bluuebunny/crossref_metadata_2025 huggingface dataset:
Der Brexit und die ökonomischen Folgen für das Vereinigte Königreich
Authors: Smeets Dieter
Published: September 2024

Während das Vereinige Königreich (VK) am 31. Januar 2020 aus der EU austrat (Brexit), erfolgte der Austritt aus dem EU-Binnenmarkt erst nach einer Übergangsphase am 1. Januar 2021. Seither kam es zu einem deutlichen Rückgang des britischen Waren- und Finanzdienstleistungshandels gegenüber der EU und Deutschland. Im Gegensatz dazu ist die gesamtwirtschaftliche Entwicklung des VK seit dem Brexit nicht gravierend anders verlaufen als in Deutschland. Offen bleibt jedoch, wie sich die britische Wirtschaft seit 2016 ohne die Brexit-Entscheidung entwickelt hätte.
Der Einfluss der Migration auf die regionalen Bevölkerungsschätzungen der Vereinten Nationen
Authors: Wienert Helmut
Published: September 2024

Die Vereinten Nationen prognostizieren regelmäßig die Entwicklung der Bevölkerung in der Welt und zwar aufgegliedert nach Ländern und Regionen. Neben der natürlichen Veränderung (Geburten minus Sterbefälle) spielt dabei auch der Wanderungssaldo eine Rolle. Am Beispiel der UN-Regionen „Sub-Sahara Afrika“ und „Europa“ wird gezeigt, dass die Wanderungssalden im Prognosezeitraum bis zum Jahr 2100 vermutlich deutlich unterschätzt werden.
Wem gehört der Fußball?
Authors: Daumann Frank , Follert Florian
Published: September 2024

Die Behauptung der Fans, der Fußball gehöre ihnen, ist aus Sicht der Theorie der Verfügungsrechte unzutreffend; vielmehr gehört der Fußball den Veranstaltern.
Wettbewerbsfähigkeit Deutschlands: Handlungsdruck für Staat und Unternehmen
Authors: Paul Stephan
Published: September 2024

Die Position deutscher Unternehmen im internationalen Konkurrenzumfeld hat sich durch den besonders hohen Anteil traditioneller Industriesektoren, ihre internationale Verflechtung, die Energiekostenbelastung sowie den demographischen Wandel verschlechtert. Um gegenzusteuern, sind staatlicherseits sowie durch unternehmerisches Handeln insbesondere die Innovationskraft zu stärken und das Arbeitsangebot auszuweiten.
Die Call out-Ökonomie
Authors: Lies Jan
Published: September 2024

Märkte und Management entwickeln sich. Aktuellere Schlagworte wie „Informations-" oder „Aufmerksamkeitsökonomie“, „Economics of Persuasion“ oder „Narrative Ökonomie“ zeigen an, dass sich die Wirtschaftsgesellschaft verändert. Dieser Beitrag fragt, (1) welche Rolle Kommunikation auf Märkten und im Management spielt und (2) welche Konsequenzen sich für das Management hieraus ergeben. Hierfür werden die Entwicklungen von Markt 1.0 bis 4.0 sowie Management 1.0 bis 4.0 nachgezeichnet, um die Konvergenzen der Logiken von Markt, Management und Kommunikation zu erklären. Diese Konvergenz wird von der sich entwickelnden Organisation der Wertschöpfung angetrieben. Sie führt zur Call out-Ökonomie und den wachsenden Anforderungen der Medienkompetenz des Managements.
Nachhaltigkeitsmanagement im Mittelstand
Authors: Petersen Holger
Published: September 2024

Steigender Bedarf nach Know-how im Nachhaltigkeitsmanagement erfasst aufgrund neuer Gesetze zunehmend auch den Mittelstand. Entscheidender für die Ausrichtung ihres Kerngeschäfts auf ökologische und soziale Ziele sind jedoch Umsatzpotenziale in Wachstumsmärkten, die von Nachhaltigkeitspionieren seit den 70er Jahren erschlossen werden. Dieser Beitrag umreißt, wodurch Mittelständler ihre Vorteile nutzen können, um im Einklang mit ökonomischen Zielen zum Erhalt des Natur-, Sozial- und Humankapitals beizutragen.
Das Myerson-Lösungskonzept
Authors: Hiller Tobias
Published: September 2024

In der kooperativen Spieltheorie können Graphen und Netzwerke auf der Spielermenge bei der Ermittlung der Spieler-Auszahlungen berücksichtigt werden. Das bekannteste Lösungskonzept zur Ermittlung der Spieler-Auszahlungen bei Spielen mit Graphen geht auf Myerson (1977) zurück. In diesem Beitrag werden dieses Lösungskonzept und seine in den letzten Jahren entstandenen Varianten präsentiert.
Propuesta de sílabo de un curso sobre lengua de señas peruana (LSP) para Lingüística en la UNMSM
Authors: Bardales Sihue Rosa Milagros , Berrocal Guerra Juan Diego , Saravia Durand Sonia
Published: September 2024

