bluuebunny/crossref_metadata_2025 huggingface dataset:
La encuesta online en la investigación social y de género en tiempos de pandemia por covid-19
Authors: Ayala Carrillo María del Rosario , Zapata Martelo Emma , Pérez-Fra María Do Mar
Published: March 2023

La pandemia por covid-19 ha tenido efectos en todas las esferas de la vida. En el ámbito académico sus efectos se han visto tanto en la docencia como en la investigación. En esta última, las formas de hacer trabajo de campo y de implementar la metodología en las ciencias sociales también se ha tenido que adaptar. El uso de la tecnología ha sido indispensable, ya que muchas de las actividades se tuvieron que realizar por medios digitales. Las computadoras, y los teléfonos móviles se convirtieron en indispensables, aplicaciones como whatsapp, Google Forms, Skype, Zoom, Teams, entre otras, fueron eficaces para continuar con algunas de las actividades cotidianas, mantener contactos sociales, impartir clases, mantener y continuar con investigaciones. El presente documento tiene como objetivo sistematizar algunas de las experiencias sobre la utilización de la encuesta online autoaplicable (Google Forms) en una investigación doctoral de corte cualitativo, con el fin de reflexionar sobre la utilización de este método digital como herramienta metodológicamente válida.
El odio a la mujer, ¿efecto del mal-decirla?
Authors: Gerber Daniel
Published: March 2023

Este ensayo aborda la cuestión de la mujer y sus oposiciones a la lógica fálica, su énfasis en la singularidad. No hay denominador común para la diversidad de las mujeres existentes: esto es lo característico de lo femenino. Lacan habla de las mujeres como seres cuyo goce las hace eminentemente singulares, ahí donde los hombres estarían más inclinados a la particularidad, a ser partes que deben ensamblarse perfectamente en el todo. Las mujeres pueden vivenciarse como “Otras que ellas mismas”, es decir, no coincidir completamente con lo que ellas son. En este sentido, la práctica del análisis “feminiza” a quien se involucra en él. En la relación que los hombres mantienen con las mujeres tendrán que soportar el encuentro del Otro goce, el goce femenino,que es no todo, que hace objeción al para todos. El psicoanálisis abre la posibilidad de bien-decir la mujer, diciéndola a medias, para dejar de odiarla, de mal-decirla, por no poder decirla toda.
Presentación del dossier La industria del vestido: ¿dos experiencias que convergen?
Authors: Véras de Oliveira Roberto , Maza Díaz Cortés Octavio Martín , Rangel Martins Felipe
Published: March 2023

Presentación del dossier La industria del vestido: ¿dos experiencias que convergen?
Robust Topology Optimization of Continuum Structures under the Hybrid Uncertainties: A Comparative Study
Authors: Latifi Rostami Seyyed Ali , Li Muxi , Kolahdooz Amin , Chung Hayoung , Zhang Jian
Published: March 2023

Due to the inevitable involvement of multisource uncertainties related to the load, material property and geometry in practical engineering designs, robust topology optimization (RTO) has recently attracted increasing attention to account for these uncertain effects. However, the majority of the existing RTO works are concerned with single source uncertainty, and very few studies have considered the multisource (hybrid) uncertainties simultaneously. To this end, a comparative study on the hybrid uncertainties (HU), i.e., material-loading, geometric-loading, material-geometric, and material-geometric-loading uncertainties, for RTO of continuum structures is presented in this paper. A truncated Karhunen-Loeve expansion is adopted for uncertainty representation and a sparse grid collocation method for uncertainty propagation of the objective function and constraints. Effects of the various HU on the compliance and robust design are comprehensively investigated and compared with the RTO models under individual component uncertainty using two continuum benchmarks. An important observation from the results is that the hybrid uncertainty model is a conservative state, and the resulting RTO designs tend towards those with loading uncertainty only.
Stress resistance as a feature of character of the Ukrainians
Authors: Dudnyk Yurii
Published: March 2023

The article discloses the peculiarities of stress resistance of the Ukrainian ethnicity. Has been analyzed the importance of the national character of Ukrainians as an important determinant of stress resistance. Also, the main features of the Ukrainian national character, which are related to stress resistance have been highlighted. The significance of the collective traumatic experience as a factor in increasing vulnerability to stress has been considered. The author includes sensitivity, cordocentrism, individualism, freedom-loving, intolerance to coercion and violence, hard work, antaeuism, and optimism to the features of the national character that are associated with stress resistance. Emphasis is placed on the positive or ambiguous relationship of selected features with stress resistance. A positive or ambiguous relationship of the selected features with stress resistance was noted. The propensity of Ukrainians to provide social support in crisis situations has been disclosed, which has a significant positive effect on the psychological well-being of large groups. In the opinion of the author, taking into account the previous and past historical experience of the Ukrainian ethnicity, collective trauma appears to be a growing problem, which has a long-term negative impact on psychological well-being and stress resistance
Hrvatsko sjeme u međunarodnom prometu
Authors: Jukić Goran
Published: March 2023

