bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Student Worksheets Based Inquiry using PhET Simulations to Enhance the Curiosity Attitude of High School Students
Authors: Jarlis Roni , Supriyanti Juli , Syuhada Fildza Arief , Ananto Ananto , Taufiqqurahman Taufiqqurahman , Putri Santi Diana , Rahmi Putri
Published: August 2023

The research aims to develop inquiry-based worksheets which are expected to increase students' curiosity about gas kinetic theory material. The inquiry approach method was developed with steps, giving problems, formulating problems, hypotheses, experiments, collecting data, analyzing data, and making conclusions. The method used is the ADDIE development method, which analyzes, designs, develops, implements, and evaluates. Developing inquiry-based worksheets and testing the effectiveness of these worksheets in the learning process. The research subjects were 22 class XI students of SMA N 4 Sijunjung. The instrument used was a student worksheet and a curiosity attitude questionnaire. Assessment of the student worksheet was carried out by validation tests of media experts, material experts, and questionnaires for teachers. The validation results of media experts showed 92.30% (very good), and media experts scored 90.21% (very good), while trials on teachers and students showed scores of 86.13% and 89.16% (very good). The results of the student worksheet effectiveness test used the medium criterion N-Gain test, value 0.32. This shows that inquiry-based worksheets equipped with Phet simulations deserve to be good teaching materials and can increase students' curiosity in high school physics learning on the kinetic theory of gases.
Pengaruh Penggunaan Earphone selama Pembelajaran Daring Terhadap Resiko Kejadian Noise-Induced Hearing Loss
Authors: Diniya Diniya , Ilhami Aldeva , Permana Niki Dian , Marizal M
Published: August 2023

Sebelum penerapan pembelajaran daring pada masa pandemi covid-19, kebanyakan penggunaan earphone untuk kebutuhan mendengarkan musik dan menelepon. Penggunaan earphone menjadi meningkat sejak diberlakukannya pembelajaran daring, online meeting dan webinar. Tujuan penelitian ini adalah mengkaji lebih dalam terkait faktor yang mempengaruhi penggunaan earphone dalam pembelajaran daring terhadap risiko kejadian noise induced hearing loss. Penelitian ini menerapkan penelitian survei dalam skala kecil dengan pemilihan sampel secara sistematis. Desain klasifikasi sampel menggunakan metode decision tree. Metode pengumpulan data menggunakan internet interviews melalui instrumen kuesioner dalam bentuk google form. Analisis data berupa statistik deskriptif berbantuan aplikasi RapidMiner. Berdasarkan hasil analisis data, dapat disimpulkan bahwa selama pembelajaran daring adapun faktor yang paling mempengaruhi penggunaan earphone adalah status pekerjaan yaitu mahasiswa. Semakin lama adanya pembelajaran daring maka semakin sering mahasiswa menggunakan earphone. Sebanyak 51% responden menggunakan earphone selama pembelajaran daring namun hanya 27% yang mengetahui fungsi noise dan 11% yang mengetahui fitur akustik pada earphone.
Pengembangan Media Pembelajaran Menggunakan Lectora Inspire pada Materi Metabolisme Sel di SMA Negeri 2 Percut Sei Tuan
Authors: Dhani Fadil Rahmat , Brata Wasis Wuyung Wisnu
Published: August 2023

Penelitian ini bertujuan untuk kevalidan media pembelajaran lectora inspire, uji kelayakan pada media pembelajaran lectora inspire dengan materi metabolisme sel dilakukan oleh ahli media, ahli materi, dan ahli pembelajaran, menggunakan pretest dan posttest untuk mengetahui efektifitas media pembelajaran lectora inspire , dan respon siswa serta guru biologi. Subjek penelitian ini adalah anak kelas XII SMA Negeri 2 Percut Sei Tuan yang berjumlah 40 orang. Jenis penelitian ini menggunakan penelitian pengembangan atau Research and Development menggunakan model ADDIE. Instrumen penelitian ini yaitu lembar validasi ahli materi, validasi ahli media, validasi ahli pembelajaran, soal pretest dan posttest, respon peserta didik, dan respon guru. Berdasarkan hasil validasi dan analisis pretest dan posttest media pembelajaran lectora inspire pada materi metabolisme sel ini sangat layak digunakan sebagai media pembelajaran biologi.
Pengaruh Proporsi Volume Air Cucian Beras dalam Air Kelapa terhadap Sifat Organoleptik Nata de Coco
Authors: Zaura Asyaratil , Iswadi Iswadi , Samingan Samingan
Published: August 2023

Nataade.coco merupakan produk fermentasi,air kelapa oleh Acetobacter xylinum..Air cucian beras dapat membantu peningkatan mutu nata. Penelitian ini bertujuan untuk mengetahuiipengaruh proporsi volume air hasil cucian beras dalam air kelapa terhadap sifat organoleptik Nata de coco. Metode.eksperimental.dengan desain Rancangan Acak Lengkap (RAL) non faktorial 5 perlakuan digunakan dalam penelitian ini. Perlakuan terdiri dari P0 (1000 ml air cucian beras), P1 (1000 ml air kelapa), P2 (250 ml air cucian beras dan 750 ml air kelapa), P3 (500 ml air beras dan 500 ml air kelapa) dan P4 (750 ml air dari cucian beras dan 250 ml air kelapa) masing-masing terdiri dari 5 ulangan. Data dianalisis dengan ANAVA serta uji.lanjut dengan Uji Beda Nyata Jujur (BNJ) dan Jarak Nyata Duncan (JNTD) pada taraf kepercayaan α = 0,05. Hasil analisis terhadap empat kriteria uji organoleptik menunjukkan bahwa aroma terbaik nata terdapat pada P2, rasa terbaik terdapat pada nata P1, warna dan tekstur terbaik terdapat pada nata P3. Simpulan dalam penelitian ini adalah Nata de cocoodengan campuran air. cucian beraslpadajP3 adalah nata yang memiliki penilaian tertinggi oleh panelis karena mempunyai tekstur dan warna terbaik dibandingkan nata perlakuan lain.
Development of a Scale to Measure Children's Educational Mobile Application Usage for Foreign Language
Authors: Uygun Derya , Fırat Mehmet
Published: August 2023

