bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcriptome Analysis of Metapenaeus affinis Reveals Genes Involved in Gonadal Development
Authors: Zhang Yan , Li Yun-Dong , Yang Qi-Bin , Jiang Song , Jiang Shi-Gui , Zhou Fa-Lin
Published: August 2022

Metapenaeus affinis is a crustacean with important commercial value in the fishery of the South China Sea. Overfishing has resulted in the decline of the wild population and germplasm degradation. However, there is little background knowledge about its gonadal development, and there is a lack of research on the development of this species. To better understand the molecular regulatory mechanisms during gonadal development, here, we performed RNA-Seq on immature and mature ovaries and compared their transcriptomic signatures. 126,930,488 and 122,677,356 clean sequencing reads were obtained from the Illumina sequencing platform, respectively. 394 differentially expressed genes (DEGs) were identified, of which 136 were up-regulated, and 258 were down-regulated. Further analysis revealed rich transcriptional sequences, which have homology with genes related to reproduction and development. Expression patterns of COX, GPX, E3s, PCNA, STPK, and other genes were changed during ovarian development. Validation by qRT-PCR demonstrated the reliability of RNA-Seq. This study has made a significant contribution to the currently available sequence data of M. affinis and provided reference data for the development of genetic and breeding work.
Implementasi Algoritma Noekeon Untuk Mengamankan File Audio
Authors: Tita Azwinar Sarumaha
Published: August 2022

Along with the development of an increasingly advanced era, and supported by the development of very rapid information technology, especially in producing audio files, it can now be done with smartphone devices. With the application on smartphones with devices to make audio both for private and public. Audio files need to be secured with better security, in order to anticipate if the account is far from being in the hands of unauthorized people, one way to secure audio files is by using cryptographic techniques, with this technique, unauthorized people cannot see the information contained in the audio. the. One of the algorithms that can be used to secure audio files is the NOEKEON algorithm, Noekeon is a repeating block cipher with a block length and key length of 128 bits each, which consists of a simple round transformation application that repeats itself, followed by an output transformation. Noekeon has 16 rounds (Nr) iterations in each round four transformations are carried out, namely, Theta, shift offset consisting of two transformations Pi1 and Pi2 and gamma The advantages of the Noekeon algorithm do not limit the keys used or use these keys to exploit into cipher text and avalanche effects obtained meet the strict Avalanche criterion. If there is an error in one block cipher it cannot affect the other blocks
Akurasi Algoritma Fletcher-Reeves untuk Prediksi Ekspor Karet Remah Berdasarkan Negara Tujuan Utama
Authors: Sinaga Rapianto , Malemta Sitomorang Mora , Setiawan Deri , Wanto Anjar , Perdana Windarto Agus
Published: August 2022

Crumb rubber is a natural rubber specially designed to ensure its technical quality. Rubber is produced mainly in Southeast Asia, where Indonesia is the second largest producer in the world after Thailand. This study aims to predict the export of powdered rubber in Indonesia. The prediction method used is FletcherReeves which is one of the artificial neural network methods commonly used to predict data. The research data used is crumb rubber export data by main destination country for the period 2012-2020 which was obtained from the website of the Indonesian Central Statistics Agency. Based on this data, network architecture models will be trained and defined, including 7-10-1, 7-15-1, 7-20-1, 7-25-1, 7-30-1 (trancgf). Of the five models, after training and testing, the best data architecture model is 7-15-1 (trancegf) 7 is the input layer, 15 is the number of neurons in the hidden layer and 1 is the exit layer. The level of accuracy of the architectural model with the MSE value is 0.00482054.
TÜRKİYE’DEKİ İŞLETMELERDE BİLİŞİM TEKNOLOJİLERİ KULLANIMI: SORUNLAR VE ÇÖZÜM ÖNERİLERİ
Authors: Karahan Mehmet , Bürkek Nuray
Published: August 2022

Bilgi toplumuna dönüşüm hedefinde bilgi ve iletişim teknolojisi çok önemli ve güncel bir konuma sahiptir. Zamanımız dinamik rekabet ortamında işletmelerin yaşamlarını sürdürebilmeleri geliştirecekleri stratejilere bağlı olup, güvenli bilgilere ihtiyaç duyduklarında erişmeleri ve bunları işletmenin içindeki ve dışında bulunan birimlerine ulaştırabilmeleri de oldukça önemlidir. Bu bağlamda örgüt için hayati derecede önemli olan bilgi akışının etkili bir şekilde sağlanmasında bilişim teknolojilerinin önemi rolü vardır. Bu çalışmada, Türkiye’deki işletmelerde 2021 yılı BT kullanımı araştırması, işletmelerin bilgisayar, internet ve diğer bilişim teknolojilerini kullanım durumları, teknolojik yeterlilik ve uyumları hakkında bilgi toplamak, karşılaşılan sorunları belirlemek ve bu sorunlara çözüm önerileri geliştirmek amacıyla yapılmıştır. TUİK tarafından yapılan anket çalışması sonucunda elde edilen bulgulara göre, girişimlerin internet erişim oranları (%95,3) oldukça yüksek olup bu oran çalışan sayısı arttıkça artmaktadır. İşletmelerin web sitesi olanların oranı %49,4 olup bunların çoğunluğu (%98) web sitesini mal ve hizmetleri hakkında bilgi ve fiyat listelerini sunmak üzere kullanılmaktadır.
PANDEMİ DÖNEMİNDE TEMEL İHTİYAÇLARIN ARTAN ÖNEMİ: MASLOW’UN İHTİYAÇLAR HİYERARŞİSİ BAĞLAMINDA BİR DEĞERLENDİRME
Authors: Özkanan Arzu
Published: August 2022

