bluuebunny/crossref_metadata_2025 huggingface dataset:
Changing the technical characteristics of conveyors with a suspended belt in case of failures in the power supply system of drive suspensions
Authors:   Bryansk State Technical University, Tolkachev E.N.
Published: September 2021

The results of the research presented in the article relate to a fundamentally new type of continuous transport machines-conveyors with a suspended load-carrying belt and a distributed drive. The main advantages of which are due to the features of the kinematic scheme, in which the load-bearing conveyor belt is held by the sides by means of roller suspensions on rolling guides closed along the route and does not interact with its base with supporting supports, and the drive is implemented according to the distributed scheme by the equipment of individual suspensions with individual motor-gear drives. A feature of such a kinematic scheme is the nature of the failures associated with the operation of highly loaded drive suspensions, the influence of which affects the main technical characteristics of the conveyor with a sufficiently increased number. The paper presents a mathematical model designed to calculate the dynamic characteristics of a conveyor with a suspended belt and a distributed drive when the types of failures characteristic of this conveyor design occur, associated with a break in the supply electrical circuit of the motor-gear drive of the suspensions. Based on the developed mathematical model for the reference design of a conveyor with a suspended belt and a distributed drive, a series of numerical calculations of dynamic characteristics in the event of failures of drive suspensions is performed. The obtained results allowed us to establish that with a reduction in the number of groups of consistently failed drive suspensions located with an equal step along the route, the technical characteristics of the conveyor deteriorate: the speed of movement of the load-bearing belt and the total power of the drives are reduced, and the longitudinal tensile stresses in the belt are increased. With an increase in the number of consistently failed drive suspensions within one group, the power and speed of the conveyor decrease non-linearly, and the longitudinal stresses in the conveyor belt increase linearly. In general, the results of calculations of the technical characteristics of the reference idealized design demonstrated the possibility of the conveyor operation in case of failure of 90% of the drive suspensions. The actual performance indicators are determined by the technical characteristics of the used gear motor drives.
Guarding Thought against Self-Destruction. Contradiction and Identity in Cohen and Hegel
Authors: Wiedebach Hartwig
Published: September 2021

Hermann Cohen's Logic of Pure Knowledge and G. W. F. Hegel's Science of Logic each use in their way the means of thought of negation and contradiction to unfold the philosophical dynamic: a fragile interplay between self-endangerment and self-preservation of thought. Here, the proximity and difference of the two authors are extended. The proximity lies in methodological negativism. The difference is in the significance of the principle of continuity. According to Cohen and Hegel as well, thinking proceeds exclusively, as Kant called it, synthetically. The exclusion of contradiction, limited to analytical judgments, has only marginal significance. But the commonality does not eliminate the differences. As Hegel puts it, contradiction is a principle of mediation and finally results in "self-dissolution"; it carries within itself a direction of logical "reconciliation." Per Cohen, contradiction is a principle of "annihilation" (annihilatio) of approaches to a determination that threatens any form of "identity." The turn Hegel put in contradiction itself, regarding in it a unity of positivity and negativity, has no direct counterpart in Cohen. Nevertheless, for him, too, the "judgment of contradiction" becomes the active basis of all cognitive thought. By exercising a contradiction-destroying "activity," the judgment of contradiction "protects," indeed "generates," the real possibility of cognition. The annihilation of the non-identical sets free the fundamental "judgment of origin" with which cognition finds its beginning. The principle of continuity taken over from Leibniz corresponds to it. Just this principle has now again no direct correspondence with Hegel.
Timelessness of C.G. Jung and Super-Temporality of N.O. Lossky: Comparative Analysis
Authors: Balanovskiy Valentin V.
Published: September 2021

The article compares views of C.G. Jung and N.O. Lossky on the nature of time, including in the context of contemporary to them physical theories - quantum mechanics by W. Pauli and relativistic physics by A. Einstein. In particular, the author points to the similarity of ideas of both thinkers that the psyche relativizes time not only subjectively, but also objectively. Jung and Lossky provide this statement with a similar empirical basis, for example, the researches of T. Flournoy, as well as similar theoretical arguments by postulating a fundamental acausal principle of the connection of all things, which is better suited for describing psychic and some physical phenomena than the classical causal explanation. In analytical psychology, such a principle is synchronicity, in hierarchical personalism - gnoseological coordination. Both concepts are genetically related to the G.W. Leibniz idea of pre-established harmony, which was reinterpreted by Jung and Lossky through different worldview foundations. Jung in his reasoning relied on the transcendental idealism of I. Kant, the principle of complementarity and the discoveries of quantum mechanics, Lossky - on intuitivism, the principle of subordination and on his own interpretation of Einsteins theories. Jung comes to the conclusion that the psyche has a timeless character, and Lossky comes to the conclusion that it has a super-temporal character. Jungs timelessness indicates the transcendental nature of psyche and the strive to get away from the classical causal explanation, saving it according to the principle of complementarity only to consider the phenomenal side of being and mainly physical processes. One of the pioneers of quantum mechanics Pauli was of the same opinion in general. Because of there is nothing transcendent in hierarchical personalism, Losskys super-temporality is of a strive to find a deeper basis for occurring in time processes, and, according to the principle of subordination, to include time in the hierarchical structure of the universe, prescribing for it a role of one of the two key forms of psychic and psycho-material processes characteristic of a certain stage of being.
Cores e pedagogias do discurso zapatista
Authors: Andrade Antonio , Araujo Fernandes Patricia
Published: September 2021

