bluuebunny/crossref_metadata_2025 huggingface dataset:
The Actual Challenges and Efficient Ways of Translating Metaphore, Metonemy, Synechdoche In Literary Works
Authors: Nilufar Bafoyeva
Published: November 2024

Translating stylistic devices like metaphor, metonymy, and synecdoche in literary works indeed poses significant challenges. Each device carries layers of meaning that are often tied to cultural contexts and linguistic nuances. Here’s a detailed look at the challenges involved and some effective strategies for translation.
Concepts and Principles Of Teaching Foreign Languages In Primary Education: A Theoretical Approach
Authors: Abdullayeva Madinabonu
Published: November 2024

This article explores the fundamental concepts and principles of teaching foreign languages in primary education, emphasizing its role in fostering cognitive and social skills in young learners. Additionally, the article outlines essential teaching principles, such as age-appropriateness, maintaining motivation, and creating a natural learning environment, effectiveness of game-based learning and examines challenges in early language instruction, including resource limitations and lack of trained educators, offering practical recommendations to address these issues and improve foreign language education outcomes in primary education.
Perspektif Staf dan Tamu Hotel Terhadap Pengaplikasian Chatbot pada Kantor Depan Hotel di Gading Serpong
Authors: Hidayat Victoriano , Setiawan Budi
Published: November 2024

Gading Serpong mengalami perkembangan yang sangat pesat dan menjadi titik kumpul untuk berbagai acara atau kegiatan tertentu. Perkembangan tersebut perlu dimanfaatkan seiring dengan proses digitalisasi dan revolusi industri 5.0 yang telah memberikan dampak yang signifikan terhadap bidang teknologi informasi. Hadirnya kecerdasan buatan yaitu Artificial Intelligence (A.I.) menciptakan suatu program yang memungkinkan untuk membalas pesan secara otomatis 24 jam tanpa henti khususnya dalam dunia perhotelan yaitu chatbot. Metode yang umum digunakan adalah Decision Tree-Based (DTB). Chatbot perlu diimplementasikan pada hotel-hotel di Gading Serpong khususnya pada layanan front office hotel untuk dapat membantu mengatasi permasalahan yang muncul pada saat High Season atau Peak Hour seperti panggilan tamu yang tidak terjawab. Penelitian ini merupakan penelitian kualitatif dan menggunakan teknik observasi, wawancara sebagai pengumpulan data. Data yang terkumpul selanjutnya akan diolah dengan menggunakan model Miles dan Huberman. Hasil penelitian ini menjelaskan cara kerja chatbot dengan metode DTB, manfaat penggunaan chatbot oleh hotel-hotel di Gading Serpong, perspektif staf dan tamu hotel, serta tantangan dan solusi terhadap pengaplikasian chatbot pada layanan kantor depan hotel di gading serpong.
The Analysis of Knowledge to the Skill of Health Cadres in Carrying Out the Early Detection of Pneumonia in Sick Children in the Working Area of Public Health Centre, Belimbing Padang City
Authors:   Lectures of The Nursing Department, Ministry of Health Polytechnic, Padang, Tisnawati Tisnawati , Suhaimi Suhaimi ,   Lectures of The Nursing Department, Ministry of Health Polytechnic, Padang, Muchtar Murniati ,   Lectures of The Nursing Department, Ministry of Health Polytechnic, Padang, Delima Delima ,   Lectures of The Nursing Department, Ministry of Health Polytechnic, Padang, Herwati Herwati ,   Lectures of The Nursing Department, Ministry of Health Polytechnic, Padang
Published: November 2024

Under-five year children death in Indonesia due to pneumonia are 32 per 1000 live birth. Data in 2018 in West Sumatra, the prevalence of ISPA was 5%, pneumonia rose to 2.5%, in the city of Padang in 2018, the number of pneumonia sufferers were 3,196 under-five year children (3.91 %). In public Health Center, Belimbing the cases of respiratory tract infection is ranked first among the ten most common diseases (53%). The aim of the research is to analyze the knowledge to the skill of cadres regarding the early detection of pneumonia in under five year children. This research design is a cross-sectional study. The population in this research were 55 respondents. Data collection used questionnaires and observation sheets. Data processing was used by editing, coding, entrying and cleaning. Univariate analysis was made in frequency distribution in percentages, and bivariate analysis used the Chi square test (CI 95%). The research results showed that there is a relationship between knowledge to health cadres’s skill, with p-value (0.004). It is hoped that cooperation will continue the program for sustainability and conduct continuous evaluation to reduce pneumonia.
Perceptions of Local and Traditional Government Leaders for Enhancing Community Development
Authors: Dotsey Andrews , Kwapong Olivia , Addae David , Fuseini Issahaka
Published: November 2024

Purpose: There are two key governance forms in Ghana, specifically traditional governance and democratic governance. Accelerating development in the local communities requires effective collaboration and the fusion of the two governances divide to harness the unique capabilities and opportunities embedded within each paradigm. The perceptions hold by local and traditional leaders about each other is fundamental to collaborative efforts. Such perceptions speak to the psychosocial, convictional and behaviour of local leaders.
Methodology: This study through a field survey samples the views of two leadership divide about each other in terms of their ability to drive positive change in the community to drive accelerated community development. The study was conducted among three select districts specifically, the Accra Metropolis, Kumasi Metropolis and the Tamale Metropolis using key informant interviews, and focus group discussions to gather the data. The data was analysed using thematic analysis.
Findings: The findings of the study indicated that there are shared perceptions of strengths of both systems of governance for developing local communities. The traditional leaders are seen to be strong on cultural legitimacy, moral authority, communication competence, and historical knowledge, all of which helps in social mobilization within the local communities. The local government leaders were found to exercise strength in the areas of access to money and resources, legal authority, and enforcement authority.
Unique Contribution to Theory, Practice and Policy: We conclude that there are opportunities to harness each of these strengths such that a successful fusion of local and traditional systems of government will lead transformative leadership for sustainable local development.
WEATHERING THE STORM: A SYSTEMATIC LITERATURE REVIEW OF WEATHER STATIONS’ OBSERVATIONAL PRACTICES
Authors: ESPERANZA HILARIO DE GUZMAN
Published: November 2024

