bluuebunny/crossref_metadata_2025 huggingface dataset:
Neoplasias cutâneas em hospital de referência em Campos dos Goytacazes: integração dos registros e sua interface com a política em saúde
Authors: Almeida Ana Paula Moura de , Shimoda Eduardo
Published: February 2023

Dada sua importância e multidimensionalidade, a saúde ocupa lugar de destaque na área de políticas públicas. O câncer de pele é o tipo de neoplasia mais frequentemente encontrado no Brasil e é considerado um problema de saúde pública. Neste sentido, a presente pesquisa aborda a temática do câncer de pele, sendo realizado um diagnóstico da sua incidência no município de Campos dos Goytacazes – RJ, por meio do Registro Hospitalar de Câncer (RHC). Esses registros obtiveram dados de todos os pacientes atendidos em um hospital de referência (Hospital Escola Álvaro Alvim), que apresentavam diagnóstico confirmado do câncer de pele entre os anos de 2012 e 2017, totalizando 656 casos. Através da análise estatística descritiva de variáveis como idade, profissão, local do tumor, bairro e sexo foi possível traçar um perfil dos pacientes acometidos pelo câncer de pele no município, detectando setores da área onde a população local é mais afetada pela doença, além de fatores ambientais que possam estar relacionados e a raça mais acometida. Os resultados do estudo evidenciam que a população de pele clara (69,1%) e a faixa etária acima de 55 anos de idade (com idade predominante dos 70 a 74 anos para os carcinomas basocelulares e dos 80 a 84 anos para os carcinomas espinocelulares), configuram o grupo mais acometido pelo câncer de pele. As informações obtidas desses registros seriam capazes de auxiliar nas políticas públicas e campanhas junto à população, visando melhorar as estratégias para sua prevenção e diagnóstico precoce.
Agroindústrias rurais, políticas públicas e desenvolvimento regional: um perfil da agroindustrialização brasileira com base nos dados do Censo Agropecuário 2017
Authors: Gazolla Marcio , Demétrio Milena , Fantin Leidiane Maria , Borelli Ivanderson
Published: February 2023

O objetivo deste trabalho foi analisar os dados da agroindústria rural (AGR) do Censo Agropecuário 2017, de forma a construir um perfil das experiências no Brasil, nas macrorregiões e nos dois tipos de agriculturas (familiar - AF e não familiar - ANF). A metodologia utilizada foi quantitativa, se utilizando dos dados sobre agroindústria rural do Censo Agropecuário 2017, obtidos no site do Instituto Brasileiro de Geografia e Estatística (IBGE), a partir do Sistema Automático de Recuperação de Dados (SIDRA). Os resultados e conclusões apontam para um perfil de AGRs mais presente nos estabelecimentos da AF, embora os maiores valores de produção e de venda estejam na ANF. As AGRs da AF possuem maiores valores de sua produção que é autoconsumida pelas famílias e menores escalas de produção em relação as AGRs da ANF. A Região Nordeste é a que possui maior número de AGRs, nos dois tipos de agriculturas, enquanto o Sudeste possui maiores valores de produção e de vendas e o Sul maior autoconsumo. Dada a importância da atividade das agroindústrias para o fornecimento de alimentos saudáveis e sustentáveis aos consumidores, caberia ao Estado destinar mais apoio com políticas públicas a estas inciativas, no sentido de aumentar sua autonomia de gestão, gerar mais ocupações e renda e construir melhores mercados para as experiências.
Las Patronas y su construcción de agencia en torno a la migración centroamericana de tránsito por México
Authors: Poblete Fanny Margot Tudela , Pacheco Jesús Antonio Madera
Published: February 2023

En un contexto donde las políticas migratorias son cada vez más severas para limitar la movilidad de gente de bajos o nulos recursos que viajan de un país a otro sin documentos de migración “requeridos” para trabajar o escapar de circunstancias de violencia, opera fuertemente la discriminación, criminalización y violencia hacia tales personas; pero, como contrapeso, también surgen colectivos de la sociedad civil que construyen redes de apoyo hacia quienes migran en situación de vulnerabilidad. Con información obtenida a través de una etnografía multisituada y tomando como referencial analítico la capacidad de agencia y la experiencia, propuestas por Norman Long, en este artículo se presenta el caso de Las Patronas y sus acciones en torno a la migración centroamericana de tránsito por México. estas mujeres, están transformando la realidad no solo de los migrantes en tránsito, también de su comunidad. A partir de sus acciones en pro de los migrantes de paso se han convertido poco a poco en centro de atención (y ejemplo a seguir) para otros colectivos, voluntarios e incluso instituciones a nivel nacional e internacional; de ahí que, poco a poco, su comunidad se ha visto beneficiada por acciones de ellas y de agentes externos.
Redes transnacionales de cuidados y nuevas ciudadanías
Authors: Burgaleta Elena , Garzón-Sherdek Karen
Published: February 2023

