bluuebunny/crossref_metadata_2025 huggingface dataset:
Web-Based Warfarin Management (Alfalfa App) Versus Traditional Warfarin Management: Multicenter Prospective Cohort Study
Authors: Chen Wenfei , Chen Jiana , Jiang Shaojun , Wang Chunhua , Zhang Jinhua
Published: July 2024

Background

Poor anticoagulation management of warfarin may lead to patient admission, prolonged hospital stays, and even death due to anticoagulation-related adverse events. Traditional non–web-based outpatient clinics struggle to provide ideal anticoagulation management services for patients, and there is a need to explore a safer, more effective, and more convenient mode of warfarin management.

Objective

This study aimed to compare differences in the quality of anticoagulation management and clinical adverse events between a web-based management model (via a smartphone app) and the conventional non–web-based outpatient management model.

Methods

This study is a prospective cohort research that includes multiple national centers. Patients meeting the nadir criteria were split into a web-based management group using the Alfalfa app or a non–web-based management group with traditional outpatient management, and they were then monitored for a 6-month follow-up period to collect coagulation test results and clinical events. The effectiveness and safety of the 2 management models were assessed by the following indicators: time in therapeutic range (TTR), bleeding events, thromboembolic events, all-cause mortality events, cumulative event rates, and the distribution of the international normalized ratio (INR).

Results

This national multicenter cohort study enrolled 522 patients between June 2019 and May 2021, with 519 (99%) patients reaching the follow-up end point, including 260 (50%) in the non–web-based management group and 259 (50%) in the web-based management group. There were no observable differences in baseline characteristics between the 2 patient groups. The web-based management group had a significantly higher TTR than the non–web-based management group (82.4% vs 71.6%, P<.001), and a higher proportion of patients received effective anticoagulation management (81.2% vs 63.5%, P<.001). The incidence of minor bleeding events in the non–web-based management group was significantly higher than that in the web-based management group (12.1% vs 6.6%, P=.048). Between the 2 groups, there was no statistically significant difference in the incidence of severe bleeding and thromboembolic and all-cause death events. In addition, compared with the non–web-based management group, the web-based management group had a lower proportion of INR in the extreme subtreatment range (17.6% vs 21.3%) and severe supertreatment range (0% vs 0.8%) and a higher proportion in the treatment range (50.4% vs 43.1%), with statistical significance.

Conclusions

Compared with traditional non–web-based outpatient management, web-based management via the Alfalfa app may be more beneficial because it can enhance patient anticoagulation management quality, lower the frequency of small bleeding events, and improve INR distribution.
Preferences for COVID-19 Vaccines: Systematic Literature Review of Discrete Choice Experiments
Authors: Huang Yiting , Feng Shuaixin , Zhao Yuyan , Wang Haode , Jiang Hongbo
Published: July 2024

Background

Vaccination can be viewed as comprising the most important defensive barriers to protect susceptible groups from infection. However, vaccine hesitancy for COVID-19 is widespread worldwide.

Objective

We aimed to systematically review studies eliciting the COVID-19 vaccine preference using discrete choice experiments.

Methods

A literature search was conducted in PubMed, Embase, Web of Science, Scopus, and CINAHL Plus platforms in April 2023. Search terms included discrete choice experiments, COVID-19, and vaccines and related synonyms. Descriptive statistics were used to summarize the study characteristics. Subgroup analyses were performed by factors such as high-income countries and low- and middle-income countries and study period (before, during, and after the pandemic wave). Quality appraisal was performed using the 5-item Purpose, Respondents, Explanation, Findings, and Significance checklist.

Results

The search yield a total of 623 records, and 47 studies with 53 data points were finally included. Attributes were grouped into 4 categories: outcome, process, cost, and others. The vaccine effectiveness (21/53, 40%) and safety (7/53, 13%) were the most frequently reported and important attributes. Subgroup analyses showed that vaccine effectiveness was the most important attribute, although the preference varied by subgroups. Compared to high-income countries (3/29, 10%), a higher proportion of low- and middle-income countries (4/24, 17%) prioritized safety. As the pandemic progressed, the duration of protection (2/24, 8%) during the pandemic wave and COVID-19 mortality risk (5/25, 20%) after the pandemic wave emerged as 2 of the most important attributes.

Conclusions

Our review revealed the critical role of vaccine effectiveness and safety in COVID-19 vaccine preference. However, it should be noticed that preference heterogeneity was observed across subpopulations and may change over time.

Trial Registration

PROSPERO CRD42023422720; https://tinyurl.com/2etf7ny7
Language and Intercultural Communication: Belgian Business Owner with Indonesian Workers in Murianto Workshop, Jepara, Central Java
Authors: Ulfani Kireina Geza , Handayani Andri
Published: July 2024

This study explores the dynamics of intercultural communication between Niels Evens, a Belgian business owner, and his Indonesian workers in the Murianto Workshop in Jepara, Central Java. Drawing upon the Communication Accommodation Theory (CAT) by Giles and Coupland and the Conversational Constraints Theory (CCT) by Kim, the study discusses the interplay of cultural adaptation and communication strategies. The objectives of this study are to understand the implementation of CAT and CCT by the owner and the workers of Murianto Workshop in Jepara, Central Java, and also to identify the constraints during the communication between the owner and the workers of Murianto Workshop. The data for this research was gathered through a semi-structured interview conducted with Niels Evens and presented descriptively.The finding shows that Niels Evens’ effort to adapt and understand the local culture can be called convergence from the Communication Accommodation Theory. Although many of his actions reflect collectivist tendencies, he establishes boundaries with his workers to maintain a professional work environment. From the Conversational Constraints Theory, it can be concluded that the constraints faced by Niels Evens are about clarity and effectiveness concerns. The constraints he faced are related to the change of communication strategy from a direct to an indirect approach, which is also his constraint in adapting to the local culture.
The Charms of the Nature vs. Realities of People Living alongside the Water in Indonesian Poetry
Authors: Sitepu Ied Veda
Published: July 2024

