bluuebunny/crossref_metadata_2025 huggingface dataset:
Drug Resistance Mechanism among Acinetobacter Species
Authors: Jayashree S. , Rajeshwari K.G. , Wadekar Mita D.
Published: June 2021

Acinetobacter species cause infections that are difficult to control due to multi-drug resistance and are noted for their intrinsic resistance to antibiotics and for their ability to acquire genes encoding resistance for the production of beta-lactamases and Aminoglycoside-modifying enzymes. MBLs are molecular class B and functional group 3 beta-lactamases which have the capability of hydrolyzing all β-lactams except the Monobactam, Aztreonam. Of several MBLs, only IMP, VIM and SIM types have been detected in these species. To analyze the antibiotic resistance patterns among Acinetobacter isolates and to detect Carbapenemase and MBL among MDR Acinetobacter isolates. The descriptive study of all phenotypically identified strains and multidrug-resistant strains of Acinetobacter species was conducted. A total of 303 isolates were isolated from various samples. They were processed and identified by standard Microbiological procedures. The antibiotics susceptibility testing was performed by Kirby- Bauer disc diffusion method using CLSI guidelines. Carbapenemase production was detected by employing 3 phenotypic test methods (MHT, CDM and DDST). Of 6355 samples processed, 303 were found to be Acinetobacter species, among those 50 were multidrug-resistant strains. The highest isolation of MDR Acinetobacter was from endotracheal tube tip (42%) and pus sample (32%). The majority of MDR Acinetobacter infection was found in male patients 36 (72%) compared to female patients 14 (28%). The majority of the strains were isolated from patients >/ 60 years of age group (%). A number of these isolates were more from ICU wards (30%) followed by Surgery wards (24%). Higher resistance for the Piperacillin/tazobactam ((82%), followed by Ceftazidime (80%), Imipenem (76%) etc. and the most susceptible drug was found to be the Tigecycline (82%) followed by Colistin (80%). Carbapenemase production was detected by MHT and 24 (48%) isolates were MHT positive. MBL production was detected by CDM and 34 (68%) isolates were CDM positive and by DDST 30 (60%) isolates were positive. Acinetobacter species are increasingly important nosocomial pathogens and are capable of rapid adaptation to the hospital environment. The variety of potential source of contamination or infection with these species in the hospital environment makes control of outbreaks caused by these difficult.
Human Coronavirus: Envelope Protein Evolution
Authors: Ankulkar Rutuja
Published: June 2021

Envelope protein of human coronavirus play significant role in an evolution and mutation of the virus life cycle. In the present research, the author evaluated amino acid sequences, its abundance and GC content of the genes that corresponds to envelope proteins’ of the human coronaviruses, identified from year 2003-2019. It includes SARS-CoV (2003), HCoV-NL-63 (2003), HCoV-HKU-1 (2004), MERS-CoV (2013), and SARS-CoV-2 (2019). The present research findings illustrated a point mutation in D2 location of SARS-CoV-2 (2019), representing Arginine in the place of Glutamic acid (SARS-CoV, 2003) where glycine was found deleted. SARS-CoV-2 (2019) coronavirus revealed increased abundance of Glutamic acid (100%), Asparagine (67%), Serine (300%) and Valine (85.7%) in comparison with HCoV-NL-63 (2003). We observed lower GC content in the SARS-CoV-2 (2019) among SARS-CoV (2003) and MERS-CoV (2013). The present findings have evolutionary significance and indicate SARS-CoV-2 (2019) adaptation in human.
PERBANDINGAN HUKUM ARBITRASE DAN ALTERNATIF PENYELESAIAN SENGKETA ARBITRASE ONLINE INDONESIA DAN CINA
Authors: Wibowo Afrizal Mukti
Published: June 2021

This article focuses on legal comparisons between Indonesian law and China law regarding arbitration and alternative dispute resolution, especially online arbitration. The author sees a similarity in terms of law, namely that there is no single law regulating the use of online arbitration. Even more, the conditions of the Covid-19 pandemic focused alternative dispute resolution to be carried out online as well. This paper is normative legal research with a comparative approach. The results of this paper are neither in Indonesia nor China regulates online arbitration in their legal system, but both provide opportunities for online arbitration to be held. There are differences in Indonesia and China. In Covid-19 pandemic situation force BANI Arbitration Center implemented online arbitration. But in China, China International Economic and Trade Arbitration Commission (CIETAC) fully implement online arbitration before covid-19 pandemic.
A Threshold for Quantum Advantage in Derivative Pricing
Authors: Chakrabarti Shouvanik , Krishnakumar Rajiv , Mazzola Guglielmo , Stamatopoulos Nikitas , Woerner Stefan , Zeng William J.
Published: June 2021

We give an upper bound on the resources required for valuable quantum advantage in pricing derivatives. To do so, we give the first complete resource estimates for useful quantum derivative pricing, using autocallable and Target Accrual Redemption Forward (TARF) derivatives as benchmark use cases. We uncover blocking challenges in known approaches and introduce a new method for quantum derivative pricing – there-parameterization method– that avoids them. This method combines pre-trained variational circuits with fault-tolerant quantum computing to dramatically reduce resource requirements. We find that the benchmark use cases we examine require 8k logical qubits and a T-depth of 54 million. We estimate that quantum advantage would require executing this program at the order of a second. While the resource requirements given here are out of reach of current systems, we hope they will provide a roadmap for further improvements in algorithms, implementations, and planned hardware architectures.
Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy
Authors: Barkalova E. V. , Pirogov S. S. , Andreev D. N. , Ovsepyan M. A. , Maev I. V. , Kaprin A. D.
Published: June 2021

Aim. A clinical description of gastroesophageal reflux disease (GERD) complicated by Barrett’s oesophagus (BO) at inadequate antisecretory therapy and the assessment of functional tests in control of conservative treatment.

