bluuebunny/crossref_metadata_2025 huggingface dataset:
Qualitative description of outreach and engagement in perinatal substance treatment in Finland
Authors: Sorsa Minna , Hohenthal Maria , Pikulinsky Miia , Sellergren Hanna , Puura Kaija
Published: October 2022

Background
Women with perinatal substance problems experience barriers to care if they do not disclose their health problems. They have specific early intervention needs, they endure societal stigma, and both substances and mental health issues influence the manner how they navigate within support and treatment systems. Early interventions for women with perinatal substance problems are under-researched contexts.
Methods
We studied an early intervention program designed and aimed at reaching out to pregnant women and mothers with small children, which includes outreach and low threshold elements. The data consist of online written narratives from 11 workers involved in the program and feedback from 504 families in the recovery process comprised of 228 open-ended answers. The data were analyzed with a thematic analysis.
Results
The programs are characterized by flexibility and the implementation of new methods to approach families. The themes for enhancing relationships and engagement within outreach and low threshold programs are: Acceptance and attitude: a sensitive approach of approval; flexibility within strictness to allow for diversity and individuality; availability and space to ensure calmness in a trustful atmosphere; negotiating via doing to build connections; and everyday life changes: imagining recovery.
Conclusions
To enhance building connections between workers and women in need of intervention, the entire family situation needs to be acknowledged. Fathers’ or partners’ continuing substance abuse and women’s weak status in a world of substance abuse may make it difficult for women to enter and engage in treatment. One suggestion is to ensure long-term SUD treatment can be initiated during pregnancy. Many families will profit from outreach and low threshold services, so that they will not need to even enter long-standing recovery programs. By informing and messaging about substance-abuse services, for example on social media and other platforms, knowledge about such services will reach those in need. In addition, providing professionals with anti-stigma training and the general public with information about services and SUD treatment may mitigate the stigma related to substance-abuse treatment.
DNA methylation is involved in sex determination in spinach
Authors: Jia Keli , Duan Jiaming , Cheng Guangqian , Li Heng , Li Shufen , Hu Miao
Published: October 2022

To explore whether DNA methylation plays different roles in the spinach development of individual male and female dioecious plants, methylation sensitivity amplification polymorphism (MSAP) was used to assess differential cytosine CpG methylation profiles of CCGG motifs of the spinach. 16 pairs of amplification primers were selected, A total of 434 DNA fragments, of which 134 methylated fragments were detected in the male and female plants. The relative ratios of the methylated sites did have sex-specific differences, which was 28.8% and 33% in the male and female. In addition, 32 sex-specific cytosine methylation bands were obtained, 15 fragments were male specific and 17 fragments were female specific. The level of cytosine methylation on CCGG was higher in female genomes than male genomes. The methylation level of CG island was involved in the sex determination and the differentiation process of spinach, which provided information for revealing the sex determination of spinach.
Triangulations of Grassmannians and flag manifolds
Authors: Abawonse Olakunle S
Published: October 2022

MacPherson in\cite{macp:rob} conjectured that the Grassmannian \(\mathrm{Gr}(2, \mathbb{R}^n)\) has the same homeomorphism type as the combinatorial Grassmannian \(\mbox{MacP}(2,n)\) , while Babson\cite{bab:eric} proved that the spaces \(\mbox{Gr}(2,\mathbb{R}^n)\) and \(\mbox{Gr}(1,2,\mathbb{R}^n)\) are homotopy equivalent to their combinatorial analogs, the simplicial complexes \(\|\mbox{MacP}(2,n)\|\) and \(\|\mbox{MacP}(1,2,n)\|\) respectively. We will prove that \(\mbox{Gr}(2, \mathbb{R}^n)\) and \(\mbox{Gr}(1,2, \mathbb{R}^n)\) are homeomorphic to $\|\mbox{MacP}(2,n)\|$ and $\|\mbox{MacP}(1,2,n)\|$ respectively
Spatial and temporal variation of floral visitors and their visitation pattern on Acanthus ilicifolius L.: A case study from the Indian Sundarbans
Authors: CHATTERJEE TANIA , Chakrabarty Souparna , Roy Sankarsan , Biswas Olive , Mitra Bulganin , Chaudhuri Punarbasu
Published: October 2022

Acanthus ilicifolius is a spiny semi-woody evergreen shrub which is one of the most dominant mangrove associate species. Although its floral biology is well documented, there is not enough systematic study of floral visitors of this species. Successful plant reproduction is highly dependent on plant-pollinator interaction. The present study aims to understand the range of floral visitors of A. ilicifolius and their spatio-temporal variation in visitation pattern from the Indian Sundarbans. This study was conducted in five islands of Sundarbans Biosphere Reserve (SBR), namely, Bali, Gosaba, Satjelia, Gangasagar and Bakkhali during 2015 and 2016. Fifteen flower visitors under five taxonomic orders, i.e., Hymenoptera, Coleoptera, Diptera, Lepidoptera and Passeriformes were identified. Seven out of these fifteen species were reported for the first time as floral visitor of A. ilicifolius. Order Hymenoptera was the most frequent insect group, whereas Apis mellifera of this order was the predominant flower visitor. Although Gangasagar and Bakkhali being tourist spots, face greater anthropogenic interference, they had the highest abundance of floral visitors. A significant variation in floral visitor abundance was observed across different time of the day throughout the study period. Floral visitors were most abundant in the morning between 8 a.m. to 12 p.m. This study provides the first comprehensive report of diversity and abundance of the floral visitors and their visitation pattern on A. ilicifolius. Implications for insect conservation: Proper documentation of the ecology of insect pollinators would automatically help to conserve the plants along with the insects, and thus preserve the entire mangrove ecosystem of the Sundarbans as well as mangroves around the world.
Detrimental Consequences after Intimal Disruption of Subclavian Artery during Transcathether Aortic Valve Implantation
Authors: Reuthebuch Oliver T. , Vasiloi Ion , Nestelberger Thomas , Wolff Thomas , Eckstein Friedrich
Published: October 2022

