bluuebunny/crossref_metadata_2025 huggingface dataset:
MORPHOLOGICAL AND ANATOMICAL STRUCTURE OF PLANTSALLIUM TURKESTANICUM AND ALLIUM GALANTHUM
Authors: КАДЫРБАЕВА Г.М. , САКИПОВА З.Б. , ЖУМАШОВА Г.Т. , АЛЛАМБЕРГЕНОВА З. Б. , КУРМАНАЛИЕВА Ш.М.
Published: September 2022

В статье представлены результаты установления идентификационных параметров растительного сырья рода Allium лука туркестанского (Allium turkestanicum) и лука молочноцветного (Allium galanthum). Изучение макро- и анатомо-диагностических признаков проводили согласно общей фармакопейной статье ГФ РК. В результате проведенных исследований выявлены характерные диагностические признаки, которые позволяют достоверно идентифицировать лекарственное растительное сырье и могут быть использованы при разработке нормативной документации по разделам «Внешние признаки» и «Микроскопические признаки». Морфолого-анатомические признаки лука туркестанского (Allium turkestanicum) и лука молочноцветного (Allium galanthum изучены впервые.

The article presents the results of establishing the identification parameters of plant raw materials of the genus Allium of Allium turkestanicum and Allium galanthum. The study of macro- and anatomical diagnostic signs was carried out according to the general pharmacopoeia article of the SPh RK. As a result of the conducted studies, characteristic diagnostic signs have been identified that make it possible to reliably identify medicinal plant raw materials and can be used in the development of regulatory documentation for the sections "External signs" and "Microscopic signs". Morphological and anatomical features of Allium turkestanicum and Allium galanthum have been studied for the first time.
MATERIALS USED IN DENTAL IMPLANTATION. (LITERATURE REVIEW)
Authors: ТЛЕШЕВ М.Б. , АЛТЫНБЕКОВ К.Д. , НЫСАНОВА Б.Ж. , ШАЯХМЕТОВА М.К.
Published: September 2022

Статья посвящена одной из актуальных проблем современной стоматологии. Проведен анализ публикаций, посвященных особенностям материалов используемых при изготовлении дентальных имплантатов и требований к ним. Лечение пациентов с полным или частичным отсутствием зубов является одной из наиболее актуальных проблем современной стоматологии. В следствии утраты зубов происходит атрофия альвеолярного отростка что приводит к развитию неблагоприятных последствий для челюстнолицевой области и всего организма в целом. Обширные атрофические процессы костных тканей челюстей часто является факторами, препятствующими использованию традиционных методов протезирования. Использования дентальных имплантатов в ортопедической стоматологии позволило значительно повысить возможности протезирования. Протезирование зубов на имплантатах несет в себе задачу восстановление дефектов зубных рядов и создание опор там, где имеются затруднения для фиксации традиционных ортопедических конструкций.[1,2,3]

The article is devoted to one of the urgent problems of modern dentistry. The analysis of publications devoted to the characteristics of the materials used in the manufacture of dental implants and the requirements for them was carried out. Treatment of patients with complete or partial absence of teeth is one of the most urgent problems of modern dentistry. As a result of the loss of teeth, atrophy of the alveolar process occurs, which leads to the development of adverse consequences for the maxillofacial region and the whole organism as a whole. Extensive atrophic processes in the bone tissues of the jaws are often factors that prevent the use of traditional methods of prosthetics. The use of dental implants in orthopedic dentistry has significantly increased the possibilities of prosthetics. Dental prosthetics on implants has the task of restoring defects in the dentition and creating supports where there are difficulties for fixing traditional orthopedic structures.
POSSIBILITIES OF THE TEST OF SPEECH AUDIOMETRY IN THE KAZAKH LANGUAGE OF HEARING AID
Authors: СУАТБАЕВА Р.П. , ТАУКЕЛЕВА С.А. , ТОГУЗБАЕВА Д.Е. , МУКАНОВА Ж.Т. , НУКУСБЕКОВА Г.И.
Published: September 2022

Результаты опросников THI и TRQ показали, что использование программы фрактального тона снизило нагрузку на шум в ушах у 90% пациентов с 440 слуховыми аппаратами. Чем ниже возраст пациента, тем больше терапевтический эффект от использования программы. По мере увеличения количества баллов уменьшалась вероятность положительного эффекта фрактальных тонов.

The results of the THI and TRQ questionnaires showed that the use of the fractal tone program reduced the burden of tinnitus in 90% of patients with 440 hearing aids. The lower the age of the patient, the greater the therapeutic effect of using the program. As the number of points increased, the probability of a positive effect of fractal tones decreased.
BIRTH OUTCOMES AND PERINATAL LOSSES IN RH NEGATIVE BLOOD FACTOR IN MOTHERS
Authors: АЯЗБЕКОВ А.К. , НУРХАСИМОВА Р.Г. , КУРМАНОВА А.М. , САЛИМБАЕВА Д.Н. , АЯЗБЕКОВА А.Б. , ТЕРЛИКБАЕВА А.Т.
Published: September 2022

Проведен ретроспективный анализ 260 медицинских карт родильниц с резус-отрицатльным фактором и их новорожденных. Частота выявления резус-отрицательного фактора составила 2,6% от всей популяции родильниц. При наличии резус-сенсибилизации резко возрастает частота преждевременных родов (31,2%), госпитализаций новорожденных в палату интенсивной терапии (93,7%), новорожденные характеризуются низким весом и более низким баллом по шкале Апгар. У резус-отрицательных женщин с неизвестным статусом по резус-сенсибилизации наблюдались случаи гемолитической болезни новорожденных, мертворождения, необходимости в интенсивной терапии новорожденных. Это указывает на то, что частота резус-конфликта в общей популяции женщин с резус-отрицательным фактором крови выше, чем регистрируется. Разработка профилактической стратегии для данного контингента женщин является резервом улучшения качества оказания перинатальной помощи.

