bluuebunny/crossref_metadata_2025 huggingface dataset:
THE NEXUS BETWEEN THEEXTERNAL SECTOR AND INFLATION IN NIGERIA, 1985 -2018
Authors:   Rivers State University, Department of Economics, Port Harcourt, Nigeria., Lenu Kpagih Leera , Leelee N Deekor ,   Ignatius Ajuru University of Education, Department of Economics, Port Harcourt, Nigeria., Nyeche Ezebunwo ,   Rivers State University, Department of Economic, Port Harcourt, Nigeria.
Published: December 2021

The interaction between different economies in the global market could have impact on their key economic variables. Hence, this study set out to examine the impact of the external sector on a key economic variable in Nigeria being Inflation. The study utilized time series data from 1985 to 2018 which was subjected to Augmented Dickey Fuller Test. The next step was to subject the data to an ARDL cointegration test. The result showed that in the short run and long run external sector variables do not have any significant impact on inflation in Nigeria. The paper suggests that money supply and fiscal policy should be used to control inflation in Nigeria.
THE EVALUATION OF THE LEARNING BY CLINICAL REASONING AMONG STUDENTS OF 3RD YEAR OF MEDICINE- FACULTY OF MEDICINE AND PHARMACY OF MARRAKESH
Authors:   Department of Infectious Diseases, Mohammed VI University Hospital, Cadi Ayyad University, Marrakesh, Morocco., Ihbibane F. , Adermouch L. ,   Department of community medicine and epidemiology, Mohammed VI University Hospital, Cadi Ayyad University, Marrakesh, Morocco., Amine M. ,   Department of community medicine and epidemiology, Mohammed VI University Hospital, Cadi Ayyad University, Marrakesh, Morocco., Tassi N. ,   Department of Infectious Diseases, Mohammed VI University Hospital, Cadi Ayyad University, Marrakesh, Morocco.
Published: December 2021

Clinical reasoning learning (CRA) is a teaching method based on interactive teaching. Its objective is to lead the student to acquire a diagnostic approach by developing a clinical reasoning. In order to evaluate this method of active teaching from the point of view of the medical student, we carried out a cross-sectional descriptive study among students of the 3rd year of medicine of the faculty of medicine and pharmacy of Marrakesh, having held out-patient clinics at the Mohamed VI university hospital in Marrakesh or at Ibn Sina Military Hospital and attended at least two CRA sessions during their day school curriculum. Data were collected during the last week of July 2016, via a quiz. One hundred and forty-two quiz were operated with a participation rate of 95%. Students reported that CRA sessions are interesting but insufficient. The CRA sessions had a very important place in medical education for 84% of our students and they had brought medical knowledge to the majority. The clinical reasoning learning made it possible to apply the theoretical knowledge acquired during the medical studies for 62% students and allowed to acquire medical skills for 95%. It turns out that the CRA is a teaching method which is appreciated by students and which is an interesting complement to the traditional forms of teaching.
FACTORES DE RIESGO ASOCIADOS A RECIDIVA EN PACIENTES CON ANTECEDENTE DE PLASTIA DE HERNIA INCISIONAL EN CENTRO MEDICO NAVAL
Authors:   Departamento De Cirugia General, Centro Medico Naval, Ciudad De Mexico, Mexico., Diaz-Gonzalez D. Alejandro , Francisco Chaga-Torres Jose ,   Departamento De Cirugia General, Centro Medico Naval, Ciudad De Mexico, Mexico.
Published: December 2021

Incisional hernia repairisone of themostfrequentsurgicalprocedures in General Surgerydue to thehighprevalence of thispathology Thesurgicaltechniqueinvolvesthe use ornot of prostheticmesh, depending onthesurgeon, however, anothercommonproblemistherecurrence of the hernia after a plasty, due to multiplefactorsthatwerestudied in thisresearch, beingnecessary to haveknownthefollow-up of thesepatients in theirpostoperativeperiod and whatcommoncharacteristicstheypresentedthatconditionedthepatients to presentthesepostoperativecomplications and evensurgicalreoperations. Itiswidelydemonstratedthattherecurrence of incisional hernia plastyis a conditionthat can be prevented, knowingtheconditioningriskfactors. Itisimperative to knowtheway in whichpatientshavebeenapproached, theirfollow-up and theirtherapy, determine whichriskfactorswererelevantaccording to thepathology to be studied and thusproposeanalternativesolution, thusreducingmorbidity and mortality. In ourpatients, thesurgicalreoperationsthatnotonlyaffectthequality of life of thepatientsbutalsothegreaterconsumption of material and economicresources in theInstitution. Objective: to determine themostfrequentriskfactorsassociatedwithrecurrence in patientswith a history of incisional hernia plasty at the Naval Medical Center. Material And Methods: 48 electronic records of patientswith a history of abdominal wall hernia plastywereanalyzed. Descriptive and inferentialanalysiswascarriedout in order to associateriskfactorswithrecurrence of incisional hernia. Results: No statisticallysignificantresultswerefoundfortheassociation of obesity, surgicalsiteinfection and smoking withrecurrence of incisional hernia. However, in oursampleobesitywaspresent in 54% of thepatients and 25% overweight. Conclusions: In Naval Medical Center, therate of patientswithincisional hernia plastyislimited, however, overweight andobesityis a characteristicthatourpopulationpresents in common and thatclearly determines multiplecomplications, such as recurrence in this case, requiring a narrowapproach to thiscondition.
TO DEVELOP A SET OF RECOMMENDATIONS FOR PARENTS WHOSE CHILDREN ARE IN THE EARLY ADOLESCENT AGE GROUP
Authors:   Research Scholar, Department of Home Science Faculty of Social Science and Humanities Bhupal Nobels University, Udaipur (Raj.)., Mehta Shreya , Babel Garima ,   Associate Professor, Department of Home Science Faculty of Social Science and Humanities Bhupal Nobels University, Udaipur (Raj.).
Published: December 2021