This literature review examines the accuracy, error frequency, and the impact of workload and decision-making on the weather observations made by PAGASA synoptic station personnel in the Cordillera Administrative Region (CAR). The accuracy of weather data collected by PAGASA is critical for reliable forecasting and timely decision-making in various sectors, including agriculture, disaster management, and transportation. The review highlights key factors influencing data accuracy, such as instrument calibration and human error. Studies show that while the accuracy of weather observations is generally high, occasional discrepancies occur, often due to technical issues or human mistakes in data recording, especially during extreme weather events. The review also explores the frequency of errors in weather observation data. Research indicates that errors are infrequent, but they are more likely to occur during severe weather conditions or in cases of equipment malfunctions or power failures. Although external factors can occasionally disrupt the data collection process, the overall frequency of errors remains relatively low. Furthermore, the impact of workload and decision-making on the accuracy of observations is discussed. Heavy workloads during peak weather seasons and the pressure of rapid decision-making during extreme weather events were found to contribute to an increased likelihood of errors. Studies emphasize the importance of managing workload and decision-making stress to maintain the quality of data. The review concludes by suggesting that further research, training, and technological improvements are needed to enhance the accuracy and reliability of weather observations in PAGASA synoptic stations in CAR.
Factors Influencing the Multi-Grade Instruction and Work Performance of the Multi-Grade Teachers in the Schools Division of Borongan City
Authors: Apar-Gesoyot Jessa , Rapada, Jr Virgilio P.
Published: November 2024

This study investigated the factors influencing the multi-grade instruction and work performance of the multi-grade teachers in the Schools Division of Borongan City. Specifically, it aimed to determine the factors influencing multi-grade instruction in terms of the following indicators such as personal-related factors, school-related factors, learner-related factors, and community-related factors; determine the work performance of the multi-grade instruction and assess if there is a significant relationship between the factors influencing multi-grade instruction and the work performance of the multi-grade teachers. A descriptive and correlational research design was employed in this study. This study was conducted in the Schools Division of Borongan City. Specifically, this study catered to only forty-one (41) multi-grade teachers for the School Year 2023-2024, chosen through purposive sampling via total enumeration. The study utilized two sets of survey questionnaires as research instruments. In finding out the factors influencing multi-grade instruction, the researcher adapted the survey questionnaire from the study of Haramain (2018); while for the work performance of the multi-grade teachers, the researcher asked for the final rating of the teachers’ IPCRF for three consecutive years. The study revealed that multi-grade teachers’ instruction highly influenced personal-related factors. School-related factors, learners-related factors, and community-related factors showed a very high influence on teachers in multi-grade instruction based on the respondents’ responses. The consistently high percentage of multi-grade teachers performed at the “very satisfactory” level across all three years. Moreover, a small percentage of multi-grade teachers achieve an “outstanding” level of work performance. A relatively low percentage of multi-grade teachers are categorized as “satisfactory” each school year. Work performance for School Year 2020-2021 and 2021-2022 revealed that personal and community-related factors revealed to be statistically significant and statistically insignificant for school and learner-related factors. Meanwhile, for the School Year 2022-2023, it shows that only community-related factors seemed to be statistically significant, while the rest of the factors, such as the personal, school, and learner-related factors, were statistically insignificant
Exploring Digital Curation’s Role in Enhancing Student Engagement in Open Distance Learning among Gen Z
Authors: Mohamed Nik Rozilaini Wan , Mahmud Nurazree , Arham Ahmad Fadly
Published: November 2024

This qualitative case study investigates how digital curation impacts student engagement in Open Distance Learning (ODL) environments, focusing on Gen Z learners. Through semi-structured interviews and participant observations, the study explores how behavioral, cognitive, emotional, and agentic engagement patterns are shaped by curated digital content. The findings offer insights into how digital curation supports the unique learning preferences of Gen Z, a generation known for its comfort with technology and need for interactive, engaging content. Recommendations are provided for educators aiming to optimize digital curation strategies to enhance academic engagement and success among Gen Z learners. This qualitative case study examines how digitally curation course materials influences student participation in Open Distance Learning education programs aimed at Generation Z. This study applies semi-structured interviews and observations explored how Gen Z involvement was gathered by curated digital resources. The finding identifies the insights emerged around how digital curation accommodates Generation Z’s strengths with technology and necessity for interactive content that maintains focus. The finding recommendations advise educators to maximize digital selection approaches to heighten academic commitment and accomplishment among learners from Generation Z.
Stress-Strength Reliability Bayesian of Generalized Exponential-Poisson Distriution for Complete Data
Authors: Nada S Karam  , Hajer M AbdAwon
Published: November 2024

In this paper, a Bayesian analysis is made to estimate the Reliability of two stress-strength model systems. First: the reliability  of one component strengths X under stress Y. Second: reliability  of one component strength under two stresses. Where X and Y are independent Generalized Exponential-poison random variables with (α, λ, θ) and (β, λ, θ), parameters respectively. The analysis is concerned based on complete data samples using gamma prior under eight different loss functions (Quadratic, Squared error, Weighted, Linear exponential, precautionary, De Groot, Entropy, and non-Linear exponential). The estimators are compared by Mean squared error criteria due to a simulation study and find that the best performance of the estimators found in order as (Quadratic, Weighted, Linear exponential and non-Linear exponential.
Deposition Fe2O3 Doping Barium Ferrites Thin Films on Glass without Annealing and Study their Microwave Properties
Authors: Ali J. Yousif  , Kadhim J. Kadhim
Published: November 2024

