bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Politik Hukum Kaitannya Dengan Fungsi Pemerintah dalam Penetapan Upah Pekerja dalam Perspektif Asas Keadilan dan Asas Kepastian Hukum
Authors: Yuhaeni Wiwi
Published: May 2020

Sistem pengupahan perlu dikembangkan dengan memperhatikan keseimbangan antara prestasi atau produktivitas kerja, kebutuhan pekerja dan kemampuan perusahaan. Perumusan masalahnya adalah bagaimanakah implementasi politik hukum kaitannya  dengan fungsi pemerintah dalam penetapan upah upah pekerja dalam perspektif asas keadilan dan asas kepastian hukum.Metode penelitian menggunakan metode yuridis normatif dan pendekatan secara deskriptif analitis dan dianalisis secara kualitatif. Kesimpulannya berdasarkan UU No. 13 Th 2003 tentang Ketenagakerjaan, bahwa penghasilan yang memenuhi penghasilan yang layak ditujukan bagi pekerja/buruh dan keluarganya, sedangkan dalam Permenakertrans No.PER-13/MEN/VII/2012, kebutuhan hidup layak hanya ditujukan bagi pekerja/buruh saja atau pekerja status lajang saja. Sekarang berlaku PP No.78 Th 2015 tentang Pengupahan, dalam PP ini yang dikatakan hidup layak sama halnya dengan UU No.13 Th 2003 tentang Ketenagakerjaan. Jadi PP ini bukan semakin baik malah memperparah/ memprihatinkan  bagi pekerja seluruh Indonesia.
Penerapan Kedisiplinan Dalam Meningkatkan Kinerja Pegawai Badan Kepegawaian Pendidikan dan Pelatihan Kota Bandung
Authors: Yuaningsih Lilis
Published: May 2020

Dalam meningkat disiplin ASN pada Badan Kepegawaian, Pendidikan, dan Pelatihan Kota Bandung, salah satunya dengan menerapkan sistem absensi sidik jari. Namun dalam realitasnya masih terjadi pelanggaran disiplin yang dilakukan ASN dan adanya laporan terjaring ASN oleh tim penegakan disiplin ASN Kota Bandung. Dengan metode penelitian deskriptif kualitatif dan hasil penelitian menyimpulkan bahwa kebijakan disiplin Badan Kepegawaian Pendidikan dan Pelatihan Kota Bandung, belum maksimal dilaksanakan. Masih lemahnya sisi pengawasan terhadap pelanggaran disiplin pegawai. Perlu dilakukannya evaluasi berkala tim pertimbangan disiplin dan konsistensi penerapan Peraturan Pemerintah No. 53/2010 secara menyeluruh.
Perawatan Metode Kanguru (PMK) Sebagai Pengganti Inkubator Untuk Bayi Prematur
Authors: Kamila Lia , Elisa Fina
Published: May 2020

Abstract. Premature babies are at risk of causing complications such as thermoregulation temperature, oxygen desaturation, and intestinal motility. The main treatment for premature babies is in the incubator, but due to the limited use of the incubator, we need a method that similar to the way an incubator works for mother. Kangaroo mother care is an alternative treatment for premature babies that can be done by their mother. This method is done by placing the baby on the mother’s chest so that there is direct contact between the mother’s skin with the baby’s skin.

The purpose of this research is to determine the physiological responses in Premature Babies such as heart rate frequency, temperature and baby reflex before and after the kangaroo mother care in the government hospital city of Bandung.

This research uses a quasi-experimental method with one group pretest posttest design with 16 premature babies as a sample during June-July 2019. 

Result: before kangaroo mother care the average temperature of the baby is 36.4 0 C, the frequency of the heart rate 136 x / minute, babies who do not have a rooting reflex 50%, sucking reflex 68% and swallowing Reflex 100%. After kangaroo mother care has been given, the baby's temperature is 36.8 o C, the heart rate is 142 x / minute, babies already have 100% rooting reflex, 93.8% sucking reflex, and 75% swallowing reflex.

               The conclusion is there are significant differences in physiologic responses before and after kangaroo mother care.

Abstrak. Bayi prematur beresiko mengalami komplikasi seperti termogulasi suhu, desaturasi oksigen dan motilitas usus. Perawatan utama untuk bayi prematur adalah di dalam inkubator, namun karena keterbatasan penggunaan inkubator, maka diperlukan satu metode yang menyerupai cara kerja inkubator yang dapat dilakukan oleh ibu. Perawatan Metode Kanguru (PMK) merupakan salah satu alternatif perawatan bagi bayi prematur yang dapat dilakukan oleh ibu. Metode ini dilakukan dengan cara meletakkan bayi di dada ibu sehingga terjadi kontak langsung antara kulit ibu dengan kulit bayi.

            Penelitian ini bertujuan untuk mengetahui respons fisiologis pada bayi prematur yang terdiri dari frekuensi denyut jantung, suhu tubuh dan refleks bayi sebelum dan setelah dilakukan PMK.

Penelitian ini menggunakan jenis penelitian quasi experiment dengan bentuk rancangan One Group Pretest-Posttest. Sampel sebanyak 16 bayi prematur di RSUD Kota Bandung bulan Juni-Juli 2019.

Hasil penelitian menunjukkan sebelum dilakukan PMK rata-rata suhu bayi 36,4oC, frekuensi denyut jantung 136x/menit, sedangkan bayi yang belum memiliki refleks mencari 50% , refleks menghisap  68% dan refleks menelan 100%. Sesudah diberikan PMK rata-rata Suhu bayi 36,8oC, frekuensi denyut jantung 142x/menit, bayi yang sudah memiliki refleks mencari 100%, refleks menghisap 93,8% dan refleks menelan 75%.

