bluuebunny/crossref_metadata_2025 huggingface dataset:
Sick Role Condition: Correlation of Knowledge Level on Covid-19 Transmission and Increasing Healthy Living Behaviours Practice in the Family
Authors: Kabelen Marista Christina Shally , Jahja Rusfadia Saktiyanti
Published: September 2022

This study reviews aspect of the Covid-19 pandemic that is currently engulfing Indonesia and the application of a clean and healthy lifestyle which is believed to be able to suppress the spread of the Covid-19 virus. This study aims to determine the level of public knowledge regarding the spread of Covid-19, the level of change in the application of the Healthy Living Behaviors, whether there is a correlation between the two variables, and how the relationship with Talcott Parsons' sick role theory on existing relationships and changes.  There have been several studies related to the relationship between the level of knowledge related to covid and behavior but very limited study that also analyzed the efforts to maintain the changes that have been made The research uses a quantitative method approach to test the existing hypotheses. The determination of the data sample was carried out by purposive sampling with the data population of Indonesian citizens resided in Jakarta-Bogor-Depok-Tangerang-Bekasi city (Jabodetabek), with an education level of one family member at least S-1. The results of the study concluded that there was a significant positive relationship with the coefficient value in a sufficient range of relationships between the variables. The level of public knowledge about the spread of Covid-19 is at a fairly high level, (4.03 out of 5). The level of change in the implementation of PHBS is low-medium (2.28 out of 5). The community is depicted as consciously choosing to keep their distance and withdraw from social interaction as an effort to prevent Covid-19, meaning they choose to be in a sick role condition even though they are physically fine.
Is There a Political Dynasty in The Head Village Election with Family Ties Candidates?: A Case Study in Pliken Village Banyumas
Authors: Widyastuti Tri Rini , Wardiyono F.X , Sutoyo Ignatius Suksmadi
Published: September 2022

This paper is about the rise of political dynasties in Indonesia. This phenomenon has become increasingly public attention since the nomination of President Joko Widodo’s son and son-in-law in the regional election in Solo and Medan. The village that has been considered far from the hustle and bustle of national politics also shows a similar phenomenon, namely the emergence of candidates for village head (kepala desa/kades) who are still related to family (pilkades sedarah).[1] But is pilkades sedarah a reflection of the existence of the political dynasty? This paper examines the village head election in Pliken Village, Banyumas Regency, which presents a married couple as village head candidates, using a qualitative approach. Collecting data through in-depth interviews, FGDs, observation, and documentation. The result of the study shows that the emergence of pilkades sedarah is not due to the existence of a political dynasty, but rather as pragmatic and rational reasons. Proposing a wife as a “competitor” is a pragmatic attitude just to get around the rules that prohibit a single candidate in village head election. The absence of other candidates who dared to oppose the incumbent was due to the rationality of the people who saw the high cost of candidacy which was not proportional to the official income of the village head. They also assessed that the prestige of the incumbent village head was high, both in terms of educational qualifications and achievements, so that the opponent’s chances of winning the competition were small.Keywords: political dynasty, village head election, blood relation[1] Pilkades sedarah is a term to describe that village head candidates still have family or blood relations.
Impact of gender-affirming treatment on bone health in transgender and gender diverse youth
Authors: Ciancia Silvia , Dubois Vanessa , Cools Martine
Published: September 2022

Both in the United States and Europe, the number of minors who present at transgender healthcare services before the onset of puberty is rapidly expanding. Many of those who will have persistent gender dysphoria at the onset of puberty will pursue long-term puberty suppression before reaching the appropriate age to start using gender-affirming hormones. Exposure to pubertal sex steroids is thus significantly deferred in these individuals. Puberty is a critical period for bone development: increasing concentrations of estrogens and androgens (directly or after aromatization to estrogens) promote progressive bone growth and mineralization and induce sexually dimorphic skeletal changes. As a consequence, safety concerns regarding bone development and increased future fracture risk in transgender youth have been raised. We here review published data on bone development in transgender adolescents, focusing in particular on differences in age and pubertal stage at the start of puberty suppression, chosen strategy to block puberty progression, duration of puberty suppression, and the timing of re-evaluation after estradiol or testosterone administration. Results consistently indicate a negative impact of long-term puberty suppression on bone mineral density, especially at the lumbar spine, which is only partially restored after sex steroid administration. Trans girls are more vulnerable than trans boys for compromised bone health. Behavioral health measures that can promote bone mineralization, such as weight-bearing exercise and calcium and vitamin D supplementation, are strongly recommended in transgender youth, during the phase of puberty suppression and thereafter.
The Toxic Effects of Lead on Seedling Growth Development of Euphorbia Hirta Forsk (Weed) and Sporobolus Coromandelianus (Retz.) Kunth (True Grass)
Authors: Urooj Faiza , Iqbal Zafar , Shafiq Muhammad
Published: September 2022

Lead is considered a toxic heavy metal and released in the air, water and soils due to auto wheels, industrial and anthropogenic activities which influence on plant growth, fauna and environment. It is hypothesized that plants are capable of showing different responses of toxicity and tolerance to metals stresses. The objective of this study is to investigate the influence of one of the highly toxic heavy metal, lead (Pb) on the seedling growth of native plant species, Euphorbia hirta Forsk and Sporobolus coromandelianus (Retz.) Kunth in pots as there are very few data available in the literature on this toxicity subject. It is important to compare both genotype under various level of lead treatment. The seedlings of E. hirta and S. coromandelianus showed different effect when treated with 20, 40, 60, 80, 100 as compared without 0 ppm concentrations of lead. The results of the present studies showed the statistically significant (p<0.005)influences of lead 40 ppm treatment on number of leaves, leaf area and seedling dry weight of S. coromandelianus. Lead treatment at 60 ppm significantly reduced shoot, root and and total seedling height of S. coromandelianus. Lead treatment at 40 ppm also showed significant decreased on shoot, seedling length and number of leaves of E. hirta.

