bluuebunny/crossref_metadata_2025 huggingface dataset:
The Politics of African Literature
Authors: Attwell David
Published: April 2019

Noting that many pre- and post-colonial oral forms have always been political, the article focuses on the literary culture wars that arose in the context of mid-20th-century decolonization. These debates include the question of whether writers should use indigenous or colonial languages; the complexities of publishing with access to local and international markets; the adaptation and indigenization of European forms to African value-systems, mythic structures and social realities; and the relationship between cultural decolonization and debates in Europe after 1968, when the emphasis fell on questioning realism. The article concludes by noting that the cultural nationalism of the 20th century is giving way to new forms of transnational politics.
Development Trajectories in Africa
Authors: Mshomba Richard E.
Published: April 2019

Since independence, African states have been striving for economic development, but relatively few countries have achieved their goal. Between 1970 and 2016, real GDP per capita in sub-Saharan Africa grew by an annual average of just 0.48%. However, there was a wide range of economic performance across different countries, as well as clear variation in growth rates over time. Countries such as the Central African Republic, Democratic Republic of Congo, Liberia, and Madagascar had, on average, a negative growth rate in terms of real GDP per capita. Meanwhile, countries such as Botswana, Lesotho, Mauritius, Seychelles, and Swaziland had positive average annual growth rates of at least 3%. The differences in economic growth rates reflect the diversity of economic structures, governance, and political stability across African states. Although deeper economic integration among African countries may work to reduce the large disparities in economic development, any projections must nonetheless recognize that countries will differ in their economic trajectories.

Variation over time is also important. The dominant patterns of economic development in sub-Saharan Africa in the 1980s and 1990s on the one hand, and the 1970s and past the 1990s on the other, were quite different, reflecting a long business cycle. If we look solely at economic growth statistics, the 1980s and 1990s can be described as lost decades. On average, real GDP per capita on the continent declined annually by 1.54% and 0.62% in the 1980s and 1990s, respectively. By contrast, between 2000 and 2016, real GDP per capita increased by an annual average of 2.13%.

One important debate has focused on whether these shifts are primarily the result of domestic or international factors. Structural adjustment programs (SAPs) imposed by the International Monetary Fund (IMF) and the World Bank have been blamed for the decline in the economic fortunes of African countries in the 1980s. At the same time, they are praised for pulling many countries out of unsustainable macroeconomic policies. Moreover, a balanced overview of Africa’s development trajectory must conclude that even without major policy shifts such as those brought forth by the SAPs, many countries would still have remained highly dependent on one or just a few commodities, and would therefore have continued to experience wild swings in their business cycles in the absence of international intervention.

The lack of economic diversification of many economies on the continent means that the future is hard to predict. However, the prerequisites for a prosperous Africa are not a mystery—they include good governance, economic diversity, and genuine economic integration.
The Extended Scope of Accountability in Public Administration
Authors: Mulgan Richard
Published: April 2019

The accountability of governments to their citizens is usually framed within a relationship of principal and agent in which the government, as agent, is obliged to answer to the citizens as agents. It is also commonly located within a structure of representative democracy where political leaders are elected by, and answerable to, the voters. However, these two theoretical frames do not adequately capture the relations of government to their citizens or the parameters of government accountability.

Governments increasingly operate through non-hierarchical networks that are not subject to the vertical accountability assumed in principal-agent theory. Instead, networks offer alternative, informal accountability mechanisms based on horizontal relationships. These are evident, for example, in the responsiveness of professionals to their clients and the mutual accountability of network members to one another. These mechanisms have a sufficient share in the characteristics normally associated with accountability, including the obligations to inform, discuss, and accept consequences, for them to count as mechanisms of accountability in the usual sense. Redefinition of accountability, for instance to exclude the requirement of answering to another person or body, while understandable, is not essential.

Accountability mechanisms also function without the support of effective democratic elections. For instance, formal institutions of horizontal accountability, such as courts and anti-corruption agencies, can operate in non-democratic regimes and are better seen as conditions of representative democracy rather than as consequences. Partially democratic or authoritarian regimes also exhibit various forms of social accountability in which civil society organizations call governments directly to account without recourse to state-based agencies of accountability. Large authoritarian regimes can encourage limited accountability processes as a means of bringing public pressure to bear on recalcitrant cadres. To be effective, however, all such measures require at least some legally robust support from government institutions.
Courts in Latin American Politics
Authors: Gonzalez-Ocantos Ezequiel
Published: April 2019

