bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of the social deprivation on the psychosocial difficulties of pediatric cancer survivors: a prospective multicentric study
Authors: Delehaye Fanny , Dejardin Olivier , pellier isabelle , Launay Ludivine , Esvan Maxime , Bodet Damien , Carausu Liana , Lejeune Julien , Millot Frederic , Thomas caroline , Gandemer Virginie , Alves Arnaud , Rod julien
Published: October 2021

Background The posttreatment period is a key part of the management of
pediatric cancer care. At this period, psychosocial effects (scholarly
and psychological difficulties) have been described in pediatric cancer
patients and can be prognostic for the success of social reintegration.
Psychosocial effects and their impact may be related to the household’s
socioeconomic background. The aim of this study was to estimate
psychosocial difficulties during the posttreatment period based on a
social deprivation score. Design This study is based on a prospective
multicentric study database, and focused on the children who had
received psychosocial evaluation during their follow-up after cancer
treatment since 01/01/2013. We retrieved data on their learning and
psychological difficulties. Socioeconomic status of the household was
estimated by a social deprivation score. Results 1003 patients were
analyzed. Learning difficulties at school were noted in 22% of
patients. A greater social deprivation was significantly associated with
learning difficulty (OR=1.09 per unit of the deprivation score). Tumor
relapse, treatment with hematopoietic stem cell transplantation, and
diagnosis of a CNS tumor remained significant risk factors. In the
subgroup analysis of children with CNS tumors, learning difficulties
were increased and associated with greater social deprivation. By
contrast, psychological difficulties were not associated with the
deprivation score. Conclusion There is a link between SE status and
learning difficulties in survivors of childhood cancer. Further
investigations should be carried out to confirm these results for
children with CNS tumors, which is the population of the greatest
concern.
Pharmacokinetics and Bioequivalence of Two Formulations of Eldecalcitol Capsules in healthy Chinese volunteers under fasting and fed conditions and effects of food on pharmacokinetic profiles
Authors: Wu Juan , Fan Yu-ru , Zheng Liang , Liu Yue-yue , Zhang Qian , Zhao Hui , Shen Chen-lin , Hu Wei
Published: October 2021

Aims： The objective of this study was to evaluate the
bioequivalence of two formulations of eldecalcitol (0.75 μg ) under
fasting and fed conditions, and to explore the effect of food on the
pharmacokinetic (PK) properties of eldecalcitol in healthy Chinese
volunteers. Methods： A single-center, open-label, randomized,
three-period, three-sequence, crossover study was performed in 27
healthy Chinese volunteers under fasting conditions. Meanwhile, a
two-way crossover study was performed in 28 healthy volunteers under fed
conditions. Blood samples were collected at scheduled time spots from 0
hour pre dose to 168 hours post dose following administration of 0.75 μg
eldecalcitol. The PK parameters for bioequivalence evaluation calculated
by non-compartment analysis include Cmax, AUC and
AUC. Monitoring of adverse events throughout the
study. Results： The 90% confidence intervals of the
test/reference AUC ratio and C ratio were within the
acceptance criteria. Under the fasting condition, T
values were 3.987 h and 3.489 h in subjects after given the test and
reference formulation respectively. While in the fed study, the Tmax
were 9.006 h and 6.007 h respectively. Therefore, the Tmax was
significantly increased (P < 0.05) under fed conditions. No
severe adverse events occurred during the study and all adverse events
were mild and transient. Conclusion: The generic product of
eldecalcitol was bioequivalent to the reference product in terms of the
rate and extent of absorption under both fasting and fed conditions.
Food intake prolongs the oral absorption of eldecalcitol but does not
significantly influence the system exposure.
The Tetracycline-Controlled Transactivator (Tet-On/Off) System in β-Cells Reduces Insulin Expression and Secretion in Mice
Authors: Jouvet Nathalie , Bouyakdan Khalil , Campbell Scott A. , Baldwin Cindy , Townsend Shannon E. , Gannon Maureen A. , Poitout Vincent , Alquier Thierry , Estall Jennifer L.
Published: October 2021

Controllable genetic manipulation is an indispensable tool in research, greatly advancing our understanding of cell biology and physiology. However in β-cells, transgene silencing, low inducibility, ectopic expression, and off-targets effects are persistent challenges. In this study, we investigated whether an inducible Tetracycline (Tet)-Off system with β-cell–specific mouse insulin promoter (MIP)-itTA–driven expression of tetracycline operon (TetO)-CreJaw/J could circumvent previous issues of specificity and efficacy. Following assessment of tissue-specific gene recombination, β-cell architecture, in vitro and in vivo glucose-stimulated insulin secretion, and whole-body glucose homeostasis, we discovered that expression of any tetracycline-controlled transactivator (e.g., improved itTA, reverse rtTA, or tTA) in β-cells significantly reduced Insulin gene expression and decreased insulin content. This translated into lower pancreatic insulin levels and reduced insulin secretion in mice carrying any tTA transgene, independent of Cre recombinase expression or doxycycline exposure. Our study echoes ongoing challenges faced by fundamental researchers working with β-cells and highlights the need for consistent and comprehensive controls when using the tetracycline-controlled transactivator systems (Tet-On or Tet-Off) for genome editing.
Changes in Supplemental Nutrition Assistance Program Policies and Diabetes Prevalence: Analysis of Behavioral Risk Factor Surveillance System Data From 2004 to 2014
Authors: Khatana Sameed Ahmed M. , Illenberger Nicholas , Werner Rachel M. , Groeneveld Peter W. , Mitra Nandita
Published: October 2021

Objective:

Food insecurity is associated with
diabetes. The Supplemental Nutrition Assistance Program (SNAP) is the largest
US government food assistance program. Whether such programs impact diabetes trends
is unclear. The objective of this study is to evaluate the association between changes
in state-level policies affecting SNAP participation and county-level diabetes
prevalence.

