bluuebunny/crossref_metadata_2025 huggingface dataset:
Differentiation between Call Fleming syndrome and nervous system vasculitis
Authors: Ribeiro Fernanda Cristina Poscai , Rodrigues Everton Lopes
Published: November 2022

IntroductionCall Fleming syndrome is a reversible cerebral vasoconstriction syndrome of idiopathic etiology that causes thunderclap headache. It is a condition with a good prognosis, but clinically and radiologically similar to other diseases, such as nervous system vasculitis.
Objectives To bring clinical, radiological and laboratorial aspects of Call Fleming Syndrome and nervous system vasculitis and provide the differentiation of both.
MethodologyThe research is an integrative review, carried out in June 2022, using the SciElo and Pubmed databases. From the keywords: Call-Fleming syndrome) AND (Diagnosis), (Case report), (Radiology), the clinical, laboratorial and radiological profile of the Call-Fleming Syndrome was traced while the keywords (Nervous System) AND (Vasculitis) AND (Diagnosis), (Case report), (Radiology) were used to CNS vasculitis. Then, from case reports, radiology articles and laboratory analyses, the diseases in question were compared in terms of similarities and differences.
ResultsBoth pathologies are similar from a clinical point of view: they are frequent causes of thunderclap headache, a sudden and severe headache that reaches its maximum intensity within 1 minute. Some patients with Call-Fleming Syndrome may present several neurological deficits, the more frequents in case reports are hemiparesis, hemianopia, and loss of balance. The disease has a limited course that lasts from 1 to 3 months, however, its main complications are hemorrhages and cerebral infarction. The age group affected in the reported cases ranges from 10 to 76 years and there is a slight predominance of cases in women. (To see the complete abstract, please, check out the pdf).
Release of CGRP in vivo from rat dura mater: Influence of capsaicin and topiramate
Authors: Costa Raisa Ferreira , Rosas Emanuela Paz , Oliveira Daniella Araújo de , Valença Marcelo Moraes
Published: November 2022

Introduction
Migraine is a disease that stands out for its high prevalence with changes in the nervous system, abnormal levels of neurotransmitters, neuromodulators, and neuropeptides. The main mechanisms of action of capsaicin are chemical induction through the activation of TRPV1 channels, allowing calcium influx into neurons in the trigeminal ganglion of the dura mater, activating mast cell degranulation, releasing pro-inflammatory (e.g., histamine, oxide nitric) and vasoactive (e.g., CGRP and substance P) substances. For treatment, classes of drugs are used to act on blood vessels and to prevent vasodilation, as well as depolarization of sensory fibers of the dura mater.
Objectives
To better understand sterile inflammation after exposing the dura mater bilaterally, we created an experimental model to study mechanisms of action of topiramate and capsaicin in mast cell degranulation and release of CGRP in a rat skull preparation in vivo using anesthetized animals.
Methods
Thirty-five Wistar rats were used, divided into two groups of chronic topiramate (GTC) treated with 20mg/kg/day, gavage/10 days, and acute topiramate (GTA) in situ in the dura mater (10-3M). The animals were anesthetized and cranial windows between the coronal and lambda sutures in the hemicraniums were performed with a drill to expose the dura mater bilaterally. 10-3M capsaicin was placed on the right side and synthetic interstitial fluid on the left side and exposed to contact for 10 minutes to a small cotton ball soaked with the respective solutions so that there is no leakage of the treatment, and posteriorly kept in the freezer (-20°C) for later quantification of CGRP. The percentage of degranulated mast cells was quantified after removal of the dura mater by staining it with toluidine blue. A commercial enzyme immunoassay quantified the release of CGRP from the cranial dura mater...
(Too see the complet abstract, please, check out the PDF.)
Cephalalgia heterotopica: a case series of lower half face migraine
Authors: Bordini Carlos Alberto , Silva Junior Hilton Mariano da
Published: November 2022

Introduction
Migraine is a common and very disabling neurological disease. It typically causes severe throbbing pain or a pulsing sensation, usually on one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. According to the definition of headache, the pain should be located in the head or in the face above the orbitomeatal line. Beyond this classical view, recent evidence has shown that it could be an arbitrary boundary, and other clinical features can prevail during the diagnosis process. 
Objective
This consecutive case series study aimed to report clinical features, treatment, and outcome of 5 patients with a lower-half facial presentation of migraine. 
Materials and Methods
Case series of our Headache Clinic.  Data disclosure was authorized by the patients through an informed consent form.  
Results
Of the 5 patients, 3 were women and 2 were men. Mean age was 34, 6 (13-56 years). The mean age of symptoms onset was 15,2 (11-29 years).
All patients described a throbbing, moderate to severe pain in the malar area. 
Four patients reported frequent phonophobia and photophobia accompanying pain attacks. One patient reported great relief of pain with rizatriptan and another with sumatriptan. Preventive treatment with pizotifen, propranolol, flunarizine, amitriptyline, divalproex sodium, and pregabalin was useful. All patients underwent extensive dental and otolaryngological evaluation and treatment, which were worthless.  
Conclusion
Migraine orofacial presentation is a diagnostic challenge. Proper recognition of these cases not only prevents unnecessary examination and treatment trials but directly benefits the patients since effective treatment is already available. 
A proper case definition of this rare clinical presentation may provide new insight into our understanding of the migraine mechanisms. 
 
