bluuebunny/crossref_metadata_2025 huggingface dataset:
Volumetric Fetal Flow Imaging with Magnetic Resonance Imaging
Authors: Goolaub Datta Singh , Xu Jiawei , Schrauben Eric , Marini Davide , Kingdom John , Sled John , Seed Mike , Macgowan Chris
Published: August 2021

Fetal development relies on a complex circulatory
network and accurately assessing the flow distribution is important for
understanding pathologies and potential therapies. In this paper, we
demonstrate a method for volumetric multidimensional imaging of fetal flow with
magnetic resonance imaging (MRI). Fetal application of MRI faces several
challenges such as small vascular structures, unpredictable motion, and lack of
traditional cardiac gating methods. Here, orthogonal multislice stacks are
acquired with accelerated multidimensional radial phase contrast (PC) MRI. Each
slice is reconstructed into flow sensitive time-series images (CINEs) with
retrospective intraslice motion correction and image-based fetal cardiac
gating. CINEs are then combined into a dynamic 3D volume using slice-to-volume
reconstruction (SVR) while accounting for interslice spatiotemporal
coregistration. Validation of the technique is demonstrated in adult volunteers
by comparing mean flows from SVR with 4D radial PCMRI with bias and limits of
agreement being -1.1 ml/s and [-12.5 10.2] ml/s. Feasibility is demonstrated in
late gestation fetuses by comparing SVR with 2D Cartesian PCMRI with bias and
limits of agreement being -0.9 ml/min/kg and [-39.7 37.8] ml/min/kg for mean
flows. With SVR, we also demonstrate complex flow pathways (such as parallel
flow streams in the proximal inferior vena cava, preferential shunting of blood
from the ductus venosus into the left side of the heart, and blood returning
from the brain leaving the heart through the main pulmonary artery) for the
first time in human fetal circulation. This method allows for comprehensive
evaluation of the fetal circulation and enables future studies of fetal
physiology.
Cytotoxic and Genotoxic Effects of Methanol Extracts of Some Gypsophila L. Species
Authors: Korkmaz Ferhan , Tuna Gülören Özgün , Erdir Meltem , Ataşlar Ebru
Published: August 2021

In this study, the cytotoxic and genotoxic effects of Gypsophila perfoliata L. var. perfoliata, Gypsophila perfoliata L. var. araratica Kit Tan, Gypsophila pilosa Hudson and Gypsophila osmangaziensis Ataşlar & Ocak plant extracts have been examined by using Allium Test method. Methanol extracts of plants have been prepared in 4 different concentrations (0.625 mg/ml, 1.250 mg/ml, 2.500 mg/ml and 5.000 mg/ml). After the onion roots were treated at these concentrations of plant extracts for 24 hours and 48 hours, mitosis preparations were prepared from these root tips. With the data being obtained by evaluating the preparations, mitotic index (%) and  chromosome aberration (%) values have been calculated. Distilled water has been used as control group. It was found out that mitotic index and chromosome aberration values of all species showed significant differences compared to control group in the extract concentration range of 1.250–5.000 mg/ml. It has been determined that the most widely observed chromosome aberrations were disturbed metaphase, sticky metaphase, c-metaphase, disturbed anaphase and anaphase bridge.
How Definitive is Fourth Amendment Textualism?
Authors: Caminker Evan
Published: August 2021

Professor Jeffrey Bellin’s excellent article advances a comprehensive and straightforward textual approach to determining what policing activities constitute “searches” triggering the protections of the Fourth Amendment. Bellin’s thesis is that a text-based approach to interpreting the Amendment is superior to the Supreme Court’s current approach, which ever since Katz v. United States has defined “search” primarily by reference to a non-textual “reasonable expectation of privacy” standard. After soundly criticizing the ungrounded and highly subjective nature of the Katz test, Bellin declares that the Court should instead simply follow where the text leads: the Amendment protects people from a search, meaning an “examination of an object or space to uncover information” of their own “persons, houses, papers, and effects.” No more, no less. Such a textual approach generates new doctrinal rules that would replicate Katz’s outcomes in many respects and provide either more or less protection in others.
El Aula Virtual como Estrategia Didáctica en un Mundo Transformado por el Covid-19
Authors: Arellano Landeros Jesus
Published: August 2021

Este artículo describe una propuesta constructiva acerca del nuevo rumbo que están tomando las Instituciones de Educación Superior (IES), para abatir el efecto del confinamiento en nuestro país producido por la pandemia a nivel mundial, donde la búsqueda de reestructurar y transformar los procesos de enseñanza aprendizaje en  la ENSVM sede Nezahualcóyotl, el propósito es continuar laborando en la impartición de catedra, ante el riesgo de la integridad de salud de todos los estudiantes, personal docente y administrativo, por medio del uso del Aula Virtual como medio de comunicación asertiva, sabemos que el conflicto de contagio debido a este fenómeno es de consecuencias graves y consideramos como única alternativa el uso del aula virtual que por medio de las Tecnologías de la Información y Comunicación (TIC), es la solución más viable en primer momento para preservar la salud y  favorecer la formación continua de los estudiantes con estrategias didácticas que van desde la interacción de docentes y alumnos, hasta culminar con la entrega, recepción, revisión y retroalimentación de tareas como se venía haciendo antes de esta eventualidad, y  continuar trabajando con responsabilidad, siendo inclusivos  y empáticos en todo momento además como principales actores educativos teniendo que hacer frente a este nuevo reto de transformación en la forma de impartir clases, a distancia, con el propósito de abatir el efecto del COVID-19[1], de manera eficaz con el fin de  sustituir la educación presencial con el nuevo modelo de educación a distancia como estrategia y resultado de una investigación descriptiva y cuantitativa en la que se fundamenta teóricamente la habilidad docente, y el proceso seleccionado para solucionar problemas de manera inmediata en caso de estudio en la ENSVM sede Netzahualcóyotl, donde se implementó el uso de la plataforma virtual.

