bluuebunny/crossref_metadata_2025 huggingface dataset:
Prognostic model for esophagogastric variceal rebleeding after endoscopic treatment in liver cirrhosis: A Chinese multicenter study
Authors: Zhan Jun-Yi , Chen Jie , Yu Jin-Zhong , Xu Fei-Peng , Xing Fei-Fei , Wang De-Xin , Yang Ming-Yan , Xing Feng , Wang Jian , Mu Yong-Ping
Published: December 2024

BACKGROUND

Rebleeding after recovery from esophagogastric variceal bleeding (EGVB) is a severe complication that is associated with high rates of both incidence and mortality. Despite its clinical importance, recognized prognostic models that can effectively predict esophagogastric variceal rebleeding in patients with liver cirrhosis are lacking.

AIM

To construct and externally validate a reliable prognostic model for predicting the occurrence of esophagogastric variceal rebleeding.

METHODS

This study included 477 EGVB patients across 2 cohorts: The derivation cohort (n = 322) and the validation cohort (n = 155). The primary outcome was rebleeding events within 1 year. The least absolute shrinkage and selection operator was applied for predictor selection, and multivariate Cox regression analysis was used to construct the prognostic model. Internal validation was performed with bootstrap resampling. We assessed the discrimination, calibration and accuracy of the model, and performed patient risk stratification.

RESULTS

Six predictors, including albumin and aspartate aminotransferase concentrations, white blood cell count, and the presence of ascites, portal vein thrombosis, and bleeding signs, were selected for the rebleeding event prediction following endoscopic treatment (REPET) model. In predicting rebleeding within 1 year, the REPET model exhibited a concordance index of 0.775 and a Brier score of 0.143 in the derivation cohort, alongside 0.862 and 0.127 in the validation cohort. Furthermore, the REPET model revealed a significant difference in rebleeding rates (P < 0.01) between low-risk patients and intermediate- to high-risk patients in both cohorts.

CONCLUSION

We constructed and validated a new prognostic model for variceal rebleeding with excellent predictive performance, which will improve the clinical management of rebleeding in EGVB patients.
Association between intra-pancreatic fat deposition and diseases of the exocrine pancreas: A narrative review
Authors: Ye Jing , Wang Jian-Guo , Liu Rong-Qiang , Shi Qiao , Wang Wei-Xing
Published: December 2024

Intrapancreatic fat deposition (IPFD) has garnered increasing attention in recent years. The prevalence of IPFD is relatively high and associated with factors such as obesity, age, and sex. However, the pathophysiological mechanisms underlying IPFD remain unclear, with several potential contributing factors, including oxidative stress, alterations in the gut microbiota, and hormonal imbalances. IPFD was found to be highly correlated with the occurrence and prognosis of exocrine pancreatic diseases. Although imaging techniques remain the primary diagnostic approach for IPFD, an expanding array of biomarkers and clinical scoring systems have been identified for screening purposes. Currently, effective treatments for IPFD are not available; however, existing medications, such as glucagon-like peptide-1 receptor agonists, and new therapeutic approaches explored in animal models have shown considerable potential for managing this disease. This paper reviews the pathogenesis of IPFD, its association with exocrine pancreatic diseases, and recent advancements in its diagnosis and treatment, emphasizing the significant clinical relevance of IPFD.
Current status of drug therapy for chronic hepatitis B
Authors: Jiang Chuang , Zhang Zhi-Hong , Li Jia-Xin
Published: December 2024

In this editorial, we comment on the article by Meng et al . Chronic hepatitis B (CHB) is a significant global health problem, particularly in developing countries. Hepatitis B virus (HBV) infection is one of the most important risk factors for cirrhosis and hepatocellular carcinoma. Prevention and treatment of HBV are key measures to reduce complications. At present, drug therapy can effectively control virus replication and slow disease progression, but completely eliminating the virus remains a challenge. Anti-HBV treatment is a long-term process, and there are many kinds of antiviral drugs with different mechanisms of action, it is essential to evaluate the safety and efficacy of these drugs to reduce side effects and improve patients’ compliance. We will summarize the current status of CHB drug treatment, hoping to provide a reference for the selection of clinical antiviral drugs.
Prospects of elafibranor in treating alcohol-associated liver diseases
Authors: Cui Wei-Tong , Xue Hua-Ru , Wei Dian-Fang , Feng Xiao-Yu , Wang Kai
Published: December 2024

Alcohol-related liver disease (ALD), which is induced by excessive alcohol consumption, is a leading cause of liver-related morbidity and mortality. ALD patients exhibit a spectrum of liver injuries, including hepatic steatosis, inflammation, and fibrosis, similar to symptoms of nonalcohol-associated liver diseases such as primary biliary cholangitis, metabolic dysfunction-associated steatotic liver disease, and nonalcoholic steatohepatitis. Elafibranor has been approved for the treatment of primary biliary cholangitis and has been shown to improve symptoms in both animal models and in vitro cell models of metabolic dysfunction-associated steatotic liver disease and nonalcoholic steatohepatitis. However, the efficacy of elafibranor in treating ALD remains unclear. In this article, we comment on the recent publication by Koizumi et al that evaluated the effects of elafibranor on liver fibrosis and gut barrier function in an ALD mouse model. Their findings indicate the potential of elafibranor for ALD treatment, but further experimental investigations and clinical trials are warranted.
Ryšys tarp vitamino D ir paprastosios psoriazės. Literatūros apžvalga
Authors: Malūkaitė Evelina , Gineitytė Ignė , Kriukas Artūras
Published: December 2024