Background: TAVI via the left subclavian artery is considered a bail-out strategy in cases where a transfemoral approach is not feasible. However, since this route is only scarcely used, major complications can arise. We describe such an adverse course and present our proceeding.
Case presentation:A 65-year-old man with severe aortic valve stenosis (AS) was referred for transcatheter aortic valve implantation (TAVI) via left subclavian artery. After uneventful deployment of the TAVI prosthesis, consequent valve assessment with transeosophageal echocardiography and angiography showed a highly mobile and tubular structure shifting within the valve. We went for a surgical extraction via sternotomy on cardiopulmonary bypass (CPB). A 6cm longish intimal cylinder was hassle-free extracted. 4 days postoperatively the left sided radial pulse was missing. In a subsequent computed tomography angiography (CTA) scan a proximal dissection as well as an intimal flap, causing a subtotal stenosis of the left subclavian artery, was detected. Consecutively the intimal cylinder was removed using a Fogarty-balloon. Pre-discharge control revealed recurrence of peripheral radial pulse and an unimpeded function of the TAVI prosthesis. The patient presented no sequela at discharge.
Conclusion: Though TAVI is a well-advanced technique complications are not completely avertable. Therefore, it is advisable to have recourse to cardiac surgery.
Study of the Relationship between Malignant Pleural Effusion and
Common Causing Tumors
Authors: Juha Kinda , Al-bardan Hossam
Published: October 2022

Introduction:
Malignant pleural effusion is one of the most important causes of pleural effusion. It can sometimes be difficult to diagnose a malignant effusion due to the uncertainties of biopsy determination of a pleural result. The aim of this study was to evaluate the clinical features of malignant pleural effusion.
Methods:
A retrospective study on patients with malignant pleural effusion at Al-Mujtahid Hospital and Ibn Al-Nafis from December 2021 to June 2022.
Results:
Of the 188 patients, admitted with a story, 40.4% were adult patients, adults, adults, adults, and girls. The mean age of the patients was 56 years. Mount infected by 51.1%. And 12.8% had the right-sided patients with 57.4%, and the left-sided patients had the disease. Tumor effusions were treated 63%, pleurisy 13%, and chest blasting 24.1%. Effusion analysis of 91.5% exudate pattern, 8.5% transudate pattern, presence of malignant cells at 10.6%. The demographic dialogue of patients and adjacent factors was associated with both effusion and primary tumor. (P < 0.05).
Conclusion:
The results of this study indicate that there are issues related to pleural effusion. Programs should aim at using modern methods of diagnosing and treating malignant pleural effusion as it has an important role in determining the prognosis.
Digitalization and the Covid-19-led public crisis management: an evaluation of financial sustainability in the Azerbaijan business sector
Authors: Gurbanov Nijat , Yagublu Nargiz , Akbarli Narmin , Niftiyev Ibrahim
Published: October 2022

One of the key challenges for businesses during the Covid-19 pandemic has been to maintain financial sustainability despite the public crisis and consumer demand shocks. While some companies have managed to digitize and cope with the new realities, others have not. This will determine the future of companies and the direction of anti-crisis tools in management strategies. The purpose of this study is to analyze the use of digitalization as an anti-crisis tool among Azerbaijani businesses during the Covid-19 outbreak. The data set is based on voluntary survey data gathered from key businesses of the Azerbaijan economy. Our analysis applied k-means clustering, the related-samples Wilcoxon Signed Rank test and the independent-samples Mann-Whitney U test to learn whether there was any connection between digitalization and financial sustainability. Our findings indicate that 42% of the businesses that participated in the study obtained benefits by using digitalization as a crisis management tool during the Covid-19 pandemic period, but 38% of the respondents did not report any significant changes in their businesses despite increased digitalization efforts. Moreover, 20% of the businesses examined experienced negative changes after digitalization. The results of the independent-samples Mann-Whitney U test indicated that those businesses that had high scores before and after the increased digitalization efforts during the Covid-19 pandemic, achieved higher median profits, while the businesses with lower scores experienced a financial loss. As can be seen from the results, the chances of benefiting from digitalization are rather uncertain for local businesses. The main policy conclusion from this study is that businesses in Azerbaijan need to address the digitization challenge comprehensively to increase benefits and reduce costs. The results of our study are useful for business owners, policy makers, and top managers when developing strategies for enterprise-level digitization, especially during and after viral outbreaks.
A new approach to evaluate the index of ISO 9001
Authors: Ceko Enriko
Published: October 2022

