bluuebunny/crossref_metadata_2025 huggingface dataset:
A IMPORTÂNCIA DA PRESCRIÇÃO DOS ÁCIDOS GRAXOS DE ÔMEGA 3 COMO TRATAMENTO ADJUVANTE EM MULHERES PORTADORAS DA SÍNDROME DOS OVÁRIOS POLICÍSTICOS (SOP)
Authors: Cavalcanti Jéssica Tamyris de Freitas
Published: March 2022

Introdução: A síndrome dos ovários policísticos (SOP) é um distúrbio de ordem endócrino que acomete em sua maioria mulheres na idade reprodutiva. A sua etiologia não é totalmente elucidada, porém é responsável por causar várias desordens de saúde das pacientes, tais como: infertilidade, alterações no ciclo menstrual, cistos no ovário, resistência a insulina e demais alterações metabólicas. Por muito tempo a única terapêutica proposta era o uso de contraceptivos hormonais orais que podem vir a aumentar a ocorrência de doenças de ordem cardiovasculares. Objetivo: Estudar e demonstrar a importância da prescrição do ômega 3 como um adjuvante na terapêutica farmacológica das mulheres portadoras de SOP. Métodos: Revisão bibliográfica, de obras literárias, que foi realizada entre os meses de outubro e dezembro do presente ano de 2021, com artigos que trouxessem uma abordagem ao tema gerador desse mesmo estudo “A importância da prescrição dos ácidos graxos de Ômega 3 como tratamento adjuvante em mulheres portadoras da síndrome dos ovários policísticos. Os artigos foram buscados nas bases de dados, Biblioteca Virtual em Saúde (BVS), Literatura Internacional em Ciências da Saúde (Pubmed, Medline), Scientific Eletronic Library (SCIELO) a partir dos termos utilizados relacionados ao assunto principal e ao foco requerido no estudo. Resultados: A terapia farmacológica da SOP, atualmente os anticoncepcionais orais estão sendo substituídos pelos agentes sensibilizadores de insulina no tratamento da SOP, devido aos seus efeitos sobre a resistência à insulina e o risco cardiovascular. A ingestão dos ácidos graxos do ômega 3 pode induzir à melhora da função endotelial promovendo a liberação de óxido nítrico das células endoteliais, diminuir a pressão arterial sistólica e diastólica em repouso pela incorporação de EPA e DHA nos fosfolipídios da membrana. Estudos demonstram que a suplementação com ômega 3, tende a minimizar implicações no desenvolvimento de Diabetes Melittus tipo 2, Conclusão: As evidências analisadas no estudo, demonstram a importância da suplementação do ômega 3 promovendo resultados positivos para a atenuação e prevenção de desenvolvimento de doenças vasculares ateroscleróticas e o risco do aparecimento de Diabetes Mellitus tipo 2.
ENTENDENDO A FORMAÇÃO DOS DEPÓSITOS AMILOIDES DAS DOENÇAS PRIÔNICAS POR MEIO DA BIOINFOMÁTICA
Authors: Lima Gabriely Crivari De Almeida , Hassunuma Renato Massaharu , Garcia Patrícia Carvalho
Published: March 2022

Introdução: Doenças priônicas são causadas por proteínas dobradas incorretamente, denominadas Proteínas Priônicas com Scrapie (PrPSc). Estas proteínas são formadas a partir do dobramento incorreto de Proteínas Priônicas Celulares (PrPC). As PrPSc se depositam no sistema nervoso central, formando depósitos amiloides semelhantes aos observados em outras doenças degenerativas do sistema nervoso central, como a doença de Parkinson, a doença de Huntington e a doença de Alzheimer. Objetivos: A presente pesquisa teve objetivo utilizar recursos de Bioinformática para desenvolver scripts para o software RasMol 2.7.4.2, para comparar a estrutura bioquímica da PrPC e PrPSc humanas. Material e métodos: A partir do levantamento de arquivos 1QM2.pdb e 6LNI.pdb, referentes às PrPC humana e PrPSc humana, foram desenvolvidos scripts para o software RasMol 2.7.4.2, com a finalidade de comparar a estrutura tridimensional destas proteínas. Resultados: A partir dos scripts produzidos, foi possível observar que o arquivo 1QM2.pdb apresenta um fragmento da PrPC, que contém os resíduos 126 a 228, onde são observadas três alfa-hélices e duas fitas beta. O arquivo 6LNI.pdb apresenta um fragmento da PrPSc, formado pelos resíduos 171 a 229, onde se observam 6 fitas beta. Neste mesmo arquivo, foi possível desenvolver um script, que mostra uma fibrila amiloide de PrPSc, formada a partir de sua polimerização, por meio da interação entre as PrPSc vizinhas. Conclusão: Desta forma, foi possível observar que, na PrPSc, ocorrem mudanças em seu dobramento e sua estrutura secundária, que passa a apresentar um maior número de fitas beta. Essa nova conformação estrutural leva à polimerização das PrPSc, formando os depósitos amiloides em doenças priônicas. Assim sendo, o estudo dos eventos moleculares que ocorrem no dobramento incorreto da PrPSc pode abrir novos caminhos para futuras pesquisas sobre a etiopatogenia das doenças degenerativas do sistema nervoso central.
Politik Hedefleri Açısından Amerikan Evanjelizmi ve Osmanlı Devleti’ndeki Faaliyetleri
Authors: Akyüzoğlu İlyas
Published: March 2022

