bluuebunny/crossref_metadata_2025 huggingface dataset:
TEMPAT SINGGAH DUKUH ATAS STEPOVER PLACE
Authors: Sanjaya Marseno , Sutisna Sutarki
Published: July 2020

Based on data from PT Kereta Commuter Indonesia (KCI) the number of KRL passengers throughout 2017 reached 315.8 million passengers, up 12.55% from the previous year and will experience an increase every year. With this amount it is known that commuting has also increased. Areas that have easy access to public and strategic transportation are in the center of Jakarta's business district, Dukuh Atas. Hamlet above is also an area with a large commuter population. Every day commuters in Indonesia spend 2-third of their time just waiting and there is repetition. this causes things such as the individual's lack of attention to health, social world and also a high level of stress. Therefore, with the increasing number of passengers and the appropriate area a third place can be created which is a place between the first place and second place that drives humans to build community, equality, and also routines in terms of something positive. For that, we need a place to stop in order to increase productivity and also eliminate the saturation that arises due to repetition that occurs. Then a place was built that had programs such as a bed, a place to chat and also a green room. This building also had room for ticket information that was integrated directly with the Upper Hamlet Station which facilitated access and information accordingly such as departure hours and also when trains arrived.Abstrak Berdasarkan data PT Kereta Commuter Indonesia (KCI) jumlah penumpang KRL sepanjang 2017 mencapai 315,8 juta penumpang naik 12,55% dari sebelumnya dan akan mengalami peningkatan setiap tahunnya. Dengan jumlah ini maka diketahui bahwa komuter juga mengalami peningkatan. Daerah yang memiliki akses yang mudah untuk transportasi umum dan strategis berada di pusat bisnis Jakarta yaitu Dukuh Atas. Dukuh atas juga merupakan daerah dengan penduduk commuter yang besar. Setiap hari kaum komuter di Indonesia menghabiskan 2 per 3  dari waktunya hanya untuk menunggu dan ada pengulangan yang terjadi. hal ini menyebabkan hal seperti ketidakperhatian individu terhadap kesehatan, dunia sosial dan juga tingkat stress yang tinggi .Oleh karena itu, dengan adanya jumlah penumpang yang terus meningkat dan kawasan yang sesuai dapat diciptakannya third place yaitu suatu tempat di antara first place dan second place yang mendorong manusia untuk membangun komunitas,kesetaraan,dan juga rutinitas dalam hal yang bersifat positif.Untuk itu, diperlukan sebuah tempat untuk singgah agar dapat meningkatkan produktivitas dan juga menghilangkan rasa jenuh yang timbul akibat pengulangan yang terjadi. Maka itu dibangunlah sebuah tempat yang memiliki program seperti tempat tidur, tempat untuk bercengkrama dan juga ruang hijau.Bangunan ini juga mempunyai ruang untuk informasi tiket yang berintegrasi langsung dengan Stasiun Dukuh Atas yang mempermudah akses dan informasi yang sesuai seperti jam keberangkatan dan juga waktu kereta datang.
SENAYAN WATERLAKE SPORT ISLAND
Authors: Lim Felicia , Halim Martin
Published: July 2020

Based on the results of the Basic Health Reset in 2018, health problems in Indonesia are divided into two types namely infectious and non-communicable diseases. Infectious diseases have experienced many significant decreases whereas for non-communicable diseases it is still experiencing an increase. Many ways you can do to keep the body healthy from disease. Applying a healthy lifestyle for physical health, spiritual calm is also needed for the mental health of the community, especially for areas that have high density and mobility like in Jakarta. It is undeniable that these factors are often the main triggers of mental health problems in today's society. Waterlake Sport is a type of physical sport related to water, especially lakes. Senayan Waterlake Sport Island is located near Gelora Bung Karno (GBK), the largest sports center in Jakarta and even in Indonesia which provides more than 18 types of sports in it. The design method used is pattern language by examining the physical patterns around the site and creating new patterns by linking the resulting building programs. Besides water sports as the main program, there are also other main programs, namely Healthy Culinary and Floating Market. Both of these programs aim to provide a dining area with a healthy concept as well as education for people who still think that a healthy eating pattern is defined as something boring and unpleasant that being healthy does not have to suffer. AbstrakBerdasarkan hasil Reset Kesehatan Dasar tahun 2018, masalah kesehatan di Indonesia dibagi menjadi dua macam yaitu penyakit menular dan penyakit tidak menular. Penyakit menular sudah mengalami banyak penurunan yang cukup signifikan sedangkan untuk penyakit tidak menular justru masih mengalami kenaikan. Banyak cara yang dapat dilakukan untuk menjaga tubuh tetap sehat terhindar dari penyakit. Menerapkan pola hidup yang Sehat untuk kesehatan jasmani,  ketenangan rohani juga dibutuhkan untuk kesehatan mental para masyarakat khususnya untuk daerah yang memiliki kepadatan serta mobilitas tinggi seperti di Jakarta ini. Waterlake Sport adalah jenis olahraga fisik yang berhubungan dengan air khususnya danau. Island sendiri berarti pulau. Senayan Waterlake Sport Island berlokasi di dekat Gelora Bung Karno (GBK), pusat olahraga terbesar di Jakarta bahkan di Indonesia yang menyediakan lebih dari 18 jenis olahraga di dalamny. Metode perancangan yang digunakan adalah pattern language dengan mengkaji pola fisik di sekitar tapak dan membuat pola baru dengan mengaitkan program bangunan yang dihasilkan. Island yang berarti sebuah pulau merupakan tempat dari area Waterlake Sport itu sendiri. Selain olahraga air sebagai program utama, ada juga program utama lainnya yaitu Kuliner Sehat dan Pasar Apung. Kuliner sehat yang dimaksud adalah  Kedua program ini bertujuan menyediakan suatu area tempat makan dengan konsep sehat sekaligus sebagai edukasi untuk masyarakat yang masih menganggap bahwa pola makan sehat diartikan dengan sesuatu yang membosankan dan tidak enak bahwa menjadi sehat tidak haruslah menderita.
TAMAN BELAJAR MAHASISWA DI GROGOL
Authors: Nathania Devina , Winata Suwardana
Published: July 2020