Neste artigo, dedicamo-nos a refletir sobre a inflexão pedagógica decolonial do discurso zapatista, trazendo à discussão o papel simultaneamente político e educacional que a apropriação de um texto narrativo literário indicia nesse contexto de militância. Para tanto, analisamos o comunicado do Exército Zapatista de Libertação Nacional (EZLN) – movimento de resistência indígena mexicano – intitulado La historia de los colores, escrito pelo Subcomandante Marcos. Para a elaboração do dispositivo teórico-analítico deste trabalho, articulamos, de maneira transdisciplinar, a perspectiva dos estudos discursivos (ORLANDI, 2001; FOUCAULT, 1988), as indagações advindas das ciências sociais a respeito das epistemologias do Sul (SANTOS, 2018) e o debate relacionado à pedagogia decolonial (WALSH, 2013; CANDAU, 2010).
Kara chłosty w społeczeństwie Singapuru Sądowy i szkolny wymiar kar cielesnych
Authors: Nowosad Inetta
Published: September 2021

Celem artykułu jest podjęcie dyskusji nad stosowaną w Singapurze karą chłosty z perspektywy osoby z „zewnątrz”. Zwrócono uwagę na zrozumienie zjawiska, w tym przeszłości kolonialnej, ale również zakorzenionych w kulturze wartości z uwzględnieniem przyszłych potrzeb kraju. W przyjętym podejściu wyłaniają się napięcia pokonywane przez silną orientację na przestrzeganie norm prawnych. Analizie poddano sądowy i szkolny wymiar kary chłosty jako kary zasadniczej, by na ich przykładzie rozpoznać społeczne znaczenie kar cielesnych i ich siłę. W tym przypadku również akceptację dla kar cielesnych w rodzinie jako elementu dyscypliny i oddziaływań wychowawczych. Argumenty i dowody przedstawione w artykule opierają się głównie na przeglądzie literatury przedmiotu, rezultatów badań prowadzonych w tym obszarze, analizie dokumentów źródłowych oraz nagłaśnianych medialnie artykułów prasowych i wypowiedzi na portalach społecznościowych.
Polska adaptacja kwestionariusza SSICR do pomiaru poczucia stygmatyzacji osadzonych
Authors: Friedrich Wiola
Published: September 2021

Niniejsze badania prezentują polską wersję kwestionariusza Poczucia Stygmatyzacji (Self-stigma of Individuals with Criminal Records – SSICR) do pomiaru poczucia stygmatyzacji osadzonych. Procedura adaptacyjna została przeprowadzona zgodnie ze standardami sprawdzania równoważności testów na grupie 186 osób w wieku od 19 do 84 lat (M = 36,4; SD = 11,7). Rzetelność oszacowano na podstawie wskaźników α Cronbacha, trafność czynnikowa została zweryfikowana na podstawie konfirmacyjnej analizy czynnikowej. Zbadano również trafność narzędzia. Otrzymane wyniki pozwalają twierdzić, że SSICR jest narzędziem o akceptowalnych właściwościach psychometrycznych.
Nadzór sądowy nad procesem resocjalizacji więźniów w polskim systemie penitencjarnym
Authors: Łapiński Piotr
Published: September 2021

W polskim systemie penitencjarnym nadzór nad legalnością i prawidłowością wykonywania kar izolacyjnych oraz tymczasowego aresztowania sprawują sędziowie penitencjarni. Analiza regulacji określających zakres tego nadzoru prowadzi do wniosku, iż jego sprawowanie wymaga przede wszystkim biegłości w interpretowaniu i stosowaniu prawa, np. dla oceny zgodności z prawem postępowania administracji więzień czy przy wyjaśnianiu prawidłowych zastosowań konkretnych przepisów. Jednak pełny zakres nadzoru penitencjarnego współtworzą zadania, które stawiają sędziów penitencjarnych przed koniecznością dysponowania kompetencjami umożliwiającymi ocenę prawidłowości realizowanych oddziaływań zmianotwórczych wobec osób osadzonych. Powstaje za tem pytanie o zasadność oraz możliwości realizacji nadzoru penitencjarnego przez sędziów penitencjarnych w tak szerokim zakresie. W poszukiwaniu odpowiedzi pozyskano opinie wychowawców penitencjarnych dotyczące faktycznych obszarów nadzoru sprawowanego przez sędziów penitencjarnych, sposobów jego sprawowania oraz oczekiwań wychowawców dotyczących nadzoru penitencjarnego, z uwzględnieniem realizowanego przez nich procesu resocjalizacji.
Efektywność oddziaływań korekcyjno-edukacyjnych w zakładach karnych wobec sprawców przemocy w rodzinie w świetle powrotności do zakładu karnego
Authors: Więcek-Durańska Anna
Published: September 2021

Przemoc w rodzinie jest zjawiskiem, na temat którego od wielu lat toczą się burzliwe dyskusje zarówno w mediach, polityce, jak i w środowisku naukowym. Podkreśla się, że we współczesnym świecie jest to zjawisko coraz bardziej widoczne i narastające. Wedle oficjalnych statystyk rokrocznie za znęcanie się nad członkiem rodziny (art. 207 k.k.) skazuje się około 10 tys. osób, z czego część sprawców odbywa karę bezwzględnego pozbawienia wolności – nierzadko w warunkach recydywy penitencjarnej. Sprawcy w warunkach izolacji penitencjarnej poddawani są różnym oddziaływaniom korekcyjnym. W niniejszym artykule przedstawiono wyniki badań dotyczące efektywności oddziaływań programu korekcyjno-edukacyjnego Duluth, adresowanego do sprawców przemocy w rodzinie. Wyniki przeprowadzonych analiz przedstawiono w perspektywie powrotności do zakładu karnego po upływie pięciu lat od jego opuszczenia.
Encore
Authors: Mika Elo
Published: September 2021

