bluuebunny/crossref_metadata_2025 huggingface dataset:
Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 4 (fresh‐cut FVH process water management plan)
Authors:   EFSA Panel on Biological Hazards (BIOHAZ), Allende Ana , Alvarez‐Ordóñez Avelino , Bortolaia Valeria , Bover‐Cid Sara , De Cesare Alessandra , Dohmen Wietske , Guillier Laurent , Herman Lieve , Jacxsens Liesbeth , Mughini‐Gras Lapo , Nauta Maarten , Ottoson Jakob , Peixe Luisa , Perez‐Rodriguez Fernando , Skandamis Panagiotis , Suffredini Elisabetta , Banach Jen , Zhou Bin , da Silva Felício Maria Teresa , Martino Laura , Messens Winy , Botteon Angela
Published: January 2025

Abstract
Water used in post‐harvest handling and processing operations is an important risk factor for microbiological cross‐contamination of fruits, vegetables and herbs (FVH). Industrial data indicated that the fresh‐cut FVH sector is characterised by process water at cooled temperature, operational cycles between 1 and 15 h, and product volumes between 700 and 3000 kg. Intervention strategies were based on water disinfection treatments mostly using chlorine‐based disinfectants. Water replenishment was not observed within studied industries. The industrial data, which included 19 scenarios were used to develop a guidance for a water management plan (WMP) for the fresh‐cut FVH sector. A WMP aims to maintain the fit‐for‐purpose microbiological quality of the process water and consists of: (a) identification of microbial hazards and hazardous events linked to process water; (b) establishment of the relationship between microbiological and physico‐chemical parameters; (c) description of preventive measures; (d) description of intervention measures, including their validation, operational monitoring and verification; and (e) record keeping and trend analysis. A predictive model was used to simulate water management outcomes, highlighting the need for water disinfection treatments to maintain the microbiological quality of the process water and the added value of water replenishment. Relying solely on water replenishment (at realistic feasible rates) does not avoid microbial accumulation in the water. Operational monitoring of the physico‐chemical parameters ensures that the disinfection systems are operating effectively. Verification includes microbiological analysis of the process water linked to the operational monitoring outcomes of physico‐chemical parameters. Although Escherichia coli and Listeria spp. could be indicators for assessing water quality, food business operators should set up and validate a tailored WMP to identify physico‐chemical parameters, as well as microbial indicators and their threshold levels, as performance standards for maintaining the fit‐for‐purpose microbiological quality of the process water during post‐harvest handling and processing operations.
ENHANCING ENGLISH WRITING SKILLS IN ENGINEERING STUDENTS THROUGH A FLIPPED CLASSROOM APPROACH.
Authors: Pathan Soebmahamed Y , Qureshi Vaseem
Published: January 2025

Students in the 21st century are looking for an educational system that supports their needs. The focus of teaching has shifted from being teacher-centered to student-centered through innovative methods. With technology and globalization advancing, strong communication skills in English are crucial for engineering students as they are key for employability. Communication is one of the 12 essential Programme Outcomes defined by the National Board of Accreditation (NBA). The four fundamental language skills—listening, speaking, reading, and writing (LSRW)—play a significant role in developing English communication abilities. While all these skills are important, writing serves as a foundation for effective verbal communication, yet it can be challenging to master without a solid grasp of the other three skills. This paper investigates how the Flipped Classroom approach can be effectively applied in English language classrooms to enhance the writing skills of 30 Third-Year B.E students, along with other essential 21st-century skills.Background: The current teaching methods have evolved from traditional lectures to incorporating cooperative and collaborative learning, along with Information and Communication Technology in English classes. Some effective approaches include computer-assisted language learning, mobile-assisted language learning, project-based and problem-based learning, flipped classrooms, and task-based language learning. The present study examines how well the flipped classroom model helps improve undergraduate students' writing skills. The study focused on a group of college students enrolled in a writing course. In the flipped classroom approach, students watched recorded lectures and completed online activities before attending in-person classes. During these classes, they worked on writing tasks with their instructor's help. The research used a mixed-methods design, which included analyzing data from tests taken before and after the course to measure changes in writing skills. It also gathered student opinions through surveys. The results suggest that the flipped classroom approach is effective in improving students' writing. The test scores showed a significant improvement in their writing skills, and the students reported that the method was engaging, flexible, and beneficial for their learning. In conclusion, this study emphasizes the potential of the flipped classroom model to enhance writing skills in undergraduate students.
THE ROLE OF COMMUNALISM IN INDIAN POLITICS –AN OVERVIEW
Authors: Vanaja
Published: January 2025

Communalism is an extremely complex phenomenon. It is generally associated with plural societies. While in the West, communalism alludes to the feelings and a concern for the community and is used in a positive sense in India the term ‘communalism’ has a negative connotation; it is used to designate the process of mobilizing a community to confront another community. More specifically communalism is regarded as a manifestation of confrontation between the minority community and the majority community. India, the multicultural and religious nation has also a very special political feature, the different caste and communal elements determining the stability and instability of the Indian politics. In India, no coalition ministry can come in to political power without the support of caste and communal groups, the caste ridden politics in India, in the context of secular state is also analyzed in this study. Here, the researcher uses the term ‘communalism’ to denote the major religion based or community based political parties and how it influences the stability and instability of the power politics of India.
Desarrollo de competencias investigativas a través de la inteligencia artificial. Un enfoque innovador
Authors: Cárdenas-Velasco Kléver , Moreira-Benavides Jesenia , Amores-Pacheco Celia , Mariela Núñez-Santiana
Published: January 2025

