bluuebunny/crossref_metadata_2025 huggingface dataset:
O uso de aspirina para prevenção secundária de infarto agudo do miocárdio
Authors: Lucena Gustavo dos Santos Jardim , Silva Vinicius Melo , Jadjiski Yuri de Lima , Teixeira Adryan Gustavo Barbosa , Rocha Marcos da Silva , Lucena Juliana Balla , Medeiros Larissa Ávila , Nunes Bárbara Lopes Costa , Rocha Otávio Augusto Rodrigues Nery da , Rodrigues João Paulo Maia
Published: August 2024

Objetivo: Investigar o uso da aspirina na prevenção secundaria de infarto agudo do miocárdio. Métodos: Trata-se de uma revisão integrativa, com artigos publicados entre 2019 e 2024 nas línguas portuguesa, inglesa e espanhola e com o conteúdo disponibilizado na íntegra. Como pergunta norteadora, utilizou-se: “O uso de aspirina para prevenção secundário de infarto agudo do miocárdio é recomendado?”. A pesquisa bibliográfica foi realizada nas bases de dados MedLine, Literatura Latino-Americana e do Caribe em Ciência da Saúde (LILACS), e Índice Bibliográfico Español em Ciencias de la Salud (IBECS) durante os meses de abril e maio de 2024. Foram utilizados os Descritores em Ciências da Saúde (DeCS): “Aspirin”, “Infarction” e “Secondary Prevention” com o operador booleano “AND”. Resultados: As 12 publicações enquadradas nos critérios de inclusão e exclusão revelam que o uso de aspirina é recomendado para prevenção secundaria de infarto agudo do miocárdio, juntamente com os inibidores de P2Y12. Considerações finais: O uso de aspirina para prevenção secundaria de infarto agudo do miocárdio é essencial e quando associado a um inibidor de P2Y12 pode potencializar esse efeito protetor para os pacientes submetidos à ICP.
An observational study of auditory-evoked potential mismatch negativity response in individuals at high genetic risk for schizophrenia
Authors: Jangde Rakesh Kumar , Umesh Shreekantiah , Goyal Nishant , Khess Christoday RJ
Published: August 2024

Objectives:

This study presents a novel approach by investigating the abnormal mismatch negativity (MMN) found during response to auditory-evoked potential (ERP) in schizophrenia (SZ) patients. Our unique focus is on the genetic high-risk (GHR) for SZ, comparing it with healthy controls (HC). In addition, we aim to illuminate the interrelationship of MMN with socio-occupational functioning in the GHR group, a novel aspect of our research.

Material and Methods:

We conducted this study with a rigorous methodology, ensuring the reliability and validity of our findings. Thirty first-degree relatives of SZ patients (GHR) who met the inclusion and exclusion criteria were recruited by purposive sampling and compared with thirty HCs. We collected sociodemographic and clinical data from all study participants, which were assessed by the Family Interview of Genetic Studies. GHR was evaluated for current socio-occupation functioning using the Social and Occupational Functioning Assessment Scale (SOFAS). All the participants underwent 128-channel electroencephalographic recording using an auditory-evoked responses paradigm. The MMN was calculated at the frontal electrode clusters, ensuring accurate and reliable data collection.

Results:

The study revealed a statistically significant difference in frontal MMN latency between GHR and HC. Moreover, a positive relationship was noted between the SOFAS score and MMN amplitude, and a negative relationship was found between the latencies at the frontal region.

Conclusion:

Our research has made a significant breakthrough in understanding SZ. Our findings reveal that individuals with a genetic susceptibility to SZ exhibit a unique response in a particular test known as MMN. This test measures the automatic auditory change detection mechanism, which detects minor alterations in the acoustic environment and is referred to as MMN. This newfound insight could prove instrumental in developing more effective diagnoses and treatments for SZ.
Termite gut microbiome being a rich source of potential lignocellulolytic bacterial strains
Authors: Yadav Poonam , Singh Shiv Ram , Trivedi Mala , Singh Sujeet Pratap
Published: August 2024

A study was carried out to identify prospective cellulose degrading bacteria isolated from termite gut collected from various agriculture sites. Eight of the bacterial isolates displayed a very distinct zone of clearing on CMC (Carboxylmethyl cellulose) agar media after staining with 1% Congo red, indicating that they may have cellulose degrading ability. On a CMC agar plate, CRDB6 had the largest colony diameter (3.08 cm) as well as clear zone diameter (0.96 cm), however CRDB 1 has maximum cellulolytic activity (1.45 cm) followed by CRDB5 and CRDB6 (1.33 cm and 1.28 cm) respectively. CRDB3, CRDB4 and CRDB9 showed Gram negative reaction among crop residue degrading bacterial isolates, while the remainder showed Gram positive reaction. The morphological characteristics of the bacteria isolates, such as colony shape, elevation, margin, colour and opacity, differed. Isolates CRDB6 produced highest β-glucosidase activity (12.66 m L-1) followed by CRDB1 (12.20 mg m L-1) and CRDB5 (10.21 m L-1) in Luria broth culture. Indole acetic acid production (with tryptophan) was greater in CRDB1 (389.33 mg/ml), CRDB6 (356.9 m L-1) and CRDB3 (315.96 m L-1) while as P-solubilization potential was peaked in CRDB6 (2.41 m L-1) followed by CRDB4 (1.76 m L-1) and CRDB3. Overall, isolate CRDB6 exhibited the highest cellulolytic activity as compared to rest of the bacterial isolates. These results will help in preparing bacterial consortia for the management of crop residues.
Assessment of Interleukin 6 and Interleukin 8 in type 2 Diabetic patients recovered from SARS_COV_2 induced Covid 19 infection in Kirkuk City, Iraq
Authors: Muhammad Fatma Mustafa , Pambuk Chateen I. Ali
Published: August 2024

