bluuebunny/crossref_metadata_2025 huggingface dataset:
Substrate utilisation of cultured skeletal muscle cells in patients with CFS
Authors: Tomas Cara , Elson Joanna L. , Newton Julia L. , Walker Mark
Published: October 2020

Chronic fatigue syndrome (CFS) patients often suffer from severe muscle pain and an inability to exercise due to muscle fatigue. It has previously been shown that CFS skeletal muscle cells have lower levels of ATP and have AMP-activated protein kinase dysfunction. This study outlines experiments looking at the utilisation of different substrates by skeletal muscle cells from CFS patients (n = 9) and healthy controls (n = 11) using extracellular flux analysis. Results show that CFS skeletal muscle cells are unable to utilise glucose to the same extent as healthy control cells. CFS skeletal muscle cells were shown to oxidise galactose and fatty acids normally, indicating that the bioenergetic dysfunction lies upstream of the TCA cycle. The dysfunction in glucose oxidation is similar to what has previously been shown in blood cells from CFS patients. The consistency of cellular bioenergetic dysfunction in different cell types supports the hypothesis that CFS is a systemic disease. The retention of bioenergetic defects in cultured cells indicates that there is a genetic or epigenetic component to the disease. This is the first study to use cells derived from skeletal muscle biopsies in CFS patients and healthy controls to look at cellular bioenergetic function in whole cells.
DDX3 DEAD-box RNA helicase (Hel67) gene disruption impairs infectivity of Leishmania donovani and induces protective immunity against visceral leishmaniasis
Authors: Pandey Satish Chandra , Pande Veena , Samant Mukesh
Published: October 2020

Visceral leishmaniasis (VL) is a vector-borne disease caused by the digenetic protozoan parasiteLeishmania donovanicomplex. So far there is no effective vaccine available against VL. The DDX3 DEAD-box RNA Helicase (Hel67) is 67 kDa protein which is quite essential for RNA metabolism, amastigote differentiation, and infectivity inL. major and L. infantum. To investigate the role ofHel67in theL. donovani, we createdL. donovanideficient in theHel67. Helicase67 null mutants (LdHel67−/−) were not able to differentiate as axenic amastigotes and were unable to infect the hamster. So, we have analyzed the prophylactic efficacy of theLdHel67−/−null mutant in hamsters. TheLdHel67−/−null mutant based candidate vaccine exhibited immunogenic response and a higher degree of protection againstL. donovaniin comparison to the infected control group. Further, the candidate vaccine displayed antigen-specific delayed-type hypersensitivity (DTH) as well as strong antibody response and NO production which strongly correlates to long term protection of candidate vaccine against the infection. This study confirms the potential ofLdHel67−/−null mutant as a safe and protective live attenuated vaccine candidate against visceral leishmaniasis.
Objective analysis of perfluoropropane tamponade area after pars plana vitrectomy using ultra-widefield fundus stereographic projection images
Authors: Choi Mihyun , Hong Suji , Yun Cheolmin , Kim Seong-Woo
Published: October 2020

To objectively analyze the gas tamponade area in patients with different concentrations of perfluoropropane (C3F8) after pars plana vitrectomy (PPV), retrospective analysis was performed in patients diagnosed with retinal detachment or macular hole and underwent PPV with C3F8 tamponade of two concentrations (14% and 20%). The ultra-widefield fundus (UWF) images at one and 10 days and four weeks postoperatively were corrected using stereographic projection to adjust peripheral distortion. The gas–fluid interface curvatures were delineated using UWF stereographic projection images, and the gas–fluid area ratio and estimated gas area were calculated at each concentration. Among 65 eyes, 30 were in the 14% group and 35 were in the 20% group. The gas–fluid area ratio was 0.71 in the 14% group and 0.83 in the 20% group at 10 days (p = 0.046) and 0.27 and 0.45, respectively, at four weeks postoperatively (p < 0.001). The estimated gas area was 52.56 and 60.82 mm2 at 10 days (p = 0.025) and 19.83 and 33.86 mm2 at four weeks (p < 0.001). The gas tamponade areas were objectively shown to be greater under the 20% concentration than the 14% concentration of C3F8 at 10 days and 4 weeks postoperatively using UWF stereographic projection images.
Quantitative analysis of choroidal vasculature in polypoidal choroidal vasculopathy using ultra-widefield indocyanine green angiography
Authors: Ryu Gahyung , Moon Cheolwon , van Hemert Jano , Sagong Min
Published: October 2020

Polypoidal choroidal vasculopathy (PCV) is a common choroidal vascular disease particularly in Asians. However, the underlying pathogenesis of PCV is still yet to be fully elucidated, and the correlation between choroidal vasculature and treatment response of PCV are poorly understood. Accordingly, we sought to find clues to understand the pathogenesis and prognosis of PCV by quantitatively evaluating choroidal vasculature from the entire fundus using ultra-widefield (UWF) indocyanine green angiography (ICGA). In this study, 32 eyes from 29 patients with treatment naïve PCV and 30 eyes from 30 healthy control participants were enrolled. Choroidal vascular density (CVD) of PCV eyes was higher than normal eyes in majority regions including the periphery. CVD was positively correlated with choroidal thickness and choroidal hyperpermeability, supporting that the pathogenesis of PCV may include choroidal congestion and dilatation. Thicker choroid and higher CVD were also correlated with poor treatment response after anti-VEGF injections. The CVD, quantified from UWF ICGA can also be used as an effective image biomarker to predict the treatment response in PCV.
Severe preeclampsia is associated with a higher relative abundance of Prevotella bivia in the vaginal microbiota
Authors: Lin Chia-Ying , Lin Chiao-Yun , Yeh Yuan-Ming , Yang Lan-Yan , Lee Yun-Shien , Chao Angel , Chin Chia-Yin , Chao An-Shine , Yang Chia-Yu
Published: October 2020

