bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety and Effectiveness of Platelet Rich Plasma versus Hyaluronic Acid Injection in Pain Management of Hip Osteoarthritis
Authors: S Arefin M. , M Alam M. , A Haque M. , A Islam S. , U Rahman A. , M Akhtaruzzaman A. K.
Published: May 2022

Background: Platelet rich plasma therapy is a simple, low cost and minimally invasive method that provides a natural concentrate of autologous blood growth factors that can be used to enhance tissue regeneration (1). Recent evidences have shown that Platelet Rich Plasma Therapy can be helpful as an osteoarthritis (OA) therapeutic tool by intra-articular injection (2). Hyaluronic acid (HA) is widely used therapy for relief of OA pain and stiffness by intra-articular injection. In addition, there is a sufficient evidence for being significant disease modifying effects. Objectives: The aim of the study was to compare the clinical efficacy of Platelet Rich Plasma with that of hyaluronic acid viscous supplementation. Methods: This study included forty patients with hip osteoarthritis. These patients were selected from the Out Patient Department (OPD) of Dhaka Pain Management Center (DPMC) and Ava Pain & Intervention Center (APIC), Dhaka, Bangladesh during the period from January 2020 to December 2020. Patients were randomly divided into two groups. The first group consisted of 20 patients treated by using intra-articular injection of 2 ml autologous Platelet Rich Plasma Therapy. The second group consisted of 20 patients they were treated by using intra-articular injections of low molecular weight (hyaluronic acid [HA]) (32mg/2mL) of HA (HA group). All patients received 3 injections with one week interval (3) For Follow up: The subjective clinical outcome were measured at baseline, 1, 3, 6 and 12 months after the last treatment dose using the Visual Analog Scale (VAS) (5). Results: The Platelet rich plasma and Hyaluronic Acid groups showed an improvement, with significant difference between the two groups. However after 6 months follow up there was significant improvement in Platelet Rich Plasma Therapy group than HA group (P<0.005). The follow up after 12 months reveled subsided improvement than that was at 6 months. Nevertheless, this subsidence was less in Platelet ...
Sinais e sintomas no manejo de feridas em cuidados paliativos
Authors: Oliveira Pedro Gonçalves de
Published: May 2022

Cada vez mais pessoas morrem de doenças crônicas, levando a uma crescente demanda e provisão de cuidados paliativos. Esse tipo de assistência objetiva promover o alí­vio da dor e de outros sintomas que geram sofrimento e deve incluir as investigações necessárias para sua melhor compreensão e abordagem. É importante considerar o fato de que feridas podem acompanhar esses processos e que a qualidade de vida de um paciente pode ser melhorada ou, no mí­nimo, mantida pelo controle dos sinais e sintomas. Sendo assim, o objetivo deste trabalho foi apresentar e discutir aspectos gerais relevantes sobre sinais e sintomas no manejo de feridas em cuidados paliativos. Trata-se de uma revisão narrativa da literatura que abrangeu o perí­odo compreendido entre 1998 e 2018. Foram utilizadas as bases LILACS, SCIELO e PUBMED, empregando-se os seguintes descritores em saúde: cicatrização de feridas; cuidados paliativos e sintomas. Foram apresentados aspectos gerais relativos a sinais e sintomas no manejo de feridas em cuidados paliativos. A abordagem centrada no paciente e um programa efetivo para controle de sinais e sintomas de feridas em cuidados paliativos podem apresentar inúmeros benefí­cios ao paciente, otimizando seu status funcional, qualidade de vida e dignidade perante a perspectiva de terminalidade.
Percepção dos enfermeiros na terapia de feridas: Tratamento e coberturas
Authors: Barbosa Aliny , Franzolim Rosa Alice de Fátima , Oliveira Pedro Gonçalves de , Castilho João Cezar
Published: May 2022

O objetivo deste trabalho foi avaliar o conhecimento dos enfermeiros no cuidado e tratamento de feridas nas instituições de saúde do municí­pio de Campinas e regiões vizinhas. O enfermeiro atua diretamente na escolha das técnicas ideais e de coberturas que serão utilizadas para promover um ambiente que viabilize a rápida reparação tecidual. A metodologia aplicada incluiu revisão bibliográfica sobre feridas e pesquisa de campo por meio de entrevista auxiliada pela aplicação de questionário com questões abertas e fechadas sobre a avaliação e manejo de feridas. Após coleta e análise dos dados, estes foram confrontados com as informações disponí­veis na literatura e pesquisas referentes ao tratamento de feridas. Os resultados permitem inferir que os enfermeiros realizaram suas escolhas com base no conhecimento técnico-cientí­fico, pautados na etiologia das feridas. No mesmo sentido, é possí­vel afirmar que o conhecimento dos enfermeiros entrevistados revelou-se de grande relevância tanto para o manejo das lesões, quanto para a promoção da assistência adequada.
Pele de tilápia, curativo biológico, uma alternativa para queimaduras
Authors: Pereira Flávia de Campos Maia , Silva Cleide Aparecida da , Bonfanti Ana Paula de Freitas
Published: May 2022

