bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Cytotoxicity and Molecular Docking Studies of Phthalimide and Naphthalimide Derivatives as Potential Anticancer Agents
Authors:   Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Ahanj Negin , Taghavi Mehdi ,   Department of Medicinal Chemistry, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Mojaddami Ayyub ,   Department of Chemistry, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Published: March 2022

Background and Objectives Cancer is the second leading cause of death in the world after cardiovascular disease, so the aim of the present study was to investigate phthalimide and naphthalimide derivatives in order to develop anticancer compounds. Subjects and Methods In this study, the cytotoxic activity of six phthalimed and naphthalamide derivatives was evaluated using MTT method on three cancerous cell lines, including breast cancer (MCF-7), ovarian cancer (SKOV3) and lung cancer (A549) cell line. Molecular Docking studies were also performed to determine the binding energy and the compounds interaction with DNA as a possible target of these compounds. Results Based on MTT results, compound C1, a naphthalimide derivative, showed the highest cytotoxic activity. IC50 values of this compound against MCF-7, SKOV3 and A549 cancer cell lines were 1.7, 6.2 and 9.5 μM, respectively. Also, comparison of phthalimide and naphthalimide derivatives showed that compounds C1, C3, C5 with carboxyl group had better effects than other compounds, C2, C6, C4, which bearing 5-amidoisophthalic acid moiety. Conclusion In general, naphthalimide derivatives showed better cytotoxicity than phthalimide derivatives. Compound C1 has the highest cytotoxic activity on all three cancer cell lines and can be further studied in the development of new anti-cancer compounds.
The Effect of Chronic Kidney Disease Induction Upon Affective Factors on Muscle Apoptosis in Rats and the Role of Aerobic Training in Its Modulation
Authors:   Department of Exercise Physiology, Faculty of Sport Sciences, Kharazmi University, Tehran, Iran., Jafari Mahmood , Motamedi Pezhman ,   Department of Exercise Physiology, Faculty of Sport Sciences, Kharazmi University, Tehran, Iran., Khaledi Neda ,   Department of Exercise Physiology, Faculty of Sport Sciences, Kharazmi University, Tehran, Iran.
Published: March 2022

Background and Objectives Chronic Kidney Disease (CKD) is characterized by progressive and irreversible loss of renal function. One of the complications of this disease is muscle wasting and atrophy. The aim of this study was to determine the effect of exercise training on CKD-induced muscle apoptosis in rats. Subjects and Methods In the present developmental study, 30 rats were selected and divided into 3 groups: disease training, disease control and healthy controls. Induction of CKD was through primary and final 1.3 resection of one kidney and complete resection of the other kidney. The training program consisted of eight weeks of continuous running training with an intensity of 45-55% VO2max. After removal of EDL muscle, protein level and Bcl-2 and Bax gene expression were measured by immunohistochemistry and real-time PCR, respectively. Results Induction of CKD caused a significant increase in protein level and gene expression of Bax and Bax/Bcl-2 and a significant decrease in Bcl-2 compared to the healthy control group (P<0.001). Also significant decrease was funded in the expression of genes and proteins Bax and Bax/Bcl-2 (P<0.001) and a significant increase was funded in protein Bcl-2 (P<0.001), without significant changes in the gene expression of Bcl-2 (P=0.935) in disease training compared to the disease control. Conclusion The results of the present study support the anti-apoptotic effect of exercise on muscle tissue of CKD patients; therefore, it is recommended that clinical research be conducted in this regard for exercise recommendations for these patients.
Comparison of Total Salivary Antioxidants in Smokers and Non-smokers With Chronic Periodontitis
Authors:   Department of Periodontics, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., GolPasandhagh Leila , Bahadori Mahsa ,   Department of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Ghaffari Seyied Mohammad ,   Department of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Published: March 2022

Background and Objectives Periodontitis is an inflammatory disease that involves supporting tooth structure, can be affected by risk factors like smoking, and increase the prevalence and severity of periodontal damages. Antioxidant stress to target molecule and prevent from degeneration of normal cells. This study aimed to compare the salivary total antioxidant level in smokers and non-smokers with chronic periodontitis. Subjects and Methods A case-control study was performed in 60 chronic periodontitis patients (30 smokers and 30 non – smokers) in referral patients to Ahvaz Jundishapoor university of Medical Sciences, School of Dentistry. Saliva samples were collected from all subjects and the total salivary antioxidant level in these subjects measured with the spectrophotometry method in 600 nm wavelength. data analyzed with t-test statistical analysis. Results A significant difference between total salivary antioxidant level in smokers and non-Smokers patients with chronic periodontitis observed (P<0.001). Conclusion This study showed decreasing in total salivary antioxidant level in the smoker- patients with chronic periodontitis compared to non-smoker patients with chronic periodontitis.
Predicting Preventive Covid-19 Disease Behaviors Based on Health Literacy With the Mediating Role of Media and Social Responsibility in Adults Living in Ahvaz
Authors:   Department of Psychology, Institute for Higher Education ACECR, Khuzestan, Iran., Fathi keyhan , Shirmardi Sara ,   Department of Counseling, Faculty of Education and Psychology, Shahid Chamran University of Ahvaz, Ahvaz, Iran., Shiralinia Khadijeh ,   Department of Counseling, Faculty of Education and Psychology, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Published: March 2022

