bluuebunny/crossref_metadata_2025 huggingface dataset:
Obstetric and perinatal aspects of pregnancy and labor in single women
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kurochka V. , Korolyuk N. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: April 2022

A clear tendency to increase the number of pregnancies and childbirth in single women has become a characteristic medical, social and psychological problem in modern obstetrics. Over the past decade, the number of births in single women has doubled in Ukraine. The objective: assess the impact of psychological and social factors on the course of pregnancy and childbirth, the state of newborns in single women. Materials and methods. Conducted clinical and statistical analysis of the subjects, studied the course and complications of pregnancy and childbirth, the state of newborns. The main group – 110 single mothers and their newborns, control group – 110 married mothers and their newborns. Results. The article presents data on the course of pregnancy and childbirth depending on the marital status of women. The average of single women was 29.3±0.5 years, married – 23.7±0.6 years; among the lone 24.5% women are over 30 years old. In 73.6% of women in the main group pregnancy is unplanned, which is 3 times higher than that of the control group. It was detected in 71.8% of single women suffering a somatic anamnesis and 64.5% – burdened gynecological anamnesis, which causes high of placental dysfunction (60%), of the threat of abortion (47.2%). The high cardiovascular diseases (23.6%) and diseases of the genitourinary system (20%) in single women causes a 4 times higher level of preterm labor compared to married (7.2% and 1.8% respectively). In 30% of single women, childbirth was completed by cesarean section, which is 2.8 times higher than married (10.9%). In the main group, fetal distress was found to be 14.9%, which is 1.6 times more often than the control group (9.3%). Maternal traumatism was observed in 55.4% of single pregnant women, which is 2 times that of the control group. Complications of the postpartum period in single mothers are found to be 18.7%, which is 3 times more often than the married ones. Conclusion. Lonely women constitute high-risk groups for the development of obstetric and perinatal complications, due to a number of medical and social causes. Key words: pregnancy and childbirth, single women, perinatal complications.
Assessment of clinical development of chronic pelvic inflammatory diseases in women of reproductive age with chronic uncomplicated pyelonephritis
Authors:   SI «Institute of Urology of the National Academy of Medical Sciences of Ukraine», Kiev, Romashchenko O.V. , Rudenko A.V. ,   SI «Institute of Urology of the National Academy of Medical Sciences of Ukraine», Kiev, Mitchenko N.V. ,   SI «Institute of Urology of the National Academy of Medical Sciences of Ukraine», Kiev, Biloholovska V.V. ,   SI «Institute of Urology of the National Academy of Medical Sciences of Ukraine», Kiev, Yakovenko L.F. ,   Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kiev, Lebed L.A. ,   SI «Institute of Nephrology, National Academy of Medical Sciences of Ukraine», Kiev
Published: April 2022

The objective: to establish clinic microbiological features of the development of chronic pelvic inflammatory diseases (PID) in combination with uncomplicated pyelonephritis in women of reproductive age. Materials and methods. 150 women were examined, including 50 (group I) – with chronic pelvic inflammatory diseases; 50 (group II) – chronic pelvic inflammatory diseases in combination with uncomplicated pyelonephritis, and also 50 clinically healthy women of reproductive age (control group) with the inclusion of clinic microbiological and immunological methods of research. Results. The conducted research has shown that chronic PID in 78.0% of women developed latently (“silent inflammatory diseases of genitals”) and were primary in correlation to uncomplicated pyelonephritis. At the same time, uncomplicated pyelonephritis was clinically characterized by manifest development with the frequency up to 3 times per year, predominantly (in 88.0%) expressed from the 25th till the 5th day of the cycle. It was also established that in the etiological spectre of chronic PID in combination with uncomplicated pyelonephritis only in 18.0% of cases an isolated bacterial infection was observed, while mixt-infection was observed in 82.0% of cases. Chronic PID and uncomplicated pyelonephritis in 64.0% of cases had common etiological spectre of agents, represented predominantly by associations E.coli with mollicutes, Chlamydia, often at the background of increased IgG titers to cytomegalovirus. It was established that chronic PID in combination with uncomplicated pyelonephritis were characterized by credible reduction of protective characteristics of mucous membrane of genitals compared to control (in 42.0% and in 64.0% of patients, respectively), especially in case of U. urealyticum at the background of diagnostically meaningful titers IgG in the blood serum to cytomegalovirus. Conclusion. The obtained results evidence the close relation between sexual and urinary systems during the formation of inflammatory process with the prevalence of the group of etiological factors, peculiarities of clinical development and the necessity of their reflection in the unified context. Key words: chronic pelvic inflammatory diseases, uncomplicated pyelonephritis, diagnostics.
Modern aspects of the laser therapy application in gynecological practice
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Benyuk V.O. , Puchko M.S. ,   Bogomolets National Medical University, Kyiv, Ukraine, Momot A.A. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Dombrovskyi L.E. ,   Bogomolets National Medical University, Kiev
Published: April 2022

