bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemberdayaan Kelompok Wanita Tani Sri Rejeki pada Pengolahan Sediaan Umbi Bawang Dayak (Eleutherine bulbosa Urb.)
Authors: Muthia Rahmi , Akbar Depy Oktapian , Putri Aristha Novyra , Sandi Dita Ayulia Dwi , Vebruati Vebruati , Kunmariana Revi
Published: January 2023

One form of traditional health development is the development of medicinal plants. Not many community groups are currently aware of applied technology in terms of postharvest processed into simplicia (medicine raw materials) or other processed preparations. Sri Rejeki Farmer Women’s Group (KWT Sri Rejeki) in the Landasan Ulin Village, Liang Anggang District, is a group of women who cultivate vegetables and plants that can be used as medicinal plants, one of which is Dayak onion (Eleutherine bulbosa Urb). The activity carried out by KWT Sri Rejeki had only been in the form of planted plants, which were then sold in fresh form. This community dedication aimed to educate the public, especially KWT Sri Rejeki, regarding the efficacy of Dayak onion bulb plants. It optimized the use of cultivation and processed plants into traditional medicinal preparations with economic value. The method used was site review and plant data collection from KWT Sri Rejeki, education on the efficacy of Dayak onion bulbs, training on processed dayak onion bulbs into simplicia, and training on processing dayak onion bulbs into dye preparations. The data collection results were Dayak onions selected as a typical Kalimantan plant to be developed, with the efficacy as an immunomodulator. Dayak onion bulbs that will be designed were processed into simplicia which were then made into dye preparations and packaged. The processing of simplicia and preparations for dipping Dayak onion bulbs can be done independently by the members of the KWT Sri Rejeki.
Pemberdayaan Remaja Guna Meningkatkan Minat Literasi Kesehatan Mental di Era Digital
Authors: Isni Khoiriyah , Laila Farikhah Nur
Published: January 2023

WHO data in 2017 shows that there are still high cases of depression in Indonesia among children, adolescents, and early adults. This is due to the limited knowledge of adolescents related to mental health literacy. This training aim is to increase adolescent expertise about mental health literacy to help adolescents. The methods used in this service activity include education, training, case studies, simulations, and role-playing. Activities are carried out in compliance with health protocols. The training activity involved 25 youth of the Warungboto Village, held for two days at the Pendopo Umbulharjo District, Yogyakarta. The results obtained from this dedication are differences in adolescents' knowledge before and after giving education about mental health literacy. Participants can analyze mental health problems and provide solutions to these problems. The importance of mental health literacy helps adolescents recognize the issues in themselves to seek help/assistance appropriately.
Implementasi Quranic Bibliotherapy untuk Menurunkan Kecemasan pada Ibu Hamil
Authors: Fatmawati Ariani , Aisyah Popy Siti , Dewi Inggriane Puspita , Febriyani Resha Eka
Published: January 2023

Health care for expectant women primarily focuses on physical health, particularly in Independent Midwife Practice (PMB) in Bandung. Currently, only blood pressure checks, weight assessments, the administration of iron supplements, laboratory testing, tetanus vaccinations, and assessments of the fetus's position and heart rate are performed. Meanwhile, stress or anxiety is every day during pregnancy for pregnant women. This condition needs to be treated, and one method is spiritual. Using Quranic bibliotherapy as spiritual intervention, anxiety during pregnancy is reduced. Pregnant women who experienced anxiety were given anxiety questionnaires to complete, and those who did were gathered into groups and given three meetings' worth of quranic bibliotherapy through Zoom. Pregnant women who reported experiencing anxiety were subsequently collected into groups and given a three-meeting Quranic bibliotherapy intervention through Zoom Meetings and in person. The activity began with the distribution of anxiety questionnaires to pregnant women. The activity's results revealed that there had been a change in the participants' levels of anxiety, which had previously ranged from mild anxiety at 40% to moderate anxiety at 50%, severe anxiety at 10%, mild anxiety at 60%, and moderate anxiety at 40%. To use quranic bibliotherapy interventions on anxious pregnant women, midwives must have the necessary training.
Menumbuhkan Bisnis Digital dengan “Grow with Google” Implementasi Teknologi Era Pandemi Covid-19
Authors: Novika Fanny , Addini Fida Fathiyah
Published: January 2023