Kesimpulan dari penelitian ini yaitu terdapat perbedaan perubahan respons fisiologis sebelum dan setelah dilakukan PMK.
Peningkatan Motivasi dan Hasil Belajar Analisis Hikayat Melalui Model Pembelajaran Kooperatif Tipe Nht Pada Kelas X Ma Daar El-Mu’Minin Kaduengang
Authors: Juwayni Muhamad , Marwah Marwah
Published: May 2020

Penelitian ini bertujuan untuk mengetahui motivasi dan hasil belajar siswa kelas X IPS MA Daar El Mu’minin Kaduengang Kecamatan Cadasari Kabupaten Pandeglang dalam menganalisis unsur intrinsik dan ekstrinsik hikayat melalui model pembelajaran kooperatif tipe NHT (Numbered Heads Together).

Metode penelitian yang digunakan adalah Penelitian Tindakan Kelas (PTK). Adapun desain penelitian ini  terdiri atas  2 (dua) siklus yang masing-masing siklusnya memiliki 4 (empat) komponen; perencanaan, pelaksanaan, pengamatan, dan refleksi. Dengan memanfaatkan instrumen penelitian, antara lain: lembar pengamatan (observasi), dokumentasi, dan soal tes, untuk memperoleh data hasil penelitian.

Berdasarkan data hasil penelitian yang dilakukan dapat dikemukakan beberapa kesimpulan sebagai berikut.

Pertama, motivasi belajar siswa dalam menganalisis unsur intrinsik dan ektrinsik hikayat dapat ditingkatkan melalui model pembelajaran kooperatif tipe NHT. Hal ini terbukti dari skor persentase pengamatan motivasi belajar siswa pada setiap siklusnya; pada siklus I skor rata-rata diperoleh 78.21%, dan pada siklus II skor rata-rata diperoleh 83.75%, terjadi kenaikan sebesar 5.54%.

Kedua, Hasil belajar siswa  setelah dilakukan metode pembelajaran dalam dua siklus melalui model pembelajaran kooperatif  tipe NHT, nilai rata-rata kelasnya mencapai 77.38 pada akhir siklus I, dan meningkat menjadi 80.95 pada akhir siklus II.

Ketiga, Penguasaan materi di atas KKM (75) yang ditetapkan oleh Madrasah terjadi peningkatan, pada akhir siklus I, tingkat penguasaannya mencapai 66.66% atau sejumlah 14 orang siswa dari 21 orang siswa, dan  setelah dilakukan perbaikan di akhir siklus 2 mencapai 90.47% atau 19 orang siswa dari 21 orang siswa.

Keempat, guru hendaknya dapat lebih memotivasi siswa untuk mengembangkan model pembelajaran kooperatif dalam kehidupan bermasyarakat siswa. Model pembelajaran kooperatif tipe NHT (Numbered Heads Together) perlu terus dikembangkan dan diterapkan pada pokok bahasan yang lain dan perlu adanya penelitian lebih lanjut sebagai pengembangan dari penelitian ini
Quelles compétences dans nos usines demain ?
Authors: Garbe Emmanuelle
Published: May 2020

Cette recherche s’inscrit dans une série de travaux interrogeant les effets de la digitalisation sur les métiers de l’industrie. Plus précisément, notre article propose de faire un focus sur un métier particulier, celui d’opérateur sur machine, et de regarder dans quelle mesure l’automatisation accrue des processus industriels redéfinit les compétences nécessaires au travail sur machine. En s’appuyant sur une étude qualitative menée au sein d’une grande entreprise industrielle, nous montrons que l’automatisation induit plusieurs changements qui posent question quant aux compétences actuelles et à venir des opérateurs sur machine à savoir, l’évolution de la relation homme-machine, la polarisation des compétences attendues et le renouvellement des pratiques de gestion des compétences.
Quaternary terraces of the Želivka River
Authors: Balatka Břetislav , Kalvoda Jan
Published: May 2020

This article presents the results of a geomorphological analysis of localities of Quaternary river terraces along the Želivka River and its historical-genetic interpretation in light of the formation of the Sázava terrace system. In addition, the morphogenetic characteristics of the Želivka Valley are presented and the fluvial sediments and terrace system of its river are described, including a chronostratigraphic correlation with other river terraces of the Bohemian Massif. Situational data concerning the Neogene sediments and Quarternary terraces of the Želivka River, including correlation with the Sázava River’s terrace system, are presented in Table 1. In accordance with current Quaternary stratigraphic classification, the entire system of terraces along both the Želivka and Sázava Rivers corresponds mainly with the Middle and Late Pleistocene, since the Cromerian Complex up to the Weichsel periods. The erosion phase previous to the accumulation of the first terrace in the Želivka and Sázava valleys belongs to the end of the Early Pleistocene. Older levels of fluvial sediments in the studied area, which are situated in a higher morphological position and which had previously been classified as Pliocene, have, therefore, been stratigraphically shifted into the Early Pleistocene.
Regional disparities and their evaluation in the context of regional policy
Authors: Viturka Milan
Published: May 2020

The article deals with the issue of disparities in regional development. The approach implemented in this study is based on a modified production function, a follow-up evaluation of the quality of business environment (including groups of businesses, labour, regional and local, infrastructural, price and environmental factors) and aggregate factors concerning both the utilization of human resources (including the unemployment rate and economic sensitivity) and innovative potential (including the innovative activities of companies according to results of a Czech Statistical Office survey and Association of Innovative Entrepreneurship databases). The indicated methodology was applied to 206 micro-regions in Czechia and calculated values were subsequently aggregated at the level of 14 Czech NUTS 3 regions (kraj). Evaluation of the results obtained led to the formulation of a number of recommendations for regional policy applications, in terms of both traditional and strategic concepts of regional policy.
Social capital as a factor in the development of peripheral areas: an analysis of selected components of social capital in Czechia’s typologically different peripheries
Authors: Jančák Vít , Chromý Pavel , Marada Miroslav , Havlíček Tomáš , Vondráčková Petra
Published: May 2020

