bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH MODEL PEMBELAJARAN BERBASIS PROYEK TERHADAP KETERAMPILAN PROSES SAINS SISWA KELAS VII
Authors: Sari Maya Puspita , Amilda Amilda , Nawawi Sulton
Published: August 2019

This research aims to know the influence of the application of Project-Based Learning model do the Science Process Skills in environmental management material in VII class. Design research uses the posttest-only control design with quasi experiment method. The sample is 70 students. Based on the results of the analysis of the process of science skills, students indicated that the implementation of learning using project-based learning model is better than the conventional learning model. This can be seen in the calculation of test-t process skills science indicates that the Ha received and H0 is rejected. The results of the analysis of the average score of the science process skills thoroughly indicators in class experiments reached 2,87 with good criteria and in science process skills while students are in control class is 1,73 with enough criteria that means the science process skills grade experiment higher than science process skills class control. Based on the foregoing, Project-Based Learning model influence on Science process skills in environmental management material in VII Class.
PENGARUH INTEGRASI NILAI-NILAI ISLAM MELALUI PENDEKATAN IMAN DAN TAQWA (IMTAQ) PADA HASIL BELAJAR SISTEM REPRODUKSI MANUSIA DI MAN 2 KOTA BANDUNG
Authors: Yusuf Iwan Ridwan , Ukit Ukit , Paujiah Epa
Published: August 2019

Basically, education is a structured and systematic pattern that aims to improve human civilization, including biology teaching which is expected to contribute to the improvement of student behavior. Therefore, it is necessary to integrate religious values ​​as an important part in biology lessons. This research aims to know the effect of applying faith and taqwa (IMTAQ) approach to Biology learning in improving meaningful learning, with learning outcomes in the form of conceptual mastery and affective improvement. The research was conducted by using quasi experimental method, which is expected to describe phenomenon, occurrence, and causal relationship as the impact of integritation value of religious on biology subjects in the school of MAN 2, Bandung. In the research focus, it is assumed that teachers have the ability to integrate general science materials with Islamic values. The results showed that the integration of Islamic values ​​through IMTAQ approach can improve the process and the students learning outcomes, significantly. Used of this approach can also improve teacher performance with three reasons; 1) learning time more effective and efficient, 2) learning more focused on analysis of study of general and religious knowledge, and 3) learning activities more controlled. Through this model, the acquisition of learning outcomes has increased the mastery of significant student concepts, as evidenced by the increasing grade of students of class XI IPA from pre-test (36) and post-tests (74) results, with N-Gain 0.58 (medium category). The average post-test score indicates that 80% have reached of KKM (70), whereas affective indicator is 4.24% (high qualification). This study demonstrates that the integration of Islamic values ​​through an approach of faith and taqwa in biology learning can improve the meaningfulness of learning, and similar concepts can be implemented in other subjects and other schools.
HUBUNGAN KOMPONEN USAHA MENTAL (UM) DAN MENERIMA MENGOLAH INFORMASI (MMI) PADA PROSES PEMBELAJARAN BIOLOGI
Authors: Putri Iffa Ichwani
Published: August 2019

Mental effort is the ability of students to face the existing learning environment. Mental effort will affect Extranous Cognitive Load (ECL). ECL can affect the ability to receive and process student information (MMI). MMI will affect the cognitive work memory of students in storing and processing data. This study aims to determine the relationship between UM and MMI of students in biology learning. This research is a descriptive study, with a sample of high school class XI students in Pekanbaru City who took excretory system material learning. The results showed that the UM scores of students were in the very low category which showed that the ECL of students was in the low category. The MMI value obtained by students is in a fairly good category. The correlation between UM-MMI shows an inverse relationship. This shows that the low UM can increase the MMI value and can support a decrease in the cognitive load of students in the learning process.
PENGARUH NATRIUM SIKLAMAT TERHADAP HISTOPATOLOGI ORGAN MENCIT (Mus musculus) DAN SUMBANGSIHNYA PADA MATERI STRUKTUR DAN FUNGSI JARINGAN HEWAN DI SMA/MA
Authors: Habisukan Ummi Hiras
Published: August 2019

Sweeteners are one of the components which are often added to foodstuffs. Synthetic sweetenersare widely used in the society is sodium cyclamate. The purpose of this study was to determine thesodium cyclamate on the histological structure of the glomerulus of mice (Mus musculus). Thisresearch used 12 male mice (Mus musculus) with Completely Randomized Design (CRD) so thereare 4 groups (control, PI: 0,55 mg/grbb, p2: 1,1 mg/grbb, and p3: 1,65 mg/grbb) with 3 replicationsfor 24 days. Parameters observed were edema and comparison of area glomerulus with Bowmancapsule. The result showed that sodium cyclamate had effect to edema and tended to areaglomerulus with Bowman capsule comparization. Based on the research could be concluded thatsodium cyclamate had effect to renal histopathology. This research will be used as media inlearning process.
PENGEMBANGAN MODUL INQUIRY TERBIMBING BERMUATAN NILAI/KARAKTER UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DAN SIKAP PESERTA DIDIK PADA MATERI JAMUR KELAS XI
Authors: Wigati Indah
Published: August 2019

This study aims to produce a product that is a guided Inquiry module that contains values / characters. This research is a development research developed by Borg & Gall. Data analysis techniques using N-gain score, independent t test and MANOVA test. Product development validation is carried out by material experts, educational media value / character experts. The subjects of this study were students of class X MA Al-Fattah Palembang. Research instruments include modules that are integrated in values / characters, in which there are critical thinking questions and values / characters. Measurement of aspects of critical thinking according to Fascione and attitude based on an integrated questionnaire values / characters according to Einstein consisting of five values / characters namely religious, educational, socio-political, intellectual and practical values. The results of the product research are in the form of modules according to experts "good and" very good ". Learning by using a module shows an increase in the level of critical thinking (average gain score is 0.41), attitude with the value / character: moderate religious value (average score score 0.45), moderate education value (average score score 0.30), moderate socio-political value (average score score 0.32), moderate intellectual value (average score score 0.36) and moderate practical value (average score score 0.35). The Manova test shows that the Sig value is) .00.
PENGEMBANGAN ALAT PERAGA KIT UJI FOTOSINTESIS UNTUK MENINGKATKAN AKTIVITAS BELAJAR SISWA KELAS VIII-6 DI MTSN 1 BANDA ACEH TAHUN AJARAN 2018/2019
Authors: Harahap Nur Mahni
Published: August 2019

