bluuebunny/crossref_metadata_2025 huggingface dataset:
STRATEGI KOMUNIKASI PEMASARAN CV. HESEAKU TRAVELING YOGYAKARTA DI SAAT PANDEMI COVID-19
Authors: Yudhanto Dwiki , Widiarti Pratiwi Wahyu
Published: April 2024

Abstrak Penelitian ini bertujuan untuk: (1)Mengetahui strategi komunikasi pemasaran yang di terapkan oleh CV. Heseaku Traveling  di Yogyakarta saat pandemi Covid-19, (2)Mengetahui dampak pemasaran CV. Heseaku Traveling Yogyakarta selama masa pandemi covid – 19.Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Subjek dalam penelitian ini yaitu Direktur, wakil direktur, staff bagian pemasaran CV Heseaku Traveling Yogyakarta. Teknik pengumpulan data menggunakan observasi, wawancara, dokumentasi.Teknik pemeriksaan keabsahan data menggunakan triangulasi sumber, teknik, dan waktu yang kemudian di analisis melalui tahapan reduksi data, peyajian data dan verifikasi. Hasil penelitian menunjukkan bahwa: Strategi yang dilakukan dengan mengalihkan promosi pemasarannya dari yang sebelumnya melakukan kunjungan di beberapa  instansi, mengalihkan media promosinya melalui sosial media seperti facebook, Instagram, dan google dan menjelaskan secara detail kepada klien melalui aplikasi Zoom. Dampak pandemi covid-19 pada pemasaran CV Heseaku traveling yakni turun nya omset hingga mencapai. 80% dari masa sebelum pandemi covid-19Kata Kunci : Strategi Komunikasi, Komunikasi Pemasaran, CV Heseaku Traveling, Pandemi Covid-19. Abstract         The aims of the study are : (1) to find out the strategy of marketing communication that is applied by CV Heseaku Traveling in Yogyakarta during the pandemic of covid-19, (2) to know the impact of marketing in CV Heseaku Traveling at Yogyakarta during the covid-19 pandemic.         The study is a descriptive research by using quantitative approach. The subjects of this study are the directur, deputy directur, and marketing staff of CV Heseaku Traveling Yogyakarta. The data collection techniques use observation, interview, and documentation. The inspection techniques of data validity use source triangulation, technique, and time then analyzed by using three steps, that are data reduction, presentation, and verification.        The result of the study shows that : the strategy that is applied by diverting its marketing promotions from previously visiting several agencies, diverting its promotional media through media social such as facebook, instagram, and google, and explain in detail to clients by using Zoom. The affect of covid-19 pandemic on marketing at CV Heseaku Traveling Yogyakarta is the turnover that has decreased to 80% from the period before the pandemic of covid-19.Key Words : Communication strategy, marketing communication, CV Heseaku Traveling, the covid-19 pandemic.
STRATEGI KOMUNIKASI PEMERINTAH DAERAH KABUPATEN BANTUL DALAM PENGELOLAAN INFORMASI BAGI PUBLIK MELALUI PROGRAM ACARA “TAMAN PASEBAN”
Authors: Kusumaningrum Novia Agri , Widiarti Pratiwi Wahyu
Published: April 2024

AbstrakTujuan dari penelitian ini untuk mengetahui strategi komunikasi yang dilakukan oleh Diskominfo Bantul dalam mewujudkan implementasi kebijakan keterbukaan informasi bagi publik melalui acara “Taman Paseban” dan mengetahui sosialisasi acara “Taman Paseban” melalui media komunikasi yang dikelola oleh Diskominfo Bantul dalam upaya publikasi program acara kepada masyarakat. Penelitian ini merupakan penelitian kualitatif deskriptif dengan pengambilan data berupa wawancara dan studi dokumen. Hasil penelitian ini menunjukkan bahwa: (1). Penerapan model Hafied Cangara mengenai strategi komunikasi yang dapat berjalan dengan baik berdasarkan bentuk dari kerjasama antara Diskominfo Bantul dengan instansi terkait, yaitu CV. Pita Biru advertising dan TVRI stasiun televisi Daerah Istimewa Yogyakarta adalah suatu program acara berbentuk talk show yang bermaterikan tema mengenai berbagai program kebijakan pemerintah. (2). Penggunaan media komunikasi publik, yaitu sosial media yang dikelola oleh Diskominfo Bantul dengan mengunggah poster gambar dan ditambahkan keterangan tulisan sebagai informasi acara untuk dibagikan kepada masyarakat agar menonton siaran program “Taman Paseban”.Kata kunci: Strategi Komunikasi, Informasi Publik, Acara “Taman Paseban”AbstractThe goal of this research is to determine the communication strategy used by the Bantul Regency Communication and Information Office (Diskominfo kabupaten Bantul) in implementing public information disclosure policies through the "Taman Paseban" event and knowing about the socialization of the "Taman Paseban" event through communication media administered by the Diskominfo kabupaten Bantul in order to publicize the event program to the Bantul regency community. This is a descriptive qualitative study with primary data collected through semi-structured interviews and secondary data collected through document studies. The findings of this study show that: (1) The Hafied Cangara model may be applied to a communication strategy that works well when it is based on a type of cooperation between the Diskominfo Kabupaten Bantul and the necessary agencies, especially CV Pita Biru advertising and TVRI, the Yogyakarta Special Region television station, present a chat show with a focus on various government policy programs. (2). The use of public communication platforms, including as social media administered by Diskominfo kabupaten Bantul, to share event information with the public by uploading picture posters and adding written descriptions as event information to watch the "Taman Paseban" program broadcast. Keywords: Communication Strategy, Information for the Public, “Taman Paseban” Event.
UNGGAHAN INFO CEGATAN JOGJA (ICJ) SEBAGAI SUMBER INFORMASI BAGI MASYARAKAT YOGYAKARTA UNGGAHAN INFO CEGATAN JOGJA (ICJ) SEBAGAI SUMBER INFORMASI BAGI MASYARAKAT YOGYAKARTA
Authors: Hartama Amrullah Surya , Suranto Suranto
Published: April 2024

