bluuebunny/crossref_metadata_2025 huggingface dataset:
Byt przygodny, czyli dialog rozumiany analogicznie w tomikach wierszy ks. Jana Wala
Authors: Bolińska Marta
Published: January 2025

Father Professor Jan Wal (1942–2023) became known as an expert and lecturer in pastoral theology and sociology of religion (e.g. UPJPII in Kraków), a clergyman open to the needs of the faithful, a teacher of young academics, but also a talented poet. The volumes of poems published by the Czuwajmy publishing house near Krakow in 2013–2014 are proof of the artist’s sensitivity and the power of his words. Although he had been reading literature all his life, it was only after the age of 70 that he decided to publish a kind of pentateuch, i.e. over 500 works constituting a guide to his spiritual development and dialogical conclusions. He collected them into volumes, each of which he carefully considered and arranged, also providing a Foreword, Afterword and Information. The collected poems are also an invitation to conversation and reflection among readers, who can look into the private world of a priest conducting a “dialogue understood analogically”, i.e. one in which attention is drawn not to the form, but to the content subordinated to it.
Żale serdeczne Oblubienice bojującej… Walentego Bartoszewskiego jako przykład barokowego zbioru wielkopostnych lamentów
Authors: Kardasz Monika
Published: January 2025

The article is an analysis and interpretation of the collection of poems Żale serdeczne Oblubienice bojującej… by the Vilnius Jesuit Walenty Bartoszewski in genological terms. The starting point is the assumption that Baroque lyrical collections of passion poetry concentrate the most important passion themes and motifs of Baroque literature. The author examined the structure of the volume, pointed out the most important motifs used in the collection and their intertextual references. Attention was also paid to the function of the work in relation to the broadly defined culture of passion in the 17th century.
$\star$-Ricci-Yamabe solitons on almost coK\"{a}hler manifolds
Authors: De U.c. , Blaga Adara M. , Sarkar Avijit , Mandal Tarak
Published: January 2025

The aim of the present article is to analyze $\star$-Ricci-Yamabe solitons on almost coK\"{a}hler manifolds and to characterize them when the potential vector field is pointwise collinear with the Reeb vector field. It is proved that a compact almost coK\"{a}hler manifold admitting $\star$-Ricci-Yamabe soliton under certain restriction on $\star$-scalar curvature is coK\"{a}hler and $\star$-Ricci flat; in addition, that the soliton is steady. $(\kappa, \mu)$-almost coK\"{a}hler manifolds admitting such solitons are also considered and finally, the obtained results are supported by non-trivial examples.
Spectral Properties of The Finite System of Klein-Gordon S-Wave Equations with Condition Depends on Spectral Parameter
Authors: Bayram Elgiz , Kır Arpat Esra
Published: January 2025

The spectral characteristics of the operator L is studied where L is defined within the Hilbert space L2(R+,CV ) given by a finite system of Klein-Gordon type differential equations and boundary condition depends on spectral parameter. The research of the Klein-Gordon type operator continues to be an important topic for researchers due to the range of applicability of them in numerous branches of mathematics and quantum physics. Contrary to the previous works, we take the potential as complex valued and generalize the problem to the matrix Klein-Gordon operator case. The spectrum is derived by determining the Jost function and resolvent operator of the prescribed operator. Further, we provide the conditions that must be met for the certain quantitative properties of the spectrum.
Differentiating under q–integral sign
Authors: Rajković Predrag , Marinkovic Sladjana D.
Published: January 2025

The Leibniz integral rule enables us to interchange the order of differentiation
and integration under some differentiability of the functions. It can be very useful in the
computing the exact value of certain integrals.
In this paper we will present analogs of such rule for q-integrals with functional borders
and their properties.
SOME CLASSIFICATIONS FOR GAUSS MAP OF TUBULAR HYPERSURFACES IN E^4_1 CONCERNING LINEARIZED OPERATORS L_k
Authors: Kazan Ahmet , Altın Mustafa , Turgay Nurettin Cenk
Published: January 2025

In this study, we deal with the Gauss map of tubular hypersurfaces in 4-dimensional Lorentz-Minkowski space concerning the linearized operators L_1 (Cheng-Yau) and L_2. We obtain the L_1 (Cheng-Yau) operator of the Gauss map of tubular hypersurfaces that are formed as the envelope of a family of pseudo hyperspheres or pseudo hyperbolic hyperspheres whose centers lie on timelike or spacelike curves with non-null Frenet vectors in E^4_1 and give some classifications for
these hypersurfaces which have generalized L_k 1-type Gauss map, first kind L_k-pointwise 1-type Gauss map, second kind L_k-pointwise 1-type Gauss map and L_k-harmonic Gauss map, k ∈ {1,2}.
A classification of generalized skew-derivations on multilinear polynomials in Prime Rings
Authors: Dhara Basudeb , Sandhu Gurninder S. , Bera Nripendu
Published: January 2025

In this article, we are intended to examine generalized skew-derivations that act as Jordan homoderivations on multilinear polynomials in prime rings. More specifically, we show that if $F$ is generalized skew-derivation of a prime ring $R$ with associated automorphism $\alpha$ such that the relation $F(X^2)=F(X)^2+F(X)X+XF(X)$
holds for all $X\in f(R)$, where $f(x_1,\ldots,x_n)$ is a noncentral valued multilinear polynomial over extended centroid $C$, then either $F=0$ or $F=-id_{R}$ or $F=-id_{R}+\alpha$ (where $id_{R}$ denotes the identity map of $R$).
Hankel Operators Between Köthe Spaces
Authors: Doğan Nazlı
Published: January 2025