Covid-19 pandemisi ilanı ile birlikte insanların yaşamında köklü bir değişiklik yaşanmıştır. Bu çalışma ile çalışma yaşamında meydana gelen değişimlerin motivasyon üzerindeki etkilerini tespit etmek amaçlanmıştır. Araştırma sosyal mesafe önlemlerinin sosyal varlık olan insana etkileri, insanın temel ihtiyaçlarını yeniden önceleme çabası ve motivasyonlarının değişimini ortaya çıkarması açısından önemlidir. Araştırma, Batı Akdeniz’de yer alan devlet üniversitelerinde görev yapan, dönüşümlü – uzaktan – esnek çalışma uygulamasında yer almış 48 idari personel ile yarı yapılandırılmış görüşme formu aracılığıyla yapılmıştır. Bulgulara göre katılımcılar zihinlerinde etki olarak yer eden pandemi döneminde Maslow’un ihtiyaçlar Hiyerarşisinde birinci basamakta yer alan fizyolojik ihtiyaçları karşılayarak motivasyonlarını sağlayabilmişlerdir. Aynı zamanda üçüncü basamakta yer alan sevgi ve ait olma ihtiyacına verilen önemde de artış görülmektedir. Bu doğrultuda çalışanlar dönüşümlü – esnek – uzaktan çalışma sonrasında ise motivasyonlarını işyerlerine dönmeleri ile sağlayabileceklerini ifade ederek ait olma ihtiyacını yansıtmaktadırlar. Diğer taraftan çalışanların sosyalleşme konusundaki arzuları, onların eskisi gibi bir araya gelebilmeyle dahi motive olabileceklerini anlatmaktadır. Çalışanların motivasyonlarını yeniden oluşturabilmenin yolu öncelikle bu ihtiyaçlara yönelmekle mümkün olabilecektir.
FASEOLAMINA, MOLÉCULA DE INTERÉS EN LA INDUSTRIA ALIMENTARIA Y FARMACÉUTICA, UNA REVISIÓN.
Authors: Díaz Byron , Baquero María Fernada , Rubio Sebastian , Díaz Ronald
Published: August 2022

Esta investigación se propuso revisar el estado del arte alrededor de la Faseolamina, molécula extraída de Phaseolus vulgaris, de interés para la industria alimentaria y farmacéutica, por su efecto inhibidor sobre las enzimas α-amilasas. La información se rastreó con estas palabras clave: “Faseolamina”, “Inhibidores de α-amilasa”, “Phaseolus vulgaris”, “Reducción de peso”, “Diabetes” en plataformas digitales de las editoriales Wiley Online Library, Springer Nature, MDPI, Taylor Francis, Sage y Google Académico. Se definieron tres ejes de interés, los métodos de extracción de la Faseolamina, las condiciones óptimas de inhibición y la estructura de la molécula. Se determinó mayor pureza molecular con el método de extracción con presión de vacío con dióxido de carbono supercrítico, sin toxicidad ni cambios en el sabor. La inhibición promedio sobre α-amilasas es 91,10% en estudios In vitro e In vivo a nivel gastrointestinal, a un pH de 5,5 y una temperatura de 37º C. Químicamente la Faseolamina es una glicoproteína tetramérica, rica en ácido aspártico, ácido glutámico, serina, treonina y valina, contiene los tres compuestos de lectinas del fréjol: Fito-hemaglutininas (PHA), Arcelinas y los tres inhibidores de α-amilasa. Presenta alta inhibición de α-amilasa intraluminal y duodenal, podría usarse en productos alimenticios y farmacéuticos.
UNICyTios UNICyT incubator of startup - Año 2021, Vol. 2
Authors: Ramos Sánchez Erick
Published: August 2022

Esta publicación electrónica recoge los proyectos realizados por estudiantes de Licenciatura que ofrece la Universidad Internacional de Ciencia y Tecnología (UNICyT) durante el periodo académico 02-2021. Estos modelos de negocio son el producto de las ideas innovadoras propuestas por los estudiantes en el curso Design Thinking, Startup y Lean Canvas, y tienen como principal objetivo, la inserción de nuestros estudiantes al mundo del emprendimiento y la innovación. Todos estos trabajos fueron presentados previamente por los estudiantes en Ferias de Emprendimiento que la UNICyT organiza y que forman parte de las actividades de extensión orientadas al fortalecimiento de capacidades para el emprendimiento de los estudiantes de Licenciatura de la UNICyT. Se estimula a los estudiantes desde el curso de Design Thinking, Startup y Lean Canvas a desarrollar ideas innovadoras. El proceso culmina con las presentaciones de los estudiantes a los miembros de la comunidad universitaria en un formato de ferias que la universidad ha denominado UNICyT Incubator of Startups - UNICyTios. Adicionalmente a la presentación oral en modo PechaKucha, todos los participantes presentan un manuscrito que cumple la normativa exigida en el curso, 29 de ellos están publicados en este e-book. La necesidad de diseñar y desarrollar modelos de negocios que respondan a una dinámica de mercado en la que convergen productos, servicios, experiencias y significados, y a una dinámica social que privilegia a la persona por sobre las organizaciones, ha dado lugar a nuevos enfoques teóricos y metodológicos. En este sentido, el programa se ha propuesto la aplicación de la metodología de Design Thinking, Startup y Lean Canvas para la creación de una empresa novedosa en un espacio de capacitación, reflexión y aprendizaje a través de la combinación de conocimiento, práctica y exploración en un proceso participativo. El programa combina la documentación y formación conceptual con talleres y workshops que tienen como objetivo dominar la praxis de las técnicas de Design Thinking, Startup y Lean Canvas aplicadas a la Innovación. Los 29 modelos de negocio publicados en esta edición recogen los resultados del curso Design Thinking, Startup y Lean Canvas realizado por 29 estudiantes que aplicaron los conocimientos adquiridos durante su formación en la carrera y en el curso CE 011 001 Design Thinking, Startup y Lean Canvas sobre la metodología basada en una comunicación interactiva multilateral y participativa, como parte de la solución de los problemas de las comunidades.
O Potencial da gestão da logística reversa de resíduos sólidos em organizações públicas de saúde
Authors:   , Marques Rodrigo de Sousa
Published: August 2022

