bluuebunny/crossref_metadata_2025 huggingface dataset:
Mauquf’alaih as a waqf accountability center (prophetic social approach)
Authors: Ngaini Siti Nur , Sholihin Mahfud
Published: November 2023

Purpose - This study aims to explore Kuntowijoyo's prophetic social thinking to make mauquf ‘alaih the main focus of waqf accountability.Method - This research is a conceptual paper that attempts to construct the concept of waqf accountability in a prophetic social approach.Result - The author's opinion emphasizes the rights of the mauquf ‘alaih by highlighting how the accountability role of waqf needs to shift emphasis from serving stakeholders hierarchically to being re-engineered towards beneficiaries (mauquf ‘alaih). This requires a reconceptualization of the meaning of waqf, which must be seen as part of a wider effort to achieve social justice and the welfare of the ummah. In this case, the prophetic social value is considered as the conceptual framework.Implication - Theoretically and contextually prophetic social principles are able to give birth to a reorientation of waqf accountability towards deeper humanist and emancipatory realizations, as well as more holistic and religious accountability practices.Originality - This research is the first study that used prophetic sosial approach in waqf accountability.
Bank social fund distribution and cost of profit-sharing investment account: evidence from Indonesia
Authors: Jayanto Prabowo Yudo , Mukhibad Hasan , Aziz Nana Abdul
Published: November 2023

Purpose - This study aims to prove the impact of the distribution of social funds (qardhul hasan-QH and zakah funds) on the cost of a Profit-Sharing Investment Account (PSIA) immediately and for a long period in Islamic banks.Method - The research is based on panel data from 11 Islamic commercial banks (IB) in Indonesia from 2009 to 2021. Data were analyzed using the generalized least squares (GLS) random-effects method with robust standard error.Result - This research proves that the distribution of social funds (the distribution of QH and zakah funds) has a positive economic impact in the short period but the distribution of social funds has a negative economic impact in the long period.Implication - This study contributes to bank directors in considering the social activities of banks funded by QH funds by considering the effectiveness of social fund distribution, hence having positive economic consequences for bank performance.Originality - This research contributes to the development of previous literature in two ways. First, we use CSR performance proxies that are different from previous studies, namely the distribution of QH and zakah funds. The distribution of these funds is a proof of the bank's legitimacy to care about social, economic, and environmental issues. Second, we use the cost of PSIA as an economic consequence of CSR performance.
Performance of Indonesia Sharia companies: Does corporate ethical identity matter?
Authors: Hartyanti Irma , Harto Puji , Wangbenmad Chutima
Published: November 2023

Purpose - The development of Islamic finance has made many Indonesia sharia companies register themselves as part of the Indonesia Sharia Stock Index (ISSI). The government always encourages sharia economic growth that upholds ethics. From the Islamic perspective, ethics is the foundation of all aspects of life. This study aims to analyze the performance of Indonesia sharia companies, by linking the importance of Corporate Ethical Identity (CEI) which is implemented in corporate culture.Method - Quantitative research is reviewed through the annual reports of manufacturing companies registered at ISSI for the 2018 and 2019. Linear regression analysis, along with moderated regression analytics, was used to analyze data from 154 manufacturing companies.Result - The results of the study show that CEI has a positive influence on firm performance, and ownership structure as a moderating variable strengthens the influence of CEI on firm performance.Implication - Sharia companies in Indonesia are advised to increase CEI reporting so as to improve financial performance in accordance with sharia principles.Originality - This study represents the inaugural investigation into CEI within Islamic companies operating in Indonesia, with a specific emphasis on corporate culture. The novelty in this research is the focus on company culture, and what distinguishes it from the mentioned study is the utilization of the ownership structure concept as a moderating variable. It also incorporates the utilization of the ownership structure concept as a moderating variable.
Cistus creticus Ekstrelerinin Kontrollü Salımını Gerçekleştiren Katı Lipid Nanopartiküllerin (KLN) Geliştirilmesi ve Antimikrobiyal Ekinliklerinin Araştırılması
Authors: ERDOĞMUŞ Sevim Feyza , DURMUŞ Şerife Nur , ÖZDEMİR Saniye
Published: November 2023

Bu çalışmanın amacı, tıbbi ve aromatik bitkiler arasında yer alan Cistus creticus ekstreleri yüklü kontrollü salım yapabilen katı lipid nanopartikül sistemleri geliştirmek ve bu sistemlerin patojen test mikroorganizmalara karşı antimikrobiyal etkinliğini araştırmaktır. Çalışma kapsamında C. creticus yapraklarından etanol ve su ekstresi ultrasonik yöntem kullanılarak elde edilmiştir. Bu ekstrelerinin yüklü olduğu katı lipid nanopartiküllerin karakterizasyonu SEM, DLS analizleri ve zeta potansiyelleri, in vitro salım profilleri ile değerlendirilmiştir. Etanol ve su ekstreleri yüklü katı lipid nanopartiküllerin boyutları sırasıyla 40-90 nm, zeta potansiyelleri –35.5 ve -30.7 mV ve PDI değerleri 0.455 ve 0.475 olarak saptanmıştır. Elde edilen katı lipid nanopartiküllerin patojen test mikroorganizmaları (Listeria monocytogenes ATCC 19115, Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae NRRLB 4420. Pseudomonas aeruginosa ATCC 27853, Enterococcus faecalis ATCC 51289, Escherichia coli ATCC 35218, Escherichia coli ATCC 25922) üzerindeki MİK değerleri 1.56-25 mg/mL aralığında değişiklik göstermektedir. Kuyu difüzyon testi sonuçlarına göre ekstre yüklü katı lipid nanopartiküllere karşı mikroorganizmalar, duyarlı, orta derecede duyarlı ve dirençli olarak belirlenmiştir. En yüksek antimikrobiyal etki etanol ekstresi yüklü nanopartiküller için zon çapı 19±0.75 olarak L. monocytogenes ATCC 19115’e karşı tespit edilmiştir.
4-buthoxyphenyl 4’-hexylbenzoate Sıvı Kristal Molekülünün Geometrik Yapısının İncelenmesi
Authors: ÖZDEN Pınar
Published: November 2023

