bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of fenbendazole on fecal microbiome in BPH/5 mice, a model of hypertension and obesity, a brief report
Authors: Beckers Kalie F. , Schulz Christopher J. , Liu Chin-Chi , Barras Elise D. , Childers Gary W. , Stout Rhett W. , Sones Jenny L.
Published: June 2023

Fenbendazole (FBZ) is a common antiparasitic treatment used in research rodent colonies for biosecurity purposes. The effect of this compound has been studied in C57 mice, but never before in a strain of mice that has co-morbidities, such as the blood pressure high (BPH)/5. The BPH/5 mouse is an inbred genetic model of hypertension. While both male and female BPH/5 have high blood pressure, there is a metabolic sexual dimorphism with females displaying key features of obesity. The obese gut microbiome has been linked to hypertension. Therefore, we hypothesized that fenbendazole treatment will alter the gut microbiome in hypertensive mice in a sex dependent manner. To test the influence of FBZ on the BPH/5 gut microbiota, fecal samples were collected pre- and post-treatment from adult BPH/5 mice (males and non-pregnant females). The mice were treated with fenbendazole impregnated feed for five weeks. Post-treatment feces were collected at the end of the treatment period and DNA was extracted, and the V4 region of 16S rRNA was amplified and sequenced using the Illumina MiSeq system. The purpose was to analyze the fecal microbiome before and after FBZ treatment, the results demonstrate changes with treatment in a sex dependent manner. More specifically, differences in community composition were detected in BPH/5 non-pregnant female and males using Bray-Curtis dissimilarity as a measure of beta-diversity (treatment p = 0.002). The ratio of Firmicutes to Bacteroidetes, which has been identified in cases of obesity, was not altered. Yet, Verrucomicrobia was increased in BPH/5 males and females post-treatment and was significantly different by sex (treatment p = 5.85e-05, sex p = 0.0151, and interaction p = 0.045), while Actinobacteria was decreased in the post-treatment mice (treatment p = 0.00017, sex p = 0.5, interaction p = 0.2). These results are indicative of gut dysbiosis compared to pre-treatment controls. Lactobacillus was decreased with FBZ treatment in BPH/5 females only. In conclusion, fenbendazole does alter the gut microbial communities, most notable in the male rather than female BPH/5 mouse. This provides evidence that caution should be taken when providing any gut altering treatments before or during mouse experiments.
Women’s dress and success in the Icelandic banking system
Authors: Árnadóttir Linda Björg , Heijstra Thamar M.
Published: June 2023

In this study on the power of dress in the Icelandic banking sector, we build on Nentwich and colleagues’ (2015) theoretical framework of change agency. We show that the framework bears relevance to changes occurring after the collapse of the Icelandic banking system in 2008. Our aim is to examine the role of dress in the process of change. The data are derived from ten semi-structured interviews with female bank employees, a group that has historically been marginalized within the Icelandic banking sector. Our findings reveal that visible changes in dress have signalled changes in societal norms and attitudes during and after the economic crisis. The disruption has created a window of opportunity for female bank employees to alter dressing norms. This alteration has subsequently increased their agency and visibility, thereby facilitating their upward mobility, mirroring with clients and representing confidence and trustworthiness. We find that changes in dress occur when ideas in society change, and that windows of opportunity are necessary for marginalized groups to expand their agency. Once these windows are created, dress can underline and bolster their agency.
Beyond Afros and activism: Analysis of Black and African American women and fashion, style, dress and identity in fashion studies literature
Authors: Robertson Cydni Meredith , Kopot Caroline , Mestres Jaime L.
Published: June 2023

There is much scholarship on dress and identity and the social, psychological and cultural aspects of dress within the textile and apparel discipline. While there is certainly much literature on dress, identity, fashion and the self, we sought to examine how Black women are centred in this area of research. To achieve our goal, we engaged in a systematic literature review to critically analyse how Black women’s dress and identity are explored in fashion studies scholarship, which involved searching for recurring themes and then making suggestions for future research to fill in gaps regarding Black women’s dress and identity expression. To narrow the scope of this research, we focused on two named theoretical perspectives: Black feminist thought and Africana womanism. After analysis of the publications, we identified two major themes: research centring resistance, oppression and Eurocentric beauty standards and holistic representations of Black women. Overall, our findings highlight that both Black feminist thought and Africana womanism theories could benefit from more expansive utilization within fashion studies research. Both frameworks are lightly referenced, especially Africana womanism, and, because of its rarity, could contribute newer and more critical knowledge to the discipline. There is so much more to explore about Black women’s dress outside of these concepts. We hope to inspire new research on Black women with holistic representations of the self and style.
The journey of a century
Authors: Strada Olga , Olivieri Claudia
Published: June 2023

This article provides an in-depth look at the work Italia-Russia: Un secolo di cinema / Italija-Rossija: Vek kino (‘Italy-Russia: A century of cinema’), edited by the authors and published in Italian and in Russian under the auspices of the Embassy of the Republic of Italy in Moscow (ABCDesign and PBN Print, 2020). For the first time ever, the book delves with singular purpose into the cinematographic relationship between the two countries and much more. The volume is divided into four sections: the first centres on ‘exchanges, crossroads, and joint projects’ from the early 1900s until the new millennium; the second concentrates on the Venice and Moscow film festivals; the third looks at ‘portraits, frames, hidden dreams’ and the final section features the ‘memories and points of view’ of some of the most significant figures in Italian and Russian film.
The Slavic connection in Luchino Visconti’s ‘German trilogy’: Dostoevskian demonism as German apocalypse in The Damned
Authors: Goscilo Helena
Published: June 2023

