bluuebunny/crossref_metadata_2025 huggingface dataset:
From not-for-profit to profit-driven independent schools through the eyes of some of the stakeholders
Authors: Breedt Ilze , Beckmann Johan , Du Plessis Andre
Published: December 2021

This qualitative study sought to explore the experiences of stakeholders at independent schools during and after the transition from a not-profit governance approach to a for-profit governance approach after a change of ownership. Section 29(3) of the Constitution of South Africa provides that “everyone has the right to establish and maintain, at their own expense, independent educational institutions” subject to certain requirements to ensure quality education (RSA, 1996a).
Such schools have become an integral part of the South African education system. However, some independent schools represent the notions of investment and profitable business and companies listed on the Johannesburg Stock Exchange (JSE) have started to invest in the independent school sector. The requirements of good governance, as stipulated in the King III Report on Corporate Governance for South Africa 2009, were used as the conceptual framework for this study.
Two independent schools that transitioned from a not-for-profit approach to a profit-driven governance approach were sampled. It was found that the experiences of the principals and management teams of the participating schools differed significantly from the experiences of the teachers and parents at these schools. A school is part of a community and when a company takes over a school, they need to make sure the communication to all stakeholders is clear and transparent.
Playing games in a masters class: Experiences of student educational psychologists
Authors: Fourie Jean , Wilson Claire
Published: December 2021

Playing authentic educational games can support learners of all ages and abilities, particularly those with special educational or remedial needs. Playing games in cooperative groups allows learners to relate socially, motivate each other competitively and rehearse schoolwork. Literature mostly covers computer games rather than real-life educational games.
This study explored student educational psychologists’ experiences in creating and playing authentic educational games to facilitate learning for children with special educational needs. In pairs, the students constructed educational games from everyday recyclable material with the purpose of reinforcing concepts related to phonics, spelling, reading and mathematics. The games required small groups of learners to play together with minimal teacher facilitation. Working with a generic, qualitative, interpretive research design, the experiences of this cohort (n=29) of Master’s students were gleaned from their reflective writings and the researcher’s journal. Thematic content analysis was used to analyse the data and identify the emergent themes within the theoretical framework of game-based learning.
The findings indicated that authentic self-made educational games exhibited all the required features conceptualised in the theory of gameplay. Learning through play created experiences that are fun, motivating and have learners requesting more. Authentic educational games provided emotional and educational support. Playing educational games is a supportive adjunct to remedial interventions in the therapeutic context.
Twenty years into the new millennium: How integrated is Mathematics, Physics and Computer Science at secondary school level?
Authors: Basson Ilsa
Published: December 2021

Twenty years into the millennium, the world has been confronted with a pandemic that has had an immeasurable impact on the workplace, learning environment and related technologies. Technology and technological advancements are founded on three disciplines, namely Physics, Mathematics and Computer Science. Internationally, an integration of the curricula of these disciplines are promoted in the education space, as an effective way to achieve 21st century capabilities that lately includes computational thinking. This study explores the changes in the content and alignment of the three subjects in the South African secondary school system from an interdisciplinary framework perspective. Textbooks, curriculum documents and planning calendars provided the information for the content analysis. The content in Physics and Mathematics have remained basically the same, with a few topics removed from Physics and some added to Mathematics. Information Technology has replaced Computer Science, with significant changes in content in alignment with developments in computing technology. No clear indication of an alignment between the disciplines could be found, which, to a certain extent, puts South Africa outside the international frame. The basic education system appears to run an assessment-driven curriculum in Mathematics, Physical Sciences and Information Technology. This system produces poor results and seemingly does not allow for interdisciplinary skills development.
The influence and value of science and technology in the education systems of South Africa and Russia
Authors: Maree Niconette , Vos Deon
Published: December 2021

The aim of this study was to identify the influence of technology on the education systems of South Africa and Russia. The study has brought to light the importance of technology, and that it contributes to the increase of quality of education. The correct application of relevant technology in education can be used as valuable support to education delivery, it can stimulate creativity, contribute to the development of higher-order cognitive thinking skills, assist learners to develop technological skills and finally it can help economic growth in the country. Moreover, the study created an opportunity to highlight differences and similarities in the purpose of technology, the access to and distribution thereof, the implementation thereof in classrooms and the challenges in terms of implementing them successfully. By using a comparative method, the researchers had the opportunity to identify gaps in the research for future studies, methods for the implementation of technology and universal challenges, such as the digital divide. This study has provided ample evidence of the value that technology adds if successfully implemented and how much value it can bring towards an education system. This is also the reason why an education system of any country should ensure the sustainability of the implementation of technology in the system. It is important that the education systems of both South Africa and Russia proceed to directly identify and address gaps in their approaches to implementing technology. It is also important for these countries to release more relevant data and policies regarding this topic, specifically in education. Although the role of the BRICS organisation is identified as the science and technology innovation (STI) initiative, there are no clear indicators in policy documents or references to technology in education. Moreover, looking specifically at the BRICS countries, it is clear that they have made strides in addressing such challenges as stipulated in the literature. To conclude, this research can be used to further address the challenges and limitations that were identified in the study in order to assess the future impact of technology on an education system.
Turning constraints into opportunities: Online delivery of communication skills simulation sessions to undergraduate medical students during the COVID-19 pandemic
Authors: Abraham Reina
Published: December 2021

