bluuebunny/crossref_metadata_2025 huggingface dataset:
Perencanaan Sarana Dan Prasarana Pendidikan Islami di Lembaga Pendidikan
Authors: Samanhudi
Published: May 2022

Abstrak

Dalam meningkatkan kualitas pembelajaran di lembaga pendidikan terdapat beberapa factor yang menentukan, mulai dari kurikulum, materi, metode, pendidik, tenaga kependidikan, peserta didik, sarana, prasarana, dan sebagainya. Untuk meningkatkan kualitas pembelajaran dan prestasi peserta didik, diperlukan adanya perencanaan, diantaranya adalah perencanaan sarana dan prasarana pendidikan. Sarana dan prasarana merupakan salah satu factor penting dalam meningkatkan kualitas pembelajaran dan prestasi peserta didik. Sarana dan prasarana seyogyanya disesuaikan dengan kebutuhan dan sejalan dengan visi dan misi lembaga pendidikan itu sendiri. Tulisan ini menjelaskan tentang perencanaan sarana dan prasarana pendidikan Islami. Hal ini perlu dilakukan agar sarana dan prasarana yang disiapkan lembaga pendidikan sejalan dengan nilai-nilai agama Islam. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan analisis deskriptif kualitatif. Kesimpulan dari kajian ini adalah menunjukkan bahwa guna mencapai tujuan pendidikan diperlukan adanya sarana dan prasarana pendidikan, meliputi perencanaan, tujuan dan manfaat, perinsip perencanaan, prosedur, klasifikasi, pengadaan sarana dan prasarana pendidikan. Pengadaan sarana dan prasaran yang direncanakan akan menghasilkan sarana dan prasarana yang baik dan tepat guna, sehingga proses belajar mengajar akan berhasil dengan dukungan sarana dan prasarana yang memadai.

Abstract

In improving the quality of learning in educational institutions, there are several factors that determine, starting from the curriculum, materials, methods, educators, education staff, students, facilities, infrastructure, and so on. To improve the quality of learning and student achievement, planning is needed, including planning for educational facilities and infrastructure. Facilities and infrastructure are one of the important factors in improving the quality of learning and student achievement. Facilities and infrastructure should be tailored to the needs and in line with the vision and mission of the educational institution itself. This paper describes the planning of Islamic education facilities and infrastructure. This needs to be done so that the facilities and infrastructure prepared by educational institutions are in line with Islamic religious values. The method used in this research is qualitative with a qualitative descriptive analysis approach. The conclusion of this study is to show that in order to achieve educational goals it is necessary to have educational facilities and infrastructure, including planning, objectives and benefits, planning principles, procedures, classification, procurement of educational facilities and infrastructure. Procurement of planned facilities and infrastructure will produce good and effective facilities and infrastructure, so that the teaching and learning process will be successful with the support of adequate facilities and infrastructure.
Genealogy of Religious Study Program of Uin Ar-Raniry Aceh in Developing the Values of Religious Moderation
Authors: Mawardi
Published: May 2022

This study aimed to describe the genealogy of the Religious Studies Program of UIN Ar-Raniry Aceh in developing the value of religious moderation. Religious moderation is an attitude, perspective, mindset, and way of behaving in carrying out religion with the nature of tawassuth (middle), tawazun (balanced), and tolerance. In principle, the purpose of religious moderation is harmony. In Indonesia, the development of religious studies in other higher education institutions is encouraging news so that the search for religious conventions can provide more alternatives. This study was conducted using a qualitative method that produces descriptive data with a phenomenological approach. Data collection techniques used were observation, interviews, and documentation with inductive data analysis. The results showed that the Indonesian government’s efforts to ground the values of religious moderation through the mouthpiece of the Ministry of Religious Affairs have strategic values, but it is not as easy as turning the palm, it will solve the intolerance problem.
Mielominės ligos ir inkstų ląstelių karcinomos metastazių diferencinė diagnostika
Authors: Sakalauskė Diana , Augustaitytė Agnė , Aukštakalnienė Asta
Published: May 2022

Dauginė mieloma (DM) – tai piktybinis navikas, kuriam būdinga plazminių ląstelių proliferacija kaulų čiulpuose. 2018 m. Europos farmacijos pramonės ir asociacijų federacijos (angl. EFPIA) duomenimis, 100 000 Lietuvos gyventojų tenka 6,2 dauginės mielomos atvejai per metus. Dauginė mieloma diagnozuojama esant histologiškai patvirtintai plazmocitomai (kai kaulų čiulpuose randama > 10 proc. plazminių ląstelių klono) ir bent vienam dauginės mielomos požymiui: CRAB (hiperkacemija, inkstų funkcijos nepakankamumas, anemija arba lizinės kaulų pažaidos), kaulų čiulpų kloninė plazmocitozė ≥ 60 proc., serume dalyvaujančių ir nedalyvaujančių lengvųjų grandinių santykis ≥ 100 arba > 1 lokali pažaida MRT. Dauginė mieloma ir naviko metastazės kauluose – tai dvi histologiškai skirtingos patologijos, kurių abiejų pažeidimo vieta yra kaulų čiulpai. Šias ligas sunku diferencijuoti, nes abiejų metu pasireiškia panašūs klinikiniai simptomai, tokie, kaip nugaros skausmas arba stebimi kaulų lūžiai, bei radiologiniuose tyrimuose stebimi įvairūs liziniai pokyčiai. Sergant inkstų ląstelių karcinoma, yra didesnė tikimybė išsivystyti ML nei bendrojoje populiacijoje bei atvirkščiai – sergant ML, didesnė tikimybė inkstų ląstelių karcinomos vystymuisi.
Besitęsiančios COVID-19 pandemijos poveikio vaikų ir paauglių psichikos sveikatai tyrimas
Authors: Leskauskas Darius , Juodenis Dainius , Savulionytė Evelina
Published: May 2022