The present study was undertaken to assess the parenting styles of mother and father of early adolescent and its influence on personality development. The investigation took place in the municipal boundaries of Udaipur city. The total sample of the research consisted of 360 respondents who belonged to middle income group. The sample selected comprised of early adolescents (120) in the age range of 11-13 years and their father (120) and mother (120). Few recommendations for parents of early adolescent were developed which can be useful for further researches.
Government expenditure and macroeconomic stability conundrum in Zimbabwe
Authors: Maduku Harris , Tavonga Mazorodze Brian
Published: December 2021

The objective of this paper was to explore the effect of government expenditure growth on macroeconomic stability in Zimbabwe. Public expenditure has grown over time but as per a priori expectations, other macroeconomic variables have not been forth coming. What the country has actually experienced is prolonged macroeconomic instability. The paper contributes to the body of literature in two ways, (1) by creating a macroeconomic instability index and (2) by being the first in the Zimbabwean context to explore this conundrum. To achieve the main objective of the paper, the study used a cointegrated vector error correction model (VECM) and Granger causality with data spanning 1981 to 2019. The study did not find a statistically significant relationship between government expenditure and macroeconomic stability as argued mostly by the Keynesians. However, according to a priori expectations, the relationship turned out to be rightly negative. To buttress the Cointegrated-VECM results, granger causality tests were also conducted where no causality was found from government spending to macroeconomic stability, and vice versa (causality running from instability to government spending). This paper recommends that, Zimbabwe’s policy makers may need to consider proactive government spending or policies, since that helps the economy to successfully avoid possible risks such as macroeconomic instability. When policies are proactive rather than reactive, that helps by seizing untapped opportunities, and the economy justly avoids consequences of reactive governance.
Employee motivation and job satisfaction in family-owned businesses
Authors: Mura Ladislav , Hajduova Zuzana , Smorada Marián , Jakubova Zuzana
Published: December 2021

This study aimed to investigate the differences in motivational focus and sources of satisfaction between family and non-family employees in family businesses. Data from a questionnaire survey conducted between May and September 2021 were used to examine the relationship of work motivation between family and non-family employees. Data were collected via a questionnaire and interviews with 56 non-family employees and 148 family employees from family businesses of eight Slovak regions. To meet the stated aim, relevant quantitative methods such as the two-sample Fisher’s F-test, two-sample Student’s t-test with inequality of variances, and the Pearson correlation method were applied. Based on the established results, it can be assumed that it is possible to adapt the dealings with the employees of family companies more closely to their individual needs, and thus contribute to their performance. Non-family employees are more oriented towards economic benefits. Family employees show a more balanced orientation between economic benefits and moral satisfaction. This confirms that financial considerations are still an important factor of motivation for non-family employees. According to the results of the study, non-family employees tend to focus on content and activity, while family employees rather focus on success. A possible explanation could be that family members perceive the success of a company more than their own and feel more confident in the choice of activities they would like to carry out, so they take this fact more than for granted.
AcknowledgmentThis paper has been supported by funds of the project VEGA No. 1/0240/20. This study was supported by the project GAAA 5-5/2020 “Development of family businesses in Slovak regions”, which has received funding from Grant Agency Academia Aurea and by project VEGA 1/0813/19 “Managing the development of innovative and start-up forms of businesses in international environment and verification of INMARK concept”, which has received funding from the Ministry of Education, Science, Research and Sport of the Slovak Republic.
Dynamic Panel Surveillance of COVID-19 Transmission in the United States to Inform Health Policy: Observational Statistical Study – A Critical Review of Article
Authors: Sibanda Nhlonipho Precious Sithole
Published: December 2021

This is a critical appraisal of a manuscript outlining additional indicators used in the United States to augment traditional disease surveillance tools. The article went through the peer-review process. Therefore, it may be considered as objective and unbiased. The structure of the article is coherent, and it was published in a journal for digital medicine, health, and health care in the internet age. The article has contributed to the literature and provides a basis for strengthening existing surveillance systems to improve public health outcomes. However, it is suggested that whenever new indicators are being developed, their essential components must be fully defined.
Analysis of the vehicle: applying finite element method of 3D data
Authors: Ozcan Ferhat , Ersoy Sezgin
Published: December 2021

Systems that allow engineering studies to be done in a virtual environment with computer software, to test designs in a virtual environment and to carry out design verification studies are developing day by day. The Finite Element Method (FEM) is a method used to simulate structurally with strength visualizations, production and weight determination, proper management of materials and costs, and numerically predict how a part or assembly behaves under certain conditions with Finite Element Analysis (FEA). In this paper, control of connection elements, material and mesh (solid, surface and volume) controls and preliminary analysis processes were carried out after transferring a 3D data with defined material and connection elements to Ls-DYNA program to perform Finite Element Analysis. As a result of the preliminary analysis, the crash test of the car with the wall was carried out with the Ls-DYNA program of the model, which is suitable for Finite Element analysis. The results of the crash test were interpreted in the Ls-DYNA program. In this study, it is aimed to understand the results according to time, car displacement and speed as a result of the collusion of the car with the wall.
Tohum Kaplamasında Kullanılan Bazı Pestisitlerin Mısırın Morfolojik Ve Kalite Özelliklerine Etkileri
Authors: KOCA Onur , YALÇIN Melis , TURGUT Cafer
Published: December 2021

