bluuebunny/crossref_metadata_2025 huggingface dataset:
Drug-Induced Diseases in Cardiology
Authors: Мацкевич С.А. , Кожанова И.Н.
Published: April 2024

На сегодняшний день становится весьма актуальной проблема осложнений лекарственной терапии с развитием лекарственно-индуцированных заболеваний. Это обусловлено назначением схем лечения при некоторых заболеваниях на длительный период, а также внедрением в медицинскую практику большого числа лекарственных препаратов, обладающих кардиотоксичностью. В статье приведены данные о наиболее частых лекарственно-индуцированных заболеваниях в кардиологии. Рассмотрены основные механизмы развития кардиотоксичности лекарственных препаратов, факторы риска. Кардиотоксичность представляет собой медицинскую и социально-экономическую проблему, поскольку ослабляет эффективность и безопасность проводимой фармакотерапии, ухудшает прогноз основного заболевания.

The problem of complications of drug therapy with the development of drug-induced diseases is becoming very relevant today. This is due to the prescription of long-time treatment regimens for certain diseases, as well as the introduction into medical practice of a large number of cardiotoxic drugs. The article provides data on the most common drug-induced diseases in cardiology. The main mechanisms of development of cardiotoxicity of drugs and risk factors are considered. Cardiotoxicity is a medical and socio-economic problem, since it weakens the effectiveness and safety of pharmacotherapy and worsens the prognosis of the underlying disease.
Necessity and Modern Possibilities for Assessing the Body’s Availability of Potassium
Authors: Якубова Л.В. , Мисюк Л.Ф. , Егорченко Н.П.
Published: April 2024

В статье представлен обзор литературы по обеспеченности калием населения Республики Беларусь и других стран. Приведен перечень состояний и заболеваний, при которых стоит оценивать уровень калия в крови. В настоящее время оценка уровня калия выполняется в биохимических анализах крови поликлиник г. Гродно в 21,4–22,3% исследований. В статье представлен опросник для неинвазивной оценки содержания калия в организме, который может широко использоваться врачами в практическом здравоохранении.

The article presents a review of the literature on the availability of potassium to the population of the Republic of Belarus and other countries. A list of conditions and diseases in which it is worth assessing the level of potassium in the blood is given. Currently, the assessment of the level of potassium is performed in biochemical blood tests of polyclinics in Grodno in 21.4–22.3% of studies. The article presents a questionnaire for a non-invasive assessment of the content of potassium in the body, which can be widely used by doctors in practical healthcare.
Features of Hypoglycemic Pharmacotherapy of Gestational Diabetes Mellitus
Authors: Чак Т.А. , Высоцкая Ю.В. , Романова И.С. , Кожанова И.Н.
Published: April 2024

Гестационный сахарный диабет (ГСД) – это заболевание, от которого страдает все большее число беременных женщин во всем мире. Опасность гипергликемии во время беременности заключается не только в многочисленных перинатальных осложнениях, но и в долгосрочных последствиях, влияющих на здоровье матери и развитие плода. Потребность в фармакологическом лечении возникает у 15–30% пациентов с ГСД, а 70–85% пациентов с ГСД можно вести с помощью модификации диеты, изменения образа жизни, физической активности и мониторинга уровня глюкозы в крови. Согласно многочисленным клиническим исследованиям, применяемая в настоящее время фармакотерапия ГСД является достаточно безопасной. В Республике Беларусь в качестве медикаментозной терапии ГСД рекомендован к использованию только инсулин. В некоторых странах помимо инсулинотерапии для лечения ГСД могут применяться метформин или отдельные препараты группы сульфонилмочевины. В статье представлен обзор рекомендаций и клинических исследований гипогликемических препаратов у беременных женщин.

Gestational diabetes mellitus (GDM) is a condition that affects increasing number of pregnant women worldwide. The danger of hyperglycemia during pregnancy lies both in numerous perinatal complications and has long-term consequences affecting the health of the mother and the development of the fetus. 15–30% of patients with GSD need pharmacological treatment, and 70–85% of patients with GSD can be managed using diet modification, lifestyle changes, physical activity and blood glucose monitoring. The GDM pharmacotherapy used so far is acceptably safe according to numerous clinical studies. Only insulin is recommended for use as a drug therapy for GSD in the Republic of Belarus. Metformin or some sulfonylurea drugs can be used for the treatment of GSD in addition to insulin therapy in some countries. The article provides an overview of some recommendations and clinical studies of hypoglycemic drugs in pregnant women.
Clinical and Pharmacological Characteristics of Glucocorticoids (Pulse Therapy in Patients with Multiple Sclerosis)
Authors: Романова И.С. , Матюшко Т.С. , Кожанова И.Н. , Чак Т.А. , Кардаш О.Ф. , Еленская С.В.
Published: April 2024

В статье представлена клинико-фармакологическая характеристика глюкокортикоидов – одной из востребованных групп лекарственных препаратов в клинической практике лечения как хронических аутоиммунных заболеваний, так и неотложных состояний. Уделено внимание тактике применения глюкокортикоидов у пациентов с рассеянным склерозом.

