bluuebunny/crossref_metadata_2025 huggingface dataset:
Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH
Authors: Beiroth Femke , Koudelka Tomas , Overath Thorsten , Knight Stefan D , Tholey Andreas , Lindhorst Thisbe K
Published: July 2018

Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial for adhesion, colonization and infection. Following our earlier work, we have here designed and synthesized diazirine-functionalized mannosides as high-affinity FimH ligands and performed an extensive study on photo-crosslinking of the best ligand (mannoside3) with a series of model peptides and FimH. Notably, we have employed high-performance mass spectrometry to be able to detect radiation results with the highest possible accuracy. We are concluding from this study that photolabeling of FimH with sugar diazirines has only very limited success and cannot be regarded a facile approach for covalent modification of FimH.
Visibilidade comunicativa na internet: uma análise da fan page de Marcelo Freixo
Authors: Grijó Wesley Pereira , Gracian Ícaro
Published: July 2018

A partir da interface entre Comunicação e Política, o artigo aborda como a perspectiva da visibilidade é materializada na fan page do político Marcelo Freixo, levando em consideração os temas e a periodicidade com que é trabalhada cada postagem. Para essa finalidade, o estudo é de abordagem quanti-qualitativa e utiliza para coleta de dados as pesquisas bibliográfica e documental no ambiente da internet. No que concerne aos resultados, o agente político e sua assessoria realizam, em média, quatro publicações diárias na página oficial, agrupadas em cinco temáticas: promoção de ideias e projetos; ataques e respostas a adversários; divulgação de eventos; mobilização, engajamento e apoio; mensagens alheias à política. Nelas, verifica-se a tentativa de engajar e mobilizar os eleitores para que abracem as causas e ideias do político, aproveitando a projeção e manutenção da visibilidade conquistadas nas eleições também fora do período eleitoral.
Actuelles sur les liens entre psychologie individuelle et psychologie sociale
Authors: Baligand Pascale
Published: July 2018

Dans cet article, l’auteure part d’une recherche collective portant sur l’accès aux soins des patients étrangers ou considérés comme tels pour formuler ses propositions concernant l’apport de la psychanalyse à l’étude des phénomènes de discrimination. Une discussion est ouverte sur le statut de termes survenus lors d’entretiens qualitatifs réalisés auprès de soignants, que la psychologie sociale repère traditionnellement comme des stéréotypes et des préjugés. En s’appuyant sur les travaux de différents auteurs sur la thématique de la présentabilité (Freud, Kahn) et des figures (Lyotard, Didi-Huberman), l’auteure propose de considérer ces termes comme des figures comparables aux figures du travail du rêve, à la fois concrètes et imagées, composites, et mettant en œuvre différentes temporalités individuelles et collectives. Cette démarche permet de souligner l’intérêt de l’étude du registre de la présentation en même temps que celui de la représentation pour aborder la question des discriminations, ainsi que l’intérêt de la notion de figure pour réinterroger les liens entre psychologie individuelle et psychologie sociale avec la psychanalyse.
The Management of Negative Transferences and the Problem of Submission in the Psychoanalytic Clinic
Authors: Frehse Pereira Priscila , Kupermann Daniel , Signorelli Mila
Published: July 2018

À travers une généalogie du transfert négatif dans la trajectoire clinique de Sándor Ferenczi, nous abordons une dimension du maniement des transferts négatifs au-delà de l'interprétation, que nous considérons comme l’héritière du changement clinique qui a permis à Ferenczi de prendre en compte l'implication de l'analyste dans la clinique psychanalytique. Le concept d’identification à l’agresseur, chez Ferenczi, permet l’articulation au problème de la soumission dans la clinique psychanalytique, point central du maniement du transfert négatif des cas limites montrant la nécessité de l'élasticité de la technique psychanalytique.
Le maniement du transfert négatif et le problème de la soumission dans la clinique psychanalytique
Authors: Frehse Pereira Priscila , Kupermann Daniel , Signorelli Mila
Published: July 2018

À travers une généalogie du transfert négatif dans la trajectoire clinique de Sándor Ferenczi, nous abordons une dimension du maniement des transferts négatifs au-delà de l'interprétation, que nous considérons comme l’héritière du changement clinique qui a permis à Ferenczi de prendre en compte l'implication de l'analyste dans la clinique psychanalytique. Le concept d’identification à l’agresseur, chez Ferenczi, permet l’articulation au problème de la soumission dans la clinique psychanalytique, point central du maniement du transfert négatif des cas limites montrant la nécessité de l'élasticité de la technique psychanalytique.
La résurgence du sacré dans la postmodernité
Authors: Rabot Jean-Martin
Published: July 2018

Le sacré, en tant que dimension essentielle de l’expérience humaine, a été délaissé par la modernité et les idéaux des Lumières qui lui servaient de fondement, tels que le progrès, la raison, l’histoire. En faisant siens ces idéaux, une partie de la sociologie a parié soit sur la disparition du sacré soit sur son rapatriement vers l’individualisme, s’interdisant ainsi de penser la transcendance en rapport avec l’immanence et de saisir la charge émotionnelle et religieuse à l’œuvre dans de nombreuses manifestations de la postmodernité. Une autre partie de la sociologie s’est attachée à montrer l’obsolescence des idéaux modernes et à comprendre la spécificité de la postmodernité. C’est reconnaître l’immatériel au fondement de toute réalité et le sacré comme forme permanente de toute structuration sociale. De ce point de vue, les technologies du numérique contribuent à la résurgence du sacré dans la postmodernité et confortent le mystère et la mystique que l’on retrouve dans la formation et la consolidation de l’existence communautaire et collective.
Digital religion, the supermarket and the commons
Authors: Rähme Boris
Published: July 2018