Atualmente, apesar do reconhecimento legal da Língua de Sinais Peruana (LSP) como língua oficial e nativa, os cursos do currículo oficial do curso de Linguística da UNMSM concentram-se na pesquisa em línguas orais ou escritas. Portanto, este artigo tem como objetivo desenvolver uma proposta de programa de estudos para a disciplina Gramática de uma Língua de Sinais I a fim de incentivar a pesquisa em LSP nos alunos de Linguística de San Marcos. Metodologicamente, é utilizado um modelo de programa de estudos voltado para o ensino da linguística da língua de sinais (Esipova e Buchholz, 2020), bem como uma bibliografia que apresenta conteúdo relevante para a organização dos tópicos (Baker et al., 2016; Brentari, 2019; Sandler y Lillo-Martin, 2006), e uma abordagem de aprendizagem baseada em investigação (Santana-Vega et al., 2020). As informações consideradas para o curso foram divididas em quatro unidades que levam em conta a orientação do professor no processo investigativo proposto pelos alunos por meio de consultorias personalizadas. Em conclusão, argumenta-se que o programa de estudos proposto precisa ser enquadrado em um contexto de pesquisa. Por fim, reconhece-se a importância de criar outros cursos no futuro que possam complementar os tópicos e níveis abordados no LSP.
Tutoría como estrategia sistémica para desarrollar las destrezas investigativas en estudiantes sordos en la UNAN-Managua, Nicaragua
Authors: Peña Ruiz Estrella Luz
Published: September 2024

La tutoría es una estrategia implementada por muchas instituciones educativas, institucionalizada e incluida dentro de las funciones de los docentes, normada por los reglamentos internos. Está constituida como estrategia macro para promover mayor aprendizaje en estudiantes sordos. Consiste en integrar a las personas sordas y ayudarles a comprender el contenido del componente de la carrera cursa, integrarlos al grupo clase y a la evaluación formativa. La tutoría es más que un repaso de una temática, pues está diseñada estratégicamente para mejorar destrezas investigativas, superar las barreras cognitivas entre la teoría y la práctica, solucionar desfases de vocabulario, atender el poco uso de las bases de datos y enriquecer procesos de adquisición de escritura en L2. Además, coadyuva al docente y al estudiante a trabajar aspectos como el socioafectivo, los estilos de aprendizajes y las habilidades cognitivas; por tanto, consecuentemente, es una plataforma de aprendizaje sistémico. Metodológicamente, se aplica el paradigma interpretativo, cualitativo, a través de los métodos analítico, sintético, deductivo e inductivo. Los resultados indican que los estudiantes sordos reciben apoyo de las autoridades universitarias, pero no obtienen tutorías constantes de parte de sus docentes, falta un programa de seguimiento para potencializar los procesos de aprendizajes de las destrezas investigativas para la obtención de conocimientos metas.
Optimization of distributed control discrete systems under the quadratic quality criterion
Authors: Janušauskaitė Nijolė
Published: September 2024

The quadratic functional minimization problem was analysed. The motion trajectory was assumed to be discrete, the optimal control feedback was obtained.
The existence of solution of nonlinear problem of magnetization
Authors: Katauskis Pranas
Published: September 2024

The kinetic equations describing the magnetization of a medium consisting of single-domain particles are investigated. The local existence of solution and its uniqueness is proved.
Zur Theorie inneren Tensorstrukturen in Kawaguchischen Räumen
Authors: Mazėtis Edmundas
Published: September 2024

In einem Kawaguchischen Raum der zweiter Ordnung ist Existenz inneren dualen Tensorstrukturen be­weist, Bedingungen ihrer Integrierbarkeit festgestellt und affine Zusammenhänge, assoziierte mit diesen Strukturen, konstruiert.
Extentions et invariants différentiels dans l'espace Yn
Authors: Urbonas Algimantas Pranas
Published: September 2024

On étudie les extentions des objets différentiels – géométriques, les tenseurs normales et invariants différentiels dans l'espace Y.
Application programme interface to deductive database
Authors: Čaplinskas Albertas , Milašauskas Mindaugas
Published: September 2024

The paper discusses midleware that implements application programme interface to deductive database. New approach is proposed how to implement the application programme interface of such kind.
Essentials of operations on files and directories in teaching
Authors: Dagys Viktoras , Grigas Gintautas
Published: September 2024

The transition towards more sofisticated knowledge of data classification, arrangement, coding, and processing at the level of files and directories may be achieved by means of separation goals from tools and concentration on goals. So the tool must be simple to learn and universal to cover all desired goals. The Windows Commander was used as a tool for discussion.
Mathematics teachers' and student teachers' attitudes towards mathematics teaching in comparison
Authors: Būdienė Virginija
Published: September 2024

This article deals with the study on attitudes of Lithuanian mathematics teachers and student teachers towards math education. The objective of the study is to determine the level and differences of basic concep­tions of Lithuanian math teachers and students, and to compare with conceptions of Estonian and Finnish mathematics  teachers. The research is based upon the typology of concepts introduced by J. Dionne (1984). The common math education culture of teachers and student teachers is discovered. The discussion on revealed similarities and differences is presented.
Mathematics education and teaching materials in Lithuania
Authors: Būdienė Virginija , Stričkienė Marytė
Published: September 2024

This paper addresses issues in the use of new generation of teaching materials in mathematics education in Lithuania. The principles of current policy on textbook writing and experimental implementation is examined. By reflecting on teacher's attitudes survey assumption is made on the influence of new textbooks on mathematics instruction.
From the history of the Department of Mathematics at the Agricultural University of Lithuania
Authors: Kaminskienė Janina , Liubertienė Janina
Published: September 2024

