bluuebunny/crossref_metadata_2025 huggingface dataset:
From Fenye to Latitude and Longitude: The Adjustment and Renewal of the Positioning System in Chinese Local Gazetteers during Qing Dynasty
Authors: Zhang Jiajing
Published: June 2024

Influenced by a cosmological view of the interconnectedness between heaven and humankind, ancient Chinese astrologers developed the fenye (分野, “field allocation”) system. This theory envisioned correspondence between heaven and earth and was a prevalent regional positioning system in ancient China. However, during the Qianlong era (1736-1796), fenye theory faced skepticism and rejection from official quarters, leading to a significant crisis for this traditional positioning system. With the eastward spread of Western learning, modern European astronomical and geographical knowledge were introduced into China, and Chinese intellectuals began to favor the Western system of latitude and longitude for geographical positioning. In the late Qing period, the gradual popularization of the spherical Earth concept and the latitude and longitude system laid the theoretical foundation for establishing of this system. The public dissemination of latitude and longitude data measured by the imperial astronomical and calendrical institutions, along with mathematicians’ calculations based on historical data and the supplementary measurements conducted by local governments, provided data support for the system’s establishment. By the end of the Qing dynasty, as the knowledge structures and worldviews of Chinese intellectuals transformed, the traditional celestial-terrestrial correspondence in Chinese local gazetteers was phased out, giving way to the latitude and longitude system.
From the “dirty port” to the Disinfection Service of the Port of Rio de Janeiro (1893-1911)
Authors: Mantuano Thiago
Published: June 2024

This article demonstrates how sanitation was one of the many issues that led to the heavy opposition to the operation of the Port of Rio de Janeiro, at the end of the nineteenth century. Aside from the historiographical framework that centers on the movement of people and objects through ports as a threat to public health at that time, the aim was to clarify how the port itself and its infrastructures were considered hazardous and unsanitary and how the sanitation defense procedures were found to be inadequate and ineffective. The evidence presented here points to the destruction-construction of the Port of Rio de Janeiro, in the early twentieth century, as a solution to radically transform its infrastructure. The port under construction was consonant with the full technical-technological implementation of the “disinfection” service, which both supported its new operation and helped solve the public health issues afflicting the city.
Proximate Composition and Antioxidant Activity of Honey Bee Collected Pollen in the Main Flowering Season, in West Shewa Zone, Central Ethiopia
Authors: Yadeta Gemechis L. , Degaga Emana G. , Merti Admassu A.
Published: June 2024

This study aimed to assess the effect of botanical and geographical differences on the protein, minerals, total phenolic content and the antioxidant activity of bee pollen collected from five districts in West Shewa Zone, Ethiopia. Pollens of Guizotia sp., Brassica sp., Trifolium sp., Eucalyptus sp., Plantago lanceolata and Vicia faba were color-sorted from multifloral pollens and subjected to chemical analysis. The results revealed the mean content of moisture 10.6% of fresh weight (FW), protein 19.4% of dry weight (DW) and ash 2.4% (DW); the most dominant minerals, K (9765.6), Ca (963.4), Mg (960.5), Fe (142.8) and P (126.5) in mg/kg DW. The average of the total phenolic content (TPC) and the antioxidant activity (DPPH radical) were 40.3 GAE mg/g FW and 13.7 AAE mg/g FW (gallic and ascorbic acid equivalent, respectively). V. faba pollen had the highest protein, ash, P and Cu content. Four pollen taxa had the highest Ca values, while multifloral pollens contained the highest Fe content. The samples from Ejere had the highest ash, Ca, Na and Cu content. The results showed a high content of the tested chemicals and a strong antioxidant capacity of bee pollen, varying with botanical and geographical origins. These findings would also serve as inputs for further assessment of the nutritional values of pollen for honey bee colonies and potential human consumption. However, comprehensive chemical investigations of larger number of samples representing diversified flora and locations are crucial to developing a broad regional information base on the nutritional profile of bee pollen.
An Autopsy Case of Acute Transformation of Myelodysplastic Syndrome Leading to Carcinomatous Cardiac Tamponade
Authors: Hatakeyama Junji , Ageishi Ryo , Kato Fumito
Published: June 2024

Introduction

We report a rare case of an 80-year-old male patient with acute transformation of myelodysplastic syndrome (MDS) in the pericardial cavity, leading to cardiac tamponade.

Case presentation

The patient had been diagnosed with MDS 7 months prior. One day before presentation, he suddenly developed dyspnea. At presentation, his blood pressure was stable, but he was in tachycardic atrial fibrillation; echocardiography revealed a pericardial effusion. Aortic dissection and acute myocardial infarction were excluded by examination upon admission. His blood pressure subsequently dropped, indicating pericardial tamponade. Pericardiocentesis was performed, and 800 ml of bloody pericardial fluid were withdrawn, stabilizing his blood pressure. The blasts ratio was higher in the pericardial fluid than in the peripheral blood; bone marrow examination revealed no evidence of acute transformation, but the presence of numerous cells with chromosomal abnormalities in the pericardial sac cavity confirmed acute MDS transformation. The patient died on day 15 due to progressive multiorgan failure. The autopsy revealed a neoplastic lesion extending circumferentially throughout the epicardium.

