bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolutionary history of the medaka long-wavelength sensitive genes and effects of artificial regression by gene loss on behavioural photosensitivity
Authors: Harada Yumi , Matsuo Megumi , Kamei Yasuhiro , Goto Mayuko , Fukamachi Shoji
Published: February 2019

Tandem gene duplication has led to an expansion of cone-opsin repertoires in many fish, but the resulting functional advantages have only been conjectured without empirical demonstration. Medaka (Oryzias latipes and O. sakaizumii) have eight (two red, three green, two blue, and one violet) cone opsin genes. Absorbance maxima (λmax) of the proteins vary from 356 nm to 562 nm, but those of the red opsins (long-wavelength sensitive; LWS) are nearly identical, obscuring the necessity of their coexistence. Here, we compared the LWSa and LWSb loci of these sister species and found that the gene duplication occurred long before the latipes–sakaizumii speciation (4–18 million years ago), and the high sequence similarity between the paralogues is the result of at least two events of gene conversion. These repetitive gene conversions would indicate the importance for medaka of retaining two identical LWSs in the genome. However, a newly established medaka mutant with a single LWS showed no defect in LWS expression or behavioural red-light sensitivity, demonstrating functional redundancy of the paralogs. Thus, as with many other genes after whole-genome duplication, the redundant LWS might be on the way to being lost from the current cone opsin repertoire. Thus, non-allelic gene conversion may temporarily provide an easier and more frequent solution than gene loss for reducing genetic diversity, which should be considered when assessing history of gene evolution by phylogenetic analyses.
Hard particle force in a soft fracture
Authors: Sun Jichao
Published: February 2019

The fissure patency of a rock mass is an important factor contributing towards the fluid production efficiency. Debris particles generated by the crushing of rock masses or other external forces can cause blockage or promote the smoothness of rock fractures. It is of immense theoretical and engineering value to analyze the mechanics of particles in rock fissures, especially under the compression of rock from both sides. In this study, through static analysis, the resultant force of particles in rock fissures is extruded by rock on both sides. The following conclusions are drawn: The resultant force increases first and then decrease with the increase of fissure angle and width when x is constant. The extreme point is at sinθ = R/(3x), h = 2 R(9x2 − R2)0.5/(9x) and the maximum of F is 8πkR4/(27x). Whereas, the bigger the joint roughness coefficient (JRC) of fissure is, the larger the average of fissure open angle is and the larger the average width is. As the JRC increases, the average resultant force decreases. The sharp point at the turning point of the fissure is easily broken, and the fissure width becomes larger, which makes the resultant force decrease. The analysis process expands the application prospects of the JRC. The results help to better understand the blockage and transport of particles in rock fissures.
Artificial intelligence for precision oncology: beyond patient stratification
Authors: Azuaje Francisco
Published: February 2019

The data-driven identification of disease states and treatment options is a crucial challenge for precision oncology. Artificial intelligence (AI) offers unique opportunities for enhancing such predictive capabilities in the lab and the clinic. AI, including its best-known branch of research, machine learning, has significant potential to enable precision oncology well beyond relatively well-known pattern recognition applications, such as the supervised classification of single-source omics or imaging datasets. This perspective highlights key advances and challenges in that direction. Furthermore, it argues that AI’s scope and depth of research need to be expanded to achieve ground-breaking progress in precision oncology.
A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids
Authors: Phan Nhan , Hong Jenny J. , Tofig Bobby , Mapua Matthew , Elashoff David , Moatamed Neda A. , Huang Jin , Memarzadeh Sanaz , Damoiseaux Robert , Soragni Alice
Published: February 2019

Tumor organoids maintain cell–cell interactions, heterogeneity, microenvironment, and drug response of the sample they originate from. Thus, there is increasing interest in developing tumor organoid models for drug development and personalized medicine applications. Although organoids are in principle amenable to high-throughput screenings, progress has been hampered by technical constraints and extensive manipulations required by current methods. Here we introduce a miniaturized method that uses a simplified geometry by seeding cells around the rim of the wells (mini-rings). This allows high-throughput screenings in a format compatible with automation as shown using four patient-derived tumor organoids established from two ovarian and one peritoneal high-grade serous carcinomas and one carcinosarcoma of the ovary. Using our automated screening platform, we identified personalized responses by measuring viability, number, and size of organoids after exposure to 240 kinase inhibitors. Results are available within a week from surgery, a timeline compatible with therapeutic decision-making.
Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Authors: Shigemizu Daichi , Akiyama Shintaro , Asanomi Yuya , Boroevich Keith A. , Sharma Alok , Tsunoda Tatsuhiko , Matsukuma Kana , Ichikawa Makiko , Sudo Hiroko , Takizawa Satoko , Sakurai Takashi , Ozaki Kouichi , Ochiya Takahiro , Niida Shumpei
Published: February 2019

Alzheimer’s disease (AD) is the most common subtype of dementia, followed by Vascular Dementia (VaD), and Dementia with Lewy Bodies (DLB). Recently, microRNAs (miRNAs) have received a lot of attention as the novel biomarkers for dementia. Here, using serum miRNA expression of 1,601 Japanese individuals, we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia. The final risk prediction model achieved a high accuracy of 0.873 on a validation cohort in AD, when using 78 miRNAs: Accuracy = 0.836 with 86 miRNAs in VaD; Accuracy = 0.825 with 110 miRNAs in DLB. To our knowledge, this is the first report applying miRNA-based risk prediction models to a dementia prospective cohort. Our study demonstrates our models to be effective in prospective disease risk prediction, and with further improvement may contribute to practical clinical use in dementia.
Micro-Raman imaging of isomeric segregation in small-molecule organic semiconductors
Authors: Huang Chiung-Wei , You Xiao , Diemer Peter J. , Petty Anthony J. , Anthony John E. , Jurchescu Oana D. , Atkin Joanna M.
Published: February 2019

