bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-layer Hybrid Classification Model of COVID-19 Chest X-ray Images v1
Authors: Poomkur Thanakorn
Published: October 2021

The coronavirus disease of 2019(COVID-19) has been declared a pandemic and has raised worldwide concern. Lung inflammation and respiratory failure are commonly observed in moderate-to-severe cases. Radiography or chest X-ray imaging is compulsory for diagnosis, and interpretation is commonly performed by skilled medical specialists. In this study, we propose anew computer-aided diagnosis (CADx) tool for identifying chest X-ray images of COVID-19 infection using a multi-layer hybrid classification model (MLHC). The MLHC-COVID-19 consists of two layers, Layer I: Healthy and non-Healthy; Layer II: COVID-19 and non-COVID-19. The MLHC-COVID-19 was evaluated in real COVID-19 cases. The classification results showed promising performance comparable with other existing techniques considering the accuracy, sensitivity, and specificity of 96.20%, 96.20%, and 0.971%, respectively. This demonstrates the effectiveness of the MLHC-COVID-19 in classifying chest X-ray images, enhancing the accuracy of chest X-ray image interpretation with a reduction in the interpretation time. Furthermore, a detailed comparison of the MLHC-COVID-19 with other techniques has been presented.
SNARE-seq2 v3
Authors: Plongthongkum Nongluk , H Diep Dinh , Chen Song , Lake Blue , Zhang Kun
Published: October 2021

To study the heterogeneity of complex tissues by joint profiling of gene expression and its regulation, we require an accurate and high-throughput method. Here we described improved high-throughput combinatorial indexing-based single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-Seq2) co-assay. This protocol involves fixing and permeabilizing the nucleus followed by tagmentation, chromatin barcode ligation, reverse transcription, pooling and splitting for the next rounds of cell barcode ligation into cDNA and accessible chromatin (AC) on the same nucleus. The captured cDNA and AC are co-amplified before splitting and enrichment into single-nucleus RNA and single-nucleus AC sequencing libraries. The protocol can also be applied to both nuclei and whole cells to capture mRNA in the cytoplasm. This improvement allows us to generate hundreds of thousands of data set of each assay and can be scaled up to half a million cells from a single experiment. The entire procedure can be complete in 3.5 d for generating joint single-nucleus RNA and single-nucleus ATAC sequencing libraries.
The Saqqa-khaneh Calligraphy-Painting Movement in Iran
Authors: Zakeri Saeid
Published: October 2021

This article aims to describe the Saqqa-khaneh calligraphy-painting movement in Iran. This School was a significant movement in modern Iranian art that became influential in the formation of a modern approach toward prevailing traditional heritage. This artistic movement came about in the midst of the country’s modernisation, in an endeavour to link traditional Iranian culture with contemporary aspects of the visual arts, and with contemporary western paintings in particular. Abiding by Iranian tradition was not the primary engine driving Saqqa-khaneh art, nor was it to emulate western art. Contemporary Iranian artists have enriched Persian script endowing it with variety and aesthetic intention and have produced many masterpieces, particularly when calligraphy is combined with pictorial language. In the last six decades, this movement has gained a nation-wide significance in contemporary Iranian society and culture, leading to an increasing number of practitioners, collectors and a presence of calligraphy-painting-inspired advertising and design. Moreover, it has gradually found a position in the global art world. In the current art market, Persian contemporary calligraphy-painting stands out among Middle-Eastern productions.
Gender in the Climate-Conflict Nexus: “Forgotten” Variables, Alternative Securities, and Hidden Power Dimensions
Authors: Ide Tobias , Ensor Marisa O. , Le Masson Virginie , Kozak Susanne
Published: October 2021

The literature on the security implications of climate change, and in particular on potential climate-conflict linkages, is burgeoning. Up until now, gender considerations have only played a marginal role in this research area. This is despite growing awareness of intersections between protecting women’s rights, building peace and security, and addressing environmental changes. This article advances the claim that adopting a gender perspective is integral for understanding the conflict implications of climate change. We substantiate this claim via three main points. First, gender is an essential, yet insufficiently considered intervening variable between climate change and conflict. Gender roles and identities as well as gendered power structures are important in facilitating or preventing climate-related conflicts. Second, climate change does affect armed conflicts and social unrest, but a gender perspective alters and expands the notion of what conflict can look like, and whose security is at stake. Such a perspective supports research inquiries that are grounded in everyday risks and that document alternative experiences of insecurity. Third, gender-differentiated vulnerabilities to both climate change and conflict stem from inequities within local power structures and socio-cultural norms and practices, including those related to social reproductive labor. Recognition of these power dynamics is key to understanding and promoting resilience to conflict and climate change. The overall lessons drawn for these three arguments is that gender concerns need to move center stage in future research and policy on climate change and conflicts.
Comprehensive Security: The Opportunities and Challenges of Incorporating Environmental Threats in Security Policy
Authors: Räisänen Helmi , Hakala Emma , Eronen Jussi T. , Hukkinen Janne I. , Virtanen Mikko J.
Published: October 2021