In Indonesia, a country in which 70% of its area is water, people relate easily to both the sea and inland water, such as rivers and lakes. Authors consequently also find inspiration in these bodies of water, expressing their admiration towards the beauty of nature. For example, while they originate from different literary eras, “Danau Toba” (Lake Toba) by Sitor Situmorang, “Sepantun Laut” (Like the Sea) by J.E. Tatengkeng, “Akulah Si Telaga” (I am the Lake) by Sapardi Djoko Damono, “Apa Kata Bintang di Laut” (What the Star Tells the Sea) by Iwan Simatupang, “Kali Martapura” (Martapura River) by Hidjaz Yamani, and “Perempuan Pesisiran” (Women on the Coasts) by Iman Sembada all reflect the dynamic portrayals of water in Indonesian literature, as a charm of nature from each poet’s perspective or a framework for criticizing the realities of the lives of the people who live alongside water. This research analyzed these authors’ interconnectedness with nature, employing the qualitative descriptive method and using ecocriticism theory, which explores how nature is depicted in the respective poems and connects human relationships to nature. The results showed that the poets easily relate to the river, lake, or sea, and aside from describing the beauty of nature based on fond memories, their poems are used as critiques of the changing relationship between humans and nature, as well as between humans and humans. Their portrayals of nature further reveal the feelings of belonging engendered by water, which they use as criticism for the destruction of nature and societal changes stemming from the need for progress.
Research on the Transformation of Traditional Banking Business in the Context of Big Data
Authors: Hu Yue
Published: July 2024

In recent years, with the rapid development of big data, its position and value in the economic development system of the entire country are unshakable. In this situation, how to overcome the challenges and seize unprecedented opportunities has become a necessary research issue. This paper systematically discusses the current development status of big data from four aspects of big data: technology, security, application, and management, and shows the opportunities and challenges faced by traditional banks from three aspects of asset business, liability business, and intermediary business under the background of big data. It also puts forward suggestions on diversification, specialization, and digital transformation in three aspects of asset profitability, liability structure, and intermediary business innovation. Big data will have a fundamental and profound impact on the business transformation of traditional banks and provide a continuous stream of new vitality for the transformation of traditional banks.
Application of Financial Regulatory Technology (RegTech) and Its Impact on Financial Stability
Authors: Li Wenjing
Published: July 2024

Financial Regulatory Technology (RegTech), a significant branch of FinTech, leverages advanced technologies such as big data, artificial intelligence, and blockchain to enhance the efficiency and effectiveness of financial regulation. As the complexity and risk of financial markets increase, traditional compliance and risk management methods have become insufficient for modern regulatory needs. RegTech significantly improves compliance efficiency and risk management capabilities of financial institutions through automation, real-time monitoring, risk prediction, and reporting generation, while also enhancing the regulatory capacity of authorities, thereby promoting financial system stability. However, the application of RegTech also faces challenges such as technical malfunctions, data security, and regulatory lag. By analyzing successful and failed cases of RegTech, this paper explores its positive impact on financial stability and potential risks, and provides an outlook on future trends. Overall, RegTech has played a significant role in enhancing regulatory efficiency and market transparency, but further optimization is needed in terms of technical security, regulatory adaptation, and international cooperation to ensure its continued positive contribution to financial market stability.
La flexibilización probatoria en el proceso penal
Authors: Sierra Sorockinas David , Toro Taborda Mariana
Published: July 2024

This paper aims to analyze a type of epistemic injustice in the field of criminal procedural law. The central research question is: can reverse onus in criminal trial lead to epistemic injustice? To address this question, the text will be divided into three parts. First, we examine the concept of epistemic injustice and its various modalities. Second, we present the conditions under criminal trials in an epistemic setting. We characterize the criminal trial in an epistemological key. Finally, in third place, we present why a change in the institutional design (the burden of proof) leads to epistemic injustice.
Subaltern Voices Appear in Mulkraj Anand\'s Novel "UNTOUCHABLE"
Authors: Ramteke Dr. Damodhar G.
Published: July 2024

Abstract: The Dalit and subaltern class of Dr. Mulk Raj Anand's time in India are portrayed realistically and sympathetically in his novels, which focus on the class's struggle to make ends meet and the ways in which the upper class and well-to-do people in society exploit and deny them any opportunities. Anand is a famous English-language critic of the Indian literary scene. Anand is a prolific writer who writes in both English and Hindi. His works include novels, short tales, and articles on the arts. Anand was among those who translated Hindustani idioms into English. His picture of India's poor is so spot-on that it's hard not to feel compassion for them. Anand is the first Indian novelist to write in English, and his works show the genuine hardships of the oppressed Indian people. Anand became as a leader in advocating for marginalized groups. Many of his most popular characters come from marginalized communities. Anand's made-up world is populated mostly by down-and-outers like janitors, coolies, farmers, and factory employees. The current study will use an inquiring, interpreting, evaluating, and analyzing research strategy. Mulk Raj Anand, a novelist who is deeply committed to social justice, has penned several works on the subject. More than a dozen books, seventy short stories, and several essays and articles have been published under his name. Input from both primary and secondary sources has been compiled. Mulk Raj Anand, a social pundit, talks about the shortcomings of capitalism. Mulk Raj Anand, the author we've picked, presents the tale of colonial India from the perspective of the country's lowest strata. Mulk Raj Anand is an esteemed writer whose works have greatly influenced the development of Indian literature in English. Simply said, Anand is the only published author who has ever addressed the plight of the homeless and the social pariah. A voice that is forceful and powerful yet muffled by the stifling fabric of tradition and convention runs throughout Anand's work like a constant undercurrent.
O uso inadequado do conhecimento científico nas mensagens falsas sobre a pandemia de covid-19
Authors: Queiroz Lucas Dias , Lima Guilherme da Silva
Published: July 2024