Bu çalışmada, tek eksenli moleküler simetriye sahip bir termotropik nematik sıvı kristal olan BPHB (4-buthoxyphenyl 4’-hexylbenzoate) molekülünün geometrisi optimize edilmiştir ve spektral analizleri yapılmıştır. Bu amaçla Gaussian09 yazılım paketi ve GaussView 5.0 grafik ara yüz yazılım programları kullanılmıştır. Hesaplamalar Hartree-Fock HF/6-31G(d,p) ve yoğunluk fonksiyonel teorisi DFT/B3LYP/6-31G(d,p) yöntemleriyle gerçekleştirilmiştir. Optimize edilen yapının moleküler ve termodinamik yapısal parametreleri (elektronik özellikler, elektron ilgisi, elektronegatiflik, moleküler sertlik ve yumuşaklık, elektrofilik indeks, kimyasal potansiyel gibi), moleküler yük dağılımı (Mulliken atomik yükleri), FT-IR spektrumları, moleküler elektrostatik potansiyel haritası (MEP), HOMO-LUMO enerjileri, dipol momentleri, toplam enerjileri ve elektronik yapı parametreleri hesaplanmıştır. Her iki yöntem için hesaplanan değerler karşılaştırılarak analiz edilmiştir.
Performatividad y roles de género en estudiantes universitarios. ¿Reconfiguración, cambio o simulación?
Authors: Urbiola Solís Alejandra Elizabeth , Cázares Garrido Ilia Violeta , Vázquez García Ángel Wilhelm
Published: November 2023

La pregunta central analizó la posible relación entre la enseñanza universitaria y el reconocimiento de las asimetrías de género entre mujeres y varones. La investigación se realizó con una muestra de 227 estudiantes universitarios entre los 18-30 años en una universidad pública mexicana del centro del país; se envió un cuestionario con quince preguntas y siete variables; posteriormente se analizaron las variables con mayor importancia: uso de espacios universitarios para discusión sobre estereotipos de género, lenguaje sexista, estereotipos de género, división de tareas domésticas, participación en colectivos de género y masculinidades, reflexión y evaluación personal en el tiempo y condición laboral. Se utilizó el software Qualitative Comparative Analysis (QCA). Los resultados mostraron que las variables más importantes para explicar el reconocimiento del sistema sexo-genérico entre los jóvenes universitarios, fueron los espacios universitarios, el lenguaje sexista, la división de tareas domésticas y la condición laboral en relación con la igualdad de oportunidades. El acceso y uso de los medios de comunicación no fue considerado relevante de acuerdo con los actores clave; otras variables importantes, pero no determinantes fueron la participación en colectivos de género y la reflexión y evaluación personal en el tiempo.
Numerical study of submerged hydraulic jumps over triangular macroroughnesses
Authors: Kumar Jayant Harshit , Jhamnani Bharat
Published: November 2023

The hydraulic jump is a phenomenon that occurs in open channels. In past studies, hydraulic jumps over smooth and macrorough beds have been investigated to enhance energy dissipation, but triangular macroroughness, specifically the right-angled triangular macroroughness, has not been dealt with. The objective of this article is to numerically investigate submerged hydraulic jumps over right angle and isosceles triangular macrorough beds. To achieve this, a numerical model based on computational fluid dynamics (CFD) has been utilized. Numerically obtained jump characteristics such as submerged depth ratio, tailwater depth ratio, longitudinal velocity profile, flow pattern in the cavity region, and energy dissipation have been presented in detail. In particular, initial Froude number reduction in both tailwater and submerged depth ratios as well as an increase in the energy dissipation of submerged hydraulic jumps have been noticed on isosceles triangular macroroughness with different arrangements, as compared to smooth beds. The present numerical model has been validated with the experimental model, and the mean error between the two for submerged depth and tailwater depth ratios was found to be below 6%. This confirms the adequacy of the present CFD model in predicting relevant submerged hydraulic jump characteristics over macrorough beds.
Spatiotemporal variability of vegetation response to meteorological drought on the Korean Peninsula
Authors: Jung Haeun , Won Jeongeun , Kang Shinuk , Kim Sangdan
Published: November 2023

