bluuebunny/crossref_metadata_2025 huggingface dataset:
Portfolio Risk Assessment under Dynamic (Equi)Correlation and Semi-Nonparametric Estimation: An Application to Cryptocurrencies
Authors: Jiménez Inés , Mora-Valencia Andrés , Ñíguez Trino-Manuel , Perote Javier
Published: November 2020

The semi-nonparametric (SNP) modeling of the return distribution has been proved to be a flexible and accurate methodology for portfolio risk management that allows two-step estimation of the dynamic conditional correlation (DCC) matrix. For this SNP-DCC model, we propose a stepwise procedure to compute pairwise conditional correlations under bivariate marginal SNP distributions, overcoming the curse of dimensionality. The procedure is compared to the assumption of dynamic equicorrelation (DECO), which is a parsimonious model when correlations among the assets are not significantly different but requires joint estimation of the multivariate SNP model. The risk assessment of both methodologies is tested for a portfolio of cryptocurrencies by implementing backtesting techniques and for different risk measures: value-at-risk, expected shortfall and median shortfall. The results support our proposal showing that the SNP-DCC model has better performance for lower confidence levels than the SNP-DECO model and is more appropriate for portfolio diversification purposes.
The General Fractional Derivative and Related Fractional Differential Equations
Authors: Luchko Yuri , Yamamoto Masahiro
Published: November 2020

In this survey paper, we start with a discussion of the general fractional derivative (GFD) introduced by A. Kochubei in his recent publications. In particular, a connection of this derivative to the corresponding fractional integral and the Sonine relation for their kernels are presented. Then we consider some fractional ordinary differential equations (ODEs) with the GFD including the relaxation equation and the growth equation. The main part of the paper is devoted to the fractional partial differential equations (PDEs) with the GFD. We discuss both the Cauchy problems and the initial-boundary-value problems for the time-fractional diffusion equations with the GFD. In the final part of the paper, some results regarding the inverse problems for the differential equations with the GFD are presented.
A Sulfated Polysaccharide from Saccharina japonica Suppresses LPS-Induced Inflammation Both in a Macrophage Cell Model via Blocking MAPK/NF-κB Signal Pathways In Vitro and a Zebrafish Model of Embryos and Larvae In Vivo
Authors: Wang Shengnan , Ni Liying , Fu Xiaoting , Duan Delin , Xu Jiachao , Gao Xin
Published: November 2020

Inflammation is a complicated host-protective response to stimuli and toxic conditions, and is considered as a double-edged sword. A sulfated Saccharinajaponica polysaccharide (LJPS) with a sulfate content of 9.07% showed significant inhibitory effects against lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 macrophage cells and zebrafish. Its chemical and structural properties were investigated via HPLC, GC, FTIR, and NMR spectroscopy. In vitro experiments demonstrated that LJPS significantly inhibited the generation of nitric oxide (NO) and prostaglandin E2 (PGE2) via the downregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression and suppressed pro-inflammatory cytokines tumor necrosis factor (TNF)-α and interleukin (IL)-1β production via the nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signal pathways in LPS-induced RAW 264.7 cells. Moreover, LJPS showed strong protective effects against LPS-induced inflammatory responses in zebrafish, increasing the survival rate, reducing the heart rate and yolk sac edema size, and inhibiting cell death and the production of intracellular reactive oxygen species (ROS) and NO. Its convenience for large-scale production and significant anti-inflammatory activity indicated the potential application of LJPS in functional foods, cosmetics, and pharmaceutical industries.
Evaluating Retinal and Choroidal Perfusion Changes After Ocular Massage of Healthy Eyes Using Optical Coherence Tomography Angiography
Authors: Rommel Felix , Lüken Sabine , Prasuhn Michelle , Kurz Maximilian , Kakkassery Vinodh , Grisanti Salvatore , Ranjbar Mahdy
Published: November 2020

Background and objectives: Ocular massage (OM) is used as a treatment option for acute retinal artery occlusion, under the assumption that it induces vessel dilatation and enhances perfusion. Since evidence of ocular perfusion alteration due to OM is lacking, we investigate the impact of OM on the hemodynamics of the posterior pole in healthy eyes in a noninvasive fashion by using optical coherence tomography angiography (OCTA). Materials and Methods: A prospective study was conducted on healthy volunteers, each of whom underwent measurements of intraocular pressure (IOP), central macular thickness (CMT), subfoveal choroidal thickness (SFCT), radial peripapillary capillary perfusion (RPCP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattler’s layer perfusion (SLP) and Haller’s layer perfusion (HLP) before and after OM. OM was performed for 2 min, consisting of 10-s turns of compression and decompression of the globe. Results: A total of 21 eyes from 21 participants (median age 29) were included. After OM, IOP significantly declined (p < 0.001), while SFCT (p < 0.005), SCPP (p < 0.001), DCPP (p = 0.004) and CCP (p = 0.008) significantly increased. CMT, RPCP, SLP and HLP did not show any significant alteration due to OM. Changes in SCPP correlated positively with changes in CCP and vice versa. Conclusions: OCTA-based analysis in healthy adults following OM demonstrated a significant increase of retinal perfusion values, assumed to be due to failure of autoregulatory mechanisms. These findings may indicate a positive effect of OM as a treatment option for patients with acute retinal artery occlusion.
Nurses Training and Capacitation for Palliative Care in Emergency Units: A Systematic Review
Authors: Ortega Romero Sonia , Velando-Soriano Almudena , Romero-Bejar José Luis , Vargas-Román Keyla , Albendín-García Luis , Suleiman-Martos Nora , Cañadas-De la Fuente Guillermo Arturo
Published: November 2020

