bluuebunny/crossref_metadata_2025 huggingface dataset:
O Geoparque Caçapava Aspirante (RS) como ponto de partida aos termos sustentabilidade, desenvolvimento, território e o produto territorial do Alto Camaquã
Authors: Silva Michelle Oliveira
Published: September 2022

Este trabalho parte da definição de certos programas no escopo da UNESCO – Organização das Nações Unidas para a Educação, a Ciência e a Cultura – segundo a qual um Geoparque é definido como um território com limites definidos e com área suficientemente grande para dar suporte ao desenvolvimento socioeconômico local. Deve ser ressaltado previamente que as fontes bibliográficas são por enquanto escassas, uma vez que o tema é novo e segue em franco construção teórica. A ideia condutora deste trabalho repousa na percepção de que o Geoparque Aspirante Caçapava preenche os critérios para se tornar efetivamente um geoparque, se apenas considerarmos o potencial do território em questão de se desenvolver endogenamente. Nosso foco é na configuração socioespacial, categoria que engloba termos como geodiversidade, sustentabilidade, desenvolvimento e território. Um fator local relevante é a produção de cordeiro, praticada num território único em termos de paisagem, natureza e cultura humana, de forma a transformar essa produção em um marco territorial, também conhecido como “produto do terroir”. De fato, a produção de cordeiro pode, como este trabalho procura demonstrar, ser o ponto inicial para combinar teoria e práxis, uma vez que ela desponta como o estímulo mais importante e visível para o desenvolvimento local endógeno na região do Alto Camaquã, onde se localiza o Geoparque Aspirante Caçapava.
First year residency in Emergency Medicine in Denmark
Authors: Bentsen Lasse Paludan
Published: September 2022

Background:  Emergency Medicine is the youngest Danish medical specialty, finally adopted in 2017 with the first residents enrolled in 2018. The residency consists of 1 year introduction employment with a primary residency spanning 5 years after the introduction year. The 1-year program consists of different setups of time in certain specialty areas, encompassing the primary specialties internal medicine, abdominal surgery and orthopedic surgery. The education programs can be differently structured, but with the same end qualifications for the resident. We aimed to investigate the different structures of the education programs for the 1st year residency in Emergency Medicine in Denmark.
Methods: All education programs were extracted from the three different medical educational regions in Denmark in March 2020. We reviewed all programs and the following data was extracted: Time in each primary specialty, medical courses, possibility to practice the role of team leader in critical ill patients and education in point-of-care ultrasound.Results: 20 of 21 emergency departments in Denmark employs residents in Emergency Medicine for their 1-year introductory residency. 13 of 20 programs assess patients in internal medicine and abdominal surgery in the same time period. 7 out of 20 has pre-specified time for patients in abdominal surgery. 10 of 20 programs does not have specified time in orthopedic surgery. This is part of the internal medicine period or not specified further. Only programs in The Region of Southern Denmark have pre-specified periods for all three main specialties. 14 of 20 programs present opportunity to participate in medical courses such as Advanced Life Support. Only 3 of 20 programs present opportunity for further education in point of care ultrasound, other than the obligatory focused lung ultrasound and ultrasound guided peripheral access. 7 of 20 programs present opportunity to participate in primary assessment of critical ill patients as team leader or observer, for critical care calls.
Conclusion: The education programs in Denmark for Emergency Medicines 1st year residency varies greatly in both time in major specialties, medical courses, point-of-care ultrasound and training in the role as team leader.
Sucesiones paleobiológicas y sucesiones registráticas (nuevos conceptos paleontológicos)
Authors: Fernández-López Sixto
Published: September 2022

Las sucesivas entidades registradas y los estratos que las contienen pueden ser consideradas como disociables en­tre sí. Interpretando las relaciones tafonómicas evitamos el problema de describir la evolución biológica respecto a una escala que en sí misma está basada en una interpretación de la evolución biológica. Se propone que las nuevas categorías de clasificación paleontológica establecidas en este artículo deben ser llamadas unidades registráticas.
El género Odontochile Haewe y Corda, (Trilobita), en el Devónico Inferior de la Cordillera Cantábrica y el Pirineo
Authors: Arbizu Miguel
Published: September 2022

En el presente trabajo se destaca el interés que tiene el género Odontochile para el estudio del Devónico en el momento actual. Se realiza un análisis de las especies de este género encontradas en el Devónico Inferior de la Cordillera Cantábrica y del Pirineo, dándose algunas precisiones sobre la distribución estratigráfica de las de la primera región. O. spinifera, especie de amplia repartición geográfica, es la única forma común entre los Trilobi­tes devónicos del Pirineo y de la Cordillera Cantábrica, lo que permite realizar la correlación de ambas áreas du­rante el Emsiense inferior.
Management, Communication in the Health Institution
Authors: Vrućan Valentina
Published: September 2022

If we look around, we can easily notice that the world would not function without communication. How could we express our thoughts and what we want unless we say it, show it and touch it? Therefore, the business world could not function without interpersonal communication either, especially in the health institutions. The beginning of the research was based on the hypothesis that communication had to be open for the system to function, and employees satisfied with the working atmosphere and the relationship with the facility management. It was assumed that verbal communication was the most common form of communication, which often resulted in conflicts among health professionals. The research showed that the respondents were aware of the importance of creating effective communication, both within the same health care facility and outside it, especially conversation, assuming that they can convey the most important information in the shortest possible time. The data on formal communication at workplace indicated that employees believe that communication with their colleagues did not have to be formal, because in that way collective work would be more productive and the working atmosphere more pleasant. It is very important for every health care institution to invest enough funds in the activities, such as the health service promotion. Teamwork, health managers and employees contributed to the development of the health institution.
Effect of Core Muscles Strengthening Workouts in Improving the Static Balance of Judo Players
Authors: Soror Aboelwafa Hassan
Published: September 2022

