bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Validation of a High-Throughput Quantification Method of Crown Procyanidins in Different Wines by UHPLC-Q-TOF
Authors: Ferreira Manon , Teissedre Pierre-Louis , Jourdes Michaël
Published: January 2025

Procyanidins are widely distributed in plant-derived foods, and consist of flavanol oligomers and polymers. Recently, the crown procyanidin sub-family, characterised by a unique macrocyclic structure, has been identified in grapes and wine. This study reports the development and validation of a rapid and quantitative analytical method measuring crown procyanidin concentration in red and white wines using ultra-high-performance liquid chromatography (UHPLC) coupled with a Q-TOF mass spectrometer. Validation followed international standards, demonstrating high sensitivity (LOQ = 0.033 mg/L), accuracy (recovery = 88.21% to 107.64%), repeatability (RSD = 1.99% to 11.03%), and intermediate reproducibility (RSD = 2.51% to 19.05%). Minimal matrix effects were observed, ensuring reliable and precise quantification across both wine types. The applicability of the method was confirmed through the successful analysis of wine samples, leading to the first quantification of crown procyanidins in white wine. Concentrations ranged from 0.81 mg/L to 15.88 mg/L in the different analysed wines. This validated method provides a valuable tool for the study of crown procyanidin profiles in various wine matrices and establishes a foundation for future research into the role of crown procyanidins in wines and other food and beverage matrices where these compounds may be present.
Cu0-Functionalized, ZIF-8-Derived, Nitrogen-Doped Carbon Composites for Efficient Iodine Elimination in Solution
Authors: Chen Jiuyu , Gao Chensheng , Chen Jingwen , Liu Fei , Liu Zhiwen
Published: January 2025

The development of copper-based materials with a high efficiency and low cost is desirable for use in iodine (I2) remediation. Herein, Cu0-nanoparticles-functionalized, ZIF-8 (Zeolite Imidazole Framework-8)-derived, nitrogen-doped carbon composites (Cu@Zn-NC) were synthesized by ball milling and pyrolysis processes. The as-prepared composites were characterized using SEM, BET, XRD, XPS, and FT-IR analyses. The results showed that the morphology of ZIF-8 changed from a leaf-like structure into an irregular structure after the introduction of a copper salt and carbonization. The copper in the pyrolysis samples was mainly in the form of Cu0 particles. The presence of an appropriate amount of Cu0 particles could increase the specific surface area of Cu@Zn-NC. The subsequent batch adsorption results demonstrated that the as-fabricated composites showed high I2 adsorption amounts (1204.9 mg/g) and relatively fast dynamics in an iodine–cyclohexane solution when the Cu content was 30% and the pyrolysis temperature was 600 °C, outperforming the other Cu-based materials. The isothermal adsorption followed both Langmuir and Dubinin–Radushkevich isotherm models, while the kinetics of I2 adsorption followed a pseudo-second-order kinetic model. The activation energy (Eα) of the adsorbent was determined to be 47.2 kJ/mol, according to the Arrhenius equation. According to the experimental and DFT analyses, I2-Zn interactions and I2-Cu0 chemisorption jointly promoted the elimination of iodine. In general, this study provided an operative adsorbent for the highly effective capture of iodine in solution, which might be worth applying on a large scale.
MoS2–Plasmonic Hybrid Platforms: Next-Generation Tools for Biological Applications
Authors: Moussa Nayra A. M. , Lee Seungah , Kang Seong Ho
Published: January 2025

The combination of molybdenum disulfide (MoS2) with plasmonic nanomaterials has opened up new possibilities in biological applications by combining MoS2’s biocompatibility and high surface area with the optical sensitivity of plasmonic metals. These MoS2–plasmonic hybrid systems hold great promise in areas such as biosensing, bioimaging, and phototherapy, where their complementary properties facilitate improved detection, real-time visualization, and targeted therapeutic interventions. MoS2’s adjustable optical features, combined with the plasmon resonance of noble metals such as gold and silver, enhance signal amplification, enabling detailed imaging and selective photothermal or photodynamic therapies while minimizing effects on healthy tissue. This review explores various synthesis strategies for MoS2–plasmonic hybrids, including seed-mediated growth, in situ deposition, and heterojunction formation, which enable tailored configurations optimized for specific biological applications. The primary focus areas include highly sensitive biosensors for detecting cancer and infectious disease biomarkers, high-resolution imaging of cellular dynamics, and the development of phototherapy methods that allow for accurate tumor ablation through light-induced thermal and reactive oxygen species generation. Despite the promising advancements of MoS2–plasmonic hybrids, translating these platforms into clinical practice requires overcoming considerable challenges, such as synthesis reproducibility, toxicity, stability in physiological conditions, targeted delivery, and scalable manufacturing. Addressing these challenges is essential for realizing their potential as next-generation tools in diagnostics and targeted therapies.
Clinical Outcome After Surgical Treatment of Traumatic Peroneal Nerve Injury: An Analysis of Risk Factors After Different Surgical Approaches
Authors: Werkmann Daniel N. , Bäzner Ute M. , Petkov Martin , Minzenmay Lena , Durner Gregor , Antoniadis Gregor , Wirtz Christian R. , Pedro Maria T. , Knoll Andreas , Pala Andrej
Published: January 2025