The clinical and pharmacological characteristics of glucocorticoids, one of the most popular groups of drugs in clinical practice for the treatment of both chronic autoimmune diseases and emergency conditions, are presented. Attention is paid to the tactics of using glucocorticoids in patients with multiple sclerosis.
Emergencias asociadas a la paratiroides: una revisión narrativa
Authors: Miño Bernal Jorge Fernando , Serna Trejos Juan Santiago , Bermúdez Moyano Stefanya Geraldine , Gómez Martinez Brian  José , Prado Molina Diego Gerardo
Published: April 2024

La atención médica de urgencia relacionada con la glándula paratiroidea abarca una amplia gama de enfermedades, cuyo denominador común son los trastornos del metabolismo del calcio. La glándula paratiroides desempeña un papel fundamental en la regulación de los niveles de calcio en el cuerpo y cualquier disfunción de esta pequeña glándula puede tener un impacto significativo en la homeostasis del calcio y, por lo tanto, en la salud ósea. Una de las afecciones más comunes asociadas con la glándula paratiroidea es el hipoparatiroidismo. Esta enfermedad se caracteriza por una disminución de la producción de hormona paratiroidea, lo que conduce a niveles anormalmente bajos de calcio en la sangre. El hipoparatiroidismo puede tener presentaciones clínicas variadas y complejas, con síntomas que van desde convulsiones hasta problemas dermatológicos como la psoriasis, pasando por complicaciones cardíacas y neuromusculares como arritmias, laringoespasmos, cataratas, papiledema, tetania y miopatías, entre otras. El conocimiento de estos trastornos es necesario para brindar una atención médica eficaz y mejorar la calidad de vida de los pacientes enfermos. Por tanto, es necesario aclarar que las emergencias paratiroideas representan una amplia gama de trastornos que afectan la homeostasis del calcio y la salud ósea, de los cuales el hipoparatiroidismo es un excelente ejemplo. El tratamiento de estos trastornos varía según la causa y la gravedad, y su conocimiento es esencial para los médicos de diversas especialidades y entornos clínicos, ya que su impacto se extiende a áreas críticas de la atención sanitaria
Adaptación y validación de cuestionario para medir competencias digitales docentes
Authors: Rodríguez-Rivas José , Muñoz-Solís Erika
Published: April 2024

Las competencias digitales en los docentes se han vuelto imprescindibles en las instituciones de educación superior, sobre todo después de la situación originada por la pandemia de COVID-19. Las Instituciones de Educación Superior (IES) deben asegurarse de que los docentes manejen bien sus competencias digitales (CD). En este estudio se tuvo como objetivo la adaptación y validación del Marco de Competencias Digitales para la Ciudadanía DigComp 2.2 para conocer el nivel de las CD en docentes de una IES. En la prueba piloto participaron 34 docentes y se realizó bajo un enfoque cuantitativo de tipo descriptivo con un diseño de tipo instrumental, no experimental de corte transversal. Para el análisis de los datos se utilizó el software estadístico SPSS y para realizar la validación del contenido del instrumento se trabajó en el juicio de expertos. Para verificar la confiabilidad se utilizó el estadístico alfa de Cronbach obteniéndose un valor de un .987 lo que indica una confiabilidad excelente. Adicionalmente, se sometió al análisis de fiabilidad si se elimina un elemento y en todos los ítems se alcanzaron valores por encima de .900 en el alfa de Cronbach, lo que evita tener que suprimir ítems del instrumento. Los resultados obtenidos permiten contar con un instrumento confiable para su posterior aplicación y análisis.
Radikal Sürdürülebilirlik Perspektifinden Kamusal Alan ve Umut
Authors: Bengü Devran
Published: April 2024

Sürdürülebilir kalkınmanın her üç boyutunun da uzun vadede etkili sonuçlar vermesi için radikal yaklaşımlarla bütüncül olarak planlanması gerektiği fikri bu çalışmanın omurgasını oluşturmaktadır. Böyle bir kalkınma yaklaşımı demokrasinin varlığını ve işleyişini gerektirir. Demokrasi temelli bir perspektiften bakıldığında, kamusal alanın canlılığı ve sürekliliği sürdürülebilir kalkınmanın toplumsal boyutunda temel ilkelerdir. Kamusal alan kuramcıları Arendt, Habermas, Negt ve Kluge'nin çalışmalarından yararlanılmıştır. Umudun varlığı sürdürülebilir yaşamın her boyutu için gereklidir. Eğitim bilimlerinde sürdürülebilirlik pedagojisi üzerine yapılan çalışmalar, umut pedagojilerinin sürdürülebilirlik kavramının temel değerlerinin özümsenmesinde etkili olduğunu ortaya koymuştur. Sürdürülebilirlik pedagojisi bağlamında etkili olduğu vurgulanan 'umut' olgusunun kamusal alanın sürdürülmesinde de önemli ve gerekli olduğu kuramsal çerçevede ortaya konulabilir. Kavramlar arasındaki ilişkileri tespit etmek ve bir teori oluşturmak için felsefe, siyaset felsefesi ve eğitim bilimleri disiplinlerinde bir literatür araştırması yapılmıştır. Kavramlar arasında umut olgusu üzerinden kurulan korelasyon, kamusal alanın sürdürülebilirlik pedagojisi için etkili bir araç olduğuna dikkat çekmektedir. Benzer şekilde, umut pedagojilerinin yaygınlaştırılmasının da kamusal alanın canlılığının sürdürülmesinde etkili bir yaklaşım olacağı öngörülebilir. Bu etkileri dikkate alan strateji ve planlar radikal sürdürülebilirlik yaklaşımlarını güçlendirecektir. Bu çalışma, uzun soluklu sürdürülebilir kalkınmaya yönelik yöntemlerin geliştirilmesi için teorik bir temel sağlamaktadır.
Assessment of Performance and Emission Characteristics of Biodiesel/Graphene/ N-Octanal Blends in Water Cooled Compression Ignition Engine
Authors:   Associate Professor & Faculty by Research in Department of Mechanical Engineering, Sasi Institute of Technology and Engineering, Tadepalligudem (A.P.), India., Billa Dr. Kiran Kumar , Prasad P.H.V.Siva ,   UG Student, Department of Mechanical Engineering, Sasi Institute of Technology and Engineering, Tadepalligudem (A.P.), India., Satyasai M.D.V. ,   UG Student, Department of Mechanical Engineering, Sasi Institute of Technology and Engineering, Tadepalligudem (A.P.), India., Aditya K.K.V.V. Krishna ,   UG Student, Department of Mechanical Engineering, Sasi Institute of Technology and Engineering, Tadepalligudem (A.P.), India.
Published: April 2024