El fenómeno de la  feminización de la migración requiere ser analizado desde múltiples perspectivas. En los últimos años se ha incrementado la presencia de las mujeres migrantes en el mercado laboral, convirtiéndose en suministradoras económicas en sus hogares y generando importantes remesas para sus países de destino. Sin embargo, este tipo de migración tiene afectaciones diferenciadas por el hecho de ser mujeres, migrantes y por los estereotipos sociales. El proceso de feminización de la migración y concretamente las cadenas transnacionales de cuidado y apoyo están generando, no sólo de redes   relacionales de trabajo (formal e informal)  y redefiniciones de las relaciones de género, sino también un nuevo espacio de reflexión en la (re)conceptualización de la ciudadanía, como ciudadanía universal transversalizada por el género y la cultura y desvinculada de conceptos como el territorio o la nación.  En este artículo se propone una reflexión sobre las cadenas de cuidado como eje articulador de un espacio económico y especialmente político imprescindible para la reconceptualización de una ciudadanía universal, resultado de un proceso dinámico, heterogéneo e inclusivo.
Movimentos sociais e a Lei de Migração (Lei n° 13.445/2017) na sociedade complexa: caminhos para a legitimação democrática de políticas migratórias contra-hegemônicas no ordenamento jurídico brasileiro
Authors: Dias da Costa Lyra José Francisco , Rotta Diego
Published: February 2023

Este artigo analisa a importância dos movimentos sociais na construção de um novo arcabouço de políticas migratórias no Estado brasileiro. Pergunta-se pela participação dos movimentos sociais na elaboração da Lei nº 13.445/2017, enquanto diploma legal fundado numa lógica contra-hegemônica de direitos humanos e legitimamente democrático. O texto é construído a partir da abordagem dialética, utilizando como procedimentos metodológicos a pesquisa bibliográfica (produção teórica atinente ao tema) e documental (Constituição da República Federativa do Brasil de 1988, Estatuto do Estrangeiro e Lei de Migração), submetidos à técnica da análise de conteúdo. Parte-se do contexto de complexificação das migrações internacionais e da elaboração de políticas migratórias a partir da funcionalidade. Destaca-se a importância dos movimentos sociais na reivindicação e construção de novos direitos, na busca da emancipação dos migrantes enquanto grupo minoritário na sociedade complexa e no processo de repactuação do contrato social. Considerando o cenário de políticas migratórias no Estado brasileiro e os modelos estabelecidos pelo Estatuto do Estrangeiro (Lei nº 6.815/1980) e pela Lei de Migração, (Lei nº 13.445/2017), entende-se que o último diploma legal marca um quadro de políticas migratórias pautadas em uma lógica contra-hegemônica de direitos humanos, estabelecendo direitos e garantias que viabilizam a emancipação dos migrantes enquanto sujeitos de direito. A Lei de Migração, enquanto fruto de trabalho conjunto de especialistas na temática e dos grupos e movimentos sociais defensores dos direitos dos migrantes, garante um processo de legitimação democrática, gestando, também, a possibilidade de participação dos migrantes na repactuação e reelaboração das políticas migratórias.
Migração, raça e a questão regional no Brasil: uma leitura da contribuição de Giralda Seyferth
Authors: Butzke Luciana , Theis Ivo Marcos , Santos Nelson Afonso Garcia
Published: February 2023

O objetivo desse artigo é analisar a atualidade da contribuição de Giralda Seyferth aos estudos sobre migração e raça em sua relação com a questão regional no Brasil. Giralda Seyferth (1943-2017) foi historiadora e antropóloga e se dedicou aos estudos sobre colonização, campesinato, imigração, nacionalismo e racismo. Quanto ao método, recorremos à pesquisa bibliográfica, com uma análise das publicações da autora sobre os temas migração, raça e desenvolvimento regional. Na leitura de sua obra é possível identificar, na construção das regiões Norte e Sul do Brasil, no século XIX, a diferenciação entre os nacionais e os alienígenas, e o racismo intrínseco ao processo migratório estimulado na região Sul. Na formação do Brasil, é possível constatar como a produção das diferenças regionais se deu a partir dos diversos ciclos do capitalismo periférico brasileiro e da funcionalidade da escravização de africanos e africanas e da imigração alemã ao capital. Na obra de Giralda Seyferth transparece a incorporação da raça e do racismo, o seu uso na construção da Nação e a sua presença na fragmentação do território em regiões.
Índice Multidimensional de Proteção Trabalhista (IMPT): uma proposição metodológica
Authors: Bagolin Izete Pengo , Dias do Prado Altevir
Published: February 2023

Diante da escassez de indicadores que permitam análises comparativas entre países e regiões o objetivo deste artigo é propor um índice multidimensional de proteção trabalhista utilizando dados de 152 países. Busca-se, assim, instrumentalizar o debate sobre a proteção versus flexibilização. A metodologia para construção do IMPT foi inspirada em Sartoris (2003) e Hoffmann (1998) e o índice – IMPT - varia entre zero e um e permite ranquear os países a partir das legislações trabalhistas vigentes. Os resultados mostram que o IMPT oscilou entre 0,182 para a Suazilândia e 0,729 para a Eslovênia. Os EUA, geralmente considerado um exemplo de mercado flexível, ficou na posição 143, com um IMPT de 0,243 e o Brasil obteve índice de 0,583, que caracteriza um país com proteção/flexibilidade média.
Análisis económico de la producción de semilla gámica de Tithonia diversifolia (Hemsl.) Gray en Cuba
Authors: Báez Quiñones Nadia , Padilla César , Rodríguez García Idalmis , Ruíz Tomás E.
Published: February 2023

