bluuebunny/crossref_metadata_2025 huggingface dataset:
Outcomes of Trachelectomy vs. Hysterectomy for Early-Stage Cervical Cancer: A Systematic Review and Meta-Analysis
Authors: Guo Juan , Hu Qingwei , Deng Zaixing , Jin Xiaotian
Published: November 2021

Objective: To provide updated evidence on comparative efficacy for clinical outcomes of radical trachelectomy and radical hysterectomy in patients with early-stage cervical cancer.

Methods: A systematic search was conducted in the PubMed, Scopus, Cochrane Database of Systematic Reviews, and Google scholar databases. Studies were done in patients with early-stage cervical cancer that compared the outcomes between radical trachelectomy (RT) and hysterectomy (RH) were considered for inclusion in the review. The outcomes of interest were operative time, the volume of blood loss, need for blood transfusion, any complications, length of hospital stay, risk of recurrence, and survival. The strength of association was presented in the form of pooled relative risk (RR), hazards risk (HR), and weighted mean difference (WMD). Statistical analysis was done using STATA version 16.0.

Results: A total of 12 articles were included in the meta-analysis. The majority were retrospective cohort-based studies. Compared to RH, the operative time (in min) was comparatively higher in RT (WMD 23.43, 95% CI: 5.63, 41.24). Patients undergoing RT had blood loss (in ml) similar to those undergoing RT (WMD −81.34, 95% CI: −170.36, 7.68). There were no significant differences in the risk of intra-operative (RR 1.61, 95% CI: 0.49, 5.28) and post-operative complications (RR 1.13, 95% CI: 0.54, 2.40) between the two groups. Patients in the RT group had lesser duration of post-operative hospital stay (in days) (WMD −1.65, 95% CI: −3.22, −0.09). There was no statistically significant difference in the risk of recurrence (HR 1.21, 95% CI: 0.68, 2.18), 5-year overall survival (HR 1.00, 95% CI: 0.99, 1.02), and recurrence-free survival (HR 0.99, 95% CI: 0.96, 1.01) between the two groups.

Conclusion: Among the patients with early-stage cervical cancer, RT is similar to RH in safety and clinical outcomes. Future studies with a randomized design and larger sample sizes are needed to further substantiate these findings.
Case Report: Surgical Reconstruction of a Massive Thoracic Wall Defect After the Resection of an Undifferentiated Radiation-Induced Sarcoma of the Breast
Authors: Rastrelli Marco , Di Prata Claudia , Marconato Roberto , Del Fiore Paolo , Granziera Elisa , Brunello Antonella , Vindigni Vincenzo , Zuin Andrea , Sbaraglia Marta , Tropea Saveria , Mocellin Simone
Published: November 2021

A 54-year-old lady was referred to our institute because of a massive thoracic neoplasm arising from the thoracic wall which infiltrated and dislocated the left breast. Twenty years before, the patient had undergone a quadrantectomy with axillary dissection for an infiltrating ductal carcinoma of the left breast, followed by adjuvant radiotherapy and chemotherapy. A true-cut biopsy of the mass showed a low differentiated malignant neoplasm with spindle-shaped cells. The patient underwent a total-body CT scan which showed a 16 × 15 × 10 cm largely necrotic mass with irregular and undefined margins, with little homolateral round-shaped cervical and mesenteric lymph nodes but no distant metastases. After a multidisciplinary discussion, we proposed surgery as the first therapeutic option. The planned treatment was a wide excision of the mass with the underlying ribs (II-VI) followed by the reconstruction of the thoracic wall using titanium bars covered by the acellular porcine dermis, latissimus dorsi flap, and finally, skin grafts from the thighs.
Psychological Distress and Anxiety Levels Among Health Care Workers at the Height of the COVID-19 Pandemic in the United Arab Emirates
Authors: Saddik Basema , Elbarazi Iffat , Temsah Mohamad-Hani , Saheb Sharif-Askari Fatemeh , Kheder Waad , Hussein Amal , Najim Hellme , Bendardaf Riyad , Hamid Qutayba , Halwani Rabih
Published: November 2021

Objectives: Providing medical care during a global pandemic exposes healthcare workers (HCW) to a high level of risk, causing anxiety and stress. This study aimed to assess the prevalence of anxiety and psychological distress among HCWs during COVID-19.

Methods: We invited HCWs from 3 hospitals across the United Arab Emirates (UAE) to participate in an anonymous online survey between April 19–May 3, 2020. The GAD-7 and K10 measures were used to assess anxiety and psychological distress. Logistic regression models assessed associations between knowledge, attitude, worry, and levels of anxiety and psychological distress.

Results: A total of 481 HCWs participated in this study. The majority of HCWs were female (73.6%) and aged 25–34 years (52.6%). More than half were nurses (55.7%) and had good knowledge of COVID-19 (86.3%). Over a third (37%) of HCWs reported moderate/severe psychological distress in the K10 measure and moderate/severe anxiety (32.3%) in the GAD-7, with frontline workers significantly reporting higher levels of anxiety (36%). Knowledge of COVID-19 did not predict anxiety and psychological distress, however, HCWs who believed COVID-19 was difficult to treat and those who perceived they were at high risk of infection had worse mental health outcomes. Worry about spreading COVID-19 to family, being isolated, contracting COVID-19 and feeling stigmatized had 1.8- to 2.5-fold increased odds of symptoms of mental health problems. Additionally, HCWs who felt the need for psychological support through their workplace showed increased odds of psychological distress.