Charge transport in organic semiconductors is highly sensitive to film heterogeneity and intermolecular interactions, but probing these properties on the length scales of disorder is often difficult. Here we use micro-Raman spectroscopy to assign vibrational modes of isomerically pure syn and anti 2,8-difluoro-5,11-bis(triethylsilylethynyl)anthradithiophene (diF-TES ADT) by comparing to density functional theory calculations. With polarization-dependent measurements, we determine the orientation of crystallites in pure isomers. In mixed-isomer samples, we observe narrow linewidths and superposition spectra, indicating coexistence of isomerically pure sub-domains on length scales smaller than the probe area. Using the ring breathing modes close to 1300 cm−1 as indicators of the pure isomer crystalline sub-domains, we image their spatial distribution with 200-nm resolution. These results demonstrate the power of micro-Raman spectroscopy for investigating spatial heterogeneities and clarifying the origin of the reduced charge carrier mobility displayed in mixed-isomer diF-TES ADT.
Using castor oil to separate microplastics from four different environmental matrices
Authors: Mani Thomas , Frehland Stefan , Kalberer Andreas , Burkhardt-Holm Patricia
Published: February 2019

An affordable, low-risk and quick method for the separation of microplastics from four environmental matrices based on castor oil.
Non-contact light-radiation thermal desorption-assisted LTP ionization miniature ion trap mass spectrometry for rapid analysis of the flavouring substances in pipe tobacco
Authors: Song Chenchen , Wang Shuang , Wang Weimin , Xu Chuting , Chai Guobi , Ji Lingbo , Zhang Jianxun , Yang Weiping , Zhao Wuduo
Published: February 2019

Non-contact light-radiation heating-assisted desorption for flavouring substance.
Substituting copolymeric poly(alkylenetetrasulfide) for elemental sulfur to diminish the shuttling effect of modified intermediate polysulfides for high-performance lithium–sulfur batteries
Authors: Zhou He , Yu Faqi , Wei Min , Su Yunlan , Ma Yuchen , Wang Dujin , Shen Qiang
Published: February 2019

Substituting linear copolymer poly(methylenetetrasulfide) for molecular S8 could introduce one or two –CH2– units in-between the S–S bond of an intermediate polysulfide, proved by both experimental tests and first-principle calculations.
Preparation of smectic itraconazole nanoparticles with tunable periodic order using microfluidics-based anti-solvent precipitation
Authors: Chen Huijun , Zhang Xiong , Cheng Yi , Qian Feng
Published: February 2019

A microfluidics-based anti-solvent precipitation approach was developed to generate liquid crystalline nanoparticles of itraconazole in a controllable manner. The size, morphology and the structure of nanoparticles were investigated under different precipitation temperatures.
A study on the comprehension of differences in specific kinetic energy of TKX-50 and HMX from the perspective of gas products
Authors: Zhao Chuande , Chi Yu , Peng Qiang , Yang Fang , Zhou Jianhua , Wang Xinfeng , Yu Kun , Fan Guijuan , Sun Jie
Published: February 2019

5,5′-Bitetrazole-1,1′-dioxydihydroxylamine salt (TKX-50), a high-energy energetic material, possesses good safety and energy properties.
Understanding the differences between iron and palladium in cross-coupling reactions
Authors: Sun Xiaobo , J. Rocha Marcus V. , Hamlin Trevor A. , Poater Jordi , Bickelhaupt F. Matthias
Published: February 2019

We aim at developing design principles, based on quantum chemical analyses, for a novel type of iron-based catalysts that mimic the behavior of their well-known palladium analogs in the bond activation step of cross coupling reactions.
Impact of confinement in multimolecular inclusion compounds of melamine and cyanuric acid
Authors: Petelski Andre Nicolai , Pamies Silvana Carina , Sejas Agustín Gabriel , Peruchena Nélida María , Sosa Gladis Laura
Published: February 2019

Cyanuric acid is shown to be the best supramolecular building block to obtain cage-like clusters. Its triazine ring is also superior to the melamine one for capturing anions as well as cations.
Reactivity trends of the MoVOxmixed metal oxide catalyst from density functional modeling
Authors: Li Wen-Qing , Fjermestad Torstein , Genest Alexander , Rösch Notker
Published: February 2019

We studied how polarons affect the oxidative dehydrogenation of hydrocarbons in a MoVOxsurface model and the related surface hydrolysis.
The spectroelectrochemical behaviour of redox-active manganese salen complexes
Authors: Solomon Marcello B. , Chan Bun , Kubiak Clifford P. , Jolliffe Katrina A. , D'Alessandro Deanna M.
Published: February 2019

A series of discrete, functionalised Mn(iii) pyridyl salen metal complexes with varying aliphatic and aromatic bridging diamines have been evaluated and their spectroelectrochemical properties probed.
Proteomics and antioxidant enzymes reveal different mechanisms of toxicity induced by ionic and nanoparticulate silver in bacteria
Authors: Barros Diana , Pradhan Arunava , Mendes Vera M. , Manadas Bruno , Santos Pedro M. , Pascoal Cláudia , Cássio Fernanda
Published: February 2019

Ag+had stronger effects than AgNPs on the growth ofPseudomonassp. M1. Responses of metabolic, energetic and stress pathways to Ag+and AgNP exposure suggested distinct mechanisms of toxicity.
Postprandial metabolomics: GC-MS analysis reveals differences in organic acid profiles of impaired fasting glucose individuals in response to highland barley loads
Authors: Liu Rui , Zhao Jinhui , Guo Jing , Liu Xiaowei , Yu Jiaying , Wang Hanming , Li Ying , Sun Changhao , Liu Liyan
Published: February 2019

The HB load producing low postprandial glucose and insulin responses brings about several alterations in organic acids.
Ultra-trace element analysis of human follicular fluid by ICP-MS/MS: pre-analytical challenges, contamination control, and matrix effects
Authors: Galusha Aubrey L. , Haig Aubreian C. , Bloom Michael S. , Kruger Pamela C. , McGough Alexandra , Lenhart Nikolaus , Wong Rebecca , Fujimoto Victor Y. , Mok-Lin Evelyn , Parsons Patrick J.
Published: February 2019

Human follicular fluid was collected from 56 women undergoing IVF treatment and analyzed for 11 (ultra-)trace elements using a “dilute and shoot” ICP-MS/MS method.
Identification and biological evaluation of novel benzothiazole derivatives bearing a pyridine-semicarbazone moiety as apoptosis inducers via activation of procaspase-3 to caspase-3
Authors: Ma Junjie , Ni Xin , Gao Yali , Huang Kun , Liu Jiaan , Wang Yu , Chen Roufen , Wang Cuifang
Published: February 2019