Diversas mensagens falsas circularam durante a pandemia de covid-19, muitas delas foram compostas por elementos científicos e tecnológicos. O objetivo deste trabalho é analisar como a incorporação de aspectos científicos e tecnológicos foram usados em mensagens falsas sobre a pandemia. A partir do banco de dados disponibilizado pela Latam Chequea Coronavírus, selecionamos 152 mensagens falsas que apresentaram o uso inadequado do conhecimento científico. Os resultados apontaram que as mensagens falsas se apropriaram da ciência e da tecnologia, visando usurpar seu valor social em busca de credibilidade. Para isso, as mensagens falsas usaram recursos verbo-visuais, autoridades e misturam informações verdadeiras e falsas.
KOMPETENSI SOFT SKILL KEPEMIMPINAN LEMBAGA PENJAMINAN MUTU UIN AR-RANIRY DALAM PENGEMBANGAN KREATIVITAS SUMBER DAYA MANUSIA
Authors: Oktana Indah , Husna Nadiatul , Marsithah Iis , Mutia Sri
Published: July 2024

AbstrakPenelitian ini bertujuan untuk menganalisis kompetensi kepemimpinan LPM UIN Ar-Raniry dalam pengembangan sumber daya manusia. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif, data dikumpulkan melalui observasi partisipan, dokumentasi dan wawancara mendalam, analisis data dilakukan dengan model tematik. Hasil penelitian mengungkapkan bahwa proses pengembangan sumber daya manusia dalam lingkungan LPM UIN Ar-Raniry dilakukan melalui tahapan pelatihan dan Pendidikan. Kompetensinya adalah memiliki gaya komunikasi yang efektif, serta memiliki kompetensi soft skill meliputi kemampuan berkomunikasi, memiliki hubungan yang baik, memberi motivasi, mampu memecahkan masalah. Inisiatif, kerja sama tim dan pemberdayaan. Dan kompetensi hard skil terdiri: teknologi computer dan analisis data serta kreativitas SDM dalam bekerja. Dua kompetensi tersebut digunakan oleh kepala LPM dalam mengembangkan SDM meliputi: pelatihan dan pendidikan
Strategi Kepala Madrasah Dalam Pengelolaan Konflik di MAN 3 Banda Aceh
Authors: Dhin Cut Nya , Bararah Isna Wardatul , Daulay Namiah , Raudhaturrahimah Raudhaturrahimah
Published: July 2024

Conflict is a problem that can occur in various organization/institutions, including madrasah. In dealing with conflict between teachers when selecting teachers to serve in the school organizational structure, madrasah principals have several methods for resolving conflicts so that they do not have a negative impact on the school environment. The aims the of this research are 1) to find out the methods of madrasah heads in resolving conflicts at MAN 3 Banda Aceh 2) To find out the obstacles faced by madrasah heads in resolving conflicts at MAN 3 Banda Aceh. The type of research carried out is qualitative, with data collection techniques namely observation, interviews and documentation. The subjects in this research consisted of 3 informants, namely the head of the madrasah, the deputy head of the madrasah for curriculum and 1 homeroom teacher for class X MIA 3. The results of this research show that 1) the method used by the madrasah head to resolve conflicts related to the system for selecting members of the organizational structure is to use 4 methods, namely the method of stimulating conflict, the method of reducing conflict, the method of managing conflict, and the method of conciliation. 2) The obstacles that madrasah heads face in resolving conflicts are misunderstandings and lack of understanding of the rules that occur within the parties involvet in the conflict, resulting in differences of opinion. With the methods used by madrasah heads in resolving conflicts, these problems can be resolved well even though they are not free from obstacles.
Urban interethnic community through the lens of state national policy
Authors: Popkov Yuriy V. ,   Institute of Philosophy and Law, Siberian Branch of the Russian Academy of Sciences
Published: July 2024