Keywords: Facial pain, Migraine, Lower half-face migraine.
Cephalalgia heterotopica: a case series of extratrigeminal cluster headache
Authors: Bordini Carlos Alberto , Silva Junior Hilton Mariano da
Published: November 2022

Introduction
Cluster headache is a very disabling neurological disorder that usually presents with unilateral severe headache associated with ipsilateral cranial autonomic symptoms.  Even among the typical cases, there is a considerable diagnostic delay and most patients will have seen three general practitioners before being referred to neurology services, some having been to colleagues in dentistry or otorhinolaryngology. The extratrigeminal presentation of this condition poses a great obstacle to a proper diagnostic workup. 
Objective
This consecutive case series study aimed to report clinical features, treatment, and outcome of 3 patients with extratrigeminal Cluster Headache.  
Materials and Methods
Case series of our Headache Clinic.  Data disclosure was authorized by the patients through an informed consent form.  
Results
Two males and one female were evaluated.  The ages were 53, 64, and 71 years. The mean age of symptoms onset was 50, 60, and 66 years, respectively. Two patients described excruciating shoulder pain and one presents severe pain in the malar area. All patients reported prominent autonomic ipsilateral symptoms such as lacrimation, conjunctival injection, nasal symptoms, and restlessness accompanying pain attacks. Preventive treatment with verapamil and occipital nerve block was useful.  
Conclusion
Extratrigeminal cluster presentation is a diagnostic challenge. Proper recognition of these cases prevents unnecessary examination and treatment trials and directly benefits the patients since effective treatment is already available. 
A proper case definition of this rare clinical presentation may provide new insight into our understanding of the cluster headache mechanisms. 
Keywords: Cluster headache, Extratrigeminal headache, Shoulder pain.
Spontaneous bleeding of an arachnoid cyst: a rare cause of thunderclap headache
Authors: Domingues Renan , Ribeiro Saulo Ramos , Mello Ana Lucia de Carvalho , Miranda Carolina Franciely Vitor , Pacheco Evelyn de Paula , Carvalho Joao José Freitas de
Published: November 2022

Introduction
A thunderclap headache is a severe headache that starts suddenly and may be a sign of a condition that can be life threatening.
Objective
To present a case of a rare cause of thunderclap headache. 
Case presentation
A 37-year-old female patient was admitted in the neurological emergence service of a private hospital in the city of São Paulo. She had sudden, explosive, and pulsatile headache, with photophobia and phonophobia. The neurological examination had no focal signs. She had deep vein thrombosis in 2014 in the past and since then she has been irregularly using Warfarin.
She underwent CT and MRI of the skull that showed enlargement of the bilateral retrovermian and retrocerebellar cerebrospinal fluid space, with thin membranes/septations inside, and heterogeneous content, with deposition of hemoglobin degradation products. Such findings are consistent with a retrovermian arachnoid cyst with hemorrhagic content. The INR was 1.
Conservative and symptomatic treatment was started, and control CT was performed on the second day of hospitalization, demonstrating almost complete reabsorption of hematic material.
The patient was discharged after 2 days of hospitalization with complete headache improvement.
Conclusion
Arachnoid cysts are collections of fluid located between the meningeal membranes. They are congenital and are formed due to a valve defect in the arachnoid membranes leading to a collection of cerebrospinal fluid (CSF) in its interior.
Most arachnoid cysts are an incidental finding. About 1 to 2% of the population has an arachnoid cyst and symptoms appear when the cyst increases in size or bleeds. 
Our patient had a are complication of and arachnoid cyst not related with the use of anticoagulant. 
Keywords: 
Thunderclap headache, Arachnoid Cyst Bleeding, Arachnoid Cyst.
Rocky Mountain spotted fever, an underdiagnosed cause of headache
Authors: Ribeiro Fernanda Cristina Poscai
Published: November 2022

IntroductionRocky Mountain spotted fever is a tick-borne rickettsiosis. The main clinical signs and symptoms are fever, severe headache, rashes and myalgia. Endothelium tropism can lead to vasculitis, thrombosis, and hemorrhage. In addition, the disease can generate neurological impairment through meningoencephalitis, characterized by holocranial headache. It is considered difficult to diagnose and underreported because nonspecific signs and it is commonly confused with dengue.
Objectives To analyze the epidemiology of spotted fever in São Paulo (state) between 2010 and 2020.
MethodologyThe work is a descriptive cross-sectional study that statistically analyzes the cases of spotted fever in São Paulo between 2010 and 2020 through data obtained by the Information System of Notifiable Diseases (SINAN). The proportions of spotted fever cases were calculated according to: sex, age group, race/color, infection environment, confirmation criteria and evolution. The correlation coefficient between human development index (HDI) and that of the reporting city and mortality was estimated. The number of inhabitants and HDI were from the latest IBGE (Brazilian Institute of Geography and Statistics) census in 2010.
ResultsThere are 869 cases were confirmed (representing 44% of the country's cases), of which 324 are from the metropolitan region of Campinas. The correlation coefficient between HDI and deaths is 0.06 and the average HDI of the cities is 0.79. (To see the complete abstract, please, check out the PDF).
Effect of melatonin on degranulation of dura mater mast cells in Wistar rats
Authors: Reis Rita Santana dos , Ferreira Maria Rosana de Souza , Costa Raisa Ferreira , Valença Marcelo Moraes
Published: November 2022

Introduction
Migraine is a highly prevalent neurological disorder that affects about 15% of the world's population. Involved in migraine pain, the cranial dura mater is a richly vascularized and innervated membrane, where we also find mast cells, and immune cells that help in the formation of the inflammatory process. As one of the treatments for migraine, we have melatonin, a hormone produced in the pineal gland and with properties such as circadian cycle control and antioxidant action. Capsaicin, a bioactive compound found in peppers and with a pungent and burning effect, also has an action in the painful process and serves as a tool in the study of physiopathogenic processes.
Objectives
To evaluate the degranulation of dura mater mast cells from Wistar rats stimulated in situ with capsaicin and synthetic interstitial fluid (SIF) and previously treated with melatonin.
Methods
Twenty-five male Wistar rats were used, obtained from the Department of Antibiotics - Danti of the Federal University of Pernambuco - UFPE and with use authorized by the Ethics Committee in the Use of Animals - CEUA of UFPE, according to protocol nº 0084/2019. During the adaptation period, the animals were acclimatized under standard laboratory conditions, with water and food ad libitum. After this period, they were separated into two groups: a control group (CG) (n = 12) and a melatonin group (GM) (n = 13), and underwent a daily treatment for 10 days with the intraperitoneal application. The GM received a dosage of 10 mg/kg of the animal weight of melatonin diluted in a saline solution at 0.9% and the GC was treated only with the vehicle. After the treatment, the animals were anesthetized and submitted to an experimental surgery...
(To see the complet abstract, please, check out the PDF.)
"Not otherwise specified headache" in emergency department: an analysis of 149,603 visits to nine Upa's 24h in Fortaleza
Authors: Carvalho João José de , Alves Jamille , Severino Fernanda , Reis Virginia , Deulefeu Flavio
Published: November 2022

