bluuebunny/crossref_metadata_2025 huggingface dataset:
Drinking water quality and associated factors in Bahir Dar City and the surrounding rural areas, Northwest Ethiopia: a community-based cross-sectional study
Authors: Sitotaw Baye , Teferi Derebew , Wossen Zinash , Tadesse Beselam
Published: August 2023

In low-income countries like Ethiopia, waterborne illnesses have posed serious public health problems. This study aimed to evaluate drinking water quality (DWQ) and associated factors in Bahir Dar City and the surrounding rural areas in northwest Ethiopia. A cross-sectional study was conducted from January to June 2022 to determine coliform counts and basic physicochemical parameters from the drinking water samples (DWS) collected from urban, peri-urban, and rural sites. A total of 180 DWS were collected from water collection points and households' containers. Potentially pathogenic bacteria were also isolated from fecal coliform (FC)-positive samples and their antibiotic susceptibility profiles were determined. Moreover, the risk factors associated with water quality were assessed. The water quality test results were evaluated against the WHO guidelines for DWQ. Based on the results of this study, only 16.7 and 73.88% of samples met the standards for total coliform and FC, respectively. Moreover, 95.4 and 43% of the isolated bacteria were resistant at least to one of the commonly used antibiotics and multidrug-resistant, respectively. Educating the public on proper drinking water handling, appropriate treatment, and waterline maintenance are needed to safeguard the community from waterborne diseases.
Narrativas de artesanato e autenticidade na formação do mercado de cerveja artesanal no Brasil
Authors: Felipe Sgorla Andrey
Published: August 2023

O crescimento do mercado de cerveja artesanal envolve uma série de atrativos para produtores e consumidores, incluindo um alto grau de autonomia, paixão e trabalho como hobby em pequenas empresas, onde os cervejeiros usam “conhecimento intuitivo”, bem como flexibilidade de tempo para fazer cervejas artesanais. Como produtos artesanais, as cervejas artesanais têm sido associadas a marcadores de identidade e noções de “autenticidade”, com uma gama de atributos econômicos e culturais. O estudo se utiliza de entrevistas em profundidade, observação participante em visitas a cervejarias e participação em festivais e acompanhamento de publicações nas redes sociais. No artigo, exploramos como as narrativas dos microcervejeiros brasileiros sobre artesanato e autenticidade são utilizadas como dispositivos de mercado para legitimar seus produtos, ganhando reconhecimento dentro do mercado e construindo relações de consumo no contexto do novo espírito do capitalismo. As estratégias de narração não apenas “enriquecem” o produto; elas também incentivam os indivíduos a localizar o prazer por meio do trabalho e a perceber o valor em termos de identidade e estilo de vida, em vez de termos monetários.
VIABILIDAD DE PAGOS POR SERVICIOS ECOSISTÉMICOS PROVEÍDOS POR EL REFUGIO DE VIDA SILVESTRE LAQUIPAMPA, LAMBAYEQUE – PERÚ
Authors: Mercado Waldemar , Minaya Carlos , Tovar Luis Antonio
Published: August 2023

Las áreas naturales protegidas y los pagos por servicios ambientales son mecanismos de conservación que lideran las políticas ambientales a nivel mundial. Por ello, los formuladores de políticas se enfrentan a la elección de la efectividad de los mecanismos de conservación y su evaluación sobre cómo lograrlo sin comprometer el bienestar de las poblaciones que viven dentro de esos territorios. El objetivo del estudio fue evaluar la viabilidad de implementar mecanismos de retribución por servicios ecosistémicos en el Refugio de Vida Silvestre Laquipampa. La metodología comprendió la identificación, evaluación y valoración económica de los servicios ecosistémicos priorizados, de acuerdo a tres criterios: contribución a la economía local, disponibilidad de información para efectuar la valoración económica y la plausibilidad de implementar actividades respecto de los objetivos del Plan Maestro. Los resultados señalan que existe la posibilidad de implementar retribución por servicios ecosistémicos en la provisión de vainas de tara (Caesalpinea spinosa) y en servicios turísticos de recreación asociados al hábitat de la pava aliblanca (Penelope albipennis). Así, se estimó que el valor económico total que generan estos servicios ecosistémicos asciende a USD 12 389 anuales y se evidencia que es posible viabilizar los mecanismos de retribución por servicios ecosistémicos en áreas naturales protegidas siempre que exista una significativa población de retribuyentes y que la provisión de bienes sea reconocida por el mercado.
ANÁLISIS TEMPORAL DE LOS CONTAMINANTES ATMOSFÉRICOS (NO2, O3 TROPOSFÉRICO Y CO) Y SU RELACIÓN CON LA TEMPERATURA DEL AIRE Y LA RADIACIÓN SOLAR EN LIMA METROPOLITANA
Authors: Benites-Morales Orlando Fernando , Pacsi-Valdivia Sergio Artemio
Published: August 2023