L’objectif de cet article est de mettre en évidence une intersection entre la recherche sur les spiritualités contemporaines et la recherche dans le domaine de la religion numérique. Le concept de la production entre pairs basée sur les communs (“commons-based peer production”), développé dans les domaines des technologies numériques sociales et de la collaboration en réseau, offre une alternative à l’analogie largement utilisée du supermarché spirituel, là où il s’agit de décrire et d’expliquer l’éclectisme présent dans quelques spiritualités contemporaines.
La sacralité numérique et la mystique de la technologie
Authors: Souza Aguiar Carlos Eduardo
Published: July 2018

Cet article propose de comprendre la relation entre religion et Internet à partir d’une perspective non instrumentale sur les technologies. Les technologies numériques et en réseaux peuvent être comprises comme le réceptacle contemporain des imaginaires religieux, plutôt que comme des outils de prosélytisme ou d’annonce de la bonne nouvelle. Par le biais d’une approche archéologique des médias techniques, il est possible de dégager les temps profonds du numérique dévoilant une mystique technologique tributaire d’une matérialité technique spécifique, caractérisée par les réseaux sans fil et les dispositifs mobiles. En affinité avec la spiritualité New Age , il s’agit d’une mystique au sein de laquelle se renforce l’image d’un environnement réticulaire animiste caractérisé par un retour du paganisme.
Jurema : culte, religion et espace public
Authors: Pinto Clélia , Pereira Campos Zuleica Dantas , Joron Philippe
Published: July 2018

Dans cette étude, nous chercherons à comprendre comment les adeptes du culte de la Jurema (forme de religiosité afro-amérindienne) élaborent des constructions symboliques dans leur quête de légitimité. Nous verrons ainsi de quelle manière cette religiosité pratiquée dans le Nord-Est du Brésil est apparue et continue à se construire en ayant pour base symbolique les représentations ethnico-religieuses d’origine afro-amérindienne. Nous souhaitons ainsi saisir la façon dont cette religion organise son processus de popularisation, d’institutionnalisation et d’insertion dans l’espace public que représente l’agglomération de Recife, capitale de l’État de Pernambouc. Dans cette optique, nous considérons que sa principale revendication est la légitimation d’un statut reconnu en tant que religion autonome. De ce point de vue, il apparaît que le culte de la Jurema , qu’il soit pratiqué par des groupes indigènes ou des populations urbaines, s’inscrit dans un processus de transformation radicale. Face à un monde fluidifié, liquéfié et globalement connecté, la Jurema revendique la légitimité de son existence dans l’espace public et religieux au sein de la société brésilienne.
L’affaire Lula et l’action de l’imaginaire dans les grands médias brésiliens
Authors: Larangeira Álvaro Nunes , Prado Júnior Tarcis , Iacomini Júnior Franco , Cardoso Moisés , Florenzano Antonio Carlos P.
Published: July 2018

Les médias internationaux, aux tendances politico-idéologiques semblables à leurs homologues hégémoniques brésiliens – conservateurs et néolibéraux, du centre, de centre-droit et de droite – ont intentionnellement pris le parti de la condamnation de l’ancien président Luiz Inácio Lula da Silva, rendue en première instance en juillet de l’année dernière et ratifiée en deuxième instance en janvier de l’année en cours. Cet article vise à définir, à partir de la répercussion de la condamnation de Lula dans les médias internationaux, le principe de présomption de culpabilité qui prévaut dans l’imaginaire des grands médias brésiliens dans des situations de classe. La méthodologie utilisée consiste en une approche qualitative, et le corpus se compose de documents issus de la presse nationale et internationale.
Partial zeta values, Gross's tower of fields conjecture, and Gross–Stark units
Authors: Dasgupta Samit , Spieß Michael
Published: July 2018

We prove a conjecture of Gross regarding the “order of vanishing” of Stickelberger elements relative to an abelian tower of fields and give a cohomological construction of the conjectural Gross–Stark units. This is achieved by introducing an integral version of the Eisenstein cocycle.
Quality Assurance and Quality Control in the Global Trachoma Mapping Project
Authors: Solomon Anthony W. , Willis Rebecca , Pavluck Alexandre L. , Alemayehu Wondu , Bakhtiari Ana , Bovill Sarah , Chu Brian K. , Courtright Paul , Dejene Michael , Downs Philip , Flueckiger Rebecca M. , Haddad Danny , Hooper P. J. , Kalua Khumbo , Kebede Biruck , Kello Amir Bedri , Macleod Colin K. , McCullagh Siobhain , Millar Tom , Mpyet Caleb , Ngondi Jeremiah , Nwobi Benjamin , Olobio Nicholas , Onyebuchi Uwazoeke , Rotondo Lisa A. , Sarr Boubacar , Shafi Oumer , Sokana Oliver , West Sheila K. , Foster Allen , _ _
Published: July 2018

In collaboration with the health ministries that we serve and other partners, we set out to complete the multiple-country Global Trachoma Mapping Project. To maximize the accuracy and reliability of its outputs, we needed in-built, practical mechanisms for quality assurance and quality control. This article describes how those mechanisms were created and deployed. Using expert opinion, computer simulation, working groups, field trials, progressively accumulated in-project experience, and external evaluations, we developed 1) criteria for where and where not to undertake population-based prevalence surveys for trachoma; 2) three iterations of a standardized training and certification system for field teams; 3) a customized Android phone–based data collection app; 4) comprehensive support systems; and 5) a secure end-to-end pipeline for data upload, storage, cleaning by objective data managers, analysis, health ministry review and approval, and online display. We are now supporting peer-reviewed publication. Our experience shows that it is possible to quality control and quality assure prevalence surveys in such a way as to maximize comparability of prevalence estimates between countries and permit high-speed, high-fidelity data processing and storage, while protecting the interests of health ministries.
Coaching Residents in the Ambulatory Setting: Faculty Direct Observation and Resident Reflection
Authors: Graddy Ryan , Reynolds Stasia S. , Wright Scott M.
Published: July 2018

Background 

Direct observation can be valuable for learners' skill development in graduate medical education, but it is done infrequently. Information on how to optimize trainee learning from, and best practices of, direct observation interventions in the ambulatory setting is limited.

