bluuebunny/crossref_metadata_2025 huggingface dataset:
ZORUNLU EĞİTİM ÇAĞINI GEÇMİŞ ENGELLİ BİREYLERİN DURUMLARININ İNCELENMESİ
Authors: ERCAN Zülfiye Gül , GÜNDÜZ Feyza Nazan
Published: October 2022

Bu araştırma zorunlu eğitim çağını geçmiş olan engelli bireylerin günümüzdeki durumlarının incelenmesi amacıyla yapılmıştır. Araştırma nitel araştırma yöntemlerinden durum çalışması desenine göre planlanmıştır. Araştırma gönüllük esasına göre engelli yetişkin çocuğu olan yedi aile üzerinde yürütülmüştür. Araştırmanın verileri görüşme tekniği ile toplanmış ve araştırmada yarı yapılandırılmış görüşme formu kullanılmıştır. Elde edilen veriler içerik ve betimsel analiz ile değerlendirilmiştir. Araştırma sonucunda; engelli bireylerin, engel derecelerinin orta ve ağır seviyede olduğu, geçmişte engelli bireylerin tümünün üniversiteye bağlı eğitim-rehabilitasyon merkezinden hizmet aldıkları, ailelerin çocuklarının eğitim süreçlerinde erişilebilirlik ve yemek hizmetlerinde sorun yaşadıkları, alınan eğitimin çocukların akademik, günlük yaşam ve sosyal becerilerine katkı sağladığı bulunmuştur. Ayrıca araştırmada tüm ailelerin çocuklarının geleceklerinden kaygı duydukları, bundan dolayı engelli bireylere yönelik bakım evlerinin kurulmasını istedikleri, engelli çocuklarının eğitimlerinin yaşam boyu yoğun bir şekilde devam etmesi gerekliliğine dikkat çektikleri ve çocuklarının rahatça katılabilecekleri sosyal etkinlikler düzenlenmesinin de önemli olduğunu ifade ettikleri belirlenmiştir.
BRIC ÜLKELERİ İMALAT SANAYİNDE TALEP YANLI YAKLAŞIM: BİR TALEP AYRIŞTIRMASI
Authors: NAS Şahin , ARICIOĞLU Ebru
Published: October 2022

Tarihsel olarak, talep sanayileşme için önemli bir dinamik olmuştur. Buna rağmen sanayileşme politikalarında arz yanlı dinamikler dikkate alınmakta ve talep yanlı dinamikler eksik kalmaktadır. Ancak sürdürülebilir sanayileşme ve büyüme için talep dinamikleri de dikkate alınmalıdır. Bu çerçevede çalışmanın amacı, talep dinamiklerinin ekonomi ve imalat sanayide nasıl bir katkı sağladığını analiz etmektir. Çalışmanın amacı kapsamında, Kranendonk ve Verbruggen (2005; 2008) tarafından önerilen Hollanda yöntemi kullanılarak BRIC ülkelerinde talep ayrıştırması yapılmıştır. Bu ülkelerin WIOD’ta yer alan 2000-2014 dönemine ait Ulusal Girdi-Çıktı Tabloları (NIOTs) kullanılmıştır. Elde edilen bulgulara göre BRIC ülkelerinde yurtiçi nihai talep ekonominin önemli bir dinamiğidir. İmalat sanayide ise Çin hariç yurtiçi nihai talep daha baskındır. Toplam ekonomi ile karşılaştırıldığında yabancı katma değer imalat sanayinde daha yüksektir. Bir diğer önemli bulgu ise 2008-2009 küresel finansal kriz döneminde yurtdışı nihai talep ve yabancı katma değer azalırken, yurtiçi nihai talep ve yurtiçi katma değer artmıştır. Bununla birlikte özellikle gelişmekte olan ülkelerde sanayileşme ve kalkınma sürecinde talebin etkili bir dinamik olabilmesi için reel geliri artırıcı, talep çeşitliliğini ve orta sınıfın genişlemesini sağlayan politikalar üretilmelidir.
TOROSLARDA YAKILAN İSTİKLAL ATEŞİNİN ROMANI KAYIP SANCAK’TA YAPI VE İZLEK
Authors: YASAV Cansu
Published: October 2022

Geçmişte yaşanan olayların yazarların muhayyilesinde yeniden yorumlanarak kurgulanması sonucu meydana gelen tarihî romanlar, kimi yazarlar tarafından millî kimliği oluşturan değerleri muhafaza etmek ve millî bilinci uyanık tutmak amacıyla kaleme alınır. Türk edebiyatında geçmişten günümüze birçok tarihî roman kaleme alınmıştır. Mehmet Uluğtürkan’ın kaleme aldığı Kayıp Sancak romanı da bunlardan biridir. Yazar, özgün bir bakış açısıyla Millî Mücadele döneminde Güney cephesinde yaşananlara dikkat çeker. Adana’nın düşman işgalinden kurtuluşuna ithafen yazılan romanda Adana halkının Millî Mücadele’nin kazanılmasında gösterdiği kahramanlık ve mücadele gözler önüne serilir. Romanın olay örgüsü, 31 Ekim 1918 tarihinde Mustafa Kemal’in Adana’ya gelişiyle başlar ve 5 Ocak 1922 tarihinde Adana’nın düşman işgalinden kurtuluşunun kutlama gösterileriyle son bulur. Bu zaman aralığında yaşananlar bir tarihî süreç şeklinde aktarılır. Romanda Millî Mücadele döneminde Mustafa Kemal tarafından Adana’nın işgalden kurtarılması amacıyla görevlendirilen başkişi Tekelioğlu Sinan’ın ve çevresindekilerin verdiği direniş hareketi anlatılır. Bu çalışma boyunca metin merkezli bir yaklaşımla Kayıp Sancak romanı yapı ve izlek açısından tüm yönleriyle incelenecektir.
Construcción y validación de un instrumento para evaluar la comprensión global lectora en estudiantes de tercero de primaria
Authors: Gaytan-Lugo Laura , Montesinos-López Osval , Alcaraz-Valencia Pablo , Fernández-Robles José
Published: October 2022