Research Design and Methods:

We evaluated the association between
change in county-level diabetes prevalence and changes in the US Department of
Agriculture SNAP policy index – a measure of adoption of state-level policies
associated with increased SNAP participation (higher value indicating adoption
of more policies associated with increased SNAP participation; range: 1 to 10)
– from 2004 to 2014 using g-computation – a robust causal inference
methodology. The study includes all US counties with diabetes prevalence data
available from the Center for Disease Control’s US Diabetes Surveillance System.

Results:

A total of 3,135 (out of 3,143) US
counties were included. Mean diabetes prevalence increased from 7.3% (SD=1.3)
in 2004 to 9.1% (SD=1.8) in 2014. The mean SNAP policy index increased from 6.4
(SD=0.9) to 8.2 (SD=0.6) in 2014. After accounting for changes in demographic,
economic and healthcare related variables and baseline SNAP policy index, a 1-point
absolute increase in the SNAP policy index between 2004 to 2014 was associated
with 0.050 (95% CI 0.042 to 0.057) percentage point lower diabetes prevalence
per year.

Conclusion:

State policies aimed at increasing SNAP participation
were independently associated with a lower rise in diabetes prevalence between
2004 and 2014.
Cardiovascular Safety and Hemostatic Efficacy of Topical Epinephrine in Children Receiving Zirconia Crowns
Authors: Fazeli Afsoon , Nelson Travis M. , Fazeli Mir Sohail , Lin Yvonne S. , Scott JoAnna
Published: October 2021

Objective:

The primary aim of this study was to determine the cardiovascular safety of topical racemic epinephrine pellets by measuring heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure in children receiving dental care under general anesthesia. The secondary aim was to assess clinical efficacy by measuring time to reach adequate hemostasis.

Methods:

For this pilot study utilizing a split-mouth randomized design, 13 patients requiring prefabricated zirconia crowns on both primary maxillary first molars were recruited. Patients received continuous infusions of propofol and remifentanil with 50–70% inhaled nitrous oxide and oxygen. After randomization and tooth preparation, either saline pellets (control) or racemic epinephrine pellets (experimental) were applied directly to gingival tissue. Vital signs were recorded for 5 minutes. The procedure was repeated on the contralateral side using the alternative (control or experimental) treatment.

Results:

Topical racemic epinephrine compared to saline produced a significantly larger decrease in mean diastolic blood pressure (−11.1% vs −3.9%; P < .01) and mean arterial pressure (−8.1% vs −2.1%; P < .01), although all noted decreases in cardiovascular variables were clinically insignificant. All experimental treatment teeth achieved adequate hemostasis after 2.2 minutes. Only 5 of the 13 control treatment teeth achieved adequate hemostasis during the 5-minute observation period (1.6 vs 4.2 minutes; P = .01).

Conclusion:

Overall, we conclude that use of topical racemic epinephrine pellets did not result in adverse cardiovascular effects and hemostasis was reached more quickly and predictably compared to saline pellets.
Reducing scatter in bent angle by a laser shock peening pretreatment
Authors: Valentino Tobias , Stephen Andreas , Radel Tim
Published: October 2021

Laser shock peening is a surface treatment technology, which modifies the residual stress state of metal parts. When forming thin sheet metal parts with thicknesses ≤1 mm, locally varying residual stress states are, according to the literature, the main reason for the scatter in the bent angle. Forming processes, such as bending, are often used to manufacture thin sheet metal. Thin sheets are formed in quantities of several hundreds of millions per year. Even scrap rates that are in the ppm range, caused by the scatter in the bent angle, lead to considerable manufacturing costs. To ensure a robust forming process, it is hypothesized that the laser shock peening process can reproducibly change the residual stress state in thin sheet metal parts in such a way that scatter in the bent angle can substantially be reduced. Annealed and 1 mm thick sheet metal made of X5CrNi18-10 were processed with a nanosecond pulsed fiber laser. The influence of laser peening without coating (LPwC) on the bent angle was investigated using bottom bending with a nominal bending angle of 90°. It was revealed that the standard deviation of the bent angle, i.e., the scatter, is reduced by a factor of 2 from ±0.14° down to ±0.07° compared to the initial sheet state. Hence, the possibility to use LPwC as a pretreatment to decrease the scatter in the bent angle for thin sheets is demonstrated.
Wetland meadows of carex acutiformis as a source of bioelectricity of agglomeration atmospheric air pollution and environmental safety of the practices
Authors:   Lviv Polytechnic National University, Rusyn Iryna , Dyachok Vasyl ,   Lviv Polytechnic National University
Published: October 2021

