bluuebunny/crossref_metadata_2025 huggingface dataset:
Emissões Otoacústicas Evocadas Transientes em Neonatos a Termo e Pré-Termo na Presença e na Ausência de Sucção
Authors: Amorim Filgueira Raquel , Saccardo Sarni Roseli
Published: October 2020

Objetivo: Verificar se os ruí­dos provocados pelo mecanismo de sucção/deglutição interferem nas EOAETs em neonatos a termo e pré-termo. Método: estudo realizado com 40 neonatos (27 nascidos a termo e 13 pré-termo), avaliados com presença de EOAETs, em repouso e em situação de sucção. Resultados: Analisando a ocorrência de EOAETs no momento sem sucção/deglutição em comparação com o momento sucção/deglutição, segundo a freqüência, constatou-se que em 2000 Hz ocorre maior número de falhas durante a sucção. Conclusão: Não houve variação estatisticamente significante entre os resultados obtidos sem sucção e em sucção nutritiva no seio materno, tal achado possibilita que o exame pode ser realizado das duas formas sem prejuí­zo nos resultados
Efeitos de intervenção educativa no conhecimento de escolares sobre aleitamento materno
Authors: Kayny da Silva Leão Mí­ria , De Sousa Franco Maurilo , De Barros Sousa Gyzelda , De Sousa Nobre Roseanne , Santos do Vale Hiugo , De Oliveira Lima Luisa Helena
Published: October 2020

Objetivo: Comparar o conhecimento de escolares sobre aleitamento materno, antes e após intervenção educativa. Método: estudo comparativo, transversal, com abordagem quantitativa, realizado no perí­odo de março a outubro de 2018 em escolas públicas municipais em um municí­pio piauiense com 24 escolares de 7 a 9 anos. Nesse estudo, foi realizado um pré-teste que avaliou o conhecimento de escolares, uma intervenção educativa com uso da história em quadrinhos impressa e jogo educativo. Após intervenção, aplicou-se pós-teste seguindo-se de análise comparativa do conhecimento em relação ao aleitamento materno. Resultados: do total de entrevistados no pré-teste, 12 obtiveram conhecimento insuficiente, 3 obtiveram bom conhecimento e nenhum alcançou o conhecimento ótimo. Após a intervenção educativa, constatou-se que nenhum escolar obteve conhecimento insuficiente e 19 escolares foram classificados com conhecimento bom. Conclusão: Foi possí­vel observar uma melhora nos ní­veis de conhecimento após a intervenção educativa.
Enhancement of Medical Image Fusion Using Image Processing
Authors: Dr. U. Palani  , D. Vasanthi  , S. Rabiya Begam
Published: October 2020

The assortment of all indispensable data from at least two pictures and the principle incorporation is partitioned into less picture pixels as a rule into an individual one to build the norm of the picture and diminish the iterative so as to improve all the fundamental uses of clinical picture which is utilized to investigate all the clinical issues. This cycle is called as Clinical picture mixture. The parceling by watershed calculation for these sub-pictures are standard to get the areas of individual level, these districts are utilized to manage the combination cycle. To keep up the basic enumerations, the watershed calculation is accustomed to achieving the picture division.
IMPLEMENTATION OF INNOVATIVE FORMS AND MODELS OF PUBLIC ADMINISTRATION IN THE SPHERE OF CULTURE IN UKRAINE
Authors:   Vasyl Stefanyk Precarpathian National University, Karpa Marta , Akimov Oleksandr ,   Interregional Academy of Personnel Management, Shykerynets Vasyl ,   Vasyl Stefanyk Precarpathian National University
Published: October 2020

The article examines the actual problem of the development of the sphere of culture in Ukraine. Today, with the arrival and development of the state and civil society in Ukraine, a new model of state policy is being formed, which requires further improvement of the quality of public administration in the field of culture, its formation, style, methods and legal forms based on modern research. In these conditions, the main task of the functioning of public authorities and management of the sphere of culture, the latter must be solved in cooperation with state institutions, cultural intelligentsia and outstanding cultural figures, is to improve the principles and directions of culture, state policy, which is of great strategic importance for countries to develop and modernize. The aim of the article: to investigate the peculiarities of the implementation of innovative forms and models of state policy in the field of culture in Ukraine, using the best European experience in public administration in the field of culture. The research methodology: to solve the set research tasks, the following methods of cognition were used in the work: analysis and synthesis - to substantiate the need and disclose the essence of the implementation of state policy in the field of culture, as well as to examine the modern legal and regulatory framework of Ukraine, regulating the functioning of this area; structural and functional - to study the organizational structure of authorities in the sphere of culture; comparative analysis - to compare the characteristics of the cultural policy of Spain, Italy, France and Germany. The subject of the research is the peculiarities of the implementation of innovative forms and models of state policy in the field of culture in Ukraine, with the possibility of implementing the best European experience. Therefore, the article actively used the analysis to compare the characteristics of the cultural policy of Spain, Italy, France and Germany. As a result of the study, conclusions were drawn regarding the possible use of diversification of the mechanism for financing the sphere of culture in Ukraine; the creation of cultural centers should be funded by government grants; the creation in Ukraine of functional and regulatory provisions obliging the authorities at the regional and local levels to involve leaders on the basis of an open competition and training in the field of cultural management to create opportunities for the cultural and social development of the state.
DEVELOPMENT OF PRIVATE EDUCATION IN UKRAINE: SECOND HALF OF XIX-EARLY XX CENTURY
Authors:   Volodymyr Vynnychenko Central Ukrainian State Pedagogical University, Akimkin Olexandr
Published: October 2020