Tyrimo tikslas. Išanalizuoti naujausią mokslinę literatūrą apie psoriazės ir vitamino D ryšį klinikinėje praktikoje. Metodika. Literatūros paieška atlikta „PubMed“, „ScienceDirect“, „ResearchGate“ elektroninėse duomenų bazėse. Atrinkti straipsniai buvo publikuoti nuo 2019 m. iki 2024 m. Rezultatai. Psoriazė yra T ląstelių medijuota autoimuninė liga, kurios patogenezėje svarbiausi uždegimą skatinantys citokinai. Jie sukelia keratinocitų hiperproliferaciją – lėtinį odos uždegimą, pasireiškiantį plokštelėmis. Normaliomis sąlygomis vitaminas D užtikrina tinkamą odos barjerinę funkciją, slopindamas ląstelinį imuninį atsaką: mažina uždegimą skatinančių citokinų išsiskyrimą, keratinocitų dauginimąsi ir diferenciaciją. Mokslinės literatūros apžvalgos duomenimis, hipovitaminozė lemia psoriazės ligos atsiradimą ir progresavimą. Sergantieji psoriaze statistiškai reikšmingai dažniau turi žemesnį vitamino D kiekį nei sveika populiacija. Vitamino D analogai sėkmingai taikomi kaip papildoma psoriazės gydymo priemonė. Siekiant palengvinti ligos eigą, reikia imtis priemonių hipovitaminozei koreguoti. Išvados. Sumažėjęs vitamino D kiekis yra viena iš galimų psoriazės priežasčių, tačiau šiai hipotezei pagrįsti reikalingos išsamesnės studijos.
Kalcifediolis prieš cholekalciferolį: pažangus sprendimas koreguojant vitamino D stygių
Authors: Vitkauskas Lukas
Published: December 2024

Vitaminas D yra riebaluose tirpus steroidas, svarbus kalcio ir fosforo apykaitai, kaulų bei raumenų funkcijai ir imuninei sistemai. Jo stygius gali sukelti įvairių sveikatos problemų, tokių kaip osteoporozė, raumenų silpnumas ir imuninės sistemos sutrikimai. Tyrimai rodo, kad vitaminas D taip pat galėtų padėti sumažinti kai kurių vėžio rūšių, tokių kaip storosios žarnos, krūties ir prostatos vėžys, riziką. Preparatai, tokie kaip cholekalciferolis (vitaminas D3) ir kalcifediolis (25-hidroksivitaminas D3), yra taikomi vitamino D stygiui koreguoti. Kalcifediolis yra veiksmingesnė alternatyva nei cholekalciferolis, nes jis greičiau didina vitamino D kiekį kraujyje ir nepriklauso nuo kepenų fermentų metabolizmo proceso. Be to, kalcifediolis yra naudingesnis pacientams, sergantiems kepenų ligomis arba nutukimu.
«35 maneras de morir en Mauthausen»: el trauma concentracionario en viñetas
Authors: Bermúdez Luana
Published: December 2024

En este trabajo analizamos cómo se ha representado la experiencia concentracionaria de los deportados españoles a través de las novelas gráficas Esperaré siempre tu regreso, de Jordi Peidro (2016), y El fotógrafo de Mauthausen, una colaboración firmada por Salva Rubio, Pedro J. Colombo y Aintzane Landa (2018). En primer lugar, estudiaremos la relación entre rigor histórico y creación, pues estas obras se nutren de documentos auténticos que los autores retoman y relaboran, tales como testimonios orales, noticias de periódicos, cartas, pancartas o fotos conservadas en archivos como el NARA, el MHC o el AMM. En segundo lugar, analizaremos algunas estrategias gráficas utilizadas para hacer énfasis en trauma vivido por los deportados españoles.
Cosas para recordar. Un proyecto para el estudio de la Historia de España, a través de las memorias familiares, partiendo del cómic Regreso al Edén, de Paco Roca.
Authors: Mora Pérez Mónica
Published: December 2024

Presentamos la experiencia sobre el uso didáctico del cómic “Regreso al Edén” de Paco Roca, desarrollada por el Departamento de Geografía e Historia del IES Alonso Quijano (2020-2024). En esta obra, el autor organiza la narración en torno a la conservación de una fotografía, objeto que abre el campo a la reconstrucción de la historia familiar. El análisis del cómic revela la aportación de Paco Roca al tratamiento de las memorias familiares bajo el franquismo. El cómic sirve a los alumnos como fuente histórica, y es un modelo para realizar trabajos de investigación, a partir de la elección de un objeto familiar, que les permita anudar la memoria transmitida con el conocimiento aportado por el estudio académico de la Historia.
Musicalización, adaptación y reinterpretación. Impresiones de P. Craig Russell en torno a Pélleas et Mélisande de Claude Debussy
Authors: Silvela calvo Alejandro
Published: December 2024

P. Craig Russell se ha convertido en uno de los principales referentes sobre musicalización del cómic trasladando ideas musicales a obras plásticas. En el presente artículo me propongo a elaborar un análisis sobre su adaptación de la obra simbolista Pélleas et Mélisande. La obra, perteneciente al dramaturgo Maurice Maeterlinck y llevada al panorama operístico por Claude Debussy, podría considerarse una de las obras más personales de Russell y abiertas a la interpretación debido al carácter simbolista de la obra. Mientras en otras adaptaciones opta por mayor importancia al papel de la música, nos encontramos en Pélleas et Mélisande con una adaptación que plasma una gran cantidad de ideas de la obra original, concediendo importancia al simbolismo de la misma.
De la Rusia soviética a la viñeta española: los voluntarios de la División Azul en el cómic
Authors: Acosta López Alejandro
Published: December 2024