For decades, critics have viewed Luchino Visconti’s The Damned (1969), the first instalment in his famous German trilogy, simply as a (melo)dramatic depiction of Nazism’s rise, conceived in the director’s characteristic anthropomorphic vein. With Nazism cast as a lethal and sexually perverse phenomenon rooted in the previous generation’s foibles and weaknesses, the film’s hitherto ignored debt to Fyodor Dostoevsky’s novel Demons (1872), however, directs viewers to a more comprehensive insight embedded in the film, namely that history repeats itself, and not obligatorily according to Marx’s famous formulation of the iteration as farce. Indeed, the murderous violence of Russia’s nihilism captured by Dostoevsky expands in Visconti’s film to a national apocalypse that belongs to one of history’s most tragic narratives. Cinematic taxonomy, however, has no category to accommodate Visconti’s original engagement with Dostoevsky’s text, for it falls neither within the established conventions of adaptation nor of intertexts.
In search of beauty: Anticipating the ‘new Renaissance’ of Italian cinema: Interview with Lora Guerra
Authors: Sidorova Svetlana
Published: June 2023

Lora Guerra (Eleonora Yablochkina) was an Italian writer and screenwriter Tonino Guerra’s wife and collaborator. She worked as a translator for a few films produced by her husband with Russian filmmakers, and today she is the curator of Tonino Guerra’s Memorial House in Pennabilli (Rimini). In this interview, she discusses the problems of cinema during the COVID-19 pandemic, the relationship between Italian and Russian cinema, the historical role of Italian cinema and the future of film festivals in Italy. She also reflects on the connection of neorealism with the Italian artistic tradition in literature, theatre and fine arts, on the importance of the ‘word’ as the basis of a screenplay and on the importance of visual and sound images in poetic cinema (both fiction and documentary). Lastly, Lora Guerra reveals details about the production of the documentary Tempo di viaggio (Voyage in Time) filmed in Italy by Andrei Tarkovsky and Tonino Guerra in summer 1979 and released in 1983.
CIAO, 2020! (2020), Russia: Perviy Kanal
Authors: Bonelli Diego
Published: June 2023

Review of: CIAO, 2020! (2020), Russia: Perviy Kanal
Fiamme sul mare (Fire over the Sea), Michał Waszyński (dir.) (1948), Italy: Sirena Film
Authors: Jóźwiak Karol
Published: June 2023

Review of: Fiamme sul mare (Fire over the Sea), Michał Waszyński (dir.) (1948), Italy: Sirena Film
Un enfoque original sobre la génesis y éxito de Coalición Canaria: una contramovilización de élites y la reactivación del viejo pleito insular
Authors: Montesdeoca Pérez Jorge Antonio
Published: June 2023

El artículo propone una revisión de la transición y primeras décadas de existencia de la Comunidad Autónoma de Canarias, centrándose en el rol jugado por los tradicionales grupos de poder de las islas de Tenerife y Gran Canaria, enfrentados acérrimamente por la hegemonía regional desde principios del siglo xix. El análisis constata la posición central que ocuparon estos grupos durante los años que antecedieron y sucedieron el nacimiento de la autonomía, concibiéndose, desde un plano más innovador, el conjunto de acciones políticas desarrollado por tales élites como una contramovilización. Para ello, el artículo identifica y se ocupa de hasta cuatro dinámicas surgidas con la transición que amenazaban con trastocar el statu quo de las islas, analizando, a continuación, algunas de las reacciones desplegadas por las élites en conflicto, alentadas, en gran parte, por el estado de alarma en que se habían posicionado frente a tales dinámicas. En base a esta perspectiva novedosa, la formación política Coalición Canaria se presenta como el producto más importante de la contramovilización a examen, erigiéndose en un instrumento eficaz que ha tenido la capacidad de moldear el orden político del archipiélago, en gran parte, según la voluntad de aquellas élites.
Protagonismos femeninos en Brasil: resistencias y práxis entre los siglos XIX y XXI
Authors: Brito Ximenes Angela Virginia , Lédo Flôres Fernanda , Ribeiro Simon Cavalcanti Vanessa
Published: June 2023

En el mundo contemporáneo y en el tiempo presente, se matizan protagonismos y banderas como expresión del movimiento de mujeres y en agendas específicas. El objetivo de este artículo es realizar un análisis histórico desde las dimensiones política, económica y social de los siglos XIX y XXI en relación a la mujer. Con un abordaje cualitativo, base historiográfica y revisión de la literatura disponible, enfatizamos el aporte teórico dialéctico-histórico, con énfasis en las categorías de resistencia, protagonismo y práxis dentro de la acción y movimiento de mujeres y feministas que proyectaron cambios en el status quo y en las agendas de políticas públicas específicas nacionales. Participar de la vida política y de acciones militantes de mujeres brasileñas describe contextos y procesos intensos de los dos últimos siglos. Especialmente, analizando que, en un primer momento, los vínculos eran más fuertes sobre la cuestión del trabajo, adquiriendo luego un carácter más político y fundamentado.
Sobre las vías de una montaña rusa: narrativa familiar sobre los problemas asociados al consumo de drogas desde una perspectiva situada
Authors: De Oliveira Rodrigues Camila Cristina , Albertín Carbò Maria Pilar , Yasui Silvio , Resende Carvalho Sergio
Published: June 2023

