bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and antibiotic resistance pattern of extended spectrum beta lactamase producing Escherichia coli isolated from urinary tract infection
Authors: Rajabnia Mohsen , Forghani Mohammad Saad , Hasani Sabah , Bahadoram Mohammad , Mohammadi Mahsa , Barahman Maedeh
Published: June 2019

Introduction: Urinary tract infection (UTI) due to extended spectrum beta-lactamase (ESBL)-producing bacteria including Escherichia coli has become widespread. Studies have shown a trend toward higher mortality, longer hospitalization, greater hospital expenses and reduced rates of clinical and microbiologic response in ESBL UTI. Objectives: The aim of this study is to determinate the prevalence and antibiotic resistance pattern of ESBL producing E. coli isolated from UTI. Patients and Methods: This cross-sectional study was conducted on 3126 samples. Urine specimens were cultured on Eosin Methylene Blue (EBM) and blood agar. The disk diffusion standard method (Kirby Bauer) was used to test the susceptibility of the drug on MullerHinton agar plates and results were reviewed based on Clinical and Laboratory Standards Institute (CLSI) criteria. The reviewing of ESBL-producing uropathogens was carried out using Combined Disk Test (CDT) by using cefotaxime (CTX; 30 µg) and cefotaximeclavulanic acid (CTX; 30 µg /CA:10 µg) disks and CLSI protocol. Results: Out of 291 E. coli isolates, 108 (37.11%) are ESBL-producer and 183 (62.89%) are non–ESBL-producer. Among ESBL-producing E. coli, the highest antibiotic resistance was observed with cefotaxime (100%), amoxicillin (97.22%) and piperacillin (96.3%) and the highest antibiotic sensitivity was observed with meropenem (93.5%), nitrofurantoin (81.48%) and gentamicin (55.56%). Conclusion: We recommended that cephalosporins, penicillins and cotrimoxazole are not suggested in the treatment of ESBL-producing E. coli. On the other hand, carbapenems as a first line and aminoglycosides as the next step in the treatment of ESBL-producing E. coli are recommended.
Hepcidin in hemodialysis patients and its association with anemia and serum iron indices
Authors: Ghahramanfard Farahnaz , Yarmohamadi Maliheh , Ghorbani Raheb , Semnani Vahid , Mirzaei Arash , Ghushchian Chubmasgedi Maryam
Published: June 2019

Introduction: Anemia is one of the most common complications in dialysis patients. Deficiency of erythropoietin is the most common cause of anemia in dialysis patients. Chronic kidney disease (CKD) patients have a negative iron balance. Hepcidin is an antibacterial peptide that its synthesis is controlled by the iron surface and inflammatory markers and plays an important role in iron hemostasis in hemodialysis patients. In the presence of anemia, the level of hepcidin in normal individuals is reduced. Therefore, the normal level of hepcidin in CKD individuals is considered high due to their anemia level, while, the level of hepcidin is reduced after dialysis. Objectives: We aimed to study the level of hepcidin-25 in hemodialysis patients and its relationship with anemia and serum iron indices. Patients and Methods: In a cross-sectional study, 70 patients who fulfilled inclusion criteria enrolled in the study. Serum hepcidin 25 was measured by ELISA method. At the same time, blood samples were taken to measure other indices including iron, ferritin, C-reactive protein (CRP), total iron binding capacity (TIBC) and albumin. Hepcidin-25 levels compared with other mentioned parameters. Statistical analysis was done in SPSS 18.0 software. Results: No significant relationship between inflammatory cytokines, TIBC and CRP and erythrocyte sedimentation rate (ESR) with hepcidin levels was detected. Additionally, relationship between serum iron, ferritin and hepcidin levels was not significant (P > 0.05). Conclusion: Assessment of hepcidin 25 level for inflammation and iron status does not seem to be helpful for anemia management in hemodialysis patients.
Anna Amelina/Kenneth Horvath/Bruno Meeus (Eds.) (2016): An Anthology of Migration and Social Transformation. European Perspectives
Authors: Dahlvik Julia
Published: June 2019

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Cornelia Bruell/Monika Mokre (2018): Postmarxistisches Staatsverständnis
Authors: Marx Stefan A.
Published: June 2019

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Gert Krell/Peter Schlotter (2018): Weltbilder und Weltordnung: Einführung in die Theorie der Internationalen Beziehungen
Authors: Eder Franz
Published: June 2019

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Ludger Helms/David M. Wineroither (Hg.) (2017): Die österreichische Demokratie im internationalen Vergleich
Authors: Wassermann Heinz P.
Published: June 2019

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DSM-5 Alternative Model of Personality Disorder Dysfunctional Personality Traits as Predictors of Self-Reported Aggression in an Italian Sample of Consecutively Admitted, Personality-Disordered Psychotherapy Patients
Authors: Somma Antonella , Krueger Robert F. , Markon Kristian E. , Alajmo Valentina B. M. , Arlotta Emanuela , Beretta Stefano , Boni Francesca , Busso Stefano L. , Manini Riccardo , Nazzaro Giovanni , Maffei Cesare , Fossati Andrea
Published: June 2019