AbstrakPenelitian ini bertujuan untuk mengetahui bagaimana unggahan Info Cegatan Jogja (ICJ) sebagai sumber informasi bagi masyarkat Yogyakarta. Penelitian ini merupakan penelitian analisis konten yang menggunakan pendekatan kualitatif. Penelitian ini dilaksanakan pada 11 Januari hingga 8 Februari  2021 di Grup Info Cegatan Joga (ICJ) pada media digital facebook. Hasil penelitian menunjukkan bahwa (1) terdapat enam jenis-jenis informasi dalam grup Info Cegatan Jogja yaitu iklan, berita kehilangan, keluhan, informasi kecelakaan, informasi tindakan kriminal dan informasi bencana alam, (2) Unggahan Grup Info Cegatan Jogja (ICJ) sudah memenuhi karakteristik informasi yang berkualitas karena sudah meliputi karakteristik effectiveness, efficiency, confidentialit, integrity, availability, dan reliability.  Tetapi masih belum memenuhi salah satu karakteristik informasi berkualitas compliance, (3) Grup Info Cegatan Jogja (ICJ) memiliki manfaat yang banyak bagi masyarakat Yogyakarta. Kata kunci : Unggahan, Informasi, Info Cegatan Jogja(ICJ) AbstractThis  study aims to find out about the upload on Info Cegatan Jogja (ICJ)  as a source of information for the people of Yogyakarta. This research is a content analysis research that uses a qualitative approach. This research was conducted from 11 January 2021 to 8 February 2021 at the Info Group Cegatan Jogja (ICJ) on the digital media facebook. The results showed that (1) there were six types of information in the Info CegatanJogja group, namely advertisements, news of loss, complaints, accident information, information on criminal acts and information on natural disasters. Based on the percentage diagram for each upload, posts are dominated by advertisements, followed by information loss and the least percentage is entertainment uploads (2) Uploads of the JogjaCegatan Info Group (ICJ) have met the characteristics of quality information because they include the characteristics of effectiveness, efficiency, confidentiality, integrity, availability, and reliability. However, it still does not meet one of the characteristics of compliance quality information because the uploaded information is not a criterion for information about business. (3) The JogjaCegatan Info Group (ICJ) is very useful for the people of Yogyakarta. This is evidenced by the observations of researchers who found many positive responses from the people of Yogyakarta.Keywords : Upload, Information, Jogja Intercept Info (ICJ)
Gatekeeping konten viral media sosial (studi kasus harianjogja.com, jogja.tribunnews.com, & suarajogja.id)
Authors: Setiawan Hery , Handayani Wuri
Published: April 2024

AbstrakPenelitian ini berusaha menjawab bagaimana aktivitas serta faktor pengaruh dari gatekeeping yang dilakukan media massa terhadap konten viral di media sosial. Metodologi studi kasus digunakan untuk menelusuri sistem kerja dan metode redaksi yang diterapkan oleh tiga media massa dari Yogyakarta. Data penelitian diperoleh melalui wawancara terhadap redaktur, asisten redaktur, uploader, dan reporter; serta dokumentasi pemberitaan. Peneliti menggunakan Teori Hierarki Pengaruh (Shoemaker Reese, 2014) untuk membahas aktivitas gatekeeping media massa di era internet serta faktor-faktor yang memengaruhinya. Hasil penelitian menunjukkan bahwa media massa masih memiliki peran dalam melakukan seleksi terhadap konten viral media sosial. Namun, peran tersebut tidak dilakukan secara ketat karena nyaris semua konten viral terpilih lolos begitu saja melewati gerbang keredaksian. Konten viral hanya dinilai secara berbeda berdasarkan sensitivitas informasi. Gatekeeping konten viral dipengaruhi oleh level institusi sosial (pasar pembaca dan perubahan teknologi media). Media sosial Twitter menjadi platform news-breaker tool andalan awak media karena unggul dari segi kecepatan dan kebaruan informasi.Kata kunci: gatekeeping, konten viral, media massa, teori hierarki pengaruh AbstractThis research was conducted to gain an understanding of the activity and influence factor of mass media gatekeeping toward social media viral content. Three Yogyakarta-based local online media were explored by the case study method. Research data was collected through interviews with the editor, assistant editor, uploader, and reporter; and news stories documentation. The hierarchy of influence theory (Shoemaker Reese, 2014) was applied as the main tool to analyze entire data. The result shows that mass media resist their role as a gatekeeper by selecting and fact-checking information. However, they do not carry out strictly as almost selected viral contents are able to pass the editorial gate without any reduction or rejection. Viral contents are considered based on their sensitivity. The gatekeeping of social media viral content is mainly influenced by the institutional level (market reader and technological shifting). Twitter is the favorite news-breaking tool for the rapidness of information updates.Keywords: gatekeeping, viral content, mass media, the theory of influence hierarchy
Efektivitas meme pada akun Twitter masa kebijakan WFH (komparasi engagement tipe post akun @memefess)
Authors: Kusumawardani Anton , Setiawan Benni
Published: April 2024