Tyrimo tikslas. Įvertinti, kokį poveikį vaikams ir paaugliams, kuriems diagnozuoti psichikos ir elgesio sutrikimai, turi antrus metus besitęsianti COVID-19 pandemija. Tyrimo metodika. Lietuvos sveikatos mokslų univertiteto ligoninės Kauno klinikų (Kauno klinikų) Nervų ligų ambulatorinio skyriuje (NLAS) bei Vaikų ir paauglių psichiatrijos sektoriuje (VPPS) konsultuojami ir gydomi pacientai, kurių amžius 11–17 metų ir jų tėvai (globėjai). Pasirinktų pacientų protinis amžius ≥ 10 metų, jiems diagnozuotas raidos, elgesio arba psichikos sutrikimas, dėl kurio buvo kreipiamasi į vaikų ir paauglių gydytoją psichiatrą. Tyrimui naudotos dvi (vaikų ir tėvų, globėjų) apklausos anketos. Apklausa vykdyta 2021 m. gegužės–spalio mėn. Duomenų rinkimui naudoti standartizuoti klausimynai. Analizuoti duomenys pateikiami pagal aprašomąją statistiką. Tyrimo rezultatai. Analizei naudotos 54 vaikų ir 49 tėvų anketos, rezultatai parodė, kad, nepaisant stabilizavusios COVID-19 pandemijos situacijos, išlieka neigiami psichikos ir elgesio sutrikimų simptomai: suintensyvėjusios elgesio problemos, vienišumo bei nerimo pojūčiai. Rezultatai rodo, kad 79,3 proc. vaikų patyrė elgesio (impulsyvumo, dirglumo, nedėmesingumo) sunkumų, 55,6 proc. jautė intensyvų nerimą, 87,0 proc. jautėsi vieniši.
Pokovidinis sindromas vaikų amžiuje
Authors: Žėkaitė-Vaišnienė Erika , Siratavičienė Aurelija , Kėvalas Rimantas
Published: May 2022

2019 m. pasaulyje prasidėjo SARS-CoV-2 viruso sukelta pandemija, kuri sukėlė daug iššūkių visai medikų bendruomenei. Augant COVID-19 infekcija persirgusių žmonių skaičiui, stebimi nauji su infekcija susiję liekamieji reiškiniai, kurie apibūdinami kaip pokovidinis sindromas. Vaikų amžiuje dėl negebėjimo apibūdinti, ką pacientas jaučia, šį sindromą įtarti ir diagnozuoti gali būti sudėtinga. Straipsnio tikslas – apžvelgti naujausius pokovidinio sindromo vaikų amžiuje literatūros duomenis. Metodika. Mokslinių darbų paieška atlikta naudojant kompiuterinę bibliografinę mokslinių darbų bazę „PubMed“, taip pat remtasi tarptautinių gairių ir oficialių organizacijų duomenimis. Analizuoti publikuoti moksliniai tyrimai ir straipsniai. Paieškose buvo vartojami reikšminiai žodžiai ir jų deriniai: long covid, post-covid conditions, covid infection in children. Rezultatai. Tiksli pokovidinio sindromo epidemiologija dar nežinoma, tačiau manoma, kad beveik pusė vaikų, persirgusių COVID-19 infekcija, jaučia ilgiau nei 12 savaičių išliekančius simptomus. Dažniausi aprašomi pokovidinio sindromo simptomai yra nuovargis ir dėmesio koncentracijos stygius, tačiau simptomų įvairovė didelė. Gydytojai ir pacientų tėvai turėtų atkreipti dėmesį į suprastėjusius vaiko pasiekimus, pasikeitusį elgesį, nuotaiką ir ieškoti kompetentingos pagalbos.
Gydytojų pervargimas COVID-19 pandemijos laikotarpiu ir prevencijos būdai. Literatūros apžvalga
Authors: Janonytė Viktorija , Navickaitė Aistė , Česnulevičienė Aistė
Published: May 2022

Tyrimo tikslas. Išanalizuoti dažniausiai literatūroje aprašomas gydytojų pervargimo COVID-19 pandemijos laikotarpiu prevencijos priemones ir jų veiksmingumą. Tyrimo metodas. Sisteminė literatūros apžvalga. Atrinkti straipsniai, kuriuose aprašomas gydytojų pervargimas COVID-19 infekcijos metu ir prevencijos priemonės. Apžvalga atlikta naudojantis elektronine duomenų baze „PubMed“ („Medline“). Straipsniams iškelti tinkamumo kriterijai: straipsnis neturėjo būti senesnis nei trejų metų, straipsnyje turėjo būti pateikiama informacija apie gydytojų pervargimą ir prevencijos būdus. Išanalizuoti mokslinių publikacijų literatūros šaltiniai, siekiant įvertinti naujausią medžiagą. Rezultatai. Buvo nagrinėjami šeši tyrimai. Trys iš jų atlikti JAV, kiti atlikti Malaizijoje, Brazilijoje ir Anglijoje. Sisteminės literatūros apžvalgoje buvo ieškoma veiksmingų prevencijos būdų, kurie padėtų kovoti su pervargimu. JAV po atlikto serologinio tyrimo nerimas ir baimė susirgti COVID-19 liga sumažėjo. Kitame tyrime gydytojai, dalyvaujantys vaidmenų modeliu pagrįstoje informavimo programoje, pabrėžė, kad tai yra priimtinas, veiksmingas ir naudingas būdas palaikyti emocinę gerovę. Trečiame tyrime, remiantis „Mirčių kavinė“ modeliu, tikimasi, jog tai gali būti veiksminga priemonė, siekiant išvengti gydytojų pervargimo. Malaizijoje atliktas tyrimas, kuriuo gilinamąsi į infekcijų kontrolės sustiprinimą. Pakoregavus taisykles bei sudarius tinkamus darbo grafikus, atsižvelgiant į darbo krūvį, darbuotojų baimė bei tikimybė pervargti sumažėjo. Pagal apklausos rezultatus, Anglijoje atliktame tyrime buvo įkurta poilsio erdvė medicinos personalui, kuri sumažino pervargimo sindromo susidarymo tikimybę. Paskutiniame Brazilijoje nagrinėtame straipsnyje vertinta kanabidiolio nauda. Medikamentas sumažino nerimo, depresijos ir emocinio išsekimo simptomus. Visuose nagrinėtuose straipsniuose prevencijos būdai buvo veiksmingi arba iš dalies veiksmingi. Svarbu paminėti, kad kol kas yra mažai publikacijų apie prevencijos priemonių taikymą gydytojams, kuriems pasireiškia perdegimo sindromas. Išvados. Literatūroje nagrinėjamos veiksmingos prevencijos priemonės yra šios: „Mirčių kavinės“ modelis, AAP priemonių didinimas, stiprinamos ligoninės taisyklės, tinkami darbo grafikai, profilaktiniai serologiniai tyrimai, vaidmenų modeliu pagrįsta informavimo programa, profilaktinis kanabidiolio vartojimas, poilsio vietos įrengimas. Visuose nagrinėtuose straipsniuose prevencijos priemonės buvo veiksmingos arba iš dalies veiksmingos, mažinant perdegimo sindromo išsivystymo tikimybę. Tiriamieji pabrėžė sumažėjusį nerimą, baimę, emocinį išsekimą, depresiją, padidėjusį bendruomenės ryšio jausmą bei koncentraciją darbe.
Pengujian Penetrasi pada Windows 10 menggunakan Model Penetration Testing Execution Standard (PTES)
Authors: Andhika Delfan Azhar , Slamet  , Ningsih Norma
Published: May 2022

