bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and structure of inflammatory periodontal diseases in tuberculosis in school-age children
Authors: Smolyar N.I. , Shylo M.M.
Published: September 2022

Objective — to study the prevalence and structure of inflammatory periodontal diseases in respiratory tuberculosis patients and infected with mycobacterium tuberculosis (MTB) school-aged children.

Materials and methods. The examination was carried out in 168 (100 %) patients with respiratory tuberculosis and MBT-infected children and adolescents of school age (from 6 to 17 years) with inflammatory diseases of periodontal tissues. Among the examined schoolchildren, 102 (60.72 %) were school-aged children with respiratory tuberculosis (the first group). The second group included 66 (39.28 %) infected MTB schoolchildren. The control group consisted of 45 practically healthy school-age children. The conducted examination of the dental status included the study of the prevalence of periodontal pathology, the intensity of the lesion and the severity of its course in different age groups of school children.

Results and discussion. It was established that the prevalence of periodontal tissue disease in school-aged children with tuberculosis ((87.25 ± 2.36) %) and MTB-infected ((65.15 ± 2.15) %) exceeded that of healthy children ((24.45 ± 2.12) %) by 4.0 and 3.7 times, respectively. The most common pathology was an inflammatory lesion of the gums in the form of catarrhal gingivitis, which was almost 4 times higher than such data in children of the control group. The course of catarrhal gingivitis was diagnosed in the form of acute, chronic and exacerbation of the chronic process. At the same time as the prevalence of catarrhal gingivitis increased with age, the frequency of periodontitis increased in the children of the examined groups, the prevalence of which was most pronounced among patients with tuberculosis, much less among those infected with MTB. The assessment of the intensity of periodontal tissue damage using the PMA index revealed its increase with age, most pronounced among patients with tuberculosis, somewhat less among those infected with MTB.

Conclusions. The prevalence of inflammatory diseases of periodontal tissues in patients with respiratory tuberculosis and MTB-infected children increases with age and is manifested by gum damage in the form of both catarrhal gingivitis and periodontitis, the highest prevalence of this pathology was observed among 15—17-year-old schoolchildren with pulmonary tuberculosis, less is expressed in infected MTB.
Thyroid tuberculosis: rare location or rarely diagnosed? Literature review
Authors: Matvyeyeva S.L. , Shevchenko O.S.
Published: September 2022

Objective — to study of the frequency, clinical picture, diagnosis and treatment of tuberculosis of thyroid gland.

Materials and methods. Analyses the date of the world experience and own observations.

Results and discussion. Thyroid tuberculosis is a less frequent localization of this disease. Currently, most authors believe that thyroid tuberculosis is diagnosed in 0.1–1 % of all known cases of tuberculosis. Clinical observations have found that the thyroid gland is more often involved in the tuberculous process with a generalized miliary process, and, as previously thought, in this case there are no clinical signs of damage to the thyroid gland. A variable clinical presentation of thyroid tuberculosis was demonstrated. It is usually presented with local symptoms associated with diffuse enlargement of the thyroid gland. It is difficult to estimate the quantity of diagnosed cases due to insufficient knowledge of the doctors about this pathology and difficulties of tuberculosis etiology diagnosis. Tuberculous etiology must be ruled out in all lesions on the median surface of the neck. Fine-needle biopsy can help to confirm the diagnosis of thyroid tuberculosis, but the final diagnosis is possible only with histological or cytological studies. The diagnosis of thyroid tuberculo­sis requires the use of most of all the methods used in the diagnosis of tuberculosis: from the simplest (such as X-ray or Mantoux test (with 2 international units of tuberculin) methods to modern rapid molecule-genetic tests XpertMTB/Rif that detect specific fragments of MTB DNA in serum or plasma). Ultrasound and computer tomography also help the clearing of the diagnosis. Surgical treatment in combination with antimycobacterial chemotherapy is effective.

Conclusions. Further investigations are needed to understand the definition, diagnosis and treatment of tuberculosis among other diseases of thyroid.
Impact of delayed initiation of antiretroviral therapy in patients with HIV infection
Authors: Shevelova O.V. , Shostakovich­–Koretska L.R. , Lytvyn K.Yu. , Kushnierova O.A.
Published: September 2022

Objective — to analyze the effect of the duration of the period from the moment of infection to the appointment of antiretroviral treatment in patients with HIV infection as a predictor of an unfavorable course of the disease.

Materials and methods. A retrospective and prospective study was conducted among a cohort of people living with HIV (PLHIV), which included 450 patients. The observation lasted 60 months. 63 patients died from HIV-related causes, 14 from non-HIV and immune reconstitution inflammatory syndrome (IRIS) causes, 69 patients interrupted antiretroviral therapy (ART) for various reasons during the follow-up period. By the end of the follow-up period, 304 patients remained on ART. Statistical processing of the results was carried out using the STATISTICA v. 6.1 application package.

