bluuebunny/crossref_metadata_2025 huggingface dataset:
AGRICULTURA FAMILIAR E DESENVOLVIMENTO NA PARAÍBA: O AGROAMIGO COMO ATOR SOCIAL
Authors: Gomes Ramonildes Alves , Miranda Roberto Sousa , Meneses Valdenio Freitas
Published: October 2023

No artigo nos propomos a analisar o Programa Agroamigo no estado da Paraíba, refletindo sobre a sua trajetória enquanto um ator social indutor de mudanças que impactam o desenvolvimento rural. Tomamos como fontes de evidências o acervo bibliográfico que discute e analisa o programa e as suas operações de crédito a Paraíba, entre os anos de 2007 e 2022, disponibilizadas pelo BNB. Chamamos a atenção para a importância de se problematizar a articulação entre o Agroamigo e o dinamismo da agricultura familiar, que converge para o desenvolvimento de espaços rurais frágeis, como no Agreste e no Sertão paraibano. Questionamos como o Agroamigo tem contribuído para reorganizar a agricultura familiar e desenvolver esses espaços, e quais as inovações e mudanças contaram com a sua influência. Mostramos, ao final, que o Agroamigo possui uma grande capilaridade, custeando e investindo na agricultura familiar de todos os municípios paraibanos, especialmente, nos mais pobres, que as mulheres são as maiores tomadoras de crédito para as atividades agrícolas e que as vulnerabilidades climáticas não são obstáculo para acessar o crédito.
Análise dos gastos da Coordenadoria em Vigilância em Saúde de São Paulo no período de 2009 a 2019
Authors: Alves de Oliveira Rafaella
Published: October 2023

A vigilância sanitária tem papel importante no Sistema Único de Saúde ao atuar na fiscalização de produtos e serviços de interesse da saúde cuja implementação depende do financiamento de suas ações. Na cidade de São Paulo, o órgão responsável por coordenar as ações de vigilância sanitária é a Coordenadoria de Vigilância em Saúde (Covisa). O presente trabalho tem por objetivo esclarecer onde foram alocados os recursos destinados à Covisa, em especial aqueles destinados à vigilância sanitária, nos anos de 2009 a 2019. Para isso, foram coletados dados da execução orçamentária do Quadro Detalhado de Despesas (QDD) disponíveis no sítio eletrônico da Prefeitura Municipal de São Paulo. Entre os resultados encontrados estão o fato de que o orçamento da Covisa não chega a 1% do orçamento da SMS. Em 2009, não foi destinada verba à subfunção vigilância sanitária. De 2010 a 2013, os valores direcionados para a vigilância sanitária foram gastos com o Centro de Controle de Zoonoses (CCZ). Em 2014, os gastos passaram a ser identificados genericamente como Vigilância em Saúde. Naquele momento, houve um pico de gastos e, desde então, os valores foram reduzindo ano a ano. Os resultados indicam que a vigilância sanitária ocupa papel marginalizado nas políticas de saúde da cidade de São Paulo. Em que pese aos avanços na alocação de recursos de 2014 em diante, destaca-se a necessidade da construção de uma política de financiamento e ampliação da discussão sobre financiamento com recursos próprios.
revisão do Plano Diretor Estratégico
Authors: Maglio Ivan Carlos
Published: October 2023

Artigo de opinião sobre o processo de revisão do Plano Diretor Estratégico de São Paulo, em 2023.
Portal SME
Authors: Romboli Magali Seravalli , Saleh Samira
Published: October 2023

O presente artigo tem como objetivo analisar a formação da agenda governamental que favoreceu a reestruturação do Portal da Secretaria Municipal de Educação de São Paulo, a partir do debate público proposto à sociedade pelo Programa de Reorganização Curricular e Administrativo, Ampliação e Fortalecimento da Rede Municipal de Educação de São Paulo – Programa Mais Educação São Paulo – durante a gestão do prefeito Fernando Haddad (2013/2016). Partiu-se da hipótese de que a gestão compartilhada da informação desenvolvida durante o debate e consulta pública do Programa Mais Educação São Paulo favorece a criação coletiva de uma multiplataforma de comunicação e informação digital, e que do ponto de vista teórico está em consonância com os conceitos propostos pelos múltiplos fluxos, vistos em Kingdon (2003). Ao final de nossa investigação qualitativa, ficou evidente a contribuição da comunidade escolar e da sociedade para legitimar o novo portal para a Secretaria Municipal de Educação de São Paulo.
РЕГИОНАЛНA ДИФЕРЕНЦИЈАЦИЈA СТРУКТУРНИХ ПРОМЈЕНА ЗАПОСЛЕНОСТИ СТАНОВНИШТВА РЕПУБЛИКЕ СРПСКЕ
Authors: Делић Драгица , Сабљић Лука
Published: October 2023

