bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep Ensemble Learning for Rapid Large-Scale Post-Earthquake Damage Assessment---Application to 2023 Kahramanmaraş Earthquake Sequence
Authors: Soleimani-Babakamali Mohammad Hesam , Askari Mohammad , Heravi Mohammad Ali , Sisman Rafet , Attarchian Nahid , Askan Aysegul , Soleimani Rojiar , Taciroglu Ertugrul
Published: October 2023

Extensive impacted region and government damage surveys following the 2023 Kahramanmaraş earthquake sequence provided a unique opportunity to design and validate a rapid post-event damage assessment framework with satellite images, addressing the typical challenges (e.g., generalization to unseen areas) encountered in rapid regional assessment efforts. By analyzing images from the significantly impacted city of Antakya, we manually identified visual features and compared those with damage states in the survey. Then, an Artificial Intelligence-based framework was developed to automate segmentation and damage assessment processes for future test areas. The resulting tool, dubbed RAPID-A, is an uncertainty-aware ensemble of various deep segmentation models fed with public data released shortly after such incidents. Furthermore, the extent of the damages reported in the survey allowed us to propose and validate a strategy to identify various intensities of damage using a single model, considering the less severe damage as more uncertain. Test case studies in Gaziantep and Kahramanmaraş demonstrate that RAPID-A is generalizable, accurate, and efficient. The significance of this framework lies in its ability to assist in rapid initial damage evaluations before expert dispatch or to replace it in countries that lack the capacity to launch large-scale regional assessment programs to guide foreign support.
Hybrid Attention-Based Shifted Graph Convolutional Networks
Authors: Liu Bo , Guoping Wang , Aihua Zhang , Liu Xiaoqun , Zhiyin Han
Published: October 2023

[1]Aiming at the problem that the existing algorithms for recognizing human actions in videos will be affected by changes in the environment or human body posture, a mixed-domain attention channel is designed using channel attention and spatial attention mechanisms to optimize the feature data input by the network. Use the mixed attention mechanism to detect specific parts and increase the proportion in the skeleton map, thereby improving the accuracy of action recognition. Secondly, using the shift operation to replace the conventional convolution operation in the space-time convolution graph can obtain a convolution effect that is more efficient, has fewer parameters, and has a larger receptive field. This paper conducts experiments on the NTU RGB-D dataset, and the recognition accuracy of human actions on the X-Sub subset reaches 94.5%.
[1]This work was supported by the Natural Science Foundation of Hebei Province (hky22027).
AuthorResume: Liu Xiaoqun (1968-), male, Zhangjiakou, Hebei Province, professor, master director, main research interests: computer network and information security.
Bioinformatics analysis revealed the potential crosstalk genes and molecular mechanisms between intracranial aneurysms and periodontitis
Authors: Huang Jian-huang , Chen Yao , Kang Yuan-bao , Yao Zheng-jian , Song Jian-hua
Published: October 2023

Objectives
The risk of intracranial aneurysms (IAs) development and rupture is significantly higher in patients with periodontitis (PD), suggesting an association between the two. However, the specific mechanisms of association between these two diseases have not been fully investigated.
Materials and Methods
In this study, we downloaded IAs and PD data from the Gene Expression Omnibus. Differentially expressed genes (DEGs) were identified, and functional enrichment analysis was performed. The protein-protein interaction (PPI) network and weighted gene co-expression network analysis (WGCNA) was performed to identified key modules and key crosstalk genes. In addition, the immune cell landscape was assessed and the correlation of key crosstalk genes with each immune cell was calculated. Finally, transcription factors (TFs) regulating key crosstalk genes were explored.
Results
127 overlapping DEGs were identified and functional enrichment analysis highlighted the important role of immune reflection in the pathogenesis of IAs and PD. We identified ITGAX and COL4A2 as key crosstalk genes. In addition, the expression of multiple immune cells was significantly elevated in PDs and IAs compared to controls, and both key crosstalk genes were significantly negatively associated with Macrophages M2. Finally, GATA2 was identified as a potential key transcription factor (TF), which regulates two key crosstalk gene.
Conclusions
The present study identifies key crosstalk genes and TF in PD and IAs, providing new insights for further study of the co-pathogenesis of PD and IAs from an immune and inflammatory perspective. Also, this is the first study to report the above findings.
One-Year Outcomes in Patients Who Survived COVID-19-Related Acute Respiratory Distress Syndrome (ARDS): Pulmonary Function Tests (PFTs), Oxygen Requirement, and Quality of Life (QoL)
Authors: Arfoosh Rami , Nisbet Rachel , Nguyen Kimtuyen , Herrera Martin , Kim Nathanial , Abiodoye Oluseyi , Jones Louise
Published: October 2023