Results and discussion. Based on the results of a correlation analysis of clinical and laboratory parameters of a cohort of HIV-infected patients, 10 main risk factors were selected, including the delayed initiation of antiretroviral treatment. After 5 years of follow-up, the main reason for the loss of patients from the cohort was interruption of therapy — 69 (15.3 %) people, 63 (14.0 %) died from HIV-related causes, and 14 (3.1 %) died from causes unrelated to HIV and IRIS. Causes associated with the undesirable clinical outcomes of ART were noted in 30.4 % of people — allergic reactions, taking therapy together with anti-TB therapy, in turn, led to the development of IRIS and an increase in adverse events.

Conclusions. The analysis shows that despite the high intensity of the prescribed primary treatment regimens for patients with HIV infection, such a factor as the delayed initiation of ART has a significant negative impact on the further course of HIV infection and the development of adverse events, worsening the prognosis of the disease.
The Impact of Instagram Social Media and e-Mouth of words as a Marketing Strategy on Purchasing Decisions
Authors: Prastiwi Estik Hari
Published: September 2022

Study this aim to prove and analyze the influence of social media Instagram and mouth of word on decision purchase by direct or through brand equity mediation. Method data collection used is with method  questionnaire, sample study of 150 respondents. The method sample used namely purposive sampling, namely respondents who have buy fashion products in e-commerce at least twice. Method data analysis used WarpPls 7.0 . Research results show Instagram influential significant to decision purchase , word of mouth is influential significant to decision purchase. Brand equity is as mediation of Instagram's influence on decision purchases. Brand equity is also a mediation the influence of mouth of word on decision purchase
ENTREPRENEUR PASSION, SKILL AWARENESS ON ENTREPRENEUR SELF EFFICACY AND ENTREPRENEUR INTENTION
Authors: Karya Denis Fidita , Mardhotillah Rachma Rizqina , Lukiyono Yauwan Tobing , Putri Endah Budi Permana
Published: September 2022

This study investigates the role of entrepreneurial passion, self-skill awareness, and entrepreneurial self-efficacy on entrepreneurial intention. This study uses a quantitative method with a purposive sampling approach. The sample used in this study is the Surabaya community which does not yet have a business. The results showed that entrepreneurial passion had a significant positive effect on entrepreneurial self-efficacy, self-skill awareness had a significant positive effect on entrepreneurial self-efficacy, and entrepreneurial self-efficacy had an influence on entrepreneurial intention.
SIGNALLING THEORY STUDY: PREDICT FUTURE CASH FLOWS WITH EARNINGS AND CASHFLOWS IN CONSUMER GOODS INDUSTRIES BEFORE PANDEMIC ERA
Authors: Khasanah Uswatun , Samsi Nur , Choiri Choiri , Zainab Zainab
Published: September 2022

This study aims to determine which of the cash flows and earnings have a better ability to predict future cash flows in the two years after the study period. This research was conducted on consumer goods industries listed on the Indonesia Stock Stock Trade in 2016 – 2019 employing a purposive examining procedure. (Dechow, Kothari, & Watts, 1997) found that earnings have a better ability to predict future cash flows than operating cash flows themselves. Another study conducted by (Dahler & febrianto, 2007) utilizing numerous straight relapse models found that operating cash streams for the current year have a better ability than profit in anticipating future working cash streams for both bunches of companies that have positive and negative benefits. Utilizing the same model, this study concludes that earnings have a better ability to predict future cash flows than cash flows themselves. However, cash flows still have a significant ability to predict future cash flows. In expansion, this consider too succeeded in demonstrating that profit has an incremental capacity to anticipate future cash streams.
REBOUND MODEL TO TOWARD REGIONAL ECONOMIC RESURRECTION POST COVID-19 PANDEMIC IN BANYUWANGI REGENCY
Authors: Suprihatin Endang , Hamid Abdul
Published: September 2022

Banyuwangi Regency which is located in the eastern sunrise of Java seeks synergistically to restore the economy after the Covid-19 pandemic, namely by echoing the Banyuwangi Rebound program which contains three main program  for the era of  revival,  First, the pandemic handling ecosystem consists of various steps to deal with Covid-19 and improve the level of health of citizens in general, in addition to handling pandemics such as us towards one hundred percent of childhood vaccination, various preventive, promotive, curative, and rehabilitative measures we integrate. Including towards zero stunting, village midwife support, people's nutritional supplements, spurring sports activities, and revitalization of school health units, the next ecosystem is economic recovery. Starting from MSME development programs, agriculture, infrastructure, rural development, to tourism. They are designed to create jobs and restore the economic movement of citizens. The third ecosystem is harmony strengthens social solidarity, develops human resources in terms of education, maintains environmental sustainability, to strengthen harmony between religious people. Banyuwangi Rebound is a comprehensive movement reaching all sectors and stakeholders to bring Banyuwangi able to Rebound amoung various challenges. Economic growth is starting to return positively. The wheels of the economy began to move, one of the indicators is financing from banks to MSME that are soaring. Banyuwangi's banking credit growth is far above the national average. In addition, the culture of innovation developed by the government continues to develop, in the midst of this pandemic, the poverty rate rose even though Banyuwangi experienced the lowest increase in East Java 0.1%.
Una aproximación etnobotánica a la comercialización informal de Cactáceas nativas en las rutas nacionales 9 y 34 en la provincia de Santiago del Estero, Argentina.
Authors: Demaio Pablo , Trillo Cecilia
Published: September 2022