Bu çalışma ile metalaxy-M + fludioxonil (Maxim XL 035 FS), clothianidin (Poncho FS 600)
ve cyantraniliprole (Fortenza 600 FS) etken maddeli tohum ilacı olarak kullanılan pestisitleri mısırın
(Zea mays L.) verim ve kalitesi üzerine etkileri belirlenmiştir. Belirtilen pestisitlerin önerilen dozları
kullanılarak Pioneer P2088 mısır çeşidinin tohumlarına kaplama işlemi gerçekleştirilmiştir.
Çalışmada, mısır çeşidinin birçok morfolojik özelliklerine (tohum verimi, bitki boyu, koçan boyu,
koçanda tane sayısı, koçandaki tohum ağırlığı, bin tohum ağırlığı, sap kalınlığı ve yaprak kalınlığı) ek
olarak bazı tohum kalite parametreleride (kül, yağ, protein ve nişasta oranları) ölçülmüştür.
Çalışmanın sonucunda, yaprak kalınlığı dışında ölçülen tüm morfolojik özelliklerde uygulamalar
arasındaki farklılıkların önemsiz olduğu bulunmuştur. Buna karşın çalışmada ölçülen tüm kalite
özelliklerinde uygulamalar arasındaki farklılıkların önemli olduğu tespit edilmiştir. En yüksek yaprak
kalınlığı (5.04 mm) ve nişasta oranı (% 58.61) değerleri metalaxyl-M + fludioxonil uygulamasından
elde edilmiştir. En yüksek kül (% 1.22) ve protein içeriği (% 8.71) kontrolden elde edilmiştir.
Tohumlarda en yüksek yağ (% 4.20) oranı clothianidin uygulamasında ölçülmüştür.
Fusarium Başak Yanıklığının Buğday Kalite Parametreleri Üzerine Etkisi: Enfekteli Başaklara Fungisit Uygulamaları Sonrasındaki Değişim
Authors: KÖYCÜ Nagehan Desen
Published: December 2021

Fusarium culmorum’un (Wm. G. Sm.) Sacc. tahıllarda fide yanıklığı (FSB), kök çürüklüğü ve başak
yanıklığına (FHB) neden olduğu enfeksiyonlar, dünyada ve aynı zamanda Trakya Bölgesi’nde de önemli bir
sorundur. Bu çalışmanın amacı, F. culmorum’un buğday tanelerinde protein oranı (%), tanecik boyutu (Particul
Size Index), Zeleny sedimantasyon (ml), gluten (%) ve gluten index (%) kriterlerinin kalite parametreleri üzerine
etkisini ve fungus ile enfekteli başaklara fungisit uygulamaları sonrasında tane kalite kriterlerindeki değişimi
belirlemektir. Buğdayın antezis döneminde (ZGS 61), başaklara el spreyi ile fungusun spor süspansiyonu
uygulaması yapılmıştır. Başaklara fungusun suni inokulasyonundan 48 saat sonra,
prothioconazole+trifloxystrobin (Madison SC, Bayer CropScience, Türkiye), thiophanate-methyl+tetraconazole
(Yamato SE, SumiAgro, Türkiye) ve tebuconazole (Rally SC 250, Agrofarm, Türkiye) etkili maddeleri el
pulverizatörü ile uygulanmıştır. Deneme sonunda buğday tanelerinin kalite parametrelerindeki değişimi tespit
edilmiştir. Fungisit uygulaması yapılan enfekteli başaklarla karşılaştırıldığında, FHB ile enfekteli tanelerde de
protein oranı içeriği değişmemiştir. Enfekteli tanelerde yaş gluten (%), tanecik boyutu (PSI), Zeleny
sedimantasyon miktarı (ml) ve gluten indeks (%) değerleri kontrolle kıyaslandığında azalmıştır. Fungisitler
arasında, prothioconazole+trifloxystrobin kalite parametreleri üzerinde en etkili fungisit olmuştur. Zeleny
sedimantasyon ve yaş gluten arasındaki korelasyon pozitif ve önemli (p<0.01) bulunmuştur.
Biyotik Stres Koşullarına Dayanıklı Turp Islah Programında Kullanılan Genitörler
Authors: PALA Kübra , KARAAĞAÇ Onur , BALKAYA Ahmet
Published: December 2021

Turp (Raphanus sativus L.), Brassicaceae (Lahanagiller) familyasının içinde yer alan önemli bir sebzedir.
Lahanagil grubu sebze türleri içerisinde kültüre alınan en eski türdür. Turplar şekil ve irilik özellikleri yönünden çok geniş bir genetik vasyasyona sahiptir. Günümüzde turp yetiştiriciliğinde biyotik stres (hastalık ve zararlı etmenleri vb.) faktörleri nedeniyle önemli düzeylerde verim ve kalite kayıpları meydana gelmektedir. Turp yetiştiriciliğinde en yaygın olarak gözlemlenen hastalıklar; beyaz pas, Fusarium solgunluğu, mildiyö ve şalgam mozaik virüsü olarak sıralanabilir. Ayrıca turplar; kök, gövde ve yaprakları ile beslenen lahana kurdu, turp afiti, kök lezyon nematodu gibi birçok zararlının da tehlikesi ve tehdidi altındadır. Genetik kaynaklar, çeşit ıslah çalışmalarının başarıya ulaşmasında en önemli faktörlerden birisi olan fenotipik varyasyonun temelini oluşturmaktadır. Ayrıca halihazırda ticareti yapılan turp çeşitlerinde bulunmayan dayanıklılık genleri, yabani ve farklı alt varyetelerde bulunabilmektedir. Son yıllarda turp bitkisinde mevcut genetik
kaynaklardan yararlanılarak hibrit çeşit ıslahı çalışmalarında hastalık ve zararlılara karşı tolerant yeni genotiplerin geliştirilmesi ve tolerantlıkta rol alan mekanizmaların belirlenmesine yönelik çalışmalara daha fazla önem verilmeye başlanmıştır. Bu derlemede turp ıslah programlarında dayanıklılık kaynağı olarak yararlanılan genitörler ve hastalık ve zararlılara karşı tolerant yeni genotiplerin geliştirilmesi konusunda yapılan ıslah çalışmaları derlenmiştir.
Capsicum chinense Türüne Ait Biber Genotiplerinde Sıcaklığın Tohum Çimlenmesi Üzerine Etkisi
Authors: GÖKPINAR Bircan , BALKAYA Ahmet , ŞAHİN Güldane Tuğba
Published: December 2021