Рад анализира промјене у запослености по секторима привреде у Републици Српској и њеним нодал- но-функционалним регијама у периоду 2009–2019. године. Анализа промјена у структури запослених урађена је методом промјене удјела (shift-share) како би се утврдило да ли су укупни учинци промјена запослености у регијама у односу на национални просјек резултат његове економске структуре и/или стопа раста његових сектора. Посматрано је кретање броја запослених на националном нивоу (у овом случају нивоу Републике Српске), регионалном нивоу (регије Републике Српске) и локалном нивоу (градови и општине у припадајућим регијама). Резултати указују на изражену регионалну неједнакост у запослености. Национална компонента запослености, то јесте промјена узроко- вана националним трендом, највећа је у Бањалучкој регији, затим у Добојско-бијељинској и Сарајевско-зворничкој регији, а најмања у Требињско-фочанској регији. Резултати анализе секторске компоненте указују на то да кретање броја запослених на националном нивоу негативно утиче на кретање броја запослених на нивоу свих регија у прва три сектора, од којих је највећа негативна промјена забиљежена у секундарном сектору у свим регијама. Позитивну вриједност промјене биљежи само квартарни сектор, највећу у Бањалучкој регији, а најмању у Требињско-фочанској регији. Резултати анализе локалне компоненте на нивоу регија Републике Српске указују на то да само Бањалучка регија има конкурентске предности када је у питању кретање укупног броја запослених.
Three de-intuitionistic fuzzification procedures over circular intuitionistic fuzzy sets
Authors:   Institute of Information and Communication Technologies, Bulgarian Academy of Sciences, Atanassova Lilija
Published: October 2023

Circular Intuitionistic Fuzzy Sets (CIFS) are one of the newest extensions of the intuitionistic fuzzy sets. In the present paper, three procedures for de-intuitionistic fuzzification of CIFS are discussed.
A toxin-antidote selfish element increases fitness of its host
Authors: Long Lijiang , Xu Wen , Valencia Francisco , Paaby Annalise B , McGrath Patrick T
Published: October 2023

Selfish genetic elements can promote their transmission at the expense of individual survival, creating conflict between the element and the rest of the genome. Recently, a large number of toxin-antidote (TA) post-segregation distorters have been identified in non-obligate outcrossing nematodes. Their origin and the evolutionary forces that keep them at intermediate population frequencies are poorly understood. Here, we study a TA element in Caenorhabditis elegans called zeel-1;peel-1. Two major haplotypes of this locus, with and without the selfish element, segregate in C. elegans. We evaluate the fitness consequences of the zeel-1;peel-1 element outside of its role in gene drive in non-outcrossing animals and demonstrate that loss of the toxin peel-1 decreased fitness of hermaphrodites and resulted in reductions in fecundity and body size. These findings suggest a biological role for peel-1 beyond toxin lethality. This work demonstrates that a TA element can provide a fitness benefit to its hosts either during their initial evolution or by being co-opted by the animals following their selfish spread. These findings guide our understanding on how TA elements can remain in a population where gene drive is minimized, helping resolve the mystery of prevalent TA elements in selfing animals.
A scalable and tunable platform for functional interrogation of peptide hormones in fish
Authors: Moses Eitan , Franek Roman , Harel Itamar
Published: October 2023

Pituitary hormones play a central role in shaping vertebrate life history events, including growth, reproduction, metabolism, and aging. The regulation of these traits often requires precise control of hormone levels across diverse timescales. However, fine tuning circulating hormones in-vivo has traditionally been experimentally challenging. Here, using the naturally short-lived turquoise killifish (N. furzeri), we describe a high-throughput platform that combines loss- and gain-of-function of peptide hormones. Mutation of three primary pituitary hormones, growth hormone (gh1), follicle stimulating hormone (fshb), and thyroid stimulating hormone (tshb), alters somatic growth and reproduction. Thus, suggesting that while the killifish undergoes extremely rapid growth and maturity, it still relies on vertebrate-conserved genetic networks. As the next stage, we developed a gain-of-function vector system in which a hormone is tagged using a self-cleavable fluorescent reporter, and ectopically expressed in-vivo through intramuscular electroporation. Following a single electroporation, phenotypes, such as reproduction, are stably rescued for several months. Notably, we demonstrate the versatility of this approach by using multiplexing, dose-dependent, and doxycycline-inducible systems to achieve tunable and reversible expression. In summary, this method is relatively high-throughput, and facilitates large-scale interrogation of life-history strategies in fish. Ultimately, this approach could be adapted for modifying aquaculture species and exploring pro-longevity interventions.
Orai mediated Calcium entry determines activity of central dopaminergic neurons by regulation of gene expression
Authors: Mitra Rishav , Richhariya Shlesha , Hasan Gaiti
Published: October 2023