In security and foreign policy discourse, environmental issues have been discussed increasingly as security threats that require immediate action. Yet, as the traditional security sector does not provide straightforward means to deal with climate change and other environmental issues, this has prompted concerns over undue securitisation and ill-placed extreme measures. We argue that an effective policy to address foreseeable environmental security threats can only be developed and maintained by ensuring that it remains resolutely within the domain of civil society. In this article, we consider the case of Finland, where the policy concept of comprehensive security has been presented as the official guideline for security and preparedness activities in different sectors. Comprehensive security aims to safeguard the vital functions of society through cooperation between authorities, business operators, organisations, and citizens. We analyse the opportunities and challenges of Finland’s comprehensive security policy in addressing environmental changes through a three-level framework of local, geopolitical and structural security impacts. Our empirical evidence is based on a set of expert interviews (n = 40) that represent a wide range of fields relevant to unconventional security issues. We find that the Finnish comprehensive security model provides an example of a wide and inclusive perspective to security which would allow for taking into account environmental security concerns. However, due to major challenges in the implementation of the model, it does not fully incorporate the long-term, cross-sectoral, and cascading aspects of environmental threats. This weakens Finland’s preparedness against climate change which currently poses some of the most urgent environmental security problems.
Diglosia ya instrucción del mirandés y del asturianu. Semeyances y diverxencies discursives ente Vasconcelos y los autores de la xeneración asturiana del folclor (1880)
Authors: Rodríguez Álvarez Marcos
Published: October 2021

A lo cabero del sieglu XIX garra puxu l’interés filolóxicu poles llingües mirandesa y asturiana, con Vasconcelos como referente nel ámbitu mirandés y dellos miembros de la xeneración del folclor, venceyaos al grupu d’estudios culturales La Quintana, ente los principales estudiosos del asturianu. Ún y otros van coincidir n’identificar los sos respeutivos contestos como realidaes llingüístiques desequilibraes, anque plantegando sobre les mesmes análisis y visiones estremaes. Mentanto Vasconcelos pescuda nos fautores de calter socio-hestóricu que s’atopen tres del retrocesu social de la llingua mirandesa, solliñando ente ellos l’aición de la instrucción primaria, los folcloristes asturianos, llantaos na perspeutiva dialeutizante qu’heredaben de les xeneraciones intelectuales anteriores, valdránse del prexuiciu llingüísticu hacia l’asturianu pa xustificar como natural la situación desequilibrada d’ésti énte’l castellanu, qu’identifiquen como idioma de progresu. Mesmo Vasconcelos que los miembros de la xeneración del foclor van a emponderar l’interés del estudiu eruditu de les sos respeutives llingües d’atención pol so valir como ayalgues filolóxiques y como mediu p’afondar na meyor conocencia, respeutivamente, del portugués y del castellanu; pero mentanto que Vasconcelos vindica la presencia del mirandés nel enseñu primariu col envís de caltener viva esta fala, los folcloristes asturianos guarden nel so tarrén silenciu a esti respeutive.
Testamentos bercianos del sieglu XIV
Authors: Sánchez González de Herrero Mª Nieves
Published: October 2021

Esti trabayu revisa delles carauterístiques llingüístiques de diez documentos del sieglu XIV del fondu del monesteriu de San Andrés d’Espinareda (Lleón). L’asitiamientu del monesteriu n’El Bierzu occidental apurre l’interés d’ufiertar una variedá asitiada nel continuu norteñu peninsular en frontera llingüística ente’l gallegu y l’asturianolleonés occidental. Los testimonios seleicionaos son seis cartes de testamentu, dos donaciones post mortem, una iguadura de donación y una donación que recueye les voluntaes de l’anterior dueña de lo donao; ye dicir, tienen en común que recueyen les caberes voluntaes de los titulares. L’análisis céntrase principalmente nel léxicu, pero espónense tamién dalgunos de los rasgos llingüísticos presentes nos fragmentos seleicionaos. Trátase d’un análisis descriptivu y comparativu nel que se busca’l significáu de les voces y la so presencia, o non, en fontes y corpus medievales d’otres estayes peninsulares, sobre manera gallegos, asturianos y lleoneses.
Onde sal fumu ye qu’hai fueu. Paremias populares pronunciadas por don Quijote en las traducciones integrales rumanas y asturiana
Authors: Fontana i Tous Jon
Published: October 2021

Tomando como corpus d’estudiu les 86 paremies populares pronunciaes por don Quixote a lo llargo de la obra maestra cervantina (24 na primer parte y 62 na segunda), analizaremos qué estratexes traductolóxiques s’emplegaron nes versiones integrales qu’esisten n’asturianu (Suárez, 2015) y en rumanu (Frunzetti & Papu, 1965; Mărculescu, 2005). Con esi envís, aplicaremos al mentáu corpus los criterios metodolóxicos asoleyaos na nuesa tesis «Algo va de Stan a Pedro. Parèmies populars a les traduccions romaneses integrals del Quijote» (2014), onde s’afita una nidia estremación ente les «equivalencies» (cuando’l traductor ye a atopar un refrán xenuín con sentíu semeyu) y los «anosamientos» (cuando’l traductor se manda d’otros recursos: traducir el refrán lliteralmente, glosalu o bien aplica-y a la versión daqué traza parémica). L’artículu complétase con un estimable apéndiz que presenta’l corpus estudiáu, ye dicir, los 86 refranes orixinales del Quijote, acompangaos de les correspondientes traducciones asturiana y rumana, ensin escaecer les destremaes notes esplicatives que los traductores amestaron a les sos respeutives versiones.
Environment and women's reproductive health
Authors: Ailamazyan Eduard K.
Published: October 2021