In the aftermath of the third wave of democratization, Latin American courts left behind decades of subservience, conservatism, and irrelevance to become central political players. They now serve as arbiters in struggles between the elected branches, and increasingly affirm fundamental rights. Indeed, some rulings champion highly controversial rights and have huge budgetary implications, sending shock waves across these new democracies. What explains this unprecedented expansion of judicial power? In trying to answer this fundamental question about the functioning of contemporary democracies, scholars of Latin America have developed a truly vibrant and theoretically dynamic body of work, one that makes essential contributions to our knowledge of judicial politics more generally. Some scholars emphasize the importance of formal judicial reforms initiated by politicians, which resulted in more autonomous and politically insulated courts. In so doing, they address a central puzzle in political science: under what conditions are politicians willing to accept limits to their power? Inspired by rational choice theory, other authors zoom in on the dynamics of inter-branch interactions, to arrive at a series of propositions about the type of political environment in which courts are more capable to assert their power. Whereas this approach focuses on the ability of judges to exercise power, a third line of scholarship looks at how ideas about the law and judicial role conceptions affect judges’ willingness to intervene in high-stakes political struggles, championing some values and interests at the expense of others. Finally, more recent work asks whether assertions of judicial power make a difference in terms of rights effectiveness. Understanding the consequences of judicial decisions is essential to establishing the extent to which more assertive courts are actually capable of transforming the world around them.
Voter Information Processing and Political Decision Making
Authors: Nai Alessandro
Published: April 2019

Contemporary political information processing and the subsequent decision making mechanisms are suboptimal. Average voters usually have but vague notions of politics and cannot be said to be motivated to invest considerable amount of times to make up their minds about political affairs; furthermore, political information is not only complex and virtually infinite but also often explicitly designed to deceive and persuade by triggering unconscious mechanisms in those exposed to it. In this context, how can voters sample, process, and transform the political information they receive into reliable political choices? Two broad set of dynamics are at play. On the one hand, individual differences determine how information is accessed and processed: different personality traits set incentives (and hurdles) for information processing, the availability of information heuristics and the motivation to treat complex information determine the preference between easy and good decisions, and partisan preferences establish boundaries for information processing and selective exposure. On the other hand, and beyond these individual differences, the content of political information available to citizens drives decision making: the alleged “declining quality” of news information poses threats for comprehensive and systematic reasoning; excessive negativity in electoral campaigns drives cynicism (but also attention); and the use of emotional appeals increases information processing (anxiety), decreases interest and attention (rage), and strengthens the reliance on individual predispositions (enthusiasm).

At the other end of the decisional process, the quality of the choices made (Was the decision supported by “ambivalent” opinions? And to what extent was the decision “correct”?) is equally hard to assess, and fundamental normative questions come into play.
Using Action Research to Improve Race Relations in Prisons
Authors: Ellis Tom
Published: April 2019

Tackling racism in prisons has a relatively long policy, practice, and research history in England and Wales. However, clear evidence of success in reducing racism in prisons has been, and still is, difficult to find. This article is based on a unique study that was carried out either side of the new millennium (late 1999 to mid-2001), but no equivalent exercise has been repeated since. Due to a unique set of circumstances at the time the study was carried out, it became possible to employ an action research approach that required policymakers, practitioners, volunteers, and researchers to agree on: an emergent research design; implementation; intervention; and measurement. There are many forms of action research, but this study could best be defined as a “utilization-focused evaluation, which is particularly applicable to the criminal justice environment. This approach also included elements of participatory action research.” The emphasis here is to show how the action research approach can be both more systematic and more flexible than traditional social science approaches. This applies to both epistemological and research methods considerations, because, by combining theory and action, action research can provide a more viable way of ensuring that policy works in practice, and is sensitive to unique institutional exigencies. Throughout, discussion is contextualised using policy, research and methodology texts from the period when the research was commissioned, but given an overall methodological context by referencing more recent methodology text books.

The article first outlines the context in which the action research study was commissioned, before providing a summary of the international research findings on race relations in prisons, from which key concepts for the project were initially operationalized. The chapter then explains how the specific participatory action research approach was selected as the most appropriate design, the extent to which the approach was successful, and why. The article ends with a discussion of the implications of findings and conclusions from this study for current policy and methodological approaches.
Gangs and Violence
Authors: Bullard Haley , Reid Shannon
Published: April 2019