Penelitian ini bertujuan untuk mengetahui perbandingan tingkat engagement ditinjau dari reply, retweet, dan likes pada tipe post Twitter. Sebagai penelitian kuantitatif dengan menggunakan metode pengujian hipotesis ex post facto, penelitian ini memiliki 3021 sumber data post. Penetapan sumber data mengacu pada kebijakan Work From Home (WFH) 16 Maret - 29 Mei 2020, melalui pernyataan resmi Dwi Wahyu Atmaji selaku Sekretaris Kementerian PANRB yang telah dipertimbangkan terhadap Keppres Nomor 11 dan 12 Tahun 2020. Hasil dari penelitian menunjukkan bahwa: 1) Terdapat perbedaan yang signifikan antara tipe post pada foto dan video ditinjau dari reply dengan nilai signifikasi 0,013; retweet 0,000; likes 0,003. 2) Tingkat engagement tipe post foto lebih besar daripada video ditinjau dari reply, retweet, likes. 3) Terdapat perbedaan yang siginifikan antara tipe post foto dan GIF ditinjau dari reply dengan nilai signifikasi 0,013; retweet 0,000; likes 0,003. 4) Tingkat engagement tipe post foto lebih besar dari GIF ditinjau dari reply, retweet, likes. 5) Tidak ada perbedaan antara tipe post video dan GIF ditinjau dari reply dengan nilai signifikasi 1,000; retweet 1,000; likes 1,000. 6) Tipe post video dan GIF memiliki tingkat engagement yang sama baik ditinjau dari reply, retweet, likes. This study aims to determine the comparison level of engagement in terms of replies, retweets, and likes on types of Twitter posts. As quantitative research on using ex post facto method of hypothesis testing, this study has 3021 data sources post. The determination of the data source refers to the policy of Work From Home (WFH) March 16 - May 29 2020, through an official statement by Dwi Wahyu Atmaji as Secretary of the Ministry of PANRB which has been considered against Presidential Decrees No. 11 and 12 of 2020. The results showed that: 1) There was a significant difference between types of posts in the photo and videos in terms of replies with a significance value of 0,013; retweets 0,000; likes 0,003. 2) The level of engagement of types post photo is greater than videos in terms of replies, retweets, and likes. 3) There was a significant difference between types of posts in the photo and GIF in terms of replies with a significance value of 0,013; retweets 0,000; likes 0,003. 4) The level of engagement of types post photo is greater than GIF in terms of replies, retweets, and likes. 5) There is no difference between types of post in the videos and GIF in terms of replies with a significance value of 1,000; retweets 1,000; likes 1,000. 6) Types post videos and GIF have the level of engagement same in terms of replies, retweets, likes.
Efficacy of differentiated targeted interferon and immunomodulatory therapy focused on pathological immunophenotypes in patients with atypical chronic active herpesvirus infections
Authors: Nesterova I. V. , Khalturina E. O.
Published: April 2024

Objective: In a prospective cohort study to evaluate the clinical and immunological efficacy of differentiated targeted interferon and immunomodulatory therapies focused on identified pathological immunophenotropes and associated clinical manifestations in immunocompromised patients suffering from atypical chronic active herpes viral infections (ACA-HVI).

Materials and methods: 335 patients suffering from mixed-AHA-HVI were examined. The study complex included: methods for detecting herpesviruses: serodiagnosis, PCR-RV; immunological methods: a research of subpopulation of blood lymphocytes (method of a flow cytometry), determination of the spontaneous and induced products of IFNα and IFNγ, levels of serum cytokines and immunoglobulins (IL-1β, IL-6, IL-17, TNFα and IFNα and IFNγ, Ig A, M, G) by ELISA. The study was approved by the ethics board and informed consent was obtained from all patients.

Results: Integral formulas of disorders in the antiviral immune defense system were created, which made it possible to isolate 3 pathological immunophenotypes (PIF): PIF1: NG↓+ind.IFNα/IFNγ↓+CTL↓+EKK↓+IgM↑+hypecytokinemiya (IL-1β↑+IL-6↑+TNFα↑); PIF2: NG↓+ ind. IFNα/IFNγ↓ + EKK↓+ IgG↓+hypercytokinemiya (IL-1β↑+IL-6↑+TNFα↑) and PIF3: NG↓+ind.IFNα/IFNγ↓+hypercytokinemiya (IL-1β↑+IL- 6↑+TNFα↑). Taking into account the identified disorders, a program of targeted interferon and immunomodulatory therapy was developed for each PIF: local and systemic IFN therapy + hexapeptide was developed for PIF1; for PIF2- local and systemic IFN therapy + glucosaminimuramyldipeptide; for PIF3-local and systemic IFN therapy.

Conclusions: High clinical efficacy was demonstrated in 100% of patients with three groups of ACA-HVI. Immunological effectiveness of targeted interferon and immunomodulatory therapy programs: 89.5% for PIF1; for PIF2-57.6% and for PIF3- 37.5% of cases.
The current situation of echinococcosis in the Far East and South of Russia
Authors: Dragomeretskaya A. G. , Trotsenko O. E. , Logvin F. V. , Tverdokhlebova T. I. , Romanova E. B. , Ishchenkova I. V. , Moskvina Yu. I. , Dimidova L. L. , Chernikova M. P.
Published: April 2024

Objective:to assess the epidemic situation of echinococcosis in the period 2012–2022 in the endemic territories of the Far Eastern Federal District and South of Russia.