Introduction

Headache is one of the most common neurological symptoms and is almost a universal experience that requires medical attention on many occasions. Patients often seek medical advice for headaches in primary or secondary health care systems. In these scenarios, establishing the correct diagnosis of headache and referring further treatment to a specialist is essential. Hundreds of low-complexity Emergency Care Units (called UPAs 24h) were opened throughout the country in the last decade. Working 24/7, many UPA 24 h are one of the preferred places by patients to treat acute headaches.

Objectives

This study aims to evaluate the frequency of the "Not otherwise specified headache diagnoses" in patients who seek UPA's 24-h for headache.

Methods

We evaluated the ED charts of 149,603 visits motivated by headache to nine UPAs 24h in Fortaleza, Ceará, from January 2017 to April 2022. In addition to the demographic data, the care flow chart, the MTS classification, the times of each step of care (from risk classification to discharge or death), and the final diagnosis coded by the attendant physician using the International Classification of Diseases (ICD-10). Data were analyzed using statistical software, and a p <0.05 was considered for significance.

Results

The 149,603 consultations, which represented 3,5% of the total, were made by men and women (72 and 28% respectively) with 38.2 (± 14.6) years of age, on average. Regarding the diagnosis, only 25,121 (16.8%) patients received the diagnosis of migraine, and 4,671 (3.1%) were diagnosed with “other cephalic algic syndromes”. The remaining 119,811 (80.1%) had the not otherwise specified headache discharge diagnosis in their charts.

(To see the complet abstract, please, check out the PDF.)
Intracranial hypertension associated with treatment of acute promyelocytic leukemia with all-trans retinoic acid (ATRA): a case report
Authors: Alvarenga Tarcísio N , Sousa-Santos Patrick Emanuell , Pozzobon Pedro Machry , Santos Itamar Meireles , Baston Ana Beatriz , Teixeira Igor de Lima e
Published: November 2022

Case presentation

Female, 18 years-old, without relevant family history, referred to Neurology by Hematology for headache. 3 years ago, she was diagnosed with Acute Promyelocytic Leukemia (APL) currently on maintenance therapy with All-Trans Retinoic Acid (ATRA). The patient reports that in all previous cycles presented headache with the following characters: one-side temporal location, pulsating quality, moderate intensity, with nausea and vomiting, photophobia and phonophobia, uncertain duration, with simple analgesics response. In the current cycle, she relates continuous pain, severe intensity and unresponsive to medication. On examination, there were no focal neurological findings and on funduscopic examination there was no papilledema. MRI and laboratorial tests were normal. Cerebrospinal fluid (CSF) opening pressure was 35 cmH2O, no other alterations. 15 milliliters of CSF were removed, with a closing pressure of 25 cmH2O. A hypothesis of Intracranial Hypertension associated with use of ATRA was made. Afterwards, there was important improvement of the headache, with residual pain of mild intensity. Therefore, Acetazolamide was started at a dose of 250 milligrams every 12 hours with complete resolution of symptoms.

 

Discussion

Acute myeloid leukemia (AML) comprises a heterogeneous group of aggressive blood cell cancers that arise from clonal expansion of malignant hematopoietic precursor cells in the bone marrow. Acute promyelocytic leukemia (APL) is a biologically and clinically distinct variant of AML. APL is classified as acute promyelocytic leukemia with PML-RARA. The cytogenetic hallmark of APL is a translocation involving RARA, the retinoic acid receptor alpha locus on chromosome 17. Without treatment, APL is the most malignant form of AML, with a median survival of less than one month.

(To see the complete abstract, please, check out the PDF).
Correlation between sensitization and range of motion in children and adolescents with migraine
Authors: Santos Michelle Aparecida Anjos , Pradela Juliana , Silva Nathiely Viana , Dach Fabiola , Bevilaqua-Grossi Débora
Published: November 2022

IntroductionMigraine affects 7.7% of children and adolescents and presents with short duration, bilateral and generally frontotemporal localization, however, the relationship of pain and sensitivity symptoms and their correlations with physical tests as well as range of motion are not well understood in these groups.
ObjectiveCorrelate sensitization including allodynia and pressure pain threshold (PPT) of cervical muscles with neck mobility in children and adolescents with migraine.
MethodsFifty children (CH) and adolescents (AD) diagnosed with migraine by ICHD-III were screened, of both sexes, aged between 6 and 17 years at the tertiary headache outpatient clinic. Allodynia was assessed by the adapted allodynia questionnaire based on the ICHD-III and the sensitivity of the cervical muscles sternocleidomastoid, elevator, suboccipital, trapezius and scalene by the pressure pain threshold (PPT) using a digital algometer DDK-20 Kratos®. The active mobility of the cervical spine (ROM) was evaluated in the movements of flexion, extension, lateral flexion, and rotation by the Flexion Rotation Test (FRT), using the CROM®.
ResultsThe mean age of patients was 11.7 years (SD=3.0), most of them female (n=31/62%), adolescents (n= 28/56%) with a diagnosis of episodic migraine (n=32/64%), of low intensity (2.4; SD=0.6), pulsatile quality, duration in hours (18.0; SD=22.7) and more than half of the sample had no aura (n=32/64%). More than 70% of the sample had some comorbidity associated with the diagnosis of migraine, and neurological diseases, such as epilepsy, were more prevalent in both children (25.2%) and adolescents (26.3%), followed by respiratory diseases in children (20.1%) and psychological conditions in adolescents (19.8%). (To see the complete abstract, please, check out the PDF).
Neurological adverse events after vaccination against sars-cov-2 in the municipality of Parnaíba, Piauí
Authors: Júnior Edmar José Fortes , Freitas Francisco Ricardo Nascimento , Martins Francisco Lukas Rodrigues , Barbosa Ane Kássia de Carvalho , Abreu Thyago Layron Sampaio de , Silva Hildnel Rodrigues Leal , Fé Rodrigo Campelo de Moura
Published: November 2022

