bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPROVE CRITICAL THINKING STUDENTS IN INDONESIA FOR NEW LEARNING MANAGEMENT SYSTEM
Authors: Iqbal Desam Girinzio  , Ahmad Ramadan  , Dimas Bagus Saputra  , Gadis Mustika
Published: July 2023

In Indonesian 4.0's goal for a knowledge-based economy, critical thinking skills have been given more weight. Given the seriousness of the problem, the researchers gathered a focus group of nine professionals in August 2017 and asked them to help create a new critical thinking education methodology. From this, the authors developed the "PUSCU Model," a five-focus management paradigm. Two subgroups of 69 students were formed using random cluster sampling. Two groups: one with 34 participants in traditional learning and one with 35 participants in experimental investigations. From November 2016 to February 2017, a 16-week test of the PUSCU model was carried out. A single Multivariate Analysis of Variance (MANOVA) was performed using the Statistical Package for the Sciences (SPSS) 21 software to ascertain any differences between the experimental and control groups. The outcomes showed that the study group's participants were content with the instructor's usage of the created learning materials and that, on the whole, they performed well in terms of critical thinking skills and academic performance.
Implementation of Information and Communication Technology in Management Learning System During the Covid 19 Pandemic
Authors: Putri Fadia Sasabila , Dermawanis Zega
Published: July 2023

This study examines the use of information technology in the management system of Indonesian higher education institutions. This could have been more optimal and evenly distributed in terms of hardware and management. This study is an international journal study. Input resource findings include visualizers/document cameras, computers, whiteboards, student-ready systems, and application programs. Output resources include projectors, interactive whiteboards, and displays. monitor, television, etc. Finally, other ICT devices include digital cameras, switchers, digital recorders, and other innovations. In short, inequalities in the infrastructure supporting the application of this technology in education and the need for better preparedness of human resources for the use of information and communication technologies in learning.
Industrial Revolution 4.0's Information Technology's Impact on the Growth of MSMEs in the Manufacturing Industries Sector
Authors: Ahmad Gunawan  , Rini Kartika Hudiono
Published: July 2023

The expansion of Micro, Small, and Medium Businesses (MSMEs) can have an impact on Indonesia's economic growth (MSMEs). Because MSME players lack the capacity to adapt new technology, new technology in the industrial era 4.0 is one of the barriers to the development of MSMEs in Indonesia.Due to the inability of MSME players to adapt new technologies, Indonesia. Sales information systems, social networking, and Google My Business are a few examples of technologies that MSME & SMEs may use to their advantage. These technologies can aid in sales, marketing, and customer communication. The aim of this study was to ascertain the extent to which MSMEs in Banyumas Regency employ information technology, including information systems, social media, and Google My Business. information technology's impact on Banyumas Regency MSMEs' success. The research approach employed is The findings demonstrated the significant growth of MSMEs using technologies like Tokopedia, Instagram, and Google Maps. Use of technologies like Tokopedia, Instagram, and Google Maps is expanding quickly. A combination of increased asset turnover and customer communication is made simpler. According to these findings, there is a high correlation between the two factors, suggesting that the usage of industrial information technology (IIT) 4.0 might influence MSMEs' development. in order to say that there is a substantial correlation between the two variables.
Komunikacja w radiu finansowanym przez społeczność. Przypadek internetowej stacji Radio 357
Authors: Chmielewski Piotr
Published: July 2023

Celem tekstu jest analiza modelu komunikacji z patronami Radia 357 – internetowej stacji radiowej finansowanej przez słuchaczy przy wykorzystaniu patronatu cyfrowego. Metodologia: dokonano jakościowej analizy treści znajdujących się na forum dla patronów rozgłośni. Na materiał empiryczny złożyło się 200 postów stacji, 21 081 komentarzy patronów oraz nagrania filmowe trwające łącznie 1050 minut. Analiza objęła okres od października 2020 r. do stycznia 2022 r. Wyniki i wnioski: przeprowadzona analiza wskazuje, że model komunikacji Radia 357 jest silnie uwarunkowany przez sposób finansowania rozgłośni. Stacja równolegle komunikuje się ze wszystkimi słuchaczami (za pośrednictwem strony internetowej oraz mediów społecznościowych) i moderuje odrębne fora dla najbardziej zaangażowanych patronów. Komunikacja wynika częściowo z indywidualnego modelu przyjętego przez rozgłośnię, częściowo zaś z ram i narzędzi narzuconych przez techniczne uwarunkowania platformy crowdfundingowej, na której prowadzona jest zbiórka. Wartość badawcza: analiza dostarcza wiedzy na temat charakterystyki oraz mocnych i słabych stron opisywanego modelu komunikacji. Co szczególnie ważne, zważywszy na ostatnie dekady dynamicznego rozwoju radiofonii, model ten istotnie różni się od dotychczasowego sposobu komunikowania tradycyjnych stacji radiowych.
Knowledge Broker Sebagai Mediasi: Merancang Perilaku Inovasi Dalam Mendukung Transformasi Digital Pada Ukm Di Sidoarjo
Authors: Larassaty Ayu Lucy
Published: July 2023

