bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of fatty acid amides with ethanolamine and glycine on nociceptive reactions and gait parameters in rats in normal and experimental peripheral mononeuropathy
Authors: Doronkina A. S. , Mikhalchuk A. L. , Goubkin S. V. , Molchanova A. Yu. , Bogdan V. G.
Published: November 2022

The effects of fatty acid amides ethanolamine and glycine on gait patterns and nociceptive reactions was investigated after injections of these fatty acid derivatives in healthy rats and in rats with experimental peripheral neuropathy. It has been proven that palmitoylethanolamide and the stearoylethanolamide are more effective at relieving neuropathic pain and restoring gait parameters than glycine palmitamide.
Impact of adipose-derived allogeneic mesenchymal stem cell transplantation on nociceptive reactions and gait parameters in rats with experimental peripheral neuropathy
Authors: Yerofeyeva A.-M. V. , Molchanova A. Yu.
Published: November 2022

Peripheral neuropathy is associated with chronic debilitating pain and is difficult to treat. In this regard, the development of cell therapy of neuropathic pain using adipose-derived mesenchymal stem cells (MSCs) seems to be relevant.

The work was devoted to study the impact of adipose-derived allogeneic MSC transplantation on nociceptive reactions in response to mechanical and thermal stimuli and gait parameters in rats with sciatic nerve injury.

It is found that a single local injection of MSCs at a dose of 1·106 cells/kg eliminates axotomy-induced mechanical and thermal hyperalgesia on the 14th day after transplantation, contributes to the recovery of the sciatic functional index and the dynamic gait parameters on the 7th day after transplantation, and prevents the development of gait disturbances in the long-term period.
Theoretical foundations of rendering state support to аgroindustrial complex organizations
Authors: Sayanava I. G.
Published: November 2022

The article presents the results of studies of the mechanism for providing state support to agroindustrial complex organizations, including the directions of financing investment projects. Definitions of the terms “subsidies for the payment of interest (part of interest) for the use of loans”, “budget transfers to reimburse part of the capital costs of investment projects”, and a flowchart for improving the mechanisms of state support for the agroindustrial complex of the Republic of Belarus (classification of state support measures) are given.
The mechanism of marketing support of national subjects of the vegetable market
Authors: Kireyenka N. V. , Arnatovich M. A.
Published: November 2022

A mechanism for marketing support of national subjects of the vegetable market has been developed, which includes a set of regulatory, institutional, marketing and infrastructural conditions to ensure economic relations between market operators. A set of measures to unite producers and processors of vegetables, as well as organizations of trade, transport, logistics, warehousing, packaging at the interstate, national, regional and local levels is substantiated. It is proposed to create a public association “National Vegetable Growers” as a non-profit organization, whose activities will be aimed at providing information and consulting, marketing, representative and educational services.
ANALISIS TINGKAT PENERAPAN TEKNOLOGI DI PT TEGAL SHIPYARD UTAMA, CILACAP
Authors: Erika Kusumaning Ayu  , Kukuh Eko Prihantoko  , Faik Kurohman
Published: November 2022

PT Tegal Shipyard Utama cabang Cilacap adalah salah satu dari tiga perusahaan dock kapal di Pelabuhan Perikanan Samudera (PPS) Cilacap. Perusahaan ini memiliki 3 (tiga) unit jalur slipway dock dan 1 (satu) unit mesin penarik. Sehingga dalam operasionalisasi jalur slipway dock digunakan secara bergantian menggunakan satu unit mesin penarik yang tersedia. Tingkat teknologi yang digunakan oleh suatu perusahaan akan mempengaruhi kinerja perusahaan. Tingkat teknologi dapat diidentifikasi berdasarkan 4 (empat) komponen yaitu technoware, humanware, orgaware dan infoware. Penelitian ini bertujuan untuk menganalisis tahapan proses docking kapal dan menganalisis tingkat penerapan teknologi pada PT Tegal Shipyard Utama cabang Cilacap. Metode penelitian bersifat deskriptif kuantitatif. Penelitian dilakukan dengan studi pustaka, observasi lapangan, dokumentasi dan wawancara dengan responden berjumlah 22 (dua puluh dua) orang yang merupakan tenaga kerja di lokasi penelitian. Data dianalisis secara deskriptif dan model teknometrik. Hasil penelitian menunjukkan bahwa proses docking di lokasi penelitian terdiri dari 4 (empat) tahapan yaitu proses pelayanan dan administrasi, proses penaikan kapal ke dock, proses perawatan kapal dan proses penurunan kapal dari dock. Hasil analisis tingkat penerapan teknologi di lokasi penelitian termasuk pada kategori semi modern dengan nilai TCC sebesar 0,58.