The purpose of this study was to determine the increase in learning activities of students of class VIII-6 with the use of KIT photosynthesis test at MTsN 1 Banda Aceh. The method used in this study is the research and development (R&D) method. The location of the study was carried out in the MTsN 1 Science Laboratory at Pocut Baren street number 114 Banda Aceh. This research was  conducted in odd semester academic Year 2018/2019 on 01 to 08 November 2018. The instrument in this study is the observation sheet. Data analysis in this study used descriptive statistics, percentage. The results of this study are the use of KIT teaching a photosynthetic test can improve the learning activities of students of class VIII-6 at MTsN 1 Banda Aceh.
PEMANFAATAN AMPAS TEBU DALAM MENINGKATKAN PERTUMBUHAN JAMUR TIRAM PUTIH (Pleurotus ostreatus) DI KOTA PALEMBANG DAN SUMBANGSIHNYA PADA MATA PELAJARAN BIOLOGI DI SMA
Authors: Hapida Yustina
Published: August 2019

Sugar cane organic waste including biomass waste which has a high lignocellulose content, good for mycelium growth so that it can be used as a medium for the growth of Jamur Tiram Putih (Pleurotus ostreatus). This study aims to determine the amount of ampas tebu can increase the growth of Jamur Tiram Putih (Pleurotus ostreatus).  The results of the studied Observation After 24th day  inoculated Jamur Tiram Putih (Pleurotus ostreatus), the addition of ampas tebu to the medium only affect the growth of mycelium . The dose of ampas tebu waste  added to the medium are 150 gr, 250 gr, and 350 gr. At pH 6,5, temperatures range 22-25 oC, humidity 72 % and ampas tebu dose 350 gr can increased mycelium of Jamur  Tiram Putih (Pleurotus ostreatus) growth.
Analisis Kepuasan Pengguna Terhadap Penerapan Simak Online Menggunakan Metode End User Computing Satisfaction (EUCS) (UIN Raden Fatah Palembang)
Authors: Erlika Yeni , Wijaya Freddy Kurnia , Santi Rusmala
Published: August 2019

Penggunaan simak online perlu dilakukan review untuk mengukur tingkat kepuasan pengguna. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pengguna simak online dengan menggunakan pendekatan model kepuasan pengguna akhir komputer EUCS yang berfokus pada kepuasan pengguna yang mencakup lima dimensi; content, accuracy, format, ease of use, timeliness. Data dalam penelitian ini dikumpulkan dengan menggunakan kuesioner yang disebarkan kepada 390 responden terdiri dari dosen dan mahasiswa/i di Universitas Islam Negeri raden Fatah Palembang. Hasil dari penelitian ini adalah tingkat kepuasan pengguna simak online sebesar 13% merasa sangat puas, 44% merasa puas, 34% merasa cukup puas, 9% merasa tidak puas, 1% merasa sangat tidak puas. Hasil penelitian ini sebagai masukan bagi Universitas Islam Negeri Raden Fatah Palembang khususnya untuk simak online dikaitkan dengan lima (5) variabel yang ada masih harus dan terus ditingkatkan lagi. Tingkat kepuasan pengguna akan mempengaruhi kesuksesan dalam penerapan sistem informasi akademik.
Sistem Informasi Inventaris Barang Pada Badan Pendapatan Daerah Provinsi Sumatera Selatan
Authors: Hastomo Panji , Santi Rusmala , Kadafi Muhamad
Published: August 2019

Sistem Informasi Inventaris Barang Pada Badan Pendapatan Daerah Provinsi Sumatera Selatan adalah sebuah sistem yang berbasis web dengan jaringan intranet dengan tujuan untuk mempermudah pengelolaan barang yang dimiliki oleh Badan Pendapatan Daerah Provinsi Sumatera Selatan dari mulai pengajuan permohonan hingga pengelolaan barang. Dengan menggunakan sistem ini diharapkan dapat membantu dan menghasilkan sebuah informasi untuk mencapai tujuan dari fungsi pengelolaan inventaris yang baik. Sistem yang dibuat berbasis intranet yang bertujuan untuk memudahkan proses pengelolaan inventarisasi yang hanya bisa dilakukan di lingkungan kerja Badan Pendapatan Daerah Provinsi Sumatera Selatan dari bagian pimpinan hingga ke lapisan unit kerja. Sistem Informasi Inventaris ini mencakup barang yang bergerak dan tidak bergerak yang meliputi peralatan dan perlengkapan kantor seperti peralatan elektronik, perlengkapan furniture, peralatan mesin, mobil dan sepeda motor. Proses yang ada pada sistem ini dimulai dari pengelolaan berkas permohonan pengadaan, perbaikan, mutasi, dan penghapusan. Serta laporan inventaris barang yang terkait dengan proses pengelolaan barang.
Sistem Informasi Distribusi Produk Paint Otomotif Menggunakan Metode DRP (Distribution Requirements Planning) Berbasis Web (Studi Kasus: CV. Catur Pandawa Maju Bersama Palembang)
Authors: Yuliarti Selly , Ruliansyah Ruliansyah , Jaya Irfan Dwi
Published: August 2019