Background: The COVID-19 pandemic saw ARDS, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), emerge as a predominant factor in patient mortality and morbidity. This study sought to gauge the first-year outcomes of survivors of COVID-19-induced ARDS in terms of pulmonary function, liberation from oxygen and QoL.Methods: We retrospectively screened 492 patients and analyzed 29 patients from our pulmonary clinic who had post-COVID-19 ARDS. We assessed data points around the 3, 6, and 12-month marks, specifically focusing on pulmonary function, oxygen requirement and QoL using the 36-Item Short Form Survey (SF 36) questionnaire.Results: Our cohort predominantly consisted of middle-aged males, with none having required invasive mechanical ventilation during their hospitalization. By the 3-month mark, a significant portion displayed reduced diffusion and restrictive patterns, with an ongoing oxygen requirement. Notably, all PFT parameters - diffusion, Forced Vital Capacity (FVC), and Forced Expiratory Volume in 1 second (FEV1) - registered improvement over the course of a year, with most of these enhancements becoming evident by the 6-month period. Both FEV1 and FVC approached normative values by the year's end. Diffusion capacity, despite marked enhancement, remained slightly abnormal at the 12-month evaluation. The proportion of patients on supplemental oxygen also dwindled considerably from 3 to 12 months, with significant reductions already observable at 6 months. Interestingly, while the SF 36 assessment for QoL did not evince consistent improvements across the board, social functioning was an exception, improving over the one-year span. The study began with participants holding an average SF 36 general health score of 63, compared to the population norm of 72.Discussion: Survivors of COVID-19 ARDS, who didn't necessitate invasive mechanical ventilation, demonstrated significant lung function recovery and a decreasing dependence on oxygen supplementation over a year's duration. However, the SF 36 QoL scores remained relatively static, potentially indicating the impact of non-pulmonary factors on QoL.
Shaping the Professional Behaviour of Junior Physiotherapists by their Communication Style. Implications on the recovery process of patients
Authors: Urea Ionela Roxana
Published: October 2023

Purpose: This study approaches a penetration into the basic or derived processes connected with the wish to analyse, among young physiotherapists, how communication style shapes professional behaviour for enhancing their professional style for efficiently dealing with patients during the therapeutic process.
In our study, we had 135 Romanian junior physiotherapists as participants. We used: a) Questionnaire SC (Analysis of Communication Style) adapted by the researcher in 2017 for physiotherapists (index fidelity =. 765, test-retest index= .749); b) Questionnaire of psychotherapists' professional behaviour’ features created by the researcher in 2018 (index fidelity =. 775, test-retest index= .739).
Results: The communication style manages the junior physiotherapists' professional behaviour during the therapeutic relationship with the patient and his family and the professional climate. It has several implications and several effects on current activities.
Reconstructing the Phylogeny of Calliandra sect. Androcallis (Fabaceae): Insights from the Inclusion of Colombian Species, with a Focus on the Enigmatic Taxon Calliandra medellinensis
Authors: Arias Tatiana , Saldarriaga Juan David , Arenas-Castro Henry , Idarraga-Piedrahita Alvaro , Lopez-Alvarez Norberto , Luque Eduardo Tovar , Torres-Morales German , Gonzalez Mailyn A , Soto-Calderon Ivan Dario
Published: October 2023

Phylogenetic relationships for the genus Calliandra section Androcallis (Fabaceae) were reconstructed, including previously sequenced species from Central and South America and unexamined species from Colombia, one of Calliandra main diversity centers. Here, we generated novel DNA sequences of Calliandra species from Colombia for the nuclear Internal Transcribed Spacer (ITS) and the chloroplast trnL and trnL-F intergenic spacer. By incorporating a broader taxonomic sampling, the relationships among main clades in Androcallis were clarified, providing a systematics framework in which to test evolutionary hypotheses. Phylogenetic analysis recovered five well-supported clades within Androcallis. Most species within each clade had similar geographical distributions and relationships between the five major clades are strongly supported for the first time. However, core Androcallis relationships, including most species from Colombia sequenced here, remain unclear. A second goal of this study was to determine the taxonomic status of Calliandra medellinensis. This enigmatic taxon emblematic of Medellín, Colombia, is found in limited numbers within the Aburrá Valley and has been proposed to be a hybrid taxon. Here, C. medellinensis, C. magdalenae and C. haematocephala were not monophyletic within the core Androcallis clade. This suggests that C. medellinensis could potentially be an interspecific hybrid between C. magdalenae and C. haematocephala, thus challenging the taxonomic status of this species; however, more informative molecular markers should be used in future studies. Specifically, genomic studies should assess interspecific hybridization demographic models. Such insights can illuminate the C. medellinensis origin, guiding conservation strategies and providing valuable evolutionary overviews.
Insecticidal effects of substances from cinnamon bark – eugenol, trans-cinnamaldehyde and cinnamaldehyde to yellow mealworm
Authors: Dzięgelewska Aleksandra , Lubawy Jan , Adamski Zbigniew
Published: October 2023

The use of synthetic pesticides is limited due to increasing environmental pollution and developing pest resistance, as well as the increasingly confirmed negative impact of these compounds on human health. At the same time, the demand for food grown in the spirit of organic farming is increasing. Therefore, as part of Integrated Plant Protection (IPM), biopesticides are used, i.e., substances of natural origin that are characterized by low toxicity to non-target species and easy availability. Such substances include, among others, compounds found in the bark of the Ceylon cinnamon tree (Cinnamomum verum J.Presl), such as eugenol, trans-cinnamaldehyde and cinnamaldehyde. However, the mechanism of their action has not been sufficiently researched. Therefore, this study presents the results of the impact of these compounds on the important pest of cereal crops and food stores, and - at the same time - a model organism - Tenebrio molitor beetle. The tested compounds were administered by injection, inhalation, with food or one of two contact routes: by immersing the tested larvae or by contacting them with substratum soaked in an appropriate solution of the tested compound. The results allowed us to determine the LT50 parameter, and the probit analysis carried out the LC20/30/50/95 values. The obtained results also allowed to conclude that the most effective route of administering cinnamon bark compounds is contact and injection, and the most effective is eugenol. The impact of the tested compounds on the morphological malformations of T. molitor larvae was also documented and discussed.
Higher Fluid and Lower Caloric Intakes: Associated Risk of Severe Bronchopulmonary Dysplasia in ELBW Infants
Authors: Stonestreet Barbara , Kolitz Danielle , Przystac Lynn , Tucker Richard , Oh William
Published: October 2023