Kata kunci: Cilacap, dock kapal, SWOT, teknometrik
Lymphedema secondary to bartonellosis as a differential diagnosis of breast cancer
Authors: Fonseca Ana Carolina Moreira Mello da , Mello Bruno Licy Gomes de , Falcão Pedro Cavalcante , Oliveira Luiz Carlos Navarro de , Silveira Henrique de Carvalho , Oliveira Luiz Carlos Navarro de , Bacchi Calos Eduardo , Vieira René Aloisio da Costa
Published: November 2022

In the presence of unilateral axillary lymphadenopathy associated with a breast radiological finding, breast cancer should constitute the main differential diagnosis. This fact is intensified when there is associated lymphedema. We present a case of a patient in these conditions, for whom breast cancer was not confirmed, and a subsequent evaluation showed that it was cat-scratch disease. This report constitutes the second case of association between lymphedema and bartollenosis.
Analysis of misconceptions of senior high school students on biodiversity materials, interactions, and their role in nature
Authors: Ilhamdi Mohammad Liwa , Rahmani Aulia Vina , Syazali Muhamad
Published: November 2022

Forming the student's right and correct concept in Biology science is necessary. Lack of understanding of concepts in students can lead to a discrepancy of concepts called misconceptions. This study aims to identify the profile of students' misconceptions in grade tenth on material biodiversity, interactions, and their roles in nature. The results showed that the average conception of students was more significant than those who experienced misconceptions. The average concept is 50.00%, while the average who experiences misconceptions is 29.41%, and 20.59% of students do not answer. If it is categorized in the assessment category, the percentage of misconceptions is in low category.
The use of banana peel as feed to increase growth of earthworms (Lumbricus rubellus)
Authors: Merta I Wayan , Raksun Ahmad
Published: November 2022

Research on using banana peels as feed to increase the growth of Lumbricus rubellus has been carried out. This study aims to determine: (1) the effect of different doses of banana peel pulp on feed on the growth of earthworms (Lumbricus rubellus), (2) the best dose of banana peel pulp to increase the growth of earthworms. This research is a one-factor study. The research was carried out with five levels of treatment and five replications. The doses of banana peel pulp are 0 ml, 250 ml, 500 ml, 750 ml, and 1000 ml. The parameters of the growth of earthworms measured were the addition of the number of individuals and the addition of the weight of the earthworm population. The research data were analyzed by analysis of variance. The research results show that: (1) the difference in the dose of banana peel pulp significantly affected the increase in the number of individuals and the weight of the earthworm population; (2) the addition of 1000 ml of banana peel pulp resulted in the highest number of individuals and the heaviest population weight compared to other treatment doses.
Analysis of students difficulties in mathematics problem-solving ability on number pattern material
Authors: Aisy Nur Mahsarah Rahadatul , Mulyono  , Walid
Published: November 2022

This research aims to analyze and describe students' difficulties in solving mathematical problem-solving abilities on number pattern material. The research method is qualitative research, with the research subjects being grade eight students in one of the schools in the city of Semarang in the academic year 2022/2023. The research instrument was in the form of a mathematical problem-solving ability test and interviews. The mathematical problem-solving ability test indicator uses the indicators proposed by NCTM, with the stages of problem-solving according to Polya. The results showed that students with the concept difficulty type could only understand the problem. The student with the principal difficulty type could carry out the strategy planning stage. Finally, the students with the conceptual difficulty type have been able to implement the stage of planning strategies in solving mathematical problems.
Antioxidant potential of gotu kola leaf extract (Centella asiatica (L.) Urban) as an alternative to antihyperglycemic herbal drinks
Authors: Damayanti Ida Ayu Manik , Antari Ni Wayan Sukma , Megayanti Sri Dewi
Published: November 2022

This study aims to determine the antihyperglycemic potential of Gotu kola leaf extract (Centella asiatica (L.) Urban as an alternative herbal drink in diabetic male white mice. This study was divided into four stages: extracting Gotu kola leaves using 96% ethanol as solvent, phytochemical screening, and testing antihyperglycemic activity. Male white mice were made diabetic by alloxan-induced. Mice were divided into five groups consisting of negative control (Aquadest), positive control (Glibenclamide 13 mg/Kg BW), dose 1 (200 mg Gotu kola extract/kg BW), dose 2 (400 mg Gotu kola extract/kg BW), dose 2 (400 mg Gotu kola extract/kg BW), 3 (600 mg Gotu kola extract/kg BW). The results of phytochemical screening showed that the Gotu kola leaf extract was positive for flavonoids and tannins. The analysis results on the Gotu kola leaf extract showed an IC50 value of 80.58 ppm, including strong antioxidant activity. The results of the antihyperglycemic activity test showed that diabetic male white mice were found to have decreased blood sugar levels on days 14 and 21 by respectively 24.3% and 41.6%; 25.4% and 42.3%; 37.8% and 55.3% after administration of Gotu kola leaf extract at P1, P2, and P3.
Development of android-based learning media applications on elements periodic system topics
Authors: Pradila Anisa , Azra Fajriah
Published: November 2022

This study aims to develop android-based learning media applications and determine the level of validity. This research was designed using the Plomp development model, which consists of 3 stages: the preliminary research stage, the development stage or prototyping, and the assessment stage. In this study, the authors limit the research carried out to the development stage or prototype, which produces prototype III. The development of this android-based application is expected to assist teachers in overcoming obstacles in making learning media and can be used as one of the learning media that can help students in learning, especially on the material of the periodic system of elements. Nine validators carried out the validation test of the learning media application: six content experts (Padang State University lecturers and teachers of SMAN 12 Padang) and three media experts (Lecturer of Engineering Padang State University). The data obtained from the validator was then analyzed using Aiken's V. The product validation test results had an index of 0.877 from content experts and 0.955 from media experts in the valid category. Thus, based on the validation test results, the Android-based learning media application on the developed periodic system material is valid.
Validity of guided inquiry-based chemical equilibrium e-module integrated with the Al-Quran for Madrasyah Aliyah
Authors: Habiba Haura , Iryani Iryani
Published: November 2022