The article highlights the latest approaches to the use of CO2-laser in modern gynecological practice. After all, patients with urinary incontinence, urogenital disorders in the menopausal period, vaginal relaxation syndrome, vaginal wall prolapse and scarring of the vulva make the main contingent of aesthetic gynecology offices in Ukraine. The main reasons that lead to the occurrence of these complications include changes in the genital organs during pregnancy and childbirth, the tension of the pelvic floor diaphragm muscles, connective tissue dysplasia, estrogen deficiency and, as a consequence, the loss of collagen and elastin in the tissues of the genital organs. Today, there are a number of techniques that allow the correction of these complications - conservative, surgical, physiotherapy and psychological. The newest method in the treatment of vagina and vulva atrophic is the application of CO2-laser, which is widely used outside of Ukraine. Under the influence of laser in tissues remodeling processes occur as a response to their damage, enhanced synthesis of collagen and elastic fibers. The positive effect of the latest technique is highlighted in the works of Italian researchers. However, in Ukraine, this method is not common, and the experience of its own use is not sufficient, which led to the prospect of further research. Key words: aesthetic gynecology, urinary incontinence, vaginal mucosa atrophy, vaginal wall prolapse, vaginal deformation, CO2-laser.
Features of obstetric and gynecological anamneses in women of postmenopause with intrauterine fluid
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kuzminа А. , Kovaliuk T. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: April 2022

The article presents data on the characteristics of obstetric-gynecological history of postmenopausal women with intrauterine fluid. The objective: is to study whether the obstetric and gynecological history has an effect on the development of intrauterine fluid in postmenopausal women and based on these data to identify a risk group for the development of intrauterine fluid in postmenopausal women. Materials and methods. A prospective study of 130 female patients of the postmenopausal period with intrauterine fluid and with the physiological course of the postmenopausal period was conducted. During the examination of patients, the data of obstetric history were analyzed, while paying attention to the onset of menarche, menstrual dysfunction, the total number of pregnancies and childbirth, infertility. When studying the gynecological history, we studied gynecological diseases for which surgical interventions were performed on the pelvic organs, inflammatory diseases of the uterus and appendages, the complications arising after surgical interventions were evaluated, and attention was paid to the course of the peri and postmenopausal period. Results. As a result of the study, it was found that postmenopausal women with intrauterine fluid had a burdened obstetric history in the form of menstrual irregularities such as hyperpolymenorrhea (16.4%), abortions and spontaneous miscarriages (71.9% and 16.4%, respectively). there was also a high incidence of secondary infertility (5.9%). From the gynecological history in postmenopausal women with intrauterine fluid, a high frequency of inflammatory processes of the uterus and appendages (37.3%), diseases of the cervix (29.8%) and an increased percentage of surgical interventions in this regard are noteworthy: for cervical diseases – 37%, with inflammatory diseases of the uterus – 8.9% (p<0.05). Conclusions. Compared with postmenopausal women with a physiological course of menopause, postmenopausal women with intrauterine fluid have complications in obstetric and gynecological history. Key words: postmenopausal period, intrauterine fluid, obstetric and gynecological history.
Assessment by obstetrician-gynecologists of the level of training of general practitioners–family doctors and family nurses for the provision of obstetric-gynecological medical services: based on the results of a sociological study
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kiev, Shcherbinska O.S. , Slabkyi G.O. ,   Uzhgorod National University
Published: April 2022

The objective: to study the results of an assessment by obstetrician-gynecologists of the level of training of general practitioners –– family doctors and family nurses for the provision of obstetric – gynecological medical services. Materials and methods. During the study using a specially designed questionnaire, 221 obstetrician-gynecologist were interviewed. Results. The paper presents the results of a sociological study among obstetrician-gynecologists on the study of the results of their assessment of the training levels of general practitioners – family doctors and family nurses for the provision of obstetric-gynecological medical services. According to the study, a low assessment by obstetrician-gynecologists of the levels of theoretical and practical training of general practitioners –family doctors and family nurses in obstetrics and gynecology. Conclusion. The results of the study are the basis for the development of a continuing education system for general practitioners –– family doctors and family nurses for the provision of obstetric and gynecological care. Key words: general practitioners–family doctors, family nurses, obstetric and gynecological care, assessment of the levels of theoretical and practical training by obstetrician-gynecologists.
Current Progress on the Responses of Eggplant to Ultra-Low Temperatures during Production
Authors: SHIMIRA Flavien , TAŞKIN Hatıra
Published: April 2022

Cold stress has an adverse effect on eggplant growth and is a yield-limiting factor. Low temperatures are prevalent during early spring cultivation in temperate climates, and they have a negative impact on eggplant growth and development. Temperatures below the eggplant’s optimum growth temperature (22-30ºC) are considered low and detrimental to growth and development. In this review, we described how eggplants respond to moderately low and cold temperatures at different scales. We compiled literature on the current understanding of physiological, cellular responses to cold stress in eggplant as well as the transcriptional regulation during cold stress. Subsequently, we also highlight the genetic and molecular evidence, particularly the function of cold-responsive genes in strengthening cold tolerance in eggplant. Lastly, we covered the role of mineral nutrients and useful microorganisms in alleviating the consequences of cold stress in eggplant roots. Agronomic management practices such as the use of AMF species may mitigate the detrimental effects of low temperature and the enhancement of crop varieties with high yield throughout cold stress.
Holding Out For a Hero(ine): A Postfeminist Analysis of Superhero Stories from the 1980s
Authors: Johnson Lauren Elizabeth
Published: April 2022