Organizacija za ekonomsku suradnju i razvoj (OECD Seed Schemes) međunarodna je organizacija sa sjedištem u Parizu koja regulira promet sjemena na međunarodnom tržištu. OECD Poljoprivredni kodovi i sheme otvoreni su za sve članice ali i za ostale države koje nisu članice OECD-a odnosno za države koje su članice Ujedinjenih naroda ili Svjetske trgovinske organizacije. Republika Hrvatska prepoznala je prednosti članstva stoga je domaći sektor sjemenarstva uspio plasirati sjeme koje je poznato po visokoj kakvoći na zahtjevna međunarodna tržišta. Članstvom u OECD Seed Schemes Centar za sjemenarstvo i rasadničarstvo Hrvatske agencije za poljoprivredu i hranu od 1998. godine preuzeo je brigu oko nadzora sjemenske proizvodnje, pred i post kontrole i izdavanja certifikata za sjeme. Ova važna organizacija propisala je službene procedure, metode i tehnike tijekom umnažanja sjemena kako bi se održao identitet i genetska čistoća genotipova. OECD certifikat jamči kupcu određenu kvalitetu sjemena, a Republika Hrvatska je ovim sustavom certificiranja ostvarila suficit u korist izvoza sjemena.
Utjecaj genotipa pilića i vrste mišićnog tkiva na sadržaj karnozina i anserina
Authors: Kralik Zlata , Košević Manuela , Radišić Žarko , Gvozdanović Kristina , Galović Olivera , Kralik Gordana
Published: March 2023

Karnozin (β-alanil-L-histidin) i anserin (β-alanil-1-metil-L-histidin) su dipeptidi koji imaju značajnu ulogu u fiziološkim funkcijama kod ljudi. Prisutni su u skeletnim mišićima i moždanom tkivu mnogih kralježnjaka. Dizajniranjem krmnih smjesa s povećanim sadržajem aminokiselina L-histidina i β-alanina njihova se koncentracija u mesu tovnih pilića može povećati. Cilj ovog rada bio je ispitati utjecaj genotipa brojlera i vrste mišićnog tkiva na boju mesa i sadržaj karnozina i anserina. Istraživanje je obavljeno na pilićima genotipova Cobb 500 i Ross 308. Ukupno je utovljeno 400 pilića, podijeljenih u dvije pokusne skupine (200 komada Cobb 500 i 200 komada Ross 308). Tov je trajao 42 dana. U tovu su korištene tri komercijalne krmne smjese, starter (21,02 % proteina, do 21. dana), grover (19 % proteina, od 22.-35. dana) i finišer (18,05 % proteina od 36. do 42. dana tova). Nakon klanja i obrade trupova izmjerena je boja mesa prsa i zabataka (CIE L *, CIE a *, CIE b *). Rezultati istraživanja pokazali su da vrsta mišićnog tkiva ima statistički značajan utjecaj na boju mesa (P<0,05), dok genotip ima utjecaja samo na CIE b* vrijednost (P<0,001). Rezultati analize sadržaja karnozina i anserina u uzorcima mesa prsa i zabataka pokazuju da genotip nema utjecaj na sadržaj navedenih dipeptida u mesu (P>0,05), dok vrsta mišićnog tkiva ima značajan utjecaj (P<0,001) na njihovo deponiranje. Ustanovljen je značajno veći sadržaj karnozina (P<0,05) i anserina (P<0,001) u mesu prsa u odnosu na meso zabataka kod oba genotipa pilića.
Žižula-tradicijska kultura u oblikovanju vrtova i voćnjaka na području grada Skradina
Authors: Dorbić Boris , Matić Josip , Španjol Željko
Published: March 2023

Žižula (Ziziphus jujuba Mill.) je mediteranska voćna vrsta koja svojim ukrasnim i oblikovnim karakteristikama upotpunjuje pejsažnu sliku urbanog prostora grada Skradina. Na području Skradina ova kultura je posađena u sklopu kućnih vrtova i samostalnih voćnjaka. Danas na području grada Skradina kuća s vrtom sve više poprima gradska obilježja i udaljava se od tradicionalnog seoskog vrta. Tradicija uzgoja žižule je prvenstveno u gospodarske svrhe (radi ploda), premda je poznato da se zbog izuzetne ljekovitosti od žižule mogu još koristiti listovi i kora. Cilj rada bila je valorizacija utilitarnih i ukrasnih vrtova te voćnjaka (sveukupno 36) na području grada Skradina u kojima je posađena žižula. Kroz anketno istraživanje u uzorku od 50 ispitanika s područja grada Skradina istražili su se stavovi i percepcije o ukrasnim karakteristikama, primjeni, održavanju i ulozi žižule u gospodarstvu Skradina. Terenskim istraživanjima je utvrđeno da su za krajobrazno uređenje i oblikovanje vrtova s žižulom najveće ocijene postigli ukrasni vrtovi u sklopu stambenog objekta. U pogledu zastupljenosti (pojavnosti) u vrtovima na ovom području prevladavaju utilitarne vrste. Najveći broj stabala žižule zabilježen je u voćnjacima bez stambenog objekta. Izvrsne ocijene su dodijeljene stablima žižule u okviru voćnjaka u sklopu stambenog objekta i utilitarnim vrtovima u sklopu stambenog objekta. Rezultati anketnog istraživanja pokazuju da je vegetativnim organima ove voćke u pogledu uresnosti dodijeljena ocjena izvrstan kao i njenoj ulozi u krajobraznoj slikovitosti. Ocjenjivači atraktivnijim smatraju primjenu žižule u vrtovima nego na javnim krajobraznim površinama i parkovima. Smatraju da ova kultura treba postati i skradinski brend.
Comparison Study between Using Disposable and Non-Disposable Ventilator Circuits on Ventilator-Associated Pneumonia and Health Care Costs at a Respiratory Care Unit, Siriraj Hospital
Authors: Songmuang Jarunee , Akatat Pachcharat , Wattanagulanurak Sasithorn , Rittayamai Nuttapol , Sripalakit Siriporn
Published: March 2023

Objective: This research aimed to compare the incidence of ventilator-associated pneumonia (VAP) and ventilator circuit costs among patients using disposable ventilator circuits and patients using non-disposable ventilator circuits.

