bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance of five dynamic models in predicting tuberculosis incidence in three prisons in Thailand
Authors: Mahawan Nithinan , Rattananupong Thanapoom , Sri-Uam Puchong , Jiamjarasrangsi Wiroj
Published: January 2025

This study examined the ability of the following five dynamic models for predicting pulmonary tuberculosis (PTB) incidence in a prison setting: the Wells–Riley equation, two Rudnick & Milton-proposed models based on air changes per hour and liters per second per person, the Issarow et al. model, and the applied susceptible-exposed-infected-recovered (SEIR) tuberculosis (TB) transmission model. This 1-year prospective cohort study employed 985 cells from three Thai prisons (one prison with 652 cells as the in-sample, and two prisons with 333 cells as the out-of-sample). The baseline risk of TB transmission for each cell was assessed using the five dynamic models, and the future PTB incidence was calculated as the number of new PTB cases per cell and the number of new PTB cases per 1,000 person-years (incidence rate). The performance of the dynamic models was assessed by a four-step standard assessment procedure (including model specification tests, in-sample model fitting, internal validation, and external validation) based on the Negative Binomial Regression model. A 1% increase in baseline TB transmission probability was associated with a 3%–7% increase in future PTB incidence rate, depending on the dynamic model. The Wells–Riley model exhibited the best performance in terms of both internal and external validity. Poor goodness-of-fit was observed in all dynamic models (chi-squared goodness-of-fit tests of 70.75–305.1, 8 degrees of freedom, p < .001). In conclusion, the Wells–Riley model was the most appropriate dynamic model, especially for large-scale investigations, due to its fewer parameter requirements. Further research is needed to confirm our findings and gather more data to improve these dynamic models.
The ionic liquid-assisted sample preparation method pTRUST allows sensitive proteome characterization of a variety of bacterial endospores to aid in the search for protein biomarkers
Authors: Taoka Masato , Kuwana Ritsuko , Murakami Yoshinari , Kashima Akiko , Nobe Yuko , Uekita Takamasa , Takamatsu Hiromu , Ichimura Tohru
Published: January 2025

Bacterial endospores are ubiquitous and are responsible for various human infections. Recently, we reported that an ionic liquid (IL)-based sample preparation method (named pTRUST) facilitated highly efficient shotgun analysis of the Bacillus subtilis spore proteome in trace samples. In this study, we evaluated the efficiency and applicability of the pTRUST technology using three different spore preparations: one purified from the closely related subspecies B. subtilis natto and two from B. licheniformis and B. cereus. We showed that the pTRUST method allowed rapid solubilization and processing of all tested spore samples prepared for highly sensitive mass spectrometry (MS) analysis. Bioinformatics analysis using the BLAST program suggested that a set of 25 proteins commonly identified between the above three species and B. subtilis spores may be universal biomarkers among various bacterial species, including 43 spore-producing bacteria associated with industrial dairy processing environments and product spoilage. In contrast, the two identified proteins, D4FV94 in B. subtilis natto and Q737A2 in B. cereus, are likely species-specific biomarkers, because their orthologs are absent or rare in all organisms. The sensitivity and applicability of pTRUST, along with the putative protein biomarkers identified in this study, will facilitate a wide spectrum of spore research for biological and clinical applications.
Knowledge, attitudes, and practices (KAP) of animal health staff and farmers towards brucellosis control in sheep and goat in China: A cross-sectional study
Authors: Xu Quangang , Amonsin Alongkorn , Jeamsripong Saharuetai
Published: January 2025

Background

In China, brucellosis has resurfaced recently with a discernible spatial distribution, particularly affecting dairy herds and small ruminant populations. However, limited dissemination of knowledge, attitudes, and practices (KAP) for brucellosis control exists among farmers and animal health staff. This study aimed to assess the KAP of brucellosis control and prevention in animal health staff and farmers, with the goal of educating the public regarding the application of efficient brucellosis control and prevention strategies.

Methods

We conducted a cross-sectional survey involving 1,468 participants, comprising farmers (n = 1,067) and animal health staff (n = 401) based on their significant density of sheep and goat population. They completed a questionnaire targeting a specific group of farmers and animal health staff through face-to-face interviews. The KAP scores were then categorized as either satisfactory or unsatisfactory based on a cutoff set at ≥80% of the total score for satisfactory. Binary logistic regression was used to identify the association between KAP and geographical information.

Results

The results indicated satisfaction with KAP among farmers (57.7%, 75.8% and 87.0%) and animal health staff (80.5%, 84.5%, and 78.3%) at ≥ 80% cut-off point of total score. The primary concern of farmers is involved in the understanding of the route of transmission and handwashing practices after contacting animals. Predictors of higher knowledge and positive attitude included province of residence and age. The factors linked to satisfactory practice levels consist of province of residence, educational level, and a history of family members’ infections (p < 0.05). Among animal health staff, the primary factor associated with KAP was province of residence, sex, level of education, and history of family members infection (p < 0.05). Additionally, brucellosis information primarily originated from traditional promotional materials and veterinarians.