En México existe un problema en relación con la comprensión global lectora, lo cual se ha evidenciado en evaluaciones nacionales e internacionales. Sin embargo, existe un desacuerdo sobre los instrumentos utilizados para evaluar las habilidades de comprensión lectora. El objetivo de este trabajo es diseñar y validar un instrumento para evaluar la comprensión global lectora de estudiantes de tercer grado primaria. Con el uso del Análisis Factorial Confirmatorio (CFA) se confirmó un instrumento de 30 ítems y tres factores: ideas principales, inferencias y contextualización del concepto; que fue aplicado a 803 estudiantes. La evidencia demuestra que el mismo constructo es apropiado para diferentes variables contextuales (género, turnos y estatus). Los resultados del CFA ofrecen una solución satisfactoria en la estructura factorial de las escalas y en los niveles de consistencia interna.
Economic valuation of the environmental services of the Coata river basin, Puno-Peru
Authors: Quispe-Mamani Julio , Quispe-Mamani Felix , Roque-Guizada Cesar , Yapuchura-Saico Cristobal , Catachura-Vilca Alberto
Published: October 2022

The objective of the research was to economically value the environmental services of the Coata river watershed; Likewise, determine the willingness to pay for the improvement of environmental services and identify the socio-economic variables that determine the willingness to pay. The contingent valuation method and the binomial logit econometric model were applied, with a sample of 369 households living around the basin, for this the primary source data collection technique was used and the survey on the population was used as an instrument. that resides in the basin, using the statistical packages SPSS 25.0 and Stata 16.0 for the estimation and contrast of hypotheses. It was determined that the economic value of the DAP amounts to 4.88 soles per month, thus evidencing the existence of full willingness to pay by the families that live in the vicinity of the river basin. Finally, the DAP is explained by age in 2.77%, education in 3.1%, frequency of use of the environmental service in 2.3% and distance to the river in 2.3%.
Quizizz Application and understanding texts in English texts with the content of “Aprendo en Casa” Educational Platform
Authors: Laura Kevin , Morales Katherine , Clavitea Mery , Aza Patty
Published: October 2022

The objective of this research was to determine the results of the level of understanding texts in English with the content of “Aprendo en Casa” Educational Platform in second grade students at a Public School in Tacna by using Quizizz, 2020. The type of research that was used is experimental and the form was pre-experimental, the research method is hypothetico-deductive. The procedure for obtaining the data was through the application of pre and post-tests. The results indicate that after the post-test, 68.75% of students reached an outstanding level of achievement, 31.25% are at the expected level of achievement, 0% are at the process level, and at the beginning level. From the results obtained, it can be stated that the students from second grade managed to improve their level of understanding of English texts with the content of “Aprendo en Casa” Educational Platform through Quizizz.
Iron deficiency anemia and its relationship with academic performance in university students
Authors: Quispe Haydee , Castillo Eveling
Published: October 2022

The objective was to know the level of iron deficiency anemia and its relationship that it exerts on the low academic performance of the students at the Professional School of Medical Technology of the Andean University Néstor Cáceres Velásquez de Puno-Peru (2019). The research was quantitative and descriptive, correlational, cross-sectional. The sample consisted of 53 students (women), who were from the I, II, III and IV semesters. To obtain data, the hemoglobin value of the students was determined, and a validated survey was applied to them to know their academic performance. The results showed that there are low percentages of students with iron deficiency anemia. The relationship, according to Spearman Rho, indicates that there is a moderate association between iron deficiency anemia and academic performance.
Discipline (and reversibility) in the training space of school football: a case study
Authors: Merino Abel
Published: October 2022

Sports initiation takes place at a crossroads of sports, pedagogical and psychological interests. The monitoring of school sports requires the construction of a training discipline that underlines the promoted values in which the school-age child is formed. This study is interested in understanding the coordinates in which discipline is established in football, because it is one of the most important school sports, and the implications it has for the young athlete. A participant observation research design is used, in which 10 under 8 football teams participate during two school courses. Five qualitative categories emerge on the results: respect for an authority, commitment to an activity, preparatory routines, fissure in peer learning and behavior modeling. In the categories there are divergences between the coercive leadership of some coaches and the learning that schoolchildren build in their horizontal interaction. Families are an indispensable figure for the consolidation of the preparatory routines of the activity. The study concludes with the invitation to a reflection that converges in the educational interests of sports activity, whose purpose is to enhance its formative value and establish internal coherence.
Mediation in the accompaniment of students and parents in a digital context
Authors: Chávez Harol , Torres José , Cadenillas Violeta
Published: October 2022

In this research, the review of scientific articles on mediation in virtual teaching in situations of new educational experience was analyzed through a systematic study of specialized literature related to mediation in the accompaniment of students and parents in a digital context. The research design used is qualitative through documentary analysis. Specialized references and documents were handled in different types of data platforms and search equations. The study focused on the mediation category and four emerging subcategories: Mediation as a pedagogical method, a mediation tool for teaching, digital families and the mediator in the educational process, a comparison of exploration topics was made between mediation for teaching and shared responsibilities in learning. By way of conclusion, we can mention that the mediation was a means of pedagogical accompaniment for the students and their families.
Free pedagogies and emotional self-regulation: anti-authoritarian notes on education
Authors: Ponce-León Juan José
Published: October 2022