This study aims to determine the validity of the guided inquiry-based chemical equilibrium e-module integrated with Al-Quran for class XI Madrasyah Aliyah. The type of research is developmental research (Educational Design Research) using the Plomp development model, which consists of a preliminary research stage, a prototype stage, and a field test. The research instrument used was a validation questionnaire comprised of a content validation questionnaire and a media validation questionnaire. The content validation questionnaire assessment was carried out by material expert validators consisting of Padang State University Chemistry Lecturers and MAN 2 Padang Teachers. The media validation questionnaire assessment was carried out by media expert validators consisting of Padang State University Chemistry and Informatics Engineering Lecturers. Based on the results of processing the media and content validation questionnaire data using the Aiken V formula, the average value of content validation is 0.88 in the valid category, and the media validation average value is 0.91 in the valid category.
Analysis of independence and creative thinking skills of students through assignment
Authors: Kusmiyati Kusmiyati
Published: November 2022

This study aims to describe students' independence and creative thinking skills through assignments. The subjects of this research are Biology Education students who take the Nutrition Science elective course as many as 20 people. Independence and creative thinking data were collected using an instrument with a Likert scale. The collected data were analyzed qualitatively into five categories. The results of the independence analysis showed as many as 16 students (80%) in the very good category and 4 students (20%) in the good category. The results of the creative thinking analysis showed as many as 13 students (65%) in the very good category and 7 students (35%) in the good category. It can be concluded that most of the students completing lecture assignments have independence and creative thinking skills in the very good category. The achievement of independence on the indicators of not depending on others, self-confidence, self-initiative, and self-control, each student varied from fairly good, good, and very good categories. Meanwhile, the achievement of independence for the indicators of discipline and responsibility varies in the good and very good categories. (c) The achievement of all indicators of students' creative thinking skills varies in the very good and good categories. The very good category was mostly achieved by students on the indicators of flexible and original thinking skills. In contrast, students mostly achieved the good category on the indicators of evaluation thinking skills.
Effectiveness of e-module based on guided discovery learning on learning outcomes of high school students
Authors: Luthfiani Alysa , Yerimadesi Yerimadesi
Published: November 2022

This study aims to analyze the effectiveness of e-module colligative properties of solutions based on guided discovery learning in improving high school student learning outcomes. The research was conducted on class XII students in a public high school space (MAN 1 Padang) with 36 students. The type of research used is quasi-experimental. The research design was a randomized control-group pretest-posttest design, and data analysis used a t-test. The sample was taken by a simple random sampling technique. The level of effectiveness of the e-module is analyzed from the results of the n-gain value. It obtained an n-gain value of 0.71 in the high category. In conclusion, guided discovery learning based on the chemistry e-module effectively improves student learning outcomes with high criteria. Keywords: Effectiveness, E-Module, Guided Discovery Learning, Learning Outcomes.
Effect of the addition of inhibitors of kirinyuh leaf (Chromolaena Odorata) in methanol extract on corrosion rate of ASTM 36 steel
Authors: Widyawati Fauzi , Hidayat Syamsul , Bahtiar Syamsul , Musbihin Musbihin
Published: November 2022

Kirinyuh leaves (Chromolaena Odorata) contain alkaloids, saponins, flavonoids, phenols, and tannins with the potential as a natural inhibitor that can be used to inhibit the rate of corrosion. Kirinyuh leaf extract inhibitors were added at various concentrations of 100 ppm, 200 ppm, 300 ppm, 400 ppm, and 500 ppm, which were sprayed onto the sample surface before being soaked for seven days. Calculation of the corrosion rate using the method of weight loss (weight loss). The results showed that kirinyuh leaf extract effectively inhibited the corrosion rate. The smallest corrosion rate value was found in the sample with the addition of 400 ppm inhibitor concentration, which was 2.053 ppm. Meanwhile, an efficiency inhibitor was also found in the same concentration of inhibitor that is equal to 87%.
Bacteriological quality test of air in the classrooms of Darur Abror Foundation School West Lombok Regency in 2022
Authors: Nurhidayatullah Nurhidayatullah , Azwaruddin Azwaruddin , Mimhalina Liza
Published: November 2022

This study aims to determine the air quality in the classroom. The study showed the quality of air bacteria in the classrooms at the Darur Abror Foundation School (Sudak Gardens Hamlet, Terong Tawah Village, Labuapi District, West Nusa Tenggara, Indonesia) exceeded the predetermined limit on the number of germs in the room. According to Minister of Health Regulation No. 1405/MENKES/SKXI/2002, the germ number is 200-500 CFU/m3. The number of bacteria in the classroom is 2,699 CFU/m3. The most abundant characteristic according to the size of the bacteria is pinpoint. The shape of bacteria based on the number is circular, and the color of most bacteria is white.
Quality Red Spinach Ice Cream With Albedo Peel Extract Paste Stabilizer
Authors: Pranata Franciscus Sinung
Published: November 2022

