyle, a moderate attitude, and practicing good relations(silaturahmi). Minimalist values teach simplicity, avoidance of the forbidden, and acceptance within one's capacity. Moderate attitude and practicing good relations (silaturahmi) create a life that ensures happiness not only in this world but also in the hereafter, fostering harmonious relationships and preventing individualistic, egoistic, and antagonistic behaviors.
The Meaning of Bhanti-Bhanti as Learning Media for Early Childhood in Wakatobi
Authors: Udu Sumiman , Jumaidin La Ode , Ibrahim Irianto , Marwati Marwati , Susanto Aris
Published: January 2024

The "lunga-lunga" tradition is a custom of putting a baby to sleep by lying on a pillow placed on the shins of the feet while chanting the traditional "bhanti-bhanti" as musical accompaniment. In this "bhanti-bhanti" text, the mother expresses all cultural values to her child. This research used an ethnographic paradigm to explore the education values and the cultural learning from the “bhanti-bhanti’ practiced in Wakatobi. Thus, data collection and processing were carried out using the principles of the ethnographic paradigm. It was found that this tradition is a custom of learning various cultural values that exist in the Wakatobi community. The teaching content consists of moral values, explaining history, and building hope for children. A mother creates sacred texts and simultaneously builds hope about the importance of education, including morals in the family, environment, and social life. Another lesson is to instill the value that "it is better to be hungry than to eat food that is not rightfully yours." Lastly, "bhanti-bhanti" in the "lunga-lunga" tradition teaches cultural values that can contribute to the formation of children from an early age.

Tradisi “lunga-lunga” merupakan pranata menidurkan bayi dengan cara berbaring di atas bantal yang diletakkan di atas tulang kering kaki sambil melantunkan lagu adat “bhanti-bhanti” sebagai musik pengiringnya. Dalam teks “bhanti-bhanti” ini, ibu mengungkapkan segala nilai budaya kepada anaknya. Penelitian ini menggunakan paradigma etnografi untuk mengulas nilai Pendidikan dan pembelajaran budaya dari “bhanti-bhanti” yang diterapkan di Wakatobi. Dengan demikian pengumpulan dan pengolahan data dilakukan dengan menggunakan prinsip paradigma etnografi. Diketahui bahwa tradisi “lunga-lunga” merupakan tradisi pembelajaran berbagai nilai budaya yang ada pada masyarakat Wakatobi. Isi pengajarannya terdiri dari nilai-nilai moral, menjelaskan sejarah, dan membangun harapan bagi anak. Seorang ibu menciptakan teks-teks suci dalam waktu dan ruang yang sama, membangun harapan akan pentingnya pendidikan, termasuk akhlak dalam keluarga, lingkungan, dan kehidupan bermasyarakat. Hikmah lainnya adalah dengan menanamkan nilai bahwa “lebih baik lapar daripada makan makanan yang bukan haknya”. Terakhir, “bhanti-bhanti” dalam tradisi “lunga-lunga” mengajarkan nilai-nilai budaya yang dapat memberikan kontribusi dalam pembentukan anak sejak dini.
Serum Fetuin B Levels and Factors Influencing its Concentrations in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Authors: Chen Shuchun
Published: January 2024

The objective of this study is to explore the serum fetuin B levels and factors influencing its concentrations in patients with newly diagnosed type 2 diabetes mellitus (T2DM) and to provide evidence for the prevention of T2DM and its complications. Two hundred three patients with newly diagnosed type 2 diabetes and 209 healthy controls were recruited. The serum fetuin B levels were measured using an ELISA, and the correlations between fetuin B levels and glycosylated hemoglobin levels, insulin resistance index (HOMA-IR), SOD levels, GSH-PX levels, MDA levels, nonalcoholic fatty liver disease and carotid atherosclerosis were analyzed. We obtained the following results: (1) A significantly higher serum fetuin B level was observed in the T2DM group than in the CON group (P < 0.001). (2) The serum fetuin B level positively correlated with the HOMA-IR, HbA1c, TG, APOB, and GSH-PX levels, but it negatively correlated with HDL-C and SOD levels. The multivariate linear stepwise regression analysis showed that HBA1c was an important factor influencing fetuin B levels. (3) According to the logistic regression analysis, fetuin B is a risk factor for T2DM. Finally, we drew several conclusions: 1. The influencing factors for type 2 diabetes mellitus and non-alcoholic fatty liver disease include increased the serum fetuin B level in patients with newly diagnosed type 2 diabetes mellitus and resulted in a much higher serum fetuin B level in the group complicated with NAFLD. 2. The glycosylated hemoglobin level is an important factor influencing fetuin B levels..
Neolamarckia Cadamba: A Comprehensive Pharmacological
Authors: Verma Rubi
Published: January 2024

