bluuebunny/crossref_metadata_2025 huggingface dataset:
I.P. Filevich and Carpathian Rus Part 1. Biography
Authors:   Saint Petersburg State University (Saint Petersburg, Russian Federation), Sulyak S.G.
Published: January 2021

Ivan Porfirevich Filevich (August 20 (September 1), 1856 – January 7 (20), 1913) – a Russian historian, publicist, and public figure, born in Chełm Land to the family of a Uniate priest, a native of Galicia, Orthodox. He graduated from St. Petersburg University, later taught Russian language, literature, and history at the First Realschule and at the Gymnasium of the Imperial Philanthropic Society in St. Petersburg. Since 1890, he worked at the Department of Russian History at the Imperial Warsaw University, first as an extra-ordinary professor, and since 1897 as an ordinary professor. His origin predetermined his interest in the history of Carpathian Rus, in particular Galicia and Chełm Land, and its population. In 1890, he received a Master’s degree for his work “The Struggle of Poland and Lithuania-Rus for the Galician-Vladimir Legacy”. In 1897, he defended his doctoral degree at Kazan University on “History of Ancient Rus. Territory and Population”. He frequently travelled across Carpathian Rus. Having retired in 1908, he devoted himself to journalistic and social activities. Ivan Filevich authored monographs: “The Struggle of Poland and Lithuania-Rus for the Galicia-Vladimir Legacy. Historical Sketches” (1890) and “History of Ancient Rus. Territory and Population” (1896), as well as numerous studies, among which were: “A Forgotten Corner” (1881), “Ugric Rus and Related Issues and Tasks of Russian Historical Science” (1894), “Sketch of the Carpathian Territory and Population” (1895), “On the development of geographical nomenclature” (1899), “Concerning the theory of two Russian nationalities” (1902), “The question of two Russian nationalities and ‘Kievan Antiquity’” (1902), “Carpathian Rus on the eve of the 20th century” (1905), “From the History of Carpathian Rus. Essays on Galician-Russian Life Since 1772 (1848–1866)” (1907) etc. Many of his minor materials (criticism and bibliographies) were published in Izvestia of the St. Petersburg Slavic Charitable Society, Slavic Review, Journal of the Ministry of Public Education, Warsaw University News, etc. In his last years, Filevich was actively involved in social and journalistic activities, popularizing scientific knowledge and informing readers about Western Russian, especially Chełm and Polish issues. His articles were published mainly in Novoye Vremya. He drew up notes and historical references for the development of legislative proposals on the Chełm and presented historical, statistical, and economic materials in the Duma commission on the separation of Chełm. Filevich managed to see the results of his work. The law “On the formation of Chełm province from the eastern parts of the Lublin and Sedletsk provinces, with its removal from the administration of the Warsaw Governor-General” was approved on June 23 (July 6) 1912. However, in fact, the province was officially opened on September 8, 1913, after I.P. Filevich’s death.
Graphic Novels in the Repertoire of Modern Russian Publishers
Authors:   Ballet magazine (Moscow, Russian Federation), Panferova Olga Yu. , Mzhelskaya Elena L. ,   Moscow Polytechnic University (Moscow, Russian Federation)
Published: January 2021

The article summarizes the practice of Russian publishers in the formation of the repertoire of graphic novels. In the modern world, visual perception of information is becoming an increasingly common way of obtaining and processing information. Graphic novels are forming an important part of contemporary culture in general and literature in particular, occupying a larger niche in the contemporary literary market. Publishers are trying to meet the needs of readers and include more and more series with graphic novels in their repertoire. The most successful projects in the publishing houses Bubble, Jellyfish Jam, Zodiac, 42!, Komil’fo, AST, specializing in graphic novels, are analyzed. The expansion of this book segment is continuous and quite fast. Summarizing the repertoire policy of Russian publishers, it can be asserted that graphic novels come to play an increasingly important role in modern society and in the modern book market, and they will be equal in importance to classical book editions in the future. Every year the number of graphic novels by Russian authors in the book market is growing. The repertoire of Russian publishers engaged in the production of graphic novels is quite diverse. Specialized publishers pay more attention to the projects produced, due to which there are fewer errors in the production of graphic novels in these publishers. The number of publications produced per year in specialized publishing houses is small, compared with large universal publishers. Projects of specialized publishers are more carefully selected, are often original or little-known in Russia. Each project of graphic novels by foreign authors is unique for a certain publishing house, and is not released in other publishing houses. The spread of circulations in specialized publishing houses is quite wide and often depends on the features of the project, the author’s fame, the features of the publication, as well as the niche of the publishing house. Large universal publishers mainly focus on graphic novels of widespread popularity, as a rule, within the Marvel, DC universes. All publishers considered in the study have a clear principle of development of their repertoire; in specialized publishers, the selection of projects is much more thoughtful, and each project is given more attention.
El cambio en la noción de lectura: Carlos Rincón y la práctica de la teoría literaria
Authors: Valdivia Pablo
Published: January 2021

Este artículo parte de la hipótesis que los diferentes aportes teóricos de la obra de Carlos Rincón parten de una preocupación inicial por la lectura. La lectura, en tanto práctica cultural y objeto de teoría literaria, además de permitir un diálogo de muy diversas metodologías es manifestación de una posicionalidad latinoamericana que no se define de manera esencialista, sino como actitud crítica.
Constelaciones y simulacros: Walter Benjamin y Jorge Luis Borges en la obra de Carlos Rincón
Authors: Escobar Juan David
Published: January 2021