This study aimed to measure the levels of interleukin 8 and interleukin 6 in type 2 diabetic patients who were infected with Covid-19 and recovered and to compare them with diabetic patients who did not have Covid-19 and healthy people. The patients were divided into three groups. The first group was for diabetic patients recovering from Covid and the total number of samples included 41 samples. In addition, 18 samples were taken from diabetics who were not infected with Covid-19 as a second group and a third group was also taken with the number of samples as 25 from healthy people not infected with the Corona virus or diabetes or any other disease. For the period from September 2022 - February 2023, their ages ranged between 39-64 years. Samples were obtained from patients attending private clinics and hospitals in Kirkuk Governorate. Patients were diagnosed with diabetes according to WHO criteria. This study excluded patients with hypertension, cardiovascular disease, kidney disease, smokers and those taking any other treatment except diabetes treatment: metformin and glimepiride. The results of the current study with regard to blood sugar level showed that there were statistically significant differences at a significance level of p<0.05 between the second and third group. As for the first and second group, there was a slight increase, but not significant, p>0.05. The results of the study also showed that there was a significant difference (p<0.01) between the first group and the third group. As for the level of interleukin 8, there was a significant difference at the significance level of p<0.05 between the three groups.
A comprehensive review on pharmacological, phytochemical and anticancer potential of Tragia species
Authors: Ranjusha V.P. , Ranjithkumar D. , Sangilimuthu Alagar Yadav
Published: August 2024

Genus Tragia is a member of Euphorbiaceae family and is frequently found in tropical environments. There are more than 150 species in Tragia. Tragia plant is widely distributed in India and East Africa peninsula. Tragia has been designated for multiple medicinal properties including anti-bacterial, anti-inflammatory, anti-fungal, reproductive, diarrhoea, scorpion bite, whooping cough, diabetes etc. These are few medicinal benefits of Tragia. Tragia is also used in ethno medical research. Tragia involucrata, Tragia spathulata, Tragia benthamii, Tragia pluknetii, Tragia urens, Tragia nepetifolia and Tragia urticifolia are the principal species being researched worldwide. By the conventional wisdom, Tragia would be a component in siddha and ayurvedic medicine. Pharmacologically, many phytochemicals including lignans, alkaloids, flavonoids, terpenoids and phenolic substances, have been linked to these characteristics. The combined effects of these phytoconstituents greatly enhance their potential as medicinal agents. Moreover, this review discusses the challenges and future prospects in harnessing the full therapeutic potential of Tragia species. Issues such as standardization of extracts, elucidation of specific active compounds and clinical translation are addressed, highlighting areas that require further research.
Hubungan Beban Kerja dengan Kelelahan Kerja pada Perawat Instalasi Rawat Inap di Rumah Sakit Islam Malahayati Medan
Authors: Sumantri Sakina , Utami Tri Niswati , Astuty Delfriana Ayu
Published: August 2024

Beban kerja merupakan sesuatu yang muncul dari interaksi antara tuntutan tugas, lingkungan kerja, keterampilan, perilaku dan persepsi dari pekerja. Beban kerja merupakan salah satu faktor yang dapat mengakibatkan kelelahan. Kelelahan kerja perawat merupakan gejala yang berhubungan dengan penurunan efesiensi kerja, keterampilan, serta kebosanan pada perawat. Tujuan: penelitian Tujuan penelitian adalah untuk mengetahui hubungan antara beban kerja dengan kelelahan kerja pada perawat pelaksana di Instalasi Rawat Inap rumah sakit islam malahayati medan. Metode: Penelitian ini merupakan jenis penelitian kuantitatif. Desain penelitian observasional analitik dengan pendekatan cross sectional dengan 71 Responden, Populasi pada penelitian ini adalah seluruh perawat di instalasi rawat inap rumah sakit islam malahayati medan. Cara pengambilan sampel menggunakan total sampling. Instrumen yang dipergunakan adalah kuesioner beban kerja dari nursalam dengan 13 pertanyaan dan kuesioner kelelahan kerja dari alat ukur perasaan kelelahan kerja denagan 17 pertanyaan. Kedua variable tersebut dianalisis dengan menggunakan uji Chi Square. Hasil: beban kerja yang berat yaitu sebanyak 47 orang (66%). Sebagian besar responden mengalami kelelahan kerja tinggi dengan kategori lelah yaitu sebanyak 41 orang (58%). Pembahasan: Dari hasil penelitian yang didapatkan adanya hubungan secara signifikan beban kerja dengan kelelahan kerja pada perawat (p-value=0,017). Beban kerja perawat yang tinggi akan menyebabkan kelelahan kerja perawat. Kelelahan kerja akan berdampak pada pelayanan kepada pasien tidak optimal sehingga berisiko terhadap keselamatan pasien. Hasil penelitian dapat menjadi tolak ukur serta pertimbangan untuk dikembangkannya materi pembelajaran tentang beban kerja terhadap kelelahan kerja beserta faktor-faktor lainnya yang akan memengaruhi beban kerja perawat.
Micellar effects of dicationic surfactants in base catalyzed hydrolysis of acyl substrates. Surfactant and substrate structure role. Review
Authors: Прокопьева Т.М. , Белоусова И.А. , Гайдаш Т.С. , Разумова Н.Г. , Котенко А.А. , Михайлов В.А.
Published: August 2024

