bluuebunny/crossref_metadata_2025 huggingface dataset:
The Determinants of Debt Load for Companies in Emerging Markets
Authors: Klestov Mark , Jindřichovská Irena
Published: November 2021

Corporate capital structure is one of the key elements of long-term development, which determines the company value.Consequently, defining the factors that influence the debt load level of a company and, hence, its capital structure is also of great importance.

In this paper we have collected a sample of data of 753 Russian companies and 292 Brazilian companies for 2020 to evaluate the influence of various factors on their debt-load level. The data was downloaded from Bloomberg database and the basis of the analysis focuses on evaluation of conventional academic theories on capital structure, and a regression analysis based on variables extracted from a set of original hypotheses.

Among our results, our analysis illustrates that individual sets of determinants differ significantly in explanatory power, and operate unequally when contrasting Russian companies and Brazilian ones. Additionally, it was established that when companies define their debt load, they do not limit themselves to a single theory of capital structure. We conclude, inter alia, that it is impossible to identify with confidence which of the examined theories companies are most likely to follow in their actions, because observed interrelations between relevant variables and debt load have indications of various academic theories.
How Patents Influence Market Value of Industrial Enterprises' Assets?
Authors: Dementev Dmitry
Published: November 2021

Scientists and engineers are continuously patenting innovative ideas such as inventions, industrial designs, and utility models. It is therefore relevant to pose the question of the influence of intellectual property in the field of innovative technologies on the market value of the assets of industrial enterprises.

We analyse the dependence of the results of intellectual activity in the field of advanced technologies on the capitalization of innovative industrial production after the adoption of the developed technologies. We consider patent landscapes, analyse research publications, and study the dependence of financial indicators on the results of intellectual activity at enterprises producing computers, optics and electronic equipment.

Our research methodology is based on the statistical analysis of the dependence of the financial results of industrial enterprises on the actual application of the results of intellectual activity to the technological process. We define the object of analysis by citing research articles and surveys from the WoS database. The patent landscape is assessed using data from commercial information systems such as Orbit Intelligence (Questel) and Amadeus (Bureau van Dijk, Moody’s Analytics) that make it possible to visually show the links between patent activity and technological trends in the computer and electronic technology industries.

The research results shall be useful for assessing the effectiveness of employing patents in manufacturing and the prospects of improving production technologies for the formation of corporate innovative technological policy.

We conclude that the use of information on patent trends is an effective tool for increasing the competitiveness of enterprises producing electronic equipment. The priority financing of innovative technologies ensures the sustainable development of the manufacturing industry and have a positive impact on the profitability of enterprise assets.
Notes on vascular plant type collections of Cyrus G. Pringle in western United States and Mexico, 1881–1884
Authors: Mauz Kathryn
Published: November 2021

Botanist Cyrus G. Pringle collected plants in the western United States and northwestern Mexico between 1881 and 1884, and distributed his specimens as ‘Flora of the Pacific Slope’. The majority of the vascular plant type collections resulting from that work have been discussed elsewhere. This note addresses type status for five additional names that were previously overlooked in Pringle’s catalogue for Arizona and California.
Diplodia and Dothiorella species (Botryosphaeriaceae: Ascomycota) from Uzbekistan
Authors: Gafforov Yusufjon , Rakhimov Davron
Published: November 2021

The first and really only significant data on Botryosphaeriaceae mycobiota from the arid and semi-arid region of Uzbekistan are presented. This study reports 27 species of Diplodia-like fungi (Botryosphaeriaceae) from the study area; nine species are newly reported for Uzbekistan. Most species of Diplodia and Dothiorella were found on host plants of the families Amaranthaceae, Asteraceae, Fabaceae, Lamiaceae, Rosaceae, and Salicaceae. An annotated list of Diplodia-like species is given, including their host plant species, notes on taxonomy, ecology, and geographical distributions. A geo-referenced distribution map is included.
On the operative treatment of urinary incontinence
Authors: Gubarev A. P.
Published: November 2021

Involuntary discharge of urine, even in those cases when it seems to be a temporary phenomenon, is always an extremely unpleasant symptom that produces a depressing impression both on the patient and those around her, and on the doctor who is awaiting help, especially when he sees that his tryings remain completely fruitless.
About milk quantity by feeders
Authors: Budin P.
Published: November 2021

n the department for undernourished 14 nurses, feeding 14 of their own children and 50 fosterlings and performing at the same time various work on separation, were exhausted and could not deliver sufficient nutritional material for the children. Then the number of undermatched babies for the same number of nurses was reduced to 40. The results were satisfactory.
Treatment of incomplete miscarriage
Authors: Kakushkin N.
Published: November 2021

In 59 cases of miscarriage, Dolris provided surgical assistance 33 times, the rest were spontaneous. The author spontaneously had 176 miscarriages in 275 cases. From the beginning to the end of these (176), 145 miscarriages were observed.
New observation of the milk of a healthy woman
Authors: Girand F.
Published: November 2021

The author's work is divided into three parts. In the first, he draws the physicochemical properties of milk. By the way, he notes the mistake of his predecessors in the study of milk - they did not quite confuse the study of colostrum (in the first 15 days of the postnatal period) with the study of real milk.
Can the chemical composition of blood serve as an indication for the recognition of recently delivered births?
Authors: Sheinis L.
Published: November 2021