Technology has been advancing at an incredible pace and has been affecting many things, including the education system. Grogol ,as an education area, is the place where there are three Campus: TRISAKTI, UNTAR, UKRIDA. The students that have lived with advanced technology have a different education system and studying pattern if we compare it with the older generation. The shifting ways of how these students learn require facility to support the transformation. The existing facilities are limited in numbers, type of spaces, and access which requires a flexible learning space that has many varieties and can be accessible at all times. Learning Commons at Grogol provides some facilities that supports the student's learning process. This building form consists of circles and curves as its basic shape to reduce the image of boring and unattractive learning process that is usually done in the square-shaped classrooms in the area. The Learning Commons area, workshop area, library, dance studio, theater, presentation room, etc are designed based on that changing pattern. Studying together is substantial, where students can study by doing presentation/ sharing, discussions, and tutoring. There are also other supporting facilities such as copy machine and printing area, canteen, and stationary store. AbstrakSeiring berjalannya waktu, kita dapat melihat bahwa teknologi mengalami perkembangan yang cukup pesat. Perkembangan teknologi ini membawa banyak perubahan pada berbagai bidang, salah satunya pada bidang pendidikan. Grogol merupakan sebuah kawasan pendidikan, tempat berdirinya tiga perguruan tinggi yaitu TRISAKTI, UNTAR, dan UKRIDA. Para mahasiswa yang mengemban pendidikan di kampus-kampus ini memiliki pola belajar yang berbeda bila dibandingkan dengan generasi sebelumnya karena kemudahan akses informasi. Namun, di dalam kawasan Grogol sendiri masih memiliki keterbatasan fasilitas belajar. Keterbatasan jumlah, jenis, dan aksesibilitas tempat belajar serta perubahan sistem pendidikan menuntut sebuah tempat belajar fleksibel yang dengan mudah dapat diakses kapan saja. Taman Belajar Mahasiswa di Grogol menyediakan fasilitas untuk menunjang kegiatan belajar mahasiswa yang ada pada kawasan Grogol. Bangunan ini didesain dengan bentuk dasar lingkaran untuk mengubah pandangan para mahasiswa terhadap ruang belajar yang membosankan (ruang kelas yang tersedia di dalam kawasan kebanyakan bersifat monoton dengan bentuk kotak dan pola yang serupa). Ruangan - ruangan seperti ruang kerja bersama, ruang workshop, perpustakaan, Studio dansa, theater, ruang presentasi, dll didesain berdasarkan pola belajar mahasiswa yang dipengaruhi oleh perkembangan teknologi. Banyaknya kebutuhan berkumpul untuk belajar menjadi salah satu aspek yang ditekankan dalam proyek ini (belajar bersama dengan cara presentasi, berdiskusi, dan tutoring). Selain itu, disediakan juga beberapa fasilitas penunjang berupa alat fotocopy dan print, kantin, dan juga toko perlengkapan untuk mendukung kegiatan belajar mahasiswa di dalam kawasan.
TAMAN VERTIKAL DI MATRAMAN
Authors: Morgalita Octaviani , Sutanto Agustinus
Published: July 2020

With the rising of number of population and its business, transportation and mobility also rises. Jakarta has the highest number of vehicles and the most polluted metropolitan , as the main problem for Jakarta is the degradation of the environment quality caused by air pollution. Beside poor air quality also affects the physical quality and the population’s psychic which are lung problems, and chronic stress. So, an in-between space is needed as a neutralizer with the purpose of balancing the thinking patters and human health. This neutralizer could be achieved with Matraman Vertical Park. With a total area of about 5.000 m², this place gives humans to “Stop” and “Think” and react positively about the surrounding environment. The site is located between the borders of Jakarta Pusat and Jakarta Timur, specifically, at the intersection of Jl. Salemba Raya and Jl. Pramuka Raya. Matraman Vertical Park is an botanical–garden-integrated public and social space which reacts to the degradation of environment quality in Jakarta. Matraman Vertical Park applies the concept of Third Place which gives human the space to socialize and provide an entertainment that contribute positively to the city environment. The program of this building is open to public and with a purpose for the development of human and the environment. An Interaction space is presented with the concept of morphosis environment to the building’s spaction for visitors. Abstrak Aktivitas transportasi dan mobilitas terus bertambah seiring dengan meningkatnya kesibukan dan pertumbuhan penduduk di kota Jakarta. Kota Jakarta merupakan kota metropolitan dengan jumlah kendaraan dan polusi udara yang tinggi, sehingga permasalahan utama yang timbul adalah penurunan degradasi kualitas lingkungan akibat pencemaran udara. Selain kualitas udara yang buruk juga berdampak pada kualitas fisik dan psikis penduduk yaitu berdampak pada gangguan paru – paru dan chronic stress. Maka dibutuhkannya sebuah ruang antara yang menjadi penetralisir dengan tujuan menyeimbangkan pola pikir dan kesehatan jasmani bagi manusia. Hal tersebut direalisasikan dengan dibuatnya bangunan “Matraman Vertical Park”, dengan luas ± 5.000 m² yang memberikan wadah bagi manusia untuk “Stop” dan “Think”, serta memberikan reaksi positif terhadap lingkungan sekitar. Lokasi bangunan berada di perbatasan antara Jakarta Pusat dan Jakarta Timur yang terletak di persimpangan Jalan Salemba Raya dan Jalan Pramuka Raya. Matraman Vertical Park merupakan ruang publik dan sosial berintegrasi dengan botanical garden yang menjawab dan memperbaiki isu penuruan kualitas lingkungan di kota Jakarta. Matraman Vertical Park menggunakan konsep Third Place yang menyediakan ruang bagi manusia untuk bersosialisasi dan memberikan penghiburan yang berkontribusi positif terhadap lingkungan perkotaan. Di dalam bangunan ini terdapat program yang cenderung ditujukan untuk public dan perkembangan bagi manusia maupun lingkungan, dengan konsep morphosis environment pada tata ruang yang menghadirkan interaction space bagi pengunjung kepada lingkungan sekitar.
RUANG KOMUNITAS DI PESANGGRAHAN
Authors: Japutra Gilbert , Herlambang Suryono
Published: July 2020