Conclusions

When a patient with an acute onset history of hematogenous pericardial effusion is found to have a pericardial tamponade of cancerous origin, acute transformation of MDS should be considered in the differential diagnosis.
The Impact of the Political System of the Republic of Serbia on Shaping Foreign Policy After 2012
Authors: Korzeniewska-Wiszniewska Mirella
Published: June 2024

Since 2012, the Republic of Serbia has been governed by the Serbian Progressive Party, and since 2017 its chairman has also been the president, who has full power in his hands. In the first years after taking power, this group implemented a policy that could have been surprising to public opinion, considering the fact that it separated from the Serbian Radical Party. The negotiations on Kosovo, which brought a number of agreements, the diplomatic offensive that created Serbia as a European partner and regional hegemon, dynamic progress in the EU accession process and the promotion of Western European values were the elements that noticeably exposed the change in the image of this country in relation to the previous decades. However, the second term of government began to fit into the pattern of the global phenomenon of populism, leading to the ruling group taking over the structures of the separation of powers and limiting democracy in the country. Subsequent general elections brought the strengthening of this party in the structures of the state, whose level of democracy was rated increasingly lower in international rankings. Moreover, the political system of Serbia itself began to be presented in scientific and expert analyses as an example of stabilitocracy. The aim of this topic is to analyse the specific power of President Aleksander Vučić and his party in relation to shaping the state’s multi-vector foreign policy.
A Study of Delhi Metro’s Magenta Line to Assess Commuter Satisfaction Post Covid-19
Authors: Khursheed Salman , Yasmin Shagufta
Published: June 2024

This study looks how satisfied people are with the Delhi metro, which is crucial for sustainable transportation. The study focuses on security, comfort, travel time components. The research shows how important the quality of service is in public transportation and how it affects what people think and if they would recommend it to others. In the research, 430 passengers surveyed and used statistical analysis to understand what factors influence people’s opinions. The study reveals that age, gender, comfort and security are important factors. The study also investigates the alternate PT modes and found that metro fare, seating/standing facilities are important aspects especially for different genders. It’s important for the DM to think about how people feel about the cost of using it, the seating, and the different preferences of men and women. Making changes like lowering fares and making the metro more comfortable could make it a better option for everyone in Delhi.
Charakterystyka usług turystycznych na Warmii i Mazurach na przykładzie działalności Fundacji „Moda na Warmię i Mazury” i Fundacji Puszczy Rominckiej
Authors: Lisowska Kinga , Łojko Majka
Published: June 2024

Tematyka podjęta w niniejszym opracowaniu dotyczy charakterystyki usług turystycznych na Warmii i Mazurach. Województwo warmińsko‑mazurskie jest jednym z najbardziej atrakcyjnych regionów Polski ze względu na wybitne walory przyrodnicze i kulturowe. Rozwój turystyki jest tu szczególnie ważny, bowiem turystyka stanowi jeden z najważniejszych sektorów gospodarki regionu. Badania przeprowadzono metodą analizy źródeł wtórnych. Zakres analiz obejmował działalność wybranych fundacji na rzecz realizowanych przedsięwzięć turystycznych na Warmii i Mazurach w latach 2006‒2023.
Uwarunkowania i możliwości uprawiania wybranych form turystyki na półwyspie Synaj
Authors: Ziółkowska-Weiss Kamila , Wszołek Iwona
Published: June 2024

Celem artykułu jest przedstawienie Półwyspu Synaj jako miejsca dającego możliwość uprawiania wybranych form turystyki – ze szczególnym uwzględnieniem turystyki religijnej, kwalifikowanej (aktywnej), przyrodniczej, wypoczynkowej oraz biznesowej. By zrealizować cel badania, posłużono się przeglądem literatury, analizą porównawczą i analizą SWOT oraz skonstruowano autorski model, dzięki któremu zilustrowano powiązania między poszczególnymi formami turystyki na Półwyspie Synaj. W przeprowadzonych badaniach wskazano, który z elementów analizy SWOT ma największe znaczenie dla rozwoju turystyki oraz jakie powiązania występują między poszczególnymi formami turystyki na omawianym obszarze. Autorki stwierdziły, że pomiędzy turystyką religijną a turystyką biznesową nie odnotowuje się żadnych wspólnych elementów, natomiast w pozostałych przypadkach każdorazowo można zauważyć, iż łączą się one ze sobą. Szczególną uwagę zwrócono na turystykę wypoczynkową, kwalifikowaną i przyrodniczą, które mocno łączą się ze sobą i wzajemnie ze sobą korelują. Chociaż na podstawie badań ustalono, że najmniejszą liczbę punktów otrzymała turystyka przyrodnicza, stwierdzono, że wyróżniają ją mnogość lokalizacji, różnorodność pod względem ukształtowania terenu oraz wyjątkowość formacji skalnych na skalę światową.
Overtourism and Local Political Debate: is the Over‑Touristification of Cities Being Observed through a Broken Lens?
Authors: Żemła Michał
Published: June 2024

The article aims to discuss how the mutual impact of anti‑tourism movements and politics influences the picture of overtourism disseminated by the media. The examples of Barcelona and Amsterdam presented show how anti‑tourism movements, and their postulates, merge with political programs and become a part of local or even domestic political debate. Politicians and supporting media have become interested in over‑heating emotions for political reasons. As a result, the picture presented in the media might not mirror precisely the complex phenomenon of overtourism being experienced differently in different places in the same city, at different moments, and by different residents.
Przedsiębiorczość kobiet w firmach rodzinnych – znaczenie płci w kształtowaniu przebiegu procesu sukcesji w polskich firmach rodzinnych
Authors: Klimek Sabina
Published: June 2024

