bluuebunny/crossref_metadata_2025 huggingface dataset:
Omalgia crónica e associação com incapacidade funcional e ansiedade/depressão: a realidade de cinco Unidades de Saúde Familiar da Área Metropolitana do Porto
Authors:   Médico de Família, Machado Ana Catarina Sá , Martins Cláudio Sousa ,   Médico de Família, Ferreira Joana M. ,   Médico de Família, Santos Rita Sampaio ,   Médico de Família, Marçalo Sofia ,   Médico de Família, Vale Sofia ,   Médico de Família
Published: November 2020

Objetivos: Estimar a prevalência da omalgia crónica na população de cinco Unidades de Saúde Familiar (USF), descrever as suas características semiológicas e as características sociodemográficas desta população. Secundariamente pretende-se avaliar e quantificar a associação entre omalgia crónica e incapacidade funcional, características sociodemográficas e a perturbação ansiosa/depressiva. Tipo de estudo: Observacional, transversal, analítico. Local: Cinco USF da Área Metropolitana do Porto. População: Calculou-se uma amostra de 1.718 utentes entre os 18 e 64 anos, que se deslocaram às cinco USF durante o estudo. Métodos: Aplicou-se um questionário de recolha de variáveis sociodemográficas e sobre omalgia crónica e duas escalas validadas para a população Portuguesa: Health Assessment Questionnaire-Disability Index e Hospital Anxiety and Depression Scale. Testou-se a associação entre omalgia crónica, incapacidade funcional e ansiedade/depressão através do modelo de regressão logística multinomial. Resultados: A prevalência estimada de omalgia crónica foi de 29,6%, intervalo de confiança de 95% 27,4-31,8. Em 57,8% dos utentes a dor era diária, 70,7% tinha dor moderada a intensa e 41,1% encontrava-se pouco ou nada satisfeito com o tratamento. Verificou-se uma associação entre a existência e localização da dor com o estado emocional, género, estado civil, escolaridade, reforma e reforma por invalidez (p<0,001). Nos indivíduos com omalgia crónica, as mulheres, divorciados e viúvos, com baixa escolaridade, reformados por invalidez e com ansiedade/depressão apresentaram uma proporção superior. Constatou-se a existência de um aumento do odds ratio (OR) de omalgia crónica com o aumento do grau de incapacidade, da ansiedade, da idade e com a baixa escolaridade (inferior ou igual a nove anos). Conclusões: Apesar de prevista uma prevalência de omalgia crónica em Portugal de 4,4% com base em dados bibliográficos, a prevalência encontrada neste estudo foi aproximadamente sete vezes superior à esperada. Verificou-se uma associação da omalgia crónica com o grau de incapacidade e a ansiedade, o que vai de encontro ao debatido na literatura. O presente estudo mostra uma necessidade urgente de intervir eficazmente no controlo da omalgia crónica.
Predictive Analysis of Taxi Fare using Machine Learning
Authors: Banerjee Pallab , Kumar Biresh , Singh Amarnath , Ranjan Priyeta , Soni Kunal
Published: November 2020

This research aims to study the predictive analysis, which is a method of analysis in Machine Learning. Many companies like Ola, Uber etc uses Artificial Intelligence and machine learning technologies to find the solution of accurate fare prediction problem. We are proposing this paper after comparative analysis of algorithms like regression and classification, which are useful for prediction modeling to get the most accurate value. This research will be helpful to those, who are involved in fare forecasting. In previous era, the fare was only dependent on distance, but with the enhancement in technologies the cab’s fare is dependent on a lot of factors like time, location, number of passengers, traffic, number of hours, base fare etc. The study is based on Supervised learning whose one application is prediction, in machine learning.
State-Level Students Grievance Support System
Authors: Venkatesan Satheeswaran , R Arjun , A Nidhin , C. N2 Pranav
Published: November 2020

Students are the essential factor in an organization. The Scholar may feel dissatisfied with the service when he or she receives the delay of services. To beat this, we offer an optimized solution for the student grievances support system for improving the relationship between student and university by representing the model of e-complaint web-based system. The prevailing system has manual processing through committee, principal, head of department and college premises. This project overcomes the restrictions of the existing systems of complication of submitting a complaint and organizing it and it'll be a State-level support system. The proposed model is that the student has the ability to post a complaint easily and specifically using categories through our application and therefore the Admin are often ready to sort complains by supported keywords since the web application involves the utilization of keywords that are Students, Committee, Principal, University and Campus Which can be help us to provide the update data information through internet and It will helps to overcome the time process in an efficient way by acquire, store and process the data.
A Review on Some Classification Methods of Brain Tumor MRI Datasets
Authors: Mungale Nirmal , Kene Snehal , Chaudhary Amol
Published: November 2020

Brain tumor is a life-threatening disease. Brain tumor is formed by the abnormal growth of cells inside and around the brain. Identification of the size and type of tumor is necessary for deciding the course of treatment of the patient. Magnetic Resonance Imaging (MRI) is one of the methods for detection of tumor in the brain. The classification of MR Images is a difficult task due to variety and complexity of brain tumors. Various classification techniques have been identified for brain MRI tumor images. This paper reviews some of these recent classification techniques.
Improvement in K-medoid Clustering using Density based Node Selection
Authors: Kumar Biresh , Banerjee Pallab , Singh Amarnath , Kumar Anurag , Kumar Avinash
Published: November 2020