Key points. A 63-yo patient with no complaints in a proton pump inhibitor (PPI) therapy was admitted for a follow-up examination for BO-complicated GERD using oesophagogastroduodenoscopy (OGDS) with biopsy, high-resolution oesophageal manometry and 24-h pH-impedance. Endoscopy revealed signs of BO (long segment C1M3), erosive reflux oesophagitis (grade B in Los Angeles classification). Non-contractile oesophagus in manometry. Antisecretory therapy was stated ineffective and subject to correction in 24-h pH-impedance.

Conclusion. Asymptomatic BO-complicated GERD patients comprise a special cohort. The main challenge to prevent progression into oesophageal adenocarcinoma is an adequate personalised patient management leveraging the modern diagnostic techniques, control of antisecretory treatment and its correction a situ.
Liver Damage in Type 1 Diabetes Mellitus
Authors: Bueverov A. O. , Zilov A. V.
Published: June 2021

Aim. An up-to-date review of the prevalence, pathogenesis, diagnosis and management of hepatological complications of type 1 diabetes mellitus (T1D).

Key points. Diabetes type 1 causes a markedly more common liver injury than traditionally assumed. Three types of hepatic damage have been described to date in T1D patients, steatosis, glycogen hepatopathy and diabetic hepatosclerosis, with the latter two apparently pathognomonic of this diabetes type. Their pathogenesis is complex and not fully understood. Its important link is a likely inherited non-physiological insulin supply to the tissue, especially at marked glycaemic fluctuations. An adequate glycaemic control is the main prevention and treatment measure in these conditions. The practitioner’s understanding of liver damage in T1D is an earnest to avoid unnecessary tests and ineffective medications.

Conclusion. Both endocrinologists and internists ought to contemplate the possibility of liver involvement in T1D for improving the patient outcomes.
DA ESCRITA AO REGISTRO DA CENA NA DRAMATURGIA DO ESPETÁCULO QUEM TEM BOCA, VAI A ROMA, QUEM TEM SORTE, AO POLO NORTE
Authors: Fontana Fabiana , De Almeida Thayná Máximo
Published: June 2021

O presente artigo se propõe a analisar a dramaturgia do espetáculo de palhaço Quem tem boca, vai a Roma, quem tem sorte, ao Polo Norte como estratégia de discussão sobre a expansão do conceito dramaturgia no cenário cultural atual. Paralelamente objetiva pensar o impacto desse fenômeno na investigação da dramaturgia como vestígio do fazer artístico. Consequentemente, o trabalho aborda alguns aspectos da problemática que abrange a documentação no teatro, mais especificamente, aquilo que se refere aos registros resultantes do processo de criação, os quais constituem, em parte, fontes de estudo da prática teatral. Palavras-chaveDramaturgia. Cena Contemporânea. Documento de Teatro. Palhaçaria. Processo Criativo.
“ERAM DE TERRA SEUS CORPOS... DE ÁGUA SEUS SONHOS”: INCIDÊNCIAS DE UM PROCESSO CRIATIVO COM AS(OS) MBYA-GUARANI NA FORMAÇÃO DE PROFESSORAS(ES) DE DANÇA
Authors: Da Silva Castro Crystian Danny , Corrêa de Borba Barboza Mônica , Berté Odailso Sinvaldo
Published: June 2021

Este trabalho apresenta reflexões acerca das possibilidades artístico-pedagógicas no campo das artes da cena, em específico a dança, voltadas para a formação de professoras(es). Tais discussões emergem do Projeto de Extensão “De terra seus corpos”, iniciado no ano de 2018 e vinculado ao Curso de Dança – Licenciatura da UFSM. Por meio de diferentes processos criativos, deu-se a remontagem do espetáculo Som e Luz em Corpos, que consiste na coreografia/encenação do tradicional espetáculo de Som e Luz, do Sítio Histórico de São Miguel Arcanjo. Essa obra tem sido apresentada por um elenco composto de estudantes indígenas da Aldeia Guarani Tekoá Koenjú e acadêmicas(os) Universidade Federal de Santa Maria. À luz das compreensões da Ecologia de Saberes (SANTOS, 2010), Epistemologias do Sul (SANTOS, 2019) e Pedagogia da Autonomia (FREIRE, 2015), buscou-se articular um fazer-pensar dança que promova diálogos horizontais entre as epistemologias que operam dentro das universidades e os diversos saberes que são produzidos pelos Mbya-Guarani. Com esse trabalho, percebe-se um enriquecimento na formação das(os) licenciandas(os), sobretudo no que tange à docência em Arte e a elaboração de práticas artístico-pedagógicas contemporâneas, alicerçadas em uma perspectiva de valorização da diversidade e reconhecimento da cultura Guarani na sua história e potencial criativo. Palavras-chaveProcessos Artístico-Pedagógicos em Dança. Comunidade Tekoá Koenjú. Ecologia de Saberes. Epistemologias do Sul. Pedagogia da Autonomia.
TEATRO NO CONTEXTO ESCOLAR: PARA UMA PRÁTICA INVESTIGATIVA, EXPERIMENTAL E COMPARTILHADA
Authors: Rocha Fernanda Marília , Bertoni dos Santos Vera Lúcia
Published: June 2021