Introducción y objetivos: La provincia de Santiago del Estero está atravesada por las Rutas Nacionales N° 9 y 34, en sus banquinas se instalan puestos de venta informales de Cactáceas. Con los objetivos de registrar e identificar la diversidad de especies comercializadas, considerar si sufren algún grado de amenaza según la UICN, describir las formas de acceso a las mismas en los ambientes de extracción y caracterizar los espacios informales de comercialización, se abordó desde una perspectiva etnobotánica el estudio de esta actividad.
M&M: Se realizaron entrevistas abiertas a pobladores de ambos sexos entre 20 y 60 años, en 25 puestos sobre la RN9 y 14 puestos sobre la RN34. En cada puesto se registró cantidad de especies, nombres locales, usos y forma y lugar de recolección, considerando puesto estable al que tenía al menos 10 ejemplares de Cactaceae en venta.
Resultados & Conclusiones: Se comercializan 19 taxones, 13 silvestres y 6 cultivados, todos categorizados “Preocupación menor” (LC) por IUCN. La técnica de recolección consiste en la búsqueda de ejemplares en los alrededores de las viviendas. Los puestos son atendidos en su mayoría por mujeres de entre 20 y 50 años y niños de entre 10 y 15 años. Los vendedores de cactus poseen un Sistema de Conocimiento Local (SCL) que les permite utilizar de manera flexible plantas disponibles en su entorno inmediato, a las que les adjudican un nuevo valor. Considerando la categoría de IUCN de todas las especies comercializadas, la actividad no pondría en riesgo la diversidad. Este comercio podría representar una actividad económica sustentable para pobladores de zonas áridas.
Pregnancy in the Era of the Environmental Crisis: Plastic and Pollution
Authors: Ragusa Antonio , Principi Giulia , Matta Maria
Published: September 2022

Objective: The environmental crisis we are experiencing is becoming a more popular topic of expert discussion and analysis. Human activity and expansion on the planet are exacerbating climate change and global warming, this, together with the increase in plastic production, and general pollution, posing a threat to our resources, supplies, and survival. This research aims to review what is known about the association between pollution and pregnancy and sensitize experts to women’s education towards healthier behaviors. Mechanism: We chose to focus on the effects of the environment on fetal development and maternal health, considering various studies that highlight the potential consequences of exposure to certain environmental stressors. The paper briefly illustrates the probable mechanisms that, starting from cellular and intracellular damage, determined above all by plastics, lead to chronic activation of the immune system in response to danger and, therefore, to epigenetic modifications at the base of diseases in adulthood. Findings in Brief: We describe the effects of the main pollutants on pregnancy, with particular attention to the role of plastic. Finally, we briefly outline some individual possible solutions to this complex problem. Conclusions: In the era of environmental crisis, becoming aware of the mechanisms behind biological damage resulting from exposure to certain pollutants and plastics, especially in a period as sensitive as pregnancy, should be the driving force behind a change of direction. As physicians, this means educating our patients and recommending individual solutions to reduce the impact of contaminants to provide the best possible environment for women’s and children’s health, especially during the delicate period of pregnancy; but the ultimate solution is to drastically reduce global plastic production and pollution, and to recycle the plastic that is needed anyway.
Is it Good to be Born as a Late Preterm Infant?
Authors: Raguž Marjana Jerković , Šoljić Katarina , Prce Željka , Mikulić Vinka , Barišić Tatjana , Grgić Svjetlana
Published: September 2022

Background: This study conducted at the Clinic for Children’s Diseases of the University Clinical Hospital Mostar, aims to highlight the characteristics, frequency, course, most common complications and treatment outcomes of pregnant women and their late preterm infants according to gestational age. Methods: This study is a retrospective epidemiologic study for the period from 1/1/2018 to 31/12/2021. The study included all the preterm infants who were born at a gestational age from 34+0/7 to 36+6/7 weeks and their mothers. Results: In the period under study, a total of 7178 infants were born, of which 253 (3.52%) were late preterm infants. The results show that most mothers were between 30 and 39 years of age, pregnant for the first time with a single pregnancy, delivered by caesarean section, with complications in 53.1% of the pregnancies. All the analyzed pathological conditions were more common in the pregnancies which ended at 34 weeks. Our results indicate that the late preterm babies had a good birth weight (53.8%) and high vitality scores (93%) at birth, but these scores were not confirmed on the first day of life. A significant number of late preterm infants had some pathological condition which was treated in the intensive care units (ICU) (p < 0.001). Conclusions: The study concludes that half of the pregnant women had risk factors which were the basis for the preterm births and the development of complications in the late preterm infants. Furthermore, despite good birth weight and vitality scores at birth, only one fifth of the late preterm infants were not treated with medications or developed pathological conditions, whereas only one third required no intensive care treatment. It is, therefore, necessary to improve the monitoring and understanding of such pregnancies, implement antenatal corticosteroid therapy, and increase parental awareness to ensure long-term and frequent monitoring of late preterm infants by pediatricians.
Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease
Authors: Török Nóra , Maszlag-Török Rita , Molnár Kinga , Szolnoki Zoltán , Somogyvári Ferenc , Boda Krisztina , Tanaka Masaru , Klivényi Péter , Vécsei László
Published: September 2022

