bluuebunny/crossref_metadata_2025 huggingface dataset:
The Possibilities of Preservation, Regeneration and Presentation of Industrial Heritage: The Case of Old Mint “A.D.” on Belgrade Riverfront
Authors: Nikolić Marko , Drobnjak Boško , Kuletin Ćulafić Irena
Published: June 2020

This paper aims to explore industrial heritage of Belgrade that is located in the city center and therefore, has considerable potential for future architectural and urban development of the Serbian capital. The whole Belgrade riverfront area along the Sava and the Danube Rivers has a large number of abandoned industrial buildings that have significant value and need to be preserved and revitalized. This paper represents a research project conducted by lecturers at the Faculty of Architecture in Belgrade in the course History and Theory 1—Visual Culture in Architectural Theory and Practice. In order to provide productive research, we have employed the case study method based on the old Mint “A.D.”, which we have chosen as a characteristic example of Belgrade’s industrial heritage architecture. An important goal of this research is to provide professional information and raise public awareness about the importance and potential of industrial heritage for the future economic, cultural, social and tourist development of the city. This paper analyzes possibilities to comprehend the problems of the city’s industrial heritage protection regarding its historical and urban context, its genesis, authenticity, identity, cultural, architectural, economic, social, productive, creative and environmental values. According to that, the main goal of this research is concentrated on the sustainable preservation of specific cultural tangible and intangible values, spirit of the place, city identity and historic cityscape values that characterize industrial heritage in the social, cultural, natural and built environmental systems.
Influences of Behavioral Intention to Engage in Environmental Accounting Practices for Corporate Sustainability: Managerial Perspectives from a Developing Country
Authors: Chen Xiaofang , Weerathunga P.R. , Nurunnabi Mohammad , Kulathunga K.M.M.C.B. , Samarathunga W.H.M.S.
Published: June 2020

Environmental degradation is a serious global issue that has received increasing attention from scholars, policymakers, regulators, environmental activists, and the public as a whole. In the meantime, corporations have been criticized as major contributors to environmental pollution. Environmental accounting (EA) is a corporate practice that seeks to account for the cost of environmental impacts of business operations. However, it is questionable whether the true cost of environmental impacts of business operations is accounted for in the conventional accounting systems. In order to shed more light on this issue, this study examines key drivers of managerial intention to engage in EA practices in Sri Lanka. We employ the theory of planned behavior to conceptualize the antecedents of managers’ intention to engage in EA practices. The results of the partial least square structural equation model (PLS-SEM) evaluation revealed that managers’ intention is significantly influenced by the attitudes towards EA practices, subjective norms, and perceived behavioral control. Our results also indicate that a larger proportion of the variance of perceived behavioral control is explained by the perceived cost and complexity, perceived regulatory pressure, and organizational environmental orientation. The findings of this study provide important theoretical and practical implications for scholars, managers, and policymakers.
Effect of Nitrogen Fertilizer on Soil CO2 Emission Depends on Crop Rotation Strategy
Authors: Kong Dejie , Liu Nana , Ren Chengjie , Li Huiying , Wang Weiyu , Li Na , Ren Guangxin , Feng Yongzhong , Yang Gaihe
Published: June 2020

Developing environmentally friendly and sustainable nitrogen (N) fertilizer management strategies is crucial in mitigating carbon dioxide (CO2) emission from soil. How N fertilizer management practices influence soil CO2 emission rates under different crop rotations remains unclear. The aim of this study was to assess the impact on soil CO2 emission and soil physicochemical properties of three N fertilizer treatments including traditional rate (TF), optimized rate (0.8TF), and no fertilizer (NF) under three different crop rotation treatments: wheat-fallow (WF), wheat-soybean (WS), and wheat-maize (WM) over two years in a field experiment in northwest China. The rates were 5.51, 5.60, and 5.97 μmol·m−2·s−1 of mean soil CO2 emission under the TF, 0.8TF, and NF treatments, respectively. Mean soil CO2 emission rates were 21.33 and 26.99% higher under the WM rotation compared with the WF and WS rotations, respectively. The WS rotation showed higher soil nutrient content and lower soil CO2 emissions, and reduced fertilizer application. Importantly, soil organic carbon (SOC) concentration in the topsoil can be maximized by including either a summer legume or a summer maize crop in winter wheat rotations, and by applying N fertilizer at the optimal rate. This may be particularly beneficial in the dryland cropping systems of northern China.
From Disposal to Technological Potential: Reuse of Polypropylene Waste from Industrial Containers as a Polystyrene Impact Modifier
Authors: Luna Carlos Bruno Barreto , Siqueira Danilo Diniz , Ferreira Eduardo da Silva Barbosa , Silva Wallisson Alves da , Nogueira Jessika Andrade dos Santos , Araújo Edcleide Maria
Published: June 2020