A retrospective analysis of 260 medical records of puerperas with Rh-negative factor and their newborns was carried out. The frequency of detection of the Rh-negative factor was 2.6% of the entire population of puerperas. In the presence of Rh sensitization, the frequency of preterm birth (31.2%), hospitalizations of newborns in the intensive care unit (93.7%) increases sharply, newborns are characterized by low weight and a lower Apgar score. In Rh-negative women with an unknown Rh-sensitization status, there have been cases of hemolytic disease of the newborn, stillbirth, and the need for neonatal intensive care. This indicates that the frequency of Rh conflict in the general population of women with Rh-negative blood factor is higher than recorded. The development of a preventive strategy for this contingent of women is a reserve for improving the quality of perinatal care.
ASSESSMENT OF DENTAL HEALTH AND CRITERIA FOR THE USE OF THE ICDAS INDEX IN CHILDREN AND ADOLESCENTS
Authors: Каркимбаева Г.А. , Рысбаева Ж.И. , Досбердиева Г.Т.
Published: September 2022

Анализ стоматологического здоровья детей Кызылординской области показал высокую распространенность стоматологической заболеваемости в сравнительном аспекте, что еще раз подтверждает влияние сложившейся критической экологической среды на растущий организм. Использование индекса IСDАS было эффективным инструментом для ранней и точной диагностики кариозных поражений, что позволило установить активные кариозные поражения в каждом зубе. Сравнительная характеристика актуальности кариозных поражений зубов у 6-8-летних школьников показало, что наиболее часто они располагаются на окклюзионных поверхностях (62,96%) и наиболее редко - на апроксимальных поверхностях (37,03%).

The analysis of the dental health of children in the Kyzylorda region showed a high prevalence of dental morbidity in a comparative aspect, which once again confirms the influence of the current critical environmental state on the growing organism. The use of the ICDAS index was an effective tool for early and accurate diagnosis of carious lesions, which made it possible to establish actual carious lesions in each tooth. The leveling character of the relevance of carious defeated teeth in 6-8-year-old schoolchildren showed that they are located on occlusal surfaces (62.96%) and more rarely on proximal surfaces (37.03%).
ASSESSMENT OF EARLY NEPHROTOXICITY IN TGC RECIPIENTS
Authors: МУРЗАХМЕТОВА А.О. , КЕМАЙКИН В.М. , АЙНАБАЙ А.М. , МЕЙРАМОВА А.М. , ВОРОБЬЕВ П.А. , АЙНАБЕКОВА Б.А.
Published: September 2022

На базе Национального научного онкологического центра Министерства Здравоохранения Республики Казахстан (г. Нур-Султан) были исследованы функции почек у 35 больных с острым миелобластным лейкозом в ранний период после трансплантации гемопоэтических стволовых клеток. Оценка функционального состояния почек до трансплантации гемопоэтических стволовых клеток и в ранний период после трансплантации не отразили статистически значимых изменений. Скорость клубочковой фильтрации у больных с острым миелобластным лейкозом до трансплантации гемопоэтических стволовых клеток составило в среднем 122 мл/мин/1,72м2 и была снижена до 116.2 мл/мин/1,72м2. Результаты нашего исследования показали, что больные с острым миелобластным лейкозом в ранний период после трансплантации гемопоэтических стволовых клеток имеют снижение скорости клубочковой фильтрации. При этом, у двоих больных с острым миелобластным лейкозом мы выявили снижение скорости клубочковой фильтрации до 60 мл/мин/1,72м2. Данные результаты не исключают вероятность токсичности терапии на функции почек, что требует дальнейших исследований у больных с острым миелобластным лейкозом перенесших трансплантацию гемопоэтических стволовых клеток.

Kidney functions in 35 patients with acute myeloblastic leukemia in the early period after hematopoietic stem cell transplantation were studied on the basis of the National Scientific Oncological Center of the Ministry of Health of the Republic of Kazakhstan (Nur-Sultan). Evaluation of the functional state of the kidneys before hematopoietic stem cell transplantation and in the early period after transplantation did not reflect statistically significant changes. The glomerular filtration rate in patients with acute myeloblastic leukemia before hematopoietic stem cell transplantation averaged 122 ml/min/1.72 m2 and was reduced to 116.2 ml/min/1.72 m2. The results of our study showed that patients with acute myeloblastic leukemia in the early period after hematopoietic stem cell transplantation have a decrease in glomerular filtration rate. At the same time, in two patients with acute myeloblastic leukemia, we detected a decrease in the glomerular filtration rate to 60 ml/min /1.72 m2. These results do not exclude the possibility of toxicity of therapy on kidney function, which requires further studies in patients with acute myeloblastic leukemia who underwent hematopoietic stem cell transplantation.
Ciclo de vida y curva de crecimiento de la cepa Simocephalus mixtus imarpe sp. nov. (IMP-BG Z021) (Cladocera: Daphniidae) en condición ex situ
Authors: Sanchéz-Dávila Pedro Pablo , Silva-Briano Marcelo , Adabache-Ortiz Araceli , Cavero-Arana José Gustavo , Polar-Pérez Mario Manuel
Published: September 2022

