bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between living in municipalities with high crowding conditions and poverty and mortality from COVID-19 in Mexico
Authors: Ríos Viridiana , Denova-Gutiérrez Edgar , Barquera Simón
Published: February 2022

Background

The World Health Organization stated a pandemic by severe acute respiratory syndrome coronavirus SARS-Cov2 (COVID-19) on March, 2020 with devastating implications for populations, healthcare systems, and economies globally.

Objective

The present study explores the association between patients living in municipalities with crowding conditions and poverty and mortality from COVID-19 in Mexico; specifically evaluating the socioeconomic characteristics of the municipality in which the patients reside and some individual characteristics.

Methods

In the present study, we examined public information collected from the National Epidemiological Surveillance System informing all persons tested for SARS-CoV-2 and published by the Ministry of Health. The present analysis was restricted to those with the date of registration to October 12, 2021. The association between the main exposures (overcrowded conditions and poverty) and the outcomes of interest (death by COVID-19) was explored using Cox proportional hazard regression models, including frailty penalties to accommodate multilevel data and random effects for the municipality of case occurrence.

Results

A total of 9619917 subjects were included in the Epidemiological Surveillance System for viral respiratory disease platform. Of those for which results were available, 6141403 were negative for COVID-19 and 3478514 were positive for COVID-19; with a total of 273216 deaths in those who tested positive. Among those positive to COVID-19 mean age was 46.9. Patients living in municipalities with high rates of crowding conditions increased the risk of dying from COVID-19 by 8% (95% CI: 1.03, 1.14). Individuals living in municipalities with indigenous background was associated with an increased risk of dying from COVID-19 (HR = 1.10; 95% CI: 1.04, 1.17). Individuals living in municipalities with illiteracy (HR = 1.09; 95% CI: 1.03, 1.11), poverty (HR = 1.17; 95% CI: 1.14, 1.19), food insecurity (HR = 1.094; 95% CI 1.02, 1.06), limited access to social security (HR = 1.10; 95% CI: 1.08, 1.13) and health services (HR = 1.06; 95% CI: 1.04, 1.08) had a higher risk of mortality from COVID-19.

Conclusion

Our data suggest that patients living in municipalities with higher rates of crowding conditions and higher rates of poverty had elevated risk of mortality from COVID-19. In Mexico, the COVID-19 pandemic is a systemic crisis linked to human development since we have seen that it affects less developed and more vulnerable municipalities. Policies to reduce vulnerabilities and develop strategies to deal with health crises like the current one needs to be considered.
Serum uric acid level and all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and dose-response meta-analysis of cohort studies
Authors: Kang Ting , Hu Youchun , Huang Xuemin , Amoah Adwoa N. , Lyu Quanjun
Published: February 2022

Background

The association between serum uric acid (SUA) and all-cause and cardiovascular disease (CVD) mortality in peritoneal dialysis (PD) patients is controversial. Therefore, we aimed to determine the relationship between SUA and all-cause and CVD mortality in PD patients.

Method

Web of Science, EMBASE, PubMed and the Cochrane Library databases were searched from their inception to 7 April 2021. Effect estimates were presented as hazard ratios (HRs) with 95% confidence intervals (95% CIs) and pooled using random effects model.

Result

Thirteen cohort studies with 22418 patients were included in this systematic review, of which 9 were included in the meta-analysis. Before switching the reference group, pooled result for the highest SUA category was significantly greater than the median for all-cause mortality (HR = 2.41, 95% CI: 1.37–4.26). After switching the reference group, the highest SUA category did not demonstrate an increased all-cause (HR = 1.40, 95% CI: 0.95–2.05) or CVD (HR = 1.30, 95% CI: 0.72–2.34) mortality compared with the lowest SUA category. Dose-response analysis suggested a nonlinear association between SUA and all-cause mortality risk (Pnonlinearity= 0.002).

Conclusion

This meta-analysis didn’t find the relationship between SUA levels and all-cause and CVD mortality risk in PD patients. More rigorously designed studies are warranted in the future.
Imaging visuospatial memory in temporal lobe epilepsy—Results of an fMRI study
Authors: Schmidbauer Victor , Nenning Karl-Heinz , Schwarz Michelle , Foesleitner Olivia , Mayr-Geisl Gudrun , Yildirim Mehmet Salih , Pirker Susanne , Moser Doris , Denk Daniela , Prayer Daniela , Trimmel Karin , Langs Georg , Baumgartner Christoph , Pataraia Ekaterina , Kasprian Gregor , Bonelli Silvia
Published: February 2022

Purpose

Impairment of cognitive functions is commonly observed in temporal lobe epilepsy (TLE). The aim of this study was to assess visuospatial memory functions and memory-related networks using an adapted version of Roland’s Hometown Walking (RHWT) functional MRI (fMRI) task in patients with TLE.

Methods

We used fMRI to study activation patterns based on a visuospatial memory paradigm in 32 TLE patients (9 right; 23 left) and also within subgroups of lesional and non-lesional TLE. To test for performance, a correlational analysis of fMRI activation patterns and out-of-scanner neuropsychological visuospatial memory testing was performed. Additionally, we assessed memory-related networks using functional connectivity (FC).

Results

Greater contralateral than ipsilateral mesiotemporal (parahippocampal gyrus/hippocampus) activation was observed in left (n = 23)/right (n = 9) TLE. In lesional left TLE (n = 17), significant activations were seen in right more than left mesiotemporal areas (parahippocampal gyrus), while non-lesional left TLE patients (n = 6) showed significant bilateral (left>right) activations in mesiotemporal structures (parahippocampal gyrus). In left TLE, visuospatial cognitive testing correlated with fMRI activations in left (parahippocampal gyrus) and right mesiotemporal structures (hippocampus), characterized by greater fMRI activation being associated with better memory scores. In right TLE, higher scores in visuospatial memory testing were associated with greater fMRI activations in left and right insular regions. FC patterns of memory-related networks differ in right and left TLE.