The wireless sensor networks have become a very hot topic of research in the recent years because of their wide range of applications such as industrial and agricultural monitoring, military surveillance, smart homes etc. These sensors can also be used in locations that are potentially hazardous to the human beings or are just out of our reach at this moment of time.
A wireless sensor network is collection of large number of individual sensor nodes. A sensor usually comprises of components for sensing the environment, processing, communicating and a power supply. The major limiting factor of the wireless sensor networks is the limited amount of power that each of the sensors can carry and also the energy in these sensors cannot be replenished easily. So, the major design challenge in a wireless sensor network has always been about reduction in the consumption of energy by the sensors. Clustering is one of the popular methods to reduce energy consumption in wireless sensor networks. Here, we propose a scheme to decrease the energy consumption and prolong the lifetime of wireless sensor network. The main idea behind the scheme is that we try to minimise the communication distance between the individual sensor nodes using the clustering technique.
Optimize Network Infrastructure using Architecting and Protocols
Authors: Suthar Parth , Kakadiya Romit , Dhameliya Mitul , Dangashiya Dhruv , Bhinasara Rutvik
Published: November 2020

This paper focuses on designing and optimize network infrastructure using different techniques. Nowadays most people and organizations use the internet, so the main problem is how to connect reliable and efficient ways to manage clients. Using networking fundamentals and techniques to reduce traffic and optimize network infrastructure on the small organization. We provide an optimal solution for small and start-up organization so they can effort own devices instead of renting servers and routers.
Tool to Integrate Optimized Hardware and Extensive Software into Its Database to Endure Big Data Challenges
Authors: S V N Madupu Kiran Kumar
Published: November 2020

Data is regarded a powerful raw material that can affect multidisciplinary study undertakings in addition to federal government as well as service performance. The goal of this discussion paper is to share the data analytics viewpoints as well as viewpoints of the writers connecting to the new opportunities and also challenges brought forth by the big data movement. The writers bring together varied viewpoints, originating from different geographical places with various core research study knowledge and also different associations and job experiences. This paper supplies a tool to integrate maximized equipment as well as extensive software right into its database to sustain big data difficulties.
Language To Language Translation System
Authors: Pratheeksha Ms , Rai Pratheeksha , Vijetha Ms
Published: November 2020

The system used in Language to Language Translation is the phrases spoken in one language are immediately spoken in other language by the device. Language to Language Translation is a three steps software process which includes Automatic Speech Recognition, Machine Translation and Voice Synthesis. Language to Language system includes the major speech translation projects using different approaches for Speech Recognition, Translation and Text to Speech synthesis highlighting the major pros and cons for the approach being used. Language translation is a process that takes the conversational phrase in one language as an input and translated speech phrases in another language as the output. The three components of language-to-language translation are connected in a sequential order. Automatic Speech Recognition (ASR) is responsible for converting the spoken phrases of source language to the text in the same language followed by machine translation which translates the source language to next target language text and finally the speech synthesizer is responsible for text to speech conversion of target language.
Palm Vein based Authentication
Authors: Banu Zaheema , S Rajesh D , G Sheethal
Published: November 2020

The palm vein authentication technology offers a high level of accuracy. Palm vein authentication uses the vascular patterns of an individual’s palm as personal identification data. If we compare with a finger or the back of a hand, a palm has a broader and more complicated vascular pattern and thus contains a wealth of differentiating features for personal identification. The importance of biometrics in the current field of Security has been depicted in this work. We have processed the raw image from the dataset before implementing authentication algorithm. After getting the suitable image after pre- processing, we have used local binary pattern (LBP) for feature extraction purpose & then using a machine learning algorithm, with support vector machine (SVM), we tried to match the vascular vein pattern for authentication. Result of the matching algorithm is not only optimized as per the proposed approach but also quite efficient.
Candidate Feature Extraction and Categorization for Unstructured Text Document
Authors: P Shelke Prajakta , A Pardeshi Aditya
Published: November 2020

In the phrases words contains crucial information which helps in feature extraction process. The established techniques for such has huge problem and has limitations in feature extraction process and also it ignores the grammatical structure for the phrases. So results as poor features get extracted. So to overcome this problem a system is proposed which is based on generation of parse tree for the input sentence and cut down into sub-tree subsequently. The branches of the tree are extracted using part-of-speech (POS) labelling intended for candidate phrase. To stay away from redundant phrases filtering is recommended. Finally machine learning is used for the Feature categorization progression. The result illustrates the effectiveness of the approach.
Factors Impacting Students Academic Performance Using R Code Programming Language for Analysing the Data
Authors: Fatimat. O Adesina , Ademola Akande , Abiodun. L Ajala , Tolulope Kolawole , Tajudeen. O Ogundeji
Published: November 2020