Objective
To examine nutritional intake profiles and growth trajectories of extremely low birth weight (ELBW) infants who develop severe bronchopulmonary dysplasia (BPD).
Study Design
Case-control study using multiple logistic regression analysis with generalized estimating equations (GEE) to adjust for matching.
Results
Cumulative and mean fluid intakes were higher (p=0.003) and caloric intakes lower (p<.0001)through week two in infants who developed severe BPD (n=120) versus those without severe BPD (n=104). Mean caloric intake through week 12 was lower in infants who developed severe BPD (102±10.1 vs. 107±8.5 kcal/kg/day, p<0.0001). In logistic regression models, lower mean caloric intake through week 12 was associated with increased risk of developing severe BPD. Linear growth reduced the odds of BPD by ~30% for each Z-score point.
Conclusions
Higher fluid and lower total caloric intakes and reductions in linear growth were independently associated with an increased risk of developing severe BPD in ELBW infants.
Hybrid Off-Grid Energy Systems Optimal Sizing with Integrated Hydrogen Storage Based on Deterministic Balance Approach
Authors: Selim Alaa , El-shimy Mohamed , Amer Ghada , Ihoume Ilham , Masrur Hasan , Guerrero Josep M.
Published: October 2023

Incorporating diverse renewable energy sources is imperative for establishing a resilient and sustainable power infrastructure. This research explores the optimal techno-economical hybrid energy system configuration, emphasizing hydrogen energy for system balance. We introduce a novel DBM (Deterministic Balanced Method) to ascertain the annual energy output over the project’s lifespan, contrasting it with HOMER software results. Validation against HOMER Pro revealed a high consistency in our method, with differences within a 5% range. This indicates our approach’s reliability in determining hybrid energy system sizes accurately. In addition to harnessing solar radiation and wind data from NASA and METEONORM, our study encompasses a real-case evaluation of Cairo International Airport’s hybrid renewable energy systems. The system design is based on actual, researched loads. Our results not only offer insights into effective hybrid energy system sizing but also propose using surplus energy in distributed networks for industrial and transportation energy conversion applications.
The influence of deep oscillation on early physiotherapy results and inflammatory markers in patients after reconstruction of the anterior cruciate ligament of the knee joint
Authors: Oestervemb Katarzyna , Szczygieł Elżbieta , Kita Bartłomiej , Szczygielska-Babiuch Anna
Published: October 2023

Introduction: ACL anterior cruciate ligament rupture is one of the most common effects of sports knee injuries. Arthroscopic treatment is the least invasive type of surgery that restores the normal function of the ligament and the kinematics of the knee joint. Early introduced physiotherapy is the last stage of this treatment, which allows you to quickly regain mobility.
Aim of the study: To evaluate the influence of deep oscillation on the early results of physiotherapy and on the activity of selected indicators of vascular inflammation and embolism in patients after reconstruction of the anterior cruciate ligament of the knee joint.
Methods: The study involved 60 patients divided into 2 groups: study (N = 30) and control (N = 30). In the study group (GB), the knee joint was additionally deeply oscillated. The mean age of the examined people was 32.7±6.5 years. Women constituted 26.6% of the respondents, and men 73.3%. Measurements of the pain level (VAS scale and algeimeter), the range of motion of the knee joint, the extent of the swelling as well as the level of inflammatory and thrombotic markers (CPR and D-dimmers) were performed.
Effect of Chewing Gum in reducing Postoperative Ileus after Gastro-duodenal perforation peritonitis surgery: a prospective randomized controlled trial
Authors: MUWEL SANJAY , Suryawanshi Seema , Damde Hari Krishna , Mishra Arpan , Yadav Sanjay Kumar , Sharma Dhananjaya
Published: October 2023

Chewing gum reduces the duration of post operative ileus and early recovery of bowel function following elective abdominal surgery. However, its role has not been studied in cases of gastroduodenal perforation peritonitis; prompting us to conduct this study. Eighty-two patients were randomized into two groups, 39 patients received chewing gum (study group) and 43 patients were in control group. Sensation of hunger, appearance of first bowel sound, passages of flatus and faeces were significantly early in the study group; their hospital stay was also shorter. Chewing gum reduces the duration of post operative ileus in cases of gastroduodenal perforation peritonitis.
Registration number: IEC/2020-23/3359 dated 13-12-2020, Institutional Ethics committee Netaji Subhash Chandra Bose Medical College, Jabalpur, India.
Early Oral Feeding versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair: A Randomized Controlled Trail
Authors: Elshwadfy Mohammed , tobar wael , saqr ahmed , ragab amr , Salah ahmed Mohammed
Published: October 2023