Se empezó un monocultivo a partir de una hembra partenogenética de la cepa Simocephalus mixtus imarpe sp. nov. IMP-BG-Z021 de la laguna Jitarayoc o Guitarra Yoc en la Región Ayacucho sobre 4600 msnm. Se evaluó el crecimiento diario de una muestra (n= 60) nacidos en un intervalo de 8 horas, el fitness fue alterado al medir los mismos individuos a lo largo de su vida, observándose un comportamiento resistente a la manipulación. Los individuos fueron criados en un beaker de medio litro dentro de una cámara climática a 16 °C, fotoperiodo 14:12 O: L, salinidad 0‰ y fueron alimentados con la microalga Chlorella sp. Se registraron los parámetros longevidad (75 días), progenie (20,4 crías/hembra en promedio), etapa pre reproductiva (8 días), reproductiva y post reproductiva casi ausente. Además, se consideraron los parámetros biométricos longitud y ancho durante el desarrollo de las crías (708,99 µm) hasta su adultez (2063,39 µm) y eclosión de huevos de resistencia o efipio al aumentar 8 °C dela temperatura en la que se desarrolló. La tasa de crecimiento individual fue k= 13,69 y su longitud máxima fue 2750 µm. Se propone la relación de procesos de especiación con las características geológicas del hábitat, así como la conservación de esta cepa como organismos andinos aptos para experimentación y alimento vivo nativo debido a su rusticidad al manejo y adaptación a temperaturas templadas.
Depredadores tope en la pesquería industrial de anchoveta entre los años 2015 y 2019
Authors: Rivadeneyra-Villafuerte Sofía , Román-Amancio Gersson
Published: September 2022

Las interacciones entre los depredadores tope y las pesquerías suponen una problemática global que tiene impacto sobre diversas poblaciones de especies de interés ecológico. El Programa Bitácoras de Pesca del Instituto del Mar del Perú aporta información sobre estas interacciones mediante la observación directa de los lances de pesca de las embarcaciones industriales de anchoveta. Entre los años 2015 y 2019 se realizaron 12.778 lances de pesca de anchoveta con presencia de depredadores tope, observándose mayor existencia de aves marinas que de mamíferos marinos, y se destaca el zarcillo Larosterna inca (26,69% del total de los lances), pelícano Pelecanus thagus (24,44%), piquero peruano Sula variegata (22,95%) y lobo chusco Otaria flavescens (36,69%). La distribución de aves y mamíferos marinos a lo largo de la costa peruana estuvo asociada a la plataforma continental y a la presencia de mayores colonias en la costa norte – centro. Es importante destacar que entre los años 2015 y 2016 se registró la menor cantidad de avistamientos de depredadores tope, lo que estaría relacionado con el evento El Niño ocurrido en esos años.
Técnicas de teledetección para identificar posibles áreas contaminadas por colectores residuales en el litoral peruano
Authors: Velaochaga Germán
Published: September 2022

Se recolectaron datos de reflectancia de las zonas de Piura, Áncash e Ica, desde el 7 de junio hasta el 22 de setiembre 2019. Se realizó un análisis de correlación de los datos recolectados con datos del satélite Sentinel-2, obteniéndose baja correlación debido a factores tales como la geometría de adquisición, la  diferencia temporal entre otros. Se realizó una clasificación supervisada a un mosaico compuesto por imágenes del satélite Sentinel-2 desde la zona de  Tumbes hasta Tacna para identificar posibles áreas contaminadas por colectores residuales, reconociendo un colector que se encuentra a 50 metros de profundidad y que genera una pluma de hasta 3 km en la superficie frente a Chorrillos y a 2 km de la costa.
Modelado de la circulación climatológica en la bahía de Pisco
Authors: Romero Carlos Yvan , Tam Jorge
Published: September 2022

La bahía de Pisco se encuentra en una zona en la cual el afloramiento se manifiesta persistentemente durante todo el año debido a la magnitud del viento cerca de sus costas, con mayor intensidad en invierno y primavera, lo cual hace posible la existencia de una amplia zona costera muy productiva y rica en nutrientes. Esta zona y sus islas adyacentes presentan gran diversidad de recursos pesqueros para el consumo humano directo, motivo por el cual tiene importancia para la pesquería artesanal del Perú. En este trabajo, se realizó el modelado de la bahía de Pisco utilizando el modelo oceánico regional ROMS y la herramienta ROMS2ROMS con el fin de conocer la circulación marina y la distribución espacial de las principales variables oceanográficas a pequeña escala en la bahía seleccionada. Para lograr esto, se utilizaron los resultados de una simulación del sistema de corrientes de Humboldt a escala regional (~12 km), como condiciones de frontera para realizar un downscaling dinámico utilizando la herramienta ROMS2ROMS para obtener la resolución espacial requerida (~ 1 km). El modelo reprodujo el ciclo estacional de la TSM en la bahía, con algunas diferencias en la intensidad de la TSM simulada y observada. Se encontró que la velocidad de las corrientes va en dirección noroeste con mayor intensidad al sur y al oeste de la península, alcanzando sus valores más altos en primavera (22,5 cm/s) y los más bajos en v erano (7,5 cm/s).
Learner Support Services in ODL: Gaps at Regional Level in Sindh, Pakistan
Authors: Arain Dr. Shahid Saleem , Munshi Parveen , Khan Sehrish
Published: September 2022

