bluuebunny/crossref_metadata_2025 huggingface dataset:
Monocytes and macrophages: emerging mechanisms and novel therapeutic targets in pulmonary fibrosis
Authors: Perrot Carole Y. , Karampitsakos Theodoros , Herazo-Maya Jose D.
Published: September 2023

Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic pulmonary fibrosis (IPF), inhalational, environmental, or occupational exposures in genetically and epigenetically predisposed individuals trigger recurrent cycles of alveolar epithelial cell injury, activation of coagulation pathways, chemoattraction, and differentiation of monocytes into monocyte-derived alveolar macrophages (Mo-AMs). When these events happen intermittently and repeatedly throughout the individual’s life cycle, the wound repair process becomes aberrant leading to bronchiolization of distal air spaces, fibroblast accumulation, extracellular matrix deposition, and loss of the alveolar-capillary architecture. The role of immune dysregulation in IPF pathogenesis and progression has been underscored in the past mainly after the disappointing results of immunosuppressant use in IPF patients; however, recent reports highlighting the prognostic and mechanistic roles of monocytes and Mo-AMs revived the interest in immune dysregulation in IPF. In this review, we will discuss the role of these cells in the onset and progression of IPF, as well as potential targeted therapies.
Industrial Chain Disruption Events Monitoring with Deep Learning Methods: A Practical Application in China
Authors: Tang Huimin , Yuan Yuan , Gong Tianxiao
Published: September 2023

Globalization has made the industrial chain longer and more complex, resulting in greater vulnerability to emergencies, such as the COVID‐19 pandemic, earthquakes, and wars. Emergencies will lead to plant shutdowns, supply shortages, market blockades, and other risk events, leading to large‐scale supply chain disruption, also known as industrial chain disruption. The safety and stability of the industrial chain are the foundation of national economic stability. All countries attach great importance to risk monitoring leading to the interruption of the industrial chain. However, at present, the risk monitoring method of the industrial chain is mainly to screen out the risk events that may cause the industrial chain disruption from news by manually monitoring the news media. It is of great significance to establish an efficient automatic monitoring system for industrial chain disruption events (ICDE). In this paper, an ICDE monitoring model is proposed to identify ICDE automatically using deep learning technology. The ICDE monitoring model consists of an ICDE identification model and an ICDE correlation model. The former identifies risk events from online news through the Ernie model, while the latter matches risk events with industrial chain nodes through similar nodes and virtual nodes. Similar nodes refer to synonyms in industrial chain nodes. Virtual nodes refer to the words that appear in a large number in the news and do not exist in the industrial chain, but they form an inclusive relationship with the nodes of the industrial chain. Finally, the model is applied to the new energy vehicle industry chain as an example. The application results show that the model can monitor ICDE on each node of the industry chain in real time, and the identification accuracy of ICDE is 92%. Through the ICDE monitoring model, the national or local government can formulate measures to reduce industrial losses in time and track the risk status of the industrial chain in real time.
DNA Methylation Near DLGAP2 May Mediate the Relationship between Family History of Type 1 Diabetes and Type 1 Diabetes Risk
Authors: Johnson Randi K. , Ireton Amanda J. , Carry Patrick M. , Vanderlinden Lauren A. , Dong Fran , Romero Alex , Johnson David R. , Ghosh Debashis , Yang Fan , Frohnert Brigitte , Yang Ivana V. , Kechris Katerina , Rewers Marian , Norris Jill M.
Published: September 2023

Given the differential risk of type 1 diabetes (T1D) in offspring of affected fathers versus affected mothers and our observation that T1D cases have differential DNA methylation near the imprinted DLGAP2 gene compared to controls, we examined whether methylation near DLGAP2 mediates the association between T1D family history and T1D risk. In a nested case–control study of 87 T1D cases and 87 controls from the Diabetes Autoimmunity Study in the Young, we conducted causal mediation analyses at 12 DLGAP2 region CpGs to decompose the effect of family history on T1D risk into indirect and direct effects. These effects were estimated from two regression models adjusted for the human leukocyte antigen DR3/4 genotype: a linear regression of family history on methylation (mediator model) and a logistic regression of family history and methylation on T1D (outcome model). For 8 of the 12 CpGs, we identified a significant interaction between T1D family history and methylation on T1D risk. Accounting for this interaction, we found that the increased risk of T1D for children with affected mothers compared to those with no family history was mediated through differences in methylation at two CpGs (cg27351978, cg00565786) in the DLGAP2 region, as demonstrated by a significant pure natural indirect effect (odds ratio (OR) = 1.98, 95% confidence interval (CI): 1.06–3.71) and nonsignificant total natural direct effect (OR = 1.65, 95% CI: 0.16–16.62) (for cg00565786). In contrast, the increased risk of T1D for children with an affected father or sibling was not explained by DNA methylation changes at these CpGs. Results were similar for cg27351978 and robust in sensitivity analyses. Lastly, we found that DNA methylation in the DLGAP2 region was associated (