Amerikalı Evanjelikler, fundamentalist yaklaşımları ile bilinen İngiliz Püriten cemaatinin devamıdırlar. Günümüzde ise ABD’deki sayısal-siyasal olarak en büyük, güçlü ve etkili Hristiyan grubu oluşturmaktadırlar. Bu güçleri sayesinde Amerikan siyasetini etkileyebilmekte ve dış politikasına yön verebilmektedirler. Dini bir tarikat olmalarına rağmen kıyamete dair görüşleri dolayısıyla agresif siyasetçiler olarak da nitelenmektedirler. Çünkü İncil’de yer alan eskatolojik kehanetlerin siyaset aracılığıyla gerçekleşebileceğine inanmaktadırlar. Bu kehanetlerin gerçekleşeceği yer Osmanlı coğrafyasıdır. İsa Mesih kıyamet öncesi Ortadoğu’da meydana gelecek olan büyük türbülans/bunalım sonrası yeryüzüne tekrar geri gelecek ve Hristiyan ordusunun başına geçip kafirleri Armageddon savaşında mağlup ederek Cennet Krallığı’nı tesis edecektir. Evanjelikler de bu kehanetlerin gerçekleşmesi için kendilerini adamış kesin inançlılardır. Çalışmada Evanjeliklerin temel inanışları ve Osmanlı coğrafyasına duydukları ilginin nedenleri ele alınmıştır. Ayrıca bu hedefler doğrultusunda Osmanlı coğrafyasında yürüttükleri faaliyetler ve bunların doğurduğu siyasi/sosyal sonuçlar örnekleriyle beraber ortaya konulmaya çalışılmıştır.
Forecasting Models of The Regions’ Development Potential
Authors: KARMOWSKA Grażyna , Sobczyk Andrzej , Marjak Henryk
Published: March 2022

To assess and plan the development potential of a region, tools for forecasting and simulation of that development are needed. The choice of the model class used for forecasting purposes depends on: the nature of forecast, available information, research questions and the nature of the forecast variable.
How to update the Securitization Regulation?
Authors: ZOMBIRT Jolanta
Published: March 2022

Some years after the subprime crisis, regulators started to change their thinking about securitization having noticed its advantages. At first, their efforts to create a more friendly environment for securitization were rather shy. A true acceleration of these efforts could be seen after COVID-19 and its devastating effects on banks’ balance sheets and the real economy.
On the Way to Intelligent Infrastructure
Authors: Прозоров А. , Шнырев Р. , Волков Д.
Published: March 2022

Использование ИИ при разработке и эксплуатации киберфизических систем потенциально может помочь решить проблему сложности ИТ-инфраструктур и существенно повысить скорость создания ПО.

The use of AI in development and operation of cyberphysical systems can offer a potential way to address the IT infrastructure complexity issue while significantly accelerating software creation.
Dinamika ibadah gereja menggunakan Daring dimasa pandemi Covid-19 berdasarkan Ibrani 10:25
Authors: Pandiangan Kingston , Hutagalung Stimson , Ferinia Rolyana
Published: March 2022

Pandemi Covid-19 telah mengubah model perbaktian. Perbaktian daring menjadi pilihan yang terbaik untuk meminimalisasi penularan Covid-19. Oleh sebab itu, peneliti ingin mengetahui apakah anggota jemaat siap mengikuti kebaktian daring? Tujuan penelitian ini untuk mengetahui sejauh mana visi, misi gereja, minat, interaksi sosial, dan teknologi dapat diimplementasikan oleh anggota jemaat. Metode penelitian ini adalah kualitatif dengan pendekatan deskriptif. Langkah-pertama yang dilakukan adalah membagikan kuesioner kepada 52 anggota jemaat sebagai populasi untuk mendapatkan gambaran implementatif Ibrani 10:25 yang dihubungkan dengan ibadah daring dengan menggunakan SPSS 24 untuk analisis deskriptifnya. Langkah kedua adalah melakukan kajian literatur untuk membahas tentang Ibrani 10:25 secara teologis dan langkah ketiga adalah menyandingkan hasil kuesioner dengan kajian literatur. Kesimpulan adalah anggota gereja menerima ibadah daring dan tetap dapat melakukan interaksi sosial dalam menguatkan dan menasehati sekalipun melalui proses pembelajaran menggunakan gadget. Anggota menyadari sepenuhnya bahwa dengan daring pengabaran Injil lebih mudah dan meluas ke seluruh dunia.
Atmospheric composition in the European Arctic and 30 years of the Zeppelin Observatory, Ny-Ålesund
Authors: Platt Stephen M. , Hov Øystein , Berg Torunn , Breivik Knut , Eckhardt Sabine , Eleftheriadis Konstantinos , Evangeliou Nikolaos , Fiebig Markus , Fisher Rebecca , Hansen Georg , Hansson Hans-Christen , Heintzenberg Jost , Hermansen Ove , Heslin-Rees Dominic , Holmén Kim , Hudson Stephen , Kallenborn Roland , Krejci Radovan , Krognes Terje , Larssen Steinar , Lowry David , Lund Myhre Cathrine , Lunder Chris , Nisbet Euan , Nizzetto Pernilla B. , Park Ki-Tae , Pedersen Christina A. , Aspmo Pfaffhuber Katrine , Röckmann Thomas , Schmidbauer Norbert , Solberg Sverre , Stohl Andreas , Ström Johan , Svendby Tove , Tunved Peter , Tørnkvist Kjersti , van der Veen Carina , Vratolis Stergios , Yoon Young Jun , Yttri Karl Espen , Zieger Paul , Aas Wenche , Tørseth Kjetil
Published: March 2022