The City today is one of many proofs that humans now lead a new and modern life  with multiple technological advancements that supports it, human activities become complex thus altering their lifestyle. Humans have been creating spaces to contain their daily activites. These spaces translates as a hub and from these hubs create communites where humans with the same goals and interests gather. Community Spaces is one of the places where humans connect and take a break from their daily activities and  becomes a Third place for them. Pesanggrahan is one of many urban areas that lacks public facilities that accomodates its inhabitants. Developments of vertical housings nearby makes it even urgent to address the lack of community spaces that provide and accomodates its nearby inhabitants. With the developments of modern public spaces being further and further commercialized, this emphasizes the need to develop a special community space with its purpose to solely provide and serve communities nearby. The methods of study used to respond to this matter are Proxemics and Human Ergonomics Study. Where as these two methods are used to try and fuse personal spaces in order to try and create a community space that is Comfortable, Informal and relaxing to its users. AbstrakKota saat ini merupakan salah satu bukti bahwa manusia telah menjalani kehidupan baru yang modern dengan berbagai perkembangan teknologi yang membuatnya berkembang, aktivitias manusia masa kini semakin kompleks, mengubah gaya hidup mereka. Manusia sejak awal telah menciptakan ruang sebagai wadah aktivitas hidup mereka. Ruang-ruang ini menjadi pusat kegiatan manusia dan dari ruang ini terbentuk komunitas yang berisi manusia-manusia dengan tujuan yang sama. Ruang komunitas menjadi salah satu tempat bagi manusia untuk berkoneksi dengan manusia lain, menghilangkan kejenuhan dari kesibukan sehari-hari, ruang ini menjadi tempat ketiga bagi mereka. Pesanggrahan merupakan salah satu area yang ramai dengan hunian dan kurang adanya fasilitas pewadah interaksi komunitas, apalagi dengan cukup banyak hunian vertikal yang ada disekitarnya keberadaan sebuah ruang public yang netral sangat dibutuhkan.  Proyek ini bertujuan untuk menjawab kebutuhan masyarakat pesanggrahan khususnya penghuni Puri Park View dan sekitarnya akan ruang komunitas yang netral dan nyaman. Dengan banyaknya ruang publik yang semakin di komersialkan keberadaan ruang komunitas semakin dicari-cari. Metode perancangan yang digunakan berupa pendekatan Proxemics yang didasari oleh buku Edward Hall The Silent Language dan studi Ergonomi manusia. Keduanya digunakan dengan tujuan untuk meleburkan ruang personal agar memungkinkan terbentuknya sebuah ruang komunitas yang nyaman, informal dengan kesan santai bagi penggunanya.
SARANA KREATIFITAS, REKREASI, DAN KOMUNITAS DI KAWASAN RS FATMAWATI, JAKARTA SELATAN
Authors: Widjaja Ivana , Anggraini Diah
Published: July 2020

Very tight working hours and a lot of work assignments can cause high level of stress. Therefore, every individual need a place that can help them escape from stress and fatigue. In order to meet these needs, an entertaining public space is very much needed in order to meet human needs. This study aims to produce a 3rd place design concept that can overshadow a variety of activities as mentioned above. In compiling this design concept, it will refer to the method of observation, while understanding the location of both the physical and socio-cultural conditions of the community, descriptive qualitative research will be used. This study resulted in the design concept and design of a 3rd place in the Fatmawati area of South Jakarta. AbstrakJam kerja yang sangat padat dan tugas-tugas pekerjaan yang banyak dapat menyebabkan adanya beban pikiran dan stress. Oleh karena itu, setiap individu pasti membutuhkan tempat yang dapat membantunya melepaskan diri dari stres dan lelah. Dalam rangka memenuhi kebutuhan tersebut, maka sebuah ruang publik yang bersifat menghibur sangat dibutuhkan keberadaanya dalam rangka memenuhi kebutuhan manusia. Kajian ini bertujuan menghasilkan konsep perancangan suatu 3rd place yang dapat menaungi berbagai aktifitas sebagaimana tersebut di atas. Dalam menyusun konsep perancangan ini, akan mengaju pada metode observasi, sementara pemahaman terhadap lokasi baik fisik maupun kondisi sosial budaya masyarakat, akan digunakan riset kualitatif deskriptif. Kajian ini menghasilkan konsep perancangan dan perancangan suatu 3rd place di kawasan Fatmawati Jakarta Selatan.
Direct Displacement Control of Deformed Double Layer Dome
Authors: Mohammed Saeed Najmadeen , Jabar Abdulkarim Shna , Ali Haji Hawkar
Published: July 2020