Maturation and fine-tuning of neural circuits frequently requires neuromodulatory signals that set the excitability threshold, neuronal connectivity and synaptic strength. Here we present a mechanistic study of how neuromodulator stimulated intracellular Ca
2+
signals, through the store-operated Ca
2+
channel Orai, regulate intrinsic neuronal properties by control of developmental gene expression in flight promoting central dopaminergic neurons (fpDANs). The fpDANs receive cholinergic inputs for release of dopamine at a central brain tripartite synapse that sustains flight (Sharma and Hasan, 2020). Cholinergic inputs act on the muscarinic acetylcholine receptor to stimulate intracellular Ca
2+
release through the endoplasmic reticulum (ER) localised inositol 1,4,5-trisphosphate receptor followed by ER-store depletion and Orai mediated store-operated Ca
2+
entry (SOCE). Analysis of gene expression in fpDANs followed by genetic, cellular and molecular studies identified Orai-mediated Ca
2+
entry as a key regulator of excitability in fpDANs during circuit maturation. SOCE activates the transcription factor Trithorax-like (Trl) which in turn drives expression of a set of genes including
Set2
, that encodes a histone 3 Lysine 36 methyltransferase (H3K36me3). Set2 function establishes a positive feedback loop, essential for receiving neuromodulatory cholinergic inputs and sustaining SOCE. Chromatin modifying activity of Set2 changes the epigenetic status of fpDANs and drives expression of key ion channel and signaling genes that determine fpDAN activity. Loss of activity reduces the axonal arborisation of fpDANS within the MB lobe, and prevents dopamine release required for maintenance of long flight.Store-operated Ca
2+
entry (SOCE) through Orai is required in a set of flight-promoting central dopaminergic neurons (fpDANs) during late pupae and early adults to establish their gene expression profile.SOCE activates a homeobox transcription factor, ‘
Trithorax-like
’ and thus regulates expression of histone modifiers Set2 and
E(z)
to generate a balance between opposing epigenetic signatures of H3K36me3 and H3K27me3 on downstream genes.SOCE drives a transcriptional feedback loop to ensure expression of key genes required for neuronal function including the muscarinic acetylcholine receptor (
mAChR
) and the inositol 1,4,5-trisphosphate receptor (
itpr)
.The transcriptional program downstream of SOCE is key to functional maturation of the dopaminergic neurons, enabling their neuronal excitability, axonal arborization and synaptic transmission required for adult flight.
Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction
Authors: Latini Sara , Venafra Veronica , Massacci Giorgia , Bica Valeria , Graziosi Simone , Pugliese Giusj Monia , Iannuccelli Marta , Frioni Filippo , Minnella Gessica , Marra John Donald , Chiusolo Patrizia , Pepe Gerardo , Helmer Citterich Manuela , Mougiakakos Dimitros , Böttcher Martin , Fischer Thomas , Perfetto Livia , Sacco Francesca
Published: October 2023

Currently, the identification of patient-specific therapies in cancer is mainly informed by personalized genomic analysis. In the setting of acute myeloid leukemia (AML), patient-drug treatment matching fails in a subset of patients harboring atypical internal tandem duplications (ITDs) in the tyrosine kinase domain of the FLT3 gene. To address this unmet medical need, here we develop a systems-based strategy that integrates multiparametric analysis of crucial signaling pathways, and patient-specific genomic and transcriptomic data with a prior knowledge signaling network using a Boolean-based formalism. By this approach, we derive personalized predictive models describing the signaling landscape of AML FLT3-ITD positive cell lines and patients. These models enable us to derive mechanistic insight into drug resistance mechanisms and suggest novel opportunities for combinatorial treatments. Interestingly, our analysis reveals that the JNK kinase pathway plays a crucial role in the tyrosine kinase inhibitor response of FLT3-ITD cells through cell cycle regulation. Finally, our work shows that patient-specific logic models have the potential to inform precision medicine approaches.
Body size as a metric for the affordable world
Authors: Feng Xinran , Xu Shan , Li Yuannan , Liu Jia
Published: October 2023

The physical body of an organism serves as a vital interface for interactions with its environment. Here, we investigated the impact of human body size on the perception of action possibilities (affordances) offered by the environment. We found that the body size delineated a distinct boundary on affordances, dividing objects of continuous real-world sizes into two discrete categories with each affording distinct action sets. Additionally, the boundary shifted with imagined body sizes, suggesting a causal link between body size and affordance perception. Intriguingly, ChatGPT, a large language model lacking physical embodiment, exhibited a modest yet comparable affordance boundary at the scale of human body size, suggesting the boundary is not exclusively derived from organism-environment interactions. A subsequent fMRI experiment offered preliminary evidence of affordance processing exclusively for objects within the body size range, but not for those beyond. This suggests that only objects capable of being manipulated are the objects capable of offering affordance in the eyes of an organism. In summary, our study suggests a novel definition of object-ness in an affordance-based context, advocating the concept of embodied cognition in understanding the emergence of intelligence constrained by an organism’s physical attributes.
Plasma growth hormone pulses induce male-biased pulsatile chromatin opening and epigenetic regulation in adult mouse liver
Authors: Rampersaud Andy , Connerney Jeannette , Waxman David J
Published: October 2023

Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is understood about the fundamental underlying, GH pattern-dependent regulatory mechanisms. Here, DNase-I hypersensitivity site (DHS) analysis of liver chromatin accessibility in a cohort of 18 individual male mice established that the endogenous male rhythm of plasma GH pulse-stimulated liver STAT5 activation induces dynamic, repeated cycles of chromatin opening and closing at several thousand liver DHS and comprises a novel mechanism conferring male bias to liver chromatin accessibility. Strikingly, a single physiological replacement dose of GH given to hypophysectomized male mice restored, within 30 min, liver STAT5 activity and chromatin accessibility at 83% of the dynamic, pituitary hormone-dependent male-biased DHS. Sex-dependent transcription factor binding patterns and chromatin state analysis identified key genomic and epigenetic features distinguishing this dynamic, STAT5-driven mechanism of male-biased chromatin opening from a second GH-dependent mechanism operative at static male-biased DHS, which are constitutively open in male liver. Dynamic but not static male-biased DHS adopt a bivalent-like epigenetic state in female liver, as do static female-biased DHS in male liver, albeit using distinct repressive histone marks in each sex, namely, H3K9me3 at male-biased DHS in female liver and H3K27me3 at female-biased DHS in male liver. Moreover, sex-biased H3K36me3 marks are uniquely enriched at static sex-biased DHS, which may serve to keep these sex-dependent hepatocyte enhancers free of H3K27me3 repressive marks and thus constitutively open. Pulsatile chromatin opening stimulated by endogenous, physiological hormone pulses is thus one of two distinct GH-determined mechanisms for establishing widespread sex differences in hepatic chromatin accessibility and epigenetic regulation, both closely linked to sex-biased gene transcription and the sexual dimorphism of liver function.
Sorting of secretory proteins at the trans-Golgi network by human TGN46
Authors: Lujan Pablo , Garcia-Cabau Carla , Wakana Yuichi , Vera Lillo Javier , Rodilla-Ramírez Carmen , Sugiura Hideaki , Malhotra Vivek , Salvatella Xavier , Garcia-Parajo Maria F , Campelo Felix
Published: October 2023

Secretory proteins are sorted at the trans-Golgi network (TGN) for export into specific transport carriers. However, the molecular players involved in this fundamental process remain largely elusive. Here, we identified the human transmembrane protein TGN46 as a receptor for the export of secretory cargo protein PAUF in CARTS – a class of protein kinase D-dependent TGN-to-plasma membrane carriers. We show that TGN46 is necessary for cargo sorting and loading into nascent carriers at the TGN. By combining quantitative fluorescence microscopy and mutagenesis approaches, we further discovered that the lumenal domain of TGN46 encodes for its cargo sorting function. In summary, our results define a cellular function of TGN46 in sorting secretory proteins for export from the TGN.
Toolkits for detailed and high-throughput interrogation of synapses in C. elegans
Authors: Majeed Maryam , Han Haejun , Zhang Keren , Cao Wen Xi , Liao Chien-Po , Hobert Oliver , Lu Hang
Published: October 2023

Visualizing synaptic connectivity has traditionally relied on time-consuming electron microscopy-based imaging approaches. To scale the analysis of synaptic connectivity, fluorescent protein-based techniques have been established, ranging from the labeling of specific pre- or postsynaptic components of chemical or electrical synapses to transsynaptic proximity labeling technology such as GRASP and iBLINC. In this paper, we describe WormPsyQi, a generalizable image analysis pipeline that automatically quantifies synaptically localized fluorescent signals in a high-throughput and robust manner, with reduced human bias. We also present a resource of 30 transgenic strains that label chemical or electrical synapses throughout the nervous system of the nematode
C. elegans
, using CLA-1, RAB-3, GRASP (chemical synapses), or innexin (electrical synapse) reporters. We show that WormPsyQi captures synaptic structures in spite of substantial heterogeneity in neurite morphology, fluorescence signal, and imaging parameters. We use these toolkits to quantify multiple obvious and subtle features of synapses - such as number, size, intensity, and spatial distribution of synapses - in datasets spanning various regions of the nervous system, developmental stages, and sexes. Although the pipeline is described in the context of synapses, it may be utilized for other ‘punctate’ signals, such as fluorescently-tagged neurotransmitter receptors and cell adhesion molecules, as well as proteins in other subcellular contexts. By overcoming constraints on time, sample size, cell morphology, and phenotypic space, this work represents a powerful resource for further analysis of synapse biology in
C. elegans
.
Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis
Authors: Homan Kentaro , Onodera Tomohiro , Hanamatsu Hisatoshi , Furukawa Jun-ichi , Momma Daisuke , Matsuoka Masatake , Iwasaki Norimasa
Published: October 2023