The COVID-19 pandemic impacted higher-learning institutions. Communication skills training in medical education needed innovative solutions to adjust to the situation. In times of change, evaluation channels should be developed, and any problems raised by learners and educators should be responded to rapidly. A remotely facilitated communication skills simulation-based training programme was piloted by the clinical skills laboratory tutors using Zoom as the online platform. The goal of the pilot session was to establish a communication skills training strategy remotely, to test an online session using the defined online platform and to assess its effectiveness. Though locally facilitated face-to-face simulationbased training as the conventional format is easier to use and experience, training on virtual simulation-based communication skills enabled through the online portal has been described by participants as both feasible and effective. The results show that an efficient educational environment can be provided by remote simulation of communication skills. An important requirement for learner engagement with remotely facilitated simulation-based training is the development of contextual understanding, multiple exposures and a respectful learner-teacher relationship. Any negative impact of remotely facilitated simulation-based training may be concealed by an overarching high perceived value of simulation-based trainings in general. This pilot online simulation programme shows the value of using this modality and lays the foundation for communication skills teaching during future disasters. There is the need to consider how online simulation can be sustained after the pandemic and not just returning to the conventional face-to-face teaching and learning.
The influence of learner behaviour on beginner teachers’ perceptions of their own credibility
Authors: Reddy Tanita , Woest Yolandi
Published: December 2021

Traditionally, teacher credibility has been influenced by how others perceive them. However, exploring teachers’ own perceptions of their credibility through the observation of learner behaviour may prove to be meaningful to teacher credibility. The aim of this study was to explore Intermediate Phase beginner teachers’ perceptions of their own credibility based on displayed learner behaviour in their classrooms. This qualitative study was presented through a case study research design. Eight Intermediate Phase beginner teachers were purposively selected. The data collection techniques used were interviews and observations. Semi-structured interviews and a researcher journal were used as data collection instruments. The data were analysed using inductive thematic data analysis. The conceptual framing of this study was underpinned by a modified theoretical model developed by McCroskey, Valencic and Richmond (2004). The findings showed that teachers’ perceptions of their own credibility were fluid as they engaged with various learners’ behaviour, which was used as a form of feedback during lessons and this feedback impacted teachers’ reactions and decisions to classroom situations. Ultimately, teachers’ perceptions of their own credibility focused on their immediacy, trustworthiness, competence and dynamism displayed in their practices.
The juxtaposition of rights and responsibilities: children’s experiences and perceptions
Authors: Van Aardt Linda , Venketsamy Roy , Thuketana Nkhensani Susan , Joubert Jacomina Christina
Published: December 2021

Rights and responsibilities are enshrined in the Constitution of the Republic of South Africa but are disregarded in many ways in the education of young children. This article focuses on comparing the experiences and perceptions of Grade 3 children of their rights and responsibilities across diverse school settings. The comparison of data sets highlighted reciprocity in children’s experiences and showed challenges and gaps in children’s education of rights and responsibilities. This research was qualitative in nature, using a multiple case study design with ninety-six (n=96) participating children. Data gathering occurred through interviews, observation, documents, field notes and visual artefacts made by the participating children. The findings were that education firstly advances children’s understanding and knowledge of their rights and responsibilities. Secondly, basic needs of children have a significant effect on their understanding of their rights and responsibilities with the emphasis on rights. Children’s perceptions of their rights and responsibilities were juxtaposed to assist in finding similarities and differences in their perceptions. Thirdly, the participant children understood that people have needs and rights; they communicated that these rights must be recognised to safeguard a sustainable standard of life.
Entrevista a Mariana Rodríguez
Authors: Escalante Andrés A.
Published: December 2021

La UPC fue co-fundada por los mismos fundadores de Cibertec: David Fischman, Alfredo Miro Quesada, Chiqui Bancalari y yo. Varias razones nos llevaron a contemplar la creación de una universidad.
The Role of Chest Computerized Tomography in Covıd-19 Diagnosis in Emergency Department Settings
Authors: BEKGÖZ Burak , KAHRAMAN Fatih , USUL Eren , ŞAHİN Ali , ŞAN İshak
Published: December 2021

In this study, the chest computed tomography (chest CT) findings of patients with suspected COVID-19 admitted to the

emergency department were examined, and it was evaluated whether chest CT should be performed in each patient with suspected

COVID-19. Patients with suspected COVID-19 and who had chest CT were included in the study. Swab samples were taken from the

throat and nose of the patients for RT-PCR. Chest CT was applied to the patients according to the physician's decision. A team of 5

radiologists evaluated the chest CT reports. 251 patients were included in the study. In the chest CT of 154 patients (61.4%), findings

compatible with COVID-19 pneumonia were found. The number of patients who were found to have COVID-19 by PCR test result was

138 (55.0%). The most common pneumonia finding was found to be ground glass (55.8%) Most of the patients had findings in both

lungs (25.9%). Less frequently, the right lung (23.1%) was affected. The least affected was the left lung (14.7%). The most frequently

affected part of the left lung was the lower lobe. In emergency services, the use of chest CT after the physical examination of the

patients with suspected lung involvement may be useful in the diagnosis of COVID-19.
The Survival Efficiency of Initial Surgical Treatment in Stage IIIa-N2 Positive Non-Small Cell Lung Cancer
Authors: BEYOGLU Muhammet Ali , GULHAN Selim Şakir Erkmen , ÖZTÜRK Ayperi , ACAR Leyla Nesrin , ŞAHİN Mehmet , FİNDİK Gokturk
Published: December 2021

