bluuebunny/crossref_metadata_2025 huggingface dataset:
Кам’янець-Подільський державний університет у період становлення радянської влади: зміна структурних форм
Authors: Адамський Віктор
Published: August 2024

The article analyzes the reorganization of university education in Ukraine on the example of Kamianets-Podilskyi National University during the period of Bolshevik rule. The author examines the transformations that took place at the university under the influence of Soviet educational reforms, starting in 1919, when the university first faced the Soviet authorities. Particular attention is paid to the reorganization processes that lasted until the early 1920s, including the transformation of the university into the Academy of Theoretical Knowledge and the creation of new faculties. The author also examines the impact of Soviet policy on organizational changes at the university, which were part of broader processes aimed at integrating higher education into a new system of education that met the objectives of socialist construction.
Waiting, planning, and tricking the future
Authors: Aasmäe Kalev
Published: August 2024

This article explores the aftermath of the criminalization of residential squatting in England and Wales in 2012. It draws on ethnography among squatters in South East London, analyzing their strategies for resisting the uncertainty of eviction, and engages critically with the concepts of capitalist time and temporal agency. As the pressure of time-specific laws protecting the interests of the owners of empty properties creates an environment of ever-present uncertainty and insecurity, the squatters perform specific future-oriented activities aiming to resist and overcome the external capitalist timeframes imposed on them. By highlighting certain practices such as decoration, furniture building, information gathering, and waiting, this article explores the future-oriented timescapes of squatting and the manipulation of linear temporal processes embedded in the logics of capitalism.
Effectiveness of May Grunwald Giemsa staining on tissues fixed with sugar cane molasses
Authors: Kuloğlu Hatice Yaren , Yahyazadeh Ahmad
Published: August 2024

Formaldehyde is a reactive chemical that reacts randomly with various cellular elements. This substance, which is also found in the natural structure of the organism, is used in many areas, from the industry to household materials, from the production of coatings in dentistry to the fixation of cadavers in laboratories. Formaldehyde is commonly used in laboratories for fixation of tissues. In this study, the staining properties of tissues fixed with low-cost sugar cane molasses, which is one of the natural sugars and organically produced in Turkey, shown by May Grunwald Giemsa staining method were compared with those of tissues fixed with buffered formol-saline. As a result, intense maceration was observed in the skin and small intestines. Considering the chromatin distribution, nucleus separation and cytoplasm staining in other tissues (liver, spleen, kidney, testis, large intestine, brain, cerebellum and lung), tissues fixed with sugarcane molasses showed similar properties to tissues fixed with buffered formal-saline.
Can Tumor Recurrence Be Predicted by Magnetic Resonance Imaging Findings Before Microwave Ablation in Patients with Hepatocellular Carcinoma?
Authors: Özdemir Mustafa
Published: August 2024

Purpose: Hepatocellular carcinoma (HCC) is a common cancer. The primary treatment is surgery or liver transplantation. Percutaneous ablation techniques constitute the primary treatment in patients who are not suitable for surgery. Although it gives successful results, some studies report a recurrence rate of up to 50%. This study aimed to obtain an idea about the possibility of possible recurrence by evaluating the lesion characteristics in the pre-procedure MRI images of patients with and without recurrence.
Methods: Forty-eight patients who underwent microwave ablation for HCC in our center between 2018 and 2021 were included in the study. Lesion size, presence of peripheral enhancement, arterial contrast enhancement, and T2 signal characteristics were evaluated on MRI. Subsequently, the relationship of these features with tumor recurrence was evaluated.
Results: When lesions with and without recurrence were compared during follow-up, it was shown that the risk of recurrence was high in patients with lesion sizes larger than 3 cm and in lesions showing peripheral contrast enhancement (p 0.036 and p 0.021, respectively).
Conclusion: Since there is a high probability of recurrence after ablation in HCCs larger than 3 cm and showing peripheral contrast, close follow-up will be beneficial.
El propósito de la muralla de Adriano según Collingwood: una ilustración de la lógica de pregunta y respuesta
Authors:   Universidad de Guadalajara, Leal Carretero Fernando
Published: August 2024

In his autobiography, Collingwood illustrates what he calls “the logic of question and answer” with several examples, one of which is his solution to the question of the purpose of the wall that the Romans built roughly between present-day England and Scotland under Hadrian and later emperors. The purpose of this paper is to present an annotated translation of Collingwood’s article in which he sets out that solution. By carefully analyzing his argumentation, it is possible to show how the logic of question and answer works in detail. Given the place that Collingwood's works occupy in the curriculum of undergraduate students of history in this country, this way of explaining the logic of question and answer seems to be the most suitable for students to gain access to a powerful heuristic and hermeneutic tool both to better understand historians’ arguments and to better construct their own.
Effect of principal’s feedback on online teaching during COVID-19 pandemic
Authors: Patel Nilesh Kumar , Kukreja Amit
Published: August 2024