Background and objectives: Palliative care (PC) prevents and alleviates patients´ suffering to improve their quality of life in their last days. In recent years, there has been an increase in visits to the emergency services (ES) by patients who may need this type of care. The aims were to describe the training and capacitation of nurses from ES in PC. Accordingly, a systematic review was performed. Materials and Methods: Medline, Scopus, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used. The search equation was “Palliative care and nursing care and emergency room”. A total of 12 studies were selected. Results: The studies agree on the need for training professionals in PC to provide a higher quality care, better identification of patient needs and to avoid unnecessary invasive processes. Similarly, the implementation of a collaborative model between ES and PC, the existence of a PC specialized team in the ES or proper palliative care at home correspond to a decrease in emergency visits, a lower number of hospitalizations or days admitted, and a decrease in hospital deaths. Conclusions: The development of PC in the different areas of patient care is necessary. Better palliative care leads to a lower frequency of ES by terminal patients, which has a positive impact on their quality of life. Access to PC from the emergency unit should be one of the priority health objectives due to increment in the aged population susceptible to this type of care.
Chronic Kidney Disease, Gut Dysbiosis, and Constipation: A Burdensome Triplet
Authors: Ikee Ryota , Sasaki Naomi , Yasuda Takuji , Fukazawa Sawako
Published: November 2020

Gut dysbiosis has been implicated in the progression of chronic kidney disease (CKD). Alterations in the gut environment induced by uremic toxins, the dietary restriction of fiber-rich foods, and multiple drugs may be involved in CKD-related gut dysbiosis. CKD-related gut dysbiosis is considered to be characterized by the expansion of bacterial species producing precursors of harmful uremic toxins, such as indoxyl sulfate and p-cresyl sulfate, and the contraction of species generating beneficial short-chain fatty acids, such as butyrate. Gut-derived uremic toxins cause oxidative stress and pro-inflammatory responses, whereas butyrate exerts anti-inflammatory effects and contributes to gut epithelial integrity. Gut dysbiosis is associated with the disruption of the gut epithelial barrier, which leads to the translocation of endotoxins. Research on CKD-related gut dysbiosis has mainly focused on chronic inflammation and consequent cardiovascular and renal damage. The pathogenic relationship between CKD-related gut dysbiosis and constipation has not yet been investigated in detail. Constipation is highly prevalent in CKD and affects the quality of life of these patients. Under the pathophysiological state of gut dysbiosis, altered bacterial fermentation products may play a prominent role in intestinal dysmotility. In this review, we outline the factors contributing to constipation, such as the gut microbiota and bacterial fermentation; introduce recent findings on the pathogenic link between CKD-related gut dysbiosis and constipation; and discuss potential interventions. This pathogenic link needs to be elucidated in more detail and may contribute to the development of novel treatment options not only for constipation, but also cardiovascular disease in CKD.
Correlation between Human Papillomavirus Codetection Profiles and Cervical Intraepithelial Neoplasia in Japanese Women
Authors: Okayama Kaori , Kimura Hirokazu , Teruya Koji , Ishii Yasuyoshi , Fujita Kiyotaka , Fujii Masahiko , Oda Mizue , Sasagawa Toshiyuki , Okodo Mitsuaki
Published: November 2020

Human papillomavirus (HPV) infection is thought to be strongly associated with the precarcinomatous state cervical intraepithelial neoplasia (CIN) and cervical carcinoma. To accurately assess the correlation between HPV detection profiles and CIN, the uniplex E6/E7 polymerase chain reaction (PCR) method was used. We detected HPV (37 genotypes) in 267 CIN cases. The detection of a single high-risk HPV genotype occurred in 69.7% of CIN1 and worse than CIN1 (CIN1+) cases whereas other types were detected in 11.6% of cases. Codetection of high-risk HPV genotypes occurred in 4.9% of CIN1+ cases. The high-risk genotype HPV16 was the most frequently detected genotype in CIN1+ lesions; the genotype HPV34 (not a high-risk type) was detected in some CIN3 cases. Furthermore, HPV codetection may not be associated with CIN grades. These results suggest that various HPV genotypes are associated with CIN across all analyzed cases.
The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
Authors: Chateau Alice , Van der Verren Sander E. , Remaut Han , Fioravanti Antonella
Published: November 2020

Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Because of their easy to access extracellular locations, B. anthracis cell envelope components represent interesting targets for the identification and development of novel therapeutic and vaccine strategies. This review will focus on the novel insights regarding the composition, physiological role, and clinical relevance of B. anthracis cell envelope components.
Comparative Metagenomics of Palearctic and Neotropical Avian Cloacal Viromes Reveal Geographic Bias in Virus Discovery
Authors: Truchado Daniel A. , Llanos-Garrido Alejandro , Oropesa-Olmedo David A. , Cerrada Belén , Cea Pablo , Moens Michaël A. J. , Gomez-Lucia Esperanza , Doménech Ana , Milá Borja , Pérez-Tris Javier , Cadar Daniel , Benítez Laura
Published: November 2020

