bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on Bifurcation Response for Vortex‐Induced Vibration of Top Tension Riser in Shear Flow
Authors: Wang Yuancen , Wu Zhiqiang , Zhang Xiangyun
Published: November 2019

The top tension riser (TTR) is one of the most frequently used equipment in deep‐sea petroleum engineering. At present, the research methods of its vortex‐induced vibration (VIV) are mainly focused on finite element analysis and experiment. The understanding of its various nonlinear mechanical mechanisms would be inadequate via limited numerical or experimental studies rather than nonlinear analysis of its rich dynamics. Based on the Van der Pol wake oscillator model, the nonlinear dynamic model of the TTR subject to shear flow VIV is established. The proposed model includes the fluid‐structure interaction of the TTR under shear flow. Dynamic behavior of the TTR in association with the variation of flow velocity is investigated. The dynamic behavior is simulated by computing the local maximum displacement response via the fifth‐order Galerkin discretization. The Poincare map is then utilized to quantify the dynamic property of TTR under each individual flow velocity, which helps identifying the bifurcation path of the nonlinear system. The time history, phase diagram, FFT spectrum, and envelope diagram about the riser VIV at typical flow velocity in different regions of the bifurcation diagram are then given. It is found that the VIV response of the TTR depicts the Hopf bifurcation phenomena with bistable characteristics. Together with the structural eigen‐analysis and the three‐dimensional spectrum contour, the main dynamic features of the TTR in shear flow are more comprehensively understood. Such understandings may provide new ideas and references for the design and optimization of the riser structural parameters.
Comparison of Corneal Parameters of Children with Diabetes Mellitus and Healthy Children
Authors: Wang Shanshan , Jia Yan , Li Tao , Wang Anken , Gao Lu , Yang Chenhao , Zou Haidong
Published: November 2019

Purpose. To compare differences in central corneal thickness (CCT), corneal curvature, and other corneal measurements of children with diabetes mellitus (DM) and healthy children, and to investigate related factors. Methods. This was a case-control study. From January to February 2018, 50 children with diabetes mellitus were selected as a case group, and 46 healthy children and adolescents without diabetes mellitus were selected as a control group. Corneal topography and CCT were analyzed using a corneal topography measuring apparatus and biometrics (IOL Master). In the diabetic group, we analyzed whether age, course of disease, sex, glycosylated hemoglobin, triglyceride level, total cholesterol, body mass index (BMI), parental BMI, birth history, feeding history, pregnancy, or puerperal history were related to corneal morphology. Results. There was a significant difference in CCT between groups, but no significant differences were found in corneal diameter, corneal curvature R1 or R2, or corneal topography. Central corneal thickness was not correlated with other clinical factors in the diabetes group. Conclusion. Early screening and close follow-up of keratopathy in children with diabetes are imperative.
Relationship between Size of the Foveal Avascular Zone and Carbohydrate Metabolic Disorders during Pregnancy
Authors: Sugimoto Masahiko , Wakamatsu Yasuko , Miyata Ryohei , Matsubara Hisashi , Kondo Mineo , Kamimoto Yuki , Ikeda Tomoaki
Published: November 2019

Aim. To determine whether the area of the foveal avascular zone (FAZ), as a morphological indicator of the microcirculation of the perifoveal capillary network, changes in the carbohydrate metabolism disorders during pregnancy (the gestational age of patients with gestational diabetes mellitus (GDM) and preexisting diabetes (PexD)). Methods. Ten normal individuals and 41 eyes of 41 patients, 28 with GDM and 13 with PexD, were studied. A 3 × 3 mm area of the FAZ of the superficial capillary plexus layer (SCP) and the deep capillary plexus layer (DCP) was determined by optical coherence tomography angiography (OCTA; RS-3000 Advance, NIDEK). The significance of the correlation between the size of the FAZ and the weeks of pregnancy was determined. Results. The area of the FAZ of the SCP was 0.38 ± 0.11 mm2 (normal eyes), 0.41 ± 0.16 mm2 (GDM), and 0.43 ± 0.10 mm2 (PexD). The area of the FAZ of the DCP was 0.78 ± 0.23 mm2 (normal eyes), 0.69 ± 0.16 mm2 (GDM), and 0.79 ± 0.25 mm2 (PexD). No significant difference in the FAZ sizes was observed between the groups. The average number of weeks of pregnancy was 24.1 ± 8.2 weeks in the eyes with GDM and 23.3 ± 11.4 weeks in the eyes with PexD (P>0.05). Significant correlations were found between the size of the FAZ of the SCP and the number of weeks (r = 0.37, P=0.04 for GDM, and r = 0.49, P=0.04 for PexD, Spearman’s rank-order correlation coefficient). Conclusions. For GDM and PexD under established glycemic control, the area of the FAZ is not affected, but vascular changes occurred at the early phase of pregnancy.
Hook Plate Technique for Bony Mallet Thumb
Authors: Mukasa Fumihiro , Tomita Yoshimasa , Hirasawa Hideyuki , Kaneko Kazuo
Published: November 2019

