bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Transformation and Integration: Leveraging Talend for Enterprise Solutions
Authors:   Cyber Security Senior Data Analyst, Department of Cyber Security, Truist Financial, CA, USA, Kodi Divya
Published: February 2025

The increasing volume, variety, and velocity of data necessitate robust data integration and
transformation solutions. As enterprises shift towards data-driven decision-making, efficient data processing has
become a cornerstone of business success. Talend, a widely adopted open-source and commercial data integration tool,
offers comprehensive features for Extract, Transform, Load (ETL) processes, enabling organizations to manage their
data efficiently.
This paper explores the role of Talend in modern enterprise solutions, emphasizing its functionalities, advantages,
challenges, and case studies of successful implementations. The study examines the architecture of Talend, its ability to
integrate with cloud-based and on-premises environments, and its impact on data governance and security.
Furthermore, it evaluates Talend’s efficiency in handling big data and real-time processing compared to traditional ETL
tools. The findings indicate that Talend provides enterprises with a scalable, cost-effective, and flexible solution for
data transformation and integration. By leveraging Talend, organizations can ensure high data quality, streamline
business operations, and enhance analytics capabilities, thereby gaining a competitive edge in the evolving digital
landscape.
Characteristics of behavioral and socioeconomic risk factors for noncommunicable diseases in young people with comorbidities
Authors: Afanaseva A. D. , Shcherbakova L. V. , Gafarov V. V. , Shramko V. S. , Denisova D. V. , Ragino Yu. I.
Published: February 2025

Aim. To analyze behavioral and socioeconomic risk factors for noncommunicable diseases in young people with comorbidities.

Material and methods. The population sample included 1415 people. Comorbid pathology was considered a combination of ≥3 diseases. Comorbid pathology was detected in 105 examined people.

For comparison with comorbid patients, a group of healthy individuals without any of the studied diseases was formed (n=162).

Results. When assessing the main socioeconomic and behavioral characteristics, healthy individuals more often report a good self-perceived health compared to individuals with comorbid pathology, while no differences were found for poor self-perceived health between the groups. Individuals with a combination of ≥3 pathological conditions were more likely to smoke, and also more often had manifestations characteristic of eating disorders, namely abdominal obesity (AO), overweight, class I and II obesity. Morbid obesity was recorded only in individuals with comorbid pathology. According to univariate regression analysis with standardization by sex and age, comorbid pathology was associated with smoking, AO and a good self-perceived health. When including socioeconomic and behavioral characteristics in the regression model, the probability of comorbid pathology increased by >3 times in smokers, slightly <3 times in men, 2,5 times in AO and with a worse self-perceived health, and was also associated with an increase in age by 1 year.

Conclusion. Among young people, comorbid pathology is associated with male sex, smoking, AO and a worse health self-perception compared to healthy individuals.
Barriers to effective communication on adult vaccination: results of in-depth interviews with the population and healthcare professionals of the Arkhangelsk Oblast
Authors: Lopatina M. V. , Kriger E. A. , Nizovtseva N. R. , Kudryavtsev A. V. , Yakovleva V. A. , Zinovieva V. А. , Usova E. V. , Kontsevaya A. V. , Drapkina O. M.
Published: February 2025

The effectiveness of communication with a doctor on vaccination often determines a patient's decision to vaccinate. However, the related difficulties and barriers remain insufficiently studied.

Aim. To study the factors influencing communication between doctors and adult patients on vaccination issues.

Material and methods. Based on the World Health Organization approach to adapting immunization programs, a qualitative study was conducted in May-June 2024 in the Arkhangelsk region, including 18 semi-structured personal in-depth interviews on adult vaccination with two following target groups: adult population (n=12) and health workers (n=6). The interviews were transcribed and analyzed by two independent experts using narrative content analysis.

Results. According to population representatives, there were following factors hindering communication and consent to vaccination: lack of information about vaccines and possible reactions; no discussion of vaccination with a healthcare professional or a formal approach to it. According to health workers, the barriers were prejudices and myths about vaccines among the population. Among the management problems, the population noted the lack of time for doctors to discuss vaccination at the appointment; healthcare workers noted the lack of a unified information on vaccination issues, lack of visual information for patients, and logistical problems (impaired continuity in transferring information on vaccination of the population between health institutions and healthcare workers).

Conclusion. The identified barriers to effective communication on vaccination can form the basis for developing measures to eliminate them and increase adult vaccination coverage. The developed and presented tool for conducting personal in-depth interviews can be used by researchers and specialists in the field of public health promotion to study the problems of communication on adult vaccination.
AUDIENCIAS VIRTUALES, EQUIDAD E INMEDIACIÓN EN EL SISTEMA JUDICIAL PERUANO
Authors: Paye Apaza David Alberto , Roman Gil Carlos Adalberto , Rucoba del Castillo Luis Ronald
Published: February 2025

En el contexto global, donde la virtualidad transversaliza las áreas del conocimiento, resulta fundamental el abordaje y trazabilidad de los procesos de adecuación, donde el estudio sobre las implicancias dentro del sistema jurídico se concibe como crítico. El objetivo del estudio fue analizar la incidencia de las audiencias virtuales sobre los principios de equidad e inmediación en tribunales civiles y penales en Perú, 2024. El enfoque se inscribió en el paradigma socio jurídico. La investigación asumió un diseño no experimental, analítico y mixto, conformada por una muestra de 147 operadores jurídicos de tribunales civiles y penales; se aplicó la técnica de la encuesta. Los resultados evidenciaron que las audiencias virtuales presentaron limitaciones que comprometen los principios de equidad e inmediación, sobre todo en restricciones vinculadas con la interpretación de la comunicación no verbal y con dificultades técnicas emergentes que afectan tanto la interacción entre las partes como la capacidad de los jueces para realizar evaluaciones precisas de la credibilidad de los testigos. Se concluye que la transición a audiencias virtuales en Perú demanda una reforma integral del sistema judicial para preservar la equidad, inmediación y el acceso a la justicia en el entorno digital.
The energy cost of dribbling in field hockey
Authors: Chantler I
Published: February 2025