Background: This study aims to analyze potential risk factors that may influence the clinical outcomes following surgical treatment of traumatic peroneal nerve lesions. Methods: We conducted a retrospective analysis of patients with traumatic peroneal nerve injuries treated with decompression, split repair, or nerve grafting between 2010 and 2020. Motor function and potential risk factors were evaluated. Results: Out of 93 patients, 42 (45%) underwent decompression, 15 (16%) received split repair, and 36 (39%) required autologous nerve grafting. Up to one year after surgery, weakness of the anterior tibial muscle improved from a median of M0 to M3. After one year following nerve decompression, functional recovery was observed in 28 (65%) cases, in 9 (21%) cases after split repair, and in 7 (16%) cases following autologous nerve grafting. A defect greater than 8 cm was associated with significantly poorer improvement of extensor hallucis longus (p = 0.037, HR 0.109). We found no significant associations between age, diabetes mellitus, arterial hypertension, obesity, and postoperative outcomes. Conclusions: According to the present data, a significant number of patients achieved functional improvement following surgical treatment, indicating that this procedure should be considered an important treatment option in selected cases.
Sleep Quality, Nutritional Habits, and Physical Activity in Pediatric Cancer Survivors: A Dyadic Analysis Approach
Authors: Serpas Dylan G. , Sauls Rachel , Gray Heewon L. , Stern Marilyn
Published: January 2025

Background/Objectives: Sleep disturbances are prevalent among pediatric cancer survivors (PCSs) and their caregivers, often leading to poorer dietary choices and reduced physical activity. Additionally, the sleep quality and health behaviors of parents and children can affect each other. This study examined bi-directional associations between PCSs and their parents’ sleep quality and health-related behaviors. Methods: 127 parent–child dyads enrolled in a behavioral intervention for pediatric cancer survivors (Mage = 11.04; 53.2% female) and their families completed the Patient Sleep Quality Inventory (PSQI) and USDA Parent or Child Food and Activity Questionnaire (FAQ). Two actor–partner interdependence models, using multi-level modeling and adjusting for relevant confounds, estimated the bidirectional associations between the parent–child dyad’s sleep quality and composite food and physical activity quality. Results: After controlling for partner BMI and actor and partner age, the effect of children’s PSQI scores on parent’s FAQ scores was statistically significant (β = −0.23, p = 0.036). Poorer sleep quality in children was associated with worse physical activity and dietary behaviors in parents. Second, after adjusting for race, a significant partner effect for parents’ FAQ scores on children’s PSQI scores was shown—greater parental food and physical activity quality was associated with better sleep quality in PCS (β = −0.20, p = 0.041). Conclusions: Better food and activity quality for parents is linked to improved sleep quality for children, while children’s poor sleep quality is associated with lower food and activity quality in parents. The findings highlight the prospective value of systems-focused clinical interventions to manage sleep quality and promote positive health behaviors among PCS.
Relationship Between Depression and Epigallocatechin Gallate from the Perspective of Gut Microbiota: A Systematic Review
Authors: Zhang Yangbo , Liu Changwei , Zhu Qi , Wu Hui , Liu Zhonghua , Zeng Li
Published: January 2025

Depression, a serious mental illness, is characterized by high risk, high incidence, persistence, and tendency to relapse, posing a significant burden on global health. The connection between depression and gut microbiota is an emerging field of study in psychiatry and neuroscience. Understanding the gut–brain axis is pivotal for understanding the pathogenesis and treatment of depression. Gut microbes influence depression-like behaviors by impacting the hypothalamic–pituitary–adrenal axis (HPA), monoamine neurotransmitters, immune responses, cell signaling, and metabolic pathways. Tea, widely used in clinical practice to improve neuropsychiatric disorders, contains Epigallocatechin gallate (EGCG), a major ingredient of green tea, which effectively regulates intestinal flora. This review examined the risks and causes of depression, the complications associated with intestinal flora, their role in the development and treatment of depression, and how EGCG may alleviate depression through interactions with gut microbiota and other mechanisms.
Effects of Protein Intake on Cognitive Function in Chinese Older Adults: A 10-Year Follow-Up Study
Authors: Zheng Ting , Zheng Xiao , Xiao Shujuan , Xue Benli , Chen Chengyu , Li Yuyang , Li Xiyan , Zhang Chichen
Published: January 2025

Background: As the global population ages, there is an increasing prevalence of mild cognitive impairment and dementia. Protecting and preserving cognitive function in older adults has become a critical public health concern. Methods: This study utilized data from four phases of the Chinese Longitudinal Healthy Longevity Survey conducted from 2008 to 2018, encompassing a total of 2454 participants. Latent growth curve modeling was employed to analyze the trajectory and role of protein intake frequency and cognitive function. Results: The frequency of protein intake among older adults tends to rise, with individuals exhibiting higher initial levels experiencing smaller subsequent increases. Conversely, cognitive function generally declines, with those starting at higher levels experiencing more pronounced decreases. Notably, the initial frequency of protein intake is positively correlated with the initial level of cognitive function (β = 0.227, 95% CI: 0.156 to 0.299, p < 0.001), but does not significantly influence the rate of change in cognitive function (β = −0.030, 95% CI: −0.068 to 0.009, p = 0.128). The rate of change in protein intake frequency is positively associated with the rate of change in cognitive function (β = 0.152, 95% CI: 0.023 to 0.280, p = 0.020). Conclusions: The alterations in protein intake frequency are linked to alterations in cognitive function among older adults. Maintaining a stable high frequency of protein intake or increasing the frequency of protein intake may contribute to stabilizing cognitive function as well as reducing the risk of cognitive impairment and dementia in older adults.
Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus
Authors: Martiniakova Monika , Sarocka Anna , Penzes Noemi , Biro Roman , Kovacova Veronika , Mondockova Vladimira , Sevcikova Aneta , Ciernikova Sona , Omelka Radoslav
Published: January 2025