Este artículo reflexiona sobre la relación que Carlos Rincón estableció con dos de sus autores predilectos: Walter Benjamin y Jorge Luis Borges. Esto se realiza a partir del análisis del funcionamiento del concepto de “constelación” y de “simulacro” en las concepciones que Carlos Rincón tuvo sobre la historia, la escritura y el ejercicio académico. Además de los puntos de intersección con Benjamin y Borges, se ejemplifica lo mencionado anteriormente mediante la revisión de la estructura de uno de los últimos libros que el intelectual colombiano editó en vida: María la de El Paraíso. El juicio televisivo de la novela de Jorge Isaacs: los ecos y el dolor de lo que pudo haber sido y no fue.
Silencio y contemplación: rasgos de lo místico en la poesía de Jorge Cadavid
Authors: Clavijo Daniel
Published: January 2021

A partir de los rasgos que permiten una delimitación de la idea de lo místico, este artículo indaga en la estrecha relación entre lenguaje poético y mística en la obra del poeta Jorge Cadavid. Tras una revisión de los aportes teóricos de diversos autores a la caracterización del concepto de mística, se emprende el análisis de los poemas de Cadavid a la luz de las nociones de silencio –tanto en las posibilidades de tematización como en los mecanismos retóricos y de enunciación por los cuales el silencio ingresa en el poema– y de contemplación, entendida como la mirada atenta.
Presentación: Carlos Rincón. Lector, crítico, fabulador
Authors: Sánchez Lopera Alejandro , Escobar Juan David
Published: January 2021

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Caracterización de los recobros realizados por Secretaria Seccional de Salud y Protección Social de Antioquia al FOSYGA por atenciones NO POS. 2010 – 2013
Authors: Vargas-Peña Gilma Stella , Ruíz-Sánchez Laura Estefany
Published: January 2021

Objetivo: Caracterizar los recobros realizados por la Secretaría Seccional de Salud y Protección Social de Antioquia (SSSPSA) al Fondo de Solidaridad y Garantía, por atenciones No pos entre 2010-2013. Metodología: Se realizó un estudio descriptivo retrospectivo, según información oficial suministrada por la SSSPSA, teniendo en cuenta el total de facturas recobradas (894), por $7 815 241 869. Resultados: 1) las facturas recobradas disminuyeron del 56 al 9 %, con variación negativa de –84 %; los valores recobrados disminuyeron del 51 al 15 %, con variación negativa del –71 %, y los pacientes implicados tuvieron una variación negativa de –79 %; 2) las facturas avaladas pasaron de 81 a 3 %, con variación negativa de –96 %; los valores, del 56,9 al 15 %, con una variación negativa de –79 %, y los pacientes con valores avalados, con variación negativa de –95 %. La glosa fue del 60 %, y solo se reconoció el 5 % de las respuestas. Predominaron recobros y avales para medicamentos, con el 67,5 y 61 % respectivamente. Estuvieron comprometidas 17 instituciones y 399 pacientes, con promedio de 2,2 facturas / paciente. Conclusión: Disminuyeron las solicitudes de recobro y los avales, y predominaron los medicamentos como evento recobrado y avalado. El alto porcentaje de glosa y la baja recuperación por las respuestas, hacen el proceso ineficiente e inefectivo, retardando los pagos a las instituciones prestadoras de salud y aumentando el riesgo de crisis hospitalaria, con consecuencias negativas para la salud y la salud pública de la población.
Access to Court as a Determinative Procedural Act for the Exercise of Justice and Protection of Rights in Civil Cases (Part 2)
Authors: Uksusova E. E.
Published: January 2021

The author, following the focus of the study on specialization of civil procedural law in the Russian legal system as manifested regularity of its development, relying on the inevitable dualism and interaction between material and procedural law, comprehends its current state on the example of certain basic procedural and legal institutions: the institution of the right of access to court, the institution of protection of the rights and interests of other persons, the institution of jurisdiction, etc The author’s use of known and proposed legal constructions, categories and concepts in the author’s combination and (or) interpretation makes their research urgent for the purposes of understanding of the key conditionality of civil procedural law specialization in the Russian law system as providing them with the administration of justice and protection of rights in civil cases in compliance with their wide understanding when the right to judicial protection in the system of constitutional rights and freedoms constitutes a guarantee for all of them. This paper is the second in a series of three papers devoted to the problem of the right of access to court as the most important issue of dualism and interaction between material and civil procedural rights.
Prospective Directions of Prosecutor’s Offi ce Activity in Enhancing the Institution of Independent Anti-Corruption Expertise
Authors: Borodina O. A.
Published: January 2021