The article is dedicated to the 50 years anniversary of the Mathematics Department. The foundation's history is described there. All the heads of the Department and their biographies are mentioned in this article. The main directions of scientific work and methodical work are analysed.
On decidability of a fragment of intuitionistic predicate logic
Authors: Kaušilaitė Jolanta , Pliuškevičius Regimantas
Published: September 2024

There is not abstract.
Econometric modelling of the Lithuanian economic indicators
Authors: Kalinauskas Žilvinas
Published: September 2024

The paper is devoted to model relations between Lithuanian indicators of production, foreign trade, income and prices and to present short-term forecasts. The join behaviour of Lithuanian GDP, exports and imports of goods and services, money, salaries and prices is examined by the structural vector auto-regression models (SVAR). Striving for the larger accuracy, apart the aggregated indicators their components are analysed as well.Economic literature and experience of practical work show that there is relation between GDP, foreign trade, money and income indicators and unemployment. It was refer to Blanchard's work where he uses SVAR models to analyse GDP, consumer price index, money M1, wages and unemployment indicators. Unemployment was refused from a vector of Lithuanian economic indicators because the data from the Lithuanian labour exchange are unreliable. At the first stage there was limited oneself the detailed analysis of GDP and foreign trade indicators.After the Russian crisis some relations between economic indicators do not observe in Lithuania. The­refore, forecasts that we calculated by using previous VAR models were not correct, and we had to change these models to the others, to look for new methods. One of them – to decompose GDP into separate parts (components) and forecast them separately.In Lithuania it is seen that economic indicators are strongly cointegrated at the highest level of aggre­gation. These relations survived stable in period of the Russian crisis. For instance, GDP is cointegrąted with export and wages. That is why other alternative for SVAR models would be vector error correction model (VECM).Co-ordination of those two methods is possible. The primary forecast, which was calculated as the sum of forecasts of components, is made more exactly, taking into account the residual of cointegration.At the end of this research some results are presented, and the forecasts of GDP that were calculated using three methods mentioned above are compared to each other.
Adaptive integration algorithm for stiff ordinary differential equations
Authors: Čiegis Raimondas , Suboč Olga
Published: September 2024

The accuracy of one adaptive integration algorithm is investigated. The accuracy of the discretization is estimated by comparing the discrete and exact stability factors. It is proved that the classical stiffness definition is sufficient for explicit schemes. The complexity of implicit schemes depends on the distribution of eigenvalues of the systems matrix and the information about minimal and maximal values of eigenvalues is not sufficient. Results of numerical experiments are presented.
The stability of the press plate by creep theory
Authors: Bartaševičius Algimantas
Published: September 2024

According to creep theory incurves of pressed plate increasing during the time. It means that defor­mated plate is not stable.
Some inequalities in the arithmetic semigroups
Authors: Bareikis Gintautas
Published: September 2024

There is not abstract.
Discrete limit theorems for trigonometric polynomials
Authors: Kačinskaitė Roma
Published: September 2024

There is not abstract.
Local distributions of multiplicative functions
Authors: Skrabutėnas Rimantas
Published: September 2024

In the present paper the local distribution laws of values of multiplicative arithmetic functions g : G → R defined on arithmetical semigroups G and belonging to the class M(G) is considered. An asymptotical expansion for the main term in local limit theorem is obtained.
The Crisis of the Bibliographic Department: Did Dostoevsky Write Reviews for “Grazhdanin” (“The Citizen”)
Authors: Buchneva Daria
Published: September 2024

The first part of the novel “Alexey Slobodin. Family History” was published in the 10th, 11th and 12th issues of “Vestnik Evropy” for 1872, under the pseudonym P. Al’minsky (A. I. Pal’m). A critical review of Pal’m’s work was posted anonymously in “Grazhdanin” (“Citizen”) (1873, no. 1). In his notebook, F. M. Dostoevsky entrusted the writing of the review to V. P. Meshchersky. In 1935, E. N. Konshina linked the writer’s note with a review of Pal’m’s novel. V. V. Vinogradov was the first to declare Dostoevsky’s authorship. The researchers tried to resolve the issue unambiguously: it was either Dostoevsky or Meshchersky. However, Dostoevsky’s editorial work involved various forms of interaction. Review of “Alexey Slobodin. Family History” is based on the concept of artistic types, which was developed by Dostoevsky. He tasked Meshchersky with writing the review and provided him with a review plan. There are several fragments in the critical review that make it possible to recognize Dostoevsky as a co-author. Thus, an appeal to the of Savely Tuberozov type precedes the review of the novel by N. S. Leskov (Stebnitsky) “Soboryane” published in the fourth issue. There is a similarity in the description of this image. In his analysis of Leskov’s work Dostoevsky reveals the concept of type in more detail than Meshchersky. The controversy with A. N. Pypin, presented in the article on the novel “Palma,” also belongs to Dostoevsky. The style is noticeably incosistent, which indicates that the text resulted from the simultaneous work of two authors: Meshchersky and Dostoevsky. The article presents additional arguments in favor of the fact that Dostoevsky was one of the authors of the review of Leskov’s novel “Soboryane.” The mathematical methods used in this study confirm this hypothesis.
Automatic alignment of elastic slender belt caused by crown roller in two-roller belt system
Authors: Yoshida Kazushi , Suetomi, Anjyu , Kawamata Hayato , Nakamichi Yu
Published: September 2024