Purpose : the study aim was comparing the benefits of postoperative early versus delayed oral feeding in duodenal ulcer repairs.
Materials and methods
Thy study was a single-center prospective, randomized, controlled trial from January to September 2023 at the Emergency department. The eligibility of patients with suspected perforated peptic ulcers was evaluated.
The patients were divided at random into two groups. the early feeding group patients were permitted to consume an oral diet six hours after surgery. Patients were given a liquid diet after 72 hours in the traditional group. Our primary outcome was hospital stay duration, and our secondary outcomes were recovery parameters and 30-day morbidities. The results were analyzed using version 21 of SPSS.
The Results
Forty-nine patients were included in the early feeding group, while 51 were in the traditional group. Patients in the early group had significantly earlier bowel sound (18.673 7; p 0.001), bowel motion (30.8 12; p = 0.001), fluid diet (14 7; p 0.001), and solid diet (35 17; p 0.001).
LOH was significantly shorter in the early feeding group (3.6 0.6 days; p 0.001(
There was a significant decrease in postoperative morbidity, including superficial SSI (p = 0.002), deep SSI (p 0.02), and pulmonary complications (p 0.0001), in the early versus delayed feeding group. However, there was insignificant difference in leak rates (0/49 vs. 1/51)
Conclusions
Early feeding can be administered safely after duodenal perforation repair. Additionally, it can improve outcomes.
The research was recorded at ClinicalTrials.gov Identifier: NCT06042933.
NK-derived exosome miR-1249-3p inhibits Mycobacterium tuberculosis survival in macrophages by targeting SKOR1
Authors: Ma Fengqian , Wang Xuan , Qiu Zhanghua , Ding Shoupeng , Du Wenya , Dai Yumei , Ma Tao , Yue Linzhi , Wang Guofu , Wang Tao , Geng Ling , Wu Lixian
Published: October 2023

Murine Natural Killer cells were cultivated in vitro to isolate NK-derived exosomes. Subsequent quantification via qPCR confirmed enrichment of miR-1249-3p. Ana-1 murine macrophages were cultured in vitro and subsequently inoculated with Mycobacterium tuberculosis (MTB) strain H37Rv. NK-exo and NK-exo miR-1249-3p were separately applied to the infection model, followed by immunological assays conducted post-48-hour co-culture. Western blot analyses corroborated that NK-exo exhibited exosomal marker proteins Granzyme A (GzmA), Granzyme B (GzmB), and Perforin (PFN), alongside a notable enrichment of miR-1249-3p. Functionally, NK-exo augmented the expression levels of Caspase-9,-8, and − 3, as well as PARP, while attenuating the expression of NLRP3, ASC, and Cleaved-Caspase-1. Furthermore, qPCR demonstrated an up-regulation of Caspase-9, -8, and − 3, along with pro-apoptotic factors Bax and Bid, and a concomitant down-regulation of the anti-apoptotic factor Bcl-2. The expression levels of inflammatory markers ASC, NLRP3, Cleaved-Caspase-1, and IL-1β were concomitantly decreased. ELISA findings indicated diminished levels of TNF-α and ROS secretion. NK-exo miR-1249-3p specifically targeted and attenuated the expression of SKOR-1, engendering up-regulation of apoptosis-associated proteins and down-regulation of inflammation-related proteins, consequently affecting cellular fate.Our empirical evidence substantiates that NK-exo induces macrophage apoptosis, thereby mitigating MTB survival. Furthermore, NK-exo miR-1249-3p directly targets and inhibits SKOR-1 expression, leading to macrophage apoptosis and consequently hampering the proliferation of MTB. The data implicate the potential therapeutic relevance of NK-exo and miR-1249-3p in managing drug-resistant tuberculosis.
Sentiment Analysis on Code-Mixed Tamil-English Corpus: A Comprehensive Study of Transformer-Based Models
Authors: Sangeetha M. , Nimala K.
Published: October 2023

NLP, or natural language processing, is a subfield of AI that aims to equip computers with the ability to understand and analyze human language. Sentiment analysis is a widely used application of NLP, particularly for examining attitudes expressed in online conversations. Nevertheless, many social media comments are written in languages that are not native to the authors, making sentiment analysis more difficult, especially for languages with limited resources, such as Tamil. To tackle this issue, a code-mixed and sentiment-annotated corpus in Tamil and English was created. This article will explain how the corpus was established, including the process of data collection and the assignment of polarities. The article will also explore the agreement between annotators and the results of sentiment analysis performed on the corpus. This work signifies various performance metrics such as precision, recall, support, and F1-score for the transformer-based model such as BERT, RoBerta, and XLM-RoBerta. Among the various models, XLM-Robert shows slightly significant positive results on the code-mixed corpus when compared to the state of art models.
Solar Radiometric Observations and Ionospheric Kinships by Space Overseer(s) at Limb-beaming Landau
Authors: Soomro Riaz A. , Sun Liguo , Ntawangaheza Jean de Dieu , Ali Sajjad , KHUHAWAR Faheem , Ali Waqas
Published: October 2023