Materials and Methods: Observational research was performed consisting of the following: A retrospective chart review of a group of patients who used non-disposable circuits (n=193) and a prospective cohort study of a group of patients using disposable circuits (n=166). The sample was purposively selected based on the following inclusion criteria: patients aged 18 years old and over who were admitted to the Respiratory Care Unit, Siriraj Hospital and ventilated >48 h.

Results: VAP incidence in the group non-disposable circuits was 10.41/1,000 ventilator days (n=27, 13.8%) and 10.82 /1,000 ventilator days (n=24, 14.4%) in the group disposable circuits (p=0.871). According to the data analysis using the U-control chart, no statistically significant differences were found. The unit cost of the non-disposable circuit was lower than that of the disposable circuit (THB 295.94), while the work unit personnel satisfaction toward working with disposable circuits was at a good level (Mean=3.83) and medium level (Mean=3.12) in non-disposable circuits (p=0.002).

Conclusion: The type of ventilator circuits had no effects on VAP rate. The unit cost of non-disposable circuits was lower than that of disposable circuits, while the work unit personnel had a higher satisfaction working with disposable circuits than non-disposable circuits.
Students' perceptions of the use of technological tools that facilitate self-regulated English language learning
Authors: Iza Pazmiño Sarah Jacqueline , Chicaiza Redin Verónica Elizabeth , Encalada Trujillo Edgar Guadia , Jordan Buenaño Cristina del Rocío
Published: March 2023

This study aims to identify to what extent the use of technological tools facilitates self-regulated learning among pre-service students studying English. The methodology employed for this study was a survey design and a questionnaire was administered to 497 students studying at Zone 3. The results show that the most used strategies to self-regulate students' English language learning are related to the search of information, review and memorization, revision or review of notes and/or books, and self-assessment activities. Regarding the frequency of use of digital tools to self-regulate English language learning, 45% of the participants mentioned that they always use these tools. Furthermore, 63% of students considered that the use of technological tools facilitates self-regulated English language learning. It can be concluded that the importance of technological tools and their application in the academic context facilitates students' learning. It is also recommended to do more research in the area to explore the strengths that ICT tools must develop self-regulated learning.
La formación del docente en relación a la diversidad y educación inclusiva
Authors: Gaibor Sangache Mirella Margarita , Machay Negrete Diana Alexandra , Morales Jaramillo María Belén , Andrade Albán Jorge Rodrigo
Published: March 2023

Introducción. Este artículo tiene como finalidad comprender el desafío de la educación actual centrada hacia la concepción de la diversidad e inclusión conforme a los ejes de justicia e inclusión establecida por la sociedad. Un sistema educativo el cual promueva la atención sin discriminación y priorizando el respeto a sus derechos. Tomando como punto de partida al enfoque de la formación docente, como instauradores principales de inclusión dentro del aula y el centro formativo, aplicando un trabajo dirigido a la atención de las diversidades. Objetivo. Con el fin de conocer diferentes perspectivas de los docentes hacia la diversidad y educación inclusiva, además, identificar el nivel de formación y conocimientos que adquieren en el transcurso profesional. Metodología. La obtención de datos se realizó a través del cuestionario formación docente en inclusión de profesionales de la educación -CEFI-R. Se tomó una muestra de 65 docentes de la Universidad Técnica de Ambato. Resultados. Los resultados en las 4 dimensiones planteadas, dimensión de concepción de diversidad el 69% muestran actitudes positivas hacia la diversidad, dimensión metodológica determina que el 72% maneja una metodología adecuada, dimensión de apoyo evidencian que el 69% de los docentes proporcionan apoyos a sus alumnos y dimensión de participación de la comunidad el 86% establece el trabajo colaborativo entre el centro escolar, sus agentes, familia y la sociedad. Conclusión. Se ha concluido que la formación docente dentro de la Universidad Técnica de Ambato está encaminada al desarrollo de una educación que valore, respete las diferencias y enriquezca el proceso de enseñanza-aprendizaje. Sin embargo, promover el ejercicio de la educación inclusiva a nivel general es complejo puesto que el cantón Ambato se encuentra en proceso. Pocas han sido las instituciones interesadas en establecer escuelas inclusivas.
Estrategias socio afectivas como método de enseñanza en tiempos de pandemia Covid-19, una forma para desarrollar destrezas productivas en el aprendizaje colaborativo
Authors: Carvajal Gavilanes Andrea Karina , Pila López Rubela Jeaneth , Andrade Naranjo Diego Santiago , Arellano Reyes Milton Andrés
Published: March 2023

Introducción. Con el fin de establecer vínculos entre las estrategias socio-afectivas y el desarrollo de habilidades productivas en el aprendizaje colaborativo en tiempos de pandemia (covid-19), se toma como referencia el conjunto de estrategias que determinan las pautas generales a seguir para comunicarse de manera efectiva oralmente o por escrito, por lo que una sobrecarga de actividades individuales como única estrategia de comunicación conduce a tener un entorno socio-afectivo inadecuado para el desarrollo de la comunicación en la interactividad de clase más aún hoy en día por el encierro realizado por la pandemia (covid-19) que de una forma u otra ha limitado el uso de nuevas estrategias en el aprendizaje colaborativo. Objetivo. Determinar la incidencia que tiene las estrategias socioafectivas en el desarrollo de las destrezas productivas en el aprendizaje colaborativo en los estudiantes. Metodología.  En este contexto, se propuso realizar la presente investigación con un enfoque cualitativo-cuantitativo, en el que la población y muestra estuvo conformada por 169 estudiantes y 4 profesores. La validez de la propuesta se demostró a través de técnicas e instrumentos de investigación como las encuestas. Resultados. Durante el procesamiento de la información se presentaron los resultados mediante tablas de frecuencia y porcentajes, los análisis e interpretaciones seleccionadas. Conclusión. Las estrategias socio afectivas influyen de manera permanente y positiva en el proceso de aprendizaje colaborativo en el desarrollo de habilidades productivas en tiempos de pandemia (COVID-19).
Aportes desde la neurociencia, una perspectiva transformada para el aula
Authors: Freire Palacios Verónica Adriana , Sánchez Guerrero Mentor Javier , Castro Dávila Willyams Rodrigo , Armijos Carrión Jorge Luis
Published: March 2023