Neolamarkia cadamba is one of such Ayurvedic remedy that has been mentioned in many Indian medicinal kinds of literatures. This review discusses about the medicinal values of Neolamarkia cadamba. Herbalism is use of plants for medicinal purposes. Herbalism, also known as phytotherapy is the use of plants to treat common ailments promotes wellness. It is the oldest from of medicinal healing known to man. We reviewed the Pharmacognostical & physicochemical study of Neolamarkia cadamba and its application in the treatment of various ailments like diabetes mellitus, diarrhoea, fever, inflammation, cough, vomiting, wounds, ulcers and antimicrobial activity. Thus, the review will give an onset for the researchers to explore the plants for its medicinal value.
Total Quality Management and Perceived Service Quality: The Impact on Customer Satisfaction and Loyalty
Authors: Ha Nguyen Thi Le
Published: January 2024

Total quality management and perceived service quality are core factors to increase consumer satisfaction and loyalty. Our study examines the relationship between total quality management (TQM) and perceived service quality (PSQ) on customer satisfaction and loyalty. A structured questionnaire was carried out at the National Cancer Hospital in Viet Nam, delivering for inpatients who were treated during April 2018. The data were analysed by using the Statistical Package of Social Sciences (SPSS) 25.0 software and AMOS 25.0 software. A confirmatory factor analysis was assessed to the research model before when used the structural equation modelling test for the proposed hypotheses. Results showed that PSQ has a direct effect on satisfaction and loyalty while the TQM influences loyalty through satisfaction plays as a mediating factor. Our findings reveal that PSQ is a factor related to satisfaction and loyalty. While total quality management has a positive influence on satisfaction but doesn’t have related to a direct effect on loyalty. Our study has practice implications for providers and policymakers when considers factors that aim to increase customer satisfaction and retain loyalty. In addition, service firms should focus on satisfaction factors to improve service quality and maintain loyalty.
Detection and Characterization of an Unknown Impurity in Levothyroxine Sodium Tablets by UHPLC, LC/MS, MS/MS and MS/MS/MS
Authors: Halamoğlu Zeynep
Published: January 2024

Impurities in the active ingredient of a drug are very important for the quality and reliability of the finished product. Therefore, the identification of these impurities constitutes reliability for patients using the drug. Levothyroxine sodium has known but also unknown impurities. Liothyronine sodium is known as the most common impurity of Levothyroxine sodium. Thought to be more active than levothyroxine and with a rapid (few hours) onset and short duration of action, liothyronine sodium is used in the treatment of hypothyroidism, particularly in the cases of hypothyroid coma. In our study, besides known impurities of Levothyroxine sodium, some unknown impurities were observed in samples that were exposed to heat. In these unknown impurities, the most important one that increases the fastest with the temperature that will affect the quality of the product is the impurity at RRT 0.6, according to our impurity method which was developed in-house. The impurity that increases with temperature has been defined by various identification studies, including MS/MS analysis, LC-UV detection etc. The degradation product, which was initially characterized by its retention time as RRT 0.6, was subsequently identified to be a lactose adduct of Levothyroxine API, which is formed by a Maillard reaction between Levothyroxine and lactose.
Preclinical Studies with Digitalis Lanata: A Bibliographic Review
Authors: Soraya Katine Garcia Metz
Published: January 2024

Popular knowledge has always served as a guide for scientific medical study. For over 200 years, the plant known as foxglove has contributed to the treatment of cardiac pathologies. This plant contains more than 80 cardenolide compounds, with digitalis glycosides being the main ones. Even with unquestionable benefits, its use has always been surrounded by care due to its high toxicity, even at low concentrations, requiring researchers to carry out preclinical studies to prove safe doses. In this sense, the present work aims to carry out a bibliographical review in order to compile works that present pre-clinical studies using the active principal digoxin, seeking to understand the procedures carried out by the researchers and the results obtained in their studies. This is a literature review article whose research was carried out in August 2021 and covered the areas of botany, pharmacognosy, biology and pharmaceutical sciences. Databases such as SciELO, PubMed and Academic Google were used, which provided more than 28,000 works. After passing the inclusion and exclusion criteria, four articles were selected, summarized, and compared. Of these, two studies presented the assessment of digoxin in cardiac pathologies, with results confirming the dosages and treatment times previously stipulated for the drug. The other two selected works present new perspectives for the use of drugs already available on the market containing digoxin for the treatment of visceral leishmaniasis and for fighting inflammation in the liver and cancer, respectively. Thus, the highlighted works demonstrate that the use of animal models to carry out tests with digoxin helps in studies to prove the drug’s safety and efficacy in cardiac pathologies. On the other hand, they also significantly contribute to the medical profession, patients, and the pharmaceutical industry by increasing the possibility of treating other already known pathologies, with a focus on improving existing treatments.
XRD Analysis for Characterization of Green Nanoparticles: A Mini Review
Authors: Kumar Manoj
Published: January 2024