For more than 40 years Scientific Research Institute of Obstetrics and Gynecology named after V.I. D.O. Otta RAMS is the leading institution for the problem "Ecology and reproductive health of women" of the Scientific Council (NS) for Obstetrics and Gynecology of the RAMS and the Ministry of Health of the Russian Federation (M3 RF)
Ecological genetics, reproductive health and predictive medicine
Authors: Baranov Vladislav S.
Published: October 2021

Ecological genetics plays a major role in protecting reproductive health and prevention of inherited and inborn disorders. Protection of reproductive health in women poses special problems as because of long period of oogenesis damaging of female gametes is feasible during several successive generations. Recent achievements in predictive (preventive) medicine render opportunities for presymptomatic diagnostics and efficient prevention of inherited and inborn disorders as well as severe and common diseases in postnatal life. Testing of genetic polymorphisms creates solid genetic background in predictive medicine. Thorough studies are needed to evaluate predictive value of already existing genetic tests. Necessities for solid legislative background and comprehensible medical evaluation of genetic tests results are also quite urgent tasks of current medicine. Widespread population genetic testing with subsequent relevant interpretation of the results might pave the way for more objective evaluation of unfavorable action of ecological factors in humans. These studies in conjunction with already elaborated Genetic Chart of Reproductive Health might help a lot in protecting of reproductive health as well as in prevention of inherited and inborn disorders.
Experimental study of mechanisms of disturbances of hypothalamic regulation of reproduction
Authors: Arutjunyan A. V. , Kerkeshko G. О. , Stepanov М. G. , Korenevsky А. V. , Ailamazyan Е. К.
Published: October 2021

Summary: Diurnal rhythms of the activity of a number of monoaminergic systems of the hypothalamus (norepinephrine and serotonin in PA and ME-ArN, as well as dopamine in ME-ArN) have been shown to depend on the functioning of an endogenous circadian oscillator in SCN of the hypothalamus. Light modifies the diurnal rhythms of the neurotransmitters. Enhancement of the activity of the noradrenergic systems with sex steroids in proestrus is an important mechanism of the forming of the preovulatory surge of GnRH and gonadotropines secretion, which initiates ovulation. Consideration of our own experimental data and literature allow the supposition that the change of diurnal rhythms of norepinephrine in PA and ME-ArN could result in profound disturbances of hypothalamic regulation of reproductive cycles and be one of key reasons for negative effect of xenobiotics on reproduction.

Supported by RFBR grant 04-04-49204.
Dmitry Oscarovich Отт and his contribution то obstetrics and gynaecology (to 150 birth anniversary)
Authors: Ailamazyan Е. К. , Tsvelev U. V. , Bezhenar' V. F. , Yakovenko Т. G.
Published: October 2021

Summary: In current article, devoted to 150 birth anniversary of famous russian obstetrician-gynaecologist Dmitry Oscarovich Ott, main directions of his scientific work are described: operative gynaecology (invention of ventoscopy and vaginal surgery), neuroendocrinal regulation of specific female functions, infusion therapy in obstetrics. Based on professor Otts school representatives are depicted: V.V. Stroganov, L.I. Bublichenko, V.V. Preobrajensky, R.G. Lurie, V.A. Polubinsky, R.V. Kiparsky, A.E. Mandelshtam and others.
Free radical reactions in the development of combined hyperplastic processes in female reproductive system organs
Authors: Niauri D. A. , Chepur S. V. , Popov Е. N. , Charitonov К. P. , Kuznetsova I. V.
Published: October 2021

Intact myometrium specimen, received from 56 women of reproductive age during surgical interventions. There were 30 women with combined hyperplastic processes in the reproductive system organs (uterine myoma, endometrium hyperplasia, adenomyosis, benign ovarian tumors, mastopathy, background cervical pathology), and in 26 cases solitary uterine myoma was found. At infrared spectrometry of the lyofilized myometrium, taken from patients with combined proliferation foci, a stable peak with wave number 3500 sm1 was found, which reflects the accumulation of molecules with oxidized OHgroups and a change in proportion of OH/NHcontaining molecules. At the study of the myometrium of patients with single myoma focus the described peak was absent. The acquired data suggests, that combined benign hyperplasias in the reproductive system organs are accompanied by the oxidative stress cascade reactions, characterized by uncontrollable production of free radicals and/or insufficiency of antiradical protection mechanisms.
The negative experience of somatostatin synthetic analogist using in therapy of policystoc ovaries
Authors: Grinvald D. V. , Kirsanov А. A. , Kasumova А. R. , Bondarenko М. V.
Published: October 2021

The blood content of insulinlike growth factor1 (IGF1) in woman with ovarian hyperstimulation syndrome (OHSS) is low that may be connect with damage of synthetic function of liver. The use of synthetic analogist of somatostatin in treatment of OHSS dont lead to reliable positive results. Low content of IGF1 in OHSS makes pathogeneticaly nonjustifight the treatment of OHSS by synthetic analogist of somatostatin.
Comparison of the effectiveness of two- and three-phase regimens of replacement, hormonal therapy in climacteric syndrome in perimenopause
Authors: Shapovalova К. A. , Tarasova М. A.
Published: October 2021

