bluuebunny/crossref_metadata_2025 huggingface dataset:
A model for estimating the influence of chlorine scattering at its emergency releases into the atmosphere at a potentially hazardous object in the city of Krasnoyarsk
Authors:   Main Directorate of EMERCOM of Russia for the Krasnoyarsk Territory, Khrulkevich A. L. , Grebnev Y. V. ,   Main Directorate of EMERCOM of Russia for the Krasnoyarsk Territory, Ovsyanik A. I. ,   Financial University under the Government of the Russian Federation; Academy of State Fire Service of EMERCOM of Russia
Published: December 2021

Introduction. The article considers the risk of occurrence and development of an emergency situation caused by the occurrence of a landscape fire and the transition of a fire to technological buildings with further depressurization of containers containing chlorine. One of the threats to the city of Krasnoyarsk is chemically hazardous facilities that have the task of providing life support to the population and are located in complete isolation. These objects do not have a road connection with the coastline, which makes it practically impossible to use forces and means designed to respond to operational events at these objects in a timely manner. Goals and objectives. The aim of the study was to simulate the conditions of chlorine scattering during its accidental releases into the atmosphere and to identify the dependencies of the scattering parameters on the technological features of the release, weather conditions, as well as the characteristics of the environment where the release occurs. Methods. To simulate an emergency situation at a water treatment plant, the method of simulation modeling using the TOXI+Risk software product was used, and the method of neural network forecasting using the Scikit-Learn library in the Python programming language was used. Results and discussion. The simulation results demonstrated the possibility of using neural network modeling to solve the problem of short-term forecasting of the areas of dispersion of a chemically dangerous substance (chlorine). The analytical method and the neural network method are compared. Proposals have been developed to reduce the potential risk of an emergency. Conclusions. The use of a neural network model makes it possible to increase the speed of calculating the concentrations of AHS at various points in space in comparison with the use of a traditional integral model, as well as to assess the potential danger of scattering AHS in the event of destruction of the tank in the presence of a terrain model. However, the considered neural network model can predict the concentration exclusively in the training ranges of weather conditions. The combination of neural network and integrated models makes it possible to solve the problems of industrial safety under any circumstances. Key words: emergency chemically hazardous substance, emergency, chlorine, risk, threat, simulation modeling, forecasting, neural network model, analytical model.
Mathematical basis of stochastic modeling multicomponent risks in security systems
Authors:   Russian Presidential Academy of National Economy and Public Administration, Prus M. Yu.
Published: December 2021

Introduction. It is shown that the development of methods for modeling multicomponent risks is a promising direction for improving information and analytical support for control in security systems. The purpose of the study is to develop new approaches to the study of natural, technogenic and anthropogenic risks based on stochastic modeling of the structure of multicomponent risks in socio-technical systems. Methods of stochastic modeling are based on a matrix representation of risk components, detailing the states of the protected object and the probabilistic characteristics of the functioning of security systems. Results and discussion. A method for analyzing multicomponent risks is presented, reflecting in-depth detailing of the states of the protected object and the probabilistic characteristics of the functioning of security systems. A stochastic model has been built that describes the structure of risk as a result of the interaction of two components, a multiplier and an accelerator, associated with various elements of the model, which, respectively, determine the possibility of occurrence of dangerous events, as well as the degree of vulnerability of protected objects. A connection is established between the indicators of expected losses in a certain territory with the presence of forces, means and systems of protection against the effects of hazardous factors and their current state. The procedures for determining the main parameters of the proposed stochastic model based on statistical and expert methods are discussed. A mathematical toolkit has been created for comparative analysis of the effectiveness of measures to reduce risks in socio-technical systems. The problem of multicriteria combinatorial optimization of planned costs and distribution of financial, material, technical and labor resources in territorial security systems is formulated. Conclusions. Methods for modeling multicomponent risks can be used to create effective algorithms for supporting risk-oriented management in security systems. Key words: stochastic modeling, multicomponent risk, socio-technical system, risk management, security system.
Justification of methods for calculating electrical loads life support systems for the affected population and rescue units during field deployment
Authors:   Academy of State Fire Service of EMERCOM of Russia, Sednev V. A.
Published: December 2021