The article reveals the leading factors in the development of private education in Ukraine in the second half of the XIX - early XX century. It was found that the second half of XIX - early XX century becomes a period not only of social, scientific, national revival, but also a period of rapid development of private education. The purpose of the article is to reveal the leading factors in the development of private education in Ukraine in the second half of the XIX - early XX century. The historical-logical method made it possible to determine the socio-political and social features of social development and their impact on the development of private education in Ukraine in this historical period; constructive-genetic method made it possible to determine the socio-historical and cultural-pedagogical prerequisites for the development of private education in Ukraine in the second half of the XIX - early XX century and others. The leading area of implementation of pedagogical innovations in this period was a private school, which was explained by the strict legal regulation of the state educational system and at the same time the lack of real steps by the government to modernize it. The key innovations of the pedagogical concept in the innovative activities of a private institution were: the priority of the pupil's personality, the integration of family and school, increasing the requirements for the teacher, who must act as the personification of an active and creative personality. It is established that the leading factors in the development of private education in Ukraine in the second half of the XIX - early XX century were: the presence of legislative regulation of private education; establishment of public-state character of organizational bases of their activity; manifestation of public initiative in the opening of private educational institutions; taking into account in the organizational and substantive aspects of the activities of private schools the social and economic needs of the country's development.
UKRAINIAN AIRCRAFT CONSTRUCTION AS THE PRECONDITION OF EMERGENCE OF DOMESTIC AVIATION EDUCATION
Authors:   Volodymyr Vynnychenko Central Ukrainian State Pedagogical University, Necheporuk Yana
Published: October 2020

The historical preconditions for the emergence of the domestic system of civil aviation flight training in Ukraine were its active actions in the process of the development of aviation and aircraft construction. The particular aim of this article is to study the historic development of Kyiv Polytechnic Institute, to find out how it became the cradle of Ukrainian aviation and plane construction, to highlight and characterize the key persons who influenced the development of the domestic aircraft industry, to give the comparative characteristics to old educational and modern principles of aircraft constructors training. To solve the tasks of the article, a set of research methods was used, due to its subject, goals and objectives: comparative analysis (theoretical analysis, synthesis, generalization, systematization of scientific sources, periodicals to solve this problem and clarify the conceptual apparatus of the study); chronological and diachronic (determination the development and essential changes in preparing the aircraft construction personnel in KPI); search and bibliographic (systematization and classification of pedagogical, methodical, scientific literature, archival materials, periodicals on the aeronautical achievements in Kyiv Polytechnic Institute); comparative and historical (analysis and comparison of socio-pedagogical phenomena that make it possible to identify positive inputs in Ukrainian aviation industry). Comparing educational methods at the beginning of the XX century and the beginning of the XXI century, it should be noted that now in addition to generating talented ideas the student should have many professional competencies. In addition to strict requirements for future specialists, the state also makes certain requirements for higher education institutions that train future aircraft designers.
MORPHOMETRIC AND HISTOCHEMICAL CHARACTERISTICS OF THE CRIBRIFORM TYPE OF INTRADUCTAL CARCINOMA OF THE MAMMARY GLAND
Authors: Nikolenko Dmytro Y. , Boiko Dmytro M. , Shkurupii Olexandr A. , Ovcharenko Oksana V.
Published: October 2020

Introduction: Due to the increasing morbidity and mortality rates from breast cancer, the problem of early, especially morphological diagnosis, continues to be important. The aim of this study to investigate the karyometric and histochemical features of cribriform pattern of parenchyma of intraductal carcinoma of the mammary gland. Materials and methods: Operational and biopsy material was studied in form of serial sections of micropreparations of cribriform type intraductal carcinoma of the mammary gland. Fixation with 10% neutral formalin, paraffin sections are stained with hematoxylin and eosin, complex Bergman + Periodic Acid - Schiff (PAS) reaction + alcyan blue. Cariometry was performed on 100 parenchymal tumor cell, tenth logarithms of the nucleus volume (LgV) were determined, kariocavirogram was constructed. Results: The atypical cellular polymorphism of the tumor, cribriform structures with cancerous cells in the state of apoptosis was revealed. The modal nuclear classes are defined in the interval LgV 0,75; 0,9; 1,2; 1,45, and do not comply with the law of rhythmic growth of nuclei in normal and confirm the cellular atypism of a cancerous tumor. Results are deprived of subjectivity through mathematical analysis of data in percentages (%). Histochemically, in the cytoplasm of cancer cells, precursors of lipids were detected in the form of a Schiff (PAS) positive reaction; alcyan-positive basal membrane of the duct; Bergman-positive protein structures in the nuclei. Conclusions: Cariometry and histochemical analysis of intraductal carcinoma of the mammary gland is an objective and accessible complex method for the analysis of atypical cells, reveals the degree of differentiation, apoptosis of cells and non-invasive stage of cancer.
SURGICAL SITE INFECTIONS AND ANTIMICROBIAL RESISTANCE IN KYIV CITY HOSPITALS, UKRAINE
Authors: Salmanov Aidyn G. , Dyndar Olena A. , Vdovychenko Yuriy P. , Nykoniuk Tetiana R. , Maidannyk Igor V. , Chorna Olena O. , Holovanova Iryna А.
Published: October 2020