Climacteric syndrom is one of the most frequent complains among females in perimenopausal period that leads to significant deterioration of health. Complex of syptoms vegetovascular, neuropsychick, trophic disorders and menstrual disorders is caused by age process of steroidogenesis. The use of combined estrogenhestagen medicine in perimenopausal period is proved pathogenetically, however every fith woman has climacteric disorders during the breakes of taking twophase replacable medicine. In this case, it is reasonable to take three phase replacable medicine, that contain changeable dosage of estrogens throughout the whole period of treatment.
Nucleic acid sequence—based amplification (nasba) and its application in obstetrical and gynecological practice
Authors: Shipitsyna Е. V. , Budilovskaya О. V. , Savitcheva А. М.
Published: October 2021

Method of isothermal amplification of nucleic acids NASBA {Nucleic Acid SequenceBased Amplification) is becoming widely used in diagnostic molecular microbiology including diagnostics of infections in pregnant women and newborn infants. NASBA method possesses the unique ability to amplify RNA target selectively in the presence of DNA target of identical sequence, which determines its main application areas: diagnosis of RNA viruses, investigation of bacterial and viral gene expression, diagnosis of bacterial infections based on 16S rRNA detection. In the article the principle and the main steps of the method as well as some applications in diagnostic microbiology are reviewed. In addition, a comparative evaluation of NASBA and other amplification techniques such as polymerase chain reaction (PCR) and reversetranscriptase PCR (RTPCR) is presented.
Pregnancy and childbirth in a patient with spinal muscular atrophy
Authors: Novikov В. N. , Sokolov К. A. , Smolina М. S. , Vakharlovsky V. G.
Published: October 2021

A pregnancy and labour description is given for a 1st group disabled person suffering from the genetically confirmed spinal muscular atrophy type II (SMA type II). Statistically, the risk for the infant being born with SMA is less then 0,5 %. No serious complications were identified during the pregnancy; the Caesarean section was performed during the delivery. Considering the substantial atrophy of the muscular system, myorelaxants were excluded during the followed anaesthesia. A male infant was extracted without genetic pathologies, weighting 1900 g, 40 cm long, scored 7/7 by the Apgar scale. State social and community organizations provided aid in caring for the baby.
The evaluation of uterine arteries embolization value in functional surgery in patients with uterine myoma
Authors: Daye М. М. , Niauri D. A. , Ryjkov V. К. , Sergeeva I. V.
Published: October 2021

The experience of constant embolization of uterine arteries (60 patients) has shown that constant intravascular occlusion of uterine arteries in some cases may be considered as rational intervention and an alternative for organ-saved surgery. Temporary embolization of uterine arteries (20 patients) orientated to decreasing of intraoperative bleeding risk allows to perform reconstructive-plastic uterine surgery in optimal condititons.
The content of vascular endothelial growth factor in the dynamics of pregnancy complicated by preeclampsia
Authors: Patsaev Т. A.
Published: October 2021

The level of vascular-endothelial growth factor (VEGF) were investigated at physiological pregnancy and in dynamics at preeclamptic pregnancy. It was found out that VEGF levels were lower in preeclampsia group beginning 16 weeks of gestation.
sepsis; Systemic Inflammatory Response Syndrome (SIRS); obstetrics; maternal mortality
Authors: Repinа М. A.
Published: October 2021

A retrospective review of material deaths from sepsis in Saint-Petersburg was undertaken for the period 1996- 2004. Maternal mortality ratios from sepsis for that period 12.4 per 100000 live birth. Conclude made, that the treatment of patiens with sepsis during pregnancy or puerperium should be much more intensive.
Professor gubarev а.р. (dedicated for his 150th anniversary)
Authors: Tsvelev Y. V.
Published: October 2021

The article is dedicated for famous obstetrician - Gubarev Alexander
Heterogeneous Properties of Locus Coeruleus Cortical Projection Neurons
Authors:   , Chandler Daniel John , Waterhouse Barry D.
Published: October 2021

The brainstem nucleus locus coeruleus (LC) innervates the entire central nervous system and is the primary source of norepinephrine (NE) to the neocortex. While classically considered a homogenous modulator of forebrain activity by virtue of highly widespread and divergent axons, recent behavioral and pharmacological evidence suggest this nucleus may execute distinct operations within functionally distinct cortical regions. To test the hypothesis that LC is more functionally organized than previously recognized, we compared the distributions of neurons in LC projecting to orbitofrontal (OFC), medial prefrontal (mPFC), anterior cingulate cortices (ACC) to those projecting to primary motor cortex (M1) through a variety of anatomical, molecular, and electrophysiological assays. Here we show that each of these cortical regions is innervated by a distinct subset of LC neurons with minimal overlap between groups. Moreover, cells projecting to OFC and mPFC were found to contain enriched mRNAs related to synaptic excitability and transmission relative to those innervating M1. Finally, through the use of whole cell patch clamp, we demonstrate that these same populations of cells are characterized by a greater level of spontaneous tonic discharge. This set of studies is the first to identify such unique molecular and physiological properties within subsets of terminal field-specific LC neurons and supports the idea that LC projections to the neocortex are organized according to the functional role of their target circuitry. Such an arrangement may have behavioral significance insofar as PFC projection neurons have lower thresholds of activation and higher basal discharge rates than M1 projection cells thus prompting greater and asynchronous NE release and more robust noradrenergic modulatory actions in decision-making circuits relative to movement generating circuits. This may facilitate decision making prior to movement generation. Perturbations in the functional anatomy and physiology described here may be related to neuropsychiatric conditions associated with dysregulation of the LC-noradrenergic system such as attention deficit hyperactivity disorder. Furthermore, these findings challenge the classical view of LC as a relatively homogenous modulator of forebrain activity and provide the basis for a renewed scientific interest in this region of the brain.
Adopción de tecnologías verdes y su influencia en las prácticas de responsabilidad ambiental. Percepciones de los trabajadores de hoteles
Authors: Martínez-Rubio Karen , Delgado-Cruz Alejandro , Vargas-Martínez Elva Esther
Published: October 2021