Space structures such as double layer dome is light and active structural system that used for various structural application, for instance structural covers large areas such as exhibition halls, stadium and concert halls. They are aesthetically pleasing in appearance as well as the architectural requirement, in which tolerances of structural shape under changing service conditions are very significant, which high appearance accuracy is requested in some applications. Due to many reasons such as loading, these type of structures may suffer from a noticeable deflection, which leads to a significant potential undesired appearance of the shape. In this situation, the displacements may need to be reduced or eliminated. In this study, by applying the shape adjustment technique that its scheme is depend on the linear force method, shape restoration is performed to the double layer dome model in three different cases corresponding to the directions of loadings were considered. The improvement of controlling nodal displacement can be achieved through using a rather simple and direct method, due to calculating necessary length of actuators by applying a single formulation. It is found that if the number of provided actuators are satisfactory, controlling of all the displaced joints could be performed by a very small percentage of discrepancy, even if the controlled joints connection is not direct with the adjustable members. The technique of shape adjustment is very efficient for double layer dome model, and it can roughly eliminate the displacement of definite joints (Exterior joints only) by simply changing the length of certain bars by eo amount
Review of the Methods for Strengthening and Retrofitting Cultural Heritage Structures
Authors: Wafaei Baneh Bira , Wafaei Baneh Koosha Wafaei Baneh
Published: July 2020

Referring to the fact that the history of each country is the identity of its people and the preservation of originality and culture is also considered as a social value, the maintenance of valuable historical monuments, which indicates the path to the growth of human civilization, is of particular importance. Each country is trying to prevent the destruction of its historic buildings and cultural heritage by applying various methods of reparation and retrofitting. Iran, as a country with an ancient civilization, is a heritage of many valuable historical monuments. Traditional construction materials included masonry materials such as clay and mud, stone, wood and brick, and due to the weakness in physical structure and their low shear capacity and tensile strength, these materials do not have strength for example against strong forces from earthquakes and are suffered heavy damages. Unfortunately, in our country, fundamental work has not been performed on historical sites and complexes so far, and practically, the measures have been taken without any improvement in the structural performance of the buildings. Using special technical and specialized methods, the seismic behavior of such buildings could be enhanced against the seismic forces caused by the earthquake, and minimize the damage on the historical buildings to the least possible extent by strengthening historical monuments. In this paper, by separating the components, we examine a number of strengthening methods belonging to each of them.
Laying foundation of a successful social enterprise: case study of Junior Chamber International (JCI) Lipa’s Project GANAP
Authors: Resurreccion Analiza D.
Published: July 2020

This case study underscores the significance of the different livelihood assets including human capital, financial capital, natural capital, physical capital, and social capital in the initiation phase of Junior Chamber International (JCI) Lipa’s Gawaing Nagpapaunlad ng Pangkabuhayan or Project GANAP. These assets were tagged necessary in the pursuit of positive livelihood outcome that is to uplift the lives of the families in Sitio Hillview in Lipa City, Batangas. In- depth interviews with JCI Lipa key persons and focus group discussion with women participants were conducted by the researcher to determine how the aforementioned livelihood assets were utilized by JCI Lipa. Gathered data revealed that utilization of the livelihood assets is subject to some vulnerabilities, thus sustainability efforts are paramount.. The researcher recommends that since livelihood assets potentially affect the use of other livelihood assets and effective utilization, thus, a study on the mutual impact of these assets not just with Project GANAP but with other governmental and non- governmental social enterprise initiatives be pursued in the future research.
Zanikanie granic między klasami społecznymi. O potrzebie poszukiwania alternatywnych segmentacji społecznych
Authors: Urbaniak Paweł
Published: July 2020

A description of borderland as a space can be inspiring for an analytical presentation of other social phenomena in which coexisting borderline categories occur. An example is social stratification within which different groups of individuals referred to as layers, castes or classes can be distinguished. Their character is arbitrary, resulting from a concern for the conventional, often not very distinctive interests of some social groups. Since the 19th century, the most widespread stratification system in Western societies has been the class system. However, its analytical value has been fading due to the blurring of boundaries between particular classes. The social classes, on the one hand, are subject to strong internal differentiation and are losing their previous cohesion, and on the other hand, they are becoming similar in many respects. Therefore there is a need to create an alternative and more analytically useful way of categorizing societies in contemporary social sciences. Segmentation based on the category of lifestyle seems valuable, because lifestyle is what, in a particularly important way, differentiates in the social dimension individuals forming contemporary Western societies. At the same time, this category is so capacious and distinctive that it can be analytically useful for representatives of various social sciences. The aim of the paper is, first of all, to present the structural foundation of class systems, secondly, to identify the reasons for the loss of their analytical value, and thirdly, to discuss the scientifically useful segmentation of society relating to different lifestyles.
Researching cross-border cooperation under the shadow of COVID 19 pandemic: scientific report from e-conferences and blog-reflections produced between 14 March and 21 June 2020
Authors: Böhm Hynek
Published: July 2020