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Guía gráfica de porciones de alimentos
Authors:   Universidad de Antioquia, Zuluaga Rendón Natalia
Published: February 2025

Guía gráfica de porciones de alimentos es una obra derivada de la lista de intercambios elaborada por el Grupo de Investigación Alimentación y Nutrición Humana (GIANH), en su línea de Evaluación de Ingesta Dietética, grupo de Consumo de Alimentos Medellín y Seccional Oriente, en su quinta edición (2023).
Este material contiene ilustraciones que muestran los tamaños de las porciones de los diferentes grupos de alimentos, enfatizando en la lista de adultos y niños mayores de dos años, con lo cual sirve como instrumento educativo tanto a los profesionales de la salud como a los pacientes que busquen comprender mejor sus planes de alimentación.
Old and New Controversies around Institutional Architecture of the Bank of the Republic of Colombia in Its First 100 Years
Authors:   Universidad Externado de Colombia, Sastoque Ramirez Edna Carolina , Sandoval Luis Eduardo ,   Universidad Militar Nueva Granada
Published: February 2025

The presence of a central bank is fundamental in the financial system. Despite the technical consensus on its importance, political reality reveals the complexity of monetary systems, where actors with varying interests negotiate rules and establish governance processes. These systems evolve in response to the adjustment of political and social forces, adapting to the socioeconomic changes of each era. Therefore, this article explores the dynamism of the institutional design of the central bank, highlighting tensions and controversies regarding its objectives, organization, and management. Two periods are compared: the first, from 1923 to 1933, and the second, from 2020 to 2023, in the context of its centennial. Reports from the Board of Directors of the Bank of the Republic (Banco de la República, 2020a, 2020b, 2021a, 2021b, 2022a, 2022b, 2023a, 2023b) and Congress (2020-2023), as well as information from the Banking Superintendency and press reviews, are utilized. It concludes that the Bank of the Republic has evolved from a central bank with a Single Objective to a Mobile Objective, integrating inflation, growth, and employment, which implies greater alignment with political forces while maintaining its administrative and technical independence.
Calidad del empleo: una medición desde las preferencias de los trabajadores
Authors:   Seguros SURA, Cortés Yennifer , Cortés María Daniela ,   ICETEX, Rodríguez David ,   Universidad Externado de Colombia, Rozo Cindy ,   Aerocivil
Published: February 2025

La literatura en economía laboral para países en desarrollo emplea frecuentemente índices sintéticos para estudiar los empleos de calidad, esto en especial debido a contextos de alta informalidad. Típicamente, se han considerado dos metodologías para la ponderación vertical de las dimensiones de calidad: ad hoc y análisis de componentes principales. Este artículo analiza la calidad del empleo desde las preferencias de los trabajadores. Para ello se estudia el problema de ponderadores verticales como un problema de elección discreta que enfrenta el trabajador y que puede ser analizado con un modelo de betas estandarizados estimado por mínimos cuadrados ordinarios. Para ilustrar nuestra propuesta empleamos la información de la GEIH, para facilitar el ejercicio comparativo seguimos las ponderaciones horizontales presentadas por Farné (2003) y comparamos nuestro índice de calidad con las propuestas metodológicas previas. Encontramos que los trabajadores dan mayor ponderación en su orden a seguridad social, ingreso, contrato y horario laborales. Por otro lado, independientemente de la metodología, la calidad del empleo en el país es baja, con diferencias importantes entre asalariados en independientes, pero no entre hombres y mujeres.
Estimación de la productividad total factorial: un análisis de empresas del sector manufacturero en el Perú, 2002-2019
Authors:   Pontificia Universidad Católica de Perú, Tello Mario
Published: February 2025

Este artículo estima y realiza un análisis comparativo de cinco métodos de estimación de la productividad total factorial (PTF) de empresas de manufacturas del Perú, en el periodo 2002-2019. Estos métodos resuelven cuatro limitaciones de los estimados estándar MCO de la PTF: el de sesgo de simultaneidad, el sesgo de ‘attrition’ —o movimiento de firmas—, el sesgo debido a la omisión de los precios de los productos de las empresas, y la multicolinealidad entre los factores de producción. La principal base de datos para las estimaciones es la Encuesta Económica Anual de Empresas del INEI-EEA (2024). Los resultados que resaltan de las estimaciones son, por un lado, el incremento del índice promedio anual de la PTF de la muestra de empresas a una tasa de variación anual de 5% en el periodo 2003-2019. De otro lado, que la tasa de crecimiento de la PTF de las empresas está asociada a los términos de intercambio y en mucho menor medida a los acuerdos comerciales.
ADVANCED HEALTH ASSESSMENT OF HBA1C THROUGH NONPARAMETRIC REGRESSION: INVESTIGATING TG, FBS, BMI, TC, AND LDL INTERACTIONS
Authors: Hong Seng Fei , Ahmad Wan Muhamad Amir W , Adnan Mohamad Nasarudin , Noor Nor Farid Mohd , Ghazali Farah Muna Mohamad , Aleng Nor Azlida
Published: February 2025