Celem badawczym niniejszego artykułu jest analiza wpływu płci sukcesora przedsiębiorstwa i jego potomstwa na strategię sukcesji i rozwój firmy rodzinnej. Autorka przedstawia w artykule następującą hipotezę badawczą: Istnieje związek pomiędzy płcią potomstwa właściciela firmy rodzinnej a strategią sukcesji i przekazywania firmy kolejnemu pokoleniu. Niniejszy artykuł jest częściową analizą badania pt. „Realizacja wybranych celów Agendy ONZ 2030 przez przedsiębiorstwa rodzinne w Polsce”. Badanie obejmowało 200 firm rodzinnych w Polsce. Z uzyskanych wyników jednoznacznie wynika, że płeć potomstwa nie ma żadnego znaczenia w planowaniu sukcesji firmy. Ewentualne różnice w odpowiedziach przedsiębiorców były na tyle niewielkie, że nie mają one statystycznie żadnego znaczenia. Płeć potomstwa, czyli teoretycznie sukcesora, w przedsiębiorstwie rodzinnym nie ma żadnego wpływu na rozwój firmy, kontynuację jej działalności, czy też przekazanie kolejnemu pokoleniu. W związku z powyższym hipoteza badawcza nie została potwierdzona. Badanie pokazuje również, że decyzje o sprzedaży, zamknięciu czy kontynuacji działalności firmy były zupełnie niepowiązane z tym, jakiej płci są potencjalni przyszli sukcesorzy. Wyniki badania uzupełniają więc lukę badawczą w omawianym temacie i dają empiryczne dowody do debaty na temat sukcesji kobiet w przedsiębiorstwach rodzinnych. Zajmując się tym zagadnieniem, autorka przyczynia się do wzbogacenia literatury naukowej dotyczącej sukcesji w firmach rodzinnych.
تحليل مؤشرات التلوث البيئي للهواء باستخدام معطيات القمر الصناعي (Sentinel-5) لقضاء بلد
Authors: جاسم سعد حسن , سبع علي مخلف
Published: June 2024

يعد تلوث الهواء ابرز المخاطر التي تهدد حياة الإنسان والكائنات الحية لذلك أصبح من الضروري حل مشكلة تلوث الهواء للحفاظ على الحياة. ومن اهم ملوثات الهواء في منطقة الدراسة تتكون من العوامل البشرية التي لها الدور الفاعل والاساس في تلوث الهواء ومنها الزيادة في اعداد السكان و عوادم السيارات والحرائق والنشاط الصناعي و المولدات الكهربائية والنفايات وقد بينت الدراسة اهم الملوثات الغازية والتي تتكون من الغبار بأنواعه الدقائق العالقة والغبار المتساقط  وتم الاستعانة ببيانات القمر الصناعي (Sentinel-5)  لمعرفة اهم الغازات الملوثة للهواء وهي اول أكسيد الكربون وثاني أكسيد الكبريت  وثاني واكسيد النايتروجين والميثان وثاني أكسيد الكربون وتمكنت الدراسة من بيان الاثار الصحية لملوثات الهواء في منطقة الدراسة
التوزيع الجغرافي للعمليات الارهابية في محافظة كركوك والآثار الناتجة عنها للمدة(2011- 2022)
Authors: إبراهيم مصطفى ابتسام عبدالسلام , أسود الأحبابي نصيف جاسم
Published: June 2024

شهد العراق جرائم إرهابية متسارعة خلال السنوات العشر الماضية، إذ تعرضت محافظة كركوك بشكل خاص إلى جرائم إرهابية متكررة في نواحٍ عده منها، فقد ترك التباين المكاني في الظروف الجغرافية لمحافظة كركوك آثراً في ظهور المناطق الهشة داخل المحافظة، لذا هدفت الدراسة إلى التحليل المكاني للجرائم الإرهابية في محافظة كركوك بالاعتماد على البيانات والتقنيات الجغرافية المتاحة؛ فضلاً عن القاء الضوء على واقع العمليات الارهابية الحاصلة في محافظة كركوك والاثار التي ولدتها تلك التنظيمات ولاسيما (تنظيم داعش)، من خلال بعديها الزماني والمكاني.
ولتحقيق هدف الدراسة فقد تم الإعتماد على عدداً من المناهج البحثية والأساليب العلمية، فقد اعتمدت على المنهج الوصفي التحليلي من خلال جمع البيانات والمعلومات الجغرافية للتعرف على واقع العمليات الارهابية في محافظة كركوك، واستخدام المنهج التاريخي في تتبع اتجاهات العمليات الارهابية في المحافظة.
وقد توصلت الدراسة إلى أن تواجد التنظيمات والجماعات الإرهابية في محافظة كركوك لم يكن وليد الصدفة؛ بل تضافرت عدة مسببات وعوامل هيئت لها المناخ المناسب للظهور والانطلاق؛ إذ تباين الجرائم الإرهابية من منطقة إلى أخرى، وكان النصيب الأكبر منها في مدينة كركوك بحكم الحجم السكاني الذي تحتله في المحافظة بشكل عام، إذ بلغت اعلى نسبة للعمليات في مركز محافظة كركوك بنسبة بلغت(19,4%) وبكثافة بلغت(38,8) عملية ارهابية/كم2، حيث ظهر تركز العمليات الإرهابية على شكل نطاق يحيط بمركز محافظة كركوك وبالتحديد من جهة الشرق والجنوب والغرب واطراف المدينة؛ فيما تنخفض شدة التركز باتجاه الشمال والشمال الغربي بشكل تدريجي.
وأُختتمت هذهِ الدراسة بجملة من المقترحات، وكان أهمها ضرورة تكثيف المراكز الأمنية في البؤر الساخنة والمناطق الهشة أمنياً، التي تمثل الشريان الرئيسة لأي منطقة، فضلاً عن الحاجة الماسة للمزيد من الدراسات التي تهم بجغرافية الجريمة؛ بهدف مساعدة المؤسسات الأمنية على الحد منها، ومنع وقوعها.
التوقعات المستقبلية لظاهرة الهدر الغذائي في مدينة كركوك
Authors: خليل أمير أياد , جاسم احمد عبد الرزاق
Published: June 2024

