bluuebunny/crossref_metadata_2025 huggingface dataset:
The hepatic lipidome and HNF4α and SHBG expression in human liver
Authors: Winters Stephen J , Scoggins Charles R , Appiah Duke , Ghooray Dushan T
Published: September 2020

Low plasma levels of sex hormone-binding globulin (SHBG) are a marker for obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. The transcription factor HNF4α is a major determinant of hepatic SHBG expression and thereby serum SHBG levels, and mediates in part the association of low SHBG with hyperinsulinemia and hepatic steatosis. We analyzed the lipidome in human liver specimens from a cohort of patients who underwent hepatic resection as a treatment for cancer, providing insight into hepatic lipids in those without extreme obesity or the clinical diagnosis of NAFLD or non-alcoholic steatohepatitis. Both steatosis and high HOMA-IR were associated with higher levels of saturated and unsaturated FA, other than arachidonic, with the most dramatic rise in 18:1 oleate, consistent with increased stearoyl-CoA desaturase activity. Individuals with low HOMA-IR had low levels of total hepatic fatty acids, while both low and high fatty acid levels characterized the high HOMA-IR group. Both insulin resistance and high levels of hepatic fat were associated with low expression levels of HNF4α and thereby SHBG, but the expression of these genes was also low in the absence of these determinants, implying additional regulatory mechanisms that remain to be determined. The relationship of all FA studied to HNFα and SHBG mRNAs was inverse, and similar to that for total triglyceride concentrations, irrespective of chain length and saturation vs unsaturation.
PRKACB variants in skeletal disease or adrenocortical hyperplasia: effects on protein kinase A
Authors: Espiard Stephanie , Drougat Ludivine , Settas Nikolaos , Haydar Sara , Bathon Kerstin , London Edra , Levy Isaac , Faucz Fabio R , Calebiro Davide , Bertherat Jérôme , Li Dong , Levine Michael A , Stratakis Constantine A
Published: September 2020

Genetic variants in components of the protein kinase A (PKA) enzyme have been associated with various defects and neoplasms in the context of Carney complex (CNC) and in isolated cases, such as in primary pigmented nodular adrenocortical disease (PPNAD), cortisol-producing adrenal adenomas (CPAs), and various cancers. PRKAR1A mutations have been found in subjects with impaired cAMP-dependent signaling and skeletal defects; bone tumors also develop in both humans and mice with PKA abnormalities. We studied the PRKACB gene in 148 subjects with PPNAD and related disorders, who did not have other PKA-related defects and identified two subjects with possibly pathogenic PRKACB gene variants and unusual bone and endocrine phenotypes. The first presented with bone and other abnormalities and carried a de novo c.858_860GAA (p.K286del) variant. The second subject carried the c.899C>T (p.T300M or p.T347M in another isoform) variant and had a PPNAD-like phenotype. Both variants are highly conserved in the PRKACB gene. In functional studies, the p.K286del variant affected PRKACB protein stability and led to increased PKA signaling. The p.T300M variant did not affect protein stability or response to cAMP and its pathogenicity remains uncertain. We conclude that PRKACB germline variants are uncommon but may be associated with phenotypes that resemble those of other PKA-related defects. However, detailed investigation of each variant is needed as PRKACB appears to be only rarely affected in these conditions, and variants such as p.T300M maybe proven to be clinically insignificant, whereas others (such as p.K286del) are clearly pathogenic and may be responsible for a novel syndrome, associated with endocrine and skeletal abnormalities.
Comunicación política desde el ático
Authors: Toapanta Alex
Published: September 2020

A través del análisis del discurso ideológico aplicado a los 12 enlaces digitales realizados por el expresidente de Ecuador, Rafael Correa, entre el 12 de agosto de 2017 y el 15 de junio de 2019, en el presente trabajo académico nos hemos trazado como objetivo conocer los elementos que componen la estructura discursiva y la comunicación política empleada para cuestionar el proceder de los dos años de Gobierno de quien fuera su sucesor, Lenín Moreno.
En total son 1 269 minutos de grabación alojadas en el portal web YouTube, los cuales encierran una serie de prácticas políticas que resultan interesantes conocer y analizar: simplificación y despersonalización del mensaje, deslegitimización política, construcción de símbolos y configuración de imagen, entre otros mecanismos que consideramos, también, constituyen el germen de lo que podría ser su participación en las elecciones presidenciales del 2021.
Origins and Evolutionary Patterns of the1.688Satellite DNA Family inDrosophilaPhylogeny
Authors: de Lima Leonardo G , Hanlon Stacey L , Gerton Jennifer L
Published: September 2020

Satellite DNAs (satDNAs) are a ubiquitous feature of eukaryotic genomes and are usually the major components of constitutive heterochromatin. The 1.688 satDNA, also known as the 359 bp satellite, is one of the most abundant repetitive sequences in Drosophila melanogaster and has been linked to several different biological functions. We investigated the presence and evolution of the 1.688 satDNA in 16 Drosophila genomes. We find that the 1.688 satDNA family is much more ancient than previously appreciated, being shared among part of the melanogaster group that diverged from a common ancestor ∼27 Mya. We found that the 1.688 satDNA family has two major subfamilies spread throughout Drosophila phylogeny (∼360 bp and ∼190 bp). Phylogenetic analysis of ∼10,000 repeats extracted from 14 of the species revealed that the 1.688 satDNA family is present within heterochromatin and euchromatin. A high number of euchromatic repeats are gene proximal, suggesting the potential for local gene regulation. Notably, heterochromatic copies display concerted evolution and a species-specific pattern, whereas euchromatic repeats display a more typical evolutionary pattern, suggesting that chromatin domains may influence the evolution of these sequences. Overall, our data indicate the 1.688 satDNA as the most perduring satDNA family described in Drosophila phylogeny to date. Our study provides a strong foundation for future work on the functional roles of 1.688 satDNA across many Drosophila species.
Medienkompetenz
Authors: Kreutzer Ralf T.
Published: September 2020