Small and Medium Enterprises (SMEs) have an important role for the economy of a country in order to increase productivity, competition and be able to open up business opportunities and create job opportunities. The phenomenon that occurs in the UKM environment in Sidoarjo is that UKM actors only focus more on tangible assets so they pay less attention to intangible assets. The purpose of this study is to find out the role and implementation of knowledge brokers to design innovative behavior in supporting digital transformation for SMEs in Sidoarjo. The research method uses the Field Research approach using qualitative research types. The data collection technique uses triangulation which consists of documentation, interviews, observation and surveys as well as recording archives. The results of the study explain the implementation of knowledge brokers to design innovative behavior in supporting digital transformation in SMEs in Sidoarjo, which is still  limited to Knowledge sharing where knowledge brokers are structured and designed as a bridge in providing information and consulting carried out by universities and organizational partners only in training activities and accompaniment. The role of knowledge brokers is very important in implementing strategies in utilizing company-owned resources to encourage digital transformation in SMEs, which can utilize digital technology to mediate interactions between stakeholders and SMEs who need capital in their businesses. expand business with investors who will invest to get a return on investment. This interaction increases digital literacy for SMEs and enhances the process of sharing and disseminating knowledge between organizations.
Readmission Rate of Outpatient Distal Radius Fixation Surgery with Brachial Plexus Block and Midline Pronator Quadratus Approach in the COVID-19 Era: A Retrospective Case Series Report in a Secondary Care Hospital in Thailand
Authors: Mahaisavariya Chantas , Puengtananukij Chuthamas , Siritongtaworn Anticha
Published: July 2023

Objective: To demonstrate the readmission rate after distal radius fixation surgery performed with a brachial plexus block and the midline pronator quadratus approach in an ambulatory manner in a secondary care hospital.
Materials and Methods: This retrospective study analyzed data on distal radius fracture patients treated with ambulatory surgery. The patients were enrolled from 1 January 2020 to 28 February 2022, which was during the COVID-19 pandemic. The primary outcome was the readmission rate within 30 days after the surgery. The secondary outcomes were complications, postoperative pain, radiographic outcome, and functional score. All patients were followed up for at least 1 year after the surgery.
Results: Thirty-one patients were enrolled in this study. Their mean age was 58.5 years, and the fractures were mainly caused by low-energy trauma. No postoperative complications were reported, and no readmission after surgery was observed. Overall radiographic parameters were in the acceptable range (radial inclination = 21.9, radial height = 10.26, volar tilt = 2.65, and ulna variance = 1.33). All patients returned to their preinjury statuses within 5 months.
Conclusion: Distal radius fixation surgery can be managed in an ambulatory manner with a low readmission rate, even in secondary care hospitals. This repair technique provides adequate soft tissue coverage of the volar radius plate while decreasing the risk of iatrogenic radial artery injuries.
Synthesis and Characterization of Eco-friendly, Biodegradable Plasticized Starch Nanocomposite using Graphene Oxide Nano-filler for Energy Storage Applications
Authors: Mollik S Islam , Mahmud E , Mina M F , Islam M R
Published: July 2023

In this study, environment-friendly, biodegradable nanocomposite has been fabricated using plasticized starch (PS) polymer and graphene oxide (GO) nanofiller. Biodegradable PS has been extracted from potatoes and a solution casting technique was used to synthesize PS/GO nanocomposite. The structural and surface morphological properties of the nanocomposite have been studied via FTIR and FESEM which demonstrate increased degree of interaction between the PS matrix and the GO nanofiller. The thermal properties of the nanocomposite showed that incorporation of GO improves the thermal stability of the nanocomposites. To study the energy storage capabilities of the PS/GO nanocomposites the electrochemical properties of the nanocomposites were as studied through cyclic voltammetry (CV), and galvanostatic charge-discharge (GCD) methods. The PS/GO nanocomposite showed improved capacitive performance with a specific capacitance of 112 F/g compared to that of pure starch (2.20 F/g) at a current density 0.1 mA/cm2. To study the effect of GO on the electrochemical properties of the nanocomposites, electrochemical impedance spectroscopy was performed and the corresponding graphs were simulated using simulation software. The incorporation of GO reduces the charge transfer resistance and thereby improve the capacitive performance. The improved electrochemical performance of the PS/GO nanocomposite can be further attributed to the large surface areas provided by the GO sheets allowing faster transport of electrolyte ions into the electrode. The result indicates that the PS/GO and nanocomposites may offer a promising route for the synthesis of bio-friendly and flexible energy storage devices.

J. of Sci. and Tech. Res. 4(1): 145-154, 2022
Dilencilik Kabahati
Authors: KOÇ Emin
Published: July 2023

Dilencilik kadim bir meslektir. Tarihsel süreç içerisinde karşılıksız edim elde etmek birçok dönemde toplumsal düzeni bozucu bir eylem olarak görülmemiştir. Dilencilik istisnaları olsa da günümüzde hukuk sistemlerinde toplumsal düzene aykırı bir faaliyet olarak düzenlenmiştir. Bu tercih sosyolojiden beslenmekte ve toplumsal düzene etkisine göre farklılaşabilmektedir. Bazı hukuk sistemleri bu eylemi serbest bırakırken bazı hukuk sistemleri suç, bazı hukuk sistemleri ise kabahat olarak düzenlemeyi tercih etmiştir. Bizim hukuk sistemimiz dilenciliği bir kabahat, dilendirmeyi (çocukları, beden veya ruh bakımından kendini idare edemeyecek durumda bulunan kimseleri dilencilikte araç olarak kullanmak) ise suç olarak düzenlemiştir. Bu tercihin bir yansıması olarak dilencilik Kabahatler Kanunu’nda düzenlenmiş ve kabahatlerin hukuki rejimine tâbi kılınmıştır. Kabahatlerin karşılığında öngörülen idari yaptırımlar ise idari işlem niteliğindedir. Kabahatler Kanunu, dilencilik ile hukuki esasların belirlenmesinde birçok konuda Türk Ceza Kanunu’na göndermede bulunmaktadır. Bu nedenle kabahatlerin hukuki rejiminin belirlenmesinde Türk ceza hukuku hükümleri uygulama alanı bulmaktadır. Özellikle hukuka uygunluk nedenleri ve kusurluluğu etkileyen haller Türk ceza hukuku hükümlerine göre belirlenmektedir. Ancak birçok husus doğrudan Kabahatler Kanunu’nda düzenlenmediği için uygulamada sorunlarla karşılaşılmaktadır.
İnternet Haber Sitelerinin Basın Kanunu ve Basın İş Kanunu Kapsamına Eklenmesinin Hüküm ve Sonuçları
Authors: EZER Burcu
Published: July 2023