The main purpose of the study was to explore the effect of principal’s feedback on Online Teaching during Covid - 19 Pandemic. Objectives of the study were to study the effect of Principal’s feedback on Teaching effectiveness of Primary and Secondary school teachers by considering (1) preteaching effectiveness, (2) Teacher morale & (3) Job satisfaction as covariate. Null hypotheses were formulated for testing. The Nonequivalent control group design given by Stanley and Campbell (1963) was used for this experimental study. Purposive sampling technique was used due to the pandemic year. There were 65 primary and Secondary school teachers and 4 Principals out of which 34 teachers were randomly assigned in the treatment group and 31 teachers were randomly treated in the Control group. Data were collected by standardized scales and questionnaire. The one way Analysis of Covariance was used for data analysis purpose. It was revealed in the study that the Principal’s feedback provided to the school teachers was effective on increasing Teaching effectiveness. The study included the implications for the Students, teachers, School Principals and the School Managements.
Audit market concentration in an emerging economy
Authors: Dabor Alexander Olawumi , Wilson Osarodion Famous , Joy Osemwegie-Ero
Published: August 2024

The aimed of this study is to ascertain the relationship between audit attributes and audit quality in an emerging economy. The study deliberately cover the post-Enron era and postaudit reforms era decipher the activities of audit after the demise of Enron.  This study used selected quoted firms in Nigeria for a period of sixteen (16) years, 2006 – 2021. The models were built based on a study of extant literature, GOA and audit reforms. Ordinary least square econometric technique was employed to analyze data extracted from a secondary source. The outcomes of this study revealed that Audit client size has positive relationship with audit quality. The result further revealed that audit client complexity has negative relationship with audit quality. Finally, the result revealed that   audit client business risk has no significant relationship with taudit quality. This study recommended that Alternative appointment processes for auditors, e.g. involving shareholder panels, or appointment by regulator.
Gender equality: Progress, and challenges in european society
Authors: Bajraktari Halim , Faiku Muharem , Qatani Valeri
Published: August 2024

This article explores the dynamics of gender equality in European society, focusing on both the progress made and the ongoing challenges facing European society. The study investigates the impact of legal frameworks and rights in shaping equal opportunities for the whole of European society by excluding the possibility of differences on different grounds. Furthermore, the study assesses the impact of institutional commitment to gender equality within European legal and social contexts. The analysis covers a long-term period by examining the legal infrastructure related to gender equality: a model case of some countries in Europe. Through our findings, we will reflect the impact of the factors that have meanwhile combined the phenomenon of inequality in European society. Regarding institutional commitment, we will highlight the effectiveness of intergovernmental policies, proving this hypothesis through statistics that show the position of women in various fields.
Hypersexuality in mental health: Understanding, diagnosing, and treating the uncharted territory
Authors: Rath Omkar , Basheeruddin Mohd
Published: August 2024

In the field of mental health, hypersexuality—which is defined by an uncontrollably high and disturbing level of sexual behavior—presents difficulties for both diagnosis and therapy. This paper examines the complex nature of hypersexuality, recognizing that it may represent a main problem or a symptom of underlying mental and neurological disorders. A variety of physiological and psychological issues, including mood disorders, brain damage, and dementia, are taken into account in the diagnostic landscape. The review explores thesymptoms of hypersexuality and relates it to diseases like dementia and borderline personality disorder. Additionally, the complex interaction between depression and hypersexuality is examined, providing insight into the possibility of using hypersexuality as a coping mechanism for depressed symptoms. The research highlights how less evident data is available to support treatment options for hypersexuality. Main treatment aspect, psychotherapy is usually combined with medicines. Broad range of available therapies emphasizes the need of personalized strategies based on the specific needs of individual patient. The article also highlights the substantial effects of hypersexuality on both personal and professional life of patient. The need for all-encompassing and individualized treatment plans is required for HS. The lack of definitive data suggests how important it is to conduct further research in this area to improve our knowledge to deal with the issues related to hypersexuality.
Role of magnesium sulfate in pregnancy: A comprehensive review of benefits and risks
Authors: Wanjari Mayur , Late Sampada , Umate Seema , Choudhary Minakshi , Munjewar Pratiksha , Lohakare Tejaswee , Sharma Ranjana , Singh Seema , Gawai Jaya , Taksande Vaishali , Mendhe Deeplata , Meghe Abhyuday
Published: August 2024

Magnesium sulfate is a versatile therapeutic agent in maternal-fetal medicine, and its use during pregnancy has led to various clinical scenarios. This comprehensive review examines the multifaceted role of magnesium sulfate, addressing its benefits and potential risks. The mineral compound is limited for its efficacy in preventing and managing preeclampsia and eclampsia, providing neuroprotection for preterm infants, delaying preterm labor, and offering potential advantages in maternal and fetal health. However, its administration is complex, encompassing a range of maternal and fetal side effects and long-term implications. The decision to utilize magnesium sulfate during pregnancy necessitates a balanced assessment of its advantages and disadvantages, underscored by patient-centered care and shared decision-making. Future research and practice guidelines include pursuing personalized medicine, optimal dosing and administration, long-term follow-up, global health initiatives, and ethical considerations. The evolving landscape of research and emerging insights will continue to enhance maternal care and contribute to improved health outcomes for pregnant women and their infants.
Constitutional and municipal law: Analysing constitutions and their societal implications
Authors: Sergiienko Larysa , Pugachov Mykola , Ihnatiuk Oleh , Serohina Nataliia , Panchyshyn Ruslan
Published: August 2024