Introduction. Over the past twenty years, the most severe natural and man-made disasters have occurred in various regions of the country and the world, as a result of which people were deprived of housing. The increase in the number, scale and duration of the consequences of emergencies related to the violation of the conditions of normal living of people requires the creation of temporary field accommodation points for the affected population, which create and serve rescue formations. At the same time, in the complex of tasks aimed at the life support of the population and rescue units in field temporary accommodation facilities, their electric power supply plays an important role. However, the established practice of calculating the electrical loads of stationary objects by methods based on data on separate electrical receivers makes it difficult to determine them for a field temporary location of people due to the lack of reliable information on its electrical receivers, which leads to significant errors in calculations, irrational composition of the electrical supply system and the use of its elements against the background of restrictions in the use of local energy resources and infrastructure facilities, which themselves may experience difficulties with reliable power supply due to the limited capacity of local power systems. The purpose of the study. Electric power supply and electric power safety of field temporary accommodation points of the affected population and rescue units, ensuring the required reliability of electric power supply, maximizing its efficiency in conditions of possible resource constraints and minimizing the influence of the uncertainty factor when planning power consumption. Research methods. The main provisions of the calculation of electrical loads, systems theory, set theory, probability theory and the apparatus of mathematical statistics. The results of the study. A methodology has been developed that allows to justify the power consumption of a temporary field accommodation facility for people, while the construction of its life support power supply system is carried out in accordance with the available consumers, taking into account their composition, area and other factors affecting the organization of the power supply system and the construction of consumers. Conclusion. The scientific and methodological approach to the choice of methods for calculating the electrical loads of the life support system of the affected population and rescue units during field deployment is substantiated, which also allows to resolve the contradiction between the need to organize the power supply of their life support and the lack of reasonable standards of power consumption of life support facilities and methods of their calculation. Key words: temporary field accommodation, life support, electric energy consumers, electric power supply, organization.
Actualization of problems of technical support management of territorial bodies of EMERCOM of Russia based on the questionnaire and expert survey
Authors:   Academy of State Fire Service of EMERCOM of Russia, Aristarkhov V. A. , Satin A. P. ,   Academy of State Fire Service of EMERCOM of Russia, Daines V.A. ,   Department of Strategic Planning and Organizational Work of EMERCOM of Russia, Matyushin A. V. ,   All-Russian Research Institute of Fire Protection of EMERCOM of Russia, Semikov V. L. ,   Academy of State Fire Service of EMERCOM of Russia
Published: December 2021

Introduction. The study of factors influencing the organization of technical support management of subdivisions of territorial bodies of the EMERCOM of Russia has been carried out. A questionnaire was developed, a selection was carried out and a survey was conducted of employees holding positions at various levels of the hierarchy of the technical support management system of the territorial bodies of the EMERCOM of Russia, starting from a separate unit and up to the central office of the EMERCOM of Russia. The ranking of factors affecting the organization of technical support using the method of expert survey is made. The most significant factors negatively affecting the organization of technical support have been identified. The problem of managing the technical support of divisions in modern conditions is actualized. Goals and objectives. The purpose of the study is to improve the management of technical support of the units of the EMERCOM of Russia by updating and scientific substantiation of factors that negatively affect the management processes. To achieve the goal, the tasks of selecting survey participants, experts, conducting a questionnaire and expert survey and processing the results were solved. Methods. In the course of the study, the questionnaire method and the method of expert assessments were used. Results and discussion. The most significant factors that negatively affect the process of managing the technical support of divisions have been identified. The relevance of the conducted research and its main directions, which are presented as the most significant factors, are substantiated. Conclusion. The results obtained in the course of the work can be used in the development of proposals for improving the management system of technical support units and determining promising areas of research in this area. Key words: technical support, management system, factors, experts, ranks, coordination, evaluation, technique.
Depth of extinguishing as a criterion for effectiveness of management of combat operations to extinguish a fire in residential buildings
Authors:   Academy of State Fire Service of EMERCOM of Russia, Zhuravlev N. M.
Published: December 2021

Introduction. The article substantiates the use of the depth of fire extinguishing by fire-fighting hoses for estimating the possibility of localization of fire in the management of combat operations in residential buildings. On the basis of the criterion in a generalized form a block-scheme of the generalized algorithm of the decision-making support of the fire extinguishing manager, which makes it possible to determine the possibility of localization of the fire by the available water fire-fighting hoses, is offered. A theoretical substantiation of the value of depth of fire extinguishing with direct fire-extinguishing jets in not-large squares of rooms and a functional dependence of the depth of extinguishing on the water pressure before the fire hose nozzle, which raises the calculation accuracy, is given. Goals and objectives. To evaluate the possibilities of localization of the fire by the available means and, as a whole, to increase the efficiency of fire-extinguishing management by the fire-division in the multi-story dwelling buildings. Increasing the calculation accuracy of the depth of fire extinguishing. Methods. Using the depth of fire extinguishing as an efficiency criterion in estimating the effectiveness of fire fighting with water fire-fighting units. The comparison of the actual value of the criterion with the required value determines the possibility of localization of the fire. Conclusions. The use of extinguishing depth as a criterion of effectiveness can serve as a basis for new methods and models to support the management decision-making of the fire extinguishing manager. The depth of fire extinguishing can be calculated as a function of the head before the nozzle of a fire-brigade can be used as a criterion of efficiency of the management of a fire-unit armed with water fire-brigade. Key words: fire, management, decision-making support, algorithm, efficiency criterion, depth of fire extinguishing.
Modern methods to reduce evaporation and ensure safety when storing petroleum products in tanks
Authors:   Ulyanovsk State Technical University, Kuzminskaya A. M. , Buzaeva M. V. ,   Ulyanovsk State Technical University, Ageeva O. V. ,   Academy of State Fire Service of EMERCOM of Russia
Published: December 2021