Much of the ongoing concern about the presence of gangs and gang members in the community has to do with the association between street gangs and violence. Decades of research on street gangs demonstrates the complexity of the violent perpetration and victimization of gang members. Although the violence attributed to gang members reached its peak in the late 1980s and early 1990s, gang members continue to be disproportionately involved in violence, both as perpetrators and victims. Understanding gang violence requires careful consideration of the overlapping and intersecting relationships between violence and gang identity, victimization, perpetration, gender, and space. Violence plays an important role in the creation and maintenance of gang identity. Research on violence participation by gang members has demonstrated that gang violence can have both symbolic and instrumental purposes, and that this violence helps the gang build a collective identity and makes violence more normative. Despite some continued misconceptions about the role of female gang members and their presence in gangs, women make up a substantial portion of gang members, and any discussion of the relationship between gangs and violence must also consider the impact of gender on violence participation and victimization. Both male and female gang members are impacted by violence, but levels of participation and types of risk can vary by gender. The complex and gendered aspects of gang violence can make the prevention, intervention, and suppression of gang violence difficult tasks for law enforcement and policymakers. There are a range of perspectives on how best to reduce gang violence. Some researchers advocate early prevention programs to keep youth from joining gangs; others focus on ways to pull youth out of gangs at critical moments, such as when they enter emergency services. Other programs and policies are aimed at reducing gang violence that is ongoing in the community. These programs, such as Operation Ceasefire and Project Safe Neighborhoods, have utilized a focused deterrence framework to curb gang violence. All of these programs are aimed at reducing the amount of violence gang members participate in an attempt to minimize the risk of future violent victimization. Research on gang violence continues to grow and includes new avenues of research. The utilization of innovative methodologies, such as social network analysis, and new areas of research, such as examining the impact of social media on gang violence, continue to advance our knowledge of gang violence and its causes, correlates, and impact.
Police Training and Education
Authors: DeCarlo John
Published: April 2019

The issue of educational entry requirements for police officers has been a perennial one. Since August Vollmer first broached the topic of police education as a serious consideration, there have been opinions on both sides of the subject. A number of presidential commissions have examined the question of a police minimum education requirement, and numerous academic studies have attempted to empirically define predictor variables which correlate higher education and different training methods with police performance. Although progress has been made in training and educating police differently, policy on police training continues to remain an important subject.
Errors of Justice in Policing
Authors: Forst Brian
Published: April 2019

Errors of justice are a serious problem, and the police contribute substantially to them. Much can be done to reduce these errors, involving overreaction, underreaction, and misreaction that imposes either due process errors on the arrested or errors of impunity on the community, or both. The sources, severity, and frequency of these errors vary considerably, and they vary by circumstance and the characteristics of the victim, suspect, and community. Dealing with them effectively begins with understanding these variants and the costs, both social and fiscal, of each type of error on the community. Police legitimacy is likely to be enhanced in the process, especially in an era of mistrust of public institutions.
Autonomic Control of Immune Function
Authors: Wohleb Eric S.
Published: April 2019

Proper immune function is critical to maintain homeostasis, recognize and eliminate pathogens, and promote tissue repair. Primary and secondary immune organs receive input from the autonomic nervous system and immune cells express receptors for epinephrine, norepinephrine, and/or acetylcholine. Through direct signaling the autonomic nervous system controls immune function by altering immune cell development, initiating redistribution of immune cells throughout the body, and promoting molecular pathways that shift immune cell reactivity. This neuroimmune communication allows the autonomic nervous system to shape immune function based on physiological and psychological demands.
Simple and Complex Views of Teacher Development
Authors: Jones Jane , Ellis Viv
Published: April 2019

Development is a keyword in the vocabulary of teacher education research. Keywords are high-frequency words and phrases that while bringing people together in conversation are nonetheless sites of significant contestation in the field. At its most basic level, in the phrase “teacher development,” development can refer either to the development of the teacher (personal-professional formation) or to the development of the practice (teaching). Adopting descriptive categories from literacy research to delineate “simple” and “complex” views on the underlying questions of development, it becomes clear that, within such a dichotomous construction, “simple” approaches are insufficient either to describe or to plan for becoming a teacher and experiencing growth in professional practice. Underpinning these “simple” and “complex” views in the research on teacher education, divergent perspectives on formation (e.g., the “natural born teacher” vs. becoming through struggling with an identity) and learning (e.g., high-intensity training in “moves” vs. complex trajectories of participation in social practices and the growth of critical reflexivity). Thus, in the research literature, it is possible to discern critical-humanistic and also techno-rationalist clusters of meaning: optimistic yet expansive understandings of learning and change alongside well-intentioned oversimplifications of inherently contingent and uncertain situations. Navigating these clusters is consequential for how the work of teaching and of educating teachers can be understood. Indeed, the vocabulary of teacher education research needs to be examined much more closely so that, by interrogating keywords such as development, new spaces for a more critical deliberation of becoming a teacher and for more transformative practices of both teaching and teacher education can be stimulated.
The Progressive Writers Association
Authors: Ramnath Maia
Published: April 2019