​ Objective: The role of surgical treatment in the multimodal treatment of stage IIIA-N2 positive non-small cell lung cancer (NSCLC) patients is a matter of debate. We aim to investigate initial surgical treatment's survival efficiency in patients with IIIA N2 positive NSCLC.Methods: The patients treated for stage IIIA N2 positive NSCLC in a single center between January 2009 and December 2014 were retrospectively analyzed. A total of 134 patients with 5 cm tumors in diameter or less and without involvements of the chest wall, mediastinal pleura, phrenic nerve, recurrent laryngeal nerve, pericardium, heart, diaphragm, vertebra, esophagus, large vessel invasion, and satellite nodule were detected. Of these patients, initial surgical treatment before chemoradiotherapy was performed in 72 (Group 1), while definitive concurrent chemoradiotherapy was performed in 62 patients (Group 2). Each patient's gender, age, physical performance status, tumors size, pathological diagnosis, lung resection types, and long-term survival data were evaluated.Results: No statistically significant difference was found in patients' gender, physical performance, tumor size, and tumor histology. Survival rates were higher among patients aged ≤65 years and higher in Group 1 than Group 2. While one-, three, five-, and seven-year survival rates were detected as 86.1%, 62.5%, 41.6%, and 31% in Group 1, respectively, the rates were observed to be as 77.4%, 30.6%, 10.8%, and 6.7% in Group 2, respectively. However, no difference was seen between patients' survival rates with single and multiple ipsilateral mediastinal lymph node metastases.Conclusion: Despite those advocating surgical treatment after neoadjuvant chemotherapy in treating stage IIIA N2 positive patients, others supporting surgical treatment should initially be performed. When conducted as the first step, surgical treatment achieves significant increases in survival.
Microautologous	Fat	Transplantation (MAFT)	sebagai	Rekonstruksi	Lanjutan	pada	Kasus	Deformitas	Maksilofasial	Pasca	Trauma
Authors: Perdanakusuma Ardea , Primawati Ariani , Dr Budiman
Published: December 2021

Latar Belakang: Teknik Microautologous Fat Transplantation (MAFT) merupakan sebuah metode yang relatif baru untuk memindahkan lemak dari lokasi tubuh tertentu ke lokasi tubuh yang diinginkan dengan suatu alat khusus. Teknik transfer lemak sebenarnya sudah dilakukan sejak tahun 1893 namun terkendala dengan masih banyaknya lemak yang diresorpsi sehingga memerlukan beberapa kali tindakan ulangan. Teknik Microatutologus Fat Transplantation menggunakan MAFT Gun pertama kali dilakukan oleh Lin et al. pada tahun 2006. Teknik ini telah menunjukkan hasil yang baik dalam bidang estetik maupun rekonstruksi menggantikan teknik dermofat graft yang bersifat lebih invasive. Deformitas pada wajah akibat dari hilangnya sejumlah volume lemak dapat diatasi dengan MAFT Gun yang bersifat minimal invasif. Pada tulisan ini dilaporkan satu kasus penanganan deformitas maksilofasial pasca reposisi dan fiksasi fraktur tulang wajah dengan Microautologous Fat Transplantation sebagai salah satu modalitas. Pasien dan Metode: Jaringan lemak diambil dengan spuit 60 cc tekanan negatif kemudian dilakukan sentrifugasi dengan kecepatan 3000 rpm selama 10 menit untuk memisahkan komponen lemak dan plasma. Lapisan lemak murni selanjutnya ditransplantasikan pada area wajah menggunakan MAFT Gun di bawah mata 3.5 ml, pipi 20.5 ml, dagu 3 ml, dan pelipis 1 ml. Hasil: Lama tindakan 2 jam 30 menit, prosedur anestesi sedasi sedang dan blok nervus infraorbitalis, nervus mentalis, dan nervus supraorbitalis, dan nervus supratrochealis ipsilateral. Deformitas dapat teratasi, longterm follow up 3 bulan pasca operasi tidak banyak jaringan lemak yang diresorpsi, sehingga penampilan masih baik. Kesimpulan: Teknik MAFT Gun merupakan prosedur yang efektif untuk memperbaiki kontur wajah, peremajaan wajah, memperbaiki area yang cekung, dan mengembalikan volume termasuk mengoreksi deformitas wajah akibat fraktur maksilofasial pasca reposisi fraktur maksilofasial yang kurang sempurna. Prosedur yang dilakukan relatif tidak invasif. Jaringan lemak dapat diambil dari berbagai area tubuh yang memiliki jaringan lemak berlebih. Menggunakan MAFT Gun yang telah tersertifikasi, proses transfer lemak dapat dilakukan secara akurat dan konsisten. Hasil MAFT cukup memuaskan bagi pasien, sehingga memungkinkan prosedur MAFT menjadi alternatif solusi untuk mengoreksi deformitas maksilofasial pasca reposisi dan fiksasi yang mungkin hanya memerlukan tindakan touch up satu sampai dua kali saja
Ethics of local government heads: A study of leadership in Surabaya, Bandung, and Purwakarta, Indonesia
Authors: Taufik Mohammad , Irawan Bambang , Khairina Etika , Fadhlurrohman Mochammad Iqbal , Akbar Paisal
Published: December 2021