To clarify the relationship between the geometry of the crown roller and the automatic alignment of the belt in a two-roller belt system that includes a crown roller, we develop an analytical method that calculates the lateral belt position. The calculated results based on this method are in good agreement with the experimental results, thereby validating the analysis method developed. The automatic alignment of the belt is caused by the difference in the peripheral speed of the crown roller in the axial direction. The automatic alignment effect improves as the radius of curvature and the diameter of the crown roller decrease. Furthermore, we show that the effect of belt tension on the automatic alignment of the belt has a slight effect on the time until the belt moves to the roller center position but does not have a significant effect on the automatic alignment of the belt.
Genes of Streptomyces globisporus 1912-4Crt Encoding Chitin Catabolism Enzymes
Authors: Polishchuk L.V.
Published: September 2024

Polysaccharide chitin is one of the most common biopolymers in nature. Chitin (when used as the sole source of energy, carbon, and nitrogen) has been shown to be a substrate sufficient to enable the growth and synthesis of secondary metabolites by the S. griseus NCIMB 8136 strain and some other streptomycetes. The species Streptomyces globisporus and S. griseus belong to the same lower hierarchical taxon (S. griseus clade). The aim was to find in the S. globisporus 1912-4Crt genome genes encoding proteins that are necessary for chitin fermentation and transmembrane transport of resulting products. Methods. The object of the study was a sequence of the S. globisporus 1912-4Crt genome (reference NZ_QWFA01000000.1, GenBank) on the server of NCBI (The National Center for Biotechnology Information). Streptomycete S. globisporus 1912 and its variants are producers of antibiotic landomycin E and carotenoids. Search for and analysis of nucleotide and amino acid sequences were performed using programs BLAST (Basic Local Alignment Search Tool) on the aforementioned server. Results. A set of genes that determine enzymes of chitin catabolism and Ngc-transporter proteins were identified in the S. globisporus 1912-4Crt genome. Genes encoding 10 endo-acting chitinases (from the GH18 and GH19 families) and 2 exo-acting hydrolases (GH20) were identified in the S. globisporus 1912-4Crt sequence. Several genes determining deacetylases that deacetylate both chitin and oligosaccharides were found in the genome of the strain. One gene that determines endo-acting chitosanase from the GH75 family was discovered there. The ability of the wild-type strain S. globisporus 1912 and a number of its variants (including S. globisporus 1912-4Crt) to ferment chitin was proven in vitro. Conclusions. A set of genes sufficient for chitin assimilation was established in the S. globisporus 1912-4Crt genome sequence.  Streptomycetes from different clades (for example, strains of S. coelicolor (S. albidoflavus group) and S. griseus, S. globisporus (S. griseus group)) containing different complexes of chitinolytic enzymes could be suggested.
The Use of Personalized Pharmabiotics as an Approach to the Rehabilitation of Post-COVID Patients
Authors: Yusko L.S. , Burmei S.A. , Lemko I.S. , Krastanov A.I. , Boyko N.V.
Published: September 2024

Successful application of defined pro- and/prebiotic preparations for the prevention and treatment of viral respiratory infections is confirmed by meta-analyses and numerous clinical trials. To date, the protocols for the rehabilitation of patients with post-COVID conditions, an integral part of which is the restoration of the balance of gut microbiota along with nutritional supportу, are widely developed and accepted. Purpose. To investigate the efficacy of individually prescribed pharmabiotics for targeted correction of the nasal and gut microbiota of post-COVID-19 patients in combination with aerosol inhalations. Methods. The post-COVID-19 patients were referred to recover using the rehabilitation facilities. In addition to the basic treatment complex, the patients were offered haloaerosol therapy with an additional prescription of individually selected pharmabiotics. Results. The use of individually prescribed pharmabiotics in combination with aerosol inhalation enabled therestoration of Lactobacillus spp. balance and reduction in the number of opportunistic microbiota in the gut. Thus, the personalized rehabilitation approach led to significantly improved local immune response in post-COVID-19 patients. Conclusions. The data obtained provide supportive evidence of the efficacy of aerosol inhalations and personalized pharmabiotics Lactobacillus rhamnosus S25 and L. plantarum A combined application in the directed modulation of the microbiome and targeted correction of local immunity in post-COVID patients. Restoring the balance of the patient’s' oral and gut microbiota should be an integral part of the post-COVID patient’s rehabilitation.
Effect of Convective Drying and Far-Infrared Radiation on the Physical Properties and Microstructure of Yacón Chips (Smallanthus sonchifolius)
Authors: Baldeón Edwin O. , Bracamonte-Herrera Álvaro , Soto-Torres Andrés , Salas-Valerio Walter F. , Vidaurre-Ruiz Julio Mauricio
Published: September 2024

Convective drying is widely used in the food industry due to its simplicity and versatility, as it allows for better temperature control and heat distribution, which is essential for maintaining product quality. However, this method can be slower compared to infrared drying.  The aim of this research was to evaluate the effect of convective and infrared drying on the physical properties and microstructure of yacón chips. An infrared dryer and a convection dryer were used to this effect, setting temperatures of 60, 70, and 80 °C for both methods. The color and texture properties, as well as the microstructure, changed with the increase in temperature. The greatest color variation in the yacón samples was reported by infrared drying at a temperature of 80 ° C. Regarding texture, there were no differences between the two methods. The microstructure of the yacón samples dried by hot air exhibited more significant cell damage, especially at 60 °C, in comparison with infrared drying, which showed a more microporous and compact structure. The results indicate that the method used impacted shrinkage: infrared drying produced a higher level of shrinkage when compared to convective drying. It is important to note that this is a significant physical change that can adversely affect the quality of dehydrated food.  Infrared drying produced greater rehydration in comparison with convective drying. Similarly, improved rehydration was observed at a temperature of 70 ºC. In conclusion, the infrared drying method, coupled with appropriate drying conditions, constitutes a good alternative for drying yacón chips.
Relación parental y rendimiento académico de un grupo de estudiantes de primaria en una escuela pública de Lima, Perú
Authors: Gastello Mathews Willy
Published: September 2024