The article presents the assessment of bioelectroproductivity of wetland sedge ecosystems of Carex acutiformis in situ. It was found that it is possible to obtain a bioelectric potential at the level of 864.2-1114.8 mV, depending on external conditions using a pair of electrodes graphite/zinc-galvanized steel and graphite/aluminum. The increase in soil moisture had a positive effect on bioelectric potential parameters. Widespread in Polissya biotopes of sedge have prospects as sources of green plant-microbial energy.
PENGARUH MEDIA PEMBELAJARAN ATRAKTIF ROPIBEL TERHADAP HASIL BELAJAR KOGNITIF PADA MATA PELAJARAN IPS SISWA KELAS IV SDN SINGAPADU KECAMATAN CURUG KOTA SERANG
Authors: Evitasari Aris Ika , Wijaya Sastra , Ilannur Nadia
Published: October 2021

Penelitian ini bertujuan untuk mengetahui pengaruh media pembelajaran atraktif ROPIBEL terhadap hasil belajar kognitif siswa kelas IV SDN Singapadu kecamatan curug kota serang. Jenis penelitian yang digunakan yaitu Pre-Experimental Design dengan bentuk desain one-group pretest posttest design. Populasinya adalah seluruh siswa kelas IV di SDN Singapadu Kecamatan Curug Kota Serang. Peneliti mengambil sampel kelas IV berjumlah 37 orang. Teknik pengambilan sampel memakai sampling jenuh. Teknik pengumpulan data menggunakan tes, angket, dan dokumentasi. Berdasarkan perbandingan hasil pretest dan postest yaitu kemampuan pretest pada siswa dengan rata-rata hasil belajar 39,45 yaitu hanya 3 dari 37 siswa yang berhasil mencapai nilai KKM sedangkan kemampuan postest pada siswa dengan rata-rata hasil belajar 71,89 yaitu sebanyak 34 dari 37 siswa telah berhasil mencapai nilai KKM sehingga mendapatkan nilai presentase 91,8 %. Teknik analisis data menggunakan uji “t". Hasil dari penelitian ini adalah sebagai berikut: hasil pengujian uji “t” terhadap hasil belajar pretest dan posttest diperoleh thitung = -12.108 sedangkan ttabel dengan df 72 pada taraf signifikan yaitu 0,000. Dengan demikian nilai signifikasi 0.000 < 0.05 yang berarti kerja (H1) dalam penelitian ini diterima, yaitu terdapat pengaruh media pembelajaran atraktif ROPIBEL terhadap hasil belajar kognitif pada mata pelajaran IPS siswa di SDN Singapadu Kecamatan Curug Kota Serang.
Yapılarda Atık Yönetimi: Bir Eğitim Yapısı Üzerinden Geri Dönüşüm Önerileri ve Karbon Salımının Engellenmesi
Authors: KARA Feride Çiğdem , TUNA KAYILI Merve
Published: October 2021

Enerji ve kaynak kullanımında büyük miktarda payı olan yapılara yaşam döngüsü boyunca yüksek hızda kaynak girdisi sağlanmakta ve hizmet ömrünün dolduğu yıkım sonrası evrede ise yapı bileşenlerinin geri kazanılmasına yönelik atık yönetimi etkin bir şekilde planlanmadığında enerji ve kaynak girdisi, ekolojik ve ekonomik kayıplara neden olmaktadır. Özellikle günümüzde kentsel dönüşüme uğrayan yapıların artması bu sorunu daha da öne çıkarmaktadır. Bu bağlamda, yapıya giren enerji ve kaynakların korunması ve geri dönüşümüne yönelik, Karabük’te yıkımı gerçekleştirilen bir eğitim yapısı üzerinden atık yönetiminin incelendiği çalışmada, yapılan literatür taraması sonucunda atık sahalarına gönderilen büyük miktardaki tuğla ve seramik atıklarının geri dönüşümüne yönelik öneriler belirlenmiştir. Sunulan bu geri dönüşüm önerileri sonucunda doğaya salımı engellenebilecek gömülü karbon miktarı tespit edilmiştir. Tuğla için 220 ton 601 kgCO2 eq, seramik için ise 8 ton 41 kg CO2 eq’nin doğaya salımının engellenebileceği tespit edilen yıkıntı atıklarının öneriler dahilinde sektöre kazandırılmasının, enerji ve kaynak korunumu açısından önemi belirtilmiştir.
Effect of Feeding Rate on Survival, Zootechnical Performance of Tilapia Oreochromis niloticus (Linnaeus, 1758) Brazil Strain Larvae Fed on 17-α-methyltestosterone Treated Feed
Authors: Ouattara Issa Nahoua , Zea Bi Ue Claver , Berte Siaka , Kamagate Bakagnan
Published: October 2021