تعد مشكلة الهدر الغذائي من اهم المشكلات التي تعاني منها معظم دول العالم والتي تؤدي الى نتائج سلبية في المجالات  الاقتصادية والاجتماعية والسياسية ، تناولت هذه الدراسة  التحليل المكاني لظاهرة الهدر الغذائي في مدينة كركوك لعام 2022 ، دراسة في جغرافية السكان، وتهدف الدراسة الى معرفة حجم الهدر الغذائي السنوي في مدينة كركوك وبيان توزيعها الجغرافي على مستوى الاحياء في المدينة ودراسة المتغيرات المؤثرة في ظاهرة الهدر الغذائي
   اعتمد الباحث في دراسته على المنهج  الوصفي والمنهج التحليلي الذي  يبحث في  العلاقات المكانية للظاهرة السكانية وتحديد العوامل المؤثرة فيها، واستخدام بعض  البرامج  الاحصائية من اجل الوصول الى نتائج دقيقة التي تخص الموضوع ، وخرائط  وشكال  بيانية اعتمدت على الحزمة الاحصائية لبرنامج Excel وspss و7.1.arc map10 لمعرفة التباين في الظاهرة  موضوع الدراسة (الهدر الغذائي)  فضلاً عن نتائج الدراسة الميدانية لعام 2022 ، لتعويض النقص الحاصل في البيانات ، وتم تمثيل الكثير من بياناتها في عدد من الخرائط التي احتواها متن هذه الدراسة .
Flash Diffusivity Measurement of Semiporous Insulation Material Intended for Radioisotope Thermoelectric Generators
Authors: McMasters Robert , Baarlaer Logan , Wang Hsin
Published: June 2024

This research involves the analysis of flash-heating data pursuant to find the thermal diffusivity of a semiporous insulation material (Min-K) that is being considered for use in a radioisotope thermoelectric generator (RTG). An RTG uses radioactive nuclear fuel to produce electricity through a temperature difference imposed on a bimetallic thermocouple. Insulation is required to protect sensitive equipment from high temperatures and to conserve heat in the fuel. Using flash diffusivity temperature data, various simulations were fitted in order to find the most appropriate heat transfer model for the experiments. Four models were allowed to compete, and the standard deviation of the residuals was compared for each model in evaluating model performance. The residuals are simply the difference in temperatures between the measurements and the mathematical models at each measurement point.
Between the Motherhood and Career Gripper: A Case Study of First-Time Mother
Authors: Doğutaş Aysun
Published: June 2024

Many women confront complex challenges when juggling motherhood with a profession, especially those who are starting their parenting journey for the first time. This case study explores Aisa's experiences as a first-time mother juggling her responsibilities as a caretaker with her desire to pursue a career in the business world. This study examines the complex dynamics, emotional challenges, and coping strategies used by a first-time mother as she tries to balance the demands of motherhood with her career goals through qualitative analysis of participant observations, semi-structured interviews, and field notes. Four themes have surfaced following the comprehensive data analysis. These themes include doubting her role as a mother, putting off her job goals, feeling guilty, and giving up on herself. The results highlight the complex interactions that exist between personal objectives, support networks, and society expectations, shedding light on the challenges that come with trying to strike a happy balance between motherhood and work. This study adds to a better knowledge of the difficulties faced by first-time mothers by providing insights into their lived experiences. It also helps develop strategies for empowering and supporting these women in both family and work settings.
Töreli Türk Edebiyâtı Çalışmaları-1 Su Kasîdesi (Şerh – Tahlil)
Authors: Aksoy Mustafa
Published: June 2024

Çalışmamızın amacı, Töreli Türk Edebiyâtı Çalışmaları-1 Su Kasîdesi (Şerh-Tahlil) adlı kitâbın genel hatlarıyla tanıtılması olup giriş kısmında Töreli Türk Edebiyâtı Okumaları hakkında kısa bilgi verilmiş akabinde kitapta gözetilen usûl hakkında bilgilerle kitaptaki yazarların isimleri aktarılmıştır. Kitap tanıtılırken dıştan içe doğru yöntemle, önce şeklî ve teknik bilgiler verilmiş daha sonra muhtevâ hakkında bilgiler verilmeye çalışılmıştır. Kitaptaki yazarların çok olması anlamlandırılmaya çalışılarak birbirleriyle uyum içinde olduklarından bahsedilmiş, kitaptan buna örnekler verilmiş, temennî ve teklîflerle ve serînin diğer kitaplarından bahsedilerek yazı sonlandırılmıştır.
Citizenship of Algerians During the French Colonial Period Between 1865 to 1919
Authors: Gündoğdu Badra
Published: June 2024

This study seeks to shed light on the issue of Algerian citizenship during the French colonial period between 1865 and 1919. And on the practices of the French administration in the context of its colonial policy of granting Algerians the status of French citizens and naturalizing them with French nationality under a series of unjust laws starting with the Senatus Consult Act of 1865 and the Crémieux Decree of 1870, passing through the People's Law of 1871, and ending with the Law of 4 February 1919 and the so-called reforms it introduced. Where all these laws were considered unfair to the Algerians (the indigenous population) were at the service of the colonial administration and brought no good to the Algerian people, the owners of the land, who rejected the policies of colonialism, colonization, oppression, and resistance for a free and independent Algeria.
This study aims to show that the French colonial administration made promises to Algerians by granting them French citizenship and granting them civil and political rights, but these promises were always conditional on a set of conditions accompanying Muslim Algerians leaving their Islam. This is an attempt by France to assimilate Algerians completely into the French entity and to eliminate everything that is Algerian, Islamic and Arab.
Bosna Hersek’te Okul Öncesi İslam Din Eğitimi Müfradatı Hakkında Kısa Bir Çalışma
Authors: Yavuz Alkılınç Sümeyye
Published: June 2024