Introduction: Surgical site infections (SSIs) are associated with increased morbidity and mortality. Scant information is available on the SSI in Ukrainian hospitals.
The aim: to determine the incidence of SSIs and estimates antimicrobial resistance of the major responsible pathogens in Kyiv city hospitals.
Materials and methods: This study was conducted from January 2011 to December 2013 in 3 hospitals. Definitions of SSIs were adapted from the CDC/NHSN. The identification
and antimicrobial susceptibility of cultures were determined, using automated microbiology analyzer. Some antimicrobial susceptibility test used Kirby - Bauer antibiotic testing.
Results: Among 9,162 patients, 1,912 (20.9%) SSIs were observed. The high SSI case in appendectomy (29.8 %), gastric, small and large bowel surgeries (28.4 %), cholelithiasis
(25.7%), and orthopedic procedures (22.9 %). Low infection rate in excision of dermoid cysts, lipoma (5.3%) and lower segment caesarean structure (6.5%). Staphylococcus
aureus were most commonly reported, accounting for 27,8% of all organisms, followed by Escherichia coli (18.4 %), Pseudomonas aeruginosa (11.9 %) and Enterococcus faecalis
(11.6 %). The antimicrobial resistance in the isolates associated with SSIs showed, among the Gram-positive bacteria, that 43.8% and 4.7% of CoNS isolates were β-lactam
(oxacillin) - and glycopeptide (teicoplanin) - resistant, respectively. Meticillin resistance was reported in 35.7 % of S. aureus isolates
Conclusions: SSIs and antimicrobial resistance of the responsible pathogens is an actually problem. One essential step in the prevention of SSIs is to implement a national
system for their surveillance.
PREDICTION OF RISK IN DEPENDENCE FROM DISEASE AND WORKING CONDITIONS OF EMPLOYEES WHICH EMPLOYED IN EXTRACTION OF IRON ORE
Authors: Oriekhova Oksana V. , Pavlenko Oleksandr I.
Published: October 2020

Introduction: The assessment and management of occupational risks has the purpose conducting of analysis and assessing the health of workers by timely, complete and adequate passing of the previous and periodic medical examination, registration and analysis of morbidity and establishment of cause-and-effect relationship with working conditions. The aim:Prediction of occupational risk based on study of diseases with temporary disability was conducted in the analysis of disability sheets and the report on causes of temporary disability in workers extraction of iron ore. Materials and methods: Hygienic, epidemiological and statistical methods of research were used to solve this purpose. Results: In the workers involved in the extraction and processing of iron ore the level of morbidity with temporary disability is from 81,87±3,64 to 98,06±2,49 cases (p<0,05), from 806,53±40,51 to 1217,67±63,50 days of disability (p<0,05), the average duration of one case was from 10,00±1,42 to 12,39±0,24, and according to the scale of assessment of the indicators of morbidity rates by L. E. Notkin characterized in days as average; in cases as high. The calculation of morbidity rates (L and OR) makes it possible to predict what degree and class of harmful production factors can lead to the corresponding levels of morbidity. The proposed forecasting method makes it possible to predict the categories of occupational risk in depending on the class of working conditions and the relative risk of morbidity with temporary disability. Conclusions: Studying the morbidity and condition of working conditions is the basis for predicting occupational risk for effective management decisions.
TEN INDICATORS WHICH CHARACTERIZE MEDICAL-DEMOGRAPHIC PROCESSES IN ADJACENT REGIONS OF UKRAINE AND POLAND
Authors: Grshybowskyj Jaroslaw L. , Smiianov Vladyslav A. , Myronyuk Ivan M. , Lyubinets Oleh V.
Published: October 2020

Introduction: Medical-demographic processes are one of the main signs of life quality, the level of socio-economic development of society.
The aim of the work is to compare and evaluate the medical-demographic processes in the two neighboring regions of neighboring countries, due to their geographical proximity, the ratio of the size of the territories and the population.
Materials and methods: The study was conducted on the basis of official statistics published by the State Statistics Service of Ukraine and the Main Department of Statistics in Poland, the depth of the research - 2008-2017, the scope of the study - Lviv region of Ukraine and the Podkarpackie region of Poland. The system approach, demographicand medical-statistical methods were used in the work.
Review: In both territories the population aging is going on, illustrated by indicators such as the age structure of the population, the level of demographic load and the
average age of the population. Data on population reproduction in both regions is narrowed, indicating a prevalence of mortality over births. The average life expectancy in the Podkarpackie region is higher and has a tendency for further growth. In the Lviv oblast, the average life expectancy is also growing, due to the positive trend towards a decrease
in overall mortality, but is offset by a decline in fertility and high infant mortality and mortality rates, especially from circulatory system pathology.
Conclusions: The analysis of our 10 indicators showed the heterogeneity of medical and demographic processes in the two neighboring regions of neighboring countries,
despite their geographical proximity, the ratio of the size of the territories and the population.
KEY WORDS: medical-demographic processes, population.
Wiad Lek 2019, 72, 5 cz. I, -
ANALYSIS OF INDICATORS OF THE ORTHOPEDIC CAREPROVISION TO THE ADULT POPULATION OF UKRAINE DURING 2012-2017
Authors: Hermanchuk Serhii M. , Struk Volodymyr I. , Bida Vitaliy І. , Bida Alexander V.
Published: October 2020