The purpose of this study was to offer a new approach to evaluate the index of ISO 9001 standard, as so far countries are listed for the ISO 9001 standard based only on the number of ISO 9001 certificates issued for each country, and this perception does not correspond to reality, because some countries that are listed per alphabetic order on top, doesn’t enjoy the property of having a better ranking when it comes to rank countries per number of ISO 9001 certificates issues, or when it comes to rank countries about their weight on the issue. On the other side, listing countries simply by the number of ISO 9001 certificates issued, doesn’t reflect the real weight of countries on the issue, because this rank should be adjusted with the number of businesses of countries taken into consideration, better understanding of ranking models used. A new approach to ranking countries about this issue is needed, reflecting the issue of taking into consideration the number of ISO 9001 certificates issued in a country per number of businesses in that country, as a better way of evaluating the index of ISO 9001 standard. The methodology/method used to conduct this study were (1) the data collection on the number of ISO 9001 certificates issued per country, (2) the data collection on the number of businesses in each country, (3) the division of the number of ISO 9001 certificates issued with the number of businesses, (4) construction of a new ranking list of countries based on the ISO 9001 standard index, (5) inversing the list to give the right value/rank of countries, and graphics draw of the new approach for better visualization and understanding the issue. The main conclusion of this study is that a new approach is needed to evaluate the index of ISO 9001 standard as a more appropriate indicator for listing/ranking countries and this serves all those interested in the academic field, public administration, and the reports and studies of the national and international level of organizations, to create a better perception of doing business in general and on the aspects of quality management in particular, especially when it comes to making the most appropriate comparisons between countries on these issues, weighting them numerically and graphically, as well as helps on understanding, and for a better approaching of socio and economic issues related to ISO standards and continuous improvement of people and organizations.
Ação educativa em saúde: a prática da higienização auditiva correta
Authors: FERREIRA Laura Garcia Queiroz , GUIMARÃES Lara Rezende , COSTA Nilson Junio Faustino da , PACHECO Geovanna Alves , BORGES Ingrid Fernandes , TADOKORO Kaienne Basílio da Silva , SILVA Cesar Augusto Cirino , PEREIRA Bruna Tavares , MARTINS João Alexandre Ferreira , CIPRIANO Phamela Aparecida
Published: October 2022

A saúde auditiva abrange, em um dos aspectos, a prática da higienização correta do canal auricular, a fim de prevenir doenças inflamatórias e infecciosas, como a Otite Externa. Este trabalho trata-se de um relato de experiência, realizado com base nas percepções dos autores, acerca da preparação e da aplicação da atividade educativa em saúde proposta pela disciplina de PROINTER II, do curso de Enfermagem da Universidade Federal de Uberlândia (UFU). Diante da importância da audição e da qualidade de vida dos cidadãos, este trabalho tem como propósito difundir o conhecimento acerca da temática, bem como preparar os autores para troca de saberes com a comunidade. Para a análise subjetiva dos efeitos advindos da ação, todos os participantes demonstraram as perspectivas positivas e negativas a partir de uma nuvem de palavras. O companheirismo, o orgulho, a dispersão do saber, o trabalho em grupo e o conhecimento são apresentados pelos membros como descritores positivos para a ação. Entretanto, a ansiedade, o pouco tempo de desenvolvimento, a vergonha, a timidez e os gastos surgiram como dificuldades para o estabelecimento da ação, mas não impediram o sucesso do trabalho no ambulatório. Portanto, essa ação educativa possibilitou uma experiência proveitosa tanto para o público quanto para os estudantes, responsáveis pela execução da atividade. Os discentes atuaram na promoção em saúde, esclarecendo dúvidas e instruindo os participantes acerca da correta higienização auricular a partir do uso de um molde de orelha, de um banner e de perguntas ao público, bem como utilizando dados retirados de artigos científicos, a fim de difundir informações seguras e confiáveis aos pacientes da otorrinolaringologia.
Radiation situation in the territory of the uranium legacy site in the Bambakai Valley (Transbaikal Territory)
Authors: Titov A. V. , Shandala N. K. , Belskikh Yu. S. , Seregin V. A. , Doroneva T. A. , Filonova A. A. , Semenova M. P. , Gushchina Yu. V. , Pavlenko-Mikhaylov Yu. N.
Published: October 2022

The article presents the results of a study of the current radiation situation at the uranium legacy site located in the territory of the Bambakai Valley (Transbaikal Territory), formed in the period from 1973 to 1989 due to the discharge of mine water. During the radiation survey, the method of pedestrian gamma survey was used to measure the ambient dose equivalent rate. Soil sampling was carried out to study the radionuclide specific activities in the soil. The activity of gamma-emitting radionuclides in the samples was measured with a stationary gamma spectrometer. The activities of 210Po and 210Pb were measured after their radiochemical extraction from samples. It was found that the values of ambient dose equivalent rate in the territory of the valley varied over the wide range from 0.1 to 1.4 µSv/h in the areas under manmade contamination. The estimated average value of the gamma background for this place is 0.14±0.02 µSv/h. The specific activities of 238U, 226Ra, 235U, 210Pb and 210Po in the surface 10-cm soil layer at the site are from 10-40 times higher than the background values. The most part of radionuclides in the soil is in the acid-soluble form. Effective doses of the workers involved in hay harvesting in the area of the fallow land do not exceed 1.5 µSv/year. Doses of terrestrial environmental media (grass, earthworms) are 100 and more times lower than the safe level of exposure to biota.
Performance assessment of the operational management of urban drainage systems: a case study of Bejaia City, Algeria
Authors: Igroufa Meriem , Benzerra Abbas , Seghir Abdelghani , Merah Ferhat , Bedjou Abdelhamid
Published: October 2022