The practice of recycling over the years has been increasingly encouraged, with the aim being the manufacturing of materials that contribute to sustainable development. In light of this, the present work evaluated the potential of mixtures of polystyrene (PS)/recycled copolymer polypropylene (PPr), using styrene-(ethylene/butylene)-styrene (SEBS) as a compatibilizing agent. Initially, the mixtures were prepared in a co-rotational twin-screw extruder, and, afterwards, the extruded granules were molded by injection. The properties of torque rheometry, impact strength, tensile properties, differential scanning calorimetry (DSC), heat deflection temperature (HDT), and scanning electron microscopy (SEM) were evaluated. The formulation PS/PPr/SEBS (70/20/10 %wt.) demonstrated an increase in viscosity, corroborating with an increase of 123% and 227% in the elongation at break and impact strength, respectively, compared to neat PS. Though the elastic modulus and tensile strength suffered losses, the reduction was not drastic. Furthermore, the addition of a semi-crystalline recycled material in the amorphous matrix (PS) contributed to an increase in thermomechanical strength, as seen in the HDT. The morphology revealed that SEBS is effective in making PS/PPr mixtures compatible because the dispersed phase is well adhered to the PS matrix and promotes greater morphological stability. Thus, it is possible to add value to discarded material and reduce the costs of the final product, which can reduce pollution.
Territorial Clusters of Farmers’ Interest in Diversification in Poland: Geospatial Location and Characteristics
Authors: Kiryluk-Dryjska Ewa , Więckowska Barbara
Published: June 2020

With a gradual shift towards sustainable rural development, farm diversification has recently gained importance in EU policy. To increase the efficiency of policies aiming to support farm diversification, it is of crucial importance to know the factors motivating farmers to diversify. The purpose of this paper was to research spatial determinants of farm diversification in Poland by identifying and describing territorial clusters of rural areas (municipalities), in which farmers’ interest in diversification is above or below the national average. The Moran’s global spatial autocorrelation coefficient was used to test for spatial autocorrelation, while the local Moran’s statistic served to group together municipalities which exhibited a level of the frequency of applying for diversification support above/below the average value for the entire territory covered by the analysis. Furthermore, the clusters were described with the use of synthetic characteristics of the Polish agriculture and rural areas. The existence and characteristics of clusters suggest that the policy toward diversification in Poland favors areas of better developed agricultural structures. In clusters with structural disadvantages where diversification is most needed, the program’s performance has been very modest. However, our analysis also revealed the existence of outlier municipalities which demonstrated outstanding performance in applying for diversification funds despite structural disadvantages. These observations suggest that the farmers’ interest in diversification may be driven by a number of additional factors beyond a structural disadvantage alone.
ICT Integration into Science Education and Its Relationship to the Digital Gender Gap
Authors: Palomares-Ruiz Ascensión , Cebrián Antonio , López-Parra Emilio , García-Toledano Eduardo
Published: June 2020

The objective of the research is to know whether the use of technologies in the teaching of sciences, in the face of more traditional methods, influences gender differences, justifying the low enrolment of women in technical careers. The study was developed using a pretest–posttest quasi-experimental method through a nonequivalent control group with traditional methodology and common instruments such as the textbook, while in the experimental group, methodologies based on the management of ICT tools were made. We make a quantitative contrast of the impact on learning, considering the advantages and disadvantages of using technologies in science teaching, versus more traditional methods. The experimental group showed a higher motivation, being seen in the impact on better learning scores compared to the control group. We found that women scored higher than men in both pretest and posttest. We conclude by emphasizing the desirability of a transformation of science teaching methodologies by using ICT tools that allow more visual, intuitive, and collaborative work, with greater involvement of students.
Industry Performance Appraisal Using Improved MCDM for Next Generation of Taiwan
Authors: Lee Zon-Yau , Chu Mei-Tai , Wang Yu-Ting , Chen Kuan-Ju
Published: June 2020

It is critical for manufacturing sectors to improve maximum performance to foster a competitive advantage. This article aims to analyze how the manufacturing industry can promote its performance to achieve sustainable development. We embark performance evaluation on Taiwanese manufacturing sectors which have profound implications in the global manufacturing supply chain. This study collected public information and reliable data from the Industrial Technology Research Institute (ITRI) covering 12 Taiwanese manufacturing industries. Performance evaluation indicators consist of four inputs chosen from a set of six items, whereas one output is from a set of three items. The analysis from Data Envelopment Analysis (DEA) is conducted including CCR (Charnes, Cooper, & Rhodes) efficiency, BCC (Banker et al.) efficiency, A&P(Andersen and Petersen) efficiency, cross-efficiency and D&G(Doyle and Green) efficiency plus the VIKOR prioritization method to evaluate the 12 manufacturing industries in Taiwan. The comprehensive analysis and comparison results of this study show the sophisticated outcomes through the analysis of DEA and VIKOR. In another objective evaluation, the efficiency of DEA proves a certain correlation between the model and the measurement of the VIKOR method. The results indicate that Taiwan’s manufacturing industry is moving towards design innovation thinking towards the high value of its own brand, whereas the industries in China and South East Asia appear different. The results can provide the best practice to allow the international manufacturing industry to enjoy a resurgence after falling output and diminishing labor force.
Flood Risk Assessment in an Underground Railway System under the Impact of Climate Change—A Case Study of the Barcelona Metro
Authors: Forero-Ortiz Edwar , Martínez-Gomariz Eduardo , Cañas Porcuna Manuel , Locatelli Luca , Russo Beniamino
Published: June 2020