The question will undoubtedly seem to the readers of J. Ak. and Zh.B., at the very least, strange, but he is not devoid of interest in characterizing the attitude of non-doctors, even if they were representatives of the court, to the medical case in general and to the errors of doctors in particular.
Open letter
Authors: Ott D. O.
Published: November 2021

Above, I have sent a letter to the under-ranked throughout the Zemsky District Administration. Fully aware that the drafting of such a difficult task as the organization of obstetric care for the rural population is beyond the power of one person and that the indications that can be made by comrades who are in close contact with the population are especially valuable, I allow myself, in addition to Zemsky to doctors, especially employees in zemstvos, with a request not to refuse to report their opinion, as well as to send statistical materials and, in general, everything directly related to the matter. It goes without saying that the copyright will be preserved, and the sent documents, if necessary, will be returned, if such a desire is declared.
A case of deformity of genital organs, which makes it difficult to determine gender and civil rights
Authors: Bellin E. F.
Published: November 2021

(Weekly, 1898, No. 8, p. 141).Little girl 24 y. Growth 169 sntm .; the structure of the skeleton is male, breast gland nѣt.
On the question of missed abortion
Authors: Raznikov. O. A.
Published: November 2021

(Ezhenednik, 1898, No. 15, p. 283).Cases of prolonged retention of dead fetuses in the uterus, the author lasts into 2 groups: the first group includes cases when fetal eggs die in the second or third month of pregnancy, to the second, when fetal death occurs on the fourth, fifth, or more late month.
Graviditas extrauterina
Authors: Gurvich B. S.
Published: November 2021

(Yezhenednik, 1898, No. 11, p. 205).Patient 40 years old, giving birth, has been suffering from pain in the lower abdomen for 4 weeks, which began suddenly and was initially accompanied by bleeding. It is not known whether there was a delay of months.
Experiments with artificial fertilization of mammalian eggs
Authors: Gruzdev V. S.
Published: November 2021

(Doctor. 1897, No. 42, p. 1199). Artificial fertilization of eggs in lower animals with success is performed both in laboratories and in a hostel, but fertilization of eggs in mammals has not yet been sufficiently studied even among physiologists. Spallanzani injected the artificially obtained material into the dog's vagina, Schenk fertilized the artificially obtained eggs in the same way and observed the changes in the last ones using a microscope, and Ott injected the rabbits into the abdominal cavity of the rabbits.
A case of sexual mania during the months of the month and female sadism
Authors: Peskov V. N.
Published: November 2021

(Doctor. 1898, No. 8, p. 219) Patient 32 years old. (father suffered drunkenly, dѣd was epileptic), gave birth correctly twice, fed.
Glandular fibromyoma with cysts, complicated by sarcoma and cancer
Authors: Ivanov N. S.
Published: November 2021

(Doctor. 1897, No. 47 and 50, pp. 1419 and 1445).On the clinical side, this case was already described earlier (Rutkovsky. A rare case of uterine cancer.
Report on cancer patients in the gynecological department of the Tiflis Mikhailovskaya hospital for two years
Authors: Sobustianskiy E. M.
Published: November 2021

(Channel, amb. IMPER. Caucasian Med. General March 16, 1898, p. 514).The report covers the time from March 10, 2896 to March 10, 1898. The total number of cancer patients during this time was 33 (5.6% of the total number of gynecological patients during the same period of time).
Another 10 observations of the delay in the uterus of the head of the fetus after decapitation, carried out on purpose or accidentally while being extracted by the legs.
Authors: Neugebauer Fr
Published: November 2021

Another 10 observations of the delay in the uterus of the head of the fetus after decapitation, carried out on purpose or accidentally while being extracted by the legs, No. 5, p. 121
Neugebauer Fr. (Warsaw). Aenus cruenta, interdum mutillans, interdum occidens. On the issue of injuries of the genitourinary organs in women during copulation
Authors: Neugebauer Fr.
Published: November 2021

Neugebauer Fr. (Warsaw). Aenus cruenta, interdum mutillans, interdum occidens. On the issue of injuries of the genitourinary organs in women during copulation (143 observations), No. 22, 23, 24, 25.
On the question of foreign bodies in the uterus
Authors: Neztgebauer Fr.
Published: November 2021

On the question of foreign bodies in the uterus (72 corresponding observations), no. 2, 3, 4, p. 51; 96; 155.
On the primary development of cancer in fibroids and on the relationship between fibroids and uterine cancer
Authors: Switalski L
Published: November 2021

On the primary development of cancer in fibroids and on the relationship between fibroids and uterine cancer, no. 6, 7 and 8.
CORRESPONDENCE
Authors: Team Editorial
Published: November 2021

A significant part of the sick women who fill the doctors' care belong to that category of suffering patients who spend the best years of their lives in bed, pouring blood into the well-known periods, or imagine an exhausted, exhausted look, thanks to long-lasting suffering and sleepless nights.
Operative vaginal delivery: outcomes for mothers and newborns
Authors: Leonova Margarita D. , Aganezova Natalia V. , Aganezov Sergey S. , Frederiks Elena V. , Dymarskaya Yulia R.
Published: November 2021

