bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS CSR DAN GCG TERHADAP KINERJA KEUANGAN DENGAN ISO STANDAR SEBAGAI VARIABEL INTERVENING (STUDI EMPIRIS PADA PERUSAHAAN YANG LISTING DI LQ45)
Authors: BAJ Widia Wahyuningrum
Published: October 2020

This study aims to test Corporate Social Responsibility and Good Corporate Governance on the company's financial performance, testing the effect of ISO on company performance. This type of research is quantitative research. Through this research the researcher tries to test the financial performance of the company that is listing in LQ 45 which is influenced by Corporate Social Responsibility, Good Corporate Governance, and ISO Standard 14001. The results showed that GCG had a significant effect on Tobins Q, so that it can be interpreted that companies that implement GCG can help companies improve their financial performance. CSR has no significant effect on Tobins Q. It can be interpreted that CSR focuses more on the problems that might arise on the external company and does not have a direct influence on financial performance. GCG has a significant effect on ISO, this can be interpreted when companies that implement GCG and are accompanied by obtaining ISO certification, will be able to help each other in creating good governance for the company. CSR has no significant effect on ISO. It can be interpreted that companies that implement CSR have no influence on the ISO certification that the company has. ISO has an effect on Tobins Q. It can be interpreted that companies that have ISO certification can have a positive effect on the company's financial performance.
PENGARUH PEMBELAJARAN DARING TERHADAP MINAT BELAJAR MAHASISWA PADA MASA PANDEMIK COVID-19
Authors: BAJ Syarifah Hikmah Jamil , BAJ Invony Dwi Aprilisanda
Published: October 2020

Pandemics that hit the world including Indonesia had an impact on all sectors, including the Education sector. This has an impact with the introduction of distance learning with an online learning system. Because of this distance system the lecturer is required to be able to convey the course material well to students. This study aims to determine whether online learning carried out by lecturers at INSTIKA and UPN East Java can increase students' interest in studying the courses they tidake. The sample used in this study were 278 students. The analytical tool used was IBM SPSS Version 21. The results showed that the attitude of internet use, perception, experience, financial condition significantly influenced students' interest in learning. While the ability to learn independently does not have a significant effect on student interest in learning during online lectures.
Motive of Millennial Generation Competency in Public Service Implementation in Sidoarjo District
Authors: EBGC Moch. Ali Mashuri
Published: October 2020

In the organization of the One-Stop Investment and Integrated Services Office of Sidoarjo Regency where there is a cultural clash in the organization, the baby boomer generation has a more rigid behavior in bureaucratic activities and is not following the development of ICT. The millennial generation is very flexible with ICT, is fast paced and wants ease in working in organizations, is bored with routine, and prefers to work behind the scenes. The purpose of this research is to uncover the motive of millennial generation competence in the implementation of electronic-based public services. The research method used is qualitative. Informants are employees of the One Stop Investment and Integrated Services Office of Sidoarjo Regency who fall into the millennial generation category of 8 informants. The results of this study that the motive for developing millennial generation competence in the implementation of electronic-based public services is obtained by millennial generation employees in addition to working to meet their basic daily needs, they want to work according to the rules (standard operational procedures) and the applicable system, achievement motives or rewards, and want to develop soft competence and hard competence to be more professional at work
Board of Knowledge about Budgeting Regional Financing (APBD) in Sidoarjo
Authors: EBGC Santi Rahma Dewi , EBGC Kukuh Sinduwiatmo , EBGC Sarwenda Biduri
Published: October 2020

This study aims to find out how the board's knowledge about the budget in implementing regional financial supervision (APBD). This research was conducted with qualitative methods by presenting elements of questions regarding the board's knowledge of budget and regional financial supervision. Methods of gathering information using interviews and documentation to members of the Sidoarjo Regency council. The results of this study indicate that board members understand the process of determining the budget carried out by the executive, so that they can supervise and control the implementation of the APBD in Sidoarjo Regency. And expect follow-up from the executive on recommendations that have been given by the legislature where so far there has been no follow-up done.
Financial Ratio Analysis of Bank Performance
Authors: Ariesta Vinky Era , Marlina Marlina , Hidayati Siti
Published: October 2020

This study aims to determine the effect of Firm Size proxied with SIZE), Credit Risk proxied by Non Performing Loans (NPL), and Capital Adequacy proxied with Capital Adequacy Ratio (CAR) toward Bank Performance proxied by Return on Asset (ROA). Population in this study are banking companies listed in Indonesia Stock Exchange (IDX) 2015-2017. The technique of determination of the sample using the method of purposive sampling and obtained 27 banking companies with a research period of three years to obtain 81 units of samples. Data analysis was done using Microsoft Excel 2010 and hypothesis testing in this research using Data Panel Regression Analysis with the E-Views 9.0 program and a significance level of 5%. The results of the research shows that (1) Firm Size (SIZE) has a significant positive effect on Bank Performance (ROA), (2) Credit Risk (NPL) has a negative and significant effect on Bank Performance (ROA), (3) Capital Adequacy (CAR) has no effect and significant on Bank Performance (ROA).
Public Trust and Financial Transparency of E-Government Implementation in Bandung City
Authors: EBGC Dini Arwati , EBGC Dini Verdania Latif
Published: October 2020