A assistência ao paciente com queimadura sempre foi um desafio para o profissional da área da saúde, um tipo de lesão que provoca marcas além da pele, pode provocar estigmas sociais e grandes impactos econômicos. Frente ao problema, a busca de alternativas ao enxerto de pele e aos curativos de alto custo, pesquisadores brasileiros iniciaram pesquisas com o uso da tilápia com repercussões mundiais. O objetivo deste estudo é divulgar o tema para ampliação e melhor conhecimento do novo curativo biológico apresentado. Foi realizada uma revisão bibliográfica integrativa a partir de bases cientí­ficas fidedignas. Foram encontrados estudos reforçando a eficácia do uso da pele da tilápia, bem como seus benefí­cios, caracterí­sticas histológicas e testes em humanos. Acreditamos que a pele da tilápia é uma inovação brasileira e deve ser adotada como mais um legado para í  assistência aos queimados e em ouras áreas da cirurgia plástica.
Cateterismo intermitente: uma nova geração de cateteres hidrofí­licos
Authors: Dionisio Paulo Sergio , Sousa Ana Lí­gia Martins , Cavazana Carla Paladini , Seifert Silvia Karina Moreira , Oliveira Franciele de Freitas de
Published: May 2022

O funcionamento efetivo do trato urinário inferior no ciclo miccional depende da ação sinérgica da bexiga e do mecanismo esfincteriano uretral, ambos coordenado pelo sistema nervoso central e periférico.
Perfil clí­nico do portador de úlcera venosa: uma revisão integrativa de literatura 2010-2018
Authors: Queiroz Bernardo Rebecca Gabriela , Freitas Carvalho da Silva Larissa , Farinha Vieira Leticia Gizelle , Monteiro Mendes Marcelo
Published: May 2022

As úlceras venosas representam um sério problema de saúde pública, elas são responsáveis por significativos í­ndices de morbidade e mortalidade e também são a causa de lesões prolongadas que demandam um longo tratamento complexo. Além de serem recorrentes, incapacitantes e repercutirem de forma severa na vida dos portadores. Objetivo: Identificar e descrever o perfil clí­nico dos pacientes com úlcera venosa incluindo também a prevalência de idade e sexo. Metodologia: Estudo com abordagem descritiva com aspecto qualitativo, tipo Revisão Integrativa de Literatura. Resultados: Através da pesquisa realizada, foram selecionadas 22 produções cientí­ficas, dentre elas 17 artigos cientí­ficos e 5 teses, abordando sobre o perfil clí­nico dos portadores de úlcera venosa. Conclusão: Os resultados deste estudo reforçam a predominância das úlceras venosa na população feminina, idosa, com comorbidades associadas como hipertensão arterial sistêmica, diabetes mellitus, insuficiência venosa crônica e sobrepeso/obesidade, lesões localizadas na zona 2, durante um perí­odo maior que 6 meses, com pequena quantidade de exsudato seroso, sem odor, prevalecendo tecido de granulação e esfacelo.
Hardware Implementation of IoT based Smart Power Protection Unit for Power Distribution System
Authors: Uma Shankar G. , Chitra S.
Published: May 2022

Power protection devices are deployed to protect assets while also providing a steady supply of electricity. The importance of a power protection unit is that it maintains the security of electrical consumers connected to the electrical supply grid by interrupting the power supply in the case of a variety of problems, including overvoltage, overcurrent, leakage current, and electrical arc. Power protection systems with Arduino uno board leads to attain decreased efficiency, increased cost of internal connectivity and poor network reliability. IoT based power protection devices can overcome these difficulties in a better way. This research provides a power-system protection device that can be integrated into smart environments and is based on Internet-of-Things technology. The proposed system improves safety by rapidly disabling the power supply in the event of a disaster such as a leakage current, an electrical arc, a power surge, or an overcharge, and it is designed to be incorporated into intelligent devices such as smart buildings or green infrastructure to protect electrical equipment.
THE AVAILABILITY OF INFORMATION SCIENCE AND RECOMMENDATIONS TO THE DEVELOPMENT OF COMMUNITY INFORMATION SCIENCE, (WITH SPECIAL REFERENCE TO INDIAN STATES)
Authors: Dr. Manjunatha S
Published: May 2022

In the modern era information science is very essential to get information and statistics of various departments like education, agriculture and the service sectors, In the Indian context, majority of Indians are living in rural areas and working in Agriculture or small scale industries. In India 74.3 percent population lives in rural areas and 25.7 percentage population lives in urban areas. The agriculture sector provides livelihood to 64 percent. For the development of the country, it is very important to emphasize on the development of rural community. Information is one of the most important factors for the process of development of any sector especially rural community. Information is birth right of a human being irrespective to the class and creed he/she belongs to. Particularly in a big country like India, information needs to be shared and disseminated to all the citizen of the country. So far, libraries and professionals have been serving the population in a closed framework which needs to be changed in the changing context beyond physical buildings to virtual environment. Anything and everything can be found over Internet and this environmental change has changed the information seeking behaviour of the users.
KEY WORDS: Community Information Science, Digitalisation Benifits In The Growth Of Library Science In India.
How can Entrustable Professional Activities serve the quality of health care provision through licensing and certification?
Authors: Ten Cate Olle
Published: May 2022