El presente estudio comprende el análisis temporal de los niveles de NO2, CO y O3 troposférico acontecidos en Lima Metropolitana entre los años 2015 al 2018, y su relación entre sí y con la temperatura del aire y la radiación solar. Para ello, se desarrollaron análisis temporales descriptivos, correlacionales y de regresión empleando información horaria registrada en diferentes zonas que componen la ciudad. Se advirtió que los niveles de los gases evaluados se encontraron principalmente por debajo de la normativa peruana y los valores guía establecidos por la Organización Mundial de la Salud, por lo que su influencia en la salud de la población no fue relevante. El comportamiento horario de estos gases fue bimodal y estuvo influenciado por el tráfico vehicular para el NO2 y el CO, y por la radiación solar para el O3 troposférico; aunque, posiblemente este último también haya estado influenciado por su desplazamiento nocturno. En el comportamiento diario se evidenció el denominado “efecto fin de semana”. El análisis correlacional indicó un comportamiento homogéneo de los parámetros entre las zonas evaluadas; y se observó una clara correlación negativa entre el CO con el O3 troposférico y una clara correlación positiva entre el NO2 con el CO y entre los parámetros meteorológicos con el NO2 y con el O3 troposférico. Finalmente, se generaron modelos de regresión lineal múltiple que estimaron adecuadamente los valores históricos de O3 troposférico.
The Prevalence of HLA-B*57 Serotype Associated with Hypersensitivity Reactions in the Treatment of HIV İnfection in the Turkish Population
Authors: Kizmaz Muhammed Ali , Simsek Abdurrahman , Aymak Figen , Akalin Emin Halis , Oral Haluk Barbaros , Budak Ferah
Published: August 2023

Objectives:

The aim of our study is to reveal the prevalence of HLA-B*57 in the Turkish
population and to provide new perspectives to physicians starting abacavir therapy in HIV patients.

Background:

Abacavir, one of the drugs used to treat HIV infection, can cause hypersensitivity reactions
in some patients. These hypersensitivity reactions have been shown to be associated with the
HLA-B*57:01 allele. High-resolution HLA-B*57:01 scanning has a time and cost disadvantage
compared with low-resolution HLA-B*57 scanning. Before starting abacavir treatment, we will discuss
whether high-resolution scanning is more beneficial in individuals who are positive on HLAB*
57 screening. This is the study with the largest cohort to investigate the prevalence of HLA-B*57
in Turkey.

Methods:

The results of 25 thousand 318 people who applied to Bursa Uludağ University Faculty of
Medicine, Department of Immunology for HLA-B* typing were scanned.

Results:

In our study, the HLA-B*57 serotype was detected in 827 (3.3%) individuals.

Conclusion:

Considering these results, it can be assumed that the prevalence of HLA-B*57:01 in
Turkey is lower than 3.3%. Instead of a high-resolution HLA-B*57:01 scan in all patients starting
abacavir therapy, a high-resolution HLA-B*57:01 scan might be of greater benefit in patients who
are positive on a low-resolution HLA-B*57 scan.
Recent Advances in Total Synthesis of Tetrahydroisoquinoline Alkaloids
Quinocarcin and Lemonomycin
Authors: Guo Ju , Yang Yang , Shen Lanhua , Li Jingyi , Li Fuan , Wang Sifan
Published: August 2023

Tetrahydroisoquinoline natural products are a kind of alkaloids containing various
pharmacological activities. These structurally diverse alkaloids mainly consist of two subclasses,
monotetrahydroisoquinolines (MTHI) and bistetrahydroisoquinolines (BTHI). Since its family
member, Ecteinascidin-743 (INN: Trabectedin, trade name: Yondelis®), has been approved by
European Union in 2007 and the FDA in 2015 for the treatment of advanced soft tissue tumors, the
research on this kind of natural product is full of new vitality. Quinocarcin and lemonomycin share a
common diazabicyclo[3.2.1]octane framework that belongs to the subclass of MTHI, and their excellent
antitumor activity and challenging architecture have made them an ideal target for total synthesis.
In this short review, the progress in the total synthesis of quinocarcin and lemonomycin is summarized.
The Clinical Effectiveness of Transcutaneous Electrical Nerve Stimulation
on Enhancing Recovery after Cesarean Section: A Systematic Review and
Meta-Analysis
Authors: Albadrani Muayad Saud , Elhusein Amal Mohamed , Ali Fadlalmola Hammad , Mohamed Osman Abdalla , Hosean  Balola Hamza , Elsayed Ebrahim Elturabi , Saud Albadrani Muhannad , Saad Mohammed Amira Mohamed , Hamouda Babiker Sitelgeel , Miskeen Elhadi , Elnour Suaad , Yousif Elhussain Mariam
Published: August 2023

Background:

The transcutaneous electrical nerve stimulation TENS was used following several surgical procedures involving gynecological ones and has shown a successful pain reduction rate. TENS was proposed to enhance recovery after cesarean section CS.

Objective:

This systematic review and meta-analysis were conducted to evaluate the clinical effectiveness of Transcutaneous electrical nerve stimulation TENS in enhancing recovery after a cesarean section.

Methods:

We performed the Meta-analyses using RevMan software. Data were pooled as mean difference (MD) if continuous and risk ratio (RR) if dichotomous, and the 95% confidence interval (CI) as calculated.

Results:

This systematic review included 12 RCTs, with a total of 1,116 women studied. The TENS effectively reduced the intensity of pain just by following its application (SMD=-0.61; 95% CI [-0.82, -0.39], P<0.00001), one day after (SMD=-0.25; 95% CI [-0.47, -0.04], P=0.02), and two days after (SMD=-0.27; 95% CI [-0.50, -0.03], P=0.03).