Plants are one of the richest sources of biomolecules on earth. In the last decade there has been an increasing interest of researchers and scientists on exploration of antimicrobial and medicinal properties of plants. It is with entry and amalgamation of nanotechnology with phytochemistry, which opened new dimensions. Synthesis of metallic nanoparticles mediated by plant extracts emerged rapidly and had significant explorations. The synthesized metallic nanoparticles are characterized for their size, shape and stability using several techniques such as UV-Visible spectrophotometer (UV-Vis), Fourier Transform Infrared (FTIR), Scanning Electron Microsope (SEM), Dynamic light scattering analysis (DLS). X-ray diffraction (XRD) analysis of nanoparticles is a comparatively new entry in this list. X-ray diffraction analysis provides concrete information regarding structure and crystalline size of nanoparticles, and it can play pivotal role in characterization of nanoparticles.
Temuan Kejadian Penyakit Tetelo pada Kadaver Unggas yang Dikirim ke Laboratorium Patologi Fakultas Kedokteran Hewan Universitas Syiah Kuala
Authors: Etriwati Etriwati , Salim Muhammad Nur , Balqis Ummu , Aisyah Siti , Nazaruddin Nazaruddin , Amiruddin Amiruddin , Rusli Rusli , Hayati Divina Dinda
Published: January 2024

Penyakit tetelo (Newcastle disease) merupakan penyakit penting yang sangat mudah menular dan menyebabkan kematian tinggi pada unggas rentan. Penelitian ini bertujuan untuk mengetahui kejadian penyakit tetelo pada unggas yang dinekropsi di Laboratorium Patologi, Fakultas Kedokteran Hewan (FKH), Universitas Syiah Kuala (USK), Banda Aceh. Sampel penelitian dikoleksi dari 239 ekor cadaver unggas terdiri dari ayam pedaging/broiler, ayam petelur/layer, ayam kampung/buras dan unggas lainnya yang dinekropsi di Laboratorium Patologi FKH USK periode Juli sampai November 2019. Sampel yang dikoleksi yaitu trakhea, proventrikulus, seka tonsil dan otak. Sampel dipilih berdasarkan perubahan patologi anatomi diduga penyakit tetelo, selanjutnya dibuat sediaan histopatologi dan imunohistokimia dalam parafin blok. Hasil penelitian menunjukkan bahwa unggas yang dinekropsi dan mati akibat penyakit tetelo sebanyak 106 ekor, diduga fowl cholera 52 ekor, infectious bronchitis 25 ekor, avian influenza 22 ekor, colibacillosis 14 ekor, chronic respiratory disease 7 ekor, coccidiosis 5 ekor, infectious laryngotrcheitis 4 ekor, infectious bursal disease 2 ekor dan coryza 2 ekor. Simpulan dari penelitian ini bahwa cadaver unggas yang di nekropsi di Laboratorium Patologi FKH USK periode Juli sampai November 2019 sebanyak 44,4% (106/239) terdiagnosa mati akibat terinfeksi penyakit tetelo.
Penggantian Konsentrat Komersial dengan 12% Konsentrat Limbah Closed House Membuat Performa dan Profil Hematologi Babi Tetap Optimal
Authors: Ariana I Nyoman Tirta , Ardana Ida Bagus Komang , Warmadewi Dewa Ayu , Putri Budi Rahayu Tanama , Miwada I Nyoman Sumerta
Published: January 2024

Tujuan penelitian adalah untuk mengetahui efek substitusi konsentrat komersial CP-152 dengan konsentrat asal limbah closed house (KLCH) pada ransum terhadap performa dan profil hematologi babi Landrace. Rancangan penelitian adalah rancangan acak lengkap (RAL) dengan tiga perlakuan dan setiap perlakuan terdirri atas empat ulangan. Perlakuan tersebut yaitu, A: penggunaan 0% KLCH + 24% konsentrat CP-152; B: 12% KLCH + 12% konsentrat CP-152 dan C: 24% KLCH + 0% konsentrat CP-152. Penelitian menggunakan 12 ekor babi Landrace fase finisher dengan rataan bobot badan 63,42 ± 2,39 kg. Parameter penelitian adalah performa dan profil hematologi babi Landrace. Hasil penelitiannya adalah, pada kelompok perlakuan A dan B diperoleh hasil yang tidak berbeda nyata untuk semua parameter penunjang performa (P>0,05). Dengan pemakaian 24% KLCH (perlakuan C) didapatkan performa pertambahan bobot badan harian: 11,5% lebih rendah dan susut bobot badan 35,7% lebih tinggi dibandingkan dengan A dan B (P<0,05). Pemakaian konsentrat komersial 12%-24% KLCH tidak menyebabkan perubahan profil hematologi babi landrace (P>0,05). Simpulan dari penelitian ini adalah substitusi 12% KLCH (B) diperoleh performa yang paling baik. Substitusi konsentrat komersial CP-152 dengan KLCH tidak mengubah profil hematologi babi landrace.
Hypercholesterolemia and its Management UsingVarious Bioactive Compounds: A Literature Review
Authors: Wresdiyati Tutik , Rizaldi Dimas Ahmad , Purnawan Trioso
Published: January 2024