The aim of this paper is to try to summarize, how, the scholars researching border studies and cross-border cooperation practitioners reacted to the COVID-19 pandemic during the period from 16 of March to 21 of June 2020. As it was not possible to follow all the texts (often published without peer-review in thematic blogs) and events, the overview is not exhausting. Another goal of this text is to synthesize the main messages of those texts and events and to identify possible future trends in border studies. We will most likely experience the discourse change which will lead us towards studying impacts of re-bordering rather than de-bordering. We can also expect the lower engagement of the local and regional actors in cross-border cooperation, which will be in some border contexts considered as an unnecessary luxury.
“Hino ao canto do galo”, de Prudêncio
Authors: Carvalho Abrantes Miguel
Published: July 2020

Esta é uma tradução para Português do Hymnus ad Galli cantum.
Gênero e caracterização na Medeia de Eurípides
Authors: Crepaldi Clara Lacerda
Published: July 2020

Este trabalho examina a caracterização da personagem Medeia na tragédia homônima de Eurípides. Em primeiro lugar, observo como os seus discursos se conformam aos padrões de fala geralmente identificados como femininos na tragédia e como ela usa falsas fórmulas de submissão para enganar seus adversários. Em segundo lugar, investigo em que medida sua caracterização linguística também contém traços de um heroísmo mais tipicamente masculino, deixando entrever medos e angústias subjacentes aos estereótipos femininos da tragédia.
De Ovídio a Sor Juana Inés de la Cruz: o tímido monarca Actéon em Primero Sueño
Authors: Fernández Zambudio Josefa
Published: July 2020

Neste artigo estudamos a menção ao cervo no poema Primero sueño, no qual acompanhamos a alma em seu voo em busca de conhecimento. Este é um exemplo significativo da recepção da cultura clássica no Barroco mexicano, que, devido às numerosas referências ao mundo antigo, devemos conhecer para que se compreenda o poema. Sor Juana Inés de la Cruz dedica alguns versos ao cervo, identificando-o com o mítico caçador Actéon: antes monarca, ora medroso animal que dorme inquieto. Analisamos as fontes do mito de Actéon e do símbolo do cervo, e aprofundamo-nos no principal intertexto da recepção da mitografia em Primero sueño, Metamorfoses de Ovídio. Delimitamos quais são as características do cervo e do mito desenvolvidas pela autora em relação ao contexto no poema. Além disso, examinamos a denominação “monarca” para Actéon
A Predictive Model of the Temperature-Dependent Inactivation of Coronaviruses
Authors: Yap Te Faye , Liu Zhen , Shveda Rachel A. , Preston Daniel
Published: July 2020

The COVID-19 pandemic has stressed healthcare systems and supply lines, forcing medical doctors to risk infection by decontaminating and reusing single-use medical personal protective equipment. The uncertain future of the pandemic is compounded by limited data on the ability of the responsible virus, SARS-CoV-2, to survive across various climates, preventing epidemiologists from accurately modeling its spread. However, a detailed thermodynamic analysis of experimental data on the inactivation of SARS-CoV-2 and related coronaviruses can enable a fundamental understanding of their thermal degradation that will help model the COVID-19 pandemic and mitigate future outbreaks. This paper introduces a thermodynamic model that synthesizes existing data into an analytical framework built on first principles, including the rate law and the Arrhenius equation, to accurately predict the temperature-dependent inactivation of coronaviruses. The model provides much-needed thermal decontamination guidelines for personal protective equipment, including masks. For example, at 70 °C, a 3-log (99.9%) reduction in virus concentration can be achieved in ≈ 3 minutes and can be performed in most home ovens without reducing the efficacy of typical N95 masks. The model will also allow for epidemiologists to incorporate the lifetime of SARS-CoV-2 as a continuous function of environmental temperature into models forecasting the spread of coronaviruses across different climates and seasons.
Dynamics and Spectroscopy of Molecular Ensembles in a Lossy Microcavity
Authors: Ulusoy Inga , Vendrell Oriol
Published: July 2020

The radiative and nonradiative relaxation dynamics of an ensemble of molecules in a microcavity are investigated with emphasis on the impact of the cavity lifetime on reactive and spectroscopic properties. We show that the dynamics of the ensemble and of single molecules are influenced by the presence of a cavity resonance as long as the polariton splitting can be resolved spectroscopically, which critically depends on the lifetime of the system. Our simulations illustrate how the branching between nonradiative intersystem crossing and radiative decay through the cavity can be tuned by selecting specific cavity photon energies resonant at specific molecular geometries. In the case of cavity-photon energies that are not resonant at the Franck-Condon geometry of the molecules, it is demonstrated numerically and analytically that collective effects are limited to a handful of molecules in the ensemble.
Diagnosis of Fatty Liver Disease by a Bright, Multiphoton-Active and Lipid-Droplet-Specific AIEgen with Nonaromatic Rotors
Authors: Park Hojeong , Li Shijie , Niu Guangle , Zhang Haoke , Song Zhuoyue , Lu Qing , Zhang Jun , Ma, Chao , Tsz Kin Kwok Ryan , Lam Jacky W. Y. , Wong Kam Sing , Yu Xiaoqiang , Xiong Qingping , Tang Ben Zhong
Published: July 2020