Conclusion:

The TENS effectively reduces the pain intensity following its application and after one or two days. TENS has no effect on the cumulative dose of diclofenac. Because of the inadequacy of safety data, we recommend conducting further RCTs.
Thermal Instability of Commercial Dual-axis MEMS Accelerometers
Authors: Łuczak Sergiusz , Zams Maciej , Pieńczuk Paweł
Published: August 2023

Introduction:

Thermal drifts of MEMS sensors are one of their biggest shortcomings.
However, experimental studies may offer a solution while striving for the reduction of related errors.

Objective:

The aim was to determine the thermal drifts of MEMS accelerometers associated with the
offset voltage and the scale factor and then to propose a way of reducing the resultant errors.

Methods:

Four commercial dual-axis MEMS accelerometers (two pieces of ADXL 202E and two
pieces of ADXL 203 by Analog Devices Inc.) with analog outputs were experimentally tested with respect
to their thermal instability, employing two computer-controlled test rigs that provided a stable
orientation of the accelerometers.

Results:

It was found that the thermal drifts of the offset voltage generated by the tested accelerometers
were considerable, resulting in respective errors of about 14 mg (ADXL 202E) or 7 mg (ADXL
203), whereas catalog values of drifts of the scale factor were much lower.

Conclusion:

The determined values are smaller than their counterparts specified in the relevant manufacturer
datasheets; significant differences exist between the tested pieces of the two accelerometers
(40% or 78%) as well as between the two sensitive axes of a single accelerometer (84% or 80%), this
can be taken into consideration while striving for a higher accuracy of an acceleration measurement.
In silico Exploration of Bioactive Compounds from Withania somnifera as Inhibitor for Alpha Delta Bungarotoxin of Bungarus candidus Venom
Authors: Prabasari Kartika , Kurnianingsih Nia , Kurniawan Nia
Published: August 2023

The antivenom for Malayan krait (Bungarus candidus) venom has not yet been available in Indonesia, leading to many fatal snakebite cases. Alternative treatment approaches using medicinal plants are needed to be explored. This study investigated the potential of medicinal plants natural bioactive compounds as toxic alpha-delta protein bungarotoxin inhibitor in B. candidus venom. The approach taken is using the 3D structure of the alpha-delta protein of bungarotoxin B. candidus predicted by SWISS-MODEL. Knapsack Family Database and PubChem were used for bioactive compounds datamining.
On the Inverse of a Square Matrix Using Logarithm
Authors: Rellon Louie Resti
Published: August 2023

Assume that Ais an nnmatrix with real numbers as entries and the determinant of A≠ 0. In this study, we established the results of getting the inverse of a matrixA using thelogarithmic methodand used some examples to discuss the necessity of getting the inverse of a matrix using the logarithm for both positive and negative determinants in terms of a given determinant of a matrix A. If the det A > 0, we have()1Alog det Aadj A−=, where =detAdetA. However, if the det A < 0, we have()1detAAadjAlog−=−, wheredetdetAA=.
Analisis Kinerja Struktur Gedung Bertingkat Menggunakan Sistem Rangka Pemikul Momen Khusus (SRPMK) pada Pembangunan Rumah Susun Cakung Jakarta Timur
Authors:   Universitas Jember, Dewi Hesty Auliya , Widayanto Erno ,   Universitas Jember, Wiswamitra Ketut Aswatama ,   Universitas Jember
Published: August 2023

Analysis of the structural performance of the Cakung house in East Jakarta aims to determine the behavior and performance of the building by using the Special Moment Bearing Frame system (SRPMK). Evaluation is carried out on the performance of the building structure by using a structural analysis aid program. And the lateral force capacity that the system can withstand is 1592432.05 Kgf in the X direction and 643948.61 Kgf in the Y direction. Where the pushover analysis using the ATC 40 method, the melting point occurred for the first time at a displacement of 23.57 cm in the X direction and 7.28 cm in the Y direction. And serious damage occurred at the displacement of 77.49 cm in the X direction and 94.84 in the Y direction. The analysis found that the drift ratio value of the maximum total deviation and the maximum inelastic deviation that occurs in the structure is less than 1%. So that the level of performance of the design is in the category of Immediate Occupancy (IO).
Evaluasi Perilaku dan Kinerja Struktur Gedung Pelayanan Medis Rumah Sakit RKZ Surabaya Dengan SNI 1726:2019
Authors:   Institut Teknologi Adhi Tama, Istiono Heri , Dzakwan Madaret Rifqi ,   Institut Teknologi Adhi Tama
Published: August 2023

Updating regulations from SNI 1726 – 2012 to SNI 1726 – 2019 allows evaluation of the behavior and performance of building structures to reduce the risks posed by earthquakes. This is necessary because in SNI 1726-2019 there is an additional long period in the spectrum response so it is necessary to evaluate it to ensure that the building structure whose behavior still meets the requirements in the regulation. The method used in this study was the pushover analysis method. This study evaluates the St. Catholic Hospital Medical Services building. Vincent a. Paul (RKZ) Surabaya. This study discusses building analysis based on SNI 1726 - 2019 to determine the behavior and performance of structures. The results of this study indicate that the behavior of the structure which includes the time period, base shear force, drift ratio, dual system control meets the requirements in accordance with SNI 1726-2019. This performance level is included in the LS (Life Safety) category.
Linkage among Two Satellite Cities: What makes People Move? (Case study: Bogor Regency and Depok City)
Authors: Wijayanti Wawargita , Mahmud Sulthon , Subagiyo Aris
Published: August 2023