Flooding events can produce significant disturbances in underground transport systems within urban areas and lead to economic and technical consequences, which can be worsened by variations in the occurrence of climate extremes. Within the framework of the European project RESCCUE (RESilience to cope with Climate Change in Urban arEas—a multi-sectorial approach focusing on water), climate projections for the city of Barcelona manifest meaningful increases in maximum rainfall intensities for the 2100 horizon. A better comprehension of these impacts and their conditions is consequently needed. A hydrodynamic modelling process was carried out on Barcelona Metro Line 3, as it was identified as vulnerable to pluvial flooding events. The Metro line and all its components are simulated in the urban drainage models as a system of computational link and nodes reproducing the main physical characteristics like slopes and cross-sections when embedded in the current 1D/2D hydrodynamic model of Barcelona used in the project RESCCUE. This study presents a risk analysis focused on ensuring transport service continuity in flood events. The results reveal that two of the 26 stations on Metro Line 3 are exposed to a high risk of flooding in current rainfall conditions, and 11 of the 26 stations on Metro Line 3 are exposed to a high risk of flooding in future rainfall conditions for a 20-year return period event, which affects Metro service in terms of increased risk. This research gives insights for stakeholders and policymakers to enhance urban flood risk management, as a reasonable approach to tackle this issue for Metro systems worldwide. This study provides a baseline for assessing potential flood outcomes in Metro systems and can be used to evaluate adaptation measures’ effectiveness.
Towards a Tourism and Community-Development Framework: An African Perspective
Authors: Gohori Owen , van der Merwe Peet
Published: June 2020

This article examines the perceptions of local people concerning the potential of tourism to alleviate poverty and bring about community development in the Manicaland Province, Zimbabwe. In-depth interviews, direct observations, and informal conversations were used to collect data in the four districts of Manicaland where there were functional community-based tourism (CBT) projects. After establishing a poverty criterion, data were collected from 43 local poor people in the four districts of the case study area. The results show that tourism development in Manicaland brought about community development through social, economic, environmental and cultural benefits. The authors suggest that there are interrelationships between tourism, poverty alleviation and community development. They show these interrelationships through a tourism and community-development framework which they developed based upon the results of the various methods of data collection used in this study.
Relationship between Surface Properties and Fiber Network Parameters of Eucalyptus Kraft Pulps and Their Absorption Capacity
Authors: Azevedo Catarina A. , Rebola Sofia M. C. , Domingues Eddy M. , Figueiredo Filipe M. L. , Evtuguin Dmitry V.
Published: June 2020

Water absorption capacity is a key characteristic of cellulosic pulps used for different commodities. This property is influenced by the affinity of the pulp fiber surface with water, chemical composition of the pulp, morphology, and organization of fibers in the network. In this study, surface properties of six industrial Eucalyptus bleached kraft pulps (fluff pulps) dry-defiberized in a Hammermill, which were obtained by wood pulping and pulp bleaching under different production conditions, were studied while employing dynamic water vapor sorption and contact angles measurements. The absorption properties of air-laid pulp pads were analyzed following the absorbency testing procedure and the relationship between these properties and pulp’s chemical composition and fiber network structure were assessed by multivariate analysis. The results showed that the accessibility of the fiber surface is related to the reduction of the contact angles, but, at the same time, to the longer absorption time and less absorption capacity of the fiber network. Therefore, the absorption properties of the pulps are not necessarily directly related to their surface properties. Indeed, absorptivity is related to the surface chemical composition, fiber morphology, and fiber network structure. Thus, surface carboxylic groups promote total water uptake, resulting in better absorption capacity. Greater fiber coarseness and deformations (curl and kink) provide a less wettable surface, but a more porous network with higher specific volume, resulting in more absorbent air-laid formulations.
An Improved Near-field Magnetic Probe Radiation Profile Boundaries Assessment for Optimal Radiated Susceptibility Pre-Mapping
Authors: Merfeldas Audrius , Kuzas Pranas , Gailius Darius , Nakutis Zilvinas , Knyva Mindaugas , Valinevicius Algimantas , Andriukaitis Darius , Zilys Mindaugas , Navikas Dangirutis
Published: June 2020

In this paper, the near-field radiated susceptibility pre-mapping method is proposed using the improved near-field probe power radiation profile assessment. The modelling of the electromagnetic field strength in 80–3000 MHz range in the proximity of the near-field probe was performed. The −6 dB aperture boundaries of the near-field probe and their variation, due to the proximity of the radio frequency (RF) printed circuit board (PCB) components, were determined, while the aperture map distortion, arising from the proximity of the passive RF PCB components were evaluated. The scanning path requirements for the RF susceptibility mapping were determined. The simulation of improved near-field probe absolute magnetic field strength reference map in open-air conditions is carried out in this work. The comparative analysis using the absolute maximum difference metric of orthogonal absolute magnetic field map cross-sections between the reference map and magnetic field maps affected by the proximity of the components was carried out. The experimental study of the RF amplifier stage susceptibility map with susceptibility mapping measurement results are presented in this work.
Identification of Apple Tree Leaf Diseases Based on Deep Learning Models
Authors: Chao Xiaofei , Sun Guoying , Zhao Hongke , Li Min , He Dongjian
Published: June 2020