Type 2 diabetes mellitus (T2DM), a serious metabolic disorder, is a worldwide health problem due to the alarming rise in prevalence and elevated morbidity and mortality. Chronic hyperglycemia, insulin resistance, and ineffective insulin effect and secretion are hallmarks of T2DM, leading to many serious secondary complications. These include, in particular, cardiovascular disorders, diabetic neuropathy, nephropathy and retinopathy, diabetic foot, osteoporosis, liver damage, susceptibility to infections and some cancers. Polyphenols such as flavonoids, phenolic acids, stilbenes, tannins, and lignans constitute an extensive and heterogeneous group of phytochemicals in fresh fruits, vegetables and their products. Various in vitro studies, animal model studies and available clinical trials revealed that flavonoids (e.g., quercetin, kaempferol, rutin, epicatechin, genistein, daidzein, anthocyanins), phenolic acids (e.g., chlorogenic, caffeic, ellagic, gallic acids, curcumin), stilbenes (e.g., resveratrol), tannins (e.g., procyanidin B2, seaweed phlorotannins), lignans (e.g., pinoresinol) have the ability to lower hyperglycemia, enhance insulin sensitivity and improve insulin secretion, scavenge reactive oxygen species, reduce chronic inflammation, modulate gut microbiota, and alleviate secondary complications of T2DM. The interaction between polyphenols and conventional antidiabetic drugs offers a promising strategy in the management and treatment of T2DM, especially in advanced disease stages. Synergistic effects of polyphenols with antidiabetic drugs have been documented, but also antagonistic interactions that may impair drug efficacy. Therefore, additional research is required to clarify mutual interactions in order to use the knowledge in clinical applications. Nevertheless, dietary polyphenols can be successfully applied as part of supportive treatment for T2DM, as they reduce both obvious clinical symptoms and secondary complications.
A Four-Year Study of Antibiotic Resistance, Prevalence and Biofilm-Forming Ability of Uropathogens Isolated from Community- and Hospital-Acquired Urinary Tract Infections in Southern Italy
Authors: Trinchera Marilena , Midiri Angelina , Mancuso Giuseppe , Lagrotteria Maria Antonietta , De Ani Carmelo Antonio , Biondo Carmelo
Published: January 2025

The aim of this study was to investigate the differences between nosocomial and community microorganisms isolated from patients with UTI by determining their bacterial profile, antibiotic resistance and ability to produce biofilms. A retrospective study, based on bacterial isolates from consecutive urine samples collected between January 2019 and December 2023, was conducted at a university hospital. The main pathogens isolated from both community and hospital samples were the same, but their frequency of isolation differed. Compared with community-associated cases, hospital-associated infections have more isolates of Acinetobacter baumanii complex. In contrast, Proteus mirabilis isolates were more prevalent in community than in hospital infections. In both hospital and community isolates, gram-positive bacteria showed a lower overall antimicrobial resistance (22%) compared to gram-negative bacteria (30%). The data demonstrated that individual strains exhibited disparate degrees of capacity for biofilm formation. Additionally, the data indicate an inverse correlation between biofilm production and antibiotic resistance. Isolates from community patients exhibited lower capacities for biofilm production in comparison to the capacities demonstrated by microorganisms isolated from nosocomial patients (29% and 35%, respectively). Area-specific surveillance studies can provide valuable information on UTI pathogens and antimicrobial resistance patterns, which can be useful in guiding empirical treatment.
Description of a Current Outbreak of Mycoplasma pneumoniae in the United States
Authors: Raghuram Anupama , Furmanek Stephen , Chandler Thomas , Rashid Salwa , Mattingly William , Ramirez Julio
Published: January 2025

During the COVID-19 pandemic, a significant decline in Mycoplasma pneumoniae was observed; however, M. pneumoniae re-emerged globally in 2023. Here, we describe a current outbreak of M. pneumoniae infections in the United States (US). More than 287 million patient records from all 50 states in the US were reviewed to identify patients with a M. pneumoniae diagnosis between 1 January 2017 and 30 September 2024. A c-chart was created by calculating the mean and standard error (SE) of cases during the pre-COVID-19 pandemic period, with the upper control limit (UCL) set at 3 SE above the mean. The presence of an outbreak was defined as counts above the UCL. Cumulative excess cases were used to estimate the magnitude of the outbreak, and the fold increase was calculated. A US outbreak of M. pneumoniae began at the end of 2023, resulting in 9708 excess cases corresponding to a 9.0-fold increase over the baseline UCL. The outbreak is ongoing, affects both children and adults, and includes patients with M. pneumoniae community-acquired pneumonia requiring hospitalization. This US outbreak of M. pneumoniae has significant implications for the management of patients with respiratory infections during the current pneumonia season.
Ehrlichia Species in Dromedary Camels (Camelus dromedarius) and Ruminants from Somalia
Authors: Osman Aamir M. , Hassan-Kadle Ahmed A. , André Marcos R. , Collere Flávia C. M. , Córdova Amir Salvador Alabí , Montiani-Ferreira Fabiano , Vieira Thállitha S. W. J. , Ibrahim Abdalla M. , Yusuf Abdulkarim A. , Machado Rosangela Z. , Vieira Rafael F. C.
Published: January 2025