We sought to compare the vaginal microbiota profiles of Taiwanese women with severe preeclampsia (SPE) and normotensive control pregnancies. In a discovery cohort, vaginal swab samples and paired blood specimens were simultaneously obtained at the time of caesarean delivery from 30 women with SPE and 30 controls. The composition of vaginal microbiota was characterised by 16S ribosomal RNA gene sequencing of the V3–V4 region. Results were subsequently validated by real-time qPCR. We sought confirmation of our findings in an expanded cohort consisting of 58 women with SPE and 55 controls. In both the discovery and confirmation cohorts, women with SPE had higher relative abundance of Prevotella bivia in their vaginal microbial community (P = 0.006 and 0.011, respectively). Plasma levels of tumour necrosis factor alpha (TNF-α) were higher when compared with controls (P = 0.031) in the confirmation cohort. Three variables (vaginal Prevotella bivia, plasma TNF-α, and body mass index [BMI]) were included in a prediction panel for SPE. Of these, BMI was the most predictive variable. The area under the curve (AUC) of predicted probability values for the three-variable panel revealed that it can discriminate between SPE and normotensive pregnancies with good accuracy (AUC = 0.797, P < 0.001). We conclude that enrichment of Prevotella bivia in vaginal microbiota, which is tightly regulated by BMI, may be involved in the pathogenesis of SPE.
Single-biomolecule Interface for Advanced Single Molecular Sensors
Authors: Li Meng-Yin , Hu Zheng-Li , Wang Ya-Qian , Li Shuang , Yang Jie , Qiu Kaipei , Long Yi-Tao
Published: October 2020

In this chapter, we introduce the biological membrane protein-based single-biomolecule interface for single molecule sensing, including DNA and protein detection, using synergic effects from steric volume exclusion and weak interactions between the nanopore and the analyte. More attentions will be focused on the state-of-art detection strategies for the measurement of a variety of biomolecules via nanopore electrochemistry by the selected experimental case studies, in particular for tracing short-lived metastable conformation and recognition of multiple targets for the promising clinical diagnosis. This chapter selects experimental cases in an α-hemolysin nanopore and an aerolysin nanopore to demonstrate the sensing ability of biological nanopores in detail.
Kinetic analysis of an enzymatic hydrolysis of p-nitrophenyl acetate with carboxylesterase by pressure-assisted capillary electrophoresis/dynamic frontal analysis
Authors: Mine Masanori , Matsumoto Naoya , Mizuguchi Hitoshi , Takayanagi Toshio
Published: October 2020

An enzymatic hydrolysis of p-nitrophenyl acetate with carboxylesterase was analyzed by capillary electrophoresis/dynamic frontal analysis (CE/DFA).
Amorphous-MoO3−x/MoS2 heterostructure: in situ oxidizing amorphization of S-vacancy MoS2 for enhanced alkaline hydrogen evolution
Authors: Wu Wenzhuo , Niu Chunyao , Tian Qingyong , Liu Wei , Niu Guowei , Zheng Xiaoli , Li Chong , Jia Yu , Wei Cong , Xu Qun
Published: October 2020

Amorphous-MoO3−x/MoS2 heterostructure prepared by in situ oxidizing amorphization of S-vacancy MoS2 enables the acceleration of water dissociation and alkaline hydrogen evolution.
Structure-based lead optimization of herbal medicine rutin for inhibiting SARS-CoV-2's main protease
Authors: Huynh Tien , Wang Haoran , Luan Binquan
Published: October 2020

Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic with very limited specific treatments.
Solvent effects on triplet–triplet annihilation upconversion kinetics of perylene with a Bodipy-phenyl-C60photosensitizer
Authors: Wei Yaxiong , Wang Ye , Zhou Qiaohui , Zhang Song , Zhang Bing , Zhou Xiaoguo , Liu Shilin
Published: October 2020

Solvent viscosity and polarity show a profound effect on the triplet–triplet annihilation (TTA) upconversion kinetics of perylene with Bodipy-phenyl-C60as the triplet photosensitizer.
Temperature control in DRIFT cells used for in situ and operando studies: where do we stand today?
Authors: Melián-Cabrera Ignacio
Published: October 2020

Heat transfer limitations in diffuse-reflectance-infrared-Fourier-transform-spectroscopy cells, which can affect the measurement in spectrokinetic studies, have been appraised.
Low-temperature hydrogen production from methanol over a ruthenium catalyst in water
Authors: Awasthi Mahendra K. , Rai Rohit K. , Behrens Silke , Singh Sanjay K.
Published: October 2020

Efficient conversion of methanol to hydrogen gas and formate with an appreciably high TOF and TON is achieved over the in situ generated ruthenium catalyst in water at low temperature.
A TiO2/Nb2O5·nH2O heterojunction catalyst for conversion of glucose into 5-hydroxymethylfurfural in water
Authors: Huang Fangmin , Jiang Tianying , Xu Xincheng , Chen Lu , Laurenczy Gabor , Fei Zhaofu , Dyson Paul J.
Published: October 2020