Conclusion

While TLE in general leads to asymmetrical mesiotemporal activation, lesion-induced and non-lesional TLE patients reveal different memory fMRI activation patterns. In right TLE, insular regions try to compensate for impaired right mesiotemporal structures during the performance of visuospatial tasks. Underlying functional visuospatial memory networks differ in right and left TLE.
Medicina, médicos y hospitales en el cine de Almodóvar
Authors: Alonso Franch Eduardo
Published: February 2022

El presente artículo supone una contribución al tema del título. En él se hace referencia a la obra de Almodóvar en las últimas cuatro décadas como ejemplo y paradigma del cine español, siendo tal vez su director con más éxito público y de crítica, amén de algunos Oscars para él y sus colaboradores. La medicina juega en su obra un importante papel: médicos y enfermeras, pacientes y transexuales, drogas y drogodependientes, hospitales y ambulatorios aparecen en sus películas. Madrid y Barcelona, así como La Coruña, son las provincias en las que se desarrollan sus narraciones cinematográficas. Las protagonistas femeninas abundan en su filmografía: Marisa Paredes, Penélope Cruz y otras aparecen con frecuencia y de forma repetida. En general, la época suele ser la contemporánea a la de su realización, con alguna excepción referida a 1970. Antonio Banderas es otro de sus actores fetiche, apareciendo en varias ocasiones como médico.
EXTERNALIDADES NA INSTALAÇÃO DE ESTABELECIMENTOS PRISIONAIS NOS MUNICÍPIOS BRASILEIROS: PROPOSTAS LEGISLATIVAS PARA O ATENDIMENTO DO PRINCÍPIO DA EFICIÊNCIA ECONÔMICO-SOCIAL
Authors: Granzotto Eduardo , Bauer  Pertille Marcelo , Silveira Pertille Thais
Published: February 2022

O Brasil enfrenta um estado de coisas inconstitucional no que se refere às condições do sistema prisional brasileiro. Para contornar o problema, uma das medidas necessárias é construção de novas unidades penais. Porém, grande parte dos Municípios brasileiros se coloca como um entrave, diante das externalidades negativas acarretadas. Este estudo buscará responder se uma análise econômica do Direito, realizada a partir do princípio da eficiência econômico-social, pode contribuir para dissolução do impasse ocasionado entre a necessidade de aumento de vagas nos presídios e a resistência dos Municípios em recebê-los. Trata-se de pesquisa qualitativa exploratória, de procedimento monográfico, de abordagem dedutiva e técnica de pesquisa a bibliográfica. Conclui por possíveis alterações legislativas que podem ser adotadas para que as externalidades negativas sejam minimizadas e/ou contornadas no sentido da concretização do princípio da eficiência econômico-social.PALAVRAS-CHAVE: Crise prisional, Novos estabelecimentos penais e a recusa de municípios, princípio da Eficiência Econômico-Social, Análise econômica do Direito, Propostas legislativas.
ALTERIDADE, DIFFERÁNCE E MINISTÉRIO PÚBLICO EM TEMPOS DE CORONAVÍRUS
Authors: Souza Cruz Álvaro Ricardo de , Nogueira Bernardo G. B. , Silva Diogo Bacha e
Published: February 2022

O artigo apresenta a atuação do Ministério Público em meio à pandemia do coronavírus e busca uma reinterpretação dos princípios constitucionais da unidade institucional e independência funcional que estruturam a atuação ministerial na Constituição de 1988. A partir da fenomenologia derridiana, a interpretação fechada dos princípios tanto pode ser considerada como veneno ou remédio para o Estado Democrático de Direito. Então, a saída é para o infinito, o Outro, o Rosto. PALAVRAS-CHAVE: Ministério Público, Unidade institucional, Independência funcional, Estado Democrático de Direito.
O DIÁLOGO ENTRE PODERES E O REEQUILÍBRIO INSTITUCIONAL: A (IN)EFICIÊNCIA DO DIÁLOGO NO COMBATE AO EMPODERAMENTO JUDICIAL
Authors: Britto Melina Carla de Souza , Erzinger Fernanda Huss , Barbosa Claudia Maria
Published: February 2022

Investiga-se a interação dialógica entre Legislativo e Judiciário e se tal diálogo pode ser um instrumento para combater o empoderamento judicial ou se acaba servindo de disfarce para o exercício do poder decisório sobre questões políticas, sociais e econômicas pelo Judiciário. Indaga-se se o diálogo institucional conseguiria romper a supremacia estabelecida pelo Judiciário. Averígua-se se o diálogo, por si só, é capaz de restabelecer o equilíbrio necessário entre o Legislativo e o Judiciário. O que se constata, por intermédio do método dedutivo de análise e de um estudo de revisão bibliográfica é que podem existir argumentos a favor e contrários ao diálogo institucional e que ele pode servir para combater a supremacia judicial e o sufocamento dos demais poderes. Percebe-se que o que lhe falta é a eficiência no diálogo aberto e entre iguais, bem como a participação popular, prezando pelo prevalecimento da democracia e do constitucionalismo.  PALAVRAS-CHAVE: Separação de poderes, Poder Judiciário, reequilíbrio institucional, diálogo institucional.
A REPÚBLICA, A PAIDEIA ÔNTICA, A JUSTIÇA E A IDEIA DO BEM A PARTIR DO JUSNATURALISMO ONTOLÓGICO DE PLATÃO
Authors: Santos Rafael Padilha dos
Published: February 2022