Over the recent years, managers of the Algerian National Sanitation Office (ONA) have been worrying about the degraded state of their Urban Drainage Systems (UDS). This infrastructure failure is due essentially to the lack of funding and absence of adequate structured methodology for diagnosis and maintenance. As a result, ONA's managers found it very interesting to get a tool that allows them to assess their management of UDS operation. The aim of this paper is therefore to provide an assessment tool to managers for a good network operation. The adopted approach is participative and takes into account the specific local context. Six performance indicators, grouped into two criteria, have been constructed to achieve this objective. These indicators have been chosen for their effectiveness; they are scaled to get their performance scores according to a scaling constructed here based on standards when available and to the ONA expert's recommendations. The developed tool is applied to the UDS of Bejaia City, in north-eastern Algeria. The assessment and the analysis of the performance evolution of these indicators for the period 2017–2021 are carried out. The results highlighted successes that can be maintained as well as weaknesses that need to be improved.
The modification of biomass waste by cerium-based MOFs for efficient phosphate removal: excellent performance and reaction mechanism
Authors: He Jiaojie , Yang Yixing , Qu Min , Yang Yue , Yang Liwei
Published: October 2022

Due to the possibility of causing eutrophication, excessive phosphate discharged into water bodies always threatens the stabilization of aquatic ecosystem. A promising strategy is to remove phosphate from water by the utilization of biomass waste as adsorbents. In this paper, the corn straw (CS) and pine sawdust (PS) are chosen for adsorption; however, the phosphate removal capacities of them are very limited. Considering the high phosphate uptake of trivalent cerium, Ce (III)-based nanoparticles (CD and CT) are selected to be loaded on the biomass by hydrothermal synthesis to obtain four modified materials. CD is metal organic frameworks (MOFs) with Ce5(BDC)7.5(DMF)4 as its molecular structure, while CT is MOFs derivatives with [Ce (HCOO)]n as its crystal structure. The adsorption capacities of CS-CD, PS-CD, CS-CT and PS-CT reach 181.38, 183.27, 225.55 and 186.23 mg/g. But on account of the different molecular structures, CS-CD and PS-CD achieve great phosphate uptake under wide applicable scope of pH from 2 to 11, whereas CS-CT and PS-CT only under acidic conditions. The analysis of the adsorption mechanism indicates that due to the unsaturated coordination bond of CD, it could remove phosphate through coprecipitation and ion exchange even under alkaline conditions.
Ayak Bilek-Brakial İndeksi‘nin glisemik düzey, diyabet komplikasyonları ve oksidatif stres indeksi ile ilişkisi
Authors: BOYACI İhsan
Published: October 2022

Amaç: Ayak Bilek-Brakial İndeksi (ABİ), periferik arter hastalığını taramak ve kardiyovasküler prognozu değerlendirmek için kullanılan bir yöntemdir. Bu çalışmanın amacı, tip 2 diyabet (T2D) hastalarında ABİ’nin glisemik düzey, biyokimyasal parametreler, mikro-makrovasküler komplikasyonlar ve oksidatif stres indeksi (OSİ) ile olan ilişkisini incelemek ve iskemi için risk oluşturabilecek faktörleri belirlemektir.Yöntemler: Kesitsel retrospektif olarak tasarlanan çalışmaya 153 kişi dâhil edildi. Katılımcılar, sağlıklı kontrol, prediyabet ve manifest T2D olarak glisemik düzeylerine göre ayrıldı. Ayrıca ABİ’ye göre de gruplandırılan katılımcıların, ABİ ve karotis arter incelemeleri, radyolog tarafından doppler ultrasonografi ile yapıldı. Diyabetik nöropati ve retinopati teşhis muayeneleri nörolog ve oftalmolog tarafından gerçekleştirildi. Antropoemetrik ölçümler, OSİ ve biokimyasal paramatreler tüm gruplar için çalışıldı.Bulgular: Gruplar arasında ABİ düzeylerine göre yaş ve diyabet süresi açısından anlamlı fark vardı (p<0.05, p<0.001). ABİ iskemi düzeyi ile glisemik düzey arasında önemli ölçüde farklılık bulundu. ABİ grupları arasında, açlık kan glukozu, tokluk kan glukozu, insülin direnci, kreatinin ve albüminüri seviyeleri anlamlı şekilde farklıydı. Benzer şekilde ABİ iskemik grubu ile makrovasküler komplikasyonlar arasında da anlamlı fark gözlendi (p<0.001). Makrovasküler komplikasyon grupları ile ABİ, OSİ ve hemoglobin A1c (HbA1c) arasında anlamlı fark saptandı (p<0.001). Karotis doppler incelemesine göre 6 gruba ayrılmış kohort ile OSİ arasında anlamlı bir fark bulundu (p<0.05). Diğer yandan, mikrovasküler komplikasyon grupları ile HbA1c ve OSİ arasında dikkate değer bir değişiklik vardı (p<0.001, p<0.05). İskemi için risk oluşturabilecek faktörler diyabet süresi, açlık insülin düzeyi, tokluk kan glukozu ve insülin direnci olarak belirlendi. Modelin genel doğruluğu %68.6 olarak hesaplandı.Sonuç: T2D’de periferik arter hastalığı taraması için belirli bir yaşı beklemek yerine diyabetin süresi dikkate alınabilir ve tarama buna göre öne çekilebilir. Diyabet süresi, açlık insülin düzeyi, tokluk kan glukozu ve insülin direnci iskemi için risk faktörleri olarak gösterilebilir.
Stereoscopic Differences in the Identification, Bioactivity, and Metabolism
of C-20 and C-24 Epimeric Ginseng Saponins
Authors: Zhang Juan , Zhao Ruolin , Hou Guige , Wang Qibao , Zhao Fenglan , Liu Zhi , Meng Qingguo
Published: October 2022