O texto apresenta reflexões constitutivas de uma pesquisa envolvendo processos de encenação teatral na Educação Básica, que teve por base empírica uma experiência pedagógica desenvolvida na disciplina de Arte-Teatro junto a jovens estudantes do Ensino Fundamental de uma escola da Rede Estadual do Rio Grande do Sul, configurada como pesquisa-ação e desenvolvida a partir de projetos de encenação teatral propostos em sala de aula. Dentre os subsídios às reflexões sobre a experiência pedagógica e artística vivenciadas nesses processos, destacam-se alguns aspectos do fazer teatral no ambiente escolar, tais como: as relações entre processo e produto na construção de conhecimento em teatro; a perspectiva de compartilhamento da criação artística como inerente à prática teatral; e o caráter eminentemente investigativo da criação em teatro, que se relaciona à sua condição experimental. A reflexão constitui-se a partir de referenciais do campo da  Pedagogia das Artes Cênicas, tais como, Koudela e Almeida Junior (2015), Mendonça (2013),Desgranges (2012) e Pupo (2009), dentre outros, dos Estudos Teatrais, como Dubatti (2003) e da Educação, como Becker (2017). A perspectiva do texto é refletir sobre a presença do teatro na educação escolar de maneira a aproximar a sua prática das formas cênicas proliferadas na atualidade. Palavras-chavePedagogia das Artes Cênicas. Educação Básica.  Experiência Artística. Processo e Produto. Conhecimento.
HÁ COISAS QUE SÓ OS ARTISTAS PODEM FAZER? ARQUIVAR ATRAVÉS DE UMA ESTEIRA DE CORRER
Authors: Felice Bonfim Carolina
Published: June 2021

Este artigo busca compartilhar os métodos e as estratégias do projeto de pesquisa baseado na prática artística Ninety movements on a Technogym G6508D. Nessa pesquisa me concentro no ato de correr a fim de levá-lo ao extremo: fragmentá-lo, arquivá-lo, incorporá-lo e destacar o que há de único e pessoal em cada gesto e em cada forma de movimento. Ninety movements on a Technogym G6508D é a continuação de uma linha de trabalho que venho desenvolvendo ao longo dos últimos anos que, desde uma perspectiva pautada nas artes visuais e na performance, tem como tema central o corpo como arquivo. Palavras-chaveArquivo. Corpo. Incorporação. Metodologia. Pesquisa Baseada na Prática.
DANÇA TAMBÉM É BOM PARA VENDER: USOS DE REPRESENTAÇÕES DE DANÇA NO PROGRAMA “O BOTICÁRIO NA DANÇA”
Authors: Guarato Rafael , Oliveira Irislene Silva de
Published: June 2021

O presente trabalho investiga como a dança foi veiculada no programa “O Boticário na Dança”, partindo da análise do vídeo publicitário “O Boticário na Dança – Beleza em movimento”, com intuito de compreender por quais meios a dança consegue valoração e sentido a ponto de fomentar consumo. Nesse sentido, a dança possui uma economia e mobiliza sentidos para um mercado. Para tanto, o texto estabelece diálogos centrais com debates acerca dos conceitos de indústria cultural, representação e mercadoria pela perspectiva da antropologia contemporânea e da história cultural.
LA DRAMATURGIE AU TEMPS DU « POSTDRAMATIQUE »
Authors: Danan Joseph
Published: June 2021

Quelque chose est en train de transformer en profondeur le théâtre. Hans-Thies Lehmann a eu le mérite de nommer ce phénomène en avançant la notion de « théâtre postdramatique » – même si cette expression est discutable dans la mesure où ces nouvelles formes n’annulent pas nécessairement le drame. Le théâtre du XXe siècle était basé sur le paradigme d’un « art à deux temps » (Henri Gouhier). L’auteur écrit une pièce, puis le metteur en scène s’en empare et la monte. C’est l’utopie d’Artaud, celle d’un « créateur unique », qui semble prendre corps en ce début de XXIe siècle. La dramaturgie se trouve inévitablement affectée par cette évolution : évidemment, dans son premier sens, l’art d’écrire une pièce, lorsque l’écriture et la mise en scène se produisent dans le même mouvement ; mais aussi dans son sens moderne, lorsque le terme s’applique au passage à la scène d’une pièce préexistante. Entre la transformation d’une œuvre dramatique en matériau pour la scène, sans prendre en compte sa structure dramatique, et l’imposition d’une « grille de lecture » rigide, il devrait y avoir encore place pour une dramaturgie ouverte et sensible, créant les conditions d’une expérience pour le public.Mots-clésDramaturgie. Dramaticité. Ecriture dramati- que. Théâtre « Postdramatique ». Performance. Expérience.
Como a história da escravidão pode ajudar a formar uma teoria brasileira do direito? | How can the history of slavery inform a Brazilian theory of law?
Authors: Pereira Paulo Henrique Rodrigues
Published: June 2021

