bluuebunny/crossref_metadata_2025 huggingface dataset:
Carga de enfermedad de cáncer gástrico desde 2010 hasta 2019 en Tunja, Boyacá, Colombia
Authors: Barreto Noratto Clara Patricia , Limas Solano Luis Manuel , Porras Ramirez Alejandra , Rico Mendoza Alejandro
Published: March 2023

Introducción: el cáncer gástrico (CG) es la primera causa de muerte por neoplasia en Colombia, con 6451 muertes durante el 2020 (1). Esta patología y sus manifestaciones crónicas plantean un desafío en la salud pública; el objetivo fue estimar la carga de enfermedad por CG en Tunja (Boyacá) durante los años 2010 a 2019.
Metodología: se realizó un estudio ecológico exploratorio utilizando como unidad de medida los años de vida ajustados por discapacidad (AVAD). Se emplearon las bases de datos de mortalidad del Departamento Administrativo Nacional de Estadística (DANE), e información de la prevalencia desde los registros del Sistema Integrado de Información de la Protección Social (SISPRO). Las muertes y los casos de CG se agruparon y luego se ajustaron para controlar sesgos.
Resultados: en el período 2010-2019, se perdieron 34,2 AVAD por cada 1000 personas secundario a CG en Tunja, Boyacá, Colombia, de los cuales 30,5 fueron debidos a años perdidos por muerte prematura y 3,72 por años vividos con discapacidad. Se encontró que los AVAD por muerte prematura superan a los AVAD por discapacidad.
Conclusión: la carga de morbilidad por CG en el período 2010 a 2019 para la ciudad de Tunja fue similar a la carga de otros cánceres y fue debido a años de vida perdidos por muerte prematura, motivo por el cual se deben realizar esfuerzos de salud pública para aumentar la detección temprana.
Hígado graso (parte 2): enfoque clínico y tratamiento
Authors: Prieto Ortíz Jhon Edison , Sánchez Luque Carlos Bernardo , Ortega Quiróz Rolando José
Published: March 2023

Los pacientes con hígado graso son casi siempre asintomáticos, las aminotransferasas usualmente están elevadas dos a cinco veces el valor normal y son una causa importante de consulta inicial. Todas las imágenes pueden evidenciar el hígado graso y la biopsia hepática sigue siendo la prueba de oro para su diagnóstico. En cualquier paciente las pruebas no invasivas son una excelente alternativa a la biopsia para determinar el grado de fibrosis hepática y establecer en qué etapa de la fibrogénesis se encuentra. La pérdida de peso y el ejercicio son los pilares fundamentales del tratamiento indicado para todos los pacientes con sobrepeso u obesidad; se recomienda una pérdida de peso entre 5% y 10% del peso corporal y una dieta con restricción calórica de 500-1000 kcal/día, baja en grasas saturadas y rica en productos de la dieta mediterránea como fruta, pescado, verduras, frutos secos, aceite de oliva, entre otros. Hay otros tratamientos como las medidas farmacológicas y los procedimientos endoscópicos y quirúrgicos.
A Review of the development in the multiplex PCR technique for the detection of Bacillus cereus
Authors: Hawani Israa Al , Ibrahim Hayder Hamzah , Khdair Aleem M.
Published: March 2023

Bacillus cereus is a Gram positive rod-shape bacterium, that
causes severe food poisoning. Bacillus form spores that enable it
to resist the environmental stresses, such as drought, heat, pH changes.
Spores can remain dormant for many years, and back to the vegetative
cells when suitable conditions available for bacterial growth. Several
food poisoning outbreaks in cereal products showed that B. cereus
was the main causative agent. Recently, the multiplex polymerase chain
reaction (m-PCR) has provide a rapid and highly sensitive method for the
detection of specific pathogenic microorganisms in the aquatic
environment. To date, most m-PCR assays for pathogen detection have
focused on only one, two or three different types of organisms. The lack
of knowledge in the development of a multiplex PCR assay for the
specific detection of Bacillus cereus inspire us to spot the
light on the development of the method for Bacillus cereus
detection in one rapid multiplex PCR assay and the potential application
of Response Surface Methodology (RSM) for the simultaneous detection of
other multi-pathogen systems.
Effect of bariatric surgery on endometrial cancer regression as part of fertility sparing treatment: A case series and literature review
Authors: Lin Jinlin , Ho Weng Yan , Lim Qi Xuan , Chin Hui Xian Felicia
Published: March 2023

Introduction: Obesity is a major risk factor in the development
of endometrial cancer (EC) in young patients of reproductive age.
Fertility sparing treatment is a viable option for a select group of
patients with early EC, and involves systemic and intra-uterine hormonal
therapy. Weight loss has been associated with improved outcomes in this
group. Bariatric surgery (BS) has been shown to be the most efficient
and durable method of weight loss in obese patients. However, there is a
paucity of data studying the benefit of BS as part of fertility sparing
treatment. Methods: We present a retrospective case series of
five patients who are undergoing fertility sparing treatment for early
EC, who also underwent BS for treatment of obesity and related
comorbidities. We aim to show early regression of EC for all the
patients and also report on the other health benefits of BS.
Results: All five patients in the series achieved regression of
EC within six months of undergoing BS. They also achieved significant
weight loss consistent with previous studies, and three patients who had
comorbidities related to obesity had remission of these conditions. One
of the patients with EC regression also managed to conceive with IVF.
Conclusion: Patients on fertility sparing treatment for early
EC who underwent BS was associated with early regression within 6
months, significant weight loss and resolution of comorbidities. BS
could be a promising component of fertility sparing treatment. Long
term, prospective studies are required to confirm the benefits reported
in this case series.
Free Vibrations of Functionally Graded Porous Hanging and Standing Cantilever Beams
Authors: Sari Ma’en S. , Faroughi Shirko
Published: March 2023