Introduction. With long-term storage of gasoline in large-capacity tanks, the problem associated with their volatility becomes urgent. Evaporation of petroleum products and gasoline leads to a change in their physical and chemical properties, a decrease in the yield of light petroleum products during oil refining, and a deterioration in the performance characteristics of engines. In this regard, it becomes difficult to start engines, their reliability, fuel consumption increases and the service life is reduced. Lost light hydrocarbons pollute the environment and increase the fire hazard of enterprises. The aim of the work is to identify effective, inexpensive and safe methods for reducing the volatility of oil products, including gasoline, when stored in tanks. Research methods. A retrospective analysis of studies on the problems of reducing losses of petroleum products during their storage, transportation and use is carried out. Technical and organizational methods for reducing the evaporation of fuels and the use of chemical additives as an inexpensive and effective method for solving the problem of the volatility of gasolines are considered. The conclusion about the efficiency of using chemical additives to fuels to reduce volatility has been substantiated. Results and their discussion. Conclusions are made about the possibility of using surfactants as additives to reduce the evaporation of gasolines during long-term storage in tanks. The analysis of the main components and methods for the synthesis of surfactant compositions capable of creating a surfactant film at the liquid-atmosphere interface, which protects the liquid from evaporation. Conclusion. Reducing the volatility of gasoline with the use of inexpensive and effective additives introduced into the fuel in small quantities, not only reduces the explosion and fire hazard during storage in large tanks, reduces losses, but also prevents the negative impact on the environment from the ingress of low molecular hydrocarbons into it. Key words: volatility of petroleum products, losses during storage of gasoline, methods of reducing volatility, additives.
On the assessment of the state of integrated security of industrial enterprises
Authors:   Moscow State University of Civil Engineering (National Research University), Gvozdev E. V. , Matvienko Yu. G. ,   Mechanical Engineering Research Institute of the Russian Academy of Sciences
Published: December 2021

Introduction. The article presents a methodically described, consistent algorithm for assessing the state of integrated safety of industrial enterprises that are classified as hazardous production facilities. A study was conducted in choosing a method that allows calculating the weighting coefficients of the estimated measures, the implementation of which is provided by services (structural divisions) performing labor functions to maintain the integrated security system of the enterprises under consideration at the required level. Goals and objectives. The main purpose of the article is to identify the causes of hazards in cases when the danger (accident or fire) occurs with the coverage of two or more departmental (industry) security subsystems that are part of the complex security of the enterprise. Reduction of hazards (accidents and fires) at industrial enterprises is carried out at the expense of resource investments directed to minimize (exclude) the conditions (prerequisites) for the occurrence of risky events that can be transformed into accidents or fires. However, due to the limitations of the resource allocated by the enterprise to ensure its comprehensive security, there is a need to identify those places (points) whose risk indicator is high (critical), requiring a response to them without delay. It is proposed to normalize each event included in the content of the checklist for checking the enterprise for both industrial and fire safety. Methods. The choice of the hierarchy analysis method is justified, the use of which, based on a pairwise comparison of factors and alternatives, allows us to determine a local priority indicator for each element under study. Results and their discussion. The algorithm of sequential actions presented in the article in the form of a detailed description allows you to set an indicator measured in the form of a quantitative value for each event held. Conclusions. An example is presented in a fragmentary form showing the order and sequence of obtaining local and global priorities, where the definition of local priorities indicates the weight of a characteristically described event that caused a hazard (accident and fire). Obtaining weighting factors in the form of global priorities is directly related to the services (structural divisions) performing labor functions to maintain the enterprise's integrated security system at the required level. Key words: complex security, hierarchy analysis, factor, evaluation indicator, expert, consistency ratio.
TO CHARACTERISTICS OF THE ETIOLOGICAL STRUCTURE AND ANTIBIOTIC SENSITIVITY PATHOGENSOF INFECTIOUS RESPIRATORY ORGANS IN NEWBORN AFTER ARTIFICIAL PULMONARY VENTILATION
Authors: LEVCHENKO B.I. , DMITRIEV D.V , BERTSUN K.T , BAGNYUK N.A. , NAZARCHUK O.A.
Published: December 2021

Objective. The study of the etiological structure, properties of pathogens of the Vinnytsia National Medical University named after E. Pirogova, respiratory process in newborns who have underwent artificial mechanical lung ventilation (MLV) and their resistance to antibacterial agents is especially relevant in modern conditions, expands the search for new approaches to pathogens, improves treatment and reduces mortality from this pathology.
The purpose of the study - to determine the etiological structure, sensitivity to antibiotics of the leading pathogens of the infectious process of the respiratory system in newborns who were on mechanical ventilation.
Materials and methods. In total, the species composition of the leading microorganisms that colonized the airways of 180 newborns treated in the Neonatal Intensive Care Unit (VAITN) of Vinnytsia Regional Children’s Clinical Hospital (VRCCH) was studied in 2020. A total of 285 isolates of microorganisms were isolated. 62 patients who underwent mechanical ventilation were involved in a prospective microbiological study, 86 clinical strains of microorganisms were isolated. The susceptibility of microorganisms to 30 antibacterial agents was determined according to the generally accepted method (order of the Ministry of Health of Ukraine №167; recommendations). Research results. The etiological significance of opportunistic pathogens (Enterobacter cloacae - 29%, Staphylococcus aureus - 24.4%, Pseudomonas aeruginosa - 18.6%, Candida albicans) was proved in patients who were on mechanical ventilation in VAITN VRCCH in 2020 for pneumonia. Clinical strains of S. aureus are sensitive to vancomycin, oxacillin and clindamycin.
Conclusions. Pathogens of the respiratory process in newborns who have been on mechanical ventilation, are resistant to a number of antibiotic drugs (cefepime, gentamicin amikacin, piperacillin).
РЕТРОСПЕКТИВНЫЙ АНАЛИЗ ПРИЧИН ЛЕТАЛЬНОСТИ У БОЛЬНЫХ С ТЯЖЕЛЫМ ТЕЧЕНИЕМ COVID-19
Authors: SEREDA S. , DUBROV S. , DENYSIUK M. , KOTLIAR O , CHERNIAIEV S. , ZAIKIN Y. , BARANOVSKA T , HAVRYLENKO O. , BORISOVA V. , PONYATOVSKA G.
Published: December 2021

