bluuebunny/crossref_metadata_2025 huggingface dataset:
INFECÇÃO POR PNEUMOCOCO EM CRIANÇAS PORTADORAS DE ANEMIA FALCIFORME
Authors: Dos Santos Ana Carolina Valladares , Eugênio Fabiana Maria Costa
Published: December 2022

Introdução: A anemia falciforme é uma doença hereditária decorrente de uma mutação genética que altera a estrutura circular das hemácias, para um formato característico de foice. Isso ocasiona uma perda da mobilidade na corrente sanguínea fazendo com que sofram hemólise, levando ao aparecimento da anemia. Crianças com anemia falciforme se tornam mais susceptíveis a infecções, frequentemente causadas por bactérias encapsuladas. Este trabalho tem como objetivo analisar a associação de informações de como crianças portadoras de anemia falciforme podem ser vulneráveis a infecções por pneumococo. Métodos: Diante disso, foi realizada uma revisão bibliográfica, onde foram utilizados sites de busca, como Google Scholar, SCIELO, totalizando o uso de 18 artigos. Resultados: Por conseguinte, estudos mostram que no Brasil, nascem em média 3.000 crianças por ano com a doença falciforme, tornando esta, a doença hereditária mais frequente no país. E o Streptococcus pneumoniae é o principal causador de infecção nestes pacientes, que devido a sua função esplênica comprometida logo em seus primeiros meses de vida, acaba aumentando o risco de contaminação quando comparado com crianças saudáveis. Podendo levar a morte. Conclusão: Conclui-se que crianças com anemia falciforme são mais susceptíveis a infecções causadas pelo pneumococo e para minimizar os quadros de infecções e complicações, é necessário oferecer informação à comunidade a respeito da importância das medidas profiláticas.

 

Palavras-chave: Infecção; Pneumococo; Anemia falciforme.
The orbital evolution of near-Earth asteroid 159402 (1999 AP10)
Authors: В.В. Емельяненко, , А.П. Карташова,
Published: December 2022

Исследована эволюция орбиты околоземного астероида 159402 (1999 AP10) в прошлом. Проводилось интегрирование уравнений движения для 100 виртуальных объектов с начальными орбитами, взятыми из доверительной области, на промежутке времени 10 млн. лет. С вероятностью 0.8 астероид на этом промежутке времени подходил к Солнцу на расстояние менее 0.1 а. е. С вероятностью 0.2 этот объект пришел на современную орбиту с кометной орбиты.

The evolution of the orbit of near-Earth asteroid 159402 (1999 AP10) in the past was studied. The equations of motion were integrated for 100 virtual objects with initial orbits taken from the con dence region over a time interval of 10 million years. With a probability of 0.8, the asteroid approached the Sun at a distance of less than 0.1 AU during this time interval. With a probability of 0.2, this object entered the current orbit from a cometary orbit.
The first results of DORIS RINEX data processing at the INASAN Analysis Center
Authors: С.П. Кузин,
Published: December 2022

В работе приводятся первые результаты обработки DORIS измерений формата RINEX (Receiver Independent Exchange Format) в центре анализа ИНАСАН - нового вида измерений системы DORIS. Приведено сравнение остаточных погрешностей радиальной скорости по результатам обработки измерений для данных формата RINEX и предшествующего формата doris2.2. Среднеквадратические ошибки для спутника Jason-2 на интервале 2008.5-2019.7 для данных формата RINEX и формата doris2.2 равны 0.427 мм/c и 0.404 мм/c, соответственно. Для спутника Cryosat2 на интервале 2021.5-2021.8 среднеквадратические ошибки форматов RINEX и doris2.2 равны 0.508 мм/с и 0.501 мм/с, соответственно. Полученные среднеквадратические ошибки сопоставлены с результатами среднеквадратических ошибок, полученными другими центрами анализа DORIS данных. Результаты сравнения подтверждают правильность применяемой методики обработки DORIS RINEX данных и используемых моделей.

The paper presents the rst results of DORIS RINEX (Receiver Independent Exchange Format) data processing at the INASAN Analysis Center - a new type of DORIS system measurements. The comparison of the residuals of the radial velocity of measurement processing for RINEX data and the previous doris2.2 format is given. The RMS for Jason-2 satellite in the interval 2008.5-2019.7 for RINEX format data and doris2.2 format are 0.427 mm/s and 0.404 mm/s, respectively. For the Cryosat2 satellite in the interval 2021.5-2021.8 the RMS of the RINEX and doris2.2 formats are 0.508 mm/s and 0.501 mm/s, respectively. The obtained standard errors are compared with the results of standard errors obtained by other DORIS data analysis centers. The results of the comparison con rm the correctness of the DORIS RINEX data processing methodology and the models used.
The ESG Brouhaha: Tempest in a Teacup
Authors: Bhattacharya CB
Published: December 2022

There have been many recent articles and tweets about corporate investors taking Environmental, Social, and Governance (ESG) metrics into consideration for their investment decisions, and how several politicians, business owners, and public figures are reacting to this phenomenon. In large part, the confusion facing ESG is the lack of understanding and agreement about what it is and how we should use it. In reality, ESG is nothing more than a set of metrics, i.e., quantifiable measures, that businesses and other stakeholders can track to better assess how Environmental (e.g., climate change), Social (e.g., human rights abuses) and Governance (e.g., in-house sustainability committees) factors impact a business, and in turn, how the operations of that business impact the environment and society. This article purports to clear the several points of confusion, including what ESG is, the lack of standardization in terms of what to measure and how, what to do with the plethora of ESG ratings available and how purpose-driven companies can use ESG to their full advantage.
Özel Eğitim Alanında Tasarım Tabanlı Araştırma Yöntemiyle Yapılmış Olan Çalışmalar: Sistematik Derleme
Authors: KURT Ali , MELEKOĞLU Meral
Published: December 2022