El objetivo de este trabajo fue analizar desde la percepción de los trabajadores la influencia de la adopción de las tecnologías verdes en las prácticas de responsabilidad ambiental. Para ello, se aplicó una encuesta a 385 trabajadores de 74 hoteles de la Ciudad de México. En el tratamiento de datos se empleó la modelación de ecuaciones estructurales por mínimos cuadrados parciales. Los resultados evidencian que las prácticas de responsabilidad ambiental están soportadas por la adopción de tecnologías verdes según la estructura de costos, el ahorro de recursos y los beneficios que ofrecen. El valor del trabajo radica en exponer la perspectiva de los trabajadores como stakeholders internos de las empresas.
Güven, Saygınlık ve Karizma: Toplumsal İtibarın Kadim Dayanakları
Authors: KOÇAK Abdullah , AYDIN İlhami
Published: October 2021

Sosyal bilimler alanında yapılan çalışmalarda, itibar kavramına genel olarak markaların ya da kamusal yapıların imajını test etme maksadıyla başvurulmaktadır. Çalışmalar genelde, ekonomik döngü içinde artı değer yaratmanın önemli ve zorunlu bir bileşeni olarak markanın toplumsal imajına odaklanmaktadır. ‘Toplum, sermaye yapılarına nasıl ve neden itibar atfeder?’ ya da ‘mevcut kurum/şirket itibarı nasıl zedelenir?’ gibi artı değeri daha da mümkün hale getiren sorular ekseninde itibar çalışmaları yapılmaktadır. Ancak toplumsal etkileşimin önemli bir referans kodu olarak itibar, kadimden bu yana toplumsal aktörün prestijini tanımlamak için de kullanılır. Sosyal, kültürel, ekonomik, sembolik ve başka sermaye bileşenleri ekseninde inşa edilen itibar, kişiye toplumsal etkileşim mekanizması içinde ayrıcalıklı bir otorite kazandırır. İtibardan yansıyan otorite yapılarının toplumsal alandaki meşruiyeti sosyolojik olarak ifade edilmiştir. Çalışma, itibarın toplumsal alandaki boyutuna odaklanmıştır. Saha araştırmasından kotalı örneklemle elde edilen bulgular bağlamında anlam kazanan bu araştırma, itibarın genel görünümlerini betimlemiştir. İtibar kaynakları resmedilirken, temel değişkenlerle itibar arasında anlamlı bir ilişkinin varlığı araştırılmıştır. Kuşak, cinsiyet, eğitim durumu değişkenleri, itibarı hangi kaynaklar bağlamında tanımladıkları irdelenmiştir. Ayrıca itibar tipolojileri sahip oldukları sermaye bileşenlerine göre gruplandırılmaları mümkün ise bu gruplandırmanın hangi kabuller üzerinden yapılabileceği de ifade edilmiştir. Elde edilen verilerden yola çıkarak itibara dair sonraki araştırmaların kapsamının ne olabileceğine dair tespitlere de yer verilmiştir.
Dijital İçerik Üretiminde “Haber Oyunları”; Gazetecilik Öğrencileri Üzerine Bir Araştırma
Authors: ELDEM ANAR Ülkü İlgi
Published: October 2021