Ice cream is a semi-solid dairy product and is consumed as a snack or dessert. This study used natural ingredients in the form of red spinach as a natural dye because of the anthocyanin content and albedo of pomelo peel as a source of pectin. This study was conducted to determine the physical, chemical and microbiological quality of ice cream with the addition of red spinach extract and pomelo peel albedo extract paste, to determine the best concentration of red spinach extract to produce ice cream containing antioxidants and to determine the effect of adding orange peel albedo extract paste. Bali as a stabilizer for the quality of red spinach extract ice cream. This study was conducted using a completely randomized design (CRD) with four comparisons of red spinach extract and pomelo peel albedo extract, namely 0:0 (K), 4:0,5 (A), 6:1 (B), and 8:1,5 (C). The results of the research on ice cream products obtained overrun 71.67%-100%, melting rate 883 seconds-1024 seconds, fat content 8.72%-12.80%, protein content 4.40%-9.31%, total solids 23.75%-26.67%, total sugar 20.73%-21.67% and antioxidant content 2.98%-75.07%. The results of ALT and the presence of Salmonella were in accordance with SNI at the National Standardization Agency (1995). The best quality ice cream in this study was ice cream treatment C with the addition of red spinach extract and albedo paste extract of pomelo peel at 8:1.5%.
Analysis of the impact of nurses' actions on health education of hypertensive and diabetic patients in a basic unit in Pernambuco
Authors: Silva Emerson José de Souza , Lima Isabel Chryslayne Rocha de , Santos Kayo Emanuel Silva dos , Araujo Ãndria Beatriz Félix de , Carneiro Caroline Dantas Albuquerque , Silva Eraldo Rodrigues da , Lira Éverton Barbosa de , Leão Josinete da Silva Lira , Soares Rayana Mirelle de Lima , Lima Rayane Karolly Honório , Silva Isabele Ferraz da , Araujo Suenia Maria de Souza Silva , Oliveira Janice Vasconcelos de , Lima Maria Stella Amorim de
Published: November 2022

Health education is the foundation for the non-pharmacological control of hypertension and diabetes and proposes reflection on the importance of co-responsibility for self-care. This study aimed to analyze the impact of nurses' actions on health education of hypertensive and diabetic patients in a Basic Health Unit. This was a descriptive, interventionist study with a quantitative approach. Most of the participants were female, married, with incomplete elementary school. The most prevalent risk factors were: family history, stress and sedentary lifestyle. There was an increase in understanding about the concepts of diseases, lifestyle habits, importance of non-pharmacological treatment, recognition and prevention of complications, frequency and quality of food and frequency and duration of physical activity. The findings reinforced the importance of the role of nurses as a health educator and as a promoter of changes in life habits, contributing to the control of diseases.
O POTENCIAL HUMANITÁRIO DA OBRA DE PAULO FREIRE
Authors: Cardoso João Casqueira , Silva Jaciana Castro , Ramos Tainara
Published: November 2022

A obra de Paulo Freire representa uma abordagem inovadora da pedagogia, numa
perspetiva profundamente humanista. Ilustra essa perspetiva a sua vontade de dar voz aos
alunos, de colocar o educador e o educando num plano de igualdade, e de fazer partir o
ensino das condições concretas do meio de vida. A forma de ver a humanidade, e os
princípios seguidos por Freire, tocam aqui a perspetiva humanitária. Para além disso, a
obra colossal que Freire tem uma vocação universal e a sua abordagem uma vocação para
aplicar-se à escala global. Para extrair o potencial humanitário da obra de Freire, é preciso
de definir o seu contexto global, e em particular na sua vertente internacional. A análise
implica igualmente um vai e vem entre os princípios humanitários e os princípios contidos
na obra de Freire. Desta obra, que continuou para além do seu autor na encarnação diária
do trabalho da educação, é possível perspectivar uma visão para a renovação dos
princípios, éticos e políticos, próprios da prática humanitária.
Serviços públicos como vetores do bem-estar e reestruturação econômica
Authors: Kerstenetzky Celia Lessa , Apolinario Valdenia , Garcez Cristiane , Gaitán Flávio Alfredo , Lastres Helena Maria Martins , Bastos Carlos Pinkusfeld , Cassiolato José Eduardo
Published: November 2022

Documento executivo formulado a partir das exposições e debate do webinário inaugural da Série "Propostas de Política para um novo Brasil", realizada em conjunto entre o Centro Internacional Celso Furtado de Políticas para o Desenvolvimento e a RedeSist - Rede de Pesquisa em Arranjos e Sistemas Produtivos e Inovativos Locais, sediada no Instituto de Economia da Universidade Federal do Rio de Janeiro, em 26 de julho de 2022. Disponível em: https://youtu.be/Qx44JEYcbrA.
Aproximaciones sobre el concepto de “República” en Francisco Bilbao, 1844-1865
Authors: Sáez Muñoz Francisco
Published: November 2022

El presente artículo tiene como principal objetivo explicar el ideal republicano del intelectual chileno Francisco Bilbao (1823-1865). Para la reconstrucción de su teoría se examinó el contexto de la época y de la producción de diversos escritos de su autoría publicados entre 1844 y 1864, como “Sociabilidad Chilena”, El Gobierno de la Libertad, La América en Peligro, El Evangelio Americano, como también artículos divulgados en la Revista del Nuevo Mundo. A partir del análisis de estos opúsculos, se postula que su ideario maduró y evolucionó afín a su contexto intelectual —entre el radicalismo y el socialismo romántico— y continental. Al respecto, se expone que su idea republicana se basó en los tópicos de “regeneración popular” y “gobierno directo del pueblo”, representando una oposición al ideario liberal hegemónico de la centuria.
Arturo Alessandri Palma: balance historiográfico en torno a su construcción heroica (Chile, siglo XX)
Authors: Elgueda Labra Guillermo
Published: November 2022