Conclusions

This study emphasized that the KAP scores for both animal health staff and farmers were satisfactory, except for a suboptimal knowledge score among farmers. To proactively control future brucellosis outbreaks, it is imperative to develop targeted educational resources aimed at enhancing the understanding of brucellosis, particularly among farmers. Ensuring the availability and accessibility of informative materials for the effective prevention and control of brucellosis in livestock animals.
Crear, enseñar, transmitir el arte; desde su saber específico y su praxis
Authors: Vivas Ciarrusta Isusko
Published: January 2025

El objetivo principal del artículo pretende valorar las tareas y problemas de transmitir el arte, inmersos en los sistemas de enseñanza superior universitaria. Se aborda el reto ante el cual nos ubicamos para poder determinar la transmisión de las artes plásticas como campo de conocimiento autónomo y diferenciado, aunque interconectado; en interactuación constante con disciplinas y áreas del saber científico, técnico o humanístico. Estructuralmente, el texto se construye mediante cuatro ‘estadios’ entrelazados, siguiendo el corpus central una metodología argumentativa que indaga en los métodos re-transmisores, la recurrencia de las imágenes y de las palabras, así como la ‘transmisión de objetivos’ justificada por una operación estética sensible que alimenta las formas de hacer material para la creación en arte. Los resultados, no siempre concluyentes, abundan en la transmisión de dichas finalidades.
técnica release y contact-improvisation
Authors: Ardid Pérez Rosa Belén , Navalón Blesa Natividad
Published: January 2025

Surgidas durante la revolución de la danza posmoderna americana, la técnica release y el contact-improvisation fueron gestadas y se desarrollaron como procesos de aprendizaje basados en la investigación. Estas representaron un cuestionamiento a las dimensiones tradicionales del aprendizaje de danza y significó, tanto el descubrimiento de los principios de la técnica corporal a través de la comprensión de las leyes físicas en relación al movimiento y la anatomía de cada cuerpo, como la implicación creativa y personal del bailarín. Estas técnicas promueven una transformación en la manera de pensar el movimiento, que a su vez se convierte en una manera de generar pensamiento sobre el cuerpo, el compromiso personal y la visión social del arte de la danza. El propósito de este artículo es facilitar una contextualización teórica de los fundamentos humanistas y pedagógicos de las técnicas posmodernas release y contact-improvisation. La metodología parte de la recopilación bibliográfica y del análisis crítico que comienza con la consideración teórica del paradigma investigador y desciende hasta los estilos docentes bajo los cuales ambas técnicas se encuentran.
¿Es la educación plástica una asignatura necesaria en el currículum académico?
Authors: Muñecas Delgado Carlos
Published: January 2025

La educación plástica, frecuentemente relegada a un segundo plano en el currículum académico, tiene un valor crucial en la formación integral de los estudiantes. Este artículo presenta tres argumentos en defensa de su protección: el primero sostiene que el arte es una forma fundamental de transmitir la cultura, permitiendo a los estudiantes comprender su contexto histórico y social. El segundo argumenta que la educación plástica desarrolla competencias prácticas, al ser la única asignatura que trabaja con materiales físicos, lo cual es útil en muchos ámbitos. Por último, se defiende que el arte es un conocimiento esencial por derecho propio, tan valioso como las ciencias o las humanidades. Aunque los estudiantes no se dediquen profesionalmente al arte, entender los principios artísticos enriquece su visión del mundo. La educación plástica, por tanto, no solo es deseable, sino necesaria para una formación completa.
Transmisión de un saber corporal
Authors: González Francés Abián
Published: January 2025

La moda experimental o de vanguardia ha sido reconocida por cuestionar algunas convenciones en torno al cuerpo y su acercamiento a modos propios del arte contemporáneo. Esta investigación aborda dicha relación fijando la atención en el caso de Amberes, como lugar que desde la década de 1980 hasta la actualidad sigue exportando creadores y creadoras con visiones singulares alabadas por la escena internacional. Dentro de este contexto, el artículo analiza el origen de la moda entendida como arte y su transmisión pedagógica en el Departamento de Moda de la Real Academia de Bellas Artes de Amberes. La intención que subyace en todo el texto es la de tratar de hallar posibles puentes entre un saber corporal desde la moda y un saber corporal desde la escultura contemporánea, atendiendo a algunos acercamientos y conexiones ya existentes.
Laboratorios de prácticas artísticas en la comunidad
Authors: Sánchez Quinchuela Patricio
Published: January 2025

La verticalidad en la educación con el pasar del tiempo ha sido muy cuestionada al igual que sus paradigmas de enseñanza unilateral que parten desde la hegemonía social y económica de quien tiene el crédito o credibilidad de poseer el conocimiento o los saberes. Pues, de este hecho no es ajeno el campo artístico y cultural. En ese contexto, como una alternativa, presentamos la sistematización de una experiencia que aborda una asignatura transversal en la formación artística de profesionales de la Universidad de las Artes en Ecuador que a partir de una metodología y la dotación de herramientas prácticas para trabajo en campo, logran procesos inmersivos en zonas periféricas de la ciudad como barrios o comunidades en donde la articulación y entrelazamiento de la academia con la sociedad in-situ bajo el principio del diálogo de saberes, crea el escenario propicio para dinamizar el interaprendizaje basado en el compartir de conocimientos de todas las personas involucradas en el proceso dando espacio a la vez, a una vivencia intercultural que transforma las percepciones, visiones, estéticas y compromisos sociales a partir de conocer y convivir un espacio de tiempo con nuevas realidades y grupos humanos vulnerables que encuentran en las prácticas artísticas y culturales un medio educativo para transmitir y visibilizar su cultura.
Sobre el «Laboratorio experimental» de Jorge Oteiza
Authors: Rementeria Arnaiz Iskandar
Published: January 2025