Background: Earlier studies reported alterations of the kynurenine (KYN) pathway of tryptophan (TRP) metabolism in Parkinson’s disease (PD). The first rate-limiting enzymes indoleamine 2,3-dioxygenase (IDO) and tryptophan dioxygenase were observed upregulated, resulting elevated KYN/TRP ratios in the serum and cerebrospinal fluid samples of patients with PD. More and more single nucleotide polymorphisms (SNPs) have been identified in a population of PD. However, little is known about the impact of genetic variations of the IDO on the pathogenesis of PD. Methods: SNP analysis of IDO1 was performed by allelic discrimination assay with fluorescently labelled TaqMan probes and a subgroup analysis was conducted according to the age of PD onset. The frame shifts variant rs34155785, intronic variant rs7820268, and promotor region variant rs9657182 SNPs of 105 PD patients without comorbidity were analyzed and compared to 129 healthy controls. Results: No significant correlation was found in three SNPs between PD patients and healthy controls. However, the subgroup analysis revealed that A alleles of rs7820268 SNP or rs9657182 SNP carriers contribute to later onset of PD than non-carriers. Conclusions: The study suggested that SNPs of IDO1 influenced the age onset of PD and genotyping of SNPs in certain alleles potentially serves as a risk biomarker of PD.
Evaluation of Efficacy of Oil Adjuvanted H5N6 Inactivated Vaccine against Highly Pathogenic H5N6 and H5N1 Influenza Viruses Infected Chickens
Authors: Kuruppuarachchi Kuruppu Arachchillage Praboda Priyangi , Jang Yunyueng , Seo Sang Heui
Published: September 2022

Background: Over the last 20 years, circulating highly pathogenic (HP) Asian H5 subtype avian influenza viruses have caused global pandemics in poultry and sporadic infections in humans. Vaccines are a desirable solution to prevent viral infections in poultry and reduce transmission to humans. Herein, we investigated the efficacy of an oil-adjuvanted inactivated H5N6 vaccine against highly pathogenic H5N6 and H5N1 influenza virus infections in chickens. Methods: The polybasic amino acid cleavage site depleted HA gene and NA gene of A/Waterfowl/Korea/S57/2016 (clade 2.3.4.4) (H5N6) was assembled with the rest of the A/PR/8/34 (H1N1) genes to construct the vaccine virus. The vaccine virus was propagated in fertilized eggs, partially purified using a tangential flow filtration (TFF) system, and inactivated using formalin. The chickens were intramuscularly immunized with 384 HA, 192HA, and 96HA units of oil-adjuvanted inactivated H5N6 vaccine. Antibody titer, survival rate, and lung pathology were evaluated against the homologous H5N6: A/waterfowl/Korea/S57/2016 (clade 2.3.4.4) and heterologous H5N1: A/Hong Kong/213/2003 (clade 1) viruses 12 and 4 weeks post-vaccination (p.v.), respectively. Data were statistically analyzed using the Mann-Whitney U test. Results: The 384HA (n = 10) and 192HA (n = 5) antigen-immunized chickens showed 100% survival after lethal infections with homologous H5N6, and no virus shedding was observed from tracheal and cloacal routes. All chickens that received the 384HA vaccine survived the challenge of heterologous H5N1 after 4 weeks of immunization. The chickens that received the 384HA vaccine showed mean HI titers of 60 and 240 after 12 and 4 weeks of vaccination, respectively, against HP H5N6, whereas a mean HI titer of 80 was observed in sera collected 4 weeks after vaccination against HP H5N1. Conclusions: Our findings indicate that one dose of 384HA oil-adjuvanted inactivated H5N6 vaccine can induce a long-lasting immune response against both homologous H5N6 and heterologous H5N1 infections in chickens.
Protective Effects of Shi-Zhen-An-Shen Decoction on the Cognitive Impairment in MK801-Induced Schizophrenia Model
Authors: Liu Xinyao , Feng Sitong , Feng Zhengtian , Ma Chao , He Yi , Li Xue , Ning Yanzhe , Sun Zuoli , Jia Hongxiao
Published: September 2022