Biodiesel and alcohols are only two of the numerous alternative fuels that have found widespread commercialization in the transportation and industrial sectors. Cottonseed oil and n-octanol piqued our curiosity again in this regard. The engines used in the experiments are single-cylinder four-stroke diesel engines with a power output of 1.5 kW. The tests are run at 1500 rpm with varying loads on the diesel, cottonseed oil, and graphene mixtures. i.e., BB1(Diesel 75%+ Cottonseed biodiesel 20%+ n-Octanol 5%), BB2(Diesel 75%+ Cottonseed biodiesel 20%+ n-Octanol 5%+ nanographene 25ppm), BB3(Diesel 75%+ Cottonseed biodiesel 20%+ n-Octanol 5%+nanographene 50ppm), BB4(Diesel 70%+ Cottonseed biodiesel 20%+ n-Octanol 10%), BB5(Diesel 70%+ Cottonseed biodiesel 20%+ n-Octanol 10%+ nanographene 25 ppm), BB1(Diesel 70%+ Cottonseed biodiesel 20%+ n-Octanol 10%+ nanographene 50ppm). The findings indicate that incorporating cottonseed oil leads to an improvement in brake thermal efficiency, along with a decrease in specific fuel consumption and exhaust gas temperature. By increasing the amount of cottonseed oil in the blend, the emission parameters such as CO, CO2, NOx, and O2 are reduced, while HC emissions increase. Adding n-octanol and graphene to the cottonseed oil blend diesel fuel has a comparable impact to adding pure cottonseed oil in different proportions. This leads to an increase in brake thermal efficiency, a decrease in specific fuel consumption, and a reduction in exhaust gas temperature.
Un valore locale di ormai
Authors: Mazzoleni Marco
Published: April 2024

Due lettrici ci scrivono da Bologna per chiedere se l’uso di ormai in espressioni come “ormai cadevo!” per “stavo per cadere, sono quasi caduto” appartenga all’italiano comune oppure si debba considerare un regionalismo.
HUBUNGAN ANTARA AKTIVITAS FISIK DAN TINGKAT STRES DENGAN RESTING HEART RATE PADA MAHASISWA KEDOKTERAN
Authors: Syeftiani Nabilatussalma , Citrawati Mila , Safira Lisa , Kristanti Melly
Published: April 2024

Resting Heart Rate (RHR) atau denyut jantung istirahat merupakan salah satu indikator penilaian risiko penyakit kardiovaskular. Rendahnya aktivitas fisik dan tingginya tingkat stres pada mahasiswa kedokteran dapat meningkatkan RHR yang akan meningkatkan risiko penyakit kardiovaskular dan menurunkan harapan hidup. Tujuan penelitian ini untuk mengetahui hubungan antara aktivitas fisik dan tingkat stres dengan RHR pada mahasiswa Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta tahun 2022. Jenis penelitian ini termasuk analitik observasional dengan desain cross-sectional pada 46 orang subjek yang dipilih menggunakan teknik proportional stratified random sampling. Pengambilan data RHR dilakukan secara langsung, sedangkan data aktivitas fisik dan tingkat stres menggunakan kuesioner GPAQ dan MSSQ. Analisis data meliputi analisis univariat dan bivariat menggunakan uji Chi-Square. Aktivitas fisik responden paling banyak pada kategori sedang, tingkat stres pada kategori berat, dan RHR pada kategori tinggi. Uji bivariat menunjukkan tidak terdapat hubungan bermakna antara aktivitas fisik dengan RHR (p = 0,665) dan antara stres dengan RHR (p = 0,226). Mahasiswa terbiasa melakukan aktivitas fisik harian dan menghadapi stresor selama menjalani perkuliahan. Terdapat kecenderungan RHR normal pada mahasiswa dengan aktivitas fisik sedang sampai tinggi, sedangkan pada mahasiswa dengan stres berat cenderung memiliki RHR tinggi.
Kata kunci : aktivitas fisik, denyut jantung istirahat, stres
GAMBARAN HISTOPATOLOGI GINJAL MENCIT (Mus musculus) GALUR DDY PADA UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN SALAM
(Syzygium polyanthum)
Authors: Kristiana Ris , Fathya Nurul Aida , Abbas Endah Hamidah , Juliastuti Henny , Linasari Desy , Rachmawati Rika
Published: April 2024

Penggunaan obat-obatan yang berasal dari bahan alam, tetap dibutuhkan suatu uji untuk mengetahui tingkat keamanannya. Tingkat keamanan zat tertentu dapat diamati dari efek toksik yang ditimbulkan pada berbagai organ, salah satunya pada ginjal yang berperan penting dalam sistem ekskresi melalui uji praklinik. Daun salam (Syzygium polyanthum) merupakan salah satu tanaman obat yang sering digunakan oleh masyarakat Indonesia. Tujuan penelitian ini untuk mengetahui adanya perubahan histopatologi ginjal mencit jantan dan betina pada pemberian akut ekstrak etanol daun salam (EEDS). Penelitian ini merupakan penelitian observasional mengenai histopatologi ginjal mencit (Mus musculus) putih jantan dan betina galur DDY. Sediaan berjumlah 48 buah, yang terbagi menjadi empat kelompok, yaitu kelompok kontrol negatif (K), kelompok perlakuan yang diberikan ekstrak etanol daun salam dosis 1250 mg/kgBB (P1), dosis 2500 mg/kgBB (P2), dan dosis 5000 mg/kgBB (P3). Sampel organ ginjal dibuat preparat histopatologi dengan metode pewarnaan HE, lalu dilakukan pemeriksaan histopatologi. Gambaran histopatologi yang diamati berupa inflamasi, degenerasi lemak, dan nekrosis pada ginjal serta data dianalisis dengan uji Kruskal-Wallis. Hasil penelitian ini menunjukkan bahwa pemberian ekstrak etanol daun salam dosis 1250 mg/kgBB, 2500 mg/kgBB, dan 5000 mg/kgBB pada mencit jantan dan betina tidak mengakibatkan perubahan bermakna terhadap gambaran histopatologi ginjal. Efek toksik dapat timbul apabila suatu zat telah mencapai organ target dengan konsentrasi cukup tinggi dan waktu yang cukup untuk menimbulkan efek tersebut. Walaupun menunjukkan tidak adanya toksisitas, namun tetap dibutuhkan uji klinis lebih lanjut untuk mengkonfirmasi keamanan daun salam sebagai fitofarmaka.