El objetivo de la investigación fue establecer la correspondencia entre la relación parental y el rendimiento académico en estudiantes de primaria de una escuela pública en Lima, Perú. La hipótesis general fue: existe relación significativa entre relación parental y rendimiento académico en estudiantes de primaria de una escuela pública en Lima, Perú. La investigación se llevó a cabo en función de una problemática latente en las escuelas públicas de Perú en vínculo con el rendimiento académico del estudiantado, la cual presenta como condicionante la relación parental, lo cual implica una repercusión directa en el éxito escolar. Para tal efecto, se empleó una metodología de enfoque cuantitativo, no experimental – transversal y de alcance correlacional. Para obtener la información, se empleó como técnica a la encuesta. Se usó como instrumentos el cuestionario y el registro de notas del período 2023, los cuales fueron procesados por medio de la estadística descriptiva e inferencial, se aplicó para este último Rho de Spearman para comprobar la relación entre las variables. Los resultados descriptivos informaron que el 43 % de las personas participantes percibe que la relación parental es buena; mientras que el 83 % obtuvo un nivel en proceso, esto en cuanto al rendimiento académico en términos de logro de aprendizaje. En los resultados inferenciales se encontró relación entre las variables de Rho: ,548; p= ,002; asimismo, se halló significancia en las pruebas de hipótesis específicas. Se concluyó que existe correlación significativa entre la relación parental y el rendimiento académico en estudiantes de primaria en una escuela pública de Lima, Perú. Por tanto, cuando los vínculos entre la familia y su descendencia se encuentran en las mejores condiciones, el estudiantado se siente apoyado y confiado para obtener un buen rendimiento académico.
From passion to knowledge
Authors: Kovács Dániel Attila
Published: September 2024

In this paper, I aim to situate the practical agency of the sage in an overall picture of the development of the Plotinian moral agent. This development can be seen as a gradual transition from external to internal principles of action guidance which endow the agent with autonomy and coherence in her practical actions. The transition from external to internal principles corresponds to a changing relationship between the agent's telos and particular actions. Non-virtuous agents aim at the attainment of an object of desire, while the civically virtuous person aims to perform virtuous actions irrespectively of the achievement of particular objects of desire. Finally, the telos of the sage is the contemplation of forms and she acts practically as a consequence and external activity of having achieved her goal. The analysis of Plotinus' theory of moral development shows that the sage's inward turn and detachment from external circumstances do not involve inactivity in the practical sphere but figure as a necessary condition of her making an active contribution to the order of the sensible world through her actions as opposed to passively responding to external circumstances.
“An Era More than Bleak”
Authors: Péteri Lóránt
Published: September 2024

Ferenc Farkas, a remarkable twentieth-century Hungarian composer, was one of the most influential professors of composition throughout the history of the Liszt Academy of Music, Budapest. A less known chapter of his life is his involvement in the ethnicist and anti-Semitic political movements of Hungary, during the late 1930s and early 1940s. In 1940, he was among three musicians who elaborated a proposal to establish, in line with the rise of corporatism, a Hungarian Music Chamber. One of the main aims of the new organization would have been a total exclusion of Jewish musicians from all branches of Hungarian musical culture. The Chamber was never actually founded. In 1941, Farkas left Budapest for the Transylvanian city Kolozsvár (Cluj), where he was appointed professor of composition at the Conservatory. One of his first students was György Ligeti, a native Transylvanian, born into a Hungarian family suffering under the anti-Semitic legislation of the Hungarian state. As Ligeti recollected, Farkas “wanted to teach me everything he had learned from his teacher Ottorino Respighi.” Based on archival sources, this study offers new insights into the personal and professional connection between Ligeti and Farkas during the 1940s, and also follows Farkas's post-war path from relative isolation and marginalization to the elite of state socialist music culture.
Core stability exercise for the impact of weightlifting and deadlifting on herniated nucleus pulposus (HNP): a systematic review
Authors: Hartatik Ni Made Ayu Sri , Wardhana Dewa Putu Wisnu , Dharma Bagus Diva Indra
Published: September 2024