The current research studied the gaps in student support services at regional level in Pakistan. It was a mixed-methods case study research where explanatory sequential paradigm was used. The study was delimited to regional network of Allama Iqbal Open University Islamabad, in Sindh province. The sample of study comprised of 280 B.Ed. students and a focused group consisting of 14 students. The quantitative data was collected through self-developed five point Likert type questionnaire and qualitative data through semi-structured interview schedule. The descriptive and inferential statistics were used, findings were categorized according to themes, conclusions drawn and recommendations made. The finding of the study includes: poor academic and general facilities at study centers and regional centers. Lack of DE thought at regional centers, poor information system, useless communication through media, traditional and non-professional approach of ROs. The study recommends establishment of model study centers at tehsil level, use of ROs as model study centers and academic hubs, provision of physical facilities at study centers, arrangement of orientation programs, decentralization of books on regional level, attending DLs Add Contributorqueries through media, strong and meaningful two-way communication and appointment of DE qualified staff.
Impact of E-HRM and work from Home on Employee productivity during COVID-19: Evidence from Pharmaceutical companies
Authors: Subhan Prof. Dr. Abdul , Junejo Imran Khan , Kazi Abdul Ghafoor , Junejo Dr. Ikramuddin
Published: September 2022

The key objectives of this study to examine the impact of e-HRM and work from home on employee productivity during COVID-19 among pharmaceutical companies of Sindh, Pakistan. It is difficult for employee to perform at same level due to lockdown and pandemic situation in country. Total 250 employees are considered as sample size. In the present study there are 3 variables and each variable was consisting of 5 items. Due, COVID-19 questionnaire generated via google form and it shared via official e-mail of HR department of respective companies in order to complete the questionnaire. The random sampling techniques applied for in order to chance equal opportunity to be part of this research study. In order to test the proposed hypothesis questionnaire was taken from previous studies. Results revealed that the there is a significant and positive impact of e-HRM and work from home on employee productivity during COVID-19 in Pharmaceutical companies of Sindh, Pakistan. New insights of this study are in past research scholar verified the e-HRM with respect to employee productivity without context of COVID-19 situation and e-HRM and work from home are studied together. The policy makers and top management of Pharmaceutical companies of Sindh, Pakistan should consider these variables for better employee productivity during COVID-19.
Teachers’ Knowledge of ICT and e-learning in Pakistan: The wave of e-learning during COVID-19
Authors: Alam Aneela , Khurshid Farhana
Published: September 2022

World is experiencing major developments in its education system since the past two years due to COVID-19.  The e-learning came up as the only solution to sustain the education system during that period. But it questioned the teachers’ competence to deal with technology. Therefore, the need arouse to find out the teachers’ level of knowledge regarding integration of ICT into teaching and e-learning. Current study was planned to find out the teachers’ level of knowledge regarding ICT and e-learning. Sample of study were 251 secondary school teachers. They gave their response on the provided questionnaire. The study found that the teachers have advanced level of knowledge about the multiple technological tools and they also know about its usability. But the teachers are novice in the field of e-learning. The findings suggest that there is a need to first train the teachers so they may be able to utilize ICT for e-learning in classroom practices.
Education as Practice of Emancipation: A Critical Study of Educational Approach of Classical Pashto Poet Khushal Khan Khattak
Authors: Kakar Dr. Barkat Shah , Khan Abdul Wasai , Kakar Abdul Samad
Published: September 2022

Postmodern discourse on education, learning, and cognitive development of children and adolescents take us back to the fundamental questions of personality ethics, character ethics, skills and knowledge. Before the advent of European colonial system, most of the indigenous oriental communities had a vivid and tangible approach and philosophy of education, which is seldom heard and least discussed in the contemporary discourse. This research paper is going to unpack the educational paradigm of one of the most prominent poets, warrior, strategist, jurist, anthropologist, and nationalist leader known as Khushal Khan Khattak. The ideas, ideals and philosophy of Khushal Khan have been unearthed through various scholastic endeavors including 10 Ph.Ds in Pakistan, Afghanistan, Russia and other parts of the world. This paper takes on the glimpses from the poetry and prose of Khan especially with reference to his endeavors to nurture adolescents and children to cope up with challenges and opportunities. Khushal’s 20 traits/habits and 20 skills/arts narrated in his reckoned prose book “Dasthar-nama” are analyzed as core determinants of the ideological paradigms of his educational approach.
Botanical, chemical and pharmacological review of phaseolus vulgaris L. (common bean)
Authors: Bhide Yogesh Sharad , Nehete Jitendra Yadav , Bhambar Rajendra Sudhakar
Published: September 2022