La Tithonia diversifolia es una de las plantas proteicas más aceptada por los ganaderos en Cuba para alimentar a los animales. Encontrar una alternativa económica para fomentar sistemas de producción con esta planta es vital para disminuir los costos asociados a la plantación e indirectamente en la alimentación, por lo que el objetivo de este trabajo fue determinar qué método de propagación (por semilla vegetativa o gámica) de tithonia resulta económicamente más factible para la producción de semilla gámica en las condiciones de Cuba. Se determinaron las fichas de costo de la producción de semilla gámica de tithonia a partir de plantaciones por vía asexual. Luego, a partir de este valor se determinó el costo de producción de la semilla gámica sembrada por vía sexual. El costo de producción de la semilla gámica fue de 15.07 USD/kg cuando se sembró con material vegetativo, y de 11.04 USD/kg cuando se usó semilla gámica. Se demuestra que el costo de establecimiento de una hectárea de tithonia para la producción de semillas se reduce hasta 3 veces cuando se parte del uso de semilla gámica, comparado al uso de semilla vegetativa (US$ 142.13 vs 472.05, respectivamente).
Periodic combustion regimes for thermally coupled SHS systems with a thermocapillary melt flow
Authors:   Tomsk State University, Prokof’ev Vadim G.
Published: February 2023

This paper presents a three-dimensional mathematical model of self-propagating high-temperature synthesis (SHS) of a three-layer “sandwich” sample. The layers are formed from gasless mixtures with the addition of an inert fusible component. The mathematical model is studied numerically using the finite-difference method. The unsteady periodic regimes of gasless combustion of the three-layer sample with square cross-section are revealed with account for melting and thermocapillary flow of the melted inert component of the mixture. The unsteady periodic combustion regimes are specified depending on the relative calorific value of the mixture in the inner layer. High-temperature points move along the side faces of the sample. The velocity of the points’ motion along the combustion surface is much higher than the average burning velocity of the sample. An increase in the melt flow velocity leads to the equalization of the temperature field and stabilization of the combustion regime. The quasi-stationary regimes of control and fusion are studied during the combustion of the sample with an active inner layer, when the intrinsic burning velocities of the donor and acceptor mixtures are close to each other.
An experimental study of the ultrasound effect on the motion of glass spherules in Hele-Shaw cells
Authors:   Ufa Federal Research Center of the Russian Academy of Sciences, Rakhimov Artur A. , Valiev Azat A. ,   Ufa Federal Research Center of the Russian Academy of Sciences
Published: February 2023

This paper presents the experimental study results for the effect of ultrasound influence (USI) on the filling of the Hele-Shaw cells with glass spherules at a constant pressure drop, including the case with a stepwise constriction. The process considered represents a physical model of fractures in an oil reservoir. The experimental set-up is developed with the use of visualization methods for microfluidic studies. Exposure to the USI and constant pressure drop provides the close packing and uniform distribution of the spherules. The flow rate of the water with glass spherules, which are sieved through a 150 pm strainer in the measured model with a thickness of 200 pm, increases proportionally with an increase in the pressure drop, while for the model with the spherules sieved through a 70 pm strainer, the increase is more significant, and the flow rate is five times lower for a pressure drop of 50 kPa. The USI is revealed to be crucial for the uniform filling with the spherules, both in the volumetric models with and without constriction. When the spherules block the constriction, the USI reactivates the flow. Thus, it is a reliable method of influencing the dynamic blocking effect, which is promising for creating the technology intended to increase the ratio of hard-to-recover oil reserves in the total production balance.
A critical appraisal of public-private-partnership as a financial model and critical success factors in aviation sector in Turkey
Authors: Unvan Yuksel Akay , Ozdemir Muhsin Tamer
Published: February 2023

Purpose- Due to the complexity and high-tech nature of airport projects, their completion takes a substantial amount of time and cost, posing significant financial hurdles for governments. In recent decades, infrastructure finance challenges are increasingly being met through the Public-Private Partnership (PPP) model, which brings together public and private sectors to build and maintain public facilities. This study provides an overview of the PPP model and the major stakeholders in its implementation. In addition, the financial structuring of PPP projects and the financial instruments typically employed in PPP model is also highlighted. Besides, it is aimed to discuss the critical success factors of PPP model in airport projects in Turkey.
Methodology- In this study, the charactheristics of PPP model, its associated stakeholders and the financial structure of PPP projects are highlighted through a review of literature and it is aimed to determine and classify the critical success factors of PPP model in airport projects in Turkey.
Findings- PPP project contracts need to address the adequate sharing of risk, profit, and the costs associated with making new investments. In the study, the macro-level and project-level critical success factors are determined through a review of literature and classified into 7 sub-groups.
Conclusion- In a general sense, a PPP project is considered successful if its objectives are met and its stakeholders are satisfied with the results. Besides, taking into consideration the significant EBITDA profitability of PPP airport projects in Turkey, the government’s partnership in the SPV companies with a public minority share is proposed in order to make it possible for the public to get its share of the profit and to gain more control over these companies. In this model, since the government is involved in the project as an active actor with its legislative power and expertise, the resilience, transparency, and profitability of the project will increase, and both sides may benefit more from the PPP project.