In order to assess the relationships between DSM-5 Alternative Model of Personality Disorder (AMPD) maladaptive personality traits and self-reports of aggression, 508 Italian adult participants who met at least one DSM-IV Axis II/DSM-5 Section II personality disorder (PD) diagnosis were administered the Personality Inventory for DSM-5 (PID-5) and the Aggression Questionnaire (AQ). Analysis results showed that multiple regression results, PID-5 Hostility, Callousness, and Risk Taking trait scale scores explained a large amount of variance in AQ Physical Aggression (PA) scores. Moreover, PID-5 Hostility, Callousness, and Risk Taking explained more than 20% of the variance in the AQ Physical Aggression scale scores that was left unexplained by selected continuously scored DSM-IV Axis II/ DSM-5 Section II PDs, whereas SCID-II Paranoid, Narcissistic, Borderline, and Antisocial PDs added only 4% of variance to the amount of variance in AQ Physical Aggression scores that was already explained by the PID-5 trait scale scores.
La mujer en la masonería madrileña entre 1869 y 1939
Authors: Según-Alonso Manuel
Published: June 2019

En el Madrid de finales del siglo XIX y primer tercio del siglo XX, en el marco del librepensamiento, el republicanismo y el discurso laicista, muchas mujeres buscan los principios de igualdad, fraternidad y libertad que la masonería defiende. A través de este trabajo, pretendemos recuperar la labor de masonería femenina madrileña y su contribución a la causa feminista, la emancipación de la mujer y al progreso. Trataré de recuperar el trabajo de todas las logias de Adopción y mixtas madrileñas, y el nombre de sus miembros.
SIMULASI DAYA DUKUNG LINGKUNGAN DI PULAU GILI KETAPANG – PROBOLINGGO DENGAN MENGANDALKAN CURAH HUJAN SEBAGAI PEMENUHAN KEBUTUHAN AIR
Authors: Ramdhan Muhammad , Husrin Semeidi , Pryambodo Dino Gunawan , Prihantono Joko , Nur Amri Syahrial , Prihatno Hari , Sudirman Nasir , - Hasanuddin , Iswahyudi Sachrul
Published: June 2019

Hujan merupakan salah satu sumberdaya air yang penting bagi kehidupan manusia. Keseimbangan lingkungan dapat diketahui dari ketersediaan sumber air yang berguna untuk memenuhi kebutuhan masyarakat. Daya dukung lingkungan adalah kemampuan lingkungan untuk menunjang kehidupan manusia dan makhluk hidup lainnya. Salah satu cara menentukan daya dukung lingkungan adalah dengan pendekatan ketersediaan dan kebutuhan air. Tujuan dari penelitian ini adalah melakukan simulasi terhadap status daya dukung lingkungan berdasarkan ketersediaan air bulanan dari curah hujan dan kebutuhan air di Pulau Gili Ketapang-Probolionggo dalam satu tahun. Metode yang digunakan untuk mengetahui daya dukung lingkungan adalah analisis kuantitatif melalui perbandingan antara penghitungan ketersediaan air dan kebutuhan air. Hasil penghitungan status daya dukung lingkungan berdasarkan ketersediaan air dan kebutuhan air di Gili Ketapang apabila dihitung berdasarkan kebutuhan layak air minum 130 liter/orang/hari adalah defisit sebesar 33.389.799,47 liter/bulan.
New Forms of Defining the Hidden Discrete Logarithm Problem
Authors: Moldovyan Alexandr , Moldovyan Nikolay
Published: June 2019

There are introduced novel variants of defining the discrete logarithm problem in a hidden group, which represents interest for constructing post-quantum cryptographic protocols and algorithms. This problem is formulated over finite associative algebras with non-commutative multiplication operation. In the known variant this problem, called congruent logarithm, is formulated as superposition of exponentiation operation and automorphic mapping of the algebra that is a finite non-commutative ring. Earlier it has been shown that congruent logarithm problem defined in the finite quaternion algebra can be reduced to discrete logarithm in the finite field that is an extension of the field over which the quaternion algebra is defined. Therefore further investigations of the congruent logarithm problem as primitive of the post-quantum cryptoschemes should be carried out in direction of finding new its carriers. The present paper introduces novel associative algebras possessing significantly different properties than quaternion algebra, in particular they contain no global unit. This difference had demanded a new definition of the discrete logarithm problem in a hidden group, which is different from the congruent logarithm. There are proposed several variants of such definition, in which it is used the notion of the local unite. There are considered right, left, and bi-side local unites. Two general methods for constructing the finite associative algebras with non-commutative multiplication operation are proposed. The first method relates to defining the algebras having dimension value equal to a natural number m > 1, and the second one relates to defining the algebras having arbitrary even dimensions. For the first time the digital signature algorithms based on computational difficulty of the discrete logarithm problem in a hidden group have been proposed.
Towards Design of Quasilinear Gurvits Control Systems
Authors: Gaiduk Anatoly
Published: June 2019

The design problem of control systems for nonlinear plants with differentiated nonlinearity is considered. The urgency of this problem is caused by the big difficulties of practical design of nonlinear control systems with the help of the majority of known methods. In many cases, even provision by these methods of just stability of equilibrium point of a designing system represents a big challenge. Distinctive feature of the method of nonlinear control systems design considered below is the use of the nonlinear plants models represented in a quasilinear form. This form of the nonlinear differential equations exists, if nonlinearities in their right parts are differentiated across all arguments. The quasilinear model of the controlled plant allows reducing the design problem to the solution of an algebraic equations system, which has the unique solution if the plant is controlled according to the controllability condition provided in the article. This condition is similar to the controllability condition of the Kalman’s criterion. Procedure of the nonlinear control systems design on a basis of the plant’s quasilinear models is very simple. Practically, it is close to the known polynomial method of the linear control systems design. The equations of the nonlinear systems designed with application of the plant’s quasilinear models also can be represented in the quasilinear form.