A series of benzothiazole derivatives bearing a pyridine-semicarbazone moiety were identified as apoptosis inducers via activation of procaspase-3 to caspase-3.
Nanofibrous rhodium with a new morphology for the hydrogenation of CO2to formate
Authors: Zahedifar Mahboobeh , Zhiani Rahele , Sadeghzadeh Seyed Mohsen , Shamsa Farzaneh
Published: February 2019

Herein, fibrous rhodium (Rh) was engineered using a microemulsion system.
Mechanochromic fluorescence based on a combination of acceptor and bulky donor moieties: tuning emission color and regulating emission change direction
Authors: Ishi-i Tsutomu , Tanaka Honoka , Youfu Ryusuke , Aizawa Naoya , Yasuda Takuma , Kato Shin-ichiro , Matsumoto Taisuke
Published: February 2019

Mechanochromic fluorescence based on a conventional strategy using a donor–acceptor structure bearing nonplanar three-dimensional donor moieties was studied.
Long-lived ionic nano-domains can modulate the stiffness of soft interfaces
Authors: Trewby William , Faraudo Jordi , Voïtchovsky Kislon
Published: February 2019

Water-mediated correlations between metal ions enables the formation of long-lived nano-networks at the surface of bilayers in solution. These networks locally change the stiffness of the membrane.
Controllable synthesis of nickel sulfide nanocatalysts and their phase-dependent performance for overall water splitting
Authors: Zheng Xuerong , Han Xiaopeng , Zhang Yiqi , Wang Jihui , Zhong Cheng , Deng Yida , Hu Wenbin
Published: February 2019

This work demonstrates the controllable synthesis of nickel sulfide nanocatalysts and the phase/composition dependent performance for catalyzing overall water-splitting.
Alternating-current driven quantum-dot light-emitting diodes with high brightness
Authors: Xia Fengtian , Sun Xiao Wei , Chen Shuming
Published: February 2019

Highly bright alternating-current (AC) driven quantum-dot light-emitting diodes (QLEDs) are demonstrated based on a single dielectric layer structure.
Polyacryloyl hydrazide incorporation into ionic hydrogels improves toughness, elasticity, self-healability, adhesive & strain sensing properties
Authors: Mandal Subhankar , Pandey Niharika , Singh Somendra , Ranjan Amit , Ojha Umaprasana
Published: February 2019

Polyacryloyl hydrazide incorporation improves the toughness of ionic hydrogels & imparts self-healability and adhesive properties.
Synthesis, characterization and activity performance of nickel-loaded spent FCC catalyst for pine gum hydrogenation
Authors: Chen Xiaopeng , Ren Lu , Yaseen Muhammad , Wang Linlin , Liang Jiezhen , Liang Ruixue , Chen Xiankun , Guo Huiqing
Published: February 2019

A Ni-based catalyst supported over a spent fluid catalytic cracking (FCC) catalyst was prepared by a wet impregnation method.
Inactivation of antibiotic-resistant bacteria by chlorine dioxide in soil and shifts in community composition
Authors: Wu M. S. , Xu X.
Published: February 2019

Antibiotic-resistant bacteria are common widespread in soil and the most resistant species isStaphylococcus aureus.Sphingomonas,ArthrobacterandMassiliaare sensitive to ClO2.MicromonosporaceaeandThaumarchaeotaare more resistant to ClO2.
Carbon quantum dots and their biomedical and therapeutic applications: a review
Authors: Molaei Mohammad Jafar
Published: February 2019

The biomedical applications of the recently emerging carbon quantum dots are reviewed.
A non-enzymatic glucose sensor based on electrospun 3-D copper oxide micro-nanofiber network films using carboxylic-functionalized poly(arylene ether ketone)s as templates
Authors: Liu Mengzhu , Wang Yongpeng , Zhang Haibo , Jiang Zhenhua
Published: February 2019

3-D network films of rope-like CuO-MNFs with high surface-to-volume ratio were prepared. The product is a promising electrode material for fabrication of amperometric enzymeless glucose sensors.
Integral structured Co–Mn composite oxides grown on interconnected Ni foam for catalytic toluene oxidation
Authors: Jiang Xueding , Xu Weicheng , Lai Shufeng , Chen Xin
Published: February 2019

A series of Co–Mn oxides with different Co/Mn molar ratios grown on interconnected Ni foam were prepared as monolithic catalysts for total toluene oxidation.
A novel route to the synthesis of an Fe3O4/h-BN 2D nanocomposite as a lubricant additive
Authors: Zhao Jun , Chen Guangyan , He Yongyong , Li Shuangxi , Duan Zhiqiang , Li Yingru , Luo Jianbin
Published: February 2019

The Fe3O4 nanoparticles are uniformly dispersed on the 2D-layered surfaces of h-BN nanosheets. This novel Fe3O4/h-BN 2D nanocomposite displays excellent tribological properties due to synergetic lubricating effect.
Ultradispersed titanium dioxide nanoparticles embedded in a three-dimensional graphene aerogel for high performance sulfur cathodes
Authors: Liu Mengmeng , Zhu Xiaohang , Ma Tianye , Zhang Congcong , Chen Xiang , Zhang Xiuhui , Huang Tao , Li Wei , Yu Aishui
Published: February 2019

GA–TiO2 composites as a cathode material realize an excellent electrochemical performance in Li–S batteries.
Kinetic study on the grain growth of PuO2 nanocrystals
Authors: Bouëxière Daniel , Popa Karin , Walter Olaf , Cologna Marco
Published: February 2019

Results on the kinetics of PuO2 nanocrystals are presented in the temperature range below 1100 °C showing the activation energy for the particle growth is ∼350 kJ mol−1. Particle growth proceeds from the nano- to the micrometer scale.
Electro-deposition for asphaltene removal during heavy oil upgrading
Authors: Xia Shunxiang , Veony Enjelia , Kostarelos Konstantinos
Published: February 2019