Our understanding about viruses carried by wild animals is still scarce. The viral diversity of wildlife may be best described with discovery-driven approaches to the study of viral diversity that broaden research efforts towards non-canonical hosts and remote geographic regions. Birds have been key organisms in the transmission of viruses causing important diseases, and wild birds are threatened by viral spillovers associated with human activities. However, our knowledge of the avian virome may be biased towards poultry and highly pathogenic diseases. We describe and compare the fecal virome of two passerine-dominated bird assemblages sampled in a remote Neotropical rainforest in French Guiana (Nouragues Natural Reserve) and a Mediterranean forest in central Spain (La Herrería). We used metagenomic data to quantify the degree of functional and genetic novelty of viruses recovered by examining if the similarity of the contigs we obtained to reference sequences differed between both locations. In general, contigs from Nouragues were significantly less similar to viruses in databases than contigs from La Herrería using Blastn but not for Blastx, suggesting that pristine regions harbor a yet unknown viral diversity with genetically more singular viruses than more studied areas. Additionally, we describe putative novel viruses of the families Picornaviridae, Reoviridae and Hepeviridae. These results highlight the importance of wild animals and remote regions as sources of novel viruses that substantially broaden the current knowledge of the global diversity of viruses.
Effect of AuNPs and AgNPs on the Antioxidant System and Antioxidant Activity of Lavender (Lavandula angustifolia Mill.) from In Vitro Cultures
Authors: Jadczak Paula , Kulpa Danuta , Drozd Radosław , Przewodowski Włodzimierz , Przewodowska Agnieszka
Published: November 2020

The aim of this study was to determine the effect of gold and silver nanoparticles on the activity of antioxidant enzymes (ascorbate peroxidase (APX), superoxide dismutase (SOD), guaiacol peroxidase (POX), and catalase (CAT)), the free radical scavenging capacity, and the total polyphenol capacity of lavender (Lavandula angustifolia Mill.) cultivar “Munstead” propagated in vitro. In the experiment, fragments of lavender plants were cultivated in vitro on medium with the addition of 1, 2, 5, 10, 20, and 50 mg∙dm−3 of AgNPs or AuNPs (particle sizes 24.2 ± 2.4 and 27.5 ± 4.8 nm, respectively). It was found that the nanoparticles increase the activity of the antioxidant enzymes APX and SOD; however, the reaction depends on the NP concentration. The highest APX activity is found in plants propagated on media with 2 and 5 mg∙dm−3 of AgNPs. AuNPs significantly increase the APX activity when added to media with a concentration of 10 mg∙dm−3. The highest SOD activity is recorded at 2 and 5 mg∙dm−3 AgNP and AuNP concentrations. The addition of higher concentrations of nanoparticles to culture media results in a decrease in the APX and SOD activity. The addition of AuNPs to culture media at concentrations from 2 to 50 mg∙dm−3 increases the POX activity in comparison to its activity when AgNPs are added to the culture media. No significant influence of NPs on the increase in CAT activity was demonstrated. AgNPs and AuNPs increased the free radical scavenging capacity (ABTS•+). The addition of NPs at concentrations of 2 and 5 mg∙dm−3 increased the production of polyphenols; however, in lower concentrations it decreased their content in lavender tissues.
Serotypes and Vaccine Coverage of Streptococcus Pneumoniae Colonization in the Nasopharynx of Thai Children in Congested Areas in Chiang Mai
Authors: Wangirapan Anchalee , Ayuthaya Satja Issaranggoon na , Katip Wasan , Kasatpibal Nongyao , Mektrirat Raktham , Anukool Usanee , Oberdorfer Peninnah
Published: November 2020

Streptococcus pneumoniae causes around 10% of all deaths in children younger than five years of age. This study aimed to examine the serogroups/serotypes of S. pneumoniae colonization and vaccine serotype coverage of this organism among Thai children. Nasopharyngeal swabs of children less than or equal to 15 years of age were obtained in congested areas in Chiang Mai from 1 February 2013 to 1 August 2013. The serotyping of S. pneumoniae isolates was performed using the ImmuLex™ kit and the vaccine serotype coverage for this organism was evaluated. A total of 292 children were enrolled. One hundred and thirty children (44.5%) had nasopharyngeal colonization with Streptococcus pneumoniae. Eighty-seven (66.9%) isolates were from children younger than five years of age, seventeen (13.1%) were from children aged 6–10 years, and twenty-six (20%) were from children aged 11–15 years. The five most common serogroups/serotypes isolated were 6 (6A, 6B, 6C) (46.1%), 23 (23F, 23A, 23B) (14.6%), 19 (19F, 19A, 19B, 19C) (8.5%), 15 (15F, 15A, 15B, 15C) (6.9%), and 14 (6.1%). Vaccine serotype coverages in pneumococcal conjugate vaccines (PCV):PCV7, PCV10, and PCV13 were 79.1%, 83.6%, and 85.9%, respectively. There were significant increases in coverage between PCV7 and PCV10 (from 79.1% to 83.6%, p < 0.001), PCV7 and PCV13 (from 79.1% to 85.9%, p < 0.001), and PCV10 and PCV13 (from 83.6% to 85.9%, p < 0.001). The majority of pneumococcal serogroup/serotype colonization in the nasopharynx of Thai children in the studied areas was included in the current licensed pneumococcal conjugated vaccines (PCVs). PCV vaccination should be considered for high-risk children to reduce the incidence of invasive pneumococcal disease among Thai children.
The Key Roles of Interferon Lambda in Human Molecular Defense against Respiratory Viral Infections
Authors: Lozhkov Alexey A. , Klotchenko Sergey A. , Ramsay Edward S. , Moshkoff Herman D. , Moshkoff Dmitry A. , Vasin Andrey V. , Salvato Maria S.
Published: November 2020

