bluuebunny/crossref_metadata_2025 huggingface dataset:
Ten Tips and Tricks for Performing Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy
Authors: Veselka Josef
Published: April 2020

Alcohol septal ablation (ASA) is an effective interventional therapeutic strategy to reduce or eliminate left ventricular outflow tract obstruction in patients with hypertrophic obstructive cardiomyopathy (HOCM). Although ASA was introduced 25 years ago, there are still no available guidelines to follow. Therefore, most interventional cardiologists rely on their own experience, which is often limited by a relatively low number of performed procedures. This paper presents ten tips and tricks to safe and effective ASA for HOCM.
Networking: Gegenseitige Unterstützung in Krisenzeiten
Authors: Bannwarth Ralf
Published: April 2020

Eine gute Vernetzung und überregionale Netzwerke sind – unabhängig von Einkaufsgemeinschaften, Konzernen und Trägerschaften – Basis für ein effektives Arbeiten im Krankenhauseinkauf, um den Spagat zwischen steigenden Anforderungen, zunehmender Komplexität und stetig wachsendem wirtschaftlichen Druck gerecht zu werden.
Shocklets in the comet Halley plasma
Authors: Naeem Ismat , Ehsan Zahida , Mirza Arshad M. , Murtaza G.
Published: April 2020

Dust acoustic (DA) waves evolving into shocklets are investigated in the comet Halley plasma system relaxing to Maxwellian, Kappa, and Cairns distributions. Here, dynamics of dust is described by the fully nonlinear continuity and momentum equations. A set of two characteristic wave nonlinear equations is obtained and numerically solved to examine the DA solitary pulse that develops into oscillatory shocklets with the course of time such as at time τ=0, symmetric solitary pulses are formed, which develop into oscillatory shocklets. It has been observed that the variation in superthermality strongly affects the profiles of nonlinear DA structures in terms of negative potential, dust velocity, and density.
Efficient Langevin dynamics for “noisy” forces
Authors: Arnon Eitam , Rabani Eran , Neuhauser Daniel , Baer Roi
Published: April 2020

Efficient Boltzmann-sampling using first-principles methods is challenging for extended systems due to the steep scaling of electronic structure methods with the system size. Stochastic approaches provide a gentler system-size dependency at the cost of introducing “noisy” forces, which could limit the efficiency of the sampling. When the forces are deterministic, the first-order Langevin dynamics (FOLD) offers efficient sampling by combining a well-chosen preconditioning matrix S with a time-step-bias-mitigating propagator [G. Mazzola and S. Sorella, Phys. Rev. Lett. 118, 015703 (2017)]. However, when forces are noisy, S is set equal to the force-covariance matrix, a procedure that severely limits the efficiency and the stability of the sampling. Here, we develop a new, general, optimal, and stable sampling approach for FOLD under noisy forces. We apply it for silicon nanocrystals treated with stochastic density functional theory and show efficiency improvements by an order-of-magnitude.
Via resistance and reliability trends in copper interconnects with ultra-scaled barrier layers
Authors: Lanzillo Nicholas A. , Motoyama Koichi , Huang Huai , Robison Robert R. , Spooner Terry
Published: April 2020

We present a combined experimental and theoretical study of via resistance modulation in Cu interconnects with ultra-scaled diffusion barriers and wetting layers. In particular, we demonstrate that reducing the thickness of the TaN-based diffusion barrier below 1 nm results in a decrease in the measured via resistance, while reducing the thickness of the Co wetting layer below 1 nm has virtually no impact on via resistance. These results are explained using first-principles transport calculations, which show that a 1 nm thick TaN layer is more effective in blocking electrons than a 1 nm thick Co layer. Measurements of time-dependent dielectric breakdown indicate that scaling either TaN or Co layers below 1 nm in thickness results in degraded reliability. These results suggest that there is minimal value in scaling the thickness of Co wetting layers below 1 nm, while scaling TaN diffusion barriers below 1 nm results in a trade-off between performance and reliability.
Backside passivation for improving the noise performance in CMOS image sensor
Authors: Sun Peng , Hu Sheng , Zou Wen , Wang Peng-Fei , Chen Lin , Zhu Hao , Sun Qing-Qing , Zhang David Wei
Published: April 2020

Great efforts have been made in the past few years to reduce the white pixel noise in complementary metal–oxide–semiconductor (CMOS) image sensors. As a promising approach, the surface passivation method focusing on the field-effect passivation has been studied in this work. Based on the metal–oxide–semiconductor capacitor device model, electrical measurement and analysis have been performed for characterizing the charge distribution in the system. The relationship between the flat band voltage and the white pixel performance has been set up, and the proposed passivation method that controls Si or SiO2 interface charge or traps has been proved effective in lowering the white pixel noise, which can be very attractive in improving the performance of CMOS image sensors for high-resolution and high-sensitivity applications.
MAPK-directed activation of the whitefly transcription factor
CREB
leads to P450-mediated imidacloprid resistance
Authors: Yang Xin , Deng Shun , Wei Xuegao , Yang Jing , Zhao Qiannan , Yin Cheng , Du Tianhua , Guo Zhaojiang , Xia Jixing , Yang Zezhong , Xie Wen , Wang Shaoli , Wu Qingjun , Yang Fengshan , Zhou Xuguo , Nauen Ralf , Bass Chris , Zhang Youjun
Published: April 2020