Fatty liver disease (FLD) has become an increasing global health risk. However, an accurate diagnosis of FLD at an early stage remains a great challenge due to lack of suitable imaging tools. To this end, we developed the first fluorescent two-photon aggregationinduced emission (AIE) luminogen ABCXF for high-contrast imaging of FLD tissue. ABCXF has a large Stokes shift, good two-photon absorption cross-section, bright red emission, high fluorescence quantum yield in solid state, and excellent photostability. It shows abnormal intramolecular charge transfer effect instead of twisted intramolecular charge transfer effect in polar solvents. Photophysical and crystal data demonstrated that it exhibits nonaromatic rotors - trifluoromethyto contribute to its AIE effect. Biocompatible lipid droplet-targeting ABCXF can selectively light up lesions in the FLD tissue with a high signal-to-noise ratio. It shows superior imaging performances compared to Oil Red O. Thus, ABCXF can be a powerful tool for the diagnosis and evaluation of FLD from a liver biopsy.
In Silico Screening of Phytochemicals of Ocimum Sanctum Against Main Protease of SARS-CoV-2
Authors: Mohapatra Pranab Kishor , Chopdar Kumar Sambhav , Dash Ganesh Chandra , Raval Mukesh Kumar
Published: July 2020

COVID19 has compelled the scientific community to search for an effective drug that can cure; a vaccine or an immunity booster that can prevent the disease. As of now, it is tough to discover a new drug and vaccine discovery is even tougher. Drug repurposing is a shortcut to drug discovery for COVID19. Even this has been proved unsatisfactory. Symptomatic treatment and immunity boosters are only alternatives left. Holy Tulsi (Ocimum sanctum) has been known as an ancient remedy for cure of common cold and respiratory ailment in India vis-a-vis also has been prescribed as one of the recommended ingredients in the immunity booster preparations. The ethanolic extract of aerial parts of Tulsi is reported to contain flavonoids and polyphenolic acids, which are also reported earlier to have anti-viral properties experimentally. Therefore, we undertake the in silico analysis of the phytochemicals as inhibitors of main protease of SARS-CoV-2 virus. The result suggests that the flavonoids and polyphenolic compounds of Tulsi, especially luteolin-7-O-glucuronide and chlorogenic acid may covalently bind to the active residue Cys145 of main protease and irreversibly inhibit the viral enzyme. Further experimental validations are required to establish the theoretical findings.
Fast and Automatic Estimation of Transition State Structures Using Tight Binding Quantum Chemical Calculations
Authors: Rasmussen Maria Harris , Jensen Jan H.
Published: July 2020

We present a method for the automatic determination of transition states (TSs) that is based on Grimme’s RMSD-PP semiempirical tight binding reaction path method (J. Chem. Theory Comput. 2019, 15, 2847-2862), where the maximum energy structure along the path serves as an initial guess for DFT TS searches. The method is tested on 100 elementary reactions and located a total of 89 TSs correctly. Of the 11 remaining reactions, nine are shown not to be elementary reaction after all and for one of the two true failures the problem is shown to be the semiempirical tight binding model itself. Furthermore, we show that the RMSD-PP barrier is a good approximation for the corresponding DFT barrier for reactions with DFT barrier heights up to about 30 kcal/mol. Thus, RMSD-PP barrier heights, which can be estimated at the cost of a single energy minimisation, can be used to quickly identify reactions with low barriers, although it will also produce some false positives.
Potential of Terminalia Arjuna as a Promising PhytoremedyAgainst COVID-19: DPPH Scavenging, Catalase Inhibition and Molecular Docking Studies
Authors: Arumugam Senthilkumar , Dash Swati Sucharita , Mitra Kartik , Doble Mukesh , N.Gummadi Sathyanarayana
Published: July 2020

Stem and bark of the tree Terminalia arjuna Wight &Arn. (Combretaceae) has been documented to exhibit therapeutic properties like cardiotonic, anticancer, antiviral, antibacterial, antifungal, hypocholsteremic, hypolipidemic and anti-coagulant. In previous studies, ethanolic extract of T.arjunabark effectively inhibited catalase activity along with demonstration of DPPH radical scavenging activity. Further,four known oleananetriterpenoids type compounds viz., oleanolic acid, arjunolic acid, arjunolitin, arjunetin were isolated from ethaolic bark extract and the structures of which were elucidated using 1 H, 13C NMR, HR-ESIMS, IR and compared with literature data. Of the various compounds, Arjunetin showed significant inhibition of catalase activity as compared to the other compounds and most probably conferring antibacterial and antiviral property of the extract. In the present study, considering the currently on going viral pandemic of SARS-CoV-2 and the need for an effective antiviral agent, T.arjuna with its cardioprotective ability and inhibitory action against catalase presents to be a promising candidate against the virus. Molecular docking studies showed that arjunetin binds to protease of SARS-CoV-2 (3CL, PL andRdRP) and had higher binder energy values (3CL, -8.4 kcal/mol; PL, -7.6 kcal/mol and RdRP, -8.1 kcal/mol as compared with FDA approved protease inhibitor drugs lopinavir (3CL, -7.2 kcal/mole and PL -7.7 kcal/mole) and Remdesivir (RdRP -7.6 kcal/ mole). We conclude that there is profound evidence of arjunetin as a potential protease inhibitor of SARS-CoV-2 which is comparable to FDA approved antivirals Lopinavir and Remdesivir and can serve as a candidate for drug development against SARS-CoV-2.
CHARMM-DYES: Parameterization of Fluorescent Dyes for Use with the CHARMM Forcefield
Authors: Shaw Robert , Johnston-Wood Tristan , Ambrose Benjamin , Craggs Timothy , Hill Grant
Published: July 2020

