bluuebunny/crossref_metadata_2025 huggingface dataset:
Mulheres e moradia: despejos e remoções enquanto violências de gênero
Authors: Trotta Mariana , Castro Sobrinho Taiana de
Published: June 2024

O presente artigo tem por objetivo analisar o processo de feminização do déficit habitacional brasileiro, refletindo sobre a feminização da pobreza e a violência doméstica a partir das suas interconexões com a questão da moradia. Além disso, dedica-se a discutir o Protocolo para Julgamento com Perspectiva de Gênero, publicado pelo Conselho Nacional de Justiça em 2021, buscando avançar nas propostas no que se refere às ações possessórias, a fim de compreender esses conflitos também enquanto generificados. Por meio de uma abordagem feminista qualitativa, fundamentada em dados empíricos como índices sociais referentes aos direitos das mulheres no Brasil, bem como situada nos estudos de gênero, raça e classe, promovemos um olhar interseccional sobre os conflitos envolvendo a moradia urbana, que afetam de forma particular as mulheres, principalmente as mulheres negras e mães solo, que são a maioria no déficit habitacional. Assim, concluímos e defendemos que os despejos e as remoções forçadas, portanto, consistem em violências com acentuado recorte de gênero, especialmente para as mulheres negras e periféricas, expondo-as ainda a outros tipos de violações de direitos para além da moradia, em razão da sua condição de mulher.
As ações de benefícios previdenciários e assistenciais por incapacidade e o acesso à justiça à luz das alterações promovidas pela Lei n.º 14.331/2022
Authors: Melo Maria Izabel Rodrigues de
Published: June 2024

As alterações promovidas na Lei n.º 14.331 de 4 de maio de 2022 contemplaram significativas modificações, entre outros pontos, nos requisitos da petição inicial em causas previdenciárias relativas a benefícios assistenciais e por incapacidade. Sob a óptica do destinatário da norma, in casu, a pessoa requerente de benefício assistencial e a pessoa segurada da previdência social que pleiteia benefício por incapacidade, as alterações repercutem tanto na maneira de bater às portas do judiciário para reclamar pela concessão de tais benefícios como na própria posição de tais sujeitos no desenrolar do processo. O presente trabalho visa, a partir de pesquisa bibliográfica, analisar o conteúdo da norma que alterou os requisitos da petição inicial em causas previdenciárias referentes a benefícios assistenciais e por incapacidade e como, prima facie, tais alterações podem repercutir nos destinatários da norma, mormente no aspecto do acesso à justiça.
ATİNA'DA GÖÇMENLERİN HUKUKİ STATÜSÜ ÜZERİNE BİR İNCELEME: LYSIAS’IN ERATOSTHENES’E KARŞI ADLI SÖYLEVİ VE ÇEVİRİSİ
Authors: Yalazı Esra , Küçüker Sultan Deniz
Published: June 2024

Klasik Çağ’da Atina, siyasi ve hukuki varlığı bakımından bir yurttaşlar topluluğu olsa da kültürel ve ekonomik varlığını güçlendirmek için bünyesine kattığı büyük orandaki göçmen (metoikos) nüfusu ile çeşitlilik arz eden bir sosyolojik yapıya sahipti. Politik açıdan aktif olmayan bu göçmenler, Atina’da demokrasi ve oligarşi gerilimlerinin yaşandığı, kimi yurttaşların devletin varlığına adeta kastettiği tarihi dönem içinde, varlıklarının ve aslında sistemin de devamlılığının sağlanması açısından demokrasi siyasal düzeni tarafında duruş sergilemiş ve bizzat, devletin bekasından taraf olan diğer yurttaşlar ile birlikte direnişçiler arasında saf tutmuşlardı. MÖ 411 ile MÖ 404 tarihlerinde gerçekleşmiş olan iki büyük oligarşik devrim hareketinin en önemli tanıklarından biri, kendisi de Atina’da göçmen bir aileye mensup olan Hatip Lysias olmuştu. Lysias MÖ 404 yılında aralarında Eratosthenes'in de bulunduğu Otuzlar Hükümeti üyeleri tarafından tutuklanmış, tüm mallarına el konulmuş ve erkek kardeşi Polemarkhos bu süreçte Eratosthenes tarafından öldürülmüştü. Demokrasinin tekrar kurulmasının ardından (MÖ 403/2) yargılanmasına başlanan Eratosthenes’in davasına müdahil olan Lysias, Eratosthenes’e Karşı adlı söylevi ile sanığın, kardeşi Polemarkhos’un ölümünden sorumlu olduğunu kanıtlama ve onu bu işten mahkûm etme amacındadır. Bunu yaparken suçlamasını siyasal düzleme oturtarak genişleten hatip, hem Atina tarihinin bu en bunalımlı dönemi üzerine bir belge oluşturmuş hem de Atina’daki sistem üzerinden göçmenlik ve yurttaşlık üzerine tespit ettiği fikirlerle konunun her devirde tartışmaya açık olduğunu yalın bir dille ortaya koymuştur.
Child marriages - yesterday, today, tomorrow?
Authors: Kraljić Suzana
Published: June 2024

Child marriage is a formal or informal union involving a child or person under the age of 18. It is currently associated with violations of human rights, particularly the rights of children. The consequences of child marriage are long-term and relate to gender equality, health, and education, among others. Therefore, efforts are being made in national and international jurisdictions to eliminate harmful (traditional) practices. While individual countries have raised the marriageable age to 18, many still allow exceptions. Slovenia is one such example. In this article, the author analyzes the approach to the abolition of child marriage at the international and comparative law levels and is particularly critical of the current Slovenian regime.
Sexual abuse of minors in the catholic church: USA and Europe
Authors: Puskás Balázs
Published: June 2024