The most significant aspect of a leader’s behavior is ethics because it is a guideline for interacting, acting, and involving in government in an ethical manner without abusing power. This article aims to find out how the ethics of regional heads are applied in the administration of regional government. The research method used was qualitative with a literature study approach. Data collection was done by literature study by collecting various materials from books, journals, research results, and mass media (news). The results of research conducted on three districts/cities in Indonesia involving three leaders of the Mayor of Surabaya, the Mayor of Bandung, and the Regent of Purwakarta in 2015 show some real examples of regional heads who apply ethical values in their leadership, which can be seen from their performance and competence as well as ideas (innovation) and relationships with the community. It has gone well by applying ethical principles in its performance such as accountability, transparency, legal assurance, and justice. Competence in leadership includes the application of ethical values including emotional intelligence, self-management, social awareness, and relationship management. This study concludes that government ethics greatly influence the implementation and desired results, as well as on leadership, which will affect the performance carried out.
Thermoelectric and mechanical performances of ionic liquid-modulated PEDOT:PSS/SWCNT composites at high temperatures
Authors: Deng Wenjiang , Deng Liang , Hu Yue , Zhang Yichuan , Chen Guangming
Published: December 2021

Significant progress has been achieved for flexible polymer thermoelectric (TE) composites in the last decade due to their potential application in wearable devices and sensors. In sharp contrast to the exceptional increase in TE studies at room temperature, the mechanical performance of polymer TE composites has received relatively less attention despite the significance of the application of TE composites in high-temperature environments. The TE and mechanical performances of flexible poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)/single-walled carbon nanotube (PEDOT:PSS/SWCNT) composite films with an ionic liquid (IL) (referred to as “PEDOT:PSS/SWCNT-IL”) at high temperatures are studied in the present work. The fabricated composite films show increasing TE performance with increasing temperature and SWCNT content. The maximum value of the power factor reaches 301.35 μW m-1 K-2 at 470 K for the PEDOT:PSS/SWCNT-IL composite. Furthermore, the addition of the IL improves the elongation at break of the composites compared to the IL-free composites. This work promotes the advancement of flexible polymer TE composites and widens their potential applications at different temperature ranges.
Pemberdayaan Masyarakat Loano Di Masa Pandemi Covid-19
Authors: Fitri Noor , Purwaningsih Tuti
Published: December 2021

Desa Loano merupakan daerah strategis antara bandara Yogyakarta Internasional Airport (YIA) dan Candi Borobudur. Potensi pariwisata dan souvenir Desa Loano sangat besar. Souvenir yang bisa dikembangkan antara lain produk berbasis minyak atsiri. Saat ini, sebagian besar masyarakat Desa Loano adalah petani konvensional. Masyarakat Loano belum memiliki kesadaran yang tinggi akan potensi tanaman atsiri di sekitar mereka yang dapat diolah menjadi minyak atsiri yang mempunyai nilai jual lebih tinggi. Selain itu minyak atsiri tersebut dapat digunakan untuk membuat produk berbasis minyak atsiri seperti sabun cair cuci tangan, sabun cuci piring, handsanitizer, diffuser aroma terapi, lilin aroma terapi. Permasalahan tersebut diakibatkan tingkat kesadaran dan pengetahuan masyarakat masih rendah, disamping itu tidak adanya penyuluh dan pendamping tentang pengembangan potensi pertanian yang ada. Berdasarkan permasalahan tersebut, perlu dilakukan program pemberdayaan masyarakat Desa Loano untuk meningkatkan ekonomi dan kesejahteraannya dengan program KKN-PPM. Solusi yang diterapkan yaitu: (1) Pengolahan bahan baku rempah menjadi produk minyak atsiri; (2) Pembuatan produk turunan berbasis minyak atsiri; (3) Pendampingan manajemen usaha produk berbasis minyak atsiri; serta (4) Pengadaan teknologi tepat guna. Kegiatan KKN PPM yang telah dilakukan berhasil meningkatkan skill masyarakat Loano dan menghasilkan produk berbasis minyak atsiri. Produk berbasis minyak atsiri dapat menjadi salat satu program BUMDES untuk meningkatkan kesejahteraan masyarakat.
JOHN LOCKE: DA EPISTEMOLOGIA À INTERPRETAÇÃO BÍBLICA
Authors: Santos Antônio Carlos dos
Published: December 2021

O objetivo deste texto é articular a epistemologia de John Locke com a sua interpretação bíblica. Pretendemos mobilizar os conceitos de razão, crença, revelação e de milagre no seu Ensaio sobre o entendimento humano com alguns textos de Locke voltados para sua hermenêutica bíblica. Nossa hipótese de trabalho é que não há diferença metodológica entre o trabalho de interpretação epistemológica daquele que lida com a exegese bíblica. O procedimento é rigorosamente o mesmo. Para fornecer maior inteireza argumentativa ao texto, ele contém duas partes. Na primeira, analisaremos os conceitos de razão, fé e revelação, presentes no Essay. Na segunda, pensaremos sobre as recomendações de Locke para ler os textos sagrados, em A Paraphrase e, finalmente, o problema dos milagres, sobretudo, no Miracles. Assim, entendemos que a leitura do Essay é propedêutica para decifrar os textos sagrados. Esperamos que este texto possa colaborar com os estudos de Locke no Brasil, de modo particular, no que concerne à epistemologia da crença.
ARISTÓTELES LENDO OLAVO DE CARVALHO: DE UMA RETÓRICA ERÍSTICA
Authors: Mathias de Alencar Cesar Augusto
Published: December 2021