Bony mallet is a common sport injury, but bony mallet thumb is rarely encountered. We performed open reduction and fixation of bony mallet thumb using a hook plate procedure on a 27-year-old man under general anesthesia. The patient began working one day after surgery. Six months postoperatively, the patient had excellent dexterity according to Crawford’s evaluation criteria and no difficulties at work or playing softball. Tension band fixation, compression pins, and the extension block technique are commonly used to manage bony mallet. Despite the anatomical reduction, rigid fixation, and early resumption of motion skills offered by the hook plate technique, to our knowledge, no previous reports of its application to bony mallet thumb were found. In this case, the hook plate technique was chosen and made an early return to work possible and brought about a successful result.
Surface Treatment on Nickel Oxide to Enhance the Efficiency of Inverted Perovskite Solar Cells
Authors: Wang Kaijie , Tian Ye , Jiang Heng , Chen Meng , Xu Shuangyan
Published: November 2019

The organic-inorganic hybrid perovskites such as CH3NH3PbI3 have been considered as one of the most promising candidates for the next-generation photovoltaic materials due to its high absorption coefficient, low exciton binding energy, and long diffusion length. Herein, we have chosen NiOx as the hole transport material because metal oxides exhibit robust properties in air. We synthesized the NiOx film by a common sol-gel method. It is found that high-temperature annealing (500°C) is required to ensure the perovskite solar cell (PSC) with an efficiency over 15%. Low-temperature annealing (100°C) cannot convert the precursor materials to fully covered NiOx film, while the PSC based on mediate-temperature annealing (300°C) NiOx has larger resistance and thus lower efficiency. Fortunately, we have found that UV-ozone treatment on the NiOx film can reduce the resistance of the device based on 300°C annealed NiOx. The champion device can reach 16% efficiency with UV-ozone-treated 300°C annealed NiOx. This work has made it possible to reduce the annealing temperature of the sol-gel NiOx for high-efficiency PSCs, and it is believed that this simple surface treatment can be further employed in other metal oxide-based optoelectronic devices.
Proteome Profiling of Membrane-Free Stem Cell Components by Nano-LS/MS Analysis and Its Anti-Inflammatory Activity
Authors: Venkatarame Gowda Saralamma Venu , Vetrivel Preethi , Kim Seong Min , Ha Sang Eun , Lee Ho Jeong , Lee Sang Joon , Kim Young Sil , Pak Jung Eun , Lee Hye Jin , Heo Jeong Doo , Kim Gon Sup
Published: November 2019

The use of adipose-derived stem cells (ADSCs) to enhance wound healing and tissue regeneration is progressively being accepted. Proteomic profiling of cultured ADSCs by mass spectrometry (MS) is a valuable tool to determine the identity of the proteins involved in multiple pathways, which make these ADSCs unique. In the current study, Nano-LC-MS/MS analysis was implemented on the membrane-free stem cell component (MFSCC), and the MS analysis revealed the presence of 252 proteins, that are involved in several biological functions, like metabolic process, biological regulation, developmental process, cell proliferation, and many more. Furthermore, bioinformatic analyses of the identified proteins in MFSCC found them to be involved in versatile pathways, like integrin pathway and wound healing response-related pathways. In addition, we also investigated the anti-inflammatory effects of MFSCC on lipopolysaccharide (LPS) stimulated mouse macrophage (RAW264.7) cells. The cell cytotoxicity of MFSCC was measured using MTT and LDH assays, the production of nitric oxide (NO) was measured by the Griess assay, and the protein expression levels of inducible nitric oxide (iNOS) and cyclooxygenase (COX-2) were examined by western blot analysis. The results showed that MFSCC concentrations ranging from 0.1 to 3 μg/mL did not show any significant cytotoxicity in LPS-induced RAW264.7 cells. Treatment with MFSCC of LPS-stimulated RAW264.7 cells significantly suppressed the production of NO and the expression of iNOS and COX-2 proteins related to inflammation. The present findings lead to a better understanding of the therapeutic potential of MFSCC and strongly promote it for the future clinical development of novel non-cell-based stem cell therapeutics.
Discovering Vulnerabilities in COTS IoT Devices through Blackbox Fuzzing Web Management Interface
Authors: Wang Dong , Zhang Xiaosong , Chen Ting , Li Jingwei
Published: November 2019

A novel approach for discovering vulnerability in commercial off-the-shelf (COTS) IoT devices is proposed in this paper, which will revolutionize the area. Unlike previous work, the web management interface in IoT was used to detect vulnerabilities by leveraging fuzzing technology. To validate and evaluate this scheme, a tool named WMIFuzzer was designed and implemented. There were also two challenges: (1) due to the diversity of web interface implementations, there were no existing seed messages for fuzzing this interface and it was inefficient while taking random messages to launch the fuzzing and (2) because of the highly structured seed message, fuzzing with byte-level mutation could conduce to be rejected by the device at an early stage. To address these challenges, a brute-force UI automation was designed to drive the web interface to generate initial seed messages automatically, as well as a weighted message parse tree (WMPT) was proposed to guide the mutation to generate mostly structure-valid messages. The extensive experimental results show that WMIFuzzer could achieve expected result while 10 vulnerabilities including 6 zero-days in 7 COTS IoT devices were discovered.
Endoscopic Stenting in Hilar Cholangiocarcinoma: When, How, and How Much to Drain?
Authors: Tringali Andrea , Boškoski Ivo , Costamagna Guido
Published: November 2019