Gazetecilik mesleği teknolojik gelişmeler ışığında sürekli bir değişim içinde yenilenmektedir. Yeni kavramlar geleneksel haber biçiminde de bir etkileşim süreci yaratmıştır. Çalışmanın konusu olan Haber oyunları da bu anlamda gerçek haber metinlerinin birer hikaye anlatısına dönüşerek simülasyon oyunu haline dönüşmesi ile meydana gelmektedir. Bu yeni kavramın hem literatür hem de araştırma anlamında çalışmalara konu olması alanın genişleyebilmesi ve gelişebilmesi için çok önemlidir. Bu araştırmada İletişim Fakültesi öğrencilerinin dijital içerik üretimi anlamında önemli bir kavram olan oyun ile haberin birleşiminden oluşan haber-oyunlarına olan farkındalıklarının ve bakış açılarının ölçülmesi amaçlanmıştır. Bu amaçla ilk olarak haber oyun kavramı araştırılarak tarihsel anlamda nasıl bir süreç geçirdiği yapılan literatür taraması ile ortaya konmaya çalışılmıştır. Çalışmanın araştırma kısmında etik onay izni alınarak toplamda 80 (seksen) öğrenciye Survey Monkey programı ile anket gönderilmiştir. Araştırmada örneklem olarak sınırlı sayıda öğrenciye ulaşılabildiğinden dolayı konu hakkında genel bir değerlendirme yapmaktan çok, ilerideki araştırmalara kaynak olabilecek bir çalışma yapılmıştır. Soru formları haber oyunu ile çeşitli değişkenlerin karşılaştırılarak yorumlanması üzerine oluşturulmuştur. Sonuçlar ise SPSS istatistik programı, Survey Monkey ve Excel programları kullanılarak değerlendirilmiştir. Araştırma sonucunda İletişim Fakültesi öğrencilerinin haber-oyunlarına karşı bilgi düzeylerinin ağırlıklı olarak başlangıç seviyesinde olduğu ortaya çıkmaktadır. Katılımcıların Haber Oyunlarına karşı bilgi düzeylerinin düşük olduğu, daha önce Haber Oyun deneyimlerinin az ya da hiç olmadığı, Haber Oyunlarının, toplumsal sorunların fark edilmesi için etkin bir yöntem olduğunu düşündükleri, fırsatları olursa bu tür bir dijital içerik üretimini uygulamak istedikleri ama bu tür bir içeriği oluşturabilecek yetiye sahip olmadıkları ortaya çıkmıştır.
Trajectory control of a two-position system consisting of a strike fighter and a cover fighter, providing an effective solution to the tasks of each of them
Authors: Zakomoldin D.V. , Bogdanov A.V. , Bulov V.A.
Published: October 2021

The problem of joint guidance of a strike fighter with an on-board radar station operating on radiation, and a cover fighter with an active jamming station operating on radiation, in the interests of improving the effectiveness of group actions of fighters, is due, in conditions of limited radio frequency spectrum, to the occurrence of unintentional interference at the input of the receiver of the onboard radar of the strike fighter, created by the active jamming station of the cover fighter. The purpose of this article is to synthesize the method of trajectory control of a two-position system consisting of a strike fighter and a cover fighter, which ensures the effective operation of the active jamming station of the cover fighter, while maintaining the information support capabilities of the strike fighter in the interests of its accurate guidance in the area of a possible missile launch, by introducing an energy quality indicator into the control signal. The result of the article is: the method of trajectory control of a two-position system as part of a strike fighter and a cover fighter, the results of modeling that allow us to evaluate the effectiveness of the developed method. The practical significance of the materials of the article lies in the fact that the implementation of the developed method of trajectory control of a two-position system as part of a strike fighter and a cover fighter will allow, by taking into account the energy quality indicator in the control signal of the cover fighter, in the form of a realizable suppression coefficient at the input of the on-board radar receiver, to ensure its flight path, ensuring maximum effectiveness of the cover of the strike fighter, while maintaining the ability of the on-board radar of the strike fighter to provide information for the algorithm of its guidance in the zone of possible launch of airto-air missiles.
ELECTRONIC PROPERTIES OF SINGLE-LAYER GERMANENE SURFACES WITH GAS ADSORPTION
Authors: Tran Phan Thuy Linh
Published: October 2021

The calculations of two - dimensional material structure of germanene and the adsorption of gas molecules (such as CO, CO2, N2) on germanene are performed by using density functional theory. The results show that germanene has zero-band gap energy and non-spin polarized characteristics. The adsorption of gas molecules on the surface of germanene plays a role in the tunable band gap. The adsorption energy of CO is lower than that of CO2 and N2, indicating that CO is more easily to be absorbed by the other two gases. This result makes germanene a potential candidate for CO adsorption devices, contributing to the reduction of the amount of CO in the air to create a clean beautiful environment.
The current status quo of self-learning and factors affecting self-study activities of students in School of Social Sciences and Humanities, Can Tho University
Authors: Nguyen Van Tron , Nguyen Le Man , Le Nguyen Phuong Anh , Chung Quan Tien
Published: October 2021

Self-study is a path of endogenous development to become perfect and develop personal abilities. Only when the self-learning force can be promoted, the learning results will be certain. Therefore, the issue of students’ self-study is mainly prominent in the current context. The study was conducted to find out the current situation of students' self-study as well as identify and analyze factors affecting self-study activities of students of the School of Social Sciences and Humanities in Can Tho University (CTU). Then, the study proposed several suitable measures aiming to support students who will have appropriate self-study methods to improve learning outcomes. Research data were directly collected by questionnaire method of 200 students at School of Social Sciences and Humanities, CTU. Descriptive statistical methods are mainly used in the study to analyze factors affecting self-study activities. The study has identified four groups of factors that affect students' self-study ability, that is, family, individual, school and teachers.
Role of allo-trilaminar dermal regenerative template in management of burns
Authors: Chittoria Ravi Kumar , Thomas Neljo , Mohan Padmalakshmi Bharathi , Koliyath Shijina , Pathan Imran , Kerakkada Nishad
Published: October 2021