Herbs that have curative properties have been used for a very long time in the practise of traditional medicine. The French bean, scientifically known as Phaseolus vulgaris Linn, is an excellent choice for a meal that's high in both carbohydrates and protein. This plant has a variety of different components, including sugars, proteins, saponins, tannins, and phenolic acid. Phaseolus vulgaris Linn. also has Anti-obesity and anti-urolithiatic properties. In this paper, the phytochemistry and pharmacological characteristics of Phaseolus vulgaris Linn. known as common bean, is  summarised. The plant may also be explored further for its numerous pharmacological properties owing to the extensive range of chemical components it contains, the fact that it is a food crop, and the fact that it is used for natural medicinal purposes. In this work, an effort has been made to present available current status on pharmacology, photochemistry, and botany of the plant. The article also explains the environment in which the plant thrives. All of the data were discovered via searches conducted at the library as well as on Google scholar, PubMed, SciFinder, and Scirus.
case control study on the association between vitamin d deficiency and diabetes mellitus type 2 at tertiary care hospital, Jaipur
Authors: Gupta Devendra Kumar , Gupta Yadvendra , Agarwal Preeti , Sanwelka Madhvi
Published: September 2022

Introduction: Diabetes mellitus refers to a group of common metabolic disorders. Recently, emerging evidence has suggested a role for suboptimal vitamin D status in the etiology of T2DM. This study aimed to determine the association between Vitamin -D deficiency and type 2 Diabetes Mellitus in patients of tertiary care centre, Jaipur. Method and material: This was a hospital based descriptive type of observational study done in Department of Medicine, of a tertiary care hospital in Jaipur, Rajasthan. This study included 100 cases and 100 control. Result: There were 55% males and 45% female among study participants. Out of 200 participants, 160 (80%) subjects are vit D deficient in which 84 (42%) are cases and 76 (38%) are controls, means cases are more deficient for vit D in comparision to controls. Conclusion: Though vitamin D deficiency is prevalent in T2DM and non-diabetic control subjects, its relationship in glycation control or insulin resistance in T2DM subjects could not be confirmed in our study population. This is potentially an important finding for public health, demonstrating that improvement in vitamin D status is one of the factors responsible for better health of the individuals.
Melatonin can enhancement p53 concentration and decrease micronucleus production rate in albino mice
Authors: Hameed Marwa Majeed , Maleek Muthana Ibrahim
Published: September 2022

Melatonin, as an endogenous hormone, is associated with the moderation of the circadian rhythm. Besides controlling the sleep-wake cycle, many physiological functions of melatonin have been identified, such as antioxidant, immune modulating, and anti-inflammatory. The current study was designed to estimate the effect of different doses of melatonin on gene expression of (p53) in serum and micronucleus (MN) in bone marrow stem cells as cytogenetic test. This investigation was conducted at a Research laboratory in the Department of Biology, College of Science, Wasit University and was designed to evaluate the rate of micronucleus (MN) formation as a cytogenetic test and the level of protein p53 as a serological test. Melatonin (5, 10&15) mg/kg was used for seven consecutive days to know their influence on the parameters before mentioned. Results showed a significantly increased in gene expression (protein) of p53 at P≤0.05 for all three doses of melatonin that were used. While Micronucleus production significant decrease at P≤0.05 for the same doses above of melatonin, when all results above were compared with the control group.
Analysis of ocular surface and tear film abnormalities post cataract surgery- small incision cataract surgery V/S phacoemulsification
Authors: Nazm Nazneen , Pisudde Pravin , Mukherjee Sampurna , Kadhane Atul
Published: September 2022

Aim: To evaluate ocular surface and tear film abnormalities post cataract surgery- small incision cataract surgery (SICS) versus phacoemulsification. Material and methods: The present randomised control trial was conducted among 100 patients attending OPD diagnosed with cataract who underwent surgery; age group of more than 40 years were included in the study and randomly divided into 2 groups i.e. Group 1 (who underwent manual SICS) and Group 2 (who underwent Phacoemulsification). Postoperatively, the diagnosis of dry eyes was done by conducting tests viz. Ocular surface disease index questionnaire (OSDI), Schirmer’s test-1, Tear Break up time (TBUT) and impression cytology (IC). Results: Post cataract surgery, mean Schirmer’s value reduced more in group 1 as compared to group 2 at 1 week, 1 month and 3 month with statistically significant difference (p<0.05). Significant deterioration in OSDI was found in both group 1 as well as group 2 after 1 week, 1 month and 3 months of surgery with statistically significant difference (p<0.05). Conclusion: Incidence of dry eye was found to be higher in group that underwent small incision cataract surgery or SICS than phacoemulsification due to tear film instability.
Risk factors for iron metabolic disorders in newly diagnosed B-chronic lymphocytic leukemia patients
Authors: Saleem Hiba Muwafaq , Awad Muthanna Mohammed , Alwan Alaa Fadhil
Published: September 2022