La División Azul ha sido uno de los episodios del pasado siglo XX español que más se ha recordado y divulgado. El propósito de este artículo es analizar las representaciones de la División Azul en el mundo del cómic tomando en consideración cuatro propuestas: algunas historias de la segunda época de Hazañas bélicas, y las novelas gráficas División Azul (2013), Hasta Nóvgorod: crónica de un divisionario (2020) y 1941: Voljov (2021). Particularmente, el artículo examina la influencia de la literatura mnemónica de los veteranos de guerra en la construcción narrativa y en el imaginario visual de los diferentes autores de cómic.
Enhancing Interoperability in the Web of Things: A Reference Architecture Approach
Authors: Albarrak Khalied
Published: December 2024

The concept of the Internet of Things (IoT) has fundamentally redefined the connectivity landscape by integrating physical devices with the Internet for data exchange. The Web of Things (WoT) takes this integration a step further by embedding IoT devices within the web, thus facilitating their interoperability. However, the inherent complexity of WoT architecture requires a layer of abstraction to simplify development and integration. Patterns and reference architectures (RAs) provide such an abstraction, modeling solutions for recurrent problems within this domain. In this paper, we aim to develop an RA for the WoT ecosystem. We use architectural patterns to build the RA of the WoT. Here, we present the WoT gateway pattern, which provides a clear and adaptable framework for integrating diverse IoT devices, ensuring seamless communication and functionality within the broader web ecosystem. The purpose of this pattern is twofold: to ensure the interoperability of WoT implementations and to serve as a foundational guide for developers navigating the multifaceted challenges of WoT system design. The pattern also paves the way for building an RA for IoT environments.
KEYWORDS
Architectural patterns, Internet of Things, reference architecture, web development, web science, WoT
Reliably measuring learning-dependent distractor suppression with eye tracking
Authors: Kim Andy J. , Grégoire Laurent , Anderson Brian A.
Published: December 2024

In the field of psychological science, behavioral performance in computer-based cognitive tasks often exhibits poor reliability. The absence of reliable measures of cognitive processes contributes to non-reproducibility in the field and impedes the investigation of individual differences. Specifically in visual search paradigms, response time-based measures have shown poor test–retest reliability and internal consistency across attention capture and distractor suppression, but one study has demonstrated the potential for oculomotor measures to exhibit superior reliability. Therefore, in this study, we investigated three datasets to compare the reliability of learning-dependent distractor suppression measured via distractor fixations (oculomotor capture) and latency to fixate the target (fixation times). Our findings reveal superior split-half reliability of oculomotor capture compared to that of fixation times regardless of the critical distractor comparison, with the reliability of oculomotor capture in most cases falling within the range that is acceptable for the investigation of individual differences. We additionally find that older adults have superior oculomotor reliability compared with young adults, potentially addressing a significant limitation in the aging literature of high variability in response time measures due to slower responses. Our findings highlight the utility of measuring eye movements in the pursuit of reliable indicators of distractor processing and the need to further test and develop additional measures in other sensory domains to maximize statistical power, reliability, and reproducibility.
The use of new psychoactive substances among young adults in Romania
Authors:   Department of Ethics and Social Sciences, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Targu Mures, Romania, Salcudean Andreea , Teresneu Bianca Ioana ,   Faculty of Medicine,“George Emil Palade” University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania, Cimpian Dora Mihaela ,   Psychiatry Clinic 1, Mures County Clinical Hospital, Targu Mures, Romania, Sasu Andreea Bianca ,   Psychiatry Clinic 1, Mures County Clinical Hospital, Targu Mures, Romania, Nan Andreea Georgiana ,   Psychiatry Clinic 1, Mures County Clinical Hospital, Targu Mures, Romania, Craciun Elena Ramona ,   Department of Psychology, The Child and Childhood Association, Targu Mures, Romania, Bodo Cristina ,   Psychiatry Clinic 2, Mures County Clinical Hospital, Targu Mures, Romania, Cozma Melania ,   Department of Ethics and Social Sciences, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Targu Mures, Romania, Strete Elena Gabriela ,   Department of Psychiatry, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Targu Mures Romania, Enatescu Virgil Radu ,   Department VIII Neuroscience - Discipline of Psychiatry, “Victor Babes” University of Medicine and Pharmacy Timisoara,Romania
Published: December 2024

Background and objectives. The consumption of new psychoactive substances (NPS), particularly among young people, remains a significant public health issue. The principal objective of this study was to identify the incidence and prevalence of NPS use among young people in Romania and the impact of the consumption on their mental health. Materials and methods. A cross-sectional study was conducted on a sample of 231 Romanian participants on March-April 2023. Data were collected through an online questionnaire and analyzed using GraphPad and Excel statistical software. Results. The prevalence of NPS use was 38.10% within the sample The analyzed data indicated an increased incidence of NPS use among male participants. Notably, most respondents who reported NPS use were students, accounting for 23.38% of users. Among the total of 88 NPS users, 22.68% consumed synthetic cannabinoids, 14.09% bath salts, and 13.75% used mephedrone. Less frequently consumed substances included synthetic opioids, methamphetamines, synthetic piperazines, Salvia divinorum, and MDPV. A significant proportion of users reported severe psychiatric symptoms including psychosis, depression and anxiety. Among non-users, awareness of the side effects of NPS influenced over half of them to avoid such substances. Conclusions. NPS use impacts predominantly young people. Organizing prevention and information campaigns about the implications of NPS use and its immediate harmful effects could help reduce its prevalence among young individuals.
Therapeutic potential of SGLT-2 inhibitors and DDP4 inhibitors in elderly patients with type 2 diabetes mellitus and benign prostatic hyperplasia
Authors:   Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt, Soliman Amin Roshdy , Ahmed Rabab Mahmoud ,   Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt, Soliman Haytham ,   Cairo University, Cairo, Egypt, Marzouk Khaled Sadek ,   Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt, Abdelaziz Tarek Samy ,   Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt, Abdelghany Reham ,   Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt
Published: December 2024