Significance

Most studies of pesticide resistance have focused on the identification and functional analysis of resistance genes, but few studies have considered the signaling pathways involved in their regulation. In this work, we discovered that overexpression of a P450 that confers resistance to neonicotinoid insecticides in whitefly is
trans
-regulated by the transcription factor
CREB
. Further studies demonstrated that exposure to neonicotinoid insecticides activates a key pathway involved in the cellular response to extracellular signals, the MAPK signaling pathway, that activates
CREB
by phosphorylation.
CREB
then binds to a specific site on the promoter of
CYP6CM1
resulting in its increased expression. These findings reveal mechanisms underlying the regulation of P450-mediated pesticide resistance and also provide a potential target for pest control.
A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes
Authors: Alic Lejla , Papac-Milicevic Nikolina , Czamara Darina , Rudnick Ramona B. , Ozsvar-Kozma Maria , Hartmann Andrea , Gurbisz Michael , Hoermann Gregor , Haslinger-Hutter Stefanie , Zipfel Peter F. , Skerka Christine , Binder Elisabeth B. , Binder Christoph J.
Published: April 2020

Significance

Dysregulation of the alternative complement pathway due to impaired binding of complement factor H (CFH) to self-ligands or altered self-ligands (e.g. malondialdehyde [MDA]-modified molecules) involved in homeostasis can promote the development of complement-related diseases, such as age-related macular degeneration (AMD). We identified, in an unbiased GWAS approach, that common genetic variants within the CFH gene family (rs1061170 and the deletion of the complement factor H-related protein 1 and 3 genes [CFHR3andCFHR1]) act as major modulators of CFH recruitment and its ability to regulate complement on MDA-epitopes. These findings demonstrate the importance of the genetic status within theCFH/CFHR3/CFHR1locus in tissue homeostasis and provide a mechanistic explanation as to why deletion ofCFHR3/CFHR1is protective in AMD development.
Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis
Authors: Shao Chenwen , Yuan Jiwen , Liu Yani , Qin Yajuan , Wang Xueao , Gu Jin , Chen Guiquan , Zhang Bing , Liu Hong-Ke , Zhao Jing , Zhu Hai-Liang , Qian Yong
Published: April 2020

Significance

Endogenous hypochlorite (HClO), the strong oxidizing and chlorinating species generated by myeloperoxidase, has been speculated to be closely associated with the development of epilepsy. However, direct imaging evidence from live brains with epileptic behaviors is rare. Herein, we have developed a two-photon fluorescence probe for the real-time tracking of endogenous HClO fluxes in vivo and ex vivo in epileptic brains. The application of this probe to construct a high-throughput screening platform would rapidly screen the potential antiepileptic agents to control overexpressing HClO. This work provides a versatile chemical tool for investigating HClO under pathological conditions of epilepsy and could be used to rapidly discover additional antiepileptic agents.
MTV proteins unveil ER- and microtubule-associated compartments in the plant vacuolar trafficking pathway
Authors: Delgadillo María Otilia , Ruano Guillermo , Zouhar Jan , Sauer Michael , Shen Jinbo , Lazarova Aleksandra , Sanmartín Maite , Lai Louis Tung Faat , Deng Cesi , Wang Pengwei , Hussey Patrick J. , Sánchez-Serrano José Juan , Jiang Liwen , Rojo Enrique
Published: April 2020

Significance

Vacuoles play crucial roles in plant growth and adaptation to the environment. However, the mechanisms responsible for transporting membranes and contents to plant vacuoles remain largely uncharacterized, and the pathways and compartments involved are not fully charted. We report on the characterization of 17 vacuolar trafficking mutants that define a set of 13 cellular factors involved in transport of soluble vacuolar proteins in
Arabidopsis thaliana
. We show that two of these factors, the GARP tethering complex subunits VPS51 and VPS54, reside in an ER- and microtubule-associated compartment (EMAC) and that VPS51 interacts with the motor domain of kinesins, revealing an unknown compartment of the vacuolar pathway and suggesting that microtubules and kinesins participate in vacuolar trafficking in plants.
The microcircuits of striatum in silico
Authors: Hjorth J. J. Johannes , Kozlov Alexander , Carannante Ilaria , Frost Nylén Johanna , Lindroos Robert , Johansson Yvonne , Tokarska Anna , Dorst Matthijs C. , Suryanarayana Shreyas M. , Silberberg Gilad , Hellgren Kotaleski Jeanette , Grillner Sten
Published: April 2020

The basal ganglia play an important role in decision making and selection of action primarily based on input from cortex, thalamus, and the dopamine system. Their main input structure, striatum, is central to this process. It consists of two types of projection neurons, together representing 95% of the neurons, and 5% of interneurons, among which are the cholinergic, fast-spiking, and low threshold-spiking subtypes. The membrane properties, soma–dendritic shape, and intrastriatal and extrastriatal synaptic interactions of these neurons are quite well described in the mouse, and therefore they can be simulated in sufficient detail to capture their intrinsic properties, as well as the connectivity. We focus on simulation at the striatal cellular/microcircuit level, in which the molecular/subcellular and systems levels meet. We present a nearly full-scale model of the mouse striatum using available data on synaptic connectivity, cellular morphology, and electrophysiological properties to create a microcircuit mimicking the real network. A striatal volume is populated with reconstructed neuronal morphologies with appropriate cell densities, and then we connect neurons together based on appositions between neurites as possible synapses and constrain them further with available connectivity data. Moreover, we simulate a subset of the striatum involving 10,000 neurons, with input from cortex, thalamus, and the dopamine system, as a proof of principle. Simulation at this biological scale should serve as an invaluable tool to understand the mode of operation of this complex structure. This platform will be updated with new data and expanded to simulate the entire striatum.
Benchmark calculations of electron impact electronic excitation of the hydrogen molecule
Authors: Meltzer T , Tennyson J , Mašín Z , Zammit M C , Scarlett L H , Fursa D V , Bray I
Published: April 2020