An interaction between cities around metropolitan system occurs due to the limitless of infrastructures, demand of goods-jobs, and others. This case occurs in Bogor Regency and Depok City, as secondary or satellite cities of Jabodetabekpunjur Area. Exchanges of people, goods, and infrastructures among those areas show essential elements of linkages, reflecting three of seven types of linkages. This research examines the factors that influence the linkage among Bogor Regency and Depok City. Besides, it also comprises a relationship between those influential factors and reason of each interaction. We used a factor analysis and cross-tabulation technique to answer those two research objectives. The results show that time, road, consumption and expenditure pattern, regular needs, and use of facilities are crucial factors influencing interaction among the areas. In addition, analysis also reflect that there is a high connection among distance and income to the linkages of the cities. With these findings, this research would contribute not only to enrich on-going discussion related to types of interaction among cities in metropolitan area, but also give empirical evidence about how the balance interaction among cities, which underlines sustainability of regional system occurs.
The Economic Conditions of a 3D Tourism Village in the Application of Pro-poor Tourism and Social Capital
Authors: Putri Ike , Sari Nindya , Fikriyah  , Hiddlestone-Mumford Jacqueline , Illingworth Juanita , Vieira Thiago
Published: August 2023

Kesatrian Village has received global attention for successfully changing the image of the slum area into one of the must-visit tourist destinations in Malang City. The application of the Pro-Poor Tourism (PPT) concept to create Kampung Tridi saw village residents participate in tourism activities. This study examines the relationship between social capital and PPT tourism activities on poverty conditions. The analytical methods applied in this study include social network analysis (SNA) and descriptive analysis. PPT activities positively affect all aspects of people's lives. First, better community social capital is assumed to lead to better tourism management. Second, the relationship between social capital and tourism is directly proportional to the community's economic condition, in which more social capital generates better tourism activities, thereby reducing poverty in Kampung Tridi.
Methodological aspects of optimization of energy consump-tion costs of low-rise buildings with a built-in air heat pump
Authors: Krupnov E. I. , Zaitseva I. A. , Loginova S. A. , Zaitsev I. S.
Published: August 2023

Objective. The rational use of fuel and energy resources is one of the urgent problems. One of the promising ways to solve this problem is the use of environmentally friendly energy-saving air source heat pumps based on the use of non-traditional energy sources. The use of such innovative energy-saving technologies requires not only modern architectural and planning, design and engineering solutions, but also sound methodological recommendations for as-sessing their energy efficiency and feasibility. The article presents a methodology for calculating the consumed electrical energy and heat generation, as well as the seasonal indicator of energy efficiency in the operation of an air source heat pump.Method. The technique takes into account, as input data, experimental data from tests of high-voltage heat pumps in terms of heat output depending on the change in the temperature of the source of low-grade heat and the temperature regime of the coolant.Result. The need to develop a methodology is due to the shortcomings in the regulatory documents of the methodological basis for optimizing energy costs and heat generation by heat pumps. The accuracy of calculating the operating costs that will occur during the heating period of the air source heat pump (AHP) depends on the correct accounting of the required heat load of a low-rise building and the consumption of electricity to ensure it.Conclusion. This technique can be applied not only to calculate the annual operating costs of using a heat pump and determine the structure of energy consumption (thermal and electrical), but also to optimize the energy parameters of HHP with an assessment of the energy efficiency of different options for their configurations.
From the Cochrane Library: Leukotriene Receptor Antagonists for Eczema (Preprint)
Authors: Toledo Lauren Marie , Rodriguez Ramiro , Sivesind Torunn E , Vakirlis Efstratios , Kojima Reiji , Dellavalle Robert P
Published: August 2023

UNSTRUCTURED
Generative Language Models and Open Notes: Exploring the Promise and Limitations (Preprint)
Authors: Blease Charlotte , Torous John , McMillan Brian , Hägglund Maria , Mandl Kenneth D
Published: August 2023

UNSTRUCTURED

Patients’ online record access (ORA) is growing worldwide. In some countries, including the United States and Sweden, access is advanced with patients obtaining rapid access to their full records on the web including laboratory and test results, lists of prescribed medications, vaccinations, and even the very narrative reports written by clinicians (the latter, commonly referred to as “open notes”). In the United States, patient’s ORA is also available in a downloadable form for use with other apps. While survey studies have shown that some patients report many benefits from ORA, there remain challenges with implementation around writing clinical documentation that patients may now read. With ORA, the functionality of the record is evolving; it is no longer only an aide memoire for doctors but also a communication tool for patients. Studies suggest that clinicians are changing how they write documentation, inviting worries about accuracy and completeness. Other concerns include work burdens; while few objective studies have examined the impact of ORA on workload, some research suggests that clinicians are spending more time writing notes and answering queries related to patients’ records. Aimed at addressing some of these concerns, clinician and patient education strategies have been proposed. In this viewpoint paper, we explore these approaches and suggest another longer-term strategy: the use of generative artificial intelligence (AI) to support clinicians in documenting narrative summaries that patients will find easier to understand. Applied to narrative clinical documentation, we suggest that such approaches may significantly help preserve the accuracy of notes, strengthen writing clarity and signals of empathy and patient-centered care, and serve as a buffer against documentation work burdens. However, we also consider the current risks associated with existing generative AI. We emphasize that for this innovation to play a key role in ORA, the cocreation of clinical notes will be imperative. We also caution that clinicians will need to be supported in how to work alongside generative AI to optimize its considerable potential.
How College Students Used Information From Institutions of Higher Education in the United States During COVID-19: Web-Based Cross-Sectional Survey Study (Preprint)
Authors: Peprah Emmanuel , Amesimeku Etornam , Angulo Brian , Chhetri Himani , Fordjuoh Judy , Ruan Christina , Wang Cong , Patena John , Vieira Dorice , Ryan Nessa , Iloegbu Chukwuemeka , Gyamfi Joyce , Odumegwu Jonathan
Published: August 2023