The free oscillations of a functionally graded (FG) porous vertical
cantilever beam in the frame work of Euler-Bernoulli beam theory. The
beam is subjected to the gravity-load and the properties of the FG
material such as the modulus of elasticity and the density are supposed
to change through the thickness of the beam according to power-law
relations. The equation of motion is derived using Newton’s second law.
The Numerical Chebyshev collocation method is utilized to determine the
transverse frequencies of the FG porous hanging and standing cantilever
Euler-Bernoulli beams. A parametric study is conducted to determine the
effects of various factors such as the transverse functionally graded
index, the porosity factor, and the elastic and the mass density ratios
on the natural frequencies and the mode shapes of the FG porous vertical
hanging and standing cantilever thin beams under their self-weight. The
accuracy of the proposed numerical method is evaluated through
comparisons of the frequencies obtained from the present approach with
those available in previous literature.
Flexible Wearable Electronics: Present State and Future Development
Authors: Zhang Qi , Mu Jianjia , Liu Xiao , Gao Xuanwen , Liu Zhaomeng , Luo Wen-Bin
Published: March 2023

Wearable electronics are expected to be light, durable, flexible, and
comfortable. Many fibrous, planar and tridimensional structures have
been designed to realize flexible devices that can sustain geometrical
deformations, such as bending, twisting, folding, and stretching
normally at ambient conditions. As a flexible electrode for batteries or
other devices, it possess favorable mechanical strength and large
specific capacity and preserve efﬁcient ionic and electronic
conductivity with a certain shape, structure and function. To fulfill
flexible energy-storage devices, much effort has been devoted to design
of structures and materials with mechanical characteristics. This review
attempts to critically review the state‐of‐arts with respect to
materials, and structural design of devices as well as applications of
the wearable electronic products. Finally, discussion present regarding
to limitations of current materials, fabrication techniques, devices
concerning manufacturability and performance as well as scientific
understanding that must be improved prior to their wide adoption.
Glutamate spillover provides robust all-or-none behavior of plateau potentials in multicompartment models of striatal projection neurons
Authors: Trpevski Daniel , Khodadadi Zahra , Carannante Ilaria , Kotaleski Jeanette Hellgren
Published: March 2023

Plateau potentials are a critical feature of neuronal excitability, but
their all-or-none behavior is not easily captured in modeling. In this
study, we investigated models of plateau potentials in multi-compartment
neuron models and found that including glutamate spillover provides
robust all-or-none behavior. When glutamate spillover is not included,
the all-or-none behavior is very sensitive to the steepness of the
Mg block. These results suggest a potentially
significant role of glutamate spillover in plateau potential generation,
providing a mechanism for robust all-or-none behavior across a wide
range of slopes of the Mg block curve. We also
illustrate the importance of the all-or-none plateau potential behavior
for nonlinear computation with regard to the nonlinear feature binding
problem.
Relationship between low vitamin D levels with Hashimoto thyroiditis
Authors: Gasic Sanja , Smiljic Sonja , Milanovic Zvezdan , Gasic Milos , Ilic Sladjana , Bogosavljevic Ivan , Dejanovic Mirjana , Nestorovic Vojkan , Matic Tamara
Published: March 2023

Introduction/Objective. Vitamin D not only plays a role in calcium and phosphorus metabolism, but also has antiproliferative, prodifferentiation, anti-inflammatory and immunomodulatory effects. The aim of this study was to investigate the association between vitamin D deficiency in individuals with autoimmune Hashimoto?s thyroiditis. Methods. A total of 156 patients were enrolled and divided into two groups. First group included 108 patients with 25 (OH) D insufficiency, and second included 48 individuals with normal 25 (OH) D levels. All participants underwent a detailed clinical examination, laboratory tests for thyroid function [T3, fT4, TSH, thyroid antibodies (TPO-Ab, and TG-Ab)], as well as ultrasound scanning (thyroid volume and Doppler characteristics). Results. The patients with vitamin D insufficiency (n = 108 (69.2%)) were predominantly female and had a higher body mass index than the patients with normal vitamin D levels. The group with vitamin D insufficiency had statistically significantly higher TSH levels. The prevalence of positive thyroid antibodies was higher in the vitamin D insufficiency group, while thyroid volume, superior thyroid artery, and inferior thyroid arteries resistance index, as well as the prevalence of positive circular dichroism signals, were significantly higher in the vitamin D insufficiency group. Out of the 156 subjects, 44 were diagnosed with thyroiditis (28.2%). The mean serum level of 25 (OH) D was statistically notably lower in patients with thyroiditis (20.23 ? 8.10 ng/mL) than in the group without thyroiditis (25.44 ? 8.38 ng/mL), p < 0.001. Conclusion. There was an association between vitamin D insufficiency and hypothyroidism in subjects with Hashimoto?s thyroiditis.
Copper signal characteristics using collinear LS-DP-LIBS for underwater measurement
Authors: Luo Han , Shen Sijie , Wang Zhenzhen , Yan Junjie , Deguchi Yoshihiro
Published: March 2023