The year 2002 marked a pivotal moment in the American Catholic Church when a scandal erupted in Boston, unveiling a systemic crisis of clerical sexual abuse. This event unleashed a tidal wave of revelations that rippled through the Church, shattering the prevailing facade of "business as usual" and exposing a hidden stream of abuse that had flowed beneath the surface for decades. This paper examines the profound impact of the Boston scandal on the Catholic Church, both in the United States and in Europe.
This study delves into four reports from Europe and the United States, shedding light on the extent of the issue in each region. It aims to bridge a gap in the literature by providing a comprehensive analysis of these reports, emphasizing that the problem is not exclusive to the Church but is a societal issue. The examined reports reveal varying rates of abuse and abusers across countries, highlighting the need for a broader societal approach to combat child abuse.
This research underscores the importance of confronting the issue transparently and acknowledges the critical role played by independent investigations, such as the John Jay Report. The data from these reports are essential in dispelling misconceptions and fostering a fact-based understanding of clerical abuse.
In conclusion, this comparative analysis examines key findings from reports in the United States, France, Germany, and Ireland, highlighting both similarities and differences.
Topological Group Construction in Proximity and Descriptive Proximity Spaces
Authors: İs Melih
Published: June 2024

This paper introduces the topological group structure in proximity and especially descriptive proximity spaces, that is, the concepts of proximal group and descriptive proximal group are introduced. In addition, the concepts of homomorphism and isomorphism, which give important results in group theory, are discussed by interpreting the concepts of continuity in the theory of (descriptive) proximity
$\mathcal{D}$-Homothetic Deformations of Basic Classes of Almost Contact B-metric Structures
Authors: Aktay Şirin
Published: June 2024

We study $\mathcal{D}$-homothetic deformations of almost contact manifolds with B-metric.
Some basic classes are known to be invariant under these deformations. We examine the invariance of remaining basic classes. Also we investigate $\mathcal{D}$-homothetic deformations of normal and $K$-contact structures. We give examples of deformations of almost contact manifolds with B-metric structures in three dimensions.
Optimal Control Problem for Fourth-Order Bianchi Equation in Variable Exponent Sobolev Spaces
Authors: Özen Kemal
Published: June 2024

This work proposes a necessary and sufficient condition such as Pontryagin’s maximum principle for
an optimal control problem with distributed parameters, which is described by the fourth-order Bianchi equation involving coefficients in variable exponent Lebesgue spaces. The problem is studied by aid of a novel version of the increment method that essentially uses the concept of the adjoint equation of integral type.
On Level Hypersurfaces of the Vertical Lift of a Submersion
Authors: Yıldırım Mehmet , Özkan Ayşenur
Published: June 2024

Suppose that $(M,G)$ be a Riemannian manifold and $f:M\rightarrow \mathbb{R}$ be a submersion. Then, the vertical lift of $f,$ $f^{v}:TM\rightarrow \mathbb{R}$ defined by $f^{v}=f\circ \pi $ is also a submersion. This interesting case, differently from [10], leads us to investigation of the level hypersurfaces of $f^{v}$ in tangent bundle $TM$. In this paper we obtained some differential geometric relations between level hypersurfaces of $f$ and $f^{v}.$ In addition, we noticed that, unlike [13], a level
hypersurface of $f^{v}$ is always lightlike, i.e., it doesn't depend on any additional condition.
On Cayley Graphs with Constant Ricci Curvature
Authors: Dağlı Mehmet , Ünver Yonca
Published: June 2024

Understanding the geometry of graphs has become increasingly important. One approach utilizes the Ricci curvature introduced by Lin, Lu, and Yau, which offers a valuable isomorphism invariant for locally finite graphs. One of the key tools used in calculating curvatures is the matching condition. This paper exploits the matching condition to construct families of Cayley graphs exhibiting constant Ricci curvature.
Yüksekten Düşen bir Kedide Ağaç Dalı Tarafından Oluşturulmuş Abdomen ve Toraks Penetrasyon Yarası
Authors: Şensoy Baykan Sevda , Gün Akın Bahar , Aydın Kaya Didar
Published: June 2024

Yüksekten düşme sendromu çoğunlukla yılın sıcak aylarında görülmektedir. Bu vaka sunumunda yaşı bilinmeyen, melez ırk, yetişkin bir kedinin yüksekten düşme sonucunda abdomen ve toraks boşluğuna penetre olmuş bir dal parçasının oluşturduğu hasarlar ve operatif müdahalesi tanımlanmaktadır.
Sosyal Pazarlama Boyutuyla Sosyal Medya Mecralarında Özel Günlerde Yayınlanan Reklamların Marka İmajı Üzerindeki Etkisinin İncelenmesi
Authors: Çavuş Birol Furkan , Şahin Esen
Published: June 2024