A series of water-tolerant Lewis acidic TiO2/Nb2O5·nH2O heterojunction catalysts with different Ti : Nb ratios have been prepared and investigated in the conversion of glucose into HMF in water.
Water soluble ionic Co(ii), Cu(ii) and Zn(ii) diimine–glycinate complexes targeted to tRNA: structural description, in vitro comparative binding, cleavage and cytotoxic studies towards chemoresistant prostate cancer cells
Authors: Zehra Siffeen , Gómez-Ruiz Santiago , Siddique Hifzur R. , Tabassum Sartaj , Arjmand Farukh
Published: October 2020

Four new water soluble Co(ii), Cu(ii) and Zn(ii) ionic metal complexes were synthesized as cytotoxic agents against chemoresistant prostate cancer cells.
UiO-66 derivatives and their composite membranes for effective proton conduction
Authors: Feng Lu , Hou Hao-Bo , Zhou Hong
Published: October 2020

As newly emerging proton-conducting materials, metal–organic frameworks (MOFs) have been attracting wide attention in the field of proton exchange membrane fuel cells.
The immunoenhancement effects of starfishAsterias rollestonipolysaccharides in macrophages and cyclophosphamide-induced immunosuppression mouse models
Authors: Liu Yingjuan , Wu Xiaolin , Wang Yue , Jin Weihua , Guo Yunliang
Published: October 2020

The polysaccharide (SF-2) from starfishAsterias rollestonienhanced immune response in macrophages and cyclophosphamide-induced immunosuppression mouse models.
Factors impacting lipid digestion and nutraceutical bioaccessibility assessed by standardized gastrointestinal model (INFOGEST): oil
Authors: Tan Yunbing , Zhang Zhiyun , Liu Jinning , Xiao Hang , McClements David Julian
Published: October 2020

INFOGEST gastrointestinal model used to study impact of oil droplet size on digestion and bioaccessibility.
Deterministic droplet codingviaacoustofluidics
Authors: Zhang Peiran , Wang Wei , Fu Hai , Rich Joseph , Su Xingyu , Bachman Hunter , Xia Jianping , Zhang Jinxin , Zhao Shuaiguo , Zhou Jia , Huang Tony Jun
Published: October 2020

Encoding information into the serial sequence of micro-droplet lengthsviaacoustofluidic dispensing.
Significant enhancement of the thermoelectric properties of CaP3 through reducing the dimensionality
Authors: Zhu Xue-Liang , Liu Peng-Fei , Wu Yi-Yuan , Zhang Ping , Xie Guofeng , Wang Bao-Tian
Published: October 2020

Through first-principles calculations and using the Boltzmann transport equation, we explore the thermoelectric (TE) properties of CaP3 from the three-dimensional (3D) bulk form to a two-dimensional (2D) monolayer and find that the TE properties are greatly enhanced by reducing the dimensionality.
Optically detected magnetic resonance in CdSe/CdMnS nanoplatelets
Authors: Tolmachev Danil O. , Ivanov Vitalii Yu. , Yakovlev Dmitri R. , Shornikova Elena V. , Witkowski Bartłomiej , Shendre Sushant , Isik Furkan , Delikani Savas , Demir Hilmi Volkan , Bayer Manfred
Published: October 2020

ODMR in CdSe/CdMnS nanoplatelets is observed in intensity and polarization response.
Recent advances in the development and applications of nonconventional luminescent polymers
Authors: Bauri Kamal , Saha Biswajit , Banerjee Arnab , De Priyadarsi
Published: October 2020

Recently, nonconventional luminescent polymers (NLPs) have emerged as the most sought-after alternative luminescent materials. This review provides a thorough description of the importance and applications of each class of state-of-the-art NLPs.
Site-selective and diastereoselective functionalization of α-amino acid and peptide derivatives via palladium-catalyzed sp3 C–H activation
Authors: Zhang Ming , Zhong Shengliang , Peng Yiyuan , Jiang Jianwen , Zhao Yongli , Wan Changfeng , Zhang Zhenming , Zhang Rongli , Zhang Ai Qin
Published: October 2020

This review introduces palladium-catalyzed C–H functionalization of amino acids and peptides.
Generation of (Z)-β-alkenyl alkylsulfones via a copper-catalyzed decarboxylative alkylsulfonylation
Authors: Zhu Tonghao , Rojsitthisak Pornchai , Wu Jie
Published: October 2020

A copper-catalyzed three-component reaction of acrylamides, sulfur dioxide and phenyliodine(iii) dicarboxylates is developed. The conversion using phenyliodine dicarboxylates as alkyl radical precursors provides diverse (Z)-β-alkenyl alkylsulfones.
Mechanical behavior of SiNC layers on PDMS: effects of layer thickness, PDMS modulus, and SiNC surface functionality
Authors: Izadi Alborz , Sinha Mayank , Papson Cameron , Roccabianca Sara , Anthony Rebecca
Published: October 2020

Experimental/theoretical estimations of the neo-Hookean coefficients of SiNC layers on PDMS show a dependence on layer thickness as well as on the modulus of the PDMS, but not on the surface functionality of the SiNCs.
Selection of a suitable ZIF-8/ionic liquid (IL) based composite for selective CO2 capture: the role of anions at the interface
Authors: Thomas Anoopa , Ahamed Rafiq , Prakash Muthuramalingam
Published: October 2020