Background and Objectives One of the ways to deal with Covid-19 disease is 19 preventive behaviors that seem to be affected by different factors. Therefore, the aim of the present study was to predict the preventive behaviors of Covid- 19 disease based on health literacy with the mediating role of media information belief and social responsibility. Subjects and Methods This descriptive and correlational study was performed on 247 adults in Ahvaz in the summer of 2020. The research sample was selected using available sampling and they answered online the questionnaires whose validity and reliability were confirmed.. Data were analyzed using Spss, Amose software, descriptive and analytical statistics. Results The results showed that the indirect coefficients between believing in media information (P=0.000, β=0.04) and social responsibility (P=0.000, β=0.11) with preventive behaviors of corona disease were significant. The proposed research model also had a good fit (RMSEA= 0.05, P=0.20, X2/df: 1.63, X2: 1.63). Conclusion The results showed that health literacy is both directly and indirectly related to corona disease prevention behaviors through belief in media information and social responsibility. Therefore, to increase the preventive behaviors of corona disease in individuals, we can use the influence of the media and strengthen social responsibility in individuals.
Evaluation of Blood and CSF Isolated Bacteria and Their Antimicrobial Resistance in Hospitalized Patients in Ahvaz Golestan Hospital in 2020
Authors:   Department of Pathology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Fatahi Ladan , Einali Varnosefaderani Saeed ,   Department of Pathology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Published: March 2022

Background and Objectives: Infection of the blood and cerebrospinal fluid can have irreparable consequences and even death. In the present study, the prevalence of bacteria causing blood and cerebrospinal fluid infection and their antibiotic resistance in hospitalized patients was investigated. Subjects and Methods: In this present descriptive-cross-sectional study, the results of all blood and cerebrospinal fluid samples were sent for culture from the hospitalized patients of Golestan Hospital in Ahvaz in the first six months of 2019 were examined. Relevant information was extracted from patients’ medical records. Results: In this study, 12.17% of blood culture were positive and 7.6% of cerebrospinal fluid culture were positive. The most common bacteria causing blood infections were Staphylococcus Coagulase Negative (32.5%), Klebsiella (24.1%) and Pseudomonas (21.7%), and the most common bacteria causing cerebrospinal fluid infection were Klebsiella (30.9%), Streptococcus. group D (Enterococcus) (20.6%) and pseudomonas (15.5%). The highest bacterial resistance was observed for Ampicillin, Ceftriaxone, Cefazolin, Cefixime and Cefotaxime antibiotics, and the highest sensitivity was observed for Meropenem, Colistin, and Levofloxacin antibiotics. Conclusion: Since the bacterial resistance pattern is always changing, it is suggested that before starting any empirical treatment in infectious diseases, sensitive antibiotics for common bacterial agents are recommended for a more efficient treatment.
Effect of Maternal Training Before and During Pregnancy on the Lipid Profile in Wistar Rat Offspring
Authors:   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, kharazmi University, Tehran, Iran., Mohammadkhani Reihaneh , Rajabi Hamid ,   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, kharazmi University, Tehran, Iran., Khaledi Neda ,   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, kharazmi University, Tehran, Iran., Komaki Alireza ,   Department of Physiology, Research Center of Neurophysiology, Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran, Salehi Iraj ,   Department of Physiology, Research Center of Neurophysiology, Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran.
Published: March 2022

Background and Objectives The fetal period is an important stage in a person’s life. Exercise during pregnancy has been considered as a positive factor in preventing chronic diseases in adulthood. The aim of this study was to investigate the role of maternal high intensity exercise before and during pregnancy on serum levels of lipid profile of adult offspring. Subjects and Methods Twenty-four rats (170-200g) were divided into three maternal groups: Control (C), exercise Before Pregnancy (BP) and exercise before and during pregnancy (BDP). Exercise performed before pregnancy for six weeks and during pregnancy for three weeks; one minute with 80% -95% vo2max switching with two minutes of active recovery (65% vo2max) for five days/week. After end of the training birth process and breastfeeding, the offspring were divided according to theirs’s mother group and they were kept until adult age. The serum levels of LDL, HDL, TG and Cho were measured by enzymic method. Results The one-way ANOVA result showed that maternal exercise before and during pregnancy significantly reduced LDL, Cho and LDL/HDL cholesterol ratio in male (P=0.03, P=0.2, P=0.04) and female (P=0.00, P=0.02, P=0.04) offspring. Conclusion This finding suggests that maternal high-intensity-interval training as an appropriate environmental intervention can help to improve the health of the next generation.
Analysis of thiosemi carbazon complexes effects on UCA1 lncRNA and AKT target, gene expression alternations, regulating PI3K/ AKT signaling pathway in Jurkat E6.1 Acute Lympholastic Leukemia cell line
Authors:   Msc of molecular genetic,Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan , Iran, daneshi faranak , ghorbani fatemeh ,   Msc of molecular genetic,Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan , Iran, asadi tehrani golnaz ,   Msc of molecular genetic,Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan , Iran, mirza ahmadi azadeh ,   PhD in Chemistry, Department of Chemistry, University of Tabriz, Tabriz, Iran
Published: March 2022