The present study scrutinizes the societal implications of constitutions and their significance within both national and international frameworks. The authors undertakes an exploration of the principles underlying constitutional law, delving into the categorization of constitutions based on state structures and political regimes. Additionally, the article explores instances of constitutions from diverse nations, shedding light on their consequential effects on society. Emphasis is placed on a meticulous examination of constitutional structures and their pivotal contribution to the configuration of legal and socio-cultural landscapes. The examination of constituent elements within constitutions enables the illumination of their crucial significance in shaping the legal and socio-cultural fabric of society. Special consideration is directed towards international dimensions, with a specific focus on the impact of preambles in shaping national identity on the global stage. The article systematically investigates the significance of procedures for constitutional amendments, emphasizing their role in fostering stability and facilitating adaptation to prevailing global trends. The purpose of this study is to conduct a comprehensive analysis of the constitution's influence on society, aiming to identify the pivotal components within the constitutional structure that exert the most significant impact on societal development. The primary object of investigation encompasses constitutional documents from diverse countries. This includes a thorough examination of their preambles, core provisions, sections concerning human rights and freedoms, power structures, and an exploration of the international context within which these constitutions operate. The outcomes of this research can function as a crucial resource for human rights organizations, legislative bodies, and constitutional commissions involved in the formulation and amendment of constitutional documents. Moreover, the study creates avenues for additional comparative analyses, facilitating an in-depth exploration of the diverse constituencies across countries and their repercussions on societies within the international sphere.
A bibliometric review of sustainability and firm performance
Authors: Marchan Hannibal George
Published: August 2024

What is the past, present and future trajectories of sustainability and firm performance? The study identified seminal works, current and future trends relevant to sustainability and firm performance. The research employed bibliometric analysis tools such as co-citation, bibliographic coupling, and co-occurrence analysis combined with enrichment tools. Utilizing a dataset that spanned from 1998 to 2023, it used Biblioshiny and analyzed 735 articles from Scopus. The research results showed a growth rate of 23 percent and an average of 37 citations per article.   The research established stakeholder theory and theory of the firm as foundational pillar and latest developments focused on finance, corporate social responsibility, environmental assessment, and sustainability. Emerging trends involved sustainability performance, disclosures, internal factors, sustainability and firm performance, corporate social responsibility and governance, sustainability reporting and stakeholder engagement, and costs. Researchers and practitioners can utilize these findings to direct their work and contribute to the ongoing discourse in sustainability and firm performance research.
Critical factors influencing accounting firm management (AFM) satisfaction with accounting undergraduates: A review and conceptual framework
Authors: Hu Guojing , Muhamad Haslinah , Mustafa Hasri , Liu Man
Published: August 2024

In the recruitment market, accounting employers prioritize the competency of graduates by developing policies to ensure their satisfaction. However, since accounting firms are the primary potential employers for accounting undergraduates, it is essential to investigate the satisfaction of accounting firm management (AFM) with the competency of graduates. Therefore, this study integrates human capital theory (HCT) and expectancy disconfirmation theory (EDT), considering the competency of accounting undergraduates as human capital, which serves as a key factor in assessing AFM satisfaction. Subsequently, the study introduces variables and path relationships derived from the European Customer Satisfaction Index (ECSI), outlining four key constructs: AFM expectation, AFM perceived quality, AFM perceived value, and AFM satisfaction. Previous research has shown that the application of the ECSI has expanded to the higher education field for measuring student satisfaction. Accordingly, in the context of accounting education, this study considers AFM to be the primary client and views the competency of accounting undergraduates as the product or service provided to the client. This study provides an overview of the previous theoretical and empirical literature and develops a conceptual framework aimed at assessing the factors influencing the satisfaction of accounting undergraduates with AFM. Additionally, it addresses gaps in the previous literature, laying the foundation for future research.
Tourism risk analysis and mitigation: Strategies for managing risks in a dynamic tourism environment
Authors: Leonov Yaroslav , Parubets Oleg , Portnoi Yevhenii , Zaloha Zinoviia , Sukhai Olha
Published: August 2024

Tourism is interconnected with other industries and brings additional benefits to both the European economy and Ukraine in general. However, it also depends on external and internal factors and is the first to react to their changes. The article describes and uses a strategy for managing the risks posed by the fast-changing tourism market, where every second trip for travel purposes goes to EU countries. The EU countries comprise 50% of global tourism, while outbound tourism from European countries is almost 48% of all outbound trips and tourism activities worldwide. The COVID-19 pandemic had a severe impact on the tourism sector of many countries, leading to significant changes and negative consequences. However, the tourism industry is dynamic and constantly evolving, responding to any changes and demands. Therefore, the relevance of this study lies in exploring further ways to develop tourism in the European tourism macroregion, taking into account the impact of the COVID-19 pandemic. The unprecedented pace of transformation has affected the management system of tourism enterprises. Travel companies must respond quickly to constantly changing environmental conditions to protect their reputation and financial stability. Therefore, there is a real need to create a modern, comprehensive risk management system for tourism companies. Risks cannot be eliminated, yet any business owner who cares about the success of their business must investigate possible adverse factors affecting their profits and take action to reduce them. Risk management serves this purpose.
A bibliometric study on sustainable water management research evidence from the Scopus database
Authors: Raman S. A. , Rajan C. R. Sundara
Published: August 2024