Relying on the theoretical and empirical developments of representatives of the Novosibirsk scientific ethnosociological school on ethnosocial issues, the author updates and develops them in the aspect of the special emphasis of the state national policy on cities. In existing doctrinal documents, which have serious conceptual limitations and gaps on basic issues, there is no such emphasis, although it is cities today that set the dominant trends in the ethnosocial dynamics of society and at the same time concentrate the most pressing problems in the sphere of interethnic relations and national politics. The necessity of developing and implementing in practice an effective integration national policy at different levels of social organization, including its regional and local scale, is substantiated. The implementation of this task is associated with considering the city as an interethnic community, which develops in the course of localised ethnosocial processes and which is proposed to be perceived as a complex object of national policy at the municipal level. In contrast to the term “multi-ethnic community”, which is common in the West, the concept of “inter-ethnic community”, according to the author, reflects not only the presence of a certain set of ethnically marked subjects and the difference in their positions in a specific socio-cultural space, but also a certain level of their interdependence and integration. The contradictory patterns of city functioning under the influence of migration processes, which have projections into modern times, are highlighted. The features of the Concept of sustainable ethno-social development of the multinational community of the city of Novosibirsk, which was developed with the participation of the author and adopted as a regulatory document for the implementation of state ethnic policy in the largest municipal formation in Russia, are recorded. It is concluded that in order to create an effective mechanism for managing the ethnosocial development of the urban interethnic community, as well as municipalities in general, it is necessary to expand the powers of local authorities and create real institutional, legal, administrative, financial and personnel capabilities.
What do they say in mosques of Tashkent? Discourse of the Muslim clergy on the limitation of ritual costs
Authors: Ashirov Adhamjon A. ,   Institute of History, Academy of Sciences of the Republic of Uzbekistan
Published: July 2024

The article analyses the changes that occurred during the period of independence of Uzbekistan in the religious life and national values of the population of the capital of the republic – the city of Tashkent, which are associated with family rituals. Based on field data, the author reveals a combination of religious and national aspects in Uzbek family rituals regarding the wedding ritual. The article analyses the views of imams concerning the costs and excesses of its implementation. Through observations of modern Uzbek society, Muslims’ social activities, the analysis of the Muslim clergy sermons at Friday prayers, their work on websites, social networks and instant messengers, the author draws attention to the breadth of discussions by Uzbek imams on family and marriage issues. The influence of the constant efforts of the Muslim clergy on changes in the volume of expenses spent on the ritual life of the Uzbek people is emphasized. It is particularly noticeable in wedding ceremonies. The work reveals transformations in Uzbek family rituals from the point of view of ritual economy.
IT Job Preference Categorization
Authors: Khlobystova A. O. , Abramov M. V. , Tulupyeva T. V.
Published: July 2024

The aim of the study is to develop a questionnaire integrating traditional career guidance techniques and categorization of IT professions by analyzing existing classifications and interviewing IT specialists. Methods. In order to achieve the objective, we selected a traditional career guidance methodology by analysing the existing ones and selecting the one that best corresponds to the research objective; we also selected a system of categorisation of IT specialties by analysing the existing classifications and interviewing IT specialists. Results. Among the existing traditional career guidance techniques, the Holland Test was selected as having the potential to be adapted to the IT field. The analysis of the existing classifications of IT specialities showed the lack of unity, in this context our own categorisation was developed, including five main categories: development, QA specialists, working with data and research, management, design. Conclusions. Based on the results of the study, it was hypothesised that there are differences in the degree of expression of the Holland types among the different IT professions. Also, the presumed correspondence between different categories of IT professions and the predominant Holland types is given. The study forms the basis for the development of a software product that will help people to identify the most suitable IT professions for them.
Sociological Conceptualization of the Concept of “Driver” in the Context of Solving Problems of Development of Socio-Humanitarian Research at Russian Universities
Authors: Kashina M. A. , Vasilyeva V. A. , Tkach S.
Published: July 2024

These days, management studies and domestic economic and sociological research frequently employ the term “driver.” Additionally, this concept’s cognitive capacity is significantly reduced by the lack of an agreed-upon definition. The article’s purpose is to demonstrate the concept of “drivers” heuristic potential for sociological analysis of issues related to the growth of sociohumanitarian research in Russian universities. Three components of the university’s social structure—academic ethics compliance, graduate school, and online academic communities— are regarded as internal drivers of socio-humanitarian research in Russian universities after firstconceptualizing the term “driver” from the standpoint of sociological theory. Study design. This is a pilot project that uses secondary data analysis as its foundation. The information theory developed by K. Shannon provides the theoretical framework that enables us to identify the characteristics of the driver that set it apart from other system mediating components. The frameworks of institutional analysis and the theory of social action are used in the process of sociological conceptualization. This enables us to draw attention to the social system’s motivator’s subjective element. Results. A general definition of the concept of a driver is given, and two of its key attributes — its requirement and information recoding — are emphasized. It is demonstrated that the sociological reading of the driver is linked to an evaluation of the degree of functionality of the effects of its operation on the social structure. The personal qualities of the individuals involved in its work define the nature of these consequences. In this sense, the driver can influence the social system’s growth as well as its stagnation. University research can be internally motivated by a variety of factors, such as upholding academic ethics standards, successfully implementing postgraduate programs, and founding and moderating online academic communities. The novelty of the results obtained is associated with the implementation of technical terms into socio-humanitarian knowledge, which made it possible to give a more rigorous definition of the concept of driver in relation to the analysis of social changes and processes. The article will be of interest to science administrators at universities.
Hubungan Antara Panjang Tungkai dan Daya Ledak Otot Tungkai Terhadap Kecepatan Lari 50 Meter
Authors: Kurniawan Alexander , Haryanto Deri , Sukendro Sukendro
Published: July 2024