Background. Benign prostatic hyperplasia (BPH) has recently been linked to diabetes mellitus and insulin resistance. This study aims to explore whether the use of either sodium-glucose co-transporter-2 (SGLT-2) inhibitors or dipeptidyl peptidase-4 (DPP-4) inhibitors is associated with favorable outcomes in prostate volume and symptoms. Methods. This is a before-and-after study involving 57 elderly male patients with type 2 diabetes mellitus and BPH, who were recruited and followed up for one year. Twenty-seven patients were prescribed SGLT-2 inhibitors (Dapagliflozin 10 mg), and thirty patients were prescribed DPP-4 inhibitors (Sitagliptin 100 mg). Prostate volume, International Prostate Symptom Score (IPSS), and Pittsburgh Sleep Quality Index (PSQI) were assessed in all patients. Results. The use of either SGLT-2 inhibitors or DPP-4 inhibitors was associated with a statistically significant decrease in prostate volume after one year of treatment (p = 0.04 for SGLT-2 inhibitors and p = 0.02 for DPP-4 inhibitors). Statistically significant reductions were found in both groups regarding post-voiding urine volume after one year of treatment compared to baseline levels (p = 0.014 for SGLT-2 inhibitors and p = 0.017 for DPP-4 inhibitors). At the end of the follow-up period, there was a statistically significant reduction in IPSS scores (p = 0.02 for SGLT-2 inhibitors and p = 0.03 for DPP-4 inhibitors). Similarly, the use of either DPP-4 inhibitors or SGLT-2 inhibitors was associated with a statistically significant improvement in nocturia and sleep quality (PSQI score) (p = 0.012 for SGLT-2 inhibitors and p = 0.01 for DPP-4 inhibitors). Post-hoc analysis showed that DPP-4 inhibitors were superior to SGLT-2 inhibitors in reducing prostate volume and symptoms (p < 0.05). Conclusion. Both SGLT-2 inhibitors and DPP-4 inhibitors improve prostate volume and symptoms in patients with diabetes mellitus and BPH. Notably, DPP-4 inhibitors exhibited superiority over SGLT-2 inhibitors in terms of reducing prostate volume and alleviating symptoms. Larger-scale studies are required to confirm these favorable effects.
The impact of radiation therapy on thyroid function in patient with head and neck tumors
Authors:   Department of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq, Al-Taweel Firas Fekri Najeeb , Kadhim Satar Majeed ,   Department of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq
Published: December 2024

Background. Head and neck cancers (HNC) accounted for 1,518,133 new cases and 510,771 new deaths worldwide. The first reports of hypothyroidism following radiotherapy (RT) for HNC were published in the 1960s. The objective of this study was to ascertain the frequency of thyroiditis in patients with HNC and to establish the threshold of radiation dose volume for radiation-induced hypothyroidism in HNC. Methods. This was a prospective study of 35 patients with HNC treated with IMRT-VMAT. The following characteristics were examined: age, gender, comorbidity, initial tumor site, histology, surgical margin resection, radiation therapy dosage, V40, V50, V60 (percentage of thyroid tissue volume), 95% dose received, mean dose, minimum dose, and maximum dose. Thyroid assessment was performed using ultrasonography of the neck. Thyroid function was determined by TFT tests (TSH, free T3, and free T4), which were done at baseline before treatment and after RT for each case. Results. In this study, the mean age was 57.71 ± 11.43 years, with males comprising 68.6% (24 patients) and females comprising 31.4% (11 patients). Regarding TSH, the results showed that post-RT, the mean level of TSH was significantly higher than pretreatment, with a significant difference (P = 0.009). Regarding fT3, the results showed that post-RT, the mean level of fT3 was significantly lower than pretreatment, with a significant difference (P = 0.007). Regarding fT4, the results showed that post-RT, the mean level of fT4 was significantly lower than pretreatment, with a significant difference (P = 0.015). In addition, the mean 95% dose was 6.8 Gy (median = 4 Gy). The percentages of thyroid tissue volumes at V40, V50, and V60 were 79.47%, 39.28%, and 38.02%, respectively. The incidence of hypothyroidism was 14.3%, and the euthyroid incidence rate was 85.7%. Conclusions. There is a strong correlation between radiation therapy doses exceeding 66 Gy and the occurrence of hypothyroidism. The levels of fT3 and fT4 decreased after RT, while TSH levels increased. In dosimetry, the mean 95% dose was 6.8 Gy. The percentages of thyroid tissue volumes at V40, V50, and V60 were 79.47%, 39.28%, and 38.02%, respectively. The incidence of hypothyroidism was 14.3%, and the euthyroid incidence rate was 85.7%.
Knowledge, attitude, and beliefs of interns towards brain death diagnosis
Authors:   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Basubrain Omar Sami , Alwafi Thekra Abdulhafith ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Alandijani Mohammed Ahmed ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Bakhedr Sarah Abdullah Omar ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Alhazmi Mohammed Abdulelah ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Hamzah Asma Ahmad Yusuf ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Krenshi Abdullah Osamah ,   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia
Published: December 2024