This study was conducted to evaluate the feeding levels on survival, growth performance and feed utilization in the Brazil strain of Nile tilapia Oreochromis niloticus. Four (4) batches of larvae with mean initial weight 0.012 ± 0.005 g and mean initial total length 9 ± 0.003 mm were formed in triplicate, three per feeding rate. The rationing rates according to fry biomass applied in this trial were: batch 1: 50, 40, 30 and 25%, batch 2: 40, 30, 25 and 20%, batch 3: 30, 25, 20 and 18% and batch 4: 25, 20, 18 and 15% of biomass. The different feeding rates were tested during the 1st, 2nd, 3rd and 4th week of larval rearing respectively. The fish were all fed a commercial feed (48% protein) distributed manually at a frequency of 5 meals per day. After 28 days of rearing, the results show that apart from the survival rate, the other parameters such as final average weight, daily growth and food consumption index were affected by the different rationing rates tested. The larvae of batch 2 rationed at 40, 30, 25 and 20 % of their biomass during the 1st, 2nd, 3rd and 4th week of rearing respectively recorded significantly higher growth parameters (MWF: 1.092±0.027 g and DG: 0.038±0.000 g) and a more interesting food converion ratio (0.88 ) than the other batches of fry. From this study, it is concluded that an optimal feeding rate of 40, 30, 25 and 20% of the larval biomass during the 1st, 2nd, 3rd and 4th week of rearing, respectively, should be applied in order to avoid either wastage or underfeeding of the subjects during hormone treatment with 17 α-methyltestosterone.
Physico-chemical Factors an Phytoplankton as Indicators of the Water Quality in Two Periurbans Lakes of a Natural Protected Area in Mexico City
Authors: Latournerié-Cervera J. R. , Estrada-Ortega A. R. , Escobar-Álvarez A. K. , Quino-Trejo A. J. , Barrera-Pastrana R. G. , Nacif-Osorio Y.
Published: October 2021

The protected natural area (ANP), Ejidos de Xochimilco and San Gregorio Atlapulco (SGA), is a priority area of ecological conservation in Mexico City (CDMX), that still have remnants of the ancient lake system of the Valley of Mexico watershed that have been modified for decades due to the impact of human activities and that threaten their continuity, despite been declared as a RAMSAR site and historical and cultural heritage of CDMX. Given the above, the present study aimed to compare the spatial-temporal variability of physical-chemical factors and phytoplankton as indicators of anthropogenic impact to diagnose the current state of this locality and propose possible alternatives for sustainable management in the study area. The research design considered comparing the area of channels and lagoons of the SGA wetland in two contrasting climatic seasons: dry and rainy. Eleven sampling stations were delimited: three in the channels area and eight in the lagoons, during the months of March and July. Nine physical-chemical variables were measured: temperature, pH, total solids, conductivity, dissolved oxygen, as well as the concentrations of ammonium, nitrites, nitrates, and soluble phosphorus in surface and bottom samples from each sampling station. The statistical design took into account a factorial design of fixed effects (epochs - locations and strata), with Tukey's "post hoc" test to delimit subsets and various multivariate analysis techniques. Phytoplankton samples were taken in both localities, which were identified down to the genus level, evaluating the relative frequency of the various taxa, as well as their association through the saprobity and diversity indexes. The water quality variables indicated that both the area of channels and the lagoons of the wetland are sites with hypereutrophic characteristics, but the wetland due to its semi-isolation is an area that presents on average levels of nitrates 2.4 times lower than in the channel zone, nitrite concentrations are almost imperceptible, and ammonia is within tolerable limits for the existing biota. It also presents space-time homogeneity in its physical-chemical dynamics, in contrast to the area of channels. The composition of species indicating saprobity also differed between both sites, denoting a lesser impact on the wetland area, so it is suggested to use this site for reintroduction activities of species removed from the channel area and preserve the remaining biota in the lake system.
Shea Shells and Press-Cake as New Sources of Bioactive Phenolic Compounds: GC MS Profile and in vitro Antioxidant Activity
Authors: Kouakou A. B. , Doué G. G. , Mégnanou R.-M. , Djoman A. E. S.
Published: October 2021

Shea nuts shells and press cake are shea butter processing byproducts. Their content in phenolic bioactive compounds and their antioxidant capacity were studied. The total phenolic and flavonoid contents ranged between 16.962-21.395 mg GAE/100g DM and 0.243-1.83 mg QE/100g DM, for press-cake and shells, respectively. Antioxidant capacity values assessed by EC50 using DPPH, ABTS and FRAP methods were in the range of 0.398-0.235 mg/mL, 0.623-0.465 mg/mL and 0.137-0.154 mg/mL for shea press-cake and shells, respectively. Shea shells recorded the highest total phenolic and flavonoid compounds positively correlated with DPPH and ABTS radical scavenging. Catechins, arbutin and gallic acid were the most abundant phenolic compound identified by GC-MS chromatography with 10.4; 2.1 and 0.8 g/100 g in shea shells and 2.2; 2.6 and 2.6 g/100 g in press-cake. Based on this phenolic composition shea nuts shells and press cake could be of great importance in cosmetic and pharmaceutical industries, and also contribute to preventing metabolic and cardiovascular diseases.
Morphological Characterization of Twenty One Sweet Pepper (Capsicum annuum L.) Genotypes Collected from Native and Alien Sources
Authors: Ferdousi Jannatul , Zakaria Mohammad , Hoque Md. Azizul , Saha Satya Ranjan , Ivy Nasrin Akter , Hossain Md. Iqbal
Published: October 2021