To assess vegetation drought, it is important to understand the relationship between climate and vegetation and to accurately measure the response of vegetation activity to meteorological drought. In this study, we used the vegetation health index (VHI) to investigate the propagation time and time-lag of vegetation response to different meteorological drought indices, including the standardized precipitation index (SPI), evaporative demand drought index (EDDI), standardized precipitation–evapotranspiration index (SPEI), and copula-based joint drought index (CJDI). Using correlation analyses of meteorological drought indices with different time-scales and time-lags and VHIs with different weights, we determined which meteorological drought indices and their corresponding time-scales and time-lags best represent the effects of meteorological drought on vegetation activity on the Korean Peninsula. We also evaluated the relative roles of normalized difference vegetation index (NDVI) and land surface temperature (LST) in quantifying vegetation response to meteorological drought. The meteorological drought index for monitoring vegetation response to meteorological drought on the Korean Peninsula was best applied using EDDI in January–May and SPEI in June–December. Vegetation health was dominated by LST in January–September, with a higher impact of NDVI in November–December. We expect these results to provide useful information for vegetation drought monitoring.
Inflow and infiltration assessment of a prototype sanitary sewer network in a coastal city in China
Authors: Ye Licheng , Qian Yu , Zhu David Z. , Huang Biao
Published: November 2023

A 16-month monitoring program was conducted on a prototype sanitary system in a coastal city in China. The groundwater infiltration (GWI) on dry weather days and the rain-derived inflow and infiltration (RDII) on wet weather days were quantified and analyzed. The proportion of monthly averaged GWI to total flow can be as high as 70% during the observation period mainly due to the high groundwater level. The results also show that the ratio of RDII volume to total rainfall volume (defined as R-value) reaches a limited value of approximately 10% for the studied system when the total rainfall depth increases. A reference indicator Rlim for the limited R-value was proposed for assessing the conditions of sewer systems in terms of RDII. The Rlim value depends on local sewer conditions and in general, a lower Rlim value represents a better performance on RDII and vice versa. This study enriches the case studies on the performance of a specific sanitary sewer system on inflow and infiltration in a typical coastal city with exceptionally high groundwater levels, excess rainfall events in the monitoring season and possible typhoon events, which addresses the unique locational and hydrological properties of a representative coastal city.
Structure and Function of the SARS-CoV-2 6-HB Fusion Core and Peptide-Based Fusion Inhibitors: A Review
Authors: Liang Guodong , Li Yue , Li Ruijuan , Ma Yuheng , Na Heiya
Published: November 2023

SARS-CoV-2 has swept the world in recent years, triggering a global
COVID-19 with a tremendous impact on human health and public safety. Similar to
other coronaviruses, the six-helix bundle(6-HB) is not only a core structure driving the
fusion of the SARS-CoV-2 envelope with the host cell membrane, but also the target of
fusion inhibitors. The sequences from the HR1 or HR2 regions composing 6-HB are
thus the original primary structures for the development of peptide-based fusion inhibitors.
This review summarized the structure-activity relationship of the SARS-CoV-2 6-
HB, analyzed the design methods and functional characteristics of peptide-based fusion
inhibitors that contain different regions of HRs, and provided an outlook on the cutting-
edge approaches for optimal modification of lead compounds (pan-coronavirization,
chemical modification, superhelical construction, etc). We hope that this review will provide
researchers with a comprehensive understanding of the state-of-art research
progress on both 6-HB and peptide-based fusion inhibitors of SARS-CoV-2, and provide
some new insights for the development of antiviral drugs.
Potential Targets and Mechanisms of Bitter Almond-Licorice for COVID-19
Treatment Based on Network Pharmacology and Molecular Docking
Authors: Hong Qiwei , Shang Xinyue , Wu Yanan , Nie Zhenlin , He Bangshun
Published: November 2023

Background::

The outbreak of Corona Virus Disease 2019 (COVID-19) has resulted in millions of
infections and raised global attention. Bitter almonds and licorice are both Traditional Chinese Medicines
(TCM), often used in combination to treat lung diseases. Several prescriptions in the guidelines for the diagnosis
and treatment of coronavirus disease 2019 (trial version ninth) contained bitter almond-licorice, which was
effective in the treatment of COVID-19. However, the active ingredients, drug targets and therapeutic mechanisms
of bitter almonds-licorice for the treatment of COVID-19 remain to be elucidated.

Methods::

The active ingredients and targets were derived from the Traditional Chinese Medicine Systems
Pharmacology (TCMSP). Meanwhile, targets associated with COVID-19 were obtained from the GeneCards
database, PharmGkb database and DrugBank database. Then, the potential targets of bitter almond-licorice
against COVID-19 were screened out. Protein-protein interaction (PPI) networks and core targets were analyzed
through the String database and Cytoscape software. In addition, gene ontology (GO) and Kyoto Encyclopedia
of Genes and Genomes (KEGG) pathway enrichment analyses were performed based on potential targets
using R statistical software. Finally, molecular docking was used to validate the binding of the active ingredients
to the core targets.

Results::

The results of the TCMSP database showed that the bitter almond-licorice had 89 active components
against COVID-19, involving 102 targets. PPI network and core target analysis indicated that IL-6, TNF,
MAPK1, and IL1B were the key targets against COVID-19. In addition, GO and KEGG enrichment analysis
showed that the bitter almond-licorice were involved in various biological processes through inflammation-related
pathways such as TNF signaling pathway and IL-17 signaling pathway. Finally, molecular docking approaches
confirmed the affinity between the active components of the bitter almond-licorice and the therapeutic
targets.