Conclusion: HCWs in the UAE reported a high prevalence of psychological distress and anxiety while responding to the challenges of COVID-19. The findings from this study emphasize the public, emotional and mental health burden of COVID-19 and highlight the importance for health systems to implement, monitor, and update preventive policies to protect HCWs from contracting the virus while also providing psychological support in the workplace.
Evaluation of the nutritional habits of the population of the Stavropol Territory and risk factors for the development of diseases associated with nutrition
Authors: Vilensky Igor Leonidovich
Published: November 2021

The study and assessment of the nutritional characteristics of the population makes it possible to detect risk factors for metabolic disorders and the development of chronic non-infectious diseases associated with nutrition, which proves the relevance of the study. The purpose of this article is to study the nutritional characteristics of the population of the Stavropol Territory and identify risk factors for the development of diseases associated with nutrition. For this purpose, 3986 people of the Stavropol Territory aged from 31 to 55 were surveyed and questioned, who were divided into two groups: urban population — 1783 people, rural population — 2203 people. The data of anthropometric studies (height, weight, waist and hip circumference) were collected by a generalizing method using an electronic scale (with an accuracy of 0.2 kg), measurement of height — using a stadiometer (with an accuracy of 0.1 cm), followed by calculating the value of the body mass index (BMI). In 300 people (150 urban dwellers and 150 rural dwellers), the total cholesterol content in the blood was studied, which was determined by the enzymatic colorimetric method. The glucose content was determined by the glucose oxidase method. The excretion of iodine in the urine was determined in the morning portion of urine by the cerium-arsenite method with wet ashing of the sediment. Diagnostics of the elemental status of the population was carried out by atomic absorption spectrometry with direct determination of chemical elements. According to the results of the survey, it was found that the risk factors for the development of health disorders in the population of the Stavropol Territory should be considered excessive nutrition in combination with high levels of cholesterol and glucose in the blood, iodine deficiency, decreased levels of calcium, copper, zinc, and low physical activity. More than half of the overweight or obese population had a combination of 3–6 risk factors that worsen their health.
Social and hygienic aspects of risk factors of students‘ learning stress and possible ways of its prevention
Authors: Kulibina Olga Valer'evna , Pleshchev Igor’ Evgen'evich , Skobeleva Tatyana Nikolaevna
Published: November 2021

The article is devoted to the peculiarities of stress resistance among students of the medical University. It is difficult to overestimate the importance of stress hygiene during higher education. Problems with academic performance create discomfort for the student and, of course, increase the overall stress. The purpose of the work is to study the specifics of the influence of certain factors on the overall picture of educational stress in students and their stress resistance. With the help of the methods «Test for learning stress», developed by Yu. V. For the distribution of students into groups depending on the number of academic debts and the "Self-assessment Test of stress resistance" by S. Cohen and G. Willianson, an analysis of the stress resistance of 92 students of the Medical Faculty of the Yaroslavl State Medical University was conducted. As a result of the current study, the main indicators that affect the manifestation of stress in students were identified, such as: workload during study, fear of the future, lack of self — discipline, as well as predictors (prolonged sleep, communication with family, a break in school) that affect its frequency and duration. It is established that the main causes of stress among students are: irregular meals, living away from family, as well as living in a hostel with other students, fear of the future. All this leads to the appearance of behavioral and biological indicators of the severity of stress, which students can reliably determine by depression, fear, anxiety, excitement, difficulty breathing in preparation for the session, as well as headaches and other pains, dry mouth when passing the exam. Based on the study, recommendations have been developed to increase the level of stress tolerance in medical university students.
The influence of wind speed on incidence of the planet population in the context of the COVID-19 pandemic
Authors: Krivosheev Vladimir Vasilievich , Stolyarov Artem Igorevich
Published: November 2021

The pandemic COVID-19 continues to take dozens of human lives and destabilize the economy on the planet. In this regard study of the patterns of external conditions influence on incidence dynamics will stay relevant for a long time. In the article there are results of the study of nature and severity of impact of wind speed on COVID-19 incidence level on different continents. The analysis has made it possible to set that the wind speed has a big impact on COVID-19 incidence among population. This impact is closely related to the contamination level on the territory. With good air quality the increasing of wind speed is generally followed by increasing of the level of incidence due to SARS-CoV-2 long range transport. With satisfying or bad air quality the increasing of wind speed translates into reducing the incidence level due to the contaminants deconcentration. The main SARS-CoV-2 infection vectors are solids. Moreover, the influence of PM 2.5 is particularly harmful for human general health and immune system. Research results lead to a better understanding of physical meaning of wind speed influence on COVID-19 incidence and give an opportunity to predict the periods of the most dangerous infection conditions.
Working conditions and occupational diseases of women in the Republic of Bashkortostan
Authors: Valeeva Elvira Timeryanovna , Shaikhlislamova Elmira Radikovna , Bakirov Akhat Barievich , Gainullina Makhmuza Kalimovna , Akhmetshina Venera Talgatovna , Gabdulvaleeva Elvira Fanisovna
Published: November 2021

The main factors of the working environment that harm a woman’s health in the course of work are considered to be physical exertion and functional overstrain, noise, chemical and biological factors, and microclimate. The most unfavorable sectors of the economy in the Republic of Bashkortostan are manufacturing, construction and the agricultural sector, where the largest number of jobs are registered that do not meet the hygienic standards for the above-mentioned production factors, which undoubtedly serves as the main cause of the development of occupational diseases among women. Material and methods.According to the medical records of the inpatient patient, the acts on the case of occupational disease and the registration form No. 30, the etiological causes and the structure of occupational morbidity by industry sectors of the Republic of Bashkortostan among women for 2016–2020 were studied. Results. Among the subjects of the Russian Federation, the Republic of Bashkortostan for the analyzed fiveyear period ranked 25–27th in terms of employment of women in jobs with harmful and (or) dangerous working conditions, and among the 14 regions of the Volga Federal District — 3–5 places. If in the period 2016–2019 among all the primary established occupational diseases from 32.4 to 43.0 % were women, then by 2020 more than half of all occupational diseases (54.7 %) were detected among women. Of the 114 cases of occupational diseases identified to 85 female workers, a third of them worked in health care (32.9 %), a slightly smaller part (30.6 %) — in mechanical engineering (manufacturing) and a fifth — in the agro-industrial complex (21.1 %). The leading place in the structure of occupational pathology of women was occupied by diseases associated with high physical overload and overstrain of individual organs and systems (54.2 %). The reason for the change in the structure of occupational diseases in the region in 2020 there was a new coronavirus infection-Covid-19 in medical workers, which brought diseases from the influence of a biological factor to the second position. Conclusion. The state of working conditions and occupational morbidity among women workers indicates the lack of an effective mechanism for protecting women’s labor and the need to develop effective legislative documents for the protection of their labor and health.
Docentes de inglés que dejan huellas. Relatos de vida
Authors: Mendieta Toledo Lenin Byron , Mariscal Touzard Laura Iliana , Castillo Noriega Martha Amelia
Published: November 2021