The recognition of the importance of sustainable water management has increased due to the emergence and strong focus on the Sustainable Development Goal. Consequently, there has been progress in understanding various disciplines, specifically aimed at addressing concerns related to water consumption and pressure, sustainable water generation, and the sustainable administration of water resources. Therefore, the aim of this article is to bridge this gap by using a bibliometric approach to analyze the number of contributions and their impact on the literature regarding awareness of sustainable water management in the field of management sciences. This study seeks to identify areas of research that can be further explored to improve the literature on this emerging subject through a critical analysis of articles obtained from the Scopus database. It is important to note that sustainable water management and awareness are two interconnected and crucial domains that play a vital role in ensuring the sustainable use of water resources and promoting public health. The uniqueness of this study is of great importance for scholars, researchers, and policymakers in the field of management sciences, as it presents a comprehensive research agenda on the awareness of sustainable water management.
Implication of human resource management practices in SMEs in India
Authors: Sharma Apurva , Manoj Kumar Meet
Published: August 2024

This descriptive study examines the implementation of HRM practices in small and medium enterprises (SMEs) in RIICO industrial areas in Neemrana and Jaipur. While in large organizations, human resource management practices are well established in a formal way, they tend to be informal in SMEs. Despite the significance of HRM practices for growth, there is a lack of consistent implementation in SMEs. The study utilizes a case method approach, analyzing data from 28 SMEs, to gain insights into the perceptions of HR professionals responsible for implementing HRM practices. The findings of this study can serve as a valuable resource for developing future guidelines and recommendations for HR practices in SMEs. Understanding the challenges and perceptions of HR professionals in SMEs. This study aims to contribute to formalizing and improving HRM practices in the SME sector.
Exploring ethical implications in hospital management: Aligning business objectives with patient care ethics
Authors: Patne Shruti , Kanyal Deepika
Published: August 2024

Hospital management is a complex process that involves balancing operational efficiency, financial sustainability, and patient care. As healthcare institutions operate within commercial frameworks, the intersection of business objectives with patient care ethics becomes a significant concern. Ethical considerations in hospital management include resource allocation, stakeholder relationships, conflicts of interest management, and decision-making processes. Balancing profitability demands with ethical obligations poses challenges for administrators, necessitating a comprehensive understanding of managerial practices. Hospitals must balance business objectives with patient care ethics, ensuring ethical practices in resource allocation, managing relationships with multiple stakeholders, and ensuring patient autonomy, beneficence, nonmaleficence, and justice. As hospitals operate within commercial entities, it is crucial to ensure that profitability does not compromise patient well-being or erode trust in healthcare institutions. Healthcare professionals must be aware of the ethical implications of dual relationships with clients, resource allocation, and other ethical decisions. Collaborating scholars, policymakers, and healthcare practitioners can promote ethical excellence in hospital management, enhance patient care outcomes and advancing healthcare ethics.
Breast cancer treatment with coenzyme Q10 (CoQ10)
Authors: Shende Pratiksha V. , Mude Gaurav S. , Amipara Abhishek G.
Published: August 2024

Coenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated. CoQ10 has shown immune-boosting effects in clinical studies, encouraging researchers to look into its possible influence on breast cancer. Several research have looked at the link between CoQ10 and breast Coenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated. CoQ10 has shown immune-boosting effects in clinical studies, encouraging researchers to look into its possible influence on breast cancer. Several research have looked at the link between CoQ10 and breast cancer, focusing on its biological effects such as cytochrome c release and subsequent radical production. CoQ10 supplementation is commonly used by cancer patients to alleviate a perceived CoQ10 deficit associated with treatment-related toxicity. Notably, evidence shows that CoQ10 may be connected to lower tocopherol levels increasing the risk of breast cancer. However, bigger sample sizes, longer follow-up periods, and a better knowledge of the physiological role of circulating CoQ10 are required for a thorough assessment of CoQ10's possible role in breast cancer etiology. Antibacterial medications, therapy-induced adverse effects, and oxidative stress all have an impact on chemotherapy-related problems. Although CoQ10 has shown potential as an alternative breast cancer treatment, it is crucial to highlight that existing standard therapies, such as chemotherapy, radiation therapy, and hormone therapy, are not without their limitations. and targeted therapies are all options. Remain the cornerstone of breast cancer care. Always seek the most current and trustworthy information about breast cancer therapy from medical specialists.
Exploring trends and dynamics in women’s entrepreneurship research: A bibliometric analysis of survey questionnaires and emerging themes
Authors: Bedaduri Ramamurthy , Mamilla Rajesh
Published: August 2024