This study aimed to investigate the glycan structural changes that occur before histological degeneration in osteoarthritis (OA) and to determine the mechanism by which these glycan conformational changes affect cartilage degeneration. An OA model was established in rabbits using mannosidase injection, which reduced high-mannose type N-glycans and led to cartilage degeneration. Further analysis of glycome in human OA cartilage identified specific corefucosylated N-glycan expression patterns. Inhibition of N-glycan corefucosylation in mice resulted in unrecoverable cartilage degeneration, while cartilage-specific blocking of corefucosylation led to accelerated development of aging-associated and instability-induced OA models. We conclude that α1,6 fucosyltransferase is required postnatally to prevent preosteoarthritic deterioration of articular cartilage. These findings provide a novel definition of early OA and identify glyco-phenotypes of OA cartilage, which may distinguish individuals at higher risk of progression.
Multıfaceted Educatıonal Needs of Prımary School Students Movıng to Istanbul Due to Earthquake
Authors: Sözen Nurhüda
Published: October 2023

This study seeks to reveal the multifaceted educational needs of primary school students who left their hometown due to the earthquake and continue their education in Istanbul. The research was carried out with 35 classroom teachers teaching primary school students forced to leave their city due to the earthquake that occurred in Kahramanmaraş and continue their education in public schools in Istanbul. In this qualitative research, a semi-structured interview form prepared by the researcher was used as a data collection tool. The data were analyzed via the descriptive method. Within the scope of the research, findings related to the educational needs of the earthquake survivor primary school students, the role of the classroom teachers in the classroom climate in the context of the earthquake experience, the support training needs of the classroom teachers regarding the education of the earthquake survivor students, the teacher guidance for the well-being of the earthquake survivors’ parents, and the teachers’ expectations from different ministries under the theme of the earthquake were determined. As a result, suggestions were offered on various activities that education stakeholders can do to minimize or eliminate the effects of the trauma experienced by primary school students due to the earthquake.
Effect of Frostig Visual Perception Training Program on Visual Perception Skills of First Graders
Authors: Basak Rasim , Yaman Semra
Published: October 2023

The study aimed to examine effectiveness of a visual perception training program upon an application period of 14 weeks on primary school first graders. Effects of the Frostig Visual Perception Training Program were evaluated within demographics of gender, age, parental education level, previous kindergarten attainment and family income. The sample group consisted of first graders between the ages of 5-7 at a public primary school in Bursa, Türkiye. The study as an experimental model was designed based on screening-model sampling and conducted in the 2017-2018 academic year. Upon Pretest application of the visual perception instrument, Frostig Visual Perception Training Program was administered to the Treatment group once a week as part of art classes during 14 weeks. Visual perception skills of children were measured before and after training to examine, analyze and evaluate the developmental capacities and scope of children’s visual perception. While there was no significant difference between the Treatment and Control groups at the beginning, Post-test results showed a significant difference between cohorts upon training and utilization of the Frostig Visual Perception Training Program. Results were also compared based on various demographics. It was conclusively supported by the findings that the Frostig Visual Perception Training Program contributed to the children’s visual perceptive abilities positively. It was also concluded that visual perception development may contribute to children’s development to support early literacy-skill development. Therefore, art classes may play a central role especially for preschool and early grade levels.
Neo-classical Etude for Flute Solo: Evaluation of Karg Elert “op.107 no.30 Chaconne” in Terms of Technique and Pedagogy
Authors: Çenberci Senim , Gündüz Julide
Published: October 2023

Sigfrid Karg-Elert, one of the German organ composers of the 20th century, introduced the etudes titled 30 Caprices for Flute Solo Op. 107 into the flute education repertoire to meet the technical demands of the period’s orchestral music and flute repertoire. Among these etudes, no.30 Chaconne is a concert etude combining elements that require advanced technique with musical expression and style. This research, which aims to examine Karg-Elert’s op.107 no.30 Chaconne etude in terms of form, technique, and pedagogy, is a descriptive case study. A general form analysis of Chaconne was made in the first dimension of the research. Chaconne was examined from a technical perspective in the second dimension of the study. The techniques included in the etude are categorized as articulation technique, finger technique, sonority/embouchure technique, and ornaments. The techniques’ usage rates in the etude are determined by frequency and percentages. Among the various articulation techniques included in the etude, the legato technique has the highest usage rate, with 42.10%, and among the fingering techniques, chromatic scales had the highest at 30.26%. In sonority techniques, the usage rate of wide intervals of octave and above is very high at 39.47%. In this context, it has been determined that the most decisive difficulty in the etude comes from the use of wide intervals, and it has been concluded that a significant level of flexibility and embouchure control must be provided in the performance of the etude. The technical difficulties included in the etude were determined on a variation basis in the last dimension of the study, and a study guide consisting of original exercise suggestions was presented. This study is novel in the literature as it presents a study guide on Chaconne. Also, this study is thought to contribute to musical literacy by enabling performers to comprehend Karg Elert Chaconne multi-dimensionally.
Teacher! Please Light My Way: Effect of Providing Individual Feedback on Achievement in Social Studies Education
Authors: Akpinar Mehmet , Özalp M. Talha
Published: October 2023