Interferons (IFN) are crucial for the innate immune response. Slightly more than two decades ago, a new type of IFN was discovered: the lambda IFN (type III IFN). Like other IFN, the type III IFN display antiviral activity against a wide variety of infections, they induce expression of antiviral, interferon-stimulated genes (MX1, OAS, IFITM1), and they have immuno-modulatory activities that shape adaptive immune responses. Unlike other IFN, the type III IFN signal through distinct receptors is limited to a few cell types, primarily mucosal epithelial cells. As a consequence of their greater and more durable production in nasal and respiratory tissues, they can determine the outcome of respiratory infections. This review is focused on the role of IFN-λ in the pathogenesis of respiratory viral infections, with influenza as a prime example. The influenza virus is a major public health problem, causing up to half a million lethal infections annually. Moreover, the virus has been the cause of four pandemics over the last century. Although IFN-λ are increasingly being tested in antiviral therapy, they can have a negative influence on epithelial tissue recovery and increase the risk of secondary bacterial infections. Therefore, IFN-λ expression deserves increased scrutiny as a key factor in the host immune response to infection.
Efficacy of an Objective Structured Clinical Examination Training Approach for Training Pharmacy Students in Diabetes Mellitus Counseling: A Randomized Controlled Trial
Authors: Farahani Imaneh , Farahani Samieh , Deters Maira A. , Schwender Holger , Laeer Stephanie
Published: November 2020

Pharmacists’ tasks are multifaceted and include, for example, vital counseling and communication skills. Objective Structured Clinical Examinations (OSCEs) could be used to train pharmacy students in these skills. Our study sought to determine the efficacy of our OSCE training approach for training pharmacy students’ counseling and communication skills on diabetes mellitus compared to a control group. This randomized controlled study was conducted with pharmacy students using a pre-post-design. The intervention group completed diabetes OSCE training, while the control group solved diabetes patient cases using subjective, objective, assessment, and plan notes. Before and after the respective training, both groups completed OSCEs evaluating counseling and communication skills. Before each OSCE encounter, the participants completed a self-assessment questionnaire and, upon completion of the seminar, filled out a satisfaction survey. The OSCE-trained group demonstrated a significantly greater increase in counseling and communication skills and self-confidence than the control group. Both groups were generally satisfied with the seminar. These results demonstrate that our OSCE training approach allows for the effective training of pharmacy students’ diabetes counseling and communication skills and suggests the inclusion of such a skill-based approach more widely in pharmacy students’ education.
Analysis of Genetic Diversity and Population Structure of Pigeonpea [Cajanus cajan (L.) Millsp] Accessions Using SSR Markers
Authors: Kimaro Didas , Melis Rob , Sibiya Julia , Shimelis Hussein , Shayanowako Admire
Published: November 2020

Understanding the genetic diversity present amongst crop genotypes is an efficient utilization of germplasm for genetic improvement. The present study was aimed at evaluating genetic diversity and population structure of 48 pigeonpea genotypes from four populations collected from diverse sources. The 48 pigeonpea entries were genotyped using 33 simple sequence repeat (SSR) markers that are polymorphic to assess molecular genetic diversity and genetic relatedness. The informative marker combinations revealed a total of 155 alleles at 33 loci, with an average of 4.78 alleles detected per marker with the mean polymorphic information content (PIC) value of 0.46. Population structure analysis using model based revealed that the germplasm was grouped into two subpopulations. The analysis of molecular variance (AMOVA) revealed that 53.3% of genetic variation existed within individuals. Relatively low population differentiation was recorded amongst the test populations indicated by the mean fixation index (Fst) value of 0.032. The Tanzanian pigeonpea germplasm collection was grouped into three major clusters. The clustering pattern revealed a lack of relationship between geographic origin and genetic diversity. This study provides a foundation for the selection of parental material for genetic improvement.
Tools to Tie: Flower Characteristics, VOC Emission Profile, and Glandular Trichomes of Two Mexican Salvia Species to Attract Bees
Authors: Giuliani Claudia , Giovanetti Manuela , Lupi Daniela , Mesiano Marco Palamara , Barilli Renata , Ascrizzi Roberta , Flamini Guido , Fico Gelsomina
Published: November 2020

A plant can combine physical and chemical tools to interact with other organisms. Some are designed for pollinator attraction (i.e., colors and volatile organic compounds-VOCs); others can act to discourage herbivores (i.e., non-glandular trichomes). Few studies fully address available tools in a single species; notwithstanding, this information can be pivotal in understanding new interactions out of the home range. We characterized flower traits, emission profiles of constitutive compounds from flowers and leaves, micro-morphology of the glandular trichomes, and listed flower visitors of two Mexican bird-pollinated Salvia species (S. blepharophylla and S. greggii), growing in an Italian botanical garden. Flowers were highly variable in their morphometric characteristics. In both species, four trichome morphotypes with similar histochemistry and distribution were documented for leaves and flowers except the calyx abaxial side. The vegetative emission profiles were qualitatively more complex than the floral ones; however, common compounds occurring in high relative percentages were β-caryophyllene and germacrene D. Floral bouquets were dominated by limonene and β-pinene in S. greggii and by 1,8-cineole in S. blepharophylla. Two potential (non-bird) pollinators were especially abundant: small bees belonging to the genus Lasioglossum and large bees belonging to the species Xylocopa violacea. Our study highlights the plasticity of these plants, as well as tools that can be conveniently used to establish novel interactions.
How Can Physiological Computing Benefit Human-Robot Interaction?
Authors: Roy Raphaëlle N. , Drougard Nicolas , Gateau Thibault , Dehais Frédéric , Chanel Caroline P. C.
Published: November 2020

