bluuebunny/crossref_metadata_2025 huggingface dataset:
From Mission to Church: Nature, Spatiality, and Catholicism in Kikwit (DRC)
Authors: Feyaerts Mick
Published: January 2025

This study explores nature’s role in the spatial development of the local Roman Catholic Church in Kikwit, a mid-size city in the Democratic Republic of Congo. Founded as a mission station by Belgian Jesuits in 1912, the local Church has experienced a peculiar development over the last century. Roman Catholic communities seem grouped spatially according to their function. Communities with apostolic functions are located in the western part of the city, while contemplative and intellectual communities are concentrated in the eastern part. The dividing line appears to be the Kwilu River, which separates the lively commercial and residential center on the left bank from more rural municipalities on the right bank. This paper proposes that this spatial organization results from the interplay of multiple theologies of nature that led to different ways of engaging with the natural surroundings in the region. Moreover, the research suggests that the Catholic Church’s transformation from a missionary institution to a (more or less) independent Church in Kikwit relied heavily on nature because it allowed further development of both the apostolic and contemplative functions of the Church.
The Westward Spread of Eastern Learning: Jung’s Integration and Adaptation of Religious Daoism
Authors: Chen Ming
Published: January 2025

The impact and influence that a religious tradition can have amongst culturally out-group populations can be quite unexpected and can even “boomerang” back home in equally unpredictable ways. This article explores one example of a Chinese religion’s unexpected cultural influence within the Western psychiatric community using religious Daoism and its appropriation by analytical psychologist Carl Jung. Although elements of religious Daoism, such as Daoist Internal Alchemy or the Yijing, integrated into a system of psychiatric practices, its influence was not straightforward. It will be argued that Jungian ideas such as active imagination, individuation, and synchronicity were directly influenced or inspired by Jung’s exposure to religious Daoism through Richard Wilhelm, Daoist texts, and his own adoption of Daoist Internal Alchemy techniques, an influence which would reverberate through both Western and Chinese popular culture.
Corporate Social Responsibility, Efficiency, and Risk in US Banking
Authors: Jouini Fathi , Chouchen Mohamed Amine , Messai Ahlem Selma
Published: January 2025

Banks have faced increasing attention regarding their ability to balance Corporate Social Responsibility (CSR) initiatives, operational efficiency, and credit risk management, particularly in the wake of global financial challenges. This study examines the interplay between CSR, efficiency, and credit risk in 131 US banks from 2010 to 2018. Using the Choquet integral, two-step Data Envelopment Analysis, and a dynamic panel with the Generalized Method of Moments, the findings reveal a virtuous circle between CSR and credit risk, where CSR enhances credit risk profiles. Similarly, efficiency and risk exhibit mutual reinforcement. However, a vicious circle is identified between CSR and efficiency, indicating trade-offs between CSR objectives and operational efficiency. These insights guide policymakers and bank managers in optimizing this balance.
A Novel Ultrasound Thermometry Method Based on Thermal Strain and Short and Constant Acoustic Bursts: Preliminary Study in Phantoms
Authors: Gachouch Omar , Giammarinaro Bruno , Kangot Teymour , Monini Caterina , Souchon Rémi
Published: January 2025

In the field of ultrasound therapy, the estimation of temperature to monitor treatments is becoming essential. We hypothesize that it is possible to measure temperature directly using a constant acoustic power burst. Under the assumption that the acoustic attenuation does not change significantly with temperature, the thermal strain induced by such bursts presents a linear relation with temperature. A mathematical demonstration is given in the introduction. Then, simulations of ultrasound waves in a canine liver model were conducted at different temperatures (from 20 °C to 90 °C). Finally, experimental measurements on phantom samples were performed over the same temperature range. The simulation and experimental results both showed a linear relation between thermal strain and temperature. This relation may suggest the foundation of a new ultrasound-based thermometry method. The potential and limitations of the method are discussed.
An Optimization Coverage Strategy for Wireless Sensor Network Nodes Based on Path Loss and False Alarm Probability
Authors: Guo Jianing , Sun Yunshan , Liu Ting , Li Yanqin , Fei Teng
Published: January 2025

In existing coverage challenges within wireless sensor networks, traditional sensor perception models often fail to accurately represent the true transmission characteristics of wireless signals. In more complex application scenarios such as warehousing, residential areas, etc., this may lead to a large gap between the expected effect of actual coverage and simulated coverage. Additionally, these models frequently neglect critical factors such as sensor failures and malfunctions, which can significantly affect signal detection. To address these limitations and enhance both network performance and longevity, this study introduces a perception model that incorporates path loss and false alarm probability. Based on this perception model, the optimization objective function of the WSN node optimization coverage problem is established, and then the intelligent optimization algorithm is used to solve the objective function and finally achieve the optimization coverage of sensor nodes. The study begins by deriving a logarithmic-based path loss model for wireless signals. It then employs the Neyman–Pearson criterion to formulate a maximum detection probability model under conditions where the cost function and prior probability are unknown, constraining the false alarm rate. Simulated experiments are conducted to assess the influence of various model parameters on detection probability, providing comparative analysis against traditional perception models. Ultimately, an optimization model for WSN coverage, based on combined detection probability, is developed and solved using an intelligent optimization algorithm. The experimental results indicate that the proposed model more accurately captures the signal transmission and detection characteristics of sensor nodes in WSNs. In the coverage area of the same size, the coverage of the model constructed in this paper is compared with the traditional 0/1 perception model and exponential decay perception model. The model can achieve full coverage of the area with only 50 nodes, while the exponential decay model requires 54 nodes, and the coverage of the 0/1 model is still less than 70% at 60 nodes. According to the simulation experiments, it can be basically proved that the WSN node optimization coverage strategy based on the proposed model provides an effective solution for improving network performance and extending network lifespan.
LSTM–Transformer-Based Robust Hybrid Deep Learning Model for Financial Time Series Forecasting
Authors: Kabir Md R. , Bhadra Dipayan , Ridoy Moinul , Milanova Mariofanna
Published: January 2025