Windows 10 adalah sistem operasi yang digunakan oleh banyak orang, organisasi dan perusahaan. Windows 10 sendiri memiliki bug (kerentanan) saat pertama kali diinstal oleh pengguna. Bug (kerentanan) ini dapat mengganggu proses yang ada, beberapa pengaturan tidak berfungsi sebagaimana mestinya kemudian jika bug (kerentanan) digunakan untuk sesuatu yang tidak legal, juga dapat menyebabkan data tidak dapat diakses (ransomware), menghapus data pengguna hingga merusak sistem Windows 10 itu sendiri. Solusinya adalah dengan melakukan pengujian penetrasi pada sistem operasi Windows 10 dan menemukan bug (kerentanan) sesuai dengan metode yang digunakan yaitu model Penetration Testing Execution Standard (PTES), menggunakan tools yang sesuai tahapan pada model Penetration Testing Execution Standard (PTES). Hasil pengujian penetrasi menggunakan model Penetration Testing Execution Standard (PTES) menunjukkan bahwa dengan tools yang tepat, peneliti dapat mencari bug (kerentanan) yang ada pada sistem Windows 10 dan menambalnya.
EVALUATION OF THE MATHEMATICAL MODELLING METHODS AVAILABLE IN THE MARKET
Authors: Gaidelys Vaidas , Naudžiūnaitė Emilija
Published: May 2022

The major purpose of this research is to analyse and select the relevant mathematical modelling methods that will be employed for developing an algorithm. To fulfil the major purpose, three following objectives were raised. First, to select and substantiate the most common mathematical modelling methods. Second, to test the pre-selected meth-ods under laboratory conditions so that the most relevant method for implementing the target project could be identi-fied. Third, to prepare at least 3 models for application. The research results indicate that when evaluating the respira-tory virus (SARS-CoV-2 causing COVID-19) concentration and survival rate dependence on a number of traits, the methods of descriptive statistics, confidence intervals, hypothesis testing, dispersion analysis, trait dependence analysis, and regression analysis are employed. All the above-listed methods were tested under laboratory conditions and thus can be applied to evaluate the effectiveness of the project product – a device designed to prevent transmission of res-piratory viruses through air droplets. Selection of a particular method depends on a set of traits to be analysed, a trait type (quantitative, qualitative), a trait distribution type, and parameters. In the context of COVID-19, there is an urgent need to bring new products to market. Since most of the new products developed are directly related to research, it is very important to calculate the algorithms required to provide the service. Therefore, in order to calculate the optimal algorithm, it is necessary to analyze the algorithms already on the market. In this way, the products developed can gain a competitive advantage over competitors’ products. Given that the equipment placed on the market will be equipped with HINS radiation sources, such a product will become original and new on the market. Therefore, it is necessary to evaluate several methods of mathematical modelling. It is also necessary to take into account that the placing on the market of a product takes place in the context of global competition.
ASSESSMENT OF THE FACTORS INFLUENCING THE DIGITALIZATION OF ECONOMIES IN THE BALTIC STATES
Authors: Stecenko Inna , Stukalina Yulia
Published: May 2022

Digitalization of the world economy is accompanied by a comprehensive digital transformation of all business processes. However, the speed of digital transformation varies across countries. The aim of the research was to identify the main factors influencing the pace of digitalization of economies in the three Baltic States. The research is based on Eurostat’s data from 2014 to 2020. For evaluating the factors that may impact the level of digitalization of economies in Estonia, Latvia and Lithuania the authors carried out a Pearson correlation analysis, using SPSS software. The research results indicate that in the context of the digitalization of the economy, the factors directly linked to the level of GDP are the number of specialists involved in the R&D sector and use of the Internet for banking operations. The findings of the study are supposed to be used for the development of a policy for business digital transformation in the Baltic States.
STUDY ON THE ELIGIBILITY OF VENTURE CAPITAL FUNDS IN THE UNITED STATES MARKET
Authors: Pakšytė Ieva , Jurevičienė Daiva
Published: May 2022

Experience shows that 9 out of 10 start-ups and SMEs do not survive in the market and fail at an early stage. This study aims to fill a gap on how start-ups and SMEs are affected by venture capital fund investments, i.e., identifying the criteria for selecting a potentially best VCF, ensuring the success of the investment and reducing pos-sible bankruptcy risk. The object is VCFs in the United States. The data was used from a publicly available statistical database Crunchbase. Using the complex proportional assessment method CORPAS for evaluating and ranking VCF criteria and the cluster analysis – for identifying similarities between VCFs and dividing VCF into clusters, the inves-tigation determines the crucial criteria. The most important are: Years in business of VCF; The number of employees working for VCF; The fund’s marketing strategy. The study results can help further to develop an evaluation system of VCF eligibility criteria.
EDUCATIONAL ATTAINMENT AND ECONOMIC GROWTH IN EVIDENCE FROM NEW EU MEMBER STATES
Authors: Sart Gamze , Bayar Yilmaz , Sezgin Funda Hatice
Published: May 2022