This study evaluates the relationship between Hemoglobin A1c (HbA1c) and metabolic indicators – fasting blood sugar (FBS), triglycerides (TG), body mass index (BMI), total cholesterol (TC), and low-density lipoprotein (LDL) – using nonparametric regression techniques. HbA1c was modelled as the dependent variable, leveraging R Studio to capture complex non-linear interactions beyond traditional methods. A framework combining nonparametric regression and multilayer feedforward neural networks (MLFFNN) was constructed and validated. The dataset was split into training (70%) and testing (30%) sets, with performance metrics assessed via RMSE, MAE, RMSPE, and MedAE. The proposed method achieved high predictive accuracy, with RMSE and MAE of 0.0417 and MedAE of 95.83, demonstrating its robustness. This integration of statistical and machine learning methods offers a reliable tool for predicting HbA1c levels and emphasizes the potential of advanced analytics in healthcare.
La influencia de la obra de Jorge Manrique en Portugal, especialmente en el siglo XVI
Authors: Amaral Jr. Rubem
Published: February 2025

Fue muy honda, en el Portugal de fines del siglo XV y todo el siguiente, que corresponde al Renacimiento portugués, la influencia de las obras, además de otros escritores españoles, del poeta Jorge Manrique, con especialidad, pero no solo, de las famosas Coplas a la muerte de su padre, como se busca resaltar en este artículo. Tal tendencia fue estimulada por el gran prestigio de la cultura española, por el fenómeno del bilingüismo que caracterizó los círculos cortesanos e intelectuales de aquel país gracias a las frecuentes y estrechas relaciones de familia entre las dos casas reinantes, así como, finalmente, por la efímera unión de las dos coronas. Tal influencia penetró todas las manifestaciones literarias y se hizo sentir muy claramente en la producción de los más grandes poetas y dramaturgos lusitanos. Sin embargo, la huella manriqueña desaparece casi por completo de las letras portuguesas a partir de la recuperación de la independencia, que dió lugar a un largo divorcio político y cultural entre las dos naciones ibéricas.
Pasión por las relaciones de sucesos: Bibliofilia, bibliografía y documentación de casos
Authors: Gonzalo García Rosario Consuelo
Published: February 2025

En este artículo, se dan a conocer varias de las joyas bibliográficas que formaron parte de la biblioteca particular de Juan Pérez de Guzmán y Boza, duque de T’Serclaes de Tilly, y otras procedentes de la colección de Henry Huth. Se trata de relaciones de sucesos muy curiosas, contenidas en pliegos sueltos, de las que también se ha intentado reconstruir su historia textual, tipográfica y editorial, con el fin de mostrar las distintas vías de producción, transmisión y difusión de las noticias que circularon por Europa durante la Edad Moderna.
Los retos planteados por la edición de un codex unicus: la Relación de lo suscedido en la prisión del Rey de Francia de Gonzalo Fernández de Oviedo
Authors: Martín García Jorge
Published: February 2025

En principio, este artículo pretende dar cuenta de nuestro trabajo relacionado con la edición edición crítica de un texto aún sin publicar con criterios filológicos. Nos referimos a la obra del cronista Gonzalo Fernández de Oviedo titulada Relación de lo suscedido en la prisión del Rey de Francia. A partir de la descripción de nuestra labor, intentamos reflexionar acerca de las dificultades a las que se enfrenta el editor de un codex unicus. Asimismo, exponemos una serie de estrategias editoriales a nuestro alcance a partir de distintos lugares críticos del texto de Oviedo.
Reseña. Baltasar Gracián, El Héroe. Edición facsímil (Huesca, Juan Francisco de Larumbe, 1637). Prólogo de Aurora Egido, Zaragoza, Gobierno de Aragón e Institución Fernando el Católico, 2016
Authors: Jimeno Rodríguez Juan Antonio
Published: February 2025

Reseña de la edición facsimilar del ejemplar recuperado por la Biblioteca Nacional de España de la edición prínceps de El Héroe (1637) de Baltasar Gracián, perdida desde el siglo XVII. Esta publicación viene acompañada de un prólogo de la académica Aurora Egido, en el que exponen las principales aportaciones de este descubrimiento.
Reseña. Antonio Rey Hazas, Mariano de la Campa Gutiérrez y Esther Jiménez Pablo (Coords.), La Corte del Barroco. Textos literarios, avisos, manuales de corte, etiqueta y oratoria, Madrid, Polifemo, 2016. 735 páginas
Authors: Ruiz Astiz Javier
Published: February 2025

Reseña del libro: Antonio Rey Hazas, Mariano de la Campa Gutiérrez y Esther Jiménez Pablo (Coords.), La Corte del Barroco. Textos literarios, avisos, manuales de corte, etiqueta y oratoria, donde se recogen distintos estudios relacionados con la corte hispana en el siglo XVII elaborados por expertos de diferentes universidades.
Reseña. Rosario Consuelo Gonzalo García, El legado bibliográfico de Juan Pérez de Guzmán y Boza, duque de T'Serclaes de Tilly: aportaciones a un catálogo descriptivo de relaciones de sucesos (1501-1625). Madrid, editorial Arco/Libros, 2018
Authors: Ettinghausen Henry
Published: February 2025