Bosna Hersek tarih boyunca birçok inanca ev sahipliği yapmıştır. Dinsel çeşitlik açısında oldukça renkli bir coğrafya olmakla beraber bu durum beraberinde bazı zorluklarda getirmiştir. Bu çalışmamızda Bosna Hersek’te din eğitiminin güncel durumundan bahsedilmiş olup Bosna Hersek müfredatı baz alınarak Bosna Hersek’te ki okul öncesi İslam din eğitim müfredatı tanıtılmaktadır. Müfredatın daha iyi anlaşılabilmesi için öncelikle Bosna Hersek’te ki genel din eğitim serüvenine yer verilmiştir. Akabinde Bosna Hersek Okul Öncesi İslam Din Eğitim Müfredatına detaylı olarak yer verilmiştir Ayrıca din öğretimini yapan eğitimcilerde aranan şartlara ve süreçte kullanılan kaynaklara da değinilmiştir. Çalışmamız Haziran 2009 yılında Bosna Hersek İslam Topluluğu tarafından hazırlanan Din Eğitim Müfredatı Çalışmaları Okul Öncesi Kurumlarda Din Eğitim Süreci isimli, Bosna Hersek Din Eğitim Genel Müdürü Muharrem Ömerdiç tarafından imzalanan resmî belge esas alınarak hazırlanmıştır.
Türk Modernleşmesi, Tiyatro ve Yerli Oyun Temsilleri
Authors: Aktürk İbrahim
Published: June 2024

Osmanlı modernleşmesinin en önemli adımlarından birisi Tanzimat'ın ilanıyla birlikte başlayan süreç olmuştur. Tanzimat, Osmanlı Devleti'nin siyasetine, ekonomisine ve idari yapısına etki yaptığı gibi aynı zamanda kültür ve sanat yaşamını da etkilemiştir. Batı ile kurulan ilişki hem Osmanlı hem de Cumhuriyet döneminde Batı kültürünün, sanatının Anadolu coğrafyasındaki gelişimini de doğrudan etkilemiştir. Tiyatro sanatı da bu etkiden nasibi almış ve özellikle yerli eserlerin yazılması, yerli oyunların sahnelenmesi gibi konularda bu ilişkinin belirleyiciliği tartışma konusu olmuştur. Örneğin 1949 yılında kurulan Devlet Tiyatroları'nda yerli oyunlara geniş bir alan bırakılmamıştır. 2000 yılından sonraki süreçte ise Türk tiyatro kültürüne çok önemli katkılar sağlayan yerli oyun temsillerinde ciddi bir artış olduğu görülmektedir.
Pemberian Terapi Akupresur sebagai Upaya Peningkatan Kualitas Tidur dan Kadar Estrogen pada Wanita Menopause
Authors: Nainggolan Wiwiek , Mardiyono Mardiyono , Suwondo Ari
Published: June 2024

Penurunan hormon estrogen pada masa menopause menyebabkan kualitas tidur menurun. Kualitas tidur berpengaruh terhadap kesehatan fisik dan psikologi yang dapat menurunkan kualitas hidup menopause. Penelitian ini bertujuan untuk membuktikan pemberian terapi akupresur dapat meningkatkan kualitas tidur dan hormon estrogen pada wanita menopause. Desain penelitian ini adalah Quasi experiment yaitu dengan menggunakan kelompok yang sudah ada. Jumlah sampel sebanyak 40 responden, dipilih menggunakan teknik Consecutive Sampling. Kelompok intervensi diberikan terapi akupresur titik HT 7, PC 6, dan GV 20 sebanyak 6 kali selama 2 minggu. Kualitas tidur diukur dengan kuesioner Pittsburgh Sleep Quality Index (PSQI) dan kadar estrogen diukur dengan metode ELISA. Analisis data menggunakan Paired Sampel Test, Independent T-Test. Analisis data menunjukkan adanya perubahan rerata skor kualitas tidur dan kadar estrogen pada kelompok intervensi setelah diberikan intervensi terapi akupresur (p = 0,000 (effect size = 0.90). Hasil dari penelitian ini terdapat perbedaan rerata skor kualitas tidur dan skor kadar estrogen antara kelompok intervensi dan kontrol (p = 0,000) (effect size=1.17). Simpulan dari penelitian in adalah Terapi akupresur pada titik HT 7, PC 6 dan GV 20 dapat menigkatkan kualitas tidur dan hormon estrogen pada wanita menopause. Penelitian ini mengimplikasikan bahwa intervensi terapi akupresur dapat diterapkan sebagai bagian dari asuhan kebidanan  pada wanita menopause.
Body stalk anomaly – prezentare de caz şi discuţie
Authors: Maier Calina , Folea Diana , Vlădăreanu Radu , Tocariu Raluca , Şerban Marcela , Mitran Mihai , Brătilă Elvira
Published: June 2024

Body stalk anomaly is a term used to describe a pattern of severe defects that are incompatible with life. This con­d­ition should be suspected when encountering a large ab­do­mi­nal defect, along with axial skeletal abnormalities such as kyphosis or scoliosis and a short or absent umbilical cord. Body stalk anomaly is considered a fatal anomaly, thus being crucial to distinguish it from other anterior wall de­fects when evaluating the management options. We re­port the case of a patient diagnosed at 15 weeks of ges­ta­tion with a complex of severe fetal anomalies that were con­firmed after the termination of pregnancy as body stalk ano­maly, and we also discuss data published in literature re­gar­ding this topic.
Synthesis and Post-Assembly Modifications of Dynamic Covalent Boronic Ester [2]Rotaxanes
Authors: Yu Jingjing , Gaedke Marius , Das Satyajit , Stares Daniel L. , Schalley Christoph A. , Schaufelberger Fredrik
Published: June 2024

We report on the synthesis of [2]rotaxanes from vicinal diols through dynamic covalent boronic ester templates, as well as the use of the boronic ester for post-assembly modifications. A boronic acid pincer ligand with two alkene-appended arms was condensed with a linear diol-containing thread, and ring-closing metathesis then established a quasi[1]rotaxane architecture along with a non-entangled isomer. Advanced NMR spectroscopy and mass spectrometry unambiguously assigned the isomers and revealed that the quasi[1]rotaxane was in equilibrium with its hydrolyzed free [2]rotaxane form. The boronic ester handle in the quasi[1]rotaxane could also be synthetically addressed in a multitude of ways to obtain different [2]rotaxanes, including direct oxidation, protodeboronation, functional group interconversions and Pd-catalysed cross-couplings.
Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction
Authors: Kline Jake , Huang Jingjing , Lieu Linda , Srzentić Kristina , Bergen David , Mullen Christopher , McAlister Graeme , Durbin Kenneth , Melani Rafael , Fornelli Luca
Published: June 2024