Hilar cholangiocarcinoma (HCCA) involves a complex anatomical region where bile ducts, arteries, and veins create a complex network. HCCA can lead to biliary strictures at the main hepatic confluence, involving the right and left radicles. Endoscopic drainage of jaundiced patients with HCCA is challenging and carries a high risk of infective complications. HCCA needs a careful multidisciplinary evaluation to assess the indication and purposes (preoperative/palliative) of the biliary drainage. Biliary drainage in HCCA needs to be planned by magnetic resonance cholangiography in order to study the biliary anatomy and perform a target drainage of the intrahepatic ducts above the malignant hilar stricture; all the opacified intrahepatic ducts above the hilar stricture must be drained to reduce septic complications. Drainage of >50% of the liver volume is important to obtain bilirubin reduction and less complications, but atrophic liver segments (identified by CT scan) do not require drainage due to the increased risk of cholangitis. When preoperative biliary drainage is planned, plastic stents must be inserted. Self-expandable metal stents are indicated for palliative purposes and should be placed only when a complete liver drainage is possible; only uncovered metal stents are indicated to drain malignant hilar strictures to avoid side-branch occlusion.
Effects of Training for Finger Perception on Functional Recovery of Hemiplegic Upper Limbs in Acute Stroke Patients
Authors: Umeki Naho , Murata Jun , Higashijima Misako
Published: November 2019

Background. Stroke causes severe disability, including motor and sensory impairments. We hypothesized that upper limb functional recovery after stroke may be augmented by combining treatments for motor and sensory functions. In order to examine this hypothesis, we conducted a controlled trial on rehabilitation for sensory function to the plegic hand. Methods. The sensory training program consisted of several types of discrimination tasks performed under blind conditions. The sensory training program was performed for 20 min per day, 5 days a week. An experimental group of 31 patients followed this sensory program, while a control group of 25 patients underwent standard rehabilitation. The efficacy of the intervention was evaluated by the tactile-pressure threshold, handgrip strength, and the completion time of manipulating objects. A two-way repeated measures analysis of variance was used to assess interactions between group and time. Moreover, to provide a meaningful analysis for comparisons, effect sizes were calculated using Cohen’s d. Results. The mean change in the tactile pressure threshold was significantly larger in the experimental group than in the control group (p<0.05, d=0.59). Moreover, the completion times to manipulate a middle-sized ball (d=0.53) and small ball (d=0.80) and a small metal disc (d=0.81) in the experimental group were significantly different from those in the control group (p<0.05). Conclusion. The present results suggest that the sensory training program to enhance finger discrimination ability contributes to improvements in not only sensory function but also manual function in stroke patients. The trial is registered with the UMIN Clinical Trials Registry (UMIN000032025).
In-Depth Characterization of Mass Spectrometry-Based Proteomic Profiles Revealed Novel Signature Proteins Associated with Liver Metastatic Colorectal Cancers
Authors: Ku Xin , Xu Yan , Cai Chunlin , Yang Yili , Cui Long , Yan Wei
Published: November 2019

Liver metastasis is the most common form of metastatic colorectal cancers during the course of the disease. The global change in protein abundance in liver metastatic colorectal cancers and its role in metastasis establishment have not been comprehensively analyzed. In the present study, fresh-frozen tissue samples including normal colon/localized/liver metastatic CRCs from each recruited patient were analyzed by quantitative proteomics using a multiplexed TMT labeling strategy. Around 5000 protein groups were quantified from all samples. The proteomic profile of localized/metastatic CRCs varied greatly from that of normal colon tissues; differential proteins were mainly from extracellular regions and participate in immune activities, which is crucial for the chronic inflammation signaling pathways in the tumor microenvironment. Further statistical analysis revealed 47 proteins exhibiting statistical significance between localized and metastatic CRCs, of which FILI1P1 and PLG were identified for the first time in proteomic data, which were highly associated with liver metastasis in CRCs.
Cross-Talk between Oxidative Stress and Inflammation in Preeclampsia
Authors: Tenório Marilene Brandão , Ferreira Raphaela Costa , Moura Fabiana Andréa , Bueno Nassib Bezerra , de Oliveira Alane Cabral Menezes , Goulart Marília Oliveira Fonseca
Published: November 2019

The occurrence of hypertensive syndromes during pregnancy leads to high rates of maternal-fetal morbidity and mortality. Amongst them, preeclampsia (PE) is one of the most common. This review aims to describe the relationship between oxidative stress and inflammation in PE, aiming to reinforce its importance in the context of the disease and to discuss perspectives on clinical and nutritional treatment, in this line of research. Despite the still incomplete understanding of the pathophysiology of PE, it is well accepted that there are placental changes in pregnancy, associated with an imbalance between the production of reactive oxygen species and the antioxidant defence system, characterizing the placental oxidative stress that leads to an increase in the production of proinflammatory cytokines. Hence, a generalized inflammatory process occurs, besides the presence of progressive vascular endothelial damage, leading to the dysfunction of the placenta. There is no consensus in the literature on the best strategies for prevention and treatment of the disease, especially for the control of oxidative stress and inflammation. In view of the above, it is evident the important connection between oxidative stress and inflammatory process in the pathogenesis of PE, being that this disease is capable of causing serious implications on both maternal and fetal health. Reports on the use of anti-inflammatory and antioxidant compounds are analysed and still considered controversial. As such, the field is open for new basic and clinical research, aiming the development of innovative therapeutic approaches to prevent and to treat PE.
The Assessment of the Supply of Calcium and Vitamin D in the Diet of Women Regularly Practicing Sport
Authors: Wrzosek Michał , Woźniak Jakub , Kozioł-Kaczorek Dorota , Włodarek Dariusz
Published: November 2019