Toplumlar tarih sahnesinde sürekli değişim ve gelişim içerisinde varlıklarını sürdürmüştür. Bu değişim ve gelişim çerçevesinde işletmeler de değer bileşenlerini ve tüketici ile olan ilişkilerini çağa ayak uydurarak yenilemiştir. Zamanla markalar klasik dönemlerdeki üretici ve alıcı ilişkisini terk etmiş ve daha toplum odaklı bir anlayışa yönelmiştir. Sosyal pazarlama, bu anlayışın bir sonucu olarak doğmuştur. Markaların, güçlü bir marka imajı ve sürdürülebilir bir başarı için topluma yönelik sorumluluklarını yerine getirmesi bir gerekliliktir. Sosyal pazarlama uygulamaları ile markalar bu sorumluluklarını yerine getirmekte, toplum nezdinde değer ve prestijlerini arttırmaktadır. Bu bağlamda çalışmanın amacı “Sosyal Pazarlama Boyutuyla Sosyal Medya Mecralarında Özel Günlerde Yayınlanan Reklamların Marka İmajı Üzerindeki Etkisinin İncelenmesidir.” Çalışmanın yöntem kısmında nitel araştırma tekniklerinden içerik analizi ve betimsel analiz kullanılmıştır. Çalışmanın örneklemi zaman ve maliyet gibi kısıtlar nedeniyle birçok özel gün içerisinden 8 Mart Dünya Kadınlar Günü özelinde yayınlanan reklamlar ile sınırlandırılmıştır. Araştırma sonucunda 8 Mart Dünya Kadınlar Günü özelinde yayınlanan reklamların tüketicilerde pozitif bir reaksiyon oluşturduğu sonucuna ulaşılmıştır. Tüketiciler, markaların kadına yönelik bu hassas tutumunu takdir etmiş ve sosyal medyada beğeni, yorum ve paylaşımlarla geniş kitlelere ulaşmasına aracılık etmiştir.
BİTKİSEL SÜT ÜRETİMİ VE İNSAN SAĞLIĞI ÜZERİNE ETKİSİ
Authors: Baba Gülçe , Bozatlı Sümeyye Betül , Dikici Abdullah
Published: June 2024

İnsan yaşamında doğumdan yaşlılığa kadar olan süreçte temel gıda maddesi olan süt önemli bir yere sahiptir. Ancak laktoz intoleransı, inek sütüne karşı alerji, vegan beslenme alışkanlığının artması, hayvansal süt üretiminin karbon salınımına katkısının yanı sıra bitkisel sütlerin düşük kalorili olması, kolesterol ve laktoz içermemesi, diyet lifi açısından zengin olması gibi beslenme yararları tüketicileri bitki bazlı süt alternatiflerine yönlendirmiştir. Bitkisel sütler tohumların, baklagillerin, tahılların süte benzeyen su özütleri olarak tanımlanmaktadır. İçeriğinde fenolik bileşikler, fitokimyasal maddeler, antioksidanlar, oligosakkaritler gibi insan sağlığı için son derece önemli bileşikleri bulundurmaktadırlar. Ancak bu ürünlerin yapı ve tekstür olarak inek sütüne benzemesi için bazı teknolojik aşamalardan geçmesi gerekmektedir. Bu teknolojik işlemlerin zaten gıda üretim sektöründe kullanılıyor olması bitkisel süt üretiminin avantajlarından birisidir. Bitki bazlı ürünler et, balık, süt, yumurta gibi geniş ürün yelpazesine sahiptir. Bu ürünler arasında Pazar payı en yüksek olan bitki bazlı sütlerdir. Yapılan çalışmalar sonucunda bitkisel süt sektörünün her geçen yıl büyümekte olduğu hatta 2016'dan 2022'ye kadar %13,3 oranında büyüme kaydetmesi beklenmektedir. Bu derlemede bitkisel sütlerin üretimi ve insan sağlığı üzerine etkileri konularında literatür verileri derlenmiştir.
Alfabetização geográfica na Educação Infantil: ausências na BNCC e suas interferências na aprendizagem da geografia
Authors: Nascimento Cláudia Pinheiro , Silva Francisco Thiago
Published: June 2024

A Geografia, bem como as demais ciências, devem ser trabalhadas desde a educação infantil, na busca da construção integral dos alunos. Dentro desta perspectiva surge a necessidade de se investigar como acontece o processo de alfabetização geográfica na educação infantil a partir das orientações da Base Nacional Comum Curricular (BNCC), no intuito de responder a seguinte questão principal: as ausências na BNCC referente ao processo de alfabetização geográfica interferem no processo de ensino aprendizagem da Geografia no ensino fundamental? E para isso, foi realizada uma pesquisa qualitativa, com base no estudo da BNCC que demonstrou, preliminarmente, que a mesma não preconiza nenhum processo de alfabetização de forma direta, nem tão pouco a geográfica, e que essa ausência traz consequências no processo de ensino-aprendizagem da Geografia no ensino fundamental.
RADIOTHERAPY 3D ISODOSEZONES GRAPHICAL OPTIMIZATION FOR HYPERFRACTIONATED TREATMENT PLANNING DOSIMETRY IN LUNG AND HEAD-NECK TUMORS WITH BIOLOGICAL EFFECTIVE DOSE MODEL
Authors:   PhD  Engineering, MSc  Physics-Mathematics, Physician. Independent Research Scientist. International  Association of  Advanced Materials, Sweden. UniScience Global Scientific Member, Wyoming, USA., Casesnoves Francisco
Published: June 2024

In recent lung and prostate cancer-radiotherapy contributions, [101-5], 3D imaging-processing Isodosezones [ Casesnoves, 2022 ], delimited by 3D Isodoselines were explained in lung cancer and other tumor types, such as prostate or lung. The radiotherapy model applied was the classical BED one algorithm. Modern biological-model-based Treatment Planning Optimization can get objective improvements by using Isodosezones/lines when selecting the optimal dose delivery/schedule for any personalized treatment. Improved programming, from [ Casesnoves, May 7th, 2024 ], and engineered software is perfectioned-developed for numerical hyperfractionated 3D TPO lung and head-neck cancer imaging-processing with upgraded previous database. Mathematical algorithms are explained-detailed. Developed programming patters and arrays are briefed. A series of imaging-processing graphics results obtained with the 3D Isodosezones Pareto-Multiobjective Optimization programming database are shown and explained in detailed. Applications in radiotherapy-oncology medical physics are subsequently briefed.
Factors Shaping Digital Learning Material Use in Primary Schools: An Exploratory Factor Analysis Approach
Authors:   Faculty of Primary Education, The University of Danang - University of Science and Education, Da Nang 550000, Viet Nam., Dinh Thuong T. N.
Published: June 2024