As systems grow more automatized, the human operator is all too often overlooked. Although human-robot interaction (HRI) can be quite demanding in terms of cognitive resources, the mental states (MS) of the operators are not yet taken into account by existing systems. As humans are no providential agents, this lack can lead to hazardous situations. The growing number of neurophysiology and machine learning tools now allows for efficient operators’ MS monitoring. Sending feedback on MS in a closed-loop solution is therefore at hand. Involving a consistent automated planning technique to handle such a process could be a significant asset. This perspective article was meant to provide the reader with a synthesis of the significant literature with a view to implementing systems that adapt to the operator’s MS to improve human-robot operations’ safety and performance. First of all, the need for this approach is detailed regarding remote operation, an example of HRI. Then, several MS identified as crucial for this type of HRI are defined, along with relevant electrophysiological markers. A focus is made on prime degraded MS linked to time-on-task and task demands, as well as collateral MS linked to system outputs (i.e., feedback and alarms). Lastly, the principle of symbiotic HRI is detailed and one solution is proposed to include the operator state vector into the system using a mixed-initiative decisional framework to drive such an interaction.
Combining UAV-Based SfM-MVS Photogrammetry with Conventional Monitoring to Set Environmental Flows: Modifying Dam Flushing Flows to Improve Alpine Stream Habitat
Authors: Lane Stuart N. , Gentile Alice , Goldenschue Lucien
Published: November 2020

Setting environmental flows downstream of hydropower dams is widely recognized as important, particularly in Alpine regions. However, the required flows are strongly influenced by the effects of the physical environment of the downstream river. Here, we show how unmanned aerial vehicle (UAV)-based structure-from-motion multiview stereo (SfM-MVS) photogrammetry allows for incorporation of such effects through determination of spatially distributed patterns of key physical parameters (e.g., bed shear stress, bed grain size) and how they condition available stream habitat. This is illustrated for a dam-impacted Alpine stream, testing whether modification of the dam’s annual flushing flow could achieve the desired downstream environmental improvement. In detail, we found that (1) flood peaks in the pilot study were larger than needed, (2) only a single flood peak was necessary, (3) sediment coarsening was likely being impacted by supply from nonregulated tributaries, often overlooked, and (4) a lower-magnitude but longer-duration rinsing flow after flushing is valuable for the system. These findings were enabled by the spatially rich geospatial datasets produced by UAV-based SfM-MVS photogrammetry. Both modeling of river erosion and deposition and river habitat may be revolutionized by these developments in remote sensing. However, it is combination with more traditional and temporarily rich monitoring that allows their full potential to be realized.
Assessment of IMERG-V06, TRMM-3B42V7, SM2RAIN-ASCAT, and PERSIANN-CDR Precipitation Products over the Hindu Kush Mountains of Pakistan, South Asia
Authors: Hamza Ali , Anjum Muhammad Naveed , Masud Cheema Muhammad Jehanzeb , Chen Xi , Afzal Arslan , Azam Muhammad , Kamran Shafi Muhammad , Gulakhmadov Aminjon
Published: November 2020

In this study, the performances of four satellite-based precipitation products (IMERG-V06 Final-Run, TRMM-3B42V7, SM2Rain-ASCAT, and PERSIANN-CDR) were assessed with reference to the measurements of in-situ gauges at daily, monthly, seasonal, and annual scales from 2010 to 2017, over the Hindu Kush Mountains of Pakistan. The products were evaluated over the entire domain and at point-to-pixel scales. Different evaluation indices (Correlation Coefficient (CC), Root Mean Square Error (RMSE), Bias, and relative Bias (rBias)) and categorical indices (False Alarm Ration (FAR), Critical Success Index (CSI), Success Ratio (SR), and Probability of Detection (POD)) were used to assess the performances of the products considered in this study. Our results indicated the following. (1) IMERG-V06 and PERSIANN capably tracked the spatio-temporal variation of precipitation over the studied region. (2) All satellite-based products were in better agreement with the reference data on the monthly scales than on daily time scales. (3) On seasonal scale, the precipitation detection skills of IMERG-V06 and PERSIANN-CDR were better than those of SM2Rain-ASCAT and TRMM-3B42V7. In all seasons, overall performance of IMERG-V06 and PERSIANN-CDR was better than TRMM-3B42V7 and SM2Rain-ASCAT. (4) However, all products were uncertain in detecting light and moderate precipitation events. Consequently, we recommend the use of IMERG-V06 and PERSIANN-CDR products for subsequent hydro-meteorological studies in the Hindu Kush range.
Evaluating the Impact of the 2020 Iowa Derecho on Corn and Soybean Fields Using Synthetic Aperture Radar
Authors: Hosseini Mehdi , Kerner Hannah R. , Sahajpal Ritvik , Puricelli Estefania , Lu Yu-Hsiang , Lawal Afolarin Fahd , Humber Michael L. , Mitkish Mary , Meyer Seth , Becker-Reshef Inbal
Published: November 2020