Introduction: Despite the development of dental science and the introduction of modern methods of treatment of dental diseases into practice that allow solving the most difficult clinical situations, the level of dental morbidity remains high. The decrease in the level of dental health negatively affects the state of general somatic health, causing social maladaptation, which in general is negatively reflected at the level of country’s socio-economic development.
The aim of our research is a comparative analysis of the provision of orthopedic care to the adult population of Ukraine on the basis of officially published statistical data of
the Ministry of Health of Ukraine.
Materials and methods: For the analysis, the officially published statistical data of the Ministry of Health of Ukraine and the Centre for Medical Statistics of the Ministry of
Health of Ukraine have been selected.
Conclusions: A comparative analysis of the provision of orthopaedic dental care to the adult population of Ukraine has shown a change in the quantitative indicators of
manufactured orthopaedic constructions both by years and by regions. Coordination of dental care and the introduction of an effective system of monitoring the state of dental health in all parts of the medical and diagnostic process and the necessary forms of statistical reporting will contribute to the creation of an effective system for assessing the quality of dental care.
PATHOGENETIC PECULIARITIES OF NEUROENDOCRINE AND METABOLIC DISORDERS IN PATIENTS WITH ACNE ASSOCIATED WITH CHRONIC STRESS
Authors: Dashko Marianna O. , Syzon Orysya O. , Chaplyk-Chyzho Iryna O. , Turkevych Solomiya A.
Published: October 2020

Introduction: Acne is a chronic relapsing skin condition with multifactorial nature associated with disorders of sebaceous glands activity, psycho-emotional disorders and slow response to treatment. The aim: To study a pathogenic role of chronic stress and certain metabolic and neuroendocrine disorders in the development of acne in women depending on the duration of the disease. Materials and methods: A total of 119 women with acne were examined. Index insulin resistance (іndex HOMA), serum cortisol and prolactin, level of Reactivity-Personal Anxiety and Dermatology Life Quality Index (DLQI) was determined. Results: Possible changes in serum cortisol level depending on duration of the disease (increased in women with duration of the disease less than 1 year and decreased in women with duration of the disease 1-5 years), increased index of serum prolactin and HOMA, with more significant changes in women with duration of the disease 1-5 years. The DLQI was determined in all examined patients. An increased level of anxiety, characterized by higher levels of personal anxiety, was also observed, especially in a group of women with duration of the disease 1-5 years. Conclusion: The changes in certain neuroendocrine and metabolic indices, which are the markers of chronic stress, worsening of life quality and significant levels of reactivity and personal anxiety, were observed in women with acne. A strong and moderate correlational relationship between the nature of changes in the abovementioned indices and duration of the disease was detected.
IMMUNOGLOBULIN INDICATORS TO VIRUSES CYTOMEGAL AND GENITAL HERPES IN THE BLOOD SERUM OF WOMEN WITH NON-ATIPICAL ENDOMETRIAL HYPERPROLIFETATIVE PATHOLOGY
Authors: Gorban Nataliia E. , Vovk Irina B. , Nikitina Iryna M. , Kondratiuk Valentina K. , Yemets Nadiia O.
Published: October 2020

The aim of the study was to analyze the level of Ig M- and Ig G-antibody (Ab) for cytomegalovirus (CMV) and herpes simplex virus type 2 (HSV-2) in serum of women with
non-atypical endometrial hyperproliferative pathology.
Materials and methods: The analysis of immunoglobulin indices to CMV and HSV-2 in serum of women with non-atypical endometrial hyperproliferative pathology. In women
with uterine body polyps the presence of CMV in the uterine cavity was found in 54.8% of cases, in women with non-atypical endometrial hyperplasia in 38.3% of cases. The
levels of Ig G-Ab and Ig M-Ab to CMV in serum have a clear dependence on the degree of antigen expression in endometrial tissue. HSV-2 antigens were determined in 22.58
± 5.31% of women with uterine body polyps and in 8.33 ± 3.57% of patients with non-atypical endometrial hyperplasia while increasing serum specific antibodies to HSV-2.
Results: The results indicate that there is a clear link between viral infection of hyperproliferatively altered endometrium and the determination of positive immunoglobulin levels in peripheral blood, which may be a reliable marker of chronic persistent viral infection in a woman’s body.
Conclusions: In women with uterine body polyps, the presence of CMV in the uterine cavity was found in 54.84 ± 6.32% of cases, in women with non-atypical endometrial
hyperplasia in 38.33 ± 6.28% of cases. The levels of Ig G-Ab and and Ig M-Ab to CMV in serum have a clear dependence on the degree of antigen expression in endometrial
tissue. HSV-2 antigens were determined in 22.58 ± 5.31% of women with uterine body polyps and in 8.33 ± 3.57% of patients with non-atypical endometrial hyperplasia while
increasing serum specific antibodies to HSV-2. The results indicate that there is a clear link between viral infection of the target tissue (hyperproliferatively altered endometrium) and the determination of a positive level of peripheral blood immunoglobulin, which may be a reliable marker of chronic persistent viral infection in a woman.
RELATIONSHIP BETWEEN INTERLEUKIN-6 GENE POLYMORPHISM AND HEART FAILURE IN PATIENTS WITH CORONARY ARTERY DISEASE AND OBESITY
Authors: Kravchun Pavlo G. , Kadykova Olga I. , Ryndina Natalia G. , Krapivko Svitlana O. , Kozhyn Mykhailo I. , Zolotaikina Victoriia I.
Published: October 2020