The collinear long-short double-pulse laser-induced breakdown spectroscopy (LS-DP-LIBS) was employed in the detection of underwater copper samples. Discrete emission lines were obtained using LS-DP-LIBS with an appropriate delay between two pulses, while characteristic emission lines were covered by continuous background and noise using LIBS with a single pulse. In the condition of LS-DP-LIBS, signal characteristics of the measured spectra at different experimental parameters including long-pulse width, lens-to-sample distance (LTSD), and long-pulse energy have been investigated to determine the optimal condition. The results indicated that the long-pulse width and the long-pulse energy were closely related to the formation of a cavitation bubble, thus affecting the plasma state and signal characteristics for underwater measurement. The parameter of the LTSD imposed an effect on the spectral signal through changing the ablation mass of the sample and the plasma temperature. The experimental results demonstrated the feasibility of the underwater measurement of metal samples using the collinear LS-DP-LIBS and showed a significant signal improvement through this method. With further development, it is of great potential to apply this new method based on LIBS to ocean exploration.
Estudio florístico y de vegetación del cerro del Peregrino, en los municipios de Acapulco de Juárez y Juan R. Escudero, Guerrero, México
Authors: Gallardo García Ma. Celia , Herrera Castro Natividad D. , López Soto María Martina
Published: March 2023

Guerrero tiene una gran riqueza biológica, sin embargo, aún no cuenta con un listado florístico completo. Los estudios florísticos en el país colocan al estado en el quinto lugar, después de Oaxaca, Chiapas, Veracruz y Jalisco. La zona de estudio se ubica en los municipios de Acapulco de Juárez y Juan R. Escudero, en la Sierra Madre del Sur (SMS), en la parte oriental de una elevación montañosa conocida como cerro del Peregrino. Se realizó un estudio florístico y de vegetación en un área de 1000 ha. Para la elaboración del listado florístico y reconocimiento de los tipos de vegetación, se realizó una recolección de manera exhaustiva en las zonas mejor conservadas. Se identificaron 205 especies, 146 géneros y 61 familias. Se reconocieron siete tipos de vegetación, que corresponden a bosque tropical caducifolio, bosque tropical subcaducifolio, bosque de Quercus, bosque de Quercus-Pinus, bosque de Pinus, bosque de galería y bosque de Byrsonima-Curatella. Astronium graveolens, Cryosophila nana, Calophyllum brasiliense, Microdesmia arborea, Peltolgyne mexicana y Zamia loddigesii se encontraron enlistadas en la NOM-059-Semarnat-2010, en la categoría Amenazada (A) y Agave gypsophila en la categoría Sujeta a protección especial (Pr). La división Magnoliophyta es el grupo dominante y la clase magnoliopsida, la más importante en riqueza florística. La zona de estudio presenta fuerte impacto de deterioro ambiental, por lo que es importante promover programas de manejo forestal para proteger especies en riesgo y dar seguimiento a iniciativas que conserven al cerro del Peregrino como un espacio de gran valor natural, histórico y cultural.
Best Practice Halal Integrity Management in The Logistic Chain Scheme: Analysis of Opportunities and Challenges
Authors: Rizki Darlin , Hamzah Moh. , Fakhiroh Zakiyatul , Hendri Darwin
Published: March 2023

Nowadays, consumers are increasingly aware and concerned about halal status, and activities in the supply chain are truly halal guaranteed for them to buy. This article aims to explore the development of halal logistics, analyze the opportunity and challenge factors in its development stage, and create a best practice scheme to realize halal integrity. This research method uses a Systematic Literature Review (SLR) using secondary data from a number of previous studies discussing halal logistics and halal integrity in the supply chain. From this study, it is known that countries in Southeast Asia have shown a positive response to the existence of a halal logistics scheme as an innovation in the supply chain. Several opportunities known for the development of halal logistics mainly lie in the high demand for halal products, the positive growth of the sharia economy, the use of information technology, and the strengthening of the halal ecosystem. Meanwhile, regarding challenges, there is no special regulation regulating halal logistics, low stakeholder knowledge about halal, a lack of experts and researchers, and the absence of special infrastructure that handles halal products. In the end, the author develops a halal integrity scheme in the supply chain with a logistics management approach. It is hoped that this article can provide a better understanding of halal integrity in the supply chain. Further research can empirically test the relationship between logistics management and halal integrity.
How Zakat Affects Economic Growth In Three Islamic Countries
Authors: Ashfahany Afief El , Hidayah Awalul Dini Nur , Hakim Lukmanul , Mohd Noh Mohd Shahid Bin
Published: March 2023

Zakat as a pillar of development in Islamic economics contributed to the economic development applied in all Caliphate in the Islamic history. By then, this study aims to analyze the effect of zakah on economic growth of three Muslim countries. This study uses a regression estimate of panel data designed to determine the impact of zakat on economic growth with a sample of three Islamic countries in 2003-2020. The results of this study indicate that zakat distribution and population growth have a positive and significant effect on economic growth in three Islamic countries, namely Indonesia, Malaysia and Singapore in 2003-2020. Thus, it can create evidence that zakat can affect economic growth, especially in Islamic countries. This research also supports that zakat should be included in fiscal instrument in today’s world, not only tax. Based on the results of the research above, the student recommend that zakat be included in fiscal policy as is the case with taxes
indicadores de cidades inteligentes e os objetivos de Desenvolvimento Sustentável da Agenda 2030 da ONU
Authors: Benedito Júnior Carlos Alberto , Maluf Eduardo José , Carvalho Marcius Fabius Henriques de , Longo Regina Márcia , Santos Luis Felipe Oliveira
Published: March 2023