Introduction
At the end of 2019, a new disease that would come to be known as COVID-19 emerged in Wuhan, Hubei province, China, caused by a virus called novel coronavirus or SARS-CoV-2. The infection has spread worldwide, causing many deaths, however, at the end of 2020, the first vaccines against this new virus appeared, approved by regulatory bodies as being effective and safe. However, since the beginning of immunization, there has been much speculation within the general population both about the supposed low efficacy and the correlation with serious post-vaccination adverse events (APVE), including deaths. Furthermore, it is highlighted in the literature that neurological manifestations are one of the main sources of AEFI. Objective: Therefore, the objective of this study is post-vaccination adverse events against covid-19 in the municipality of Parnaíba, Piauí.
Objectives
1) Investigate the occurrence of post-vaccination adverse events of a neurological nature of vaccination against Sars-CoV-2 in the municipality of Parnaíba, Piauí.
Methods
This is a cross-sectional, observational, descriptive and epidemiological quantitative study. Data were collected from the Information Sistema de Informação de Eventos Adversos Pós-Vacinação (SI-EAPV) of Secretaria de Estado da Saúde do Piauí, in the period from January 2021 (date of the beginning of vaccination against COVID-19 in Brazil) to September 2021. The study population was concentrated in the municipality of Parnaíba, located in the state of Piauí, Brazil. According to the Instituto Brasileiro de Geografia e Estatística (IBGE), the estimated population for the municipality in question is 153,863 people. The dependent variable is the presence of neurological manifestation as an outcome: yes/no. The other variables analyzed were color/race, sex and the description of the vaccine used.
 
(Too see the complete abstract, please, check out the PDF).
Republicanismo e justiça global em Philip Pettit
Authors: Paulo Neto Alberto
Published: November 2022

A perspectiva republicana da justiça global propõe o conceito de “soberania globalizada” como sendo a ampliação da liberdade como não-dominação ao contexto internacional. A teoria política republicana de Pettit observa que as crises econômicas e políticas da atualidade colocaram os Estados democráticos de direito sob o dilema de atender as exigências de sua população e os ditames das instituições financeiras. As instituições financeiras e bancárias estabeleceram as medidas de investimentos e de cerceamento em relação à política orçamentária dos Estados. Segundo Pettit, a lógica de ação das corporações financeiras se tornou transgressora à soberania e à autonomia dos Estados. O conceito republicano de “soberania globalizada” institui a forma dos princípios regulativos que deve reger as decisões políticas e se estabelece como o impedimento a qualquer arbitrariedade ou interferência de grupo político, financeiro ou de qualquer outra natureza que almeja a imposição da vontade sobre o arbítrio dos cidadãos e sobre a autonomia política dos países. O ideal de “soberania globalizada” possui a capacidade de conduzir ao aperfeiçoamento das relações entre os cidadãos e o Estado porque institui a forma política de contestação e de proteção contra qualquer dependência que o agente político possa ter em relação aos ditames das corporações financeiras e a intromissão de outro Estado na soberania estatal. Além disso, esse ideal de política internacional exige que os Estados atuem de forma cooperativa com os cidadãos de outros Estados que sofram com a extrema pobreza ou estejam em condições degradantes.
NÚMEROS DE CASOS E MORTALIDADE POR LEUCEMIA INFANTOJUVENIL NO BRASIL
Authors: Santos Paula Geovana Reis , Cardoso Camila Kellen de Souza
Published: November 2022

Objetivo: O objetivo desse estudo foi analisar os dados sobre números de casos e mortalidade por leucemia infantojuvenil no Brasil por meio das bases de dados secundárias entre os anos de 2007 e 2017. Métodos: trata-se de um estudo observacional do tipo transversal retrospectivo em bancos de dados secundários de acesso público. Os dados foram coletados dos bancos de dados Globocan (IARC – International Agency for Research on Cancer) e da BasePop (INCA - Instituto Nacional de Câncer José Alencar Gomes da Silva), no período de novembro de 2019 a fevereiro de 2020, considerando os critérios de inclusão: crianças e adolescentes (zero a 19 anos de idade), todas as etnias e ambos os sexos; leucemias linfoides e mieloides, sendo elas agudas e crônicas; dados de casos (números absolutos) e mortalidade em todo o Brasil (incluindo estados, capitais e municípios). Por outro lado, excluiu-se adultos, idosos, gestantes e outros tipos de câncer infantojuvenil. Resultados: o número de casos de leucemia infantojuvenil no Brasil foi maior na faixa etária de 15 a 19 anos, no sexo masculino e etnia como “outros”. Já a mortalidade por leucemia infantojuvenil foi mais expressiva na faixa etária de 15 a 19 anos, no sexo masculino e nas regiões nordeste e sudeste. Conclusão: após análise de oito gráficos, foi observada a necessidade de mais estudos abordando esse tipo de análise, bem como a atualização melhor das bases de dados brasileiras para um melhor estudo e posicionamento.
The Effect Of Gallery Walk Techniques On Students’ English Writing Ability In Report Texts
Authors: Azhary Tambusai Suci Adiany,
Published: November 2022