Background and Aim:Leukemia usually begins in the bone marrow and leads to the production of a large number of abnormal white blood cells.The goal of this study was to investigate changes on UCA1 lncRNA and AKT target, gene expression alternations, regulating PI3K/ AKT signaling pathway in Jurkat E6.1 Acute Lympholastic Leukemia cell line under treatment with thiosemicarbazone complexes(nickel). Materials and Methods: First, thiosemicarbazones complex Ni and 6MP was provided in different concentrations(0.5,1,2,5macromolecular)and(1,5,10,25macromolecular) and the jurkat E.6.1 Cancer cells were treated with mentioned doses at (24-48-72hours)after cell passage. Next RNA extraction and cDNA synthesis were performed and the expression of UCA1 and AKT gene were appraised by Real Time PCR. Finally, the results were analyzed by Rest Software. Results:UCA1 showed a significant decrease during 24hours of treatment with 6mp at concentrations(1,5,10and25macromolecular)(P<0.001).In nickel,a significant decrease at 72hours was observed at concentrations(2and 5macromolecular).in the AKT in treatment with 6mp at 24hours At concentrations(5,10and 25macromolecular)And all concentrations(1,5,10and25macromolecular)at 72hours showed a significant decrease(P<0.001).In nickel at concentrations(0.5,1,2and5macromolecular)at 24hours Decreased expression was observed,This decrease is not statistically significant at a concentration of 0.5μM.at concentrations(2and 5macromolecular)Significant reductions at 48and72hours were observed(P<0.001). Conclusion:UCA1 and AKT expression changes after treatment with 6mp and nickel depend on drug timing and concentration.UCA1 in 6MP treatment at 25μM and 24hours,in treatment with nickel at 5μM and 72hours , AKT in 6mp treatment at 25μM and 72hours , In treatment with nickel at 5μM and 24hours,It had the highest effect on the cell due to gene expression.
Survey of Frequency, Clinical Characteristics and Causes of Seizure in Children Younger Than Five Years With Acute Gastroenteritis Admitted to Ahvaz Golestan Hospital Over a Two Year Period
Authors:   Department of Pediatrics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Momen Ali Akbar , Asar Shideh ,   Department of Pediatrics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Heydar Azadeh Maryam ,   Department of Pediatrics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Karimi Ghasem ,   Department of Pediatrics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Published: March 2022

Background and Objectives Acute gastroenteritis is a highly prevalent disease in children. Various factors may causes seizure in children with gastroenteritis. This study was designed to determine the frequency, clinical characteristics and causes of seizure in children younger than 5 years with acute gastroenteritis admitted to Ahvaz Golestan hospital. Subjects and Methods In a retrospective descriptive study based on hospital records , 339 children under 5 years old who were admitted to Ahvaz Golestan hospital during 2016 - 2017 were assessed. Patients with underlying neurological disorders were excluded and the recorded information of patients with seizure was reviewed. Results Out of 339 reviewed cases, 59 patients (17.4%) had seizures, most prevalent in13 to 24 months age group (28.8%). In 74.6% of cases, type of diarrhea were dysentery. 64.4% had mild dehydration. Encephalopathy was detected in 1.7%, shigellosis in 6.8%, hyponatremia in 32.2% and hypernatremia in 3.4%. Seizures in 52.5% of cases were considered as febrile Seizure. Diagnostic criteria of benign convulsions associated with mild gastroenteritis (CwG) were present in 5% of patients. 79.7% of cases had generalized seizures. In comparison, a significant relationship was observed between the febrile and non-febrile groups only in the variable of diarrhea type. Conclusion The results show that fever and electrolyte imbalances and among infectious agents, Shigella are important causes of seizures in patients with gastroenteritis. In patients with dysentery, seizures are more likely.
The effect of sixteen weeks of functional training on quality of life and mental health in military personnel
Authors:   Department of Physical Education and Sport Science, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran, Ahmad Baladi Saeed Rahimi , Tadibi Vahid ,   exercise physiology, School of Sport Sciences, Razi University, Kermanshah, Iran., Hosseeinpoor Delavar Sedigheh ,   Department of physical education and sport science, Kermanshah branch, Islamic Azad University, Kermanshah, Iran., Amiri Ehsan ,   Department of Exercise Physiology, School of Sports Sciences, Razi University, Kermanshah, Iran, Jalilvand Mohammad ,   Department of Physical Education and Sport Science, kermanshah Branch, Islamic Azad University, Kermanshah, Iran
Published: March 2022

