bluuebunny/crossref_metadata_2025 huggingface dataset:
An Exploratory Study on the Motivations behind Visiting the Holocaust Museum of Porto
Authors: Magano José , Fraiz-Brea Jose A. , Leite Ângela
Published: December 2022

This study aims to identify the reasons why people visit the Holocaust Museum of Porto (HMP) and if other variables (sociodemographic ones, visitors’ similarity with Jewish community members, their knowledge of dark tourism, and experience with other Holocaust-related destinations) also influence such motivators. A quantitative analytical, observational and case-control study was conducted based on a survey of 488 respondents who completed a self-administered questionnaire at the HMP. Statistical data analysis included descriptive statistics, an exploratory factor analysis, a confirmatory factor analysis, convergent validity (through composite reliability and average variance extracted), and discriminant validity (through square roots of the AVE values). The findings reveal that visitors are drawn by factors such as novelty and knowledge-seeking and that the motives for visiting the museum differ according to their sociodemographic characteristics, visitors’ similarity with members of the Jewish community, and their knowledge of dark tourism and experience with other Holocaust-related destinations. Sociodemographic variables, previous practices related to the Holocaust and similarity have an impact on the drivers behind visiting dark places. These results contribute to dark tourism literature with an improved understanding of tourist behavior toward Holocaust memorial museums. In addition to filling a gap, it provides a comprehensive insight into the specific motivators behind visiting the HMP, possibly allowing this museum to better design tourist experiences, thus increasing the potential to attract more visitors and keep alive the memory of such atrocities that cannot be repeated.
Turning Crisis into a Sustainable Opportunity Regarding Demand for Training and New Skills in Labor Market: An Empirical Analysis of COVID-19 Pandemic and Skills Upgradation
Authors: Hayat Muhammad Azmat , Chaudhry Mumtaz Anwar , Batool Maryam , Ghulam Huma , Khan Abid Raza , Spulbar Cristi , Zahid Naeem Muhammad , Birau Ramona , Criveanu Maria Magdalena
Published: December 2022

The COVID-19 pandemic has brought rampant changes in skill needed in the labor market. It has accentuated technological disruption leaving millions in dire need of reskilling and upskilling. In this paper, we empirically analyze the impact of the COVID-19 pandemic related lockdown on the thrust of skills upgradation among people. By analyzing the Google trends data of 13 countries, we test the effect of the lockdown implementations on the urge to upgrade the skills through online searches for skills enhancement. Using difference-in-difference estimation approach, we found a substantial hike in the frequency of search terms related to skills upgradation. Our results suggest that people are utilizing the excess time, made available due to lockdowns, by exploring avenues to enhance their skills to accumulate human capital. The online educational platforms have been proven vital. The findings of this study establish the causal link between use of online education platforms and human capital development.
A Theoretical Framework for Analyzing Student Achievement in Software Education
Authors: Mun Changbae , Ha Hyodong
Published: December 2022

Software education and its value are strongly emphasized among basic university courses in the era of the fourth industrial revolution. Numerous university students use the internet and various software in their daily lives. However, there is a lack of awareness on the necessity and value of software education. Therefore, a systematic software education methodology for university students is required. Moreover, an educational strategy that meets the needs of students is required to provide students with more efficient software education. This study aims to analyze the intention of using software among students and build a classification scheme for educational intentions to achieve educational objectives by establishing a strategy for software education. Therefore, this study presents a strategic framework for which a 2 × 2 matrix is proposed based on hedonic motivation and effort expectancy. We examine various aspects of its practical application, and derive improvements through focus group interviews. An empirical experiment was carried out in a basic Python programming class in order to find variables in the framework. The framework was verified in terms of three aspects: utility, convenience, and elasticity. The software education strategy framework developed in this study will help achieve educational goals and resolve efficiency issues in the software education field in the future.
Charging Stations Selection Using a Graph Convolutional Network from Geographic Grid
Authors: Qin Jianxin , Qiu Jing , Chen Yating , Wu Tao , Xiang Longgang
Published: December 2022

Electric vehicles (EVs) have attracted considerable attention because of their clean and high-energy efficiency. Reasonably planning a charging station network has become a vital issue for the popularization of EVs. Current research on optimizing charging station networks focuses on the role of stations in a local scope. However, spatial features between charging stations are not considered. This paper proposes a charging station selection method based on the graph convolutional network (GCN) and establishes a charging station selection method considering traffic information and investment cost. The method uses the GCN to extract charging stations. The charging demand of each candidate station is calculated through the traffic flow information to optimize the location of charging stations. Finally, the cost of the charging station network is evaluated. A case study on charging station selection shows that the method can solve the EV charging station location problem.
Soil Anti-Scourabilities of Four Typical Herbaceous Plants and Their Responses to Soil Properties, Root Traits and Slope Position in Northeast China
Authors: Wang Xueshan , Guo Mingming , Liu Jielin , Kong Xiaolei , Peng Daqing , Zhang Qiang
Published: December 2022