In Ukraine, more than 3.5 million cases of COVID-19 have been registered during the pandemic, and the death toll is almost 90,000. Ukraine is a leader in Europe in the growth of new cases of COVID-19 and mortality from this disease. The search for effective treatment regimens and new approaches to the management of patients with coronavirus disease in order to reduce the severity of coronavirus disease, reduce mortality, the number of complications and improve the rehabilitation period is very important nowadays.
The aim of the work. To determine the main causes of mortality in patients with severe COVID-19 by analyzing the frequency and structure of complications in deceased patients.
Materials and methods. The study conducted a retrospective analysis of 122 medical charts of deceased patients with COVID-19 who were hospitalized in a communal non-profit enterprise “Kyiv city clinical hospital №17” for the period from September 2020 to November 2021.
Results and discussion. The overall mortality among patients with COVID-19 was 9.3%, in the intensive care unit (ICU) – 48.4%. The most common causes of death in patients with COVID-19 were: respiratory failure (RF) – 100% of cases, pulmonary embolism (PE) and acute heart failure (AHF) - about 60%. The average length of stay of patients in inpatient treatment was 11.67 ± 8.05 days, and in the intensive care unit – 7.94 ± 6.24 days. The mean age of patients hospitalized in the ICU was 63.5 ± 12.9 years and the mean age of patients who died was 71.2 ± 10.29 years.
Prognostically significant criteria for lethal consequences were the presence of comorbidity: cardiovascular diseases- 92.3%, endocrine system diseases – 28.4%, nervous system diseases – 23.07%, kidney diseases – 9.6%, cancer – 9,6%, autoimmune conditions – 7.69%, varicose veins – 5.7%, respiratory system diseases – 5.7%.
In patients with fatal outcome lymphopenia (84.6%) was observed in patients on admission to the ICU.
Vasopressor and inotropic support was performed in 50 % of patients with COVID-19. In 25 % of those who died during long-term treatment and long-term respiratory support, there was the development of multiple organ failure, which in most cases was the point of no return.
Conclusions. The most common causes of death were: respiratory failure, thrombosis, acute cardiovascular failure, sepsis and multiple organ failure. The main nature of the complications is common, but the cohort may be affected by different factors and the percentage of complications may differ in other hospitals.
Sistem Maparo Sebagai Solusi Peningkatan Perekonomian Masyarakat Ekonomi Syariah (MES) Di Era 4.0
Authors: Muallifatur Rosidah
Published: December 2021

Sistem maparo dalam bisnis yang ada pada peternakan kambing yang dapat meningkatkan ekonomi masyarakat, khusunya masyarakat Muslim yang ada di Desa Sadabumi Kecamatan Majenang Kabupaten Cilacap, menggunakan transaksi kerjasama yakni “mudharabah” istilah lokalnya adalah akad maparo. Akad/transaksi maparo sendiri diartikan sebagai sistem bisnis dalam bidang peternakan, dimana para produsen/peternak yang melakukan bisnis dilakukan bersama-sama dengan pihak pemilik modal. Investasinya yakni berupa kambing, selanjutnya produk kambing ini ketika sudah layak jual (dewasa) kemudian hasil dari produk yang dijual ini akan dibagi dengan pihak si pemilik modal (bagi hasil). Penelitian ini dilakukan di Desa Sadabumi, Majenang, Cilacap. Dimana peneliti terjun langsung kelapangan untuk meneliti, kemudian hasil penelitian berupa pendeskripsian yang ada di lapangan. Teknik pengumpulan data dalam riset ini yakni teknik observasi dan wawancara serta dokumentasi.  Hasil Penelitian membuktikan bahwa dalam bisnis melalui sistem maparo ini masuk bisnis dengan sistem mudharabah-muqayyadah. Dalam sistem maparo bisnis ini para pihak produsen dan pembeli tidak hanya dijadikan sebuah bisnis semata, melainkan tujuan maparo ini selain untuk bisnis adalah untuk menjalin hubungan silaturrahmi (persaudaraan) antar sesama muslim yang mana di era 4.0 Sistem bisnis maparo  juga menjadi salah satu sistem pengembangan usaha bagi pemilik modal. Akad mudharabah muqayyadah dalam sistem maparo merupakan manivestasi dari prinsip-prinsip dalam bisnis syariah, hal ini dikarenakan tujuan dari permodalan dalam bisnis ini yakni al-Ta’awun (tolong-menolong), keadilan dalam transaksi bagi hasil,  dan prinsip berbagi resiko dalam kerugian yang terjadi selama bisnis yang telah terjalin.
Biodegradation of Linear Alkylbenzene sulfonate-Anthracene Mixture by a Microbial Consortium isolated from Sediment
Authors: Pineda-Flores G. , Salgado-Brito R. , Mena-Cervantes V. , Hernández-Altamirano R. , García-Solares M.
Published: December 2021