Kata kunci: daun salam, histopatologi ginjal, uji toksisitas akut
Beetles (Coleoptera) associated with the tinder fungus, Fomes fomentarius (L.) Fr. (Polyporales: Polyporaceae) in Ukraine
Authors: Drogvalenko O. M.
Published: April 2024

The tinder fungus Fomes fomentarius is one of the most common species of xylotrophic fungi, found both in natural and anthropogenic biotopes. The fungi have perennial fruiting bodies with dense but not very hard textured ‘tissues’ and are the center of a stable complex of mycetophilous insects, mainly beetles. A study in Ukraine found 110 species of beetles from 26 families on/in carpophores, of which 72 species turned out to be mycetobionts. It was found that, regardless of the location of the study, the specialist species complex remains constant: Tenebrionidae — Ciidae (Cis spp. from the castaneus species group) — Ciidae (Ropalodontus spp.) — Ptinidae (Dorcatoma spp.). 2 figs, 1 tab., 23 refs.
A DESCRIPTIVE STUDY TO ASSESS THE KNOWLEDGE OF NEONATAL CONVULSIONS AMONG NURSING STUDENTS AT NARAYAN NURSING COLLEGE, JAMUHAR SASARAM.
Authors: Umar Mohammed , Kumari Sanjana , Nagpal Nitika , Tripathi Ruchi , Ghosh Kiran , Maithani Tanuj , Ahmed Afzal , Kumar Dipu
Published: April 2024

Neonatal convulsions are a commonly encountered neurological condition accounting for 1/3rd death of the neonates. Adescriptive research study
was conducted among the 60 purposefully selected Nursing students after getting informed consent on the knowledge of neonatal convulsion using
a self-instructional questionnaire. The data was collected and analysed using statistical software and the results showed that out of 60 participants,
35 (58.3%) had average knowledge and 25(41.7%) had adequate knowledge. In nding the association between the knowledge and selected
demographic variables there was a signicant association between gender and residence. The study reveals that though the students have adequate
knowledge of neonatal convulsion, the care rendered to the child during the neonatal period by the students must be focused on helping the country
as laid by the current Indian government focusing on sustainable tomorrow.
ROLE OF ULTRASONOGRAPHIC ASSESSMENT OF INTERNAL JUGULAR VEIN DISTENSIBILITY IN THE PREDICTION OF HYPOTENSION FOLLOWING SPINAL ANAESTHESIA: AN OBSERVATIONAL STUDY
Authors: Bhonsle Kaushal , Dalal Kajal , Bhirud Pritee
Published: April 2024

Background: Postspinal anesthesia hypotension (PSH) is a common side effect caused by the reduction of systemic vascular resistance. To
prevent this, pre/co-loading of intravenous uids is usually done. Many studies have used IVC measurements for predicting uid response but few
studies have examined whether measurements of the IJV can predict PSH. Hence, we hypothesized that the right IJV distensibility index measured
after preloading using ultrasonography may help to predict PSH. Methods: Patients between 18 -65 years, ASA grade I & II who underwent
elective infraumbilical surgeries under spinal anaesthesia, were preloaded with IV Ringer Lactate at 10ml/kg over 10 mins. USG examination of
IJV was performed before & after preloading. After spinal anesthesia, changes in blood pressure were noted for 30 mins. SBP drop below
100mmHg or 25% decrease of SBP from the baseline value was considered signicant. Retrospectively the patients were divided into hypotensive
and non-hypotensive groups. Out of 61 patients, 39 patients (63.9%) developed PSH. The two groups w Results: ere similar in all baseline
characteristics (p>0.05). Receiver operating characteristic curve (ROC) analysis showed that the right IJV distensibility index had a sensitivity of
94.87% and a specicity of 50.00% to predict the PSH at a cut-off point of 16.5% below which hypotension was seen. Area under curve (AUC) was
0.768. Right IJV distensibility index, was found to be signicant in predicting incidence of PSH u Conclusion: pto 30 mins of anaesthesia. IJV
distensibility index with a cutoff value of 16.5% can be considered as a predictor of PSH.
ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF AEGLE MARMELOS (L.) CORRȆAALONE AND IN COMBINATION WITH PHENYTOIN BY MAXIMAL ELECTROSHOCK INDUCED SEIZURE (MES) IN ALBINO MICE.
Authors: Sobina Moirangthem , Tarinita Devi Leishangthem , Meena Devi Nameirakpam , Dhanachandra Singh Ashem , Devi M. Medhabati
Published: April 2024