This article explores regional differences in the social capital of peripheral areas in Czechia. Its objective is to make a general contribution to studies of social and human capital and to the clarification of the role of such capital in the polarisation of space. Specifically, the article builds on previous quantitative analyses of differences in human and social capital in Czechia by presenting analyses of selected results from an extensive empirical study, carried out in typologically different peripheral micro-regions in Czechia. Emphasis is given to an analysis of problems concerning residents’ level of participation in groups, according to a given region’s scale-level, residents’ trust in selected subjects (individuals, entities and institutions) and the overall satisfaction of residents with life in a given municipality. In terms of territorial differentiation, attention is focused on an analysis of differences in the quality of social capital in Czechia’s inner and external peripheries, in other words, in areas of continuous settlement and in border regions that were settled after the removal of the German speaking population.
Quando A Aula Não Tem Sala: Problematizações Sobre Jogos De Cenas Indisciplinares De Ensino E De Aprendizagem No Contexto Escolar
Authors: Roberta de Jesus Francis
Published: May 2020

A comunicação desenhada nesta escrita expressa o objetivo de praticar movimentos, dentre as possibilidades de construção de escolas outras, por meio de um modo de praticar a transgressão da organização disciplinar do processo de escolarização formal através da indicação de um percurso indisciplinar investigativo de observação de práticas já existentes nas escolas atualmente e que, de alguma forma, transgridam a forma disciplinar da escola pública que sejam transgressoras da forma disciplinar de organização da educação básica e das instituições escolares, no que diz respeito às práticas de ensino e de aprendizagem. Outro movimento é constituído pela intenção de ampliar as práticas indisciplinares observadas no contexto escolar por meio de práticas de problematizações dos campos de atividades humanas e das práticas socioculturais e jogos de linguagem que os componham e/ou que com eles, de alguma forma, se relacionem. Por fim, um último movimento, composto pela construção imaginativa de um tipo de registro que, de algum modo, toque a necessidade uma agenda que influencie o processo de instituição curricular formal para a educação básica e que projete e justifique funções outras, propósitos e intenções da escola pública, para o que a instituição realiza socialmente, para a educação formal e seus modos organizativos em relação aos processos de ensino e de aprendizagem na contemporaneidade, como potencialidade de transformação da obsolescência histórica da instituição escolar.
(Re)Existências Para Escolas Outras
Authors: Tamayo Carolina , Tuchapesk da Silva Michela
Published: May 2020

O presente artigo, busca trazer vozes que emergem numa escola indígena e não indígena de duas pesquisas em Educação Matemática a partir de lugares marginais, quais sejam: uma escola pública do interior do Estado de São Paulo, no Brasil e, uma escola pública numa comunidade indígena no Urabá antioquenho da Colômbia. A diversidade de cenários, configuradas em territorialidades diferentes, nos permitiram movimentar junto as teorias de Michel Foucault, Gilles Deleuze e as vozes dos sujeitos dessas pesquisas, discussões desde a escola e suas práticas e táticas de resistências. Deste modo, as vozes de revolta são apresentadas a partir de fragmentos de fala textualizados. Através de uma escrita rizomática, que do lado da informalidade, do inacabado, da deformação, abre e liberta, instiga e nos coloca no jogo do verdadeiro e do falso, abrindo margem para que linhas de fuga apareçam, produzindo outras escolas e escolas outras.
Escolas De Ontem E De Hoje Na Amazônia Paraense: Fissuras Em Prol Das Aprendizagens E Da Formação Docente
Authors: França dos Santos Rodrigues Isabel Cristina
Published: May 2020

O artigo se propõe a discutir a contação de histórias e a mediação de leitura enquanto movimentos integradores de ensino tensionando, decolonizando e criando alternativas de escolas outras a partir das fissuras proporcionadas pelas práticas escolares homogeneizantes e em contextos escolares públicos dos Anos Iniciais, a saber: uma escola ribeirinho-quilombola e uma na região metropolitana de Belém, na Amazônia Paraense, atendidas pelo projeto “Alfabetização, letramentos e docência na Amazônia”. As questões que nos atravessam e mobilizam em direção a estes movimentos são: a) quais as potencialidades e entraves da contação e da mediação de leitura no processo de ensino e aprendizagem? b) qual(is) perspectiva (s) formativa(s) subjazem das relações estabelecidas entre formadoras, licenciandos e docentes dos Anos Iniciais? Sendo assim, as dinâmicas propostas para inserção e disseminação desses movimentos são tratadas levando em consideração a perspectiva dos estudos Decoloniais e suas aproximações com os estudos da linguagem e suas interfaces. Para isso, consideramos as narrativas provenientes da comunidade ribeirinho-quilombola e os diálogos com a literatura Infanto-juvenil levando em consideração as identidades e as possibilidades de se reinventar dos sujeitos.
Currículo De Matemáticas Y Desarrollo En Debate: Reflexiones Desde Un Territorio Chocoano
Authors: Charry Oscar , Jaramillo Diana
Published: May 2020

Presentamos algunos avances de una investigación doctoral en curso, que se viene desarrollando con los maestros de la Institución Educativo Katío-Chamí en el municipio de El Carmen de Atrato (Chocó, Colombia). El objetivo de esa investigación doctoral es deconstruir terapéuticamente el currículo de matemáticas, disciplinarmente organizado, a partir de una problematización indisciplinar de prácticas sociales. En este artículo, pretendemos mostrar una problematización acerca del desarrollo, que posibilite desnaturalizar algunos enunciados que circulan en discursos oficiales en el campo de la educación matemática y, particularmente, en el campo del currículo. Esta problematización la realizamos considerando lo aprendido de las comunidades negras e indígenas del departamento del Chocó (Colombia), que nos han mostrado otras formas de concebir el desarrollo, alejadas de un legado eurocéntrico. En primera instancia, presentamos el territorio chocoano; en segundo lugar, presentamos algunos aspectos teóricos y metodológicos referidos a la terapia deconstruccionista; y, finalmente, presentamos, desde la mirada de comunidades indígenas y negras del Chocó, otras formas de concebir el desarrollo. Formas que se articulan con concepciones de escuelas otras, currículos otros, educaciones otras. Plan de vida, como alternativa al proyecto de desarrollo, es una propuesta que hacen comunidades indígenas del Chocó.
Fatores que impedem a adequação da oferta nutricional enteral em pacientes críticos
Authors: Walczewski Mayra da Rosa Martins , Walczewski Eduardo André Bracci , Wiggers Carolina Exterkotter Wiggers , da Rosa Beatriz Camilo , Marconato Francisco Henrique Cavalli
Published: May 2020