Kitle iletişim araçlarında ortaya çıkan teknolojik gelişmeler, gazetecilik ve medya alanında köklü değişikliklere neden olmuştur. İnternet teknolojisiyle birlikte, geleneksel medya ve gazetecilik anlayışı biçim değiştirmiştir. Haberlere ulaşmak yönünden geleneksel gazeteciliğin yerini dijital uygulamalar almaya başlamıştır. Gazetecilik faaliyetleri başta olmak üzere çeşitli amaçlara hizmet eden çok sayıda dijital yayın platformu ortaya çıkmıştır. Medya ve gazetecilik alanında yaşanan bu gelişmeler, Türk basın mevzuatında bir süre kendine karşılık bulamamıştır. Dijital gazetecilik faaliyetleri, özellikle yükümlülük ve sorumluluğa ilişkin kanuni düzenlemelerin kapsamına girmeden; dijital yayın organları kapsamda çalışanlar ise yasal bir koruma altına
alınmadan çalışmalarını sürdürmüşlerdir. Nihayet 18.10.2022 tarihli Resmî Gazete’de yayımlanan 7418 sayılı Kanunla, 5187 sayılı Basın Kanununa ve 5953 sayılı Basın Mesleğinde Çalışanlarla Çalıştıranlar Arasındaki Münasebetlerin Tanzimi Hakkında Kanuna (Basın İş Kanununa) internet haber sitelerine ilişkin çeşitli hükümler eklenmiştir. Böylelikle öngörülen koşulları yerine getiren internet haber siteleri Basın Kanunu kapsamına; internet haber sitelerinde fikir ve sanat işlerinde çalışan kimseler ise Basın İş Kanununun kapsamına alınmıştır. Bu çalışmada, Basın Kanununa eklenen internet haber sitelerine ilişkin düzenlemeleri incelemek, Basın İş Kanununa eklenen “internet haber siteleri” ibaresinin kapsamına aldığı işyerleri ve gazetecilerin kimler
olduğunu tespit etmek; devamla, ilgili değişikliklerin güncel gelişmeler ışığında ihtiyaçları karşılamakta yeterli olup olmadığı hususunu incelemek amaçlanmaktadır.
Avrupa Birliği Dijital Hizmetler Yasası'nın Değerlendirmesi
Authors: ÇEVİK İpek
Published: July 2023

Dijital ekonominin giderek büyümesi ve dijital hizmet sağlayıcılarının sayısının artması ile birlikte bilgi toplumu önemli bir kavram haline gelmiştir. Bu değişen yapı nedeniyle Avrupa Birliği’nde, temel hakların ve kişilik haklarının korunması yanında tüketicinin korunması gibi hususlar açısından güvenli bir online mecra için belirli yükümlülüklerin netleştirilmesi gerekmiştir. Dijital Hizmetler Yasası (DSA) ile farklı hizmet sağlayıcılarının sorumluluklarının kapsamı ve yükümlülükleri belirlenirken, ortak pazarın da üye ülkeler açısından uyumlu hale getirilmesi hedeflenmiştir. Bu yenilikçi dijital pazarlar bakımından bir yandan fikir hürriyeti, medya çeşitliliği ve yeni girişimciler açısından özgürlükçü yapının korunması gerekirken; diğer yandan ise hukuka aykırı içerik kavramı kapsamında dezenformayon, mobbing ve tüketici ya da kullanıcıların aldatılması gibi hususlar karşısında da belirli sorumluluk esaslarının daha net bir şekilde belirlenmesi gerekliliği bu tüzüğün yürürlüğe girmesine etki etmiştir. İşbu makale, DSA uyarınca getirilen düzenlemelerin sistematiğini ortaya koymayı hedeflemektedir.
Perfil epidemiológico da população pediátrica com hipotireoidismo clínico e subclínico no Consórcio Intermunicipal de Saúde do Oeste do Paraná - CISOP
Authors: Favarim Giulia Maria Geron , Werncke Elaine , Moreira Vitória Marques , Silva Victória Beatrice Diniz , Pescador Marise Vilas Boas
Published: July 2023

A glândula tireoide é de suma importância para e desenvolvimento humano, devido à importante ação dos seus hormônios para o organismo humano. Em vista disso, as alterações tireoidianas afetam em demasiado os seres humanos, principalmente as crianças e adolescentes, visto que é um período que o organismo está em constante crescimento e desenvolvimento, assim sendo, deficiências na produção e/ou ação dos hormônios tireoidianos, acarretam diversos problemas, em especial nesse período. Por isso, essa pesquisa teve como objetivo avaliar o perfil epidemiológico dos pacientes pediátricos entre 0 a 12 anos, com diagnóstico de hipotireoidismo clinico e subclínico em tratamento em um serviço de endocrinologia pediátrica no Oeste do Paraná. Foram avaliadas 85 crianças, sendo o sexo feminino o mais acometido na amostra, o hipotireoidismo clínico adquirido foi o diagnóstico mais frequente, em sua grande parte devido a tireoidite de hashimoto. Além disso, a totalidade dos casos eram classificados como hipotireoidismo primário. Sendo alterações no resultado do TSH nos exames de rotina a principal queixa que motivou o encaminhamento para o serviço especializado. Também, pôde -se inferir que o exame físico no momento do diagnóstico foi bastante inespecífico, sendo em sua maioria sem alterações características da doença. Foi encontrado a Síndrome de Down como o quadro pré-existente mais associado ao diagnóstico de hipotireoidismo. Por fim, constatou-se que a maioria dos indivíduos estudados estavam em uso de levotiroxina como forma de tratamento do quadro diagnosticado.
Cienciarte: um caminho à transdisciplinaridade
Authors: Gustavo Luan da Silva , Moreira Leonardo Maciel
Published: July 2023