Para abordar la noción de transmisión del saber específico del arte se ha optado aquí por analizar una suerte de diálogo estético entre dos escultores pertenecientes a distintas generaciones: Jorge Oteiza y Ángel Bados. El diálogo estético que se mantuvo entre estos dos artistas tomó distintas formas pero en el presente artículo se aborda concretamente el estudio que Bados realizó sobre el llamado ‘Laboratorio experimental’ de Jorge Oteiza. Este estudio tuvo tres formas de darse públicamente: una conferencia, un libro y una exposición que la Fundación Museo Jorge Oteiza encargó a Bados. Tomando como eje el ‘Laboratorio experimental’, se tratarán aquí cuestiones también de índole general relativas a la complejidad de la transmisión del saber específico del arte y su relación con la creación.
Diet supplementation with phytase and xylanase on laying performance, egg quality, apparent metabolizable energy, and phosphorous use in laying hens
Authors: Kayan Autchara , Prasongsook Sombat , Poeikhampha Theerawit
Published: January 2025

Background and Aim: The inclusion of supplementary enzymes, such as phytase and xylanase, in poultry diets enhances nutrient digestibility and reduces excreta output, minimizing environmental impact. This study aimed to evaluate the effects of phytase and xylanase supplementation on laying performance, egg quality, apparent metabolizable energy (AME), and phosphorus utilization in laying hens.

Materials and Methods: A total of 576 laying hens, aged 47 weeks, were randomly assigned to four dietary treatments: (T1) a control diet, (T2) a negative control diet with reduced energy and phosphorus, (T3) T2 supplemented with phytase (50 g/ton) and xylanase (100 g/ton), and (T4) T2 supplemented with phytase and NSP enzyme mix. The study was conducted over 12 weeks. Data on body weight, laying performance, egg quality, AME, and phosphorus utilization were analyzed using a one-way analysis of variance, with statistical significance set at p < 0.05.

Results: No significant differences were observed in hen-day egg production, egg weight, or feed intake across groups. However, enzyme supplementation (T3 and T4) significantly reduced feed costs per kg egg and feed cost per egg compared to the control (p < 0.05). Eggshell strength improved significantly in T3 and T4 groups, while yolk color declined in these groups compared to T1 (p < 0.05). Other quality metrics, such as albumen height and Haugh units, showed no significant differences. Apparent metabolizable energy, phosphorus retention time, and feces scores were not significantly affected by dietary treatments.

Conclusion: Phytase and xylanase supplementation in diets with reduced nutrient content effectively reduced production costs while maintaining laying performance and improving eggshell strength. These findings support the use of these enzymes as cost-efficient tools in poultry production without compromising egg quality.

Keywords: egg quality, feed efficiency, laying hen, nutrient digestability, phosphorus utilization, phytase, poultry enzymes, xylanase.
Kooperatív tanulás és csoportmunka az iskolában és a munkahelyen
Authors: Pelesz Nelli
Published: January 2025

„Az oktatás egyik alapfeltételezése, hogy a tanulók olyan készségeket sajátítanak el, melyeket később haszonnal tudnak alkalmazni munkájukban, családjukban és más területeken” (Rakaczkiné, Gombos és Nagy, 2009. 20. o.). A jelen és a jövő munkahelyei gyorsan és adekvát módon igyekeznek reagálni az egyre több és gyorsabban felmerülő kihívásra, a releváns válaszok egyike a szervezeti paradigma átalakítása, hatékonyabbá tétele. Az agilis szemléletmód, a proaktív hozzáállás, a team- és munkacsoportok felállítása ma már széles körben elterjedt, ezek központi eleme az együttműködés és a csoportmunka. Utóbbi nem tapasztalható és gyakorolható egyedül, illetve a hagyományos oktatásszervezési keretek között, a frontális osztálymunka erre nem ad lehetőséget. Az új, modernebb pedagógiai paradigma részeként a kooperatív tanulásszervezés alkalmazása során viszont a pedagógus arra törekszik, hogy az együttműködéshez és az egyéni és csoportteljesítményhez is egyaránt nélkülözhetetlen puha készségeket, szociális kompetenciákat fejlessze. A kooperatív tanulásszervezés saját élményű megtapasztalása, a hallgatók módszertani eszköztárába való beemelése biztosíthatja a sikeres iskolai előmenetelt, a társadalmi és munkahelyi beválást.
Educação ambiental crítica: uma reflexão sobre significados e sentidos entre estudantes universitários
Authors: Farias Luciana Aparecida , De Oliveira Borges Beatriz , Colagrande Elaine Angelina
Published: January 2025

O objetivo do presente estudo foi avaliar qual o efeito de sentido a palavra “Crítica” causa ao ser associada com a expressão “Educação Ambiental” quando apresentado para estudantes universitários de diferentes cursos de uma universidade pública. Esta pesquisa apresentou caráter qualitativo exploratório e contou com a participação de 102 estudantes, com a idade média de 21 anos. A aquisição dos dados ocorreu por meio da aplicação de um questionário estruturado e análise documental dos Projetos Pedagógicos dos Cursos. Os resultados obtidos evidenciaram diferentes sentidos para o termo indutor “Educação Ambiental”, bem como um desconhecimento geral a respeito da Educação Ambiental Crítica, o que evidencia a necessidade de se repensar estratégias de divulgação dessa corrente no campus participante do estudo, de maneira que os futuros profissionais saiam da universidade mais preparados para se tornarem também sujeitos ecológicos.
Machine Learning-Guided Fluid Resuscitation for Acute Pancreatitis Improves Outcomes
Authors: Kong Niwen , Chang Patrick , Ira Shulman , Haq Ubayd , Amini Maziar , Nguyen Denis , Khan Farhaad , Narala Rachan , Sharma Nisha , Wang Daniel , Thompson Tiana , Sadik Jonathan , Breze Cameron , Whitcomb David C. , Buxbaum James L.
Published: January 2025

OBJECTIVES:

Ariel Dynamic Acute Pancreatitis Tracker (ADAPT) is an artificial intelligence tool using mathematical algorithms to predict severity and manage fluid resuscitation needs based on the physiologic parameters of individual patients. Our aim was to assess whether adherence to ADAPT fluid recommendations versus standard management impacted clinical outcomes in a large prospective cohort.

