bluuebunny/crossref_metadata_2025 huggingface dataset:
Digestibility of amino acids in fish meal and blood-derived protein sources fed to pigs
Authors: Park Chan Sol , Adeola Olayiwola
Published: January 2022

Objective: An experiment was conducted to determine the standardized ileal digestibility (SID) of amino acids (AA) in fish meal (FM) and blood-derived protein sources including spray-dried porcine plasma (SDPP), porcine red blood cells (PRBC), and blood meal (BM) fed to growing pigs.Methods: Ten barrows (mean initial body weight of 22.1±1.54 kg) surgically fitted with T-cannulas at the distal ileum were allotted to a duplicated 5×4 incomplete Latin square design with 5 experimental diets and 4 periods. Four experimental diets were prepared to contain FM, SDPP, PRBC, or BM as the sole source of nitrogen. A nitrogen-free diet was prepared and included to estimate the basal ileal endogenous losses of AA. For the 7-day experimental period, pigs were fed for 5 days as adaptation, and ileal digesta samples were collected for 9 hours on days 6 and 7.Results: The SID of crude protein in BM (48.0%) was less (p<0.05) than in FM, SDPP, and PRBC (83.4%, 83.9%, and 87.3%, respectively). Pigs fed the diet containing BM had less (p<0.05) SID of AA, except isoleucine and proline, than those fed the diet containing FM, SDPP, or PRBC. Among FM, SDPP, and PRBC, there was no difference in the SID of crude protein and all AA, except isoleucine. The SID of isoleucine in PRBC and BM (62.7% and 48.3%, respectively) was less (p<0.05) than in FM and SDPP (88.0% and 84.9%, respectively). The SID of lysine in FM, SDPP, PRBC, and BM was 85.4%, 84.9%, 89.7%, and 51.9%, respectively.Conclusion: The SID of most AA was not different among FM, SDPP, and PRBC, but BM had lower SID of most AA than FM, SDPP, and PRBC.
A disputa de Fernando Haddad e Jair Bolsonaro à presidência do Brasil em 2018
Authors: Ribeiro Andressa Dembogurski , Pozobon Rejane Oliveira
Published: January 2022

A partir do método da “análise argumentativa persuasiva” (RIBEIRO, 2019; RIBEIRO, 2019b; RIBEIRO, POZOBON, 2019), este texto apresenta as estratégias discursivas empregadas pelos candidatos Fernando Haddad e Jair Bolsonaro durante a campanha eleitoral de 2018, no Instagram. Observamos a importância da imagem como um elemento argumentativo e persuasivo nas campanhas eleitorais  em abril de 20020tipo de expressos.mo.uantos caracteres sque, junto com outras ferramentas do discurso político e do propagandista (CHARAUDEAU, 2016, 2017), integra o fazer comunicacional e  forma o que denominamos de “publicização da política”.
La pensée des femmes catholiques en Europe. Les combats de Maria Paola Colombo Svevo
Authors: MATTESINI Maria CHIARA
Published: January 2022

‘Equal pay for equal work’, ‘Action against trafficking in human beings’ and the ‘Role of cooperatives in the growth of women's employment’ are those three im­portant battles carried out by the women at the European Parliament in the 1990s. They represent greater justice, more dignity, increased democracy. In particular, the article wants to remember the figure of Maria Paola Colombo Svevo, senator of the Italian Christian-Democratic Party, member of the European People's Party and member of the European Parliament between 1995 and 1999.
Biosimilars in Inflammatory Bowel Diseases: General Concepts and Clinical Implications
Authors: Rodrigues de Figueiredo Sabrina , Elisa Rabe Caon Ana , Saad Hossne Rogerio , Vieira Teixeira Fábio , Murakami Winkler Sabine , Sousa Freitas Queiroz Natália
Published: January 2022

The treatment of inflammatory bowel disease (IBD) has changed over time with the increasing use of biologics to achieve therapeutic goals. As a result, the cost of treatment increased considerably, making it necessary to develop strategies that could increase access to biological therapies. In this scenario, the biosimilars were developed with the aim of reducing costs, maintaining safety and efficacy compared to the originator. Initially, its use in IBD was based on the extrapolation of studies in other specialties, such as rheumatology. More recently, studies in inflammatory bowel disease have emerged, with favorable results for its use. It is known that there are still knowledge gaps in the use of biosimilars and more experience is needed to increase clinicians’ confidence in their clinical practice. This chapter proposes a review of what is currently known about biosimilars in IBD. It discusses about aspects such as safety, efficacy, interchangeability, immunogenicity and switches.
Fusarium Disease of Maize and Its Management through Sustainable Approach
Authors: Tiru Zerald , Mandal Parimal , Pratim Chakraborty Arka , Pal Ayon , Sadhukhan Sanjoy
Published: January 2022

Fusarium causing disease in maize is probably the one of the most serious diseases among the crop plants all over the world. It not only damages the maize plant, reduces its potential yield and its nutritional values but imposes threatening to the human life through the induction of mycotoxin development. F. graminearum and F. moniliforme syn. Fusarium verticillioides are two important maize pathogens that cause substantial damage to its ear, stalk and foliage, causing contamination of grains with mycotoxins. Since conventional methods of controlling the diseases including the chemical methods proved not enough for total control of the disease with creating situation even worse for our surroundings, the application of PGPR and PGPF can play significant role to control the damage caused by Fusarium.
University Teachers’ Conceptions of What University Is: Implications for the Future of Higher Education
Authors: Chaleta Elisa
Published: January 2022