Ginseng, the roots and/or rhizomes of Panax spp.(Araliaceae), has been used as a popular, herbal medicine in East Asia for at least two millennia. As a functional food and health-enhancing supplement, ginseng has been shown to have a wide range of pharmacological effects on cognition and blood circulation as well as antioxidant, antitumor, and anti-fatigue effects. The main active properties of ginseng are considered to be the triterpene saponins, often referred to as ginsenosides, which are the basis for their wide-ranging of pharmacological effects. Four of these glycosides, including protopanaxadiol, protopanaxatriol, ocotillol, and oleanolic acid, are the most common saponins found in ginseng. Compared to other ginsenosides, the C-20 chimeric ginsenosides, including Rg3, Rh2, Rg2, Rh1, PF11, C-20, and C-24, as well as epimeric ocotillol-type saponins and their derivatives exhibit significant, steric differences in biological activity and metabolism. 20(R)-ginseng saponins, one class of important rare ginsenosides, have antitumor, antioxidative, antifatigue, neuroprotective and osteoclastogenesis inhibitory effects. However, 20(R)-ginsenosides are rare in natural products and are usually prepared from 20(S)-isomers through chemical differential isomerization and microbial transformation. The C20 configuration of 20(R)-ginseng saponins is usually determined by 13C NMR and X-ray single-crystal diffraction. There are regular differences in the chemical shift values of some of the carbons of the 20(S)- and 20(R)-epimers, including C-17, C-21, and C-22. Owing to their chemical structure and pharmacological and stereoselective properties, 20(R)-ginseng saponins have attracted a great deal of attention in recent years. Herein, the stereoscopic differences in the identification, bioactivity, and metabolism of C-20 and C-24 epimeric ginseng saponins are summarized.
Stem Cell and Oxidative Stress-Inflammation Cycle
Authors: Buzoglu Hatice Dogan , Burus Ayse , Bayazıt Yasemin , Goldberg Michel
Published: October 2022

:

Under a variety of physical and experimental settings, stem cells are able to self-renew and
differentiate into specialized adult cells. MSCs (mesenchymal stromal/stem cells) are multipotent stem
cells present in a wide range of fetal, embryonic, and adult tissues. They are the progenitors of a variety of
specialized cells and are considered crucial tools in tissue engineering. MSCs, derived from various tissues,
including cord blood, placenta, bone marrow, and dental tissues, have been extensively examined in
tissue repair, immune modulation, etc. Increasing the vitality of MSCs and restoring cellular mechanisms
are important factors in treatment success.

:

Oxidative stress harms cellular molecules such as DNA, proteins, and lipids due to the overproduction of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) in cells and tissues or insufficiency of
antioxidant systems that can inactivate them. Oxidative stress has a close link with inflammation as a
pathophysiological process. ROS can mediate the expression of proinflammatory genes via intracellular
signaling pathways and initiate the chronic inflammatory state. At the same time, inflammatory cells secrete
a large number of reactive species that cause increased oxidative stress at sites of inflammation. In
inflammatory diseases, the differentiation of stem cells and the regenerative and wound healing process
can be affected differently by the increase of oxidative stress.

:

Recent studies have indicated that dental pulp stem cells (DPSCs), as a resource of adult stem cells, are an
attractive option for cell therapy in diseases such as neurological diseases, diabetes, cardiological diseases,
etc., as well as its treatment potential in pulp inflammation. The future of oxidative stressinflammation
cycle and/or ageing therapies involves the selective elimination of senescent cells, also
known as senolysis, which prevents various age-related diseases. Most pathologies are implicated on the
effects of ageing without exerting undesirable side effects.
The Growth-promoting and Antipathogenic Effects of Microorganisms Isolated from Solanum nigrum L. and Inoculated in Solanum lycopersicum L.
Authors: Borodai Vira V. , Kolomiiets Yuliia V. , Likhanov Artur F. , Zelena Liubov B. , Butsenko Lyudmyla M. , Shemetun Kateryna I. , Churilov Andrii M. , Blume Yaroslav B.
Published: October 2022

Background:

In recent years, there has been a growing scientific interest in the biodiversity and function of endophytic bacteria, as well as the prospects for their practical use.

Objective:

The purpose of this work was to isolate endophytic microorganisms from generative organs of the European black nightshade (Solanum nigrumL.), assess their biological activity, and test their growth-promoting/protective effects in tomato (Solanum lycopersicumL.) plants.

Methods:

From the tissues of generative organs ofS. nigrumplants, 14 strains of endophytic microorganisms were isolated. Most of them belonged toBacillussp. The physiological and biochemical properties and enzymatic and oxidative metabolism of some of them were studied. Sequence analysis of 16S rRNA fragments revealed 99,65% similarity of BA1s-OSN-0820 and BAXS-OSN-0820 isolates toB. amyloliquefaciensstrains, while the ITS sequence of the RHC-OSN-0820 isolate showed 99,65% of similarity toRhodotorula kratochvilovae.

