bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Employees Perception of Wema Bank Internal Communication Strategies in the Management of COVID-19 Pandemic
Authors: Dada Gloria Cynthia
Published: October 2023

The study assessed employees’ perception of Wema Bank internal communication strategies inthe management of COVID-19. The objectives of the study were to assess the strategies adopted by Wema Bank internal communication before and during COVID-19 pandemic with a view to evaluating the level of workers’ satisfaction with the strategies adopted by the bank. The study was premised on Organizational Information Theory. The study adopted survey design with structured questionnaire as instrument of data collection through which two hundred and ninety-four (294) respondents were sampled from one thousand, one hundred and nine staff members of Wema bank branches across three states of Lagos, Ogun and Oyo. Findings showed that 83.1% of the respondents have communication engagement with the management of Wema bank daily, while others indicated less frequently. Prior to the pandemic, they communicated through multiple channels such as face to face (92.2%); individual official mail (96.1%), memo and circular (36.3%), WhatsApp messaging (22.1%), Zoom (18.8%) and notice board (12.3%), heads of departments (94.1%), corporate communication (96.8%) line managers (90.9%). During the COVID-19 pandemic, 47.4% of respondents that they received information from the management daily during 19.5% said weekly, 8.4% said monthly, while 24.7% said as the need arose. At this time, Wema bank management communicated majorly through individual E-mail (98.1%), WhatsApp loop (92.2%), Zoom (98.7%), corporate communication (96%), heads of departments (96.8%). and line managers (98.1%). 97.4% of the respondents indicated Internet/Online based communication as the major form of communication channel during COVID-19 outbreak. So, there was increased reliance on digital channels with pressure on technology infrastructure and resources. It was concluded that strategic communication effectively applied in crises contexts, enlists the employees as corporate brand disciples who are comm
An Analysis of Lagos Audience Perception of Channels Business Morning Programme on Investor Relations
Authors: Elizabeth Edache-Ochekwu , Udoudo Aniefiok Jackson , Nwachukwu Faustinus Ginikanwa
Published: October 2023

This study analysed the perception of Channels’ Business Morning programme on investor relations in Lagos. The objectives of the study were to: find out the extent of exposure of audience in Lagos to Channels’ Business Morning programme; investigate the perception of audience in Lagos of Channels’ Business Morning and ascertain whether or not the perception of audience in Lagos of Business Morning translates to investment decision. The survey research design was employed for the study. The population of the study was 2,952,861 from selected cities in Lagos, with 384 as the sample size using the Keyton’s table. The questionnaire was the instrument for data collection. Among others, the study found out that there is a high level of exposure to Channels’ Business Morning programme in Lagos. It also showed that respondents held positive perception of the programme as a valid and objective source of business news and investment- related information. The researchers recommended that citizens should take advantage of their exposure to financial programmes such as Channels’ Business Morning to continually increase their understanding of finance and investments and improve their financial wellbeing. Corporate organisations should leverage on financial media programmes such as Channels’ Business Morning, to enhance their engagement with shareholders and potential investors by making available accurate and transparent financial information. T
Computer-Based Competencies Needed by Administrative Supervisors and Executive Secretaries for Effective Work Performance: A Case of Universities in South-South, Nigeria
Authors: Linda Aninye-Ranor Chineze , Fredrick Idele Emezamena
Published: October 2023

In recent times, the issue of computer based competencies is crucial for the survival of secretaries and their administrative supervisors for effective work performance and advancement in career. Yet, many secretaries and their administrative supervisors are technologically lagging behind and secretarial/office information management students in our universities are not sufficiently exposed to computer technologies in modern office, hence, the need to examine whether computer-based competencies by administrative supervisors and secretaries are needed for effective work performance among selected universities in South-South region of Nigeria. The study adopted descriptive survey design and two (2) research questions and two (2) research hypotheses were developed. The study population consists of one hundred and forty-six (146) secretaries and administrative supervisors. Data gathered through questionnaire were tested for reliability via the test-re- test method and the Cronbach alpha reliability result of 0.97 was obtained. Descriptive statistics(mean and standard deviations) were used to provide answers to the research questions while inferential statistics (Z-test) was employed to validate the relevant hypotheses. Findings showed that database management and PowerPoint presentation applications are needed by secretaries and administrative supervisors for effective work performance. On the basis of the findings, relevant recommendations were made proffered towards improving the performance of secretaries and administrative supervisors in Nigerian universities.
Implementasi Metode Waterfall pada Sistem Informasi Penjualan Unit Motor Berbasis Web
Authors: Mahardika Fajar , Mustofa Kholil , Suseno Akrim Teguh
Published: October 2023

Keberhasilan suatu perusahaan dalam mencapai target penjualan sangat dipengaruhi oleh pemasaran yang baik. Strategi perusahaan merupakan wujud yang terarah dibidang pemasaran. CV ICON TEKNO berkomitmen untuk memberikan solusi mengenai teknologi serta memberikan dukungan kepada pelanggan yang baik. sistem informasi berbasis web agar perusahaan dapat mengolahnya untuk memasarkan barang sesuai dengan kebutuhan produk konsumen. Integrasi dan koordinasi merupakan elemen penting dalam upaya mensinkronkan proses penjualan perusahaan sehingga bila dilakukan dengan baik, efisiensi biaya tercapai dan menguntungkan perusahaan. Tujuan penulisan laporan ini adalah untuk mengetahui peranan strategi pemasaran yang dilakukan CV ICON TEKNO dan memberikan sumbangan pemikiran kepada perusahaan agar meningkatkan volume penjualan serta kegiatan pemasarannya. Metodelogi yang digunakan yaitu Waterfall dalam pembuatan sistem. Hasil dari penelitian dengan penerapan system ini akan sangat membantu dalam pengolahan data transaksi penjualan unit motor. System informasi penjualan unit motor memudahkan petugs dalam pengolahan data, pencatatan menjadi lebih efektif, efisien dan laporan yang dihasilkan akan lebih akurat.
Concepciones sobre pedagogía, maestro y práctica pedagógica de docentes y estudiantes de pedagogía infantil
Authors: Palomeque-Quiñonez Yamileth
Published: October 2023