This paper is about the operators defined between Köthe spaces whose associated matrix is a Hankel matrix. After demonstrating
how these operators are defined, the conditions for continuity and compactness of these operators are constructed. It is shown that the backward and forward shift operators are mean ergodic and Ces´aro bounded by establishing a relationship between the backward and forward shift operators and Hankel and Toeplitz operators on power series spaces.
STREAMING MICROSCOPIC IMAGE DATA TO THE CLOUD STORAGE FOR DETECTION OF ACUTE LYMPHOBLASTIC LEUKEMIA USING CNN
Authors: Kravchenko P. , Burlachenko I.
Published: January 2025

Abstract. In the modern world, the problem of the prevalence of cancer remains quite widespread, including acute lymphoblastic leukemia. It is very important to diagnose such diseases in the early stages in order to prescribe timely treatment and achieve patient remission. However, the problem that remains to this day is that the diagnosis of the disease based on microscopic images of a human blood smear are manual. This method of diagnosis is prone to errors due to many factors, due to inattention, absence of a specialist in the locality, etc. Therefore, the need for automated data collection of microscope images and their analysis with high accuracy is urgent. Research into the creation of low-cost devices and the creation of neural network architectures that can control the process of analysis and disease detection. It is proposed to develop a network consisting of hardware and software capable of transferring acquired data from the microscope to cloud storage for further use by a convolutional neural network to classify human blood smear images to detect healthy or blast blood cells. A hardware and software complex has been developed for collecting and transferring values from the microscope to cloud storage. The main module for receiving and transferring data to the cloud is a Raspberry Pi single-board computer that works on Wi-Fi technology. In conclusion, the proposed system is capable of ensuring the effectiveness of diagnosing blood cancers not only of lymphoblastic leukemia, but also of other types.
INFORMATION AND SOFTWARE OF VIRTUAL REALITY TRAINING APPLICATION «NATURAL GAS DRYER PLANT»
Authors: Kuzmuk D. A. , Shovkoplias O. A. , Kuzikov B. O.
Published: January 2025

Abstract. Traditional training methods for natural gas dehydration plant operators have several limitations. Theoretical training may need to provide more insight into real-world working conditions, while practical training can be dangerous or require significant financial investment. Virtual reality (VR) technology offers a potential solution to this challenge by enabling the replication of the natural gas dehydration plant experience in a safe, immersive digital environment. This research project has developed a software application that simulates the operation of a natural gas dehydration plant using VR technology. The article describes the world background and possible alternatives for the project's hardware and software implementation. Finally, the virtual environment was created using the Unity game engine, which incorporates Open VR and VRTK plugins to enable user interaction and navigation. The application allows users to explore the plant freely, interact with equipment and tools, perform standard operating procedures, and respond to emergency scenarios. The project has several scenarios controlled by the tutor that need to be solved by the student. All scenarios involve visual effects to increase immersion. A multi-user mode and voice chat functionality have also been implemented to facilitate collaborative learning. The development of this VR training application addresses the need for practical, hands-on learning in the natural gas industry, where actual equipment can be prohibitively expensive or hazardous. By providing a realistic, interactive virtual environment, the application aims to enhance the skills and understanding of natural gas dehydration plant operators, improving safety and operational efficiency. The application was developed on request and in close cooperation with the Department of Chemical Engineering at Sumy State University. The findings from this research can serve as a basis for further development of VR applications in various industrial and educational domains.
ADAPTIVE VISION AI
Authors: Vodyanitskyi V. , Yuskovych-Zhukovska V.
Published: January 2025

Abstract. As of today, computer vision systems are continuously developing and systematically improving. Machines see visual content in the form of numbers, in which each pixel represents its own piece of information. Computer vision, as a component of artificial intelligence, allows machines to see, observe and understand everything. It enables computer systems to obtain useful information from digital images, video, visual data and perform programmed actions. Computer vision technologies rely on pattern recognition, machine learning, and neural networks to allow computers to break down images, interpret data, and identify features. Tracking moving objects and their identification is a difficult task, as it requires the accuracy of pattern recognition. An untrained computer vision algorithm is unable to understand the relationship between the shapes in the image and the objects. Therefore, the algorithm must be trained. The paper considers models that are trained on a high-performance computing cluster with GPU support. The developed open source software allows detection, tracking and recognition of blurry moving objects with the help of artificial intelligence that adapts to any video camera. A significant increase in accuracy is achieved thanks to machine learning.
RESEARCH OF THE INFLUENCE OF MODERN TRENDS IN UI/ UX DESIGN OF MOBILE APPLICATIONS ON USER’S MOOD
Authors: Zhadan A. S. , Sichkar O. O. , Pishkin D. A.
Published: January 2025