Indonesia government, at the time, is now trying to implement e-government in each of the Organization. E-government is a technology and information-based system that aims to improve the function of public administration and relations with the public. With e-government, it hoped that information transparency would be created, especially financial information. A transparent system can prevent the misuse of the budget, which affects the high level of corruption. Survey results at the global level show that there are cases of fraud that cause distrust of the government. The study is intended to determine the level of trust of society towards transparency finance in e-government. The research method used is the descriptive method by distributing questionnaires to 200 people of Bandung residents. The results showed that financial transparency in e-government affected people's trust.
Phenomenological Studies of Grounded Participation: Important Contributions to Meaningful Programs?
Authors: Nuswantara Dian Anita
Published: October 2020

Development program should result in resolution for public problems. There is a need to harmonize the longterm program (i.e. RPJMD) with its budget allocation. It found that some regions did not have those synchronized programmed, including Kabupaten Blitar. The spirit of increasing public wealth did not follow with the budget that tends to allocate in routine expenses. In that, this research is encouraged to see how program development practices in Blitar through Musrenbang. The results show that the Musrenbang already covered those kinds of public participation. Because the guidelines already mentioned it in its guiding book. So, they obey it. Unfortunately, when the proposal is submitted to the higher level, i.e. Musrenbang Kabupaten, the program are not inline with a longterm plan. This condition may cause the proposal are rejected or even accepted it would not solve the fundamental problems identified by the government
The Effect of E-Learning Resources on Image and Implications on Trust (Study at Open University in Indonesia)
Authors: Widokarti Joko Rizkie , Ginting Ginta
Published: October 2020

This study aims to examine the effect of e-learning resources on images, the influence of e-learning resources trusts, the influence of images on trusts, and the influence of e-learning resources trusts through images. This research uses quantitative research methods. Time horizon is cross sectional, because it is done at a certain time. The unit of analysis is the Open University with the observation unit being students from the Open University, with a sample of 300. The analytical design used to test hypotheses and determine the relationship between research variables is Structural Equation Modeling (SEM). The results showed that E- learning resources also affect the image of the trust. Image affects trust. The development of trust in E-learning is more dominantly built by images, and images are built by e-learning resources. The results of this study have implications for university management in the development of e-learning that increasing trust needs to be built by efforts to improve image. To develop an image, it is necessary to build adequate e-learning resources that are built with the development of tangible assets and intangible assets
Optimizing the Utilization of GoFood System Application as an Income Enhancement at Rungkut Surabaya MSME
Authors: EBGC Invony Dwi Aprilisanda , EBGC Devy Sylvia Puspitasaria , EBGC Luqita Romaisyah
Published: October 2020

In the digital age, technological developments are moving very fast and changingthe lifestyle of humans in general. The technological system in the Digital Ageattracted the interests of culinary MSME entrepreneurs in Indonesia to do businesswith an online sales system. One of the online food delivery service applications inIndonesia is GoFood, this study aims to find out how SMEs in Surabaya asGoFood partners can increase their income by optimizing the use of the GoFoodapplication. This study uses a qualitative method. Data analysis in this research isdescriptive qualitative. Criteria for selecting informants using purposive samplingtechniques. The interview results state that the GoFood application tends to beeasy to use, but some partners regretted the lack of training which resulted in salesnot meeting expectations. Quality, Quality, Promo Price, and timeliness of foodprocessing to food delivery to consumers is a strategy for GoFood merchantpartners to optimize their sales turnover.
The Influence Factors Interest in Buying on E-commerce
Authors: EBGC Nuruni Ika Kusuma Wardani , EBGC Ignathia Martha Hendrati , EBGC Sishadiyati
Published: October 2020

Technology in Indonesia is currently experiencing rapid advances in informationtechnology and communication, especially internet advancements. In Indonesiaalone, people who use the Internet have increased very rapidly. With the largenumber of people using the internet in Indonesia, there is a trend of onlineshopping through websites or online shop applications. Based on these thoughts, itis interesting to examine whether the perception of ease of transaction and trustaffect buying interest in e-commerce. The population in this study are consumerswho use e-commerce. While the samples taken were 60 respondents. The analysistechnique used is Partial Least Square (PLS). From this research it can be seen thatthe perception of ease of transaction and trust can contribute to e-commercebuying interest.
Analisis Komparatif Kinerja Reksadana Saham & Reksadana Indeks Berdasarkan Metode Sharpe, Treynor, dan Jensen
Authors: Lorencia Maria , Taufiq M.
Published: October 2020

Mutual fund get investors attention cause the risk rate are smaller than the other investment instrument, its because mutual fund are managed by a reliable party on investment called professional management. Different types of mutual funds offer different ranks of risk and return. This study use secondary data and independent sample t-test analysis technique with computer assist program SPSS 13 to compare performance between equity fund that use active management strategies and mutual fund index that use passive management strategies. Test result show that performance between equity fund and mutual fund index measured using sharpe, treynor and jensen methods are don’t have significant performance differences. So investors are free to invest their money on equity fund instrument or mutual fund index, cause its return and risk are similar.
Model Aplikasi Sistem Pembuatan Ticketing Untuk Meningkatkan Pelayanan IT Support Kepada Karyawan
Authors: Sutrisno Sutrisno , Alfeno Sandro , Nurwana Giansah
Published: October 2020