Introducción: En la actualidad, el campo de las Neurociencias ha generado importantes avances enfatizando el estudio de los procesos cognitivos, dando lugar así al nacimiento de disciplinas en diversas ramas del conocimiento científico. Entre estas disciplinas destacan la neuroeducación y la neurodidáctica, cuyos aportes son de suma importancia para los docentes que buscan basar su práctica pedagógica en el funcionamiento y respuesta del cerebro en el aula. Objetivo: El objetivo de este artículo es realizar una amplia revisión bibliográfica de los últimos 5 años, en artículos de impacto de diferentes autores, para analizar las particularidades de las definiciones a partir del significado de la neurociencia y su relación con otras ciencias. Metodología: Se utilizaron métodos de investigación teóricos y empíricos, como analítico-sintético en la sistematización de la revisión exhaustiva de los principales fundamentos que sustentan este trabajo. Resultados: Se muestra un resumen de los diferentes artículos revisados, indicando a qué revista corresponden, señalando sus autores y el año de publicación. Conclusiones: Finalmente, se concluye sobre la importancia de estos aportes y cómo orientan el rol docente y las prácticas educativas para posibilitar el logro de aprendizajes significativos en el aula, por supuesto incluyendo los conceptos, preceptos y teoría revisados en este trabajo.
Seguridad contra ataques DDoS en los entornos SDN con Inteligencia Artificial
Authors: Mejía Viteri José Teodoro , Gonzales Valero María Isabel , Fernández Torres Ana del Rocío , Crespo Torres Narcisa María
Published: March 2023

Las redes definidas por software (SDN), representan la innovación, porque combinan la administración central y la capacidad de programar la red, SDN centraliza la gestión a través de un controlador , separa el plano de control y el datos, pero al tener un único punto de control la hace vulnerable especialmente a los ataques de Denegación de Servicio Distribuido(DDoS), en la actualidad existe muchas investigaciones orientadas a mitigar este tipo de ataques a través de técnicas donde interviene la inteligencia artificial y sus diversas áreas. Este estudio describe las SDN, la inteligencia artificial, los ataques DDoS y realiza una revisión de la intervención de la inteligencia artificial para mitigar este tipo de ataques.
Insights and Field-level experiences of Non-Performing Loans in Bangladesh: The Case of State-Owned Commercial Banks (SOCBs)
Authors: Hasan Md Nazmul , Khan Sadia Noor
Published: March 2023

The banking industry of Bangladesh has been facing the most turbulent times of its history due to myriad forms of challenges. The crippling scenario has been contributed by multifarious reasons among others, corrupt loan practices and connected-party lending (i.e., lending to board members’ firm), lack of monitoring, supervision and inefficiencies of board members especially in state-owned commercial banks, monopolization of banks by certain industrialist groups, unprecedented political interferences and non-existent punitive measures for miscreants by the highest regulatory body i.e., Bangladesh Bank. All these reasons coupled with recent implication of single-digit interest rate are putting the banking industry into vulnerable state and thereby losing the trust and confidence of the mass-people. The excessive volume of NPL will possibly jeopardize the profitability of banks and erode the accumulated capital which might lead to the systematic risks of bank failures in the days to come. To this backdrop, the authors intend to shed some lights with a deeper look on the origin and effects of NPL based on a sample of 200-survey respondents and endeavored to explore industry-insights which might be of special interests to bank owners, managements bodies, regulator i.e., Bangladesh Bank (BB) and finally the shareholders.
Journal of Business Studies, Vol. XLII, No. 1, April 2021 Page 151-174
PENGARUH VARIASI ARUS LISTRIK TERHADAP NILAI KEKERASAN HASIL LASAN BAJA ASTM A36
Authors: M. Harun Humaidi  , Ahmad Fauzan Suryono  , Hendri Hestiawan
Published: March 2023

Metal inert gas (MIG) welding is widely used whenever high and medium speed melting or joining of metals is required, MIG welding uses a DC current which is ignited between the worked part and the electrode wire, where this electrode functions simultaneously as a power carrier and source. metal filler, for MIG welding the gas is inert argon gas or a mixture of argon helium. In this study, the variables to be compared are the effect of variations in electric current and hardness values ​​on MIG welding using CO2 gas. The purpose of this study was to analyze the effect of variations in electric current on the welding results, and to analyze the mechanical properties of the welding hardness value. The material used in this study as the workpiece is ASTM A36 steel with 6 pieces of length, width, and thickness dimensions of each 147 mm x 50 mm x 5 mm. The welding process is carried out by placing two workpieces parallel to the seam facing each other and a distance of 1 mm, with a current of 60 A, 100 A, and 150 A before full welding is carried out welding at the end of the workpiece so that there is no shift, then welding is carried out. full. The data collection method was carried out using the Hardness Tester hardness tester with the Brinell method at 5 test points in the weld area, the HAZ area, and the base metal area. The results showed that the welding results at a current of 60 A obtained uneven wavy, there were ridges at a current of 100 A the welding results were not too wavy, the ridges produced were slightly at a current of 150 A, the welding results were not neat in the middle of the weld area and there are pores. From the visual results of welding, the best welding results are at 100 A, the electric current used in Metal Inert Gas welding affects the weld results, the use of electric current that is close to the ASTM A36 steel welding standard (110 A – 130 A) will get better results. The best hardness value of this welding is at a current of 100 A, with almost the same average values, namely 96.52 HRB, 95.92 HRB, and 96.44 HRB.
ANALISA KOROSI PADA TANGKI REAKTOR TRIGA 2000 MENGGUNAKAN METODE INSPEKSI ULTRASONIK DAN INSPEKSI VISUAL (UNDERWATER CAMERA)
Authors: Shafira  , Hendri Hestiawan  , Bismantolo Putra
Published: March 2023