Abstract. The Zeppelin Observatory (78.90∘ N, 11.88∘ E) is located on Zeppelin Mountain at 472 m a.s.l. on
Spitsbergen, the largest island of the Svalbard archipelago. Established in
1989, the observatory is part of Ny-Ålesund Research Station and
an important atmospheric measurement site, one of only a few in the high
Arctic, and a part of several European and global monitoring programmes and
research infrastructures, notably the European Monitoring and Evaluation
Programme (EMEP); the Arctic Monitoring and Assessment Programme (AMAP); the
Global Atmosphere Watch (GAW); the Aerosol, Clouds and Trace Gases
Research Infrastructure (ACTRIS); the Advanced Global Atmospheric Gases
Experiment (AGAGE) network; and the Integrated Carbon Observation System
(ICOS). The observatory is jointly operated by the Norwegian Polar Institute
(NPI), Stockholm University, and the Norwegian Institute for Air Research
(NILU). Here we detail the establishment of the Zeppelin Observatory
including historical measurements of atmospheric composition in the European
Arctic leading to its construction. We present a history of the measurements
at the observatory and review the current state of the European Arctic
atmosphere, including results from trends in greenhouse gases,
chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs), other
traces gases, persistent organic pollutants (POPs) and heavy metals,
aerosols and Arctic haze, and atmospheric transport phenomena, and provide
an outline of future research directions.
Global emissions of perfluorocyclobutane (PFC-318, c-C4F8) resulting from the use of hydrochlorofluorocarbon-22 (HCFC-22) feedstock to produce polytetrafluoroethylene (PTFE) and related fluorochemicals
Authors: Mühle Jens , Kuijpers Lambert J. M. , Stanley Kieran M. , Rigby Matthew , Western Luke M. , Kim Jooil , Park Sunyoung , Harth Christina M. , Krummel Paul B. , Fraser Paul J. , O'Doherty Simon , Salameh Peter K. , Schmidt Roland , Young Dickon , Prinn Ronald G. , Wang Ray H. J. , Weiss Ray F.
Published: March 2022

Abstract. Emissions of the potent greenhouse gas perfluorocyclobutane
(c-C4F8, PFC-318, octafluorocyclobutane) into the global atmosphere
inferred from atmospheric measurements have been increasing sharply since
the early 2000s. We find that these inferred emissions are highly correlated
with the production of hydrochlorofluorocarbon-22 (HCFC-22, CHClF2) for
feedstock (FS) uses, because almost all HCFC-22 FS is pyrolyzed to produce
(poly)tetrafluoroethylene ((P)TFE) and hexafluoropropylene (HFP), a process
in which c-C4F8 is a known by-product, causing a significant
fraction of global c-C4F8 emissions. We find a global emission
factor of ∼0.003 kg c-C4F8 per kilogram of HCFC-22 FS
pyrolyzed. Mitigation of these c-C4F8 emissions, e.g., through
process optimization, abatement, or different manufacturing processes, such
as refined methods of electrochemical fluorination and waste recycling,
could reduce the climate impact of this industry. While it has been shown
that c-C4F8 emissions from developing countries dominate global
emissions, more atmospheric measurements and/or detailed process statistics
are needed to quantify c-C4F8 emissions at country to facility
levels.
A strong statistical link between aerosol indirect effects and the self-similarity of rainfall distributions
Authors: Furtado Kalli , Field Paul
Published: March 2022

Abstract. We use convective-scale simulations of monsoonal clouds to reveal a self-similar probability density function that underpins surface rainfall statistics. This density is independent of cloud-droplet number concentration and is unchanged by aerosol perturbations. It therefore represents an invariant property of our model with respect to cloud–aerosol interactions. For a given aerosol concentration, if the dependence of at least one moment of the rainfall distribution on cloud-droplet number is a known input parameter, then the self-similar density can be used to reconstruct the entire rainfall distribution to a useful degree of accuracy. In particular, we present both single-moment and double-moment reconstructions that are able to predict the responses of the rainfall distributions to changes in aerosol concentration. In doing so, we show that the seemingly high-dimensional space of possible aerosol-induced rainfall-distribution transformations can be parameterised by surprisingly few (at most 3) independent “degrees of freedom”: the self-similar density and auxiliary information about two moments of the rainfall distribution. Comparisons to convection-permitting forecasts of mid-latitude weather and atmosphere-only global simulations show that the self-similar density is also independent of model physics and background meteorology. A theoretical explanation for this invariance is given, based on numerical results from a stochastic rainfall simulator. This suggests that, although aerosol indirect effects on any specific hydro-meteorological system may be multifarious in terms of rainfall changes and physical mechanisms, there may, nevertheless, be a universal constraint on the number of independent degrees of freedom needed to represent the dependencies of rainfall on aerosols.
Sea ice changes in the southwest Pacific sector of the Southern Ocean during the last 140 000 years
Authors: Jones Jacob , Kohfeld Karen E. , Bostock Helen , Crosta Xavier , Liston Melanie , Dunbar Gavin , Chase Zanna , Leventer Amy , Anderson Harris , Jacobsen Geraldine
Published: March 2022

Abstract. Sea ice expansion in the Southern Ocean is believed to have contributed to
glacial–interglacial atmospheric CO2 variability by inhibiting air–sea gas exchange and influencing the ocean's meridional overturning circulation. However, limited data on past sea ice coverage over the last 140 ka (a complete glacial cycle) have hindered our ability to link sea ice expansion to oceanic processes that affect atmospheric CO2 concentration. Assessments of past sea ice coverage using diatom assemblages have primarily focused on the Last Glacial Maximum (∼21 ka) to Holocene, with few quantitative reconstructions extending to the onset of glacial Termination II (∼135 ka). Here we provide new estimates of winter sea ice concentrations (WSIC) and summer sea surface temperatures (SSST) for a full glacial–interglacial cycle from the southwestern Pacific sector of the Southern Ocean using the modern analog technique (MAT) on
fossil diatom assemblages from deep-sea core TAN1302-96. We examine how the
timing of changes in sea ice coverage relates to ocean circulation changes
and previously proposed mechanisms of early glacial CO2 drawdown. We
then place SSST estimates within the context of regional SSST records to
better understand how these surface temperature changes may be influencing
oceanic CO2 uptake. We find that winter sea ice was absent over the
core site during the early glacial period until MIS 4 (∼65 ka), suggesting that sea ice may not have been a major contributor to early
glacial CO2 drawdown. Sea ice expansion throughout the
glacial–interglacial cycle, however, appears to coincide with observed
regional reductions in Antarctic Intermediate Water production and
subduction, suggesting that sea ice may have influenced intermediate ocean
circulation changes. We observe an early glacial (MIS 5d) weakening of
meridional SST gradients between 42 and 59∘ S throughout
the region, which may have contributed to early reductions in atmospheric
CO2 concentrations through its impact on air–sea gas exchange.
Artemisia pollen dataset for exploring the potential ecological indicators in deep time
Authors: Lu Li-Li , Jiao Bo-Han , Qin Feng , Xie Gan , Lu Kai-Qing , Li Jin-Feng , Sun Bin , Li Min , Ferguson David K. , Gao Tian-Gang , Yao Yi-Feng , Wang Yu-Fei
Published: March 2022