Informasi basis komputer dikenal orang hingga saat ini sebagai alat pengolah data untuk menghasilkan beberapa informasi. PT Agung Poly Nugraha merupakan salah satu perusahaann Manufacturing terkemuka di Indonesia. Pada dasarnya pelayanan pada perusahaan Manufacturing sebagian besar dilakukan oleh sistem. Namun, untuk sistem permintaan IT support masih berjalan manual dengan melakukan permintaan IT Support menggunakan telpon ke divisi IT, kemudian staff IT Support mencatat kembali apa yang sudah dikerjakan dalam sebuah kertas. Tujuan penelitian ini ialah, menganalisa pelayanan ITsupport dan menciptakan sebuah sistem untuk meningkatkan pelayanan ITsupport. Perancangan sistem dalam penelitian ini menggunakan metode observasi, wawancara dan studi pustaka guna menganalisa sistem yang berjalan.Perancangan sistem menggunakan UML.Perangkat lunak yang digunakan dalam perancangan adalah bahasa pemrograman PHP, framework Codeigniter, PHP MYSQL dan aplikasi Visual Studio Code.Aplikasi system ticketing untuk meningkatkan pelayanan IT support diharapkan dapat menyelesaikan permasalahan dalam meningkatkan pelayanan IT support dan penyimpanan riwayat perbaikan yang di kerjakan oleh divisi IT Support. Sistem juga dapat menjadi acuan untuk pengembangan sistem yang sudah berjalan.
Johtamiskoulutus murrosvaiheessa
Authors: Peltonen Matti
Published: October 2020

Artikkelissa tarkastellaan aluksi suomalaisen yhteiskunnan eräitä kehityspiirteitä 1950-luvulta alkaen ja sen jälkeen yritysten ja johtamisen muuttumista pyrkien luomaan niitä koskeva skenaario myös 1980-luvulle. Tarkastelussa päädytään toteamaan johtamistaidollisen koulutuksen olevan murrosvaiheessa, jossa myös aikuiskasvatuksen teoriapohja ja didaktiikka ovat tarpeen pulmien ratkaisemiseksi.
Pedagogiikka, andragogiikka ja kasvatus
Authors: Harva Urpo
Published: October 2020

Artikkelissa analysoidaan andragogiikka ja pedagogiikka -käsitteitä sekä niiden käyttöä. Siinä tehdään myös ero aikuisten opettamisen peruskäsitteiden aikuiskoulutuksen ja aikuiskasvatuksen välille.
Henkilöstökoulutuksen tämän hetken ongelmia
Authors: Virkkunen Jaakko
Published: October 2020

Henkilöstökoulutuksen tärkeimmäksi ongelmaksi nähdään pätevän toimintaa ohjaavan ammattiopetuksen didaktiikkaa koskevan teoreettisen tiedon ja tutkimuksen puuttuminen. Tällöin sattumanvaraisesti valitaan koulutusta koskevat mallit ja teoreettiset näkemykset. Koska henkilöstökoulutukselta vaaditaan yhä suurempaa tehokkuutta, tarvitaan sen suunnittelun pohjaksi teoreettisesti perusteltua didaktisia kokonaisnäkemystä ja entistä laajempaa tieteellisen tiedon soveltamista.
Avoimen korkeakoulun avoimet ongelmat
Authors: Tuomisto Jukka
Published: October 2020

Artikkelissa tarkastellaan kriittisesti Avoimen korkeakoulun toimikunnan mietintöä. Siinä todetaan mm. että avoin korkeakoulu ei ole onnistunut sivistyksellisen tasa-arvoisuuden edistämisessä ja että yliopistojen kansansivistystehtävä on kehittämisessä unohdettu lähes kokonaan. Kirjoittajan mielestä avoin korkeakoulu olisi ensisijaisesti nähtävä osana korkeakoululaitoksen kehittämistä.
Effects of Luminaire Angle and Illumination Topology on Illumination Parameters in Road Lighting
Authors: Cengiz Mehmet Sait
Published: October 2020

In this study, refers to two errors in road lighting. It explains the advantages of the staggered layout of luminaires and the problems associated with the use of luminaires located at an angle to the horizontal line of the road. The errors made by the simulation program were proved quantitatively and suggestions for their solution were presented. The loss of luminance of the road surface when illuminated by luminaires located at an angle to the horizontal has been quantitatively proved. In addition, it was found that with the appropriate choice of the layout of luminaires with road lighting, the step between the poles could be reduced by 9.3 %.
Applicability of a Prismatic Panel to Optimize Window Size and Depth of a South-facing Room for a Better Daylight Performance
Authors: Kose Busra , Kazanasmaz Tuğçe
Published: October 2020

This study examines the performance of attached prismatic panels, which have shading capability, in a side-lit deep plan room to find out the least possible WWR value in relation to room depth satisfying the required daylight availability. The methodology is based on simulating a base model in Relux and testing it with alternative models composed of incrementally defined WWR and room depth values. In accordance with minimum IES requirements, the most satisfying sDA value was found to be 48.54 % in a room of 12 m depth with 67 % WWR. An sDA of 51.59 % and 59.26 % was achieved in a room of 9m depth with 43 % WWR and 6m depth with 30 % WWR, respectively. The least ASE values were obtained with the least WWR alternative of 30 % in all room depths. This study presents a new approach with the consideration of innovative daylight redirecting systems to propose revisions for the requirements mentioned in standards about daylight in buildings but based on conventional fenestration systems.
Study of Operating Modes of a Controllable Lighting System Consisting of a Triac Dimmer and a LED Light Source with a Controllable Driver
Authors: Kondratieva Nadezhda P. , Filatov Dmitry A. , Terentiev Pavel V.
Published: October 2020