This research thesis focuses on the 1980s and how postfeminism in media was established during this period. Postfeminism as an ideology believes that feminism "died," or at minimum completed and no longer functions as necessary, as women seem to have legal equality now. This thesis looks at postfeminism through the lens of superhero stories from the 1980s. Ultimately, the stories presented show how the overall rejection of the ideology of feminism in favor of postfeminism after the "success" of the second wave affected superhero comic culture in America. Additionally, this thesis looks at the inclusion of this ideology around women's rights in the 1980s in a part of pop culture traditionally produced for men. Superhero stories as a medium were more gender-biased toward men in the 1980s because men were the primary consumers of this type of media, so the inclusion of feminism (or the lack thereof) demonstrated how second-wave feminism and postfeminism impacted the presentation to several groups, including those that were not necessarily affected by these movements.
«Власть традиций»: неотрайбалистское осмысление политики в республиках Дальнего Востока России
Authors: Михалева Анастасия Анатольевна
Published: April 2022

В настоящее время два российских дальневосточных региона – Якутию и Бурятию – объединяет растущая тенденция использования категорий неотрайбализма в политическом дискурсе. Это интересное явление, поскольку речь идет не просто об использовании понятия «политический клан», а об отсылках к местным культурным традициям. Родоплеменная идентичность как политический фактор может не осуждаться, а поощряться. Истоки этого явления обычно ищут в местной специфике, в описанных антропологами и этнографами культурных практиках. Данное исследование – попытка продемонстрировать, что язык неотрайбализма современен, он появился в ответ на текущие запросы, а одну из главных ролей в его становлении и поддержании играет государство. Работа основана на анализе различного контента, однако ее цель – не описать язык неотрайбализма, а понять истоки его существования. Изучение ситуации в двух регионах дало возможность сопоставить полученные данные и вписать практику использования неотрайбалистского языка в социально-политический контекст. Органы власти выступают одним из основных акторов, репрезентующих неотрайбалистские смыслы, которые являются частью более общего дискурса неотрадиционализма. Создаваемый контент обозначает трайбализм как часть ценных местных традиций. Массмедиа подхватывают и тиражируют идею племенной структуры местного общества, поскольку эта тема – рейтинговая. В результате уже само государство рассматривается в неотрайбалистском ключе. Популярность этой модели описания политики напрямую зависит от того, насколько власти активно поддерживают неотрадиционалистский дискурс.
«Я волком бы выгрыз бюрократизм»?
Authors: Неретина Светлана Сергеевна
Published: April 2022

В рецензии анализируется сборник работ разных лет под общей редакцией доктора философских наук, доктора политических наук, основателя Южно-Российской школы политических наук профессора В.П. Макаренко, 75-летию которого посвящен один из разделов сборника. Три раздела сборника («Круглый стол, проведенный на базе журнала “Вопросы философии”»; «Тридцать лет спустя: сферы властно-бюрократической активности»; «Методологическая рефлексия») являются результатом работы международной конференции, целью которой была разработка концепции бюрократии, методов ее переплетения с авторитаризмом, утвердившегося в России, по мнению большинства авторов, после крушения советской власти, а также выявление способов становления демократизма. Поставлены такие проблемы, как соотношение бюрократии, авторитаризма и будущего демократии в России, бюрократии и подмены политики управлением, бюрократии и вождизма, бюрократии и собственности, бюрократии и ее связей с российской провинцией. Рассмотрены стереотипы бюрократического сознания как опасная патология, изменения, связанные с пандемией. Аналитические главы сборника имеют острую публицистическую направленность, рассчитаны на широкие слои читателей. Почти все авторы сборника связывали начало авторитарного правления с недостаточностью демократического образования, констатировав при этом, что для существования эффективно работающей бюрократии требуется наличие среднего сословия, которое обладало бы правовым сознанием; помимо этого, необходима борьба не столько с бюрократией, сколько с бюрократизмом. Обнаруживаются истоки современного российского бюрократизма и авторитаризма в марксистской теории. Вводятся понятия (авторитарная бюрократия, ноократия, ветократия, деятельность для деятельности, социальные разумные системы и др.), многие из которых, однако, не получили развития. Анализу подверглось одно из них – «номенклатура». Вместо старого его определения, данного М.С. Восленским и понимаемого как «перечень руководящих должностей, замещение которых производит не начальник данного ведомства, а вышестоящий [партийный] орган, и соответственно перечень лиц, которые такие должности замещают или находятся в резерве для их замещения», автор одной из статей сборника С.Д. Хайтун предлагает связывать номенклатуру с привилегиями чиновников, с понятием социальных разумных систем, которые (подобно «классовому сознанию», «коллективному бессознательному» и пр.) подчиняют себе интересы индивидов, координируют их деятельность в собственных интересах и создают коллективную собственность чиновников. Эта собственность не является ни частной, ни государственной, а представляет собой неизвестную ранее форму собственности, которая играет, однако, системообразующую роль в государстве.
Цифровизация российской средней школы: отдача и факторы риска
Authors: Попов Дмитрий Сергеевич , Стрельникова Анна Владимировна , Григорьева Екатерина Александровна
Published: April 2022