El objetivo de este ensayo es ofrecer un balance historiográfico acerca de la figura de Arturo Alessandri Palma. En el texto se analizan, fundamentalmente, obras de carácter histórico publicadas en el siglo XX referentes al “León de Tarapacá”, ya sea que trataran su propia efigie o el período en el que desarrolló su acción política. Proponemos que la historiografía participó de manera determinante en la construcción heroica de Alessandri, endosándole, mediante un debate de larga duración, características sobresalientes y susceptibles de utilización política. Esto motivó —como en otras oportunidades— una espontánea y apasionada discusión en 2002 a lo largo de las páginas de El Mercurio, la que situamos en perspectiva histórica.
WHY IS IT REASONABLE TO INVEST IN RENEWABLE ENERGY IN UKRAINE?
Authors: Bashynska Yuliia
Published: November 2022

The purpose of the paper is to present the current status of renewable energy development in Ukraine and to highlight the main advantages of investing in renewables in Ukraine. The purpose is also to reveal the biggest renewable energy installations in Ukraine. The paper displays the main financial initiatives of several international organizations and world economic leaders that have already announced plans to aid Ukraine’s transition to renewable energy. Methology. The survey is based on an analysis of the natural potential, legislative frameworks of the industry and active financial programmes. Results of the survey provide the most attractive opportunities for investing in the emerging market of renewable energy in Ukraine. The survey also shows the amount of economically viable potential of different renewable energy sources. Besides, it is expected that renewable energy will enhance energy security and reduce the negative impact of industry on the environment. Practical implications. Since 2009 when the green tariff was first introduced in Ukraine, the renewable energy sector has been developed to a great extent. Although the sector faced some policy challenges in 2015, such as the imposition of new taxes, but technologies experienced rapid growth. Nowadays the use of renewable energy sources is a priority way of sustainable energy system building in Ukraine. There are several state and regional financial initiatives promoting renewable energy sources. As policymakers have focused on the renewable energy development, new investment centered in energy efficiency technologies. There will be a big step in the direction of renewables usage in private housing complexes. Due to the survey, the main problem of renewable energy development is lack of funding. All the efforts made by the government create an enabling environment for foreign direct investments in renewable energy in Ukraine. Value/originality. Wide renewable energy use would be a good solution for Ukraine to decrease the amount of imported energy resources. Boosting of renewable energy will also help to tackle global warming and negative changes of climate. That is why promoting of renewables use is very important for Ukraine. On the other hand, renewable energy can become a profitable business for investors.
RESEARCH OF THE ENTERPRISE PROFITABILITY STRATEGY
Authors: Shvachych Gennady , Kholod Elena
Published: November 2022

The article focuses on such indicators as profit and profitability, reflecting the economic efficiency of an enterprise, its financial condition, and the problems of its economic development. The subject of the research is to analyse the profitability of an enterprise and validate the strategy of the enterprise’s efficiency increasing. The methodology of the research is based on an analysis of the enterprise efficiency characteristics in general, the profitability of different areas of production. For this purpose, in the economic analysis, in particular, there were used profitability indicators. In this case, profitability is the most generalized, qualitative indicator of the economic efficiency of an entity’s activity, which allows comparing the amount of profit with the value of the means, by which it was obtained. The purpose of the research is to analyse the production activity of OJSC “NmTZ” and to develop proposals for improving its production efficiency; study ways of production development; research factors that delay the growth process of pipe products production; identify the profitability growth factors of the enterprise that allow increasing competitiveness indicators in the pipe market. Practical application. The enterprise’s priority directions of activity aimed at improving the technique and technology on the basis of modern scientific developments in order to reduce energy and material consumption, as well as to improve the quality of pipe products are shown. The key ways of increasing profit and profitability are indicated. Factors of the income increase, which allow the enterprise to carry out its activities more successfully, are revealed.
Superposition of Wave Functions in the G-Qubit Theory
Authors: SOIGUINE Alexander
Published: November 2022

Quantum computing rests upon two theoretical pillars: superposition and entanglement. But some physicists say that this is a very shaky foundation and quantum computing success will have to be based on a different theoretical foundation. The g-qubit theory supports that point of view. Current article is the first one of two and about the superposition principle. Quantum superposition principle states that any two quantum wave functions can be superposed, and the result be another valid wave function. It specifically refers to linearity of the Schrodinger equation. In the g-qubit theory quantum wave functions are identified by points on the surface of three-dimensional sphere . That gives different, more physically feasible, not mysterious, explanation of what the superposition is.
SARAYDAN ÇIKAN BİR JÖNTÜRK: PRENS SABAHATTİN
Authors: KARABAY Ayşenur
Published: November 2022

Sultan II. Abdülhamid’in yeğeni olan Prens Sabahattin, liberal düşüncelere sahip bir fikir adamıdır. Sabahattin Bey, kardeşi Lütfullah Bey ile Abdülhamid’e muhalif olan Jön Türklere katılmıştır. Fikirleriyle özgürlükçü hareketlere öncülük etmiş, II. Abdülhamid iktidarını bitirmek için mücadele vermiştir. II. Meşrutiyet’in ilanından sonra İstanbul’a dönmüş ve aktif bir politikaya girmemiştir. 31 Mart Vak‘ası’na adı karıştığı ileri sürülerek bir süre hapsedildiyse de annesinin ricası ile serbest bırakılmıştır. İttihat ve Terakki yönetiminin siyasî ve iktisadî görüşlerini eleştirmeye devam etmiştir. Türkiye Cumhuriyeti kurulduktan sonra Osmanlı hanedanı mensuplarını sınır dışı eden kanunun yürürlüğe girmesiyle 1924’te yurt dışına çıkmak zorunda kalmıştır. Hayatının son yıllarını İsviçre’de yoksulluk içinde geçiren Prens Sabahattin, 30 Haziran 1948'de İsviçre'nin Neuchâtel kasabası yakınlarındaki bir köyde vefat etmiştir.
AN OVERVIEW OF THE CRASSUS IN TERMS OF WORLD HISTORY ACCORDING TO RUSSIAN SOURCES
Authors: ŞEMŞEK Vesile
Published: November 2022