Objective 

We explored the impact of a focused outpatient direct observation and coaching intervention on internal medicine residents.

Methods 

Using a behavior checklist based on tenets of clinical excellence, 2 faculty preceptors observed outpatient primary care visits with 96% (46 of 48) of the internal medicine residents in 2017. Residents self-assessed their performance after the visit using the same checklist. Next, a focused coaching feedback session, emphasizing reflection, was structured to highlight areas of discrepancy between resident self-assessment and coach observation (blind spots), and residents were asked to identify goals for practice improvement.

Results 

Common blind spots in resident self-assessment related to collaborating with patients while using the electronic health record (48%, 21 of 44), hand washing (43%, 20 of 46), and asking thoughtful questions (40%, 18 of 45). At 1-month follow-up, 93% (43 of 46) of responding residents reported change in practice toward goals often or sometimes. All residents reported that the intervention felt comfortable, and 98% (45 of 46) noted that it helped them identify new behaviors to incorporate into clinical practice.

Conclusions 

Structured episodes of direct observation and coaching in the outpatient setting, with a behavior checklist, appear acceptable and useful for internal medicine residents' learning and development.
Spatiotemporal variability of light attenuation and net ecosystem metabolism in a back-barrier estuary
Authors: Ganju Neil K. , Testa Jeremy M. , Suttles Steven E. , Aretxabaleta Alfredo L.
Published: July 2018

Abstract. The light climate in back-barrier estuaries is a strong control on phytoplankton and submerged aquatic vegetation (SAV) growth, and ultimately net ecosystem metabolism. However, quantifying the spatiotemporal variability of light attenuation and net ecosystem metabolism over seasonal timescales is difficult due to sampling limitations and dynamic physical and biogeochemical processes. Differences in the dominant primary producer at a given location (e.g., phytoplankton versus SAV) can also determine diel variations in dissolved oxygen and associated ecosystem metabolism. Over a one year period we measured hydrodynamic properties, biogeochemical variables (fDOM, turbidity, chlorophyll-a fluorescence, dissolved oxygen), and photosynthetically active radiation (PAR) at multiple locations in Chincoteague Bay, Maryland/Virginia, USA, a shallow back-barrier estuary. We quantified light attenuation, net ecosystem metabolism, and timescales of variability for several water properties at paired channel-shoal sites along the longitudinal axis of the bay. The channelized sites, which were dominated by fine bed sediment, exhibited slightly higher light attenuation due to increased wind-wave sediment resuspension. Light attenuation due to fDOM was slightly higher in the northern portion of the bay, while attenuation due to chlorophyll-a was only relevant at one channelized site, proximal to nutrient and freshwater loading. Gross primary production and respiration were highest at the vegetated shoal sites, though enhanced production and respiration were also observed at one channelized, nutrient-enriched site. Production and respiration were nearly balanced throughout the year at all sites, but there was a tendency for net autotrophy at shoal sites, especially during periods of high SAV biomass. Shoal sites, where SAV was present, demonstrated a reduction in gross primary production (GPP) when light attenuation was highest, but GPP at adjacent shoal sites where phytoplankton were dominant was less sensitive to light attenuation. This study demonstrates how extensive continuous physical and biological measurements can help determine metabolic properties in a shallow estuary, including differences in metabolism and oxygen variability between SAV and phytoplankton-dominated habitats.
The Role of Bureaucracy in Democratic Governance in Nigeria: Relevance and Evidence from Akwa Ibom State (1999-2017)
Authors: Ita Victor E. , Titus David A.
Published: July 2018

The paper examined how bureaucracy, as the legitimate organ for the implementation of state policies and programmes, has enhanced democratic governance in Nigeria using Akwa Ibom State as a reference point. The paper attempted to analyze the interplay between the political concept of democracy and bureaucratic practice in the State. The basic assumption of the paper was that democratic governance can be enhanced through effective and efficient bureaucracy. Based on documentary analysis with a tinge of survey (interview) method, it was observed that bureaucracy in Akwa Ibom has shown reasonable evidence of involvement in the implementation of government policies and programmes towards the welfare of the citizenry in demonstration of good governance. Moreover, the paper noted that the State bureaucracy needed to be repositioned to tackle some negative tendencies such as poor attitude to work, improper postings and placement of employees to positions of responsibilities and corrupt practices among public officials. Given these findings, it was recommended, among others, that the principles of transparency, probity and accountability should be made paramount as a norm and in praxis within and without the State bureaucracy; that meritocracy should constitute the basis for recruitments/appointments and postings within the civil service. These would enhance the effectiveness and efficiency of the bureaucracy towards democratic governance.
The Effect of Guided Discovery Learning Model with Superitem Test on Students’ Problem-Solving Ability in Mathematics
Authors: Hulukati Evi , Zakiyah Siti , Rustam Ali
Published: July 2018