Blending crude oil with short-chain paraffins is a common method to improve the oil quality during heavy oil upgrading.
Synergistic enhancement of gas selectivity in thin film composite membranes of PIM-1
Authors: Borisov Ilya , Bakhtin Danila , Luque-Alled Jose M. , Rybakova Anastasiya , Makarova Veronika , Foster Andrew B. , Harrison Wayne J. , Volkov Vladimir , Polevaya Viktoria , Gorgojo Patricia , Prestat Eric , Budd Peter M. , Volkov Alexey
Published: February 2019

A new series of thin film composite membranes with high CO2 permeance (up to 8000 GPU) and CO2/N2 selectivity (up to 55.7) was designed and fabricated via coating PIM-1 solution in a mixture of chloroform and trichloroethylene on top of a cross-linked PTMSP gutter layer.
Highly efficient nitrogen and carbon coordinated N–Co–C electrocatalysts on reduced graphene oxide derived from vitamin-B12 for the hydrogen evolution reaction
Authors: Sabhapathy Palani , Liao Chen-Cheng , Chen Wei-Fu , Chou Tsu-Chin , Shown Indrajit , Sabbah Amr , Lin Yan-Gu , Lee Jyh-Fu , Tsai Ming-Kang , Chen Kuei-Hsien , Chen Li-Chyong
Published: February 2019

A simple strategy was used to tune the electronic structure and d-band center of Co–Nxto achieve the best electrochemical hydrogen evolution reaction.
An in situ anion exchange induced high-performance oxygen evolution reaction catalyst for the pH-near-neutral potassium borate electrolyte
Authors: Dong Yan , Komarneni Sridhar , Wang Ni , Hu Wencheng , Huang Wenyan
Published: February 2019

A high-performance NiFe LDH oxygen evolution reaction catalyst for the pH-near-neutral potassium borate electrolyte obtained by an in situ anion exchange process.
High density graphene–carbon nanosphere films for capacitive energy storage
Authors: Díez Noel , Qiao Mo , Gómez-Urbano Juan Luis , Botas Cristina , Carriazo Daniel , Titirici Maria Magdalena
Published: February 2019

High-density self-standing graphene/CNS films with high volumetric capacitance, good capacitance retention and excellent cycling performance.
Thermodynamic maximum of Y doping level in barium zirconate in co-sintering with NiO
Authors: Ueno Katsuhiro , Hatada Naoyuki , Han Donglin , Uda Tetsuya
Published: February 2019

2 phase equilibrium of Y-doped BaZrO3 and NiO is only achievable when the doping level is less than 12 mol%.
Mordant inspired wet-spinning of graphene fibers for high performance flexible supercapacitors
Authors: He Nanfei , Shan Weitao , Wang Julia , Pan Qin , Qu Jiangang , Wang Guofeng , Gao Wei
Published: February 2019

Al3+ coagulated wet-spun graphene fibers show a large surface area and high electrical conductivity, resulting in large capacitance.
A green electrochemical transformation of inferior coals to crystalline graphite for stable Li-ion storage
Authors: Zhu Zhenglu , Zuo Haibin , Li Shijie , Tu Jiguo , Guan Wei , Song Wei-Li , Zhao Jun , Tian Donghua , Jiao Shuqiang
Published: February 2019

With the increasing demand for the efficient utilization of global resources, a green strategy for the transformation of inferior coals to highly value-added products is demonstrated.
An all superantiwetting surface in water–oil–air systems
Authors: Tie Lu , Li Jing , Guo Zhiguang , Liang Yongmin , Liu Weimin
Published: February 2019

Six superantiwetting states, superhydrophobicity, superoleophobicity, underoil superhydrophobicity, underwater superoleophobicity, and underoil and underwater superaerophobicity, are realized on one surface. The all superantiwetting surface can be extended to polar liquid–nonpolar liquid–air systems and be used for on-demand separation of immiscible organic liquids.
Simple and efficient rhodamine-derived VO2+ and Cu2+-responsive colorimetric and reversible fluorescent chemosensors toward the design of multifunctional materials
Authors: Jiang Daoyong , Xue Xingying , Zhang Guoning , Wang Yucheng , Zhang Han , Feng Chao , Wang Zhifei , Zhao Hong
Published: February 2019

A simple and versatile VO2+ and Cu2+ responsive colorimetric and reversible fluorescent rhodamine scaffold towards designing multifunctional materials.
Enzyme-triggeredin situformation of Ag nanoparticles with oxidase-mimicking activity for amplified detection of alkaline phosphatase activity
Authors: Song Hongwei , Li Zhibo , Peng Yinxian , Li Xin , Xu Xuechao , Pan Jianming , Niu Xiangheng
Published: February 2019

ALP-triggeredin situformation of Ag NPs with high oxidase-mimicking activity for colorimetric detection of alkaline phosphatase activity.
Blue quantum dot light-emitting diodes with high luminance by improving the charge transfer balance
Authors: Li Dongyu , Bai Jinke , Zhang Tingting , Chang Chun , Jin Xiao , Huang Zhen , Xu Bing , Li Qinghua
Published: February 2019

A TBS-PBO based blue QLED delivers a notable luminance of 4635 cd m−2 at an EQE maximum of 17.4%.
Towards a hexa-branched [7]rotaxane from a [3]rotaxane via a [2+2+2] alkyne cyclotrimerization process
Authors: Mao Min , Zhang Xiu-Kang , Xu Tian-Yi , Wang Xiao-Dong , Rao Si-Jia , Liu Yue , Qu Da-Hui , Tian He
Published: February 2019

Herein we report a facile synthetic route for the preparation of a hexa-branched [7]rotaxane by using Co-catalyzed [2+2+2] alkyne cyclotrimerization from a [3]rotaxane.
Enhanced thermal transport across a bi-crystalline graphene–polymer interface: an atomistic approach
Authors: Verma Akarsh , Kumar Rajesh , Parashar Avinash
Published: February 2019

The objective of this investigation was to elaborate on the influence of grain boundaries on the interfacial thermal conductance between bi-crystalline graphene and polyethylene in a nanocomposite.
The past, present, and future in the nomenclature and structure representation of inorganic compounds
Authors: Hartshorn Richard M. , Yerin Andrey
Published: February 2019