Hypercholesterolemia is characterized by levels of total cholesterol and low-density lipoprotein (LDL) above normal. Hypercholesterolemia is a major risk factor for cardiovascular disease. This study was aimed to explore and analyze various bioactive compounds to manage hypercholesterolemia. Efforts to overcome the condition of hypercholesterolemia are to reduce the consumption of a diet rich in cholesterol and calories, and consuming contemporary hypercholesterolemic drugs such as statins, as well as by regulating the body’s cholesterol metabolism with various antihypercholesterolemic bioactive compounds. Various findings of antihypercholesterolemic bioactive compounds have various sources and effects on cholesterol profiles. Bioactive compounds can be classified according to their mechanism of hypocholesterolemic action, which are inhibition of cholesterol absorption, inhibition of cholesterol biosynthesis, increased cholesterol excretion, increased cholesterol reverse transport, and increased cholesterol catabolism. Several bioactive compounds are involved in a dual mechanism. The development of these various bioactive compounds can be used as an alternative treatment for hypercholesterolemia since contemporary medicines have proven to have many side effects.
Formação continuada docente na perspectiva da educação inclusiva
Authors: Kort-Kamp Thauana Gomes , Azevedo Breno Fabrício Terra
Published: January 2024

The purpose of this article is to analyze the results from the application of the educational product, continuing education course, in the distance modality, called: Introduction to Inclusion and Pedagogical Accessibility. The educational product is linked to the dissertation developed under the Graduate Program in Professional and Technological Education – ProfEPT. The methodological path of this study used the qualitative approach. Regarding the nature and objectives, it is classified as an applied research, of an exploratory and descriptive nature, using the procedures of bibliographic and documentary research. Fifteen teachers were certified, through the Reference Center for Technology, Information and Communication in Education of IFFluminense, for their participation in the Introduction to Inclusion and Pedagogical Accessibility course. The results of the bibliographic and documentary research obtained from the application of data collection instruments corroborated the need for actions aimed at continuing teacher education, with a view to the implementation of an inclusive education.
Commentary on “Marginalisation and Human Rights in Southeast Asia” by Routledge
Authors: Sahrasad Herdi
Published: January 2024

Human rights and democracy in Southeast Asia continues to attract the attention of scientists in this region to study and examine them in depth. In this context, a centralized and methodical style of authoritarianism, such as that used by Suharto's New Order in Indonesia, has restricted public dialogue of human rights and democracy , and is unlikely to attract the public of Southeast  Asia today, according to social scientists, researchers, and Islamic scholars (ulemas). The people of Southeast Asia are tireless champions of human rights, social justice, and democracy to this day. The editors of this book,  namely Al Khanif and Khoo Ying Hooi, have put together a book that, in its own way, succinctly and forcefully analyzes marginalization and human rights in Southeast Asia and provides a range of perspectives on the subject. This book covers a wide range of topics, including the success of ASEAN cooperation in ending statelessness, human rights violations committed against migrant workers, the protection of disabled people's rights on a regional scale, the Rohingya refugee crisis, the Moro's plight, religious and ethnic minorities' rights, academic freedom in authoritarian regimes, child abuse, and security concerns in Southeast Asia.
Keywords: Southeast Asia, Human Rights
Contribution to spider fauna (Arachnida: Araneae) from Bjeshkët e Nemuna mountains (Kosovo)
Authors:   Department of Biology, Faculty of Mathematics and Natural Sciences, University of Prishtina, Mother Teresa street p.n., 10000 Prishtina, Republic of Kosovo, Geci Donard , Naumova Maria ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Tsar Osvoboditel Blvd., 1000 Sofia, Bulgaria, Ibrahimi Halil ,   Department of Biology, Faculty of Mathematics and Natural Sciences, University of Prishtina, Mother Teresa street p.n., 10000 Prishtina, Republic of Kosovo, Grapci-Kotori Linda ,   Department of Biology, Faculty of Mathematics and Natural Sciences, University of Prishtina, Mother Teresa street p.n., 10000 Prishtina, Republic of Kosovo, Gashi Agim ,   Department of Biology, Faculty of Mathematics and Natural Sciences, University of Prishtina, Mother Teresa street p.n., 10000 Prishtina, Republic of Kosovo, Bilalli Astrit ,   University of Peja “Haxhi Zeka”, Faculty of Agribusiness, Street “UÇK” 30000 Pejë, Republic of Kosovo, Musliu Milaim ,   University of Peja “Haxhi Zeka”, Faculty of Agribusiness, Street “UÇK” 30000 Pejë, Republic of Kosovo
Published: January 2024

Since Kosovo is the least explored territory in the Balkan Peninsula when it comes to the study of spider fauna, with large, untouched areas, we aim to explore it in detail. From Bjeshkët e Nemuna Mountains only 15 species have been reported. We collected and identified 323 spider specimens (88♂♂, 235♀♀) from April 2018 to August 2021 at 20 sites in Bjeshkët e Nemuna National Park between 529 and 2066 m a.s.l. These specimens belong to 91 species, 65 genera, and 23 families. Of these, 42 species, 13 genera, and 2 families are new records for the spider fauna of Kosovo, and 90 species are new for the mountains. As a result of our research, the list of species known from the studied region increased from 15 to 105 and the number of known spiders in Kosovo increased to 248 species.
Adaptive neural control for delayed discrete-time switched systems under deception attacks
Authors: Zhao Dongke , Tian Yongjie , Zhao Ning
Published: January 2024