The inherent challenges of financial time series forecasting demand advanced modeling techniques for reliable predictions. Effective financial time series forecasting is crucial for financial risk management and the formulation of investment decisions. The accurate prediction of stock prices is a subject of study in the domains of investing and national policy. This problem appears to be challenging due to the presence of multi-noise, nonlinearity, volatility, and the chaotic nature of stocks. This paper proposes a novel financial time series forecasting model based on the deep learning ensemble model LSTM-mTrans-MLP, which integrates the long short-term memory (LSTM) network, a modified Transformer network, and a multilayered perception (MLP). By integrating LSTM, the modified Transformer, and the MLP, the suggested model demonstrates exceptional performance in terms of forecasting capabilities, robustness, and enhanced sensitivity. Extensive experiments are conducted on multiple financial datasets, such as Bitcoin, the Shanghai Composite Index, China Unicom, CSI 300, Google, and the Amazon Stock Market. The experimental results verify the effectiveness and robustness of the proposed LSTM-mTrans-MLP network model compared with the benchmark and SOTA models, providing important inferences for investors and decision-makers.
Fighting Disinformation Online: The Digital Services Act in the American Context
Authors: Peterka-Benton Daniela
Published: January 2025

The internet is one of humanity’s most significant creations in the modern era. What began roughly 30 years ago has developed into a rich, diverse, but largely unregulated environment we can no longer live without. With the spread of mis- and disinformation worldwide, calls for a safer internet have gotten louder. This article discusses the threats disinformation poses to online users and provides a case study on how the European Union’s Digital Services Act attempts to protect users’ fundamental rights in the online space and whether the Digital Services Act could or should serve as a model for similar legislation in the United States.
Adsorption–Desorption Behaviors of Enrofloxacin and Trimethoprim and Their Interactions with Typical Microplastics in Aqueous Systems
Authors: Li Zhichao , Meng Xiao , Shi Xiaoyong , Li Chunyue , Zhang Chuansong
Published: January 2025

Microplastics can transfer antibiotics in water through adsorption and desorption, causing adverse effects on the water environment. Therefore, understanding the interaction between microplastics and antibiotics is important in order to assess their impact on the environment. In this study, the adsorption–desorption behaviors of two commonly used antibiotics [enrofloxacin (ENR) and trimethoprim (TMP)] in aquaculture and their interactions with three typical microplastics [polystyrene (PS), polyvinyl chloride (PVC), and polyethylene (PE)] were investigated through laboratory experiments. The results showed that the adsorption capacity of the three microplastics was 1.229–1.698 mg/g for ENR and 1.110–1.306 mg/g for TMP, correlating with the octanol–water partition coefficients (logKow) of antibiotics. Due to the larger specific surface areas and special functional groups of microplastics, the antibiotic adsorption capacity of PS and PVC was higher than that of PE. The adsorption behavior followed pseudo-second-order kinetics and a Freundlich isotherm model, indicating a non-uniform surface with multilayer adsorption. A thermodynamic analysis showed that these were all spontaneous endothermic adsorptions. X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared spectroscopy (FTIR) analyses indicated that the adsorption mechanism was dominated by physical adsorption, involving π–π conjugation, halogen bonds, hydrogen bonding, and electrostatic interactions. High salinity and alkaline environments were conducive to desorption, and the ENR and TMP desorption rates of the microplastics ranged from 20.65% to 24.95%. This indicates that microplastics adsorbed with antibiotics will desorb antibiotics when entering the seawater system, thereby affecting marine ecosystems. These findings reveal the interaction mechanism between microplastics and aquaculture antibiotics in aqueous systems, providing theoretical support for environmental protection and sustainable development.
Evaluating the Effect of BMIs on Wound Complications After the Surgical Closure of Pressure Injuries
Authors: Garg Stuti P. , Sandepudi Kirtana , Shah Krish V. , Putnam Geneviève L. , Chintalapati Namrata V. , Weissman Joshua P. , Galiano Robert D.
Published: January 2025