Sweet pepper is one of the most important nutritious vegetable and its demand is increasing day by day in Bangladesh indicating need to characterize and assess morphological variability for varietal improvement programme. Twenty-one sweet pepper genotypes from native and alien sources were characterized for twenty-six morphological traits using vegetative and reproductive appearances at Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh from October 2018 to March 2019. Marked variation was exhibited among twenty-six qualitative traits (26) studied. Twenty-two (22) characters showed undeniable variation among the genotypes. The presence of higher percentage (61.90%) of light purple color at node were observed indicated high amount of anthocyanin content. Leaf shape is used as genotypes identifier at vegetative stage and herein three types of leaves were found with dark green color (76.19%) that is highly correlates with yield. In case of flower, same level of stigma exertion (61.90%) with 100% white color corolla indicates higher number of fruit sett were exhibited. Entire genotypes exerted one or more exclusive characters especially fruit shape and color in Bangladesh perspective which could be used as an important breeding tools. Fruit color was observed in various categories at intermediate and mature stage as for instance yellow, green, purple, orange, red etc. in addition higher percentage of blocky fruit shape (38.09%) were observed and these are the consumer fascinating attributes of sweet pepper. However, selection of genotypes with desirable morphological trait can be used for their exploitation of future breeding programme.
Preliminary Study on the Solanum nigrum L. (Solanaceae) Complex in the Democratic Republic of the Congo
Authors: Kapesa Blaise Bikandu , Sosef Marc , Janssens Steven , Le  Péchon Timothée , Luyeye Félicien Lukoki
Published: October 2021

Black nightshade, or the Solanum nigrum complex, includes a number of species that botanists consider problematic due to their morphological resemblance and the high rate of hybridization. As part of the revision of the family Solanaceae for the Flora central Africa,we realized a molecular study of the Solanum nigrum complex in the western part of the Democratic Republic of Congo. A total of 21 samples of this complex were collected and identified using the recent revision by [11]. The DNA of each specimen was extracted and then amplified by PCR for 4 molecular markers: the two nuclear regions waxy and ITS, and the two chloroplastics markers trnL-F and trnH-psbA. Additional sequences of specimens reliably identified were obtained from GenBank. The combined molecular data set allowed for the identification of two distinct groups. The first we conclude that in the western part of D.R. Congo, two species of the Solanum nigrum complex occur, both showing high morphological variability, while the true Solanum nigrum is absent from that region. The two species are Solanum americanum Mill. and Solanum scabrum Mill. The results confirm the taxonomic decisions of [11]. The generally low resolution in the analyses did not allow to visualize a geographical signal in the variation.
Effect of Job Satisfaction, Quality of Work Life, and Self Efficacy on Employee Work Productivity Case Study on PT. Bank Woori Saudara Indonesia Tbk
Authors: Sitohang Adisa Putra , Budiono Nur Aktif
Published: October 2021

This study aims to analyze the effect of job satisfaction, quality of work life, and self-efficacy on employee work productivity (Case Study at PT Bank Woori Saudara Indonesia Tbk, Kebon Jeruk Sub-Branch). The population of this study was employees of PT Bank Woori Saudara Indonesia 1906 Sub-Branch of Kebon Jeruk as many as 57 employees, with a total sample of the entire population. The data analysis method used Structural Equation Model-Partial Least Square (SEM-PLS). The results of the study found that job satisfaction has a positive and significant effect on employee work productivity, quality of work life has a positive and significant effect on employee productivity, and self-efficacy has a positive and significant effect on employee productivity. It is suggested to the management of PT Bank Woori Saudara Indonesia 1906 Sub-Branch Kebon Jeruk to review the salary policy given to employees. What can be done is to apply merit pay, which is a compensation system based on employee performance.
Challenges of Milton Friedman’s Contributions: A Perspective of Behavioral Economics
Authors: Zhu Di
Published: October 2021

This paper reviewed Milton Friedman's major contributions and critiqued his theories from a perspective of behavioral economics. Overall, behavioral economics can be a significant supplement to the traditional Friedman's theories to better predict economic events. More specifically, in terms of money supply, behavioral economics found that emotions can distort the assumption of the quantity theory of money and it may also affect economic output through its big role in decision making. As for the permanent income hypothesis, it can better explain the effect of income on consumption from the psychological aspect such as low confidence. His major point of a free market for economic and political freedom can be challenged by Nudge concept from behavioral economics. The government can help people to achieve their goals without damaging their autonomy. In addition, behavioral economics explores more and better reasons for the common phenomena of irrational behaviors against the traditional assumption that people are always rational.
Using A Feed Forward Neural Network Algorithm to Predict Prices of Multiple Cryptocurrencies
Authors: Charandabi Sina E. , Kamyar Kamyar
Published: October 2021

This paper initially presents a nontechnical overview of cryptocurrency, its history, and the technicalities of its usage as a means of exchange. Bitcoin’s working methodology and mathematical baseline is further presented in more depth. For the remaining majority of the paper, recent cryptocurrency price data of Bitcoin, Ethereum, Tether, Dogecoin, and Binance coin was used to train a machine learning model of Feed Forward Neural Networks to predict future prices for each of the datasets. Further and in conclusion, the results are discussed, and the efficiency and accuracy of these models are evaluated.
The Role of Intangibles in the Economic Recovery Post-COVID-19 Pandemic
Authors: Best Rhonda A.
Published: October 2021