Conclusion::

The bitter almond-licorice could be used to treat COVID-19 by inhibiting inflammatory responses
and regulating cellular stress. This work is based on data mining and molecular docking, and the findings
need to be interpreted with caution.
A Study and Analysis of Disease Identification using Genomic Sequence Processing Models: An Empirical Review
Authors: Ahuja Sony K. , Shrimankar Deepti D. , Durge Aditi R.
Published: November 2023

Human gene sequences are considered a primary source of comprehensive information about different body conditions. A wide variety of diseases including cancer, heart issues, brain issues, genetic issues, etc. can be pre-empted via efficient analysis of genomic sequences. Researchers have proposed different configurations of machine learning models for processing genomic sequences, and each of these models varies in terms of their performance & applicability characteristics. Models that use bioinspired optimizations are generally slower, but have superior incrementalperformance, while models that use one-shot learning achieve higher instantaneous accuracy but cannot be scaled for larger disease-sets. Due to such variations, it is difficult for genomic system designers to identify optimum models for their application-specific & performance-specific use cases. To overcome this issue, a detailed survey of different genomic processing models in terms of their functional nuances, application-specific advantages, deployment-specific limitations, and contextual future scopes is discussed in this text. Based on this discussion, researchers will be able to identify optimal models for their functional use cases. This text also compares the reviewed models in terms of their quantitative parameter sets, which include, the accuracy of classification, delay needed to classify large-length sequences, precision levels, scalability levels, and deployment cost, which will assist readers in selecting deployment-specific models for their contextual clinical scenarios. This text also evaluates a novel Genome Processing Efficiency Rank (GPER) for each of these models, which will allow readers to identify models with higher performance and low overheads under real-time scenarios.
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases
Authors: Patil Poonam , Doshi Gaurav
Published: November 2023

Pyroptosis has become a noteworthy area of focus in recent years due to its association
with inflammatory diseases. Pyroptosis is a type of programmed cell death accompanied by an inflammatory
response, and the discovery of the gasdermin family has expanded the study of pyroptosis.
The primary characteristics of pyroptosis include cell expansion, membrane penetration, and
the ejection of cell contents. In healthy physiology, pyroptosis is an essential part of the host's defence
against pathogen infection. Excessive Pyroptosis, however, can lead to unchecked and persistent
inflammatory responses, including the emergence of inflammatory diseases. More precisely,
gasdermin family members have a role in the creation of membrane holes during pyroptosis,
which leads to cell lysis. It is also related to how pro-inflammatory intracellular substances, including
IL-1, IL-18, and High mobility group box 1 (HMGB1), are used. Two different signalling pathways,
one of which is regulated by caspase-1 and the other by caspase-4/5/11, are the primary
causes of pyroptosis. Cardiovascular diseases are often associated with cell death and acute or
chronic inflammation, making this area of research particularly relevant. In this review, we first
systematically summarize recent findings related to Pyroptosis, exploring its characteristics and
the signalling pathway mechanisms, as well as various treatment strategies based on its modulation
that has emerged from the studies. Some of these strategies are currently undergoing clinical
trials. Additionally, the article elaborates on the scientific evidence indicating the role of Pyroptosis
in various cardiovascular diseases. As a whole, this should shed insight into future paths and
present innovative ideas for employing Pyroptosis as a strong disease-fighting weapon.
Prediction and Validation of Proline-containing Tripeptides with Angiotensin I-converting Enzyme Inhibitory Activity Using Machine Learning Models
Authors: Hatakenaka Toshiya , Fujimoto Yuki , Okamoto Kouji , Kato Tamaki
Published: November 2023

Background:

Numerous inhibitory peptides against angiotensin I-converting enzyme, a
target for hypertension treatment, have been found in previous studies. Recently, machine learning
screening has been employed to predict unidentified inhibitory peptides using a database of known
inhibitory peptides and descriptor data from docking simulations.

Objective:

The aim of this study is to focus on angiotensin I-converting enzyme inhibitory tripeptides
containing proline, to predict novel inhibitory peptides using the machine learning algorithm PyCaret
based on their IC50 and descriptors from docking simulations, and to validate the screening method
by machine learning by comparing the results with in vitro inhibitory activity studies.

Methods:

IC50 of known inhibitory peptides were collected from an online database, and descriptor
data were summarized by docking simulations. Candidate inhibitory peptides were predicted from
these data using the PyCaret. Candidate tripeptides were synthesized by solid-phase synthesis and
their inhibitory activity was measured in vitro.

Results:

Seven novel tripeptides were found from the peptides predicted to have high inhibitory activity by machine learning, and these peptides were synthesized and evaluated for inhibitory activity
in vitro. As a result, the proline-containing tripeptide MPA showed high inhibitory activity, with an
IC50 value of 8.6 µM.