The utilization of digital learning materials in education, particularly in primary education, is becoming an increasingly prominent trend in the context of the Fourth Industrial Revolution. To assist teachers in adapting to these new educational trends, the strategic implementation of digital learning materials in schools plays a critical role in improving the teaching and learning processes. Despite the anticipated positive impact of digital learning material use on educational activities, significant challenges remain, including infrastructure issues, appropriate policies, digital content, support devices, support capabilities, and deployment capabilities in the digital environment, as well as human-related operational issues. The objective of this study is to explore the factors influencing teachers' use of digital learning materials in primary schools in the urban central of Vietnam. The validity and reliability of the “assessment of factors affecting the use of digital learning materials” instrument was examined using SPSS for exploratory factor analysis (EFA), to determine reliability and extract prominent factors. Through factor analysis employing Varimax rotation, 33 items were retained in the questionnaire. Analysis of the results from 129 respondents revealed four factors affecting the use of digital learning materials, with a KMO measure of sampling adequacy of 0.943 and Bartlett's test of sphericity indicating a Chi-Square with Sig value of 0.000 < 0.05. The findings suggest four groups of factors, providing guidance for teachers and students in identifying the key factors that enhance the effective use of digital learning materials in schools.
On Culture and Cultural Values
Authors:   PhD of Philosophy Student, University of Social Sciences and Humanities, Vietnam National University Ho Chi Minh City, Vietnam, Trang Nguyen Thi Ngoc
Published: June 2024

Culture is not merely a simple concept; it is a complex entity encompassing the creative products and activities of humanity. It is the result of continuous labor and innovation, passed down from generation to generation, reflecting the core values of truth, goodness, and beauty. Culture embodies both the spiritual and material expressions that humans have created and continue to create, ranging from works of art, architecture, language, and customs to systems of values, ideologies, and beliefs. In today’s context, as the world undergoes profound transformations in economics, politics, and technology, the role of culture has become more crucial than ever. Culture serves as a bridge that fosters understanding and respect among nations and civilizations, while also acting as a powerful tool to address global challenges and conflicts. The sustainable development of a nation cannot solely rely on economic or military strength but must also include cultural development. A prosperous society is one that values and nurtures its cultural heritage. This article will delve into the analysis of cultural values and its indispensable role in modern social life. We will explore how culture impacts various aspects of life, from social relations and education to individual and community development. Additionally, the article will discuss the challenges that culture faces in the digital and globalized era and how we can preserve and promote cultural values amidst the ever-changing landscape of the world.
Supervision System for Indonesia’s Government E-Procurement of Goods and Services
Authors:   Faculty of Law, Universitas Pembangunan Nasional Veteran Jakarta, Sugiyono Wardi, Heru , Winanti Atik ,   Faculty of Law, Universitas Pembangunan Nasional Veteran Jakarta
Published: June 2024

Using normative legal research with a statutory approach and a case approach, this research is prescriptive and analysed using descriptive qualitative methods after collecting data through the literature. In this research, Indonesia has entered the world of digital technology, including in terms of government procurement of goods and services. In order to reduce indications of Corruption, Collusion and Nepotism (KKN) in government, the procurement process for goods and services is carried out through electronic media. Ethics in the procurement of goods and services is good behaviour from all parties involved in the procurement process. The principles that need to be applied in the procurement of goods and services include efficiency, effectiveness, transparency, openness, competition, fairness/non-discrimination, and accountability. To fulfil this principle, a maximum supervision system is needed, so that there is a need for an electronic-based audit system to make it easier for inspection officials to carry out inspections in real time. Apart from that, the Business Competition Supervisory Commission is also one of the institutions authorized to maintain the stability of the procurement of goods and services in Indonesia.
Academic Stress: Comparative Study of Academic Stress of Class XII Students from Arts, Commerce and Science Streams
Authors:   Professor, Department of Psychology, Govt. M.G. College, Udaipur (Raj.), Chaudhary Dr. Ajay Kumar , Salvi Hemant ,   Research Scholar Dept. of Psychology Mohanlal Sukhadia University (Raj.), Detha Dr. Bhavna ,   Associate Professor, Subodh College, Jaipur (Raj.)
Published: June 2024

The present study was an attempt to make a comparative analysis of the academic stress of class XII students from the arts, commerce, and science streams. For this purpose, a total of 90 students from class XII were selected, out of which 30 were from the arts stream, 30 from the commerce stream, and 30 from the science stream. The Academic Stress Scale (ASS) by Poorva Jain and Neelam Dixit (2016) is used. This scale comprises 28 items that delve into various aspects of academic-related stressors and concerns, particularly those associated with the fear of academic failure. The findings of this study contribute to a better understanding of how academic stress varies across different streams, shedding light on potential factors that could be addressed to mitigate stress and enhance the overall well-being of Class XII students.
A clinical case of hypothyroidism with impaired higher cortical functions and anuria
Authors:   Burdenko Voronezh State Medical University, Polyanskaya Olga V. , Naidenko Anastasia A. ,   Burdenko Voronezh State Medical University, Terentev Pavel S. ,   Voronezh Regional Clinical Hospital of Emergency Medical Care No1
Published: June 2024