Strong varying intensity of solar activities impact near-earth space environments, magnetosphere, ionosphere, thermosphere as well as on the technological systems such as satellite communications, aircraft avionics, electrical power grids, and threats to human lives. Hence, it is essential to measure the phase of solar quietness as well as to monitor total flux using radiometric devices. This paper presents an analysis of Solar Flux and Sudden Ionospheric Disturbances (SID). Additionally, the paper further analyzes three magnetic storms that occurred during a 27-day Bartels period with 3-hour interval indices. These storms include E1 on March 31, 2001, which had a geomagnetically disturbed Kp of 9, and two magnetic storms with Kp ≥ 6 (E2 on April 8, 2001, and E3 on April 11, 2001). The events of 11 days of Solar Flux were observed in April 2001, within the frequency range of (245,15400) MHz with a peak of 143,671 SFU, under the supervision of the National Oceanic and Atmospheric Administration (NOAA). On March 25, 2008, NOAA's active region (AR) 10989 experienced peepholes due to a Coronal Mass Ejection (CME) of the M1.7 class flare. This event was reported chronologically to have a widespread index/imp rating of 5/2.
Study on the mechanism of action of traditional Chinese medicine compound Wu Mei Pill in inhibiting rheumatoid arthritis through TLR4-NF-κB pathway
Authors: Fu Yuheng , Gao Chunyu , Teng Hongbo , Sun Xialin , Zhao Yaru , Zhang Wenxin , Li Siwen , Huang Liang , Fan Bowen , Zhao Yan , Zhang Haibo
Published: October 2023

Background
Wu Mei Pills (WMP) is a traditional Chinese medicine compound with good anti-inflammatory effects. It is used in Chinese medicine theory to treat diseases such as wind, cold. Rheumatoid arthritis (RA) belongs to the “Bi” syndrome caused by wind and cold in traditional Chinese medicine. WMP has been documented for treating RA, but its mechanism of action on RA is still unclear.
Aim of the study
This experiment mainly explores the mechanism of WMP on collagen-induced rheumatoid arthritis model in rats (CIA rat), as well as the mechanism of inflammation, migration and invasion of fibroblasts like synovial cells (RA-FLS).
Materials and methods
Analyze the chemical composition of WMP through UPLC-MS. Then, the intrinsic mechanism of WMP was analyzed by ELISA, cell scratch, Transwell, and Western blotting. Finally, WMP was applied to CIA rats to further explore the mechanism of WMP inhibiting RA.
Result
The UPLC-MS results indicate that WMP contains 181 compounds. Serum containing WMP (2%, 8%) plays an important role in inhibiting the migration and invasion mechanisms of RA-FLS. The intrinsic mechanism is to decrease matrix metalloproteinases (MMP-2) and MMP-9 and increase the protein expression of their complexes TIMP-1, TIMP-2 in RA-FLS. At the same time, WMP also reduced TNF and IL-6 levels in RA-FLS- α, acting through inhibition of TLR4-NF-κB inflammatory pathway activation. In in vivo experiments, WMP (0.5g/kg, 2kg/kg) alleviated arthritis and immune organ indices in type II collagen-induced rheumatoid arthritis model-CIA rats. Pathological section results showed that WMP suppressed knee joint swelling and inflammatory infiltration in CIA rats.
Conclusions
WMP plays a significant role in alleviating the course of RA. The specific mechanism is to inhibit the classical TLR4-NF-κB inflammatory pathway and reduce the secretion of inflammatory factors in the serum of RA -FLS and CIA rats. In addition, it regulates the dynamic balance of MMP-2/TIMP-2, MMP-9/TIMP-1, modulates the mechanism of RA-FLS invasion, and protects articular cartilage tissues in RA.
Roof Movement and Instability Fracture Characteristics in Shallow-Buried Thin Coal Seam Conventional Mining Faces
Authors: Zhang Jihua , Rui Qiao , Yang Yushun , Chen Jiarui , Shen Wei , Yuan Yue , Wang Chengwu , Liu Weili
Published: October 2023

The variation in the width of the mining face significantly affects the stability of the face, leading to potential roof fracturing and collapse. Additionally, strong coal and rock pressure can manifest, severely impeding the safe production of coal mines. This study uses the 16705 conventional working faces of Jinda Coal Mine as its engineering background to investigate the characteristics of roof strata movement and instability under conditions of variable-width mining in shallow-buried thin coal seams. First, using the key strata theory, the study estimates the dynamic load of the roof strata. Next, a mechanical model analysis of the roof strata movement in the working face is presented. This analysis shows the impact of different dimensions of the overhanging plate structure and residual overhanging structures in the corner on roof movement and its associated fracture mechanics. The findings indicated that as the roof width increases, the maximum bending deformation, deformation moment, and deformation stress rise logarithmically. Similarly, with an increased overhanging span of the roof, these metrics increase exponentially. In addition, as the size of the residual overhanging structures in the corner grows, these parameters rise linearly. Finally, this study analyzes the effect of roof instability on overlying pressure and estimates both the initial fracture step length and cyclic movement fracture step length of the roof. These insights offer valuable scientific guidance and a theoretical foundation for analyzing the adaptability of load-bearing pillars pressure in thin coal seam mining faces, bearing significant relevance to safety production.
Rate, Causes, and Predictors of Readmission within 60 Days Following Total Laryngectomy
Authors: Rammal Almoaidbellah , Alqutub Abdulsalam , Alsulami Omar , Mozahim Naif , Mozahim Sara , Awadh Mohammed , Hakami Muatasaim , AlThomali Rahaf , Mogharbel Ahmed
Published: October 2023