Educational attainment is a crucial factor underlying economic growth and development. In this study, the mutual interaction between educational attainment and economic growth is investigated in sample of the new Europe-an Union member states, which experienced a structural transformation in institutional, economic, and political fields, over the 1996–2019 term by means of causality test. The consequences of causality analysis revealed a bidirectional causal interaction between educational attainment and economic growth. In other words, on the one hand educational attainment has a significant influence on economic growth, on the other hand economic growth has a significant influ-ence on educational attainment.
CONCAVE EFFECT OF FINANCIAL FLEXIBILITY ON SEMICONDUCTOR INDUSTRY PERFORMANCE: QUANTILE REGRESSION APPROACH
Authors: Chang Bao-Guang , Wu Kun-Shan
Published: May 2022

To survive increasingly uncertain and competitive markets, technology and capitalintensive semiconductor companies need to be more agile, responsive and flexible than ever before. This study investigates the impact financial flexibility on firm performance within Taiwan’s semiconductor industry and whether the impact on FP differs depending on the semiconductor industry characteristics. Using quantile regression analysis, data from semiconductor companies listed on the Taiwan Stock Exchange during the COVID-19 shock was investigated. The results evidence an inverted U-shaped relationship between FF and FP in the lower and median return on equity quantiles of the semiconductor industry. For the asset heavy business model companies, FF has a concave impact on FP for IC-design and IC-manufacturing companies but not the semiconductor companies. For the asset light business model companies, FF has a concave impact on FP in the lower and median quantiles for semiconductor companies, in the upper quantiles for IC-design companies and in all except the 90th quantile for IC-manufacturing companies. The results of this research significantly contribute to extant literature as with such specific knowledge regarding the impact of FF on FP, managers are able to make decisions based on a firm’s individual FF-FP relationship and identify the most lucrative business trajectory.
Phytochemical extraction and comparative analysis of antioxidant activities of Areca catechu L. nut extracts
Authors: Kumar A Ajesh , Abuthahir S.S. Syed , Aboul-Enein Hassan Y.
Published: May 2022

FRAP assay proved all the extracts ofAreca catechuL. nut have antioxidant properties because IC50values of all the extracts of the same were less than that of ascorbic acid. Remaining antioxidant assays like DPPH radical scavenging assay, H2O2scavenging assay, and Fe2+chelating assay showed more antioxidant properties in ethyl acetate extract and nonpolar solvent extracts like n- hexane, and chloroform respectively. Antioxidant properties ofAreca catechuL. nut varied depending upon the different solvent extract.
Solutions to the non-cutoff Boltzmann equation uniformly near a Maxwellian
Authors: Silvestre Luis , Snelson Stanley
Published: May 2022

The purpose of this paper is to show how the combination of the well-known results for convergence to equilibrium and conditional regularity, in addition to a short-time existence result, lead to a quick proof of the existence of global smooth solutions for the non cutoff Boltzmann equation when the initial data is close to equilibrium. We include a short-time existence result for polynomially-weighted $ L^\infty $ initial data. From this, we deduce that if the initial data is sufficiently close to a Maxwellian in this norm, then a smooth solution exists globally in time.
Tecnologías médicas asociadas a la transfusión sanguínea en tiempos de autarquía: el aparato transfusor del Dr. Agustí Amell (1943)
Authors: Hervás Puyal Carlos
Published: May 2022

Tras la Guerra Civil española, durante el período de grave crisis económica conocido como la época de la “autarquía”, la importación de instrumental médico-quirúrgico, entre otras muchas materias, se vio prácticamente imposibilitada. Ello favoreció la aparición de múltiples propuestas por parte de profesionales españoles para suplir aquellas carencias.
Se presenta una muestra de esta tendencia a partir de un modelo de aparato para las transfusiones sanguíneas diseñado por el médico catalán Agustí Amell, junto con otros varios proyectos similares y contemporáneos. Con el objetivo de averiguar el papel desempeñado por esta tecnología se ha realizado una investigación basada en la utilización de fuentes primarias (documentación de archivos) y publicaciones médicas de la época, así como bibliografía secundaria para su debida contextualización.
La herencia de Prometeo. Las enfermedades ocupacionales en el Corpus Hippocraticum
Authors: Sierra Martín César
Published: May 2022

El presente trabajo analiza las enfermedades ocupacionales en el Corpus Hippocraticum. Principalmente nos centraremos en Epidemias, que recoge numerosas historias clínicas, con el objetivo de analizar la asistencia sanitaria de los trabajadores en la médica griega. Finalmente, abordamos el debate historiográfico en torno al acceso a la sanidad en el mundo antiguo.
Desarrollo de modelos estadísticos para la predicción de propiedades mecánicas del hormigón simple
Authors: Gadve Sangeeta , Jajodia Rangesh
Published: May 2022

La resistencia a la compresión del hormigón se considera una propiedad índice del hormigón y, por lo tanto, otras propiedades mecánicas del hormigón, como la resistencia a la flexión y el módulo de elasticidad, están correlacionadas con ella. Las prácticas del código estándar de diferentes países proporcionan correlaciones empíricas entre la resistencia a la compresión y las propiedades mecánicas. Sin embargo, se observa que estas correlaciones arrojan resultados desviados. El presente artículo tiene como objetivo desarrollar modelos estadísticos para estimar con precisión estas propiedades en base a resultados experimentales. Las muestras de cubos, cilindros y vigas de concreto simple se moldean con una relación agua-cemento y una relación agregado-cemento variables. Con base en los resultados experimentales, se desarrollan los modelos de predicción de la resistencia a la compresión, la resistencia a la flexión y el módulo de elasticidad. Los resultados experimentales se comparan con los resultados obtenidos a partir de modelos estadísticos generados, así como con los resultados disponibles de la literatura. Se encuentra que los modelos actuales predicen con precisión las propiedades mecánicas de los hormigones.
Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development
Authors: Wang Yue-yi , Nie Li , Xu Xiao-xiao , Shao Tong , Fan Dong-dong , Lin Ai-fu , Xiang Li-xin , Shao Jian-zhong
Published: May 2022