El artículo presenta el tema sobre el Desarrollo de competencias investigativas a través de la inteligencia artificial. Un enfoque innovador. Responde al paradigma constructivista que enfoca el aprendizaje activo fundamentado en el contexto de experiencias y el cognetivismo, plantea redes de conocimiento con manejo de tecnología para la construcción del aprendizaje. Se describen ideas que ayuden a resolver el problema actual, pues, los docentes y estudiantes no tienen el suficiente conocimiento de la Inteligencia Artificial (IA) y su relación con las competencias investigativas. El objetivo es proponer la optimización del proceso educativo con la incorporación de la IA y el desarrollo de competencias investigativas en los estudiantes. Se sustenta en contenidos actualizados sobre los dos temas principales, con énfasis en su dimensión ética. Se empleó el método analítico-sintético; el  análisis documental  y  la  revisión  bibliográfica con información científica especializada que respalda el trabajo y proyecta sus resultados a otros posibles estudios. Se concluye que existe la necesidad de incorporar la IA de manera progresiva en las instituciones educativas, en las cuales se deberá instalar el soporte virtual necesario para que se apliquen las competencias investigativas en el proceso de aprendizaje y lo puedan manejar eficientemente los docentes y paulatinamente los estudiantes. Es un requisito indispensable para lograr un mejoramiento cualitativo en los procesos educativos con la finalidad de dejar a un lado el verbalismo y dar paso a la conformación de grupos cooperativos en los cuales los alumnos planteen sus inquietudes, busquen alternativas de solución y encuentren sus propias respuestas.
Técnicas de enseñanza de la escritura creativa en el desarrollo de la expresión escrita
Authors: Chasi-Solórzano Byron , Nuñez-Zumba Cristina , Araujo-Chalá María José
Published: January 2025

La escasa aplicación de técnicas de enseñanza de la escritura creativa debido a múltiples factores contribuye a un débil aprendizaje de la expresión escrita. Por ello, es fundamental investigar diversas técnicas que favorezcan el desarrollo de la expresión escrita. El objetivo de esta investigación fue evaluar los efectos de técnicas de enseñanza de la escritura creativa en el desarrollo de la expresión escrita de estudiantes de Educación General Básica (EGB). La aplicación de técnicas innovadoras en la enseñanza requiere que los docentes se comprometan a mejorar e innovar sus prácticas. Para ello, se empleó un enfoque cuantitativo, con diseño cuasiexperimental pre-post test de nivel correlacional. La muestra consistió en 20 estudiantes de 8º de EGB, seleccionados de manera intencional. Se diseñaron clases en las que se aplicaron técnicas de enseñanza de la escritura creativa y se midió el desarrollo de la expresión escrita utilizando una ficha de observación con 5 dimensiones y 20 indicadores. El principal hallazgo es que las técnicas de escritura creativa mejoran significativamente la expresión escrita de los estudiantes. Se concluye que la intervención favoreció aspectos como la ortografía, la secuencia y el orden, la caligrafía, y estimuló la creatividad narrativa permitiendo a los estudiantes presentar ideas innovadoras que promovieron el pensamiento divergente. Además, los estudiantes lograron comunicar ideas con mayor claridad y coherencia, utilizando un registro lingüístico adecuado a la situación comunicativa. La implicación de estos resultados consiente que la incorporación de técnicas de enseñanza innovadoras contribuye a mejorar sustancialmente la expresión escrita.
Development of comprehensive solutions for managing the risks of a pharmaceutical enterprise while ensuring the quality of medicines based on a survey of specialists
Authors: Taube A.A. , Morozov V.A. , Gildeeva G.N.
Published: January 2025

Introduction. The guidelines do not suggest one true path to risk management. Pharmaceutical enterprises develop their own local regulations to ensure compliance with the regulations of the Russian Federation and the EAEU. There are very few studies on how domestic pharmaceutical enterprises solve the problem of introducing a quality risk management system into the enterprise’s quality management system. In this regard, work to study the functioning of the risk management system at Russian pharmaceutical enterprises seems extremely relevant. Objective. Analysis of the activities of the risk management system for the quality of domestic pharmaceutical enterprises to identify systemic errors in its functioning and the subsequent development of methodological approaches to its improvement within the framework of compliance with current good manufacturing practices. Materials and methods. Questionnaire method, descriptive statistics. Results. According to the survey results, the majority of enterprises in the pharmaceutical industry (70.8%) have a system for monitoring and reviewing risks, which indicates a serious approach to risk management. However, almost a third of enterprises (29.2%) do not have such a system, which may indicate possible risks in quality management, as well as the need to implement such systems to ensure more effective control and reduce risks to drug quality. Some domestic enterprises (29.2% of responses) lack systems for monitoring and reviewing risks, which may indicate insufficient control over risks and lack of timely adaptation of the risk management system to changing conditions. The opinion of 52.3% of respondents that the risk management system at their enterprise is formal in nature indicates that the risk assessment system is currently not working effectively enough. The identified problems of the pharmaceutical industry in the field of risk assessment to ensure product quality are formulated: insufficient awareness of employees about some aspects of GMP rules, problems with the distribution of roles and responsibilities when carrying out routine procedures, insufficient theoretical training, inconsistency in the application of standards and procedures, low level of formality in risk assessment procedures, gaps in the understanding and application of risk assessment methods, lack of a systematic approach to monitoring and reviewing risks. Conclusion. Based on the identified problems, the following proposals were developed to improve the quality risk management system at enterprises in the pharmaceutical industry.
Proceso de paz tras el Acuerdo de Belfast: coyuntura actual de los muros de paz en Irlanda del Norte
Authors: Delgado Castresana Mireia
Published: January 2025