Abstract. Artemisia, along with Chenopodiaceae is the dominant component growing in the desert and dry grassland of the Northern Hemisphere. Artemisia pollen with its high productivity, wide distribution, and easy identification, is usually regarded as an eco-indicator for assessing aridity and distinguishing grassland from desert vegetation in terms of the pollen relative abundance ratio of Chenopodiaceae/Artemisia (C/A). Nevertheless, divergent opinions on the degree of aridity evaluated by Artemisia pollen have been circulating in the palynological community for a long time. To solve the conclusion, we first selected 36 species from 9 clades and 3 outgroups of Artemisia based on the phylogenetic framework, which attempts to cover the maximum range of pollen morphological variation. Then, sampling, experiments, photography, and measurements were taken using standard methods. Here, we present pollen datasets containing 4018 original pollen photographs, 7200 statistical pollen morphological traits, information on 30858 source plant occurrences, and corresponding environmental factors. Hierarchical cluster analysis on pollen morphological traits was carried out to subdivide Artemisia pollen into three types. When plotting the three pollen types of Artemisia onto the global terrestrial ecoregions, different pollen types of Artemisia were found to have different habitat ranges. These findings change the traditional concept of Artemisia being restricted to arid and semi-arid environments. The data framework that we designed is open and expandable for new pollen data of Artemisia worldwide. In the future, linking pollen morphology with habitat via these pollen datasets will create additional knowledge that will increase the resolution of the ecological environment in the geological past. The Artemisia pollen datasets are freely available at Zenodo (https://doi.org/10.5281/zenodo.5842909; Lu and Jiao, 2022).
Assessing the impacts of tropical cyclones on rice production in Bangladesh, Myanmar, Philippines, and Vietnam
Authors: Yuen Kai Wan , Switzer Adam D. , Teng Paul P. S. , Lee Janice Ser Huay
Published: March 2022

Abstract. Information on agriculture-related damage and losses in Asia is under-reported in major multi-peril disaster databases. National disaster databases in some countries may have information on agricultural losses, but this information is not always available. We address this knowledge gap by creating a database of cyclone-induced rice damage from 1970–2018 for four major rice producing countries in Asia which experience frequent and intense tropical cyclones as a result of their geographical location (Philippines, Vietnam, Bangladesh, and Myanmar). We collated information using online news sources on rice damage locations, rice area damaged, loss in rice production, and loss in rice value from 1970–2018. Of the 1,046 cyclone events recorded, 138 events were associated with rice damage and loss, and majority of these events (93 %) happened in the Philippines and Vietnam. The average area of rice damaged per cyclone event ranged from 42,407 ha in Vietnam to 423,075 ha in Myanmar. The average rice production loss per cyclone event ranged from 460,667 metric tonnes in Bangladesh to 2,943,088 metric tonnes in the Philippines. Losses in rice production value from 1970–2018 were only reported in the Philippines and amounted to an average of US$42 million per cyclone event. Although Category 4 events tend to cause the most damage, tropical storms and Category 1 events were more frequent, especially in Vietnam. While our study is limited by the availability and quality of online news sources, we provide an assessment of rice agricultural damage from tropical cyclones in major rice producing countries in Asia.
Rare earth elements associated with carbonatite–alkaline complexes in western Rajasthan, India: exploration targeting at regional scale
Authors: Aranha Malcolm , Porwal Alok , Sundaralingam Manikandan , González-Álvarez Ignacio , Markan Amber , Rao Karunakar
Published: March 2022

Abstract. A two-stage fuzzy inference system (FIS) is applied to prospectivity modelling and exploration-target delineation for rare earth element (REE) deposits associated with
carbonatite–alkaline complexes in the western part of the state of Rajasthan in India. The design of the FIS and selection of the input predictor
map are guided by a generalised conceptual model of carbonatite–alkaline-complex-related REE mineral systems. In the first stage, three FISs are
constructed to map the fertility and favourable geodynamic settings, favourable lithospheric architecture for fluid transportation and favourable
shallow crustal (near-surface) emplacement architecture, respectively, for REE deposits in the study area. In the second stage, the outputs of the
above FISs are integrated to map the prospectivity of REE deposits in the study area. Stochastic and systemic uncertainties in the output
prospectivity maps are estimated to facilitate decision-making regarding the selection of exploration targets. The study led to the identification
of prospective targets in the Kamthai–Sarnu-Dandeli and Mundwara regions, where detailed project-scale ground exploration is
recommended. Low-confidence targets were identified in the Siwana ring complex region, north and northeast of Sarnu-Dandeli, south of Barmer, and
south of Mundwara. Detailed geological mapping and geochemical sampling together with high-resolution magnetic and radiometric surveys are
recommended in these areas to increase the level of confidence in the prospectivity of these targets before undertaking project-scale ground
exploration. The prospectivity-analysis workflow presented in this paper can be applied to the delineation of exploration targets in geodynamically
similar regions globally, such as Afar province (East Africa), Paraná–Etendeka (South America and Africa), Siberia (Russia), East European
Craton–Kola (eastern Europe), Central Iapetus (North America, Greenland and the Baltic region) and the pan-superior province (North America).
Ambient seismic noise analysis of LARGE-N data for mineral exploration in the Central Erzgebirge, Germany
Authors: Ryberg Trond , Kirsch Moritz , Haberland Christian , Tolosana-Delgado Raimon , Viezzoli Andrea , Gloaguen Richard
Published: March 2022