P
<
0.05

) with gene expression of nearby protein-coding genes DLGAP2, ARHGEF10, ZNF596, and ERICH1. Results indicate that the maternal protective effect conferred through exposure to T1D in utero may operate through changes to DNA methylation that have functional downstream consequences.
The Clinical Significance of the Derived Neutrophil‐to‐Lymphocyte Ratio in Differentiating Occult Psoriatic Arthritis from Psoriasis Alone
Authors: Yu Yingyuan , Huang Dawei , Jiang Yuxiong , Lu Jiajing , Cui Lian , Chen Rongfen , Li Ying , Shi Yuling
Published: September 2023

Background. Occult psoriatic arthritis (PsA) refers to a subset of psoriasis patients showing lesions on imaging but do not exhibit arthritis symptoms. Objective. This study was aimed to discover a simple biomarker that could be easily incorporated in clinical practice to identify occult PsA patients, defined as psoriasis patients with lesions on imaging but without arthritis symptoms, among silent psoriasis (PsO) patients, defined as psoriasis patients without any arthritis symptoms. Methods. A total of 149 silent PsO patients, including 83 PsO alone patients, defined as psoriasis patients without any arthritis symptoms and evidence of lesions on imaging, and 66 occult PsA patients, were enrolled in this cross‐sectional study, and they all underwent blood tests to determine hematological inflammation biomarkers. Results. Occult PsA patients had a higher derived neutrophil‐to‐lymphocyte ratio (dNLR) (1.6 (1.3–2.2) vs. 1.3 (0.9–1.8), p < 0.001), body mass index (BMI) (25.2 (23.7–28.1) vs. 24.0 (21.9–26.0), p = 0.002), diabetes mellitus (DM) rate (30.3% vs. 7.2%, p < 0.001), and nail involvement rate (65.2% vs. 41.0%, p = 0.003) than patients with PsO alone. A prediction nomogram was established, and the area under the curve (AUC) was 0.843. The sensitivity and specificity of the model for identifying occult PsA patients were 77.3% and 81.9%, respectively. Conclusion. Our findings suggest that dNLR is a valuable diagnostic biomarker for occult PsA, and our prediction nomogram could provide clinicians with a useful tool for differentiating occult PsA patients from PsO alone patients.
Supplementary Figure 1 from Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy
Authors: Davis Richard W. , Klampatsa Astero , Cramer Gwendolyn M. , Kim Michele M. , Miller Joann M. , Yuan Min , Houser Cassandra , Snyder Emma , Putt Mary , Vinogradov Sergei A. , Albelda Steven M. , Cengel Keith A. , Busch Theresa M.
Published: September 2023

Supplemental Figure 1. Growth Curves of Individual Mice Treated With Surgical Resection, Photodynamic Therapy, or Tumor Incisions
Marijuana and Cannabidiol Use Prevalence and Symptom Management Among Patients with Cancer
Authors: Brasky Theodore M. , Newton Alison M. , Conroy Sara , Adib Anita , Adley Neema C. , Strassels Scott A. , Hays John L. , Cooper Ziva D. , Wagener Theodore L. , Stevens Erin , Plascak Jesse J. , Krok-Schoen Jessica L.
Published: September 2023

Symptoms such as pain, nausea, and anxiety are common in individuals with cancer. Treatment of these issues is often challenging. Cannabis products may be helpful in reducing the severity of these symptoms. While some studies include data on the prevalence of cannabis use among patients with cancer, detailed data remain limited, and none have reported the prevalence of cannabidiol (CBD) use in this population.

Adult patients with cancer attending eight clinics at a large, NCI-designated Comprehensive Cancer Center completed a detailed, cannabis-focused questionnaire between 2021 and 2022. Eligible participants were diagnosed with invasive cancer and treated in the past 12 months. Summary statistics were calculated to describe the sample regarding cannabis use.

Approximately 15% (n = 142) of consented patients (n = 934) reported current cannabis use (defined as use within the past 12 months). Among which, 75% reported cannabis use in the past week. Among current cannabis users, 39% (n = 56; 6% overall) used CBD products. Current users reported using cannabis a median of 4.5 (interquartile range: 0.6–7.0) days/week, 2.0 (1.0–3.0) times per use/day, and for 3 years (0.8–30.0). Use patterns varied by route of administration. Patients reported moderate to high relief of symptoms with cannabis use.

This study is the most detailed to date in terms of cannabis measurement and provides information about the current state of cannabis use in active cancer. Future studies should include complete assessments of cannabis product use, multiple recruitment sites, and diverse patient populations.