Background and Aim: Military personnel are exposed to some work stress due to their working conditions, which causes negative effects on their quality of life. The aim of this study was to investigate the effect of sixteen weeks of functional training on quality of life and mental health of military personnel. Research method: In the present Quasi-experimental research, 150 military personnel from Andimeshk and Dezfoul sities were selected by random sampling method and divided in two training and control groups. Exercise was performed for sixteen weeks of functional training, three sessions per week, and each training session lasted about 60-90 minutes. T-test was used for statistical analysis. Results: After the training period, there was a significant improvement in the quality of life sub-comparisons of physical function, physical role, emotional role, energy and vitality, social function, physical pain, and general health in the functional training group compared to the control group, but the difference No significance was observed in cognitive health between the two groups. In the subscales of mental health, a significant improvement in physical symptoms, anxiety symptoms and sleep and social dysfunction was observed in the functional exercise group compared to the control group, but a significant difference in changes in depressive symptoms was observed in the functional exercise group compared to the control group. Failed. Discussion and Conclusion: According to the findings of the present study, it can be said that functional exercises have improved the quality of life of military personnel by improving their mental health.
The impact of a cardiac rehabilitation course on BDNF level changes and functional capacity in acute myocardial infarction patients
Authors:   Department of Physical Education and Sport Sciences, Islamic Azad University, Isfahan Branch (Khorasgan), Olamazadeh Mohamadhassan , Sharifi Gholamreza ,   Department of Physical Education and Sport Sciences, Islamic Azad University, Isfahan Branch (Khorasgan), gharipour mojgan ,   Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran, Sadeghi Masoumeh ,   Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran, khosravi elham ,   Hypertension Research Center, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Olamazadeh shiva ,   Department of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran, sadeghian ladan ,   Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran., Ahmadi Ali ,   Department of Physical Education and Sport Sciences, Islamic Azad University, Isfahan Branch (Khorasgan). Isfahan. Iran
Published: March 2022

Background: Acute myocardial infarction refers to a reduction or amputation of coronary artery circulation leading to myocardial necrosis. BDNF is expressed in atherosclerotic arteries, vascular smooth muscle, and endothelial cells and is involved in angiogenesis, the inflammatory response, and apoptosis of myocardial regeneration after infarction. The aim of this study was to evaluate the effect of a cardiac rehabilitation period on changes in BDNF levels and functional capacity in patients with acute myocardial infarction. Methods: The present study was performed on 30 men with acute coronary syndrome with a pretest-posttest design and the samples were randomly divided into experimental and control groups. The experimental group performed a cardiac rehabilitation program for 6 weeks. The control group did not perform any training during this period. Before and after the rehabilitation program, BDNF levels were measured by the American Diaplus Kit in terms of picograms per milliliter and participants' functional capacity by a modified Bruce test. Analysis of covariance was used to compare BDNF levels and functional capacity of cardiac rehabilitation and control groups. Discussion & Conclusion: Data were analyzed by covariance and the results showed that cardiac rehabilitation training had a significant effect on increasing BDNF levels and functional capacity (P≤0.05). In general, it can be said that cardiac rehabilitation exercise program can play an important role in improving the physical and physiological condition of patients with acute myocardial infarction.
Determining the Frequency of Hearing Loss and Its Risk Factors in Neonates Admitted to the Neonatal Unit: A Hospital Study
Authors:   Department of Audiology, School of Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran., Delfi Maryam , Goodarzi Elena ,   Department of Pediatrics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Hardani Amir Kamal ,   Department of Pediatric, Faculty of Medicine, Abuzar Academic and Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Badfar Gholamreza ,   Department of Pediatric, Faculty of Medicine, Abuzar Academic and Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: March 2022