O crescimento e desenvolvimento das cidades, desde a mais tenra era, acompanha a degradação do seu meio natural, devasta matas, polui rios e mares, extingui fauna, entre outros. Porém a partir de meados do século passado ocorre o despertar da humanidade sobre a importância da preservação e recuperação do meio ambiente visando proporcionar melhor qualidade de vida e bem-estar para gerações futuras. Em 2015 a Organização das Nações Unidas (ONU) elabora a Agenda 2030 com dezessete Objetivos de Desenvolvimento Sustentável (ODS), sendo um dos pilares a sustentabilidade ambiental como meta de desenvolvimento responsável e inteligente. Nesta mesma esteira de inovação ideológica, pesquisadores desenvolvem o conceito de cidades inteligentes - aquelas que utilizam seus recursos de forma inteligente, e promovem, através da avaliação de diversos indicadores, a classificação do grau de inteligência das cidades. A questão de pesquisa é: estes modelos de representação e avaliação de cidades inteligentes estão alinhados aos dezessete ODS da Agenda 2030 da ONU? Este estudo buscou identificar a conexão e aderência dos indicadores de classificação de cidades inteligentes da metodologia da PoliTIC, na dimensão meio ambiente, com os objetivos da Agenda 2030 relacionados ao tema por meio da comparação par a par destes indicadores como sugerido pelo método AHP. O resultado demonstra que apesar de alguns indicadores estarem mais aderentes aos objetivos estudados que outros, a variação encontrada foi pequena e evidencia que os indicadores desta metodologia estão conectados de modo equivalente com os ODS´s.
ANALISIS KERENTANAN TANAH BERDASARKAN PENGUKURAN MIKROTREMOR DI DESA JATI MULYO, TANJUNG JABUNG TIMUR
Authors: Risa Iwilja Nanda , Maison Maison , Dewi Ira Kusuma
Published: March 2023

Desa Jati Mulyo berada di Kecamatan Dendang Kabupaten Tanjung Jabung Timur yang didominasi oleh gambut sehingga rentan terhadap penurunan muka tanah. Penelitian ini bertujuan untuk mengetahui tingkat kerentanan tanah serta distribusi nilai parameter mikrotremor. Pengukuran dilakukan menggunakan seismograf MAE A6000S sebanyak 36 titik yang tersebar di Desa Jati Mulyo. Analisis data mikrotremor menggunakan metode HVSR (Horizontal to Vertical Spectral Ratio) dengan menggunakan perangkat lunak Geopsy menghasilkan nilai parameter frekuensi alami (f0) dan amplifikasi (A0), selanjutnya perhitungan dilakukan untuk menentukan nilai indeks kerentanan seismik (Kg). Hasil penelitian menunjukkan rentang nilai frekuensi natural area penelitian berkisar antara 0,57 Hz hingga 9,12 Hz. Kemudian nilai faktor amplifikasi berada diantara rentang 1,87 hingga 7,54 dan nilai indeks kerentanan sesimik berada diantara rentang 0,80 hingga 33,44. Berdasarkan Hasil Penelitian, terdapat 3 zona kerentanan seismik pada daerah penelitian, yaitu zona rendah, zona sedang dan zona tinggi. Daerah penelitian di dominasi oleh zona tinggi yang mana hampir seluruhnya tersebar di kawasan penelitian. Hal ini dikarenakan wilayah penelitian merupakan endapan aluvial yang tertutup lahan gambut, maka terdapat bahaya penurunan muka tanah yang tinggi dan dan berpotensi terjadi kerusakan akibat gempabumi.
Uutismediat vastuuttoman yritystoiminnan esiintuojina
Authors: Frig Meri-Maaria
Published: March 2023

Vastuullisuudesta kirjoitetaan yhä enemmän, mutta vastuuttomuuden tutkimus on ollut vähäistä. Tässä artikkelissa tarkastelen, millainen rooli journalismilla on yritystoimintaan liittyvien epäkohtien ja väärinkäytösten selvittämisessä hybridissä mediatilassa. Tutkimukseni pääaineistona on 497 journalistisissa medioissa julkaistua uutisartikkelia, podcastia, radio-ohjelmaa, televisio-ohjelmaa, kolumnia, kommenttia tai pääkirjoitusta. Lisäksi aineistoon sisältyy yritysvastuutapauk- sille keskeisiä sosiaalisen median julkaisuja. Tutkimusaineiston perusteella kriittinen julkisuus liittyy erityisesti yritysten vastuuseen globaalissa taloudessa, työelämän etiikkaan, yritysten viestintään tai ympäristövaikutuksiin. Analysoin artikkelissa, millä tavoin vastuuttomuustapaukset näyttäytyvät journalistisissa medioissa. Tulokset havainnollistavat, miten yritysvastuukohut usein syntyvät erilaisten yhteiskunnallisten toimijoiden yhteistyönä. Voimme toisaalta havaita, miten yritystoiminnan vaikutuksista raportointiin liittyy jännitteitä eri tiedontuottajien välillä. Kansalaisjärjestöt ja vastuullisuusvaikuttajat voivat täydentää uutistoimittajien ja tutkivien journalistien työtä yhteiskunnallisten ongelmien ja epäkohtien esiintuojana.
”Holy shit!!! Jos tuo ei herätä ihmisiä niin sitten ei mikään!”: Salaliittoteoriat ja populistisen kuvittelun kierto hybridissä mediaympäristössä
Authors: Valaskivi Katja , Jääskeläinen Petri , Huhtamäki Jukka , Sumiala Johanna
Published: March 2023

Artikkeli analysoi salaliittoteorioita populistisena kuvitteluna suomenkielisen sosiaalisen median keskusteluissa pandemiavuonna 2020–2021. Artikkelissa populismia tarkastellaan poliittisena genrenä, joka tuottaa ja ylläpitää tietynlaista poliittista kuvittelua ja tunnestruktuuria sekä perustuu eräänlaiseen ideologiseen maailmankuvaan, uskomuksiin sekä käsitykseen todellisuudesta. Tutkimusote on monimenetelmällinen ja yhdistää verkkoetnografista havainnointia ja laskennallisia menetelmiä. Aineisto on koottu Telegramista, Twitteristä sekä kahdelta herätyskristilliseltä verkkosivustolta neljästä uutistapahtumasta maaliskuun 2020 ja maaliskuun 2021 välillä.
Improving the Quality of Workflows is a Means of Systematically Reducing the Risk of Injury to the Coal Mine Personnel
Authors:   Solntsevsky Coal Mine LLC, Cherskikh O.I. , Minakov V.S. ,   Vostochnaya Mining Company LLC, Makarov A.M. ,   LLC «NIIOGR»
Published: March 2023