Adeno-associated viruses are common vectors for emerging gene therapies due to their lack of pathogenicity in humans. Here, we present our investigation of the viral proteins (i.e., VP1, VP2, and VP3) of the capsid of adeno-associated viruses via top-down mass spectrometry. These proteins, ranging from 59 kDa to 81 kDa, were chromatographically separated using hydrophilic interaction liquid chromatography and characterized in the gas-phase by high-resolution Orbitrap Fourier transform mass spectrometry. Complementary ion dissociation methods were utilized to improve the overall sequence coverage. By reducing the overlap of product ion signals via proton transfer charge reduction on the Orbitrap Ascend BioPharma Tribrid mass spectrometer, the sequence coverage of each VP was significantly increased, reaching up to ~40% in the case of VP3. These results showcase the improvements in the sequencing of proteins >30 kDa that can be achieved by manipulating product ions via gas-phase reactions to obtain easy-to-interpret fragmentation mass spectra.
Synthesis of Vanillin from Biomass-Derived Isoeugenol Using Immobilized Cobalt-Porphyrin on Hydroxyl-rich Graphene Oxide Catalyst
Authors: Kaiprathu Anjali , Nishimura Shun
Published: June 2024

Synthesis of vanillin from isoeugenol by oxidation has been investigated using cobalt(II) porphyrin (CoTCPP: meso-tetrakis(4-carboxy)phenyl porphyrinato cobalt(II)) covalently linked to hydroxyl-rich graphene oxide (GOOH) as a heterogeneous catalyst. The catalyst was thoroughly characterized by various spectroscopic techniques, such as FT-IR, XRD, N2 adsorption-desorption, XPS, and SEM-EDS analytical techniques. Catalytic activity of the CoTCPP/GOOH gave an excellent yield of 75.1% in the conversion of isoeugenol to vanillin using molecular oxygen for 20 h reaction at 100 °C in 3.0 MPa oxygen pressure. The catalyst showed exceptional stability upon multiple reuses without significant loses in activity. Accordingly, the present study highlights the promise of CoTCPP/GOOH as a heterogeneous catalyst for the efficient aerobic oxidation of biomass-derived platform chemicals into valuable end-products.
Investigating Cavity Quantum Electrodynamics-Enabled Endo/Exo- Selectivities in a Diels-Alder Reaction
Authors: Wang Jialong , Weight Braden , Huo Pengfei
Published: June 2024

Coupling molecules to a quantized radiation field inside an optical cavity has shown great promise in modifying chemical reactivity. It was recently proposed that strong light-matter interactions are able to differentiate endo/exo products of a Diels-Alder reaction at the transition state. Using the recently developed parameterized quantum electrodynamic \textit{ab initio} polariton chemistry approach along with time-dependent density functional theory, we theoretically confirm that the ground state selectivity of a Diels-Alder reaction can be fundamentally changed by strongly coupling to the cavity, generating preferential endo or exo isomers which are formed with equal probability for the same reaction outside the cavity. This provides an important and necessary benchmark with the high-level self-consistent QED coupled cluster approach. In addition, by computing the ground state difference density, we show that the cavity induces a redistribution of electron density from intramolecular $\pi$-bonding orbitals to intermolecular bonding orbitals, thus providing chemically relavent description of the cavity-induced changes to the ground state chemistry and thus changes to the molecular orbital theory inside the cavity. We extend this exploration to an arbitrary cavity polarization vector which leads to critical polarization angles that maximize the endo=/exo selectivity of the reaction. Finally, we decompose the energy contributions from the Hamiltonian and provide discussion relating to the dominent dipole self-energy effects on the ground state.
A Short Overview of Benzalkonium Chloride in Pharmaceutical Sector: Safety, Environmental Impact and Alternatives
Authors: Wali Batool , Othman Niga , Rashid Sara , Hamid Sima , Issa Hayder
Published: June 2024

In this paper, an overview of the environmental and safety concerns of benzalkonium chloride (BAC), a chemical used extensively in pharmaceuticals, is provided. The topics covered include BAC processing, its various applications, toxicity, and environmental considerations. The industrial processing methods for BAC, its use as an excipient in drug compositions, and any negative consequences of BAC, are covered in this article. Because the concentration of BAC in formulations is often lower than 0.05%, the dose that is administered when it is utilized as an excipient is relatively modest. Additionally, the review draws attention to the potential allergic reactions that may take place after the initial administration of BAC. Alternative approaches to overcome the potential side effects of this medicine have also been addressed.
Materiality, Tactility, and Artmaking: An Exploration of Diasporic Trauma through Creative Pedagogy
Authors: Moussavi Yasaman
Published: June 2024

This paper explores the role of artmaking and tactile materials in learning and overcoming “stuckness” (Hage, 2009; Cangia, 2021), a state of discomfort caused by mobility constraints through an autobiographical approach. I explore how the tactile material artmaking processes can generate educational sites, and serve as a pathway to process trauma. The findings of this paper can empower learners to harness the therapeutic potential of artmaking, fostering resilience and growth through the creative process.
Technological Prejudice: Demonstrating the Ontological Challenge of Building a Critical Theory of Artificial Intelligence
Authors: Chamberland Émile
Published: June 2024