Background/Objectives: Pressure injuries (PIs) are injuries to the skin and underlying tissue localized over a bony prominence. Surgical complications following the closure of a PI include ulcer recurrence, wound dehiscence, hematomas, and infection, which pose significant morbidity issues to patients. The objective of this study is to characterize the relationship between BMI and early and late wound outcomes following surgical closure through a secondary analysis of a previous study examining the effect of two support surfaces on PI healing. Methods: A single institution study on patients with a stage 3/4 pressure injury admitted for surgical closure was conducted. The subjects were monitored for 14 days post-closure (POD-14) so that an assessment of their early wound status and complications, including moisture, maceration, drainage, dehiscence, epidermolysis, necrosis, and demarcation, could be conducted. Results: In total, 68 patients were included. Out of these, 13% of patients were underweight, 29% were normal-weight, 35% were overweight, and 22% were obese. POD-14 complications occurred in 22% of underweight patients, 15% of normal-weight patients, 38% of overweight patients, and 40% of obese patients. Of all recorded complications, 75% of patients were overweight or obese. Complication rates were not significantly different based on osteomyelitis status. The most common cultures identified in wounds were P. aeruginosa, S. aureus, and E. coli. Negative cultures were found in 22% of closed wounds and 13% of open wounds. Conclusions: Our findings suggest that BMIs may be correlated with early wound status and the incidence of postoperative complications, while it may not be correlated with osteomyelitis status. Future studies should further evaluate the effect of BMIs on pressure injury-associated complications. This may further guide preoperative planning and patient expectations.
Sugar Asymmetry: The Evolution of De Novo Asymmetric Syntheses of Carbohydrates from Hexoses to Oligosaccharides
Authors: Hicks Ian , Kim Sugyeom , Sridhar Aneesh , O’Doherty George A.
Published: January 2025

The ability to recognize hidden symmetry in a highly asymmetric world is a key factor in how we view and understand the world around us. Despite the fact that it is an intrinsic property of the natural world, we have an innate ability to find hidden symmetry in asymmetric objects. The inherent asymmetry of the natural world is a fundamental property built into its chemical building blocks (e.g., proteins, carbohydrates, etc.). This review highlights the role of asymmetry in the structure of the carbohydrates and how these stereochemical complexities present synthetic challenges. This survey starts with an overview of the role synthetic chemistry plays in the discovery of carbohydrates and their 3D structure. This review then introduces various de novo asymmetric synthetic approaches that have been developed for the synthesis of carbohydrates and, in particular, oligosaccharides. The two most successful strategies for oligosaccharide synthesis rely on diastereoselective palladium-catalyzed glycosylation. The first uses an Achmatowicz reaction to asymmetrically prepare pyranose building blocks along with a substrate-controlled Pd-glycosylation. The other strategy couples a ligand-controlled Pd-glycosylation with a ring-closing metathesis for oligosaccharide assembly.
Catalytic Effects of Different Metal Salts on Cotton Waste Textiles by Pyrolysis: Pyrolysis Behavior and Properties of Activated Carbon
Authors: Zhang Yixiao , Zhao Xingjie , Chen Si
Published: January 2025

This study was conducted to explore the catalytic effects of different metal salts on the pyrolysis behavior of cotton waste textiles (CWTs) and the properties of their activated carbons (ACs). The decomposition characteristics of CWTs with Zn, Fe, and Cu salts were studied by thermogravimetric analysis (TGA) to analyze the catalytic effects. The physical and chemical characteristic differences of the ACs were detected with SEM-EDS, BET, FTIR, and XPS. The results show that metal salts reduced the decomposition temperature of the CWTs and improved the pore structures and specific surface areas of the activated carbons (ACs). The ACs produced abundant acidic surface functional groups on their surfaces, which facilitated the selective adsorption of pollutants. This study indicates that cotton waste textile biochar treated with metal salts may be a promising adsorbent for the removal of heavy metals and organic pollutants.
Exploring the Molecular Composition of Dissolved Organic Matter and Its Connection to Microbial Communities in Industrial-Scale Anaerobic Digestion of Chicken Manure
Authors: Hu Juan , Zeng Yurui , Hu Aibin , Wang Xiaofeng
Published: January 2025

Anaerobic digestion (AD) technology offers significant advantages in addressing environmental issues arising from the intensification of livestock production since it enables waste reduction and energy recovery. However, the molecular composition of dissolved organic matter (DOM) and its linkages to microbial biodiversity during the industrial-scale AD process of chicken manure (CM) remains unclear. In this study, the chemical structure of CM digestate-derived DOM was characterized by using multi-spectroscopic techniques and ultrahigh-resolution mass spectrometry, and the microbial composition was detected by using 16S rRNA gene sequencing. The results revealed that the DOM contained abundant free amino acids and protein-like compounds but fewer humic-like substances, identified as lignin/carboxylate-rich alicyclic molecules, lipids, and proteins/aliphatic compounds featuring enriched S5–6O1 and N1–5OX fragments. In addition, the 16S rRNA results revealed microorganisms that were centered on metabolic function in the production of volatile fatty acids, H2S/CH4, and the hydrolysis reaction in the AD process. Free amino acids and protein-like compounds were mainly associated with hydrolysis reactions and H2S production functional microorganisms. Lignin/carboxylate-rich alicyclic molecules were linked to microorganisms possessing hydrolysis reactions and, indirectly, CH4 production. This study elucidates the linkage with the microbial and molecular composition of DOM, establishing a theoretical foundation for employing AD in the disposal of CM.
Control of Neonatal Diarrhea in Piglets with Reduced Antibiotic Use by Application of a Complementary Feed—A Randomized Controlled Farm Trial
Authors: Sall Klaus K. , Foldager Leslie , Delf Charlotte , Christensen Sigurd J. , Agerley Michael N. , Havn Kristian T. , Pedersen Carsten
Published: January 2025