The seedlings of E. hirta and S. coromandelianus were also used for the development of tolerance indices percentage to different level of lead. The seedlings of E. hirta and S. coromandelianus showed changes in values of tolerance indices. Lead treatment at 20 ppm showed a positively decreasing influence on the tolerance indices of E. hirta and S. coromandelianus. Increase in lead level at 80 – 100 ppm highly decreased the tolerance indices percentage of E. hirta and S. coromandelianus as compared to control. The seedlings of S. coromandelianus showed tolerance (68.38%) as compared to E. hirta (50.79%) to lead at 100 ppm. The obtained data could be useful for a wide range of researchers working in this aspect.
Optimal sowing times and irrigation schedule of the chickpea (Cicer Arietinum L.) in semi-arid regions
Authors: Tarı Ali Fuat , Bahçeci Barış
Published: September 2022

The purpose of this study was to determine the effects of different sowing times and irrigation schedules on seed yield and water use of chickpea in Central Anatolia's semi-arid conditions. For two years, field trials were conducted using a split-block trial design with three replications. The study addressed two sowing times as well as five irrigation treatments. While the effect of sowing time on grain yield varied by year, the effect of irrigation on grain yield was significant for both sowing times. At both sowing times, the three irrigation treatments (flowering, pod set, and pod filling) produced the highest grain yield. The efficiency of water use was higher in late sowing than in early sowing. While plant water consumption increased during the early sowing period, the amount of irrigation water decreased. The seasonal yield response factor early sowing, on the other hand, was lower than in late sowing.
Defining and Predicting Consumers Bread Choices based on Socio-Demographic Characteristics and Healthy Living Orientations
Authors: Çobanoğlu Ferit , Kahraman Ayşe Demet , Öğüt Serdal
Published: September 2022

The bread still constitutes an essential part of meeting the daily nutritional requirement. The primary purpose of this study is to examine the socio-demographic characteristics of individuals and their bread consumption preferences and perceptions with a focus on quality and healthy life. The data are obtained digitally with 9583 consumers from survey questions created on google form throughout Turkey throughout the year 2020. First, descriptive statistics of the answers to the comprehensive survey questions are revealed. Then, correlation analysis is conducted to show the relationships between the variables, in line with each sub-objective set up under the primary purpose. Finally, by using some data mining and machine learning algorithms, it is tried to reveal future expectations based on some main determinant parameters such as health and quality expectation for bread consumption of consumers. All statistical and inferential evaluations are made using the Konstanz Information Miner (KNIME) analytics platform. The findings discover that increasing income and education level in bread consumption improves the level of awareness about health and quality of life in people, and these attitudes and perceptions bring about a proportional decrease in bread consumption of individuals. On the other hand, as a vicious circle, it reveals that the sedentary life brought by work-life in modern society causes an increase in body weight and an unhealthy living ecosystem. This study, it is tried to define and predict the behavioral attitudes of consumers toward bread consumption. The findings can offer meaningful advice to all actors and political decision-makers involved in the bread market and supply chain and consumers.
Assessment of Processing Quality Traits of Different Potato Genotypes in Konya
Authors: Çöl Keskin Nursel
Published: September 2022

This study aimed to determine the potato breeding lines that show superior processing quality traits and can be candidate variety by selection. The study was conducted according to The Randomized Plots Trial Design with four replications in 2019 and 2020 years. In the study, 26 potato breeding lines developed by Selcuk University, Faculty of Agriculture, Department of Field Crops, and 4 registered varieties as plant material were used in the two years. The varieties and lines were done harvest in the fields and then the genotypes were evaluated according to processing quality traits. In the study; dry matter ratio (%), chips yield (%), French fries yield (%), chips, and French fries color (L*, b*) parameters were examined. Dry matter ratio, chips yield and French fries yield, and chips and French fries color values were found important statistically in terms of years, genotypes, year x genotype interactions. Values of chips and French fries color were varied from only genotypes averages. According to two years average, results showed large variations for examined parameters; dry matter ratio changed between 16.8-20.9 %, chips yield was 34.1-51.0 %, French fries yield was 30.7-44.9 %, chips color values (L*, b*) were 19.4-67.1, 8-44 and French fries color values (L*, b*) were 11.4-71.5, 13.5-58.2, respectively.
Reactions of Some Grapevine Rootstock Cuttings to Mutagenic Applications
Authors: Kara Zeki , Doğan Osman
Published: September 2022