This paper contributes to a theory of artificial legal intelligence (ALI) that harmonizes concerns for artificial intelligence (AI) bias and prejudice with 1) the critical perspective, and (2) Jacques Ellul’s critique of the “technological phenomenon”. Necessary to this contribution is an argument for the importance of ontology in understanding the multidimensionality of ALI, and critical theory’s ability to deal with this multidimensionality. First, the paper introduces critical theory and some of its tenets. My focus then is critical legal studies (CLS) and their contentious relationship with the ontological issue of instrumentality. I emphasize that one way a theory of ALI can engage with this critical theme is through an ontological classification of AI. I propose two classifications: AI as a tool and AI as an ideological phenomenon. Each classification is attributive of a certain autonomy to AI and telling about a potentiality for domination a critical theory of ALI should recognize, deconstruct, and challenge. Ellul’s argument that the technological phenomenon is “autonomous” informs this part of my argument. I then discuss the concept of “prejudice” and find that, considering the ontological classifications, prejudice is visible in more than one form. Although the “algorithmic bias” approach is adequate for AI as a tool, it does not account effectively for another form of prejudice rooted in technology. I call it technological prejudice.
Fabrication and evaluation of some electrochemical properties of screen-printed electrodes for use in electrochemical analysis
Authors: Hoang Thai Long , Phan Trung Ngoc , Ho Xuan Anh Vu , Nguyen Dang Giang Chau , HO Van Minh Hai
Published: June 2024

Three types of conductive inks, including Ceres, Acheson carbon inks, and Ag/AgCl ink, were utilized to fabricate screen-printed electrodes (SPEs) on a 0.4 mm thick polyethylene terephthalate substrate using a screen-printing technique. To enhance the electrical conductivity, the printed electrodes were cured at 80°C for 90 minutes. The basic electrochemical properties of the self-made SPEs using these conductive inks were determined, evaluated, and compared with commercial SPEs from Metrohm. Although the electroactive surface areas of the self-made SPEs were not significantly different from those of the commercial SPEs, the heterogeneous electron transfer rates on the surfaces of self-made SPEs using Ceres and Acheson inks were inferior to those of the commercial SPEs. However, after pre-condition by applying a potential of +1.2 V for 180 s in a 2 M Na2CO3 solution, the electrochemical properties of the self-made SPEs, including the active surface areas and heterogeneous electron transfer rates, were significantly improved and became better than those of the commercial SPEs.
UHPLC-UV method validation for simultaneous quantification of vitexin and isovitexin from Santalum album L. leaves
Authors: Phan Thi Kim Phung , Le Minh Quan , Ngo Kien Duc
Published: June 2024

Santalum album L. is a precious medicinal herb with high economic value and has been extensively cultivated in Vietnam in recent years. Studies have revealed that the leaves contain two main active ingredients vitexin and isovitexin, which have demonstrated significant potential in treating diabetes, cancer, and inflammation. To contribute to the standardization of the title medicinal herb and its formula, a simple, fast precise and selective method for the simultaneous quantification of vitexin and isovitexin using ultra-performance liquid chromatography (UHPLC) has been developed and validated. The quantification procedure was performed on a Hypersil GOLD aQ Column (3 μm; 150 × 2.1 mm) at 35°C, with a mobile phase of acetonitrile (A) and and water with 0.1% formic acid (B), a flow rate of 0.3 mL/min, a detection wavelength of 336 nm, and an injection volume of 3 µL. The gradient program was set to 0.0-15.0 minutes, transitioning from 5% to 35% A, and 15.0-20.0 minutes, transitioning from 35% to 5% A. Validation of the quantification procedure, following ICH Q2 (R2) guidelines, demonstrated that the method achieved specificity, accuracy, precision, and linearity, with a high correlation between the peak area and the concentrations of vitexin and isovitexin (R2 values of 0.9998, respectively). Thus, the developed method can be utilized to determine the content of vitexin and isovitexin in Santalum album L. leaves, contributing to the standardization of medicinal herbs.
Effects of planting densities and regenerations on the growth and yield of Brachiaria humidicola grown in Thua Thien Hue province
Authors: Bui Van Loi
Published: June 2024

Brachiaria humidicola is a new grass grown for cattle feed. In this study, experiments were conducted in Thua Thien Hue province, including four treatments with four planting densities of 10 x 10 cm, 20 x 20 cm, 30 x 30 cm, and 40 x 40 cm through three regenerations. The first regeneration was 60 days old, and the next two regenerations were 40 days each from the previous harvests. The experiment aimed to evaluate the effect of planting densities and regenerations on the growth and yield of B. humidicola. The results showed that the tree height, grass bed height, and number of branches/tussock varied significantly between planting densities (p < 0.05), with the highest values observed at the planting density of 30 x 30 cm (96.33 cm, 73.38 cm and 40.17 branches/tussock, respectively). The fresh matter yield, dry matter yield, and protein yield of B. humidicola also showed significant differences (p < 0.05), achieving the highest values at the planting density of 30 x 30 cm (13.87, 3.69 and 0.97 tons/ha/generation, respectively). In general, the best growth and yield of B. humidicola were maximized through regenerations at the planting densities of 30 x 30 cm.
Gendered Advertisements: A Narrative Review of the Representation of Women in Masculine Product Advertisements
Authors: Debarati Dhar
Published: June 2024

Many discussions and arguments have been focused on the subjectification of issues relating to women in India. Talking about rural India and the issues of women encircling it, we could hardly reach a conclusive finding that a new issue would be jolting to join the puzzle of intertwined issues that prevail. Putting a step back and not venturing into the realm of rural India, women, and its issues, this paper will focus on urban India glaring at the issue of women and their objectification under the purview of media in the country. Media is a vast umbrella under which the studies could be undertaken. Be it in journalism, films, or advertisements, the presentation of women in the mediums and the understanding that has been created in the minds of the audiences leading to the further proliferation of a redundant narrative of viewing women as a sexual commodity had been constructed effectively. Lots of studies on the narrative have been accepted and further research has been made to understand the effects, causes, and possible solutions to end the unfortunate narratives that have been set. Yet, a detailed review of whether the situation remains the same today or certain developments in the regard have been made remains to be of particular interest. Hence, this paper seeks to evaluate the advertisement narratives through the lenses of perfume advertisements for men, taking into view the subjects of masculinity and the pacification of the male gaze and seeks to review whether changes have truly been made or remain in talks taking into account the development standards set by an urban society given attitudinal and behavioral development of the outlook towards women.
Anemia in Pregnant Women Correlated with The Estimated Fetal Weight
Authors: Ratna Puspita Sari  , Susanti Pratamaningtyas  , Dwi Estuning Rahayu
Published: June 2024

