bluuebunny/crossref_metadata_2025 huggingface dataset:
A Qualitative Study of the Effect of Public Participation on Stunting Prevention Behavior in Pandeglang Regency
Authors: Sinaga Frida Rismauli , Sidin Fasbhir H.M. Noor , Jalal Fasli , Fatmawati Fatmawati , Hardisman Hardisman
Published: May 2023

BACKGROUND: Stunting is a major nutritional problem facing Indonesia. Stunting has the highest prevalence compared to other nutritional problems such as malnutrition, underweight and obesity.
MATERIAL AND METHODS: This study use a mix method approach. Qualitative research data analysis was carried out by triangulation.
RESULT: The results showed that direct effect on stunting prevention was 45% motivation and the indirect effect was the stunting prevention policy of 42.61%.
CONCLUSION: In this study it was concluded that the implementation of increasing public participation is expected to increase stunting prevention behavior in the public, especially in the Pandeglang Regency area.
Keywords: Stunting, Public participation, Public behavior
Analysis of Factor Influencing Delayed Referral of Undescended Testis
Authors: Janardhana Alfryan , Daryanto Besut , Gumilar Ogi Bahaurini
Published: May 2023

BACKGROUND: The rate of delay in the referral of patients with undescended testis (UDT) to health facilities in Indonesia is still relatively high due to delays in the handling of urological surgery. Hence, it requires rapid and appropriate identification and early detection of patients with UDT in the community.
AIM: The study aims to analyze the factors of delay in referral in cases of UDT management.
METHODS: This study used a cohort design with a retrospective review approach to analyze various factors that cause delays in referring patients with UDT. Collecting identification was done by tracing UDT case-patient documents from January 2016 to November 2021. Data analysis used the Mann–Whitney and Chi-square comparison test, with significance achieved if the p < 0.05.
RESULTS: Delay by doctors/paramedics who were not followed up, ignorance of the risk of delaying surgery, and undiagnosed UDT by parents/health-care providers showed a significant difference where the percentage of patients who were delayed was greater on these factors. In addition, the reference source is also known to have a significant difference with a significant value (p < 0.005).
CONCLUSIONS: Factors that played a significant role in the delay in operative procedures for treating UDT were delays in referral from doctors (p < 0.025) (primary care physicians and pediatricians) and undiagnosed UDT conditions in patients (< 0.005).
Lighting of the Working Space
Authors: Radevski Aleksandar , Karanakov Bojan , Papasterevski Dimitar
Published: May 2023

The primary subject of this research is defining the workspace through the impact of light and the size of openings through which light penetrates. In that sense, workplace is taken as a model that is researched and analyzed from the aspect of geometry and proportion. The workplace, being an elementary space in which human’s act, represents space which is continuously resided in for thelongest period of time throughout the day. For that reason, the natural light penetrating through the light openings, as well as the view from them on the outside world, is a crucial factor for the quality of space.
Paravalvular Abscess of the Mechanical Prosthetic Aortic Valve: A Case Report
Authors: Mackic Denis , Custovic Faruk , Begic Edin
Published: May 2023

BACKGROUND: Prosthetic mechanical valve endocarditis (PVE) can be manifested as early PVE (acquired perioperatively) and late PVE (resulting from infections unrelated to the valve operation). Causes of both are similar but are late PVE are more prone to less virulent microbes. PVE resulting with paravalvular abscess is confirmed through echocardiography (transthoracic or transesophageal), it results with a high mortality rate especially if it is not early recognized. The aim of article was to present a patient with heart failure symptoms caused by PVE.
CASE PRESENTATION: Male patient, 44 years old, was admitted because of dyspnea and swelling of lower extremities. The patient is a long-standing heroin addict who had aortic valve replacement done 8 years ago due to endocarditis. The implanted valve was a mechanical aortic valve – Edwards MIRA bi-leaflet valve No 32 (Edwards Lifesciences; Irvine, California). He also was already diagnosed with hepatitis C years before. In multiple occasions were hospitalized on the Department of cardiology due to signs and symptoms of heart failure. On transthoracic echocardiography, dilatation of all heart chambers was found. The left ventricular systolic function was moderately reduced with an ejection fraction of left ventricle of 42% according to Simpson with restrictive filling pattern. Hypoechoic mass along the right side of the mechanical aortic valve was noted measuring 3.57 × 1.03 cm.
CONCLUSION: Paravalvular abscess of mechanical heart valves is a very serious complication with a high mortality rate. It is essential to recognize this type of pathology as early as possible, so aggressive parenteral antibiotic therapy could be started, while in many cases, surgical reoperation is needed.
Papillary Muscle Rupture as a Complication of Barlow’s Disease
Authors: Kuzmanoski Ile , Georgieva Aleksandra , Chelikikj Ana , Andova Valentina
Published: May 2023