This experimental study aims to compare problem-solving abilities between students that are taught with guided discovery learning models and conventional learning models. This study involved all eighth graders as the research population. Furthermore, the sampling technique used is the simple random sampling technique in two classes in Junior High school SMPN 1 Kota Gorontalo by employing Superitem essay test as a data collection tool. This descriptive analysis is described in the frequency distribution and histogram tables, whereas inferential analysis was performed by using ANCOVA test. The results showed that guided discovery learning model is preferable to compare to the conventional learning model in improving mathematics problem-solving ability.
Arthroscopic Management of Osteochondrosis of the Glenoid Cavity in a Dog
Authors: Bilmont Alexis , Mathon Didier , Autefage André
Published: July 2018

A 5 mo old English setter dog was presented with mild left forelimb lameness. Physical examination revealed pain upon shoulder palpation and extension. Mediolateral radiographs of both shoulders showed a subchondral bone defect in the mid-portion of the glenoid cavity. Computed tomography arthrography and arthroscopy revealed a cartilage flap, suggesting osteochondritis dissecans of the glenoid cavity. Subchondral bone cysts of the glenoid cavity and incomplete fusion of the supraglenoid tubercle were also observed. Arthroscopic removal of the fragment led to a favorable outcome.
Long-Term Outcome of Female Dogs Treated with Static Hydraulic Urethral Sphincter for Urethral Sphincter Mechanism Incompetence
Authors: Gomes Cesar , Doran Ivan , Friend Edward , Tivers Mickey , Chanoit Guillaume
Published: July 2018

The purpose of the study was to report the postoperative outcome, complications, and long-term follow-up of the use of a static hydraulic urethral sphincter for the management of urethral sphincter mechanism incompetence in female dogs. Medical records were reviewed to extract information on long-term (>365 days) outcome data. Telephone owner questionnaire was performed to assess postoperative urinary continence scores (scale 1–10, where 10 is complete continence) and the presence and frequency of complications. Twenty female dogs were included. Mean (±standard deviation) time to follow-up was 1,205.1 (±627.4) days. Median continence score/10 (range) was 3.5 (2–6) preoperatively, and 9.0 (7–10) at the last follow-up. Median continence score was significantly higher at all time points postoperatively compared with before surgery (P < .001). Complete continence was achieved in 90% of bitches. Minor complications occurred in 13 bitches and included dysuria (8), bacterial cystitis (8), longer urination time (10), incisional seroma (5), urinary retention (3), hematuria (2), and pain when urinating (2). Major complications occurred in one dog (static hydraulic urethral sphincter removed 28 mo after placement). Continence scores were sustainably improved in the long-term. Complications were mostly minor. Urinary tract infections were the most common but resolved with conventional antibiotic treatment.
Owner Perception of Outcome Following Permanent Tracheostomy in Dogs
Authors: Davis Anastacia Marie , Grimes Janet A. , Wallace Mandy L. , Vetter Catherine A.M. , Sterman Allyson , Mankin Kelley Thieman , Hlusko Katelyn C. , Matz Brad M. , Lin Samantha , Scharf Valery F. , Cornell Karen K. , Schmiedt Chad W.
Published: July 2018

The purpose of this study was to evaluate owner perception of outcome following permanent tracheostomy (PT) in dogs. Medical records of dogs who received PT from 2002 to 2016 were reviewed. A questionnaire was given to owners verbally or by e-mail to ascertain their perception of their dog’s outcome after PT. Median time to questionnaire administration from PT surgery was 608 days (64–3,708). Owner satisfaction after PT was high (89.7%), with the majority stating they would have the procedure performed again (79.5%). Owners reported an improvement in their dog's personality (30.8%) and increased activity (41%). Median survival time was 1,825 days (64–2,663), with 6 of 39 dogs (15.4%) alive at study end. Of the 33 dogs who died, 11 (33.3%) died from underlying respiratory conditions suspected to be related to the PT. The overall complication rate was 82.1%, with mucus secretion being the most common. Revision surgery was required in 30.8% of dogs (most commonly due to skin occlusion), and aspiration pneumonia occurred in 17.9% of dogs. Overall, owner satisfaction after PT in dogs is high despite intensive postoperative management, and long survival times can be achieved.
IDENTIFICAÇÃO DE DANOS EM VIGAS METÁLICAS UTILIZANDO MASSAS ITINERANTES ADICIONAIS, ANÁLISE EXPERIMENTAL.
Authors: LOPEZ PALECHOR ERWIN ULISES , BEZERRA LUCIANO MENDES , GIRÃO DE MORAIS MARCUS VINICIUS , RUBIM COSTA SILVA RAMON SALENO YURE
Published: July 2018

Devido à necessidade de monitoração contínua de estruturas, tais como: pontes, oleodutos, edifícios, barragens, entre outras, e também devido à necessidade de buscar técnicas eficientes e práticas que auxiliem nessa monitoração visando à identificação de danos, apresenta-se neste artigo um método para a identificação de danos em vigas metálicas, baseado na variação da frequência fundamental provocada pela aplicação de uma massa móvel adicional ao longo da estrutura. A aplicação do método e os resultados desta análise são apresentados para vigas metálicas de tamanho comercial e mostram que o método pode ser usado na detecção de danos ou de regiões com danos estruturais.
Letramento digital e literatura: saberes literários no mundo digital
Authors: De Assis Álida Laryssa Espozetti , Martins Neto Irando Alves , Macedo Rebeca Louzada
Published: July 2018