Bu araştırmanın amacı, özel eğitim alanında tasarım tabanlı araştırma yöntemiyle yapılmış olan çalışmaların incelenmesidir. Araştırmanın yöntemi sistematik derlemedir. Araştırma kapsamında bir üniversitenin veri tabanı, Türkiye Bilimsel ve Teknolojik Araştırma Kurumu Ulusal Akademik Ağ ve Bilgi Merkezi (TÜBİTAK-ULAKBİM) veri tabanı ve Google Scholor yayın dizininde bulunan 22 çalışma incelenmiştir. İncelenen bu çalışmalar belirli değişkenler açısından betimsel analiz yoluyla analiz edilmiştir. Araştırma sonucunda; ele alınan çalışmaların büyük bir bölümünün eğitsel bir amaç için yapıldığı, çok daha az bir kısmının bireylerin yetersizliğinden kaynaklı bir kısıtlılığa yönelik yapıldığı görülmüştür. Ayrıca çalışmalarda çoğunlukla bir öğretim tasarımının geliştirilmesi, uygulanması ve değerlendirilmesi amaçlanmıştır. Çalışmalarda etkililiğin değerlendirilmesinde genellikle durum çalışmasının tercih edildiği belirlenmiştir. Bunun yanında çalışmaların yapıldığı konulara göre en fazla maddenin halleri ve ısı, okuma-yazma öğretimi ve yaşamımızdaki elektrik konusunun çalışıldığı ortaya çıkmıştır. Tüm bunlarla birlikte veri toplamada en fazla gözlem ve görüşme formlarının kullanıldığı, verilerin analizinde ise çoğunlukla betimsel analizin tercih edildiği tespit edilmiştir. Son olarak, ele alınan çalışmada daha çok olumlu sonuçlara ulaşılmıştır.
Restoring healthy gut microbiome in poultry using alternative feed additives with particular attention to phytogenic substances: Challenges and prospects
Authors: Shehata Awad A. , Attia Youssef , Khafaga Asmaa F. , Farooq Muhammad Z. , El-Seedi Hesham R. , Eisenreich Wolfgang , Tellez-Isaias Guillermo
Published: December 2022

The majority of pathologies in poultry are linked to intestinal chronic inflammation due to a disbalance of the gut microbiota. Thus, a healthy microbiota drives the gut integrity, and the gut’s biological and metabolic functionalities, including efficacious use of nutrition, but also immunity, and neuroendocrine systems. However, many external factors are disturbing a stable, healthy gut microbiota. Heat stress, dysbiosis, leaky gut syndrome, and mycotoxins are the main “secret killers” in poultry that lead to chronic oxidative stress and inflammation, which in turn impact the health and animal performance. Additionally, chronic stress in poultry is linked with the emergence of antimicrobial resistance (AMR), which the WHO has recently identified to be among the most important problems threatening human health globally that increased the demand for safe antimicrobials to treat the collateral damages resulting from dysbiosis. Several alternative feed additives such as probiotics, prebiotics, fatty acids, and amino acids have been described to restore intestinal microbiota. Additionally, some phytogenic substances have anti-inflammatory and antioxidant activities. These natural products are also capable to modulate gut microbiota in a symbiotic equilibrium, thereby enabling the intestinal tract to withstand both infectious and non-infectious stressors. Nevertheless, several challenges, such as the bioavailability, rate of absorption, quality inconsistency, public acceptance, and cost-effective delivery methods, make the feasibility and application of phytogenic substances on a commercial scale complicated. In this review, the main drivers of chronic inflammation in poultry have been discussed. Additionally, the potential use of alternatives to antibiotics to restore the gastrointestinal microbiota in poultry and the possibilities for overcoming breakdowns in poultry farming were highlighted
PUBLIC DEBT AND ITS EFFECT ON THE NIGERIAN ECONOMY
Authors: Benedicta OWONYE  , Godwin OBONOFIEMRO
Published: December 2022

The study examined the impact of public debt and its effect on the Nigerian economy for the period of 1985-2020 (36years). This was done respect of measures of public debt, namely; Domestic Debt Stock (DDS), External Debt Stock (EXTDS), External Debt Servicing (EXTDSG) and Total Public Debt (TPD) and how they affect Nigerian economy {proxy with Real Gross Domestic Product (RGDP)}. The method of data collection used in this study is the secondary source of data (time series data), from the CBN Annual Report and Debt Management Office Annual Reports. The data set was described using descriptive statistics and the unit root test was conducted to ascertain if the data are stationary in order to have accurate regression result. The correlation analysis will be use to ascertain the co-movement of the independent variables in relation to the dependent variable while the Multiple Regression analysis were employed with the aid of E-VIEW version 9.0 for the purpose of testing the research hypotheses raised. The finding revealed that EXTDSG have positive and significant effect on RGDP while DDS, EXTDS and TPD has negative and insignificant effect on RGDP proxied for Nigerian economy. Hence, the study concluded that public debt does not exerts significant effect on the Nigerian economy. This study recommends that since foreign debt impacted negatively on Nigerian economy, government should discontinue borrowing to finance the national budget, in a bid to achieve key macro-economic goals such as price stability, improvement in standard of living, provision of social and economic amenities amongst others, which will bring about economic growth and development in Nigeria.

Keywords: Domestic Debt Stock, External Debt Stock, Debt Servicing and Real Gross Domestic Product.
TOPTAN VE PERAKENDE SEKTÖRÜNDE FAALİYET GÖSTEREN FİRMALARIN FİNANSAL PERFORMANSLARININ KARŞILAŞTIRMALI ANALİZİ
Authors: AKTULUM Ülviye , UMUT İklim Elif
Published: December 2022

Bu çalışmanın temel amacı, toptan ve perakende sektöründe faaliyet gösteren firmaların finansal performanslarının karşılaştırılmasıdır. Çalışmanın örneklemi, hisse senetleri 2018:Q4-2021:Q3 döneminde BIST’de (Borsa İstanbul) işlem gören 7 toptan, 13 tanede perakende şirket oluşturmaktadır. Likidite, kârlılık ve finansal yapı rasyoları kullanarak çeyrek dönemler bazında Mann-Whitney U testi, tüm döneme ait karşılaştırmada Bağımsız-İki Örnek T-Testi, her iki sektör üzerinde etkili olan rasyoları tespit etmek için ise Lojistik Regresyon analizi kullanılmıştır. Elde edilen bulgularda, ortalama testlerde toptan sektöründe faaliyet gösteren firmaların finansal performansının genel olarak perakende sektöründe göre daha başarılı olduğu görülmüştür. Lojistik Regresyon analizinde ise, cari oran, likit oran ve uzun vadeli borç oranı katsayıları anlamlı bulunmuştur.
Abemaciclib (Verzenio)
Authors: CADTH
Published: December 2022

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.