Linear alkylbenzene sulfonate and anthracene are chemical compounds which form pollutant mixtures with high toxic potential, causing damage to ecosystems. The process known as biodegradation is an effective, low-cost process carried out by microbial populations that reduces the toxic effect of linear alkylbenzene sulfonate and anthracene. In the present study, biodegradation was determined at different concentrations of linear alkylbenzene sulfonate, anthracene and the mixture of both compounds. The resulting reduction in toxicity produced by the mixture, the compounds separately and their biodegradation intermediaries was assessed using a microbial model. The ISO 9439 system was used to assess the biodegradation effect of a microbial consortium isolated from polluted sediment on 5, 10 and 20 mg/l of linear alkylbenzene sulfonate and the same concentrations of anthracene. Toxicity was determined by measuring inhibition of Bacillus cereus dehydrogenase activity produced by 0.25 ml aliquots of the linear alkylbenzene sulfonate, anthracene and the mixture of both compounds before and after they had been subjected to the biodegradation test. After 11 days, the linear alkylbenzene sulfonate -anthracene mixture was biodegraded to a greater degree than the compounds individually (3057.36 μmol CO2), but at a concentration of 20 mg/l of both compounds, a marked inhibition of biodegradation was observed. A reduction in toxicity produced by the biodegradation of linear alkylbenzene sulfonate and its mixture with anthracene at 5 and 10 mg/l respectively was observed.
UHPLC analysis and in vitro biological activities of Areca triandra Roxb. ex Buch.-Ham.: a substitute of areca nut
Authors: Pathak Ashutosh , Das Rahul , Vijayan Deepu , Odyuo Nripemo , Baite David L. , Mao Ashiho A.
Published: December 2021

Areca triandra Roxb. ex Buch.-Ham. (Arecaceae) distributed in Assam, North Bengal plains, Meghalaya andaman and Nicobar Islands is used as a substitute for A. catechu L. (Areca Nut). A. catechu is widely used as masticator in South Asia. The present study was conducted to find out the phenolic acids present in A. triandra and potential of it in inhibiting the reactive oxygen species (ROS). Plant extracts obtained from leaf and nut were analyzed qualitatively, quantitatively and phenolic acids were identified and quantified using reverse phase chromatography method developed on through Hypersil Gold aQ C18 column in Thermo Scientific Dionex Ultimate 3000 UHPLC. Three antioxidant assays viz. DPPH, ABTS and reducing power assay were performed to assess the potential of A. triandra as an antioxidant. Antifungal susceptibility test was performed by Clinical Laboratory Standard Institute (CLSI) recommended broth microdilution assay and disk diffusion susceptibility assay using Tinidazole as standard. Total catechin content was 19.51% of total phenolic content in NME. The antioxidant property was observed in NME only for DPPH, ABTS and RPA assays. In antifungal activity, minimum effective concentration (MEC) was observed in NME at the concentration of 1.0mg/ml and above whereas in LME, no MEC was observed up to tested concentrations. A. triandra possesses high catechin content and has promising potential as an antioxidant agent.
Crosstalk between Inflammatory Bowel Disease Proteins and Neuroinflammatory Proteins for Understanding Involvement of Gut-Brain Axis in Parkinson’s Disease and Identified Drug Receptors: In-Silico Approach
Authors: Dogra Nitu , Jakhmola-Mani Ruchi , Katare Pande Deepshikha
Published: December 2021