ResumoO direito brasileiro foi articulado em torno das categorias clássicas do liberalismo europeu. Para além do debate da compatibilidade entre liberalismo e escravidão, esse artigo pretende demonstrar como a necessidade de preservar uma escravidão semilegal constituiu institucionalidades que fizeram com que o direito brasileiro operasse problematicamente sob o registro da tradição liberal, mesmo em relação aos seus cidadãos livres. Isso não foi um “erro” do direito, uma falha, mas foi antes uma ação inteligível dos arquitetos das formas e modos de funcionamento da juridicidade nacional. Nesse sentido, esse artigo pretende apontar para a necessidade de construção de uma teoria brasileira do direito que dê conta de compreender as particularidades de um sistema jurídico profundamente afetado pelo escravismo do século XIX.Palavras-chave: História do Direito. Teoria do Direito Brasileiro. Direito da Escravidão. AbstractBrazilian Law was crafted around the classical categories of European liberalism. Beyond the debate regarding the compatibility between liberalism and slavery, this paper intends to show how the need to preserve a semi-legal slavery system created illegalities that highlighted the contradictions between Brazilian Law and the liberal tradition. The resulting tensions also created consequences for free citizens, which are the focus of this paper. It demonstrates that these consequences were not mere legal defeasibility, but rather an intelligible action shaping the national legal system. The article advocates for the necessity to build a Brazilian theory of Law that takes these aspects into consideration, accounting for the systematic impact of 19th-century slavery on the idea of legality in Brazil.Keywords: Legal History. Brazilian Theory of Law. Slavery Law.
Culturas indígenas e a ideia de nação brasileira | Indigenous cultures and the idea of a Brazilian nation
Authors: Silveira Maria de Fátima Souza da
Published: June 2021

ResumoO Estado brasileiro buscou apagar a diversidade de povos e culturas que caracterizam o país por meio da imposição da ideia de uma "brasilidade homogênea". Para a historiografia “nacional” que surgia após a Independência, o início da história do Brasil significava o fim dos povos indígenas, que “foram excluídos enquanto atores históricos” e “invisibilizados pelos discursos políticos e intelectuais” até a década de 1980, momento em que emergem “como sujeitos de sua história”. Partindo do diálogo entre a historiografia indígena e a antropologia, nosso objetivo é refletir sobre o tema das culturas indígenas e a ideia de nacionalidade brasileira construída pelas elites brancas depois da Independência.Palavras-chave: Culturas indígenas. História indígena. Nação brasileira. AbstractThe Brazilian State intended to "dissolve" the diversity of people and cultures that characterize the country through the imposition of the idea of "homogeneous Brazilianness". For the “national” historiography that emerged after Independence “the beginning of the history of Brazil meant the end of the Indians, who “were excluded as historical actors” and “made invisible by political and intellectual discourses” until the decade 1980, when they emerge “as subjects of their history”. Based on the dialogue between indigenous historiography and anthropology, our aim is to reflect on the theme of indigenous cultures and the idea of Brazilian nationality built by white elites after Independence.Key words: Indigenous cultures. indigenous history. Brazilian nation.
Tentativa II | Attempt II
Authors: Salomão Omar
Published: June 2021

Trata-se de um ensaio visual onde o autor nos convida para com ele embarcar em uma viagem/meditação entre imagens e discursos, depois de sermos, junto dele, confrontados com o punctum de post-its e cartões postais de sua parede. As diminutas notas para si mesmo e as pinceladas sinuosas de uma pintura de Van Gogh descortinam uma investigação tateante sobre o problema da não-figuração (que Salomão designa como abstração) nas artes e sobre o trabalho psíquico do sintoma: cerne da subjetividade, deiscência existencial e origem do discurso, conforme pensou Lacan. Nesse sentido, os artistas e escritores loucos seriam, na melhor tradição artística hölderliniana, aqueles capazes de capturar um pequeno brilho/acontecimento na realidade que teima em se apagar.
Sem máscaras: uma antologia dentro de casa, na quarentena | No More Masks: an antology from our homes, during the quarantine
Authors: Malmaceda Ana Laura Boeno , Sant’Anna Alice , Lins Catarina , Lutterbach Maria , Mariutti Sofia
Published: June 2021

Coletânea de poemas e imagens.
A improrrogável crítica da identidade nacional no Brasil
Authors: Rosenfield Kathrin , Malmaceda Ana Laura Boeno , Mautone Guilherme
Published: June 2021

Apresentação do dossiê temático "Culturas Brasileiras Contemporâneas".
Controllability Analysis for Impulsive Integro-differential Equation via AB Fractional Derivative
Authors: KALIRAJ KALIMUTHU , Thilakraj E. , C Ravichandran , Nisar Kottakkaran
Published: June 2021

In this work, we analyse the controllability for certain classes of
impulsive integro - differential equations(IIDE) of fractional order via
Atangana Baleanu derivative involving finite delay with initial and
nonlocal conditions using Banach fixed point theorem.
Ten principles for achieving scientific impact with integrity in policy and management
Authors: Thompson Ross , Barbour Emily , Bradshaw Corey , Briggs Sue , Byron Neil , Grace Michael , Hart Barry , King Alison , Likens Gene , Pollino Carmel , Sheldon Fran , Stewardson Michael , Thoms Martin , Watts Robyn , Webb James
Published: June 2021