The interfacial stability of hydrophilic/hydrophobic IL incorporated ZIF-8 is identified and the CO2 selectivity depends on the fluorinated anions in the IL.
In situ transformation of bismuth metal–organic frameworks for efficient selective electroreduction of CO2 to formate
Authors: Yuan Wei-Wen , Wu Jian-Xiang , Zhang Xiang-Da , Hou Shu-Zhen , Xu Ming , Gu Zhi-Yuan
Published: October 2020

After in situ transformation from a bismuth–carboxylate MOF, MOF-derived Bi2O2CO3 possesses superior activity, selectivity and stability in the electroreduction of CO2 to formate.
Trifunctional modification of individual bacterial cells for magnet-assisted bioanodes with high performance in microbial fuel cells
Authors: Jiang Yujing , Li Pingping , Wang Yuanyuan , Jiang Li-Ping , Song Rong-Bin , Zhang Jian-Rong , Zhu Jun-Jie
Published: October 2020

Trifunctional modification of individual bacterial cells results in fast start-up and high stability and output of microbial fuel cells.
Submillimeter Wave Instrument radiometry of the Jovian icy moons
Authors: Ilyushin Y. A. , Hartogh P.
Published: October 2020

Context. We address the issue of remote sensing of the surfaces of Galilean icy moons. We investigate the prospects for retrieval of the physical parameters of the surface of the Jovian icy moons from submillimeter wave radiometry data.

Aims. We show that the model parameters could not be completely retrieved from the polarized radiometry data, but some of their combinations can be effectively constrained.

Methods. The polarized radiative transfer in lossy porous ice was numerically simulated. A Bayesian maximum likelihood retrieval algorithm was developed and tested on the simulated data in a wide range of variation of the model parameters. The uncertainty of the retrievals was evaluated with the Cramer-Rao bounds. We established the combinations of model parameters that can be effectively constrained from the measured data.

Results. We reveal that the effective scatterer size can be reliably constrained for a range of values where the scattering asymmetry parameter uniquely depends on the wave parameter, and for relatively high values of the single scattering albedo, for which the scattering in the medium is significant. Similarly, the domains of reliable retrieval of the single scattering albedo and thermal skin depth are established.
It has to be cool: Supergiant progenitors of binary black hole mergers from common-envelope evolution
Authors: Klencki Jakub , Nelemans Gijs , Istrate Alina G. , Chruslinska Martyna
Published: October 2020

Common-envelope (CE) evolution in massive binary systems is thought to be one of the most promising channels for the formation of compact binary mergers. In the case of merging binary black holes (BBHs), the essential CE phase takes place at a stage when the first BH is already formed and the companion star expands as a supergiant. We aim to decipher the kinds of BH binaries with supergiant companions that could potentially evolve through and survive a CE phase. To this end, we compute envelope binding energies from detailed massive stellar models at different evolutionary stages and metallicities. We make multiple physically extreme choices of assumptions that favor easier CE ejection as well as account for recent advancements in mass-transfer stability criteria. We find that even with the most optimistic assumptions, a successful CE ejection in BH binaries is only possible if the donor is a massive convective-envelope giant, namely a red supergiant (RSG). The same is true for neutron-star binaries with massive companions. In other words, pre-CE progenitors of BBH mergers are BH binaries with RSG companions. We find that because of its influence on the radial expansion of massive giants, metallicity has an indirect but a very strong effect on the chemical profile, density structure, and the binding energies of RSG envelopes. Our results suggest that merger rates from population-synthesis models could be severely overestimated, especially at low metallicity. Additionally, the lack of observed RSGs with luminosities above  log(L/L⊙) ≈ 5.6 − 5.8, corresponding to stars withM ≳ 40 M⊙, puts into question the viability of the CE channel for the formation of the most massive BBH mergers. Either such RSGs elude detection due to very short lifetimes, or they do not exist and the CE channel can only produce BBH systems with total mass ≲50 M⊙. Finally, we discuss an alternative CE scenario in which a partial envelope ejection is followed by a phase of possibly long and stable mass transfer.
Optimal boundary control for steady motions of a self-propelled body in a Navier-Stokes liquid
Authors: Hishida Toshiaki , Silvestre Ana Leonor , Takahashi Takéo
Published: October 2020

Consider a rigid body 𝒮 ⊂ ℝ3 immersed in an infinitely extended Navier-Stokes liquid and the motion of the body-fluid interaction system described from a reference frame attached to 𝒮. We are interested in steady motions of this coupled system, where the region occupied by the fluid is the exterior domain Ω = ℝ3 \ 𝒮. This paper deals with the problem of using boundary controls v*, acting on the whole ∂Ω or just on a portion Γ of ∂Ω, to generate a self-propelled motion of 𝒮 with a target velocity V (x) := ξ + ω × x and to minimize the drag about 𝒮. Firstly, an appropriate drag functional is derived from the energy equation of the fluid and the problem is formulated as an optimal boundary control problem. Then the minimization problem is solved for localized controls, such that supp v*⊂ Γ, and for tangential controls, i.e, v*⋅ n|∂Ω = 0, where n is the outward unit normal to ∂Ω. We prove the existence of optimal solutions, justify the Gâteaux derivative of the control-to-state map, establish the well-posedness of the corresponding adjoint equations and, finally, derive the first order optimality conditions. The results are obtained under smallness restrictions on the objectives |ξ| and |ω| and on the boundary controls.
Study on the High-performance Composite Wall Panel Envelop of Building and its Relevant Joint Construction
Authors: Gao Yuxin , Cheng Baojun , Ma Pengfei , Shi Boyuan , Kang Shengrong , Tu Yulin
Published: October 2020