Цифровизация школ в восприятии людей зачастую связана лишь с техническим переоборудованием: с приобретением новых компьютерных средств или разработкой общешкольных онлайн-программных продуктов («порталов»). Однако техническая трансформация школы последних десятилетий предполагает весьма глубокие и серьезные изменения для профессии учителя и социальных отношений в школе. В статье на основе международных сравнительные данных программы PISA показано, что существующие цифровые школьные практики в европейских странах и в России не приводят к повышению измеренных компетенций учащихся в разных предметных областях. В литературе высказывается гипотеза, что расширенный доступ к цифровым устройствам (включая ноутбуки, планшеты, мобильные телефоны и т. д.) сам по себе не ведет к развитию и совершенствованию образовательной практики. В статье предложены результаты исследования российских учителей, направленного на изучение качественных характеристик цифровых изменений в школах. В исследовании выявляется отношение учителей к процессу цифровизации, оцениваются их существующие профессиональные практики, показаны опасения и ожидания от возможной институциональной трансформации и трансформации профессии учителя. Обнаружено, что цифровизация в российской школе направлена на поддержание и воспроизводство прежних доцифровых практик, а не на развитие новых.
Гражданское общество в информационно-цифровую эпоху: проблемы трансформации и адаптации
Authors: Туманова Анастасия Сергеевна , Сафонов Александр Александрович
Published: April 2022

В статье рассматривается воздействие информационно-цифровой эпохи на гражданское общество. Авторы показывают, что в условиях цифровой коммуникационной среды традиционные институты, практики и ценности гражданского общества трансформируются, классические представления о последнем, созданные видными социальными и  политическими теоретиками (от Алексиса де Токвиля до Юргена Хабермаса), перестают работать безоговорочно, а пространство публичной сферы основательным образом переформатируется. Исследование сфокусировано на теориях и эвристических прогнозах влиятельных западных обществоведов XX столетия: Мануэля Кастельса, Юргена Хабермаса, Никласа Лумана и Роберта Патнэма. Подобный подход представляется продуктивным потому, что на заре информационно-сетевого общества они пытались заглянуть в будущее, и многое из того, что они предсказывали, осуществилось. Помимо этого, данный подход позволяет составить целостное представление о воздействии сетевых коммуникаций на третий сектор. Обобщение теоретических подходов к проблеме адаптации третьего сектора к цифровой среде представляет собой одну из первых попыток теоретического синтеза представлений о векторе развития публичной сферы под влиянием вызовов современности. Авторы приходят к выводу, что преобразование гражданского общества в информационно-цифровую эпоху носит противоречивый характер. С одной стороны, публичная сфера демонстрирует в открытой коммуникационной сетевой среде способность к скорой мобилизации и адаптации, к расширению своего влияния и преодолению национальных границ. С другой стороны, сетевое общество усиливает фрагментацию третьего сектора, дает импульс к развитию проектных акций, предполагающих взаимодействие в сетях для достижения тех или иных краткосрочных целей, приглушая вместе с тем многие традиционные формы самоорганизации и практики гражданского участия. В статье анализируется диалектика отношений гражданского общества и государства, выражающаяся в  стремлении гражданских активистов к расширению своего присутствия в сети и сокращению контроля со стороны государства, а также в увеличении возможностей государства для осуществления контроля над гражданами и публичной сферой.
Когда мэры против: факторы муниципальной автономии в условиях централизации
Authors: Шевцова Ирина Константиновна , Гилев Алексей Владимирович , Завадская Маргарита Андреевна
Published: April 2022

В статье представлены объяснения вариативности муниципальной автономии в контексте централизованного государства. Политическая и экономическая централизация привели к тому, что муниципалитеты постепенно стали частью исполнительной вертикали. Это задает ожидание, что муниципалитеты будут проводниками политических курсов вышестоящих властей. Вместе с тем некоторые российские муниципалитеты демонстрируют если не сопротивление им, то, по крайней мере, разную скорость и качество их реализации. Авторами делается попытка ответить на вопрос, почему некоторые российские муниципалитеты сохраняют способность противостоять политическим курсам вышестоящих властей в условиях политической и экономической централизации. В статье представлен теоретический обзор шести факторов, которые формируют стимулы для проявления автономии в российских муниципалитетах. Эти факторы подкреплены материалами интервью с муниципальными служащими и региональными чиновниками, а также материалами СМИ. Авторы утверждают, что различия в проявлениях местной автономии в контексте централизации связаны с меньшей зависимостью муниципалитетов от региональных бюджетных денег, сохранившимися прямыми выборами глав или ситуацией «двойной подотчетности» при процедурах назначения, оппозиционностью мэров или же, наоборот, их значимостью для «политической машины», степенью укорененности мэров в территории и качеством неформальных связей с региональными чиновниками, конкуренцией экономических акторов и зависимостью мэров от местного бизнеса, а также конкуренцией между главой и местным советом.
Стратегии сохранения и отмены прямых выборов глав муниципальных образований в России
Authors: Минаева Элеонора Юрьевна
Published: April 2022

По сравнению с выборами назначение как механизм контроля элит имеет ряд преимуществ для обеспечения их сплоченности и поддержки действующего режима. В связи с этим большинство российских региональных властей, получивших возможность самостоятельно определять «дизайн» исполнительной власти на местном уровне после реформы местного самоуправления в 2014–2015 гг., оказалось нацелено на замену прямых выборов руководителей муниципалитетов фактическими назначениями. Тем не менее отмена прямых выборов глав муниципалитетов не всегда возможна и выгодна региональной власти. На примере нескольких муниципалитетов Амурской области и Республики Бурятия с опорой на материалы интервью данная работа показывает, что ключевым условием, позволяющим заменить прямые выборы мэров новой конкурсной процедурой, является лояльность муниципального совета, которая обеспечивается за счет доминирования партии «Единая Россия». В этом случае фактическое назначение используется или для того, чтобы продлить политическое «выживание» действующего лояльного главы, который потерял способность переизбраться электоральным путем, или для устранения нелояльного инкумбента. Исключения составляют мэры с сильными «политическими машинами»: они по-прежнему могут рассчитывать на сохранение выборов, если удовлетворяют интересы региональной администрации. Оппозиционные муниципальные советы препятствуют замене выборов назначениями, поскольку по новой конкурсной процедуре избрание кандидатов от оппозиционных партий практически невозможно. В этих условиях региональной администрации также проще поддерживать выборную модель, поскольку она делает мэра независимым от оппозиционного совета, но в то же время дает возможность региональной власти кооптировать его ресурсы в единую вертикаль.
Investigation of the relationship between Androgen Receptor Gene CAG Repeat Polymorphisms and Turkish gifted students’ science attitudes
Authors: KIZILBAY KAYA Merve , POLAT Fikriye
Published: April 2022