Aim: To evaluate the anticonvulsant activity of ethanolic extract of Aegle marmelos (L.) correa alone and in combination with phenytoin by
maximal electroshock (MES) induced seizure in albino mice. Method: Ethanolic extract of Aegle marmelos (L.) correa (EEAM) was prepared
using Soxhlet apparatus. The anticonvulsant activity of 2 doses of EEAM (200mg/kg and 400mg/kg), standard drug phenytoin (therapeutic dose
20mg/kg, sub therapeutic dose 10mg/kg), combination of EEAM (200mg) and phenytoin (10mg/kg) and combination of EEAM (400mg/kg) and
phenytoin 10mg/kg were evaluated by maximal electroshock induced seizure (MES) model. After 1hr of oral administration of the test drug and
standard drug, the pre-screened albino mice were subjected to MES seizures by electroconvulsiometer with a current of 45mA for 0.2 sec via
transauricular electrodes. Duration of Tonic hind limb extension (THLE) was recorded and percentage protection calculated. Results: EEAM
exhibited signicant anticonvulsant activity in the MES model at doses 200mg/kg and 400mg/kg and also in combination with phenytoin
subtherapeutic dose (10mg/kg) when compared with control group (p< 0.001). Combination of EEAM 400mg/kg and sub therapeutic dose of
phenytoin 10mg/kg exhibited similar anticonvulsant effect when compared with standard therapeutic dose of phenytoin. Conclusion: EEAM
exhibited signicant anticonvulsant activity when given alone and it also potentiates the anticonvulsant activity of sub therapeutic dose of
phenytoin when given in combination in the MES model.
A CROSS-SECTIONAL STUDY TO INVESTIGATE WORKPLACE ANXIETY AND CORONAPHOBIAAMONG SARS-COV2 FRONT-LINE WORKERS IN A TERTIARY CARE HOSPITAL
Authors: Misra Anushka , Khan Gooty Mohammad Zahed , Niranjan Punit Gopal , Kolathingal Biniyam
Published: April 2024

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was responsible for the recent coronavirus pandemic. Although a
great deal of attention has been focused on the development of vaccines and how the healthcare system is managing and coping with the pandemic,
very little attention has been directed towards how healthcare workers are coping with the same. The term Coronaphobia can be dened as an
excessively triggered response of fear of contracting the virus causing COVID-19. Workplace anxiety has already been a problem in primary
healthcare, but with the current pandemic and frontline healthcare workers being affected directly, this demands further study to assess the same
during these unprecedented times. Methodology This was a cross-sectional study done on 134 front-line workers (consulting physicians, staff
nurses, interns and post-graduates) who had been posted on duty from March 2021 to September 2021 during the second wave of the COVID-19
pandemic. Data was collected via an online survey. Informed consent was taken before including them in the study. The Workplace Phobia Scale
(WPS) and the Fear of COVID-19 Scale (FCV-19S) were the main psychometric instruments used in this study. In addition, a semi-structured
questionnaire was devised to obtain socio-demographic details of all the participants. Results Workplace anxiety was assessed using the
Workplace Phobia Scale (WPS). Mean scores ranged from 1.56 (7th item) to 3.92 (10th item) whereas standard deviation ranged from 1.03 (2nd
item) to 1.49 (4th item). Coronaphobia was not observed among the majority of respondents with an overall neutral attitude towards the items in the
questionnaire. ConclusionsThis study highlighted that frontline workers working in a pandemic have the propensity to develop workplace anxiety
symptoms. Although they did not exhibit symptoms of Coronaphobia, this could be attributed to a higher level of knowledge and better preventive
measures employed by healthcare workers.
An evaluation of the microbiological quality of commercial beef Suya sold in Benin city, South south of Nigeria
Authors: Ebabhamiegbebho P.A. , Abel E.S. , Solomon Clementina
Published: April 2024

The safety of suya a ready to eat barbecue meat for consumption has been of growing concern as a result of the handling practices associated with its processing . Of major concern is the microbiological quality of the product. This study evaluate d the microbial content of suya meat processed and consumed in Benin City , Edo State, Nigeria . A total of nine (9) suya meat samples were purchased from popular suya spots within each of the three Loc al Government Areas of Benin City, namely: Ikpoba Okha, Egor and Oredo. Samples were subjected to microbiological analysis by first evaluating for the Total Heterotrophic Bacterial Count (THB C)C), Mean Bacterial Count (MBC) MBC), Total Heterotrophic Fungal Count (THFC) and Mean Fungal Count (MFC) followed by characterization and identification of the organisms present and t he n the sensitivity of the bacteria to some antibiotic s . Results showed that highest THB C cfu / and THFC ( cfu / w ere recorded in suya obtained from Aduwawa of Ikpoba Okha L ocal G overnment A rea as 6.14 x 10 ⁴ and 2.24 x 10 ⁴ , respectively ; with lowest values recorded in samples from Ring road of Oredo LGA as 1.83 ×10 ⁴ and 0.66 x 10 4 , respectively . MBC values cfu / ranged from 3.29 x 10 ⁴ to 4.37 x 10 ⁴ while MFC values were in the range of 1.19 x 10 ⁴ to 1.58 x 10 ⁴ . Bacterial species detected in suya sample s were Proteus sp, Micrococcus sp, Serrattia sp, Bacillus sp, Escherichia coli, Klebsella sp, and Pseudomonas sp while fungi isolates detected were Aspergillus niger, Fusarium sp, Saccharomyces sp, Penicillium sp , Aspergillus sp and Penicillium sp The bacteria and fungi isolates with the highest distribution were Bacillus sp, and Penicillum sp , while Escherichia coli and Aspergillus sp, were least distributed in the study. The bacteria with the highest susceptibility was Escherichia coli while Pseudomonas auruginosa was the least susceptible to the antibiotic discs.
Analysis of credit demand and supply markets among youth farmers in Agro-ecological zone B, Kogi State, Nigeria
Authors: Adejo P.E , Olowogbayi J. A. , Akubo C.
Published: April 2024

There has been a shift of dominance in the sources of credit markets in Nigeria from the Government to the private sector. Inadequacy of capital has been identified as one of the constraints faced by youth farmers. This research work aimed to analyse credit demand and supply markets among youth farmers. Data collected were analyzed using descriptive, multiple regression and Z-test. Most credits were sourced through informal souces by the youth farmers. Personal savings(65%), RoSCAs (52.5%) and Money lender(50.8%) respectively are from the informal sources while LAPO (42%) and even commercial bank (15%) which is the least are obtained from formal sources. Further, the study showed that 50% of the respondents demanded credit to the tune of N2, 000,000 while most of the credit supplied(45.83%) was only less than N100.000. The multiple regression results showed an R2 value of 0.65. The study identified the potential credit demanded by the farmers to be at the range of N1, 000,001-2,000,000. Furthermore, the study identified age, marital status, level of education, interest rate and credit awareness as the major determinants of the volume of actual credit supplied by youth farmers. The test for significant difference shows that there is significant difference in the amount of credit sourced and required by the youth farmers by 1%. The study recommends that the interest rate charged on credit facilities should be reduced to motivate the youth farming in the study area to source for credit
Mineral balance, nutrient intake and digestibility of West African dwarf (Wad) goats fed urea-mixed milled maize stover diets
Authors: Okeniyi F. A. , Olawoye S.O. , Animashahun R. A , Alabi O.O. , Shoyombo A. J. , Falana M.B. , Aina A. B. J , Onwuka C. F. I. , Sowande O. S
Published: April 2024