The objective of this research was to find out the effect of that gallery walk technique on students’ English writing ability in report texts at the tenth grade students of SMA Swasta Baitul Aziz Bandar Klippa. The type of research was quantitative research and it was conducted by using experimental design with two classes, in experimental class consisted of 23 students and control class consisted of 27 students. In technique of collecting data, the researcher conducted pre-test, treatment and post-test by writing test. The data were analyzed by using t-test formula. The result of the data showed that tobserve (6.55) value was higher than the ttable in which tobserve>ttable (6,55>1,67). The finding showed that the hypothesis was accepted. It means that there was a significant effect of gallery walk technique on students’ English writing ability in report texts at SMA Swasta Baitul Aziz Bandar Klippa Academic Year 2021/2022.
Need Analysis of Android E-Module based on Problem Based Learning Integrated of Anti-Bullying
Authors: Noprina Winda , Fitria Handayani Dina , Deswarni Dini
Published: November 2022

Inovasi pembelajaran harus terus dilakukan di tengah kemajuan dunia digital yang begitu pesat. Namun inovasi yang dilakukan harus tepat sehingga dapat mencapai tujuan pembelajaran. Pada pembelajaran teks diskusi masih banyak hambatan dalam mencapai tujuan pembelajarannya. Penulisan teks diskusi yang diarahkan untuk membangkitkan 4C pada siswa yakni keterampilan berpikir kreatif (creative thinking), berpikir kritis dan pemecahan masalah (critical thinking and problem solving), berkomunikasi (communication), dan berkolaborasi (collaboration) belum sepenuhnya tercapai. Diperlukan bahan ajar dan model pembelajaran yang tepat untuk mengatasi permasalahan tersebut. Penelitian ini merupakan penelitian deskriptif kualitatif dengan tujuan akhir mendapatkan hasil analisis kebutuhan dalam mengembangkan e-modul. Aktivitas pengumpulan data dilakukan dengan menganalisis karakteristik siswa, kurikulum, dan materi pembelajaran. Hasil analisis kebutuhan adalah sebagai berikut, (1) Siswa menyukai bahan ajar yang dapat diaplikasikan melalui android, (2) Siswa merasa sangat sangat perlu untuk mengintegrasikan karakter khususnya anti-bullying dalam bahan ajar, (3) KI dan KD pada pembelajaran menulis teks diskusi berada pada tataran kognitif C1, C2, dan C4, dimensi pengetahuan konseptual, dan keterampilan abstrak tingkat konseptual. Dari ketiga analisis tersebut diperoleh kesimpulan perlu dikembangkan e-modul berbasis PBL yang terintegrasi anti-bullying.
„Wir haben das Schlimmste bald hinter uns“
Authors: Shinde Sonia
Published: November 2022

Die Gaspreise sinken, das Konsumklima erholt sich. Es sieht nach Licht aus am Ende des Tunnels – nach dem Winter.
Galeria Karstadt Kaufhof bleibt auf Schrumpfkurs
Authors: Tewes Werner
Published: November 2022

Die Krise von Galeria nimmt kein Ende: Das Unternehmen will sich mit dem zweiten Schutzschirmverfahren in nicht einmal drei Jahren gesundschrumpfen. Eine dritte staatliche Finanzspritze wird es dagegen nicht geben.
„Die Instrumente reichen nicht aus“
Authors: Bender Hanno
Published: November 2022

Das Bundeswirtschaftsministerium plant die 11. Novelle des Gesetzes gegen Wettbewerbsbeschränkungen (GWB). Mit ihr soll das Bundeskartellamt weitreichende Befugnisse erhalten, um ordnend in Märkte einzugreifen, in denen der Wettbewerb gestört ist. Wirtschaftsminister Robert Habeck will ein Kartellrecht mit „Klauen und Zähnen“ schaffen. Die LZ sprach mit dem Düsseldorfer Ökonomen Justus Haucap über das geplante „New Competition Tool“.
Berlins populärste Kauffrau
Authors: Tewes Werner
Published: November 2022

Aus einer Händlerdynastie stammt sie nicht. Im Edeka-Management hat sie auch nie gearbeitet. Stefanie Brehm ist ihren eigenen Weg gegangen – und hat in Berlin quasi aus dem Nichts einen der Top-Kaufmannsbetriebe der genossenschaftlichen Gruppe aufgebaut. Werner Tewes
Edeka kämpft mit Automatisierung
Authors: Bökamp Lena
Published: November 2022

Immer mehr Edeka-Regionen setzen bei der Automatisierung im wichtigen Frischesortiment O+G auf die neuartige Lösung von Cimcorp. Dabei laufen die bereits installierten Pilotanlagen in der Gruppe immer noch nicht reibungslos und auf voller Leistung.
EU macht Händlern Hoffnung auf neue Bezahl-Methoden
Authors: Rode Jörg
Published: November 2022

Die EU-Kommission will den Banken Gebühren für Instant Payments verbieten. Der damit bevorstehende Schub für Echtzeit-Überweisungen sorgt für Beifall der Zahlungs-Experten des Handels: Dank EU dürften in den kommenden Jahren neue und kostengünstige Verfahren für stationäre Läden und Online-Shops entstehen.
Henkel spart Energie
Authors: Rode Jörg
Published: November 2022

Henkel hat durch die Digitalisierung von Produktion und Lieferketten nicht nur Kosten gesenkt und Flexibilität gewonnen, sondern auch den CO₂-Ausstoß deutlich gesenkt. Das erklärte Supply-Chain-Chef Dirk Holbach beim Consumer Goods Forum.
Preisdruck und Warenverfügbarkeit drücken die Stimmung
Authors: Konrad Jörg
Published: November 2022

Seit Monaten ist der Lebensmittelhandel mit den Folgen von Inflation und dem Streit um Konditionen beschäftigt. Aus der Sicht der Verbraucher fällt die Wahrnehmung von Preisanpassungen und Regallücken für einzelne Lebensmittelhändler allerdings sehr unterschiedlich aus.
„Tierwohl steht in Österreichs Landwirtschaft weit oben“
Authors: Hillemeyer Judit
Published: November 2022