This study aims to examine the AR gene CAG polymorphisms of gifted students, and to determine whether there is a relationship between this gene region and students' attitudes towards science. The research was conducted with randomly selected gifted students (N = 100) and normally developing students (N = 100) studying at the 5th grade level in Kocaeli, Turkey during the 2017-2018 and 2018-2019 school years. In order to determine students' attitudes towards science, science and technology lesson attitude scale was applied. According to the results of the study, while there was no significant difference in terms of "enjoyment" and "social content of science" from the science and technology lesson attitude scale factors, it was found that there was a statistically significant difference in favor of gifted students from the "scale total scores" and "desire to learn" factors (p<0,05). In the genetic dimension of the study, no statistically significant difference was found between the two groups in AR gene CAG polymorphisms. In the whole sample, there was no significant relationship between the AR gene CAG polymorphisms and the "scale total score" values.
PCR mixture and condition (2X SUPERGREEN PCR MASTER MIX) v2
Authors: Huang Yin-Tse
Published: April 2022

PCR mixture and condition (2X SUPERGREEN PCR MASTER MIX)
[RETRACTED] Apple Keto Gummies Australia - Fake` Reviews 2022, Does it work? v1
Authors: not provided health
Published: April 2022

[RETRACTED]

Apple Keto Gummies Australia is a weight loss supplement that aims to treat the root cause of stubborn fat and accelerate ketosis, that is burning fat instead of carbs, without posing any threat to your health. It comprises natural ingredients, with beta-hydroxybutyrate (BHB) being the key component. Apple Keto Gummies come in the form of gummies that are easy to swallow and digest. buy now - https://www.topofferlink.com/HXP6CGZ/9RX9KCZ/
[RETRACTED] Keto extreme fat burner clicks v1
Authors: not provided surajchandprakash
Published: April 2022

[RETRACTED]

It puts the body proper right into a faster ketosis technique and burns all the undesirable fats. It uses fats and leaves the carbs for muscle boom.
Prostat Kanseri Kemik Metastazına Radyoterapi Uygulanan Hastalarda Sağ Kalımı Etkileyen Faktörler
Authors: MENTEŞ Selahattin , KARACA Feryal , KESKİN Sıddık
Published: April 2022

Amaç: Bu çalışmada, prostat kanserlerinde metastatik kemiğe radyoterapi uygulanan hastalarda sağ kalım üzerine etkili olabileceği düşünülen faktörlerin karşılaştırılması amaçlanmıştır.

Gereç ve Yöntemler: Prostat kanserinin kemik metastazı nedeniyle radyoterapi almış olan 92 hasta çalışmaya dahil edilmiştir.

Bulgular: Yetmiş yaşından küçük hastalarda %57.1 oranında ölüm gözlenirken, >70 yaş hastalarda bu oran %74 olarak belirlenmiştir. Bu değerlerin karşılaştırılmasında her ne kadar istatistiksel olarak anlamlı fark görülmese de >70 olan hastaların ≤70 hastalara göre ölüm riskinin 2.135 kat daha yüksek olma

eğiliminde olduğu gözlenmiştir (p>0.05). Visseral organ metastazı ile birlikte kemik metastazı olan hastalarla, yalnız kemik metastazı olan hastaların sağ kalımı karşılaştırıldığında istatistiksel olarak anlamlı sonuç bulunmuştur (p
Influência do Estilo de Liderança e da Subordinação no Julgamento e Tomada de Decisão do Auditor Interno
Authors: Da Silva Alini , Haveroth Juçara , Roberto da Cunha Paulo
Published: April 2022

Objetivo: Analisar o efeito do estilo de liderança e da subordinação no julgamento e tomada de decisão do auditor interno.Metodologia: A pesquisa possui enquadramento metodológico como descritiva, quase-experimento e quantitativa. O caso experimental foi pautado na tomada de decisão de auditor interno em reportar um relatório de recomendações sobre irregularidades realizadas pelo setor financeiro, sendo que o auditor é subordinado ao setor financeiro que realizou as irregularidades. Para tanto, foram apresentados aos participantes auditores, dois estilos de liderança do diretor financeiro, sendo o estilo autocrático e democrático, como também diferentes opiniões do diretor financeiro sobre o relatório de recomendações, para caracterização da subordinação.
Resultados: Os resultados apontaram que os auditores internos tendem a reportar em menor grau o relatório de recomendações quando seu superior é um líder autocrático, conforme apontado pela literatura. Além disso, diferenças de tempo identificadas para tomada de decisão, sugerem que o estilo de liderança pode ter influenciado a tomada decisão de reporte, visto que, quando o superior possui perfil de liderança autocrático, o auditor interno tende a demandar maior tempo de tomada de decisão.
Contribuições: Contribuiu por demonstrar, com evidências empíricas aos órgãos de regulação, governança corporativa de empresas e demais interessados, sobre a perda de independência de trabalho do auditor interno, quando subordinado a diretores financeiros com estilos de liderança que pouco contribuem para a transparência das informações. Essa situação pode ser considerada um risco à qualidade dos controles internos e, por vezes, à qualidade das demonstrações financeiras.
Determinantes para Aprovação do Pacote de Remuneração dos Executivos por Parte dos Acionistas
Authors: Rissatti Jean Carlo , Borba José Alonso , Martins Dias Maragno Lucas , Paulo Edilson
Published: April 2022