One of the measures to prevent corruption in Russia is the anti-corruption expertise of regulatory legal acts and their drafts. This is the only measure aimed at eliminating the causes of corruption in the field of lawmaking. The prosecutor’s office is considered to be the most effective body to implement it. The Institute of Independent Anti-Corruption Expertise has not been operational today as far as is necessary. In the course of the research, some prosecutors and accredited independent experts were surveyed. Both groups of respondents proved the effectiveness of this preventive measure, noting that it needs improving. As part of the study, the author attempts to identify the problems faced by independent experts, as well as the prosecutors themselves, and proposes ways to solve these problems and enhance independent experts by means of the prosecutor’s office activities. The study showed that it is necessary to improve the conceptual apparatus of the legal institution (e.g., the lack of definitions of “corruption” and “corruptogenic factor”), the mechanism of interaction between prosecutors and independent experts when conducting anti-corruption expertise of both existing acts and projects. Prosecutors can play a coordinating role with a clearer departmental regulation of this activity, take measures of moral encouragement of independent experts, most actively report on their work in carrying out anti-corruption expertise, while involving independent experts in it. Additional regulation of this activity is necessary at the level of both federal law and organizational and administrative documents of the Prosecutor General of the Russian Federation. According to the study, 63% of independent experts named the improvement of the mechanism of their participation in anti-corruption expertise as one of the main factors in enhancing their activities.
On some classes of inverse problems with point overdirection for mathematical models of heat and mass transfer
Authors: Baranchuk Vladislav A. , Pyatkov Sergey G.
Published: January 2021

The paper considers the question of the correctness in Sobolev spaces of inverse problems of recovering the function of sources of a special form for mathematical models of convection-diffusion and heat and mass transfer. Unknown time-dependent functions are included in the source function. The values of the solution in a certain set of points of the region lying both inside the region and on its boundary are considered as conditions for redefining. Conditions are given that guarantee the global correctness of the problem in Sobolev classes. The conditions for these tasks are minimal. The results are accurate.
Software development for solar hybrid inverter management and monitoring
Authors: Godovnikov Evgeniy A. , Korotkov Mikhail G. , Tatyankin Vitaliy M.
Published: January 2021

This article discusses the development of software for the diesel generator limitation controller as part of a hybrid solar power plant system. контроллера ограничения работы дизель-генератора

In the course of the work, a block diagram of the system was proposed, and the controller software was described in detail.

The aim of this work is to reduce the operating time of a fuel generator by limiting its operating time depending on the battery charge level and time of day.
Problems of identifying time series intervals when predicting the dynamics of the number of infected Covid-19 by statistical methods using the example of Yugra
Authors: Korotkov Mikhail G. , Petrov Aleksey A. , Kurkina Maria V.
Published: January 2021

The aim of this work is to develop an approach to isolate the data interval for statistical forecasting from the time series of dynamics of new cases of coronavirus infection in the Yugra of the number of COVID-19 infected in the spring-summer of 2020.
Prácticas de alto impacto y aprendizaje activo para la adquisición de competencias específicas en botánica
Authors: Acedo Carmen , Alfaro-Saiz Estrella , Alonso Yasmina , Fernández-Salegui Ana B. , Fernández-Santos Darío , González-Sierra Graciela , Lence Carmen , Lois Raúl , Pérez-Llamazares Alicia , Santamarina Sara , Trobajo Sonia
Published: January 2021

Una gran variedad de tareas cooperativas y de aprendizaje activo son parte de las actividades formativas de las asignaturas en las que estamos involucrados los profesores del Grupo de Innovación Docente para la Adquisición de Competencias en Botánica Sistemática y Conservación (GID ACBoSCo). Cada actividad se organiza y construye para incentivar a los estudiantes en el proceso de aprendizaje, así como para ayudar a desarrollar habilidades útiles para su futuro profesional (docente, técnico o de investigación). La organización y la planificación de estas tareas, son vitales, al igual que trabajar en grupos pequeños y los incentivos adecuados para completarlas. Entre las actividades destacadas, las tareas de aprendizaje servicio, como la preparación de materiales formativos que se ponen a disposición del curso, el diseño de actividades virtuales de laboratorio, para conocer, aunque sea de forma básica, protocolos específicos a distancia, la gamificación, para despertar interés y curiosidad por las disciplinas, u otras actividades educativas de alto impacto como la formación avanzada con expertos, actividades al aire libre, o tareas de microlearning, complementan la formación tradicional, y resultan esenciales. Además, muchas de estas actividades demostraron ser una herramienta potente para adaptar algunos contenidos de las asignaturas al entorno formativo virtual y con ello poder hacer frente a la docencia Covid-19 fomentando el aprendizaje activo de los alumnos, lo que se puso de manifiesto en los excelentes resultados obtenidos en estas asignaturas.
Comentando El sentido del progreso desde mi obra. Miguel Delibes Setién, 1975. Discurso de ingreso en la Real Academia Española
Authors: Calabuig Estanislao Luis
Published: January 2021