This chapter presents the perception of university teachers about the university, the most recent changes and how they have influenced their activity. The phenomenographic study was conducted with 10 university teachers, nine females and one male with more than 15 years of professional activity. The perception of the university emerges, in the teachers’ voice, focused on the description of its mission, namely as a context for the production and diffusion of knowledge to society, as a space for creative and critical thinking about the world, as an interdisciplinary space and as a system focused on teaching and research. It also includes characteristics related to its structure and functioning, such as the level of hierarchization, bureaucratization, competitiveness, dehumanization and bibliometrics overvaluation. Regarding the perceived changes, they are related to the structural reforms resulting from the Bologna Process, diverse student populations, research and internationalization, new technologies, institutional cooperation, bureaucratization and relationship with the community. Teachers also revealed some dissatisfaction in the way they are experiencing university life due to the overwork resulting from the multiple tasks required in the four activity strands (teaching, research, management and extension) with an impact on quality and innovation, but in line with what the institution demands.
Properties of Tactile Sensors Based on Resistive Ink and the Dimension of Electrodes
Authors: Volf Jaromír , Novák Viktor , Ryženko Vladimír , Papežová Stanislava
Published: January 2022

This chapter presents the ongoing research, which aims to select suitable electrodes for their use in the pressure distribution measurement system Plantograf. In our research, we examine more materials, especially Yokohama conductive rubber CS57-7RSC and also conductive inks, which are represented type DZT-3 K, Graphit 33 and mixture of Loctite-Henkel conductive inks type Loctite 7004Hr and Loctite NCI 7002EC. All materials can be used as a converter between pressure and electrical quantities in the design of planar pressure transduces. We build on our previous works, where were examined the properties of conductive rubber, conductive inks and electrodes. Next part is focused on the newest results of our research. Due to the still incomplete results in the given issue, we decided to perform an extensive and original measurement of a total of 172 combinations of different electrode sizes, the ratio of conductive ink mixtures and the thickness of the applied ink layer. Thanks to this, it will be possible in the future to select a suitable combination of electrodes and inks when designing tactile pressure sensors for industrial or medical applications without the need to perform time-consuming preparatory measurements and exclude unsuitable ink-electrode combinations.
Edible Coating
Authors: Owusu-Akyaw Oduro Kofi
Published: January 2022

Postharvest losses are rampant due to lack of proper storage conditions and handling of the fresh food products. The perishable nature of fruits and vegetables makes their shelf life limited due to some extrinsic factors such as some environmental conditions and preservation conditions as well as some intrinsic factors such as respiration rate, ethylene production and transpiration. Among the other postharvest technologies available, edible coatings seems to be one novel method which has been verified to have a positive and safe approach to extending the shelf life of products. This type of packaging is made from various natural resources like polysaccharide, protein and lipid materials. Edible packaging materials can be divided into two main groups including edible coatings and edible films. It has so many benefits such as serving as a moisture barrier, oxygen scavenger, ethylene scavenger, antimicrobial properties among others. Different methods of application of the edible coating on the food materials include; dipping, spraying, brushing, layer by layer among others. There have been several verifications of the positive impact of edible coatings/films on pome fruits, Citrus fruits, Stone fruits, tropical and exotic fruits, berries, melon, tomatoes and others.
Towards the Development of the Decolonized Pedagogy for Higher Education in South Africa: A Students’ Perspective
Authors: Ethel Khuzwayo Mamsi
Published: January 2022

This chapter presents views, opinions, and perceptions about the curriculum theories that propagate educational perspectives of social injustice, cultural exclusion, supremacy, socio-economic inequality, and inequity. The data collection method was question and answer and deductive reasoning conducted in small groups in education studies classes. Pieces of information recorded in video clips during the COVID-19 lockdown were analysed through qualitative procedures, transcribing verbal data, and sorting coded categories of data. First, the frequencies of statements indicating trends in thoughts form themes classified as convergent and divergent perspectives. The interpretation of themes identified during data analysis seeks to address the problem statement in this chapter, which is the paradigm shift for a conceptualised decolonised curriculum in South Africa. Thus, the research question asked in the study is “what principles should underpin pedagogical content knowledge (PCK) of pre-service teacher education and training?” The source of data was interviews and document analysis. The synthesis of the results drawn from the raw data was based on the theoretical and conceptual framework established from the works of scholarship researchers on decolonised education. The interpretation of the findings addressing the problem statement and the research question was presented through convergent and divergent perspectives that characterise the beliefs and thoughts of students about curriculums for decolonised education in South Africa. The study highlights uncertainties about the concepts, divergent conceptual stances on decolonised education, and the lack of uniformity in the perceptions of philosophical principles or foundations of perspectives on decolonised education.
Emerging Roles of Non-Coding RNA in Neuronal Function and Dysfunction
Authors: G. Fagan Steven , Pfeiffer Shona
Published: January 2022