Relevance of the study is due to a number of factors. Firstly, a typical trend in the activity of coal mines, especially newly opened ones, is an intensive increase in coal production in difficult geological and climatic conditions, while using more and more powerful mining equipment. Secondly, an important circumstance is the use of the shift method of personnel work, which causes its high turnover. These features predetermine an increase in the risk of injury to the coal mines employees. These trends are clearly manifested in the dynamically developing Solntsevo coal mine. In accordance with the general line of the Eastern Mining Company, aimed at further improving production efficiency and occupational safety, a risk management system for negative events is formed at the mine. At the first stage, the employees were introduced to the methodology for identifying hazardous production situations, which they tested in practice in their area of responsibility. The second stage continued mastering this methodology in assessing the risk of identified hazards and developing measures to eliminate them. At the third stage, the employees of the mine began to master the tools for improving the quality of workflows, which is based on an assessment of its main components: personnel, equipment, workflow, and its conditions. Each of these components, in turn, is evaluated against four components. The use of this toolkit allows to identify «narrow» links in the workflow, unsafe operations and actions, the elimination of which reduces the risks of negative events and removes obstacles to efficient work. When testing this toolkit, critical risks were identified, the factors that cause them, measures were developed and taken for implementation to ensure a systematic increase in employee safety when performing the specific operations.
Experimental Study of Working Conditions of Underground Workers in the Heating Microclimate of a Deep Polymetallic Mine
Authors:   Mining Institute UB RAS, Borodavkin D.A. , Zaytsev A.V. ,   Mining Institute UB RAS, Parshakov O.S. ,   Mining Institute UB RAS, Khokhryakov D.S. ,   Mining Institute UB RAS
Published: March 2023

Development of the deep deposits of minerals is inevitably associated with an increase in the temperature of the rock mass and, as a result, an increase in the air temperature in the workings. Working in such conditions reduces the productivity of labour and leads to a deterioration in health of the underground personnel. In the world practice, complex indicators of heat stress are used to accurately assess the microclimate. In the Russian Federation, the index of environmental heat load is most widely used. The article is devoted to the study of microclimatic working conditions of the underground workers of a deep polymetallic mine located in the northern part of the country. As part of the study, all the professions involved in the excavation of a preparatory dead-end development were considered. Among them: a mine foreman, load-haul-dump machine driver, stope miner, a sinker, a driller. At the same time, the microclimatic parameters were continuously monitored at the locations of employees, the heart rate of each of them was constantly recorded, and the type of work performed was also recorded. According to the research results, four out of five professions are classified as a harmful class of working conditions. The most unfavorable conditions were recorded at the sinker. This is due to the long stay of the employee in the dead end during the shift and the severity of the operations performed. The most favorable conditions were recorded for the driver of a load haul dumper, the cabin of which is equipped with an air conditioner.
Usulan Peningkatan Potensi Desa dan Pembuatan Alat Penyaring Air Untuk Masyarakat Desa Botodayaan
Authors: Harsono Harsono
Published: March 2023

Penelitian yang dilakukan di Desa Botodayaan dilakukan secara daring. Sehingga data yang digunakan untuk menyusun penelitian ini didapatkan dengan melakukan studi pustaka sebagai bentuk pengamatan terhadap objek penelitian. Berdasarkan hasil pengamatan tersebut mengenai Desa Botodayaan didapatkan masalah yang sedang dihadapi masyarakat setempat yang berhubungan dengan ketersediaan air bersih, sehingga usulan yang diberikan yaitu berupa pembuatan alat penyaring air. Selain pembuatan alat penyaring air, penulis juga melakukan pemetaan potensi desa yang bertujuan untuk meningkatkan kesejahteraan masyarakat desa.
Pembangunan Agrowisata dan Kuliner Mi Ayam dengan Ektrak Alami di Desa Trirenggo, Kabupaten Bantul, Daerah Istimewa Yogyakarta
Authors: Purnomo Prasetyo Sidi
Published: March 2023

Desa Trirenggo merupakan salah satu desa yang berada di Kapanewon Bantul, Kabupaten Bantul, Daerah Istimewa Yogyakarta. Kelompok 50 periode 80 tahun 2021 merancang sebuah program agrowisata dengan memberdayakan masyarakat sekitar dan juga mengembangkan inovasi mi ayam dengan ekstrak bahan alami. Dengan menerapkan model KKN SOCIETY 5.0, maka rencana kegiatan pengabdian masyarakat kelompok 50 dilakukan dengan metode daring (online) dimana penelitian terkait potensi desa ditelurusi dari internet. Upaya yang kelompok 50 lakukan sebagai hasil dari penelitian dan observasi adalah dengan membuat buku saku rancangan agrowisata yang disajikan dalam bentuk e-book atau buku elektronik beserta video penjelasan, dan juga membuat buku saku yang berjudul “Pembuatan Mi Ayam Dengan Ekstrak Pewarna Alami” beserta video mengenai proses pembuatan mi. Kedua pembahasan yang diteliti oleh kelompok bertujuan untuk menjadikan desa Trirenggo sebagai desa wisata, dengan menggunakan potensi dari desa yang tersedia. Kemudian memberikan gambaran terhadap solusi dari potensi yang telah diambil. Harapan dari program ini adalah dengan gambaran dan ilmu yang telah diberikan dapat menjadi inovasi kepada masyarakat desa Trirenggo untuk perkembangan potensi desa, selain itu juga dapat meningkatkan kepedulian dengan memberikan ilmu kepada masyarakat desa Trirenggo dan menambah wawasan bagi peserta KKN periode 80 Unit J Kelompok 50 dalam memperlajari potensi desa yang tersedia serta menengemukakan solusi sebagai respon dari potensi tersebut.
Perancangan Kawasan Wisata Berbasis Partisipasi Komunitas dan Karakter Lokal di Dusun Trucuk, Desa Triwidadi, Bantul
Authors: Depari Catharina Dwi Astuti , Cininta Mutiara
Published: March 2023