The basic result of this article is the proof of the theorem and the corollary from it about conditions of the asymptotical stability at whole of the equilibrium point of the nonlinear control systems designed on a basis of the plant’s quasilinear models. For the proof of the theorem and consequence, the properties of simple matrixes and known theorems of stability of the indignant systems of the differential equations are used. A way of the stability research of the equilibrium point of the quasilinear control systems based on the proved theorem is illustrated by numerical examples. Computer simulation of these systems verifies correctness of the hypoyhesis of the proved theorem.

Obtained results allow applying the method of nonlinear systems design on a basis of the quasilinear models for creation of various control systems for plants in power, aviation, space, robotechnical and other industries.
Immediate Insertion of Dental Implants Immediate Insertion in Bilateral Traumatic Bone Cysts With or Without a Bone Grafting Material: A 5-Year Follow-Up Case Report
Authors: Palma Vinicius Canavarros , da Silva Caetano Rafael , Borges Alvaro Henrique , Volpato Luiz Evaristo Ricci
Published: June 2019

This case report describes the rehabilitation of a patient who received dental implants in traumatic bone cyst areas (TBC). A 24-year-old male patient sought dental treatment for the bilateral absence of the mandibular second premolars. Radiographic examination revealed bilateral large radiolucent images in the mandible body. Surgical exploration confirmed the diagnosis of TBC. Rehabilitation with dental implants was performed using different approaches on each side. One cystic cavity was filled with blood clot and allogenic bone graft; the other was filled only with blood clot. After 5 years, the implants are osseointegrated and functioning. The filling of the traumatic bone cyst cavity with local blood clot in contact with the implant presented clinical and radiographic success similar to that obtained with filling with bone graft in the same patient. Thus, in this patient, the blood clot-only approach can be considered as a viable, safe-low cost alternative to blood clot and grafting material.
“The 2-Dimensional Approach”: a novel tool to help learners organize their knowledge and improve their clinical reasoning skills.
Authors: Shimozono Hisashi , Takahashi Makoto , Tomita Makoto , Takada Kazuki , Tanaka Yujiro
Published: June 2019

This article was migrated. The article was marked as recommended. Background: Clinical reasoning is an essential competence of a physician. Particularly, pathophysiological understanding is the key for novices to organize their knowledge and improve clinical reasoning. To this end, we propose a "2-Dimensional (2D) Approach" that visualizes pathophysiology by using a matrix of organs and systems. Methods: This study was a prospective observational study of 100 residents (PGY-1), who attended a lecture on the 2D Approach. They underwent a pre- and post-test that assessed their ability to list differentials for various symptoms and to choose the most likely diagnosis for a case vignette. We stratified the participants according to their baseline knowledge level on the pretest into 2 groups (high-knowledge and low-knowledge). In each of the 2 groups, we compared the change in the pre- and post-test scores between participants who used the 2D Approach during the posttest and those who did not. Results: In the high-knowledge group (n=59), the change in the pre- and post-test scores was significantly larger in the 2D Approach users than non-users (p=0.046), while in the low-knowledge group (n=41), there was no significant difference in the change of the scores between the 2D Approach users and non-users. Conclusions: On condition that residents have sufficient knowledge, the 2D Approach helps them organize their knowledge and improve their clinical reasoning skills, through visualization of pathophysiology on a matrix of organs and systems.
Introduction
Authors: Crag Hill  , Leilya Pitre  , Steven Bickmore  , Gardner Catlin
Published: June 2019

Welcome to Study and Scrutiny: Research on Young Adult Literature, Volume 3/Issue 2.
Silicon wafer strain under local photonic annealing
Authors: Starkov V. V. , Gosteva E. A. , Irzhak D. V. , Roshchupkin D. V.
Published: June 2019

The effect of photon annealing on the occurrence of deformations in the crystal structure of boron−doped silicon wafers produced by the Czochralski (Cz−Si) was studied by the method of triple−X−ray diffraction. It was found that the traditional annealing of silicon wafers with polished surfaces on both sides by halogen lamps in Photonic Annealing (PA) and rapid thermal annealing modes (RTA) leads to compression deformation. The same process with the use of original photo− mask, which allows local processing produces multiple, spatially separated regions of the plate produced by Lосаl Photonic Annealing (LPA) at relatively low temperatures (less than 55 °C), gives rise to a tensile strain. This established effect is not observed if on the back side of the plates there is mechanical gettering layer. The mechanism explaining the experimental results can be used in the formation of the charge pump in the structure of the photo electric converters (PEC).
The development of the market and the production technology of polycrystalline silicon
Authors: Mitin V. V. , Kokh A. A.
Published: June 2019

The article is devoted to the current state and prospects of production development of main material — polycrystalline silicon (polysilicon) which is used in the manufacture of products for micro and power electronics and photovoltaics. The article includes polycrystalline silicon market dynamics analysis. It is noted that the increase in polysilicon output is primarily connected to the growing needs of photovoltaics and the global trend of transition to renewable, alternative energy. It is assumed that the annual increase in the output of polysilicon will reach a level of 10−15 % or more. There are several facts that are important for the intensive development of photovoltaics. They include level of polycrystalline silicon technology and the availability of this material for large−scale production of highly efficient solar cells. According to forecasts, the main technology used in the industry based on «Siemens Process» will remain dominant in the foreseeable period of time. LLC «Kremniytehnoprom» is developing a modern polysilicon production project based on the original designs and modernization of «Siemens Process». It is planned to be created in Russia with the involvement of leading German specialists and enterprises (SPSC GmbH, GEC GmbH). The project provides maximum safety of production, despite the potential risks inherent in technology. First of all it is ensured by guarantees of hardware−technological schemes performance, reliability of the equipment and design solutions in general, as well as by a set of emergency protections. Toxic production waste will be processed into safe substances — targeted products for sale. The created enterprise will ensure the optimization of key indicators for competitive production: the price of polysilicon, production volumes, specific capital investments and current unit costs.
EL IMPACTO DE LA EDUCACIÓN EN LA INTENCIÓN EMPRENDEDORA DE LOS ESTUDIANTES DEL GRADO DE ECONOMÍA
Authors: SUAREZ MACARENA PEREZ , Sanchez Torné Isadora
Published: June 2019