The article covers the study of the effect of a dimmer on operation of a light source and elec tromagnetic compatibility of a controllable light ing system. It is found that with reduction of ac tive power P of a light source its luminous flux and bulb heating temperature decrease, the power factor of the lighting system decreases too with increas ing of the total harmonic distortion current factor of the lighting system. The changes are non-linear. Mathematical expressions related to changes of lu minous flux, heating temperature, power factor and total harmonic distortion caused by change of active power of a light source are obtained. A conclusion is made that together with an opportunity to save ener gy and to increase the operating life of the control lable lighting system application of a dimmer leads to reduction of electric power quality and electro magnetic compatibility of this system. The study also demonstrated that changes in supply voltage also affect operation of the controllable lighting system. Reduced supply voltage causes the high est effect on characteristics of the lighting system. Change in the supply voltage strongly affects the lu minous flux and the heating temperature of the light source and the power factor of the lighting system in operating modes at 0.25 of Pnom and 0.5 of Pnom and the total harmonic distortion in operating modes at 0.75 of Pnom and Pnom.
Analytic Representation of Relation between Solar Altitude Angle and Local Time for Calculating Daylight Irradiance and Illuminance of the Earth Surface
Authors: Leonidov Alexander V.
Published: October 2020

The analytic expression which sets relation between the solar altitude angle and local time at a random point of the Earth surface on a random day of a year is obtained. The obtained expression and derived relations allow one to conduct calculations of daylight irradiance and illuminance of the Earth surface in analytic form.
Gas embolism and massive blunt force trauma to sea turtles entrained in hopper dredges in North and South Carolina, USA
Authors: Harms CA , Boylan SM , Stacy BA , Beasley JF , García-Párraga D , Godfrey MH
Published: October 2020

Decompression sickness (DCS) has been described mainly in loggerhead turtles Caretta caretta bycaught in trawls and gillnets. Here we present cases of gas emboli (GE) in 8 green turtles Chelonia mydas and 2 Kemp’s ridleys Lepidochelys kempii entrained in hopper dredges that were working at 8.8-15.2 m depths during shipping channel maintenance or beach renourishment activities. Turtle weights ranged from 2.2 to 6.7 kg. All were found alive with blunt force injuries from passage through the dredge and were taken to rehabilitation facilities. Four green turtles died or were euthanized within 24 h. Six turtles survived. Radiographic or ultrasonographic evidence of GE was detected in 4 turtles, including 3 mortalities. Computed tomography (CT) revealed perirenal and cervical GE in 4 turtles, including 1 mortality. No GE were detected in 2 of the survivors. Upon necropsy, GE were found in mesenteric vessels, the right atrium, and kidneys. Histopathology confirmed that tissues were in a good state of preservation without evidence of bacterial overgrowth or putrefactive gas formation. Death likely resulted primarily from massive tissue trauma from the dredge, but moderate GE could have led to DCS and complicated recovery. The surviving turtles weighed less than those that did not survive. Besides hypothesized stress/exercise-induced circulatory changes of blood through the lungs and pressure reduction of forced surfacing from depth, drastic pressure change within the dredge pipes before and after the pump could contribute to GE. Hopper dredge entrainment is an additional cause of GE and potential DCS in sea turtles.
Locality, time and heterozygosity affect chytrid infection in yellow-bellied toads
Authors: Oswald P , Rodríguez A , Bourke J , Wagner N , de Buhr N , Buschmann H , von Köckritz-Blickwede M , Pröhl H
Published: October 2020

The chytrid fungusBatrachochytrium dendrobatidis(Bd) infects numerous amphibian species worldwide and is suggested to drive population declines and extinction events. We report a study ofBdinfection at the northernmost distribution of the European yellow-bellied toadBombina variegata. A total of 577 individuals from ponds in 16 study sites were sampled for DNA andBdthroughout the breeding season. Microsatellite genotyping revealed 3 genetic clusters for the hostB. variegatawith an overall low genetic diversity. One of the clusters displayed a low microsatellite heterozygosity, a high inbreeding coefficient as well as highBdinfection prevalence and intensities. Multi-model estimates identified site, time of sampling, and heterozygosity to be important predictors of an individual’sBdinfection status, and identified a strong effect of site on individualBdinfection intensity. The study site effects are suggestive of localized infection peaks, and the increase of individualBdinfection probabilities towards the end of the sampling period suggests cumulative infection during the breeding season. This study highlights the need for regular monitoring ofBdinfection variables at multiple localities and times to gain insights intoBddynamics. Due to the detected relationship between individualBdinfection status and heterozygosity, conservation measures should focus on the maintenance of high genetic diversity and connectivity within and among amphibian populations.
Spatio-temporal distribution of spinetail devil ray Mobula mobular in the eastern tropical Atlantic Ocean
Authors: Lezama-Ochoa N , Lopez J , Hall M , Bach P , Abascal F , Murua H
Published: October 2020