CV. Catur Pandawa Maju Bersama merupakan perusahaan yang bergerak di bidang bisnis retail thinner dan cat yang aktivitas perusahaan mencakup penjualan thinner dan cat, baik secara tunai maupun kredit. Prosedur penjualan cash lebih sederhana dibandingkan penjualan secara kredit. Karena prosedur penjualan secara cash semua transaksi dilakukan langsung di perusahaan tersebut. Permasalahan yang terjadi pada sistem yang sedang berjalan yaitu belum sepenuhnya menggunakan fasilitas teknologi informasi untuk lebih mempermudah proses pendistribusian dan dalam proses pembelian masih dilakukan dengan cara pencatatan ke buku seperti data pemasukan dan pengeluaran barang berupa nota dalam proses distribusi. Metode perhitungan yang digunakan DRP (Distribution Requirement Planning) dan menggunakan perancangan Data Flow Diagram (DFD), metode pengembangan sistem waterfall, dan menggunakan bahasa pemrograman PHP. Data yang diolah pada sistem distribusi berupa data yaitu: data jenis barang, data salesman, data toko, data harga toko, data stok barang (barang masuk dan barang keluar) dan laporan yang dihasilkan berupa laporan penjualan, keuangan, dan stok barang. Sistem ini dibangun dapat mempermudah pihak CV. Catur Pandawa Maju Bersama dalam melakukan kegiatan distribusi produk paint otomotif.
Sistem Informasi Pemesanan Tiket Travel Berbasis Web (Studi Kasus: Lantra Wisata Travel PO. Sejahtera)
Authors: Nopianti Yurika , Ruliansyah Ruliansyah , Fadilah Evi
Published: August 2019

Kebutuhan sistem transportasi yang tinggi, dijadikan oleh banyak orang sebagai salah satu peluang usaha yang menguntungkan. Untuk itu mereka membuat suatu usaha untuk mempermudah masyarakat dalam melakukan mobilitas, dengan cepat dan mudah. Untuk kegiatan pemesanan tiket lantra wisata travel saat ini dilakukan secara konvensional, yaitu customer harus datang ke outlet perwakilan secara langsung sehingga memakan waktu yang cukup lama. Petugas operator travel sering mengalami kesulitan dalam melakukan pencarian data customer, mengupdate data customer, kesalahan dalam hal pemberian nomor kursi atau pencatatan jam keberangkatan yang diinginkan oleh calon customer. Hal ini sering menyebabkan ketidak akuratan data akibat kurang cermat sehingga menghambat kinerja karyawan dalam melaksanakan tugasnya. Penelitian ini membangun sistem informasi yang dapat membantu otomatisasi proses pemesanan tiket. Sistem informasi yang dibuat berbasis web dengan menggunakan metode waterfall. Sistem yang dibangun dapat membantu pihak travel dalam mengelola data pemesanan tiket sehingga mempermudah customer dalam proses pemesanan tiket dan operator dalam pengelolaan data travel.
En Uygun Güzergâh Algoritması ile Doğa Yürüyüşü Rotalarının Modellenmesi
Authors: Selim Serdar
Published: August 2019

Türkiye’nin
en önemli turizm destinasyonlarının başında gelen Antalya ili, alternatif
turizm olanakları kapsamında oldukça zengindir. Topoğrafik yapısı, iklimi,
bitki örtüsü, yaban hayatı varlığı, jeolojik ve jeomorfolojik özellikleri,
bölgeyi alternatif turizm açısından çeşitlendirmekte ve turistlerin ilgisini
çekmektedir. Dolayısıyla bölgedeki alternatif turizm faaliyetlerinin
belirlenmesi, haritalandırılması ve planlanması önem taşımaktadır. Bu
çalışmada, Türkiye’nin en önemli milli parklarından biri olan ve Termessos
Antik Kenti’ne ev sahipliği yapan Güllük Dağı Milli Parkı’nın, doğa yürüyüşüne
uygun yollarının CBS ile modellenmesi amaçlanmıştır. Doğal ve kültürel
değerlerin yerinde gösterilmesini amaçlayan ve aynı zamanda bir spor faaliyeti
olan doğa yürüyüşleri, bölgedeki doğal yapıyı bozmayan önemli bir alternatif
turizm faaliyetidir. Çalışma, Güllük Dağı Milli Parkı ve bu park içinde bulunan
Termessos Antik Kenti’nin doğa yürüyüşleri kapsamında ulaşılabilirliğine
odaklanmaktadır. Klasik turizm rotalarının oluşturulmasına alternatif olarak,
hızlı ve doğru sonuçlar üreten CBS teknolojileri ile en uygun yürüyüş
yollarının belirlenmesi ve haritalandırılması bu çalışmanın hedefidir. Bu
kapsamda bölgenin sayısal görüntüleri üretilmiş ve bu görüntüler en uygun
güzergâh (Least Cost Path) analizine tabi tutulmuştur. Bölgedeki eğim faktörü
dikkate alınarak yürüyüş için uygun eğime sahip alanlar belirlenmiş, başlangıç
ve bitiş noktaları arasında yürüyüş yolları oluşturulmuştur. Sonuç olarak,
Milli Parktaki Termessos Antik Kenti’ne, mevcut yürüyüş güzergâhı dışında
alternatif güzergâhlar belirlenmiş ve haritalandırılmıştır. Bu çalışma ile
doğal yapıya zarar vermeden bölgenin tanıtılması, uygun yürüyüş güzergâhların
oluşturulması, alternatif turizmin desteklenmesi hedeflenmiş, bölgeye yönelik
yapılacak planlamalarda kullanılabilecek bir model önerisi geliştirilmiştir.
Urgensi Pengelolaan Sumber Daya Manusia dalam Bisnis di Era Kontemporer
Authors: Suparwi S.
Published: August 2019