Background: Cognitive dysfunction is a core feature of schizophrenia that strongly correlates to the patients’ difficulties in independent living and occupational functioning. Synaptic dysfunction may result in cognitive and behavioral changes similar to what have been identified in schizophrenia. Shi-Zhen-An-Shen Decoction (SZASD) is the empirical formula of traditional Chinese medicine adopted in treating psychiatric symptoms, especially the cognitive impairment in schizophrenia patients, with proven efficacy in the long term of clinical practice in Beijing Anding Hospital, Capital Medical University. However, the mechanisms of SZASD on the cognitive improvement in schizophrenia is still unclear. Here, we aim to investigate the underlying mechanisms of the impact of SZASD on the cognitive impairment in MK801-induced schizophrenia-like rats. Methods: Six rat groups (n = 12 per group) were subjected to different treatments for 14 days. All the six groups were injected intraperitoneally with a given volume of 0.9% saline and MK801 (0.2 mg/kg) for consecutive 14 days for modelling. And the rats in the SZASD-treated groups and the clozapine-treated group were given SZASD (low, middle, and high doses) or clozapine, respectively, by intragastric administration. Then, we performed behavioral tests after the treatments, and the rats were sacrificed on the 19th day for biological analysis. Results: Behavioral tests indicated that SZASD mitigated the aberrant motor activity and improved schizophrenia-like rats’ spatial reference memory and sensory gating ability. Furthermore, SZASD significantly increased the expressions of PSD95, BDNF, and synapsin I in the hippocampus of MK801-induced schizophrenia-like rats. Conclusions: Our findings suggest that SZASD may ameliorate cognitive impairment by restoring the levels of synaptic proteins in the hippocampus.
A Phenomenological Study on the Lived Experiences of Self-Aware-Non-Fluent English Teachers
Authors: Rino Ushas Richel R. , Cortezano Glen P. , Yazon Alberto D. , Manaig Karen A. , Tesoro John Frederick B.
Published: September 2022

This study delved into the lived experiences of self-aware-non-fluent English teachers in their instructional delivery to come up with practical strategies and ways to strengthen the delivery of instruction in using the English language. Accordingly, qualitative research design and hermeneutic phenomenological processes were utilized. In analyzing the acquired responses from the participants, the following steps were applied: (1) hermeneutic phenomenological reduction; (2) imaginative variation, where the possible meanings of horizons were attained through the individual and composite structural descriptions; lastly, (3) essence, where the synthesis and reflections were made to form implications. The epoche was also applied before and during the conduct of this qualitative research to suspend the researcher’s connection to the experiences of the participants and maintain bias-free data.  Based on the testimonies gathered from the participants, 139 subordinate themes, 28 superordinate themes, and four (4) main themes were unveiled. Challenges encountered in using the English language in an English classroom, Practices in developing English language fluency in the classroom, Various training on enriching the English language fluency among English teachers; and Favorable experiences as English teachers were the four (4) main themes which highlighted all the significant occurrences in the classroom regarding English language fluency. As a result, a booklet entitled “I am a Pedagogue: Repertoire of English Fluency Enrichment Strategies” was crafted which emphasized strategies acquired from the lived experience of the participants and was intended to be applied by all the English teachers in Calamba City.

 

Keywords – English teachers, enrichment strategies, instructional delivery, non-fluency
Teaching Activities in An EFL Class for Refugees at Immigration Detention Center In Balikpapan-Indonesia
Authors: Tobing Rorenta
Published: September 2022

This research was designed to study teaching activities for speaking in an EFL refugee class at Immigration Detention Center in Balikpapan. The purpose of this study was to investigate the speaking activities that the teacher conducted, as well as how the teacher worked those activities and the challenges that appeared when the teacher performed teaching activities for teaching speaking. The research was done in Immigration Detention Centre, Lamaru, Balikpapan, in December 2019. The research sample in this study was one teacher of an EFL class of refugees in IDC Balikpapan. The study was based on qualitative case study research. Data were collected by using two instruments, classroom observation, and interview. The result indicated that various activities were conducted by the English teacher for teaching speaking in this class. It showed that the teacher taught ten exercises: discussion, roleplay, brainstorming, storytelling, interview, picture describing, game, presentation, field trip, and cooking activity. The teacher used the real-life situation as the topics for speaking activities in EFL class, applied pair or group learning, motivated the learners, used students centered method to encourage learners to be free to talk, and made only principal corrections when the learners were doing speaking activities. The challenges that the teacher faced while applying speaking activities in this EFL class learning process include language barriers, different educational backgrounds and life experiences, the psychological condition of the learners, and uncomfortable classroom situations. A professional teacher's certificate and training must be needed for teaching EFL refugee classes. So, it is necessary to create a particular course or class for learning to teach EFL classes for refugees in the English Education programs. EFL teacher of refugees is not only teaching language. The teacher is a facilitator, a guide, and a motivator to the EFL learners.
Estimation of Repeatability and Most Probable Producing Ability (MPPA) of Sapudi Sheep Based on Daily Body Weight Gain of Lambs from Birth to Pre-weaning and Weaning
Authors: Mudawamah Mudawamah , Anwar M. Z. , Sumartono Sumartono
Published: September 2022