The Covid-19 pandemic that occurred in Indonesia had an impact on various sectors. The decline in activity and changes to digital systems due to the pandemic are the main factors causing the impact on society. One of the sectors affected is the business sector. Not a few businesses were forced to close because they were unable to deal with changes to the digital system. Google as the largest technology company has a product in the form of training for business people for free. Google also offers the appearance of a business profile in search results or maps. This activity aims to provide literacy and assist business people to improve their competence in using Google products. Literacy is carried out as the initial foundation for business people regarding the basics of digital marketing. Competency improvement is achieved by participating in skills training from Google and applying business profile media, maps search, and advertising media. The results of this activity indicate that the final knowledge of the participants about digital marketing is quite good and there is additional knowledge about business-related products from Google. In addition, one of the selected business owners has been assisted in successfully using business-related products from Google and advertising on Google.
Pelatihan Komunikasi Assertif (Assertive Training) Pelajar SMP IT Insan Mulia Surakarta
Authors: Argestya Ulfa Fauzia , Fadillah Galih Fajar , Hidayati Anni Nurul , Nugroho Dhanu Eko
Published: January 2023

This community service activity aims to provide an inculcation of an effective communication style, namely assertive communication at SMP IT Insan Mulia Surakarta.Online elearning causes students to have difficulty communicating, especially students of SMP IT Insan Mulia Surakarta. Some students still do not dare to refuse friends to play on the sidelines of study group activities or assignments, do not dare to ask the teacher during the learning process, are passive when they have arguments or ideas in organizational forums at school. If this is left without any preventive measures, it will have an impact on the development of student communication at SMP IT Insan Mulia Surakarta. The purpose of this activity is to provides training on effective communication styles, namely assertive communication. The method used in the delivery of communication styles is to use classical and group methods. This training was held for two days. On the first day of classical training in the form of materials and assignments, while the second day in small groups, namely the practice of assertive communication. The data collection instrument used an open questionnaire and observation. Based on the analysis of the instrument students showed changes in communication, namely students to convey their ideas or openly tell the conditions they are experiencing.
Pemberdayaan UMKM melalui Inovasi Marketing berbasis Teknologi Informasi
Authors: Himarosa Rela Adi , Krisdiyanto Krisdiyanto , Wardana Primadian Adhi , Maulana Nur Rachman , Sofyantoro Fajar
Published: January 2023

Pondok Pesantren Asy-Syifa' Muhammadiyah (PPAM) in Yogyakarta established several Micro, Small and Medium Enterprises (MSMEs) including production units of tempeh, mineral water, coffee, and donut. The main obstacle experienced by the MSMEs is the traditional marketing system which limits the sales of products. The current program aimed to assist the adoption of information technology, especially in marketing techniques using social media and e-commerce. The activities included discussions with MSMEs owners, socialization of marketing techniques, creating social media accounts, making of product catalogs, and evaluation. In general, all the activities could be carried out as targeted. After participating in this program, the MSME owners at PPAM are able to use social media and e-commerce to increase product marketing and sales.
Pelatihan Pembuatan Pupuk dan Pestisida Organik bagi Petani Cabai di Desa Tajau Landung Kabupaten Banjar
Authors: Mariana Mariana , Liestiany Elly , Budi Ismed Setya , Samharinto Samharinto , Pramudi Muhammad Indar , Fitriyanti Dewi
Published: January 2023

Chili is one of the vegetable commodities that have excellent and promising business opportunities in Tajau Landung Village. In this village there are 16 farmer groups and 75% of them grow chilies, both large chilies and cayenne peppers. Pesticides and chemical fertilizers are the main production factors in chili farming. Prices and access to subsidized pesticides and chemical fertilizers are a constraint for farmers, and their residues have a negative impact on consumers and the environment. This activity aims to provide training to farmers in Tajau Landung Village to produce organic fertilizers and pesticides. The activity began with counseling about Chili Pests and Diseases and how to control them organically, as well as pretest and posttest using a questionnaire. The next activity was training on making bokasi fertilizer enriched with Trikoberas, and PGPR (Plant Growth Promoting Rhizobacteria). Based on the results of the evaluation, it was concluded that there was an increase in participants' understanding of chili pests and diseases and their control before and after being given counseling. %). Participants already have skills in making organic bokasi fertilizer from water hyacinth and kiyambang weeds, PGPR, and Trikoberas added to bokasi fertilizer to become Trikokompos, and showed very good acceptability assessment results.
Antioxidant and Antimicrobial Agents from Avocado (Persea americana) Seed Extract Encapsulated in Gum Arabic through Spray Drying Method
Authors: Kautsar Duhaul Biqal , Rois Mahardika F. , Faizah Nurul , Widiyastuti Widiyastuti , Nurtono Tantular , Setyawan Heru
Published: January 2023