Con este tipo de interrogantes justifica Miguel Delibes dedicar su discurso de ingreso en la Real Academia Española (Delibes, 1975) a la protesta contra la brutal agresión a la Naturaleza que las sociedades llamadas civilizadas vienen perpetrando mediante una tecnología desbridada (r.e. 1) (Fig. 1). Quizá sea pertinente, antes de proseguir con el comentario, argumentar algunas razones que me han inducido a incluir este análisis en este momento. Una de ellas está relacionada con la oportunidad, ya que el pasado 17 de octubre de 2020 se celebraban los cien años del nacimiento del insigne escritor y periodista. Otra se explica por su tenaz defensa de los valores ambientales, pero, ¿por qué dedicarlo, precisamente con ese contenido, al discurso de ingreso en la RAE y no a cualquier otra obra de su extensa producción? La oración solemne de incorporación de los académicos es de libre elección, y precisamente el tema que se elige suele estar precedido de una meditada exploración de posibilidades y de una razonada conclusión. Cualesquiera que fueran esos prolegómenos, la decisión final fue dedicarla al sentido del progreso. Progreso que se puede asimilar, en la terminología actual a desarrollo, término científico que ha ocupado una gran parte de las preocupaciones de los científicos que dedican su estudio e investigación al medio ambiente desde cualquiera de sus posibles vertientes. Por lo tanto, de plena actualidad en el desarrollo de los objetivos y competencias de una Facultad como la de Ciencias Biológicas y Ambientales de la Universidad de León. Resulta muy atractivo para nosotros, los que estamos implicados en el estudio de los sistemas naturales, que un escritor consagrado presentara un tema específicamente enfocado en su oratoria a la denuncia del impacto del desarrollo en las relaciones entre la Especie Humana y la Naturaleza, e impregnado de instrucciones para tratar de entender el funcionamiento de la Naturaleza.
De todo un poco
Authors: UNILEON OJS Administrador
Published: January 2021

La excepcional situación provocada por la COVID-19 durante este año 2020, ha obligado a suspender o modificar muchas de las actividades en las que de forma habitual participa la Facultad de Ciencias Biológicas y Ambientales (FCCBA) de la Universidad de León (ULe). A pesar de ello, y en la medida de lo posible, hemos continuado colaborando y organizando eventos tanto de carácter científico y cultural como formativo y divulgativo.
Powder Loading Effects on the Physicochemical and Mechanical Properties of 3D Printed Poly Lactic Acid/Hydroxyapatite Biocomposites
Authors: L. Custodio Cyron , M. Broñola Phoebeliza Jane , R. Cayabyab Sharyjel , U. Lagura Vivian , R. Celorico Josefina , A. Basilia Blessie
Published: January 2021

This study presents the physicochemical and mechanical behavior of incorporating hydroxyapatite (HAp) with polylactic acid (PLA) matrix in 3D printed PLA/HAp composite materials. Effects of powder loading to the composition, crystallinity, morphology, and mechanical properties were observed. HAp was synthesized from locally sourced nanoprecipitated calcium carbonate and served as the filler for the PLA matrix. The 0, 5, 10, and 15 wt. % HAp biocomposite filaments were formed using a twin-screw extruder. The resulting filaments were 3D printed in an Ultimaker S5 machine utilizing a fused deposition modeling technology. Successful incorporation of HAp and PLA was observed using infrared spectroscopy and X-ray diffraction (XRD). The mechanical properties of pure PLA had improved on the incorporation of 15% HAp; from 32.7 to 47.3 MPa in terms of tensile strength; and 2.3 to 3.5 GPa for stiffness. Moreover, the preliminary in vitro bioactivity test of the 3D printed PLA/HAp biocomposite samples in simulated body fluid (SBF) indicated varying weight gains and the presence of apatite species’ XRD peaks. The HAp particles embedded in the PLA matrix acted as nucleation sites for the deposition of salts and apatite species from the SBF solution.
Viktor Frankl: Para Além de suas Memórias
Authors: AQUINO Thiago Antonio Avellar de
Published: January 2021

The research aimed to analyze Frankl's book "What is not written in my books". The latter is considered the most important self-biographical material by this author, considering that it's relevant to understand to which extent his life and work are related. The research corpus has been processed through the R Interface for Multidimensional Analysis of Texts and Questionnaires (IRAMUTEQ) software through the procedure of similarity analysis and word cloud. Thus, the most frequent words were "say" and "do", which, by the same token, formed two structures of meaning. The analysis procedures revealed an existential coherence between the life and the work of the author, which helped to expand the understanding on the meaning of life of Viktor Frankl.
Experiências Anômalas e Dissociativas em Contexto Religioso: Uma Abordagem Autoetnográfica
Authors: MARALDI Everton de Oliveira
Published: January 2021

The present study explored the phenomenological characteristics of anomalous experiences (AEs) reported during Umbanda rituals, a mediumistic Brazilian religion, with the aim of comparing AEs reported during rituals involving the use of Ayahuasca (an entheogen frequently used in some Umbanda contexts) and rituals without the use of this substance. In order to do so, we compared individuals with different levels of involvement with the mediumistic practices. The study was based on an auto-ethnographic approach. This methodological perspective allowed us to confront subjective data with the available knowledge in the scientific literature about AEs, dissociative phenomena and altered states of consciousness and was of fundamental importance for a more sensitive understanding of the nuances and characteristics of these experiences. The results attest to a significant similarity between the experiences reported with and without the use of Ayahuasca in mediumistic contexts. In both groups, the experiencers were able to identify certain similarities in their experiences regarding a reduction of voluntary motor control, changes in memory and perception, communicability and accessibility of experiences, anomalous information reception and increases in interpersonal sensitivity. The results support the methodological feasibility of autoethnography as a research tool and point to its relevance to a deeper understanding of AEs and other subjective experiences usually of difficult investigation by other research methods.
El camino hacia una nueva antropología clínica: afectividad y corporalidad en la obra de erwin straus
Authors: MENDL Sebastián Eduardo
Published: January 2021