Women’s entrepreneurship plays a pivotal role in societal progress and economic development, fostering diversity, innovation, and inclusive growth. This review paper examines the significance of women entrepreneurship research through a multifaceted lens, encompassing surveys, questionnaires, and bibliometric analyses, spanning from 1985 to 2023. By utilizing the Scopus database and employing bibliometric analysis with VOSviewer, this study investigated trends, prominent authors, contributing institutions, and funding sources. While existing research has made progress, significant gaps remain, particularly in understanding cultural and socioeconomic contexts. By utilizing bibliometric analysis, this study identifies prominent authors, research areas, source institutions, nations, and funding sponsors contributing to the field. Moreover, it identifies emerging themes such as access to finance, post-COVID-19 entrepreneurship, rural and youth entrepreneurship, and human capital sustainability. By elucidating these factors, this research offers insights for policymakers, practitioners, and researchers to enhance support and promote women’s entrepreneurship globally.
Wisdom behind understanding cleft lip and palate
Authors: Gandhewar Aditi Mahesh , Hande Alka
Published: August 2024

In medicine, one of the most prevalent birth defects is clefts. This article describes the prevalence of clefts among different racial groups and geographic areas. According to research, the cleft incidence is primarily higher among Native Americans and Asians. The exact cause of clefts is unknown, but its incidence is influenced by various environmental and genetic factors. As shown in this article from an embryological standpoint, prenatal care during the first trimester is essential to prevent clefts. It is widely accepted that poorer economic levels have higher rates of cleft prevalence than other classes. Although solid relationships have been found through investigations, it has not been established beyond a doubt. The main goal of this article is to encourage doctors to raise awareness and educate parents from all socioeconomic backgrounds about the risk factors for cleft lip and palate before conception. This aims to prevent both the physical effects and the psychological trauma for the child. The article also discusses how cleft prevention and effective care can positively impact the mental and physical health of both patients and their families. Cleft treatment involves a multidisciplinary strategy.
IMPLEMENTASI MARKET DAY UNTUK MENINGKATKAN NUMERASI DAN KEMANDIRIAN SISWA SEKOLAH DASAR MELALUI KM6
Authors: Septi Sami Damiana Theresia , Purnomo Sapto
Published: August 2024

: Program kampus mengajar yang menjadi salah satu inisiatif terkemuka dalam mendorong peningkatan kualitas pendidikan di negeri ini telah memberikan kontribusi yang luar biasa. Dalam kampus mengajar angkatan 6 ini menawarkan kesempatan untuk menerapkan inovasi pendidikan khususnya melalui implementasi Market Day. Dari sini rumusan masalahnya adalah (1) Bagaimana program Market Day diimplementasikan dalam program kampus mengajar? (2) Bagaimana meningkatkan keterampilan numerasi dan kemandirian siswa melalui Market Day? Tujuan penelitian ini adalah untuk (1) Mendeskripsikan pelaksanaan Market Day di kelas dalam program kampus mengajar (2) Mendeskripsikan peningkatan kemandirian siswa melalui Market Day. Metode yang digunakan dalam program Market Day ini yaitu pendekatan kualitatif. Hasil penelitian menunjukkan bahwa pelaksanaan Market Day sebagai salah satu program di Sekolah  Dasar  dapat  efektif  dalam  menanamkan  karakter  jiwa  dan  mental  wirausaha  pada  siswa. Melalui  kegiatan  jual  beli  dalam  Market  Day,  siswa  dapat  mengembangkan  beberapa  karakteristik wirausaha yang penting. Kegiatan Market Day dapat membangun karakter kewirausahaan kepada peserta didik diantaranya kreatif, inovatif, dan berorientasi pada masa depan, berani mengambil resiko, percaya diri, bertanggung jawab dan peduli, serta pandai mengelola keuangan. Karakter kewirausahaan ini dapat menumbuhkan jiwa kewirausahaan yang memotivasi minat peserta didik untuk menjadi seorang wirausahawan.
SOSIALISASI PENTINGNYA PEMBELAJARAN ETIKA UNTUK MEMBENTUK KARAKTER SISWA DI SDN 024 SAMARINDA UTARA
Authors: Afdal Afdal , Mayasari Renni , Steven Andi , Balan Viktor
Published: August 2024

Abstrak: Pengabdian ini bertujuan untuk menggambarkan pentingnya pembelajaran etika untuk membentuk karakter sopan santun siswa SDN 024 Samarinda Utara.peserta pada sosialisasi ini adalah guru, kepala Sekolah, orang tua siswa dan siswa itu sendiri. Kegiatan ini dilakukan dengan melalui forum diskusi dan tanya jawab.Hasil menunjukan bahwa pembentukan karakter dan etika siswa sangatlah penting ditanamkan sejak dini, peran wali kelas dan orang tua juga sangat berpengaruh penting dalam maksimalkan pembentukan karakter dan etika siswa. Hal ini didukung dari hasil diskusi dan wawancara besama guru yang mengungkapkan bahwa perlu diingat pembentukan karakter dan etika siswa tidak dapat berkembang jika hanya di sekolah saja aka tetapi keluarga juga harus mengambil peran mengembangkan karakter anak, keluarga merupakan faktor penting dalam membentuk karakter siswa. kami memandang bahwa pendidikan karakter dan etika sangatlah berpengaruh penting atas prestasi siswa, dengan menyalurkan setiap nilai-nilai pendidikan karakter dan etika dalam proses pembelajaran siswa dengan perlahan akan memahami tentang pentingnya etika dalam kehidupan. Kata Kunci : Karakter Siswa, Pembelajaran Etika, Sosialisasi
PEMBUATAN PAKAN ALTERNATIF DENGAN MEMANFAATKAN BAHAN DARI POTENSI LOKAL DALAM PENINGKATAN PRODUKTIVITAS PERIKANAN
Authors: Julung Hendrikus , Ege Benediktus , Bustami Yakobus
Published: August 2024