Keywords: Public-private-partnership, aviation industry, critical success factors, airport investments
JEL Codes: L93, R42, G20, H81
ESG scores relationship with firm performance: panel data evidence from the European tourism industry
Authors: Demiraj Rezart , Dsouza Suzan , Demiraj Enida
Published: February 2023

Purpose – This paper aims to investigate if there is a significant relationship between corporate ESG (environmental, social, and governance) scores and firm profitability (ROA) and whether this relationship is positive, negative, or neutral.
Methodology – The study examines all listed companies from the European tourism industry for which ESG scores are available. The final sample consists of 48 firms from 14 European countries and 258 firm-year observations, obtained through the Refinitiv database for the period from 2010 to 2019. Panel regression analysis was used to examine the relationship between ESG scores (independent variable) and ROA (dependent variable), including financial leverage and firm size as control variables as well.
Findings – The results show that ESG scores are negatively related to firm performance as measured by ROA and such a relationship is statistically significant at 5%. Higher levels of ESG scores are associated with lower levels of ROA and vice-versa.
Conclusion –The findings suggest that instead of just trying to give the appearance of being ESG-oriented, it is important for companies to actually implement proper ESG practices and standards. Also, in order to promote the adoption of environmental, social, and governance (ESG) practices by companies, it is crucial to educate the public about the long-term benefits of these practices and encourage support for companies that follow these standards.

Keywords: ESG score, tourism, profitability, Europe.
JEL Codes: G30, Q56, Z33.
Relationship of banking sector and environmental performance in Turkey
Authors: Akyuz Gulay Cizgici
Published: February 2023

Purpose- With the global financial crisis in 2008, financial institutions have brought up the importance of the evaluation of the relationship between the environment and financial performance and its role in its development. In particular, examining the effects of environmental policies on the factors such as financial development, economic growth and financial performance is among the research subjects of researchers. In this respect, the aim of this study is to examine the relationship between the financial performance of the banking sector and environmental performance in Turkey.
Methodology- While examining the effect of environmental performance on the financial performance of the banking sector, annual data for the period between 1990-2019 have been used, and short- and long-term relationships between the variables have been established by the ARDL bound test and the causality relationship has been established by the Toda-Yamamoto causality test. Return on assets (ROA) has been used as the financial performance indicator of the banking sector and carbon dioxide emission (CO2) as the environmental performance indicator in the study. In addition, deposits, loans and liquid assets have been used as control variables in the study.
Findings- In the model established with the ARDL cointegration test in the study, it has been first investigated whether the variables are cointegrated in the long-term, and it has been concluded that the variables are cointegrated in the long-term. In the established ARDL model, it has been determined that carbon dioxide emissions have a positive effect on the financial performance of the banking sector in the long-term, but not in the short-term. In addition, it has been determined that deposits and liquid assets, the control variables, have a positive effect on financial performance both in the short- and long-term, while loans do not have any effect. The findings from the results of the Toda-Yamamoto causality test reveal a one-way positive causality relationship from carbon dioxide emissions and deposits to banking financial performance. Moreover, while a positive two-way causality relationship has been established between financial performance and liquid assets, no causality relationship has been found with loans.
Conclusion- The results of the cointegration test and the causality test confirm each other. The findings show that an increase in CO2 emissions will lead a positive effect on the financial performance of banks. Consequently, it is thought that developing countries such as Turkey are increasingly addicted to non-renewable energy consumption and adopt a more flexible environmental policy and so that they provide a higher financial performance. With this result, the opinion that the Pollution Paradise hypothesis is valid for Turkey is supported.

Keywords: Financial performance, environmental performance, ARDL, Toda-Yamamoto
JEL Codes: C32, G21, O13
Decentralize finance and new lending protocols
Authors: Kaplan Betul , Benli Vahit Ferhan , Alp Elcin Aykac
Published: February 2023