Abstract. Ambient seismic noise tomography is a novel, low-impact
method for investigating the earth's structure. Although most passive seismic
studies focus on structures on crustal scales, there are only a few examples
of this technique being applied in a mineral exploration context. In this
study, we performed an ambient seismic experiment to ascertain the
relationship between the shallow shear wave velocity and mineralized zones
in the Erzgebirge in Germany, one of the most important metal provinces in
Europe. Late Variscan mineralized greisen and veins occurring in the
Geyer-Ehrenfriedersdorf mining district of the Central Erzgebirge were mined
from medieval times until the end of the 19th century. These occurrences
represent a significant resource for commodities of high economic
importance, such as tin, tungsten, zinc, indium, bismuth and lithium. Based
on ambient noise data from a dense “LARGE-N” network comprising 400
low-power, short-period seismic stations, we applied an innovative
tomographic inversion technique based on Bayesian statistics
(transdimensional, hierarchical Monte Carlo search with Markov Chains using
a Metropolis/Hastings sampler) to derive a three-dimensional shear wave
velocity model. An auxiliary 3D airborne time-domain electromagnetic dataset
is used to provide additional insight into the subsurface architecture of
the area. The velocity model shows distinct anomalies down to approximately
500 m depth that correspond to known geological features of the study area,
such as (a) gneiss intercalations in the mica schist-dominated host rock,
imaged by a SW–NE striking low-velocity zone with a moderately steep
northerly dip, and (b) a NW-trending strike-slip fault, imaged as a
subvertical linear zone cross-cutting and offsetting this low-velocity
domain. Similar to the velocity data, the electromagnetic data exhibit
north-dipping (high-conductivity) structures in the mica schists,
corresponding to the strike and dip of the predominant metamorphic fabric.
An unsupervised classification performed on the bivariate 3D dataset yielded
nine spatially coherent classes, one of which shows a high correspondence with
drilled greisen occurrences in the roof zone of a granite pluton. The
relatively high mean shear velocity and resistivity values of this class
could be explained by changes in density and composition during greisen
formation, as observed in other areas of the Erzgebirge. Our study
demonstrates the great potential of the cost-efficient and low-impact
ambient noise technology for mineral exploration, especially when combined
with other independent geophysical datasets.
Effective coefficient of diffusion and permeability of firn at Dome C and Lock In, Antarctica, and of various snow types – estimates over the 100–850 kg m−3 density range
Authors: Calonne Neige , Burr Alexis , Philip Armelle , Flin Frédéric , Geindreau Christian
Published: March 2022

Abstract. Modeling air transport through the entire firn column of polar ice sheets is needed to interpret climate archives. To this end, different regressions have been proposed in the past to estimate the effective coefficient of diffusion and permeability of firn. These regressions are often valid for specific depth or porosity ranges only. Also, they constitute a source of uncertainty as evaluations have been limited by the lack of reliable data of firn transport properties.
To contribute with a new dataset, this study presents the effective coefficient of diffusion and the permeability at Dome C and Lock In, Antarctica, from the near-surface to the close-off (23 to 133 m depth). Also, microstructure is characterized based on density, specific surface area, closed porosity ratio, connectivity index, and structural anisotropy through the correlation lengths. All properties were estimated based on pore-scale computations from 3D tomographic images of firn samples. The normalized diffusion coefficient ranges from 1.9 × 10−1 to 8.3 × 10−5, and permeability ranges from 1.2 × 10−9 to 1.1  × 10−12 m2, for densities between 565 and 888 kg m−3. No or little anisotropy is reported.
Next, we investigate the relationship of the transport properties with density over the firn density range (550–850 kg m−3), as well as over the entire density range encountered in the ice sheets (100–850 kg m−3), by extending the datasets with transport properties of alpine and artificial snow from previous studies.
Classical analytical models and regressions from literature are evaluated against the estimates from pore-scale simulations.
For firn, good agreements are found for permeability and the diffusion coefficient with two existing regressions of the literature based on open porosity
despite the rather different site conditions (Greenland).
Over the entire 100–850 kg m−3 density range, permeability is accurately reproduced by the Carman–Kozeny and self-consistent (spherical bi-composite) models when expressed in terms of a rescaled porosity, ϕres=(ϕ-ϕoff)/(1-ϕoff), to account for pore closure, where ϕoff is the close-off porosity.
For the normalized diffusion coefficient, none of the evaluated formulas were satisfactory, so we propose a new regression based on the rescaled porosity that reads D/Dair=(ϕres)1.61.
MENINGKATKAN SUMBER DAYA MANUSIA DESA CIPURUT DALAM MENYONGSONG ERA TEKNOLOGI 4.0
Authors: Lesmana Teddy , Rahmawati Rika , Manan Saepul , Salman Farizi Mohamad , Pudarwati Egit , Apriatna Ami , Pamungkas Ferry Rajib , Agis S.L Adrian , Amalia Nanda Rizki , Aziz Nauval , Sopian Ripki Mohamad , Multiaha Muh Reza , Rivaldi Aqil , Sabila Husnul , Hermawan Rudi , Elis Eva , Fatma Aulia Putri Ulil , Rahayu Anita , Darmawan Panca Adhi , Supardi Redi , Pratama Agung , Julianto Ardi , Anggraeni Luni , Sopandi Ade Solihin , Jamaludin  , Mulkarim Ikram , Kamal. Muhammad Satrio , Muharom Yusuf , Maharani Sri Ayu , Ardiyansyah Rizal A , Aisyah Siti , Maolida Salsabilla Fatimah Maolida , Suherman Egi , Fatma Nurul Yulia
Published: March 2022