Pariwisata merupakan sektor strategis yang mampu mempercepat laju pertumbuhan ekonomi suatu daerah. Namun, faktor seperti minimnya kesiapan daerah dalam pembangunan dan sumber daya manusia, ditambah dengan dampak global pandemik telah memukul sektor pariwisata hingga berujung pada meningkatnya angka kemiskinan di tanah air termasuk di Kabupaten Bantul. Dalam rangka mengatasi permasalahan tersebut, Pemerintah Kalurahan Triwidadi menjalin kerjasama dengan Universitas Atma Jaya Yogyakarta pada tahun 2022. Berkaitan dengan hal ini, kegiatan pengabdian yang dipaparkan dalam makalah ini bertujuan untuk memberikan pendampingan perencanaan kepariwisataan di salah satu padukuhan, Trucuk, dengan menekankan pada analisis SWOT dan desain fasilitas wisata sebagai generator pertumbuhan ekonomi. Metode pengabdian yang diterapkan pada kegiatan ini didasarkan pada pendekatan partisipasi masyarakat dan karakter lokal. Secara praksis, kegiatan pengabdian senantiasa melibatkan partisipasi warga dalam proses perencanaan demi menghasilkan desain yang merefleksikan karakter lokal. Desain yang diusulkan dalam pengabdian adalah riverwalk, souvenir center dan dermaga sungai, serta panggung budaya di pinggir Kali Progo sebagai atraksi utama wisata dan puncak pergerakan publik melalui koridor lingkungan yang secara spasial perlu ditingkatkan legibilitasnya. Sebagai kesimpulan, kuatnya ikatan sosial dan potensi wisata dusun dapat menjadi modal perencanaan kawasan wisata namun perlu didukung oleh inteventarisasi aset lokal dan data multidisiplin yang komprehensif.
DEVELOPING ASSESSMENT INSTRUMENTS FOR ENGLISH LITERACY IN BLENDED LEARNING FOR JUNIOR HIGH SCHOOL STUDENTS
Authors: Wijaya Eka Anastasia , Ratminingsih Ni Made , Utami IGA Lokita Purnamika
Published: March 2023

This research intended to develop assessment instruments for English literacy in blended learning. The study employed survey, observation, interview, and document study as the methods with a questionnaire, observation checklist, interview guide, and school document as the instruments to collect the data framed within RnD design with the 4D model by Thiagarajan et al. The developed instruments were categorized as ‘very high validity’ and ‘very good’ for their content validity (1.00) and product quality (96% and 98%) by the two judges. It indicates that assessment of learning, assessment for learning, and assessment as learning combined with authentic materials are necessary to improve the learning process as well as the students’ English literacy skills. It also implies that English teachers need to highlight the use of assessment for learning and assessment as learning since those assessments lack attention previously.
The Literacy Approach to Teaching Foreign Languages
Authors: Halbach Ana , Liu Ning
Published: March 2023

Foreign language teachers and researchers who specialize in content and language integrated learning (CLIL) sometimes lack a specific operational pedagogy capable of integrating both language instruction and content education. The book under review introduces a literacy approach that may assist these people in participating in this education. A synopsis of the literacy approach can assist readers of this review in efficiently gaining a comprehensive understanding of the approach. Generally, the literacy approach is divided into two phases, which are respectively dedicated to developing two broad categories of skills: reception and production. The reception phase comprises three steps viz. understanding and enjoying, observing, and analyzing; the production phase comprises two steps viz. guided production and free production. To implement a literacy approach for teaching, the teachers will need to follow a backward design rationale (Wiggins & McTighe, 2005) and considers first the expected students’ output for a social task, then evidence to prove that they have met that expectation, and finally activities and contents to scaffold their learning. A detailed explanation of how the approach works is provided below: 1) During the understanding and enjoying, instructors use pre-tasks to identify students’ potential barriers to understanding a text as well as to engage the students in the text; 2) During the observation, the students are asked to examine a text from both a textual and linguistic standpoint and to discuss how the text draws them into it; 3) During the analysis, instructors assist students in discovering the language qualities that distinguish the text as a skilled communication product; 4) During the guided production, the instructors guide the students in producing a text that is on par with the text they first enjoyed; 5) During the independent production, instructors continue to support students by guiding them to create drafts, edit drafts, and share drafts with peers, as well as guiding them to evaluate each other’s work and training them to be critical readers.
59. Kütüphane Haftası Açılış Konuşması
Authors: KARTAL Ali Fuat
Published: March 2023

59. Kütüphane Haftası açılışında Goethe Enstitüsünde Türk Kütüphaneciler Derneği Genel Başkanı Ali Fuat Kartal tarafından yapılan açılış konuşması.
Menguak Nilai-Nilai Hubb al-Wathan dalam Al-Qashas: 85 (Studi Terjemah dan Tafsir Qur’an Kemenag Digital)
Authors: Rohmati Musfiqotur
Published: March 2023