Results:

The actions of these endophytes against tomato pathogenic bacteria and fungi were then tested. The isolates had a significant bacteriostatic effect againstXanthomonas campestris,the causative agent of black bacterial spotting of leaf, andClavibacter michiganensis,the causative agent of bacterial wilt, with a lower effect againstPseudomonas syringae,the causative agent of bacterial spotting. Isolates also showed selectivity against micromycetes that cause mycosis in tomatoes grown indoors, such asFusarium oxysporum, Alternaria solani, Botrytis cinerea, Sclerotinia sclerotiorum,andF. acuminatum. In particular, the highest antifungal activity was detected againstS. sclerotiorumand fungi of theFusariumgenus. Inoculation of tomatoes with endophytic microorganisms revealed a positive effect on seed germination efficiency and the stimulation of seedling growth. Thus, the effectiveness of interspecific transfer of endophytic microorganisms from a wild,S. nigrum,to a cultivatedSolanumspecies,S. lycopersicum,was reported.

Conclusion:

A consortium of plant-associated microorganisms isolated from a wild relative has a positive effect on the germination of tomato seeds, stimulating the formation of the root system and nutrition of seedlings. The antagonism of the isolates against phytopathogenic fungi and bacteria provides long-term protection during the most critical stages of plant development and has prospects for the development of microbial biologics for cultivated plants of the Solanaceae family.
Pectin/Pectin Derivatives as Potential Scaffolds for the Tissue Engineering
Applications
Authors: Pandey Akanksha , Sharma Pramod Kumar , Malviya Rishabha , Rahate Kalpana
Published: October 2022

Pectins are polysaccharides that have a sequence that is similar to that of plant cell membranes
that are predominantly made up of galacturonic acid units, and their concentration, morphology,
and molecular mass vary. Tissue engineering is a multidisciplinary field that examines natural
replacement for the injured tissue to heal or preserve its function, and it involves using scaffolds, cells,
and biomolecules. Biocompatible, biodegradable, and permeable scaffolds are required. The study
aims to find the potential of pectin/pectin derivative scaffolds for tissue engineering applications.
Short-term Power Load Forecasting Based on Orthogonal PCA-LPP
Dimension Reduction and IGWO-BiLSTM
Authors: Wang Yahui , Yi Lingzhi , Zhu Jiang , Liu Jiangyong , Wang Shitong , Liu Bo
Published: October 2022

Background:

Accurate power load forecasting is of great significance in ensuring power load planning, reliability and economic operation. The traditional power load is easy to be affected by climate, environment, date type and other factors, resulting in the problem of poor forecasting accuracy. Therefore, it is necessary to study power load forecasting.

Objective:

Through machine learning, dimension reduction method and intelligent optimization algorithm, the accuracy of load forecasting is improved

Methods:

In order to fully extract load information and improve the accuracy of short-term load forecasting for campus electricity, an improved combination of orthogonal dimensionality reduction and Bilstm is proposed to optimize the hyperparameters in BiLSTM using an improved gray wolf algorithm. Firstly, using the advantages of principal component analysis (PCA) and Locality Preserving Projection (LPP) to maintain the global and local structure of the data, respectively, the Orthogonal PCA-LPP（OPCA-LPP） dimensionality reduction method is proposed to reduce the dimensionality of the original multidimensional data. Finally, the dimensionality-reduced data is used as the input of BiLSTM and optimized by the improved Gray Wolf algorithm, which can enhance the prediction capability of the model and thus achieve accurate prediction of short-term electric load.

Results:

The Mae and RMSE of this paper are 1.6585 and 1.7602 respectively. The results show that the method proposed in this paper is reasonable

Conclusion:

This method is applied to power load forecasting. The comparative experimental results show that this method reduces the dimension of data input, simplifies the complexity of network input data, and improves the accuracy of load forecasting. Compared with other methods, it can effectively improve the accuracy of load forecasting, and provide a basis for formulating reasonable power grid operation mode and balanced dispatching of power grid.
Contents of Lee Dong-yoon's writings and an overview of poetry
Authors:   The Association of DaeDong-Hanmun, Lee Jae-sook
Published: October 2022