The aim: To examine the association between polymorphisms of the IL-6 gene promoter and HF in patients with CAD and obesity.
Material and methods: 222 patients with coronary artery disease and obesity were identified. Comparison group consisted of 115 patients with coronary artery disease with normal body weight. The groups were comparable in age and sex. The exclusion group consisted of patients with severe concomitant diseases of the respiratory and digestive organs, kidneys and people with cancer. One single nucleotide polymorphisms in the interleukin-6 promoter region was analyzed. Odds ratio (OR) and 95 % confident interval (95 % CI) were calculated.
Results: The combined course of coronary artery disease and obesity was characterized by the detection of allele C in 62 patients (27.93 %), allele G – in 160 patients (72.07 %), and genotypes CC, CG and GG – at 24 (10.81 %), 67 (30.18 %) and 131 (59.01 %) patients respectively. The results showed that the −174G allele and GG genotype in patients with coronary artery disease and obesity were associated with heart failure (OR = 2.55, 95% CI = [1.72-3.79], χ2 = 22.8; p<0.05) and (OR = 11.95, 95% CI = [3.41-41.91], χ2 = 22.5; p<0.05), whereas allele C−174 was associated with a decrease in the risk of heart failure (OR = 0.39, 95% CI = [0.26-0.58 ], χ2 = 22.75, p<0.05).
Conclusions: The obtained results testify that the −174G>C polymorphism in the interleukin-6 gene is significantly associated with increased risk of heart failure in patients with coronary artery disease and obesity.
QUALITY OF LIFE OF PATIENTS RECEIVING HOME-BASED PALLIATIVE CARE FROM FAMILY PHYSICIANS AND MOBILE PALLIATIVE CARE TEAM
Authors: Detsyk Oryna Z. , Bratsyun Oleksandra P. , Babich Раvlo M.
Published: October 2020

The aim: To evaluate the quality of life (QoL) of palliative patients receiving general palliative care and the impact of palliative care provided by mobile palliative care team
(MPCT) on their QoL.
Materials and methods: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core30 (QLQ-C30) was used to evaluate QoL of 219 palliative patients receiving general palliative care from family physicians in the Center for primary health care of Uzhhorod city, Ukraine. In the second part of the study, the subgroup of 25 patients who had at least one of fifteen QLQ-C30 scales evaluated lower than 50 points were selected. They were provided with PC from the MPCT for 2 weeks and their QoL was measured again.
Results: For the patients who received general palliative care from a family physicians mean m (SD) QoL value was 38.63 (16.9), and the main symptoms that affected QoL were fatigue 48.60 (23.30) and pain 46.11 (20.97). The most impact on QoL scores had role (rs=0,430;), emotional (0.321) and physical (0.301) functioning and such symptoms as pain (-0.392), insomnia (-0.311), dyspnoea (-0.294), financial difficulties (-0.255). For the patients who received palliative care from MPCT mean the mean QoL score increased by 30.0 points, mean pain score decreased by 42.22 points, fatigue score decreased by 38.0 points and level of financial difficulties also decreased by 76.0 points.
Conclusions: The involvement of the MPCT could have a significant positive impact on the QoL of palliative patients.
ABNORMAL UTERINE BLEEDING IN ADOLESCENTS: CURRENT STATE OF THE PROBLEM
Authors: Tuchkina Iryna O. , Vygivska Liudmyla A. , Novikova Anastasia A.
Published: October 2020

The aim: To summarize the literature data on abnormal uterine bleeding in adolescents. Materials and methods: This article presents an assessment of 32 literary sources from 2003 to 2018, which raise the issues of etiology and pathogenesis of abnormal uterine bleeding in adolescents. Abnormal uterine bleeding in adolescents (AUBA) is a risk factor for disorders of menstrual and generative function, hormone-related abnormalities in the reproductive age. Despite the progress made in the development of methods for the diagnosis and treatment of AUBA, the criteria for selecting a particular method of diagnosis and therapy have not yet been made sufficiently clear. Conclusions: AUBA is a complex polyetiological disease affecting all parts of the hypothalamic-pituitary-adrenal-ovarian system. It has a negative impact on the girl’s health and quality of life. Abnormal uterine bleeding is a “signal” to the body of an organic or functional disorder. If this feature is ignored, the pathology can progress and lead to severeconsequences. The urgency of the problem of AUBA is further explained by the fact that this disease indicates the presence of serious disorder of the reproductive system, which in the future may be transformed into impaired reproductive function.
THE EVOLUTION OF TREATMENT AT THE ORTHOPEDICS AND REHABILITATION CLINIC
Authors: Niezbecka-Zając Joanna , Turżańska Karolina , Posturzyńska Agnieszka , Horecka Anna
Published: October 2020

Introduction: The last 20 years have been a period of huge changes in Polish healthcare, both in terms of medical progress as well as organization and financing. These changes,
and especially the newly introduced queuing systems significantly influenced the changes in the profile of hospital admission.
The aim: To analyze changes in the patient profile, causes and time of hospitalization, as well as the waiting time for hospitalization, in 1996-2019 Lublin SPSK4 Orthopedics
and Rehabilitation Clinic.
Material and methods: Patients’ medical records were analyzed, including qualification cards. The waiting time for admission to the hospital, the time of hospitalization, the
cause of hospitalization, gender and the patient’s place of residence were analyzed.
Results and conclusions: 1. During the 13 years analyzed, the number of hospitalizations increased from 452 to 1387 patients a year. 2. The waiting time for hospitalization increased from an average of 2 months in 1996 to even 2 years (in the case of patients with chronic category) in 2020. 3. The average length of hospitalization changed compared to the level of 1996 (8 weeks) in the case of patients with the early neurological category increased slightly (9 weeks), in the case of other patients - it decreased to 4 weeks, respectively - chronically ill patients, 3 weeks - patients from the systemic and weekly rehabilitation category - orthopedic patients. 4. The scope of the reasons for hospitalization, but also methods of treatment has expanded significantly. 5. Patient demographic profile in the examined aspects (origin, gender) - remained similar.
DISORDERS OF THE INTESTINAL FLORA AND IT IS EFFECT ON SKELETAL SYSTEM DISEASES
Authors: Tomczyk-Warunek Agnieszka , Dubiel Anna , Poleszak Ewa , Blicharski Rudolf , Dobrzyński Maciej
Published: October 2020