Feedback in education is messages that contain information about how close the student’s current behavior in the learning process is to the expected behavior, what deficiencies and mistakes exist, and how they can be eliminated, and messages that contain information about the last level reached. Feedback guides students’ learning and is an important component of assessment. In this study, the type of individual feedback was discussed. The research aims to determine the effect of the individual feedback provided to the students from the social studies course on their exam success. The research was conducted with three different social studies teachers and their six different students at three different socio-economic levels. After the teachers were given effective feedback training, two students in their classes were asked to give individual feedback on their lessons. At the end of the process, the exam scores of the students before receiving feedback and the exam scores after receiving feedback were compared according to the class averages. In addition, the opinions of the teachers in this process were also taken in the research. As a result of the research, it was determined that the exam scores of the students who received individual feedback increased and there was a higher change in their scores compared to the class average. According to the teachers, individual feedback increased the students’ interest in the lesson. Finally, teachers suggested to their colleagues that they should receive training on feedback and emphasized that every teacher should be good feedback literacy. Based on these results of the study, it is suggested that teachers should be trained about feedback and that their feedback literacy levels should be increased.
A Systematic Review of Instructional Interventions Applied to Primary School Students with Mathematics Learning Difficulties
Authors: Filiz Tunahan , Güneş Gönül
Published: October 2023

This study was undertaken to systematically analyze instructional interventions employed to enhance the mathematical performance of elementary school students with Math learning difficulties (MLD). Over 20 years (2003-2023), 34 articles that met the inclusion criteria were included in the analysis. The articles in the study were analyzed in terms of methodological and intervention characteristics. Methodological characteristics were analyzed in two categories: participant characteristics and tests for identifying students. Intervention characteristics were analyzed in six categories: grade level, instructional intervention, implementer, implementation method, intervention duration, and mathematics learning area. It was found that the articles examined generally targeted students with MLD, and standardized achievement tests were used to identify students. The articles reviewed determined that third grade students were studied as participant students and strategy teaching was frequently used as an intervention programme. In the reviewed studies, the instructional interventions applied to students with math learning difficulties were implemented mainly by expert implementers in small-group teaching. It was observed that the number of sessions for instructional interventions ranged from 4 sessions to 96 sessions, with an average intervention duration of 16.91 hours. Finally, it was determined that the instructional interventions in the analyzed studies mainly focused on the learning domain of numbers and operations as the mathematics learning area.
Relationships between Digital Reading Motivation, Turkish Lesson Attitude, Reading Anxiety and Reading Comprehension of Fourth Grade Primary School Students
Authors: Bakkaloglu Selva
Published: October 2023

The aim of this study is to examine the relationship between reading anxiety, digital reading motivation, Turkish lesson attitude and reading comprehension levels of fourth grade primary school students. The design of the research is relational research model. The study group consists of 123 students studying in the fourth grade of primary school. Digital reading motivation scale, reading anxiety scale, Turkish lesson attitude scale and reading comprehension tests were used as data collection tools. SPSS 26 program was used in the analysis of the data. According to the results of the research; there is a significant negative relationship between reading anxiety and reading comprehension and a significant positive relationship between Turkish lesson attitude and digital reading motivation. There is no significant relationship between Turkish lesson attitude and reading comprehension and between digital reading motivation and reading comprehension. Relational analyses can be expanded by studying the psychological factors that affect students’ reading with different study groups. Thus, arrangements can be made to improve students’ reading regardless of grade level.
A History Lesson Designed with the Digital Storytelling Method: Kara Fatma Example
Authors: Özdemir Kamuran , Tuna Yasemin Er
Published: October 2023

Due to the reflections of the changes and developments in science and technology in the field of education, students need educational opportunities that can meet their changing learning needs. Based on this need, the main purpose of this study is to evaluate the digital storytelling process in history teaching and the contribution of this method to history teaching through the views of students. To achieve this goal, a history lesson about “Kara Fatma”, one of the heroines of the National Struggle in the 12th Grade Turkish Republic History of Revolution and Kemalism course, was designed using the digital storytelling method. A seven-week-long study was planned. The qualitative research method was used in the study. The study group consisted of 15 volunteer 12th-grade students. A semi-structured interview form was used to determine the evaluations of the students about the digital storytelling process, and a checklist was employed to evaluate students’ digital stories. The study data were analyzed with content analysis. As a result, it was found that students only used internet sources during the evidence search process, their knowledge of history was enriched with digital storytelling, and that they had difficulty eliciting material for their stories from a huge stack of information. It was concluded that this application contributed to making history lessons fun and could contribute to the presentation of brief and concise, but not long and boring, information and the use of critical thinking skills in lessons. Thus, it has been understood that digital storytelling may contribute to the development of historical literacy in students.
Determining the Levels of Writing Travel Articles of Secondary School 7th Grade Students
Authors: Şaşmaz Emel , Çifci Selcen
Published: October 2023

