bluuebunny/crossref_metadata_2025 huggingface dataset:
Imaging of the medial collateral ligament of the knee: a systematic review
Authors: Meyer P. , Reiter A. , Akoto R. , Steadman J. , Pagenstert G. , Frosch K. H. , Krause M.
Published: October 2021

Introduction

The primary aim of this investigation was to systematically review relevant literature of various imaging modalities (magnetic resonance imaging (MRI), stress radiography and ultrasonography) in the assessment of patients with a medial collateral ligament (MCL) injury.

Materials and methods

A systematic literature review of articles indexed in PubMed and Cochrane library was performed. Original research reporting data associated with medial gapping, surgical, and clinical findings associated with MCL injuries were considered for inclusion. The methodological quality of each inclusion was also assessed using a verified tool.

Results

Twenty-three imaging studies (magnetic resonance imaging (MRI) n = 14; ultrasonography n = 6; radiography n = 3) were ultimately included into the review. A total of 808 injured, and 294 control, knees were assessed. Interobserver reliabilities were reported in radiographic and ultrasonographic investigations with almost perfect agreement. MRI studies demonstrated agreement ranging between substantial to almost perfect. Intraobserver reliability was only reported in radiographic studies pertinent to medial gapping and was found to be almost perfect. Correlation of MRI with clinical findings was moderate to strong (65–92%). Additionally, MRI imaging was more sensitive in the detection of MCL lesions when compared to clinical examination. However, when compared to surgical findings, MRI underestimated the grade of instability in up to 21% of cases. Furthermore, MRI showed relatively inferior performance in the identification of the exact MCL-lesion location when compared to surgical findings. Interestingly, preoperative clinical examination was slightly inferior to stress radiography in the detection of MCL lesions. However, clinical testing under general anaesthesia performed similar to stress radiography. The methodological quality analysis showed a low risk of bias regarding patient selection and index testing in each imaging modality.

Conclusion

MRI can reliably diagnose an MCL lesion but demonstrates limitations in its ability to predict the specific lesion location or grade of MCL instability. Ultrasonography is a widely available, radiation free modality, but is rarely used in clinical practice for detecting MCL lesions and clinical or surgical correlates are scarce. Stress radiography findings correlate with surgical findings but clinical correlations are missing in the literature.

Level of evidence

IV.
Area modulates the effect of elevation but not of land use or canopy on tropical plant species richness
Authors: Hemp Andreas , Del Fabbro Corina , Fischer Markus
Published: October 2021

One of the few general patterns in ecology is the increase of species richness with area. However, factors driving species-area relationship (SAR) are under debate, and the role of human-induced changes has been overlooked so far. Furthermore, SAR studies in tropical regions, in particular in multilayered rain forests are scarce. On the other side, studies of global change-induced impacts on biodiversity have become increasingly important, particular in the tropics, where these impacts are especially pronounced. Here, we investigated if area modulates the effect of land use, elevation and canopy on plant species richness. For the first time we studied SAR in multilayered tropical forests considering all functional groups. We selected 13 natural and disturbed habitats on Kilimanjaro in Tanzania, distributed over an elevational range of 3700 m. In each habitat type, we set up three to six modified Whittaker plots. We recorded all plant species in 64 plots and 640 subplots and described SAR using the power function. Area consistently modulated effects of elevation on plant species richness, partly effects of land use but not effects of plant canopy. Thus, area needs to be taken into account when studying elevational plant species richness patterns. In contrast to temperate regions open and forest habitats did not differ in SAR, probably due to a distinct vertical vegetation zonation in tropical forests. Therefore, it is important to consider all vegetation layers including epiphytes when studying SAR in highly structured tropical regions.
Efficacy and safety of mitoxantrone hydrochloride liposome injection in Chinese patients with advanced breast cancer: a randomized, open-label, active-controlled, single-center, phase II clinical trial
Authors: Wang Leiping , Cao Jun , Li Chunlei , Wang Xiaodong , Zhao Yannan , Li Ting , Du Yiqun , Tao Zhonghua , Peng Wenxia , Wang Biyun , Zhang Jian , Zhang Sheng , Wang Zhonghua , Hu Xichun
Published: October 2021