Durante el transcurso de los estudios de licenciatura, se construyen concepciones individuales sobre pedagogía, maestro y práctica pedagógica que muestran concordancia disímil entre el conocimiento de la teoría pedagógica y el ejercicio profesional. En este artículo se estudiaron las concepciones sobre los citados conceptos, en docentes y estudiantes de la licenciatura en Pedagogía Infantil, Universidad Minuto de Dios (Valle del Cauca, Cali, Colombia). A partir de la hermenéutica reflexiva se discute sobre el maestro como un intelectual, la pedagogía como su saber y la práctica pedagógica como un ejercicio de constante reflexión. Se presentan los resultados de una entrevista semiestructurada, aplicada a cinco profesores y 73 estudiantes, cursantes de séptimo, octavo y noveno semestre. Se evidencian indicadores de tensión en las relaciones entre la formación, la pedagogía, el maestro y la práctica pedagógica, dado que estudiantes y maestros formadores no relacionan el estatus teórico pedagógico con las condiciones de maestro.
Temas Selectos en Salud Mental Tomo 3
Authors: Cañón Ramirez David Steven , Sánchez Alquinga Diana Aracely , Cando Martínez Lorena Carolina , Zumba Paguay Jeniffer Yazmin , Chuquisala Dutan Elvia Veronica
Published: October 2023

"Temas Selectos en Salud Mental Tomo 3" se destaca como un recurso académico y clínico invaluable para psiquiatras, psicólogos y otros profesionales de la salud mental. Este tercer volumen de la serie se enfoca en áreas especializadas y emergentes en el campo de la salud mental, incluyendo la psicofarmacología avanzada, la neuropsiquiatría y los trastornos del espectro autista.
Relationship between Urinary Tract Infections and Various BMI Categories: A Prospective Research Study
Authors: Babu Srikurmam Anil , Devi N. Prabhavathy , Praveen Gadde , Chandra T. Jaya , Krishna L. Radha
Published: October 2023

Introduction:  Throughout the globe, there is increase in obesity as well as Urinary Tract Infection (UTI). Body mass index (BMI) and low socio economic status were reported to be the risk factors of UTI. There were no reports on in this area. Hence a study was conducted to find the correlation between sociodemographic features and the incidence of UTI.

Methods: It was a prospective research conducted from May 2021 to May 2022. Individuals aged > 18 with the symptoms of UTI were included, malignant individuals, those on steroid treatment were excluded. The participants clinical history was recorded in the proforma. Sociodeconomic data was recorded as per the Modified Kuppuswamy scale and BMI was estimated by entering height and weight in the National Institute of Health (NIH) website and divided in to 4 categories. Sample size, specimen collection, culture were practised as per the guidelines. Logistic regression analysis was applied and P <0.05 were considered to be statistically significant.

Results: UTI was detected in 322 (100%). The mean age of the study members was 37.2 years, 123 were male and 199 were female participants, the female male ratio was 1.7. Highest number of UTI was detected in lower class (78; 24.2%) followed by middle class (73; 22.7%), upper class (64; 19.8%), upper middle class (59; 18.3%) and lower middle class (48; 24.2%). Maximum (102; 31.7%) UTI was diagnosed in obesity followed by over weight (96; 29.8%). Logistic regression analysis did not show any association between BMI and UTI (OR = 0.986, 95% CI: 0.923-1.024, P = 0.810).

Conclusions: UTI is common among sexually active female. As per the study findings low socioeconomic status and obesity are the common risk factors for UTI. Hence individuals with a high BMI should be evaluated for UTI if symptoms are noticed.
La neurotecnología educativa: estrategia didáctica para mejorar la atención en estudiantes de educación básica
Authors: Barreto Ramírez Ximena Madelaine , Pendolema Diana M , Moreira Rivera Jhonny Miguel , Arteaga Gualan Fátima Fernanda , Marcillo Ponce Ruth Ximena
Published: October 2023

Los avances tecnológicos han permitido innovar en diferentes disciplinas de la ciencia, y la educación no es la excepción, por ello, se plantea a la neurotencología educativa como la nueva ciencia que aborda el conocer cómo funciona el cerebro y en función de este, implementar herramientas tecnológicas que respondan a la necesidad del estudiante, por ejemplo, en los procesos psicológicos como la atención, pues, es considerado como un punto clave para generar aprendizajes significativos. El presente estudio busca explorar aspectos relacionados con la neurotecnología educativa para mejorar la atención en estudiantes de Educación Básica. Se basó en una investigación de enfoque cualitativo con nivel descriptivo, por lo que, se empleó una revisión bibliográfica para explorar y recopilar aspectos de las divulgaciones científicas relacionados al tema en cuestión desde diversas fuentes como: Google Scholar, Scielo, Redalyc y repositorios académicos de postgrado. Se definen aspectos de la neurotencología educativa como la alternativa para modificar los procesos del cerebro, además de facilitar la construcción del conocimiento en el estudiante, y la capacitación del docente en conocimientos básicos del cerebro y uso de los recursos tecnológicos en el aula.
Estimulación cognitivo – conductual en niños con trastorno por déficit de atención e hiperactividad utilizando música y el idioma inglés
Authors: Pérez Alexis , Enríquez Gabriela , Andrade Fernanda , Bolaños Carla , Benítez Andrés
Published: October 2023