This work intends to investigate and propose a model that can be used by students, parents, teachers and education policy makers to understand and predict high school student academic performance based on pre-defined factors identified as capable of impacting students’ academic performance. This study uses ex post facto research design. An instrument measuring students’ academic performance has been used to collect data from the management students and R-Code programming language was used to analyse the data collected and there was a positive and statistically significant impact of learning facilities, age, romance and proper guidance from parent on student performance.
Ethanol and Methanol Levels in The Oplosan Liquor
Authors: Purwanti Angki , Aryadnyani Ni Putu
Published: November 2020

Oplosan liquor is one form of illegal drink that is often found in police raids in various areas. The purpose of this study was to determine the ethanol and methanol levels in mixed liquor obtained from the results of the Sector Police raids in Cipayung District, East Jakarta, in 2017. This study was a cross-sectional descriptive study. Determination of ethanol and methanol levels is done by gas chromatography at the Daerah Khusus Ibukota Jakarta Health Laboratory. The sample in this study amounted to 14 samples. Based on the research obtained Ethanol content from test material (10.08-50.14)% v/v with an average (28,39±15,09)% v/v and methanol content is (0.08-2.04)% v / v with an average of (0,81±0,72)%v/v. Samples whose ethanol content is equivalent to alcoholic groups A, B, and C are 0%, six bottles (42.86%), and eight bottles (51.13%). All samples contained methanol with levels> 0.01% and were not packaged according to the requirements of the Regulation of the Indonesian Food and Drug Supervisory Agency No. 14/2016 (BPOM). It is suggested to do a follow-up in counseling related to mixed alcohol, especially for adolescents in this area. Further research is suggested to identify illegal drugs in the confiscated alcoholic drinks from this area. It is recommended to the Cipayung District Police to clean the area from mixed alcohol.
Produksi Asam Laktat dari Fermentasi Limbah Cair Olahan Kelapa dengan Variasi Konsentrasi Inokulum Lactobacillus acidophilus
Authors: Ratna Ratna , Triovanta Ulfa , Darwin Darwin
Published: November 2020

The aim of this research is to study the fermentation technique of coconut processed liquid waste by varying the inoculum concentration of Lactobacillus acidophilus bacteria for lactic acid production. This research was carried out in several steps, namely the first step was the inoculum cultivation process of Lactobacillus acidophilus bacteria, the second step was the fermentation process of coconut water with variations in the concentration of Lactobacillus acidophilus bacteria inoculum, namely 5%, 10% and 20%. Analysis of lactic acid products, pH, glucose, Total Dissolved Solid (TDS), Total Suspended Solid (TSS) and Volatile Suspended Solid (VSS). The variation in the concentration of Lactobacillus acidophilus bacteria inoculum 20% is the most optimum to produce total lactic acid for batch and continuous systems. The results of the correlation analysis for inoculum variations of 5%, 10% and 20% had a strong relationship with lactic acid production, decreased pH and decreased glucose levels. The greater the inoculum concentration, the greater the decrease in the TDS, TSS and VSS content.
Nota Penyelidikan/Research Notes Penyertaan Agama Warga Tua Rumah Seri Kenangan Malaysi
Authors: ISMAIL ZAINAB , WAN AHMAD WAN IBRAHIM , TIBEK SITI RUGAYAH , ENDOT IDERIS , MD. SHAM FARIZA
Published: November 2020

Kajian lepas menunjukkan penyertaan warga tua dalam aktiviti agama boleh mengurangkan aspek negatif yang banyak dalam kehidupan mereka, seperti kemurungan (Kennedy, Howard, Cynthia & Jiming, 1996), atau meningkatkan kepuasan hidup (Quadagno, 1999), memberikan makna dalam kehidupan (Elmi Baharuddin, 2008), dan kebanyakan warga tua menganggap agama penting dalam kehidupan (Wan Ibrahim Wan Ahmad, 2008). Kajian-kajian ini, kecuali kajian Elmi Baharuddin, dilakukan ke atas warga tua dalam komuniti, bukan warga tua yang tinggal di Rumah Seri Kenangan. Banyak persoalan boleh ditimbulkan tentang penyertaan warga tua yang tinggal di Rumah Seri Kenangan dalam aktiviti agama. Tidak ada jawapan yang jelas yang boleh diutarakan tentangnya. Maklumat dalam nota penyelidikan ini diambil daripada hasil awal projek penyelidikan dengan Kod Projek: UKM-PP-04-FRGS0005-2006/04, bertajuk “Penyertaan Agama, Konsep Kendiri dan Keperluan Kaunseling Warga Tua Rumah Seri Kenangan di Malaysia”. Kajian tersebut bertujuan menganalisis penyertaan warga tua dalam amalan agama, mengenal pasti konsep kendiri warga tua dan mengenal pasti indikator yang menunjukkan warga tua memerlukan perkhidmatan kaunseling di Rumah Seri Kenangan. Tumpuan penyelidikan itu adalah ke atas warga tua yang tinggal di Rumah Seri Kenangan (RSK). Warga tua ialah individu yang berumur 60 tahun dan ke atas. Pengertian ini berasaskan resolusi Perhimpunan Dunia Bangsa- Bangsa Bersatu World Assembly on Aging yang pertama tentang penuaan yang diadakan di Vienna pada tahun 1982. Dalam perhimpunan tersebut, umur “60 tahun dan lebih” digunakan sebagai had umur dalam menentukan trend penuaan, walaupun kebanyakan negara maju menggunakan had umur 65 tahun dan lebih dalam menentukan trend penuaan mereka.
Effects of Psychoeducational Group on Muslim Spouses’ Communication
Authors: AHMAD ROSLIZA , HASSAN SITI AISHAH
Published: November 2020