Grapevine (Vitis spp.) is one of the most important socio-economically important plants in the global scale, and the need for its breeding is increasing. In viticulture, mutation is more promising than crossbreeding in breeding new genotypes from natural genetic diversity. Polyploid plants outperform their diploid relatives in several respects. In this study, the efficacy of oryzalin and N2O mutagens in the induction of polyploidy was investigated by applying different doses and durations to the forced cuttings of 41B [Chasselas (Vitis vinifera L.) × Vitis berlandieri Planch)] and Fercal [(Vitis vinifera x Vitis berlandieri) × 333 EM] rootstocks. LD50 values of mutagen applications were determined, morphological and cytological effects were examined by macroscopic, microscopic, and cytological methods. Application time and dose increase of mutagens decreased LD50 values. As a result of mutagen applications, leaf thickness and chlorophyll content of the surviving plants increased. Applications increased stomatal sizes, decreased their density, increased chloroplast numbers, increased leaf thicknesses and partially SPAD values. It was determined that they were not polyploid in the confirmation test performed with flow cytometry (FC) analyses in 4 Fercal and 1 41B samples that were assumed to be mutant by stoma and chloroplast examinations. After that, it was thought that it would be appropriate to try vegetative material with actively dividing cells, such as nodal cuttings, in the studies of obtaining polyploid individuals on grapevine rootstocks
Effects of Plant Growth Promoting Rhizobacteria on Growth, Yield and Fruit Quality of Pomegranate (Punica granatum L.)
Authors: Acar Osman , Pırlak Lütfi , Dönmez Mesude Figen
Published: September 2022

This study was carried out in a commercial pomegranate garden in Denizli, in 2017-2018 in order to determine the effects of Pseudomonas sp. HV 5 and Micrococcus luteus GC- subgroup B MFDV3 bacterial strains, which are potentially capable of improving plant yield and development, on plant growth, yield and quality. The effects of bacterial application on shoot diameter, fruit width, fruit size, fruit juice content, pH, acidity and yield per tree were statistically in significant but the effects on fruit weight, fruit volume and fruit juice C vitamins were found to be significant. Concomitant use of HV5 and MFDV3 bacteria resulted in increased fruit weight, volume, and amount of vitamin C in fruit juice compared to control. According to the results of the research, it was concluded that the bacterial strains used had a positive effect on fruit juice and vitamin C only, so that different application forms and doses should be tested.
Examination of Milk Samples, obtained from the Different Cattle breeds in the First Lactation, by Means of Discriminant Analysis
Authors: İkten Cengiz , Keskin İsmail
Published: September 2022

By means of discriminant analysis, it can be identified which class the individuals (data) desired to be classified. In this study, it was aimed to identify that the milk samples belong to which breed, applying discriminant analysis to the milk samples taken from the cattle breeds (19 heads of Jersey, 53 heads of Holstein and 27 heads of Charolaise) in the first lactation. As a conclusion of the study, proper classification actualized in the rate, which can be considered quite high like 90.6%, according to the milk components (fat, protein, lactose, density, pH and conductivity) of Holstein Cattles. This rate actualized as 63.2% in Jersey and 25.9% in Charolaise. It was identified that the rate of general classification of non-linear analysis, used in discriminating Holstein, Jersey and Charolaise breeds from their milk components, was 67.7%.
Inhibitory Effect of Oregano and Laurel Essential Oils and Their Main Com-ponents on Seed Germination of Some Weed and Crop Species
Authors: Tursun Nihat , Işıkber Ali , Alma Mehmet Hakkı , Usanmaz Bozhüyük Ayşe
Published: September 2022

The essential oils from oregano (Origanum syriacum L.) and laurel (Laurus nobilis L.), and their main components, namely, carvacrol, 1,8-cineole and α-pinene, were tested to determine their inhibitory effects on the seed germinations of three different weeds [redroot amaranth (Amaranthus retroflexus L.), wild licorice (Glycyrrhiza glabra L.), curled dock (Rumex crispus L.) and cutleaf ground-cherry (Physalis angulata L.)] and three crops [(wheat (Triticum aestivum L.), corn (Zea mays L.) and cotton (Gossypium hirsitum L.)]. Gas chromatography/mass spectroscopy (GC-MS) analysis showed that 1,8-cineole and carvacrol were the major components of laurel and oregano essential oils, respectively. An in-vitro bioassay seed germination test showed that oregano essential oil and carvacrol completely inhibited the germination of weeds at all the concentrations ranging from 1 to 5 µl/Petri dish, while seed germination of test weeds significantly decreased with increasing of the concentrations of laurel essential oil and its main components, 1,8-cineol and α-pinene ranging from 5 to 20 µl/Petri dish. Oregano essential oil and carvacrol were totally ineffective on cotton and corn germination (except for the concentration of 5 µl/Petri dish of cavracrol), whereas they had a strong inhibitory activity against wheat seeds. On the other hand, the laurel essential oil and its main component, 1,8-cineole, showed less selective action on test crop species. It could be concluded that volatile oil from O. syriacum and its main component, cavracrol, possessed a strong inhibitory effect on germination of the weeds and was totally selective action on some crops, and could be utilized as bioherbicide for future weed management programmes.
Las protestas feministas en México durante el año 2020. Causas y consecuencias
Authors: Abarca Reyes Juan Fernando
Published: September 2022