Significance:

Clinicians should be aware that patients are using cannabis products and perceive symptom relief with its use.
Association between Serum C-Reactive Protein Concentrations and Risk of Cancer-Related Mortality in Patients Undergoing Hemodialysis: 10-Year Outcomes of the Q-Cohort Study
Authors: Uchida Yushi , Nakano Toshiaki , Hiyamuta Hiroto , Kitamura Hiromasa , Taniguchi Masatomo , Ooboshi Hiroaki , Tsuruya Kazuhiko , Kitazono Takanari
Published: September 2023

Introduction: Cancer constitutes a major source of morbidity and mortality among people undergoing hemodialysis (HD). A systemic inflammatory response is associated with the incidence and prognosis of cancer in the general population. However, the effect of systemic inflammation on cancer-related mortality in patients undergoing HD remains unclear. Methods: We analyzed 3,139 patients registered in the Q-Cohort Study, which is a multicenter, observational cohort study of patients on hemodialysis in Japan. The primary outcome was cancer-related mortality during a 10-year follow-up. The covariate of interest was serum C-reactive protein (CRP) concentrations at baseline. The patients were divided into tertiles based on their serum CRP concentrations at baseline (tertile [T] 1: ≤0.07; T2: 0.08–0.24; and T3: ≥0.25). The association between serum CRP concentrations and cancer-related mortality was calculated using the Cox proportional hazards model and the Fine-Gray subdistribution hazards model with non-cancer-related death as a competing risk. Results: During the 10-year follow-up, 216 patients died of cancer. In the multivariable analysis, the risk of cancer-related mortality in the highest tertile (T3) of serum CRP concentrations was significantly higher than that in the lowest tertile (T1) (multivariable-adjusted hazard ratio [95% confidence interval]: 1.68 [1.15–2.44]). This association remained consistent in the competing risk model, in which the subdistribution hazard ratio was 1.47 and the 95% confidence interval was 1.00–2.14 for T3 compared with T1. Conclusion: Higher serum CRP concentrations are associated with an increased risk of cancer-related mortality in patients undergoing maintenance HD.
Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in Mice
Authors: Torres-López Cristina , Cuartero Maria I. , García-Culebras Alicia , de la Parra Juan , Fernández-Valle María E. , Benito Marina , Vázquez-Reyes Sandra , Jareño-Flores Tania , de Castro-Millán Francisco J. , Hurtado Olivia , Buckwalter Marion S. , García-Segura Juan M. , Lizasoain Ignacio , Moro María A.
Published: September 2023

BACKGROUND:

Cognitive dysfunction is a frequent stroke sequela, but its pathogenesis and treatment remain unresolved. Involvement of aberrant hippocampal neurogenesis and maladaptive circuitry remodeling has been proposed, but their mechanisms are unknown. Our aim was to evaluate potential underlying molecular/cellular events implicated.

METHODS:

Stroke was induced by permanent occlusion of the middle cerebral artery occlusion in 2-month-old C57BL/6 male mice. Hippocampal metabolites/neurotransmitters were analyzed longitudinally by in vivo magnetic resonance spectroscopy. Cognitive function was evaluated with the contextual fear conditioning test. Microglia, astrocytes, neuroblasts, interneurons, γ-aminobutyric acid (GABA), and c-fos were analyzed by immunofluorescence.

RESULTS:

Approximately 50% of mice exhibited progressive post–middle cerebral artery occlusion cognitive impairment. Notably, immature hippocampal neurons in the impaired group displayed more severe aberrant phenotypes than those from the nonimpaired group. Using magnetic resonance spectroscopy, significant bilateral changes in hippocampal metabolites, such as myo-inositol or N-acetylaspartic acid, were found that correlated, respectively, with numbers of glia and immature neuroblasts in the ischemic group. Importantly, some metabolites were specifically altered in the ipsilateral hippocampus suggesting its involvement in aberrant hippocampal neurogenesis and remodeling processes. Specifically, middle cerebral artery occlusion animals with higher hippocampal GABA levels displayed worse cognitive outcome. Implication of GABA in this setting was supported by the amelioration of ischemia-induced memory deficits and aberrant hippocampal neurogenesis after blocking pharmacologically GABAergic neurotransmission, an intervention which was ineffective when neurogenesis was inhibited. These data suggest that GABA exerts its detrimental effect, at least partly, by affecting morphology and integration of newborn neurons into the hippocampal circuits.

CONCLUSIONS:

Hippocampal GABAergic neurotransmission could be considered a novel diagnostic and therapeutic target for poststroke cognitive impairment.
Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations
Authors: Broderick Joseph P. , Silva Gisele Sampaio , Selim Magdy , Kasner Scott E. , Aziz Yasmin , Sutherland Jocelyn , Jauch Edward C. , Adeoye Opeolu M. , Hill Michael D. , Mistry Eva A. , Lyden Patrick D. , Mocco J , Smith Elaine M. , Hernandez-Jimenez Macarena , Deljkich Emir , Kamel Hooman , Alemseged Fana , Bates Karen , Bhatt Nirav R. , Boltze Johannes , Campbell Bruce C.V. , Favilla Christopher , Fiorella David , Grotta James , Haddad Walid , Heidt Jeremy J. , Liebeskind David S. , Lightfoot Nathan , Jubin Ronald , Khatri Pooja , Lansberg Maarten G. , Lynch John , Margolin David H. , Nguyen Thanh N. , Nogueira Raul G. , Samaniego Edgar A. , Saver Jeffrey , Schwamm Lee H. , Sheth Kevin N. , Smith Wendy J. , Wadhwa Manish , Wakhloo Ajay K. , Wechsler Lawrence R. , Xiong Yunyun , Zachrison Kori S.
Published: September 2023