This article aimed to study the relationship between emotional self-regulation and free pedagogies. To do this, an extensive literature review was presented and a critical theoretical debate was raised about the limits of traditional education and its negative impact on children's mental health. The results show that, on the one hand, emotional self-regulation is a good predictor and protective factor against psychopathologies, and, on the other hand, that alternative education shows clinically significant impacts on the development of emotional self-regulation and, consequently, higher rates of satisfaction with life, proactive behaviors and fewer antisocial behaviors. In addition, traditional education shows a low level of socio-affective development in childhood.
Violencia escolar y mediación pedagógica en estudiantes de educación básica
Authors: Herrera Olga , Frausto Mireya
Published: October 2022

La violencia escolar es un tema muy complejo e interesante, debido a que ha permeado a la sociedad a través de la historia de la escolaridad. Se diseñó una estrategia para prevenir futuros desencuentros en los niños y niñas del grado quinto del colegio Marco Antonio Franco Rodríguez de Villavicencio, Colombia. Para la investigación se utilizó una metodología de tipo mixta, cualitativo y cuantitativo, se recolectó la información a través de una entrevista y una encuesta dirigidas a los estudiantes, mostrando como resultados que la problemática que más se repite es la burla en clase, el robo de cosas y agresiones físicas en el salón. Se puede concluir que la mediación es una oportunidad de cambio sin que haya perdedores, e invita a fomentar el diálogo y la escucha.
Characteristics, behaviors, and teaching tools that promoted online learning among university students during COVID-19
Authors: Torres Gerardo
Published: October 2022

The purpose of this research was to identify the characteristics, behaviors, and teaching tools that, according to the students of a degree in human resources from western Mexico, promoted learning during online classes due to COVID-19. The research was qualitative, non-experimental, exploratory, and cross-sectional. An open-ended questionnaire was applied to 109 participants (78% women and 22% men; average age 22.6 years). As a result, the teaching staff that promotes learning is characterized by being explanatory, understanding, patient, dynamic and empathetic; In behavioral terms, he explains the topics, schedules practical activities, gives constant feedback, sets flexible tasks, and is available to the student when required. In addition, the most effective teaching tools were videos, slides, video calls, virtual classrooms, and digital repositories.
Eficacia escolar en entornos urbano-marginados. Caso de una escuela primaria en Monterrey, México
Authors: Duarte José , Valenti Giovanna , Megchún Rodrigo
Published: October 2022

Este artículo indaga cómo la gestión institucional, el involucramiento docente y familiar se amalgaman para el logro escolar sostenido. La investigación se desarrolló en una escuela pública en el norte de México. Los estudiantes de esta institución, -localizada en una comunidad marginada y violenta-, obtuvieron durante tres años, puntajes superiores a la media nacional en pruebas que miden conocimientos en español, matemáticas y ciencias. Mediante un estudio de caso cualitativo que empleó la microsociología organizacional y el interaccionismo simbólico, encontramos que la gestión institucional está basada en sistemas organizacionales, el liderazgo es compartido y basado en la confianza; los docentes cuentan con altas competencias académicas y pedagógicas, utilizan estrategias innovadoras lúdicas, mantienen preocupación por mantener altos estándares académicos; las relaciones interpersonales son cercanas; las familias apoyan y participan en la escuela de forma consistente. Se concluye que es posible lograr la eficacia educativa cuando el contexto no es visto como limitante, sino como potenciador de aprendizajes, cuando hay organización, integración, compromiso, arraigo y cuando la comunidad educativa en su conjunto considera que la educación tiene potencial para la transformación social.
Sexual abuse of girls in Oaxaca: legal or cultural problem?
Authors: Fernández-Tapia Joselito
Published: October 2022

The article analyzed the problem of child sexual violence in the state of Oaxaca, Mexico. The methodology was qualitative based on analysis of documents (empirical studies, legislation and hemerography) and complemented with descriptive statistics. It is found that: legislation has been harmonized with national and international law, legal and applicability vacancies persist, bureaucratic processes, access to justice for victims, impunity and the absence of real statistics; the highest incidence is in the house and the school, being the principal aggressors of the family and teachers. The legal advance is the most significant, yet it does not recover the cultural diversity of the State. It is concluded that, in addition to a legal and cultural problem, constituting systemic, institutional and symbolic violence.
Inclusive education. How are we?
Authors: Montoya-González Ana
Published: October 2022

In this article we sought to summarize the entire process that children with special educational needs have gone through, starting with the historical journey to be recognized as subjects of rights, the process that has been carried out to integrate them into the classroom in class having consider the policies regarding the issue and finally, the difficulties that continue to arise with children with disabilities within the Colombian educational system. The review was carried out by means of the snowball method, in which one author referred us to another who could continue to contribute to the subject. The results show the characterization of the needs of the vulnerable population with differential disability in terms of respecting the fundamental and universal rights of education to the target population in question, strengthening concepts on issues of functional diversity, based on the implementation of a solid strategy and supported by universal education for the necessary accessibility for the population with varied disabilities.
Educación inclusiva. ¿Cómo estamos?
Authors: Montoya-González Ana
Published: October 2022

En el presente artículo se buscó resumir todo el proceso que han pasado los niños con necesidades educativas especiales, comenzando por el recorrido histórico para ser reconocidos como sujetos de derechos, el proceso que se ha llevado a cabo para integrarlo al aula en clase teniendo en cuenta las políticas con respecto al tema y finalmente, las dificultades que se siguen presentando con los niños en situación de discapacidad dentro del sistema educativo colombiano. La revisión se llevó a cabo, por medio del método de bola de nieve, en el cual un autor nos referenciaba a otro que podía seguir aportándonos en el tema. Los resultados evidencian la caracterización de las necesidades de la población vulnerable con discapacidad diferencial en función de respetar los derechos fundamentales y universales de la educación a la población objetivo en mención, fortaleciendo conceptos en temas de diversidad funcional, fundamentado en la implementación de una estrategia sólida y sustentada de enseñanza universal para la accesibilidad necesaria para la población con discapacidad variada.
Evaluation of the teacher profile based on the attributes of teaching performance
Authors: Flores Norma , Castelán Vianey , Zamora Mónica
Published: October 2022