Na obra A República de Platão (428/427-348/347 a.C.) o conceito de justiça é premissa fundamental para se formar um líder político, para que um ser humano se oriente pela virtude, para que a sociedade seja organizada em harmonia, para se alcançar a finalidade de felicidade pública na polis, para uma educação humanista. A compreensão da ideia da justiça envolve também entender a célebre expressão “conhece-te a ti mesmo” em sua base ontológica. Assim, o objetivo deste artigo é estudar a justiça no pensamento de Platão, partindo do fundamento jusnaturalista ontológico que caracteriza a sua República, relacionando a justiça com a ideia de bem e a paideia ôntica. Este artigo se insere na linha de pesquisa de constitucionalismo e produção do direito, partindo da filosofia política de Platão. Vale destacar que um governante, para Platão, não encontra o apogeu dos seus estudos na ideia de justiça, há um estudo superior que ele deve ainda realizar, que é o da ideia do Bem. A ideia do Bem é a mais elevada das ciências, está ligada à metafísica/ontologia, de modo que a justiça, sabedoria, coragem, temperança somente se tornam úteis e valiosas em razão da ideia do Bem. A fundação da República, portanto, depende do saber ontológico por parte das lideranças, que podem assim organizar uma polis calcada na ideia do Bem, para a partir daí se capacitarem à realização do que é a justiça, tanto a justiça na polis quanto a justiça no indivíduo. O método para a construção das ideias deste produto acadêmico é o indutivo, sendo os dados recolhidos a partir da pesquisa bibliográfica, sendo o principal referente teórico a obra A República de Platão.
Hepatitis B Core-Related Antigen Stratifies the Risk of Liver Cancer in HBeAg-Negative Patients With Indeterminate Phase
Authors: Tseng Tai-Chung , Hosaka Tetsuya , Liu Chun-Jen , Suzuki Fumitaka , Hong Chun-Ming , Kumada Hiromitsu , Yang Wan-Ting , Hsu Chen-Yang , Su Tung-Hung , Yang Hung-Chih , Liu Chen-Hua , Chen Pei-Jer , Chen Hsiu-Hsi , Kao Jia-Horng
Published: February 2022

INTRODUCTION:

Many patients with chronic hepatitis B (CHB) are classified as indeterminate patients because they fall outside the defined CHB phases. We aimed to explore hepatocellular carcinoma (HCC) risk in hepatitis B e antigen (HBeAg)-negative patients with indeterminate phase and investigated whether the risk could be stratified by serum levels of hepatitis B core-related antigen (HBcrAg).

METHODS:

Two retrospective cohorts enrolling HBeAg-negative, treatment-naïve CHB patients without cirrhosis were constructed (N = 2,150 in Taiwanese discovery cohort and N = 1,312 in Japanese validation cohort with a mean follow-up period of 15.88 and 12.07 years, respectively). The primary end point was HCC development.

RESULTS:

According to the American Association for the Study of Liver Disease guidelines, 990 (46%) HBeAg-negative patients had indeterminate CHB phase at baseline in the Taiwanese cohort. Compared with the patients with inactive CHB and those with immune-active CHB, the indeterminate patients exhibited intermediate but diverse risk of HCC. When HCC risk was stratified by a HBcrAg level of 10,000 U/mL, 10-year HCC cumulative incidence was 0.51% and 5.33% for low HBcrAg and high HBcrAg groups, respectively, with a hazard ratio of 4.47 (95% confidence interval: 2.62–7.63). This cutoff was validated to stratify HCC risk not only in different subgroup analyses but also in an independent Japanese cohort. Finally, the overall HBeAg-negative CHB patients could be simply reclassified into high-risk and low-risk groups by combining ALT, hepatitis B virus DNA, and HBcrAg levels in both cohorts.

DISCUSSION:

Serum HBcrAg level of 10,000 U/mL stratifies HCC risk in HBeAg-negative patients with indeterminate phase, which is useful for optimizing their clinical management.
Frequency of intestinal protozoan infections diagnosed in patients from a clinical analysis laboratory
Authors: Tarciane Lilia dos Santos  , Antônio de Pádua Medeiros de Carvalho Neto  , José Rodrigo da Silva Ferreira  , Paulo Victor Muniz Azevedo  , Karwhory Wallas Lins da Silva  , Cícera Maria Alencar dos Nascimento  , Claudia Maria Lins Calheiros  , Flaviana Santos Wanderley  , Marília Gabriela dos Santos Cavalcanti  , Mabel Alencar do Nascimento Rocha  , Rocha Thiago José Matos-
Published: February 2022

This study aimed to determine the frequency of infection by intestinal protozoa diagnosed in patients from a clinical analysis laboratory in Maceió, Alagoas, Brazil. This was a retrospective descriptive study, using a database of stool examination results from July to December 2015. The study population consisted of males and females of all ages, from the greater area of Alagoas. Data on epidemiological variables such as age and gender were obtained using a collection instrument. Protozoan species were identified from stool examinations. Results on the prevalence of intestinal parasites are described as simple and relative frequencies. We examined a total of 1277 stool samples, of which 12.69% were positive for one or more protozoa. 43.83% were from men and 56.17% were from women. Endolimax nana was the most prevalent (59.22%) protozoan species followed by Entamoeba coli (23.45%). Although non-pathogenic, they indicate fecal contamination of drinking water. The highest number (23.46%) of infected individuals was observed among children in the 0 to 11 years age group. A high prevalence (93.83%) of monoparasitism was noted. We concluded that there was a high frequency of infection and a high prevalence of E. nana. Infections were more common in women than in men. Our results emphasize the need for preventive measures to control intestinal parasitic infections.
Accelerated aging test in the determination of safflower seeds vigor
Authors: Coelho Mirelle Vaz , Silva Ingrid Maressa Hungria de Lima e , Silva Amalia Andreza Sousa , Paz Rogério Borges de Oliveira , Rocha Diego Ismael , Machado Carla Gomes , Silva Givanildo Zildo da
Published: February 2022