Heute bedarf es aufgrund der hohen Mediendichte mehr denn je des Aufbaus von Medienkompetenz. Diese beschreibt die Fähigkeit, sowohl die verschiedenen Medienkanäle als auch deren Inhalte kompetent und vor allem kritisch zu nutzen sowie mit und in diesen zu agieren.
BioResources - An online scientific journal devoted to lignocellulosic materials for new end uses and new capabilities
Authors: Hubbe M. A. , Lucia Lucian A.
Published: September 2020

In this inaugural issue, the Co-Editors of BioResources would like to welcome you. In your role as a reader, we welcome you to download scholarly articles and opinion pieces; this is an open-access journal, providing a maximum of potential impact. BioResources will deal with new and emerging uses of materials from lignocellulosic sources, including wood and crop residues. Topics will include biofuels, biomass-derived chemical products, papermaking technology, and other new or improved uses of biomaterials. We also would like to welcome you as a prospective author. Our goal is to maintain very high standards of peer-review, as well as providing a mix of scholarly research articles, review articles, and editorials. By using an automated, online system of review and publication, we hope to accelerate scientific discourse. Our hope is to contribute to progress in the direction of a post-petroleum economy, taking advantage of the renewable, biodegradable, and relatively abundant nature of materials from lignocellulosic sources.
Enzymes improve ECF bleaching of pulp
Authors: Bajpai Pratima , Anand Aradhna , Sharma Nirmal , Mishra Shree P. , Bajpai Pramod K. , Lachenal Dominique
Published: September 2020

The delignification efficiency of different laccase enzymes was examined on the eucalyptus Kraft pulp. The laccase enzyme from Trametes versicolor showing the highest delignification efficiency was selected and used in the elemental chlorine-free bleaching sequence for improving the pulp bleachability. A n appreciable reduction in chlorine dioxide consumption was also obtained. Further reduction in chlorine dioxide consumption was obtained when the same laccase treated pulp was subjected to an acid treatment after the extraction stage followed by the DE P D sequence. Elemental-chlorine free bleaching was also performed using the xylanase-laccase treated pulp. Xylanase treatment was incorporated to the laccase mediator system in the elemental-chlorine free bleaching both sequentially and simultaneously. The bleaching sequence DE P D followed and in both the cases, the reduction in chlorine dioxide consumption was greater in comparison to the control. The chlorine dioxide consumption was reduced further when xylanase-laccase treated pulp was given an additional acid treatment. The final pulp properties of the treated pulps were comparable to the control pulp.
Papermaking fibers from giant reed (Arundo donax L.) by advanced ecologically friendly pulping and bleaching technologies
Authors: Shatalov Anatoly A. , Pereira Helena
Published: September 2020

The anatomical structure and chemical composition of the stem-wall material of giant reed is considered from the viewpoint of raw material characterization for industrial fiber production. The effect of stem morphology (nodes and internodes) on pulping results and general pulp properties is discussed. The advantages of application of modern organic solvent based (organosolv) pulping technologies to giant reed are shown in comparison with the conventional (kraft) method. The conditions optimization for Ethanol-Alkali pulping (a selected organosolv pulping process) is given, and the chemical kinetics of the principal macromolecular components during ethanol-alkali pulping is described. The bleachability of organosolv pulps by short totally chlorine free (TCF) bleaching sequences using hydrogen peroxide and ozone as the active bleaching chemicals without pulp pre-delignification is examined and compared with kraft pulps. The enzymatic pre-treatment of reed organosolv pulps by commercial xylanase preparation is considered as a possibility toward the improvement of pulp bleachability.
Decay resistance of cement-bonded oriented strand board
Authors: Papadopoulos Antonios N.
Published: September 2020

The objective of this study was to evaluate the decay resistance of cement bonded oriented strand board (OSB) against brown ( Coniophora puteana) and white rot ( Termites versicolor ) fungi. Overall, both fungi failed to attack the cement-bonded OSB. Boards made with 3.0 cement-to-wood ratio showed weight gain instead of weight loss. Therefore, it is recommended that cement-bonded OSB is technically suitable for exterior use where both moisture and favourable conditions for fungi development are present.
Evaluation of commercial cellulase preparations for the efficient hydrolysis of hydrothermally pretreated empty fruit bunches
Authors: Yang Jungwoo , Kim Ji Eun , Kim Jae Kyun , Lee Sung ho , Yu Ju-Hyun , Kim Kyoung Heon
Published: September 2020

The performance of cellulase in the enzymatic saccharification of lignocellulose depends on the characteristics of lignocellulosic biomass feedstocks and the pretreatment method used. Efficient hydrolysis of specifically pretreated lignocellulose necessitates the knowledge of the characteristics of the optimal commercial cellulases. In this study, commercial cellulase preparations (Accellerase™ 1000, Accellerase® 1500, and Spezyme® CP from DuPont and Cellic® CTec2 from Novozymes) were evaluated for their hydrolysis efficiency of hydrothermally pretreated empty fruit bunches (EFBs). The highest glucose yields of 91.3% and 84.7% were achieved for 30 FPU of Cellic® CTec2/g glucan with and without Cellic® HTec2, respectively. Of the four cellulases tested, Cellic® CTec2, which showed the highest cellobiohydrolase, xylanase, and β-glucosidase activities, showed the highest glucose yield in the enzymatic hydrolysis of hydrothermally pretreated EFBs. The results of this study are valuable for those who plan to enzymatically hydrolyze hydrothermally pretreated EFBs.
Trajectories of Lung Function in Infants and Children: Setting a Course for Lifelong Lung Health
Authors: Jordan Brian K. , McEvoy Cindy T.
Published: September 2020