Purpose- Satoshi Nakamoto initially proposed the most well-known blockchain technology application after financial crisis in 2008 as the technology underlying Bitcoin, a virtual currency exchanged within a peer-to-peer network. To fill the trust gap between parties willing to exchange value, new applications have been developed through the blockchain in many different commercial industries, following in the footsteps of Bitcoin. Blockchain has countless potential uses and benefits, but like other innovations such as the World Wide Web, its adoption is a gradual and hard process that is always evolving. In this regard, the academic literature focuses mostly on the technical aspects of the it while the study of its business-related challenges is still in its infancy. By providing a framework that outlines the new lending procedures and its economic potential, study aims to participate the academic literature on finance applications of blockchain in banking sector.
Methodology- To obtain the results of the returns of S&P 500 and DeFi assets, the methodology involves an analysis of decentralized finance assets through a framework that explains the outlining the lending protocols in decentralized finance and a comparison of centralized finance vs. decentralized finance.
Findings- Blockchain technology and smart contracts are two components of the decentralized finance (DeFi) movement, which aims to establish a decentralized, open, and accessible financial system. Unlike traditional financial systems, which are centralized, opaque, and often difficult to access, DeFi is open to anyone with an internet connection. One of the key areas of DeFi is lending and borrowing, where users can exchange cryptocurrencies with fixed or variable interest rates without the need for a central authority or intermediary. Additionally, DeFi eliminates the need for credit history checks and third-party verification because loans are granted based on excessive collateral or other methods of ensuring repayment. The use of blockchain technology also increases the efficiency of transactions and reduces transaction costs.
Conclusion- This study discusses the concept of decentralized finance (DeFi), which is an innovative way of delivering financial services through blockchain technology. It allows for peer-to-peer transactions to be conducted remotely and securely and is considered a paradigm shift in the financial industry. Currently, DeFi mostly replicates traditional financial services, but as it continues to expand, new and innovative applications are emerging. The growth and evolution of DeFi is dependent on factors such as the characteristics of blockchain technology, legal standards, and cultural differences between traditional and decentralized finance. In the future, it is expected that DeFi will continue to grow and potentially disrupt traditional financial institutions.

Keywords: Banking, decentralized finance, blockchain, lending protocols, peer-to-peer lending
JEL-Codes: G23, G14, O31
The relationship between exchange rate volatility and inflation in Turkey
Authors: Kara Huseyin , Dede Yunis
Published: February 2023

Purpose- Many studies pointing out that the exchange rate depreciations underlies of the inflation problem, which is still keep up to-date, provides empirical evidences about the existence of a direct relationship between the exchange rate and domestic prices. In addition to this phenomenon called exchange rate pass-through, we also think that exchange rate volatility can also have an impact on domestic prices. The aim of this study is to investigate the relationship between inflation and exchange rate volatility, which is characterized by the increase in risks and the creation of an environment of uncertainty in Turkish economy.
Methodology- In our study, we run an augmented philips curve equation to estimate the effect of exchange rate volatility and other variables on inflation. We measure exchange rate volatility as the standard deviation and GARCH (1,1), which are frequently used in the literature. In addition, we use the time-varying parameter approach to estimate the direction in which the effect of exchange rate volatility on inflation changes over time.
Findings- According to the findings, the parameters in the philips curve equation are statistically significant and reasonable in line with the economic theory. The coefficient of inflation inertia is estimated to be 0.33. This indicates that approximately one-third of a 1% increase in inflation comes from past inflation. The ERPT is calculated as 18% for the short term and 27% for the long term. The fact that the exchange rate volatility parameters are statistically significant confirms our hypothesis. Accordingly, an increase of 1 conditional standard deviation in exchange rate volatility leads to an increase in domestic prices by 0.71. We also provide evidences that the impact of both exchange rate and exchange rate volatility on inflation increases over time.
Conclusion- The results show that, in addition to the exchange rate, exchange rate volatility also has a significant effect on inflation. This provides credible evidences that exchange rate uncertainty should be an additional indicator, such as the exchange rate, to achieve price stability and monetary policy goals.

Keywords: Exchange rate volatility, exchange rate pass-through, inflation, time-series models, monetary policy
JEL Codes: E31, C32, E52
Measuring financial reporting quality of non-financial firms listed in Amman Stock Exchange
Authors: Alahmad Mohammad , Teker Dilek
Published: February 2023

accuracy and transparency is vital for internal and external users, this study insures that financial reporting quality and financial information published for non-financial firms in ASE is not manubulated, accurate, combitable, timely published, adequate, and free of earning management, to be usefull for decision making for all users, especially for new investors.
Methodology- The period 2010 – 2019 forms the data for the statistical analysis. In addition, and to measure the FRQ, the paper uses time series analysis techniques, including descriptive analysis, frequencies and multiple OLS regression were used. Using data from 910 firm-years observation of companies listed on Amman Stock Exchange for the period of 2010 to 2019.
Findings- The analysis reveals that The probability for F-Statistics < 0.05, this led to accept the statistical model. on the other hand, R square is 31.3 % which means that the explanatory power of modified Jones model (Dechow et al., 1995) reach 31.3% in explain the practices of earnings management in Jordanian companies. on the other hand, the VIF values are lower than 10 and tolerances higher than 10% which mean there is no multicollinearity problem in the model. as for the 1/A_(i,t-1) shows a significant and negative relationship with total accruals, were 〖∆(Sales-AR)〗_it/A_(i,t-1) and 〖PPE〗_it/A_(i,t-1) 1/A_(i,t-1) shows a significant and positive relationship with total accruals.
Conclusion- the highest number of companies practicing earnings management in the year (2012 and 2014) was 60%, while the lowest number of companies that practice earnings management in the year (2015) and it was 32%, on the other hand, the highest number of companies do not practicing earnings management in the year (2015) was 68%, while the lowest number of companies that do not practice earnings management in the year (2012 and 2014) and it was 40%.