Ehrlichioses, caused by Ehrlichia species, are tick-borne diseases (TBDs) that affect animals and humans worldwide. This study aimed to investigate the molecular occurrence of Ehrlichia spp. in 530 animals (155 Dromedary camels, 199 goats, 131 cattle, and 45 sheep) in the Benadir and Lower Shabelle regions of Somalia. Blood DNA samples were tested for PCR targeting dsb and sodB genes of Ehrlichia spp. and PCS20 and map1 genes of E. ruminantium. The obtained sequences were submitted for phylogenetic analyses. Ehrlichia spp. were detected in 26.4% (140/530) of animals by dsb-PCR, with the highest prevalence in dromedary camels (54.8%), followed by cattle (29.8%), goats (7.0%), and sheep (4.4%). Dromedary camels, cattle, and goats had significantly higher infection odds compared to sheep (p < 0.05). Among dsb-PCR-positive samples, 76.9% (30/39) of cattle tested sodB-positive, while other species were negative. E. ruminantium was detected in 13.7% (18/131) of cattle by pCS20-PCR, but none were positive for the map1 gene. Phylogenetic analysis confirmed E. minasensis in camels, sheep, and goats and E. ruminantium in cattle, marking the first molecular evidence of E. minasensis in dromedary camels, sheep, and goats globally, and E. ruminantium in cattle from Somalia. These findings emphasize the need for further research on its economic and public health impact.
Relatedness of White-Tailed Deer from Culling Efforts Within Chronic Wasting Disease Management Zones in Minnesota
Authors: Fameli Alberto , Jennelle Christopher , Edson Jessie , Hildebrand Erik , Carstensen Michelle , Walter W. David
Published: January 2025

In white-tailed deer (Odocoileus virginianus), closely related females form social groups, avoiding other social groups. Consequently, females infected with chronic wasting disease (CWD) are more likely to infect social group members. Culling has been used to reduce CWD transmission in high-risk areas; however, its effectiveness in removing related individuals has not been assessed. We analyzed 11 microsatellites and a mitochondrial DNA fragment to assess: (1) the genetic structure in white-tailed deer in Minnesota, USA and (2) the effectiveness of localized culling to remove related deer. For (1), we genotyped deer culled in 2019 and 2021 in three CWD management zones, and deer collected in between zones. For (2), we only included culled deer, defining “culled groups” as deer obtained in the same township-range-section and year. We compared mean relatedness among deer from the same culled group (intra-group relatedness) and among deer from different culled groups (inter-group relatedness). We did not find evidence of genetic structure, suggesting that an outbreak in any of the management zones could naturally spread to the others. Culling removed deer that were on average more related than expected by chance (intra-group relatedness > inter-group relatedness), and most highly-related deer were culled in the same bait site.
Social Media, Informed Consent, and the Harm Principle
Authors: Foster Charles
Published: January 2025

This article examines whether social media users can validly consent to their own use of social media. It argues that, whether or not social media use is analogous to public health interventions, there is an obligation to provide users with information about risks and benefits, and absent that provision, there is no valid consent. Many or most users, in any event, do not have the capacity to consent, according to the criteria for capacity articulated in the ‘four abilities’ model: the ability to express a choice, the ability to understand the facts pertinent to the decision in question, the ability of a subject to believe that the information applies to them, and the ability to reason—in the sense of being able to consider and weigh (with reference to the patient’s own concerns, circumstances, and values) the main possible outcomes of the decision to opt for the intervention and the decision to opt not to undergo it. Even if an individual social media user is capacitous according to these criteria, many will fail to be judged capacitous if (as it is argued should be the case), a further criterion, identified by Jennifer Hawkins must be satisfied, namely that the individual can look after their own interests at least as well as most other people can. It follows from this consideration that not only can regulation of social media (in the form of a ban) be justified under Mill’s harm principle, but that non-regulation cannot be justified.
Whom Do I Love When I Love Myself? The Challenge of Narcissism
Authors: Rivera Joseph
Published: January 2025

A central question within contemporary debates about the structure of self-love concerns the place and status of the other. Is self-love identical to, or at least vulnerable to, the accusation of self-absorption and narcissism? Whereas contemporary critiques of self-love argue self-love is in principle impossible, the present essay suggests that self-love can be integrated with the love of the other at an a priori level. This material a priori, distinct from the Kantian formal a priori, entails resources such as commitment to myself, to the other, and to us as relational unit, as well as to the enforcement of boundaries that protects against acts of injury and abuse instigated against that relational unit; I suggest such resources overcome the charge of narcissism levelled at the very idea of self-love. Prior to that, a brief contextual discussion of key moves about philosophical anthropology, focused on the concept of the monad in Leibniz, Husserl and its extreme repudiation in Jean-Luc Marion, is to be addressed. Finally I assess the intimate relationship between self-love and the love of the other inspired in large part by Augustine’s anthropology.
Skepticism and Virtue Epistemology: Wittgenstein and Sosa
Authors: Willliams Michael
Published: January 2025