The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.

This review assesses abemaciclib (Verzenio), 50 mg, 100 mg, 150 mg, 200 mg oral tablet.

Indication: In combination with endocrine therapy for the adjuvant treatment of adult patients with HR-positive, HER2-negative, node-positive early breast cancer at high risk of disease recurrence based on clinicopathologic features and a Ki-67 test score ≥ 20%.
Exploring the Growth of Indian’s Foreign Direct Investment Equity Inflow amid Covid-19 Outbreak
Authors: Rena Ravinder , Mbukanma Ifeanyi
Published: December 2022

Purpose: The aim of this paper is to explore the growth of Indian’s Foreign Direct Investment (FDI) equity inflow amid Covid-19 outbreak. Design/methodology/approach: in-depth review of current and previous literatures from journals and periodic publications of legitimate organizations both local and international on the evolution and the trend of Covid-19 pandemic as well as it impacts on Indian’s FDI was conducted. Findings : The findings however revealed a major drop in net FDI flows globally, but on the contrary, a significant increase was recorded in India. Secondly, key sectors such as services sectors, computer software and hardware, telecommunications, trading, automobile, construction development, chemicals, and pharmaceuticals was revealed to have attracted the maximum FDI inflow to India amid the Covid-19 pandemic. Practical implications: The study recommended that a cohesive policy that further strengthens FDI by identifying and creating incentives for other main industrial sectors could further promote the continued attractiveness of FDI to India. Originality/value: The current study is an original contribution in the field of FDI inflow in India amid the COVID pandemic.
"Pathway to Corporate Sustainability: Drivers & Dimensions – A Review Study "
Authors: Ramchandani Sahil , Singh Ajay Kumar
Published: December 2022

Purpose: The objective of this paper is to identify the factors that drive CS and provide a clear understanding of its dimensions, thereby laying a roadmap for modern-day organizations, striving to achieve sustainability. Design/methodology/approach: In this paper, an exploratory study has been undertaken through an extensive literature review of research papers and articles from varied journals, books, reports and online sources. Findings: Based on the literature reviewed, the paper identifies environmental responsibility, social responsibility, corporate reputation, compliance issues and organizational factors as the five major drivers of CS. It also gives an overview of Triple Bottom Line (TBL) based definitions of CS, proposed by different scholars and provides favourable arguments towards the adoption of a holistic TBL approach, maintaining a balance between the environmental dimension (planet), social dimension (people) and economic dimension (profit). Research limitations/implications: The research provides a conceptual framework related to the drivers and dimensions of CS. However, further research is required to find the right mix of drivers that fuel CS in companies and to understand the actual balance of the TBL dimensions that exists in the modern-day organizations. Originality/Value: The paper provides findings which are useful for academicians as well as practitioners. It provides a conceptual foundation for future researches with vast potential, worthy of empirical validation, along with sound theoretical knowledge about the drivers and dimensions of CS, necessary for smooth implementation of CS practices and initiatives in their organizations.
The High 5 Habit: Take Control of Your Life with One Simple Habit by Mel Robbins
Authors: Soni Ushmeet Kaur
Published: December 2022

The book "The High 5 Habit" makes a startling claim: a single change to your daily routine could help you break free from your old, self-limiting thinking and into high gear. Self-improvement appears to be easier than ever before with this plan for life change, which is intertwined with personal experiences and scientific data. Mel Robbins, the book's author, is a best-selling author and personal-development guru who lives in New England with her husband and three children. She is the creator of the number-one podcast on Audible, "Start Here: Pep Talks for Life." One of her other books is "The 5 Second Rule".
Bezeichnungen von Friedhofsalleen als Gegenstand der onomastisch fundierten Untersuchungen
Authors: Owsiński Piotr A.
Published: December 2022

Der als Pilotprobe und Initiierung der breit angelegten Untersuchungen konzipierte Beitrag ist ein onomastisch geprägtes Studium zur Motivierung der Friedhofsalleennamen, die innerhalb der Friedhofsmauern in Busko-Zdrój, in der Heiligkreuz Woiwodschaft (Polen), im Gebrauch sind. Den Ausgangspunkt der vorliegenden Erörterungen bildet die Annahme, dass die Struktur eines Friedhofs als Nekropole dem öffentlichen Raum einer Stadt ähnelt, in dem die Straßen- und Platznamen seit Jahrhunderten ihre Anwendung finden. In Anlehnung an die Ergebnisse der letztens florierenden, sowohl historischen als auch synchronischen Analysen der Systeme von Hodonymen und Agoronymen in den konkreten Städten wurde der Versuch unternommen, die Friedhofsalleenbezeichnungen (Nekrohodonyme) im Kontext der städtischen Realität sowie aus der Perspektive des sprachlichen, in der Sprache eines konkreten Sprach- und Kulturkreises ausgedrückten Weltbildes zu interpretieren. Anhand der Explorationsschlüsse lassen sich die Konzeptualisierung der Wirklichkeit sowie die Produkte dieser Weltkonzeptualisierung erkennen. Die Untersuchung beweist eindeutig, dass die Friedhofsalleennamen dieselben Funktionen erfüllen, die den städtischen Hodonymen und Agoronymen zugeschrieben werden.
Colour naming and use preferences in Spanish text typologies (1492−1700)
Authors: Cáceres-Lorenzo María-Teresa
Published: December 2022