Introduction: Caloric protein malnutrition is prevalent in critically ill patients. This can be aggravated by an inadequate supply of enteral nutrition. Therefore, it is crucial to investigate nutritional adequacy and to identify the most frequent barriers to its administration. Methods: A longitudinalstudy was performed between June and December 2017 at the intensive care unit (ICU) of a hospital in the South of Santa Catarina, approved under the protocol 2.274.728. Patients ≥ 18 years, in enteral nutrition therapy (ENT) for ≥72 hours were included. Socio-demographic data,
ICU length of stay and nutrition therapy and laboratory tests were collected. Results: Among the patients in the unit, 147 were evaluated. Of these, 78.9% received ≥70% of the prescribed diet and 36.1% (n=53) started the EN only after ICU admission, with median onset of 20 (13-33) hours. The main reason for interruption of NET was fasting for procedures in 37.4% (n=55) of the patients analyzed. Nutritional inadequacy was associated with the presence of vomiting (p=0.012) and abdominal distension (p=0,009), such as shorter use of ENT (p=0.017) and longer time to ENT (p=0,046). Conclusions: The early start of the ENT is in line with what is recommended by
the guidelines. The most prevalent nutritional barrier was fasting for procedures. The presence of some gastrointestinal symptoms, such as vomiting and abdominal distention, shorter time to ENT and longer time to start of ENT appear to be associated with protein calorie inadequacy.
Há diferenças nas práticas de terapia nutricional entre pacientes pediátricos graves clínicos e cirúrgicos?
Authors: Hauschild Daniela B. , Ventura Julia C. , Oliveira Luna D. A. , Silveira Taís T. , Barbosa Eliana , Liberato Nilzete , Moreno Yara M. F.
Published: May 2020

Introduction: Pediatric critically ill patients admitted for surgical reasons may differ from medical patients. However, guidelines for nutritional therapy (NT) include both medical and surgical patients. The aim of this study was to describe the NT practices of critically ill children admitted for medical and surgical reasons. Methods: Prospective cohort study conducted with critically ill children, between 1 month and 15 years old, admitted in a pediatric intensive care unit. Patients who were discharged within the first 48 hours, died within the first 72 hours or who received oral NT were excluded. Clinical and demographic were collected. Nutritional status was assessed at admission and NT data from the first 7 days was collected. Chi-square and Mann-Whitney tests were
applied and p<0.05 was considered significant. Results: A total of 201 patients were included, with a median age of 2.2 years, 154 (76.6%) were admitted for medical reasons and 47 (23.4%) for surgical reasons. Compared to medical patients, surgical patients had a higher median age (5.0 vs. 1.4 years; p = 0.035), lower Pediatric Index of Mortality 2 (1.1 vs. 6.1%; p<0.001) and higher prevalence of complex chronic diseases (17 vs. 47%; p<0.001). There was no difference regarding nutritional status. Surgical patients showed higher median time for NT initiation (22.3 vs. 16.3 h; p=0.016), higher prevalence of parenteral nutrition (31.6 vs. 15.1%; p=0.019), lower energy (24.5 vs. 35.9 kcal/kg/d; p=0.003) and protein (0.82 vs. 0.99 g/kg/d; p=0.026) intake and higher prevalence of underfeeding (82.6 vs. 50%; p<0.001). There was a higher prevalence
of abdominal distension (36.2 vs. 21.4%; p=0.04) and constipation (38.3 vs. 16.9%; p=0.002) in surgical patients. Conclusion: Surgical patients were older, less severe, had longer time for NT initiation, higher prevalence of underfeeding and abdominal distension in the first 7 days. NT protocols should be individualized according to the reason for hospitalization.
Impacto da oferta proteica calórica em pacientes cardíacos críticos em nutrição enteral
Authors: Vieira Renata Monteiro , Barbiero Sandra Mari , Poloni Soraia , Vieira Silvia Regina Rios
Published: May 2020

Objective: The purpose of this study is to verify the impact of protein and calorie deficit with length of stay mechanical ventilation (MV) time, and death in critically ill patients in enteral nutrition (EN). Methods: Retrospective cohort study. Patients older than, 18 years, hospitalized in a cardiac intensive care unit (ICU), on exclusive EN were included. Data regarding daily infusion values of EN on the 5th and 10th day, beginning and maintenance of EN, hospital and ICU length of stay, and MV maintenance were collected in medical records. Results: A total of 155 patients were included, 61% male, mean age 73.23 ± 11.9 years; death within 30 days was 36.4%. Caloric adequacy on the 5th and 10th day was 52.45% and 62.71%, respectively; protein received in 10 days was 0.84 ± 0.29 g/kg/d. Those receiving less than 70% of the EN prescribed died 1.4 times more. Conclusion: Our findings suggest that receiving adequate diet reduces ICU mortality in cardiac patients.
Terapia nutricional parenteral domiciliar: perfil epidemiológico e prevalência das principais complicações em um serviço privado de Brasília, DF
Authors: Tallarico Roberta Teixeira , Caldas Alexandre Curvelo , Teles Leandro Marques de Mendonça , de Araújo Guilherme Teixeira , de Mendonça Ludmila Pinto Santiago , Farias Samara Jasielli Salvino Silva , Lima Paula Virgínia Sousa , Alves Juliana Tepedino Martins
Published: May 2020