In today's globalization era companies be demanded must be able to compete with competitors who certainly not only sourced from domestic but also have to compete with competitors from abroad. The increasingly tight competition is what makes the business people must have quality human resources so that it has a good production process so that the productivity of the company can be realized. Human resources are key in every organization whether in the realm of education, politics, social, more so the business environment. although not as spaciously ancient time for its role in doing business activities but the role of human resources is quite significant and sometimes can't replaced in certain domain. Therefore, human resources as should be properly managed to function so always be productive and generate more profit for the company. Trend of human resource management in the contemporary era provides a new paradigm using information technology, so it’s very helpful in managing human resources.
Clinical performance evaluation of the Idylla™ EGFR mutation test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer
Authors: Delgado-Garcia Mercedes , Weynand Birgit , Izquierdo Lourdes Gómez , Barrera María José Hernández , Lobo Ángela María Blanco , Rodríguez Mar Varela , Guiu Xavier Matias , Nadal Ernest , Lobo Bélgica Márquez , Alarcão Ana , Casado Enrique de Álava , Biscuola Michele
Published: August 2019

BackgroundDetection of epidermal growth factor receptor ( EGFR) mutations in exons 18-21 is recommended in all patients with advanced Non-small-cell lung carcinoma due to the demonstrated efficiency of the standard therapy tyrosine kinase inhibitors in EGFR -mutated patients. Therefore, choosing a suitable technique for testing EGFR mutational status is crucial to warrant a valid result in a short turnaround time using the lowest possible amount of tissue material. The Idylla™ EGFR Mutation Test is a simple, fast and reliable method designed for the detection of EGFR mutations from formalin-fixed paraffin-embedded sample. The aim of this study was the evaluation of the Idylla™ EGFR Mutation Test on the Idylla™ System conducting a Clinical Performance Evaluation.MethodsEGFR mutational status was determined on 132 archived formalin-fixed paraffin-embedded tissue sections with Idylla™ technology. Results were compared with the results previously obtained by routine method in the reference lab (Therascreen ® EGFR RGQ PCR v2, Qiagen in Molecular Pathology lab, Hospital Universitario Virgen del Rocío de Sevilla)ResultsThe overall agreement between results obtained with the Idylla™ EGFR Mutation Test and the Comparator test method was 95.38% (with 1-sided 95% lower limit of 91.7%) showing Positive Diagnostic Agreement of 93.22% and Negative Diagnostic Agreement of 97.18%, with a Limit Of Detection ≤5%.ConclusionsThe Idylla™ EGFR Mutation Test passed its clinical validity performance characteristics for accuracy.
CD8-positive memory T cells in tumor-draining lymph nodes of patients with breast cancer
Authors: Vahidi Yasmin , Bagheri Mandana , Ghaderi Abbas , Faghih Zahra
Published: August 2019

Background

Human immunological memory is a hallmark of the adaptive immune system and plays an important role in the development of effective immune responses against tumors. In the present study, we aimed to determine the frequencies of CD8 + memory T cell subsets including stem memory T cells (TSCM) in tumor-draining lymph nodes of patients with breast cancer (BC).Methods

Mononuclear cells were obtained from axillary lymph nodes of 52 untreated patients with BC and stained for CD8, CCR7, CD45RO, CD95 markers to detect different subtypes of memory cells in the CD8 + lymphocyte population. Data were acquired with four-color flow cytometry and analyzed with CellQuest Pro software.Results

We observed that 47.65±2.66 of CD8+ lymphocytes expressed the CD45RO marker for memory T cells. Statistical analysis showed that the total frequency of central memory T cells (TCM) and their subset with low CD45RO expression was significantly higher in tumor-involved nodes compared to tumor-free ones (P=0.024 and P=0.017, respectively). Mean CD96 expression (based on mean fluorescence intensity) on the surface of TCM, their CD45RO hi TCM and CD45RO low subsets, and TSCM was higher in patients with stage II compared to those with stage I disease (P<0.05). The percentage of naive CD8 + T cells was significantly higher in tumor-involved lymph nodes compared to tumor-free ones (P=0.025).Conclusions

Our data collectively indicate no significant differences in the frequencies of CD8 + lymphocytes or their memory T cell subsets in tumor-draining lymph nodes of patients with BC. However, the frequency of CD45 low TCM along with naive CD8 + lymphocytes was higher in tumor-involved nodes, which suggests that after long-term exposure to the antigen, and despite the immune reaction in order to provide a pool of effective memory cells, memory cell differentiation is blocked in early-stage (CD45RO low ) due to tumor-derived suppressive factors. Identifying the molecular and cellular mechanisms behind this suppression can provide invaluable tools for adoptive T cell therapies in cancer.
Expression of heparanase regulates cell proliferation, apoptosis, migration and invasion in vitro in papillary thyroid carcinoma cells with multiple signaling pathways involved
Authors: Yang Chuanjia , Zhang Siyang , Chang Xiaoying , Huang Yonglian , Cui Dongxu , Liu Zhen
Published: August 2019

Background

Heparanase (HPSE) is an endo-β-D-glucuronidase, which is found overexpressed in various human cancers. The purpose of our work was to investigate the possible role of HPSE and the involved signaling molecules in the development of papillary thyroid carcinoma.

Methods

In this study, the expression plasmid of HPSE and RNA interference with shRNA specific for HPSE were used to elucidate the effects of HPSE on proliferation, apoptosis, migration and invasion in papillary thyroid carcinoma cells of B-CPAP. The probable downstream signaling molecules of HPSE were also explored.

Results

The results showed that upregulation of HPSE significantly promoted cell proliferation, migration and invasion of B-CPAP cells, and interfered with cell apoptosis. On the contrary, knockdown of HPSE exhibited the opposite effects. Compared with the parental cells, HPSE silencing cells showed attenuated capabilities of proliferation, migration and invasion, yet the apoptotic rate of transfected cells was increased. The activations of various signaling molecules correlated with cell biological behavior were found to be regulated by HPSE upregulation or knockdown.