Where we have been and where we are going in precisely describing structures of inorganic compounds.
Amino functionalized Zn/Cd-metal–organic frameworks for selective CO2 adsorption and Knoevenagel condensation reactions
Authors: Zhai Zhi-Wei , Yang Shuang-Hua , Lv Ya-Ru , Du Chen-Xia , Li Lin-Ke , Zang Shuang-Quan
Published: February 2019

Two amino functionalized Zn/Cd-MOFs can be employed to adsorb CO2 selectively and to catalyze Knoevenagel reactions under solvent-free conditions.
Electrochemical dehydrogenation of hydrazines to azo compounds
Authors: Du Ke-Si , Huang Jing-Mei
Published: February 2019

A strategy for the electrochemical dehydrogenation of hydrazine compounds is disclosed under ambient conditions. Its synthetic value is well demonstrated by the highly efficient synthesis of symmetric and unsymmetric azo compounds. It is an environmentally friendly transformation and the present protocol was effective on a large scale.
Constituent-tunable ternary CoM2xSe2(1−x)(M = Te, S) sandwich-like graphitized carbon-based composites as highly efficient electrocatalysts for water splitting
Authors: Wang Yu , Liu Li , Wang Yanwei , Fang Ling , Wan Fu , Zhang Huijuan
Published: February 2019

Herein, we synthesized two groups of component-controllable sandwich-like CoTe2xSe2(1−x)and CoS2ySe2(1−y)graphitized carbon-based catalysts for the first time.
Palladium-catalyzed allylic C–H oxidation under simple operation and mild conditions
Authors: Guo Yunlong , Shen Zengming
Published: February 2019

We discovered an effective and simple system (Pd/BQ/air/r.t.) for making allylic alcohols through Pd-catalyzed allylic C–H bond functionalization.
Two-dimensional SnS2 nanosheets exfoliated from an inorganic–organic hybrid with enhanced photocatalytic activity towards Cr(vi) reduction
Authors: Liu Yongping , Mi Xihong , Wang Jixiang , Li Ming , Fan Dayong , Lu Huidan , Chen Xiaobo
Published: February 2019

Thin SnS2 nanosheets with {001} facets dominating were obtained with the liquid-exfoliation method and exhibit largely improved photocatalytic activity for Cr(vi) reduction.
Rational design of NiFe2O4–rGO by tuning the compositional chemistry and its enhanced performance for a Li-ion battery anode
Authors: Zhang Yanlan , Cao Wenqiang , Cai Yongzhu , Shu Jincheng , Cao Maosheng
Published: February 2019

NiFe2O4–rGO is reasonably designed; meanwhile, the excellent lithium storage can be readily tuned by tuning the compositional chemistry.
Synthesis of benzimidazolones by immobilized gold nanoparticles on chitosan extracted from shrimp shells supported on fibrous phosphosilicate
Authors: Zahedifar Mahboobeh , Es-haghi Ali , Zhiani Rahele , Sadeghzadeh Seyed Mohsen
Published: February 2019

We demonstrate the synthesis of benzimidazolones from o-phenylenediamines and CO2 in the presence of gold nanoparticles supported on a composite material based on microcrystalline chitosan from shrimp shells and fibrous phosphosilicate.
Aminoazobenzene@Ag modified meshes with large extent photo-response: towards reversible oil/water removal from oil/water mixtures
Authors: Qu Ruixiang , Liu Yanan , Zhang Weifeng , Li Xiangyu , Feng Lin , Jiang Lei
Published: February 2019

A large-extent photo-responsive wettability transformation is realized by aminoazobenzene@Ag to selectively remove oil/water.
Room temperature demonstration of a sodium superionic conductor with grain conductivity in excess of 0.01 S cm−1 and its primary applications in symmetric battery cells
Authors: Ma Qianli , Tsai Chih-Long , Wei Xian-Kui , Heggen Marc , Tietz Frank , Irvine John T. S.
Published: February 2019

The lack of suitable candidate electrolyte materials for practical application limits the development of all-solid-state Na-ion batteries.
Surface P atom grafting of g-C3N4 for improved local spatial charge separation and enhanced photocatalytic H2 production
Authors: Tian Xiao , Sun Ying-jie , He Jiang-yan , Wang Xiao-jing , Zhao Jun , Qiao Shi-zhang , Li Fa-tang
Published: February 2019

A new surface P atom-grafted g-C3N4 is developed, and the existence form and function of P atom is presented.
Surface modifications of boron nitride nanosheets for poly(vinylidene fluoride) based film capacitors: advantages of edge-hydroxylation
Authors: Wu Lingyu , Wu Kai , Lei Chuxin , Liu Dingyao , Du Rongni , Chen Feng , Fu Qiang
Published: February 2019

Three different types of modified BNNSs were designed to experimentally demonstrate the importance of integrated basal crystal lattices for polymer/BNNSs film capacitors.
Mo-doped Ni2P hollow nanostructures: highly efficient and durable bifunctional electrocatalysts for alkaline water splitting
Authors: Wang Qin , Zhao Hongyang , Li Fumin , She Wenyan , Wang Xiaoming , Xu Ling , Jiao Huan
Published: February 2019

It was found that Mo-doped Ni2P hollow nanostructures display excellent hydrogen evolution reaction and oxygen evolution reaction performance.
Sky-blue fluorescent small-molecules with high quantum efficiency: synthesis, structures, AIE properties, and applications in solution-processed non-doped OLEDs
Authors: Li Meijing , Peng Feng , Ying Lei , Xu Jingkun
Published: February 2019

Two sky-blue AIE fluorophores with high quantum efficiency were synthesized and demonstrated superior performances in solution-processed non-doped OLEDs.
Hardy’s uncertainty principle and unique continuation property for stochastic heat equations
Authors: Fernández-Bertolin Aingeru , Zhong Jie
Published: February 2019

The goal of this paper is to prove a qualitative unique continuation property at two points in time for a stochastic heat equation with a randomly perturbed potential, which can be considered as a variant of Hardy’s uncertainty principle for stochastic heat evolutions.
Supply chain encroachment with quality decision and different power structures
Authors: Xue Musen , Zhang Jianxiong
Published: February 2019