Tujuan penelitian ini yaitu untuk mengetahui hubungan panjang tungkai dan daya ledak otot tungkai terhadap kecepatan lari 50 meter pada siswa putra SMP Negeri 2 Kerinci. Penelitian ini menggunakan metode korelasi, dalam penelitian ini penelitian ini adalah penelitian korelasional dengan pengambilan datanya dilakukan dengan tes dan pengukuran, dalam metode ini peneliti berusaha menggambarkan dengan sejelas-jelasnya mengenai panjang tungkai dan daya ledak otot tungkai dengan prestasi lari 50 Meter. Sampel dilakukan ditujukan kepada siswa putra yang berjumlah 45 orang secara total sampel. Berdasarkan analisis data yang diperoleh variabel X1 terhadap Y mudah dilihat bahwa t hitung 12,9749  >  t tabel 1,6811 maka terdapat hubungan antara panjang tungkai dengan kecepatan lari 50 meter. Variabel X2 terhadap Y dilihat bahwa t hitung 5,266207  > t tabel 1,6811 maka terdapat hubungan antara  daya ledak otot tungkai dengan kecepatan lari 50 meter. Untuk variabel X1 dan X2 Terhadap Y diketahui r hitung = 0,893574. Kemudian data tersebut diuji signifikansi korelasi dengan dibandingkan rtabel pada taraf signifikansi 5% = 0,294 yang berarti r hitung  > r tabel. Dengan demikian dapat disimpulkan terdapat  hubungan antara panjang tungkai dan daya ledak otot tungkai terhadap kecepatan lari 50 meter pada siswa putra SMP Negeri 2 Kerinci
Efektivitas Project Based Learning dalam Kurikulum Merdeka terhadap Kemampuan Teknik Dasar Lempar Lembing Pada Mahasiswa
Authors: Yuliawan Ely , Arsil Arsil
Published: July 2024

Penelitian ini memiliki tujuan mengetahui keefektifan model project based learning dalam kurikulum merdeka terhadap kemampuan teknik dasar lempar lembing pada mahasiswa kepelatihan olahraga Universitas Jambi. Metode penelitian menggunakan pendekatan deskriptif kuantitatif dengan metode eksperimen dan model penelitian pre-test-post-test pada kelompok (kelas) yang berjumlah 26 mahasiswa. Peneliti menemukan hasil:1) Ada perbedaan keterampilan teknik dasar lempar lembing mahasiswa sebelum dan setelah diterapkannya model belajar berbasis proyek, 2) Penggunaan model belajar berbasis proyek berpengaruh signifikan terhadap teknik dasar lempar lembing pada mahasiswa kepelatihan olahraga, dan 3) Penggunaan perlakuan dengan model pembelajaran berbasis proyek efektif pada keterampilan teknik dasar lempar lembing dan berada pada kategori baik
Analisis Kebutuhan Pengembangan Modul Elektronik Matematika Berbasis Discovery Learning
Authors: Efendi Rendi Nur , Nugraha Ugi
Published: July 2024

Penelitian ini bertujuan untuk memastikan apakah siswa kelas V sekolah dasar memerlukan modul elektronik matematika berbasis Discovery Learning yang berfokus pada kubus dan balok. Permasalahan yang dihadapi adalah kurangnya bahan ajar yang terintegrasi dengan pendekatan Discovery Learning, yang dapat mempengaruhi minat dan pemahaman siswa dalam belajar matematika. Metode penelitian yang digunakan adalah kualitatif, dengan pendekatan pengumpulan data melalui wawancara dengan pengajar kelas V dan penyebaran kuesioner kepada guru serta siswa. Tujuan dari penelitian ini adalah untuk menganalisis kebutuhan pengembangan modul matematika elektronik berbasis kubus dan balok di kelas V Sekolah Dasar menggunakan Discovery Learning. Partisipan dalam penelitian ini adalah siswa kelas V A SD Negeri 66/IV Kota Jambi dan wali kelas VA. Teknik pengumpulan data meliputi analisis kurikulum, analisis karakter siswa, dan analisis kondisi lapangan. Hasil penelitian menunjukkan bahwa siswa kelas V SD membutuhkan sumber ajar berupa modul matematika elektronik berbasis Discovery Learning pada kubus dan balok. Berdasarkan temuan tersebut, disimpulkan bahwa perlu dikembangkan bahan ajar berupa modul elektronik sebagai alternatif bahan ajar berbasis Discovery Learning karena bahan ajar yang digunakan guru saat ini belum terintegrasi dengan pendekatan tersebut. Pengembangan modul ini diharapkan dapat membangkitkan minat dan semangat siswa untuk belajar matematika, serta meningkatkan pemahaman mereka terhadap konsep kubus dan balok. Saran dari penelitian ini adalah agar guru mulai mengadopsi dan mengintegrasikan bahan ajar berbasis Discovery Learning dalam proses pembelajaran untuk mendukung perkembangan intelektual dan keterampilan problem-solving siswa.
Kata Kunci: Modul Elektronik, Discovery Learning, Matematika
Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study
Authors: Chung Jae-Wook , Park Seo Young , Woo Seunghee , Kim Yun Ah , Kang Jun-Koo , Ha Yun-Sok , Lee Jun Nyung , Kim Bum Soo , Kim Tae-Hwan , Yoon Ghil Suk , Kwon Tae Gyun , Kim See Hyung
Published: July 2024