Este trabajo tuvo como objetivo conocer la incidencia de la formación sobre Creación de empresas, una asignatura obligatoria, en estudiantes del grado en Economía desde una perspectiva de género. Con tal fin, se analizó, a partir de la Teoría del Comportamiento Planificado, las intenciones, actitudes y capacidades emprendedoras del alumnado que asistió a la citada asignatura durante cinco cursos académicos (un total de 272 respuestas). Bajo un método científico inductivo (inferencias y correlaciones) se observó a la misma población antes y después de la formación. Consecuentemente, se aplicó una serie de pruebas estadísticas para conocer si existen diferencias significativas ex−ante y ex−post formación. Como resultado se identificó el perfil estándar del alumnado de cuarto curso del grado Economía de la Universidad de Sevilla (mujer con edad media de 22 años), así como, una serie de premisas sobre pretensiones, actitudes y capacidades emprendedoras. Las principales derivaciones fueron que: aumenta la proporción de personas estudiantes que declara tener una idea para crear una empresa; mejora significativamente la valoración de los conocimientos para crear y dirigir una empresa, además de muchas de las competencias transversales. Sin embargo, la intención y actitud emprendedora se redujo significativamente. Por último, se observó que la educación emprendedora tuvo un mayor efecto en las mujeres que en los hombres, concretamente, ellas aumentaron su valoración en más capacidades empresariales y comportamiento percibido, a pesar de que la intención emprendedora fue superior en ellos. La educación emprendedora es un medio de reducir esa diferencia debiendo incorporar modelos de referencia femeninos.
PLANTEAMIENTO DE UN MODELO DE EVALUACIÓN DE LEAN SUPPLY CHAIN MANAGEMENT
Authors: García Buendía Noelia , Moyano Fuentes José , Maqueira Marín Juan Manuel
Published: June 2019

En este trabajo se plantea un modelo de evaluación de la gestión lean en la cadena de suministro, a partir de los indicadores de resultados más utilizados en la literatura. Se parte de una Revisión Sistemática de la Literatura realizada con anterioridad por los autores, para identificar los indicadores que más consenso han recibido, y se realiza una clasificación en función de la naturaleza de los mismos, según si es operativa, financiera o de mercado. Este modelo tiene como finalidad servir de fundamento para la elaboración de un Cuadro de Mando. De este modo, se propone un modelo teórico para evaluar los resultados derivados de la gestión lean de la cadena de suministro, agrupando los indicadores en enfoques o perspectivas de interés para que los directivos puedan orientar su toma de decisiones, de forma similar a un cuadro de mando integral.
GENDER AND RACE IN THE OCCUPY MOVEMENT: RELATIONAL LEADERSHIP AND DISCRIMINATORY RESISTANCE
Authors: Hurwitz Heather McKee
Published: June 2019

When social movement leaders direct protesters during marches or make decisions during meetings, followers accept and validate, or oppose and ignore them. Yet most leadership theories neither account for follower responses nor explain how followers' expectations about gender and race status-hierarchies influence their actions. Drawing on participant observation, an archive of movement documents, and 73 in-depth interviews with key informants in the occupy movement, I reveal how followers enacted forms of “discriminatory resistance” that impeded women and genderqueer persons' leadership. I argue that followers fell back on gender and racial stereotypes about white men as ideal leaders. Followers opposed women and genderqueer persons from all races and ethnicities using harassment and male dominance, and by creating a hostile culture. Findings suggest that even leaders and followers in nonhierarchical social movements construct gender and race differences in leadership similar to leadership stratification in more hierarchical organizations.
HIGH- AND LOW-RISK ACTIVISM: DIFFERENTIAL PARTICIPATION IN A REFUGEE SOLIDARITY MOVEMENT
Authors: Gundelach Peter , Toubøl Jonas
Published: June 2019

This article presents a quantitative study of differential participation in low- and high-risk activism in the Danish refugee solidarity movement. Distinguishing between low- and high-risk activism, it shows the fruitfulness of combining what are often considered competing theoretical explanations related to (1) values, (2) microstructures, and (3) emotions. We analyze data from a unique survey of 1,856 respondents recruited via Facebook. The results show that low- and high-risk participation strongly correlate but are influenced by different factors. For low-risk activities, the most important factors are emotional reactions, structural availability, and predispositions in the form of basic human values. For high-risk activity, the important factors are prior history of activism and emotional reaction. Values, microstructures, and emotions interact in relation to participation in both kinds of activism, which points to promising avenues for integrating and developing the theoretical framework of differential participation and recruitment.
Role of C807T polymorphism of ITGA2 gene of collagen receptor and platelet aggregation activity in patients with arterial hypertension
Authors: Shishkina E A , Khlynova O V , Vasilets L M , Sakhena V , Krivtsov A V
Published: June 2019

Aim. To study the prevalence of various C807T polymorphism variants of the ITGA2 gene and to analyze the association of this polymorphism with platelet aggregation activity in hypertensive patients.

Methods. 47 patients with arterial hypertension treated at the Clinical Cardiology Dispensary (Perm) were included in the study. Genotyping of C807T polymorphism (rs 1126643) was carried out by the method of polymerase chain reaction with the subsequent identification of the single nucleotide polymorphic variant of ITGA2 gene by the method of allele-specific polymerase chain reaction. Platelet aggregation activity was investigated by the impedance method using TRAP-6 reagent as an inducer of aggregation.