Retinoic acid–inducible gene I (RIG-I) is an important cytosolic pattern recognition receptor crucial for sensing RNA virus infection and initiating innate immune responses. However, the participation of RIG-I in cellular development under physiological conditions remains limited. In this study, the regulatory role of RIG-I in embryonic hematopoiesis was explored in a zebrafish model. Results showed that rig-I was ubiquitously expressed during embryogenesis at 24 h postfertilization (hpf). A defect in RIG-I remarkably disrupted the emergence of primitive hematopoietic precursors and subsequent myeloid and erythroid lineages. In contrast, RIG-I deficiency did not have an influence on the generation of endothelial precursors and angiogenesis and the development of mesoderm and adjacent tissues. The alteration in these phenotypes was confirmed by whole-mount in situ hybridization with lineage-specific markers. In addition, immunostaining and TUNEL assays excluded the abnormal proliferation and apoptosis of hematopoietic precursors in RIG-I–deficient embryos. Mechanistically, RIG-I regulates primitive hematopoiesis through downstream IFN signaling pathways, as shown by the decline in ifnφ2 and ifnφ3 expression, along with rig-I knockdown, and rescue of the defects of hematopoietic precursors in RIG-I–defective embryos after administration with ifnφ2 and ifnφ3 mRNAs. Additionally, the defects of hematopoietic precursors in RIG-I morphants could be efficiently rescued by the wild-type RIG-I but could not be restored by the RNA-binding–defective RIG-I with site mutations at the RNA-binding pocket, which are essential for association with RNAs. This finding suggested that endogenous RNAs may serve as agonists to activate RIG-I–modulated primitive hematopoiesis. This study revealed the functional diversity of RIG-I under physiological conditions far beyond that previously known.
Covid-19 y medios de comunicación: voces para un análisis crítico
Authors: Barrientos-Báez Almudena
Published: May 2022

Reseña del libro "Covid-19 y medios de comunicación: voces para un análisis crítico" de Carmen Marta-Lazo, Miguel Ángel Ortiz-Sobrino, María Gómez y Patiño, Juan Carlos González Pérez (Sindéresis, 2020).
The Numerical Solution of Poisson Equations using Wavelet based Multigrid Method
Authors: Angadi L. M.
Published: May 2022

The potential energy field produced by a given charge or mass density distribution is described using the Poisson equation. This study presents a numerical solution to the Poisson equation using a wavelet-based multi-grid approach. The proposed method is superior to the existing method in terms of fast convergence and reduced processing time. Some of the problems are used to show the method's applicability and validity.
Validación de un cuestionario acerca de las prácticas de ocio familiar
Authors: Álvarez-Muñoz José Santiago , Hernández-Prados Mª Ángeles
Published: May 2022

El ocio familiar está adquiriendo un protagonismo en el ámbito socioeducativo que se ve revertido en el volumen de estudios científicos, no obstante, son insuficientes los instrumentos cuantitativos, centrados principalmente en la medición de la frecuencia de actividad. Ante ello, el presente trabajo, tomando como referencia el marco teórico del ocio como recurso educativo y de desarrollo humano, expone los pasos seguidos para el proceso de diseño y validación de un cuestionario inicial compuesto por 73 ítems por medio de la participación de 14 jueces expertos en metodología de investigación, atendiendo parcialmente modelo empírico descrito Muñiz y Fonseca-Pedrero y empleando la técnica Delphi de validación de expertos. De esta forma, el instrumento inicial, cada uno de los ítems, se sometió a una valoración en base a tres criterios clave: adecuación, pertinencia y claridad. La mayoría de los ítems obtiene valores cercanos a la perfección en los tres descriptores a excepción de unos pocos que fueron modificados de redacción, ampliados con clarificaciones o ejemplificaciones o directamente eliminados. Finalmente, una vez analizadas las valoraciones cualitativas y cuantitativas, se diseñó la versión definitiva del cuestionario compuesto por 50 ítems agrupados en seis dimensiones, obteniendo altos índices de fiabilidad tanto general como de forma específica en cada una de sus dimensiones. La creación de este instrumento contribuye a materializar la teoría del ocio y la familia en el terreno empírico, otorga así la posibilidad de poder evidenciar desde la investigación directa lo establecido por los supuestos teóricos.
The BUAS BUAS LEAF UTILIZATION OF BUAS BUAS LEAF (Premna pubescens Blume) ETHANOL EXTRACT AS LIQUID SOAP WITH ANTI-BACTERIA ACTIVITY
Authors: Rafita Rafita Yuniarti , Munandar Nasution Haris , Rani Zulmai , Fahmi Fahmi
Published: May 2022

The buas buas (Premna pubescens Blume) plant is from the Lamiaceae family. The use of ethanol extract of buas buas leaf (Premna pubescens Blume) as soap is because soap is one of the health products needed by many people to maintain a healthy body. It is used as an antibacterial because buas buas leaves contain secondary metabolites that can be used as antibacterial.The Buas buas leaf Simplicia (Premna pubescens Blume) was extracted using 96% ethanol by maceration and concentrated with a rotary evaporator to evaporate the solvent. The concentrated extract obtained was tested by phytochemical screening, formulated into liquid soap with concentrations of 5%, 10%, 15% and tested for pH, foam height, viscosity, specific gravity and irritation test, and antibacterial activity against staphylococcus aureus bacteria. The results of the phytochemical screening test of the ethanol extract of buas buas leaf (Premna pubescens Blume) contained secondary metabolites in the form of alkaloids, flavonoids, saponins, tannins and steroids/triterpenoids. Liquid soap made with concentrations of 5%, 10%, and 15% has a pH of 10-10.3; foam height 50-90 mm; viscosity 1210-1290 cP; specific gravity 1-1.08 and did not cause irritation to volunteers; and have inhibitory power of 14.2 mm, 15.0 mm, 16.0 mm, and 20.0 mm against Staphylococcus aureus bacteria, respectively.
An updated review on microspheres: a suitable drug carrier in sustained release drug delivery
Authors: Srivastav Sachin , Kumar Kapil , Joshi Aparna , Teotia Deepak , Ikram Ikram
Published: May 2022