A reactor is a process device where a reaction takes place, be it a chemical or nuclear reaction and not physically. Nuclear reactors are used for various purposes, namely to create, regulate, and maintain a nuclear chain reaction at a constant rate. One method of monitoring corrosion is using an ultrasonic device to measure the thickness of the tank wall and an underwater camera tool to visually see the damage that has occurred and will provide a quantitative estimate of the corrosion rate that occurs in the system by comparing the initial weight and weight after a certain time. The corrosion rate value on the TRIGA 2000 reactor wall is obtained through the weight reduction method, and has an average corrosion value of 0.10 mmpy, while the type of corrosion that occurs on the TRIGA 2000 reactor wall is the type of intergranular corrosion. protective coating by coating organic compounds (lubricant) and controlling humidity and temperature.
MAINTENANCE DAN INSPECTION PADA RUNNER TURBIN
Authors: AM Saifutaqi Fatwa Mayfi  , Nurul Iman Supardi  , Angky Puspawan
Published: March 2023

The PLTA TES is a generator that relies on water as the driving force for a turbine unit system. There are 7 PLTA Tes turbine units that are still operating with alternating working hours. In keeping a turbine unit operating properly, one way is to do maintenance and general inspection (GI). Maintenance is one way to keep a tool or object from being damaged. Then General Inspection (GI) is a process of activities in the PLTA Test company in checking, measuring, adjusting, repairing and testing one turbine unit in operating for 20,000 hours on a regular basis so that the unit can operate better than before, maintenance is carried out. One of the turbine components that is the object of maintenance is the runner. The runner is the heart of a turbine so that it can operate by relying on flowing water so that the runner can rotate. Runners are given a spot check to see if there is a crack in the runner's condition and measure the runner's clearance so that there is no excessive friction when the runner is operating and the runner is not thirsty.
SIMULASI ANALISIS VELOCITY ALIRAN FLUIDA PADA TANGKI REAKTOR NUKLIR MENGGUNAKAN METODE COMPUTATIONAL FLUID DYNAMICS (CFD)
Authors: Mifta Aroyyani  , Agus Nuramal  , Hendri Hestiawan
Published: March 2023

Center for Applied Nuclear Science and Technology (Pusat Sains dan Teknologi Nuklir Terapan /PSTNT) is a work unit that is under and directly responsible to the Deputy for Nuclear Science and Applications of Nuclear Technology, National Nuclear Energy Agency. In PSTNT Bandung, the function of the tank is as a container to place the reactor components, the reactor shield for the heat exchanger and as a place for nuclear reactions to take place. In nuclear reactor tank flow distribution ocures in various velocity.The purpose of this practical work is to analyze the velocity of fluid flow in the reactor tank from the inlet flow to the bottom surface of the reactor and from the bottom surface to the top surface of the TRIGA 2000 reactor. The method used in this practical work is the Computational Fluid Dynamics (CFD) Velocity method. CFD is a method for simulating fluid flow. The method is processed numerically and then digitally modeled. In practice, the authors modeled and studied the conceptual design of the reactor system using CFD based on Gambit and Fluent applications in a reactor tank. GAMBIT is an application produced by fluent inc. which is useful for making a model and discrete (meshing) to be analyzed by numerical methods. Fluent is an application that can solve fluid flow cases with the results obtained after discretizing the GAMBIT application. The results by CFD shows the distribution of fluid flow from the inlet pipe to the bottom surface of the reactor tank then the flow rises to the top surface to the outlet pipe. The velocity of the fluid flow from the inlet flow to the bottom surface was getting smaller, and the smallest value was at the bottom of the nuclear reactor, by 0.164 m/s and the flow distribution from the bottom surface to the top surface of the velocity value in a nuclear reactor would be bigger by the largest value being on the top surface of the nuclear reactor is 2.9 m/s.
Morbidity and Mortality Trends in Preterm Infants of <32 Weeks Gestational Age with Severe Intraventricular Hemorrhage : A 14-Year Single-Center Retrospective Study
Authors: Choi Eui Kyung , Kim Hyo-jeong , Je Bo-Kyung , Choi Byung Min , Kim Sang-Dae
Published: March 2023