The widespread use of mobile applications in education has led to the need for reliable and valid measurement tools to assess their impact on language learning, particularly among young learners. This study investigated the developmental process and psychometric properties of the Children's Educational Mobile Application Usage for Foreign Languages Scale. The item pool was created by examining the studies obtained from the literature review. To evaluate the appearance and content validity of the scale, the expert assessment of the scale, which the researcher developed, was applied to 19 experts. Consequently, the experts' opinions were considered to update the Children's Educational Mobile Application Usage for Foreign Languages Scale. Pilot studies were conducted with 37 students in the 4th grade. Data were collected from 309 4th-grade students to conduct reliability and validity studies. Confirmatory Factor Analysis was used to determine the scale's construct validity. The Chi-square/degrees of freedom ratio is 2.54, and the Comparative Fit Index value is calculated as .954. The Confirmatory Factor Analysis confirmed the theoretical structure consisting of 16 items with three factors, and the compliance indices showed perfect compliance. Cronbach Alpha (α) coefficient was used to determine the scale's reliability. The Cronbach Alpha value is calculated as 0.945. As a result, the Children's Educational Mobile Application Usage for Foreign Languages Scale was valid and reliable. The study highlights the novelty of the scale, being one of the first psychometric scales in the literature explicitly targeting children's educational mobile application usage for foreign language learning. It can aid institutions in developing or updating mobile applications and investigating the relationship between children's educational mobile application use and other variables. While this study presents a valuable contribution to the field, it also acknowledges limitations, such as the sample size and reliance on personal statements for data collection. Nonetheless, Children’s Educational Mobile Application Usage for Foreign Languages opens new avenues for research and has the potential to enhance language education by harnessing innovative technology-driven approaches.
PRÁTICA DO ALEITAMENTO MATERNO EXCLUSIVO: CONHECIMENTO DE GESTANTES
Authors: Takemoto Angélica Yukari , Soares Simone Balduino , Birolim Marcela Maria , Prado Eleandro , Rossa Roberta , Michalczyszyn Kelly Cristina , Ichisato Sueli Mutsumi Tsukuda
Published: August 2023

Introdução: o aleitamento materno exclusivo (AME) é definido quando a criança recebe apenas o leite humano direto da mama ou ordenhado, sem a oferta de qualquer líquido ou alimento, exceto medicamentos. É preconizado pela Organização Mundial de Saúde até seis meses de idade, pois é a nutrição suficiente para crescimento e desenvolvimento da criança. Entretanto, sua adesão está muito aquém do recomendado pelos órgãos nacionais e internacionais. Objetivo: identificar o conhecimento das gestantes referente à prática de aleitamento materno exclusivo. Metodologia: pesquisa qualitativa, realizada com treze gestantes, com idade gestacional acima da 25ª semana. Os dados foram coletados por meio de entrevista gravada em domicílio e submetidos à análise do Discurso do Sujeito Coletivo. Resultados: três categorias emergiram a partir da análise dos discursos: 1) Benefícios do leite materno, 2) O (des)conhecimento sobre o aleitamento materno exclusivo e 3) A prática de educação em saúde sobre o aleitamento materno. As gestantes entendem sobre os benefícios do leite materno para a saúde materno-infantil, porém, desconhecem o real conceito da prática de aleitamento materno exclusivo, uma vez que as gestantes associam a ausência do aleitamento materno exclusivo somente quando oferecem outros tipos de leites ou alimentos. Para elas, na oferta de chás e água, os bebês ainda permanecem em amamentação exclusiva. Conclusão: reforça-se a importância das orientações acerca da prática de amamentação exclusiva, reforçando sua desmistificação em relação ao uso de chás e água, bem como incluindo as desvantagens do desmame precoce. Esse conhecimento pode influenciar positivamente no bem-estar e a qualidade de vida do binômio mãe-filho.
OLHANDO O SOCIAL DO EMPREENDER: REFLEXÕES DA PEDAGOGIA EMPREENDEDORA
Authors: Bezerra Marcos Sales , Pereira Marilene Aparecida
Published: August 2023

O debate sobre o empreendedorismo no contexto brasileiro é atual, o nosso objetivo será discutir se há relação da Pedagogia Empreendedora com o Empreendedorismo Social. Argumentamos que, no Brasil o empreendedorismo se legitima pelo ideário econômico suprimindo a atuação da população negra, avançando numa breve problematização, que por vezes, não enunciam tratar da raça nos estudos do empreendedorismo. Metodologicamente, realizamos uma pesquisa qualitativa de caráter exploratória de fonte bibliográfica e documentais. Os resultados apontaram que, a raça são imperativos excludentes e identificamos também forte ligação da Pedagogia Empreendedora com os pilares apontados do Empreendedorismo social.
Pengaruh Struktur Aset dan Pertumbuhan Penjualan Terhadap Struktur Modal dengan Risiko Bisnis Sebagai Variabel Moderating
Authors: Hermayanti Rizky , Pentiana Destia , Dewi Anita Kusuma
Published: August 2023