Установление природы влияния организованных микрогетерогенных систем (ОМС) на реакционную способность гидроксид-иона в процессах щелочного гидролиза ацилсодержащих субстратов в рамках подхода «структура ПАВ / субстрата – свойство – мицеллярные эффекты» – основа создания высокоэффективных нуклеофильных систем для разложения экотоксикантов, в том числе, фосфорорганических соединений. Кинетические закономерности щелочного гидролиза в микрогетерогенных системах на базе димерных катионных, функционализированных ПАВ и их мономерных аналогов проанализированы с использованием псевдофазной распределительной модели. Максимальный каталитический эффект при переносе процесса из воды в мицеллы детергентов достигает от 10 до 100 раз. Увеличение скорости реакции связано не только с концентрированием реагентов в мицеллярной псевдофазе, но и с изменением нуклеофильности гидроксид-иона, обусловленного характером микроокружения. Мицеллярные эффекты ПАВ зависят от гидрофобности субстрата и детергента (длины алкильного «хвоста», природы полярной группы и мостикового звена). Введение гидроксильной группы в мостиковое звено создает дополнительные возможности для межмолекулярных взаимодействий и обеспечивает рост наблюдаемых скоростей реакции по сравнению с мономерными детергентами и димерными ПАВ с метиленовыми мостиковыми фрагментами.

The basis for creation of effective nucleophilic systems for ecotoxicants destruction including phosphororganic compounds lies in the revelation of principles of microheterogeneous systems organization and their influence on hydroxide ion reactivity in the hydrolysis of acyl-containing substrates, in a frame of “surfactant/substrate structures – properties – micellar effects”. Kinetics of base catalyzed hydrolysis in organized microheterogeneous systems based on functionalized dicationic surfactants and their monocationic analogs were analyzed with pseudophase distribution model. Transfer from water into surfactant micelles leads to reaction rate enhancement up to 100-fold. This rate enhancement coupled with not only reagents concentration in micelle pseudophase but with changes in nucleophilicity of hydroxide-ion caused by environment. Surfactant micellar effects depend on hydrophobicity of substrate and surfactant (alkyl tale length, polar group and spacer nature). Hydroxyl group introduction into intercationic linkage creates additional opportunities for intermolecular interactions and provides micellar effects growths compared with monocationic surfactants, and dicationic surfactants with aliphatic spacers.
Comparative assessment of the composition and properties of rhodium compounds with supramolecules
Authors: Гусева Е.В. , Фесик Е.В.
Published: August 2024

Представлены результаты исследований по сравнительной оценке влияния супрамолекул ‒ каликс[4]резорцинов и дибензо-18-краун-6, функционализированных различными фрагментами (гидроксиэтокси-, фосфорил-, амино-, нитрогруппами) на состав продуктов, которые образуются при их взаимодействии с акватрихлоридом родия (III) и диакватетраацетатом диродия (II) в органических средах. Установлено, что выделение и состав продуктов определяется свойствами органической среды. Показана взаимосвязь между исследованными функциональными свойствами комплексных соединений, такими как каталитическая, бактерицидная и антиоксидантная активность, и их составом и строением. Исследованные закономерности влияния растворителей на выделение термодинамически стабильных продуктов в твердую фазу в виде супрамолекулярных комплексов родия разнообразного состава и строения открывает широкие перспективы для управления процессами минимизации потерь родия в отходах химической промышленности, связанной с соединениями, участвующими в катализе и проводимых в неводных органических средах. Ключевые слова: родий, супрамолекулы, функционализированные каликс[4]резорцины, функционализированные дибензо-18-краун-6 эфиры, влияние растворителей, состав продуктов, взаимосвязь функциональных свойств и состава.

The results of studies on the comparative assessment of the effect of supramolecules ‒ calix[4]resorcins and dibenzo-18-crown-6 functionalized by various fragments (hydroxyethoxy-, phosphoryl-, amino-, and nitro groups) on the composition of products formed by their interaction with rhodium (III) aquatrichloride and diaquatetraacetate of dirodium (II) in organic environments. It has been established that the isolation and composition of products is determined by the properties of the organic medium. The relationship between the studied functional properties of complex compounds, such as catalytic, bactericidal and antioxidant activity, and their composition and structure is shown. The studied patterns of the influence of solvents on the release of thermodynamically stable products into the solid phase in the form of supramolecular rhodium complexes of various compositions and structures opens up broad prospects for controlling the processes of minimizing losses of rhodium in chemical industry waste associated with compounds involved in catalysis and carried out in non-aqueous organic media. Keywords: rhodium, supramolecules, functionalized calix[4]resorcins, functionalized dibenzo-18-crown-6 esters, the effect of solvents, the composition of the products, the relationship of functional properties and composition.
Emissions of hydrogen fluoride into the atmosphere and its toxicological effect on natural objects ‒ a review
Authors: Громов О.Б. , Корниенко М.Ю. , Травин С.О. , Ахтямова М.Л. , Михеев П.И.
Published: August 2024

В статье рассмотрены возможные источники выбросов фтороводорода в окружающую среду. Проанализированы механизмы токсического действия HF на живые организмы. Проведено рассмотрение нормативных документов по ограничению таких выбросов. Выявлена несогласованность нормативов по классу опасности фтороводорода, что приводит к нарушению условий труда персонала производств. Показано, что фтороводород является особо опасным токсикантом (универсальным ферментным ядом) в окружающей среде. Обосновано, что фтороводород следует относить к веществам первого класса опасности.