A lo largo de las últimas décadas, el movimiento feminista se ha encargado de defender los derechos de las mujeres en la sociedad mexicana, pero su lucha aún está lejos de terminar. Una muestra de ello son las protestas que se llevaron a cabo a lo largo de todo México por mujeres representantes de dicho movimiento en pleno 2020, incluso a pesar de seguir declarada la pandemia por covid-19 que tanto ha afectado y paralizado las actividades en todo el mundo. La presente investigación tuvo como objetivo analizar las principales causas y consecuencias de las protestas y movilizaciones de los grupos feministas durante el año 2020 en México, para lo cual se diseñó un estudio de tipo cualitativo, utilizando como principal técnica de recolección de datos la investigación documental. Se analizó a detalle las dos principales causas de dichas manifestaciones y sus respectivas consecuencias, a saber: presionar al Estado para que actúe en contra de los constantes crímenes de violencia ejercidos contra las mujeres, y que les sea otorgada a las mujeres la maternidad libre a través de la legalización del aborto.
Las Casas de Juventud: un escenario para la construcción de paz territorial
Authors: Jaime Ruiz Edwin Diomedes , González Alvarado Jennifer Katerinne , Pascagasa Usaquén María Alejandra
Published: September 2022

Los jóvenes han sido protagonistas en la construcción de paz durante los últimos años, luego de estar asociados a imaginarios de delincuencia, estigmatización y exclusión. El presente estudio se sitúa en la ciudad de Bogotá y pretende demostrar la importancia que tienen las acciones colectivas de los jóvenes en la construcción de paz en los territorios urbanos, lo que da lugar a nuevas ciudadanías y formas particulares de entender las juventudes desde la institucionalidad y las iniciativas juveniles. Estos actores despliegan acciones públicas en cada localidad, donde la presencia institucional está representada en la implementación de las políticas públicas. Para el análisis propuesto, se retoman las prácticas específicas de organizaciones juveniles lideradas por actores que dinamizan la construcción de paz en varias localidades de Bogotá a través de las Casas de Juventud. Estos lugares son puntos de encuentro, diálogo y diversidad entre las comunidades de base y la institucionalidad, donde se aborda la percepción de la paz y su construcción en sus propios territorios, en concordancia con sus necesidades y prioridades como comunidad. Para el desarrollo de esta propuesta se aplicaron varias herramientas metodológicas, como la revisión documental, la etnografía digital, las entrevistas semiestructuradas y los grupos focales en tanto posibilidades para comprender los mundos juveniles.
Movimiento estudiantil feminista chileno: impactos en los movimientos sociales y la sociedad civil
Authors: Rojas Vilches Natalie Sofía
Published: September 2022

Los movimientos sociales en el mundo han sido catalizadores de una serie de luchas que han fortalecido los sistemas democráticos de donde han irrumpido. Este artículo desarrolla el caso del movimiento estudiantil feminista chileno, el cual, aunque se constituyó como un petitorio universitario por el fin al abuso y al acoso sexual en los planteles de educación, fue capaz de traspasar la esfera cultural chilena y desde ahí atravesar un proceso de feministización de los movimientos sociales y de la política chilena. A través de la aplicación de metodologías feministas y de conocimiento situado, se llega a la conclusión de que estamos frente a un giro hacia el feminismo en la sociedad chilena, pues este se posiciona ya no como un extra de los movimientos sociales o los partidos políticos, sino como parte constituyente de los mismos.
Human ascariasis, an evolutionary complex relationship between host and parasite
Authors: Baldi Mario , Baldi Norberto
Published: September 2022

La ascariasis es una enfermedad parasitaria que diezma la salud de cientos de miles de seres humanos, especialmente en los países en desarrollo. Sin embargo, la falta de profilaxis adecuada del parásito, asociado con un mayor riesgo de sufrir enfermedades inmunes, es un problema principalmente en los países desarrollados donde la prevalencia del parásito es muy baja. La relación evolutiva y los mecanismos por los cuales el parásito fue capaz de colonizar y establecerse en el huésped humano aún no se han descifrado. Del mismo modo, los mecanismos inmunes (proximales) de respuesta del huésped para eliminar o controlar el parásito no se entienden completamente. La comprensión de estos mecanismos nos permitirá establecer mejores tratamientos médicos, evitando efectos indeseables y más enfocados en el control de la parasitosis, así como para la terapia de estas enfermedades inmunológicas asociadas con la relación huésped-ascárido.
The Effect of Coaching Leadership Styles Towards Motivational Factors Among Selangor and UITM Lions Rugby Players
Authors: Mohd Fisal Muhamad , Kamal Azlan Ahmad
Published: September 2022

The objective of this research is to investigate the effect of coaching leadership styles towards motivational factors among Selangor and UITM Lions rugby players. The sample was chosen from two of the best rugby team in Selangor respectively. Purposive sampling was employed to pick the sample of 66 rugby players. As the primary instrument for acquiring information about coaching leadership styles and motivational factors, they were given an online questionnaire to complete. The Leadership Scale for Sport - 15 Version (LSS-15) questionnaire is used to determine coaching leadership styles, while the Sport Motivation Scale-II (SMS-II) is used to determine motivational factors. All data in this study was analysed using the Statistical Package for Social Science (SPSS) version 26.0. The mean of the data was generated using descriptive analysis to determine the preferred coaching leadership styles among rugby players and the motivational factors among rugby players. The relationship between coaching leadership styles and motivational factors among rugby players was analysed using Spearman Correlation. The researcher discovered that there is significant relationship between leadership styles towards motivational factors.
Use of Albumin in the NICU: An Evidence-based Review
Authors: Rustogi Deepika , Yusuf Kamran
Published: September 2022