The Progressive Writers Association (PWA) was founded in the mid-1930s by a group of South Asian leftist intellectuals who moved between metropolitan and colonial contexts. Announcing itself with a manifesto written in London in 1934 and reaching its peak of influence as a movement and an organization inside India in the 1940s, the PWA was a significant component of the South Asian cultural left. Its interlinked political and literary aims (founded upon the principle that the political and the literary must be interlinked) addressed anticolonialism and radical social change at home, while simultaneously positioning itself as part of the international popular front against fascism. As the Progressive writers moved into the post-independence decolonizing period, they identified closely with communist movements in India and Pakistan, while simultaneously positioning themselves at the forefront of Afro-Asian or Third World liberation solidarity formations during the Cold War. Thus these writers occupied a dual position, as simultaneously the cultural wing of the South Asian left and the South Asian manifestation of an international anti-imperialist movement that in both periods viewed art, literature, and ideology as crucial components of building socialism and decolonization.
Biological and Social Aspects of Human Infertility: A Global Perspective
Authors: Thoma Marie , Fledderjohann Jasmine , Cox Carie , Kantum Adageba Rudolph
Published: April 2019

Infertility remains a neglected area in sexual and reproductive health, yet its consequences are staggering. Infertility is estimated to impact about 10–25% (estimates range from 48 to 180 million) of couples of reproductive age worldwide. It is associated with adverse physical and mental health outcomes, financial distress, severe social stigma, increased risk of domestic abuse, and marital instability. Although men and women are equally likely to be infertile, women often bear the societal burden of infertility, particularly in societies where a woman’s identity and social value are closely tied to her ability to bear children. Despite these consequences, disparities in access to infertility treatment between low- and high-income populations persist given the high cost and limited geographic availability of diagnostic services and assisted reproductive technologies. In addition, a considerable proportion of infertility is a result of preventable factors, such as smoking, sexually transmitted infections, pregnancy-related infection or unsafe abortion, and environmental contaminants.

Accordingly, programs that address the equitable prevention and treatment of infertility are not only in keeping with a reproductive rights perspective but can also improve public health. However, progress on infertility as a global concern in the field of sexual and reproductive health and rights is stymied by challenges in understanding the global epidemiology of infertility, including its causes and determinants, barriers to accessing quality fertility care, and a lack of political will and attention to this issue. The tracking and measurement of infertility are highly complex, resulting in considerable ambiguity about its prevalence and stratification in reproduction globally. A renewed global focus on infertility epidemiology, risk factors, and access to and receipt of quality of care will support individuals in trying to reach their desired number and spacing of children and improve overall health and well-being.
International/Global Political Sociology
Authors: Nabers Dirk , Stengel Frank A.
Published: April 2019

International Political Sociology (IPS) emerged as a subfield of International Relations (IR) in the early 2000s. IPS itself may be understood as constituted by a field of tension between the concepts of “the International,” “the Political,” and “the Social.” Against this background, the centrality of anarchy and sovereignty as the fundamental structuring principles of international politics are increasingly called into question. While IPS remains an exciting, creative and important endeavor, researchers are also exploring paths toward what might be called a Global Political Sociology (GPS). Although IPS has become more global in orientation, more sociological with respect to sources, and more political in its stance, three ongoing shifts need to be made in order to transform IPS into GPS: first, insights from disciplines foreign to IR—both Western and non-Western—need to be employed in order to illustrate that specific localities have implications for the global as a whole; second, the continued engagement with causal theorizing must be replaced with contingency and undecidability as the fundamental constituting features of the political; and third, if the international that has been the nucleus of IR activities for decades, but impedes our understanding of politics instead of stimulating it, then alternative ways of theorizing global politics must be explored.
Postconflict Reparations
Authors: Dixon Peter J. , Moffett Luke , Rudling Adriana
Published: April 2019

The devastation brought by war leaves behind irreparable loss and destruction. Yet over the past 100 years there has been a concerted effort by states, both within their territory and following conflicts with other states, to resolve the past through reparations. As a legal and political tool, reparations can affirm values in a postconflict society through recognising suffering and responsibility, as well as helping those most affected by the conflict to cope with their loss. However, the scale of harm and damage of war may devastate a state’s capacity to redress all victims, and states may have more pressing priorities to reconstruct and encourage development. While the guns have been silenced, the motivations and ideologies that fueled and justified violence may continue, politicising debates over which victims are deserving of reparation or absolving the responsibility of certain actors, causing reparations to be delayed or dropped. Where reparations are made, furthermore, assessments of their effectiveness in meeting their goals are both challenging and necessary. This article addresses these issues, providing a snapshot of the key debates in the area, the continuing gaps, and the need for further research.
Peace: A Conceptual Survey
Authors: Diehl Paul F.
Published: April 2019