Due to the importance of increasing the incidence conditions of B cell chronic lymphocytic leukemia (B-CLL) that requiring accurate knowledge of the biology behind the pathogenesis and risks of this disease of each individual patient, this study was designed to investigate if hormonal alterations such as Hepcidin, Erythropoietin, and oxidant-antioxidant status may be useful in the understanding of B-CLL development in addition the relationship of these parameters with anemia in advance clinical stage in newly diagnosed patients with B-CLL. This study was conducted on 60 newly diagnosed patients with B-CLL and 30 control group .The socio-demographic information including (age and sex) and clinical data were collected for the period from 20 February until 25 December  2021. The result of the present study showed that out of the 60 newly diagnosed B-CLL patients, 39 was male and 21 was females, with the mean age ( 64.04 ±  5.6 ) years and out of the 30 controls group ,12 was males and 18 was females with the mean age of ( 63.33 ± 4.70) years .therefore, it was a higher prevalence p value ≤0.05 of newly diagnosed B-CLL patients in males (65.0 %) compare to females (35.0 % ).
The effectiveness of myobrace on the treatment of malocclusion and bad habits in children: A systematic review
Authors: Achmad Harun , Horax Sherly , Singgih Marhamah F , Samad Rasmidar , Sumintarti Sumintarti , Rieuwpassa Irene , Harmawaty Harmawaty , Sesioria Arrang
Published: September 2022

Background: Malocclusion is caused by several factors such as sticking out the tongue, biting the lips, sucking the thumb and biting nails, and breathing through the mouth. This bad habit results in malocclusion which can reduce craniofacial development of orthodontic problems in children. One of the treatments for malocclusion in children with orthodontic problems is the use of myofunctional appliances. Myofunctional devices can properly restore orofacial muscles to normal anatomy. One way to overcome this bad habit is to use myobrace. Myobrace is a three-stage device system specifically designed to treat malocclusion and correct bad habits in children. Objective: To search the literature study on the effectiveness of miobrace in early correction of malocclusion development and in overcoming bad habits in children. Method: Data collection was carried out by searching literature on article search sites, namely Pubmed, Cochrane, Wiley, Google Scholar and Science Direct published from 2016 to 2021. The search was carried out from March to April 2021. Systematic exit using the keyword Malocclusion, Myobrace, Orofacial Myofunctional Therapy.
Synthesis caracterizcation of some Schiff bases derived from vanillin containing 1,3,4-thiadiazole moiety
Authors: Ismaeil Eman Ibrahim
Published: September 2022

The aim of this paper, thy schiff bases 1, 3, 4- Thaidiazol organic Compounds with high pharm. acological efficacy, wich play akay important vole in the tratment of urinary track infections, as anti-inflammatory, antimicrobial, anti-bacterial, analgesic, pain relief treatment of diabetics, attiveral, and anti-concer in this research, Vanillen has been used as abioimportant precursor. the Vanillen together, thiosimicarbizid is reated in the Presonce of ethanol to yield the substituted thiesimicarbazid compounds which are used in the preparation of several heterogeneous ving compounds include substituents (1,3,4-thiad; Zol-2-yl) thiesimcarbazide reacts with Sodium acetate in the presence of a lithium steak and the substituted thiosimi carbazide Compounds are also Irapped 4 (5-amino-1; 3; 4- thiadizol-2-yl) 2-methox phenol substituted by its reaction with phosphors Penta Sulfide- the vehicles prepared were diagnosed by the physical and spectral by IR methods of the nuclear magnetic resonance spectrum (H-NMR)
Evaluation of anti-hyperlipidemic activity of Euphorbia Hirta bark against triton ® WR 1339 induced hyperlipidemia
Authors: Khandige Prasanna Shama , Fernandes Zeena , Nayak Prashant , Shubhangi S , Singh Prashant
Published: September 2022

Hyperlipidemia is the major risk factor causing many cardiovascular disorders like myocardial infarction and stroke, atherosclerosis. The world has complimented many herbal substances of therapeutic importance. There are many reports about the use of herbal medicine for reduction of lipid profile and reducing the cardiovascular risk in clinical subjects and experimental pharmacology. The plant Euphorbia hirta bark was evaluated for anti-hyperlipidemic activity by Triton (Superinone, Triton WR-1339), induced hyperlipidemia in rats. This study was carried out on the action of Euphorbia hirtabarkethanolic extracts, a known anti-hyperlipidemic drug, Simvostatin (10 mg/kg body wt.), was taken as a standard drug. The statistical parameters of mean± S.E were employed for the calculation of one way analysis of variance test (ANOVA) and Dunnet’s test for many comparison’s P < 0.05 were considered as significant. The studies were shown. There was a significant (P<0.01) reduction in serum levels in lipid profile experiments. It has reported a significant lower total cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipopreotein (VLDL) and an increase in high density lipoprotein (HDL).The study confirmed that ethanolic extract of Euphorbia hirta bark having significant anti-hyperlipidemic action proving a potential herbal medicine as an alternative to currenttreatment of hyperlipidemia.
Purple sweet extract activates autophagy through enhanced mTOR expression in D-galactose-induced dementia rats
Authors: Widyastuti Ketut , Laksmidewi Anak Agung Ayu Putri , Adnyana I Made Oka
Published: September 2022

The neuropathology of Alzheimer's dementia (AD) is characterized by the buildup of amyloid beta peptide plaques and tau protein in the brain that causes cognitive deficits. The mammalian protein kinase target of rapamycin (mTOR) plays an essential role in controlling the balance of protein synthesis and degradation through autophagy. This study was conducted to determine the role of purple sweet potato water extract in activating autophagy through the mTOR pathway. The study used a randomized posttest-only control group design where 20 male Wistar rats were randomized into the treatment group, and the control group was then induced with d-galactose 100mg/kg BW/day for four weeks. The treatment group was given an aqueous extract of purple sweet potato at 200mg/kg BW/day while the control group was given aquabidest solution for six weeks. The independent t-test showed that the mean mTOR expression in the treatment group (30.30±4.42) was significantly higher (p<0.05) than in the control group (16.89±2.77). Purple sweet potato extract to d-galactose-induced mice increased the autophagy process, characterized by increased mTOR expression. The research implies that the purple sweet potato extract administration can increase the autophagy process and provide neuroprotection effects in rats by d-galactose induction.
Technology and Scientific Authority in United States Abortion Policy: Concerns Over a Mechanistic Approach and a Better Way Forward
Authors: Wilms-Crowe Momo
Published: September 2022