Este trabalho consiste em uma produção teórica que propõe a articulação de algumas ideias e referenciais com a finalidade de criar uma possibilidade à transdisciplinaridade. Para tanto, busca definições sobre transdisciplinaridade na literatura que se dedica a essa temática e tece pontes de possibilidade em articulação com o referencial teórico da Cienciarte. O objetivo é propor uma pedagogia cienciartística que parte do contexto da disciplina escolar ciências rumo a transposição das barreiras que limitam o espaço disciplinar. Para tanto, se apoia no referencial metodológico da Pesquisa Educacional Baseada em Artes (PEBA). Com essa articulação é possível apreender que a perspectiva cienciartística propõe o desmantelamento de aparentes dicotomias criadas historicamente na produção de conhecimento, tais como a própria ciência e a arte, a objetividade e subjetividade, bem como a razão e a sensibilidade. Para além disso, conjuntamente com a arte, principalmente as artes da cena, convida a pensar a multideterminação do corpo no processo de ensino e aprendizagem a partir da Educação Somática, o que consiste em uma perspectiva transdisciplinar sobre o corpo que aprende. Por fim vislumbra, a partir de uma consciência e criticidade alcançadas por uma pedagogia cienciartística, um caminho para a mobilização social e geração de uma vontade política de transformação da realidade vivida.
Analysis of the carbon neutral standard and its implementation in a dental clinic in Ecuador: A Review of the Literature
Authors: Prieto Veintimilla Cristina Stephany , Bernal-Merchán Bryam Andrés , Méndez-Calle Christian Geovanny , Tello-López Salomé , Bravo Calderón Manuel Estuardo
Published: July 2023

Introduction: The carbon neutral standard, or also known as carbon neutral or “zero net emissions” standard, aims to balance the greenhouse gas emissions released into the atmosphere with the elimination or compensation of the same amount of emissions. In many countries, this standard has been implemented with certain policies and measures to move towards carbon neutrality in different international agreements. Said policies include actions such as the promotion of renewable energies, energy efficiency, use of renewable materials, etc. Objective: to determine the importance of Carbon Neutral model in dental clinics. Materials and Methods: In this article, a review of the literature about the Carbon Neutral Standard and its impact on Companies and Dentistry was carried out, using scientific articles and other research documents from the Scopus, Google Scholar, Scielo databases. and the website of the Ministry of the Environment of Ecuador. Conclusion: The carbon neutral standard promotes environmental awareness and responsibility in companies, reducing emissions, energy and water consumption, and also minimizing the consumption of single-use plastics. Dental offices can be polluting, but the implementation of reusable supplies benefits the environment and saves money. In Ecuador, carbon neutral certifications endorsed by the National Environmental Authority can be obtained.
Cuidados de enfermagem no centro cirúrgico hospitalar em assistência perioperatório
Authors: Souza Denis Monteiro de , Alencar Lucas Viana de , Prata Rafaela Aparecida , Silva Regina Aparecida Capeli da , Minharro Michelle Cristine de Oliveira , Maigret Simone Buchignani
Published: July 2023

Objetivo: Identificar na literatura científica sobre os cuidados da enfermagem no centro cirúrgico hospitalar na assistência perioperatória. Método: Trata-se de uma revisão integrativa nas bases de dados Lilacs, BVS e SciELO. A coleta de dados deu-se em outubro de 2022, incluindo artigos do período compreendido entre 2017 a 2022. Para a coleta de dados dos estudos selecionados, utilizou-se um formulário padronizado contendo: identificação do estudo, autores, objetivo do estudo, resultados e recomendações, e conclusões. Resultados: Foram selecionados 572 artigos. Destes, apenas 4 artigos preencheram os critérios de inclusão. Dos 4 estudos selecionados, todos foram produzidos no Brasil no ano de 2017 à outubro de 2022. Os estudos incluídos nesta revisão destacaram os seguintes cuidados de enfermagem: visita pré e pós-operatória, cuidados de enfermagem na hipotermia, sistematização da assistência enfermagem. Conclusão: Este estudo contribuiu para auxiliar na atualização dos profissionais saúde onde os principais cuidados de enfermagem encontrados foram a visita pré e pós-operatória, cuidados de enfermagem na hipotermia, sistematização da assistência enfermagem.
Uso de tabaco por população ribeirinha em uma região amazônica do Brasil
Authors: Colli Ana Julia Mauri Delli , Vicente Laís Palma , Cerbarro Gabrielle Fernanda , Cabral Elizabeth Regina de Melo , Magalhães Ricardo Siufi
Published: July 2023

O tabagismo é a principal causa de morte em todo o mundo e está associado a uma série de doenças, configurando-se como um problema de saúde pública. O objetivo deste estudo foi descrever o consumo de tabaco de uma população ribeirinha do Arquipélago de Bailique/Amapá, acompanhada durante uma expedição de saúde, no ano de 2020. Estudo transversal realizado com 98 participantes residentes no Arquipélago de Bailique/Amapá. Foram aplicados questionários com questões abertas e fechadas sobre tabagismo e o Teste de Dependência à Nicotina de Fagerström com análise descritiva dos dados. Dos participantes do estudo, a maioria era do sexo feminino e 53,06% afirmaram não fumar. Nos participantes que usavam tabaco predominou a faixa etária de início do tabagismo dos 15 aos 20 anos, a escolaridade menor que 8 anos de estudo e o sexo masculino. A maioria dos participantes com menor renda nunca fumaram ou eram ex-tabagistas. Nenhum participante se autoavaliou como de nível elevado ou muito elevado de dependência. Necessita-se investir em ações de saúde voltadas para o público jovem solteiro com a finalidade de prevenir o tabagismo e seus malefícios.
Drivers of coral mortality in non-acute disturbance periods
Authors: Smith HA , Chen CCM , Pollock FJ , Re M , Willis BL , Bourne DG
Published: July 2023

