bluuebunny/crossref_metadata_2025 huggingface dataset:
Enfermedad de Pompe y compromiso respiratorio
Authors: Varón Vega Fabio
Published: October 2023

Introducción: el compromiso respiratorio en la enfermedad de Pompe es una de sus manifestaciones más frecuentes, tiene un impacto negativo en la calidad de vida y facilita la aparición de múltiples complicaciones. Se puede presentar como parte evolutiva de la enfermedad o incluso ser el síntoma inicial de la patología.
Contenidos: la presentación clínica del compromiso respiratorio en la enfermedad de Pompe se caracteriza por disnea, ortopnea, cefalea y tos, y sus cambios paraclínicos incluyen hipercapnia, policitemia, elevación del índice de apnea/hipopnea, así como disminución de la capacidad vital y de las presiones inspiratoria y espiratorias máximas. El compromiso respiratorio es causado principalmente por disfunción muscular (especialmente el diafragma) y alteración de la regulación del sistema nervioso central.
Conclusiones: es fundamental la valoración acuciosa inicial de los patrones respiratorios y por supuesto su seguimiento, el cual dependerá del tipo de progresión de la disfunción respiratoria (rápida o lenta) o del requerimiento específico para cada paciente (ventilación no invasiva o invasiva).
Genetic diversity of Mycobacterium tuberculosis strains isolated from spiritual holy water site attendees in Ethiopia.
Authors: Reta Melese Abate , M Halima Said , Maningi Nontuthuko Excellent , Wubetu Gizachew Yismaw , Agonafir Mulualem , Fourie P. Bernard
Published: October 2023

The genetic diversity and drug susceptibility profiles of
Mycobacterium tuberculosis (M.tb) strains were characterized
among isolates from individuals with pulmonary tuberculosis (PTB)
symptoms attending spiritual holy water sites (HWSs) in the Amhara
region, Ethiopia. A cross-sectional study was done from June 2019 to
March 2020 to investigate mycobacterial diversity and drug-resistance
profiles of isolates. Of 560 PTB symptomatic participants, 122 (21.8%)
were culture-positive cases(Löwenstein-Jensen culture). Spoligotyping of
116 isolates revealed diverse M.tb genotypes, with CAS1-Delhi
(30.2%), T3-ETH (14.7%), T2 (10.3%), T1 (8.6%), and CAS1-Kili
(6.9%) predominating. SIT149/T3-ETH and SIT26/CAS1-Delhi (with 17 and
16 clustered isolates) were prevalent in Euro-American, and East-African
Indian lineages, respectively. Of the 122 culture-positive isolates
tested with GenoType®MTBDR plus v2 and GenoType®MTBDR sl
v2, 16.4% were resistant to rifampicin (RIF) and/or isoniazid (INH).
Multidrug-resistant TB (MDR-TB) was detected in 12.3% of isolates, five
of which were pre-extensively drug-resistant (pre-XDR). SIT149/T3-ETH
and SIT21/CAS1-Kili sublineages showed a higher proportion of drug
resistance. Diverse genotypes and a high prevalence of drug-resistant TB
were observed amongst the HWS attendee target group in the study, with
SIT149 and SIT21 sublineages accounting for a greater share of drug
resistance. This underlines the importance of strengthening TB control
programmes, and TB case detection in HWSs.
The effect of pairing assistance under medical alliance policy on healthcare utilization for patients with chronic diseases in rural China
Authors: Tang Haoqing , Li Mingyue , Zhu He , Cheng Xiaoran , Liu Xiaoyun
Published: October 2023

Pairing assistance (PA) of health professionals between county hospitals
and township health centers is one of the key components of the reform
of medical alliances in China to strengthen the development of health
workforce in primary health care (PHC). This study aims to examine the
effect of PA on healthcare utilization for patients with chronic
diseases in rural areas. Two waves of National Health Services Survey
(2013 and 2018) were used. A total of 13893 and 22725 rural residents
with chronic diseases were included in the 2013 and 2018 waves,
respectively. Multiple logistic regressions were used to examine the
associations between PA and outpatient and inpatient service utilization
in PHC. Chow test was used to examine the difference between PA in two
models. Among rural patients with chronic diseases, two-week outpatient
visits increased from 22.69% to 27.54%, and annual hospitalization
admission increased from 20.72% in 2013 to 25.44%. PA was associated
with a significant decrease in outpatient visits (p<0.001) in
2018 after controlling for individual and county characteristics.
Patients in PA counties were 1.45 times (95% CI 1.10-1.90) more likely
to use PHC outpatient care in 2013, but the difference disappeared in
2018 (OR=0.85, 95% CI 0.71-1.01). PA did not reverse the downward trend
in the share of PHC outpatient visits. PA under medical alliances in
China provides a potential model for building integrated people-centered
health systems for other low- and middle-income countries.
Into the Unknown: Maternal Responsiveness Influences Young Children’s Support-Giving Expectations of Fathers but Not Unfamiliar Others
Authors: Jia Chenglong , Shen Yuan , Zhu Ling , Sun Li , Du Kelin , Qin Jinliang
Published: October 2023

Interactions with primary caregivers shape children’s expectations of
interactions with others, but the mechanism is not clear yet. We
included Han Chinese children aged 5–6 (N = 121, 61 boys) from a city
in East China and tested their support-giving expectations of mothers,
fathers, and unfamiliar others after observing mother-child interactions
with different levels of maternal responsiveness. Across two studies, we
found that children’s support-giving behavior and willingness
expectations decreased significantly in the unresponsive condition for
mothers and fathers but not for unfamiliar others. The results suggest
that relationship type between children and interaction partners
moderates the effects of maternal responsiveness on children’s
expectations of partners’ support-giving. They shed light on how young
children understand and represent interpersonal interactions.
Evaluated the cross-protection by intranasal administration of Vero cell-derived attenuated influenza vaccines with compound adjuvant
Authors: Ze Liu
Published: October 2023