 

2 Virus que causa una enfermedad respiratoria llamada enfermedad por coronavirus de 2019 (COVID-19). El SARS-CoV-2 es un virus de la gran familia de los coronavirus, un tipo de virus que infecta a seres humanos y algunos animales.
La escritura digital: ¿Un reto posible de lograr en niños que inician el proceso de alfabetización?
Authors: Colunga Jiménez Carolina , Martínez Victoriano Jorge Luis , Vidal Pulido José Luis
Published: August 2021

A lo largo del tiempo la concepción de escritura se ha ido transformado, originalmente se concebía como una habilidad mecánica que únicamente requería la memorización del sonido de las letras y la ejercitación de las reglas convencionales de la gramática. Hoy en día el concepto va mucho más allá y destaca la función comunicativa que tiene el lenguaje escrito, haciendo énfasis en las prácticas sociales del lenguaje. Los programas de estudio de educación primaria contemplan estos propósitos y plantean actividades que intentan favorecer este enfoque; sin embargo, aún falta mucho por hacer para considerar que la escuela está cumpliendo su función protagónica en la formación de escritores versátiles, creativos y competentes. Actualmente, la educación formal tiene un fuerte soporte en la utilización del lenguaje escrito, para su aprendizaje se emplean distintas estrategias con la intención de apoyar la alfabetización inicial. Desafortunadamente, muchas de ellas buscan promover las producciones textuales de los niños anclándose en una vieja tradición que considera únicamente la escritura con papel y lápiz, olvidando las demandas sociales que emergen en contextos extra-áulicos, generadas por los cambios sociales y económicos de principios de siglo. Este trabajo apuesta por el uso de las Tecnologías de la Información y Comunicación  (TIC) en tareas de alfabetización, recoge datos sobre la forma lenta y paulatina en la que un grupo de primer grado de educación primaria evolucionaba en torno a sus niveles de escritura empleando entornos analógicos y analiza la rápida movilización que vivieron los pequeños cuando se incorporaron entornos digitales a las actividades escolares.
Experiencias y sentires en torno a la pandemia del virus COVID-19, la perspectiva de los estudiantes universitarios
Authors: López-Botello Felisa Yaerim , Mendieta-Ramírez Araceli , Alejandro-García Saúl
Published: August 2021

Este artículo constituye un ejercicio de reflexión sobre los efectos de la educación a distancia en estudiantes de Instituciones de Educación Superior (IES), ante la emergencia sanitaria provocada por la pandemia del virus COVID-19, que ha tenido efectos en los ámbitos social, económico, familiar y personal.

Los ajustes y adaptaciones a los recursos digitales han significado diversos grados de dificultad, en función de su combinación o cruce con las brechas regionales, económicas, digitales, desigualdades y desventajas que se podrían seguir desagregando, como la alfabetización digital, tanto para docentes y estudiantes. Estas miradas a las desigualdades ponen al descubierto las realidades locales, familiares y personales de los estudiantes conectados y desconectados de la educación digital.

En este escenario de tránsito repentino de la educación presencial a la educación digital, la presente investigación se realizó con el objetivo de explorar las experiencias y sentires de los estudiantes de dos universidades públicas, para ampliar la información sobre las formas en que se adaptaron durante el periodo de confinamiento a las condiciones de inmovilidad y educación a distancia, así como los recursos digitales que utilizaron. 

Se inició con una genealogía sobre las bases y principios en los que se funda las transformaciones que problematizan el papel de la universidad pública latinoamericana. Seguidamente, se reflexionó sobre el papel que han tomado la Universidad Pedagógica Nacional (UPN), 151 Toluca y la Universidad Autónoma del Estado de México (UAEMex), en relación con la emergencia, a través de un diagnóstico socioeducativo. La importancia de conocer las experiencias de estudiantes permitió integrar la preocupación por el estado anímico al tema de las desigualdades digitales y entornos locales. El estudio identificó que los estudiantes de la Universidad Autónoma de México presentaron ciertos temores relacionados con problemas de conectividad, salud y economía. Mientras tanto, los estudiantes de la UPN mostraron preocupaciones en torno a la economía familiar, la salud y la conectividad, pero a diferencia de los primeros, los estudiantes Upnianos son más vulnerables por el contexto geográfico-social en donde viven.

También el estudio permitió la reflexión de que se requiere flexibilizar el currículo, como mencionan los expertos, uso de las plataformas en función de las necesidades de cada asignatura. Se insiste en que la educación tiene que ser flexible y adaptarse a las necesidades y características de los estudiantes y de los diversos contextos sociales y culturales. Esto exige, transitar desde una pedagogía de la homogeneidad hacia una pedagogía de la diversidad, aprovechando ésta como una oportunidad para enriquecer los procesos de enseñanza, aprendizaje y optimizar el desarrollo personal y social.
Penerapan Pembelajaran Matematika Berbasis HOTS oleh Mahasiswa dalam Perkuliahan Pengajaran Mikro
Authors: Sulistyani Niluh , Silvia Silvia , Alfreda Lucia Endy Gracia
Published: August 2021