La construcción de muros de paz en Irlanda del Norte entre los vecindarios colindantes de católicos y protestantes, focode conflicto, aumentó tras el Acuerdo de Belfast (1998), que sentaba las bases para el inicio de un proceso de paz enla región del Úlster. Estas infraestructuras funcionan como líneas divisorias y segregadoras de los grupos implicados y,simultáneamente, han tenido un papel central en el mantenimiento de la paz. A través del método etnográfico y de laprofundización en otras fuentes como los proyectos Belfast Interface Project (2017) y Public attitudes to Peace Walls (2020),se analiza la evolución de la presencia de las líneas de paz en Irlanda del Norte desde el Acuerdo, y las percepciones dela población que vive próxima a estas fronteras urbanas.
Uncertain Histories: The Archive of Sovereignty in Ottoman Tunis
Authors: Ismail Youssef Ben
Published: January 2025

ABSTRACT: This article examines the French-Ottoman imperial dispute over the sovereign status of nineteenth-century Tunis as a historiographic confrontation. It explores the repercussions of this dispute on our ability to write the history of Ottoman Tunisia and, more broadly, the history of the Ottoman Maghrib. The rivalry between France and the Ottoman Empire produced imperial historiographies that relied on dissonant archives presenting precolonial Tunis as opposite ideal-types, neither of which accounted for the nuances of Tunis's relationship to the Ottoman Empire. The binary view of Tunisian statehood, presented in and enacted through these archives and historiographies, oppose imperial sovereignty and provincial autonomy in a way that became characteristic of international law in the second half of the nineteenth century. This, in turn, contributed to the invisibilization of a set of government institutions, imperial practices, and conceptual repertoires that register a rich tradition of autonomous rule in the Maghribī provinces of the Ottoman Empire.
Spilling Pig Blood in the Muslim Cemetery: The Effort to Expel a Dragoman in Early-Modern Ottoman Istanbul
Authors: Demir Beyza Topuz
Published: January 2025

ABSTRACT: Istanbul court registers preserve an absorbing case from the early eighteenth century: the inhabitants of five neighborhoods lined up against Anton, the dragoman for the British embassy in Istanbul to expel him from his neighborhood. He was accused of opening a pig slaughterhouse and spilling pig blood into the Muslim graveyard. Additionally, he was accused of running an illegal tavern out of his home. Although the accusations were adjudicated according to normal legal procedure, the plaintiffs were not satisfied and entreated the sultan again for his expulsion. This article uses the lawsuits filed against Anton and the insistent nature of the plaintiffs to discuss early modern Ottoman urbanity from the perspective of the neighborhood, law and legality, inter-communal dynamics, and the importance of social status and patronage relations. In doing so, it endeavors to reveal the daily experiences of common people in the context of early modern Istanbul.
Building inclusive classrooms for students with intellectual disabilities
Authors: Suraj Singh
Published: January 2025

In the recent past there is a dramatic progress towards access to education with the Right to Education Act (RTE 2010) in India. The Government of India (GoI) could progressively succeed in achieving high enrollment of students in schools across India this is followed with the provision of midday meals, clean toilets, drinking water facility and various other schemes. The grappling issue is the quality in basic education still remains as a dream. Older students from rural government schools of grade Vth to VIIth still fail to read simple sentence in English or perform a three digit division sum in Mathematics (Annual Status of Education Report - ASER 2016). Inclusive education is arduous for students with Intellectual Disabilities (ID) who have gross challenges in learning the mainstream school curriculum. To overcome the barriers of learning, technical strategies of inclusive education should be practiced in inclusive classrooms. The present paper focuses on essential elements of inclusive classroom for students with ID which includes individualized education program, functional curriculum, assistive technology, curricular modifications, and accommodations.
MENGENAL SISI LAIN POHON MAYANG BAGI KEHIDUPAN MANUSIA
Authors: Kaihena Martha , Nusaly Windy Natalia , Patty Kristi Lenci , Salamena Fuadiska , Manurung Brian Saputra
Published: January 2025

The community service activity with the title "Knowing the Other Side of Mayang Tree for Human Life" is a form of concern for academics in the field of Biology for the spread of society and the development of home industry products that have an impact on improving the health and economy of the community. The transfer of information in the form of processing techniques, ways of utilisation, manufacturing procedures, and marketing techniques is carried out to educate the community in order to increase knowledge about the products and its biological processes. Scientifically, in the procedure of utilisation and processing of palm fruit (mayang), there are many science studies found in everyday life. In addition, indirectly, community students as recipients of information can apply it and become home industry producers. This is very helpful for the community in the utilisation of local wisdom in the area considering kolang kaling is a by-product of palm fruit (mayang) processing.
PELATIHAN PEMBUATAN KERIPIK IKAN GABUS (Channa striata) DI KAMPUNG YOBOI, SENTANI, JAYAPURA
Authors: Mishbach Imam , Ohee Henderite L. , Runtuboi Dirk Y. P. , Gea Liyatin , Tuhumena Lolita
Published: January 2025