INTRODUCTION: Mitral regurgitation (MR) is the second most common valvulopathy worldwide, which can be divided into primary and secondary. According to Carpentier’s classification, the primary MR is further divided into three types. Type II, which includes Barlow’s disease, is described as excessive mobility of the mitral valve (MV) leaflets. Morbus Barlow is a common form of degenerative disease, with an incidence of 2–3% of the general population. Echocardiography plays an important role in its diagnosis. It is a usually benign condition, with only a few severe complications. CASE REPORT: A 75-year-old male with a history of MR, for more than 10 years. On admission, the patient presented with severe fatigue and dyspnea with signs of heart failure and pleural effusion. On auscultation, a systolic murmur was noted, on all the precordium. The ECG revealed sinus rhythm with HR of 71/min and intermittent ventricular extrasystoles. An immediate transthoracic echocardiography (TTE) was performed showing myxomatous degeneration of both MV leaflets and a prolapse of the posterior leaflet. A severe MR was detected with a presumption of papillary muscle rupture (PMR). It also revealed enlarged left atrium and ventricle (LVEDd - 67 mm and LA - 46 mm), with preserved systolic function (EF~54%) and tricuspid regurgitation accompanied by pulmonary hypertension. The laboratory analyses were within normal ranges. The patient was transferred to a cardiovascular surgery clinic, where an immediate MV repair was performed. CONCLUSION: Barlow’s disease is a common echocardiography finding. Although a benign condition, it can rarely present with serious complications such as PMR, ventricular arrhythmias, and even sudden cardiac death. Echocardiography is the first imaging used for the detection of Barlow’s disease and other MV diseases. Early recognition and confirmation with TTE or transesophageal echocardiography, plays also an appropriate treatment, play a key role in patient survival and overall prognosis.
Peripartum Cardiomyopathy Due to Gestational Hypertension and Tocolytic Therapy
Authors: Chelikikj Ana , Jovanova Silvana , Grueva-Nastevska Elena , Kandic Elma , Kuzmanoski Ile , Bushljetikj Oliver , Zimbakov Zhan
Published: May 2023

BACKGROUND: Peripartum cardiomyopathy (PPCM) is a rare and sometimes fatal systolic heart failure that affects women during late pregnancy or the early postpartum period. The risk factors contributing to this condition are advanced maternal age, multiparity, administration of tocolytic agents, underlying cardiac disease, iatrogenic volume overload, preeclampsia, and hypertension. In patients with gestational hypertension (GH) and other risk factors, close monitoring is mandatory during pregnancy as well as in the postpartum period.
CASE REPORT: A 38-year-old patient previously treated for endometriosis, infertility, and GH was transferred from the clinic of gynecology due to diagnosed congestive heart failure. 5 days before admission, she gave birth to her first child. Before delivery, she was treated with tocolytic therapy. She received methyldopa due to GH which was abruptly discontinued after her delivery. Echocardiography on admission revealed moderately reduced left ventricular (LV) systolic function with an ejection fraction (EF) of 37% with dilated left ventricle (LV) and pulmonary artery hypertension secondary to LV failure. During hospitalization, the patient was with signs of volume overload, but with a good response on parenteral diuretic therapy. She was additionally treated with guideline-recommended heart failure therapy. The controlled echocardiography showed improvement of LV function with an EF of 42%.
CONCLUSION: PPCM is a rare condition with high morbidity and mortality. An LVEF <30%, marked LV dilatation, LV end-diastolic diameter >6.0 cm, and RV involvement are associated with adverse outcomes. Although delivery of the fetus and the placenta triggers the resolution of symptoms and recovery to the nonpregnant state of various organisms, the contrary happens with blood pressure. Its peak time is 3–6 days after delivery. Hypertension medication must not be immediately terminated. Prolonged tocolytic therapy is a risk factor for PPCM due to causing decreased baroreflex sensitivity. Patients with risk factors should be closely monitored for eventual cardiac complications.
Argonaute, Vault, and Ribosomal Proteins Targeted by Autoantibodies in Systemic Lupus Erythematosus
Authors: Moadab Fatemeh , Wang Xiaoxing , Najjar Rayan , Ukadike Kennedy C. , Hu Shaohui , Hulett Tyler , Bengtsson Anders A. , Lood Christian , Mustelin Tomas
Published: May 2023

Objective

To expand, in an unbiased manner, our knowledge of autoantigens and autoantibodies in patients with systemic lupus erythematosus (SLE) and evaluate their associations with serological and clinical variables.

Methods

Human proteome arrays (> 21,000 proteins) were screened with serum from patients with SLE (n = 12) and healthy controls (n = 6) for IgG and IgA binding. Top hits were validated with 2 cohorts of patients with SLE (cohort 1, n = 49; cohort 2, n = 46) and other rheumatic diseases by ELISA. Clinical associations of the autoantibodies were tested.

Results

Ro60 was the top hit in the screen, and the 10 following proteins included 2 additional known SLE autoantigens plus 8 novel autoantigens involved in microRNA processing (Argonaute protein 1 [AGO1], AGO2, and AGO3), ribosomes (ribosomal protein lateral stalk subunit P2 and ovarian tumor deubiquitinase 5 [OTUD5]), RNA transport by the vault (major vault protein), and the immune proteasome (proteasome activator complex subunit 3). Patient serum contained IgG reactive with these proteins and IgA against the AGO proteins. Using the 95th percentile of healthy donor reactivity, 5-43% were positive for the novel antigens, with OTUD5 and AGO1 showing the highest percentages of positivity. Autoantibodies against AGO1 proteins were more prevalent in patients with oral ulcers in a statistically significant manner. IgG autoantibodies against AGO proteins were also seen in other rheumatic diseases.