Core muscles have multiple benefits for athletes and non-athletes, such as their importance in improving motor performance and preventing injuries. Judo players perform various movements during training or matches, such as bending, rotation, and flexion, which depend heavily on the muscles around the torso as well as the balance requirements during throwing to reach the optimal position of the throw. This study aimed to verify the effectiveness of intense training during the preparation period to strengthen the core muscles on the static balance of the judo players. In total, 24 judo players participated in the study to form two groups: an experimental group (12 players), who were trained via intense core muscle workouts (8 exercises) according to specific instructions (three times per week / 6 weeks), and a control group (12 players), who were trained on various muscle groups (three times per week / 6 weeks). The Flamingo test (European Fitness Test–Euro Fit) was applied to measure the static balance of the players (pretest–posttest). The results showed an improvement in the static balance for both groups, the comparison between the two groups showed the experimental group indicated statistically significant changes (p 0.05) than the control group in terms of static balance because of core muscle strengthening workouts. The results obtained confirm the effectiveness of core muscle strengthening workouts in improving the static balance of judo players. Therefore, coaches can use these workouts during the preparation period and can manage training loads according to the characteristics of the players by regularly measuring the static balance through field or laboratory, results of this tests can be help in planning training programs.
Effects of Different Concurrent Training Methods on Aerobic and Anaerobic Capacity in U 21 soccer players
Authors: Youcef Khoudja , Mokhtar Mime , Adel Belkadi , Wahib Beboucha
Published: September 2022

Purpose: The main aim of this study is to investigate the effect of the concurrent training method of muscular strength training or muscular endurance training combined with high-intensity interval training (HIIT) on the aerobic threshold (AerT) and anaerobic threshold (AT). Material and methods: Twenty soccer player from the University team were recruited. Participants were divided into muscular strength training group (MS, N = 10) and the muscular endurance training group (ME, N = 10). All subjects sustained the regular specific training programs during the experimental period and had additional different concurrent training twice per week for twelve weeks. power output during the graded exercise test, peak power (PP), average power (AP), fatigue index (FI) during anaerobic power test were tested by graded exercise test on Wingate anaerobic power test. as well as one-repetition maximum (1-RM) of lower limbs and Romanian Deadlift (RDL) - Hamstring Leg Exercise were tested simultaneously before and after the experiment. Data were analysed by two-way mixed design ANOVA. Results: After 12 weeks of training, the AT power output, 1-RM of half squat and the 1-RM of RDL were significantly higher than before training (MS: 407.12 ± 52.92 vs 431.78± 48.84 watt, 157.45 ± 35.66 vs 169.87 ± 47.31 kg, 120.16± 15.28 vs 122.56± 19.39 kg; ME: 411.11 ± 48.48 vs 429.16 ± 52.13 watt, 135.34 ± 26.27 vs 144.41 ± 35.78 kg, 96.93 ± 24.57 vs 103.46 ± 24.15 kg, p .05) in MS group and ME group. Time to exhaustion of graded exercise test in ME group was significantly higher than before training (22.13 ± 7.73 vs 25.78 ± 8.74 min, 23.44 ± 7.73 vs 24.78 ± 8.74 p .05). The AerT power output, PP, AP, and FI were no significant changes in both groups. Nevertheless, all dependent variables were no significant difference between groups before and after training. Conclusion: Conducting the concurrent training method of muscular strength training or muscular endurance training combined with HIIT twice per week for twelve weeks increased soccer players’ aerobic endurance as well as 1-RM of lower limbs. The concurrent training method of muscular endurance training combined with HIIT also promoted the performance of time to exhaustion. However, there were no significant difference between two training methods and minor significant benefits on anaerobic power.
The Effectiveness of a Suggested Mentoring Program Using Cascading Relaxation and Recreational Sporting Activity to Reduce the Level of Aggressive Behavior Among Secondary School Students Ages 16 to 18 Years An Experimental Study on Male Students of Sidi Saada Secondary School, Relizane, Algeria
Authors: Ahmed Gorine , Mokrani Djamel , Benklaouaz Touati Ahmed
Published: September 2022

This study aims to find out the effectiveness of a psychological counseling program using sequential relaxation and recreational sports activity on reducing the level of aggressive behavior as a feature of both physical and verbal types among secondary school students. The study contained two homogeneous and equal groups, one experimental and one controlled, and the researchers applied the proposed program to the experimental sample of (35) students (males) first year secondary level while the control group underwent the regular program, the researchers used the experimental approach because it was appropriate for the nature of the study and its objectives. The duration of the program was limited to (08) weeks and 01 educational units per week, the duration of each unit (75 minutes) and included the units of the proposed program on (cascading relaxation exercises - recreational sports activities). The results of this study showed statistically significant differences in the post measurement between the members of the experimental sample and the control sample in the post measurement, where the level of aggressive behavior decreased in both physical and verbal types for the members of the experimental sample. Based on the results, it can be concluded that the increase in cholesterol triglycerides and some parameters of body structure affected the level of health status as well as body composition in students.
Dalcroze Method and Its Impact to Motor, Locomotor Status and Movement Aestethic
Authors: Lazić Svetlana
Published: September 2022