This paper focuses on the issue of adaptive neural control for discrete-time switched systems with time delay and deception attacks. Firstly, the switching signal is constrained by the dwell time. Considering that the deception attacks are unknown, the neural network technique is employed to approximate the attack signals. Then, an adaptive state feedback controller is established to compensate for the adverse effects of deception attacks for switched systems. Meanwhile, sufficient conditions for the boundedness of the switched system are given through the Lyapunov functional method, and the controller gains can be obtained by resolving the linear matrix inequality. Finally, the feasibility of the proposed method is illustrated via a numerical example.
Impact of hypoxia on the molecular content of glioblastoma-derived exosomes
Authors: Di Giulio Simona , Carata Elisabetta , Muci Marco , Mariano Stefania , Panzarini Elisa
Published: January 2024

Hypoxia is a pathologic condition characterized by a tissue oxygen deficiency due to either decreased oxygen intake from outside and/or disruption of oxygen utilization in cells. This condition may arise when the oxygen demand exceeds its supply or the partial pressure of oxygen is below 10 mmHg. This situation poses a significant problem for glioblastoma (GBM) patients as it can activate angiogenesis, increase invasiveness and metastatic risk, prolong tumor survival, and suppress anti-tumor immunity, making hypoxic cells resistant to radiotherapy and chemotherapy. Low oxygen levels in tumors can cause severe cellular changes that can affect the release of extracellular vesicles (EVs), especially exosomes (EXOs), altering their proteomic profile both qualitatively and quantitatively. EXOs represent an adaptive response to hypoxic stress; therefore, they can be used to determine oxygen levels in cancer and assess its aggressiveness. They not only release signaling molecules to attract cells that promote the formation of small vessel walls but also send signals to other tumor cells that trigger their migration, which in turn plays a crucial role in the formation of metastases under hypoxia. This review investigates how the molecular profile of GBM-derived exosomes changes under hypoxic conditions, offering future possibilities for noninvasive diagnosis and monitoring of brain tumor patients.
Assessment of Economic Policy in 2022
Authors: Aukutsionek S.
Published: January 2024

The article describes how the managers of Russia’s industrial and agricultural enterprises (the Russian Economic Barometer’s respondents) assessed in 2022 the governmental economic policy. The author presents the data on the proportion of managers who understand and approve of this policy and on the first-priority measures that they consider necessary to stimulate production.
Mainstreaming technical competences in professional projective capacity, within integration of Bachelor's and Master's degrees in Architecture training to professional itinerary = Integración del Grado y Máster en Arquitectura en un itinerario a la profesión mediante la inclusión de competencias técnicas de capacidad proyectiva profesional
Authors: López-Arquillo Juan Diego , Pereira-Teixeira-de-Oliveira Cristina , Cadenas-Borges María
Published: January 2024

La metodología IPBL está orientada según una actuación realista que sitúa al estudiante en un proceso en condiciones similares a las que se va a enfrentar en un encargo profesional real. Desde el curso 2020-2021, la Escuela de Arquitectura de la Universidad Europea de Canarias se enfrenta a una serie de retos globales propuestos por diferentes organismos, retos dentro de los cuales se integran diferentes asignaturas de todas las áreas de conocimiento de la Arquitectura. Integrando en un proyecto global el desarrollo de las competencias profesionales completas en Arquitectura -aquellas necesarias para desarrollar un proyecto básico y de ejecución- en asignaturas del Grado en Fundamentos de la Arquitectura y del Máster en Arquitectura. Para ello, se han distribuido a través de diversas asignaturas conectadas entre el grado y el máster, potenciando la adquisición de competencias profesionales y competencias personales. La integración técnica de ambas titulaciones desde la capacidad documental profesional del proyecto básico y de ejecución ha sido estudiada por comparación directa tanto en secuencia temporal de implantación, con notables mejoras de calidad documental técnica, autopercepción y capacidad de respuesta intuitiva a proyecto.AbstractIPBL methodology is based on a realistic approach that places students in a process in conditions similar to those they will face in a real professional assignment. From the academic year 2020-2021, the School of Architecture of the UEC is facing a series of global challenges proposed by different organisations, challenges within which different subjects from all areas of knowledge of Architecture are integrated. Integrating the multiple challenges demanded by project-based learning, the development of the complete professional competences in Architecture -those necessary to develop a basic Architectural Project and its execution- in subjects of the Bachelor's Degree in Foundations of Architecture and the Master's Degree in Architecture have been distributed through different subjects connected between the Bachelor's Degree and the Master's Degree, promoting the acquisition of professional and personal competences. The technical integration of both degrees from the professional documentary capacity of the basic and execution project has been studied by direct comparison both in time sequence of implementation, with notable improvements in technical documentary quality, self-perception and intuitive response capacity to the project.
Application of Surface-Stress Driven Model for Higher Vibrations Modes of Functionally Graded Nanobeams
Authors: Lovisi Giuseppe , Feo Luciano , Lambiase Annavirginia , Penna And Rosa
Published: January 2024