Penelitian ini bertujuan untuk menganalisis desain pembelajaran matematika berbasis HOTS serta menganalisis tantangan mahasiswa dalam mengembangkan pembelajaran matematika berbasis HOTS dalam konteks perkuliahan Pengajaran Mikro. Subjek penelitian ini adalah 16 mahasiswa yang mengikuti perkuliahan Pengajaran Mikro kelas B. Teknik pengumpulan data yang digunakan adalah penyebaran angket, observasi, dan wawancara. Data hasil penelitian dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa desain pembelajaran matematika berbasis HOTS terlihat pada dalam kegiatan pendahuluan, inti, dan penutup pembelajaran. Pada kegiatan pendahuluan, penerapan HOTS terlihat dalam kegiatan apersepsi dan motivasi. Penerapan HOTS pada inti pembelajaran dilakukan dengan memberikan soal atau masalah HOTS, menerapkan pembelajaran berbasis masalah (problem-based), menggunakan alat peraga, gambar, dan media lainnya untuk menemukan konsep, dan melakukan tanya jawab untuk merangsang mahasiswa berpikir kritis. Pada kegiatan penutup, aktivitas HOTS terlihat dalam menarik kesimpulan dan penugasan dengan pemberian proyek. Namun, dalam persiapan dan pelaksanaan pembelajaran, mahasiswa mengalami beberapa tantangan dan kesulitan, diantaranya menemukan ide pembelajaran, membuat masalah dengan level HOTS, tidak mudah membuat mahasiswa memahami materi matematika, memerlukan waktu yang lebih lama dan perlunya pemahaman mendalam mengenai pembelajaran berbasis HOTS. Dengan mengetahui kesulitan-kesulitan yang dialami mahasiswa dalam mendesain pembelajaran berbasis HOTS ini dapat membantu dosen menentukan metode pembelajaran yang tepat untuk meminimalisir kesulitan tersebut.
PHYSICAL QUALITY AND PRODUCTIVITY OF COCOA BEAN (Theobroma cacao L.)
BASED ON CANOPY POSITION AND PLANT AGE
Authors: Sarawa  , Halim  , Dirvamena Boer  , Asriningsih
Published: August 2021

The research aimed to study the cocoa bean quality and productivity based on their position on canopy and different plant ages. This has been conducted at cocoa farming area at Wonggeduku Subdistrict, Konawe Regency, Southeast Sulawesi Province. These treatments were arranged based on the nested design in which the pod position on the canopy i.e. on main stem, primary and secondary branches, and nested to the plant ages i.e. 8,10, 12, and 14 years old were used. The observed variable were pod length, pod diameter, seed weight, seed number, and dry production per pod. The data gathered were analysed by analysis of variance and the difference between treatments were justified by Duncan’s Multiple Range Test at 95% significant level. To study the relationship between plant ages and pod position on canopy, the regression analysis was applied. Research result showed that there were interaction effect on pod position and ages on all variable observed. The best treatment on the main stem and primary branch at eight year age of the plant was on the length, diameter and weight of pods, seed number, and dry seed production per pod.
KEY WORDS: Cocoa pod, plant age, pod position, production, quality
Pengaruh Model Pembelajaran Problem Based Learning (PBL) Terhadap Kemampuan Berpikir Kritis Matematis Siswa pada Materi Sistem Persamaan Linear Dua Variabel
Authors: Nufus Hayatun , Herizal Herizal , Sahputri Linda Dewi
Published: August 2021

Matematika merupakan pelajaran wajib yang sudah diajarkan semenjak dasar hingga menengah, matematika dapat melatih dan mengembangkan kemampuan berpikir siswa. Namun, banyak siswa yang menganggap matematika adalah mata pelajaran yang sulit dipahami. Siswa cenderung menghindari bahkan takut untuk belajar matematika, sehingga menyebabkan rendahnya kemampuan berpikir kritis matematis siswa. Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Problem Based Learning (PBL) terhadap kemampuan berpikir kritis matematis siswa. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian Quasi Eksperimental Design dan rancangan penelitianThe Non equivalent Postets-Only Control Grup Design.Populasidalampenelitian ini adalah kelas VIII SMP Negeri 4 Dewantara, sementara sampelnya yaitu kelas VIII2dan VIII3dengan teknik pengambilan sampel adalah Purposive Sampling. Adapun Teknik pengumpulandatayangdigunakandalam penelitianini adalah tes kemampuanberpikirkritis matematis siswa. Analisis data yang dilakukan untuk tes kemampuan berpikir kritis matematis menggunakan uji-t karena data berdistribusi normal dan homogen. Dari hasil uji hipotesis didapatkan nilai signifikan 0,001 yang artinya tolak Ho sehingga dapat disimpulkan bahwa dengan menggunakan model pembelajaran Problem Based Learning (PBL) berpengaruh pada kemampuan berpikir kritis matematissiswa.Mathematics is a compulsory subject that has been taught from elementary to middle school, mathematics can train and develop students' thinking skills. However, many students consider mathematics to be a difficult subject to understand. Students tend to avoid and even fear learning mathematics, resulting in low students' mathematical critical thinking skills. This study aims to determine the effect of the Problem Based Learning (PBL) learning model on student's mathematical critical thinking skills. This research uses a quantitative approach with the type of research Quasi Experimental Design and the research design of The Nonequivalent Postets-Only Control Group Design. The population in this study was class VIII SMP Negeri 4 Dewantara, while the sample was class VIII2 and VIII3 with the sampling technique using purposive sampling. The data collection technique used in this study was a test of students' mathematical critical thinking skills. The data analysis conducted for the test of mathematical critical thinking skills used the t-test because the data were normally distributed and homogeneous. From the results of the hypothesis test, it was obtained a significant value of 0.001, which means reject Ho, so it can be concluded that using the Problem Based Learning (PBL) learning model has an effect on students' mathematical critical thinking skills.
Pengaruh Model Pembelajaran Numbered Head Together (NHT) Terhadap Peningkatan Kemampuan Pemahaman Konsep Berbantuan Software
Authors: Nasution Zulaini Masruro
Published: August 2021