We present CHARMM-compatible forcefield parameters for a series of fluorescent dyes from the Alexa, Atto and Cy families, commonly used in F¨orster resonance energy transfer (FRET) experiments. These dyes are routinely used in experiments to resolve the dynamics of proteins and nucleic acids at the nanoscale. However, little is known about the accuracy of the theoretical approximations used in determining the dynamics from the spectroscopic data. Molecular dynamics simulations can provide valuable insights into these dynamics at an atomistic level, but this requires accurate parameters for the dyes. The complex structure of the dyes, and the importance of this in determining their spectroscopic properties, means that parameters generated by analogy to existing parameters do not give meaningful results. Through validation relative to quantum chemical calculation and experiment, the new parameters are shown to significantly outperform those that can be generated automatically, giving better agreement in both the charge distributions and structural properties. These improvements, in particular with regards to orientation of the dipole moments on the dyes, are vital for accurate simulation of FRET processes.
Ligand-Mediated Spin State Changes in a Cobalt-Dipyrrin-Bisphenol Complex
Authors: van Leest Nicolaas P. , Stroek Wowa , Siegler Maxime A. , van der Vlugt Jarl Ivar , de Bruin Bas
Published: July 2020

ABSTRACT: The influence of a redox-active ligand on spin changing events induced by coordination of exogenous donors is investigated within the cobalt complex [CoII(DPP•2‒)], bearing a redox-active DPP2‒ ligand (DPP = dipyrrin-bis-(o,p-di-tert-butylphenolato) with a pentafluorophenyl moiety on the meso-position. This square planar complex was subjected to coordination of THF, pyridine, tBuNH2 and AdNH2 (Ad = 1‑adamantyl), and the resulting complexes were analyzed with a variety of experimental (XRD, NMR, UV-Vis, HRMS, SQUID, Evans’ method) and computational (DFT, NEVPT2-CASSCF) techniques to elucidate the respective structures, spin states and orbital compositions of the corresponding octahedral bis-donor adducts, relative to [CoII(DPP•2‒)]. This starting species is best described as an open-shell singlet complex containing a DPP•2‒ ligand radical that is antiferromagnetically coupled to a low-spin (S = ½) cobalt(II) center. The redox-active DPPn‒ ligand plays a crucial role in stabilizing this complex, and in its facile conversion to the triplet THF-adduct [CoII(DPP•2‒)(THF)2] and closed-shell singlet pyridine and amine adducts [CoIII(DPP3‒)(L)2] (L = py, tBuNH2 or AdNH2). Coordination of the weak donor THF to [CoII(DPP•2-)] changes the orbital overlap between the DPP•2‒ ligand radical π-orbitals and the cobalt(II) metalloradical d-orbitals, which results in a spin-flip to the triplet ground state without changing the oxidation states of the metal or DPP•2‒ ligand. In contrast, coordination of the stronger donors pyridine, tBuNH2 or AdNH2 induces metal-to-ligand single-electron transfer, resulting in formation of low-spin (S = 0) cobalt(III)-complexes [CoIII(DPP3‒)(L)2] containing a fully reduced DPP3‒ ligand, thus explaining their closed-shell singlet electronic ground states.
Kognitív tudományok az ítélkezési tevékenység szolgálatában
Authors: Gábri Angéla
Published: July 2020

Napjainkra meghaladottá vált az a nézet, hogy a bírák csak jogszolgáltatást végeznének. Alapvető elvárás, hogy a „jó bíró” számtalan olyan készséggel, képességgel rendelkezzen, amelyek megszerzéséhez és fejlesztéséhez nem a jogtudomány nyújt majd segítséget. Ha elfogadjuk, hogy „a bírák is emberek,” el kell fogadnunk azt is, hogy elméjükre és döntéshozatali folyamataikra is az általánosan elfogadott tudományos törvényszerűségek vonatkoznak. A kognitív tudományok robbanásszerűen felkapott eredményei kevésbé ismertek hazánkban, pedig ezek segítségével az ítélkezés szubjektív elemei tovább csökkenthetők, a tudatosság pedig pontosabb döntések meghozatalához vezethet.
Elosztott mesterséges intelligencia fejlesztés blokklánc alapon az adatvédelem érvényesülése érdekében
Authors: Eszteri Dániel
Published: July 2020

A tanulmány célja bemutatni néhány olyan alapvető adatvédelmi jogi elvet, amelyek alkalmazásával megfeleltethető lehet a blokkláncban kezelt személyes adatok és azokkal végzett automatikus döntéshozatal technológiája az Európai Unió általános adatvédelmi rendelete (GDPR) előírásainak. Az ilyen típusú rendszerek fejlesztése során a „beépített adatvédelem” elvére helyezi az elemzés a hangsúlyt. Feltevésem, hogy mivel a blokklánc elosztott alapú adatkezelést lehetővé tévő hálózat, ezért az abban résztvevő minden egyes csomópont adatkezelése vagy adatfeldolgozása során érvényesülnie kell bizonyos előre meghatározott, már a fejlesztés során kollektívan beépített és jelen lévő absztrakt adatkezelési mintázatoknak. A jobb megértés érdekében az emberi tudatot és annak tudatos és tudattalan tartalmakkal való „feltöltését” hoztam analógiaként. Fő célom ezáltal rávilágítani arra, hogy a blokklánc és a gépi tanuláson alapuló mesterséges intelligencia két olyan technológia, amelyek összekapcsolása alkalmas komoly automatikus döntéshozó rendszerek (ún. „elosztott MI”) fejlesztésére. Ezen elosztott MI-t használó rendszerek adatvédelmi jogi megfelelése a nagyon komoly kockázatok miatt olyan kulcskérdés, amivel – a technológia fejlődési irányait szem előtt tartva – érdemes komolyabban is foglalkozni.
Developing Physics Comprehensive Contextual Teaching Material Based on KKNI in Work and Energy for High School Students
Authors: Arifiyanti Fitria , Suparno Suparno
Published: July 2020