The Wali Nibhi Reading House Group, also known as the Yoboi Reading House, was established in November 2019 in Yoboi Village, Sentani, Papua, with a focus on literacy improvement and women's empowerment. The group is predominantly composed of women, making it well-suited to develop skills in producing snakehead fish chips. However, they still face challenges in terms of skills and facilities. The existing skills are not yet sufficient to process fish into value-added products. The community's high dependence on the fisheries sector makes the local economy vulnerable to fluctuations in catch and environmental impacts. Training on processing snakehead fish into low-calorie chips through baking could address these issues. The method used is community-based training. Training in the production of fish stick chips and atom crackers has provided the community with new knowledge and skills. This program is crucial for local economic empowerment, teaching processing techniques and entrepreneurial skills that can increase income and well-being. The training utilizes local natural resources and strengthens the community's self-reliance and competitiveness in a broader market.
Osteopontin and Its Clinical Correlation to Type 1 Cardiorenal Syndrome: A Literature Review
Authors: Welliam Yongki , Wungu Citrawati Dyah Kencono , Susilo Hendri
Published: January 2025

Cardiorenal syndrome (CRS) is a spectrum of disorders involving both the heart and the kidneys, either acutely or chronically, in one organ that can lead to dysfunction in the other. Type 1 CRS, the most common CRS, is when acute heart dysfunction impacts acute kidney dysfunction, commonly known as acute kidney injury. Comorbidities involving these two significant organs contribute to a high patient mortality rate that requires a new potential diagnostic method. Biomarkers are one of the diagnostic modalities widely used in various diseases. Osteopontin (OPN) is a phosphorylated glycoprotein found primarily in bones and teeth that regulates mineralization. Osteopontin is known to be involved in describing various pathological changes in the body, including cardiovascular diseases. This review aims to evaluate the clinical correlation of OPN level changes with the occurrence of Type 1 CRS. The results indicate that OPN also plays a role in detecting the progression of cardiovascular disease towards renal injury. The imbalance in the function of OPN as a pro-inflammatory and anti-inflammatory agent increases the progression of kidney disease in patients. Further findings suggest that, more specifically, urinary OPN describes renal injury events in type 1 CRS patients.
Analysis of Neutrophil, Leukocyte, Lymphocyte, and NLR Cell Profiles in Patients Diagnosed with Chronic Gastritis Affected by Helicobacter pylori and Non-Helicobacter pylori Infection at Dr. Soetomo Hospital in Surabaya, Indonesia
Authors: Aziz Nahdah Aulia , Wahyunitisari Manik Retno , Susilo Imam
Published: January 2025

Helicobacter pylori (HP) is a prevalent cause of bacterial infections, particularly chronic gastritis in the human body. The diagnosis of gastritis relied on gastric biopsy examination, where inflammation is characterized by an increase in various inflammatory cells, including macrophage, neutrophil, lymphocyte, or plasma cells. Therefore, this research aimed to determine the profiles of neutrophil, leukocyte, lymphocyte, and neutrophil lymphocyte ratio (NLR) in chronic gastritis patients, distinguishing between those with Helicobacter pylori and non-Helicobacter pylori infection at Dr. Soetomo Hospital in Surabaya. This research adopted a retrospective method, using medical records for chronic gastritis patients at Dr. Soetomo Hospital between 2018 and 2022. The variables analyzed included Helicobacter pylori infections and values of neutrophil, leukocyte, lymphocyte, and NLR cells. The obtained data were subjected to analysis using descriptive statistics. The results showed that the majority of participants were females (61.9%), senior high school graduates (52.38%), and aged 45-59 (pre-elderly) (32.14%). In non-Helicobacter pylori group, the average values of neutrophil, leukocyte, lymphocyte, and NLR cells were 62.29 (SD = 12.17), 8.155 (SD = 4.02), 29.165 (SD = 12.31), and 3.68 (SD=4.865), respectively. In conclusion, females showed a propensity for chronic gastritis with Helicobacter pylori. It was observed that non-Helicobacter pylori chronic gastritis tended to have elevated neutrophil and leukocyte values. Meanwhile, Helicobacter pylori-related chronic gastritis tended to show increased lymphocyte and NLR values due to systemic inflammation. Helicobacter pylori was associated with conditions such as iron deficiency anemia, cardiovascular disease, diabetes, thyroid disease, and malnutrition.
Antibiotic Of Choice In Patients With Pyogenic Liver Abscess
Authors: Mukti Ilham Ramadhana , Vidananda I Wayan Bagoes , Rahmaningtyas Ihzani , Hasanovic Ilyas , Tsany Imtiyaz , Suryajana I Wayan , Napitupulu Rudi Pandapotan , Fahimi Mukti
Published: January 2025

