bluuebunny/crossref_metadata_2025 huggingface dataset:
Who May Geoengineer: Global Domination, Revolution, and Solar Radiation Management
Authors: Smith Patrick
Published: January 2022

This paper uses a novel account of non-ideal political action that can justify radical responses to severe climate injustice, including and especially deliberate attempts to engineer the climate system in order reflect sunlight into space and cooling the planet. In particular, it discusses the question of what those suffering from climate injustice may do in order to secure their fundamental rights and interests in the face of severe climate change impacts. Using the example of risky geoengineering strategies such as sulfate aerosol injections, I argue that peoples that are innocently subject to severely negative climate change impacts may have a special permission to engage in large-scale yet risky climate interventions to prevent them. Furthermore, this can be true even if those interventions wrongly harm innocent people.
Introduction
Authors: Heyward Clare , Lo Coco Laura
Published: January 2022

N/A
A Reply to My Critics
Authors: Armstrong Chris
Published: January 2022

It is a real pleasure to reply to so many thoughtful and probing responses to my book. In what follows, I will focus on six key themes that emerge across the various pieces. Some of them call into question core commitments of my theory, and in those cases I will try to show what might be said in its defence. Quite a number of the critics, however, present what we might call expansionist arguments: though they endorse some of the arguments I make, that is – or pick up some of its key concepts – they seek to push them in new and interesting directions. I will suggest that many of those arguments look likely to be successful, though I will also express caution about one or two of them. I doubt, however, that I will be the final judge of their success. Early on in the book I express the hope that it might provide a set of conceptual tools capable of advancing discussions about resource justice more broadly, even for scholars who reject my own idiosyncratic approach. Having made that gambit, I cannot now claim to have a monopoly on the use of the tools in question. Witnessing the use that others have already made of them has been a refreshing and rewarding experience.
Wenjiite, Ti10(Si,P,☐)7, and kangjinlaite, Ti11(Si,P)10, new minerals in the ternary Ti-P-Si system from the Luobusa ophiolite, Tibet, China
Authors: Xiong Fahui , Xu Xiangzhen , Mugnaioli Enrico , Gemmi Mauro , Wirth Richard , Yang Jingsui , Grew Edward S.
Published: January 2022

The new minerals wenjiite, Ti10(Si,P,☐)7 (IMA2019-107c) and kangjinlaite, Ti11(Si,P)10 (IMA2019-112b) occur with badengzhuite, zhiqinite, and a K-bearing dmisteinbergite-like mineral in a spheroid 20 μm across enclosed in corundum from the Cr-11 podiform chromitite orebody near the Kangjinla, Luobusa ophiolite, Tibet, China. In addition, wenjiite occurs with deltalumite, jingsuiite, osbornitekhambaraevite, and the K-bearing dmisteinbergite-like mineral in a lamellar intergrowth 100 μm long, also enclosed in corundum from the same locality. The new minerals were characterized by energy-dispersive spectroscopy and three-dimensional electron diffraction, which enabled us to obtain an ab initio structure solution and dynamical refinement from grains a few micrometers across hosted in a FIB lamella. Four analyses of wenjiite from the spheroid gave in wt% Si 21.67, P 6.24, Ti 66.39, V 1.37, Cr 2.20, Mn 0.97, and Fe 1.17 (normalized to 100), which corresponds to (Ti0.93Cr0.03Mn0.01Fe0.01V0.02)10 (Si0.79P0.21)6.51 on the basis of 10 cations excluding Si and P. The simplified formula is Ti10(Si,P)6.5, or more generally Ti10SixPy, where x > y and 6 ≤ (x + y) ≤ 7, i.e., Ti10(Si,P,☐)7. Wenjiite has hexagonal symmetry, space group: P63/mcm (no. 193), with a = 7.30(10) Å, c = 5.09(10) Å, V = 235(6) Å3, Z = 1, and is isostructural with xifengite, mavlyanovite, synthetic Ti5Si3, and synthetic Ti5P3.15. Four analyses of kangjinlaite gave in wt% Si 25.56, P 9.68, Ti 62.35, V 0.21, Cr 0.83, Mn 0.42, and Fe 0.95 (normalized to 100), which corresponds to (Ti10.65V0.03Cr0.13Mn0.06Fe0.14)Σ11.01(Si7.43P2.55)Σ9.99. The simplified formula is Ti11(Si,P)10. Kangjinlaite is tetragonal, with space group: I4/mmm (no. 139), a = 9.4(2) Å, c = 13.5(3) Å, V = 1210(50) Å3, Z = 4, and is isostructural with synthetic compounds of the Ho11Ge10 type, being the most compact of these phases. Despite there now being over 70 compounds containing 38 elements isostructural with Ho11Ge10, synthesis of an analog of kangjinlaite has not been previously reported in either the Ti-P or Ti-Si binary systems or in a multicomponent system. The previously deduced crystallization sequence with decreasing temperature of the four minerals in the spheroid is wenjiite → kangjinlaite → zhiqinite + badengzhuite. This sequence is consistent with relationships reported in 9 binary systems containing intermetallic compounds of Ge and Sn isostructural with Mn5Si3 and Ho11Ge10. In eight of these systems the Mn5Si3 analog melts congruently, whereas the Ho11Ge10 analog never does. Instead, the Ho11Ge10 analog melts peritectically, generally to an Mn5Si3 analog and less commonly to compounds with 5:4 stoichiometry. Final crystallization of the spheroid to zhiqinite + badengzhuite is expected to be well below the temperature of 1500 °C for the congruent melting of zhiqinite in the Ti-Si system, i.e., in the range of ~1100–1300 °C.
Color effects of Cu nanoparticles in Cu-bearing plagioclase feldspars
Authors: Jin Shiyun , Sun Ziyin , Palke Aaron C.
Published: January 2022