In the face of mounting environmental problems, it is essential that
accurate and timely scientific information is available to inform policy
development and guide management. Scientists have specialised knowledge
necessary for evidenced-based decision making, but despite extensive
literature on the interface between science and policy, there is little
guidance on achieving policy relevance while maintaining high standards
of scientific integrity. Here, we provide a set of principles for
environmental scientists to engage with policy makers and environmental
water managers. We propose the adoption of a contemporary pluralistic
approach using a diversity of modes of engagement between scientists,
policy makers, and managers. We define a set of ‘roles’ for
environmental scientists to engage effectively with policy and
management, and discuss the advantages and pitfalls of each. We
illustrate the breadth of modes of engagement at the
science-policy-management interface using an example from Australia’s
largest river system, the Murray-Darling Basin. We challenge the
anachronistic, yet persistent concept that engaging with industry or
government compromises the objectivity of involved scientists. We argue
that there are multiple assurance processes in place to protect
scientific integrity. Society needs scientists to be actively involved
in finding solutions to the many urgent environmental issues we are
facing, and if our principles are followed there are opportunities for
healthy interaction between science, policy, and management.
Supporting Information for "Ring Origami: Snap-folding of Rings with Different Geometries"
Authors: Wu Shuai , Yue Liang , Jin Yi , Sun Xiaohao , Zemelka Cole , Qi H. Jerry , Zhao Ruike Renee
Published: June 2021

Through experiment and simulation, we study a kind of deployable thin
circular ring that can be folded into three small loops.  Parametric
study is conducted on the ring to study the geometric parameters that
can influence ring’s buckling .We also explore the rings with other
shapes , such as elliptical rings, rectangular rings. Some applications
basing on these studies are shown in this paper.
CAMEO - Perspectives on the future of fully automated evaluation of structure prediction methods
Authors: Robin Xavier , Haas Juergen , Gumienny Rafal , Tauriello Gerardo , Schwede Torsten
Published: June 2021

The Continuous Automated Model EvaluatiOn (CAMEO) platform complements
the biennial CASP experiment by conducting fully automated blind
evaluations of 3D protein prediction servers based on the weekly
pre‐release of sequences of those structures, which are going to be
published in the upcoming release of the Protein Data Bank (PDB). While
in CASP14 significant success was observed in predicting the structures
of individual protein chains with high accuracy, significant challenges
remain in correctly predicting the structures of complexes. By
implementing fully automated evaluation of predictions for
protein-protein complexes, as well as for proteins in complex with
ligands, peptides, nucleic acids, or proteins containing non-canonical
amino acid residues, CAMEO will assist new developments in those
challenging areas of active research.
Postoperative acute heart failure in an 18-year-old McCune--Albright syndrome patient without preoperative cardiac morphology abnormality -- a case report and literature review
Authors: Wu Rongjie , Fu Guangtao
Published: June 2021

An 18-year-old female patient diagnosed with McCune–Albright syndrome
(MAS) developed postoperative acute heart failure with negative findings
during preoperative cardiac screening and restricted fluid infusion.
Latent cardiovascular involvement of MAS could be a reasonable
explanation for the present case.
General vs. Regional Anesthesia and Neonatal Data (GRAND). A Retrospective Propensity Score Matched Study.
Authors: Cojocaru Liviu , Salvatori Cristiana , Amir Sharon , Seung Hyunuk , Nyman Katherine , Kodali Bhavani , Turan Ozhan
Published: June 2021

Objective To evaluate whether there is a difference in immediate
neonatal outcomes with general anesthesia (GA) vs. regional anesthesia
(RA) when induction of anesthesia to delivery time (IADT) is prolonged
(≥10 minutes). Methods This is a retrospective case-control study that
included cases from July 2014 until August 2020. We reviewed all
singleton pregnancies delivered between 24 and 42 weeks of gestation
with IADT ≥ 10 minutes. The propensity score (PS) matching method was
performed using baseline characteristics. Analyses were performed with
SAS software version 9.4. Results During the study period, we identified
258 cases meeting inclusion criteria. After the PS matching was applied,
the study sample was reduced to 60 cases in each group. The median IADT
was similar between groups [41.5m (30.5,52) vs. 46m (38-53.5),
p=0.2]. There was no significant difference between groups with
respect to arterial cord pH [7.24 (7.21,7.26) vs. 7.23 (7.2,7.27),
p=0.7]. Nor were there any associations between maternal
characteristics and Apgar score at 5 minutes except Apgar score at 1
minute (p<0.001). No significant difference was identified in
the rate of admission to the neonatal intensive care unit (NICU) [11
(52.4) vs. 10 (47.60], p=0.8] or NICU length of stay between GA vs.
RA [4(3-14) vs. 4.5(3-11), p=0.9]. Conclusion Our data indicate that
with prolonged IADT, favorable neonatal outcomes are seen with both GA
and RA, in contrast with previous studies performed decades ago. This
underscores the need for re-appraisal of historic outcomes reflecting
new modalities, techniques, and advances in the medical field.
The effect of Hydroxychloroquine use due to rheumatic disease on the risk of Covid-19 infection and its course
Authors: Korkmaz Tanzer , Şener Aslı , Gerdan Vedat , Kızıloglu İlker
Published: June 2021