Pyogenic liver abscess is a dangerous, life-threatening disease with a high mortality rate that requires accurate diagnosis and treatment. The most common symptoms are upper abdominal pain, hepatomegaly, high fever, nausea, and vomiting. Pyogenic liver abscess occurs due to infection from anaerobic bacteria or aerobic bacteria. in the United States the reported annual incidence is 3.6 cases per 100,000 people. But in Taiwan it is 17.6 per 100,000 people. Pyogenic liver abscess sufferers are dominated by men but currently it affects older people more, with the most cases aged 50 to 60 years. The purpose of this study was to know the choice of antibiotics in patients with pyogenic liver abscess. Empiric antibiotics should be initiated immediately upon suspicion of a pyogenic liver abscess tailored to kill all possible bacteria: Gram-negative cocci, gram-positive cocci, and anaerobes. Antibiotic regimens include amoxicillin-clavulanic acid, third-generation cephalosporins combined with aminoglycosides, or piperacillin/tazobactam. In cases of penicillin allergy or antibiotic resistance, fluoroquinolones or carbapenems may be used.
Evaluating the effectiveness of Thiel embalming solution for preserving cadavers in anatomy and surgical education
Authors: Indrawan I Made Rayo Putra , Margiana Ria
Published: January 2025

Cadavers have played a crucial role in anatomy teaching, owing to their resemblance to the anatomical structures found in living individuals. To optimize the utilization of cadavers, embalming procedures that involve the application of chemical fixative agents are needed. The "soft embalming" approach, which involves various salts as fixating agents, was first developed by Walter Thiel. Although the Thiel solution has demonstrated efficacy in enhancing tissue elasticity, consistency, and color, a study is needed to find the most suitable for embalming with this solution to maximize its utility in the context of anatomy and surgical education. The study results show that the Thiel solution produces the best outcomes for its flexibility, uniformity, and color, which is optimal for anatomical and surgical teaching. The efficacy of Thiel's solution for preserving cadavers for educational intentions is noteworthy for the study of anatomy and surgical procedures. The advantageous characteristics of Thiel embalming include flexibility, consistency, and natural coloring. Nevertheless, it is crucial to consider the restrictions associated with preserving the brain, spinal cord, eye, and musculoskeletal tissues. In conclusion, the utilization of Thiel solution has proven to be an efficient embalming agent for preserving cadavers in the fields of anatomy and surgery education, besides brain, spinal cord, eye, and musculoskeletal systems, should be reconsidered.
Mesial Temporal Lobe Epilepsy as a Common but Elusive Case: A Case Report
Authors: Junior Darren , Wulandari Putu Kintan , Harkitasari Saktivi , Sumardika I Wayan , Sumadewi Komang Trisna
Published: January 2025

Epilepsy is a common neuronal disorder that could include partial or generalized seizures due to abnormal brain electrical activity. A 32-year-old female patient was presented to the emergency room with a chief complaint of seizure. The seizure semiology started with epigastric pain, which then progressed into sudden speech arrest. Afterward, the patient experienced left-sided head movement followed by jerkings on the left hand. The patient then became unconscious and experienced full body rigidity. Physical examinations, vital signs, and laboratory results showed no abnormalities. Diagnostic assessments only showed unspecific signs of diffuse cerebral edema through a CT Scan and an atrophy of the right hippocampus with a slight increase in FLAIR signal intensity and dilatation of the right lateral ventricle pericornu through MRI. The patient was given phenytoin and folic acid twice daily. The presence of right mesial temporal sclerosis served as a possible cause of epilepsy in this patient despite having several obscurities. The patient showed atypical signs of generalized tonic seizure progression, adult-onset seizures, and increased MRI FLAIR signal intensity. More detailed examinations and constant reports of epilepsy cases are highly needed among physicians to provide more specific methods and tools to diagnose, classify, and treat epilepsy in the future.
Implant Failure and Acetabular Protrusion Post Austin Moore Prosthesis: A Case Report
Authors: Suropati Bagus Meurah , Soetojo Bagus Wibowo , Ibrahim Rakha Rahmatullah , Mudjiono Totot
Published: January 2025

Implant failure and acetabular protrusion are significant complications following Austin Moore prosthesis insertion, particularly in elderly patients with hip fractures. Total hip arthroplasty (THA) offers superior outcomes compared to hemiarthroplasty (HA) but comes with its own set of challenges. Understanding the risk factors and implications of these complications is crucial for choosing effective management.  In this article, we report a 76-year-old woman who presented with severe left hip pain post-fall, eight years after HA with an Austin Moore prosthesis due to a trochanter fracture. The patient was able to walk with a walker before the fall. Physical examination revealed tenderness and limited range of motion. Radiographic imaging confirmed acetabular protrusion and AMP neck fracture. Conversion to THA using a hybrid system was performed successfully, with the patient exhibiting no post-operative complications. This case report showed that implant failure and acetabular protrusion pose complex challenges, exacerbated by patient demographics, implant design, and bone quality. THA emerges as a preferred option due to its superior outcomes, although conversion from HA is associated with increased risks. Early diagnosis and intervention, as well as a multidisciplinary approach and careful consideration of patient-specific factors, are crucial for optimizing patient outcomes and quality of life.
Impact of Obesity With Chronic Hypertension In Pregnancy Age 35 Years
Authors: Triayuningsasi Nila , Sa’diyah Halimatus , Yulianingsih Hera
Published: January 2025