El objetivo de esta investigación es proponer una metodología de estimulación cognitiva que combine el idioma inglés y la música para mejorar la regulación conductual en niños diagnosticados con Trastorno de Déficit de Atención e Hiperactividad. La escolarización inclusiva y la atención a estudiantes con necesidades educativas específicas se ha convertido en una de las principales preocupaciones y desafíos que enfrentan los sistemas educativos, las instituciones, los docentes y la sociedad. Esta investigación es documental y descriptiva, emplea un enfoque deductivo-inductivo a través de una búsqueda bibliográfica, fortalecida por plataformas con artículos disponibles e información registrada con fichas nemotécnicas sobre la definición del trastorno, sus características y particularidades en los niños de la primera infancia; con el fin de generar una propuesta de abordaje utilizando la música y el inglés como segunda lengua. La información obtenida facilita la manera de estructurar teorías fundamentales sobre la incidencia de la música y el aprendizaje de otra lengua en el progreso cognitivo de niños con dicho trastorno. La plasticidad de la excitabilidad intrínseca de las neuronas puede desempeñar múltiples funciones esenciales en los procesos de aprendizaje y memoria. Por el contrario, las alteraciones en la excitabilidad intrínseca pueden influir en diversas patologías como el trastorno objeto de estudio y por sus diferentes manifestaciones.
Perspectivas de los emprendimientos en el cantón pastaza: retos y limitaciones
Authors: Paguay Córdova Alex Delfin , Cejas Martínez Magda
Published: October 2023

La investigación representa un tema primordial dentro del ámbito económico y social vinculado al desarrollo del Ecuador; en la actualidad, los emprendimientos se convierten en una alternativa de crecimiento significativo para el país en virtud de la necesidad de creación de negocios que sean innovadores y rentables. El objetivo de esta investigación es analizar las perspectivas de los emprendimientos para el desarrollo de los retos y la disminución de las limitaciones existentes en el cantón Pastaza Se pretende así mismo, evaluar las condiciones y factores que intervienen en el desarrollo de los emprendimientos: falta de empleo, ausencia de políticas públicas, recesión económica ocasionada por la pandemia, problemáticas sociales, entre otros. La metodología es de tipo descriptivo, considerando el estudio a través de un enfoque mixto, dado que, permite articular una investigación cuantitativa y cualitativa. Como muestra se ha considerado el estudio de emprendimientos correspondiente al Cantón Pastaza. Finalmente, se apunta a determinar los retos y limitaciones que enfrentan los emprendedores al momento de iniciar o continuar con su propuesta de negocio, cabe recalcar que, el hecho de la incidencia de una coyuntura inestable para el emprendedor. De igual forma, se destaca la importancia de la investigación en brindar un soporte y orientar hacia iniciativas idóneas en el marco del emprendimiento, generando un antecedente para los emprendedores, teniendo en cuenta los factores y ventajas competitivas en torno al objeto de estudio.
Influencia de factores sociodemográficos en la práctica de actividad física en adolescentes escolares de bachillerato de una institución educativa en la ciudad de Santiago de Cali – Colombia
Authors: Giraldo Acosta Daniel Felipe
Published: October 2023

Este artículo busca determinar la relación entre los factores sociodemográficos y la práctica de actividad física en adolescentes escolares de bachillerato en una institución educativa en la ciudad de Santiago de Cali-Colombia, teniendo la intención de investigar la razón por la cual los jóvenes pueden llevar un estilo de vida físicamente activo en comparación a otros, a pesar de que los estudiantes tienen el conocimiento de reconocer que el sedentarismo se asocia a la obesidad y las enfermedades no transmisibles. Para esto, se utilizó una metodología cuantitativa, de corte transversal y diseño descriptivo, realizado con una población de 550 estudiantes, de los cuales se utilizaron como muestra a 218 de ellos. Se aplicó como técnica los cuestionarios de recuento de actividad física. Y como instrumento de evaluación los cuestionarios APALQ (Assessment of Physical Activity Levels Questionnaire), KRECE-PLUS y una encuesta sociodemográfica. Resultados: se encontraron que existe una dependencia en las variables Sexo (p=0.035) y padres que realizan ejercicio (p=0.040) con el cuestionario APALQ. En la discusión, se identifica que el sexo femenino tiene 2.48 veces posibilidades de ser sedentarias que el sexo masculino debido a factores socioculturales y poco apoyo en deportes organizados; los hijos de padres que no realizan ejercicio tienen 2.4 veces probabilidades de ser sedentarios frente a los hijos de padres físicamente activos debido a factores de apoyo emocional y ánimo, siendo portadores de un influjo positivo o negativo; y los estudiantes clasificado por el KRECE-PLUS con bajo nivel de actividad física, son más propensos al sedentarismo.
KONSEP WASHATIYAH ISLAM PERSPEKTIF QURAISH SHIHAB (Telaah Kritik Nalar Islam Mohammed Arkoun)
Authors: Darman Muhammad Syawal Rosyid
Published: October 2023