The article considers possible sources of hydrogen fluoride emissions into the environment. The mechanisms of toxic effect of HF on living organisms were analyzed. Regulatory documents to limit such emissions were reviewed. Inconsistency of norms on the class of hydrogen fluoride hazard has been revealed, which leads to violation of labour conditions of the production personnel. It has been shown that hydrogen fluoride is a particularly dangerous toxicant (universal enzyme poison) in the environment. It is justified that hydrogen fluoride should be classified as a substance of the first hazard class.
Modernization of Pneumatic Systems and their Integration into the Process Control System of the Enterprise
Authors: Андриянов И.Н.
Published: August 2024

В статье затрагиваются вопросы замены существующих пневматических систем c их последующей интеграцией в АСУ ТП предприятия. Как пример рассматриваются пневматические контроллеры БАЗИС-ПВ производства АО «Экоресурс» (г. Воронеж).

The article touches upon the issues of replacing existing pneumatic systems with their subsequent integration into the plant’s automated process control system. As an example, we consider pneumatic controllers BAZIS-PV manufactured by JSC «Ekoresurs» (Voronezh).
Machine Learning as a Novel Approach to Process Automation and Production Cost Reduction in Oil and Gas Industry
Authors: Байбаров Д.А.
Published: August 2024

Предложена технология автоматизации технологических процессов с применением современных методов машинного обучения для разведки местонахождения новых скважин, повышения нефтеотдачи и уменьшения расходов на добычу, а также для прогнозирования добычи нефти на месторождении. В качестве параметров оптимизации рассматривается удельная механическая энергия для количественной оценки эффективности бурения и механическая скорость бурения. Представлены методы прогнозирования и оптимизации производительности бурения на основе технологий удельной механической энергии с учетом оценки достоинств и недостатков. Приведен сравнительный анализ прогнозирования скорости бурения двух существующих моделей машинного обучения с фактическими данными.

This study proposes automating technological processes using modern machine learning methods to explore the location of new wells, increase oil recovery, reduce production costs, and improve forecasting oil production in the field. As optimization parameters, specific mechanical energy to quantify drilling efficiency and mechanical drilling rate were taken. The paper presents methods for predict ing and optimizing drilling performance based on specific mechanical energy technologies and with account taken of the advantages and disadvantages’ evaluation. Apart from this, it provides a comparative analysis of the drilling rate prediction under two existing machine learning models with actual data given.
CONDITION AND PROSPECTS OF MODEL ASSESSMENT OF SURVIVAL OF THE SYSTEM «CLIMATE–BIOSPHERE–SOCIETY»
Authors: Варотсос К.А. , Крапивин В.Ф. , Мкртчян Ф.А.
Published: August 2024

На основе совершенствования информационных технологий предложен конструктивный подход для моделирования глобальных процессов в системе «климат–биосфера–общество», позволяющий адаптивно согласовать параметрическое и функциональное пространство глобальной модели. Представлена блок-схема глобальной модели системы климат–биосфера–общество и охарактеризованы функциональные возможности ее блоков. Структура модели представляет собой серию блоков, параметризующих глобальные биогеохимические циклы, гидрологический цикл, демографические процессы и простую модель климата. Показатель выживаемости используется как критерий живучести человечества. Он отражает динамику общей биомассы биосферы с учетом тенденций в динамике биологической сложности экосистем суши и гидросферы. Прогнозные возможности глобальной модели демонстрируются на конкретных примерах антропогенных сценариев. Рассматривается классификация наземной экосистемы с выделением 30 типов почвенно-растительных формаций для географических пикселей 4o×5o. Человечество представлено тремя традиционными группами экономического развития. Мировой океан представлен тремя широтными зонами. Результаты моделирования показывают динамику системы «климат–биосфера–общество» до начала 23-го столетия: численность населения мира может достичь уровня 14 млрд без возникновения заметных негативных процессов.

A constructive approach is proposed for the global modeling of processes in the «climate–nature–society» system based on the information technology that allows the adaptive agreement of parametrical and functional space of global model. Blockdiagram is represented for global model of the «climate–nature–society» system and func-tional capabilities of its blocks are characterized. A model structure represents a series of items describing global biogeochemical cycles, hydrological cycle, demographic processes, and simple climate model. Survivability indicator is used as a criterion of the humanity survivability. It defi nes a trend in the dynamics of total biosphere biomass taking into account the tendencies in biocomplexity dynamics of the land and hydrosphere ecosystems. Global model capabilities are demonstrated by means of concrete examples. A classifi cation of the land ecosystem is considered with the separation of 30 types of soil-plant formations for the geographical pixels 4o×5o. Humanity is represented by three traditional groups of economical development. The World Ocean is parameterized by three latitudinal zones. Modeling results show the dynamics of the «climate–nature–society» system to the beginning of the 23st century: world population can reach the level of 14 billions without the occurrence of grand negative processes.
AUTOMATED CALS-SYSTEM OF GEOECOLOGICAL MONITORING OF ANTI-ICING REAGENTS
Authors: Бессарабов А.М. , Приоров Г.Г. , Глушко А.Н.
Published: August 2024