Purpose. This trial aimed to evaluate the efficacy and safety of mitoxantrone hydrochloride liposome injection (Lipo-MIT) in advanced breast cancer (ABC). Methods. In this randomized, open-label, active-controlled, single-center, phase II clinical trial, eligible patients were randomized in a ratio of 1:1 to receive Lipo-MIT or mitoxantrone hydrochloride injection (MIT) intravenously. The primary endpoint was objective response rate (ORR). The secondary endpoints were disease control rate (DCR), progression-free survival (PFS), and safety outcomes. Results. Sixty patients were randomized to receive Lipo-MIT or MIT. The ORR was 13.3% (95% confidence interval (CI): 3.8–30.7%) for Lipo-MIT and 6.7% (95% CI: 0.8–22.1%) for MIT. The DCR was 50% (95% CI: 31.3–68.7%) with Lipo-MIT vs. 30% (95% CI: 14.7–49.4%) with MIT. The median PFS was 1.92 months (95% CI: 1.75–3.61) for Lipo-MIT and 1.85 months (95% CI: 1.75–2.02) for MIT. The most common toxicity was myelosuppression. Lipo-MIT resulted in an incidence of 86.7% of leukopenia and 80.0% of neutropenia, which was marginally superior to MIT (96.7% and 96.7%, respectively). Lipo-MIT showed a lower incidence of cardiovascular events (13.3% vs. 20.0%) and increased cardiac troponin T (3.3% vs. 36.7%); but higher incidence of anemia (76.7% vs. 46.7%), skin hyperpigmentation (66.7% vs. 3.3%), and fever (23.3% vs. 10.0%) than MIT. Conclusions The clinical benefit parameters of Lipo-MIT and MIT were comparable. Lipo-MIT provided a different toxicity profile, which might be associated with the altered distribution of the drug. Additional study is needed to elucidate the potential benefit of Lipo-MIT in ABC. Clinical trial registration. This study is registered with ClinicalTrials.gov (No. NCT02596373) on Nov 4, 2015.
Do students need more information to leave the beaten paths? The impact of a counseling intervention on high school students’ choice of major
Authors: Piepenburg Joachim G. , Fervers Lukas
Published: October 2021

Despite an almost endless list of possible study programs and occupational opportunities, high school students frequently focus on pursuing a small number of well-known study programs. Students also often follow gender-typical paths and restrict their attention to study programs in which the majority of students consists of same-gendered people. This choice pattern has far-reaching consequences, including persistent gender segregation and an undersupply of graduates in emerging sectors of the industry. Building on rational choice and social psychological theory, we argue that this pattern partly occurs due to information deficits that may be altered by counseling interventions. To assess this claim empirically, we evaluated the impact of a counseling intervention on the intended choice of major among high school students in Germany by means of a randomized controlled trial (RCT). We estimate the effect by instrumental variable estimation to account for two-sided non-compliance. Our results show that the intervention has increased the likelihood that participants will consider less well-known or gender-atypical study programs, particularly for high school students with lower starting levels of information. Supplementary analyses confirm that a positive impact on information seems to be one of the relevant causal mechanisms. These results suggest that counseling services have the potential to guide high school students to less gender-typical and well-known majors, possibly reducing gender segregation and smoothing labor market transitions after graduation.
“Maybe this is Speculative Now” Negotiating and Valuing Interpretations in Qualitative Research
Authors: Berli Oliver
Published: October 2021

Interpretation groups, which meet on a regular basis for jointly analysing qualitative data, are well-established in sociology and related disciplines. There are currently at least 71 interpretation groups in German-speaking countries, and there are more if one includes project teams, which meet on a regular basis for data sessions. Yet, there is relatively little knowledge based on empirical research about these groups and their practices. Inspired by studies on social sciences and humanities (SSH), this article examines how “good” interpretations are jointly created in these groups. Prior studies underlined that social scientific methods are productive, i.e., performative. Following this lead, my study turns data analysis in qualitative research into an object of inquiry by investigating how interpretation groups work on textual data. More specifically, this article discusses how these groups negotiate different interpretative options and at the same time evaluate the quality of their results as well as the interpretation process as a whole. In this regard, the approach presented in this article also contributes to the growing literature on valuation and evaluation in science by focusing on communicative devices for valuing and evaluating interpretations.
“Wild Years”: Rock Music, Problem Behaviors and Mental Well-being in Adolescence and Young Adulthood
Authors: Bogt Tom T. , Hale William W. , Becht Andrik
Published: October 2021

Adolescent preferences for non-mainstream types of rock music can be markers of adolescent problem behaviors, but no study has ever investigated whether this relationship continues into adulthood. In a six-wave study, 900 Dutch adolescents were followed from ages 12 to 21 (MageT1 12.4, 51.1% girls), while reporting on depressive symptoms, mental well-being, aggression and drug use. A latent class growth analysis on their preferences for specific types of rock music revealed four fan groups. When these fan groups were compared to one another, in adolescence, theall-out rock fansdisplayed the highest peak in depressive symptoms and the lowest dip in well-being and therock/metal fansreported the most aggression. And for both these groups, drug use increased at the onset of adulthood.Pop fansdisplayed a profile characterized by low depressive symptoms and aggression, and high in mental well-being. Finally, thepopular rock fansheld an in-between position between pop fans, on one side, and the all-out rock fans and rock/metal fans, on the other side. Thus, music preferences can be markers of problems, not only in adolescence but also in young adulthood. Still, music can enhance mood, helps to cope with problems, and peers in fan groups can provide support. This research focuses on the relationship between music and problem behaviors, specifically among members of the all-out rock fans and rock/metal fans, but many of these young people might have had more personal problems if they had not had their music and their fan-group peers.
Enactive Ethics: Difference Becoming Participation
Authors: Di Paolo Ezequiel A. , De Jaegher Hanne
Published: October 2021