Background and Objectives The prevalence of hearing loss in infants with a risk factor is higher than in infants without a risk factor. The aim of this work is determine the prevalence of hearing loss and identify the most significant risk factors for hearing impairment in neonates hospitalized at neonates unit. Subjects and Methods A total of 450 infants admitted to the neonatal unit of Abuzar hospital in Ahvaz were evaluated for hearing in October 2020 to April 2020. The hearing screening tests performed were Transient Evoked Otoacoustic Emissions (TEOAES) and the automated auditory brain stem response (AABR). Risk factors include birth weight less than 1500g, prematurity, family history of hearing loss, consanguineous marriage, hyperbilirubinemia, mechanical ventilation for more than 5 days, asphyxia, autotoxic drugs, sepsis, hypoglycemia and Apgar less than 5 were in one minute after birth. Results twenty neonates (4.4%) had different type of hearing loss. Mechanical Ventilation more than 5 days, sepsis, asphyxia, hyperbilirubinemia and Apgar<5 were considered risk factors of hearing loss. Conclusion The prevalence of hearing loss in neonate with risk factor is significant that raises the need for hearing screening using TEOAE and AABR simultaneously. It is recommended that children with hearing loss risk factors be evaluated for hearing periodically.
The Effect of Q10 Supplementation on Lipid and DNA Degradation Indices Following an Acute Physical Activity
Authors:   Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Islamic Azad University, Karaj Branch, Alborz, Iran, Bazeh Babak , Jafari Afshar ,   Department of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti Univercity, Tehran, Iran, Malekirad Aliakbar ,   Department of Biology, Faculty of Basic Science, Payame Noor University, Tehran, Iran.
Published: March 2022

Background and Objectives The use of antioxidant supplements improves and reduces oxidative stress factors following intense intense exercise. Exhaustion was performed in female athletes. Subjects and Methods 14 female athletes with an age range of 20 to 28 years and a maximum oxygen consumption of 42-52 m/kg/min in a quasi-experimental design randomly divided into two groups receiving coenzyme Q10 supplementation and placebo (5 mg/kg body weight). Were. After 14 days of coenzyme Q10 supplementation, the subjects performed an intense, debilitating activity. Urine samples were collected in three stages (baseline, before and 24 hours after exhaustive activity) to determine the concentration of 8-OHdG and MDA. Results There was a significant difference of 62% in the increasing response of urinaryOHdG-8 to an exhausting aerobic exercise session (P = 0.003). However, the 2% difference in the increasing urinary MDA response of the supplement and placebo groups was not significant after the last quasi-competitive aerobic training session (P = 0.7). Conclusion According to the results of the study, two weeks of high-pressure aerobic training causes DNA damage and lipid peroxidation in female athletes, and supplementation with Q10 helps prevent the 8-OHdG response of female athletes after a strenuous high-pressure aerobic training session and reduces DNA damage. Become athlete
Demographic, Clinical, and Radiological Characteristics of Patients With Hydatid Cyst Refereed to Ahvaz Hospitals During 2017-2019
Authors:   Department of Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Mirzavand Somayeh , Beiromvand Molouk ,   Department of Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Rafiei Abdollah ,   Department of Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Bahreini Amin ,   Department of Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Cheraghiyan Bahman ,   Department of Biostatistics and Epidemiology, School of Health, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran, Motamedfar Azim ,   Department of Radiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Abdolhadi Jahanshahi Alireza ,   Department of Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: March 2022

Background and Objectives Hydatid cyst is a worldwide zoonotic disease caused by the larval stages of Echinococcus granulosus. The aim of this study was to investigate the demographic, clinical and radiological characteristics of hydatidosis patients undergoing surgery in hospitals in Ahvaz during Subjects and Methods This study is a retrospective descriptive cross-sectional study based on the information recorded in the patients' files. Data were analyzed using SPSS software, descriptive statistics and Chi-square test. Results Of the 107 patients with a mean age of 36.78 years, 42.1% were male and 57.9% were female. The highest frequency was related to the age group of 31-40 and the lowest was related to the patients under 10 years old. 52.3% lived in the rural areas and 47.7% lived in the urban areas. In 70.1% of the patients, liver was involved and recurrence was reported in 14%. In 59.8% of the patients, only one cyst was reported and in 40.2% more than one cyst was reported. The cysts size was 10 to 180 mm and about 50% of the patients had CE2 cysts. The diagnostic method of all patients was imaging techniques and drainage method was the most common method used. Conclusion This study showed that hydatid cyst in Khuzestan Province is still one of the important health problems that raise the need for educational programs based on the prevention and control of parasitic infections, especially parasites transmitted by dogs. Observation of 14% recurrence also raises the importance of choosing the appropriate surgical method by surgeons.
Evaluation of Periodontal Status in Patients With Chronic Renal Disease
Authors:   Department of Periodontal Dentistry, Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, GolPasand Hagh Leila , Ariankia Azarnooshَ ,   Department of Periodontal Dentistry, Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Shahbazian Heshmatollah ,   Department of Periodontal Dentistry, Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: March 2022