The intestinal microflora plays an important role in the proper functioning of human. It is complex, diverse and dynamic ecosystem that constantly strives to maintain homeostasis throughout the body. The process of acquiring intestinal microflora begins immediately after human birth. Elementary factors that determine the modification of the composition of the microflora are age, sex, diet, lifestyle. Determinate individual composition of the microflora. Microorganisms inhabiting the intestine perform various functions, from metabolic, immune to trophic. Early changes in the intestinal microflora are reflected in the state of human health. Recently, many studies have been carried out confirming the hypothesis that the bacterial flora of the gastrointestinal tract affects the normal metabolism of bone tissue, and disorders in its composition can lead to the appearance of bumps in the processes of physiological remodeling of bone tissue and contribute to the formation of many inflammations. Microorganisms that rot in the digestive tract regulate bone metabolism through three mechanisms: the impact on the immune system, the hormonal system and the impact on the absorption of minerals. Disorders in the microflora of the digestive tract can lead to the development of inflammatory bowel diseases, and as a consequence to the accelerated development of osteoporosis or arthrosis of the joints.
The aim: To collect available publications confirming the impact of microflora on the skeletal system.
HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN PREGNANT AND POSTPARTUM WOMEN
Authors: Obuchowska Aleksandra , Kamiński Maciej , Kimber-Trojnar Żaneta , Grzesik Paulina , Standyło Arkadiusz , Turżańska Karolina , Leszczyńka-Gorzelak Bożena
Published: October 2020

Introduction: Haemophagocytic lymphohistiocytosis (HLH) is an extremely rare, life-threatening disease, caused by uncontrolled activation of lymphocytes T and macrophages.
This situation leads to cytokine storm, infiltration and internal organs failure. HLH can be categorised into either primary (familiar) or secondary which may be associated with infections, immunodeficiency syndromes, autoimmune diseases and malignancy. The secondary HLH is difficult to diagnose due to nonspecific symptoms and complicated differential diagnostics.
The aim: To conduct a comparative analysis of pregnant and puerperal patients diagnosed with HLH.
Material and methods: Review of available literature on haemophagocytic lymphohistiocytosis during pregnancy and the puerperium
Results: Review of the latest literature shows that HLH can occur at any time during pregnancy and in the puerperium. Symptoms of the disease are non-specific: fever not
responding to antibiotic therapy, sometimes hectic, hepatosplenomegaly, swelling, lymphadenopathy, disseminated intravascular coagulation, multi-organ failure and death. In laboratory tests, worsening bicytopenia or pancytopenia, increasing indicators of organ damage, hypertriglyceridemia, hypofibrinogenemia and abnormally high serum ferritin levels are observed.
Conclusions: HLH, due to non-specific symptoms and rarity, is often overlooked in the diagnostic process. Due to the high mortality and morbidity rates of HLH during pregnancy for mother and foetus, timely diagnosis and the inclusion of specialist treatment are particularly important. An interdisciplinary approach to the patient is necessary to make an accurate diagnosis. The assessment of serum ferritin concentrations facilitates diagnosis. The bone marrow is essential to diagnosis and should be performed as early as possible.
DYSPHAGIA IN NEUROLOGICAL DISORDERS
Authors: Śledzik Amelia , Szlendak Paweł
Published: October 2020

Introduction: Neurogenic dysphagia is a frequent disorder affecting people with neurological diseases. Many experts work together to diagnose and treat dysphagia.
The aim: The article focuses on the specificity of neurogenic dysphagia, its symptoms and treatment possibilities. The speech pathologist can be included in the diagnostic
process and can evaluate the intake of liquids and foods based on a variety of consistency tests. In clinical conditions, screening tests such as water swallowing test, multiple consistency tests: GUSS (Gugging Swallowing Screen), V-VST (Volume-Viscosity Swallow Test) and EAT-10 questionnaire can be used successfully. If you have limited ability to perform instrumental tests, they can help you to expand your diagnosis.
Review and Discussion:Treatment of swallowing disorders is based on a daily modification of the patient’s posture and consistency of the eaten meals. Nursing staff are involved in this adaptation activity, which plays an invaluable role in the diagnosis and treatment of patients in neurological and rehabilitation departments.
Conclusions: Despite the knowledge of the problem, difficulty swallowing is still unnoticed. The effects of this neglect are felt both for patients and from the perspective of management within treatment units For people suffering from neurological diseases, swallowing disorders should be diagnosed on a compulsory basis and their assessment should be a permanent part of the standard procedures for assessing patients with neurological deficits.
TOTAL SHOULDER ARTHROPLASTY, AN OVERVIEW, INDICATINS AND PROSTHETIC OPTIONS
Authors: Wicha Mateusz , Tomczyk-Warunek Agnieszka , Jarecki Jaromir , Dubiel Anna
Published: October 2020