Dalcroze method presents the process of linking the sound into the body action in which musical skills can overcome through kinaesthetic exercises. The emphasis is on attention focused and directed to movement realisation, which is why the conscious attention between body and mind arise. The natural body movement, supported by musical content is mastering into organised act, by which body becomes an instrument and transfer certain parts of music in the movement. The author offers the review of researches about Dalcroze method contribution to every age of life, concluding that it presents a good strategy for every day’s life monitoring, the way of integrative learning and melodic fulfilment of physical exercises. It doesn’t know the age restrictions and is applicable through the whole life.
For an epistemology of transition: Paul B. Preciado, psychoanalysis and the regime of sexual difference
Authors: Franco Alessia
Published: September 2022

This paper aims to illustrate Paul B. Preciado’s thought on the epistemology of transition, which should take over from the current epistemological regime of sexual difference based on heterobinarism. Starting in particular from the lecture given by Preciado in Paris in 2019, we intend to focus on the main axes of Preciado’s thought on the topic: first and foremost, the necessity of the denaturalization of gender with respect to biological sex; the denunciation of the normalization and medicalization endured by trans or intersex bodies, “deviants” with respect to heterobinarism; the ethnocentrism and necropolitical power of medical and disciplinary institutions vis-à-vis “deviants” and “monstrous”; and the concept of “transition” elaborated by Preciado as a decolonization with respect to the epistemology and disciplinary institutions of the current regime of sexual difference.
Predictors of tuberculosis disease in smokers: a case-control study in northeastern Malaysia
Authors: Tengku Khalid Tengku Noor Farhana , Wan Mohammad Wan Mohd Zahiruddin , Ab Samat Razan , Nik Husain Nik Rosmawati
Published: September 2022

Objective

Tuberculosis (TB) is a leading infectious disease. However, many TB cases remain undetected and only present symptoms at a late stage of the infection. Therefore, targeted TB screening in high-risk populations, including smokers, is crucial. This study aimed to determine the predictors of TB disease among the smoker population in northeast Malaysia from 2019 to 2020.

Methods

A case-control study was conducted involving smokers aged 18 years and older from health clinics in Bachok Kelantan, Malaysia. Data were collected via face-to-face interviews or telephone calls from 159 participants, randomly selected from outpatient TB records. Simple and multiple logistic regression, using R software, were used to identify the determinants of TB.

Results

Most participants were male (59.1%) and had a secondary education (56.0%). Active smokers constituted 35.2% of the group, and the mean (SD) duration of exposure to smoking was 23.9 (16.47) and 18.4 (12.84) years for the case and control groups, respectively. Being an ex-smoker (adjusted odds ratio (AOR) 6.17; 95% CI [1.55–28.32]; p = 0.013), weight loss (AOR 13.45; 95% CI [4.58–44.46]; p < 0.005), night sweats (AOR 63.84; 95% CI [8.99–1392.75]; p < 0.005) and duration of symptoms (AOR 1.02; 95% CI [1.01–1.04]; p = 0.022) were shown to be significant predictors for TB disease.

Conclusion

Four predictors of TB disease in the population of smokers were recognised in this study and should be prioritised for early TB screening and diagnosis. This may help increase TB detection, initiate prompt treatment and reduce complications among the group at risk for TB.
Preprocessing Method of 3D Topographic Modeling for Wildland Fire Simulation
Authors: Kim Sung-Chan
Published: September 2022

This study was conducted to develop a preprocessing method that generates a computational geometry for a wildland fire simulation based on topographic data. The computational domain comprised an area of 2 km × 2 km with a height of 1.2 km, including the terrain geometry and atmosphere, in Palgongsan Natural Park near the Gatbawi district. BLENDER 2.92, an open-source 3D computer graphics software tool, was used to create the terrain surface and 3D solid objects based on the data of a digital elevation model, considering the spatial resolution of 90 m provided by the SRTM of the NASA. The level-set method of the FDS model was used to track the wildland fire spread, assuming that the speed of the wind from the east was 10 m/s. The calculated result of the fire spread was dependent on the grid size of the computational mesh and the voxel size of the 3D solid objects.
Double Gasket Research and Development to Improve the Fire Resistance Performance of a No Threshold Fire Door
Authors: Won Sung-Ho , Lee Joo-won , Lee Hae-Yeol
Published: September 2022

Fire doors are installed to prevent the spread of fire in a building, whereby gaps between the door frame and door leaf are blocked using gaskets of various materials and shapes. However, there are many difficulties in ensuring the desired performance. This study focuses on the research and development of a double gasket that can improve the fire resistance performance of a no threshold fire door, in which the door frame under the fire door has been removed. This is a product that has been researched and developed to improve fire resistance and airtightness in no threshold fire doors by connecting it to the gasket to ensure there is no breakage.
Tailor-made Pulmonary Rehabilitation Program Aiding Return to Preinfection Fitness in Massive Cavitatory Lung Abscess: A Case Report
Authors: Kaple Gayatri Surendra , Yadav Vaishnavi , Jain Moli , Bhakney Pallavi , Vardhan Vishnu
Published: September 2022