Advancements in RNA sequencing technologies in recent years have contributed greatly to our understanding of the transcriptome and the now widely recognized multifaceted functions of RNA. The discovery and functional analysis of an increasing number of novel small non-coding RNAs (ncRNAs) has highlighted their importance as critical regulators of gene expression and brain function. In particular, two diverse classes of ncRNAs, microRNAs (miRNAs) and tRNA-derived small RNAs (tsRNAs), are especially abundant in the nervous system and play roles in regulation of gene expression and protein translation, cellular stress responses and complex underlying pathophysiology of neurological diseases. This chapter will discuss the most recent findings highlighting the dysregulation, functions and regulatory roles of ncRNAs in the pathophysiological mechanisms of neurological disorders and their relevance as novel biomarkers of injury and therapeutic agents.
Peri-Implant Soft Tissue Augmentation
Authors: Blašković Marko , Blašković Dorotea
Published: January 2022

The peri-implant soft tissue (PIS) augmentation procedure has become an integral part of implant-prosthetic rehabilitation. Minimal width of keratinized mucosa (KM) of 2 mm is deemed necessary to facilitate oral hygiene maintenance around the implant and provide hard and soft peri-implant tissue stability. PIS thickness of at least 2 mm is recommended to achieve the esthetic appearance and prevent recessions around implant prosthetic rehabilitation. The autogenous soft tissue grafts can be divided into two groups based on their histological composition—free gingival graft (FGG) and connective tissue graft (CTG). FGG graft is used mainly to increase the width of keratinized mucosa while CTG augment the thickness of PIS. Both grafts are harvested from the same anatomical region—the palate. Alternatively, they can be harvested from the maxillary tuberosity. Soft tissue grafts can be also harvested as pedicle grafts, in case when the soft tissue graft remains attached to the donor site by one side preserving the blood supply from the donor region. Clinically this will result in less shrinkage of the graft postoperatively, improving the outcome of the augmentation procedure. To bypass the drawback connected with FGG or CTG harvesting, substitutional soft tissue grafts have been developed.
Perspective Chapter: Alzheimer - A Complex Genetic Background
Authors: Calabrò Marco , Crisafulli Concetta
Published: January 2022

Alzheimer is a complex, multifactorial disease with an ever increasing impact in modern medicine. Research in this area has revealed a lot about the biological and environmental underpinnings of this disease, especially its correlation with Β-Amyloid and Tau related mechanics; however, the precise biological pathways behind the disease are yet to be discovered. Recent studies evidenced how several mechanisms, including neuroinflammation, oxidative stress, autophagy failure and energy production impairments in the brain, −--- have been proposed to contribute to this pathology. In this section we will focus on the role of these molecular pathways and their potential link with Alzheimer Disease.
Evaluation of Trans-Resveratrol as a Treatment for Periodontitis
Authors: Lynn Harney Tracey
Published: January 2022

Periodontitis is a globally prevalent inflammation-mediated disease that can result in varying degrees of destruction to the tissues supporting the teeth. The microbial pathogenic dysbiosis, oxidative stress, and deregulated inflammation, found in patients with periodontitis, make it a multifaceted condition that is difficult to fully resolve. Further to this, periodontitis has been associated with other systemic inflammatory conditions. Trans-resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a plant-derived molecule present in many foods, which have been shown to exhibit antimicrobial, antioxidant, anti-inflammatory, and regenerative properties. However, trans-resveratrol has been reported to have physicochemical shortcomings, which make its clinical translation a challenge. This review outlines a critical analysis of identified samples from the scientific literature that was conducted to assess the potential of RES as a viable therapeutic for periodontitis. The potential for the improvement of the limiting pharmacological profile of trans-resveratrol via nanoformulation is also explored.
Uterine Embolization as a New Treatment Option in Adenomyosis Uteri
Authors: Tsikouras Panagiotis , Gaitatzi Fotini , Filiou Stefani , Michalopoulos Spyridon , Gerede Aggeliki , Christos Tsalikidis , Zervoudis Stefanos , Bothou Anastasia , Vatsidou Xanthi , Chalkidou Anna , Dragoutsos Georgios , Tsirkas Ioannis , Nikolettos Konstantinos , Alexiou Alexios , Babageorgaka Irine , Sachnova Natalia , Panagiotopoulos Nikolaos , Nalbanti Theopi , Simeonidis Panagiotis , Kritsotaki Nektaria , Stylianou Chrysovalantis , Vasilopoulos Anastasios , Perende Sebaidin , Peitsidis Panagiotis , Nikolettos Nikolaos , Souftas Vasileios
Published: January 2022

Adenomyosis is characterized by the development of endometrial ectopic glands and tissue in the myometrium layer in depth greater than 2.5 mm from the endometrial surface of the separative area by -myomas well as by hypertrophy and hyperplasia of the smooth muscles of the myometrium. This is filtration, not mere displacement, of the myometrium, from the endometrium. Clinical symptoms include dysmenorrhea and menorrhagia. It is diffuse (adenomyosis) or focal (adenomyoma), asymmetrically affects the uterine wall of premenopausal women (usually the posterior) and often coexists with myomas. The pathogenesis of adenomyosis remains unknown. The treatment options are: drug therapy, invasive treatment of fibroids: myomectomy (open—intra-abdominal, laparoscopic, hysteroscopic), hysterectomy, myolysis—cryocatalysis, microwave or radiofrequency thermal catalysis (RF-ablation), ultrasound focus catalysis (FUS), laser photocatalysis and percutaneous selective uterine artery embolization (UAE). Embolization remains an alternative and not a substitute of hysterectomy. The medical indication is made on a case-by-case basis, depending on age, desire for pregnancy and the clinical symptoms of adenomyosis.
Association between Human Papillomavirus and Urological Cancers: An Update
Authors: Sarier Mehmet
Published: January 2022