Background and Objectives Most renal patients have various oral manifestations such as halitosis, xerostomia and pale mucosa. The purpose of this study was to evaluate the relationship between periodontal status and chronic renal disease. Subjects and Methods In this case-control study, the case group was divided into three subgroups, which included renal patients before dialysis, patients undergoing hemodialysis, and patients after renal transplantation, each of which included 23 patients. The control group also included 38 healthy individuals in terms of renal function. After obtaining the consent form and completing the questionnaire, the amount of plaque index, gingival index, papillary bleeding index, probing depth, loss of clinical attachment, gingival recession and gingival enlargement were measured T-student,chi-square. and Anova was used to analyze the data. Results The plaque index, gingival index, papillary bleeding index, probing depth, loss of clinical attachment in groups with chronic renal disease were higher than the control groups (P< 0.001) but there was no significant difference in gingival recession and gingival enlargement between control group and case groups (P> 0.05 ) . These parameters were not significantly different between the groups with chronic renal disease (P> 0.05). Conclusion Periodontal disease is more common in patients with chronic renal disease, therefore, special periodontal treatment considerations and regular dental examinations should be added to the treatment plan of these patients.
The Effect of Educational Intervention Based on Health Belief Model on Blood Pressure Control in Patients With Hypertension Referring to the Clinic of Shariati Hospital in Isfahan 2017-2018
Authors:   Department of Midwifery, School of Medicine, Arak University of Medical Sciences, Arak, Iran, Shojaeifar Samaneh , Shojaeifar Hamed ,   Department of Medicine, School of Medicine, Najafabad Branch, Azad University, Najafabad, Iran, Sobhani Ahmad ,   Department of Medicine, School of Medicine, Najafabad Branch, Azad University, Najafabad, Iran
Published: March 2022

Background and Objectives Hypertension is the most important risk factor for death and Cardiovascular diseases (CVDs). Blood was referred to the clinic of Shariati Hospital in Isfahan in 2017-2018. Methods Hypertension is the most important risk factor for death and CVDs. Blood was referred to the clinic of Shariati Hospital in Isfahan in 2017-2018 The present study was a clinical trial with a pre-test and post-test design with a control group. 90 patients with hypertension referred to the internal clinic of Shariati Hospital were randomly divided into two groups of 45 people (control and intervention). The intervention group, training based on health belief model and the control group performed routine training. Data collection tools included a health belief model questionnaire, a pamphlet and an educational booklet that was presented to each member of the individual education intervention group in two sessions two months apart. In the second visit, blood pressure of all patients was taken by the student and questionnaires were completed by the patients after the intervention. Results The results showed that there was a statistically significant difference between the mean of the main indicators of sensitivity, severity, benefits and barriers in the intervention and control groups before and after the intervention (P<0.05). Conclusion It seems that the health model is effective in controlling blood pressure in patients with hypertension.
Evaluation and Comparison of the Antioxidant Activity of Extractable Polyphenols and Non-extractable Polyphenols of Sour Orange Peel
Authors:   Medicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Rezaei Zahra , Siahpoosh Amir ,   Department of Pharmacognosy, Faculty of Pharmacy, Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: March 2022

Background and Objectives Research on food polyphenols has experienced a huge development during the last century. Most studies on polyphenolic compounds have focused on extractable polyphenols (EPP). However, an important polyphenolic fraction is ignored (Non-Extractable polyphenols (NEPP)) because they are trapped in the corresponding extraction residues. In this study, the antioxidant EPP and NEPP of sour orange peel, extracted by aqueous solvent and acid hydrolysis (with two different solvent systems) respectively, are evaluated and compared. Methods Antioxidant activity was evaluated by four tests of radical inhibition of 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2, 2-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), ferric reducing antioxidant power (FRAP) and iron chelating. The amount of polyphenolic compounds, flavonoids, oligomeric proanthocyanidins, and flavanones were respectively determined by folin-ciocalteu, Aluminium chloride (AlCl3) and Ultraviolet–visible spectroscopy (UV-visible). Also, the anti-lipid peroxidation effect in rat liver was measured. Results The results of antioxidant analysis showed that NEPP with methanol/Sulfuric Acid Solvent had the highest level of antioxidant activity in sour orange peel. It can be due to the high polyphenolic compounds in this extraction compared to the others. Conclusion All extracts had antioxidant activity and can be suggested as a potential natural source in food and pharmaceutical industries.
Evaluation of Different Biochemical Factors in Patients With Coronavirus Disease in Imam Khomeini Hospital of Selseleh County (Lorestan Province)
Authors:   Department of Biology, Faculty of Science, Lorestan University, Khorramabad, Iran, Bahramikia Seifollah , Gavyar Parvaneh Hemmati Hassan ,   Department of Biology, Faculty of Science, Lorestan University, Khorramabad, Iran, Amiri Sana ,   Internal Medicine Ward, Imam Khomeini Hospital of Selseleh, Lorestan University of Medical Sciences, Khorramabad, Iran
Published: March 2022