The purpose of this research was to determine if the levels of teaching performance allow measuring the institutional profile based on a competency approach, as well as knowing its attributes and at what level teachers apply it: theoretically or practically. For this purpose, quantitative, cross-sectional, and correlational research was carried based on the application of two Likert-type questionnaires, obtaining these results: identification of attributes of the institutional teaching profile: mediator, planner, cultural agent, and promoter. It was distinguished that the self-evaluations measured the theoretical application of the teaching profile and the praxis from the evaluations, confirming that both are necessary to achieve the desired teaching profile. Also, the study hypothesis was verified by corroborating that the levels of teaching performance allow measuring the level of institutional teaching profile. In conclusion, the study showed that the teaching profile was satisfactory in the French Bachelor context because the teachers applied the four attributes on a scale from 80 to 89.
Reflections on MOOC supported by emerging technologies from the science, technology and society perspective
Authors: Atiaja Lourdes , García-Martínez Andrés
Published: October 2022

The dynamics of science and technology are the primary elements of the sustainable development of society in all areas. In the educational context, they have given rise to new forms of flexible, open and free or low-cost learning, such as MOOC (Massive Open Online Courses) that, supported by emerging technologies, have a social effect and contribute to the democratization of knowledge. In this sense, the main objective of this work is to identify the implications (limitations and scope) of MOOCs for the development of an inclusive education supported by emerging technologies and their impact on society, taking into account the main factors that generate it and develop, from the STS (Science, Technology and Society) vision, through the application of historical-logical, analysis and synthesis methods and finally generalization-abstraction, taking primary and secondary bibliographic sources as important, with the purpose that the institutions educational institutions incorporate MOOC as an alternative for permanent training and updating of knowledge that the knowledge society demands so much.
Tecnología de red definida por software para el aprendizaje en grupos de investigación y educación
Authors: Silva José
Published: October 2022

La red definida por software (SDN) es un paradigma de red emergente y programable que cambia la forma en que se diseñan y administran las redes al introducir una abstracción que desacopla el control del plano de datos. Esta tecnología ha generado un gran interés tanto en la industria como en la academia. SDN tiene como objetivo simplificar la gestión de la red al tiempo que permite a los estudiantes, docentes e investigadores experimentar con protocolos en las redes que se usan a diario. Además, ha llevado al surgimiento de nuevas tendencias en los sistemas educativos, especialmente el sector universitario, en administración de sistemas y redes computacionales. Debido a la poca difusión de las SDN y la alta proyección que tiene actualmente esta tecnología, es fundamental que sean las entidades educativas universitarias las que incursionen en esta temática. Es por ello que, el presente ensayo es una síntesis donde se aborda la importancia de aplicar las SDN para fines educativos y en el contexto de grupos de investigación académica.
Development of scientific inquiry, from an authentic task with the petroglyph of the Wak’a of Suyo
Authors: Taipe Franklin , Serna Juan , Quispe Cipriano , Quispe Wilfredo , Condori Isabel
Published: October 2022

The purpose was to develop the competence investigates through scientific methods with content analysis, to build new knowledge in the area of science in three groups of teachers with the task of authenticating “possible explanations of the message of the Wa’ka de Suyo petroglyph”. Using basic research teaching-learning methodology. Developing in three stages: initiation with the field visit for motivation, measurements and interviews; development with the scientific inquiry of content analysis; completion to expose and discuss the validation of your guesses. The result of the astronomical aspect explains the analogy of the circles with binary star systems, the meteorological aspect explains the similarity with the cloud-earth and earth-cloud rays and with the ascending rays, of the biological aspect of conjecture reproductive cells does not reach similar findings. The development of the competence was achieved from the inquiry by content analysis motivated by the authentic task.
Understand teacher resilience. A systematic look
Authors: Tenorio-Vilchez Carmen , Sucari Wilson
Published: October 2022

The objective was to carry out a systematic review on the concept of teacher resilience, the characteristics of resilient teachers, and the search for the main strategies that can serve to improve teacher resilience. The information management was done in an extended way and without the segment of years publication of different scientific articles. As a result, the concept of resilience is redefined as a capacity, process, and ability that encompass the emotional, motivational, and social dimensions of the teacher. Among the characteristics of a resilient teacher, humor, confidence, self-esteem, problem-solving, optimism, and interest in technology stand out. The strategies that serve to improve resilience derive from the psychological, pedagogical, and linguistic-sociological.
Analysis of the deforestation of the Peruvian Amazon: Madre de Dios
Authors: Luque-Ramos Lourdes
Published: October 2022

The objective of this article was to systematize the evidence of deforestation and determine the main factors of forest loss in the department of Madre de Dios, Peru. A search was carried out for scientific research related to "deforestation", "Peruvian Amazon deforestation", deforestation Madre de Dios". Scientific articles published in a database of indexed journals were analyzed. A descriptive, non-experimental study design was chosen. For data collection, the document analysis technique was applied. Based on the evidence, it is concluded that the areas of most significant deforestation are concentrated in the southern Amazon, mainly in Madre de Dios. In addition, the main factors of forest loss are illegal mining and mostly illegal agricultural activities; within these two activities, illegal mining is the cause of the highest percentage. Negative aspects such as the loss of biodiversity also prevail, contributing to climate change.
Isolasi Fungi Tanah Kabupaten Situbondo serta Skrining Aktivitas Antibakteri Terhadap Pseudomonas Aeruginosa
Authors: Pamungkas Fawwas Batio Putra , Triatmoko Bawon , Nugraha Ari Satia
Published: October 2022