For healthy individuals, it is increasingly accepted that lung function follows along an individual percentile established early in life and that the level of maximal function reached as a young adult can affect the subsequent development of lung disease that occurs with the normal aging process. This emphasizes the need to maximize early lung function. The trajectories of lung function are at least partially established by perinatal factors, including prematurity and in utero exposures (tobacco exposure, nutrition, inflammation, etc), although they can also be affected by a variety of additional factors and exposures throughout the life span. Whether lung function trajectories can be impacted or reset if established under suboptimal conditions is an unanswered question, offering new avenues for research. In this review, we will summarize important articles outlining lung function trajectories and linking pediatric lung function tests to adult lung function tests decades later. We will focus on perinatal factors and outline progress and opportunities for further investigation into the potential ability to reset trajectories to impact long-term lung health.
Biogenerated Polymers: An Enviromental Alternative
Authors: Salazar Sánchez Margarita Del Rosario , Cañas Montoya Jorge Arturo , Villada Castillo Hector Samuel , Solanilla Duque Jose Fernando , Rodríguez Herrera Raul , Avalos Belmotes Felipe
Published: September 2020

Biogenerated polymers are of great interest in industry in general, due to the trend of reduced use of petroleum-derived materials. However, their development costs are high and the benefit is still low. Currently, biodegradable alternatives are available from biogenerated polymers approximately 10% of the plastics market. Its consumption is estimated at 50,000 tons/year in Europe, with a share of less than 1%. In this order of ideas, the objective of this revision is to show the importance of the production of biogenerated polymers in the manufacture of biodegradable materials, from their formulation that contains macromolecules of natural origin such as oligomers or monomers. To this purpose, we will discuss topics related to several types of biogenerated polymers, such as chitosan, starch, polybutylene succyanate and polylactic acid, which have been used for the development of biogenerated polymeric materials by different research groups.
Analysis of aristolochlic acids and evaluation of antibacterial activity of
Aristolochia clematitis L.
Authors: Bartha Gergely Sámuel , Tóth Gergő , Horváth Péter , Kiss Eszter , Papp Nóra , Kerényi Monika
Published: September 2020

Introduction

Several Aristolochia species were used as medicinal
herb across Europe and in recent years, their antimicrobial activity has also been
investigated.

Materials and methods

In this study, A. clematitis was selected to evaluate
the aristolochic acids I and II (AA I and AA II) concentrations and the antimicrobial
activity of methanol, hexane, butanol, and ethyl acetate extracts of the root, stem,
leaf, root, and fruit. AA I and AA II contents were measured by a validated
high-performance liquid chromatography–ultraviolet method.

Results

Each fraction of the plant contained AA I and AA II and the root was found to
have the highest contents of AA I (1.09%) and AA II (0.7454%). The minimum inhibitory
concentrations of all extracts were determined by standard microdilution method. The
fruit’s extracts showed the most efficient antimicrobial effect against both
methicillin sensitive and resistant Staphylococcus aureus
strains.

Conclusion

Correlation between the AA I and AA II concentrations and the antimicrobial
effect was not found.
Fenntartó kezelési módok felnőttkori rosszindulatú hematológiai betegségekben
Authors: Udvardy Miklós
Published: September 2020

Absztrakt:

A fenntartó kezelésmódok elsősorban a gyermekkori akut lymphoid leukaemiában
voltak általánosak, felnőttkorban ritkábbak. Fokozatosan alakultak ki fenntartó
kezelési módok néhány felnőttkori hematológiai betegségben, például néhány
lymphomában – például follicularis lymphoma, köpenysejtes lymphoma –, s az
elmúlt években a myeloma fenntartó kezelése egyre jelentősebb teret nyert. Mára
egyre több onkohematológiai entitás fenntartó kezelése egyre erősödő tendencia,
sokszor a kezdetben csak az indukciós vagy relapsusos esetekben hatékonynak
bizonyuló kis molekulák előtérbe kerülése várható fenntartó készítményként is.
Myelomában a prognózisfüggő fenntartó kezelési mód, mely gyakran akár a
visszaesésig tart, mára minden nemzetközi és komolyabb ajánlás része. Az elmúlt
években megjelentek fenntartó kezelési módok a felnőttkori akut myeloid
leukaemiában is, teljesen új elemként akár transzplantációt követően, akár a
nélkül. Megváltozott az a szemlélet, hogy egy nehéz kemoterápia vagy éppen a
csontvelő-átültetés azért is jó, mert utána kezelésmentessé válhat a betegek
túlnyomó része. Fontos az is, hogy a fenntartó kezelés ne legyen megterhelő, ne
kelljen túl sok időt a kórházban tölteni, minél inkább egyszerű, akár tablettás
formájú lehessen. Vannak tendenciák arra, hogy az indukció, a konszolidáció és a
fenntartó kezelés (például a myeloma egyes esetei) egyre inkább kontinuumot
képezzenek. Orv Hetil. 2020; 161(38): 1623–1628.
First record of non-native platyfish, Xiphophorus maculatus (Günther, 1866) (Cyprinodontiformes, Poeciliidae), in the Jaguaribe River basin, northeastern Brazil
Authors: Ramos Telton Pedro Anselmo , Gomes Ponce de Carvalho Rocha Yuri , Costa Silvia Yasmin Lustosa , Barbosa José Etham de Lucena
Published: September 2020

We provide the first record of Xiphophorus maculatus (Günther, 1866) in a river basin in the northeastern Brazil. Specimens were collected in the Jaguaribe River basin, João Pessoa, Paraíba state, Brazil. Two hundred eighty-one specimens, corresponding to 143 males and 138 females of X. maculatus, were collected at nine sites along the basin, from 2017 to 2019. Specimens total length ranged from 17.5 to 26.6 mm in males and from 11.7 to 32.7 mm in females. Introduction of non-native species greatly threatens the biological diversity worldwide. When introduced into a new habitat, X. maculatus usually decreases microcrustacean, macroinvertebrate and native fish populations.
Pengaruh Jenis Pakan yang Berbeda Terhadap Jumlah Telur pada Ikan Beseng-Beseng (Marosatherina ladigesi Ahl, 1936)
Authors: Kariyanti Kariyanti , Savitri Andi Lawi Yeni
Published: September 2020