Background: Herniated nucleus pulposus or disc herniation is a serious medical condition, the common cause of sciatic pain, and the most common indication for spine surgery. People doing athletic sports, especially weightlifting and deadlifting, may face significant acute and overuse spinal injuries that can cause HNP. Core stability exercise (CSE) improves athletes' sports performance and can prevent injury. This systematic review aims to determine the impact of core stability exercises on weightlifting and deadlifting on herniated nucleus pulposus.
Method: According to PRISMA recommendations, a systematic review using an online database was carried out. The inclusion criteria set includes studies regarding the impact of core stability exercise on deadlifting and weightlifting to prevent HNP, using adult samples>18 years old and providing the type of CSE exercise. In contrast, the exclusion criteria were studied not available in full text and not available in Bahasa or English. Study quality assessments were done using a checklist for the Joanna Briggs Institute.
Result: Ten studies are included in this systematic review, consisting of six randomized controlled trials, two review articles, one case-control study, and one prospective cohort study. The CSE effectively improves the endurance, strength, mobility, and dynamic balance of core muscles, especially spinal muscles, which can prevent back injury, especially for weightlifters and dead lifters. Core stability exercises should be incorporated into athletes' training programs to improve sports performance and reduce the risk of back injury, especially HNP.
Conclusion: The CSE effectively improves the endurance, strength, mobility, and dynamic balance of core muscle, especially spinal muscle, which can prevent back injury in athletes, especially weightlifters and dead lifters.
Pott’s disease and scrofuloderma as presentation of clinically extrapulmonary tuberculosis in 15 years old girl: a case report
Authors: Soesanto Davit , Purniti Ni Putu Siadi , Subanada Ida Bagus , Suwarba I Gusti Ngurah Made , Mahalini Dewi Sutriani , Winarti Ni Wayan
Published: September 2024

Backgrounds: Extrapulmonary tuberculosis (TB) accounts for 15–20% of all tuberculosis cases, with the lymph node being the most commonly affected organ. Spinal tuberculosis and scrofuloderma are rare manifestations of extrapulmonary TB and constitute less than 5% of the cases. Establishing the diagnosis is a challenge. Eradication and prevention of sequelae complicate further management of the disease. This study aims to describe the clinical manifestation and the management of spondylitis tuberculosis and scrofuloderma in a child.
Case presentation: A 15-year-old girl came with a chief complaint of lower extremities weakness for a week following monthly chronic low back pain. She also reported a painless lesion on her back with no sign of acute inflammation. She also complained of intermittent fever with night sweats and lost 3 kilos of body weight in the last two months. From physical examination, we found a kyphotic posture and severe malnutrition. Skin examination revealed an open wound on her right lower back, size 4x3 cm, with no sign of inflammation. The tuberculin skin test was positive with 15 mm induration. The spinal magnetic resonance imaging revealed destruction of the vertebral corpus thoracal segment, hyperintense sacrum, and right ileum bone with a cold abscess, suggesting spondylitis TB. A wound biopsy with hematoxylin-eosin stain concluded chronic granulomatous inflammation and showed multinucleated giant cell Langhans-type, suggestive of cutaneous tuberculosis. Microbiology examination (PCR GeneXpert) from wound biopsy and ziehl neelsen stain failed to detect Mycobacterium tuberculosis. The patient was diagnosed with Pott’s disease and scrofuloderma. Anti-tuberculous therapy commenced, and the patient responded well after several months of treatment.
Conclusions: The diagnosis of extrapulmonary TB manifests as spinal tuberculosis, and scrofuloderma could be made from clinical manifestation and imaging.
Long-term assessment of functional outcome in operated cases of Hirschsprung disease
Authors: Poerwosusanta Hery , Willyanto Nathan Aditya
Published: September 2024

Background: Hirschsprung disease (HD) is a rare congenital anomaly (1 in 5000 live births) characterized by varying levels of aganglionosis. The evolution of surgical options and outcomes for the successful management of HD has been driven by the aspiration of pediatric surgeons. Hirschsprung's disease postoperative results of pull-through procedure could be influenced by surgical and pathological proficiency and the quality of perioperative care. Controversies persist as to which technique offers the best outcome. The absence of incontinence and constipation remains the most important marker of a good outcome. 
Methods: Medical records of HD children who underwent temporary colostomy procedures were analyzed retrospectively from July 2017 to June 2021. Risk factors were evaluated to determine the outcome of HD procedures.
Results: Ninety-two HD patients were included. Based on the univariate analysis, most patients in the study (58.7%) were between the ages of 2 and 12 months. The study population predominantly consisted of males (68.5%) who had low vegetable intake (65.2%) and occasionally exhibited stool stains (66.3%), but their stool consistency was mainly normal (47.8%). Further examination through bivariate analysis revealed a significant negative correlation between stool stains and SOAVE (name of the condition). Similar findings were observed for stool consistency, indicating a significant correlation. Consequently, both variables were subjected to multivariate analysis. The multivariate analysis demonstrated a significant association between stool consistency and SOAVE among patients aged 2-12 months (p=0.000, OR =2.044E-7) and those aged 1-5 years (p=0.000, OR =2.044E-7). An odds ratio (OR) value of less than 1 implies that individuals with normal stool consistency have a lower likelihood of experiencing SOAVE at a young age.
Conclusions: This study showed that children with HD correlated with low daily vegetable intake. Normal feces were associated with higher SOAVE ages and a lower possibility of experiencing SOAVE at a young age.
Terapi thrombopoietin receptor agonist pada pasien immune thrombocytopenia dengan infeksi COVID-19: sebuah laporan kasus
Authors: Permana I Gede Komang Aditya , Rena Renny Anggreni
Published: September 2024

Background: Coronavirus disease 2019 (COVID-19) is a serious health problem in many parts of the world. COVID-19 may trigger a new presentation of Immune Thrombocytopenia (ITP) or may cause relapse in patients with chronic ITP. Treatment of ITP in COVID-19 patients has the risk of worsening the condition of COVID-19 itself.
Case presentation: A 32-year-old male with a history of chronic Immune Thrombocytopenia (ITP) was confirmed with COVID-19. The condition of ITP is controlled with low-dose steroids, presents with very low platelets, and does not respond to previous treatment; it was later discovered that the patient was infected with COVID-19. COVID-19 is known to aggravate thrombocytopenia in patients with ITP and can lead to new ITP conditions. Recent guidelines state that intravenous immunoglobulin (IvIg) is the first choice in ITP patients who have COVID-19 infection, and thrombopoietin receptor agonist (TPO-RA) was another alternative treatment, in this case, the patient received platelet transfusion therapy and TPO-RA, reported that the patient's platelets were well controlled with the use of TPO-RA and COVID-19 infection also improved with the treatment.
Conclusion: Swift diagnosis is needed to improve the quality of life of patients and minimize the occurrence of potential complications caused by COVID-19 in chronic ITP patients.
 