Tindak ekstremis dengan menjadikan agama Islam sebagai alasan dibalik segala perbuatan menjadi hal yang sangat perlu diperhatikan. Sebab, Islam sendiri tidak memberikan kebenaran atas segala tindakan ekstremis. Quraish Shihab sebagai salah satu ulama kontemporer kerap kali memberikan pemahaman kepada masyarakat tentang wasathiyah (moderasi). Sebab Islam menginginkan agar umat muslim untuk selalu bersikap wasathiyah karena sikap wasathiyah adalah sikap yang diinginkan oleh Islam. Penelitian ini menggunakan teori kritik nlar Islam yang digagas oleh Mohammed Arkoun. Hal tersebut dilakukan agar kita dapat mengetahui metodologi tafsir yang digunakan oleh Quraish Shihab menggunakan metodologi yang berada di era mana. Tujuan penulisan ini untuk mengetahui konsep wasathiyah perspektif Quraish Shihab, mengetahui cirri-ciri dar perilaku ekstremis, dan mengetahui metode Quraish Shihab menurut the history of idea menggnakan metode era mana.  Metode yang digunakan dalam penuisan ini adalah metode kepustakaan (library research). Adapun tajapan penelitian yang dilakukan adalah dengan menghimpun sumber kepustakaan, baik primer maupun sekunder. Hasil dari penelitian ini, Menurut Quraish Shihab dari segi kebahasaan wasatiyah dapat juga dimaknai sebagai pertengahan dan adil. kan tetapi, kata tersebut belum sepenuhnya memberikan penjelasan tetang substansi dari makna wasathiyah. Sedangkan ekstremisme adalah tindakan yang dilakukan oleh seseorang atau kelompok yang telah melampaui batas terhadap norma, adat serta kebiasaan yang berlaku pada masyarakat, baik dengan menampilkan sesuatu yang bertentangan ataupun tidak. Kemudian, dari penelusuran terhadap penafsiran Quraish Shihab menggunakan kritik nalar Islam dari Arkoun, terdapat kesamaan walaupun tipis terkait sikap keterbukaan dalam menerima perspektif yang lain mengenai al-Qur’an.

Kata kunci: Quraish Shihab, Wasathiyah, Kritik Nalar Islam.
PENULISAN AL-QUR'AN BERAKSARA LATIN DAN PROBLEMATIKA PENERAPANNYA DI INDONESIA
Authors: Mumtaz Ali Zaky
Published: October 2023

Penelitian ini bertujuan untuk mengkaji polemik penulisan Al-Qur’an menggunakan aksara Latin dan bagaimana problematika penerapannya di Indonesia. Penulis menggunakan metode studi pustaka untuk mengkaji tema penelitian ini, melakukan penelaahan dan membuat kesimpulan serta menawarkan solusi problematika yang dihadapi masyarakat muslim Indonesia terkait tema penelitian ini. Dari kajian ini ditemukan bahwa penulisan Al-Qur’an menggunakan aksara Latin diperbolehkan selagi bisa mengakomodir kesesuaian pelafalan Al-Qur’an sesuai kaidah bahasa Arab. Oleh karena itu diperlukan konsensus standarisasi penulisan Al-Qur’an dalam bahasa Latin yang mudah untuk dipahami dan diterapkan masyarakat muslim Indonesia. Selain itu, tentunya pemberantasan buta aksara Arab bagi umat muslim Indonesia menjadi solusi utama sehingga Al-Qur’an bisa dibaca melalui aksara aslinya oleh semua kalangan umat muslim Indonesia tanpa melalui alih aksara.
QAIDAH USUL FI QIRA'AT IMAM NAFI’
Authors: Abdur Rohman Ali
Published: October 2023

Salah  satu  pembahasan  penting  dalam  kajian  al-Qur’an  adalah  tentang  qir?at al-Qur’an yang didalamnya membahas mazhab cara baca al-Qur’an dan yang melingkupinya.   Ragam   qir?at al-Qur’an   muncul   sejak   zaman   Nabi   sebagai kemurahan dari Allah SWT agar masyarakat pada waktu itu lebih mudah dalam membaca dan menghafal al-Qur’an.   Ragam qir?at al-Qur’an yang telah dianggap mutawatir  secara  ijma’  ulama  terdapat  tujuh  Im?m  qir?at yang  dikenal  dengan qir?at sab’ah.  Qir?at tersebut memiliki  ciri  khas  dan  cara  baca  masing-masing sehingga umat Islam hanya diwajibkan untuk memilih salah satu untuk pelaksanaan  ibadahnya.  Salah  satu  ragam  qir?at yang  terkenal  di  dunia  Islam adalah qir?at Im?m N?fi’ yang diriwayatkan oleh dua muridnya yang terkenal yaitu  Q?l?n dan  Warsy.  Meskipun  sama-sama  meriwayatkan  qir?at dari  Im?m N?fi, ada ketentuan baca yang berbeda di antara keduanya. Melalui kajian literatur, artikel ini berusaha mendiskripsikan kaidah baca dari masing-masing r?wi qir?at Im?m N?fi’ yaitu Q?l?n dan Warsy tersebut. Dari penelitian ini penulis menemukan  beberapa  titik  perbedaan  cara  baca  antara  Q?l?n dan  Warsy,  yaitu pada bab madd, cara baca lafadz ???  yang bertemu dengan hamzah qa?a’, ?ilah, mim, jama’, bacaan l?m, dan im?lah-taql?l.
ANALISIS SEMANTIK TOSHIHIKO IZUTSU PADA LAFADZ AL-HUBB DALAM AL-QUR’AN
Authors: Mumtazah Niha Barrah , Arifin Ali Zaenal , Suwarno Suwarno
Published: October 2023

Artikel ini berisi mengenai analisis semantik pada lafaz hubb dalam Al-Qur’an. Cinta merupakan fitrah hidup manusia, setiap manusia dilahirkan dengan mempunyai perasaan cinta. Baik itu berupa cinta dari aspek biologis, sosial maupun teologis. Di dalam Al-Quran banyak ayat yang menyebutkan tentang cinta tetapi setiap perkataan cinta yang disebutkan di dalam sesuatu ayat tidak membawa konsep makna yang sama. Hal ini karena, setiap perkataan cinta tersebut membawa makna yang berbeda mengikut zaman atau masa yang berlaku dalam sebuah ayat Al-Quran itu. Kajian ini dilakukan untuk menjawab persoalan mengenai konsep cinta pada lafaz al-hubb yang terkandung di dalam Al-Quran. Kajian ini dilakukan dengan pendekatan kualitatif yaitu menghimpunkan data, memperoleh makna serta pemahaman sesuatu topik dengan sumber primer. Penelitian ini menggunakan pendekatan semantik Toshihiko Izutsu. Dalam pendekatan ini ada tiga fokus utama yang akan diteliti, pertama yaitu makna dasar dan makna relasional yang meliputi sintagmatik dan paradigmatik, pra-Qur’anik, Qur’anik dan pasca Qur’anik dan ketiga yaitu weltanschauung.
“AL-KHASYAH” DALAM AL-QUR’AN
Authors: Ali Zaky Mumtaz , Pertiwi Anggi Amelia
Published: October 2023