Indonesia telah berdiri sebagai negara kesatuan berdasarkan lima pilar luar biasa yang menaungi elemen-elemen heterogen di dalamnya. Salah satu pilar yang memperkokoh integrasi di tengah masyarakat multietnik yakni nasionalisme atau sering kita dengar sebagai  hubb al-wathan. Para sarjana muslim berlomba-lomba menyuarakan konsep hubb al-wathan ini sebagai upaya preventif terhadap fenomena hilangnya keutuhan atau persatuan yang menyebabkan perpecahan, termasuk di Indonesia. Namun ketegangan sosial dalam pemaknaan hubb al-wathan sendiri menjadi sebuah fakta aktual yang seolah menolak semangat nasionalisme dengan mempertanyakan validasi konsep hubb al-wathan dalam Al-Qur’an. Kembali, para sarjana muslim pro-nasionalis berlomba-lomba menghadirkan wajah nasionalisme dalam Al-Qur’an dalam berbagai rupa, salah satunya dalam Al-Qashas: 85. Berbagai macam terjemahan berusaha masing-masing dalam menyuarakan konsepsi hubb al-wathan dalam Al-Qur’an termasuk Terjemah dan Tafsir Al-Qur’an Kemenag Digital. Maka tulisan ini berusaha menyajikan penggalian nilai-nilai hubb al-wathan di era kontemporer ini dalam terjemahan dan tafsir qur’an kemenag digital dalam upaya pencegahan disintegrasi nasional atau minimal membendung pembenturan konsep hubb al-wathan di tengah masyarakat multietnik.
Teologi Muhammad Abduh
Authors: Wahid Muhammad Abduh
Published: March 2023

Menarik untuk dikaji corak teologi Muhammad Abduh. Teologi rasionalkah yang mendorong lahirnya dinamisasi atau teologi tradisional yang mendorong kepada kondisi statis. Banyak orang tidak sepakat tentang corak teologinya. Tetapi yang harus dipahami adalah ketidaksepakatan itu merupakan cermin dari bervariatifnya barometer yang dijadikan standar untuk menilainya. Menurut pemikiran Muhammad Abduh tersebut, dapat dipahami bahwa wujud tersusun dari Khaliq dan Makhluk, adanya pencipta dan yang dicipta. Oleh karenanya, semua yang ada dalam wujud ini selain Allah Swt. Adalah makhlukNya. Alam terdiri atas alam abstrak dan alam nyata. Sedangkan alam manusia terbagi ke dalam dua golongan; golongan khawas dan awam. Dalam sistem teologi Abduh, akal mempunyai peranan yang sangat penting. Baginya, untuk memperoleh iman sejati dibutuhkan pemikiran rasional. Yang pasti, bagi Muh. Abduh, wahyu menaruh keyakinan yang amat dalam terhadap keunggulan wahyu dalam membantu akal untuk mengatasi kelemahannya. Yang pasti juga bahwa wahyu tidak hanya berfungsi sebagai informasi, tetapi juga berfungsi sebagai konfirmasi.
EKSISTENSI TAREKAT KHALWATIYAH SAMMAN DI DESA KULO KECAMATAN KULO KABUPATEN SIDRAP
Authors: - Nurdiana -
Published: March 2023

ABSTRACTThis study aims to obtain an objective picture of the existence of the Tarekat Khalwatiyah Samman village Kulo, Kulo district of Sidrap. This is done in an effect to enrich their knowledge in the field research, whose main source is data field, supported by secondary data and literature data. The research is a qualitative descriptive, using the approach include: a philosophical approach, sociological anthropology, sufi and historical approach. The metode used in collecting data are observation, interviews and documentation. Then processed using three strands, namely: resduksi, data presentation and verification of data is analyzed by inductive. The results of this study indicate that the existence of the Tarekat Khalwatiyah Samman in public life Kulo influence in areas such as understanding of religion, economics, politics and governance, social and education in the village of Kulo.Keywords; existence, Tarekat Khalwatiyah Samman.ABSTRAKPenelitian ini bertujuan untuk memperoleh gambaran obyektif mengenai Eksistensi Tarekat Khalwatiyah Samman di Desa Kulo Kecamatan Kulo Kabupaten Sidrap. Ini dilakukan sebagai upaya untuk memperkaya pengetahuan dalam bidang keislaman mengenai aliran tarekat dalam Islam. Penelitian ini adalah penelitian lapangan atau field research, yang sumber utamanya adalah data lapangan, didukung oleh data sekunder dan data pustaka. Jenis penelitian ini adalah deskriptif kualitatif, dengan menggunakan pendekatan diantaranya: pendekatan filosofis, sosiologis, psikologis, teologis, antropologi, sufistik dan pendekatan historis. Metode yang digunakan dalam mengumpulkan data adalah observasi, wawancara dan dokumentasi, lalu diolah dengan menggunakan tiga alur, yaitu: resduksi data, penyajian data dan verifikasi data, selanjutnya dianalisis secara induktif, deduktif dan induktif. Hasil penelitian ini menunjukkan bahwa keberadaan kelompok Tarekat Khalwatiyah Samman dalam kehidupan masyarakat Kulo memberikan pengaruh dalam berbagai bidang seperti pemahaman agama, ekonomi,  politik dan pemerintahan, sosial kemasyarakatan dan pendidikan di Desa Kulo.Kata Kunci: Eksistensi, Tarekat Khalwatiyah Samman
Tangible and Intangible Factors Affecting the Organizational Performance of Remote Health Workers
Authors: Suriyanti Suriyanti , Azlan Shakira Noor
Published: March 2023

The poor performance of local health workers in Indonesia has often been voiced in the regional health facility. This study investigates whether the bureaucratic behaviour, facilities and infrastructure, and organizational culture will increase local health workers' motivation and job performance. This study collects data from 22 local health facilities across Maros Regency, Indonesia, for a quantitative investigation. A response rate of 294 samples is obtained following the normal distribution sampling. The data is then analyzed using the covariance-based Structural Equation Model (CB-SEM) with AMOS software. The results indicate that only facilities, infrastructures, and cultures are crucial for increasing health-worker motivation and job performance. The direct and mediating effects are also reported, with the results discussed with the following implication.
Pharmacokinetics of mavacoxib in New Zealand White rabbits (Oryctolagus cuniculus)
Authors: Wilson Sarah E. , Carpenter James W. , Gardhouse Sara , KuKanich Butch
Published: March 2023

OBJECTIVES

To characterize the pharmacokinetics of a single oral dose (6 mg/kg) of mavacoxib in New Zealand White rabbits (Oryctolagus cuniculus) and to characterize any clinicopathologic effects with this medication and dose.