Este artículo pretende comprender cómo se produce la demanda dirigida a la justicia por hospitalización psiquiátrica obligatoria hecha por familias que tienen miembros que hacen un uso problemático de las drogas. Para ello se discute el proceso de investigación realizado con una joven que solicitó este tipo de hospitalización para su madre que, actualmente, es consumidora de crack. Con base en la experimentación e implicación con el campo de estudio, se realizó un trabajo de observación participante y entrevistas con madre e hija. El material fue procesado a partir de la producción de narrativas. Se constató que el discurso de las drogas encubre una fragilidad de los lazos comunitarios modernos, indicando un escenario de inestabilidad en los contextos sociales, culturales y políticos brasileños. En este sentido, las demandas judiciales de hospitalización psiquiátrica, como estrategia para enfrentar el fenómeno de las drogas en la sociedad, revelan la necesidad de revisar la política de drogas y promover un tipo de asistencia más amplio a las personas, especialmente, las que sufren múltiples procesos de exclusión que incluye cuestiones de género y la atención de su red social de proximidad.
First report of mobile colistin resistance gene mcr-1 in avian pathogenic Escherichia coli isolated from turkeys in the Gaza Strip, Palestine
Authors: Thabet Ahmed M. , Alzuheir Ibrahim M. , Al Laham Nahed A. , Helal Belal Y. Abu , Fayyad Adnan F. , Jalboush Nasr H. , Gharaibeh Mohammad H.
Published: June 2023

Background and Aim: Colistin is used to treat avian pathogenic Escherichia coli (APEC), a microorganism that affects turkey meat production in the Gaza Strip and worldwide. However, the recent emergence of plasmid-borne mobile colistin resistance (mcr) genes in pathogenic E. coli strains is a serious antimicrobial resistance (AMR) challenge for both human and animal health. In December 2018, colistin was banned as a veterinary antimicrobial in the Gaza Strip. This study aimed to detect and track the prevalence of colistin-resistant APEC isolated from turkey flocks in the Gaza Strip.

Materials and Methods: This study investigated 239 APEC isolates from turkey flocks in the Gaza Strip between October 2018 and December 2021 (at 6-month intervals). The colistin-resistant APEC strains were detected using the broth microdilution method. The mcr-1 gene was identified using a polymerase chain reaction.

Results: The overall colistin resistance among the isolated APECs was 32.2% during the study period. The average resistance in the first interval was 37.5%, which significantly decreased to 9.3% in the last interval. Among the 77 phenotypically resistant isolates, 32.4% were positive for mcr-1. The average abundance of mcr-1 in the first interval was 66.6%, which decreased to 25% in the last interval.

Conclusion: To the best of our knowledge, this is the first study reporting the presence of the mcr-1 gene among the APEC isolates from turkeys in the Gaza Strip. Banned veterinary use of colistin significantly decreased the percentage of resistant APEC isolates from turkeys in Gaza Strip. Further studies are needed to investigate other colistin resistance genes and track the emergence of AMR.

Keywords: avian pathogenic Escherichia coli, colistin, Gaza Strip, turkey.
An Unusual Cause of Intractable Hiccups
Authors: Butt Edward , Zamora Ernesto , Shabot J. Marc
Published: June 2023

Hiccups are a minor nuisance for most people and usually resolve within minutes. However, for some, they can persist for years and result in severe symptoms and even death. This case report describes a patient found to have a mediastinal lipoma resulting in intractable hiccups. The discussion highlights the pathophysiology, etiologies, and treatments of hiccups.
DEKOLORISASI REMAZOL BLACK B DENGAN PENDEKATAN REDOKS DALAM REAKTOR SKALA GANDA ( SCALE UP REACTOR )
Authors: Rukmana Ayu Fadhilatul , Widodo Didik Setiyo , Djunaidi Muhammad Cholid
Published: June 2023

RBB yang banyak digunakan dalam industri tekstil merupakan salah satu pencemar yang potensial menimbulkan masalah lingkungan. Telah dilakukan penelitian dekolorisasi larutan remazol black B (RBB) dengan metode Fenton termodifikasi Pb. Penelitian ini bertujuan untuk mengetahui kondisi optimum dalam proses dekolorisasi, mengevaluasi tingkat dekolorisasi dalam scale up reactor, dan menentukan karakteristik reaktor dekolorisasi. Pada penelitian ini dilakukan beberapa perlakuan, dalam skala laboratorium menggunakan Pb dari limbah baterai dan H2O2 pada kondisi pH tertentu kemudian ditentukan kondisi optimumnya. Perlakuan kedua, pada pewarna RBB skala ganda ditambahkan reagen Pb, H2O2dan pH optimum. Pengujian penurunan intensitas warna dilakukan dengan spektrofotometer UV-Vis. Hasil penelitian menunjukkan bahwa larutan remazol black B dapat didekolorisasi menggunakan metode Fenton dengan memodifikasi penggunaan ion Fe2+ dengan Pb. Data menunjukkan pH netral optimum pada dekolorisasi zat warna menggunakan 1 g Pb dan H2O2 10%. Persentase dekolorisasi mencapai 93,3% yang menunjukkan potensi metode ini dalam dekolorisasi RBB. Efektivitas dekolorisasi larutan RBB 50 ppm mencapai tertinggi pada kondisi reaktor tertentu dengan spesifikasi ukuran 100 mL H2O2 10%, massa Pb 1 g, waktu dekolorisasi 4 jam (tanpa pengadukan). Proses telah menurunkan nilai COD secarea signifikan dari 4.027,7 mg/L menjadi 65,37 mg/L, atau sebasar 98,37%.
Korosi Besi dengan Elektrolit H2SO4 dan Karakterisasi Produk
Authors: Sianturi Richard Leonardo , Suyati Linda , Astuti Yayuk
Published: June 2023