Conclusion:

In this study, we identified a proline-containing tripeptide with high ACE inhibitory
activity among the candidates predicted by machine learning. This finding indicates that the method
of predicting by machine learning is promising for future inhibitory peptide screening efforts.
Isolation, Molecular Characterization, and Determination of Antibiotic Resistance
Patterns of Lactic Acid Bacteria from Regional Yogurt Samples
and their Probiotic Properties
Authors: Nahar Nazneen , Mahmud Shahin , Bin Islam Md. Shaid , Islam Safaiatul , Talukder Ashraf Hossain , Ali Talukder Kaisar , Mohiuddin A. K. M.
Published: November 2023

Objectives::

This investigation aims to isolate the Lactic Acid Bacteria (LAB) from yogurt
samples from the Tangail district of Bangladesh and evaluate their probiotic properties.

Methods::

A rigorous study was carried out from April to August, 2019. A total of 10 samples
were examined by following the standard bacteriological methods. Besides the biochemical and
antibiogram tests, molecular characterization of the isolated bacteria was carried out.

Results::

Ten isolates were confirmed as LAB, and they exhibited excellent probiotic properties.
They were able to survive in both acidic (pH 2) and alkaline (pH 8) conditions. They also survived
against phenol (0.1-0.4%) and NaCl (1-10%) after 24 h incubation. Most of the isolates harboured
plasmid DNA and showed good resistance patterns against the antibiotics used. During the
mating experiment, no X-conjugants were found.

Conclusion::

In conclusion, the mating experiment suggested that the acquired resistant genes
might be chromosome mediated, and isolates showed good probiotic properties that confer health
benefits.
Surgical and Orthodontic Management of Multiple Supernumerary Teeth Associated with Impacted Permanent Teeth: A Case Report
Authors: Alshammari Abdulrahman K. , Madfa Ahmed A.
Published: November 2023

Background:

Clinical problems are frequently detected when there are various irregularities in the number, structure, quantity, size, and eruption of the teeth. Supernumerary teeth can be found in almost any part of the dental arch, and because they are typically asymptomatic, they are frequently found by radiographic screening.

Case report:

The existence of the supernumerary teeth is the most frequent reason for impacted permanent teeth. This article describes the surgical and orthodontic treatment of a 20-year-old female with many supernumerary teeth and an impacted permanent tooth. All supernumerary teeth in the maxillary arch were extracted as part of the patient's treatment, and then the maxillary teeth were aligned using fixed appliances. The mandibular arch is left untreated, as the surgical removal of mandibular supernumerary teeth could damage the inferior alveolar nerve and result in numbness in the lower lip.

Conclusion:

In this case, we removed the extra teeth and used orthodontic traction to bring the remaining teeth into the proper position. After the procedure, the cosmetic outcome was greatly improved, and the patient's confidence increased.
Transalveolar Sinus Lift and Implant Site Preparation using Motorized Threaded Bone Expanders: A 2-year Retrospective Study
Authors: Albash Ziad , Khalil Ali
Published: November 2023

Background and Objectives:

The pneumatization of the maxillary sinus presents serious challenges to the dentist, and the management of such cases is essential for the rehabilitation of the posterior maxilla.

The aim of this study was to evaluate the clinical and radiographic outcomes of using motorized threaded bone expanders in transalveolar sinus lift procedures.

Materials and Methods:

This retrospective study was conducted on patients presented to the Department of Oral and Maxillofacial Surgery at Tishreen University who had transalveolar sinus lift using motorized threaded bone expanders with simultaneous dental implant placement between January, 2020, and August, 2022. The patients were followed up regularly for six months until loading. Statistical analyses were performed to assess intrasinus bone gain, marginal bone loss, implant diameter, and insertion torque. The correlation coefficient was used to measure the relationship between marginal bone loss and insertion torque value.

Results:

Three membrane perforations were observed in 34 procedures (8.82%). The survival rate for all implants was 100%. The main insertion torque was 32.58 N.cm. The mean intrasinus bone gain was 1.69 ± 0.44 mm. The mean marginal bone loss was 0.27 mm. The difference between IBH and bone height after 6 months showed a statistically significant difference. No correlation was found between marginal bone loss and insertion torque value.

Conclusion:

According to the results of this study, transalveolar sinus lift using motorized bone expanders showed effective lifting of the sinus floor with minimum marginal bone loss, thus presenting a good solution for pneumatization of the maxillary sinus to achieve a successful rate for implant placement.
Effects of an Individualized mHealth-Based Intervention on Health Behavior Change and Cardiovascular Risk Among People With Metabolic Syndrome Based on the Behavior Change Wheel: Quasi-Experimental Study
Authors: Chen Dandan , Zhang Hui , Wu Jingjie , Xue Erxu , Guo Pingping , Tang Leiwen , Shao Jing , Cui Nianqi , Wang Xiyi , Chen Liying , Ye Zhihong
Published: November 2023

Background

Metabolic syndrome (MetS) is a common public health challenge. Health-promoting behaviors such as diet and physical activity are central to preventing and controlling MetS. However, the adoption of diet and physical activity behaviors has always been challenging. An individualized mobile health (mHealth)–based intervention using the Behavior Change Wheel is promising in promoting health behavior change and reducing atherosclerotic cardiovascular disease (ASCVD) risk. However, the effects of this intervention are not well understood among people with MetS in mainland China.

Objective

We aimed to evaluate the effects of the individualized mHealth-based intervention using the Behavior Change Wheel on behavior change and ASCVD risk in people with MetS.