In assessing the quality of seed lots, the vigor tests are complementary to the germination test and they identify differences in the degree of deterioration of the lots. For safflower, there is little information regarding these tests. In this way, the intention of this study was to adapt the accelerated aging test methodology to assess the physiological potential of safflower seeds (Carthamus tinctorius). For this purpose, 12 seed lots were evaluated for thousand-seed weight, germination, first germination count, seedling emergence test (emergence percentage, emergence speed index, relative emergence frequency and the initial, final and mean times) and accelerated aging. For the accelerated aging test, the traditional and saline methods were used. For this, the samples were conditioned in periods of 0, 8, 16, 24, 32 and 48 hours at 42 °C. Afterwards, they were submitted to the germination test, with evaluation of normal seedlings on the 3rd day. The 12 lots were evaluated within each period, in independent experiments. The data were submitted to analysis of variance and the means were compared using the Scott-Knott clustering method at 5% probability. In the traditional accelerated aging test the periods of 16, 24, 32 and 48 hours were more efficient in differentiating the lots in vigor levels, as they stratified the lots in three classes and the time of 8 hour classified the lots in two levels of vigor. In the accelerated saline aging method the time 32 hours were more efficient since it ranked seed lots at three levels of vigor and the periods of 8, 16 and 24 hour stratified the lots in two levels. In results obtained by the principal component analysis it was verified. The variables traditional accelerated aging for 24 and 32 hours correlated with emergence in the field. Therefore, the traditional accelerated aging test at 42 °C for 24 hours are promising for evaluating the physiological quality of safflower seeds.
Synthesis, antimicrobial evaluation and in silico studies of the (E)-3-(aryl)-5-styryl-1,2,4-oxadiazoles
Authors: Lima Josefa Aqueline da Cunha , Costa Erick Caique Santos , Bezerra Giselle Barbosa , Silva Jadson de Farias , Alves Caiana Rodrigo Ribeiro , De Freitas Filho Joao Rufino , Freitas Juliano Carlo Rufino
Published: February 2022

In recent years, investigations in the field of oxadiazoles have been intensified due to their numerous therapeutic uses. Oxadiazoles are a class of compounds that exhibit several biological applications, citing antimicrobial, anti-inflammatory, anti-diabetic, anthelmintic, anti-tumor, among others. Encouraged by the biological potential of oxadiazoles, were carried out synthesis, antimicrobial evaluation and in silica studies of five (E)-3-(aryl)-5-styryl-1,2,4-oxadiazoles. In this way, (Z)-aryl-N'-hydroxybenzimidamides and ethyl (E)-cinnamate were synthesized, which were subjected to an O-acylamidoxime reaction after by dehydration using microwave irradiation to form the oxadiazole nucleus. The compounds were characterized by spectroscopic techniques, while in vitro antimicrobial activity was evaluated against S. aureus, E. faecalis, E. coli, P. aeruginosa, and against the fungus C. utilis using the microplate microdilution method. Thus, (Z)-aryl-N'-hydroxybenzimidamides, ethyl (E)-cinnamate, and (E)-3-(aryl)-5-styryl-1,2,4-oxadiazoles were synthesized with yields ranging from moderate to good. The (E)-3-(aryl)-5-styryl-1,2,4-oxadiazoles exhibited a reduced spectrum of action, which were active against the bacterium P. aeruginosa and for the fungus C. utilis.
Effect of type of mature embryo explants and acetosyringone on agrobacterium-mediated transformation of moroccan durum wheat
Authors: Ahansal Khadija , Abdelwahd Rabha , Udupa Sripada , Aadel Hanane , Gaboun Fatima , Ibriz Mohammed , Iraqi Driss
Published: February 2022

Drought is one of the major constraints in durum wheat production in the Mediterranean Basin. In order to overcome this problem, the genetic transformation of durum wheat is one of the choices for improvement. However, the recalcitrance to Agrobacterium-mediated transformation in durum wheat (Triticum turgidum L.) is one of the factors limiting a successful genetic transformation. The aim of this study was to investigate the effect of explant type and acetosyringone concentration for the efficient Agrobacterium-mediated genetic transformation of three Moroccan durum wheat varieties (Amria, Chaoui, and Marouane). The mature embryos (intact, halved and pieces) were inoculated with Agrobacterium tumefaciens strain EHA101 harboring the binary vector pTF101.1 containing drought tolerance gene HVA1 from barley, and a selectable marker phosphinothricin (PPT) resistance (bar) gene. The explants were inoculated with A. tumefaciens (cell density OD650 at 0.7) at four different concentrations of acetosyringone (0, 100, 200, and 400 µM). The results showed that embryogenic calli from mature embryos showed higher regeneration and transformation than mature embryo halves and pieces. The integration of the transgene was confirmed by PCR amplification using primers specific to the bar gene, 2x35S promoter, and HVA1 gene. The transformation efficiency ranging from 0.33% to 2.33% was obtained in Amira variety using embryogenic calli and acetosyringone concentrations of 200 and 400 µM. The integration, as well as inheritance of the transgene, was confirmed by PCR amplification in T0 and T1 generations. This is the first report describing a genetic transformation of Moroccan durum wheat varieties via Agrobacterium tumefaciens.
Seed size and presence of thorns in Caryocar brasiliense on seedling emergence
Authors: Carmona Ricardo , Nunes Ferreira Daniel Franklin , Da Costa Thiago Estácio , Carvalho Júnior Luís Carlos , Alves de Oliveira Júnior Antônio
Published: February 2022