Introduction COVID-19 virus continues to spread and die worldwide. Some
studies examining hydroxychloroquine as a prophylactic agent reported
that its efficiency and reliability have not been proven so that it must
not be used for prophylaxis other than clinical researches. However we
think that the results of this study we conducted in a local area will
contribute to the literature data. Methods The study was designed as
adult patients who were in follow-up taking HC due to their chronic
diseases were included. 384 patients who were taking hydroxychloroquine
regularly and 299 patients who were not taking hydroxychloroquine were
included. The primary outcome of this study is to detect a positive PCR
result in patients who received a PCR test and to determine the
incidence rate and its course of the disease among those who were taking
HC and those who were not taking hydroxychloroquine. Results The
majority of the patients (median age: 51.8- range 17-89) were women and
housewives. In the patient group using hydroxychloroquine, 22 patients
were tested for PCR and only 2 positive patients were found. Covid-19
was detected in 24 (8.02%) of 65 (21.73%) patients who underwent PCR
test at Control group (n = 299). PCR positivity was statistically lower
in the HK group (n = 2, 0.52%, n = 24, 8.02%, respectively, p =
0.0001). Conclusions Our study supported the fact that there is a lower
PCR positivity and symptoms are milder among patients who are using HC
regularly, as compared to those who are not using hydroxychloroquine.
Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta-analysis
Authors: McNally Ryan , Farukh Bushra , Chowienczyk P J , Faconti Luca
Published: June 2021

Aim: Different to inhibitory drugs of the renin-angiotensin-aldosterone
system (RAAS), diuretics are known to decrease blood pressure (BP) and
stimulate renin release by the kidneys. Despite plasma aldosterone (PA)
level is mostly regulated by the RAAS activity, serum potassium has been
shown to be an important factor in animal models and humans. Here we
perform a systematic review and meta-analysis of randomized-controlled
trials investigating the effects of diuretic therapy on PA and its
correlation with change in potassium and BP. Methods: Three databases
were searched: MEDLINE, EMBASE and The Cochrane Central Register of
Controlled Trials (CENTRAL). Titles were firstly screened by title and
abstract for relevancy before full-text articles were assessed for
eligibility according to a pre-defined inclusion/exclusion criteria.
Results: A total of 1139 articles were retrieved of which 45 met the
pre-specified inclusion/exclusion criteria. The average standardised
difference in mean PA change was similar for all classes of diuretic
(mean, 95% CI); thiazide/thiazide-like 0.304 (0.169, 0.440), loop 0.927
(0.37, 1.49), MRA/potassium-sparing 0.264 (0.174, 0.355) and combination
0.466 (0.142, 0.789), Q = 6.475, P = 0.091. In subjects previously
untreated with another antihypertensive, there was a significant
relationship between PA change and change in systolic BP but no
relationship with the change in potassium. Conclusion: In RCTs of
diuretic therapy in hypertension, there is an increase in PA with all
classes of diuretic and no between-class heterogeneity. Change in PA is
not related with potassium but correlates to the change in BP in
subjects previously untreated with another antihypertensive medication.
Human Rights Education and Language Learning in Pakistan: An EFL Perspective
Authors: Tehseem Tazanfal , Zahra Bokhari  , Saba Zulfiqar
Published: June 2021

This paper explores the dissemination of human rights through English language learning in Pakistan and builds on the knowledge that contributes to the development of democratic educational outcomes. Textbook discourses have long been the domain of critical linguistics; critical linguists understand textbook discourse primarily as a language in the context of schooling while the discourse analysts understand such discourses as systems of knowledge and ideology. The question of how the learners are expected to engage with the subject knowledge is explored from two theoretical perspectives: linguistic analyses are executed using tools such as choice of pronouns, mood, and modality from Systemic FunctionalLinguistics (Halliday et al., 2014), a social semiotic theory of language as a meaning potential, and reinterpreted according to the intercultural paradigm (Piller, 2010) to familiarize the ways interactants choose to build relations in the textbook narratives because in exploring interpersonal meanings it is very easy to focus on what is said and why. Additionally, the image analysis is done by representational analysis that of how images reflect ideologies (Kress & VanLeeuwen., 2006). The contributions of this study are of particular importance to make visible elements of interpersonal meaning-making which were explored in the context of cumulative knowledge building in humanities.
Understanding the Concept of Sustainable Food Consumption – whether it will Reduce Meat Consumption
Authors:   Warsaw University of Life Sciences, Rejman Krystyna , Jeżewska-Zychowicz Marzena ,   Warsaw University of Life Sciences, Ganczewski Grzegorz ,   Biopolymers and Chemical Fibres Institute Warsaw Branch
Published: June 2021

Despite the evidence-based health and environment benefits of sustainable diets and the urgent need to change consumption patterns in well-developed countries into plant-based diet, people are reluctant to limit meat consumption. The aim of the study was to examine the attachment to meat consumption in a group of Polish consumers and whether it depends on an understanding of the concept of sustainable food consumption (SFC). The study was carried out using the Computer Assisted Web Interview method on a sample of 199 consumers, who met two criteria of inclusion: age (20 - 65 years old) and not excluding meat from the diet. The questionnaire included a tool to measure the attachment to eating meat in 4 dimensions: hedonism, affinity, entitlement, and dependence. The analysis of the results was carried out in the Statistica software. Pearson Chi-squared test and Student’s t-test were performed to investigate the significance of differences between the two variables (p≤0.05). In the surveyed group only 35 % of respondents interpreted the term of sustainable food consumption correctly and among them there were more people with higher education. Interviewees were rather strongly attached to eating meat and this was firstly due to the belief in human right to eat meat, secondly – taste preferences and hedonism, thirdly ‒ dependence on eating meat. The ethical motives (affinity) were rated lowest, but significantly higher by respondents understanding the concept of sustainable diet. Their opinions on all aspects of attachment to eating meat were more pro-environmental than those of respondents who did not understand the idea (although the differences in the opinions were not statistically significant). Our results indicate the need to implement effective educational programs that will show all benefits of a sustainable diet to provide consumers with reliable knowledge and on this basis influence their attitudes and support them in making healthier and more sustainable choices in the food market.
Gamification and Using It in Organisational Consulting
Authors:   RISEBA University of Applied Sciences, Zakrizevska-Belogrudova Maija , Leimane Sanita ,   RISEBA University of Applied Sciences
Published: June 2021