Reseña de este libro, que analiza y da a conocer la rica colección de relaciones de sucesos particulares que reunió Juan Pérez de Guzmán y Boza, duque de T’Serclaes de Tilly (1852-1934). Su autora analiza la importancia bibliográfica e historiográfica de las relaciones de sucesos en la segunda mitad del siglo XIX, la figura del duque de T’Serclaes y su círculo intelectual. El libro detalla la metodología y conclusiones del estudio y ofrece un repertorio con descripción analítica de 285 noticias de ediciones de relaciones breves, redactadas tanto en prosa como en verso, escritas en castellano e impresas desde 1501 a 1625, dentro y fuera de la Península. Todas ellas se conservan actualmente en las tres bibliotecas particulares de herederos de T’Serclaes a las que la autora ha podido acceder. Añade calidad e interés a esta relación el hecho de acompañar cada noticia tipobibliográfica con la información relativa a la historia de su transmisión y difusión textual. El repertorio se convierte así en un valioso instrumento de consulta con el que poder afianzar el estudio de las formas de producción y difusión de los testimonios de este género editorial.
Reseña de: Anacreón castellano, de Francisco de Quevedo, edición crítica y anotada de Elena Gallego Moya y J. David Castro de Castro, A Coruña, SIELAE, 2018. ISBN 978-84-09-07700-7, 561 páginas
Authors: Izquierdo Adrián
Published: February 2025

Se realiza una reseña de la edición crítica y anotada del Anacreón castellano, de Francisco de Quevedo, publicada por el SIELAE (2018).
Abrazando el cambio:
Authors: Ardila Garcia Angie Katheryne , Velásquez Forero Luz Gisela
Published: February 2025

This article seeks to reflect on the importance of reinventing teachers in higher education environments and the way in which they can adapt to change and transform their pedagogical and didactic practices in order to make their work one that contributes to the different aspects of social, cultural and educational issues, understanding the challenges of today. For this, it is convenient to rescue the contributions of authors such as Ken Bain, Martha Nussbaum, Paulo Freire, Anna Forés and Esther Subias, who have promoted various approaches focused on the student, reflection, inclusion, equity, critical pedagogy and adaptation to the changing demands of higher education. All without forgetting that teaching and learning processes have undergone a transformation in the last decade, which has changed the way in which individuals access information, in which students learn and professors teach. The above perspectives could provide a basis for those teachers in training, active teachers and even university students who are interested in understanding the world of today's university teacher, the pedagogical strategies that should begin to be applied in higher education and the humanistic transformation in this context.
EXPLORING THE FACTORS AND MOTIVATIONAL ELEMENTS SHAPING THE SELF-REALISATION POTENTIAL OF TALENTED YOUTH
Authors: Redko Serhii , Sorokin Sergii , Perevozniuk Viktoriia , Viatokha Iryna , Shevchuk Viktoriia
Published: February 2025

The study's relevance is that self-realisation is one of the most important aspects of personality development, especially for gifted youth with the potential for significant achievements in various spheres of life. However, this potential often remains unrealised due to several psychological, social and motivational factors. In today's world, where rapid changes and high demands on young people are becoming the norm, research into these factors is particularly important to ensure adequate support and encouragement of gifted youth to achieve their personal and professional goals. The study focuses on gifted young people with the potential for significant achievements in scientific, creative, or professional activities. Particular emphasis is placed on this group's psychological characteristics, including their level of motivation, self-esteem, and stress resistance, as well as the role of external factors such as family support and social expectations. The study showed that most gifted young people have strong internal motivation, the primary driver of self-realisation. High self-esteem also contributes to self-confidence and the ability to overcome difficulties. However, some young people experience emotional pressure and high levels of stress due to social and internal expectations, which can prevent them from reaching their full potential. At the same time, family support is vital in reducing stressors and increasing psychological resilience.
Motivação e não sinonímia em gramática de construções: o caso das construções [se fazer de x] e [dar uma de x]
Authors: Bezerra de Carvalho Wallace , Borges Rua Robson , Oliveira Ramires Pinheiro Diogo , Leite de Oliveira Diego
Published: February 2025

Este trabalho tem como objetivo se debruçar sobre os Princípios da Motivação Maximizada e da Não Sinonímia (GOLDBERG, 1995) a partir da descrição e da análise das construções gramaticais “se fazer de X” e “dar uma de X”. Para tanto, este estudo parte de um viés funcionalista, tendo como aporte teórico principal os estudos relacionados à Gramática de Construções Baseada no Uso (HOFFMANN, 2022; AUTOR; PEREK, 2015; GOLDBERG, 2006). Para descrição e análise do objeto, lançamos mão dos corpora Corpus do Português e Corpus Brasileiro, de forma que tivéssemos acesso a dados reais de uso. Esta pesquisa, portanto, dados seu arcabouço teórico e sua metodologia, visa contribuir com os estudos das expressões idiomáticas do português brasileiro, bem como com o campo da Gramática de Construções Baseada-no-Uso.
Línguas e direitos linguísticos em Portugal: um panorama da legislação vigente
Authors: Figueira-Cardoso Samuel , Grzegorczyk Weronika , Marçalo Maria João
Published: February 2025

Este artigo discute a diversidade linguística e direitos linguísticos em Portugal. A análise centra-se na documentação oficial, como leis e decretos vigentes. É um estudo de natureza qualitativa de base bibliográfica e documental. O estudo procura responder como se apresenta a política de (co)oficialização e direitos linguísticos no país. Têm-se como objetivos: i) analisar a legislação vigente sobre o estatuto das línguas, direitos linguísticos e ações (políticas) do estado e dos falantes; ii) discutir a diversidade linguística, partindo da socio-história do falar e (algumas) particularidades das línguas oficializadas ou com algum direito previsto na legislação. A análise está centrada nas línguas: português, língua gestual portuguesa, mirandês e barranquenho. Concluímos que nas duas primeiras décadas do século XXI diversas iniciativas políticas em prol das línguas minoritárias e multilinguismo no país têm posto em pauta a promoção, preservação e (re)vitalização das línguas em Portugal, porém há uma emergência de investimento no ensino, produção escrita nas línguas oficializadas e financiamento de estudos científicos – em particular à contribuição dos estudos linguísticos.
Análise do valor semântico e variação linguística em provérbios e ditados populares brasileiros com chatgpt e antconc: um experimento
Authors: Pereira Barroso de Carvalho Dayane , Castiglioni Ana Claudia
Published: February 2025