BACKGROUND

The start of the COVID-19 pandemic resulted in the implementation of nonpharmaceutical interventions by US institutions of higher education at an unprecedented level. During the backdrop of an emerging pandemic, younger adults (eg, college students) had an overall lower risk for severe outcomes for SARS-CoV-2, making this population a potential source of transmission for age groups with high susceptibility and negative health outcomes. We examine how college students’ level of concern for COVID-19 was influenced by different sources of information, their living status, income level, and other demographic identifiers and its association with prevention behavior change.

OBJECTIVE

We sought to examine the level of concern, defined as the extent to which the participant would take corrective action to mitigate contracting or spreading the virus (to family or friends) by using personal protective equipment such as a face mask, practicing social distancing, and following other public health recommendations, among college students during the COVID-19 pandemic.

METHODS

A cross-sectional, web-based survey was conducted in 2021 among 185 college students aged 18-41 years, with most living in New York City and the United States (n=134, 72.4%). Out of 185 college students, 94 provided their zip codes, with 51 of those college students indicating they lived in New York City areas. The participants completed the survey via a QR code. Study participants who did not complete the full survey or were not college students in any US college or university were excluded. Analyses were conducted using R (version 4.2.2; R Foundation for Statistical Computing).

RESULTS

Of 185 respondents participated in the study, 25 (13.5.%) used emails from their schools, 51 (27.6%) used mainstream media, and 109 (58.9%) used social media and other sources to obtain information about COVID-19. Of the 109 participants who learned about the pandemic from social media, 91 (83.5%) were concerned; however, only 63% (32/51) and 60% (15/25) of the participants who sourced information from mainstream media and their schools’ email, respectively, were concerned. Further, the participants who received information from social media and other sources were about 3 times more likely to be concerned about COVID-19 than participants who received information from the university via email (P=.036; OR=3.07, 95% CI: 1.06-8.83)..

CONCLUSIONS

College students who received information from social media and other sources were more likely to be concerned about COVID-19 than students who received information from their school via emails.
Author Reply (Preprint)
Authors: Mathews Simon
Published: August 2023

UNSTRUCTURED

This is a response to the Letter to the Editor relating to our previously published manuscript, "Assessing the Clinical Robustness of Digital Health Startups: Cross-sectional Observational Analysis" https://www.jmir.org/2022/6/e37677/
Depiction of Caste Annihilation and Class Abrogation in Mulk Raj Anand’s UNTOUCHABLE and COOLIE
Authors: Bharadwaj Dr. Purnima , Dilkesh Mr.
Published: August 2023

Since civilization has started caste system based on profession not by birth. Later on it turns into a power game and the whole human society were divided into four varnas. Manusmriti, widely regarded to be the important and authoritative book on Hindu law and dating back to at least 1000 years before Christ was born ‘‘acknowledges and justifies the caste system as the basis of order and regularity of society .’’(Web ) The caste divides Hindu into four main categories – Brahmins, Kshatriyas, Vaishyas and Shudras. Many believe that the groups originated from Brahma , The Hindu God of Creation. They are classified according to occupation and determine access to wealth , power and privilege. In recent years Violence has become a common phenomenon in India. It has engulfed the entire political, social, economic, cultural and even our personal lives. Violence of social justice and caste discriminations of complex characters have added additional burden to our society whereas we Indians have been specially advised to practice “non-violence”. The growing trend in violence thus provokes us to talk about non-violence and identify the roots of violence in India. Caste Violence is perhaps one of the most hazardous forms of violence in India. It often intermingles with the most political, social, cultural, and class atrocity. So caste discriminations and atrocities against the socially weaker sections with age- old traditional and unconventional norms deserve a careful historical investigation. Indian Caste system is the most widely discussed subject all over the world. Caste system is a social evil in which the higher caste people exploits and persecutes the lower caste people and forced them to live sub-human lives like beasts. This paper is based on caste and vulgarism of ‘Untouchable’ and ‘Coolie’ poignantly portrayed by M R Anand. It is an attempt to explore its origin, nature, gravity, and deprivation.
Cultural and Religious Customs Representation of James Kirkpatrick in the Novel of White Mughals
Authors: Tembhurne Punyashil S.
Published: August 2023

Abstract: William Dalrymple is that rarity, a scholar of history who can really write. His White Mughals represent a full account of life and times of the 18th century court of Hyderabad. White Mughals is a historical love story of James Kirkpatrick and Khair un Nissa, she is the ‘Most Excellent Among Women’- in 1800, William Dalrymple’s James Achilles Kirkpatrick was a Lieutenant Colonel in The British Resident. Dalrymple represents Hyderabadi culture marriage ceremony, baptsim , way of eating and dinner in the court of Nizams of Hyderabad. The celebration of Hyderabadi religious festivals and customs in India shows the importance of Indian Hyderabadi culture
Comparative Evaluation of Risk Adjustment Techniques for Provider Profiling: A Propensity Score Analysis
Authors: Shah Wasim Fathima
Published: August 2023