El estudio tuvo como objetivo interpretar el perfil del profesorado universitario de inglés de Ecuador con una mirada sociohistórica a partir de las narrativas y experiencias de los docentes en relación con su formación docente, sistemas de creencias, y valores axiológicos. Este fue un estudio de carácter exploratorio, cualitativo, interpretativo, hermenéutico   y   de   corte   transversal, la población fue escogida a través de la aplicación de encuestas  a  estudiantes  de 6 universidades. Se realizaron relatos de vida para conocer aspectos  importantes  de los sujetos de estudio, los mismos que se bordaron con los relatos de sus colegas y alumnos, todos recolectados  a  través  de entrevistas semiestructuradas y en profundidad. La interpretación de estos resultados demostró que estos profesores son personas humanas con defectos y virtudes, pero, sobre todo, con un sello sublime y pasión por enseñar. Se concluyó que los docentes tienen una sólida formación profesional y su estatus como profesores es el resultado de sus continuas asistencias a seminarios, talleres, maestrías y doctorados.
Clima familiar y rendimiento académico en estudiantes universitarios durante la educación virtual en tiempos de Covid-19
Authors: Sucari León Anibal , Terán Dianderas Amilcar Giovanny , Ticona Arapa Haydee Clady , Chambi Condori Nancy
Published: November 2021

El estudio tuvo como objetivo demostrar la  influencia  del   clima   familiar   en el rendimiento académico de los estudiantes universitarios del I al V ciclo de la Escuela Profesional de Ingeniería de Minas y Educación Inicial de la Universidad Nacional del Altiplano, durante la educación virtual en tiempos de Covid-19. La investigación es de tipo básica con nivel descriptivo y diseño no experimental de corte transversal en el cual se empleó el método científico y estadístico, se trabajó con una muestra de 200 estudiantes, 70 mujeres y 130 varones, con muestreo probabilístico estratificado en una población de 416 estudiantes. Logrando como resultado que si existe una relación  positiva  fuerte y estadísticamente significativa entre el clima familiar y el rendimiento académico con una significancia del 5% en los estudiantes de Ingeniería de Minas y Educación inicial. Concluyendo que es importante tener un buen clima familiar para lograr un rendimiento académico positivo.
Determinan Status Kesehatan Balita di Provinsi Nusa Tenggara Timur Tahun 2019
Authors: Wirawan Muh. Reza Agung , Muchlisoh Siti
Published: November 2021

Kesehatan merupakan hak dasar bagi setiap manusia. Balita merupakan kelompok penduduk yang paling rentan mengalami masalah kesehatan. Provinsi Nusa Tenggara Timur merupakan salah satu provinsi dengan derajat kesehatan balita yang rendah. Dalam kurun waktu 3 tahun, yaitu 2017-2019 persentase penduduk balita atau bayi usia 0-4 tahun yang mempunyai keluhan kesehatan mengalami peningkatan dari 47,69 persen pada tahun 2017 menjadi 52,68 persen pada tahun 2019. Tujuan penelitian ini untuk mengidentifikasi gambaran umum terkait status kesehatan balita, variabel-variabel yang mempengaruhinya serta kecenderungan variabel-variabel tersebut terhadap status kesehatan balita di Nusa Tenggara Timur tahun 2019. Data yang digunakan adalah raw data Survei Sosial Ekonomi Nasional Modul Kesehatan dan Perumahan (Susenas MKP) tahun 2019 yang diperoleh dari Badan Pusat Statistik. Metode analisis yang digunakan adalah regresi logistik biner. Hasil analisis menunjukkan bahwa umur balita, tingkat pengetahuan ibu, status pekerjaan ibu, kesehatan ibu dan akses sanitasi berpengaruh signifikan terhadap status kesehatan balita. Balita dengan karakteristik berusia kurang dari dua tahun yang memiliki ibu berpendidikan minimal tamat SMA, bekerja dan tidak sehat serta memiliki akses sanitasi tidak layak memiliki kecenderungan yang lebih besar untuk tidak sehat
Determinan Status Keterbukaan Diri Mahasiswa Tingkat Akhir
Authors: Wardana Muhammad Rifqi , Budyanra Budyanra
Published: November 2021