Ernest Sosa has long been a leading advocate of a virtue-theoretic approach to the traditional problems of epistemology. However, in a recent book his thoughts take a striking new turn. Appealing to our epistemic competencies, he argues, will not suffice to meet the skeptical challenge to our claim to have knowledge of the world around us. We must recognize that our epistemic competencies are exercised against a background of “proper default assumptions”: commitments concerning the world and our place in it that we cannot justify but can rely on without incurring epistemic fault. Sosa finds anticipations of this idea in Wittgenstein’s appeal to propositions “hinge” propositions which, though not known, “stand fast”. However, mere fast-standing beliefs, “unhinged from any broader virtue epistemology”, cannot explain how we come to have knowledge of a world whose character is independent of what we happen to think about it. I argue that the claim that our everyday knowledge of the world rests on a body of assumptions is a serious concession to skepticism, which Wittgenstein shows we need not make. Hinge propositions are not mere “standfast” beliefs: they are known with certainty. Wittgenstein offers a way of thinking about knowledge that Sosa does not consider. He also poses a challenge to commonly held views about how epistemology, to the extent that there is such a subject, should be pursued.
Dual-Wavelength Polarization Multifunction Metalens Based on Spatial Multiplexing
Authors: Shang Xiangshuo , Huang Haiyang , Zhou Yi , Gong Jiaheng , Liu Yang , Li Wei
Published: January 2025

Technological advancements have enabled the active control of electromagnetic waves. Metalenses, known for their precision in wavefront shaping and functional versatility, represent a breakthrough in optical modulation. This study addresses the challenge of achieving dual-wavelength multifunctionality in metalens design. We developed and experimentally validated metalenses with polarization dual-function multiplexing at discrete mid-wave infrared wavelengths, demonstrating high phase fidelity and functional versatility. In addition, the proposed design method was extended to long-wave infrared wavelengths, showcasing its adaptability to different application scenarios. The application of spatial multiplexing significantly enhanced the performance of the metalenses, providing a promising solution for efficient and compact optoelectronic devices.
Direct Hot Solid–Liquid Extraction (DH-SLE): A High-Yield Greener Technique for Lipid Recovery from Coffee Beans
Authors: de Faria Daliane Cláudia , de Queiroz Maria Eliana Lopes Ribeiro , Novaes Fábio Junior Moreira
Published: January 2025

Soxhlet extraction is a method recommended by the Association of Official Analytical Chemists (AOAC) to determine the lipid content in plant samples. Generally, n-hexane (toxicity grade 5) is used as the solvent (≈300 mL; ≈30 g sample) at boiling temperatures (69 °C) for long times (≤16 h) under a chilled water reflux (≈90 L/h), proportionally aggravated by the number of repetitions and samples determined. In this sense, the technique is neither safe nor sustainable for the analyst or the environment. This article presents the development of an alternative and more sustainable procedure for determining the lipid content in raw Arabica coffee beans. A 33 full factorial design was used to perform direct hot solid–liquid extractions in 4 mL vials, varying the ground grains and solvent ratios, temperatures, and times. An optimal condition resulted in an extractive yield statistically equivalent to Soxhlet, without variation in the composition of the oil fatty acids determined by GC-MS after hole oil transesterification. This procedure was presented as a sustainable alternative to Soxhlet extraction because it does not require water for cooling and needs a smaller volume of solvent (2 mL) and sample mass (0.2 g); it also has a smaller generated residue, as well as requiring a shorter time (1.5 h) and less energy expenditure for extraction.
Lomatium Species of the Intermountain Western United States: A Chemotaxonomic Investigation Based on Essential Oil Compositions
Authors: Setzer William N. , Poudel Ambika , Satyal Prabodh , Swor Kathy , Shock Clinton C.
Published: January 2025

Lomatium is a genus of 98 species, widely distributed in western North America. This work presents a chemometric analysis of the essential oils of seven species of Lomatium (L. anomalum, L. dissectum var. dissectum, L. multifidum, L. nudicaule, L. packardiae, L. papilioniferum, and L. triternatum var. triternatum) from the intermountain western United States (Oregon and Idaho). The essential oils were obtained by hydrodistillation and analyzed by gas chromatographic methods. Lomatium packardiae essential oil can be characterized as limonene-rich, L. anomalum is a species rich in sabinene and α-pinene, and L. multifidum essential oils were rich in myrcene, while L. dissectum var. dissectum essential oils were dominated by octyl acetate and decyl acetate, L. papilioniferum essential oils from western Idaho had high p-cymene and 2-methyl-5-(1,2,2-trimethylcyclopentyl)phenol concentrations, while those from Oregon had relatively high β-phellandrene and sedanenolide levels. The essential oils of L. triternatum var. triternatum were too variable to confidently assign a chemical type. The major components in the L. nudicaule essential oils were β-phellandrene (16.0–45.7%), (Z)-ligustilide (5.6–47.1%), (E)-β-ocimene (3.3–9.9%), and δ-3-carene (0.2–12.6%). The enantiomeric distributions of α-pinene, camphene, sabinene, β-pinene, limonene, and linalool were also utilized to discriminate between the Lomatium taxa. There are not enough consistent data to properly characterize L. triternatum var. triternatum or the Oregon L. papilioniferum essential oils. Additional research is needed to confidently describe the chemotype(s) of these species.
Metabolite Profiling and Association Analysis of Leaf Tipburn in Heat-Tolerant Bunching Onion Varieties
Authors: Nakajima Tetsuya , Yamamoto Reina , Matsuse Kanako , Fuji Masato , Fujii Koei , Hirata Sho , Abdelrahman Mostafa , Sato Muneo , Hirai Masami Yokota , Shigyo Masayoshi
Published: January 2025