Different methods of treatment options and dressing materials are available in today’s era of medical management of wounds. Trilaminar dermal regeneration template (TDRT) has been in use since the 1980s but owing to its high cost, its affordability and availability in third world developing countries is sparse. Here we have described our experience with the use of an indigenously made cost effective dermal regeneration template made from available materials in management of burns
Post covid-19 fungal infection and its impact on orthodontic practice: A review
Authors: Anas Mahammad , Konda Prasad , Hussain Arshad , Fareed Mohammed Baba , Kondody Rony T
Published: October 2021

As COVID-19 cases are reducing worldwide, the patients recovered from this disease are showing some complications include impact on lungs, kidneys, heart, and cases of a black fungal infection, called mucormycosis. There are a variety of bacterial and fungal co-infections which is associated with poorly controlled diabetes mellitus and other immune impaired condition. The COVID-19 exhibits, a specific pathophysiological feature, which will result in secondary fungal infections. The recent COVID-19 wave showed that many children and young people are testing positive for this disease. There is high chance for some of them can come across an orthodontic clinic. Oral mucormycosis is normally developed from the breathing of spores or through an open contaminated oral wound, affecting mainly immunocompromised patients. Oral mucormycosis is reported in some patient, following tooth extraction. The fungal spore can reach the body when there is a loss of anatomical continuity as can occur after a tooth extraction or in an ulcer. Chance for Post COVID-19 Mucormycosis in orthodontic patients are very rare. However, Orthodontist should take care when doing minor surgical procedure in the patient recovered from severe COVID-19 infection. Orthodontic appliances can increase the number of bacteria and fungus by limiting oral hygiene. Orthodontist should advise patients to the importance of maintaining basic oral hygiene measures, which include simple things like changing the toothbrush once they test negative, oral rinsing and brushing.
A novel method using 3D CBCT to assess anterior malar prominence among native Bangalore population- A descriptive study
Authors: Aamani Sanda , Hemanth M  , Sharmada B K  , Kabbur Karthik J , Kalladka Goutham
Published: October 2021

There is a lack of accurate three-dimensional studies to locate malar prominence for specified population, this study aims to locate the malar prominence using stable landmarks using CBCT.

To derive a novel method to accurately locate the malar prominence and to assess and compare the malar prominence between males and females among Bangalore population using 3D CBCT study.

All CBCT scans of study subjects belong to Bangalore population were collected from the pre-existing data available in Radiology imaging Solutions (CBCT centre), Bangalore during the period of September 10th to October 10th 2020. This is a descriptive study.

A total of 42 subjects including 21 Males and 21 females were assessed using full skull CBCT scans which were converted to DICOM format and reconstructed into 3D images using NEMOCEPH 3D software. Landmarks used to locate the malar prominence were Fzs, Z, Zm and Ans. The intersection of these landmarks is considered to be as constructed maxillozygion(My). For the accuracy of the constructed Maxillozygion point (My), the distance between the actual Maxillozygion (Mzy) and constructed Maxillozygion (My) is measured and calculated between left and right halves of males and females. Three Orthogonal planes constructed were Midsagittal, Axial and Coronal Planes and the linear measurements with reference to all three reference planes in both the groups are measured.

Student paired t- Test, Independent Student t Test, Mann Whitney Test.

The mean distance from Mzy and my between right and left half of the face was compared using student paired t- Test. There is no significant difference (p=0.35).

The mean values of the constructed anatomical landmark (maxillozygion) coordinated to three orthogonal planes between right and left sides of the face is compared using student paired T test and for both the genders (males and females) was compared using Independent Student t Test, and it is significantly higher in males as compared to females and it is statistically significant at (p=0.01).

The location of malar prominence using CBCT by a novel method for Bangalore population is found which can be helpful in diagnosis and treatment planning for malar augmentation, camouflage treatment in subjects with midface deficiencies.
RME as an aid to relieve excess crowding: Illustration with a case report
Authors: Alam Fatima , Bajjad Adeel Ahmed , Chauhan Arun Kumar
Published: October 2021

This case report describes the orthodontic treatment of a 13-year-old female patient who was diagnosed as Angle’s Class I malocclusion, posterior crossbite along with severe space deficiency. The space deficiency of 10 mm was noted in maxillary arch with complete block out of left central incisor, and posterior crossbite. The treatment plan presented non-extraction with rapid maxillary expansion. A bonded hyrax expander was used in a rhythm of 2 turns/day for 3 weeks, stabilized for 3 weeks, later followed by fixed appliance therapy on a 0.022 x 0.028 inch PEA on MBT prescription. The case was treated as non extraction. The treatment resulted in aesthetically pleasing facial profile with a normal overjet and overbite, and functional occlusion.
A review on: Medicinal properties of ginkgo biloba
Authors: Shaikh Shoheb S , Dighe Nachiket S
Published: October 2021

Traditional medicine and medicinal plants, as well as their study of modern chemical principles, may lead to the development of newer, less expensive medications. Ginkgo Biloba is well-known for curing a variety of ailments and is utilized in a variety of traditional medicinal formulations. Scientists and researchers from all over the world have spent decades studying the chemical composition of the entire Ginkgo Biloba plant, as well as its biological and pharmacological functions. These investigations established Ginkgo Biloba's medicinal potential in modern medicine and as a prospective drug discovery candidate. The current paper provides an overview of Ginkgo Bilobaethnobotany, phytochemistry, pharmacology, and toxicity.
Analytical tools in protein structure determination
Authors: Gupta Krishna R , Patle Uttam , Kabra Uma , Mishra P. , Umekar Milind J
Published: October 2021