Albumin is the most abundant protein in human blood with distinctive functions throughout the human body. Low albumin levels are a predictor of mortality as well as disease outcome in children and adults. However, the clinical significance of hypoalbuminemia and the role of albumin infusions in NICUs remain unclear and controversial.
Lesion-Specific Congenital Heart Disease Mortality Trends in Children: 1999 to 2017
Authors: Lynn Melodie M. , Salemi Jason L. , Kostelyna Stefan P. , Morris Shaine A. , Tejtel S. Kristen Sexson , Lopez Keila N.
Published: September 2022

OBJECTIVE

Congenital heart disease (CHD) is a leading cause of premature death in infants and children. Currently limited data are available regarding lesion specific mortality over time. Our study aimed to describe pediatric mortality trends by CHD lesion in the United States.

METHODS

We conducted a 19 year analysis (1999 to 2017) of publicly available, deidentified multiple cause of death data compiled and produced by the National Center for Health Statistics. Analysis was stratified by CHD diagnosis and age using 3 age categories (infants, 1 to 4 years, and 5 to 17 years). Temporal trends of CHD mortality and the effect of contributing risk factors were analyzed by using joinpoint regression.

RESULTS

Mortality was highest for in infants for all CHD lesions, in particular for total anomalous pulmonary venous return. Significant declines in infant CHD mortality occurred for most other lesions. Contributing risk factors, including prematurity, extracardiac birth defects, and genetic conditions, occurred in 19% of infant CHD deaths and demonstrated worse mortality trends in the majority of lesions. Mortality rates remained highest for single ventricle lesions in all ages, with an infant mortality rate plateau in the later half of the study and progressive increasing mortality rates for children 5 to 17 years.

CONCLUSIONS

CHD mortality is decreasing for most lesions. Because of the heterogenicity of CHD lesions, there is expected variability in mortality trends by lesion and age group. Single ventricle lesions continue to contribute most heavily to premature death because of CHD demonstrated by significant increases in mortality rate for children aged 5 to 17 years.
Цифровізація публічного управління вищою освітою в Україні на сучасному етапі державотворення
Authors: Шеломовська Оксана
Published: September 2022

Досліджено сучасний стану впровадження інформаційно-комунікаційних технологій в систему державного управління вищою освітою в Україні. Наголошено, що інформатизація державного управління сферою вищої освіти є однією зі складових частин побудови повноцінних е-демократії та е-урядування в нашій країні. На основі порівняння положень нормативно-правових актів і реальної ситуації з’ясовано стан функціонування  електронна система щодо збору та аналізу фінансових даних  за результатами діяльності у сфері вищої освіти і єдиної державної електронної бази з питань освіти. Визначено їх роль у державному управлінні галуззю, функції та переваги. Висвітлено повноваження окремих управлінських структур у внесенні даних до електронних систем управління вищою освітою.
Цифрові механізми доступу до адміністративних послуг: мобільна цифрова валіза
Authors: Піскоха Наталія
Published: September 2022

В умовах обмеженого доступу до Інтернету, для забезпечення онлайн доступу до адміністративних послуг в Україні використовуються мобільні робочі місця адміністратора ЦНАП. Такі робочі місця укомплектовані відповідними технічними засобами і отримали назву "мобільних цифрових валіз". Окрім того, завдяки таким валізам українці, які через те, що їм важко пересуватися і не можуть самостійно відвідувати Центри надання адміністративних послуг, отримують можливість доступу до цифрових послуг. Досліджено особливості використання мобільних цифрових валіз у пілотних містах, де за підтримки проекту EGAP та місцевої влади вже діють  віддалені робочі місця адміністраторів Центрів надання адміністративних послуг. Показано правове підґрунтя та технічні можливості використання цифрових технологій для забезпечення взаємодії громадян з органами влади.
Позиція Канади щодо нової ролі Сполученого Королівства в Європі
Authors: Кибіч Яна
Published: September 2022

Дана стаття висвітлює особливості відносин Канади з Європейським Співтовариством та Великою Британією в розрізі Brexit. Розглянуто основні виклики та невизначеності в політичній, економічній та соціальних сферах, з якими стикнулася Канада після того як Британія вирішила залишити ЄС. Очевидно, що найвагомішою проблемою для Канади наразі стало питання торгово-економічного характеру, оскільки Brexit припиняє дію Всеосяжної економічної й торговельної угоди (CETA) між ЄС і Канадою. Канадському уряду доведеться домовитися про нову двосторонню угоду зі Сполученим Королівством, адже левова частка канадської торгівлі товарами в рамках договору відбувається з Великобританією.