The distribution of the spinetail devil ray Mobula mobular in the eastern tropical Atlantic remains poorly known compared to the Pacific and Indian Oceans. We used fishery-dependent data and generalized additive models to examine the environmental characteristics associated with the presence of M. mobular in the eastern Atlantic Ocean. Results revealed that the distribution of M. mobular is significantly associated with seasonal upwelling systems in coastal and pelagic areas. Our model predicted the presence of the species in areas where there is evidence of its occurrence, such as the Angolan upwelling system and the coast of Ghana. In addition, our model predicted new hotspot areas, including locations around the Mauritanian upwelling system, the Guinea coast, offshore Ghana and the south coast of Angola and Brazil, where sample sizes are limited. Those areas, as well as the environmental preferences depicted by the model, provide valuable information about the habitat and ecology of the spinetail devil ray. Future research lines derived from this study, as well as its limitations, are discussed. Furthermore, in light of our results we discuss the improvements that are needed to contribute to the conservation and management of this vulnerable species.
Statistical modelling reveals spatial, temporal, and environmental preferences for white sharks at an oceanic aggregation site
Authors: Becerril-García EE , Martínez-Rincón RO , Galván-Magaña F , Santana-Morales O , Hoyos-Padilla EM
Published: October 2020

Guadalupe Island, Mexico, is one of the most important white shark (Carcharodon carcharias) aggregation sites in the Eastern Pacific. In the waters surrounding Guadalupe Island, cage diving has been carried out since 2001 during August-November; however, there is scarce information regarding the factors associated with this seasonal aggregation. The purpose of this study was to describe the probability of occurrence of white sharks relative to spatial, temporal, and environmental factors in Guadalupe Island. Generalized additive models (GAMs) were used to describe the effect of sea surface temperature, water visibility, tide, moon phase, cloud cover, time of day, and location on white shark occurrence. GAMs were generated from a data set of 6266 sightings of white sharks, classified as immature males, mature males, immature females, and mature females. A sexual segregation related to month was observed, where females arrived after males during late September. GAMs evidenced a segregation of white sharks according to the analysed variables, which is consistent with previous observations in this locality. Environmental preferences for each white shark category are potentially influenced by feeding habits, sexual maturation, and reproduction. This study constitutes a baseline of the effect of the environment on the occurrence of white sharks in Guadalupe Island, which can be used in further studies regarding management and conservation in future climatic and anthropogenic scenarios. Its relevance is related to the understanding of its ecology in oceanic environments and the presence of this threatened species during the ecotourism season.
Estradiol, Obesity and Hypogonadism
Authors: STÁRKA L. , HILL M. , POSPÍŠILOVÁ H. , DUŠKOVÁ M.
Published: October 2020

Obesity increases the incidence of hypogonadism in men, and hypogonadism in turn plays a role in obesity. One of the first mechanisms proposed to explain this was a hypothesis based on the principle that obese men have higher estrogen levels, and that increased estrogens provide feedback to the hypothalamic-pituitary-testicular axis, reducing the secretion of gonadotropins and leading to a decrease of overall testosterone levels. This concept has since been questioned, though never completely disproven. In this study we compared hormone levels in three groups of men with differing BMI levels (between 18-25, 25-29, and 30-39), and found correlations between lowering overall testosterone, SHBG and increased BMI. At the same time, there were no significant changes to levels of free androgens, estradiol or the gonadotropins LH and FSH. These findings are in line with the idea that estrogen production in overweight and obese men with BMI up to 39 kg/m2 does not significantly influence endocrine testicular function.
Midazolam and Its Effect on Vital Signs and Behavior in Children Under Conscious Sedation in Dentistry
Authors: VASAKOVA J. , DUSKOVA J. , LUNACKOVA J. , DRAPALOVA K. , ZUZANKOVA L. , STARKA L. , DUSKOVA M. , BROUKAL Z.
Published: October 2020

Midazolam is a short acting sedative with small number of adverse effects. Administered orally, it is currently the most common form of conscious sedation in children. The objective of this paper is to describe effect of midazolam administered to children during dental treatment on their vital signs, and to monitor changes in children’s behavior. We described values of vital signs and behavior in 418 sedations conducted in 272 children between 1-12 years of age. To achieve the following results, we used data from 272 all first-time sedations. After administration of midazolam arterial blood pressure and blood oxygen saturation decreased by values which were not clinically significant. The heart rate increased, with values staying within the limits of physiological range. The speed of onset of midazolam’s clinical effects depends on age and dose. The lower age and dose correlated with the higher behavior score. The effectiveness of midazolam treatment is 97.8 %. Unwillingness of child to receive midazolam is predictor for disruptive behavior during sedation. 1.8 % of all sedation cases showed paradoxical reactions. The administration of midazolam in dose of 0.5 mg per 1 kg of child’s body weight is safe and could be recommended for dental treatment in pediatric dentistry.
Melanocortin Pathways: Suppressed and Stimulated Melanocortin-4 Receptor (MC4R)
Authors: HAINER V. , ALDHOON HAINEROVÁ I. , KUNEŠOVÁ M. , TAXOVÁ BRAUNEROVÁ R. , ZAMRAZILOVÁ H. , BENDLOVÁ B.
Published: October 2020