Применение противогололедных реагентов для зимнего содержания дорог всегда сопровождается неизбежными экологическими последствиями, связанными с попаданием в окружающую среду большого количества химических веществ. Для снижения негативных последствий проводится экологический мониторинг состояния объектов окружающей среды, который позволяет оценить воздействие применяемых противогололедных реагентов по четырем важнейшим экологическим кластерам: почвенный покров, водные объекты, зеленые насаждения и атмосферный воздух. Экологический мониторинг осуществлялся с помощью систем компьютерного менеджмента качества, разработанных на основе информационных CALS-технологий. Разработана система геоэкологического мониторинга по результатам экспериментальных исследований сотрудников МГУ им. М.В. Ломоносова. Для исследований отбирались образцы с остатками реагентов с основных дорог города Москвы. Все анализы выполнялись с использованием новейшего аналитического оборудования.

The use of deicing agents for winter road maintenance is always accompanied by inevitable environmental consequences associated with the release of large amounts of chemicals into the environment. To reduce the negative consequences, environmental monitoring of the state of environmental objects is carried out, which makes it possible to assess the impact of the used anti-icing reagents for the 4 most important environmental clusters: soil cover, water bodies, green spaces and atmospheric air. Environmental monitoring was carried out using computer quality management systems developed on the basis of information CALS-technologies. A system of geoecological monitoring has been developed based on the results of experimental studies by employees of the of the Lomonosov University. For research, samples were taken with residues of reagents from the main roads of the city of Moscow. All analyzes were performed using the latest analytical equipment.
SYMBOLISM AND THE CONCEPT OF THE IMMERSIVENESS OF THE CIRCASSIAN (ADYGHE) MUSICAL PICTURE OF THE WORLD
Authors: Гучева А.В.
Published: August 2024

Рассмотрены основные концепции теории иммерсивности в исследовании музыкальной картины мира черкесов (адыгов) включающую музыку и музыкальный инструмент как элементов мифа и средоточие почти бесконечного количества аспектов мировосприятия, движимых многообразием конфликтующих и взаимодействующих единиц, выражающихся через знак, образ, символов, звук и т.д., которые являются одними из важных аспектов универсального целого, равно как и целое, распадающееся на множество структур и систем. В каждой единице целое воспринимается единым, но, по сути, не может быть отделено как часть, вмещающая всю множественность неограниченной и неисчислимой целостностью мифа. Подобный подход исследования обусловлен потребностью установления, кажущихся несвязанных единиц в порядок, с их взаимосвязями и открытыми законами миро-восприятия и мифо-восприятия музыки/наигрыша музыкальной картины мира с таким важным символом мифологической картин мира как «вода». В данной статье рассматриваются расширение и углубление влияния мистицизма звучания в сочетании с архаическим колоритом медитации посредством камыля в контексте религиозных обрядов черкесов (адыгов) через их реконструкцию/ретроспекцию. Определяются истоки и смысловая коннотация символов мифа и звучания адыгской свирели в трансцендентном состоянии для общения с божествами, а также проводится анализ малоизученных религиозно-мистических уровней в контексте музыкальной и мифической картин мира.

The main concepts of the theory of immersiveness in the study of the musical worldview of the Circassians (Adygs) are considered, including music and a musical instrument as elements of myth and the focus of an almost infi nite number of aspects of world perception, driven by a variety of conflicting and interacting units, expressed through a sign, image, symbols, sound and etc., which are one of the important aspects of the universal whole, as well as the whole, which splits into many structures and systems. In each unit, the whole is perceived as one, but, in fact, it cannot be separated as a part that contains all the multiplicity by the unlimited and innumerable integrity of the myth. This approach of research is due to the need to establish seemingly unrelated units in order, with their interrelations and open laws of worldperception and myth-perception of music/playing a musical picture of the world with such an important symbol of the mythological picture of the world as «water». This article discusses the expansion and deepening of the influence of the mysticism of sound in combination with the archaic flavor of meditation through kamyl in the context of the religious rites of the Circassians (Adygs) through their reconstruction/retrospection. The sources and semantic connotation of the symbols of the myth and the sound of the Adyghe pipe in a transcendent state for communication with deities are determined and the analysis of poorly studied religious and mystical levels in the context of musical and mythical pictures of the world is also carried out.
ELECTRIC LIGHTING OF THE IMPERIAL MIKHAILOVSKY THEATER
Authors: Петрущенков В.А.
Published: August 2024

Цель статьи – изучение истории создания систем электрического освещения, отопления и вентиляции в Императорском Михайловском театре. Процесс строительства электростанции Михайловского театра производился в несколько этапов в период с 1886 г. по 1896 г. В 1910 г. именно на электростанции Михайловского театра впервые в истории России Н.П. Мельников применил насосную циркуляцию водяного теплоносителя в системе отопления и вентиляции театра в условиях когенерации. Подробно рассмотрены организационные и технические особенности процесса создания и эксплуатации электростанции за весь период ее существования.