Domestikasi induk ikan beseng-beseng telah berhasil dilakukan. Upaya pengelolaan ini memerlukan dukungan informasi mengenai jenis pakan yang baik untuk tingkat kematangan gonad agar menghasilkan jumlah telur yang banyak sehingga bisa memproduksi benih. Penelitian ini bertujuan untuk mengkaji jumlah telur ikan beseng-beseng (Marosatherina ladigesi) yang dihasilkan dalam satu kali memijah dengan pemberian pakan berbeda yaitu Culex sp, Artemia sp. dan pellet. Penelitian ini dilakukan selama 5 bulan, mulai bulan April 2019 sampai Agustus 2019 dengan desain experimental rancangan acak lengkap. Pemijahan alami dilakukan dalam penelitian ini dengan pengamatan perbedaan sistem pemijahan (massal dan individual). Hasil penelitian menunjukkan induk ikan beseng-beseng yang diberi pakan Artemia sp menghasilkan jumlah telur terbanyak baik pada pemijahan individual maupun massal yaitu masing-masing 23-35 butir dan 83 butir, culex sp 19-30 butir dan 62 butir serta pakan pellet sebanyak 17-24 butir dan 43 butir. Hasil uji ANOVA menunjukkan tidak ada perbedaan yang signifikan antara jumlah telur dengan pakan.
A importância do pensamento de Thomas Ogden para a psicanálise contemporânea
Authors: Brinholli Fabio , Coelho Junior Nelson Ernesto
Published: September 2020

Resumo Este artigo apresenta a importância do pensamento de Thomas Ogden para a psicanálise contemporânea. Trata-se de um autor que tem como característica central um discurso e um modo de pensar que levam em conta as dimensões intrapsíquicas e intersubjetivas no campo psicanalítico. A experiência com a matriz clínica da esquizofrenia é o ponto de partida privilegiado para seus desenvolvimentos teóricos. Destacamos neste texto três grandes contribuições ao longo de sua obra: (a) o estado de não-experiência; (b) a posição autista-contígua; e (c) o terceiro-analítico.
A irrepetibilidade da arte
Authors: Rech Morgana , Ketzer Estevan de Negreiros
Published: September 2020

Resumo O artigo trata dos elementos ligados à repetição como característica da intencionalidade estética nas obras de arte. Mostramos como a repetição, acompanhada da reflexão freudiana acerca do estranho (Unheimlich), é evidenciada na necessidade do artista de repetir um novo encontro com a obra, na intenção de produzir um novo encontro com o mais radical de si. Ilustramos esta ideia com os aportes trazidos pela teoria estética contemporânea de Jacques Derrida e Georges Didi-Huberman, que observam o fenômeno da desvalia (désaisissement), certa restrição de visibilidade que causa uma cegueira do objeto. Apresentamos uma breve resenha clínica sobre um caso atendido por nós em que a vivência de emoções é obstaculizada, favorecendo o aparecimento de uma fala repetida na dimensão da clínica.
Construção de significados e ambiguidades na supervisão de estágio em psicologia
Authors: Silva Nádia Oliveira da , Pinheiro Marina Assis , Laurendon Candy Estelle
Published: September 2020

Resumo Na formação de psicólogos, o tripé supervisão-estágio-ensino é fundamental para o desenvolvimento de competências profissionais. Todavia a relação estreita entre estas três esferas ocasiona, por vezes, uma compreensão nebulosa sobre a práxis concernente a cada um destes campos. À luz do dialogismo bakhtiniano e da intersubjetividade, este artigo visa a analisar a construção de significados sobre supervisão de estágio, por meio das ambiguidades que enlaçam esta atividade. Foi possível analisar que as ambiguidades permeadas pelo tripé formativo ocasionam tensões nas relações intersubjetivas, sendo balizadoras na construção de novos significados sobre a atividade de supervisão. Estes significados são tecidos pela negociação com as outridades que permeiam essa atividade formativa e pelo contexto em que são realizadas. Isto posto, estudos desta natureza propiciam uma compreensão mais ampla sobre conhecimentos teóricos/práticos concernentes ao campo da supervisão, o que pode ensejar a construção de estratégias facilitadoras na formação de psicólogos.
O LADO MENOS CONHECIDO DA HISTÓRIA DA PRIMEIRA TRADUÇÃO DE GRANDE SERTÃO: VEREDAS PARA O INGLÊS
Authors: Pisetta Lenita Maria Rimoli
Published: September 2020

RESUMO A tradução de Grande sertão: veredas para o inglês, feita por Harriet de Onís e o Professor James Taylor e publicada no início da década de 1960, é em geral considerada insuficiente, não fazendo jus ao original de Guimarães Rosa. A parte mais conhecida da história dessa tradução é apresentada em trabalhos que têm como fonte principal as cartas trocadas entre Guimarães Rosa e Harriet de Onís, que estão no acervo JGR do Instituto de Estudos Brasileiros (IEB) da Universidade de São Paulo. Com base em trabalhos já publicados sobre o assunto e na análise de cartas trocadas entre a tradutora Harriet de Onís e os editores da Alfred A. Knopf, o objetivo deste trabalho é esclarecer melhor alguns fatos que parecem ter ficado em segundo plano, principalmente a atuação de Harriet de Onís para “defender” sua tradução e a escrita singular de João Guimarães Rosa. Como apoio para a discussão, recorreremos às autoras Pascale Casanova e Emily Apter e suas visões sobre a “Literatura Mundial”.
A INTERPRETAÇÃO DAS CORES NA PARATRADUÇÃO DE PARATEXTOS AUDIOVISUAIS - O VERMELHO NA SÉRIE LA CASA DE PAPEL
Authors: Matos Morgana Aparecida de
Published: September 2020