Постановка наукової проблеми та її значення. За останні п’ять десятиліть відносини Канади та Європи базувалися на двох основних стовпах: колективної безпеки через членство в Організації Північноатлантичного договору (НАТО) та економічного співробітництва шляхом двосторонніх угод з Європейським Співтовариством, а пізніше Європейським Союзом (ЄС). У контексті кожного з цих напрямків принциповим для Канада було співробітництво з Сполученим Королівством. Сьогодні для Канади Великобританія залишається найбільш довіреним партнером у Європі – її головним союзником у сфері безпеки, так званим посередником у політичній співпраці з ЄС, та головною точкою доступу до Єдиного ринку. Brexit зумовить кінець цієї усталеної моделі взаємодії; це створить потребу Канаді знову окремо налагоджувати економічні, політичні та, можливо, навіть безпекові відносини з Великобританією та з ЄС.

Метою даної статті є дослідження урядової позиції та громадської думки канадського суспільства стосовно виходу Великої Британії з ЄС та ймовірних наслідків цього процесу для Канади.

Основні одержані висновки. Проаналізувавши опрацьовані статистичні дані опитувань громадян Канади після 2016 року, яке було проведено командою вчених впливового канадського аналітичного центру Nanos Research, виявлено негативний вплив Brexit на позиціонування канадцями Великобританії в ролі міжнародного партнера. Визначено, що, канадці надають пріоритет відносинам з Європейським Союзом на противагу співпраці з Британією, яка вирішила залишити Співтовариство. Однак існують чіткі відмінності у сприйнятті між прихильниками різних політичних партій, а отже, Brexit має потенціал стати політично спірним питання в межах Канади.

Уважно дослідивши про- та анти-Brexit настрої канадської політичної верхівки, встановлено неформальну закономірність, згідно з якою ліберали традиційно багатосторонні, консерватори більше схиляються до Великобританії та Співдружності.
Nurturing Life Skill Education in an Environment-Based Pesantren
Authors: As'ad Mahrus , Hakim Lukman
Published: September 2022

The success of educational institutions can be seen from their ability to develop their studentsâ€™ life skills including self-potential, skills, and independence development. This study aims to investigate the implementation of environmental-based life skills education at PPBU (Pondok Pesantren Agroecologi Biharul Ulum) Cisarua, Bogor. This study uses a qualitative method. Data was collected by using observation, interview, documentation, and triangulation techniques. Data analysis includes data reduction, data presentation, and drawing conclusions. The results showed that life skills education at PPBU was implemented by using an integrative curriculum based on the theological teachings of the Qur'an with the spirit of local wisdom values. The curriculum was implemented in a number of programs for studentsâ€™ development in terms of their personal, social, academic, and vocational skills.
Benefit of educational intervention on Autoinjector Technique for caregivers and paediatric patients with food allergies: A literature review
Authors: Trujillo Juan , Cronin Caoimhe
Published: September 2022

Background and objective: The incidence of food allergy among children is on the rise. Children who are diagnosed with a food allergy receive long-term treatment for allergy management from allergy specialists, nurses and dieticians. This management may include the prescription of an adrenaline autoinjector (AAI) if the child is at risk of a severe allergic reaction (anaphylaxis). Therefore, it is important that parents of children with allergies are trained in the recognition of anaphylaxis and in the correct administration of an AAI. However, many parents are unable to correctly administer an AAI when assessed. The aim of this study is to review the current literature on caregiver’s and paediatric patients’ ability to use an AAI.
Methodology: An electronic search to evaluate AAI technique in caregivers and children with food allergy was conducted. A total of 323 articles were screened in which 10 studies were reviewed.
Results: Seventy-eight percent of parents who had never been trained in the use of an AAI were unable to trigger it. In studies where paediatric patients’ ability to use an AAI was assessed, a mean score of 7.78/9 was derived for AAI knowledge among adolescents.
Conclusion: Caregivers and patient’s ability to use an AAI was inconclusive, and further research should address the validation of an assessment tool for AAI use. A significant improvement in AAI use was found after an educational intervention. This highlights the need for improved education for allergic individuals and their caregivers, and further study should explore what are the best educational methods to meet these needs.
Inhibition of KLF6 reduces the inflammation and apoptosis of type II alveolar epithelial cells in acute lung injury
Authors: Chen Qingbin , Jia Zhen , Qu Changjing
Published: September 2022