Abstract: The research explores the impact of modern trends in UI/UX design on the mood of users interacting with mobile applications. Through an analysis of literature and a survey of IT students, the study evaluates the emotional resonance of seven contemporary UI/UX styles: brutalism, neubrutalism, Bauhaus, neumorphism, retrofuturism, cyberpunk, and glassmorphism. Each design trend is characterized by unique visual and functional elements that influence user experiences.
The methodology involved presenting survey participants with interface examples representing each trend. They assessed these designs based on visual appeal, usability, engagement, and emotional impact. Key findings reveal distinct emotional responses to each trend: cyberpunk and retrofuturism evoked excitement, Bauhaus and flat design inspired calmness, while neumorphism and glassmorphism were appreciated for aesthetics but raised usability concerns. Generational differences were also noted, with younger users favoring experimental styles and older users preferring minimalistic designs.
The study emphasizes the importance of balancing aesthetics and functionality, tailoring designs to target demographics, and ensuring accessibility for diverse users. It highlights how thoughtful design choices can evoke positive emotions, enhancing user satisfaction. These insights contribute to the growing understanding of the psychological impact of UI/UX design and its role in creating emotionally engaging digital experiences.
PYTHON PROGRAMMING LANGUAGE AS A MEANS OF TRAINING FUTURE TEACHERS OF COMPUTER SCIENCE WHEN WORKING WITH ARDUINO
Authors: Kyslitsyn V. , Shevchenko L. , Umanets V.
Published: January 2025

Abstract. This article explores the possibilities and advantages of using the Python programming language together with Arduino robotics kits in the process of training future computer science teachers in pedagogical educational institutions. Considerable emphasis is placed on analyzing the principles of operation of the simplest programs and devices that can be used to visualize the possibilities of using the Arduino platform and Python libraries to create robots that can be implemented in the educational process and everyday life. The authors have developed the program code and presented a working model of a robot assembled and programmed on the basis of Arduino components to measure humidity in computer laboratories and create automatic plant irrigation systems to maintain proper conditions in classrooms. The article presents an example of integrating the learning of the Python programming language with the use of Arduino robotics kits. This method is aimed at improving the quality of training of future computer science teachers, expanding their methodological arsenal and ensuring the ability to teach students using innovative means. The results of the study and the developed teaching and learning materials will help to interest students in STEM education and prepare a new generation of computer science teachers for the challenges of the modern technological world, expand their methodological arsenal and develop the ability to use integrated technical, engineering and mathematical solutions to solve theoretical and practical problems. In addition, this study can serve as a guide to popularize the use of Arduino and Python in educational institutions, and encourage future computer science teachers to implement STEM and hands-on teaching methods, which will contribute to better student learning and improve the quality of professional education in the field of information technology in general. In general, the study opens up a wide range of opportunities for using modern digital technologies in professional education and stimulates interest in STEM education among computer science teachers and students, thereby contributing to the development of a new generation of engineers and technology leaders. Further research could be aimed at developing specific training courses and methods for integrating the Python programming language and Arduino robotics kits into STEM education. It is important to create interdisciplinary STEM courses with the participation of teachers of computer science, physics, mathematics, vocational education in the IT industry, etc.
CHARACTERISTICS OF THE BLOOD PLASMA "LIPID PEROXIDATION - ANTIOXIDANT PROTECTION" SYSTEM DEPENDING ON NASAL MUCOSA MICROFLORA COMPOSITION IN VARIOUS CHRONIC RHINITIS PHENOTYPES
Authors: Smirnova Olga , Goncharova Natalia
Published: January 2025

Abstract
Chronic rhinitis is the most common ENT disease. Over the past decade, there has been an increased incidence of chronic rhinitis. In all forms of chronic rhinitis, there is a decrease in the protective properties of nasal mucous membrane, which can be accompanied by activation of nasal bacterial microflora. Dysbiosis of nasal mucous microbiota contributes to the development of inflammation, activation of immune cells with the development of immune reactions, activation of lipid peroxidation processes and changes in the activity of antioxidant defense factors in nasal cavity and blood. There is evidence that different phenotypic variants of chronic rhinitis are characterized by own specific spectrum of microorganisms in the nasal cavity, which significantly affects the course of diseases, as well as the state of the POL-AOZ system. The aim of our work was to comparatively assess quantitative composition of the microbial flora and indicators of the POL-AOZ system in patients with various forms of chronic rhinitis. The article presents the results of a laboratory examination of 165 patients with chronic rhinitis, including 45 patients with chronic allergic rhinitis, 49 patients with chronic vasomotor rhinitis, 32 patients with chronic atrophic rhinitis, and 39 patients with chronic infectious rhinitis. The control group consisted of 40 apparently healthy donors. In accordance with the study design, at the first stage, all subjects underwent a bacteriological examination of nasal mucous membrane and a quantitative assessment of the isolated microflora representatives. At the second stage, the LPO-AOP indices were determined in the blood plasma using a spectrophotometric method. Statistical analysis of the obtained results was performed using the Statistica 8.0 software package. To assess differences in the groups, the Kruskal-Wallis, Mann-Whitney, and Wilcoxon nonparametric tests were used. The critical level of statistical significance for testing scientific hypotheses was considered equal to p˂0.05. The data are presented as a median (Me) and interquartile range (Q25 – Q75). Changes in nasal mucosa microbiome induce a decrease in the activity of antioxidant defense factors in all studied phenotypic forms of chronic rhinitis. In cases of chronic allergic, vasomotor and infectious rhinitis, a significant increase in the level of both primary and secondary lipid peroxidation products is observed. Studies show that the greatest increase in lipid peroxidation activity is recorded in chronic infectious rhinitis, as well as the greatest nasal mucosa dysbiosis is revealed in this phenotype. Thus, the leading pathogenetic mechanism in chronic rhinitis is presented by hypoxia due to intermittent nasal congestion, which contributes to changes in the POL-AOZ system. At the same time, activated microbial flora also contributes to aggravation of such changes.
DYNAMIC OBSERVATION OF UPPER AIRWAYS COLONIZATION IN A CYSTIC FIBROSIS PATIENT INFECTED WITH ROSEOMONAS AEROFRIGIDENS UNDER TARGETED THERAPY
Authors: Dzhovmardova Ekaterina Dmitrievna , Sergeeva Marta Vladimirovna , Kondratenko Olga Vladimirovna , Zalevskiy Igor Vitalievich , Nikitina Tatyana Rudolfovna
Published: January 2025