Penelitian ini bertujuan untuk mengetahui ada tidaknya pengaruh model pembelajaran Numbered Head Together terhadap kemampuan pemahaman konsep siswa kelas X SMK Teladan Pematangsiantar tahun 2020 sebelum diberi perlakuan (pretes) dan sesudah diberi perlakuan (postes) pada kelas eksperimen. Penelitian ini merupakan penelitian eksperimen semu.Populasi dalam penelitian ini adalah seluruh kelas X SMK Teladan Pematangsiantar yang berjumlah 74 orang.Sedangkan sampel yang digunakan pada penelitian ini berjumlah 37 orang.Sampel penelitian ditentukan dengan teknik simple random sampling.Pengumpulan data dengan menggunakan teskemampuan pemahaman konsep dengan soal uraian berjumlah 5 butir. Data di analisis menggunakan uji normalitas dan ujihi potesis yaitu paired simples t-test .Hasil penelitian menunjukkan bahwa terdapat pengaruh model pembelajaran Numbered Head Together  terhadap kemampuan pemahaman konsep siswa dari uji pretes dan postes yang diberikan pada siswa kelas X SMK Teladan Pematangsiantar. Rata-rata nilai posttest adalah 44,67 lebih tinggi dari nilai pretest 18,56 dan presentase kenaikannya adalah 13%. Adanya perbedaan yang signifikan menunjukkan bahwa pembelajaran menggunakan model pembelajaran Numbered Head Together berpengaruh positif terhadap kemampuan pemahaman konsep siswa.This study aims to determine whether there is influence of the model of learning Numbered Head Together on the ability to understand the concept of class X students of SMK Teladan Pematangsiantar in the 2020 lesson years before being treated (pretested) and after being treated (postes) in the experimental class. This research is a quasi-experimental research. The population in this study is the entire class X students of SMK Teladan Pematangsiantar which amounted to 74 people. While the sample used in this study amounted to 37 people. The sample is determined by simple random sampling technique. Data collection by using concept comprehension comprehension test with 5 item description. Data were analyzed using normality test and hypothesis test that paired simples t-test. The result of the research shows that there is influence of the Numbered Head Together learning model to the students' concept of pretest and post test which is given to the students of grade X students of SMK Teladan Pematangsiantar. The average posttest score is 44.67 higher than the pretest value of 18.56 and the percentage increase is 13%. The existence of significant differences indicate that the learning using the model of learning Numbered Head Together have a positive effect on students' concept of understanding ability.
Development of a recipe for bakery products using new protein raw materials
Authors:   Federal State Autonomous Scientific Institution «Scientific Research Institute of the Bakery Industry», Evdokimova A.S. , Nevskaya E.V. ,   Federal State Autonomous Scientific Institution «Scientific Research Institute of the Bakery Industry», Tyurina O.E. ,   Federal State Autonomous Scientific Institution «Scientific Research Institute of the Bakery Industry»
Published: August 2021

Население испытывает систематический дефицит белка, до 99% жителей недополучают этот необходимый компонент питания [20]. Исследовано влияние нового нетрадиционного высокобелкового сырья: муки из мухи Черная львинка (далее белковая добавка) на микробиологические показатели, гранулометрический состав, белково-протеиназный комплекс пшеничной муки, газообразующую и газоудерживающую способности теста, физико-химические и органолептические показатели качества хлебобулочных изделий. Выявлено, что добавление белковой добавки к массе пшеничной муки первого сорта способствовало снижению количества и качества клейковины по сравнению с контрольным образцом. Установлено, что добавление 20% белковой добавки к массе пшеничной муки первого сорта способствовало снижению в хлебобулочных изделиях удельного объема на 53,6%, пористости - на 3,8% по сравнению хлебобулочными изделиями без добавки. Для оптимизации количества белковой добавки и сухой пшеничной клейковины использовали метод математического моделирования. Установлено, что внесение белковой добавки в количестве 7% к массе муки и сухой пшеничной клейковины в количестве 1% от массы муки позволит получить хлебобулочные изделия по физико-химическим и органолептическим показателям на уровне контрольного образца. Рассчитана пищевая ценность изделий. Установлено, что по сравнению с контрольным образцом содержание белка повысилось на 34%.
ЕКСПОЗИЦІЙНИЙ ПРОСТІР «УКРАЇНСЬКА МОВА» У ЗАКЛАДАХ ЗАГАЛЬНОЇ СЕРЕДНЬОЇ ОСВІТИ
Authors: Горошкіна Олена Миколаївна
Published: August 2021

У доповіді представлено ініціативу Уповноваженого із захисту державної мови, відділу навчання української мови та літератури Інституту педагогіки Національної академії педагогічних наук України та Педагогічного музею України щодо створення у закладах загальної середньої освіти експозиційного простору з вивчення, утвердження і популяризації української мови. Основними завданнями експозиційного простору є виховання в молоді патріотизму, формування активної громадянської позиції, ціннісного ставлення до української мови, історії, культури українського народу, мовної стійкості, стимулювання дослідницької діяльності здобувачів освіти тощо.
Development of lightweight cement slurries for stabilizing producing formation in absorbing wells
Authors:   SOCAR, Mehdiyev K.K. , Ibrahimov Kh.M. ,   "Oil-Gas Scientific Research Project" Institute, Azerbaijan Republic
Published: August 2021

The paper presents the results of laboratory investigations on the development of lightweighted cement compositions for improvement of stabilizing of producing formation, as well as the hermetization of the areas with low frac gradients. To obtain lightweighted cement, few optimum compositions have been specified through experiments adding the agents in various thickness and concentrations into the mixture. The distribution of optimum compositions, the beginning and end of the hermetization, the solidness and density have been defined. The density of cement slurry developed on cement+seawater is 1900 kg/m3, the density of that on the cement+seawater+chamotte+bark+polymer+CaCl2 is 1610 kg/m3, the density of one developed on the cement+seawater+bark+CaCl2+carbonate+Al powder is 1700 kg/m3 and the density of cement slurry on cement+seawater+bark+CaCl2+keramzit comprised 1590 kg/m3.
Intrastratal regimes and reservoir properties of productive horizons in Sangachal-deniz–Duvanny-deniz–Khara-zira adasy fields
Authors:   “28 May” OGPD, SOCAR, Kazimov R.R.
Published: August 2021