Esta pesquisa teve por propósito evidenciar o potencial da Gestão da Logística Reversa de resíduos sólidos em duas unidades públicas de saúde do município de Manaus-AM. Para isso, utilizou-se de dados secundários mediante a aplicação de questionários e entrevistas em profundidade a atores envolvidos direta ou indiretamente nessa área, além da análise observacional de campo. Os dados apurados indicam que as gestões ainda têm longo caminho a percorrer, no que tange à utilização da logística reversa. Isso porque o processo reverso ainda não é de conhecimento das administrações estudadas, mesmo estas apresentando resíduos com alto potencial de absorção pela logística, de tal modo que tal fato tem contribuído para outros pontos críticos observados no gerenciamento dos resíduos das unidades. Palavras-chave: Logística Reversa. Resíduos Sólidos. Gestão Pública.
Challenges Faced by Patients while Undertaking Treatment for Tuberculosis
Authors: Batra Suveera , Parwar Pallavi
Published: August 2022

Despite the immunisation of 92% of the Indian population against tuberculosis with the bacille Calmette-Guerin vaccine (Statistica, 2019), India recorded 79,000 deaths due to this bacterial infection (The Times of India, 2020). Professionals in the field have tried to find the reason behind  the high mortality and high infection rate in the country with the aim of eliminating tuberculosis in India by 2025 as part of the TB National Strategic Plan. A significant reason identified for this phenomenon is non-adherence to treatment due to challenges faced by the patients while undertaking treatment. The aim of the present research study is to identify the challenges faced by  Indian tuberculosis patients visiting a dispensary in South Delhi undertaking treatment for tuberculosis and evaluating their relative importance in influencing their treatment experience through a mixed-method approach. The study was carried out by conducting a survey via phone with 35 Tuberculosis patients. Financial difficulties/loss of job/ school was found to have the highest mean rating which mirrors the trend in other developing countries such as Bangladesh. The study has implications for the government at different levels and private hospitals can be convinced that providing free-of-cost treatment is not enough and more budget should be allocated to tuberculosis treatment to ensure that patients receive a wholesome diet during and post-treatment. These changes combined would be a great step to improving public health crises such as the transmission of infectious diseases in developing countries like India.
LA POLÍTICA DE EMPLEO JUVENIL ACTUAL: ANÁLISIS JURÍDICO-LABORAL DEL PROGRAMA DE PRIMERA EXPERIENCIA PROFESIONAL EN LAS ADMINISTRACIONES PÚBLICAS
Authors: REQUENA MONTES OSCAR
Published: August 2022

En el presente trabajo se presenta una revisión ordenada e interrelacionada de las iniciativas más emblemáticas e influyentes en materia de formación y empleo juvenil de la última década, partiendo del punto de vista de la Unión Europea y revisando el modo en que se han incorporado sus directrices en el marco estratégico y normativo español. Dicho recorrido antecede al análisis crítico del contenido del nuevo "programa de primera experiencia profesional en las administraciones públicas", comparando su régimen jurídico con el del contrato en prácticas y advirtiendo de la potencialidad de dicho periodo para favorecer la carrera laboral en las Administraciones Públicas.

Lan honetan, azken hamarkadako gazteen prestakuntza eta enplegu arloko ekimen enblematiko eta eraginkorrenen berrikuspen txukuna eta elkarri lotutakoa aurkezten da, Europar Batasunaren ikuspuntutik abiatuz eta Espainiako estrategia- eta arau-esparruan norabideak sartzeko moduak berrikusiz. Aipatutako ibilbidea "administrazio publikoetan lehen lanbide-esperientzia izateko programa" berriko edukiaren analisiaren aurrekoa da; berea praktiketarako kontratuaren araubide juridikoarekin konparatzen du eta Administrazio Publikoetako lan-ibilbidearen alde egiteko denboraldi horren potentzialtasunaz ohartarazten du.

This paper presents an orderly and interrelated review of the most emblematic and influential initiatives in the field of training and youth employment of the last decade, starting from the point of view of the European Union and reviewing the way in which its guidelines have been incorporated in the Spanish strategic and regulatory framework.Said journey precedes the critical analysis of the content of the new "program of first professional experience in public administrations", comparing its legal regime with that of the internship contract and warning of the potential of said period to favor a career in Public Administrations.
LOS CONFLICTOS DE INTERÉS COMO RIESGOS PARA LA INTEGRIDAD: DIFICULTADES Y RECOMENDACIONES PARA SU PREVENCIÓN EN EL SECTOR PÚBLICO
Authors: BAENA GARCÍA LARA
Published: August 2022

Las organizaciones públicas a menudo presentan dificultades para gestionar eficazmente los conflictos de interés que surgen y evitar que desemboquen en actos de abuso de la posición o el cargo público en beneficio privado. Por un lado, la falta de comprensión de lo que estos conflictos implican y un amplio desconocimiento de cómo los sesgos cognitivos pueden llevarnos a infravalorarlos dificultan la correcta declaración de estos riesgos. Por otro lado, las organizaciones públicas a menudo crean barreras en lugar de allanar el camino para detectar estas situaciones y tratarlas a tiempo. Este artículo examina estas dificultades individuales y trabas organizacionales para proponer recomendaciones prácticas para superarlas y avanzar hacia estrategias de prevención de los conflictos de interés más efectivas.

Entitate publikoek askotan aurkezten dituzte sortzen diren interes gatazkak eraginkorki kudeatzeko eta onura pribaturako maila edo kargu publikoaren abusuak gertatzea saihesteko zailtasunak. Alde batetik, gatazka horiek ekartzen dutena ez ulertzeak eta isuri kognitiboak gu horiek gutxiestera eramateko modua ez jakiteak arrisku horien adierazpen zuzena zailtzen dute. Bestetik, entitate publikoek askotan oztopoak sortzen dituzte, egoera horiek antzemateko eta garaiz konpontzeko, bidea erraztearen ordez. Artikulu honek zailtasun indibidual eta entitateen oztopo horiek aztertzen ditu, horiek gainditzeko eta interes gatazka efektiboagoak prebenitzeko estrategietarantz aurrera egiteko gomendio erabilgarriak proposatzeko.