Enactive cognitive science combines questions in epistemology, ontology, and ethics by conceiving of bodies as open-ended and mutually transforming through activity. While enaction is not a theory of ethics, it can contribute to its foundations. We present a schematization of enactive ideas that underlie traditional distinctions between Being, Knowing, and Doing. Ethics in this scheme begins in the relation between knowing and becoming. Critical of dichotomous thinking, we approach the questions of alterity and ethical reality. Alterity is relevant to the enactive approach, but not in the radical sense of transcendental arguments. We propose difference, instead, as a more generative concept. Following Simondon, we see norms and values manifest in webs of past and future acts together with their potentialities for becoming. We propose a transindividual concept of moral attunement that includes ethical know-how and consciousness raising. Through generative difference and attunement to configurations of becoming, enaction underpins an ethics of participation linking virtue ethics and ethics of care.
Quality of Life After Bariatric Surgery—a Systematic Review with Bayesian Network Meta-analysis
Authors: Małczak Piotr , Mizera Magdalena , Lee Yung , Pisarska-Adamczyk Magdalena , Wysocki Michał , Bała Małgorzata M. , Witowski Jan , Rubinkiewicz Mateusz , Dudek Alicja , Stefura Tomasz , Torbicz Grzegorz , Tylec Piotr , Gajewska Natalia , Vongsurbchart Tanawat , Su Michael , Major Piotr , Pędziwiatr Michał
Published: October 2021

Objective

Comprehensive analysis and comparison of HRQoL following different bariatric interventions through systematic review with network meta-analysis.

Background

Different types of bariatric surgeries have been developed throughout the years. Apart from weight loss and comorbidities remission, improvement of health-related quality of life (HRQoL) is an important outcome of metabolic surgery.

Methods

MEDLINE, EMBASE, and Scopus databases have been searched up to April 2020. Inclusion criteria to the analysis were (1) study with at least 2 arms comparing bariatric surgeries; (2) reporting of HRQoL with a validated tool; (3) follow-up period of 1, 2, 3, or 5 years. Network meta-analysis was conducted using Bayesian statistics. The primary outcome was HRQoL.

Results

Forty-seven studies were included in the analysis involving 26,629 patients and 11 different surgeries such as sleeve gastrectomy (LSG), gastric bypass (LRYGB), one anastomosis gastric bypass (OAGB), and other. At 1 year, there was significant difference in HRQoL in favor of LSG, LRYGB, and OAG compared with lifestyle intervention (SMD: 0.44; 95% CrI 0.2 to 0.68 for LSG, SMD: 0.56; 95% CrI 0.31 to 0.8 for LRYGB; and SMD: 0.43; 95% CrI 0.06 to 0.8 for OAGB). At 5 years, LSG, LRYGB, and OAGB showed better HRQoL compared to control (SMD: 0.92; 95% CrI 0.58 to 1.26, SMD: 1.27; 95% CrI 0.94 to 1.61, and SMD: 1.01; 95% CrI 0.63 to 1.4, respectively).

Conclusions

LSG and LRYGB may lead to better HRQoL across most follow-up time points. Long-term analysis shows that bariatric intervention results in better HRQoL than non-surgical interventions.

Graphical abstract
Nature of CoCrFeMnNi/Fe and CoCrFeMnNi/Al Solid/Solid Interface
Authors: Li Zhongtao , Zhang Weidong , Wu Zhenggang
Published: October 2021

To shed light into the application potential of high-entropy alloys as “interlayer” materials for Al-steel solid-state joining, we investigated the nature of the CoCrFeMnNi/Fe and CoCrFeMnNi/Al solid/solid interfaces, focusing on the bonding behavior and phase components. Good metallurgical bonding without the formation of hard and brittle IMC can be achieved for CoCrFeMnNi/Fe solid/solid interface. In contrast to the formation of Al5Fe2 phase at the Fe/Al interface, Al13Fe4-type IMC, in which the Fe site is co-occupied equally by Co, Cr, Fe, Mn and Ni, dominates the CoCrFeMnNi/Al interface. Although the formation of IMC at the CoCrFeMnNi/Al interface is not avoidable, the thickness and hardness of the Al13(CoCrFeMnNi)4 phase formed at the CoCrFeMnNi/Al interface are significantly lower than the Al5Fe2 phase formed at the Fe/Al interface. The activation energies for the interdiffusion of Fe/Al and CoCrFeMnNi/Al static diffusion couple are 341.6 kJ/mol and 329.5 kJ/mol, respectively. Despite this similarity, under identical static annealing condition, the interdiffusion coefficient of the CoCrFeMnNi/Al diffusion couple is significantly lower than that of the Fe/Al diffusion couple. This is thus mainly a result of the reduced atomic mobility/diffusivity caused by the compositional complexity in CoCrFeMnNi high-entropy alloy.
Resolved CFD-DEM simulation of blood flow with a reduced-order RBC model
Authors: Balachandran Nair Achuth Nair , Pirker Stefan , Saeedipour Mahdi
Published: October 2021