Minjae Lee Dong-yoon(1727~1809) is a writer of ≪Baksochonhwa≫. After he was introduced to the academic world, research has been accumulated, but there is still lack of research on his life, thoughts, and literature. By introducing Lee Dong-yoon’s collection of works, ≪Minjaeyugo≫, this study is aimed to examine the aspects of him as a writer found in his life, works, and Chinese poems and figure out his pursuit in literature.
The three books of ≪Minjaeyugo≫ that have been handed down up to now are unfinished manuscripts of which order is not decided. It contains 631 themes and 1,276 works of Chinese poetry written by him from 1757 when he was 30 years old to his later years. About the contents, it includes 49 Seo(書), 3 Seo(序), 3 Gi(記), 17 Jebal(題跋), 45 Jemun(祭文), 7 Gomun(告文), 6 Haengjang(行狀), 8 Haengrok(行錄), 2 Eonhaengrok, 4 Yusa(遺事), 8 Myoji(墓誌), and 25 Japjeo(雜著).
This study outlines Lee Dong-yoon’s works of Chinese poetry as 1) the records of daily life grounded on Cheonghan(淸寒) and affection, 2) the life of Anbunjijok (安分知足) and intention for Seonghak(聖學), and 3) preference for creating Old poems written at full length and Chinese poems written in series. First, although Lee Dong-yoon had the reputation of the royal Jeonju Lee’s family, he was in distress through his life for poverty and destitution. Taking ordinary and plain things in everyday life as the themes of his Chinese poems, he pursued simplicity about all sorts of feelings in the world. This is in line with the meaning of ‘Bakso(樸素)’ taken from ≪Jangja(莊子)≫. Second, as an old man in the rural area of the Chungcheong Province, Lee Dong-yoon was immersed into Gyeonghak(經學), solidified his will for Studies for oneself, learning to develop and cultivate oneself, and pursued the life of Anbunjijok(安分知足) by writing Chinese poems. Third, Lee Dong-yoon’s Chinese poems were intensively created in his later years, and concerning the forms, Jangpyeongosi and Yeonjaksi formed a large part. In the Hoseo area, he interacted with Namdang’s disciples and the brothers of Andong Kim’s family deeply, and it seems that this influenced him when he wrote Jangpyeongosi in the 18th century.
Lee Dong-yoon learned from Namdang Han Won-jin and Byeonggye Yoon Bong-gu and was greatly influenced by Yoogeundang Kim Gyo-haeng. In fact, ≪Minjaeyugo≫ contains a large number of writings related to that. There are many notable works such as memoirs about his wife and sisters or about Sir Yoogeundang, and this author expects that in-depth studies will be carried out about Lee Dong-yoon’s literature and thoughts afterwards.
Uniqueness of "us" created by physical education
Authors: Ishigaki Kenji
Published: October 2022

The concept of intercorporeality refers to a fundamental function of an individual’s body that enables them to be or feel interconnected with other human beings. Researchers at the Department of Sport and Health Science, Tokai Gakuen University, Japan, led by Professor Kenji Ishigaki
are exploring whether intercorporeality can help inform the physical education, play and sports included in the school curriculum. They hope that by encouraging ‘corporeal feeling’ towards others, children can gain a better sense of morality and belonging. This, in turn, can improve
mental health and engagement with physical education. Ishigaki believes that the intercorporeal approach will reveal what kind of exercise play will contribute to the development of children’s morality or what kind of ‘corporeal feeling’ is important for the children’s
body. The expectation is that philosophical analysis of these ‘corporeal feelings’ will shed light on the types of exercise, play and sports that should be arranged and incorporated into the Japanese school curriculum. An important idea for Ishigaki and the team is that when we
think in the same way as others do about a particular thing, an intersubjective ‘we’ is established but in practising physical education and exercise in sports, a different kind of ‘we’ is established. This is the the intercorporeal ‘we’ as corporeal feeling
that is unknowingly generated in the dimension of the human body,’
Social contribution movement by the American Christian Evangelicals: addressing poverty
Authors: Horiuchi Kazunobu
Published: October 2022

Politics and religion are closely related. Professor Kazunobu Horiuchi, Reitaku University, Japan, is interested in the relationship between evangelicals and politics in the US and believes there are misconceptions about conservative evangelicals. He is knowledgeable about the involvement
and influence of conservative evangelicals in politics and is also interested in the links between religion and poverty. Indeed, in recent years, Horiuchi has been focusing on his research on evangelical efforts to address poverty issues, including conservative evangelicals’ reluctance
to contribute to societal issues such as eradicating poverty and the active role of the Evangelical Left in such societal issues. In one study, he is working to empirically verify how conservative evangelical and liberal Evangelical Left churches actually tackle social or international poverty
issues in church-side social contribution activities centred on poverty issues. To do this, he is exploring the history of the formation of the Religious Left and the Evangelical Left, the contents of the movement and an examination of the possible impact of these movements on the future of
US society and politics. Horiuchi now has a grant to conduct research on the relationship between the US evangelical movement and race issues and this will be an area of focus for the next three years.
The path to gender equality in R&I
Authors: Annette Lucy
Published: October 2022

There is a well documented gender gap in science and technology and, despite advancements, women remain underrepresented, particularly in fields such as engineering, mathematics, computing and physics. This is worsened still by the presence of skills shortages in these fields and UNESCO
recommends efforts to attract and retain women to these fields. The European Commission (EC)’s European Research Area (ERA) Policy Agenda intends to ‘promote gender equality and foster inclusiveness’. ‘She Figures’ is a study that began in 2003 and collects data
and statistics on the status of gender equality in European research and innovation (R&I). It is updated every three years, allowing progress with the evolving situation to be closely monitored. In the 2021 edition of ‘She Figures’ it is highlighted that while numbers of female
students at bachelor’s, master’s and doctoral levels are steadily rising, women are distinctly underrepresented in R&I careers. Mariya Gabriel, Commissioner for Innovation, Research, Culture, Education and Youth, said: “We still need to do more to promote gender equality,
in particular to inspire girls for a career in STEM.” The report highlighted disparities among different fields of study with, for example, only 21 per cent of female ICT graduates and 27 per cent of female engineering graduates, while in health and welfare, the figures rise to 60 per
cent and 67 per cent respectively. This suggests remaining outdated misconceptions in terms of traditionally male-dominated and female-dominated areas and the need for change.
Developing and Implementing the “Unknowing-Oriented Teaching Model” in teacher training programs ‐ the concept of ignorance-based instruction
Authors: Tzeng Jeng-Yi
Published: October 2022