Peace is an elusive concept with many different meanings. Traditionally, it has been equated with the absence of war or violence, but such “negative peace” has limited value as it lumps wildly disparate situations together, such as rivalries (India–Pakistan) and close political relationships (e.g., European Union). Nevertheless, this conception remains the predominant approach in theory, research, teaching, and policy discourse. “Positive peace” definitions are much broader and encompass aspects that go beyond war and violence, but there is far less consensus on those elements. Conceptions encompass, among other elements, human rights, justice, judicial independence, and communication components. In the early 21st century, a number of alternative conceptions and frameworks have been developed to modify, extend, or replace the core concepts of negative and positive peace. Research on positive peace and alternatives is also comparatively underdeveloped. Peace can also be represented as binary (present or not) or as a continuum (the degree to which peace is present). Peace can be applied at different levels of analysis. At the system level, it refers to the aggregate or global conditions in the world at a given time. At the dyadic or k‑adic level, it refers to the state of peace in relationships between two or more states. Finally, internal peace deals with conditions inside individual states, and the relationships between governments, groups, and individuals. Aspects of peace vary according to the level of analysis, and peace at one level might not be mirrored at other levels.
The Movement for Japanese American Redress
Authors: Asaka Megan
Published: April 2019

The Japanese American Redress Movement refers to the various efforts of Japanese Americans from the 1940s to the 1980s to obtain restitution for their removal and confinement during World War II. This included judicial and legislative campaigns at local, state, and federal levels for recognition of government wrongdoing and compensation for losses, both material and immaterial. The push for redress originated in the late 1940s as the Cold War opened up opportunities for Japanese Americans to demand concessions from the government. During the 1960s and 1970s, Japanese Americans began to connect the struggle for redress with anti-racist and anti-imperialist movements of the time. Despite their growing political divisions, Japanese Americans came together to launch several successful campaigns that laid the groundwork for redress. During the early 1980s, the government increased its involvement in redress by forming a congressional commission to conduct an official review of the World War II incarceration. The commission’s recommendations of monetary payments and an official apology paved the way for the passage of the Civil Liberties Act of 1988 and other redress actions. Beyond its legislative and judicial victories, the redress movement also created a space for collective healing and generated new forms of activism that continue into the present.
Central America-US Relations
Authors: McCormick Evan D.
Published: April 2019

Since gaining independence in 1823, the states comprising Central America have had a front seat to the rise of the United States as a global superpower. Indeed, more so than anywhere else, the United States has sought to use its power to shape Central America into a system that heeds US interests and abides by principles of liberal democratic capitalism. Relations have been characterized by US power wielded freely by officials and non-state actors alike to override the aspirations of Central American actors in favor of US political and economic objectives: from the days of US filibusterers invading Nicaragua in search of territory; to the occupations of the Dollar Diplomacy era, designed to maintain financial and economic stability; to the covert interventions of the Cold War era. For their part, the Central American states have, at various times, sought to challenge the brunt of US hegemony, most effectively when coordinating their foreign policies to balance against US power. These efforts—even when not rejected by the United States—have generally been short-lived, hampered by economic dependency and political rivalries. The result is a history of US-Central American relations that wavers between confrontation and cooperation, but is remarkable for the consistency of its main element: US dominance.
Foreign Travelers’ Accounts and Fanny Calderón de la Barca’s Life in Mexico
Authors: Parra Lazcano Lourdes
Published: April 2019

Foreign travelers arrived in large numbers in Mexico, especially after Mexican War of Independence, to see the country and access its commercial potential. Each of them talked about the Valley of Mexico, its richness and human diversity. The way these travelers wrote about their “gazes” over this valley—in particular Fanny Calderón de la Barca—is key to understanding the politics of their trips. After their initial viewing, foreign travelers described the Mexican social and political situation as ripe for exploitation and improvement. Despite the fact that these travel accounts consider only an arbitrary section of the Mexican reality, affected by the bias and life history of each writer, they offer valuable material in their portrayal of Mexican society at that time. Hernán Cortés and Alexander von Humboldt’s views of the Mexican Valley were highly influential for the subsequent foreign travelers who went to Mexico during the 19th century, mainly from the United Kingdom, central Europe, and the United States. The work of Fanny Calderón de la Barca, and her gaze as it falls upon the Valley of Mexico, reflect the politics of mid-19th-century Mexico.
philosophy, modern reception of
Authors: Glidden David K.
Published: April 2019

Ancient philosophy’s modern reception reflects methods of transmission and dissemination of ancient philosophic texts. Ancient Greco-Roman philosophy impacted modernity via six means of influence: printed books, libraries, critical scholarship, vernacular translations, eclectic borrowing, and thematic resonance.
philosophy, early modern reception of
Authors: Corrias Anna
Published: April 2019