Parkinson’s disease (PD) is a chronic, progressive and second most prevalent neurological disorder affecting the motor system. It has been found that people suffering with inflammatory bowel disease (IBD) are 22% more prone to PD. In the current study, we have framed a hypothesis and deciphered protein-protein interaction network between the IBD and PD and therefore, have proposed a role of gut-brain axis in PD. Text mining for retrieval of Differentially Expressed protein (DEPs; specific to Homo sapiens) associated with PD and IBD was done using Science Direct, Pub Med Central, Sci ELO and JSTOR. The protein interaction network was constructed in Cytoscape (version 3.7.1) by using above 58 DEPs. The generated master network was further analyzed using BiNGO plugin for retrieval of overrepresented biological processes in IBD-PD pathologies. Hub nodes were also generated in the network. In the present study the gutbrain hypothesis was designed which demonstrates the series of protein interactions that ought to link IBD to PD. Major proteins involved in this connection were LRRK2, APOE, SNCA, IL6, HIF-1α, ABCA, TLR4, CREB1, IL10, ADORA2A, DRD2, INOS, CCL2, SLC6A3 and CASP3. These proteins could be used as druggable targets to halt the progression of PD pathogenesis initiating via IBD. The common biological pathways linking both the pathologies were found to be HIF-signaling, Cytokines interactions, JAK-STAT pathway, Cholesterol metabolism, cAMP mediated signaling and apoptosis. This study also suggests the role ABC transporters and APOE in linking IBD and PD via disturbance of cerebral homeostasis.
Dane Mısır Üretimi Yapan İşletmelerin Damla Sulama Desteklemelerinden Faydalanma Durumunu Etkileyen Faktörler
Authors: CANDEMİR Serhan , AYDIN Başak , UYSAL Osman , AYTOP Yeşim
Published: December 2021

Bu çalışmada, Kahramanmaraş ilinde dane mısır üretimi yapan ve tarla içi damla sulama desteğinden yararlanan ve yararlanmayan işletmelerinin sosyo-ekonomik yapısı belirlenmiş ve damla sulama desteğinden faydalanma durumunu etkileyen faktörler tespit edilmiştir. Çalışmanın materyalini, Kahramanmaraş ilinde 2012-2017 yılları arasında Tarım ve Orman Bakanlığı tarafından verilen damla sulama desteğinden yararlanan ve yararlanmayan üreticilerle yapılan anket çalışmaları oluşturmaktadır. Basit tesadüfi örnekleme yöntemine göre 45 damla sulama desteği alan dane mısır üreticisiyle anket çalışması yapılmış olup, aynı sayıda damla sulama desteğinden yararlanmayan ve salma sulama yapan dane mısır üreticisi ile de anket çalışması yapılmıştır. Üreticilerin damla sulama desteği alma eğilimleri ve bu eğilimlerinde etkili olan faktörler lojistik regresyon analizi kullanılarak belirlenmiştir. Üreticilerin yaşlarının, eğitim sürelerinin, aile birey sayılarının, toplam işledikleri arazi büyüklüğünün ve toplam tarımsal gelirlerinin damla sulama desteği alma durumunu pozitif, tarımsal deneyimlerinin, ailelerinde tarımda çalışan kişi sayısının ve dane mısır üretim alanının ise negatif yönde etkilediği

belirlenmiştir. Elde edilen bulgular doğrultusunda tarımsal üretimde damla sulama sisteminin kullanımının yaygınlaştırılmasında karar vericiler tarafından çeşitli stratejiler geliştirilebilir ve söz konusu desteklemenin etkilerine göre politikalar geliştirilerek gelecek nesillere aktarılacak kısıtlı kaynakların etkin kullanımı sağlanabilir.
TEST RESULTS FOR TOXICITY AND REDUCING TOXIC EXHAUST EMISSIONS OF THE MARINE DIESEL ENGINE
Authors:   Naval Technical Institute, Vietnam, Pham Van Ha , Nguyen Ha Hiep ,   Le Quy Don Technical University, Vietnam
Published: December 2021

The tests were carried out on the marine diesel engine operating by the load characteristic in seven modes, including five modes according to the test cycle D2 regulated by ISO 8178. Based on the experimental results obtained, the specific weighted NOx emissions and their average values were calculated and compared with IMO regulations. In addition, the study carried out a comparative experimental investigation on diesel fuel and dimethyl ether, and different injector opening pressures in the marine diesel engine to reduce its toxic exhaust emissions.
ON ONE PROVISION OF THE TEXTBOOK «THE PAGES OF JEWISH HISTORY OF UKRAINE»
Authors:   Hetman Petro Sahaidachnyi National Ground Forces Academy, Gulyma Oleksandr , Opelbaum Julius ,   Associate Professor
Published: December 2021

The authors analyze the statement that during the short period of the existence of the Western Ukrainian National Republic (WUNR) the majority of Jews in Galicia had not decided whose interests they should support, those of the Ukrainians or the Poles, and did not have time to realize themselves as citizens of the new Ukrainian state. It is shown that this statement is controversial and contradicts the multiperspectival approach to the study and teaching of history.
THE POST-TRUTH CONCEPT IN THE CONTEMPORARY SCIENTIFIC DISCOURSE
Authors:   Taras Shevchenko National University of Kyiv, Trachuk Tetiana
Published: December 2021

The article analyzes the definition of "post-truth" in Ukrainian and foreign scientific and popular science sources. Semantically, this concept turns out to be rather vague and is often analyzed by scholars as a sociocultural and political phenomenon of the postmodern era, or considered within the propagandistic and manipulative segment of modern media.
SOCIAL ECONOMY AND SOCIAL POLICY: COMMON FEATURES AND DIFFERENCES (THEORETICAL ASPECTS)
Authors:   Lviv University of Business and Law, Skrynkovskyy Ruslan , Tyrkalo Yuriy ,   Lviv Polytechnic National University
Published: December 2021