Abstrak:Melimpahnya sumber daya alam sebagai potensi lokal berupa limbah rumah tangga, limbah pertanian dan tumbuhan yang dapat dijadikan bahan pembuatan pakan ikan untuk memenuhi kebutuhan rumah tangga dan meningkatkan kesejahteraan masyarakat. Potensi tersebut belum dikelola dengan baik karena masyarakat kurang mengetahui nilai manfaatnya serta kurangan pengetahuan dan keterampilan untuk mengembangkan usaha perikanan dan pembuatan pakan alternatif dari bahan baku lokal, padahal peluang usahanya menjanjikan untuk meningkatkan pendapatan dan ekonomi masyarakat. Tujuan PKM ini adalah memberikan wawasan dan pengetahuan serta keterampilan kepada masyarakat tentang sumber daya lokal yang dapat dikelola menjadi pakan alternatif bagi ikan. Metode PKM yang digunakan berupa penyuluhan dan pelatihan. Hasil PKM ini bahan alternatif pembuatan pakan dari limbah rumah tangga seperti; air cucian beras, limbah sayuran, limbah buah-buahan dan dari limbah ertanian berupa dedak halus dari sekam serta limbah industri dan pasar seperti kepala ikan teri dan ampas tahu. Tumbuh-tumbuhan yang dapat dijadikan campuran bahan pakan seperti; Umbi-umbian, rebung, bongol pisang, kelor, kelapa, eceng gondok.  Kata Kunci: Pakan Alternatif, Potensi Lokal, Perikanan.
Fleisch- und Milchersatzprodukte – besser für Gesundheit und Umwelt?
Authors: Mehner Eric , Ehlers Melf-Hinrich , Herrmann Moritz , Höchli Bettina , Holenweger Geraldine , Mann Stefan , Messner Claude , Nemecek Thomas , Reguant Closa Alba , Schäfer Otto , Stämpfli Aline , Walther Barbara , Douziech Mélanie
Published: August 2024

In den letzten Jahren sind zunehmend Lebensmittel auf den Markt gekommen, die als Ersatz für tierische Produkte gedacht sind. Dies ist auch mit dem Ziel geschehen, die Nachhaltigkeit der Ernährung zu verbessern und die Gesundheit positiv zu beeinflussen. Es stellt sich jedoch die Frage, ob diese Alternativ- oder Ersatzprodukte tatsächlich dazu in der Lage sind. Die interdisziplinäre Studie zeigt Chancen und Risiken auf beim Ersatz von Fleisch und Milchprodukten durch Alternativen, die meist aus pflanzlichen Rohstoffen hergestellt werden. Dabei stehen die Nährstoffversorgung und die Umweltwirkungen im Fokus. Ergänzend wird dargelegt, wie Konsumentinnen und Konsumenten die Ersatzprodukte beurteilen und wie diese aus ethischer Sicht zu bewerten sind. Ferner werden die rechtlichen Rahmenbedingungen analysiert sowie die Möglichkeiten für die Landwirtschaft in der Schweiz abgeschätzt, Rohstoffe für die Produktion von Alternativprodukten bereitzustellen. Abschliessend werden Empfehlungen präsentiert, die an die Konsumentinnen und Konsumenten, die verarbeitende Industrie, Fachgesellschaften sowie an Politik und Verwaltung gerichtet sind.
Comparative analysis of features and classification techniques in breast cancer detection for Biglycan biomarker images
Authors: Ma’touq Jumana , Alnuman Nasim
Published: August 2024

BACKGROUND:

Breast cancer (BC) is considered the world’s most prevalent cancer. Early diagnosis of BC enables patients to receive better care and treatment, hence lowering patient mortality rates. Breast lesion identification and classification are challenging even for experienced radiologists due to the complexity of breast tissue and variations in lesion presentations.

OBJECTIVE:

This work aims to investigate appropriate features and classification techniques for accurate breast cancer detection in 336 Biglycan biomarker images.

METHODS:

The Biglycan biomarker images were retrieved from the Mendeley Data website (Repository name: Biglycan breast cancer dataset). Five features were extracted and compared based on shape characteristics (i.e., Harris Points and Minimum Eigenvalue (MinEigen) Points), frequency domain characteristics (i.e., The Two-dimensional Fourier Transform and the Wavelet Transform), and statistical characteristics (i.e., histogram). Six different commonly used classification algorithms were used; i.e., K-nearest neighbours (k-NN), Naïve Bayes (NB), Pseudo-Linear Discriminate Analysis (pl-DA), Support Vector Machine (SVM), Decision Tree (DT), and Random Forest (RF).

RESULTS:

The histogram of greyscale images showed the best performance for the k-NN (97.6%), SVM (95.8%), and RF (95.3%) classifiers. Additionally, among the five features, the greyscale histogram feature achieved the best accuracy in all classifiers with a maximum accuracy of 97.6%, while the wavelet feature provided a promising accuracy in most classifiers (up to 94.6%).