Studies focused on understanding drivers of coral mortality often examine reef- or ecosystem-scale stressors and/or pulse events such as mass bleaching or disease outbreaks. While such work provides valuable information about large-scale changes to reef ecosystems, how stressors interact at the individual colony level across non-disturbance years is less understood. In this study, we tracked the fate of 400 platingAcroporacoral colonies from 2 mid- and 2 outer-shelf reefs for 18 mo and examined (1) temporal changes in the prevalence of stressors, (2) how stressors affected the survival of individual colonies, and (3) survival rates of colonies after contracting disease. We found that 35.5% of all colonies died within the 18 mo observation period, a period free from acute disturbances (e.g. cyclones, mass bleaching, crown-of-thorns starfish [CoTS] outbreaks). Despite its low prevalence, predation (byDrupellaspp. or CoTS) led to the greatest risk of complete mortality compared to corals that experienced no stressors (over 10-fold increased risk). Similarly, experiencing disease and physical injury (fragmentation, dislodgement) also increased the risk of complete mortality (~4-fold and ~2-fold, respectively). In contrast, while compromised health (i.e. bleaching, algal overgrowth) was common, this did not significantly increase the risk of colony mortality. Survival analysis of colonies with white syndrome showed that colonies exposed to stressors prior to contracting disease were 3 times more likely to die compared to colonies with disease alone. Our results highlight the complex interactions that occur among multiple stressors on coral reefs, even in non-disturbance years, and quantify the increased risk of mortality for colonies experiencing accumulated stressors.
NOVO ENSINO MÉDIO: ANÁLISE E PROJEÇÕES
Authors: Beloti Adriana , Grzeca Francini Carla , Bohrer Marcos
Published: July 2023

Esta entrevista com Daniel Cara, professor e pesquisador na área de educação, com o objtivo de debater o Novo Ensino Médio - NEM -, imposto pela reforma educacional materializada na Base Nacional Comum Curricular – BNCC -, de 2018.
atuação da Psicologia em casos de aborto resultante de gravidez por estupro de vulnerável
Authors: Hoepers Aline Daniele , Verde dos Santos Danielle
Published: July 2023

Este artigo tem por objetivo discutir a atuação das/os psicólogas/os nos mais diversos âmbitos profissionais (clínica, saúde pública, assistência social, segurança pública, sistema de justiça), bem como o posicionamento do Conselho Federal de Psicologia (CFP) diante das situações de gravidez/aborto resultante de estupro de vulnerável, no caso de menores de 14 anos. Trata-se de uma pesquisa de natureza teórica e qualitativa, fundamentada em levantamento bibliográfico em plataforma de dados, como LILACS/BVS (Literatura Latino-Americana e do Caribe em Ciências da Saúde/Biblioteca Virtual em Saúde), SciELO (Scientific Electronic Library Online) e PePSIC (Portal de Periódicos Eletrônicos de Psicologia) e, simultaneamente, em leitura de referências técnicas produzidas pelo órgão de classe profissional que versam sobre o tema direta ou indiretamente. A partir dos resultados encontrados, concluiu-se que, por mais que haja produção científica nacional sobre violência sexual infantojuvenil, ainda são incipientes os estudos na perspectiva do direito ao aborto nesses casos. Ademais, as orientações e os parâmetros para a atuação das/os psicólogas/os nessa demanda ainda são muito escassos, necessitando, assim, de pesquisas e de orientações técnicas do órgão da classe quanto ao manejo técnico e enfrentamento ao problema.
Enhanced bone regeneration via local low-dose delivery of PTH1-34 in a composite hydrogel
Authors: Zhang Shanyong , Ding Lei , Chen Gaoyang , Zhang Jiayin , Ge Wanbao , Qu Yuan
Published: July 2023

Introducing bone regeneration–promoting factors into scaffold materials to improve the bone induction property is crucial in the fields of bone tissue engineering and regenerative medicine. This study aimed to develop a Sr-HA/PTH1-34-loaded composite hydrogel system with high biocompatibility. Teriparatide (PTH1-34) capable of promoting bone regeneration was selected as the bioactive factor. Strontium-substituted hydroxyapatite (Sr-HA) was introduced into the system to absorb PTH1-34 to promote the bioactivity and delay the release cycle. PTH1-34-loaded Sr-HA was then mixed with the precursor solution of the hydrogel to prepare the composite hydrogel as bone-repairing material with good biocompatibility and high mechanical strength. The experiments showed that Sr-HA absorbed PTH1-34 and achieved the slow and effective release of PTH1-34. In vitro biological experiments showed that the Sr-HA/PTH1-34-loaded hydrogel system had high biocompatibility, allowing the good growth of cells on the surface. The measurement of alkaline phosphatase activity and osteogenesis gene expression demonstrated that this composite system could promote the differentiation of MC3T3-E1 cells into osteoblasts. In addition, the in vivo cranial bone defect repair experiment confirmed that this composite hydrogel could promote the regeneration of new bones. In summary, Sr-HA/PTH1-34 composite hydrogel is a highly promising bone repair material.
Enhanced performance of glycerol electro-oxidation in alkaline media using bimetallic Au–Cu NPs supported by MWCNTs and reducible metal oxides
Authors: de Gyves Josefina , Molina-Ruiz Luis G. , Rutz-López Erik , Ocampo Ana Lilia , Gutiérrez-Sánchez Alejandro , Munguía-Acevedo Nadia M. , Peña-Medina Frida , Esquivel-Peña Vicente
Published: July 2023