Mahasiswa tingkat akhir dituntut untuk menyusun suatu karya tulis dengan mengaplikasikan ilmu yang sudah diperoleh. Pada proses penulisan tugas akhir membutuhkan pembimbingan dari dosen pembimbing, namun pada kondisi pandemi, kegiatan belajar dilakukan secara daring termasuk proses bimbingan, hal ini menjadi sulit bagi beberapa mahasiswa. Kesulitan yang dihadapinya adalah kurangnya keterbukaan (self dislcosure) ke dosen pembimbing yang mana, jika self disclosure mahasiswa tersebut rendah maka akan menghambat penyusunan serta proses bimbingan. Penelitian Zulkifli (2012) menyatakan bahwa 65 persen penyelesaian tugas akhir terhambat karena rendahnya self disclosure, demikian juga dengan mahasiswa Polstat STIS yang sejak pandemi juga mengalami bimbingan secara daring. Penelitian ini bertujuan memberikan gambaran umum status self disclosure dan menganalisis variabel yang memengaruhi status self disclosure mahasiswa tingkat akhir Polstat STIS Tahun Akademik 2020/2021 dengan menggunakan regresi logistik biner. Data penelitian adalah data primer dengan metode samplingnya circular systematic sampling. Berdasarkan gambaran umum diketahui bahwa mahasiswa tingkat akhir memiliki status self dislcosure rendah sebanyak 22,88 persen dan sisanya berstatus tinggi. Dari persamaan regresi logistik didapatkan variabel jenis kelamin mahasiswa (OR = 2,35), status self esteem (OR = 6,34), dan tipe kepribadian (OR = 2,62) dengan tingkat signifikansi lima persen memengaruhi status self disclosure mahasiswa tingkat akhir Polstat STIS Tahun Akademik 2020/2021.
Pemodelan Intervensi Untuk Menganalisis dan Meramalkan Jumlah Penumpang Pesawat di Bandara Soekarno-Hatta Akibat Pandemi Covid-19
Authors: Rianda Fahriza
Published: November 2021

Padatnya aktivitas penerbangan di Bandara Soekarno-Hatta membuat pentingnya menganalisis data jumlah penumpang pesawat serta ramalan dari data tersebut. Data dan ramalan jumlah penumpang pesawat dapat digunakan untuk pengambilan kebijakan bagi pengelola bandara ataupun pemerintah. Namun pandemi Covid-19 yang masuk dan menyebar begitu cepat di Indonesia membuat jumlah penumpang pesawat menurun cukup drastis. Sehingga penelitian ini bertujuan untuk menganalisis dan meramalkan jumlah penumpang pesawat melalui Bandara Soekarno-Hatta akibat pandemi Covid-19. Model yang digunakan pada penelitian ini adalah model intervensi fungsi step. Hasil penelitian menunjukkan pandemi Covid-19 langsung memberikan dampak penurunan yang signifikan pada jumlah penumpang pesawat di Bandara Soekarno-Hatta sebesar 43,48 persen. Penelitian juga menghasilkan ramalan pada data training dan testing dengan persentase kesalahan rata-rata absolut sebesar 7,79 persen dan 14,07 persen. Selain itu, hasil ramalan juga menunjukkan aktivitas penerbangan Bandara Soekarno-Hatta mulai terlihat tanda-tanda pulih pada akhir tahun 2021. Dengan demikian, hasil penelitian ini diharapkan mampu membantu pengelola bandara ataupun pemerintah dalam mengambil kebijakan terkait aktivitas penerbangan di Bandara Soekarno-Hatta selama pandemi Covid-19.
Analisis Variabel yang Memengaruhi Harga Properti Residensial Tipe Kecil di 16 Kota Indonesia Tahun 2015-2019
Authors: Bintang Aisyah , Agustina Neli
Published: November 2021

Hunian merupakan kebutuhan dasar yang harus dipenuhi oleh manusia. Kebijakan pembangunan perumahan pada RPJMN 2015-2019 diarahkan untuk meningkatkan akses masyarakat berpendapatan rendah (MBR) terhadap hunian yang layak. Namun, tingginya harga properti residensial terutama pada kawasan perkotaan menyebabkan MBR tidak dapat mengakses hunian yang layak. Oleh karena itu, penelitian ini akan menganalisis determinan harga properti residensial tipe kecil di 16 kota Indonesia pada tahun 2015-2019. Pemilihan properti residensial tipe kecil bertujuan untuk melihat harga perumahan bagi MBR. Adapun metode analisis yang digunakan adalah analisis regresi data panel dengan SUR. Hasil penelitian menunjukkan bahwa variabel rata-rata upah sebulan buruh konstruksi dan PDRB ADHK menurut pengeluaran memberi pengaruh positif yang signifikan pada perubahan IHPR tipe kecil. Sedangkan variabel share PDRB konstruksi, realisasi FLPP, dan TPT memberi pengaruh negatif yang signifikan pada perubahan IHPR tipe kecil. Melalui penelitian ini, diharapkan pemerintah dapat memberikan kebijakan yang tepat agar kebutuhan properti residensial bagi MBR dapat terpenuhi.
Analisis Pengaruh PDB dan Rasio Keuangan terhadap Harga Saham Perusahaan Big-Cap Sektor Properti yang Terdaftar di BEI pada Masa Pandemi Tahun 2020
Authors: Sijabat Monica Seftaviani , Yuliana Lia
Published: November 2021

Pandemi COVID-19 yang terjadi di Indonesia membawa dampak yang besar bagi pasar modal. Harga saham seluruh sektor mengalami fluktuasi yang signifikan. Sektor properti menjadi sektor yang harga sahamnya paling terpuruk pada tahun 2020. Hal ini terlihat dari pergerakan indeks sektor properti yang mengalami trend cenderung menurun. Pergerakan indeks sektor dipengaruhi oleh pergerakan harga saham perusahaan-perusahaan berkapitalisasi besar (Big-Cap), dimana rata-rata harga saham perusahaan Big-Cap cenderung menurun dibandingkan triwulan IV tahun 2019. Penelitian ini bertujuan untuk mengetahui variabel-variabel apa saja yang memengaruhi harga saham perusahaan Big-Cap sektor properti tahun 2020. Analisis regresi data panel digunakan untuk mengetahui pengaruh PDB, CR, DER, ROE, dan PBV terhadap harga saham perusahaan Big-Cap sektor properti. Hasil penelitian menunjukkan bahwa DER dan ROE berpengaruh negatif, sedangkan PBV berpengaruh secara positif terhadap harga saham perusahaan Big-Cap sektor properti secara signifikan. Variabel CR dan PDB tidak berpengaruh secara signifikan terhadap harga saham perusahaan Big-Cap sektor properti. Oleh sebab itu, investor yang berinvestasi pada saham perusahaan Big-Cap sektor properti perlu mempertimbangkan nilai rasio keuangan, khususnya DER, ROE, dan PBV sebelum mengambil keputusan dalam berinvestasi.
Pengaruh Human Capital Terhadap Durasi Menganggur Pada Pekerja Yang Terkena PHK Akibat Pandemi Covid-19
Authors: Putri Fitriani Aditya
Published: November 2021