The purpose of this study was to examine the effect of asset structure and sales growth on capital structure with business risk as a moderating variable by focusing on LQ45 indexed companies on Indonesia Stock Exchange in the period of 2015-2018. Capital structure was a dependent variable, while asset structure and sales growth were independent variables and business risk was a moderating variable. The sampling method used was purposive sampling with a sampel of 26 companies during the observation period of 4 years in a row to produce a tatal of 104 samples and 81 for samples after data transformation. The analysis technique used in this research used SPSS 22 version with multiple linier regresision analysis. The results of this study indicate that asset structure does not effect on capital structure, sales growth has an effect on capital structure, business risk can not moderated effect between asset structure with capital structure and business risk can moderated effect between sales growth with capital structure.
Penerapan Pengungkapan Sustainability Reporting Terhadap Kinerja Keuangan Perusahaan
Authors: Zakia Dewi , Puspitasari Endah Yuni , Wijaya Lihan Rini Puspo , Dzulhasni Sahilly
Published: August 2023

This study aims to examine the effect of information value in terms of financial statement disclosure as measured using the GRI index and divide it into two main categories, namely hard environmental disclosure and soft environmental disclosure and sustainability reporting on company stock prices. The research was conducted on ISRA participants in 2020-2022. The company's stock price is measured using the price model developed by Ohlson (1995). Data were analyzed using multiple linear analysis.
Efektivitas Insektisida Botani dari Daun Mimba dan Wedusan sebagai Pengendalian Kepik Penghisap Kakao
Authors: Wardati Irma , Atmaja Fama Rudi , Erawati Dyah Nuning , Galushasti Andarula
Published: August 2023

The impact of cocoa fruit-sucking ladybugs (Helopeltis antonii Signoret) is getting higher, resulting in control by considering costs and abundant raw materials. The study aimed to ascertain the efficiency of botanical insecticides made from neem and wedusan as controllers and their effect on the behavior of cacao fruit-sucking ladybugs. The research was carried out from May to August 2021 in Petungombo Hamlet, Sepawon Village, Plosoklaten District, Kediri Regency. This study used a Randomize Block Design Non-Factorial with the factors tested including I0 (no insecticide), I1 (5% neem leaf botanical insecticide), I2 (10% wedusan leaf botanical insecticide), and I3 (neem leaf vegetable botanical combination 5% and 10% wedusan leaf botanical insecticide). Further testing uses the Least Significant Difference test with a level of 5%. The results showed that the insecticidal substances of neem leaves and botanical insecticides of wedusan leaves were effective against ladybugs sucking cocoa fruit pods with a value of Lethal Time Fifty. The results were the fastest with a combination of the two over 111 hours and significantly affected behavioral changes classified as very low to low changes.
Respons Planlet Stevia (Stevia rebaudiana) terhadap Penambahan berbagai Konsentrasi Thidiazuron (TDZ) dan Naphthalene Acetic Acid (NAA) secara in Vitro
Authors: Dimas Muhammad , Indrawati Wiwik , Supriyatdi Dedi
Published: August 2023

Stevia can be developed by vegetative and generative propagation, while the generative propagation of stevia can be done through seeds. Conventional provision of seeds or seedlings has a low success rate. Propagation via tissue culture is faster, produces more seeds, and is identical to the parent, so the plants’ quality is expected. Plant growth regulator (PGR) often used for tissue culture is type auxins, cytokinins and gibberellins. The function of auxin and cytokinin for division cells, cell elongation, cell differentiation and organ formation. This research aims to get the concentration as well as the best combination for the growth of stevia plants against the administration of thidiazuron (TDZ) and naphthalene acetic acid (NAA). Research carried out by the randomised block design (RBD) factorial pattern consisting of two factors: TDZ and NAA. The first factor is TDZ concentration consisting of three levels: 0 mg.l-1 (T0), 1 mg.l-1 (T1), and 2 mg. l-1 (T2). The second factor is NAA concentration, which consists of three levels: 0 mg.l-1 (N0), 1 mg.l-1 (N1), and 2 mg.l-1 (N1). If there is a difference in data analysis using the F test, then proceed with the BNT level test of 5%. Based on the research results obtained, the influence of TDZ growth regulators and no effect of the concentration of NAA growth regulator on stevia bud multiplication book number. There is an effect of TDZ on plantlet height, leaves, and stevia shoot multiplication nodes.
Respon Pemberian Jenis Zpt Dan Lama Perendaman Yang Berbeda Terhadap Pertumbuhan Stek Batang Tanaman Anggur (Vitis vinifera L.)
Authors: Firgiyanto Refa , Arbi Juliantoro Isyrafil
Published: August 2023

Pembentukan akar (adventif) dan tunas serta masa dormansi yang lambat merupakan faktor penghambat keberhasilan pelaksanaan stek pada tanaman anggur. Meningkatkan pertumbuhan akar dan tunas yang lambat serta mempercepat masa dormansi tanaman adalah upaya untuk mengatasi hal tersebut. Tujuan penelitian ini adalah untuk mengetahui respon pertumbuhan stek batang tanaman anggur (Vitis vinifera L.) terhadap lama perendaman pada beberapa jenis ZPT. Penelitian ini dilaksanakan selama 3 bulan pada bulan Januari sampai bulan April 2021, bertempat di halaman rumah Desa Jurangsapi, Kecamatan Tapen, Kabupaten Bondowoso, Jawa Timur pada ketinggian 226 meter di atas permukaan laut. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) Faktorial dengan faktor pertama adalah jenis ZPT (Z), sebanyak 3 level, yaitu: Z1: Rootone-F 300 mg/liter air, Z2: ekstrak bawang merah 800 ml/liter air, Z3: ekstrak tauge 300 ml/liter air, dan faktor kedua adalah lama perendaman (L) sebanyak 3 level, yaitu: L1: 0,25 jam, L2: 6 jam, L3: 12 jam. Hasil penelitian menunjukkan bahwa faktor tunggal jenis ZPT berpengaruh terhadap peningkatan panjang tunas (8,10, dan 12 MST), diameter tunas (6 MST), dan jumlah daun (10 dan 12 MST) tanaman anggur dengan ZPT terbaik Rootone-F. Lama perendaman memiliki pengaruh yang nyata terhadap persentase keberhasilan tumbuh tanaman dengan perlakuan terbaik lama perendaman 6 jam. Sedangkan interaksi antar perlakuan jenis ZPT dan lama perendaman berpengaruh nyata terhadap panjang tunas (6,8,10, dan 12 MST), jumlah daun (4, 8,10, dan 12 MST), dan bobot basah tajuk stek batang anggur dengan perlakuan terbaik ZPT Rootone-F serta lama perendaman 0,25 jam.