Latar Belakang: Coronavirus disease 2019 (COVID-19) merupakan masalah kesehatan yang serius di berbagai belahan dunia dan Organisasi Kesehatan Dunia (WHO) telah menetapkan COVID-19 sebagai pandemi. COVID-19 diketahui menyebabkan gejala pernafasan dengan manifestasi ringan hingga berat dan melibatkan berbagai sistem tubuh seperti hematologi, neurologi, dan sistem kekebalan tubuh.
Presentasi kasus: Seorang laki-laki berusia 32 tahun dengan riwayat Immune Thrombocytopenia (ITP) kronis terkonfirmasi mengidap COVID-19. Kondisi ITP dikendalikan dengan steroid dosis rendah dan datang dengan trombosit yang sangat rendah serta tidak merespons pengobatan sebelumnya, kemudian diketahui bahwa pasien tersebut terinfeksi COVID-19. COVID-19 diketahui memperburuk trombositopenia pada pasien ITP dan dapat menyebabkan kondisi ITP baru. Pedoman terbaru menyatakan bahwa imunoglobulin intravena (IvIg) merupakan pilihan pertama pada pasien ITP yang mengalami infeksi COVID-19, dan agonis reseptor trombopoietin (TPO-RA) merupakan pengobatan alternatif lain, dalam hal ini pasien mendapat terapi transfusi trombosit dan TPO-RA. Setelah terapi dilaporkan bahwa trombosit pasien terkontrol dengan baik dengan penggunaan TPO-RA dan infeksi COVID-19 juga membaik dengan pengobatan.
Kesimpulan: Diagnosis yang cepat diperlukan untuk meningkatkan kualitas hidup pasien dan meminimalisir terjadinya potensi komplikasi akibat COVID-19 pada pasien ITP kronis.
Efficacy of motor relearning programme on rehabilitation of upper extremity function in stroke patients
Authors: Dananjaya I Made Dwi , Silakarma Dedi , Dewi Made Yudha Asrithari
Published: September 2024

Background: The most debilitating condition for stroke patients, impacting their quality of life, is motor impairment in the upper extremities. This study aimed to evaluate the impact of the Motor Relearning Programme (MRP) on enhancing stroke patient’s upper limb motor function.
Methods: A systematic review using trial studies from an online journal database published from 2013 to 2023. The participants of this study are stroke patients. The utilization of the MRP is compared with an alternative intervention, with the study aiming to assess the motor function of the upper extremities as its primary outcome. The quality of the trial was assessed using the JBI checklist
Results: Eight studies, encompassing 279 stroke patients aged 35 to 70, were incorporated. These trials compared the MRP with various interventions, including mirror therapy, Constraint-Induced Movement Therapy (CIMT), bobath, progressive resisted exercise, thermal stimulation, and bilateral task-related training. The interventions spanned an average duration of 3-8 weeks, with sessions occurring 3-6 times per week and lasting between 30 and 120 minutes each. According to the Joanna Briggs Institute (JBI) assessment, all studies achieved a good quality rating, with total points ranging from 9-12. Notably, six studies demonstrated a significant improvement in upper extremity motor function with MRP, while one showed no significant difference. In contrast, one study indicated that CIMT demonstrated more effective results.
Conclusion: MRP significantly improves upper extremity function in stroke patients.
Uji aktivitas antibakteri ekstrak etanol daun pegagan (Centella asiatica) terhadap bakteri Streptococcus pneumoniae secara in vitro
Authors: Purba Rizky , Hendrayana Made Agus , Budayanti Ni Nyoman Sri , Fatmawati Ni Nengah Dwi
Published: September 2024

Background: The gotu kola plant (Centella asiatica) is one of the herbal ingredients used throughout the world. This plant contains triterpenoids and saponins which have broad therapeutic functions. Streptococcus pneumoniae has become a global problem that causeing community acquired pneumonia the most in the world. Our study investigate further the antibacterial activity of ethanol extract of Centella asiatica leaves to inhibit Streptococcus pneumoniae bacteria.
Methods: The Kirby-Bauer method was used to test the antibacterial activity of gotu kola (Centella asiatica) extract in this study. This is done by measuring the diameter of the inhibition zone and its standard deviation.
Results: In the positive control group of Vancomycin 30 µg, the diameter of the inhibition zone was found to be 26.7 mm, 27.15 mm and 28.05 mm. At concentrations of 25%, 50% and 75% of gotu kola leaf (Centella asiatica) ethanol extract, no antibacterial activity was found. Meanwhile, inhibition zone diameters of 8.3 mm, 8.4 mm, and 8.1 mm were found in the ethanol extract of gotu kola leaves (Centella asiatica) with a concentration of 100%.
Conclusion: Based on the results obtained, the concentration of 100% ethanol extract of gotu kola leaves (Centella asiatica) has antimicrobial activity but is unable to inhibit the growth of Streptococcus pneumoniae bacteria.
 