Abstract
Cystic fibrosis (CF) is a disease characterized by a varying microbiological diversity, including bacteria such as Pseudomonas aeruginosa, Burkholderia cepacia complex, Achromobacter xylosoxidans/ruhlandii. Additionally, there are microorganisms with unknown clinical significance, including Roseomonas aerofrigidens. The main goal of the study is to evaluate the prevalence of such microorganisms among CF patients undergoing regular examinations at the microbiological laboratory of the Samara State Medical University, Ministry of Health of the Russian Federation. An analysis of 12,094 clinical material cultures was carried out, with identification done by using MALDI-ToF mass spectrometry. A composite correlation index was calculated. The Jaccard similarity coefficient was used to assess the nature of symbiotic or antagonistic interactions.
A total of 20 strains of Roseomonas spp. bacteria was isolated. Four strains were obtained from the mucous membrane of the posterior pharyngeal wall, while the remaining strains – from nasal lavage fluid. The patient with F508del/F508del genetics had been receiving dual targeted therapy since October 2022. Before treatment, no clinically significant Gram-negative species or Roseomonas aerofrigidens strains were noted in the patient’s anamnesis. However, during observation, Roseomonas aerofrigidens cultures were obtained from nasal lavage fluid at the third, fifth, sixth, eighth, ninth, eleventh, and eighteenth months of observation, with no concurrent bacterial strain growth in sputum samples.
The study of the protein profiles demonstrated a high degree of kinship among the isolates, with a correlation index exceeding 0.8, confirming the hypothesis on long-term colonization of the paranasal sinuses by same Roseomonas aerofrigidens strain. While assessing the consistency criterion, it was found that among 30 microbial species isolated from nasal lavage fluid over 18-month observation, two microorganisms were classified as representatives of the constant microbiota, four (including Roseomonas aerofrigidens) as additional microbiota. The remaining species belong to random microbiota. Based on the Jaccard coefficient, it was found that four pairs of microorganisms are characterized by a synergistic nature of the relationship. These observations demonstrate a case of multi-month colonization with a unique strain of Roseomonas aerofrigidens in a patient with cystic fibrosis receiving targeted therapy.
FIRST DATA ON THE MOLECULAR GENETIC DIVERSITY OF HHV6B AND ITS IMPACT ON THE CLINICAL AND LABORATORY COURSE OF MONONUCLEOSIS-LIKE SYNDROME IN CHILDREN
Authors: Filatova Elena N. , Sakharnov Nikolai A. , Suslov Nikita A. , Popkova Mariia I. , Utkin Oleg V.
Published: January 2025

Human herpes virus 6B (HHV6B) is a ubiquitous causative agent of mononucleosis-like syndrome (MLS) and other diseases. The diversity of HHV6B infection may be due to virus genetic polymorphism. Molecular genetic diversity of circulating HHV6B, as well as its impact on the clinical and laboratory features of HHV6B infection have not been studied. The aim of the work was to study the intraspecific diversity of HHV6B circulating among children in Nizhny Novgorod (Russia) region, and to investigate its effect on MLS clinical and laboratory features. Blood leukocytes and saliva DNA samples from healthy children and children with HHV6B infection were analyzed for HHV6B DNA detection. Original intraspecific HHV6B classification based on detecting signature nucleotide substitutions in the sequence of the U90 gene fragment, was used for virus typing. A relationship between HHV6B genovariant and clinical/laboratory MLS characteristics was studied using multivariate statistical methods. Circulation of four HHV6B genovariants was shown among children in Nizhny Novgorod region: HHV6B/GV2e, HHV6B/GV2b (dominant genovariants), HHV6B/GV1a and HHV6B/GV2a (minor genovariants). Children with MLS infected with HHV6B/GV2e genovariant were more likely to have laboratory signs of cytolysis and increased peripheral blood lymphocyte count. Children with MLS infected with the HHV6B/GV2b genovariant were more likely to have higher mature neutrophil level. An increase of HHV6B viral load in leukocytes was accompanied by aggravated intoxication symptoms. Co-infection with the Epstein-Barr virus (EBV) led to more severe symptoms of acute tonsillitis, hepatosplenomegaly, and lymphadenopathy. Patients with EBV were more likely to have higher ALAT and lymphocyte level along with decreased mature neutrophil count. In children with MLS, EBV coinfection caused smaller HHV6B viral load in blood leukocytes (in children with HHV6B DNA 10 or more copies/105 cells) and lower HHV6B DNA detection frequency in saliva (in children with HHV6B DNA less than 10 copies/105 leukocytes). The results show the influence of genetic HHV6B polymorphism upon the clinical and laboratory features of MLS in children, and also demonstrate that HHV6B/GV2e and EBV cause similar disease symptoms.
METHOD FOR PHENOTYPIC IDENTIFICATION OF ACINETOBACTER SEIFERTII BACTERIA
Authors: Sivolodskii Evgeny Petrovich , Kraeva Lyudmila Aleksandrovna , Melnicova Elena Vladimirovna
Published: January 2025