Twelve (12) male West African dwarf (WAD)goats with an average weight of 8.5 kg were monitored in a completely randomized design, to determine the nutrient intake, digestibility and mineral balance when fed urea-mixed milled maize stover (UMMS) diets in the dry season. Four dietsD1, D2, D3 and D4 containing 0, 3, 4.5 and 6% inclusion levels of urea respectively and 60% maize stovers each were fed to the goats during 14 weeks feeding experiment, for digestibility trials, weighed feed was fed each day for 7 days after an initial 14 day adaptation period, urine, faecal and diet samples were collected and analysed. Results showed that crude protein (CP) content of diets increased as the inclusion level of urea increases while voluntary dry matter intake (DMI) of all nutrients by bucks, decreased significantly (P<0.05) with the increase in dietary urea. There were significant differences (P<0.05) in the apparent digestibility of crude fibre (CF) and nitrogen free extract (NFE) of diets but all other nutrients showed no significant variation (P>0.05) in digestibility. Mineral intake by bucks decreased significantly (P<0.05) with increasing level of dietary urea inclusion. The highest value of mineral retention was recorded for goats on diet D1. The inadequacy of some minerals in experimental diets may require supplementation when a urea-mixed milled maize stover (UMMS) diet is fed to goats during the dry season.
The effect of graded levels of bovine blood meal on growth performance, haematology and cost benefit of broiler chickens
Authors: Ekwe O.O. , Nwali C.C, , Nwonu S.R. , Mgbabu C.N. , Ude I.U.
Published: April 2024

A study was conducted to evaluate the effect of graded levels of bovine blood meal diets on the growth performance, haematology and cost-benefit of broiler chickens production. A total of sixty broiler chickens of 4 weeks old were used in a 28 days feeding trial. The birds were randomly allotted to four treatments (T1, T2, T3 and T4) in a Completely Randomized Design (CRD). Each treatment was replicated three times and each replicate had five birds. T1 (Control) contained 0% bovine blood meal. T2, T3 and T4 contained 5%, 10% and 15% bovine blood meal, respectively. The data such as feed intake, weight gain, feed conversion ratio, daily protein intake and protein efficiency ratio were generated. The haematological indices such as haemoglobin counts, packed cell volume, red blood cell, white blood cell, neutrophils, lymphocytes, monocyte and eosinophil were evaluated. The feed cost - benefit analysis was performed on the following: feed cost/kg weight gain, total cost of production and net returns. All the data generated were subjected to statistical analysis using One-Way Analysis of Variance (ANOVA). Mean values were separated using Least Significant Difference (LSD). Results showed that there were no significant (P>0.05) differences in all the growth performance parameters except the total feed intake and average daily weight gain. There were no significant differences observed among the haematological parameters studied. The result of the feed cost analysis showed that feed cost/kg weight gain and total cost of production decreased as the levels of inclusion of bovine blood meal increased. The total revenue and net returns increased with the increasing levels of dietary inclusion of bovine blood meal. It was therefore observed that 15% inclusion level of bovine blood meal is adequate for finisher broiler chickens without adverse effect on their normal growth and development. It was also observed that it is relatively cheaper to feed broiler chickens with bovine blood meal based diets rather than the diet containing fish meal as protein source ingredient alone.
Abordagem atual da endometriose: implicações patogênicas e terapêuticas
Authors: Victor Santos Brito Paulo , Lavinas Lúcio da Silva Caroline , Genielly Camilo Bezerra Evelyn , Wolbeck Jungermann Priscila , Vytor Cardoso Nobre Paulo , Clemente Costa d’Oliveira Ruane , Andrade Brandão Camila , Vitória Sousa Gois Yasmin , Da Silva Santos Lorena , Carolina Dória de Melo Ana , Da Silva Peixoto Morgan , Antônio Gomes de Oliveira Marcos
Published: April 2024

Introdução: A endometriose é uma condição caracterizada pela presença ectópica de tecido endometrial funcional, ou seja, semelhante ao endométrio, fora da cavidade uterina. Esses implantes podem ser encontrados em várias regiões da pelve, como os ovários, ligamentos uterossacros, peritônio pélvico e outros órgãos adjacentes. Objetivo: Avaliar a patogênese e o manejo da endometriose. Metodologia: Trata-se de uma revisão bibliográfica que incluiu artigos originais e revisões sistemáticas em inglês e português, que abordaram os aspectos patogênicos e terapêuticos da endometriose, publicados entre 2012 e 2024, selecionados nas bases de dados PubMed, Scopus e SciELO. Após a seleção criteriosa, foram escolhidos 26 artigos para compor esta revisão bibliográfica. Resultados: O entendimento da patogênese da endometriose é essencial, a teoria mais reconhecida é a da menstruação retrógrada, outras teorias incluem a metaplasia celômica e os vestígios müllerianos. A interação inflamatória e angiogênica também é significativa. O manejo pode ser farmacológico ou cirúrgico, sendo que as opções farmacológicas variam desde antiinflamatórios, prostágenos até agonistas do GnRH. O tratamento cirúrgico, preferencialmente laparoscópico, é benéfico para casos de infertilidade, mas a preservação da função ovariana é crucial para mulheres que desejam engravidar. Considerações: A endometriose apresenta uma patogênese complexa com diversas teorias sobre sua origem, incluindo influências genéticas. O manejo envolve opções farmacológicas e cirúrgicas, com foco na redução dos níveis de estrogênio e no controle dos sintomas. Compreender esses mecanismos é crucial para desenvolver terapias mais eficazes e melhorar a qualidade de vida das pacientes.
ANÁLISE DO PERFIL EPIDEMIOLÓGICO DE PACIENTES INTERNADOS POR HIPERTENSÃO ARTERIAL SISTÊMICA PRIMÁRIA NO ESPÍRITO SANTO ENTRE 2019 A 2023
Authors: Lopes Ryan Nogueira , Rossetto Gabriel de Paula , Battisti Samuel de Souza , Cunha Karla Sant’Anna , Silva Franklim Barboza da , Nunes Daniel Santos , Oliveira Aline Bragança de , Santos Gabriel Ramalho , Leoni Davi Rosalino , Neto José Gonçalves da Silva , Luz Amanda Camello , Barreto Maria Vitória Ribeiro
Published: April 2024