Die Gesellschaft Agrarmarkt Austria, kurz AMA, mit Sitz in Wien, hat einen gesetzlichen Auftrag: Information der Konsumenten sowie die Qualitätssicherung der Lebensmittel. Sichtbare Zeichen dafür sind das AMA-Güte- sowie das Bio-Siegel.
Ölz nutzt Öko-Energie
Authors: Hillemeyer Judit
Published: November 2022

Backen ist energieintensiv. Ölz hat frühzeitig in erneuerbare Energien investiert und damit seine Gasabhängigkeit reduziert.
Konzept zur Förderung von aktiv-dynamischem Sitzen durch die gezielte Erzeugung von Diskomfort
Authors: Kampa Sebastian Philipp
Published: November 2022

Das Sitzen ist unumgänglicher Bestandteil des täglichen Lebens und steht in Verdacht, Rückenschmerzen zu verursachen. Zwar können regelmäßige Sitzhaltungswechsel Rückenschmerzen vorbeugen, jedoch fällt es den Menschen schwer, sich gleichzeitig auf die zu verrichtende Arbeit und regelmäßige Sitzhaltungswechsel zu konzentrieren. Innerhalb dieser Arbeit wird ein Konzept für intelligente Sitzsysteme vorgestellt, mit dem das Sitzverhalten mithilfe von taktilen Reizen in der Sitzfläche beeinflusst werden kann. Um die Einflussparameter und Kenngrößen für die Erzeugung von taktilen Reizen zu ermitteln, werden unterschiedliche Varianten mithilfe eines automatisierten Prüfstands an Probanden untersucht. Das vorgestellte Konzept bietet die Möglichkeit einer für den Anwender unbemerkten Sitzhaltungsbeeinflussung, wodurch die Konzentration und Produktivität nicht negativ beeinflusst wird.

Inhaltsverzeichnis

Abkürzungsverzeichnis ............................................................................................. VII

Kurzfassung ............................................................................................................. VIII

Abstract .................................
Assessment and Analysis of Undergraduate Fall Enrollment Trends of The Selected College of Agriculture at the 1890 Land-Grant Universities: 1996 To 2018
Authors: Oluwoye Jacob , Debnath Ratul
Published: November 2022

Background: The 1890 land-grant universities consisted of 19 universities, and these networks of schools and colleges were established under the Second Morrill Act of 1890. These universities aim to strengthen research, extension, and teaching in the food and agricultural sciences and work on funding for scholarships and employment, quality advisement, and a network system with mentors for African American students. Besides food and agricultural sciences,1890 Land-Grant universities create opportunities for African Americans to educate and build careers in agriculture, food, natural resources, and human sciences. Purpose: The purpose of this paper is to assess and analyze the college of agriculture’s undergraduate fall enrollment trends of all the 1890 land-grant universities from 1996 to 2018. Methods: Time series data were collected on undergraduate fall enrollment of the college of agriculture for 18 land-grant universities (one unavailable) and examined the general fall enrollment trend of all universities through the analysis of line chart. Result: The most significant output result of the study is that among the 18 universities, eight universities are highly expected to increase the enrollment number of students, two universities are highly potential for losing students in the future, and others have relatively inconsistent growth rate. Conclusions: The paper concludes that most of the College of Agriculture at the 1890 Land Grant universities have a high potential for enriching its departments in the future. Colleges of Agriculture at the Land Grant Universities were established to improve higher agricultural education for the minorities, especially African Americans. These universities continuously play a vital role in educating African American students. Furthermore, 1890 universities are extremely important to keep the diversities in the professions in the field of agriculture. It can be concluded that particularly the potential declining colleges (West Virginia State University, Tennessee State University, Kentucky State University, South Carolina State University, and Tuskegee University) should be given special attention.
Distribution of Body Mass Index and Random Plasma Glucose as Early Detection of Diabetes Mellitus in Indonesian Students
Authors: Rochmah Nur , Faizi Muhammad , Hisbiyah Yuni , Perwitasari Rayi Kurnia , Kalishah Jihan , Aina Qorri , Nuzula Tyas Maslakhatien
Published: November 2022

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by abnormal elevated blood glucose levels resulting from defects in insulin secretion, insulin action, or both. The prevalence of DM in children and adolescents is increasing worldwide. Until recently, early detection of DM was still not widely done in Indonesia. Therefore, this study aimed to measure BMI and random plasma glucose in Indonesian students. Methods: This descriptive study involving 8th and 9th grade students at Alif Laam Miim Islamic Boarding School Surabaya aged 13 – 18 years old. Height and weight were measured using standard anthropometry. Capillary blood samples were taken on the index or middle finger of the student using a single-use lancet. Statistical analysis was conducted with SPSS using the T-test, Mann-Whitney, and Chi square test. Results: This study included 95 subjects with the mean age of 14.65 ± 1.83 years old. There is no significant difference of BMI (p = 0.63) and random plasma glucose (p = 0.09) between males and females. The distribution of BMI for underweight, healthy weight, overweight, and obesity were 6.32%; 64.21%; 14.74%; 14.74% respectively. None of them had a high range of random plasma glucose. Conclusion: Indonesian students in Surabaya had a healthy weight and a normal range of plasma glucose.
Non-Cirrhotic Hepatocellular Carcinoma with Duodenal Metastasis in Chronic Hepatitis B: Case Report
Authors: Suputra I Gusti Lanang Rama Dwi
Published: November 2022

Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the second leading cause of cancer-related death. The extrahepatic extension is also more common in non-cirrhotic HCC. It most commonly metastases to the regional lymph nodes, bone, and lungs. Metastasis to the small bowel is rare. Further, hematogenous metastasis to the duodenum is incredibly rare. Case: A 67-year-old man was admitted with a recurrence of hematemesis melena, weight loss, weakness, and decreased appetite. There was a history of hepatitis and a family history of liver diseases. Abdominal examination revealed a palpable liver (8 cm below the right costal margin, firm, irregular, and tender). Laboratory studies revealed Hb 5.2 g/dL, SGOT 301.1 u/L, SGPT 244.7 u/L, albumin 2.7 g/dL, HbsAg was reactive with HBV DNA 2.01 x 104 IU/ml. EGD showed that esophageal varices were not visible, the duodenum showed an irregular mass, bleeding on touch, and many blood clots. Abdominal USG revealed hepatomegaly with suspicion of multifocal hepatoma, while a CT scan suggested the appearance of HCC and no local invasion into the small bowel. The result of the fibro scan was severe fibrosis, not cirrhosis. At laparotomy, a hepatic tumor and duodenum were discovered. The histopathological study of the tumor revealed a well-differentiated HCC. The resection of the tumor could not be done. He was given palliative and symptom treatment HCC on non-cirrhotic liver remains an exceptional condition. Conclusion: We report a non-cirrhotic HCC in chronic hepatitis B infection.
A retrospective study of overview of patients visited at Kayachikitsa department’s OPD at TUACTH
Authors: Bhatta Pramod , Shrestha Sirjana
Published: November 2022

Background: Kayachikitsa is one of the most important specialized departments in an Ayurvedic hospital. A number of patients get effective, affordable and safe Ayurvedic services from Out Patient Department (OPD). Objective: the major objective of this study was to find out the treated disease pattern, frequency of patients who got benefits from treatments and services provided in the OPD of Kayachikitsa department. Methods: The study was analytical retrospective in nature where analysis of registered patients’ case record of Kaya Chikitsa OPD during the period of May 15 to November 15 of year 2018 AD. Results: Despite of good number of patients visiting in the OPD of Kayachikitsa department, patients of  different  diseases visited and treated with Ayurvedic medications, due to lack of good publicity and awareness in general population about wide range of treatments available for various diseases in Kayachikitsa department. The follow up cases were also good. Conclusions: The study showed the Kayachikitsa department provided services to various diseases, health services to senior citizens. The follow up cases were also better suggestive of good quality services. Hence improving the services and conducting awareness program can provide better Ayurvedic health services to many needy people.
Cartographie et production spatiale de la société
Authors: FARINELLI Franco
Published: November 2022

La distinction proposée par Henri Lefebvre entre pratique spatiale (espace perçu), représentation de l’espace (espace conçu) et espace de représentation (espace vécu), qui inspire encore la rhétorique académique anglophone dans le domaine des études urbaines et territoriales se court-circuite elle-même. Ce que Lefebvre appelle la "production sociale de l'espace" n'existe pas. Seule existe, à l'opposé, la production spatiale, c'est-à-dire cartographique, de la société.
Observer le Web par le prisme de ses sites
Authors: ALLOING Camille
Published: November 2022

L’auteure historicise cinq périodes du Web dans les pratiques de communication des organisations : le Web des pionniers, le Web des citations, le Web 2.0, le Web social et le Web affectif. Pour chacune, il sélectionne les caractéristiques du site web, qualifie la nature des interactions et usages des internautes, et explicite les stratégies de communication numérique des organisations.
« Raconte tes données », entre euphémisation, standardisation et poétique du chiffre
Authors: RONDOT Camille
Published: November 2022

L’auteure propose une analyse de la mise en récit sur les sites web des nouvelles compétences professionnelles liées à l’écoute des médias sociaux. À partir d’un corpus de sites web d’agences et de consultants en communication numérique, elle analyse les mécanismes d’une rhétorique professionnelle qui implique à la fois une personnification et une euphémisation des stratégies en jeu.
Sémiotique sociale des sites web : genèse d’une méthode
Authors: SAEMMER Alexandra , TRÉHONDART Nolwenn
Published: November 2022

Les auteures présentent une méthodologie d’analyse de sites web issue de la sémiotique pragmatique et qui en déplace le focus du résultat interprétatif vers l’étude de son processus de construction. Cette sémiotique sociale fait débattre collectivement les apprenants sur ce qui compose leurs filtres interprétatifs, afin de mieux les conscientiser et favoriser une posture davantage réflexive.
Analyser la mobilisation contre la LPR sur Twitter : enjeux théoriques et défis méthodologiques
Authors: SIMON Justine
Published: November 2022

L’auteure explique les enjeux à la fois théoriques et méthodologiques des espaces d’expression et de communication que sont devenus les réseaux socionumériques comme Twitter. À partir d’une étude de cas menée sur des contenus discursifs diffusés via ce dispositif, elle en caractérise la diversité des formes de mobilisation en ligne, entre dimension technologique, pratique sociale et pratique sémio-discursive.
Métaphore et analyse de sites web : transformations d’un objet médiatique
Authors: GKOUSKOU Pergia
Published: November 2022

L’auteure étudie la pertinence du concept de métaphore dans l’analyse épistémologique de l’objet « site web », tout en le positionnant dans l’évolution du champ médiatique. En prenant appui sur l’étude des sites web à visée documentaire ou institutionnelle, elle en interroge les mécanismes qui émergent entre concepteurs, usagers et dispositifs techno-sémiotiques dans un contexte évolutif de simulation hypermédiatisée.
Meteotsunami in the United Kingdom: The hidden hazard
Authors: Lewis Clare , Smyth Tim , Williams David , Neumann Jess , Cloke Hannah
Published: November 2022

Abstract. This paper examined the occurrence and seasonality of meteotsunami in the United Kingdom (UK) to present a revised and updated catalogue of events occurring since 1750. Previous case studies have alluded to a summer prevalence and rarity of this hazard in the UK. We have verified and classified 95 events using a developed set of identification criteria. The results have revealed a prominent seasonal pattern of winter events which are related to mid latitude depressions with precipitating convective weather systems. A geographical pattern has also emerged, highlighting three ‘hotspot’ areas at the highest risk from meteotsunami. The evidence reviewed, and new data presented here shows that the hazard posed by meteotsunami has been underestimated in the UK.
UKRAINIAN ETHNO-CULTURAL CENTERS IN ALMATY CITY AND ALMATINSKAYA OBLAST: CURRENT SITUATION AND CHALLENGES
Authors:   Cһ. Valikhanov Institute of history and ethnology, Almaty, Kazakhstan, Kassymova D. , Litvin D. ,   KIMEP University, Almaty, Kazakhstan
Published: November 2022