The series of ferrites samples doped by Barium with general formula Barium nitrate Ba(NO3)2  was prepared,  The Chemical Spray Pyrolysis (CSP) technique method of preparation of thin films for Iron (III) nitrate  Fe(NO3)3.9H2O  at (X) values ranging from 0.0 to 7%, where (X) represents the proportion of Barium in ferrite. doping, as well as the factors affecting the preparation of these films, which were deposited on glass Many techniques are used to analyze and test the prepared, sintering temperature has been used which is (450ºC temperature the substrate), to determine the effect of sintering temperature on the final specifications of the samples, (Network analyzer device) has been used to study the microwaves absorption in the range of (X- band) with a frequency range (8 -12.5 GHz). Also X-ray diffraction analysis (XRD) has been used to determine the crystal structure and purity of the prepared samples and to calculate the average grain size and micro strain, The samples were examined using a scanning electron microscope device to evaluate the crystal size and to see distribution style after the sintering process, Also the resonance peaks for all types of ferrite appeared at frequencies(9.350, 11.825, and 11.983)
Enhancement of TiO2 nanostructure for super capacitors Application
Authors: Rofaida M. Mustaf  , Qahtan N. Abdullah  , Iftikhar M. Ali
Published: November 2024

In this paper, TiO2 nanoparticles were prepared, in addition to chemically synthesized PAni compounds by oxidation method, added 15% of PAni to 10%of TiO2 to investigate super capacitance properties of TiO2 after PAni addition.  The structural properties of XRD and FE-SEM for the two materials were studied separately and then for composite. In order to understand the optical properties, UV-Vis spectrometer was used, where the energy gap of titanium oxide was calculated and was 4eV, as well as the polymer material was 4.6eV.  The capacity characteristics were also studied and good results were shown for the super capacitors.
Enhancement of Geothermal Energy in Rationalization of Electrical Power Consumption
Authors: Nidal S. Mohammed  , Ahmed F. Atwan  , Naseer K. Kasim
Published: November 2024

Iraq is rich in renewable energy resources while suffering from a severe shortage of electrical power supplying hours, accordingly the current study aims at design a ground source heat pump system (two-ton compression air conditioning systems) utilizing from shallow subterranean energy in order to rationalization electricity consumption. The results refer to huge contribution of shallow geothermal energy source in rationalization in electric power consumption. The results show a doubling in coefficient of performance and reduction in active electric power to more than the half of its original value.
On Some New Types of Partitions Associated with es -Abacus
Authors: E.F. Mohommed
Published: November 2024

In this work a new method called Sequences method used to establish new diagram which called  -abacus with four different movements, namely . Then, a new rule constrict to find es-abacus diagram constrict in case  from -abacus diagram in case . Further,  several examples are given to illustrate the new method.
Study the optical properties and FTIR spectroscopy of polyvinyl alcohol doped by potassium permanganate films
Authors: H.H. Mohammed and T.J. Alwan
Published: November 2024

The casting method was used to prepared pure polyvinyl alcohol PVA and doped by potassium permanganate (PVA/KMnO4) films, with different weight ratios (2, 4, 6, 8) Wt% of potassium permanganate in order to investigate the impact of potassium permanganate on the optical properties and FTIR spectroscopy of the prepared films. Infrared spectra in the wavenumber range (600-2000) cm-1 used to study the effect of doped on the functional groups of polyvinyl alcohol. UV-VIS spectroscopy was used to study the optical properties for the samples and based on these spectra, the optical energy gap was calculated, which was in the range 3.2 eV for the pure films and decreases with increasing the doping ratio of potassium permanganate to be 2.62 eV. The absorption coefficient, extinction coefficient, refractive index, the dielectric constant and optical conductivity were also studied under the influence of doping ratios.
Comparison of the Outcome Between Ligasure and Conventional Suture tie Techniques in Patients Undergoing Thyroidectomy
Authors: Muhammad Rizwan Anwar  , Muhammad Hussnain Iqbal  , Ghulam Hassan
Published: November 2024

Objective: To compare the outcome between ligasure and conventional suture tie techniques in patients undergoing thyroidectomy.
Study setting and duration: This study was conducted in the department of general surgery, DHQ hospital Dera Ghazi Khan, over a period of one year from September 2022 to September 2023.
Subject and methods: This randomized controlled study was conducted on 60 patients divided in two groups, group a (ligasure technique and group b (conventional suture technique) having age 30-65 years either male or female gender presented to undergo thyroidectomy. Patients undergoing chemotherapy, recurrent cases and bleeding diathesis (INR > 1.5) were excluded. The participants were randomly assigned to group A and group B through draws method using sealed opaque envelopes. All the surgical procedures were performed as per institutional protocol by consultant surgeon with ? 5-year post-fellowship experience. All the patients received anesthesia as per hospital protocol.
Results: This study was conducted on 60 patients divided in two groups equally, group a (ligasure technique) and group b (conventional technique). The mean age in group A was 47.80±11.54 years and 44.83±10.38 years in group B. among patient in group A 10 (33.3%) patients had total thyroidectomy while 20 (66.7%) patients had subtotal thyroidectomy and in group B 12 (10%) patients had total thyroidectomy while 18 (60%) patients had subtotal thyroidectomy. Group A had significantly shorter operative time (62.07±3.09 mins vs 69.70±3.18 mins, P = 0.0001) as compared to group B. According to the comparison of total blood loss between both groups, group A had significantly lower blood loss (56.27±2.50 ml vs 68.57±2.92) as compared to group B.
Conclusion: It can be concluded that ligasure technique had better outcomes as compared to conventional suture tie technique. The mean operative time and blood loss was significantly lower in ligasure technique as compared to conventional suture technique.
Keywords: Conventional technique, ligasure, mean operative time, post-operative blood loss, thyroidectomy
Comparative Efficacy of Metformin and Liraglutide in Pediatric Type 2 Diabetes
Authors: Aamir Naseem  , Malik sikandar Mehmood  , Roshaan Bashir  , Maria Ilyas  , Muhammad Tariq  , Abdul Azeem
Published: November 2024