Vegetation has been proven to be an effective measure to mitigate soil erosion in most regions and climates. However, it is not clear how some herbaceous plants affect the ability of soil to resist slope flow erosion in the Mollisol region of Northeast China. In this study, four herbaceous plant plots of 50 m × 4.5 m, including Zea mays L., Sorghum bicolor × Sudanense, Avena sativa L. and Lolium multiflorum Lam., were established in a sloping land with an abandoned land as the control to detect the effect of herbaceous plants on soil anti-scourability (ANS). A hydraulic flume experiment was carried out to determine the soil ANS, and the root traits and soil properties were also measured at different slope positions. The results showed that the mean soil ANS ranged from 17.55 to 94.77 L g−1 among different herbaceous plants, of which the Lolium multiflorum Lam. showed the strongest controlling effect on soil ANS (259.87%), followed by Sorghum bicolor × Sudanense (66.87%) and Avena sativa L. (18.12%), while the soil ANS of Zea mays L. decreased by 33.37% compared with the control. Soil ANS varied with slope position, and the mean soil ANS at the upslope was 116.50–134.21% higher than that of the middle slope and downslope. Additionally, soil ANS was positively related to root mass density (RMD), root length density (RLD), root surface area density (RSAD), soil total porosity and field capacity but was negatively related to soil bulk density (p < 0.05). Furthermore, the Lolium multiflorum Lam. exhibited better root distribution (i.e., high RSAD, RLD, RMD, and low root diameter) and soil physical structure (i.e., high soil porosity structure, water-holding capacity and low bulk density) than other plant species. Thus, the Lolium multiflorum Lam. is beneficial for enhancing soil erosion resistance to overland flow, especially at the up and middle slopes, and it could be preferred to control sloped soil erosion in Northeast China.
Recent Developments in Thermoelectric Generation: A Review
Authors: Sanin-Villa Daniel
Published: December 2022

The world’s growing energy demand poses several concerns regarding the rational and efficient use of energy resources. This is also the case for many industrial processes, where energy losses and particularly thermal losses are common. Thermoelectric generators offer an alternative to address some of these challenges by recovering wasted heat and thereby increasing the overall efficiency of these processes. However, the successful operation of the thermoelectrical modules meant to carry this process is only possible when pairing these to an external control system; such a system plays an important role in predicting and operating such modules at its maximum power point. In this review paper, recent developments in the field of thermoelectric technology are discussed along with their mathematical models, applications, materials, and auxiliary devices to harvest thermal energy. Moreover, new advancements in phenomenological models are also discussed and summarized. The compiled evidence shows that the thermal dependence properties on the thermoelectric generator material’s modules and the mismatching thermal conditions play an important role in predicting power output in those systems, which prove the importance of including those parameters to enhance the accuracy of the energy production prediction. In addition, based on the evaluation of the mathematical models, it is shown that more studies are required to fill the gap between the current state-of-the-art of the technology and adjacent modeling techniques for the design and evaluation of thermal energy harvesting systems employing thermoelectric arrays under mismatching thermal conditions.
Skin Brightening Efficacy of Grammatophyllum speciosum: A Prospective, Split-Face, Randomized Placebo-Controlled Study
Authors: Chowjarean Verisa , Phiboonchaiyanan Preeyaporn Plaimee , Harikarnpakdee Saraporn
Published: December 2022

Grammatophyllum speciosum Blume is widely used as a traditional herbal medicine throughout Asia. The purpose of the study was to investigate the clinical skin-whitening effect and in vitro evaluation of the underlying mechanism of G. speciosum pseudobulb ethanolic extract (GSE). The study examined the inhibitory effects of GSE on B16F10 tyrosinase activity, melanin content, and mushroom tyrosinase. The GSE was developed into a hydrogel formulation and evaluated for its stability. A randomized, double-blind, placebo-controlled study of hydrogel containing GSE was conducted on healthy volunteers to examine the skin irritation and skin-whitening effect using Maxameter® MX 18 and Visioface® RD. GSE significantly inhibited the formation of melanin in B16F10 cells without affecting the tyrosinase enzyme and mushroom tyrosinase. After 6 months, the hydrogel containing a 0.5% (w/w) GSE formulation showed good physicochemical stability. There was no skin irritation caused by GSE hydrogel in participants. GSE hydrogel significantly increased melanin reduction activity by 8.285% after 56 days of treatment, whereas the hydrogel base was −0.949%. The results revealed that G. speciosum decreased melanogenesis in B16F10 cells and increased melanin-reduction activity in our clinical study. Hence, G. speciosum could be used in skincare products as a form of dermatological-whitening agent.
The Circular Economy of Steel Roofing and Cladding and Its Environmental Impacts—A Case Study for New Zealand
Authors: Roy Krishanu , Dani Aflah Alamsah , Say Vince , Fang Zhiyuan , Lim James B. P.
Published: December 2022

This paper investigates the environmental impacts of two commonly used steel roofing and wall-cladding products in New Zealand over their life cycle, taking into consideration the recycling process. The recycling process of steel is in line with the Circular Economy (CE) approach, where the goal is to prolong the material’s lifetime and possibly reduce its environmental impacts and material waste. Although the benefit of recycling steel is well recognised, the environmental impact values of different specific steel products cannot be generalised and need to be estimated. For this, life cycle assessment (LCA) methodology and Environmental Product Declaration (EPD) were implemented to quantify the environmental impacts of the investigated steel products and to analyse the significance of the recycling process in reducing the impacts on the environment. This study considered modules C1–C4 and D to estimate the impacts of steel products. It was found that the recycled steel materials have an effect on reducing the environmental impacts, particularly the global warming potential (GWP) and photochemical ozone creation potential (POCP), both of which were negative and of −2.36 × 106 kg CO2eq and −8.10 × 102 kg C2H4eq, respectively. However, it is important to note that not all impacts were reduced by recycling steel, which creates trade-offs within each impact indicator. In addition, when compared with locally sourced material cladding, the imported material cladding had a 6% higher negative impact value for both GWP and POCP.
Evaluation of Alternative Fuels for Coastal Ferries
Authors: Laasma Andres , Otsason Riina , Tapaninen Ulla , Hilmola Olli-Pekka
Published: December 2022