The exposition presents two installations—Mitä uutta kivistä?/Anything new about stones? (2017) and LAB-O(U)RATORY (2019)—and enfolds them in a series of repetitive gestures that stage their methodical entanglement. Both of the installations explore and articulate the research potential of expanded writing. At stake is the ecology of attention in a setting that thematises the co-existence of different modes of articulation, interlinked spatial and temporal arrangements as well as their associative mechanisms. What happens when a spatial constellation is presented on a medially formatted time line? How to focus one’s attention in an associatively saturated literary space? Rather than attaching itself to an already existing theoretical framework or meta-discussions on artistic research, the exposition aims at explicating a singular artistic framework and its constellated structure.
Beyond the Visual - A research curriculum for explorations in spatiotemporal environments
Authors: Constantinos Miltiadis  , Gerriet K. Sharma
Published: September 2021

Virtual reality and spatial audio technologies bring about a new paradigm in the fields of architecture and music. Works developed in these media produce experiences beyond what is perceivable in the physical world, extending therefore our capacities to design/compose as well as our sensibilities for spatial and temporal perception. By operating in the spatiotemporal domain, these new media, question our disciplinary understandings of space and time as well as their aesthetics, requiring an altogether new post-disciplinary conception of design/composition and experience.
"Beyond the Visual" is a research curriculum for the investigation of spatiotemporal aesthetics, in the interface between architecture and music, in regard to perception and creativity and design/composition.

This exposition is part of the research agenda of the Society of Artistic Research Special Interest Group (SIG): Spatial Aesthetics and Artificial Environments.
Raising the Voice: Sculptural and Spoken Narratives from the Flat Sheet
Authors: Hannah Clarkson
Published: September 2021

This exposition explores ideas of narrative and storytelling through sculptures and texts raised from a flat sheet, a kind of visual and spoken poetry which is both particular and multiple.

In this paper, the key area of investigation will be the relationship between sculptural and spoken narratives in my practice. This is engaged with in four main areas:
• The flat sheet and the fold as sites for storytelling
• Multiplicities inherent to storytelling
• Architecturality and the space between bodies and buildings
• Words, text and the voice, and their relationship to sculpture

I explore the role of the architectural in the space between sculptural and spoken narratives, both of which are forms that begin with a flat sheet. The research also looks at how one might write about art in order to expand understanding but not reduce it to one meaning, writing around or through objects so as to leave gaps for the imagination and other narratives. The importance of the voice in the telling of these narratives is investigated, as well as the relationship between bodies and buildings.
Glass Cities
Authors: Zoe Panagiota (aka Betty) Nigianni
Published: September 2021

Single-channel digital video designed as a video installation for the live music performance by Elica. Shown at: Small Music Theatre, Athens, Greece, 2007.
You and Me and Everything Around Us
Authors: Zoe Panagiota (aka Betty) Nigianni
Published: September 2021

Single-channel video with text and voice-over. Invitation at the Women Artists' Movement Show, The Crypt Gallery, London, 2009.
Angela Ramette
Authors: Angela Ramette
Published: September 2021

Die künstlerische Forschungsarbeit ‚Eine Anatomie der Macht‘, erforscht ein klassisches sozialarbeiterisches Paradigma, das ‚Machtgefälle‘ zwischen, Klient_in und Sozialarbeiter_in, sowie die implizite Machtstruktur sozialarbeiterischer Interventionen, als exemplarische Fragestellung und Anwendungsbeispiel, durch künstlerisch- ästhetische Mittel. Über die künstlerische Forschungsarbeit wird das Thema visualisiert und körperlich- sinnlich erfahr- und erforschbar. Die zu Grunde liegende Forschungsfrage lautet: Wie beforsche ich ein Thema oder eine Fragestellung der Sozialen Arbeit über ästhetisch-künstlerische Mittel, und welche Methode lässt sich aus den Ergebnissen des exemplarischen Forschungsvorgangs ableiten?

Entstanden im Rahmen eines Reflexionsseminars zur professionellen Rolle des/der Sozialarbeiter_in, des Bachelorstudienganges Soziale Arbeit, beinhaltet das originäre Forschungsprojekt der Künstlerin, Ansätze, welche auch im Kontext Lehre und dem ‚forschenden Lernen‘, partizipative Zugangsmöglichkeiten ermöglichen. In dieser Verbindung liegt die Kernhypothese der Künstlerin: künstlerische Forschungsdesigns für sozialarbeiterische Fragestellungen nutzbar und partizipativ anwendbar zu machen.
Die in der Performance verwendeten Materialien und Objekte können als ‚Sprachzeichen‘, ähnlich wie eine ‚Übersetzung‘ in die sinnlich- erfahrbare Welt, verstanden und analysiert werden. Über die künstlerischen Handlungen im Forschungsprozess, welche sich methodisch als ‚‘Denken/Reflektieren in der Kunst‘, ‚Improvisieren und Sammeln‘, und ‚Inszenieren‘ beschreiben lassen, führen eine Analyse und Reflexion zu einer Logik und Eindeutigkeit innerhalb der performativen Erzählung. Die daraus abgeleitete Methode, beschreibt eine ‚Probenforschung des Sozialen‘ und wird im folgenden Forschungsbericht detailliert vorgestellt. Die ‚Storyline‘ der inszenierten performativen Elemente, bietet während des Datenerhebungsprozesses, die Möglichkeit kollektivistisches Wissen, sichtbar und befragbar zu machen, und im angeschlossenen Publikumsgespräch in eine diskursive Form zu überführen.
Gut Feeling
Authors: Robertas Narkus
Published: September 2021

The research on the project
Queers, Crips, and Mermaids: Disruptive Bodies as Performative Objects
Authors: Kamran Behrouz
Published: September 2021