Resistensi agen antibakteri terhadap bakteri menjadi perhatian serius. Pencarian senyawa antibakteribaru dari tanaman obat dapat mengakibatkan eksploitasi bahan alam secara berlebihan. Oleh karena itu pencarian sumber alternatif baru perlu dilakukan. Penelitian ini bertujuan untuk mencari agen antibakteri baru yang berasal dari fungi tanah yang diisolasi dari tanah rawa di kawasan Pantai Pasir Putih Kabupaten Situbondo dalam menghambat Pseudomonas aeruginosa (P. aeruginosa). Isolasi dilakukan dengan media Potato Dextrose Agar (PDA) yang dilarutkan dalam air laut. Hasil dari isolasi didapatkan 5 isolat fungi. Fungi dengan kode IS-STBIII- 4 dan IS-STB-III-5 memiliki potensi dalam menghambat pertumbuhan bakteri dengan uji antagonis. Fungi tanah potensial dilakukan fermentasi selama 14 hari dan dilakukan ekstraksi dengan pelarut etil asetat. Hasil ekstraksi dilarutkan dalam pelarut DMSO 10% dengan seri konsentrasi 1000 μg/mL, 2000 μg/mL, 4000 μg/mL, 6000 μg/mL, 8000 μg/mL yang akan digunakan sebagai larutan uji aktivitas antibakteri dengan metode difusi cakram. Hasil uji aktivitas ekstrak menunjukan hasil yang berbanding lurus dengan konsentrasi ekstrak. Hasil analisis dan profi ling senyawa dalam ekstrak dengan instrumen Kromatografi Cepat Kinerja Tinggi (KCKT) menunjukan bahwa ekstrak mengandung alkaloid yang kemudian diisolasi dan diidentifi kasi dengan KCKT.
Formulation and the Antibacterial Activity of Mulberry leaves extract Gel (Morus alba L.) against Staphyococcus aureus
Authors: Pamuladiman Akbar Rino , Widiyastuti Lina
Published: October 2022

Mulberry leaves (Morus alba L.) contain quercetin, a ﬂavonoid compound with antibacterial activity against Staphylococcus aureus. For convenience, dosage accuracy, and hygiene, a gel formulation with a mixture of carbopol and propylene glycol is required. This study aimed to determine the right concentration of carbopol and propylene glycol to obtain a gel with good physical properties and antibacterial activity on Staphylococcus aureus. Mulberry leaf extract was obtained by maceration method. A factorial design method was used to optimize carbopol and propylene glycol concentrations. The parameters of gel physical properties were the viscosity, spreadability, adhesion, and pH test. The optimal area was determined by creating a contour plot of the parameters test result. Validation of the optimum formula was by comparing the prediction result to the actual research result. The data were analyzed using SPSS with a 95% conﬁdence level. The results showed that the concentration of carbopol and propylene glycol was 1.04% and 7.85%, 1832.42 ± 62.48 cP viscosity, 5.96 ± 0.08 cm spreadability, 64.63 ± 0.97 seconds of adhesion, and pH 5.26 ± 0.03. The antibacterial test showed an inhibitory power with 28.67 ± 0.76 mm. From the teat result, it can be concluded that the gel had antibacterial activity and good physical properties.
Analysis of Pancreatic Lipase Inhibitor Activity of Chlorogenic Acid Derivatives in Green Coffee Beans as Antiobesity using In Silico
Authors: Faridah Faridah , Sumaryono Wahono , Simanjuntak Partomuan , Triwibowo Rizki Riyadi
Published: October 2022

Obesity or overweight is defi ned as the accumulation of abnormal or excessive fat in adipose tissue whichcan damage health.Several plants have been used empirically as antiobesity.This study aims to obtain candidate antiobesity compounds that act as pancreatic lipase enzyme inhibitors, fi nd some amino acids that involved on the active site of the receptors and modelling the interactions of these active compounds at antiobesity receptors.The study start with internal validation of the receptors used (4DOQ), then carried out the docking process for the native ligand, comparison compound (Orlistat) and each test compound with the same receptor. The softwares used are PLANTS, YASARA, ChemSketch, and Pymol. The results of the 4DOQ receptor validation have an RMSD value of 1.7097 Ǻ. The results of the docking score for orlistat (-65.3258), and 4 active compounds namely chlorogenic acid (-69,3009), 5-O-caff eoylquinat acid (-70.6911), 4,5-O-dicaff eoilkuinic acid (-85 , 3375), 5-Op-coumaroilkuinic acid (-67,1886). Amino acids that play a role in the affi nity on the active side of the ligand bond with the pancreatic lipase receptor are THR21 (Threonine), ASN84 (Asparagine), GLY19 (Glycine), GLN156 (Glutamine), ALA85 (Alanine), ILE63 (Isoleucine), ARG62 (Arginine) . The conclusion of this study there are 4 chemical compounds in green coff ee beans that are active as antiobesity with the mechanism of action of the pancreatic lipase enzyme inhibitor, namely chlorogenic acid, 5-O-caff eoylquinic acid, 4,5-O-diphoeilquinic acid, 5-op-coumaroilquinic acid.
Efek Penurunan Kadar Glukosa Darah Rebusan Asparagus (Asparagus offi cinalis L.) Pada Mencit yang Diinduksi Aloksan
Authors: Dewi Rika Sari , Rahayu Lestari , Sandhiutami Ni Made Dwi , Khairani Sondang , Atika Isti
Published: October 2022