The paper reviews the intrastratal regimes and reservoir properties of V, VII and VIII horizons in Sangachal-deniz–Duvanny-deniz–Khara-zira adasy fields. As a result of studies of core samples taken from 1700–5750 m depth, lithological-reservoir characteristics of the rocks have been analyzed, the changing intervals of parameter values shown as well. Therefore, instratal regimes of productive horizons have been analyzed, the dependence of initial formation pressure on hydrostatic and saturation pressures specified. Considering all mentioned above, 3D models of deep structure of SDKhZ (by VII horizon) field have been developed, corresponding vector directions in structural form of studied area defined as well.
PENGARUH DISIPLIN KERJA TERHADAP KINERJA PEGAWAI DI PT BRIDGESTONE PONDOK BANDAR JAMBU KABUPATEN SIMALUNGUN
Authors:   Politeknik Bisnis Indonesia, Simarmata Hengki Mangiring Parulian , Saragih Doris Yolanda ,   Politeknik Bisnis Indonesia, Panjaitan Nora Januarti ,   Politeknik Bisnis Indonesia
Published: August 2021

Work discipline can improve company progress. This study aims to determine the influence of employee work discipline on employee performance at PT Bridgestone Pondok Bandar Jambu, Simalungun Regency.This research is a quantitativestudy using all employees as the sample. Data collection techniques is done by distributing questionnaires, observation,and documentation.The results of the data were obtained by using SPSS, the data were tested by validity test, reliability test, Kolmogorov-Smirnov test, normality test, and simple linear analysis. From the research results, there is a significant positive effect of work discipline on employee performance where the magnitude of the influence of the discipline variable is 51.6% while the remaining 48.4 % is influenced by other variables that are not examined in this study such as work environment variables, leadership style,and others.Keywords: Disiplin kerja, kinerja karyawan
Analisa Variasi Nilai Konstanta Komponen Harmonik Tahunan Metode Admiralty dengan Prediksi Elevasi Pasang Surut di Sendang Biru Malang
Authors: Tambunan Russel , Pranowo Widodo S. , Adrianto Dian
Published: August 2021

Metode admiralty merupakan metode pengolahan data pengamatan pasang surut yang dapat digunakan pada rentang waktu pengamatan selama 15 hari atau 29 hari dan menghasilkan 9 komponen pasang surut dan mempresentasikan jenis pasang surut yang terjadi pada suatu lokasi yaitu diurnal K1, P1 dan O1, semi-diurnal M2, K2, S2 dan N2, kuarter-diurnal M4 dan MS4. Penentuan konstanta harmonik pasang surut pada suatu Perairan dengan menggunakan metode admiralty akan menghasilkan variasi nilai dan jumlah konstanta komponen harmonik yang berbeda pada setiap Bulan dalam satu tahun dan berpengaruh pada prediksi elevasi pasang surut.

Pada pengolahan data pengamatan yang dilaksanakan di Perairan Sendang Biru Malang dengan metode admiralty pada setiap Bulan  pada tahun 2020 diperoleh variasi nilai konstanta harmonik yang cukup signifikan dan mempengaruhi hasil data prediksi. Nilai Root Mean Square Error maksimum terjadi pada data prediksi hasil pengolahan konstanta komponen harmonik Bulan     Oktober dan nilai Root Mean Square Error minimum terjadi pada data prediksi hasil pengolahan konstanta komponen harmonik Bulan    Januari. Tipe pasang Perairan Sendang Biru Malang merupakan campuran condong ke harian ganda
METABOLIC EMERGENCIES – PART I
Authors:   3rd Clinic of Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Anton-Paduraru Dana-Teodora
Published: August 2021

Often, patients with metabolic conditions (diseases caused by electrolytic unbalances, endocrine dysfunctions, inborn errors of metabolism) have symptoms similar to other emergencies, particularly as newborns and infants. The authors present the main emergencies: electrolytic unbalances – hypoglycemia, hyponatremia, metabolic acidosis and neonatal hypocalcemia; endocrine dysfunctions – suprarenal insufficiency and neonatal hypopituitarism; inborn metabolic diseases – acidosis, hyperglycemia/ hypoglycemia, hyperammoniemia, clinical symptoms associated to them, and recommended treatment.
ABORDAREA MULTIDISCIPLINARĂ A CONSTIPAŢIEI CRONICE ASOCIATĂ CU INCONTINENŢA FECALĂ LA COPIL
Authors:   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Olaru Claudia , Diaconescu Smaranda ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lupu Valeriu V. ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Gimiga Nicoleta ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Olaru Radian A. ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Păduraru Gabriela ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ignat Ancuţa ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Drug Vasile ,   Institutul de Gastroenterologie şi Hepatologie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Aprodu Gabriel ,   Clinica Chirurgie pediatrică, Spitalul de Pediatrie „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Burlea Marin ,   Clinica a V-a Pediatrie, Spitalul de Pediatrie „Sf. Maria“,  Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: August 2021