This paper about Entrustable Professional Activities (EPAs) was solicited to support the discussion about the future of licensing within the Medical Council of Canada. EPAs, units of professional practice to be entrusted to learners or professionals once they have shown to possess sufficient competence, were proposed in 2005 to operationalize competency-based postgraduate medical education and have become widely popular for various health professions education programs in many countries.
EPAs break the breadth of competence for license down to units of practice that can be overseen, assessed, monitored, documented, and entrusted. EPAs together may constitute an individual's portfolio of qualifications, and define a scope of practice. A medical license and a specialty certification can then be defined as the required combination of EPAs for which one is qualified at any specific moment in time. That 'snapshot' could change over time and reflect the professional development of the individual, both in their competence and in their privileges to practice. Micro-credentialing and digital badges might become an adequate option to show-case one's scope of practice at any time and operationalize the idea of a dynamic portfolio of EPAs.
Effects of Lifestyle Change on Sustainability for ‘Reforming the Indian Economy’
Authors: Mandal Dr. Chameli
Published: May 2022

From 19th century it has become our slogan that economy must develop following a sustainable path- a path of sustainable society and sustainable environment which are very much interdependent to each other. The linking parameter between the two interrelated concepts of sustainability is the sustainable lifestyle. Objective of the study is to assess the behavior of lifestyle change and sustainability of the secondary school students and the correlation between the two. The sample comprises 150 students, both boys & girls ranging in age from 15-17 years and studying from various secondary institutions under WBBSE in West Bengal. In our study we have considered stratified purposive sampling due to short time period. Two validated questionnaire vetted by experts and researchers in measurement and research was used as an instrument for data collection and analyzed by employing quantitative research approach. In the study we have considered two categories of lifestyle namely positive lifestyle and negative lifestyle. The study reveals that a different category of lifestyle has some effects on sustainability. Also it has been found that a relationship exists between lifestyle change and sustainability. Understanding the effects of lifestyle change on sustainability has become a challenging issue now days. Students are the future of world so if they are in the habit of positive lifestyle then it would not take much time to turn our society into a sustainable society and this indirectly reform the economy.
Generation of Exactly Solvable Potential from Trigonometric Scarf Potential in D-dimensional Space
Authors: Saikia Nilamoni
Published: May 2022

Exact bound state as well as scattering state solutions of Schrodinger Green’s function equation is presented for constructing hyperbolic class of exactly solvable quantum systems are obtained in D-dimensional space, using extended transformation method. In the current literature the exact solution to the hyperbolic Scarf are written in terms of Jacobi polynomials and these polynomials are referred to Romanovski polynomials. The normalizability of bound state solutions of the generated exactly solvable potential are discussed.
Företrädare och ställföreträdare. Om sociala handlingspositioner
Authors: Eriksson Björn
Published: May 2022

Vertreter and Stellvertreter: On acting from a positionThe article is part of an attempt to build a structural theory of interaction. It tries to identify a limited set of acting positions - Vertreter, Stellvertreter and personal acting. The theoretical point concerning these acting positions is that each demand a stable set of acts, and work from different logics. This stability is unmoved by such things as changes in the identity or in the preferences of the actor. The actor must subordinate himself under the logic of the position if he is to be able to co-operate with other actors. The Stellvertreter acts in another’s name, alieno nomine agere, while the Vertreter answers for another’s acts. In many situations, an actor may act as the one or the other - the priest acts in the name of God and answers for the acts of the church, which is problematic since the two may be opposed, even antagonistic, to each other.
Patriarchal values
Authors: Shaditalab Jaleh , Mehrabi Rana
Published: May 2022

Patriarchal values: girls are more apt to changeHow has the family value system changed between generations, especially when taking into account the gender dimension? This article presents some results from a study carried outin 2007 in one village of the Gourani tribe where the people are followers of Ahle Hagh in Islamabad Gharb (west of Iran).The differences between generations (those born and raised before and after the Islamic Revolution) in patriarchal values in the family are statistically significant. The older generation opts for the man of the family to make most of the decisions; on children’s education, marriage, naming, the families expenditure, the place for residence, the social network of the family and even the number of children. The younger generation has a different value system and it has moved towards a more egalitarian type of family.With the gender variable included in the findings we see that although the values of the younger male population have evolved toward a less patriarchal decision making structure inthe family, the degree of changes among the young women is much higher.Looking into the preferences for male sex for the first child as well as a larger number of boys in the family, the difference between generations is significant. However data on the differences analyzed with the gender variable proves that the changes concerning the equality of sexes are mainly due to drastic changes in the young women’s value system. That is, the male population, young or old, still prefer to have a boy as their first born and to have more sons in the family. But the young female generation in the rural area sees less difference in having boys or girls in the family.It is concluded that reforms in the old value system is an evolving process of everyday life and that the girls are the main social force for change.
The Survivability of Swedish Emergency Management Related Research Centers and Academic Programs
Authors: Neal David M.
Published: May 2022