Conclusions

Our results suggested that HPSE probably contributed to the progression and metastasis of papillary thyroid carcinoma, which were associated with multiple signaling pathways. HPSE could be a potent molecular target for the therapeutic strategy of papillary thyroid carcinoma.
Determinants of anemia among HIV positive children on Highly Active Antiretroviral Therapy (HAART) attending hospitals of North Wollo Zone, Amhara Region, Ethiopia, 2019: A case-control study
Authors: Abate Biruk Beletew , kassie Ayelign , Ahmed Mohammed
Published: August 2019

Introduction Anemia is one of the most commonly observed hematological abnormalities and an independent poor prognostic marker of HIV disease. The rate of progression and mortality in this subgroup of patients is high compared to non-anemic patients. WHO estimates that over 2 billion people are anemic worldwide and young children bear the world's highest prevalence rate of anemia. In Ethiopia, there is limited information about the determinant factors associated with anemia among HIV positive children. Objective The main purpose of this study was to assess the determinants of anemia among children on highly active anti-retroviral therapy attending hospitals of North Wollo Zone, Amhara Region, Ethiopia. Methods A case-control study was conducted on 350 HIV infected children on HAART attending Hospitals of North Wollo Zone, from February 1 to March 30, 2019. The study participants were selected with consecutive sampling technique. An adapted, interviewer-administered, and pre-tested questionnaire and chart review were employed to collect the data. Besides, blood and stool sample was investigated to determine hematologic indices and malaria and to investigate intestinal parasites respectively. Data were analyzed by using the SPSS version 24 statistical software and bivariate and multivariate logistic regression was used to identify predictors. Results A total of 350 HIV positive children (117 cases and 234 controls) were included in this study with an overall response rate of 100%.On multivariate analysis, variables which have spastically significance association with anemia were; had Amebiasis (AOR = 7.29, 1.22 - 43.56), had history of opportunistic infections (AOR = 9.63, 1.94 - 47.85), had malaria infection (malaria pf) (AOR = 4.37, 1.16 - 16.42),eating non-diversified (AOR = 10.39, 2.25 - 48.0), WGT –Age Z score value between -2_-3 (AOR = 9.80, 2.46 - 39.14),level of adherence (AOR = 2.31, 1.92, 7.77) and being from rural area(AOR = 8.8, 2.07 - 37.79). Conclusion In this study having parasitic infections, history of opportunistic infections, being malnourished, poor adherence to ART, caregivers living in the rural area and eating non-diversified foods were significantly associated with anemia among HIV positive children on HAART.
Association of sleep quality during pregnancy with stress and depression: a prospective birth cohort study in China
Authors: Gao Ming , Hu Jiajin , Yang Liu , Ding Ning , Wei Xiaotong , Li Lin , Liu Lei , Ma Yanan , Wen Deliang
Published: August 2019

Background: Sleep quality in the third trimester of pregnant women is related to mental health. However, There is still a lack of large-scale cohort research in the second trimester to confirms this relationship. We aim to assess the associations of sleep quality during the second trimester with antenatal stress and antenatal and postnatal depression.
Methods: We examined 1152 pregnant women from a prospective cohort study in China to assess the associations of sleep quality in the second trimester with antenatal stress, antenatal depression, and postnatal depression. We used linear regression models and logistic regression models to examine the associations of sleep quality (Pittsburgh Sleep Quality Index [PSQI]) during pregnancy with perinatal stress (Pregnancy Pressure Scale [PPS]) and depression (Edinburgh Postnatal Depression Scale [EPDS]) status. We further assessed the relationship in groups divided according to age.
Results: PSQI scores were positively associated with antenatal PPS scores (β: 1.52, 95% confidence interval [CI]: 1.28, 1.76), antenatal EPDS scores (β: 0.68, 95% CI: 0.58, 0.78), and postpartum EPDS scores (β: 0.51, 95% CI: 0.38, 0.64). Poor sleep quality was associated with antenatal stress status (odds ratio [OR]: 2.60, 95% CI: 1.79, 3.77), antenatal depression status (OR: 3.42, 95% CI: 2.48, 4.72), and postpartum depression status (OR: 2.40, 95% CI: 1.58, 3.64). The association of sleep quality in the second trimester with depression status was found in women older than 30 years old (OR: 4.12, 95% CI: 2.18, 7.78) and not in women younger than 30 years old.
Conclusion: Poor sleep quality in the second trimester among Chinese pregnant women is associated with stress and depression symptoms. Strategies to boost sleep quality should be considered during prenatal health care to improve women’s mental health status.
Exploring student awareness on critical factors which shape community engagement in the health science disciplines at a South African higher education institution
Authors: Bheekie Angeni , Huyssteen Mea van , Julie Hester
Published: August 2019

Background Community Engagement (CE) is cornerstone to South Africa’s higher education transformative agenda. Teaching disciplines across faculties have adopted varied CE implementation strategies, due to different theoretical interpretations. Undergraduate health science students are traditionally exposed to CE experiential learning programs, preparing them for professional practice. This study investigated final year students’ awareness of the critical factors which shape CE in the health science disciplines at a South African university.Method An exploratory descriptive qualitative study was conducted at an engaged university located in the Western Cape. Five discipline- specific focus group discussions were conducted with twenty seven final year students, purposively selected from five health sciences faculties, using an adaption of Furco’s self-assessment rubric. Thematic analysis was conducted on the transcribed data to identify the factors deemed critical for CE using Furco’s self-assessment tool as the coding framework. Trustworthiness of the data and findings were ensured. Ethics approval was obtained indicating that the research satisfied the ethics principles related to informed consent, respect for the participants ‘rights in terms of privacy, autonomy, beneficence and confidentiality.Results The a priori t hemes identified were the university’s philosophy and mission related to CE, student involvement, faculty involvement, community participation and partnerships and institutional support for CE. The cross-cutting themes that emerged across these critical factors of Furco’ included: siloism in the university, interprofessional education and monitoring and evaluation for impact. These health science students indicated that CE awareness was limited to discipline-based programs, indicative of a siloed approach. In addition, varied theoretical interpretations of CE emerged. Interprofessional education was lacking across the disciplines, even though it underpins professional practice. Participants reiterated that a central CE unit is required to co-ordinate and evaluate CE programs. Occupational therapy participants, however, reflected a critical consciousness that is congruent with an assets-based approach to CE.Conclusion The University of the Western Cape should facilitate stewardship in implementing Boyer’s 'scholarship of engagement' to ensure consistency in CE approach in the health science curriculum. Such an approach would deepen students understanding and application of CE.
Validation of the French translation of the Dutch Residency Educational Climate Test
Authors: Majbar Anass Mohammed , Majbar Yassin , Benkabbou Amine , Amrani Laila , Bougtab Abdeslam , Mohsine Raouf , Souadka Amine
Published: August 2019