This research aimed to (1)produce Physics Comprehensive ContextualTeaching Material (PhyCCTM)based on KKNI which feasible in work and energy,(2)know the improvement of student’s higher-order thinking skills (HOTS)by using PhyCCTM based on KKNI in work and energy, (3)know the improvement of student’s scientific attitude by using PhyCCTM based on KKNI in work and energy, (4) know the effectivity of PhyCCTM based on KKNI in work and energy to improve student’s HOTS and scientific attitude. The procedure of development in this research referred to the steps procedural model adapted from Borg & Gall model, which has six steps. Data collection techniques used interviews, written tests, questionnaires, and observations. Data analysis technique for the improvement in students HOTS and scientific attitude used the gain score to see its effectiveness and MANOVA to see the significance of the difference between the control class and the experimental class. The results of this research were as follows. (1) PhyCCTM based on KKNI can be reasonably used with the category of "Very Good." (2) PhyCCTM based on KKNI can improve student’s higher-order thinking skills. (3) PhyCCTM based on KKNI can improve a student’s scientific attitude. (4) PhyCCTM based on KKNI can improve student’s higher-order thinking skills and scientific attitude.
Penerapan Model Pembelajaran Problem Solving Berbasis Demonstrasi terhadap Peningkatan Hasil Belajar Siswa pada Materi Suhu dan Pengukurannya
Authors: Andella I’ip , Kusumawati I , Murdani Eka
Published: July 2020

Penelitian ini bertujuan untuk mengetahui hasil belajar siswa setelah diterapkan model pembelajaran problem solving berbasis demonstrasi pada materi suhu dan pengukurannya. Penelitian ini diadakan di kelas VII SMP Torsina Singkawang. Jenis penelitian ini adalah penelitian kuantitatif dengan bentuk pre experimental design dengan rancangan one group pre-test post-test design. Langkah awal penelitian, siswa diberi pre-test dilanjutkan dengan treatment berupa model pembelajaran problem solving dengan jangka waktu tertentu, langkah akhir diberikan post-test dan lembar respon siswa. Ditemukan bahwa hasil post test lebih tinggi dari hasil pre test yaitu hasil rata-rata 38,69 menjadi 72,60. Peningkatan hasil belajar siswa dihitung dengan menggunakan rumus N-gain dengan hasil nilai sebesar 0,55. Analisis data tersebut menunjukan terjadi peningkatan hasil belajar setelah diberikan perlakuan dengan model pembelajaran problem solving berbasis demonstrasi pada materi suhu dan pengukurannya.
Pedagogia da Autoria
Authors: Moreira de Castro Neves Carmem
Published: July 2020

Digital technology, insofar as it promotes interactivity, integration and media convergence, brought to the contemporary agenda the discussion on a new distance education. This new distance education rejects bureaucratized and inflexible projects that depersonalize course attendants and inhibit innovation and creativity. The proposal put forward in the text is a pedagogy that promotes authoring, based on strategies that view the student as the protagonist of the educational act, respecting the complexity of human beings and their totality and capacity to build significations and generate socially relevant knowledge. This article presents projects that are being developed by the Education and Culture Ministry Distance Education Secretariat, using authoring pedagogy. These projects seek to foster and translate numerous responses from individual and collective actors motivated to explore, analyze, contextualize, deepen, and expand their own view and experience with a given issue.
Особливості відбору баскетболістів на етапі спеціалізованої базової підготовки
Authors: Bezmylov Nikolay , Shynkaruk Oksana , Zhigon Shao
Published: July 2020

Ключовий фактор ефективності процесу багаторічного відбору та спортивної орієнтації в баскетболі – на- явність інформативних критеріїв і показників, які відображають довгострокову перспективу юного спортсмена. Мета статті – проаналізувати критерії й особливості відбору баскетболістів на етапі спеціалізованої базової підготовки. Результати. Складність відбору в ігрових командних видах спорту пов’язана з тим, що в підлітко- вому віці зміст гри починає наближатися до умов спорту вищих досягнень. Перші 5–8 років присвячені пере- важно фізичній та технічній підготовці. Складні тактичні взаємодії, під час яких розкривається потенціал молодого гравця, збільшуються в навчально-тренувальному процесі в 14–17 річному віці. Спортсмени, яких за антропометричними, фізичними й технічними показниками вважали найперспективнішими в дитячому віці, утрачають свою перевагу над однолітками. Установлено, що критеріями для оцінювання спортивної обдаро- ваності баскетболістів і подальшого відбору в рамках багаторічної системи спортивної підготовки рекомен- довано використовувати тести та окремі показники, які характеризують рівень фізичної й технічної підготовле- ності баскетболістів. При цьому в процесі відбору майже не враховуються важливі ігрові здібності баскетбол- лістів, такі як ігровий інтелект й інтуїція, здатність до прийняття правильних рішень в умовах напруженої змагальної діяльності, уміння «бачити» майданчик та інші специфічні якості, які мають вирішальне значення на рівні спорту вищих досягнень. Практично всі рекомендовані в спеціальній літературі тестові завдання для визначення спортивної обдарованості баскетболістів мають допоміжний характер. Висновки. Під час відбору баскетболістів на етапі спеціалізованої базової підготовки та на інших етапах багаторічного вдосконалення потрібно враховувати рівень прояву специфічних ігрових здібностей баскетболістів, які не мають об’єктивно метричних одиниць вимірювання й потребують професійного експертного оцінювання.