Este estudo pretende apresentar uma interpretação acerca da concepção de discurso que explica e justifica a atuação textual e midiática de Olavo de Carvalho, tendo como ponto de partida sua obra sobre a pretendida teoria dos quatro discursos em Aristóteles. A partir da demonstração de que não se trata de uma interpretação decididamente aristotélica, constatamos ser necessário considerá-la como uma reflexão programática de Carvalho sobre certo uso do discurso para fins políticos, que chamo de retórica erística, e cuja intenção se define pelo estabelecimento do saber e do livre debate de ideias como inescapáveis à lógica persuasiva do embate erístico, aquele em que o que conta é vencer o debate sem precisar ter razão. Essa intenção é confirmada pelo cotejo com as obras mais decisivas ao tipo de exercício de poder pretendido pelo autor, e que nos esclarecem sua satisfação em insuflar o impedimento do debate por via dupla: a de forjar, para seus leitores, uma impressão de que possuem a verdade que os situa acima das intelectualidades de todo tipo; e a de, por conta dessa impressão, atomizá-los na verborragia de sua opinião única. O efeito pedagógico dessa retórica erística é imbuir seus alunos de uma missão política, claramente circunscrita ao ódio pelo comunismo e pela verdade enquanto nascida não do silêncio individual, mas do diálogo entre interessados pelo saber.
Atomistic modeling of the parameters of the critical region of gold using the liquid-vapor coexistence curve
Authors: Mazhukin Vladimir Ivanovich , Koroleva Olga Nikolaevna , Demin Mikhail Mikhailovich , Aleksashkina Anna Andreevna
Published: December 2021

The liquid-vapor coexistence curve for gold was obtained by molecular dynamics (MD) modeling and the critical parameters were determined: temperature, density and pressure. The interaction potential of particles of the “embedded atom” family EAM is used. The critical temperature Tcr was determined from the results of MD simulation using the method of the average cluster size in the critical region. To clarify the value of the critical density, the empirical rule of the rectilinear diameter was used. The comparison of the simulation results of this work with the results of the assessment of the critical parameters of gold by other authors using different approaches.
DETERMINAN RETURN ON ASSETS BANK BNI SYARIAH: PENDEKATAN ERROR CORRECTION MODEL
Authors: Marlistyawati Putri Deby , Maulida Nurhidayati  , Nurul Khasanah
Published: December 2021

Return on Assets at BNI Syariah banks has shown poor performance. If this condition continues, it can have a destructive impact and result in many losses that must be borne. The study was conducted to determine the effect of mudharabah deposits, equity, and size on Return on Assets at BNI Syariah Bank. The research was conducted with a quantitative approach on quarterly data published by BNI Syariah, OJK, and BI for 2012-2019. The analysis technique uses the Error Correction Model (ECM). The results obtained indicate that mudharabah deposits and equity in the short and long term do not affect ROA. Size in the short term has no effect but in the long term affects ROA. Simultaneously, mudharabah deposits, equity, and size affect ROA both in the short and long term. The contribution amount given is 31.74% in the short term and 49.51% in the long term. BNI Syariah Bank can further increase customer interest in deposits, expand market share in larger-scale business units and the general public, and use promotional media more creatively according to the digital era.

Return on Assets pada bank BNI Syariah telah menunjukkan performansi kurang baik. Jika kondisi ini terus berlangsung dapat berdampak buruk serta berakibat pada besarnya kerugian yang harus ditanggung. Penelitian dilakukan untuk mengetahui pengaruh deposito mudharabah, ekuitas, dan size terhadap Return on Assets pada Bank BNI Syariah. Penelitian dilakukan dengan pendekatan kuantitatif pada data triwulan yang dipublikasikan oleh BNI Syariah, OJK dan BI periode 2012-2019. Teknik analisis menggunakan Error Correction Model (ECM). Hasil yang diperoleh menunjukkan bahwa deposito mudharabah dan ekuitas pada jangka pendek maupun jangka panjang tidak berpengaruh pada ROA. Size dalam jangka pendek tidak berpengaruh tetapi dalam jangka panjang berpengaruh pada ROA. Secara simultan, deposito mudharabah, ekuitas dan size berpengaruh pada ROA baik dalam jangka pendek maupun jangka panjang. Besarnya kontribusi yang diberikan adalah 31,74% pada jangka pendek dan 49,51% pada jangka panjang. Bank BNI Syariah dapat lebih meningkatkan minat nasabah pada deposito, memperluas market share pada unit usaha skala lebih besar serta masyarakat umum  lainnya dan penggunaan media promosi sesuai era digital dengan lebih kreatif.
Preventing Non-attendance in Outpatient Appointments: Predictive Model Development, Validation, and Clinical Assessment
Authors: Valero-Bover Damià , González Pedro , Carot-Sans Gerard , Cano Isaac , Saura Pilar , Otermin Pilar , Garcia Celia , Gálvez Maria , Lupiáñez-Villanueva Francisco , Piera-Jiménez Jordi
Published: December 2021