The Survivability of Swedish Emergency Management Related Research Centers and Academic Programs: A Preliminary Sociology of Science AnalysisDespite being a relatively safe nation, Sweden has four different universities supporting four emergency management research centers and an equal and growing number of academic programs. In this paper, I discuss how these centers and programs survive within the current organizational environment. The sociology of science or the sociology of scientific knowledge perspectives should provide a theoretical guide. Yet, scholars of these perspectives have produced no research on these related topics. Thus, the population ecology model and the notion of organizational niche provide my theoretical foundation. My data come from 26 interviews from those four institutions, the gathering of documents, and observations. I found that each institution has found its own niche with little or no competition – with one exception. Three of the universities do have an international focus. Yet, their foci have minimal overlap. Finally, I suggest that key aspects of Swedish culture, including safety, and a need aid to the poor, help explain the extensive funding these centers and programs receive to survive.
Visible persons, invisible work?
Authors: Lydahl Doris
Published: May 2022

Visible persons, invisible work? Exploring articulation work in the implementation of person-centred care on a hospital wardRecently, many initiatives promoting a holistic view of the patient have been developed. In the last 20 years, different models and frameworks have been advanced to operationalize these different forms of holistic care. This article focuses on one specific case of holistic person-centred care, using the sociological theories of articulation work and invisible work to investigate the efforts involved in sustaining its realization. The article builds on a small ethnographic study conducted at a ward in a Swedish hospital implementing person-centred care. Following a nurse, and her patient, through a ‘person-centred’ admission process and its subsequent procedures, it is argued that person-centred care depends on nurses performing many new tasks which are rarely recognized and appreciated. Secondly, it is argued that nurses are continually asked to do what Anselm Strauss defined as articulation work, coordinating between these different new tasks and established duties. Thirdly, the article discusses the tensions arising when implementing a formalized model of care, which builds on a critique of standardization and objectification, and the work that is excluded and invisible in such routinized operationalization. Finally, it is concluded that while the successful implementation of person-centred care is often argued to rely on the willingness of nurses to surrender old habits, it seems rather to hinge on the skilled inventiveness of these nurses and their ability to overcome the practical difficulties they encounter.
The ”People’s home” is falling down, time to update your view of Sweden
Authors: Therborn Göran
Published: May 2022

Swedish society is changing profoundly. The egalitarian, solidaristic ”People’s Home”, which has attracted widespread progressive admiration internationally, is being eroded and dismantled. The political economy of this process, since the turn of the l980s, is highlighted; a process which includes a major, if not complete, substitution of a capitalist market of social provision for a welfare state, and of a stock market-driven capitalism for a full employment work economy. Some of its direct inegalitarian consequences are indicated, as well as unintended ones of petty corruption, cronyism, and swindle. The socio-political dynamics of the turn is briefly outlined.
Lone mothers with low income face obstacles to practice their mothering
Authors: Roman Christine
Published: May 2022

Sweden stands out as a forerunner in the development of gender equality and family dynamics. To deepen the knowledge on power distribution and gender dynamics of couple relations, we investigate how women and men’s childbearing intentions influence actual childbearing behavior. The Young Adult Panel Study (YAPS) has information on both partners’ childbearing intentions in 2009, which we follow for five years with register data on childbearing. The results indicate that women’s childbearing intentions are more important than men’s intentions in determining actual childbirths.
Education: Family resources help girls more than boys when it comes to mental-health problems
Authors: Brännlund Annica , Edlund Jonas
Published: May 2022

Research has established that school performance relates: (i) negatively with poor mental health during childhood and (ii) positively with family socioeconomic resources. In this article, we examine the potentially moderating effects of family resources on the relationship between school performance and poor mental health, using register data covering all children born in Sweden in 1990. The dependent variable is graduation from upper secondary school. We perform separate analyses for girls and boys. Our results indicate that compensatory effects of the socioeconomic resources of the family on the risk of graduation failure among those with poor mental health is more pronounced among girls compared to boys.
Young people in suburbs feel discriminated, but hopeful
Authors: Dahlstedt Magnus
Published: May 2022

Based on research in Swedish multi-ethnic areas, this paper examines discourses of unrest among youth in multi-ethnic, tower-block suburbs. While there is a focus on the mechanisms of racialized social exclusion among the youth, the preoccupation among local actors including social workers, police, principals and representatives of NGOs as is with the ‘area of exclusion’ itself as causing the problems of urban unrest. Such problematizing highlights broader policy changes in Sweden, where the main responsibility for welfare is put on the individual, rather than on the collective and the state.
An interview with Bridget Anderson
Authors: Sager Maja
Published: May 2022