Telah dilakukan penelitian tentang penentuan laju reaksi korosi pada besi dalam air dan elektrolit asam sulfat. Penelitian ini bertujuan untuk menentukan laju korosi dengan menggunakan metode pengurangan berat, menentukan karakterisitik produk dengan FTIR untuk mengidentifikasi gugus fungsi dari produk, menentukan karakteristik XRD untuk mengetahui struktur lingkup material dari produkdan menentukan kinetika reaksi produk terbaik. Metode yang dilakukan pada penelitian ini terdiri dari 3 tahap, yaitu preparasi larutan H2SO4  0.0675M, 0.125M, 0.25M, 0.5M dan 1M, karakterisasi produk dan uji kinetika reaksi dengan variasi  waktu 0, 15, 30, 45, 60 dan 75 menit. Hasil  penelitian diperoleh  endapan warna coklat dan karakterisasi FTIR Fe2O3 terlihat pada puncak 586 cm-1   Produk hasil reaksi antara besi dengan H2SO4 muncul puncak yang sedikit bergeser pada sudut 2θ 24,10o, 32,90odan 49,55o. Lalu pada hasil reaksi korosi besi dengan H2O muncul puncak sudut 2θ pada 24,36o, 33,24odan 49,43o. Peningkatan kecepatan korosi seiring dengan meningkatnya konsentrasi dari larutan asam sulfat. Konstanta laju order satu dan dua berturut-turut sebesar 1.28 x 10-3 menit-1 dan 2,9  x 10-4 M-1 menit-1.
Pemisahan Logam Timbal Dalam Limbah Cair Simulasi Menggunakan Supported Liquid Membranes (SLM) Berpendukung Dengan Senyawa Pembawa Sinergi D2EHPA
Authors: Djunaidi Muhammad Cholid , Bhakti Danang Kuncoro , Hastuti Rum , Maharani Nesti Dwi
Published: June 2023

Abstrak. Timbal adalah logam yang digunakan secara luas dalam berbagai industri meliputi : batu bara, minyak, peleburan besi/baja, semen, baterai, tekstil, pestisida, gelas dan keramik. Kandungan limbah khususnya timbal sebesar 1,21 mg/L berada dalam berbagai bentuk senyawaan kimia yang berbeda-beda. Pengaruh logam-logam tersebut terhadap organisme akuatik dan manusia sangat berbahaya. Oleh karena itu perlu dilakukan pemisahan logam timbal dari limbah cair dengan metode Supported Liquid Membranes (SLM) berbentuk membrane PTFE dengan campuran pembawa D2EHPA yang memiliki efektivitas dan selektivitas yang tinggi terhadap ion logam Pb. Dalam proses pemisahan/pengadukan digunakan kerosen sebagai pelarut untuk D2EHPA dan asam sebagai larutan fasa penerima digunakan HNO3, HCl, dan H2SO4, terlihat bahwa persen transport timbal fasa umpan ke penerima dengan pengunaan HNO3 relatif lebih tinggi dibandingkan asam fasa penerima lainnya. Sedangkan proses pengadukan melibatkan n-heksan dan kloroform sebagai pelarut organik untuk D2EHPA dan melibatkan juga H2SO4 sebagai larutan fasa penerima. Persen transport fasa umpan ke fasa penerima yang lebih tinggi dicapai pada penggunaan kloroform sebagai pelarut organik.
Radical surgery for non-neoplastic colonic diseases
Authors: Melnyk V. M.
Published: June 2023

Aim. To improve the results of surgical treatment for patients with non-neoplastic colonic diseases by optimizing the choice of radical surgery extent.
Materials and methods. The study material was the analysis of radical surgical interventions performed in 87 patients with non-neoplastic colonic diseases: ulcerative colitis, Crohn’s disease, familial adenomatous polyposis, chronic colonic and coloproctogenic stasis, diverticular colon disease. The age of the operated patients was 20–72 years. There were 49 (56.3 %) men and 38 (43.7 %) women. The criteria for choosing the radical surgery extent for these diseases were defined and substantiated.
Results. There were 3 postoperative mortalities (3.4 %) among patients operated on absolute indications for acute complications of ulcerative colitis and Crohn’s disease. Recurrences of ulcerative colitis, Crohn’s disease and familial adenomatous polyposis occurred in 16 (18.4 %) operated patients in the area of the retained rectal stump and terminal ileum. Malignant transformation of the rectal stump occurred in 5 (5.7 %) patients with these recurrences. The extent of radical surgery in non-neoplastic colonic diseases depended on the diagnosis of the underlying disease, the presence of complications, the depth of wall lesions and the extent of the pathological process, the risk of recurrence in the anatomical parts of the small and large intestine.
Conclusions. Deciding on the extent of the radical stage of surgical intervention depended on the diagnosis, features of the clinical course of non-neoplastic colorectal diseases, recurrences, the general condition of a patient, the pathological process extent and severity. Performing the optimal extent of radical surgery for non-neoplastic colonic diseases helped reduce the number of recurrences in the terminal part of the small intestine to 4 (4.6 %), in the area of the rectal stump to 7 (8.1 %), improved functional outcomes and quality of life in 76 (87.3 %) operated patients.
A case report of achalasia and large epiphrenic diverticulum treated by peroral endoscopic myotomy combined with diverticuloseptotomy
Authors: Kiosov O. M. , Tkachov V. S. , Hulevskyi S. M. , Korobov M. V.
Published: June 2023

The combination of esophageal achalasia with epiphrenic diverticulum is extremely rare and mostly treated surgically. Several cases of successful endoscopic treatment were presented in the literature, but treatment strategy has not yet been defined.
Aim. To present a case of the rare combination as achalasia and giant esophageal epiphrenic diverticulum successfully treated endoscopically.
Case report. We present to your attention a case report of a 75-year-old woman with complete dysphagia, significant weight loss, who was diagnosed with symptomatic epiphrenic diverticulum secondary to achalasia. Upper gastrointestinal endoscopy showed signs of severe fibrosis in the submucosal layer of the diverticulum. She received peroral endoscopic myotomy combined with diverticuloseptotomy made from the same submucosal tunnel. The regression of symptoms from 10 to 2 points according to the Eckardt symptom score clinically showed the treatment success.
Conclusions. The presented endoscopic one-tunnel technique could be an effective miniinvasive option for large symptomatic epiphrenic diverticula associated with achalasia.
Reduction of the risk of failure to achieve blood pressure control in patients with arterial hypertension and coronary heart disease: the role of quercetin
Authors: Solomenchuk T. M. , Prokosa M. I. , Klymkovych O. Yu.
Published: June 2023