This manuscript employs a surface stress-driven nonlocal model to explore the combined effects of long-range interaction and surface energy on higher vibration modes of functionally graded nanobeams. The nanobeam theory, based on Bernoulli-Euler kinematics, incorporates surface effects such as surface elasticity, surface residual stresses, surface density, and rotary inertia. Hamilton's principle is applied to derive the governing equation with size-dependent considerations. The main outcomes of a parametric investigation, considering four different kinematic boundary conditions (Cantilever, Simply-Supported, Clamped-Pinned, and Doubly-Clamped) while varying the nonlocal parameter and material gradient index, are presented and discussed. Additionally, the normalized natural frequencies for the second, third, fourth and fifth modes of vibrations are provided and analyzed for each case under study. The results underscore the model's effectiveness in capturing surface energy effects on the overall dynamic behavior of functionally graded Bernoulli-Euler nanobeams, offering a cost-effective approach for designing and optimizing nano-scaled structures.
Measurements of the Effective-Stress Coefficient for Elastic Moduli of Sandstone in Quasi-static Regime Using Semiconductor Strain Gauges
Authors: Mikhaltsevitch Vassily , Lebedev Maxim
Published: January 2024

Numerous experimental and theoretical studies undertaken to determine the effective-stress coefficient for seismic velocities in rocks stem from the importance of this geomechanical parameter both for monitoring changes in rock saturation and pore pressure distribution in connection with reservoir production, and for overpressure prediction in reservoirs and formations from seismic data. The present work pursues a task to determine, in the framework of a low-frequency laboratory study, the dependence of the elastic moduli of n-decane saturated sandstone on the relationship between pore and confining pressures. The study was conducted on a sandstone sample with high quartz and notable clay content in the quasi-static regime, when the 100 ml tank filled with n-decane was directly connected to the pore space of the sample. The measurements were carried out at a seismic frequency of 2 Hz and strains, controlled by semiconductor strain gauges, not exceeding 10-6. The study was performed using a forced-oscillation laboratory apparatus utilizing stress-strain relationship. The dynamic elastic moduli have been measured in two sets of experiments: at constant pore pressures of 0, 1 and 5 MPa and differential pressure (defined as a difference between confining and pore pressures) varied from 3 to 19 MPa; and at а constant confining pressure of 20 MPa and pore pressure varied from 1 to 17 MP. It was shown that the elastic moduli obtained in the measurements are in good agreement with the Gassmann moduli calculated for the range of differential pressures used in our experiments, which corresponds to the effective-stress coefficient equal to unity.
Assessment of the Pollution Present in School Playgrounds in the City of Murcia (SE Spain)
Authors: Delgado Iniesta Maria José , Marín-Sanleandro Pura , Canca Pedraza Maria del Carmen , Diaz-Pereira Elvira , Sánchez-Navarro Antonio
Published: January 2024

Urban dust samples were taken from the playgrounds of 27 schools located in the urban area of the city of Murcia (S.E. Spain). Their color and degree of magnetism were determined, as well as their heavy metal content (Cd, Cu, Cr, Ni, Pb and Zn) to evaluate contamination by environmental and health indexes. The highest concentration of contaminants is found in dusts of dark color and medium and high magnetism. The concentrations of heavy metals in the dust were, in this order, Zn (453.74 mg kg-1)> Cu (77.44 mg kg-1)> Cr (67.93 mg kg-1)> Pb (55.72 mg kg-1)> Ni (18.56 mg kg-1)> Cd (0.42 mg kg-1). The analysis of the magnetic and non-magnetic fraction indicates that there is a concentration of all heavy metals in the magnetic fraction. According to the geoenvironmental indices used, the ecological risk presented by school playgrounds is moderate. As for the health indices, ingestion was the main route of exposure and entry of dust particles into the body, being the main health risk for adults and children for all metals. The Hazard Index (HI) values for all elements for both adults and children were less than 1, indicating that there is no risk of developing adverse health effects. As for the Cancer Risk (CR), the values of this index indicate that there is no risk. The objective of this study was to evaluate pollution in the playgrounds of schools in the city of Murcia.
Evolutionary Machine Learning for Intelligent Health Risk Prediction
Authors: Tarekegn Adane , Alemu Tamir
Published: January 2024

Evolutionary Machine Learning (EML) has demonstrated its effectiveness in modeling various real-world application domains, including the dynamics of diseases and the creation of predictive models across diverse fields. However, the challenge of data imbalance adversely impacts the performance of EML models. While strategies involving misclassification costs or cost-sensitive learning exist to address this issue, their integration into EML has yet to be thoroughly explored. This paper aims to fill this gap by investigating the application of cost-sensitive EML for intelligent health risk prediction. More specifically, this paper delves into the utilization of cost-sensitive genetic programming (CSGP) and cost-sensitive genetic algorithms (CSGA), which are among the most widely used algorithms in the EML category. The study entails training CSGP and CSGA to predict the early onset of three chronic conditions (hypertension, diabetes, and fatty acid-related disorders) through the development of an EML model. Subsequently, the model's performance is evaluated through standard fitness functions such as sensitivity, specificity, and F1-score. From the experimental results, EML models demonstrate promising results in identifying the occurrence of chronic diseases. Further optimization of the cost-sensitive EML model holds the potential for enhanced outcomes in modeling medical problems.
Association between Spirituality and Depression in Elderly People with Parkinson’s Disease in Brazil: Cross-Sectional Study
Authors: Zuge Samuel Spiegelberg , Grasel Julia , Watte Alessandra Paula , Gasparin Vanessa Aparecida , Corralo Vanessa da Silva
Published: January 2024