Mathematical modeling of the blood flow with a resolved description of biological cells mechanics such as red blood cell (RBC) has been a challenge in the past decades as it involves physical complexities and demands high computational costs. In the present study, we propose an approach for efficient simulation of blood flow with several suspended RBCs. In this approach, we employ our previously proposed reduced-order model for deformable particles (Nair et al. in Comput Part Mech 7:593–601, 2020) to mimic the mechanical behavior of an individual RBC as a cluster of overlapping spheres interconnected by flexible mathematical bonds. This discrete element method-based model is then coupled with a fluid flow solver using the immersed boundary method with continuous forcing in the context of computational fluid dynamics-discrete element method (CFD-DEM) coupling. The present computational method is tested with a couple of validation cases in which the single RBC dynamics, as well as the blood flow with several RBCs, were tested in comparison with existing literature date. First, the RBC deformation index in shear flow at different shear rates is studied with a good accuracy. Then, the blood flow in micro-tubes of different diameters and hematocrits was simulated. The key characteristics of blood flow such as cell-free layer (CFL) thickness, Fahraeus effect and the relative apparent viscosity are used as the validation metrics. The proposed approach can predict the formation of the migration of RBC toward the tube center-line and the CFL thickness in good agreement with previous measurement and simulations. Furthermore, the model is employed to study the CFL enhancement for plasma separation based on channel constriction. The simulation results compute the CFL thickness downstream of the channel constriction in good agreement with the experiments in a wide range of flow rates and constriction lengths. The original contribution of this study lies in proposing an efficient resolved CFD-DEM simulation method for blood flows with many RBCs which can be employed for numerical investigation of bio-microfluidic applications.
Mindfulness Meditation Influences Implicit but Not Explicit Coding of Temporal Simultaneity
Authors: Elliott Mark A. , Zalewska Monika , Wittmann Marc
Published: October 2021

In the meditative state time appears to slow down and in the present moment it expands. However, to date, there is no investigation of the effect of meditative state on the structure of the “psychological moment”; this is the measurable, minimal duration of the moment “now.” In this study, we examined the effect on the psychological moment of a mindfulness intervention against an intervention in which participants listened to classical music. The psychological moment was measured using a simultaneity-detection paradigm from which the threshold between reports that two targets changed luminance simultaneously or with an asynchrony is normally taken as the duration of the moment. In line with previous research, this paradigm allowed for examination of the effects of the subthreshold synchronized, or asynchronized target onsets, which occurred prior to the luminance change of the targets. While there was no overall difference in the psychological moment pre- and post-, and as a function of the type of intervention, a bias against reporting simultaneity following presentation of a subthreshold asynchrony, which lowered thresholds and so shortened the psychological moment, was reduced after the mindfulness intervention. From this we conclude that even brief mindfulness meditation can encourage a more focalized attentional response, which can in turn be used to normalize psychological time.
Interfacial X-Ray Scattering From Small Surfaces: Adapting Mineral-Fluid Structure Methods for Microcrystalline Materials
Authors: Stubbs Joanne E. , Wanhala Anna K. , Eng Peter J.
Published: October 2021

Crystal truncation rod (CTR) X-ray diffraction is an invaluable tool for measuring mineral surface and adsorbate structures, and has been applied to several environmentally and geochemically important systems. Traditionally, the method has been restricted to single crystals with lateral dimensions >3 mm. Minerals that meet this size criterion represent a minute fraction of those that are relevant to interfacial geochemistry questions, however. Crystal screening, data collection, and CTR measurement methods have been developed for crystals of <0.3 mm in lateral size using the manganese oxide mineral chalcophanite (ZnMn3O7·3H2O) as a case study. This work demonstrates the feasibility of applying the CTR technique to previously inaccessible surfaces, opening up a large suite of candidate substrates for future study.
Distance to news: how social media information affects bribe-giving in India
Authors: Goto Jun , Kurosaki Takashi , Mori Yuko
Published: October 2021

While recent empirical evidence reveals some effective interventions in preventing corruption among bureaucrats and politicians, there has been little discussion on how to prevent the bribe-giving behavior of ordinary citizens. This paper investigates the role of social media information in influencing the supply of bribes by citizens instead of the demand side. We, therefore, developed and published an original news application in India and implemented a 3-month experiment. In this application, we randomly circulate live news related to corruption to users and incorporate a lab experiment into the app system to elicit users’ bribery behavior every week. We find that corruption news involving politicians within a close geographical proximity lowers users’ moral costs against the anti-social bribery act, leading to an increase in the amount of bribes. However, news of accused citizens and officials within the geographic proximity increases their moral cost against bribes and decreases the amount. This suggests that individually tailored local information on corruption may be an effective tool to reduce citizens’ supply of bribes.
Kurdish Politics in Iran
Authors: Hassaniyan Allan
Published: October 2021