The Stroke Treatment Academic Industry Roundtable (STAIR) convened a session and workshop regarding enrollment in acute stroke trials during the STAIR XII meeting on March 22, 2023. This forum brought together stroke physicians and researchers, members of the National Institute of Neurological Disorders and Stroke, industry representatives, and members of the US Food and Drug Administration to discuss the current status and opportunities for improving enrollment in acute stroke trials. The workshop identified the most relevant issues impacting enrollment in acute stroke trials and addressed potential action items for each. Focus areas included emergency consent in the United States and other countries; careful consideration of eligibility criteria to maximize enrollment and representativeness; investigator, study coordinator, and pharmacist availability outside of business hours; trial enthusiasm/equipoise; site start-up including contractual issues; site champions; incorporation of study procedures into standard workflow as much as possible; centralized enrollment at remote sites by study teams using telemedicine; global trials; and coenrollment in trials when feasible. In conclusion, enrollment of participants is the lifeblood of acute stroke trials and is the rate-limiting step for testing an exciting array of new approaches to improve patient outcomes. In particular, efforts should be undertaken to broaden the medical community’s understanding and implementation of emergency consent procedures and to adopt designs and processes that are easily incorporated into standard workflow and that improve trials’ efficiencies and execution. Research and actions to improve enrollment in ongoing and future trials will improve stroke outcomes more broadly than any single therapy under consideration.
A Critique on the Current State of Research on the Social and Emotional Experiences of Gifted Individuals and a Framework for Moving the Field Forward
Authors: Rinn Anne N.
Published: September 2023

Despite multiple edited volumes dedicated to the various theories and conceptions of giftedness and talent that have been published over the past 40 years, the field of gifted education is still definitionally and paradigmatically fractured. These differences have led to a misunderstanding about the social and emotional experiences of gifted individuals that has further divided the field of gifted education. One purpose of this paper is to explain how varying definitions and paradigms of giftedness lead us to different answers and assumptions about the social and emotional experiences of gifted individuals, and the implications of those. The other purpose of this paper is to outline a framework for moving forward in thinking about and conducting research on the social and emotional experiences of gifted individuals.
Are Shared Values Valuable? Liberal Democracy and Human Rights among AUKUS and its Future Membership
Authors: Nishimura Yui , Tago Atsushi
Published: September 2023

Do shared values make a military partnership attractive to potential member countries and strengthen perceptions of that partnership's deterrent effects? While military cooperation attracts potential members through strategic benefits such as military capabilities, recent security cooperation initiatives like AUKUS emphasize liberal democratic values and human rights as their core values. This study focuses on Japan as a potential member of AUKUS in the Indo-Pacific region and explores how the Japanese public evaluates Japan's future participation in AUKUS and the agreement's anticipated deterrence effects. The results indicate that emphasizing liberal democratic values does not boost support for AUKUS or reinforce a belief in the agreement's ability to deter potential enemies. However, the findings highlight the connection between support for security cooperation and the expansion of membership, irrespective of regime types. In particular, the domestic audience exhibits selective attitudes towards South Korea, a democratic government that should be an important candidate for partnership. These findings suggest a cynical view among third-party audiences regarding the efficacy of shared values in security cooperation, as well as a double standard among the Japanese in shaping new security cooperation in the region.
Healthcare professionals’ knowledge, confidence and attitudes in relation to psychosis care: A systematic review
Authors: Chen Jenny , El-Den Sarira , Pham Lily , O’Reilly Claire L , Collins Jack C
Published: September 2023

Background:

Psychosis is a mental disorder that, despite its low prevalence, causes high disease and economic burden. Inadequate knowledge, lack of confidence and stigmatising attitudes of healthcare professionals (HCPs) may lead to suboptimal care.

Aim:

To review the literature exploring HCPs’ knowledge, confidence and attitudes in relation to psychosis care.

Method:

A systematic search was undertaken across three databases (MEDLINE, Embase, PsycINFO) using a search strategy encompassing the concepts: ‘healthcare professionals’, ‘knowledge, attitude, and confidence in care’ and ‘psychotic illnesses and symptoms’ to identify relevant records published from 1st January 2002 to 18th March 2022. Results were screened against predetermined inclusion and exclusion criteria by title and abstract, followed by full text. Data were extracted into tables and synthesised narratively.

Results:

Initially, 7,397 studies were identified. Following two-stage screening, 24 studies were eligible for inclusion. Of these studies, 16 explored attitudes, four explored knowledge and attitudes, one explored knowledge, one explored confidence, one explored attitudes and confidence in care and one explored all three constructs. Most HCPs in the included studies demonstrated stigmatising attitudes towards people with psychosis. Furthermore, certain HCPs, including nurses and general practitioners, demonstrated low levels of knowledge, while psychiatrists, occupational therapists, psychologists and nurses had low levels of confidence in caring for people with psychosis. Conversely, positive attitudes were also observed in some HCPs resulting from having acquaintances with lived experience of psychosis. The need for additional education and training to improve HCPs’ knowledge and confidence in relation to caring for people living with psychosis was identified.