Shoulder arthroplasty (SA) has improved significantly over the last twenty years. It offers the effective treatment for patients with severe shoulder dysfunctions. The indications for this procedure have recently expanded tremendously. However, the most common are glenohumeral osteoarthritis, inflammatory shoulder arthropathies, rotator cuff-tear arthropathy, complex fractures of the proximal humerus and osteonecrosis of a humeral head. There is range of the procedures, such as resurfacing of humeral head, anatomic total shoulder arthroplasty, hemiarthroplasty and reverse shoulder arthroplasty. All of them could significantly improve patients quality of life. The outcomes of the shoulder arthroplasty are very satisfying in terms of pain relief and considerable improvements in shoulder function as well as in motion. However, this procedure is not so popular as knee or hip arthroplasties. The reasons for this phenomenon are not clear. The complication rate is considerably low. The most common are periprosthetic fractures, infections,
implant loosening and instability. The reasonable solution is a conversion to reverse total shoulder arthroplasty. The survivorship of the prosthesis is up to 12 years, which is acceptable by patients. Long term result are still not clear. Surgeons performing SA opt for deltopectoral approach which provides good exposure of the joint also for revisions.
The aim: To summarize knowledge about SA based on current literature.
Recent evidence on visual-spatial ability in surgical education: A scoping review
Authors: Kalun Portia , Dunn Krista , Wagner Natalie , Pulakunta Thejodhar , Sonnadara Ranil
Published: October 2020

Background: Understanding the relationships between structures is critical for surgical trainees. However, the heterogeneity of the literature on visual-spatial ability (VSA) in surgery makes it challenging for educators to make informed decisions on incorporating VSA into their programs. We conducted a scoping review of the literature on VSA in surgery to provide a map of the literature and identify where gaps still exist for future research.

Methods: We searched databases until December 2019 using keywords related to VSA and surgery. The resulting articles were independently screened by two researchers for inclusion in our review.

Results: We included 117 articles in the final review. Fifty-nine articles reported significant correlations between VSA tests and surgical performance, and this association is supported by neuroimaging studies. However, it remains unclear whether VSA should be incorporated into trainee selection and whether there is a benefit of three-dimensional (3D) over two-dimensional (2D) training.

Conclusions: It appears that VSA correlates with surgical performance in the simulated environment, particularly for novice learners. Based on our findings, we make suggestions for how surgical educators may use VSA to support novice learners. Further research should determine whether VSA remains correlated to surgical performance when trainees move into the operative environment.
ALIANZAS MULTI-ACTOR Y TRANSFORMACIÓN: EL CASO DE LA ALIANZA SHIRE
Authors: Mendoza Dalia
Published: October 2020

La Agenda 2030 y los Objetivos de Desarrollo Sostenible (ODS) plantean la posibilidad de apuntar hacia la transformación mediante la creación y el fortalecimiento de alianzas multi-actor. La colaboración entre sector público, sector privado, ONGs y universidad, y su interacción con otros actores propicia un ambiente de innovación hacia la búsqueda de soluciones que contribuyan a los ODS. La Alianza Shire, la primera alianza multi-actor para la acción humanitaria en España, tiene como objetivo desarrollar soluciones innovadoras de acceso a la energía en los campos de refugiados y sus comunidades de acogida del norte de Etiopía. En este artículo se presenta la Alianza Shire como experiencia demostradora de alianzas multi-actor que aspiran a la transformación. Su formación, la implementación de un proyecto piloto, el escalado hacia una segunda fase, y el planteamiento de siguientes pasos incluyen una serie de aspectos transformadores que aseguran la creación de un valor compartido de colaboración para lograr un cambio sistémico significativo.
ODS3+: DEL CONCEPTO A LA IMPLEMENTACIÓN DE LA “SALUD EN TODAS LAS POLÍTICAS” EN ESPAÑA
Authors: Ramírez-Rubio Oriana , Carrasco José Miguel , González-Rubio Raquel , Fanjul Gonzalo
Published: October 2020

La Agenda 2030 cuenta con un Objetivo de Desarrollo Sostenible (ODS) específico relacionado con la salud y el bienestar, el ODS3, que aspira a garantizar una vida sana y a promover el bienestar para todas las personas. El enfoque de salud en todas las políticas propuesto por la Organización Mundial de la Salud (OMS), insta a considerar las repercusiones de las políticas públicas en la salud de la población, evidenciando que ODS diferentes al ODS3 también están relacionadas con ella. Se propone, por tanto, un abordaje amplio y transversal de la salud dentro de la Agenda 2030, que denominamos ODS3+.
Desde este enfoque, y tras un proceso participativo, se identifican 6 dimensiones en las que España debería centrar sus esfuerzos para mejorar la salud de su población: género, determinantes sociales, determinantes medioambientales y cambio climático, enfermedades no transmisibles y salud mental, sistema sanitario y social y la dimensión global de la salud y la cooperación internacional; aunque tras la aparición de la pandemia por COVID-19 se propone reconsiderar las enfermedades infecciosas emergentes. Analizados los indicadores relativos a las metas ODS de dichas dimensiones, se identifican áreas de mejora a las que
atender durante la próxima década en este país, siendo imprescindible adoptar un enfoque transversal que considere el impacto en la salud de todas las políticas, en todos los sectores y en todas las acciones.
Silvering (slowly)
Authors: Douglas Carl , Gallagher Sue , O'Hara Emily , Patel Rafik , Tapuni Nooroa
Published: October 2020