This research aimed to estimate the repeatability and MPPA values of Sapudi ewes based on the lamb’s daily gain from birth to pre-weaning and weaning. Using recorded data in a pedigree of lamb, 53 data with half-sib relationship came from 14 ewes which included the record of body weight gain of Sapudi lambs from birth to pre-weaning and weaning. The data were analyzed by descriptive method with a quantitative approach. The study showed that the average daily gain of pre-weaning and weaning was 007 kg/day. The repeatability value of pre-weaning and weaning daily gain was 0.636 in the high category and 0.377 in the medium category. The MPPA daily gain values for pre-weaning and weaning ranged from -0.032 to 0.018 and -0.016 to 0.009. The research concluded that the Sapudi sheep ewes based on the MPPA daily gain pre-weaning were six heads with four rankings, while the daily weight gain weaning was ten heads with ranking of five. The highest rank of Sapudi ewes in pre-weaning and weaning daily gain was ear tag 094 with MPPA values of 0.018 and 0.009. It is recommended that further research can be conducted to estimate the repeatability value of quantitative periodically as the basis for the selection and culling of livestock.
Virtual Feedback for Compliance to Prescribed Exercise: A Randomized Crossover Trial
Authors: Visentin Denis , O'Brien Jane , Freeman Carlie , D'Orazio Alexandra , Barker Kate , Williams Andrew D.
Published: September 2022

Background

To investigate the effect of a virtual feedback environment on compliance to prescribed session exercise load and to understand the user experience related to exercise participation.

Methods

Adult clients referred to an exercise physiology clinic wore a heart rate monitor while performing prescribed exercise twice per week over 2 intervention blocks of 2 weeks each. Participants undertook aerobic exercise both with and without a virtual feedback environment in random order. Compliance to prescribed exercise was assessed as heart rate relative to prescribed levels both within and across sessions. Participants reported average pain and rating of perceived exertion for the session and completed the PACES-8 enjoyment of exercise questionnaire at session completion. Treatment effects were assessed longitudinally using mixed-effects linear regression. At study completion, 2 focus groups (n = 12) were conducted and reported using thematic analysis.

Results

Participants (n = 14) demonstrated higher mean compliance to prescribed exercise under the treatment (101 ± 10%) compared to control (50 ± 10%) condition (MD = 51%; 95% CI: 21–80; P = 0.001). Similar scores were observed under both the treatment and control conditions for rating of perceived exertion (12.3 vs. 12.2: P = 0.86), pain (2.37 vs. 0.85: P = 0.29), and enjoyment of exercise (41.2 vs. 38.6: P = 0.49). Focus groups identified themes related to biofeedback, interactivity and engagement, goal setting, and the visual environment.

Conclusion

Immersive feedback technologies can be effective to assist individuals with chronic clinical conditions to perform aerobic exercise within prescribed intensity ranges. Wide acceptability requires linking the exercise modality to the immersive environment and developing clear and meaningful goals.
Rasionalitas Dalam Ekonomi Islam
Authors: Irwan Arfin Muh. , Ma'rifa
Published: September 2022

Ratio (latin) berarti akal budi atau pikiran sehat. Rasion (ration) mengandung makna di antaranya to supply with the rations (menawarkan dengan ketentuan), to limit or to restrict the use of (membatasi penggunaan barang tertentu). Ration dalam bidang ekonomi mengerucut pada makna adanya batasan yang ditentukan oleh sebuah ketentuan. Rasional (rational) adalah lawan dari irrational, secara bahasa diartikan seperti ungkapan rational human beings (manusia yang dapat berpikir), rational behaviour (perilaku yang masuk akal)
A Study on Scale Adaptation to Determine Classroom Learning Environment Perceptions
Authors: Akkaya Gamze , Ertekin Pelin , Köksal Mustafa Serdar
Published: September 2022

This study aimed to perform a scale adaptation to determine students' perceptions of a classroom learning environment. The sample of the study consisted of 337 students for exploratory factor analysis and 1,639 students for confirmatory factor analysis. The scale known as My Class Activity adapted in this study was developed by Gentry and Gable (2001). The adapted scale is a five-point Likert-type scale consisting of four factors (interest, choice, challenge, and enjoyment). The scale was previously adapted to Turkish culture by Deniz and Saranli (2017), and in this study, we readapted the scale to Turkish culture. Exploratory factor analysis and reliability analysis of the data obtained from the scales were completed with SPSS software and confirmatory factor analysis with AMOS. As a result of the analyses of the adapted scale, it was decided to remove the challenge dimension. After the validity and reliability studies obtained from the three-factor (interest, choice, enjoyment) structure of the scale, it was concluded that the scale could be used in Turkish culture.
Differential expression of SLC33A1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of SLC33A1, encoding solute carrier family 33 member 1, in the primary motor neurons of patients with ALS. SLC33A1 was also differentially expressed in the skeletal muscle of patients with ALS. SLC33A1 transcript was present at significantly higher levels in ALS patient motor neurons as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of RTF1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of RTF1, encoding RTF1 homolog, Paf1/RNA polymerase II complex component, in the motor neurons of patients with ALS. RTF1 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. RTF1 transcript was present at higher levels in ALS patient motor neurons as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
Working with a young people’s advisory panel to conduct educational research: Young people’s perspectives and researcher reflections
Authors: Webber Charlotte , Panel Young People's Advisory , Wilkinson Katherine , Duncan Lynne G. , McGeown Sarah Patricia
Published: September 2022