Objetivamos investigar o valor semântico e a ocorrência de variação linguística em Unidades Fraseológicas (UF) do tipo Provérbios e Ditados Populares brasileiros, com a aplicação de Inteligência Artificial (IA) do tipo ChatGPT e software de processamento linguístico AntConc. Como referencial teórico, valemo-nos dos estudos de Klare (1986), Biderman (1998; 1987), Silva (2006), Xatara e Succi (2008), Monteiro-Platin (2014), entre outros. Os resultados demonstram haver potencial para utilização de IA e aprendizado de máquina em investigações sobre aspectos da linguagem. A avaliação sobre a adequação ou não desse tipo de tecnologia fica a critério do leitor. A respeito dos resultados linguísticos obtidos, observamos que há maior ocorrência de Provérbios e/ou Ditados Populares brasileiros incluídos nos campos semânticos de paciência (maior recorrência), precaução e prudência (segunda maior recorrência) e consequência (terceira maior recorrência). Além disso, foram identificadas variantes coocorrentes em diversos campos semânticos, incluindo paciência, precaução, consequência, comportamento, responsabilidade, comunicação e vulnerabilidade.
Generative AI-Powered Synthetic Data for Enhancing Predictive Analytics in Blood Donation Supply Management: A Comparative Study of Machine Learning Models
Authors: Hong Koh Chee , Ling Thong Chee , Kolandaisamy Raenu AL , Shibghatullah Abdul Samad Bin , Shahrol Nidzam Nazirul Nazrin Bin , Sarsam Samer , Zaman Halimah Badioze
Published: February 2025

Maintaining a sufficient and timely blood supply is an urgent and critical challenge in public health, where even minor miscalculations can lead to life-threatening shortages. This study evaluates the performance of machine learning models to improve blood donation forecasting. Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs) generated synthetic datasets that mirror real-world donation patterns to address data scarcity and variability issues. Leveraging transactional data from the Blood Bank Information System (BBISv2), a blood tracking system used by 22 main blood collection sites under the Ministry of Health (MoH) in Malaysia, 50 synthetic datasets were created and validated to ensure consistency with real data. The synthetic data showed minimal deviations from real data across key metrics, including mean (differences under 10%), variance (1 to 2 units), and skewness and kurtosis (0.03 or less). Among the models, the Random Forest algorithm demonstrated the highest performance, achieving an accuracy of 98.7%, a precision of 0.91, and an Area Under the Receiver Operating Characteristic (AUC-ROC) score of 0.92, making it the most reliable for predicting blood donation rates. Linear Regression also performed well, with an accuracy of 98.6%, while Neural Networks and Support Vector Machines (SVM) showed lower performance. This research provides a valuable tool for optimizing blood donation strategies, particularly in scenarios where real data is limited. Integrating validated synthetic data offers a novel approach for enhancing resource management in healthcare, ensuring reliable blood supply during high-demand periods.
USO DE CALDAS BIOFERTILIZANTES ALTERNATIVOS NA CULTURA DO MORANGO
Authors: Godinho Emmanuel Zullo , Beladeli Meirieli Nunes
Published: February 2025

O cultivo com uso de caldas biofertilizantes para uso áreas agrícolas familiares é de extrema importância para redução de custos de produção, além da produção de alimentos mais saudáveis e com menor impacto ao meio ambiente. Neste contexto, objetivo desta pesquisa foi avaliar o desenvolvimento do morango com a aplicação de caldas alternativas. Foram utilizados 2 tratamentos e uma testemunha, os tratamentos foram: calda de borra de café e calda de folhas de couve/beterraba/cenoura. O cultivar utilizado foi a San Andreas. Nas parcelas avaliou-se a altura da planta e o diamêtro do fruto. Para altura de planta não houve diferença significativa entre os tratamentos, entretanto para o diamêtro de pseudofruto o melhor resultado foi quando se aplicou a calda de borra de café com calda de folhas de couve/beterraba/cenoura e testemunha. Conclui-se que a aplicação de caldas alternativas como fertilizante afetaram consideravelmente a propagação vegetativa e a produtividade do morangueiro.
COMPOSIÇÃO QUÍMICA DE PLANTAS VISANDO A PRODUÇÃO DE RAÇÃO ALTERNATIVA PARA GALINHAS POEDEIRAS
Authors: Gêmero César Giordano , Silva Heloisa Pestana Mendes da , Selani Mirian Mabel , Duval Henrique Carmona
Published: February 2025

Este estudo objetivou determinar a composição química de plantas, a fim de desenvolver uma dieta alternativa para galinhas poedeiras. Amostras de folhas de ora-pro-nobis, leucena, moringa, mandioca, amendoim forrageiro e feijão guandu; grãos de feijão guandu e caruru; e sementes de leucena foram avaliadas quanto à umidade, matéria seca, matéria orgânica e inorgânica, lipídeo, proteína bruta, fibra bruta e extrativos não nitrogenados. As sementes de leucena se destacaram quanto ao teor de proteína, a folha de ora-pro-nobis em termos de cinza, a folha de feijão guandu e de moringa em relação ao teor de lipídeos e o caruru em termos de fibra bruta. Esses resultados são importantes para subsidiar futuras aplicações dessas plantas na formulação de rações alternativas, contribuindo para a produção de aves em sistemas agroecológicos.
Red Rice Bran Ethanol Extract Reduces IL-1β as the Risk of Pancreas Fibrogenesis in Type 2 Diabetic Rat Model
Authors: Wasita Brian , Yudhani Ratih Dewi , Pakha Dyonisa Nasirochmi , Nurrohima Diana , Muthmainah Muthmainah , Wiyono Nanang , Fakurazi Shariza
Published: February 2025