Commercial propagation of pequizeiro, which stands out among the main native fruits of the Cerrado region for its high economic potential, has been done by seeds, despite their erratic germination. The objective of this study was to evaluate the effect of seed size and presence of thorns on the endocarp on seedling emergence of pequizeiro in the field. Seeds were collected in a pequizeiro commercial area in Canarana-MT, Brazil. Due to availability, 2,353 thorny seeds (3 sizes) and 106 seeds without thorns (medium sized) were tested. Thorny seeds were classified as large – longer than 50 mm; medium – between 40 and 50 mm; small – less than 40 mm. Seedling emergence started after 50 days in all seed categories, extending up to 100 days in the large seeds and to about 1 year after sowing in the small and medium sized ones. Small seeds showed a lower rate and speed of emergence compared to the others. Large seeds showed higher emergence speed compared to the medium ones. The presence of thorns did not affect seedling emergence. These results indicate the advantages of pequizeiro seed classification for sowing purposes.
Impact of reminder on medication adherence: a structural equation model, based on study in Sikkim, India
Authors: Saha Saibal Kumar , Jha Ajeya
Published: February 2022

The problem of medication non-adherence has persisted over decades. The rate of adherence decreases with time and improvement in health condition. When patients cannot follow their prescribed medication regime, it leads to deterioration of their health condition and increases their financial costs. This research aims to find the effect of reminder on medication adherence behaviour of patients when “Acceptance of Side Effect”, “Quality of Life” and “Medication Beliefs” act as mediators. The sample size of the research was 505. Sampling units comprised patients suffering from different diseases in Central Referral Hospital, Sikkim, India. By developing a Structural Equation Model, the effect of reminder on the mediators and adherence was analysed. The results show a significant positive association between reminder and the three mediators. Reminder has a significant positive effect on adherence (β=0.637, e=0.055, p=0.001). The effect is higher in the presence of mediators (β=0.7, e=0.037, p=0.001).
George D. Kilpatrick and the Textual Criticism of the New Testament: Three Variants from his Nachlass Discussed
Authors: Elliott James Keith
Published: February 2022

Among the unpublished papers by G.D. Kilpatrick written in the 1950s are the three notes printed here. They were prepared for BABELAO by J. Keith Elliott, who served as his literary executor. The notes concern textual variants at Mark 2:21; Hebrews 12:24 and Revelation 2:14. They contain Kilpatrick's suggested corrections of our printed editions there. It is to be hoped that these apparent minutiae will serve more widely as useful guides to all editors.
La mise en oeuvre de la cohérence pré-généalogique dans le cadre de la Coherence- Based Genealogical Method : évaluation critique
Authors: Pastorelli David
Published: February 2022

Alors que le texte alexandrin est généralement suivi dans les éditions du Nouveau Testament, la Coherence-Based Genealogical Method (= CBGM) revalorise de façon inattendue nombre de leçons byzantines dans l’Editio critica maior. Après un historique de la méthode et une présentation de la cohérence pré-généalogique, l’article offre une évaluation critique permettant de comprendre le dysfonctionnement de la cohérence pré-généalogique. Les critèresconstitutifs de la cohérence pré-généalogique sont tributaires autant de la forte homogénéité des témoins byzantins que de leur nombre pléthorique et ils génèrent de la sorte un biais en leur faveur, au détriment des autres types de texte. La revalorisation des leçons byzantines est de ce fait davantage provoquée par les critères adoptés par les promoteurs de la CBGM que par les sources elles-mêmes. La cohérence pré-généalogique est subordonnée aux accidents de la tradition manuscrite où le nombre de manuscrits conservés devient prépondérant. Sa prétention à statuer sur la façon dont a été copiée une leçon dans la tradition manuscrite n’est pas recevable. Notre évaluation montre qu’elle est en réalité réduite à détecter les leçons caractéristiques (ou non) d’un groupe textuel, tout en ignorant l’existence de groupe textuel autre que le texte byzantin. La CBGM se prévaut de conclure à une cohérence forte lorsqu’elle montre que les plus proches témoins partagent la même leçon, alors qu’elle n’aboutit en fait qu’à identifier la leçon caractéristique d’un type de texte. Or, le type de texte byzantin présentant l’homogénéité la plus forte en raison de ses pourcentages d’accords élevés, ses leçons caractéristiques ont immanquablement, selon cette approche, la cohérence la plus forte. Ainsi s’expliquent l’inéluctable revalorisation des leçons byzantines et le dysfonctionnement de la cohérence pré-généalogique.
An Overlooked Printed Peshitta New Testament from Germany after the Thirty Years War: Christian Knorr von Rosenroth’s Sulzbach Edition of 1684
Authors: Wilkinson Robert J.
Published: February 2022

This article discusses the provenance and purpose of an overlooked, and superficially rather uninteresting, edition of the Peshitta New Testament published by the Christian Kabbalist Christian Knorr von Rosenroth in Sulzbach in 1684. The text printed in square unvocalised Hebrew letters is most probably that of Plantin’s Antwerp Polyglot Bible, but its purpose is more obscure. By placing the edition in the context of precisely contemporaneous publications and tracing their use (in Latin) of the Syriac version, a picture is built up of Knorr’s development of a pedagogical programme facilitating the reading of the Syriac New Testament as expressing Zoharic doctrines in Zoharic language. An examination Knorr’s newlyrecovered last work, Messias Puer, displays the exegetical consequences of this in a close reading of the canonical New Testament text: a unique rapprochement of Christian and JewishKabbalistic doctrines.
Ivresse et société à Ougarit
Authors: Tavernier Jan
Published: February 2022

Cet article contient une étude sur le rôle que joue l’ivresse dans les textes d’Ougarit, ville littorale dans le nord-ouest de la Syrie. Après une introduction sur la bière et le vin à Ougarit en général, nous nous concentrons sur les expressions proche-orientales appartenant au champ sémantique de l’ivresse dans la langue ougaritique et sur les deux textes qui nous donnent plus d’informations sur l’ivresse et sur la façon comme elle fut perçue par les Ougaritains.
Analyse automatique du grec ancien par réseau de neurones. Évaluation sur le corpus De Thessalonica Capta
Authors: Kindt Bastien , Vidal-Gorène Chahan , Delle Donne Saulo
Published: February 2022