Background:
The readmission rate is a metric for quality of care. Total laryngectomy (TL) is a complex procedure, and patients undergoing TL are at high risk for readmission, which exposes them to hospital-acquired complications. We aimed to identify the rate, causes, and predictors of hospital readmission within 60 days after discharge following TL.
Methods:
In this retrospective study, we included all patients undergoing TL in a single tertiary care center between 2008 and 2022. Patient charts were reviewed for demographics, comorbidities, and causes for readmission.
Results:
Of 83 patients who underwent TL, 12 (14.5%) were readmitted within 60 days. Common causes were surgical site infection (33.33%) and mucocutaneous fistula (25%). Significant predictors for readmission were tobacco use (P = 0.003), African ethnicity (P = 0.004), being unmarried (P < 0.001), lower preoperative serum albumin (P < 0.001), higher preoperative TSH (P = 0.03), higher preoperative neutrophil count (P = 0.035), higher American Society of Anesthesiology (ASA) score (P = 0.028), and higher Cumulative Illness Rating Scale (CIRS) score (P = 0.029).
Conclusion:
The rate of readmission after total laryngectomy was 14.5%. Frequent causes include wound infection and fistulas. Predictors include preoperative hypoalbuminemia, hypothyroidism, African ethnicity, being unmarried, tobacco use, and a higher baseline burden of comorbidities. Such factors can be targeted to reduce hospital readmission rates.
Repeatability and reliability of the Kinefis Podia plantar pressure platform.
Authors: Sánchez-Valero Clara , Corral-Liria Inmaculada , Jiménez-Fernández Raquel , Casado-Hernández Israel , López-López Daniel , Navarro-Flórez Emmanuel , Pérez-Boal Eduardo , Martínez-Jiménez Eva María , Palomo-López Patricia
Published: October 2023

Introduction: Abnormal plantar pressures are the distinguishing feature of various pathological conditions and abnormalities. For accurate and rapid detection of patients and as an aid to correct treatment we use pressure platforms. Therefore, it is essential to evaluate the reliability and repeatability of these devices before making clinical decisions to be sure of our results. The purpose of this study was to determine the reliability of the Kinefis Podia platform in static and dynamics.
Material and methods: To determine the reliability and repeatability of the Kinefis Podia platform for the study of plantar pressures in statics and dynamics parameters forty-seven healthy individuals stood and walked on the pressure platform. Three measurements were recorded with each foot in statics and dynamics position and two sessions were performed. The data obtained were several variables of interest for inter-session reliability were calculated using intraclass correlation coefficients (ICC), standard error of measurement (SEM), percentage error and coefficient of variation (CV).
Results: Reliability and intersession between static and dynamic sessions produced moderate to excellent CHF, low SEM, low percentage errors, and low CV. Static trials had higher ICCs, lower error rates, and lower CVs compared to dynamic trials. Inter-session reliability also had higher ICCs, lower percentage errors, and lower CVs compared to inter-session reliability.
Conclusion: This study demonstrates that the Kinefis Podia platform is a reliable and reproducible device to collect footprint pressures. Static tests produce better reliability, probably due to the inherent great variability during dynamic running. These results can be used as a basis for future studies and to determine a priori sample sizes for research using the Kinefis Podia Platform.
2023 Turkey-Syria Earthquakes: Analysis of pediatric victims admitted to a tertiary center
Authors: Döven Serra Sürmeli , Tezol Özlem , Yeşil Edanur , Durak Fatma , Mısırlıoğlu Merve , Alakaya Mehmet , Karahan Feryal , Kıllı İsa , Akça Mehtap , Erdoğan Semra , Can Mevlüt , Delibaş Ali
Published: October 2023

Background: On February 6th, 2023, two consecutive earthquakes occurred in southeastern Türkiye, of which the epicenter for both was Kahramanmaraş, with magnitudes of 7.7 and 7.6, respectively. Herein, it was aimed to analyze the clinical and laboratory findings, and management of pediatric victims admitted to our center.
Methods: Patients who were admitted to our center after the earthquakes were included in the study. Clinical and laboratory characteristics of the patients were taken from their records.
Results: Included in the study were 649 pediatric earthquake victims. Acute kidney injury (AKI) was observed in 16 patients. White blood cell count (15624.06 ± 7964.67, 11807 ± 1.93 × 103/mL, P < 0.001), creatinine (0.76 ± 1.04 vs. 0.42 ± 0.52 mg/dL, P = 0.021), and C-reactive protein (74.00 ± 76.96 vs. 19.70 ± 38.94 mg/L, P < 0.001) levels were higher, while the sodium (133.78 ± 5.38 vs. 136.67 ± 5.41 mEq/L, P < 0.001) levels were lower in the patients with Crush Syndrome (CS) compared to the non-CS patients. Intravenous fluid replacement was administered to the patients with CS at a dose of 4000 cc/m2/day. Hypokalemia was observed in 51.9% of the CS patients on the third day. All of the patients with AKI ameliorated and no deaths occurred.
Conclusions: Hyponatremia and an increase in inflammation markers may be observed associated with CS. Hypokalemia may be seen as a complication of vigorous fluid therapy during hospitalization. Early fluid replacement therapy is essential to prevent the development of AKI in patients with CS.
Study on performance of passive flexible device based on tube-piercing machine of tubular heat exchanger
Authors: Gai Chao hui , Gao Ze yu , Wang Cheng Gang
Published: October 2023