Human papillomavirus (HPV) is currently the most common sexually transmitted pathogen in the world, and as such imposes a substantial global burden due to its oncogenic properties. The significant association of HPV with anogenital and head and neck carcinomas is well established. In terms of urological malignancies, only the association between HPV and penile cancer has been well defined; despite close anatomical proximity, its relationship with bladder, prostate, kidney, and testicular cancers has remained unclear. With technological advances in the nucleic acid amplification tests used to detect HPV over the last two decades, the results of new studies have led to the need to reexamine these relationships. This brief review aims to evaluate the association between urological malignancies and HPV infection in light of recent data.
Golden Rice, VAD, Covid and Public Health: Saving Lives and Money
Authors: C. Dubock Adrian , Wesseler Justus , M. Russell Robert , Chen Chen , Zilberman David
Published: January 2022

On July 21, 2021, Golden Rice was registered in the Philippines allowing cultivation and consumption. Research, as an intervention to combat vitamin A deficiency (VAD), started in 1991, and proof of concept for what was to become Golden Rice, was achieved in 1999. In the 1990s, 23–34% deaths globally of children less than 5 years old were caused by VAD, and in developing countries, the percentage was even higher. By 2013, progress against the Millennium Development Goals had reduced <5-y child deaths globally from VAD to about 2% of all such deaths. The progress included significant vaccination programs against measles, and better access to clean water, as well as vitamin A supplementation, all delivered through community health programs. Economic development and education about diet reduced food insecurity. In contrast to continuing VAD deaths, the Covid-19 pandemic has attracted huge political attention, including in low- and middle-income countries. Community health programs have been adversely affected by the pandemic. There is a danger that as a result VAD rates, child and maternal mortality climbs again toward 1990’s levels. Adoption of Golden Rice provides a safe, culturally simple amelioration and is costless. Other countries should seize the opportunity. Bangladesh is first in line, possibly followed by Indonesia and India.
Biogas Production: Evaluation and Possible Applications
Authors: Beschkov Venko
Published: January 2022

Biogas is an excellent example of renewable feedstock for energy production enabling closure of the carbon cycle by photosynthesis of the existing vegetation, without charging the atmosphere with excessive carbon dioxide. The present review contains traditional as well as new methods for the preparation of raw materials for biogas production. These methods are compared by the biogas yield and biogas content with the possible applications. Various fields of biogas utilization are discussed. They are listed from simple heating, electricity production by co-generation, fuel cell applications to catalytic conversions for light fuel production by the Fischer-Tropsch process. The aspects of carbon dioxide recycling reaching methane production are considered too.
A Systematic Study on TRIZ to Prepare the Innovation of 3DPVS
Authors: Yuan Haobo
Published: January 2022

Regarding the innovation of biomimetic cell culture scaffold, 3DPVS, namely 3D printed vibratory scaffold, has been proposed as a present-to-future novel product. It currently stands at the stage of conceptual development. Design studies on 3DPVS Concept Generation show high value, and one essential part inside this could dwell at establishing design methodological knowledge that has innovation merits. TRIZ with its tools has proven value on creation and design innovativeness while they have not yet been utilized for scaffold design at mature level. In this paper, we attempt to study and explore the design aspects of TRIZ and its most relevant tools on the context of 3DPVS, as well as preliminarily indicating a TRIZ-based methodology, which could tailor the design aspects of 3DPVS. It also, to some extent, fills a gap in scaffold engineering and TRIZ literature and provides a comprehensive overview of a timely topic.
Imaging of Vascular Aphasia
Authors: Duron Loïc , Lecler Augustin , Cătălin Jianu Dragoș , Sadik Raphaël , Savatovsky Julien
Published: January 2022

Brain imaging is essential for the diagnosis of acute stroke and vascular aphasia. Magnetic resonance imaging (MRI) is the modality of choice for the etiological diagnosis of aphasia, the assessment of its severity, and the prediction of recovery. Diffusion weighted imaging is used to detect, localize, and quantify the extension of the irreversibly injured brain tissue called ischemic core. Perfusion weighted imaging (from MRI or CT) is useful to assess the extension of hypoperfused but salvageable tissue called penumbra. Functional imaging (positron emission tomography (PET), functional MRI (fMRI)) may help predicting recovery and is useful for the understanding of language networks and individual variability. This chapter is meant to review the state of the art of morphological and functional imaging of vascular aphasia and to illustrate the MRI profiles of different aphasic syndromes.
Antimicrobial Resistance in Escherichia coli
Authors: Ullah Waheed , Ali Shandana
Published: January 2022