We present benchmark integrated and differential cross-sections for electron collisions with H2 using two different theoretical approaches, namely, the R-matrix and molecular convergent close-coupling. This is similar to comparative studies conducted on electron–atom collisions for H, He and Mg. Electron impact excitation to the

b

3

Σ

u

+

,

a

3

Σ

g

+

,

B

1

Σ

u

+

, c3Πu,

E
F

1

Σ

g

+

, C1Πu,

e

3

Σ

u

+

,

h

3

Σ

g

+

,

B

′
1

Σ

u

+

and d3Πu excited electronic states are considered. Calculations are presented in both the fixed nuclei and adiabatic nuclei approximations, where the latter is shown only for the

b

3

Σ

u

+

state. Good agreement is found for all transitions presented. Where available, we compare with existing experimental and recommended data.
Spin-polarized electron transmission through B-doped graphene nanoribbons with Fe functionalization: a first-principles study
Authors: Tsukamoto Shigeru , Caciuc Vasile , Atodiresei Nicolae , Blügel Stefan
Published: April 2020

In this study, we investigate the electron transport properties of a B-doped armchair graphene nanoribbon (AGNR) suspended between graphene electrodes based on first-principles calculations. Our calculations reveal that one of the electron transmission channels of a pristine AGNR junction is closed by the B-doping. We then proceed to explore the effect of the B-doping on the spin-polarized electron transport behavior of a Fe-functionalized AGNR junction. As a result, transmission channels for majority-spin electrons are closed and the spin polarization of the electron transmission is enhanced from 0.60 for the Fe-functionalized AGNR junction to 0.96 for the B- and Fe-codoped one. This observation implies that the codoped AGNR junction can be employed as a spin filter. In addition, we investigate the electronic nature of the transmission suppression caused by the B-doping. A detailed analysis of the scattering wave functions clarifies that a mode modulation of an incident wave arises in the B-doped AGNR part and the incident wave connects to an evanescent wave in the transmission-side electrode. For pristine and Fe-functionalized AGNR junctions, such a mode modulation is not observed and the incident wave connects to a propagating wave in the transmission-side electrode. Tuning of electron transport property by exploiting such a mode modulation is one of promising techniques for designing functionality of spintronics devices. We also discuss the general correspondence between the electron transmission spectrum and the density of states of a junction.
A new mechanism of direct coupling of laser energy to ions
Authors: Vashistha Ayushi , Mandal Devshree , Kumar Atul , Shukla Chandrasekhar , Das Amita
Published: April 2020

The well-known schemes (e.g. Brunel mechanism, resonance absorption,

J

→

×

B

→

heating etc) couple laser energy to the lighter electron species of the plasma. In this work, a fundamentally new mechanism of laser energy absorption directly to the heavier ion species has been proposed. The mechanism relies on the difference between the

E

→

×

B

→

drifts of electron and ions in the oscillating electric field of the laser and an external magnetic field to create charge density perturbations. The proposed mechanism is verified with the help of particle-in-cell (PIC) simulations using OSIRIS4.0.
A new nonlinear photoconductive terahertz radiation source based on photon-activated charge domain quenched mode*
Authors: Shi Wei , Liu Rujun , Dong Chengang , Ma Cheng
Published: April 2020

We present a high-performance terahertz (THz) radiation source based on the photon-activated charge domain (PACD) quenched mode of GaAs photoconductive antennas (GaAs PCA). The THz radiation characteristics of the GaAs PCA under different operating modes are studied. Compared with the linear mode, the intensity of THz wave radiated by the GaAs PCA can be greatly enhanced due to the avalanche multiplication effect of carriers in the PACD quenched mode. The results show that when the carrier multiplication ratio is 16.92, the peak-to-peak value of THz field radiated in the PACD quenched mode increases by as much as about 4.19 times compared to the maximum values in the linear mode.
On the metallicity gradient in the Galactic disk
Authors: Loktin Alexander , Popova Maria
Published: April 2020

The problem of the chemical composition gradient in the Galactic disk is studied based on a sample of metallicity estimates of open star clusters, using Gaia DR2-improved distance estimates. A clearly non-monotonic variation was observed in the average metallicity of clusters with increasing Galactocentric distance. One can clearly see the metallicity jump of 0.22 in [Fe/H] at a Galactocentric distance of about 9.5 kpc, which appears to be linked to the outer boundary of the thinnest and youngest component of the Galactic disk. The absence of a significant metallicity gradient in the internal (R < 9 kpc) and external (R > 10 kpc) regions of the disk demonstrates the absence of noticeable metal enrichment at times of the order of the ages corresponding to those of the disk regions under consideration. Observational data show that the disk experiences noticeable metal enrichment only during the starburst epochs. No significant dependence was identified between the average metallicity and the age of the clusters.
Quantification of ferritin-bound iron in murine samples for Alzheimer’s disease studies using species-specific isotope dilution mass spectrometry
Authors: Tchaikovsky A , Schoeberl A , Schueffl H , Raab A , Emin S , Slany A , Heffeter P , Koellensperger G , Swart C
Published: April 2020