Reflecting on seven decades of the Iranian Kurdish movement, this book offers a comprehensive and critical analysis of the politicisation of national sentiments within Iran, and the connections the movement made and developed with Kurdish groups in Iraq. Looking at Kurdish-state relations through events taking place across remote, rural and urban areas in Kurdistan, Allan Hassaniyan analyses nationalist as well as non-nationalist aspects of Kurdish politics and history, reading the evolution of Kurdish nationalism through analysing crossborder Kurdish interaction. Paying particular attention to movement mobilisation and different aspects of the collective actions and insurgency deployed by actors, civil society organisations and the political parties of Iranian Kurds during different phases of the movement, Hassaniyan demonstrates how the ethnonationalist movement of the Iranian Kurds was a product of a discriminatory policy pursued by changing Iranian regimes toward non-Persian and non-Shiite communities in the country, particularly in the second half of the twentieth century.
Saving the Freedom of Information Act
Authors: Kwoka Margaret B.
Published: October 2021

Enacted in 1966, The Freedom of Information Act (or FOIA) was designed to promote oversight of governmental activities, under the notion that most users would be journalists. Today, however, FOIA is largely used for purposes other than fostering democratic accountability. Instead, most requesters are either individuals seeking their own files, businesses using FOIA as part of commercial enterprises, or others with idiosyncratic purposes like political opposition research. In this sweeping, empirical study, Margaret Kwoka documents how agencies have responded to the large volume of non-oversight requesters by creating new processes, systems, and specialists, which in turn has had a deleterious impact on journalists and the media. To address this problem, Kwoka proposes a series of structural solutions aimed at shrinking FOIA to re-center its oversight purposes.
IoT innovation clusters in Europe and the case for public policy
Authors: Remotti Luca Alessandro
Published: October 2021

The Internet of Things (IoT) is currently developing fast and its potential as driver of innovative solutions is increasing, pushed by technologies, networks, communication, and computing power, and has the potential to drive the development of technological ecosystems, such as innovation clusters. Innovation clusters are agglomeration of enterprises and research organizations, which cooperate, interact and compete, generating innovation and driving the growth of ecosystems. The narrative around innovation clusters has been developing since many years and policy-makers seek to use such clusters as a policy instrument to support the growth of technology on the one hand and regional and sectoral development on the other hand. This policy paper expands an empirical study on IoT innovation clusters in Europe and places it within the current debate around clusters and innovation clusters to provide evidence-based advice to policy-makers on what may and may not work as public policy measures. The paper highlights the findings of the interaction with several hundred European IoT innovation clusters and points out their points of view on their own creation factors, operational characteristics, and success stories, as well as their expectations in respect to policy interventions for IoT and for clusters. Suggestions for IoT policy-making are provided. The paper has also undertaken an extensive review of up-to date research on innovation cluster creation and performance, thoroughly analyzing the real possibility to define causal relationships between clusters, productivity and economic growth, and business performance, and providing suggestions for policy-makers on the approach to cluster policy.
Digital Strategies to Improve Food Assistance in Disasters: A Scoping Review
Authors: Martin Nina M. , Sundermeir Samantha M. , Barnett Daniel J. , van Dongen Ellen J. I. , Rosman Lori , Rosenblum Andrew J. , Gittelsohn Joel
Published: October 2021

Objective:

Modern digital strategies, including Internet of Things, machine learning, and mobile applications, have revolutionized situational awareness during disaster management. Despite their importance, no review of digital strategies to support emergency food security efforts has been conducted. This scoping review fills that gap.

Methods:

Keywords were defined within the concepts of food assistance, digital technology, and disasters. After the database searches, PRISMA guidelines were followed to perform a partnered, 2-round scoping literature review.

Results:

The search identified 3201 articles, and 26 articles met criteria and were included in the analysis. The data types used to describe the tools were text/opinion (42.3%), qualitative (23.1%), system architecture (19.2%), quantitative and qualitative (11.5 %), and quantitative (3.8%). The tools’ main functions were Resource Allocation (41.7%), Data Collection and Management (33%), Interagency Communications (15.4 %), Beneficiary Communications (11.5%), and Fundraising (7.7%). The platforms used to achieve these goals were Mobile Application (36%), Internet of Things (20%), Website (20%), and Mobile Survey (8%); 92% covered the disaster response phase.

Conclusions:

Digital tools for planning, situational awareness, client choice, and recovery are needed to support emergency food assistance, but there is a lack of these tools and research on their effectiveness across all disaster phases.
A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study
Authors: Nakamura Yasuyuki , Narita Akira , Sutoh Yoichi , Imaeda Nahomi , Goto Chiho , Matsui Kenji , Takashima Naoyuki , Kadota Aya , Miura Katsuyuki , Nakatochi Masahiro , Tamura Takashi , Hishida Asahi , Nakashima Ryoko , Ikezaki Hiroaki , Hara Megumi , Nishida Yuichiro , Takezaki Toshiro , Ibusuki Rie , Oze Isao , Ito Hidemi , Kuriyama Nagato , Ozaki Etsuko , Mikami Haruo , Kusakabe Miho , Nakagawa-Senda Hiroko , Suzuki Sadao , Katsuura-Kamano Sakurako , Arisawa Kokichi , Kuriki Kiyonori , Momozawa Yukihide , Kubo Michiaki , Takeuchi Kenji , Kita Yoshikuni , Wakai Kenji ,   for the J-MICC Research Group
Published: October 2021