The bunching onion is an important leafy vegetable, prized for its distinctive flavor and color. It is consumed year-round in Japan, where a stable supply is essential. However, in recent years, the challenges posed by climate change and global warming have resulted in adverse effects on bunching onions, including stunted growth, discoloration, and the development of leaf tipburn, threatening both crop quality and yield. Furthermore, as bunching onion belongs to the Allium genus, which includes globally significant vegetables such as onion and garlic, studying the impact of climate change on bunching onion serves as an ideal model. The insights gained can also be applied to other crops and regions. This study investigates the effects of different summer growth conditions on the metabolite profile of heat-tolerant bunching onions with dark green leaf blade coloration and examines their association with leaf tipburn. Pigment compound quantification, functional component analysis, leaf tipburn rate assessment, and widely targeted metabolome profiling were performed across two commercial F1 varieties, one purebred variety, and six Yamaguchi Prefecture-bred F1 lines under different growing conditions. The results obtained were subjected to comparative analyses based on the varieties and groups classified by high and low leaf tipburn rates. The results revealed that β-carotene accumulation peaked with May sowing and July harvest, while the highest accumulation of other pigment compounds was observed with May sowing and September harvest. Additionally, metabolome analysis related to leaf tipburn rates identified several organosulfur compounds, with gamma-glutamyl-propenyl cysteine sulfoxide emerging as one of the key compounds. Based on the intensity data, the fold change of this metabolite was calculated to be 1.66, indicating an increase in the leaf tipburn group compared to the control group. In the control groups, organosulfur compounds appeared to undergo turnover in preparation for stress response. In contrast, in the leaf tipburn groups, it is hypothesized that organosulfur compounds were converted into precursors of pungency, resulting in inadequate responses to stress. This study aims to elucidate the mechanisms through which organosulfur compounds transition into pungent compounds and to develop varieties with improved resistance to leaf tipburn.
Phosphorus Dynamics in Managed and Natural Soils: SEM-PLS Analysis of Vaccinium, Forest, and Grassland Ecosystems
Authors: Lu Chun , Sugihara Soh , Noma Satoshi , Tanaka Haruo , Tajima Ryosuke , Matsumoto Shingo , Hirose Dai , Zhang Xueyan , Wang Ning , Ban Takuya
Published: January 2025

Phosphorus (P) availability in soils is often constrained by its accumulation in non-labile phosphorus (NLP) forms, limiting its accessibility to plants. This study examines how soil physical properties, chemical characteristics, and climatic conditions influence phosphorus fractionation and the transformation of NLP into plant-available labile phosphorus (LP). Utilizing global structural equation modeling (SEM), we found that silt content enhances organic phosphorus fractions, including NaHCO3-Po and NaOH-Po. In the upper 30 cm of soil, pH decreases the availability of NaHCO3-Po and NaOH-Po while stabilizing NLP, highlighting its essential role in phosphorus cycling under acidic conditions. In deeper soil layers, pH facilitates phosphorus mobilization from NLP pools, with effects varying across fractions. Long-term studies on Japanese Vaccinium soils reveal that pH and electrical conductivity (EC) management significantly promote NLP-to-LP conversion, primarily through NaOH-Po, thereby improving phosphorus use efficiency. These findings underscore the critical importance of prioritizing chemical property management over physical modifications to optimize nutrient cycling, preserve soil fertility, and reduce reliance on external phosphorus inputs in agricultural systems. Our study emphasizes the need for integrated approaches to achieve sustainable phosphorus management in both natural and managed ecosystems.
Microbial Inoculants in Sustainable Agriculture: Advancements, Challenges, and Future Directions
Authors: Díaz-Rodríguez Alondra María , Parra Cota Fannie Isela , Cira Chávez Luis Alberto , García Ortega Luis Fernando , Estrada Alvarado María Isabel , Santoyo Gustavo , de los Santos-Villalobos Sergio
Published: January 2025

The rapid growth of the human population has significantly increased the demand for food, leading to the intensification of agricultural practices that negatively impact the environment. Climate change poses a significant threat to global food production, as it can disrupt crop yields and modify the lifecycle stages of phytopathogens and pests. To address these challenges, the use of microbial inoculants, which are bioproducts containing beneficial microorganisms known as plant growth promotion microorganisms (PGPMs), has emerged as an innovative approach in sustainable agriculture. This review covers the isolation and identification of beneficial strains, the screening and selection process, the optimization of production techniques, and the importance of quality control and field testing. It also discusses the key points for the development and formulation of high-quality microbial inoculants, as well as highlights their advancements, current challenges, and future directions for research and application.
Energy-Efficient Distributed Welding Shop Scheduling Based on Multi-Objective Seagull Algorithm
Authors: Cao Wengang , Peng Runkang , Li Cuiruikai , Li Meimei
Published: January 2025