This article analyzes the conditions for the assembly of pipes through rough inner walls of axial holes without jamming and designs a passive-compliant device based on repulsive magnetic forces to solve the jamming issue encountered during the assembly of copper pipes and axial holes. In the passive-compliant device, two repulsive magnetic forces are placed internally. During the assembly process, the end effector is separated from the axial hole, and the torque generated by the rotational push-pull of the passive compliant device is used to overcome the jamming point and quickly return to its original position. By measuring the magnitude of the force using a force sensor at the end of the axial hole, experiments were conducted on axial holes with different offset angles and clearances. The results indicate that there is a gap between the copper pipe and the inner wall of the axial hole. When the offset angle is less than 15° and the axial hole clearance is smaller than 5.5mm, the copper pipe can effectively and quickly pass through the axial hole. With the damping coefficient k set to 0.1, the assembly time can be effectively shortened to no more than 7.2 seconds without affecting the ability of the copper pipe to overcome the jamming phenomenon. This article conducted numerical simulations of the piercing process and analyzed that the controlled range of offset angles is between 15° and 21°, while the controlled range of the clearance within the axial hole is between 5mm and 14mm. These parameters enable overcoming the jamming phenomenon and facilitate effective pipe insertion.
Numerical investigation on the behaviors of railway embankment under normal faulting
Authors: Chen Haohua , Liu Jiankun , Li Zhijian , Liu Xiaoqiang , Nan Jiyun , Liu Jingyu
Published: October 2023

Active faults in the earthquake region are consistently regarded as a potential geological hazard to the construction and operation of railway engineering. However, crossing active faults is always difficult to be avoided for railway construction. In this paper, three-dimensional finite element models are established to study the behaviors of the railway embankment under normal faulting. The constitutive model used in the soil layer is validated by using the data of the centrifuge tests from the existing paper. A series of parametric studies are conducted considering the faulting offset, the thickness of the soil layer, the dip angle of the fault and the cross-fault angle of the embankment. Emphasis is given to (1) the affected zones; (2) the vertical displacement, the longitudinal slope, the lateral displacement, and the radius of the curvature of the embankment centerline; (3) the potential regions where the fault ruptures outcrop based on the plastic strain; (4) the stress characteristic of the embankment surfaces. The analysis shows that the increase of faulting offset would increase the value of longitudinal slope in the cross-fault region of the embankment. The existence of soil layer and its thickening would widen the affected zones and the regions where the fault ruptures outcrops. The fault dip angle and the cross fault angle of the embankment have a complex effect on the behaviors of the crossing embankment. The depth of the subsidence zone of the embankment would increase with the decrease of fault dip angle and the large fault dip angle would change the primary fault rupture to be a compressive one directly above the fault line. If the embankment crosses the fault line obliquely, the curvature radius of the centerline would hardly meet the design code.
Development of a Momentum Exchange Coefficient Model for Continuum to Rarefied Planar Laminar Gas Flows
Authors: Alshareef Sultan , Harman Todd , Ameel Tim
Published: October 2023

Gaseous flow in micro-scale systems comprised of moving components experience Fluid-Structure Interaction (FSI) and rarefaction when the length scales are small. While many commercial codes claim the ability to simulate FSI problems, such a combination is very challenging to model. Here we propose a momentum exchange coefficient model within the FSI algorithm, MPM-ICE, that enables the simulation of rarefied flow. The proposed model was derived using the Maxwell first-order velocity slip boundary condition. The model is verified using analytical solutions for pressure-driven Poiseuille and Couette planar flow. In addition, the model is validated using experimental pressure data of microchannel gas flow and DSMC simulation results. Unlike the previous model, the proposed model is more robust and is nearly insensitive to the grid size and the solid particle distribution around the surface. In addition, the model is universal since it is applicable for flow in the continuum and slip regimes.
Mutually beneficial FAB consortia fortify stress resistance of Euglena mutabilis: evidence from sequencing, antibiotics, and Cd challenges
Authors: Kaszecki Emma , Palberg Daniel , Grant Mikaela , Griffin Sarah , Dhanjal Chetan , Capperauld Michael , Emery R. J. Neil , Saville Barry J.
Published: October 2023

Background
Synthetic algal-fungal and algal-bacterial cultures have been investigated for technological applications because the microbe interactions enhance growth and improve stress tolerance of the co-cultures. Yet these studies often disregarded natural consortia due to the complexity of environmental samples. The protist Euglena mutabilis is found in association with other microbes in acidic environments with high heavy metal (HM) concentrations. This may suggest that microbial interactions are essential for the alga’s ability to tolerate these extreme environments. Our study assessed the Cd tolerance of a natural fungal-algal-bacterial (FAB) association where the algae is replaced by the photosynthetic protist E. mutabilis.
Results
This study provides the first assessment of antimycotic and antibiotic agents on E. mutabilis. Our results indicate that suppression of associated fungal and bacterial partners significantly decreases the number of viable E. mutabilis cells upon Cd exposure. However, axenic Euglena gracilis recovered and grew well following antibiotic treatments. Interestingly, both Euglena species displayed increased chlorophyll production upon Cd exposure. Finally, the constituent organisms in the E. mutabilis FAB consortia were identified using PacBio sequencing to be a Talaromyces sp and Acidiphilium acidophilum.
Conclusion
This study uncovers a possible tripartite symbiotic relationship, a FAB consortia, that withstands exposure to high concentrations of HM. This unique fungus, bacterium, and E. mutabilis interaction strengthens the photobiont’s resistance to Cd and provides a model for the types of FAB interactions that could be used to create a self-sustaining bioremediation technology.
A Comparative Study of "Internet +" Case-based Learning and Traditional Case-based Learning in an Integrated Instructional Mode
Authors: Wang Xinqi , Wang Jiale , Hu Haoyuan , Zhao Jiahui , Wang Songyun
Published: October 2023