Relevance. A clinical case of hypothyroidism presenting with an unusual combination of symptoms is presented. Possible mechanisms for the development of the present clinical manifestations are reviewed, and the relationship to other disciplines is discussed. Aim and Objectives. To describe a clinical case in order to sensitize physicians to the neurologic manifestations of somatic diseases. Materials and methods. The patient was examined upon admission to the hospital, dynamic observation, and medical history was analyzed. Results. The presence in the patient of disorders of consciousness and higher cortical functions in combination with anuria and pronounced static and dynamic ataxia can be fully explained by decompensation of hypothyroidism. Conclusions. The presented clinical case demonstrates multisystemic manifestations of hypothyroidism; the patient's symptoms could require the attention of urologists, nephrologists, neurologists, therapists, and endocrinologists. The subacute onset of symptoms is important.
Rapidly progressive cerebellar syndrome as a manifestation of paraneoplastic brain damage. A case report
Authors:   Privolzhsky Research Medical University, Grigoryeva Vera N. , Ruina Ekaterina A. ,   Privolzhsky Research Medical University, Baranceva Yulia V. ,   Privolzhsky Research Medical University
Published: June 2024

Introduction. Rapidly progressive cerebellar syndrome (RPCS), previously referred to as “subacute cerebellar degeneration” or “paraneoplastic cerebellar degeneration”, is an autoimmune disorder, wich in the most cases is associated with a malignancy located outside the nervous system. RPCS is classified as one of the the paraneoplastic neurological syndromes and manifests in the early, often preclinical stages of oncopathology. Its diagnosis is difficult, but is necessary, since it can become a starting point for further screening for cancer. The article provides a clinical description of a 40-year-old patient with subacute development of hemiataxia and subsequent rapid progression of bilateral cerebellar deficiency associated with brainstem signs. The example of this case shows how difficult the diagnostic path is, since only the use of positron emission tomography and subsequent examination of a biopsy of the lesion in this patient made it possible to identify metastasis of poorly differentiated breast carcinoma in the axillary lymph node. The tumor itself was not found in the mammary gland. Since paraneoplastic antibodies were not detected in the patient’s blood and cerebrospinal fluid, a diagnosis of “probable” (not “definite”) RPCS was diagnosed in accordance with the diagnostic criteria proposed by the panel of experts in 2021. The treatment of cancer stopped progression of neurological deficit in the patient, but she remained severely disabled. Discussion. The approaches to the examination of patients with RPCS are discussed. Clinical assessment, neuronal antibodies testing and a targeted screening for cancer should be performed. Brief information is provided on the use of the PNS-Care scale in the diagnosis of paraneoplastic neurological syndromes. Conclusion. The presented case demonstrates the difficulties of diagnosing the RPCS and the associated cancer. The “definite” diagnosis of rapidly progressive cerebellar syndrome requires the presence of high or moderate risk antibodies and cancer that is consistent with the syndrome’s phenotype.
Clinical case of gastroesophageal reflux disease of the fourth degree
Authors:   Kursk State Medical University, Serezhkina Aleksandra V. , Khmelevskaya Irina G. ,   Kursk State Medical University, Razinkova Natalya S. ,   Kursk State Medical University, Zhiznevskaya Irina I. ,   Kursk State Medical University, Shistilina Galina V. ,   Kursk Regional Children's Clinical Hospital, Romanova Elizaveta A. ,   Kursk State Medical University
Published: June 2024

Gastroesophageal reflux disease not only has a wide variety of clinical manifestations from the digestive system, but also affects other systems associated with it. due to the fact that this disease can occur under the mask of others, it is difficult to say how much it is widespread. due to the fourth degree of the disease, which is one of the most severe, the child needs the advice of a surgeon who will choose the tactics of further treatment and subsequent rehabilitation. Preventive measures for this pathology include: do not resort to tight swaddling, keep the baby in an upright position after feeding.
Hypoxic-ischemic encephalopathy, intraventricular hemorrhage in the fetus and newborn
Authors:   Sechenov First Moscow State Medical University (Sechenov University), Balakina Aleksandra N. , Mokh Alina V. ,   Sechenov First Moscow State Medical University (Sechenov University), Polishchuk Albina R. ,   Sechenov First Moscow State Medical University (Sechenov University)
Published: June 2024

The article presents a clinical observation of a newborn with hypoxic-ischemic encephalopathy and intraventricular hemorrhage.
Practical guidelines on drug treatment of primary operable breast cancer
Authors:   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Lunkova Mariia N. , Litviakova Elena V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ivanov S.A. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology,   National Medical Research Center of Radiology, Kaprin A.D. ,   Patrice Lumumba Peoples' Friendship University of Russia,   National Medical Research Center of Radiology, Obninsk, Russia; Herzen Moscow Research Oncology Institute, Kiseleva Marina V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Denisov Maksim S. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology
Published: June 2024

Breast cancer (BC) treatment implies an integrated approach that involves inclusion of surgical techniques, radiation therapy, chemotherapy, endocrine therapy, targeted therapy, and in some cases immunotherapy in the treatment plan, while selection of treatment tactics depends on the tumor biological subtype, neoplastic process extension, and somatic status of the patient. The paper provides analysis of Russian clinical guidelines and advanced treatment regimens for primary operable BC that are based on the principle of case-by-case selection in each clinical situation considering the disease stage, tumor molecular subtype and the goals set by an expert specialist.
The use of high dose rate brachytherapy with Ir 192 in treatment of localized breast cancer
Authors:   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Litviakova Elena V. , Aminov G.G. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Denisov Maksim S. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ivanov S.A. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology,   National Medical Research Center of Radiology, Lunkova Mariia N. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Kiseleva Marina V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology
Published: June 2024