This paper studies a supply chain with manufacturer encroachment and different power structures where product quality is an endogenous decision. We investigate the effects of encroachment and power structure on quality and profits for chain members. Employing a game-theoretic approach, we find that, first, in a manufacturer-led supply chain, encroachment makes both manufacturer and retailer better off when the quality investment efficiency is relatively high. And, the manufacturer’s profit exhibits nonmonotonicity with respect to the extent of consumers acceptance on the direct channel in a retailer-led setting. Second, our result shows that the pure equilibrium outcomes are driven by the quality investment efficiency and the extent of consumers’ acceptance on the direct channel. An interesting result is that, for the manufacturer, establishing encroachment channel and occupying the leader position simultaneously are always not the optimal choice. Additionally, the options of encroaching and striving for leader position can lead to lose-win, win-win, and win-lose situations for the manufacturer and the retailer. Finally, a prisoner’s dilemma may occur with a low quality investment efficiency, a moderately fixed encroachment cost and a high extent of consumers’ acceptance on the direct channel when a fixed encroachment cost is considered.
Stillvorbereitung der Eltern
Authors: Nicin Tatjana
Published: February 2019

Mit einer ausführlichen und frühen Information schwangerer Frauen und ihrer Familien über die Bedeutung des Stillens tragen Hebammen entscheidend dazu bei, dass Säuglinge nach der Geburt und in den ersten Lebensjahren optimal versorgt werden. Hebamme, Still- und Laktationsberaterin Tatjana Nicin engagiert sich seit Jahren für eine bessere Elternaufklärung und mehr gesellschaftliche Akzeptanz des Stillens. Für DIE HEBAMME reflektiert sie aus Ihrer klinischen und außerklinischen Erfahrung heraus mögliche Gründe für niedrige Stillraten in Deutschland und gibt konkrete Tipps, um Eltern zum Stillen zu motivieren.
Unterschiede der selbst-berichteten Arbeitsbedingungen in
unterschiedlichen Dienststellen bei der Einführung eines Betrieblichen
Gesundheitsmanagements
Authors: Sammito Stefan , Schöne Klaus , Claus Annika , Rose Dirk-Matthias
Published: February 2019

Ziel der Studie Zum 01.01.2015 wurde im Zuständigkeitsbereich des
Bundesministerium der Verteidigung (BMVg) eine Erprobungsphase zur
Einführung des Betrieblichen Gesundheitsmanagement (BGM) an elf
ausgesuchten Erprobungsdienststellen in Deutschland gestartet. Die Dienststellen
zeigten eine möglichst große Heterogenität in
Zusammensetzung der jeweiligen Belegschaft und den Aufgaben der jeweiligen
Dienststellen. Ziel der Eprobungsphase war es Maßnahmen und Erfahrungen
für die weitere Ausfächerung zu erhalten. Auf Basis einer
Mitarbeiterbefragung wurde der Ist-Zustand zu Beginn der Einführung
erhoben.

Methodik Dies wurde mittels einer freiwilligen Mitarbeiterbefragung bei
allen 9267 Beschäftigten durchgeführt. Hierzu wurde eine
Kombination aus einer webbasierten Onlinebefragung und einer klassischen
Paper-Pencil-Befragung genutzt.

Ergebnisse Insgesamt nahmen 2076 (22,4%) aller
Beschäftigten an der Befragung teil. Es zeigten sich zwischen den
unterschiedlichen Dienststellen in allen Themenblöcke
(„Führungsverhalten/Soziale Aspekte“,
„Arbeitsgestaltung“, „Arbeitsverantwortung“,
„Arbeitsmittel“, „Umgebungsbedingungen“,
„Arbeitsverhalten“, „Psychische Gesundheit“,
„Stress“, „Commitment“,
„Ernährung“ und
„Bewegung/Sport“) mit Ausnahme des Themenblock
„Gesundheitsverhalten“ signifikante Unterschiede.

Schlussfolgerung Die vorliegende Analyse zeigt deutlich, dass bei der
Einführung eines BGM eine dienststellenbezogene Zustandserhebung
notwendig ist, um bedarfsgerecht und zielgerichtet ein bei knappen Ressourcen
sinnvolles BGM durchzuführen.
Leitsätze zur Palliativversorgung und Trauerbegleitung in der Peri- und Neonatologie
Authors: Strahleck Thomas
Published: February 2019

Neugeborene bilden mit fast 40 % die größte Gruppe der Todesfälle im Kindes- und Jugendalter in Deutschland. Die interprofessionelle Projektgruppe PaluTiN (Palliativversorgung und Trauerbegleitung in der Peri- und Neonatologie) hat unter dem Dach des Bundesverbandes Das frühgeborene Kind e. V. Leitsätze für eine zeitgemäße und alle relevanten Aspekte berücksichtigende Palliativversorgung und Trauerbegleitung in der Peri- und Neonatologie erarbeitet 1. Der Autor stellt für die PaluTiN Arbeitsgruppe eine Kurzfassung vor.
Kinder- und jugendpsychiatrische Versorgung von Kindern und Jugendlichen mit Intelligenzminderung und psychischen Störungen in Deutschland
Authors: Haessler Frank , Paeckert Julia , Reis Olaf
Published: February 2019

Fragestellung Versorgungssituation intelligenzgeminderter Kinder und Jugendlicher mit psychischen Auffälligkeiten durch die Kinder- und Jugendpsychiatrie in Deutschland im Jahre 2014, d. h. 10 Jahre nach einer vergleichbaren Erhebung der ersten Versorgungsstudie von Hennicke.

Methodik Postalische Befragung aller Kinder- und Jugendpsychiatrischen Kliniken (n=138) nebst direkter individueller Kontakte durch die Autoren, wobei 46 (33%) antworteten.