During pregnancy, the body's need for oxygen increases, causing an increase in erythropoietin production. An increase in plasma volume has an effect on fluid retention and blood dilution in pregnancy, causing a decrease in hematocrit, causing a decrease in Hb concentration and causing anemia. One possible impact is hampering fetal growth and development. The development of the fetus in the womb can be monitored by estimating the fetus's weight to detect fetal growth abnormalities early. This study aimed to understand the correlation between anemia in pregnant women and estimated fetal weight in the working area of the Sambi Health Center, Kediri Regency. The design of the study was cross-sectional, with a sample of 34 pregnant women with anemia. The sampling technique applied consecutive sampling. The instruments of the study were met line, Sysmex hematology analyzer and observation sheet. The results of this study were analyzed using the Kendall Tau test, and obtained a ρ value of 0.03˂α 0.05, namely H0 was rejected so that there was a correlation between anemia in pregnant women and the estimated weight of the fetus in the working area of the Sambi Community Health Center, Kediri Regency. When a pregnant woman experiences anemia, it results in disturbances in metabolism and exchange of substances in the tissues, then the placenta shrinks, resulting in a decrease in the transfer of important nutrients for the growth and development of the fetus. The impact of this situation is a slowdown in fetal growth which results in a low estimated fetal weight.
The Influence of Peer Group Education on The Quality of Life of Elderly with Hypertension
Authors: Istifani Putri Malinda , Widiharti Widiharti , Suminar Ervi , Sari Diah Jerita Eka
Published: June 2024

Hypertension is a prevalent issue commonly encountered among the aged population, which can significantly impact their overall quality of life. Peer Group Education might be considered as a viable approach to enhancing the overall well-being and quality of life among the aged population. Peer group education refers to the systematic dissemination of education and knowledge to cohorts of individuals who perceive themselves to share commonalities in terms of age, mindset, hobbies, or other relevant attributes with their peers. The objective of this study was to examine the impact of Peer Group Education on the quality of life among elderly individuals diagnosed with hypertension. The research employed a purposive sampling technique, targeting a population of 42 individuals residing in Palebon Duduksampeyan Village. The final sample size consisted of 38 participants. The independent factors were measured using a Standard Operating Procedure (SOP), whereas the dependent variable was assessed by a questionnaire on quality of life. Before peer group education, 36.8% of elderly individuals with hypertension reported a moderately bad quality of life; after peer group education, nearly 81.6% reported a reasonably excellent quality of life. These findings related to the impact of peer group education on the quality of life of elderly people with hypertension. The Wilcoxon ranks test was utilized to assess the impact of peer group education on the quality of life among senior individuals with hypertension. The resultant p-value was 0.008, with a significance level (α) of 0.05. The quality of life of older individuals residing in Palebon Village, Ponkesdes, is impacted by the presence of hypertension.
Stimulation, Detection, Early Intervention of Growth and Development: A Case Study of a Child with Speech Delay
Authors: Ulfah Mega , Dewi Mustika , Qonita Jihan
Published: June 2024

Speech delay is a condition where a child's speech and language development are significantly below the milestones of other children at the same age. The delay in school aged children will impact the child's enrollment in school. The purpose of this study was to describe stimulation, detection, and intervention in children with speech delay. The research used a qualitative approach with a case study design. The research population consisted of 97 children with speech delay. The inclusion criteria were children aged 2-3 years old, willingness to participate as respondents and presence during the research. The exclusion criteria were children with hearing loss, autism, attention deficit hyperactivity disorder (ADHD) and chromosome abnormalities. The sample was chosen by using purposive sampling technique. The subject was a child aged 32 months old. The data was collected through interviews, observation, and documentation. Based on the results of the study, it can be concluded that the child is classified as a functional speech delay caused by lack of stimulation. The child was first identified by parents having speech problems at the age of 18 months. Intervention was done through speech therapy. It is recommended that parents can stimulate and monitor children's development especially at the age of 0-2 years to avoid developmental problems, especially speech delay
How do Preservice Teachers Learn to Teach Integrated Computational Thinking?: Evidence from Planning, Enactment, and Reflection
Authors: Dektor Rachael , Severance Samuel , Tellez Kip
Published: June 2024

This study examines pre-service teachers’ (PSTs) beliefs and understandings about computational thinking (CT) integration and lesson implementation over time. Utilizing a design-based research approach, 3 PSTs led the co-design of integrated CT lessons with support from researchers and enacted these CT integrated lessons with K-5 students. All PSTs participated in a whole-group CT workshop and engaged in one-on-one lesson design sessions with a researcher. We utilized a grounded theory approach to qualitatively analyze pre-surveys, semi-structured interviews, and video data of three PSTs enacting their lessons. We found that PSTs’ initial beliefs about CT instruction – including the importance of it – were reinforced through their participation in our lesson design and implementation process. We also saw PSTs developed deeper understandings and more nuanced beliefs about the importance of CT integration and supporting multilingual learners (MLs) with English language development (ELD) strategies. PSTs also developed beliefs about what CT integration should look like and how it should be taught. This multiple case study demonstrates how providing rich design opportunities for PSTs to engage in CT integration work can support the productive development of PSTs beliefs about CT integration and their capacity for CT lesson design.