BackgroundThe learning environment is one of the most influential factors in training of medical residents. The Dutch Residency Educational Climate Test (DRECT) is one of the strongest instruments for measuring the learning environment. However, it has not been translated in French. The objective of this study is the psychometric validation of the DRECT French version. MethodsAfter translation of the DRECT questionnaire into French, residents of five Moroccan hospitals were invited to complete the questionnaire between July and September 2018. Internal consistency, temporal stability and confirmatory factor analysis were used to analyze psychometric properties of the translated version. ResultsDuring the study period, 211 residents completed the questionnaire. The French version had a good internal consistency (Cronbach alpha score = 0.95) and a good temporal stability (correlation score between two measurements = 0.89). Confirmatory factor analysis showed an adequate model fit with the following indicators: SRMR = 0.058 / RMSEA = 0.07 / CFI = 0.88 / TLI = 0.87. ConclusionThis study enabled the psychometric validation of DRECT French translation. It could be used to evaluate the residency learning environment in francophone countries.
General practitioners’ views on use of patient reported outcome measures in primary care: a cross-sectional survey and qualitative study
Authors: Turner Grace M , Litchfield Ian , Finnikin Sam , Aiyegbusi Olalekan Lee , Calvert Melanie
Published: August 2019

Background

Patient reported outcome measures (PROMs) are increasingly used to assess impact of disease and treatment on quality of life and symptoms; however, their use in primary care is fragmented.

We aimed to understand the current use of PROMs in primary care, barriers and facilitators, and how their use might be optimised.

Methods

Cross-sectional survey and semi-structured interviews among general practitioners (GPs) in England. GPs’ opinions were explored using an electronic, self-completed questionnaire disseminated to 100 GPs via an online doctors’ community and semi-structured qualitative interviews with 25 GPs.

Results

Most GPs surveyed (77/100; 77%) reported using one or more PROM, primarily to aid clinical management (n=66) or as screening/diagnostic tools (n=62).

Qualitative interviews highlighted challenges in identifying and selecting PROMs; however, some GPs valued PROMs for shared decision making and to direct patient discussions. The interviews identified key barriers to PROM use including: time constraints; insufficient knowledge; lack of integration into clinical systems; and PROMs being mandated without consultation or explanation. Evidence of the benefit of PROMs is required to promote uptake and use of PROMs in primary care.

Conclusion

Implementation of PROMs in primary care requires integration with clinical systems, a bottom-up approach to PROM selection and system design involving meaningful consultation with patients and primary care clinicians and training/support for use.
A Pilot Evaluation of a Rapid Screening Test for Nosocomial Meningitis or Pneumonia at a Neurosurgical Intensive Care Unit in Sweden
Authors: Ramezani Amir , Darbani Roya , Eng Lars , Lönn Johanna , yin lan , Theodorsson Annette , Nayeri Fariba
Published: August 2019

Background

When post-neurosurgery patients develop fever, there are no convenient methods to immediately indicate the site of infection. The choice of empirical antibiotic therapy is evidently different in nosocomial meningitis compared to ventilator-associated pneumonia or urinary tract infection. Conventional bacterial cultures have a risk of being false negative due to antibiotic prophylaxis, and direct microscopic analysis of cerebrospinal fluid from such patients has limited diagnostic value. Due to the substantial mortality associated with nosocomial meningitis, broad spectrum antibiotics in high dosage are therefore commonly administered. Neutrophils as innate immunity system, trap and kill bacteria by neutrophil extracellular traps (NETs). NETs is composed of extracellular DNA and is released in cerebrospinal fluid during bacterial meningitis. Using a combination of sulphated-glycosaminoglycan and aniline dyes a platform was developed that reacted to extracellular host DNA and changed color within one minute in proportion to the amount of NETs in body fluid. This present study aimed to evaluate the sensitivity and specificity of the index strip test in identifying the site of infection.

Methods

Between November 2015 and November 2017, cerebrospinal fluid, bronchoalveolar fluid, and urine were collected on Mondays and Thursdays from the patients during the course of management (199 samples from 117 cases). The rapid strip test (1 minute) was used for simultaneous analysis of the fresh samples. The final diagnosis was settled at discharge.

Results

A total of 75 patients (64%) had received empirical antibiotic therapy against nosocomial meningitis, while only 19 patients (16%) had a verified diagnosis. The strip test could distinguish a verified meningitis (n=19) with 89.5% sensitivity and 92.5% specificity. The test also identified ventilator-associated pneumonia (n=32) with 93.8% sensitivity and 86.8% specificity.