At the request and promises of the European Catholic Christians of the Pope, VII. The marches they organized to establish military, political and religious authority over the lands of the Middle East, which had been in the hands of Muslims since the 19th century, take place in history as "crusades" or "crusaders". Since Jesus was born in Jerusalem, they called the region and the surrounding lands "holy lands" and declared these marches as holy wars in their way. In addition, Christian soldiers participating in the expedition put the Red Cross on their chests and shields, so they were called "Crusaders". The first and third of the eight crusades left their mark as the heaviest campaign in history. Except for the first and fourth of these campaigns, the kings who dominated all other campaigns also participated. On the other hand, the Crusades were a religious, political, and military operation that started not only against Muslims but also from Western Europe between the XI.- XV. centuries. It started as an effort to save Jerusalem, which they accepted as the Holy city of Christianity in Palestine between 1096-1272. The terms "Crusaders" and "Crusades" in a broader sense are used by the Popes of Rome as a religious-military operation, first against the Seljuk Turks and later against the Ottoman Empire to implement the policy of Christianizing the people of the Baltic states and suppress heretical and anti-religious tendencies in Europe and left its mark on history. The Seljuks, who conquered the Muslim regions of the Middle East, conquered the Byzantine lands, and the Byzantine Emperor IV. The Romans tried to stop the Muslims, but the Byzantine army was crushed in the battle of Manzikert in 1071. After that, the Byzantines no longer had the strength to resist. Slowly advancing westward, the Seljuks continued the Crusades, taking almost all of Asia Minor from Byzantium. In this study, the views and approaches about the crusades in terms of world history were evaluated by examining Russian sources.
Logic and Sets Textbook Containing Ethnomathematics of Sasak Culture: Validation and Design
Authors: Subarinah Sri , Junaidi Junaidi , Triutami Tabita Wahyu , Wulandari Nourma Pramestie , Salsabila Nilza Humaira
Published: November 2022

Ethnomathematics in learning mathematics is a trend that needs to be developed, especially in learning that raises local culture. Mathematics and culture have a very close relationship so the development and application of mathematical concepts in the learning process must be based on situations of daily life or local culture. This study aims to develop logic and sets textbooks containing ethnomathematics of Sasak culture. This book is also oriented toward improving higher-order thinking skills. This research is a Research and Development (R&D) by following the ADDIE development model, namely analysis, design, development, implementation, and evaluation. The first year of this research has been carried out until the development phase, namely by developing textbook products according to the design and validating the textbook products. The results showed that the textbook met the 'Very Good' category in the validity test after being assessed by experts so the textbook was suitable to be used as a learning resource.
Numerical Literacy Skills of Vocational High School Students in Solving HOTS Problems
Authors: Setiani Nurokhmi Wahyu , Asikin Mohammad , Dewi Nuriana Rachmani
Published: November 2022

This study aims to describe the numeracy literacy skills of Vocational High School (SMK) students in solving High Order Thinking Skills (HOTS) problems. The type of research used is descriptive qualitative research. Sampling was done by purposive sampling technique. This research was conducted at SMK Komputama Jeruklegi in XI TKJ 1. Data collection used a numeracy literacy test and interview guidelines. The results showed that students answered correctly on indicator 1 of numeracy literacy by 37.7%; indicator 2 by 31.9%; and indicator 3 by 27.2%. If viewed based on the percentage of each category of HOTS questions, the correct answer in the C4 category (analyze) is 33.9%; category C5 (evaluate) by 28.3%; and category C6 (create) by 32.6%. Based on these results, it shows that students' numeracy literacy skills are still low in solving questions in the HOTS category. The results of this study serve as a reference for teachers and schools to implement more effective and innovative learning so as to improve students' skills in solving problems with higher-order thinking categories. Besides that, it can also be used as a consideration for teachers and students in implementing learning that can foster students' literacy skills.
Development of Interactive Student’s Worksheets to Improve Mathematical HOTS of Tenth Grade Students in Trigonometry Topic
Authors: Sembiring Bertha Oktavika , Napitupulu E Elvis
Published: November 2022

It is undeniable that Higher Oder Thinking Skills (HOTS) have become the center of attention and essential skills needed, especially in mathematics today, but there are so many research shows that the average thinking ability of Indonesian students is still low. One of the student's low thinking abilities cause is teaching materials that still dominated by questions in the Low Order Thinking Skills (LOTS) category. Therefore, this study aims to develop valid, practical, and effective interactive student worksheets to improve tenth-grade students' higher-order thinking skills. This research used Research and Development (R&D) designs and methods guided by the ADDIE development model with five steps: Analysis, Design, Development, Implementation, and Evaluation. The data obtained from this study is quantitative and qualitative data, which was obtained from the interview, validation test sheet, students and teacher response sheet and pretest-posttest result. The assessment from experts from both the material and media shows that the worksheet is valid with 4.30 and 3.97 average scores. Furthermore, based on the questionnaire responses of teachers and students with the "Excellent" score category, it shows that the developed interactive student worksheet is practical. The interactive student worksheet is also effective in improving mathematical HOTS of tenth-grade students since there is a significant increase in students' mathematical higher-order thinking skills based on student learning outcomes with 0.64 value of N-Gain. Besides the N-Gain, the students' response through the learning after using the interactive worksheet was also in the "Excellent" category, with an average score of 4.54 in the small trial and 4.27 in the field trial. Therefore, this study has produced a valid, practical, and effective interactive student worksheet to improve tenth-grade students' mathematical Higher Order Thinking Skills (HOTS).
Cover and Table of Content
Authors: Journal of Mathematics Education AlphaMath:
Published: November 2022