Hypothesis/aims of study. The frequency of surgical abdominal delivery in Russia, as in the world, continues to grow, reaching 29.3% in 2017. Operative vaginal delivery is an alternative to abdominal delivery in the second stage of labor. This study was aimed at analyzing the outcome of labor for mothers and newborns using different operative vaginal delivery methods.
Study design, materials and methods. We studied 293 cases of childbirth in the period from 2015 to 2018. Three groups were distinguished: (I) the main group consisting of 172 women delivered by the operation of applying obstetric forceps (OF); (II) the comparison group including 85 patients delivered by the operation of vacuum extraction (VE) with the fetal head being near the pelvic floor; and (III) the control group comprising 34 cases of vaginal birth without use of instrumental delivery. In group I, 114 patients were delivered by the low forceps operation (subgroup IA), and 60 individuals by the mid forceps operation (subgroup IB).
Results. Vaginal lacerations were found in 21.3% of cases in group I, less often less often in groups II (10.6%, p 0.05) and III (2.9%, p 0.05). Vaginal hematoma occurred in one patient of group III (2.9%) and three women of group I (1.7%, p 0.05). There were no cases of damage to the anal sphincter. The greatest blood loss was recorded in subgroup IB (554 44.9 ml), when compared to subgroup IA (473 20.7 ml; p 0.05), group II (418 24.9 ml; p 0.05), and group III (347 33.4 ml; p 0.05). There were no differences in blood loss between the outlet OF and VE groups (p 0.05). Most newborns were born in good condition (84.5%, 77.6%, and 88.2% of cases in groups I, II, and III, respectively). Cephalohematoma in newborns was more common after VE (32.9%) than after OF (9.2%, p 0.01) and in control (5.9%, p 0.01). No retinal hemorrhage was recorded in newborns. There were no significant differences in the frequency of children being transferred to the childrens hospital (7.5%, 9.4%, and 8.8% of cases in groups I, II, and III, respectively; p 0.05).
Conclusion. The use of OF is an effective and safe method of vaginal operative delivery. It does not increase the fetal injury rate, the frequency of newborn cephalohematoma being 3.5 times less than with VE. Complications of OF and VE (except for a greater number of vaginal lacerations in cases of OF), blood loss, and the course and duration of the postpartum stay in the maternity ward are comparable.
Hysteroscopic and morphological assessment of intrauterine pathology in different age periods
Authors: Sulima Anna N. , Kolesnikova Inna O. , Davydova Aleksandra A. , Kriventsov Maxim A.
Published: November 2021

The pathology of the endo- and myometrium takes the main place in the structure of gynecological diseases. The introduction of endoscopic technologies has expanded the diagnostic capabilities of the study of intrauterine pathology. The morphological method is the gold standard in diagnosing the uterine cavity pathology. A retrospective analysis of 100 video protocols of hysteroscopy and morphological data obtained in Vash Doctor Clinic Ltd., Simferopol over the year 2018 was performed. During a retrospective analysis of hysteroscopic pictures and pathomorphological findings, all patients were divided into three age groups: (I) 2535 years old (35 women); (II) 3645 years old (35 women); and (III) 4655 years old (30 women). In the early reproductive period, endometrial hyperplasia without atypia prevailed, chronic endometritis prevailing in the late reproductive period, and polyps of the uterus in the period of the menopausal transition and postmenopause.
Complete uterus didelphia and stage 3 genital prolapse during the labor of a woman at 35–36 weeks of pregnancy while using intrauterine device
Authors: Mochalova Marina N. , Kuzmina Lyubov A. , Mironenko Anastasia Yu. , Mudrov Viktor A.
Published: November 2021

A clinical case of operative delivery of a woman with stage 3 genital prolapse, which was diagnosed at 3536 weeks of gestation, is addressed in this article. The woman became pregnant while using intrauterine device. During cesarean section, the patient was diagnosed with complete uterus didelphia. In the abdominal cavity, between the two uteruses, a T-shaped intrauterine device was detected, with no signs of uterus perforation revealed.
Pregnancy outcomes in patients with uterine junctional zone thickening
Authors: Orekhova Ekaterina K. , Zhandarova Olga A. , Kogan Igor Yu.
Published: November 2021