Background: The incidence of pregnancy with obesity in Indonesia reaches 21.8%. This can be more serious, if the pregnant woman is too old (≥ 35 years) then there will be more complications for the mother and fetus. Method: data collection by interviews and field observations. This case study was written based on objective documentation, analysis, and management. Results: Based on a case study conducted on two pregnant women aged 36 and 38 weeks, 35 years old with obesity and old age. The impact of obesity found is chronic hypertension which will reduce the supply of oxygen and food from the mother to the baby so that the fetus is diagnosed with suspected Intrauterine Growth Restriction (IUGR) and Low Birth Weight (BBLR). The mother is categorized as level II obese so the fetus's weight does not match the gestational age. To prevent complications for the mother and baby, delivery is carried out by cesarean section (SC). The mother's baby is a High Social Value Baby (HSVB).  Contraception The IUD is inserted directly after delivery. Conclusion: Care provided by midwives is appropriate during pregnancy. So that early detection of risk factors can be minimized to prevent possible complications.
Keywords             : Obesity, Pregnancy, Old age, Chronic Hypertension
Chronic rhinosinusitis unveiling a two decades ethmoid foreign body: a case report
Authors: Trihandoko Feri , Fitria Waffi Nur Aini
Published: January 2025

We report a case of a 50-year-old female who presented with rhinosinusitis-like symptoms, which she had been experiencing intermittently for over two decades. Her medical history revealed a nasal surgery performed approximately 22 years ago, after which she continued to experience unresolved symptoms despite multiple treatments. A Computed Tomography (CT) scan of the paranasal sinuses revealed findings with ethmoiditis, prompting the decision for endoscopic sinus surgery to address the underlying pathology. During surgery, there was a 3 cm gauze discovered after opening the posterior ethmoid sinus. We highlight an unexpected foreign body inside the ethmoid sinus based on an unidentified picture from the CT scan, which we accidentally discovered during endoscopic surgery. This case underscores the importance of considering a retained foreign body as a potential cause of chronic rhinosinusitis, even many years after the initial surgical intervention. The unexpected identification of the gauze, which was not clearly depicted in the preoperative CT scan, highlights the challenges in diagnosing retained foreign bodies within the complex anatomy of the sinuses. The report discusses the clinical presentation, diagnostic challenges, and management of this unusual case, contributing valuable insights to the literature on chronic rhinosinusitis and retained foreign bodies in the sinonasal region.
Fábulas para la empatía animal. Desde La Fontaine hasta Julián Chave y Castilla
Authors: Rodríguez García Miguel
Published: January 2025

El objetivo de este trabajo consiste en llevar a cabo un análisis y una tentativa de clasificación teórica de algunas fábulas (principalmente, españolas) de los siglos XVIII y XIX en las que pueden ser percibidas actitudes afectivas hacia ciertos animales no humanos, lecciones sobre su protección y cuidado, o testimonios y denuncias por el abuso y la ingratitud de los seres humanos. Para ello partiremos de la perspectiva de los estudios de animales, cuyos investigadores, por norma general, no han apreciado demasiado el género fabulístico. Pese al antropocentrismo reinante en la época y en este género literario, demostraremos que algunas fábulas, tanto antiguas como modernas, revelan elementos útiles para una crítica literaria acorde con los postulados de los estudios de animales. Estas fábulas —poco abundantes en número, por más que su presencia pueda atestiguarse en la producción de distintos autores— poseen relevancia para los estudios de animales y deberán seguir siendo localizadas y comentadas en investigaciones futuras.
The Purposes of Education: A Citizen Perspective Beyond Political Elites
Authors: Henrekson Ebba , Andersson Fredrik O. , Willems Jurgen
Published: January 2025

Education has long been an area of political debate in the United States, with politicians and policymakers advocating for distinct societal and/or individual purposes of K–12 education. In this article, we examine the public opinion on the purpose of education, and we explore whether this political divide on the purpose of education is also represented in the broad public opinion. For a sample 19,032 U.S. respondents, we test whether citizens’ partisanship corresponds with their opinions on seven educational purposes. We observe that the public opinion represents a multifunctional view on education and that some but rather small differences relate to partisanship. We frame these findings in the existing literature and postulate avenues for further research.
Inside out: New root endophytic Penicillium and Talaromyces species isolated from Cattleya orchids (Orchidaceae) in Brazil
Authors: Condé T.O. , Ramos D.O. , Nogueira P.T.S. , Pereira O.L.
Published: January 2025