Objective: This study was to evaluate the sufficient safety and
effect of the novel influenza vaccine program, using Vero cell derived
live attenuated influenza vaccine (LAIV) with compound adjuvant, through
intranasal administration; Methods: It prepared new reassortant
Vero cell adaption virus, and taken high yield. According to the plaque
counting, one dose LAIV was composed with 10 PFU of
H1, H3, BY and BV, respectively, in 0.1 mL volume. Then mixed this LAIV
with compound adjuvant, containing 500 μg/mL of carbopol971P and 50
μg/mL of tetanus toxin. That vaccination was called catt-flu. And it
employed the GYZZ02 vaccine (commercialized freeze-dried LAIV, listed in
China) as cohort analysis control. The total of two immunizations, by
immunize once every two weeks, it used the neutralization test,
neuraminidase inhibition, hemagglutination inhibition and animal
challenge-testing to detect the cross-protection of catt-ful by
intranasal administration. Pathological observation and weight
monitoring methods were used to detect its safety; Results:
That catt-flu program could induce more cross-protection with
neutralizing antibody against heterogeneous types of influenza virus,
not only based on HA but also NA protective antigen, through convenient
nasal immunization, which had non-inferiority titter compared with the
chicken embryo-derived GYZZ02 vaccine on safe and effect;
Conclusion: The Vero cell-derived vaccine (LAIV) combined
compound catt adjuvant (contain carbopol971P and tetanus toxin), could
provide another safety and protective program of influenza vaccine by
intranasal administration, as catt-flu program.
HOW MATERNAL SYMPTOMS AND SENSITIVITY PREDICT PREDICTORS OF ATTACHMENT SECURITY IN LOW SES TURKISH MOTHER-TODDLER DYADS
Authors: Önder Feyza Elif , Karabulut Deniz Hazal , Arikan Gizem , Kumru Asiye
Published: October 2023

We examined the association between maternal mental health
symptomatology, sensitivity, and toddlers’ attachment security in a
low-SES Turkish sample. Mothers (N= 148) and their 12- to 38-month-old
toddlers (Mage = 23.18 months) from economically impoverished
backgrounds were recruited. Home visits involved naturalistic home
observations of mother–toddler interactions and filling out
questionnaires including Brief Symptom Inventory. Trained coders
independently assessed video-recorded mother-toddler interactions for
maternal sensitivity and toddlers’ attachment security using the
Maternal Behavior Q-Sort and with Attachment Q-Sort, respectively.
Maternal symptoms were negatively associated while maternal sensitivity
was positively associated with attachment security. In the final model,
after controlling for SES, maternal sensitivity was the only predictor
for toddlers’ attachment security. We showed that the importance SES and
maternal factors on attachment security in a disadvantaged group, which
would facilitate developing preventive interventions specifically
addressing maternal mental health and high-risk groups.
Low-Cost Photogrammetry Rig for 3D Crop Modelling and Plant Phenomics
Authors: Hrzich Joe , Bidinosti Christopher P. , Beck Michael A. , Henry Christopher J. , Manawasinghe Kalhari , Tanino Karen
Published: October 2023

Photogrammetry is the science of obtaining a 3D scan of an object.
Through this process, reliable information about the physical object’s
complex structure can be obtained, studied and analysed. A low-cost
Structure from Motion (SfM) technique can be used to create 3D models
using multiple 2D images from different viewpoints. A point cloud is a
widely used 3D data form, which can be produced by depth sensors, such
as LIDARs and RGB-D cameras. However, the cost of such scanners can be
prohibitive, putting photogrammetry out of reach for many researchers
and practitioners in the agriculture industry.

We are developing a low-cost close-range photogrammetry rig that could
be a beneficial tool for agronomists, plant scientists, and breeders.
Our imaging system utilizes the Raspberry Pi to capture images with
multiple cameras, and a commercial rotatory table to get images from
different viewpoints. We discuss the development of extracting
quantitative trait indices in wheat in order to automatically
characterize planophile versus erectophile canopy architectures. Moving
forward, we plan to use our photogrammetry rig for a variety of
applications such as growth monitoring and extracting plant traits such
as number of leaves, stem height, leaf length, leaf width, leaf area,
and canopy volume. We also plan on developing bespoke, plug-and-play
systems that are tailored to the specific needs of a researcher and can
be operated with minimal expertise.
Dasiglucagon Treatment of Postprandial Hypoglycemia After Gastric Bypass: a Randomized, Double-blind, Placebo-controlled Trial
Authors: Nielsen Casper K. , Øhrstrøm Caroline C. , J. K. Houji Inas , M. Helsted Mads , S. L. Krogh Liva , J. Johansen Nicklas , Hartmann Bolette , Holst Jens J , Vilsbøll Tina , Knop Filip K.
Published: October 2023

Objective: Post-bariatric hypoglycemia affects more than 50% of Roux-en-Y gastric bypass-operated individuals. Despite the often debilitating nature of this complication, existing treatment options are limited and often inefficient. Dasiglucagon is a stable glucagon analog available in a ready-to-use formulation and recently shown to mitigate post-bariatric hypoglycemia in experimental settings. Here we aimed to evaluate the hypoglycemic hindering potential of dasiglucagon in an outpatient trial.

Research Design and Methods: We conducted a randomized, double-blind, placebo-controlled, crossover, proof-of-concept study at the Center for Clinical Metabolic Research at Gentofte Hospital Denmark. The study included 24 Roux-en-Y gastric bypass-operated individuals (23 females) with continuous glucose monitor-verified post-bariatric hypoglycemia (≥15 minutes, <3.9 mmol/L, ≥3 times/week) randomly assigned to two four-week treatment periods of self-administered subcutaneously 120 µg dasiglucagon or placebo. The primary and key secondary outcome were continuous glucose monitor-captured percentage of time in level 1 & 2 hypoglycemia (<3.9 & <3.0 mmol/L, respectively).