Hypothesis/aims of study. Overcoming infertility and miscarriage in adenomyosis is a complex practical problem in obstetrics and gynecology. It is likely that one of the signs of the disease is a thickening of the transitional zone between the endometrium and the myometrium (J-zone), which can be visualized using magnetic resonance imaging (MRI). The data on the influence of the biometric characteristics of the J-zone on the course and outcome of pregnancy in patients with adenomyosis is ambiguous. This study was aimed to assess the effect of J-zone thickness on pregnancy outcomes in patients with adenomyosis.
Study design, materials and methods. This is a prospective study, which included 102 patients aged 22-39 years with ultrasound signs of adenomyosis who were going to conceive. The patients were divided into two groups: Group 1 (n = 58) consisted of nulliparous patients with no history of previous intrauterine interventions; Group 2 (n = 58) comprised multiparous women with any of those, such as curettage of the uterine cavity for a non-developing or unwanted pregnancy and separate diagnostic curettage for a reason not related to pregnancy. Using MRI, J-zone maximum thickness was measured at the thickest part. We evaluated the relationship between J-zone thickness and pregnancy outcomes, while estimating J-zone thresholds for subfertility outcomes in the both groups.
Results. The average value of J-zone maximum thickness in Group 2 was significantly higher than that in Group 1 and amounted to 12.1 4.2 mm and 10.3 3.9 mm, respectively (p 0.05). The pregnancy rate in the both groups did not differ significantly and amounted to 43.1% in Group 1 and 38.6% in Group 2 (p 0.05). The frequency of retrochorial hematoma was diagnosed in 13.8% and 22.7% of cases, respectively, and did not differ significantly in the both groups (p 0.05). The frequency of spontaneous miscarriage in Group 1 and Group 2 did not differ, either (6.9% and 6.8%, p 0.05). The J-zone thresholds for unfavorable pregnancy outcomes were determined with a probability of 60% in Group 1 (9.1 mm) and Group 2 (10.0 mm).
Conclusion. J-zone thickness may be used as a prognostic marker of pregnancy outcome in patients with adenomyosis.
A problem of health of the woman and an adaptation to the varying ecological and professional factors
Authors: Novickij A. A. , Dudorenko S. V. , Bobrov L. L. , Obresan A. G.
Published: November 2021

In an article generalizing own scientific data of the authors on influence of the varying factors of the social and ecological environment, joined by a syndrome chronic adaptive strain, on health the woman are represented. In an outcome of studying of mechanisms of development of the given syndrome, the authors allocate a few its links: hypothymie variant of dezadaptation, disintegration of the function of systems hypothalamic- hypophysis-thyreoid of iron and hypothalamic-hypophysis-subrenal- ovarian, depressing glucose and activation lipoid of metabolism process, development lipoid perocsidation and damage of diaphragms of heavily divided cells (immunity of the system, of a gastric-intestinal tract and other).
Tibolone and its metabolits: a pharmacology, tissue's specifics and effects on experimental models of tumoures
Authors: Kloosterboer H. J.
Published: November 2021

Tibolone represents steroid with wear estrogenic, progestagenic and androgenic properties, which can use as alternative usual hormonal replacement therapy (HRT). A series experiments for study influence of tibolone and its metabolits on a tissues in vitro and in vivo was conducted. The tissues selectivity of tibolone was found in a bone, where the estrogenic activity restores of a bones weight and quality the rats bone after ovarioectomy and the absence of estrogenic activity prevents of endometrial proliferation. Tibolone did note stimulate the cellular proliferation in the lines of tumoures crates and reduced a load of a tumour at the tumoures of mammary glands, called DMBA as on a model of preventive maintenance. It was shown that tibolone and each of from three metabolits considerably reduce in average load of the tumour after 10 weeks of treatment. These results show, that metabolits can introduce contribution to final effect of tibolone in the experiments in vivo and that metabolism plays a key role in a problem selective tissues effects of tibolone.
Estrogen replacement treatment with transdermal patches
Authors: Repina M. A. , Zinina T. A.
Published: November 2021

The article provides a comparative analysis of oral and transdermal estrogen replacement use in peri/postmenopausal women.
On the article by M.V. Shvetsov and N.V. Startseva, "Psychotherapy in Women with the Threat of Miscarriage" (Journal of Obstetrics and Women's Diseases, 1998, v. 1).
Authors: Kaplun I. B.
Published: November 2021

This article summarizes the experience with Lowen's body-oriented therapy in 100 pregnant women with the threat of pregnancy failure.
Analisis of marker serum proteins in prenatal diagnosis of chromosomal disorders
Authors: Kareva I. V. , Kascheeva T. K. , Vakharlovsky V. G. , Kuznetzova T. V. , Aylamazian E. K. , Baranov V. S.
Published: November 2021

Comparative retrospective analysis of serum marker proteins (AFP and hHG), ultrasound examinations and fetal karyotypes was carried out in 306 high risk pregnancies of chromosomal anomalies. Peculiarities of pregnansy histories, birth complications and their outcome were considered respektive of maternal serum hHG values registered at 13-21 weeks of gestation.

Statistically significant deviations of maternal serum proteins (MSP) values were registered almost with equal probabilities ih the groups of high risk pregnancies of chromosomal disorders as well as in the women with noncomplicated pregnansy histories (56,7% and 59,3% respectively).