The purpose of the article is to study the history of the creation of electric lighting, heating and ventilation systems in the Imperial Mikhailovsky theater. The construction of the Mikhailovsky theater power plant was carried out in several stages between 1886 and 1896. In 1910, it was at the Mikhailovsky theater power plant that N.P. Melnikov applied pumping circulation of water coolant in the theater’s heating and ventilation system under cogeneration conditions for the first time in the history of Russia. The organizational and technical aspects of the process of creating and operating a power plant over the entire period of its existence are considered in detail.
Transmutations of the Genre of Instrumental Theater, or Artvision Music by Alexander Bakshi
Authors: Егорова Т.К.
Published: August 2024

В статье впервые предпринята попытка введения и научного обоснования термина АртВижн Музик (ArtVision Music). Основание тому дают некоторые из сочинений Александра Бакши, стоящие особняком в творчестве композитора, хотя мы вполне допускам, что подобного рода примеры в современном музыкальном искусстве не единичны. Причины для возникновения новой жанровой формы следует искать, с одной стороны, в непрекращающихся в течение нескольких десятилетий экспериментах в области инструментального театра, с другой – в качественных изменениях во всех формах (в том числе художественно-творческих) человеческой жизнедеятельности под воздействием начавшейся с середины 1980-х годов и продолжающейся по сей день цифровой революции (Digital Revolution), формировании новой (интерактивной) ментальности, что не может не оказывать влияния на способы существования, язык и систему выразительных средств современного музыкального искусства.

The article is the fi rst attempt to introduce and scientifically substantiate the term Artvision Music. The reason for this is given by some of the works of Alexander Bakshi, which stand alone in the composer’s work, although we fully admit that such examples are not isolated in modern musical art. The reasons for the emergence of a new genre form should be sought, on the one hand, in the ongoing experiments in the field of instrumental theater for several decades, on the other - in the qualitative changes in all forms (including artistic and creative) of human life under the influence of the digital revolution that began in the mid-1980s and continues to this day and the formation of a new (interactive) mentality, which cannot but affect the ways of existence, language and system of expressive means of modern musical art.
ESTIMATE OF ASYMPTOTICS OF THE MOMENTS OF ARITHMETIC FUNCTIONS HAVING A LIMITING DISTRIBUTION
Authors: ВОЛЬФСОН В.Л.
Published: August 2024

В последнее время, с развитием компьютерной техники и Интернета, проблема распределения простых чисел приобрела важное практическое значение, поскольку она напрямую связана с надежностью, так называемых крипто-графических систем с открытым ключом. Например, криптографическая стойкость широко применяемой в настоящее время системы шифрования RSA основана на вычислительной сложности разложения на простые множители больших натуральных чисел. В данной работе рассматривается метод оценки асимптотик арифметических функций в натуральном ряде. Данный вопрос тесно связан с распределением простых чисел в натуральном ряде. Даже с определением асимптотики среднего значения арифметических функций часто возникают проблемы, а тем более при определении асимптотик моментов, более высоких порядков. Поэтому в работе предлагается, отличный от традиционного, вероятностный подход, основанный на предельном распределении арифметических функций. В данной работе будет рассмотрен общий случай метода оценки асимптотик моментов аддитивных арифметических функций, имеющих предельное распределение. Доказаны несколько утверждений об оценке асимптотик моментов сильно аддитивных арифметических функций, а также аддитивных функций класса H, имеющих предельное распределение.

Recently, with the development of computer technology and the Internet, the problem of the distribution of prime numbers has acquired great practical importance, since it is directly related to the reliability of the so-called public key cryptographic systems. For example, the cryptographic strength of the currently widely used RSA encryption system is based on the computational complexity of factoring large natural numbers into prime factors. We consider a method for estimating asymptotics of arithmetic functions in the natural series in this paper. This question is closely related to the distribution of prime numbers in natural numbers. Even problems often arise with the definition of asymptotics of the mean value of arithmetic functions, and even more so in the determination of asymptotics of the moments of higher orders. Therefore, the paper proposes a different from the traditional, probabilistic approach based on the limiting distribution of arithmetic functions. We will consider the general case of a method for estimating asymptotics of the moments of additive arithmetic functions having a limit distribution in the paper. Several assertions are proved about the estimation of asymptotics of the moments of strongly additive arithmetic functions, as well as additive functions of the class H having a limit distribution.
Statistical Synthesis and Research of Decision-Making Algorithms in Redundant Measurement Systems With Failures
Authors: УФАЕВ В.А. , ВОЛОБУЕВ М.Ф.
Published: August 2024

В статье проведена оценка способов повышения надежности резервированных из-мерительных систем. Для этого уточнены и дополнены известные решения. С применением обобщённого метода максимального правдоподобия синтезированы алгоритмы обнаружения отказов и оценки информационного параметра. Для статистического описания измерений отказавших каналов резервированных измерительных систем предложены модели смещения и хаоса. Моделированием определены зависимости вероятностей принятия решений о числе отказов и средней квадратичной ошибки оценки информационного параметра от среднего квадратического отклонения математических ожиданий неисправных каналов, исследовано влияние видов законов распределения математических ожиданий на эффективность принятия решений.