Objective:  To assess the safety and efficacy of liraglutide versus metformin in patients with type 2 diabetes in the pediatric age group
Methods: This was an open-label, 24-week randomized controlled experiment. Three to sixteen-year-old Children with type 2 diabetes were randomized to receive either metformin or liraglutide. The main outcome was the variation in HbA1c at week 24. The research was completed by 150 subjects in all, and analysis was done on this cohort.
Results: At week 24, the metformin group had a decrease in HbA1c (p value = 0.001), going from 8.0 ± 0.7% to 7.2 ± 0.8% (53 ± 2 mmol/mol), and in the liraglutide group (p = 0.001), going from 7.7 ± 0.7% to 7.1 ± 0.6% (52 ± 2 mmol/mol). However, the group comprised liraglutide grasped maximum decline more quickly as compared to metformin group. The incidence of hypoglycemia and other parameters studied did not differ significantly across the groups.
Conclusion: During a 24-week period, individuals with T2DM treated with liraglutide and metformin alone had comparable reductions in HbA1c, with no discernible differences in other metrics.
АБАЙ ОБЛЫСЫ, ҮРЖАР АУДАНЫ «АҚМАРАЛ» ШАРУА ҚОЖАЛЫҒЫНДА ЖЫЛҚЫНЫҢ АЛЬМОНЕЛЛЕЗДІК ІШ ТАСТАУЫН АЛДЫН АЛУ ІС-ШАРАЛАРЫ
Authors: М. Қ. Батырбеков
Published: November 2024

Бұл мақалада Үржар ауданы аумағында орналасқан «Ақмарал» шаруа қожалығында жылқының сальмонеллездік іштастауын алдын алу іс-шараларын ұйымдастыру бойынша зерттеу нәтижелері берілген. Үржар ауданы бойынша жылқылардың сальмонеллездік іш тастауы бойынша эпизоотологиялық жағдайын анықталып, жылқыларды сальмонеллезге қарсы вакцинациялау жұмысын жүргізу нәтижелері жарияланып отыр. «Ақмарал» шаруа қожалығының аумағында эпизоотияға қарсы жүргізілетін ветеринариялық іс-шараларға қарамастан, ауыл шаруашылығы жануарларының сальмонеллезі бойынша қолайсыз пункттер мезгіл-мезгіл тіркеледі. Эпизоотологиялық кезеңде немесе эпизоотиялық процестің қарқындылығының төмендеуінде сальмонеллалар ауыл шаруашылығы жануарларының, синантропты және жабайы фаунаның популяцияларында айналымын жалғастыруда. Сонымен қатар, жұқпалы аурудың стационарлық көрінісі табиғи-климаттық және әлеуметтік-экономикалық факторлардың әсерінен болуы мүмкін. Қолайсыз факторлардың әсері организмнің табиғи төзімділігінің төмендеуіне, соның ішінде нақты профилактиканың тиімділігіне әкеледі. Сальмонеллез кезіндегі эпизоотиялық процестің шиеленісіне факторлардың әсерін бағалау осы ауру бойынша Үржар ауданы аумағының эпизоотиялық салауаттылығын қамтамасыз ету үшін ветеринариялық іс-шараның қолданыстағы жүйесін жетілдіруге мүмкіндік береді. В-0147 Salmonella abortus equi Е-841 штаммынан тірі вакцинамен жүйелі егу жануарларды сальмонеллез этиологиясының түсіктерінен қорғауды қамтамасыз етеді, құлындардың шығымдылығын, сүт өнімділігін арттырады, нәтижесінде шаруашылықтар үлкен экономикалық әсер алады. Вакцина 100 % жағдайда тәжірибелі биелерді сальмонеллалық түсік жасатудан қорғайды. Егілген жануарлардың иммунитеті бір жыл бойы сақталады. Кілтті сөздер: Salmonella abortus equi, сальмонеллездік іш тастау, штамм, вакцинациялау, профилактика.
Formulation and evaluation of novel orodispersible tablet by drug-drug solid dispersion of metoprolol tartrate and hydrochlorothiazide
Authors:   https://www.connectjournals.com/pages/articledetails/toc039043, Salim Shah Afrin
Published: November 2024

This study investigates the effect of a novel drug-drug solid dispersion approach on the dissolution of hydrochlorothiazide in a fixed-dose combination with metoprolol tartrate. Solid dispersions of hydrochlorothiazide and metoprolol tartrate (12.5 mg: 25 mg) were prepared using the solvent evaporation technique. These dispersions were characterized by differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR). The prepared solid dispersions, along with selected excipients, were compressed into orodispersible tablets and evaluated for precompression and post compression parameters. The solubility of hydrochlorothiazide was observed to increase with the concentration of metoprolol tartrate, as demonstrated by phase solubility studies and comparative solubility studies. Stability studies on the tablets indicated no significant changes in disintegration time, dissolution profile, or overall stability. The findings of this study suggest that the novel drug-drug solid dispersion approach is promising for enhancing the dissolution of poorly soluble drugs, when combined with soluble drugs in fixed-dose combinations.
In-vitro and in-silico investigation of anti-obesity effect of Shorea tumbuggaia
Authors:   Department of Pharmacology, Seven Hills College of Pharmacy, Tirupati - 517 561, India, Gandla Mallikarjuna
Published: November 2024