Introduction: Home parenteral nutrition (HPN) is useful for patients with intestinal failure (IF), defined as gastrointestinal insufficiency to sustain nutrition or hydration without intravenous support. IF can be transitory, subacute or chronic, for this last one HPN is indicated. Objective: Epidemiology profile analysis of patients in a private setting in Brasilia, DF, Brazil, using HPN and its complications (infections, metabolic and hepatic). Methods: Retrospective study, using data base analysis of patients using HPN between October 2012 and May 2019. Results: Analysis of 22 patients, mean age of 52 years old, female gender prevalence (54.5%). IF causes: gastrointestinal tract neoplasm (44%), short intestine syndrome (12%), Crohn’s disease (8%). In total, 2.781 bag of HPN were used. The central lines catheters were PICC® (85.36%) and Hickman® (13.87%). Primary bloodstream infection (CLABSI) was present in 1.43 to 1.000 catheters/day and the pathogens isolated by cultures were: Gram positive coccos (50%); Gram negative bacilli
(25%); fungi (25%). Prophylactic lock therapy was used in 50% of the patients, hyperglycemia occurred in 31.81% and 36.36% had hepatic dysfunction. Complex and balanced lipid emulsion (CBLE) containing soya, olive and fish oil was used in 95.4% of the patients. The overall mortality was 63.6%, reducing to 26% when the oncologic patients were excluded. Intestinal recovery was present in 24%. Discussion: HPN has benefits and complications; the last ones can be reduced by the presence of a multidisciplinary team associated to patients and their caregivers training.
We found CLABSI prevalence similar to literature and by using lock therapy we might reduce it. Avoiding caloric overload, using CBLE and preferring cyclic infusion can prevent liver disease. Conclusion: The use of HPN has increased in the last decade, especially due to its capability of promote intestinal rehabilitation and improve quality of life. For an optimized, efficient and secure treatment a skilled team is mandatory.
Alterações no estado nutricional segundo IMC e perda de peso, em pacientes com câncer de cabeça e pescoço em uso de terapia nutricional enteral, em ambulatório de oncologia clínica em São Paulo
Authors: Machado Nathalia Soares , Querido Julia de Castro , de Oliveira Mayara Freitas , Magalhães Lidiane Pereira
Published: May 2020

Introduction: Head and neck cancer (HNC) patients constitute a recognized risk group for malnutrition due to several factors, and may require enteral nutritional therapy (ENT). This study evaluated alterations in nutritional status and weight loss in patients with HNC using ENT followed at the Universidade Federal de São Paulo (UNIFESP) oncology outpatient clinic. Methods: This was a retrospective study conducted
through database analysis, collected from January to December of 2018 at an UNIFESP oncology outpatient clinic. We selected all patients with HNC in use of ENT at some moment of the treatment during 2018. Weight and height were considered to calculate body mass index (BMI) and to classify nutritional status and the classification of weight loss for evaluation. Results: The sample consisted of 24 patients, 71% were elderly and 29% adults and 75% were men. At the first consultation in 2018, 6 (25%) patients were at normal weight and 15 (63%) had some degree of malnutrition (underweight).
A total of 11 (46%) patients reported previous weight loss. After the analysis it was found that 54% of patients had weight loss in the period, however, only 1 patient had severe weight loss. Changes in BMI were observed in all patients, but in 88% of the cases there was no change in BMI classification. Conclusion: Although patients were on ENT, many had weight loss, which may be a result of decreased food intake, metabolic abnormalities caused by tumor activity, or a consequence of treatment-related
symptoms. Most of the weight losses were not significant, and most patients had increased body weight, which may have been result of ENT use, which is responsible for delayed weight loss in cancer patients.
Prevalência e prognóstico de desnutrição determinados pelo critério GLIM
Authors: Laty Bianca Cristina , Bennemann Gabriela Datsch , Cavagnari Mariana Abe Vicente , Melhem Angélica Rocha de Freitas , Mazur Caryna Eurich , Schiessel Dalton Luiz
Published: May 2020

Introduction: Malnutrition is present in 25% to 70% of hospitalized patients, being caused by factors such as may predict an increased risk of complications, reduced response to treatment, lower quality of life, increased costs and length of hospitalization and increased mortality. Thus, the objective was to apply Global Leadership Initiative on Malnutrition (GLIM) to hospitalized patients and the association with age, gender, different pathologies and food intake. Methods: Longitudinal and retrospective study. Sociodemographic, anthropometric, clinical and dietary data were collected from adult patient nutritional records, evaluated between 2015 and 2018, in
two hospitals with specialized services and clinics that serve the Unified Health System (SUS). The univariate and multivariate multinomial logistic regression model (RLM) was used to determine the relative risk (odds ratio), adjusted for the following variables: age, sex, pathologies and food intake and compared with the GLIM classification. Results: Patients had significant weight reduction (usual weight to current weight) and % weight loss of -7.6% (95% CI -8.4 - -6.8). Age, pathologies, presence of inflammation, and reduced food intake all contribute to weight loss and malnutrition. The predominant diseases are highly catabolic and have a high response to the presence of systemic inflammation, specifically cancer patients who presented in the multivariate analysis chances of 2.21 times of being with moderate malnutrition and 2.72 times severe malnutrition. Conclusion: The prevalence of malnutrition was 46.8% of the total patients with significant relative risk regarding age, especially with cancer diagnosis and when reported reduced/inadequate food intake.
Perda de peso em pacientes oncológicos: prevalência e prognóstico relacionados a sexo, idade, localização do tumor e sintomas de impacto nutricional
Authors: Schiessel Dalton Luiz , Orrutéa Amanda Kamitani Góis , da Silva Sabrina Eduarda , Cavagnari Mariana Abe Vicente , Mazur Caryna Eurich , Gavarrete Diogo Dequech , Antunes Lindsay Bianca Buzato
Published: May 2020