Early diagnosis and accurate identification of apple tree leaf diseases (ATLDs) can control the spread of infection, to reduce the use of chemical fertilizers and pesticides, improve the yield and quality of apple, and maintain the healthy development of apple cultivars. In order to improve the detection accuracy and efficiency, an early diagnosis method for ATLDs based on deep convolutional neural network (DCNN) is proposed. We first collect the images of apple tree leaves with and without diseases from both laboratories and cultivation fields, and establish dataset containing five common ATLDs and healthy leaves. The DCNN model proposed in this paper for ATLDs recognition combines DenseNet and Xception, using global average pooling instead of fully connected layers. We extract features by the proposed convolutional neural network then use a support vector machine to classify the apple leaf diseases. Including the proposed DCNN, several DCNNs are trained for ATLDs recognition. The proposed network achieves an overall accuracy of 98.82% in identifying the ATLDs, which is higher than Inception-v3, MobileNet, VGG-16, DenseNet-201, Xception, VGG-INCEP. Moreover, the proposed model has the fastest convergence rate, and a relatively small number of parameters and high robustness compared with the mentioned models. This research indicates that the proposed deep learning model provides a better solution for ATLDs control. It could be also integrated into smart apple cultivation systems.
Intuitionistic Fuzzy Three-Way Decision Model Based on the Three-Way Granular Computing Method
Authors: Xin Xianwei , Song Jihua , Peng Weiming
Published: June 2020

Three-way decisions, as a general model for uncertain information processing and decisions, mainly utilize the threshold generated by the decision cost matrix to determine the decision category of the object. However, the determination of the threshold is usually accompanied by varying degrees of subjectivity. In addition, the potential symmetrical relationship between the advantages and disadvantages of the decision cost is also a problem worthy of attention. In this study, we propose a novel intuitionistic fuzzy three-way decision (IFTWD) model based on a three-way granular computing method. First, we present the calculation methods for the possibility of membership state and non-membership state, as well as prove the related properties. Furthermore, we investigate the object information granules, i.e., the fine-grained, medium-grained, and coarse-grained objects, by combining the state probability distribution and probability distribution. Then, for decision and evaluation issues, we define the superiority-compatibility relation and inferiority-compatibility relation for IFTWD model construction. In addition, we use the superiority degree and inferiority degree instead of the original thresholds and design a new method for evaluating decision cost. Finally, we focus on the algorithm research of the proposed model and present an empirical study of agricultural ecological investment in Hubei Province to demonstrate the effectiveness of our model.
A New Quasi Cubic Rational System with Two Parameters
Authors: Tuo Ming-Xiu , Zhang Gui-Cang , Wang Kai
Published: June 2020

The purpose of this article is to develop a new system for the construction of curves and surfaces. Making the new system not only has excellent properties of the orthodox Bézier and the B-spline method but also has practical properties such as variation diminishing and local shape adjustability. First, a new set of the quasi-cubic rational (QCR) system with two parameters is given, which is verified on an optimal normalized totally positive system (B-system). The related QCR Bézier curve is defined, and the de Casteljau-type algorithm are given. Next, a group of non-uniform QCR B-spline system is shown based on the linear combination of the proposed QCR system, the relative properties of the B-spline system are analyzed. Then, the definition and properties of non-uniform QCR B-spline curves are discussed in detail. Finally, the proposed QCR system is extended to the triangular domain, which is called the quasi-cubic rational Bernstein-Bézier (QCR-BB) system, and its related definition and properties of patches are given at length. The experimental image obtained by using MATLAB shows that the newly constructed system has excellent properties such as symmetry, totally positive, and C 2 continuity, and its corresponding curve has the properties of local shape adjustability and C 2 continuity. These extended systems in the extended triangular domain have symmetry, linear independence, etc. Hence, the methods in this article are suitable for the modeling design of complex curves and surfaces.
Smoke Object Segmentation and the Dynamic Growth Feature Model for Video-Based Smoke Detection Systems
Authors: Islam Md Rashedul , Amiruzzaman Md , Nasim Shahriar , Shin Jungpil
Published: June 2020