The ability of microbes to resist or neutralize the action of drugs that have been used against microbes is considered as antimicrobial resistance (AMR). AMR among different strains of Escherichia coli is considered as a major threat to public health. Drug-resistant in E. coli is found predominantly in the hospital sittings, in the community, and surrounding environment. It has adopted different defensive strategies to minimize the effects of drugs. Extended-spectrum β-lactamase (ESBL), fluoroquinolones, and carbapenemases have been considered as strong resistance strategies being present in most of resistant bacterial strains. Mobile genetic elements (MGEs) have the major contribution in the transfer of resistance genes in between or among bacterial cells. Plasmids are normally present in most of resistant strains, helping in the transfer of genetic material between bacterial cells. Transposons another MGEs, are being considered as one of the major sources of resistance transmission. Collectively, MGEs play an important role in facilitating in exchange, acquisition, and dissemination of resistance genes. Resistance in E. coli has been reported worldwide and there is variation in its resistance pattern. CTX-M ESBLs, carbapenems, colistin-resistant, and ST-131 E. coli resistant clones are considered the most dominant phenotypes. The aforesaid resistant variants are predominantly found in densely populated regions, Sub-Saharan Africa, China, and South Asian countries.
Intervention of Yoga in Stress, Anxiety and Depression
Authors: Nanthakumar Chandra
Published: January 2022

Yoga is not only an art but also an ancient science that evolved more than 5000 years ago. It is practised by people from all walks of life in almost every part of the world. In the past, the practice, which was seen to be spiritual and divine, used to be confined to smaller groups of individuals who were seeking moksha or liberation; however, the trend has transformed over the decades. Today, there are so many yoga studios worldwide, and this has made it easy for yoga enthusiasts. This chapter investigates the effectiveness of yoga not only as a complementary therapy but also as a viable option in the management of stress, anxiety and depression. Articles were retrieved using PubMed, MEDLINE and PsychInfo databases. The findings reveal that the practice of yoga as a complementary therapy and stand-alone therapy is effective in managing stress, anxiety and depression. However, further research is needed as all the studies reviewed were limited in terms of heterogeneity, sample size, intervention styles, frequency and duration of practice, and also teaching methods. The chapter concludes with suggestions for home practice.
Disparity in Higher Education Provision Caused by Technological Capabilities of Nations during Covid-19
Authors: Pandya Bharti , Cho BooYun , Patterson Louise
Published: January 2022

During Covid-19, higher education institutions were forced to resort to emergency remote learning. The nations and higher education institutions with strong technological infrastructure and resources facilitated the provision of education and caused minimal interruption in teaching and learning. While the nations with poor technological infrastructure and non-availability of resources had to struggle to continue providing the education. This study, utilizing the job-demand resources model, provided insights into the influence of technological capabilities in providing higher education during the Covid-19 period and how a disparity is caused between different nations. The findings will benefit education policy developers and leaders of higher education institutions.
Aging Associated Specificity in Training Visual Short-Term Memory
Authors: Razumnikova Olga , Kagan Vladislav
Published: January 2022

There are numerous data in existence, the computerized cognitive training programs (CCTP) maintain or improve the plasticity of the neural networks in the brain. It is known as well that CCTP reduces the probability of cognitive dysfunctions associated with aging. In the chapter, the age-associated specificity in the temporal dynamics of changes in the visuospatial short-term memory (VSWM, also called visuospatial working memory) is presented. VSWM has been analyzed as there are evidence for age-related decline in visuospatial memory associated with hippocampus atrophy in aging. Memory retrieval decline in older women in comparison with young women while computerized training at home is shown. The elderly achieving results which are comparable to the youngs are determined by significantly increased duration while performing the memory tasks. To reveal factors of the CCTP’s efficiency, age-related differences in the attention systems using the Attention Network Test were resolved. In the group of older women, VSWM efficiency is negatively related to the errors of incongruent information selection whereas in young women—to the reaction time while testing. Thus, the success of long-term systematic training of visuospatial memory in old age is strongly related to the high level of executive control.
Creating Communities of Parents
Authors: Skjesol Ingunn
Published: January 2022

Norwegian Open Kindergartens facilitate access to professional advice and peer support, supporting parents to take part in collective learnings processes, renegotiate their roles and build social networks. Drawing on a study of five Open Kindergartens located in three Norwegian municipalities, this book chapter discusses how these spaces create opportunities to develop parenting skills and negotiate what it means to be a parent. Open Kindergartens are drop-in meeting places where parents and children take part in everyday activities as part of a diverse group. Open Kindergartens provide a space to learn parenting by doing, in a safe and non-judgmental environment, facilitated and supported by a range of professionals. This approach supports integration in local communities and contrasts with many parenting programs that are professionally led and often highly normative.
Process Management: A Requirement for Organizational Excellence in the Twenty-First Century Business Environment?
Authors: Kalala Ndalamba Ken , do Rosário Botelho Tomé Euzália
Published: January 2022