We have investigated species-specific isotope dilution mass spectrometry (IDMS) for the quantification of ferritin-bound iron in murine serum and brain. Therefore, fresh samples were analyzed using size exclusion chromatography inductively coupled plasma mass spectrometry (SEC-ICP-MS). Isotopically labeled (57Fe)ferritin was used as calibrant for the quantification of ferritin-bound iron in murine samples. Assessment of the iron load of serum ferritin was impaired by concomitant iron-containing proteins of similar size and shape, which could not be separated by SEC nor centrifugal ultra-filtration. In contrast, ferritin was the main iron-containing protein in cytosolic extracts of murine brain, which showed a total ferritin-bound iron content of (1.05 ± 0.12) µg g−1 (n= 10; U, k= 2). The relative expanded uncertainty achieved for a mass fraction of ca. 1 µg g−1 ferritin-bound iron was 11% (U
rel, k = 2). The relative expanded uncertainty of the iron mass fraction of the (57Fe)ferritin spike was 5.7% and represented the major contributing factor to the overall uncertainty. Statistical tests suggested no significant difference in ferritin-bound iron content between mouse brain hemispheres. The presented analytical tool provides low limits of quantification (2.2 ng g−1) and uncertainties (11%, U
rel, k = 2), thus enables the quantification of ferritin-bound iron in murine brain extracts with high sensitivity and accuracy. Furthermore, this analytical workflow assures comparability of measurement results across research laboratories. This provides the basis for investigation of the iron loading of ferritin in brain tissue of healthy and Alzheimer’s disease mouse models, which may help answering the question if iron regulation is impaired in Alzheimer’s disease.
Indigenous mental health in a changing climate: a systematic scoping review of the global literature
Authors: Middleton Jacqueline , Cunsolo Ashlee , Jones-Bitton Andria , Wright Carlee J , Harper Sherilee L
Published: April 2020

Indigenous Peoples globally are among those who are most acutely experiencing the mental health impacts of climate change; however, little is known about the ways in which Indigenous Peoples globally experience climate-sensitive mental health impacts and outcomes, and how these experiences may vary depending on local socio-cultural contexts, geographical location, and regional variations in climate change. Thus, the goal of this study was to examine the extent, range, and nature of published research investigating the ways in which global Indigenous mental health is impacted by meteorological, seasonal, and climatic changes. Following a systematic scoping review protocol, three electronic databases were searched. To be included, articles had to be empirical research published since 2007 (i.e. since the Intergovernmental Panel on Climate Change’s Fourth Assessment Report); explicitly discuss Indigenous Peoples and describe factors related to climatic variables and mental health. Descriptive data from relevant articles were extracted, and the articles were thematically analyzed. Fifty articles were included for full review. Most primary research articles described research in Canada (38%), Australia (24%), and the United States of America (10%), with the number of articles increasing over time. Mental health outcomes such as strong emotional responses, suicide, depression, and anxiety were linked to changes in meteorological factors, seasonality, and exposure to both acute and chronic weather events. The literature also reported on the ways in which the emotional and psychological impacts of climate were connected to changing place attachment, disrupted cultural continuity, altered food security and systems, forced human mobility, and intangible loss and damages. This review highlights global considerations for Indigenous mental health in relation to climate change, which can support Indigenous-driven initiatives and decision-making to enhance mental wellness in a changing climate.
Why do some consumers not charge their plug-in hybrid vehicles? Evidence from Californian plug-in hybrid owners
Authors: Chakraborty Debapriya , Hardman Scott , Tal Gil
Published: April 2020

The environmental benefits of plug-in hybrid electric vehicles (PHEVs) are closely related to the driving and charging behavior of vehicle owners. It is often wrongly assumed that PHEV drivers plug-in once per day. Using data from drivers of the vehicles we show this is not the case and that some drivers rarely charge their PHEV. If the vehicle is not plugged-in regularly, the vehicle will drive fewer electric miles and more gasoline miles, thereby losing out on potential emission savings. Analyzing 30-day charging behavior of 5418 PHEV owners using a logistic regression model, we explore the factors that influence driver’s decisions to not charge their vehicle. Several factors play a role in drivers’ decision to plug-in their PHEV or not, including vehicle characteristics and the availability and cost of charging at various locations. Higher home electricity prices, lower electric driving range, lower electric motor power to vehicle weight ratios, lower potential cost savings from charging, and living in an apartment or condo, among other factors are related to not plugging in a PHEV. The findings have important implications in terms of future policy and vehicle design including which PHEVs policymakers should incentivize and what measures can encourage PHEV owners to plug-in their vehicles to help realize the environmental benefits of the technology.
Time development of conformal field theories associated with L
1 and L
−1 operators
Authors: Tada Tsukasa
Published: April 2020

In this study, we examined consequences of unconventional time development of two-dimensional conformal field theory induced by the L
1 and L
−1 operators, employing the formalism previously developed in a study of sine-square deformation. We discovered that the retainment of the Virasoro algebra requires the presence of a cut-off near the fixed points. The introduction of a scale by the cut-off makes it possible to recapture the formula for entanglement entropy in a natural and straightforward manner.
Comparative Analysis the Addition of Natural and Artificial Fibres in Concrete
Authors: Oktarina Devi , Fadilasari Dewi , Juansyah Yan
Published: April 2020