Background: The development of acute lung injury (ALI) into a severe stage leads to acute respiratory distress syndrome (ARDS). The morbidity and mortality of ALI and ARDS are very high. Objective: This study is aimed to explore the effect of Krüppel-like factor 6 (KLF6) on lipopolysaccharide (LPS)-induced type II alveolar epithelial cells in ALI by interacting with cysteine-rich angiogenic inducer 61 (CYR61).
Material and Methods: ALI mice model and LPS-induced type II alveolar epithelial cells were conducted to simulate ALI in vivo and in vitro. The messenger RNA (mRNA) and protein expression of KLF6 in lung tissues were detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and Western blot analysis. Pathological changes in lung tissues were observed by hematoxylin and eosin (H&E) staining. The viability and KLF6 expression of A549 cells treated with different concentrations of LPS were detected by cell counting kit-8 (CCK-8) assay, RT-qPCR, and Western blot analysis. After indicated treatment, the viability and apoptosis of A549 cells were analyzed by CCK-8 and TUNEL assays, and the inflammation factors of A549 cells were detected by Enzyme-linked-immunosorbent serologic assay, RT-qPCR, and Western blot analysis. The combination of KLF6 and CYR61 was determined by chromatin immunoprecipitation (ChIP)-PCR and dual-luciferase reporter assay.
Results: KLF6 expression was increased in lung tissues of ALI mice and LPS-induced A549 cells. Interference with KLF6 improved the viability, reduced the inflammatory damage, and promoted the apoptosis of LPS-induced A549 cells. In addition, KLF6 could bind to CYR61. Interference with KLF6 could decrease CYR61 expression in LPS-induced A549 cells. LPS also enhanced the TLR4/MYD88 signaling pathway, which was reversed by KLF6 interference. The above phenomena in LPS-induced A549 cells transfected with Si-KLF6 could be reversed by overexpression of CYR61.
Conclusion: Inhibition of KLF6 promoted the viability and reduced the inflammation and apoptosis of LPS-induced A549 cells, which was reversed by CYR61.
DETERMINATION OF THE VALUE OF THE STABILITY MARGIN COEFFICIENT BASED ON THE ANALYSIS OF THE STRESSED STATE OF THE SOIL MASS IN THE FRAMEWORK OF THE LINEAR THEORY OF ELASTICITY
Authors: Bogomolova O. A , Zhidelev A. V
Published: September 2022

The introduction lists the main disadvantages of the traditionally used methods for calculating the stability of slopes and slopes and presents a calculation method in which, for the first time, in our opinion, an attempt was made to construct the most dangerous "slip line" based on the analysis of the stressed state of the soil massif. Further, in the first chapter of the article, three possible approaches to solving the problem of determining the angle of inclination of the most probable shear site at the studied point of the soil massif, based on the analysis of its stress state, are presented and analyzed. The second chapter presents the results of calculating the value of the coefficient of stability of the soil slope by L.G. Fisenko (one of the traditional calculation methods) for two types of sliding line: circular cylindrical (classical case) and constructed by the method of N.S. Nikitin taking into account the operating stresses; and by V.K. Tsvetkov - A.N. Bogomolov. All calculations are performed for one object, the geometric parameters of which and the numerical values of the physico-mechanical properties of the composing soil are given in the article cited below by S.N. Nikitin. As a result, it turned out that the first two coefficients of the margin of stability are respectively equal to K 1 = 1.6 and K 2 = 1.75, and the value of the third coefficient of the margin is equal to K 3 = 2.18. Comparing this value with the values of the coefficients of the margin of stability calculated by the method of S.N. Nikitin and the method of L.G. Fisenko, we see that it is 26 and 20 % higher, respectively, while K 2 > K 1 is 9.4 %. Based on the analysis of the calculation results for the example considered in this paper, it can be stated that methods based on the analysis of the stressed state of the soil mass give higher values of the stability margin coefficients than traditionally used. Thus, the value of the slope stability margin coefficient calculated by the method of V.K. Tsvetkov - A.N. Bogomolov turned out to be equal to K 3 = 2.18. Comparing this value with the values of the stability margin coefficients calculated by the method of S.N. Nikitin and the method of L.G. Fisenko, which are respectively equal to K 1 = 1.75 and K 2 = 1.6, we see that it is 20 and 26 % more than them, respectively. At the same time, K 1 > K 2 by 9.4 % - this indicates that taking into account the stresses during the construction of the sliding line makes its shape different from the circular cylindrical one, which affects the value of the stability margin coefficient.
THE USE OF METHANOGENIC PLANTS BASED ON SOLID COMMUNAL WASTE IN LOW-RISE CONSTRUCTION
Authors: Afonin K. V , Zilina T. S , Zagorskaya A. A , Pavlova M. N
Published: September 2022

The authors consider the main aspects of local utilization of waste of low-rise buildings by methane fermentation with the subsequent production of secondary energy resources. Currently, the generation of methane in artificial conditions is an intensively developing industry. Previously, the authors studied the experience of the regions of Russia in the disposal of solid domestic waste. It is revealed that the processing of solid municipal waste in bioreactors can be carried out with the joint fermentation of various wastes. This is also possible by adding existing accelerators for the methane fermentation reaction. The quantitative characteristics of waste generated on the territory of individual residential low-rise buildings have been studied. From the total volume to be disposed of, waste potentially suitable for the formation of the initial substrate was isolated. The main properties of raw materials for the necessary generation of bio methane have been determined. The specific methane yield during its constant generation has been calculated for various combinations of municipal waste of low-rise buildings. The paper presents a general concept of local processing of municipal solid waste and describes the scheme of the methane generating plant. The dimensions and technical characteristics of the installation for obtaining bio methane from waste at the place of their formation in residential buildings have been determined. In addition, the calculation of thermal energy produced on the base on generated methane was carried out. And it was found that the introduction of methane-generating plants in the technical systems of low-rise buildings allows to increase their energy efficiency, reduce the load on existing landfills of solid domestic waste and achieve maximum utilization of waste from residential areas.
THE USE OF METALLURGICAL CALCIUM, ALUMINUM AND IRON-CONTAINING SLAGS IN THE PRODUCTION OF HEAT-RESISTANT CONCRETE BASED ON ORTHOPHOSPHORIC ACID
Authors: Abdrakhimov V. Z
Published: September 2022