Purpose: We prospectively compared the diagnostic accuracy of kidney dynamic computed tomography (KDCT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasonography (CEUS) for the assessment of small renal mass (SRM) (≤4 cm).Materials and Methods: Seventy-six patients with SRM (mean age, 58.4±13.1 years) who underwent renal biopsy (n=11) or nephrectomy (partial or radical) (n=65) were enrolled. All patients underwent KDCT, MRI, and CEUS before renal biopsy or nephrectomy.Results: The mean maximal tumor size was 21.0±9.8 mm. The mean R.E.N.A.L nephrometry score was 7.0±1.7. Fifty-six patients had renal cell carcinoma (RCC) (clear cell, 42; papillary, 7; chromophobe, 5; succinate dehydrogenase deficient, 1; unspecified RCC, 1). Twenty patients had a benign tumor (angiomyolipoma, 11; oncocytoma, 3; others, 6). Clinicopathologic variables were comparable in RCC and benign groups. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of KDCT were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of MRI were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of CEUS were 85.7%, 50.0%, 82.8%, and 55.6%, respectively. The diagnostic accuracy of KDCT, MRI, and CEUS were 68.4%, 68.4%, and 76.3%, respectively. In a subgroup analysis based on clinical tumor size of 10 mm and 20 mm, CEUS also showed the highest diagnostic accuracy.Conclusions: CEUS had the highest specificity, PPV, and NPV and may help improve the assessment of SRM.
Comparison of Outcomes Between Radical Nephrectomy and Partial Nephrectomy in Clinical T2 Renal Cell Carcinoma: A Retrospective Korean Renal Cell Carcinoma Cohort Study
Authors: Chung Younsoo , Byun Seok-Soo , Hong Sung Kyu , Lee Sangchul , Jeong Chang Wook , Kang Seok Ho , Hong Sung-Hoo , Lee Ji Youl , Kim Yong-June , Chung Jinsoo , Hwang Eu Chang , Kwon Tae Gyun , Kim Jung Kwon
Published: July 2024

Purpose: We compared the surgical outcomes of radical nephrectomy (RN) and partial nephrectomy (PN) in adult patients with clinical T2 stage (cT2) renal cell carcinoma (RCC) by utilizing data from the Korean Renal Cell Carcinoma (KORCC) database.Materials and Methods: We retrospectively analyzed adult patients with cT2 RCC from 8 tertiary hospitals who were registered in the KORCC between 2003 and 2023. Patients with a solitary kidney or bilateral tumors were excluded. The patient cohort was divided into RN and PN arms, and propensity score matching (PSM) was conducted with a 1:3 ratio. Perioperative and survival outcomes were compared between arms.Results: After PSM, the PN and RN arms included 44 and 132 patients, respectively. No significant differences were observed in baseline characteristics, apart from laterality, following PSM. Regarding perioperative outcomes, complications of Clavien-Dindo classification grade III or higher (11.4%, p<0.001) and urological complications (9.1%, p=0.045) were more common in the PN arm than in the RN arm. Postoperative renal function was superior in the PN arm, whereas the incidence of de novo chronic kidney disease (CKD) at 6 months was higher among the recipients of RN (37.6%, p<0.001). Pathological examination indicated a higher pathological T stage in the RN arm. Overall, cancer-specific, and recurrence-free survival rates did not differ significantly between arms. Based on Cox regression analysis, the use of PN was not a significant predictor of recurrence-free survival (hazard ratio, 0.675; p=0.474).Conclusions: In cT2 RCC, PN was associated with a lower incidence of de novo CKD than RN. No significant differences in survival outcomes were noted. PN may represent a viable alternative to RN for certain patients with cT2 RCC. Further research is warranted to explore the management of advanced RCC.
Robot-Assisted Radical Nephrectomy With Inferior Vena Cava Thrombectomy: A Narrative Review With Step-by-Step Procedures
Authors: Bang Seokhwan , Hong Sung-Hoo
Published: July 2024

Inferior vena cava (IVC) thrombi are detected in 4%–10% of patients with renal cell carcinoma (RCC). The 5-year survival rates following radical nephrectomy (RN) with IVC thrombectomy for patients with nonmetastatic RCC range between 50%–65%. Despite robot-assisted RN (RARN) with IVC thrombectomy proving to be feasible and potentially lessening complication rates, it remains technically demanding, with significant associated morbidity and mortality risks. Thus, meticulous patient selection and careful surgical planning are of paramount importance. This review aims to encapsulate the latest advancements and outline the detailed surgical processes involved in RARN with IVC thrombectomy.
The Role of Fibroblast Growth Factor Receptors Inhibitors in Bladder Cancer
Authors: Seo Ho Kyung , Jung Eui Hyun , Yang Sora , Lee Hye Won
Published: July 2024

Dysregulation of fibroblast growth factor (FGF)-receptor (FGFR) signaling, which is implicated in various oncogenic processes, including tumor proliferation, survival, migration, invasion, and angiogenesis, has been identified as a critical factor in urothelial bladder cancer (UBC) progression. This has led to the development of novel FGFR-targeted therapies. Erdafitinib is an oral selective pan-FGFR tyrosine kinase inhibitor approved for locally advanced or metastatic urothelial cancer in patients with FGFR3 alterations who progress on both platinum-based chemotherapy and immunotherapy. The approval of FGFR inhibitors (FGFRis), such as erdafitinib, and ongoing research into combination therapies with immune checkpoint inhibitors (ICIs) signify a promising shift in the treatment paradigm for advanced/metastatic UBC despite challenges such as the variable efficacy of FGFRis and treatment-related toxicity. In this study, we review the FGFR signaling pathway and the impact of altered FGFR signaling on UBC tumorigenesis, the clinical development of FGFRis, the rationale for FGFRi-ICI combinations, and future directions.
A Narrative Review on Systemic Therapy for Renal Cell Carcinoma in the Perioperative Setting
Authors: Tachibana Isamu , Qin Qian , Taylor Jacob , Issa Wadih , Cadeddu Jeffrey , Margulis Vitaly , Zhang Tian
Published: July 2024