Concrete structurally has a fairly large compressive strength, but has a lack of tensile strength and is brittle. This weakness can be corrected by adding natural or artificial fibres to the concrete mix evenly with a random orientation. The purpose of this study was to investigate about the effect of adding natural fibres and artificial fibres on compressive strength and tensile strength of concrete. Test specimens used are cylindrical concrete measuring 150 mm x 300 mm with natural fibres from bamboo Betung and artificial fibres from local Bendrat wire. The variation of the percentage value of the fibre fraction volume is 0%, 0.2%, 0.4%, and 0.6% and the test is carried out when the concrete is 28 days old. The results showed that the addition of natural fibres and artificial fibres to the concrete mix can increase the compressive strength and tensile strength of normal concrete at a fraction volume of 0.4%. Increased compressive strength of normal concrete is 24.31% for bamboo Betung fibre and 20.81% for Bendrat wire fibre. Whereas the increased in tensile strength of normal concrete for Betung bamboo fibre increased by 77.12% and for Bendrat wire fibre increased by 3.24%.
Factors Influencing The Greenhouse Gas Emission Disclosure on Manufacturing Firms in Indonesia
Authors: Listyaningsih Erna , Natalina
Published: April 2020

Greenhouse gas (GHG) emission disclosure study is interesting to be investigated in recent years. Nevertheless, the results are still varying. This research investigated the influence of firm size, Return on Asset (ROA), leverage and environmental performance on GHG emission disclosures of listed manufacturing firms of Indonesia Stocks Exchange (IDX). Multiple regression methodology employed in this study. Sample used was 36 firms that consisted of manufacturing companies in the ranking of PROPER and IDX during 2015-2017. It was found that firm size and environmental performance had an effect on the GHG emission disclosure while ROA and leverage did not have effect. Furthermore, large companies tend to carry out information on GHG emissions disclosures voluntarily than the small one. It indicates that the ranking of PROPER motivated large firms to give information of GHG emission. This finding supported the previous studies in which firm size influenced the GHG emission disclosure.
Development of a Household Solar Power Plant: System Using Solar Panels
Authors: Suyanto M , Rusianto T , Subandi
Published: April 2020

The purpose of this study was to find a model system of power generation by using solar-cells for house. The research was a realization of concern in overcoming the electricity energy crisis. Solar panels, inverters, batteries, and solar charge controllers were used to support on this study. Polycrystalline solar panels with 4 × 50Wp power were chosen to generate energy. The output voltage ranges from 14.8 to 17.5 V DC (direct current) per panel with a capacity of 2 × 70 Ah. Battery capacity of 24 volts was connected in series with an inverter of 1000 watts. The result of the study showed the voltage output of the solar panels was at maximum average of 30.2 V. The distribution of batteries charging used a solar charger controller at a voltage of 24.5 volt DC. The measurement of voltage resulted at the inverter output from 24 volt DC to converse of 220 volt AC (alternating current) without load. Voltage conditions as outputs of solar panels reach maximum voltage during the day from 10:00 am to 1:00 pm Western Indonesia Time (WIB) and it begin down until 6:00 pm. The design greatly influenced the performance of solar power plants.
Feasibility Study of Micro Hydropower Plants in High-Rise Buildings in Indonesia By Utilizing A Working Scheme for AC Condenser Water Pumps (Ventilation & Air Conditioning System)
Authors: Firma Purbantoro , Siregar Marsul
Published: April 2020

In Indonesia the number of high-rise buildings above 150 m tends to increase, according to CTBUH (Council on tall building and urban habitat) in 2018 there are 85 buildings and those that are under construction are 26 buildings, Super tall buildings with a height above 300 meters are 4 buildings and proposed mega tall building with a height of more than 600 meters is 1 building. All these buildings have very large electrical loads. The percentage of electricity consumption in the building that is the object of research is 30-50% coming from the Ventilation & Air Condition (VAC) system, 20% - 30% lighting systems, 10% computers and the rest from other utilities. Several papers and journals discussing the simulation or feasibility study of micro-hydropower plants in high-rise buildings have not yet been discussed how to utilized kinetic energy from the working scheme of the water condenser pump in the VAC system. in general, the existing papers discuss how to utilized gravity potential energy through the working scheme of the building’s clean water tank which is on the roof (rooftop) when distributing water which is not optimal because of the flow of water from the clean water system is not continuous or steady-state. Research Object by taking a case study of a high-rise building in Jakarta with a height of 157 meters. The data was taken from the report on utility use for the 2018 period in the building. From the simulation, the potential of water flow rate (Q) is 0.499 m3 / sec and the electrical power that can be generated (P) is 733.83 kW and this is a Micro-hydro Power Generation category. Economic analysis for building energy savings of Rp. 541,765,714.29 / month and finally roughly Return on Investment (ROI) can be achieved in 3 years and 6 months.
The Ratio Resin Polyester Composite Basal The To Testing Pull
Authors: Tumpal Ojahan R , Ansyori Anang , Alimuddin Zulfikar
Published: April 2020