Conclusion

We discovered new autoantigens existing in cytosolic macromolecular protein assemblies containing RNA (except the proteasome) in cells. A more comprehensive list of autoantigens will allow for a better analysis of how proteins are targeted by the autoimmune response. Future research will also reveal whether specific autoantibodies have utility in the diagnosis or management of SLE.
Surgical Management of Failed Articular Cartilage Surgery in the Knee
Authors: Campbell Michael P. , Sonnier John Hayden , Wright Margaret L. , Freedman Kevin B.
Published: May 2023

Failure rates of cartilage restoration surgery range from 14% to 43%. When failure of prior cartilage restoration surgery is suspected, a thorough clinical workup should be performed to assess the timing and duration of symptoms. Attention should be paid to patient risk factors such as age, body mass index, and smoking status. Concomitant pathology such as malalignment, ligament insufficiency, and meniscus status must be evaluated before revision surgery. As outlined in our treatment algorithm, the size/location of the lesion and the type of primary procedure will guide planning for revision procedures. [
Orthopedics
. 2023;46(5):262–272.]
Multicentric Giant Cell Tumor of Bone
Authors: Errani Costantino , Tsukamoto Shinji , Angulo Alvarado Rebeca , Righi Alberto , Nitta Yuji , Donati Davide Maria , Mavrogenis Andreas F.
Published: May 2023

The typical presentation of giant cell tumor of bone is a solitary lesion involving the meta-epiphyseal region of the long bones. The presence of more than one distinct giant cell tumor in the same patient is rare. This study reports on 7 patients with multicentric giant cell tumor of bone. Clinical and radiologic features were reviewed to evaluate the behavior of multicentric giant cell tumor of bone. Immunohistochemistry and genetic analysis for the H3F3A gene were performed to confirm the diagnosis. The knee was most frequently involved, and most of the lesions were in an ipsilateral extremity. All of the patients received surgical management with curettage or resection. The overall median follow-up was 194 months (interquartile range, 41–336 months). Five of 7 patients had local recurrence (71%), but considering the number of surgically treated lesions, the risk of local recurrence was 33% (5 local recurrences among 15 treated lesions). No lung metastases occurred. Multicentric giant cell tumor of bone tends to exhibit the same aggressive clinical behavior as solitary giant cell tumor of bone. Patients should be monitored for the occurrence of other lesions, especially in the ipsilateral extremity. [
Orthopedics
. 2023;46(6):e376–e380.]
Montherlant lecteur de Montesquieu
Authors: Duroisin Pierre
Published: May 2023

Montesquieu fait partie de ces classiques qu’Henry de Montherlant (1895-1972) a cités tout au long de sa vie et dont il a volontiers nourri son œuvre. Avec les hauts et les bas qu’on lui verra pour d’autres (anciens, modernes ou contemporains) que l’auteur des Lettres persanes,mais sans jamais l’oublier tout à fait. Montesquieu est même de ceux qu’il relit avec une attention particulière au début des années soixante quand il compose sa Guerre civile (1964).
«Punique égyptien… punique en général… punique grec…»: la percezione della cultura fenicia e punica nella Sardegna del xix secolo attraverso le lettere di Léon Gouin
Authors: Mezzolani Andreose Antonella
Published: May 2023

La personnalité de Léon Gouin, ingénieur des mines qui a longtemps vécu en Sardaigne, est bien connue par les spécialistes des antiquités de l’île. Sa raccolta che può dirsi «un museo», selon la définition du chanoine Spano, doyen de l’archéologie sarde, a apporté une contribution très importante au Musée Archéologique National de Cagliari, grâce au matériel allant de la période nuragique à l’époque romaine impériale. Une attention particulière à l’architecture des tombes et aux objets puniques est visible dans les lettres envoyées par l’ingénieur au père Delattre et conservées près de la Casa Generalizia dei Padri Bianchi de Rome : ces documents de correspondance nous permettent de réfléchir sur la perception de la culture punique en Sardaigne après la moitié du xixe siècle par les amateurs d’archéologie, ainsi que sur la pratique fructueuse de l’échange d’informations savantes avec les érudits les plus reconnus.
De l’époque coloniale aux indépendances : que faire de la Carthage punique ?
Authors: Alexandropoulos Jacques
Published: May 2023

Positive ou plus souvent négative et orientaliste, l’image de la Carthage punique prend place dans la culture coloniale pour souligner une limite identitaire, ou aider à la réflexion sur l’empire. C’est en utilisant ce terrain documentaire et idéologique balisé par la science coloniale que l’historien al-Mîlî, lié aux Oulémas de Ben Badis, décrit en 1927 une Carthage proche par ses origines orientales de « la personnalité algérienne », et contribuant largement au développement civilisationnel des Berbères qui font la « nation algérienne ». L’affirmation du FLN amènera une vision plus radicale où Carthage rejoint le camp des impérialistes.
Carthage sur grand écran (1910-2006) : la cité punique au goût des autres
Authors: Bernard Gwladys
Published: May 2023