Bitkisel üretimde tohum çimlenmesi ve çıkış için gerekli olan optimum sıcaklık değerleri, bitki tür ya da çeşitlerine göre farklıklar göstermektedir. Sıcaklık, çimlenme ve çıkış sürecini etkileyen önemli bir çevresel faktördür. Capsicum chinense biber türü; tohum canlılığı, tohum iriliği, tohum şekli, tohum rengi yönünden yüksek düzeyde varyasyon göstermektedir. Bu çalışmada, C. chinense türüne ait biber tohumlarında sıcaklık faktörünün çimlenme kapasiteleri üzerine olan etkileri incelenmiştir. Araştırmada; C. chinense türüne ait 10 biber genotipinin tohumlarının çimlenme performansları, 11 farklı sıcaklık uygulamasında (9 °C, 12 °C, 15 °C, 18 °C, 21 °C, 24 °C, 27 °C, 30 °C, 33 °C, 36 °C, 39 °C) belirlenmiştir. Araştırma sonucunda; 9 °C ve 15 °C arasında çimlenmenin olmadığı, 21 °C ve 33 °C sıcaklık aralıklarında ise çimlenme hızı ve çimlenme oranlarının yükselen sıcaklıklara bağlı olarak artışlar gösterdiği saptanmıştır. Biber genotiplerinde, 24 °C ve 27 °C sıcaklık uygulamalarında en yüksek çimlenme oranlarına ulaşılmıştır. Çimlenme oranı değerleri yönünden CC-51 ve CC-63 genotiplerinin diğer genotiplere göre daha yüksek olduğu belirlenmiştir. Ayrıca tohumların çimlenmesi üzerine, sıcaklık esas alınarak geliştirilen matematiksel modelleme ile, çimlenme oranın tahmin edilmesi olanağı da araştırılmıştır. Bu amaçla; çimlenme potansiyellerinin tahmini için Uzun ve ark. (2001) tarafından önceden türetilmiş model tarafımızdan geliştirilerek [D= a+(b x T) +(c x T2)] şeklinde kullanılmıştır. Her bir genotip için üretilen denklemlerin regresyon katsayılarının (R2), çimlenme oranı değerleri için 0.33 ile 0.95 arasında değiştiği belirlenmiştir. Çimlenme performans özellikleri yönünden öne çıkan C. chinense genotiplerinin gelecekte biber ıslah programında değerlendirilmesi planlanmaktadır.
The devil is in the details: emerging insights on the relevance of wastewater surveillance for SARS-CoV-2 to public health
Authors: Hrudey Steve E. , Conant Bernadette
Published: December 2021

The severe health consequences and global spread of the COVID-19 pandemic have necessitated the rapid development of surveillance programs to inform public health responses. Efforts to support surveillance capacity have included an unprecedented global research response into the use of genetic signals of SARS-CoV-2 in wastewater following the initial demonstration of the virus' detectability in wastewater in early 2020. The confirmation of fecal shedding of SARS-CoV-2 from asymptomatic, infected and recovering individuals further supports the potential for wastewater analysis to augment public health conventional surveillance techniques based on clinical testing of symptomatic individuals. We have reviewed possible capabilities projected for wastewater surveillance to support pandemic management, including independent, objective and cost-effective data generation that complements and addresses attendant limitations of clinical surveillance, early detection (i.e., prior to clinical reporting) of infection, estimation of disease prevalence, tracking of trends as possible indicators of success or failure of public health measures (mask mandates, lockdowns, vaccination, etc.), informing and engaging the public about pandemic trends, an application within sewer networks to identify infection hotspots, monitoring for presence or changes in infections from institutions (e.g., long-term care facilities, prisons, educational institutions and vulnerable industrial plants) and tracking of appearance/progression of viral variants of concern.
GC/MS screening of buckthorn phytochemicals and their use to synthesize ZnO nanoparticles for photocatalytic degradation of malachite green dye in water
Authors: Hasan Ibrahem M. A. , Tawfik Ahmed R. , Assaf Fawzy H.
Published: December 2021

Zinc oxide nanoparticles (ZnO NPs) were biosynthesized. According to gas chromatography/mass spectrometry analysis, chalcone, the main phytochemical, is probably complexed with Zn ions that are then oxidized to ZnO NPs by atmospheric O2 during heating. The ZnO NPs were characterized by thermogravimetric analysis, Fourier transform infrared spectroscopy, X-ray diffraction, field emission scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and Brunauer–Emmett–Teller surface area analysis. Sphere-like ZnO NPs were formed with 11 nm mean crystallite size, 5.2 m2 g−1 surface area, and 0.02 cm3 g−1 total pore volume. The synthesized ZnO showed excellent photocatalytic degradation (96.5±0.24% in 1 hour at 25 °C) of malachite green (MG) in aqueous solutions under ultraviolet light at optimum conditions; pH 10, MG initial concentration of 20 mg L−1, and ZnO dose of 1.5 g L−1. Also, ZnO showed very good reusability (92.9± 0.2% after five runs). The experimental data obeyed pseudo-first-order kinetics (R2 = 0.92). The photocatalysis process was dependent on the following species in the order: OH. > electron/positive hole pairs > O2.−. Moreover, photodegradation efficiency decreased in the presence of CO32−, HCO3−, and Cl−, but increased in the presence of NO3− and SO42− ions. Thus, the green synthesized ZnO NPs can be applied as an efficient photocatalyst for the removal of MG from aqueous media.
O movimento “#ELENÃO” e seu apagamento discursivo sob a contranarrativa do “#ELESIM”
Authors: Silva Jamile
Published: December 2021