Thanks to the introduction of new screening programs, the emergence rate of novel anticancer drugs and the detection rate of early-stage breast cancer in Russia increase year by year. Organ preservation treatment, after which radiation therapy has to be performed, is the most common type of surgical treatment used in this cohort of patients. Today, various treatment methods are used, the most common is external beam radiation therapy, however, brachytherapy of breast cancer is also used.
Predictors of recurrent course of endometrial hyperplasia without atypia in women of reproductive age
Authors:   Patrice Lumumba Peoples' Friendship University of Russia, Orazov Mekan R. , Radzinskii Viktor E. ,   Patrice Lumumba Peoples' Friendship University of Russia, Khamoshina Marina B. ,   Patrice Lumumba Peoples' Friendship University of Russia, Mikhaleva Lyudmila M. ,   Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery, Mullina Irina A. ,   Patrice Lumumba Peoples' Friendship University of Russia, Artemenko Yuliia S. ,   Patrice Lumumba Peoples' Friendship University of Russia
Published: June 2024

Aim. To establish predictors of recurrent course of endometrial hyperplasia (EH) without atypia in women of reproductive age. Material and methods. A retrospective analysis of 180 patients of reproductive age was performed on the basis of the Department of Obstet-rics and Gynecology with a course of perinatology at the Patrice Lumumba Peoples' Friendship University of Russia in Semashko Clinical Hospital "RZD-Medicine" in 2020–2023. During the study, two cohorts of patients were formed depending on the course of EH: group 1 – the main group (n=95) was represented by patients with morphologically verified recurrent EH without atypia during a year of follow-up (1 or more episodes of relapse), group 2 – comparison (n=85) – patients with morphologically verified EH without a history of atypia, with no recurrence of hyperplasia during the year. The average age of patients in the studied cohort was 43±3.0 years (comparison groups – 40±2.0 years). Results. In a cohort of patients suffering from morphologically confirmed recurrent EH without atypia, a high incidence of the following predic-tors was established during the year: refusal/absence of medication in the anamnesis – 32.2%, duration of therapy (less than 6 months) – 23.2%, cyclic mode of progestogen use (from the 14th to the 26th day of menstrual cycle – MC/from 16 on the 26th day of the MC) – 15.8%. Patients with recurrent EH were significantly more likely to be obese in 45.3%, arterial hypertension – 38.9%, severe vitamin D deficiency – 32.6%, vitamin D deficiency – 40%, chronic endometritis – 41.1%. Conclusion. Predictors of recurrent course of EH without atypia in women of reproductive age are: refusal/absence of taking medication in anamnesis (odds ratio – OR 39.909; 95% confidence interval – CI 4.899–278.068), duration of therapy less than 6 months (OR 12.507; 95% CI 2.843–55.015), cyclic mode of progestogen use – from the 14th to the 26th day of the MC/from the 16th to the 26th day of the MC (OR 8.893; 95% CI 1.966–40.229). Patients with recurrent EH were significantly more likely to have severe vitamin D deficiency (OR 13.466; 95% CI 5.323–34.068), chronic endometritis (OR 4.237; 95% CI 2.032–8.833), hypertension (OR 3.881; 95% CI 1.858–8.801), obesity (OR 2.368; 95% CI 1.259–4.453), vitamin D deficiency (OR 1.574; 95% CI 0.814–3.045). Prevention of non-atypical hyperplasia with progestogens and lifestyle mod-ification carries a wide range of benefits, including those associated with a favorable fertility prognosis.
On the issue of differential diagnosis of primary vaginal leiomyosarcoma, benign metastatic leiomyoma with transformation of one node into leiomyosarcoma and primary peritoneal leiomyosarcoma
Authors:   Vladimirsky Moscow Regional Research Clinical Institute, Semenkov Alexey V. ,   Sechenov First Moscow State Medical University (Sechenov University), Setdikova Galiya R. ,   Vladimirsky Moscow Regional Research Clinical Institute, Yuriew Dmitriy Yu. ,   Vladimirsky Moscow Regional Research Clinical Institute, Stepanova Elena A. ,   Vladimirsky Moscow Regional Research Clinical Institute, Khitrov Nikolay V. ,   Vladimirsky Moscow Regional Research Clinical Institute
Published: June 2024

Differential diagnosis of primary leiomyosarcoma of the vagina/omentum, “benign metastatic leiomyoma” with transformation of one node into leiomyosarcoma, primary peritoneal leiomyosarcoma can present certain difficulties. Due to the rarity of peritoneal leiomyomatosis with malig-nant transformation in postmenopausal women, as well as the rarity of vaginal leiomyosarcomas, we present a clinical case of this kind of differ-ential diagnosis based on a pathohistological examination of material obtained during surgery in a woman with a giant pelvic mass.
Clinical Case A clinical case of severe hemorrhagic vasculitis
Authors:   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Filimonova Lyudmila A. , Zgura Julia A. ,   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Yaskevich Roman A. ,   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University,, Davydov Evgeny L. ,   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Rossovskaya Maria L. ,   Krasnoyarsk Interdistrict Clinical Hospital of Emergency Medical Care named after N.S. Karpovich, Delver Elena A. ,   Krasnoyarsk Interdistrict Clinical Hospital of Emergency Medical Care named after N.S. Karpovich, Kapustina Ekaterina V. ,   Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Published: June 2024