Partindo do pressuposto de que a escola, instituição fundamental para a formação do sujeito pensante, tem a responsabilidade de propiciar ao aluno condições para que ele possa se inserir, de maneira participativa, em diversas instâncias sociais, neste artigo, propomos um projeto em que alunos da terceira série do Ensino Médio produzam textos que alimentem um aplicativo sobre literatura para vestibulandos. Para tanto, sugerimos a realização de dez etapas, que descrevem o projeto desde a seleção de obras literárias a serem lidas até a avaliação do produto final. Com isso, esperamos que o projeto seja aplicado em diversos contextos escolares e, para além disso, que incite a criatividade de docentes para que o ampliem e elaborem novos projetos.
Perfil epidemiológico dos pacientes com leishmaniose tegumentar americana no município de Ilhéus – Bahia
Authors: Campos Soraya Sena , Campos Fleming Sena , Gois Glayciane Costa , Silva Tiago Santos
Published: July 2018

Objetivou-se analisar o perfil epidemiológico de 442 pacientes com leishmaniose tegumentar americana no município de Ilhéus entre os anos de 2007 a 2012. A coleta de dados foi realizada na vigilância epidemiológica do município Ilhéus, utilizando como banco de dados os casos notificados e digitados no sistema nacional de notificação de agravos de leishmaniose tegumentar americana. Foram analisadas informações sobre, sexo, faixa etária, escolaridade, critério de confirmação, tipo da leishmaniose, medicação utilizada, conclusão do caso. No município de Ilhéus a letalidade em leishmaniose tegumentar americana foi nula durante o período de estudo e a partir do ano de maior ocorrência houve um decréscimo dos casos positivos. Os indivíduos mais propícios à doença são do sexo masculino, entre 20 a 49 anos, residente em áreas rurais, pardos, autóctone. A forma mais incidente é a cutânea e a droga mais utilizada para o tratamento é a antimonial pentavalente. Não foi confirmada a sazonalidade da doença entre os meses e anos observados e nenhum surto da doença durante o período estudado no município de Ilhéus – Bahia. As informações deste estudo servirão para auxiliar o planejamento de ações epidemiológicas de saúde pública, visando medidas particulares de proteção conforme caracterização local. A partir destes resultados, espera-se mostrar a importância da notificação de investigação, diagnóstico precoce e tratamento eficaz para reduzir sequelas, bem como contribuir para a prevenção e controle da doença na cidade.
Comparação de duas técnicas parasitológicas na detecção de enteroparasitos em catadores no sul do Brasil
Authors: Carriconde Hernandes Juliana , Corrêa Érico Kunde , Corrêa Luciara Bilhalva , Dias Denise Gamio , Baccega Bruna , Nagel Andréia Saggin , Recuero Ana Lúcia Coelho , Brod Claudiomar Soares
Published: July 2018

Alguns pesquisadores e laboratórios clínicos utilizam apenas uma técnica para detecção de parasitos intestinais, podendo isto subestimar os achados. Enteroparasitos afetam principalmente populações com vulnerabilidade social, como os catadores. Alguns destes trabalhadores se reúnem em cooperativas, melhorando a condição de trabalho e o rendimento mensal, porém ainda não é o adequado, sendo por vezes insalubre. Nosso objetivo foi verificar a prevalência de enteroparasitos e comparar duas técnicas parasitológicas em suas medidas de efeito em catadores de material reciclável que trabalhavam em cooperativas no Sul do Brasil. Três amostras de fezes de 48 catadores, de seis cooperativas, foram coletadas em dias alternados, para a análise de parasitos. Duas técnicas de concentração de amostra foram utilizadas (Faust e Ritchie) e testadas para verificação da melhor a ser utilizada. A prevalência de parasitos em catadores foi de 62,5% (30/48) utilizando as duas técnicas em paralelo, sendo que quando utilizadas sozinhas, essa prevalência foi menor. Diagnosticaram-se helmintos e protozoários, tanto patogênicos quanto comensais. A partir da análise estatística, provou-se que as técnicas parasitológicas fornecem melhores resultados quando utilizadas em paralelo, ou seja, quando utilizamos as duas técnicas juntas e em três amostras de fezes.
"Disregard doctrine": a aplicação da desconsideração da personalidade jurídica
Authors: Costa Cazelatto Caio Eduardo , Segatto Antonio Carlos , Ide da Silva Naina Beatriz
Published: July 2018

A presente pesquisa teve como finalidade o estudo, a partir do método teórico, do instituto da desconsideração da personalidade jurídica, também denominada como disregard doctrine, em sua modalidade inversa. Em um primeiro momento, analisaram-se as teorias menor e maior da desconsideração da personalidade jurídica, com a seu aspecto de limitação patrimonial, que se mostra um instituto essencial para desenvolver e estimular a atividade econômica. Em sequência, abordou-se a desconsideração da personalidade jurídica inversa e suas classificações, como também as formas de organização societária que costumam ser empregadas fraudulentamente e que permitem a aplicação desse instituto. Também será tratado o uso do instituto pelo Poder Judiciário brasileiro, uma vez que, na ânsia por uma efetividade processual, o judiciário tem utilizado a teoria de forma excessiva, como uma regra geral e não como uma exceção, que seria a finalidade a que se destinava originalmente, banalizando e liquidando o conceito de personalidade jurídica. Por fim as questõesprocessuais e a aplicabilidade da desconsideração inversa da personalidade jurídica em relação às sociedades empresárias, à luz do Novo Código de Processo Civil.
Direito ao esquecimento: uma análise jurídica da jurisprudência atual do tribunal de justiça do distrito federal e dos territórios
Authors: Santos Júlio Edstron , Ribeiro Diaulas Costa , Sousa Maria Sariane de C.
Published: July 2018