A hipertensão arterial sistêmica primária é um dos principais problemas de saúde pública no mundo, afetando diretamente os gastos do sistema único de saúde brasileiro. Essa doença é multifatorial, tendo como base o estilo de vida, com hábitos que podem ser predisponentes, como: dieta inadequada, consumo de álcool, hipercolesterolemia, sobrepeso, sedentarismo e consumo abundante de sal. Assim, o diagnóstico precoce e manejo adequado é imprescindível, a fim de que se possa implementar hábitos de vida saudáveis como tratamento não-medicamentoso e, se necessário e dependendo do grau da HAS, tratar com medicamentos. Dessa forma, apesar de parecer simples, a aderência da maioria dos pacientes ao tratamento é difícil, o que ocasiona a piora do quadro de HAS e até mesmo problemas cardiovasculares, cerebrais e renais. Assim, o objetivo do presente estudo é descrever o perfil epidemiológico dos pacientes internados por hipertensão arterial sistêmica primária no Espírito Santo entre os anos de 2019 a 2023.
ASSISTÊNCIA DE ENFERMAGEM AO PACIENTE COM ACIDENTE VASCULAR ENCEFÁLICO: UM ESTUDO DE REVISÃO INTEGRATIVA
Authors: De Oliveira Santos Willians Henrique , Brito Monalisa Gois , Oliveira Ana Clara Farias de , Lima Sibelly dos Santos , Santos Soraya Meneses dos , Buss Ana Paula Teodoro , Lima Roseli Dias , Junior Jomar Reis Diniz , Freire Alyne Maria Lima , Sá Adriana Siqueira de , Sousa Elane Brito de , Rocha Letícia Ferreira , Silva Roseane dos Santos , Barros Regina Wanderley de , Oliveira Karolyne Rosa de
Published: April 2024

Esse estudo tem como objetivo descrever as condutas dos profissionais de enfermagem frente ao paciente vítima de AVE. O presente estudo trata-se de uma revisão de literatura do tipo integrativa, realizada nas bases de dados LILACS, Periódico CAPES e no SCIELO. Para a busca dos estudos foram utilizados os descritores: Acidente Vascular Cerebral “AND” Enfermagem, registrados nos Descritores em Ciências da Saúde. Os critérios de inclusão foram os estudos originais na íntegra disponíveis nas bases de dados indexadas, escritos em língua portuguesa, e que foram publicados entre o período de 2013 a 2023. Após a análise, leitura dos estudos e aplicação dos critérios de inclusão e exclusão, foram selecionados um quantitativo de 6 artigos para compor a revisão integrativa. Após a seleção dos estudos nas bases de dados, esses foram distribuídos em um quadro de dados contendo as seguintes informações: título, autor, ano, objetivo do estudo, local de realização, e abordagem do estudo. Diante do exposto percebe-se que a assistência dos enfermeiros de reabilitação torna-se imprescindível, pois está relacionada ao incentivo do autocuidado, auxilio no momento da higiene, a avaliação da marcha e do declínio cognitivo, corroborando para a evolução do quadro clínico dos pacientes. Os estudos também evidenciaram que o enfermeiro além de desempenhar a assistência, realiza atividades diagnósticas direcionadas a avaliação do suporte familiar e financeiro do paciente, assim como atividades de educação em saúde, que tornaram eficientes durante o enfrentamento da doença, possibilitando principalmente a prevenção de sinais depressivos.
Antecedents of Servitization Strategies in Manufacturing Firms and servitization's impact on firm performance: A theoretical and empirical analysis.
Authors:   , Abou-Foul Mohamad
Published: April 2024

Manufacturing firms have vigourously pursued opportunities for profitability and growth through service-led growth strategies. A major part of the existing literature has focused on such strategies and has shown that this phenomenon is prevalent and growing in most developed economies. However very little systematic evidence regarding the extent or consequences of servitization, based on comprehensive survey research yet exists. Furthermore the current body of research presents contradictory findings regarding the impact of servitization and firm performance. Drawing on the theoretical framework of the resource-based review, this research seeks to shed some light on this question through a survey of 185 US and European manufacturing firms along with the use of secondary financial data.
The Smart Way to Manage Family Finances For Beneficiary Families (KPM) Hope Family Program (PKH)
Authors: Ifi Misfi Laili
Published: April 2024

The problem of poverty is still a homework that has not been resolved by the government. Various efforts have been made, one of which is through the Family Hope Program (PKH), which is a conditional cash assistance for beneficiaries. It is said to be conditional because recipients must access education and health services using the grant funds received. However, based on information obtained from the companion, it is known that the recipients did not fully use the aid money according to its designation. This happens for various reasons, one of which is minimal income so they have to look for other sources to meet their daily needs. Therefore, this dedication is intended to provide an understanding of how to manage family finances so that whatever income is earned can be sufficient to meet life's needs, not a lifestyle. This dedication method is carried out with lectures, discussions and brainstorming with participants. The result of this service is that participants gain additional knowledge about budget planning, budget control, and distinguishing between needs and wants
A Synopsis of 3d Printing Technology : Materials, Applications and Technology
Authors: - Prathamesh D. Wankhade , - S. G. Jawarkar , - Dr. Monika P. Jadhao
Published: April 2024