Objective : Owing to advances in critical care treatment, the overall survival rate of preterm infants born at a gestational age (GA) <32 weeks has consistently improved. However, the incidence of severe intraventricular hemorrhage (IVH) has persisted, and there are few reports on in-hospital morbidity and mortality. Therefore, the aim of the present study was to investigate trends surrounding in-hospital morbidity and mortality of preterm infants with severe IVH over a 14-year period.Methods : This single-center retrospective study included 620 infants born at a GA <32 weeks, admitted between January 2007 and December 2020. After applying exclusion criteria, 596 patients were included in this study. Infants were grouped based on the most severe IVH grade documented on brain ultrasonography during their admission, with grades 3 and 4 defined as severe. We compared in-hospital mortality and clinical outcomes of preterm infants with severe IVH for two time periods : 2007–2013 (phase I) and 2014–2020 (phase II). Baseline characteristics of infants who died and survived during hospitalization were analyzed.Results : A total of 54 infants (9.0%) were diagnosed with severe IVH over a 14-year period; overall in-hospital mortality rate was 29.6%. Late in-hospital mortality rate (>7 days after birth) for infants with severe IVH significantly improved over time, decreasing from 39.1% in phase I to 14.3% in phase II (p=0.043). A history of hypotension treated with vasoactive medication within 1 week after birth (adjusted odds ratio, 7.39; p=0.025) was found to be an independent risk factor for mortality. When comparing major morbidities of surviving infants, those in phase II were significantly more likely to have undergone surgery for necrotizing enterocolitis (NEC) (29.2% vs. 0.0%; p=0.027). Additionally, rates of late-onset sepsis (45.8% vs. 14.3%; p=0.049) and central nervous system infection (25.0% vs. 0.0%; p=0.049) were significantly higher in phase II survivors than in phase I survivors.Conclusion : In-hospital mortality in preterm infants with severe IVH decreased over the last decade, whereas major neonatal morbidities increased, particularly surgical NEC and sepsis. This study suggests the importance of multidisciplinary specialized medical and surgical neonatal intensive care in preterm infants with severe IVH.
The Influence of Social Class on Risk Behaviors Among College Students: The Mediating Role of Family Violence
Authors: Lu Yuechen , Ma Baoping
Published: March 2023

In recent years, various kinds of risk behaviors among urban and rural adolescents have increasingly aroused public concern. To explore the influence mechanism of social class and family violence on risk behaviors and the mediating effect in this process, this study selected 216 students from universities in Beijing and Hebei for a questionnaire survey based on the principle of convenient sampling. The results of regression analyses and mediating effect analysis revealed that participants' subjective social class significantly predicted risk behaviors and family violence. Correlations between variables were verified, and family violence played a partial mediating role between social class and risk behaviors. Our findings echoed previous studies on the relationships between social class, risk behaviors, and family violence in pairs. Furthermore, this study innovatively proposed and constructed a mediating model of the relationship among the three variables through statistical analysis, which offered evidence support for subsequent researches in the field of educational psychology and also provided space for further studies related to family factors.
GAS turbine sensor fault diagnostic system in a real-time executable digital-twin
Authors: Cruz-Manzo Samuel , Panov Vili , Bingham Chris
Published: March 2023

In this study, a sensor fault diagnostic system to detect/isolate and accommodate faults in sensors from an industrial gas turbine has been developed. The sensor fault diagnostic module is integrated with a gas turbine real-time executable digital-twin (RT xDT) reported in a previous study. The sensor fault diagnostic module of the digital-twin considers analytical sensor redundancy using a reference engine model to provide redundant estimates of measured engine variables. A Software-in-the-Loop (S-i-L) architecture and Hardware-in-the-Loop (H-i-L) facility are constructed to assess the sensor diagnostic module (fault detection/ fault isolation) during failure in sensors from the engine. The results demonstrated that if the discrepancy between virtual measurement (provided by digital-twin) and sensor measurement exceeds the prescribed tolerance levels, the sensor fault diagnostic logic determines the state of switching between the virtual and engine sensor measurements in a dual lane control configuration of the gas turbine control system. The sensor fault detection system implemented in the gas turbine RT xDT can be deployed onto a distributed control system of industrial gas turbines to diagnose sensor deficiencies and ensure continuous and safe operation of the gas turbine. Consequently, the developed system will increase engine availability and reliability by diagnosing engine operational deficiencies before severe failure.
OBEYING TO KYAI FOR MARRIAGE: A TRADITION IN MAQĀSID SHARĪ’AH PERSPECTIVE
Authors: Masruh Ahmad
Published: March 2023

This article is the result of a qualitative field research. The research location is at the At-Tahdzib Islamic Boarding School Rejoagung Ngoro Jombang. The direction of the discussion in this article is how to place the marriage tradition following the Kyai within the framework of maqasid marriage and maqasid shariah. The researcher uses maqasid al-nikah and maqasid shariah theory in explaining the position of the marriage tradition following the Kyai, because the maqasid al-nikah and maqasid shariah theories. The researcher argues that the marriage tradition following the Kyai provides advocacy for the protection of the bride and groom in achieving the goals of marriage and the goals of the Shari'a that arise from marriage

Keywords: marriage is obedient to the kyai, maqasid shariah.

 

 

Abstrak

Artikel ini adalah hasil penelitian kualitatif lapangan. Lokasi penelitian berada di  Pesantren At-Tahdzib Rejoagung Ngoro Jombang. Arah diskusi artikel ini adalah bagaimana mendudukkan tradisi pernikahan mengikuti Kyai dalam bingkai maqasid pernikahan dan maqasid shariah. Peneliti menggunakan maqasid al-nikah dan teori maqasid shariah dalam menjelaskan posisi tradisi pernikahan mengikuti Kyai, karena teori maqasid al-nikah dan maqasid shariah. Peneliti berargumen bahwa tradisi pernikahan mengikuti Kyai memberikan advokasi perlindungan kepada calon pengantin dalam mencapai tujuan pernikahan dan tujuan syariat yang timbul akibat pernikahan.