Tingkat Pengangguran Terbuka mengalami peningkatan di era pandemi Covid-19. Studi ini bertujuan untuk menganalisis sejauh mana pengaruh human capital (pendidikan dan pelatihan) terhadap durasi menganggur pada pekerja yang terkena PHK akibat pandemi Covid-19 di Indonesia. Studi ini diharapkan dapat memberikan gambaran terkait pentingnya human capital dalam mengurangi pengangguran di Indonesia akibat pandemi Covid-19. Hasil estimasi menggunakan regresi Cox menunjukkan bahwa semakin tinggi tingkat pendidikan pekerja yang terkena PHK akibat pandemi Covid-19 maka semakin lambat keluar dari pengangguran. Sedangkan, pekerja yang pernah terkena PHK akibat pandemi Covid-19 yang pernah mengikuti pelatihan bersertifikat memiliki risiko keluar dari pengangguran yang lebih cepat dibandingkan tidak pernah mengikuti pelatihan bersertifikat. Berdasarkan hasil penelitian dapat disimpulkan bahwa investasi human capital berupa pelatihan dapat mempercepat durasi menganggur pada pekerja yang terkena PHK akibat pandemi Covid-19 di Indonesia, sedangkan semakin tinggi investasi pada pendidikan justru memperlambat durasi menganggur.
Application of Multiplex PCR for the Identification of Oxacillinase Genes and Determination of Antibiotic Resistance Pattern in Environmental Isolates of Acinetobacter baumannii in ICU
Authors: Farajzadeh Anahita , Mirzaee Mohsen , Nanekarani Shahram , Yari Reza
Published: November 2021

Background: Acinetobacter baumannii is a common cause of nosocomial infections. A prominent feature of these bacteria is resistance to carbapenems. This study aimed to identify OXA genes encoding oxacillinase in Acinetobacter baumannii isolates. Methods: This cross-sectional descriptive study was performed on 25 environmental A. baumannii isolates collected from ICU over 8 months. Definitive identification of isolates was performed by biochemical tests and polymerase chain reaction (PCR) of 16s rRNA gene. Antibiotic susceptibility testing was performed on Müller-Hinton agar medium by disk diffusion and E-test. Antibiogram and multiplex PCR data of beta-lactamase genes were collected and analyzed at a significance level of P<0.05 using SPSS 22.0. Results: Except for one isolate, all isolates (96%) were sensitive to polymyxin B and 80% of isolates were sensitive to oxacillin. All isolates were sensitive to meropenem, ampicillin/sulbactam, gentamicin, amikacin, piperacillin, and carbenicillin. The results showed that 25 isolates (100%) had OXA-51 gene, 21 isolates (84%) had OXA-58 gene, one isolate (4%) had OXA-24 gene, and none of the isolates contained OXA-23 gene. Only isolate No.10 had three oxacillinase genes simultaneously and it was resistant to oxacillin, polymyxin B, and cephalothin. Conclusions: The study showed that environmental isolates of ICU do not have pathogenic genes present in the clinical isolates, and how these genes are transferred to the peripheral isolates is an important point that should be studied. Identification of genes encoding carbapenem resistance may help to understand the mechanisms of resistance transfer in A. baumannii. The lack of the OXA-23 gene plays an important role in the susceptibility of isolates to antibiotics and non-emergence of resistant strains.
Transformation of rural settlement and sustainability of rural development in the region
Authors: Tikhii Vladimir , Koreva Olga
Published: November 2021

The current socio-economic situation in rural areas is characterized by a number of problems that hinder sustainable development. The low quality of life, the existing level and quality of life in the village, the lack of social infrastructure, the environmental situation, limited opportunities for work in the village, low incomes of the population compared to the city had a significant impact on the process of migration and deterioration of the quality of the labor force, depopulation of the rural population. In this context, the solution to the problem of rural settlement development is very relevant.

The regional leadership chooses the direction of rural development without taking into account the current socio-economic situation at the municipal level and the peculiarities of rural settlement development, which reduces the effectiveness of territorial administration.

The level of rural development was assessed on the example of the Orel region. The current socio-economic situation in rural areas is characterized by many problems that hinder its transition to sustainable development. The problem of depopulation of the population in rural areas is revealed. At the same time, the destruction of social and engineering infrastructure is observed, the area of cultivated land is reduced, and differences in the level of socio-economic development of the periphery, semi-periphery and suburban areas are increasing. The analysis of the differences in the socio-economic development of the municipalities of the Orel region indicates an increase in intraregional differentiation during the period under review and the absence of an effective intraregional policy aimed at reducing the existing socio-economic asymmetry within the subject of the Federation. Proposals for its solution have been developed, which should be implemented in the context of continuous monitoring of the state and development.
Pelatihan Pelaporan Keuangan Sederhana untuk Wirausaha Usaha Mikro Kecil Menengah (UMKM)
Authors: Istianingsih Sastrodiharjo  , Cahyadi Husadha  , Agus Dharmanto  , Tutiek Yoganingsih  , Milda  Handayani
Published: November 2021