Parkinson’s disease affects a significant number of elderly people around the world, and it is characterized by a variety of motor and non-motor symptoms. Among non-motor symptoms, depression has shown a high prevalence. Nonetheless, complementary therapies have been sought with a view to improving the mental health and quality of life of this population, where spirituality has proven to be a method capable of contributing to the improvement of depression. Accordingly, the objective is to analyze the relationship between spirituality and depression in elderly people with Parkinson’s disease. This is a cross-sectional study, carried out with 35 elderly people living in a municipality in the state of Santa Catarina/Brazil, diagnosed with Parkinson’s disease. It was possible to measure that the higher the general, religious and existential domains of the Spiritual Well-Being Scale, which involve feelings of completeness and satisfaction with life, peace with oneself and the world, and the higher the organizational domain of the Duke University Religion Index, which mainly involves the social component (participation in religious meetings), the lower will be the depression levels in people with Parkinson’s disease. Accordingly, it is concluded that spirituality can, in some way, contribute to the reduction of depression levels in elderly people with Parkinson’s disease.
Effectiveness of Millet-Pulse-Groundnut Based Formulations in Improving the Growth of Pre-school Tribal Children in Telangana State, India
Authors: Datta Mazumdar Saikat , Afari-Sefa Victor , Selvaraj Aravazhi , Durgalla Priyanka , Seetha Anitha , Nedumaran Tamilselvi , Nancy Divya , Mane Harshvardhan , Bhattacharjee Suchiradipta , Swamikannu Nedumaran , Raman Anitha , Banerjee Roopa , Padmanabhan Jyosthnaa , Bose Disha
Published: January 2024

A community-level nutrition intervention was implemented among tribal children (3 to 6 years) in Telangana, India. The one-year intervention involved six nutrient-rich formulations of millet-pulse-groundnut based products, suited to local taste preferences. Anthropometric measurements of height, weight and Mid-Upper-Arm -Circumference (MUAC) along with haemoglobin (Hb) levels were monitored at baseline and endline. The treatment group showed considerable gain in height (3.2 cm), weight (1.68 kg) and MUAC (0.33 cm), over the control group. Paired t-test indicated significant differences (p<.01) between pre- and post-intervention anthropometric measurements. Positive shifts were observed in wasting (WHZ; -1.2 ±1.3 to -0.9± 1), stunting (HAZ; -1.8±1.6 to -0.3±1.3) and underweight (WAZ; -1.9±1.2 to -0.7±1) among treatment group. Hb levels in the treatment group also improved significantly from 9.70 ± 0.14 g/dl (moderately-anaemic) to 11.08 ± 0.13 g/dl (non-anaemic). Post-intervention Focus Group Discussions (FGDs) involving mothers and teachers confirmed the positive impact. Thus, nutritional intervention formulated using climate resilient millets, pulses and groundnut, promotes dietary diversity and improves the nutrition & health status of children.
Eating Behavior and Chronic Stress in a Post-pandemic Context Study with Portuguese Young People Aged 15–26 Years
Authors: Candeias Adelinda Araujo , Félix Adriana Simões
Published: January 2024

The eating behaviors of young people underwent substantial changes due to the COVID-9 19 pandemic. This study addresses the understanding of pandemic impacts on perceived psycho-10 logical and physical well-being exploring the connection between self-perceived eating behavior 11 quality and chronic stress. A sample of Portuguese young people aged 15-26 years (N=951), com-12 pleted a self-report questionnaire assessing socio-demographic data, perception of eating quality 13 behavior, appetite, stress, well-being and optimism. The results reveal gender differences, with 14 males scoring higher in well-being and optimism, while females exhibit elevated appetite and 15 chronic stress scores, and also reveals negative links between age group and eating quality and 16 chronic stress, and positive links between eating quality and well-being. Well-being emerges as a 17 significant predictor of stress in middle and oldest young adults that maintain or increase quality of 18 eating behaviors, while optimism plays a paradoxical role in predicting higher stress in younger 19 adults with reduced eating quality. These results emphasize the need to consider eating behaviors 20 and stress among young adults as an investment in global public health, given the significant rep-21 resentation of young adults in the population, to mitigate long-term health risks. Effectively reduc-22 ing detrimental eating behaviors and stress in these demographic groups can enhance overall well-23 being and longevity.
Using Basic Quantum Circuits to Simulate 1D Ising Model
Authors: Luo Jiaming
Published: January 2024