Keywords: FRQ, modified jones model, Amman Stock Exchange, non-financial firms
JEL Codes: G10, G12
Hydrophobic Polyvinylidene Fluoride Membrane Modified with Silica Nanoparticles and Silane for Succinic Acid Purification Using Osmotic Distillation Process
Authors:   Centre for Sustainable Process Technology, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Tan Jun Ying , Ang Wei Lun ,   Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia, Mohammad Abdul Wahab ,   Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia
Published: February 2023

Recently, osmotic distillation (OD) has emerged as an alternative process for the concentration and purification of heat sensitive components. However, OD performance was severely affected by membrane fouling and wetting, which could be minimized through membrane surface roughness creation and surface energy modification. This study incorporated silica nanoparticles and coated tridecafluro-1,1,2,2-tetrahydrooctyl-1-triethoxysilane at various concentration onto polyvinylidene fluoride (PVDF) membrane to improve its hydrophobicity, limiting the contact between foulants in feed solution and membrane surfaces. Generally, the addition of silica reduced the water contact angle (WCA) of the membrane, but the inclusion of silane had increased it. These membranes were then tested through OD with 1 wt% succinic acid feed solution and 50 wt% calcium chloride stripping solution. PVDF membranes that have been modified with 1 wt% silica nanoparticles and coated with 1:50 volume ratio silane solution achieved a transmembrane flux of 0.6019 kg/m2⋅h, the highest flux among silanated membrane. This was due to the larger pore size retained after silanization. A rejection rate of 95.66% and above were achieved by the membranes fabricated in this study. Overall, PVDF membrane modified with silica and silane had been successfully utilized in OD process and shown potential as a concentration and purification process.
Computational Fluid Dynamics Simulation of Fluidized Bed Dryer for Sago Pith Waste Drying Process
Authors:   Research Centre for Sustainable Process Technology (CESPRO), Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Malaysia, Abdul Nasir Abdul Mu’im , Rosli Masli Irwan ,   Research Centre for Sustainable Process Technology (CESPRO), Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Malaysia, Takriff Mohd Sobri ,   Research Centre for Sustainable Process Technology (CESPRO), Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Malaysia, Ali Othman Nur Tantiyani ,   Research Centre for Sustainable Process Technology (CESPRO), Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Malaysia, Ravichandar Vinotharan ,   Chemical Engineering Program, Faculty of Engineering & Built Environment, Universiti Kebangsaan Malaysia, Malaysia
Published: February 2023

Sago pith waste (SPW) has a great potential in becoming numerous kinds of reusable products as it has high level of starch content after went through drying process. Without proper treatment the disposal of SPW could cause serious environmental problem. The drying process of SPW using fluidized bed dryer (FBD) was found to be more effective than other drying methods. Thus, in this study the process was analyzed using computational fluid dynamics (CFD) modelling with the developed three-dimensional FBD model. The fluidization profile was studied from the analysis done using ANSYS Fluent 19.2 software which include certain process flow and set up to create similar situation as the experimental condition by also taking into account the moisture content of SPW. Both approach of drying process were executed at air inlet temperature of 50ºC and velocity at 1.50 ms-1. Using the sample of SPW that initially at 40% wet basis the result of fluidization from experimental and simulation were comparable in term of particles profiles and percentage of moisture content which show closely resemblance of decreasing trend. The outcome was however having a slight different of moisture content at 15th minute of experimental approach which could be resolved by improving the model in term of zone condition of the simulation setup. This study is however is an initial part to study about SPW drying using CFD solution as there are more to be discovered with this advantageous tool that is able to perform and provide much more analysis and outcomes in much shorter time and cost saving way base on the experimental method.
The Correlation of Peculiarities of Ethnic Identity and Living Conditions on the State of Volitional Regulation among Tuvans
Authors: Shlyapnikov V.N.
Published: February 2023

The article presents the results of a study of the correlation of living conditions and ethnic identity on the state of volitional regulation among Tuvans living in various regions of the Russian Federation. The study involved 431 people aged 18 to 45 from Erzin (185 people), Kyzyl (141 people) and Moscow (105 people). To evaluate the individual characteristics of volitional regulation in the respondents, the following techniques were used: the Action Control Scale by J. Kuhl; the "Questionnaire for revealing the expression of self-control in the emotional sphere, activity and behavior"; the technique for self-assessment of volitional qualities; the Purpose in Life Test. The features of ethnic identity were evaluated using the “Types of Ethnic Identity” technique (by S.V. Ryzhova, G.U. Soldatova). The results of a one-way ANOVA allow us to conclude that the differences in the state of volitional regulation among Tuvans living in rural and urban settlements in the case of the "Action control scale" and social self-control are due mainly to the characteristics of the ethnic identity of the respondents, and in the case of emotional and behavioral self-control - peculiarities of ethnic identity of the respondents and living conditions in the region.
Representation of Oneself and Others in a Transitional Society: Intergenerational Analysis
Authors: Demidov A.A. , Ananyeva K.I. , Samba A.D.-B.
Published: February 2023