The strategic use of intangibles can create unlimited jobs globally. Intangibles are lucrative non-physical assets that every business enjoys but very few utilise effectively. By 2007, early value management studies had proven that businesses with exponential growth had achieved those record performances after shifting their organising models. Today, there is new evidence to support further growth while addressing the societal issue of unemployment. Unemployment in this instance goes beyond the definition used in economics and includes facilitating the ease of an employee’s transition from education to job or from job to job. Creating new jobs is especially important for countries facing tremendous development challenges, exacerbated by the COVID-19 pandemic. According to the International Labour Organization, the world’s job loss due to the pandemic in 2020 was equivalent to 255 million full-time jobs. At the same time, corporations globally have been taking a deeper look at governance practices and are closely examining the impact that commercial strategies have on the environment and society. In addition, the future of work is taking shape as hybrid work from home options are being explored for some roles. While the political and ethical implications of addressing global unemployment cannot be oversimplified, in theory, there can be open accessibility to jobs globally. Today’s availability of education, the relative ease of international trade of services and technological advancement make this possible. This paper shares qualitative research that proposes the role of intangibles in solving unemployment, so a research university might consider furthering this vital work in intangibles.
Exploring Major Factors Affecting Virtual Team Performance
Authors: Topaloglu Murat , Anac Ahmet Serhat
Published: October 2021

Increasing global operations of companies and advances in communication technologies in the last two decades have led companies to create virtual team, in which employees work more productively and cost-effectively from different locations. This situation required virtual team leaders to have a different perspective and management approach than the leaders who manage teams in the usual offices. Performance management is one of the vital tasks of virtual team leaders and is a multidimensional research topic for researchers interested in virtual team management. Knowing the determinants of performance will be useful in quality decision-making, problem-solving, and many other managerial processes. This research aims to explore major factors affecting virtual team performance by using a systematic literature review methodology that includes more than one hundred scientific articles. Findings of this study suggest that these factors are leadership, communication, collaboration, cohesion, commitment, conflict, interpersonal relations, knowledge sharing, feedback, trust, diversity, recognition, and empowerment.
Impact of Leverage and Firm Size on Earnings Persistence with Managerial Ownership as Moderating Variables
Authors: Nurdiniah Dade , Oktapriana Chita , Meita Iren , Yanti Milla Damay
Published: October 2021

This study aims to examine and analyze the effect of leverage and firm size on earnings persistence with managerial ownership as a moderating variable. The population in this study is manufacturing companies listed on the Indonesia Stock Exchange in 2016-2019. The sample selection method used purposive sampling criteria, while the data analysis methods used in this study were multiple regression analysis and moderated regression analysis. Before analysing the data, first perform the classical assumption test, after the data is declared to meet the test criteria, then a hypothesis test is carried out consisting of multiple regression analysis, coefficient of determination test (R-squares), simultaneous significance test (F-test), significance test partial test (t-test) and moderated regression analysis (MRA). The results showed that leverage had a positive effect on earnings persistence, and firm size had no effect on earnings persistence, while managerial ownership was unable to moderate the effect of leverage and firm size on earnings persistence.
Feeding Plate of an Eight-day-old Patient Having Veau Type III Cleft Lip and Palate
Authors: Ghiya Komal
Published: October 2021

Congenital Cleft lip and palate is a craniofacial defect which results into difficulty in feeding because of the communication between the oral and nasal cavities. Feeding plate restores the gap between the oral and nasal cavities and helps in feeding and reduces the chances of airway problems, regurgitations. This clinical report describes a design and method of fabricating a feeding plate in an 8-day old neonate with a cleft lip and palate.
Fallacy of Covid-19 Vaccine Coverage: Discovering Vaccine Hesitancy and Compliance in Private Dental Practitioners and Hospital-based Dentists to Improve Immunization Levels in Pakistan
Authors: Abbas Beenish , Abbas Sana , Rafique Aisha , Aslam Sana
Published: October 2021

Objective: To evaluate Covid-19 vaccine compliance amongst the general private practicing dentists’ population in comparison to tertiary hospital-based dentists in Pakistan post second wave of mass spread of the Covid-19 infection.

Methodology: Multi-centered study conducted after taking ethical research committee approval. Total 300 participants enrolled via paper-based questionnaire. Participants included the general dentists and tertiary care dental hospital-based dentists. Exclusion criteria implied participants of pilot study, participants that were already vaccinated and those unwilling to participate in the study.

Results: 32% of general dentists in Pakistan agreed to immunization if the Covid-19 vaccine is available in Pakistan (p<0.001). General private practicing dentists were also less likely to pay for the vaccination (p<0.001), less confident for a locally manufactured vaccine (p<0.001) as compared to hospital-based dentists.