CONCLUSION:

Machine learning demonstrates high accuracy in estimating cancer and such technology can assist doctors in the analysis of routine medical images and biopsy samples to improve early diagnosis and risk stratification.
A high-level simulator for Network-on-Chip
Authors: Paris Paulo Cesar Donizeti , Pedrino Emerson Carlos
Published: August 2024

This study presents a high-level simulator for Network-on-Chip (NoC), designed for many-core architectures, and integrated with the PlatEMO platform. The motivation for developing this tool arose from the need to evaluate the behavior of application mapping algorithms and the routing, both aspects are essential in the implementation and design of NoC architectures. This analysis underscored the importance of having effective NoC simulators as tools that allow for studying and comparing various network technologies while ensuring a controlled simulation environment. During this investigation and evaluation, some simulators, such as Noxim, NoCTweak, and NoCmap, among others, offered configurable parameters for application traffic, options to synthetically define topology and packet traffic patterns. Additionally, they include mapping options that optimize latency and energy consumption, routing algorithms, technological settings such as the CMOS process, and measurement options for evaluating performance metrics such as throughput and power usage. However, while these simulators meet detailed technical demands, they are mostly restricted to analyzing the low-level elements of the architecture, thus hindering quick and easy under- standing for non-specialists. This insight underscored the challenge in developing a tool that balances detailed analysis with a comprehensive learning perspective, considering the specific restrictions of each simulator analyzed. Experiments demonstrated the proposed simulator efficacy in handling algorithms like GA, PSO, and SA variant, and, surprisingly, revealed limitations of the XY algorithm in Mesh topologies, indicating the need for further investigation to confirm these findings. Future work will expand the simulator functionalities, incorporating a broader range of algorithms and performance metrics, to establish it as an indispensable tool for research and development in NoCs.
Long-Term Safety of Gantenerumab in Participants with Alzheimer’s Disease: A Phase III, Double-Blind, and Open-Label Extension Study (Marguerite RoAD)
Authors: Neve Anuja , Das Bibha , Wojtowicz Jakub , Huang Zhiyue , Bullain Szofia , Watkin Michelle , Lott Dominik , Bittner Tobias , Delmar Paul , Klein Gregory , Hofmann Carsten , Kerchner Geoffrey A. , Smith Janice , Baudler Monika , Fontoura Paulo , Doody Rachelle S.
Published: August 2024

Background:

Gantenerumab is an anti-amyloid-β immunoglobulin G1 monoclonal antibody for subcutaneous (SC) administration. The efficacy and safety of low-dose (105 mg or 225 mg) gantenerumab were investigated in Marguerite RoAD (MR; NCT02051608), a Phase III, double-blind (DB), placebo-controlled study in participants with mild Alzheimer’s disease (AD) dementia. Following a preplanned futility analysis of the SCarlet RoAD study (NCT01224106), MR was converted into an open-label extension (OLE).

Objective:

The DB study aimed to assess the efficacy of gantenerumab compared with placebo from baseline to Week 104 in participants with mild AD dementia. Following conversion to an OLE, this objective became exploratory, as the OLE assessed the long-term safety and tolerability of SC gantenerumab at doses of up to 1,200 mg every 4 weeks (Q4W) in OLE participants.

Methods:

Eligible DB study participants were offered the opportunity to receive gantenerumab up-titrated to 1,200 mg Q4W. Safety and tolerability were assessed using magnetic resonance imaging (MRI), physical and neurologic examinations, and adverse event monitoring.

Results:

Overall, 225 participants were rolled over from the DB part of MR and received ≥1 gantenerumab dose in the OLE. The median treatment duration was 123 weeks. Fifty-nine (26.2%) and 41 (18.2%) participants had amyloid-related imaging abnormality (ARIA)-edema and ARIA-hemorrhage MRI findings, respectively. ARIA findings were manageable with MRI monitoring and dose intervention; most were asymptomatic. There were no unexpected safety findings.

Conclusions:

SC gantenerumab at doses of up to 1,200 mg Q4W were well tolerated in participants with mild AD dementia.
Trailblazer: A proactive caching, blockchain, minimum content retrieval latency, and energy cost-aware resource and job orchestration scheme for publisher-subscriber based 6G ICN services
Authors: Chowdhury Mahfuzulhoq
Published: August 2024

With the rise of information-centric networks (ICN), the user can access the caching content from nearby caching nodes rather than the remote content server through in-network caching facilities. The existing articles did not look into minimum caching content retrieval latency, user energy consumption, user financial cost, and maximum service provider profit-aware proper resource orchestration and job scheduling policies all at once, taking into account multiple publishers and subscriber-based caching jobs, blockchain, user-owned and service provider cache, pre-caching, neighbor collaboration, and available resources. To suppress these challenges, this article offers a proactive pre-caching, collaboration, blockchain, minimum latency-aware resource, and job scheduling policy for 6G ICN services that takes into account publishers’ and subscribers’ caching job requests, user-owned and service provider cache, available resources, and deadline. The experimental results visualized that at least 16% content retrieval delay, 66% energy, and 22% service provider profit gain are attained in the proposed scheme over the existing techniques.
Cardiac Involvement in LAMA2-Related Muscular Dystrophy and SELENON-Related Congenital Myopathy: A Case Series
Authors: Bouman Karlijn , van den Heuvel Frederik M.A. , Evertz Reinder , Boesaard Ewout , Groothuis Jan T. , van Engelen Baziel G.M. , Nijveldt Robin , Erasmus Corrie E. , Udink ten Cate Floris E.A. , Voermans Nicol C.
Published: August 2024

Background:

LAMA2-related muscular dystrophy (LAMA2-MD) and SELENON-related myopathy (SELENON-RM) are two rare neuromuscular diseases characterized by proximal and axial muscle weakness, scoliosis, spinal rigidity, low bone quality and respiratory impairment. Cardiac involvement has previously been described in retrospective studies and case reports, but large case series and prospective studies in unselected cohorts are lacking.