Gamification has been a topical item in education, marketing, human resources management, business, and organisational consulting in the past decade. Nowadays, companies have a wider range of available organisational consultations: organisational supervision is developing, coaching is popular, and there is a wide offer of business training sessions. This study aims to research gamification in organisational consulting, analyse the differences in the opinions regarding the use and availability of gamification in the professional activities of coaches, supervisors and business trainers. The survey developed by the authors of the study consisted of four sets of items (Information about Gamification, Application and Availability of Gamification, Believing Gamification Methods, Team/Group Responsiveness to Gamification) and two additional statements for the purpose of confirming the responses given by the respondents regarding their beliefs in gamification as an effective method and their readiness to use it. The associations related to the game and gamification were also researched. The questionnaire about gamification in the professional activities of supervisors, coaches and business trainers was sent electronically to professionals practising in Latvia. Questionnaires from 85 respondents were received and processed. The results demonstrated no statistically significant differences in the opinions of coaches, supervisors and business trainers regarding the use of gamification in organisational consulting. It was found out that the concept of gamification has not been sufficiently explained and there is still no common understanding regarding it in Latvia. More than half or 55 % of the 85 respondents in the survey do not know where to acquire gamification. At the same time, 91 % of the respondents in the survey specify that they are willing to acquire the methods of gamification. The authors of the study believe that it is important to proceed with the research in organisations to find out the experience of the organisations in gamification and to develop gamification training programmes for the organisations.
Fabrication of Porous Anorthite Ceramics Using Eggshell Waste as a Calcium Source and Expanded Polystyrene Granules
Authors: TORMAN KAYALAR Merve , ERDOĞAN Gökhan , YAVAŞ Ahmet , GÜLER Saadet , SÜTÇÜ Mücahit
Published: June 2021

Within the scope of present work, porous and lightweight anorthite ceramics by utilizing admixtures of eggshell waste, fireclay, and expanded polystyrene (EPS) addition has been produced. First, samples of mixtures prepared with different proportions of eggshell waste were fired at different temperatures in order to determine the appropriate anorthite composition. Later, in order to produce high porosity anorthite ceramics, different amounts of EPS are added to the most suitable composition determined and porous samples were produced by firing at the certain temperature. The high degree of porous anorthite ceramics from the admixtures in the range of 0 to 30 vol.% EPS addition were satisfactorily fabricated. The physical characteristics, compressive strength and thermal conductivity were examined. Thermal conductivity of the anorthite ceramics showed a decline from 0.39 W/m·K (1.00 g/cm3) to 0.11 W/m·K (0.78 g/cm3) in proportion to the decrease in density. It has been found from the results in which these porous materials produced by the reuse of eggshell waste are suitable for use in various applications requiring elevated temperatures.
Self-regulated Learning Model Affects Students’ Mathematical Conceptual Understanding and Self-confidence in terms of Cognitive Styles
Authors: Mahayani N. P. L. , Astawa I. W. , Suharta I. G. P.
Published: June 2021

The main problem in mathematics learning is to form students’ understanding and self confidence. The aim of this study is to analyze the impact of self-regulated learning model on conceptual understanding and self-confidence in terms of cognitive styles. This study was a quasi-experimental study which applies treatment by level design, where the treatment is learning model for students with different cognitive style level. The samples of the study are 80 students in four classes, who are selected using cluster random sampling technique. Data on conceptual understanding are collected by using conceptual understanding test in the form of essay test. While the data on the students’ self-confidence are collected using questionnaires. The data collected are anayzed using manova. The results of the study indicate that self-regulated learning has positive impact on the students’ conceptual understanding and self-confidence (F = 8,796; p < 0,05). Thus, it could be concluded that learning model and cognitive style give significant impact on the students’ conceptual understanding and self-confidence in terms of cognitive styles.
Blended Learning for Medical First Responder Training: Needs Analysis
Authors: Herlinawati Herlinawati , Tarjiah Indina , Wirasti Murti Kusuma
Published: June 2021

The rapid development of technology demands a fast, easy, cheap, effective, and efficient system and can be accessed anytime and anywhere, including education and training. In the world of education, technological progress is marked by the number of people using the blended learning model. This study aims to obtain and collect information, data, and opinions from stakeholders and training participants at the Training Center of National Search and Rescue Agency to develop a blended learning model for Medical First Responder Training for responders. This study uses the Research and Development (RnD) method with the Integrative Learning Design Framework development model and the PEDATI development strategy. This research is limited only to the initial analysis stage, namely in the form of field studies and literature studies to determine the needs of the Medical First Responders Education and Training and the needs of students who will be the first steps in developing blended learning of MFR training for rescuers within the National Search and Rescue Agency. This study indicates that the National Search and Relief Education and Training Center needs an effective and efficient learning model, coupled with the training participants' responses indicating that they wish to have alternative learning sources. The results of this need analysis research can serve as the basis for the development of blended learning training in Medical First Responder.
Professional Development Activities of IELTS Trainers from Non-English Major
Authors: Wulandari Nur Setyo , Yudi Cahyono Bambang , El Khoiri Niamika
Published: June 2021