Results: Compared with placebo, treatment with dasiglucagon significantly reduced time in level 1 hypoglycemia by 33% (−1.2%-points; 95% CI −2.0 to −0.5, P=0.002) and time in level 2 hypoglycemia by 54% (−0.4%-points; 95% CI −0.6 to −0.2, P<0.0001). Furthermore, dasiglucagon corrected hypoglycemia within 15 minutes in 401 of 412 self-administrations as compared with 104 of 357 placebo self-administrations (97.3% vs 29.1% correction of hypoglycemia rate, P<0.001). Dasiglucagon was generally well tolerated, with mostly mild to moderate adverse events of nausea.

Conclusions: Compared with placebo, four weeks of self-administered dasiglucagon effectively reduced clinically relevant hypoglycemia in Roux-en-Y gastric bypass-operated individuals. ClinicalTrials.gov: NCT04836273.
The Best Arm Position for Therapeutic Ultrasound Application in Lateral Elbow Tendinopathy Patients
Authors: Stasinopoulos Dimitrios
Published: October 2023

Objectives: To determine which is the best arm position for Therapeutic Ultrasound (TUS) application in Lateral Elbow Tendinopathy (LET) patients. Patients and Methods: A randomized clinical trial was carried out with 33 patients who had Let in a research center. They were randomly allocated to three groups. Group A (n=11) was treated with were treated with an exercise program and application of TUS with the wrist in full flexion. An exercise program and application of TUS with the wrist in mid position between flexion and extension was given to group B (n=11). Group C (n=11) received an exercise program and application of TUS with the wrist in full extension. All patients received three treatments per week for six weeks. The pain was evaluated using a visual analogue scale and function using a visual analogue scale and pain-free grip strength at the end of the four-week course of treatment (week 4) and one month (week 8) after the end of treatment. Results: The application of TUS with the wrist in full extension produced the largest effect in the reduction of pain and in the improvement of function at the end of the treatment (P<0.05) and at any of the follow-up time points (P<0.05). Conclusion: The application of TUS with the wrist in full extension was the most effective treatment. Future well-designed studies are needed to confirm the results of the present trial.
Histopathological Inspection of the Occurrence of Lung Adenocarcinoma in Sheep in Tehran Province
Authors: Shahi Saman
Published: October 2023

Sheep pulmonary adenomatosis is a chronic respiratory disease with a long incubation period that many countries have long recognized. This disease is specific to sheep and most prominent in sheep over three years old. The cause of this disease in sheep is Beta Retroviruses (JSRV) which are transmissible among sheep. Since 1342, there have been reports of clinical cases of the disease in different regions of Iran. So far, histopathology has been one of the best diagnostic methods for this disease. The conducted research inspects the occurrence rate and pathological lesions of this disease in a slaughterhouse located in Tehran. All the studied sheep in this research were bred in the livestock farms of Tehran province and referred to the slaughterhouse. During routine inspections, the lungs that showed different macroscopic signs of pneumonia had been primarily identified and recorded; later, more thorough evaluations of macroscopic and microscopic examinations were performed. One hundred sheep lungs, which showed visible lesions of interstitial pneumonia, were selected for histopathological research. These lungs were generally heavy, edematous, had no signs of collapse, showed rib marks on the lung parenchyma, and appeared waterlogged in some cases. The affected areas were firm and light grey in some lungs. OPA histopathological lesions were observed and documented in 25 out of 300 suspicious lung samples. All twenty-five of the damaged lungs were almost similar in histopathological appearance and showed papillary protrusions consisting of short cuboid to columnar cells inside the ducts of alveoli and bronchioles, respectively. In the atypical form of the disease, which included all cases observed in the present study, infiltration of mononuclear cells and connective tissue was more substantial; large and foamy macrophages were also observed in the alveoli and bronchioles that were present in the vicinity of neoplastic lesions. The classical form of OPA, characterized by the infiltration of macrophages and lymphocytes and the formation of neutrophilic and fibrin molds, was observed in any of the cases.
THE ROLE OF ANTICOAGULANT, THROMBOLYTIC, AND FIBRINOLYTIC ACTIVITIES IN THE PREVENTION OF PERITONEAL ADHESION
Authors: DEYNEZ Gizem , MİSER SALİHOĞLU Ece , SÜNTAR İpek
Published: October 2023

Peritoneal adhesion occurs as a result of surgery, peritoneal injury, peritonitis, hypoxia, and ischemia. Surgical trauma causes many pathophysiological processes which include inflammation, oxidation, coagulation, fibrinolysis, cell proliferation, and apoptosis. After intra-abdominal operations, the adhesion tissue may occur on the peritoneal surface due to low fibrinolytic activity. This may result in permanent excessive adhesion tissue bands instead of properly formed fibrin structures. Therefore, anticoagulant, thrombolytic, and fibrinolytic activities have a key role in preventing peritoneal adhesion. Indeed, several studies have been conducted to find out new and effective agents against intra-abdominal adhesion. Thus, revealing the causes, development processes, and investigation techniques are highly important for designing and conducting such scientific studies. In this context, this study aims to summarize the pathophysiological processes of above-mentioned activities and to emphasize their importance in the peritoneal adhesion model as well as to explain the evaluation methods, particularly in terms of the investigation of natural products.
Editorial
Authors: Tavares Luis Eduardo
Published: October 2023

O dossiê "Inteligência Artificial: questões éticas e estéticas", dividido entre as edições de número 47 e 48 da Aurora, revista de arte, mídia e política da PUC-SP, visa contribuir com esta fase de reflexões sobre a Inteligência Artificial, a identificação e o diagnóstico de seus problemas. Em todos os artigos, as questões éticas e estéticas estão presentes de forma intrincada.
canto da sereIA
Authors: Vianna Sobrinho Luiz
Published: October 2023