Statistics released by Jabatan Kemajuan Islam Malaysia (JAKIM) shows that the marital conflict and divorce rates among Muslim increases every year. There are a range of factors associated with marital conflict and divorce. In present study communication is highlighted as the factor that contribute to marital conflict and divorce among Muslim spouses. In an effort to help spouses manage and overcome marital conflicts, Muslim spouses need for an Islamic base according to the religious perspective. For that purposes this article is an attempt to examine the effects of psychoeducational group known as Marital Psycho-Spiritual Intervention (MP-SI) on communication among Muslim husbands and wives at Felda in Kedah. A psychoeducational group is a systematic effort to help improve the functioning of Muslim spouses’ communication through education and preventative means which widely used in guidance and counseling services. It is a group approach conducted by marriage counselors to educate and disseminating knowledge and skills related to marriage relationships. The randomized controlled trials (randomized control group design with pretest, posttest and follow up test) was used in this study. The experimental and control group of this study was totally composed of 76 participants, 38 in experimental group and 38 in control group. Participants in experimental group received a treatment of MP-SI for 6 weeks (2 hours per week). Marital Communication Inventory (MCI) was utilized to obtain the data for communication in three times (pretest, posttest, and follow up). A Mixed Between-Within Subjects ANOVA was used to see the differences between the mean scores of pretest, posttest, and follow up test within both experimental and control group. The results from mixed between-within subjects ANOVA showed that there were a statistically significant main effect of time and group for communication. Participants in the experimental group showed improvement in communication compared to the control group over the three time periods. These findings demonstrated the MP-SI conducted in this study had a higher impact on the experimental group and the effect was similar on the male and female participants. These results reveal valuable information that an Islamic psycho-spiritual approach that emphasizes the spiritual practices and element of nafs (soul), aql (intellect), qalb (heart), and ruh (spirit) help improve Muslim spouses’ communication.
Kembalinya Kak Jun: Pengalaman Penghijrahan Seorang Mak Nyah
Authors: ELIAS NADIYAH , MUBARAK ALI NURHIKMAH
Published: November 2020

This article is about a life story of a Muslim individual who has experienced gender identity disorder and follows his journey back to the Islamic way of life. Going by the nickname of “Kak Jun”, he has been experienced gender identity disorder since primary school, which has led him to deviate from the Shari’a law. from middle school to adulthood. Kak Jun has now completely returned to the Shari’ah compliant lifestyle, and he is actively preaching to the transgender community. This study focuses on the factors that motivate Kak Jun to work towards returning to a pattern of sharia-compliant life. These factors can be used to help counselors formulate effective Islamic approaches to helping these special populations be either at the level of development, prevention or recovery.
Love Scam di Selangor: Satu Penerokaan terhadap Modus Operandi Jenayah Siber ke atas Wanita Profesional
Authors: ALAVI KHADIJAH , SOOED MOHAMMAS SYAHRUL AZHA , BAKAR AL-AZMI
Published: November 2020

Love Scam is a cyber or commercial crime targeting women, especially professional women’s who have lost millions of ringgit in Malaysia. This study explores the factor of victim involvement and modus operandi used by the scammer. The interviews were conducted at the District Police Headquarters (IPPD) in Selangor. A total of five love scam victims were interviewed, with the assistance of police officers dealing with commercial crime cases. The findings show that prominent factors identified are the perpetrators sweet talk, socializing, easy internet access and self pressure among victims. The modus operandi often used by the perpetrators to trap victims is through fraud profile picture in social media, fake sweet promises, and packaged delivery and posing as representatives of tax agencies.
The role of vocational education in developing entrepreneurial competences of students
Authors: Perić Julia , Oberman Peterka Sunčica , Getoš Željka
Published: November 2020

Entrepreneurship is defined as one of key lifelong competences and it represents ability to turn ideas into real projects. As such, it includes creativity, initiative, taking responsibility, taking risks, planning and managing projects. The development of entrepreneurial competences via formal education has become a priority for governments of a large number of European countries. Many EU documents emphasize the importance of investing into education that focuses on the development of entrepreneurial competences, as it directly affects students’ employment. However, this guideline represents a new challenge for the educational system – the need to change educational programs and organize them so that they influence the development of entrepreneurial competences, which enables students to become more employable and to cope with uncertainty, complexity and dynamics of the labor market. High unemployment rate of young people and challenges and demands of the labor market have led to a debate about the effectiveness and efficiency of educational programs at all levels. In this context, effectiveness and quality of vocational education and training (VET) are particularly important, since most vocational school students, after finishing secondary level, will not continue towards tertiary education, but will rather find themselves on the labor market. Therefore, vocational education should focus on the development of such skills (generic competences and vocational qualifications) that will correspond to the needs of the labor market, thus enabling easier and faster employment. The main purpose of this paper is to determine the extent to which vocational education contributes to development of students’ entrepreneurial competences. The data used in this paper comes from a survey that covered 1272 students from 15 secondary vocational schools in Osijek-Baranja County, one of the most underdeveloped regions in Croatia. The analysis of the results has shown that there is a positive correlation between extracurricular activities and entrepreneurial environment with the level of students’ entrepreneurial competences. No correlation between the formal educational program and the level of entrepreneurial competences has been found. The findings of this research may serve as the basis for the development of vocational education programs that would include and meet the labor market demands, thus increasing students’ employability.
Media education in the school system
Authors: Walat Wojciech
Published: November 2020