Si les Phéniciens sont quasiment absents des écrans de cinéma et de télévision, les Carthaginoises et les Carthaginois ont fait leur apparition dès les débuts du cinéma. En 1910, soit douze ans après le premier film d’Antiquité, Didon, la reine de Carthage, surgit sur les écrans italiens, suivie par diverses relectures de Salam(m)bô : l’opéra et la littérature du xixe siècle, sources d’inspiration essentielle du cinéma européen naissant, fournissent au 7e art les premières images et archétypes concernant Carthage, partenaire passionnelle de Rome. Le cinéma italien construit progressivement un mythe cinématographique de l’étrange et terrifiante Carthage, utile pour fasciner et édifier le spectateur européen en le convaincant de la supériorité nécessaire de la cité romaine et de la justification du destin tragique de la cité punique. Le contexte évolue progressivement après la Seconde Guerre mondiale, avec la multiplication des films américains et anglais mettant en scène la figure renouvelée d’Hannibal, et le développement d’un intérêt progressif pour la représentation des Puniques à l’écran, dans un contexte artistique et technique qui évolue jusqu’au « Nouveau Péplum » du xxie siècle.
Applications of AI in Computer-Aided Drug Discovery
Authors: Kohli Reet Kaur , Santoshi Seneha , Yadav Sunishtha S. , Chauhan Vandana
Published: May 2023

Drug discovery is the process in which healthcare is approached through identification of potential new therapeutic agents. CADD provides solutions at every stage of drug discovery including the leading challenges of cost and time. CADD has provided an effective solution to this challenge. AI has enabled multiple aspects of drug discovery, including the analysis of high content screening data and the design and synthesis of new molecules. The use of transparent methodologies like AI is crucial, particularly in drug repositioning/repurposing in rare diseases. An abundant variety of methods, in particular the concepts of deep learning, have been used for protein modelling and ligand-based drug discovery along with artificial neural networks for QSAR modelling. Structure-based ligand identification via AI modelling is also explored. AI presents the scientific community and the biopharma industry and its established processes for discovering and developing new medicines with new challenges.
Lung Cancer Detection Using Deep Learning Techniques
Authors: Sangwan Manya , Gambhir Sapna , Gupta Sumita
Published: May 2023

Early detection that can be done to detect lung cancer is through radiological examination. Chest X-Ray or chest radiography is one of the tools that can be used to analyze lung diseases including pneumonia, bronchitis, and lung cancer. The image from the radiography will show the shape of the lungs difference between normal and abnormal lungs. In abnormal lungs, it will show nodules in the lungs on the results radiography image, but on the other hand, in normal lungs, it does not show nodules in the lungs on the radiographic image. This study to detect lung cancer using radiographic images using deep learning techniques. Therefore, by carrying out early revealing of lung cancer, it is hoped that this scheme will provide suitable action and directions for lung cancer patients and decrease lung cancer transience.
Promoting Policy Perspectives on Self-Directed Learning as a Transformative Strategy for Higher Education
Authors: Seherrie Aloysius Claudian
Published: May 2023

Self-directed learning is an autonomous skill where individuals take responsibility, with or without the help of others, of their learning. The purpose of this chapter is to explore how self-directed learning (SDL) as a transformative strategy in higher education institutions (HEIs) can be promoted. The transformative self-directed learning theory (TSDLT) proposes policy strategies to promote self-directed learning as a transformative strategy for higher education. Policy strategies should be provided to reconstruct their facilitator and guidance abilities through empowerment. Policy stipulations in the Education White Paper 3 were analysed by means of thematic analysis. This chapter provides Freire's critical pedagogy and Kolb's active experiential learning to put forward suggestions to promote SDL as a transformative strategy in South Africa's HEIs. Findings revealed that students can be enhanced in self-directed learning skills, independent learning, and responsibility awareness for their own learning. It is recommended that strategies should be implemented to build confidence.
Postgraduate Student Experiences of Using YouTube as a Research Tool for Learning
Authors: Sokhulu Lerato Hlengiwe
Published: May 2023

YouTube has been a useful educational software tool for teaching and learning. However, there is a need to investigate YouTube as a tool for research at postgraduate level. Through a qualitative case study, five master's students' experiences of YouTube as a research tool for learning are explored. Data were generated using reflective journals and semi-structured interviews. Framed by the Unified Theory of Acceptance and Use of Technology (UTAUT), thematic analysis was used to analyze the data. The findings revealed that students used YouTube to follow step-by-step instructions about research-related processes and to learn how to navigate other digital technologies. Others viewed YouTube as a social platform that was unhelpful and time-consuming. The study recommends that students reflect on their personal learning identities in order to evaluate the usefulness of YouTube in their postgraduate studies.
LMS Course Design for Adult Learning
Authors: Wang Viktor , Torrisi-Steele Geraldine
Published: May 2023

Nearly all educational institutions use learning management systems (LMS). Post-pandemic figures suggest that the uptake of LMS is about 98%. This means that most educators, especially those in post-schooling education, will use, and be responsible for designing, an online course site. While there is a tendency to use course sites as a repository and convenient communication medium, there is an unmet need to design these sites in a way that facilitates learning. As online teaching and learning become more prolific, especially in higher education and adult learning contexts, it is increasingly necessary to design course sites that facilitate learning as opposed to course sites that are just repositories. Just like the approaches that a teacher uses in classroom teaching, the teacher's underpinning philosophy will impact the way they will design their course sites on an LMS or website. Despite technology and online being present for over two decades, course design and teaching in the online environment remains trapped in traditional behaviorist and content-driven approaches.
Learning in Organizations
Authors: Wang Viktor , Torrisi-Steele Geraldine
Published: May 2023