Methods

We conducted a quasi-experimental, nonrandomized study. Individuals with MetS were recruited from the health promotion center of a tertiary hospital in Zhejiang province, China. The study involved 138 adults with MetS, comprising a control group of 69 participants and an intervention group of 69 participants. All participants received health education regarding diet and physical activity. The intervention group additionally received a 12-week individualized intervention through a WeChat mini program and a telephone follow-up in the sixth week of the intervention. Primary outcomes included diet, physical activity behaviors, and ASCVD risk. Secondary outcomes included diet self-efficacy, physical activity self-efficacy, knowledge of MetS, quality of life, and the quality and efficiency of health management services. The Mann-Whitney U test and Wilcoxon signed rank test were primarily used for data analysis. Data analysis was conducted based on the intention-to-treat principle using SPSS (version 25.0; IBM Corp).

Results

Baseline characteristics did not differ between the 2 groups. Compared with the control group, participants in the intervention group showed statistically significant improvements in diet behavior, physical activity behavior, diet self-efficacy, physical activity self-efficacy, knowledge of MetS, physical health, and mental health after a 12-week intervention (P=.04, P=.001, P=.04, P=.04, P=.001, P=.04, P=.04, and P<.05). The intervention group demonstrated a statistically significant improvement in outcomes from pre- to postintervention evaluations (P<.001, P=.03, P<.001, P=.04, P<.001, P<.001, and P<.001). The intervention also led to enhanced health management services and quality.

Conclusions

The individualized mHealth-based intervention using the Behavior Change Wheel was effective in promoting diet and physical activity behaviors in patients with MetS. Nurses and other health care professionals may incorporate the intervention into their health promotion programs.
Reasons for Acceptance or Rejection of Online Record Access Among Patients Affected by a Severe Mental Illness: Mixed Methods Study
Authors: Schwarz Julian , Meier-Diedrich Eva , Neumann Katharina , Heinze Martin , Eisenmann Yvonne , Thoma Samuel
Published: November 2023

Background

Over the past few years, online record access (ORA) has been established through secure patient portals in various countries, allowing patients to access their health data, including clinical notes (“open notes”). Previous research indicates that ORA in mental health, particularly among patients with severe mental illness (SMI), has been rarely offered. Little is known about the expectations and motivations of patients with SMI when reading what their clinicians share via ORA.

Objective

The aim of this study is to explore the reasons why patients with SMI consider or reject ORA and whether sociodemographic characteristics may influence patient decisions.

Methods

ORA was offered to randomly selected patients at 3 university outpatient clinics in Brandenburg, Germany, which exclusively treat patients with SMI. Within the framework of a mixed methods evaluation, qualitative interviews were conducted with patients who chose to participate in ORA and those who declined, aiming to explore the underlying reasons for their decisions. The interviews were transcribed and analyzed using thematic analysis. Sociodemographic characteristics of patients were examined using descriptive statistics to identify predictors of acceptance or rejection of ORA.

Results

Out of 103 included patients, 58% (n=60) wished to read their clinical notes. The reasons varied, ranging from a desire to engage more actively in their treatment to critically monitoring it and using the accessible data for third-party purposes. Conversely, 42% (n=43) chose not to use ORA, voicing concerns about possibly harming the trustful relationship with their clinicians as well as potential personal distress or uncertainty arising from reading the notes. Practical barriers such as a lack of digital literacy or suspected difficult-to-understand medical language were also named as contributing factors. Correlation analysis revealed that the majority of patients with depressive disorder desired to read the clinical notes (P<.001), while individuals with psychotic disorders showed a higher tendency to decline ORA (P<.05). No significant group differences were observed for other patient groups or characteristics.

Conclusions

The adoption of ORA is influenced by a wide range of motivational factors, while patients also present a similar variety of reasons for declining its use. The results emphasize the urgent need for knowledge and patient education regarding factors that may hinder the decision to use ORA, including its practical usage, its application possibilities, and concerns related to data privacy. Further research is needed to explore approaches for adequately preparing individuals with SMI to transition from their inherent interest to active engagement with ORA.

Trial Registration

German Clinical Trial Register DRKS00030188; https://drks.de/search/en/trial/DRKS00030188
Meaningful Social Inclusion and Mental Well-Being Among Autistic Adolescents and Emerging Adults: Protocol for a Community-Based Mixed Methods Study
Authors: McMaughan Darcy Jones , Lewis Casey , McGehee Amy , Noreen Dani , Parker Elliot , Criss Michael M
Published: November 2023

Background

In the United States, autistic people face high rates of co-occurring mental illnesses and premature death due to self-harm, which are indicators of threats to mental well-being. Social inclusion may enhance mental well-being and resilience among autistic people. According to Simplican and colleague’s (2015) model of social inclusion for people with intellectual and developmental disabilities, social inclusion is an interaction between community participation and interpersonal relationships. There is limited research on social inclusion that includes the integration of interpersonal relationships and community participation among autistic people or the impact of social inclusion on the well-being of autistic people. Additionally, little evidence exists regarding how autistic people prefer to be included in the community or form interpersonal relationships.