From a hermeneutic reading of the phenomenological anthropology of Erwin Straus, current work seeks to explain the original meaning of affectivity and corporality, as constituting modalities of the relation between human existence and its world. On the first term, through a critical-historical reconsideration of certain propositions of scientific psychology and their philosophical foundations, the aim is to go back to the origin of human condition, deformed by interpretations founded on suppositions a priori, uncovering it. Precisely, opposite to current naturalistic psychology, fades off the ontological difference between man and things, from a perspective as Straus', the incarnated subjectivity, which feels itself when it feels something else, is proposed as the primary object of study of psychological science; its own action is exposed continuously to other influences, therefore, its intrinsic vulnerability. The present analysis allows us to establish a new frame, both for the future experimental investigations and for the comprehension of the experience of the alienated man. Indeed, Straus' phenomenological anthropology allows us to break off the three dualisms that support contemporary investigations of corporality and affectivity: subject-object, receptivity-activity, interior-exterior. Secondly, psychopathologies are understood as different modalities of I-world relations, fully significative in which the impossibility of existence to decide on the course of his biography prevails.
Angústia como Constitutiva da Existência: Ressonâncias para a Clínica Psicológica
Authors: SILVA Ellen Fernanda Gomes da , BARRETO Carmem
Published: January 2021

This article aims to present the understanding of the anguish as constitutive of human existence, from the hermeneutic phenomenology. In this perspective, we intend to weave comprehensive possibilities that may present resonances to think the psychological clinic as a possible place of reception of the anguish. For this, we will talk with some dimensions of the thinking of Kierkegaard, Heidegger and Boss, in the search for subsidies that, because they present another possibility of understanding of anguish, not tied to theoretical-explanatory premises, make it possible to think of the clinical action linked to the original mode as the existential phenomena happen.
Percepção como experiência subjetiva na constituição do mundo-da-vida na fenomenologia de Husserl
Authors: BARRETO Jaime Javier Villanueva
Published: January 2021

This work aims to show the determining role of perception in the constitution of Lifeworld and how it, despite the diversity of perceptual experiences, maintains its unity. The aim is to show, through a tour of the main works of Husserl, the profound relationship between perception and the constitution of the meaning of the unique world. The world understood as horizon allows us to retrospectively advance to the constitutive experiences among which the original lived experience of perception prevails. This highlights the subjective experience in the constitution of meaning of the Lifeworld.
Compreensão do Binômio Segurança e Risco: Perspectivas em Diálogo
Authors: CAMPOS Rafael Cidrão , MAIA João Vitor Moreira
Published: January 2021

The paper seeks to develop an understanding of the creative adjustments of maintaining the status quo and security and the impossibility or non-existence of security as risk-free. Despite this impossibility, the search for safety and risk avoidance are striking in contemporary society and often present in the psychological clinic. This is often understood as a space that will provide answers and security in the imagination of both the seeker and the psychotherapist. Reflecting on the subject, we seek to establish a dialogue between sociological perspectives, the philosophy of Paul Tilich and the theoretical references of Gestalt Therapy. It is argued that, from modern societies, scientific knowledge, including psychology, is sought as a promise of security. From Paul Tilich's work, risk is pointed out as inherent in existence, illustrated by the certainty of death. It is also indicated that anxiety is experienced by man in the face of awareness of his finitude, and this anxiety can be faced by an act of courage. It is resorted to the theoretical framework of Gestalt Therapy, which considers the fantasy of safety and avoidance of risk as possible neurotic adjustments, understood as obstacles to growth by avoiding contact with novelty. It also notes that the clinical practice of Gestalt therapy is not intended to offer an absence of risks to its clients, but, supported by the environmental support built in the therapeutic relationship, seeks to facilitate contact with the way these risks are lived, thus enabling the development of self-support.
Willingness to Pay Analysis of First Fuel in Yogyakarta
Authors: Khairunnisa Masniya , Setiartiti Lilies
Published: January 2021

This study aims to measure the value of willingness to pay and analyze the factors that affect consumer willingness to pay toward Pertamax fuel. This study's dependent variable is income, number of owned vehicles, the frequency of vehicle use, and product literacy. In this study sample of 100 Pertamax fuel users in Yogyakarta were selected using the Purposive Sampling method. This study using multiple linear regression or Ordinary Least Square (OLS). The results show that the value of consumer willingness to pay toward Pertamax fuel is Rp. 10,545. The factors that influence willingness to pay are income, frequency of vehicle use, and product literacy. These three variables are positive and have a significant influence on consumer willingness to pay toward Pertamaxfuel. While the variable number of the owned vehicle
ADA activity in the follicular fluid of infertile women with diminished ovarian reserve can act as a predictor of ovarian reserve
Authors: İlhan Gülşah , Bacanakgil Besim H. , Köse Ayşe , Atıcı Ayben , Yalçınkaya Şener , Ayyıldız Mevlüde
Published: January 2021

Background: Adenosine deaminase (ADA) catalyses the deamination of adenosine to inosine. In the human reproductive tract, the importance of enzymes that affect metabolism of adenosine, particularly ADA, has been emphasized. It is aimed to evaluate the plasma and follicular fluid (FF) activities of total ADA (ADAT) in infertile women and to determine its relation with ovarian reserve markers and in vitro fertilization (IVF) outcomes.Methods: Plasma and FF activities of ADAT were measured in 106 infertile women. Its relation with ovarian reserve markers and IVF outcomes were determined.Results: There was a significant difference in the ADAT activities between plasma and FF of infertile women (p<0.01). The activity of plasma ADAT was higher than FF ADAT in infertile women (p<0.01). The activity of FF ADAT in DOR group was higher than that of the others (p<0.01). In DOR group; the activity of FF ADAT activity had a negative correlation with BMI and a positive correlation with FSH and no relation with IVF outcomes.Conclusions: Increased ADAT activity can lead to reduced adenosine levels, which might be resulted in disturbed fertility process. The activity of FF ADAT activity might be important for fertility work-up. Further studies are needed.
Correlation of mature mean follicle on transvaginal ultrasound and serum estradiol levels on day of trigger injection of ovulation in ovarian stimulation cycle of in vitro fertilization with retrieved oocytes
Authors: Kapoor Avnika , Sharma Garima , Bakshi Rita
Published: January 2021