The objective of this farm trial was to investigate if the consumption of antibiotics could be reduced when piglets showing early signs of neonatal diarrhea were treated with an oral dose of tannin extract derived from sweet chestnut wood. The farm had a very high incidence of neonatal diarrhea among gilt litters. Gilts were randomized into test or control groups in a 1:1 ratio to compare the consumption of antibiotics used for piglets and piglet mortality during the four-week trial period. Control litters were treated with the oral antibiotic paromomycin, while test litters were treated with the complementary feed O-Nella-Protect. The farm trial included 18 gilt litters comprising 254 piglets. In the control group, 100% of the piglets received antibiotic treatment. In the test group, consumption of antibiotics used against diarrhea was reduced by 84% (p = 0.001) and consumption of antibiotics used for other illnesses was reduced by 45% (p = 0.045). In both test and control groups, six piglets died. Microbiological analysis identified both potential bacterial and viral pathogens. In conclusion, the farm trial indicates that even under the challenge of potentially serious bacterial and viral pathogens, a complimentary feed containing a tannin extract can support piglet health and reduce antibiotic consumption.
Colour Vision Deficits in Children with Amblyopia: Impact of Angular Size of Stimuli on Detection
Authors: Kalnica-Dorosenko Kristine , Litavnieka Anzelika , Truksa Renars , Svede Aiga , Valeina Sandra
Published: January 2025

This study investigates colour vision deficits in children with amblyopia by employing a computerized colour vision test with varying stimulus sizes (1°, 2°, and 3°). The aim is to delineate the impact of amblyopia on colour discrimination in children and to determine the effectiveness of the computerized colour vision test in detecting these deficits. The study involved 40 participants, divided into 20 children with amblyopia and 20 without amblyopia (control group). Our findings reveal that, during binocular viewing, children with amblyopia exhibit significant impairments in colour vision both for red–green and blue–yellow axes, primarily for 1° chromatic stimuli, but not for larger stimuli (2° and 3°). These findings offer valuable insight into the functional visual limitations in pediatric amblyopia, potentially guiding more targeted clinical assessments and interventions.
Optimizing Irrigation Regimes for Peanuts in Water-Scarce Regions: A Case Study in Western Liaoning, China
Authors: Zhao Siyuan , Du Xinhao , Chen Jing , Chen Dan , Luo Zhaohui , Bi Bo , Liu Haoran , Lin Lan , Wei Huanghuang
Published: January 2025

Scientific irrigation scheduling is crucial for conserving agricultural water resources, as excessive irrigation diminishes crop yield and imprecise water application can equally reduce water use efficiency (WUE). In Western Liaoning Province, China, where water scarcity is critical, traditional irrigation regimes are commonly used for peanut cultivation, with local farmers applying water without considering actual crop water demands, thereby reducing water efficiency and yield. In this study, field experiments on peanuts were conducted from May to October during 2021 and 2022 in Heishan County, Western Liaoning Province, China. Four irrigation regime treatments for micro-sprinkler irrigation, with different lower limits of soil water content, were applied: T1 (55% field capacity), T2 (65% field capacity), T3 (75% field capacity), and T4 (85% field capacity). The plant height, stem thickness, root length, dry matter weight, yield, WUE, and net return were measured. Different irrigation regimes had significant effects on peanut growth. The yield was highest in the T3 treatment in 2021 at 5574 kg·hm−2. Moderate irrigation could improve the yield, but it was difficult to simultaneously achieve a high WUE. The WUE of the T3 treatment was 5% lower than that of the T2 treatment in 2022, where the WUE was the highest at 1.62 kg·m−3. The highest net return was observed in the T3 treatment at 27,307 yuan·hm−2. The T3 treatment, with the highest similarity degree of 0.83 as determined with the entropy value and TOPSIS method, was evaluated as the optimal irrigation regime. This regime not only exhibited a favorable balance of water use efficiency and yield but also maximized economic benefits, making it a recommendable practice for local peanut irrigation.
A Laboratory Investigation into the Effect of Coarse-Grained Layer Mixing with Fine Particles on the Water Storage Capacity of a Capillary Barrier Cover
Authors: Sun Chong , Yang Junjie , Liu Qiang , Wu Yalei , Miao Jiali
Published: January 2025

A capillary barrier cover (CBC) is a geotechnical structure which a coarse-grained soil layer covered by a fine-grained soil layer. A CBC can retain downward water infiltration, increase water storage capacity and lateral diversion, and prevent capillary rise. Geotextiles are usually set up as isolation layers between fine-grained and coarse-grained layers to prevent fine particles entering the coarse-grained layer, resulting in a decrease in downward water infiltration and water storage capacity. However, crustal stress, farming, animal, plant activities, and other factors may cause damage to the isolation layer. At present, there is no reliable and accurate method to determine the location and degree of damage to the isolation layer. The existing methods search for the damage location by excavating the whole fine layer, which incurs high maintenance costs. If the damaged position of the CBC isolation layer can be accurately obtained, it can reduce maintenance costs. Therefore, this study investigated the influence of a coarse-grained layer mixed with different particle sizes and proportions of fine particles on water storage capacity through laboratory soil column experiments. The results are as follows: (1) Fine particle mixing into the coarse-grained layer will reduce water storage capacity, and there is a worse admixture ratio that minimizes water storage capacity. (2) The CBC enhances the fine-grained layer volumetric water content (VWC), but the enhancement degree decreases as the distance from the fine–coarse interface increases. (3) A method has been proposed to determine the location and degree of damage to the isolation layer. When the VWC at the fine–coarse interface reaches a stable level during breakthrough, the CBC effect exists, the higher the VWC at the fine–coarse interface, the stronger the CBC; when the VWC at the fine–coarse interface is unstable during breakthrough, the CBC effect disappears, and the median diameter of the fine particles mixed into the coarse-grained layer is finer than or equal to the fine-grained particles’ median diameter.
Internationalisation of curriculum: Analysis of subjects within the Faculty of Arts and Education at a regional Australian university
Authors: Krautloher Amita , Jha Meena
Published: January 2025