The diagnosis of the problem of the contemporary world in the area of global media communication is a basic challenge for existing and modernized educational systems. Without a complete vision of the world, people cannot exist in a fully aware way. Hence, the most important questions related to such social development in which no one would be excluded from the world-wide circulation of information. The general assumptions of common media education have been presented in the article.
Mener l'enquête. Arts de faire, stratégies et tactiques d'investigation de journalistes
Authors: Labarthe Gilles
Published: November 2020

A travers une approche socio-ethnographique liant observation participante, entretiens semi-directs et récits de pratiques, ce livre propose d'étudier en détail l’évolution récente des «arts de faire» de l’enquête que les journalistes mobilisent, en tant qu’acteurs sociaux inscrits dans les relations triangulaires entre médias, pouvoirs (politiques, institutionnels, économiques...) et public.

L'auteur montre que les professionnel·le·s de l’investigation journalistique entretiennent une «nécessaire indétermination» autour de leurs pratiques. Ils recourent à des techniques d’enquête implicites, mouvantes et créatives; ceci, à la fois pour remédier aux désavantages d’une position précaire (manque de budget, de moyens...), pour contourner des problèmes d’accès aux informations gouvernementales, pour échapper à des tentatives de prise de contrôle sur leurs activités ou encore, plus récemment, pour déjouer les risques liés à la cybersurveillance.

Gilles Labarthe propose de nouveaux éléments de compréhension sur le journalisme d’investigation et ses enjeux actuels, un champ de recherche qui n'avait encore jamais été exploré de manière approfondie en Suisse, sous cet angle. Il apporte aussi de nouvelles notions et des clés de lecture concernant la déontologie et les «fondamentaux» du métier, utiles aux cursus de formation professionnelle.
Coaching to Tackle COVID-19 Crisis: A Critical Review for Management Practitioners
Authors: Khalid Nadeem , Islam Dewan Md Zahurul
Published: November 2020

The current paper is an attempt to refresh the concept of coaching in the minds of scholars to help them address major issues affecting performance, psychological well-being, and behaviors of employees due to the COVID-19 Pandemic. The paper serves as an effort to help organizational researchers recall the concept of coaching and its benefits for people and their organizations during the current times. The work also aspires to encourage researchers to consider investigating coaching to provide objective results for policy and implications. The article provides information on the idea of coaching and the various explanations given by management and organizational practitioners. The paper also provides information on the purpose of coaching and why organizations need to understand the concept of coaching and the different types that are available both within and outside of the organizations. Important to state that the paper also discusses the benefits of coaching, which spotlights the need for coaching to be utilized by organizations. Lastly, the paper discusses how coaching can be particularly important in crises like COVID-19 Pandemic followed to guide and recommend organizations to make the use of it to overcome employee, organization, and performance-related issues.
PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia
Authors: Li Jessica , Whelan Sarah , Kotturi Maya F. , Meyran Deborah , D’Souza Criselle , Hansen Kyle , Liang Spencer , Hunter John , Trapani Joseph A. , Neeson Paul J.
Published: November 2020

This study explored the novel immune checkpoint poliovirus receptor- related immunoglobulin domain-containing (PVRIG) in acute myeloid leukemia (AML). We showed that AML patient blasts consistently expressed the PVRIG ligand (poliovirus receptor-related 2, PVRL2). Furthermore, PVRIG blockade significantly enhanced naural killer (NK)-cell killing of PVRL2+, poliovirus receptor (PVR)lo AML cell lines, and significantly increased NK-cell activation and degranulation in the context of patient primary AML blasts. However, in AML patient bone marrow, NK-cell PVRIG expression levels were not increased. In order to understand how PVRIG blockade might potentially be exploited therapeutically, we investigated the biology of PVRIG and revealed that NK-cell activation resulted in reduced PVRIG expression on the cell surface. This occurred whether NK cells were activated by tumor cell recognition, cytokines (interleukin 2 [IL-2] and IL-12) or activating receptor stimulation (CD16 and NKp46). PVRIG was present at higher levels in the cytoplasm than on the cell surface, particularly on CD56bright NK cells, which further increased cytoplasmic PVRIG levels following IL-2 and IL-12 activation. PVRIG was continually transported to the cell surface via the endoplasmic reticulum and Golgi in both unstimulated and activated NK cells. Taken together, our findings suggest that anti-PVRIG blocking antibody functions by binding to surface-bound PVRIG, which undergoes rapid turnover in both unstimulated and activated NK cells. We conclude that the PVRIG-PVRL2 immune checkpoint axis can feasibly be targeted with PVRIG blocking antibody for NK-mediated immunotherapy of PVRL2+ AML.
The Effects of Gavage Extract of Papaver Rhoeas L on Blood Pressure of MIA Induced Osteoarthritis and Its Interaction with Nitrergic System in male Rat
Authors: Sangy Sareh , Miryousefiata Faeghe , Bahaoddini Aminollah , Dimiati Herlina
Published: November 2020