Chromosome abnormalities were registered in 29 out of total 306 fetuses subjected to invasive karyotyping. 11 out 20 women with chromosomally abnormal fetuses revealed substantial deviations of MSP values. All cases of chromosomal abnormalities correlated with maternal age (over 35) and ultrasound markers in the foetuses. Elevated values of hHG in maternal blood correlated with unfavourable pregnansy outcome.
Potentials of echography in diagnosis of postpartum complications
Authors: Timoshenkova S. V. , Sysloparov L. A. , Rindin V. A. , Tatarova N. A.
Published: November 2021

The results of pelvic echography in postpartum period and after Cesarian sections were analyzed. Echography on the 2,4,5 and 7 days of postpartum period as a screening method of the puerperal of risk groups offers an early diagnosis and adequate management of patients with pyo-inflammatory diseases, are therefore required to reduce these severe forms of complications.
Application of Ovestin in gynecologic practice in children and teenagers
Authors: Bogdanova E. A.
Published: November 2021

In this article the suggestions for ovestin implication (estriol creme) in children gynecological practice are considered.
A class of preparations «progestagens»
Authors: Repina M. A.
Published: November 2021

In the lecture there are considered questions of synthesis, classification, dosage, pharmacokynetics, and dynamics, indications and contraindications for application of a class of preparations called progestagens.
Acute abdomen in gynecology of children
Authors: Jaroslavsky V. K.
Published: November 2021

In abstracts there are a considered information about the causes of acute abdomen in gynecology of children. The clinics, diagnostics, tactics of treatment and methods of treatment are considered.
On some fundamental mechanical characteristics of myometrium
Authors: Savitsky G. A. , Savitsky A. G.
Published: November 2021

Each contractile element in muscular wall of uterus, having between itself direct mechanical relationship and spot of fixation, possesses a spontaneous contractile activity, which at isometrical mode of shortenning alike on temporary and power parameters. Functional homogeneity bounds between contractile elements, is ensured as myocites receptors characteristics, so that mechanical characteristics of connective tissue framework miometrium. To extended the optimum sprained contractile element myometrium it is necessary to apply the power 4 times greater, than the capable to develop any contractile element of myometrium during spontaneous or stimulated phasic isometric reduction.
The prospectives for caudal epidural anestesia in gynecology
Authors: Rostomashvili E. T. , Kolomietz U. V. , Ermolaeva N. I.
Published: November 2021

The experience of caudal epidural application anestesia is submitted for operations in gynecologic patients. The hypoosmolal anestethic solution (osmolality 260 Mosm/kgs) is used, prepared on the basis of the solution, concentrated 10 %, lidocaine, 0,9 % sodium chloride solution and distillated water. The caudal epidural anestesia application during operations allowed to ensure reliable protection against a surgical trauma, not rendering adverse influence on systems of breath and blood circulation. The analgetic effect duration made 30,5 hours, at sedative drugs potentiation it was increased even more. Complications of a used technique are not marked. Simplicity and, safety of a technique allow to recommend it to wide practical use.
Features of the central hemodynamics of the pregnant women with insulin-dependent diabetes (IDD) mellitus and gestosis
Authors: Busurukova P. S.
Published: November 2021

Central hemodynamics was tested by rheographyc method by Kubichek at 169 women at term of 27-34 weeks of pregnancy with IDD and gestosis of a mild degree, with gestosis without infringements of a carbohydrate exchange and practically healthy. There are the essential changes of the central hemodynamics are revealed at the mild forms of gestosis: frequency of cardiac reductions, diastolic and average hemodynamics pressure, systemic peripheric resistance were higher, and the parameters of work of heart - stroke output, shock index, volumetric rate of emission and capacity of a left ventricle - are lower, than appropriate parameters of the healthy pregnant women. At a nephropathy-I is shown, that the infringements of a vascular link of a hemodynamics increases at conservation of changes cardiodynamics, having a place at edemas in pregnant women. At pregnant woman with IDD and gestosis an infringement of a hemodynamics deeper, than at pregnant with gestosis without diabetes. These infringements are shown by aggravation of a heart failure and vascular complications, even at the mild forms of late gestosis.
The clinical aspects of a preparation «Divigel»
Authors: Prilepskaya V. N. , Bairamova G. R.
Published: November 2021

In the last years both in our country, and abroad with the purpose of climacteric syndrome treatment, and also for preventive osteoporosis maintenance in heart diseases is used with success a hormonal replacement therapy (HRT) with, estrogens and gestagens. The carried out research has proved, that the Divigel drug has high efficiency and acceptability in climacteric syndrome treatment. Thus the percentage of side-effect reactions at its application is minimal. Besides one of the advantages of a preparation is the transdermal way of introduction, that allows to avoid hormonal metabolic changes in primary passage through a liver and to avoid occurrence of irritation by-effects on the digestive system.
The life and work of academician Gromov Sergei Alekseevitch (to 225-anniversary of birth-date)
Authors: Tzvelev Ju. V.
Published: November 2021

As to continue my 50-year period of work in medicine, I noted the way the medical science is developing in the fatherland. And as I have seen its quick development I could have hardly stay not amazed. For half-century before that we were only students and the followers of our leaders - foreign men, because we didnt have any native leader in any of the medicine field. But now, thanks God...we are equal to their level and can do our way ourselves.