A regional university in Australia is dedicated to developing 21st-century graduates as global citizens. The curriculum is designed to equip students with the knowledge and skills necessary for success in a globalised world. Assessing whether students are truly becoming ‘global citizens’ involves evaluating not just academic performance, but also intercultural competencies, global awareness, and adaptability. Immediate, tangible outcomes like job placements can take precedence over long-term goals like global readiness. There are many factors that hinders a comprehensive review of whether the curriculum is effectively preparing students to become global citizens. There has not been any systematic understanding of the research status of the internationalization of the curriculum (IoC). This paper reports on the experiences of academics and students regarding the internationalisation of the curriculum within the Faculty of Arts and Education (FoAE). A mixed-method approach was adopted over two years, involving surveys and one-on-one interviews with academics and students. Thematic analysis of the responses revealed both strengths and areas for improvement for integrating IoC in higher education institutions. While academics and students value an internationalised curriculum, it is inconsistently implemented across the curriculum and there is a need for universities to establish a clear framework or benchmark for evaluating the internationalisation of their curriculum to assess progress systematically. The study's findings offer valuable insights for enhancing the internationalisation of the curriculum and improving the effectiveness of academic staff in delivering globally relevant content. This could lead to a stronger institutional reputation, attract a more diverse and international student cohort, and has capability to positively impact the university's financial sustainability by aligning the curriculum with global education trends.
Effect of NPK, bulb size and spacing on yield of pran (top onion) under temperate rainfed conditions
Authors: Saleem Tahir , Sultan Tariq
Published: January 2025

The present investigation was carried out at the experimental field of the Division of Vegetable Science, Sher-e-Kashmir University of Agricultural Sciences & Technology of Kashmir, Shalimar during for ascertaining suitable spacing, bulb size and NPK combination for maximizing yield and quality of Top onion (Pran). The experiment comprising of 27 treatment combinations was laid out as a randomized complete block design with each treatment combination replicated three times. Three bulb sizes (2.5-5.0, 5.1-7.5 and 7.6-10.0g), three spacings (20 x 10, 20 x 15 and 20 x 20 cm) and three NPK fertilizer levels (80:60:40, 100:80:60 and 120:100:80 NPK kg ha-1) in various combinations were tried in the experiment. The findings reveal that among various treatment combinations, F3B3S3 combination (120:100:80 NPK kg ha-1 , 7.6-10.0g bulbs and 20 x 20 cm spacing) recorded highest values for number of bulbs (8.72), bulb length (6.73cm), bulb diameter (2.79cm), bulb weight (16.44g), bulb weight per plant (141.75g). However highest yield per hectare (37.72 t ha-1) was recorded for F2B2S2 treatment combination (100:80:60 NPK kg ha-1, 5.1-7.5g bulbs and 20 x 15cm spacing).
Critiquing the representation of life and death in Christopher Nolan's Oppenheimer (2023): an ethical perspective
Authors: Malik Garima
Published: January 2025

Since the start of the atomic age, the value of life and gravity of mass deaths have been severely undermined in narratives on/related to the nuclear bombings. Christopher Nolan's Oppenheimer similarly fails to address many critical ethical perspectives regarding representation of life and death. The paper explores the movie's treatment of life and death and the underlying philosophy of nuclearism, which devalues the lives of the 'other', and shapes the 'sublime' representations of atomic bomb scientists and the science behind the bomb. The eulogization of the atomic bomb science and its scientists create a worldview that prioritizes violence over life and death of the 'other' who are victims of that violence. To contrast and represent an alternative outlook, a philosophy which prioritizes life and acknowledges the weight of mass deaths, as is appropriate for narratives on/related to mass atrocities like Hiroshima and Nagasaki, is explored. This philosophy is explored through a comparison with Japanese atomic bomb literature, which provides the victim's perspective. The comparison highlighting the differing perspectives of representations on a very crucial issue.  The paper concludes with importance of embodying suffering of the victims in representations and giving weightage to death and mourning to emphasize the value of life. The analysis of the issue is also important as cultural representations influence the public's acceptance or rejection of nuclear weapon and its developments, indirectly shaping whether further suffering is inflicted on the world or peace prevails.
Psicofarmacologia moderna: o impacto dos avanços terapêuticos na psiquiatria atual
Authors: Ribeiro Pedro José Targino , Bonfim Bárbara Vilani Bezerra , Martins Lucy Ana Lemos de Figueiredo , Alves Bruno Sousa , Pessoa Danielle Felix de Freitas , Mota Gabriel Gonçalves Bastos , Machado Caila Marília Maciel , Colaço Italo Vilela
Published: January 2025