Introduction. The appropriate intake of calcium and vitamin D in women’s diet is significant for a proper maintenance of the skeletal system. Research Aim. The aim of the research was to assess the calcium and vitamin D supply in a diet among women regularly practicing sport. Methodology. The research was completed by 593 women at the age of 18–50 (median 25) who played sports regularly (at least 2 times a week). To assess the calcium and vitamin D intake, short Food Frequency Questionnaires for calcium and vitamin D (VIDEO-FFQ) were used. The examined group was provided with the questionnaires via social media. To assess intake levels, the authors applied the group-based cutoff point method (calcium norm was EAR 800 mg/day; vitamin D norm was AI 15 μg/day). Results. The median of calcium and vitamin D intake in a diet was 502 mg/day and 5.2 μg/day, respectively (Q25 and Q75 for calcium was 387 mg/day and 627 mg/day, respectively, and for vitamin D was 3.4 μg/day and 8.2 μg/day, respectively). In relation to the EAR norm for calcium and AI norm for vitamin D, 92.0% of the examined participants in a group demonstrated lower than recommended calcium intake levels and 97.3% showed lower than recommended vitamin D intake levels. Calcium and vitamin D supplementation was used by 13.1% (in this subgroup, 11.5% of the examined group members did not need it) and 56.8% of the examined women (in this subgroup, 2.4% of the examined group did not need it), respectively. After including the calcium and vitamin D intake, the supply median for the whole group was 535 mg/day and 28.8 μg/day, respectively (Q25 and Q75 for calcium was 402 mg/day and 671 mg/day, and for vitamin D was 6.3 µg/day and 55.7 μg/day, respectively); 87.5% of the examined participants did not meet the EAR norms for calcium and 42.0% did not meet the AI norm for vitamin D. Among the women supplementing calcium, 58.9% did not reach the reference intake value; however, all women supplementing vitamin D fulfilled the expected nutritional need. Conclusions. It is important to educate women about the necessity to provide the body with proper calcium and vitamin D intake levels in a diet in order to avoid health problems resulting from the deficit of the nutrients.
Psychotropic Medication Use and Postmenopausal Breast Cancer Risk
Authors: George Anna , Sturgeon Susan R. , Hankinson Susan E. , Shadyab Aladdin H. , Wallace Robert B. , Reeves Katherine W.
Published: November 2019

Background:

Prior studies evaluating psychotropic medications in relation to breast cancer risk are inconsistent and have not separately evaluated invasive and in situ disease.

Methods:

We estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association of psychotropic medication use (any, typical antipsychotics, atypical antipsychotics, and lithium) with invasive and in situ breast cancer risk among Women's Health Initiative participants (N = 155,737).

Results:

Prevalence of psychotropic medication use was low (n = 642; 0.4%). During an average 14.8 (SD, 6.5) years of follow-up, 10,067 invasive and 2,285 in situ breast tissues were diagnosed. Any psychotropic medication use was not associated with invasive breast cancer risk compared with nonusers (HR, 0.82; 95% CI, 0.57–1.18). In situ breast cancer risk was higher among “typical” antipsychotic medication users compared with nonusers (HR, 2.05; 95% CI, 0.97–4.30).

Conclusions:

These findings do not support an association of psychotropic medication use with invasive breast cancer risk. The possible elevation in in situ breast cancer risk associated with “typical” antipsychotics could not be explained by differences in screening mammography utilization and merits further study.

Impact:

Our findings contribute to knowledge of the safety profile of psychotropic medications and may be useful to clinicians and patients considering use of these medications.
Asepsis in Operative Dentistry and Endodontics
Authors: Sriraman Priyanka , Neelakantan Prasanna
Published: November 2019

Operative (Conservative) dentistry and endodontics are specialties of dentistry where the operator is exposed to various infectious agents either via contact with infected tissues, fluids or aerosol. The potential for cross infection to happen at the dental office is great and every dentist must have a thorough knowledge of the concepts of sterilization and disinfection. Disposables should be used wherever possible. Furthermore, the water supply to the dental chair units and water outlets can house biofilms of microbes and should be considered as possible sources of infection. This review discusses the importance of following strict aseptic protocols from the perspective of operative dentistry and endodontics.
Firearms: Ownership, Laws & and The Case for Community Mobilization
Authors: Haider Muhiuddin , Frank Jared
Published: November 2019