Lung abscess is a form of liquefactive necrosis of the lung tissue that causes the formation of cavities (greater than 2 cm) which are filled with necrotic debris and fluid because of microbial infection. Aspiration, which may happen while the patient is not conscious and end in a pus-filled cavity. It is very rare to find out lung abscess with a complicated infection of Streptococcus pneumoniae stereotype 6B. A 42-year-old male patient was referred to a tertiary care hospital with chief complaints of breathlessness of grade II on the Modified Borg Scale, cough with expectoration, and right-sided chest pain. Chest X-ray and High Resolution Computed Tomography (HRCT) High Resolution Computed Tomography (HRCT) scan of the thorax were done and the patient was diagnosed with right lower lobe lung abscess caused by Streptococcus pneumoniae. The patient was managed by bronchoscopy and bronchoalveolar lavage (washing). A complete plan of rehabilitation was designed to meet the patient's objectives, and it was executed and followed for 1 month. The patient showed considerable functional improvement in terms of aerobic capacity, endurance, and exercise tolerance ability. It was concluded that medical care combined with pulmonary rehabilitation, together as a multidisciplinary approach result in improved outcomes related to the quality of life of the patients.
Assessment of Reliability of Advanced Lipid Parameters for Premature Coronary Artery Disease in Young Indians: A Case-control Study
Authors: Patil Rahul , Kudineerakatte Sheetal , Vijan Vikrant , Edwin Dimpu
Published: September 2022

Introduction: Coronary Artery Disease (CAD) appears even in patients with normal level of conventional lipid parameters. But due to lack of specific guidelines on Indian population, involving detection of advanced lipid indices, has resulted in inadequate finding, management, and control of cardiovascular disease risks. This emphasises the need of advanced lipid indices for prediction of CAD at younger age. Aim: To evaluate the reliability of advanced lipid indices compared to conventional lipid parameters for diagnosis of CAD. Also, to determine the effectiveness of advanced lipid indices in screening young Indian for the risk of Premature CAD (PCAD). Materials and Methods: A case-control study was conducted at a tertiary care centre in Bengaluru, Karnataka, India, between January 2020 to January 2022. The study enrolled total 983 subjects which were divided into cases and controls. The estimation of usual lipid profile (Triglycerides (TG), High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL), and Total Cholesterol (TC)) and advanced lipid parameters, oxidized LDL, Apolipoprotein A1 (Apo A1), lipoprotein (a), small density LDL (Sd-LDL), and Apolipoprotein B-100 (Apo B) was studied for each enrolled individual. These lipid parameters were used to calculate various lipid indices like Lipid Pentad Index (LPI), Lipid Tetrad Index (LTI), Atherosclerotic Index (AI), and Advanced Atherosclerotic Index (AAI); and TC/HDL ratio. Statistical analysis was performed using Chi-square test, Fisher’s exact test, multivariate logistic regression, and Student’s t-test/ Analysis of Variance (ANOVA) test. Results: Mean age of patient in case group was 32.31±5.42 years and individuals in control group was 32.13±5.21 years. Among case group, 427 (88.04%) enrolled males had PCAD. In case group, total 45 (9.28%) had diabetes, 51 (10.51%) had family history of PCAD and 230 (47.42%) patients were smokers. The values of TC (p=0.009), LDL (p<0.001), Apo A1 (p<0.001), HDL (p<0.001) were significantly lower among cases compared to controls, lipoprotein (a) (p=0.04), Sd-LDL (p<0.001), TG (p<0.001) were significantly higher among cases compared to controls. Among the calculated lipid indices, the values of AI (p<0.001), LTI (p<0.001), LPI (p=0.001) and AAI (p=0.01) were significantly higher among cases as compared to controls. Conclusion: Advanced lipid indices are statistically more reliable than conventional lipid parameters. Newer advanced lipid indices are effective in screening young Indian individuals for the risk of PCAD.
Constraints Faced by the Extension Personnel in Exerting their Professional Competence
Authors: Nair Neethu B. , Jahagirdar K. A.
Published: September 2022

A study was conducted in three districts of Karnataka including, Dharwad, Vijayapura and Bagalkot on constraints faced by the extension personnel working in KVK and Development Departments. Data were collected through questionnaire and statistical methods such as percentage, frequency and ranking were used for analyzing the data. Constraints were classified as institutional and personnel, A total of twelve institutional and seven personnel constraints were reported by the extension personnel. Among the institutional constraints, majority (94.73%) of the extension personnel reported the constraints of ‘bureaucratic delays and focus on paperwork’, ‘Inadequate staff’ (77.19%), ‘less opportunities for promotion’ (70.52%) as the major constraints. While the major personnel constraints faced by the extension personnel were ‘Lack of accurate and effective feedbacks due to time lag of functionaries’ (92.98%), ‘Lack of coordination among the staff’ (81.75%) and Lack of advanced training (70.52%).
Effect of Nitrogen and Sulphur on Yield and Economics of Wheat (Triticum aestivum L.)
Authors: Ghanasai Koppu , Singh Rajesh , Bhanuteja Gurujala , Ashritha Addepalli
Published: September 2022

A field experiment was conducted during Rabi 2021-20222 at Crop Research Farm, Department of Agronomy, SHUATS, Prayagraj (U.P). The soil of experimental plot was sandy loam in texture, nearly neutral in soil reaction (pH 7.1), low in organic carbon (0.36 %), available N (171.48 kg/ha), available P (15.2 kg/ha) and available K (232.5 kg/ha). The experiment was laid out on Randomized Block Design with nine treatments each replicated thrice on the basis of one year experimentation. Variety of wheat DBW-187, Furrow Irrigated Raised Bed technique for irrigation. The treatments which are T1: Nitrogen 80 kg/ha,+ Sulphur 15 kg/ha, T2: Nitrogen 80 kg/ha + Sulphur 30 kg/ha, T3: Nitrogen 80 kg/ha + Sulphur 45 kg/ha, T4: Nitrogen 100 kg/ha + Sulphur 15 kg/ha, T5: Nitrogen 100 kg/ha + Sulphur 30 kg/ha, T6: Nitrogen 100 kg/ha + Sulphur 45 kg/ha, T7: Nitrogen 120 kg/ha + Sulphur 15 kg/ha, T8: Nitrogen 120 kg/ha + Sulphur 30 kg/ha, T9: Nitrogen 120 kg/ha + Sulphur 45 kg/ha are used. The results showed that application of Nitrogen 120 kg/ha + Sulphur 45 kg/ha was recorded significantly maximum No. of Grains/spike (47.34), Test weight (38.30 g), Grain yield (6.14 t/ha), Straw yield (9.52 t/ha), gross returns (Rs.99911.66/ha), net return (Rs.67591.73/ha) and benefit cost ratio (2.09) was obtained as compared to other treatments.
Morpho-physiological Responses of Sorghum Cultivars to Drought Stress
Authors: Jeevitha R. , Vijayalakshmi D. , Vinitha A. , Gowsiga S. , Ramya G.
Published: September 2022