 

Kata kunci : auksin; lama perendaman; stek batang; Vitis vinifera L. var. prabu bestari.
Sumber Kerentanan Ekonomi Petani Kopi Di Hulu DAS Lampung
Authors: Fitriani Fitriani , Kuswadi Didik
Published: August 2023

Penguatan ketangguhan rumahtangga petani menghadapi risiko ketidakberlanjutan melalui peningkatan kemampuan daya adaptasi dan mitigasi kondisi yang sulit perlu terus dilakukan.  Sumber-sumber potensi kerentanan ekonomi rumahatangga petani menjadi informasi awal untuk landasan penanggulan risiko usaha.  Kemampuan menemukenali sumber potensi kerentanan ekonomi akan menjadi stimulus upaya peningkatan produktivitas, pendapatan, dan pertumbuhan ekonomi perdesaan.  Penelitian ini fokus bertujuan untuk menggali sumber-sumber potensi kerentanan ekonomi rumahtangga petani kopi di hulu DAS Lampung. Penelitian survey dilakukan pada daerah sentra produksi kopi di tiga kecamatan yang berada dalam wilayah tangkapan air DAS Way Besai Lampung Barat, yaitu Kecamatan Air Hitam, Way Tenong, dan Sumber Jaya.  Melibatkan jumlah responden 165 petani kopi aktif.  Metode analisis data menggunakan pendekatan statistik non-parametrik dengan model multinomial regression.   Hasil penelitian menunjukkan bahwa sumber potensi kerentanan ekonomi petani di hulu DAS sangat terkait erat dengan kepemilikan dan luasan asset lahan yang dimiliki.  Asset lahan menjadi sumber utama penerimaan rumahtangga petani, alokasi tenaga kerja, dan pengeluaran rumahtangga baik pangan maupun non pangan, termasuk untuk keperluan tabungan dan investasi.  Faktor-faktor penting ini menjadi entry point dalam upaya membangun resilisensi rumahtangga petani yang tangguh.  Resiliensi  rumahtangga menjadi modal dasar dalam pencapaian produksi berkelanjutan.
Water Productivity In Drip Irrigation System For Hydroponic Caisim Plant (Brassica chinensis var. Parachinensis) With Various Polybag Sizes And Different Planting Media
Authors: Darmaputra I Gde , Idrus Muhammad , Suprapto Suprapto
Published: August 2023

his research was conducted in a plastic house at the Lampung State Polytechnic from June to October 2022. The study was a factorial experiment consisting of two factors with a randomized block design. The first factor is the type of planting media with 4 kinds, such as cocopeat, husk charcoal, sand, and soil. The second factor is the polybag size, such as small, medium, and large sizes. Each factor or treatment was repeated 3 times. The tools and materials used are drip irrigation, digital scales, polybags, pearl NPK fertilizer and caisim seeds. The objectives of the study were (1) to measure the growth and production of caisim plants on various planting media and polybag sizes, (2) to measure the amount of irrigation water used, and (3) to calculate the water productivity of caisim plants. The observed variables included crop production, amount of water use, and water productivity. Data analysis using ANOVA at the 5% significant difference test level. The results showed that there was no interaction between the type of planting media and the size of polybags, but the response in the treatment between types of planting media and between polybag sizes was significantly different. The type of media significantly affected the number of leaves, plant height, production, and water productivity of hydroponic caisim plants using a drip irrigation system. Polybag size did not significantly affect the number of leaves, plant height, production, and water productivity of hydroponic caisim plants using a drip irrigation system. In hydroponic caisim cultivation using drip irrigation, cocopeat growing media gave an average number of 9.8 leaves, plant height 34.4 cm, production 97.1 g, and water productivity 6.18 kg/m3 and was not significantly different from soil medium.
Pyoderma gangrenosum with Marfan syndrome and Crohn’s disease: A rare association
Authors: Dhanesh Dhanya , Jayapalan Sabeena , Nair Pradeep S. , Sudhesan Athira
Published: August 2023

A 22-year-old man presented with multiple, painful ulcers on the thighs, legs, and face of 10-day duration and diarrhea and bleeding per rectum of 2-year duration. The ulcers were tender and had a peripheral violaceous border. General examination revealed tall stature, long extremities, kyphosis, arachnodactyly, and hyperextensible wrist and thumbs. The arm span was more than the height and the thumb sign and wrist sign were positive, diagnostic of Marfan syndrome. Skin biopsy from the edge of the ulcer showed infiltrates of neutrophils and lymphocytes in the dermis and subcutaneous tissue. A detailed evaluation ruled out other causes for skin ulceration and we made a diagnosis of pyoderma gangrenosum. Echocardiogram demonstrated mitral valve prolapse. Computed tomography of abdomen showed segmental mucosal thickening as skip lesions in the colon and rectum. Endoscopy showed chronic colitis with multiple punched out ulcers. Colonic biopsy showed noncaseating granulomas suggestive of Crohn’s disease. Although inflammatory bowel disease is a well-known association of pyoderma gangrenosum, we did not come across any previous reports of coexistence of pyoderma gangrenosum, Crohn’s disease, and Marfan syndrome.
The effects of soy-pulp extract and low-calorie sweetener on quality characteristics and glycemic index of breakfast snack
Authors:   The Table and Food Coordinate Society of Korea, Kim Yang Suk , Kwon Jung Hyun , Lee Su Jin , Cheon Hee Soon , Kim Jin Suk , Kim Bumsik
Published: August 2023