The United States (U.S.) currently ranks number one in the world in both the quantity of privately owned guns and the rate of private gun ownership. These privately owned firearms, which include rifles, shotguns and handguns, are predominantly owned by middle-aged, 35-54, white men, but the gaps have been steadily closing over the years, especially depending on the type of firearm, in all areas including gender, age, race, education level, political affiliation and geographic location. Gun violence is a leading cause of injury death in the U.S. In examining gun violence and potentially reducing its incidence, this article reviews gun ownership, access and utilization in the U.S., outcomes of gun violence, and the impact of community involvement in reducing gun violence. Specific areas of focus include the current state of background checks, with a focus on mental illness, and the role of medical professionals in guiding gun policy development. Gun violence continues to negatively impact the safety of individuals, families and communities. This article will emphasize the importance of social mobilization in enacting meaningful changes in gun policy and the development of relationships among healthcare professionals, social workers, and community members so as to further reduce and/or prevent gun violence.
Breakfast Skipping and Obesity Risk among Urban Adults in Bangladesh
Authors: Goon Shatabdi , Islam Md. Saiful
Published: November 2019

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Positive association between skipping breakfast and overweight and obesity is globally observed regardless of cultural diversity among countries. A cross-sectional descriptive study was performed on a total of 426 urban adults, who were randomly selected in a nutrition counseling center of Dhaka city, Bangladesh. The objective of this study was determining the association between breakfast skipping and obesity risk in urban adults of Bangladesh. Results indicated that approximately 35.2% of the sample skipped breakfast. Gender was the only statistically significant sociodemographic variable, with females skipping at two times the rate of males (OR 95% CI: 1.9; 1.3-2.9). Obesity was detected among 39.5% of breakfast skippers and they showed significantly high prevalence (X2=30.15, p<0.05). Skippers were significantly more likely being obese (OR 3.5; 95% CI 2.2-5.5) and obesity was more prevalent in female skippers (X2=8.7, p<0.05), with three times more compared to male skippers (OR 95% CI: 2.8; 1.4-5.9). Breakfast skipping is highly prevalent among urban adult population with significant association of obesity in Bangladesh. Health promotion strategies should be used to encourage all adults to eat breakfast regularly.

 
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Association Between Cytomegalovirus Infection and Bad Obstetric Outcomes in Women from Kirkuk
Authors: Majeed Hassan Hala Mohamed , Alsamarai Abdulghani Mohamed , Aljumaili Zainab Khalil , Alobaidi Amina Hamed , Alsalihi Ferah Ghali
Published: November 2019

The human cytomegalovirus (CMV) is one of the common viral infections worldwide that represent a major causes of congenital infections. To determine the seroprevalence of CMV in women with bad obstetric history and sociodemographic characteristics that may influence the seropositivity, a case control descriptive prospective study  was conducted in Kirkuk, Iraq. A 838 women with age range from 14 to 48 were included in the study. Of the total, 547 women were with bad obstetric history(BOH) and 291 women with normal previous pregnancy as control group. All the serum samples collected from the study and control groups were tested for CMV IgM and IgG antibodies by ELISA kits. CMV IgM seroprevalence was higher in women with BOH. CMV IgG seroprevalence was with no significant  difference between BOH and control. CMV IgG seroprevalence significantly influenced by age, education, smoking, and family size. However, CMV IgM seroprevalence significantly associated with pregnancy, residence, and animal exposure. Odd ratio confirmed the association between CMV IgG and age, crowding index, residence, smoking, and number of abortion in women with BOH.  In addition, current CMV infection significantly associated with residence in women with BOH.
The Determinants and Subsequent Effect of Self-Rated Health Status on Survival among Elderly Americans
Authors: Han Guangming
Published: November 2019

The main aim of this study is to explore the patterns, determinants and subsequent mortality prediction of change in self-rated health in the elderly American population. To achieve this purpose, we constructed logistic regression models and Cox proportional hazard regression models with the complex survey dataset from the National Second Longitudinal Study of Aging (LSOA II) to calculate the odds ratios (OR)/ hazard ratios (HR) and confidence intervals (CI) of risk factors. Our results show that chronic disease condition and difficulty in daily activities are the main reasons for change in self-rated health status. Furthermore, change in self-rated health has significant impact on survival function in the elderly populations. When change in self-rated health status was considered, self-rated health was a stronger and more flexible predictor of mortality for elderly populations. These findings will provide important information to establish effective strategies for prolonging lifespan by improving self-rated health status for elderly populations.
Student’s Perception and Attitudes toward Public Health Profession and National Competency Examination
Authors: Munira Lafi , Handayani Lina
Published: November 2019

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 One form of quality assurance is convening public health’s national competencies examination in academic phase which is conducted before students graduate from university. The purpose of this study was to determine students’s perceptions and attitudes about public health’s profession and national competencies examination. The design of this study was descriptive qualitative employed case study approach. Focus group discussion was used to collect data. Data were analyzed by content analysis. Students felt less confident about their identity profession so that requires motivation by lecturer. Students expressed the need to improve public health graduates’s competencies since academic phase. National competencies examination is important to do as a solution to guarantee the graduates’s quality. Implementation of the competencies test is need to consider aspects of management and technical readiness.  National competencies examination is a tool that could proves the identity of public health graduates’s competencies. Everyone with a public health background should know that there will be a competency test then they should have an adequate preparation.
Do Males and Females Differ in Terms of Their KAP Regarding Halal Pharmaceuticals?
Authors: Sadeeqa Saleha , Sarriff Azmi
Published: November 2019