ANIMALS

Six healthy, 4-month-old New Zealand White rabbits (3 male, 3 female).

PROCEDURES

Before drug administration, clinicopathologic samples were collected for baseline data (CBC, serum biochemical analyses, and urinalysis including urine protein-to-creatinine ratio). All 6 rabbits received a single oral dose (6 mg/kg) of mavacoxib. Clinicopathologic samples were collected at set time intervals to compare with the baseline. Plasma mavacoxib concentrations were determined using liquid chromatography with mass spectrometry, and pharmacokinetic analysis was performed using non-compartmental methods.

RESULTS

After a single oral dose, the maximum plasma concentration (Cmax; mean, range) was 854 (713–1040) ng/mL, the time to Cmax (tmax) was 0.36 (0.17–0.50) days, the area under the curve from 0 to the last measured time point (AUC0-last) was 2000 (1765–2307) days*ng/mL, the terminal half-life (t1/2) was 1.63 (1.30–2.26) days, and the terminal rate constant (λz) was 0.42 (0.31–0.53) days. All results for CBCs, serum biochemical analyses, urinalyses, and urine protein-to-creatinine ratios remained within published normal reference intervals.

CLINICAL RELEVANCE

This study determined that plasma concentrations reached target levels of 400 ng/mL for 48 hours in 3/6 rabbits at 6 mg/kg PO. In the remaining 3/6 rabbits, the plasma concentrations were 343–389 ng/mL at 48 hours, which is below the target concentration. Further research is needed to make a dosing recommendation, including a pharmacodynamic study and investigating pharmacokinetics at different doses and multiple doses.
Cryptocurrency as a method of payment in the tourism sector
Authors: Aiazbekov Azamat
Published: March 2023

The purpose of this study is to look into the capability of cryptocurrencies as a viable alternative to traditional payment methods in the travel and tourism industry. Given the increasing popularity of digital currencies, the tourism industry must consider alternative payment methods. The study's goal is to determine whether cryptocurrencies can be a safe and practical payment option for the travel and tourism industry. The benefits and drawbacks of cryptocurrency adoption in the travel and tourism industry were examined using a case study method. The study focused on customer preferences, security, and regulatory compliance. In-depth research was conducted on a select group of companies that have already implemented cryptocurrency as a payment option, as well as on interviews of business leaders. According to the study's findings, there is a high demand for the adoption of cryptocurrencies in the travel and tourism sector. Customers seeking secure and convenient payment methods may benefit from the use of cryptocurrencies. The study emphasizes the importance of addressing security concerns and regulatory compliance, as these are significant barriers to cryptocurrency adoption in the travel industry. The study provides a road map for cryptocurrency adoption in the travel industry, recommending that the industry focus on developing secure and user-friendly cryptocurrency payment methods, as well as actively collaborate with regulatory bodies to ensure compliance. This case study offers valuable insights to industry participants on how to effectively embrace and use cryptocurrencies in day-to-day business operations. Finally, this study offers a thorough examination of the potential of cryptocurrencies as a new form of payment in the travel and tourism industry. The findings of the study provide a clear understanding of the benefits and drawbacks of using cryptocurrencies, as well as valuable insights for industry participants on how to effectively adopt and use cryptocurrencies in their operations.
Firm performance following foreign acquisitions in Norway: Evidence of profit shifting?**
Authors: Bakke Julia Tropina
Published: March 2023

The paper examines what happened to the profitability of foreign-acquired firms following acquisition in Norway in the period 1994–2005. Propensity score matching combined with a difference-in-difference estimator is used to show that the profitability of the firms acquired goes down significantly following the acquisition. Cost elements, driving the lower profitability of the foreign-acquired firms, are the elements that could reflect transfer price manipulations. Furthermore, the results indicate that despite deteriorating financial performance, there is no significant change in the operating efficiency, liquidity, or solvency of the acquired firms. This may indicate that the observed changes in profitability can be explained by profit shifting activities of the acquired firms.
Synthesis and structure of new modified derivatives based on the quinine molecule and their biological activity
Authors: Mukusheva Gulim , Zhasymbekova Aigerym , Nurmaganbetov Zhangeldy
Published: March 2023

The relevance of the subject matter is conditioned by the constantly growing need to meet human needs in the field of medicine, in particular, the search, study, and further introduction of new types of medicines into practical use. The purpose of this study is to investigate the synthesis of modified quinine alkaloid derivatives, and their structure, to identify the properties and biological activity of antimalarial drugs based on quinine molecules, and to structure the general data of these substances. The leading approach is the analysis of the synthesis of quinine derivatives, their chemical and physical properties, and their ability to exert a medicinal effect. The abstracting method allows structuring alkaloid derivatives and establishing a general relationship between the structural configuration of molecules and their impact on human health in a number of related derivatives. The study identifies the main antimalarial drugs based on quinine molecules, including a comparative analysis of their effectiveness and overall biological activity.