Aiming at the general problems of envelop wall panel about the existing building, such as large surface density, low strength, poor service performance and high maintenance cost, a kind of high-performance composite wall panel is proposed in this paper. This wall panel takes high toughness cement-based composite material as shell and inorganic light thermal insulation material as core part. Its surface density equals to or is less than 70 kg/m2, heat transfer coefficient equals to or is less than 1 W/ (m2·K ), and the minimum bending failure load equals to or is more than 8 times of wall panel weight. Combined with the characteristics of high-performance composite wall panel, the “removable connection system” and “beveled tongue and groove type” joint structure are proposed to realize the construction of high-performance composite wall panel without moisture, nondestructive free disassembly and green recycling.
Research Progress of Buton Rock Asphalt in Road Pavement Materials
Authors: Yang Qiao
Published: October 2020

A large number of domestic and international literatures have studied the pavement performance of composite modification of Buton rock asphalt and different asphalt modifiers. It is found that basalt blending can greatly improve the performance in an all-round way, in which high-temperature stability and low-temperature cracking resistance have superimposed effect. Waste rubber powder blending has little overall performance improvement. With diatomite blending the performance can exceed SBS modified asphalt. The research on composite modification of Buton rock asphalt still needs further study.
Experimental Study on Performance of Foamed Magnesium Slag Cement
Authors: Guo Chen , Ma Jianxun , Dai Yuheng , Niu Rui
Published: October 2020

Magnesium slag is an industrial waste residue produced in magnesium smelting. Its chemical composition is similar to Portland cement and has potential activity. After the magnesium slag is foamed, it can be made into a new type of lightweight material, and its forming, mechanical and physical properties were closely related to dry material formula, water-cement ratio and foaming agent amount. In this paper, experiments were carried out to find the ingredients and processes suitable for the forming of foamed magnesium slag, making it have certain mechanical and physical properties at the same time.
Study on Damage Characteristics of Fiber Concrete under Acid Rain Erosion
Authors: Wu Duo
Published: October 2020

Concrete structure will be corroded under acid rain scouring and soaking for a long time, which has a great influence on its durability life. In order to further study the damage characteristics of fiber reinforced concrete under acid rain erosion, the formation mechanism of acid rain and its influence on the corrosion and deterioration of concrete and fiber materials were analyzed in this paper. Taking basalt fiber concrete as an example, the characteristics such as porosity, compressive strength and mechanical indexes were studied and analyzed. Moreover, the reasons for the optimal fiber content was briefly analyzed. The results show that the inner structure of basalt concrete mixed with 0.1% fiber was the most stable and the corrosion resistance was the most satisfying.This conclusion has certain reference significance for the corrosion damage research of fiber reinforced concrete.
Analysis of the bolt performance with shear force
Authors: Mao Dawei , Chen Yu
Published: October 2020

The bolt anchorage performance with shear force has been analysed by analytical method in this paper. By coding in Matlab, the loop and the judgment statement can be used to control the displacement angle. The force-displacement curve of the analysis model from the beginning of loading to the failure of the bolt under a certain displacement loading angle is obtained. In the test and field, the values of displacement and force before failure and the load-displacement curves before the peak value can be obtained by using the program with the parameters. The bolt deformation in different strength surrounding rock mass and the anchoring influence of the rock bolt with different diameters have been studied. The resultant displacement increases linearly with the increase of the bolt, and the resultant force increases exponentially with the increase of the bolt.
Finite element analysis of bolt shear connection of steel-concrete composite structure
Authors: Pan Zhishun
Published: October 2020

Bolted shear connectors are an important component to ensure that steel-concrete composite structures can work together. High-strength bolt shear connectors can replace traditional stud connectors because of their disassembly, good mechanical performance and fatigue resistance. It applied to steel-concrete composite structure. In order to study the influencing factors of the bearing capacity of high-strength bolted shear connectors, this paper uses ABAQUS finite element simulation software as a research tool to establish a reasonable finite element model to study the influence of bolt strength, bolt diameter and concrete strength on bolted shear connectors. Studies have shown that increasing the diameter, strength, and concrete strength of bolted connections can effectively increase the bolt’s shear capacity.
Simulation of the newly-built temporary cofferdam stability under the regular wave condition
Authors: Liu Wenbin
Published: October 2020

The lateral cyclic wave force challenges the newly-built temporary cofferdam seriously. This paper simulated and assessed the movement of the plugged-in steel cylinder affected by the regular wave force with finite element method. The FEM analysis was conducted for an actual case, and the conclusions may show its advantages in the design work.
Research on residual shear strength of surrounding rock base on elastic-plastic softening model
Authors: Zhou Heng , Zhang Ying , Liu Bo , Di Shengjie , Huang Peng
Published: October 2020