This chapter attempts to analyze and unfold interlinked layers of a research-performance, in two interconnected site-specific Acts. First Act (Collision) happened in St. Moritz 2020 and the second Act was performed a year later in Bern 2021 . By adopting the notion of “cosmopolitics” as a method, this Performance attempts to speculate inter-relativity of human and non-human bodies within the capitalist matrix of species hierarchy. Through comparative analysis of different psycho-cultural/political narratives, this text attempts to map out interconnected traumas of transspecies; wounds and scars that are older than our bodies, older than ourselves. This text uses diffractive reading of these two Acts through the histories of the figure of the mermaid and the witch, In order to queer the hegemonic interpretations of both figures.
Cloud Fidget
Authors: Sebastian Martinsen
Published: September 2021

A squishy fidget thing to light up your mood
Design of an educational strategy for environmental school programs in Colombia
Authors: Valderrama Lopez Christian Felipe , Fierro Olga , Ortiz Aviles Juan , Usa Peña Maria
Published: September 2021

There is a problem associated with the impact generated by environmental education in Latin American educational institutions and how it is reflected in the behaviour of students and its contribution to society. This research proposes the design of a sustainable strategy to develop Environmental Programs in Educational Institutions. The research was carried out in the city of Neiva – Colombia. A sample of 34 institutions was used, and an interview was conducted with three schools that reported successful environmental projects at a national level. It was found that by 2018 only 9% of educational institutions had successfully developed School Environmental Programs, 93% state that the availability of time is one of the biggest obstacles for its implementation, and 67% of these ensure that they have not received technical advice nor have the necessary financial resources.
Bibliometric Analysis of the Evolutionary Process of the Internet of Things
Authors: Ospina Ramos Javier Alberto , Hernández Abaunza Sergio , Leguizamón Páez Miguel Ángel
Published: September 2021

The current article presents a bibliometric anaylisis about the contribution made by the Internet of Things (IoT), from its appearance, viewed since social, academic and techonological levels. This analysis was carried out collecting information to a global standard, also it was reviewed more than 60.000 files, which are in the bibliogaphic database Scopus, by means of the techonological tool RStudio. This resource supports the processing of obtained data and whose main idea is to highlight the importance of different scientific and academic cooperations that are developed to national and international standard, which are focused on to research about this topic. It was used the method of information analysis, which consists in study design, data summary, proecessing and display, also the obtained results interpretation since the reckonings made through Rstudio. These results show that the IoT is a very important reference frame to its applicability in many production and services fields to a global level. It is also evident that the United States and China are nations that develop scientific production to a large-scale about the IoT, allocating a big quantity of human, physic and techological resources to such aim.
Venoarterio-Venous (VA-V) ECMO Configuration: A Single-Center Experience
Authors: Kukielski Casey , Davis Carlton , Saberi Asif , Chaudhary Sanjay
Published: September 2021

Patients in respiratory failure on VV ECMO may develop cardiovascular
dysfunction necessitating additional hemodynamic support, while patients
in cardiovascular failure on VA ECMO may require additional respiratory
support for concurrent gas exchange abnormalities. A hybrid
venoarterio-venous (VA-V) configuration provides both cardiac support
via a traditional arterial reinfusion cannula and respiratory support
via an additional venous reinfusion limb. We describe our single center
experience using VA-V ECMO for patients (n = 14, median age 54) with
combined cardiopulmonary failure or differential hypoxemia. Patients
were treated with ECMO support for a median of 148.2 (IQR 122.6 –
174.4) hours, consisting of 0 (IQR 0 – 1.8) hours of VA and 92.4 (IQR
58 – 115) hours of VA-V followed by 46 (IQR 0 – 95.5) hours of VV
support. Of these 14 patients, 11 survived to decannulation (79%) and 9
survived to hospital discharge (64%).
Deep vein thrombosis and pulmonary embolism in pediatric COVID-19
Authors: Ioannidou Loukia , Dettoraki Athina , Noni Maria , Koukou Dimitra , Michalopoulou Aiketarini , Kapsimalli Zoey , Botsa Evanthia , Michos Athanasios , Spoulou Vana , Pergantou Helen , Kanaka-Gantenbein Christina
Published: September 2021

Thrombotic complications of SARS-CoV-2 have been increasingly recognized
as an important component of COVID-19 in adults; however, they have been
less evident in children. We report a case of a teenager with positive
SARS‐CoV‐2 RT–PCR and underlying prothrombotic risk factors, including
aromatase inhibitor therapy, who developed deep vein thrombosis
resulting in pulmonary embolism. Laboratory tests revealed deranged
coagulation parameters (high D-dimers and Factor VIII and low
antithrombin). The patient required intensive care and was managed with
anticoagulants, dexamethasone and antithrombin concentrate. Clinical
condition and hemostatic profile gradually improved. A review of the
available literature for similar cases is presented.
REACTIVATION OF HERPES ZOSTER AFTER VACCINATION WITH AN INACTIVATED VACCINE: A CASE REPORT FROM NEPAL
Authors: SHAH SANGAM , Baral Bikash , Chamlagain Rajan , Murarka Hritik , Adhikari Yagya , Paudel Basanta Sharma
Published: September 2021

COVID-19 has been linked to a number of cutaneous symptoms in COVID-19
patients. Although herpes zoster (HZ) was the first sign of COVID-19
infection in several patients, cases of HZ after COVID-19 vaccination
are rare. We report case of 51 years old male with Herpes Zoster after
Sinopharm (Vero Cell).
Sequence and Regulatory Variation in Acetylcholinesterase Genes Contribute to Insecticide Resistance in Different populations of Leptinotarsa decemlineata
Authors: Margus Aigi , Piiroinen Saija , Lehmann Philipp , Grapputo Alessandro , Gilbert Leona , Chen Yolanda , Lindström Leena
Published: September 2021