The experiment was carried out to assess the following objectives: (i) To understand the effect of drought stress on plant height and leaf area in diverse sorghum genotypes. (ii) To study the alterations in chlorophyll index and yield components under drought stress. (iii) To correlate yield with all morpho-physiological traits to understand drought tolerance mechanism of sorghum. Screening experiment was carried out in Augmented design I during April 2022 to July 2022 at Rain Out Shelter (ROS), Department of Crop Physiology, Tamil Nadu Agricultural University, Coimbatore. 33 germplasms from Agricultural Research Station, Kovilpatti (ARS, Kovilpatti) and Indian Council of Agricultural Research- Indian Institute of Millet Research, Hyderabad (ICAR-IIMR, Hyderabad) were collected. Among 33, M35-1, K -12, CSV 27 and CSV 29-R were used as checks, where all the germplasms were cultivated with two treatments under field conditions; T1: (Control) well watered throughout life cycle, T2: Two weeks of drought stress (50%) at booting stage. Traits such as plant height and leaf area, were recorded before and after imposing drought. Chlorophyll index, ear head weight, ear head length, grain yield, total dry matter production, harvest index were recorded after imposing drought stress in control and drought stress. Under drought stress morpho-physiological and yield traits significantly reduced compared to control. There was a significant positive correlation of yield under stress with all the morpho-physiological traits. Among ICAR-IIMR sorghum germplasm collections screened for drought stress tolerance PEC 14, PEC 17, PEC31, PEC 34 EP 90 showed drought tolerance on par with the checks. Similarly, TKSV 1036, TKSV 1707, TKSV 1801, TKSV 1802 germplasms from ARS, Kovilpatti were tolerant to drought stress at booting stage.
Qualitative Analysis and Statistical Evaluation of Curcumin Content and Total Phenolic Compounds in Distinct Turmeric (Curcuma longa L.) Germplasms
Authors: Shankar Bandi Arpitha , Arora Vaishali , Yadav M. K. , Kumar Mukesh , Singh Bijendra , Burman Vishakha
Published: September 2022

Aim: Nowadays, turmeric value has increased with the presence of curcumin content and total phenols, as they are highly advantageous and useful in different areas of study. Salinity stress is also a major problem in certain areas under which many turmeric germplasms show reduced phenolic compounds and curcumin content. Therefore, the present study is aimed at identifying the different varieties that are diverse with high yields and maximum production so that the salt stress effects can be studied.

Methodology: This study was carried out using Factorial Completely Randomized Design (FCRD). Statistical analysis was done by applying the Duncan Multiple Range Test (DMRT) in relation to the concentrations of total phenolic compounds and curcumin content.

Results: We observed, a gradual rise in the total phenol content and curcumin content in all the germplasms. In particular, treatments including maximum salinity stress like 100 mM concentration gave better results compared to the control and 50 mM concentration (Figs. 2 & 3). These observations can be considered as stress-responsive mechanisms developed by the turmeric plants under salt stress conditions. Compared to all the selected germplasms, Vallabh Sharad and Selection 1 gave maximum output for total phenol content. 2.12 (leaf) and 0.28 (rhizome) values, which are maximum compared to controls observed in the case of 100 mM concentration. Also, Selection 1 gave 0.58 (rhizome) curcumin content, which is the maximum compared to the control.

Conclusions: Therefore, this increase in the phytochemicals in plants, helps in the increase of the medicinal properties in the turmeric plants also, internally protecting them from salt stress.
Evaluation of Genetic Variability, Heritability and Genetic Advance in Garden Pea (Pisum sativum L.)
Authors: Saivamsireddy Gurrala , Parveen Shama
Published: September 2022

Ten pea genotypes had their heritability evaluated in 2021 and '22. Except for the proliferation of plants, change analysis has a substantial impact on all other factors. Unit yield per plant (15.3,16.97) had the highest genotypic and phenotypic co-effective of variety, followed by seed yield per plot (13.91,18.00), and very long time to first bloom (3.56, 3.63) had the lowest; high heritability with hereditary development according to penny of mean was recorded for yield per plant (81.00, 28.4) and case yield per plant (59.00, 22.10), and very long time to first bloom (3.63) had the lowest (0.6, 1.72). According to the results of this research, highlighting these features may significantly boost production.
Analytic Representation of Probability Density Function of Random Variable in Distributional Sense
Authors: Bedjeti Bedrije , Saliji Mejdin , Eraković Vesna Manova
Published: September 2022

In this paper, we have proved that the probability density function \(f(t)\) considered as a distribution has a Cauchy representation in \(O_\alpha^{\prime}\). The distribution space \(O_\alpha^{\prime}\) is intermediate space between \(E^{\prime}\) and \(D^{\prime}\).
O BRASIL PODE MAIS: CAMINHOS PARA O DESENVOLVIMENTO SUSTENTÁVEL
Authors: Gimene Márcio , Cardoso Jr José Celso
Published: September 2022