Abstract: Background: Profiling health care providers requires proper adjustment for case-mix. However, traditional risk adjustment methods may yield suboptimal results, especially in situations with small provider volumes or rare events. Propensity score (PS) methods, widely used in observational studies of binary treatments, have shown promising performance with limited observations and events and can be extended to multiple provider settings. This study aims to evaluate the performance of various risk adjustment methods in profiling multiple health care providers that conduct highly standardized procedures, such as coronary artery bypass grafting. A simulation study compared provider effects estimated through PS adjustment, PS weighting, PS matching, and multivariable logistic regression in terms of bias, coverage, and mean squared error (MSE), while varying event rates, sample sizes, provider volumes, and number of providers. An empirical example from cardiac surgery was used to illustrate the different methods. Overall, PS adjustment, PS weighting, and logistic regression produced provider effects with low bias and good coverage. In contrast, PS matching and PS weighting with trimming yielded biased effects and high MSE in several scenarios. Additionally, PS matching became impractical when the number of providers exceeded three. No PS method significantly outperformed logistic regression, except in scenarios with relatively small sample sizes. Propensity score matching performed inferiorly compared to the other PS methods analyzed
Experimental Investigation Pervious Concrete by using GGBS, Microslica and Artificial Fibers
Authors: S Gowthami , R Suganya
Published: August 2023

Abstract: Pervious concrete is a light-weight concrete which is prepared by eliminating the fine aggregate from conventional concrete, also known as 'no fine concrete' or 'porous concrete'. It is a combination of graded coarse aggregates, cement materials and water. Now-a-days we are very much interested in sustainable and eco-friendly way of constructions. It is an important application for sustainable construction. It is traditionally used in parking areas, areas with light traffic, residential streets, pedestrian walkways, and greenhouses. The experimental investigation will be carried out to study the properties of concrete with artificial fibers (Polypropylene fiber & Steel fiber) to increase the strength of the concrete with replacement of cement by different percentage of GGBS & micro silica problems will be discussed in this project.
Implicações no cuidado de um familiar doente: mulheres negras cuidadoras
Authors: Trindade Coelho Camila , Griebeler Oliveira Stefanie , Eisenhardt de Mello Fernanda
Published: August 2023

Introdução: As desvantagens ligadas ao gênero feminino são visualizadas em diversos aspectos da vida, mediante ao patriarcado. É possível compreender que, no caso de mulheres negras, estas se encontram desfavorecidas frente as estruturas sociais, atravessadas por condicionantes de classe, raça e gênero. Além disso, é visto que, em diversos casos, as cuidadoras mulheres, sobretudo, mulheres negras, não escolhem de forma voluntária este papel dentro da conjuntura familiar. Objetivo: Identificar as implicações do cuidado ao familiar adoecido realizado por mulheres negras cuidadoras considerando suas condições socioculturais. Metodologia: Este trabalho é uma revisão integrativa, cuja busca no banco de dados foi realizada em dezembro de 2020, onde 3 resultados foram encontrados na base de dados Web of Science, 48 na base de dados PubMed e 29 na base de dados LILACS. Depois de ler os resumos dos 80 artigos e aplicar os critérios de exclusão, 7 artigos foram selecionados para leitura completa. Finalmente, 4 artigos foram incluídos para análise. Resultados: Apenas um estudo abordou exclusivamente mulheres, e a maioria eram afro-americanos. Dados indicam que, dentro de uma comunidade quilombola, o cuidado com a saúde é repassado do mais velho para o mais novo, como símbolo de respeito aos saberes ancestrais. Além disso, ficou evidente que cuidadores afro-americanos de pessoas com demência precisam de informações de qualidade sobre cuidados e autocuidado, necessitando de recursos em sua comunidade. Conclusão: É possível notar as desigualdades de acordo com as construções históricas, políticas e culturais causadas, para diferenciar homens e mulheres no cuidado familiar. Havendo uma necessidade de debates que tenham como enfoque a população negra, principalmente as cuidadoras, visando estratégias para reduzir sua sobrecarga para cuidar de familiares em adoecimento.
Espacio Cotidiano
Authors: Fuentes-Hernández Pablo , Cerda-Brintrup Gonzalo
Published: August 2023

Three articles in this issue of Arquitecturas del Sur are dedicated to collective housing, as the housing shortage has led to new and better forms of citizen participation in its solution. The Indigenous Temporary Accommodation in Florianopolis handles an essentially Latin American problem: access for Indigenous people to protected state housing. In this case, the presence of the city’s original inhabitants examines the possibilities of physical and symbolic spaces in the contemporary city and the professional role that looks into the responses. Next, the text on collaborative housing analyzes the case of Spain, and its relationship with public management mechanisms. The case of Gran Canaria looks at mutual aid issues, transfer of use, cooperativism, and citizen participation. In this way, the self-construction system of the Andalusian Junta, a practice that is as effective as it is controversial, and representative of a socialist cooperativism and cohabitation developed by the Barcelona City Council, converge in the debate on cooperative management. The third text looks into one of the latest events disclosed on CORVI’s actions, before its dissolution in 1976. It explores a management model that revealed the role of construction companies as a new player in the habitational process for the case of the Santiago Amengual Neighborhood. A second thematic group in this issue, materialized in its last 3 articles, returns to the structural issues of modern-day architecture, whose presence is diving deeper into the disciplinary debate. The places of memory seem to exceed the margins of an understanding based on heritage discourse. The memory and belonging of daily spaces, turn one to the nodes of memory and collective coherence. This is the case of the Community School – Center of Memory and Integrated Action to Care for the Forest of Galilea and the Territory of Colombia. Likewise, the individual, isolated, and selective expressions examine those unusual experiences where otherness exercises protagonism over experiences in the architecture and city of Santiago de Chile. Finally, revisiting the works of a master like Niemeyer opens the possibility for rereading, through actions based on the Portuguese decisions in two of his works: the urban complex of Pena Furada, in Portugal (1965), and Plaza XV, in Rio de Janeiro (1991).
Vivienda colaborativa: Ayuda mutua, cooperativismo y participación en las políticas de promoción pública de vivienda
Authors: Díaz-García Vicente
Published: August 2023