This article concerns smoke detection in the early stages of a fire. Using the computer-aided system, the efficient and early detection of smoke may stop a massive fire incident. Without considering the multiple moving objects on background and smoke particles analysis (i.e., pattern recognition), smoke detection models show suboptimal performance. To address this, this paper proposes a hybrid smoke segmentation and an efficient symmetrical simulation model of dynamic smoke to extract a smoke growth feature based on temporal frames from a video. In this model, smoke is segmented from the multi-moving object on the complex background using the Gaussian’s Mixture Model (GMM) and HSV (hue-saturation-value) color segmentation to encounter the candidate smoke and non-smoke regions in the preprocessing stage. The preprocessed temporal frames with moving smoke are analyzed by the dynamic smoke growth analysis and spatial-temporal frame energy feature extraction model. In dynamic smoke growth analysis, the temporal frames are segmented in blocks and the smoke growth representations are formulated from corresponding blocks. Finally, the classifier was trained using the extracted features to classify and detect smoke using a Radial Basis Function (RBF) non-linear Gaussian kernel-based binary Support Vector Machine (SVM). For validating the proposed smoke detection model, multi-conditional video clips are used. The experimental results suggest that the proposed model outperforms state-of-the-art algorithms.
Wear Resistance and Titanium Adhesion of Cathodic Arc Deposited Multi-Component Coatings for Carbide End Mills at the Trochoidal Milling of Titanium Alloy
Authors: Volosova Marina , Fyodorov Sergey , Opleshin Stepan , Mosyanov Mikhail
Published: June 2020

The work was devoted to the study of the effectiveness of the application of multi-component coatings, TiN–Al/TiN, TiN–AlTiN/SiN, and CrTiN–AlTiN–AlTiCrN/SiN, obtained by cathodic arc deposition to increase the wear resistance of 6WH10F carbide end mills in trochoidal milling of titanium alloy. The surface morphology of the tool with coatings was studied using scanning electron microscopy, and surface roughness texture was estimated. Microhardness and elastic modulus of the coated carbide tool surface layer were determined by nanoindentation. The process of sticking titanium to the working surface of the tool and quantitative evaluation of end mill wear with multi-component coatings at the trochoidal strategy of milling titanium alloy was studied. The CrTiN–AlTiN–AlTiCrN/SiN coating showed the maximum value of the plasticity index at the level of 0.12. The maximum effect of reducing the wear rate was achieved when using a tool with a CrTiN –AlTiN–AlTiCrN/SiN coating when the operating time to failure of end mills was increased by 4.6 times compared to samples without coating, by 1.4 times compared with TiN–Al/TiN coating and 1.15 times compared with TiN–AlTiN/SiN coating.
Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane
Authors: Li Feng , Shrivastava Indira H. , Hanlon Paul , Dagda Ruben K. , Gasanoff Edward S.
Published: June 2020

Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via the formation of non-bilayer, immobilized phospholipids that are critical in modulating ATP-synthase activity. In this study, we investigated the effects of another cardiotoxin CTI from Naja oxiana cobra venom on the structure of mitochondrial membranes and on mitochondrial-derived ATP synthesis. By employing robust biophysical methods including 31P-NMR and 1H-NMR spectroscopy, we analyzed the effects of CTI and CTII on phospholipid packing and dynamics in model phosphatidylcholine (PC) membranes enriched with 2.5 and 5.0 mol% of cardiolipin (CL), a phospholipid composition that mimics that in the outer mitochondrial membrane (OMM). These experiments revealed that CTII converted a higher percentage of bilayer phospholipids to a non-bilayer and immobilized state and both cardiotoxins utilized CL and PC molecules to form non-bilayer structures. Furthermore, in order to gain further understanding on how cardiotoxins bind to mitochondrial membranes, we employed molecular dynamics (MD) and molecular docking simulations to investigate the molecular mechanisms by which CTII and CTI interactively bind with an in silico phospholipid membrane that models the composition similar to the OMM. In brief, MD studies suggest that CTII utilized the N-terminal region to embed the phospholipid bilayer more avidly in a horizontal orientation with respect to the lipid bilayer and thereby penetrate at a faster rate compared with CTI. Molecular dynamics along with the Autodock studies identified critical amino acid residues on the molecular surfaces of CTII and CTI that facilitated the long-range and short-range interactions of cardiotoxins with CL and PC. Based on our compiled data and our published findings, we provide a conceptual model that explains a molecular mechanism by which snake venom cardiotoxins, including CTI and CTII, interact with mitochondrial membranes to alter the mitochondrial membrane structure to either upregulate ATP-synthase activity or disrupt mitochondrial function.
Insecticidal Activity of Bacillus thuringiensis Proteins against Coleopteran Pests
Authors: Domínguez-Arrizabalaga Mikel , Villanueva Maite , Escriche Baltasar , Ancín-Azpilicueta Carmen , Caballero Primitivo
Published: June 2020

Bacillus thuringiensis is the most successful microbial insecticide agent and its proteins have been studied for many years due to its toxicity against insects mainly belonging to the orders Lepidoptera, Diptera and Coleoptera, which are pests of agro-forestry and medical-veterinary interest. However, studies on the interactions between this bacterium and the insect species classified in the order Coleoptera are more limited when compared to other insect orders. To date, 45 Cry proteins, 2 Cyt proteins, 11 Vip proteins, and 2 Sip proteins have been reported with activity against coleopteran species. A number of these proteins have been successfully used in some insecticidal formulations and in the construction of transgenic crops to provide protection against main beetle pests. In this review, we provide an update on the activity of Bt toxins against coleopteran insects, as well as specific information about the structure and mode of action of coleopteran Bt proteins.
Correlation Functions of Quantum Artin System
Authors: Babujian Hrachya , Poghossian Rubik , Savvidy George
Published: June 2020