Conclusions

The rapid strip test analyzed cerebrospinal and bronchoalveolar fluid from febrile patients post-neurosurgery and indicated the site of infection with clinically relevant sensitivity and specificity, indicating its potential to minimize the unnecessary use of antibiotics.
Preparation of novel Ti-based MnOx electrodes by spraying method for electrochemical oxidation of Acid Red B
Authors: Xu Xuelu , Zhao Jiao , Bai Subei , Mo Rongrong , Yang Yan , Liu Weifeng , Tang Xiaojia , Yu Hang , Zhu Yimin
Published: August 2019

At different calcination conditions, titanium-based manganese oxides (MnOx) electrodes were fabricated by spraying method without adhesive. The MnOx/Ti electrodes were applied in electrochemical oxidation of wastewater treatment for the first time. The surface morphologies of electrodes were tested by scanning electron microscopy. The formation of different manganese oxidation states on electrodes was confirmed by X-ray diffraction and X-ray photoelectron spectroscopy. The electrochemical properties of the electrodes have been performed by means of cyclic voltammetry and electrochemical impedance spectroscopy. The characterizations revealed that the MnOx/Ti-350(20) electrode, prepared at calcination temperature of 350 °C for 20 min, exhibited fewer cracks on the electrode surface, larger electrochemically effective surface area and lower charge transfer resistance than electrodes prepared at other calcination conditions. Moreover, Acid Red B was used as target pollutant to test the electrode activity via monitoring the concentration changes by UV spectrophotometer. The results showed that the MnOx/Ti-350(20) electrode presented the best performance on decolorization of Acid Red B with the lowest cell potential during the process of electrochemical oxidation, and the chemical oxygen demand (COD) conversion was 50.7%. Furthermore, the changes of Acid Red B during the electrochemical oxidation process were proposed by the UV–vis spectra.
EURODAC AS AN INSTRUMENT OF THE EU RETURN POLICY
Authors: Strąk Katarzyna
Published: August 2019

The proposed recast Eurodac Regulation of 2016 extends its previous scope so that both illegally residing third-country nationals and those who have entered the EU irregularly at its external borders could be identified and so that this information could be used by Member States to re-document them for return purposes. In this way Eurodac will, according to the European Commission, contribute to the fight against irregular migration. The proposal is meant to improve the effectiveness of the EU return policy by facilitating the identification of persons illegally on the territory of the EU. After it is adopted, the new Eurodac Regulation may be considered as an example of a flanking instrument of the EU return policy. It should be emphasised that on the one hand the provisions foreseen in the Regulation are highly valuable when it comes to ensuring the effectiveness of the EU return policy. On the other hand, however, it is still unknown what effects it will bring when adopted.
Capacidade funcional submáxima e variabilidade hemodinâmica em indivíduos com diabetes mellitus tipo 2
Authors: Mohr Fernanda , Beber Gabrieli Costa , Winkelmann Eliane Roseli
Published: August 2019

Diabetes Mellitus; Aptidão física; Saúde Pública.
Acessibilidade geográfica e econômica na Estratégia Saúde da Família: avaliação da satisfação por usuários com hipertensão arterial sistêmica
Authors: Melo Erik Cristóvão Araújo de , Figueiredo Tânia Maria Ribeiro Monteiro de , Cardoso Maria Aparecida Alves , Paes Neir Antunes
Published: August 2019

Acesso aos serviços de saúde; Hipertensão; Avaliação de serviçosde saúde; Saúde da família.
Características de sono e atividade física entre adolescentes do município de São Carlos (SP)
Authors: Piazzetta Eliza , Del Ciampo Luiz Antonio , Zeppone Silvio Cesar
Published: August 2019

Sono; Adolescente; Atividade motora.
Estudo do perfil dos pacientes portadores de Síndromes Falciformes acompanhados no Serviço de Hematologia do Centro Estadual de Hemoterapia e Hematologia do Espírito Santo (HEMOES)
Authors: Furtado Alexandre Neves , Motta Jovarci , Santos Marcos Daniel de Deus
Published: August 2019

Anemia; Anemia Falciforme; Traço Falciforme.
Care and prevention of diabetic foot: perceptions of diabetic patients
Authors: Salgueiro Andréia Caroline Fernandes , Silva Elane Fabíola de Sousa Jerônimo da , Brito Verônica Bidinotto , Puntel Gustavo Orione , Folmer Vanderlei
Published: August 2019

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Fatores que interferem na qualidade das amostras e dos procedimentos de coleta de escarro em sintomáticos respiratórios
Authors: Guidoni Leticia Molino , Brioschi Ana Paula , Zandonade Eliana , Palaci Moises , Hadad Davi Jamil Hadad Jamil , Sanchez Mauro Niskier , Maciel Ethel Leonor Noia
Published: August 2019

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Prevalência de varizes em trabalhadores mantidos em posição ortostática
Authors: Ferraz Renato Ribeiro Nogueira , Macedo Rosiane Souza , Fornari João Victor , Barnabé Anderson Sena
Published: August 2019

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nternações por condições sensíveis a atenção primária em município da região Norte do Espírito Santo
Authors: Luciano Thaís Verly , Dias Jerusa Araújo
Published: August 2019

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Utilização de medicamentos antieméticos em oncologia pediátrica: riscos e benefícios
Authors: Santos Sandna Larissa Freitas dos , Barros Karla Bruna Nogueira Torres , Prado Regilane Matos da Silva
Published: August 2019

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As plantas medicinais da Relação Nacional de Plantas Medicinais de Interesse ao Sistema Único de Saúde (RENISUS) com potencial antifúngico
Authors: Marmitt Diorge Jônatas , Rempel Claudete , Goettert Márcia Inês , Silva Amanda do Couto e
Published: August 2019

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A utilização de plantas medicinais e da fitoterapia em comunidades assistidas pela Estratégia Saúde da Família
Authors: Araújo Manuela Souza Correia de , Costa Josefa Waldenora da , Costa Ana Alessandra da , Tocchio Pollyana Steffany Paiva de Lima , Araújo Laianne Shirley de Azevedo , Nunes Vilani Medeiros de Araújo
Published: August 2019