Leptin-melanocortin pathway plays an essential role in the body weight regulation. Enhanced melanocortin signaling in the hypothalamus results in both decreased food intake and increased energy expenditure. The discovery of monogenic obesities with dysfunction of melanocortin-4 receptor (MC4R) greatly contributed to understanding of energy balance regulation. This review presents phenotypical characterization and prevalence of the MC4R gene mutations. Genome-wide association studies revealed that MC4R gene is significantly related not only to monogenic obesities but also to common obesity. An interaction of variants in the MC4R gene with fat mass and obesity associated (FTO) gene significantly increases the risk for obesity, particularly in adolescence. On the other hand, about 15 % of the MC4R gene variants result in a gain of function that protects against obesity and is associated with favorable metabolic profile. Long-term attempts to activate the MC4R have recently been finalized by a discovery of setmelanotide, a novel specific MC4R agonist that is devoid of untoward cardiovascular side-effects. The employment of specific MC4R agonists may open new horizons not only in the treatment of rare monogenic obesities but also in some common obesities where stimulation of MC4R could be achieved.
Dental Composites – a Low-Dose Source of Bisphenol A?
Authors: ŠIMKOVÁ M. , TICHÝ A. , DUŠKOVÁ M. , BRADNA P.
Published: October 2020

Dental composite materials often contain monomers with bisphenol A (BPA) structure in their molecules, e.g. bisphenol-A glycidyl dimethacrylate (Bis-GMA). In this study, it was examined whether dental restorative composites could be a low-dose source of BPA or alternative bisphenols, which are known to have endocrine-disrupting effects. Bis-GMA-containing composites Charisma Classic (CC) and Filtek Ultimate Universal Restorative (FU) and “BPA-free” Charisma Diamond (CD) and Admira Fusion (AF) were examined. Specimens (diameter 6 mm, height 2 mm, n=5) were light-cured from one side for 20 s and stored at 37 °C in methanol which was periodically changed over 130 days to determine the kinetics of BPA release. BPA concentrations were measured using a dansyl chloride derivatization method with liquid chromatography – tandem mass spectrometry detection. The amounts of BPA were expressed in nanograms per gram of composite (ng/g). BPA release from Bis-GMA-containing CC and FU was significantly higher compared to “BPA-free” CD and AF. The highest 1-day release was detected with FU (15.4±0.8 ng/g), followed by CC (9.1±1.1 ng/g), AF (2.1±1.3 ng/g), and CD (1.6±0.8 ng/g), and the release gradually decreased over the examined period. Detected values were several orders of magnitude below the tolerable daily intake (4 µg/kg body weight/day). Alternative bisphenols were not detected. BPA was released even from “BPA-free” composites, although in significantly lower amounts than from Bis-GMA-containing composites. Despite incubation in methanol, detected amounts of BPA were substantially lower than current limits suggesting that dental composites should not pose a health risk if adequately polymerized.
Endocrine Disruptors, Obesity, and Cytokines - How Relevant Are They to PCOS?
Authors: ŠIMKOVÁ M. , VÍTKŮ J. , KOLÁTOROVÁ L. , VRBÍKOVÁ J. , VOSÁTKOVÁ M. , VČELÁK J. , DUŠKOVÁ M.
Published: October 2020

As environmental and genetic components contribute to the PCOS expression, we compared levels of endocrine disruptors, steroid hormones, cytokines, and metabolic parameters in twenty healthy, nine normal-weight PCOS women, and ten obese PCOS women. Steroid hormones, bisphenols (BPA, BPS, BPF, BPAF) and parabens (methyl-, ethyl-, propyl-, butyl-, benzyl-parabens) were measured by liquid chromatography-tandem mass spectrometry. Differences between the groups were assessed using the Mann-Whitney U test. Spearman correlation coefficients were calculated for the individual parameters relationship. Significantly higher levels of BPA, anti-Müllerain hormone, lutropine, lutropine/folitropine ratio, testosterone, androstenedione, 7β-OH-epiandrosterone, and cytokines (IL-6, VEGF, PDGF-bb), were found in normal-weight PCOS women compared to controls. Between normal-weight and obese PCOS women, there were no differences in hormonal, but in metabolic parameters. Obese PCOS women had significantly higher insulin resistance, fatty-liver index, triglycerides, cytokines (IL-2, IL-13, IFN-γ). In healthy, but not in PCOS, women, there was a positive correlation of BPA with testosterone, SHBG with lutropine, and folitropine, while testosterone negatively correlated with SHBG. In obese women with PCOS, insulin resistance negatively correlated with SHBG and estradiol. No differences were observed in the paraben exposure. Levels of BPA were higher in PCOS women, indicating its role in the etiology. Obesity significantly worsens the symptoms.
Aging, Hormones and Receptors
Authors: HILL M. , TŘÍSKALA Z. , HONCŮ P. , KREJČÍ M. , KAJZAR J. , BIČÍKOVÁ M. , ONDŘEJÍKOVÁ L. , JANDOVÁ D. , STERZL I.
Published: October 2020