This article is intended to provide a quantitative analysis of colour names and their appearance in certain text typologies between 1492 and 1700. The terms for colour increased in Spain’s Golden Age because of the need to describe Spanish and American reality in detail. A review of the specialised literature has provided us with a lexicon of 499 terms of which 277 colour words are recorded in Golden Age documents according to various diachronic corpora. The method for collecting and analysing texts has provided a lexicon of 66 terms for colour with different degrees of preference for a specific type of document. In addition, 23 of these words have been found to indicate greater numerical specialisation by typology. These lexical units are mediaeval terms used especially in scientific prose and lyric, followed by historiography and society prose. These quantitative data represent the initial stage of research to which other issues must be added in the future such as the context in which these terms appear and the semantic changes that occur in each of the texts.
Typen und Funktionen des Code-Switchings in einer multilingualen deutsch-litauischen Geschäftsverhandlung
Authors: Gelunaite-Malinauskiene Gintare
Published: December 2022

In dem Artikel wird eine multilinguale interkulturelle Geschäftsverhandlung zwischen den deutschen und litauischen Geschäftspartnern analysiert, wobei ins Zentrum des Interesses die Fragen nach den Funktionen und Gründen des Codes-Switchings rücken. Bei der Auswertung des Audiomaterials und der Bestimmung des Gesprächstyps „Geschäftsverhandlung“ wurde von der Auffassung ausgegangen, dass es sich dabei um eine Kommunikationssituation handelt, in der die Beteiligten von verschiedenen Zielvorstellungen ausgehend eine Vereinbarung treffen wollen. Im ersten Analyseschritt wird die Grobstruktur des ausgewählten Gesprächs ermittelt, um feststellen zu können, ob ein Ziel / Teilziel des Gesprächs erreicht wird. Dabei handelt es sich auch um die Ermittlung der Mehrsprachigkeitsstruktur des Gesprächs, so etwa die Zahl der Sprachenwechsel. An der Abfolge des Code-Switchings wird dann mikroanalytisch untersucht, wer gesprächslokal auf welche Weise und wozu die Sprache wechselt, welchem besonderen Zweck der jeweilige lokale Sprachenwechsel vor dem Hintergrund des allgemeinen Gesprächsziels dient und welche institutionellen beziehungsweise interkulturellen Kontextualisierungshinweise dabei realisiert werden. Die exemplarische Analyse bezieht sich auf die theoretisch-methodologischen Ansätze von Blom, Gumperz, Auer, Günthner, Heritage, etc., wobei eine besondere Bedeutung den Studien zukommt, die sich mit dem Code-Switching in der institutionellen Interaktion, speziell aus der Sicht der Gesprächsanalyse beschäftigen (David, Apfelbaum, Meyer, etc.).
Análise dos indicadores de qualidade dos exames de citologia cervical do município de Caruaru/PE: Uma estratégia para incentivar o monitoramento da qualidade
Authors: Dos Santos Mariano Antonio , Etlinger-Colonelli Daniela
Published: December 2022

No Brasil, a detecção precoce do câncer de colo uterino é recomendada através da realização periódica do exame citopatológico. A Portaria 3.388/2013 (QualiCito) determina padrões e propõe a análise de indicadores para monitoramento da qualidade dos exames. O objetivo deste estudo foi avaliar os indicadores de qualidade dos exames citopatológicos realizados no município de Caruaru-PE, em 2019. Os dados foram obtidos a partir dos registros de exames no Siscan, tabulados em Excel e foram calculados os indicadores de qualidade propostos pelo Ministério da Saúde. Dos 17.316 exames realizados, 226 (1,3%) foram rejeitados na fase pré-analítica e 370 (2,1%) foram insatisfatórios para avaliação.  O erro de identificação de amostras e excesso de piócitos foram as causas principais de rejeição pré-analitica e avaliação insatisfatória. Dos 16.824 exames satisfatórios, o índice de positividade foi de 9,4%, o índice atipia/exames satisfatórios foi 6,5%; atipias /exames alterados 68,9%, razão atipias/lesões 3,2% e o percentual de Hsil foi 0,4%. O índice de positividade apresentou-se no limite superior de referência (3 a 10%). Os indicadores relacionados a categoria ASC apresentaram valores acima da referência. Má fixação do material na coleta ou dificuldade dos profissionais que realizam a leitura das lâminas em interpretar as células podem interferir na análise e refletir em elevação dos índices. Os resultados ressaltam a necessidade de treinamento e reciclagem dos profissionais envolvidos na coleta e diagnóstico. O monitoramento periódico da qualidade nos laboratórios de citopatologia é fundamental para a melhoria da qualidade do serviço prestado à população.
Perbandingan Pengaruh Agen Plasmid Curing Acriflavine dan Acridine Orange (AO) terhadap Laju Plasmid Curing dengan Kuantifikasi Fluoresensi Ekspresi Protein GFP pada Bakteri Escherichia Coli PRSET-emGFP
Authors: Gultom Jonathan Harris , Fathiya Azka , Auria Ajeng Farahita , W Ayodya Kuncoroadi Y , Arandri Nadhira Azzahra , Rahman Ahmad Hafiz Husamuddin
Published: December 2022