Results. The prevalence of C/C, C/T, T/T genotypes of ITGA2 gene among hypertensive patients was 18 (38.3%), 23 (48.9%) and 6 (12.8%), respectively. A comparative analysis of platelet aggregation activity with TRAP-6 reagent revealed statistically significant differences between the groups of patients carrying different genotypes [103.5 (67.0; 121.0) AU in homozygotes –807CC versus 52.5 (48; 83) AU in homozygotes –807TT, p=0.045]. In the group of patients with reduced platelet aggregation activity (TRAP-test less than 94 AU), the carriage of the unfavorable T allele prevailed in comparison with the group of patients with its normal level (OR=3.81, 95% CI 1.38–10.54; p=0.008). In patients of this group, there was a significant increase in the frequency of occurrence of heterozygotes –807CT (OR=4.75, 95% CI 1.24–18.19; p=0.009), as well as an increase in the frequency of occurrence of homozygotes for the variant allele -807TT (OR=2.88, 95% CI 0.31–27.07; p=0.009) compared with the group of patients with a normal level of aggregation.

Conclusion. The prevalence of C/C, C/T, T/T genotypes of ITGA2 gene among patients with arterial hypertension is comparable to the data of European researchers: carriers of T allele of ITGA2 gene may have a higher risk of developing cardiovascular events; the molecular mechanism of the relationship of reduced platelet aggregation activity and carriage of the unfavorable T allele of ITGA2 gene requires further studies.
Effect of Leu-Ile-Lys tripeptide on the activity of free radical oxidation and expression of сyclooxygenase-1 and -2 in gastric mucosa in experimental indomethacin-induced ulcer in rats
Authors: Lorents S E , Mazko E N , Makarova O G , Zharikov A Yu , Korenovskiy Yu V , Azarova O V
Published: June 2019

Aim. To determine the effect of Leu-Ile-Lys tripeptide on indicators of oxidative stress and expression of cyclooxygenase-1 and -2 in the gastric mucosa on the background of experimental indomethacin-induced ulcer.

Methods. Experiments were performed on 35 male Wistar rats with a body mass of 200-250 g aged 2-3 months that were divided into 3 groups: the control group (intact rats, 8 animals), control group (simulation of indomethacin-induced gastropathy, 12 animals) experimental group (simulation of indomethacin-induced gastropathy + administration of Leu-Ile-Lys tripeptide, 15 animals). The tripeptide Leu-Ile-Lys obtained by chemical synthesis (sample purity at least 98%) was administered intragastrically daily for 7 days before the simulation of indomethacin-induced damage of the gastric mucosa in a dose of 11.5 mg/kg. The model of indomethacin-induced damage to the rodent gastric mucosa was reproduced by a single intragastric administration of indomethacin in a dose of 60 mg/kg in 1 ml of saline. In the stomach homogenate the activity of free radical oxidation was determined by conventional methods. For quantitative determination of cyclooxygenase-1, -2 in gastric homogenate the method of enzyme immunoassay was used. The concentration was determined spectrometrically by the color intensity of the samples.

Results. With a prophylactic administration of tripeptide Leu-Ile-Lys, concentration of tiobarbiturate-reactive products was normalized, total antioxidant activity increased and the activity of antioxidant enzymes decreased compared to the control group. The concentration of cyclooxygenase-2 in gastric homogenate from the experimental animals was 2.3 times lower than that of the control rats.

Conclusion. Use of Leu-Ile-Lys tripeptide in experimental indomethacin-induced gastric ulcer showed a significant decrease of oxidative damage and inflammation in the gastric mucosa.
Implantation of a trifocal toric intraocular lens to a patient with pigment dispersion syndrome
Authors: Akhmetshin R F , Gilyazev M R , Galeeva A T , Bulgar S N
Published: June 2019

Aim. To present a clinical case of treatment of pigment dispersion syndrome by clear lens extraction and implantation of a toric intraocular lens in a patient with myopic astigmatism.

Methods. A 33-year-old patient with a diagnosis of moderate myopia, complex mild myopic astigmatism, pigment dispersion syndrome of both eyes.

Results. The first stage was laser peripheral iridotomy of both eyes. On follow-up pathological irido-zonular contact and increases intraocular pressure by 2 mm persisted. The second stage included clear lens extraction and implantation of a toric multifocal intraocular lens to both eyes. In 2 months, distance and near visual acuity was 1.0, intraocular pressure was normal, no pathological irido-zonular contact was observed according to the ultrasound biomicroscopy.

Conclusion. Implantation of an intraocular lens in patients with myopia and pigment dispersion syndrome is both a method of preventing pigment glaucoma and myopia correction; patients with pigment dispersion syndrome after peripheral iridotomy should monitor the state of the anterior segment of the eye and the effectiveness of the treatment by ultrasound biomicroscopy.
'Alexia', de Samuel Rosa e Nando Reis [áudio]
Authors: FuLiA / UFMG Revista
Published: June 2019

Música "Alexia", de Samuel Rosa e Nando Reis, gravada no disco Velocia (2014), do grupo mineiro Skank, composta em homenagem ao belíssimo gol da jogadora Alexia Putellas pelo Barcelona. Conf.: (https://www.youtube.com/watch?v=II36vAKsiF4).
Futebol e mulheres [imagem]
Authors: Kfouri Daniel
Published: June 2019