Public organizations often have difficulties in effectively managing conflicts of interest and preventing them from leading to acts of abuse of public office for private gain. On one hand, a lack of understanding of what conflicts of interest entail as well as a spread unawareness of how cognitive biases can lead us to underestimate conflicts and make it difficult for individuals to declare these risks. On the other hand, public organizations often build barriers rather than pave the way to early detection and management of these situations. This paper analyses these individual difficulties and organizational obstacles and suggests practical recommendations to overcome them and move towards more effective conflict of interest prevention strategies.
EMBAJADORAS/ES DEL CONOCIMIENTO DE LA JUNTA DE ANDALUCÍA. UNA NUEVA FORMA DE ENTENDER LA GESTIÓN DEL CONOCIMIENTO EN UNA ORGANIZACIÓN COMPLEJA
Authors: DOMÍNGUEZ MURILLO FRANCISCO JAVIER
Published: August 2022

La gestión del conocimiento es una disciplina relativamente reciente si nos referimos a su aplicación en los procesos y relaciones de las administraciones públicas. En este artículo se muestra la implantación de un programa novedoso basado en el aprendizaje por proyectos, que pretende difundir esta disciplina en una organización compleja y extensa como la Junta de Andalucía. El programa Embajadoras/es del Conocimiento de la Junta de Andalucía impulsa proyectos de gestión del conocimiento con carácter transversal a la organización, con un fuerte componente de trabajo colaborativo, realizado por personas que, de manera voluntaria y a través de convocatorias, se adscriben a proyectos que dan respuesta a retos reales y con el objetivo de que la cultura de compartir vaya calando progresivamente en la organización. Tras las cinco ediciones llevadas a cabo, 142 profesionales han sido formados en la disciplina de gestión del conocimiento, se han impulsado 13 proyectos y se han elaborado un total de 75 entregables.

Jakintzaren kudeaketa nahiko diziplina berria da, administrazio publikoetako prozesuetan eta harremanetan aplikatzeaz ari bagara. Artikulu honetan, diziplina hori erakunde konplexu eta handi batean, Andaluziako Juntan, zabaldu nahi duen programa berritzaile baten ezarpena erakusten da; proiektukako ikaskuntzan oinarritutako programa baten ezarpena, zehazki. Andaluziako Juntaren Jakintzaren Enbaxadoreak programaren bidez, erakundean jakintza kudeatzeko proiektuak sustatzen dira zeharkakotasunez, neurri handi batean lankidetza-lanean oinarrituta. Lan hori egiten duten pertsonak boluntarioak dira; zenbait deialdiren bitartez, benetako erronkei erantzuteko proiektuetara atxikitzen dira, erakundean partekatzeko kultura gero eta gehiago barneratzea lortzeko helburuarekin.

Knowledge management is a rather recent concept when it comes to its application to processes and relationships within the scope of the public administration. This article presents the implementation of an innovative program focused on project-based learning, which aims to spread this idea over the Junta de Andalucía, a very complex and extensive organization. The Andalusian Government's program Ambassadors of Knowledge promotes knowledge management projects which are transversal to the organization. Genuinely based on cooperative work, these projects are carried out by people who join them voluntarily by means of public calls and answer to real-life challenges aiming that a new culture of sharing progressively permeates the organization. After five editions, 142 professionals have been trained in the discipline of knowledge management, 13 projects have been promoted and a 75 deliverables have been produced.
Coriocarcinoma primario de estómago. Reporte de un caso
Authors: Mondragón Vera Jhon Alberto , Avilés Meléndez Manuel , Portanova Ramírez Michel , Kapsoli Sánchez María
Published: August 2022

El corioadenocarcinoma gástrico primario (PGC) constituye menos del 1% de todos los cánceres gástricos; es más común en los hombres. Aproximadamente un tercio de los pacientes ya tienen enfermedad metastásica en el momento del diagnóstico. Presentamos el caso de un paciente varón de 70 años, diagnosticado de adenocarcinoma gástrico en antropíloro, al que se le realizó gastrectomía radical distal. El diagnóstico anatomopatológico muestra un adenocarcinoma, con un 85% de diferenciación coriocarcinomatosa, un 10% con áreas de adenocarcinoma tubular y el 5% restante por componente sugestivo de tumor de saco vitelino. Nuestro paciente logró una sobrevida de 5 meses después de la cirugía, durante este tiempo estuvo en seguimiento por medicina oncológica con quimioterapia. Esta enfermedad sigue teniendo un pronóstico sombrío; menor a 6 meses.
Crisis celíaca y tetania aguda en pediatría. Reporte de un caso
Authors: Sbruzzi Agustina del Rosario , Torres Federico , Sommaruga Horacio , Ameri Camila , Yarcho Maria , Gonzalez Maria Fernanda
Published: August 2022

La enfermedad celíaca es una enfermedad sistémica inmunomediada, con un gran espectro de presentaciones clínicas. El término crisis celíaca describe la forma aguda y potencialmente fatal. Clínicamente se caracteriza por diarrea severa, deshidratación y alteraciones metabólicas. Se reporta el caso de un paciente masculino de 7 años de edad que asiste a guardia con tetania, edema en miembros inferiores, esteatorrea y pérdida de peso de 8 meses de evolución, con hallazgos analíticos de hipocalcemia, hipomagnesemia, hipopotasemia y coagulopatía. El diagnóstico de crisis celíaca se realizó sobre la base de hallazgos serológicos y clínicos compatibles con enfermedad celíaca en el contexto de anomalías metabólicas graves y desnutrición aguda, confirmado posteriormente por anatomía patológica. La importancia de este repor n repasar las características de esta grave entidad, que requiere un elevado índice de sospecha para su diagnóstico.
Evaluación de un test del aliento con carbono 13 para el diagnóstico de Helicobacter pylori Test del aliento con carbono 13 para H. pylori
Authors: Bernui Vigo Grazia María , Del Aguila Gamarra Lorena Alexandra , Sanes Guevara María Fátima , Prochazka Zarate Ricardo , Bussalleu Rivera Alejandro
Published: August 2022