Diagnosis of systemic vasculitis often causes difficulties in clinical practice. A clinical case characterized by multiple organ and comorbid pathology is presented. The manifestation of intestinal bleeding was the reason for the diagnosis of severe ulcerative colitis. The appearance of a characteristic hemorrhagic rash, followed by renal pathology with hematuria and severe nephrotic syndrome, made it possible to establish the correct diagnosis.
Clinical case of progressive pulmonary mycobacteriosis with potential genetic predisposition in a patient with mild bronchial asthma
Authors:   Central Research Institute of Tuberculosis, Makariantz Natalia N. ,   Patrice Lumumba Peoples' Friendship University of Russia, Karnaushkina Maria A. ,   Patrice Lumumba Peoples' Friendship University of Russia, Salamaikina Svetlana A. ,   Central Research Institute of Epidemiology, Mironov Konstantin O. ,   Central Research Institute of Epidemiology, Babak Sergey L. ,   Yevdokimov Moscow State University of Medicine and Dentistry, Strutynskaya Anastasia D. ,   Patrice Lumumba Peoples' Friendship University of Russia
Published: June 2024

Mycobacteriosis is an infectious disease caused by opportunistic non-tuberculous microbacteria in patients with chronic respiratory pathology and decreased immunological reactivity. The number of patients with this pathology is increasing not only in Russia, but throughout the world. Scientists' attention was drawn to the fact that the isolation of non-tuberculous mycobacteria from patient’s sputum samples does not correlate with the incidence of non-tuberculous mycobacteriosis and the need for its treatment. This may be due to the presence of gene polymorphisms that affect the structure and functional characteristics of innate immune factors. The article presents a rare clinical case of non-tuberculous mycobacteriosis caused by Mycobacterium avium in a 50-year-old woman without severe concomitant diseases and secondary immunodeficiency. The genetic study revealed polymorphic gene alleles, which may predispose this patient for the infection and severe course of this disease.
Infectious diseases transmitted with milk: literature review
Authors:   Pirogov Russian National Research Medical University, Skryabina Anna A. , Kladnitskaya Anastasiya D. ,   Pirogov Russian National Research Medical University, Shakhmardanov Murad Z. ,   Pirogov Russian National Research Medical University
Published: June 2024

Milk is an excellent nutrient medium in which most saprophytic bacteria and pathogenic microbes grow well under certain conditions. Contamination of milk substrates by microbial pathogens is the cause of the spread of infectious diseases not only from the group of intestinal infections, but also infections with multiple mechanisms of pathogen transmission. Widespread consumption of milk determines the ubiquitination of infectious diseases, in which this product can serve as a factor of pathogen transmission. About 4% of infectious diseases worldwide are associated with milk consumption. The sources of infection are, as a rule, dairy animals, which are the reservoir of pathogens; the factors contributing to the contamination of milk with pathogenic and opportunistic pathogens are technological and sanitary-hygienic violations in the production, storage and sale of dairy products. Despite the fact that the route of transmission of infections with milk is widespread, it is the most underestimated among other intestinal infections. To date, there are no simple and rapid tests to detect the presence of pathogens such as Brucella spp., Coxiella burnetii, Salmonella typhimurium, Campylobacter spp. in milk, the invention of which could significantly reduce the burden of milkborne diseases. This review discusses the epidemiologic importance of milk and milk products in the spread of infectious diseases and possible areas of prevention.
Phenotypes of chronic inflammatory demyelinating polyneuropathies with manifestation after coronavirus infection COVID-19
Authors:   Pavlov First Saint Petersburg State Medical University, Kushnir Yana B. , Bezvodinskikh Alexander I. ,   Pavlov First Saint Petersburg State Medical University, Vladykina Anastasia V. ,   Pavlov First Saint Petersburg State Medical University, Totolyan Natalia A. ,   Pavlov First Saint Petersburg State Medical University
Published: June 2024

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an orphan disease of the peripheral nervous system. The clinical phenotypes of CIDP may influence the choice of primary pathogenetic therapy. In some cases, viral infection may be a trigger for the development of an immune-mediated process. The role of coronavirus infection (COVID-19) as a trigger of the clinical manifestation of CIDP, as well as the impact of COVID-19 on the disease course and response to pathogenetic therapy remains an unexplored issue. The paper presents a series of clinical cases CIDP with manifestations after COVID-19 infection and review of publications.
Modern approaches to the diagnosis and treatment of functional neurological disorders: clinical case and literature review
Authors:   Sechenov First Moscow State Medical University (Sechenov University), Petelin Dmitry S. , Ragimova Aynur A. ,   National Research University Higher School of Economics,   Research center of neurology, Gizetdinova Kamilya R. ,   Kazan Federal University, Viazmin Alexandr O. ,   National Research University Higher School of Economics, Borisenko Egor A. ,   Sechenov First Moscow State Medical University (Sechenov University), Volel Beatrice A. ,   Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; Mental health research center
Published: June 2024

Functional neurological disorders are widely represented in clinical practice, but their etiology, pathogenesis, as well as approaches to diagnosis and therapy have not been sufficiently studied. This article provides an overview of the taxonomy and clinical manifestations of functional neurological disorders. Modern data on the diagnosis of the discussed group of disorders are also presented, with an emphasis on instrumental methods – electroencephalography, transcranial magnetic stimulation, functional magnetic resonance imaging. The available data on evidence-based approaches to the treatment of functional neurological disorders are summarized. The main points of the literature review are illustrated by clinical observation.
Ortaokul Peygamberimizin Hayatı Ders Kitaplarının Kök Değerler Açısından İncelenmesi
Authors: Yıldız Mehmet
Published: June 2024