Electrochemical technologies for valorizing glycerol, a byproduct of biodiesel production, into electric energy and value-added chemical products continue to be technologically and economically challenging. In this field, an ongoing challenge is developing more active, stable, and low-cost heterogeneous catalysts for the glycerol electro-oxidation reaction (GlyEOR). This paper reports the influence of the preparation procedure, which involves intermatrix synthesis (Cu and Au NPs), followed by galvanic displacement (Cu–Au NPs) in previously functionalized multi-walled carbon nanotubes (MWCNTs). It also discusses the role of the supports, CeO2 NPs, and TiO2 NPs, obtained by a hydrothermal microwave-assisted procedure, on the electroactivity of a hybrid bimetallic Cu–Au/MWCNT/MO2 catalyst in the GlyEOR in alkaline media. The electrocatalytic behavior was studied and discussed in terms of structure, composition, and electroactivity of the synthesized materials, which were determined by Fourier-transform infrared spectroscopy (FTIR), flame atomic absorption spectroscopy (FAAS), transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), X-ray photoelectronic spectroscopy (XPS), and cyclic voltammetry (CV). In addition, the role of the oxidation states of Cu and Au in the as-prepared catalysts (Cu/MWCNT, Au/MWCNT, Cu–Au/MWCNT, Cu–Au/MWCNT–CeO2, and Cu–Au/MWCNT–TiO2) was demonstrated. It was concluded that the preparation method of metal NPs for the controlled formation of the most catalytically active oxidation states of Cu and Au, together with the presence of a conductive and oxophilic microenvironment provided by carbon nanotubes and facile reducible oxides in optimized compositions, allows for an increase in the catalytic performance of synthesized catalysts in the GlyEOR.
Magnesium production by molten salt electrolysis with liquid tin cathode and multiple effect distillation
Authors: Telgerafchi Armaghan Ehsani , Rutherford Madison , Espinosa Gabriel , McArthur Daniel , Masse Nicholas , Perrin Benjamin , Tang Zujian , Powell Adam C.
Published: July 2023

Low-cost clean primary production of magnesium metal is important for its use in many applications, from light-weight structural components to energy technologies. This work describes new experiments and cost and emissions analysis for a magnesium metal production process. The process combines molten salt electrolysis of MgO using MgF₂-CaF₂ electrolyte and a reactive liquid tin cathode, with gravity-driven multiple effect thermal system (G-METS) distillation to separate out the magnesium product, and re-use of the tin. Electrolysis experiments with carbon anodes showed current yield above 90%, while a yttria-stabilized zirconia solid oxide membrane (SOM) anode experiment showed 84% current yield. G-METS distillation is an important component of the envisioned process. It can potentially lower costs and energy use considerably compared with conventional magnesium distillation. Techno-economic analysis including detailed mass and energy balances shows that this electrolyte composition could lower costs by utilizing CaO, which is the primary impurity in MgO, as the Hall-Héroult process uses the sodium impurity in alumina. Analysis options include: raw material types (magnesite rock vs. brine or seawater), drying and calcining using electricity vs. natural gas, and carbon vs. SOM anode type. Using SOM inert anodes results in a cost premium around 10%–15%, mostly due to higher electrical energy usage resulting from membrane resistance, and reduces GHG emissions by approximately 1 kg CO₂/kg Mg product. Capital and operating cost estimates, and cradle to gate greenhouse gas (GHG) emissions analysis under several raw material and process technology scenarios, show comparable costs and emissions to those of aluminum production.
Race between virus and inflammasomes: inhibition or escape, intervention and therapy
Authors: Wu Nijin , Zheng Chunzhi , Xu Jiarui , Ma Shujun , Jia Huimin , Yan Meizhu , An Fuxiang , Zhou Yi , Qi Jianni , Bian Hongjun
Published: July 2023

The inflammasome is a multiprotein complex that further regulates cell pyroptosis and inflammation by activating caspase-1. The assembly and activation of inflammasome are associated with a variety of diseases. Accumulative studies have shown that inflammasome is a key modulator of the host’s defense response to viral infection. Indeed, it has been established that activation of inflammasome occurs during viral infection. At the same time, the host has evolved a variety of corresponding mechanisms to inhibit unnecessary inflammasome activation. Therefore, here, we review and summarize the latest research progress on the interaction between inflammosomes and viruses, highlight the assembly and activation of inflammosome in related cells after viral infection, as well as the corresponding molecular regulatory mechanisms, and elucidate the effects of this activation on virus immune escape and host innate and adaptive immune defenses. Finally, we also discuss the potential therapeutic strategies to prevent and/or ameliorate viral infection-related diseases via targeting inflammasomes and its products.
CERESMIP: a climate modeling protocol to investigate recent trends in the Earth's Energy Imbalance
Authors: Schmidt Gavin A. , Andrews Timothy , Bauer Susanne E. , Durack Paul J. , Loeb Norman G. , Ramaswamy V. , Arnold Nathan P. , Bosilovich Michael G. , Cole Jason , Horowitz Larry W. , Johnson Gregory C. , Lyman John M. , Medeiros Brian , Michibata Takuro , Olonscheck Dirk , Paynter David , Raghuraman Shiv Priyam , Schulz Michael , Takasuka Daisuke , Tallapragada Vijay , Taylor Patrick C. , Ziehn Tilo
Published: July 2023