Although insect herbivores are known to evolve resistance to
insecticides through multiple genetic mechanisms, resistance in
individual species has been assumed to follow the same mechanism. While
both mutations in the target site insensitivity and increased
amplification are known to contribute to insecticide resistance, little
is known about the degree to which geographic populations of the same
species differ at the target site in a response to insecticides. We
tested structural (e.g. mutation profiles) and regulatory (e.g. the gene
expression of Ldace1 and Ldace2, AChE activity)
differences between two populations (Vermont, USA and Belchow, Poland)
of the Colorado potato beetle, Leptinotarsa decemlineata in their
resistance to two commonly used groups of insecticides,
organophosphates, and carbamates. We established that Vermont beetles
were more resistant to azinphos-methyl and carbaryl insecticides
compared to Belchow beetles, despite a similar frequency of
resistance-associated alleles (i.e. S291G) in the Ldace2 gene. However,
the Vermont population had two additional amino acid replacements
(G192S, F402Y) in the Ldace1 gene, which were absent in the
Belchow population. Moreover, the Vermont population showed higher
expression of Ldace1 and was less sensitive to AChE inhibition by
azinphos methyl oxon than the Belchow population. Therefore, the two
populations have evolved different genetic mechanisms to adapt to
organophosphate and carbamate insecticides.
Altered Blood-Brain Barrier and Blood-Spinal Cord Barrier Dynamics in Amyotrophic Lateral Sclerosis: Impact on Medication Efficacy and Safety
Authors: Pan Yijun , Nicolazzo Joseph
Published: September 2021

The access of drugs into the central nervous system (CNS) is regulated
by the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB). A
large body of evidence supports perturbation of these barriers in
neurodegenerative diseases, including Alzheimer’s disease and
Parkinson’s disease. Modifications to the BBB and BSCB are also reported
in amyotrophic lateral sclerosis (ALS), albeit these modifications have
received less attention relative to those in other neurodegenerative
diseases. Such alterations to the BBB and BSCB have the potential to
impact on CNS exposure of drugs in ALS, modulating the effectiveness of
drugs intended to reach the brain and the toxicity of drugs that are not
intended to reach the brain. Given the clinical importance of these
phenomena, this review will summarise reported modifications to the BBB
and BSCB in ALS, discuss their impact on CNS drug exposure and suggest
further research directions so as to optimise medicine use in people
with ALS.
A Juvenile Pleomorphic adenoma of the palate
Authors: Hammami Bouthaina , Chaabouni Mohamed Amine , Yousfi Ghada , Walha Omar , Mnejja Malek , Achour Imen , Charfeddine Ilhem
Published: September 2021

Salivary gland tumors in children are rare, involvement of accessory
salivary glands is exceptional. We report a case of pleomorphic adenoma
of the palate in a child in order to describe the clinical, radiological
features, as well as the management of this rare localization.
GPR55 antagonist CID16020046 protects against atherosclerosis development in mice by inhibiting monocyte adhesion and Mac-1 expression
Authors: Lee Seung-Jin , IM DONG-SOON
Published: September 2021

Background and Purpose: GPR55 is a G protein-coupled receptor that
recognizes several lipid molecules. GPR55 expression in human monocytes
and its proinflammatory role lead us to investigate the role of GPR55 in
monocyte adhesion and atherosclerosis development. Experimental
Approach: We investigated monocyte adhesion in human THP-1 monocytes and
atherosclerosis development in ApoE-/- mice by using O-1602 (a potent
agonist of GPR55), CID16020046 (a specific GPR55 antagonist), and a
high-fat diet-induced atherosclerosis model. Key Results: In human THP-1
monocytes, treatment with O-1602 signiﬁcantly increased monocyte
adhesion to human umbilical vein endothelial cells (HUVECs), and the
O-1602-induced adhesion was inhibited by treatment with CID16020046.
O-1602 induced the expression of Mac-1 adhesion molecules, whereas
CID16020046 inhibited this induction. Analysis of the promoter region of
Mac-1 elucidated the binding sites of AP-1 and NF-κB between nucleotides
-750 and -503 as GPR55 responsive elements. Furthermore, O-1602
induction of Mac-1 through AP-1 and NF-B was found to be dependent on
the signaling components of GPR55, that is, Gq protein, Ca2+, CaMKK, and
PI3K. In an in vivo study of high-fat diet-induced atherosclerosis in
ApoE-/- mice, administration of CID16020046 ameliorated atherosclerosis
development. These results suggest that high-fat diet-induced GPR55
activation leads to adhesion of monocytes to endothelial cells via
induction of Mac-1, and CID16020046 blockage of GPR55 could suppress
monocyte adhesion to vascular endothelial cells through suppression of
Mac-1 expression, leading to protection against the development of
atherosclerosis. Conclusions: This report suggests that GPR55 may be a
therapeutic target for atherosclerosis development.
Patient-tailored effective dosing for fluoroquinolones: role of interindividual pharmacokinetic and pharmacodynamic variability
Authors: Estrade Oskar J , Vozmediano Valvanera , Carral Nerea , Gonzalez Margarita , Poole Rachel , Suarez Elena
Published: September 2021