Neste ensaio pretendemos demonstrar a necessidade de reflexão sobre o domínio do conhecimento advindo das novas tecnologias de informação agrupadas sobre a sigla de Inteligência Artificial. Partindo de linhas gerais, direcionamos o olhar crítico para a questão da atenção à saúde, da prática médica e da virada epistemológica da medicina de dados. O ponto crucial para a abordagem ética é a possibilidade e necessidade de acesso ao conhecimento socialmente construído que se anuncia, mas chamando a atenção para as armadilhas da economia política, expressas nas relações sobre o imenso poder dessas tecnologias. O que pode estar em jogo, além de radicalização da relação exploratória entre trabalho e capital, é a própria descaracterização do ethos humano.
Contribuições da psicologia funcionalista de John Dewey à neurociência cognitiva
Authors: Soler Leonor Gularte , Afonso Oliveira Neiva
Published: October 2023

Este artigo propõe-se a refletir sobre a relação da epistemologia instrumentalista de John Dewey com a neurociência cognitiva, a partir de sua crítica à psicologia tradicional. Realiza-se uma análise da tentativa de John Dewey de relacionar a verdade com a cognição destacando seus argumentos fundamentados no progresso da fisiologia e da psicologia, no avanço da biologia e no desenvolvimento do método experimental. O texto discute a possibilidade de o pragmatismo de Dewey contribuir com a neurociência cognitiva, já que a atitude naturalista do autor em relação ao ser humano e todas as suas funções reforça que é a mente que toma as decisões e controla o comportamento.
The PENGARUH RELIGIUSITAS, HALAL KNOWLEDGE, HALAL AWARENESS, DAN SIKAP KONSUMEN TERHADAP NIAT BELI PRODUK SKINCARE HALAL BLP SKIN
Authors: Balqis Salsabilla Aura , Zulaikha Siti
Published: October 2023

Penelitian ini bertujuan untuk mengetahui pengaruh religiusitas, halal knowledge, halal awareness, dan sikap konsumen terhadap niat beli produk skincare BLP Skin di Kota Surabaya. Data diperoleh dari penyebaran kuesioner secara online. Penelitian ini menggunakan metode kuantitatif dan diolah menggunakan SEM-PLS. Hasil dalam penelitian ini menunjukkan bahwa religiusitas berpengaruh signifikan terhadap sikap dan niat beli konsumen, halal knowledge juga memiliki pengaruh signifikan pada sikap, serta halal awareness memang berpengaruh signifikan terhadap niat beli. Sementara hubungan antara halal knowledge dengan niat beli, halal awareness dengan sikap, dan sikap pada niat beli tidak signifikan. Untuk hasil hubungan mediasi melalui sikap, tidak ditemukan hubungan mediasi pada penelitian ini. Hasil ini memberikan implikasi untuk perusahaan yang bersaing dalam industri kosmetik. Halal awareness adalah salah satu faktor utama yang harus diperhitungkan dalam mempromosikan produk mereka.
Implementation of Project Based Learning for Cognitive and Psychomotor Students in the Basic of Workshop Technology Course Welding Sub-competency in the Automotive Engineering Study Program
Authors: Doni Rahma , Algifari Arif , Irvan Muhammad
Published: October 2023

The higher education curriculum adopts project-based learning (PjBL) method that emphasizes the provision of knowledge with the problem solving in an organized work project within study group. This is such a solution for the problems of current conventional learning method implementation that made low enthusiasm and slow understanding student especially for Automotive Engineering student in having welding practice in The Basic Workshop Technology Course. By using experimental method in this research to compare conventional learning and PjBL method toward twenty Automotive Engineering students to evaluate cognitive and psychomotor aspect. On the steps, the lecturer starts with provides theoretical enrichment and end with welding practice. To find out the effect of implementing this project-based learning, lecturer divides the class in two study groups by differentiating learning methods, namely the group with conventional learning and the group with PjBL learning. Comparison is made between conventional learning and PjBL learning with projects processed by statistical interpretation. The results of the study showed that there was a significant effect on the results of the psychomotor evaluation of students, but not too significant for the cognitive evaluation results. Based on this research, there is a prove that PjBL is good enough to increase student’s abilities in welding practice as psychomotor representation increment.
FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KEBERHASILAN KONTRAKTOR DALAM PENAWARAN KOMPETITIF UNTUK PEKERJAAN KONSTRUKSI DI GUNUNGSITOLI
Authors: Gea Detamisteryomen -
Published: October 2023

Berdasarkan observasi lapangan yang telah dilakukan, diketahui bahwa jumlah kontraktor pada sektor konstruksi jauh lebih tinggi daripada kebanyakan sektor ekonomi lainnya. Akibat persaingan yang ketat ini, banyak perusahaan konstruksi skala kecil dan menengah di negara berkembang gulung tikar dalam lima tahun pertama pendiriannya. Di Gunungsitoli, banyak kontraktor yang gagal dalam penawaran mereka untuk mendapatkan proyek konstruksi dan sebagian besar kontraktor yang berhasil dalam penawaran mereka mengalami pembengkakan biaya, penundaan dan pengabaian proyek. Terdapat 12 faktor yang paling sesuai dan telah didokumentasikan pada penelitian ini. Penelitian ini menggunakan kuesioner dan meminta responden menilai tingkat pentingnya faktor-faktor yang mempengaruhi harga tender kontraktor. Analisis dan hasil pengolaha data menggunakan Mean Item Score (MIS) untuk menilai perspektif para profesional. Ketersediaan bahan baku, produktivitas tenaga kerja dan tingkat keuntungan adalah tiga faktor pertama yang mempengaruhi harga tender dalam pekerjaan konstruksi dengan peringkat skor rata-rata 4,62, 4,54 dan 4,5. Pengujian Chi-Kuadrat dilakukan untuk mengetahui tingkat signifikansi faktor-faktor yang mempengaruhi harga tender terhadap tingkat keberhasilan kontraktor. Hasil yang diperoleh dari penelitian ini adalah ketersediaan bahan baku, produktivitas tenaga kerja dan tingkat keuntungan merupakan faktor penentu paling besar untuk mencapai tingkat keberhasilan proyek.
ANALISIS KELISTRIKAN SISTEM STARTER TIPE KONVENSIONAL UNTUK PENGGERAK MULA MOTOR BENSIN
Authors: Permana Tatang , Daryanto Eka , Hutajulu Olnes Yosefa
Published: October 2023