Objetivo: Evaluar un test del aliento con carbono 13 de fabricación China como método diagnóstico no invasivo para la infección por Hpen población peruana a través de la determinación de sensibilidad, especificidad, valor predictivo positivo y negativo, likelihood ratio positivo y negativo y utilidad diagnóstica. Materiales y métodos: Se realizó un estudio transversal y descriptivo sobre una base de datos secundaria del Servicio de Gastroenterología del Hospital y Clínica Cayetano Heredia de noviembre de 2017 a agosto de 2018. Se incluyó a pacientes mayores de 18 años sometidos a una endoscopía digestiva alta. Resultados: Se halló una sensibilidad de 90,3% (IC 95,0% 0,81-0,96), especificidad de 82,5% (IC 95,0% 0,67-0,93), valor predictivo positivo y negativo de 90,3% y 82,5%, y likelihood ratio positivo y negativo de 5,16 y 0,12, respectivamente. El área bajo la curva ROC fue 0,88 (IC 95,0%: 0,80 – 0,96). Conclusiones: El test del aliento con carbono 13 es una prueba no invasiva y sencilla que proporciona resultados de forma rápida. Sin embargo, no es posible recomendar el uso rutinario de esta prueba debido a la discrepancia entre los resultados internacionales y locales obtenidos. Se sugiere realizar estudios con mayores tamaños muestrales, protocolos estandarizados y de diferentes fabricantes para evaluar su rendimiento y características.
Perfil clínico-patológico de pacientes con cáncer hepatobiliar en dos hospitales de referencia en Lima, Perú
Authors: Machicado Claudia , Guerrero Harold A. , Casas Fresia , Pajuelo Monica J. , Acevedo Laura , Samame Juan Carlos , Medina Nicolas , Machicado Jorge D. , Marcos Luis A.
Published: August 2022

Objetivo: El objetivo del estudio fue describir las características clínico-patológicas de individuos diagnosticados de cáncer de hígado, vías biliares o vesícula. Materiales y métodos: Entre el 2006 y 2017, se diagnosticaron 89 pacientes (57% mujeres; media: 62 años) con estos canceres en dos hospitales nacionales de Lima, Perú. Resultados: Los resultados mostraron que, independientemente del tipo de cáncer, 64% de los participantes habían sido diagnosticados en estadios avanzados. La anemia fue más frecuente en los pacientes con cáncer de vías biliares e hígado y en estadios avanzados. Se observó mayor frecuencia (32%) de hipertensión arterial (HTA) en el grupo con cáncer de hígado. El análisis por edad mostró que en los pacientes mayores de 50 años la HTA fue más frecuente. Asimismo, sujetos menores de 50 años reportaron antecedentes de infecciones previas en mayor frecuencia (50%), siendo Hepatitis B (HBV) la más común. Conclusiones: Este estudio describe las características clínico-patológicas de base de una neoplasia poco estudiada en el ámbito nacional.
Tree Preservation Education for Builders and Developers in Charlotte, North Carolina
Authors: McSween Donald , McNeary John , Neumann F. Philip
Published: August 2022

In order to protect Charlotte's trees, we are at­tempting to educate builders, developers, and public agen­cies about tree values, physiology, protection, and planting. We feel that such education backed up by practical regulation will in the long run result in more real gains with less restric­tion on individual freedom.
Rots and Rods
Authors: Felix Robert , Shigo Alex
Published: August 2022

Trees with internal rot, or crotches likely to split, can be helped by proper bracing. Although the holes made for the bracing materials are wounds, and wounds start the processes that can lead to rot, the braces can extend the time that trees with rot and weak crotches can remain safe, attractive, and healthy. An understanding of how rots develop and how rods should be properly installed will help the ar­ borist to maximize the benefits of proper tree bracing and to minimize the injury caused by the new wounds required for the bracing materials. Some basic information on the develop­ ment of tree rots and installation of bracing materials is given.
Propagation of Quercus Seedlings in Bottomless Containers with Osmocote
Authors: Hathaway Robert , Whitcomb Carl
Published: August 2022

Shumard oak seedlings (Quercus shumardii) were grown in bottomless, square containers placed on a wire bench. The dominant tap root grew downward and was 'air pruned', producing a fibrous root system. Three heights of containers were cut from quart milk carton stock giving three volumes of media with the same surface area and three different drainage columns. Five rates of Osmocote 18·6·12, based on the surface area of the containers, were applied af­ter the seedlings had emerged. Growth increased significantly with the three highest levels of Osmocote. Seedlings grown in the smallest container were not significantly different from those in the larger containers. Five replications were planted in 2 gallon (7572 cm3) containers and grown for one year. Even though all seedlings were treated alike during this period, those which were propagated with higher fertility rates had an increased survival rate and faster growth suggesting that the nutritional state of liners, not necessarily age or size, strongly influences survival and future growth.
O DESEMPENHO DOS ESTUDANTES DE ENSINO MÉDIO DA REDE PÚBLICA É MELHOR EM CIDADES COM MAIOR PRESENÇA DO PROGRAMA BOLSA FAMÍLIA?
Authors: Araújo da Silva Douglas , Ferreira Monaliza de Oliveira , Pontes Lucas Andreza Daniela
Published: August 2022

O objetivo deste trabalho consiste em avaliar a relação entre Bolsa Família e o desempenho dos estudantes de ensino médio de escolas públicas, através de um banco de dados compreendido entre 2009 e 2016. A estimação do modelo constitui em um painel de efeito fixos, que analisa o impacto de variáveis que mudam ao longo do tempo. Os resultados evidenciam que renda, incidência do bolsa família, indicadores de educação e raça municipais são fatores importantes para o melhor desempenho dos jovens da rede pública municipal no Exame. À guisa de conclusão, recorre-se à necessidade de romper com o círculo vicioso da desigualdade, ampliando e adotando ações afirmativas que mantenham o estudante na escola, tais como Bolsa Família, ao mesmo tempo em que investimentos precisam se realizar na qualidade destas escolas.
Indicadores de eficiencias de las Instituciones Educativas Oficiales de Sampués – Sucre (Colombia), en la aplicación de la Ley 1014 de 2006 de Fomento a la Cultura del Emprendimiento
Authors:   Universidad Benito Juarez Garcia. Colombia, ALDANA Euris R.
Published: August 2022