Este texto é uma versão resumida do documento de mesmo nome sob responsabilidade da ARCA – Articulação de Carreiras Públicas para o Desenvolvimento Sustentável. Em sua versão ampliada, o documento percorre 14 (quatorze) áreas programáticas de atuação governamental, a saber: 1) Inserção internacional soberana; 2) Desenvolvimento, ciência, tecnologia e inovação;3) Macroeconomia e regras fiscais; 4) Reforma tributária justa e solidária; 5) Seguridade Social: Saúde, Assistência e Previdência Social; 6) Desemprego zero e trabalho digno para todos; 7) Educação e formação cidadã; 8) Cultura, diálogo social e construção da alteridade; 9) Desigualdades de gênero, raça e etnia; 10) Ordenamento territorial e desenvolvimento regional; 11)  Sustentabilidade socioambiental; 12) Infraestrutura econômica e social; 13) Segurança pública; 14) Reformaadministrativa e fortalecimento do Estado, das instituições e da democracia.Para todas elas, foi feito um esforço coletivo de se produzir um macrodiagnóstico crítico ao estado situacional de cada área, ao mesmo tempo que um esforço propositivo com o intuito de gerar insumos para a construção de alternativas críveis e coerentes ao desenvolvimento brasileiro a futuro, uma vez passada a avalanche neoliberal-autoritária ainda em curso – mas em estágiode superação positiva – no país. Nesta versão aqui resumida, optou-se por apresentar apenas os capítulos correspondentes aos temas ligados à soberania nacional, macroeconomia, reforma tributária, trabalho, emprego e renda, sustentabilidade socioambiental e fortalecimento do Estado, das instituições e da democracia.

Com esta iniciativa, esperamos ter cumprido nosso papel como cidadãos e servidores públicos engajados na descoberta de alternativas civilizatórias para a reconstrução do Brasil. Afinal, o Brasil pode mais!
ADMINISTRAÇÃO POLÍTICA DA TECNOLOGIA E DO TRABALHO PARA A PROMOÇÃO DA VIDA
Authors: Santos Antonio Miguel Barros Tenório Varjão dos
Published: September 2022

Em 1930, o economista britânico John Maynard Keynes escreveu sobre o futuro dos netos das pessoas de sua geração, imaginando que, por força do progresso tecnológico, eles seriam emancipados do trabalho, teriam suas necessidades materiais satisfeitas e poderiam se dedicar a causas mais elevadas. Passados mais de 90 anos desde a publicação do texto de Keynes, embora a tecnologia tenha superado em muito a imaginação do autor, o futuro profetizado por ele ainda não chegou. Este ensaio analisa os motivos de o progresso social profetizado por Keynes não ter se concretizado, diagnosticando a maneira como historicamente a tecnologia tem impactado na vida das pessoas e questionando a existência ou a necessidade de construção de um desenho social, mais justo e fraterno, que compatibilize a tecnologia com a ciência e a vida, e que deva ser perseguido mediante a elaboração e a execução de um projeto nacional.
Surface Bandgap Engineering of Nanostructured Implants for Rapid Photothermal Ion Therapy of Bone Defects
Authors: Xue Yang , Zhang Lan , Liu Fuwei , Zhao Yiwei , Zhou Jianhong , Hou Yan , Bao Han , Kong Liang , Ma Fei , Han Yong
Published: September 2022

Bone defects are seriously threatening the health of orthopedics patients and it is difficult for implants to accelerate bone regeneration without using bone growth factors. Herein, a fast photothermal ion therapeutic strategy is developed based on the bandgap engineering of nanostructured TiO2 through (Si/P)‐dual elemental doping by micro‐arc oxidation treatment of titanium implants. The (Si/P)‐dual doping can tune the surface bandgap structure of TiO2 by decreasing bandgap and broadening valence band simultaneously, which is confirmed by density functional theory calculations. It not only endows the implants with a mildly photothermal effect under near‐infrared (NIR) light irradiation, but also creates an (Si/P) ion‐rich microenvironment around the implants. This photothermal ion microenvironment can tune the behaviors of osteoblasts by promoting p38/Smad and ERK signaling pathways of osteoblasts, thus significantly upregulating the expression of osteogenesis genes by the synergistic action of mild photothermal stimulation and increased release of Si/P ions. The in vivo results are also in good agreement with in vitro tests, i.e., under NIR light irradiation, the photothermally responsive TiO2 enhances the bone formation and osteointegration with implants. Therefore, this kind of photothermal ion strategy is a promising remote and noninvasive therapeutic mode for promoting bone regeneration of Ti implants.
Hydro/Organo/Ionogels: “Controllable” Electromagnetic Wave Absorbers
Authors: Zhao Zehao , Zhang Limin , Wu Hongjing
Published: September 2022