Diabetes mellitus ditandai dengan hiperglikemia yang merupakan kondisi tingginya glukosa darah.Di Indonesia, banyak ragam jenis tanaman obat yang digunakan sebagai pengobatan antidiabetes. Tanamanobat telah dikenal memiliki efek samping yang relatif lebih sedikit dibandingkan dengan obat berbasis kimia.Asparagus telah dilaporkan memiliki kandungan senyawa fl avonoid dan saponin yang dapat dimanfaatkansebagai antidiabetes. Tujuan dalam penelitian ini adalah untuk mendapatkan informasi terkait efek rebusanasparagus terhadap kadar glukosa darah pada mencit yang diinduksi dengan aloksan. Penelitian ini menggunakan 30 ekor mencit jantan galur DDY, yang dikelompokkan menjadi 6 kelompok, dan tiap kelompok terdiri atas 5 ekor mencit. 6 kelompok ini terdiri atas : kontrol normal, kontrol negatif, kontrol positif (Akarbose), rebusan asparagus dengan dosis 280, 560, dan 840 mg/kgBB selama 14 hari. Kadar glukosa darah diamati pada hari ke-0, 8, 15, dan 22. Hasil menunjukkan bahwa injeksi aloksan dapat meningkatkan kadar glukosa darah. Hasil lainnya menunjukkan bahwa rebusan asparagus dengan dosis 280, 560, dan 840 mg/kgBB dapat menurunkan kadar glukosa darah dan efek terlihat pada kelompok uji dosis 560 dan 840 mg/kgBB memiliki hasil tidak berbeda bermakna dengan kelompok kontrol positif (Akarbose).
Pengaruh Disintegran dan Cara Pencampuran Terhadap Sifat Fisika Kimia Telmisartan
Authors: Ratih Hestiary , Alatas Fikri , Pamudji Jessie Sofia , Soewandhi Sundani Nurono
Published: October 2022

Telmisartan (TMS) mempunyai struktur yang padat dan saling mengunci antar unit kristal.Hal ini mengakibatkan zat mempunyai gaya elektrostatik tinggi sehingga ketika dikompresi menjaditablet, TMS mengalami sintering. Salah satu upaya untuk mengatasi sintering pada tablet TMSadalah dengan menambahkan disintegran. Disintegran yang digunakan adalah berasal dari golonganpati: Starch 1500® (S1500) dan sodium starch glikolat (SSG) serta golongan selulosa mikrokristalinselulosa (MCC) dan croscarmellose sodium (CCS). Tujuan penelitian ini adalah melihat pengaruhbeberapa disintegran terhadap sifat fi sikokimia TMS dengan berbagai perlakuan. TMS divariasikandengan masing-masing disintegran dengan perbandingan 1:9% b/b. Perlakuan terhadap campuranbiner TMS dengan berbagai disintegran meliputi campuran fi sik, campuran digiling, campuran yangdikompresi dan campuran dikompresi yang dihancurkan. Karakterisasi dan evaluasi meliputi pengujianPXRD, SEM dan uji disolusi. Karakterisasi PXRD dan SEM pada berbagai perlakuan menunjukkanadanya pengaruh sifat fi sikokimia terhadap campuran biner TMS dengan berbagai macam disintegran.Kombinasi TMS:CCS dengan perbandingan (1:9) menghasilkan laju disolusi tertinggi pada semuaperlakuan Perlakuan campuran yang digiling memberikan disolusi tertinggi dengan DP60 menit yaitusekitar 55,86±2,47%. Penambahan disintegran pada TMS dengan berbagai perlakuan dapat mengurangisintering tetapi masih belum cukup untuk memenuhi persyaratan disolusi TMS yaitu dalam waktu 30menit terdisolusi dalam media dapar fosfat pH 7,5 dengan Q>75%.
Uji Potensi Antijerawat Secara In Vitro dan Ex Vivo dari Ekstrak Etanol Herba Alfalfa (Medicago sativa L.)
Authors: Safitri Erika Indah , Fithria Risha Fillah , Saputro Eko Wahyu , Wijaya Danang Yogo
Published: October 2022

Bakteri Propionibacterium acnes merupakan salah satu bakteri penyebab jerawat. Permasalahan jerawat dapat dikendalikan dengan tanaman herbal yaitu herba alfalfa. Kandungan flavonoid dalam herba alfalfa berkhasiat sebagai antijerawat. Penelitian ini bertujuan untuk menetapkan kadar flavonoid total serta pengujian potensi ekstrak etanol herba alfalfa (EEHA) sebagai antijerawat secara in vitro dan ex vivo yang diinduksi bakteri Propionibacterium acnes. Penetapan kadar flavonoid total menggunakan metode spektrofotometer dengan pembanding kuersetin. Pengujian ekstrak etanol herba alfalfa secara in vitro menggunakan metode difusi cakram pada seri konsentrasi 40%, 50%, 60%, 70%, dan 80%. Sementara itu, pengujian ekstrak secara ex vivo menggunakan kelinci yang diinduksi bakteri Propionibacterium acnes secara intradermal pada 3 konsentrasi optimal dari uji in vitro (50%, 60%, dan70%). Parameter pengujian ini berupa diameter daerah hambat dan penurunan diameter eritema. Ekstrak etanol herba alfalfa mengandung flavonoid total sebesar 2,323 mgQE/g. Seluruh konsentrasi ekstrak etanol herba alfalfa memiliki aktivitas antibakteri terhadap P. acnes dengan rata rata diameter daerah hambat iradikal masing masing 14,60 mm; 14,89 mm; 15,56 mm; 16,52 mm; dan 18,59 mm. Persentase rata-rata  penurunan  diameter  eritema secara ex vivo pada ekstrak etanol herba alfalfa (50%, 60% dan 70%) secara berturut-turut sebesar 48,70%; 48,26% dan 54,09%.
Activity Of Ethanol Extracts 70%, Extract Nanoparticles And Nanoparticles Tablet Of Okra Fruit Extract(Abelmoschus esculentus (L) Moench.) As Anti-Dislipidemia In Rats Feeded On High Fat Diet
Authors: Zaidan Sarah , Rahmat Deni , Djamil Ratna , Saputri Nadya Vresya
Published: October 2022