Constipaţia este un simptom comun în practica clinică. Definiţia include frecvenţa anormală a tranzitului, dificultate în timpul defecării şi consistenţă anormală a scaunului. Metodele de diagnostic limitate precum şi numeroasele afecţiuni care conduc la apariţia simptomatologiei, duc la creşterea numărului de cazuri cu rezistenţa la tratament. Tratamentul include abordări dietetice şi comportamentale, terapie farmacologică şi în cazuri atent selectate intervenţie chirurgicală. Tratamentul chirurgical este recomandat la pacienţii cu constipaţie severă rezistentă la tratamentul conservator. Confirmarea indicaţiei pentru tratament chirurgical necesită studii privind tranzitul colonic, funcţia de defecare, precum şi efectuarea manometriei anorectale. De aceea, colaborarea strânsă între pediatru, gastroenterolog şi chirurgul pediatru este absolut necesară pentru o evaluare preoperatorie atentă şi corectă a funcţiei gastro-intestinale. Complicaţiile postoperatorii includ obstrucţie intestinală, dureri abdominale, meteorism şi diaree. Eficacitatea intervenţiei chirurgicale şi prevalenţa complicaţiilor postoperatorii sunt determinate de evaluarea atentă preoperatorie a funcţiei gastro-intestinale.
SINDROMUL SMITH-LEMLI-OPITZ. PREZENTARE DE CAZ
Authors:   Universitatea „Lucian Blaga“, Sibiu, Iurian Sorin Ioan ,   Spitalul Clinic de Pediatrie, Sibiu, Ognean Livia ,   Clinica Neonatologie, Spitalul Clinic de Urgenţă, Sibiu, Brunner Han ,   Departamentul Genetică Medicală, Universitatea Radboud, Nijmegen, Olanda, Kluijtmans Leo ,   Laboratorul de Medicină Translaţională, Nijmegen, Olanda, Jira Petr ,   Spitalul Jreoen Bosch, Departamentul Pediatrie, Olanda, Fîntînă Dana ,   Spitalul Clinic de Pediatrie, Sibiu, Mehedinţu Bogdan Ionuţ ,   Spitalul Clinic de Pediatrie, Sibiu
Published: August 2021

Sindromul Smith-Lemli-Opitz (SSLO) reprezintă o afecţiune cu transmitere autozomal-recesivă caracterizată prin multiple anomalii şi care se datorează anomaliilor în sinteza colesterolului. Autorii prezintă particularităţile diagnostice şi terapeutice la un sugar cu ambiguitate genitală.
CLINICAL AND EPIDEMIOLOGICAL PROFILES OF NOVEL VIRUSES IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN
Authors:   Pediatrics Department, “Carol Davila” University of Medicine and Pharmacy, „Grigore Alexandrescu“ Emergency Children’s Hospital, Bucharest, Ulmeanu Alexandru-Ioan , Zapucioiu Carmen ,   Pediatrics Department, “Carol Davila” University of Medicine and Pharmacy, „Grigore Alexandrescu“ Emergency Children’s Hospital, Bucharest, Ulmeanu Coriolan-Emil ,   Pediatrics Department, “Carol Davila” University of Medicine and Pharmacy, „Grigore Alexandrescu“ Emergency Children’s Hospital, Bucharest
Published: August 2021

Viral respiratory tract infections are one of the leading causes of morbidity and mortality in pediatric pathology. The authors provide the latest information on the structure, pathogenesis, clinical features, epidemiology and response to treatment of newly discovered viruses affecting the respiratory tract in children: bocavirus, metapneumovirus, coronaviruses, rhinovirus C.
REFLUXUL GASTROESOFAGIAN LA NOU-NĂSCUT ŞI SUGAR (II)
Authors:   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lupu Valeriu V. , Ignat Ancuţa ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Păduraru Gabriela ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Burlea Marin ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: August 2021

Refluxul gastroesofagian la nou-născut şi sugar se particularizează prin patogenie, încadrare diagnostică şi abordare terapeutică, imaturitatea funcţională a aparatului digestiv, imaturitatea anatomică a sfincterului esofagian inferior Hiss şi aciditatea gastrică mai mică. În cazul sugarilor se ţine cont şi de complianţa redusă la procedurile laborioase cum sunt pH-metria, impedanţ-pH-metria şi endoscopia degestivă. Graniţa dintre regurgitaţii, reflux gastroesofagian fiziologic şi boală de reflux este uneori dificil de trasat. Modificarea stilului de viaţă la sugari (alimentaţia şi modificările poziţionale), prin obţinerea aderenţei mamei la recomandările medicale reprezintă un prim pas în tratamentul RGE, fiind urmat în cazurile non-responsive de terapia farmacologică şi intervenţia chirurgicală.
GASTROESOPHAGEAL REFLUX IN NEWBORNS AND INFANTS (II)
Authors:   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Lupu Valeriu V. , Ignat Ancuta ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Paduraru Gabriela ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Burlea Marin ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: August 2021

Gastroesophageal reflux in newborns and infants is particularized by pathogeny, diagnosis and therapeutic approach, functional immaturity of the digestive tract, the anatomic immaturity of the Hiss lower esophageal sphincter and lower gastric acidity. In infants, the low compliance with the laborious procedures such as pH-metry, impedance – pH-metry and digestive endoscopy is also considered. The border between regurgitations, physiological gastroesophageal reflux and the reflux disease is sometimes hard to establish. Changing the lifestyle of infants (feeding and position changes) based on the mother’s compliance with the medical recommendations is a first step in the treatment of GER, followed in non-responsive cases by pharmacological therapy and surgery
MEDICAL AND SOCIAL IMPLICATIONS OF TEENAGE PREGNANCY
Authors:   “Victor Babes” University of Medicine and Pharmacy, Timisoara, Boia Marioara ,   “Louis Turcanu” Children’s Emergency Hospital, Timisoara, Boia E.S. ,   “Victor Babes” University of Medicine and Pharmacy, Timisoara, Cioboata Daniela ,   “Louis Turcanu” Children’s Emergency Hospital, Timisoara, Manea Aniko ,   “Victor Babes” University of Medicine and Pharmacy, Timisoara,   “Louis Turcanu” Children’s Emergency Hospital, Timisoara
Published: August 2021