With advances in biotechnology, genomics, and combinatorial chemistry, a wide variety of new, more potent and specific therapeutics are being created. Because of common problems such as low solubility, high potency, and/or poor stability of many of these new drugs, the means of drug delivery can impact efficacy and potential for commercialization as much as the nature of the drug itself. Thus, there is a corresponding need for safer and more effective methods and devices for drug delivery. Microspheres having particle size in range between 0.1-200 µm, can be delivered by several routes like oral, parentral, nasal, ophthalmic, transdermal, colonal etc.  In future by combining various new strategies, microspheres will find a central place in novel drug delivery, particularly in diseased cell sorting, genetic materials, safe, targeting and effective drug delivery.
The Traditional and Pharmacological Properties of Solanum nigrum: a Review
Authors: Mani Rupesh Kumar , J B Paramashree , D R Bharathi , Ahmed Syed Sagheer
Published: May 2022

Solanum nigrum has a place in the Solanaceae family with a common name of garden nightshade. It is composed of a variety of glycoalkaloids, glycoproteins, polysaccharides and polyphenolic mixtures such as gallic acid, catechin, protocatechuic acid, and caffeic acid, epicatechin, and rutin. Solanum nigrum have hepatoprotective, antitumor, immunomodulatory, anti-ulcer, calming, hostile to convulsant, cardio defensive, antibacterial, antidiabetic and pain-relieving impacts. Traditional medicine in India and other parts of the globe has used Solanum nigrum to treat liver disorders, constant skin sickness, fiery circumstances, menstrual cramps, fevers, diarrhoea, eye infections, dizziness and other diseases.
TIME-DRIVEN ACTIVITY-BASED COSTING (TDABC): UMA REVISÃO SISTEMÁTICA DA LITERATURA
Authors: Diehl Cabral Pedro Henrique , Viegas Neto Carlos , Leal de Souza Ângela Rozane
Published: May 2022

Este estudo buscou revisar a literatura sobre o método de custeio Time-Driven Activity-Based Costing, de modo a verificar o estado da arte da temática, analisando seu desenvolvimento ao longo dos 16 anos após a primeira publicação de Kaplan e Anderson, que ocorreu em 2004. O enquadramento metodológico desta pesquisa é qualiquantitativo, com objetivo descritivo, e foi adotado o procedimento de Revisão Sistemática da Literatura. Os estudos-alvo da revisão foram obtidos por meio das bases de dados Web of Science e Scopus. Após terem sido aplicados os critérios de filtragem, pormenorizados na seção do método, obteve-se uma amostra contendo 102 artigos, distribuídos em 75 periódicos científicos. Os resultados apontaram uma expressiva vantagem quantitativa das publicações voltadas à área da saúde e à carência por pesquisas em outros setores prestadores de serviços e indústrias de modo geral. Ao longo das análises, são discutidas oportunidades para estudos futuros, entre os quais o aprofundamento teórico necessário à temática, cuja produção científica tem se concentrado em pesquisas de caráter empírico. Nesse sentido, destaca-se o campo das Ciências Contábeis como bem posicionado para o adequado endereçamento das carências teóricas que foram referidas na literatura consultada.
ORÇAMENTOS E CONTROLE GERENCIAL: UM LEVANTAMENTO SOBRE DISCUSSÕES CONTEMPORÂNEAS
Authors: Queiroz André Felipe , Dos Santos Bortolocci Espejo Marcia Maria , Paniagua Mendieta Fabio Henrique
Published: May 2022

Desde o surgimento das teorias administrativas os gestores se preocupam com as diferentes funções administrativas como o planejamento e o controle. Para tal, diferentes artefatos são utilizados, como métodos de custeio, indicadores financeiros, e também o orçamento. Nesse seguimento, este trabalho tem como objetivo identificar as discussões contemporâneas e os gaps teóricos atuais na perspectiva orçamentária do controle gerencial. Foi empregada uma revisão sistemática sobre artigos publicados e revisados por pares, nos últimos sete anos que utilizaram orçamentos e o estudo sobre controle gerencial. Os resultados demonstram que a discussão contemporânea sobre orçamentos e controle gerencial é bem ampla e apresenta diversas demandas para pesquisa e quais são as possibilidades de pesquisas. Este trabalho contribui para a sistematização dos assuntos que necessitam de investigação sobre a temática.
Does Split-Body Resistance Training Routine Performed Two Versus Three Days Per Week Induce Distinct Strength and Morphological Adaptations in Resistance-Trained Men? A Randomized Longitudinal Study
Authors: Felipe Alves Brigatto  , Júlio Benvenutti Bueno de Camargo  , Yuri Benhur Machado  , Moisés Diego Germano  , Marcelo Saldanha Aoki  , Tiago Volpi Braz  , Charles Ricardo Lopes
Published: May 2022

The purpose of this study was to investigate the chronic effects of training muscle groups, through a split-body routine on 2 versus 3 days per week, on neuromuscular performance and morphological adaptations in resistance-trained men with the number of sets per muscle group equated between conditions. Twenty healthy men (28.8 ± 6.1 years [range 19 to 37 years]; 172.8 ± 5.1 cm; total body mass = 70.2 ± 7.4 kg; RT experience = 3.5 ± 0.8 years [range 2 to 5 years]; RT frequency = 4.4 ± 0.5 session·wk-1) volunteered to participate in this study. Subjects were randomly assigned into 2 experimental groups: (1) 2 sessions·wk-1 per muscle (G2x, n = 10), in which every muscle was trained twice a week with 9 sets or (2) 3 sessions·wk-1 per muscle (G3x, n = 10), in which every muscle was trained thrice a week with 6 sets. All other variables were held constant over the 8-week study period. No significant difference between conditions for maximal strength in the back squat and bench press, muscle thickness of the biceps brachii, triceps brachii, vastus lateralis and anterior quadriceps (rectus femoris and vastus intermedius) was detected. In conclusion, both G2x and G3x significantly enhance muscular adaptations, with a similar improvement noted between experimental conditions.
Revista de Morfologia Urbana
Authors: Saboya Renato Tibiriçá de , Netto Vinicius de Moraes , Ventorim Fernanda Careta
Published: May 2022