RESUMO A interdisciplinaridade que existe nos Estudos da Tradução permite vislumbrar e consolidar a ideia de paratradução e paratexto audiovisual. Ao saber que os paratextos são essenciais para a tradução e a interpretação, aborda-se aqui, sob os auspícios da paratradução, a relevância dos estudos das imagens apresentadas em tela. A cor vermelha predominante na série televisiva La Casa de Papel, da Netflix, conflui uma imagem subjetiva que corrobora com a compreensão do enredo. Assim, este artigo tem o objetivo de apresentar os caminhos necessários para conformar o estudo das cores - o vermelho especificamente - na paratradução de imagens. A confluência metodológica paratradutiva auxilia na busca de informações, as quais acabam por explicitar os adjetivos que descrevem as sensações do simbolismo da cor, vindouras e perpetuadas na compreensão geral da série que, de forma criativa e aculturada, foram apresentadas nos paratextos audiovisuais estudados.
IL RUOLO COGNITIVO DEI GESTI NELL'EDUCAZIONE LINGUISTICA
Authors: Iaco Moira De
Published: September 2020

RIEPILOGO Questo contributo intende fornire argomenti utili per comprendere l'efficacia cognitiva dei gesti nella didattica delle lingue. Muovendo dall'influenza dei gesti su processi cognitivi quali i processi attentivi, la memoria, il problem solving e il ragionamento, si giungerà a mostrare le funzioni che i gesti possono svolgere nell'educazione linguistica. Il fine è quello di evidenziare l'esigenza per i docenti L2 di diventare sempre più consapevoli dell'uso strategico dei gesti nella didattica.
"MEU AMIGO NIETZSCHE": OS PERIGOS DA LEITURA CRÍTICA EM UM MUNDO CONFORMADO
Authors: Gambassi Giulia Mendes
Published: September 2020

RESUMO O objetivo deste artigo é discutir o ensino de literatura no Brasil a partir da análise do curta-metragem Meu amigo Nietzsche (2012), que representa, a nosso ver, um discurso de resistência no cenário de crise democrática em que vivemos. O filme apresenta a história de Lucas, um menino da periferia de Brasília que encontra dificuldades de leitura na vida escolar e, advertido pela professora, tenta melhorar suas práticas por iniciativa própria. Ao se deparar com um exemplar de Assim falou Zaratustra (NIETZSCHE, [1883] 2011), Lucas parece desenvolver práticas de letramento crítico a partir de um processo de descoberta dos sentidos das palavras, que evoluiu para uma reflexão filosófica sobre o mundo a seu redor. Assim, a partir da análise de algumas cenas do curta-metragem, tencionamos refletir sobre a literatura e seu ensino, assim como sobre a recepção da leitura crítica em um mundo conformado.
Phases and tools for supply chain risk management: a systematic literature review
Authors: Gaspar Priscila Gomes Pereira , Ceryno Paula Santos , Ferrer Ana Luiza , Thomé Antônio Márcio Tavares
Published: September 2020

Abstract Supply chain risk management (SCRM) has been widely discussed in the academic literature and several models have been proposed in recent years, but there is a need for a model encompassing phases and tools for SCRM. This study presents a systematic literature review (SLR) of 254 abstracts and 68 full-text papers. The SLR made it possible to identify and define the main phases for the SCRM, as well as the tools proposed for each phase. There is a concentration of efforts in the phases of identification, assessment, and selection of risk management strategies and a limited number of studies in monitoring and controlling risks. The article offers a global SCRM framework, contributing to the theoretical discussions and a practical guide to implementation related to SCRM.
Evaluation of leaf and root absorptions of glyphosate in the growth of coffee plants
Authors: Barbosa Edimilson Alves , Silva Isabel Moreira da , França André Cabral , Silva Enilson de Barros , Matos Christiano da Conceição de
Published: September 2020

ABSTRACT Intoxication by dispersion of glyphosate droplets in coffee seedlings is common and, in addition to the problem of drift, there are reports of contamination of this herbicide to a nontarget plant via the rhizosphere. Hydroponics allows the comparison of the translocation of the glyphosate absorbed by the foliage or the roots and avoids the interaction with the soil, which could hamper the achievement of more accurate conclusions when it is absorbed by the root. Thus, the toxicity of glyphosate sublethal dosages in the initial growth of coffee plants in hydroponics was evaluated by applying four sublethal dosages in two different locations (solution and leaf). Fifty days after the application of the herbicide, the intoxication percentage and the growth of the coffee seedlings were evaluated. From the reduced dose of 115.2 g·ha-1 of glyphosate, height reductions, root length; number of leaves, dry mass of leaf, roots and total, leaf area, and leaf mass ratio were observed. The first two parameters were observed only in leaf application and the others via leaf and solution. The aerial part–root ratio system had an increase in herbicide sublethal dosages when applied to leaves and the ratio of leaf area and specific leaf area increased in both applications. Sublethal dosages of glyphosate applied to young coffee plants under hydroponic conditions impair their growth, and it is more accentuated with increasing doses and when the leaves, instead of the roots, absorb the herbicide.
Phytotoxicity in two sugarcane cultivars in the initial development as affected by selectivity to herbicides
Authors: Perego Ivonei , Duarte Júnior José Barbosa , Rosa Willian Bosquette , Gonçalves Júnior Affonso Celso , Queiroz Samara Brandão , Costa Antônio Carlos Torres da
Published: September 2020