The early modern period saw a tremendous revival in interest in ancient philosophy. New Platonic texts became available. New ways of analyzing Aristotle were explored. Stoic and Epicurean philosophy began to exert an influence on key thinkers. The impact of ancient philosophy was felt in a number of key areas, these included natural history, theology, and epistemology.
lex Agraria, 111 BCE
Authors: Beggio Tommaso
Published: April 2019

The lex Agraria dating from 111 bce is an epigraphic law dealing with the distribution and privatisation of public land (ager publicus) in Italy and the provinces. In its first part, concerning public land in Italy, the law first describes five different categories of land declared to be private, before identifying other kinds of land that were and should remain public. In the second part, relating to land in Africa and Greece, the law establishes rules mainly regarding pasture land and the public sale of land, which then had to be declared private; nonetheless, this land was subject to the payment of the vectigal. Therefore, the lex Agraria can be considered as a law that consolidated some of the achievements of the Gracchan reforms that took a significant step towards the privatisation of ager publicus. However, the question remains open as to whether the lex Agraria could be associated with one of the three post-Gracchan laws cited by Appian (B Civ. 1.27) and, if so, which one. A long-standing scholarly debate has arisen from these questions, and various theories have been advanced over the decades.
Englishes in England, Scotland, Wales, and Ireland
Authors: Hickey Raymond
Published: April 2019

The differentiation of English into separate varieties in the regions of Britain and Ireland has a long history. This is connected with the separate but related identities of England, Wales, Scotland, and Ireland. In this chapter the main linguistic traits of the regions are described and discussed within the framework of language variation and change, an approach to linguistic differentiation that attempts to identify patterns of speaker social behavior and trajectories along which varieties develop.

The section on England is subdivided into rural and urban forms of English, the former associated with the broad regions of the North, the Midlands, East Anglia, the Southeast and South, and the West Country. For urban varieties English in the cities of London, Norwich, Milton Keynes, Bristol, Liverpool, and Newcastle upon Tyne is discussed in the light of the available data and existing scholarship. English in the Celtic regions of Britain and Ireland is examined in dedicated sections on Scotland, Wales, and Ireland. Finally, varieties of English found on the smaller islands around Britain form the focus, i.e., English on the Orkney and Shetland islands, the Isle of Man, and the Channel Islands.
A History of Creole Studies
Authors: Moreira de Sousa Silvio , Mücke Johannes , Krämer Philipp
Published: April 2019

As an institutionalized subfield of academic research, Creole studies (or Creolistics) emerged in the second half of the 20th century on the basis of pioneering works in the last decades of the 19th century and first half of the 20th century. Yet its research traditions—just like the Creole languages themselves—are much older and are deeply intertwined with the history of European colonialism, slavery, and Christian missionary activities all around the globe. Throughout the history of research, creolists focused on the emergence of Creole languages and their grammatical structures—often in comparison to European colonial languages. In connection with the observations in grammar and history, creolists discussed theoretical matters such as the role of language acquisition in creolization, the status of Creoles among the other languages in the world, and the social conditions in which they are or were spoken. These discussions molded the way in which the acquired knowledge was transmitted to the following generations of creolists.
Personal/Participant/Inhabitant in Morphology
Authors: Andreou Marios
Published: April 2019

The category of Personal/Participant/Inhabitant derived nouns comprises a conglomeration of derived nouns that denote among others agents, instruments, patients/themes, inhabitants, and followers of a person. Based on the thematic relations between the derived noun and its base lexeme, Personal/Participant/Inhabitant nouns can be classified into two subclasses. The first subclass comprises derived nouns that are deverbal and carry thematic readings (e.g., driver). The second subclass consists of derived nouns with athematic readings (e.g., Marxist).

The examination of the category of Personal/Participant/Inhabitant nouns allows one to delve deeply into the study of multiplicity of meaning in word formation and the factors that bear on the readings of derived words. These factors range from the historical mechanisms that lead to multiplicity of meaning and the lexical-semantic properties of the bases that derived nouns are based on, to the syntactic context into which derived nouns occur, and the pragmatic-encyclopedic facets of both the base and the derived lexeme.
The Status of Heads in Morphology
Authors: Moskal Beata , Smith Peter W.
Published: April 2019

Headedness is a pervasive phenomenon throughout different components of the grammar, which fundamentally encodes an asymmetry between two or more items, such that one is in some sense more important than the other(s). In phonology for instance, the nucleus is the head of the syllable, and not the onset or the coda, whereas in syntax, the verb is the head of a verb phrase, rather than any complements or specifiers that it combines with. It makes sense, then, to question whether the notion of headedness applies to the morphology as well; specifically, do words—complex or simplex—have heads that determine the properties of the word as a whole? Intuitively it makes sense that words have heads: a noun that is derived from an adjective like redness can function only as a noun, and the presence of red in the structure does not confer on the whole form the ability to function as an adjective as well.