Ageing is accompanied by deterioration in physical condition and a number of physiological processes and thus a higher risk of a range of diseases and disorders. In particular, we focused on the changes associated with aging, especially the role of small molecules, their role in physiological and pathophysiological processes and potential treatment options. Our previously published results and data from other authors lead to the conclusion that these unwanted changes are mainly linked to the hypothalamic-pituitary-adrenal axis can be slowed down, stopped, or in some cases even reversed by an appropriate treatment, but especially by a life-management adjustment.
Orbital Floor Blow-Out Fractures: Ultrasonography, Postoperative Complications and Rehabilitation
Authors: Imbrasienė Daiva , Valasevičienė Alvyra Veronika , Daveckaitė Akvilė , Kregždytė Rima
Published: October 2020

The aim of this retrospective study was to analyze indications and the efficiency of post-operative rehabilitation in patients with orbital floor blow-out fractures. The selected patients were with orbital floor blow-out fractures and post-operative rehabilitation; eight case records were traced. The symptoms of the eyes (eye position and movements, coordimetry, ultrasonography) were noted before and after surgical correction and rehabilitation treatment. The data were statistically analyzed using a computer software package, SPSS version 16.0. A value of p < 0.05 was considered as statistically significant. All eight (100%) patients were men. The average age was 19.88 ± 8.25 years (14–34 years). The most common complaint was diplopia, it was in eight (100%) patients’ numb of affected face side was in two (28.6%), vertigo in one (12.5%), nausea in one (12.5%) patient. Post–operative complications were: diplopia – eight (100%) patients, postoperative scar – three (37.5%), eyelid swelling – four (50%), haematoma – one (12.5%) patient. After rehabilitation post-operative symptoms (postoperative scar, eyelid swelling, haematoma) decreased significantly (p < 0.05). Insignificant diplopia was left in seven (87.5%) (p > 0.05) patients, but it did not disturb their general activities. Patients were not treated surgically, neither they got correction with prismatic spectacles after rehabilitation. One (12.5%) patient was under supervision. Before rehabilitation ultrasonography was done for five (62.5%) patients. Ultrasonography was repeated only for one (12.5%) patient after rehabilitation. Coordimetry was done for all patients while they were being treated in order to find out the efficiency of rehabilitation. Rehabilitation can be recommended to patients with post-operative complications such as diplopia, swelling, post-operative scar. Treatment effect should be objectified by ultrasonography.Keywords: rehabilitation, orbital floor fracture, postoperative complications, ultrasonography.
Effectiveness of the Out-Patient Rehabilitation and Home Exercise Program to the Patients with Lumbar Disc Herniation
Authors: Janulis Marius , Leimonienė Lina , Jazepčikienė Edita
Published: October 2020

In scientific literature there are few studies dealing with the effectiveness of home exercise program in patients with low back pain. These issues are very important since the out-patient institutions provide just temporal and short-term physical therapy. Patients having gone through it are left without the supervision of physical therapist and depend only on the effectiveness of home exercise program. There is also lack of studies in which the effectiveness of out-patient treatment and home exercise program is compared. The aim of the study was to assess the effectiveness of the out-patient rehabilitation and home exercise program for patients with lumbar disc herniation. Contingent: there were 60 patients from 20 to 60 years of age (average age 40.7 ± 2.2) investigated, 27 women and 33 men. The patients with strong low back pain had been treated in the Department of Vertebroneurology and in the Department of Physical Medicine and Rehabilitation of Kaunas Clinical Hospital. All the patients were diagnosed with the intervertebral disc herniation, no surgical treatment was applied before. After in-patient rehabilitation one group was pointed to the out-patient rehabilitation (30 patients), the second group participated in home treatment (30 patients, too). This group was called home exercise program group. These patients were motivated to do exercises 14 days, once a day at home and agreed to participate in home rehabilitation program. Home exercise program for these patients was composed. Methods of the investigation: low back pain (using numerical analogue pain scale), the level of functional disability (using RolandMorris questionnaire) and the quality of life (EQ-5D questionnaire) before and after treatment were evaluated.Results: after out-patient rehabilitation, low back pain and functional disability decreased and the quality of life increased more than after home exercise program. Conclusion: 1. After out-patient rehabilitation, low back pain and the level of functional disability decreased and the quality of live increased more than after home exercise program. 2. Home exercise program reduced low back pain and the level of functional disability, but it did not change the quality of life (p > 0.05). Practical recommendation: low back pain, the level of functional disability decreased and quality of life after out-patient rehabilitation improved more in comparison to those patients, who applied home exercise program and it is recommended to continue out-patient rehabilitation after in-patient treatment.Keywords: low back pain, intervertebral disc herniation, out-patient rehabilitation, home exercise program.
Impact of Nutrition and Physical Activity on Behaviour and Academic Achievements in Pupils
Authors: Dabriegaitė Vilija , Dudonienė Vilma , Imbrasienė Daiva , Kesminas Rolandas
Published: October 2020