Participatory research with young people centres their knowledge and experiences to generate research outcomes which are meaningful to them. In recent years, there has been an increase in participatory research within education, yet there is still little methodological insight into this approach. In this project, which explored adolescents’ reading motivation and engagement, a young people’s advisory panel was convened to ensure the perspectives and experiences of young people were central to the research. The panel consisted of 6 young people (13 – 15-years-old) from 3 schools in Scotland. The panel worked with researchers at the Universities of XX and XX and a national literacy organisation across one academic year to plan and design the project, carry out data collection and interpret the findings. To achieve this, online group meetings, an online interview training workshop, online 1-1 interviews with the first author and in person peer-interviews were conducted. In this article, the methodological practice of working with a young people’s advisory panel to carry out a research project is evaluated using thematic analysis of panel members’ reflections and meeting content. A discussion of the benefits, limitations, and practicalities are provided for researchers interested in working closely and collaboratively with young people to conduct educational research.
Differential expression of LOC100129198 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of LOC100129198 in primary motor neurons of patients with ALS. LOC100129198 was also differentially expressed in fibroblasts isolated from patients with ALS. LOC100129198 transcript was present at significantly higher levels in ALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of ALS.
The Place of Non-Governmental Organizations in the Turkish Education System According to Social Studies Teachers
Authors: Bozkaya Hasan
Published: September 2022

In this research, the place of non-governmental organizations in the Turkish education system was tried to be determined according to the opinions of social studies teachers. Phenomenology design was used from qualitative research methods. The study group of the study consists of 37 social studies teachers selected from schools in Hatay city center through purposeful sampling. Four open-ended questions prepared to collect data were asked to social studies teachers for their opinions. In the analysis of the obtained data, the content analysis method used in qualitative analysis researches was applied and themes were created by grouping according to the similarity of the expressions. The teacher's views that stand out in each theme are reflected in direct quotes. According to the results obtained from the opinions of social studies teachers at the end of the research; It was concluded that non-governmental organizations are necessary but not sufficiently supported by the society, and that non-governmental organizations are not sufficiently involved in education policies and practices, that they remain insensitive in solving the problems related to education and that they cannot express these problems sufficiently.
THE IMPLEMENTATION OF PRODUCTIVE WAQF IN PESANTREN GONTOR
Authors: triyawan andi
Published: September 2022

This paper discusses productive waqf and the uniqueness of the application of productive waqf management in a pesantren (Islamic boarding school). Furthermore, the standardisation of the law used in the implementation of the productive waqf, which includes al-Qur'an, Hadits, fiqh rules, and aqwâl al-'ulamâ, must be examined in order to reach a conclusion on the implementation status. There are many unique things to analyze in the implementation, such as the use of the institution fund, which is oriented to develop cash waqf, and the exictence of the waqf board, which becomes the highest decision maker. Because all of the pesantren's assets become waqf property, the highest leader is no longer on the foundation but on the waqf board.
Pengaruh Pergaulan Bebas Bagi Remaja Terhadap Perilaku Sehari-Hari Yang berhubungan Dengan Sila Ke-2 Pancasila
Authors: Laksono Maulana Ari
Published: September 2022

Masa remaja adalah masa yang paling menonjol di kalangan masyarakat. Dimana remaja tersebut dituntut untuk mencari jati dirinya masing-masing, banyak para remaja terjebak di pergaulan bebas, di masa remaja harus mendapatkan perhatian khusus dari diri sendiri, orang tua, dan masyarakat. Pergaulan bebas merupakan perilaku negatif yang tidak boleh ditiru, dan melanggar suatu aturan-aturan, norma yang berlaku pada sila ke-2 Pancasila dan agama. Di era masa kini pergaulan dipandang sebelah mata oleh para remaja dan menjadi trend masa kini, bila remaja tersebut jika tidak mengikuti trend dia merasa kurang keren di era masa kini. Dampak dari pergaulan bebas mempengaruhi pada diri sendiri, orang tua, dan negara. Seperti terpengaruhnya obat-oabatan, menyebarnya penyakit HIV, hamil di luar nikah, dan berbagai macam yang mempengaruhi kesehatan.
23, the German 'Hackers' (historiography VI:9 - part one)
Authors: Akmut Camille
Published: September 2022

Computer science and technology : historiography VI (9 - part one). Karl Koch special issue
The definition of the self
Authors: Mentzou Aikaterini
Published: September 2022