Hypertension is one of the most common and most prevalent diseases in the world today. Chronic inflammation is one of the risk factors for cardiovascular disease (CVD). Since synovial inflammation plays a role in the initial stages of osteoarthritis (OA), therefore, the side effects of OA are the incidence of CVD. One of the most appropriate methods for treating this disease is the use of medicinal herbs that have a blood pressure modifying effect Due to OA as Papaver rhoeas. The present research shows The Effects of Extract of Papaver rhoeas on Blood Pressure of rats with OA and Its Interaction with nitrergic System. OA model in 35 male rats was created by injection of monosodium iodoacetate (MIA) into the right knee joint and then were gavaged with extract of Papaver rhoeas for 30 days.  On day 30, the veins and arteries of the animal were then cannulated for injection and measurement of blood pressure, respectively. Blood pressure parameters (systolic, diastolic, mean arterial pressure) were recorded in groups before and after L-NAME injection. The results were analyzed using SPSS software. Systolic, diastolic, and mean arterial pressure in response to extract of Papaver rhoeas was reduced compared to control(OA), as well as Significant decrease in systolic and diastolic pressure and mean arterial pressure and increased heart beat rate in the presence of extract and LNAME as compared with control group. (P <0/05) .We found that the aqueous extract of Papaver rhoeas has a decreasing effect on blood pressure in rats with OA. This effect may be due to inhibition of the nitrergic system.
The Analysis of Coalition Parties´ Election Programme Fulfillment: Czech Case Study
Authors: Kuba Ondřej , Stejskal Jan
Published: November 2020

In multi-party democratic systems, where there is no absolute majority, the political parties are forced to cooperate. The cooperation is built on negotiations that result in several side effects including also concessions and compromises in the program. This analysis focused on the fulfillment of the coalition party promises in the Czech Republic, specifically on Prime Minister Bohuslav Sobotka´s government. The input data of the research consisted of a prepared set of testable political promises from the pre-election programs of selected political parties. The promises were compared with the contents of the coalition agreement, the government’s policy statement. It was found that coalition political parties selected by the government within the framework of coalition cooperation managed to enforce approximately 36 % of their election promises. At the program level, 24 % of promises were enforced. In areas that increase the personal budget of voters, government political parties have pushed 76 % of promises. Regardless of their cooperation, they made approx. 52 % of the election promises during the parliamentary term. The dominant party of the government was the CSSD.
Quantitative Analysis Of Trace Metal In Water And Soft Tissues Of Balanus Amphitrite In Nandikadal Lagoon, Sri Lanka
Authors: Kuganathan Sivashanthini , Shivatharshini Yohi Dhanushka Dilini Jayaweera , Gunaalan Kuttithamby
Published: November 2020

Due to long–term military activities carried out in Nandikadal lagoon situated at Mullaitivu, Sri Lanka, there are high possibilities to impact water and biota with heavy metals. Balanus amphitrite (Barnacles) has been found as a strong candidate for biomonitoring of trace metals. Therefore, the present study describes the impacts of trace metal pollution on water and the soft tissues of Balanus amphitrite. Water samples and barnacles were collected from two locations of the lagoon for four months during the dry and wet seasons. Quantitative analysis of trace metals (Cd, Cu, Cr, Pb and Zn) were detected in the water and tissue samples using flame atomic absorption spectrometry. Cd, Cr, Pb and Cu found in tissues of barnacles were several times higher than the International recommended level except for Zn. The concentration of Pb in tissues of barnacles showed a significant (p < 0.05) spatial variation. The Cd and Cu concentrations obtained in soft tissues showed significant (p < 0.05) seasonal variations. The concentration of Cr in water showed a significant (p < 0.05) spatial variation and other trace metals (Pb,Cd) except Zn, showed significant (p < 0.05) seasonal variations. There were significant positive correlations between water and soft tissues with respect to Cd (p=0.000 & r = 0.893) and Pb (p=0.002 & r=0.435). Zn found in samples showed negative correlation between water and soft tissues. According to this results Balanus amphitrite has an ability to accumulate trace metals several times greater than in the lagoon water. Therefore, Balanus amphitrite is a strong net–accumulator of Cd, Pb, Zn, Cu, Cr. Hence, it is a good choice to be used as a bioindicator organism to find the level impact of trace metal contamination.
Coating as Micro-Structural System
Authors: Murčinková Zuzana , Murčinko Jaromír
Published: November 2020

The paper provides the application of nanostructured TiAlN and nanocomposite structured TiAlSiN coatings on step drills. The analyses proved that the obtained tool lives are different despite the fact that the same tool geometry, coating, and PVD (physical vapour deposition) technology are used. This disproportion was experimentally tested focusing on surface condition using the pre and post treatment and on the chemical and structural coating composition.
Crystallographic Orientation Effect On Hole Polar Optical Phonon Scattering Rates in Thin Gaas/Alxga1-Xas Quantum Wells
Authors: Boumaza Mohamed
Published: November 2020