Dyslipidemia is a condition caused by disruption of lipid metabolism due to the interaction of genetic factors and environmental factors. There is strong evidence of an association between LDL cholesterol and cardiovascular events based on clinical outcome studies, so LDL cholesterol is the main target in the management of dyslipidemia. In addition to using synthetic drugs, dyslipidemia can be treated by consuming natural ingredients, one of which is okra (Abelmoschus esculentus (L) Moench). The form of nanoparticles and nanoparticle tablets of okra fruit extract is an effort to increase antidyslipidemic activity and to make it easier to use. This study aims to obtain nanoparticle extracts and nanoparticle tablets of okra fruit extract which have antidyslipidemic activity in vivo against mice given the High Fat Diet (HFD). The research used 24 rats divided into 6 treatment groups, namely group I as normal control, group II as positive control using simvastatin as the control control, group III as a negative control, group IV as a control treatment of ethanol extract 70% okra fruit, group V as a control treatment of okra fruit extract nanoparticles, and group VI as a treatment of okra fruit extract nanoparticles tablets. All test substances are given for 14 days. Blood sampling was carried out on days 0, 14, and 28, with the parameters measured were lipid profiles including total cholesterol (KT), LDL, Triglycerides (TG) and HDL. 70% ethanol extract, extract nanoparticles, and okra fruit extract nanoparticle tablets can decrease KT levels by 33.14%, 46.31%, 45.42%, decrease TG levels by 39.46%, 43.56%, 41, 62%, decrease LDL levels by 45.22%, 68.76%, 59.94%, and can increase HDL levels by 103.80%, 119.20%, 114.39%. Based on the lipid profile of mice given HFD, 70% ethanol extract, nanoparticles, and okra fruit extract nanoparticle tablets had antidyslipidemic activity.
Analisis Dampak Program Pengelolaan Penyakit Kronis (Prolanis) Dalam Meningkatkan Outcome Klinis Pasien Diabetes Melitus Tipe 2 Di Puskesmas Jakarta, Indonesia
Authors: Manninda Reise , Anggriani Yusi , Sari Astrid Kartika
Published: October 2022

Prolanis adalah Program Manajemen Penyakit Kronis di bawah Jaminan Kesehatan Nasional Indonesia untuk mempromosikan dan mencegah penyakit kronis. Kegiatan utama program Prolanis adalah pengendalian dan konseling penyakit, pendidikan terjadwal, olahraga terjadwal, pengingat jadwal pasien, dan kunjungan rumah. Tujuan dari penelitian ini adalah untuk mengevaluasi dampak prolanis terhadap hasil klinis pada pasien Diabetes Melitus tipe 2 (DM). Penelitian secara observasional dan retrospektif. Data rekam medis diperoleh dari selama periode tahun 2015. Sebanyak 426 pasien dari lima Puskesmas di Jakarta dipilih secara  random sampling dan dibagi menjadi kelompok prolanis dan non-prolanis. Indikatornya adalah perbedaan hasil klinis antara pasien prolanis dan non-prolanis dianalisis menggunakan uji Mann-Whitney; korelasi kepatuhan dengan hasil klinis dianalisis menggunakan uji Chi-Square. Hasilnya menunjukkan bahwa pasien prolanis memiliki peningkatan yang signifikan dalam Glukosa Darah Puasa (FBG) dibandingkan dengan pasien non-prolanis (P <0,05). Kepatuhan pasien prolanis menunjukkan peningkatan yang signifikan pada FBG (124 pasien-58,2%). Pasien dengan ketidakpatuhan memiliki peningkatan FBG yang lebih rendah, peningkatan diamati hanya pada 16 pasien (7,5%) dan 60 pasien (28,17%) adalah FBG yang memburuk. Prolanis adalah program yang efektif untuk meningkatkan hasil klinis pasien DM.
Profil Fitokimia Simplisia dan Ekstrak Etanol Daun Kedondong Pagar (Lannea coromandelica (Houtt.) Merr.) sebagai Tanaman Obat
Authors: Safriana Safriana , Andilala Andilala , Fatimah Cut , Samrani Samrani
Published: October 2022

Lannea coromandelica (Houtt.) Merr., atau dikenal sebagai Kedongdong Pagar di Indonesia, famili Anacardiaceae, Daun Kedongdong Pagar telah dibuktikan oleh warga Desa Samakurok, Kecamatan Tanah Jambo Aye, Aceh Utara, NAD, untuk menurunkan kadar glukosa darah dengan mengkonsumsi air rebusan daun kedongdong pagar. Tujuan penelitian ini untuk mengetahui golongan senyawa kimia yang terkandung dalam simplisia dan ekstrak etanol daun kedongdong pagar dari hasil penapisan fitokimia. Hasil penapisan fitokimia menunjukkan bahwa senyawa kimia yang terkandung dalam simplisia dan ekstrak daun kedongdong pagar adalah flavonoid, saponin, glikosida, tanin dan steroid/triterpenoid. Berdasarkan penelitian yang telah dilakukan, daun kedongdong pagar memiliki potensi yang besar untuk diteliti dan dikembangkan lebih lanjut menjadi salah satu sumber tanaman obat di Indonesia.
Bauran Pemasaran Hyaluronic Acid untuk Pengobatan Penyakit Ulcerative colitis
Authors: Rani Atika , Widyastuti Sri , Sumaryono Wahono , Lesmana Henky
Published: October 2022