Conclusions:

Most attitudes identified were negative and stemmed from stigma, while some were positive due to HCPs’ compassion and familiarity with psychosis. The level of knowledge and confidence identified were mostly suboptimal, and so further research is required to develop and evaluate tailored interventions to address this gap.
Police perspectives on the economic considerations of providing healthcare in short-term custodial settings in Australia
Authors: Brandenburg Caitlin , Crilly Julia , Thomas Stuart , Gardiner Paul , Kinner Stuart A , Heffernan Ed , Lincoln Cathy , Somerville Annabel , Davidson Peter , Wilson Daniel , Green David , Byrnes Joshua
Published: September 2023

Providing appropriate healthcare to people in short-term police custody settings (i.e. watch-houses) is challenging due to the complexity of detainee health needs and the limitations of the custodial environment. However, little is known about how detainee healthcare is managed in Australia, including economic considerations. This study had two aims: (1) to understand police perspectives on the costs associated with the delivery of healthcare to watch-house detainees in Queensland, Australia and (2) to scope the applicability of the Prison Healthcare Expenditure Reporting Checklist (PHERC) tool for the Australian watch-house context. The study employed an exploratory qualitative descriptive approach. A purposive sample comprised 16 watch-house staff from six regions in Queensland, Australia, interviewed between April and November 2021. A key finding was that police viewed healthcare expenditure as a major, but largely unavoidable cost for Australian watch-houses. Participants reported that direct expenditure comprised mostly of in-house healthcare services (of which there were a variety of models), but also costs of medication and health-related consumables. Indirect costs included costs of escorting and guarding detainees requiring transfer to hospital for health assessment and treatment. Participants reported that the PHERC was not applicable to the Australian watch-house context. Future research should explore the cost-effectiveness of different watch-house healthcare delivery models and how best to measure this.
Study on the pressure distribution of fall arrest belts in the static suspension and falling process
Authors: Chen Changjie , He Zebo , Wang Xinhou , Cui Yumei
Published: September 2023

The fall arrest belt as a piece of personal protective equipment is one of the primary methods of protection against falls. This paper uses pressure-sensitive paper to test the pressure distribution of six parts at different hanging points in static suspension and dynamic fall. The ordinary seat belt is improved by developing a wide–narrow changing belt, which promotes uniform pressure distribution. The results show that the front hanging point is better than the back hanging point, as it can minimize the pressure of the seat belt on the human body during static suspension. Using a wide–narrow changing belt to increase the contact area of the heavily compressed parts can significantly reduce the pressure and promote uniform pressure distribution. The variable coefficient of pressure distribution p of ordinary seat belts and wide–narrow changing seat belts decreased from 0.68 to 0.28. The force discrepancy in different parts fell from 143.7 to 34.8 N.
Peroxymonosulfate-based catalytic degradation of reactive dyes in real wastewater by Fe/N-codoped carbocatalysts loaded on carbon cloth
Authors: Yang Limeng , Yang Wenqiang , Fu Chengyu , Li Yujuan , Zhang Pengfei
Published: September 2023

This study simulated actual dyeing wastewater in dyeing factories with three types of dyeing wastewaters from laboratory cotton fabric dyeing to investigate the effects of catalyst and oxidant peroxymonosulfate (PMS) concentrations, pH level, and temperature on dye degradation in wastewater and determine the optimal conditions for dyeing wastewater treatment accordingly. The results demonstrated that the optimal conditions varied with the reactive dyes. Specifically, the optimal oxidant PMS concentration for degrading Reactive Yellow and Reactive Blue was 0.6 g/L, and that for degrading Reactive Red was 0.4 g/L. The optimal pH level for degrading Reactive Red and Reactive Blue was around 7.0, and that for degrading Reactive Yellow was about 5.0. The activation energy of the degradation and the mineralization degree of the three dyes were also discussed. Reactive Blue showed greater activation energy (47.0 kJ/mol) and a higher mineralization degree (81% chemical oxygen demand removal) than the other two dyes under optimal disposal conditions. The Fe/N-codoped carbocatalyst loaded on carbon cloth exhibited desirable reusability and good stability for the degradation of the three dyes. Mechanisms involved in their degradation were analyzed through X-ray photoelectron spectroscopy, focusing on N species, Fe-N binding, and C=C and C–N active components in the Fe/N-codoped carbocatalyst. Electron paramagnetic resonance experiments demonstrated that both the radical and non-radical pathways were accountable for the degradation of the three dyes, primarily the non-radical pathway. This study may contribute to the application of activated PMS for practical dyeing wastewater treatment.
Online Platform Use and Performance Among Listed Tourism Companies in China
Authors: Tian Jiaxin , Ma Jing
Published: September 2023