We report on hole polar optical phonon scattering processes in thin GaAs/AlxGa1-xAs quantum wells grown in various crystallographic directions, such as [001], [110]. Using the dielectric continuum model we focus on how the different scattering processes of holes with interface phonon modes depend on the initial hole energy. In our work, we use the Luttinger-Kohn (LK) 6×6 k.p Hamiltonian with the envelope function approximation, from which we compute numerically the electronic structure of holes for a thin quantum well sustaining only one bound state for each type of hole. Due to mixing between the heavy, light, and split off bands, hole subbands exhibit strong nonparabolicity and important warping that have their word to say on physical properties. Detailed and extensive calculations that the rates for intra-subband scattering processes differ significantly from those of bulk GaAs because of quantization and reduced dimensionality. Moreover, the study of scattering as a function of hole energy shows that the trend of the scattering rates is governed mostly by i) overlap integrals and ii) the density of the final states to which the hole scatters. The influence of warping, in the hole energy dispersion, on the phonon scattering rates is also explored and found to be important when the initial hole energy is high. Our calculations show evidence of strong anisotropy in the scattering rates especially for processes involving the heavy hole subband, which anisotropy is in fact quite important and far from being negligible. However, strain effect can reduce scattering rates.
Impact of Material On Energy Efficiency of Distribution System
Authors: Hrabovský Peter
Published: November 2020

The article focuses on technologies that are closely linked to the use of renewable energy sources. We are living at a time when the emphasis is on increasing the share of production and use of heat and electricity generated by technologies using the sun, wind, water and earth. By transforming energy from sources like the Sun and the Earth, we use solar, photovoltaic collectors, heat pumps and circulation systems. Energy production in these ways is limited, therefore the research and development of individual systems is pushing the possibilities of using renewable energy sources forward. The main objective of obtaining energy from renewable sources is to cover the energy performance of buildings and people’s requirements to ensure optimal thermal comfort with maximum use of energy from renewable sources. When designing the required technologies, it is necessary to emphasize the choice of construction material for individual parts of the energy system. If we want to extract energy from the earth it is necessary to design a material suitable for aggressive soil environment – the Earth’s shell. The negative impact of soil chemical and physical properties affects not only the material structure of a part of the technology, but also the overall efficiency of the energy system.
Postural and craniocervical dysfunctions and their relationship to the voice of women with cervical pain
Authors: Silva Caroline Azevedo da , Frigo Letícia Fernandez , Santos Sabrina Silva dos , Cielo Carla Aparecida
Published: November 2020

Introduction: Altered body alignment may contribute to the onset of muscle hypertension in the cervical region. Alterations in the cervical region can generate several complications, including pain and hypertension during phonation. Objective: To relate the postural with functional alterations of the craniocervical region and the voice of women complaining of musculoskeletal pain in the cervical region. Methods: Case study with ten women complaining of cervical pain. Assessments: Craniocervical Dysfunction Index, photogrammetry, maximum vowel phonation time of the vowel /a/, and sound pressure level. Results: Craniocervical Dysfunction Index: 100% dysfunction. Maximum phonation time /a/: 100% decreased. There was a moderate significant positive correlation between these variables. Photogrammetry: all participants presented alterations in the calculated alignments. Sound pressure level: 90% altered. Conclusion: There were postural and functional dysfunctions in the craniocervical region and vocal alteration, suggesting that vocal imbalances are more related to functional than postural alterations of the craniocervical region.
Evidências científicas sobre intolerância à lactose: uma revisão de literatura
Authors: Silva Amanda Bruna da Costa , Araújo Kênnia Regina Santos , Carvalho Luiza Marly Freitas de
Published: November 2020

A intolerância à lactose tem como definição um transtorno que ocorre no trato digestivo, e isso acontece devido a pouca ou nenhuma produção de lactase pelo intestino delgado, suas manifestações variam de acordo com a quantidade de leite e derivados ingeridos. O objetivo do trabalho foi realizar uma revisão de literatura sobre evidências científicas relacionadas à intolerância à lactose. Para a seleção da amostra foram utilizados artigos em anexos nacionais do período de 2012 a 2020. A busca dos artigos foi realizada nas seguintes bases de dados eletrônicos: no repositório Scientific Electronic Library On-line (SciELO) e no portal/repositório Google Acadêmico. Empregando os descritores: “cálcio”, “intolerância à lactose” e “leite”, cadastrados nos Descritores em Ciência da Saúde (DeCS). Foram selecionados inicialmente 30 artigos que abordavam os descritores, que após análise do objeto de estudo e os critérios de inclusão e exclusão, restaram 9 artigos. Observou-se que a intolerância à lactose é uma patologia digestiva que afeta todas as idades, podendo levar a desordens no quadro do paciente, ocasionando uma insuficiência de micronutrientes, em especial o cálcio. Dessa maneira, conclui-se que é necessário à assistência aos pacientes, ou seja, os mesmos precisam de um acompanhamento nutricional para evitar maiores prejuízos ao seu estado de saúde, fazendo a suplementação de acordo com a necessidade de cada paciente para que se evite a toxicidade.
Análise in silico do perfil farmacocinético e toxicológico de fármacos em pesquisa para o tratamento da COVID-19
Authors: Bastos Kallyne Zilmar Cunha , Cortêz Andreza Huete da Silva , Cortêz Thalya Huet Carneiro , Pinto Ingrid Sousa , Sousa Joubert Aires de
Published: November 2020