In patients with renal cell carcinoma (RCC), the use of immunotherapy (IO) and tyrosine kinase inhibitor (TKI) regimens has proven beneficial in treating metastatic disease. These advances have led to the evaluation of IO/IO and IO/TKI treatment combinations in the perioperative setting. Neoadjuvant systemic therapy can improve surgical outcomes for patients by shrinking the tumor and prior studies have shown that the use of TKI regimens reduced tumor size significantly, whereas IO monotherapy had less of an objective radiographic response. In a retrospective series, patients with locally advanced RCC treated with IO/TKI experienced a higher decrease in median tumor size than those treated with IO/IO. For patients with locally advanced bulky tumors or tumor thrombus involving renal vein or inferior vena cava, early systemic treatment may be beneficial (with several trials ongoing). Finally, pembrolizumab has also improved outcomes in the adjuvant RCC setting. These studies have opened the door to other perioperative studies. Using perioperative therapies can alter the course of RCC with neoadjuvant therapies (IO/TKI) facilitating surgical challenges and adjuvant therapy (IO) improving disease-free survival, but trials are in the process and will further evaluate the impact of these treatments. In the meantime, these systemic therapies can be discussed with patients for perioperative treatment of locally advanced and invasive RCCs.
Autocitação na Ciência da Informação no Brasil estudo bibliométrico com pesquisadores PQ1 (2004-2021)
Authors: Silva Jéssyca Maria Santos da , Rosas Fábio Sampaio , Grácio Maria Cláudia Cabrini
Published: July 2024

Analisa o comportamento de autocitação dos pesquisadores bolsistas de Produtividade em Pesquisa nível 1 da área da Ciência da Informação. Avalia diacronicamente a intensidade das autocitações nos artigos publicados de 2004 a 2021, por sexsênio e categoria. Como resultado observou-se que os pesquisadores tiveram porcentagem de autocitação abaixo do valor apontado como limite para uma potencial evidência de má conduta ética. A média de autocitação foi crescente por categoria: categoria A com a maior média de autocitação e a categoria D a menor média neste indicador.
Caminhos acadêmicos uma abordagem de redes para compreender as conexões institucionais
Authors: Mascarenhas Higor Alexandre Duarte , Dias Thiago Magela Rodrigues , Mascarenhas Letícia Duarte
Published: July 2024

A crescente migração de brasileiros em busca de melhores condições de vida motiva este estudo. Investigou-se o êxodo de estudantes brasileiros durante sua formação acadêmica, analisando dados extraídos da Plataforma Lattes com técnicas de análise de redes. Utilizando o LattesDataXplorer, focou-se em doutores, devido ao alto nível de formação e constante atualização de seus currículos. A análise baseada em redes revelou padrões, destacando a Universidade de São Paulo como um ponto de imigração proeminente, e possíveis colaborações institucionais.
Análise das bibliografias contidas em planos de ensino de disciplinas sobre estudos métricos da informação no Brasil
Authors: Nascimento Rosiane Pedro do , Vogel Michely Jabala Mamede
Published: July 2024

Pesquisa sobre bibliografias em planos de ensino de disciplinas sobre estudos métricos da informação. Objetivo é verificar quais referências são usadas como fonte de pesquisa pelos alunos e suporte bibliográfico pelos professores. Metodologia, identificação do corpus da pesquisa, composta por 26 planos de ensino. Resultados: a autora mais citada foi Maria Hayashi, e o com mais publicações foi Adilson Pinto, o livro mais citado: Bibliometria: teoria e prática. Elementos mais citados: artigo científico, o idioma português, as décadas de 2000 e 2010 e o periódico Ciência da informação. Resultados mostram que a bibliografia citada aborda perspectivas tradicionais dos estudos métricos.
Alinhamento da produção científica da Universidade Federal de Pernambuco com a Agenda 2030 da ONU um olhar sobre os Objetivos do Desenvolvimento Sustentável
Authors: Corrêa Dominique de Lira Vieira , Silva Fábio Mascarenhas e , Freitas Juliana Lazzarotto , Correia Anna Elizabeth Galvão Coutinho
Published: July 2024

Relaciona a produção científica da Universidade Federal de Pernambuco aos Objetivos do Desenvolvimento Sustentável da ONU. Adota a análise cientométrica de um corpus de publicações da plataforma Scopus, utilizando a Base SciVal como recurso de análise no período selecionado, 2013 a 2022. Os resultados demonstram que houve maior representação, na produção analisada, dos objetivos relacionados com as questões ambientais e de saúde, enquanto os ligados à igualdade social e de gênero, fome e educação incidiem de forma menos expressiva. O estudo permite melhor compreender os esforços locais de desenvolvimento sustentável da comunidade da UFPE, e as lacunas e necessidades não atendidas
Al-Awbi'at fi al-Turats al-Islami: al-Tashkhis wa al-Waqaya wa al-'Ilaj
Authors: Benaired Hadj
Published: July 2024

The Islamic world, like other nations, has faced numerous pandemics throughout history, profoundly shaping its societal landscape. Muslims historically addressed such challenges in accordance with the teachings of Prophet Muhammad (peace be upon him), employing both spiritual practices, such as supplication and purification rituals, as well as practical measures. Among the most devastating pandemics was the Black Plague in the mid-8th century, which ravaged the Islamic world and beyond, spanning Asia and Europe. This pandemic reshaped demographics and left a lasting impact on states and societies. Islamic scholars and physicians played pivotal roles during this crisis, documenting its effects, proposing solutions, and contributing to medical advancements. This research aims to explore the contributions of Muslim scholars and doctors in combating the Black Plague, documenting their writings, proposals, and medical interventions. By examining their efforts, we gain insights into historical approaches to pandemics and strategies for prevention and treatment.
The Islamic Perspective on Political Asylum: Analysis of The Rohingya Refugee Issue in Aceh, Indonesia
Authors: Makkarateng Ma'adul Yaqien , Arake Lukman
Published: July 2024