Building on the pragmatist philosophical tradition and work done by scholars in the field of feminist technological studies, this paper considers abortion as a case study to examine how science and technology interact with systems of knowledge, truth, and power. Paying special attention to how technological authority and notions of expertise have influenced public policy and legislative agendas, I consider the role of technological artifacts in shaping our realities and our legal frameworks. Through a historical review of changes in abortion policy and in conversation with various social philosophers, I make the argument that scientific information has not objectively informed abortion opinion and policy, but rather always been a tool of power, reflective of and contributing to larger systemic inequalities. Moreover, because the fundamentally nuanced biology of human fetal development directly conflicts with the legal and moral urge to clearly demarcate personhood from non-personhood, I outline why any attempts to define personhood or viability based purely on biological evidence is arbitrary, deceptive, and ultimately inappropriate. For this reason, I conclude by advocating for the use of a more contextual approach to policy making, considering larger sociopolitical dynamics of gendered power and oppression as well as the lived experiences of those impacted directly by the legislation. In the current political moment, technology is playing an increasingly large role in our lives, and access to abortion and reproductive rights are being actively threatened by those in the highest ranks in the US government. This paper attempts to provide a deeper understanding of the philosophical journey our society took to reach this junction and suggest a better path forward, centering the values of democracy, dignity, and justice.
Behavioral and Neural Predictors of Individual Differences in Concept Generalization
Authors: Iwashita Takako
Published: September 2022

Concept learning involves linking related pieces of information to a shared label, such as learning that furry creatures that bark are called “dogs.” People vary in how well they learn concepts and apply them to new situations (generalization). What factors drive these individual differences? In the present study, we tested whether stable aspects of intelligence or transient activations in the brain best predicted concept generalization abilities. To measure aspects of intelligence, subjects underwent an assessment that included measures of working memory, processing speed, perceptual reasoning, and verbal comprehension, which could be combined into an overall IQ. Subjects also completed a concept generalization task while undergoing functional MRI, allowing us to measure activations in brain regions that are part of the explicit rule-learning system (hippocampus, prefrontal cortex) or part of an implicit system that learns without awareness (caudate, posterior visual cortex). To elucidate the shared or dissociable roles of behavioral and neural predictors in concept generalization, we tested the relationship between accuracy in concept generalization and individual differences in measures of intelligence and activation in each brain region of interest. Behaviorally, we found that overall IQ, but not its subcomponents, predicted concept generalization abilities. Neurally, we found that only the activation in the hippocampus predicted concept generalization abilities. Finally, we found that IQ and hippocampal activation each predicted concept generalization independent of each other, indicating that they represent two separate processes that both contribute to generalization success. These results show dissociable contributions of behavioral and neural predictors of concept generalization, suggesting that both stable cognitive abilities and transient brain states influence the ability to learn new concepts.
The Nuclear Family and Gender Roles in Oregon’s Venereal Disease Campaign: 1911-1918
Authors: Fellman Dimitra
Published: September 2022

The Social Hygiene Society of Portland, Oregon (later renamed the Oregon Social Hygiene Society - or OSHS) was founded in 1911 in order to combat venereal disease in the city and eventually across the state. Oregon’s efforts were part of the broader social hygiene movement taking place across America during the second decade of the twentieth century, which most notably advocated for an equal standard of chastity for men and women. Despite this single standard, promiscuous women (women engaged in premarital sex or sexual relations with multiple sexual partners) were systematically persecuted and punished while men were not. While a large amount of existing scholarship focuses on how the social hygiene movement targeted prostitutes and not the men seeking their services, little work has been done to investigate how the movement viewed husbands and wives within the nuclear family and whether partnerships were equal when it came to combating venereal disease. This paper investigates how the social hygiene campaign in Oregon from 1911 to 1918 viewed the nuclear family and conceptualized parental duties in combating venereal disease. It also analyzes how those duties equalized husbands and wives while simultaneously reflecting social gender norms of the time that relegated women to the home
Exploring Practical Village Planning in the Context of Territorial Spatial Planning - An Example of Baozi Village in Baihe Town
Authors: Lu Peng , Zhang Wanying
Published: September 2022

While the country is formulating and implementing the rural revitalisation strategy, China's territorial spatial planning system has been initially established, new opportunities for rural development and construction have emerged, and great changes and challenges have emerged in rural planning. Under the dual influence of the rural revitalization strategy and the construction of the territorial spatial planning system, the need for the preparation of rural planning has also changed. The article takes the planning of Baozi Village in Baihe Town as an example, analyzes the problems through the current situation from the perspective of "multi-regulation", and proposes corresponding solutions to explore some experiences for future practical village planning.
Research on Subway Operation Safety Platform Model Based on Blockchain and Internet of Things
Authors: Guo Cong , Qiu Chuan , Gong Xingjun , Zhao Yanghao , Yu Yongqiang
Published: September 2022