Background: Non-attendance to scheduled hospital outpatient appointments may compromise healthcare resource planning, which ultimately reduces the quality of healthcare provision by delaying assessments and increasing waiting lists. We developed a model for predicting non-attendance and assessed the effectiveness of an intervention for reducing non-attendance based on the model.Methods: Candidate models were built using retrospective data from appointments scheduled between January 1, 2015, and November 30, 2018, in the dermatology and pneumology outpatient services of the Hospital Municipal de Badalona (Spain). The predictive capacity of the selected model was then validated prospectively with appointments scheduled between January 7 and February 8, 2019. The effectiveness of selective phone call reminders to patients at high risk of non-attendance according to the model was assessed on all consecutive patients with at least one appointment scheduled between February 25 and April 19, 2019. Patients identified by the model as high risk of non-attendance were randomly assigned to either a control (no intervention) or intervention group, the last receiving phone call reminders one week before the appointment.Results: Models were trained and selected using 33,329 appointments in the dermatology service and 21,050 in the pneumology service. Average results for specificity and balanced accuracy for the prediction of non-attendance were 79.90% and 73.49% for dermatology, and 71.38% and 64.61% for pneumology outpatient services. The prospective validation showed a specificity of 78.34% (95%CI 71.07, 84.51) and balanced accuracy of 70.45% for dermatology; and 69.83% (95%CI 60.61, 78.00) for pneumology, respectively. The effectiveness of the intervention was assessed on 1,311 individuals identified as high risk of non-attendance according to the selected model. Overall, the intervention resulted in a significant reduction in the non-attendance rate to both the dermatology and pneumology services, with a decrease of 50.61% (p<0.001) and 39.33% (p=0.048), respectively.Conclusions: The risk of non-attendance can be adequately estimated using patient information stored in medical records. The patient stratification according to the non-attendance risk allows prioritizing interventions, such as phone call reminders, to effectively reduce non-attendance rates.
DR-VIDAL - Doubly Robust Variational Information-theoretic Deep Adversarial Learning for Counterfactual Prediction and Treatment Effect Estimation
Authors: GHOSH SHANTANU , Feng Zheng , Bian Jiang , Butler Kevin , Prosperi Mattia
Published: December 2021

Determining causal effects of interventions onto outcomes from observational (non-randomized) data, e.g., treatment repurposing using electronic health records, is challenging due to underlying bias. Causal deep learning has improved over traditional techniques for estimating individualized treatment effects. We present the Doubly Robust Variational Information-theoretic Deep Adversarial Learning (DR-VIDAL), a novel generative framework that combines two joint models of treatment and outcome, ensuring an unbiased estimation even when one of the two is misspecified. DR-VIDAL uses a variational autoencoder (VAE) to factorize confounders into latent variables according to causal assumptions; then, an information-theoretic generative adversarial network (Info-GAN) is used to generate counterfactuals; finally, a doubly robust block incorporates propensity matching/weighting into predictions. On synthetic and real-world datasets, DR-VIDAL achieves better performance than other non-generative and generative methods. In conclusion, DR-VIDAL uniquely fuses causal assumptions, VAE, Info-GAN, and doubly robustness into a comprehensive, performant framework. Code is available at: https://bitbucket.org/goingdeep2406/dr-vidal/src/master/
Denoising of Motion Artifacts in EEG Signals using DWT-EMD Approach
Authors: Goru Hema Kumar , Ramakrishna B , Panigrahy Damodar
Published: December 2021

Surface Electroencephalography (EEG) is a non-invasive technique used for monitoring and recording the electrical activity of the human brain. Typically, the raw and unprocessed EEG signals are contaminated with various types of physiological artifacts originated from eye blinks and limb moments due to long haul monitoring. The removal of such low frequency motion artifacts in preprocessing techniques could potentially improves the accuracy of diagnosis. In this viewpoint, a multi-resolution analysis such as discrete wavelet transform (DWT) with empirical mode decomposition (EMD) is presented to filter the motion artifacts from the EEG signal. Initially, the low frequency components were separated from EEG signal using DWT decomposition technique and the same are passed to EMD to find intrinsic mode functions (IMFs). Using iterative thresholding algorithm the noisy IMF’s are filtered out, and these denoised approximated components are utilized to reconstruct the motion artifact free EEG signal. The proposed technique shows 15.3218 dB of △SNR, 41.9859% of Relative root mean square error (RRMSE) and the percentage reduction in correlation coefficient (%η) of 65.8213 by using Physionet data base.
Integrative Analysis of Key Genes and Signaling Pathways By Bioinformatics in Patients with Type 1 Diabetes Mellitus Combined with Acute Myocardial Infarction
Authors: Ou Zhenfei , Zhang Xuejuan
Published: December 2021