Target dalam kegiatan pengabdian ini dengan tujuan yang ingin dicapai adalah memahami pentingnya perencanaan dan pencatatan keuangan, dengan kesediaannya mengikuti pelatihan ini, tentang pembuatan suatu perencanaan dan pencatatan keuangan yang sederhana, namun cukup baik untuk diterapkan pada kegiatan usaha peserta sampai kepada para peserta pelatihan memahami pembuatan perencanaan dan pencatatan keuangan yang sederhana. Luaran dari kegiatan pengabdian pada masyarakat dalam hal ini adalah pemahaman tentang pengelolaan keuangan kepada para pengusaha disekitar IAI DKI Jakarta agar dapat menjadi pengusaha yang profesinal. Para pengusaha dapat saling berkompetisi sehat dengan mengedepankan kepuasan konsumen. Dengan pengelolaan keuangan yang baik maka mereka akan menjadi wirausahaan yang dapat mengimplementasikan segala ide kreatif dan inovatif sehingga produk yang ditawarkan memberi daya tarik pada konsumennya. Metode pelaksanaan yang digunakan adalah dengan cara ceramah, diskusi dan tutorial soal praktis. Dan untuk evaluasi keberhasilan dari kegiatan ini ditentukan melalui nilai tes akhir yang diperoleh peserta.  Kegiatan penyuluhan dan pelatihan ini dikatakan berhasil bila sebanyak 70 % peserta memperoleh minimal memuaskan.
Pengaruh Kualitas Produk, Kualitas Layanan, Citra Perusahaan, dan Nilai Pelanggan Terhadap Kepuasaan Pelanggan Indihome (Studi Kasus pada PT. Telkom Kota Semarang)
Authors: Syahwi Muhammad , Pantawis Setyo
Published: November 2021

Customer satisfaction is a feeling of pleasure or displeasure with a product or service from a company. This study aims to analyze the effect of product quality, service quality, corporate image, and customer value on customer satisfaction. A total of 100 indihome customers in Semarang City were taken as samples by purposive sampling. The data analysis technique used in this research is multiple linear regression analysis. The results showed that product quality, company image, and customer value had a positive and significant effect. While the service quality variable has no effect on customer satisfaction. The customer value variable has the most dominant influence on indihome customer satisfaction in the city of Semarang.
Demonstration of toroidal metasurfaces through near-field coupling of bright-mode resonators
Authors: Mallick Soumyajyoti , Chourasia Nitin , Singh Rakesh , Roy Chowdhury Dibakar
Published: November 2021

Bright-mode resonances are not well-acknowledged for inducing mode hybridizations. However, we demonstrate that multiple bright resonators coupled through electromagnetic fields can induce resonance mode hybridizations. Although one of the hybridized modes shows parallel magnetic moments, the other demonstrates anti-parallel magnetic moments leading to magnetic toroidal resonances. The excitation of toroidal modes usually demands complex structures and/or bright–dark-mode interactions. However, in this study, we employ only bright resonators to excite toroidal modes. Unlike bright–dark-mode coupling, exclusive bright-mode resonance coupling enables larger free-space energy to merge into the metasystem, which leads to stronger energy confinement in the metasurface array.
MALIGNANT PERIPHERAL NERVE SHEATH TUMOUR AT GASTROESOPHAGEAL JUNCTIONA RARE CASE
Authors: Babu J Praveen , Subramanian Sankar , Sundaram Sandhya , Kumar P Suresh , Asokan Chinni Vikram
Published: November 2021

Malignant peripheral nerve sheath tumors (MPNSTs) are very rare and , represents 3 - 10% of all soft tissue sarcomas.
Approximately half of all such tumors are diagnosed in patients with neurofibromatosis type 1 (NF1). The extremities are
involved most commonly, and the patient's age is usually 20 - 50 years. We herein describe a case of 63 year old lady with
gastroesophageal junction MPNST, which was diagnosed histopathologically after surgery. The patient underwent
curative esophagogastrectomy with D2 lymph node dissection and Roux-en-Y esophagojejunostomy. The
postoperative recovery was uneventful. The ideal adjuvant treatment protocol is yet to be decided due to the relatively
limited number of cases of these tumours previously reported.
Pengaruh Takaran Pupuk Fosfor (P) Terhadap Pertumbuhan Dan Hasil Beberapa Varietas Tanaman Padi (Oryza sativa L.)
Authors: Rosalina Eli , Nirwanto Yogi
Published: November 2021

Padi merupakan tanaman pangan yang menghasilkan makanan pokok penduduk Indonesia. Peningkatan kualitas tanaman sangatlah penting dilakukan, salah satunya melaluiÂ  pemberian Pupuk Posfor (P) dan pemilihan varietas tanaman merespon pemupukan terhadap pertumbuhan. Penelitian bertujuan untuk mengetahui pengaruh pemberian takaran pupuk P terhadap pertumbuhan dan hasil beberapa varietas tanaman padi. Penelitian dilaksanakan di lahan sawah di Desa Telukbuyung, Kecamatan Pakisjaya, kabupaten Karawang. Rancangan yang digunakan dalam penelitian adalah Rancangan Split Plot terdiri dari petak utama varietas terdiri dari empat taraf yaitu: v1 (varietas Ciherang), v2 (varietas Mekongga), v3 (varietas inpari 33), v4 (varietas Cilamaya Muncul). Anak petak takaran pupuk P (biost P) terdiri dari empat taraf yaitu: d0 (tanpa pupuk P), d1 (150 kg ha-1), d2 (300 kg ha-1), d3 (450 kg ha-1). Hasil percobaan menunjukkan terjadi interaksi antara varietas dengan takaran pupuk P terhadap bobot gabah kering panen (GKP) per rumpun. Hasil bobot gabah kering panen (GKP) per rumpun sebesar 572,60 gram diperoleh melalui varietas Mekongga dengan takaran dosis pupuk P 300 kg ha-1.
Consumption Motivations, Savored Positive Emotions, and Savoring Processes in Recalling Travel Experiences of Food
Authors: Sthapit Erose , Björk Peter , Kumaran P. Senthil
Published: November 2021