Introdução: A depressão, um transtorno mental altamente prevalente, representa um desafio significativo para o manejo clínico, principalmente em casos de resistência aos tratamentos convencionais. Nos últimos anos, avanços em psicofarmacologia têm ampliado as opções terapêuticas por meio de fármacos inovadores, como antagonistas NMDA, psicodélicos e medicamentos multimodais. Objetivo: Revisar os avanços recentes em terapias farmacológicas para depressão, com foco em eficácia, segurança e limitações. Metodologia: Foi realizada uma revisão integrativa de artigos publicados entre 2019 e 2024, coletados nas bases de dados Scielo, Pubmed e BVS. Os descritores utilizados incluíram termos relacionados à depressão e novas terapias farmacológicas, aplicados em português e inglês. A análise descritiva e avaliativa dos dados foi realizada com base nos critérios de inclusão previamente definidos. Resultados: A esketamina demonstrou redução rápida dos sintomas depressivos, especialmente em pacientes com alto risco suicida. A psilocibina apresentou efeitos prolongados e melhorias na qualidade de vida, enquanto medicamentos multimodais, como a vortioxetina, combinaram benefícios antidepressivos e cognitivos. Contudo, desafios como custos elevados, efeitos adversos e a necessidade de supervisão terapêutica foram evidenciados. Conclusão: As inovações em psicofarmacologia representam uma evolução significativa na psiquiatria, oferecendo novas perspectivas para o tratamento da depressão. Apesar disso, estudos adicionais e estratégias para superar barreiras de acessibilidade são essenciais para consolidar essas abordagens.
Potencial biotecnológico e nutracêutico da polpa in natura, amêndoa e óleo da pupunha, proveniente de Santarém – PA
Authors: Ferreira Mikael dos Santos , Castro Thamy Fernanda de Sousa , Uchôa Brenda Campos , Silva Beatriz Almada da , Machado Lucas Campos , Sá Thais Cristina de , Oliveira Zandleme Birino de , Silva Júnior Antônio Quaresma da
Published: January 2025

A pupunheira é uma espécie de palmeira nativa da Amazônia, sendo bastante cultivada na região. Considerando que o fruto é rico em nutrientes, sua produção gera renda para as famílias locais, o que resulta em benefícios tanto financeiros quanto nutracêuticos. Este trabalho visa avaliar o potencial biotecnológico e nutracêutico da pupunha oriunda de Santarém-Pará, através do desenvolvimento de produtos alimentícios e cosméticos que utilizem o fruto da pupunheira. Os frutos da pupunha foram obtidos em uma feira livre, em Santarém, Pará. Após a obtenção das amostras, a polpa foi separada da amêndoa e ambas foram extraídas manualmente e triturada. A composição centesimal da polpa, amêndoa e farinha da pupunha foi realizada por meio das determinações de umidade, cinzas, proteínas, lipídeos e carboidratos. Uma formulação base foi preparada seguida da incorporação de óleo da pupunha, obtido a partir do método de determinação de lipídios (Bligh- Dyer). Para produção do creme. Testes de ph, centrifugação, viscosidade, espalhabilidade, e antioxidante foram realizados para avaliar a estabilidade das amostras em 0 e 30 dias. A polpa, amêndoa e farinha apresentaram-se rico em nutrientes com valores mais relevantes de: carboidratos (15,27; 27,11e 65,11%), lipídeos (7,90; 6,58 e 23,98%) e proteínas (4,42; 4,18 e 5,18%), respectivamente. As formulações apresentaram ausência de alterações nos testes de centrifugação, cor e odor, boa espalhabilhidade, pH ligeiramente ácido, viscosidade entre 77,600 e 88,850, e altos níveis de antioxidantes, com destaque para o óleo e farinha da pupunha.  Dessa forma, chegou-se à conclusão de que a polpa, a amêndoa e a farinha têm um alto valor nutricional e antioxidante, o que a torna um produto benéfico para a saúde sob diversos aspectos.
Pseudo-hipoparatireoidismo com ossificação ectópica: relato de caso
Authors: Coelho Ana Luiza Bittencourt , Silva Gabriela Thiago Gontijo da
Published: January 2025

O pseudo-hipoparatireoidismo (PHP), considerado uma endocrinopatia hereditária rara, é uma doença caracterizada pela resistência do organismo à ação do paratormônio (PTH), associado a hipocalcemia e hiperfosfatemia. A prevalência exata da doença ainda é desconhecida. O objetivo deste trabalho é relatar um caso de pseudo-hipoparatireoidismo e seu manejo na prática clínica. Trata-se de uma paciente do sexo feminino, 19 anos, que foi encaminhada ao ambulatório de endocrinologia para investigação de lesões cutâneas calcificadas na pele, início das lesões desde a primeira infância. Ainda, além das lesões de pele, ao exame físico paciente apresentava baixa estatura, sobrepeso, faces redondas, braquidactilia, história prévia de hipotireoidismo. Exames laboratoriais com níveis elevados de PTH, hiperfosfatemia e hipocalcemia, biópsia de lesão cutânea sugestiva de osteoma cutis. Conforme os achados fenotípicos e bioquímicos, realizado diagnóstico de PHP. Por ser uma doença complexa, rara e com apresentação clínica heterogênea, o diagnóstico do PHP muitas vezes é tardio. A análise molecular possibilita diferenciar os seus subtipos. A meta do tratamento é manter os níveis séricos de cálcio e fósforo dentro da normalidade através da reposição de cálcio e vitamina D e evitar a hipercalciúria. Quando atingido os objetivos, complicações agudas e crônicas da hipocalcemia podem ser evitadas.
Aplicabilidade do uso de inibidores de SGLT2 no paciente portador de insuficiência cardíaca
Authors: Gomes Ana Luísa , Dias Amanda Ribeiro , Pidde Arthur Gomes , Pidde Áurea Gomes , Marques Ketholyn Andrade , Gomes Cecília Martins , Siqueira Susan Gonçalves Oliveira Mendes , Gonçalves Vitória Caldas
Published: January 2025