Aim. Determine the effect of quercetin on predictors of not reaching target blood pressure (BP) levels in patients with arterial hypertension (AH) and coronary heart disease (CHD).
Materials and methods. 120 patients with stable coronary heart disease and hypertension of the II stage 2–3 degrees (66 women and 54 men) were examined. The patients were divided into 2 groups: Group I – 58 patients who, in addition to basic therapy (ramipril/amlodipine), received quercetin (Corvitin®), Group II – 62 patients who received only basic antihypertensive therapy. The parameters of daily blood pressure monitoring, blood lipid spectrum, C-reactive protein, the concentration of adhesion molecules (s-VCAM, s-ICAM-1), levels of endothelin-1 (ET-1), IL-1, IL-6, TNF-α were determined. Statistical processing of materials was carried out using the following programs: Minitab 21.0, StatPlus Pro 7.6.5, Wizard Pro, Jamovi, MedCalc.
Results. We have established that the risk of not reaching the target level of daily SBP in the group of basic treatment of hypertension (group II) significantly increases with exceeding the level of LDL >4.0 mmol/l (by 3.6 times), an increase in the level of IL-6 >7 ng/ml (by 10 times), an increase in the level of TNF-α >9 pg/ml (by 7 times), an increase in the level of VCAM >1100 ng/ml (by 2.4 times). In the group of people who additionally took quercetin (group I), with an increase in the level of ET-1 >1.1 pg/ml, the risk of failure to reach the target SBP increases by 2.6 times, in the II group – by 3.5 times toward to daily SBP and 8.6 times – toward to daily DBP. We found out that an increase in the concentration of IL-6 > 7 ng/mg significantly increases the risk of arrhythmias by 6 times in group II.
Conclusions. When quercetin is used, it is possible to achieve the target values of SBP (daily, daytime, nighttime) and DBP (daily, daytime, nighttime) in a significantly higher proportion of patients compared with those who are prescribed only standard antihypertensive therapy. Quercetin has an endothelial protective effect, as evidenced by a significant decrease in the levels of vascular endothelial adhesion molecules (s-VCAM), type I intercellular adhesion molecules (s-ICAM-1), ET-1, IL-1, IL-6, TNF-α. The additional use of quercetin against the background of standard antihypertensive therapy significantly reduces the risk of failure to achieve the target levels of SBP, DBP and the risk of heart rhythm disturbances even against the background of increased levels of proinflammatory cytokines and markers of endothelial dysfunction.
Study of the capillary blood flow of the mucous membrane of the peri-implant area by laser Doppler flowmetry
Authors: Maksymov D. Ya. , Varzhapetian S. D. , Parkhomenko D. P. , Salnykov V. I. , Mishchenko O. M.
Published: June 2023

Aim: to conduct a clinical analysis of the capillary blood flow of the mucous membrane of the peri-implant zone using laser Doppler flowmetry (LDF), as well as a comparative assessment of the effectiveness of the implanted structure with a surface, modified with silver nanoparticles (AgNP).
Materials and methods. The study involved 40 patients undergoing rehabilitation for secondary partial adentia by the method of dental implantation. The examinees were divided into 2 groups: Group 1 (20 patients) – gingival formers with a surface modified by plasma electrooxidation and doped with AgNP were installed; Group 2 (20 patients) – standard gingival formers of the used implant system with a polished surface were installed. A control group (20 patients) was formed to determine the reference values. In total, 60 patients were involved in the study. Blood flow velocity in the studied groups was determined by laser Doppler flowmetry.
Results. On the 10th day, when using gingival formers with a surface containing AgNP, a positive trend with increasing the blood flow rate of the mucous membrane of the peri-implant zone (6.97 mm/s) is determined, in contrast of using the gingival formers with a polished surface (5.425 mm/s). In the process of using the gum formers with a surface containing AgNPs, an increase in capillary blood flow rate (by 22.2 %) in a separate location is evidence of a reduction in inflammatory processes and a pronounced anti-inflammatory effect of the AgNP surface.
Conclusions. Higher (by 22.2 %) indicators of capillary blood flow rate of the mucous membrane of the peri-implant zone in patients using gingival formers containing AgNP, compared to polished formers, indicates a pronounced anti-inflammatory effect of the proposed AgNP-doped surface.
The values obtained in the group with AgNPs are as close as possible to the reference indicators of the blood flow rate in the capillary channel of the marginal gingiva of healthy people, which suggests the presence of a pronounced antimicrobial effect of silver nanoparticles on the surface of the gingival formers.
Since blood flow in tissues is directly related to oxygenation of cells, reduction of local acidosis, reduction of inflammatory reactions and determines the state of tissue immunity, as well as directly affects the quality of reparative processes in damaged tissue, the obtained results allow recommending the proposed AgNP – surface for use in clinical practice.
Christopher Kelen & Chengcheng You, Poetics and Ethics of Anthropomorphism: Children, Animals, and Poetry
Authors: Reed Beatrice G.
Published: June 2023

Review/Recension
Helene Ehriander & Corina Löwe (red.), Flickboken och flickors läsning: Flickskapande nu och då
Authors: Cavallin Anna
Published: June 2023