The article reveals the essence, features of the formation and implementation of the social economy and social policy based on the models, functions and principles of their implementation. It has been determined that the social economy is a direction of the general economy of the state, which is based right to work, the right to social security. It was found that social policy is one of the main components of the stability of the development of society. It has been established that the basic principles of social economy are: the principle of democratic control over society; the principle of taking into account the interests of society in the context of achieving the general interest of the social economy; the principle of solidarity; the principle of responsibility; the principle of autonomy of management; the principle of independence from the influence of state bodies; the principle of the rule of law; the principle of humanism; the principle of freedom; the principle of employment of the population; the principle of social protection and compliance with social guarantees. It has been established that the main principles of social policy are: the principle of social justice; the principle of social differentiation; the principle of targeted support for vulnerable groups of the population; the principle of providing protection to all categories of the population; the principle of social partnership; the principle of social balance; the principle of ensuring stability in society; the principle of ensuring the implementation of social programs; the principle of showing compassion and understanding the needs of socially vulnerable members of society; the principle of maximizing the living wage; the principle of ensuring support for peace and harmony among citizens and society as a whole. It is noted that the models of the social economy are the transitive model, the mediterranean model, the liberal model, the continental and scandinavian models. It has been established that the implementation of social policy passes through the «Bismarckian» model, the Beveridge model, the social democratic model, the corporatist model, the catholic model and the rudimentary model. It is proposed to investigate the features of the implementation of the social economy and social policy in Ukraine in the future.
FEATURES AND PROSPECTS OF DEVELOPMENT OF HYDROGEN ENERGY SYSTEMS IN THE REGIONS OF UKRAINE
Authors:   Lesya Ukrainka Volyn National University, Pavlova Olena , Pavlov Kostiantyn ,   Lesya Ukrainka Volyn National University, Novosad Oksana ,   Lesya Ukrainka Volyn National University, Shabala Oleksandr ,   Lesya Ukrainka Volyn National University
Published: December 2021

The article deals with modern environmental and technological challenges of the energy market development process. The necessity and key vectors of functioning of the renewed energy system, where an important role is assigned to increasing the energy efficiency of measures for the prevention and adaptation of climatic changes to the global energy trend, have been clarified. As a result, there is an active introduction of innovative measures in the energy sector of Ukraine and regions. This can be traced in the segments of production, processing, transportation, storage and consumption of energy resources. The main document has been processed, which specifies and implements the main stages of the transformation of the energy sector: "Energy strategy of Ukraine for the period up to 2035: safety, energy efficiency, competitiveness." It is noted that the implementation of the strategic changes specified in the document is important and most acceptable, subject to the influence of sectoral, regional, socio- economic factors and the resolution of the escalation of the Ukrainian-Russian conflict. The future development of Ukraine is modeled in the conditions of decarbonization of energy, where the main place will belong to the hydrogen direction. The stages and features of the formation of hydrogen energy, the natural properties of hydrogen are considered, the world practice is considered. The priority and economically justified methods of using hydrogen to produce ammonia and as an alternative resource for oil and gas are noted and proposed. However, several obstacles are highlighted that institutionally prevent Ukraine and the regions from fully using hydrogen technologies.
CONCEPTUAL PRINCIPLES OF ADMINISTRATIVE PROCEDURES FOR THE FORMATION OF THE STATE DEFENSE ORDER
Authors:   Yaroslav Mudryi National Law University, Povydysh Vladyslav
Published: December 2021

The author proposed his own definition of the legal regime of relations in the field of formation of the state defense order. At the same time, based on modern doctrinal views on the assessment of the purpose of the basic structures of defense procurement, which are determined by the specifics of these relations, attention is focused on the need for administrative and legal influence on them, but within strictly limited limits. Analyzing a number of legislative acts, doctrinal achievements of leading scientists, making their own author's interpretation of some phenomena, the author found that the current legislation of Ukraine is insufficiently filled with sectoral rules of administrative procedure for forming the state defense order, as evidenced by the lack of procedures defense procurement. In addition, the legislation does not define certain administrative barriers to the procedures, which puts the state customers in a priority position before the general executor, which is a negative factor given the "service" orientation of Ukraine's development. The author found insufficient scientific development in terms of understanding, interpretation and explanation of the concept of "administrative procedure". A complete and extensive understanding of this area was provided, and the author's understanding of the administrative procedure was provided. An explanation of the administrative procedure for forming a defense order is also provided. In addition, the conceptual principles of the administrative procedure of defense order formation were studied, the zones of their interaction and interdependence were established, each of the basic principles was explained and their implementation incomplete to date in Ukraine was proved. In addition, the author found that the legislator rarely manages to ensure the optimal combination of multidisciplinary norms. As a result, there are such negative trends as ineffective regulation, the formation of destructive legal mechanisms that hinder the normal functioning of legal relations. These trends are fully inherent in the sphere of state defense procurement.
LAWYER AND CLIENT RELATIONS: UKRAINIAN AND FOREIGN PRACTICES
Authors:   Yaroslav Mudryi National Law University, Marochkin Oleksii , Leshko Oksana ,   Yaroslav Mudryi National Law University
Published: December 2021