Against the backdrop of emerging technologies, organizations are, now more than ever before, needing to develop agile and innovative mindsets within organizations. To achieve agility and innovation, the humans in the organizations—employees and leaders—must have the capabilities to be self-directed, and they must be driven to identify meaningful problems in the organization and engage in collaborative problem-solving to address the problems. Developing these capabilities rests mostly on the organizational environment as created by the leadership and with the opportunities presented through human resource development. The authors maintain it is useful to anchor in andragogy leadership approaches alongside opportunities for organizational learning but to not discount the value of pedagogy when used appropriately.
Contextual Influences on Leader Development Among Natural Scientists in Uganda
Authors: Lukwago Julius , Martins Ana , Tefera Orthodox
Published: May 2023

The study's aim is to ascertain the role of contextual influences on leader development among natural scientists in Uganda differ from those of non-scientist leaders in the Ugandan context. The study design, methodology, and approach include a retrospective mixed-methods multi-case comparative case study to examine the leader development lifespan experiences of technical expert scientists holding leadership positions in organizations of different sectors. Purposive sampling was used to select senior expert natural scientists providing sustainability leadership at healthcare organizations, at the Uganda Ministry of Agriculture, Animal Industry, and Fisheries and affiliate agencies. Non-scientist leaders from Uganda Revenue Authority were included as a comparator group. Findings reveal that scientists experience normative behaviors right from their undergraduate levels only focused on technical skills being devoid of soft skills. Research limitations and implications direct to the need for developing leaders through coaching and mentoring, as well as leadership succession planning.
Andragogical Leadership and Technology in the Future of Adult Education
Authors: Zhang Yuan , Taylor Jonathan E.
Published: May 2023

The purpose of this chapter is to foster a deeper understanding of andragogy, explore the features of andragogical leadership and investigate the impact of technology in supporting adult learning. With an interest in investing and carving out new territory in andragogy, the authors discuss andragogical leadership and technology in promoting collaborative learning in adults. In this chapter, they revisit andragogy from a different angle: andragogy's relation with leadership. With the teaching practice drawn from the integration of technology into adult English as a second or foreign language (ESL/EFL) online learning, they investigate the role of andragogical leadership in constructing the community of inquiry.
Leading Through Digital Andragogy
Authors: Ellington Linda Marie
Published: May 2023

The tsunami of technological change in higher education is causing disruption throughout academia and is exerting influence on leading in formal education. In much the same way that industries experienced disruption from the digital revolution, andragogy is on the verge of what could be called a learning-tech culture revolution. This chapter focuses on two critical aspects that present potential impact in education, the leader, and the adult learner. The purpose of this literature review is to identify challenges leaders face in the digital landscape and strategies relevant to innovative techniques for digital adult learners.
Navigating Uncertainty and the Unknown
Authors: Green Wendy M. , Hansman Catherine A. , Lalwani Anil
Published: May 2023

Within the global community, the only constant is change. In Spring 2020, as COVID-19 became a global pandemic, countries closed their borders and closed schools, businesses, and governments. Universities that already had significant online presences and available courses/programs could be reassured that at least some of their programming would continue with minimal interruption. Effective university leaders were able to identify paths forward for their institutions that encompassed their education and were much more able to support faculty, staff, and students with the abrupt change. The authors look at professors as learning leaders, the leadership in higher education institutions, as well as leadership in the private sector. They examine how andragogical leadership can be utilized to shift current educational practices and consider how we might shape learning environments in order to foster more robust learning environments. But essentially, they explain how education leaders develop and organize institutional learning as technology continues to play an essential role.
Addressing Violence in the U.S. Public School System
Authors: Sartin S. Renee
Published: May 2023

This chapter will discuss specific mass school shootings that occurred in areas throughout the United States, beginning with the Columbine School shooting in 1999. This chapter is designed to give the reader a closer look into the devastation these families experienced. Although the surviving children and their families continue to live through the horror of their child being killed in the manner in which they were, the media is forced to move on to another city, or another state to cover another school shooting. We now have a nation with an “increasingly growing number” of traumatized families.
Who Is Supposed to Teach Us About This?
Authors: Simmons Jonathan
Published: May 2023

The central aim of teacher education is to prepare pre-service teachers for the classroom. This includes a variety of courses and experiences supporting their developing understanding of learning theory and pedagogy. However, too often, teacher education does not fully prepare future teachers for the complex conversations that they must navigate in their classrooms. This is particularly true where topics such as school violence, grief and loss are concerned. But these difficult conversations are part of the reality of teaching. As of 2023 only five states have not had a death caused by a school shooting. Further it is estimated that 7 out of 10 teachers currently have a student processing grief in their classroom. Pre-service teachers need guidance and training to navigate these conversations. This chapter offers a series of principles that guide teacher educators to consider how to address school violence, loss, and grief in teacher education.
An Umbrella Review of the Literature on Blockchain and Distributed Ledger Technology and Their Roles in Future Banking
Authors: Ankita  , Trivedi Sonal
Published: May 2023