ABSTRACT
Introduction: Cancer causes an increase in nutritional demands and the presence of of nutritional impact symptoms (NIS) contributes to reduction of nutrient intake and absorption, leading to weight loss, malnutrition and predicting overall survival. Assess the prevalence and predict the weight loss related to cancer, the Grade Scheme and the NIS. Methods: Data were collected from 2012 to 2018 from the first nutritional consultation of cancer patients in a clinic linked to SUS in the city of Guarapuava-PR. The primary outcome was to determine the % of weight loss (% WL), NIS and by the Grade Scheme proposed by Martin et. al (2015) the prognosis was determined by
univariate and multivariate Multinomial Logistic Regression (MLR) analysis (adjusted for age, sex and tumor location). Results: 1164 patients aged 56.9 years. In the first consultation, a 6.7 %WL was observed, and it was observed that 21.6% of the patients were underweight. The main sites and %WL were, respectively: Lung 140 (12.0%) and 9.4 %WL, Head and Neck 113 (9.7%) and 10.5 %WL, Colorectal 84 (7.2%) and 10.3 %WL, Stomach 90 (7.7%) and 13.7 %WL, Esophagus 85 (7.3%) and 14.0 %WL, Pancreas 24 (2.1%) and 16.1 %WL. The main NIS were: dry mouth (51.0%), abdominal pain (23.0%), constipation (21.7%), nausea (15.3%) and altered taste (10.5%). In the RML for univariate analysis, age, sex, cancer site and SIN and for multivariate analysis, all cancer
locations showed significant OR to be classified in grades 3 and 4. Conclusion: Before chemotherapy, weight loss and malnutrition are present. The cancer site and SIN increase the chance of the patient being classified in grades 3 and 4, leading these patients to a worse nutritional status and contributing to adverse results.
Comparative analysis of skin prick test with immunoblotting of different manufacturers in the context of determining the sensitization to birch allergen in patients with respiratory allergic diseases
Authors: Bogomolov Artemii
Published: May 2020

The aim of the study was to evaluate the diagnostic parameters of various methods for determining birch allergen sensitization in patients with respiratory allergic diseases – allergic rhinitis and bronchial asthma.
Materials and methods: During the study, 88 patients with allergic rhinitis and/or atopic asthma were examined with three different methods of specific allergic diagnosis (in vivo and in vitro) according to the recommendations of the ethics committee of the Pirogov Vinnitsa National Medical University, all of which were out of acute. Inclusion criteria were a diagnosis of allergic rhinitis (both intermittent and persistent) and/or atopic asthma. The pre-test was conducted according to the classic test method according to the normative documents with commercial allergen extracts. Western blots for the determination of IgE levels were performed using RIDA AllergyScreen test systems (R-Biopharm AG, Darmstadt, Germany) and Euroline (Euroimmun).
Results and discussion: Systematic error of measurement results of immunoblot of different manufacturers is equal to 2.27 ku/l, which indicates the presence of a systematic difference. The distribution graph corresponds to the type of absolute systematic error graphs. The standard deviation of the difference was 11.28, which is significantly compared to the values themselves.
Thus, the results of the two systems for the determination of specific IgE for birch allergen by the Rida AllergyScreen and Euroline methods are not well matched due to systematic divergence of indicators.
There is a good agreement between the results of skin testing with birch allergens and the detection of specific IgE by the Rida AllergyScreen test, and between the results of skin testing with birch allergen and the detection of specific IgE by the Euroline method, there is a moderate agreement between the results.
Analysis of expression of molecular marker KI-67 in patients with laryngeal cancer for regional metastases and recurrences
Authors: Kovtunenko Alexander , Tymchuk Sergey , Shportko Bogdan
Published: May 2020

Background: Laryngeal cancer is a common localization of squamous cell carcinoma of the head and neck. The main factor influencing the survival of patients is the presence of regional metastases. The malignant degeneration of a cell is always accompanied by disruption of the cell cycle, in particular a sharp increase in proliferative activity. The molecular marker Ki-67 is used to investigate the proliferative activity of tumor cells.
Aim of the study: To study the informative content of immunohistochemical investigation and to determine the expression of the molecular marker Ki-67 in patients with laryngeal cancer, prior to the prediction of regional metastasis and relapse.
Materials and Methods: 70 patients with cancer, stage III-IV (T3-4N0-3M0) clinical group II were under observation. Of these, 39 patients from the main group were with regional laryngeal cancer metastases, and 31 patients in the comparison group – without revealed regional metastases. Patients' age ranged from 33 to 74 years. The average age was 61.9 years. Male patients made up the absolute majority of 99% No = 69. All patients were histologically diagnosed with squamous cell carcinoma. Monoclonal antibodies to Ki67 (TermoScientific, USA) were used as the primary molecular markers. The proliferation index (PI) was rated as low in the range of 0-30% and as high in more than 30% of positive cells with an intranuclear label.
Results: The study of molecular markers Ki-67 showed its expression at 69 [60.2; 77.5]% (Me [25%; 75%]) for the squamous cell laryngeal cancer group, without metastases – 60 [29; 70.5]%, for the group with metastases – 72 [67; 80]% (P <0.001).
In statistical data processing, the AUC value (0.777) was set for Ki-67 for metastasis and showed an increased degree of expression for laryngeal cancer metastasis. Ki-67 has a good diagnostic value and can be used as an additional method for predicting regional laryngeal cancer metastases. However the practical use of this marker as a prognostic one for determining the volume of surgery on the lymphatic structures of the neck requires further investigation.
It should be noted that this study did not reveal the link of Ki-67 AUC (0.588) with the degree of differentiation of laryngeal cancer and its recurrence, but more in-depth study of molecular markers in the future may reveal other patterns of tumor growth and be used in the prognosis and personalization of treatment.
Conclusion: Expression of Ki-67 allowed to accurately predict tumor metastasis. A 1% increase in Ki-67 expression resulted in an 8.3% increase in the chance of tumor metastasis (95% CI - 1.043-1.142), and the age dependence on metastasis is not reliable.
Determination of expression of Ki-67 does not accurately predict the possibility of recurrence of laryngeal cancer (p=0.27; AUC (95% CI) – 0.588 (0.414-0.763)) herewith age dependence of chance of a recurrence was not revealed.
Postsurgical rehabilitation of patients with chronic rhinosinusitis
Authors: Bezshapochny Sergey B. , Loburets Valery V. , Loburets Andrey V. , Dzhirov O.R.
Published: May 2020