The purpose of this study is to define process management as a requirement of organizational excellence in the twenty-first century business environment. The business environment in the twenty-first century has reached a new height as far as challenges are concerned. The Covid-19 pandemic and its consequences have shaped a new business environment that requires organizations and businesses to raise the bar for themselves in honoring their obligation to achieve excellence. This means that competitive advantage, quality service, and product are achieved through organizational excellence. How can process management help organizations and businesses achieve organizational excellence in such a hostile and turbulent business environment? Applying a conceptual approach, the study attempts to answer the question through a comprehensive literature review. Testable propositions have been formulated, action steps defined, and implications of the study established. By identifying workflow design (WFD), control and correction of workflow processes (CCWFP), monitoring of workflow processes (MWFP), and workflow promotion of process-related learning in organizations (WPPRLO) against the background of conceptualization, operationalization, and context, the study findings suggest that process management is indeed a requirement for organizational excellence in the twenty-first century business environment. Scholars and practitioners have the opportunity to confirm or disconfirm the validity of the assumptions and ideas presented in the study.
Thermoelectric Elements with Negative Temperature Factor of Resistance
Authors: Bokhan Yuri
Published: January 2022

The method of manufacturing of ceramic materials on the basis of ferrites of nickel and cobalt by synthesis and sintering in controllable regenerative atmosphere is presented. As the generator of regenerative atmosphere the method of conversion of carbonic gas is offered. Calculation of regenerative atmosphere for simultaneous sintering of ceramic ferrites of nickel and cobalt is carried out. It is offered, methods of the dilated nonequilibrium thermodynamics to view process of distribution of a charge and heat along a thermoelement branch. The model of a thermoelement taking into account various relaxation times of a charge and warmth is constructed.
Minimally Invasive Treatment for Cholelithiasis
Authors: Okamoto Hirotaka
Published: January 2022

Gallstone disease, cholecysto- and choledocho-lithiasis, is one of the most common digestive diseases. Most patients with symptomatic cholecystolithiasis are recommended to undergo cholecystectomy to alleviate their symptoms like abdominal pain and jaundice. Approximately 10–20% of patients who undergo cholecystectomy for gallstones have choledocholithiasis. Nowadays, endoscopic and/or laparoscopic approaches are widely accepted as the treatment for patients with gallstone. Patients with cholecystolithiasis are usually treated by laparoscopic cholecystectomy, whereas patients with choledocholithiasis are done by endoscopic sphincterotomy (EST) or laparoscopic common bile duct exploration (LCBDE). Additionally, some cases are treated by biliary reconstruction such as biliary enteric anastomosis. In this chapter, currently available laparoscopic approaches as a minimally invasive surgery are introduced and discussed on the basis of pathogenesis of the gallstone.
Insomnia and its association with absenteeism: A cross-sectional study among Iranian nursing team
Authors: Sadeghniiat-Haghighi Khosro , Najafi Arezu , Eftekhari Sahar , Tarkhan Samareh
Published: January 2022

Objective Given the potential impact of insomnia on nurses’ performance, it is assumed that insomnia is associated with their absence from work. The present study aimed to determine the insomnia status and its association with absenteeism among a selective group of Iranian healthcare providers.

Material and Methods This cross-sectional study was conducted on 304 healthcare providers working at Imam-Khomeini hospital complex in Tehran. The study population were assessed by insomnia severity index for characterization of insomnia symptoms. The data of absenteeism was collected from the employees’ attendance system of hospital’s nursing and staff department. The multivariable linear regression model used for predicting determinants of insomnia and absenteeism in nursing team.

Results Different degrees of insomnia was found in 79.9% of the study population, which 57.2% suffered from mild insomnia, 21.4% from moderate insomnia, and 1.3% from severe insomnia. The prevalence of insomnia was significantly higher in persons who were absent from their workplace frequently, or left because of illness. The mean days for total absenteeism in healthcare workers with moderate to severe insomnia was significantly higher than others with mild and no insomnia. In multivariate analysis, having night shifts and the severity of insomnia could predict absenteeism in studied population.

Discussion A majority of healthcare workers suffer from insomnia that may lead to their work absenteeism and decreased performance. Proper administrative and individuals for management of sleep problems is required to avoid long hours of absenteeism among nursing team.
Prevalence, pattern and impact of sleep disturbance on quality of life and exercise participation among children with cerebral palsy in Kano city
Authors: Badaru Umaru M. , Hassan Aliya M. , Ahmad Rufai Y. , Nuhu Jibril M. , Lawal Isa U.
Published: January 2022

Introduction Sleep disturbance (SD) could have negative impact on the general well-being of children with cerebral palsy (CWCP).

Objectives The purpose of this study was to assess the prevalence of SD and its impact on quality of life and exercise participation among CWCP.

Material and Methods In the cross-sectional study, CWCP and their siblings were recruited from secondary and tertiary hospitals in Kano City. SD, gross motor function (GMF), spasticity and quality of life were assessed with SD scale, GMF classification system, modified Ashworth scale and pediatric quality of life inventory, respectively. Data was analyzed with Mann-Whitney U and chi-square tests, linear and hierarchical regressions using SPSS version 20.0.

Results There were 200 CWCP (aged 4.35±8.03 years) and 200 siblings (aged 5.89±3.06 years). The prevalence of SD in CWCP was 31.5%. CWCP suffered more SD than their siblings (p<0.001). SD in CWCP is influenced by GMF level (ß=0.378, p<0.001) and gender (ß=0.16, p<0.05). SD has negative influence on quality of life (ß=-0.18, p<0.001), active participation in home-based (ß=-0.23, p<0.000), and clinic-based exercises (ß=-0.24, p<0.00). GMF levels (ß=-0.505, p<0.0001), hamstring spasticity (ß=-0.250, p<0.005), and age (ß=-0.207, p<0.001) also have influenced on quality of life.