Three-dimensional protein structure prediction from amino acid sequence has been a thought-provoking task for decades, but it of pivotal importance as it provides a better understanding of its function. In recent years, the methods for prediction of protein structures have advanced considerably. Computational techniques and increase in protein sequence and structure databases have influence the laborious protein structure determination process. Still there is no single method which can predict all the protein structures. In this review, we describe the four stages of protein structure determination. We have also explored the currenttechniques used to uncover the protein structure and highpoint best suitable method for a given protein.
Simultaneous analysis of eprosartan and hydrochlorothiazide in tablet formulation by High- Performance thin layer chromatography with ultraviolet absorption densitometry
Authors: Tambe Vrushali , Vichare Vijaya , Wagh Anupa , Wavhal Surekha
Published: October 2021

A new, simple, accurate, and precise high-performance thin-layer chromatographic method has been established for simultaneous analysis of Eprosartan and Hydrochlorothiazide from a tablet formulation. Standard and sample solutions of Eprosartan and Hydrochlorothiazide were applied to precoated 250 μm layer of silica gel G 60 F and the plates were developed with Chloroform: Acetonitrile: Glacial Acetic Acid (7:3:1,v/v/v) as mobile phase. Detection and evaluation of densitograms was performed densitometrically at 254 nm. The linear range was 200-700 ng/band with the retention factors of Eprosartan and Hydrochlorothiazide were 0.26± 0.02 and 0.44±0.02, respectively. The method was validated and successfully used for analysis of the drugs in tablets.
AESTHETIC INSTRUMENTATION FOR FORMING IMAGINED COMMUNITIES: THE PHENOMENON OF THE NATIONAL ANTHEM
Authors: Khoroshylov O.Y.
Published: October 2021

The article is devoted to the study of the experience of using aesthetic tools in the formation of national groups. The object of the research is the state anthems, as a concentrated manifestation of the self-interpretation of the political community. The methodology of this article is based on constructivism, which interprets nations as imaginary communities and focuses the attention of the researcher on the practice of using soft technologies of collective integration.

It`s addressed to the problem of using literary texts in the processes of collective integration made it possible to include not only representatives of political, but also creative elites in the list of subjects of social engineering.

It has been proved that the political significance of the national anthem is manifested through "texts` violence". It`s the ability of the ruling circles to transmit group values to the subordinate array, which is achieved due to the legislative consolidation of a generally binding status for a certain text and due to the aesthetic impact on the consciousness of members of the community.

The research methodology is presented by the using the procedures of the comparative method. It was carried out in such clusters as: justification of the right to exist (source of legitimation), "We are the image" of the commonality, common heroes, imaginary geography. It was achieved the identification of statistical patterns and features of the studied text arrays with analytical procedures for critical content analysis of the national anthems of European states. The results of the study confirmed the effectiveness of the procedures and tools of social engineering as one of the scenarios for the creation of national collectives in the European cultural area, substantiated the expediency of using the approved methodology to identify the cultural means of the nation-building process within the borders of Europe, and revealed the prospects of its application in relation to countries of the non-European cultural area.
INHIBITORS AGAINST INNOVATORS: THE EFFECT OF DELAYED TRANSIT TRANSFORMATIONS
Authors: Nazarenko S. I.
Published: October 2021

The article is devoted to the consideration of the complex issue of the reasons for the «delay» of political transit in the post-Soviet countries in general and in Ukraine in particular. The main author's hypothesis is the assumption that it is the activities of differently motivated subjects (inhibitors and innovators) in combination with the fundamental features of the cultural background of a particular country that determine the pace, overall trajectory and intermediate results of the democratization process. Particular attention is paid to the discussion around the question of whether transit is the only evolutionary trajectory or can be interpreted as a number of alternative directions of progress towards the standards of democratic governance.

The object of this article is the features of the socio-political transformation of the post-Soviet countries.

In turn, the subject of the article arises a ratio of the socio-political activity of innovators and inhibitors that is unique in national conditions, which directly affects the content and results of the democratic transition.

The complex nature of the central research problem presupposes the use of an appropriate methodology, the central place in which is occupied by: a systemic approach, comparative and structural-functional methods, institutional analysis. From the author's point of view, it is this arsenal of methods and research procedures that helps to clarify the nature of the negative results of the socio-political transformation of the transit process in such post-Soviet countries as Ukraine.

An analysis of the characteristic features of socio-political transformation in Ukraine indicates that the elite is motivated to conserve political informal practices and postpone changes in any way, and imitation reforms act as a legitimizer of the elite in the eyes of Western investors, creating a positive reputation for progressive reformers for its representatives.

The migration of reformers from the state of innovators to the state of inhibitors is due to their desire to become an elite in order to extract economic rent with the help of power. The idea is substantiated that the way out of the vicious circle of quasi-substitution of the elite is associated with the painstaking work of the real supporters of reforms to diagnose the vulnerable elements of the national trajectory of democratization and education of new generations - carriers of innovative types of thinking and supporters of values ​​and procedures of democracy.