The rising prevalence of obesity has become a significant concern in both high income and low income countries. Addressing obesity has challenges due to the limitations in current treatment options. Dietary modifications have become a common approach in managing obesity and its associated risks. The study was aimed atinvestigating the anti-obesity effects of the methanol extract of Shorea tumbuggaia, focusing specifically on its ability to inhibit pancreatic lipase activity. Shorea tumbuggaia stem bark methanolic preparation was screened for total phenolic content and subjected to phytochemical tests for presence of secondary metabolites. The pancreas of a chicken was used to extract the lipase enzyme. Lipase inhibitory activity of various methanol extract concentrations was assessed using olive oil as the substrate. Additional docking investigations of Shorea tumbuggaia components were made to investigate the role in regulating obesity and its associated issues.The study revealed that the extract has exhibited concentration dependent inhibition of pancreatic lipase activity. The study findings on Shorea tumbuggaia lipase inhibitory activity are encouraging which may be due to the existence of secondary metabolites causing the inhibitory action.
ASPECTOS JURÍDICOS E CONSEQUÊNCAIS DA REPARTIÇÃO CONSTITUCIONAL DE COMPETÊNCIAS QUANTO A REGULAÇÃO DO TRANSPORTE AQUAVIÁRIO LONGITUDINAL NO AMAZONAS
Authors: De Alencar Alexandre Ferreira , Dos Santos Francisca Beatriz de Oliveira , Cunha Glauber Negreiros Tavares , Da Rocha Marcela Sena , Sanchez Pedro Gabriel Machado
Published: November 2024

This article addresses the legal and consequential aspects of the constitutional division of powers in regulating longitudinal waterway transport in Amazonas. The Federal Constitution of 1988 assigns the Union responsibility for operating waterway transport services that cross state borders or are located within border zones. However, regulating waterway transport within states and municipalities presents unique challenges, requiring effective coordination among federal entities. The study analyzes state norms and laws, with a focus on Law No. 5,604/2021 and State Decree No. 45,110/2022. It concludes that harmonizing regulations and fostering cooperation among regulatory agencies is essential for promoting safe, efficient, and integrated waterway transport, meeting the needs of the population, and contributing to the sustainable development of the Amazon region.
Yüksek Riskli Lezyonlarda Mastektomi Sonrası Otolog Meme Rekonstrüksiyonu
Authors:   İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Plastik Rekonstrüktif ve Estetik Cerrahi Ana Bilim Dalı, İstanbul, Türkiye, Ercan Alp
Published: November 2024

Yüksek riskli lezyonlara da tanımlanmış onkolojik amaçlı mastektomi sonrası onarımlara benzer prensiplerle yaklaşılır. Meme cebinin ve belli durumlarda nipple korunmasının avantajı ideale yakın onarımlara olanak sağlamasıdır. Otolog onarımlar daha komplike bir ameliyat süreci ve daha uzun bir nekahat süreci gerektirmesine karşın hastayla beraber yaşlanma, estetik üstünlük ve benzer bir doku ile onarım avantajlarına sahiptir. Bunun yanında implantla onarımın uzun vadeli dezavantajlarından kaçınmayı da sağlar. Modern meme onarımında hasta bazlı özelleştirilmiş tedaviler esas olup ana amaç hastaya estetik olarak ideale yakın bir meme eşleniği sağlamaktır. Bu nedenle hasta özellikleri göz önüne alınan ve birkaç adım ileriyi öngören bir tedavi planı yapılmalıdır. Eğer altın standart olan karın bazlı flepler (DİEP flep) kullanılamayacaksa sırt, uyluk ve bel gibi alternatif alanların flepleri de düşünülmeli ve kullanılmalıdır.
Kutanöz Damar Sistemi
Authors:   Ankara Eğitim ve Araştırma Hastanesi, Dermatoloji Ana Bilim Dalı, Ankara, Türkiye, Örenay Özge Mine , Duran Yurdanur ,   Ankara Eğitim ve Araştırma Hastanesi, Dermatoloji Ana Bilim Dalı, Ankara, Türkiye
Published: November 2024

Kutanöz kan damarlarının, cilde oksijen ve besin desteğinin sağlanması, yara iyileşmesi, immün reaksiyonlarda rol oynaması, normal doku hemostazının devamlılığı, vücut ısısının düzenlenmesi ve kan basıncı kontrolü gibi birçok farklı işlevi bulunmaktadır. Damar duvarı endotel hücreleri, perisitler ve düz kas hücrelerini içermektedir. Bu hücreler ve hücrelerden salınan sitokinler, inflamasyon ve anjiyogenezde büyük öneme sahiptirler. Kutanöz damar yapı ve fonksiyonlarının anlaşılması, birçok deri hastalığının patogenezinin anlaşılmasına katkı sağlamaktadır
Lenfödem
Authors:   SBÜ Ankara Eğitim ve Araştırma Hastanesi, Dermatoloji Ana Bilim Dalı, Ankara, Türkiye, Ünsal Gülfem
Published: November 2024