The Clouds and the Earth's Radiant Energy System (CERES) project has now produced over two decades of observed data on the Earth's Energy Imbalance (EEI) and has revealed substantive trends in both the reflected shortwave and outgoing longwave top-of-atmosphere radiation components. Available climate model simulations suggest that these trends are incompatible with purely internal variability, but that the full magnitude and breakdown of the trends are outside of the model ranges. Unfortunately, the Coupled Model Intercomparison Project (Phase 6) (CMIP6) protocol only uses observed forcings to 2014 (and Shared Socioeconomic Pathways (SSP) projections thereafter), and furthermore, many of the ‘observed' drivers have been updated substantially since the CMIP6 inputs were defined. Most notably, the sea surface temperature (SST) estimates have been revised and now show up to 50% greater trends since 1979, particularly in the southern hemisphere. Additionally, estimates of short-lived aerosol and gas-phase emissions have been substantially updated. These revisions will likely have material impacts on the model-simulated EEI. We therefore propose a new, relatively low-cost, model intercomparison, CERESMIP, that would target the CERES period (2000-present), with updated forcings to at least the end of 2021. The focus will be on atmosphere-only simulations, using updated SST, forcings and emissions from 1990 to 2021. The key metrics of interest will be the EEI and atmospheric feedbacks, and so the analysis will benefit from output from satellite cloud observation simulators. The Tier 1 request would consist only of an ensemble of AMIP-style simulations, while the Tier 2 request would encompass uncertainties in the applied forcing, atmospheric composition, single and all-but-one forcing responses. We present some preliminary results and invite participation from a wide group of models.
Grice's Café: coffee, cream, and metaphor comprehension
Authors: Genovesi Chris
Published: July 2023

Some theorists argue that Grice's account of metaphor is intended as a rational reconstruction of a more general inferential process of linguistic communication (i.e., conversational implicature). However, there is a multi-source trend which treats Grice's remarks on metaphor as unabashedly psychological. The psychologized version of Grice's view runs in serial: compute what is said; reject what is said as contextually inappropriate; run pragmatic processing to recover contextually appropriate meaning. Citing data from reaction time studies, critics reject Grice's project as psychologically implausible. The alternative model does not rely on serial processing or input from what is said (i.e., literal meaning). I argue the serial processing model and its criticisms turn on a misunderstanding of Grice's account. My aim is not to defend Grice's account of metaphorper se, but to reinterpret auxiliary hypotheses attributed to him. I motivate two points in relation to my reinterpretation. The first point concerns the relationship between competence and performance-based models. To the second point: Several of the revised hypotheses make predictions that are largely consistent with psycho and neurolinguistic data.
Comparing alignment toward American, British, and Indian English text-to-speech (TTS) voices: influence of social attitudes and talker guise
Authors: Dodd Nicole , Cohn Michelle , Zellou Georgia
Published: July 2023

Text-to-speech (TTS) voices, which vary in their apparent native language and dialect, are increasingly widespread. In this paper, we test how speakers perceive and align toward TTS voices that represent American, British, and Indian dialects of English and the extent that social attitudes shape patterns of convergence and divergence. We also test whether top-down knowledge of the talker, manipulated as a “human” or “device” guise, mediates these attitudes and accommodation. Forty-six American English-speaking participants completed identical interactions with 6 talkers (2 from each dialect) and rated each talker on a variety of social factors. Accommodation was assessed with AXB perceptual similarity by a separate group of raters. Results show that speakers had the strongest positive social attitudes toward the Indian English voices and converged toward them more. Conversely, speakers rate the American English voices as less human-like and diverge from them. Finally, speakers overall show more accommodation toward TTS voices that were presented in a “human” guise. We discuss these results through the lens of the Communication Accommodation Theory (CAT).
Hypoxia-associated genes predicting future risk of myocardial infarction: a GEO database-based study
Authors: Li Shaohua , Zhang Junwen , Ni Jingwei , Cao Jiumei
Published: July 2023

Background

Patients with unstable angina (UA) are prone to myocardial infarction (MI) after an attack, yet the altered molecular expression profile therein remains unclear. The current work aims to identify the characteristic hypoxia-related genes associated with UA/MI and to develop a predictive model of hypoxia-related genes for the progression of UA to MI.

Methods and results

Gene expression profiles were obtained from the GEO database. Then, differential expression analysis and the WGCNA method were performed to select characteristic genes related to hypoxia. Subsequently, all 10 hypoxia-related genes were screened using the Lasso regression model and a classification model was established. The area under the ROC curve of 1 shows its excellent classification performance and is confirmed on the validation set. In parallel, we construct a nomogram based on these genes, showing the risk of MI in patients with UA. Patients with UA and MI had their immunological status determined using CIBERSORT. These 10 genes were primarily linked to B cells and some inflammatory cells, according to correlation analysis.

Conclusion

Overall, GWAS identified that the CSTF2F UA/MI risk gene promotes atherosclerosis, which provides the basis for the design of innovative cardiovascular drugs by targeting CSTF2F.
Cardiac “hypertrophy” phenotyping: differentiating aetiologies with increased left ventricular wall thickness on echocardiography
Authors: Ferkh Aaisha , Tjahjadi Catherina , Stefani Luke , Geenty Paul , Byth Karen , De Silva Kasun , Boyd Anita C. , Richards David , Mollee Peter , Korczyk Dariusz , Taylor Mark S. , Kwok Fiona , Kizana Eddy , Ng Arnold C. T. , Thomas Liza
Published: July 2023

Aims

Differentiating phenotypes of cardiac “hypertrophy” characterised by increased wall thickness on echocardiography is essential for management and prognostication. Transthoracic echocardiography is the most commonly used screening test for this purpose. We sought to identify echocardiographic markers that distinguish infiltrative and storage disorders that present with increased left ventricular (LV) wall thickness, namely, cardiac amyloidosis (CA) and Anderson–Fabry disease (AFD), from hypertensive heart disease (HHT).