ABSTRACT Sugarcane is a crop of great importance for human consumption, either for the production of sucrose or for the production of ethanol fuel. The objective of this work was to evaluate the phytotoxicity caused by the herbicides, the agronomic components in two sugarcane cultivars, at five evaluation times, during the 12-month and 18-month cultivation periods. The experimental design was randomized blocks with four replicates, in a 10 x 2 factorial scheme, with nine herbicides (tembotrione, mesotrione, clomazone, saflufenacil, 2,4 dichlorophenoxyacetic, fluroxypyr + picloram, metribuzin, isoxaflutole, sulfentrazone), two sugarcane cultivars (RB006995 and RB036153), and five evaluation times (7, 14, 21, 28 and 35 days after application – DAA). The most phytotoxic herbicides for the 12-month cultivation period in the cultivars RB036153 and RB006995 were clomazone and sulfentrazone. For 18-month cultivation period, the herbicides isoxaflutole, clomazone and sulfentrazone were the most phytotoxic, mainly for the cultivar RB006995. For most herbicides, phytotoxicity decreased along the days after application. The most selective herbicides for both cultivars and cultivation periods were tembotrione, mesotrione and fluroxypyr + picloram.
Association between oral hygiene and head and neck cancer in Brazil
Authors: Pereira Nayara Fernanda , López Rossana Mendoza , Toporcov Tatiana Natasha , Schmerling Cláudia Kliemann , Cicco Rafael De , Michel-Crosato Edgard , Biazevic Maria Gabriela Haye
Published: September 2020

ABSTRACT: Introduction: Poor oral hygiene, regular use of mouthwash and absence of visits to the dentist could correspond to potential risk factors for the development of head and neck cancer. Objective: The objective of this study was to determine whether oral hygiene is associated with the occurrence of oral cavity and head and neck cancer in a Brazilian sample. Method: The variables of oral hygiene condition, such as toothbrushing frequency, dental loss, need and use of prosthesis, and regular visit to the dentist in a case-control study were analyzed in patients from five hospitals in the state of São Paulo, Brazil, paired by gender and age, from the multicenter project Genoma do Câncer de Cabeça e Pescoço (GENCAPO). Results: The most frequent malignancies in the 899 patients included were those of the tongue border (11.41%) and tongue base (10.92%). The multivariable statistical analysis found odds ratio values: Brushing once 0.33 (95%CI 0.25 - 0.44); Brushing twice 0.42 (95%CI 0.35 - 0.52); Flossing always 0.19 (95%CI 0.13 - 0.27); Flossing sometimes 0.19 (95%CI 0.15 - 0.24); Bleeding 2.40 (95%CI 1.40 - 4.09); Prosthesis 1.99 (95%CI 1.54 - 2.56); Visiting the dentist 0.29 (95%CI 0.22 - 0.37); Good hygiene 0.21 (95%CI 0.17 - 0.27); Regular hygiene 0.20 (95%CI 0.15 - 0.25); number of missing teeth (6 or more) 3.30 (95%CI 2.67 - 4.08). Conclusion: These data showed that, in the population studied, indicators of good hygiene such as brushing teeth and flossing were protective factors for mouth and head and neck cancer, while bleeding and many missing teeth were risk factors.
Burnout and Well-Being Levels of Medical Students: a Cross-Sectional Study
Authors: Cazolari Priscila Gadelha , Cavalcante Matheus de Sousa , Demarzo Marcelo Marcos Piva , Cohrs Frederico Molina , Sanudo Adriana , Schveitzer Mariana Cabral
Published: September 2020

Abstract: Introduction: The presence of chronic stress, caused by the activities and demands of the medical course, can lead to what is called ‘burnout’, a syndrome characterized by three dimensions: emotional exhaustion, dehumanization (or depersonalization) and reduced professional achievement. Considering the increased incidence of burnout syndrome, anxiety and depression symptoms, suicide attempts and suicide rates among medical students, as a consequence of increasing demands for professional and financial success at the expense of physical and mental health, one understands the importance of studying the subject and proposing measures of prevention and control. The aim of this study was to evaluate and describe the levels of burnout and well-being of medical students at a Brazilian public university. Method: The stress and well-being levels of students from the first to the sixth year for the Medical Course at Universidade Federal de São Paulo were evaluated using MBI-SS and WHOQOL-BREF questionnaires, applied online on the REDCAP platform. Results: A total of 302 students completed the questionnaires. Regarding the MBI-SS, students showed a low value in the emotional exhaustion factor and high levels of professional disbelief and effectiveness, indicating a burnout that ranged from low to moderate. It was also observed that female students showed a greater tendency toward emotional exhaustion when compared to male ones, as well as the fact that students from the 1st and 2nd years showed higher values of professional effectiveness when compared with 3rd and 4th years, with no difference between genders. Based on the answers from WHOQUOL-BREF questionnaire, the students thought they had a good quality of life. Discussion: These results reinforce possible factors that might interfere with the students’ quality of life: excessive workload, teaching model based on extensive lectures, lack of stimulation, recognition for their efforts. Conclusion: The medical students evaluated in this study have a good quality of life and show low or moderate burnout levels.
Qualidade de Vida de Acadêmicos de Medicina: Há Mudanças durante a Graduação?
Authors: Pires Aline Maria Fatel da Silva , Gusmão Waléria Dantas Pereira , Carvalho Lucyo Wagner Torres de , Amaral Monique Maria Lucena do Suruagy do
Published: September 2020