Objetivo: Analisar os fatores determinantes para aprovação do pacote de remuneração dos executivos pelos investidores institucionais das empresas brasileiras listadas na Brasil, Bolsa, Balcão (B3).Método: A pesquisa foi realizada sobre 771 votos de acionistas nas deliberações das Assembleias Gerais Ordinárias e Extraordinárias (AGO/E), no período de janeiro a abril de 2019, das firmas listadas na B3. A coleta de dados foi realizada manualmente e buscou, nos formulários de referência, posições acionárias, propostas das administrações, atas das assembleias gerais e mapas finais de votação analítico e sintético. Os dados obtidos foram analisados por meio de regressões logísticas.
Resultados: A remuneração total dos executivos está positivamente relacionada ao voto de aprovação do pacote por parte dos acionistas controladores, o que indica um alinhamento entre o principal-agente. Ainda, as demais hipóteses demonstraram um desalinhamento entre controladores e não controladores e que a dissidência reduz a probabilidade de aprovação dos pacotes de remuneração, o que aponta para um conflito de interesses entre principal-principal. Outro resultado da pesquisa indicou que há um excesso de remuneração por meio de pagamentos baseados em ações, o que pode indicar expropriação de recursos por esse tipo de remuneração.
Contribuições: Este trabalho contribui para o desenvolvimento do mercado de capitais brasileiro e seus acionistas, gestores e para a transparência das empresas.
Efeitos da Incerteza da Política Econômica no Caixa das Empresas Brasileiras
Authors: Dias Souza Gustavo Henrique , Batista Alexandre Teixeira Norberto , Cunha Jacqueline Veneroso Alves da
Published: April 2022

Objetivo: Investigar os efeitos da incerteza da política econômica sobre o caixa e a folga financeira das empresas de capital aberto listadas no mercado acionário brasileiro.Métodos: Utilizando como medidas de incerteza o Economic Policy Uncertainty Index (EPU) e o Indicador de Incerteza da Economia – Brasil (IIEBr) e como medidas de caixa o próprio caixa e equivalentes e a folga financeira, este estudo usou estimações por GMM - Sistêmico, cuja aplicação pode atenuar o problema da endogeneidade, com dados trimestrais de 152 empresas com ações negociadas na Brasil, Bolsa, Balcão (B3), no período de 2010 a 2020.
Resultados: De forma geral, foram encontradas evidências de que a incerteza da política econômica está positivamente relacionada ao nível de caixa das empresas da amostra, indicando que as empresas retêm mais caixa quando a incerteza aumenta. Análises adicionais sugerem que a incerteza da política econômica também influencia o caixa futuro das firmas. Os resultados indicam, ainda, um resultado mais acentuado quando utilizado o IIEBr em comparação com o EPU, consistente com diferentes formas de cálculo das métricas.
Contribuições: O estudo tem implicações para a literatura e para as empresas ao demonstrar o papel das reservas de caixa das empresas no mercado brasileiro na mitigação do efeito adverso da incerteza da política econômica.
Incerteza Econômica e Nível de Agressividade Tributária das Empresas Listadas na B3
Authors: Marques Vagner Antônio , Zucolotto Anderson de Freitas , Guzzo Acerbe Lorian , Zanoteli Eduardo José
Published: April 2022

Objetivo: Analisar a associação entre o ambiente de incerteza econômica e o nível de agressividade tributária das empresas brasileiras listadas na B3.Lacuna: Diferente da literatura nacional já existente, o presente estudo analisa o efeito do ambiente econômico recessivo combinado com o nível de agressividade tributária das empresas listadas.
Método: A pesquisa, de natureza descritiva, documental e com abordagem quantitativa, analisou dados do período de 2013 a 2018 das 252 empresas que estavam listadas na B3 até 31/12/2018 por meio da estatística descritiva, teste de diferença entre as médias e análise de regressão com dados em painel. Os dados foram coletados nos sítios eletrônicos da COMDINHEIRO e do IPEADATA, e foram analisados por meio do software Stata 16.
Resultados: Os resultados demonstraram que não houve uma associação positiva entre a agressividade tributária e o ambiente de incerteza econômica, porém, observou-se que este ambiente modera o efeito das determinantes da agressividade tributária. Estes resultados são robustos para heterocedasticidade, autocorrelação e diferentes proxies de agressividade tributária.
Implicações: As conclusões contribuem com elaboradores de políticas econômicas, reguladores, auditores e analistas de mercado, bem como sinalizam que a carga tributária tem um efeito indireto sobre a adoção de práticas de planejamento tributário mais agressivas, o que pode funcionar como sinalizadores de risco de evasão tributária e/ou litígios futuros.
Efectos del Entrenamiento de Fuerza Pediátrico sobre parámetros de salud en niños: una revisión sistemática
Authors: Valle Muñoz Víctor Manuel , Vanaclocha Amat Pepe , Villa-González Emilio
Published: April 2022