On 10 August 2020, a series of intense and fast-moving windstorms known as a derecho caused widespread damage across Iowa’s (the top US corn-producing state) agricultural regions. This severe weather event bent and flattened crops over approximately one-third of the state. Immediate evaluation of the disaster’s impact on agricultural lands, including maps of crop damage, was critical to enabling a rapid response by government agencies, insurance companies, and the agricultural supply chain. Given the very large area impacted by the disaster, satellite imagery stands out as the most efficient means of estimating the disaster impact. In this study, we used time-series of Sentinel-1 data to detect the impacted fields. We developed an in-season crop type map using Harmonized Landsat and Sentinel-2 data to assess the impact on important commodity crops. We intersected a SAR-based damage map with an in-season crop type map to create damaged area maps for corn and soybean fields. In total, we identified 2.59 million acres as damaged by the derecho, consisting of 1.99 million acres of corn and 0.6 million acres of soybean fields. Also, we categorized the impacted fields to three classes of mild impacts, medium impacts and high impacts. In total, 1.087 million acres of corn and 0.206 million acres of soybean were categorized as high impacted fields.
Characterization and Analysis of Okoume and Aiele Essential Oils from Gabon by GC-MS, Electronic Nose, and Their Antibacterial Activity Assessment
Authors: Aghoutane Youssra , Moufid Mohammed , Motia Soukaina , Padzys Guy Stephane , Omouendze Linda Priscilia , Llobet Eduard , Bouchikhi Benachir , El Bari Nezha
Published: November 2020

Essential oil resins of Aucoumea klaineana (Okoume) and Canarium schweinfurthii (Aiele) species, of the Burseraceae family, were studied to investigate their bioactive constituents and their antibacterial activities. Aiele resin had a higher yield (6.86%) of essential oil than Okoume (3.62%). Twenty-one compounds for Okoume and eighteen for Aiele essential oil were identified using a gas chromatography-mass spectrometry (Gp-C-MS) technique. The main compounds identified in Okoume essential oil were benzenemethanol, α, α,4-trimethyl (28.85%), (+)-3-carene (3,7,7-trimethyl bicyclo[4.1.0]hept-3-ene) (17.93%), D-Limonene ((4R)-1-methyl-4-prop-1-en-2-ylcyclohexene) (19.36%). With regard to the Aiele essential oil, we identified (1R,4S)-1-methyl-4-propan-2-ylcyclohex-2-en-1-ol (26.64%), and 1-methyl-4-propan-2-ylcyclohex-2-en-1-ol (26.83%). Two strains of bacteria, Escherichia coli and Staphylococcus aureus, were used in antibacterial tests. S. aureus was found to be more sensitive to Okoume and Aiele essential oils, with a high inhibition zone ranging from 20 to 16 mm. In comparison, the inhibition zone ranged from 6 to 12 mm for E. coli. An electronic nose (e-nose) combined with pattern analysis methods such as principal component analysis (PCA), discriminant function analysis (DFA), and hierarchical cluster analysis (HCA) were used to discriminate the essential oil samples. In summary, the e-nose and GC-MS allowed the identification of bioactive compounds in the essential oil samples, which have a strong antimicrobial activity, with satisfactory results.
Behavioral, Physiological and EEG Activities Associated with Conditioned Fear as Sensors for Fear and Anxiety
Authors: Chien Jui-Hong , Colloca Luana , Korzeniewska Anna , Meeker Timothy J. , Bienvenu O. Joe , Saffer Mark I. , Lenz Fred A.
Published: November 2020

Anxiety disorders impose substantial costs upon public health and productivity in the USA and worldwide. At present, these conditions are quantified by self-report questionnaires that only apply to behaviors that are accessible to consciousness, or by the timing of responses to fear- and anxiety-related words that are indirect since they do not produce fear, e.g., Dot Probe Test and emotional Stroop. We now review the conditioned responses (CRs) to fear produced by a neutral stimulus (conditioned stimulus CS+) when it cues a painful laser unconditioned stimulus (US). These CRs include autonomic (Skin Conductance Response) and ratings of the CS+ unpleasantness, ability to command attention, and the recognition of the association of CS+ with US (expectancy). These CRs are directly related to fear, and some measure behaviors that are minimally accessible to consciousness e.g., economic scales. Fear-related CRs include non-phase-locked phase changes in oscillatory EEG power defined by frequency and time post-stimulus over baseline, and changes in phase-locked visual and laser evoked responses both of which include late potentials reflecting attention or expectancy, like the P300, or contingent negative variation. Increases (ERS) and decreases (ERD) in oscillatory power post-stimulus may be generalizable given their consistency across healthy subjects. ERS and ERD are related to the ratings above as well as to anxious personalities and clinical anxiety and can resolve activity over short time intervals like those for some moods and emotions. These results could be incorporated into an objective instrumented test that measures EEG and CRs of autonomic activity and psychological ratings related to conditioned fear, some of which are subliminal. As in the case of instrumented tests of vigilance, these results could be useful for the direct, objective measurement of multiple aspects of the risk, diagnosis, and monitoring of therapies for anxiety disorders and anxious personalities.
Nonlinear Complementary Filter for Attitude Estimation by Fusing Inertial Sensors and a Camera
Authors: Zheng Lingxiao , Zhan Xingqun , Zhang Xin
Published: November 2020