METHOD:

We analyzed patients consecutively admitted to the Los Angeles General Medical Center between June 2015 to November 2022 whose course was richly characterized by capturing more than 100 clinical variables. We inputted this data into the ADAPT system to generate resuscitation fluid recommendations. and compared to the actual fluid resuscitation within the first 24 hours from presentation. The primary outcome was the difference in organ failure in those who were over (>500cc)- versus adequately (within 500cc) resuscitated with respect to the ADAPT fluid recommendation. Additional outcomes included ICU admission, SIRS at 48 hours, local complications, and pancreatitis severity.

RESULTS:

Among the 1083 patients evaluated using ADAPT, 700 were over-resuscitated,196 were adequately resuscitated, and 187 were under-resuscitated. Adjusting for pancreatitis etiology, gender, and SIRS at admission, over-resuscitation was associated with increased respiratory failure (Odd Ratio (OR) 2.73 [95%CI 1.06, 7.03]) as well as ICU admission (OR 2.40 [1.41, 4.11]), more than 48 hours of hospital length of stay (OR 1.87 [1.19, 2.94]), SIRS at 48 hours (OR 1.73 [1.08, 2.77]) and local pancreatitis complications (OR 2.93 [1.23, 6.96]).

CONCLUSIONS:

Adherence to ADAPT fluid recommendations reduces respiratory failure and other adverse outcomes compared to conventional fluid resuscitation strategies for acute pancreatitis. This validation study demonstrates the potential role of dynamic machine learning tools in acute pancreatitis management.
PERFORMANCES CULTURAIS E ARTÍSTICAS COM ARTISTAS SEM E COM DEFICIÊNCIA
Authors: Valério Póvoa Curado Renata , Dorneles de Lima Marlini , Campelo dos Santos Rosirene
Published: January 2025

Este trabalho parte da prática como pesquisa nas experiências teatrais realizadas junto ao Grupo de Dança Diversus, coletivo artístico vinculado à extensão da Universidade Federal de Goiás em Goiânia-GO, o grupo é formado por pessoas sem e com deficiência. As experiências nesse espaço de formação, produção artística e pesquisa são fundamentadas e analisadas, à luz dos estudos sobre a deficiência e sua relação com as artes da cena, da colaboração de escritos e reflexões de artistas def que pensam sobre a produção estética a partir da deficiência, entre outros autores e autoras que versam sobre corpos políticos e acessibilidade. O escrito transita pelo diálogo analitico critíco apoiado em pressupostos das Ciências Sociais, como a Antropologia em diálogo com a Arte, com a performance e performatividade, com camadas de inquietudes alicerçadas pela Estética do Performativo, para elaborar a noção de poéticas acessíveis e dramaturgias acessíveis como um dos desdobramentos do trabalho criativo e formativo neste grupo.
Resistirse al inquietante anonimato. El significado de la filiación en la filosofía de Emmanuel Lévinas
Authors: Hernández Castellón José Manuel
Published: January 2025

Ante la tendencia de la razón que reduce al ente humano a lo general, intentando despojarlo de lo que lo hace refractario al Todo, haciéndole manipulable, como si tratase de un objeto, hay que afirmar su individualidad. Hay que afirmarla porque lo propio de la homogeneidad es el instante y permanecer en el instante es hastío, ese tipo de hastío que es sufrimiento. ¿Cómo podríamos hacer esto de la mano del filósofo judío Emmanuel Lévinas? La filosofía levinasiana afirma la singularidad del ente humano anteponiendo la ética a la ontología. Es en la relación ética, y ante todo la relación paterno-filial, donde Lévinas estudia qué ocurre en la subjetividad al situarse frente al otro, pues en ella concurren las experiencias que muestran la salida de la homogeneidad del ser. Es decir, frente al hijo, al yo le sucede un despertar en cuanto que le aleja del instante, quedando los límites del tiempo dilatados.
La economía política y el espíritu del liberalismo: el factor del «dinero»
Authors: Medina Labayru Carlos
Published: January 2025

La economía ortodoxa oculta la cualidad esencial del dinero en tanto institución social de orden intelectual. En su lugar, lo presenta como una mercancía con el fin de ajustar de este modo su teoría del dinero al contexto teórico general del mercado como una esfera independiente del campo social que se autorregula virtuosamente por sí mismo, de manera natural, sin ninguna intervención externa. Sostengo que este sesgo naturalista tiene, no obstante, unos fundamentos que van más allá de una mera posición teórica dentro de los debates de la ciencia económica. Su trasfondo último está implícito en la propia ontología moderna de raíces nominalistas y calvinistas, que subyace al pensamiento liberal, y que juzga que las pretensiones de la razón humana acerca de un conocimiento cualitativo —fundado pues en la potencia noética de la imaginación— sobre el bien del hombre y la sociedad son intrínsecamente ilegítimas.
Shaping the Future of “Cardio-Kidney-Metabolic” Health: Insights From The Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference
Authors: Raghuram Arjun , Sprung Keri , Coulter Stephanie , Rogers Joseph G.
Published: January 2025