Abstract. The aim of the study is to increase the accuracy of Acinetobacter seifertii species identification by the phenotypic method. Study objects: 5 strains of A. seifertii (3 isolated in the microbiological laboratory at the Military Medical Academy, 2 strains obtained from the Pasteur Institute (St. Petersburg)). Clinical strains of the A. baumannii group (Ab group) isolated at the Military Medical Academy in 2023-2024 were also studied: A. baumannii (n=152), of which 37 strains of the tryptophandestruens biovar, A. nosocomialis (n=12), A. pittii (n=6), 3 strains of A. calcoaceticus from the Neva River. The type of such strains was determined by MALDI-TOF mass spectrometry. The belonging of the strains to the Ab group was established by taxonomic tests. The biovar A. baumannii bv. tryptophandestruens was determined by a chromogenic reaction on sodium benzoate-containing nutrient medium. Urease of rapid activity was detected by a micro-volumetric method assessed 3 hours later. Utilization of D-xylose as the only carbon source was determined on a nutrient medium containing (g/l): D-xylose 2.0; NH4CI 5.0; NH4NO3 1.0; Na2SO4 2.0; K2HPO4 3.0; KH2PO4 1.0; MgSO4 0.1; bromothymol blue 1.6% aqueous solution 4 ml; bacteriological agar 15.0; distilled water 1 l; pH 7.2 ± 0.2; sterilization at 112oC 20 min. A pure bacterial culture was studied, in which signs of the Ab group and growth on a sodium acetate-containing nutrient medium were previously detected (control of no auxotrophy). The agar bacteria culture was suspended in 0.1 ml of 0.85% sodium chloride solution, one loop of bacterial suspension was sown with a stroke on a nutrient medium with D-xylose and a medium without D-xylose (control), incubated aerobically at 30oC 24-48 hours. The absence of bacterial growth on a medium with D-xylose and a medium without D-xylose in the presence of their growth on a nutrient medium with sodium acetate indicates belonging to the species A. seifertii. Studies showed that all A. seifertii strains do not utilize D-xylose, and all strains of other species of the Ab group utilize D-xylose. A. seifertii bacteria do not utilize L-arabinose, however, 29.6±3,7% of A. baumannii strains do not utilize L-arabinose, including all 37 strains of the tryptophandestruens biovar, which determines the unreliability of this test for the identification of A. seifertii. Most strains of A. seifertii (4 out of 5) have a urease of rapid activity, which suggests their proximity to the species A. nosocomialis. A method has been developed for identification of A. seifertii bacteria based on a set of phenotypic features of Ab group bacteria with a test for D-xylose utilization. It has been established that the use of the D-xylose utilization test in conjunction with the detection of rapid urease activity allows to accurately identify the bacteria A. seifertii and A. nosocomialis among other species of the Ab group.
NEW APPROACHES FOR COMBATING POLYRESISTANT ESKAPE PATHOGENS
Authors: Konkova Lidia Sergeevna , Rogacheva Elizaveta Vladimirovna , Kraeva Lyudmila Alexandrovna
Published: January 2025

Antibiotic resistance of microorganisms is the most pressing global health problem due to the ever-increasing number of deaths caused by ineffective antibiotic therapy. The COVID-19 pandemic has only exacerbated pre-existing issue of increasing resistance of bacterial strains worldwide. Lack of public awareness about proper use of antibiotics directly impacts on uncontrolled antibiotic administration associated with weak antibiotic dispensing controls as well as limited access to health facilities in low- and middle-income countries. It is reported that 68.9% of COVID-19 patients used antibiotics for prophylaxis against bacterial complications or to treat coronavirus infection (mainly azithromycin and ceftriaxone) before hospitalization, with a self-medication rate of 33.0%. The most antibiotic-resistant and dangerous to global public health group of microorganisms is known as ESKAPE: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter species. The proportion of resistant strains among these microorganisms can reach 95%. In light of the rapid increase in the number of infections caused by antibiotic-resistant strains, a need to create new antibacterial drugs is the most urgent task.
The development of new antibiotics is a high-cost goal and it’s often ineffective. Therefore, more and more often their developers resort to the use of antibiotics combinations or using them together with adjuvants of different mechanisms of action. In recent years, special devices and coatings with nanoparticles of various metals deposited on their surface have become increasingly widespread. Some successes achieved in the use of antimicrobial peptides have been leveled by the loss of activity in the human body and their high production cost. In this regard, the use of bacteriophages, especially in combination with antibiotics, has been becoming a promising approach. The observed synergism both in vitro and in vivo experiments allow to hope for certain successes in the fight against ESKAPE group multidrug-resistant pathogens.
Coastal mortality of Pacific walruses at the Cape Vankarem haulout and influencing factors in 2017–2020
Authors: Zagrebelniy S. V.
Published: January 2025