The scientific article is devoted to the analysis of issues related to the peculiarities of the relationship between a lawyer and a client in Ukraine and foreign countries. In the article, the author analyzes the provisions of the Law of Ukraine "On the Bar and Advocate Activity" and the Rules of Lawyer Ethics concerning such aspects of the relationship between an attorney and a client as confidentiality, preservation of attorney secrecy, payment of an attorney's fee and determination of the legal nature of an attorney's "success fee". The works of domestic and foreign scientists, the subject of which the author identified the questions, have been investigated. The author defines trust as the basis of the relationship between the client and the lawyer, defines its value and normative dimension; the issues of possible abuse of confidence on the part of a lawyer were considered. It has been established that the principle of confidentiality is not absolute and when it is applied, there are exceptions provided for by the Rules of Lawyer Ethics. The author draws attention to the fact that neither the legislator, nor the all-Ukrainian bodies of advocate self-government determine the criteria for the reasonableness of the amount of the fee. The available decisions of the councils of lawyers of individual regions on the approximate amount of the fee are of a recommendatory nature. The obligation of a lawyer was established to provide in the agreement on the provision of legal assistance provisionsregarding the procedure for payment conditions, return of fees; the possibility of agreeing on the payment of the “success fee” with the client was determined. The author has analyzed the practice of consideration of disciplinary complaints by the Higher Qualification and Disciplinary Commission of the Bar on certain issues of preserving attorney secrets and attorney fees. The experience of the United States of America, Great Britain and France in the aspect of normative regulation and law enforcement of the issues identified in scientific work is investigated. The author identified both the general characteristics of the relationship between a lawyer and a client in Ukraine and foreign countries, as well as excellent ones. The general characteristics of the relationship between a lawyer and a client can be traced in matters of the concept of lawyer secrecy and the guarantee of its nondisclosure. Distinctive characteristics - in matters of the type of responsibility for the disclosure of attorney secrets and the availability of mandatory criteria for the reasonableness of the amount of the attorney's fee.
COVER, DAFTAR ISI, ISI
Authors: Isi Cover Daftar Isi
Published: December 2021

COVER, DAFTAR ISI, ISI
PERAN KAPABILITAS INTERAKSI DAN KREASI NILAI BERSAMA UNTUK MENINGKATKAN KINERJA PEMASARAN
Authors: Sudarti Ken , Wardhiani Okky
Published: December 2021

ABSTRACTThis study focuses on the role of Individual and Relational Interaction Capability in increasing Emotional and Social Value Co-Creation on Market Performance in beauty salon services. Value Co-Creation is one of the service organization's strategies in utilizing external resources from customers. This strategy is crucial because the performance of service organizations is mostly determined by the ability of the frontline staff who interact with customers during service meetings. This research belongs to explanatory research with a population of beauty salon customers in Central Java. The sample consisted of 203 customers, and it was determined using the purposive sampling technique. The author collects customer data through the distribution of offline and online questionnaires analyzed using SPSS 23.0-based regression. This study has proven that Emotional and Social Value Co-Creation can mediate between Individual and Relational Capability with Market Performance. Emotional and social values that are created together will be beneficial for the parties involved. For customers, interactions during the value co-creation process will increase their satisfaction because it can fulfill their needs and desires. This study has also shown the role of individual and relational capability in increasing customer willingness to engage in mutual value creation interactions.JEL  Codes: D20, L10, M20.Keywords : individual interaction capability, relational interaction capability, emotional value co-creation, social value co-creation, market performance. ABSTRAKStudi ini fokus pada peran Individual dan Relational Interaction Capability dalam meningkatkan Emotional dan Social Value Co-Creation menuju Market Performance pada jasa salon kecantikan. Value Co-Creation merupakan salah satu strategi organisasi jasa dalam memanfaatkan sumberdaya eksternal yang berasal dari pelanggan. Strategi ini sangat penting karena performa organisasi jasa sangat ditentukan oleh kemampuan frontline staff dalam berinteraksi dengan pelanggan pada saat pertemuan jasa. Jenis penelitian bersifat explanatory research dengan populasi pelanggan salon kecantikan di Jawa Tengah. Ukuran sampel yang digunakan sebanyak 203 pelanggan. Teknik pengambilan sampel menggunakan pPurposive sSampling. Peneliti mengumpulkan data pelanggan melalui penyebaran kuisioner secara offline dan online. Alat analisis data menggunakan regresi berbasis SPSS 23.0. Studi ini telah berhasil membuktikan bahwa Emotsional dan Social Value Co-Creation mampu memediasi antara Individuasl dan Relational Capability dengan Market Performance Nilai emosional dan soscial yang dikreasikan bersama akan bermanfaat bagi pihak-pihak yang terlibat. Bagi pelanggan, interaksi selama proses value co-creation akan meningkatan kepuasannya karena kebutuhan dan keinginannya dapat terpenuhi. Studi ini juga telah membuktikan peran individual dan relational capability dalam meningkatkan keinginan pelanggan terlibat dalam interaksi penciptaan nilai bersama.