ABSTRAKTeknologi kelistrikan motor terdiri dari sistem starter, sistem pengapian dan sistem pengisian. Setiap sistem kelistrikan motor akan mengalami permasalahan sejala lamanya waktu dan cara pemakaian, tidak terkecuali pada sistem starter motor Bensin dan Diesel. Permasalahan yang lazim terjadi adalah motor starter performennya menjadi kurang, sehingga tidak dapat memutarkan flywheel motor tersebut kembali. Permasalahan tersebut terjadi pada sistem starter tipe konvensional. Tujuan penelitian ini adalah untuk mengetahui hubungan antara kuat arus listrik terhadap momen puntir pada motor starter tipe konvensional, dan mengetahui daya yang dihasilkan oleh motor starter tipe konvensional. Hasil analisis dan perhitungan pada sistem starter tipe konvensional adalah semakin besar kuat arus listrik yang dialirkan maka momen puntir yang dihasilkan semakin besar, hasil perhitungan daya input ke motor starter adalah 1,2 Kw yang akan menghasilkan daya output sebesar 0,9 Kw dengan nilai effesisensi daya sebesar 75 %, dan kuat arus yang digunakan untuk dapat menghidupkan motor, adalah arus listrik mengalir 100 A dengan tegangan 12 V dan torsi 3,28 Nm.Kata kunci: Motor starter Konvensional, Kuat arus, momen puntir, Effisiensi Daya Output dan Input
Analisa Pengaruh Kendaraan Muatan Berlebih/Overloading (OL) terhadap Umur Rencana Perkerasan Jalan Tol (Studi Kasus Ruas Jalan Tol Semarang ABC)
Authors: Batubara M Iqbal Zaihan , Simanjuntak Janter P. , Siregar Syafiatun
Published: October 2023

Setiap perkerasan jalan didesain dengan kapasitas beban maksimum tertentu, namun dalam praktiknya terdapat banyak kendaraan yang melebihi batas dimensi dan beban yang telah ditetapkan, yang disebut sebagai kendaraan Beban Muatan Berlebih atau Overloading (OL). Fenomena ini diduga memiliki dampak yang signifikan pada umur rencana perkerasan jalan, terutama pada rute logistik utama jalan tol. Oleh karena itu, diperlukan sebuah studi untuk melihat dampak populasi kendaraan OL pada umur rencana perkerasan jalan tol.Metode yang digunakan dalam studi ini didasarkan pada Manual Desain Perkerasan 2017, dan tujuannya adalah untuk mengevaluasi dampak beban kendaraan OL terhadap umur rencana perkerasan lentur, adapun data yang digunakan seperti Data Lalu Lintas Harian Rata-Rata Tahunan (LHRT), data geometrik jalan, didasarkan pada data lapangan aktual yang dikumpulkan pada rute logistik Jalan Tol Semarang ABC pada periode 2023 serta Data populasi muatan berlebih berdasarkan pembacaan alat Weight in Motion Bridge (WIM).Hasil analisis menunjukkan bahwa pengaruh populasi beban kendaraan OL sebanyak 5,76% dari total populasi lalin harian tahunan (LHRT) memiliki dampak penurunan umur rencana perkerasan lentur, dari awal umur rencana 20 tahun menjadi 17 tahun, dan pengaruh populasi beban kendaraan OL sebanyak 19% dari LHRT akan memiliki dampak penurunan umur rencana perkerasan lentur dari awal 20 tahun menjadi 13 Tahun serta peningkatan Faktor Ekivalen Beban rata-rata atau Average Vehicle Damage Factor (VDF) dari kondisi muatan normal sebesar 5,9245 menjadi 20,2062 pada kondisi OL sehingga diperoleh kesimpulan bahwa dengan adanya kendaraan OL memberikan dampak signifikan terhadap penurunan umur rencana sebesar -16% (OL 5,76%) dan -25% (OL 19%) serta rata rata peningkatan faktor Ekivalen Beban sebesar 241%.
The Oncolytic Effect of an Iraqi Newcastle Disease Virus Attenuated Strain (AMHA1) Against Colorectal Cancer Cells.
Authors: Essa Farah , Al-Shammari Ahmed , Al-Saffar Ali , Salman Marwa
Published: October 2023

Objective: The most recent World Health Organization statistics show that colorectal cancer is the third foremost cause of death by cancer among Iraqis. It has become necessary to search and develop novel and unconventional treatment methods. Oncolytic virotherapy is one of the innovative cancer therapeutics that showed to be safe and selective and there is increased efforts in the recent years to move them to clinic. For the reason we were developing our Iraqi strain of oncolytic NDV to fight colorectal cancer. Materials and Methods: This study tested the killing rate of Iraqi strain of Newcastle disease virus (AMHA1) on colorectal cancer cells and testing the safety on normal cells. The virus tittered using vero cells, and then the cytotoxic effect of the virus on both types of cells was determined using the crystal violet assay. Finally, we performed a morphological analysis using hematoxylin and eosin staining. Results: Newcastle disease virus 0.3 MOI causes significant cytotoxicity with prominent cytopathic effect in the colorectal cancer cell line HRT-18G with 50% percentage of growth inhibition, but not in the normal human fibroblast (NHF) percentage of growth inhibition where it was less than 20%.    Conclusion oncolytic NDV AMHA1 strain effective against colorectal cancer cells because it has selectivity in replication and safety profile.
Métodos e Técnicas de Pesquisas Científicas
Authors: Silva Luan Carlos Santos
Published: October 2023

Objetivo: O objetivo deste trabalho, consistiu em elaborar uma resenha crítica do livro métodos e técnicas de pesquisas científicas. O livro "Métodos e técnicas de pesquisas científicas" oferece um guia abrangente para estudantes e pesquisadores, auxiliando-os na compreensão e aplicação de abordagens científicas.
 