It was conjectured by Maldacena, Shenker and Stanford that the classical chaos can be diagnosed in thermal quantum systems by using an out-of-time-order correlation function. The Artin dynamical system defined on the fundamental region of the modular group SL(2,Z) represents a well defined example of a highly chaotic dynamical system in its classical regime. We investigated the influence of the classical chaotic behaviour on the quantum–mechanical properties of the Artin system calculating the corresponding out-of-time-order thermal quantum–mechanical correlation functions. We demonstrated that the two- and four-point correlation functions of the Liouiville-like operators decay exponentially with temperature dependent exponents and that the square of the commutator of the Liouiville-like operators separated in time grows exponentially.
Combinatory Treatment with Oseltamivir and Itraconazole Targeting Both Virus and Host Factors in Influenza A Virus Infection
Authors: Schloer Sebastian , Goretzko Jonas , Pleschka Stephan , Ludwig Stephan , Rescher Ursula
Published: June 2020

Influenza virus infections and their associated morbidity and mortality are a major threat to global health. Vaccination is an effective influenza prevention measure; however, the effectiveness is challenged by the rapid changes in the influenza virus genome leading to viral adaptation. Emerging viral resistance to the neuraminidase inhibitor oseltamivir limits the treatment of acute influenza infections. Targeting influenza virus-host interactions is a new and emerging field, and therapies based on the combination of virus- and host-directed drugs might significantly improve treatment success. We therefore assessed the combined treatment with oseltamivir and the repurposed antifungal drug itraconazole on infection of polarized broncho-epithelial Calu-3 cells with pdm09 or Panama influenza A virus strains. We detected significantly stronger antiviral activities in the combined treatment compared to monotherapy with oseltamivir, permitting lower concentrations of the drug than required for the single treatments. Bliss independence drug interaction analysis indicated that both drugs acted independently of each other. The additional antiviral effect of itraconazole might safeguard patients infected with influenza virus strains with heightened oseltamivir resistance.
Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread
Authors: Realegeno Susan , Priyamvada Lalita , Kumar Amrita , Blackburn Jessica B. , Hartloge Claire , Puschnik Andreas S. , Sambhara Suryaprakash , Olson Victoria A. , Carette Jan E. , Lupashin Vladimir , Satheshkumar Panayampalli Subbian
Published: June 2020

Although orthopoxviruses (OPXV) are known to encode a majority of the genes required for replication in host cells, genome-wide genetic screens have revealed that several host pathways are indispensable for OPXV infection. Through a haploid genetic screen, we previously identified several host genes required for monkeypox virus (MPXV) infection, including the individual genes that form the conserved oligomeric Golgi (COG) complex. The COG complex is an eight-protein (COG1–COG8) vesicle tethering complex important for regulating membrane trafficking, glycosylation enzymes, and maintaining Golgi structure. In this study, we investigated the role of the COG complex in OPXV infection using cell lines with individual COG gene knockout (KO) mutations. COG KO cells infected with MPXV and vaccinia virus (VACV) produced small plaques and a lower virus yield compared to wild type (WT) cells. In cells where the KO phenotype was reversed using a rescue plasmid, the size of virus plaques increased demonstrating a direct link between the decrease in viral spread and the KO of COG genes. KO cells infected with VACV displayed lower levels of viral fusion and entry compared to WT suggesting that the COG complex is important for early events in OPXV infection. Additionally, fewer actin tails were observed in VACV-infected KO cells compared to WT. Since COG complex proteins are required for cellular trafficking of glycosylated membrane proteins, the disruption of this process due to lack of individual COG complex proteins may potentially impair the virus-cell interactions required for viral entry and egress. These data validate that the COG complex previously identified in our genetic screens plays a role in OPXV infection.
Amino Acid at Position 166 of NS2A in Japanese Encephalitis Virus (JEV) Is Associated with In Vitro Growth Characteristics of JEV
Authors: Tajima Shigeru , Taniguchi Satoshi , Nakayama Eri , Maeki Takahiro , Inagaki Takuya , Lim Chang-Kweng , Saijo Masayuki
Published: June 2020