Penelitian ini hadir untuk menganalisis ayat-ayat mengenai Al-Khosyah dan bagaimana penerapannya pada kehidupan modern. Agar pembaca bisa memahami rasa takut yang seperti apa yang seharsnya dimiliki oleh hamba kepada Tuhannya. Penelitian ini merupakan penelitian kepustakaan (Library Research). Dengan menggunakan metode kajian tematik. Teknik pengumpulan data dilakukan dengan mengumpulkan ayat-ayat yang bermakna “Takut” pada tafsir Al-Khaw??ir ?aula Al-Qur’?n Al-Kar?m. Dan  menganalisis penafsiran Imam Al-Sya’r?w? dalam kitab tafsir Al-Khaw??ir ?aula Al-Qur’?n Al-Kar?m. Dan menganalisis bagaimana implementasinya bagi masyarakat modern. Kesimpulan dari penelitian ini adalah Al-Khasyah merupakan rasa takut yang disertai dengan pengagungan dan penghormatan kepada objek yang ditakuti. Ciri-ciri dari orang yang memiliki al-Khasyah adalah pertama, senantiasa merasa diawasi Allah. Kedua, beramal semata-mata hanya hanya untuk Allah  dan selalu menghisab dirinya. Ketiga, ketika dia melihat pada dirinya terdapat sesuatu yang menyimpang dengan firman Allah, dan ia mengingat ancaman Tuhannya. Maka akan bergetar kulitnya disebabkan oleh rasa takut kepada Tuhannya. Cara mengimplementasikan al-Khasyah adalah Mentadabburi Ayat-Ayat Kauniyyah, mempelajari Ilmu-Ilmu yang Membuat Semakin Mengenali Allah, senantiasa Merasa Diawasi Allah, berinf?q di Jalan Allah, memperbanyak Berdzikir kepada Allah. Faidah dari memiliki al-Khasyah adalah mendapatkan ampunan dan balasan yang besar, berhati-hati terhadap hari kiamat, masuk ke dalam Surga, mudah untuk menerima peringatan dan hidayah, dan mendapatkan keridhoan Allah.
As a good prognostic sign, Autosplenectomy is higher in females in Sickle Cell Diseases
Authors: Helvaci Mehmet Rami , Pappel Valeria , Piral Kubra , Ozer Selim , Camlibel Mehpar , Sencan Huseyin , Davran Ramazan , Abyad Abdulrazak , Pocock Lesley
Published: October 2023

Background: Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries. Methods: All patients with the SCDs were included. Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Although the higher prevalence of autosplenectomy (50.4% vs 53.3%, p<0.05), transfused units of red blood cells (RBCs) in their lives (48.1 vs 28.5, p=0.000), disseminated teeth losses (5.4% vs 1.4%, p<0.001), ileus (7.2% vs 1.4%, p<0.001), cirrhosis (8.1% vs 1.8%, p<0.001), leg ulcers (19.8% vs 7.0%, p<0.001), clubbing (14.8% vs 6.6%, p<0.001), coronary heart disease (CHD) (18.0% vs 13.2%, p<0.05), chronic renal disease (CRD) (9.9% vs 6.1%, p<0.05), chronic obstructive pulmonary disease (COPD) (25.2% vs 7.0%, p<0.001), and stroke (12.1% vs 7.5%, p<0.05) were all lower in females. Conclusion: The sickled or just hardened RBCs-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood. Although RBCs suspensions and corticosteroids in acute, and aspirin with an anti-inflammatory dose plus low-dose warfarin plus hydroxyurea both in acute and chronic phases decrease severity, survivals are still shortened in both genders, dramatically. Although the higher prevalence of autosplenectomy, transfused units of RBCs in their lives disseminated teeth losses, ileus, cirrhosis, leg ulcers, clubbing, CHD, CRD, COPD, and stroke were all lower in females. So there may be an inverse relationship between autosplenectomy and severity of SCDs, and spleen may act as a chronic inflammatory focus as a filter of blood for these sickled or just hardened RBCs. Key words: Sickled or just hardened red blood cells, capillary endothelial edema, myocardial infarction, stroke, sudden deaths, autosplenectomy, female gender
Metabolic Control and Its Correlates among Diabetic Patients in Aljouf Region, Saudi Arabia: A Cross-Sectional study
Authors: Mohamed Rehab A , Abdel-Salam Doaa Mazen , Galal Heba M. , Alsahli Ohoud Mohammed F , Althari Alhanof Ahmed , Alorayyidh Batool Meshal , ALHarbi Reema Hamad A , Almohammed Zainab Mohammed M
Published: October 2023