A seção Poética apresenta a série composta por nove imagens, de Daniel Kfouri, produzidas para o Coletivo Guerreiras Project, em 2014. As fotografias fizeram parte da exposição “Futebol e mulheres no país da Copa”, realizada na Usina do Gasômetro, em Porto Alegre, ao longo da Copa do Mundo FIFA 2014.O artista visual é filho de Juca Kfouri, um dos maiores jornalistas esportivos do Brasil e pensador da cultura sócio-futebolística, o que certamente influenciou a singular maneira de Daniel olhar o mundo, pois publicou algumas séries sobre o esporte com um foco sensível às performatividades marginalizadas: Mais que uma medalha, imagens das Paralimpíadas Rio 2016, Campo dos sonhos, que recai sobre o polo aquático, Mulheres de areia, mostrando o futebol de areia praticado por mulheres, e Várzea, sobre o futebol na periferia. Além das séries que homenageiam Neymar e o Corinthians: Magrelo 2009-17 e Não para, respectivamente.
O Estatuto da FIFA e a igualdade de gênero no futebol: histórias e contextos do Futebol Feminino no Brasil
Authors: Almeida Caroline Soares de
Published: June 2019

Este ensaio procura analisar as mudanças ocorridas no Futebol Feminino brasileiro a partir da introdução da igualdade de gênero no estatuto da FIFA, em 2016. Depois de anos de banimentos e exclusões, ações para o fortalecimento do Futebol Feminino – e de mulheres que atuam como profissionais na área – ganharam certo espaço na agenda da CBF. No entanto, a disparidade existente nas relações de gênero, no contexto futebolístico nacional, mostrou-se bastante latente em pouco tempo. Para tanto, apresento uma reflexão sobre os relatos observados durante o trabalho de campo – realizado no interior do estado de São Paulo – e as notícias publicadas em diferentes veículos de comunicação sobre essa temática.
Realistyczna interpretacja domniemanego idealizmu G. Berkeleya
Authors: Mordka Cezary
Published: June 2019

W artykule przedstawiam próbę wskazania na to, iż dokonania Berkeleya, mimo rzekomego konsensusu, nie dają się umiejscowić w obszarze idealizmu subiektywnego. Niezależnie od sformułowań samego Berkeleya, który nie pozostawał klarowny semantycznie, daje się utrzymać tezę, iż świat nie utracił dla niego pozycji bytu realnego, tyle że realność tego świata całkowicie była uzależniona od aktywności bytu boskiego. Filozof słusznie zwrócił uwagę na nieodzowność podmiotowych ujęć w kwestii dostępu do świata. Nie mając odpowiedniej ontologii dla idei, Berkeley nie był w stanie „oderwać” idei od umysłu, lecz znaczyło to u niego „bycie dla umysłu”.

 

 
¿Qué actitudes hacia la ciencia posee el alumnado de Educación Primaria que participa en actividades científicas extracurriculares?
Authors: Toma Radu Bogdan , Ortiz-Revilla Jairo , Greca Ileana M.
Published: June 2019

La necesidad de impulsar la alfabetización científica desde edades tempranas y el generalizado descenso del interés por seguir carreras científico-tecnológicas representan algunas de las principales problemáticas de la investigación en Didáctica de las Ciencias. En este estudio se evalúan las actitudes hacia la ciencia de 960 estudiantes de 3º a 6º curso de Educación Primaria que asisten a actividades extracurriculares de ciencias. Los resultados muestran que, en general, estos estudiantes poseen actitudes favorables hacia la ciencia, sin embargo, su entusiasmo por la ciencia y sus actitudes hacia las clases de Ciencias de la Naturaleza descienden con el aumento del nivel escolar. La diferencia entre las actitudes de niños y niñas no es tan marcada como en la literatura existente, identificándose inclusive que las niñas poseen actitudes más positivas hacia los científicos. Estos resultados subrayan la necesidad de tomar medidas educativas enfocadas a prevenir el descenso de las actitudes de los estudiantes desde los cursos elementales del sistema educativo.
Propuesta didáctica en la formación de profesorado para trabajar naturaleza de la ciencia y pensamiento crítico
Authors: Cobo Huesa Cristina , Abril Gallego Ana María , Romero Ariza Marta
Published: June 2019

La demanda social de educar a ciudadanos alfabetizados científicamente convierte en prioritario formar a profesorado con una adecuada comprensión sobre la naturaleza de la ciencia (NDC) y desarrollo de pensamiento crítico (PC), requisitos indispensables para poder impartir dichos contenidos en el aula. Para tal fin, en este trabajo, se presenta el diseño de una propuesta didáctica (prototipo), que está siendo evaluada y mejorada a través de la metodología de investigación enfocada al diseño. Este prototipo integra la indagación y la historia de la ciencia a través de la controversia científica de la generación espontánea, dentro de un marco explícito-reflexivo. Con el fin de mejorar su diseño y eficacia, se están llevando a cabo ciclos iterativos de pilotaje que, hasta el momento, han mostrado la importancia de adoptar un enfoque guiado en las tareas de indagación y de un enfoque explícito en la instrucción sobre la NDC y el PC para lograr un aprendizaje exitoso y significativo.
Investigation of NMDA Receptor Channel Blockers in a Series of Methylene Blue Conjugates Using QSAR and Molecular Modeling
Authors: Grigorev V.Y. , Shcherbakov K.A. , Polianczyk D.E. , Razdolsky А.N. , Veselovsky A.V. , Grigoriev V.V. , Yarkov A.V. , Raevsky О.А.
Published: June 2019