BACKGROUND: Oxidative stress and inflammation contribute to pancreatic cell dysfunction that promote insulin resistance in type 2 diabetes (T2D). Red rice bran contains bioactive substances with anti-inflammatory and antioxidant properties which improved insulin resistance in obese mice. However, no studies have explored the potential of ethanol extract of red rice bran (EERRB) to prevent T2D progression, particularly pancreatic fibrosis complications. This study was conducted to investigate the effect of EERRB on inflammation measured with interleukin (IL)-1β and fibrosis of pancreatic tissue in a rat model of T2D. METHODS: Rats were induced with streptozotocin and nicotinamide to induce diabetes, and then separated into five groups. One group received no treatment, while the other four received 9 mg/kg/day acarbose, 165, 330, or 660 mg/kg/day EERRB orally for 21 days. Immunohistochemistry was conducted on pancreas tissues to measure the expression of IL-1β, while pancreatic fibrosis was assessed with Masson’s Trichrome staining.RESULTS: EERRB reduced the expression of pro-inflammatory cytokine, IL-1β, in pancreas tissue in a dose dependent manner. Significantly lower IL-1β expression were found in group receiving 660 mg/kg/day EERRB (10%) compared to diabetic with no treatment group (50%) (p<0.0001). Additionally, the IL-1β expression in the highest dose of EERRB group was comparable to the group receiving acarbose (10%). CONCLUSION: This finding suggests the beneficial effect of EERRB in the hyperglycemic condition that causes oxidative stress through blocking the IL-1β expression, hence alleviating the inflammation in pancreas tissue, and have a tendency in preventing pancreatic fibrosis progression, a process implicated in T2D pathogenesis. KEYWORDS: diabetes, inflammation, pancreatic fibrosis, red rice bran
Utilização de cardiotocógrafo digital domiciliar wireless autoaplicado em gestantes de risco para parto prematuro
Authors: Lind Jolline , Loureiro Marcelo de Paula , Rocha Jaime Luis Lopes
Published: February 2025

Atualmente não existe consenso sobre a efetividade da monitorização domiciliar da frequência cardíaca fetal e contrações uterinas por meio de cardiotocografia autoaplicada em gestantes de risco para o parto prematuro, tal método é motivo de controvérsia, sendo necessárias pesquisas adicionais a fim de demonstrar seu real valor. Desta forma, objetivou-se avaliar a associação entre alterações na cardiotocografia digital móvel domiciliar wireless autoaplicada e o parto prematuro. Entre agosto de 2021 e julho de 2022, 75 gestantes com pelo menos um fator de risco para o parto prematuro foram submetidas à monitorização externa das contrações uterinas e frequência cardíaca fetal, a partir da 28ª semana até o parto, diariamente, durante 20 minutos, por meio de um cardiotocógrafo digital domiciliar wireless autoaplicado. O teste foi considerado positivo quando apresentou um resultado suspeito ou anormal pela Escala de Fischer. A incidência de partos prematuros foi de 16%. O método revelou uma sensibilidade de 81,82%, um valor negativo de 93,55% e uma AUC de 73,7%. Conclui-se que o teste negativo está associado a um baixo risco de nascimento prematuro. Contudo, diante de um teste positivo, torna-se necessária a associação com outros marcadores de parto prematuro para melhor identificar pacientes com risco elevado.
Growth and Productivity Improvement of Chickpea (Cicer arietinum L.) through Weed Management by Topramezone
Authors: Reddy Meka Shivaram , Ghosh Pritam , Sarkar Kader Ali , Kundu Manika
Published: February 2025

Background: Chickpea (Cicer arietinum L.) is the most important pulse crop widely cultivated for its nutritional and economic value. However, weed infestation poses a significant challenge to chickpea production, leading to reduced growth and productivity. Effective weed management strategies are therefore essential to mitigate the losses due to weeds and improve crop productivity. Selective herbicides with low or no phytotoxicity to the crop offer a promising solution for controlling weeds in order to boost up crop productivity. Currently available post emergence herbicides such as imazethapyr, can cause phytotoxic effects on chickpea. Therefore, it is essential to identify new post-emergence herbicides that can effectively control weeds without harming plant health. This study investigates the impact of topramezone, a selective post-emergence herbicide, on weeds as well as growth and productivity of chickpea. Methods: A field experiment was conducted at Agricultural Farm of Palli Siksha Bhavana, Visva-Bharati, Sriniketan during rabi season of 2021-22 and 2022-23. The experiment was laid out in randomized block design with nine treatments and three replications. The treatments were - T1 - topramezone 15 g ha-1 as POE, T2 - topramezone 17.5 g ha-1 as POE, T3 - topramezone 20 g ha-1 as POE, T4 - topramezone 22.5 g ha-1 as POE, T5 - topramezone 25 g ha-1 as POE, T6 - imazethapyr 60 g ha-1 as POE, T7 - pendimethalin 750 g ha-1 as PE, T8 - weed free and T9 - unweeded control. The study assessed the density and dry weight of weeds, weed control efficiency, growth and yield parameters as well as yield of chickpea under various application doses of topramezone in comparison with imazethapyr and pendimethalin. Result: Among all the herbicides, post-emergence application of topramezone 25 g ha-1 at 25 days after sowing resulted the lowest density and dry weight of weeds, the highest growth (plant height, LAI) and yield parameters (number of pods plant-1, number of seeds pod-1), seed yield and harvest index. Therefore, post-emergence application of topramezone 25 g ha-1 at 25 days after sowing proved to be an effective herbicide for weed control in chickpea in the lateritic belt of West Bengal.
Competitive Adsorption Mechanism of Mixed Gases in the Molecular Model of Hydrated Shale
Authors: Liu Jianyi , Wen Yimin , Yuan Hua , Liu Zhibin , Shui Zhengwei , Ba Yujiang , Gun Minjian , Pan Gongheng , Yang Yuzhong
Published: February 2025