Background: Throughout the world, diabetes, and its consequences, constitutes a serious problem for public health. Metabolic control can reduce the risk of diabetes complications. The present study aims to determine diabetic metabolic control among diabetic patients in the Aljouf region, Saudi Arabia, and its association with family function, depression, and other sociodemographic and clinical data. Methods: A cross-sectional study was conducted among 279 diabetic patients attending the diabetic center in a specialized hospital in Aljouf Region, Saudi Arabia. A structured anonymous questionnaire was distributed to the targeted population during a direct interview. Results: The present study showed that HbA1c was 7% among 86% of the participants. Regarding lipid profile, abnormal HDL, LDL, triglycerides, and cholesterol levels were detected among 39.4%, 41.2%, 68.5%, and 50.2% of the participants, respectively. Severe depression and severe family dysfunction were detected among 22% and 6% of the participants, respectively. Increasing age was associated with higher LDL levels and diabetes duration was associated with higher HbA1c levels in patients with diabetes. Conclusion: The study concluded that family function and depression do not directly affect diabetic patients’ diabetes metabolic control and the study showed a high prevalence of uncontrolled HbA1c levels and dyslipidemia among the study participants. Further investigation into the variables underlying the control of diabetes is required to further enhance patient outcomes because many people are still failing to meet the metabolic control objectives. Keywords: Metabolic control; Depression; Family function; Diabetes mellitus; Saudi Arabia
A systematic review of interventions to improve medication adherence in family medicine patients
Authors: Alrashidi Abdullah Salih , Alasmari Hassan Dhafer Hassan , Alshammari Abdulaziz Muteb , Alrashedi Khaled Saleh
Published: October 2023

Background: Medication non-adherence poses a significant challenge in healthcare, leading to suboptimal treatment outcomes. This systematic review aims to evaluate the effectiveness of different interventions in improving medication adherence. Methodology: A comprehensive search was conducted to identify relevant studies. Inclusion criteria encompassed interventions targeting medication adherence and reporting quantitative measures of adherence outcomes. The selected studies were assessed for quality, and data were extracted for analysis. Results: The review included a total of 14 studies. Interventions involving tailored phone calls or educational materials did not yield significant improvements in medication adherence. Conversely, interventions such as face-to-face counseling sessions and self-management programs showed promise in improving adherence. Nurse-led interventions and pharmacist-led consultations did not demonstrate significant improvements. Similarly, interventions involving stroke physician specialist assessments, behavioral feedback, medication reviews, and motivational interviewing did not yield significant improvements. A pooled analysis of various interventions across different healthcare settings showed a moderate but not statistically significant difference in medication adherence. Conclusion: The findings from this systematic review suggest that interventions tailored to individual patient characteristics and involving personalized support and education show promise in improving medication adherence. However, interventions relying solely on tailored phone calls, educational materials, nurse-led care, pharmacist-led consultations, stroke physician specialist assessments, behavioral feedback, medication reviews, or motivational interviewing may not consistently improve adherence. Keywords: Medication Adherence, Patient Compliance, Family Medicine, Education, Behavioral Modification.
Diabetic Ketoacidosis After COVID-19 Vaccine in Patients with Type 1 Diabetes Mellitus
Authors: Albedaiwi Fahad Bedaiwi , Alshammari Manar , Algeffari Metab , Alfouzan Abdulmajeed , Alfouzan Yasmeen , Siddiq Hassan , Hussein Omaima
Published: October 2023

Background: The coronavirus disease 2019 (COVID-19) vaccine is one of the few vaccines that obtained emergency authorization to combat the fatal pandemic. Despite the fact that some available literature addressed its short-term side effects, there are still limitations on its effects on type 1 diabetes mellitus (T1DM). Objectives: The aim of the present study was to assess the association between COVID-19 vaccination and diabetic ketoacidosis (DKA) among individuals with T1DM. Additionally, the study aimed to determine the effects of the vaccine on glucose control, variability, and risk of hypoglycemia. Methods: This retrospective study was conducted at King Fahad Specialist Hospital (KFSH) in Qassim Region, Saudi Arabia. Diabetic ketoacidosis cases admitted to the hospital within February 2020 and August 2022 were included in the study based on specific inclusion criteria. Finally, a total of 49 patients were included in statistical analyses. Results: Out of the 62 patients admitted to the hospital, 49 met the diagnostic criteria for DKA and agreed to participate in the study. The majority of the remaining patients (n = 13) refused to participate, and only a few of them lacked complete documentation. Of the 49 patients who were included in the study, 46 cases had a history of T1DM; nevertheless, 3 patients were newly diagnosed with T1DM. Additionally, among these participants, 16 (32.7%), 19 (38.8%), and 14 (28.6%) patients had mild, moderate, and severe DKA, respectively. There were 27 male (55.1%) and 22 female (44.9%) patients. About 91% of the patients were vaccinated against COVID-19, 30.6% of whom were vaccinated within 29 days of being diagnosed with DKA. The pH and bicarbonate levels were observed to be significantly high among those who were diagnosed with DKA within 29 days of vaccination, with p-values of 0.031 and 0.037, respectively. Similarly, pH and random blood sugar (RBS) were observed to be significantly higher among the vaccinated patients than in the non-vaccinated subjects (P = 0.044 and P = 0.032, respectively). Conclusions: The study findings revealed that some of the DKA indicators were evident among the vaccinated patients. However, larger-scale and multi-center studies are recommended in order to have more conclusive evidence and generalize the findings.
Novel Compound Heterozygous Mutations of the SLC12A3 Gene in Gitelman Syndrome with Growth Hormone Deficiency and Hypothyroidism
Authors: Ma Yaping , Xu Zhuangjian
Published: October 2023