Materials and methods:based on the data of the annual statistical reporting forms No. 2 "Information on infectious and parasitic diseases", data from the Reference Center for Monitoring Larval Helminthiasis of Rostov Research Institute Microbiology and Parasitology of Rospotrebnadzor, an analysis of the incidence of echinococcosis in the territories of the Far East and South of Russia in the period 2012–2022 was carried out. For seroepidemiological examination of a conditionally healthy population by the ELISA method, the diagnostic kit "Echinococcus-IgG-ELISA-BEST" (JSC "Vector-Best", Novosibirsk) was used.

Results:it is shown that the epidemiological situation of echinococcosis is characterized by pronounced territorial unevenness. In the south of Russia, epidemiological problems with echinococcosis persisted in Kalmykia (0.74–2.19 cases per 100,000 population) and in the Astrakhan region (0.60–1.48 cases per 100,000 population). Among the relatively healthy population, the average seropositivity to E.granulosus antigens in the Far East was 5.8%, in the south of Russia — 2,6%. Conclusions: the data obtained indicate an unfavorable epidemiological situation for echinococcosis in a number of regions of the Far East and South of Russia.
Episootological features of tularemia in the Donetsk region
Authors: Skripka L. V.
Published: April 2024

Objective: to evaluate epizootic monitoring of tularemia in the Donetsk region.

Materials and methods: methods of retrospective, statistical, and comparative analysis were used. The sources of infection were investigated using serological and biological methods. The data of industry statistical reporting on form No. 40-annual of the department of especially dangerous infections of the Donetsk regional Sanitary and Epidemiological Station (since 2013 — SSESU, since 2015 — Republican Center for Sanitary and Epidemiological Surveillance of the State Sanitary and Epidemiological Service of the Ministry of Health of the DPR) were used. 20 "Maps of epizootological and epidemiological examination of the focus of zoonotic disease" (F.391/y) were studied.

Results: since 1987, the number of enzootic territories in the Donetsk region has increased annually: from 2 settlements in 1987 to 79 (in 4 cities and 16 districts) in 2023. With the beginning of active hostilities, the epidemic process of tularemia in Donbass has sharply intensified. Antibody titers (1:80 and 1:160) for tularemia were detected in environmental samples: in the North Steppe zone — 6.2%, Donetsk-Kryazhnaya — 10.4%, Primorsko-steppe — 15.8%. In the study of mouse-like rodents, 6 cultures of Francisella tularensis holarctica biovar II era R were isolated, resistance of the strain to ampicillin, cefotaxime, erythromycin, clindamycin, polymyxin was established; sensitivity to gentamicin, fluoroquinolones, rifampicin, doxycycline, levomycetin.

Conclusions: the activation of epizootic processes of tularemia in the DPR is associated with the conduct of hostilities. High titers of antibodies to tularemia in environmental samples are noted in the south of the Donetsk region.
“White spots” in the diagnostic search for the causes of recurrent miscarriage
Authors: Lebedenko E. Yu. , Mikhelson Ar. A. , Mikhelson A. A. , Zmienko V. A. , Sagamonov A. S. , Kormanukov H. Yu.
Published: April 2024

Recurrent pregnancy loss is not only a medical, but also a social problem of a multifactorial nature. This problem remains unsolvable despite the constant search and application of new diagnostic and therapeutic strategies. The presented review examines the literature data on evidence-based methods for diagnosing the causes of miscarriage, as well as methods whose use remains controversial. Special attention is paid to the immunological foundations of a normal pregnancy formation, the violation of which creates the prerequisites for a recurrent miscarriage. The paper also analyzes current data on the role of endometrial receptivity and the contribution of the male factor to the problem of miscarriage, and presents prospects for further research on the problem of recurrent pregnancy loss.
El efecto heterogéneo de las remuneraciones laborales en la inflación mexicana
Authors: Hernández Ramírez Eric , Sánchez Vargas Armando , López Herrera Francisco
Published: April 2024

En este artículo analizamos el impacto heterogéneo de un incremento de los costos de las remuneraciones a los trabajadores sobre el nivel de precios general y sectorial de la economía mexicana. Mediante un modelo de precios de insumo producto con funciones de costos flexibles, simulamos escenarios considerando un aumento de 10% en las remuneraciones a los trabajadores. Encontramos que el aumento de precios a nivel de sectores económicos es heterogéneo y depende tanto de su estructura de costos como de cuán flexibles sean dichos sectores para sustituir. A nivel global, para costos fijos un aumento del 10% tiene un efecto sobre la inflación de 2.2%, mientras para costos flexibles de 1.98%. La originalidad de este trabajo consiste en el hallazgo de impactos heterogéneos, dando pie a la propuesta de políticas públicas focalizadas por sector. Naturalmente, el modelo está limitado por los propios supuestos del modelo de insumo producto.
Composición química y evaluación del sinergismo de la actividad antioxidante de mezclas de los aceites esenciales de Luma chequen (Arrayan) y Citrus maxima (Pomelo).
Authors: Jiménez Carla del Carpio- , Gutierrez-Chavez R. Giancarlo , Quispe-Dávila H. Angelica , TomayllaCruz Ciro , Urrunaga-Ormachea Mario J.
Published: April 2024