The Ising model, a cornerstone in the understanding of critical points, phase transitions, and magnetic systems, has been pivotal in advancing our knowledge of statistical physics. Although analytical solutions exist for the 1D and 2D Ising models, complexities rise significantly with the inclusion of external magnetic fields and in higher dimensions. Here, we demonstrate a novel quantum computational approach to simulate the 1D Ising model with basic quantum gates in the QISKIT(Python) that is both accessible to beginners and executable on personal computers, bypassing the need for advanced computational infrastructure. By initializing the system in a comprehensive superposition state, we effectively utilize quantum gates to replicate the intricate interactions between spins and external fields. This method offers a more intuitive and direct observational means of the system's evolution, distinguishing it from previous methodologies. Our results not only repeat all the physics behavior in the 1D Ising model but also showcase the expanding capabilities of quantum computing to tackle complex physical systems, promising advancements in both theoretical and applied physics.
Maturity Model for Sustainability Assessment of Chemical Analyses Laboratories in Public Higher Education Institutions
Authors: Souza Marco Antonio , Gonzalez Mario Orestes , Pinho Andre Luis
Published: January 2024

The increasing demand for sustainable products and services has become a constant requirement by the different stakeholders in an organization. Higher Education Institutions (HEI) have a crucial role in training conscious and competent professionals to lead these changes. Chemical analyses laboratories bring together the proper mix, where the adoption of mature and efficient management systems proves to be crucial not only to better train the institutions´ human resources but also to cooperate in recruiting research projects and other services to benefit society. Maturity models assist in the needed stages for sustainable growth to take place. This paper proposes a Maturity Model based on standardized norms to guide adjustments related to quality, risks, safety, and environment of chemical analyses laboratories in public higher education institutions. This research was done in four stages: theoretical research about Maturity Models, sustainability, and integrated management systems; survey with laboratories; case study at a chemical analyses laboratory of an HEI; and structuring and validating a maturity model. As a result of this, the model includes eight dimensions (Strategy, Leadership, Management, Operations, Continuous Improvement, Sustainability, Culture, and Integration), 31 subdimensions, and 204 management practices to assess and guide chemical analyses laboratories to sustainable maturity levels.
Analysis of the Efficacy of an Affective-Sexual Education Program and Health Perception in 14- to 15-Year-Olds
Authors: Zafra-Agea Jose Antonio , Sierra-Yagüe Alba , Leon-Rel Vanesa , Lima-Serrano Marta
Published: January 2024

Abstract: Objective: The aim of this study is to evaluate the effectiveness of an affective-sexual education programme among 14-15 year-old adolescents and its impact on their perception of their health. Design: This is a quantitative, descriptive and prospective quasi-experimental study, employing various cross-sections throughout the school year. It constitutes an educational promotion intervention where a health blog serves as a supplementary component to the "Health and School" programme. This phase is assessed using specific tools designed to evaluate scales. The study aims to assess the programme's effectiveness in the areas of knowledge and attitudes related to sexuality, sexually transmitted diseases, and affectivity. Additionally, it aims to evaluate the intervention's impact on 292 secondary school students, divided into a control group (N=144) and an intervention group (N=148). Both groups belong to the same population and have undergone affective-sexual education interventions focusing on gender and sexual diversity perspectives. The assessment considers perceptions and behaviours related to knowledge about HIV and other STDs/STIs, attitudes towards HIV, health anxiety, and AIDS phobia. Cross-sectional comparisons between the control and intervention groups are conducted at three points during the school year: longitudinal study, baseline, at month 4, and at month 9 post-intervention. Methods: Median and interquartile range, Wilcoxon test for numerical variables and Fisher's test for categorical variables were calculated according to intervention group. Results: 53% of the students reported a very good perception of health, compared to 45% with a good perception. Boys reported a good perception of health (85%) and had perceptions of their physical appearance and health (p=0.023) and (p<0.001) in the intervention group. Differences were found between perceptions of physical appearance in the control group, which was close to normal (p=0.429). In terms of level of knowledge about HIV and other STDs/STIs, the most significant difference was found in knowledge about HIV transmission, which varied between groups. Conclusions: Early affective-sex education sessions have an impact on health perception and behaviours related to knowledge about HIV and other STDs/STIs, leading to reduced anxiety in adolescents. School nurses should focus on health promotion, prevention of sex-related diseases, healthy attitudes from a gender perspective and integrated affective relationships in all their dimensions.
The Role of Multimodal Imaging in Congenital Optic Nerve Anomalies: From Bedside to Diagnosis
Authors: Cennamo Gilda , Rinaldi Michele , Concilio Marina , Costagliola Ciro
Published: January 2024

Abstract: In this comprehensive review, we delve into the significance of the mul-timodal imaging in diagnosing and managing of complications of congenital optic nerve anomalies.. While the Fundus examination is the gold standard tool in diagnosisc of these pathologies, SD OCT and OCTA could shed a light in the pathogenesis, and treatment. Moreover , this review seeks to offer a comprehensive insight into a multimodal approach of these rare congenital pathologies. In conclusion, congenital anomalies of the optic nerve represent a major challenge for ophthalmologists Further research could be clarify the pathophysiology of these diseases and define a correct and specific treatment approach.

Keywords: keyword 1; ODC, ODP, MGS, OCT; OCTA, Multimodal imaging.