In the interview Anderson is discussing the migrant as a political and analytical category and the need to think across the categories of citizen and migrant to challenge the exclusion of the latter group – but also to highlight the interconnectedness of processes of social exclusion and marginalisation across the citizen/non-citizen divide. Anderson also reflects on current developments in Europe and the UK in regards of Brexit and the growing support for fascist and extreme right populist movements and political projects.
A Swedish culture of advocacy?
Authors: Arvidson Malin , Johansson Håkan , Meeuwisse Anna , Scaramuzzino Roberto
Published: May 2022

This article sets out to identify a culture of advocacy that has come to characterise Swedish civil society, formed around a long-standing tradition of close and cordial relations between civil society organisations, popular movements, and state and government officials. We argue that Swedish civil society organisations (CSOs) have been allowed to voice critique against public actors and policies and are expected to do so. Based on a large survey of Swedish CSOs, this study contributes unique data on what type of advocacy strategies CSOs practise, and the range of advocacy strategies that organisations employ. The analysis also explores norm-breaking behaviour, such as holding back criticism of public authorities. The results reveal a complex picture of a culture of advocacy: we find patterns of intense political activity among organisations that admit they hold back in their criticism of public authorities and the use of a wide range of advocacy strategies. The article contributes to and challenges established advocacy research and analyses established patterns of organisations’ advocacy activities with the symbolic acts of breaking norms, as an analytical approach for the study of advocacy strategies in general and advocacy culture in particular.
Digital media and the acceleration of resistance
Authors: Brown Craig
Published: May 2022

This article is concerned with providing empirical evidence relating to the use of digital media and resistance during the so-called Arab Spring events. These events have been widely acknowledged as a case where digital media significantly contributed to the successful attainment of movements’ objectives. The use of such innovative technologies has been tied to the characteristics and, ultimately, the ends of these movements, with their ‘youthful’, ‘leaderless’ and ‘spontaneous’ nature reflecting Western-orientated practices. However, the analysis presented here utilises interview data obtained from participants in the 2010/11 Tunisian Revolution, detailing their perspectives and explanations of digital media’s role. The data and analysis show that while such technologies were a useful tool, their prominence has been exaggerated and offers a flawed understanding of the events. Rather, the social change being pursued during the Tunisian revolution was profound. Therefore, the deeper implications of the common emphasis on digital media in the literature is explored, with Rosa’s (2015) assessment of social acceleration being informative for elaborating on the nuances of these technologies’ use during the 2010/11 events.
Recensionsessä
Authors: Ståhl Christian
Published: May 2022

Denna text är en recensionsessä av en nyutkommen bok av Rafael Lindqvist, Aktivering och medikalisering i sjukförsäkringen: Det sociala medborgarskapets förändrade innebörder (2019), och ska läsas som en sidobelysning till de resonemang som förs i boken. Jag kommer att särskilt fokusera på begreppet arbetsförmåga. Arbetsförmåga är ett centralt begrepp i det svenska sjukförsäkringssystemet som många medborgare och professionella behöver använda och förhålla sig till. Det kan dock ha olika innebörd både i begreppslig mening, och i de olika system där det används. Dessa system är ofta politiskt styrda, vilket innebär att begreppet också underordnas de normsystem och sociala kontexter som råder i dessa system; det är i den processen som det används och ges betydelse. Jag kommer att argumentera för att arbetsförmåga är ett paradoxalt begrepp i den svenska sjukförsäkringen, eftersom det samtidigt kan betraktas som såväl avmedikaliserat som strikt biomedicinskt.
Probiotic Effects Upon Resilience And Recovery
Authors: Archer Trevor
Published: May 2022

The presence of microbiota, functionally in the role of therapeutic probiotics, exerts fundamental actions upon the induction, shaping, training, and function of the host immune system, e.g. among humans. In exchange, the host immune system has largely evolved as a means to maintain and develop the symbiotic relationship of the host with these highly diverse and evolving microbes, such as yeast cells. When operating optimally, this immune system-microbiota alliance allows the induction of protective responses to inflammatory agents and pathogens and the maintenance of regulatory pathways involved in the preservation of tolerance to innocuous antigens thereby promoting both cellular and functional resilience. Resilience presents the process(s) through which individuals are enhanced in their adaptation to their resistance to adverse conditions and enabled in their capacity recover from them. Resilient individuals possess a different immunophenotype from those presenting stress susceptibility and disease-propensity.
Covid-19 Vaccination Responses In A Cohort Of Patients With Immunodeficiency- Clinical Experience From One Centre
Authors: Dziadzio Magdalena
Published: May 2022

Vaccinations against COVID-19 first became available in the UK in December 2020 [1] and are protective against severe disease and death [2]. Patients with primary and secondary immunodeficiencies are at increased risk of mortality and morbidity from COVID-19 disease [3-4]. The efficacy of vaccines in individuals defined as extremely vulnerable or vulnerable is not yet well known and data is being collected; patients with a weakened immune system might not develop robust immune responses post-vaccination and therefore remain at risk of COVID-19 disease [5-7]. Vaccine responses are an integral part of the investigation of patients with suspected immunodeficiency attending immunology clinics.
Resilience Buttress Facilitating Recovery
Authors: Archer Trevor
Published: May 2022