Although the pathogenesis of type 1 diabetes mellitus (T1D) and acute myocardial infarction (AMI) remains unclear. We investigated the key genes and signaling pathways common to T1D and AMI. First, we screened differentially expressed genes (DEGs) co-expressed by T1D and AMI through gene expression synthesis (GEO) database and text mining. David database was used for enrichment and functional analysis of selected genes. The interaction between proteins (PPI) was created using STRING and Cytoscape software. MCODE is used for module analysis of PPI network. A total of 74 human genes that met the criteria were found in T1D and AMI. The first 10 central genes include STAT3, ITGAM, MMP9, ERBB2, MAPK3, FOS, MYD88, MAPK1, TFRC and TNFRSF1A.The establishment of the aforementioned key genes might serve as novel biomarkers for precision diagnosis and providing medical treatment for the occurrence of AMI in T1D patients in the future.
Speech Recognition In Hearing Aids: Used For Assessing CI Candidacy In Tonal Language Population
Authors: Chang Yu-Lin , Liu Chia-Jou , Chen Pey-Yu , Lin Hung-Ching
Published: December 2021

Objective: CI (cochlear implantation) candidacy is somewhat controversial in severe hearing loss among tonal mandarin-speaking patients. To assess the relationship between pure tone audiometry (PTA) and speech recognition score (SRS), with and without hearing aid amplification, among patients who did not meet the NIH criteria of CI candidacy in tonal language mandarian-speaking countries, especially those with severe hearing loss (70 dB HL < 4FPTA(0.5, 1, 2, 4 KHz) ≤ 90 dB HL) Materials and Methods: A total of 414 patients with sensorineural hearing loss with 774 ears were reviewed retrospectively in a tertiary referral center. The Mandarin Monosyllable Recognition Test (MMRT) was used to evaluate the SRS of these ears. Results: 31% (10/32) of the 32 ears with severe hearing loss, 70-90 dB HL, still showed poor speech recognition (SRS<30%) after hearing aid amplification, while 71% (46/65) of the 65 ears with profound hearing loss, > 90 dB HL, showed poor speech recognition with hearing aid amplification. Conclusions: The speech audiometry with Mandarin Monosyllable Recognition Test (MMRT) helped identify those patients whose 4FPTA< 90 dB HL fell outside the CI candidacy criteria of NIH in tonal language mandarin-speaking countries but showed significantly poor (SRS< 30%) speech recognition performance.
Titanium Dioxide Nanoparticles Mitigated 2,4,6- Trinitrobenzenesulfonic (TNBS) Acid Solution Induced Colitis By Downregulating NF-κB Related Transcription
Authors: Gao Yanjun , Duan Shumin , Lyu Lizhi , Xu Weixing , Ou Xiaxian , Xu Lin , Wang Yun
Published: December 2021

BackgroundTitanium dioxide (TiO2) with nanofractions is increasingly applied in food products as a food additive, which makes consumers under the health risks of titanium dioxide nanoparticles (TiO2-NPs) oral exposure. The recent ban of food additive TiO2 (E171) use in France aggravated public controversy on safety of orally ingesting TiO2-NPs. This work aimed to determine biological effects of TiO2-NPs (38.3 ± 9.3) oral consumption (100 mg/kg bw, 10 days) on TNBS-induced colitis mice and healthy mice, and the additional vitamin E administration was also conducted to explore the possible mechanism of TiO2-NPs on colitis development.ResultsOral consumption of TiO2-NPs exacerbated oxidative stress status in colitis mice by decreasing the colonic glutathione (GSH) and total glutathione (T-GSH) levels, however, TiO2-NPs administration repaired the dysbacteriosis of colitis mice, and downregulated the Toll-like receptors (TLRs), nuclear factor kappa-B (NF-κB) signal pathway and inflammatory factor (IL-1β and TNF-α) transcription levels in colon tissue, which finally decreased the TNF-α expression level and participated in the mitigation of colitis symptoms. Moreover, further vitamin E intervention after TiO2-NPs consumption could relieve the oxidative stress status (mainly by scavenging reactive oxygen species, ROS) and the inflammatory factor over-transcription in colonic epithelium of colitis mice, but the effect of TiO2-NPs on dysbacteriosis repair would not be further changed by Vitamin E. At last, TiO2-NPs induced oxidative stress status and increased NF-κB signal transcription level in colonic epithelium, which increased daily disease activity index (DAI) score and caused mild mucosal inflammatory cell infiltrate in healthy mice. ConclusionOur present work showed that oral TiO2-NPs administration indeed induced oxidative stress and made an adverse effect on the development of colitis, but TiO2-NPs could also downregulate the NF-κB signal transduction level by repairing gut dysbacteriosis, which made a predominant role in alleviating colitis. On the other hand, it should also be noticed that TiO2-NPs oral ingestion caused potential colonic inflammation risks in healthy mice.
Removal of COD in Wastewater By Magnetic Coagulant Prepared From Modified Fly Ash
Authors: Wang Wen , Qi Liqiang , Zhang Pan , Luo Jichen , Li Jingxin
Published: December 2021