El propósito investigativo fue determinar los indicadores de eficiencias de las Instituciones Educativas Oficiales de Sampués – Sucre, Colombia, en la aplicación de la Ley 1014 de 2006 fomento a la cultura del emprendimiento. Se empleó un estudio explicativo correlacional, método racional de análisis inductivo – deductivo, abordaje de investigación mixta. La conclusión principal, la ineficacia en los establecimientos educativos analizados ha sido la constante, con un nivel de insatisfacción en el cumplimiento de los objetivos de la mencionada Ley del 96.9
Absence of visitors during lockdown reveals natural variation in carbon dioxide level in the Glowworm Cave, Waitomo, New Zealand
Authors: Merritt David J , Hendy Chris , Corkill Shannon
Published: August 2022

Waitomo Glowworm Cave is a highly visited cave where the highlight is viewing the bioluminescence display of a large colony of glowworms. Anthropogenic carbon dioxide build-up in the cave is prevented by management of chimney-effect ventilation aided by a network of microclimate sensors. A cave door prevents ventilationunder drying conditions and promotes it when necessary to clear CO2 and when inflowing air has high relative humidity. A COVID-19-related nationwide “lockdown” in New Zealand from March 2020 resulted in neither staff nor visitors being present in the cave for 60 days, and provided an opportunity to assess the natural microclimate of the cave, especially the natural variation in partial pressure of carbon dioxide (pCO2). In addition, comparison to the previous year showed that the presence of people in the cave increased the cave temperatures but the effect was short-lived due to cave ventilation. During the period of lockdown, the daily increase of carbon dioxide partial pressure (pCO2) due to visitors was absent. When the cave door remained sealed, pCO2 varied and tended to lie at levels above that of the external atmosphere (410 ppm). Notably, rain events raised pCO2 by up to 200 ppm (v/v), which appeared to be sourced from both stream water and drip water. These natural CO2 sources rarely reached the levels associated with cave visitation. The results support current management practices that use door control to enhance cave ventilation when people are in the cave or when natural conditions (high stream levels and high drip-water levels) promote CO2 outgassing into the cave. Suppressing ventilation outside of those times reduces the risk of introducing dry air that could desiccate the glowworms.
PREVALÊNCIA DE TRAÇO FALCEMICO EM DOADORES DE SANGUE NA REGIÃO NORTE DO ESTADO DO RJ
Authors: Cardoso de Souza da Silva Delgado Larissa , Oliveira Sandra Chalhub de , Oliveira Cristiano Guilherme Alves de , Barreto Juliano Gomes
Published: August 2022

Introdução: Existe um grande número de hemoglobinas anormais, as quais compreendem um grupo de distúrbios hereditários que afetam os genes que codificam as cadeias globínicas alfa (α) e beta (β) da molécula de hemoglobina. Os portadores do traço falciforme são clínica e hematologicamente saudáveis, portanto aptos à doação de sangue. Objetivo: Avaliar a prevalência de traço falcemico em doadores de sangue na região Norte do Estado do Rio de Janeiro. Material e métodos: A metodologia empregada foi pesquisa com caráter exploratório de natureza retrospectiva baseada em informações do banco de dados do Hemocentro Regional de Campos dos Goytacazes/ RJ, abrangendo o período de 2004 à 2020. Resultados: Foram avaliados um total de 167.215 amostras de ambos os sexos, onde 4.992 amostras foram positivas, representando 2,99% para o traço falciforme (HbS), o que comparado com dados publicados de pesquisas em outras regiões do Brasil no mesmo período, observa-se que obtivemos na presente pesquisa valores que chegam ao dobro do percentual encontrado nas demais regiões brasileiras. Os resultados demostram um número considerável de doadores portadores de traço falcêmico, o que também reflete como o traço falcêmico encontra-se presente na população brasileira, demonstrando a importância da atenção nos serviços de hemoterapia, para as unidades de hemocomponentes oriundos de doadores portadores de traço falcêmico, no intuito de promover a sua adequada utilização transfusional. Conclusão: Através da presente pesquisa foi possível estimar a incidência de traço falcêmico em 2,99% da população de doadores do Hemocentro Regional de Campos – RJ, o que reflete uma realidade da Região Norte Fluminense. Tais fatos demonstram a importância da triagem hematológica na doação sanguínea, e a necessidade de orientação aos portadores de traço da Hbs com aconselhamento genético visando reduzir o risco nascimento de crianças portadoras de doença falciforme, onde estimase um elevado
DETERMINAÇÃO DE COMPOSTOS BIOATIVOS NAS PLANTAS AMAZÔNICAS CORAMINA (Pedilanthus tithymaloides (L.) Poit.) E MUSSAMBÊ (Tarenaya spinosa (Jacq.) Raf.)
Authors: Vieira Maria Raiane , Martins Jéssica de Lima , Oliveira Andrey Carlos do Sacramento de
Published: August 2022