The article evaluates the ways to improve the reliability of redundant measurement systems. For this purpose, the known solutions have been refined and supplemented. Using the generalized maximum likelihood method, algorithms for detecting failures and estimating the information parameter are synthesized. Models of offset and chaos are proposed for statistical description of measurements of failed channels of redundant measurement systems. The dependences of the decision-making probabilities on the number of failures and the mean square error of the information parameter estimation on the mean square deviation of the mathematical expectations of faulty channels are determined by modeling, and the influence of the types of mathematical expectation distribution laws on the decision-making efficiency is studied.
Investigation of Phase Fluctuations of the Output Signal of the Phase Measurement System
Authors: МАЙОРОВ Е.Е. , КОЛЕСНИЧЕНКО С.В. , КОНСТАНТИНОВА А.А. , МАШЕК А.Ч. , ПИСАРЕВА Е.А. , ЦЫГАНКОВА Г.А.
Published: August 2024

В представленной работе приведено исследование флуктуаций фазы выходного сигнала системы фазовых измерений. Получение высокоточной и достоверной информации о контролируемых предметах разной формы всегда являлось важной задачей оптического приборостроения, поэтому работа актуальна. В работе исследуется случайная модуляции фазы выходного сигнала при извлечении данных с интерферограммы, которая дает возможность оценить влияние спекл-поля на погрешность измерений и диапазон вариации высоты рельефа контролируемой формы предмета. Получены флуктуации фазы выходного сигнала при апертуре воспроизводящего волнового фронта с разным диаметром. Экспериментально определены величины среднеквадратичного отклонения фазы выходного сигнала от среднего значения при движении интерферограммы при разном диаметре.

The paper a study of the phase fluctuations of the output signal of the phase measurement system is presented. Obtaining high-precision and reliable information about controlled objects of various shapes has always been an important task of optical instrumentation, so the work is relevant. The paper investigates the random phase modulation of the output signal when extracting data from an interferogram, which makes it possible to assess the effect of the speckle field on the measurement error and the range of variation in the height of the relief of the controlled shape of the object. Fluctuations in the phase of the output signal at the aperture of the reproducing wavefront with different diameters are obtained. The values of the standard deviation of the output signal phase from the average value when the interferogram moves at different diameters are determined experimentally.
Information Resources for the Realization of Desicion Support Systems
Authors: БАКАНОВ А.С.
Published: August 2024

Корпоративные информационные системы предназначены для передачи, хранения и предоставления информации, необходимой для деятельности организации. В свою очередь, принятие управленческих решений является основным содержанием деятельности организации. В современных организациях, управленческое решение принимается в электронном виде, передается по информационным каналам организации. В основе управленческого решения лежит информация, содержащаяся как в корпоративных, так и во внешних информационных ресурсах, т.е. по сути деятельность по принятию решения является деятельностью по обработке и передаче информации. Каждой организации присущи специфические особенности процессов обработки информации, и они находят свое отражение в процессах принятия решений. Специфические особенности в управленческой деятельности отражаются: в структуре организации; в ведомственных нормативах и регламентах; в организационных технологиях выполнения работ. Вся вышеперечисленная информация может быть использована в системах поддержки принятия решений для анализа принятых решений на основе прецедентов.

Corporate information systems are designed to transfer, store and provide information necessary for the activities of an organization. In turn, making management decisions is the main content of the organization’s activities. In modern organizations, a management decision is made in electronic form, transmitted through the organization’s information channels, the management decision is based on information contained in both corporate and external information resources, i.e. in essence, decision-making activities are information processing and transmission activities. Each organization has specific features of information processing processes, and they are reflected in decision-making processes. Specific features in management activities are reflected: in the structure of the organization; in departmental standards and regulations; in organizational technologies for performing work. All of the above information can be used in decision support systems to analyze decisions made based on precedents.
The Catalytic Mechanism of the Plastic-Degrading Enzyme Urethanase UMG-SP2
Authors: Paiva Pedro , Teixeira Luís M. C. , Wei Ren , Liu Weidong , Morth Jens P. , Westh Peter , Petersen Allan R. , Johansen Martin B. , Sommerfeldt Andreas , Sandahl Alexander , Otzen Daniel E. , Fernandes Pedro A. , Ramos Maria J.
Published: August 2024

The recently discovered metagenomic urethanases UMG-SP1, UMG-SP2, and UMG-SP3 have emerged as promising tools to improve existing chemical processes for polyurethane (PU) waste recycling. These enzymes are capable of breaking down urethane bonds in low molecular weight dicarbamates using the Ser-Sercis-Lys triad for catalysis, similar to other members of the amidase signature protein superfamily. Understanding the catalytic mechanism of these urethanases is crucial for enhancing their enzymatic activity and improving PU bio-recycling processes. In this study, we employed hybrid quantum mechanics/molecular mechanics methods to delve into the catalytic machinery of the UMG-SP2 urethanase in breaking down a model PU substrate. Our results indicate that the reaction proceeds in two stages: STAGE 1 acylation, in which the enzyme becomes covalently bound to the PU substrate, releasing an alcohol-leaving group; STAGE 2 - deacylation, in which a catalytic water hydrolyzes the enzyme:ligand covalent adduct, releasing the product in the form of a highly unstable carbamic acid, expected to rapidly decompose into an amine and carbon dioxide. We found that STAGE 1 comprises the rate-limiting step of the overall reaction, consisting of the cleavage of the substrate’s urethane bond by its ester moiety and the release of the alcohol-leaving group (overall Gibbs activation energy of 20.8 kcal·mol-1). Lastly, we identified point mutations that are expected to enhance the enzyme's turnover for the hydrolysis of urethane bonds by stabilizing the macrodipole of the rate-limiting transition state. These findings expand our current knowledge of urethanases and homolog enzymes from the amidase signature superfamily, paving the way for future research on the enzymatic depolymerization of PU plastic materials.
Desenvolvimento e implementação de um sistema de triagem para cães e gatos em um hospital veterinário
Authors: Fonseca Ana Claudia da , Braga Larissa Reis , Sousa Felipe Gaia de , Melo Eliane Gonçalves de , Beier Suzane Lilian
Published: August 2024