Blockchain technology is gaining popularity in the financial sector and specifically in banking. Its implementation will result into increased transparency and reduced cost. Distributed ledger technology (DLT) is primarily a payment system that is well adopted by the financial sector and will have significant impact on future of banking. The purpose of the study is to identify whether this novel technology is good enough to replace and compete with the traditional financial system. The current study followed the umbrella review limiting the studies based on blockchain, DLT, and banking from 2015 until today published in Scopus-indexed journals. The study concludes that there is evidence of adoption of blockchain technology in banking sectors around the globe, but there is still need to explore the application of blockchain in banking, and there is a need to overcome the challenges faced in implementation of blockchain in the banking sector.
Sustainable Approaches of Blockchain Tech, Artificial Intelligence, and Climate Finance in the 4&5IR
Authors: Bhattacharjee Amitab , Bansal Vikram
Published: May 2023

Save the green and live in the green should be the mottos of the modern high-tech world. Industry 4.0 introduces the most advanced automated technologies, but many of them cause high CO2 emissions around the globe that need strong compelling force because any catastrophic changes in the climate causes dreadful vandalization in the economy and society. This chapter discusses the climate-friendly economic and low-emission technological developments in the 4IR and 5IR by using the practical-sense mechanism. Reading this chapter will therefore increase the knowledge of blockchain technology (BT), artificial intelligence (AI), and climate finance in the low carbon economic sustainability. Furthermore, the proposed green development themes (i.e., hybrid green city and industrial layout, hybrid low emission agriculture farm) affirms the sustainable low carbon economic developments in the forthcoming Industry 5.0. Finally, the strategic recommendations will assist in developing the low carbon economy with the perfection of BT, AI, and global climate finance in the world.
Cryptocurrency Adoption Behaviour of Millennial Investors in India
Authors: Sharma Renuka , Mehta Kiran , Rana Ritik
Published: May 2023

Young investors, fuelled by the hype and ads, are rushing to cryptocurrency exchanges with the hopes of generating rapid riches, and investors of the millennial generation especially believe cryptocurrency can make them billionaires. Crypto Research and Intelligence Business found that over 15 million Indians had accepted cryptocurrencies and invested close to $10 billion in crypto assets. Because of the ongoing changes over the last few years, changing from paper to virtual currency, a new type of currency, namely cryptocurrency, has emerged. Shorter transaction times and lower transfer fees are two of the advantages that cryptocurrencies offer to their potential users. The concept of cryptocurrency is underpinned by decentralised technology, which has captivated the interest of a variety of stakeholders. This research examines millennial cryptocurrency adoption behaviour in India.
Blockchain Technology Use to Streamline Climate Investment
Authors: Sugathan Surabhi
Published: May 2023

The main objective of this chapter is to contour the climate investing by implementing blockchain technology, which will lead to transparency within the network. Climate investing aids the companies that are involved in reducing carbon emissions, subsidising the usage of fossil fuels and manufacturing alternate options. This investment will be directly propositional to the “green revolution,” which the Indian government is making efforts towards. Blockchain technology will help towards this investment by creating a transparent and secured network that is impossible to hack. The database management will be designed using the latest programming techniques, which may also include artificial intelligence. Climate finance includes the financial resources which has been used to support the sustainability and climate change.
Cryptocurrency Adoption
Authors: Singh Kochar Sahibpreet
Published: May 2023

This chapter examines how familiarity influences the adoption and how education may increase cryptocurrency users. This project will use a systematic approach highlighting the growth of acceptance of cryptocurrency from 2017 to 2023 using a mixed methods approach since there has been little research on how individuals have embraced and accepted cryptocurrencies. Due to a lack of study, this study examines cryptocurrency adoption, its drivers, and its hazards. This study's outcomes will be a form of Literature Review for future research, increase knowledge of cryptocurrency acceptance, and help in cryptocurrency adoption.
Trending Technologies in the Cryptocurrency Market
Authors: Taherdoost Hamed
Published: May 2023

Cryptocurrencies that are virtual and dematerialized are online and entirely digital currencies. Cryptocurrency has been the subject of many studies from different aspects; however, it is still a new area of investment for businesses as there are positive trends in the crypto space. Trending technologies, on the other hand, are making significant changes in all industries, and the cryptocurrency market is no exception. The employment of trending technologies can facilitate the crypto market with pattern recognition and secure transactions. This chapter aims to analyze the application of trending technologies in the crypto market and the benefits they can add to traders and brokers.
Identification of a novel splice site mutation in the DNAAF4 gene of a Chinese patient with primary ciliary dyskinesia
Authors: Xu Yang , Wang Jing , Liu Ji-Hai , Gao Qing-Qiang , Wang Bing , Xu Zhi-Peng
Published: May 2023