The optical properties (scattering, absorption, and extinction) of spheroidal Cu particles embedded in intermediate plagioclase feldspar are computed for various sizes and shapes using the Mie theory and T-matrix method. The observed color for Cu-bearing plagioclase, as a function of particle size and shape, is also calculated from the computed extinction spectra. The colors and pleochroism observed in natural and treated Cu-bearing plagioclase can be explained from the computational results. The enigmatic green colors in some precious Oregon sunstones result from red light being scattered away by Cu nanoparticles of certain sizes. The UV-VIS spectra are collected on Cu-bearing plagioclase samples for comparison with the computational results, which are shown to match the optical observations. The results from this work may be used to quantify the concentration of colloidal Cu in plagioclase or glass with a similar refractive index. Particle sizes and shapes can also be characterized using extinction and scattering spectra, which can be collected with different optical configurations. New materials with special color effects and optical characteristics may be designed and engineered by applying the unusual properties of metal colloids.
The Implementation of Short English Movie to Improve Students’ Vocabulary Mastery in Interpretive Listening Class
Authors: Tnomat Densiana , Billik Marthisa Oliva , Banu Tri Buce. J
Published: January 2022

This paper aims to investigate the students’ vocabulary mastery improvement after the implementation of a short English movie in Interpretive Listening class. There were 15 students of Interpretive Listening class of STKIP SoE as the participants. The researcher used Classroom Action Research as the method and collected the data by using test, in the form of pretest, posttest and observation for the students’ vocabulary mastery. The result of the study indicated that short English Movie can improve students’ vocabulary mastery. The improvement covered, the students’ being active in the process of teaching and learning in the classroom.
STRESS AND BURNOUT SYNDROME AMONG MOROCCAN MEDICAL STUDENTS: A CROSS-SECTIONAL STUDY
Authors:   Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir Morocco., Lahlou Laila , Benhamza Sabah ,   Faculty of Medicine and Pharmacy University Hassan2 Casablanca Morocco., Karim Nafissa ,   Faculty of dental medicine Casablanca Morocco., Obtel Majdouline ,   Laboratory of Epidemiology, Clinical Research, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat Morocco., Razine Rachid ,   Laboratory of Epidemiology, Clinical Research, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat Morocco.
Published: January 2022

Background:Christina Maslach and colleagues define burnout as a psychological syndrome in response to chronic interpersonal stressors on the job which is further characterized by its three dimensions of exhaustion, depersonalization, and a decreased sense of accomplishment. Burnout and stress are symptomatically similar, with burnout attributed specifically to occupational or academic stressors. Both can cause seriousconsequences on studenthealth, professionalism, and patient care. There are few studies evaluating the level of stress and burnoutsyndrome among medical students in Morocco.The aim of this study was to assess the prevalence and levels of burnout syndrome to identify associated factors as well as the level of stress among a group of medical students in Morocco. Method: Our study was descriptive andcross-sectional. It focused on 5th grade level medical students and was carried out during the month of November 2014. Data was collected through a self-administered questionnaire based on volunteering. Results:The study was conducted in a total of 178 fifth-year medical students. The response rate was 97.2% (n = 173). The mean age was 22.2 years (SD = 0.87 years) with a female predominance (74%). The average daily working hours were 8.33 hours (SD= 2.74) and the average daily hours of sleep was 7 hours (SD= 1.1). The majority of students (96.5%) were single.The prevalence of burnout, based on Maslach Burnout Inventory, was 49% (n = 87) of students.The prevalence of high emotional exhaustion was 44%, high depersonalization was 33.3% and high burnout score for personal accomplishment accounted for 64 %.We found a positive correlation between the number of working hours and the burnout score (r = 0.341, p <0.001) as well as the stress score (r=0.3, p=0.009). We also found a negative correlation between the number of hours of sleep and the Burnout score (r = -0.215, p = 0.019).Clearly, this study provides an idea for necessity to plan specific interventions to reduce student stress and avoid burnout.
A STUDY ON AIR POLLUTION TOLERANCE INDEX (APTI) AND ANTICIPATED PERFORMANCE INDEX (API) OF SOME PLANTS
Authors:   Dr.Shyama Prasad Mukherjee Govt Science and Commerce College Bhopal (M.P.) India., Singh Garg K. , Pal M. ,   Mittal Institute of Education Bhopal (M.P.) India., Jain Kirti ,   Dr.Shyama Prasad Mukherjee Govt Science and Commerce College Bhopal (M.P.) India.
Published: January 2022

Due to industrialization, urbanization and increasing number of vehicles air pollution has turn out to be serious problem today. Now a days particulate matter shows the undesirable effects on plants, animals and human beings also. Tree plantation programme is the best ways to control the air pollution. Most of the plants filter the air by their aerial elements. Vegetation naturally cleanses the atmosphere by absorbing gases and some particulate matters through leaves so they work as sink for air pollution and reduce pollution level in atmosphere. Leaves function as an efficient pollutant trapping device. Air pollution can directly affects plants via leaves or indirectly via soil acidification. Air pollution tolerance index (APTI) is an intrinsic quality of trees to control air pollution problems. The trees higher tolerance index are tolerance towards air pollution and can be used a source to control air pollution. Air pollution tolerance index can be used as an indicator of rate of air pollution. By combining biochemical and aggregate factors the anticipated performance index (API) is prepared which is used as development of green belt. Thus, the assessment of APTI and API potential of different trees are used to control air pollution.
THE PREVALENCE AND RISK FACTORS FOR HYPERBILIRUBINEMIA IN NEONATES
Authors:   Lecturer, Lisie College Of Nursing, Ernakulam., Maria Joy Grace , Mony K. Sr. ,   Principal, PIMS, College Of Nursing, Pondichery.
Published: January 2022