Kata Kunci: pernikahan taat kyai, maqasid shariah,
HAPPY FAMILY ("SAKINAH" ) OF TAHFID PESANTREN ALUMNI: Marriage Counseling Approach
Authors: Machmudz Machmudz
Published: March 2023

This article is a result of a qualitative field research. This article discusses efforts to form a sakinah family. The research location is Jombang Regency. The data of this research are alumni of Madrasatul Qur'an Islamic boarding school Tebuireng Jombang who are domiciled in Jombang Regency. This study concludes that marriage counseling to maintain household harmony, one of which can be done independently through istiqamahan interacting with the Qur'an. This argument is based on data from the family of alumni who have memorized the Koran PP. Madrasataul Qur'an Tebuireng in Diwek district, Jombang. The alumni practice the routine of memorizing the Qur'an, always remembering Allah (taqarrub), tadarus Al-Qur`an every day, praying in congregation, being open between family members. The alumni carry out several family functions, namely educational, religious, protective, economic, and recreational functions.

Keywords: marriage counseling, happy family, pesantren alumni.

 

Abstrak

Artikel ini adalah hasil penelitian kualitatif lapangan. Artikel ini mendiskusikan upaya membentuk keluarga sakinah. Lokasi penelitian berada Kabupaten Jombang. Data penelitian ini adalah alumni pondok pesantren Madrasatul Qur’an Tebuireng Jombang yang berdomisili di Kabupaten Jombang. Penelitian ini menyimpulkan bahwa konseling pernikahan untuk menjaga keharmonisan rumah tangga salah satunya dapat dilakukan secara mandiri melalui keistiqamahan berinteraksi dengan Al-Qur’an. Argumen ini didasarkan pada data Keluarga alumni penghafal Al-Qur`an PP. Madrasataul Qur`an Tebuireng di kecamatan Diwek Jombang. Para alumni mempraktekkan rutinitas menghafal Al-Qur`an, selalu bedzikir kepada Allah (taqarrub), tadarus Al-Qur`an setiap hari, shalat berjamaah, bersikap terbuka antar anggota keluarga. Para alumni menjalankan beberapa fungsi keluarga, yakni fungsi edukatif, religi, protektif, ekonomis, dan rekreatif.

Kata Kunci: konseling perkawinan, keluarga bahagia, alumni pesantren.
Off-target effects in CRISPR/Cas9 gene editing
Authors: Guo Congting , Ma Xiaoteng , Gao Fei , Guo Yuxuan
Published: March 2023

Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence. With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising translational studies and clinical trials for both genetic and non-genetic diseases. A major concern in the applications of the CRISPR/Cas9 system is about its off-target effects, namely the deposition of unexpected, unwanted, or even adverse alterations to the genome. To date, many methods have been developed to nominate or detect the off-target sites of CRISPR/Cas9, which laid the basis for the successful upgrades of CRISPR/Cas9 derivatives with enhanced precision. In this review, we summarize these technological advancements and discuss about the current challenges in the management of off-target effects for future gene therapy.
3D models of glioblastoma interaction with cortical cells
Authors: Abedin Md Joynal , Michelhaugh Sharon K. , Mittal Sandeep , Berdichevsky Yevgeny
Published: March 2023

Introduction: Glioblastoma (GBM) invasiveness and ability to infiltrate deep into the brain tissue is a major reason for the poor patient prognosis for this type of brain cancer. Behavior of glioblastoma cells, including their motility, and expression of invasion-promoting genes such as matrix metalloprotease-2 (MMP2), are strongly influenced by normal cells found in the brain parenchyma. Cells such as neurons may also be influenced by the tumor, as many glioblastoma patients develop epilepsy. In vitro models of glioblastoma invasiveness are used to supplement animal models in a search for better treatments, and need to combine capability for high-throughput experiments with capturing bidirectional interactions between GBM and brain cells.

Methods: In this work, two 3D in vitro models of GBM-cortical interactions were investigated. A matrix-free model was created by co-culturing GBM and cortical spheroids, and a matrix-based model was created by embedding cortical cells and a GBM spheroid in Matrigel.

Results: Rapid GBM invasion occurred in the matrix-based model, and was enhanced by the presence of cortical cells. Little invasion occurred in the matrix-free model. In both types of models, presence of GBM cells resulted in a significant increase in paroxysmal neuronal activity.

Discussion: Matrix-based model may be better suited for studying GBM invasion in an environment that includes cortical cells, while matrix-free model may be useful in investigation of tumor-associated epilepsy.
2D-nanomaterials for AKI treatment
Authors: Chen Qiaohui , Wang Xiaoyuan , Yuan Chao , Nan Yayun , Huang Qiong , Ai Kelong
Published: March 2023

Acute kidney injury has always been considered a sword of Damocles over hospitalized patients and has received increasing attention due to its high morbidity, elevated mortality, and poor prognosis. Hence, AKI has a serious detrimental impact not only on the patients, but also on the whole society and the associated health insurance systems. Redox imbalance caused by bursts of reactive oxygen species at the renal tubules is the key cause of the structural and functional impairment of the kidney during AKI. Unfortunately, the failure of conventional antioxidant drugs complicates the clinical management of AKI, which is limited to mild supportive therapies. Nanotechnology-mediated antioxidant therapies represent a promising strategy for AKI management. In recent years, two-dimensional (2D) nanomaterials, a new subtype of nanomaterials with ultrathin layer structure, have shown significant advantages in AKI therapy owing to their ultrathin structure, large specific surface area, and unique kidney targeting. Herein, we review recent progress in the development of various 2D nanomaterials for AKI therapy, including DNA origami, germanene, and MXene; moreover, we discuss current opportunities and future challenges in the field, aiming to provide new insights and theoretical support for the development of novel 2D nanomaterials for AKI treatment.
The progress in the relationship between trace elements and acute lymphoblastic leukemia
Authors: Wang Jing , Huang Pei , Lang Changhui , Luo Yan , He Zhixu , Chen Yan
Published: March 2023