This study examines the motivation for tasting halal food among non-Muslim tourists during their recent trips away from home. It also integrates the positive psychology concept of savoring by examining the positive emotions savored by non-Muslim tourists on the basis of the broaden-and-build
theory, including the savoring processes used when recalling their recent halal food experiences after returning from holiday. Data were collected from 220 non-Muslim tourists using a self-administered open-ended web-based questionnaire in Amazon MTurk. More than half of the non-Muslim respondents
considered themselves to be food neophiliacs, and the two main motivations for consuming halal food were to experience something new and taste. The most common positive emotions savored by non-Muslim tourists when recalling their recent halal food experiences were joy and love. Taste, togetherness,
and novelty were identified as the dominant factors that intensified respondents' savoring of their halal food experiences and can be linked to three out of four savoring processes: luxuriating, thanksgiving, and marveling.
İnternet ve Sosyal Medya Kullanımı Gebe Kadınları Nasıl Etkiler?
Authors: DEĞİRMENCİLER Büşra , SERCEKUS Pınar , ÖZKAN Sevgi
Published: November 2021

İnternet ve sosyal medya kullanımı dünya çapında olduğu gibi ülkemizde de giderek yaygınlaşmaktadır. Dünya nüfusunun %59.5’i, ülkemizin ise %79’u internet kullanıcısıdır. Ülkemizde internet ve sosyal medya kullanım oranı dünya ortalamasının üzerinde seyretmektedir. Yapılan çalışmalarda sağlık bilgisine ulaşmak için en sık kullanılan kaynağın internet olduğu belirlenmiştir. Kullanıcılar gizlilik, kolay ve hızlı ulaşım gibi nedenlere internet ve sosyal medyadan sağlık bilgisi aramaktadır. Kadınlar erkeklerden daha fazla oranda internetten sağlık bilgisi aramaktadır. Gebelik sürecinde bilgi ihtiyacı artan gebelerin hem interneti hem de sosyal medyayı sıkça kullandıkları çalışmalar ile gösterilmiştir. Gebeler internette doğum süreci, doğum şekilleri, fetal gelişim, yenidoğan bakımı, emzirme, gebelikte meydana gelen fizyolojik değişimler gibi konularda bilgi aramaktadır. Gebeler internet ortamlarından aldıkları bilgileri sağlık profesyonelleri ile paylaşmamaktadır. Bu durum gebelerin internet ve sosyal medyanın sebep olduğu, yanlış, eksik veya fazla bilgi ve mahremiyet kaybı gibi konular açısından risk altında olduğunu ortaya çıkarmaktadır. Yapılan çalışmalar internet ve sosyal medya kullanımı sonucunda gebelerin, doğum korkularının arttığını, doğum deneyimini negatif algıladıklarını ve yanlış kararlar aldığını göstermiştir. Öte yandan internet ve sosyal medya, gebeler tarafından sosyal destek olarak görülmesi nedeniyle olumlu etkilere de sahiptir. İnternet ve sosyal medya kullanımı prenatal bağlanmada olumlu etki gösterebilmektedir. Gebelerin sağlık profesyonelleri tarafından yeterli bilgilendirilmesi ve güvenilir online ortamlara yönlendirilmeleri, yanlış bilgiler edinilmesini engelleyebilir. Aynı zamanda günümüz çağında sağlık profesyonellerinin teknolojik sağlık müdahaleleri oluşturmada da görev alması gerekli olmaktadır. Bu derlemenin amacı gebe kadınların, internet ve sosyal medya kullanımının ve buralardan aldıkları bilgilerden nasıl etkilendiğinin incelenmesidir.
Merging Criteria for Planetesimal Collisions
Authors: Shibata Takashi , Kokubo Eiichiro , Hosono Natsuki
Published: November 2021

In the standard scenario of planet formation, terrestrial planets, ice giants, and cores of gas giants are formed by the accumulation of planetesimals. However, there are few N-body simulation studies of planetesimal accretion that correctly take into account the merging condition of planetesimals. In order to investigate a realistic accretion process of planetesimals, it is necessary to clarify the merging criteria of planetesimals at collision. We perform numerical collision experiments using smoothed particle hydrodynamics and obtain the merging criteria as a function of planetesimal mass and impact parameters for undifferentiated rocky and icy planetesimals and differentiated icy planetesimals. We vary the total mass of colliding planetesimals, their mass ratios, and the impact angle and obtain the critical impact velocity as the merging criteria distinguishing merging from hit-and-run collision. We find that the critical impact velocity normalized by the two-body surface escape velocity decreases with increasing impact angle. The critical impact velocity does not depend on the total mass, while it has a weak positive dependence on the mass ratio. These results barely depend on the composition and internal structure of the planetesimals.
Split Invariant Curves in Rotating Bar Potentials
Authors: Xia Tian-Ye , Shen Juntai
Published: November 2021

Invariant curves are generally closed curves in Poincaré's surface of section. Here we study an interesting dynamical phenomenon, first discovered by Binney et al. in a rotating Kepler potential, where an invariant curve of the surface of section can split into two disconnected line segments under certain conditions, which is distinctively different from the islands of resonant orbits. We first demonstrate the existence of split invariant curves in the Freeman bar model, where all orbits can be described analytically. We find that the split phenomenon occurs when orbits are nearly tangent to the minor/major axis of the bar potential. Moreover, the split phenomenon seems “necessary” to avoid invariant curves intersecting with each other. Such a phenomenon appears only in rotating potentials, and we demonstrate its universal existence in other general rotating bar potentials. It also implies that actions are no longer proportional to the area bounded by an invariant curve if the split occurs, but they can still be computed by other means.
Uncovering Intense Ancient Solar Activity from Naked-eye Observations of Egg-like Sunspots
Authors: Wang Hongrui , Li Huiduan
Published: November 2021