S.A. Gromov (1852)
Effects of two monophasic oral contraceptives containing 150 mcg of desogestrel in combination with 20 or 30 mcg of ethinylestradiol on adolescent girls with oligomenorrhea and ovarian hyperandrogenism
Authors: Nappi K. , Leone F. , Nicotra A. , Fareis M. J. , Carlo C. Dee , Montenmegno J.
Published: November 2021

Adolescent girls in the early years after their first menstruation are characterized by frequent irregular menstrual cycles and absence of ovulation, often associated with clinical signs of hyperandrogenism, including hirsutism and acne. Often in these adolescent girls, both the ovarian structure and endocrine characteristics do not allow to distinguish the disease from polycystic ovarian syndrome (PCOS) observed in adults.
The new approach in the treatment of the sexual transmitted diseases
Authors: Cavlis T. I. , Kirichenko V. F. , Taitz B. M.
Published: November 2021

Syndromic approach has been written in this publication. Syndromic approach is the new approach for diagnostics and treatment of sexual transmitted diseases.
Perimenopause - from contraception to hormone replacement therapy
Authors: Smetnik V. P.
Published: November 2021

Perimenopause is a period of age-related decline in ovarian function, mostly after age 45, including premenopause and one year after menopause or 2 years after the last independent menstruation. Menopause is the last independent menstruation due to the function of the reproductive system. The date of menopause is set retrospectively, that is, after 12 months of no menstruation. Menopause occurs on average around the age of 50.
Correction of vessel-trombocyte infringements hemostasis in peri-and postmenopause with the help of a preparation Flogensyme
Authors: Repina M. A. , Corso Т. М. , Zinina Т. А. , Riskevitch S. I.
Published: November 2021

The authors specify that the method of system ensymetherapy opens new opportunities in regulation of a major link in pathogenesis of heart diseases in elderly - effective and safe normalization of intravascular trombocyte activation and their amplified aggregation function. The purpose of system ensymetherapy does not exclude, and, on the contrary, supplements replacement hormonal therapy, helps to remove by-effects connected to reception of hormonal preparations.
Bemithyl efficiency in complex therapy of chronic fetal hypoxia in gestosis
Authors: Rjabynin G. B. , Smirnov A. V. , Tzvelev U. V. , Zarubina I. V.
Published: November 2021

The results of the carried out clinical approbation of a preparation have shown, that at term pregnancy in complex therapy of chronic fetal hypoxia caused with gestosis, the inclusion of bemithyl is expedient. The reception of a preparation within 5 days in a daily dose of 10 mg/kgs of weight of a body divided into 3 receptions is recommended.
Obstetric and gynecologic clinic from Pavlov's medical university. Place in structure of obstetrical service of the city
Authors: Kucheryavenko A. N. , Novikov B. N.
Published: November 2021

The statistical data on work of obstetric and gynecologic clinic from Pavlov's medical university in comparison with municipals one are submitted. The prospects of development of obstetrical service are given.
In-water labor
Authors: Ailamazyan E. K.
Published: November 2021

The authors of the article share the point of view, that people are mammal creatures and are to fulfil the labor process not in water but on the surface.
The mistakes in diagnostics and treatment of tubal pregnancy with the use of laparoscopy
Authors: Goda I. B. , Bezhenar V. F. , Berlev I. V.
Published: November 2021

In ectopic pregnancy diagnostics there can be objective difficulties in realization of the differential diagnosis with interrupting uterine pregnancy. The author considers the most typical mistakes in diagnostics and treatment of a pathology.
Diagnostic difficulty in a patient with recurrent attacks of acute polyneuropathy: Acute intermittent porphyria
Authors: TEKİN Selma , KARAGÜLMEZ Ahmet Mağrur , ERDOĞAN Çağdaş , DEĞİRMENCİ Eylem , TOKGÜN Onur
Published: November 2021

Acute intermittent porphyria is one of the most common porphyria subtypes. There is a critical need to diagnose porphyria, given its multisystem nature and the poor prognosis associated with incurable cases. Here we present the case of a 27-year-old female patient who had severe abdominal pain and who was operated on due to ileus with tetraparesis that manifested following an operation. The patient had muscle weakness in four limbs and symptoms of sympathetic hyperactivity and electrolyte imbalance. Moreover, neurophysiological studies supported acute axonal polyneuropathy. Owing to the neurological symptoms, electrophysiological studies, metabolic disorders, and the severe abdominal pain noted, porphyria was suspected. Porphobilinogen and ALA levels increased in the 24-hour urine test, and the patient was diagnosed with acute intermittent porphyria. In patients who have unexplained recurrent abdominal pain with additional autonomic dysfunction, neurological and / or psychiatric findings, porphyria, a rare disease, should come to mind.
Brazilian Road Freight Transportation Sector: The Challenge of Sustainability
Authors:   Federal Institute of Acre (IFAC), Management and Business Department, Rio Branco/AC, Brazil, Soliani Rodrigo Duarte
Published: November 2021

The road cargo transportation system has significant representativeness in the Brazilian economic scenario. Companies depend on transportation to receive inputs from their suppliers and take their products to consumers. This modal is also the major consumer of fuel oil products in the transportation sector. Thus, it is necessary to act with a focus on sustainability, considering the economic, social and environmental aspects. From this perspective, this study aims to present aspects of the concept of sustainability in the Brazilian road freight transportation sector, with emphasis on the environmental, social and economic dimensions. A qualitative research approach was used with the literature research technique in order to build the theoretical basis for discussion on the dimensions of sustainability in Brazilian road freight transportation. The results show that the road cargo transportation sector is relevant for the country and seeks to fulfill its social role and be economically viable; requires attention to environmental awareness and eco-efficiency; should make efforts to use alternatives to avoid damage to the environment, applying technologies to reduce noise pollution, GHG emissions; and seek to comply with environmental legislation acting in a sustainable manner.
Secondary attack rate among high-risk contacts of COVID-19 paediatric index cases: a study at the beginning of the pandemic in Pune city of Western Maharashtra, India
Authors: Jagadale Ganesh R. , Tambe Muralidhar P. , Jadhav Yallapa , Borle Pradip S. , Parande Malangori A. , Hatnapure Minal , Salunke Priyanka , Shinde Pradnya , Paunikar Apeksha , Galande Arundhati
Published: November 2021