With the rapid development of infrastructure construction, the edge shape analysis of underground chamber excavation in water conservancy and hydropower projects has received more and more attention. This paper takes an underground chamber of a hydropower project as the research object and uses an ideal elastoplastic stress-strain softening model to study the relationship between deformation, stress, plastic zone and strength parameters. The results show that the value of each shear strength parameter has a significant effect on the distance of the plastic zone, and the calculation result may provide a basis for the design.
Contrastive analysis of dynamic response of tailings dam with and without geofabriform by shaking table model test
Authors: Li Qiaoyan , Ma Guowei , Li Ping , Su Zhandong
Published: October 2020

Construction using geofabriform is a new promising technology to build fine grain tailings dam. Large-scale shaking table tests are conducted in this study to investigate the dynamic performances in terms of horizontal acceleration and displacement of the tailings dam with and without geofabriform subject to horizontal earthquakes. Test results indicate that the seismic performance of the tailings dam with geofabriform is significantly better than that of tailings dam without geofabriform. The two types of tailings dams have different failure modes under the action of earthquake. The acceleration amplification factor(Am), vertical displacement and horizontal displacement of the tailings dam with geofabriform under the same seismic acceleration input are smaller than that of the tailings dam without geofabriform, the maximum attenuation amplitude of the Am at the dam slope reaches to 81%. The horizontal displacements of the two types of dams are nonlinearly distributed in the height direction and the geotextile bags of the tailings dam have an upward displacement and are tilted upward. According to the failure mode of the tailings dam with geotextile bags, it is recommended to strengthen the drainage measures and set up anti-slide piles at the bottom of the geotextile bags body to strengthen the tailings dam.
Exploration of Lintong-Chang’an Fault in relation to Lintong Kine of Rapid Rail Rransit in Xi’an city
Authors: Ren Fengwen , Li Baolai , Bian Jumei , Li Chunfeng , Tian Weixin
Published: October 2020

In this paper, the method of combining high-density electrical exploration and shallow seismic exploration is used to explore the Lintong-chang ’an fault in relation to Lintong line of rapid rail transit in Xi’an city. The distribution and activity of the fault are determined, providing a basis for seismic fortification and seismic geological disaster evaluation in the line.
Minimum gas injection of gas drilling while temperature and pressure coupling
Authors: Ju Pengfei , Yang Zhiyi , Li Weixuan , Guo Yong , Zhu Zhongxi
Published: October 2020

Gas drilling technology not only has the advantages of avoiding well leakage, shale hydration expansion,reservoir pollution and other issues, but also can greatly improve the drilling speed 4 to 8 times, it is helpful to timely discover and effectively protect reservoir and improve recovery efficiency and single well production of oil and gas reservoir, especially has important significance for hard strata and dense reservoir exploration. However, there are some problems hindered the promotion of this technology, such as gas is hard to carries cuttings and gas hole blocking. One of the key technologies to solve these problems is the determination of gas volume. Most of today’s literature use formation temperature instead of annulus temperature to calculate minimum gas volume. Owing to gas’ PVT effect, temperature is dramatically influenced by pressure flow velocity, there will be big error if we use formation temperature instead of annulus temperature. Meanwhile, most of traditional minimum gas volume methods use top of the drill collar as key point. In this study, we found that on the top of the drill collar, the carrying kinetic energy of gas is not is not necessarily the minimum, and change of the key position is strongly influenced by wellbore structure and make-up of drill tool. Minimum gas volume determined by applying temperature - pressure coupling calculation is more close to site construction, under the given conditions, error of the minimum gas volume is about 0.4%.
Analysis on the groundwater salt dynamic in a monitoring area in Hetao Irrigation District of Inner Mongolia
Authors: Chengfu Yuan
Published: October 2020

In order to explore the rule of groundwater salt dynamic in Hetao Irrigation District, a typical monitoring area was selected as the research area in Yongji Irrigation Area of Hetao Irrigation District. The groundwater level and groundwater salinity were analyzed during the year and inter-annual variation in 2008-2013. The groundwater level showed an obvious seasonal change trend during the year variation. The groundwater level was at the peak value after spring irrigation and autumn irrigation. The groundwater level was at the low value before melting and autumn irrigation. The groundwater level had an obvious periodicity during the inter-annual variation. The groundwater level could keep a relatively stable for many years. The groundwater salinity showed an obvious seasonal change trend during the year variation. The groundwater salinity was greatly affected by irrigation and had a decreased trend after irrigation. The groundwater salinity had an obvious periodicity during the inter-annual variation and could keep a relatively stable for many years in cultivated land. The groundwater salinity had an increased trend during the inter-annual variation in wasteland. The wasteland was the drainage area for cultivated land. The wasteland had an obvious role in adjusting salt dynamic balance in Hetao Irrigation District.
Design and Construction of the Circular Shape Shaft Using the Reverse Construction Method
Authors: Tang Ziqiang
Published: October 2020

Restricted by the environment and the city’s planning, some pipe jacking used for the HV cable tunnel have to pass through some roads which has been build. Different kind of equipment has certain applicability in the pipe jacking construction procedure, especially with the geological condition, and encountering in the boulder is a common problem in the residual soil or in the strong weathered rock stratum, in this situation, a vertical shaft is needed to remove the boulder. In order to save the site area, a new shaft which is in circular shape is designed, and this paper introduces the main procedure of how to design and construct the new circular shaft. In a Fuzhou HV cable tunnel, the new shape shaft clears away the stone in the clay successfully, and reduces the impact on the ground traffic, the design and construction procedure of the new shaft have been analyzed in this paper, which provides reference for similar construction.
Influence of skirt reinforcement in passive zone on deformation of excavation
Authors: CHEN Peng-fei , GONG Xiao-nan
Published: October 2020