Background: Controlled ovarian hyperstimulation aims to obtain mature follicles. The present study was conducted to assess the correlation of mature follicle in transvaginal ultrasound scanning (TVS) and serum estradiol levels on day of trigger injection in ovarian stimulation cycle for IVF with the oocyte yield.Methods: In this prospective study, we evaluated oocyte donor 19 to 45 years of age who underwent oocyte retrieval at our clinic. Outcome variables like number of mature follicles visualized on TVS on the last day of stimulation was noted for all patients. On the same day, serum estradiol levels and number of mature follicles seen on TVS were noted and correlated with the number of oocytes retrieved. Ultrasound guided transvaginal oocyte retrieval was performed and total number of oocytes were noted.Results: During the study period, 20 oocytes donors were included. Mean age of the patients was 27.9±4.7 years. Mean BMI was 26.8±2.3 kg/m2. Mean FSH level was 6.89±1.79 IU/L and mean antral follicle count on day 3 was 14.06±3.56. On the day of trigger, mean mature follicle count seen on TVS was 20.4±13.8, ranging from 8 to 50. On an average, 17.2 oocytes were retrieved. On the day of trigger, mean estradiol level was 4970±203, ranging from 500 to 15,665 pg/ml. It was observed that the number of retrieved oocytes correlated significantly with the serum estradiol levels, (Pearson’s coefficient 0.94, p value<0.001) and number of mature follicles seen on TVS ((Pearson’s coefficient 0.92, p value<0.001).Conclusions: Number of retrieved oocytes correlated significantly with the serum estradiol levels and number of mature follicles seen on TVS on the day of trigger.
Comparison of ovarian crescent sign and risk of malignancy index for prediction of ovarian malignancy in adnexal masses
Authors: Sharma Abha , Sharma Richa , Gulati Ashita
Published: January 2021

Background: Objective of the study was to evaluate ovarian crescent sign (OCS) as a sonographic parameter for prediction of ovarian cancer in adnexal masses suspicious of ovarian malignancy and to compare it with risk of malignancy index (RMI).Methods: Presence of OCS and calculation of RMI was done for 50 cases of adnexal masses scheduled to undergo surgery taking histopathology as gold standard.Results: 18% (9/50) of adnexal masses were malignant. OCS was absent in all malignant lesions, giving a sensitivity and negative predictive value of 100%. OCS was present in 33/41 of benign masses (specificity 80.4%). Relation of OCS to mass size<10 cm and menopausal status was significant (p<0.001). RMI≥200 could not diagnose malignancy in 4/9 cases (sensitivity 55.5%). RMI had specificity and negative predictive value of 95.1% and 90.7% respectively. Combining OCS and RMI had a lower specificity. Sequential application using OCS as first node and RMI as second node failed to diagnose 44.4% (4/9) cases as malignant.Conclusions: OCS is cheaper, easy to perform and appears to be a better test than RMI to differentiate between benign and early-stage malignant ovarian tumors. It can be used for triaging patient for referral.
Impact of maternal pre-pregnancy body mass index on neonatal outcomes: a hospital based study in a tertiary care hospital in Goa
Authors: Naik Rini , Karmali Deepa , Nagarsenkar Ajit , Mainath Sneha , Pednekar Guruprasad
Published: January 2021

Background: Maternal under-nutrition as well as obesity, both are known to have adverse effects on the perinatal outcomes. In developing countries like India wherein the burden of both under-nutrition and obesity is rising, there is a need to spread awareness regarding the need to achieve adequate weight prior to pregnancy. Thus, this study was undertaken to observe effect of maternal pre-pregnancy BMI on neonatal outcomes in Goa Medical College (GMC) during the time period from December 2018- December 2019.Methods: A hospital based retrospective observational study was conducted wherein the neonatal outcomes of 3940 women delivering in Goa Medical College during the time period of 1 year were studied. All the study participants were divided into five groups depending upon their BMI calculated at the first antenatal visit in the first trimester.Results: Most of the women in our study were in the normal BMI category (49.8%), however a large number were overweight (37.3%), 3.2% were obese and 0.1% were morbidly obese and 9.6%were underweight. The neonates born to underweight mothers were mostly low birth weight (66.6%) while macrosomia was more common in those born to obese (3.1%) and morbidly obese (25%) women. Neonatal complications like birth asphyxia, respiratory distress syndrome and hypoglycaemia were found in significantly higher proportion in both underweight as well as obese groups. These complications were responsible for a higher NICU admission rate and a higher neonatal mortality observed in both underweight as well obese group of mothers.Conclusions: Thus in view of the poor neonatal outcomes observed in both extremes of maternal BMI, it is the need of the hour to establish better nutrition programs and educate our women regarding the necessity to achieve adequate pre-pregnancy BMI to improve the pregnancy outcomes.
Fetal and maternal outcome in oligohydramnios pregnancy (37-40 weeks)
Authors: Joshi Suyajna D. , Banu Ruksar , Rai Rajeswari , G. Jayasakthi
Published: January 2021