The Orchidaceae family comprises a highly diverse group of flowering plants. The genus Cattleya is restricted to the Neotropics, with approximately 80 % of the species present in Brazil occurring in epiphytic, rupicolous, and terrestrial habitats. During surveys that aimed to investigate root fungal endophytes of two native orchids, C. locatellii and C. violacea, a total of 10 endophytic isolates were identified as belonging to Eurotiales. A polyphasic approach was applied for the identification and characterization of the cultured species, combining morphological and molecular data. Phylogenetic analyses were performed using the internal transcribed spacers (ITS) of the rDNA, beta-tubulin (BenA), calmodulin (CaM), and RNA polymerase second-largest subunit (RPB2) sequences. Two new endophytic species were identified and described from roots of C. locatellii, namely Penicillium endophyticum sp. nov. (section Aspergilloides), and Talaromyces cattleyae sp. nov. (section Purpurei). In addition, P. yuyongnianii (section Lanata-Divaricata), T. amestolkiae, and T. atkinsoniae (section Talaromyces) were reported as endophytes from the genus Cattleya.
Konvention über die Rechte von Menschen mit Behinderungen der Vereinten Nationen (UNO-BRK) – Umsetzungsstand und Reformbedarf in der schweizerischen Psychiatrie [United Nations Convention on the Rights of People with Disabilities (UN CRPD) - Implementation status and need for reform in Swiss psychiatry]
Authors: Richter Dirk , Ambord Nora , Andersson Sabine Rühle , Burr Christian , Hasler Melina , Hegedüs Anna , Wolfensberger Peter
Published: January 2025

Die Umsetzung der UN-Behindertenrechtskonvention (UNO-BRK) stellt für die Schweiz eine bedeutendeHerausforderung dar. Trotz der grundlegenden Verpflichtungen zur Gleichbehandlung aller Menschenmit und ohne Behinderungen bleibt die praktische Anwendung lückenhaft. In diesem Arbeitspapierwird die Umsetzung der bestehenden Rechtslage analysiert, um Reformbedarf und notwendigeHandlungsperspektiven für die psychiatrische Versorgung der Schweiz zu identifizieren.Unsere Analyse zeigt, dass die schweizerische Psychiatrie noch einen langen Weg vor sich hat, um dieZiele der UNO-BRK vollständig zu erreichen. Wichtige Aspekte sind die Harmonisierung dergesetzlichen Grundlagen, die Schaffung von inklusiven und nicht-stigmatisierenden Begriffen sowiedie Förderung der Teilhabe in verschiedenen Lebensbereichen. Eine konzertierte Anstrengung aufallen staatlichen Ebenen, gepaart mit einer fundierten Datenerhebung und der Einbindung vonBetroffenen in die Entscheidungsprozesse, sind unerlässlich für eine nachhaltige Verbesserung derLebensqualität von Menschen mit Behinderungen in der Schweiz.SummaryThe implementation of the UN Convention on the Rights of Persons with Disabilities (CRPD) representsa significant challenge for Swiss psychiatry. Despite the fundamental obligations to treat all peoplewith and without disabilities equally, practical application remains patchy. This working paperanalyses the implementation of the existing legal situation in order to identify the need for reformand the necessary perspectives for action.Our analysis shows that Swiss psychiatry still has a long way to go to fully achieve the goals of the UNCRPD. Important aspects are the harmonisation of the legal basis, the creation of inclusive and nonstigmatising terms and the promotion of participation in various areas of life. A concerted effort at all levels of government, coupled with sound data collection and the involvement of those affected indecision-making processes, are essential for a sustainable improvement in the quality of life of peoplewith disabilities in Switzerland.
Exploring the Impact of Artificial Intelligence-Mediated Communication on Bias and Information Loss in Non-academic and Academic Writing Contexts
Authors: Towne Bryce Petofi
Published: January 2025

Artificial Intelligence-Mediated Communication (AI-MC) has significantly transformed text production and perception, yet its effects on bias and information loss across various writing contexts remain underexplored. To address this, we conducted two studies involving non-academic texts (N = 572) and academic texts (N = 420). Participants were randomly assigned to read either original texts or texts refined by one of three AI models: ChatGPT 4.0, Claude 3 Opus, or Gemini Advanced. We assessed bias perception using a 5-point Likert scale and measured information loss through multiple-choice comprehension questions. Using Mann-Whitney U tests, we compared differences between groups. In non-academic contexts, ChatGPT 4.0 significantly reduced perceived emotional bias compared to original texts (p < .01), whereas Gemini Advanced slightly increased bias in specific emotional scenarios (p < .05). No AI models led to significant differences in information loss (p > .05). In academic contexts, neither ChatGPT 4.0 nor Claude 3 Opus significantly impacted bias perception or information loss (p > .05). These findings suggest that while certain large language models can mitigate perceived bias in non-academic writing, they do not markedly influence information loss in either non-academic or academic texts. Consequently, the integration of AI-refined texts in academic publishing should proceed with caution, and further research is warranted to explore AI-MC's effects across diverse linguistic and cultural environments.
Deep Brain Sound Stimulation for Depression: Precision Auditory Stimulation
Authors: Dogan Ugur
Published: January 2025

Background: Depression is a prevalent and debilitating mental health disorder, affecting over 280 million people globally and leading to significant disability. Traditional treatments like pharmacotherapy and behavioral interventions, while effective, are often limited by side effects and accessibility issues.Objective: This study assesses the effectiveness and safety of Deep Brain Sound Stimulation (DBSS), a novel non-invasive auditory therapy, based on user-reported outcomes from individuals with depression.Methods: We analyzed feedback from 242 users who completed DBSS therapy via the Vital Tones mobile application on the Apple App Store. Additionally, 12 participants provided detailed responses through in-app surveys evaluating symptom improvements in mood, cognitive function, and emotional regulation. Descriptive statistics were used to determine median effectiveness and satisfaction rates.Results: The therapy demonstrated a high user satisfaction rate of 99.59%, with a minimal refund rate of 0.41%. Survey respondents reported a median symptom improvement of 48% (95% CI: 42.60%–52.40%). DBSS was well-tolerated, with only minor side effects reported in a small number of sessions.Conclusion: Preliminary findings indicate that DBSS is a promising non-invasive treatment for depression, offering significant symptom improvement and high user satisfaction. However, the observational nature of the study, small survey sample, and reliance on self-reported data suggest that further controlled research is necessary to validate these results and establish DBSS's efficacy and safety.
Bureaucracy under Authoritarian Rule: Autonomy and Resilience of Administrative Institutions in Divided Times
Authors: Yesilkagit Kutsal
Published: January 2025