We previously showed that the growth ability of the Japanese encephalitis virus (JEV) genotype V (GV) strain Muar is clearly lower than that of the genotype I (GI) JEV strain Mie/41/2002 in murine neuroblastoma cells. Here, we sought to identify the region in GV JEV that is involved in its low growth potential in cultured cells. An intertypic virus containing the NS1-3 region of Muar in the Mie/41/2002 backbone (NS1-3Muar) exhibited a markedly diminished growth ability in murine neuroblastoma cells. Moreover, the growth rate of a Muar NS2A-bearing intertypic virus (NS2AMuar) was also similar to that of Muar in these cells, indicating that NS2A of Muar is one of the regions responsible for the Muar-specific growth ability in murine neuroblastoma cells. Sequencing analysis of murine neuroblastoma Neuro-2a cell-adapted NS1-3Muar virus clones revealed that His-to-Tyr mutation at position 166 of NS2A (NS2A166) could rescue the low replication ability of NS1-3Muar in Neuro-2a cells. Notably, a virus harboring a Tyr-to-His substitution at NS2A166 (NS2AY166H) showed a decreased growth ability relative to that of the parental virus Mie/41/2002, whereas an NS2AMuar-based mutant virus, NS2AMuar-H166Y, showed a higher growth ability than NS2AMuar in Neuro-2a cells. Thus, these results indicate that the NS2A166 amino acid in JEV is critical for the growth and tissue tropism of JEV in vitro.
Surveillance for Borrelia spp. in Upland Game Birds in Pennsylvania, USA
Authors: Cleveland Christopher A. , Swanepoel Liandrie , Brown Justin D. , Casalena Mary Jo , Williams Lisa , Yabsley Michael J.
Published: June 2020

The Borrelia genus contains two major clades, the Lyme borreliosis group, which includes the causative agents of Lyme disease/borreliosis (B. burgdorferi sensu stricto and other related B. burgdorferi sensu lato genospecies), and the relapsing fever borreliosis group (B. hermsii, B. turicatae, and B. parkeri). Other unclassified reptile- and echidna-associated Borrelia spp. (i.e., B. turcica and ‘Candidatus Borrelia tachyglossi’, respectively) do not belong in either of these two groups. In North America, Borrelia spp. from both of the major clades are important pathogens of veterinary and public health concern. Lyme disease is of particular interest because the incidence in the northeastern United States continues to increase in both dogs and humans. Birds have a potentially important role in the ecology of Borrelia species because they are hosts for numerous tick vectors and competent hosts for various Borrelia spp. Our goal was to investigate the prevalence of Borrelia spp. in four free-living species of upland game birds in Pennsylvania, USA including wild turkey (Meleagris gallopavo), ruffed grouse (Bonasa umbellus), ring-necked pheasants (Phasianus colchicus), and American woodcock (Scolopax minor). We tested 205 tissue samples (bone marrow and/or spleen samples) from 169 individuals for Borrelia using a flagellin gene (flab) nested PCR, which amplifies all Borrelia species. We detected Borrelia DNA in 12% (24/205) of samples, the highest prevalence was in wild turkeys (16%; 5/31), followed by ruffed grouse (13%; 16/126) and American woodcock (3%; 1/35). All pheasants (n = 13) were negative. We sequenced amplicons from all positive game birds and all were B. burgdorferi sensu stricto. Our results support previous work indicating that certain species of upland game birds are commonly infected with Borrelia species, but unlike previous studies, we did not find any relapsing fever borreliae.
Large Scale Flood Risk Mapping in Data Scarce Environments: An Application for Romania
Authors: Albano Raffaele , Samela Caterina , Crăciun Iulia , Manfreda Salvatore , Adamowski Jan , Sole Aurelia , Sivertun Åke , Ozunu Alexandru
Published: June 2020

Large-scale flood risk assessment is essential in supporting national and global policies, emergency operations and land-use management. The present study proposes a cost-efficient method for the large-scale mapping of direct economic flood damage in data-scarce environments. The proposed framework consists of three main stages: (i) deriving a water depth map through a geomorphic method based on a supervised linear binary classification; (ii) generating an exposure land-use map developed from multi-spectral Landsat 8 satellite images using a machine-learning classification algorithm; and (iii) performing a flood damage assessment using a GIS tool, based on the vulnerability (depth–damage) curves method. The proposed integrated method was applied over the entire country of Romania (including minor order basins) for a 100-year return time at 30-m resolution. The results showed how the description of flood risk may especially benefit from the ability of the proposed cost-efficient model to carry out large-scale analyses in data-scarce environments. This approach may help in performing and updating risk assessments and management, taking into account the temporal and spatial changes in hazard, exposure, and vulnerability.
How Different Are Manometric, Gravimetric, and Automated Volumetric BMP Results?
Authors: Amodeo Corrado , Hafner Sasha D. , Teixeira Franco Rúben , Benbelkacem Hassen , Moretti Paul , Bayard Rémy , Buffière Pierre
Published: June 2020

The objectives of this study were to: (1) quantify differences in biochemical methane potential (BMP) measured using three measurement methods, including two popular methods (a commercial automated system (AMPTS II) and manual manometric) and one newer method (gravimetric), and (2) assess the importance of the mixing position in the measurement sequence. Powdered microcrystalline cellulose was used as the substrate in simultaneous tests. All methods gave similar results (<8% difference in the mean BMP) and were reasonably accurate (recovery of 80–86% of the theoretical maximum BMP). Manometric BMP values were consistently lower than gravimetric by 4–5%. Precision was lower for the automated method (relative standard deviation (RSD) of about 7%) than for the manual methods (RSD about 1–3%). Mixing after biogas measurement resulted in 3% higher BMP for both manual methods than mixing before, due to the lower measured CH4 production from blanks. This effect may be linked to a fraction of CH4 that remains dissolved or even as attached bubbles, and suggests that mixing before measurement is preferable. The automated volumetric and gravimetric methods (mode 2) gave very similar mean BMP values (1% different). However, kinetic analysis showed that methane production was faster with the automated volumetric method. This could come from an error in the estimation of the CH4 production rate for the automated method, or an increase in the degradation rate due to better mixing. Both automatic volumetric and manual gravimetric measurements met current validation criteria for mean cellulose BMP, but the RSD from the automated system exceeded the limit.
Managed Aquifer Recharge in Africa: Taking Stock and Looking Forward
Authors: Ebrahim Girma Y , Lautze Jonathan F. , Villholth Karen G.
Published: June 2020