The International Maritime Organization (IMO) and European Union (EU) have set targets to reduce greenhouse gas (GHG) emissions. Focusing on ships above 5000 GT, their measures exclude several ship types, such as fishing vessels, offshore ships, and yachts. However, smaller ships generate 15–20% of the total GHG emissions. Multiple potential fuel alternatives are already in use or have been investigated to minimize carbon emissions for coastal ferries. This study evaluates the possibility of using alternative fuels for small ferries by seven different parameters: technical readiness, presence of regulations, GHG emission reduction effectiveness (with two different criteria), capital expenditure (Capex), operating expenditure (Opex), and ice navigation ability. The assessment is based on an evaluation of state-of-the-art literature as well as second-hand statistics and press releases. The study also reports the most recent implementations in each alternative technology area. As a result, it was found that although there are several measures with high potential for the future, the most feasible fuel alternatives for coastal ferries would be fully electric or diesel-electric hybrid solutions.
Review on the Reconstruction of Transition Dipole Moments by Solid Harmonic Spectrum
Authors: Qiao Yue , Chen Jiaqi , Chen Jigen
Published: December 2022

In the process of intense laser–matter interactions, the transition dipole moment is a basic physical quantity at the core, which is directly related to the internal structure of the solid and dominates the optical properties of the solid in the intense laser field. Therefore, the reconstruction of the transition dipole moment between solid energy bands is extremely important for clarifying the ultrafast dynamics of carriers in the strong and ultrashort laser pulse. In this review, we introduce recent works of reconstructing transition dipole moment in a solid, and the advantages and drawbacks of different works are discussed.
Matching Supply and Demand with Lead-Time Dependent Price and with Safety Stocks in a Make-to-Order Production System
Authors: Das Sonu Kumar , Kuthambalayan Thyagaraj S.
Published: December 2022

We studied the ability to reduce the supply–demand mismatch of a periodic Make-to-Order (MTO) production system using safety stocks with marketing managing demand using lead-time guarantee and price as levers. The aim is to understand the interdependencies between lead-time guarantee, price, and safety stocks. We modeled the problem as an unconstrained stochastic non-linear programming problem, maximizing the expected profit per-unit time and obtaining a closed-form solution. The price is a function of the lead-time guarantee. Based on the sensitivity analysis of problem parameters, we found that lead-time competitiveness is adversely affected by a low safety stock level, MTO production rate (i.e., low supply capability), and product price (i.e., high demand volume). A shorter lead-time requires higher safety stock through reduced product and inventory holding costs. A higher price for a shorter lead-time in a lead-time-sensitive market reduces the safety stock. In a price-sensitive market, lead-time is decreased instead of the price. Demand variation results in longer lead-time and higher safety stock (provided the holding cost is low). For a higher price premium, price increases and lead-time decrease (safety stock increases). The integrated operation-marketing model captures the complex trade-offs not seen in a hierarchical model to produce better solutions.
COVID-19 Associated Myocarditis Clinical Outcomes among Hospitalized Patients in the United States: A Propensity Matched Analysis of National Inpatient Sample
Authors: Davis Monique G. , Bobba Aniesh , Chourasia Prabal , Gangu Karthik , Shuja Hina , Dandachi Dima , Farooq Asif , Avula Sindhu Reddy , Shekhar Rahul , Sheikh Abu Baker
Published: December 2022

Coronavirus-19 (COVID-19), preliminarily a respiratory virus, can affect multiple organs, including the heart. Myocarditis is a well-known complication among COVID-19 infections, with limited large-scale studies evaluating outcomes associated with COVID-19-related Myocarditis. We used the National Inpatient Sample (NIS) database to compare COVID-19 patients with and without Myocarditis. A total of 1,659,040 patients were included in the study: COVID-19 with Myocarditis (n = 6,455, 0.4%) and COVID-19 without Myocarditis (n = 1,652,585, 99.6%). The primary outcome was in-hospital mortality. Secondary outcomes included mechanical ventilation, vasopressor use, sudden cardiac arrest, cardiogenic shock, acute kidney injury requiring hemodialysis, length of stay, health care utilization costs, and disposition. We conducted a secondary analysis with propensity matching to confirm results obtained by traditional multivariate analysis. COVID-19 patients with Myocarditis had significantly higher in-hospital mortality compared to COVID-19 patients without Myocarditis (30.5% vs. 13.1%, adjusted OR: 3 [95% CI 2.1–4.2], p < 0.001). This cohort also had significantly increased cardiogenic shock, acute kidney injury requiring hemodialysis, sudden cardiac death, required more mechanical ventilation and vasopressor support and higher hospitalization cost. Vaccination and more research for treatment strategies will be critical for reducing worse outcomes in patients with COVID-19-related Myocarditis.
Improved Expression of SARS-CoV-2 Spike RBD Using the Insect Cell-Baculovirus System
Authors: Poodts Joaquín , Smith Ignacio , Birenbaum Joaquín Manuel , Rodriguez María Sol , Montero Luciano , Wolman Federico Javier , Marfía Juan Ignacio , Valdez Silvina Noemí , Alonso Leonardo Gabriel , Targovnik Alexandra Marisa , Miranda María Victoria
Published: December 2022