Analysis of short-term threats to the welfare of a group of Pacific walruses (Odobenus rosmarus divergens Illiger, 1815) at the Cape Vankarem haulout showed significant changes in the structure and strength of sources of disturbance to the animals appeared over the 10 years since the last survey. Anthropogenic disturbance from passenger helicopters and traditional hunting (by spear slaughter) has decreased. The main sources of disturbance have been utilities and “northern importation”, which has increased mortality, especially of young animals. It is significantly higher than in haulouts remote from populated areas. Polar bears and local dogs are the next sources of concern.
Impacto de fatores ocupacionais na depressão pós-parto: uma revisão sistemática
Authors: Laguna Gabriela Garcia de Carvalho , Tavares Beatriz Rihs Matos , dos Santos Karol Maynne Vieira , Paulo Karen Kessy de Souto , Fonseca Yago Soares , Maia Michele Cristina , Borges Grasiely Faccin
Published: January 2025

RESUMO Objetivo: Objetivou-se descrever como fatores relacionados à ocupação profissional de mulheres impactam no desenvolvimento de depressão pós-parto. Métodos: Trata-se de uma revisão sistemática realizada sob o protocolo PRISMA e registrada na plataforma PROSPERO (ID: CRD42022371262). A busca foi realizada nas bases de dados PubMED e SciELO, além das disponíveis na BVS, foram incluídos estudos observacionais publicados entre 2012-2024 nos idiomas português, inglês ou espanhol. A qualidade dos estudos foi avaliada a partir da escala ROBINS-I. Resultados: Foram triados 1425 artigos e selecionados 23, a partir dos quais identificou-se que baixa satisfação, estresse psicossocial, exaustão, remuneração reduzida, alta carga, condições precárias e superinvestimento no trabalho são fatores ocupacionais que podem contribuir para a depressão pós-parto; além de desemprego, busca mal sucedida por trabalho e necessidade de deixar a ocupação para cuidar do recém nascido. Recompensas no trabalho e aumento da licença à maternidade foram descritos como fatores protetores para a depressão pós-parto. Conclusão: Com base nas análises discutidas, há uma nítida associação entre o risco de depressão pós-parto em relação à situação ocupacional da mulher. Ainda, diante do caráter multifatorial na gênese desse transtorno, a situação ocupacional pode tornar-se fator desencadeador ou agravante da situação de saúde mental da mulher.
Patologias não neoplásicas e neoplásicas da bolsa testicular na ressonância magnética: um ensaio iconográfico
Authors: Caetano Thiago de Oliveira , Schuch Alice , Pedrollo Ivan Morzoletto
Published: January 2025

Resumo A ressonância magnética é uma ferramenta importante na avaliação da bolsa testicular em casos com achados inconclusivos pela ultrassonografia. A capacidade da ressonância magnética de diferenciar entre lesões intratesticulares e extratesticulares, bem como entre condições neoplásicas e não neoplásicas, tem papel crucial na caracterização de lesões, no estadiamento de tumores e auxilia na decisão pré-operatória. Este ensaio apresenta imagens de ressonância magnética que destacam as principais patologias não neoplásicas e neoplásicas. O reconhecimento dessas patologias reforça o papel do médico radiologista na linha de cuidado de pacientes com lesões da bolsa testicular mediante uma avaliação adequada das suas características de imagem.
CARDIOVASCULAR RISK BEFORE AND AFTER SURGICAL TREATMENT OF SEVERE OBESITY
Authors: CARDIA Lilian , GADDUCCI Alexandre Viera , PAJECKI Denis , SANTO Marco Aurelio , DE CLEVA Roberto
Published: January 2025

ABSTRACT BACKGROUND: Obesity is a predisposing factor for serious comorbidities, particularly those related to elevated cardiovascular mortality. The atherogenic index of plasma (AIP) has been shown to be a useful indicator of patients with insulin resistance. AIMS: The aim of this study was to assess cardiovascular risk before and after surgical treatment of obesity. METHODS: A total of 615 patients undergoing bariatric surgery between 2007 and 2012 were evaluated using the analysis of electronic records (triglyceride/high-density lipoprotein cholesterol) before and after surgery. The AIP levels >3.5 mg/dL for men and >2.5 mg/dL for women were insulin-resistant and predisposed to cardiovascular events. RESULTS: A total of 117 men had an AIP >3.5 mg/dL during the preoperative period, 13.5% during the early postoperative period, 14.3% during the intermediate period, and 18.2% during the late postoperative period. Among 498 women, 56.2% had an AIP >2.5 mg/dL before surgery, 17.9% in early postoperative period, 13.5% in the intermediate period, and 11.4% in the late period. CONCLUSIONS: Bariatric surgery resulted in a significant effect on the AIP, insulin resistance, metabolic syndrome, and therefore, the risk of cardiovascular diseases.
SOUTHERN VOICES: SUBVERSIVE LITERACIES OF MIGRANT WOMEN IN ADULT EDUCATION
Authors: Martins Neto Irando Alves
Published: January 2025