Being an additive process, 3D printing has become a viable technique for the manufacture of technical components, in contrast to traditional manufacturing processes. 3D printing is a sustainable technology for industrial application because of its many benefits, including little material waste, simplicity of manufacture, low human participation, minimal post-processing, and energy efficiency. The merits and downsides of various 3D printing technologies are covered in the study. A thorough explanation of the many materials suitable for every kind of 3D printing method is provided. Each process type's numerous application areas are also presented in the study. There is also a special section on industry 4.0. The reviewed literature showed that while 3D printing has advanced to To a certain degree, there are still problems that need to be resolved, such material incompatibility and material expense. Subsequent investigations may be conducted to enhance and adjust the procedures to accommodate an extensive variety of substances. More attention has to be paid to
creating affordable printer technologies and materials that work with these printers in order to increase the number of applications for 3D printed items.
Evaluating the Long-haul Low-cost Airline Business Model: a Perspective on Disruptive Innovation
Authors: - Abdullah Ansari
Published: April 2024

This article explores how the long-distance low-cost airline business model is impacting the aviation industry through disruptive innovation. The LDLC business model is gaining traction and is set to challenge traditional network carriers in the mainstream market. As a result, significant strategic changes are on the horizon for long-haul air travel, requiring incumbents to adapt their approaches. We propose various strategic response options under avoidance, acceptance, and embracing of the LDLC business model that existing players can consider to maintain their competitive position in this evolving market. The paper provides valuable insight for airline managers seeking to reevaluate their organizations' strategies when confronted with a potentially disruptive innovation within their industry.
Aggression and Its Associated Factors among the Teenagers of Selected Schools in Kathmandu
Authors: - Neha Shrestha , - Kushum Kunwar , - Barsha Mahat
Published: April 2024

The study conducted among Kathmandu teenagers aimed to understand adolescent aggression and its associated risk factors. Using the Buss and Perry Aggression Questionnaire, data from 97 participants were analyzed using SPSS. While no significant associations were found, trends suggested higher aggression among males, class 9-10 students, Hindus, those in nuclear families, individuals with one sibling, moderate family incomes, regular social media users, and online gamers. This highlights the prevalence of moderate aggression among Kathmandu teenagers, emphasizing the need for further research and awareness campaigns on responsible social media and online gaming habits to address this issue.
Inclusive Education Practices: A Review of Challenges and Successes
Authors: - Sonali Bindhani , - Geetha Gopinath
Published: April 2024

Inclusive education, which aims to provide equal opportunities for all students regardless of their diverse backgrounds and abilities, has garnered increasing attention in recent years. This paper presents a comprehensive review of the challenges and successes encountered in implementing inclusive education practices. Drawing upon a wide range of literature, the review highlights the complexities involved in fostering inclusive environments within educational settings. The challenges of inclusive education are multifaceted and rooted in societal attitudes, inadequate resources, and systemic barriers. Attitudinal barriers include misconceptions and biases towards students with disabilities, which often result in segregation and discrimination. Furthermore, the lack of adequate funding and support services poses significant obstacles to implementing inclusive practices effectively. Systemic barriers, such as rigid curriculum frameworks and standardized testing, can also hinder the provision of individualized support and accommodations for diverse learners. Despite these challenges, numerous success stories and promising practices demonstrate the potential of inclusive education to positively impact students, educators, and communities. Successful inclusive education initiatives prioritize collaboration among stakeholders, including teachers, parents, and community members, to create supportive learning environments. Moreover, inclusive schools embrace a holistic approach that values diversity, promotes empathy and understanding, and fosters a sense of belonging among all students. Key factors contributing to the success of inclusive education include teacher training and professional development, flexible curriculum design, and access to specialized support services. Educators play a central role in creating inclusive classrooms by adopting inclusive pedagogies, differentiating instruction, and fostering positive relationships with students. Furthermore, leveraging assistive technologies and universal design principles can enhance accessibility and support the diverse needs of learners. Inclusive education not only benefits students with disabilities but also promotes social cohesion and diversity appreciation among all students. Research indicates that inclusive classrooms foster positive attitudes toward diversity, reduce stigma, and enhance academic achievement for all students. Furthermore, inclusive education prepares students for the complexities of the real world by promoting empathy, tolerance, and respect for differences. This review contributes to the growing body of literature on inclusive education by synthesizing current research findings, identifying key challenges, and highlighting successful strategies for fostering inclusive practices within educational settings.
Threat to Civil Aviation – Hijacking
Authors: - SALONI KUMARI GUPTA , - VIVEK PATTABIRAMAN
Published: April 2024

Abductions of hostages in India's civil aviation industry endanger the lives of Indian nationals and the entire country. In this paper, we take a close look at this threat from every angle: its background, present security measures, geopolitical factors, terrorist threats, internal security challenges, response and preparation efforts, technology, international cooperation, passenger awareness, and technology. Airline safety is becoming more of a priority than it was in the past due to the average attack severity skyrocketing, even if hijackings have generally decreased in frequency over the last several decades. In order to construct a taxonomy, this "incident-driven" study of a new database of hijackings that took place from 1993 to 2003 examined 27 traits of hijackings recorded in public sources. The four factions are associated with distinct terrorist acts. Number of perpetrators, severity of armed violence, affiliation with official groups, place of origin of flight, and international or domestic nature of the journey were some of the variables that grouped them into clusters. When comparing the four groups' strategies and chances of successfully resolving the attack, there was a significant difference.