Dropsy of the pollen and polyester resin constitutes the materials that can make material composite after the mixing of both, namely basal dust as filler and as a matrix. Polyester resin this research do the ratio of basal 40, mesh size of pollen 60, mesh and 150 mesh against 15 %, polyester resin 20 %, and 25 %.To get matrial, composite printed according to standard ASTM-D638 type V as for the purpose of this research is to obtain information regarding the ratio of polyester resin with basal powder against tensile strength and scored a maximum and minimum as well as determine the outcome of tensile strength of the ratio of basal powder 40, mesh 60, mesh150 mesh with resin polyester 15 %, 20 %, 25 % and a mixture of a catalyst 1/10, 1/20, 1/30 of the results of the analysis uses the method taguchi kompsisi resin polyester optimal there are on 25 % and the 60 mesh and catalyst 1/30 gr.The results of minimum found in composite basal the 150 mesh with force 60 Kgf with fariasi resin 15 % and catalyst 1/10, while a maximum score found in composite basal the 60 mesh with fariasi resin 25 % and catalyst 1/30 with force of 135 Kgf. Of the result analysis using a method of taguchi kompsisi polyester resin levels found in 25%, while basal 60 mesh, powder and a catalyst 1/30 gr.
Quality Service Analysis at Pusat Pelayanan Pendidikan Terpadu (P3T) Universitas Malahayati Using Fuzzy and Service Quality Method
Authors: Wardana M W , Sidiq A , Wibowo H , Pangestu Y
Published: April 2020

Each institution must try to provide the best service for costumers, but the level of customer satisfaction with a service is different. Every customer always expects to get the optimal service they want. This study aims to determine the level of service quality (Servqual) in the Quality Analysis of Pusat Pelayanan Pendidikan Terpadu (P3T) with Fuzzy Methods and Quality Services at Universitas Malahayati based on five dimensions of Tangible, Reliability, Responsiveness, Assurance and Empathy. This research was conducted by distributing questionnaires to P3T service users and then testing the validity and reliability. The method used is the fuzzy method followed by the calculation of the gap. Respondents in this study were 100 mixed students of various study programs at Universitas Malahayati with an error rate of 10%. The results of the calculation showed that the service performance provided by P3T was almost all the attributes whose performance must be improved. By improving the attributes that have high inequality values, it is expected to improve the quality of the P3T service so that it can increase the trust of service providers to customers.
The Effectiveness of Corncob Activated Carbon in Reducing Chromium (Cr), Cadmium (Cd), Copper (Cu), and Zinc (Zn) Levels in Electroplating Wastewater
Authors: Ergantara R.I , Panisean N. , Dewi S. N , Sidiq I
Published: April 2020

The heavy metal from industrial electroplating wastewater can directly affect the environment even at very low concentration. The application of agricultural waste as low-cost adsorbents of removing heavy metal has been developed. This study aimed to determine the effectiveness of corncob activated carbon in reducing levels of Cu, Zn, Cr, and Cd in electroplating wastewater. The adsorbent from corncob dried in the sun, carbonized for 24 hours until carbon was formed. Then it was activated by HCl 9% for 24 hours, dried, crushed, and sieved with 80 mesh size sifter. The variation of the discharge are 15ml/min, 20 ml/min, and 25ml/min, the sample was taken at 0, 5, 10, 15, and 20 minutes. The results show that the highest reduction of Cr, Cd, Cu, and Zn occurred at 15 ml/minute discharge in the 5th minute with the total removal efficiency of Cr, Cd, Cu, and Zn were 25.75%, 43.42%, 50.39%, and 53.97%. Furthermore, it indicates that corncob activated carbon was found to be most effective in reducing of Zinc (Zn).
Influence of Temperature on The Yield and Characteristic of Bio Oil from Pyrolysis of Pine Sap
Authors: Baskoro Wim Widyo , Arifin Muhammad Zainal , Anis Samsudin
Published: April 2020

The purpose of this work is to investigate the influence of temperature on the yield and characteristic of bio oil produced from pyrolysis of pine sap. The batch pyrolysis processes were conducted in an electric furnace at various temperature ranging from 350°C to 450°C. In each experiment, about 1 kg sample was pyrolyzed to obtain bio oil under inert environment by flowing nitrogen gas at 0.4 lpm. The produced bio oils were then characterized to obtain their physical and chemical properties. The result exhibited that the bio oil yield increased as the pyrolysis temperature increases. The highest yield of bio oil of 23.03 wt.% was achieved at 450°C. At this condition, the bio oil had specific gravity of 0.998, degree of acidity (pH) of 3.83, heating value of 5673.05 cal/g, and viscosity of 1.97 mm2/s. The bio oil composed of hydrocarbon component with carbon chain of C10–C21. It was found that more than 70 wt.% bio oil occupied by hydrocarbon fuel of >C14 that could be categorized as biodiesel fuel. In the meantime, bio oil produced at 350°C composed of hydrocarbon with carbon chain of C10 only that could be utilized as gasoline fuel.
Estimating Rotational FRFs of a Complex Structure Using FE Model Updating, Mode Expansion and FRF Synthesis Method
Authors: Iskandar Mirza Wii Wan , Rani Mn Abdul , Yunus Ma , Febrina Rina , Sani Msm
Published: April 2020

Estimating rotational frequency response functions (FRFs) from experimental data is very challenging, and the estimation often leads to poor FRFs due to the presence of spurious resonance peaks. In practice, special equipment is essentially required in the measurement process, unless the rotational FRFs are synthesised using measured modal data. This paper presents an alternative approach for estimating the rotational FRFs of a geometrically complex structure by using finite element modal updating, mode expansion and the FRF synthesis method. The applicability and accuracy of the proposed approach are demonstrated on a car front-end module A simplified finite element (SFE) model of the test structure is introduced and the SFE model is then updated based on the measured modal model obtained from experimental modal analysis. The mode shapes of the updated SFE model are expanded to the test model to obtain the entire translational and rotational modal vector. The rotational FRFs of the expended experimental model is derived via the FRF synthesis method. The derived translational FRF is compared with the measured counterparts for validation purposes. It was found that the derived translational and measured FRF are in a perfect match, and the derived rotational FRF has successfully estimated all the resonance peaks within the frequency of interest. The findings from this work may be useful in improving the accuracy of the experimental rotational FRFs, which are crucial for particular structural dynamics analysis.
Surface passivation of AZOY/n-Si interface of heterojunction solar cells with NH4F solution treatment
Authors: Wang Na-Fu , Tsai Yu-Zen , Cheng Yu-Song
Published: April 2020