Método: O método consistiu na leitura e posterior resenha do texto que explora as diversas fases da pesquisa, da formulação das perguntas à análise dos resultados. Organizado por Lúcia Vaz de Campos Moreira e Jardelino Menegat, a coletânea de vinte capítulos aborda métodos como experimental, observacional e bibliográfico.
 
Resultados e Conclusão: O livro inicia com uma introdução à pesquisa científica, passando por métodos quantitativos e qualitativos, estudos de caso e técnicas de análise. Cada capítulo segue uma estrutura lógica, tornando o conteúdo acessível. Embora o equilíbrio entre métodos qualitativos e quantitativos seja destacado, a resenha ressalta a necessidade de explorar contextos específicos e aprofundar a análise estatística.
Implicações da Pesquisa: Em geral, a obra é elogiada por oferecer uma abordagem didática e orientadora aos leitores, contribuindo para uma formação consciente em práticas científicas.
Vegetable Seedlings Production Under Seed Magnetization and Use of Magnetized Water
Authors: Vieira Gustavo Haddad Souza , Grazzioti Rafaela Melim , Monaco Paola Alfonsa Vieira Lo , Meireles Robson Celestino , Garcia André Dalla Bernardina , Pereira Débora Cristina Silva , Chambela Neto Alberto , Hadadde Ismail Ramalho
Published: October 2023

Objective: This study aimed to evaluate the effects of seed magnetization (SM) and irrigation water (WI), using commercial (CO) and Neodymium (NEO) magnetizers, on the development of seedlings of lettuce, eggplant, cucumber, sweet pepper and okra.
 
Method: The experiment was conducted in a randomized block design, with 5 treatments for each species, with 4 replications, being T1: irrigation with non-magnetized water; T2: SM-NEO + non-magnetized water; T3: SM-CO + non-magnetized water; T4: non-magnetized seeds + WI-NEO; and T5: non-magnetized seeds + WI-CO. The following were evaluated: emergence speed, emergence time, percentage of emergence, dry matter, root length, stem diameter, number of leaves and plant height.
 
Result and conclusion: For lettuce, WI-NEO showed the best results and, for sweet pepper, SM-CO, irrigating with non-magnetized water. For cucumber, SM or WI provided a reduction in seedling formation time. For eggplant and okra, we recommended SM-NEO and irrigated with non-magnetized water. In general, seed magnetization caused better results than irrigation water magnetization.
 
Implications of research: Quality seedlings produced in short time and at low cost are of great importance for the formation of vegetable crops.
 
Originality/value: Seed magnetization and the use of magnetized water are innovative, low-cost technologies for producing seedlings of high vigor and quality.
Languagequests en la enseñanza de lenguas
Authors: Corrêa Helena Laura Trojahn , Beviláqua André Firpo , Fialho Vanessa Ribas
Published: October 2023

Este trabajo trata de la producción y de la implementación de una LanguageQuest sobre la discriminación en el contexto de la Pasantía Supervisada en Lengua Española. La investigación tiene como objetivo general investigar desafíos y posibilidades en cuanto al uso de LanguageQuests en clases de lengua española impartidas durante la experiencia de Pasantía Supervisada en Lengua Española en la Educación de Jóvenes y Adultos (EJA) – Enseñanza Secundaria. Para ello, fueron delimitados tres objetivos específicos: a) Producir una LanguageQuest para la enseñanza de lengua española en la EJA; b) Implementar la LanguageQuest producida con los estudiantes; y c) Identificar desafíos y posibilidades en cuanto al uso de LanguageQuest en el referido contexto. En lo tocante a la revisión de literatura, utilizamos autores que discuten el uso de WebQuests y de LanguageQuests, tales como Dodge (1995), Koenraad (2003) y Canto (2016). Hemos incluido, también, algunos aportes de Autor et. al. (2017), acerca de los Sistemas de Autoría Abiertos (SAA). En lo que se refiere a los aspectos metodológicos, consideramos, en el presente trabajo, la investigación-acción, con énfasis en las propuestas de Tripp (2005) y de Leffa (2021). Con relación a los resultados, entendemos que los objetivos del estudio fueron alcanzados, teniendo en cuenta que una LanguageQuest fue producida e implementada durante la pasantía supervisada, siendo posible registrar tanto contribuciones como dificultades a lo largo de ese proceso, no solo en lo que dice respecto a la dimensión docente, sino también en lo que se refiere a los estudiantes.
RDA:ssa edistetään aineistonhallintaa
Authors: Hepolehto Iina , Kuusniemi Mari-Elisa , Manninen Soile , Nykyri Susanna
Published: October 2023

Datamaailman sillanrakentajana toimiva Research Data Alliance (RDA) juhlisti kymmenettä toimintavuottaan maaliskuussa 2023 Göteborgissa; samassa kaupungissa järjestettiin ensimmäinen RDA-kokoontuminen vuonna 2013. Mitä kymmenessä vuodessa on tapahtunut ja mitä on tulossa seuraavien vuosien aikana?
Tekoälyretki tekoälyn silmin
Authors: STKS:n Uuden teknologian työryhmä ja Chat GPT 3.5
Published: October 2023