Lenfödem, vücutta lenfatik sıvının artarak toplanmasıyla karakterize bir hastalıktır. Lenfödem sınıflaması ve evrelemesi için birçok sistem önerilmiştir. Lenfödem tanısı kliniktir; ayrıntılı öykü alınmasına ve kapsamlı fizik muayeneye bağlıdır. Lenfödem tedavisi, doğru tanı, başarılı sınıflandırma ve hasta eğitiminden oluşur. Ne yazık ki, lenfödem için kesin bir tedavi yoktur ama etkili tedaviler mevcuttur. Tedavi seçenekleri ameliyatsız ve cerrahi tedaviler olmak üzere iki ana grupta toplanabilir. Hasta eğitimi hem çok önemli hem de zorunludur. Lenfödem, hastaların fonksiyonel ve psiko-sosyal yaşamları açısından ciddi sorunlar doğurabilir ve yaşam kalitesinin bozulmasına neden olabilir. Etkilenen uzuvlardaki ağırlık, ağrı, azalmış hareket açıklığı, enfeksiyon ve bozulmuş yara iyileşmesi nedeniyle işlev kaybı olabilir. Bu yüzden lenfödemin erken tanısı ve tedavisi önemlidir.
THE CONTENT OF HEAVY METALS IN HONEY AS INDICATORS OF POLLUTANTS
Authors: Kunić Selma
Published: November 2024

Honey and honeydew are natural foods with a very complex composition that contain both, organic and inorganic ingredients. Regardless of the progress of the industry, it can't be replaced by some production process.The quality of honey varies from year to year, and bees can never produce the same honey and honeydew. Weather conditions, grazing, treatment of bees, proximity to industry, roads, etc., greatly affect the quality of the obtained honey. Although minerals and heavy metals are minor constituents of honey, they play a vital role in determining its quality.The goal of the research is to assess the qualitative status of honey based on the content of contaminants, heavy metals from the area of the Tuzla Canton.The research was conducted on 30 (thirty) honey samples. The samples were collected in the period September/October 2022 and constitute the grazing of the specified year.In the samples that were the subject of research, As and Cd did not exceed the limit of quantification (LOQ = 0.009 mg/kg). Current regulations does not define MRL’s for these two metals. As for the quantified amount of lead (Pb), it was the same in 12 samples and in 11 samples there was an evident deviation from the MRL. The measured lead (Pb), values range from 0.06 to 5.34 mg/kg.The quality of bee products from the aspect of contamination with heavy metals can serve as bioindicator of environmental pollution, that is, as an indicator of the level of good beekeeping practices.
KEYWORDS:honey; honeydew; heavy metals; Tuzla canton
INFLUENCE OF MACERATION,SOLVENT TYPES,AND EXTRACTION DURATIONS ON THE YIELD OF MILK THISTLE SEEDS(SILYBUM MARIANUM)EXTRACTION
Authors: Makić Halid , Hotić Samira , Hodžić Elvisa , Stojanović Nenad , Ibrahimpašić Jasmina , Dedić Samira , Ćehajić Gradinović Emina
Published: November 2024

The study investigated the extraction yield of defatted Silybum marianum seed samples using maceration as the sole extraction technique. Different solvent types (methanol, ethanol, and water) and extraction durations were tested. Prior to extraction, the samples were ground and defatted with n-hexane. For each combinationofsolvent type, and extraction duration, the extracted mass (g of extract/g of defatted sample) was determined. The impact of each parameter on the yield was analyzed, revealing significant effects.Results showed that water-based maceration for 4 hours yielded the highest average mass of dry extract, followed by shorter durations at 2 hours. Ethanol occasionally outperformed methanol, particularly at the 2-hour mark, but methanol consistently produced lower yields across longer extraction durations. These findings emphasize the need for careful optimization of solvent type and extraction duration to maximize extraction yield.Subsequent analysis using Tukey's HSD test revealed significant differences in dry extract mass among solvents. Water yielded the highest at 2 and 4 hours, ethanol at 4 hours, and methanol at 4 hours as well.
KEYWORDS:Silybum marianum;maceration;solvent types;plant extraction,yield analysis
Determine Electronic Procurement, Top Management Support and Supply Chain Performance of Selected Coast County Governments of Kenya
Authors: Begombe Ndegwa , Mohamed Dr. Zura , Kavale Dr. Stanley
Published: November 2024

The general objective of the study was to investigate the moderating effect of top management support on electronic procurement and the performance of supply chain performance of coast counties of Kenya. The specific objectives of the study were to determine effect of e-tendering practice, e-ordering processing, e-material management practice, e-supplier management practice, e- payment practice and moderated by top management support on the performance of supply chain performance of selected coast county governments of Kenya. The study employed the transaction cost theory, technology acceptance model, material management theory and the theory of performance. The target population was 561 employees in Kwale, Kilifi, Mombasa and Tana-River counties. The Yamane sample size determination formula was used to get a sample size of 329 employees. The study found out that e-tendering practice, e-ordering practice, e-material management practice, e-supplier management practice and e- payment practice positively and significantly affect supply chain performance of coast county governments of Kenya. Moderated multiple linear regression results indicated that top management support positively and significantly moderate the relationship between e-tendering practice, e-ordering practice, e-material management practice, e-supplier management practice, e- payment practice and supply chain performance of the Coast County governments. The study concluded that e-tendering practice, e-ordering practice, e-material management practice, e-supplier management practice, e- payment and top management support positively and significantly affect performance of the coast county governments of Kenya. The study recommended that counties should implement e-tendering practice, e-ordering practice, e-material management practice, e-supplier management practice, e- payment practice and encourage top management support so as to increase their supply chain performance.
A PESQUISA NA PRÁTICA DOCENTE COMO MECANISMO PARA UMA APRENDIZAGEM SIGNIFICATIVA E EMANCIPATÓRIA NO CONTEXTO DE UMA ESCOLA DO CAMPO
Authors: Bard Junior Sergio
Published: November 2024