Introduction: Gitelman syndrome (GS) is an inherited kidney disease that causes an imbalance of charged ions in the body. SLC12A3 mutation is the predominant cause of GS. There are different known and unknown pathogenic mutations in SLC12A3. Case Presentation: In the present case report, an 8-year-old girl was referred to our pediatric endocrinology clinic for evaluation of short stature. Her height was 113 cm (-2.94 SD). Her growth hormone peak was 5.81 ng/mL. IGF-1 was lower than -2SD. Thyroid stimulating hormone was high. The blood potassium was 3.37 mmol/L. After 3 months of GH treatment, her blood potassium dropped further (3.01 mmol/L). The gene test results showed that there were two heterozygous mutations of the SLC12A3 gene: C.1456G>A (p.D486N) and c.1065_1072 delGCAGGG (p.A356Qfs*5), which her parents verified. Conclusions: Gitelman syndrome can be associated with growth hormone deficiency and hypothyroidism in addition to short stature, hypokalemia, and hypomagnesemia, and the underlying molecular mechanisms need to be explored in the coexistence of these three diseases. The experience, in this case, is that blood electrolytes should be checked monthly for the first three months after growth hormone treatment for short stature. Once the blood potassium level is low, much attention should be paid to further diagnosis to avoid misdiagnosis.
Urtica dioica (Nettle) in Type 1 Diabetes Mellitus: A Randomized Controlled Trial
Authors: Shahrokhi Maryam , Koohmanaee Shahin , Haghghi Reyhaneh , Hassanzadeh Rad Afagh , Esfandiari Mohammad Ali , Parvinroo Shirin , Dalili Setila
Published: October 2023

Background: As the role of nettle supplementation for type 1 diabetic patients is still unclear, we aimed to evaluate the impact of nettle supplementation on children with type 1 diabetes mellitus. Methods: In this single-blind randomized controlled trial, 50 patients with type one diabetes aged 12 - 18 with improper glycemic parameters (HbA1c greater than 6.5 mg/dL) received either insulin with 5 cc of nettle syrup (i.e., quercetin-based on at least 0.04 mg/mL of chlorogenic acid) twice daily for 12 weeks, or insulin monotherapy. Demographic characteristics, fasting blood sugar, HbA1c, blood urea nitrogen (BUN), serum creatinine, and insulin dosage were investigated at the beginning of the study and at multiple intervals in both groups. Results: Changes in fasting blood sugar (FBS), HbA1c, mean dose of rapid-acting and long-acting insulin, and mean total insulin dose were significant in both groups, and the increase in total insulin dose was significantly lower in the intervention group (P < 0.05). The trend of BUN and serum creatinine changes was not significant over time (P = 0.532 and P = 0.785, respectively). Conclusions: We found lower total insulin dose in the intervention group that may emphasize the positive effect of nettle concomitant use through insulin secretion or sensitizing effect.
Serum Omentin-1 Levels in Obese Adolescents with Vitamin D Deficiency: A Prospective Cross-sectional Study
Authors: Erol Meltem , Karan Fatih , Ozel Abdulrahman , Bostan Gayret Ozlem , Zengi Oguzhan
Published: October 2023

Background: Vitamin D deficiency is common in obese adolescents. It modulates the release of omentin 1 from adipose tissue. We believe that both vitamin D and omentin 1 affect each other in adipose tissue via inflammation. Objectives: This study aimed to examine serum omentin-1 levels in obese adolescents with vitamin D (Vit D) deficiency. Methods: In this cross-sectional prospective study, 83 obese adolescents were included. Serum 25-hydroxy vitamin D (25(OH)D) concentrations, fasting glucose, and lipid profiles of obese adolescents were studied. At the same time, blood was drawn into a separate tube to study the omentin 1 level. Of the 83 obese cases, 45 with 25(OH)D concentrations below 20 ng/mL were considered as the study group, and 38 with 25(OH)D concentrations ≥ 20 ng/mL as the control group. Serum omentin-1 levels were evaluated and compared. Results: The average 25(OH)D value in the study and control groups was 17.14 ± 2.22 ng/mL and 45.29 ± 24.98 ng/mL, respectively. The average omentin-1 concentration of the control group was 262.5 ± 136.31 ng/mL, and the mean omentin-1 level of the study group was 113.23 ± 15.98 ng/mL. The mean omentin-1 concentrations of the study group were significantly lower compared to the control group (P = 0.0001). There was a significant and positive correlation between omentin-1 and 25(OH)D (r = 0.988, P = 0.0001). In univariate tests, linear regression analysis was carried out with 25(OH)D and omentin-1, and 25(OH)D displayed a significant positive correlation (P = 0.0001). The optimal cut-off point for the serum omentin-1 concentration was 135.01 ng/mL. No significant correlation was determined between omentin-1 and body mass index, lipid profile, glucose, and insulin variables (P > 0.05). Conclusions: We showed significantly low concentrations of serum omentin-1 in obese adolescents with vitamin D deficiency. Serum omentin-1 can be employed as a biomarker in obese adolescents with vitamin D deficiency.
Granulocyte Colony-Stimulating Factor (G-CSF): Is It Effective for Feeding Tolerance in Very Low Birth Weight Infants?
Authors: Akbarian Rad Zahra , Farahanian Elham , Ahmadpour-Kacho Mousa , Zahedpasha Yadollah , Khafri Soraya , Valizadeh-Chari Zahra , Haghshenas Mojaveri Mohsen
Published: October 2023