Trace elements are very important substances with low content in the human body. If the content of some trace elements changes, they are also related to diseases. Acute lymphoblastic leukemia (ALL) is a malignant blood tumor, and its relationship with trace elements has also been a concern by scholars. Not only have the trace element levels in ALL patients changed, but the efficacy of different treatment methods has also been linked to the corresponding trace element changes. The characteristics of ALL may be related to the dysregulation of differentiation and proliferation of lymphoid precursor cells. Cell proliferation and differentiation are often affected by changes in DNA levels. However, trace elements are involved in DNA damage and repair mechanisms. In recent years, as an increasing number of studies believe that ALL is related to the abnormal metabolism of trace elements in the body, this paper intends to discuss the research progress on the relationship between trace elements and ALL to provide more information on trace elements for the diagnosis, treatment, and prevention of ALL.
Novel TiO2/GO/M-MMT nano-heterostructured composites exhibiting high photocatalytic activity
Authors: Li W. , He Y. , Bao W. B. , Bao H. L. , Li D. Y. , Zhang C. L. , Wang M.
Published: March 2023

This study proposed a technique to enhance the photocatalytic properties of TiO2 using graphene oxide (GO) and modified Montmorillonite (M-MMT). TiO2/GO/M-MMT nano-heterostructured composites were prepared via hydrothermal and co-precipitation. The photocatalytic performance was evaluated by investigating the photodegradation rate and absorption behavior of methyl orange (MO) under visible light irradiation. The results showed that TiO2/GO/M-MMT heterojunction exhibited excellent photocatalytic degradation performance, as the degradation rate of MO was observed to be 99.3% within 150 min. The density of adsorbed MO decreased by 62.1% after 210 min of dark adsorption using the TiO2/GO/M-MMT composite, which was significantly higher than that achieved using M-MMT, GO/M-MMT, and TiO2/M-MMT. The nano-heterostructure increased the effective interface between TiO2, GO, and MMT, which increased the charge transfer ability and prolonged the electron-hole separation time. Therefore, the results of this study can be used to design novel photocatalysts to eradicate environmental pollutants.
Prognostic impact of white blood cell counts on clinical outcomes in patients with chronic renal insufficiency undergoing percutaneous coronary intervention
Authors: Yan Wei , Li Mengyao , Lei Yumeng , Zhang Shuaiyong , Lv Fengfeng , Wang Jiawang , Yang Qian , Yu Na , Chen Ming , Cao Xufen , Yan Liqiu
Published: March 2023

Objective

To determine whether the inclusion of white blood cell (WBC) counts in the SYNTAX score (SS) or SS II models could improve the models’ performance for risk stratification in individuals with chronic renal insufficiency (CRI) following percutaneous coronary intervention (PCI).

Methods

In total, 2,313 patients with CRI, who were subjected to PCI and had data available on in-hospital WBC (ih-WBC) counts, were recruited. Patients were divided into 3 groups as per their ih-WBC counts (low, medium, and high). The primary endpoints were all-cause mortality (ACM) and cardiac mortality (CM). The secondary endpoints incorporated myocardial infarction, stroke, unplanned revascularization, and major adverse cardiovascular and cerebrovascular events (MACCEs).

Results

During a median follow-up of 3 years, the high WBC group had the highest incidences of CM (2.4% vs. 2.1% vs. 6.7%; p < 0.001), ACM (6.3% vs. 4.1% vs. 8.2%; p < 0.001), unplanned revascularization (8.4% vs. 12.4% vs. 14.1%; p < 0.001), and MACCEs (19.3% vs. 23.0% vs. 29.2%; p < 0.001) among the three groups. Multivariable Cox regression analysis depicted that the risk of ACM and CM in the high WBC group was 2.577 (95% confidence interval [CI]: 1.504–4.415, p < 0.001) and 3.850 (95% CI: 1.835–8.080, p < 0.001) times that in the low WBC group after adjusting for other confounding factors. A combination of ih-WBC counts with SS or SS II significantly improved the risk assessment and prediction of ACM and CM.

Conclusion

The ih-WBC counts was associated with the risk of occurrence of ACM, CM, unplanned revascularization, and MACCEs in individuals with CRI following PCI. It provides an incremental predictive value for the occurrence of ACM and CM when included in SS or SS II models.
The link between immunity and hypertension in the kidney and heart
Authors: Benson Lance N. , Guo Yunping , Deck Katherine , Mora Christoph , Liu Yunmeng , Mu Shengyu
Published: March 2023

Hypertension is the primary cause of cardiovascular disease, which is a leading killer worldwide. Despite the prevalence of this non-communicable disease, still between 90% and 95% of cases are of unknown or multivariate cause (“essential hypertension”). Current therapeutic options focus primarily on lowering blood pressure through decreasing peripheral resistance or reducing fluid volume, but fewer than half of hypertensive patients can reach blood pressure control. Hence, identifying unknown mechanisms causing essential hypertension and designing new treatment accordingly are critically needed for improving public health. In recent years, the immune system has been increasingly implicated in contributing to a plethora of cardiovascular diseases. Many studies have demonstrated the critical role of the immune system in the pathogenesis of hypertension, particularly through pro-inflammatory mechanisms within the kidney and heart, which, eventually, drive a myriad of renal and cardiovascular diseases. However, the precise mechanisms and potential therapeutic targets remain largely unknown. Therefore, identifying which immune players are contributing to local inflammation and characterizing pro-inflammatory molecules and mechanisms involved will provide promising new therapeutic targets that could lower blood pressure and prevent progression from hypertension into renal or cardiac dysfunction.