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Avaliação de Projetos em Saúde na Fundação de Amparo à Pesquisa e Inovação do Espírito Santo (FAPES)
Authors: Bueno George Nunes , Farias Cynthia Moura Louzada , Sampaio Poliane Barbosa , Siqueira Marluce Mechelli de
Published: August 2019

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Organizações Sociais de Saúde nos hospitais públicos do Estado do Espírito Santo
Authors: Turino Fabiana , Soares Gabriella Barreto , Mansur Marília Coser , Sodré Francis
Published: August 2019

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Condutas de saúde de universitários ingressantes e concluintes de cursos da área da saúde
Authors: Luciane Campos Luciane , Isensse Daniela Cristine , Rucker Tanise Cumiotto , Bottan Elisabete Rabaldo
Published: August 2019

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Conhecimento da gestante sobre o HIV e a transmissão vertical em São José do Rio Preto, São Paulo, Brasil
Authors: Jordão Bruna Amato , Espolador Gabriela Martins , Finochio Sabino Ana Maria Neves , Tavares Beatriz Barco
Published: August 2019

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Perfil epidemiológico de pacientes internados por doença falciforme no estado do Espírito Santo, Brasil (2001-2010)
Authors: Sabino Mayara Ferreira
Published: August 2019

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Descrição das internações por aborto no estado do Espírito Santo, Brasil
Authors: Batista Renata Queiroz , Koch Daniely Fontoura , Bispo Aline Marcia de Souza , Luciano Thaís Verly , Velten Ana Paula Costa
Published: August 2019

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Dificuldades enfrentadas pelos profissionais na utilização da caderneta de saúde da criança
Authors: Silva Fabiane Blanco e , Gaíva Maria Aparecida Munhoz
Published: August 2019

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A dispensação como oportunidade para a identificação e prevenção de problemas relacionados a medicamentos
Authors: Cardoso Thaissa Costa , Ferreira Tatyana Xavier Almeida Matteucci , Prudente Luciana Resende , Lopes Flávio Marques , Dewulf Nathalie de Loudes Souza
Published: August 2019

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Inserção da biotecnologia e temas da área da saúde na mídia brasileira
Authors: Grein Taiana Aparecida Duarte , Nascimento Vagner Ferreira do , Hattori Thalise Yuri , Lemes Alisséia Guimarães , Terças Ana Claúdia Pereira , Silva Rulio Glécias Marçal da , Baggio Érica , Silva Ledinéia Benedito
Published: August 2019

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Análise das possíveis interações fármaco-alimento/nutriente em uma instituição asilar no sul de Minas Gerais
Authors: Carlos Giane Bueno , Francisco Larissa Nogueira , De Moraes Thays Corrêa , Cerdeira Cláudio Daniel , Santos Gersika Bitencourt
Published: August 2019

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O uso de medidas autorrelatadas é válido para a avaliação do estado nutricional da população em geral?
Authors: Ferriani Lara Onofre , Viana Maria Carmen
Published: August 2019

Is the use of self-reported measures valid for the evaluation of the nutritional status of the general population?
Le Fort II osteotomy for medium-face fracture sequel correction
Authors: Verbicaro Thalyta , Sebastiani Aline Monise , Gerber Jennifer Tsi , Fernandes Bruno Viezzer , Zielak João Cesar , Scariot Rafaela , Klüppel Leandro Eduardo
Published: August 2019

Introduction: Fractures should be treated by a multi-professional team to minimize sequels. The surgery aims to establish a good maxillary, mandibular relationship to improve mastication and phonetics and may benefit esthetics. Objective: to report the surgical procedure with Le Fort II osteotomy for correction of class III dentofacial deformity and the nasomaxillary deficiency caused by trauma. Case report: Patient victim of aggression for 10 years suffered a Le Fort II fracture. The fracture was not treated and the patient developed a severe anteroposterior defect of the nasomaxillary complex andClass III occlusion. The surgery for correcting deformities was performed with the bicoronal, lower eyelid and intraoral accesses. Le Fort II pyramidal osteotomy was performed with a piezoelectric motor to advance 7 mm the nasomaxillary complex. Conclusion: Le Fort II osteotomy is considered satisfactory for advancing the nasomaxillary complex, improving the patient´s psychosocial function and development.
Reposicionamento horizontal mandibular com próteses provisórias removíveis tipo overlay – relato de caso Mandibular horizontal repositioning with removable temporary overlay prostheses – case report
Authors: Stroparo Jeferson Luis de Oliveira , Rodrigues Fabrício Guimarães , Leão Moira Pedroso , Dziedzic Dilcele Silva Moreira , Zielak João César
Published: August 2019

Introduction: Rehabilitation with the use of overlay-type removable prostheses is indicated in cases of more severe occlusal dysfunction. This type of treatment meets the need for more immediate results, providing aesthetic improvement while the rehabilitation work is being done, while promoting the gradual rehabilitation of occlusal function, re-adjusting the intermaxillary relationship. In addition, the patient can anticipate the final result of the treatment beforethe definitive prosthesis is made. Objective: To show a clinical case of planning and execution of removable overlays. Case report: JCF patient had occlusal dysfunction and presented as main complaint the aesthetic and functional deficiency. He used a removable partial denture (PPR) only on the upper arch. The existing prosthesis did not present stability due to the loss of some dental elements, pillars of the PPR. Two overlays (upper and lower) were indicated because the patient had good periodontal conditions in the remaining dentalelements that were in a favorable position. Necessary exodontia, adequacy of the buccal environment with sub and supragingival scaling and the fabrication of overlays were performed. Conclusion: The use of temporary overlays can provide the necessary time for the patient to adapt to the new occlusal conformation in the period in which the restorations and definitive prostheses are expected to be performed. The use of overlays presented a satisfactoryresult for the proposed treatment, since it promoted the functional rehabilitation, restored aesthetic, even temporarily, and motivated the patient to continue the treatment. According to the patient, there were significant improvements in chewing quality and self-esteem.