Demand for electromagnetic wave (EMW) absorbers continues to increase with technological advances in wearable electronics and military applications. In this study, a new strategy to overcome the drawbacks of current absorbers by employing the co‐contribution of functional polymer frameworks and liquids with strong EMW absorption properties is proposed. Strongly polar water, dimethyl sulfoxide/water mixtures, and highly conductive 1‐ethyl‐3‐methylimidazolium ethyl sulfate ([EMI][ES]) are immobilized in dielectrically inert polymer networks to form different classes of gels (hydrogels, organogels, and ionogels). These gels demonstrate a high correlation between their dielectric properties and polarity/ionic conductivity/non‐covalent interaction of immobilized liquids. Thus, the EMW absorption performances of the gels can be precisely tuned over a wide range due to the diversity and stability of the liquids. The prepared hydrogels show good shielding performance (shielding efficiency > 20 dB) due to the high dielectric constants, while organogels with moderate attenuation ability and impedance matching achieve full‐wave absorption in X‐band (8.2–12.4 GHz) at 2.5 ± 0.5 mm. The ionogels also offer a wide effective absorption bandwidth (10.79–16.38 GHz at 2.2 mm) via prominent ionic conduction loss. In short, this work provides a conceptually novel platform to develop high‐efficient, customizable, and low‐cost functional absorbers.
50C Fast‐Charge Li‐Ion Batteries using a Graphite Anode
Authors: Sun Chuangchao , Ji Xiao , Weng Suting , Li Ruhong , Huang Xiaoteng , Zhu Chunnan , Xiao Xuezhang , Deng Tao , Fan Liwu , Chen Lixin , Wang Xuefeng , Wang Chunsheng , Fan Xiulin
Published: September 2022

Li‐ion batteries have made inroads into the electric vehicle market with high energy densities, yet they still suffer from slow kinetics limited by the graphite anode. Here, electrolytes enabling extreme fast charging (XFC) of a microsized graphite anode without Li plating are designed. Comprehensive characterization and simulations on the diffusion of Li+ in the bulk electrolyte, charge‐transfer process, and the solid electrolyte interphase (SEI) demonstrate that high ionic conductivity, low desolvation energy of Li+, and protective SEI are essential for XFC. Based on the criterion, two fast‐charging electrolytes are designed: low‐voltage 1.8 m LiFSI in 1,3‐dioxolane (for LiFePO4||graphite cells) and high‐voltage 1.0 m LiPF6 in a mixture of 4‐fluoroethylene carbonate and acetonitrile (7:3 by vol) (for LiNi0.8Co0.1Mn0.1O2||graphite cells). The former electrolyte enables the graphite electrode to achieve 180 mAh g−1 at 50C (1C = 370 mAh g−1), which is 10 times higher than that of a conventional electrolyte. The latter electrolyte enables LiNi0.8Co0.1Mn0.1O2||graphite cells (2 mAh cm−2, N/P ratio = 1) to provide a record‐breaking reversible capacity of 170 mAh g−1 at 4C charge and 0.3C discharge. This work unveils the key mechanisms for XFC and provides instructive electrolyte design principles for practical fast‐charging LIBs with graphite anodes.
A Molecular‐Sieve Electrolyte Membrane enables Separator‐Free Zinc Batteries with Ultralong Cycle Life
Authors: Zhu Junbo , Bie Zhe , Cai Xinxin , Jiao Zhaoyang , Wang Ziting , Tao Jingchen , Song Weixing , Fan Hong Jin
Published: September 2022

The poor stability of the zinc‐metal anode is a main bottleneck for practical application of aqueous zinc‐ion batteries. Herein, a series of molecular sieves with various channel sizes are investigated as an electrolyte host to regulate the ionic environment of Zn2+ on the surface of the zinc anode and to realize separator‐free batteries. Based on the ZSM‐5 molecular sieve, a solid–liquid mixed electrolyte membrane is constructed to uniformize the transport of zinc ions and foster dendrite‐free Zn deposition. Side reactions can also be suppressed through tailoring the solvation sheath and restraining the activity of water molecules in electrolyte. A V2O5||ZSM‐5||Zn full cell shows significantly enhanced performance compared to cells using glass fiber separator. Specifically, it exhibits a high specific capacity of 300 mAh g−1, and a capacity retention of 98.67% after 1000 cycles and 82.67% after 3000 cycles at 1 A g−1. It is attested that zeolites (ZSM‐5, H‐β, and Bate) with channel sizes of 5–7 Å result in best cycle stability. Given the low cost and recyclability of the ZSM and its potent function, this work may further lower the cost and boost the industrial application of AZIBs.
Fe‐Catalyzed Three‐Component Reaction for the Synthesis of 2,3′‐Biquinolines
Authors: Xiao Fuhong , Yang Gang , Yao Lin , Mao Guojiang , Deng Guo‐Jun
Published: September 2022

Fe‐catalyzed three‐component strategy have been developed for the synthesis of 2,3′‐biquinolines from readily available 2‐methyl quinolines, anthranils andN,N‐dimethylacetamide (DMA), This annulation procedure undergoes C(sp3)−H activation, amination, nucleophilic addition, dehydration and oxydehydrogenation steps. DMA acts not only as a solvent but also as a one carbon donor in the reaction.

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Exploring Physics of Ferroelectric Domain Walls in Real Time: Deep Learning Enabled Scanning Probe Microscopy
Authors: Liu Yongtao , Kelley Kyle P. , Funakubo Hiroshi , Kalinin Sergei V. , Ziatdinov Maxim
Published: September 2022

The functionality of ferroelastic domain walls in ferroelectric materials is explored in real‐time via the in situ implementation of computer vision algorithms in scanning probe microscopy (SPM) experiment. The robust deep convolutional neural network (DCNN) is implemented based on a deep residual learning framework (Res) and holistically nested edge detection (Hed), and ensembled to minimize the out‐of‐distribution drift effects. The DCNN is implemented for real‐time operations on SPM, converting the data stream into the semantically segmented image of domain walls and the corresponding uncertainty. Further the pre‐defined experimental workflows perform piezoresponse spectroscopy measurement on thus discovered domain walls, and alternating high‐ and low‐polarization dynamic (out‐of‐plane) ferroelastic domain walls in a PbTiO3 (PTO) thin film and high polarization dynamic (out‐of‐plane) at short ferroelastic walls (compared with long ferroelastic walls) in a lead zirconate titanate (PZT) thin film is reported. This work establishes the framework for real‐time DCNN analysis of data streams in scanning probe and other microscopies and highlights the role of out‐of‐distribution effects and strategies to ameliorate them in real time analytics.
Self‐Sustaining Fluorination of Active Methylene Compounds and High‐Yielding Fluorination of Highly Basic Aryl and Alkenyl Lithium Species with a Sterically Hindered N‐Fluorosulfonamide Reagent
Authors: Yang Yuhao , Hammond Gerald B. , Umemoto Teruo
Published: September 2022