Insect cell-baculovirus expression vector system is one of the most established platforms to produce biological products, and it plays a fundamental role in the context of COVID-19 emergency, providing recombinant proteins for treatment, diagnosis, and prevention. SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain (RBD) with the host’s cellular receptor. As RBD is required for many applications, in the context of pandemic it is important to meet the challenge of producing a high amount of recombinant RBD (rRBD). For this reason, in the present study, we developed a process based on Sf9 insect cells to improve rRBD yield. rRBD was recovered from the supernatant of infected cells and easily purified by metal ion affinity chromatography, with a yield of 82% and purity higher than 95%. Expressed under a novel chimeric promoter (polh-pSeL), the yield of rRBD after purification was 21.1 ± 3.7 mg/L, which is the highest performance described in Sf9 cell lines. Finally, rRBD was successfully used in an assay to detect specific antibodies in COVID-19 serum samples. The efficient strategy herein described has the potential to produce high-quality rRBD in Sf9 cell line for diagnostic purpose.
Heterologous Booster Dose with CORBEVAX following Primary Vaccination with COVISHIELD Enhances Protection against SARS-CoV-2
Authors: Jaggaiahgari Shashidhar , Munigela Apoorva , Mitnala Sasikala , Gujjarlapudi Deepika , Simhadri Venu , D Nageshwar Reddy
Published: December 2022

Despite effective vaccination programs, waning immunity in the vaccinated populations and the emergence of variants of concern posed a risk of breakthrough infections. A booster dose was demonstrated to provide substantially increased protection against symptomatic disease and hospitalization. We aimed to evaluate immune memory and the efficacy of reducing the rate of SARS-CoV-2 infection post heterologous booster with CORBEVAX after primary vaccination with two doses of COVISHIELD. SARS-CoV-2 S1/S2 spike IgG and RBD-specific antibody responses were elicited with both booster vaccines, with a greater response in individuals receiving heterologous booster. T and B memory responses were increased with booster dose, whereas B memory needed a longer duration to develop in individuals who received a homologous booster (90 days) in comparison to a heterologous booster (30 days). RBD-specific B memory and antibody-secreting (non-memory) B lymphocytes were enhanced with both boosters; however, the duration of response was longer with the heterologous booster compared to the homologous, indicating greater protection with the heterologous booster. The rate of infection 14 days after administration of the heterologous booster was comparatively lower than that of the homologous booster, with the symptoms being much less or asymptomatic.
Uptake of Microplastics in the Wedge Clam Donax trunculus: First Evidence from the Mediterranean Sea
Authors: Olivieri Zoe , Cesarini Giulia , Orsini Monica , De Santis Serena , Scalici Massimiliano
Published: December 2022

The Mediterranean Sea is affected by microplastic contamination, and several methods have been developed to investigate the degree of environmental plastic pollution. Among these, the use of bioindicators is strongly suggested, and in particular bivalves are sensitive sentinel organisms of the level of microplastic contamination. The wedge clams Donax trunculus is an important edible species for the Mediterranean, area but only rudimentary knowledge is available about microplastic contamination in this species, and no data are available about this topic in the Mediterranean Sea. Therefore, the main aim of this study was to investigate the microplastic accumulation in the wedge clam and in different water samples (seawater and purged water) in the Tyrrhenian Coast from September to June. The microplastics found were characterized by color, shape, and polymer type through micro-FTIR. For the first time, the microplastic contamination in wedge clams of the Mediterranean Sea was recorded. In September was recorded the highest concentration of microplastics in wedge clams (0.56 MPs/individual). Only microfiber shapes of different colors and types of polymers were found in both wedge clams and water samples. Polyethylene terephthalate was the most common polymer in wedge clams, while a diversified composition was found in water samples. The most common size both in wedge clams (42.8%) and water samples (≥50%) was in the range 0.1–1 mm. Our results highlight the presence of microplastics in an edible species widely commercialized in the Mediterranean Basin and the possibility of using this species to assess microplastic pollution.
The energy intensity of mechanical processing depending on the cutting modes on the example of longitudinal turning
Authors:   BMSTU, Moscow, Sundetov M.A. , Mukhambetov S.B. ,   Gagarin State Technical University, Saratov, Kiselyov V.L. ,   BMSTU, Moscow
Published: December 2022

The paper analyzes the impact on the energy intensity of the modes and parameters involved in the cutting process. An example of the energy intensity calculation method is given, considered in the cutting modes obtained by the above methods. The results of the work will allow selecting the most energy-intensive cutting modes at the stage of technological preparation of production.
Determination of the number of stripping passes when cutting metric threads on a shaft in a three-cam chuck
Authors:   BMSTU, Moscow, Tuzhilkin V. A. , Brylev A. V. ,   BMSTU, Moscow
Published: December 2022