Pregnancy in adolescence is a special situation, especially among teenagers who do not benefit from family support, being at risk of not receiving adequate prenatal care during pregnancy, of having complications during pregnancy and birth for the mother and especially for the newborn. Aim. The purpose of this paper is to present the pathology and complications associated to the newborn of teenage mothers. Material and method. Retrospective study of patients hospitalized during January 2013 – December 2014, the study inclusion criteria being maternal age up to 17 years. Results. 66.67% of the newborn in the study were preterm babies and 33.33% were newborn at term. Postpartum complications were more frequent and severe in the preterm newborns versus the newborn at term group. Correlating data about pathology, gestational age and birth weight with biological age of the mother reveals that mothers aged 13-15 years gave birth mostly to premature newborn as opposed to mothers aged 16 to 17 years. Mothers of preterm newborn that had extremely low and low birth weight were aged between 13-15 years. Conclusions. Pregnancy in adolescence is associated most frequently with giving birth to preterm newborn. The lower the biological age of the mother is, the higher the risk of a premature birth, the more severe complications being associated with lower gestational age and lower birth weight of the premature baby.
OSTEO-ARTICULAR DISORDER IN CHILDREN WITH CYSTIC FIBROSIS
Authors:   3rd Clinic of Pediatrics, “G.T. Popa” University of Medicine and Pharmacy, Iasi, Anton-Paduraru Dana-Teodora , Drochioi Ana-Simona ,   3rd Clinic of Pediatrics, “G.T. Popa” University of Medicine and Pharmacy, Iasi, Teslariu Oana ,   3rd Clinic of Pediatrics, “G.T. Popa” University of Medicine and Pharmacy, Iasi, Murgu Alina Mariela ,   2nd Clinic of Pediatrics, “G.T. Popa” University of Medicine and Pharmacy, Iasi, Cernescu Ioana ,   “Sf. Maria” Children’s Emergency Hospital, Iasi, Ifrim Alexandra-Dana ,   “G.T. Popa” University of Medicine and Pharmacy, Iasi, Trandafir Laura Mihaela ,   3rd Clinic of Pediatrics, “G.T. Popa” University of Medicine and Pharmacy, Iasi
Published: August 2021

Osteo-articular disorder in cystic fibrosis is considered a common complication of this pathology. The most efficient strategies used for bone health maintenance in patients with cystic fibrosis are early recognition, prevention and correct treatment. The purpose of this study was the clinical and paraclinical evaluation of patients hospitalized in the 3rd Clinic of Pediatrics, “Sf. Maria” Children’s Emergency Hospital Iasi, diagnosed with cystic fibrosis that exhibited also symptoms of osteo-articular manifestation. The results from this study support the idea that the association of treatment, calcium, multimineral supplements with appropriate hygienic-dietary regimen and with the background therapy of the disease can contribute significantly to better health and wellbeing. Also, non-compliance to treatment among patients and their families significantly contributes to early installation of the complications, including the osteo-articular ones (even from the age of 6 years).
PREEXISTING MATERNAL DISORDERS – RISK FACTORS FOR NEWBORN CONGENITAL ANOMALIES
Authors:   Medical Genetics Department, “Sf. Maria” Emergency Hospital for Children, Iasi, Braha Elena , Luca Alina Costina ,   Pediatric Cardiology Clinic, “Sf. Maria” Emergency Hospital for Children, Iasi
Published: August 2021

Congenital anomalies may be determined by genetic or environmental factors or a combination of the two factors. Maternal disease can affect fetal development through specific effects of metabolic products or maternal antibody transfer. Identifying mothers and pregnancies at risk as well as providing a teratogenic risk discussion and appropriate documentation is aimed at reducing potential teratogenic effects of maternal diseases.
ACUTE GASTROENTERITIS WITH CLOSTRIDIUM DIFFICILE IN A SMALL CHILD WITH HEREDITARY LACTOSE INTOLERANCE
Authors:   University of Medicine and Pharmacy, Targu-Mures, Marginean Maria Oana , Damian Raluca ,   Neonatology Clinic I, Targu-Mures, Dinca Andreea ,   Pediatrics Clinic I, Targu-Mures, Marginean Cristina Oana ,   University of Medicine and Pharmacy, Targu-Mures,   Pediatrics Clinic I, Targu-Mures, Melit Lorena Elena ,   University of Medicine and Pharmacy, Targu-Mures,   Pediatrics Clinic I, Targu-Mures
Published: August 2021

Acute gastroenteritis with Clostridium difficile is insufficiently studied in the specialty literature due to its small incidence at this age, with increased rates of morbidity and mortality. We present the case of a 1 year and 10 month-old child, diagnosed with hereditary lactose intolerance in the neonatal period, admitted in the Pediatrics Clinic I, Targu-Mures, for vomiting, loss of appetite, decreased consistency stools, with a bed smell, with bacterial infection signs in the blood tests and slowly favorable evolution under treatment with cephalosporin. The patient is readmitted after 1 day from discharge with the reappearance of bad smell stools and loss of appetite, with unfavorable evolution after administering a 3rd generation cephalosporin, thus we raise the suspicion of infection with Clostridium difficile, confirmed by the identification of toxins in the stools, with favorable evolution under treatment for anaerobe germs (metronidazole). The particularity of the case consists in the development of a gastroenteritis with Clostridium difficile in a small child (1 year and 10 months), known with retardation in the neuro-psychomotor and language development, repeated episodes of hypoglycemia, with hereditary lactose intolerance which represented a challenge in establishing the diagnosis.
“KISSING-ULCER” – ONSET WITH COMPLICATIONS IN SMALL AGE
Authors:   Pediatrics Clinic I, University of Medicine and Pharmacy, Targu-Mures, Melit Lorena Elena , Marginean Cristina Oana ,   Neonatology Clinic I, Targu-Mures, Damian Raluca ,   Neonatology Clinic I, Targu-Mures, Dinca Andreea ,   Pediatrics Clinic I, University of Medicine and Pharmacy, Targu-Mures, Marginean Maria Oana ,   University of Medicine and Pharmacy, Targu-Mures
Published: August 2021