Ergebnisse 8 Kliniken (17%) verfügten entweder über ein spezialisiertes ambulantes oder stationäres Angebot, 3 Kliniken (7%) über beides. Der durchschnittliche Anteil stationär versorgter Kinder und Jugendlicher mit Intelligenzminderung (IM) lag bei 6,6%, tagesklinisch bei 7,9% und ambulant bei 3%. Das stationäre Angebot für diese Patientengruppe schätzten 54% der befragten Kliniken als mangelhaft bis ungenügend ein und 43% die ambulante Versorgung. Im Rahmen der Behandlung psychischer Störungen bei intelligenzgeminderten Kindern und Jugendlichen wurden den Standards des Fachgebietes entsprechend verschiedene Behandlungsansätze in Abhängigkeit vom Schweregrad der Behinderung verfolgt. Während der Einsatz funktioneller Übungsbehandlungen und, eltern- und familienbezogener Therapien und anderer umfeldbezogener Interventionen vom Behinderungsgrad unabhängig häufig erfolgte, sank der Einsatz von Psychotherapien mit steigendem Behinderungsgrad der Patienten. – und zwar auf fast die Hälfte des Wertes bei schwer Intelligenzgeminderten im Vergleich zu Lernbehinderten. Zugleich stieg der Anteil verabreichter Psychopharmaka mit steigendem Behinderungsgrad der Patienten deutlich an. Schwer Intelligenzgeminderte erhielten laut den aktuell erhobenen Daten fast doppelt so häufig psychotrope Medikamente (65%) wie Lernbehinderte (37%).

Schlussfolgerung An der insgesamt defizitären Versorgungssituation der psychisch vulnerablen intelligenzgeminderten Kinder und jugendlichen hat sich im Vergleich zu 2004 kaum etwas geändert, auch wenn ein leichter Anstieg der spezialisierten Angebote verzeichnet werden kann. Medikamente kamen seltener zum Einsatz als andere Therapieverfahren. Das Verhältnis des Einsatzes nichtmedikamentöser Behandlungsformen (inkl. Psychotherapie) gegenüber Psychopharmaka in der Therapie psychischer Störungen bei intelligenzgeminderten Kindern und Jugendlichen unabhängig vom Behinderungsgrad zeigt , dass fast ausnahmslos alle nichtmedikamentösen Behandlungsformen verhältnismäßig häufiger eingesetzt wurden als psychotrope Medikamente.
Indikation zur stationären medizinischen Rehabilitation bei Hausarztpatienten mit chronischen psychischen Erkrankungen und Teilhabebeeinträchtigungen
Authors: Muschalla Beate , Linden Michael
Published: February 2019

Hintergrund Psychische Erkrankungen gehen vielfach mit Beeinträchtigungen in der Teilhabe am gesellschaftlichen und beruflichen Leben einher. Es ergibt sich daraus häufig die Indikation für eine stationäre Rehabilitation. Derartige Patienten werden langzeitig v. a. von Hausärzten behandelt, die auch wichtige Vermittler bei der Einleitung einer Rehabilitationsmaßnahme sind. Allerdings weisen die Rentenversicherer darauf hin, dass in vielen Fällen von Erwerbsminderungsrenten vorab keine Rehabilitationsmaßnahme durchgeführt wurde. Es stellt sich die Frage, bei welchen Hausarztpatienten eine Rehabilitationsmaßnahme durchgeführt wird oder durchgeführt werden sollte.

Methode Eine prototypisch repräsentative Stichprobe von 307 Patienten aus 40 Hausarztpraxen wurde von einem psychosomatischen Konsiliararzt untersucht, einschließlich (Reha-)Behandlungsvorgeschichte, Krankheitsstatus und Teilhabe. Es wurde geprüft, welche Behandlungsoptionen vorliegen und ob aktuell eine Rehaindikation vorliegt. Bei der Hälfte der Patienten wurden die Hausärzte über die Konsilempfehlung informiert und ein halbes Jahr später nachgefragt, ob diese umgesetzt wurden.

Ergebnisse Bei 64% der Patienten mit chronischen psychischen Erkrankungen war bislang keine psychosomatische Reha erfolgt und auch keine Indikation gegeben. Bei 5,2% wurde bereits einmal eine stationäre psychosomatische Rehabilitation durchgeführt, und jetzt nicht nochmals eine Rehaindikation gestellt. Bei 27% wurde bislang noch keine Rehamaßnahme durchgeführt, wurde jetzt aber konsiliarärztlich erstmals empfohlen. Bei 3,6% war schon einmal eine psychosomatische Reha durchgeführt worden und dennoch vom Konsiliararzt eine Wiederholungsreha als sinnvoll erachtet. Patienten, die bereits einmal in Reha waren sind kränker und haben mehr Fähigkeits- und Teilhabeprobleme. Patienten, bei denen aus Sicht des Konsilarztes erstmalig eine psychosomatische Rehabilitation erwogen werden sollte, haben primär arbeitsbezogene Probleme und nur zu einem geringeren Ausmaß aktuelle psychische und somatische Beeinträchtigungen. Von 35 Patienten, bei denen der Konsiliararzt die Neubeantragung einer psychosomatischen Rehabilitation empfahl, wurde bei 13 im Verlauf der folgenden 6 Monate ein Antrag gestellt.

Schlussfolgerung Da Hausärzte eine zentrale Position bei der Betreuung von Langzeitkranken mit Teilhabebeeinträchtigungen haben, sollten Maßnahmen zur Förderung einer MBOR-Orientierung auch bei Hausärzten erfolgen. Dazu gehört auch eine verbesserte und erleichterte Kooperation bei der Beantragung von Rehabilitationsmaßnahmen inklusive einer transparenten Begutachtung.
Progression of Albuminuria Among Patients with Type 1 Diabetes Mellitus: A Long Term Observational Follow-up Study
Authors: Stratigou Theodora , Vallianou Natalia , Koutroumpi Stavroula , Vlassopoulou Barbara , Apostolou Theofanis , Tsagarakis Stylianos , Ioannidis George
Published: February 2019

Background The purpose of the present study was to determine whether patients with DM1 have shown improvement, stabilization or deterioration of their urine albumin excretion levels during a close follow-up.

Patients and Methods A cohort of 84 patients, 18–76 years of age, a median duration of diabetes of 24 years (1–50 years) and a median follow-up duration of 12 years (1–37 years) were included in the study.