To welcome the era of technology 4.0, and there are still many human resources who do not understand how to apply the technology that is currently developing, it is necessary to have socialization and training in the Cipurut Village environment.  With the current condition which is still in the covid-19 pandemic, almost all activities use the internet, such as education and services to the community. With the development of the digital world today, many things, especially those related to educational activities and services to the community, can use the digital system, making it easier and more practical. With many people, especially human resources at the Cipurut village office, who do not yet understand digital technology, it is necessary to have the training and workshops to improve the competence of human resources.As a result of the current use of technology, the existing community can already use it to help their activities, such as online sales, public services, etc. For village officials themselves, they can use digital technology to assist in providing services to the community.
PEMBERDAYAAN MASYARAKATDAN PEMASARAN OLAHAN HASIL ALAM DESA BENCOY
Authors: Rangga Abdurrasyid Muhammad , Abdul Jabbar Muhammad Rifqi , Wardani Neng Resti , Destria Arianti Nunik , Muslih Muhamad
Published: March 2022

The village of bencoy has abundant agricultural potential or natural products so it is very good for improving the community's economy. Agricultural products or natural products owned by an area can be processed into various products, for example chips, rengginang, sale, cilok and so on. Empowerment activities and marketing of natural products are carried out by providing counseling and socialization to communities who have MSMEs and millennial youth farmer members with the aim of providing information and knowledge about processing natural products into various types of processed which are not only for their own enjoyment or consumption but also for family use. made into an effort that can improve the household economy and the village economy.
MELHORIA NA GESTÃO DE ESTOQUES EM UMA EMPRESA DE BRINQUEDOS
Authors: Gisele da Silva Rodrigues Amanda , Rubian De Lima Da Silva Cristhian , Aparecida de Bianchi Michelly , Youssef Antônio , Henrique Lixandrão Fernando Paulo
Published: March 2022

Atualmente para se alcançar os melhores resultados nas organizações, e sair na frente da concorrência, é necessário atentar-se aos detalhes, o que antes não era dado a devida importância, é justamente o grande diferencial nas empresas. Na busca para reduzir os custos com estoques, as organizações vêm diminuindo cada vez mais esta classe de ativos, por isso a gestão e o controle de estoque são de extrema importância. A empresa Brinquedos Estrela S.A vem sofrendo os impactos negativos do acúmulo de estoque, ocasionados devido uma série de fatores, internos e externos, e à falta de gestão e controle, potencializado com a concorrência dos produtos Chineses de preços altamente competitivos. Sendo assim, o objetivo deste trabalho acadêmico é propor soluções de melhoria na resolução da problemática, utilizando-se de ferramentas disponíveis de gestão, tais como: Indicadores Logísticos para estruturar uma Gestão robusta capaz de medir o nível de serviço, entradas e saídas de estoque, custos de armazenagem e previsão de demanda. De maneira a atender a demanda da organização o foco será no planejamento e controle de materiais. Em vista disso a metodologia aplicada a pesquisa será realizada de caráter exploratório e explicativa com base nos levantamentos bibliográficos sendo utilizado métodos experimentais matemáticos e análises quantitativas. Espera- se com o presente trabalho a redução de custos com armazenagem, otimização dos processos, maior controle e organização, identificação de falhas, ameaças e oportunidades de negócio, ganhando assim uma vantagem competitiva no mercado.
Svenska kyrkan och äldres välbefinnande – betydelsen av en församlings öppna verksamheter
Authors: Wulff Hamrin Cornelia , Kusterer Hanna Li , Lundberg Lotta
Published: March 2022

Äldre personers välbefinnande, och hur kyrkan och dess församlingar genom sina öppna verksamheter kan bidra till detta välbefinnande, står i fokus för denna studie. Vi genomförde tretton intervjuer med personer över 65 år som besökt någon öppen verksamhet i en församling i en stad i Mellansverige sommaren 2021. En induktiv tematisk analys resulterade i fem teman: kontakt med andra, fysisk aktivitet, sysselsättning, kyrkan och församlingen samt platser att gå till.
Resultatet visar betydelsen av dessa faktorer för att minska känslan av ensamhet och bryta isolering. Det överensstämmer med tidigare forskning, men pekar också på kyrkans och församlingens potentiella betydelse för att ge äldre personer sammanhang och sysselsättning.
Det finns få studier som har undersökt detta och mer forskning behövs. Det behövs också fler sociala aktiviteter och träffpunkter för äldre i Sverige.
 
The Church of Sweden and the well-being of elderly people – the impact of open activities in a parishThe aim of the present study was to explore factors that contribute to elderly people’s well-being, the impact of the church and their open activities organized by a parish. Thirteen interviews were carried out in a city in mid-Sweden with people over 65 years of age who had participated in an open activity during the summer of 2021. An inductive thematic analysis resulted in five themes: interactions with others, physical activity, keeping occupied, the church and the parish and places to visit.
The result points to the importance of these factors in decreasing loneliness and social isolation. This is in accordance with previous research but highlights the importance of the church and the parish in giving elderly people a social context and a meaningful pursuit.
Few studies have examined this, and more research is needed as well as more activities and meeting points for elderly people in Sweden.
Evidence based Nursing practice: Nurses’ Awareness, Perception and Barriers
Authors: Oommen Sushma , Upasani Saroj V.
Published: March 2022