Resilience, a process favoured by individual qualities that have been well-documented within mental health care parameters of stress and trauma, including personal control, intrinsic motivation, empowerment positive affect, optimism, social support, and the propensity for physical exercise implies a lifestyle that permits individuals to adapt, even thrive, within adverse conditions and to recover from those circumstances
Research Progress Of Sc R N A - Seq In The Field Of Laryngeal Cancer And Other Tumors
Authors: Hong Guo
Published: May 2022

The scRNA-Seq has become a powerful tool for unbiased and systematic characterization of cells in a given tissue. Indeed, the application of scRNA-Seq in patient tumors has identified multiple cell subpopulation and highlighted intercellular connections in the tumor microenvironment. In this paper, we review the progress of research on scRNA-Seq in the field of laryngeal cancer and other tumors in the last decade, which is of interest to explore the pathogenesis of laryngeal cancer and other malignancies.
A Puzzling Crusted Scabies On The Nipple Of An Immunocompetent Woman
Authors: Mezni Line
Published: May 2022

A lot of physicians are unenlightened with the wide spectrum of clinical manifestations that can evolve in the nipple and areola skin. Due to the importance of this area of the body, cosmetically, sexually, and functionally a deep understanding of its disorders is crucial. This case has been reported under crusting and watery sticky drainage from the right nipple secondary to crusted scabies in a healthy patient.
Results Of Clinical Testing Of Infanetim Technology Silver Line Toothpaste
Authors: Igorevich Shabalkin Pavel
Published: May 2022

Aim: To assess the impact of daily use of INFANETIM Technology® SILVER LINE hygienic toothpaste in adult volunteers and patients with a history of cancer on the risk of acute respiratory viral infections (ARVI), and its preventive effect on cancer relapse.

Patients and Methods: We conducted a controlled clinical observation with the participation of volunteers over 50 years of age, including those with a history of cancer. 612 volunteers were randomly assigned to use INFANETIM Technology Silver Line hygienic toothpaste or another regular hygienic toothpaste daily over the course of 2 years.

Results: During clinical follow-up, the incidence of acute respiratory viral infections per 612 volunteers who completed the full program was 64 in the INFANETIM Technology® group versus 229 in the control group (p=0.02; 95% CI 23-31%). In the study group, 9 cases of cancer relapse were registered among those who had a history of cancer, in the control group during the observation period, cancer relapse developed in 23 participants (p=0.046; 95% CI 27-49%).

Conclusions: Daily oral hygiene with the use of a specialized toothpaste INFANETIM Technology Silver line reduces the risk of ARVI by more than 3 times (p=0.02; CI 23-31%) and reduces the risk of cancer relapse.
Causes Of Desertion Of Diabetes Preventive Programs Aimed At Relatives Of Patients With Type 2 Diabetes
Authors: Hernández-Jiménez Sergio
Published: May 2022

Purpose: First-degree family members of patients with type 2 diabetes have a higher risk of developing diabetes. Attendance in a diabetes prevention program is essential to implement prevention strategies. However, many relatives drop out. Identifying the causes behind the program abandonment is necessary to improve attendance adherence.

Methods: We reviewed six different databases for causes of treatment abandonment in prevention programs for type 2 diabetes published between 1980 and 2020. Eleven articles met inclusion criteria and varied in sample size, ethnicity, gender, age of the participating patients, and length of follow-up. Causes of abandonment were categorized into social, biological, lifestyle, and emotional.

Results: Sample sizes of the selected studies ranged from 143 to 128,520 subjects. The main barriers were age, economic difficulties, ignorance about risk factors, family history of diabetes, living in public housing, marital status, comorbidities, and low consumption of fruits and vegetables. Physicians' attitudes toward prediabetes screening were also a barrier.

Conclusion: People at risk of developing diabetes face multiple barriers to preventing the development of this disease. During the research, the variety of reasons causing dropouts in prevention programs was great and diverse.
Male Hypogonadism And Osteoporosis: A Systematic Review
Authors: Oduwegwu Eucharia
Published: May 2022

Background: Male hypogonadism can be defined as a disorder caused by decreased testosterone levels leading to low sperm count, multiorgan dysfunction and inadequate quality of life. Osteoporosis is defined as a debilitating condition which causes loss of bone mass and structure leading to considerable risk of fragility fracture and increased mortality. About 6% of men and 21% women between ages 50 to 84 years suffer from osteoporosis, changing the lives of 27.6 million males and females in the European Union (EU) in 2010. Osteoporosis is responsible for>8.9 million fractures yearly around the world, about 1000 cases an hour. The prevalence of osteoporosis increases as the population advances in age. Fracture risk increases in those with reduced bone mineral density(BMD) than those with osteoporosis.Although the risk of osteoporotic fracture is less in men than women however men are twice at risk of dying from the consequences of such fractures than women. World Health Organization (WHO) defined osteoporosis as a BMD of 2.5 standard deviation (SD) or more below the mean in young healthy female, with a T score of-2.5 or lower. The American college of physicians recommend early evaluation of men<65 years old who are at high risk of osteoporosis using Dual energy x-ray absorptiometry (DXA) scan.