Background and Objectives Coronavirus disease is a large family of viruses and subtypes of coronavirus that range from the common cold virus to more serious illnesses such as SARS, Mers, and Covid. Symptoms of a new coronavirus that causes Coronavrus Disease 2019 (COVID-19) usually begin a few days after a person becomes infected with the virus. But in some people, the symptoms may appear a little later. According to statistics and research, symptoms can include fever (in 43.8% of people at admission and 88.7% in hospitalized), dry cough, and shortness of breath. In addition to these clinical symptoms, after exposure to the virus, a series of blood factors change, and the measurement of these factors helps to treat and prevent the progression of the disease. This study aimed to investigate the changes in various blood factors in coronary patients admitted to Imam Khomeini Hospital in Selseleh, Lorestan. Methods In this study, biochemical tests of 50 coronary patients, including 30 males and 20 females ranging in age from 30 to 90 years, were performed. Factors examined included White blood cell (WBC), Red blood cell (RBC), hemoglobin, platelets, lymphocytes, Erythrocyte sedimentation rate (ESR), C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine kinase-MB (CK-MB). Results The results showed that among the mentioned factors, the number of lymphocytes in all patients decreased compared to the normal range, and the amount of ESR, CRP, CK-MB, and LDH factors increased compared to the normal range. Conclusion Considering that the present study was performed at the beginning of the corona disease and the number of hospitalized people as well as hospital facilities was low, it is better to study the population in relation to a much larger population and also perform more complementary tests to conclude to conclude and evaluate the relevant parameters and the relationship between the parameters.
Measurement of Lead Concentration in the Blood of Patients Undergoing Appendectomy and Cholecystectomy
Authors:   Department of General Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Mohammadi Armin , Ghorbani Ahmad ,   Department of General Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Kargar Mohammad ,   Department of General Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Kazemnia Khalil ,   Department of General Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Published: March 2022

Background and Objectives Lead poisoning is a life-threatening condition due to its acute and chronic effects.Therefore, preventive methods are very important to prevent the multiple toxic effects of this metal.Due to the lethal effects of lead and its increasing concentration in the environment, this study was designed and performed to measure the concentration of lead in the blood and tissue of patients undergoing appendectomy and cholecystectomy. Methods In a cross-sectional study that was performed on patients with appendectomy or cholecystectomy in Razi Hospital in Ahvaz during a period of twelve months from May 2019 to May 2020. We examined 120 patients in three groups of appendectomy (n=40), cholecystectomy (n=40) and control (n=40).Blood samples were taken from all three groups. Then, after the operation, a pathology sample was taken from the appendix or gallbladder from patients in two groups who underwent appendectomy and cholecystectomy. X-ray Imaging was used to check for lead. Results Our results show well the mean blood lead concentration in the appendectomy group. In the cholecystectomy group and in the control group, the difference between the three groups was statistically significant (P<0.001). Also, lead was found in 21 samples (52.5%) from the appendectomy group and lead in 23 samples(57.5%) from the cholecystectomy group, but this difference was not statistically significant. (P= 0.175). Conclusion Based on the results of this study, it can be said that chronic exposure and lead poisoning may play a role in the occurrence and change of gallstones and appendicitis.
evaluation of contrast alternation efficacy in diagnosis of vertical root fracture in conventional digital radiography
Authors:   Assistant Professor of Radiology, Jundishapur Dental School . Ahvaz . Iran, Habibi kia Ali , Javaheri Mohammadamin ,   Faculty of Dentistry,, Ahvaz Jundishapur University of Medical Sciences,, Ahvaz,, Iran., dabaghi arash ,   Assistant Professor of Radiology, Jundishapur Dental School . Ahvaz . Iran, sabaghian mehdi ,   Assistant Professor of Department of Oral and Maxillofacial Pathology, Jundishapur Dental School . Ahvaz .Iran
Published: March 2022

Background and objective: Most digital imaging systems today offer a variety of image processing techniques. Due to the importance of the accuracy of this imaging and its widespread use in this study we investigate the effect of contrast change in the diagnosis of vertical root fracture in conventional digital radiography. Materials and methods: in this in vitro study 24 human single-rooted teeth induced vertical root fracture with underwent vrf. Digital images were prepared before and after induction vrf. Images with three low, medium and high contrasts were examined by two radiologists.Data were tested using kappa and MacNemar tests in SPSS software. Overall accuracy was calculated using Roc curve analyzes. Results: The highest sensitivity specificity and overall accuracy are related to images with moderate contrast (95.83%, 100% and 98% in the first observer and 100%, 100% and 100% in the second observer, respectively). In case of low and high contrast to detect vertical root fracture, there is no statistically significant difference with reality (p<0/001). Conclusion: Medium contrast can be used as a processing filter in the detection of vertical root fractures.
Comparison of the complications and recurrence rate after herniorrhaphy by open and laparoscopic methods in pediatric patients: A case-control study
Authors:   Department of General Surgery, School of Medicine, Nursing Care Research Center in Chronic Diseases, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical sciences, Ahvaz, Iran., Peyvaste Mehran , Askarpour Shahnam ,   Department of General Surgery, School of Medicine, Nursing Care Research Center in Chronic Diseases, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical sciences, Ahvaz, Iran., Sherafatmand Shaghayegh ,   Department of General Surgery, School of Medicine, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical sciences, Ahvaz, Iran., Toghyani Dolatabadi Mazdak ,   School of Medicine, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical sciences, Ahvaz, Iran.
Published: March 2022