A pesquisa em pauta tem como objetivo o fornecimento de informações sobre os medicamentos em estudo para o tratamento da Covid-19, além de elucidar dados dos parâmetros farmacocinéticos e toxicológicos que possam auxiliar na terapia do paciente acometido com o coronavírus, através de uma análise in silico. Para alcançar os objetivos propostos, utilizou-se de ferramentas in silico, empregando os softwares ACD/Chem Sketch (versão 14.0) e Marvin Sketch. A análise dos parâmetros farmacocinéticos e toxicológicos foi feita através do servidor PreADMET, que realiza a predição dos dados baseando-se na relação estrutura/atividade. Para complementar os dados coletados em ferramentas computacionais realizou-se um levantamento bibliográfico nas principais bases de dados sobre os parâmetros analisados. Conforme as análises dos resultados ADME os medicamentos abiraterona e brequinar são os que apresentam mais parâmetros farmacocinéticos desejáveis. Alguns dos medicamentos observados demonstraram respostas satisfatórias, em especial a cloroquina, que atendeu ao parâmetro de passagem na BHE, uma vez que o coronavírus vem causando manifestações no SNC, porém esta medicação está relacionada com o crescimento de mortes por arritmias. Já os parâmetros toxicológicos apresentam em sua maioria fármacos não mutagênicos e não carcinogênicos e, em relação ao hERG, a maioria classifica-se como médio risco. Os fármacos empregados no tratamento dos pacientes cardiopatas devem ser escolhidos cuidadosamente, pois alguns deles elevam o risco cardíaco. A ivermectina e a nitazoxanida apresentam metabólitos com potencial mutagênico, portanto, devem ser utilizados com cautela.
Cuidado educativo no ciclo gravídico-puerperal à luz da teoria de Paulo Freire: contribuições para assistência
Authors: Grossi Vanessa Cristina de Vasconcelos , Rocha Cristiane Rodrigues da , Vernaglia Taís Veronica Cardoso , Barbosa Márcia Neves
Published: November 2020

Objetivos: analisar as necessidades de orientações em saúde das gestantes sobre o ciclo gravídico-puerperal e discutir a educação em saúde realizada pelos profissionais de saúde no pré-natal à luz de Paulo Freire. Metodologia: pesquisa descritiva com abordagem qualitativa, realizada em um hospital universitário, de setembro a outubro de 2019, com 27 gestantes participantes. Os dados foram coletados por meio de uma entrevista por pauta e, posteriormente, submetidos à análise de conteúdo de Bardin. Resultados: após a análise, emergiram três categorias, sendo elas: as necessidades de orientações em saúde das gestantes acerca do gestar, do parir e do pós-parto; os conhecimentos populares das gestantes sobre o ciclo gravídico-puerperal; e a educação em saúde realizada pelos profissionais de saúde no pré-natal. Na análise das categorias, foi notória a observação de que a educação em saúde efetuada pelos profissionais de saúde não contemplou em sua totalidade as reais necessidades de orientações em saúde apresentadas pelas gestantes. Conclusão: a educação em saúde realizada pelos profissionais de saúde não deve ser impositiva, devendo haver uma relação dialógica que leve em consideração os aspectos socioculturais, psicológicos e biológicos das gestantes e de suas famílias, bem como os seus saberes preexistentes, a fim de ressignificá-los. Considera-se este meio fundamental, para que, com base no contexto de vida das gestantes, haja maior possibilidade de obtenção do impacto desejado da educação em saúde, o alcance da liberdade consciente e autônoma de escolhas das mulheres, a promoção da saúde e o autocuidado.
Cuidados de enfermagem no pós-operatório de cirurgia cardíaca
Authors: Santos Natalia Castaman dos , Lima Caio José Felix da Silva , Rosa Junior Silvio  Luiz Rocha , Silva Gabriela Fulan e
Published: November 2020

O presente estudo teve por objetivo identificar e avaliar os cuidados de enfermagem no pós-operatório de cirurgia cardíaca, procedimento de alta complexidade com importantes repercussões orgânicas, levando a um estado crítico pós-operatório e impondo cuidados intensivos para a recuperação do indivíduo. Trata-se de uma revisão integrativa da literatura realizada nas bases de dados Literatura Latino-americana e do Caribe em Ciências da Saúde, PubMed/MEDLINE e Excerpta Medica database. Foram incluídos estudos publicados em português, inglês e espanhol, entre 2009 e 2019 e que respondessem à pergunta norteadora. Entre os resultados encontrados, destaca-se a monitoração de parâmetros vitais, elaborações e implementações de planos de cuidados de enfermagem, uso de sistemas automatizados, uso de instrumentos padronizados e a importância da capacitação profissional para tal utilização. Essas evidências podem fornecer subsídios para a realização do processo de enfermagem e contribuir para a melhora da assistência dessa população.