Results Among the 84 patients for whom we had UAE levels at the beginning and by the end of the study, mean glycosylated hemoglobin was statistically significantly decreased during the follow-up period, from 8.02±2.04–7.06±1.05% (p=0.036). Normoalbuminuria was present in 66 patients and remained so in 56 patients while 9 patients progressed to microalbuminuria and one patient to macroalbuminuria by the end of the study. Microalbuminuria was present in 15 patients: regression was observed in 8 patients, and progression in one patient. Regression of macroalbuminuria to microalbuminuria was noted in one patient and to normoalbuminuria was noted in one participant, too.

Conclusions Improvement of glycemic control with close monitoring of DM1 patients together with the appropriate use ACE or AT2 inhibitors and statins, seems to exert nephron-protective potential and to delay or even reverse the presence of micro/macroalbuminuria. This long term follow-up study has demonstrated a statistically significant increase in serum HDLcholesterol levels. The study also revealed that intensively treated diabetes patients may show reductions in serum ALP levels. Whether this finding is related to diabetic nephropathy, NAFLD, or diabetic hepatosclerosis remains to be assessed in future trials.
Ruthenium-Promoted Acceptorless and Oxidant-Free Lactone Synthesis in Aqueous Medium
Authors: Muthaiah Senthilkumar , Bhatia Anita , Kannan Muthukumar
Published: February 2019

Ruthenium-catalyzed formation of lactones from diols in aqueous medium has been demonstrated. 1,3,5-Triazaphosphaadamantane (PTA) included water-soluble ruthenium complexes [RuCl2(PPh3)(2,6-Py-(CH2-PTA)2]·2Br and [RuCl2(PPh3)2(2-PyCH2PTA)]·Br in the presence of KOH were found to be efficient for the synthesis of lactones from diols. The reported synthetic protocol is green as it uses water as solvent, avoids the use of any hydrogen acceptor/oxidant, and produces hydrogen as the only side product. Mechanistic studies revealed that lactone formation involved aldehyde intermediate and followed dehydrogenative pathway.
Extracorporeal Membrane Oxygenation for Diffuse Alveolar Hemorrhage Caused by Idiopathic Pulmonary Hemosiderosis: A Case Report and a Review of the Literature
Authors: Matsumoto Shotaro , Nakagawa Satoshi
Published: February 2019

Diffuse alveolar hemorrhage (DAH) is a life-threatening condition presenting with hemoptysis, anemia, and diffuse radiographic pulmonary infiltrates; it causes acute respiratory failure. Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of DAH occurring predominantly in children. Bleeding is often considered to be a contraindication for extracorporeal membrane oxygenation (ECMO) due to systemic anticoagulation. We present an 8-year-old girl with DAH caused by IPH. Unfractionated heparin was administered to maintain an activated clotting time of 150 to 180 seconds. The DAH resolved with immunosuppressive therapy, and the patient survived to decannulation. ECMO may be applied as a rescue therapy for DAH even with systemic anticoagulation.
Strain-dependence of χ(2) in thin film barium strontium titanate
Authors: Foster Natalie D. , Edmondson Bryce I. , Ekerdt John G. , Smith David J. , Downer Michael C.
Published: February 2019

Optical second-harmonic generation (SHG) in reflection characterized variations in the second-order nonlinear optical susceptibility χ(2) of Ba1−xSrxTiO3 (BSTO) alloy films grown epitaxially on SrTiO3(001) (STO) as Sr molar ratio x changed from 0 to 1 and thickness from 10 to 50 nm. X-ray diffraction showed that BSTO films with x ≳ 0.1 were highly crystalline and compressively strained with out-of-plane (in-plane) lattice constant 4.09 > c > 3.97 (3.903 < a < 3.907 Å, pinned to substrate) for 0 < x < 1. Spectroscopic ellipsometry showed that the BSTO dielectric function was nearly x-invariant in the range of fundamental (780 nm) and SH (390 nm) wavelengths. SHG intensity peaked at x ∼ 0.3 for a given film thickness, suggesting that composition control can optimize ferroelectric and electro-optic properties of BSTO films grown on STO buffer layers.
Deterministic generation and switching of dissipative Kerr soliton in a thermally controlled micro-resonator
Authors: Lu Zhizhou , Wang Weiqiang , Zhang Wenfu , Chu Sai T. , Little Brent E. , Liu Mulong , Wang Leiran , Zou Chang-Ling , Dong Chun-Hua , Zhao Bailing , Zhao Wei
Published: February 2019

In this paper, we first experimentally demonstrate deterministic generation and switching of dissipative Kerr solitons (DKSs) in a thermally controlled micro-ring resonator based on high-index doped silica glass platform. In our scheme, an auxiliary laser is introduced to timely balance the intra-cavity heat fluctuation. By decreasing the operation temperature through a thermo-electric cooler, primary-, chaotic-comb and soliton crystal are firstly generated, then increasing the temperature, DKSs switching and single soliton are robustly accessed, which is independent of the tuning speed. During the switching process, varieties of DKSs are identified by tens of the characteristic “soliton-steps”. Besides, by simply changing the operation temperature under which the DKSs are formed, the center wavelength of dispersive waves could be tuned in a broadband range. When the micro-ring resonator operating at temperature larger than 63.5 °C, avoided mode-crossing free soliton can be obtained. Our results are favorable for study of on-chip soliton dynamics and practical nonlinear applications.
Non-thermal lattice dynamics in α-quartz induced by femtosecond laser pulses: An
ab initio
study
Authors: Miyamoto Yoshiyuki
Published: February 2019

Laser-patterning techniques are typically based on local-heating phenomena, whereas recently developed short-pulse lasers operating on the order of femtoseconds may also induce non-thermal processes in materials. As it is difficult to study non-thermal processes experimentally, ab initio simulations are crucial for understanding laser-patterning phenomena under these conditions. In this study, real-time time-dependent density functional simulations were performed to examine the kinetic energies of the atoms in a slab of α-quartz under a laser fluence per pulse of 10 J/cm2, a wavelength of 800 nm, and full width at half-maximum (FWHM) values ranging from 10 fs to 100 fs. The simulation results suggested the occurrence of thermal/non-thermal crossover at an FWHM value of approximately 50 fs. Smaller FWHM values resulted in non-thermal lattice dynamics. Even under a lower laser fluence per pulse, a shorter pulse initiated non-thermal dynamics with a duration of several tens of femtoseconds.