29 conjugates of methylene blue and four chemical structures, including derivatives of carbazole, tetrahydrocarbazole, substituted indoles and γ-carboline, combined with a 1-oxopropylene spacer have been studied as channel blockers of the NMDA receptor (binding site of MK-801) by using four QSAR methods (multiple linear regression, random forest, support vector machine, Gaussian process) and molecular docking. QSAR models have satisfactory characteristics. The analysis of regression models at the statistical level revealed an important role of the hydrogen bond in the complex formation. This was also confirmed by the study of modeled by docking complexes. It was found that the increase in the inhibitory activity of the part of compounds could be attributed to appearance of additional H bonds between the ligands and the receptor.
A Simplified Method for Obtaining cDNA of Low-Copy and Silent Eukaryotic Genes Using Human Renalase as an the Example
Authors: Fedchenko V.I. , Kaloshin A.A.
Published: June 2019

A simplified «exon» method was developed for producing cDNA of low-copy and silent eukaryotic genes. It is based on assembly of the target gene from genomic DNA by direct synthesis of its exons, followed by their PCR-based joining without further purification of the amplicons. During the synthesis of exons, direct primers were used; these included about ~ 20 nucleotides of the 3`-terminal sequence previous (from the amplified) exon and ~ 20 nucleotides of the 5`-initial sequence of the amplified exon. Reverse primers included ~ 20 nucleotides complementary to the terminal sequence of the amplified exon. Forward and reverse primers flanking the gene to be assembled included the restriction sites necessary for insertion into the expression vector. Using this approach it is possible to assemble almost any eukaryotic gene with a known nucleotide sequence of genomic DNA available in the database.
Le concept du fragmentaire dans le Journal d’Henriette Dessaulles
Authors: Vadean Mirella
Published: June 2019

Cet article met en évidence l’importance de l’analyse heuristique du fragment, fonction d’une esthétique représentative du continuum. Inclassable dans le cadre d’un genre, le fragment entretient une relation de dépendance et d’indépendance avec le Système (le Tout). En opérant une distinction entre la discontinuité et le fragment, nous saisissons dans le Journal d’Henriette Dessaulles une « exigence de la parole fragmentaire » nécessaire pour composer à partir du Décomposé et pour admettre à partir du Refus. Notre réflexion est articulée autour de deux axes : les obstacles du fragmentaire et le fragment comme praxis intentionnelle.AbstractThis paper emphasizes the importance of the heuristic analysis of the fragment as a function of an aesthetic representative of the continuum. Impossible to be classified as a type, the fragment maintains both a relationship of dependence and independence with the System (The Whole). By making a distinction between discontinuity and the fragment, we observe in the Henriette Dessaulles’ diary a "requirement of the fragmentary speech" which is necessary to compose starting from Decomposed and to admit starting from the Refusal. We organize our interpretation according to two axes: the obstacles of the fragmentary and the fragment as intentional praxis.
L’Afrique de Pétrarque et la bataille des lettres à la Renaissance
Authors: Bouchard Mawy
Published: June 2019

On propose ici une réflexion sur la nature du travail poétique de Pétrarque dans son poème narratif L’Afrique, resté inachevé. À travers les voix de grands guerriers et de poètes qui en ont assuré la gloire, Pétrarque expose en effet sa conception de la narration digne de traverser les siècles en des termes qui ne correspondent pas tout à fait aux balises esthétiques de la poétique. Le grand poète toscan développe plutôt une éthique de l’écriture qui accorde la plus grande légitimité à la poésie « vraie ». Au fil des livres de L’Afrique, la prépondérance des lettres en général et de la poésie en particulier sur les autres compétences humaines constitue un leitmotiv qui allait devenir emblématique de la renaissance des lettres européennes.AbstractThis paper examines the poetics of Petrarca’s unfinished epic Africa. Through the voices of two great warriors and those of poets who have sung their praises, Petrarca exposes his conception of the worthy — that is the ethical — narrative. Indeed, the Tuscan poet develops an ethics of writing and strives to institute a poetry of ‘truth’. Throughout Africa, the preponderance of letters in general and of poetry in particular constitutes a leitmotiv that was to become emblematic of Renaissance literature.
L’écriture biblique dans la littérature du XIXe siècle finissant : le cas de Strindberg
Authors: Cedergren Mickaëlle
Published: June 2019

Inferno constitue une plaque tournante dans la production littéraire de Strindberg. Les citations bibliques apparaissent plus fréquemment et créent un nouveau style d’écriture. Cet article présente les caractéristiques textuelles du discours biblique dans Inferno (1897) et Jacob lutte (fragment écrit à la suite de Légendes en français et en suédois en 1898). L’analyse linguistique, dans laquelle sont incluses des approches comparative, discursive, textuelle et intertextuelle, va définir la place et le rôle stratégique de la citation biblique dans ce corpus littéraire. Finalement, trois jeux d’écriture biblique ressortent de cette étude et dévoilent à tour de rôle la disposition et l’évolution spirituelle du narrateur dans chaque texte.AbstractInferno constitutes a turning point in Strindberg’s literary production in that scriptural quotations appear more frequently and a new style emerges. This article presents the characteristics of the scriptural quotations appearing in Inferno (1897) and Jacob Wrestles (a fragment following Légendes, written in French and in Swedish in 1898). The linguistic analysis — with includes comparative, discourse, textual and intertextual approaches — is used to define the place and role of scriptural quotations in this literary corpus. This study has revealed three different types of biblical writings which show the spiritual disposition and the religious evolution of the narrator in each text.
Rachilde : Une décadente dans un réseau de bas-bleus
Authors: Finn Michael
Published: June 2019