Le corpus DTC réunit des textes historiographiques grecs d’époque byzantine. Ces textes ont été analysés semi-automatiquement (lemmatisation et catégorisation morphosyntaxique) avec les outils informatiques et les ressources linguistiques du projet GREgORI (UCLouvain, Louvain-la-Neuve, Belgique) spécialisé dans le traitement automatique du grec et des langues de l’Orient chrétien. Une seconde analyse a été menée en collaboration avec l’entreprise Calfa (Paris, France) spécialisée dans le traitement de l’arménien et la mise en oeuvre d’approches basées sur l’intelligence artificielle. Cette seconde analyse est réalisée par un réseau de neurones. Cette étude compare et évalue les résultats produits par les deux méthodes et propose une approche hybride pour le traitement automatique des langues concernées.
Les centaures, Cerbère et leurs parents (non-)indo-européens (quelques notes sur les traces des contacts des Indo-européens au Proche Orient ancien)
Authors: Kulikov Leonid
Published: February 2022

Cet article se concentre sur l'origine de plusieurs mots étymologiquement obscurs des vocabulaires grec et indo-iranien (surtout sanskrit) (principalement des noms faisant référence à certaines divinités ou créatures de panthéons mythologiques inférieurs), tels que gr. κένταυρος / skr. gandharvá- et gr. Κέρβερος / skr. śábala- (l’un des deux chiens de l’enfer dans la mythologie indienne). Je suppose que ces formes ne peuvent être tracées à aucun étymon proto-indo-européen, mais, plutôt, sont empruntées à une ou plusieurs langues non indo-européennes du Proche-Orient, probablement membre(s) de la macro-famille du Caucase du Nord.
Adrien Reland, linguiste et orientaliste : deux contributions à la philologie comparée
Authors: Meyers Constance
Published: February 2022

Adrien Reland est un philologue du XVIIe siècle dont les contributions sont nombreuses et variées. Il s’agit ici d’évaluer la portée et l’originalité de ses apports dans le domaine du comparatisme linguistique et plus précisément dans celui de la parenté germano-perse. Il développe notamment une méthodologie visant à guider les étymologies et les rapprochements linguistiques, dont l’étude permettra d’évaluer la fiabilité du savant. Cet esprit systématique et prudent dont il fait preuve dans sa démarche se retrouve dans son catalogue de correspondances entre le perse et quelques langues européennes (latin, grec, slave, français, anglais, néerlandais). Il apparaît que ses comparaisons avec le slave, le latin et le grec comprennent des correspondances inédites.
Les tombes royales à partir de Mérenptah : réflexion sur deux figures liées au Livre de la Terre
Authors: Pleuger Léna
Published: February 2022

Les chambres funéraires royales à partir de Mérenptah présentent plusieurs motifs communs tel qu’un grand oiseau criocéphale dominant la paroi de ses ailes déployées. Sur la plupart des couvercles des sarcophages royaux de la période ramesside, le roi est représenté momiforme assimilé à Osiris et flanqué de serpents et d’un crocodile Cet article vise à éclairer la signification de ces deux motifs au regard du Livre des Cavernes et du Livre de la Terre dont certaines scènes ornent les parois de ces mêmes chambres funéraires.
FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN PERSEPSI TENAGA KESEHATAN TERHADAP VAKSIN COVID-19 DI PUSKESMAS X TAHUN 2020
Authors: Wulandari Denny , Heryana Ade , Silviana Intan , Puspita Erlina , H Rini , F Deasy
Published: February 2022

The importance of vaccination recommendations for health workers (HCWs) to the public is one of the strongest influencers in vaccination decisions. A preliminary study conducted on ten HCWs concluded that they had different perceptions of the COVID-19 vaccine. Different perceptions are influenced by functional function factors (age, gender, education), sociopsychological factors, and structural factors (knowledge, length of work). The aim of the study was to determine the factors related to the perception of HCWs on the COVID-19 vaccine. This type of research is cross sectional with a quantitative approach. The study was conducted in November 2020 - March 2021. The population and sample were 53 HCWs using total sampling method. Data analysis was performed using univariate and bivariate tests using the chi-square statistical test with α = 0.05. The conclusion shows that health workers with negative perceptions 22 people (41.5%), positive perceptions 31% (58.5%), young people 24 people (45.3%), old age 29 people (54.7%), 33 people (62.3%), 20 male (37.7%), 28 people (52.8%) poor knowledge, 25 good (47.2%), 14 new workyears (26.4%) and 39 long years of service (73.6%). The bivariate analysis showed that there was a relationship between health workers' perceptions of the COVID-19 vaccine with age (p value = 0.048, PR = 2.115), gender (p value = 0.029, PR = 2.727), knowledge (p value = 0.030, PR = 2,381). There is no relationship between perceptions of HCWs and years of service (p value = 0.286, PR = 1.592). It is hoped that agencies will provide more socialization and understanding and involve the active role of HCWs so that negative perceptions can be eliminated, considering that vaccine support from HCWs is urgently needed.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KELUHAN CARPAL TUNNEL SYNDROME (CTS) PADA PETUGAS OPERATOR PENGISI BBM DI SPBU KOTA KENDARI
Authors: Asfian Pitrah , Akifah Akifah , Jayandi Muh
Published: February 2022