Objective. To evaluate the knowledge and attitudes of interns regarding brain death diagnosis and organ donation. Methods. A cross-sectional survey was administered to 142 interns at Umm Al-Qura University to assess their understanding of the legal definitions, diagnostic criteria, procedures, and attitudes towards organ donation. Results. Significant knowledge gaps were identified, with many interns demonstrating a limited understanding of key aspects of brain death. While some expressed confidence in their diagnostic abilities, concerns about misdiagnosis and premature organ donation were also prevalent. Conclusion. Although limited by its single-center design, this study highlights the need for enhanced education on brain death in medical training programs. Further research, particularly multicenter studies, is necessary to validate these findings and develop targeted educational interventions to improve interns' comprehension and address their concerns.
Numerical Simulation of Surface Pressure and Temperature Distribution Along a Cone at Supersonic Mach Numbers Using CFD
Authors: Shaikh Javed Shoukat , Pathan Khizar Ahmed , Khan Sher Afghan
Published: December 2024

The primary focus of this study is to use numerical simulations to analyze the static temperature and surface pressure distribution along the slant length of a cone at different Mach numbers and a range of semi-cone angles. Computational fluid dynamics (CFD) analysis numerically simulates temperature and surface pressure distribution. This research considers parameters such as supersonic Mach numbers, semi-cone angles, and different locations along the slant length of a cone. The study examines Mach numbers of 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 4.5, and 5.0, along with cone angles ranging from 3° to 21°. The static temperature and pressure (P/Pa) results are measured at different locations (x/L) along the slant length of the cone, ranging from 0.1 to 1. The results for static temperature and pressure distribution obtained by CFD analysis are compared with results obtained by regression model at various Mach numbers and constant semi-cone angle (θ) = 12°. The results from the CFD analysis and the findings of the regression methodology are in agreement. This study found that the Mach number, semi-cone angle, and the various locations along the cone's slant length significantly impact the variation of static temperature and surface pressure distribution. As the Mach number and the semi-cone angle increase, the temperature and pressure distribution along the slant length of the cone also increase.
Influence of MHD Flow on Shrinking Sheet with Partial Slip and Heat Generation at Stagnation Point
Authors: Ismail Nurul Syuhada , Mohd Shaipullah Norhunaini , Azhar Siti Aishah , Md Arifin Norihan , Ramli Norshafira , Mohamed Isa Siti Suzilliana Putri
Published: December 2024

Fluid dynamics encompasses the fundamental principles of continuity, momentum, and energy conservation, which are applied through mathematical models like the Navier-Stokes equations. These equations are essential for describing how fluid properties like velocity, pressure, and density change in response to forces and environmental conditions. Thus, this study attempted to explore the characteristics of flow and heat transfer of a shrinking sheet in magnetohydrodynamics (MHD), along with the effect of partial slip and heat generation on the system. We employ a similarity transformation technique for turning the governing partial differential equations into ordinary differential equations. These equations are solved numerically through shooting method in Maple, and the results are compared to the previous research. The analysis shows that the suction parameter and velocity slip parameter have an increasing effect on both the skin friction rate and the heat transfer rate. In the meantime, the heat transfer rate decreases as the parameter increases for the heat generation, magnetic parameter, Eckert number and thermal slip parameter. The bvp4c solver in MATLAB is implemented to conduct a stability analysis and determine the physically feasible solution. According to our research, the stability of the solution occurs only in the first solution.
PENDAMPINGAN UNTUK MENGATASI PROBLEMATIKA DALAM MENDAMPINGI ANAK BERKEBUTUHAN KHUSUS
Authors: Meka Marsianus , Wela Herkuliana Natalia , Dhiu Viktoria
Published: December 2024

Pengabdian merupakan salah satu bentuk Tridharma Perguruan Tinggi. Pengabdian yang dilakukan dalam kegiatan ini berjudul “Pendampingan Untuk Mengatasi Problematika Dalam Mendampingi Anak Berkebutuhan Khusus”. Tujuan dari kegiatan ini adalah untuk membantu bapak dan ibu guru untuk mengatasi problematika dalam membimbing anak berkebutuhan khusus. Metode yang di gunakan dalam kegiatan ini adalah metode pendampingan sebagai implementsi mata kuliah Pendidikan dan Permasalahan Anak Berkebutuhan Khusus. Teknik pengumpulan data yaitu melalui observasi dan wawancara dengan tujuan untuk mengimplementasi mata kuliah ABK. Hasil dari kegiatan ini ada tiga tahap yang dilakukan yaitu: tahap perencanaan, tahap pelaksanaan, dan taahp penilaian/evaluasi. Masalah dalam kegiatan pendampingan problematika ini adalah guru dapat merancang RPP, guru  dapat mengembangkan metode pembelajaran yang digunakan, anak berkebutuhan  kuhusus sulit di atur dan sarana prasarana perlu diperhatikan guna meningkatkan kemudahan bagi guru  dalam menghadapi anak ABK.
Recomendaciones para el mes de Noviembre
Authors:   Centro Nacional de Investigaciones de Café
Published: December 2024

La ocurrencia de lluvias durante noviembre y diciembre, no indica la finalización del Fenómeno de El Niño.
Recomendaciones para el mes de Enero
Authors:   Centro Nacional de Investigaciones de Café
Published: December 2024