Il peut paraître surprenant que l’écrivaine décadente Rachilde, connue pour ses provocations et le scandaleux Monsieur Vénus, ait fait partie d’un réseau de bas-bleus formé de femmes à la fois plus vieilles et plus conservatrices qu’elle. La journaliste Camille Delaville défend Rachilde dans la presse et lui ouvre les colonnes de son journal Le Passant, alors que Georges de Peyrebrune, quoiqu’elle critique Rachilde dans son roman à clefs Une décadente, lui sert de confidente pendant plus de vingt ans. Malgré leurs différences, ce qui a joué dans cette relation triangulaire, c’est un certain féminisme qui reconnaît que les relations d’amitié entre femmes sont plus loyales que celles avec les hommes, trop souvent compliquées sinon compromises par la sexualité.AbstractThe decadent writer Rachilde, known for her provocative behaviour and her novel of depravation Monsieur Vénus, was, surprisingly, a member of a network of older, conservative bluestockings. The journalist Camille Delaville defended Rachilde in the press and invited her collaboration in her newspaper Le Passant, while the novelist Georges de Peyrebrune, though critical of Rachilde’s eccentricities in Une décadente (a roman à clefs), served as a maternal confidante for more than 20 years. What linked these three writers was a feminist sense that relations of friendship between women are more loyal that those with men, the latter too often complicated and compromised by sexual questions.
Gaétane de Montreuil, conseillère, bibliothécaire, professeure, critique, éditrice, publicitaire
Authors: Savoie Chantal
Published: June 2019

La trajectoire de la journaliste Gaétane de Montreuil (1867-1951), chroniqueuse à La Presse (1898-1903), romancière, poète, nouvelliste puis directrice du périodique féminin Pour vous mesdames (1913-1915), offre une perspective privilégiée sur l’évolution des stratégies discursives des femmes de lettres suivant les différentes tribunes médiatiques qu’elles occupent.  Au sein d’un champ littéraire canadien-français où la littérature ne se dégage pas encore de l’ensemble de l’espace social et où la critique littéraire est encore embryonnaire, Gaétane de Montreuil agit tour à tour comme conseillère, bibliothécaire, professeure, critique, éditrice et publicitaire. Ce cumul des rôles littéraires féminins, particulièrement denses, marque une étape significative dans l’émergence d’une expertise littéraire au féminin à la fin du XIXe siècle.AbstractAlternately columnist at La Presse (1898-1903), novelist, poet, short story writer, and as the director of women’s magazine Pour vous mesdames (1913-1915), the prolific career of Gaétane de Montreuil (1867-1951) offers a singular perspective on discursive strategies used by women writers, and their evolution according to the literary standpoint, at the turn of the twentieth century. In the context of a literary field still strongly linked to the more general social space, and when literary critique is still embryonic, Gaétane de Montreuil plays different roles: counsellor, librarian, teacher, critique, editor, advertising executive, etc. This plurality is important and significant, particularly in the context of women’s literary practices, at a moment when a feminine literary expertise emerges in the French Canadian context.
Exodes. Les politiques de la littérature d'après «Sortie d'Égypte» de Pierre Michon
Authors: Hamel Jean-François
Published: June 2019

L'Exode est une figure récurrente du discours des écrivains français de la seconde moitié du vingtième siècle qui se sont intéressés aux rapports entre la littérature et la politique. Présente chez Jean-Paul Sartre dès les années 1940, reprise par Roland Barthes dans les années 1950 et 1960, déplacée par Maurice Blanchot au seuil des années 1980, la séquence de la sortie d'Égypte hante aussi certains textes de Pierre Michon et d’Olivier Rolin. Cette figure permet à ces écrivains contemporains d'esquisser les traits caractéristiques d'une génération littéraire née des paradoxes de Mai 68 et de réaffirmer une conception prophétique de la modernité littéraire.AbstractExodus is a recurring figure of speech in many texts of the second half of the twentieth century in France that were concerned with the relationship between literature and politics. Present in Jean-Paul Sartre's writings in the forties, picked up by Roland Barthes in the fifties and sixties, transformed by Maurice Blanchot at the beginning of the eighties, the biblical sequence also haunts some texts by Pierre Michon and Olivier Rolin. This figure allows them to outline the characteristics of a literary generation born of the paradoxes of May 68 and to reaffirm a prophetic conception of literary modernism.
Littérature, spéculation et modernité chez Pascal Quignard
Authors: Roy Nathalie
Published: June 2019

Pascal Quignard, volontiers considéré comme le modèle contemporain du lettré classique, récuse certains des principaux traits de l’esthétique moderne et se réclame, dans la conception de l’art littéraire qu’il développe, de l’Antiquité et de la rhétorique classique. Toutefois, à étudier sa réflexion de plus près, il devient manifeste que sa spéculation littéraire entre fortement en résonance avec la pensée moderne de l’art, et particulièrement avec celle de ses premiers théoriciens, soit les esthéticiens du Cercle d’Iéna. Cet article analyse la pensée esthétique de Quignard à la lumière de cette théorie spéculative qui fonde l’âge moderne, afin d’élucider le rapport complexe qu’entretient l’auteur avec la modernité et de parvenir ainsi à mieux cerner sa pensée.AbstractPascal Quignard, generally considered to be today’s incarnation of the classical man of letters, rejects certain fundamental principles of modern aesthetic thinking while developing a theory of literary art that claims to have its roots in Antiquity and classical rhetoric. However, a closer study of Quignard’s ideas reveals striking parallels between his speculative poetics and modern aesthetic theory, particularly with that developed by modern art’s first theorists, i.e. the members of the Jena Circle. This paper examines Quignard’s theory in light of its similarities with early German Romantic thought, in order to comprehend the author’s complex relationship with Modernity, and thus, to gain better insight into his aesthetic principles.