The paper conducts theoretical studies of literary sources containing a theoretical definition of the components of cutting forces, cutting depths for each of the passes when threading and tolerances for a given degree of accuracy. As a result of the study, a method for determining the number of stripping passes when cutting metric threads was revealed.
Methods of programming of CNC machines
Authors:   Bauman Moscow State Technical University, Moscow, Yudachev S. S. , Sitnikov S. S. ,   Bauman Moscow State Technical University, Moscow, Monakhov P. A. ,   Bauman Moscow State Technical University, Moscow, Gordienko N. A. ,   Bauman Moscow State Technical University, Moscow
Published: December 2022

Methods of calculating the sine in a programmable logic integrated circuit are considered and investigated. Conclusions are given based on the technical characteristics of the devices and the capacity of a particular method. Models were created in C++ and Verilog languages, worked out and analyzed. The results of the models are presented in the form of graphs. Mathematical calculations are given that make it possible to implement the method of calculating the sine in a programmable logic integrated circuit in the most optimal way from the point of view of using equipment. The synthesis and layout of the equipment were carried out, the area of the crystal occupied by the calculation module is presented in the form of a figure. This work can be used to train students of higher educational institutions in order to familiarize and develop skills of working with FPGAs, as well as modeling and studying the principles of choosing a particular mathematical method, can find its application in the creation and design of real devices in production. Familiarization and study of this radar method are conducted within the walls of one of the leading engineering universities of the Russian Federation — Bauman Moscow State Technical University.
Reasons for the culling of breeding stock of holsteinized Black-and-White cattle depending of age
Authors:   Federal State Budgetary Educational Institution of Higher Education “Ural State Agrarian University”, Russia, Ekaterinburg, Gorelik O. V. , Likhodeevskaya O. E. ,   Federal State Budgetary Educational Institution of Higher Education “Ural State Agrarian University”, Russia, Ekaterinburg
Published: December 2022

The improvement of dairy cattle in the Russian Federation is currently being carried out through the use of the gene pool of the world’s best dairy breed as Holstein. This had a positive effect on the dairy productivity of cows, but led to a decrease in productive longevity. Therefore, the reasons for culling the breeding stock of dairy cattle depending on the part of blood of Holstein breed are of considerable interest. At the same time, it is relevant to study the duration of use of cows in herds with industrial exploitation technology. The purpose of the research was to analyze the reasons for culling holsteinized cows of Black-and-White cattle, depending on age. The data on the reasons for culling cows, taking into account the age of cows in lactations have been presented in the article. It has been established that the most common causes of culling are pathology of metabolism, reproductive system, digestive system, selection criteria (mainly barrenness) and pathology of the mammary gland. The age of cows has a certain influence on the level of culling, which increases in full-aged cows. Young cows drop out of the herd due to the pathology of the reproductive system, breast, metabolism, barrenness and injuries. Thus, it was found that the dynamics of metabolic disorders diff ered rhythmically, then increasing, then decreasing from lactation to lactation. This is especially clearly seen from 1 to 5 lactations, and then this dynamics tended to decrease, slightly increasing by 8 lactation. In general, for culled animals the largest culling from the herd was observed for full-aged cows 65,0 % of the total number of culled, including for 3 and 4 lactations 41,0 %. Culling of young cows for 1 and 2 lactations was 35,0 %.
Onward and Upward: The Future of Nursing Education
Authors: Fruchtl Eileen , Allen Caitlyn
Published: December 2022

As nurses around the globe battled COVID, one inconvenient truth became glaring: There were not enough nurses to provide care. And those shortages will only get worse. Now that we have emerged from the pandemic, nurse educators have become more important than ever. What does future curricula look like? How can technology augment training and staffing? How can we ensure the next generation of nurses is dynamic enough for whatever might come their way? Patient Safety managing editor, Caitlyn Allen, sat down with Cedar Crest College senior instructor Eileen Fruchtl to learn more.
GPs’ willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a factorial randomised trial investigating factors influencing decisions
Authors: Lloyd Kelly E , Hall Louise H , Ziegler Lucy , Foy Robbie , Borthwick Gillian M , MacKenzie Mairead , Taylor David G , Smith Samuel G
Published: December 2022

Background

The National Institute for Health and Care Excellence (NICE) 2020 guidelines recommends aspirin for colorectal cancer prevention for people with Lynch syndrome. Strategies to change practice should be informed by understanding the factors influencing prescribing.

Aim

To investigate the optimal type and level of information to communicate with GPs to increase willingness to prescribe aspirin.

Design and setting

GPs in England and Wales (n= 672) were recruited to participate in an online survey with a 23factorial design. GPs were randomised to one of eight vignettes describing a hypothetical patient with Lynch syndrome recommended to take aspirin by a clinical geneticist.

Method

Across the vignettes, the presence or absence of three types of information was manipulated: 1) existence of NICE guidance; 2) results from the CAPP2 trial; 3) information comparing risks/benefits of aspirin. The main effects and all interactions on the primary (willingness to prescribe) and secondary outcomes (comfort discussing aspirin) were estimated.

Results

There were no statistically significant main effects or interactions of the three information components on willingness to prescribe aspirin or comfort discussing harms and benefits. In total, 80.4% (540/672) of GPs were willing to prescribe, with 19.7% (132/672) unwilling. GPs with prior awareness of aspirin for preventive therapy were more comfortable discussing the medication than those unaware (P= 0.031).