At the Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference, held on August 23, 2024, experts from diverse academic fields spoke about novel initiatives for addressing the worsening projections for cardiometabolic syndrome. Four major areas in which innovation is ongoing were highlighted: technology, policy, population health, and lifestyle and behavioral modification. This article presents a brief contextualization, summary, and analysis of the novel initiatives being implemented in each of these 4 areas to address cardiometabolic syndrome. Despite alarming projections, cardiometabolic syndrome presents a unique opportunity for innovators to drive change through collaborative, multidisciplinary efforts.
Exploring genetic variability, diversity and trait associations in sunnhemp (Crotolaria juncea L.) accessions for yield improvement
Authors: Pushpa R , Shanmugam A , Arulmozhi R , Sassikumar D , Suresh R , Subrahmaniyan K
Published: January 2025

Sunnhemp (Crotolaria juncea L.) is an important fibre crop known for its rapid growth and ability to improve soil fertility, making it a vital component of sustainable agriculture. However, to enhance its productivity and meet the increasing demand for high-quality fibre, it is crucial to identify and utilize genetically diverse genotypes with superior yield traits. The present study was conducted at the Tamil Nadu Rice Research Institute, Aduthurai, Tamil Nadu, during the Kharif seasons of 2021 and 2022 to assess genetic variability and character association for yield and its component traits among 67 sunnhemp genotypes. Multivariate analyses, including principal component analysis (PCA) and cluster analysis, were conducted using R software to dissect the phenotypic diversity among the genotypes. The results revealed substantial genetic variability for yield and its associated traits, indicating a promising potential for genetic improvement. Genotypes ADSH 1750, ADSH 1701, ADSH 1736, ADSH 1715, and ADSH 1742 exhibited superior performance in key yield-related traits, making them valuable candidates for future breeding programs focused on developing high-yielding, high-fibre varieties. Cluster analysis delineated four distinct clusters, with Clusters I and IV showing significant divergence and highlighting the presence of unique genetic material. Key plant production traits such as plant height, leaf breadth, basal stem diameter, yield, and number of leaves were the primary contributors to the first two principal components. These findings suggest that direct selection based on these traits could effectively improve biomass yield in future sunnhemp breeding efforts, contributing to the advancement of sustainable fibre crop production.
Long-term follow-up results and complications of breast-conserving surgery using multilayer acellular dermal matrix: a retrospective study
Authors: Seo Jung Yeol , Seo Kwang Sik , Lee Jae Woo , Oh Won Seok , Bae Seong Hwan , Jung Youn Joo , Nam Su Bong
Published: January 2025

Background The advantages of using an acellular dermal matrix (ADM) for implantbased breast reconstruction in breast cancer patients are well-documented across multiple studies. However, there have been no previous instances of using multilayered ADM for reconstruction following breast-conserving surgery (BCS). This study evaluated the outcomes of breast reconstruction employing multilayered ADM for volume replacement using a local glandular flap post-BCS, and aims to underscore the advantages of this surgical approach.Methods Breast cancer patients who underwent BCS using several layers of ADM from August 2016 to December 2019 were retrospectively reviewed. Only patients with at least 3 years of follow-up were included in this study. The anticipated postoperative complications were breast deformity, seroma, hematoma, and infection.Results Seventy-four patients were included in this study. Most patients experienced symptoms of hard palpation at the reconstruction site, which indicated the surface of the ADM inserted into the breast. Ten patients developed breast deformities, accounting for 13.5% of the cases, and required surgical correction. Other complications were less frequent: four patients (5.3%) had a confirmed seroma for 6 months or longer, two patients (2.6%) experienced fat necrosis, and one patient (1.3%) underwent re-operation to remove the ADM.Conclusions Reconstruction with a glandular flap and ADM following BCS is generally simpler and requires less surgical time compared to using a latissimus dorsi flap or other local flaps. Additionally, it avoids complications at the donor site, presenting a feasible surgical alternative for BCS in breasts with small defects.
Rare Prevotella bivia infection after liposuction and fat graft: two case reports
Authors: Lee Jooyeop , Yun In Sik , Roh Tai Suk , Kim Young Seok , Min Kyunghyun
Published: January 2025

Liposuction and fat grafting are commonly employed to improve body contouring. While postoperative infections are infrequent, severe complications like necrotizing fasciitis can arise, potentially destroying the aesthetic results. Prevotella bivia is an anaerobic, Gram-negative rod bacterium commonly found in the vaginal mucosa, with increased prevalence in cases of bacterial vaginosis. Infections caused by this species can lead to necrotizing fasciitis or extensive tissue necrosis, necessitating prompt diagnosis during the acute phase. This report presents two severe cases of infection caused by P. bivia following fat harvesting and grafting procedures. These cases required multiple debridements, skin grafts, and fasciotomies for management.
Cylinders in smooth del Pezzo surfaces of degree 2
Authors: Kim Jaehyun , Won Joonyeong
Published: January 2025

We find a criterion that completely characterizes the existence of ample polar cylinders of Fujita rank 2 in smooth del Pezzo surfaces of degree 2.
Relevance and effectiveness in translation planning into minoritized languages: an evaluation of translation subsidies in the Galician publishing industry
Authors: García González Marta
Published: January 2025