Background: Feeding intolerance is one of the most common problems in very low birth weight infants. Granulocyte colony-stimulating factor (G-CSF), one of the cytokines in amniotic fluid and human milk, plays an important role in gut maturation. Objectives: The aim of this study was to evaluate the effect of oral administration of G-CSF on feeding tolerance in preterm infants weighing ≤ 1200 g. Methods: This randomized, single-blind, placebo-controlled clinical study was conducted between September 2018 and June 2019 on preterm infants (≤ 32 weeks) weighing ≤ 1200 g and matched in terms of gestational age, birth weight, and umbilical cord pH. The intervention group received G-CSF by gavage simultaneously with the start of enteral feeding stopped after 10 days. The primary outcome was the duration of infant milk that reached 50, 75, and 100 mL/kg/day, and the secondary outcomes were the onset of weight gain and the length of hospital stay. Results: Out of 68 eligible infants, 31 infants in each group completed the study. There was no significant difference between the two groups in terms of the length of hospital stay and the duration of reaching a feeding volume of 50 and 75 mL/kg/day; nonetheless, the duration of reaching a feeding volume of 100 mL/kg/day and the time to start gaining weight in the case group were significantly shorter than those of the control group (P = 0.029 and P = 0.002, respectively). Conclusions: The oral administration of G-CSF in preterm infants ≤ 1200 g improves feeding tolerance and can further shorten the time to reach full enteral feeding.
Effects of Plyometric Training on Lower Limb Strength and Power in Young Postpubertal High Level Basketball Players
Authors: Gadea Uribarri Hector , Mainer Pardos Elena , Villanueva Guerrero Oscar , Caro Serrano Alvaro , Gonzalo Skok Oliver , Roso-Moliner Alberto , Lozano Demetrio
Published: October 2023

Background: Currently, the scientific evidence available on plyometric training in young basketball players is limited. Objectives: The aim of this study was to analyze the effects produced by plyometric training over a period of 8 weeks, with a frequency of two weekly training sessions, combining vertical and horizontal force vectors. Methods: The study involved 28 young men (14.54 ± 0.6 years, a height of 182.76 ± 7.1 cm and a body weight of 68.05 ± 9.8 kg) high-level basketball players and aimed to investigate the effects of this training program on athletes at different maturational states, specifically based on their peak height velocity (PHV) and post-pubertal (post-PHV) stages. Results: Substantial improvements were achieved in the subjects who have carried out this type of plyometric training in all the parameters evaluated related to the improvement of the jump, linear speed and change of direction. Conclusions: Therefore, it is crucial to provide valuable information to trainers and physical trainers, enabling them to improve and individualize the conditioning work for optimal performance of their athletes.
Catastrophic Health Expenditure and Out-of-pocket Payments for Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG)
Authors: Ghahramani Sulmaz , Rastegar Kazerooni AmirAli , Hasannia Sedigheh , Sayari Mohammad , Rastegar Kazerooni Amir Hossein , Bagheri Lankarani Kamran
Published: October 2023

Background: When households have high out-of-pocket (OOP) expenses, they are more likely to experience poverty and encounter catastrophic health expenditures (CHE). Heart disease is a significant cause of health decline and mortality. Objectives: This study aimed to provide essential knowledge about CHE and OOP for heart disease patients who underwent coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) in Shiraz, Iran. Methods: This cross-sectional study with two prospective follow-ups was conducted in three heart surgery centers in Shiraz, Iran. The data were collected using the world health survey (WHS). Catastrophic health expenditures and OOP were asked from the most informed family member. Generalized estimating equation (GEE) modeling was employed to identify the main factors related to CHE and OOP. Binary distribution with logit link and gamma distribution with log link were used for CHE and OOP, respectively. The significance level was set at 0.05. Results: We found that OOP payment among patients who needed cardiovascular services in public-private partnership (PPP) hospitals was 76,953,100 Rials (R), equal to 2,506.78 $ (USD) (SD = 53,247,600 R/1,734.56 $) in the PCI group and 230,937,700 R equal to 7,522.89 $ (SD = 248,295,200 R/8,088.32 $) in the CABG group. This value in public hospitals was 15,083,800 R, equal to 491.36 $ (SD = 18,637,600 R/ 607.13 $) in the PCI group and 12,276,800 R, equal to 399.92 $ (SD = 11,131,900 R/ 362.63 $) in the CABG group. We also found that admission duration, age, type of hospital, and being currently a smoker were significant factors for OOP (P-value < 0.05). During baseline assessment, we also found that the percentage of PCI patients that faced CHE was 95.56% and 47.92% in PPP and public hospitals, respectively. This value in CABG patients was 92.31% and 40.45%. Our study showed that the type of hospital and socioeconomic status were significant factors (P-value < 0.05) that pushed a family facing CHE. Conclusions: The baseline CHE is very high in both PCI and CABG patients. Thus, the government should pay special attention to this issue. Further investigations are needed on factors affecting OOP and CHE.
Improving Natural Resistance to Cancer: An Overview of Metabolic Pathways in Cancer Cells Integrated with Regional Cancer Incidence Statistics
Authors: Bahrami Hassan , Tafrihi Majid
Published: October 2023

Context: Cellular metabolism is a set of controlled biochemical reactions known as metabolic pathways that occur in living organisms in order to sustain life. Cells may use different metabolic pathways and alter metabolism to use more effective processes for survival depending on cellular conditions. Alterations in metabolic pathways can lead to the transformation of normal cells into cancerous cells, leading to cancer initiation and development. Objectives: Proper cellular conditions in terms of pH and the availability of essential nutrients and oxygen are important for the healthy functioning of aerobically respiring human cells. If cells are exposed to stressors such as carcinogens that can induce mutations in the genes involved in metabolic pathways, anaerobic metabolism may be used by cells, turning them into cancerous cells. Cellular conditions that maintain aerobic cellular respiration and mitigate the effects of cellular stressors can improve cells’ resistance to neoplastic transformation. Methods: This paper explores the key metabolic pathways used by cancer cells as a function of their environmental conditions based on the Warburg effect. In addition, some analyses and studies were conducted on global and regional cancer incidence rates, taking into account changes in lifestyle and dietary patterns. Results and Conclusions: Natural resistance to cancer may be improved when cells grow in healthy conditions at molecular levels, requiring a balanced alkalizing diet and healthy lifestyle, as well as reduced exposure to environmental carcinogens, which are key control factors. In particular, effective nutritional interventions can help normal cells resist metabolic changes underlying cancer development.