Climatic variability and change result in unreliable and uncertain water availability and contribute to water insecurity in Africa, particularly in arid and semi-arid areas and where water storage infrastructure is limited. Managed aquifer recharge (MAR), which comprises purposeful recharge and storage of surface runoff and treated wastewater in aquifers, serves various purposes, of which a prominent one is to provide a means to mitigate adverse impact of climate variability. Despite clear scope for this technology in Africa, the prevalence and range of MAR experiences in Africa have not been extensively examined. The objective of this article is provide an overview of MAR progress in Africa and to inform the potential for future use of this approach in the continent. Information on MAR from 52 cases in Africa listed in the Global MAR Portal and collated from relevant literature was analyzed. Cases were classified according to 13 key characteristics including objective of the MAR project, technology applied, biophysical conditions, and technical and management challenges. Results of the review indicate that: (i) the extent of MAR practice in Africa is relatively limited, (ii) the main objective of MAR in Africa is to secure and augment water supply and balance variability in supply and demand, (iii) the surface spreading/infiltration method is the most common MAR method, (iv) surface water is the main water source for MAR, and (v) the total annual recharge volume is about 158 Mm3/year. MAR schemes exist in both urban and rural Africa, which exemplify the advancement of MAR implementation as well as its out scaling potential. Further, MAR schemes are most commonly found in areas of high inter-annual variability in water availability. If properly planned, implemented, managed, maintained and adapted to local conditions, MAR has large potential in securing water and increasing resilience in Africa. Ultimately, realizing the full potential of MAR in Africa will require undertaking hydrogeological and hydrological studies to determine feasibility of MAR, especially in geographic regions of high inter-annual climate variability and growing water demand. This, supported by increased research to gauge success of existing MAR projects and to address challenges, would help with future siting, design and implementation of MAR in Africa.
Structural Properties of the Static Armor during Formation and Reestablishment in Gravel-Bed Rivers
Authors: Wang Qiang , Pan Yunwen , Yang Kejun , Nie Ruihua
Published: June 2020

The formation and reestablishment of bed structural properties in the static armor layer is an important research subject. To address this issue, we conducted a series of static armor layer experiments in a laboratory flume that focused on formation and reestablishment. Through an automatic measurement system, we obtained a real-time bed load transport rate. The bed surface elevation at different flow intensities was obtained using a PTS (Photo Terrain Scanning) system. The results show that the formation and reestablishment of the bed load transport rate in the static armor layer increased from zero to its peak before decaying. The bed structure response was found to be highly dependent on the unevenness of the bed surface elevation. The bed surface elevation of a static armor layer in a laboratory flume is considered as a two-dimensional random field. In a two-dimensional random field, the changes in bed elevation are characterized using statistical parameters. Statistical parameters are evaluated from precise digital elevation models (DEMs) of bed surfaces. Experimental results provide the change of probability distribution functions (PDFs) and second-order structure functions of bed elevations between formation and reestablishment after breaking the static armor layer. By quantitatively analyzing the changes in these statistical parameters, we quantified the difference between the bed structure in the static armor layer formation and the new static armor layer formed after being broken. Thus, this finding reveals that the bed structure of the static armor layer formed by different flow intensities is different, and this difference can be quantified using statistical methods.
Governing Urban Water Conflict through Watershed Councils—A Public Policy Analysis Approach and Critique
Authors: Pacheco-Vega Raul
Published: June 2020

Cities face substantial water governance challenges, even more so when their activities are water-intensive, as global tourism is. As the lower-most level of government, municipalities face important challenges when dealing with water stress. Designing robust urban water policy thus may require us to challenge currently popular modes of governance by river basin councils, as predicated by the integrated water resources management (IWRM) paradigm. In this paper, I conduct a public policy analysis of a case study of intra-urban water conflict in the Mexican city of San Miguel de Allende (SMA), an extremely popular tourist destination with substantive water scarcity challenges. I draw insights from an application of the Institutional Grammar Tool, IGT (as proposed by Ostrom and Crawford) on a series of textual datasets derived from ethnographic, qualitative longitudinal field research, document analysis, and elite interviews with stakeholders to explain the reasons underlying community concerns about urban water supply which have derived in conflict in San Miguel de Allende and increasingly manifested over the past few years (2017–2020). My analysis suggests that to tackle growing intra-urban antagonism derived from increasing water insecurity in San Miguel de Allende, a more localized, micro-watershed approach might be more fruitful than a traditional river basin council strategy.