ABSTRACT Street’s (1984) concept of “ideological model” advocates for the plural character of literacy, validating all models of writing. From this perspective, marginalized literacy practices are as legitimate as dominant literacy practices, despite being socially stigmatized. In this article, I aim to investigate in what ways the literacy narratives of two adult students transgress social and linguistic norms. I employ a narrative analysis methodology that incorporates the discursive, situated and performative nature of the stories (MOITA LOPES, 2021) I analyze. At the social level, access to reading and writing is, for the students, a subversion of imposed norms that deprived them of the right to education. As women who migrated from the northeast to the southeast of Brazil in search of better living conditions, returning to school and learning to read and write are acts of resistance that challenge the status quo. At the linguistic level, the students reaffirm their enunciative intentions by transgressing the standard norm of the language, expanding the possibilities of meaning in their texts through the subversive use of punctuation and deixis. The outcomes emphasize the need to recognize the students’ literacy journey as a social criticism against insufficient policies on the provision of quality education for all. Furthermore, the outcomes point to the need for language teaching and learning approaches that recognize non-institutionalized models of literacy as valid knowledge that enhances and enriches language learning, minimizing the abyssal line (SANTOS, 2010) between orality and literacy as well as between school and non-school knowledge.
Casos de câncer gástrico no Brasil e tempos de espera para o diagnóstico e tratamento
Authors: Carvalho Thayana Calixto de , Borges Anne Karin da Mota , Silva Ilce Ferreira da
Published: January 2025

Resumo O objetivo é descrever o perfil sociodemográfico e clínico-epidemiológico dos casos hospitalares de câncer gástrico e analisar fatores associados ao tempo de espera para início do tratamento no Brasil. Estudo exploratório das características sociodemográficas e clinico-epidemiológicas dos casos de câncer gástrico. Os tempos até início do tratamento foram estimados de forma contínua e depois categorizados em ≤ 60/> 60 dias para estimar a prevalência. Os fatores associados ao atraso do tratamento foram avaliados pela regressão logística simples e múltipla. O tempo entre o diagnóstico e o início do tratamento tanto para os casos que chegaram sem diagnóstico e sem tratamento quanto para os que chegaram com diagnóstico e sem tratamento foi menor para os casos cuja primeira intervenção foi cirurgia e para aqueles com estadiamento-III/IV. Os principais fatores associados ao atraso do tratamento foram: idade, região, estado conjugal, escolaridade, município de residência, estadiamento e primeira intervenção recebida. Observou-se disparidade no tempo para início do tratamento de acordo com a primeira intervenção recebida, estadiamento e status de chegada à instituição. Além disso, constatou-se a associação de fatores sociodemográficos e clínicos a um atraso para início do tratamento.
Desigualdades na adequação ao calendário de consultas para crianças menores de 5 anos na Vigilância Alimentar e Nutricional
Authors: Santos Iolanda Karla Santana dos , Mazzeti Camila Medeiros da Silva , Pereira Débora Borges dos Santos , Pastorello Claudia Cristina Gonçalves , Oliveira Mariane Helen de , Conde Wolney Lisbôa
Published: January 2025

Resumo O Ministério da Saúde propõe um calendário mínimo de consultas na assistência à criança para acompanhamento do crescimento e do desenvolvimento. O objetivo foi analisar a adequação ao calendário mínimo de consultas para crianças menores de 5 anos com pelo menos um acompanhamento antropométrico registrado no Sistema de Vigilância Alimentar e Nutricional (SISVAN) no período de 2008 a 2020. Os indicadores analisados foram a mediana do número de consultas e a adequação da última consulta ao calendário. No Brasil, a mediana de consultas foi igual a três, inferior ao recomendado. Para crianças nascidas a partir de 2008, a adequação da última consulta ao calendário foi de 11,8% com desigualdades, menor na região Norte (5,7%) e maior na região Sul (22,5%). Comparando as unidades federativas, Amapá e Roraima apresentaram as menores frequências, e Paraíba e Paraná as maiores. A adequação da última consulta ao calendário foi maior entre os municípios do quinto mais elevado do PIB per capita. O SISVAN apresenta desigualdades no acesso aos serviços de saúde. A maior adequação ao calendário mínimo de consultas está nas regiões Sul e Sudeste.
Health in the Legal Amazon: an analysis of morbidity and mortality indicators between 2010 e 2021
Authors: Lima Natasha Rayane de Oliveira , Oliveira Beatriz Fátima Alves de , Silveira Ismael Henrique da , Oliveira Igor Neves de , Sousa Ranieri Flávio Viana de , Ignotti Eliane
Published: January 2025

Abstract We carried out the health situation analysis in the Legal Amazon through morbidity and mortality indicators and the comparison between intra and inter-state federation of the region and Brazil. Analysis of the health situation, trends, and identification of clusters in the Brazilian Amazon, for the period from 2010 to 2021, using secondary data available in official health information systems. Circulatory diseases were the main cause of death, representing 23% of deaths. External causes and respiratory diseases contributed 16% and 9% of deaths, respectively; 52.6% of infant deaths occurred in the early neonatal period, and the infant mortality rate remained above the national average. The ratio of maternal mortality was also high and above the national average between 2010 and 2021. The dengue incidence rate remained below the national average with a drop trend of -59.50%. However, rates of Chagas disease, AIDS, Hansen’s disease, American cutaneous leishmaniasis and tuberculosis remained above average rates in the country. It was concluded that the population of the Brazilian Amazon faces health challenges. The findings facilitate the identification of territorial priorities for the implementation of actions that impact morbidity and mortality reduction in the region.
Mulheres lactantes e a percepção do valor útil para o aleitamento materno no espaço prisional
Authors: Santos Marcia Vieira dos , Alves Valdecyr Herdy , Pereira Audrey Vidal , Vieira Bianca Dargam Gomes , Rodrigues Diego Pereira , Calandrini Tatiana Socorro dos Santos , Alcici Rebecca dos Santos , Carmo Raquel Ribeiro de Azevedo Costa do
Published: January 2025