For the energy-efficient distributed welding shop scheduling problem, focusing on the scheduling of production in a distributed welding shop, a mathematical model is established with the objective of minimizing the makespan and total energy consumption. In order to solve this optimization problem, an improved multi-objective seagull algorithm (IMOSOA) is proposed. The algorithm introduces three main enhancements: designing a weight matrix based on multiple critical paths to update the number of welders allocated to each job, redesigning the discretization operations of the multi-objective seagull algorithm according to the characteristics of distributed welding shop, and incorporating a Pareto front selection strategy. This strategy uses a new crowding distance calculation to resolve cases where non-dominated solutions at the same dominance level have equal crowding distances, thereby improving the next generation of solutions. These improvements not only reduce the maximum completion time and total energy consumption but also enhance search efficiency. Finally, the IMOSOA is compared with other algorithms under different scale examples, and the results show that the energy consumption is at least 11.7% lower than that of the comparison algorithm, which verifies the superiority of the IMOSOA.
A Study on the Residual Oil Distribution in Tight Reservoirs Based on a 3D Pore Structure Model
Authors: Wang Rujun , Zhang Yintao , Sun Chong , Li Jing , Meng Xiaoyu , Yang Chengqiang , Chen Zhaoyang
Published: January 2025

A tight reservoir is characterized by low porosity and permeability as well as a complex pore structure, resulting in low oil recovery efficiency. Understanding the micro-scale distribution of residual oil is of great significance for improving oil production and water flooding recovery rates. In this study, a 3D pore structure model of tight sandstone was established using CT scanning to characterize the residual oil distribution after water flooding. The effects of displacement methods and wettability on residual oil distribution at the micro-scale were then studied and discussed. Moreover, increasing the displacement rate has little effect on the distribution area and dominant seepage channels. Microscopic residual oil is classified into five discontinuous phases according to the oil–water–pore–throat contact relationship. The microscopic residual oil exhibits characteristics of being dispersed overall but locally concentrated. Under water-wet conditions, the injected water tends to strip the oil phase along the pore walls. Under oil-wet conditions, the pore walls have an improved adsorption capacity for the oil phase, resulting in a large amount of porous and membranous residual oil retained in the pores, which leads to a decrease in the overall recovery rate.
Obtaining Nanolignin from Green Coconut Shell and Fiber by the Acetosolv Method with Subsequent Ultrasonication
Authors: Lôbo Larissa Nascimento , de Lima Araújo Rosana Reis , de Andrade Francine Pimentel , Rosas Garcia Almeida Renata Maria , de Farias Silva Carlos Eduardo , de Freitas Jennifer Mclaine Duarte , Duarte de Freitas Johnnatan , da Silva Mariana Barboza , Barcellos França Pedro Henrique
Published: January 2025

This work aimed to extract nanolignin from green coconut husk and fiber using the acetosolv method, with the aim of transforming waste into high-value-added products and promoting sustainability and bioeconomy. The acetosolv pulping was carried out in two stages, varying temperature conditions and the presence or absence of extractives. Lignin was obtained by precipitation and subsequently characterized through chemical and morphological analyses. The analyses of the primary components of the coconut husk and fiber demonstrated lignin, cellulose, and hemicellulose contents of 40%, 15.90%, and 15.86%, respectively. Then, nanolignin was produced through ultrasonication (850 W for 10 and 20 min). The characteristics of the obtained products were analyzed, considering the influence of two temperatures (100 °C and 120 °C) and the need for a pretreatment step (removal of extractives). The temperature variation between 100 °C and 120 °C, as well as the presence of extractives, did not significantly influence the lignin quality or extraction efficiency. The nanolignin produced under this condition was subjected to the DLS technique to determine the hydrodynamic diameter and polydispersity of the nanoparticles obtained, with an average diameter of 533.75 ± 15.12 nm after 20 min of ultrasonication. The purity of the lignin was confirmed by analyses such as the Klason lignin and ash content, which presented values of 78.82 ± 0.81% and 0.55 ± 0.26%, respectively. FTIR analyses revealed typical lignin characteristics, such as the presence of ketone groups, aromatic structures, and methoxylation, while thermograms confirmed the thermal stability of the lignin. Acetosolv pulping proved to be particularly interesting, preserving good quality lignin and allowing for partial recovery of the solvents used, promoting the sustainability and energy efficiency of the process.
The Impact of Recycled Polyethylene Terephthalate as Aggregate Replacement on Mechanical and Ecotoxicological Properties of Mortar
Authors: Legan Maša , Štukovnik Petra , Zupan Klementina , Žgajnar Gotvajn Andreja
Published: January 2025