Fluoroquinolone’s (FQs) pharmacological properties, patient
characteristics, and microorganisms responsible for infection play a key
role in clinical outcomes. FQs are prescribed in systemic infections due
to the adequate disposition properties of the antibiotic at the site of
infection. However, variability in important interindividual
pharmacokinetic aspects, especially in the elimination process, may
contribute to treatment failure. Likewise, today, undesired
interregional variability in FQs antimicrobial activity against certain
microorganisms exists. The aim of this study was to review the published
information about interindividual variability in pharmacological
processes for the most used FQs, such as ciprofloxacin, levofloxacin,
and moxifloxacin. This review was deemed necessary on the basis of
understudied interindividual pharmacokinetic and pharmacodynamic
variability of FQs. The understanding of FQs dose-response relationship
is critical to optimize the effectiveness of FQs therapy used to treat
systemic infections. This may be particularly critical in the case of
special populations such as critical ill, elderly, renal, and obese
patients. The altered PK in these patients associated with creatinine
clearance, together with the variability in pathogen susceptibility,
associated with local resistances, may require personalized dosing
regimens. Patient-tailored effective FQs dosing is needed to guarantee
antimicrobial efficacy while minimizing the risk of adverse events and
emergence of resistance.
DIAGNOSING GRANULOMATOUS DISEASE DURING APPENDECTOMY
Authors: Senayli Atilla
Published: September 2021

Difficulties during surgery are uncommon situations in appendectomy. For
granulomatous appendicitis, literature is insufficient about surgical
findings. The procedure of a 17-year-old male patient was a struggle due
to adhesions. I thought a surgeon could expect granulomatous diseases by
evaluating the macroscopic appearance of the appendix during surgical
procedure.
Is Exogenous Fatty Acid Hydroperoxide Perception as Elicitor Related to Modulation of Plant Plasma Membrane Structure ?
Authors: Deboever Estelle , Aubel Géraldine van , Rondelli Valeria , Koutsioumpas Alexandros , Mathelie-Guinlet Marion , Dufrêne Yves , Ongena Marc , Lins Laurence , Cutsem Pierre Van , Fauconnier Marie-Laure , Deleu Magali
Published: September 2021

Oxylipins are lipid-derived molecules that are ubiquitous in eukaryotes
and whose functions in plant physiology have been widely reported. They
appear to play a major role in plant immunity by orchestrating reactive
oxygen species (ROS) and hormone-dependent signalling pathways. The
present work focuses on the specific case of fatty acid hydroperoxides
(HPOs). Although some studies report their potential use as exogenous
biocontrol agents for plant protection, evaluation of their efficiency
in planta is lacking and no information is available about their
mechanism of action. In this work, the potential of
13(S)-hydroperoxyoctadeca-(9Z,11E)-dienoic acid (13-HPOD) and
13(S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoic acid (13-HPOT), as plant
defence elicitors and the underlying mechanism of action are
investigated. Arabidopsis thaliana leaf resistance to Botrytis cinerea
was observed after root application with HPOs. They also activate early
immunity-related defence responses, like ROS. As previous studies have
demonstrated their ability to interact with plant plasma membranes
(PPM), we have further investigated the effects of HPOs on biomimetic
PPM structure using complementary biophysics tools. Results show that
HPO insertion into PPM impacts its global structure without solubilizing
it. Relationship between biological assays and biophysical analysis
suggests that lipid amphiphilic elicitors that directly act on membrane
lipids might trigger early plant defence events
Investigation the effect of newly used polymer modified bitumen on the performance of hot mix asphalt containing reclaimed asphalt pavement
Authors: Chafat Osamah H. , Al-Ghurab Sahar B. , Al-Humeidawi Basim H.
Published: September 2021

The current research focuses on investigating the effect of using reclaimed asphalt pavement (RAP) on performance of hot mix asphalt (HMA) prepared with polymer modified bitumen (PMB) binder. This PMB used for the first time with HMA contained RAP. The mechanical properties and performance of HMA were assessed using several standard tests including Marshall, indirect tensile strength, creep compliance, and wheel track test. The RAP replacement was conducted up to 70% of total aggregate in HMA with an increment of 10%. The results of investigation showed, that the use of PMB binder prepared by addition novolac (phenol formaldehyde solid resin) and hexamine to conventional bitumen, significantly improved the performance of HMA contained RAP. Also, the optimum percentage of RAP replacement was found to be 50% of total aggregate in HMA. For this level of replacement, the rut depth reduced up to 38% of its original value.
Enumeration of Hamiltonian cycles on a thick grid cylinder - Part II: Contractible Hamiltonian cycles
Authors: Bodroza-Pantic Olga , Kwong Harris , Djokic Jelena , Doroslovacki Rade , Pantic Milan
Published: September 2021

Here, in Part II, we proceeded further with the enumeration of Hamiltonian
cycles (HC's) on the grid cylinder graphs of the form Pm+1?Cn, where n is
allowed to grow and m is fixed. We proposed two novel characterisations of
the contractible HC's. Finally, we made a conjecture concerning the
dependency of the asymptotically dominant type of HC's on the parity of m.
Knowledge, attitude, and behaviors of pregnant women about COVID-19: a single-center cross-sectional study
Authors: Turan Gökçe
Published: September 2021

Objective Our aim is to assess the knowledge, attitude, and behaviors of pregnant women about COVID-19. Methods This cross-sectional survey study was performed on pregnant women in their second and third trimesters between November–December 2020. The participants completed a questionnaire consisting of 5 parts. Demographic data of pregnant women, their knowledge, attitude, and risk perceptions toward COVID-19, their practices and worries about COVID-19, and what they knew about pregnancy were calculated as percentile and mean values. Results A total of 1011 participants were included in the statistical analysis. The mean age and BMI of the participants were 27.09±5.55 and 27.48±4.71 kg/m2, respectively. Mean gestational age and parity were 26.20±9.30 and 1.47±1.19, respectively. Measures taken by authorities for COVID-19 were thought to be “extremely adequate” by 21.4% of the participants and “highly adequate” by 30%. Of the participants, 47.5% trusted healthcare professionals extremely in fighting against the COVID-19 pandemic. Affection and respect for healthcare professionals during the pandemic increased in 89.1% of the participants. Of the participants, 88.5% stated that they would follow the strict quarantine requirements when necessary and 48.3% felt more vulnerable/weak as they were pregnant during the pandemic. Of the participants, 50.6% were intending to decrease their antenatal visits during the COVID-19 pandemic. Conclusion The measures taken can be applied with high awareness of COVID-19. Sufficient training, in that case, can be done through communication routes such as information and public service announcements.
2019冠狀病毒病疫情下的疫苗猶疑與強制疫苗接種：初步的道德評估
Authors: CHAN Benedict S. B. , CHEUNG Chi Ngai
Published: September 2021

LANGUAGE NOTE | Document text in Chinese; abstract also in English.