Background: The COVID-19 was the emerging disease caused by SARS-COV2. Efficient transmission of this disease occurs through droplets and fomites. The susceptibility of children to coronavirus disease-19 (COVID-19) and transmission of COVID-19 from children to others is a relatively unexplored area. The aim of this study was to understand the transmission dynamics of severe acute respiratory syndrome coronavirus 2 in children. Study objectives were to estimate secondary attack rate of COVID-19 from paediatric index case during the early phase of pandemic in Pune city and to identify factors associated with transmission and development of the COVID-19 disease.Methods: This was a retrospective cohort study conducted in the month of June 2020. The sample includes 58 contacts of 11 laboratory confirmed pediatric index cases of COVID-19 from Pune municipal corporation after written informed consent. A confidential telephonic interview of parents was taken by using a prestructured questionnaire which includes socio-demographic data, family background, type of house, development of symptoms, outcome etc.Results: The mean age of primary pediatric case was 12.7±5.1 years. All of them were symptomatic. The SAR estimated was 55.2%. The factors significantly affecting SAR were comorbidity, no. of family members, type of family, overcrowding, no. of rooms, bedroom attached with toilet.Conclusions: The household SAR from paediatric patients is high and is closely associated with family size and other household characteristics. Hence, home quarantine should be advocated in smaller families with appropriate isolation facilities; more emphasis is given to co-morbid individuals.
Milan scoring system in the diagnosis of salivary gland lesions for assessment of risk of malignancy
Authors: Grandhi Bhavana , Rao B Syamsundara , Rao N Mohan , Sunandha G V
Published: November 2021

Salivary gland lesions are one of the most common encounters in clinical practice for the evaluation of which Fine needle aspiration cytology is a well-established technique nowadays. Owing to the heterogenecity and morphological overlap between the various categories of these salivary gland lesions, there was a need for a standardised procedure. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) provides a standardised evidence based reporting system to assess the risk of malignancy and thus helpful for the management of these lesions. We have undertaken this study for evaluation of salivary gland lesions by this newly introduced grading system for predicting the malignant potential of these lesions.

: We have done a prospective study of all the salivary gland lesions received in our department for a period of 3 years from 2016 to 2019. The clinical history, aspiration cytology and histopathological examination was done for all the cases.

: We have received 225 salivary gland lesions for aspiration, but histological follow up was done in only 105 lesions, which were thus included in our study. Case distribution into different categories was done in the following way:ND (5.71%), NN (38.01%), AUS (2.57%), NB (33.34%), SUMP (1.9%), SM (2.85%), and M (15%). Overall, ROM reported were 25%, 5%, 20%, 4.4%, 33.3%, 85.7%, and 97.5%, respectively for each category. Overall, sensitivity was 83.34%, specificity was 98.01%, positive predictive value was 94.87%, and negative predictive value was 91.89%.

MSRSGC is a six category scheme that was recently proposed that separates the salivary gland FNAC into distinct categories, thus increasing the specificity by limiting the number of false negative and false positive cases.
Cystic lymphangioma over the sternum: An extremely rare and atypical localization
Authors: Aloorker Uttara K , Patil Narendra R
Published: November 2021

Cystic lymphangioma is a benign lymphatic system malformation that occurs usually in children. Most common site being cervicofacial region followed by axilla; the cases in the chest wall are very rare. We report a case of male infant with cystic lymphangioma occurring at an unusual site- over the sternum.
Pleomorphic lipoma: A rare entity
Authors: Nayak Goutami Das , Mohanty Shushruta , Mohapatro Meenakshi
Published: November 2021

Pleomorphic lipoma is a rare neoplasm that is considered as a variant of spindle cell lipoma. It predominantly occurs in the dermis or subcutis of the posterior neck, upper back, and shoulders. Pleomorphic lipoma may clinically present as a slow-growing and well-circumscribed subcutaneous mass. Though it is a benign tumour it may contain atypical cells for which it may mimick sarcoma or other malignant soft tissue tumours. So histopathological diagnosis is vital for preventing unnecessary surgery. Here we report a case of a pleomorphic lipoma on upper back in a 55yr old patient.
Retroperitoneal teratoma with malignant somatic transformation: Tumor within a tumor
Authors: Kripalani Mamta , Jagadale Rakhi V , Khochikar Makarand V
Published: November 2021

Extra-gonadal teratomas are rare and occur at various sites with the retroperitoneum being an unusual site. We report a case of an adenocarcinoma arising in a mature retroperitoneal teratoma with bilateral lung metastasis in a young female. Around less than 20 such cases have been reported in literature with the present case being probably second in the Indian scenario and the first to have adenocarcinomatous component matastasize to lungs. We hereby emphasize on the importance of looking for such suspicious areas in a teratoma in order to tailor subsequent management.
El peculado en la legislación penal peruana
Authors: Reátegui Sánchez James
Published: November 2021