This study developed a nutrition bar and granola, which are low in calories and inhibit the absorption of sugars, and measured changes in product characteristics such as glycemic index and consumer acceptability. This study conducted an inhibition test of carbohydrate digestive enzymes activity and a postprandial glycemic measurement test to verify the glycemic improvement effect of the soy-pulp extract. According to the results of the carbohydrate digestive enzyme inhibition test, the inhibitory activity was higher in the order of soy-pulp > momordica charantia, red bean > ecklonia cava, and black bean. DPPH and ABTS tests also confirmed the antioxidant effect of the soy-pulp extract. In the postprandial glycemic control test conducted on 18 adults aged 20-60 years, nutrition bars containing low-calorie sweeteners and soy-pulp extract showed significantly lower glycemic values at 30, 45, and 120 minutes after consumption compared to sugar-containing products. In case of granola, products containing low-calorie sweeteners and soy-pulp extract (experimental group) showed a significant decrease in glycemic values at 15 minutes after consumption compared to sugar-containing products (control group). In the sensory evaluation to measure the change in consumer preference, the experimental group showed a better preference for sweetness and savory taste than the control group (p < 0.05), and there was no significant difference in color and overall taste. Consequently, if low-glycemic sweeteners and soy-pulp extracts are used instead of sugar in the production of breakfast snacks such as nutrition bars and granola, it is possible to expect not only the effect of suppressing postprandial blood sugar rise but also the improvement of taste, such as sweetness and savory taste.
An Automated On-The-Fly Optimization of Resource Allocation for High-Throughput Protein-Ligand Binding Free Energy Simulations
Authors: Koby S. Benjamin , Gutkin Evgeny , Patel Shree , Kurnikova Maria
Published: August 2023

Molecular dynamics simulations to compute protein to small molecule binding free energies are becoming a valuable tool in the early stages of drug discovery. However, their cost and complexity are often prohibitive for high-throughput studies. Herein, we present an automated workflow for the thermodynamic integration scheme with the “on-the-fly” optimization of computational resource allocation for each λ-window of both relative and absolute binding free energy simulations. This iterative workflow utilizes automatic equilibration detection and convergence testing via the Jensen-Shannon distance to determine optimal simulation stopping points in an entirely data-driven manner. We benchmark our workflow on the well-characterized systems cyclin-dependent kinase 2 and T4 Lysozyme L99A/M102Q mutant, as well as the more flexible SARS-CoV-2 papain-like protease. We demonstrate that this proposed protocol can achieve over an 85% reduction in computational expense while maintaining similar levels of accuracy when compared to other benchmarking protocols. We examine the performance of this protocol on both small and large molecular transformations. The cost accuracy tradeoff of repeated runs is also investigated.
Electroreductive Deoxygenative C–H and C–C Bond Formation from Non-Derivatized Alcohols Fueled by Borohydride Oxidation
Authors: Villo Piret , Lill Malin , Alsaman Zainab , Soto Kronberg Adrian , Chu Victoria , Ahumada Guillermo , Agarwala Hemlata , Ahlquist Mårten , Lundberg Helena
Published: August 2023

Alcohols are one of the most common organic compound classes among natural and synthetic products. Thus, methods for direct removal of C–OH groups without the need for wasteful pre-functionalization are of great synthetic interest to unlock the full synthetic potential of the compound class. Herein, electroreductive C–OH bond activation and subsequent deoxygenative C–H and C–C bond formation of benzylic and propargylic alcohols is demonstrated. Experimental and theoretical studies indicate that the reductive C–OH bond cleavage furnishes an open shell intermediate that undergoes a radical-polar crossover to the corresponding carbanion that subsequently undergoes protonation to furnish alkane products. Furthermore, we demonstrate the carbanion can be trapped with CO2 to form arylacetic acids, representing the first example of deoxygenative electrochemical C–C bond formation from non-derivatized alcohols. The cathodic transformations are efficiently balanced by the anodic oxidation of borohydride additives, a strategy that serves as a highly attractive alternative to the use of sacrificial metal anodes.
Do Information Technology and Human Resources Create Business Performance: A Review
Authors: Sutrisno  , Ausat Abu Muna Almaududi , Permana Budi , Harahap Muhammad Ade Kurnia
Published: August 2023

Purpose: Nowadays, information technology is used massively by business organisations in order to reap maximum profits. This condition is possible if the organisation has superior human resources in the IT field. The purpose of this research is to review and convince that information technology and human resources are important factors for the success of business organisations to achieve the ideal vision and mission that has been designed before. The two factors complement each other and cannot be separated.
 
Theoretical framework: Information technology will have a significant impact on business development if operated properly by competent and capable humans. Information technology and the human element, among others, fall into the category of tangible and intangible resources. So, this study will also slightly correlate the RBV theory that has been slightly discussed in the previous paragraph. In addition, it complements the discussion of the study to make it more interesting and comprehensive.
 
Design/Methodology/Approach: The research method took place in three stages. The first step was to collect and then review available literature and research. Next, the data was examined and the findings incorporated into the study framework. Third, instrument development. This stage involves detailing all the variables and describing the measurement items that have been developed.
 
Findings: The results of this study have provided evidence that human proficiency in IT will bring blessings to profit-oriented organisations. Moreover, the current business environment is increasingly dynamic and disruptive.
 
Research, practical & social implications: This research is expected to be a useful input for business people to be more courageous in making decisions when it comes to investing in IT and human resources in order to create superior and competitive business performance.
 