Condiciones meteorológicas extremas han incidido en el comportamiento de las lluvias en todo el país. La zona cafetera tendrá una temporada seca más acentuada de lo normal.
Atlas Cafetero de Colombia
Authors:   Federación Nacional de Cafeteros de Colombia
Published: December 2024

El atlas cafetero de Colombia, elaborado con base en las estadísticas obtenidas en el Censo, se divide en dos partes principales: la primera, describe someramente el medio físico en donde las investigaciones se llevaron a cabo, las metodologías utilizadas y los preparativos necesarios, breves descripciones de las etapas de cómo se desarrollaron los estudios, la presencia y corrección errores cometidos y la descripción de algunas de las principales aplicaciones prácticas que pueden tener este tipo de estudios del medio; la segunda parte del atlas consiste en una serie de planchas, a grandes escalas, de varias de las principales regiones cafeteras del país.
Dalam ANALYSIS OF ISSUES AND PROBLEMS OF REGIONAL ECONOMIC DEVELOPMENT IN KUDUS DISTRICT
Authors: Alfaris Muh Rafi
Published: December 2024

In Indonesia's economic development, there are several issues and challenges that need to be addressed to achieve the desired progress. The following paper will explore in more depth the issues and problems of economic development that occur in Kudus Regency. The study conducted in this research uses the literature research method. The results of this research explain that first, national development aims to improve welfare and build a developed country with community participation and government support. However, development failures often stem from structural problems that require comprehensive solutions. Second, economic development in Kudus Regency is influenced by the Covid-19 Pandemic, SDGs, global economic crisis, environmentally friendly economy, natural disasters, and green space control. Third, the solution to improving economic development in Kudus Regency involves granting special autonomy to the regions. Economic diversification, job training, infrastructure improvement, innovation, and transparency in development policies are the key steps to achieve the goal.
Ambivalence as agency in Camille Reynaud’s
Et par endroits ça fait des nœuds
(2021)
Authors: Jordan Shirley
Published: December 2024

This article examines ambivalence and agency in contemporary life writing through focusing on an autopathography which highlights these features of self-narrative in original ways while also holding them in unusual tension. Camille Reynaud’s first publication,
Et par endroits ça fait des nœuds
(2021), addresses the abrupt loss of selfhood resulting from a ruptured cerebral aneurysm she experienced four years prior to publication. It draws the reader not only into a clinical reconstruction of trauma and treatment but also into the warp and weft of Reynaud’s ongoing, uneven attempt to re-establish agency and a stable sense of self. This article examines how the text, and the emerging sense of selfhood that it helps to produce, are shaped by medical imperatives, by voracious intertextual interlacing, and by the ways in which the author thinks with photography. It also asks how the premise of her book inflects important questions in life writing such as the tension between self-knowledge and self-invention, and the ways in which the self is socially constructed, understood, and talked about. Finally, it argues that
Et par endroits ça fait des nœuds
offers a newly ambivalent approach to life-writing’s emphasis on the body, embodiment, and corporeal experience through its focus on the body’s secret life and on the brain as locus of the self. The argument is underpinned with reference to the phenomenology of illness as theorized by Havi Carel, and Catherine Malabou’s ideas of post-traumatic subjectivity.
Glissement générique et ambivalence dans
Le consentement
(2020) de Vanessa Springora
Authors: Versini Dominique Carlini
Published: December 2024

Cet article se penchera sur la question de l’ambivalence dans
Le consentement
(2020) de Vanessa Springora. L’ambivalence sera envisagée selon le prisme du genre littéraire et, en particulier, de l’incursion dans le conte de fées. En effet, bien qu’il s’agisse d’un récit de vie qui prend la forme d’un témoignage réaliste, l’emprunt au conte ponctue le texte et est signalé dès son ouverture. L’étude démontrera dans un premier temps en quoi le genre du conte est pertinent pour penser l’ambivalence. Puis, l’article considérera l’emprunt au genre à travers deux axes d’analyse principaux : la figure de la mère et l’exploration de la relation entre la narratrice et « l’ogre ». L’analyse de cette relation permettra de considérer l’ambivalence du rôle de l’écriture perçue comme partie intégrante de la prédation que subit la narratrice. L’autre interrogation centrale du récit sera ainsi explorée : celle du rôle de la littérature. Cette analyse démontrera que le récit adopte une position ambivalente face à la littérature, entre attirance/admiration et méfiance, lieu de réalisation et de trahison. Elle soulignera que le projet littéraire de Springora va au-delà du simple témoignage et s’inscrit dans une longue lignée littéraire qui va du conte de fées à la littérature d’inceste contemporaine. En guise de conclusion, l’article proposera une réflexion sur l’ambivalence de la libération de la parole autour des violences sexuelles à la lumière de la réception du
Consentement
.
Import dependence of the European organic market and the role of Ukrainian exports
Authors: Nifatova Olena , Danko Yuriy , Petrychuk Svitlana , Baležentis Tomas , Štreimikienė Dalia
Published: December 2024