This study reports the fabrication of n-type aluminum- and yttrium-codoped zinc oxide (AZOY) on n-Si (AZOY/n-Si) heterojunction solar cells (HJSCs) by using RF magnetron sputtering at various working pressure. AZOY thin films deposited on glass and n-Si substrates at various working pressure were evaluated for optoelectrical properties and performance. At a working pressure of 3 mTorr, the AZOY films showed the lowest resistivity of 8.11 × 10–3 Ωcm and visible transmittance (400–800 nm) of 84.64%, and AZOY/n-Si HJSCs achieved a high conversion efficiency of 11.83% (Voc: 498 mV, Jsc: 35.89 mAcm−2, and FF: 0.662). Repeating the optimal working pressure, the n-Si substrate was immersed in ammonium fluoride (NH4F) solution to improve the AZOY/n-Si interface state. The fluorine atom had the strongest electron negativity for effective passivation of the silicon dangling bond, and the device’s performance was able to further increase conversion efficiency to 12.64% (Voc: 523mV, Jsc: 36.79 mAcm−2, and FF: 0.657). Moreover, NH4F solution treatment of the silicon surface can increase the thinness of the SiOx layer from 1.27 to 0.79 nm and reduce the interface state density from 8.59 × 1011 to 1.13 × 1011 cm2.
Ferromagnetism in undoped ZnO grown by pulsed laser deposition
Authors: Azeem Waqar , Luo Cai-Qin , Xu Chi , Zhou Shengqiang , Wagner A , Butterling M , Younas Muhammad , Ling Francis Chi-Chung
Published: April 2020

Undoped ZnO films grown on sapphire by pulsed laser deposition are magnetic at room temperature. A comprehensive study involving x-ray diffraction, positron annihilation spectroscopy, and superconducting quantum Interference device-vibrating sample magnetometer is performed to study the origin of the observed magnetization. Correlations between the saturation magnetization, VZn−2VO concentration and surface to volume ratio of the grain found experimentally show that the magnetization is associated with the vacancy cluster and probably VZn−2VO residing on the grain surface.
Synthesis of Pb(Zr0.35−xMnxTi0.65)O3, x = 0.00, 0.02, 0.06, 0.10 ceramics and their structural, dielectric characteristics
Authors: Tiwari Balgovind , Babu T , Choudhary R N P
Published: April 2020

The samples of stoichiometry Pb(Zr0.35−x
Mn
x
Ti0.65)O3, x = 0.00, 0.02, 0.06, 0.10 (PZMT) were synthesized by solid state reaction route. For the first time, 35/65 lead zirconate titanate ceramics were modified by manganese (Mn) by replacing zirconium. X-ray diffraction (XRD) study has confirmed the formation of tetragonal phase in samples and no structural change has been observed due to Mn doping. Results of scanning electron microscopy (SEM) showed polycrystalline nature through shape, size and grain distribution in microstructures of all samples. At room temperature, the samples have shown identical nature in variation of dielectric constant (ϵ

r
) and tangent loss (tanδ) with frequency. At 50 kHz frequency, the value of maximum dielectric constant (ϵ
max) has been changed from 5440 to 12 562 due to Mn. With increase in doping amount of Mn, the values of Curie temperature (T

c
) have been decreased from 435 to 373 °C.

Tan
δ

of samples is decreased with increase in the dopant concentration. The diffusivity of PZT has increased with 2% of Mn doping. But further increase in the Mn concentration has decreased the diffusiveness of the samples.
2. The Sun’s life-cycle
Authors: Judge Philip
Published: April 2020

‘The Sun’s life-cycle’ describes the birth of the Sun out of the debris of stars which exploded early in the life of the Milky Way. When stars form, they employ a disc structure, with matter spinning around the centre of mass like a carousel, aided by magnetic fields. At four and a half million years old, the Sun, like most stars in the Universe, is on the main sequence stage of its life. In this stage, nuclear fusion reactions in its core fuse hydrogen into helium. Both observations and theory infer that the Sun spun faster in the past and was both hotter and less luminous.
4. The dynamic corona
Authors: Judge Philip
Published: April 2020

‘The dynamic corona’ introduces the layer of the Sun first seen by humans during eclipses. Initially, scientists were troubled by the idea that an outer layer of the Sun was hotter than its core. The corona continuously emits hot plasma and acts as a valve for a build-up of magnetic energy (helicity) that would otherwise stifle cyclic behaviour, such as sunspots. Originally predicted in the 1950s by a scientist using a pressure cooker as a model, the solar wind was identified and sampled shortly afterwards by American and Russian space missions. In the catalogue of known solar phenomena, flares preceded CMEs (coronal mass ejections), but they seem to be linked.
International Relations: A Very Short Introduction
Authors: Reus-Smit Christian
Published: April 2020