Originality/Value: The results of this study are expected to be useful input for business people to be more courageous in making decisions when investing in IT resources and human resources in order to create superior and competitive business performance. In addition, it is also expected to be a formal discussion material in universities, especially business administration and management study programmes so that new and fresh ideas can be found that can be used as further research material so as to enrich the knowledge literature.
Purposive Sampling Technique and Ordinary Least Square Analysis: Investigating the Relationship Between Managerial Overconfidence, Transfer Pricing and Tax Management in Indonesian Stock Exchange-Listed Firms
Authors: Suryani Arna , Herianti Eva
Published: August 2023

Objective: This study investigates the relationship between managerial overconfidence, transfer pricing, and tax risk, with a focus on tax management's moderating role.
 
Theoretical framework: Tax management is a critical concern due to its pivotal role in financing government activities. Low tax revenues in industries like manufacturing can adversely affect these activities, highlighting the need for effective tax management strategies. Managerial overconfidence can influence these strategies, potentially leading to positive and negative impacts on tax management.
 
Method: Population of this study was manufacturing companies listed in Indonesia Stock Exchange in 2014-2019 period. The analysis made from 2015-2019, while 2014 was used as the basis to estimate the sales and asset growth as the proxy of managerial overconfidence. The sample of this study was selected using purposive sampling technique with the following criteria, manufacturing companies listed in IDX in 2014-2019 period, the company should have at least five companies in sub sector to estimate the managerial overconfidence per subsector to obtain data variation.
 
Results and conclusion: Findings indicate a significant relationship between managerial overconfidence and tax management, with managers demonstrating overconfidence tending to employ aggressive tax management strategies, thus minimizing tax payments. Furthermore, this study reveals inconsistencies in the research surrounding overconfidence's impact on tax management, necessitating further exploration.
 
Implications of the research: These results have implications for understanding the role of managerial traits in the decision-making process and developing effective tax management strategies to maximize government revenue.
 
Originality/Value: The present study confirms the agency theory's efficiency perspective, stating that overconfident managers may minimize tax management practice due to risk contingency or because they consider the long-term benefit cost. Overconfident managers are viewed as more effective in taking advantage of the growth potential, allowing them to enhance the organization's performance instead of minimizing tax payment that contains risk contingency.
Factors Affecting Demand for Accounting Services of Enterprises Using Cloud Accounting in Hanoi
Authors: Binh Nguyen Van , Bay Nghiem Van , Ha Dao Ngoc , Thuy Truong Thị
Published: August 2023

Purpose: The article analyzes the impact of factors affecting the demand for accounting services of enterprises using cloud accounting in Hanoi.
 
Theoretical framework: This paper uses model Factors Affecting Demand for Accounting Services of Enterprises Using Cloud Accounting.
 
Design/Methodology/Approach: The research method uses a questionnaire survey of accountants, chief accountants, business managers of enterprises in Hanoi. After the survey results are available, data processing is performed by statistical methods to determine the weight and frequency of the selected factors, and the data is processed on SPSS statistics 25 software to estimate the impact of the selected factors, factors affecting the demand for accounting services of enterprises using cloud accounting in Hanoi.
 
Findings: Research results show that Cost Of Using Accounting Service, Trademark, Introduction, Accounting Professional Qualification, Benefits Of Using Accounting Services, Characteristics Of Businesses Using Cloud Accounting, Supplier's Support have a positive impact on the demand for accounting services of enterprises. businesses using cloud accounting in Hanoi.
 
Research, practical   &   social   implications: Based on the research results, the author has proposed recommendations to improve the demand for accounting services of businesses using cloud accounting in Hanoi.
 
Originality/Value: This study fills the gap in the Demand for Accounting Services of Enterprises Using Cloud Accounting in Hanoi.
Antecedents of Domestic Tourist Visit Intention: An Insight From Ijen Crater Indonesia
Authors: Berutu Meta Bara , Usman Osly , Suhud Usep , Krissanya Nofriska , Sari Dewi Agustin Pratama
Published: August 2023

Purpose: This research examines the relationship between expectation, perceived value, social value, and visit intention in Indonesia's Ijen Crater, a renowned destination. Additionally, it sought to examine whether Ijen Crater's uniqueness could attract tourists’ interest in visiting the location.
 
Theoretical framework: This study uses a theoretical basis of consumer behavior to measure tourists through their values.
 
Design/Methodology/Approach: The purposive sampling method was used to select participants aged 17-35 who have never visited Ijen Crater. Out of 248 responses collected through an online survey, 240 were evaluated using the PLS-SEM analysis process. A quantitative exploratory technique was employed to investigate the intention of Indonesian tourists to visit the region.
 
Findings: The results showed that perceived values, expectations, and social values positively influence the intention to visit. However, expectations and social values did not significantly influence the intention to visit.
 
Research, practical & social implications:  Based on  the  research  findings,  our study emphasizes that  social media is able to introduce these tourist attractions more broadly to the public so that people are able to see the beauty and meaningful experiences.
 