Background: Jaundice is very common in the neonatal period of life especially hyperbilirubinemia>12 mg/dl. Although it is not a major cause of mortality, it is an important cause of morbidity. So, assessment of the prevalence and risk factors of neonatal jaundice is very important. Objectives: The objectives of the study were to estimate the prevalence,to identify the risk factors and to findout the association between hyperbilirubinemia with selected neonatal,maternal,environmental and socio demographic variablesand to identify the risk factors. Methodology: This descriptive cross sectional survey study was conducted among 200 neonates of 37 completed weeks of gestation. Subjects were selected by using total enumerative sampling.Transcutaneous bilirubin was measured by bilirubinometer,clinical and demographic variables collected by using semi structured questionnaire and the risk factors were assessed by interview schedule. Results:Research showed that most of neonates (81.5%) had Transcutaneous bilirubin level more than 12mg/dl, out of that (15% )subjects had elevated level of bilirubin 15- 20mg/dl. It is concluded that there is high prevalence of hyperbilirubinemia among neonates . It is evident that neonates developed hyperbilirubinemia by 48 to 72 hours. It is inferred that prevalence of hyperbilirubinemia was high at 72 hours (56.5%) after birth compared to 48 hours of birth (38%). There was a significant association between level of hyperbilirubinemia and family history of genetic diseases (P=0.003),parity (p=0.03, Ï‡2=4.37),mode of conception(p=0.012, Ï‡2=6.37), and gestational age(P=0.04),gender of the neonate (p=0.004, Ï‡2=8.1)and duration of second stage of labour (p=0.026, Ï‡2=7.27). The study revealed that the family history of genetic diseases (p=0.004),(OR=0.09) at level of significance 0.05,is a risk factor leads to hyperbilirubinemia. Conclusion: Neonatal jaundice is a leading cause of hospitalisation in the first few weeks of life throughout the world.Though major complications may arise like kernicterus,encephalopathy and neural sequlae.Hence there is an exigent need for assessing the bilirubin value in the routine neonatal assessment.
MODELING AND PREDICTING THE MONO RIVER OVERFLOW UPSTREAM OF THE NANGBETO DAM IN WEST AFRICA USING MULTIPLICATIVE DETERMINIST MODEL
Authors:   Laboratory of Energetics and Applied Mechanics, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin., Bacharou Taofic ,   Laboratory of Applied Ecology, Faculty of Agronomic Sciences, University of Abomey-Calavi. BP 526 Cotonou, Benin., Prodjinonto Vincent ,   Laboratory of Energetics and Applied Mechanics, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin., Agossa Linsoussi Come ,   Laboratory of AppliedHydrology, PolytechnicSchool of Abomey-Calavi, 01 BP: 526 INE/UAC, Cotonou, Benin.
Published: January 2022

The variation and non-control of the overflow of the Mono River adversely affects the performance of the Nangbetohydropower plant to the point thatitcan no longermeet the increasinglyincreaseddemand for electricity. This studypresents the development of an operational model for forecastingdaily river flows for the plants water retention. The overflow of the Mono River at the upstreamhydroelectric dam from 1991 to 2019 wasanalyzed and modeled by the deterministicprocesswith R software in order to makepredictions. First, the flow serieswasanalyzed by the ARIMA model (18, 1, 2) then by a multiplicative model afterremoving the seasonal trends fromtheseseries by the movingaveragemethod. The calculatederror of the results of said model revealsthat the deterministic model integrates the input generationprocesseswith an error of the order of . Finally, an annual flow forecasting program has been developed as a planning tool for the operation of the dam, in order to meet production needs and to plan water releases.
INFECTED MECKELS DIVERTICULUM MASQUERADING AS SPONTANEOUS RUPTURE OF UMBILICAL GRANULOMA - A CASE REPORT IN ONE MONTH OLD INFANT
Authors:   Consultant, Department of Pediatric Surgery, Konaseema Institute of Medical Science and Research Foundation, Chaitanya Nagar, Amalapuram, Andhra Pradesh, India., Karthik Garikaparti Naga , Nimmala Pavankumar ,   Consultant, Department of Surgery, Dr. Seshaiah PrajaVaidyasala Hospital, Andhra Pradesh, India., Kamala Priya Tata ,   Postgraduate Student, Department of Surgery, Konaseema Institute of Medical Science and Research Foundation, Chaitanya Nagar, Amalapuram, Andhra Pradesh, India., Jahnavi Dharmapuri ,   House Surgeon, Department of Surgery, Konaseema Institute of Medical Science and Research Foundation, Chaitanya Nagar, Amalapuram, Andhra Pradesh, India.
Published: January 2022

Meckels Diverticulum can present as umbilical cord infection which mimicking an umblical granuloma. A 1 month, old infant had presented with herniated bowel loops, following an ultrasound procedure. The purpose of the report is to highlight on variable presentation of Meckels Diverticulum in a suspected case of umblical granuloma.
BOOST CUSTOMER LOYALTY DURING PANDEMIC COVID 19 THROUGH PHYSICAL ENVIRONMENT AND INTERACTION WITH STAFF AND CUSTOMER IN LOCAL AMUSEMENT PARK MALANG INDONESIA
Authors:   Pelita Harapan University, Lippo Village Campus., Tatimu Erric , a Ronald ,   Pelita Harapan University, Surabaya Campus., b Amelia ,   Pelita Harapan University, Surabaya Campus.
Published: January 2022