Plasmid curing is an activity to remove plasmids in a bacterium. Plasmid itself is a structure that can carry genes that are beneficial for bacteria, such as making the bacteria resistant to antibiotics. Acridine Orange (AO) and Acriflavine are intercalating agents that function to break down the super helical shape of plasmid DNA and then form circular or open linear plasmid DNA which is used to carry out Plasmid Curing in this study and then compare its effect on the rate of plasmid curing by fluorescence quantification of GFP protein expression. on Escherichia coli PRSET-emGFP bacteria. The results obtained from this experiment were the rate of plasmid loss per generation obtained by measuring the activity of the GFP reporter on the recombinant E. coli model given the curing agent Acridine Orange was 9.52% for the AO 50 treatment, 44.2% for the AO 100, 10.4% for the AO 50 treatment. Akriflavina 250, and 0.836% for Acriflavine 125. Therefore, it can be concluded that the Acridine Orange treatment was more effective than the Acriflavine treatment against the pRSET-EmGFP recombinant E. coli curing plasmid.
Pengaruh Pemberian Pangan Fungsional Gracillaria sp dan Kopi Terhadap Penurunan Berat Badan pada Mencit
Authors: Rosidah Nuraedi , Fera Melly , Nurwati
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian formula rumput laut Gracillaria sp dan kopi terhadap penurun berat badan pada mencit serta untuk mengetahui mana formula pangan fungsional antara Gracillaria sp dan kopi yang lebih berpengaruh terhadap penurunan berat badan pada mencit. Penelitian ini dilaksanakan dengan metode kuantitatif True Eksperimental Post Test Only Control Group Design dengan menggunakan Rancangan Acak Lengkap (RAL) Hasil uji menunjukkan perbedaan bermakna antara BB mencit pre-test dan post-test, Hasil uji one way ANOVA menunjukkan formula terbaik yang paling berpengaruh adalah P3 Gracillaria sp 32ml/hari+ Kopi 1,08ml/40gram BB dapat menurunkan BB mencit obesitas 31,41gram menjadi 20,83gram dengan nilai p < 0,05 hampir setara dengan pembanding orlistat (K+) dari berat 32,12gram menjadi 21,46gram. Hasil uji Kruskal-Wallis p > 0,05, menunjukkan perbedaan tidak bermakna dan tidak berpengaruh terhadap konsumsi mencit. Kandungan serat, flavonoid, dan asam klorogenat mengurangi pemecahan glukosa, serta berperan menghambat aktivitas enzim lipase menghidrolisis lemak penyebab kegemukan.
Analisa Loyalitas Pelanggan Fraser Residence Menteng yang Dipengaruhi Kualitas Pelayanan, Promosi, Persepsi Harga dengan Kepuasan Pelanggan Sebagai Variabel Mediasi
Authors: Gaol Evania Lumban , Budiono Aris
Published: December 2022

Tujuan di dalam penelitian ini untuk menganalisa Loyalitas pelanggan yang dipengaruhi oleh kualitas pelayanan, promosi dan persepsi harga dan cara meningkatkannya. Data diperoleh pada bulan April 2022 dengan jumlah 130 responden yang merupakan pelanggan. Teknik yang digunakan adalah teknik Roscoe untuk mengambil penelitian, lalu dikurangi 30 responden untuk uji Validitas maupun uji Reliabilitas menggunakan software SPSS. kemudian 100 responden yang digunakan untuk uji path analisis menggunakan software SmartPls semuanya adalah pengunjung di Fraser Residence Menteng. Dengan menggunakan analisis Teknik jalur untuk melihat jalur langsung dan tidak langsung sebagai variable terikat terhadap variable tidak terikat. Penelitian ini menghasilkan beberapa kesimpulan sebagai berikut: Kualitas pelayanan tidak berpengaruh terhadap kepuasan pelanggan, Promosi berpengaruh terhadap kepuasan pelanggan, Persepsi harga berpengaruh terhadap kepuasan pelanggan, Kualitas pelayanan tidak berpengaruh terhadap loyalitas pelanggan, Promosi tidak berpengaruh terhadap loyalitas pelanggan, Persepsi harga berpengaruh terhadap loyalitas pelanggan, Kepuasan pelanggan berpengaruh terhadap loyalitas pelanggan, Kualitas pelayanan tidak berpengaruh terhadap loyalitas pelanggan melalui kepuasan pelanggan, Promosi tidak berpengaruh terhadap loyalitas pelanggan melalui loyalitas pelanggan, persepsi harga berpengaruh terhadap loyalitas pelanggan melalui kepuasan pelanggan.
Faktor-Faktor Yang Berhubungan dengan Kontrol Gula Darah Pasien DM Tipe 2 di RSUD Dr. Pirngadi Medan Tahun 2017-2018
Authors: Rajagukguk Marlina
Published: December 2022

Diabetes adalah masalah global. Diabetes dapat menyebabkan kematian, disabilitas, menyerang pada saat memasuki usia produktif atau mengurangi harapan hidup di usia lanjut. Diabetes merupakan salah satu dari 10 penyebab kematian secara global. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kontrol gula darah pasien DM Tipe 2 di RSUD. DR. Pirngadi Medan yang dilakukan dengan mengambil data rekam medik pasien yang dikumpulkan hanya satu kali pada waktu tertentu pada tahun 2019. Metode penelitian ini adalah analitik observasional dengan pendekatan cross sectional Total sampel sebanyak 96 orang, data rekam medik penderita dewasa DM Tipe 2, dimana sampel diperoleh dengan teknik consecutive sampling. Perhitungan statistik dengan menggunakan SPSS. Hasil penelitian menunjukkan responden sebanyak 96 orang dengan kategori menderita DM Tipe 2 sebanyak 58 dan kategori tidak menderita DM Tipe 2 sebanyak 38 orang. Seluruh variabel (IMT, Tekanan Darah dan HbA1c) memiliki hubungan dengan DM Tipe 2. Responden yang memiliki tekanan darah hipertensi berisiko menderita DM Tipe 2 sebesar 8 kali dibanding dengan mereka yang memiliki tekanan darah normal. Berdasarkan penelitian ini disimpulkan bahwa ada hubungan IMT, tekanan darah dan HbA1c terhadap DM Tipe 2 dengan variabel dominan tekanan darah. Implikasi penelitian ini diharapkan dapat menjadi bacaan atau referensi bagi pihak yang berkepentingan berkaitan dengan studi mengenai diabetes.
Kinerja Aparatur Desa dalam Pelayanan Publik di Desa Tanah Towa Kabupaten Bulukumba
Authors: Afdal Andi Ahmad Malikul , Syam Andi Armayudi , Herman Herman
Published: December 2022