疫苗猶豫，亦即延遲甚至拒絕接受疫苗接種，不只是人們對科學有多少了解的問題，亦混雜着不同信念和對權威的不信任。另一方面，有支持強制接種疫苗人士認為，因為疫苗是相對安全的方法令得社會達至群體免疫；權衡輕重之下，強制接種是道德上可以容許的做法。社會能否要求民眾強制接種新冠疫苗，抑或是疫苗猶豫有其合理性，應予尊重，是一個值得我們探討的道德課題。

本文會用以下的方式探究此項課題。歷來有不少學者提出各類支持強制接種麻疹疫苗的理由。另一方面，我們亦必須考慮各類支持疫苗猶疑的理由。正反的道德論證，皆涉及不能約化，但是在不同情境需要比較和排序的價值。我們會論證應以阿馬蒂亞•森(Amartya Sen)提出的後果評價作為道德推論和基礎去評估這些多元價值。在後果評價的基礎上，才可以比較接種新冠疫苗與麻疹疫苗在道德上的異同，並由此建立一套框架去評估強制疫苗接種的道德議題。

Vaccine hesitancy, a delay in acceptance or even refusal of vaccination, is a problem not only linked to public knowledge of science but also caused by complex beliefs and a lack of confidence in authority. People who support coercive vaccination argue that vaccination is a comparatively safe path for people in a community to reach herd immunity. Weighing the benefits and costs, coercive vaccination is morally permissible. However, whether we should enact it for Covid-19 vaccines or respect people who have vaccine hesitancy is a moral issue worthy of detailed investigation. Similar debates have also been around coercive use of the measles vaccine, which will serve as a point of comparison in this evaluation.

There are different kinds of arguments for and against policies of coercive vaccination, but whether positive or negative, they involve values that are incommensurable but should be compared and ranked accordingly in different situations. We argue that consequential evaluation, as suggested by Amartya Sen, forms the moral reasoning and foundation to evaluate these plural values. Using consequential evaluation, we can compare the moral similarities and differences between Covid-19 vaccines and measles vaccines and develop a framework to evaluate the moral issue of coercive vaccination.
試析西方倫理學中的孝養義務
Authors: XU Hanhui
Published: September 2021

LANGUAGE NOTE | Document text in Chinese; abstract also in English.

在西方倫理學中，孝養義務是指（成年）子女對父母尤其是對年邁父母所具有的提供保障、照料、陪伴及滿足其他合理需求的道德責任。與之相關的理論有感恩理論、友誼理論和特殊善理論。對於親子關係的模式、孝養義務的來源、孝養義務的具體要求、以及孝養義務何時能夠結束等問題，三種理論給出了各不相同的回答。本文嘗試探討這三種理論，並對其各自存在的問題給出批評和可能的回應。

In the Western tradition, filial obligation dictates that adult children have a moral duty to provide financial and psychological support to their aging parents. In addition, children are required to meet their parents' “reasonable demands” under given circumstances. There are three accounts of filial obligations that provide specific answers to questions concerning parent-child relationships, such as on what grounds and when filial obligation is encouraged and required. In this paper, the author explores the idea of filial obligation in the West and offers a critical response to the issues involved.
The phenomenon of modern Crimean citizen journalism: survey results
Authors: Iuksel Gaiana Z. , Sydorenko Natalііa M. , Dosenko Anzhelika K. , Sytnyk Oleksii V. , Dubetska Oksana O.
Published: September 2021

The purpose of the study is to cover the characteristic, the development of common Crimean citizen journalistic movement features as a social phenomenon, a phenomenon that arose after the occupation through the identification of a modern journalist portrait. The study uses the general scientific method of empirical research as the main one, the sociological method of a questionnaire survey, as well as the methods of classification, generalization, observation, statistical calculation. An analysis of a survey of Crimean citizen journalists demonstrates the existence of an active, mobile community in Crimea that seeks to provide information and human rights nonviolent resistance to the occupation.
ESTIMATING EFFICIENCY OF POND ELECTRIC SEINE NETS OPERATION
Authors: Kostrykin Dmitriy Alekseevich , Grozesku Yulia Nikolaevna
Published: September 2021

The article considers the problem of low productivity of many fish farms, especially non-drainage ponds against the background of a growing increase in the volume of fish farming, which is typical for pond fish farming in Russia. It has been found that one of the main factors of low productivity (1–5 c/ha) is the imperfection of existing tools and methods of fishing. With significant costs of manual labor and time, the catch of farmed fish is no more than 50%. The remaining fish die mostly during winter fish kills. To reduce the proportion of manual labor and improve the efficiency of fishing in non-drainage ponds, many countries are looking for the methods to modernize existing or develop new fishing gear. The most promising in this respect are electric breeders for fishing in the non-drainage ponds, small lakes and water reservoirs. The advantages of this method are the coverage of a large fishing zone, the possibility of catching fish leaving ordi-nary seines, and work in silted and tied water bodies. Studying the regularities of the electric field impact on fish is necessary to explain and predict its behavior in electric fields, to develop technical means that provide the necessary control activity, to develop measures to protect ichthyofauna from the harmful effects of electric fields, etc.
REACTIONS OF KIDNEYS OF SILVER BREAM (BLICCA BJOERKNA) FROM VOLGA DELTA TO HABITAT
Authors: Burlakov Ivan Alexeyevich , Kryuchkov Victor Nickolaevich , Volkova Irina Vladimirovna
Published: September 2021