Nutrition is the main component of children’s health. In order to be completely healthy children need good nutrition and substantial physical activity [1]. Nutritional habits acquired in childhood and adolescence are maintained during adulthood. Scientists emphasize breakfast eating because breakfast ensures attention-concentration, memory and school achievements during morning sessions [2]. Eating breakfast provides energy for the brain and improves learning. Poor nutrition is associated with poor academic achievements. Under-nutrition has negative effect on pupils’ behaviour, attendance of lessons and even behaviour in adulthood [3]. Nutrition of pupils should be well-balanced and variable, offering more fresh fruit, whole grains and a greater variety of vegetables [4]. It is recommended to reduce levels of fat and sodium and increase fiber [5], and in the first part of day to drink more fresh water in order to improve attention and behaviour [2]. The aim was establish the interrelationship between nutrition, behaviour and academic achievements in pupils. Conclusions. Breakfast is an essential meal in pupils’ day; regular habit of eating breakfast has beneficial influence on attentionconcentration, memory and school achievements. Well-balanced pupils’ nutrition decreases antisocial and aggressive behaviour. Physical activity reduces manifestation of negative emotions and stress in pupils.Keywords: physical activity, nutrition, behaviour, academic achievements.
Comparison of the Effect of Different Physical Therapy Methods on Lumbopelvic Stability among People with Low Back Pain
Authors: Knatauskaitė Justė
Published: October 2020

Research background. The majority of persons suffer from low back pain and prevalence of it seeks about 84%. Chronic low back pain is the second cause for people to go to their general practitioner. Many studies are done about treatment of chronic low back pain; however, complaints about back pain are increasing. Therefore we are going to find out which of the three our applied methods is the best for treating low back pain. The aim of the study was to compare the impact of different physical therapy methods on lumbopelvic stability control among people with chronic low back pain. Methods. 30 people with low back pain were participating in this study. Following factors were estimated before and after eight physical therapy sessions: intensity of pain by using the scale of numbers (SAS); lumbopelvic stability control by using “Stabilizer” pressure biofeedback unit; functional motions performance capacity by doing functional tasks. Results. Statistically significant changes were not found after the evaluation of lumbopelvic stability control under the method of Redcord sliding suspension system, elastic resistance and body weight exercises before and after physical therapy sessions. Statistically significant correlations were found between lumbopelvic stability control and pain intensity in those groups where people were training under the methods of elastic resistance and body weight exercises (p < 0.05). Statistically significant correlations were found between lumbopelvic stability control and functional motions performance capacity in those groups where people were training under the methods of Redcord sliding suspension system and body weight exercises (p < 0.05). Conclusion: statistically significant change was not found between three intervention groups after physical therapy; therefore neither of three methods applied in this study was better than the others.Keywords: chronic low back pain, lumbopelvic stability control, functional movement performance capacity, physical therapy.
The Effect of Spine Stability Exercise on Dynamic Postural Control and Possibility to Have Ankle Injury in Basketball Players
Authors: Juknevičiūtė Dovilė
Published: October 2020

Ankle ligaments injury is a common trauma in athletes, when proprioception, sensomotor control, muscle strength and balance are disturbed. Possibility to have trauma remains high, thus, trauma prevention plays a very important role. The aim of the study was to evaluate dynamic postural control and possibility to have ankle injury before and after spine stability exercise. Basketball players’ dynamic postural control was assessed using the modified Star Excursion Balance test and risk to experience ankle trauma – the calculation of the combined result. Before applying spine stability exercise basketball players who had not had degree II ankle sprain had better dynamic postural control in all directions than basketball players who had had degree II ankle sprain. After eight weeks of applying spine stability exercise dynamic postural control of basketball players who had had degree II ankle sprain improved significantly (p < 0.05) in all directions, dynamic postural control of but basketball players who not had degree II ankle sprain improved, but insignificantly (p > 0.05). Before applying spine stability exercise, 78% of basketball players who had had degree II ankle sprain and 22% basketball players who not had degree II ankle sprain had higher possibility to experience ankle trauma, but after eight weeks of spine stability exercise 11% of basketball players in both groups had higher possibility to experience ankle trauma. Spine stability exercise had positive effect on dynamic postural control and reduced possibility to experience ankle injury.Keywords: dynamic postural control, ankle injury, spine stability, modified Star Excursion Balance test.
Investment in the Agroindustrial Sector as a Factor of Sustainable Development of the State
Authors: Erlygina E. , Vasilyeva A.
Published: October 2020

The agroindustrial sector plays a significant role in the Russia economy. The main condition for the stable functioning and development of the agroindustrial sector is the dynamic and effective development of investment activities. Problems of investment development of agriculture negatively affect the economic sphere of agricultural production. It is necessary to optimize the investment policy, which will contribute to the emergence of long-term investments in agriculture, ensuring sustainable socio-economic development of the industry.
Crime and External Migration in the Regions of the Russian Federation as an Indicator for Studying Social and Ethno-Cultural Tensions, as Well as the Risk of the Spread of Terrorist and Extremist Ideology: Defenseless Subjects of the Russian Federation (1st half of 2020)
Authors: Kuzina N.
Published: October 2020

With the economic and social crisis, the methods of making forecasts of social tension in the regions of the Russian Federation are relevant. They are needed for the regional and federal authorities to take timely measures to reduce tension. A kind of social tension is ethno-social tension. It is significant in the historically multi-ethnic regions of the Russian Federation, in large cities and in the constituent entities of the Federation with a high activity of the flow of external migrants. We analyzed the state of ethno-social tension in the regions of the Russian Federation during the coronavirus pandemic based on preliminary data from the General Prosecutor’s Office of Russia and the Ministry of Internal Affairs of Russia on registered crimes and registration / deregistration of foreign migrants.