Using a standalone camera for pose estimation has been quite a standard task. However, the point correspondence-based algorithms require at least four feature points in the field of view. This paper considers the situation that there are only two feature points. Focusing on the attitude estimation, we propose to fuse a camera with low-cost inertial sensors based on a nonlinear complementary filter design. An implicit geometry measurement model is derived using two feature points in an image. This geometry measurement is fused with the angle rate measurement and vector measurement from inertial sensors using the proposed nonlinear complementary filter with only two parameters to be adjusted. The proposed nonlinear complementary filter is posed directly on the special orthogonal group SO(3). Based on the theory of nonlinear system stability analysis, the proposed filter ensures locally asymptotic stability. A quaternion-based discrete implementation of the filter is also given in this paper for computational efficiency. The proposed algorithm is validated using a smartphone with built-in inertial sensors and a rear camera. The experimental results indicate that the proposed algorithm outperforms all the compared counterparts in estimated accuracy and provides competitive computational complexity.
Synthesis of ZnO Nanorod Film Deposited by Spraying with Application for Flexible Piezoelectric Energy Harvesting Microdevices
Authors: Elvira-Hernández Ernesto A. , Romero-García Jorge , Ledezma-Pérez Antonio , Herrera-May Agustín L. , Hernández-Hernández Ernesto , Uscanga-González Luis A. , Jarvio-Cordova Víctor A. , Hurtado Gilberto , Gallardo-Vega Carlos , de León Arxel
Published: November 2020

Industry 4.0 and the Internet of Things have significantly increased the use of sensors and electronic products based on flexible substrates, which require electrical energy for their performance. This electrical energy can be supplied by piezoelectric vibrational energy harvesting (pVEH) devices. These devices can convert energy from ambient mechanical excitations into electrical energy. In order to develop, these devices require piezoelectric films fabricated with a simple and low-cost process. In this work, we synthesize ZnO nanorod film by a solvothermal method and deposit by spraying on ITO (indium-tin-oxide)/PET (polyethylene terephthalate) flexible substrate for a pVEH microdevice. The results of the characterization of the ZnO nanorod film using X-ray diffraction (XRD) confirm the typical reflections for this type of nanomaterial (JCPDS 36-145). Based on transmission electron microscopy (TEM) images, the size of the nanorod film is close to 1380 nm, and the average diameter is 221 ± 67 nm. In addition, the morphological characteristics of the ZnO nanorod film are obtained using atomic force microscopy (AFM) tapping images. The pVEH microdevice has a resonant frequency of 37 Hz, a generated voltage and electrical power of 9.12 V and 6.67 μW, respectively, considering a load resistance of 107.7 kΩ and acceleration of 1.5 g. The ZnO nanorod film may be applied to pVEH microdevices with flexible substrates using a low-cost and easy fabrication process.
Classification of Bee Pollen and Prediction of Sensory and Colorimetric Attributes—A Sensometric Fusion Approach by e-Nose, e-Tongue and NIR
Authors: Sipos László , Végh Rita , Bodor Zsanett , Zaukuu John-Lewis Zinia , Hitka Géza , Bázár György , Kovacs Zoltan
Published: November 2020

The chemical composition of bee pollens differs greatly and depends primarily on the botanical origin of the product. Therefore, it is a crucially important task to discriminate pollens of different plant species. In our work, we aim to determine the applicability of microscopic pollen analysis, spectral colour measurement, sensory, NIR spectroscopy, e-nose and e-tongue methods for the classification of bee pollen of five different botanical origins. Chemometric methods (PCA, LDA) were used to classify bee pollen loads by analysing the statistical pattern of the samples and to determine the independent and combined effects of the above-mentioned methods. The results of the microscopic analysis identified 100% of sunflower, red clover, rapeseed and two polyfloral pollens mainly containing lakeshore bulrush and spiny plumeless thistle. The colour profiles of the samples were different for the five different samples. E-nose and NIR provided 100% classification accuracy, while e-tongue > 94% classification accuracy for the botanical origin identification using LDA. Partial least square regression (PLS) results built to regress on the sensory and spectral colour attributes using the fused data of NIR spectroscopy, e-nose and e-tongue showed higher than 0.8 R2 during the validation except for one attribute, which was much higher compared to the independent models built for instruments.
The Influence of Mycorrhizal Fungi on the Accumulation of Sennosides A and B in Senna alexandrina and Senna italica
Authors: AlZain Mashail N. , AlAtar Abdulrahman A. , Alqarawi Abdulaziz A. , Mothana Ramzi A. , Noman Omar M. , Herqash Rashed N. , AlSheddi Ebtesam S. , Farshori Nida N. , Alam Perwez
Published: November 2020

Symbiotic arbuscular mycorrhizal fungi (AMF) play a major role in plant development, growth, and relationships with the environment through a change in the accumulation of secondary metabolites; hence, we planned to investigate AMF’s influence on sennoside A and B accumulation in Senna alexandrina (SA) and Senna italica (SI). Seeds of SA (S. alexandrina free of mycorrhizae) and SI (S. italica free of mycorrhizae) were planted in two types of soils: +mycorrhiza and—mycorrhiza. The plant leaves of SA, SI, S. alexandrina with mycorrhizae (SAM) and S. italica with mycorrhizae (SIM) were collected and extracted (with 85% methanol), and sennoside A and B content was evaluated by the HPLC–UV method. The antioxidant activity of SA, SI, SAM and SIM was evaluated by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods, while antimicrobial properties were evaluated by the minimum inhibitory concentration method (MIC). The AMF colonization was 85.66% and 85%, respectively, in the roots of SA and SI. The HPLC analysis showed a significant increase in (%) the content of sennoside A/sennoside B by 71.11/88.21, respectively, in SAM and 6.76/36.37 in SIM, which clearly indicated positive AMF effects. The DPPH/ABTS [The half maximal inhibitory concentration (IC50): 235.9/321.5 µg/mL] scavenging activity of SAM was comparatively higher and it also exhibited strong antibacterial action (MIC: 156.25 µg/mL), which supported the increase in sennoside content. This finding may be useful for further investigations of the symbiotic relation of mycorrhizal fungi with other plant species.
Numerical Modeling and Analysis of Concrete Slabs in Interaction with Subsoil
Authors: Cajka Radim , Marcalikova Zuzana , Bilek Vlastimil , Sucharda Oldrich
Published: November 2020