Este número da Revista de Morfologia Urbana representa um marco importante em sua história e nos esforços dos seus editores, desde sua criação, para atingir os níveis mais altos de excelência em publicação científica. Mais especificamente, marca a transição para o modelo de publicação contínua dos artigos aceitos após a revisão por pares, sem a necessidade, portanto, de aguardar o fechamento de um volume completo para a publicação completa e simultânea de todos os artigos que compõem uma edição.
Peranan E-Commerce terhadap Pengembangan model proses rekruitmen murid baru maupun akselerasi pembelajaran kelompok bermain & Taman Kanak-kanak Delta Asih Pertiwi, Waru Sidoarjo
Authors: Setyadarma Bambang , Poernomo Tri Tjahjo , Putri Husni Indrawati Wijaya
Published: May 2022

Studi pendahuluan yang telah dilakukan atas persiapan kegiatan pengabdian masyarakat ini, yaitu melakukan kajian dasar terhadap sisi penerapan e-commerce terhadap proses rekruitmen murid baru maupun aktivitas pembelajaran di KB & TK Delta Asih Pertiwi, Waru Sidoarjo. Hal ini merupakan suatu strategi manajemen aktual bagi pengembangan sektoral kompetensi antar kelembagaan KB & Tk di lingkup kecamatan Waru Sidoarjo guna mengembangkan potensi segment pasar baru di dunia pendidikan kelompok bermain maupun taman kanak-kanak di masa pandemik saat ini. Dimana aktualisasi penerapan e-commerce mampu menjawab tantangan zaman, guna memenuhi peningkatan akselerasi pengembangan metode pengajaran serta proses rekruitmen murid baru berupa sarana kemudahan bagi masyarakat guna mengakses maupun memahami betapa pentingnya keberadaan e-commerce di era pandemik dewasa ini. Dimana upaya peningkatan daya kompetensi dunia pendidikan kelompok bermain dan taman kanak-kanak dapat berlangsung secara berkesinambungan dalam jangka panjang. Aktualisasi program e-commerce tersebut dapat diwujudkan dalam bentuk blogger ataupun website yang sangat mendukung sekali terkait program pengajaran di KB & TK Delta Asih Pertiwi. Hal ini bertalian erat terhadap relevansi konseptual inti model pembelajaran modern dalam bentuk in bound maupun out bound guna memenuhi standart kelayakan gugus ajar. Terkait proses pemberdayaan pengajaran yang berkualitas modern didukung oleh visioneritas kelembagaan Delta Asih Pertiwi sebagai wahana pengembangan pola kreativitas berpikir/ sensor motorikal secara profesional bagi anak didik berusia balita agar menjadi sosok siswa yang mandiri dan berkepribadian intelektual berdedikasi modern sesuai dengan globalisasi era milenial dewasa ini.
PKM Pembinaan meningkatkan karakter siswa SMP Negeri 9 Sibolga menimbulkan jiwa kewirausahaan
Authors: Hutagalung Heriyawan , Simamora Fauziah Nur
Published: May 2022

: Judul pengabdian adalah Pembinaan Meningkatkan Karakter Siswa SMP Negeri 9 Sibolga Menimbulkan Jiwa Kewirausahaan. Mitra pengabdian ini adalah siswa sekolah menegah pertama negeri 9 sibolga. Tujuan pelaksanaan program kemitraan masyarakat ini adalah (1) Pemahaman program kemitraan masyarakat ditengah siswa SMP 9 Sibolga, (2) pemahaman dalam pengetahuan kewirausahaan, (3) pemahaman pengelolaan manajemen dalam kewirausahaan, (4) meningkatkan karakter siswa dalam mengembangkan jiwa kewirausahaan sejak siswa menengah pertama. Metode yang digunakan adalah metode pembelajaran eksperimental dan konsep studi kepustakaan tentang jiwa kewirausahaan. Penyampaian berupa ceramah, diskusi sehingga orang dapat berpartisipasi aktif dalam kegiatan ini. Dalam pelatihan disajikan materi: Konsep jiwa kewirausahaan dan karakter. Setelah melakukan kegiatan ini, peserta cukup responsif dan antusias dalam mengikuti materi pelatihan, sebagaimana dibuktikan oleh banyaknya pertanyaan yang diajukan oleh para peserta dan ada rencana bisnis yang dibuat untuk membuatnya setelah mendapatkan pelatihan. Program ini dilakukan salah satu upaya untuk menambah wawasan  ilmu pengetahuan dalam berwirausaha. Kegiatan ini juga berguna sebagai meningkatkan karakter siswa dalam jiwa kewirausahaan.
Peningkatan mutu pengajaran Sekolah Dasar melalui pemanfaatan teknologi integratif
Authors: Sinaga Poltak , Augustinus Daniel Cassa , Ferawaty Ferawaty , Alfonsius Alfonsius , Ginting Sryani Br. , Damanik Rudolfo Rizki , Kaban Lila Maria
Published: May 2022