The European market for organic products has been expanding, with a persistent difference between the growth rates of organic retail trade (actual demand for organic products) and the growth rates of organic agricultural land areas (potential supply of organic products). This makes the European Union (EU) dependent on global imports. This research focuses on the import of organic products from Ukraine. To understand the underlying factors of the EU-27 countries’ import dependence on Ukrainian exports, this article proposes the following: 1) an analysis of Ukraine’s contribution to the total import volume to EU-27 countries by categories of organic products that have the most significant share in overall imports from Ukraine (these categories include: cereals, other than wheat and rice; soybeans; wheat; oilseeds, other than soybeans); 2) a study of the general trends of the European organic market’s import dependence on imports from Ukraine by the categories with the highest contribution; 3) clustering of the EU-27 countries based on organic market indicators; 4) an analysis of the European organic market using Ukrainian imports as an example. Ukrainian imports do not threaten the domestic European market; instead, countries with the highest level of dependence can use Ukrainian organic raw materials for processing and further re-export.
frb-voe: A Real-time Virtual Observatory Event Alert Service for Fast Radio Bursts
Authors: Abbott Thomas C. , Zwaniga Andrew V. , Brar Charanjot , Kaspi Victoria M. , Petroff Emily , Bhardwaj Mohit , Boyle P. J. , Cook Amanda M. , Joseph Ronniy C. , Masui Kiyoshi W. , Pandhi Ayush , Pleunis Ziggy , Scholz Paul , Shin Kaitlyn , Tendulkar Shriharsh
Published: December 2024

We present frb-voe, a publicly available software package that enables radio observatories to broadcast fast radio burst (FRB) alerts to subscribers through low-latency virtual observatory events (VOEvents). We describe a use case of frb-voe by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst (CHIME/FRB) Collaboration, which has broadcast thousands of FRB alerts to subscribers worldwide. Using this service, observers have daily opportunities to conduct rapid multiwavelength follow-up observations of new FRB sources. Alerts are distributed as machine-readable reports and as emails containing FRB metadata, and are available to the public within approximately 13 s of detection. A sortable database and a downloadable JSON file containing FRB metadata from all broadcast alerts can be found on CHIME/FRB’s public webpage. The frb-voe service also provides users with the ability to retrieve FRB names from the Transient Name Server through the frb-voe client user interface. The frb-voe service can act as a foundation on which any observatory that detects FRBs can build its own VOEvent broadcasting service to contribute to the coordinated multiwavelength follow-up of astrophysical transients.
Enhanced Peak and Extended Cooling of the Extreme-ultraviolet Late Phase in a Confined Solar Flare
Authors: Li Shihan , Dai Yu , Ding Mingde , Li Zhen , Guo Jinhan , Wu Hao
Published: December 2024

We present observations and analysis of an X1.8 noneruptive solar flare on 2012 October 23, which is characterized by an extremely large late-phase peak seen in the warm coronal extreme-ultraviolet (EUV) emissions (∼3 MK), with the peak intensity over 1.4 times that of the main flare peak. The flare is driven by a failed eruption of a magnetic flux rope, whose strong squeeze force acting on the overlying magnetic structures gives rise to an intense early heating of the late-phase loops. Based on differential emission measure analysis, it is found that the late-phase loops experience a “longer-than-expected” cooling, without the presence of any obvious additional heating, while their volume emission measure maintains a plateau for a long time before turning into an evident decay. Without the need for an additional heating, we propose that the special thermodynamic evolution of the late-phase loops revealed in this flare might arise from loop cross-sectional expansions with height, which are evidenced by both direct measurements from EUV images and by magnetic field extrapolation. By blocking the losses of both heat flux and mass from the corona, such an upward cross-sectional expansion not only elongates the loop-cooling time, but also more effectively sustains the loop density, therefore leading to a later-than-expected occurrence of the warm coronal late phase in combination with a sufficiently high late-phase peak. We further verify such a scenario by analytically solving the cooling process of a late-phase loop characterized by a variable cross section.
The Redshift of GRB 190829A/SN 2019oyw: A Case Study of GRB-SN Evolution
Authors: Bhirombhakdi Kornpob , Fruchter Andrew S. , Levan Andrew J. , Pian Elena , Mazzali Paolo , Izzo Luca , Kangas Tuomas , Benetti Stefano , Medler Kyle , Tanvir Nial
Published: December 2024

The nearby long gamma-ray burst (GRB) 190829A was observed using the Hubble Space Telescope/Wide Field Camera 3/infrared grisms about four weeks to 500 days after the burst. We find the spectral features of its associated supernova, SN 2019oyw, are redshifted by several thousand km s−1 compared to the redshift of the large spiral galaxy on which it is superposed. This velocity offset is seen in several features but most clearly in Ca ii near-infrared triplet λλ8498, 8542, 8662 (CaIR3). We also analyze Very Large Telescope/FOcal Reducer and low dispersion Spectrograph and X-shooter spectra of the supernova (SN) and find strong evolution with time of its P-Cygni features of CaIR3 from the blue to the red. However, comparison with a large sample of Type Ic-BL and Ic SNe shows no other object with the CaIR3 line as red as that of SN 2019oyw were it at the z = 0.0785 redshift of the disk galaxy. This implies that SN 2019oyw is either a highly unusual SN or is moving rapidly with respect to its apparent host. Indeed, using CaIR3 we find the redshift of SN 2019oyw is 0.0944 ≤ z ≤ 0.1156. The GRB-SN is superposed on a particularly dusty region of the massive spiral galaxy; therefore, while we see no sign of a small host galaxy behind the spiral, it could be obscured. Our work provides a surprising result on the origins of GRB 190829A, as well as insights into the time evolution of GRB-SNe spectra and a method for directly determining the redshift of a GRB-SN using the evolution of strong spectral features such as CaIR3.
A Precursor to Solar Prominence Eruptions: Detection and Analysis of EUV Prominence Oscillations
Authors: Beckwith-Chandler William , Foullon Claire , Verwichte Erwin
Published: December 2024