Los aceites esenciales son componentes bioactivos usados en áreas como la medicina, la farmacia, la cosmética y la industria alimentaria, se emplean como conservantes por sus propiedades antioxidantes. El objetivo
de la presente investigación fue extraer, determinar las propiedades fisicoquímicas y cuantificar por cromatografía de gases/espectrometría de masas los principales componentes de los aceites esenciales de Luma chequen y Citrus maxima, así como evaluar la actividad antioxidante de la mezcla de ambos aceites usando el
método de inhibición del radical ácido 2,2'-azino-bis-3-etilbenzotiazolina-6-sulfónico (ABTS•+). El rendimiento de extracción fue de 0,82% y de 0,95% para Luma chequen y Citrus maxima respectivamente. El pH
fue de 4,5 y 5,5; la densidad fue de 0,877 g/ml y 0,844 g/ml y el índice de refracción fue de 1,4688 y 1,4741
respectivamente. Ambos aceites esenciales presentan alto contenido de monoterpenos siendo el α-pineno
(57,6%) el más abundante para Luma chequen y el limoneno (30,3%) para Citrus maxima. Respecto a la
actividad antioxidante; la inhibición del radical ABTS•+ fue de 49,1% y 93,4% respectivamente, sin embargo,
la mezcla constituida por 50% de aceite esencial de Luma chequen y 50% de aceite esencial de Citrus maxima
presentó un porcentaje de inhibición de 102.8%, evidenciándose sinergismo.
Keywords: Luma chequen, Citrus maxima, antioxidante, monoterpenos, sinergismo
Raw, Unadulterated African Honey for Ulcer Healing in Leprosy: Protocol for the Honey Experiment on Leprosy Ulcer (HELP) Randomized Controlled Trial
Authors: Udo Sunday , Ogbu Sunday Pius , Tsaku Paul Alumbugu , Oladejo Israel Olaoluwa , Meka Anthony , Ugwu Linda Chinonso , Ajisola Motunrayo , Akinyemi Joshua , Oladejo Abiola , Omigbodun Akinyinka , Choudhury Sopna Mannan , Sartori Jo , Ilozumba Onaedo , Watson Sam , Lilford Richard
Published: April 2024

Background

Leprosy leads to nerve damage and slow-healing ulcers, which are treatable with routine therapy. There has been a recent resurgence of interest in the use of honey for the treatment of different kinds of wounds.

Objective

The aim of this study, Honey Experiment on Leprosy Ulcer (HELP), is to evaluate the healing properties of raw, unadulterated African honey in comparison with normal saline dressing for the treatment leprosy ulcers.

Methods

This is a multicenter, comparative, prospective, single-blinded, parallel-group, and 1:1 individually randomized controlled trial to be conducted at The Leprosy Referral Hospital, Chanchaga in Minna, Niger State, North Central Nigeria, and St. Benedict Tuberculosis and Leprosy Rehabilitation Hospital in Ogoja, Cross River State, South-South Nigeria. Raw, unadulterated honey will be used in the ulcer dressing of eligible, consenting participants in the intervention group, whereas those in the control group will be treated by dressing with normal saline. The main outcomes will be the proportion of complete healing and the rate of healing up to 84 days after randomization. Follow-up will be conducted 6 months after randomization. We aim to enroll 90‐130 participants into the study. Blinded observers will examine photographs of ulcers to determine the outcomes.

Results

The recruitment of trial participants began on March 14, 2022, and has been continuing for approximately 24 months.

Conclusions

Our study will provide an unbiased estimate of the effect of honey on the healing of neuropathic ulcers.
Adoption of Augmented Reality in Educational Programs for Nurses in Intensive Care Units of Tertiary Academic Hospitals: Mixed Methods Study
Authors: Yoo Suyoung , Heo Sejin , Song Soojin , Park Aeyoung , Cho Hyunchung , Kim Yuna , Cha Won Chul , Kim Kyeongsug , Son Meong Hi
Published: April 2024

Background

In the wake of challenges brought by the COVID-19 pandemic to conventional medical education, the demand for innovative teaching methods has surged. Nurse training, with its focus on hands-on practice and self-directed learning, encountered significant hurdles with conventional approaches. Augmented reality (AR) offers a potential solution to addressing this issue.

Objective

The aim of this study was to develop, introduce, and evaluate an AR-based educational program designed for nurses, focusing on its potential to facilitate hands-on practice and self-directed learning.

Methods

An AR-based educational program for nursing was developed anchored by the Kern six-step framework. First, we identified challenges in conventional teaching methods through interviews and literature reviews. Interviews highlighted the need for hands-on practice and on-site self-directed learning with feedback from a remote site. The training goals of the platform were established by expert trainers and researchers, focusing on the utilization of a ventilator and extracorporeal membrane oxygenation system. Intensive care nurses were enrolled to evaluate AR education. We then assessed usability and acceptability of the AR training using the System Usability Scale and Technology Acceptance Model with intensive care nurses who agreed to test the new platform. Additionally, selected participants provided deeper insights through semistructured interviews.

Results

This study highlights feasibility and key considerations for implementing an AR-based educational program for intensive care unit nurses, focusing on training objectives of the platform. Implemented over 2 months using Microsoft Dynamics 365 Guides and HoloLens 2, 28 participants were trained. Feedback gathered through interviews with the trainers and trainees indicated a positive reception. In particular, the trainees mentioned finding AR particularly useful for hands-on learning, appreciating its realism and the ability for repetitive practice. However, some challenges such as difficulty in adapting to the new technology were expressed. Overall, AR exhibits potential as a supplementary tool in nurse education.

Conclusions

To our knowledge, this is the first study to substitute conventional methods with AR in this specific area of critical care nursing. These results indicate the multiple principal factors to take into consideration when adopting AR education in hospitals. AR is effective in promoting self-directed learning and hands-on practice, with participants displaying active engagement and enhanced skill acquisition.