Este artigo aborda o conflito entre o direito ao esquecimento e o direito à informação, especialmente em julgados do Tribunal de Justiça do Distrito Federal e dos Territórios, com o propósito de analisar como está sendo discutida esta matéria e quais fundamentos e ponderações utilizadas para a sua solução. Nesse caminho, a pesquisa foi realizada por meio de revisão bibliográfica sobre os direitos fundamentais, buscando-se ressaltar as ligações do princípio da dignidade da pessoa humana com o conceito do direito ao esquecimento. Ao final, realizou-se o resumo dos julgados, revelando os critérios de ponderação em cada caso concreto para solucionar o aludido conflito, buscando estabelecer até que ponto o grau de realização de um justifica o sacrifício do outro, tendo os dois a mesma relevância constitucional.
A influência do mercosul no desenvolvimento da economia criativa no Brasil
Authors: Lelis Henrique Rodrigues , Hubner de Lanna Costa Pablo Henrique , Volpini Silva Carla Ribeiro
Published: July 2018

A finalidade deste artigo é realizar uma análise sobre a importância do processo de integração regional do Mercosul para o desenvolvimento da Economia Criativa no Brasil. Para isto, o artigo apresenta o conceito de economia criativa, sua origem histórica e alguns fatos que evidenciam sua aplicabilidade, especialmente, o reconhecimento do tema como estratégico por diversos países e por organismos internacionais. Em seguida são estudados os impactos que a participação do Brasil junto ao bloco regional traz para o desenvolvimento do setor criativo brasileiro, especialmente no que concerne a falta de uma política econômica conduzida pelo Bloco regional. Conclui-se que, o atual estágio de desenvolvimento do Mercosul contribui para a economia criativa brasileira em alguns aspectos importantes, porém torna-se necessário um avanço e aprofundamento do sistema de integração para no mínimo, uma União Aduaneira completa, face às peculiaridades que o setor exige e a forte concorrência que ocorre com outros países cuja estratégia de ação no setor criativo já se encontra em estágios mais avançados. Em razão de seus objetivos, utilizou-se o método descritivo analítico como modalidade de raciocínio lógico e a pesquisa bibliográfica como técnica.
Direito aplicado ao agronegócio
Authors: Aiex Parra Rafaela
Published: July 2018

Resenha apresentada sobre a obra PARRA, Rafaela Aiex (Org.). Direito Aplicado ao Agronegócio: uma abordagem multidisciplinar. 1ª ed. Londrina: Thoth, 2018
Cuidar de idosos: um assunto de mulher?
Authors: Isaac Letícia , Ferreira Camila Rafael , Ximenes Vanessa Santiago
Published: July 2018

O gênero é considerado por muitos pesquisadores um fator que influencia a escolha do cuidador de idosos. Essa revisão narrativa visa refletir sobre a ação da cultura como agente determinante na escolha da mulher como responsável pelo cuidar. Este artigo preconiza a redefinição do critério de escolha dos cuidadores, de forma a estabelecer o papel de cuidar para o familiar mais apto a realizá-lo, não sendo o gênero o seu determinante. Espera-se reforçar a necessidade de desenvolvimento de políticas sociais direcionadas à mulher, considerando a sobrecarga que acomete o cuidador. Discute-se o valor social atribuído à atividade de cuidado e a importância de torná-la mais favorável a quem a exerce. Conclui-se que debater sobre a influência da cultura nessa atividade predominantemente feminina é uma tarefa ardilosa, porém necessária quando se visa melhorias para os envolvidos no contexto do cuidar.
Subsídio do sistema GTP (Geossistema- Território-Paisagem) na percepção de riscos ambientais: esboço metodológico
Authors: Das Neves Carlos Eduardo , Machado Gilnei , Camargo Karen Carla
Published: July 2018

Com o crescimento contínuo, desigual e contraditório das cidades, fala-se muito em ocupação de áreas de risco ambiental. Estes riscos são os mais diversos e vão desde um simples alagamento às enchentes e desmoronamentos, causando prejuízos econômicos e mortes. Tendo isso em consideração, se tem realizado a análise destas áreas, levando em consideração todo o arcabouço teórico e metodológico desenvolvido na academia, porém, pouco é considerado a opinião dos moradores destas áreas, os quais deveriam ser vistos como os maiores conhecedores do assunto. Esta pesquisa tem por objetivo apresentar uma matriz criada com esse objetivo, o de identificar a percepção das pessoas em relação aos riscos existentes nas áreas em que moram, diferenciando-a da perspectiva dos técnicos que avaliam essas áreas. Sua confecção, aplicação e debate estão embasados nas concepções teóricas do sistema tripolar Geossistema, Território e Paisagem. Para testar a matriz em questão, a mesma foi aplicada em vinte pontos ao longo da bacia do Ribeirão Quati, Londrina - Paraná. Tal exercício mostrou que a mesma permite uma análise mais complexa das variáveis de perigo e vulnerabilidade (componentes do risco), gerando ferramenta relevante ao planejamento e gestão ambiental urbana.
De betekenis van het Interbestuurlijk Programma voor het waterbeheer
Authors: Havekes H.J.M. (Herman)
Published: July 2018

De betekenis van het Interbestuurlijk Programma voor het waterbeheer

In deze bijdrage bespreekt de auteur het Interbestuurlijk Programma voor het waterbeheer, dat op 14 februari 2018 is gepresenteerd.
De Omgevingswet als aanjager voor een nieuwe coördinatieregeling in de Awb
Authors: Beurskens L.R.M.A. (Nard) , Ypinga J.H.N. (Jelmer) , de Graaf K.J. (Kars)
Published: July 2018