Conducting the competitive adsorption mechanism of methane (CH4)/carbon dioxide (CO2) and the impact mechanism of water (H2O) is crucial for providing guidance for the evaluation of geological reserves in shale gas reservoirs and CO2 injection production. Therefore, based on the established heterogeneous shale molecular model, the competitive adsorption mechanism was simulated using molecular dynamics (MD) and grand canonical Monte Carlo (GCMC) simulation. Results revealed that, as CO2 content increased, CH4 adsorption capacity gradually decreased and adsorption capacity was gradually suppressed. When CO2 content increased to a certain value, the adsorption capacity of CH4 tended to approach equilibrium, indicating that shale has a stronger adsorption capacity for CO2. With the increase in H2O content, the adsorption capacity, adsorption rate, and saturation adsorption capacity of both CH4 and CO2 on shale decreased while reduction amplitude also decreased, indicating that an increase in H2O content in shale formations had a certain inhibitory effect. However, under high-pressure and high H2O content conditions, the influence of H2O on gas adsorption capacity decreased. Furthermore, the average isosteric adsorption heat range of CH4 in shale was 12.07–12.74 kJ/mol, while that for CO2 was 14.49–15.33 kJ/mol, indicating that the adsorption type of both gases in shale is physical.
The Unpredictable Business Environment in Cameroon: Delving into the Challenges Entrepreneurs Face Importing Goods and Exploring Potential Solutions
Authors: Kouam Arthur William Fodouop , Catche Fadila , Timba Gaëlle Tatiana
Published: February 2025

This study investigates the challenges faced by entrepreneurs in Cameroon, with a specific focus on the impact of fluctuating customs costs on their operations. Employing a mixed-methods approach that integrates both quantitative and qualitative analyses, the research includes a survey of 210 entrepreneurs across major urban centers and thematic interviews that provide in-depth insights. The findings reveal a robust positive correlation (β = 0.675, p < 0.001) between rising customs costs and operational challenges such as shipping delays and increased financial strain. A significant portion of entrepreneurs reported adapting through strategies such as supplier diversification and the adoption of digital tools, which were statistically linked to improved resilience in managing customs-related obstacles. Additionally, our analysis using Ordinary Least Squares (OLS) regression confirmed the importance of financial access as a moderating factor in dealing with customs costs. The study contributes to the existing literature by providing empirical insights into the interplay of customs costs and entrepreneurial resilience while offering practical solutions for policymakers to enhance the business climate in Cameroon, including the need for more transparent regulations and improved industry networking.
Characterization of the area to be used as a sanitary landfill in southeastern Brazil applying electrical resistivity and induced polarization methods
Authors: Jardim Roberta Layra Faragó , Pejon Osni José , Elis Vagner Roberto
Published: February 2025

The increase in municipal solid waste (MSW) generation observed over the years has sparked important discussions regarding its disposal. When MSW is disposed of in sanitary landfills, proper design according to current standards and constant monitoring can prevent environmental impacts. Geophysical methods have been used for subsurface characterization and contaminants monitoring, particularly geoelectrical methods, proving to be efficient and cost-effective. These indirect methods allow for a more comprehensive two-dimensional evaluation of the subsurface, which is impractical through direct surveys. This study aimed to demonstrate the efficiency of electrical resistivity and induced polarization methods in the characterization of MSW disposal areas. The study focused on the current sanitary landfill of São Carlos, Brazil, which was still under geological-geotechnical investigation at the time of the geophysical surveys. Electrical resistivity lines were conducted with a dipole-dipole array to investigate the physical properties of resistivity and chargeability. During the excavation of the first trench of the sanitary landfill in 2013, rock was identified at a shallow depth in a region where SPT results did not indicate the presence of rock at depths less than 17 meters. However, geoelectrical results revealed rocks at shallower depths. These results confirmed the potential of geoelectrical methods in identifying the diabase bedrock. The bedrock was delimited using resistivity profiles for values higher than 350 ohm.m. The chargeability profiles were employed as an auxiliary method to validate the results, showing increasing values with depth and resistivity.
Evaluation of Pre and Post-Emergence Herbicides: It’s Effect on Weed Dynamics, Yield, and Yield Components of Barley (Hordeum vulgare L.) in Awi Zone, Northwestern Ethiopia
Authors: Yilma Abebe , Wendaferew Demekech , Debebe Nardos , Abebaw Yekoye , Tilahun Yibeltal
Published: February 2025