Trial Registration

ClinicalTrials.gov NCT05629663; https://clinicaltrials.gov/study/NCT05629663.
Response of Unvaccinated US Adults to Official Information About the Pause in Use of the Johnson & Johnson–Janssen COVID-19 Vaccine: Cross-Sectional Survey Study (Preprint)
Authors: Mishra Vishala , Dexter Joseph P
Published: April 2024

UNSTRUCTURED

Using a rapid response web-based survey, we identified gaps in public understanding of the Centers for Disease Control and Prevention’s messaging about the pause in use of the Johnson & Johnson–Janssen COVID-19 vaccine and estimated changes in vaccine hesitancy using counterfactual questions.
Impact of Consumer Wearables Data on Pediatric Surgery Clinicians’ Management: Multi-Institutional Scenario-Based Usability Study (Preprint)
Authors: Carter Michela , Linton Samuel C , Zeineddin Suhail , Pitt J Benjamin , De Boer Christopher , Figueroa Angie , Gosain Ankush , Lanning David , Lesher Aaron , Islam Saleem , Sathya Chethan , Holl Jane L , Ghomrawi Hassan MK , Abdullah Fizan
Published: April 2024

BACKGROUND

At present, parents lack objective methods to evaluate their child’s postoperative recovery following discharge from the hospital. As a result, clinicians are dependent upon a parent’s subjective assessment of the child’s health status and the child’s ability to communicate their symptoms. This subjective nature of home monitoring contributes to unnecessary emergency department (ED) use as well as delays in treatment. However, the integration of data remotely collected using a consumer wearable device has the potential to provide clinicians with objective metrics for postoperative patients to facilitate informed longitudinal, remote assessment.

OBJECTIVE

This multi-institutional study aimed to evaluate the impact of adding actual and simulated objective recovery data that were collected remotely using a consumer wearable device to simulated postoperative telephone encounters on clinicians’ management.

METHODS

In total, 3 simulated telephone scenarios of patients after an appendectomy were presented to clinicians at 5 children’s hospitals. Each scenario was then supplemented with wearable data concerning or reassuring against a postoperative complication. Clinicians rated their likelihood of ED referral before and after the addition of wearable data to evaluate if it changed their recommendation. Clinicians reported confidence in their decision-making.

RESULTS

In total, 34 clinicians participated. Compared with the scenario alone, the addition of reassuring wearable data resulted in a decreased likelihood of ED referral for all 3 scenarios (P<.01). When presented with concerning wearable data, there was an increased likelihood of ED referral for 1 of 3 scenarios (P=.72, P=.17, and P<.001). At the institutional level, there was no difference between the 5 institutions in how the wearable data changed the likelihood of ED referral for all 3 scenarios. With the addition of wearable data, 76% (19/25) to 88% (21/24 and 22/25) of clinicians reported increased confidence in their recommendations.

CONCLUSIONS

The addition of wearable data to simulated telephone scenarios for postdischarge patients who underwent pediatric surgery impacted clinicians’ remote patient management at 5 pediatric institutions and increased clinician confidence. Wearable devices are capable of providing real-time measures of recovery, which can be used as a postoperative monitoring tool to reduce delays in care and avoidable health care use.
Families’ Experiences With Family-Focused Web-Based Interventions for Improving Health: Qualitative Systematic Literature Review (Preprint)
Authors: Zhu Diana , Dordevic Aimee L , Davidson Zoe E , Gibson Simone
Published: April 2024

BACKGROUND

eHealth interventions can favorably impact health outcomes and encourage health-promoting behaviors in children. More insight is needed from the perspective of children and their families regarding eHealth interventions, including features influencing program effectiveness.

OBJECTIVE

This review aimed to explore families’ experiences with family-focused web-based interventions for improving health.

METHODS

Five databases were searched on October 26, 2022—updated on October 24, 2023—for studies reporting qualitative data on participating children or their caregivers’ experiences with web-based programs. Study identification was performed in duplicate and studies were independently appraised for quality. Thematic synthesis was undertaken on qualitative data extracted from the results section of each included article.

RESULTS

Of 5524 articles identified, 28 articles were included. The studies examined the experiences of school-aged children (aged 5-18 years) and their caregivers (mostly mothers) with 26 web-based interventions that were developed to manage 17 different health conditions or influence health-supporting behaviors. Six themes were identified on families’ experiences: connecting with others, agency of learning, program reputability or credibility, program flexibility, meeting participants’ needs regarding program content or delivery, and impact on lifestyle.

CONCLUSIONS

Families positively perceived family-focused web-based interventions, finding value in quality connections and experiencing social support; intervention features aligned with behavioral and self-management principles. Key considerations were highlighted for program developers and health care professionals on ways to adapt eHealth elements to meet families’ health-related needs. Continued research examining families’ experiences with eHealth interventions is needed, including the experiences of families from diverse populations and distinguishing the perspectives of children, their caregivers, and other family members, to inform the expansion of family-focused eHealth interventions in health care systems.

CLINICALTRIAL

PROSPERO CRD42022363874; https://tinyurl.com/3xxa8enz
Distinguishing Patient Interests between Non-therapeutic vs. Therapeutic Use of Methylphenidate as a Study Aid: A Topic Modelling of Attention-Deficit/Hyperactivity Disorder Social Media Community (Preprint)
Authors: Kim Maryanne , Shin Seungyeon , Hong Song Hee
Published: April 2024

BACKGROUND

Methylphenidate (MPH) is commonly used off-label as a study aid, raising concerns about its non-therapeutic use and associated risks. While use of MPH as a study aid is discouraged, students with academic difficulties would therapeutically need MPH for enhancing their executive function. Understanding user topic patterns related to therapeutic and non-therapeutic use of MPH can provide insights into factors influencing usage patterns and guide interventions.