A aplicabilidade dos inibidores de SGLT2 no tratamento da insuficiência cardíaca (IC), tem como foco as evidências científicas recentes e a experiência clínica. A insuficiência cardíaca, uma condição comum e complexa, é caracterizada pela incapacidade do coração de bombear sangue adequadamente, comprometendo a função de órgãos vitais. Embora os inibidores de SGLT2 tenham sido inicialmente desenvolvidos para o tratamento do diabetes tipo 2, estudos recentes demonstraram que esses fármacos proporcionam benefícios adicionais, como a redução da mortalidade cardiovascular e hospitalizações por insuficiência cardíaca, especialmente em pacientes com fração de ejeção reduzida. O mecanismo de ação desses medicamentos envolve a inibição da reabsorção de glicose nos rins, mas seus efeitos benéficos também incluem a redução da pressão arterial, a melhora da função endotelial e a diminuição da inflamação sistêmica. Ensaios clínicos, como DAPA-HF e EMPEROR-Reduced, evidenciam esses benefícios. A experiência clínica relatada, baseada no acompanhamento de pacientes internados, demonstrou que a utilização de inibidores de SGLT2 resulta em uma melhora significativa nos sintomas, qualidade de vida e redução das hospitalizações. Embora os resultados sejam promissores, a individualização do tratamento e o monitoramento contínuo são essenciais. Conclui-se que os inibidores de SGLT2 são uma opção terapêutica valiosa no manejo da insuficiência cardíaca, alinhando-se às diretrizes mais recentes e apresentando um impacto positivo no prognóstico dos pacientes.
Caracterização de lesão por pressão em pacientes pediátricos em um hospital público universitário
Authors: Zawadzki Sabrina Aparecida Iglicoski , Oliveira Lucas Borges de , Cardoso Sandra Maria Schefer , França Francisca Elaine de Souza , Maier Cinthia Tiemy Cardoso , Souza Thaluana Selvero de , Visgueira Angela Freire
Published: January 2025

Objetivo: caracterizar as lesões por pressão em pacientes pediátricos internados em um Hospital Público Universitário e acompanhados pela Equipe de Cuidados com a Pele, além de analisar características como sexo, idade, local anatômico e classificação das lesões. Metodologia: estudo retrospectivo e descritivo com abordagem quantitativa, baseado em registros eletrônicos sendo foram tabuladas em planilhas do Excel e analisadas por meio de estatística descritiva, por distribuição de frequência absoluta e relativa. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa com Seres Humanos da UFPR sob parecer n. 6.680.884. Resultados: Entre os anos de 2018 a 2022, houveram 78 registros de LPs, das quais 60% (n=47) acometeram crianças do sexo masculino. Destaca-se a concentração de casos na faixa etária de um a sete anos 68% (n=53), sendo a UTI Ped o setor com a maior frequência de LP 53,8% (n=56), seguida da Cirurgia Pediátrica 10,6% (n=11). As regiões anatômicas occipital e sacral foram as mais afetadas, com 27% (n=21) e 18% (n=14), respectivamente. Em relação à classificação das LPs, os estágios um e dois predominaram com 31,17% (n=24) eventos cada. Conclusão: A ocorrência de LPs em pacientes pediátricos evidencia os riscos associados ao contexto hospitalar, especialmente em unidades de terapia intensiva, onde a instabilidade clínica e o uso de dispositivos médicos contribuem significativamente para o desenvolvimento de LP. Nesse contexto, as crianças que demandam cuidados intensivos são as mais susceptíveis, uma vez que a criticidade pode interferir na frequência do reposicionamento, um cuidado fundamental na prevenção de LP.
Aplikasi Pembelajaran Pengenalan Komponen dan Perangkat Jaringan WAN Berbasis AR di SMK N 1 Pleret
Authors: Sokani Riski , Oktavia Hardiyantari
Published: January 2025

Limitations in practical tools for introducing WAN components and devices at SMK Negeri 1 Pleret hinder classroom learning activities. The proposed technological solution involves using Augmented Reality (AR). This research aims to develop and evaluate an AR-based learning application for introducing WAN components and devices. The research method used is Research and Development (R&D) employing the ADDIE model, which includes analysis, design, development, implementation, and evaluation. Evaluation was conducted by media experts, subject matter experts, and small groups. Evaluation results indicate that this application is highly suitable, with media expert ratings at 85.45%, subject matter experts at 84.21%, and small groups at 90.71%, all categorized as highly suitable. Based on N-gain score testing, the application has an effectiveness rating of 72.34%, categorizing it as sufficiently effective. This application is expected to serve as an effective tool for learning about WAN components and devices, and contribute as a reference for further research and development.
Antimicrobial activity of ethanol extracts of Sambucus canadensis, Bidens alba, Ricinus communis and Salvia microphylla against foodborne pathogens
Authors: Vázquez Guadalupe Velázquez , Robles Gabriel Salazar , Soria Verónica Rodríguez , Mioni Laura Contreras , Armendáriz Beatriz Pérez
Published: January 2025