Conclusion

It is unlikely that providing information on clinical guidance, trial results, and information comparing benefits and harms will increase aspirin prescribing for Lynch syndrome in primary care. Alternative multilevel strategies to support informed prescribing may be warranted.
Trends in the registration of anxiety in Belgian primary care from 2000 to 2021: a registry-based study
Authors: Beerten Simon Gabriël , Coteur Kristien , Mamouris Pavlos , Van Nuland Marc , Van Pottelbergh Gijs , Casas Lidia , Vaes Bert
Published: December 2022

Background

Anxiety is frequently encountered in general practice, but figures regarding prevalence and incidence in this healthcare setting remain scarce.

Aim

To provide insight about the trends in prevalence and incidence of anxiety in Belgian general practice, as well as the comorbidities and treatment of anxiety in this context.

Design and setting

Retrospective cohort study using the INTEGO morbidity registration network, with clinical data from over 600 000 patients in Flanders, Belgium.

Method

Trends in age-standardised prevalence and incidence of anxiety from 2000 to 2021 as well as prescriptions in patients with prevalent anxiety were analysed with joinpoint regression. Comorbidity profiles were analysed using the Cochran–Armitage test and the Jonckheere–Terpstra test.

Results

During the 22-year study period, 8451 unique patients with anxiety were identified. The prevalence of anxiety diagnoses rose significantly during this period, from 1.1% in 2000 to 4.8% in 2021. The overall incidence rate rose from 1.1/1000 patient–years (PY) in 2000 to 9.9/1000 PY in 2021. The average chronic disease count per patient increased significantly during the study period, from 1.5 to 2.3 chronic conditions. The most frequent comorbidities in patients with anxiety in 2017–2021 were malignancy (20.1%), hypertension (18.2%), and irritable bowel syndrome (13.5%). The proportion of patients treated with psychoactive medication rose from 25.7% to almost 40% over the study period.

Conclusion

A significantly increasing prevalence and incidence of physician-registered anxiety was found in the study. Patients with anxiety tend to become more complex, with more comorbidities. Treatment for anxiety in Belgian primary care is very dependent on medication.
Application of Population Data Collection in Padasuka Village, Bandung Regency, Based on Website
Authors:   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia, HDP M Zari Yoga , Zidane Gala Aulia ,   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia, Hartaman Reyhan Pradita ,   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia
Published: December 2022

Padasuka Sub-region in Cimenyan District, Bandung Regency tries to give populace organization and common enlistment administrations to the local area as per the standards of the Service Standard Guidelines. To work on the nature of administration, it is important to have an assistance framework in the kelurahan so it can work with the presentation of specialist co-ops in sub-district and further develop the help nature of the mechanical assembly into a modernized framework and work with information assortment/chronicling of populace organization. information. The subsequent framework can be utilized to perform automated information assortment
Game Design For an Environmental-themed 2D Adventure Mobile Game
Authors:   Departemen Desain Komunikasi Visual, Universitas Komputer Indonesia, Indonesia, Prasetyo Muhammad Adhithyas , Pamungkas Chandra Gelar ,   Departemen Desain Komunikasi Visual, Universitas Komputer Indonesia, Indonesia, Luhur Gayuh Budi ,   Departemen Desain Komunikasi Visual, Universitas Komputer Indonesia, Indonesia
Published: December 2022

Game is a game based on technology media, which is currently one of the entertainments today. The development of games has become a technology that can be felt, through computers to cellphones. One of the game media, namely mobile games, is an attraction for gamers (people who play games) now. Game makers are competing to make games interesting and useful for game lovers. The genres presented are also diverse, such as RPG, Open World, Horror, Puzzle, Sport, and others. At this time the design of the mobile game focuses on the slide type game, where the camera in the game moves right and left, and the illustrations presented are 2D. This game takes the topic of the environment, which through the game tries to invite players to preserve, learn, and understand about the environment, presented with the spices of RPG (Role Playing Game) games as well as a strong story presentation
Implementation of E-Voting in The Election of The OSIS Chairman of Smkn 2 Rancaekek
Authors:   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia, Ramadan Muhamad , Laoli Damai Saputra ,   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia, Abdillah Muhammad Rifqu ,   Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia
Published: December 2022

In a school organization called OSIS, in general, there must always be a leader or can be called the chairman of the organization, there is an OSIS organization chairman, which aims to promote and prosper the organization in junior high schools and vocational schools, they also must have leadership structures and when We need a leader who deserves to be elected. Therefore This study aims to implement E- VOTING in the selection of student council leaders at SMKN 2 RANCAEKEK because some of the schools are still elected directly or can also be called by voting using paper. To support the research, we use the waterfall method of software development. The sequence in the waterfall method is very serial starting from the planning process of analysis, design, and implementation of the system. results show that election chairman OSIS this use Besides Fulfill principles, we must follow development technology Information as well as speed up the results of the vote recapitulation. Electronic voting or E-Voting is something from collection voice which normally used election general using electronic media. E-Voting also makes elections easierfor example: no eat the cost, speeds up recapitulation voice, honest, fair, happening transparency, and reduces fraud. Because that paper, discusses the application of E- Voting if it is applied to the field of school organization, namely in schools Vocational High School 2 RANCAEKEK.
SISTEM INFORMASI MANAJEMEN DISTRIBUSI PADA CV. LASUSUA FOUNDATION
Authors: Dirgantara Andika , Widianti Utami Dewi
Published: December 2022