Review/Recension
Instrumented treadmill for run biomechanics analysis: a comparative study
Authors: Bravi Marco , Santacaterina Fabio , Bressi Federica , Morrone Michelangelo , Renzi Andrea , Di Tocco Joshua , Schena Emiliano , Sterzi Silvia , Massaroni Carlo
Published: June 2023

This study aims compare the spatiotemporal and kinematic running parameters obtained by the WalkerView (Tecnobody, Bergamo, Italy) with those recorded by a optoelectronic 3D motion capture system. Seventeen participants were simultaneously recorded by the WalkerView and a motion capture system during running tests on the WalkerView at two different speeds (i.e., 8 km/h and 10 km/h). Per each parameter and speed the Root Mean Square Error (RMSE), the intraclass correlation coefficient (ICC), and the mean of the difference (MOD) and limits of agreement (LOAs) indexes obtained from Bland-Altman analysis were used to compare the two systems. ICCs show an excellent agreement for the mean step time and the cadence at both testing speeds (ICC=0.993 at 8 km/h; ICC=0.998 at 10 km/h); a lower agreement was found for all the kinematic variables. Small differences for some spatio-temporal parameters and greater differences for the kinematic variables were found. Therefore, WalkerView could represent a practical, accessible, and less expensive tool for clinicians, researchers, and sports trainers to assess the characteristics spatio-temporal parameters of running in non-laboratory settings.
Risk management based on the best value approach and its application in conditions of the Czech Republic
Authors: Marvan Petr , Hromádka Vít , Vítková Eva
Published: June 2023

This study focuses on the issue of the best value approach (BVA) method in the public procurement and on the European experience with the implementation of the BVA method, with a focus on the use of this method in the Czech Republic. The key topic here is the effort to manage the risks of the construction project already at the stage of preparation and tender for suppliers of construction works or services, namely, for public contracts evaluated through the BVA. The findings show that public procurement tenderers often misunderstand the concept of project risk as managerial, temporal, economic, or qualitative risk. Case studies show reserves and possibilities for improvement. The goal of the study is to provide a framework for understanding and explaining the principles and methods of evaluating a qualitative criterion in the form of the risk assessment plan.
Analysis of mango fruit surface temperature using thermal imaging and deep learning
Authors: Pugazhendi Pathmanaban , Balakrishnan Kannaiyan Gnanavel , Anandan Shanmuga Sundaram , Somasundaram Chermadurai
Published: June 2023

Thermal imaging has the potential to measure the object’s surface temperature. This study investigated the thermal behavior of mango fruit stored in a refrigerated environment. Thermal images of the fruit were collected with sufficient quality by supplying hot air to the acquisition environment. Grey-Level Co-occurrence Matrix (GLCM) features of mango images were determined to distinguish the subtle and noticeable changes. The thermal images were analyzed to find the temperature difference between the different regions of the fruit. The temperature of the bruise boundary (T

bd
) was higher than the bruised center (T

C
) throughout the storage period. In addition, an enhanced deep-learning model was used to predict the damaged mango. Over 10 days, 3500 thermal images were obtained from the 400 mangoes. In that, 80 % of the images were used for training, 10 % for testing, and 10 % for validation. The model achieved a classification accuracy of 99.6 %.
Extraction of uranium and rare earths from mineralized ferruginous sandstone, southwestern Sinai
Authors: El Hady Saleh Mohamed
Published: June 2023

A technological sample assaying 943 ppm U and about 0.97 % RE2O3 in a mineralized ferruginous sandstone has been collected from Wadi Sedri area of southwestern Sinai. The XRD analysis has releaved the presence of uranium minerals namely; coffinite and sodium meta-autonite but the rare earths adsorbed on the clay minerals inter the ore sample. Leaching of uranium and rare earths from the studied sample is based on ferric sulfate salt. The relevant conditions e.g. (6 g/L ferric sulfate concentration, 1/5 S/L ratio, time 8 h, T = 80 °C and 7.5 g/L H2SO4 concentration) of the ferric ion leaching for uranium and rare earths have been optimized. From the obtained leach liquor, the rare earths are precipitated as oxalates. This is followed by uranium recovery using anion exchange resin as impregnated Lewatite Monoplus M 500/Alamine 304. Therefore, highly pure products of uranium and rare earths have been obtained and chemically analyzed.
Mechanical property improvement of oil palm empty fruit bunch composites by hybridization using ramie fibers on epoxy–CNT matrices
Authors: Wulan Praswasti Pembangun Dyah Kencana , Yolanda Yogi
Published: June 2023

Oil palm empty fruit bunches (OPEFBs) can be transformed into composite boards with higher selling value when their cellulose is used as a fiber. Manufacturing composites with hybridization techniques can improve their properties. This study combined OPEFBs and ramie fibers in an epoxy–carbon nanotube (CNT) matrix. The proportion of OPEFBs and ramie fibers was varied (3:7, 5:5, and 7:3), with a total fiber content of 10% by volume and a matrix of 90% by volume. Alkali treatment using NaOH solution was applied to the fiber to remove impurities from the surface. CNTs were functionalized using nitric acid followed by hydrogen peroxide to improve compatibility. Surface treatment was conducted on fibers and CNTs to increase the bonds between these components in the composite material. The hybridization of OPEFBs/ramie fibers improved the tensile strength in the 3:7TR, 5:5TR, and 7:3TR composites by 127, 37, and 12%, respectively, compared to the 10T composite. The flexural strength of the 5:5TR hybrid composite increased by 120%, and that of the 3:7TR and 7:3TR composites increased by 83% against the 10R composite. The 3:7TR hybrid composite showed the best mechanical properties.
Effects of conditioned pain modulation on Capsaicin-induced spreading muscle hyperalgesia in humans
Authors: Schliessbach Jürg , Siegenthaler Andreas , Graven-Nielsen Thomas , Arendt-Nielsen Lars , Curatolo Michele
Published: June 2023

Objectives

Muscle pain can be associated with hyperalgesia that may spread outside the area of primary injury due to both peripheral and central sensitization. However, the influence of endogenous pain inhibition is yet unknown. This study investigated how endogenous pain inhibition might influence spreading hyperalgesia in experimental muscle pain.