The eruption of prominences can have a significant influence on the solar–terrestrial environment. However, accurately predicting these eruptions remains a challenge. We apply automated detection methods for extreme ultraviolet (EUV) prominences observed by the twin spacecraft from the Solar Terrestrial Relations Observatory (STEREO) mission and the Solar Dynamics Observatory near Earth. We study an event, during 2011 March, when each STEREO spacecraft is in quadrature with respect to the Earth. For two time ranges, we obtain longitudinal height profiles as a function of time. We also track the corresponding EUV filaments across the solar disk, which reveal the emergence of ultra-long-period oscillations in the EUV filament channels. Our analysis shows a correlation between the prominence’s increasing height and the oscillation periods, suggesting a potential link to the subsequent eruption observed by the STEREO spacecraft off-limb. These findings offer new insights into prominence dynamics and may pave the way for improved eruption prediction.
Molecular Gas Mass Measurements of an Active, Starburst Galaxy at z ≈ 2.6 Using ALMA Observations of the [C i], CO, and Dust Emission
Authors: Huang Hao-Tse , Man Allison W. S. , Lelli Federico , De Breuck Carlos , Ghodsi Laya , Zhang Zhi-Yu , Lin Lingrui , Zhou Jing , Bisbas Thomas G. , Nesvadba Nicole P. H.
Published: December 2024

We present new Atacama Large Millimeter/submillimeter Array (ALMA) observations of a starburst galaxy at cosmic noon hosting a radio-loud active galactic nucleus: PKS 0529-549 at z = 2.57. To investigate the conditions of its cold interstellar medium, we use ALMA observations that spatially resolve the [C i] fine-structure lines, [C i] (2–1) and [C i] (1–0), CO rotational lines, CO (7–6) and CO (4–3), and the rest-frame continuum emission at 461 and 809 GHz. The four emission lines display different morphologies, suggesting spatial variation in the gas excitation conditions. The radio jets have just broken out of the molecular gas but not through the more extended ionized gas halo. The [C i] (2–1) emission is more extended (≈8 kpc × 5 kpc) than detected in previous shallower ALMA observations. The [C i] luminosity ratio implies an excitation temperature of 44 ± 16 K, similar to the dust temperature. Using the [C i] lines, CO (4–3), and 227 GHz dust continuum, we infer the mass of molecular gas M
mol using three independent approaches and typical assumptions in the literature. All approaches point to a massive molecular gas reservoir of about 1011
M
☉, but the exact values differ by up to a factor of 4. Deep observations are critical in correctly characterizing the distribution of cold gas in high-redshift galaxies, and highlight the need to improve systematic uncertainties in inferring accurate molecular gas masses.
On the Possible Mechanisms of the SEP Event and Electron Enhancement over the SEP Decay Phase on 2023 August 5
Authors: Firoz Kazi A. , Li Y. P. , Gan W. Q.
Published: December 2024

We carry out this study on the solar energetic particle (SEP) event that occurred on 2023 August 5 over the ascending phase of the current solar cycle 25. It is found that the SEP event might have been initiated by the M1.6 flare, while the SEP peak was caused by the coronal shock manifested in DH-type II radio burst over the propagation phase of a halo coronal mass ejection (CME; ∼1000 km s−1), thus creating a mixed SEP event. There were two enhancements of the electron fluxes lying over the SEP rise and decay phase. It is surprising that, despite a stronger flare (X1.6) and a faster halo CME (∼1647 km s−1), there was no SEP enhancement during the second enhancement of the electron fluxes. In order to investigate this, we make an additional effort to analyze the X1.6 flare based on the availability of the temporal, spectral, and spatial evolution of the electromagnetic radiation components. It is observed that the CME shock was aligned with the flare eruption direction and was close to the western limb (W77°), and thus the radially moving CME shock missed the Earth. In another development, it is observed that the electron impulsive phase lies over the type III radio bursts, indicating that the electrons might have escaped directly during the eruption. The radio flux and radio dynamic spectra of a higher frequency lie over the rise phase of the soft X-ray derivative, indicating that a large number of electrons travelled through magnetic fields.
SCExAO/CHARIS Spectroscopic Characterization of Cloudy L/T Transition Companion Brown Dwarf HIP 93398 B
Authors: Lewis Briley L. , Li Yiting , Gibbs Aidan , Fitzgerald Michael P. , Brandt Timothy , Bardalez Gagliuffi Daniella , An Qier , Chen Minghan , Bowens-Rubin Rachel , Salama Maïssa , Lozi Julien , Jensen-Clem Rebecca , Mazin Ben
Published: December 2024

Brown dwarfs with measured dynamical masses and spectra from direct imaging are benchmarks that anchor substellar atmosphere cooling and evolution models. We present Subaru SCExAO/CHARIS infrared spectroscopy of HIP 93398 B, a brown dwarf companion recently discovered by Y. Li et al. (2023), as part of an informed survey using the Hipparcos–Gaia Catalog of Accelerations. This object was previously classified as a T6 dwarf based on its luminosity, with its independently derived age and dynamical mass in tension with existing models of brown dwarf evolution. Spectral typing via empirical standard spectra, temperatures derived by fitting substellar atmosphere models, and J − H, J − K and

H
−
L
′

colors all suggest that this object has a substantially higher temperature and luminosity, consistent with classification as a late-L dwarf near the L/T transition (T =

1200

−
119

+
140

K) with moderate to thick clouds possibly present in its atmosphere. When compared with the latest generation of evolution models that account for clouds with our revised luminosity and temperature for the object, the tension between the model-independent mass/age and model predictions is resolved.