Resumo O objetivo é desvelar o valor útil da amamentação para lactantes no ambiente prisional, a partir da dimensão axiológica de Max Scheler. Pesquisa qualitativa desenvolvida em unidade prisional no Rio de Janeiro, onde foram entrevistadas sete lactantes. A técnica de coleta de dados foi a entrevista fenomenológica e, para análise e tratamento dos dados, utilizou-se a análise de conteúdo de Laurence Bardin. O valor desvelado à luz de Max Scheler foi o valor útil, detectado a partir da carência das lactantes no momento vivido no ato de amamentar no espaço prisional. Sendo, necessária uma transformação desse espaço em um ambiente legítimo, que deverá valorar a amamentação por meio do apoio da família da lactante, de amigos e profissionais de saúde, com a implementação de novos protocolos e políticas públicas específicas para a prática de amamentar no sistema prisional, que devem ser baseadas em evidências científicas e nos princípios do Sistema Único de Saúde.
Entre las calles y RAPS: Revisión integradora sobre el acceso de personas sin hogar a los Servicios de Salud Mental
Authors: Fraga Priscilla Victória Rodrigues , Araújo Maria Cecília Assis de , Souza Anelise Andrade de , Martins Ana Luísa Jorge , Dantas Ana Carolina de Moraes Teixeira Vilela , Marinho Rafaela Alves , Rodrigues Diadorim Maria , Paes-Sousa Rômulo
Published: January 2025

Resumen Esta revisión integradora sistematizó los factores que influyen en el acceso de la Población Sin Hogar (PSH) que hace uso nocivo de alcohol y otras drogas a los servicios de salud mental en la Red de Atención Psicosocial (RAPS) en Brasil, a partir de la categorización de factores en “barreras” y “facilitadores” del acceso. Se seleccionaron 13 artículos correspondientes, con posterior evaluación de su calidad metodológica. Se encontraron 19 barreras y 22 facilitadores de acceso, observándose una convergencia y complementariedad de los factores identificados, sin disensos entre autores. Aunque existen barreras y facilitadores específicos relacionados con el uso de sustancias, la mayoría están vinculados a las condiciones y estilos de vida de la PSH, o a las formas en que los servicios abordan la PSH. Se identificaron como barreras importantes la discriminación, la rigidez burocrática de los servicios y la falta de integración intra e intersectorial. Por otro lado, las Clínicas en la Calle y prácticas como la reducción de daños y el apoyo matricial emergieron como facilitadores notables, adaptándose a las necesidades de los usuarios. Es necesario realizar estudios futuros que profundicen en factores específicos y las relaciones entre estos factores.
Model of care in freestanding birth centers in Brazil: a scoping review
Authors: Aguiar Cláudia de Azevedo , Lopes Gisele Almeida , Bussadori Jamile Claro de Castro , Leister Nathalie , Riesco Maria Luiza Gonzalez , Alonso Bruna Dias
Published: January 2025

Abstract Freestanding birth centers (FBCs) in Brazil are regulated to provide care for women with a straightforward pregnancy. The systematization of the literature on FBCs can broaden our knowledge of these facilities. We conducted a scoping review to answer the following research question: “What are the characteristics of the model of care in freestanding birth centers in Brazil?”. Relevant studies covering any period and in any language were included. Searches were performed of platforms, databases, repositories, and institutional websites. The searches followed the stages set out in the JBI Manual for Evidence Synthesis and the review protocol was registered with the OSF. A total of 85 documents were selected, involving ten FBCs. The maternal and neonatal outcomes described by the studies were categorized as follows: respect for women’s autonomy and needs; humanized evidenced-based care; feeling safe with and confident in care providers; use of integrative and complementary health practices; positive maternal experience and neonatal outcomes; and welcoming and comfortable environment. The findings reinforce that care delivery in FBCs is grounded in the biopsychosocial model of health care and that the physical environment and organization of these facilities and approach to childbirth are structured around the needs of pregnant people and their babies.
Social health determinants associated with mammography performance according to the 2013 and 2019 National Health Survey
Authors: Silva Denise Montenegro da , Cavalcante Yanka Alcântara , Oliveira Bruno Luciano Carneiro Alves de , Lopes Marcos Venícios de Oliveira , Fernandes Ana Fátima Carvalho , Pinheiro Ana Karina Bezerra , Aquino Priscila de Souza
Published: January 2025

Abstract Mammography is one of the main methods available for breast cancer screening in Brazil. However, differences in timely access and performance of the exam can be highlighted based on social determinants of health, considered relevant due to their influence on the health situation of a population. Thus, the present study aimed to identify the social determinants of health associated with access to and performance of mammography in Brazilian women. Cross-sectional and analytical study, based on secondary data from the National Health Survey (NHS) from 2013 and 2019 in Brazil. The main determinants of women who did not take the exam during the evaluated period were: aged 65 to 69 years, mixed race and black, living with more than three people, with incomplete primary education, in the 1st quintile of socioeconomic income, without health insurance, registered with the Family Health Strategy (FHS), and residents of the North and Northeast regions. There was a significant improvement in access to mammography exams in all states; however, structural factors, such as economic income, color, level of education, and age group were evident in why mammograms were not performed.