Learning is a key fundamental of life. Professor Jeng-Yi Tzeng, Institute of Learning Sciences and Technologies, National Tsing Hua University, Taiwan, has been investigating the differences between knowledge-based and ignorance-based pedagogy. He believes it is important to recognise
the importance of seeking non-knowledge (learning to be ignorant) alongside the pursuit of knowledge (learning to know). Most institutions follow a knowledge-based learning approach that prizes knowledge over non-knowledge but Tzeng believes different learning techniques could help students
and teachers alike. He believes the learning journey should include a focus on ignorance, with exploration of the gaps that received knowledge doesn’t cover. Tzeng has studied different paradigms used in pedagogy such as the paradigm of ignorance, which poses ignorance as the focus for
meaning and organises learning and the popular paradigm of epistemology, which builds on introducing new knowledge by building on existing knowledge. He has been developing and implementing the “unknowing-oriented teaching model” in the teacher training programmes run at the Centre
for Teacher Education with heavy involvement from students, including encouraging students to ask good quality questions to be used in discussion in class. The response from students so far has been profoundly positive and the model has enabled them to develop more critical thinking skills.
Having focused on the teaching side of things, Tzeng is now exploring ignorance-based learning.
Perovskite Solar Cells: Assessment of the Materials, Efficiency, and Stability
Authors: Boro Binita , Porwal Shivam , Kumar Dinesh , Mishra Snehangshu , Ghosh Subrata , Kansal Sakshi , Chandra Amreesh , Singh Trilok
Published: October 2022

Solar cells based on organic-inorganic lead halide perovskites are popular in the photovoltaic community due to their high efficiency, low cost, and solution processability. Understanding the fundamentals of metal halide perovskite and its interfaces is extremely important for achieving high-quality materials and developing efficient devices using these materials with the necessary properties. Various methodologies have been used to evaluate the excellent optoelectronic properties, efficiency, and stability of PSCs. In this article, we reviewed the case studies of characterization techniques to investigate structural, optical, and electrical properties of perovskite material via electron microscopic techniques (SEM and TEM), J-V measurements, AFM, XRD, and spectroscopy techniques (PL, UV-vis, XPS, Raman, FTIR, and EIS). PSCs also need to have long-term stability and large-scale applicability for successful commercialization. In this review, we studied perovskite in detail to understand the key properties of the materials to facilitate the commercialization of PSCs.
Perspectives to Modify and Counter Aging in the Frame of Subtelomere–Telomere Theory of Aging
Authors: Libertini Giacinto
Published: October 2022

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The subtelomere–telomere theory of aging offers what is required by the interpretation of aging as a programmed phenomenon. The experimentally documented mechanisms that are part of the subtelomere–telomere theory are the repression of subtelomeric sequences (TERRA sequences) consequent to the sliding of a telomeric hood over subtelomere in proportion to telomere shortening, epigenetic modifications caused by the repression of the subtelomeric sequences, cell senescence and gradual cell senescence (which are not synonyms, as discussed in the text), progressive decline of stem cells, and effects of these phenomena over the whole organism. Evidence against the interpretation of cell senescence and telomerase restrictions as defense mechanisms against cancer is reported. Consequently, the fears that telomerase activation or senescent cell elimination are potentially oncogenic factors should be eliminated as preconceived ideas or limited on the basis of any available evidence. In the context of the mechanisms described under the subtelomere–telomere theory, three types of strategies that could be used to modify and counter the mechanisms of aging can be deduced, namely telomerase activation, senescent cell elimination, and restoration of stem cell numbers to that existing in young individuals. The limits and the potential effectiveness of these methods, already the subject of active research, are briefly discussed.
Drug and Substance Abuse Point of Interest (POI) Conflation and Spatial Attribute Enrichment Framework (Preprint)
Authors: Kelani Zeyad , Emish Mohamed , Young Sean
Published: October 2022

BACKGROUND

Point of Interest (POI) data (e.g., the locations where people are visiting based on their mobile device movement and self-reports) is increasingly being studied in spatial analysis of pressing healthcare issues, such as for assisting with substance use prevention and treatment. However, the task of retrieving accurate healthcare POI information remains complicated, in part, due to the lack of available POI data except from proprietary sources. With the abundance of open-source projects and commercial geographical databases, POI conflation may be a useful method to enrich spatial data attributes and coverage by merging POI records from different sources.

OBJECTIVE

This study outlines a proposed framework for healthcare POI conflation and spatial enrichment that involves a multi-step process.

METHODS

This framework includes the following steps: POI data collection from Open-source Location-Based Services (OLBS), geographic and spatial attributes collection, calculating similarity across datasets, POI matching, spatial attributes enrichment, manual labeling, Quality Control (QC), and a deployable enriched database. We tested the viability of our proposed framework on a drug and substance abuse use case in California, USA.

RESULTS

Based on our findings, our automated approach was able to detect 11,936 unique POIs related to this healthcare tag. Using a proprietary commercial dataset, we found that 38% of their healthcare POIs were substance use-related POI’s (n = 104 number of substance abuse POIs from SafeGraph). In contrast, our framework, which included a much larger number of healthcare POI’s due to our conflation matrix, was composed of 33% substance use-related POI’s (n = 559 number of POIs).

CONCLUSIONS

We conclude that using our proposed framework can provide a larger number of POIs with similar relevance and spatial attributes as proprietary commercial datasets, allowing this method to be low-cost method for studying substance use-related POIs.