Conclusion: This study concluded that the general dentists’ population in Pakistan is still skeptical of Covid-19 vaccination and this attitude in-fact poses as a pandemic within pandemic.
Effect of Problem Based Learning Model on Salt Hydrolysis Lessons about the Students Learning Outcomes
Authors: Sukmadani Debby Maulina , Suryelita Suryelita
Published: October 2021

Presentation on the topic of Salt Hydrolysis can be started from a real problem, using the Problem Based Learning (PBL) model. The PBL model should be able to increase students curiosity to get concepts independently. The purpose of this study was to determine the effect of PBL model on salt hydrolysis lessons about the students learning outcomes in SMAN 1 Ranah Pesisir. This research is quasi experiment with non-equivalent groups post-test only design. Data are normal and homogeneous, as of hypothesis testing uses t-test is done at alpha 0.05, obtained tcount 5,2 and ttable 2,67. The result showed that the learning outcomes on salt hydrolysis lessons between classes using PBL model are higher than conventional model in SMAN 1 Ranah Pesisir.
Pengembangan Permainan Scrabble Kimia Sebagai Media Pembelajaran Materi Reaksi Reduksi dan Oksidasi Kelas X SMA atau MA
Authors: Silaban Agnes Basa Prolina , Bayharti Bayharti
Published: October 2021

Scrabble chemistry game as a learning media is one of the alternative media in doing practice questions to strengthen students concepts in the reduction and oxidation reaction material. The purpose of this study was to develop a chemical scrabble game media as a learning medium on reduction and oxidation reaction material. Type of research is Research and Development (R and D) research with 4-D model, namely the stages of define, design, develop and disseminate. This research is limited to the develop stage by conducting a validity test. Data was collected using a validation questionnaire for UNP Chemistry lecturers and chemistry teachers at SMAN 12 Padang. The data analysis technique used the Aiken V formula. The results of the validity test were 0.84 with valid and it was concluded that the chemical scrabble game developed was valid.
Pengembangan Modul Hidrolisis Garam Berbasis Guided Discovery Learning Untuk Peserta Didik Kelas XI SMA atau MA
Authors: Artika Puti Ika , Bayharti Bayharti
Published: October 2021

This research aims to develop and reveal the validity category of salt hydrolysis module based on guided discovery learning. The type of this research is a Research and Development (R and D). This research used Plomp model which consists of preliminary research, prototype, and assessment phases stage. This research is limited to the prototype stage that is prototype II. This module was validated by three lecturers from Chemistry Department FMIPA UNP and two chemistry teachers from SMAN 1 2X11 Kayutanam. The results of the validity test showed that the eligibility of module content has a category valid (V=0.87), linguistic component has a validity category moderate (V=0.8), serving component has a category valid (V=0.89), and graphic component has a category valid (V=0.85). It can be concluded that the module developed has a category valid with average V of 0.85.
Validitas Permainan Ular Tangga Kimia Sebagai Media Pembelajaran Pada Materi Asam Basa Kelas XI SMA atau MA
Authors: Lubis Amalia Putri , Iswendi Iswendi
Published: October 2021

The chemical ladder snake game is one of the variations in learning media in doing practice questions. This type of research is Research and Development (R and D) using the 4-D model which includes the stages of define, design, develop, and disseminate. The research is limited to the develop part of the validity test. The instrument used was a validity questionnaire given to two UNP chemistry lecturers and two chemistry teachers at SMA N 3 Padang. Data collection techniques were analysed using Aiken V formula. Data analysis showed that the level validity of the chemical ladder snake was 0,75, so it can be concluded that the chemical ladder snake developed was valid as a learning media for the acid-base material of class XI SMA or MA.
Keterampilan Berpikir Tingkat Tinggi Siswa Dalam Pembelajaran Model Inkuiri Terbimbing Materi Sistem Koloid: Sebuah Studi Literatur
Authors: Nasution Rizki Anggi Suhairah , Fitriza Zonalia
Published: October 2021

The purpose of this study was to describe students higher-order thinking skills in the guided inquiry learning model of the colloid system material. This research is library research using semi-systematic literature review type. The nature of this research is descriptive analysis. The data collection method in this research is the documentation method with the Miles and Huberman data analysis method. The experimental procedure used follows the following stages: 1) Designing a review, 2) Conducting a review, 3) Analysis, 4) Writing a review. The results of this study showed that students high-order thinking skills in guided inquiry model learning colloid system material can be seen in the exploration, concept formation, application, and closing stages.
Validitas dan Praktikalitas E-modul Sifat Koligatif Larutan Berbasis Guided Discovery Learning untuk Kelas XII SMA
Authors: Sari Monita , Yermadesi Yerimadesi
Published: October 2021

Guided discovery learning based E-module is a teaching material in electronic to support independent learning that follow the stages of guided discovery learning model. The development research was conducted to develop and analyse the validity and practicality of this e-module on colligative properties of solution material for class XII high school chemistry learning. The type of research is educational design research using the Plomp development model consisting of (1) preliminary research, (2) prototyping stage, (3) assessment phase. The e-module was validated by eight validators who are four UNP chemistry lecturers and four chemistry teachers using an instrument in the form of validity questionnaire, while the practicality test was carried out at SMA N 8 Padang by 27 students and three teachers with an instrument in the form of a practicality questionnaire. The questionnaire analysis was performed using the Content Validity Ratio (CVR) for content validation and Aiken V formula for construct validation and practicality. From the results, the data indicate that the solution based colligative properties e-module based on guided discovery learning for chemistry learning in class XII senior high school has valid and practical values.
Urban Biophysical Quality Modelling Based On Remote Sensing Data In Semarang, Indonesia
Authors: Hidayati Iswari Nur , Kusumawardani Karunia Pasya , Ayudyanti A. G. , Prabaswara R. R.
Published: October 2021