RESUMO: Entendendo a língua como um construto de significados e significantes, e que produções discursivas são uma forma de construir narrativas através da produção de sujeitos, ideologicamente interpelados; adentramos à cena político-discursiva das eleições de 2018 com o intuito de proceder a uma investigação, à luz da Análise do Discurso de linha francesa, sobre a construção do contradiscurso que aviltou o êxito da maior manifestação social liderada por mulheres da história do Brasil. Metodologicamente, partimos da análise de enunciados retirados da rede social Facebook, onde ocorreu a maior concentração de apoio a essas narrativas. Com isso, pretendemos estabelecer a correlação entre os discursos antagônicos que culminaram no desfecho das manifestações de 2018, demonstrando, assim, como se deu o processo de (re) significação que reavivou condutas discriminatórias, as quais, até então, pensava-se estarem obsoletas, mas foram reintroduzidas no coletivo nacional. Para tanto, no que diz respeito à construção dos sentidos, memória e sujeito, reportamo-nos a Pêcheux (2010), com reflexões em Courtine (2006), Brandão (2004) e Grigoletto (2005). A partir das análises e verificações, percebe-se a influência ideológica que os arranjos enunciativos exercem sobre as práticas e escolhas discursivas dos sujeitos.

 

PALAVRAS-CHAVE: Análise do Discurso (AD); movimento #EleNão; sujeito; contradiscurso.
Análise de iconicidade das variantes do termo coronavírus em língua brasileira de sinais – LIBRAS
Authors: Abreu Walber , Brito Higor , Souza Renne
Published: December 2021

Atualmente, por conta dos avanços da COVID-19 pelo mundo surgiu a necessidade de as pessoasconsumirem mais informações e se comunicarem de maneira remota. Além disso, houve anecessidade da criação de um léxico técnico pelos sinalizantes de línguas de sinais para suprir asnecessidades de comunicação nesse novo cenário. Dessa forma, o presente artigo visa analisar aformação icônica dos sinais referentes ao termo “coronavírus” na Língua Brasileira de Sinais –Libras, nos níveis fonológico e morfológico, através de análises dos aspectos estruturais dos sinaise da descrição desse léxico sob a luz do modelo proposto por Taub (2004). A presente pesquisa sesitua no nível exploratório e se caracteriza como do tipo pesquisa básica. Foram selecionados 3vídeos de redes sociais que apresentavam, cada um, uma variante do sinal de CORONAVÍRUS,essas variantes foram analisadas qualitativamente. Como resultados, temos que (i) o processo decriação desses sinais revela motivações relacionadas a origem da doença, a estrutura do vírus e aocontágio e sintomas da doença e; (ii) a estrutura fonológica das variantes revela o importante papelda configuração de mão e do movimento na constituição dos sinais. Com isso, concluímos que emléxicos emergentes a iconicidade tem um papel fundamental na constituição dos termos, esse fatornão rebaixa as línguas de sinais ao status de línguas não naturais, mas sim, demonstra umapeculiaridade dessas línguas, que é a iconicidade. Mostrando assim, a riqueza das línguas demodalidade visual-gestual.
“É como perder uma biblioteca que ensinava a todos”: biopoder, bio(necro)política e população indígena na Amazônia brasileira em discursos sobre a pandemia da covid-19
Authors: Fonseca Araújo Israel , Vieira da Silva Francisco
Published: December 2021

Este trabalha focaliza a pandemia de Covid-19, quando discursivizada pela mídia virtual, no que concerne às estratégias (bio)políticas e/ou necropolíticas emanadas da governança nacional em relação aos povos originários (indígenas) amazônicos, assim como a ribeirinhos e demais populações inseridas nesses territórios. A partir do esforço em articular as perspectivas teóricas de Michel Foucault (2005; 2009; 2012) acerca do biopoder, da biopolítica e da governamentalidade, e a necropolítica com as teorizações de Achille Mbembe (2016), analisamos um conjunto de seis publicações da mídia virtual, com vistas a perscrutar o modo de funcionamento de estratégias políticas de governamento da população que dão a conhecer as relações de poder-saber direcionadas a esses sujeitos da Amazônia brasileira. Sobre a metodologia, convém frisar que se trata de um estudo descritivo-interpretativo, de abordagem qualitativa. Pontuam-se que as táticas biopolíticas empreendidas em mira dos povos indígenas se efetivam enquanto uma questão de “racismo de Estado”, de assunção da vida pelo poder estatal, dispositivo que se assemelha a uma tática de guerra.
A modalidade volitiva no discurso de autoajuda religioso do padre Reginaldo Manzotti
Authors: Oliveira André Silva
Published: December 2021

Este trabalho tem por objetivo descrever e analisar o condicionamento dos aspectos pragmáticos sobre os aspectos semânticos na instauração da modalidade volitiva no discurso de autoajuda religioso. Para isso, tomamos por base a perspectiva do funcionalismo linguístico que trabalha com o uso efetivo da língua e a integração da pragmática na descrição dos fenômenos linguísticos. Desse modo, selecionamos quatro obras do Padre Reginaldo Manzotti inseridas no domínio do discurso de autoajuda religioso: Batalha espiritual: entre anjos e demônios (2017), Combate espiritual: no dia a dia (2018), O Poder Oculto (2019) e As muralhas vão cair: como fazer um Cerco de Jericó em sua vida (2020). Após a análise das obras, verificamos que o grau de comprometimento do falante no que tange à expressão de volição (extremo, alto, médio, baixo e muito baixo) condiciona tanto os valores modais volitivos (desideração, optação, intenção, exortação e nolição) quanto a natureza do enunciado modalizado (disposicional, reportativa, expressiva e apreciativa).
PALAVRAS-CHAVES: Modalidade; Volitividade; Discurso de Autoajuda.
Continuum categorial entre explicação e restrição: uma análise de orações relativas
Authors: Bispo Edvaldo Balduino , Fonseca Lopes Anielle Bruna
Published: December 2021