La inactividad física, cada vez más frecuente entre los niños y las niñas, está asociada a diferentes problemas de salud, entre ellos, la dinapenia pediátrica, caracterizada por bajos niveles de aptitud muscular. Esto suscita la necesidad de implantar programas de Entrenamiento de Fuerza Pediátrico (EFP) para mejorar la salud en esta población. Este trabajo tiene como principal objetivo realizar una revisión sistemática sobre las principales investigaciones que abordaron los efectos de un programa de EFP sobre diferentes parámetros de salud en niños y niñas de 6 a 13 años. Se ha seguido el protocolo PRISMA utilizándose 5 bases de datos (Web of Science, Scopus, Sportdiscus, PubMed y ERIC). Los resultados obtuvieron un total de 587 artículos, de los cuales 13 cumplieron los criterios de inclusión y exclusión. Tras el análisis de los 13 artículos, los resultados muestran que el efecto de las intervenciones de EFP en niños mostró mejoras sustanciales en diferentes parámetros antropométricos (composición corporal, IMC, circunferencia de la cintura y densidad mineral ósea), y en menor medida en variables fisiológicas (presión arterial y perfil lipídico) y psicológicas (autoconcepto y autoestima). Se concluye que los programas de EFP parecen establecerse como un tratamiento no farmacológico adecuado para mejorar determinados parámetros de salud antropométricos, precisando más investigación para determinar el efecto sobre variables fisiológicas y psicológicas.
Investigating the Optimal Design Variables of Concrete Slabs with Impact Resistance by Development a Multi-Objective Model to Save Cost-Time of Construction
Authors: Al Kulabi Ahmed Kamil , Al Zahid Ali Adnan
Published: April 2022

Globally, construction industry plays a key role in development of an economy of any country. On the other side, construction projects suffer extensive delays and cost overruns exceeding by that the budgeted money and the estimated time. Therefore, adopting techniques like optimization technique in construction media became a necessity for preventing the actual cost and execution time of projects from exceeding the planned cost and estimated time, respectively. Since, concrete is the most essential construction and the most used material in construction projects construction where it influences extremely gross domestic products of numerous nations in the world, a multi-objective mathematical model with mixed linear and binary constraints is developed to specify the optimal solution of differently designed concrete slabs to impact loads. Eight concrete slabs had various design parameters, such as concrete thickness, steel fiber ratio, reinforcement ratio, and steel stiffener thickness are used in this study. The mathematical model comprised two objective functions: minimization cost and time, and had a number of constraints like concrete ingredients, load, deflection, and weight. The outputs of the developed model revealed a variety of slab design combinations with different cost, time, and deadloads depending on the limitations of serviceability loads.
Optimal Design of a Proportional-Derivative State Feedback Controller Based on Meta-Heuristic Optimization for a Quarter Car Suspension System
Authors: Al-Khazraji Huthaifa
Published: April 2022

This paper presents a Proportional-Derivative State Feedback (PDSF) controller approach to design an active suspension system for quarter car. The objective of the PDSF controller is to eliminate the effects of road disturbances to achieve ride comfort of the driver and passengers. Finding the optimal feedback gain matrix of the PDSF controller is formulated as an optimization problem. Then, two meta-heuristic optimizations named Bees Algorithm (BA) and Grey Wolf Optimization (GWO) are employed to optimize the feedback gain matrix of the PDSF controller based on the Integral Time of Absolute Error (ITAE) index. The results show the superiority of the BA-based PDSF controller in terms of reducing the ITAE index in comparison with the results obtained from GWO based PDSF.
Kinematic and Singularity Analysis of 10 DOF Lower Body of Humanoid Robot
Authors: Bharadwaj Deepak , Mishra Natraj , Pathak Maheshwar
Published: April 2022

With the existing kinematic configuration of a humanoid robot, fast turning is the main issue encountered. The joint orientation of the lower body of a humanoid robot does not allow the system to move fast. The first joint of the existing setup is started with the rotary joint vertically up z-direction. A change in the joint orientation had been proposed for the kinematic configuration of the humanoid robot. The first joint in this proposed work is the revolute joint along the x-direction of movement. Forward and inverse kinematics were obtained for the maximum value of the reach of the leg in the environment. Jacobian was described for every joint. Singularity posture was obtained at the location.
Study of Genome, Vaccine and Probable Anti Viral Drugs to Save the World From the Capture of SARS-CoV-2: A Mini-Review
Authors: Pradhan Arun Kumar , Arakha Manoranjan , Sahoo Binay Kumar , Bhattacharya Debapriya
Published: April 2022