There is an increasing awareness amongst Muslim consumers to avoid all items containing  non-Halal ingredients including medications. Male and female are different both biologically and psychologically, it therefore, needed for a study to compare KAP of males and females regarding  Halal pharmaceuticals. Methods:This was a cross-sectional study using a structured , self-administered questionnaires to compare the knowledge, attitude & perception regarding Halal pharmaceuticals, among males and females in Penang state of Malaysia. Results revealed that there is no significance difference in the knowledge, attitude and perception of males and females. This is concluded that males and females are equally aware and have same attitude and perception regarding Halal pharmaceuticals. P value of .05 or less was taken as statistically significant.
Mood Change of English, French and Chinese Immigrants in Ottawa-Gatineau Region, Canada
Authors: Tang Ning , MacDougall Colin
Published: November 2019

This multicultural study aimed at examining moodchange of English, French and Chinese speaking immigrants in Ottawa-Gatineau Region, Canada, and identifying demographic factors that impact the change. 810 immigrants of English, French and Chinese speaking sub-groupswere recruited by purposive-sampling. Using self-reports, respondents answered questions regarding moodchange (moodstatus change and mood belief change) and demography in Multicultural Lifestyle Change Questionnaire of English, French or Chinese version. Data were analyzed statistically for the different immigrant sub-groups. Immigrants of different gender, language and category sub-groups exhibited different Mood Change Rates, Mood Improving Rates,Mood Declining Rates and MoodBelief Change Rates. There was no statistical difference between the ratesof immigrant sub-groups.Mood Change (MoodStatus Change + MoodBelief Change) was correlated positively with Mother Tongue and negatively with Speaking Languages. Mood Status  Change was negatively correlated with Marital Status and Highest Level of Education. Mother Tongue, Speaking Languages and Highest Level of Education significantly impacted MoodChange (Mood Status Change + Mood Belief Change). Marital Status and Highest Level of Education significantly influenced Mood Status Change. Immigrants of different sub-groups in Canada experienceddifferentmoodchanges. Marital Status and Highest Level of Educationwerethe main factors impacting Mood Status Change. Mother Tongue and Speaking Languages werethe principal factors influencing Mood Belief Change. Culture was an important factor contributing Mood Change. Acculturation could impact Mood Status Change and Mood Belief Change. Data of immigrant mood change can provide evidence for health policy-making and policy-revising in Canada.
Antioxidant Activity of Some Selected East Borneo Plants
Authors: Ahmad Islamudin , Sulistiarini Risky , Rijai Laode
Published: November 2019

The native plants of East Borneo the Costus specious (Koening) J.E. Smith stem, Lagerstroema spesiosa Pers leaf, Cerbera mangans L leaf, Vitis trifolia L fruit., Scurrula atropurpurea (Blume) Danser root, Brucea javanica (L.) Merr. leaf, Lygodium microphyllum, Bidens Chinensis Willd., Sonneratia caseolaris L. peel, Sonneratia caseolaris L. stem is almost under-explored for their potensial benefits. They were extracted by the solvents of increasing polarity (n-hexane, ethyl acetate, and n-butanol) were tested for their free radical activity against DPPH (2,2-diphenyl-1-picrylhydrazyl). The ethyl acetate extract of Costus spesiosus (Koening) J. E. Smith antioxidant were screnned concentration of 68 ppm, similarly athyl acetate extract of Vitis trivolia L., showed antioxidant activity at 64,30 ppm. As the ethyl acetate extract of Scurrulla atropurpurea (Blume), Brucea javanica (L.) Merr, Lygodium microphyllum and Sonneratia caseolaris L. stem, showed antioxidant activity at 273,52 ppm, 91,12 ppm, 17,39 ppm and 7,03 ppm. N-butanol extract of Lagerstroema spesiosa Pers, Cerbera mangans L, Bidens chinensis Willd, and Sonneratia caseolaris L. peel showed 8,37 ppm, 128,59 ppm, 18,17 ppm and 54,29 ppm antioxidant activity using DPPH model systems. Owing to the property, the studies can be further extended to exploit them for their possible application for preservation of food products as well as their use as health supplements.
Independency Models of Nursing self-care for Ischemic Stroke Patient
Authors: Mendrofa Fery Agusman Motuho , Wahyuni Chatarina U. , Nursalam Nursalam , Machfoed Hasan , Kuntoro Kuntoro , Notobroto Hari Basuki , Hargono Rachmad , Widjonarko Bagus
Published: November 2019