With the continuous and rapid increase in the scale of subway operation, the security situation faced by the operating units is becoming increasingly severe. Based on the analysis of the characteristics of subway operation and the current situation of information construction, this paper deeply analyzes the main problems of subway operation safety information construction. Aiming at the problems of poor data circulation, difficult supervision, distrust, fear of leakage, poor timeliness, poor quality and insufficient certificates, this paper puts forward the construction requirements of subway operation safety platform. The platform model is designed from three aspects of block chain platform, platform logic architecture and Internet of Things forensics, and the new mode of safe and efficient management of subway operation is explored.
Transformation and Development Path of China’s Thermal Power Generation Industry under Dual Carbon Goal
Authors: Li Zepeng
Published: September 2022

In the next few decades, the transformation and development direction of China’s power industry is achieving dual carbon goal, thermal power units with high installed capacity and large carbon emissions are the main targets of carbon emission reduction. This paper expounds the connotation of dual carbon goal in power industry, and then discusses the transformation and development path of China’s thermal power generation industry under the dual carbon goal from 3 directions: carbon mitigation from the source, carbon mitigation from the sink and improvement of the grid’s ability to absorb new energy power. The results show that carbon mitigation from the source can be achieved through co-firing biomass with coal for thermal power generation and energy saving of thermal power generating unit under all working conditions. Post-combustion carbon capture is the mainstream technology to improve the carbon dioxide absorption capacity of the sink. Optimizing the flexible operation control strategy of coal-fired power plants can improve the absorption capacity of the grid for new energy power. This paper can provide reference for researchers who want to understand the development trend of thermal power generation industry in China.
Analysis on the Investment Environment and Investment Problems of Manufacturing Industry in Anhui Province
Authors: Ren Zhian , Yan Liu , Zhou Zejiong
Published: September 2022

Anhui has gradually changed from a traditional agricultural province to a new manufacturing province in recent years, and has made proud achievements. This paper attempts to take the investment situation of Anhui manufacturing industry as the starting point to analyze the hard environment and soft environment of Anhui manufacturing investment. The results show that Anhui has the conditions to promote manufacturing investment in natural resources, human resources, infrastructure and scientific and technological innovation. However, after further understanding the development status of Anhui manufacturing investment, some problems have also been found, such as the reduction of investment scale, slow recovery speed, unreasonable source of funds, large investment gap between regions, and low efficiency of resource utilization. In order to solve the above problems, this paper puts forward countermeasures from the aspects of investment intensity, investment confidence, financing channels, regional gap, investment efficiency, etc., in order to speed up the construction of a strong manufacturing province in Anhui.
Research on Scientific Gas Extraction Technology Based on Engineering Thinking
Authors: Wei Qiao
Published: September 2022

Due to the complex and changing regional tectonics of the coal-bearing basins in China, it makes it more difficult of gas extraction; in addition, it seriously affects the gas governance effect of the single way of hole arrangement and other problems including the poor quality in hole drilling and sealing, hole collapse, downward hole ponding and air leakage of pipe network and so on. In view of this, it has proposed to establish spatial digital model by making use of the theory of transparent space geophysics to precisely identify and divide the regional tectonics. Based on engineering thinking, it depends on artificial intelligence, big data cloud computing technology and equipment in multi-factor identification method for scientific investigation of gas extraction radius, hole-drilling design, construction, management and extraction standard evaluation and other comprehensive control. It aims to realize scientific, procedural and precise packaged technology for gas extraction. This technology has filled the gas of scientific packaged gas extraction technology application in China.
Damage to Rocks by Eccentric Uncoupled Charge Explosion Loads
Authors: Bai Mingxiao
Published: September 2022

In the process of tunnel excavation, the blasting technology is one of the commonly used tunnel excavation methods. The blasting technology is mainly divided into smooth blasting and presplitting blasting. In the process of blasting, in order to prevent excessive damage caused by explosive blasting, the blasting is often carried out by means of uncoupled charging. In the previous studies, the explosive and the blast hole were mainly placed concentrically, while in the actual engineering, the charge often exists in the form of eccentricity. In this study, LS-DYNA is used to establish three-dimensional models of concentric charge and eccentric charge respectively for numerical simulation of blasting, and the whole process of uncoupled charge blasting is reproduced. Based on the damage cloud diagram, hole wall pressure and hole wall vibration velocity obtained by simulation, the damage caused by blasting under two different charging conditions is analyzed and compared.
A Review of The Theory of Water Evaporation in Soil and The Study of Soil-Water Characteristic Curve
Authors: Wang Ruipu , Yang Chenxia , Li Hua , Li Renjie
Published: September 2022

The theory of water evaporation in soil and the soil-water characteristic curve are the core of unsaturated soil research, and have very important guiding significance for engineering practice. This paper uses the theoretical summary method to summarize the theory of water evaporation in soil and the related theory of soil-water characteristic curve. The results show that the water evaporation in the soil is the result of the combined action of internal factors and external factors. Matrix suction is the core of the soil-water characteristic curve. There are many factors that affect the soil-water characteristic curve. The mineral composition and pore structure of soil are the two most essential influencing factors, and other influencing factors mainly play their role through these two factors.