According to Undang-Undang (UU) No. 25 of 1992, a Tourism continues to develop not only in developed countries, but also in developing countries like Indonesia. Indonesia itself has many tourist cities, one of which is famous and even recognized for its beauty by foreigners is the city of Malang. One of the attractions in the city of Malang is Malang Night Paradise. Malang Night Paradise has a lantern park rides that will have an atmosphere like being in a fairyland with extraordinary beauty at night. In the midst of increasingly fierce tourist attractions in Malang and surrounding areas, it is important for Malang Night Paradise to always increase customer loyalty from Malang Night Paradise customers. In this study respondents collected were 200 visitors Malang Night Paradise in Surabaya according to the characteristics of respondents using snowball technique. Based on data analysis is that from nine proposed hypotheses, eight hypotheses are supported and one hypothesis is rejected.
LEFT VENTRICULAR (LV) CLOT IN PATIENTS WITH ST ELEVATION MYOCARDIAL INFARCTION
Authors:   DrNB Cardiology, SSH, GMC Jammu., Ahmed Wani Owais , Ali Nasir ,   Consultant Cardiology, SSH, GMC Jammu., Qayoom Ouber ,   DrNB Cardiology, SSH, GMC Jammu., Beniwal Rajveer ,   DrNB Cardiology, SSH, GMC Jammu.
Published: January 2022

CAD is the leading cause of death throughout the world. Regarding the complication of myocardial infarction, the left ventricular thrombus (LVT) formation is of greater concern. Once the LVT is formed, it possesses increase potential to embolise systemically and may complicate a serious life- threatening condition i.e. stroke. Objective:To find out the frequency of LV clots in patients presenting with myocardial infarction. Method: Diagnosed MI patients were included in this study based on a convenient sampling technique. The data was collected through a standard pro forma and was analyzed through SPSS . The P-value was calculated to determine the significance of the result. Results: Out of 168 patients with MI, 118 (70.2%) were males and 50 (29.8%) were females. The mean age was 55.46Â± 9.54 years. On Echo, 17 (10%) patients had LVT, of which 10 cases were from male gender and seven from females. The frequency of LVT was higher in anterior MI in 16 out of 17 LVT cases (94.1%), and in other types of MI, the frequency was lower, 1 case out of 17 cases (5.9%). The frequency of LVT was also higher in the age group >50 years (70%) and was lower in the age group <50 years (30%). Conclusion: LV clot is a common complication after MI, and the frequency of LVT is more common in the age group greater than fifty and associated more with anterior MI.
HEAT TRANSFER ENHANCEMENT USING HELICAL PIPES
Authors:   Specialist Trainer B , High Institute of Energy, Kuwait., Abdulhadi Ethbayah Waleed
Published: January 2022

The enhancement of laminar forced convection inside helical pipes is studied numerically and compared with plain pipes. The study is achieved numerically using the (Fluent-CFD 6.3.26) software program for solving the governing equations. The heat transfer factor and friction factor are calculated using the enhancement technique and compared with the plain tube. In this research the factors that affect the enhancement technique using helical pipes are studied, these factors are the ratio of (pitch /pipe length) (SL), Reynolds number and the heat flux applied to the external surface of the pipe. The results showed that there is an increasing in the heat transfer factor is related to the decreasing of (SL), increasing of Reynolds number and heat flux. The performance of the helical pipes is evaluated depending on the calculation of (Enhancement ratio), and its found that the enhancement ratio increases as Reynolds number increases and (SL) decreases. It is found that the best enhancement ratio was (200%) at (SR=0.05), (Re=2000),(Heat flux=3000W/m2).The results are compared with the literature and there is a good agreement.
CLINICAL PROFILES OF PATIENTS UNDERGOING PACEMAKER IMPLANTATION
Authors:   DrNB Cardiology, SSH, GMC Jammu., Ahmed Wani Owais , Ali Nasir ,   Consultant Cardiology, SSH, GMC Jammu., Qayoom Ouber ,   DrNB Cardiology, SSH, GMC Jammu., Beniwal Rajveer ,   DrNB Cardiology, SSH, GMC Jammu.
Published: January 2022

Background and Objective: The implantation of a permanent cardiac pacemaker for the treatment of bradyarrhythmia is one of the most popular cardiac interventions. The goal of this study is to look at the clinical profiles of individuals who have permanent pacemakers implanted Material and Methods: The study was conducted using observational methods. The study included patients who received a permanent pacemaker for bradyarrhythmias between November 2019 and November 2021. A thorough review of the demographic profile and indications was performed. Results: The vast majority of the 312 patients were older, with the majority being between the ages of 56 and 88 years old (75 % ). Pacemakers were implanted in more men than in women. Complete heart block was the most common ECG finding and the most common presenting symptom was syncope. The most prevalent sign of pacing was acquired A-V block, and the most common pacemaker mode was single chamber (VVI/VVIR). Conclusion: Acquired A-V block and SSS were found to be the most common reasons for pacemaker implantation in our study. Higher implantation rates were linked to advanced age and male gender.
AN EMPIRICAL EVIDENCE OF ECONOMIC RECOVERY DURING THE PANDEMIC PERIOD INTO WORLD ECONOMY
Authors:   Assistant Professor Department of Business Administration University of Western Macedonia Greece., Kontsas Stamatis , Kalogiannidis Stavros ,   Adjunct Lecturer Department of Business Administration University of Western Macedonia Greece.
Published: January 2022