‘Silvering (slowly)’ was a group show at St Paul Street Gallery in Auckland, NZ, 9–13 September 2019. It drew together threads from our independent research trajectories as a response to this journal’s questions around augmentation and technicity. The exhibition was a material dialogue consisting of installations and drawings, structured dialogues before and during the show, and an epistolary exchange afterwards. 
The operative methodology is one of conversation between collaborators that was conceived more generally as an open-ended material practice including nonhuman participants. Without purporting to offer a single consistent position, we problematise the concept of augmentation through our conversation. By means of our rhetorical figures—the moon, mirrors, silvering hair, and silence—we question the time and matter of augmentation, and its sense of forwardness and addition.
On Fractional Fragility Rates of Graph Classes
Authors: Dvořák Zdeněk , Sereni Jean-Sébastien
Published: October 2020

We consider, for every positive integer $a$, probability distributions on subsets of vertices of a graph with the property that every vertex belongs to the random set sampled from this distribution with probability at most $1/a$. Among other results, we prove that for every positive integer $a$ and every planar graph $G$, there exists such a probability distribution with the additional property that for any set $X$ in the support of the distribution, the graph $G-X$ has component-size at most $(\Delta(G)-1)^{a+O(\sqrt{a})}$, or treedepth at most $O(a^3\log_2(a))$. We also provide nearly-matching lower bounds.
Physical Properties, Pasting Characteristics and Rheological Behaviour of Paddy Varieties Suitable for Flaking
Authors: Dhritiman Saha  , Arun Kumar T V  , Swati Sethi  , Indore Navnath
Published: October 2020

A study was conducted to find the effect of moisture content on various physical properties of paddy varieties (MTU-1010 and BB-11) suitable for flaking. The range of moisture studied was 11.11% to 28.2% (d.b.) for both the paddy varieties. The bulk density of the paddy increased from 514.76 kg/m3 to 563.62 kg/m3 for MTU-1010 variety and 605.28 kg/m3 to 632.62 kg/m3 for BB-11 variety respectively when the moisture content was increased in the experimental range. The sphericity increased from 0.386 to 0.399 for MTU-1010 variety and 0.448 to 0.458 for BB-11 variety with increase in moisture content. The true density and porosity decreased with the increase in moisture content of paddy. The other physical properties such as test weight, surface area, arithmetic mean diameter, geometric mean diameter and angle of repose increased with the increase in moisture content of paddy. The static coefficient of friction of paddy increased with the increase in moisture content on different surfaces e.g. wood, mild steel, and galvanized iron. The regression equations for all the response variables were significant at P < 0.05 with coefficient of determination, R2 (> 0.90). The amylose content in MTU-1010 and BB-11 variety was found to be 30.23% and 26.32% respectively indicating that high amylose containing paddy varieties are generally used for flaking paddy. Further, the pasting properties of both the paddy varieties revealed higher pasting temperature in paddy variety MTU-1010 than BB-11. The rheological studies highlighted higher storage modulus of brown rice than the polished rice for both the paddy varieties.
“Vede”, “olhai”: o sentido da visão na lírica camoniana
Authors: Cattapan Julio
Published: October 2020

Análise da função do sentido da visão na lírica camoniana à luz do conceito de heroico furor, de Giordano Bruno, com ênfase na estrita relação entre amor, imagem e visão. O amor heroico como impulsionador de uma busca interminável por um conhecimento superior em que os contrários se harmonizem numa síntese e a multiplicidade das coisas do mundo possa ser integrada numa unidade, o que permitiria alcançar um saber total de ordem divina. O amor sensível como um meio para o conhecimento, e o olhar como condição necessária para esse amor.
Note Design Of Khorezm Makoms And Mutual Integration Of Music With Fine Arts
Authors:   Professor, Department Of Music Education, Urgench State University, Urgench, Uzbekistan, Khudaibergenov Samandar Kuzievich , Khaitbaev Diyarbek Janibekovich ,   Senior Lecturer, Department Of Fine Arts And Engineering Graphics, Urgench State University, Urgench, Uzbekistan
Published: October 2020

The paper is dealing with fret construction of Khorezmian makoms and its common structure Comparative analysis of Bukharian and Khorezmian makoms had been made. The conclusion about main styles of makoms are given also.
PENERAPAN MODEL PEMBELAJARAN INKUIRI UNTUK MENINGKATKAN HASIL BELAJAR SISWA PEMULA PADA PELAJARAN TEMATIK
Authors: Tsalitsatul Maulidah  , Sukiyanto
Published: October 2020

This study aims to determine the application of inquiry learning models, student learning outcomes in Thematic subjects the objects around us to beginner students in class V. This research is a type of quantitative analysis using designs in the form of one group pretest and posttest. The study population was all fifth-grade elementary school students, amounting to 23 students' data collection techniques using the method of observation and learning outcomes tests. The instrument to measure learning outcomes using pretest and posttest in the form of objective analysis is multiple choice. Data were analyzed using hypothesis testing with the help of the product-moment formula and Paired Sample t-test. The results of this study indicate that learning using inquiry learning models is shown by the average feasibility of aspects with a range of values ​​of 3.50-3.88. And there is an influence of the inquiry learning model on student learning outcomes in Thematic learning the themes of objects around us in class V, as evidenced by the testing of hypotheses obtained r count = 0.806 and r tables = 0.433. While the Paired Sample t-test significance test, showed a correlation before and after the inquiry learning model was applied at 0.806> α (0.05). Based on the values, it can be concluded that the inquiry learning model has a positive influence on student learning outcomes in Thematic learning of the objects around us in the fifth grade of significantly.