Primary ciliary dyskinesia (PCD) is a rare hereditary orphan condition that results in variable phenotypes, including infertility. About 50 gene variants are reported in the scientific literature to cause PCD, and among them, dynein axonemal assembly factor 4 (DNAAF4) has been recently reported. DNAAF4 has been implicated in the preassembly of a multiunit dynein protein essential for the normal function of locomotory cilia as well as flagella. In the current study, a single patient belonging to a Chinese family was recruited, having been diagnosed with PCD and asthenoteratozoospermia. The affected individual was a 32-year-old male from a nonconsanguineous family. He also had abnormal spine structure and spinal cord bends at angles diagnosed with scoliosis. Medical reports, laboratory results, and imaging data were investigated. Whole-exome sequencing, Sanger sequencing, immunofluorescence analysis, hematoxylin-eosin staining, and in silico functional analysis, including protein modeling and docking studies, were used. The results identified DNAAF4 disease-related variants and confirmed their pathogenicity. Genetic analysis through whole-exome sequencing identified two pathogenic biallelic variants in the affected individual. The identified variants were a hemizygous splice site c.784-1G>A and heterozygous 20.1 Kb deletion at the DNAAF4 locus, resulting in a truncated and functionless DNAAF4 protein. Immunofluorescence analysis indicated that the inner dynein arm was not present in the sperm flagellum, and sperm morphological analysis revealed small sperm with twisted and curved flagella or lacking flagella. The current study found novel biallelic variants causing PCD and asthenoteratozoospermia, extending the range of DNAAF4 pathogenic variants in PCD and associated with the etiology of asthenoteratozoospermia. These findings will improve our understanding of the etiology of PCD.
Predictive factors for efficacy of testosterone replacement therapy for late-onset hypogonadism in Japanese men: a preliminary report
Authors: Kondoh Nobuyuki , Kaizuka Yohei , Nagasawa Seiji , Togo Yoshikazu , Yamamoto Shingo
Published: May 2023

Although testosterone replacement therapy (TRT) is the first-choice method used worldwide for late-onset hypogonadism (LOH), clinical benefits are not seen in all cases. This study was conducted to determine the predictors of TRT efficacy for LOH. Fifty-six patients who visited our Men’s Health Clinic (Kawanishi City Medical Center, Kawanishi and Hyogo Medical University, Nishinomiya, Hyogo, Japan) between November 2003 and June 2021 with data available before and after TRT were enrolled. They were divided into responders (Group 1; n = 45, accounting for 80.4%) and nonresponders (Group 2; n = 11, accounting for 19.6%) based on the clinical response to TRT, including patient satisfaction. Factors noted before TRT included age, body mass index, aging males’ symptoms score, sexual health inventory for men, luteinizing hormone, follicular-stimulating hormone, testosterone, free testosterone, prolactin (PRL), estradiol (E2), and testosterone/estradiol (T/E2) ratio in serum. For statistical analysis, a multivariable logistic regression model was used. Univariate analysis revealed PRL (odds ratio [OR]: 0.9624; 95% confidence interval [CI]: 0.9316–0.9943, P < 0.05), E2 (OR: 0.8692; 95% CI: 0.7745–0.9754, P < 0.05), and T/E2 ratio (OR: 1.1312; 95% CI: 1.0106–1.2661, P < 0.05) to be predictive factors. Multivariate analyses showed that T/E2 ratio was an independent predictive factor (OR: 1.1593; 95% CI: 1.0438–1.2875, P < 0.01). The present results suggest that a low value for T/E2 ratio may predict a reduced response to TRT. The T/E2 ratio threshold to predict nonresponders based on receiver-operating characteristics (ROC) curve analysis was shown to be 17.3. Although additional studies with larger number of patients are necessary, we propose the determination of serum E2 level and testosterone level prior to performing TRT.
Effect of transcranial direct current stimulation on puzzle-solving ability in stroke patients with cognitive dysfunction
Authors: Kumar Sanjiv , Sumant Saniya
Published: May 2023

PURPOSE:

Stroke lies among the most disabling diseases and is world-wide a leading cause of death. Most of the stroke patients experience cognitive deficits associated with executive dysfunction (decision making, problem solving, working memory, and cognitive flexibility). Executive dysfunction in stroke makes the patients vulnerable to depression, anxiety as their daily activities like personal, social, cultural and occupational are severely affected. Thus, the dependency increases and their quality of life decreases. Problem solving is one such important executive function required in day-to-day life. Puzzle solving reflects onto ones problem-solving ability that requires understanding, conceptual knowledge recruitment, novel and insightful thinking, and processing a solution. The purpose of this study was to determine if noninvasive brain stimulation has any effect on puzzle-solving ability of stroke patients and to assess their performance on the same.

METHOD:

A 3-week interventional study on 11 stroke participants was done. The samples were assessed at baseline for cognitive impairment using Montreal Cognitive Assessment Scale. Participants with scores <26 were given a 30-piece Jigsaw Puzzle to solve and Wisconsin Card Sorting Test (WCST) was done, both at baseline and after 3 weeks.

RESULTS:

This study confirmed that there was improvement in the performance of solving the Jigsaw Puzzle after application of transcranial direct current stimulation (TDCS) (P = 0.005), but the scores on WCST showed no significant reliable change (P = 0.192).

CONCLUSION:

This study concluded that TDCS is effective in improving puzzle-solving ability in stroke patients.
Older Age in Subarachnoid Neurocysticercosis Reflects a Long Prepatent Period
Authors: Nateros Fernando , Saenz Edith , Saavedra Herbert , Gonzales Isidro , Pretell E. Javier , Perez Erika , Castillo Yesenia , Bustos Javier A. , Garcia Hector H. , _ _
Published: May 2023

Patients with subarachnoid neurocysticercosis (NCC) are usually older than those with parenchymal disease. Whether this difference reflects a prolonged presymptomatic period or a delay in diagnosis is not clear. From 408 eligible patients, we retrospectively compared the age at symptom onset in 140 patients diagnosed with parenchymal (pure viable or pure calcified) and subarachnoid NCC who had a confirmatory image available not more than 2 years after the beginning of symptoms. Patients with mixed (parenchymal and subarachnoid) NCC or those with parenchymal cysts at different stages (viable and/or degenerating and/or calcified) were not included. After controlling by sex and residence in rural endemic regions, the mean age at symptom onset in patients with subarachnoid disease was 13.69 years older than those with viable parenchymal disease. A long incubation period is a major contributing factor to older age at presentation in subarachnoid NCC, independent of delayed diagnosis or access to care.
Why Did Black Soldiers Historically Have More Pneumonia Than White Soldiers in the U.S. Army?
Authors: Shanks G. Dennis
Published: May 2023