Today evidence based practice has become a key constituent of outstanding patient care. Understanding of Evidence Based Practice will help in deciding the weightage to be put on particular research, examination, report, clinical practice guidelines while making decision about care of a client. The objective of the study was to explore awareness and perception of nurses regarding evidence-based nursing practice. A survey questionnaire was used to collect data for this study from full time working nurses. Nurses with diploma, university degree certificate and postgraduate degrees participated in studywith experience in various fiels of nursing. Most of them did not receive any special training in evidence-based practice. Majority of nurses agreed that evidence-based practice is based on research findings, individualized patient care and that it is an approach to health care. According to them evidence-based practice helps in the provision of highest quality care. Clinical expertise of nurses, organizational culture to practice, patient preferences were considered as important by most of the nurses. Nurses were even aware of the needs, barriers of evidence-based practice. The study concluded that provision of timely training and facilities to provide evidence-based nursing practice will help in developing confidence among nurses and improve the quality of nursing care.
Augmenting the Tolerance Potential of Muskmelon (Cucumis melo L.) Using Salicylic Acid
Authors: Ullah Ibrar , Rahman Habib Ur , Ullah Kalim
Published: March 2022

Salicylic acid (SA) is considered an important plant hormone that controls many aspects of plant growth and development, as well as resistance to biotic and abiotic stresses. In current investigations, a pot experiment consisting of four different levels of SA (0, 1, 2 and 3 mM SA) were tested on growth and physiological attributes of muskmelon (Cucumis melo L.), grown at different salinity levels (0, 50, 100 mM NaCl). Results revealed that all the morphological and physiological attributes were significantly (P<0.05) adversely affected by salinity stress, whereas application of SA improved growth rate of muskmelon both in saline and non-saline conditions. SA treated plants showed higher total chlorophyll content, photosynthetic rate and stomatal regulations as compared to control plants. SA application reduced the salt deleterious effects by inhibiting toxic Na+ ions accumulation in leaf and increased K+/Na+ ratio. Among the various applied concentrations, 2 mM SA increased shoot fresh weight by (30%), dry weight (34%), leaf area (25%) and K+/Na+ ratio by (84%) as compared to control plants. Thus, 2 mM SA concentration is concluded to be the best ameliorative treatment in salt stressed environments to enhance the muskmelon production.
Wound Healing Potential/Activity of Polyherbal Ointment Containing Salvadora persica, Azadirachta indica and Calendula officinalis Extracts: An Experimental Study
Authors: Imran Hina , Rehman Atiq-ur- , Sohail Tehmina , Shaukat Sohail , Khokar Ayesha
Published: March 2022

The present study explore the wound healing potential of a novel herbal ointment formulation, fast wound healing ointment (FWHO) composed of 10% w/w crude ethanolic extracts of Salvadora persica (sticks), Azadirachta indica (leaves) and Calendula officinalis (whole plant) on excision wound model in albino rats. The FWHO was applied topically once daily on the wound to evaluate the rate of contraction and period of epithelialization in rats. Complete contraction and epithelialization of wound was observed at 19 day (P<0.0005) in test group animals compared with standard (polyfax skin ointment) at 23 day (P<0.0005) and control group (blank petroleum jelly) at 29 day respectively. It was observed that 10% FWHO has potent wound healing capability as evidenced by decrease in the period of epithelialization and increase in the rate of wound contraction in test group as compared to the standard and control groups. The test group illustrates 34.4%, while the standard group shows 20.6% decrease in the time of epithelialization as compare to control group. The study revealed that test ointment (10% FWHO) has a potential to promote wound healing by accelerating the rate of epithelialization and scar formation as compare to standard (polyfax skin ointment) and control (blank petroleum jelly) groups.
In vitro Studies of the Utilization of Industrially Important Substrates by Lactobacillus sp. AAF-1 Isolated from Coconut Water
Authors: Siddiqui Ayesha , Aman Ayisha , Fatima Syeda Areej , Riaz Aliya , Zohra Rashida Rahmat , Naheed Suad
Published: March 2022

Coconut water (Cocos nucifera L.) possesses natural hydrating qualities, functional health  properties and various nutritional benefits. Lactobacillus species AAF-1 has been isolated and purified from coconut water. The isolated culture was screened for the production of extracellular secreted enzymes having industrial value. Growth of the Lactobacillus sp. AAF-1 on MRS agar containing respective substrates showed that the Lactobacillus sp. AAF-1 is the potential producer of amylase, protease, cellulase and beta galactosidase. Further cell free filtrates of the Lactobacillus sp. AAF-1 showed large zone of hydrolysis of starch, gelatin, cellulose and lactose that reflected the extracellular production of the above enzymes in culture medium at 50 °C. It has been observed that activities after 72 h of incubation in cell free filtrates of protease, amylase, cellulase and beta galactosidase as the zone of respective substrate hydrolysis measured as 10, 8, 6 and 10 mm respectively. Thus, Lactobacillus sp. AAF-1 could be the potential producer of the enzymes having industrial value.
Pengaruh Pemakaian Transparent Dressing Terhadap Luka Tekan Pasien Acute Decompensated Heart Failure
Authors: Yuliati Yuliati , Munte Ilona Veronika
Published: March 2022