Pelayanan publik adalah aktivitas organisasi atau lembaga yang memberikan pelayanan terhadap individu atau kelompok masyarakat sesuai dengan tujuan dari lembaga tersebut, Pemerintah merupakan pelayan bagi masyarakat agar kebutuhan masyarakat dapat terpenuhi maka dari itu, Pemerintah harus menyediakan pelayanan yang maksimal agar kepentingan tersebut dapat terpenuhi dengan lancar. Pemerintah Desa sebagai ujung tombak yang bersentuhan langsung dengan masyarakat harus paham betul apa yang menjadi kebutuhan masyarakat agar dapat memberikan pelayanan yang tepat dan maksimal kepada masyarakat, Aparat Desa juga merupakan kunci dari kualitas pelayanan yang ada di Desa namun, keterbatasan yang ada di Desa kerap kali menimbulkan berbagai macam kendala sehingga kualitas pelayanan kerap kali tak sesuai harapan masyarakat. Di Desa Tanah Towa Kabupaten Bulukumba sendiri tidak terlepas dari masalah pelayanan publik yang diberikan Aparat Desa kepada masyarakat, atas dasar tersebut penelitian ini berfokus pada kinerja Aparatur Desa dalam pelayanan publik di Desa Tanah Towa  Kabupaten Bulukumba dan kemudian menganalisa masalah tersebut khususnya respons aparatur desa dalam memberikan pelayanan, melalui indikator kinerja antara lain, produktivitas, Kualitas layanan, responsivitas, responsibilitas dan akuntabilitas. Hasil penelitian ini menunjukkan  bahwa Aparat Desa Tanah Towa telah memberikan kualitas pelayanan yang baik bagi masyarakatnya, namun tidak bisa diungkiri bahwa dalam kualitas pelayanan yang diberikan oleh Aparat Desa masih terdapat kekurangan dalam pengaplikasiannya.
Tinjauan Atas Pemberitaan Yang Berindikasi Adanya Delik Pencemaran Nama Baik di Media Massa
Authors: Sufriaman  , Mahka Muh. Fachrur Razy , Jaya Karman
Published: December 2022

Pemberitaan di media massa (pers) baik cetak maupun elektronik maupun media online merupakan instrumen dalam tatanan hidup bermasyarakat yang sangat vital bagi peningkatan kualitas kehidupan warganya. Selain fungsinya sebagai media informasi dan komunikasi, pers juga merupakan refleksi jati diri masyarakat karena apa yang dituangkan dalam sajian pers hakikatnya adalah denyut kehidupan masyarakat dimana media informasi itu berada. Dari tampilan pers itulah sebagian wajah masyarakat, baik tingkat kemajuan maupun taraf berpikirnya itu kemudian dapat dicermati. penelitian ini ditinjau dari sifatnya adalah penelitian deskriptif, penelitian deskriptif ini terbatas pada usaha mengungkapkan suatu masalah atau keadaan sebagaimana adanya bersifat untuk mengungkap fakta hasil penelitian ini ditekankan untuk memberikan gambaran secara objektif tentang gambaran sebenarnya dari objek yang diteliti. Pendekatan digunakan dalam penelitian ini pendekatan normatif doktrinal. dalam penelitian ini sumber data yang digunakan adalah data sekunder, teknik pengumpulan data yang dipergunakan dalam penelitian ini adalah metode kepustakaan atau penelitian lapangan, yaitu dengan cara mencari dan menghimpun data, mengklasifikasikan data yang relevan dengan pencemaran nama baik melalui media massa baik media cetak maupun media online dan ditinjau dari perspektif yuridis yang terdapat dalam literatur-literatur kepustakaan, dalam upaya penyelesaian atas pemberitaan karya jurnalistik yang dianggap sebagai pencemaran nama baik sebenarnya dapat diselesaikan dengan mengefektifkan hak jawab yang merupakan hak dari objek pemberitaan melalui Dewan Pers.
Resiliensi Remaja Muslim Yatim Piatu Yang Tinggal Di Panti Asuhan Berbasis Pendidikan Islam Di Kabupaten Pemalang
Authors: Firmansyah Fitri Awan Arif
Published: December 2022

Tujuan dari penelitian ini adalah mengetahui sejauh mana resiliensi pada remaja yatim piatu yang tinggal di panti asuhan berbasis pendidikan Islam di Kabupaten Pemalang. Dalam menghadapi masa depan serta permasalahan hidup. Subjek penelitian ini adalah remaja yatim piatu yang tinggal di panti asuhan sebanyak lima orang. Metode penelitian data yang digunakan dalam penelitian ini ialah wawancara dan observasi. Teknik analisis data yang digunakan dalam penelitian ini ialah dengan pengumpulan data, mereduksi data, penyajian data, triangulasi data, dan menyimpulkan data. Hasil analisis data ialah terdapat lima cara dalam anak yatim piatu panti asuhan untuk mengembangkan resiliensi, Dengan menggunakan dukungan sosial, Kekuatan diri, Komunikasi dan role model, Menyelesaikan masalah dan berpikir positif, Membangun Kesadaran Kritis.
Küresel Eğitim Şirketlerinin Güçlü Yönlerinin İncelenmesi
Authors: Saygılı İnan
Published: December 2022

In this study, the related themes will be touched upon by focusing on the structural, functional and situationally strong and effective aspects of global education companies, which are facing us as an important educational force. Global education in the new economy in the globalization process modelling the long life of a company to maintain a competitive advantage of sustainability to provide high, to strengthen existing structural conditions, to obtain information, to control the processes of analysis and synthesis, application and evaluation mechanisms allow them to continue with the methodological tools and the right processes to adapt to the sine qua non of a global education company, and woodland. It is of vital importance for global education companies to maintain their existence and achieve success in the current situation and in the future, to design their future, to develop the necessary operational processes and to create a global education plan and program in order to eliminate the negative aspects of global education companies. Although global education companies have been the subject of many studies, researches and studies at the present stage, the problems experienced by global education companies in the globalization process have remained a field that is rarely examined. In this study, it has been tried to put forth a little effort in terms of eliminating the deficiency in question. Key Words: Education, Global Company, Education Company
Eğitim Yönetiminde Girişimci Önderlik Uygulamalarının İncelenmesi
Authors: Tüzer Soner , Üstün Figen
Published: December 2022