Objective To study the difference between "Internet +" case-based learning (CBL) and traditional CBL in the clinical pathophysiology and therapeutic (CPPT) teaching mode and to provide a foundation and basis for medical teaching reform.
Methods In August 2022, fourth-year students of the First Clinical College of Wuhan University received a "Learning Experience" survey to evaluate the teaching satisfaction and learning harvest of both CBL methods.
Results Overall, "Internet +" group has higher scores in both teaching satisfaction and learning harvest. "Internet +" CBL can improve students' ability to utilize knowledge, collect information and work as a team. However, traditional CBL might reduce the study burden, provide more spare time, and challenge their ability of self-discipline.
Conclusion Under the CPPT teaching mode, "Internet +" CBL are superior to traditional CBL in different degrees. The "Internet +" CBL promising to be put into practice as a new educational mode, but with attention to the issue of learning burden.
Software Reliability Growth Model Selection by using VIKOR Method Based on q-Rung Orthopair Fuzzy Entropy and Distance Measures
Authors: Mateen Farhan , Munir Asim , Nadeem Muhammad
Published: October 2023

Several software reliability growth models (SRGMs) have been proposed in recent years to predict the reliability of software measures such the number of remaining defects, the failure rate of the program, and the dependability of the software. Since they rely on a small set of model selection criteria, the tools and approaches for choosing robust software models found in the literature cannot be employed with great confidence. A crucial challenge is how to prioritize software reliability growth models (SRGMs) using multi-attribute decision-making (MADM). Ultimately, ambiguities and uncertainties in any MADM approach are critical problems. To overcome this, numerous notions and approaches were investigated and a q-Rung orthopair fuzzy set (q-ROFS) is one of the most significant and impressive tools to manage ambiguities and uncertainties. Thus, in this article, for the prioritization of SRGMs, we first, investigate entropy measures (EMs) in the environment of q-ROFS and prove its associated properties. We also investigate tangent distance measures in the setting of q-ROFS and prove the linked properties. After that, we interpret a VIKOR approach in the setting of q-ROFS based on the investigated measures to tackle MADM problems. Through this VIKOR approach in this article, we exhibit the prioritization of SRGMS with the assistance of a numerical example. In order to show that the suggested approaches are more effective and beneficial than the current methodologies, a numerical example of the proposed methodology is shown, along with a detailed comparison of the investigated models with some of the existing methodologies.
Antibiotic Prescribing Patterns in Pediatric Patients using the WHO AWaRe Framework in a Quaternary Hospital in Nampula, Mozambique
Authors: Xavier Sancho Pedro , Silva Ageo Mario Candido Da , Victor Audêncio
Published: October 2023

Background:Antibiotics are often prescribed inappropriately, either when they are not needed or with an unnecessarily broad spectrum of activity. This is a serious problem that can lead to the development of antimicrobial resistance (AMR). This study was conducted to assess the antibiotic prescribing pattern in pediatric patients hospitalized at a quaternary hospital in Nampula, Mozambique, using the WHO indicators and Framework as a reference.
Methods:A cross-sectional study with a quantitative approach was conducted in 2020. The population consisted of children aged 0-10 years hospitalized in a ward of a quaternary-level hospital in Nampula, Mozambique. The prescription pattern was assessed using indicators and the WHO classification of antibiotics into AWaRe categories. Descriptive statistics were applied.
Results:A total of 464 antibiotics were prescribed during the study. The age group of 1-3 years and 28 days-12 months were prescribed more antibiotics. The most common antibiotics were ceftriaxone and crystallized penicillin, which were frequently prescribed for patients suffering from bronchopneumonia, gastroenteritis, and malaria. 74.8% of the antibiotics prescribed belonged to the Access group, while 23.7% belonged to the Watch group. There were no prescriptions of antibiotics from the Reserve group. The average number of antibiotics per prescription was 1.51 (SD ± 0.725). The percentage of antibiotic prescribing was 97.5%, with 96.20% by injection. All antibiotics prescribed were on the essential medicines list and prescribed by generic name.
Conclusion: These results are concerning and highlight the urgency of strengthening antimicrobial optimization measures, as well as implementing the AWaRe framework in antibiotic prescribing as an essential strategy to combat AMR.
Pseudo-color infrared and visible image fusion based on attention-dense network
Authors: Qi Jianhuan , Ni Bo , Zhou Xiaoyan , Ni Haibin , Yang Lingsheng , Chang Jianhua
Published: October 2023

In the existing infrared and visible image fusion algorithms, the texture details of the fused image are not clear, and the display of infrared information and texture details is unbalanced. In this paper, we come up with an image fusion method of pseudo-color infrared and visible images based on attention-dense network. Firstly, the gray infrared image is processed by pseudo-color, and then then it is fused with the color visible image. Secondly, during the training process, a generator network structure composed of convolutional layers and dense connected blocks with attention modules is designed. It focuses on the key information of source images and enhances the ability of the network to obtain the information of the source image. Finally, the content loss function is constructed by using infrared pixels, visible pixels, visible gradient and infrared gradient to keep the stability of infrared target and texture details in the fused image. The comparison experiments with five fusion methods are carried out. They show that the proposed fusion method is significantly improved compared with other fusion methods.