Carpal Tunnel Syndrome disebabkan oleh beberapa faktor yaitu faktor okupasi seperti getaran, lama kerja, gerakan repetitif, postur kerja, dan masa kerja dan faktor non okupasi seperti riwayat penyakit, riwayat merokok, status gizi, umur, status kehamilan dan jenis kelamin. Salah satu jenis pekerjaan yang mempunyai aktivitas gerakan berulang dalam jangka waktu yang lama adalah operator pengisi Bahan Bakar Minyak (BBM) di Stasiun Pengisian Bahan Bakar Minyak (SPBU) ketika menekan nozzle. Penelitian ini bertujuan untuk mengetahui hubungan postur kerja, masa kerja, gerkan berulang, riwayat penyakit, dan status gizi dengan keluhan Carpal Tunnel Syndrome pada petugas operator pengisi BBM di SPBU Kota Kendari Tahun 2020. Jenis penelitian ini adalah penelitian analitik cross sectional menggunakan uji Chi-square dan Fisher's exact. Intrumen dalam penelitian ini adalah informed konsent, lembar hasil phalen test, lembar observasi rapid upper limb assesment, microtoise, boston carpal tunnel questionnaire, timbangan berat badan dan stopwatch. Sampel dalam penelitian ini sebanyak 64 orang dengan teknik pengambilan sampel proportional random sampling. Hasil penelitian ini terdapat hubungan antara postur kerja (ρ-value = 0,000), masa kerja (ρ-value = 0,012), gerakan berulang (ρ -value = 0,019), namun tidak terdapat hubungan antara riwayat penyakit (ρ -value = 0,188), status gizi (ρ -value = 0,544). Dapat disimpulkan bahwa postur kerja, masa kerja, gerakan berulang berhubungan dengan Carpal Tunnel Syndrome.
HUBUNGAN PENERAPAN POLA DIET DAN AKTIFITAS FISIK DENGAN STATUS KADAR GULA DARAH PADA PENDERITA DM TIPE 2 DI RSUD PETALA BUMI PEKANBARU TAHUN 2020
Authors: Santi Jasmiyul Sri , Septiani Winda
Published: February 2022

Kadar gula darah adalah jumlah atau konsentrasi glukosa yang terdapat dalam darah. Tingginya kadar gula darah dapat mengakibatkan berbagai komplikasi. Rumah Sakit Petala Bumi merupakan salah satu rumah sakit di Kota Pekanbaru. Berdasarkan data dari RS Petala bumi didapatkan bahwa jumlah pasien DM tipe 2 mengalami peningkatan, yaitu pada tahun 2017 sebanyak 75 pasien, tahun 2018 sebanyak 92 pasien dan tahun 2019 sebanyak 141 pasien. Tujuan penelitian ini yaitu untuk  mengetahui hubungan penerapan pola diet dan aktifitas fisik terhadap status kadar gula darah pada penderita DM Tipe 2 di RSUD Petala Bumi Pekanbaru tahun 2020. Jenis penelitian ini adalah analitik kuantitatif dengan desain cross sectional. Populasi adalah pasien penderita DM tipe 2 di RSUD Petala Bumi pada tahun 2019 yaitu sebanyak 141 orang dengan jumlah sampel sebanyak 82. Penelitian ini dilakukan di RSUD Petala Bumi Pekanbaru pada bulan April-Juli tahun 2020. Pengambilan sampel dilakukan dengan metode consecutive sampling dengan pengumpulan data menggunakan kuesioner, wawancara dan penelusuran dokumen. Analisis data menggunakan chi-square. Hasil penelitian ini yaitu ada hubungan antara jumlah makanan (p value =0,004), jenis makanan (p value =0,001), jadwal makanan (p value =0,013), aktivitas fisik (p value =0,001) dengan kadar gula darah di RSUD Petala Bumi Pekanbaru. Saran yaitu diharapkan bagi penderita DM agar menjadikan penelitian ini sebagai bahan referensi dalam meningkatkan penerapan pola diet berupa 3J (jumlah, jenis, dan jadwal) dan aktivitas fisik agar status kadar gula darah dapat terkontrol pada pasien DM tipe 2 melalui kegiatan yang berada di klinik gizi dan perawatan rumah sakit.
Ermittlung der Materialdaten zur Simulation des Durchhärtens von Komponenten aus 100Cr6
Authors: Acht C. , Dalgic M. , Frerichs F. , Hunkel M. , Irretier A. , Lübben Th. , Surm H.
Published: February 2022

Kurzfassung

Der Sonderforschungsbereich 570 „Distortion Engineering – Verzugsbeherrschung in der Fertigung“ an der Universität Bremen hat sich als ein Ziel die Bestimmung signifikanter Einflussgrößen und Wechselwirkungen auf den Verzug über die gesamte Fertigungskette von ausgewählten Bauteilen gesetzt, um die wesentlichen Mechanismen der Verzugsentstehung zu identifizieren. In diesem Zusammenhang kommt der Simulation eine große Bedeutung zu, da hiermit die zeitliche Entwicklung der Vorgänge auch lokal im Bauteil analysiert werden können. Hieraus können dann die signifikanten Vorgänge der Verzugsentstehung abgeleitet werden.

Für die Simulation muss ein qualitativ hochwertiger Datensatz als Grundvoraussetzung angesehen werden. In der vorliegenden Arbeit wird daher über das Vorgehen sowie die Herausforderungen bei der Erstellung eines Datensatzes für den Wälzlagerstahl 100Cr6 berichtet. Als einschränkende Bedingung soll dieser Datensatz zunächst nur für die Berechnung einer durchgreifenden martensitischen Härtung bei einem definierten Austenitisierungszustand gelten. Neben den thermophysikalischen und -mechanischen Kenngrößen werden die Parameter zur Beschreibung einer martensitischen Umwandlung angegeben.