The objects of research are: ferropyl from self-disintegrating slags of low-carbon ferrochrome, slag from smelting without carbon ferrochrome, ferrite-calcium slag and heat-resistant concrete. Due to the fact that the Russian budget does not provide funding for geological exploration and other survey work to determine the quantity and quality of raw materials for the production of construction products, it is necessary to conduct research on the use of technogenic raw materials as raw materials. The use of technogenic raw materials in the production of construction materials practically reduces many costs not only for geological exploration, but also for the arrangement, including the operation of quarries, to zero. Metallurgical industries (non-ferrous and ferrous) in Russia emit a third of all available emissions from industrial enterprises into the atmosphere, while the volume of metallurgy products (non-ferrous and ferrous) is only 17 % of the total domestic industry. In this work, metallurgical waste was used for the production of heat-resistant concrete: as a calcium-containing component, ferropyl from self-disintegrating slags of low-carbon ferrochrome, as an iron-containing component, ferrite-calcium slag, waste from the processing of copper-zinc concentrates, which is a light yellow material slowly cooled to complete scattering, resembling fine sand, and as an aluminum-containing slag from smelting without carbon ferrochrome. Studies have shown that ferrite-calcium slag contains ferrous iron oxide (fayalite) reacts quickly with Н2РO4 and heats the mixture to the required temperature for the appearance of astringent properties. Studies have shown that thanks to the use of orthophosphoric acid as a binder, it is possible to dispose of up to 85 % of non-ferrous metallurgy waste and at the same time obtain heat-resistant concretes with high physical and mechanical properties.
Revising Anthropocentrism of Technics in the Light of the 21st Century New Anthropological Models
Authors: Melnyk V. P , Lushch-Purii U. I
Published: September 2022

Purpose. To substantiate the definition of technics as the attributive characteristics of a human being and the necessity of its orientation towards human flourishing in the context of new anthropological models of the 21st century. Theoretical basis. Correlation between technics, technology and the human essence is examined. The role of technics is traced at different historical stages of human development. Negative and positive effects of digital technology development upon a contemporary human being is analysed in the light of new anthropological models: homo technologicus, homo digitalis and homo eudaimonicus. The content of a new worldview-value paradigm of defining goals of technology is outlined. Originality. Transformation of the role of technics correlates with value and worldview shifts in person’s understanding of his/her purpose in both natural and social worlds. Nowadays, philosophical analysis of anthropological dimension of technics and technology opens a horizon for seeking effective solutions in the face of the contemporary challenges and anti-utopian threats by means of focusing on the fact that, indeed, technological development is subordinate to the humanist goal that is flourishing, wellbeing and comprehensive development of a human being. Conclusions. The essence of technology reveals not through its functional but anthropogenic definitions in a sense of a source of institutionalization and in a sense of a source of realization of a human way of self-identification and self-objectification of human subjectivity. Technics/technology is the attributive characteristics of human essence and being: a human being is as much human as much he/she is a creator of technics. The purpose of technics is not to master the nature and to transform the world; technics is, above all, a tool of human self-improvement and self-creation through broadening the horizon of human capacities. The analysis of new modern anthropological models shows that it is the orientation of technology/technology towards human flourishing that is, on the one hand, a response to the existential demands of modern man, and on the other hand, a way of preventing future threats related to technological development.
ADVANTAGES OF CHOOSING THE RECONSTRUCTION OF INDUSTRIAL BUILDINGS INTO HOUSING IN CONDITIONS OF RECONSTRUCTION OF CITIES AFTER THE WAR
Authors: ARUTIUNIAN I. A. , PASTUKHOVA S. V. , SHCHEMELIEV А.V. , VERTEPNY I. I.
Published: September 2022

Purpose. Analysis of the main advantages of choosing the latest methods of renovation and reconstruction of industrial buildings into residential ones in the reconstruction of Ukrainian cities after the war based on existing domestic and foreign experience. Methodology. In Ukraine, in the current context of limited financial and logistical resources, the renovation and reconstruction of existing industrial buildings in destroyed cities and resettlement cities due to Russian aggression is an appropriate solution in terms of reducing the cost of new construction and reconstruction of industrial buildings. Along with the spread of modern methods of renovation and reconstruction of well-known Ukrainian and foreign companies in Ukraine, when planning the restoration of housing stock after the war, attention should be paid to the method of reconstruction of industrial buildings in loft-style housing. Identification of specific features of loft formation as new elements of reconstruction of industrial buildings into residential ones. Results. Analysis of domestic and foreign experience in renovation and reconstruction of industrial areas. It is revealed that depending on the tasks, different functional adaptation and direction of one or another industrial building or complex in residential, as well as their subsequent adaptation to the existing city system is possible. During the reconstruction of urban industrial areas, it is appropriate to use the loft style for reconstruction as economic, the feasibility of which is confirmed by world experience. Originality. Analysis of domestic and foreign experience in the renovation and reconstruction of industrial buildings for residential. Different approaches to the process of renovation of industrial territories are revealed and the principles of transformation of the existing industrial function into a public space are substantiated. Practical value. Technical, technological and organizational solutions allow the use of industrial buildings with their technological properties, which ensure the reliability of the operation of residential buildings. Analysis of the real state of industrial zones.