In the design of the excavation protection scheme in the soft soil area, it is often necessary to set up cement-soil mixing piles in the passive area. In this way, the stability requirements of the excavation can be met, and the lateral displacement of the retaining pile can be greatly restricted. This paper uses PLAXIS 3D to establish a excavation model in a soft area, and discusses the influence of various parameters of the passive zone mixing pile on the deformation and force of the excavation. Within a certain range, as the cohesive force or secant modulus or reinforcement width or depth of the reinforcement area increases, the lateral displacement and settlement outside the pit will decrease. But when it exceeds a certain range, the decreasing trend becomes very slow. With the increase of the four parameters of the reinforcement zone, bending moments in opposite directions appear below the bottom of the excavation. Moreover, the value of the bending moment is getting larger and larger. Therefore, considering the force, it is not that the wider and deeper the reinforced zone is, the more advantageous is.
Design of coiled tubing torque reducing device
Authors: Xiong Chao , Guan Zhigang , Jiang Zhenxing , Ye Yuchen , Zhu Zhongxi
Published: October 2020

During the operation of coiled tubing drilling, the power motor will produce reactive torque when it works, which will affect the drilling process. A torque reducing device is designed to counteract the torque by injecting drilling fluid. The device is designed as a short section, connected with cardan shaft and drive shaft, the nozzle of which can be automatically adjusted according to the pump pressure. The flow model of the device is established by SolidWorks software, and then leaded in FLUENT software for simulation. The standard k-epsilon model is used to simulate the operating conditions of 5 nozzle diameters and 2 outlet diameters respectively, and the parameters such as pressure drop, torque and flow rate are obtained. The designed torque reducing device can offset about 30% of the torque generated by the screw drill, and the reactive force of single jet is about 152N. If the jet direction is perpendicular to the axis, it can produce the drilling pressure about 3.4kN. If the direction of the nozzle is aligned with the axis, the effect of pressurization and torsion reduction can be produced simultaneously.
Research on Seismic Vulnerability of Continuous Beam Bridges Based on Incremental Dynamic Analysis Method
Authors: Wang Peizhi
Published: October 2020

The seismic vulnerability of highway continuous girder bridges is analyzed to provide theoretical basis for the study of multi-stage fortification and seismic design of such bridges. Based on the concept of performance seismic design, five performance levels of structures are determined, and the displacement ductility ratio of piers is taken as the performance quantitative index to calculate the damage limit values of bridges in different limit states. On this basis, IDA analysis method is used to calculate 20 subjects. Based on the reliability theory, logarithmic regression fitting analysis is carried out to obtain the seismic vulnerability curve. The theoretical vulnerability curve is indicated that the bridge has good comprehensive seismic performance. Under 0.3 g ground motion, the probability of minor damage, moderate damage and serious damage are 57.9%, 44.7% and 3.6% respectively. The comprehensive seismic performance of bridges and the probability of exceeding the damage status at all levels are reflected in the results, the guiding significance to analysis of the seismic performance of the entire traffic and the formulation of emergency rescue plans.
Study on Safety Coefficient and Failure Face Ratio of Slope with Soft Layer
Authors: Gao Ming-hui , Zhao Jian-qing , Sun Chao , Wang Xiao , Wang Qi-zhi
Published: October 2020

In this paper, the slope with horizontal weak interlayer is taken as the research object, and the safety factor and the location of the failure surface of the slope are calculated by finite element strength reduction method and limit equilibrium method respectively. The results show that when the slope is mixed with soft layer, the positions of the critical failure surfaces calculated by the two methods are quite different, but their safety factors are relatively small. Which method is more accurate needs to be analyzed in combination with the specific conditions of the slope. Through comparative analysis, the calculation efficiency of limit equilibrium method is much higher than that of strength reduction method. The results of this paper provide reliable reference for engineering analysis.
Comparative study on the results of different tensile test methods of artificial frozen soil
Authors: Yu Chang-yi , Lu Ming-yue
Published: October 2020

Tensile strength of frozen soil is an important index for frozen soil engineering design. It is found that uniaxial tensile strength, three-point bending and four-point bending tensile strength values of frozen soil are inconsistent in the test. For this reason, the meso-level numerical method is adopted, assuming that the meso-level material parameters conform to Weibull distribution, and the damage model is adopted, and the macro-level material properties conform to linear elasticity assumption. Uniaxial tensile test, three-point bending tensile test and four-point bending tensile test are respectively simulated. The results show that the difference comes from the non-uniformity of materials. The results of this paper provide effective guidance for frozen soil strength design.
Research on the reinforcement measures of close-parallel tunnels
Authors: Meng Li , Ping Hu , Liang Ma
Published: October 2020

Based on shallow parallel underground tunnel and double-line shield tunnel of Jinan Rail Transit Line R3, this paper proposes two reinforcement measures including bored piles and curtain grouting in the middle of the tunnel, making a numerical analysis and comparison of the reinforcement effect. The results show that the influence of later tunnel construction on the deformation of earlier tunnel can be effectively reduced after taking two reinforcement measures respectively and the reinforcement effect of the bored piles is better.
Research Status and Development Trend of Self-Compacting Concrete technology
Authors: Ning Wenxiang , He Qiang , Gong Jian
Published: October 2020