Since the approval of the Estatuto de Autonomía de Galicia (EAG) in 1981, Galician has undergone continuous language planning (LP) efforts. While several authors have examined various aspects of this planning process, studies evaluating the overall relevance and effectiveness of measures remain limited. To contribute to this evaluation, this study examines the use of translation as a means of LP for Galician. After providing an overview of translation as a fundamental tool in minority LP, the paper focuses on the Galician publishing industry, which has been consistently subsidized by the Galician government to promote language development. Specifically, the paper looks for correlations between subsidies for translation into Galician (inputs), translations published in Galician (outputs) and citizens using the minoritized language and consuming books and cultural products (outcomes), based mainly on data from regional government sources and the publishing industry. In analysing the use of translation subsidies as a LP strategy, this paper seeks to shed light on their relevance and effectiveness in contributing to the development of the Galician language. Also, the evaluation of translation-based measures in the publishing industry provides valuable insights into the success of these initiatives and their impact on language vitality.
Microstructure and mechanical properties of dissimilar resistance spot welds of TBF and HSLA300 steel sheets
Authors: Ozturk Yilmaz Imren , Aydın Hakan
Published: January 2025

The welding behavior of the resistance spot welded dissimilar TBF–HSLA300 steel joints under different welding parameters was investigated. TBF steels were used as galvanized or ungalvanized. Microstructural characterization and mechanical tests were performed. Higher heat input resulted in the higher possibility of shrinkage cavities at the weld nugget and also increased the risk of liquid metal embrittlement (LEM) crack in the heat affected zone (HAZ) on galvanized TBF steel sheets. A partial melting zone was observed on HSLA300 side. The welds with ungalvanized TBF sheets had the higher nugget size and indentation. The highest hardness values (over 500 HV0.1) were observed in HAZ on TBF side. The lowest hardness values (below 300 HV0.1) on TBF side were observed in a very narrow softening zone between tempered zone and base metal. The fractures of all spot welds in the tensile shear test occurred on the TBF steel side with the thinner thickness. Low-strength steel sheet have to be sufficiently thicker in order to achieve higher welding strength. Higher welding time led to higher weld strength in the ungalvanized TBF combination. In the galvanized TBF combination, higher heat input led to the drastic decrease in weld strength due to LEM cracks.
The evolution of research articles on self-denigration: a systematic review across disciplines
Authors: Mayahi Nadia , Jalilifar Alireza
Published: January 2025

This systematic review explored self-denigration in research articles published across different disciplines in the past four decades. Following a comprehensive collection and screening of data (4,002 initial records) from four scholarly databases, 80 research articles that met our eligibility criteria were identified. In line with the objectives of this study, the publications were coded and analyzed for contextual, methodological, and theoretical dimensions. The review also adopted an in-depth synthesis of the research articles investigating the attitudes of individuals toward self-denigration, and probed the development of research foci in this area. Among other results, the study revealed that the participants in the vast majority of studies effectively employed self-denigration as a relational communication management strategy. Contrary to our expectations, findings provided evidence for the widespread popularity of research on self-denigration in Western contexts, most of which report a favorable account of using self-denigration in social interactions away from its face value. Accordingly, this area deserves further exploration in different disciplines and contexts, as the study has practical significance in managing different interactional predicaments.
The lithium-rich stannide Li4Rh3Sn5
Authors: Sreeraj Puravankara , Dinges Tim , Kösters Jutta , Schappacher Falko M. , Eckert Hellmut , Pöttgen Rainer
Published: January 2025

The stannide Li4Rh3Sn5 was synthesized by induction-melting of the elements in a sealed tantalum ampoule. The sample was characterized by powder X-ray diffraction and the Li4Rh3Sn5 structure was refined from single-crystal X-ray diffractometer data: new type, orthorhombic space group Pnnm, a = 813.27(11), b = 2,259.6(3), c = 449.94(6) pm, wR2 = 0.0486, 1577 F
2 values and 64 variables. The rhodium and tin atoms form a rigid covalently bonded three-dimensional [Rh3Sn5] network with Rh–Sn distances ranging from 263 to 277 pm. Within this network, the tin atoms form two different substructures, i. e., angled Sn1–Sn4–Sn5 units and isolated Sn2 and Sn3 atoms. The lithium atoms fill cages within the [Rh3Sn5] network. They have coordination numbers 11, 12 and 13. Based on their different 7Li resonance shifts two groups of distinct local environments can be identified in an intensity ratio of 3:1, namely the 4g Wyckoff sites Li1, Li2, and Li5, and the 2c Wyckoff sites Li3 and Li4. The whole Li4Rh3Sn5 structure can be described by condensation of the Li1@LiRh4Sn6, Li2@Li2Rh4Sn6, Li3@Li2Rh4Sn6, and Li4@Li2Rh4Sn6 polyhedra, including the Li5 atoms which are within the Li1 coordination sphere. The 119Sn Mössbauer spectrum of Li4Rh3Sn5 shows a superposition of two sub-signals in a ratio of 60:40. The two sub-signals with similar isomer shift are discernable through their quadrupole splitting parameters: ∼1.93 mm s−1 for the tin atoms of the angled Sn3 unit, and ∼1.20 mm s−1 for the isolated tin atoms with a more symmetric electron density distribution.
Establishment of critical values for AMH screening with PCOS based on restricted cubic spline plots
Authors: Wang Zhen , Teng Xiaojing , Shen Yonghai , Liu Yanfei
Published: January 2025

Background

The aim is to develop age-specific anti-Müllerian hormone (AMH) screening criteria for polycystic ovary syndrome (PCOS) to facilitate early detection and diagnosis of the condition and subsequently evaluate the screening criteria.