In this study, it was aimed to develop a rubric to determine the travel writing levels of secondary school 7th grade students and to determine the students› travel writing skill levels. The descriptive scanning design of the quantitative model was adopted. It was decided to develop an analytical rubric because it serves to measure the sub-skills of each skill and can be presented as feedback to the students. The rubric consists of three dimensions: layout, spelling, and punctuation, language and expression, and 18 items. It consists of 4 levels 1 (improved), 2 (moderate), 3 (good), and 4 (very good). The study group of the research consists of 114 7th grade students. The students in the study group were asked to write a travel writing text in one class hour and the travel writings were evaluated by two experts using the travel writing rubric. The collected data were analyzed using the descriptive analysis technique. As a result of the research, it was determined that most of the students were at a good level in using titles, including observations and impressions, commenting on the places visited, giving place to their memories about the trip, and making descriptions and coherent writing in their travel writings. In addition, it was determined that the students did not compare the places they visited and the places they lived in their travel writings in terms of place and society, did not give information about the geographical and historical characteristics of the place visited, and did not talk about the traditions and customs of the place visited.
Effect of using Culture-Themed Documentaries on Guided Writing Skills in Teaching Turkish to Foreigners
Authors: Özçelik Mine , Batur Zekerya
Published: October 2023

The present study aimed to determine whether using culture-themed documentaries in Turkish teaching of B2 level international students has effects on the development of guided writing skills. The study had an action-research design, which is one of the qualitative study approaches. The study group consisted of 12 international students at the B2 level who learned Turkish in the 2022-2023 academic year at the Turkish Teaching Application and Research Center of a state university in Turkey. The data collection process was performed under two headings as “developing an action plan” and “implementing the action plan”. During the developing an action plan stage, the themes and documentaries to be used in the activities were determined by receiving the opinions of the experts. In the next step, guided writing activities were prepared in line with the writing acquisitions by consulting experts. The pilot applications of the activities were performed at the Turkish Teaching Application and Research Center of a state university in Turkey. Quantitative and qualitative data collection tools were used and the developmental status of the students was monitored to interpret how the guided writing skill activities developed in the classroom environment progressed. The worksheets of the students were evaluated by using the “Guided Writing Scoring Key”, which was developed by the researchers. Students’ pre-test, application order, post-test, and permanency scores were determined with this key. Based on the findings obtained in the study, it was concluded that using culture-themed documentaries in Turkish teaching of international students improved the guided writing skill levels of the students.
Population genetic structure and hybrid zone analyses for species delimitation in the Japanese toad (Bufo japonicus)
Authors: Fukutani Kazumi , Matsui Masafumi , Nishikawa Kanto
Published: October 2023

Hybridization following secondary contact may produce different outcomes depending on the extent to which genetic diversity and reproductive barriers have accumulated during isolation. The Japanese toad,Bufo japonicus, is distributed on the main islands of Japan. In the present study, we applied multiplexed inter-simple sequence repeat genotyping by sequencing to achieve the fine-scale resolution of the genetic cluster inB. j. japonicusandB. j. formosus. We also elucidated hybridization patterns and gene flow degrees across contact zones between the clusters identified. Using SNP data, we found four genetic clusters inB. j. japonicusandB. j. formosusand three contact zones of the cluster pairs among these four clusters. The two oldest diverged lineages,B. j. japonicusandB. j. formosus, formed a narrow contact zone consistent with species distinctiveness. Therefore, we recommend that these two subspecies be elevated to the species level. In contrast, the less diverged pairs of two clusters inB. j. japonicusandB. j. formosus, respectively, admixed over a hundred kilometers, suggesting that they have not yet developed strong reproductive isolation and need to be treated as conspecifics. These results will contribute to resolving taxonomic confusion in Japanese toads.
Before Repairing: Pausing and Knotting Discomfort
Authors: Pérez-Bustos Tania , Botero Andrea
Published: October 2023

In this work, we reflect on a speculative pedagogical exercise in which we recorded, and invited others to record, through and with knots, situations of our daily lives related to forms of containment and entrapment. Accompanying this creative and collaborative work allowed us to materialize situations of vulnerability and unease (as knots), as well as the difficulty of registering these discomforts (through knots). We are interested in presenting this exercise as an embodied design practice. We also want to highlight how the staging of vulnerability and unease―made through material practices― generates contemplative pauses that have the power to make the fragility of life visible, and thus anticipate the need for repair. We argue here that repair, as a practice linked to design, is a making that deserves to be propitiated by contemplation and catharsis, in the face of damage and fragility in capitalist contexts.
Circles and Mistakes: Interview with Tim Ingold
Authors: Ingold Tim , Callén Blanca , Duque Melisa
Published: October 2023

Tim Ingold is a British anthropologist, Social Anthro­pology Professor at the University of Aberdeen, Fellow of the British Academy, and Fellow of the Royal Society of Edinburgh. He has explored the relationship between anthropology, architecture, art, and design; and through his work, has invited us to ‘think through making’ and ‘learn by doing’. Ingold is the author of Evolution and Social Life (Cam­bridge University Press, 1986); Lines: A Brief History (Routledge, 2007); Making: Anthropology, Archaeology, Art and Architecture (Routledge, 2010); and Anthropol­ogy: Why it Matters (Polity, 2018), among many other books. In this interview he responds to some questions about the practice of repair in his own daily life, but also the role and comprehension of repair in his intellectual work, and the possible connection between such action and the act of design.
Components of intellectual capital for the research process in higher education institutions
Authors: Tovar Carlos Vidal , Tejedor Gerardo González , Hernández Yimy Gordon , Santamaria Martha Padilla , Fuentes Harold Valle
Published: October 2023