Proses pengiriman barang sering terjadi dengan masalah dengan kelebihan muatan dalam pengiriman serta penataan menentukan penjadwalan pengiriman agar tidak mengalami keterlambatan Berdasarkan permasalahan yang terjadi CV. Lasusua Foundation pemecahan solusinya adalah bagaimana membangun sistem informasi manajemen distribusi untuk menangani masalah kesulitan dalam menentukan penataan dan jumlah barang yang harus dimuat serta perencanaan penjadwalan pengiriman agar tidak lagi terjadi keterlambatan pengiriman. Metode yang digunakan pada sistem yang dibangun yaitu dengan metode POAC (Planning, Organizing, Actuating, Controlling) dan metode Np- Hard Bin Problem untuk menyelesaikan permasalahan optimasi muatan Hasil dari penelitian ini yaitu Np- Hard Bin Problem mampu membantu kepala gudang dalam menyelesaikan permasalahan penentuan optimasi barang dan penjadwalan pengiriman.
PEMBANGUNAN APLIKASI ONE DEVICE PARENTAL CONTROL–MULTI ACCESS LIMITS MENGGUNAKAN FACE IDENTIFICATION
Authors: Damareksa Bina , Hardyanto Chrismikha
Published: December 2022

Selama masa pandemi, penggunaan smartphone di Indonesia oleh anak-anak meningkat pesat. Hal ini dikarenakan proses belajar mengajar dilakukan secara daring. Dari hasil obeservasi, studi literatur dan kuisioner, orang tua perlu mengawasi dan membatasi akses penggunaan smartphone oleh anak, terutama jika digunakan secara berlebihan dan ketika anak meminjam smartphone mereka, karena dapat menimbulkan dampak negatif secara fisik dan psikologis bagi anak bahkan bagi orang tua itu sendiri. Meskipun begitu, banyak orang tua yang membiarkan anak mereka bermain secara bebas dan kurang terkontrol dengan smartphone milik mereka. Hal ini tentunya dapat menyebabkan anak secara tidak sengaja melakukan suatu hal yang tidak semestinya di dalam smartphone. Oleh karena itu, penulis membangun aplikasi One Device Parental Control dengan teknologi age recognition digabung dengan teknologi face identification untuk dapat memberikan rekomendasi aplikasi yang sesuai dengan rentang umur anak yang terdeteksi, dan teknologi kiosk mode yang bisa membantu orang tua dalam membatasi akses penggunaan smartphone oleh anak. Berdasarkan hasil pengujian maka dapat disimpulkan bahwa aplikasi ini mampu membatasi akses penggunaan oleh anak dan dapat memberikan rekomendasi aplikasi yang sesuai bagi anak.
Sistem Monitoring Berkas Pengurusan Akta Jual Beli Di Kecamatan Cipayung Kota Depok Berbasis Website
Authors: Zakaria Ridwan Hawafi , Nurhayati Sri
Published: December 2022

Tujuan dari penelitian ini yaitu membuat sebuah sistem monitoring tracking berkas akta jual beli (AJB) agar terwujudnya efisiensi terhadap pengurusan setiap berkas AJB dan mengurangi resiko tumpang tindih data. Saat ini pengelolaan data terhadap setiap berkas AJB di Kecamatan Cipayung masih belum efisien, belum adanya dokumentasi atau monitoring sudah sampai tahap apa pengurusan berkas saat ini karena beberapa faktor dapat menyebabkan keterlambatan setiap pengurusan berkas AJB. Metode yang digunakan untuk pencarian data setiap pengurusan berkas AJB adalah metode Sequential Searching yang didasarkan pada konsep pencarian data secara urut dari depan ke belakang atau dari awal sampai akhir berdasarkan key yang dicari dalam array 1 dimensi. Adapun kriteria yang digunakan pada pencarian metode Sequential Searching yaitu no. referensi pada saat pendaftaran awal dan no. akta untuk arsip lama berdasarkan urutan dan tahun yang akan menjadi key. Analisis pembuatan aplikasi menggunakan pendekatan objek dengan tools UML (Unified Modeling Language). Dari hasil pengujian yang sudah dilakukan secara fungsional aplikasi sudah berjalan sesuai dengan analisis kebutuhan yang dilakukan, aplikasi juga sudah memberikan informasi untuk masyarakat mengenai sudah sampai tahap apa perkembangan dalam pengurusan berkas AJB dan untuk petugas lebih dipermudah dengan pencarian arsip secara online untuk memvalidasi setiap berkas.
Exploring Church Staff Knowledge of Trauma and Trauma-Informed Care
Authors: Guiking Kylie , Jacob Anupama
Published: December 2022