Ancient sunspot records written in classical Chinese provide important information regarding ancient solar activity. The Chinese recorded 14 observations of sunspots that resembled an egg (hereafter, egg record; the word egg is used to represent approximate sunspot sizes) before 1000 CE. However, the egg records in classical Chinese were too short to provide sufficient sunspot details. This study was conducted to decode egg records from 1769 and 1917 through telescopic sunspot observations. The results of our decoding show that egg-like sunspots were generally used by observers in East Asia to represent a very large sunspot group with an approximately elliptical outline. An egg record generally served as a marker of intense solar activity. Three egg records (in 1278, 1769, and 1917) were observed to be close to the solar maxima, with the time difference being smaller than 1 yr. Some egg records could thus be used to identify the solar maxima. The mean time difference between 10 egg records and the nearest solar maxima is 2 yr. Therefore, egg records can provide necessary information for uncovering additional intense solar activity from ancient times.
A Kiloparsec-scale Molecular Wave in the Inner Galaxy: Feather of the Milky Way?
Authors: Veena V. S. , Schilke P. , Sánchez-Monge Á. , Sormani M. C. , Klessen R. S. , Schuller F. , Colombo D. , Csengeri T. , Mattern M. , Urquhart J. S.
Published: November 2021

We report the discovery of a velocity coherent, kiloparsec-scale molecular structure toward the Galactic center region with an angular extent of 30° and an aspect ratio of 60:1. The kinematic distance of the CO structure ranges between 4.4 and 6.5 kpc. Analysis of the velocity data and comparison with the existing spiral arm models support that a major portion of this structure is either a subbranch of the Norma arm or an interarm giant molecular filament, likely to be a kiloparsec-scale feather (or spur) of the Milky Way, similar to those observed in nearby spiral galaxies. The filamentary cloud is at least 2.0 kpc in extent, considering the uncertainties in the kinematic distances, and it could be as long as 4 kpc. The vertical distribution of this highly elongated structure reveals a pattern similar to that of a sinusoidal wave. The exact mechanisms responsible for the origin of such a kiloparsec-scale filament and its wavy morphology remains unclear. The distinct wave-like shape and its peculiar orientation makes this cloud, named as the Gangotri wave, one of the largest and most intriguing structures identified in the Milky Way.
Diagnostic approach to elucidate the efficacy and side effects of direct-acting antivirals in HCV infected patients
Authors: Younas Sonia , Mukhtar Hamid , Gohar Umar Farooq , Alsrhani Abdullah , Alzahrani Badr , Junaid Kashaf , Qamar Muhammad Usman , Ejaz Hasan
Published: November 2021

Introduction: The conventional interferon therapy of hepatitis C virus has been substituted substantially with sofosbuvir and daclatasvir due to constraints in efficacy and tolerability. This study aimed diagnostically to monitor the effectiveness and side effects of direct-acting antivirals in the management of HCV infections.

Methodology: This prospective study was conducted on HCV-infected patients treated with sofosbuvir and daclatasvir. Different serological, biochemical, hematological, and molecular techniques were used for the assessment of patients. Only treatment-naive patients aged ≥ 18 to 75 years received 12 weeks of treatment. The primary endpoint was a sustained virologic response with undetectable HCV RNA in the patients’ serum at the end of the treatment.

Results: We identified 229 cases of confirmed HCV infections by PCR, 94.3% of which had genotype 3. The study population comprised 66% females and 34% males with a median age of 42.2 ± 10.6 SD. Ninety-three percent of the patients accomplished SVR at week 12. The combined therapy of SOF/DAC achieved the highest efficacy rate (92.6%) among the different HCV genotype 3 patients. A statistically significant relationship was observed between low baseline viral load (p < 0.001; 95% CI = 1.2-3.1) and HCV genotype 3 with minor side effects, including lethargy, headache, nausea, insomnia, diarrhea, and fever.

Conclusions: HCV-infected patients can be treated well with an interferon-free SOF/DAC regimen, tolerated with generally mild adverse effects with a higher SVR.
Social inequalities associated with the onset of tuberculosis in disease-prone territories in a city from northeastern Brazil
Authors: De Andrade Hamilton Leandro Pinto , Arroyo Luiz Henrique , Yamamura Melina , Ramos Antônio Carlos Vieira , Crispim Juliane de Almeida , Berra Thaís Zamboni , Neto Marcelino Santos , Pinto Ione Carvalho , Palha Pedro Fredemir , Monroe Aline Aparecida , Alexander Kamila Anise , Arcêncio Ricardo Alexandre
Published: November 2021

Introduction: Tuberculosis remains a major health problem worldwide, killing thousand adults and children every year mainly in developing countries as Brazil. The disease is socially determined, caused mainly by inequalities as overcrowding, bad conditions of housing, unemployment, and limited access to health care. The aim of this study was to identify the social inequalities associated with the onset of tuberculosis in disease-prone territories in a city from the Northeast.

Methodology: This was an ecological study, which has gathered patients diagnosed with tuberculosis through secondary data source in a city from the northeast of Brazil. The GAMLSS statistical model has been applied considering as response variable the count of Tuberculosis cases and the independent variable, the social conditions. The double Poisson distribution was considered in the analysis. The best model fitted was selected according the Akaike information criterion value. For all tests, the p value < 0.05 was considered as statistically significant.

Results: 460 patients with diagnosis of tuberculosis were identified, which represents an incidence of 36.3 cases/100,000 in males and 20.7 cases/100,000 in females. Regarding social inequality associated with tuberculosis, income (households with per capita income between 1/8 and 3 minimum wages), gender and age (Proportion of males under 15 years of age) were associated with the disease. 

Conclusions: The findings evidenced the social determinants associated with tuberculosis, with a greater occurrence of the disease in areas with mostly male children and low-income families, these issues must be managed within and beyond the health sector, which is mandatory for the Tuberculosis elimination.