Objective:

The objective of this study is to conduct prevalence estimations, perform cardiac phenotyping, and provide recommendations for clinical care.

Methods:

In this case series including two time points, we conducted comprehensive assessments with electrocardiography (ECG) and transthoracic echocardiography (TTE). ECGs were systematically assessed for a large subset of variables. TTE included left and right ventricular ejection fraction (LVEF/RVEF) and left ventricular global longitudinal strain (GLS), the latter being a more early and sensitive marker of left ventricular dysfunction.

Results:

21 LAMA2-MD (M = 5; 20±14 years) and 10 SELENON-RM patients (M = 7; 18±12 years) were included. In most patients, QRS fragmentation and Q waves, markers of heterogeneous ventricular activation, were present both at baseline and at follow-up. GLS was abnormal (age specific in children, > –18% in adults) in 33% of LAMA2-MD and 43% of SELENON-RM patients at baseline. Reduced LVEF (<52% in males, <54% in females and <55% in pediatric population) was observed in three LAMA2-MD patients at baseline and in none of the SELENON-RM patients. GLS and LVEF did not change between baseline and follow-up. RVEF was normal in all patients.

Conclusion:

ECG abnormalities and abnormal GLS are prevalent in LAMA2-MD and SELENON-RM, yet abnormal LVEF was only seen in LAMA2-MD patients. One LAMA2-MD patient had a clinically relevant deterioration in LVEF during 1.5-year follow-up. We advise routine screening of all patients with LAMA2-MD or SELENON-RM with ECG and echocardiography at diagnosis, minimally every two years from second decade of life and if new cardiac signs arise.
New skills in symbolic data analysis for official statistics
Authors: Verde Rosanna , Batagelj Vladimir , Brito Paula , Silva A. Pedro Duarte , Korenjak-Černe Simona , Dobša Jasminka , Diday Edwin
Published: August 2024

The paper draws attention to the use of Symbolic Data Analysis (SDA) in the field of Official Statistics. It is composed of three sections presenting three pilot techniques in the field of SDA. The three contributions range from a technique based on the notion of exactly unified summaries for the creation of symbolic objects, a model-based approach for interval data as an innovative parametric strategy in this context, and measures of similarity defined between a class and a collection of classes based on the frequency of the categories which characterize them.

The paper shows the effectiveness of the proposed approaches as prototypes of numerous techniques developed within the SDA framework and opens to possible further developments.
Evaluating the therapeutic effects of NiaoDuQing particles on chronic kidney disease based on real world study
Authors: Sun Rui , Hao Jianfeng , Li Qian , Xie Weinan , Hu Xiaoyan , Chen Zhenzhen , Liu Zhi , Yuan Ling
Published: August 2024

BACKGROUND:

NiaoDuQing Particle is the first Chinese herbal medicine approved by the China Food and Drug Administration for the treatment of chronic kidney disease. It has been used in clinical practice in China for over twenty years. However, there is limited literature reporting on the long-term therapeutic effects of NiaoDuQing Particles on chronic kidney disease patients.

OBJECTIVE:

This research aimed to comprehensively assess the therapeutic effect of NiaoDuQing Particles (NDQP) on chronic kidney disease patients based on clinical data analysis.

METHODS:

This study was carried out on a total of 148 participants diagnosed with different types of chronic kidney disease. Demographics information, chronic kidney disease classification and chronic kidney disease diganostic indicators were collected and analyzed before and after NiaoDuQing Particles treatment for 3, 6, 9, 12 and 18 months respectively.

RESULTS:

In all 148 patients, mean eGFR value was increased after NiaoDuQing Particles treatment for up to 18 months, and was statistically significant at month 3, 6, 9, 12 and 18 ([Formula: see text] 0.05). Mean uric acid value was decreased after NiaoDuQing Particles treatment for up to 18 months, and was statistically significant at month 3, 6, 9, 12 and 18 ([Formula: see text] 0.05). Mean urea nitrogen value was decreased after NiaoDuQing Particles treatment for up to 18 months and was statistically significant at month 3, 6, 9, 12 and 18 ([Formula: see text] 0.05). While mean creatinine value was decreased after NiaoDuQing Particles treatment for up to 18 months and was statistically significant at month 6 ([Formula: see text] 0.05).

CONCLUSIONS:

NiaoDuQing Particles could maintain the stable state of chronic kidney disease patients for up to 18 months especially in improving diagnostic indicators like eGFR, uric acid and urea nitrogen.