En el presente ensayo, el autor realiza un extenso análisis de las características del peculado, considerando los planteamientos doctrinarios, legislativos y jurisprudenciales, tanto nacionales como comparados, desde los aspectos históricos hasta aquellos de naturaleza funcional y práctica. De esta manera, se da cuenta de las implicancias de este acto criminal, a partir de la descomposición de cada uno de sus elementos.
Análisis del comportamiento de la actividad de rayos y sus variables meteorológicas en ciudades de montañosas. Caso Manizales, Colombia
Authors: Del Río-Trujillo Diego Fernando , Younes-Velosa Camilo , Zambrano-Nájera Jeannette
Published: November 2021

El presente artículo muestra el comportamiento diurno y estacional de la actividad de rayos y su relación con las variables meteorológicas que intervienen en la formación de las tormentas, en una ciudad de montaña. Los resultados muestran que Manizales tiene en promedio 69 días tormentosos, es decir, son los días donde al menos un rayo es detectado. Dentro de los resultados, también se puede apreciar que los meses con mayor actividad son marzo y noviembre. El análisis se realizó para los dos periodos lluvioso y seco que se presentan en la zona andina de Colombia. Los resultados muestran que durante los periodos de lluvia la actividad de rayos es más intensa y que obedece principalmente a vientos locales y al desplazamiento de la Zona de Confluencia Intertropical. Dentro del análisis de las variables meteorológicas fue utilizado el ciclo diurno promedio para observar el comportamiento de estas durante los días con actividad de rayos y los que no tuvieron actividad, las variables analizadas fueron presión de superficie, temperatura superficial del aire, temperatura de punto de rocío, razón de mezcla, vientos zonal y meridional.
Análisis del alto flujo vehicular para una vía de acceso a Medellín usando simulación basada en agentes
Authors: Orozco-Rivera Johana , Ceballos Yony , Castillo-Grisales Julian Andrés
Published: November 2021

En Medellín, la vía que atraviesa el parque de Robledo ha jugado un papel importante como ruta de acceso a diferentes barrios del occidente y a municipios de la subregión occidental antioqueña. Diariamente, cientos de vehículos transitan por allí, por lo que esta se identifica como la única vía de acceso, situación por la que en ciertas horas del día se torna lenta. A pesar de que se buscan vías alternas, no se encuentran resultados satisfactorios, ya que la única posibilidad está igual o más congestionada que la primera. En este documento se propone realizar un análisis de la problemática de congestión vial presentada en la vía del parque de Robledo en el sentido oriente-occidente, mediante simulación basada en agentes. Para la realización del modelo de simulación, se caracterizan los individuos por medio de rasgos relevantes, y a su vez se desarrolla una evaluación del comportamiento por mejorar en capacidad vial por ampliación, y la validación respectiva de los resultados obtenidos por medio de esta alternativa. Como resultado se observa que la adecuación de la vía mediante su ampliación facilita y mejora las condiciones de movilidad, aumentando hasta en un 20 % la velocidad de desplazamiento y optimizándose la capacidad vehicular del trayecto hasta el doble en horas pico.
Computational analysis of homogeneous nucleation and droplet growth applied to natural gas separators
Authors: Prieto-Jiménez Natalia , Fuentes José , González-Silva Germán
Published: November 2021

A natural gas droplet is generated at certain thermodynamic conditions through three stages: supersaturation, where the gas has more molecules than it should have in equilibrium, forming “embryos” of liquid phase; nucleation, where embryos form groups of different shapes and sizes of nanometer order; and the droplet growth, where the number of molecules increases until equilibrium is reached. In this paper, the homogeneous nucleation and droplet growth of natural gas applied to gravitational separators operating at high pressure conditions (7MPa) are analyzed. The results showed that at a high pressure, the initial drop size reached was 8.024 nanometers and the final diameter of the drop was 4.18 micrometers.
Using Expert System Application to Diagnose Online Game Addiction in Junior High School Students: Case Study in Five Big City in Indonesia
Authors: Aziz Abd. , Setyawan Bagus Wahyu , Saddhono Kundharu
Published: November 2021

The development of computer technology gradually increases. An artificial intelligence-based system also begins to be developed and used in various fields. One product of artificial intelligence is an expert system, used for psychological field. This study aimed to explain and describe the using of expert system to diagnose online game addiction to Junior High School Students. This is based on online game addiction phenomenon happening to Indonesian student especially in Junior High School. The implementation of this expert system used certainty factor method. Steps for developing this system were divided into four, namely designing expert system or architecture of expert system, representing knowledge, designing database, and testing and implementing the system. The results indicate that this system is divided into two domains, including user and admin. The user domain is provided for users who are willing to do online consultations using system expert application. Meanwhile, the admin domain is provided for an admin to manage each datum and question from the user who conducts an online consultation. From 1000 samples, it is obtained that 69% amongst total samples of Junior High School Student have a low-level addiction to online game, 25% experience medium-level addiction, and 6% are highly addicted.