The purpose of the study was to determine the mechanical and ecotoxicological properties of mortars with differently shaped recycled PET plastics as a partial natural aggregate replacement and assess its environmental impact. Different methods were used for determining mechanical properties, while ecotoxicity tests with two types of plants were performed for the assessment of the ecotoxicological potential of mortars. Results of strength tests revealed that PET in mortars increased 28-day compressive strength by up to 3% and decreased flexural strength by up to 14% compared to conventional mortar. Ultrasonic pulse velocity and dynamic modulus of elasticity were lower in PET mortars, while XRD and SEM-EDS showed fewer hydration products in PET mortars. Duckweed ecotoxicity test results revealed that frond growth inhibition values in PETS and conventional mortar leachate (100 g L−1) were around 50%, while root growth inhibition values did not exceed 40%. Mustard seed germination test results revealed root growth inhibition values in both mortar leachates were lower than 20%. Ecotoxicity tests showed that conventional and PET mortar were non-toxic to duckweed in aquatic environments and non-toxic to mustard seeds in terrestrial environments. Characterization of mortar leachates showed a significant increase in chloride, Ca, Si, and Ba content as potential causes for growth inhibition of both plants. Plastic waste reduction due to the potential use of PET in mortars confirmed that plastic waste could be completely eliminated and the global consumption of primary natural resources for concrete production reduced up to 4%. Such an approach could increase mortar sustainability.
Prohibited Mountains and Forests in Late Imperial China
Authors: Goossaert Vincent
Published: January 2025

This essay explores the various types of spaces, primarily montane forested areas, where human access was restricted, either conditionally or entirely, during late imperial times. The range of restrictions always included felling trees, but often also encompassed other forms of extraction from local ecosystems. Based on the motivations for setting up and regulating such zones, it proposes a typology that includes imperial parks and graves, sacred sites, military exclusion zones, and certain forested commons. Based on some commonalities between these types, it concludes by reflecting on the place of notions of sacrality in local policies that directly impacted forested areas.
A Qualitative Study of Digital Religious Influence: Perspectives from Christian, Hindu, and Muslim Gen Y and Gen Z in Mumbai, India
Authors: Missier Clyde Anieldath
Published: January 2025

This study addresses how religious affective content in digital media influences epistemic authority, social imaginaries, and religious beliefs. It draws on data from 64 in-depth interviews with Generation Y and Generation Z individuals with a higher-education background who identified as Christian, Muslim, or Hindu, conducted in Mumbai, India. While influencers are increasingly playing a significant role in the daily lives of the respondents, the impact of family on religious behavior appears to be more substantial than the epistemic sources on social media. In this context, accrued social capital can help individuals develop resilience or resistance to online disinformation, hate speech, and radicalization. Furthermore, while individuals exhibited animosity toward politicians and journalists, they also expressed nationalist attitudes, e.g., a shared Indian identity and common cultural capital, which may serve as ‘superglue’ for living peacefully in the current climate shaped by religious fundamentalist movements. In general, this field study contributes to the ongoing scholarly growth of the interdisciplinary focus of digital religion studies, and particularly on the impact of the social media domain on fundamentalist beliefs.
(De)Globalization, the Global Imaginary, and Religious Narratives: A Theoretical Framework and the East Asia Litmus Test
Authors: Bai Beilei
Published: January 2025

Faced with the twin challenges of globalization and de-globalization, do religions exercise agency in these trends? In other words, do they give shape to them, or are they rather shaped by them? If the influence is reciprocal, how should the process behind this be described? This article sets itself two tasks. Firstly, it endeavors to develop a theoretical framework by which to conceptualize the question just posed. Secondly, it applies this framework to the case of China and, more cursorily, to the East Asian context in general. I start my analysis by approaching “globalization” as a shared vision of the world, referred to, in this article, as the “global imaginary”. The recent erosion of the latter has led to “deglobalization”, a set of narratives that remain correlated to the globalist storyline they confront. Central to the topic is that fact that the crisis experienced by the global imaginary affects the interplay between its secular and religious dimensions. The secular imaginary had fostered a homogenous narrative that has caused both ontological and epistemological crises. The resurgence of religious discourse within the narratives of deglobalization is to be understood as part and parcel of competing interpretations of the global modernization process, since the latter obeys both secular and religious forces. Focusing in the second part of this article on trends and representations proper to China in its regional context enables us to better assess how the globalization and deglobalization narratives intermingle in religious and secular dimensions in a way that reshapes each of them.
Towards a Holistic Approach to Sustainable Development: Inner Development as a Missing Link for Sustainability Transformation
Authors: Blanc Julia , Meißner Annekatrin
Published: January 2025

The discourse on understanding and implementing sustainable development has so far focused primarily on the external aspects, neglecting the internal dimension of people. The main purpose of our paper is to contribute to addressing this research gap. Therefore, we intend to (1) substantiate existing aspects of the Inner Development Goals (IDGs), (2) complement them, and (3) link the concept of the IDGs to normative discourses in Christian Social Ethics and Social Philosophy. Our results show that the dimensions of Being, Relating, and Collaborating in the IDG Framework can be substantiated by the normative discourse on spirituality and by reference to the social principle of personality in Christian Social Ethics, as well as by the Indian Social Philosophical Perspective of Vimala Thakar which focuses on a value-based approach. This paper suggests that the concept of the IDGs will be strengthened by adding the dimension of Caring—understood as the concern and responsibility for the wholeness in the combining of the inner and outer dimensions. By linking the concept of the Inner Development Goals to the existing normative discourses in Christian Social Ethics and Social Philosophy, our research contributes to making the concept connectable and deepens the discussions on a practical and theoretical level.