Trauma can affect an individual in various ways that differ in severity. Trauma-informed care within church settings can be beneficial to those seeking healing and guidance from the faith community. Drawing on data collected from surveys, the main purpose of this one-shot case study is to examine church staff’s knowledge of trauma and appropriate ways to respond to individuals experiencing or displaying symptoms of trauma. Findings revealed that a majority of staff defined trauma as a negative emotional or psychological experience and identified family dynamics and life events as two key factors contributing to trauma. However, staff desired additional training to enhance their ability to respond appropriately to individuals showing signs of trauma or sharing about a trauma experience. Findings will guide the development of staff training on trauma-informed care within church settings as well as strategies to integrate faith and social work practice in the church setting.
Love Your Neighbor Collaborative: A Multi-Sector Collaborative to Target Health Disparities for Vulnerable Populations
Authors: Costello Jennifer R.
Published: December 2022

The Love Your Neighbor Collaborative (LYNC) is a multi-sector collaborative of nonprofit community-based organizations, faith communities, educational institutions, local government, and local supportive businesses to target health disparities for the vulnerable population of individuals in homelessness, and near homelessness, throughout the city of Riverside, California.. The goal of LYNC  is to reduce and prevent homelessness by building a coalition of RAOs, academic institutions, and nonprofit organizations to work collaboratively with the city of Riverside to create a stronger, more integrated collective effort resourcing those who are in homeless situations or, at risk of losing their home.
La parité URSS-USA. Définition et problèmes
Authors: Cartigny Claude
Published: December 2022

The strategic balance between USSR and USA . Definition and problems.

A state of balance has been established in the strategic relation between USSR and USA. This balance is the result of a long historical evolution and has required huge efforts of the USSR, which, at the beginning, was in a position of real inferiority. The political «détente» has been favoured by it, but the lack of military «détente» introduces in this balance elements of instability which make the international situation more dangerous. The incapacity of the United States to break the balance in spite of their efforts allows, however, to maintain the risks within certain limits and to hope that a pacific treatement of the historical conflict between imperialism and socialism will interfere.
La faillite économique de la dictature fasciste chilienne
Authors: Alvarez U.-V.
Published: December 2022

L’objet de cet article est d’étudier les conséquences du modèle économique ultra-libéral appliqué par la dictature depuis 1975 et fondé sur les principes du «libéralisme» de l’Ecole de Chicago. L’auteur décrit également l’action engagée par les forces démocratiques et d’opposition au régime pour rétablir la démocratie et insiste sur la notion de droit à la rébellion.
Rente pétrolière et migrations de travail au Moyen-Orient. Le cas de l’Egypte
Authors: Longuenesse Elisabeth
Published: December 2022

Renta del petroleo y migraciones de los trabajadores en el Oriente Medio. El caso de Egipto.

Fenómeno brutal, las migraciones de mano de obra en el Oriente Medio tuvieron efectos masivos, diversos e no controlados en los paises de acogida (el Golfo), como en los paises de origen. La emigración concierne a 15 % de los trabajadores Egipcios y toca a todas las cualificaciones, poniendo en movimiento flujos de ingresos importantes que modifîcan los tipos de consumo y conferan a las mujeres un papel social incrementado. La baja de la renta del petroleo tendra como consecuencia una disminución de los flujos de migración.
L’évolution de la résistance palestinienne depuis 1967
Authors: Picaudou Nadine
Published: December 2022

Du tournant à plusieurs titres décisif de 1967 à l’après-82, N. Picaudou évoque les grandes étapes de la résistance palestinienne, de la formation et du rôle de son organisation, l’OLP, à travers la dialectique de l’affirmation d’une résistance nationale (résistance nationale, souveraineté nationale, Etat national palestinien...) et de ses relations avec les Etats et peuples arabes (dans le cadre du mythe de «l’unité arabe», dans l’élan de la reconnaissance d’un peuple résistant à l’occupation et au «défi» sionistes, dans le cadre des engagements et désengagements des Etats dans le conflit).
Les forces de paix en Israël
Authors: Avran Isabelle
Published: December 2022

Las fuerzas pacifist as en Israel.

1982 fue el ano del empiezo de una guerra de Israel contra el Libano y de la esperanza de un desarollo sin precedente del movimiento paciflsta en Israel. La autora se pregunta si, a pesar de sus presentes divisiones, las fuerzas de paz estan capaces de reunir una población harta de la guerra, cuando el racismo y el fascismo se extenden en toda la sociedad de Israel ¿ Que tipo de paz, cuales posibilidades de reconocimiento del derecho del pueblo palestino a un estado independiente, cuales posibilidades de negociar con la OLP pueden enfocarse ?
Technique de pointe, robotique et initiative en RDA
Authors: Laveau Paul
Published: December 2022

160 robots industriels en 1980, 57 000 actuellement : l’adoption massive des technologies de pointe en RDA tient à des conditions générales favorables, mais aussi à des pressions subies et des nécessités économiques incontournables. Le développement et l’insertion des robots supposèrent une série de productions nouvelles, une sensibilisation et une initiation de masse. Les conséquences, (en RDA et dans la communauté socialiste) ne sont pas minces : questions du plein emploi, des motivations, de l’initiative. La greffe des robots sur l’économie de la RDA semble une réussite, vécue sans inquiétude ni déchirement.
Les mouvements armés de libération nationale du Tiers-monde
Authors: Ziegler Jean
Published: December 2022

Having shown that the MNL constitute radically new formations constantely decried and slandered, the author suggests that one cannot judge their efforts in the building of their nations after having assumed power, without considering the peculiar difficulties of these countries.