De Omgevingswet als aanjager voor een nieuwe coördinatieregeling in de Awb

Auteurs bespreken het voorstel voor een algemene coördinatieregeling in de Algemene wet bestuursrecht aan de hand van het wetsvoorstel dat op 17 januari 2018 door de regering ter consultatie is aangeboden.
Extraction of Phenylethanoid Glycosides from Cistanche tubulosa by High-Speed Shearing Homogenization Extraction
Authors: Pei Wenjing , Guo Ruili , Zhang Jinli , Li Xueqin
Published: July 2018

Background: Cistanche tubulosa is a well-known traditional Chinese medicine originating in Xinjiang. It is widely distributed in northern Africa, India, etc. Objective: The major bioactive component of C. tubulosa is phenylethanoid glycosides (PhGs). Echinacoside and acteoside are the indicative components for the determination of PhGs and are mainly used for liver protection, immune protection, etc. Therefore, it is very important to extract the PhGs from C. tubulosa. Methods: In this study, the ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and high-speed shearing homogenization extraction (HSHE) methods were compared. Furthermore, the extraction conditions of the HSHE method were optimized. Results: The results showed that the HSHE method was better than both the UAE and MAE methods, and the optimal extraction parameters of HSHE were an ethanol concentration of 50%, an extraction temperature of 70°C, a rotation speed of 16 000 rpm, an extraction time of 2 min, a solid-to-liquid ratio of 1:9, and one extraction cycle. The yields of echinacoside and acteoside were 1.366 and 0.519%, respectively, and the transfer rates of echinacoside and acteoside reached 87 and 94%, respectively. Conclusions: It can be concluded that the HSHE method is a simple, rapid, and efficient technique for extracting PhGs from C. tubulosa. Highlights: An efficient and ecofriendly HSHE method has been investigated for the extraction of PhGs from C. tubulosa. The optimum conditions of the HSHE method for the extraction of PhGs from C. tubulosa were obtained. This research provides a new method for the industrial extraction of PhGs from C. tubulosa.
Uncommon Types of Lung Carcinoma With Mixed Histology: Sarcomatoid Carcinoma, Adenosquamous Carcinoma, and Mucoepidermoid Carcinoma
Authors: Borczuk Alain C.
Published: July 2018

Context.—

Lung tumors are histologically heterogeneous, but classification of lung carcinoma has prognostic impact and increasingly, specific molecular correlates.

Objective.—

To update the gross, microscopic, and molecular pathology of unusual lung carcinomas to assure accurate classification. In entities with mixed histology, the recognition of specific features or rare patterns is critical to diagnosis. These diagnoses can identify tumors with aggressive clinical behavior, and diagnostic pitfalls can therefore result in underdiagnosis of these already rare entities. Incorrect classification of more indolent tumors into the more aggressive categories can also occur. In the area of molecular pathology, these unusual tumors have a specific spectrum of molecular alterations.

Data Sources.—

PubMed searches for lung and sarcomatoid carcinoma, pleomorphic carcinoma, blastoma, carcinosarcoma, and adenosquamous and mucoepidermoid carcinoma were undertaken and this information was integrated with clinical experience of the author.

Conclusions.—

These uncommon carcinomas have specific clinicopathologic features, and attention to their gross and microscopic pathology leads to classification with important associated molecular findings.
La production du droit autochtone : comportement, commandement, enseignement
Authors: Otis Ghislain
Published: July 2018

Ce texte présente quelques réflexions sur les modes de production, de détermination, de transformation et de transmission du droit autochtone en marge de l’État. Les systèmes juridiques autochtones ont souvent été refoulés et occultés par les politiques coloniales. Ils ont aussi subi des bouleversements en raison des transformations culturelles et économiques qui ont marqué la vie des sociétés autochtones. En conséquence, il peut être difficile aujourd’hui, surtout pour la société non autochtone, de saisir les processus par lesquels se forment et se transforment les systèmes juridiques autochtones. L’auteur montre d’abord que les cultures juridiques autochtones restent encore aujourd’hui fortement ancrées dans le droit spontané, c’est-à-dire un droit inhérent à la compétence originelle du groupe et donc créé sans l’intervention de l’autorité politique, du juge ou du juriste savant. Il souligne toutefois aussi que l’univers juridique autochtone se trouve de plus en plus confronté à la question de l’autorité et du commandement comme foyers de normes, ce qui pose la question des rapports de pouvoir et de la place du droit écrit ainsi que de sa relation, de tension ou de coopération, avec le droit non écrit. Enfin, l’auteur montre comment la quête de connaissance des traditions juridiques autochtones, la volonté de les revitaliser dans la régulation quotidienne des communautés et le besoin de les rendre plus lisibles pour les non-autochtones, ont induit l’émergence d’une école doctrinale autochtoniste mobilisant les récits et la tradition orale autochtones pour en tirer des enseignements susceptibles d’inspirer des initiatives d’autodétermination plus effectives et légitimes.
Porcupine and Other Stories: Legal Relations in Secwépemcúlecw
Authors: Friedland Hadley , Leonard Bonnie , Asch Jessica , Mortimer Kelly
Published: July 2018