Sistemas de triagem para reconhecimento e classificação da gravidade dos quadros clínicos ainda não estão disponíveis para a área veterinária, de forma que os animais muitas vezes são atendidos de forma distinta, como por ordem de chegada ou por agendamento prévio. Diante da ausência de um sistema de triagem validado e reconhecido para reconhecimento e classificação dos atendimentos para cães e gatos, objetivou-se adaptar o Sistema de Triagem de Manchester (STM) para um hospital veterinário e avaliar seus benefícios quando da sua implementação. Participaram do estudo cerca de 553 animais e seus responsáveis e/ou tutores legais, sendo 275 na primeira fase e 278 na segunda fase. A espécie canina foi predominante no estudo (84,8%; n=469/553) e a idade média dos animais foi de 81,33 meses. O nível de prioridade mais selecionado foi o verde, seguido da categoria azul, amarelo, vermelho e laranja em ambas as fases. A superioridade do novo sistema de ordenação foi notória quando comparado ao sistema de ordenação intuitivo. O sistema de triagem desenvolvido e modificado proporcionou maior número de pacientes triados, melhor aceitação por parte dos tutores e/ou responsáveis legais e demonstrou maior clareza quanto ao estado de gravidade dos pacientes. Mais estudos são necessários para avaliar a eficiência e a eficácia dos sistemas de triagem na rotina veterinária, porém sua superioridade ao sistema de triagem intuitivo foi evidente.
ANTIBODIES AGAINST Leptospira spp. IN DAIRY CATTLE IN A FAMILY AGRICULTURE SYSTEM
Authors: Curci Vera Cláudia Magalhães , Magajevski Fernanda Senter , Moreli Fernando Christiano Gabriel , Romaldini Adriana Hellmeister de Campos Nogueira , Costa Ricardo Lopes Dias da , Oliveira Talita Carolina Bragança de , Cardoso Tereza Cristina , Manzini Suzane , Cavalheiro Maria Eduarda , Alexandrino Marcela , Bertozzo Thainá Valente , Steinle Jackieline Sampaio , Gomes Andresa Xavier Frade , Aires Isabella Neves , Lucheis Simone Baldini , Girio Raul José Silva
Published: August 2024

Leptospirosis is an endemic zoonosis in Brazil responsible for numerous reproductive and economic losses to the dairy industry. Brazil ranks fifth in the world's production of cow's milk and around 23 million cows are milked every day. The northwest region of the state of São Paulo has a considerable number of family farming settlements, with dairy farming being predominant. This article reports a seroepidemiological study to detect agglutinins against Leptospira spp. in 1,004 dairy cattle kept on 64 family farms producing milk in the northwest region of São Paulo. Management and environmental data for situation diagnosis were obtained with a questionnaire. Antibodies against Leptospira spp. were investigated by the microscopic seroagglutination test (SAM) and milk and urine samples were obtained from seroreactive animals with titer ? 400. These samples were submitted to molecular tests. Of the 64 properties studied, 63 (98%) had seroreactive animals. Of the 1,004 animals, 523 (52%) were reactive. According to the molecular tests, the presence of Leptospira spp. in the urine and milk of the seroreactive animals was negative. Wetlands, presence of rodents, occurrence of abortion, presence of dogs, presence of cats and presence of horses were variables associated with the risk of infection by Leptospira spp. In addition to its importance in animal health, leptospirosis poses a risk to human health, a situation that indicates the need for improvement of sanitary conditions in rural properties.
Removal of power line interference from ECG signal
Authors: Monika Mishra , Awadhesh Kumar , Giri V. K.
Published: August 2024

Electrocardiogram (ECG) signals are vital for diagnosing cardiac abnormalities, but they are corrupted by powerline interference noise, which can obscure critical features and compromise diagnostic accuracy. This paper investigates various filtration techniques aimed at effectively removing powerline interference noise from ECG signals. Different approaches, including average filters and moving average filters, are explored and compared to determine their efficacy in noise reduction while preserving important signal characteristics. Experimental evaluations are conducted using synthetic ECG signals contaminated with simulated powerline interference noise and real-world ECG recordings corrupted by actual powerline interference. The performance of each filtration technique is assessed based on metrics such as Root Mean Square Error (RMSE) and Percentage Root Mean Square Difference (PRD). The trade-offs between noise reduction effectiveness and preservation of ECG signal fidelity are analyzed to identify the most suitable approach for clinical applications. This paper provides valuable insights into the selection and implementation of filtration techniques for mitigating powerline interference noise in ECG signals. The findings contribute to the development of robust signal processing methods for improving the reliability and accuracy of ECG-based diagnostic systems.
A novel communication system based on sign language recognition and voice conversion for differently abled person
Authors: Sandhiya J. A. L. , Pugalvani S. , Sowmiya S. S. , Vishalini C.
Published: August 2024

Sign language is a form of communication that helps deaf and mute people interact with those who can hear. In the country, around 2.78% of people are unable to speak, i.e., are mute or deaf. Their primary means of communication is through hand motions and gestures. The paper proposes a new technique called the "artificial speaking mouth" for individuals with speech impairments. Humans connect with each other through thoughts and ideas, but some people lack the ability to speak. For them, sign language is the only means of communication. Nowadays, technology has reduced this communication gap with systems that translate sign language into speech. Sign Language Recognition (SLR) and gesture-based control are two major applications used for hand gesture recognition technologies. On the other hand, the controller converts sign language into text and speech, using text-to-speech conversion and analog-to-digital conversion.