We are in the midst of an asymmetrical recovery. In some countries, COVID-19 infection rates have fallen significantly, while in others, the virus remains difficult to control. But whether governments are actively managing outbreaks or returning to normality, economic recovery is central to their forward-looking agenda without a broad-based economic expansion, it is difficult to address other challenges, such as education and healthcare.The International Monetary Fund(IMF) recently raised its projection for economic growth in 2021 to 6%, up from 5.5%, and projects 4.4% growth in 2022. The upgraded outlook is based on how well the pandemic continues to be controlled, the efficacy of fiscal policy in mitigating economic damage and global financial conditions. Although businesses are the engines of the economy, governments create the environment and structure that enable enterprise to flourish . How governments create and shape the environment for economic recoveryâ€”and the opportunities and challenges they face in doing soâ€”will depend on two decisions they make about their approach.
HISTOMORPHOLOGICAL FINDINGS AND CLINICO-RADIOLOGICAL CORRELATION OF INTESTINAL ATRESIA AT A TERTIARY CARE CENTRE
Authors:   Senior Resident, Department of Pathology, IGIMS, Patna., Sunita Bharati Kumari , Kumar Singh Sanjeet ,   Additional Professor, Department of Pathology, IGIMS, Patna., Chandra Kalpana ,   Assistant Professor, Department of Pathology, IGIMS, Patna., Hasan Zaheer ,   Additional Professor, MCH, Department Pediatric Surgery, IGIMS, Patna., Prasad Umakant ,   Associate Professor, Department of Radiology, IGIMS, Patna.
Published: January 2022

Background: An atresia is a congenital defect of a hollow viscus that results in complete obstruction of the lumen. Intestinal atresia is one of the most frequent causes of bowel obstruction in the newborn and can occur at any point in the gastrointestinal tract. This study was undertaken to study the histomorphological findings of intestinal atresia and to correlate it with different subtypes and clinico-radiological feature. Material and methods: This was a prospective observational study conducted in 24 months on the resected gastrointestinal tract of 40 neonatal intestinal obstruction cases admitted in Pediatric surgery ward received in the Department of Pathology, Indira Gandhi Institute of Medical Sciences, Patna. Control Group- A total of 5 cases of vitello-intestinal duct patency were taken as control and compared with the study group. Results: With respect to total 40 cases, there were six, i.e. 15.0% female babies and 34, i.e. 85.0% male babies studied. Out of that, 15 i.e. 37.50% were full term and 25, i.e. 62.5% were premature. Mucosa showed oedema, ulceration and flattening in 9 cases. Apart from flattening and oedema, mucosa was denuded at some places and also showed congestion and extravasated blood in 6 cases each. Abnormal villus configuration, calcium deposition in 4 cases each and hypertrophied mucosa were found in 3 cases. Luminal narrowing, loss of mucosa, duplication of mucosa and gangrenewere found in one case each. Sub mucosal changes showed congestion in 33 cases, oedema in 15, Fibrosis in 4, thickened submucosa in 2 cases and dilated irregular branching blood vessels, extravasted blood, calcification in 1 case each. Muscularispropria having changes i.e. thinning in 16 cases, congestion, hypertrophy in 4 cases each, focal loss in 3 cases, calcification in 2 cases and thinning in 2 cases. Similarly, histopathological changes in serosa shows serositis in 16 cases, congestion in 11 cases and thinning in 3 cases. Oedema and congestion were present in 2 cases, hypertrophy and calcification in 1 case each. Conclusion:In this study spectrum of histomorphological changes in the atretic segment has been described. Histomorphological changes at atretic segment can be valuable to surgeons in deciding the type of surgery and minimizing the postoperative intestinal dysmotility, which remains the most common complication of intestinal atresia.
STUDY OF SELF-SUPERPOSABLE FLUID MOTIONS IN CONFOCAL PARABOLOIDAL DUCTS
Authors: Mishra Rajeev
Published: January 2022

In this paper, studies have been made on some self-superposable motion of incompressible fluid is confocal Paraboloidal ducts. The boundary conditions have been neglected therefore the solutions contain a set of constants. Pressure distribution and the nature of vorticity are discussed. Tendency of irrotationality of the fluid flow is also determined. The aim of the paper is to introduce a method for solving the basic equations of fluid dynamics in confocal paraboloidal coordinates by using the property of self superposability.
ANNELERİ İLE CEZA İNFAZ KURUMLARINDA KALAN 0-3 YAŞ ÇOCUKLARININ BAĞLANMA SÜREÇLERİNİN DESTEKLENMESİ VE SAĞLIKLI GELİŞİMLERİ İÇİN BİR PİLOT ÇALIŞMA: DUYGU SALINCAĞI
Authors: KARADENİZ Gülçin , ZABCI Neslihan , GEZGİN Sinem , KATİP Ceren
Published: January 2022