Originality/Value: The research's originality lies in demonstrating that destinations unable to showcase their uniqueness cannot generate expectations of motivating tourists to visit. Moreover, destinations not offering core values can only provide tourists with the pleasure of attending festivals, which complement core tourism.
DO ANALÓGICO AO DIGITAL: REFLEXÕES SOBRE A RELAÇÃO DE CONSUMO NAS PLATAFORMAS DIGITAIS E AS IMPLICAÇÕES REGULATÓRIAS
Authors: Biondi Marcos Alexandre , Francisco dos Santos José Carlos
Published: August 2023

Este pensar avalia o posicionamento das cinco diferentes gerações que, pela primeira vez, desde que começaram a ser estudadas, convivem e interagem no mesmo período histórico e tecnológico. Conhecidas as bases estruturais do consumo por parte dessas gerações, percebem-se os mais velhos sempre com maiores dificuldades para aceitar inovação e tecnologia, divergindo dos mais novos. Nesse sentido, o objetivo deste estudo é focalizar o conjunto das gerações de consumidores no ambiente de consumo digital com relação às implicações das diversas formas de regulação. A pesquisa apresentada caracteriza-se como exploratória e descritiva, com emprego do método hipotético-dedutivo para guiar a análise. Resulta uma abordagem conceitual e de consequência a respeito das gerações no modo como interagem com o meio digital, principalmente em termos da relação de consumo, comumente acionada por uma simples busca na internet; seguida dos inúmeros algoritmos movimentados correlacionando hábitos com respeito a serviços ou produtos, todos requerendo informações dos respectivos consulentes. Considera-se importante chamar atenção para o fato de que as regulamentações estão sendo encaminhadas, mas ainda requerem atenção dos consumidores em relação ao seu comportamento no ambiente digital, área em que a Big Tech atua de forma vigilante para o levantamento de dados a respeito das interações verificadas do ponto de vista de consumidores e da geração da qual fazem parte.
OS PRINCÍPIOS DA VEDAÇÃO DO RETROCESSO ECOLÓGICO E DA PREVENÇÃO E PRECAUÇÃO ÀS LICENÇAS AMBIENTAIS: UMA ANÁLISE DA AÇÃO DIRETA DE INCONSTITUCIONALIDADE Nº 6.808-DF CONTRA A LEI Nº 14.195/2021
Authors: Brasil Deilton Ribeiro
Published: August 2023

O objetivo do presente estudo é analisar as modificações implementadas nos artigos 6º e 11-A da Lei nº 11.598/2007, alterados pelo artigo 2º da Medida Provisória nº 1.040/2021 convertida na Lei nº 14.195/2021 referente ao procedimento automático e simplificado de emissão de alvará de funcionamento e licenças ambientais para atividades de risco médio que foi objeto no julgamento da Ação Direta de Inconstitucionalidade nº 6.808-DF pelo Supremo Tribunal Federal. A pesquisa se justifica pela atualidade da temática e relevância acadêmica na difusão de novidades normativas, principalmente daquelas que possam afetar o meio ambiente. A hipótese de pesquisa é no sentido se a Lei nº 14.195/2021 violou o princípio da vedação do retrocesso ecológico e os princípios da prevenção e da precaução em matéria ambiental? Utilizando-se do método dedutivo e como procedimentos metodológicos as pesquisas teórico-bibliográfica, documental, consulta de livros, artigos científicos além de dispositivos constitucionais, atos normativos federais que tratam da proteção às licenças ambientais. Como resultados alcançados verificou-se que a Lei nº 14.195/2021 é inconstitucional e viola o princípio da vedação do retrocesso ecológico (dever da progressividade), da prevenção e o da precaução em matéria ambiental que devem embasar toda e qualquer atuação pública, uma vez que o direito ao meio ambiente sadio e equilibrado deve ser assegurado não só às presentes como também às futuras gerações.
O DANO SOCIOAMBIENTAL DA ESCRAVIDÃO CONTEMPORÂNEA E A IMPUTAÇÃO DE RESPONSABILIDADE CIVIL OBJETIVA DO ESTADO: Em defesa da máxima efetividade da proteção ambiental
Authors: Menezes Glenda Grando de Meira
Published: August 2023

O trabalho escravo contemporâneo representa grave mazela social que persiste no Brasil e no mundo. Essa antiga prática degradante e violadora de direitos humanos permanece arraigada na sociedade e contrasta com o alto desenvolvimento científico e tecnológico. Segundo a Organização Internacional do Trabalho, 49,6 milhões de pessoas vivem em situação de escravidão moderna no mundo. No Brasil, entre 1995 e 2023, mais de 60 mil trabalhadores foram libertados. Desde 2020, o número de casos no país quase triplicou, de acordo com o Radar SIT. A magnitude do impacto socioambiental desse ilícito denota a inefetividade das medidas estatais no sentido de defender o meio ambiente em sua ampla concepção. O propósito desta pesquisa é discorrer sobre os fundamentos jurídicos e jurisprudenciais para atribuir responsabilidade civil ao Estado de forma objetiva e de execução subsidiária pelos danos socioambientais relacionados ao trabalho escravo. Busca-se reconhecer tal responsabilidade estatal com fundamento em sua omissão no dever de fiscalizar e controlar tais práticas ilícitas, para a proteção integral do meio ambiente e a máxima efetividade da Constituição e dos tratados internacionais de direitos humanos, considerando ainda a vulnerabilidade dos trabalhadores envolvidos. Para tanto, será utilizado o método dedutivo, descritivo e qualitativo, por meio de pesquisa doutrinária, bibliográfica, da legislação e jurisprudência.
O PARADIGMA DA EDUCAÇÃO INCLUSIVA NO PLANO DOS DIREITOS HUMANOS: QUAL O SENTIDO DA EDUCAÇÃO ANTES DE ENSINAR?
Authors: Santos Adilson Souza
Published: August 2023