On one hand, this research is framed within the results of two Spanish public housing interventions, and on the other, the beginnings of an extended collaborative housing model on the island of Gran Canaria. The research analyzes collaborative housing and its relationship with the management mechanisms that can or should accompany public policies for housing, by observing the cases of Andalusia and Barcelona, both inspired by Uruguay’s cooperative housing model. After studying the case on the island of Gran Canaria, the need for housing policies that incorporate mutual aid, transfer of use, cooperativism, or citizen participation is proposed.
Music Education Through Autobiographical Digital Storytelling (METADS) at the 14th SAR International Conference on Artistic Research
Authors: Jeffrey Cobbold
Published: August 2023

METADS stands for “Music Education Through Autobiographical Digital Storytelling”. It’s a special initiative for furthering interdisciplinary arts thinking and production that is inspired by music. METADS’ history started in 2017 with Jeffrey Cobbold’s musically rich digital audio sermon album focused on his autobiographical story as a music educator. Included in the sermon are observational digital stories of various music students, which offer approaches to confronting fear through various modes of truth-telling.

In 2020 METADS was mastered by audio engineer Johnny O, who also sang on the song "JOURNAL PROMPT" on the METADS album. The album’s cover art was created by graphic designer Lauren Meyer. In 2021 METADS expanded into a visual art project through Cobbold’s invitation to Meyer to create visualizations for the digital audio sermon album into a comprehensive visual guide/coloring book. Meyer’s involvement in METADS has furthered its progression toward interdisciplinary arts thinking and production inspired by music and storytelling.

For the 14th SAR International Conference on Artistic Research, METADS makes an urgent appeal for music educators and musicians to tend to the stewardship of their relationships in music through the creation of their own autobiographical digital stories, offering them as artistic research in this sensitive area of our musical lives. This is an effort to improve professional practice through investigation of relational fears and the expression of rare relational truths that are often concealed or neglected. METADS also seeks to appeal to the non-musician at the conference who engages in personal storytelling inspired by music or other mediums with a concern for the moral fabric of their creative relationships.
Demanding Equal Inheritance Rights For Women: Tension Among Shari’a and Tunisia’s New Constitution 2014
Authors: Juliandi Budi
Published: August 2023

President  Essebsi  (2017) approved  the  law of gender  equality  in  inheritance  in Tunisia. Instead of gaining public appreciation of Islam, this achievement was seen as contrary to sharia. This research seeks to address whether or not there could be a common ground between  applying  sharia and gender equality through an examination of sharia regarding  inheritance, and, finally, an attempt to show the relationship between sharia and the  Tunisia’s constitution of 2014 in responding to social change. The paper argues that in spite of the constitution’s progressive language, women still face legal discrimination in  their ability  to inherit because of sharia.
Tripartite-structure Transformer for Hyperspectral Image Classification
Authors: Bai Zongwen , Wan Liuwei , Zhou Meili , Jiang Shengqin , Zhang Haokui
Published: August 2023

Hyperspectral images contain rich spatial and spectral information,
which provides a strong basis for distinguishing different land-cover
objects. Therefore, hyperspectral image classification has been a hot
research topic. With the advent of deep learning, convolutional neural
networks (CNNs) have become a popular method for hyperspectral image
classification. However, CNN has strong local feature extraction ability
but cannot deal with long-distance dependence well. Vision Transformer
(ViT) is a recent development that can address this limitation, but it
is not effective in extracting local features and has low computational
efficiency. To overcome these drawbacks, we propose a hybrid
classification network that combines the strengths of both CNN and ViT,
names Spatial-Spectral Former(SSF). The shallow layer employs 3D
convolution to extract local features and reduce data dimensions. The
deep layer employs a spectral-spatial transformer module for global
feature extraction and information enhancement in spectral and spatial
dimensions. Our proposed model achieves promising results on widely used
public HSI datasets compared to other deep learning methods, including
CNN, ViT, and hybrid models.
Developing practical recommendations for drug-disease interactions in patients with hypertension
Authors: Özokcu Kübra , Diesveld Maaike , Gipmans Suzan , Peeters Laura , Born Bert-Jan van den , Borgsteede Sander
Published: August 2023