Methods

Conditioned pain modulation (CPM) was assessed in 30 male volunteers by cold pressor test at the non-dominant hand as conditioning and pressure pain thresholds (PPT) at the dominant 2nd toe as test stimuli. Subjects were classified as having inhibitory or facilitating CPM based on published reference values. Subsequently, muscle pain and hyperalgesia were induced by capsaicin injection into the non-dominant supraspinatus muscle. Before and 5, 10, 15, 20, 30, 40, 50 and 60 min later, PPTs were recorded at the supraspinatus, infraspinatus and deltoid muscle, ring finger and toe.

Results

Compared to baseline, PPTs decreased at the supraspinatus, infraspinatus and deltoid muscle (p≤0.03), and increased at the finger and toe (p<0.001). In facilitating CPM (n=10), hyperalgesia occurred at 5, 10, 15, 20 and 40 min (p≤0.026). In inhibitory CPM (n=20), hyperalgesia only occurred after 10 and 15 min (p≤0.03). At the infraspinatus muscle, groups differed after 5 and 40 min (p≤0.008).

Conclusions

The results suggest that facilitating CPM is associated with more spreading hyperalgesia than inhibitory CPM. This implies that poor endogenous pain modulation may predispose to muscle pain and spreading hyperalgesia after injury, and suggest that strategies to enhance endogenous pain modulation may provide clinical benefits.
Logging Residue Assessment in Salvage Logging Areas
Authors: Udali Alberto , Garollo Lorenzo , Lingua Emanuele , Cavalli Raffaele , Grigolato Stefano
Published: June 2023

Salvage logging operations often occur after large disturbances and usually leave behind a substantial quantity of residues, which is fundamental for maintaining soil fertility and facilitating ecosystem dynamics. This study aims to estimate the amount of logging residues following salvage operations categorized by two wood harvesting systems: Cut-To-Length (CTL) and Full-Tree System (FT). Logging residues in the harvested areas were sampled using linear transects and the data collected were divided into classes based on diameter. The quantity of residues was estimated using the Brown method for Fine Wood Debris (FWD) and the Van Wagner method for Coarse Wood Debris (CWD). Furthermore, the carbon and nutrient content associated with logging residues were also determined, considering their interaction with the soil organic layer. Overall, a higher quantity of FWD was detected in the sites cleared with the FT system and a higher quantity of CWD in the sites logged with the CTL system. Differences could be observed for all three years and systems considered, but only the third year reported statistically significant results (p<0.01). The soil and residue chemical analysis for carbon and nutrient contents revealed a high amount of carbon stored in a potential layer of 10 cm of soil (up to 85 Mg·C·ha-1), while only up to 15 Mg·C·ha-1 for the woody material.
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity
Authors: Christova Tania , Ho Stephanie KY , Liu Ying , Gill Mandeep , Attisano Liliana
Published: June 2023

The establishment of axon‐dendrite polarity is fundamental for radial migration of neurons, cortical patterning, and formation of neuronal circuits. Here, we show that the receptor tyrosine kinases, Ltk and Alk, are required for proper neuronal polarization. In isolated primary mouse embryonic neurons, the loss of Ltk and/or Alk causes a multiple axon phenotype. In mouse embryos and newborn pups, the absence of Ltk and Alk delays neuronal migration and subsequent cortical patterning. In adult cortices, neurons with aberrant neuronal projections are evident and axon tracts in the corpus callosum are disrupted. Mechanistically, we show that the loss of Alk and Ltk increases the cell‐surface expression and activity of the insulin‐like growth factor 1 receptor (Igf‐1r), which activates downstream PI3 kinase signaling to drive the excess axon phenotype. Our data reveal Ltk and Alk as new regulators of neuronal polarity and migration whose disruption results in behavioral abnormalities.
Ülkemizde 2018 – 2022 Yılları Arasında Müze Eğitimi ile ilgili Yapılan Tezlerin İncelenmesi
Authors: MERTOĞLU Hatice , GÜRBEY USTA Zübeyde Burçin
Published: June 2023