In this study, it is aimed to examine entrepreneurship and entrepreneurial leadership practices in educational management. The phenomenon underlying entrepreneurship will be created. What essentially makes an individual an entrepreneur is that he can create a new perspective, new corporate values, new production processes, new products or new ways of doing business in a new institution, environment. All entrepreneurial activities actually converge around the creation of new ideas. Therefore, knowing how creativity begins and progresses is quite important for a successful entrepreneurship. In fact, creativity is a fundamental factor not only for entrepreneurial behavior, but for any kind of work within an educational institution. As in all organizations aiming for growth and change, it is an important competitive force for educational institutions. It is a way to respond to the change in the environment. Thanks to entrepreneurial leadership, it is possible for the institution to keep up with the changes in its environment by developing new techniques or services in the educational environment, applying new educational processes. Key Words: Education Management, Entrepreneurship, Entrepreneurial Leadership
AVUSTRALYA MUTFAK KÜLTÜRÜNÜN TARİHSEL GELİŞİMİ VE AVUSTRALYA’NIN GASTRONOMİ İMAJINA YÖNELİK ÇALIŞMALAR
Authors: ÜNER Emir Hilmi , DURLU-ÖZKAYA Fügen
Published: December 2022

Bu çalışmada Avustralya mutfak kültürünün tarihsel gelişimi, kıtanın ilk yerleşimcileri olan Aborjinlerin beslenme kültürlerinden başlayarak günümüze kadar gelen süreç içerisinde incelenmiştir. Avustralya kıtasına yaklaşık 50.000-60.000 yıl önce yerleştiği düşünülen Aborjinler yaşam ve beslenme şekillerini 18. yüzyıla kadar korumayı başarmışlardır. Bu dönem içerisinde tarım ve hayvancılık yapmadan ihtiyaçlarını doğrudan doğadan temin edebilmişlerdir. Kıtaya ilk olarak 18. yüzyılda Avrupalıların yerleşmesiyle başlayan hızlı dönüşüm süreci günümüze kadar devam etmiştir. Süregelen yoğun göç hareketleri, yaşanan toplumsal, ekonomik ve politik değişimler gıda üretim süreçlerini ve beslenme kültürünü de tamamen değiştirmiştir. Bu değişim süreci dünya gastronomi tarihinin daha iyi anlaşılabilmesi için pek çok önemli ipucunu da ortaya koymaktadır. Destinasyonların sahip olduğu mutfak kültürü ve gastronomik değerler günümüzde tek başına birer seyahat motivasyonu haline gelmiştir. Bu değerler ayrıca destinasyon seçim sürecinde belirleyici olan önemli unsurlardan biridir. Bu nedenle özellikle son yıllarda Avustralya’ya özgü gastronomik değerlerin yaşatılması ve tüm dünyaya tanıtılması yönünde önemli gastronomi imajı çalışmaları gerçekleştirilmektedir. Bu çalışmalar sonucunda hem ülkeyi ziyaret eden yabancı turistlerin yoplam yiyecek içecek harcamalarının arttığı (%38) hem de Avustralya’nın gastronomi imajının olumlu yönde değiştiği belirlenmiştir. Bu araştırmanın amacı, Avustralya mutfak kültürünün tarihsel gelişimini ve dünyada tanınan, özgün bir Avustralya mutfağı (Mod oz:modern-ausse cuisine) oluşturmaya yönelik gastroomi imajı çalışmalarını literatür taraması yöntemiyle incelemektir.
Empathy in the Math Classroom
Authors: Duggan Katherine
Published: December 2022

Improving Discourse in Mathematics Education
Exploring Students’ Geometrical Thinking Through Dynamic Transformations Using 3D Computer-Based Representations
Authors: Markopoulos Christos , Bruck Patrick , Petta Koralia
Published: December 2022

This paper examines Grade 6 students’ thinking about geometrical solids and their properties in the context of a computer-based task. The main focus is to explore how students interact with a number of tasks based on the dynamic transformation of computer-based representations of 3D solids in a geometry classroom with the aid of a Dynamic Geometric Environment. The analysis of two teaching experiments suggests that the dynamic transformations of geometrical solids encourage the students to investigate relationships between the solids and their properties and their 2D representations. Through the tasks, students realize the existence of non-trivial conventions in 2D representations and become aware that angles and edge dimensions may be distorted. The study provides insight into student learning around geometric solids and their properties, and consequently an opportunity to enhance the teaching of 3D geometry.
Pre-Service Teachers' Discourse Moves During Whole Class Mathematical Discussions: An Analysis and Proposed Framework
Authors: Ducharme Alden , Smith Carmen Petrick , King Barbara
Published: December 2022

Learning to facilitate whole-class mathematical discussions is a complex task. Teachers must become adept at using discourse moves to elicit and extend student thinking and move discussions towards a mathematical point. Practice-based mathematics methods courses give pre-service teachers opportunities to rehearse these moves in a controlled setting. Providing opportunities for practice, often called rehearsals or approximations of practice, have been shown to be effective at developing pre-service teachers' abilities to use discourse moves, but we still do not have a clear understanding of the types of discourse moves pre-service teachers use during discussions or how these moves change over the course of a discussion. In this article, we analyze. whole-class discussions facilitated by pre-service teachers to determine the types of discourse moves used as the discussion progresses. Based on this data and relevant literature, we propose a framework for the structure of whole-class mathematical discussions.
Psychometric Properties of the Pakistani Version of the Fagerstrom Test for Nicotine Dependence
Authors: Khalid Muhammad Talha , Bhatti Mazhar Iqbal
Published: December 2022