Introduction: Indirect inguinal hernias in children are causing by the opening of the vaginal process and the entry of viscera into it. To compare the rate of complications and recurrence after open and laparoscopic hernia surgery. Methods: In this case-control study, the patients who underwent surgery by laparoscopic and open methods for 2018-2020 years. The data were extracted from a checklist based on the variables sex, age, infection rate, side effect, hydrocele rate, scar length, testicular swelling rate, and rate and recurrence. Results: A total of 261 patients were examined. The results showed that there was a statistically significant difference between the time of surgery in both surgical methods (Z = -9.903, p < 0.001). There is a significant statistical relationship between recurrence and surgical procedure (p = 0.021). None of the patients in the study had a positive infection, positive hydrocele, and positive testicular swelling after surgery. Conclusion: Both methods are safe that can be selected according to the patient's condition. It is recommended that further clinical studies be performed to evaluate and compare these two surgical procedures.
Explaining the Antecedents Vaginismus and Dyspareunia Disorder in Women: A Qualitative Study
Authors:   Department of Counseling, Faculty of Humanities, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran, Heydarian Maryam , Gholamzadehjefreh Maryam ,   Department of Counseling, Faculty of Humanities, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran, Shahbazi Masoud ,   Department of Counseling, Faculty of Humanities, Masjed Soleiman Branch, Islamic Azad University, Masjed Soleiman, Iran
Published: March 2022

Background and Objectives vaginismus and Dyspareunia disorders is important issue in the field of pain because this type of pain is part of emotional behaviors in marital relationships such as sexual intimacy and vaginal intercourse. The aim of the present study was to investigate the antecedents that lead to the experience of vaginismus and Dyspareunia in women. Methods This study was conducted with a qualitative approach and using the method of contractual content analysis with inductive method. 9 female participants with vaginismus and Dyspareunia were selected by purposive sampling method and continued to saturate. After data collection, all interviews were implemented and reviewed and the main components were extracted. First, the semantic units were identified and then turned into psychological expressions. Finally, the general structure was determined and combined. Results In general, thirteen predictive categories were identified using research data analysis. Accordingly, the preceding categories of this experience include incorrect family sex education, incorrect religious attitude, sexual abuse, phobia, fatigue, lack or insufficiency of sexual awareness, sexual disorders of the spouse, psychological disorders of the spouse, fear of pregnancy, Lack of foreplay, suppression of sexual desire, previous failed marriage and viewing pornographic images. Conclusion The results of this study enrich the previous research literature on the antecedents of the lived experience of vaginismus and dyspareunia. Also, the structure of living experience of vaginismus and Dyspareunia extracted in this study is widely used to develop and implement prevention and treatment programs for this disorder.
Changes in Insulin-Like Growth Factor 1 and Quadriceps Muscle Size in Follicular Stage Compared to Luteal Stage in Adaptation to Resistance Training in Young Women
Authors:   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran, Masjedi Hamid , Rajabi Hamid ,   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran, Motamedi Pezhman ,   Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran
Published: March 2022

Background and Objectives Menstrual cycle may affect the training of strength and muscle size. The aim of the present study was to determine the effect of exercise volume distribution in the 2 follicular and luteal phases of the menstrual cycle on serum Insulin-like Growth Factor 1 (IGF-1) and muscle mass in women. Methods in this semi experimental study’ 20 amenorrheic women with a mean age of 22±5 years, without contraceptive use and a history of eight weeks of resistance training were selected. Each subject had 8 training sessions on one leg in the first 14 days of menstruation and 2 training sessions on the second 14 days of menstruation (training in the follicular period) and the other leg had 2 training sessions on the first 14 days of menstruation and 8 training sessions on the second 14 days of menstruation (training in the luteal period). The training protocol was consist of unilateral leg extension. Results the quadriceps Muscle diameter (according to pretest size) in follicular training (FT) (0.67±0.34 (cm)) was higher than luteal training(LT) (0.46, 0.41 cm) (P=0.012). Also, insulin-like growth factor increased in both groups (13%) regardless of the type of exercise schedule (P> 0.001). Conclusion According to this study it is recommended that follicular based training may cause more muscle hypertrophy and maximum strength than luteal based training in young amenorrheic women who do not take birth control pills.