Field experiments were conducted to evaluate different herbicides’ efficacy and their effect on yield and yield component of barley. Results of the experiment revealed that the dry weight of weeds, yield and most yield components of barley were significantly affected by the type of herbicides applied. Thus, the maximum weed dry weight of 206.7 gm-2 was recorded from the weedy check followed by plots treated with crop star 93.1gm-2 in Guagusa Shikudad. However, the least was obtained from plot treated with two times hand weeding (26.23 gm-2) in Banja district next to dry weight of weeds from the weed-free check (0.00gm-2). Besides, the maximum grain yield of 3238.9kg ha-1 and 3220kg ha-1, respectively was recorded from weed-free checks and plot received musket power treatment at Banja. The application of Musket power expressed the maximum marginal rate of return (174.61) and net benefit, reflecting effective management of weeds in barley.
Flexural behavior of concrete beam and slab with novel demountable connectors
Authors: Li Wei , Chen Wei , Jiang Huaming , Kong Zhengyi
Published: February 2025

In this study, a new type of novel demountable connectors is proposed to enable complete dry connections between concrete beams and slabs, facilitating the full demountable design of these components. To analyze and evaluate the flexural performance of the concrete beams with the novel demountable connectors, a finite element model is developed, which is then validated by previous tests. The results indicate that bolt diameter, bolt strength, channel spacing, and concrete slab thickness have a significant impact on peak load, while concrete beam strength, concrete slab strength, and flange width have minimal influence. Similarly, flexural stiffness is strongly affected by bolt diameter, channel spacing, concrete slab strength, slab thickness, and flange width, whereas bolt strength and concrete beam strength play a lesser role. Notably, the finite element analysis confirms the absence of plastic deformation in most bolts and end plates, ensuring that the flexural components are designed for effective disassembly. A theoretical model for calculating the ultimate flexural moment of demountable concrete beams under different conditions is also proposed, and it agrees with the ultimate flexural moment from numerical analysis.
An in silico journey of right ventricular growth and remodelling after pulmonary valve regurgitation
Authors: Gao Hao , Guan Debao , Danton Mark
Published: February 2025

Digital twins of cardiac function are revolutionizing the management of heart diseases. Pulmonary valve regurgitation (PR), a common complication following repair of tetralogy of Fallot, can lead to detrimental effects on right ventricular (RV) function if it persists. Although pulmonary valve replacement can address PR, its long-term effects remain a topic of debate. Despite the importance of RV in overall cardiac function, high-fidelity in-silico models of the right ventricle remain under-explored. In this study, we present a novel mathematical framework to simulate RV growth and remodelling in response to acute PR, along with long-term structural and functional adaptations, and reversible recovery post-intervention. We employ a subject-specific bi-ventricular model integrated with a lumped systemic circulation model, where myocardial mechanics are decomposed into passive and active components, and myocardial growth and remodelling are modelled through a kinematic approach with updated references constrained by biological limits. This framework allows us to model RV response to acute and chronic PR, and subsequent recovery following clinical intervention. For the first time, we demonstrate that RV pump function can return to normal if myocytes retain sufficient functional and structural reserve before interventions. This work marks a significant step toward the realization of digital twins of the RV, providing a robust, predictive tool for modelling disease progression, intervention outcomes, and myocardial reserve remodelling.
Vibrissa-inspired control of the orientation of an array of end-effectors
Authors: Galperin Mark , Kleczka Kevin , Hartmann Mitra
Published: February 2025

The ability to precisely orient an array of end-effectors is critical for applications in robotics, sensing, and engineering. Inspired by the vibrissal (whisker) system of rodents, we introduce a novel mechanism that controls an arbitrary number of rotating joints using a single mechanical input with three planar degrees of freedom. The system comprises two rigid frames – a fixed frame and a movable control frame – interconnected by stiff rods, enabling both forward/backward rotations (“protraction”) and converging/diverging rotations (“fanning”). We derive analytic expressions relating the control frame’s position and orientation to end-effector angles, proving that each configuration is associated with a unique parabola. We also show that a coordinate transformation allows independent control of protraction and fanning. Hardware implementation demonstrates that the mechanism is functional and that it can be scaled without additional actuators. This bio-inspired approach provides a versatile, low-dimensional solution for orienting sensors and tools in dynamic environments.
The Interplay Between IL-6, Hepcidin, and BMPR2 Signalling in Pulmonary Arterial Hypertension: Mechanistic Insights into Vascular Remodelling
Authors: Toe Quezia K , Issitt Theo , Quinlan Gregory J , Wort S John
Published: February 2025

Pulmonary arterial hypertension (PAH) is characterized by excessive pulmonary vasoconstriction and vascular remodelling, with mutations in bone morphogenetic protein receptor type 2 (BMPR2) being the most common genetic alteration associated with the disease. While inflammatory mediators like interleukin-6 (IL-6) and the iron-regulatory hormone hepcidin have been implicated in vascular remodelling, their interaction with BMPR2 signalling remains poorly understood. This study investigated how IL-6 and hepcidin influence BMPR2 expression and downstream signalling in human pulmonary arterial endothelial cells (hPAECs). Using qPCR and Western blot analyses, we demonstrated that both IL-6 and hepcidin significantly reduced BMPR2 mRNA and protein levels in hPAECs. Intriguingly, despite this reduction, SMAD1/5 phosphorylation remained active, suggesting compensatory signalling through alternative receptor complexes. Treatment with IL-6 and hepcidin upregulated inhibitors of differentiation (ID) protein expression, mimicking the effects observed with BMPR2 knockdown. These findings reveal a novel regulatory axis involving IL-6, hepcidin, and BMPR2 in PAH pathogenesis, where IL-6 and hepcidin promote vascular remodelling through both BMPR2-dependent and independent mechanisms. These results suggest that therapeutic strategies targeting this axis, particularly those aimed at rebalancing BMP/TGF-β signalling, may hold promise for treating PAH.