In order to investigate the effective method of COD removal from desulfurization wastewater, acid-modified fly ash (AFA) and base-modified fly ash (BFA) were prepared by impregnation method. Then, magnetic coagulants (Fe-AFA, Fe-BFA) were prepared by mixing the modified fly ash with magnetic components. The structural characterization results showed that the specific surface area and the porosity of fly ash were obviously increased after modification. Fe-AFA magnetic coagulant has the best performance and superparamagnetism. Under the same experimental conditions, the maximum COD removal amounts of FA, BFA, AFA, Fe-BFA and Fe-AFA were 2.180, 3.209, 4.631, 3.710 and 5.687 mg/g, respectively. The COD removal amount of Fe-AFA was increased by 112.43% compared with the raw FA. The quasi-second-order kinetic and Langmuir equation could well fit the COD coagulation process of five coagulants. After five cycles, the COD removal amount of Fe-AFA was 2.735 mg/g, and the removal rate still reached 67.53%. These findings provide a feasible method for the treatment of fly ash from coal-fired power plants and the preparation of highly efficient COD trapping magnetic coagulants.
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats
Authors: Chen Siyun , Huang Yushen , Su Hongmei , Zhu Wuchang , Wei Yuanyuan , Long Yan , Shi Yanxia , Wei Jinbin
Published: December 2021

The present study was to investigate the therapeutical effects and mechanisms of Asiatic acid from Potentilla Chinensis against alcoholic hepatitis. Rats were intragastrically fed with alcohol for 12 weeks to induce alcoholic hepatitis and then treated with various drugs for further 12 weeks. The results showed that Asiatic acid significantly alleviated liver injury caused by alcohol in rats, as evidenced by the improved histological changes and the lower levels of AST, ALT, and TBIL. Besides, Asiatic acid significantly enhanced the activity of ADH and ALDH, promoting alcohol metabolism. Asiatic acid suppressed CYP2E1 activity and NADP+/NADPH ratio, resulting in low ROS production. Further study revealed that Asiatic acid markedly reduced hepatocyte apoptosis by regulating the expression levels of the caspase and Bcl-2 families. Moreover, Asiatic acid could regulate the Keap1/Nrf2 and NF-κB signaling pathway, attenuating oxidative stress and inflammation as a result. Interestingly, the comprehensive analysis of transcriptomics and metabolomics indicated that Asiatic acid regulated the gene expression of Gpat4 and thereby affected the biosynthesis of the metabolites (1-acyl-Sn-glycerol-3-phosphocholine, phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine), regulating the glycerophospholipid metabolism pathway and ultimately ameliorating hepatocyte damage. In conclusion, this study demonstrates that Asiatic acid can ameliorate alcoholic hepatitis by modulating the NF-κB and Keap1/Nrf2 signaling pathways and the glycerophospholipid metabolism pathway, which may be developed as a potential medicine for the treatment of alcoholic hepatitis.
Reduced BDNF Expression in Auditory Cortex Contributed to Neonatal Pain Induced Hearing Impairment and Dendritic Pruning Deficiency in Mice
Authors: Li Nanqi , Chen Bing , Jia Gaogan , Xu Rui , Xia Ying , Lai Chuijin , Li Gang , Li Wenxian , Han Yuan
Published: December 2021

Hearing loss in children is common especially in NICU with consequences of worse outcomes in speech, language, education, social functioning, cognitive abilities, and quality of life. Whether neonatal pain is link to increase risks for hearing loss remains to be explored. Here, we implemented Complete Freund's adjuvant (CFA) plantar injection and needle prick model to mimic neonatal pain in NICU during critical period of hearing development. Auditory brainstem response (ABR) test was used to determine the hearing threshold at 4w and 8w postnatal. Sufentanil and Oxycodone were used as analgesic to treat neonatal pain. Hair cell and ribbon synapse stanning were performed to detect cochlear function. Golgi-cox staining and BDNF immunofluorescence of auditory cortex were performed to determine dendritic spine pruning in auditory cortex. The dendritic pruning related protein CaMKII and Rac1/2 level were detected by western blot. We found that CFA induced neonatal pain and ABR threshold increased at 4w and 8w postnatal and the impairment were attenuated after analgesic administration. Neither the inner hair cell (IHC) nor the synapse of CFA mice was damaged in cochlear. CFA mice showed increased dendritic spine density at auditory cortex and reduced BDNF level. Furthermore, Rac1/2 and CaMKII might contributed to the disrupt dendritic spine pruning. Our study suggested that neonatal pain could induced hearing impairment in adulthood ascribed to the reduced BDNF level and AC dendritic spine pruning deficiency, optimal analgesic in early-life could beneficial for hearing development.
Explosive Behaviors on Coupled Fractional-Order System
Authors: Liu Shutong , Sun Zhongkui , Yan Luyao , Zhao Nannan , Xu Wei
Published: December 2021

Fractional derivatives provide a prominent platform for various chemical and physical system with memory and hereditary properties, while most of the previous differential systems used to describe dynamic phenomena including oscillation quenching are integer order. Here, effects of fractional derivative on the transition process from oscillatory state to stationary state are illustrated for the first time on mean-filed coupled oscillators. It is found the fractional derivative could induce the emergence of a first-order discrete transition with hysteresis between oscillatory and stationary state. However, if the fractional derivative is smaller than the critical value, the transition will be invertible. Besides, the theoretical conditions for the steady state are calculated via Lyapunov indirect method which probe that, the backward transition point is unrelated to mean-field density. Our result is a step forward in enlightening the control mechanism of explosive phenomenon, which is of great importance to highlight the function of fractional-order derivative in the emergence of collective behaviors on coupled nonlinear model.