Background: This study is conducted to see the effects of oligohydramnios on both mother and fetus.Methods: 237 antenatal patients delivered at Department of DNB-OBG District hospital Bellari during January 2018 to December 2018 with gestational age between 37-40wks with AFI<5cms with intact membranes were studied and analyzed retrospectively for perinatal and maternal outcome.Results: Out of 237 cases with oligohydramnios with AFI <5cm studied, about 229 cases underwent LSCS (96.6%). most are primigravida about 164(69.19%), belong to age group of <25 about 181(76%). Average gestational age noted to be 38+4 weeks about 55.9% (132), NICU admission seen in 47(19.8%) of total cases. Most of the babies delivered are >2.5 kg birth weight about 144 (60.75%) of cases.  New born with APGAR <7 @ 1 min seen in 36 cases (15.15%). Meconeum stained liquor seen in about 70 cases (29.5%).Conclusions: Oligohydramnios has significant correlation with increased Caesarean section for fetal distress. Oligohydramnios is associated with high rate of pregnancy complication and increased rate of NICU admission. Oligohydramnios is a frequent occurrence demanding careful evaluation, intensive fetal surveillance and proper antepartum and intrapartum care.
Perinatal outcome of meconium stained amniotic fluid in pregnancy beyond 37 weeks
Authors: Suyajna Joshi D. , G. Jayasakthi , Rai Rajeswari , Banu Ruksar
Published: January 2021

Background: To identify the frequency of meconium aspiration syndrome among the total births who suffered from meconium staining of amniotic fluid, to find out risk factors during pregnancy, therapies and various complications associated with this condition and their effects on perinatal outcome.Methods: This was a retrospective study of 252 antenatal patients delivered at Department of DNB-OBG District hospital Bellary during the year January 2019 to December 2019 with gestational age between 37-40 weeks with singleton pregnancies and cephalic presentation were included in the study.Results: The Caesarean section rate for fetal distress was 96.6% in patients with meconium stained amniotic fluid (MSAF). Meconium aspiration syndrome (MAS) was found in3.93% babies. APGAR score at 1 minute <7 was found in 25 cases (9.84%).Conclusions: Meconium stained amniotic fluid is associated with increased need for neonatal resuscitation, increased risk of birth asphyxia, meconium aspiration syndrome, hospital admission and mortality. So identification of pregnant woman at risk of passage of meconium during labour would allow intensive fetal surveillance and early intervention which might lead to reduction in neonatal adverse outcome.
Assessment of tubal patency through sono-hysterosalpingography using B-mode and colour Doppler: a comparative study
Authors: Gupta Bhavini , Pasoria Sanjay , Manmohan Madan
Published: January 2021

Background: Tubal factors constitute a major proportion of infertility causes, and include disorders affecting one or more components of the fallopian tube. Demonstration of tubal patency using imaging modalities can help lower the rate of invasive diagnosis and management. Hysterosalpingography provides optimal delineation of fallopian tube anatomy, allowing detection of tubal patency, tubal occlusion, and peri-tubal disease. Sonosalpingography with saline infusion was started as an alternative because of its added benefits of structural and morphological abnormality detection.Methods: Patients referred for primary and secondary infertility were assessed on B-mode ultrasound trans-abdominally, followed by cervical catheterization and trans-vaginal ultrasound. Sterile saline fluid was pushed through the cervix, to use as a contrast medium, and its movement was assessed on B-mode and as a colour Doppler artefact.Results: B-mode, colour Doppler and presence of free-fluid in pouch of Douglas showed presence of tubal patency in 59.6%, 82.7% and 78.8% cases respectively and presence of bilateral and unilateral tubal block in 60.4%, 17.3% and 21.2% respectively. Diagnostic accuracy of B-mode and colour Doppler is 84.6% and 95.2% respectively.Conclusions: Sonosalpingography can be used to pin-point the exact location of the tubal block, due to its real-time imaging benefits. Normal saline infusion can be used effectively. Colour Doppler provides higher sensitivity for evaluation of tubal patency and has higher specificity for tubal block. Used in combination, they improve diagnostic accuracy and efficacy of sonosalpingography.
Fetomaternal outcomes in conservative management of preterm premature rupture of membrane
Authors: Chundawat Rama , Singh Meenakshi , Gupta Arun , Jakhetiya Bhamini , Khan Ruhina
Published: January 2021