Introdução: Coramina (Pedilanthus tithymaloides) e Mussambê (Tarenaya spinosa) são duas espécies vegetais que podem ser encontradas na (Tarenaya spinosa) são duas espécies vegetais que podem ser encontradas na região amazônica e são bastante utilizadas como plantas medicinais. No entanto, é evidente que o uso dessas plantas ocorre através do conhecimento empírico. Objetivo: Determinar a presença de compostos bioativos nos extratos das folhas dessas duas plantas coletadas na região metropolitana de Belém e no assentamento Santa Paula, pertencente ao município da cidade de Capitão Poço, interior do estado do Pará. Metodologia: Foi realizado análises para a determinação do teor de carotenoides totais e de antocianinas monoméricas, além da análise físico-química de pH. Resultados: Mostraram-se relevantes, devido à presença significativa de carotenoides totais nas amostras de Mussambê (7,3 e 12,2 µg/g) e principalmente nas amostras da coramina (19,1 e 35,1 µg/g). Além de apresentarem valores satisfatórios de antocianinas monoméricas, sendo o Mussambê com (0,66 e 0,74mg/g) e a Coramina com (1,46 e 0,66mg/g). Quanto ao pH as duas espécies apresentaram-se levemente ácidas com uma faixa de 5,3 a 5,78. Conclusão: Desse modo, o trabalho permitiu a comprovação de compostos bioativos nas duas espécies vegetais, pressupondo um provável potencial antioxidante.
Analisis Potensi RPP Education for Sustainable Development pada Mata Pelajaran Fisika SMA
Authors: Meda Tirtandro
Published: August 2022

Tujuan pembangunan berkelanjutan yang disetujui oleh para pemimpin global pada KTT Pembangunan Berkelanjutan Perserikatan Bangsa-Bangsa pada tahun 2015, menegaskan kembali kebutuhan kritis untuk menanamkan prinsip-prinsip ESD di semua tingkat pendidikan. Pendidikan diperkuat sebagai tujuan penting dalam pondasi 17 (SDGs) untuk membantu membangun masyarakat yang lebih berkelanjutan, adil, dan setara. Pendekatan penelitian yang digunakan dalam penelitian ini adalah kualitatif. Tujuan penelitian deskriptif kualitatif ini yaitu untuk mendeskripsikan kesesuaian perangkat pembelajaran mata pelajaran Fisika dengan semangat pendidikan untuk pembangunan berkelanjutan. Metode yang digunakan adalah deskriptif kualitatif menggunkan interpretasi data dari 30 RPP. Dari RPP yang dianalisis data yang didapatkan menunjukkan bahwa RPP yang dibuat dan digunakan tidak sesuai dengan yang diharapkan, yang menginginkan integrasi ke dalam pendidikan untuk pembangunan berkelanjutan. Lebih khusus lagi, kompetensi kesadaran diri masih minim dalam memfasilitasi siswa untuk dapat mencerminkan apa yang menjadi perannya dalam komunitas lokal dan masyarakat global. Berdasarkan hasil penelitian dapat disimpulkan bahwa tingkat kesesuaian RPP dengan prinsip-prinsip pendidikan untuk pengembangan berkelanjutan guru Fisika masih berkisar antara 13% hingga 70%. Indikator yang masih perlu banyak mendapat perhatian dari guru dalam merancang RPP adalah kompetensi kesadaran diri siswa.
Analysis of Saudi Arabia Intervention in Decisive Storm Operations in Yemen
Authors: Salim Fajri
Published: August 2022

This research analyses the factor that influenced Saudi Arabia's decision to intervene in Yemen's civil conflict through military intervention known as Operation Decisive Storm in 2015. Before 2014, Saudi Arabia always avoided intervening in Yemen's civil conflict. However, there was a behavioral change in Saudi Arabia's policy when they decided to do military intervention in Yemen. Answer this Explanatory research using strategic theory and qualitative research methods. In the analysis of this research, the researcher found that the reason why Saudi Arabia's sudden change to intervene the conflict is influenced by a geographical factor in which there is a potential threat from Houthi rebels to Saudi nearest region that directly borders Yemen and the participation of Saudi Arabia's Political Rival in Regions, Iran, for the battle of hegemony
Analisis Sentimen atas Wabah Penyakit Covid-19 di Indonesia dengan CrowdTangle di Media Sosial Facebook
Authors: Muhammad Fahreza Alfa Sina Mustof  , Ahmad R. Pratama
Published: August 2022

Organisasi Kesehatan Dunia (WHO) menyatakan COVID-19 pandemi di awal 2020, dan itu tiba di Indonesia pada Maret 2020. Tidak semua orang di dunia, termasuk Indonesia, memandang pandemi dalam cara yang sama. Menganalisis postingan Facebook Covid-19 adalah cara yang baik untuk mengukur opini publik tentang pandemi. Tujuan dari penelitian ini adalah untuk mengkaji sentimen publik di Indonesia terkait wabah penyakit Covid19 dengan menganalisis reaksi terhadap Postingan Facebook, terutama yang berasal dari yang terverifikasi rekening pemerintah, yang akan dibandingkan dengan akun dari portal berita. Dengan bantuan CrowdTangle, 1211 postingan Facebook yang berisi kata "wabah covid-19" dari 10 pemerintah pejabat dan 10 portal berita dikumpulkan antara 21 Januari 2020, dan 21 Januari 2021, untuk ini belajar. Boxplot dan visualisasi cloud kata, sebagai serta uji statistik, digunakan untuk mengkonfirmasi sentimen yang berbeda dalam posting oleh berbagai jenis akun, serta reaksi publik yang berbeda. Postingan dari pejabat pemerintah, di sisi lain, cenderung menjadi lebih positif, sedangkan posting dari portal berita cenderung lebih negatif. Selanjutnya, posting oleh pejabat pemerintah cenderung menerima lebih positif reaksi, terlepas dari sentimen mereka, dibandingkan dengan posting oleh portal berita, yang menerima berbagai reaksi publik tergantung pada sentimen.
Game Edukasi Interaktif Pengenalan Tata Surya Berbasis Animasi 2D untuk Siswa Kelas 6 SD
Authors: Nugraha Nur Budi
Published: August 2022