Stroke injury such as physical and psychological disorders was required assistance such as the community, nursing professional and family. Family and social factors play an important role in independence strokes such as support family members provide encouragement for self care.The objective of aim the study wasto assess indicator of self care and model family support related self care. A cross-sectional survey research design was used. Data was collected with interviews by home visited method. Data were analyzed with confirmatory analysis for determined of validity and reliability indicator, models analyzed by SEM (Structural Equation Model).Family support such as information, instrumental, reward and emotion were valid indicator for family support. Self care indicators such as eat, bath, titivate, dress, defecating, urination and transfer to building of self-care. Indicators of eating, bathing, titivate, dress, defecate, urination, and transfer is an indicator for self care. It could be concluded that eating, bathing, ornate, dress, and the transfer is valid and reliable. Model showed that self-care needs were improved of self-carepatients with through family support.
Health Risk of Obesity in Native American Adolescents
Authors: Knisley Benjamin David , Crosby Grace , Barth Margaret , Carothers Linn
Published: November 2019

Recent reports demonstrate the need to improve methods for identifying obesity among adolescent minority populations, especially among Native American adolescents. Our study examined several anthropometric measures to see which one was the best indicator of obesity for Native American adolescents. We compared our data with that provided by the Centers for Disease Control and Prevention (CDC), and the national Health and Nutrition Examination Surveys (NHANESIII). We examined which measures differed significantly from the NHANESIII, and which were most effective for measuring obesity in Native American adolescents. Our study population represented a cross-sectional, epidemiological population (n=183) of Native American students (ages 14-18) from diverse tribal backgrounds at an urban residential high school. We obtained baseline anthropometric measurements of height, weight, waist, triceps skin-fold, and calf skin-fold measures from the Native American students and compared this information with reference data to assess weight classification by body mass indices (BMI) for our population. Under the conditions of our study, we found the calf skin-fold measure to be the best indicator of normal weight in male Native American adolescents, and the triceps skin-fold measure to be the best indicator of obesity in male Native American adolescents. The assessment of health risk by anthropometric measures we obtained appears appropriate for predicting obesity and developing effective interventions for Native American adolescents in general. Correlations between anthropometric measures and obesity in our study population may prove of significant interest for monitoring obesity prevention initiatives for Native American adolescents.
Pharmaceutical Care Training Increases the Ability Pharmacists to Reduce the Incidence of Medication Error
Authors: Akrom Akrom , Budiyono Budiyono , Supadmi Woro
Published: November 2019

The objective of the study was to know the potential incidence of medication errors before and after the training of pharmaceutical care in the Outpatient Pharmacy Unit of general privat hospital in rural area of Yogyakarta. The observational studi used to describe the potential medication errors in prescribing phase and dispensing phase and to determine its completion. This research was conducted prior to the training of pharmaceutical care that is in May and after the training of pharmaceutical care that was in June 2014 at the Outpatient Unit of general privat hospital in rural area Yogyakarta. The data was taken from a book review of prescriptions in outpatient units for the month. The results showed that the number of potential medication errors before the training of pharmaceutical care in prescribing phase (prescribing errors) found 17 cases or 0.21% and the dispensing phase (dispensing error) as many as 36 cases or 0.45%. While the potential for medication errors after the training phase of pharmaceutical care in prescribing phase (prescribing error) is found as many as 115 cases or 1.45% and the dispensing phase (dispensing error) is found as many as 165 cases or 2.10%.
The Correlation between Smoking Status and BMI with The Complaints of Musculoskeletal Disorders on Palm Farmers
Authors: Oktaviannoor Husda , Helmi Zairin Noor , Setyaningrum Ratna
Published: November 2019

According a study by Research Centre and Health Ecology Development Ministry of Health in 2004, palm farmers are one of a group worker that suffers complaint musculoskeletal disorder. This research to determine the correlation between the smoking status and BMI with complaints of musculoskeletal disorders (MSDS) of palm farmers in PT. X. The method are analytic observational with the cross-sectional approach. Instruments such as questionnaires, mikrotoise, scales underfoot, check the NBM, and VAS. Research technique is use purposive sampling. Research sample of 40 respondents. Results showed 32.5% light smokers, 45% moderate smokers, and 15% of heavy smokers, 17.5% weight and 2.5% obese, and 60% had complaints of MSDs. Spearman test results, it is known there is a correlation between the smoking status with complaints of MSDs (p=0.037), there was no significant correlation between BMI with complaints of MSDs (p=0.272). It can be concluded that there is a correlation between the smoking status with MSDs complaints, but there is no correlation between the BMI with the MSDs complaints. This research is expected to be input for the company to conduct training exercises ergonomics and providing information about the importance of maintaining the health of tobacco consumption.
High Glucose, but Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells
Authors: Jenie Ikhlas Muhammad , Mulyono Budi , Aswin Soedjono , Soejono Sri Kadarsih
Published: November 2019

Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases. Platelet hyperreactivity has been frequently found in patient with diabetes mellitus. To examine whether testosterone and high glucose modify platelet aggregation through endothelial cells, we did an in vitro study using endothelial cells culture from human umbilical vein (HUVEC). Treatments were performed in HUVEC sub culture as either normoglucose (5.6 mM) or high glucose (22.4 mM) medium, with or without testosterone (0, 1, 10, 100 nM), for 24 hours. HUVEC were trypsinized, resuspended, and then incubated with platelet rich plasma from healthy male donors with ratio 1:104 for 3 minutes. Platelet aggregation measured by turbidimetry methode. This study showed that testosterone did not significantly influence platelet aggregation through endothelial cells in normoglucose (p = 0.144) or high glucose (p = 0.916) medium. There was no main effect of testosterone (p = 0.73) as well as no interaction between testosterone and glucose (p = 0.69), but there was a main effect of glucose (p = 0.004), to platelet aggregation through endothelial cells. In conclusion, high glucose, but not testosterone, inhibits platelet aggregation mediated by endothelial cells.
Peer-reviewed Public Health Journals
Authors: Al-Aboud Nora Mohammed , Al Aboud Khalid , Qurashi Ahmad Al
Published: November 2019