For thousands of years, Secwépemc laws (like other Indigenous laws) related to the Secwépemc lands, or “Secwépemcúlecw,” developed and were learned and practiced within a context where the personhood of Secwépemc individuals, as well as animals and the earth itself, was not in dispute. Nor was the existence, legitimacy or efficacy of Secwépemc laws. All of these crucial legal relationships still exist, and are ongoing. However, for the past 150 years or so, Secwépemc laws, and people, have lived in relation to something quite distinct — a set of laws that were jurispathic in nature —laws that would not recognize or tolerate any other law but themselves. The Secwépemc Nation’s resilience and perseverance in upholding and revitalizing Secwépemc laws in the face of this colonial disregard, attests to their strength and enduring value. In this article, the authors discuss the purpose, as well as some of the methods, outcomes and limits of the Secwépemc Lands and Resources Laws project produced in collaboration with the University of Victoria Indigenous Law Research Unit. They then examine present interactions between Secwépemc and state land and resources laws operating within Secwépemcúlecw, including the challenges and limited opportunities that exist within the way these legal and political relations are currently structured and implemented on the ground. Finally, they draw on the Secwépemc “Story of Porcupine” to suggest a constructive way forward towards a more mutually respectful Nation-to-Nation relationship between the Secwépemc people and the Canadian State.
Rapid ecological specialization despite constant population sizes
Authors: Rakotoarivelo Andrinajoro R , O'Donoghue Paul , Bruford Michael W , Moodley Yoshan
Published: July 2018

Background. The bushbuck, Tragelaphus scriptus, is the most widespread and ecologically diverse ungulate species complex within the spiral-horned antelopes. This species was recently found to consist of two genetically divergent but monophyletic Scriptus and Sylvaticus lineages, which are paraphyletic at mitochondrial (mt)DNA owing to an ancient interspecific hybridization event. The Scriptus lineage inhabits the north-western half of the African continent while Sylvaticus is found in the south-eastern half. Here we test hypotheses of historical demography and adaptation in bushbuck using a higher-resolution framework, with four nuclear (MGF, PRKCI, SPTBN, and THY) and three new mitochondrial markers (cytochrome b, 12S rRNA, and 16S rRNA). Methods. Genealogies were reconstructed for the mitochondrial and nuclear data sets, with the latter dated using fossil calibration points. We also inferred the demographic history of Scriptus and Sylvaticus using coalescent-based methods. To obtain an overview of the origins and ancestral colonisation routes of ancestral bushbuck sequences across geographic space, we conducted a discrete Bayesian phylogeographic analysis on our nuclear DNA data set. Results. Both nDNA and mtDNA support previously findings of two genetically divergent Sylvaticus and Scriptus lineages, with no allele sharing despite coming into secondary contact at several geographic locations. The three mtDNA loci confirmed 15 of the previously defined ecotypes, including those with convergent phenotypes. However, the nuclear tree showed less phylogenetic resolution at the more derived parts of the genealogy, possibly due to incomplete lineage sorting of the slower evolving nuclear genome. The only exception to this was the montane ecotype meneliki (Sylvaticus) of the Ethiopian highlands, which formed a monophyletic group at three of four nDNA loci. We dated the coalescence of the two lineages to a common ancestor ∼2.54 million years ago. Both marker sets revealed similar demographic histories of constant population size over time. We show that the bushbuck likely originated in North-East Africa, with Scriptus colonising suitable habitats towards west of the rift and Sylvaticus diffusing from east of the rift into southern Africa. Discussion. Despite lower levels of genetic structure at nuclear loci, we confirmed the independent evolution of the Menelik’s bushbuck relative to the phenotypically similar montane ecotypes in East Africa, adding further weight to previous suggestions of convergent evolution within the bushbuck complex. Perhaps the most surprising result of our analysis was that both Scriptus and Sylvaticus populations remained relatively constant throughout the Pleistocene, which is remarkable given that this was a period of major climatic and tectonic change in Africa, and responsible for driving the evolution of much of the continents extant large mammal diversity.
Data security issues in the realm of mobile cloud computing: A survey
Authors: Anwar Mohammed-Ali
Published: July 2018

Mobile Cloud Computing (MCC) is a recent technological development, which has emerged from two popular technology trends; mobile computing and cloud. In essence it revolutionises the capabilities of mobile devices by integrating both storage and processing of the cloud environment with mobile computing and in doing so providing greater optimisation and operating power, allowing for transparent and seamless use of resources provided by the cloud. However, expanding the capability of resource constrained mobile devices in this manner comes at a price. There are many risks associated with the security of data within the cloud environment and as MCC essentially uses the cloud, it also inherits any security issues that are associated with cloud computing. The aim of this survey is to identify potential data security issues, and analyse and present some pioneering security mechanisms and finally suggest some future directions for better data security with MCC.
Neurexin directs partner-specific synaptic connectivity in C. elegans
Authors: Philbrook Alison , Ramachandran Shankar , Lambert Christopher M , Oliver Devyn , Florman Jeremy , Alkema Mark J , Lemons Michele , Francis Michael M
Published: July 2018

In neural circuits, individual neurons often make projections onto multiple postsynaptic partners. Here, we investigate molecular mechanisms by which these divergent connections are generated, using dyadic synapses in C. elegans as a model. We report that C. elegans nrx-1/neurexin directs divergent connectivity through differential actions at synapses with partnering neurons and muscles. We show that cholinergic outputs onto neurons are, unexpectedly, located at previously undefined spine-like protrusions from GABAergic dendrites. Both these spine-like features and cholinergic receptor clustering are strikingly disrupted in the absence of nrx-1. Excitatory transmission onto GABAergic neurons, but not neuromuscular transmission, is also disrupted. Our data indicate that NRX-1 located at presynaptic sites specifically directs postsynaptic development in GABAergic neurons. Our findings provide evidence that individual neurons can direct differential patterns of connectivity with their post-synaptic partners through partner-specific utilization of synaptic organizers, offering a novel view into molecular control of divergent connectivity.