Neste artigo, analisamos orações relativas à luz de um continuum categorial entre a explicação e restrição. Objetivamos correlacionar propriedades formais e semântico-pragmáticas dos SN antecedentes ao tipo de relativa que a eles se vincula e propor a distribuição das orações analisadas de forma gradiente. A pesquisa tem abordagem quali-quantitativa e caráter descritivo-explicativo; sustenta-se teoricamente na vertente norte-americana da Linguística Funcional (GIVÓN, 1995; MARTELOTTA, 2011; FURTADO DA CUNHA; BISPO, 2013). Os resultados indicam que orações restritivas ocorrem em maior quantidade com antecedentes novos e menos definidos, enquanto as explicativas, mais frequentemente, ligam-se a SN disponíveis e com maior grau de definitude. Antecedentes evocados e inferíveis ocorrem com ambos os tipos de relativas, assim como aqueles com grau intermediário de definitude. Esses achados revelam que esses dois grupos de relativas não representam categorias discretas, mas abarcam um conjunto de orações que se distribuem numa escala categorial em cujos extremos situam-se as explicativas típicas, com menor grau de integração à oração matriz e a ela relacionadas por adjunção/hipotaxe, e as restritivas prototípicas, com maior aderência morfossintática à matriz e a ela articuladas por encaixamento/subordinação.
Wkład doktryn religijnych w kształtowanie postaw pro-środowiskowych
Authors: Sadowski Ryszard F.
Published: December 2021

Strzeszczenie nie jest dostępne
Potrzeba rozumienia i aktualizacji pojęcia godności osoby ludzkiej wobec współczesnych zagrożeń związanych z ludzkim życiem
Authors: Smoderek Karolina
Published: December 2021

Właściwe rozumienie godności osoby w obliczu wyzwań współczesnej medycyny staje się dziś tematem naglącym. W obecnym porządku prawnym promuje się tę wartość jako podstawę nowoczesnego społeczeństwa, w którym jest miejsce na wolność, równość oraz szacunek przysługujący każdej jednostce ludzkiej. Potwierdzają to dokumenty o międzynarodowej randze, jak również szereg praw nadanych człowiekowi dla jego ochrony. Pojęcie godności znalazło należne sobie miejsce stając się podstawą praw pacjenta. Jednak zapisy prawne nie gwarantują obecnie, jak należało by się spodziewać, należytej ochrony w sytuacjach zagrożenia zdrowia i życia ludzkiego. Trudno doszukać się w nich klarownego odwołania do kryterium godności rozumianego w sposób jednoznaczny. Pomimo, że odwołanie się do godności stanowi akceptowaną formę uzasadnienia w bioetyce, to w dynamicznie rozwijającym się obszarze biomedycyny łatwo stracić ją z pola widzenia. Stąd istnieje potrzeba właściwego rozumienia i aktualizacji pojęcia godności, aby nie wyczerpywała się jedynie w katach prawnych, jako pusta formuła.
Kwestionariusz Zaawansowania W Uważności (polska adaptacja i walidacja)
Authors: Radoń Stanisław
Published: December 2021

Celem artykułu była polska adaptacja kwestionariusza MINDSENS, służącego do pomiaru zaawansowania w uważności oraz innych technik opartych na medytacji. Próbę badawczą stanowiły dwie grupy osób: 1) z doświadczeniem w medytacji (N = 656, tj. 74,6%, w tym medytacja chrześcijańska – 33,5%; uważność – 24,4%; techniki koncentracyjne, m.in. joga i medytacja transcendentalna – 16,2%) oraz 2) bez doświadczenia medytacyjnego (N = 226, tj. 25,4%), kontrolowane pod względem długości i częstotliwości praktykowania oraz zaburzeń. Przeprowadzona procedura walidacyjna wykazała, że polska adaptacja MINDSENS, tj. Kwestionariusz zaawansowania w uważności (Obserwowanie, Niereaktywność i Decentracja) charakteryzuje się dobrymi właściwościami psychometrycznymi pod względem rzetelności łącznej (0,74 ≤ CR ≤ 0,93) i zbieżnej (0,82 ≤ H ≤ 0,93), stabilności bezwzględnej (0,76 ≤ rtt ≤ 0,82), trafności wewnętrznej (model 3-czynnikowy z bifaktorem) oraz zewnętrznej. Kwestionariusz ten może więc być użytecznym narzędziem służącym do pomiaru zaawansowania w uważności w stosunku do osób z doświadczeniem medytacyjnym, a pochodzących zarówno z populacji klinicznych, jak i pozaklinicznych, w wieku od 15 do 72 lat.
Osobowościowe uwarunkowania ryzyka wypadków drogowych u kierowców – przegląd wybranych badań i propozycja ich interpretacji w ramach Kołowego Modelu Metacech Osobowości
Authors: Gasiul Henryk , Strus Włodzimierz
Published: December 2021

Celem artykułu jest przegląd badań nad osobowościowymi uwarunkowaniami zachowań ryzykownych, podatności na zmęczenie oraz wypadkowości w ruchu drogowym, a dalej próba ujęcia tych uwarunkowań w ramach Kołowego Modelu Metacech Osobowości (KMMO). Dotychczasowe badania oraz różnorodność stosowanych w nich modeli teoretycznych i narzędzi pomiaru sprawiają istotne trudności w integracji zgromadzonych danych empirycznych. Wydawało się, że Pięcioczynnikowy Model Osobowości, zwany też modelem Wielkiej Piątki, mógł spełniać taką funkcję syntetyzującą, jednak najnowsze badania i analizy wskazują na ograniczony potencjał integracyjny i teoretyczny tego modelu, szczególnie w porównaniu z modelami uwzględniającymi tzw. czynniki wyższego rzędu lub metacechy osobowości. Jednym z takich modeli jest właśnie KMMO, stąd też autorzy artykułu proponują uwzględnienie go jako modelu integrującego dotychczasowe zróżnicowane wyniki badań empirycznych nad osobowościowymi uwarunkowaniami zachowań ryzykownych, zmęczenia oraz wypadkowości w ruchu drogowym. Przedstawione w artykule analizy wykazały, że w tym kontekście istotne są 3 metacechy: Delta-minus/ Poszukiwanie wrażeń, Alfa-minus/Rozhamowanie i Gamma-minus/Dysharmonia, a model predykcyjny oparty na tych szerokich zmiennych osobowościowych jest wartościowy w sensie oszczędności i trafności.
Epigenetic Modulators as Treatment Alternative to Diverse Types of
Cancer
Authors: Gutiérrez Jorseth Rodelo , Salgado Arturo René Mendoza , Arias Marcio De Ávila , San-Juan-Vergara Homero , Rada Wendy Rosales , Gómez Carlos Mario Meléndez
Published: December 2021