Peer-reviewed Public Health journals are essential media for the workers in the public health field. There are already many periodicals published in the public health domain and still many new ones are being added. Journalism in public health is facing many changes and challenges. Technologies and smart phones applications in particular affected the pattern of publication and readership of these journals. This report shed some light on the current peer-reviewed periodicals in the public health.
Gabapentin and Amitriptilin Treatment toward Living Quality of Post Ischemic Stroke Patients with Neurophaty Pain
Authors: Utami Pinasti , Ikawati Zulies , Setyaningsih Setyaningsih
Published: November 2019

Stroke becomes a significant problem for developing countries. In Indonesia the data show its incidences 234 per 100.000 people, and around 2 - 8 % stroke patients experiencing cerebrovascular session will get neurophaty pain. It happens because of sensoric deviation after stroke, so the brain does not completely send information to the body correctly. Patients experiencing neurophaty pain are able to face decreasing living quality as the effect of long term painful disturbance. Therefore, it is important to maintain the patients’ living quality. The aim of the study is to investigate the comparison of using gabapentin and amitriptilin toward living quality of ischemic stroke patients with neurophaty pain in the hospitals in Jogja. The method used in this study was quasi experimental with consequtive sampling. The study was conducted on 22nd of April-31st of Juli 2013 by involving 23 patients in gabapentin group and 18 patientsin amitriptilin group that would be evaluated during 1 month. Living quality was assessed by Brief Pain Inventory (BPI) in week 0 and week 4. The result of the study showed that the use of gabapentin and amitriptilin in 4 weeks showed the increase of living quality represented by decreasing the score based on BPI questioner 1.67±0.78 and 1.37±0.80 with p-value>0.05 meaning that there was no significant difference. It can be concluded the comparison of using gabapentin and amitriptilin in post ischemic stroke patient with neuropathy pain not significantly increase the quality of in the hospitals in Jogja.
Students’ Perception on Interprofessional Education
Authors: Orbayinah Salmah , Utami Laksmi Putri
Published: November 2019

Unawareness of the roles and competencies of other health professions has led to many medical and medication errors in the treatment of patients in the hospital. It is considered important to give Interprofessional Education (IPE) to students at pre-clinic and clinical stage in order to have a good understanding about roles of other health professionas. IPE is an interprofessional collaborative learning to support promotive, preventive, curative, rehabilitative and other approches related to health aspect. Perception is among the most important and highly needed skill in the implementation of IPE. This research aimed to determine the effect of IPE learning toward the perception among the students in Faculty of Medicine and Health Science of Universitas Muhammadiyah Yogyakarta (FMHS UMY). This is an observational study adopting a cross sectional design. The sample of students was collected through purposive sampling technique. A number of 94 students met the inclusion criteria, comprised of 21 students of Medical Profession Education, 25 of Dentistry Profession Education, 25 of Nursing Profession Education and 21 Undergraduate students of Pharmacy. Samples were given questionnaire of Interdiciplinary Education Perception Scale. Comparative test was done by Kruskall-Wallis test. From 94 students of FMHS, 75.5% had good perception toward IPE. No significant differences appeared in perception (p=0.285) among the students of FMHS UMY. The Interprofessional Education (IPE) had significant effects toward the perception among the students of FMHS UMY.
Stroke Treatment Cost Analysis for Consideration on Health Cost Determination Using INA- CBGs at Jogja Hospital
Authors: Hadning Ingenida , Ikawati Zullies , Andayani Tri Murti
Published: November 2019

Indonesian Case Based Groups (INA-CBGs) implementation on hospital financing for stroke patient using Jaminan Kesehatan Masyarakat (Jamkesmas) at 3rd class hospitalization requires therapy plan management and cost analysis because stroke is a leading cause of death worldwide and need high treatment cost. It is purposed to skimp the hospital expenditure and avoid deficit suffering. The study objectives was to determine the suitability cost between real stroke treatment cost and health financing based on INA-CBGs, and to determine the highest cost component on stroke treatment at Jogja hospital. This cross sectional observational study used retrospective sampling method. The subjects were taken from all stroke patient population using Jamkesmas insurance at Jogja Hospital, were hospitalized between January 2011-April 2012 and met the inclusion criteria. The subject was then classified based on INA-CBGs. Patient’s length of stay and costs (direct medical and direct non-medical costs) were defined as study variable. Data was analysed using descriptive analysis and Mann Whitney test. Throuh this study we conclude the average rate of real stroke treatment cost at Jogja Hospital was higher insignificantly than INA-CBGs based cost and the highest treatment cost was on the medicine and medical equipment.