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption. Although meat is a major source of protein and fat in the diet, whether genetic factors that influence meat-eating habits in healthy populations are unknown. This study aimed to conduct a GWAS to find genetic variations that affect meat consumption in a Japanese population. We analysed GWAS data using 14 076 participants from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. We used a semi-quantitative food frequency questionnaire to estimate food intake that was validated previously. Association of the imputed variants with total meat consumption per 1000 kcal energy was performed by linear regression analysis with adjustments for age, sex, and principal component analysis components 1–10. We found that no genetic variant, including rs671, was associated with meat consumption. The previously reported single nucleotide polymorphisms that were associated with meat consumption in samples of European ancestry could not be replicated in our J-MICC data. In conclusion, significant genetic factors that affect meat consumption were not observed in a Japanese population.
Holocene relative sea-level data for the East Frisian barrier coast, NW Germany, southern North Sea
Authors: Bungenstock Friederike , Freund Holger , Bartholomä Alexander
Published: October 2021

Collecting sea-level data from restricted coastal areas is essential for understanding local effects on relative sea level. Here, a revised relative mean sea-level curve for the area of the East Frisian island Langeoog, northwestern Germany, for the time period from 7200 cal BP until Recent is presented. The revision is based on the reinterpretation of previously published and unpublished data following the HOLSEA standardisation of data handling. Altogether 68 sea-level data taken from 32 cores and outcrops from Langeoog, its back-barrier and the adjacent mainland, which have been collected since the 1950s for mapping and landscape reconstruction purposes, are presented. The age constraints, derived from radiocarbon ages of basal peat, intercalated peat and molluscs and optical dating of tidal deposits, were evaluated in terms of the HOLSEA sea-level protocol and their stratigraphic context. For 7200 cal BP until modern times, 30 sea-level index points with different uncertainty ranges were defined. Additionally, a factor of decompaction was estimated for the remaining basal peat samples as well as for the underlying sediments of intercalated peat samples.

The comparison of the Langeoog relative sea-level curve with the relative sea-level curve from the western Netherlands shows that the Langeoog curve lies up to 0.80 m lower than the Dutch curve and diverges for the time before 6000 cal BP. Though the offset coincides with the overall predicted trend of glacial-isostatic adjustment, it is less than predicted.

Our study provides a useful assessment of legacy data and contributes to an improved sea-level index dataset for the southern North Sea coast.
Global well-posedness and decay estimates for three-dimensional compressible Navier–Stokes–Allen–Cahn systems
Authors: Zhao Xiaopeng
Published: October 2021

We study the small data global well-posedness and time-decay rates of solutions to the Cauchy problem for three-dimensional compressible Navier–Stokes–Allen–Cahn equations via a refined pure energy method. In particular, the optimal decay rates of the higher-order spatial derivatives of the solution are obtained, the $\dot {H}^{-s}$($0\leq s<\frac {3}{2}$) negative Sobolev norms is shown to be preserved along time evolution and enhance the decay rates.
Decay properties for the incompressible Navier-Stokes flows in a half space
Authors: Han Pigong
Published: October 2021

In this article, we give a comprehensive characterization of$L^1$-summability for the Navier-Stokes flows in the half space, which is a long-standing problem. The main difficulties are that$L^q-L^r$estimates for the Stokes flow don't work in this end-point case:$q=r=1$; the projection operator$P: L^1\longrightarrow L^1_\sigma$is not bounded any more; useful information on the pressure function is missing, which arises in the net force exerted by the fluid on the noncompact boundary. In order to achieve our aims, by making full use of the special structure of the half space, we decompose the pressure function into two parts. Then the knotty problem of handling the pressure term can be transformed into establishing a crucial and new weighted$L^1$-estimate, which plays a fundamental role. In addition, we overcome the unboundedness of the projection$P$by solving an elliptic problem with homogeneous Neumann boundary condition.
Law’s Elasticity An Inquiry into the Relation of Law and Power in Finance
Authors: Pistor Katharina
Published: October 2021

Law is a powerful commitment device. By entering into a binding contract, a contracting party can invoke the coercive law enforcement powers of states to compel another party to perform. Many, if not most, contracts are carried out without ever invoking these coercive powers; they operate in the shadow of the law. Less attention has been paid to the flip side of law’s shadow: the possibility of relaxing or suspending the full force of the law, or making law elastic. While this may seem anathema to the “rule of law”, it is not an infrequent occurrence, especially in times of crisis. The elasticity of law should be distinguished from the incompleteness of law, that is, the inherent limitation lawmakers face in trying to anticipate all future contingencies. In this paper I will offer two tales of the American Insurance Group (AIG) to illustrate the elasticity of contracts as well as of law.
Denis Papin's digester and its eighteenth-century European circulation
Authors: Storni Marco
Published: October 2021