Professional development activities are done by English teachers from formal educational institutions and by trainers from non-English majors who teach IELTS preparation program in non-formal educational institutions. This study investigated the professional development activities done by IELTS trainers from non-English majors and how the professional development activities help them improve their teaching competencies. A case study design was applied, and an in-depth interview and documentary analysis were used to gain the data. Four selected research subjects were involved in this study. The results showed that the IELTS trainers' professional development activities include collaborative and independent learning activities. Furthermore, those activities help the IELTS trainers from non-English majors positively as they can fulfill their demand to improve their teaching competencies since there is limited institutional support for them in professional development. Therefore, the institution where the IELTS trainers work should provide adequate formal learning supports. In addition, the IELTS trainers in this study and other IELTS trainers should be involved in other informal learning activities more frequently.
Basic Chemistry Practicum Handbook with Occupational Health and Safety (K3) to Prevent Work Accidents in Laboratory: Validity and Feasibility
Authors: Sudiana I Ketut , Suja I Wayan
Published: June 2021

First year students of the Chemistry Education Study Program have some problems in practicum because the students' basic laboratory skills are low. The current practicum guide is not sufficient to provide information on basic skills for working in the laboratory. This condition causes students to have problems practicum and there is a potential risk of accidents. This study aims to produce a handbook for Basic Chemistry I with Occupational Health and Safety (K3) which is feasible to be implemented in Basic Chemistry Practicum I. This research was a Research and Development (R&D) with a 4-D development model, consist of 4 main stages, Define, Design, Develop and Disseminate. The research was limited to the development stage, which ended in the legibility test. Based on expert assessment the results showed that the handbook for Basic Chemistry Practicum I with K3 was very valid in terms of content (3.75), language (3.70), and media (3.6) from a maximum score of 4. The results of the readability test from 9 students showed that all students gave clear assessments. They understood the contents and guidelines for practicum on Basic Chemistry 1 with K3 very well. The conclusion of this study is Basic Chemistry Practicum I Handbook with K3 content is valid to be implemented from the aspects of content, presentation, language, media, and readability.
Enhancing Students' Reading Comprehension Through Two Stay Two Stray (TSTS) Technique
Authors: Asdar Asdar
Published: June 2021

Reading is one of the techniques in learning that is often involved in classroom practices, and Two Stay Two Stray is one of the methods introduced in the cooperative learning process. This study aims to find out how the Two Stay Two Stray technique improved students' reading comprehension. This research focused on applied classroom action research. The population of this research was the students of the English Education Department. This research was used to take one class as the research sample, which consists of 32 students.  The instrument of this research was a multiple-choice test. There are two cycles in this research. The result shows that students' mean score in cycle 1 was 59,68 and in cycle 2 was 75,31. Based on the results, the Two Stay Two Stray technique was successful. Therefore, it can be inferred that the Two Stay Two Stray technique strengthened the students' reading comprehension. In addition, the students were more interested and inspired to join the class, and they were excited during the teaching-learning process, based on the results of the observation sheet.
The Need Analysis of Student Worksheet for Writing Drama Script of Seventh Grade Student
Authors: Simbolon Desi Efrina , Indrawati Sri , Ernalida Ernalida
Published: June 2021

This research aims to describe the results of the learners’ needs toward the drama script writing material development using a scientific approach. This research applied a qualitative approach. The data were collected with observation, questionnaire, and interview techniques. The applied instruments were observation, questionnaire, and interview. The sample consisted of learners. The findings showed that the learners needed communication and technology-based teaching materials to support their needs of drama script writing skill training. Based on the learners’ characteristics identification, they needed learning application to make the learning activities and to freely enrich the sources. They also needed interesting teaching materials that had many examples, provided writing exercises, the opportunity to interact, time to work the exercise, and space to perform. Therefore, this research proposed Moodle application as a learning material in the form of a Student Worksheet. This initial stage of research is expected to be the beginning of drama script writing material development with a scientific approach and based on Moodle. The results of the learners’ need analysis could be also used by other researchers to obtain the 21st-century learners’ characteristics.
Instrumento para evaluar los conocimientos matemáticos previos para la enseñanza del concepto de límite durante la pandemia SARS-CoV-2
Authors: Rojas Maldonado Erick Radaí , Toscano Galeana Jaqueline
Published: June 2021

El objetivo del presente trabajo fue diseñar un instrumento que permitiera determinar, en el marco de la actual emergencia sanitaria generada por el virus SARS-CoV-2, los conocimientos matemáticos previos en torno al concepto límite de alumnos del bachillerato de Ingeniería y Arquitectura (sección 1) del Colegio Primitivo y Nacional de San Nicolás de Hidalgo. Para el diseño del instrumento se siguieron las cuatro fases de construcción que establece Soriano Rodríguez (2015), es decir, 1) objetivos, teoría y constructo, 2) validación juicio de expertos, 3) prueba piloto y 4) validación psicométrica. Los resultados de esa última fase demuestran que el instrumento se puede reproducir en diferentes muestras sin que constituyan un gran sesgo por parte de los participantes. Además, los puntajes de cada pregunta fueron consistentes con el puntaje total del instrumento. En conclusión, se puede afirmar que esta puede ser una herramienta muy útil no solo para detectar los conocimientos previos que los alumnos tienen en cuanto al cálculo diferencial, sino principalmente para crear estrategias didácticas que permitan atender esas debilidades a partir de los estilos de aprendizaje de los estudiantes.