Este artigo busca apresentar concepções sobre o professor pesquisador, mostrando que os docentes podem propor melhorias no ensino atual por meio de suas pesquisas e práticas escolares, contribuindo assim para o desenvolvimento e avanços significativos na educação. É extremamente necessário à valorização dos aspectos da prática que está totalmente ligada com o bom desempenho do trabalho docente, portanto, esta pesquisa procurou mostrar através de uma abordagem realizada de forma qualitativa em uma instituição de ensino que é plenamente possível os professores desenvolverem pesquisas voltadas para uma reflexão da sua atuação profissional, com resultados compensadores. Este trabalho também mostra que ato de investigar deve ser uma atividade permanente na vida profissional do professor na busca constante de conhecimentos que possam transformar a realidade escolar e contribuir de forma significativa para a sua comunidade ao desenvolver projetos para melhoria do sistema educacional e principalmente da condição humana a favor de um convívio social digno, de uma aprendizagem efetiva, precisa ser agente transformador.
COMO A LOGOTERAPIA PODE ABRAÇAR OS PÓS BARIÁTRICOS: UMA ABORDAGEM TERAPÊUTICA PARA TRANSFORMAÇÃO PESSOAL
Authors: Tissen Mônica Rogalsky , Silva Diego da , Silva Jaqueline do Rossio
Published: November 2024

Este trabalho explora a aplicação da logoterapia na vida de indivíduos pós-bariátricos, focando na transformação pessoal e na adaptação ao novo estilo de vida. A justificativa reside na necessidade crescente de suporte psicológico especializado para pacientes que passam pela cirurgia bariátrica e enfrentam desafios emocionais e existenciais. O objetivo é analisar como a logoterapia pode contribuir para o processo de adaptação e sentido pessoal desses indivíduos. A pesquisa adota uma abordagem qualitativa, com revisão de literatura sobre logoterapia e estudos de caso de intervenções terapêuticas. Os resultados evidenciam que a logoterapia facilita a adaptação dos pacientes, ajudando-os a encontrar um novo sentido e a melhorar a qualidade de vida. Conclui-se que a logoterapia oferece uma abordagem valiosa para o suporte psicológico de pósbariátricos, promovendo uma transformação pessoal significativa e o enfrentamento dos desafios emocionais associados ao processo de recuperação e trabalhando para preservar-se do reganho de peso.
MICROAGULHAMENTO: ALTERNATIVA TERAPÊUTICA PARA O TRATAMENTO DA ALOPECIA ANDROGENÉTICA
Authors: Queiroz Luciane Rodrigues de , Martins Stela Alves , Lima Felipe Monteiro , Melo Danielle Alves de
Published: November 2024

Este artigo aborda o microagulhamento como alternativa terapêutica para a alopecia androgenética, uma condição de perda capilar comum entre homens e mulheres, decorrente de fatores genéticos e hormonais que deterioram os folículos capilares. O objetivo é avaliar a eficácia do microagulhamento na estimulação do crescimento capilar, observando seu impacto quando utilizado isoladamente e combinado com tratamentos tradicionais, como o minoxidil. A metodologia incluiu uma análise de estudos clínicos e revisões sistemáticas sobre o uso do microagulhamento para melhorar a consistência e espessura dos fios. Baseado na capacidade do microagulhamento de promover a produção de colágeno e liberar fatores de crescimento no couro cabeludo, o artigo destaca sua ação de revitalizar os folículos capilares e o potencial de intensificar a absorção de terapias tópicas. Os resultados demonstram que o microagulhamento, é seguro e minimamente invasivo, além de aumentar significativamente a eficácia de terapias convencionais, agregando um sentido complementar e promissor no manejo da alopecia androgenética. As considerações finais sugerem que o microagulhamento, ao ampliar as opções de tratamento, colabora para um tratamento mais eficiente e menos invasivo da queda capilar, trazendo uma melhoria significativa na busca por soluções efetivas para a regeneração capilar.
ANÁLISE DE VIABILIDADE ECONÔMICA PARA A IMPLANTAÇÃO DE SISTEMAS DE GERAÇÃO DE ENERGIA SOLAR FOTOVOLTAICA E EÓLICA PARA O ABASTECIMENTO DO MUNICÍPIO DE JANAÚBA - MG E REGIÃO
Authors: De Azevedo Silva Lucas , Fernando Dias Breda Jáder , Edson de Souza Fidel , Oliveira Fernandes Júlia , Silva Rodrigues Jordane , Júnio Alves dos Santos Marcos , Rocha Sudré Cleiton
Published: November 2024

Com o passar dos anos, o fator ambiental tem se tornado primordial, e com isso, aumentou-se o foco na implantação de fontes de geração de energia elétrica advindas de energias renováveis e limpas. No Brasil, a maior parte da matriz energética ainda é composta por fontes não renováveis de energia, mas isso tem mudado cada vez mais, principalmente, devido aos incentivos governamentais através de programas de crédito. De modo específico, em Minas Gerais, a matriz elétrica é fortemente ainda dependente de hidrelétricas, mas isso também vem sendo alterado, devido aos grandes potenciais energéticos advindos de outras fontes, como o vento e o sol, que são consideradas fontes renováveis de energia. A região de Janaúba, localizada no norte de Minas Gerais, como demonstrado em vários levantamentos, apresenta um grande potencial energético eólico e solar para geração de energia, entretanto ainda não há informações relevantes sobre a viabilidade econômica da implantação dessas duas fontes. Neste sentido, o presente trabalho buscou analisar esta problemática, trazendo informações relevantes através de simulações feitas no software System Advisor Model (SAM), o qual apresenta diversos mecanismos de análise de viabilidade, incluindo o Levelized Cost of Energy (LCOE) ou custo nivelado de energia, que fornece dados como o custo de energia por kWh, trazendo a possibilidade de comparação econômica entre a implantação de ambas as fontes, com o objetivo de abastecer o município de Janaúba e região. A partir das simulações feitas no SAM, foi possível concluir que existe viabilidade econômica para implantação das duas fontes, e em comparação de um sistema com outro, verificou-se uma diferença de 1,66%, favorável ao sistema de geração de energia eólica em termos de LCOE, de modo a se mostrar mais viável, devido a possuir um maior fator de capacidade produtiva no intervalo considerado de 20 anos.
Contextual Fear Conditioning Uncovers Spine and Learning Deficits in the Retrosplenial Cortex in a Familial Alzheimer’s Disease Mouse Model
Authors: Rao Aliana
Published: November 2024