Önleyici/müdahale edici ya da destekleyici projeler üretmek, sosyal politikalar geliştirilmesi açısından önem taşımaktadır. Kadın kapalı ceza infaz kurumunda annesi ile kalan çocuklar için geliştirilen bu önleyici projenin amacı; 0-3 yaş arası çocukların tüm gelişim alanlarını annelere verilecek eğitim ile birlikte desteklemek, anne ve çocuk arasındaki duygusal bağı güçlendirmek ve etkileşimi arttırmaktır. Proje çalışmasının diğer bir amacı da çocuklar için kullanılan oyun alanını geliştirmek ve düzenli kullanılmasını sağlamaktır. Bu noktalardan hareketle gelişimsel değerlendirmeler yapılmış ve ihtiyacı olan çocuklara sağlanan bireysel psikoterapi sürecinin ruhsal gelişimi nasıl etkilediği incelenmiştir. Çalışma kapsamında, 0-3 yaş grubu 31 çocuk ve anneleri ile çalışılmıştır. Bu doğrultuda eğitim öncesi ve sonrasında annelere; Demografik bilgi formu, Ebeveyn-Çocuk Kapsayıcı İşlevler Ölçeği, ACE Travma Ölçeği, Çocukluk Çağı Travmaları Soru Listesi, Marschack Etkileşim Değerlendirmesi uygulanmıştır. Çocuklara ise proje başlangıç ve bitiminde; AGTE Gelişim Testi, 1-3 Yaş Sosyal Duygusal Değerlendirme Ölçeği kullanılmıştır. Araştırma sonucunda ön test ve son test ölçümleri arasında anlamlı farklar olduğu görülmektedir.
DISSENTING OPINION IN THE CONSTITUTIONAL JUSTICE AND THE EVOLUTION OF LEGAL SCIENCE
Authors: KARPENKO Konstantin V.
Published: January 2022

The article deals with the influence of the dissenting opinions of constitutional judges on the development of legal science. This issue is usually very important for constitutional and legal science as its understanding and practical resolution influence the authority of constitutional justice in a state. The dissenting opinion of any judge is their right to express their reasoned disapproval of the rendered decision, formulated in writing and attached to the court decision. Dissenting opinions in constitutional proceedings are of increased importance, because decisions of constitutional courts are aimed to protect law and order in general and are addressed to entire population.
The dissenting opinions of constitutional judges contribute to the development of legal science in two aspects. On the one hand, they can contain new ideas, theories and approaches to law, with the help of which new categories and concepts are introduced into scientific discussion. On the other hand, dissenting opinions make often wide references to foreign experience in resolving legal conflicts. In this case, dissenting opinions fit into the framework of comparative legal research and allow taking into account the judicial practice and judicial argumentation of other countries and legal systems. Both aspects contribute to the expansion of the doctrinal base of legal science, pose and solve new problems, increase the need for scientific discussion.
This study is based on a formal-dogmatic scientific method, which is aimed at disclosing the true meaning of legal positions of judges presented in dissenting opinions. A systematic method is also used, which allows to identify and classify single areas of scientific knowledge. The author also applies the comparative legal method, which consists in comparing different legal positions in the dissenting opinions of judges.
The novelty of the research is in determination of contribution of dissenting opinions of constitutional judges to the development of legal science.
Determination of Both TP53 Mutation Status and the Amount of p53
Protein has Limited Diagnostic Importance for Patients with Ovarian
Cancer
Authors: Klein Sebastian M. , Bozko Maria , Toennießen Astrid , Malek Nisar P. , Bozko Przemyslaw
Published: January 2022

Background:

Ovarian cancer is one of the most aggressive types of gynecologic cancers. Many patients have a relapse within two years after diagnosis and subsequent therapy. Among different genetic changes generally believed to be important for the development of cancer, TP53 is the most common mutation in the case of ovarian tumors.

Objective:

Our work aims to compare the outcomes of different comparisons based on the overall survival of ovarian cancer patients, determination of TP53 status, and amount of p53 protein in tumor tissues.

Methods:

We analyzed and compared a collective of 436 ovarian patient’s data. Extracted data include TP53 mutation status, p53 protein level, and information on the overall survival. Values for p53 protein level in dependence of TP53 mutation status were compared using the Independent-Samples t-Test. Survival analyses were displayed by Kaplan-Meier plots, using the log-rank test to check for statistical significance.

Results:

We have not found any statistically significant correlations between determination of TP53 status, amount of p53 protein in tumor tissues, and overall survival of ovarian cancer patients.

Conclusion:

In ovarian tumors both determination of TP53 status as well as p53 protein amount has only limited diagnostic importance.
Recent Advances in Dimethyl Sulfoxide (DMSO) Used as a Multipurpose Reactant
Authors: Cai Su-Qian , Zhang Ke-Feng , Cai Xiao-Hua
Published: January 2022

Dimethyl sulfoxide (DMSO) is not only a common and cheap aprotic polar solvent
with low toxicity but also serves as an efficient and multipurpose reactant, and has widely
been used in organic synthesis. DMSO as an important precursor can effectively introduce a
broad range of functional fragments into organic molecules, such as -Me, -CH, -CH2, -SMe2, -
CH2SMe, -CH2SOMe, -SMe, -SO2Me, -SOMe or O substituents, and serves as a mild oxidant
in organic transformations. Many significant achievements based on DMSO as a synthon in
synthetic chemistry have rapidly been made over the past several years. To help researchers
further understand the recent advances in the field, the review summarizes the applications of
DMSO as carbon, sulfur, and oxygen sources and its use as the dual synthon in synthetic
transformations.
Aptamers Against COVID-19: An Untested Opportunity
Authors: Haberland Annekathrin , Müller Johannes
Published: January 2022

Given the lack of success in the development of effective drugs to treat COVID-19, which show “game-changing” potential, it is necessary to explore drugs with different modes of action. Single mode-of-action drugs have not been succeeded in curing COVID-19, which is a highly complex disease. This is the case for direct antivirals and anti-inflammatory drugs, both of which treat different phases of the disease. Aptamers are molecules that deliver different modes of action, allowing their effects to be bundled, which, when combined, support their therapeutic efficacy. In this minireview, we summarise the current activities in the development of aptamers for the treatment of COVID-19 and long-COVID. A special emphasis is placed on the capability of their multiple modes of action, which is a promising approach for treating complex diseases such as COVID-19.
Development of an Insulin Nano-delivery System through Buccal Administration
Authors: Bozeya Ayat , Al-Domi Diaa , Al-Fandi Mohamed
Published: January 2022

Aim:

The aim of the study was to develop a new nano-delivery system for buccal administration
of insulin.