Ulcerative colitis (UC) is a chronic inflammatory condition in the proximal colon which is generally characterized by abdominal pain, diarrhea, fever and weight loss. Oral medication is usually used in the long term about 6 months or even for life. Study results show that hyaluronic acid (HA) has an important role in colon inflammatory diseases. HA is given by enema form for 28 days of therapy. This study was conducted to determine the doctors interest in HA enema products as an alternative therapy for UC disease treatment. This study is a qualitative exploratory descriptive study by in depth interview to Consultant Internist Gastroenterohepatology (KGEH) and Internist Specialist who treat UC disease patients which focuses on marketing mix, specifically product, price and promotion. The results showed that HA enema products could be accepted as an alternative choice for treatment therapy in UC patients with low to moderate severity in adolescent patients to the elderly.
Pengaruh Website Quality dan Website Brand terhadap Minat Beli Online dengan Kepercayaan sebagai Variabel Mediasi (Survei pada Konsumen Shopee Kota Padang)
Authors: Annisa Fitrah Ramialis  , Eri Besra
Published: October 2022

Penelitian ini bertujuan untuk menganalisis pengaruh website quality dan website brand terhadap minat beli online dengan kepercayaan sebagai variabel mediasi dari survei yang dilakukan pada konsumen Shopee di kota Padang. Variabel dalam penelitian ini website quality, website brand, kepercayaan konsumen, dan minat beli online. Respondennya adalah masyarakat kota Padang yang pernah mengunjungi (melihat-lihat) atau bertransaksi online menggunakan aplikasi Shopee minimal satu kali transaksi. Metode pengambilan sampel yang digunakan adalah metode purposive sampling, dengan jumlah sampel penelitian ini adalah sebanyak 135 responden. Pengolahan dan analisis data dilakukan dengan menggunakan SmartPLS. Hasil penelitian yang didapat menunjukkan bahwa website quality, website brand, dan kepercayaan berpengaruh positif dan signifikan terhadap minat beli online, website quality dan website brand berpengaruh positif dan signifikan terhadap kepercayaan dan kepercayaan berperan sebagai mediasi parsial antara website quality dan website brand terhadap minat beli online pada konsumen Shopee.
Strategi Pengembangan Batching Plant di Sumatera Barat (Studi Kasus PT. ABC)
Authors: Hayattul Riski
Published: October 2022

Persaingan dunia usaha semakin meningkat, perusahaan dituntut untuk dapat bertahan dan bersaing dengan perusahaan lain yang sejenis demi kemajuan dan eksistensi perusahaan. Perusahaan ditantang untuk dapat beradaptasi dengan lingkungan sekitar, atau dengan kata lain setiap perusahaan harus mampu mengikuti perubahan yang terjadi, baik perubahan dari internal maupun dari eksternal perusahaan. PT ABC adalah salah satu pelaku usaha batching plant di kota Padang. Bisnis dimulai pada tahun 2016 dengan lini bisnis yang berfokus pada penjualan beton siap pakai. PT ABC perlu mengidentifikasi dan menganalisa tingkat persaingan bisnis yang semakin ketat. Tujuan dari penelitian ini adalah mengevaluasi strategi dan merekomendasikan alternatif strategi terbaik yang digunakan oleh PT ABC sesuai dengan kondisi lingkungan perusahaan. Tahap pencocokan menggunakan Matriks SWOT dan Matriks Eksternal Internal untuk mendapatkan alternatif strategi yang akhirnya menentukan keputusan strategi yang tepat. Hasil penelitian ini merekomendasikan agar PT ABC sebenarnya memiliki kekuatan internal dan peluang eksternal yang besar dalam rangka mengembangkan bisnis dan menghadapi tingkat persaingan dengan menggunakan Strategi Pengembangan Pasar dan Strategi Pengembangan Produk guna mencapai visi dan misi perusahaan
The Impact of Integrity, Professionalism, and Self-Efficacy of Auditors on Audit Quality
Authors: Ardillah Kenny
Published: October 2022

Audit quality is a finding of violations by the auditor in recording the client's financial statements. Audit quality is strongly influenced by the auditor as the party auditing the financial statements, so the auditor needs to follow and carry out his duties by the auditing standards that apply during the audit process. This investigation expects to analyze the impact of integrity, professionalism, and self-efficacy of auditors on audit quality. The populace in this investigation were all autonomous auditors who work in Public Accounting Firm which are enlisted with the Republic of Indonesia's Financial Audit institution. The sampling technique used in this study was simple random sampling. Data collection techniques in this study using library research and questionnaires. Hypothesis testing in this study uses multiple regression data analysis techniques using SPSS version 25.0. The results of this study indicate that integrity, professionalism, and self-efficacy have a positive effect on audit quality. The implications of this research are academic implications to determine the factors that can affect audit quality and can be used as material for developing research and knowledge, especially in the field of accounting related to audit quality and practical implications for developing further research in the auditing field.
A Finance Division Operational Risk Management System Design
Authors: Maria Ursula Vianna , Bramantyo Djohanputro
Published: October 2022

NFI is a national private company in Indonesian FMCG industry, headquartered in Jakarta which in 2021 carries the topic of simplification and digitalization of finance division's operations as the main topic. The process of simplification and digitization will make financial operational faster, but there are also many bad possibilities that can arise if NFI has not improved its risk management system because the current risk determination is still not good where it is only limited to writing down problems that have been resolved. Therefore, this qualitative research aims to create an Operational Risk Management System Design for the NFI Finance Division using the ISO 31000: 2018 guidelines which have 3 main elements, namely risk management principles, risk management pendekatan and risk management process. The risk management process consists of communication, determining the context, identifying risks, analyzing risks, evaluating risks, and planning for risk management. The data sources used are primary and secondary data with collection techniques in the form of interviews, observations, document studies, and group discussion forums and then analyzed using a combination of qualitative and quantitative approaches. Based on assessment that has been carried out, 30 operational risks were identified, 7 risks are high risk, 12 medium risk, 8 low risk, and 3 risks are very low risk. Therefore, it is necessary to have a risk management system that will help NFI in developing risk management plans.