The article examines the problem of the dynamics of psychological attitudes of the individual to himself and to other people in the context of the socio-cultural transformation of the living environment. The example of the Republic of Tuva shows the socio-cultural transformation for different age generations of Tuvans. The article presents the results of an empirical study of the attitude of Tuvans living in a remote area of ​​the Republic of Tuva, of different ages, towards themselves and other people - representatives of the Tuvan and Russian ethnos of different age generations. It is shown that, in the perceptions of Tuvan respondents of different age groups, there are “nuclear” qualities, characteristics, with the help of which representatives of their ethnic group are described in comparison with representatives of the Russian ethnic group.
Features of damage to the ribs by a blade with a defective tip
Authors: Gurov Vladislav D. , Klevno Vladimir A.
Published: February 2023

Stab wounds are a common injury in the practice of a forensic pathologist. Such damage often occurs in domestic conditions, for example, in the kitchen during a quarrel, where knives are always at hand. The young, able-bodied portions of the population are frequent victims, which makes the problem socially significant.
Knives that have been used for a long time are rarely in perfect condition; operational defects occur on them. For example, repeated sharpening results in the rounding of the tip of the blade. Moreover, during operation, the tip of the blade can bend or even break off. However, before studying the effects of such blades on flat bones, studying the history of this issue, to familiarize with the work of other scientists, is necessary.
In the literature review, authors of studies on stab-cut injuries focused more on damage to the skin and clothing. Morphological features of skeletal bone injuries and the possibility of identification studies on them until the XXI century were described poorly.
To improve the forensic medical diagnosis of rib injuries caused by blades with point defects based on the study of a complex of morphological features, experimental studies on cadaveric materials are necessary.
“Kazan Medical Journal” — the successor of the “Diaries of the Physicians’ Society” at the Imperial Kazan University
Authors: Sozinov Alexey S. , Ziganshin Ayrat U. , Ivanov Anton Yu. , Ivanova Regina G.
Published: February 2023

The article defines the structural specifics of the scientific periodicals of the Kazan Physicians Society, characterizes the logic of its evolution, shows its place in the development of the general logic of qualitative changes in the methods of constructing and manifesting medical knowledge broadcast on its pages. The stages of the evolutionary transformation of the Diaries of the Physicians Society, which were the printed organ of the Physicians Society at the Imperial Kazan University, into a special edition the Kazan Medical Journal are analyzed in detail, the date of its official approval as a printed organ is specified. Based on the materials of the State Archives of the Republic of Tatarstan, many of which were not previously introduced into scientific circulation, the succession of the development of scientific periodicals was demonstrated, which makes it possible to reasonably indicate 1872 as the year when the Kazan Medical Journal started to be published. The article gives a brief description of the published volumes of this stage of the transformation of the Diaries of the Physicians Society, indicates the specifics of their formal, as well as content and, in particular, intertextual structure. The role and place of various types of published materials, such as original scientific articles, abstracts of current scientific literature of that time, annual literature reviews in various medical specialties, meeting reports of representatives of scientific societies, reports of medical congresses and the so-called doctoral disputes at Kazan University at that time, reports of practical health care institutions of Kazan, special correspondence, reviews of scientific works, scientific bibliography, were determined. An analysis of these elements evolution in the content of scientific periodicals made it possible to substantiate the logical model of the structural transformation of this printed organ as a special type of historical source, to determine the forms of its cultural and communicative functioning, to indicate its role in the development of the professional culture of the medical corporation of Kazan University and the city of Kazan.
Expression of microRNA-590 in patients with chronic coronary heart disease, atrial fibrillation, and their combination
Authors: Lerner Dina D. , Mayanskaya Svetlana D. , Kravtsova Olga A. , Tambovtseva Regina S.
Published: February 2023

Background. The role of microRNAs in the processes of remodeling, proliferation, and fibrogenesis of myocardial cells is not clear enough.
Aim. Analysis of the microRNA-590 expression level in patients with chronic coronary heart disease, atrial fibrillation, as well as their combination to assess the potential prognostic significance of the expression level.
Material and methods. The study included 94 patients divided into three clinical groups: the first with non-valvular atrial fibrillation without coronary heart disease (39 people); the second with non-valvular atrial fibrillation and coronary heart disease (22 patients); the third with ischemic heart disease without atrial fibrillation (23 patients). The comparison group consisted of 10 people without atrial fibrillation and coronary heart disease. Venous blood was taken from all subjects, from the plasma of which microRNA was isolated. The relative level of microRNA expression was estimated based on real-time polymerase chain reaction data obtained during the reaction on a cycler using commercial TaqMan probes and primers. The statistical significance of differences between groups was determined using one-way analysis of variance, followed by post-hoc analysis using Tukey's contrasts, differences were considered statistically significant at p 0.05. The ShapiroWilk test was used to assess the normality of the distribution of residuals.
Results. A statistically significant decrease in the expression level of microRNA-590 was registered in the third (p=0.0104) and in the second (p=0.0046) groups compared with the control group, as well as in patients with atrial fibrillation and left atrial dilatation (p=0.0313), with recurrent arrhythmias after radiofrequency ablation (p=0.0083) and with permanent atrial fibrillation (p=0.0242).
Conclusion. Ischemic heart disease, including when combined with atrial fibrillation, and aggravating factors, such as left atrial dilatation, permanent atrial fibrillation, recurrence of arrhythmia after radiofrequency ablation, lead to a decrease in the expression level of microRNA-590.
The influence of exogenic lactoferrin on DNA methylation in postimplantation mouse embryos developed from zygotes exposed to bisphenol A
Authors: Postnikova Liubov A. , Noniashvili Ekaterina M. , Suchkova Irina O. , Baranova Tatyana V. , Patkin Eugene L.
Published: February 2023