Değerler eğitiminin yapıldığı ortamlardan biri okuldur. Türkiye’de uygulanan eğitim sistemi, akademik açıdan başarılı olmanın yanı sıra, temel değerleri benimseyen bireyler yetiştirmeyi de hedeflemektedir. Bu hedefe ulaşmak için, akademik eğitimle bir arada yürütülen sistemli bir değerler eğitimine ihtiyaç vardır. Ülkemizde hâlihazırda uygulanan eğitim programları bu işlevi yerine getirebilecek şekilde oluşturulmuş ve okulda öğrencilere kazandırılmak üzere on kök değer belirlenmiştir. Bu değerler adalet, dostluk, dürüstlük, öz denetim, sabır, saygı, sevgi, sorumluluk, vatanseverlik ve yardımseverliktir. Türk Milli Eğitimi’nin temel amaçları doğrultusunda belirlenen bu değerler, okulda yer alan tüm derslerin öğretim programlarına ve ders kitaplarına yansıtılmıştır. Bu çalışmada ortaokullarda seçmeli, imam hatip ortaokullarında zorunlu dersler arasında yer alan Peygamberimizin Hayatı dersi için hazırlanmış olan ders kitapları, kök değerler açısından incelenmiştir. Çalışmanın temel amacı Peygamberimizin Hayatı (5-8) ders kitaplarında kök değerlerin ne ölçüde yer aldığını tespit etmektir. Bu amaç çerçevesinde çalışmada aşağıdaki sorular cevaplandırılmaya çalışılmıştır: 1. Ortaokul Peygamberimizin Hayatı ders kitaplarında hangi kök değerler yer almaktadır? 2. Ortaokul Pey-gamberimizin Hayatı ders kitaplarında kök değerlerin yer alma sıklık ve oranları nedir? 3. Ortaokul Peygamberimizin Hayatı ders kitaplarında yer alan kök değerlerin sınıf düzeylerine göre dağılımı nasıldır? Çalışma nitel türde ve eğitim alanındaki araştırmalarda en çok kullanılan tarama modelindedir. Çalışmanın verileri doküman incelemesi tekniği ile elde edilmiştir. Çalışmanın verileri 2022-2023 eğitim-öğretim yılında ortaokul ve imam hatip ortaokullarında okutulan Peygamberimizin Hayatı ders kitaplarından elde edilmiştir. Ders kitapları incelenirken, dersin öğretim programında belirtilen kök değerler ve bu değerlerle ilişkili olan tutum ve davranışlar dikkate alınmıştır. Toplanan verilerin çözümlenmesi, nitel araştırmalarda kullanılan betimsel analiz yaklaşımıyla yapılmıştır. Ders kitaplarında yer alan kök değerlerin sınıf düzeyine göre dağılımı, sayfa numaraları ve frekans değerleri belirtilerek tablo haline getirilmiştir. Bulguları desteklemek amacıyla, her bir kök değerin en az ve en çok yer aldığı ders kitabından ilgili değeri yansıtan alıntılara yer verilmiştir. Araştırma sonuçlarına göre programda belirtilen kök değerler, her sınıf düzeyinin ders kitabında yer almaktadır. Ders kitaplarında en çok yer alan kök değer sevgi, en az yer alan kök değer ise öz denetimdir. Kök değerlerin her sınıf düzeyinin ders kitabında yer alması, programda öngörülen değerler eğitimi anlayışıyla uyuşmaktadır. Ders kitaplarında kök değerlere genellikle konu metinlerinde, okuma metinlerinde, etkinliklerde ve görsel açıklamalarda temas edilmiştir. Peygamberimizin Hayatı (5-8) ders kitaplarının kök değerler açısından zengin bir içeriğe sahip olduğu söylenebilir.
Effects of atmospheric pollution on human health in Port Harcourt: Its implication on urban planning
Authors: Eyetan Tega Emmanuel , Ifuwe Christabel Chineme
Published: June 2024

This study examined the health implication of atmospheric pollution in Port Harcourt. The study adopted both experimental research design and ex-post facto designs. This involved direct field measurements of air pollutants (Sulphur (IV) Oxide, Nitrogen Oxide, Carbon Monoxide, and PM10) and archival medical data of air borne diseases in Port Harcourt. The study area was stratified into four zones using existing land use types. In each of the four zones, three most heavily congested traffic intersections were selected for monitoring the air pollutants. The data generated were analysed using multiple regression statistical tool at 0.05 level of significance. The study revealed that the concentration of air pollutants measured in parts per million for SO2 (0.24), NO2 (0.06), CO (33.1) and PM10 (2.65) in Port Harcourt metropolis exceeded WHO standards for SO2 (±0.00-0.01), NO2 (±0.03-0.06), CO (±3-10) and PM10 (±0.9-1.12). The study revealed that air borne diseases were on the increase in Port Harcourt metropolis. During the rainy season, there was a low prevalence of Air borne diseases in Port Harcourt and this could be attributed to the rainfall which reduces dust and fine particles. At F values of 8.59 and 10.871 respectively, SO2, and PM10 had a significant effect on the occurrence of air borne diseases in Port Harcourt metropolis at P<0.05. As such, SO2, and PM10 gases were responsible for the increase in cardiovascular diseases, reduced lung function, asthma, irritation of the eyes, cough, nausea in Port Harcourt metropolis. To mitigate the effects of atmospheric pollution on human health, urban planning strategies should focus on promoting sustainable transportation options (such as public transit, cycling, and walking), increasing green spaces and planting trees to improve air quality, promoting energy-efficient buildings, and implementing regulations to reduce emissions from industrial sources. Incorporating measures to improve air quality into urban planning decisions can help create healthier and more livable cities for residents.