Background:

Biodegradable polymeric nanoparticles (PNPs) had undergone countless breakthroughs
in drug delivery systems. The main objective of PNPs application in delivering and carrying
different promising drugs is to make sure that the drugs are being delivered to their action sites,
maximizing the desired effect and overcoming their limitations and drawbacks.

Objectives:

The main goals of this study were to produce an insulin consumable nano-delivery system
for buccal administration and enhance the mucoadhesive effect in sustaining insulin release.

Methods:

Water-oil-water (W-O-W) microemulsion solvent evaporation technique was used for
the preparation of nanoparticles consisting of positively charged poly (D, L-lactide-co-glycolide)
coated with chitosan and loaded with insulin. Later, a consumable buccal film was prepared by the
spin coating method and loaded with the previously prepared nanoparticles.

Results:

The newly prepared nanoparticle was assessed in terms of size, charge and surface morphology
using a Scanning Electron Microscope (SEM), zeta potential, Atomic Force Microscope
(AFM), and Fourier Transform Infra-red (FTIR) spectroscopy. An in-vitro investigation of the insulin
release from nanoparticles and buccal film demonstrated controlled as well as sustained delivery
over 6 hrs. The cumulative insulin release decreased to about 28.9% with buccal film compared
to the nanoparticle (50%).

Conclusion:

The buccal film acted as a barrier for insulin release. Therefore, the release was sustained.
Green and Efficient Synthesis of 1, 2, 4-Triazolidine-3-thiones using
Guanidine Hydrochloride as a Recyclable Catalyst under the Aqueous
Condition
Authors: Barkule Angad B. , Gadkari Yatin U. , Telvekar Vikas N.
Published: January 2022

A rapid and highly efficient methodology for the synthesis of 1, 2, 4-triazolidine-3-thiones
derivatives has been developed in the presence of a catalytic amount of guanidine hydrochloride using
water as a solvent. The reaction of thiosemicarbazide with different aryl aldehydes resulted in the formation
of title compounds in good yields (85-95%) with a convenient reaction time (20-30 min). The
key advantages of this approach include shorter reaction time, energy efficiency, easy work-up procedure,
and wide substrate scope tolerance. Furthermore, the catalyst was recycled without significant
loss of its catalytic activity.
Genitourinary Tract Tumors in Children: An Update
Authors: García-Perdomo Herney Andrés , González-Arboleda Andrés Augusto , Fernandez Nicolás
Published: January 2022

Background:

Genitourinary tract tumors in children are less common than in adults.
Most of these tumors have different genetic backgrounds, clinical presentation, and oncologic behavior
than their adult counterpart. As a result of low prevalence in children, some of the treatment
approaches and recommendations are based on treatment experience in adult patients. However,
thanks to scientific and technological development, survival rates have risen considerably.

Objective:

This paper presents a review of the principal features of the tumors involving the genitourinary
tract in children and an update in genetic background, diagnosis, and treatment.

Methods:

A narrative review was performed on published literature about genitourinary tract tumors
in pediatric patients. Papers presented in English and Spanish literature were reviewed.
PubMed, Science Direct, and SciELO databases were used to collect information and present this
article.

Results:

Kidney tumors are the most common type of genitourinary tumors in children. Among
those, Wilms tumor represents the majority of cases and shows the successful work of clinical trial
groups studying this tumor type. Other tumors involving the genitourinary tract in children include
Rhabdomyosarcoma, Transitional cell carcinoma, Testicular, and Adrenal tumors.

Conclusion:

Genitourinary tract tumors in children represent significant morbidity and economic
burden, so awareness in early diagnosis represents improvement in treatment, clinical, and oncological
outcomes.
Impact of the COVID-19 Pandemic on Chronic Neurological Disorders: Focus on Patients with Dementia
Authors: Irrera Natasha , Barbieri Maria Antonietta , Bagnato Gianluca , Ioppolo Carmelo , Versace Antonio Giovanni
Published: January 2022

The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) represents a public health problem worldwide. COVID-19 triggers a maladaptive cytokine release commonly referred to as cytokine storm syndrome with increased production of proinflammatory cytokines, which also appears to contribute to chronic neuroinflammation and neurodegenerative disorders’ appearance, including multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease. In this context, SARS-CoV-2 might enter the central nervous system through binding with the angiotensin converting enzyme 2 receptors which are highly expressed in glial cells and neurons. For this reason, an association between COVID-19, its dependent cytokine storm, and the development and/or progression of neurodegenerative disorders might be evaluated. Therefore, the aim of this review was to assess the impact of COVID-19 on neurodegenerative disorders, focusing on the possible increased mortality risk and/or deterioration of the clinical course of pre-existing chronic neurological diseases in patients with dementia.
DFT Studies and Quantum Chemical Calculations of Benzoyl
Thiourea Derivatives Linked to Morpholine and Piperidine for the
Evaluation of Antifungal Activity
Authors: Tigote Radhakrishnan M. , Dongare Rameshwar K. , Inamdar Shaukatali N.
Published: January 2022

Background:

Benzoyl thiourea derivatives linked to morpholine and piperidine
have been reported to possess good antifungal activity.