In this work, the objective is to utilize avocado seed extract as a cheap alternative source of active compounds and was successfully encapsulated using gum arabic by spray drying as an antioxidant and antimicrobial agent. First, the active compounds were extracted from avocado seed using solvent n-hexane and followed by solvent separation using rotary vacuum evaporator. Next, gum arabic as the encapsulation agent was added to avocado seed extract to form an emulsion, then spray-dried with drying air at a temperature of 140 °C. The mass ratio of avocado seed was varied at extract: gum arabic of 5:5, 5:10, 5:15, and 5:20. Then, the particle morphology, yield, moisture content, encapsulation efficiency, loading capacity, chemical groups, antioxidant activity, and antibacterial ability were analyzed to investigate the performance of the encapsulation particles. Among the ranges studied, the extract–gum arabic with a mass ratio of 5:10 exhibited the best properties of yield powder, loading capacity, and encapsulation efficiency at 49.78%, 3.43%, and 7.33%, respectively. The encapsulated particles have smooth surface, crackless, lower indentation, and a single-core encapsulation structure with an average diameter of 4.60 μm. Besides, the stability of antioxidant activity decreased by 2.36%, from 94.82% to 92.46% for four weeks of storage. They also performed antimicrobial activity against E. coli and S. aureus, which were maintained after seven days. Meanwhile for avocado seed extract only, the unencapsulated stability of antioxidant activity has continually decrease from 91.58% to 84.05% and performed no antimicrobial activity against E. coli after seven days.
Transformation of Condolence in the Digital Age: A Case Study on Turkish Culture
Authors: Serttaş Aybike , Sarıkaya Tugay
Published: January 2023

The purpose of this article is to demonstrate the practice of condolence of digital immigrants in Turkey. Although digital media technologies expand communication opportunities and networks, they also cause changes in social relations between people. Versatile communication has become possible thanks to digital media technologies as opposed to non-interactive or unilateral communication of conventional media. Nowadays, it is possible to send a message to dozens of people with just one click. As such, new attitudes and behaviors are observed in the society along with the developing possibilities of digital media. The hypothesis of the study is "digital immigrants that use social media platforms in Turkey has experienced a change in the practice of condolences." In this regard, the emphasis put on the changes in condolence practices that occur across Turkey is discussed along with new Internet technologies. We conducted interviews with 15 participants among the ages of 52 and 69 between April and June 2020. According to the findings, we see that many of the participants adopt traditional condolence practices, but they do not devalue the condolence practices that occur on social media. We observed that digital condolence practices have started to coexist with traditional condolence practices, but this change should not be perceived as the traditional one is beginning to be erased or disappeared. 
Los eventos corporativos y la digitalización de los sentidos en el metaverso: estudio de caso de la marca de moda Gucci
Authors: Salanqueda i Mayor Mireia , Puntí Brun Mónica
Published: January 2023

Los metaversos se postulan como uno de los escenarios más próximos y como realidades inmersivas que podrán abrir nuevas posibilidades a medida que se avance en su desarrollo. El presente estudio pretende analizar si se pueden, y de qué forma, crear en el metaverso eventos corporativos utilizando tecnologías de digitalización de los sentidos y técnicas del marketing experiencial y sensorial. En consecuencia, en esta investigación se ha comprobado que el metaverso permite la fusión de las emociones y los sentidos con la tecnología, lo que supone una oportunidad para ofrecer experiencias distintas a las del mundo físico en un contexto en el que es esencial cautivar al público joven y en el que los eventos y las comunicaciones de las empresas deben ir un paso más allá. A través de una entrevista, un análisis de contenido y el estudio de caso de la marca Gucci, se ha corroborado que la inserción en el metaverso por parte de las marcas ya es posible. A su vez, se ha confirmado la importancia de integrar el metaverso como parte de la estrategia y como el espacio idóneo para abastecer todos los ámbitos digitales. El metaverso puede ofrecer experiencias únicas a los consumidores que buscan disfrutar de los productos y servicios de manera interactiva e inmersiva a través de los cinco sentidos. 
Una aproximación teórica a la evolución de los entornos 3D hacia la realidad extendida como medio y a los motores de juego como elementos de prototipado y configuración
Authors: Rubio-Tamayo José Luis , Carbonell-Alcocer Alejandro , Gertrudix Manuel
Published: January 2023