This paper applies information dissemination theory, consumer information behavior theory, signaling theory, and value co-creation theory to investigate the effects of companies’ online platform operations from a tourism company perspective. We gathered data from 51 listed tourism companies in China between 1992 and 2022 to test these impacts. Results showed that using online platforms could improve listed tourism companies’ performance, but not all platforms played the same role. Of the three online platforms we tested, official websites and WeChat accounts had significant positive influences on listed tourism companies’ performance; Weibo had no effect. Group research revealed that online platforms most effectively enhanced hotels’ performance, followed by comprehensive tourism companies. Resource tourism companies received no obvious impact.
Contributions of Muslim medieval scholars to psychology
Authors: Ansari Sameer , Iqbal Naved
Published: September 2023

Psychology has been the significant discipline since the time of antiquity which becomes more consolidated during the medieval age of Islam. It had a strong foundation in the professional writings of polymaths from the Islamic Middle Ages that were eventually transmitted to the West. However, the unique psychological contributions of these medieval polymaths remained largely unexplored. Despite the growing interest in their work, which is partly due to Islamic psychology, only a handful of them have been investigated for their unique psychological contributions, and a complete examination of psychological work has not been done, separately from an Islamic perspective. The majority of them have only been examined in terms of their medical value, neglecting psychological issues in their all-encompassing approaches to care. Therefore, it was quintessential to extensively explore all those scholars who contributed to the various fields of psychology and to fill a gap of information that has been left by the previous researchers.
Components of Valid Learning Media Assessments
Authors: McCarthy Tessa , Anderson Dawn , Emerson Robert Wall
Published: September 2023

Introduction

The learning media assessment (LMA) process is the mechanism professionals use to determine a student's optimal learning and reading media. Currently, no tool has been validated for the purpose of conducting the LMA process.

Methods

A Delphi approach was used whereby a panel of identified experts in the LMA process went through iterative phases recommending items to be included in the LMA process and voting on keeping, changing, or deleting items until a final list of agreed upon items was established.

Results

At the completion of five rounds of voting and amending items, the final list of agreed upon items included 2 general goals, 66 items, and 18 acceptable modifications to the LMA process. The items to be included in an LMA process were categorized into logistical items to be noted (9 items), LMA procedural characteristics (11 items), materials to be used (2 items), information to be gathered (20 items), student medical/visual characteristics (8 items), student reading or academic characteristics (10 items), and student technology and literacy tool use (6 items). Eighteen acceptable modifications or adjustments that could be made to assessment procedures were also agreed upon.

Discussion

The framework of what is critical in the LMA process, as shown in this Delphi study, can be used to assess the validity of LMA tools.

Implications for Practitioners

Practitioners can use the framework built by this Delphi process to evaluate the validity of LMA tools they use. Practitioners can assess the tools they use by asking if all the validated content areas are addressed, if validated procedures are being followed, and if validated accommodations are in place.
Impact of a school-based social skills training program on parent–child relationships and parent attitudes toward school
Authors: Slotkin Rebecca , Bierman Karen L. , Jacobson Linda N.
Published: September 2023

Developmental research suggests that peer rejection has negative spillover effects which strain parent–child relationships and parent attitudes toward the child’s school. This study tested whether a school-based social skill training program could reverse these effects and improve parent–child closeness and parent attitudes toward the school. Participants included 217 children who were rejected by peers (57% White, 17% Black, 20% Latinx, 5% multiracial; 68% male; Mage = 8.1 years old) identified with sociometric social preference scores and randomized to intervention or control groups. Parents rated parent–child closeness and parent attitudes toward school at the start and end of the intervention year. Multilevel path analyses indicated that intervention improved parent–child closeness and, for children in the older grade levels only, enhanced parent attitudes toward the school. Additional analyses revealed that intervention effects on parent–child closeness were direct whereas effects on attitudes toward school were mediated by intervention-related increases in teacher support and peer liking. Implications for intervention design and future research are discussed.
Structural features in classical and jazz studio lessons
Authors: Burwell Kim
Published: September 2023

The purpose of this study was to investigate broad structural divisions in advanced studio lessons, characterising and comparing them, and considering their implications beyond the context of the studio. The study took a microethnographic approach to the observation of two undergraduate studio lessons, one classical and one jazz, given by expert performer-teachers. Structures were identified by seeking patterns of behaviour in terms of performance and lesson dialogue, along with discourse markers that might signify changes of focus or trajectories of action. A common feature for the two lessons was a series of episodes focused on student performance, with behavioural patterns changing for episodes reflecting on it. Contextual episodes emerged as the outstanding feature of the jazz studio lesson. It is argued that contrasts between the two lessons might be linked to the cultural traditions implied in each, and that such studies can contribute to research-informed studio practices by provoking and supporting the ongoing development of excellence in the studio.
A new compression stocking with well-defined pressure—a randomized controlled pilot study
Authors: Källman Ulrika , Fallenius Melina , Bååth Carina
Published: September 2023

Background

To evaluate an innovative class I compression stocking with predetermined uniform pressure in comparison to a graduated class III compression stocking system, regarding edema reduction, interface pressure, and patient comfort.

Method

Twenty-five patients with chronic venous disease, were randomized: 12 to investigational stocking, 13 to comparator stocking. Data collected at baseline and after 14 days.