Latar Belakang: Tanaman pegagan (Centella asiatica) merupakan salah satu bahan herbal yang digunakan di seluruh dunia. Tanaman ini memiliki kandungan utama triterpenoid dan saponin yang berfungsi sebagai terapeutiknya yang luas. Streptococcus pneumoniae adalah bakteri yang secara historis menjadi patogen paling umum yang menyebabkan pneumonia komunitas di seluruh dunia. Penelitian mengevaluasi lebih lanjut terkait aktivitas antibakteri ekstrak etanol daun pegagan terhadap bakteri Streptococcus pneumoniae.
Metode: Metode Kirby-Bauer digunakan untuk pengujian aktivitas antibakteri ekstrak pegagan (Centella asiatica) pada penelitian ini. Hal ini dilakukan dengan mengukur diameter zona hambat dan standar deviasinya.
Hasil: Pada kelompok kontrol positif Vancomycin 30 µg, ditemukan diameter zona hambat sebesar 26,7 mm, 27,15 mm, dan 28,05 mm. Pada konsentrasi ekstrak etanol daun pegagan 25%, 50%, dan 75% tidak ditemukan aktivitas antibakteri. Sedangkan, diameter zona hambat sebesar 8,3 mm, 8,4 mm, dan 8,1 mm ditemukan pada ekstrak etanol daun pegagan (Centella asiatica) konsentrasi 100%.
Kesimpulan: Penelitian ini menunjukkan bahwa konsentrasi ekstrak etanol daun pegagan (Centella asiatica) 100% mampu menunjukan aktivitas antimikroba tetapi tidak dapat menghambat pertumbuhan bakteri Streptococcus pneumoniae.
Prevalensi polimorfisme gen reseptor vitamin D FokI Rs2228570 pada penderita kusta tipe multibasiler
Authors: Rusyati Luh Made Mas , Krisnaputri Nandya Putu , Karmila I Gusti Ayu Agung Dwi
Published: September 2024

Introduction: Leprosy is still a health problem in Indonesia. Vitamin D receptors are known to affect leprosy. Polymorphism of the VDR gene can lead to deregulation of vitamin D. The study aimed to evaluate the prevalence of polymorphism of the vitamin D receptor gene FokI rs2228570 in patients with multibacillary type leprosy.
Methods: This study was a cross-sectional study with a purposive sampling method. Patients were enrolled on an outpatient basis between October - December 2023. A total of 27 patients were selected from inclusion and exclusion criteria. Gene amplification was done by using PCR and sequencing procedures. The data was analyzed using SPSS ver. 25, and a p-value ≤ 0.05 was considered significant.
Results: Based on the results of gene sequencing, it was found that the genotype VDR FokI rs2228570 is most Ff, with 13 patients (48.14%), followed by ff and FF genotypes with 8 patients (29.62%) and 6 patients (22.22%).
Conclusion: Based on research results, the prevalence of VDR FokI rs2228570 genotype polymorphism is the most commonly found variant.
 
Pendahuluan: Kusta masih menjadi permasalahan kesehatan yang terjadi di Indonesia. Reseptor vitamin D diketahui berpengaruh terhadap kusta. Polimorfisme dari gen VDR dapat menyebabkan deregulasi dari vitamin D. Penelitian ini bertujuan untuk mengevaluasi prevalensi polimorfisme gen reseptor vitamin D FokI rs2228570 pada pasien kusta tipe multibasiler.
Metode: Studi ini adalah studi dengan desain obervasional retrospektif dengan metode purposive sampling. Pasien merupakan pasien sudah sedang dalam terapi kusta yang dirawat di RSUP Prof. Dr. I.G.N.G. Ngoerah antara bulan Oktober - Desember 2023. Total 27 pasien dipilih berdasarkan kriteria inklusi dan eksklusi. Amplifikasi gen dilakukan menggunakan prosedur PCR dan sekuensing. Data dianalisis menggunakan SPSS ver. 25, dan nilai p ≤ 0,05 dianggap signifikan.
Hasil: Berdasarkan hasil sekuensing gen, didapatkan bahwa genotipe gen VDR FokI rs2228570 terbanyak adalah genotipe Ff, yakni sebanyak 13 pasien (48,14%), diikuti dengan genotipe ff dan FF masing-masing sebanyak 8 pasien (29,62%) dan 6 pasien (22,22%).
Simpulan: Berdasarkan hasil penelitian, prevalensi polimorfisme gen VDR FokI rs2228570 genotipe heterozigot Ff merupakan varian yang paling banyak ditemukan.
Platelet-rich plasma for chronic ulcers
Authors: Martalova AJ Adelia , Praharsini I Gusti Ayu Agung , Setyono Alfred , Devi Putu Akopita , Sutiawan Indry Salonika
Published: September 2024

Ulcers that do not heal for more than 3 months are defined as chronic ulcers. Due to their increasing morbidity and mortality rates, difficulty of treatment, psychological and financial burdens, chronic ulcers are considered as a significant health problem encountered worldwide. Dressings, compression bandages, debridement, skin grafts, and other conventional treatment modalities lack growth factors needed to modulate healing process, thus less healing along with constantly repeated treatments make the whole healing process expensive. Platelet-rich plasma (PRP) is an easy, reasonably-priced modality containing growth factors needed to increase the speed of tissue healing.