The article focuses on the intensive anthropogenic impact on the aquatic ecosystems, which makes it necessary to monitor the populations of different fish species. The method of mor-phophysiological indicators was used to study the kidneys of silver bream in different water bodies of the Volga Delta. The morphometric characteristics of the kidneys of silver bream are presented. It is shown that the reactions of organs and body systems are caused by the environmental impact on the living organisms, which results, in particular, in the pathological changes in the fish body. Reactions in the body of fish are the result of a combined effect of environmental factors and natural physiological processes related to feeding, migrations, generative cycles, etc. The detected changes in the organ structure make it possible to assess the impact of the environment on fish. The seasonal and sexual variability of the indices of the mesonephros of silver bream from the Volga Delta is shown. Analysis of the kidneys of fish from two water bodies showed the variability of kidney mass due to the anthropogenic load on the water body, in particular, an increase in the kidney index in silver bream Blicca bjoerkna was registered in the ecosystem with an increased toxic load. It has been stated that the increase in the relative mass of mesonephros was caused by the changes in the organ. Changes were detected both in the intratubular tissue, and in the convoluted tubules and renal capsules. The study helped to find the differences in the relative weight and structure of the kidneys of silver bream, which lives in the water bodies with different anthropogenic load. A real increase of the kidney index was found in fish from the water body with a higher level of anthropogenic impact.
ASSESSMENT OF TROUT NATURALIZATION IN WATER BODIES IN NORTH-EASTERN EUROPEAN RUSSIA (CASE OF VYCHEGDA RIVER TRIBUTARIES)
Authors: Zakharov Alexander Borisovich , Boznak Eduard Ivanovich
Published: September 2021

The article highlights the ichthyological studies carried out in the Sysola river basin (a second order tributary of the Severnaya Dvina river), where rainbow trout is reared in cages for commercial purposes in the waters of regulated tributaries. The forecast for trout naturalization seems to be poor due to the fact that trout of different ages enter the river system every year as a result of technological accidents. It has been found that, despite the numerous cases of trout occurring in the natural conditions during 40 years, in the basin of the Sysola river has not formed a self-reproducing population of rainbow trout, and cases of its by-catch are rare. The data on the climatic and ecological conditions of the region are given. It has been inferred that the main factors preventing the naturalization of trout in the water bodies of the region are unfavorable temperature and hydrological regimes during the spawning and early ontogenesis of fish. The short summer feeding period does not allow trout to prepare for successful long wintering, as evidenced by a sharp decrease in the growth rate of fish that have fallen into natural conditions, compared to fish grown in cages. Trout of cage origin obviously do not form stable groups capable of reproducing the species and do not pose a threat to the aboriginal fish population, including Atlantic salmon, whose spawning and a significant part of the life cycle take place on many rivers of the north-eastern European Russia, including the basins of the Severnaya Dvina and Pechora rivers
TAXONOMIC COMPOSITION AND QUANTATIVE INDICATORS OF MACROZOOBENTHOS IN WATER BODIES OF WEST KAZAKHSTAN REGION
Authors: Sarmanov Aybek , Sergaliev Nurlan Khabibullovich , Akhmedenov Kazhmurat Maksutovich , Sultanov Erzhan Sakhypzhanovich , Kashevarov Gleb Sergeevich , Frolova Larisa Alexandrovna
Published: September 2021

The article presents the results of the study of macrozoobenthos communities of six lakes in the West Kazakhstan region in the summer-autumn period: Shalkar, Balykty Sarkyl, Edilsor, Glubinnoye, Prorva and Sulukol. Lakes Prorva and Sulukol are located within the steppe, the lakes Shalkar, Balykty Sarkyl, Glubinnoye - in the semi-desert, Lake Edilsor - in the desert zone. In total, 197 samples of zoobenthos were taken according to generally accepted hydrobiological methods. There are analized the indices of the number and biomass of aquatic organisms in the studied reservoirs. According to the results of the studies carried out, the organisms of 66 taxa from the groups Oligochaeta, Hirudinea, Bivalvia, Gastropoda, Crustacea, and Insecta were found in benthic samples. Of thesethere were found oligochaetes - 2 species, leeches - 1 species, bivalves and gastropods - 3 species each, crustaceans - 4 species and insects - 53 taxa. Among insects, dip-terans (23 taxa, of which chironomids - 18), mayflies, caddis flies, dragonflies, bugs and beetles were distinguished by the greatest species diversity. It was noted that in the composition of benthic communities, diptera larvae dominated in abundance, the main contribution to the biomass was made by bivalve molluscs. Calculations of the Shannon – Weaver index demonstrate a low species diversity of communities for all water bodies. The highest indices of species diversity were noted in Lake Edilsor - 1.64 bit / specimen, the lowest - in lakes Sulukol and Shalkar - 0.6 bit / specimen. and 0.7 bit / copy. respectively. According to the calculations of the saprobity index, lakes Glubinnoye, Prorva and Balykty Sarkyl belong to the ß-mesosaprobic zone, Lake Edilsor (S = 2.72) to the ɑ-mesosaprobic zone, and the indicators of Lake Sulukol (S = 3.8) correspond to the polysaprobic zone. The values of the saprobity indices of the studied lakes lie within the beta-mesosaprobic – polysaprobic zones. By water quality the studied lakes are assessed as moderately polluted and polluted. According to the classification of S.P. Kitaev (2007) the investigated water bodies are assessed as water bodies of medium feeding. The conducted studies have significantly expanded the taxonomic lists of benthic organisms in this region