Günümüzde dünyanın her alanında yaşanan gelişmeler doğrultusunda müzeler önem kazanmıştır. Müzede eğitim vizyonlaşmış, geleneksel müze anlayışı değişime uğramıştır. Bu araştırmada ülkemizde 2018 – 2022 yılları arasında müze eğitimi ile ilgili yapılan tezlerin çeşitli kriterlere göre incelenmesi amaçlanmıştır. Bu çalışmanın yöntemi nitel araştırma yöntemlerinden biri olan doküman analizi olarak belirlenmiştir. Tezler, YÖK Ulusal Tez Merkezi’ne kayıtlı olan 2018-2022 yılları içerisinde yazılmış 20 lisansüstü “müze eğitimi” tezlerinden oluşmaktadır. Ülkemizde yapılan müze eğitimi ile ilgili tezler çeşitli kriterler açısından incelenmiştir. Yapılan bu çalışmada verilerin analizi betimsel olarak yapılmıştır. Araştırmanın sonuçlarına göre, lisansüstü tezlerin büyük bir kısmının Ankara Üniversitesi’nde yer aldığı, Eğitim bilimleri enstitüsü bünyesinde ve disiplin alanının ise Disiplinlerarası Müze Eğitimi olduğu saptanmıştır. Tezlerde genelde “çevrimiçi müze eğitimi tasarımı” konusu, nitel araştırma yönteminin ve betimsel tarama deseninin kullanıldığı, ortaokul öğrencilerinin çalışma grubu seçildiği, yarı yapılandırılmış görüşme formunun veri toplama aracı olarak kullanıldığı ve veri analiz yöntemi olarak içerik analizinin kullanıldığı tespit edilmiştir. Bilindiği üzere 2018’de öğretmen yetiştirme alanındaki çağdaş gelişmelere paralel olarak Öğretmen Yetiştirme Lisans Programları yenilenmiştir. Bu yeniliklerden birisi de “Müze eğitimi” dersinin Eğitim fakültesi lisans programlarında tüm branşlarda Meslek Bilgisi Seçmeli Dersler grubunda yer almasıdır. Ayrıca Fen bilgisi öğretmenliği lisans programında da “okul dışı öğrenme ortamları” dersi zorunlu ders olarak yer almaktadır. Buna rağmen müze eğitimi ile ilgili tezlerin sınırlı sayıda olması dikkat çekicidir. Bu bağlamda, yenilenen eğitim programlarında yer alan müze eğitimi derslerinin ve MEB’in son yıllarda okul dışı eğitime verdiği öneme binaen, müze eğitimi ile ilgili daha fazla lisansüstü tezlerinin yazılması, araştırmaların yapılması önerilebilir.
Transformaciones urbanísticas en «Astigi» (Écija) a partir del siglo III d. C.: ¿decadencia o adaptación?
Authors: Atenciano-Crespillo Jesús
Published: June 2023

El tránsito a la nueva realidad tardoantigua se reflejó materialmente en diversas transformaciones en los elementos urbanísticos: desde las murallas hasta el callejero, pasando por los espacios domésticos y las necrópolis. En el presente documento se ofrece un mapa que localiza estas mutaciones urbanas en distintas zonas de la ciudad de Écija (Sevilla) que no se encuentran estudiadas en profundidad. Este se acompaña de un análisis general del fenómeno urbano tardoantiguo para, posteriormente, culminar con la interpretación y el parangón de ambos apartados.
Visiting a Sufi Shaykh: A Contemporary Experience of Religious Pilgrimage
Authors: Maltabarova Makhabbad
Published: June 2023

Modern experience of spiritual search has mixed up all the colors of the religious domain. It is no longer a strict definition of what the term pilgrimage implies. There is a growing number of seemingly secular places visited by both members of traditional religious institutions and New Age movements. However, the Western culture of pilgrimage is still recognized as individual and not accepting religious elements as such. Using reliable sociological approaches and the ethnographical material, the present article challenges this assumption and seeks to create a more productive discussion on the topic. For this, it examines the Naqshbandi Haqqani Sufi community of Lefke (Cyprus), a place of pilgrimage for Muslims, non-Muslims, Europeans, Americans—all motivated by the goal of visiting a Sufi shaykh. The article analyzes the pilgrimage to Lefke by means of John Urry’s three bases of co-presence and illustrates how the Islamic vocabulary of pilgrimage has also changed in adaptation to the new realities of the post-secular world. As a result, it is argued that Sufism, with its historically proven ability to combine the individual and collective spheres of religious life, can provide a useful framework for understanding the contemporary pilgrimage phenomenon.
Environmental Activism in Indonesian Pesantren: The Role of Lora in Mainstreaming Islamic Eco-theology in Tapal Kuda, East Java
Authors: Hasan Nor , Mardhatillah Masyithah , Abadi Moh. Mashur , Hidayat Ainur Rahman
Published: June 2023

Young kiais (also known as lora in Madura culture) at Tapal Kuda, East Java have become increasingly involved in environmental issues, yet not in a fully coordinated or organized manner. This article attempts to give a brief portrayal of this fledgling movement and its moderate form of religious environmentalism. This study seeks to identify the factors responsible for this new environmentalist movement, the individuals behind it, and its impact in East Java. Through interviews and observations it is argued that the lora show moderation in propagating their concerns and empowering the community to take care of the environment as a manifestation of their Islamic eco-theological ethics. The informants responded to internal and external factors described in terms of their typology; participant, proponent, and activator. The movement has a measurable impact in terms of awareness, community establishment, cooperation with relevant institutions and supporting facilities and shows significant potential to develop further and establish itself in the region, while overcoming several challenges that slow its activism. The results of this study are expected to highlight the contributions of what so-called the Islamic eco-theology in Indonesian pesantren that participate in the current efforts to protect and preserve the natural environment.
Muslim Intellectuals’ Insights and Their Contributions to the Development of Alternative Social Science in the Malay-Indonesian Context
Authors: Bachtiar Hasnan , Baidhawy Zakiyuddin
Published: June 2023

This article aims to examine the interaction between social science and tradition in Malay-Indonesian scholarship, with a particular focus on the perspectives of Muslim intellectuals. This interaction is represented by two approaches: autonomous social science and prophetic social science. The article argues that both approaches have their distinct inclinations in perceiving and formulating theoretical foundations. These inclinations are shaped by their unique qualities, alternative values, intellectual stances, and thinking styles. Moreover, during the process of development, they are influenced by various factors that give them their distinct characteristics, such as autonomy, a problem-based approach, and a strong commitment to rethinking society and driving change and transformation. The social concept of Islam Nusantara represents this development. It is a collection of arguments and practices of Islam adopted by Muslims in Nusantara, which have shaped patterns of social relations and cohesiveness through communicative actions throughout a specific historical epoch in the region. The article also highlights two essential factors that significantly shape these approaches: the dominant schools of thought in social science and the peculiar Malay-Indonesian traditions. While Western social sciences have played a central role in understanding certain concepts, Malay-Indonesian traditions have contributed significantly to shaping the paradigm of local scholars.