While excitatory synapse loss is documented in the brains of Alzheimer’s Disease (AD) patients, its role in episodic learning decline, one of the first evident AD symptoms, is unclear. The retrosplenial cortex (RSC), a cortical structure required for episodic learning, provides an ideal entry point to study the role of synapse loss in cognitive decline in AD since it is a site of high amyloid load and dysfunctional early in AD progression. Further, excitatory synapse assembly, both turnover and clustered synapse formation, is highly correlated with episodic learning performance in the RSC. We hypothesize alterations in synapse assembly in the RSC of AD patients contribute to early cognitive decline in the disease. To address this hypothesis, we examined both excitatory synapse density in the RSC and contextual learning in a familial AD (fAD) mouse model, an early onset amyloid model of AD. Importantly, we find age-dependent excitatory synapse loss in the RSC of fAD mice, as measured by imaging and quantification of GFP-labeled dendritic spines. Further, prior to frank spine loss in 5-month-old fAD mice we found episodic learning deficits, as measured by contextual fear conditioning (CFC). Using this early time point, we examined spine dynamics in vivo with MP imaging in the RSC of fAD mice or controls while engaged in CFC learning. Interestingly, we find deficits both in spine turnover and clustered spine formation and a loss of correlations of these spine metrics with CFC performance, suggesting aberrant spine dynamics may be causal in episodic learning deficits in this AD model, consistent with our hypothesis. Future studies will pharmacologically target these aberrant spine dynamics in fAD mice in an effort to strengthen the causal link between alterations in synapse assembly and cognitive decline in AD as well as provide potential therapeutic approaches to reverse early stages of the disease.
Rehabilitation Potential Among Institutionalised Homeless Persons with Mental Illness during COVID-19: A Cross-Sectional Study
Authors: Sinu Jesin Timothy  , Ezhumalai Sinu , Ragesh G.
Published: November 2024

Aim: To assess the rehabilitation potential and social well-being among homeless persons with mental illness.
Methods: The study utilised quantitative methodology to assess rehabilitation potential and social well-being. It was conducted at Udayam Shelter Home, Kozhikode, Kerala. The district administration initiated the Udayam Project in Kozhikode to rehabilitate destitute individuals rescued from the streets during the Corona Virus Disease 2019 (COVID-19) outbreak in March 2020 and to provide shelter across various camps in the district. The researcher prepared a rehabilitation potential checklist, validated by experts, and a standardised scale was used to assess social well-being. Descriptive statistics were used for quantitative data analysis. Ethical clearance was obtained from the NIMHANS Institute's ethics committee.
Results: Over one-third (40%) of the participants were older adults aged above 60 years. All the participants in the study were male. The homeless women identified as needing care and protection were shifted to other centres due to the lack of facilities at the Udayam shelter care home. Previous occupational status revealed that before coming to the rehabilitation centre, most respondents were employed as unskilled labourers. They included daily wagers, lottery sellers, and helpers in hotels and restaurants. Others were skilled labourers, including masons, carpenters, and electricians. Most respondents were from urban and semi-urban areas. Homeless persons with mental illness (HPMI) with mood disorders exhibited better social well-being compared to those with other diagnoses. HPMI diagnosed with psychosis were reported to have very little social actualisation compared to others.
WAYS TO COMPLETE TASKS TO INCREASE THE FUNCTIONAL LITERACY OF STUDENTS IN THE CHAPTER “PRESSURE” FROM PHYSICS
Authors:   Joint Institute for Nuclear Research, Dubna, Moscow Region, Russia, Azhibekov A.Q.
Published: November 2024

Бұл мақалада физикадан қысым ұғымын қалыптастырудағы оқушылардың функционалдық сауаттылығын арттыруға арналған тапсырмаларды орындау әдістемесі қарастырылады. Қазіргі білім беруде мектеп оқушыларының функционалдық сауаттылық деңгейін арттыру мәселесі өзекті болып табылады және тиімді әдістемелік тәсілдерді қажет етеді. Мақалада қысымның практикалық қолданысын талдау, олардың басқа физикалық шамалар мен құбылыстармен байланысы, сондай-ақ есептерді шешу дағдыларына үйрету кіретін тапсырмаларды орындаудың жүйелі тәсілі ұсынылады. Берілген әдістемелер мен тапсырмалар теориялық оқыту, зертханалық тәжірибелер мен практикалық тапсырмаларды біріктіруге негізделген, бұл материалды тереңірек меңгеруге және оқушылардың аналитикалық әрі логикалық ойлау қабілеттерін, сыни ойлау дағдыларын, теориялық білімдерін практикалық тұрғыда, сонымен бірге өмірлік қажеттіліктерге пайдалана алу дағдыларын қабілеттерін дамытуға ықпал етеді. Нәтижесінде, ұсынылған әдістемелік материалдар оқушылардың физика пәніне деген қызығушылығын арттырып, физика пәнінен функционалдық сауаттылықтарын дамытуға ықпал етеді.Ұсынылып отырған әдіс жоғары оқу орындары мен мектептердің физика мұғалімдеріне осы тақырып бойынша оқытуды ұйымдастыру кезінде, сондай-ақ физика саласындағы білімдері мен дағдыларын жетілдіруге және функционалдық сауаттылық деңгейін арттыруға ұмтылатын оқушыларға пайдалы болуы мүмкін.