Bacteria that compromise food safety cause serious diseases globally, with a higher recurrence in developing countries. This has underscored the need to explore effective antimicrobial alternatives. This study aimed to evaluate the antimicrobial activity of ethanolic extracts from Sambucus canadensis, Bidens alba, Ricinus communis and Salvia microphylla against Gram-positive and Gram-negative bacteria through both in vitro and in vivo tests. Phytochemical analyses and functional group identification using IR spectroscopy were performed. In vitro testing utilized disk diffusion and microplate techniques, while in vivo testing involved Solanum lycopersicum to assess microbial loads within the maximum allowable limit (MAL) according to the Official Mexican Standard NOM-093-SSA1-1994. Phytochemical and IR analyses confirmed the presence of flavonoids, terpenes, and saponins, all of which are known to possess antimicrobial properties. Overall, all extracts inhibited both Gram-positive and Gram-negative bacteria. Notably, the extracts of S. canadensis and B. alba exhibited the largest zones of inhibition, which were statistically significant (P<0.05) compared to the other extracts and the control. Minimum inhibitory concentration (MIC) values ranged from 68.1 to 1000 µg mL-1, with the Sambucus canadensis extract showing the greatest inhibition against Staphylococcus aureus and Klebsiella pneumoniae at 68.1 and 75.1 µg mL-1, respectively. In vivo tests demonstrated that all extracts reduced the bacterial load of the evaluated strains, except for Salmonella typhimurium. These findings suggest that the evaluated extracts could be a promising alternative for natural antimicrobials against foodborne pathogens that threaten food safety and human health.
PERCEIVED QUALITY, BRAND TRUST, AND PRICE FAIRNESS ON CONSUMER LOYALTY OF SILVERQUEEN CHOCOLATE BRAND IN PEKANBARU CITY
Authors: Suhardjo Suhardjo , Juanedi Achmad Tavip , Renaldo Nicholas , Ramadani Yulita , Yovita Indri , Geovanie Geovanie
Published: January 2025

Tujuan penelitian ini adalah untuk mengetahui pengaruh persepsi kualitas, kepercayaan merek dan kewajaran harga terhadap loyalitas konsumen pada merek coklat Silverqueen pada masyarakat Kota Pekanbaru. Populasi penelitian ini adalah konsumen coklat merek Silverqueen di Kota Pekanbaru yang jumlahnya tidak diketahui secara pasti, dan sampel yang diambil dalam penelitian ini sebanyak 100 responden. Teknik pengambilan sampel menggunakan kuesioner berupa google form. Teknik analisis data menggunakan Statistical Program for Social Science (SPSS 21.0). Hasil penelitian menunjukkan bahwa variabel persepsi kualitas, kepercayaan merek dan kewajaran harga berpengaruh positif dan signifikan terhadap loyalitas konsumen pada coklat silverqueen. Perusahaan diharapkan dapat memberikan masukan agar perusahaan dapat terus meningkatkan kualitas coklat silverqueen dan selalu memberikan yang terbaik kepada para konsumennya sehingga para konsumen akan semakin loyal terhadap merek coklat Silverqueen dan agar perusahaan terus berkembang serta mampu bersaing di era modern saat ini.
 
This research aims to determine the influence of perceived quality, brand trust, and price fairness on consumer loyalty to the Silverqueen chocolate brand in the people of Pekanbaru City. The population of this research is consumers of the silverqueen chocolate brand in Pekanbaru City, the exact number of which is not known, and the sample taken in this research was 100 respondents. The sampling technique uses a questionnaire in the form of a Google form. The data analysis technique uses the Statistical Program for Social Science (SPSS 21.0). The results of the research show that the variables perceived quality, brand trust, and price fairness have a positive and significant effect on consumer loyalty to Silverqueen chocolate. The ompany is expected to provide input so that the company can continue to improve the quality of silverqueen chocolate and always provide the best to its consumers so that consumers will be more loyal to the silverqueen chocolate brand and so that the company continues to grow and be able to compete in the current modern era.
Boa noite, o #JN está no ar:
Authors: Maurer Camila , Praxedes dos Santos Carlos Roberto
Published: January 2025

O presente artigo reflete sobre as reconfigurações do consumo de telejornalismo a partir da experiência de segunda tela e apresenta uma proposta de categorização das publicações provenientes do uso do Twitter como segunda tela durante o horário de veiculação do Jornal Nacional. A análise de 725 tweets agregados pela hashtag #JN resultou na identificação de cinco categorias que permitem delinear algumas percepções sobre o modo como os telespectadores usam a rede social para interagir com os discursos produzidos pelo telejornal.o telejornal.
MARCADORES DA FUNÇÃO RENAL ATRAVÉS DA FILTRAÇÃO GLOMERULAR: UMA REVISÃO BIBLIOGRÁFICA
Authors: Beatriz Gomes dos Reis Nucyla
Published: January 2025

Currently, renal disease is a major public health problem that affects thousands of people in Brazil and worldwide, the kidneys are physiologically dynamic components of the system performing many
functions, including the formation of urine, so it is paramount to early diagnosis the disease. The
glomerular filtration rate is the main indicator of renal function in healthy subjects and patients. In this article the main markers of renal injury are assessed: creatinine, urea, proteinuria, cystatin, microalbuminuria. Early markers of renal damage are important because the glomerular filtration rate is reduced before the onset of symptoms or signs of renal disease are therefore important in the diagnosis of renal injury