STKS:n Uuden teknologian työryhmä järjesti webinaarin tekoälystä kirjastossa 23.5.2023. Keväinen löytöretki tekoälyyn -webinaari keräsi runsaasti kiinnostusta, ja sen myötä työryhmä sai kerättyä runsaasti näkemyksiä tekoälyn mahdollisuuksista ja haasteista.
Urban Form and Real Estate Value in Msheireb Downtown Doha, Qatar
Authors: Aliyar Adheena Kottappurath , Major Mark David , Tannous Heba O , Al-Esmail Fatima R A
Published: October 2023

In the late 20th century, Doha’s rapid urbanization and globalization led to the loss of housing and the compact, traditional urban fabric in the old city center. The Qatari government and Msheireb Properties developed Msheireb Downtown Doha to bring urban living back with a contemporary re-interpretation of the traditional urban fabric and modern life conveniences. Our study's primary objective is to investigate the relationship between urban form and the rental value of residential units, identifying factors that might influence rental asking prices. The paper examines morphological characteristics through field surveys and the real-estate variables such as location, floor area, number of bedrooms/bathrooms, and asking price collected from publicly available real estate websites. The findings indicate that the residential units' layout and adjacent streets' morphological characteristics clearly define specific targeted user groups. Larger residential units target Qatari families via more bedrooms/bathrooms and quieter urban settings, emphasizing Islamic cultural values. Smaller units target ex-pat workers (especially Westerners) using open-plan layouts in more lively urban environments of the development. The price per square meter also increases for residential units closer to the Doha Metro station. The study reiterates the success of compact living for improving urban living in other neighborhoods of old Doha.
Pengaruh Pupuk Kandang dan Giberelin (GA3) Terhadap Produksi Benih Bayam Hijau (Amaranthus hybridus L.)
Authors: Mufidatin Ilfa Nur Laili , Azizah Maria
Published: October 2023

The high demand for spinach and the increasing number of people in the community are not supported by existing production. Efforts are needed to increase the production of spinach seeds to meet the needs. The purpose of this study was to determine the effect of manure doses and gibberellin concentrations on seed production and quality, of Amaranthus hybridus. This research was conducted from August to November 2022 in Munder Village, Yosowilangun District, Lumajang Regency. This study was designed with a factorial randomized complete block design (RCBD) with 2 factors and 3 replications. The first factor was the treatment of the dose of manure with 3 level of goat manure, (10 tons/ha, 20 tons/ha and 30 tons/ha). The second factor was the treatment of gibberellin concentrations with 3 gibberellin concentrations, (100 ml/l, 150 ml/l and 200 ml/l). Then the data obtained is tested using ANOVA, then followed with DMRT at error level 5%. The results showed that the dose of 30 tons/ha of manure had a very significant effect on the number of panicles 14.00 strands, biomass 77.66 gram. The treatment of gibberellin concentrations had a very significant effect on number of panicles (13.87 strands), stem diameter (0.8967 cm). The combination of the two treatments had a very significant effect on the weight of 1000 seeds (0.8929 gram).
Pengaruh Jarak Tanam dan Sistem Olah Tanah Terhadap Produksi Benih Jagung Komposit Varietas Lamuru (Zea mays L.)
Authors: Maulidani Rahmat , Sjamsijah Nurul
Published: October 2023

Corn production every year is getting higher which results in higher demand for corn seeds. So efforts are needed to optimize the rate of corn seed production. One of the efforts to increase corn seed production is to improve the cultivation technique of the lamuru variety by choosing the right spacing and tillage system. This study aims to determine the effect of spacing and soil tillage systems on the production of lamuru varieties of maize seeds. This research was conducted in the Jember State Polytechnic research field from August to November 2022. The research used factorial Randomized Complete Block Design (RCBD) method with 3 replications. The data will be analyzed using ANOVA and followed by the DMRT test at the 5% level. The first factor is the spacing (80×20 cm), (80×25 cm), and (80×30 cm). The second factor is the tillage system, with intervals without tillage, minimum tillage and maximum tillage. The results showed that the treatment spacing (80 × 30cm) had a highly significant effect on the parameters of the weight of the cobs planted 308.73 gr, the weight of seeds per ear 178.07 gr, and production per hectare 6.64 ton/ha. The perfect tillage system had a highly significant effect on the parameters production per hectare 7,08 ton/ha.
Aplikasi Asam Giberelin dan Peletakan Akar Terhadap Produksi Benih Padi (Oryza sativa L.) Varietas Situ Bagendit
Authors: Yudha Yanuar Satya , Rahmawati Dwi
Published: October 2023

Rice is one of the main food sources for the people of Indonesia, therefore it is necessary to increase rice production to meet these needs. The purpose of this study was to determine the interaction of Gibberellin application and horizontal root placement on rice seed production. This research was conducted in Triwungan Village, Kota Anyar Subdistrict, Probolinggo Regency from August to November 2022. The implementation of the research used a Randomized Group Design (RGD) which was repeated 4 times. The first factor is GA3 concentration which consists of 4 levels, namely G0 (0 ppm), G1 (200 ppm), G2 (250 ppm), G3 (300 ppm). The second factor is the placement of root position consisting of A1 (vertical placement), A2 (horizontal placement). Observational data were analyzed using ANOVA, if there was a significant difference between treatments, it was continued with LSD further test at 1% level. The results showed that horizontal root laying showed a result of 2.35 in the number of tillers 4 weeks after planting. Gibberellin concentration of 250 ppm with the results of 20.625 cm on the parameters of panicle length, 70.04 grains on the number of grains per panicle, 57.21 grains on the number of grains per panicle, 25.99 grams on the weight of 1000
Identifikasi Karakteristik Agens Hayati Aspergillus niger dan Uji Daya Hambat terhadap Perkembangan Penyakit Bercak Daun pada Kacang Tanah
Authors: Erdiansyah Iqbal , Zaini Qurroyah
Published: October 2023