Topicality: Modern rhinosurgery in tht treatment of chronic rhinosinusitis based of tht principles of maximum preservation of the functional anatomy of the nasal cavity. This helps to improve not only the healing process but also tht quality of life of the patient. Functional endoscopic surgery (FESS) is tht most effective treatment lor chronic rhinosinusitis today. This method helps to accelerate the recovery of patients and reduce the number of postoperative complications, which in turn reduces the need lor surgery. But apart from meticulous and careful surgical technique, one of the most important places in the treatment of the patient is optimal management after surgery, for maximum potentiating of recovery. The relevance of the study is due to the need to further improve the pharmacotherapy of the postoperative period. This article high lights several different therapies aimed at the fast test restoration of the physiological work of the nasal structures.
Materials and methods: In total, 50 patients were divided into three groups as part of the study. Group 1 received an isotonic solution of 0.9% NaCl from day one and topical glucocorticosteroids (Mometasone furoate) from day 7. In group 2A, phytopreparation was added to classic therapy and 0.9% NaCl was used instead of the standard saline solution, with 0.4% CO2 added.
Evaluation of the effectiveness of treatment was performed using a visual-analog scale lor subjective symptoms and endoscopic examination using the scale of The Modified Lund-Kennedy Endoscopic Score lor objective symptoms.
Results: On the 7th day, statistically significant differences were observed according to VAS data between patients of the 1st
and 2B groups in terms of nasal discharge (p<0.05, U=77.5) and impaired olfactory function (p<0.05, U=75), in the same period a statistically significant difference was observed between MLK indices in patients of 1st and 2B groups (p<0.05, at U=73)
No side effects of the drugs used in the study were detected.
Conclusion: Based on the study, it can be concluded tht the use in the postoperative period of the proposed drugs have a significant clinical advantage, which is based of clinical studies and confirmed by the principles of evidence-based medicine.
KONTRIBUSI KEKUATAN, KECEPATAN, KELINCAHAN DAN PERCAYA DIRI TERHADAP KETERAMPILAN TEKNIK PADA PERMAINAN FUTSAL
Authors: Arham Syarifuddin
Published: May 2020

Tujuan peneliitan ini adalah untuk mengetahui kontribusii seberapa besar kontribusi kekuatan, kecepatan, kelincahan dan percaya diri terhadap keterampilan teknik permainan futsal. Metode penelitian yang digunakan adalah penelitian deskriptif korelasional dan inferensial. Hasil penelitian menunjukkan bahwa ada kontribusi yang signifikan kekuatan, kecepatan kelincahatan da percaya diri terhadap keterampilan teknik permainan futsal siswa SMA Negeri 8 Makassar. Kesimpulan bahwa percaya diri memiliki kontribusi yang paling besar dibandingkan dengan kekuatan, kecepatan dan kelincahan terhadap keterampilan teknik pada permainan futsal.
Analisis Motor Ability Terhadap Kemampuan Lompat Jauh Mahasiswa Prodi Ilmu Keolahragaan FIK UNM
Authors: Sulaeman Sulaeman
Published: May 2020

Sulaeman, 2019. Analisis Motor Ability terhadap kemampuan lompat jauh mahasiswa Prodi Ilmu Keolahragaan FIK UNM.

Penelitian ini bertujuan untuk mengetahui apakah ada kontribusi Motor Ability terhadap kemampuan lompat jauh mahasiswa Prodi Ilmu Keolahragaan FIK UNM.

Populasi dan sampel adalah mahasiswa Prodi Ilmu Keolahragaan FIK UNM yang diambil melalui tehnik purposive sampling. Tehnik analisis data yang digunakan adalah analisis deskriptif, uji normalitas, uji linearitas dan uji regresi dengan menggunakan fasilitas computer melalui program SPSS.

Berdasarkan hasil pengujian analisis data Motor Ability terhadap kemampuan lompat jauh mahasiswa Prodi Ilmu Keolahragaan FIK UNM diperoleh nilai regresi 0,939 dengan tingkat signifikan 0.000 < α0.05, untuk koefisien determinasi sebesar  0.800. hal ini berarti 80% pengaruh Motor Ability terhadap kemampuan lompat jauh pada mahasiswa Prodi Ilmu Keolahragaan FIK UNM.

Hasil analisis statistik menunjukkan bahwa ada kontribusi yang signifikan Motor Ability terhadap kemampuan Lompat Jauh. Apabila hasil penelitian dikaitkan dengan teori dan kerangka pikir yang mendasarinya, maka hasil penlitian ini mendukung dan memperkuat teori maupun hasil penelitian yang sudah ada sebelumnya. Penelitian ini juga menjawab Hipotesis penelitian bahwa ada kontribusi yang signifikan Motor Ability terhadap kemampuan lompat jauh pada Mahasiswa Prodi Ilmu Keolahragaan FIK UNM

 

Kata Kunci: Motor Ability, Lompat Jauh
Heteronuclear Metal-organic Frameworks; Adsorption and Luminescence Aspects
Authors: Imran Muhammad , Kanwal Farah , Latif Shoomaila , Iqbal Zafar , Mitu Liviu
Published: May 2020