Ulcer disease is a pathology with low incidence in pediatric population, with an unspecific symptomatology or even absent, thus leading to the development of complications. We present the case of 2 years and 10 month-old male patient, admitted in the regional hospital with the diagnosis of febrile acute gastroenteritis, who in evolution (after 5 days) associated digestive hemorrhage, thus being transferred in the Pediatrics Clinic I, Targu-Mures. The superior digestive endoscopy performed after the hemodynamic and metabolic re-equilibration, pointed out 2 ulcers in the duodenal mucosa, one with active bleeding. The treatment with proton pump inhibitors and the adequate diet initiated determined the patient’s favorable evolution. The particularity of the case consists in the appearance of 2 duodenal ulcers of the duodenal mucosa in a small child, without significant personal history, with adequate life conditions, without associated risk factors and without infection with Helicobacter pylori.
BOLILE MATERNE PREEXISTENTE – FACTOR DE RISC PENTRU ANOMALII CONGENITALE LA NOU-NĂSCUT
Authors:   Cabinetul de Genetică Medicală, Spitalul de Pediatrie „Sf. Maria“, Iaşi, Braha Elena , Luca Alina-Costina ,   Clinica de Cardiologie Pediatrică, Spitalul de Pediatrie „Sf. Maria“, Iaşi
Published: August 2021

Anomaliile congenitale pot fi determinate de factori genetici, de mediu sau de combinaţia dintre cei doi factori. Bolile materne pot afecta dezvoltarea fetală prin acţiunea produşilor metabolici sau datorită transferului de anticorpi materni. Identificarea mamelor şi a sarcinilor cu risc, ca şi oferirea informaţiilor despre riscul teratogen împreună cu o documentare adecvată asupra problemei au ca scop reducerea potenţialului teratogen al bolilor materne.
OBEZITATEA ŞI DISLIPIDEMIILE LA COPILUL CU HEPATITĂ CRONICĂ
Authors:   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Azoicăi Alice N. , Stana Bogdan A. ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Popovici Paula ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ioniuc Ileana K. ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Alexoae Monica M. ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Crişcov Irina ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Murgu Alina M. ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Moraru Evelina ,   Clinica II Pediatrie, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: August 2021

Asocierea hepatitelor cronice cu diverse tipuri de dislipidemii este o realitate nu numai pentru pacientul obez,la care ne aşteptăm să găsim hipercolesterolemii sau/şi hipertrigliceridemii, dar şi pentru copilul normoponderal. Cauzele acestei asocieri sunt multiple, însă trebuie să avem în vedere, în primul rând, predispoziţia familială şi transmiterea genetică a unor forme de dislipidemii. În acelaşi timp, unele dislipidemii sunt secundare hepatopatiilor cronice, astfel că se formează un cerc vicios în care tratamentul de primă intenţie a dezechilibrelor metabolice este de mare importanţă în succesul terapiei antivirale.
SISTEMUL DE CLASIFICARE A FUNCŢIEI MOTORII GROSIERE ŞI SISTEMUL DE CLASIFICARE A ABILITĂŢII MANUALE ÎN EVALUAREA PARALIZIEI CEREBRALE
Authors:   Clinica de Neurologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii ,,Sfânta Maria“, Iaşi, Grigore Ioana , Diaconu Georgeta ,   Clinica de Neurologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii ,,Sfânta Maria“, Iaşi, Prazaru Cătălin ,   Clinica de Neurologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii ,,Sfânta Maria“, Iaşi, Mania Alexandra ,   Clinica de Neurologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii ,,Sfânta Maria“, Iaşi, Ulinici Ana ,   Clinica de Neurologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii ,,Sfânta Maria“, Iaşi
Published: August 2021

Paralizia cerebrală (PC) este o boală cerebrală cronică, definită ca un grup de afecţiuni motorii neprogresive care debutează în primul an de viaţă şi care sunt secundare leziunilor survenite la un creier aflat în dezvoltare. La vârsta pediatrică este principala cauză a tulburărilor motorii severe şi invalidante. Obiectivul lucrării. Încadrarea comparativă în diverse grade de severitate a PC la copil aplicând cele două clasificări: Sistemul de Clasificare a Funcţiei Motorii Grosiere (Gross Motor Function Classification System – GMFCS) şi Sistemul de Clasificare a Abilităţii Manuale (Manual Ability Classification System – MACS). Material şi metodă. Grupul de studiu a cuprins 129 de copii (43 de fete şi 86 de băieţi), cu vârste cuprinse între 2-18 ani, diagnosticaţi cu diferite forme de PC. Protocolul de studiu a inclus examen clinic general şi examen neurologic. Rezultate. Dintre pacienţii cu PC urmăriţi, 24 (18,60%) au fost încadraţi la gradul I atât în clasificarea GMFCS, cât şi în MACS. De asemenea, dintre cei 69 de copii care puteau merge independent (GMFCS I+II), 60 aveau dexteritate manuală bună sau foarte bună (MACS I+II). În formele severe de PC (GMFCS V), 32/35 bolnavi nu puteau mânui obiectele fiind încadraţi în MACS V şi 3 puteau manipula numai anumite obiecte, fiind incluşi în MACS IV. Concluzii. Funcţia motorie grosieră şi abilitatea manuală evoluează pe paliere diferite de gravitate în funcţie de tipul PC. În PC diskinetică, ataxică şi mixtă, s-a remarcat o mai mare corespondenţă între gradele de severitate conturate de cele două clasificări.