This article focuses on the analysis and numerical modeling of a concrete slab interacting with subsoil. This is a complex task for which a number of factors enter into the calculation, including the scope or dimension of the model, the non-linear solution approach, the choice of input parameters, and so forth. The aim of this article is to present one possible approach, which is based on a non-linear analysis and a three-dimensional computational model. Five slabs were chosen for modeling and analysis. The experiments involved slabs of 2000 × 2000 mm and a thickness of 150 mm, which were tested using specialized equipment. The slabs included a reinforced concrete slab, a standard concrete slab, and three fiber-reinforced concrete slabs. The fiber-reinforced slabs had fiber volume fractions of 0.32%, 0.64%, and 0.96%, which corresponded to fiber dosages of 25, 50, and 75 kg/m3. A reinforced concrete slab was chosen for the calibration model and the initial parametric study. The numerical modeling itself was based on a detailed evaluation of experiments, tests, and recommendations. The finite element method was used to solve the three-dimensional numerical model, where the fracture-plastic material of the model was used for concrete and fiber-reinforced concrete. In this paper, the performed numerical analyses are compared and evaluated, and recommendations are made for solving this problem.
Annoyance Based Vibro-Acoustic Comfort Evaluation of as Summation of Stimuli Annoyance in the Context of Human Exposure to Noise and Vibration in Buildings
Authors: Nering Krzysztof , Kowalska-Koczwara Alicja , Stypuła Krzysztof
Published: November 2020

This paper presents the issues of assessing the comfort of people staying indoors who are exposed to vibrations and material noise caused by vibrations of partitions like floors and walls (ground-borne noise). Current criteria in the evaluation of vibrational and acoustic comfort cannot be assessed in the context of the simultaneous occurrence of stimuli such as noise and vibration. Railway transport, including passenger and cargo transport, is becoming increasingly prevalent, and new railway lines are being planned for environmental reasons. Sometimes, there are changes in stimuli produced by existing railway lines. For example, high-speed trains appear on an old railway track. Such a situation appeared on the Central Railway Line in Poland, which is still used by old trains, yet its operator plans to raise their speed limits. The analysis of the problem of the simultaneous occurrence of stimuli presented in this paper was based on measurements performed in a residential building located near the Central Railway Main Line in the city Zawiercie. Noise and vibration as the analyzed stimuli in both cases meet comfort requirements, yet when exposure to two stimuli was considered, comfort may be at risk.
Learning Strategies at a Higher Taxonomic Level in Primary Education Students in the Digital Age
Authors: Aravena-Gaete Margarita , Campos-Soto María Natalia , Rodríguez-Jiménez Carmen
Published: November 2020

The education system must respond to the demands and needs of today’s society. To meet this demand, teachers must identify the degree of cognitive skills that our students possess through digital learning strategies that encourage the development of these superior skills because of the impact of technological resources on student motivation. To carry out this assessment, two types of strategy tests were applied to evaluate cognitive skills, one determining the student’s ability to create an opinion of their own based on ideas and visions of other authors (perspective analysis) and the other strategy test to distinguish the main elements of an information, identifying a general pattern (abstraction), which were reviewed with a task performance instrument (rubrics). A mixed methodology was used through a case study, with a selected and intentional sample of 34 students of the Primary Education Grade. The results show that elaborating questions that go deeper into a topic and labelling contents is not an easy task and that abstraction is one of the most complex skills to develop in students. It should be noted that, in practically all areas, men’s averages exceed those of women. Finally, the use of digital strategies must be incorporated as permanent routines and the relationship between technology and pedagogy allows for the management of learning and therefore increases higher level cognitive abilities.
Leading Proactivity in Innovative Startups: A Moderated Mediation Model
Authors: Martínez-Córcoles Mario , Zhu Xi
Published: November 2020

Despite the growing research interest in proactivity, little is known about the relational mechanisms that cultivate individuals’ proactivity in the workplace. This research aims to explore the leader–follower relational mechanisms leading to employee proactive performance in innovative startups. The sample consisted of 83 employees from eleven startups. Conditional process modeling was conducted to explore the background relational mechanisms of employee proactive performance. Employees with upward psychological safety (who felt safe to speak up and contribute in front of their leaders) were willing to go beyond their formal roles and job descriptions for the sake of the firm (challenging role orientation). In turn, this orientation predicted self-directed efforts and initiated better ways of doing their job (proactive performance). Under high levels of perceived uncertainty, upward psychological safety was a stronger predictor of proactive performance through a challenging role orientation. This study reveals that upward psychological safety is critical for enhancing employee proactivity at work, particularly under high uncertainty.