BACKGROUND: Bisphenol A is a chemical agent ubiquitous in plastic consumer products and a toxin capable of disrupting key epigenetic mechanisms in early embryogenesis. It becomes more and more clear that early development changes in epigenetic pathways caused by exposure to toxic substances are associated with various adult diseases. Therefore the need to identify new agents capable of eliminating epigenetic mechanisms failures caused by the bisphenol A toxin becomes evident. Here we suggest lactoferrin as a normalizer of toxicant-induced epigenomic changes. Currently there is no data on the role of lactoferrin as a normalizer of epigenomic disorders under the influence of toxicants. We assume that in mammalian embryogenesis lactoferrin might function as an epigenetic modulating factor.
AIM: The aim of the research is to study effects of lactoferrin on the epigenetic status of postimplantation mouse embryos, exposed to bisphenol A in utero.
MATERIALS AND METHODS: In this study, 3 experimental groups of mice and two control group were used. 1. Mice on the first day of pregnancy, injected with 40 mg/kg of body weight of bisphenol A; 2. Mice on the first day of pregnancy, injected with 50 mg/kg of body weight of lactoferrin; 3. Mice on the first day of pregnancy, successively injected with 50 mg/kg body weight of lactoferrin and 40 mg/kg of body weight of bisphenol A. On the 15th day of embryonic development, the level of genome-wide DNA methylation was evaluated in different body parts of the embryos by methyl-sensitive restriction and ImageJ visualization analysis.
RESULTS: We demonstrated that in post-implantation mouse embryos, exposure to bisphenol A in the prenatal period caused an increased level of genome-wide DNA methylation. The most prominent effects were observed in brain and abdominal section of the embryos. Together, the present findings confirmed that lactoferrin administration at a dose of 50 mg/kg of body weight resulted in normalization of genome-wide DNA methylation levels after bisphenol A-induced epigenetic alterations.
CONCLUSIONS: We assume that lactoferrin may partially neutralize the harmful effects of bisphenol A caused aberrant methylation, and thus can potentially be used as a pharmaceutical product. Factual findings of the present study may help by development of new therapeutic approaches. Nevertheless, further research of the bisphenol A, lactoferrin and lactoferrin + bisphenol A effects on reactive oxygen species and/or antioxidant enzymes is needed.
Mytilus edulis hydrolysate enhances proliferation and protects endothelial cells against hypochlorous acid-induced oxidative stress
Authors: Starikova Eleonora A. , Mammedova Jennet T. , Porembskaya Olga Ya.
Published: February 2023

BACKGROUND: Endothelial dysfunction underlies the pathogenesis of many socially significant diseases. The search for new original drugs for the treatment of this condition remains an important scientific and practical task. Anti-inflammatory, anticoagulant and antioxidant effects of bivalve mollusks from the family of mussels (Mytilus edulis) hydrolysate and its derivatives have been described in different model systems.
AIM: The purpose of this study was to investigate the effect of M. edulis hydrolysate on the functional activity of EA.hy926 endothelial cell line.
MATERIALS AND METHODS: The viability and metabolic activity of endothelial cells were studied in MTT-test. To investigate the proliferative activity, a test with staining of cells with crystal violet dye was used. The ability of the preparation to neutralize the toxic effect of HOCl and H2O2 was evaluated using fluorescent dyes and flow cytometry.
RESULTS: It was found that the preparation did not have cytotoxicity and significantly increased the proliferation of endothelial cells in dilutions from 1:10 to 1:60. The preparation had a neutralizing effect against HOCl, and in all the studied dilutions significantly increased the viability of the endothelium. The preparation was not effective against H2O2, and increased H2O2 toxic effect in the maximal studied concentration. At the same time, the anti-inflammatory effect of M. edulis hydrolysate was not confirmed in this model system. The preparation had no effect on the IL-8 production and adhesion molecule CD54 (ICAM-1) and tissue factor CD146 the expression.
CONCLUSIONS: The preparation of M. edulis hydrolysate enhances the proliferation of endothelial cells and is able to neutralize HOCl toxic effects.