The digester, invented by Denis Papin in the 1680s, was a rudimentary pressure cooker used to soften hard bodies by boiling them at high pressure. In this paper, I propose a reassessment of Papin's work on the digester, arguing that his research was located at the intersection of the chemical laboratory and cooking practice. I then examine cases from the eighteenth-century European circulation of the instrument in Sweden, Italy and the Netherlands in order to showcase the different practices in which the digester was embedded, including chemical research, philanthropic projects to feed the destitute, and proposals for the improvement of home cooking. The digester's history represents a key episode for demonstrating the intertwined nature of natural-philosophical research and the practice of economy or ‘thrift’. All users of the digester engaged in a rationalization of its functions through quantification, not only to fulfil a concern for precision but also to display the device's potential to reform practical daily life. The digester could save time and fuel, reduce material waste, make cooking easier and foster collective meal preparation for the needy.
Remembering St Brictius: Conspiracy, Violence and Liturgical Time in the Danish Massacre of 1002
Authors: SAVILL BENJAMIN
Published: October 2021

This article builds upon recent scholarship on the role of church ‘reform’ and the cult of saints in English royal politics around the turn of the second millennium, arguing that the infamous ‘St Brice's Day massacre’ of 13 November 1002 may have been planned for that date in part because of the associations of the cult of Brice/Brictius. After outlining this hypothesis, the article explores the broader implications of the emergence of a universal martyrological calendar for historical writing and political action, and for the exercise and communication of violence in particular.
Private Benefits, Public Vices: Railways and Logrolling in the Nineteenth-Century British Parliament
Authors: Esteves Rui , Geisler Mesevage Gabriel
Published: October 2021

Vote trading among lawmakers (logrolling) can enable political rent-seeking but is difficult to identify. To achieve identification, we explore the rules governing voting for railway projects in the U.K. Parliament during the Railway Mania of the 1840s. Parliamentary rules barred MPs from voting directly for their interests. Even so, they could trade votes to ensure their interests prevailed. We find that logrolling was significant, accounting for nearly one-quarter of the railway bills approved. We also quantify a negative externality to society from logrolling ranging from 1/3 to 1 percent of contemporary GDP.
RICHARD T. ELY, THE GERMAN HISTORICAL SCHOOL OF ECONOMICS, AND THE “SOCIO-TELEOLOGICAL” ASPIRATION OF THE NEW DEAL PLANNERS
Authors: Miller Tiffany Jones
Published: October 2021

Richard T. Ely was one of the most important architects of the administrative welfare state in the United States. His astonishingly influential career was the product of a fundamental re-thinking of the origin and nature of the state. Repudiating the social compact theory of the American founding in favor of a self-consciously “new,” “German,” and frankly “social” conception of the state ordered toward the realization of a collective vision of human perfection, Ely conceived the task of social reform as extending social control over the hereditary and environmental determinants of human character. In the early 1930s, Ely’s vision of social reform would inspire some of his boldest students, especially M. L. Wilson, to formulate a sweeping vision of social planning that would not only inform his little known and rather coyly named Division of Subsistence Homesteads, but also his efforts at the National Resources Board (NRB)—the nation’s first ever agency for comprehensive national planning.
SNAP EXCLUSIONS AND THE ROLE OF CITIZEN PARTICIPATION IN POLICY-MAKING
Authors: Hutler Brian , Barnhill Anne
Published: October 2021

This essay uses a specific example—proposals to exclude sugary drinks from the Supplemental Nutrition Assistance Program (SNAP)—to explore some features of the contemporary U.S. administrative state. Dating back to the Wilsonian origins of the U.S. administrative state there has been uncertainty about whether we can and should separate politics and administration. On the traditional view, the agencies are to be kept separate from politics—technocratic and value-neutral—although they are indirectly accountable to the president and Congress. The SNAP exclusions example shows, however, that agencies often must make complex and controversial decisions on their own, decisions that go beyond value-neutral technocratic administration. When authorizing legislation has multiple goals, as we’ll argue is the case in the SNAP example, an agency will have to choose between conflicting statutory mandates. Moreover, as the SNAP example shows, agencies often face complex normative questions of ethics and justice that go beyond the question of how to balance competing aims. The appropriate response to the SNAP exclusions example is not to keep politics out of administrative decision-making, but to develop procedures that allow ethical and political questions to be addressed in agency policy-making, consistent with overarching commitments to fairness and democracy.
Cardiac features in a patient with erythrokeratodermia cardiomyopathy syndrome
Authors: Ichikawa Yasuhiro , Shibuya Yuma , Tanaka Mio , Kurosawa Kenji , Ueda Hideaki
Published: October 2021

Patients with erythrokeratodermia cardiomyopathy syndrome exhibit congenital, generalised erythrokeratoderma and dilated cardiomyopathy during early childhood. We report a case of erythrokeratodermia cardiomyopathy syndrome in a 15-year-old male patient and focus this report on cardiac features that were present.
Institutions and Arguments: Simulating the US Policy-Making Process
Authors: Britt Lucy , Williams Ryan J.
Published: October 2021