Objective:

The aim of the study was to find the correlations between the quantum chemical
calculations and the antifungal activity of the benzoyl thiourea derivatives linked to morpholine
and piperidine.

Methods:

Optimization of six compounds BTP 1-3 and BTM 4-6 was carried out with DFT
using B3LYP method utilizing 6-31G(d,p) basis set. The structural parameters of the compounds
as molecular geometry, bond lengths, bond angles, atomic charges and HOMOLUMO
energy gap have been investigated and compared with the reported experimental results.

Results:

A good correlation between the quantum chemical calculations and the antifungal
activity of the benzoyl thiourea derivatives linked to morpholine and piperidine was found.

Conclusion:

The DFT study of benzoyl thiourea derivatives linked to morpholine and piperidine
conducted with respect to their Quantum chemical parameters for evaluation of
their antifungal activity showed good correlations between the antifungal activity and the
quantum chemical parameters.
Polymer Supported Proline-Based Organocatalysts in Asymmetric Aldol
Reactions: A Review
Authors: Saithalavi Anas , Shajahan Rubina , Sarang Rithwik
Published: January 2022

The use of proline-based organocatalysts has acquired significant attention in organic
synthesis, especially in enantioselective synthesis. Proline and its derivatives are proven to be quite
effective chiral organocatalysts for a variety of transformations, including the aldol reaction, which
is considered as one of the important C-C bond forming reactions in organic synthesis. The use of
chiral organocatalysts has several advantages over its metal-mediated analogues. Subsequently, a
large number of highly efficient proline-based organocatalysts, including polymer-supported chiral
analogues, have been identified for aldol reaction. The use of polymer-supported organocatalysts
exhibited remarkable stability under the reaction conditions and offered the best results, particularly
in terms of its recyclability and reusability. These potential benefits along with their economic
and green chemistry advantages have led to the search for many polymer-supported proline catalysts.
In this review, recent developments in exploring various polymer immobilized proline-
based chiral organocatalysts for asymmetric aldol reactions are described.
Оптические свойства сегнетоэлектрических пленок Hf-=SUB=-x-=/SUB=-Zr-=SUB=-y-=/SUB=-O-=SUB=-2-=/SUB=- и La : Hf-=SUB=-x-=/SUB=-Zr-=SUB=-y-=/SUB=-O-=SUB=-2-=/SUB=- по данным эллипсометрии
Authors: Кручинин В.Н. , Спесивцев Е.В. , Рыхлицкий С.В. , Гриценко В.А. , Mehmood F. , Mikolajick T. , Schroeder U.
Published: January 2022

В последнее время обнаружено наличие сегнетоэлектрических свойств наноразмерных пленок на основе оксида гафния. Такие пленки представляют большой интерес для разработки универсальной памяти, которая сочетает преимущества оперативной и флэш-памяти. В работе изучаются оптические свойства пленок оксида гафния-циркония HfxZryO2 и пленок оксида гафния-циркония, легированных лантаном, La : HfxZryO2. Флуктуации толщины пленок HfxZryO2 не превышают 3.5%, флуктуации толщины пленок La : HfxZryO2 --- 3.2%. Оптические свойства анализируются на основе теории эффективной среды. По данным теории эффективной среды пленки HfxZryO2 содержат 46% HfO2, 54% ZrO2, пленки La : HfxZryO2 содержат 47.5% HfO2, 52.4% ZrO2, 2.5% La2O3. Ключевые слова: сегнетоэлектрик, показатель преломления, спектроэллипсометрия, теория эффективной среды.
Small Practices, Big (QI) Dreams: Customizing Quality Improvement (QI) Efforts for Under-Resourced Primary Care Practices to Improve Diabetes Disparities
Authors: Lim Sahnah , Islam Nadia S
Published: January 2022

International Registered Report Identifier (IRRID)

RR2-10.1186/s13063-019-3711-y
COVID-19 Assessment and Testing in Rural Communities During the Pandemic: Cross-sectional Analysis
Authors: Fitzsimon Jonathan , Gervais Oliver , Lanos Chelsea
Published: January 2022

Background

The COVID-19 pandemic exacerbated the need for urgent improvements in access to health care for rural, remote, and underserviced communities. The Renfrew County Virtual Triage and Assessment Centre (VTAC) was designed to provide access to COVID-19 testing and assessment with a family physician. The goal was to protect emergency departments and 911 paramedics while ensuring that nobody was left at home, suffering in silence. Residents were encouraged to call their own family physician for any urgent health needs. If they did not have a family physician or could not access their usual primary care provider, then they could call VTAC. This study reports on the output of a service model offering access to assessment and COVID-19 testing through a blend of virtual and in-person care options by a multidisciplinary team.

Objective

The purpose of this study was to assess the ability of VTAC to provide access to COVID-19 assessment and testing across rural, remote, and underserviced communities.

Methods

We conducted a cross-sectional analysis of the data derived from the cases handled by VTAC between March 27, 2020 (launch day), and September 30, 2020.

Results

Residents from all 19 census subdivisions and municipalities of Renfrew County accessed VTAC. A total of 10,086 family physician assessments were completed (average 64 per day). Of these, 8535 (84.6%) assessments were to unique patient users. Thirty physicians provided care. Using digital equipment setup in the patients’ home, 31 patients were monitored remotely. VTAC community paramedics completed 14,378 COVID-19 tests and 3875 home visits.

Conclusions

Renfrew County’s experience suggests that there is tremendous synergy between family physicians and community paramedics in providing access to COVID-19 assessment and COVID-19 testing. The blended model of virtual and in-person care is well suited to provide improved access to other aspects of health care post pandemic, particularly for patients without a family physician.