Objective

The long-term objective of this project is to improve social inclusion factors to support the mental well-being of autistic people. This protocol describes a community-based, mixed methods pilot study to develop a definition of meaningful social inclusion for autistic people and to understand the relationship between meaningful social inclusion and mental well-being among autistic adolescents and emerging adults.

Methods

The project uses a community-based, sequential mixed methods design with a formative phase (Phase 1) that informs a survey phase (Phase 2) and concludes with a process evaluation of the community engagement process (Phase 3). During Phase 1, we will recruit 10 community partners (autistic adults and stakeholders) and conduct sharing sessions to cocreate a definition of meaningful social inclusion and a survey of meaningful social inclusion and well-being. During Phase 2, we will recruit 200 participants (100 autistic adolescents and emerging adults and 100 caregivers) to complete the survey. We will examine whether meaningful social inclusion predicts well-being given sociodemographic factors using ordered logistic regression, with well-being categorized as low, medium, and high. During Phase 3, the community partners from Phase 1 will complete a survey on their experiences with the project.

Results

Ethics approval was obtained for this project in March 2023. We have recruited community partners and started the Phase 1 focus groups as of September 2023. Phase 2 and Phase 3 have not yet started. We expect to complete this study by March 2025.

Conclusions

Using a community-based, mixed methods approach, we intended to develop a definition of meaningful social inclusion for autistic people and understand the role meaningful social inclusion plays in the well-being of autistic people.

International Registered Report Identifier (IRRID)

PRR1-10.2196/52658
Internet Addiction, Anxiety Levels, and Salivary Cortisol among Medical Students in the North of Iran (Preprint)
Authors: Shahini Sr Najmeh , hashemifar aida , salehi Mohammad , kashani Leila , derakhshanpour firoozeh
Published: November 2023

BACKGROUND

Contrary to the positive uses of the internet, the existence of extreme behaviors and their harmful effects, especially Internet addiction (IA) among students, has attracted researchers' attention.

OBJECTIVE

This study aimed to investigate the relationship between Internet addiction (IA) and anxiety levels and salivary cortisol levels in medical students

METHODS

This descriptive, analytical, cross-sectional study was performed on 110 medical students (intern) of Golestan University of Medical Sciences, Gorgan, Iran. The demographic information was collected using a checklist. The Young's Internet Addiction Test (IAT) was used to measure Internet addiction and the Hamilton Anxiety Rating Scale (HAM-A) was used to measure anxiety levels. In addition, a sample of saliva was collected in the early morning to investigate the relationship between salivary cortisol levels and IA.

RESULTS

The mean age of the subjects was 24.69 years (±SD 1.18). The salivary cortisol level of the subjects was 5.57 µg/dl (±SD 3.20). The IAT score for IA was significantly higher in the male than in the female group (50.42 (±SD 24.11) vs. 41.09 (±SD 22.36), respectively, P = 0.008). 54 (49.1%), 34 (30.9%), and 22 (20%) students were classified as mild, moderate, and severe Internet addiction. There is no association between IA and salivary cortisol levels (P = 0.377). The Hamilton test score for anxiety was not significantly different between male and female groups (29.22 (±SD 10.95) vs 28.05 (±SD 12.02), respectively, P = 0.682). Anxiety scores for mild, moderate, and severe IA categories showed a statistically significant difference (P = 0.035). There is no association between anxiety and salivary cortisol levels (P = 0.86).

CONCLUSIONS

The prevalence of severe Internet addiction among medical students is close to 20%. The findings of the study showed a statistical relationship between the severity of Internet addiction and higher levels of anxiety disorders, however, there is no association between IA and salivary cortisol levels.
Digital Twins Prevalence in the Medical Fields: A Bibliomatrics Study and Visualization Analysis via CiteSpace (Preprint)
Authors: Zhou TingTing
Published: November 2023

BACKGROUND

Digital twins have their origins in NASA's space craft production and have lately gained popularity in the medical field. They are derived from computer simulations of virtual things and possess distinct traits and uniformity. Currently, it is extensively utilized in several surgical procedures as well as in gene identification and prognosis. The integration of digital twins and medicine is now uncertain, although it is worth exploring extensively.

OBJECTIVE

We will be doing an academic research using the visualization tool CiteSpace to investigate the explicit connection between digital twins and the field of medicine. Additionally, we want to suggest ethical considerations related to this topic.

METHODS

Using the CiteSpace 5.75r version, we retrieved data from the WOS Core Collection and PubMed. We then analyzed this data to create a network of countries, institutions, and co-occurring keywords. Additionally, we identified keywords with citation bursts and conducted timeline and cluster analysis. Through the use of tables and figures, we demonstrated the hot spots and trends of digital twins in medicine.

RESULTS

Encompassing 1015 research, the data reveals a significant surge in the yearly number of publications. The tree map showcases the primary study subject as Health Care Science Service, and presents a visual analysis of the top 10 countries, institutions, co-occurrence keywords, burst words, clusters, and timeline.