In US government courses, simulations have been shown to increase students’ engagement and knowledge retention. We present an original simulation that focuses on both the interactions between political institutions that contribute to policy making and the normative ideas underlying politics. By exploring a civil rights or liberties policy area, students learn about the importance of both political institutions and foundational political ideas such as liberty and equality. Students role-play members of Congress, lobbyists for a pro- or anti-natural gas pipeline group, and Supreme Court justices. Although the goal of simulations in many US government courses is to teach students about the ways that institutions shape policy, this is the first (to our knowledge) that also integrates normative reflection on the ideas behind political arguments. Assessment indicates that the simulation was effective in increasing students’ knowledge of and/or interest in American political institutions and eminent domain.
Paṇḍit Seu to Mānaku: a pictorial Rāmāyaṇa with text
Authors: Brockington John
Published: October 2021

This article examines the linked sets of paintings commonly known as the “small Guler” Rāmāyaṇa by Paṇḍit Seu, the “Mankot” Rāmāyaṇa and the “Siege of Laṅkā” by Mānaku in the light of the text from the Vālmīki Rāmayaṇa on the versos of the paintings. This allows significant conclusions about the intentions behind their production and the original extent of each set.
Verses at the Court of the King: Shifts in the Historical Imagination of the Sanskrit Literary Tradition during the Second Millennium
Authors: ALI DAUD
Published: October 2021

This essay argues that the rise and circulation of large numbers of Sanskrit literary anthologies as well as story traditions about poets in the second millennium together index important changes in the ‘author-function’ within the Sanskrit literary tradition. While modern ‘empirical authorship’ and external referentiality in Sanskrit has long been deemed ‘elusive'by Western scholarship, the new forms of literary production in the second millennium suggest a distinct new interest in authorship among wider literary communities. This new ‘author-function’ indexed a shift in the perceptions of literary production and the literary tradition itself. Focusing on the famous sixteenth-century work known as theBhojaprabandhaas both an anthology as well as a storybook about poets, this essay further argues that the paradigmatic courts of kings like Vikramāditya and Bhoja (but particularly the latter), placed not in historical time but in an archaic temporality, became themise en scènefor the figure of the poet in the second-millennium literary imagination. They were courts where the finest poets of the tradition appeared and where their virtuosity could be savored and reflected upon by generations of readers.
Economic Inequality and Political Responsiveness: A Systematic Review
Authors: Elkjær Mads Andreas , Klitgaard Michael Baggesen
Published: October 2021

Do political outcomes respond more strongly to the preferences of the rich? In an age of rising inequality, this question has become increasingly salient. Yet, although an influential literature has emerged, no systematic account exists either of the severity of differentials in political responsiveness, the potential drivers of those differentials, or the variation across democracies. This article fills that gap. We analyze 1,163 estimates of responsiveness from 25 studies and find that, although this research collectively suggests that political outcomes better reflect the preferences of the rich, results vary considerably across models and studies. The divergence in results is partly driven by partisanship and the model specification, while we find no significant variation across either policy domains or general/specific measures of political outcomes. Finally, and against theoretical expectations, published research suggests that differentials in responsiveness are weaker in the United States compared to other developed democracies. The article contributes to our understanding of differential responsiveness by clarifying the main debates and findings in the literature, identifying issues and gaps, and pointing to fruitful avenues for future research.
Legal pluralism and stigma: a case-study of customary resurgence in the Chakma communities of Bangladesh and India
Authors: O'Brien Margaret
Published: October 2021

This paper explores the complex iteration of ethnic identity and legal culture amongst the Chakma peoples of the Chittagong Hill Tracts of Bangladesh and the hill territories of Tripura, India. Its hypothesis is that the stigma of tribal identity is more likely to be sustained in situations of ‘weak’ pluralism – that is, where the customary system is formally annexed to the state. However, such stigma is more likely to be dispelled where numerous, competing legal jurisdictions collide in a ‘strong’ pluralism expressed as a relatively autonomous legal domain, overlapping legal jurisdictions and in the presence of a productive and potentially creative ‘interlegality’. Conversely, strong state recognition of identities, such as can be found in India, appears to be linked to weak local pluralism, creating an insular and inward-looking community that embraces stigma and the preservation and use of customary practices. In conclusion, this paper asserts that formal state recognition in a situation of legal pluralism tends to freeze identities in a facsimile of the colonial trope of tribe, whilst conflict between the communities and the state generates new and resistant identities and new iterations of customary law.
Feedback-Seeking Behavior in Organizations: A Meta-Analysis and Systematical Review of Longitudinal Studies
Authors: Bălăceanu Alexandra , Vîrgă Delia , Maricuțoiu Laurentiu
Published: October 2021

Based on the Job Demands-Resources theory, this meta‐analysis investigates the role of resources in predicting feedback-seeking behavior (FSB) over time. We also examine the relationship between FSB and its outcomes from a systematic review perspective. The eligibility criteria were: (a) to measure feedback-seeking behavior, (b) to have a longitudinal design, and (c) to have employees as target groups. Thirteen studies met these criteria (Ntotal= 1,527). We combined the meta-analysis procedures and structural equation modeling (metaSEM) and used the systematic review. The methodological quality of the available longitudinal studies is assessed. Our findings indicated that job resources predict future feedback-seeking behavior and between feedback-seeking behavior and personal resources is significant relationship. More research is needed to clarify the reciprocal relationships between personal resources and feedback-seeking behavior and the influences of feedback-seeking behavior on performance.