Conclusion One-third of the CWCP suffered pathologic SD, which has negative impact on their quality of life and the ability to actively participate in both home and clinic-based exercises. Aside SD, other factors such as child’s age, spasticity level and severity of motor impairment also affected their quality of life negatively. Enhancing the motor abilities of CWCP may improve their quality of sleep and quality of life.
Riesgo de diabetes mellitus tipo 2 y sus determinantes
Authors: Heredia Mariel , Gallegos Cabriales Esther Carlota
Published: January 2022

Objective: Describe the relationship between social determinants of health and risk of type 2 diabetes mellitus in Mexican population.Methods: This was a cross-sectional descriptive correlational study of a sample of 256 individuals from a rural community in Sinaloa, Mexico. Data collection was carried out from October 2020 to February 2021. A snowball non-probability sampling method was used. The Instruments used were the International Physical Activity Questionnaire (IPAQ), short version, the IPAQ-A for adults, the IPAQ-C for children, and a sociodemographic, anthropometric, and clinical data sheet.Results: The most frequent risk indicators for T2DM for adults are hypertension (81.7%) and overweight/obesity (68.6%); in children, it was overweight/obesity (34.9%). The risk of T2DM increased according to age (r = .560, p < .01) but decreased as education level increased (r = −.127, p < .05)Conclusions: The approach to T2DM risk factors from the perspective of social determinants of health allows strategic healthcare planning that considers the contextual factors associated with a lifestyle that reinforces the actions of healthcare providers.

Objetivo: Describir la relación de los determinantes sociales de salud con el riesgo de DMT2 en población mexicana.Métodos: Estudio descriptivo correlacional transversal, con una muestra de 256 individuos de una comunidad rural de Sinaloa, México. La recolección de datos se realizó durante octubre de 2020 y febrero de 2021. El muestreo fue no probabilístico por bola de nieve. Los instrumentos utilizados fueron el cuestionario internacional de actividad física (IPAQ) versión corta, IPAQ-A, IPAQ-C y una hoja de registro datos sociodemográficos, antropométricos y clínicos.Resultados: Los indicadores de riesgo de DMT2 con mayor frecuencia para adultos fue padecer hipertensión arterial (81.7%) y SP/OB (68.6%) y para menores de edad fue tener SP/OB (34.9%). Resultó que el riesgo de DMT2 se acrecentaba según lo hacía la edad (r = .560, p < .01) pero disminuía al aumentar la escolaridad de las personas (r = -.127, p < .05).Conclusiones: El abordaje de factores de riesgo de DMT2 bajo la perspectiva de los DSS brinda la oportunidad de plantear estrategias de salud que contemplen factores contextuales simultáneos al estilo de vida que refuercen las acciones del personal de salud para contribuir a la reducción de los índices de morbimortalidad causados por la DMT2.
Efecto de un programa de acondicionamiento físico supervisado virtualmente sobre la condición física y el estrés percibido en docentes universitarios durante el confinamiento por COVID-19
Authors: Manito Quintero Alejandro , Barranco Ruiz Yaira
Published: January 2022

The objective of this study was to analyze the effect of a virtually supervised fitness program on physical fitness and perceived stress in university teachers during lockdown due to COVID-19. A total of 15 university teachers participated in a virtual fitness program based on new fitness trends (4-weeks / 2-days / week / 45-minutes / session) during COVID-19 lockdown. Perceived physical fitness using the International-Fitness-Scale (IFiS) and perceived stress using the Perceived-Stress-Questionnaire (PSQ-30) were evaluated pre and post intervention. The virtual fitness program significantly improved the perception of general physical fitness (p = 0.011) and muscle strength (p = 0.024), and generated a significant decrease in the perception of stress (p <0.001). A virtually supervised fitness program based on the “whole-body HIIT” fitness trend could be an effective strategy to ensure healthy levels of physical fitness and stress in university teachers during confinement situations.

El objetivo de este estudio fue analizar el efecto de un programa de acondicionamiento físico supervisado virtualmente sobre la condición física y el estrés percibido en docentes universitarios durante la situación de confinamiento por COVID-19. Un total de 15 docentes universitarios participaron un programa de acondicionamiento físico virtual basado en nuevas tendencias fitness (4-semanas/2-días/semana/45-minutos/sesión) durante el confinamiento por COVID-19. La condición física percibida mediante la International-Fitness-Scale (IFiS) y el estrés percibido mediante el Perceived-Stress-Questionnaire (PSQ-30) fueron evaluados pre y post intervención. El programa de acondicionamiento físico virtual mejoró significativamente la percepción de la condición física general (p=0,011) y de la fuerza muscular (p=0,024), y generó una disminución significativa de la percepción de estrés (p<0.001). Un programa de acondicionamiento físico supervisado virtualmente basado en la tendencia fitness “HIIT whole-body” podría ser una estrategia eficaz para garantizar niveles saludables de condición física y estrés en docentes universitarios durante situaciones de confinamiento.
TIC como herramientas didácticas para el profesorado de educación física en la formación reglada utilizando el modelo Flipped Classroom
Authors: Espejo García R. , Infantes Rojas B. , Moya Medina M.A. , Morente-Oria H.
Published: January 2022

ICTs are tools present in our life's areas, the rise of which has led to their introduction in the educational curriculum and in teaching as a key and indispensable part of it. Thanks to scientific advancement, performance measurement devices are becoming more frequent and easy to use by professionals in physical activity and sports. Therefore, the present work aims to make a didactic proposal based on the use of ICT as a methodological strategy and tool for assessing and implementing training programs within the curricular framework of the educational stage Professional Training of the Higher Technician in Physical Conditioning. This proposal will consist of seven sessions for the subject of "Assessment of the physical condition and intervention in accidents" where they will handle digital tools that favor developing their objectives and skills and integration into the professional market.