Black U.S. Army soldiers had four times as much bacterial pneumonia as White U.S. Army soldiers during both the U.S. Civil War and World War I (WWI). Pneumonia case fatality rates were a third greater in Black soldiers during the U.S. Civil War, but were the same between the racial groups by WWI. During WWII, the use of antibiotics decreased bacterial pneumonia mortality rates 100-fold and apparently erased racial differences. Similar differences in bacterial pneumonia rates by racial group were observed in African colonial soldiers of the French and British Armies during WWI. Pneumonia rates in Indian, Filipino, and Puerto Rican soldiers suggested that genetic polymorphisms were not a decisive factor determining Black pneumonia mortality. Postmeasles pneumonias did not suggest an immune deficit in Black soldiers. Geographic focus of pneumonia in Black soldiers from the southern U.S. states and other tropical regions raises the possibility that increased bacterial pneumonia rates were related indirectly to malaria infections. Malaria remains a difficult-to-measure but potentially important mortality risk factor in pneumonia.
Salud mental y rendimiento académico en estudiantes de educación media superior en un entorno pospandémico.
Authors: Gómez Delgado Guillermo , Ramírez Mireles Jaime Eduardo
Published: May 2023

La educación con nula o presencialidad limitada se extendió a dos años, por lo que resultó preponderante evaluar los indicadores de la salud mental y su correlación al rendimiento académico en estudiantes adscritos al Sistema de Educación Media Superior. Con un diseño de investigación descriptivo, transversal y de alcance correlacional, se aplicaron las psicometrías (ISO-30, KIDSCREEN-52, APGAR familiar, Escala de Impulsividad y Gaudibilidad) a través de un muestreo no probabilístico. A retorno a las aulas, se identificó una prevalencia de problemáticas relacionadas con la salud mental, como conductas de riesgo a suicidio (24.4%), impulsivas (43.6%), disfunción familiar (29.5%), baja calidad de vida relacionada con la salud y disfrute de las actividades que realizan en entorno pospandémico.
Estrategias Socioemocionales para el desarrollo de la Autoestima en niños de 4 a 5 años.
Authors: Lluglla Minta Erika Jazmin , Toapanta Quinatoa Tania Maribel , Bravo Zambonino José María
Published: May 2023

Este artículo aborda la autoestima como un elemento fundamental en la formación de la personalidad de los niños, puesto que favorece el desarrollo del aprendizaje, la construcción de buenas relaciones y el control de sus emociones. Para realizar lo anterior, se desarrolló una guía didáctica de estrategias lúdicas, en niños de 4 a 5 años, utilizando un enfoque cualitativo, descriptivo y de campo, utilizando los métodos inductivo, deductivo, bibliográfico, así como los instrumentos de recolección de la información como la observación con su instrumento la lista de cotejo, mismos que permitieron el establecimiento de la discusión y concluir que se deben aplicar estas estrategias para que los niños socialicen y pongan en práctica sus habilidades emocionales y sociales.
Importancia de la Escuela Nueva en el desarrollo socioemocional.
Authors: Atiaja Acosta Gabriela Mishell , Reasco Boya María José , Bravo Zambonino José María
Published: May 2023

El presente artículo revela la importancia de la Escuela Nueva en el desarrollo socioemocional de los infantes. Se tomó como punto de partida el problema: los docentes desconocen el referido modelo pedagógico y la institución educativa sigue aplicando el modelo tradicional, lo que ha conllevado a la disminución de relaciones socioemocionales en los infantes. Para su solución, se diseñó, validó y aplicó una guía de estrategias lúdicas basado en el modelo de la Escuela Nueva, proceso que asumió el enfoque cualitativo y la investigación descriptiva, se aplicaron los métodos inductivo y deductivo, y la técnica de la observación con su instrumento lista de cotejo, que permitió valorar el desarrollo socioemocional, demostrar los resultados obtenidos y arribar a conclusiones.
Juegos didácticos para el desarrollo de la autonomía en el proceso de enseñanza- aprendizaje en los niños de preparatoria.
Authors: Albán Quispe María Fernanda , Perdomo Chiquito Blanca Isabel , Borja Padilla Tania Margarita
Published: May 2023

El presente estudio tiene como propósito determinar la efectividad que tiene los juegos didácticos en el proceso de enseñanza- aprendizaje en los niños de nivel de preparatoria y la aplicación del juego-trabajo como estrategia didáctica para lograr desarrollar la autonomía. La investigación del año 2021-2022 con la metodología cualitativa, utilizando instrumentos como la encuesta y la entrevista permitió conocer el déficit de la autonomía; por tal motivo, se elaboró una guía de estrategias y actividades lúdicas, que promuevan el desarrollo emocional del infante en su entorno familiar y educativo. Se concluye que las actividades lúdicas propiciaron el fortalecimiento de la autonomía e independencia de los niños.