DNA is packaged in an octamer of histones, forming chromatin, a complex of
DNA and proteins. The structural matrix of a chromosome, chromatin and its changes are
now regarded as important factors in controlling gene expression, which has sparked a lot
of interest in understanding genetic pathways governing various diseases, including cancer.
DNA methylation in the CpG dinucleotide as a transcriptional silencing mechanism,
post-translational histone modifications such as acetylation, methylation, and others that
affect chromatin structure, ATP-dependent chromatin remodelling, and miRNA-mediated
gene silencing are all found to be important in various types of cancer. In this review, we
analyze the main alterations in gene expression, epigenetic modification patterns in cancer
cells, the main modulators and inhibitors of each epigenetic mechanism, and the molecular
evolution of the most representative inhibitors, all of which point to a promising future
for HAT, HDAC, non-glycoside DNMT inhibitors, and domain inhibitors.
Remdesivir: Mechanism of Metabolic Conversion from Prodrug to Drug
Authors: Kapoor Saumya , Dubey Gurudutt , Khatun Samima , Bharatam Prasad V.
Published: December 2021

Background:

Remdesivir (GS-5734) has emerged as a promising drug during the challenging times of
COVID-19 pandemic. Being a prodrug, it undergoes several metabolic reactions before converting to its active
triphosphate metabolite. It is important to establish the atomic level details and explore the energy profile of the
prodrug to drug conversion process.

Methods:

In this work, Density Functional Theory (DFT) calculations were performed to explore the entire metabolic
path. Further, the potential energy surface (PES) diagram for the conversion of prodrug remdesivir to its active
metabolite was established. The role of catalytic triad of Hint1 phosphoramidase enzyme in P-N bond hydrolysis was
also studied on a model system using combined molecular docking and quantum mechanics approach.

Results:

The overall energy of reaction is 11.47 kcal/mol exergonic and the reaction proceeds through many steps
requiring high activation energies. In the absence of a catalyst, the P-N bond breaking step requires 41.78 kcal/mol,
which is reduced to 14.26 kcal/mol in a catalytic environment.

Conclusion:

The metabolic pathways of model system of remdesivir (MSR) were explored completely and potential
energy surface diagrams at two levels of theory, B3LYP/6-311++G(d, p) and B3LYP/6-31+G(d), were established
and compared. The results highlight the importance of an additional water molecule in the metabolic reaction. The PN
bond cleavage step of the metabolic process requires the presence of an enzymatic environment.
MicroRNAs: Beyond Post-transcriptional Regulation of mRNAs
Authors: Viridiana Cervantes-Ayala Andrea , Ángel Velázquez-Flores Miguel , Ruth Ruiz Esparza-Garrido
Published: December 2021

MicroRNAs (miRNAs), small non-coding RNAs, participate in the transcriptional and post-transcriptional regulation of eukaryotic genes, and are potential biomarkers for diseases. Mature miRNAs can be located in both the nucleus and cytoplasm, where they perform their regulatory function. The discovery of new miRNAs and the identification of their targets and functions are fundamental to understanding the biological processes regulated by them, as well as the role they play in diseases. This present study researched miRNAs function at nuclear level and as circulating molecules.
Association between oral nutritional supplementation and clinical and nutritional outcomes in the management of hospital malnutrition
Authors: Ferreira dos Santos Ayla Nauane , Silva Kamila Luana do Nascimento , Santos Vinícius Eponina dos , Santos Ranna Adrielle Lima , Rocha Vivianne de Sousa
Published: December 2021

Objective: To evaluate the association between oral nutritional supplementation and clinical and nutritional outcomes in the management of hospital malnutrition. Methods: This is a longitudinal observational study conducted by collecting electronic medical records of patients admitted to a university hospital between 2019 and 2020. Malnourished adult and elderly patients, who have been eating exclusively orally and using a nutritional supplement, were included.Sociodemographic, clinical, biochemical, nutritional risk, nutritional assessment, acceptance of nutritional prescription and characteristics of the nutritional supplement used were analyzed. An α = 5% was considered. Results: Forty patients were evaluated, most of them elderly and male. Among the oral nutritional supplements, the high-calorie and high-protein types were more prevalent, with an offer twice a day, average use of 39 days, and total acceptance of the nutritional prescription by only 30% of the patients. This nutritional intervention resulted in a slight improvement in anthropometric data, with no significant difference. Conclusion: Using the oral nutritional supplement for a longer period and better adherence would possibly present greater nutritional benefits to patients.
Acceptance of the Use of Artificial Intelligence in Medicine Among Japan’s Doctors and the Public: A Questionnaire Survey
Authors: Tamori Honoka , Yamashina Hiroko , Mukai Masami , Morii Yasuhiro , Suzuki Teppei , Ogasawara Katsuhiko
Published: December 2021

Background

The use of artificial intelligence (AI) in the medical industry promises many benefits, so AI has been introduced to medical practice primarily in developed countries. In Japan, the government is preparing for the rollout of AI in the medical industry. This rollout depends on doctors and the public accepting the technology. Therefore it is necessary to consider acceptance among doctors and among the public. However, little is known about the acceptance of AI in medicine in Japan.