FOREWORDAssalamu’alaikum Wr. Wb.                                                                 Praise the presence of Allah SWT for all the overflow of His Rahmat so that we can publish the journal AlphaMath volume eight number two. The creation of the journal AlphaMath aims to develop the writing culture of educators for both teachers and lecturers. In addition, the journal AlphaMath also seeks to accommodate all aspirations, ideas, and potentials related to the world of education. This journal's publication is in line with the vision and mission of the Mathematics Education Department Universitas Muhammadiyah Purwokerto. The concept and mission are superior in developing the education profession and mathematical competence.The scope of the material in this journal is related to the world of mathematics education. This is to obtain innovations in teaching and ideas from educators to disseminate. Hopefully, this journal will always be evaluated to improve its quality. In this issue, the journal AlphaMath features eleven articles related to model learning, mathematical ability, and ethnomathematics. The authors of the journal come from various educational institutions.Hopefully, this AlphaMath journal can provide benefits for readers and educational actors.Wassalamu’alaikum Wr. Wb.
Gambaran Histologi Hati Ikan Nila (Oreochromis niloticus) Yang Terpapar Pestisida Golongan Organofosfat
Authors: Abdullah Yeni Melia , Handayani Lia , Nurhayati Nurhayati
Published: November 2022

Pestisida golongan organofosfat yang digunakan dalam bidang pertanian untuk membunuh hama dan meningkatkan hasil produksi pertanian untuk memenuhi permintaan pangan yang tinggi akibat meningkatnya populasi penduduk. Akan tetapi penggunaan pestisida golongan organofosfat secara nyata telah meningkatkan hasil produksi, penggunaan yang berlebihan dapat membahayakan organisme akuatik dan mengakibatkan efek jangka panjang terhadap lingkungan perairan. Penelitian ini bertujuan untuk mengevaluasi pengaruh berbagai konsentrasi golongan organofosfat 0,21 ppm; 0,441 ppm; 0,926 ppm; 1.926 ppm; 4,06 ppm; 8,49 ppm terhadap histologi jaringan hati dan ikan nila (Oreochromis niloticus). Pengamatan histologi jaringan hati dan insang memperlihatkan beberapa kerusakan jaringan akibat paparan diazinon, diantaranya: hemoragi, degenerasi hidrofik, kongesti. Penelitian membuktikan bahwa pestisida organofosfat khususnya Diazinon memiliki efek negatif terhadap kelangsungan hidup dan mengakibatkan perubahan histologi jaringan hati ikan nila.
Understanding the Inter-Ethnic Solidarity Formation in A Plural Charismatic Community
Authors: Ismail Rizabuana , Sihombing Grace Prima Apriani , Manurung Ria , Sismudjito Sismudjito , Sitorus Henry
Published: November 2022

This study describes the inter-ethnic solidarity in the charismatic Mawar Sharon church in Medan City, Indonesia, also known as the Connect Group Church.The qualitative and ethnographic approaches were used to determine the solidarity in Charismatic Churches where people are separated by ethnicity. Data were collected through in-depth interviews with respondents actively involved in the activities of the religious connect groups, such as sponsors, coaches, and team leaders. The results showed that the activities in the community include fellowship, ice breakers, praise and worship, and material sharing as a form of learning about inter-ethnic solidarity among members. Furthermore, active members such as team leaders, sponsors, and coaches play significant roles in these activities. Meanwhile, music and church songs are used to strengthen the relationship between members.
Primeras experiencias de monitorización de vancomicina en un Hospital General de Especialidades
Authors: Gómez-De Rueda Félix , Elsegui Horno Inmaculada , Tena-Sempere Mª Eugenia , Gómez-Rodríguez Alicia , Rodriguez Sanz Mª José , Horno-Ureña Florentina
Published: November 2022

Introducción: vancomicina es un antibiótico eficaz para el tratamiento de infecciones por gérmenes grampositivos, sin embargo la toxicidad renal asociada a su uso, ha relegado su utilización a líneas secundarias de uso. Este hecho ha consolidado el tratamiento empírico con antibióticos más caros. Objetivo: analizar los datos de monitorización de vancomicina y valorar la eficiencia frente al uso de otros antibióticos. Método: estudio observacional donde se analiza la monitorización farmacocinética de vancomicina y la eficiencia de una Unidad de Farmacocinética Clínica, con una población de 137 pacientes ingresados en un hospital general de especialidades. Resultados: la utilización de vancomicina en primera intención, supuso un ahorro de 16.472,82€ respecto al uso de daptomicina y de 83.039,83€ respecto al de linezolid. No obstante, el 18% de nuestra muestra no pudo ser tratado con vancomicina, lo que hace necesario disponer de otros fármacos.
Synthesis and cytotoxic activity of tri-acyl ester derivatives of uridine in breast cancer cells
Authors: Berrío Escobar Jhon Fernando , Arango Carmona Victor Hugo , Galeano Jaramillo Elkin , Márquez Fernández Diana Margarita , Márquez Fernández Maria Elena , Camargo Guerrero Mauricio , Martínez Martínez Alejandro
Published: November 2022