In order to successfully establish their new rule, authoritarian regimes that seize power through democratic elections need to find some modus of operation with the bureaucracy. How will authoritarian regimes approach the matter of securing the civil service to their cause and how will the bureaucracy respond to an authoritarian seizure of power? These questions are central in this paper that explores the strategies of authoritarian regimes after they have come to power in democratic systems. The theoretical point of reference are theories of political administrative relationships, but our explorative case study, the Nazi’s civil service politics after they seized power in Weimar Germany in 1933, also demonstrate the need to delve into adjacent theories of autonomy, civil service systems, and bureaucratic politics and competition. The paper’s main goal is to present six propositions to the problem that can guide further research on the issue of bureaucratic resilience under authoritarian rule.
The Electoral Politics of Immigration and Crime
Authors: Alizade Jeyhun
Published: January 2025

Concern that immigration worsens crime problems is prevalent across Western publics. How does it shape electoral politics? Prior research asserted a growing left-right divide in immigration attitudes and voting behavior due to educational realignment. In contrast, I argue that leftist voters are more conservative on immigrant crime than leftist parties, which can drive highly-educated progressives (so-called `cosmopolitans') to right-wing parties. I demonstrate this voter-party mismatch using survey data from 14 Western European countries linked with expert ratings of party positions. A panel survey from Germany further shows that concern about immigrant crime increases vote intention for the center right among voters of the Greens – the party of leftist cosmopolitans. A conjoint experiment among German voters replicates this defection effect and shows that it persists even if the center right stigmatizes immigrants or adopts conservative socio-cultural issue positions. Repercussions of immigration can in fact drive leftist cosmopolitans to the right.
CTS (Cosmic Theory of Structure): A Validated Universal Model Integrating Gravity and Quantum Physics
Authors: OZTURKLER Hazar Umutay
Published: January 2025

The Combined Theoretical Signal (CTS) model, with a 90% or higher validity rate, stands as the first validated universal model integrating gravity and quantum physics. This manuscript presents the final validation and enhancement of the CTS model using recent pulsar-sourced gravitational wave data (J2322+2057, J2234+0611, J2043+1711, and J2317+1439) and strain data from GW150914, GW151226, GW190521, and GW200105. Our findings demonstrate a significant alignment between theoretical predictions and observational data, positioning CTS as a groundbreaking framework with profound implications for theoretical physics and cosmology. The CTS model not only bridges the gap between gravity and quantum mechanics but also offers a new perspective on the formation of massive black holes, the Quantum Cosmic Fabric (QCF), and the structure of the universe as an interconnected hierarchical tree of universes.
Active without thinking? Distinguishing between automatic responses as predictors of physical activity
Authors: Terashima Maika , Rebar Amanda L. , Naredi Himanshi , Khafi Naomi , Maltagliati Silvio , de Chanaleilles Margaux , Zenko Zachary , Cheval Boris , Gardner Benjamin
Published: January 2025

Background. Regular physical activity (PA) improves both physical and mental health, yet most people are insufficiently active. Identifying modifiable determinants of PA will aid development of effective PA promotion interventions. It is well recognised that PA is at least partly regulated by automatic processes, which capture simple associations that trigger behaviour without conscious thought. Yet, few attempts have been made to identify which specific automatic processes are most influential, nor on the role of specific automatic processes on different forms of PA. This study explored relationships between three automaticity variables – i.e., automatic evaluations, approach-avoidance tendencies, and habit strength – and engagement in sport, leisure-based and total PA.Method. A cross-sectional survey design was used. A sample of 226 individuals (mean age 23.70 years) self-reported engagement in sport-based PA, leisure-time PA, and active travel. They also reported habit strength for sport and for leisure-time activity, and completed response-time tasks capturing automatic evaluations and approach tendencies towards PA. Correlation analyses were used to assess the magnitude of relationships between all variables, and regression analyses to model associations between automaticity variables and sport and leisure-time PA, respectively.Results. Automatic evaluations, approach tendencies, and sport habit strength all independently and positively predicted sport-based PA and total PA engagement. However, leisure-time PA was predicted only by leisure activity habit strength, not automatic evaluations or approach-avoidance. Leisure-time habit strength was the only predictor of a composite PA engagement measure combining total time in sport, leisure-time activity and active travel.Discussion. Our findings warrant replication using more rigorous methods. Nonetheless, they suggest that promoting positive automatic evaluations, approach tendencies and habit strength could encourage engagement in sport-based PA, whereas interventions to increase PA more generally might fruitfully emphasis PA habit formation.