Cities are centres of economic growth with fascinating dynamics, including persistent urbanisation that encroaches adjacent arable lands to build urban physical features and sustain services offered by urban ecosystems. Even though industrial revolution, economic dynamics, and environmental changes affect spatial feasibility for housing, complex urban growth is always followed by the development of environmentally friendly cities. However, with such quality having multiple facets, it is necessary to assess and map liveable areas from a more comprehensive and objective perspective. This study aimed to assess, map and identify the biophysical quality of an urban environment using a straightforward technique that allows rapid assessment for early detection of changes in the quality. It proposed a multi-index approach termed the urban biophysical environmental quality (UBEQ) based on spectral characteristic of remote sensing data for residential areas calculated using various data derived from remote sensing. Statistical analyses were performed to test data reliability and normality. Further, many indices were analysed, then employed as indicators in UBEQ modelling and tested with sensitivity and factor analysis to obtain the best remote sensing index in the study area. Based on PCA Results, it was found that the built-up land index and vegetation index mainly contributed to the UBEQ index. The generated model had 86.5% accuracy. Also, the study area, Semarang City, had varying UBEQ index values, from high to low levels.
Coastal Erosion And Tourism: The Case Of The Distribution Of Tourist Accommodations And Their Daily Rates
Authors: De Paula Davis P. , Lima Jailson C. , Barros Eduardo L. , Santos Jader de O.
Published: October 2021

Beaches are key territories for tourist development but at risk of impacts of climate change—specifically with the consequent intensification of coastal erosion. This study examines the effects of coastal erosion on the distribution of lodging facilities and the value of daily rates practiced on the beaches of Tabuba and Cumbuco on the northeast coast of Brazil. The methodology comprises collecting information on the means of accommodation (distribution and daily rate), quantifying coastline variation and measuring the field to validate data. A total of 13.9 km of coastline were analyzed; erosion tendency was observed in 26.8% of the coast (9.0% erosion, 14.4% intense erosion, and 3.4% severe erosion). With the highest erosion rates, Tabuba's Beach has a low density in accommodation distribution and daily rates practiced in tourism. Cumbuco's Beach, conversely, has a lower risk of erosion, and the means of accommodation are concentrated. Coastal erosion has affected tourism development in Caucaia, influencing the choice of tourism accommodation entrepreneurs. the results indicate that there is a clear concentration of tourist accommodations in areas without notorious problems with coastal erosion, influencing in the distribution of tourist facilities and their daily rates. So, there is a direct connection does exist between local tourism system income and the beaches with problems with coastal erosion.
Microplastic Abundance In Volga River: Results Of A Pilot Study In Summer 2020
Authors: Lisina Anastasia A. , Platonov Maxim M. , Lomakov Oleg I. , Sazonov Alexey A. , Shishova Tatiana V. , Berkovich Anna K. , Frolova Natalia L.
Published: October 2021

In order to analyze the problem of microplastics pollution a comprehensive environmental survey was conducted along the entire Volga river in summer of 2020. The analysis of 34 water samples allowed us to determine the average concentration of microplastic (MP) in the surface water layer of the Volga river which accounted for 0.90 items/m3 (0.21 mg/m3). MP particles were found in all samples taken. The concentrations ranged from 0.16 to 4.10 items/m3 (from 0.04 mg/m3 to 1.29 mg/m3). The maximum MP concentrations were recorded in large cities downstream of the sewage treatment plants. For Tver, Nizhny Novgorod, Kazan and Volgograd they reached 3.77, 1.91,4.10 and 1.34 items/m3 respectively. The key role of large settlements as sources of MP in the Volga water was revealed. The minimum MP concentrations were recorded upstream of the large cities showing relatively stable levels of 0.25 items/m3 (0.05 mg/m3). The lowest MP content (0.16 items/m3) was revealed in the downstream area of the Cheboksary reservoir near Cheboksary. The results of weighing MP particles showed that their average concentration in the Volga water is 0.21 mg/m3. In each of the investigated samples particles of three determined fractions - fragments, fibers and films - were found, however, their ratio was not constant. On average, the proportion of fragments and films in the Volga water was 41% and 37% respectively and share of fibers accounted for 22%.
Cloud technologies in the management of pedagogical higher education institutions
Authors: Odarchenko Veronica , Akimova Olena , Kuznetsova Oksana , Lytvyn Valentyna , Karpliuk Svitlana
Published: October 2021

The aim of the study is to systematize relevant information on the use of cloud technologies in the management of pedagogical higher education institutions. In the process of studying, general scientific methods of knowledge, which include analysis, synthesis, comparison, were used. Also, the survey results are used to assess the effectiveness of the application of different technologies and their use to manage the university. According to the results of the study, we can conclude that before the pandemic, the situation in the field of cloud computing was quite different. Only some of the world's best universities were implementing cloud technology in their management processes. Today, almost every higher education institution in the world fully or partially implements cloud technology to provide distance education. The main technological products are offers from Google and Microsoft. They are mainly used to store educational information and organize communications within the educational institution.  The main problems of using cloud technology have been identified, including the load on the IT staff, the problem of licensing and integration with other cloud services.