Die Güte des erstellten Datensatzes wird aus dem Vergleich von berechneten und experimentell ermittelten Ergebnissen hinsichtlich Maß- und Formänderungen sowie der Eigenspannungen von Wälzlagerringen nach einer martensitischen Härtung diskutiert. ▪
Mathematische Ansätze zur Materialabtragsmodellierung beim Polieren
Authors: Loresch I. , Schulte H. , Riemer O. , Maaß P. , Dollinger F.
Published: February 2022

Kurzfassung

Aufgrund der immer höheren Anforderungen an die Formgenauigkeit bei optischen Flächen mit komplexen Geometrien (z. B. Freiformflächen für Head-Up-Displays) ist es notwendig, beim deterministischen Polieren auf einer Werkstückfläche lokal vordefinierte Abträge zu erzielen, wodurch eine minimale Formkorrektur bei gleichzeitiger Verringerung der Oberflächenrauheit erreicht wird. Aus diesem Grund bedarf es einer präzisen Steuerung des Polierwerkzeuges. Eine Möglichkeit hierfür ist, das Werkzeug und damit verbundene Materialabträge über Verweilzeiten zu steuern.

In diesem Beitrag wird das mathematische Problem der Ermittlung einer optimalen Verweilzeitverteilung aus der Fehlerfunktion des Werkstücks und der lokalen, im Prozess konstanten Materialabtragsfunktion des Werkzeugs diskutiert. Hierzu wird eine numerische Annäherung präsentiert, die stabil, sehr schnell und hinreichend genau das Optimum berechnet. ▪
Power enhancement of transformer less single-phase grid connected solar-wind energy conversion system for various environmental conditions
Authors: Kishore P S V , Jayaram Nakka , Rajesh Jami
Published: February 2022

This article presents the grid connected hybrid solar-wind energy conversion system (HSWECS) using the cascaded diode clamped multilevel inverter (CDCMLI). The advantage of CDCMLI over the conventional cascaded H-bridge multilevel inverter (CHBMLI) is that the power transfer capacity of the CDCMLI is doubled. The solar and wind energy conversion systems are connected individually to the DC-links of CDCMLI through the DC–DC converter which is used to get maximum power from solar and wind systems. Due to the fluctuating power supply by renewable sources, the isolated DC-links of separate inverters suffer from varying DC-link voltages. A control scheme is proposed which is capable of balancing these DC-link voltages under various power generation scenarios, extracting the maximum possible power from renewable energy sources (RES), and injecting it into the grid at near unity power factor. The proposed control also monitors the power quality of the injected current into the grid. Furthermore, it allows the system to be connected to the grid without any transformer. In addition, mathematical modeling of the CDCMLI has been presented. The performance of the system is analyzed with Matlab/Simulink and confirmed by a prototype model with dSpace 1104.
Perinatal bereavement care during COVID-19 in Australian maternity settings
Authors: Boyle Frances M. , Horey Dell , Dean Julie H. , Lohan Aditi , Middleton Philippa , Flenady Vicki
Published: February 2022

Objectives

Perinatal bereavement care is a complex area of practice. The COVID-19 pandemic led to reconfiguration of maternity and perinatal bereavement care services. This study explores Australian health care providers’ perspectives of the impact of COVID-19 on the provision of respectful and supportive care following stillbirth or neonatal death.

Methods

Members of a perinatal bereavement care network were consulted at the commencement of the pandemic in Australia using an online feedback form. Respondents provided ratings and free-text comments on the impact of COVID-19 on implementation of 49 recommendations contained in the Perinatal Society of Australia and New Zealand/Stillbirth Centre of Research Clinical Practice Guideline for Respectful and Supportive Perinatal Bereavement Care.

Results

Responses were received from 35 health care providers who provided perinatal bereavement care in clinical settings or through support organisations in Australia. Major impacts of COVID-19 were reported for 8 of 49 guideline recommendations. Impacts included reduced: support for mothers due to visitor restrictions; availability of cultural and spiritual support and interpreters; involvement of support people in decision-making; options for memory-making and commemorative rituals; and staff training and supervision. Adaptations to minimise impacts included virtual consultations, online staff training, use of cold cots, and increased staff support for memory-making.

Conclusions

Health care providers encounter substantial challenges as they strive to implement best practice perinatal bereavement care in pandemic conditions. Some practice adaptations developed during the COVID-19 pandemic could benefit parents; however, evaluation of their effectiveness and acceptability is needed.
Cardiac contractility modulation ameliorates myocardial metabolic remodeling in a rabbit model of chronic heart failure through activation of AMPK and PPAR-α pathway
Authors: Zhang Feifei , Liu Litian , Xie Yuetao , Wang Jiaqi , Chen Xuefeng , Zheng Shihang , Li Yingxiao , Dang Yi
Published: February 2022

Metabolic remodeling contributes to the pathological process of heart failure (HF). We explored the effects of cardiac contractility modulation (CCM) on myocardial metabolic remodeling in the rabbit model with HF. The HF in rabbit model was established by pressure uploading and then CCM was applied. We evaluated the cardiac structure and function by echocardiography, serum BNP level, and hematoxylin and eosin and Masson’s trichrome staining. We detected the accumulation of glycogen and lipid droplets in myocardial tissues by periodic acid-Schiff and Oil Red O staining. Then, we measured the contents of glucose, free fatty acid (FFA), lactic acid, pyruvate, and adenosine triphosphate (ATP) levels in myocardial tissues by corresponding kits and the expression levels of key factors related to myocardial substrate uptake and utilization by western blotting were analyzed. CCM significantly restored the cardiac structure and function in the rabbit model with HF. CCM therapy further decreased the accumulation of glycogen and lipid droplets. Furthermore, CCM reduced the contents of FFA, glucose, and lactic acid, and increased pyruvate and ATP levels in HF tissues. The protein expression levels related to myocardial substrate uptake and utilization were markedly improved with CCM treatment by further activating adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor-α signaling pathways.