Objective: The aim of this review is to conduct a systematic review of available literature to evaluate epidemiology and risk factors for osteoporosis in men. The focus of this work was to critically review evidence related to impact of hypogonadism on bone health in men.

Methods: A thorough search of different electronic databases was done including PubMed, google scholar, Cochrane database and FINDIT in the university of South Wales library and data collected.

Results: Some studies reported that only 4.5% men were treated for osteoporosis compared to 27% women. The annual death rate was 32% in men and 17% in women. In 1-5 years follow up, only 27% men were on any form of therapy while 71% women were on treatment. A study of 241 men who received 10mg of alendronate daily for 2 years compared to placebo showed a notable rise in BMD, and a notable decrease in fracture of the vertebra was documented with OR of 0.10, CI; 95%; 0.00-0.88. A study of 284 men treated with risedronate showed successful increase in BMD in contrast to placebo. Obesity is one of the most common causes of male hypogonadism, usually associated with normal or reduced follicle stimulating hormone (FSH), luteinizing hormone (LH) and low testosterone levels.

Conclusion: The burden of osteoporosis is severe and is shown in the increased level of disability and death in the affected patients and yet only a small number of men are given adequate treatment. Recognition and treatment of male hypogonadism and osteoporosis has received some attention lately, however, it remains under detected and under treated, much needs to be done in investigating for hypogonadism in men with fragility fractures.
Early Invasive Ventilation And Early Extubation To Niv– The Management Of Covid-19 Patient With Severe Acute Respiratory Failure
Authors: Yahya Salman
Published: May 2022

The covid-19 pandemic since its inception has reshaped many healthcare practices. One of the most severely affected specialty is intensive care and multiple strategies have been applied to deal with the severe covid-19 related pneumonia. This case report focuses on early invasive ventilation strategy versus delayed invasive ventilation strategies and early extubation and subsequent post-extubation support with Non-invasive ventilation strategies.
Assessment And Evaluation Of The Efficacy Of Planned Teaching Project On Basic Life Support In Terms Of Knowledge And Skill Among Staff Members Working In Mall
Authors: Solanki Srishty
Published: May 2022

Background: Cardiac arrest is a big challenge for the people’s wellbeing both in and out of the hospital. Currently to ensure the maximum level of care for each patient who have met with cardiac arrest previously, we should efficiently interpret the resuscitation process into clinical care and to improve resuscitation after effect. Effective basic life support given immediately after cardiac arrest can improve a victim’s chance of survival.

Methods: Quantitative research was approached using descriptive design in the study. The setting of the study was at DLF Mall of India, Noida. 60 specimens were chosen by convenient sampling method. Two tools were used, Structured Knowledge Questions and Observation check list. Descriptive and inferential statistics was done by using data examination.

Result: Data showed the mean after test knowledge score was (33.00) of staff members which was more than their mean before test knowledge score (9.03) having a mean difference of 23.967. The mean after test skill result(14.52) of staff members were more than their mean before test skill result (1.10) having a mean difference of 13.417. The r value was found to be 0.248 which signifies there is a weak positive relationship between knowledge and skill of staff members. There were no significant association found in among mean before test knowledge result and skill scores like age, educational qualification, certification in basic life support.

Conclusion: The observation shows that the scheduled teaching project was effectual during building up knowledge and skill of staff members related to basic life support.
The Balloon Paradox - A Case Series
Authors: Mehta Haresh G
Published: May 2022

Background: Once regarded as the final frontier of coronary intervention, the success rates of chronic total occlusion (CTO) angioplasties have been steadily increasing. Understandably, the use of specialized hardware makes this an expensive undertaking. We propose a novel, creative, and inexpensive method to address this issue, by simply using a balloon, differently.

Case summary: While specialized wires facilitate crossing the CTO segment, lesion preparation remains a challenge. Vigorous manipulation of routine PCI balloons for lesion entry can be detrimental. Tapered micro-catheters are successful as they rely on rotational forces and maintain guide stability.

Newer CTO PCI balloons have crossing profiles comparable to most micro-catheters. Hence, applying rotational force on these kink-resistant balloons, facilitates their use as low-cost micro-catheters. We employed this technique, with surprisingly good results. While not all the lesions could be successfully crossed, the financial implications of this study on a small cohort of patients are, in our humble opinion, quite significant.

Discussion: The aforementioned method uses inexpensive hardware, which can be used further, for lesion preparation. The balloon functions on the principle of a Tornus catheter, burrowing deep into the occluded segment. While this technique has higher failure rates in heavily calcified lesions, we were able to cross the lesion in a fair number of cases. We believe this technique, which is safe and simple, can reduce the dependence on complicated and expensive CTO hardware in a significant number of cases.