Methods

A retrospective analysis was performed on patient data from Hangzhou Women’s Hospital between July 2021 and August 2024. The use of restricted cubic spline analysis helped identify age-related inflection points, which were crucial for segmenting the patient population. Statistical analysis was conducted using SPSS software, and the receiver operating characteristic curve was employed to determine the area under the curve, optimal AMH screening thresholds, sensitivity, specificity, Youden index, correct diagnosis rate, positive predictive value and negative predictive value. The established age-related AMH screening criteria for PCOS were then validated using a separate validation group. The consistency of the PCOS age-related AMH screening test with the 2003 Rotterdam PCOS diagnostic criteria was assessed using the kappa statistic.

Results

The derived age-specific AMH screening thresholds for PCOS are as follows: ≥6.93 ng/mL (20–27 years old), ≥5.06 ng/mL (28–30 years old) and ≥4.19 ng/mL (31–39 years old).

Conclusion

The age-stratified AMH screening criteria demonstrated high sensitivity, specificity and accuracy in identifying PCOS, indicating a strong predictive value. However, the development of more robust and universally applicable diagnostic criteria for PCOS will require additional multicenter, prospective clinical trials for further validation.
The natural course of cystic pancreatic neuroendocrine tumours in MEN1
Authors: van Vliembergen Eline N M , Pieterman Carolina R C , van de Ven Annenienke C , Braat Arthur J A T , Valk Gerlof D , de Laat Joanne M
Published: January 2025

Pancreatic neuroendocrine tumours (PanNETs) significantly impact life expectancy in multiple endocrine neoplasia type 1 (MEN1). Both solid and cystic pancreatic lesions are observed in MEN1, yet limited research has been focused on cystic lesions in MEN1. While solid PanNETs are generally considered to have an indolent course, the natural course of cystic lesions remains unclear. This study aims to provide more insights into the natural course of cystic PanNETs in MEN1. Patients with MEN1 and radiologically suspected PanNETs, treated at UMC Utrecht and Radboudumc between 2010 and 2023, were included. In the first part, we examined the characteristics of patients with tumours visible on imaging scans. In the second part, we investigated outcomes of pathological examinations, following resection of these lesions. A total of 136 patients were included, comprising 60 men and 76 women. The median follow-up was 5.1 years. [68Ga]Ga-DOTATOC PET/CT scans showed that both cystic and solid lesions demonstrated [68Ga]Ga-DOTATOC PET/CT uptake. The median growth of cystic and solid PanNETs was similar. Pathological examination of 38 resected tumours confirmed that cystic lesions identified on imaging were indeed PanNETs. Cystic lesions had a median diameter of 26 mm at the time of resection, compared to 18 mm for solid lesions, with comparable Ki-67 indices and mitotic counts. We conclude that cystic and solid PanNETs in MEN1 patients appear to be morphological variations of the same entity, suggesting that similar management approaches should be considered.
Surgical planning of small intestine neuroendocrine tumors: the concept of mesenteric tumor deposits
Authors: L’Huillier Romain , Poncet Gilles , Pasquer Arnaud , Walter Thomas , Lombard-Bohas Catherine , Hervieu Valérie , Cayot Bénédicte , Valette Pierre-Jean , Cheung Helen , Milot Laurent
Published: January 2025

The mesenteric extension of small neuroendocrine tumors is the surgical limiting factor because of the risk of postoperative short bowel syndrome due to superior mesenteric artery involvement. Recent pathological studies have shown that this vascular involvement is due to mesenteric tumor deposits, differentiated from lymph node metastases. The aim of this study was to evaluate the performances of computed tomography (CT) for the surgical planning of small intestine neuroendocrine tumors. This was a retrospective observational study, and all patients undergoing surgery for small intestine neuroendocrine tumor between January 2014 and March 2019 were included. Preoperative CTs were reviewed, blinded from surgical and pathological data, by two radiologists. Diagnostic accuracy and interobserver reliability analysis were performed. We included 45 patients (mean age: 61 years (28–84 years); 23 men). The CT sensitivity to identify the mesenteric mass was 97% (37/38) with a ĸ of 0.73. The positive predictive value of CT to anticipate a right colic resection was 86% (18/21). The negative predictive value of CT was high (97% (34/35) to 100% (35/35)) for duodenal resection (ĸ = 0.78). Regarding retropancreatic lymph node invasion, the CT sensitivity was poor (24%, 4/17), with a high ĸ (0.88). The level of involvement by the mesenteric mass was correlated with the length and the percentage of the remaining small bowel. CT is essential for the surgical planning of small intestine neuroendocrine tumors, being accurate in defining the mesenteric tumor deposits, allowing one to anticipate, with a good reproducibility, the length and percentage of the remaining small bowel and the necessity for a right colectomy.
Thyroid differentiation profile for differentiated thyroid cancer
Authors: McGoron Anthony J , Garcia Jose M , Uluvar Burulça , Gulec Seza A
Published: January 2025