The Fagerstrom Test for Nicotine Dependency (FTND) has been widely used to assess nicotine dependence. The current study intended to investigate the psychometric properties and utility among regular cigarette users. The Fagerstrom Test for Nicotine Dependency (FTND) has been widely used to assess nicotine dependence. But there has been no evaluation of FTND psychometric properties in the context of Pakistani culture. Thus, the current study intended to investigate the psychometric properties and utility among regular cigarette users in Pakistan. The study was based on a cross-sectional survey design. Regular smokers were selected as a study sample, with the age range of 25 to 40 years. The sample was collected twice. First, for the translation purpose, a sample of 40 regular smokers was collected, and for final confirmatory validation (i.e., Confirmatory Factor Analysis [CFA]) of the translated version of the scale, a sample of 500 regular smokers was collected from different areas of Gujranwala by using a purposive sampling technique. Pearson correlation, alpha reliability analyses, and CFA were used by utilizing SPSS (version 26) and AMOS (version 10). There were significant positive correlations (r values ranging from .80 to .83) found between FTND in Urdu and FTND in English version. The alpha reliability of the scale was satisfactory (i.e., 0.76). Confirmatory Factor Analysis validated the final six items Urdu version of the scale. The translation and cross-lingual validation of the Pakistani version of the FTND scale confirmed its cross-cultural use in regular smokers in Pakistan. The study has important implications in the indigenous context of Pakistan.
¿Es una buena idea la maximización de los precedentes y de la jurisprudencia? Notas introductorias a la discusión
Authors: Iuspa Santelices Carla , García Yzaguirre Víctor
Published: December 2022

Este artículo tiene por objetivo presentar los principales puntos de la discusión alrededor del texto “Sobre la maximización de los precedentes y de la jurisprudencia” de Álvaro Núñez Vaquero, formulados por Sandra Gómora, Luiz Guilherme Marinoni, y Luca Passanante. Para ello, vamos a empezar por reconstruir las tesis del autor; luego presentaremos brevemente las críticas formuladas a estas por los y la comentarista, así como las respuestas del autor; y finalmente formularemos algunos posibles problemas sobre los cuales seguir discutiendo.
Sostenibilidad social y arquitectura: una revisión sistemática de la literatura
Authors: Chavez Stefani , Sarro Lucía , Finocchiaro Franco
Published: December 2022

La dimensión social de la arquitectura no ha tenido gran desarrollo, a diferencia de la ambiental y económica. Es por ello que este artículo se plantea como objetivos: (1) analizar la evolución de las publicaciones sobre la sostenibilidad social en la arquitectura, a través de una revisión sistemática de la literatura, y (2) resumir los principales aportes de los trabajos más destacados. A partir del análisis bibliométrico, se puede identificar que se trata de una temática de estudio actual: al considerar el total de trabajos existentes sobre la dimensión social de la arquitectura, se encontró que el 75 % han sido publicados en los últimos siete años. Por su parte, al efectuar el análisis de contenido, se detectan tres aristas o temáticas de importancia a la hora de definir la arquitectura sostenible en sus aspectos sociales: la participación ciudadana, la cultura y la accesibilidad. También, se identifican distintos indicadores y herramientas diseñadas desde la administración que pueden contribuir a su medición y monitoreo.
TINGKAT PENERIMAAN DAN NILAI GIZI NUGGET IKAN CAKALANG DENGAN PENAMBAHAN DAUN BAYAM HIJAU
Authors: Bumulo Nur Iin , Hadi Novian Swasono , Setiawan Denny Indra , Domili Indra , Talibo Sofyawati D.
Published: December 2022

Skipjack  is a medium-sized fish from the skombride family and  the only species from katsuwonus genus, and it contains macro and micro minerals contain  needed by body. The minerals in skipjack includes K, Na, Ca, Fe, Cu, and Zn. Also, the fish contains good nutrientl content such as omega-3, omega-6, iron, vitamin A, D, E, B1, B6 and C. This research aims at finding out the preference level and nutritional value of skipjack nuggets with the addition of green spinach leaves for 10gr, 20gr and  30gr. Method applied in the research is organoleptic test with Friedman test and Wilcoxon test. The research data are collected by using  organoleptic test. The results of preference level indicated that the most preferred test by panelist is treatment I with average value of 2.88,  the most preferred aroma of skipjack nugget by panelist is in  treatment 2 with average value of 2.92,  the most preferred texture of skipjack nugget by panelist is in  treatment 2 with average value of 2.92 and the highest nutritional value  found in treatment 3 with value of  4.8 for energi,  0.27 for protein,   0.12 for fat and  0.87 for carbohydrate. To sum up, the most preferred skipjack nugget, reviewed from taste, color, aroma and texture, is in treatment2 (addition of 10 grams of skipjack. Ikan cakalang adalah ikan berukuran sedang dari familia skombride (tuna) satu-satunya spesies dari genus katsuwonus.Ikan cakalang memiliki kandungan mineral makro dan mikro yang sangat dibutuhkan oleh tubuh. Jenis mineral yang terkandung dalam ikan cakalang yaitu K, Na, Ca, Fe, Cu, dan Zn dan ikan cakalang memiliki kandungan gizi yang baik di antaranya omega-3, omega-6, zat besi, vitamin A, D, E, B1, B6 dan C. Penelitian ini bertujuan untuk mengetahui tingkat penerimaan dan nilai gizi nugget ikan cakalang dengan penambahan daun bayam hijau 10gr, 20gr, 30gr. Metode penelitian yang digunakan yaitu uji organoleptik dengan uji friedman test/perengkingan dan uji Wilcoxon. Pengumpulan data dilakukan dengan menggunakan form uji organoleptik. Hasil tingkat penerimaan nugget ikan cakalang terhadap rasa yang paling banyak disukai panelis yaitu pada perlakuan 1 nilai rata-rata diperoleh 2,88 untuk warna nugget ikan cakalang yang paling banyak disukai panelis yaitu pada perlakuan 1 dengan nilai rata-rata 2,92 untuk aroma nugget ikan cakalang yang paling banyak disukai panelis yaitu pada perlakukan 2 dengan nilai rata-rata 2,92 untuk tekstur nugget ikan cakalang yang paling banyak disukai panelis yaitu pada perlakuan 2 dengan nilai rata-rata 2,95 dan nilai gizi yang tertinggi yaitu ada pada perlakuan 3 dengan energi 4,8 protein 0,27 lemak 0,12 karbohidrat 0,87. Kesimpulan dari penelitian ini yaitu nugget ikan cakalang yang paling banyak disukai ditinjau dari rasa, warna, aroma dan teksturnya itu pada nugget jantung pisang dengan perlakuan 2 (penambahan ikan tuna 10 gram).