This article discusses the issue of Rohingya refugees in Aceh, Indonesia, from an Islamic perspective. The Rohingya refugees flee from violence and discrimination in Myanmar, seeking asylum in neighboring countries, including Indonesia. This research employs a qualitative method to gather and analyze data to understand the concepts, opinions, and experiences related to this issue. The findings indicate that Islam emphasizes the importance of humanity, even towards non-Muslims. The majority of Acehnese people oppose the Rohingya refugees due to concerns over economic security and social cohesion. However, they do not justify the violation of human dignity and rights. Islam teaches tolerance, justice, and kindness to all of God's creatures. Despite the challenges in handling refugees, support and cooperation from the government and the international community are crucial in seeking comprehensive long-term solutions to the Rohingya crisis. This article also examines political asylum policies from the perspective of Islamic law, emphasizing that Islam is a religion that acknowledges and respects human rights, encouraging its followers to be just and kind to all people, including non-Muslims.
Hands-on activity to facilitate the teaching – learning process of discrete simulation topics
Authors: Zuluaga Carlos Mauricio , Gómez Suta Manuela del Pilar
Published: July 2024

This article presents a proposal of a hands-on activity to facilitate the teaching - learning process in thematic and computational instruments associated with Discrete Simulation. At first, the theoretical support of the pedagogical methodology used for its design is presented and basic notions of the themes that can be explored in the hands-on activity are presented. Subsequently it presents the development of the proposal and the resulting simulation model, which can be achieved by executing the pedagogical environment exposed. Finally, some conclusions and considerations are developed.
Modelo sistema de gestión de seguridad de la información para instituciones educativas de nivel básico
Authors: Blandón Jaramillo Carlos Arturo , Benavides Sepúlveda Alejandra María
Published: July 2024

El Ministerio de Tecnologías de la Información y las Comunicación – MINTIC ha establecido directrices que permiten implementar sistemas de gestión de seguridad de la información – SGSI en las entidades del estado. La educación pública es un servicio y un derecho de los niños y niñas consagrado en la Constitución Política de Colombia, circunscrito en el Decreto Reglamentario 1078/2015, que contiene a su vez lo lineamientos para la implementación de la estrategia de gobierno en línea – GEL, incluyendo un SGSI basado en la norma NTC ISO/IEC 27001. El proyecto consiste en realizar un análisis de riesgos con base en la norma ISO 27005 identificando los activos críticos del área de secretaría académica de las instituciones educativas – IED’s de nivel básico y los riesgos asociados, para generar un plan de tratamiento de riesgos que permita proponer una declaración de aplicabilidad, así mismo analizar la normatividad del Ministerio de Educación, del MINTIC y los requisitos de la norma NTC ISO/IEC 27001 que permitan proponer un modelo general que facilite la implementación de un SGSI en este tipo de instituciones. El modelo resultante cumple con los requisitos obligatorios establecidos en la norma NTC ISO/IEC 27001, y constituye una base para garantizar la disponibilidad, integridad y confidencialidad de la información sensible de los niños, cumpliendo las disposiciones pertinentes del sector educación, sector TIC componente seguridad y privacidad de lainformación.
Programación por demostración del agarre de objetos empleando técnicas basadas en modelo de mezcla de Gausianas
Authors: Hoyos Gutierrez Jose Gabriel , Navarro Pérez Alvaro Andrés
Published: July 2024

Se presenta una técnica que permite agarrar un objeto empleando la combinación de técnicas de programación por demostración. Las técnicas son el modelo de mezcla de gaussianas parametrizado en la tarea y el modelo de mezcla de gaussianas. Con la primera se estima la trayectoria de la mano para una nueva posición y orientación del objeto, el valor final obtenido de posición y orientación no siempre es exacto, por lo que se aplica un segundo paso o paso de corrección empleando el modelo de mezcla de gaussianas. A través de un experimento real se obtiene una base de datos de demostraciones de agarres y   se prueba el algoritmo propuesto. Luego empleando evaluación subjetiva de la calidad del agarre y gráficas del error se muestra que la técnica presentada mejora la respuesta lograda al solo emplear el modelo de mezcla de gaussianas parametrizado en la tarea.
Caracterización experimental de paneles compuestos elaborados con fibras de Arundo Dónax y resina vegetal
Authors: Sánchez Cruz Martha Lissette , Baquero Bastos David Esteban , Monsalve Alarcón Jonathan
Published: July 2024

Paneles compuestos fueron elaborados con fibras de Arundo Dónax aleatoriamente distribuidas en una resina vegetal. Las fibras fueron extraídas por vía mecánica. Para La elaboración de los paneles fue utilizado un método de moldeo manual y compactación por prensado. La determinación de las propiedades físicas se enfocó en la evaluación de la capacidad de absorción, la densidad y el porcentaje de hinchamiento. Para evaluar el desempeño mecánico se realizaron ensayos de resistencia a tensión, compresión y flexión. La influencia del porcentaje de fibras en el comportamiento del material fue analizada. Los resultados fueron comparados con resultados disponibles en la literatura para paneles comerciales.