OBJECTIVE

This study aimed to investigate user topic patterns associated with therapeutic and non-therapeutic use of MPH as study aids, utilizing social media posts.

METHODS

We utilized Latent Dirichlet Allocation (LDA) topic modeling to identify underlying themes from user-generated posts on an Attention-Deficit/Hyperactivity Disorder (ADHD) social media platform. The posts pertaining to MPH use for academic purposes (N=1,447) were classified into therapeutic and non-therapeutic use and the distribution of posting season and topic prevalence were assessed between two usage patterns. Logistic regression and interaction analyses were conducted to examine associations between topics and MPH usage, accounting for seasonal variations.

RESULTS

The result of LDA topic modeling revealed six key topics: effect alteration, atomoxetine therapy, ADHD challenges, diagnosis and consultation, brain stimulation, and academic performance. While effect alteration (OR=6.31, P=.017) and brain stimulation (OR=6.63, P=.042), were significantly associated with non-therapeutic use, atomoxetine therapy (OR=0.04, P<.001) and ADHD challenges (OR=0.16, P=.013) were linked to therapeutic use. Interaction analyses revealed synergistic and antagonistic effects between topic pairs, modulating their impacts on usage patterns. Pro-therapeutic topics such as atomoxetine therapy and ADHD challenges exhibited a shift towards non-therapeutic use during non-winter seasons.

CONCLUSIONS

Our findings provide insights into the complex interplay of user topics associated with therapeutic and non-therapeutic use of MPH for academic purposes. Understanding these patterns can inform targeted interventions aimed at promoting safe and appropriate MPH use among students, particularly during seasons when misuse risks may increase among those experiencing ADHD challenges.
Book Review: Women, Peace, and Security: Feminist Perspectives on International Affairs by Caroline Leprince & Cassandra Steer (editor)
Authors: Viartasiwi Nino , Ramadhani Geubrina Putri
Published: April 2024

None
Global South Responses to China’s BRI Projects: A Case Study of Jakarta-Bandung High-Speed Railway Project
Authors: Prasetyo Kanyadibya Cendana
Published: April 2024

China's rise as a global power in the 21st century, marked by its economic growth and political influence, has been exemplified through initiatives like the Belt and Road Initiative (BRI). The BRI has extended China's geoeconomic and geopolitical influence across Asia, Africa, Latin America, and Europe. While existing literature predominantly focuses on China's actions, this study shifts the spotlight to Global South nations' responses and strategic policies, particularly Indonesia, in the context of China's BRI projects. Drawing upon in-depth interviews, literature review, and social media analysis, this research examines how Indonesia has actively shaped the Jakarta-Bandung High-Speed Railway project within the BRI framework to pursue its objectives and interests. The study's findings highlight that the Indonesian government, in alignment with the principles of the BRI, is actively utilizing the Jakarta-Bandung High-Speed Railway project to advance its New Developmentalism approach under President Jokowi's administration. This approach embodies a narrow perspective of development by focusing on infrastructure and economic growth while ignoring political and environmental considerations. Concurrently, the project has encountered resistance from local communities, underscoring the contrasting interests between the government and the public and adding a nuanced layer to the dynamics of the BRI. This case study sheds light on the complex interplay of interests and power dynamics within the context of China's BRI projects in the Global South. It underscores the importance of considering the responses and agency of host nations and local communities in shaping the outcomes of BRI initiatives.
Detection and quantification of splicing variants of Hd3a gene in oil palm
Authors: Polosoro Aqwin , Enggarini Wening , Kusumanegara Kusumawaty , Hadiarto Toto , Miftahudin Miftahudin , Supena Ence Darmo Jaya
Published: April 2024

Alternative splicing is a complex process that contributes to the generation of diverse mRNA and protein isoforms, including in oil palm (Elaeis guineensis). Despite their importance, many functions of alternative splicing genes remain poorly characterized. This study aims to investigate splicing variants of gene encoding Heading date 3a in E. guineensis (EgHd3a) using the GenBank database and ClustalW algorithm. To ensure the data accuracy and reliability of design isoform‐ specific primers, special emphasis is given to primer design techniques and validation using polymerase chain reaction (PCR) and quantitative real‐time (qRT)‐PCR analysis. The designed primers demonstrated high specificity and discrimination between mRNA specimens. Nucleotide variations at the 3’‐end influenced the specificity of primers with the addition of GC composition. Furthermore, qRT‐PCR analysis revealed a strong correlation between Ct values and gene concentration for the isoforms which indicates a reliable amplification of EgHd3a. Although two isoforms, Hd3a‐X2 and Hd3a‐X3, showed slightly higher than acceptable PCR efficiency values, caution is advised to prevent non‐specific amplification. Despite the challenge posed by the limitation of primer positioning due to alternative splicing, the chosen primer proved optimal for analysis. This study highlights the importance of considering alternative splicing in gene quantification experiments and provides insights into the critical steps, methods, and quality control measures necessary for accurately detecting alternative splicing events, contributing to understanding this complex biological process.
Arohynapene A Produced by Penicillium steckii JB-NW-2-1 Isolated from Avicennia marina (Forssk.) Vierh and Its Cytotoxic Activities
Authors: Mulyani Yeni , Syafriansyah Wahyu , Wulandari Asri Peni , Azhari Azmi , Purbaya Sari , Sari Aprilia Permata , Pratama Galih Bayu , Abdullah Fajar Fauzi , Farabi Kindi , Supratman Unang , Shiono Yoshihito
Published: April 2024