International relations affects the security, economic fortunes, rights and freedoms, and environmental well-being of all of us. The recent transformation from a world of empires to today’s sovereign states, meshed in a complex array of international institutions, has far-reaching consequences. International Relations: A Very Short Introduction untangles this constantly evolving subject, exploring the changing ways that political authority has been organized and maintained globally. Throughout, Christian Reus-Smit provides the theoretical and historical tools to understand the origins and dynamics of contemporary international relations, and sheds new light on the nature of global political change.
2. The global organization of political authority
Authors: Reus-Smit Christian
Published: April 2020

‘The global organization of political authority’ examines such organization more closely, and provides a brief overview of some of the most prominent historical forms: heteronomy (think of feudal Europe), empire (from the Moghul to the British), and sovereignty (in today’s global system). It first emphasizes the nature and importance of institutions, understood broadly as formal or informal systems of rules, norms, and practices as they play a crucial role in organizing political authority. Second, it places today’s global system of sovereign states in a broader conceptual and historical framework, encouraging readers to see it as one crucially important, yet utterly unique, way of ordering social and political life.
3. Theory is your friend
Authors: Reus-Smit Christian
Published: April 2020

The global organization of political authority remains complex and shifting. We can ask any number of fascinating questions about this organization, from how and why it changes over time to its relationship with organized violence and inequalities of gender, race, or ethnicity. But how are we to answer them? One response would be to begin by looking at the relevant facts; but what facts should be included and excluded? ‘Theory is your friend’ argues that theory is essential to these tasks. It surveys six prominent theoretical perspectives on international relations: realism, liberalism, constructivism, the English School, feminism, and post-colonialism. All are centrally concerned with the global organization of political authority.
Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytologic Evaluation of Intraductal Papillary Mucinous Neoplasm and Mucinous Cystic Neoplasms of Pancreas
Authors: Gilani Syed M , Adeniran Adebowale J , Cai Guoping
Published: April 2020

Objectives

To evaluate the role of endoscopic ultrasound-guided fine needle aspiration cytology in identifying mucinous cystic lesions (MCLs) in histologically proven cases of intraductal papillary mucinous neoplasm (IPMN) or mucinous cystic neoplasm (MCN) and risk of malignancy associated with each cytologic category based on the Papanicolaou Society of Cytopathology (PSC) guidelines.

Methods

All resected cases with histologic diagnosis of IPMN or MCN at our institution from January 1, 2004, to August 31, 2019, with associated cytology were included. Available cytology slides of nondiagnostic (ND), negative/benign (BN), and atypical cytology (AC) cases were reviewed and reclassified based on the PSC guidelines.

Results

A total of 120 cases were identified, including 57 IPMNs with low-grade or moderate dysplasia (LGD/MD) and high-grade dysplasia (HGD), 34 MCNs with LGD/MD or HGD, and 29 IPMNs with invasive malignancy. After cytology slide review and reclassification, we observed that ND and BN cases were paucicellular and lacked ancillary testing (carcinoembryonic antigen levels or KRAS mutation analysis). The risk-of-malignancy rates were 33% for ND, 11% for BN, 28.5% for AC, 17% for MCL, and 100% for suspicious/positive cytologic diagnosis.

Conclusions

A multidisciplinary approach including combined use of cytology and ancillary testing is helpful in establishing a diagnosis of MCL and identifying associated malignancy.
Few Losses to Follow-up in a Sub-Saharan African Cancer Cohort via Active Mobile Health Follow-up
Authors: Foerster Milena , Anele Angelica , Adisa Charles , Galukande Moses , Parham Groesbeck , Zietsman Annelle , Oyamienlen Christopher Sule , Iwuoha Kingsley Chukwunyere , Ezeigbo Esther , Bakengesa Evelyn , Kaggwa Agnes , Naamala Allen , Nteziryayo Anne , Nakazibwe Teopista , Pinder Leeya F , Walubita Emily , Pontac Johanna , Anderson Benjamin O , McKenzie Fiona , Schüz Joachim , dos Santos Silva Isabel , McCormack Valerie
Published: April 2020

Accurate survival estimates are needed for guiding cancer control efforts in sub-Saharan Africa, but previous studies have been hampered by unknown biases due to excessive loss to follow-up (LTFU). In the African Breast Cancer—Disparities in Outcomes Study, a prospective breast cancer cohort study, we implemented active mobile health follow-up, telephoning each woman or her next-of-kin (NOK) trimonthly on her mobile phone to update information on her vital status. Dates of every contact with women/NOK were analyzed from diagnosis in 2014–2017 to the earliest of September 1, 2018, death, or 3 years postdiagnosis. The cumulative incidence of being LTFU was calculated considering deaths as competing events. In all, 1,490 women were followed for a median of 24.2 (interquartile range (IQR), 14.2–34.5) months, corresponding to 8,529 successful contacts (77% of total contacts) with the women/NOK. Median time between successful contacts was 3.0 (IQR, 3.0–3.7) months. In all, 71 women (5.3%) were LTFU at 3 years: 0.8% in Nigeria, 2.2% in Namibia, and 5.6% in Uganda. Because of temporary discontinuity of active follow-up, 20.3% of women were LTFU after 2 years in Zambia. The median time to study notification of a death was 9.1 (IQR, 3.9–14.0) weeks. Although the present study was not a randomized controlled trial, in this cancer cohort with active mobile health follow-up, LTFU was much lower than in previous studies and enabled estimation of up-to-date and reliable cancer survival.