Pada awal terjadinya pandemi COVID 19, telah terjadi banyak hal yang mengakibatkan perubahan di tengah masyarakat. Salah satunya adalah di kegiatan belajar mengajar. Berangkat dari hal tersebut maka pada pertengahan Agustus 2020 dimulailah satu kegiatan untuk membantu para guru yang ada di daerah untuk bisa beradaptasi dengan perubahan terkait kegiatan belajar mengajar pada masa pandemi. Kegiatan ini dilaksanakan dalam beberapa bulan dengan dua kegiatan utama dilaksanakan secara daring dan kegiatan pendampingan juga secara daring. Pada April 2021 didapatkanlah hasil dari kegiatan ini yang sebagian besar menilai kegiatan positif dan membantu dalam aplikasi kegiatan belajar mengajar. Hanya saja yang disayangkan kegiatan ini tidak menjangkau banyak peserta.
ФОРМАЛНО ОПИСАНИЕ НА СЛОВООБРАЗУВАТЕЛНИТЕ СТРУКТУРИ
В НОРМАТИВНАТА ГРАМАТИКА НА БЪЛГАРСКИЯ ЕЗИК /
FORMAL DESCRIPTION OF WORD-FORMATION STRUCTURES
IN BULGARIAN NORMATIVE GRAMMAR
Authors: MALDZHIEVA VYARA MALDZHIEVA
Published: May 2022

This work proposes principles for the formal description of word-formation structures in a synchronic study within the framework of normative grammar.
One of the basic postulates of normative grammar is the independence of the de-scription of form and meaning, which is motivated by relative, though sufficient, au-tonomy of the structure of meaning (semantic structure) and of the formal structure of complex language units. This study takes for granted the existence of structural isomorphism between clauses and derived lexemes. In the context of the description of word-formation phenomena, this means that – in parallel to what is found in clause syntax, which distinguishes between the conceptual structure of a clause and the clausal form – both semantic structure and formal structure are assigned to derived lexemes. The consistent implementation of this distinction leads to defining word-formation as morphemic syntax (similar to sentence syntax) and derived words as structures within which rules for formal and semantic combination of morphemes are applied.
The attempt at developing a model for formal derivational structures presented in the paper is based on the formal features of derivational exponents. These features serve to derive the following dichotomic division criteria:
1) affixal – +/- attachment of a given type of affix to the stem;
2) confixal – +/- attachment of two affixes to the stem;
3) alternating – +/- qualitative stem alternation;
4) reductional – +/- stem reduction;
5) paradigmatic – +/- attachment to the stem of a grammatical morpheme other than the one in the derivational base.
Keywords: formal description, formal word-formation structures, normative grammar
ПРОСТИ СИНТАКТИЧНИ ГРУПИ С ГЛАВЕН ЧЛЕН ПРИЛАГАТЕЛНО ИМЕ И ПОДЧИНЕН ЧЛЕН
СЪЩЕСТВИТЕЛНО ИМЕ / SIMPLE SYNTACTIC GROUPS FORMED BY A HEAD ADJECTIVE
AND A SUBORDINATE NOUN
Authors: STOILOVA ILIANA
Published: May 2022

The article discusses simple syntactic groups formed by a head adjective and a subordinate noun in Bulgarian. The author proposes a formal description of these groups within the framework of normative grammar. The study is focused on the processes of syntactic accommodation that describe the formation of grammatical constructions consisting of a head adjective and a subordinate noun.
Keywords: simple syntactic groups, formal description, syntactic accommodation, adjectives, nouns, Bulgarian language
Sleep Quality in Patients of Chronic Tension Type Head Ache: Report from a Tertiary Care Facility
Authors: L Gopichandran , C Kanniammal , G Valli , M Jaideep , A Srivastava , P Vanamail , M Dhandapani
Published: May 2022

Present study was undertaken with the objective of identifying sleep quality among patients with Chronic tension type headache (CTTH) and to identify various factors influencing sleep quality among patients with CTTH. Using consecutive sampling technique, a cross-sectional study was conducted on 169 patients who were diagnosed with CTTH in a tertiary care centre in North India to assess the sleep quality and its associated factors in patients of CTTH. Pittsburgh Sleep Quality Index (PSQI) was used to assess the sleep quality of the patients. Wong Backer Foundation Pain intensity scale was used to assess the severity of pain. The mean PSQI in patients with CTTH was 15.59+1.19. All 169 patients enrolled in the present study were found to have poor sleep quality as their total PSQI was more than or equal to five. All patients reported less than five hours of night sleep, more than 60 minutes of sleep latency (time taken to fall asleep), less than 75 percent sleep efficiency, sleep disturbances up to twice a week, day time dysfunction due to daytime sleepiness and low enthusiasm three or four times a week. The common causes of prolonged sleep latency reported were pain, bad dreams and nocturia. All patients reported that they use sleep medications (prescribed or over the counter), out of which five percent reported the use of sleep medication more than three times a week and rest (95%) reported the use of sleep medication less than once a week. There was a significant positive correlation between PSQI and headache duration (r=0.39, p
Effectiveness of an Educational Intervention on the Knowledge and Attitude of Patients Attending the DOTS Centre of Selected Hospitals in Mangaluru, Karnataka
Authors: Dsilva Fatima
Published: May 2022

Tuberculosis (TB) is still a major cause of mortality and morbidity in India due to widespread ignorance and negligence among the public. The present study evaluated the effectiveness of an educational programme on knowledge and attitude of tuberculosis, as clarity of information among the public can further curb the devastating illness. A pre-experimental design was adopted for the study; 50 patients attending the DOTS Centre of selected hospitals and PHCs at Mangaluru were selected using purposive sampling. The data was collected from Feb till May 2016. A self-administered knowledge questionnaire consisting of 30 items and a 21-item, 5-point attitude scale were the instruments used for the study. A cut off score of > 13 was considered as having average knowledge and a cut off score of > 84 was considered as having negative attitude. An educational talk for 45 minutes was organised for the patients attending the DOTS centres. Among 50 TB patients, only 23 (46%) knew that TB is curable and 31 (62%) knew that it is a communicable disease. 28 (56%) patients didn’t know that DOTS is the main treatment for TB; 45 (90%) had negative attitude in the pre-test. No significant association was found between the demographic variables and knowledge and attitude (p>0.05). The educational programme was found to be effective in enhancing the knowledge and bringing a change in the attitude (t79=2, p<0.05). Nurses are powerful agents of change and can utilise education as one of the cost effective intervention for promoting health among tuberculosis patients.