Results

Edema was significantly equal reduced to follow-up; mean −129.0 cm3 (SD 105; p = .004, Class I) and −223.7 cm3 (SD 120; p = .002, Class III), respectively. The investigational stocking lost significantly less compression pressure than the comparator stocking ( p ≤ .013). Participants in both groups perceived significant improvement regarding leg heaviness, leg swelling, and feelings of tightness and tingling ( p ≤ .016).

Conclusion

The innovative investigational class I stocking appears to offer similar edema reduction and benefits to the comparator class III stocking. However, a larger and prolonged study is required. The study was registered in the ISRCTN-registry, ISRCTN17356077, https://www.isrctn.com/ISRCTN17356077 .
Disneyland in Hong Kong: American image, glocally renowned
Authors: Bafagih Lujain , Wise Nicholas
Published: September 2023

Disney is one of the world’s largest global companies and a symbol of American image and consumerism. Disneyland is a well-known attraction with locations found around the world in the United States, Europe, and Asia. Disneyland’s Hong Kong location opened to the public in 2005 with some difficulties. As a Western attraction and entertainment enterprise operating in a foreign location, many were skeptical of how this would work given different perspectives when it comes to operating a business and satisfying consumer appeal in the local market. This viewpoint paper focuses on image and glocalization and challenges us to consider the role and significance of entertainment and event attractions. These will create and leverage diverse impacts, but we need to consider the impact of these attractions locally and culturally, as this will play an integral role in the competitiveness of the site or attraction.
Expansion of plasma MicroRNAs over the first month following human stroke
Authors: Edwardson Matthew A , Shivapurkar Narayan , Li James , Khan Muhib , Smith Jamal , Giannetti Margot L , Fan Ruzong , Dromerick Alexander W
Published: September 2023

Few have characterized miRNA expression during the transition from injury to neural repair and secondary neurodegeneration following stroke in humans. We compared expression of 754 miRNAs from plasma samples collected 5, 15, and 30 days post-ischemic stroke from a discovery cohort (n = 55) and 15-days post-ischemic stroke from a validation cohort (n = 48) to healthy control samples (n = 55 and 48 respectively) matched for age, sex, race and cardiovascular comorbidities using qRT-PCR. Eight miRNAs remained significantly altered across all time points in both cohorts including many described in acute stroke. The number of significantly dysregulated miRNAs more than doubled from post-stroke day 5 (19 miRNAs) to days 15 (50 miRNAs) and 30 (57 miRNAs). Twelve brain-enriched miRNAs were significantly altered at one or more time points (decreased expression, stroke versus controls: miR-107; increased expression: miR-99-5p, miR-127-3p, miR-128-3p, miR-181a-3p, miR-181a-5p, miR-382-5p, miR-433-3p, miR-491-5p, miR-495-3p, miR-874-3p, and miR-941). Many brain-enriched miRNAs were associated with apoptosis over the first month post-stroke whereas other miRNAs suggested a transition to synapse regulation and neuronal protection by day 30. These findings suggest that a program of decreased cellular proliferation may last at least 30 days post-stroke, and points to specific miRNAs that could contribute to neural repair in humans.
Theorizing the Costs of Self-Service Technologies and Co-Creation by Design
Authors: Darmody Aron , Zwick Detlev
Published: September 2023

In this commentary we explore how, in a market system that increasingly demands the participation of consumers as co-creators through self-service technologies, these technologies pose significant challenges to various consumers. We call this increase in demand the ‘everyday-ification’ of co-creation and consider its effect on consumers who are either unwilling or unable to co-create value. We look at how marketers are motivated to persistently replace human labor with technologies, not to primarily benefit consumers, but to discipline consumer labor and to maximize profits and shareholder value. Through this lens we examine five key issues with self-service technologies. First, we discuss how costs and benefits associated with self-service technologies are unequally allocated, before addressing how consumers’ choices are managed, consumers’ rising sense of powerlessness and increased vulnerabilities, consumers’ service failure responsibilization, and the cybernetic bureaucracy of life through self-service technologies.
Engineering students knowledge level on renewable energy resources: Bangladesh military engineering institute context
Authors: Rabby Md Insiat Islam , Uddin Md Wasi , Tarequl Islam Mohammad , Paul Dipto , Islam Fabliha
Published: September 2023

The aim of this study is to determine the Engineering students’ knowledge on Renewable Energy (RE) resources. An online survey through proving Google form was conducted by using descriptive methodology. The participants for the survey were the engineering undergraduate students from Military Institute of Science and Technology (MIST), Dhaka, Bangladesh. A set of e-questionnaire with 19 items including 4 demographic and 15 knowledge measuring items was developed to collect data from the MIST undergraduate students. A total of 153 students responded to the survey. The demographic results indicated that male students of first and third study year with 20 to 30 years of age range from mechanical or industrial and production-engineering fields of study are the maximum respondents to the survey of this study. The main findings of the study highlighted that engineering students at MIST possess a higher level of understanding about various aspects of renewable energy, including solar energy, geothermal energy, wind energy, biogas energy, laws and policies of renewable energy (RE), establishment of RE, sources of information for RE, and the application of renewable energy in Bangladesh. Since the mean score for the questions was 3.72, reflecting a knowledge level between neutrality and agreement, the majority of the students responded positively to all the questions, indicating their strong grasp of these topics. The results also revealed that female students had a good understanding of renewable energy compared to male students, with an average score of 3.83 for females and 3.69 for males. Additionally, the study found that 3rd-year students displayed the highest level of understanding, while 1st-year students exhibited the lowest level of comprehension regarding renewable energy resources.
On the nature, predictors, and outcomes of work passion profiles: A comparative study across samples of Indigenous and non-Indigenous Australian employees
Authors: Morin Alexandre JS , Gillet Nicolas , Chénard-Poirier Léandre-Alexis , Craven Rhonda G , Mooney Janet , Magson Natasha , Vallerand Robert J
Published: September 2023