O artigo apresenta um estudo sobre a importância da educação inclusiva no plano dos direitos humanos. Tem-se como objetivo geral refletir sobre os principais aspectos referentes à evolução do pensamento relativo ao campo da efetividade das políticas públicas, no que se refere à educação inclusiva, como um processo do aprender a aprender. Justifica-se o estudo, eis que a doutrina que trata da educação ao longo do tempo desenvolveu variadas teorias, contudo para ensinar no Brasil, necessita-se primeiramente de uma forma jurídica que comporte a educação inclusiva, mas não é somente isso, o docente necessita aprender a aprender para depois ensinar, pois a efetividade do direito à educação inclusiva perpassa pelas implicações e explicações fornecidas pela própria educação. Quanto à metodologia, utiliza-se o método dialético; quanto à natureza, básica; quanto aos objetivos, exploratória; e, quanto aos procedimentos, bibliográfica e documental. Busca-se na discussão, a partir do seguinte problema de pesquisa: Ao levar a educação inclusiva no plano dos direitos humanos, qual o sentido da educação antes de ensinar? Tem-se como resultados que a superação dos problemas relacionados à educação inclusiva perpassa pela evolução do pensamento consciencioso por parte de todos, sociedade e estado.
O ESTUPRO BILATERAL DE VULNERÁVEL À LUZ DA PROTEÇÃO INTEGRAL E DA HERMENÊUTICA JURÍDICA
Authors: Costa Sebastião Patrício Mendes da , Campelo Olívia Brandão Melo , Alves Luana Azerêdo
Published: August 2023

O presente artigo analisou o estupro cometido contra pessoa menor de 14 (catorze) anos de idade, no contexto anterior e posterior à lei nº 12.015/09, que acrescentou o art. 217-A ao Código Penal, e à lei nº 13.718/18, que acrescentou o § 5º ao art. 217-A do Código Penal. O art. 217-A, § 5º, do Código Penal, tipifica o estupro de vulnerável e preconiza a vulnerabilidade absoluta da pessoa com idade inferior a 14 (catorze) anos. Trata-se de um artigo de revisão, que se caracteriza pela análise e discussão de informações que já estão publicadas. O seu objetivo delimitou-se a analisar a incidência do art. 217-A do Código Penal aos adolescentes menores de 14 (catorze) anos de idade, que mantêm entre si, de maneira consentida, conjunção carnal ou outro ato libidinoso, na busca de uma solução jurídica adequada. Para tanto, utilizou-se uma abordagem qualitativa, com procedimentos de análise bibliográfica e legislativa através de uma perspectiva hermenêutica do Direito. Citou-se julgado e fundamentos utilizados pelo Superior Tribunal de Justiça (STJ) na absolvição de adolescente nessa situação. Abordou-se a proteção integral, o melhor interesse, a dignidade humana, direitos fundamentais de crianças e adolescentes, teoria a respeito do conceito e técnicas de interpretação do Direito, concluindo-se pela não incidência do art. 217-A do Código Penal aos adolescentes menores de 14 (catorze) anos de idade que, consensualmente, mantêm entre si conjunção carnal ou outro ato libidinoso.
INTERAÇÕES JURÍDICAS EM UM MUNDO TRANSNACIONAL: PERSPECTIVA EXTRAJUDICIAL
Authors: Kunrath Yasmine Coelho , Bodnar Zenildo
Published: August 2023

O direito se inter-relaciona em um mundo transnacional, e as interações jurídicas já são uma realidade. Diante desta constatação, o presente artigo investiga como ocorrem as interações jurídicas em um mundo transnacional, tanto no âmbito legislativo, quanto no judiciário, e, ainda, no âmbito extrajudicial das serventias notariais e de registro. Para tanto, analisa o aspecto conceitual do processo de transnacionalização experimentado pelo mundo atualmente, como ocorrem as interações jurídicas entre diferentes ordens jurídicas de diferentes Estados para, ao final, apresentar como tal ocorre do ponto de vista das atividades extrajudiciais de notários e registradores.Utiliza o método indutivo e os procedimentos cartesianos e conclui que as interações jurídicas extrajudiciais já são bastante comuns, e que as atividades notariais e registrais facilitam o processo de transnacionalização em certa medida. Ao final, propõe medidas que podem proporcionar uma maior efetividade para as interações jurídicas para a atividade extrajudicial em si e para a sociedade em geral.
IMPLEMENTAÇÃO DO PROCESSO JUDICIAL ELETRÔNICO PELO CONSELHO NACIONAL DE JUSTIÇA: OS DESAFIOS DO ACESSO À JUSTIÇA NO CONTEXTO DA SUSTENTABILIDADE
Authors: Gontijo Andre Pires , Silva Leonardo Peter da
Published: August 2023

Artigo sobre os desafios do acesso à justiça no contexto da sustentabilidade a partir da implementação do Processo Judicial eletrônico (PJe) pelo Conselho Nacional de Justiça (CNJ). Mediante revisão bibliográfica, como objetivos buscou-se examinar as transformações e os impactos trazidos pela implantação do PJe pelo CNJ, as atuais condições de exercício da função pública pelos atores do sistema de justiça; em seguida, pela exame doutrinário e legislativo, pretende-se verificar os desafios do PJe relacionados à efetivação do acesso à justiça como um direito fundamental, verificando as possibilidades trazidas por esse novo modelo procedimental relacionadas à sustentabilidade, com foco na Agenda 2030 da ONU. Como hipótese, constata-se que o PJe é uma realidade no Poder Judiciário, obrigando os atores do sistema de justiça a se adaptarem, rumo a um novo modelo de pensar a realidade material e processual onde se concretiza o Direito. Como resultado, verificou-se que o acesso efetivo à justiça - via PJe - deve ser encarado com racionalidade, reconhecendo as insuficiências dos serviços judiciais, quebrando paradigmas obsoletos na busca da efetividade da prestação jurisdicional. É um problema de todo o sistema de justiça e que deve ser encarado por cada uma de suas partes. Mesmo com os desafios, o PJe apresenta-se como um dos instrumentos de ampliação do acesso sustentável à justiça, tornando mais eficiente e ágil a tramitação de processos judiciais, reduzindo o uso de papel, o deslocamento de pessoas e documentos, aumentando a transparência de dados e a acessibilidade do cidadão ao sistema de justiça.