Las TIC son una herramienta presente en todos los ámbitos de nuestra vida, cuyo auge ha provocado su introducción en el currículum educativo y en las enseñanzas como una pieza clave e indispensable del mismo. Gracias al avance científico, el uso de dispositivos para la medición del rendimiento es cada vez más frecuente y fácil de usar por parte de profesionales de la actividad física y del deporte. Por eso, el presente trabajo tiene como objetivo realizar una propuesta didáctica basada en el uso de las TIC como estrategia metodológica y herramienta para la valoración y realización de programas de entrenamiento dentro del marco curricular de la etapa educativa Formación Profesional del Técnico Superior en Acondicionamiento Físico. Esta propuesta estará compuesta por siete sesiones para la asignatura de “Valoración de la condición Física e intervención en accidentes” donde manejarán herramientas digitales que favorezcan el desarrollo de sus objetivos y competencias e integración en el mercado profesional.
Is the Group Structure Important in Grouped Functional Time Series?
Authors: Yang Yang , Shang Han Lin
Published: January 2022

We study the importance of group structure in grouped functional time series. Due to the non-uniqueness of group structure, we investigate different disaggregation structures in grouped functional time series. We address a practical question on whether or not the group structure can affect forecast accuracy. Using a dynamic multivariate functional time series method, we consider joint modeling and forecasting multiple series. Illustrated by Japanese sub-national age-specific mortality rates from 1975 to 2016, we investigate one- to 15-step-ahead point and interval forecast accuracies for the two group structures.
Transcriptional regulation of neural stem cell expansion in the adult hippocampus
Authors: Guo Nannan , McDermott Kelsey D , Shih Yu-Tzu , Zanga Haley , Ghosh Debolina , Herber Charlotte , Meara William R , Coleman James , Zagouras Alexia , Wong Lai Ping , Sadreyev Ruslan , Gonçalves J Tiago , Sahay Amar
Published: January 2022

Experience governs neurogenesis from radial-glial neural stem cells (RGLs) in the adult hippocampus to support memory. Transcription factors (TFs) in RGLs integrate physiological signals to dictate self-renewal division mode. Whereas asymmetric RGL divisions drive neurogenesis during favorable conditions, symmetric divisions prevent premature neurogenesis while amplifying RGLs to anticipate future neurogenic demands. The identities of TFs regulating RGL symmetric self-renewal, unlike those that regulate RGL asymmetric self-renewal, are not known. Here, we show in mice that the TF Kruppel-like factor 9 (Klf9) is elevated in quiescent RGLs and inducible, deletion of Klf9 promotes RGL activation state. Clonal analysis and longitudinal intravital two-photon imaging directly demonstrate that Klf9 functions as a brake on RGL symmetric self-renewal. In vivo translational profiling of RGLs lacking Klf9 generated a molecular blueprint for RGL symmetric self-renewal that was characterized by upregulation of genetic programs underlying Notch and mitogen signaling, cell cycle, fatty acid oxidation, and lipogenesis. Together, these observations identify Klf9 as a transcriptional regulator of neural stem cell expansion in the adult hippocampus.
Genome-wide identification and expression profile of YABBY genes in Averrhoa carambola
Authors: Li Chengru , Dong Na , Shen Liming , Lu Meng , Zhai Junwen , Zhao Yamei , Chen Lei , Wan Zhiting , Liu Zhongjian , Ren Hui , Wu Shasha
Published: January 2022

Background

Members of the plant-specific YABBY gene family are thought to play an important role in the development of leaf, flower, and fruit. The YABBY genes have been characterized and regarded as vital contributors to fruit development in Arabidopsis thaliana and tomato, in contrast to that in the important tropical economic fruit star fruit (Averrhoa carambola), even though its genome is available.

Methods

In the present study, a total of eight YABBY family genes (named from AcYABBY1 to AcYABBY8) were identified from the genome of star fruit, and their phylogenetic relationships, functional domains and motif compositions, physicochemical properties, chromosome locations, gene structures, protomer elements, collinear analysis, selective pressure, and expression profiles were further analyzed.

Results

Eight AcYABBY genes (AcYABBYs) were clustered into five clades and were distributed on five chromosomes, and all of them had undergone negative selection. Tandem and fragment duplications rather than WGD contributed to YABBY gene number in the star fruit. Expression profiles of AcYABBYs from different organs and developmental stages of fleshy fruit indicated that AcYABBY4 may play a specific role in regulating fruit size. These results emphasize the need for further studies on the functions of AcYABBYs in fruit development.