Radioactive iodine (RAI) treatment is an established therapeutic tool for ‘differentiated thyroid cancers’. The therapeutic effectiveness is linked to the preservation of the iodine-concentrating ability of the neoplastic tissue, a unique, inherent quality of a normal thyroid gland. Iodine concentration is a function involving the expression of transport proteins and organification. Thyroid differentiation score (TDS) is an integrated quantity, first introduced by The Cancer Genome Atlas (TCGA), conveying the relative expression of proteins involved in histogenesis, morphologic and functional differentiation of thyroid tissue. The concept is well described for the expression of metabolic suppression of thyroid cancers associated with RAI-refractoriness. We evaluated the mRNA expressions of thyroid metabolomics-specific genes, comparing normal thyroid to neoplastic tissue in a cohort where patient-specific paired data were available. Fifty-nine papillary thyroid cancer samples from the TCGA project with matched tumor-normal tissue samples were analyzed. Of the 59 samples, 29 contained a BRAFV600E mutation, seven a RAS mutation, 10 a mutation other than BRAF or RAS, and 14 either no mutation or an unknown mutation. Our analysis demonstrated that there was a significant downregulation of the RAI theranostic transcriptome, much more significant in BRAF-initiated cancers vs RAS-initiated ones. There was also notable heterogeneity in respective mutational categories where individual assessment of the thyroid differentiation profile (TDP) would potentially be clinically relevant for RAI treatment planning. Determination of TDP and development of a theranostic TDS may have an impact on clinical decision making as to the extent of thyroidectomy and postoperative RAI therapy.
Diminazene aceturate, an ACE2 activator, ameliorates testicular injury in diet-induced obese mice
Authors: Yue Xiaofeng , Yin Rui , Wu Liling , Li Jinjin , Wang Jianwu , Yan Benhuang , Dai Lingyong , Shen Chongxing , Zhi Yi , Wan Ling , Yang Jigao , Li Weibing
Published: January 2025

In brief

Obesity is a prevalent health concern globally, often associated with testicular damage that can lead to male infertility. This study investigates the improvement of obesity-induced testicular damage by ACE2 agonist diminazene aceturate (DIZE) and explores the role of the ACE2/Ang 1–7/MasR axis in this process.

DIZE improved obesity and metabolic disturbances in diet-induced obesity (DIO) mice. An increase in sperm count and motility, along with improved morphology and increased male fertility, was observed after DIZE treatment. Both serum and intratesticular testosterone levels showed an increase. Moreover, ACE2/Ang 1–7/MasR protein levels in the testes were restored, which inhibited germ cells apoptosis, lipid accumulation and oxidative stress, and elevated testosterone synthesis-related proteins. However, the MasR antagonist A779 partially counteracted the improving effects of DIZE on metabolism and the testes of DIO mice. This study shows that DIZE treatment has protective effects against obesity-induced testicular injury by activating the ACE2/Ang 1–7/MasR axis.
Colonizadores del mundo queremos que todo nos hable. Poéticas de los reflejos
Authors: Cornago Óscar
Published: January 2025

El reflejo es una imagen-dispositivo que despliega una temporalidad singular en la que la percepción lineal y progresiva del tiempo queda suspendida. A partir de esta aproximación este artículo traza un recorrido por contextos y proyectos diversos que van desde las artes visuales, la exposición, el archivo, el video, el cine y el teatro. El denominador común son los reflejos como una operación en el tiempo que activa una transformación, en el sentido literal de pasar de una forma a otra, así como una política de la mirada. Las referencias que se manejan describen, al igual que los reflejos, un movimiento de ida y vuelta, entre los años sesenta y setenta, cuando el vídeo y la performance se descubren como modos de trabajo en tiempo real, y el momento actual en el que estos planteamientos han sido asimilados por la tecnología digital como características transversales del medio artístico.
Effect of timber harvesting techniques and slopes on soil respiration of young and mature black pine stands in northwestern Türkiye
Authors: Özer Genç Çiğdem , Sarıyıldız Temel , Arıcak Burak
Published: January 2025

Releases of CO2 from forest soils was studied relative to different timber harvesting techniques, slope classes, and stand age. Three timber harvesting techniques (suspended skidding (SS), skidding by using a skidding cone (SC), and cable-pulling (CP)) were used in young and mature black pine stands at three different slopes (0 to 20% – S1, 20% to 33% – S2, and > 33% – S3). Soil respiration measurements were carried out at five-day intervals (1st, 5th, and 10th day) and 6 months later after the timber harvesting techniques. The soil respiration increased on the first day, decreased on the 5th and 10th days, and reached its lowest level on the 6th month. The SC technique in the young stands showed the highest soil respiration value on the slopes indicating that the cone placed on the head of the log during the skidding operations does not deform the soil. In the mature stands, all timber harvesting techniques and the undisturbed sites showed lower values than in the young stands on the S1. On the S2, mean value was higher in the mature stands. In contrast to the young stands, the undisturbed stands had the highest soil respiration.
Minimally destructive bamboo property estimation of Phyllostachys makinoi using drilling resistance method
Authors: Lin Cheng-Jung , Lin Po-Heng
Published: January 2025

Drilling resistance amplitude was used to estimate properties such as density, modulus of elasticity (MOE), and modulus of rupture (MOR) in Phyllostachys makinoi bamboo. The purpose of this study was to replace subjective visual estimation with a scientific method, using drilling resistance to estimate bamboo maturity, thereby providing a basis for selecting high-quality bamboo materials. The results indicated significant linear correlations between both average and maximum drilling amplitudes and bamboo density, MOE, and MOR. The coefficients of determination (R²) for average and maximum drilling amplitude with bamboo density ranged between 0.55 and 0.56, and a significant linear correlation was also observed between average and maximum drilling amplitudes (R² = 0.75). Additionally, the profile curve of drilling resistance amplitude varied significantly across the thickness of the bamboo culm. From the culm surface inward (bamboo skin, flesh layer, and cavity layer), the amplitude rose rapidly, reaching a peak at approximately 28% of culm thickness, then gradually decreased, with a secondary reduction observed around 67% of the thickness, eventually reaching the hollow core. Based on these findings, maximum drilling amplitude could serve as an indicator of bamboo density and may be applied as a minimally destructive technique