However, this question is a complex one for a variety of reasons. While it seems clear for some phenomena such as category determination that words have heads, there is a lot of evidence to suggest that the properties of complex words are not all derived from one morpheme, but rather that the features are gathered from potentially numerous morphemes within the same word. Furthermore, properties that characterize heads compared to dependents, particularly based on syntactic behavior, do not unambigously pick out a single element, but the tests applied to morphology at times pick out affixes, and at times pick out bases as the head of the whole word.
Issues in Neurolinguistic Studies of Morphology
Authors: Fiorentino Robert
Published: April 2019

Research in neurolinguistics examines how language is organized and processed in the human brain. The findings from neurolinguistic studies on language can inform our understanding of the basic ingredients of language and the operations they undergo. In the domain of the lexicon, a major debate concerns whether and to what extent the morpheme serves as a basic unit of linguistic representation, and in turn whether and under what circumstances the processing of morphologically complex words involves operations that identify, activate, and combine morpheme-level representations during lexical processing. Alternative models positing some role for morphemes argue that complex words are processed via morphological decomposition and composition in the general case (full-decomposition models), or only under certain circumstances (dual-route models), while other models do not posit a role for morphemes (non-morphological models), instead arguing that complex words are related to their constituents not via morphological identity, but either via associations among whole-word representations or via similarity in formal and/or semantic features. Two main approaches to investigating the role of morphemes from a neurolinguistic perspective are neuropsychology, in which complex word processing is typically investigated in cases of brain insult or neurodegenerative disease, and brain imaging, which makes it possible to examine the temporal dynamics and neuroanatomy of complex word processing as it occurs in the brain. Neurolinguistic studies on morphology have examined whether the processing of complex words involves brain mechanisms that rapidly segment the input into potential morpheme constituents, how and under what circumstances morpheme representations are accessed from the lexicon, and how morphemes are combined to form complex morphosyntactic and morpho-semantic representations. Findings from this literature broadly converge in suggesting a role for morphemes in complex word processing, although questions remain regarding the precise time course by which morphemes are activated, the extent to which morpheme access is constrained by semantic or form properties, as well as regarding the brain mechanisms by which morphemes are ultimately combined into complex representations.
Dynamic Evaluation of Liver Fibrosis to Assess the Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis C Who Achieved Sustained Virologic Response
Authors: Toyoda Hidenori , Tada Toshifumi , Yasuda Satoshi , Mizuno Kazuyuki , Ito Takanori , Kumada Takashi
Published: April 2019

Background

Liver fibrosis is an important risk factor for the development of hepatocellular carcinoma (HCC) after sustained virologic response (SVR) in patients with persistent hepatitis C virus (HCV) infection. However, as the degree of liver fibrosis changes following the eradication of HCV after SVR, it is unclear whether the prediction of HCC development based on liver fibrosis at baseline remains valid.

Methods

In 522 patients who achieved SVR by interferon-based anti-HCV therapy, the Fibrosis-4 Index for Liver Fibrosis (FIB-4 index) was updated annually by recalculation based on laboratory values after SVR. The incidence of HCC was reassessed annually based on the updated FIB-4 index.

Results

The percentage of patients with mild liver fibrosis (FIB-4 index <1.45) increased annually after SVR, whereas the percentage of patients with advanced liver fibrosis (FIB-4 index ≥3.25) decreased. The incidences of HCC based on the FIB-4 index remained constant between the time of SVR and subsequent annual updates. No patients developed HCC after SVR if the FIB-4 index decreased to <1.45.

Conclusions

The FIB-4 index retained its predictive ability for the risk of HCC when recalculated after SVR, despite the decrease in patients with high FIB-4 index values. Dynamic assessment of the FIB-4 index can be useful in the surveillance of HCC after SVR. Patients with a FIB-4 index <1.45 did not develop HCC even by the regression from advanced fibrosis after SVR. Further studies will be necessary to confirm these findings, which may result in a decrease in the number of patients in whom surveillance is required.
Simultaneous multiple organ emboli in a patient with solid organ malignancy: a case report
Authors: Wang Christopher Shing Wen , Hii Isabell , Rahman Atifur
Published: April 2019

Background

Thrombosis is a dangerous complication of cancer. At least 20% of cancer patients are diagnosed with a venous thrombotic event and 1% with an intra-arterial thrombotic event. Here, we present a patient that developed separate thrombi that occurred simultaneously in both the venous and arterial circulation.