Background: The management of PPROM remains controversial. Aim of this study was to determine the fetomaternal outcome in conservative management of PPROM.Methods: A prospective observational study was done on a total of 110 pregnant women between 24 and 36 weeks 6 days gestation with PPROM visiting Geetanjali medical college and hospital from February 2019 to July 2020. All the patients were subjected to detailed history and examination and followed till their delivery.Results: The incidence of PPROM in our study was 4.94%. The mean latency period from membrane rupture to delivery decreased from 12.1±14 days at >28 weeks, 5.3±7.7 days at 28-31 weeks 6 days to 1.1±1.2 days at 32 to 36 weeks 6 days. The most common indication of LSCS was fetal distress (26.31%). E. coli was the most common organism (36.36%) isolated and it was significantly associated with gestational age at PPROM (p value <0.040405). The maternal morbidity was 24.53% and was closely associated with the gestational age at PPROM (p value <0.001). The perinatal morbidity was 44.20% and perinatal mortality was 13.04% which was mainly due to RDS (33.34%).Conclusions: Management of PPROM involves complete evaluation of risks and benefits of conservative management. The treatment should be directed toward conserving the pregnancy with prophylactic use of antibiotics and corticosteroids thereby reducing fetomaternal morbidity and mortality. However, termination of pregnancy should be considered at the earliest suspicion of chorioamnionitis, septicaemia.
A rare case of secondary abdominal pregnancy following ruptured rudimentary horn
Authors: Sreenivas Anju , Diana G. Valsa
Published: January 2021

Abdominal pregnancies are classified as primary or secondary of which secondary abdominal pregnancies are more common. The incidence of abdominal pregnancy varies from 1 in 372 to 1 in 9,714 live births and accounts for 1.4% of ectopic pregnancies. Rudimentary horn pregnancy occurs in approximately 1/76 000 to 1/150 000 pregnancies. Abdominal pregnancies are classified as primary or secondary of which secondary abdominal pregnancies are more common. The incidence of abdominal pregnancy varies from 1 in 372 to 1 in 9,714 live births and accounts for 1.4% of ectopic pregnancies. Rudimentary horn pregnancy occurs in approximately 1/76 000 to 1/150 000 pregnancies. We report a case of secondary abdominal pregnancy in a 24-year-old primigravida at 19 weeks gestation who was asymptomatic on admission but a known case of unicornuate uterus with rudimentary right horn. Ultrasound revealed fetus in the abdominal cavity and was confirmed by MRI. Intraoperatively, fetus was found en sac in abdominal cavity and placenta in the cavity of the ruptured right rudimentary horn which was removed in toto with the horn.
A study of dysnatremia in patients admitted in medical intensive care unit of a tertiary care teaching hospital
Authors: Patel Mantavya , Paliwal Sanjay Kumar , Javed Syed
Published: January 2021

Background: Both dysnatremia at admission and that acquired in the intensive care unit (ICU) have been shown to have a direct influence on prognosis. The present was planned to study dysnatremia in adult patients admitting in medical intensive care unit (MICU).Methods: The present prospective observational study was conducted on patients admitted in medical ICU over a period of 1 year who developed dysnatremia during ICU stay. Patient’s age, sex, diagnosis at the time of diagnosis, comorbidities, serum sodium levels, risk factors, length of ICU stay, and survival status were noted.Results: Out of total 798 patients during the study period; 207 (25.94%) were found to have hypernatremia and 87 (10.9%) were hyponatremic. In hypernatremic group male/ female ratio was 125/82 and it was 50/37 in hyponatremic group. The mean ICU stay was significantly more in hypernatremic patients (4.76±3.57) compared to hyponatremic group (4.06±2.80). (p˂0.05) Mortality in both hypernatremic patients and hyponatremic patients was found significantly more in hypervolemic group which was 84.38% and 53.84% respectively. (p˂0.05)Conclusions: This study concluded that nowadays hypernatremia is more common with longer ICU stay. In both hypernatremia and hyponatremia mortality was found similar without any significant difference.
Rapid differential diagnostic methods of meningitis in adults
Authors: Nipanal Akkamahadevi V. , H. Nagappa
Published: January 2021

Background: Acute infections of the nervous system are among the most importantproblems in medicine because early recognition, efficient decision making, and rapid institution of therapy can be lifesaving. Objective of the present study was to find out the usefulness of these two tests, CSF-ADA and CSF-CRP for the rapid diagnosis and differentiation of bacterial, tubercular and viral meningitis in adults.Methods: Fifty meningitis patients were selected after fulfilling the following inclusion and exclusion criteria. A prospective clinical evaluation study is undertaken to study the predictive value of CSF CRP and ADA in relation to various types of meningitis.Results: More than half the cases reported were of tubercular meningitis, followed by viral and pyogenic meningitis. The percentages of tubercular, viral and pyogenic were 52%, 32% and 16% respectively. CRP levels were elevated in pyogenic meningitis; the mean CRP level was 25.26±5.56 mg/dl. ADA activity was found to highest in tubercular meningitis, the mean value was 17.67±8.13 IU/L.Conclusions: Study concluded that combine use of CSF CRP and ADA can be used for early differentiation of bacterial, tubercular, and viral meningitis.
Systemic sclerosis: a rare presentation
Authors: Karamoy Elvi Aprillia , Hotama Jason Raymond , Suryana Ketut , . Novitasari
Published: January 2021

Systemic sclerosis or so called scleroderma is an uncommon autoimmune inflammatory and fibrotic connective tissue disease involving multiple organs. The etiology of systemic sclerosis is currently unknown and its pathogenesis is only partially understood. Skin thickening and Raynaud’s phenomenon are the most common symptoms. Although systemic sclerosis is uncommon, it is associated with high morbidity and mortality. In this report, we present a case of a-43-year-old man with the complaint of weakness, tightening of the skin over the fingers, tingling in the soles of feet, nausea and significant weight loss. Laboratory examinations revealed positive ANA test, but negative anti topoisomerase I (anti-Scl-70), and anticentromere antibody.