This essay explores key philosophical perspectives on the definition of what is the self.
Infant phonetic learning as perceptual space learning: A crosslinguistic evaluation of computational models
Authors: Matusevych Yevgen , Schatz Thomas , Kamper Herman , Feldman Naomi , Goldwater Sharon
Published: September 2022

In the first year of life, infants' speech perception becomes attuned to the sounds of their native language. This process of early phonetic learning has traditionally been framed as phonetic category acquisition. However, recent studies have hypothesized that the attunement may instead reflect a perceptual space learning process that does not involve categories. In this article, we explore the idea of perceptual space learning by implementing five different perceptual space learning models and testing them on three phonetic contrasts that have been tested in the infant speech perception literature. We reproduce and extend previous results showing that a perceptual space learning model that uses only distributional information about the acoustics of short time slices of speech can account for at least some cross-linguistic differences in infant perception. Moreover, we find that a second perceptual space learning model which benefits from word-level guidance performs equally well in capturing cross-linguistic differences in infant speech perception. These results provide support for the general idea of perceptual space learning as a theory of early phonetic learning, but suggest that more fine-grained data is needed to distinguish between different formal accounts. Finally, we provide testable empirical predictions of the two most promising models and show that these are not identical, making it possible to independently evaluate each model in experiments with infants in future research.
Optimising the measurement of anxious-depressive, compulsivity and intrusive thought and social withdrawal transdiagnostic symptom dimensions
Authors: Hopkins Alexandra Kathryn , Gillan Claire , Roiser Jonathan Paul , Wise Toby , Sidarus Nura
Published: September 2022

Transdiagnostic mental health factors measuring anxious-depressive, compulsivity and intrusive thought and social withdrawal symptom dimensions have been identified as useful constructs that relate to a variety of cognitive constructs. However, the factor measurement relies on the administration of hundreds of questionnaire items which is both costly and a burden to participants. Additionally, it is unclear to what extent these factors generalise across datasets. Therefore, this study sought to optimise the measurement as well as assess the stability of these three factors. Using exploratory factor analysis on 209 questionnaire items, we replicated the same three-factor structure across a pooled dataset of n = 4782 participants, as well as within four independent subsets of the data. Using a machine learning approach, we reduced the number of items to 71 while still measuring the factors with high accuracy. We externally validated these factor scores by replicating previously observed associations with behaviour on a metacognition task. Our results support the generalisability of these symptom dimensions and provide a useful approach to optimising their measurement.
Fake News in Social Networks
Authors: Aymanns Christoph , Foerster Jakob , Georg Co-Pierre , Weber Matthias
Published: September 2022

We propose multi-agent reinforcement learning as a new method for modeling fake news in social networks. This method allows us to model human behavior in social networks both in unaccustomed populations and in populations that have adapted to the presence of fake news. In particular the latter is challenging for existing methods. We find that a fake-news attack is more effective if it targets highly connected people and people with weaker private information. Attacks are more effective when the disinformation is spread across several agents than when the disinformation is concentrated with more intensity on fewer agents. Furthermore, fake news spread less well in balanced networks than in clustered networks. We test a part of these findings in a human-subject experiment. The experimental evidence provides support for the predictions from the model. This suggests that our model is suitable to analyze the spread of fake news in social networks.
Crop Establishment Methods, Varieties and Levels of Zinc on Growth and Yield of Rice in Chitwan, Nepal
Authors: Pariyar Rajan , Shah Shrawan K. , Marahatta Santosh , Karki Tika B.
Published: September 2022

With the aim of identifying the appropriate doses of Zinc in rice for different varieties under various establishment methods, an experiment was carried out in a strip-split plot design with three replications at Agriculture and Forestry University, Rampur, Chitwan during 2015-16. The treatment consists of two crop establishment methods (Transplanted rice (TPR) and Direct Seeded Rice (DSR)) in the vertical strip and two varieties (Hybrid Gorakhnath-509 and Sabitri) in the horizontal strip and four levels of ZnSO4 (0, 15, 30 and 45 kg ha-1) in sub-sub plot. The observations were recorded on growth, yield attributes, grain yield and economics. The research results revealed that the application of ZnSO4 @ 15 Kg ha-1 significantly increased the grain yield of DSR as compared to the non-application of ZnSO4. The higher grain yield of rice was because of increased yield attributes like effective tillers, thousand-grain weight and the number of filled grains per panicle. Crop establishment methods and varieties did not have a significant influence on the grain yield of rice. DSR had a lower cost of cultivation, higher net return and higher benefit-cost ratio as compared to TPR. The variety Sabitri had lower cost of cultivation, higher net return and higher benefit-cost ratio as compared to Gorakhnath-509. Similarly, the application of ZnSO4 @ of 15 Kg ha-1 produced the highest net return and the highest  benefit-cost ratio. Therefore,  ZnSO4 @ 15 kg ha-1 could be an option for increased yield and net return for DSR in Chitwan.