Learning Points

1. Balloon can be used like a corsair and tornus in balloon uncrossable lesions

2. It provides a safe and inexpensive way to cross such lesions.
Two Cases Of Atrial Aneurysms And Pectinate Muscle Dysplasia In Childhood
Authors: Albanese Sonia B
Published: May 2022

Primary atrial enlargement is a rare condition that can involve either the right or left atrium or both. Two such cases are described, and pathogenesis and treatment considerations are reported, concluding that surgical treatment does not necessarily exclude the possibility of late recurrence of supraventricular arrhythmias.
Abdominal Examination Of Children With Telemedicine In Covid-19 Pandemic
Authors: Bittmann Stefan
Published: May 2022

The first application of telemedicine was a banal event on March 10, 1876, when British inventor Alexander Graham Bell accidentally spilled acid on his suit while working on his patented "telephone apparatus" and used the device to call his colleague Thomas A. Watson, who was present in the next room, for help. If the distance was only a few meters during this first medical emergency or remote call only 130 years ago, telemedicine has developed until today to a tool that enabled the ground personnel of the American space agency "NASA" to provide medical monitoring or care for astronauts located in the thermosphere - in real time.
The Dissimilar Conglomerate - Placental Teratoma
Authors: Bajaj Anubha
Published: May 2022

Apart from trophoblastic placental neoplasms, non-trophoblastic placental tumors are further categorized into primary or secondary non-trophoblastic tumefaction. A frequently discerned category of non-trophoblastic, primary placental tumor is chorangioma discernible in an estimated 1% of gestations. Secondary to a chorangioma, a non-trophoblastic, primary tumor is exemplified by the placental teratoma.
The Early Prostehtic Management Of Hypohidrotic And Anhidrotic Ectodermal Dysplasia: About Two Clinical Cases
Authors: Charfi Nihel
Published: May 2022

Ectodermal dysplasia is a hereditary disorder. Patients with ectodermal dysplasia have ectodermally-derived organs disorders which can affect teeth, nails, hair and sweat glands. Disorders of sweat gland function can be classified into two major groups: hypohidrotic or anhidrotic. Oral findings in patients with ectodermal dysplasia (ED) include markedly reduction in number of teeth (oligodontia or hypodontia), malformed and widely spaced conical-shaped teeth, and underdeveloped alveolar ridges. Other dominant clinical features can be found like very thin hair. The goal of the article is to present the prosthetic management particularities of two patient with hereditary ectodermal dysplasia.
The Remediable Metarteriole - Chorangioma
Authors: Bajaj Anubha
Published: May 2022

Chorioangioma is a benign, non-trophoblastic, vascular neoplasm arising from the placenta. Chorangioma is associated with features such as advanced maternal age, diabetes mellitus, hypertension, preeclampsia, multiple gestations or high-altitude pregnancy. The miniature, asymptomatic chorangioma is incidentally discovered whereas giant chorangioma exceeding >4 centimeters magnitude exemplifies adverse perinatal and foetal outcomes and is associated with intrauterine growth restriction (IUGR), polyhydramnios, preterm labour, arteriovenous shunts, foetal cardiomegaly or foetal heart failure, hydrops foetalis, foetal thrombocytopenia and maternal mirror syndrome. Tumefaction is composed of foetal capillaries circumscribed by stroma and trophoblastic tissue. Foci of tumor infarction, fibrosis, hyalinization, calcification and deposition of hemosiderin pigment are observed. Chorangioma requires a segregation from chorangiosis, chorangiomatosis, inflammatory myofibroblastictumor, Leiomyoma, placental infarct, intervillous thrombus or chorangiocarcinoma. Chorangioma or giant chorioangioma can be suitably discerned with ultrasonography. Treatment options such as draining excessive amniotic fluid or surgical intervention of chorioangioma with laser coagulation and electrosurgical maneuvers may be adopted.
Evaluation on the Basis and Application Performance of a Modified Surface Active Oil-displacing Agent
Authors: Fan Jiacheng , Qu Zhanqing , Guo Tiankui , Qi Ning , Chen Ming , Liu Xiaoqiang , Wand Jiwei
Published: May 2022

The oil development has entered the water flooding stage in Changqing Oilfield. Due to the low reservoir permeability and the high oil viscosity, the water-flooding does not achieved the desired effect. A large amount of oil is retained in the reservoir due to the high water surface tension and oil-water interfacial tension. Currently, the performance of an oil-displacing agent is suitable for Changqing oilfield to mitigate this situation, but with high application cost due to its synthesis in an organic solution. In this study the oil-displacing agent is modified, and an amphiphilic oil-displacing agent is synthesized through aqueous polymerization. With addition of the oil-displacing agent, the surface/interface activity of water and oil changed significantly. The surface tension of water and oil reduces from 69mN/m to 25mN/m and from 21mN/m to 7.8mN/m respectively in the 1500mg/L oil-displacing agent at 60℃, and the oil-water interfacial tension reaches the ultra-low level. In addition, the oil-displacing agent has the good oil emulsification ability, and the emulsion shows stable performance. The core flooding experiment shows that the 2000mg/L oil-displacing agent can increase the oil recovery by 20% compared with the water flooding, and this meets the production needs in the oilfield. Since the oil-displacing agent contains a large number of chelating functional groups, so it can also chelate the heavy metal ions in the reservoir to prevent precipitation with incompatible anions in the injected water.