Based on the dualistic model of passion, we conducted person-centered analyses to assess how harmonious and obsessive passion for work combine within distinct profiles of employees and document the associations between these profiles and theoretically relevant predictors and outcomes. We also investigate whether the nature of these profiles, and their associations with predictors and outcomes, differs between samples of Australian Indigenous ( N = 591; 66.0% female, Mage = 41.87) and non-Indigenous ( N = 605; 56.0% female, Mage = 44.79) employees. Our results uncovered four profiles, which were replicated across both samples of employees: Harmonious Passion Dominant, Obsessive Passion Dominant, Mixed Passion-Obsessive Passion Dominant, and Low Passion. Role ambiguity and job overload were found to be related to employees’ likelihood of profile membership in a way that was similar across both samples. Finally, psychological well-being and resilience at work differed as a function of profile membership in a way that was replicated across samples. In addition to the theoretical implications for research on work passion, these results clearly highlight how work passion has highly similar implications for Indigenous and non-Indigenous Australian employees.

JEL Classification: I3 Welfare, Well-Being, and Poverty
Recapturing the Bugsy Malones
Authors: Molloy Ciara
Published: September 2023

In the late 1970s, a criminal-based youth subculture known as the Bugsy Malones emerged in inner-city Dublin. Through the use of oral history interviews, this article avails of ‘proximate voices’ to shed light on the Bugsy Malones’ socio-economic background, their individual and group characteristics, and the rise of a subcultural mythology because of the involvement of Gerry ‘The Monk’ Hutch (a well-known Irish figure linked to organised crime) with the subculture. These proximate voices comprise n = 10 individuals who encountered the Bugsy Malones in a personal or professional capacity and shared lived experiences, physical spaces and/or interests with them. By capturing such voices, the article transcends caricatured press coverage and generates enhanced insight into this largely forgotten subculture.
Ultimate Load-Bearing Capacity of Rigid Two-Way Pavements Placed on Geosynthetic-Supported Soil Embankment
Authors: Manna Debashis , Santhoshkumar Gunasekaran , Ghosh Priyanka
Published: September 2023

This study investigates the ultimate load-bearing capacity of rigid two-way concrete pavements placed on conventional and reinforced soil embankments using upper-bound limit analysis (UBLA). In the presence of the median strip, upper-bound solutions of rigid pavements resting on reinforced embankments did not draw much attention from previous researchers. Therefore, a rigorous UBLA is performed, adopting the multi-block failure mechanism for the intended purpose. The true upper-bound solution is achieved by satisfying the conditions of geometric compatibility and kinematic admissibility. The effects of the proximity of dual carriageways and embankment slopes on the load-bearing capacity of pavements are expressed in relation to interaction factors. The critical spacing beyond which the proximity effect ceases to exist is estimated for different slope angles of the embankment. A parametric investigation is performed to understand the influence of various soil parameters, embankment geometry, and layers of reinforcement. A notable improvement in the performance of two closely spaced rigid pavements can be observed by providing additional layers of reinforcement. The current outcomes are sensible and match well with the existing investigations.
Predicting University Campus Parking Demand Using Machine Learning Models
Authors: Paudel Sohil , Vechione Matthew , Gurbuz Okan
Published: September 2023

Parking demand at university campuses has been an issue for decades and is gradually increasing each year. With limited capacity, space, and funds to expand parking facilities, there is a dire need to better understand parking behavior on a university campus so that universities can better utilize the limited resources available. One methodology that has been used by Metropolitan Planning Organizations to predict traveler behavior is known as travel demand modeling, where the most common modeling technique is a four-step procedure that utilizes socioeconomic data to predict current and future traffic volumes in a network (e.g., a city). This study focuses primarily on the trip generation step, and The University of Texas at Tyler campus was used as a case study. First, each parking lot on campus was assigned to a parking demand zone (PDZ) based on its proximity to classroom buildings, and the hourly arrival demand for each PDZ was measured using pneumatic tube counters. The course schedule and floor space utilization data for each building on campus were then extracted as input parameters to predict the parking demand at each PDZ. A linear regression model and two artificial neural network (ANN) frameworks were developed. One ANN model was recommended, as it had an R-squared value of 0.846. From the selected ANN model, an equation has been extracted, which has the potential to be used by course schedulers to modify the course schedule to better mitigate parking demand on campus without the need to develop new parking facilities.