The solar system is one of the natural science lessons taught in grade 6 elementary school. This material is abstract because in studying it children cannot directly observe the phenomena of celestial bodies in the solar system. So far, only using books or 2D images as media. This study aims to create an educational game about the introduction of the solar system. 2D animation is made with icons and audio so that it can attract students' interest in learning and remembering solar system material. The result of the research is an educational game as an effective means of entertainment and learning. Students become interested in learning because of the application of the dissertation with attractive images and audio that helps increase enthusiasm for learning about the solar system. In testing the respondents as many as 22 people, the calculation results obtained as much as 59.1% strongly agree with this educational game
Ideas and perspectives: Allocation of carbon from net primary production in models is inconsistent with observations of the age of respired carbon
Authors: Sierra Carlos A. , Ceballos-Núñez Verónika , Hartmann Henrik , Herrera-Ramírez David , Metzler Holger
Published: August 2022

Abstract. Carbon allocation in vegetation is an important process in the terrestrial carbon cycle; it determines the fate of photoassimilates, and it has an impact on the time carbon spends in the terrestrial biosphere. Although previous studies have highlighted important conceptual issues in the definition and metrics used to assess carbon allocation, very little emphasis has been placed on the distinction between the allocation of carbon from gross primary production (GPP) and the allocation from net primary production (NPP). An important number of simulation models and conceptual frameworks are based on the concept that C is allocated from NPP, which implies that C is respired immediately after photosynthetic assimilation. However, empirical work that estimates the age of respired CO2 from vegetation tissue (foliage, stems, roots) shows that it may take from years to decades to respire previously produced photosynthates. The transit time distribution of carbon in vegetation and ecosystems, a metric that provides an estimate of the age of respired carbon, indicates that vegetation pools respire carbon of a wide range of ages, on timescales that are in conflict with the assumption that autotrophic respiration only consumes recently fixed carbon. In this contribution, we attempt to provide compelling evidence based on recent research on the age of respired carbon and the theory of timescales of carbon in ecosystems, with the aim to promote a change in the predominant paradigm implemented in ecosystem models where carbon allocation is based on NPP. In addition, we highlight some implications for understanding and modeling carbon dynamics in terrestrial ecosystems.
Impacts of estimated plume rise on PM2.5 exceedance prediction during extreme wildfire events: A comparison of three schemes (Briggs, Freitas, and Sofiev)
Authors: Li Yunyao , Tong Daniel , Ma Siqi , Freitas Saulo R. , Ahmadov Ravan , Sofiev Mikhail , Zhang Xiaoyang , Kondragunta Shobha , Kahn Ralph , Tang Youhua , Baker Barry , Campbell Patrick , Saylor Rick , Grell Georg , Li Fangjun
Published: August 2022

Abstract. Plume height plays a vital role in wildfire smoke dispersion and the subsequent effects on air quality and human health. In this study, we assess the impact of different plume rise schemes on predicting the dispersion of wildfire air pollution, and the exceedances of the National Ambient Air Quality Standards (NAAQS) for fine particulate matter (PM2.5) during the 2020 Western United States Wildfire season. Three widely used plume rise schemes (Briggs 1969, Freitas 2007, Sofiev 2012) are compared within the Community Multiscale Air Quality (CMAQ) modelling framework. The plume heights simulated by these schemes are comparable to the aerosol height observed by the Multi-angle Imaging SpectroRadiometer (MISR). The performance of the simulations with these schemes varies by fire case and weather conditions. On average, simulations with higher plume injection heights predict lower AOD and surface PM2.5 concentrations near the source region but higher AOD and PM2.5 in downwind regions due to the faster spread of the smoke plume once ejected. The two-month mean AOD difference caused by different plume rise schemes is approximately 20–30 % near the source regions and 5–10 % in the downwind regions. Thick smoke blocks sunlight and suppresses photochemical reactions in areas with high AOD. The surface PM2.5 difference reaches 70 % on the west coast and the difference is lower than 15 % in the downwind regions. Moreover, the plume injection height affects pollution exceedance (>35 μg/m3) forecasts. Higher plume heights generally produce larger downwind PM2.5 exceedance areas. The PM2.5 exceedance areas predicted by the three schemes largely overlap, suggesting that all schemes perform similarly during large wildfire events when the predicted concentrations are well above the exceedance threshold. At the edges of the smoke plumes, however, there are noticeable differences in the PM2.5 concentration and predicted PM2.5 exceedance region. This disagreement among the PM2.5 exceedance forecasts may affect key decision-making regarding early warning of extreme air pollution episodes at local levels during large wildfire events.
Electroplated waveguides to enhance DNP and EPR spectra of silicon and diamond particles
Authors: Himmler Aaron , Albannay Mohammed M. , von Witte Gevin , Kozerke Sebastian , Ernst Matthias
Published: August 2022

Abstract. Electroplating the waveguide of a 7 T polarizer in a simple innovative way increased microwave power delivered to the sample by 3.1 dB. Silicon particles, while interesting for hyperpolarized MRI applications, are challenging to polarize due to inefficient microwave multipliers at the electron Lamour frequency at high magnetic fields and fast electronic relaxation times. Improving microwave transmission directly translates to significantly higher EPR signal at high-field, low-temperature conditions and promises faster and higher 29Si polarization build-up through DNP.
Supervised models to predict the Stunting in East Aceh
Authors: Darnila Eva , Maryana Maryana , Mawardi Khalid , Sinambela Marzuki , Pahendra Iwan
Published: August 2022

Nowadays, Undernutrition is the main cause of child death in developing countries. There are many people and organizations try to mitigate or minimize case of child death. Thus, this paper aimed to has excellent method to handle undernutrition case by exploring the efficacy of machine learning (ML) approaches to predict Stunting in East Aceh administrative zones of Indonesia and to identify the most important predictors. The study employed ML techniques using retrospective cross-sectional survey data from East Aceh, a national-representative data is collected from government by using 2019 about stunting data. We explored Random forest commonly used ML algorithms. Random Forest (RF) as an extension of bagging that in addition for taking random sample of data and also uses random subset of features which mitigates over fitting. Our results showed that the considered machine learning classification algorithms by random forest can effectively predict the stunting status in East Aceh administrative zones. Persistent stunting status was found in the east part of Aceh. The identification of high-risk zones can provide more useful information and data to decision-makers for trying to reduce child undernutrition.