Methods

Patients were retrospectively recruited from Westmead Hospital, Sydney, and Princess Alexandra Hospital, Brisbane. LV structural, systolic, and diastolic function parameters, as well as global (LVGLS) and segmental longitudinal strains, were assessed. Previously reported echocardiographic parameters including relative apical sparing ratio (RAS), LV ejection fraction-to-strain ratio (EFSR), mass-to-strain ratio (MSR) and amyloidosis index (AMYLI) score (relative wall thickness × E/e′) were evaluated.

Results

A total of 209 patients {120 CA [58 transthyretin amyloidosis (ATTR) and 62 light-chain (AL) amyloidosis], 31 AFD and 58 HHT patients; mean age 64.1 ± 13.7 years, 75% male} comprised the study cohort. Echocardiographic measurements differed across the three groups, The LV mass index was higher in both CA {median 126.6 [interquartile range (IQR) 106.4–157.9 g/m2]} and AFD [median 134 (IQR 108.8–152.2 g/m2)] vs. HHT [median 92.7 (IQR 79.6–102.3 g/m2), p < 0.05]. LVGLS was lowest in CA [median 12.29 (IQR 10.33–15.56%)] followed by AFD [median 16.92 (IQR 14.14–18.78%)] then HHT [median 18.56 (IQR 17.51–19.97%), p < 0.05]. Diastolic function measurements including average e′ and E/e′ were most impaired in CA and least impaired in AFD. Indexed left atrial volume was highest in CA. EFSR and MSR differentiated secondary (CA + AFD) from HHT [receiver operating curve–area under the curve (ROC-AUC) of 0.80 and 0.91, respectively]. RAS and AMYLI score differentiated CA from AFD (ROC-AUC of 0.79 and 0.80, respectively). A linear discriminant analysis with stepwise variable selection using linear combinations of LV mass index, average e′, LVGLS and basal strain correctly classified 79% of all cases.

Conclusion

Simple echocardiographic parameters differentiate between different “hypertrophic” cardiac phenotypes. These have potential utility as a screening tool to guide further confirmatory testing.
Left atrial enlargement and high uric acid level are risk factors for left atrial thrombus or dense spontaneous echo contrast in atrial fibrillation patients with low to moderate embolic risk assessed by CHA2DS2-VASC score
Authors: Tan Chao-Di , Liu Juan-Zhang , Zheng Yu-Ping , Li Zong-jian , Zhou Shu-Xian
Published: July 2023

Aims

To investigate the correlation and predictive value of left atrial diameter and blood uric acid levels with the occurrence of left atrial thrombus or dense spontaneous echo contrast in atrial fibrillation patients with low to moderate CHA2DS2-VASc scores.

Methods and results

A total of 849 inpatients diagnosed with atrial fibrillation who had low to moderate CHA2DS2-VASc scores and complete transesophageal echocardiography were included in this study. Among them, 66 patients had left atrial thrombus or dense spontaneous echo contrast. When different models were used to correct other known risk factors, acid levels and abnormal left atrial diameter were identified as additional risk factors for left atrial thrombus or dense spontaneous echo contrast. The incidence of left atrial thrombus or dense spontaneous echo contrast was higher in patients with abnormal serum uric acid levels than in the control group (12.4% vs. 5.6%, p < 0.05), and this difference persisted after correcting the baseline data with propensity score matching (10.6% vs. 4.1%, p < 0.05). Abnormal left atrial diameter was another risk factor suggested by regression analysis, with an increased incidence of left atrial thrombus or dense spontaneous echo contrast in the abnormal left atrial diameter group compared to the control group, both before (18.0% vs. 3.5%, p < 0.05) and after (15.5% vs. 5.2%, p < 0.05) propensity score matching. The best predictive value was obtained by adding both abnormal serum uric acid levels and abnormal left atrial diameter.

Conclusion

Left atrial enlargement and high uric acid levels increase the risk of left atrial thrombus or dense spontaneous echo contrast in atrial fibrillation patients with low to moderate CHA2DS2-VASc scores.
The impact of maternal diabetes on the future health and neurodevelopment of the offspring: a review of the evidence
Authors: Rodolaki Kalliopi , Pergialiotis Vasilios , Iakovidou Nikoleta , Boutsikou Theodora , Iliodromiti Zoe , Kanaka-Gantenbein Christina
Published: July 2023

Maternal health during gestational period is undoubtedly critical in shaping optimal fetal development and future health of the offspring. Gestational diabetes mellitus is a metabolic disorder occurring in pregnancy with an alarming increasing incidence worldwide during recent years. Over the years, there is a growing body of evidence that uncontrolled maternal hyperglycaemia during pregnancy can potentially have detrimental effect on the neurodevelopment of the offspring. Both human and animal data have linked maternal diabetes with motor and cognitive impairment, as well as autism spectrum disorders, attention deficit hyperactivity disorder, learning abilities and psychiatric disorders. This review presents the available data from current literature investigating the relationship between maternal diabetes and offspring neurodevelopmental impairment. Moreover, possible mechanisms accounting for the detrimental effects of maternal diabetes on fetal brain like fetal neuroinflammation, iron deficiency, epigenetic alterations, disordered lipid metabolism and structural brain abnormalities are also highlighted. On the basis of the evidence demonstrated in the literature, it is mandatory that hyperglycaemia during pregnancy will be optimally controlled and the impact of maternal diabetes on offspring neurodevelopment will be more thoroughly investigated.