Objective

This study aimed to obtain detailed data on the acceptance of AI in medicine by comparing the acceptance among Japanese doctors with that among the Japanese public.

Methods

We conducted an online survey, and the responses of doctors and members of the public were compared. AI in medicine was defined as the use of AI to determine diagnosis and treatment without requiring a doctor. A questionnaire was prepared referred to as the unified theory of acceptance and use of technology, a model of behavior toward new technologies. It comprises 20 items, and each item was rated on a five-point scale. Using this questionnaire, we conducted an online survey in 2018 among 399 doctors and 600 members of the public. The sample-wide responses were analyzed, and then the responses of the doctors were compared with those of the public using t tests.

Results

Regarding the sample-wide responses (N=999), 653 (65.4%) of the respondents believed, in the future, AI in medicine would be necessary, whereas only 447 (44.7%) expressed an intention to use AI-driven medicine. Additionally, 730 (73.1%) believed that regulatory legislation was necessary, and 734 (73.5%) were concerned about where accountability lies. Regarding the comparison between doctors and the public, doctors (mean 3.43, SD 1.00) were more likely than members of the public (mean 3.23, SD 0.92) to express intention to use AI-driven medicine (P<.001), suggesting that optimism about AI in medicine is greater among doctors compared to the public.

Conclusions

Many of the respondents were optimistic about the role of AI in medicine. However, when asked whether they would like to use AI-driven medicine, they tended to give a negative response. This trend suggests that concerns about the lack of regulation and about accountability hindered acceptance. Additionally, the results revealed that doctors were more enthusiastic than members of the public regarding AI-driven medicine. For the successful implementation of AI in medicine, it would be necessary to inform the public and doctors about the relevant laws and to take measures to remove their concerns about them.
The Efficacy of a Smartphone-Based App on Stress Reduction: Randomized Controlled Trial
Authors: Hwang Hyunchan , Kim Sun Mi , Netterstrøm Bo , Han Doug Hyun
Published: December 2021

Background

Stress management in the workplace is essential for a healthy mental and physical state. Due to technological advancements, individually tailored therapy and online cognitive behavioral therapy (CBT) are on the rise.

Objective

This study analyzed the efficacy of a smartphone app based on third-wave CBT tailored to an individual.

Methods

A randomized controlled trial was conducted with 126 participants who were divided into 2 groups. The intervention group used the smartphone app BetterLife for 10 weeks, while the control group was placed on a waiting list for the same duration. The Perceived Stress Scale–10 (PSS), Korean Utrecht Work Engagement Scale–9 (UWES), World Health Organization Quality of Life Assessment (WHOQOL), Beck Depression Inventory–II (BDI), and Beck Anxiety Inventory (BAI) were administered at baseline and after 10 weeks to both groups.

Results

Of the 126 participants, 11 dropped out during the trial. A 2-way repeated measure analysis of covariance was conducted, controlling for baseline BDI. There were greater improvements in PSS (F=24.33, P<.001, η2=0.17) and UWESK scores (F=8.32, P=.0046, η2=0.06) in the intervention group than in the control group. WHOQOL scores exhibited statistically significant improvement in the intervention group in the overall quality of life (F=8.19, P=.0049, η2=0.06), physical health (F=8.87, P=.003, η2=0.07), psychological health (F=13.32, P<.001, η2=0.10), social relationships (F=19.43, P<.001, η2=0.14), and environmental domains (F=10.14, P=.002, η2=0.08) but not overall health (F=1.68, P=.20). BDI (F=7.17, P=.008, η2=0.06) and BAI (F=6.00, P=.02, η2=0.05) showed a statistically significant improvement in the intervention group, but this significance did not survive the Bonferroni correction (P<.005).

Conclusions

These results provide evidence that smartphone-based CBT is a viable option for reducing stress in the workplace.

Trial Registration

Clinical Research Information Service KCT0003231; https://cris.nih.go.kr/cris/search/detailSearch.do/15137
Egyptian Students Open to Digital Mental Health Care: Cross-Sectional Survey
Authors: Mamdouh Mostafa , Tai Andy Man Yeung , Westenberg Jean Nicolas , Shams Farhud , Jang Kerry , Badawy Adel , Elsawi Houssam , Krausz Michael
Published: December 2021

Background

In Egypt, the shortage of mental health services, particularly for adolescents and young adults, is apparent. Electronic mental health (EMH) has been proposed as a solution to bridge the gap and better address the needs of young people. However, EMH is new to Egypt and its acceptability among target populations is crucial to its implementation and success.

Objective

The objective of this study is to explore the interest of Egyptian youth in EMH, identify perceived barriers to EMH, and inform the design of EMH tools to best address the needs of youth.

Methods

A web-based cross-sectional survey was distributed among medical students at Tanta University in Egypt. Chi-square and one-way analysis of variance tests were performed for inferential analyses using a significance level of .05.

Results

Of the 707 individuals who completed the survey (90.9% response rate), 60.5% (428) were female, 62% (438) lived in urban and suburban areas, and the mean age of the sample was 20.5 (SD 1.8) years. The vast majority of participants (522/707, 73.8%) had already used the internet to find information about mental health problems, but the information was unsatisfactory for about half of them (386/707, 54.6%). Almost all students reported that they would prefer web-based therapy if EMH were available through a trustworthy national web-based platform for youth mental health (601/707, 85%). Students believed that emotional difficulties, social support, and coping strategies were the main topics that EMH should help with. The most common perceived barriers for EMH use in Egypt were concerns about privacy (382/707, 54%) and a lack of technology literacy and unfamiliarity with EMH (352/707, 50%).

Conclusions

EMH is a promising strategy for addressing gaps in the mental health care for young people. To construct and implement a digital system of care that addresses the unique needs and preferences of youth, adolescents and young adults should be involved in the co-development and design.