Resumo: Introdução: O conceito de saúde está ampliado para além da ausência de doença e envolve atualmente todos os aspectos de qualidade de vida dos indivíduos, inclusive a percepção deles em relação à condição de vida, ao contexto cultural e ao sistema de valores sob os quais vivem. Método: Objetivou-se analisar a qualidade de vida dos acadêmicos de Medicina da Universidade Estadual de Ciências da Saúde de Alagoas (Uncisal) por meio do questionário World Health Organization Quality of Life abreviado (Whoqol-Bref) da Organização Mundial da Saúde. O Whoqol-Bref possui 26 questões, das quais duas são gerais sobre a qualidade de vida e a satisfação com a saúde, e 24 estão divididas em domínios: físico, psicológico, relações sociais e meio ambiente. As respostas são pontuadas de um a cinco, por grau de intensidade; após coleta, foram calculadas as médias dos escores e os domínios, os quais são convertidos em uma escala de 0 a 100. Resultados: Dos 188 acadêmicos, 62,03% consideraram sua qualidade de vida boa ou muito boa, enquanto 54,25% referiram estar nem satisfeitos nem insatisfeitos, insatisfeitos ou muito insatisfeitos com sua saúde. Além disso, nenhum dos grupos alcançou a “região de sucesso” na avaliação dos domínios, havendo diferença estatisticamente significante apenas do domínio físico (p = 0,02), em que se percebe uma melhora dos escores no decorrer do curso. Os alunos do primeiro e segundo anos tiveram pior avaliação nos domínios, demonstrando que a ansiedade e a expectativa sobre a graduação podem afetar negativamente a qualidade de vida. Em relação aos domínios, destaca-se o “sono e repouso” como a questão de pior avaliação, ocupando a “região de fracasso”, seguida da questão que avalia a oportunidade de lazer e recreação, provavelmente pelo fato de o processo de formação desgastante prejudicar também a saúde física, mental e emocional. Em relação ao sexo, as mulheres tiveram a pior avaliação em todos domínios e nas questões gerais, havendo diferença significativa no domínio psicológico (p = 0,04) e na satisfação com a saúde (p = 0,04). Conclusão: Portanto, faz-se necessário que se desenvolvam intervenções capazes de oferecer apoio aos acadêmicos de Medicina, de modo a ajudá-los a conseguir lidar com as dificuldades que enfrentarão durante o curso.
Máscaras sem rosto: Zaratustra como um mestre “pós-nietzschiano”
Authors: Cragnolini Mónica B.
Published: September 2020

Resumo Após uma breve passagem pela noção de máscara em Nietzsche, e sua ligação com a ideia de toda “identidade” possível, vamos analisar o lugar da máscara de Zaratustra como mestre, e os significados de seu “ensinamento”. Mostraremos como o ensino de Zaratustra é uma forma de não-ensinamento e, nesse sentido, indicaremos a forma como esse não-ensinamento se torna visível como tal em alguns problemas do pensamento contemporâneo.
Filosofia como forma de vida: variações sobre o tema a partir de Nietzsche e Sócrates
Authors: Pimenta Olímpio
Published: September 2020

Resumo Busca-se, a partir do exame dos compromissos existenciais implicados pela prática filosófica dos dois pensadores, estipular uma série de convergências entre ambos. Porque tal associação parece improvável, se se tem em vista o combate dado por Nietzsche a formulações substantivas do repertório filosófico tradicional talvez autorizadas por Sócrates, importará oferecer ao final um balanço da reflexão também quanto a isso.
Nietzsche: da análise psicológica à fórmula da décadence
Authors: Marton Scarlett
Published: September 2020

Resumo Tendo esclarecido a concepção nietzschiana de psicologia, este artigo persegue um duplo objetivo: de um lado, investigar a análise psicológica dos fenômenos da décadence e, de outro, elucidar o que significa a expressão “fórmula da décadence” nos textos de 1888.
DEPENDÊNCIA CULTURAL E MEMÓRIA DO ENSINO DE LÍNGUAS E LITERATURAS ESTRANGEIRAS NO BRASIL
Authors: Andrade Antonio
Published: September 2020

RESUMO Neste artigo discutimos a problemática da dependência cultural na memória discursiva que atravessa a relação entre o ensino de línguas e de literaturas estrangeiras no Brasil, com ênfase sobre o lugar singular ocupado pelo espanhol e as literaturas hispânicas neste contexto. Nossa investigação focaliza arquivos históricos do Colégio Pedro II, considerado escola-modelo da educação nacional desde o século XIX até meados do século XX.
THREE MILLENNIA OF CHINESE POETRY
Authors: Seng Anabela Fong Keng
Published: September 2020

Abstract Poetry has a history of thousands of years in China and can be said to be the shining jewel in the crown of Chinese literature, occupying a major proportion in her history. Having originated from folk songs, the Chinese poetry has produced a large number of brilliant examples from the Western Zhou Dynasty (1046-771 BC) to the Chunqiu (Spring and Autumn) Period (770-476 BC). China has, since ancient times, maintained a tradition of education in poetry, which is used to educate the people and arouse their intelligence. Through the reading, studying and writing of poetry, it is possible to instruct and cultivate the character of young pupils, as well as to promote children’s creative thinking, logical dialectics and humanistic consciousness. In addition, reciting, learning and writing poetry has the ability to cultivate one’s temperament, allowing people of all social strata, professional occupation and age to cleanse and purify their minds. The realm of poetry has the same effect of calming the soul as religious belief. This article shows the highlights of three millennia of Chinese poetry to the readers or scholars whose native language is not Chinese.
THE MUSEUM BRAZIL: CULTURAL CANNIBALISM AS AN ANSWER TO THE PREDICAMENTS OF A SHAKESPEAREAN CULTURE
Authors: Rocha João Cezar de Castro
Published: September 2020

Abstract: Shakespearean cultures are the ones whose self-definition heavily relies on the determination of a foreigner’s gaze, their self-perception originates in the gaze of an Other. Thus, in such circumstance, the centrality of the other demands the prominence of the mimetic impulse in the shaping of national identity, which cannot but evoke a paradoxical constellation, based upon a constant oscillation between the own and the foreigner.
PAINTING AND POETRY: EZRA POUND’S “SEVEN LAKES CANTO” AND EIGHT VIEWS OF XIAO XIANG
Authors: Jiang Hongxin
Published: September 2020