Case summary

An 80-year-old woman with a history of recently diagnosed squamous cell lung cancer presented to our institution with an out of hospital cardiac arrest. On arrival, she was found to have an inferior ST-elevation myocardial infarction on electrocardiogram and on examination was found to have right-sided neurological deficits. Computed tomography head and aortogram showed an acute ischaemic stroke and bilateral segmental pulmonary emboli. Coronary angiogram showed thrombotic occlusion distal to the right coronary artery, and the patient underwent aspiration thrombectomy with thrombolysis in myocardial infarction 3 flow established at the end of the procedure. The patient was then transferred to interventional radiology where she had successful clot retrieval of the cerebral thrombus. The patient progressed well and had full neurological recovery 72 h post-presentation. Subsequent transoesophageal echocardiography showed no evidence of a patent foramen ovale or other intracardiac shunt. The patient was prescribed long-term anticoagulant with Clexane.

Discussion

There was suspicion for a deep vein thrombosis with subsequent embolization to the lungs and paradoxical embolization through an intracardiac shunt. However, no such defect was detected and it appears that the patient did develop thrombi in the arterial and venous system separately. This case highlights the prothrombotic state of malignancy, with the patient suffering from multiple separate life-threatening thrombi.
Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade
Authors: Christersdottir Tinna , Pirault John , Gisterå Anton , Bergman Otto , Gallina Alessandro L , Baumgartner Roland , Lundberg Anna M , Eriksson Per , Yan Zhong-Qun , Paulsson-Berne Gabrielle , Hansson Göran K , Olofsson Peder S , Halle Martin
Published: April 2019

Aims

Radiotherapy-induced cardiovascular disease is an emerging problem in a growing population of cancer survivors where traditional treatments, such as anti-platelet and lipid-lowering drugs, have limited benefits. The aim of the study was to investigate vascular inflammatory patterns in human cancer survivors, replicate the findings in an animal model, and evaluate whether interleukin-1 (IL-1) inhibition could be a potential treatment.

Methods and results

Irradiated human arterial biopsies were collected during microvascular autologous free tissue transfer for cancer reconstruction and compared with non-irradiated arteries from the same patient. A mouse model was used to study the effects of the IL-1 receptor antagonist, anakinra, on localized radiation-induced vascular inflammation. We observed significant induction of genes associated with inflammasome biology in whole transcriptome analysis of irradiated arteries, a finding supported by elevated protein levels in irradiated arteries of both, pro-caspase and caspase-1. mRNA levels of inflammasome associated chemokines CCL2, CCL5 together with the adhesion molecule VCAM1, were elevated in human irradiated arteries as was the number of infiltrating macrophages. A similar pattern was reproduced in Apoe−/− mouse 10 weeks after localized chest irradiation with 14 Gy. Treatment with anakinra in irradiated mice significantly reduced Ccl2 and Ccl5 mRNA levels and expression of I-Ab.

Conclusion

Anakinra, administered directly after radiation exposure for 2 weeks, ameliorated radiation induced sustained expression of inflammatory mediators in mice. Further studies are needed to evaluate IL-1 blockade as a treatment of radiotherapy-induced vascular disease in a clinical setting.
Fine-scale diversity patterns in belowground microbial communities are consistent across kingdoms
Authors: Aas Anders Bjørnsgaard , Andrew Carrie J , Blaalid Rakel , Vik Unni , Kauserud Håvard , Davey Marie L
Published: April 2019

The belowground environment is heterogeneous and complex at fine spatial scales. Physical structures, biotic components and abiotic conditions create a patchwork mosaic of potential niches for microbes. Questions remain about mechanisms and patterns of community assembly belowground, including: Do fungal and bacterial communities assemble differently? How do microbes reach the roots of host plants? Within a 4 m2 plot in alpine vegetation, high throughput sequencing of the 16S (bacteria) and ITS1 (fungal) ribosomal RNA genes was used to characterise microbial community composition in roots and adjacent soil of a viviparous host plant (Bistorta vivipara). At fine spatial scales, beta-diversity patterns in belowground bacterial and fungal communities were consistent, although compositional change was greater in bacteria than fungi. Spatial structure and distance-decay relationships were also similar for bacteria and fungi, with significant spatial structure detected at <50 cm among root- but not soil-associated microbes. Recruitment of root microbes from the soil community appeared limited at this sampling and sequencing depth. Possible explanations for this include recruitment from low-abundance populations of soil microbes, active recruitment from neighbouring plants and/or vertical transmission of symbionts to new clones, suggesting varied methods of microbial community assembly for viviparous plants. Our results suggest that even at relatively small spatial scales, deterministic processes play a significant role in belowground microbial community structure and assembly.