Abstract Aims This study aims to assess the safety of medication that
can affect blood pressure in patients with hypertension and provide
practical recommendations for healthcare professionals. Methods For the
development of recommendations for the drug-disease interaction (DDSI)
hypertension, a six-step plan that combined literature selection and
multidisciplinary expert opinion was used. The process involved (1)
defining the scope of the DDSI and selecting relevant drugs, (2)
collecting evidence, (3) data-extraction, (4) reaching of expert
consensus, (5) publication and implementation of the recommendations in
healthcare systems and (6) updating of the information. Results An
increase of 10 mmHg in systolic blood pressure and 5 mmHg in diastolic
blood pressure was defined as clinically relevant. Corticosteroids,
danazol, and yohimbine caused a clinically relevant DDSI with
hypertension. Several other drugs with warnings for hypertension in the
official product information, were assessed to have no clinically
relevant DDSI due to minor influence or lack of data on blood pressure.
Drugs with evidence for a relevant change in blood pressure which are
prescribed under close monitoring of blood pressure according to
clinical guidelines, were deemed to be not clinically relevant for
signalling. Conclusions This study provides specific recommendations
that can be implemented directly in clinical practice, potentially
resulting in safer drug use in patients with hypertension and better
healthcare by reducing alert fatigue. Future research should focus on
evaluating the effectiveness of implementation strategies and their
impact on reducing unsafe use of medication in patients with
hypertension.
Shrinking economic MPC of constrained nonlinear systems: An event-triggered constraint relaxation approach
Authors: Tian Yu , He De-feng , Jianbin Mu
Published: August 2023

This paper proposes a novel event-triggered economic model predictive
control (EMPC) scheme with shrinking prediction horizon of constrained
nonlinear systems. Concretely, the triggered mechanism is designed by
relaxing the stability constraint, while the involved parameter can be
used to achieve a sensible compromise between system performance and
computational complexity. The rule of shrinking prediction horizon
shortens the length of the horizon as much as possible, while the length
of triggered interval is ensured to avoid Zero behavior. The utilization
of control sequence is improved. As the prediction horizon becomes
shorter, the state always keeps in the terminal set. The sufficient
conditions guaranteeing the recursive feasibility and stability of the
EMPC are derived. Finally, the effectiveness of the algorithm is
illustrated by a continuously stirred tank reactor example.
Physiology of GPCRs in the nervous system and the contribution of orphan GPCRs
Authors: Iyison Necla Birgül , Abboud Clauda , Abboud Dayana , Abdulrahman Abdulrasheed , Bondar Ana-Nicoleta , Dam Julie , Soner Dogan , Georgoussi Zafiroula , Giraldo Jesus , Horvat Anemarie , Karoussiotis Christos , Karsak Meliha , Castro Alba , Scarpa Miriam , Schihada Hannes , Scholz Nicole , Tuna Bilge Guvenc , Vacek Jan , Vardjan Nina
Published: August 2023

G protein-coupled receptors (GPCRs) are a large family of cell surface
receptors that play a critical role in nervous system function by
transmitting signals between cells and their environment. They are
involved in many, if not all, nervous system processes, and their
dysfunction has been linked to various neurological disorders
representing important drug targets. In this review, we will first
discuss the role of the nervous system GPCRs in the modulation of
tripartite synapse function and how GPCRs control energy metabolism in
the brain. We will then discuss the (patho)physiology and pharmacology
of opioid, cannabinoid, acetylcholine, chemokine, and melatonin GPCRs in
the nervous system. Furthermore, we will briefly report on adhesion GPCR
function in nervous tissues. Finally, we will address orphan GPCRs,
their implication in the nervous system function and disease, and the
challenges that need to be addressed in the future to deorphanize them.
Fatigue limit estimation of metals based on the thermographic methods: A comprehensive review
Authors: Galietti Umberto , Zaeimi Mohammad , Finis Rosa De , Palumbo Davide
Published: August 2023

Infrared Thermography has been under review in the last thirty years due
to its versatility and potential in the detection of the thermal
signature associated with intrinsic energy phenomena due to dissipative
processes, specifically those relying on mechanical fatigue. Nowadays,
it is a well-established technique that can support mechanical and
structural engineers to implement a damage-tolerant design, assess the
residual life, and finally characterize the fatigue behavior of
materials. The aim of this work is to review all thermography-based
approaches and procedures for fatigue limit estimation by rapid tests,
draw considerations on the role of thermal methods in mechanical design
and machine construction, and discuss the pros and cons of each method
and open points. This review is intended on one hand, as a
warning/guideline to direct new research toward issues that have not
been fully resolved or understood yet and on the other hand, to sum up,
what has already been done in the field.
Topic: “Advancing Disease Mitigation: The Imperative for Japanese Encephalitis Vaccination in Bangladesh”
Authors: Khanal Barsha , Shrestha Abhigan Babu , Siddiq Abdelmonem , Oishee Arefin Naher , Nuruzzaman Md. , Jaiswal Vikash
Published: August 2023

Japanese Encephalitis (JE) is a viral disease caused by the Japanese
Encephalitis Virus (JEV) which is a mosquito-borne, single-stranded, RNA
flavivirus belonging to the Flaviviridae family. It is imperative to
note that JE can cause severe inflammation of the brain, leading to
long-term neurological complications or even death in some cases. JE
vaccine provides a crucial defense against this potentially fatal
disease. Given the high prevalence of JE in Bangladesh, widespread
vaccination campaigns and public health initiatives are necessary to
promote awareness and ensure that individuals at risk receive the
vaccine. The commentary emphasizes on how crucial it is that individuals
who are at risk of JE infection receive the vaccine through nation wide
immunization campaign in Bangladesh.