Ethnic Ukrainian population has been part of the multiethnic society of the Republic of Kazakhstan for a long time. Since late 1980s numerous ethno-cultural centers were created in Kazakhstan, becoming sources of ethno-cultural identity maintenance and means of self-realization for various ethnic groups. This article elucidates the role of the Ukrainian ethno-cultural centers in Almaty city and Almatinskaya oblast that pursue threefold mission: support and maintaining of ethno-cultural identity of Ukrainians, realization of the Doctrine of National Unity of Republic of Kazakhstan and maintaining friendly relations between Republic of Kazakhstan and Ukraine. It also illustrates the challenges that representatives of Ukrainian ethno-cultural community are facing (aging, few contacts with Ukraine, mix of identities). The current state of ethno-cultural centers, as well as potential reasons for their low effectiveness, is examined. Article is based on first-hand information about the day-to-day activity of ethno-cultural centers, including participatory observations and interviews with official representatives of those centers.
SОMЕ PRОBLЕMАTІС АSPЕСTS ОF THЕ СUSTОMS АND LОGІSTІСS SPHЕRЕ ОF THЕ ЕURАSІАN ЕСОNОMІС UNІОN
Authors:   Hасеttеpе Unіvеrsіty, Turкеy, Аnкаrа, Yеrеlі A.B. , Mоvкеbаеwа G. ,   Аl-Fаrаbі Каzакh Nаtіоnаl Unіvеrsіty, Каzакhstаn, Аlmаty, Tоguzbаyеvа A.K. ,   Аl-Fаrаbі Каzакh Nаtіоnаl Unіvеrsіty, Каzакhstаn, Аlmаty
Published: November 2022

Thіs tоpіс rесеіvеd а pоpulаr соlоrіng whеn Каzакhstаn dеmаndеd rеgіstrаtіоn оr оffісіаl rе-rеgіstrаtіоn оf vеhісlеs іmpоrtеd frоm thе соuntrіеs оf thе Сustоms Unіоn аnd thе ЕАЕU. Іn соnnесtіоn wіth thіs сіrсumstаnсе, іndіgnаtіоn оf сіtіzеns wеnt іn mаny сіtіеs, whісh rеquіrеd а sіgnіfісаnt rеthіnкіng оf thе dесіsіоn оf thе gоvеrnmеnt оf thе Rеpublіс оf Каzакhstаn. Sоmе аnаlysts bеgаn tо drаw соnсlusіоns аnd аttrіbutе thіs dесіsіоn оf thе Gоvеrnmеnt оf thе Rеpublіс оf Каzакhstаn tо thе rеgulаtіоn rеgulаtіоn оf thе аdоptеd ЕАЕU lаws, whіlе оthеr аuthоrs rеfеrrіng tо thе mаіn аdоptеd lаws оf thе ЕАЕU stаtеs undеrmіnіng thе аuthоrіty оf stаtеs аnd thе undеvеlоpеd trаnspоrt аnd lоgіstісs systеm. Саr оwnеrs thеmsеlvеs dеmаndеd а spесіfіс dесіsіоn nоt іn fаvоr оf thе mоnоpоly оf thе саr mаrкеt аnd pеrsоnаlіty fасtоrs аnd nоt tо thе dеtrіmеnt оf thе fіnаnсіаl prеdіspоsіtіоn оf сіtіzеns оf thе Rеpublіс оf Каzакhstаn. Nеvеrthеlеss, thе pоіnt іs thе quеstіоn оf hоw muсh thе dесіsіоn wаs mаdе tо rе-rеgіstеr сustоms аnd thе prоfіtаbіlіty оf thе lоgіstісs mаrкеt, whісh undеrmіnеs thе іntеgrіty оf thе аuthоrіty оf thе ЕАЕU. Nаturаlly, аmоng саr оwnеrs thеrе wеrе mіsundеrstаndіngs оf thе bаsіс lаws оf thе ЕАЕU аnd thе pаrtісіpаtіоn оf Каzакhstаn аs thе mаіn mеmbеr оf thе unіоn. Іn thіs rеgаrd, thіs аrtісlе аttеmpts tо rеthіnк thе ЕАЕU lаws іn thе сustоms аnd lоgіstісs sphеrе. Thе spесіfіс tаsк оf аnаlyzіng thе аdоptеd lаws іn thе frаmеwоrк оf thе ЕАЕU іs sеt, whісh rаіsе dоubts аmоng оrdіnаry сіtіzеns аnd lеаd tо сеrtаіn mіsundеrstаndіngs. Bаsеd оn thеsе mаtеrіаls, іn pаrtісulаr fоrеіgn аnаlysts, by mеаns оf а соmpаrаtіvе аnаlysіs аnd mаthеmаtісаl mоdеlіng mеthоds, thе аuthоrs саmе tо thе соnсlusіоn аbоut thе shоrtсоmіngs аnd wеак іmplеmеntаtіоn, оpеrаtіоn аnd fоrсе оf lаws аdоptеd by thе ЕАЕU соuntrіеs. Іn pаrtісulаr, whісh sіdе іs mоrе prоfіtаblе thаn thе іnnоvаtіоn оf оnе sіdе, іn thіs саsе, thе Rеpublіс оf Каzакhstаn аnd hоw justіfіеd аrе thе соnсlusіоns оf thе prеssurе оf thе Russіаn Fеdеrаtіоn оn thе сustоms аnd lоgіstісs struсturе оf thе ЕАЕU.