The definition of self-compacting concrete is briefly introduced. The research process of self-compacting concrete in various countries in the world is studied, from the initial test to the final formation of the preliminary application specification, and it is constantly improved. The mix proportion design, working performance, testing method, application and research status of self-compacting concrete are discussed in detail, and the problems to be solved in the future and the development prospect are prospected
Research progress of key technologies for preparing concrete admixtures by multiple activation of iron-containing tailings
Authors: Gu Xiaowei , Hu Ziyang , Liu Peng , Pang Shuyun , Chi Haofeng
Published: October 2020

Iron tailings are an excellent secondary resource. Reasonable use, it can not only alleviate the problem of resource shortage, but also solve some environmental pollution problems. Therefore, it has a good development prospect. The resource utilization of iron tailings has always been a hot spot of social concern. The article reviews the results achieved by the predecessors. In addition, outlines the method of activation of iron tailings and the influence of its strength and durability as a concrete composite admixture. At last, the prospects of the research on the utilization of iron tailings are put forward.
Discussion on Prefabricated Concrete Structure Design Method under BIM Technology
Authors: Hongyan Wang , Zihong Zhang
Published: October 2020

BIM is a data tool used in various stages of design, construction and management. It can integrate different models of buildings and realize sharing and transmission during the life cycle of the project, ensuring that engineering technicians can access different building information with a correct understanding and real-time response, it lays a good foundation for different participants including design, construction and management to achieve collaborative work. It is very important whether it is to ensure production efficiency, save costs and shorten construction periods. For the newly emerging prefabricated buildings, their structural design will become more efficient, accurate and reasonable due to the introduction of BIM technology.
Analysis of some problems in classification of seabed bottom characteristics using acoustic backscattering intensity
Authors: Jintao FENG , Jingyang BAO , Shaohua JIN , Fumin XIAO , Gang BIAN
Published: October 2020

The backscattering intensity collected by multi beam sonar system and scanning sonar system can be used to classify seabed bottom characteristics. However, there are many problems that have not been solved in the practical application. This paper attempts to sort out and analyze the problems encountered in the classification process and put forward some solutions. The relationship among acoustic image, seabed topography and sediment is analyzed
Landslide susceptibility mapping using machine learning for Wenchuan County, Sichuan province, China
Authors: Yang Xin , Liu Rui , Li Luyao , Yang Mei , Yang Yuantao
Published: October 2020

Landslide susceptibility mapping is a method used to assess the probability and spatial distribution of landslide occurrences. Machine learning methods have been widely used in landslide susceptibility in recent years. In this paper, six popular machine learning algorithms namely logistic regression, multi-layer perceptron, random forests, support vector machine, Adaboost, and gradient boosted decision tree were leveraged to construct landslide susceptibility models with a total of 1365 landslide points and 14 predisposing factors. Subsequently, the landslide susceptibility maps (LSM) were generated by the trained models. LSM shows the main landslide zone is concentrated in the southeastern area of Wenchuan County. The result of ROC curve analysis shows that all models fitted the training datasets and achieved satisfactory results on validation datasets. The results of this paper reveal that machine learning methods are feasible to build robust landslide susceptibility models.
Well-being by Formula? Exploring the Role of Somaesthetics in Making Self-tracking More Sustainable
Authors: Wu Xue , Liao Han-Teng , Zhao Man
Published: October 2020

Self-tracking, a phenomenon which dataify individuals’ daily activities and experiences, presents both opportunities and challenges to understand which factors and in what ways may influence individuals’ health status or well-being. Technology can enhance the era of personal happiness and increase social well-being. We hope to provide a design principle and operational design method to promote the well-being consideration of self-tracking products and technologies. In order to propose such principles and methods, it is necessary to first analyze the key factors of happiness in using self-tracking products. This article proposes “The Self-tracking Sustainability Formula”, which includes three elements as information, well-being drives, and material. Such a formula could possibly conceptually explain the components of a self-tracking product with sustainable potential. On this basis, this paper further explores how self-tracking products can positively influence issues such as environmental protection, personnel management, and friendly social relations from the dimensions of “information” and “well-being drives” to form more sustainable. Production and consumption ecology. This paper argues that, in order to enhance such a process of sustainable well-being, we as user researchers and product designers must design better ways of visualizing and interacting with “datafied well-being”. From the citations of dashboards, we draw upon both the principles of Somaesthetics to propose an “avatar” as the central interface component. An avatar, or a humanized animal image, is proposed to provide a more intuitive understanding of one’s physical, emotional, and social well-being, looking forward to helping self-tracking products become more sustainable by considering sustainable design principles and forms in the design process and motivating users to be more willing to accept sustainability Self-tracking products.
Research on the full life cycle management of the substation Engineering based on Three-Dimensional
Authors: Wu Hailiang , Xing Lin , Liu Zhong , Zhang Wuchen , Cheng Nan , Wang Yamin , Su Jizhi
Published: October 2020

With the development of modern information technology, the three-dimensional design technology is widely applied in the substation engineering design of State Grid Corporation of China, and will run through the whole process of the power grid, effectively promoting the management of the substation engineering full life cycle.This paper analyzes the application scope of three-dimensional design in substation engineering is studied in depth, and the future application development is prospected, which provides a reference for the development direction of three-dimensional design in the future.