Aims: Synthesize tri-acyl ester derivatives of uridine, and evaluate its cytotoxicity against breast cancer cells line. Methods: The tri-esterified uridine derivatives were obtained through Steglich esterification reaction by fatty and aromatic acids, and with acetic anhydride. An acetonide derivative from uridine was prepared with acid catalysis. Compounds were characterized by NMR spectroscopy (1H NMR and 13C NMR), and mass spectrometry. Derivatives were assessed in chinese hamster ovary (CHO-K1) and human breast cancer (MCF-7) cell lines. Results: Five tri-acyl ester derivatives of uridine were obtained one acetic acid, three fatty acids (myristic acid, stearic acid and oleic acid) with an aromatic acid. The uridine per-acetylated and uridine acetonide were obtained in high yields, however, the tri-acyl ester derivatives of uridine with fatty and aromatic acids were obtained in moderate and low yields, respectively. The acetonide and compounds 2 and 3 exhibited a cell viability inhibition significant on both cell lines to the higher concentration. Conclusions: Esterification method with coupling agents allowed obtained tri-acyl ester uridine derivatives with aliphatic and aromatic acids. However, significant cytotoxic activity (p<0.05) for uridine and its derivatives was not observed.
La lucha contra el gusano de Guinea o la recompensa del esfuerzo solidario
Authors: Adroher Francisco Javier
Published: November 2022

Introducción: Dracunculus medinensis o gusano de Guinea es el mayor nematodo parásito del hombre y causa unas úlceras que generan una importante incapacidad durante 2-4 meses, generalmente, que coincide con los periodos de siembra o recogida de las cosechas. Por ello, esta enfermedad, denominada dracunculosis, provoca importantes pérdidas económicas. En sociedades pobres, las más afectadas, estas pérdidas las mantienen en un círculo vicioso de pobreza del que no pueden salir sin ayuda. La dracunculosis forma parte del grupo de enfermedades tropicales olvidadas que, según la OMS, afecta a más de 1000 millones de pobres del mundo. Objetivo: Dar a conocer a la sociedad científica hispanohablante el estado actual de la enfermedad y de su lucha contra ella. Material y métodos: Se ha llevado a cabo una búsqueda bibliográfica en bases de datos científicas, especialmente PubMed (Medline) de la Biblioteca Nacional de Medicina (NML) de Estados Unidos, y se han revisado los informes publicados por los principales organismos e instituciones implicados en la lucha contra la dracunculosis, especialmente The Carter Center, la Organización Mundial de la Salud y Centers for Disease Control and Prevention (CDC) de EE.UU. Resultados: En 1986 se inició una campaña de erradicación basada en las características epidemiológicas de la enfermedad y en la implicación de los países endémicos, lo que permitía plantear ese objetivo, aprobado por la Asamblea Mundial de la Salud en 1981. Este parásito se distribuía por 18 países de África y 3 de Asia, afectando a 5-10 millones de pobres, según la OMS. El esfuerzo solidario de instituciones, fundaciones, empresas y personal, sobre todo voluntario, ha permitido reducir el número de casos en más del 99,99% tras 30 años de campaña. En 2015 se han contabilizado sólo 22 casos limitados a 4 países de África: Malí, Etiopía, Sudán del Sur y Chad. En 2016 se han detectado 25 casos: 16 en Chad, 3 en Etiopía, 6 en Sudán del Sur y ninguno en Malí (datos provisionales1). Conclusión: Se trabaja con la esperanza de que en 2020 la enfermedad esté erradicada del planeta, siendo así la primera de un parásito, mostrándose además que el trabajo de educación sanitaria de la población afectada ha resultado vital para el éxito de la campaña de erradicación.
Análisis bibliométrico de los sistemas de medicación hospitalarios
Authors: Palomo-Linares Benjamín , Palomo-Linares Ruben , Sanz-Valero Javier
Published: November 2022

Objetivo: Análisis bibliométrico de la producción científica sobre los sistemas de medicación hospitalariaen bases de datos internacionales.Método: Estudio descriptivo transversal. Los datos se obtuvieron de las bases de datos MEDLINE (Pub-Med), SCOPUS, COCHRANE LIBRARY y LILACS hasta la fecha actual (2016). El término utilizado enla búsqueda fue “Medication System Hospital”. Se analizaron los principales indicadores bibliométricos,como Descriptores MeSH.Se segmentó la búsqueda por épocas (primera y segunda época, desde el año 1966 hasta 1998 incluido,primera época y desde 1999 a 2016 incluido, segunda época).Resultado: Se obtuvieron 881 referencias recuperadas en 388 revistas. El tipo documental de mayorfrecuencia fue el artículo original. La edad media de los documentos analizados fue de 21,16 años. La distribución geográfica, fue primero estadounidense (EEUU): con 263 trabajos. Las publicaciones con ≥10 trabajos fueron 8. Hubo diferencias significativas entre los descriptores analizados por épocas.Conclusiones: Los estudios sobre los sistemas de medicación hospitalaria son un área temática en decrecimiento, con una gran fragmentación y poco uniforme, sin grandes grupos de referencia ni una basesólida desde la que se puedan continuar estudios posteriores. El inglés es el idioma mayoritario. Los descriptores utilizados son acordes a la temática de estudio.