The coronavirus disease 2019 (COVID-19) is a single-stranded RNA (+) virus and causes infectious disease by the viral strain "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). Now, COVID-19 has become pandemic, and there are neither potential vaccines nor drugs discovered. Its RNA contains genes for structural (S, E, M, N) and non-structural proteins (PLpro, 3CLpro, RdRp, Hel). Interaction between the S protein of SARS-CoV-2 and the ACE 2 receptor of the host cell plays a vital role in the entry of the virus into the cell. Favipiravir, ribavirin, remdesivir, galidesivir, lopinavir, ritonavir, chloroquine, and hydroxychloroquine are the few effective drugs against SARS-CoV-2. Live attenuated virus (mutant MERS-CoV and SARS-CoV or recombination with another live attenuated virus) can act as vaccine platforms against SARS CoV-2 along with DNA vaccine and subunit vaccine.
Neurological Manifestations in Critically Ill COVID-19 Patients
Authors: Amoozadeh Laya , Beigmohammadi Mohammad Taghi
Published: April 2022

Patients with COVID-19 frequently experience neurological symptoms. Headaches and dizziness are common but non-specific symptoms. Both peripheral and central nervous systems can be impacted in severe stages. We focused on the neurological manifestations of COVID-19 patients in critical care. A cohort study evaluated the acute neurological manifestations in 204 patients admitted to intensive care units (ICU) tertiary Imam Khomeini hospital complex, Tehran, Iran. Patients with positive COVID-19 tests and severe clinical symptoms in both sexes, older than 16 years, were included in the study. Two groups of patients with positive or negative neurologic complications were compared by chi-square or Fisher exact test for categorical variables. The differences in continuous variables between the two groups were investigated using an independent sample t-test. The Kolmogorov-Simonov test was used to verify the normality assumption. A P less than 0.05 was considered statistically significant. The study included 204 individuals (130 males and 74 females) out of 270 ICU patients. Ninety (44.1%) patients were discharged, while 114 (55.9%) died. Overall, 17 (8.3%) patients had neurological complications, while 187 (91%) did not (P=0.005). The two groups did not have significantly different mean age (P=0.325) and sex (P=.793). The ventilation support was significantly different in the two groups (P=0.002). The death group had a higher incidence of loss of consciousness (P=0.003). COVID-19 causes neurological symptoms, especially during the inflammatory phase, and clinicians should be alert for neurological issues.
Role of Magnetic Resonance Imaging of Brain in Evaluation of Pediatric Seizure Disorder
Authors: Soujanya BS , Shetty KM Dhrithiman , Raghuraj Uppoor , Shenoy Vijaya
Published: April 2022

Seizure disorder in children is commonly seen in clinical practice and in the assessment of these patients. Magnetic Resonance Imaging (MRI) is found to be the ideal and first imaging modality of choice for pediatric seizure disorder because of lack of radiation exposure. This work aims to assess the role of MRI of the brain in the evaluation of pediatric seizure disorder. Before undergoing MRI, all of the patients received EEG to detect the epileptogenic center. On the superconductive 1.5-Tesla Siemens Avanto Magnetom MR system, patients underwent a brain MRI scan. Percentages and proportions were used in the statistical analysis. Around 70% of children with seizures were found to be controlled by the use of a single antiepileptic drug (AED). Electroencephalogram (EEG) findings were abnormal in 82% of patients. The MRI findings were normal in 45 patients (45%) and abnormal in 55 patients (55%). The common abnormalities were gliosis (45.4%), periventricular leukomalacia (12.7%), neurodegenerative changes in white/grey matter (7.3%), focal cortical dysplasia (FCD) (7.3%), arteriovenous malformations (AVM) (7.3%), polymicrogyria (5.5%), mesial temporal sclerosis (MTS) (5.5%), abnormal spectroscopy (3.6%), space-occupying lesion (SOL) (3.6%) and megalencephaly (1.8%). Our study showed about 55% of children with seizures had MRI abnormalities and common abnormalities were gliosis and periventricular leukomalacia. Improvements in perinatal care, hygiene, and socio-economic status can help in reducing the incidence and thus morbidity associated with a seizure disorder. Thus, MRI plays a pivotal role in the workup of pediatric patients with a seizure disorder.
The Effect of the Door to Needle Time of Streptokinase Administration on the Left Ventricular Function and Thrombolysis in Myocardial Infarction (TIMI) Flow Grade in Patients With Anterior Myocardial Infarction: A Single-Center, Prospective Follow-Up stud
Authors: Ghasemi Reza , Moghaddam Saeideh Imani , Ramezani Fatemeh , Yaghubi Mohsen
Published: April 2022

Early administration of thrombolytic agents is the standard treatment and crucial for the outcome for patients presenting with acute myocardial infarction (MI). This study was conducted to evaluate the door to needle time of streptokinase administration and the left ventricular function in patients with anterior MI. This study was a prospective, single-center study on participants with anterior MI who were received streptokinase and non-streptokinase groups. After administration of streptokinase, QTc was measured in hyper-acute, acute, and recent phases of anterior MI in the case group and compared with acute and recent phases in the control group. The left ventricular function in 5 and 42 days after emergency department arrival was measured and compared in two groups. The data were analyzed by descriptive statistics method and variance analysis in the SPSS software, version 22. The level of significance was considered to be 0.05. Among 87 participants (45 streptokinases, 42 non-streptokinase), there was a significant relationship between the door to needle time in patients who received streptokinase in 1 hour (P=0.000), 3 hours (P=0.007), and 6 hours (P=0.016) after onset the chest pain and an ejection fraction of the patients in 5 days after hospitalization. Also, there was a significant relationship between ejection fraction in 5 days (P=0.000) and 42 days (P=0.000) of administration streptokinase and door to needle time. Reduction of the door to needle time after anterior MI has significant effects on QTc and incidence of threatening arrhythmia.