Acute Decompensated Heart Failure (ADHF) adalah sindrom klinis dengan tanda-tanda atau gejala gagal jantung yang memburuk yang membutuhkan rawat inap dalam waktu lama.  ADHF dipandang sebagai eksaserbasi kronis Heart Failure akibat dari kelebihan volume.  Lamanya tirah baring akan menyebabkan kerusakan integritas kulit, seperti abrasi dan luka tekan. Luka tekan sebagai cedera lokal pada kulit atau jaringan di bawahnya, biasanya di atas penonjolan tulang, atau tekanan kombinasi dengan gesekan. Penelitian ini bertujuan untuk mengidentifikasi pemakaian transparan dressing terhadap luka tekan pasien ADHF. Penelitian ini merupakan penelitian deskriptif kuantitaif dengan metode kuasi eksperimental, yaitu rancangan penelitian yang digunakan untuk mengetahui suatu gejala atau pengaruh yang timbul sebagai akibat dari adanya perlakuan tertentu. Populasi dalam penelitian ini adalah seluruh pasien dengan diagnosa ADHF yang dirawat di ruang Intermediet di RS Jantung Harapan Kita. Teknik pengambilan sampel dengan non-probability sampling dengan teknik accidental sampling yaitu mengambil kasus atau responden yang kebetulan ada atau tersedia sebanyak 40 responden. Intrument yang digunakan lembar observasi skala braden untuk mengobservasi luka tekan NPUAP 2016.  Diperoleh hasil 67,6% laki-laki, kejadian luka tekan berat sebelum intervensi 32,5%, luka tekan sedang 42,5% dan luka ringan 25%. Setelah diberikan intervensi kejadian luka tekan berat menjadi 2,5%, luka tekan sedang 27,5% dan luka tekaan ringan menjadi 70% sehingga dapat disimpulkan adanya pengaruh pemakaian transparent dressingpada kejadian luka tekan pasien ADHF. Penggunaan transparan dressing pada daerah yang tertekan dapat mengurangi derajat luka tekan meluas.
CLINICAL AND FUNCTIONAL OUTCOMES AFTER TWO DIFFERENT ANTERIOR CRUCRIATE LIGAMENT RECONSTRUCTION TECHNIQUES: COMPARISON OF RIGIDFIX AND ENDOBUTTON
Authors: KAFA Nihan , ÇOBANOĞLU Gamze , ULUCAKÖY Coşkun , ATAOGLU Baybars , ATALAY GÜZEL Nevin
Published: March 2022

Background: Endobutton and Rigidfix are the most used fixation methods for anterior cruciate ligament reconstruction (ACLR). No studies were found investigating the superiority of these two methods to each other in terms of laxity, strength, gait and jumping.
Aim: The purpose of this study is to compare laxity, tunnel enlargement, isokinetic strength, gait and jump in cases who had ACLR with Endobutton or Rigidfix techniques.
Method: The study consisted of cases who received ACLR with Endobutton (n=13) and Rigidfix techniques (n=13). Bone tunnel enlargement was assessed on CT serial sections and anterior knee laxity was evaluated using an arthrometer. Quadriceps and Hamstring muscle strengths were measured using isokinetic system. BTS G-walk was used for gait analysis and jumping.
Results: There was no statistically significant difference in anterior knee laxity, tunnel enlargement, isokinetic muscle strength and jump height between two groups. In gait analysis, only uninvolved side stride length and pelvic tilt symmetry index were significantly different between groups (p=0.045; p=0.038 respectively).
Conclusions: In patients with ACLR, whichever type of fixation method was used; all of parameter values were similar. Furthermore, even after two years of surgery, functional differences were detected between the affected and unaffected legs. Also, statistically significant tunnel enlargement was found in both techniques. It was concluded that the recovery to normal condition after ACLR is not fully achieved, regardless of the fixation technique. It can be stated that this situation may cause problems in terms of the structure of the ligament and joint kinematics over time.
Prevalence of Metabolic Syndrome and Their Associated Risk Factors Amongst Adults in District Bahawalpur
Authors: Afzal Kamran , Zeb Nida Gulzar , Humayun Farhat , Hashmi Javed Akthar , Asad Mohammad Rehan , Kamran Ambreen
Published: March 2022

Background: Globally metabolic syndrome is considered as important public health issue because of its association with the higher possibility to develop diabetes and heart problems in children, teenagers, and adults. Objective: To assess the prevalence of metabolic syndrome and their associated risk factors amongst adults. Methodology: This was cross-sectional study piloted at the physiology department Bahawalpur Victoria Hospital, Bahawalpur for duration of one year from January 2018 to January 2019. All the information including socio-demographic and anthropometric information were recorded on a predesigned Performa. Blood samples were taken and sent to hospital laboratory for blood chemistry analysis. All of the data was analyzed by using the SPSS version 23 software. Results: In this study a total of 750 participants were included. The overall prevalence of metabolic syndrome was observed in 260 (34.67%) participants. In our study, 156 (60%) female participants and 104 (40%) male were observed with metabolic syndrome. Obese participants having OR of 15.77, age ≥51 years with OR 6.11 and overweight participants with OR of 6.55 were at high risk to develop metabolic syndrome in our study. Based on our study findings, the most common and important factors that affect participants were hyperglycemia (OR: 4.84), high blood pressure (OR: 4.31), abdominal obesity (OR: 350.55), high-TG (OR: 5.81) and low-HDL (OR: 10.3). Conclusion: Our study concludes that metabolic syndrome is high prevalent in our population with female predominance. Keywords: Prevalence; Metabolic syndrome; Risk factors; Adults
Prevalence and Severity of TMJDS among Undergraduates
Authors: Umar Shah Mohammad , Yousaf Usman , Ilyas Muhammad , Afzal Muhammad , Abbas Muhammad , Faheemuddin Muhammad , Tariq Amina
Published: March 2022

Objective: The purpose of study was to explore the prevalence of TMD and level of severity among undergraduate students. Method: This analytical crossectional study was conducted in Lahore. Data was collected from 406 undergraduate students using Fonseca's anamnestic index. After data collection, it was entered and analyzed in SPSS version 25. Frequencies and percentages were calculated as descriptive analysis and Chi-Square test was used to explore the difference between the prevalence of TMD according to severity in terms of gender and age. Results: 234 (57.6%) of the students didn’t have TMD while 172 (42.4%) reported TMD on the basis of questionnaire. Of the total 172 students who had TMD, 159 (92%) Mild TMD, 10 (6%) had Moderate TMD and only 3 (2%) had sever TMD. Conclusion: In undergraduate students almost half of the population had TMD whereas mild form of TMD was observed in majority of the undergraduate students. Keywords: Temporomandibular disorders, Fonseca's anamnestic index, undergraduate students, Severity of TMD