CONCLUSIONS

Visualization analysis may definitively corroborate the results and clearly demonstrate the evolution of digital twins technology in medicine. It also offers additional references for researchers in the same field. Nevertheless, the practical application of digital twins in a therapeutic setting will necessitate the resolution of a diverse array of technological, medical, ethical, and theoretical challenges.
Equations of a Synchronous Machine in Phase Coordinates for Asymmetrical Short Circuits and their Solutions
Authors: Guliyev Huseyngulu , Ibrahimov Famil
Published: November 2023

A methodology is proposed for studying, using digital technology, asymmetrical transient modes of a synchronous generator operating on infinite power systems. The initial equations of a synchronous machine and sequential transformations for their solution are presented. Differential equations of synchronous machines are compiled in phase coordinates. When solving the equations, the parameters of the electrical network included between the generator and the system are taken into account. The results of calculations using the obtained equations for the 14-node IEEE test circuit are presented, confirming the effectiveness of this approach.
Exploring the Intersection of Caste and Gender Politics in Kusumabale
Authors: Sangeeta Dr
Published: November 2023

This research delves into the intricate interplay of caste and gender politics within the narrative of Kusumabale By closely examining the novel's portrayal of characters, events, and societal dynamics, the study aims to unravel the complex web of relationships shaped by both caste and gender influences. Through a nuanced analysis, the research explores how caste identities intersect with gender roles, impacting the lives and struggles of characters in the narrative. Additionally, the study investigates the ways in which the author, Devanoor Mahadeva, navigates and challenges traditional norms through the lens of caste and gender, contributing to a deeper understanding of societal structures within the context of the novel. This exploration not only sheds light on the intricacies of caste and gender politics in Kusumabale but also provides broader insights into the complex dynamics of identity and power within contemporary literature.
A Modern Critique of Orientalism in Contemporary Visual Art
Authors: Shi Emma
Published: November 2023

Orientalism is historically understood as a cultural phenomenon of 18th and 19th century Europe, when Western artists emulated Asian culture and aesthetics in their work. In 1979, Edward Said’s Orientalism first introduced a post-colonial critical analysis to the European, Western portrayal of Eastern cultures in the Middle East. In spite of the perceived progress since the publication of Said’s book, the underlying principles of Said’s Orientalism critique are still widely applicable to modern visual art in 2023. This study is a fresh look at the persistence of Orientalism in contemporary Asian art. Research will show that Orientalism is not just a historical phenomenon, but an ongoing unsavory, and harmful reality in today’s art world. Using data and examples collected from contemporary sources, I will examine and analyze the artwork of visual artists and art institutions in Western countries that reflect Orientalism in their portrayal of Chinese and East Asian cultures.
Люминесцентная нанотермометрия с одиночными органическими молекулами: влияние электрон-­фононного взаимодействия
Authors: Савостьянов А.О. , Еремчев И.Ю. , Наумов А.В.
Published: November 2023

Московский педагогический государственный университет (МПГУ), Москва, Россия
Люминесцентная термометрия – ​стремительно развивающийся научный метод, основанный на зависимости люминесцентных и спектральных характеристик наноразмерных излучателей от температуры. Точность данного метода существенным образом зависит от используемых теоретических моделей, описывающих температурное поведение спектров. В настоящей работе мы приводим краткий обзор наших недавних результатов, связанных с новыми подходами к описанию температурного уширения спектральных линий одиночных органических молекул в полимерной матрице как результата электрон-­фононного взаимодействия. Мы полагаем, что рассматриваемый подход может быть успешно применен для разнообразных перспективных излучателей, используемых в люминесцентной термометрии.
Phytochemical Analysis and Antibacterial Potential of Stevia rebaudiana (Bertoni, 1899) Leaf Extracts against Aeromonas Species: Influence of Extraction Methods and Solvents in Aquaculture Applications
Authors: Raghu Ashitha , Velayudhannair Krishnakumar
Published: November 2023

Recent studies have explored Stevia rebaudiana Bertoni leaf extracts for their antibacterial potential and phytochemical content. However, the impact of extraction methods and solvents on aquaculture bacteria remains understudied. This research aimed to evaluate the antibacterial, radical scavenging, and phytochemical properties of S. rebaudiana extracts against Aeromonas species. Dried S. rebaudiana leaves were extracted using methanol (Mt) and ethanol (Et) through Soxhlet and maceration methods (SMt, SEt, MMt and MEt respectively). Soxhlet extraction yielded higher amounts (36.29% for Mt, 23.87% for Et) compared to maceration. Phytochemical analysis identified phenolics, flavonoids, alkaloids, saponin, tannin, and steroids in all extracts. Notably, MEt had elevated phenolic and flavonoid content, while SEt contained more tannins. MEt exhibited the strongest antioxidant activity (IC50 = 67.95µg/mL), aligning with its high phenolic and flavonoid levels. In antibacterial assays against Aeromonas strains, ethanol extract showed the largest zone of inhibition (ZOI) of 16.67mm for A. salmonicida, followed by methanol extract (15mm) at 250 mg/mL, using maceration and Soxhlet methods, respectively. However, none of the extracts displayed activity against A. hydrophila. This suggests that cold maceration is a cost-effective method that preserves heat-sensitive secondary metabolites within a shorter extraction time. In conclusion, this study highlights the significance of extraction techniques and solvents in obtaining potent antibacterial and antioxidant extracts from S. rebaudiana leaves. The findings emphasize the potential of these extracts in aquaculture practices and open avenues for further research in utilizing natural compounds for sustainable aquaculture strategies.