Abstract: In the history of cultural exchange between China and the West, it’s a deed praised far and wide that the Chinese paintings Eight Views of Xiao Xiang had exerted great influence on Ezra Pound’s poetic work “Seven Lakes Canto” or “Canto 49.” By exploring the details of the paintings and tracing the influence of the paintings on the creation of the poem, this paper reveals that the etymological and compositional use of Chinese ideograms had an enormous impact on Pound’s thinking about poetry and cultural matters, and on the writing of The Cantos. Pound, by adopting the images of China in Eight Views of Xiao Xiang, finds another paradise, so the Chinese cultural elements enabled him to create a new entity in its own right: the Poundian poem. Discussion of Pound’s “Seven Lakes Canto” from his poetic and translation theories certifies that the poem can actually be perceived as a unique way of interpreting and displaying China.
PÁGINAS DE RECORDAÇÕES: RETRATO DE UM BRASIL DO SÉCULO XX
Authors: Costa Monica Chagas da
Published: September 2020

RESUMO: A presente resenha apresenta uma leitura das memórias de Floriza Barboza Ferraz, nascida no século XIX no interior de São Paulo. A narrativa da própria vida permite à autora ressaltar alguns aspectos da vida de uma esposa e filha de fazendeiros do café. Dois dos elementos mais salientes de sua história como é contada nas Páginas são sua relação com os trabalhadores - escravizados no período de sua infância, ou assalariados e majoritariamente imigrantes em sua época de casada - e sua visão sobre a maternidade e suas dificuldades durante as primeiras décadas do século XX.
THE “CORDIAL MAN”: A LATIN AMERICAN CONCEPT IN THE BRAZILIAN ESSAY
Authors: Monteiro Pedro Meira
Published: September 2020

Abstract: This article analyzes Sérgio Buarque de Holanda’s Roots of Brazil (1936), a seminal book in the Brazilian essayist tradition. Discussion begins with the limits of Brazil’s search for national specificity, so as to consider Brazilian cultural formation as a projection of its colonial Iberian roots. In this context, the “cordial man” emerges as a metaphor for the lack of public space in Brazil. On the one hand, the cordial man is a product of turn-of-the-century debates on Latin American exceptionalism, a figure almost capable of withstanding the disillusions of the modern world. On the other hand, the cordial man offers Buarque de Holanda a window into the limits of democratic liberalism and the personalistic political traditions of Latin America: an impasse discussed at length but never resolved in Roots of Brazil. Ultimately, the book permits a deeper questioning of the collective pulses and individual desires that, together, form the matter to which populism would respond, a political form temporarily capable of meeting the people’s demands.
BRAZILIAN LITERARY CRITICISM AND HISTORIOGRAPHY
Authors: Souza Roberto Acízelo de , Jobim José Luís
Published: September 2020

Abstract: In Brazil literary studies, after scant manifestations in the colonial period, represented by the activity of literary academies founded in the 18th century only really expanded in the course of the 19th century. National literary production grew in quantity and quality, as did literary studies, which, on the one hand, were demanded by this production- that, after all, needed to be studied and evaluated -, but, on other hand, stimulated this creativity, as they established as a criterion of value the alignment of fiction, poetry and dramaturgy with the nationalist agenda. As a result, from the 1820s until the 1880s, literary studies in Brazil underwent a period of expansion and diversification. If in the 1800s literary education was conducted at high-school level, from the 1930s onwards university courses in literatures began to be established in Brazil. In this paper we will provide a short introduction to Brazilian literary criticism and historiography from its very beginnings to the present time.
CRÍTICA E CRISE: TEORIA DA LITERATURA E HISTÓRIA DA CRÍTICA
Authors: Santana Thiago
Published: September 2020

Resumo Resenha de Teoria da Literatura e História da Crítica: momentos decisivos, de Nabil Araújo. Discutirei, capítulo a capítulo, os problemas centrais tematizados no contexto da obra, buscando lançar luz sobre a rede de referências teóricas, críticas e filosóficas mobilizadas pelo autor.
LEITURA COMPARADA INTERAMERICANA DA LITERATURA AMERÍNDIA
Authors: Bernd Zilá
Published: September 2020

Resumo: Em seu último livro, Rita Olivieri-Godet desvela as vozes de mulheres ameríndias nas literaturas brasileira e quebequense, elaborando uma reflexão aprofundada e sensível sobre a obra de duas escritoras indígenas do Brasil e duas do Quebec.
IN THE MASK OF A MARTIAL ART FILM: A CHINESE FILM ADAPTATION OF WILLIAM SHAKESPEARE’S HAMLET
Authors: Ying Zhang
Published: September 2020

Abstract: The release of Chinese film director Feng Xiao Gang’s The Banquet in 2006 declares the first Chinese Hamlet film adaptation. Feng chooses to sinicize the play and interweaving cultural elements by framing the play into a Chinese martial art film and by applying Chinese Nuo mask and its variation in his filmic interpretation of the play. The frame of martial art film is heavily featured as the Chinese cultural touch deployed by the director in the transformation of a western play into a Chinese film, which proves to be an effective tool for displacing the western cultural elements with Chinese cultural ideology and principles. The use of the Nuo mask motif throughout the film is discussed with the following examples: 1. The director’s choice of using the Chinese Nuo mask in his adaptation of the play-within-the-play scene in the film, displacing the Mousetrap with its Nuo drama counterpart. 2. The director’s re-interpretation of Hamlet’s hesitation and madness, his representation of the Ghost and his symbolic approach to the building of characters by adopting a white paper mask. 3. The director’s transfer from the Ghost of Old Hamlet to copper carved mask symbolization. 4. The director’s building of characterization by using one’s own face as the mask. The framing of martial art film and the adoption of Nuo mask are the tools of sinicization in the process of the intercultural film adaptation of the western classic. The success of the film has explored the connections between the two cultures and challenged the transfer of Chinese culture into a western play.