Aspergillus niger is a species of nematophagi whose existence is very widely available in nature which is commonly found in various habitats and soil types, both tropical and subtropical. Aspergillus niger can be an environmentally friendly alternative control, because it acts as an antagonistic fungus, one of which is in inhibiting the development of Cercospora arachidicola fungus that causes leaf spot disease. This study aims to determine the effect of biological agents Aspergillus niger in inhibiting the growth of leaf spot disease Cercospora arachidicola in vitro. This research was carried out from September 2022 to December 2022 at the Plant Protection Laboratory of Jember State Polytechnic using a non-factorial Complete Randomized Design (RAL). Treatments include: A0: 0% (aquades), A1: 10% (10 g/100 ml), A2: 15% (15 g/100 ml), A3: 20% (20 g/100 ml), A4: 25% (25 g/100 ml), A5: 30% (30 g/100 ml). Each treatment was repeated 3 times. The data was analyzed using Analysis of Variance (ANOVA), if the data differed markedly, then continued with the 5% BNT Test. The results of the study for the percentage of inhibition of each treatment were, A0 (0%) = 0%, A1 (10%) = 41,11%, A2 (15%) = 44,44%, A3 (20%) = 60,47%, A4 (25%) = 61,27%, A5 (30%) = 65,07%
Pengaruh Harga Terhadap Kepuasan Pelanggan Nasi Jamblang di Kota Cirebon Provinsi Jawa Barat
Authors: Ramadhani Tantya Shifa , Sabila Difa Madani , Wachdijono Wachdijono
Published: October 2023

Customer satisfaction is the attitude of the customer after buying/consuming a product. Therefore every entrepreneur strives to be able to build, achieve and maintain customer satisfaction, so that his business is sustainable. This study aims to examine the effect of cost on customer satisfaction of jamblang rice in Cirebon City, West Java Province with dominant indicators reflecting these two variables. This research was conducted from April to May 2023 using a descriptive quantitative research design and survey method. The research population is an infinite number of jamblang rice customers in Cirebon City, therefore the technique for determining the number of samples is based on a predetermined loading factor which is equal to 0.6 so that the total sample is 100 respondents. Data analysis uses the Structural Equation Model instrument. The results of the study concluded that price has a real and positive influence on customer satisfaction (0.77) and the indicator that is most involved in price is "recommending prices to others" while for customer satisfaction is "fulfilled expectations". The results of this study are useful for the development of knowledge on customer behavior and can be a recommendation for jamblang rice business people in Cirebon City in order to achieve and or maintain customer satisfaction.
Analisis Viabilitas Isolat Bakteri Penambat Nitrogen Azotobacter 33 pada Bahan Pembawa dan Suhu Penyimpanan yang Berbeda
Authors: Ismiani Sri , Wilujeng Elly Daru Ika
Published: October 2023

Azotobacter is a microorganism that enhances nitrogen availability for plants and has the potential to be used as a biofertilizer. Assessing the viability of microorganisms within a biofertilizer is crucial in determining its quality. The carrier medium and storage temperature influence the viability of Azotobacter bacteria. Therefore, this research aims to identify the most suitable carrier medium and storage temperature to promote the growth of Azotobacter as a biofertilizer before its field application. The study was conducted at the Soil and Environmental Biotechnology Laboratory, Faculty of Agriculture, Bogor Agricultural University. The viability of Azotobacter was tested using Zeolite and Molasses as carrier media, and stored at temperatures of 4°C and 27°C. The parameters observed were the bacterial population count on the 14th day and the 28th day after inoculation. The results showed that the Azotobacter viability analysis using Zeolite as the carrier medium, storage at 4°C resulted in a population count of 3.7 × 106 CFU/ml, in comparison stored at 27°C resulted in an increased population count of 5.3 × 107 CFU/ml on the 28th day after inoculation. On the other hand, the Azotobacter viability analysis using Molasses as the carrier medium, storage at 4°C the bacterial population count reached 8.5 × 108, and storage at 27°C resulted in a bacterial population count of 7.9 × 106 on the 28th day after inoculation. It can be concluded that both of carriers have a good ability. The viability of Azotobacter is better in Molasses as the carrier medium, with storage at 4°C and the viability of Azotobacter is optimal in Zeolite as the carrier medium, with storage at 27°C, maintaining a stable population density without a decrease in the population count.
Intensifikasi Produksi dan Kualitas Benih Kacang Hijau (Vigna radiata L.) Melalui Aplikasi Pupuk Organik Cair dan Pengaturan Jarak Tanam
Authors: Mumtazi Ragil , Syaban Rahmat Ali
Published: October 2023

This research was conducted to determine the intensification of production and quality of green bean seeds (Vigna radiata L.) through the treatment of plant spacing and POMI liquid organic fertilizer. The mung bean seed variety used in this study was the Vima 1 variety. The research was carried out from August to November 2022 at the research area of ​​the Jember State Polytechnic. This study used a factorial randomized block design. The first factor was the spacing treatment consisting of three levels, namely J1 = 30 cm x 20 cm, J2 = 30 cm x 30 cm, and J3 = 30 cm x 40 cm. The second factor was the POMI liquid organic fertilizer treatment consisting of three levels, namely P1= 4 ml/l, P2= 8 ml/l, and P3= 12 ml/l. Data were analyzed using ANOVA and further tested using DMRT with an error level of 5%. The results showed that the J1 treatment (30 cm x 20 cm) had a highly significant different effect on the parameters of the number of pods per plant, namely 15.42, the production per hectare, which was 1.54 tons, and the weight of 100 seeds of 6.02 g. Treatment P2 (8 ml/l) had a highly significant different effect on the parameter number of pods per plant, namely 13.64. The P2 treatment (8 ml/l) had a significantly different effect on the production parameters per hectare, namely 1.02 tons. The P3 treatment (12 ml/l) had a significantly different effect on the parameter weight of 100 seeds, namely 6 g. The treatment of spacing and liquid organic fertilizer had no significant effect on germination parameters.