Synthesis of heteronuclear metal organic frameworks (1 & 2) using 4-mercaptobenzoic acid (H2MBA) and 2,6-naphthalenedicarboxylic acid (2,6-NDA) was carried out followed by successful characterization with FTIR, SEM, EDX, 1H-NMR, TGA and PXD. Brunauer-Emmett-Teller (BET) and luminescence studies of these MOFs were also investigated.
Synthesis, Characterization and Biological Evaluation of New Schiff Base Ligand derived from 3-hydroxy-benzaldehyde and p-toluidine and its Divalent Metal Ions
Authors: Mazhar Noreen , Aftab Mehwish , Mahmud Tariq , Basra Muhammadasim Raza , Akhtar Mansoor , Mitu Liviu
Published: May 2020

A new Schiff base ligand (L) and its transition divalent metal complexes were prepared by the condensation reaction; Reaction was carried out at 70-80 oC by refluxing equimolar ratio of toluidine and aldehyde by continuous stirring for 5-6 hours. Synthesized ligand and Ni(II), Fe(II), Co(II), Mn(II) and Zn(II) bimetallic complexes were characterized by using FT-IR, UV-visible spectroscopy, AAS, Single crystal X-ray analysis, 1H-NMR, molar conductance. Compounds were screened against two fungus Candida glabrata and Candida albicans by agar tube dilution protocol. In vivo anti-inflammatory activity via induced paw edema method and in vitro results by heat induced protein denaturation method were checked. Synthesized compounds were also showed antioxidant activity by using DPPH (diphenylpicrylhydrazyl) and Trolox was used as standard. These studies show that ligand and almost all metal complexes are reactive towards biological assays against reported standard drugs. Zn-L indicates more activeness for antioxidant activity and free ligand while Co-L recognized as more effective anti-inflammatory drug.
Effects of Fe and Mn on Microstructure and Microhardness of Titanium Alloys
Authors: Geanta Victor , Voiculescu Ionelia , Tudoran Stefan
Published: May 2020

Titanium is one of the most appreciated biocompatible materials, as it possesses both good mechanical characteristics but also high corrosion resistance in contact with biological environments. Initially, Ti-6Al-4V trade mark was used for the manufacture of implantable medical devices, being usually selected for making aerospace structures. Over time, it has been found that aluminum and vanadium are not elements with acceptable biocompatibility, metallic ions being found either dissolved or accumulated in certain areas adjacent to the implants. Therefore, the development of titanium alloys dedicated to biomedical applications is still highly required. The effects of chemical elements (Al, Fe and Mn) on the microstructure and microhardness of titanium alloys for medical applications are analyzed in the paper. The experimental alloys were obtained by melting of raw materials in an argon inert atmosphere of the VAR equipment, using high purity metallic elements. Has been developed Ti-base alloys that contain different concentration of 11 to 18 wt. % Al, 2 to 7wt. % Fe and 6 wt. % Mn for highlighting the effects of these elements on the micro-structure and microhardness of titanium alloys. SEM and EDAX analysis revealed the microstructure and microhardness changes occurred by using of alpha stabilizing elements (Al) or beta stabilizers (Fe, Mn).
A Molecular Docking of New 9β-Halogenated Prostaglandin Analogs with an Ester Group at C-6 Atom of the α-Side Chain
Authors: Tanase Constantin I. , Pintilie Lucia , Mihai Elena
Published: May 2020

Prostaglandins with cytoprotective activity were studied for a long time and a few PGE1 and PGE2 stable analogs were promoted as drugs: arbaprostil, enprostil, misoprostol and rioptostol. Nocloprost, a 9β-chlorine prostaglandin analog, has been also promoted as a cytoprotective drug; the succes with this compound stimulated the reserches, and many 9β- or 11β-substituted prostaglandins were synthesized and studied for their biological activity. In the same dirrection we previously synthesized new 9β-halogenated prostaglandins having also an ester group at the carbon atom 6. These compounds were now used in a molecular docking study to predict their potential cytoprotective (anti-ulcer) activity. The study has been done with CLC Drug Discovery Workbench 2.4. software and an oxidoreductase enzyme receptor, chosen from the Protein Data Bank, ID: 4KEW. Two recognized drugs, omeprazole (co-crystallized with the enzyme) and nocloprost were used as standard in the study. The 9β-halogenated prostaglandin analogs were finally docked. Nocloprost and all 9β-halogenated compounds had docking score greater than that of omeprazole. The majority of the 9β-halogenated analogs have a docking score even greater than that of nocloprost, indicating that these compounds could have potential cytoprotective activity. Correlations between docking score and substituents on the prostaglandin skeleton have been done.
Heavy Metalspatial Distribution and Pollution Assessment in the Surface Sediments of the North � Western Black Sea Shelf
Authors: Bucse Andra , Vasiliu Dan , Balan Sorin , Parvulescu Oana Cristina , Dobre Tanase
Published: May 2020

22 surface sediment samples were collected in August 2018 from the Romanian inner shelf (Nord-Western Black Sea). Concentrations of some metals (Al, Cr, Cu, Ni, Zn, As, Pb, and Hg), TOC content, and grain size of sediment samples were determined by specific techniques. The order of accumulation of heavy metals was Zn]Cr]Ni]Cu]Pb]As]Hg. Multivariate analysis indicated that As, Ni, Cu, Zn, Pb, and Hg concentrations had similar behavior and they were positively correlated with the clay content, whereas Al and Cr concentrations presented close patterns and they were negatively correlated with the water depth. Sediment pollution assessment indices (enrichment factor, contamination factor, and geo-accumulation index) suggested no/low pollution for most of the metals analyzed, excepting for Pb and Hg (moderate pollution). Values of pollution indices highlighted a higher sediment pollution with Pb and Hg along the Danube�s plume direction, in the oil platform area (eastern edge of the Portita Bay), and partially in the Constanta and Mangalia area, suggesting the influence of port activities, tourism, urban wastewater discharges, oil and gas extraction.