Fluorination of carbanions is pivotal for the synthesis of fluorinated compounds, but the current N‐F fluorinating agents have significant drawbacks due to many reactive locations that surround the reactive N−F site. By developing a sterically hindered N‐fluorosulfonamide reagent, namely N‐fluoro‐N‐(tert‐butyl)‐tert‐butanesulfonamide (NFBB), we discovered a conceptually novel base‐catalyzed, self‐sustaining fluorination of active methylene compounds and achieved the high‐yielding fluorination of the hitherto difficult highly basic (hetero)aryl and alkenyl lithium species. In the former, the mild and high yield fluorination of active methylene compounds exhibited wide functional group tolerance and its novel catalytic fluorination‐deprotonation cycle mechanism was demonstrated by deuterium‐tracing experiments. In the latter, NFBB reacted with a variety of highly basic (hetero)aryl and alkenyl lithium species to provide the desired fluoro (hetero)arenes and alkenes in unprecedented high or quantitative yields.
Genome‐wide and expression‐profiling analyses of the cytochrome P450 genes in Tenebrionidea
Authors: Wang Yu‐Qin , Li Guang‐Ya , Li Lu , Song Qi‐Sheng , Stanley David , Wei Shu‐Jun , Zhu Jia‐Ying
Published: September 2022

Cytochrome P450 monooxygenases (CYPs) are present in almost all areas of the tree of life. As one of the largest and most diverse superfamilies of multifunctional enzymes, they play important roles in the metabolism of xenobiotics and biosynthesis of endogenous compounds, shaping the success of insects. In this study, the CYPome (an omics term for all the CYP genes in a genome) diversification was examined in the four Tenebrionidea species through genome‐wide analysis. A total of 483 CYP genes were identified, of which 103, 157, 122, and 101 were respectively deciphered from the genomes ofTebebrio molitor,Asbolus verucosus,Hycleus cichoriiandHycleus phaleratus. These CYPs were classified into four major clans (mitochondrial, CYP2, CYP3, and CYP4), and clans CYP3 and CYP4 are most diverse. Phylogenetic analysis showed that most CYPs of these Tenebrionidea beetles from each clan had a very close 1:1 orthology to each other, suggesting that they originate closely and have evolutionally conserved function. Expression analysis at different developmental stages and in various tissues showed the life stage‐, gut‐, salivary gland‐, fat body‐, Malpighian tubule‐, antennae‐, ovary‐ and testis‐specific expression patterns ofT. molitorCYP genes, implying their various potential roles in development, detoxification, immune response, digestion, olfaction, and reproduction. Our studies provide a platform to understand the evolution of Tenebrionidea CYP gene superfamily, and a basis for further functional investigation of theT. molitorCYPs involved in various biological processes.
Efficacy and Safety of Botulinum Toxin in Adults with Raynaud's Phenomenon Secondary to Systemic Sclerosis: A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Study
Authors: Senet Patricia , Maillard Hervé , Diot Elisabeth , Lazareth Isabelle , Blaise Sophie , Arnault Jean‐Philippe , Pistorius Marc‐Antoine , Boulon Carine , Cogrel Olivier , Warzocha Ursula , Rivière Sébastien , Malloizel‐Delaunay Julie , Servettaz Amélie , Sassolas Bruno , Viguier Manuelle , Monfort Jean‐Benoit , Janique Solène , Vicaut Eric ,   the BRASS collaborators
Published: September 2022

Objective

To determine whether a single session of botulinum toxin type A (BTA) injections into both hands more effectively decreases the frequency of systemic sclerosis–associated Raynaud's phenomenon (SSc‐RP) episodes than placebo.

Methods

This multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group phase III trial in patients with SSc‐RP assessed the effect of 50‐unit BTA or placebo injections into the palms of both hands around each neurovascular bundle during 1 session in winter. The primary end point was the between‐group difference in the median change in the number of RP episodes from baseline (day 0) to 4 weeks postinjection. Values between the groups were compared with the Wilcoxon rank‐sum test.

Results

The intent‐to‐treat analysis included 46 BTA‐treated patients and 44 placebo recipients. At 4 weeks after assigned treatment injections, the median number of daily RP episodes decreased comparably in the BTA and placebo groups (median change –1 episode/day [interquartile range (IQR) –1.5, 0 episodes/day] and –1 episode/day [IQR –2.5, 0 episodes/day], respectively) (P = 0.77 versus placebo). Moreover, change in Raynaud's Condition Score, quality of life assessed by Health Assessment Questionnaire disability index, and hand function assessed by shortened Disabilities of the Arm, Shoulder, and Hand (QuickDASH) and Cochin Hand Function Scale from baseline to follow‐up weeks 4, 12, and 24 did not differ significantly between groups. The BTA group experienced transient hand muscle weakness significantly more frequently (P = 0.003).

Conclusion

Neither the primary nor secondary end points were reached, and our results do not support any beneficial effect of palmar BTA injections to treat SSc‐RP.

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