The intellectual support variables used within the investigative process in Higher Education Institutions were characterized. Research with a quantitative, positivist, analytical approach, field designs, in a non-experimental, transversal or transactional way, descriptive type. The study population group is made up of vice-rectories of the research area, coordinations, headquarters or leaders of the research area, who are in charge of the management and viability of the research processes in 7 universities of Cartagena de Indias, survey, an instrument was used with alternatives of closed Likert-type answers, the Statistics of the data was Descriptive systematized in Microsoft Excel, SPSS and R.3.2.3. It is allowed to show that there is not a sufficient amount of economic resources available to carry out research, Relationships with both companies and other government institutions must be strengthened to develop investigative processes that entail producing intellectual material. As well as implementing methodologies to increase and strengthen knowledge networks; as well as virtual repositories.
Electrochemical Additive Manufacturing of Living Bioelectrodes Having Intimate Electronic Couplings between Exoelectrogens and Electrodes
Authors: Elhadad Anwar , Choi Seokheun
Published: October 2023

Engineered living materials (ELMs) combine living organisms with nonliving components to create responsive functions, improving traditional materials and devices. By incorporating electrochemically active microorganisms into a redox‐active matrix, ELMs merge microbial processes with environmental cleaning and sustainable energy on a scalable level. This technology faces challenges in merging the living and nonliving, and ensuring consistent manufacturing. The research introduces highly efficient living bioelectrodes, made using advanced biomanufacturing and a special 3D printing process with a microbe‐infused ink. A custom 3D printer with electropolymerization creates these organic bioelectrodes without templates, marking a significant advancement in ELM technology. The material used, poly(3,4‐ethylenedioxythiophene), is key for electron transfer between the active microorganisms and external systems without harming bacterial function. The ELM structure allows light and gas permeability and maintains thermal gradients, promising major innovations in bioelectronics, bioenergy, and biosensors.
Tiny Windows in Reticular Nanomaterials for Molecular Sieving Gas Separation Membranes
Authors: Smirnova Oksana , Ojha Subham , De Ankita , Schneemann Andreas , Haase Frederik , Knebel Alexander
Published: October 2023

The current state of reticular chemistry enables the synthesis of a wide range of highly porous nanomaterials for gas separation, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), porous organic cages (POCs), metal‐organic cages (MOCs), and polyhedra (MOPs). This perspective focuses on membrane technology, a key player in energy‐efficient gas separations. It explores the world of reticular materials, taking a glance at tiny pore windows with narrow openings, which are ideal for high‐resolution molecular sieving, and how to design them. Promising concepts in this field are membranes consisting of neat materials, but also mixed matrix membranes, where polymeric films incorporate reticular fillers, creating cost‐efficient membranes. This article sheds light on the potential use of reticular materials as membrane components. The reticular synthesis of MOFs offers the ability to separate gas molecules with minimal size differences effectively. For COFs, the crucial factor lies in reducing their pore size, preferably through functional group modifications. Porous cage compounds can achieve fine distribution from homogeneous dispersions into polymers making them excellent candidates for mixed matrix membranes. This perspective provides strategies and guiding principles for the future of reticular nanomaterials‐based membranes, addressing the pressing need for advanced and efficient separation technologies.
Controlling the Water Diffusion Inside Smart 4D‐Printed HBC by Functional Channels
Authors: Fruleux Thomas , Correa David , Castro Mickael , Poppinga Simon , Wang Kui , Le Duigou Antoine
Published: October 2023

Hydromorph Biocomposites (HBCs) are self‐shaping materials whose motions are actuated by moisture‐induced swelling of natural fibers and designed through a multilayered bioinspired material architecture. Their reactivity, i.e., kinetic of actuation, is relatively slow and is currently limited by the moisture transport. Porosities are commonly assumed to be a defect in composite materials that results in reduced mechanical performance. However, in biological structures porosities within the tissue architecture provide essential functions (lightness, moisture transport, and actuation). Inspired by biological mesostructures, a 3D‐printing process is applied to precisely define the architecture of an HBC that incorporates functional porosities, i.e., channels. The purpose is to improve the moisture‐induced actuation reactivity without compromising any other functional performance. First, 3D‐printed wood fiber‐reinforced biocomposites are designed with various channel content (from 0% to 10%), size (from 0.5 to 3.0 mm), and distribution patterns across the samples. Immersed in water, these novel HBCs with tailored channel structures fasten the water transport by triggering capillary transport. The presented results demonstrate that implementing functional channels in the mesostructure of 4D‐printed HBC bilayers makes it possible to achieve an eight‐fold improvement in the speed of shape‐change transformation while enabling new capabilities to functionally tune the morphing performance of HBCs.