Mangrove-associated endophytic fungi are producers of secondary metabolites in unique and diverse structures with interesting biological activities such as antiviral, antifungal, antibacterial, anti-inflammatory, and cytotoxic agents. Endophytes play an important role in the physiological activities of the host plants, influencing the improvement of resistance to stress, insects, nematodes, and diseases. In this study, arohynapene A, a polyketide compound, was successfully isolated from the mangrove-derived fungus Penicillium steckii JB-NW-2-1 obtained from mangrove plant Avicennia marina (Forssk) Vierh. The structure was determined by a spectroscopic method including IR, MS, 1D-, and 2D-NMR techniques. This compound was evaluated for cytotoxic activities using resazurin assay against four cancer cells, HeLa cervical, MCF-7 breast cancer, B16-F10 melanoma, and A549 lung adenocarcinoma. The results showed no significant activities against all cancer cells tested (IC50 > 500 µM).
Distorted Reflections: Gender and Horror in ‘Black Swan’
Authors: Sengupta Sarada , Chowdhury Dr Anindita
Published: April 2024

In Black Swan, the themes of gender and horror are intricately woven into the fabric of the narrative. The film delves into the psychological nuances of its protagonist, Nina, as she navigates the demands of her art and the pressures of perfection. The exploration of gender identity and the inherent horror within the competitive world of ballet converge to create a compelling and thought-provoking cinematic experience. This paper aims to dissect the manifestations of gender dynamics and horror elements within the film, shedding light on their significance in shaping the narrative and character development. The analysis will encompass the contemporary ballet, femininity, Irigarayan horror, character interactions, and overarching themes that contribute to the film’s exploration of gender and horror. By examining these aspects, this study seeks to provide a deeper understanding of the complexities and nuances present in “Black Swan” while also showcasing the film’s prowess in challenging traditional tropes and expectations within the realm of both gender representation and horror storytelling.
IOT and AI Implementations on Remote Healthcare Monitoring System
Authors: Patil Vaishnavi
Published: April 2024

Abstract: "IoT and AI Implementations on Remote Healthcare Monitoring System using Raspberry Pi 3" seeks to revolutionize healthcare by integrating cutting-edge technologies into a cohesive system for remote patient monitoring. Leveraging the power of Raspberry Pi 3, Internet of Things (IoT) devices will be employed to collect real-time health data from patients in diverse locations. This data will then undergo sophisticated analysis through Artificial Intelligence (AI) algorithms, enhancing the system's ability to identify anomalies, trends, and potential health risks with a high degree of accuracy. The Raspberry Pi 3 serves as a versatile and cost-effective hub, managing the connectivity and processing requirements of the IoT devices. The system aims to provide continuous and proactive healthcare support by enabling remote monitoring of vital signs and timely interventions based on AI- driven insights. The outcomes of this project not only contribute to the advancement of healthcare technology but also address the growing need for scalable and accessible healthcare solutions in a rapidly evolving digital landscape.
Dukungan sosial teman sebaya dan resiliensi dengan stres akademik pada mahasiswa rantau tahun pertama
Authors: Alya Dwi Anggraeni  , Diana Savitri Hidayati
Published: April 2024

The number of universities in Java Island and the uneven quality of universities in Indonesia have resulted in the tendency of students to travel. Both academic and other adjustments, culture shock, communication difficulties can cause stress and anxiety. This also happens to first-year students who are in the stage of emerging adulthood where students will experience transitions that cause change and stress. Among the factors believed to impact academic stress levels are peer social support and resilience. The present study aimed to investigate the relationship between peer social support, resilience, and academic stress among first-year students from regional areas. The research sample consisted of 395 first-year undergraduate students (S1) from the University of Muhammadiyah Malang who originated from areas outside Greater Malang. Accidental sampling was employed as the sampling technique. The sampling technique uses accidental sampling. The research design used was correlational with spearman correlation analysis techniques and multiple correlations using SPSS 24. The results showed that the value of sig. F change of 0,142 > 0,05 means that there is no simultaneous or shared relationship between peer social support and resilience with academic stress. The implication of this study suggests that first-year regional students should actively maintain peer social support through frequent communication and engagement in campus activities to alleviate academic stress.
Penerapan psikodrama untuk meningkatkan kompetensi emosi pada remaja dengan orang tua bercerai
Authors: Ratmilia Cahyani  , Siti Suminarti Fasikhah
Published: April 2024

Adolescents who experience the impact of divorce experience unstable emotional conditions, sadness, disappointment, and low emotional competence. Emotional competence is the condition of an individual who is able to recognize, express, understand, regulate and use the emotions they feel. There are many ways to improve the emotional competence of teenagers with divorced parents, one of which is using the psychodrama method. Psychodrama is a way of expressing what is felt about the pressure or stress that is being experienced or method often called catharsis. The research aims to determine the use of intervention in the form of psychodrama in an effort to increase emotional competence in adolescents with divorced parents. This research uses an experimental approach with a pretest-posttest control group design. The instrument used was the Profile of Emotional Competence (PEC). There were 10 research subjects determined using a purposive sampling method who were then divided into experimental and control groups according to low to medium PEC scores. The results of data analysis using the Wilcoxon test showed that there was a significant difference in the experimental group (p= 0,043) and there was no significant difference in the control group (p= 0,069). Based on these results, it indicates that psychodrama has a significant influence in efforts to increase emotional competence in adolescents with divorced parents.