En los últimos años, se ha producido una evolución sin precedentes de las tecnologías de la información y la comunicación. Las tecnologías para la producción de contenidos interactivos en el ámbito de la realidad extendida no son la excepción, existiendo numerosas posibilidades a la hora de generar experiencias inmersivas y con un elevado grado de interactividad. Desde una aproximación teórica, el artículo analiza el rol de los motores de juego o game engines como herramientas de conceptualización de experiencias en el ámbito de la realidad extendida, atendiendo a sus características, y planteando una mejora de la experiencia de usuario y de las posibilidades inmediatas que ofrecen estas tecnologías. Para ello, se realiza una revisión de las aproximaciones teóricas de los autores de referencia en la investigación de motores de juegos, se compara con la evolución de las herramientas de creación 3D y sus usos, y se proyecta el impacto y la influencia que tiene en el desarrollo de contenidos en el ámbito de la realidad extendida, particularmente, la realidad virtual, y el metaverso. Las conclusiones muestran la oportunidad que representan actualmente este tipo de herramientas en la creación de contenidos digitales, y su rol indispensable en la generación de experiencias dentro de la categoría de realidad extendida.
Book Review THE METAVERSE and How It Will Revolutionize Everything, by Mathew Ball,
Authors: Gürkan Hasan
Published: January 2023

Book Review
THE METAVERSE and How It Will Revolutionize Everything, by Mathew Ball,
Liveright Publishing Corporation, 2022, 352 pages, ISBN: 978-1324092032

Dr. Hasan Gürkan
https://orcid.org/0000-0002-3805-9951
Del “Being Digital” a “El metaverso. Un viaje hacia la Tierra digital”.
Authors: Puig Borràs Núria
Published: January 2023

RESEÑA DEL LIBRO “EL METAVERSO. UN VIAJE HACIA LA TIERRA DIGITAL.”

De SANGKYUN KIM

Editorial: ANAYA. 

PÀGS 186
Integration in Undergraduate Medical Course of Bangladesh: Students’ and Teachers’ views
Authors: Islam Mohammad Rashadull , Alam Kazi Khairul , Rahman Mohammad Mohibur
Published: January 2023

This cross sectional study was conducted to evaluate the MBBS (Bachelor of Medicine and Bachelor of Surgery) course of Bangladesh on the basis of modern ‘Integrated teaching’ instead of corresponding traditional ‘Discipline-based teaching’. The study was conducted during the period of January 2021 to December 2021. Data were collected from conveniently selected eight medical colleges of Bangladesh. One self-administered semi-structured questionnaire was administered to collect data from 87 teachers and from 413 students of MBBS course. It was found that out of 4 point scale (1 to 4) the mean scores of respondents’ views regarding ‘Integrated teaching’ in the present curriculum was 1.2; on the other hand, their views regarding the future MBBBS course should adopt ‘Integrated teaching’ instead of traditional ‘Discipline based teaching’ was 3.47. The score of the respondents’ opinion regarding the different requirements were above 3.4 out of 4. Now it is best time to shift our MBBS course towards ‘Integrated teaching’ in instead of ‘Discipline-based teaching’.
Bangladesh Journal of Medical Education Vol.14(1) January 2023: 56-62
Views of Final Phase Undergraduate Medical Students’ About the Personal & Familial Factors those Influence Their Future Career
Authors: HM Habibullah , MAS Talukder , Z Naiem
Published: January 2023

Background: The understanding of the medical career decision-making process is important to aid career counseling and thus prevent wrong choices, support medical graduates in their choice and promote faster choices. An understanding of the factors which influence doctors’ career choices, and how attitudes vary among doctors who choose different specialties, is important for all those involved in the teaching and training of doctors.
Objectives: This study was done to explore views of final phase undergraduate medical students of Bangladesh about the personal & familial factors those influence their future career selection.
Methods: This descriptive type of cross sectional study was conducted on 784 students randomly selected from eight medical colleges of Bangladesh, in the period of January 2019 to December 2019 with a pre tested self-administered questionnaire.
Results: Study revealed that a total of 784 students responded, out of which 318(40.6%) males and 466(59.4%) females. Among them 726(92.6%) students wanted to do post-graduation after graduation. The leading reasons for selecting future career were personal preference 348(50.6%), self confidence 272(39.1%) and to take care of other family members 223(32.9%).
Conclusion: Study recommended that orientation and career counseling at different stages in undergraduate medical education may help students and future doctors to choose their specialty for career as per the community healthcare needs.
Bangladesh Journal of Medical Education Vol.14(1) January 2023: 63-69
Oral Complications and Their Management in Patients With Cancer During Chemo or Radiotherapy in Bangladesh
Authors: Abbasi MM Alamgir Siddique , Ali Mir Nowazesh , Islam SM Shahinul
Published: January 2023

Cancer is a very alarming disease that affects many people in every year all over the world and also in Bangladesh. Under this study a descriptive cross-sectional study was conducted to assess the knowledge on oral health status and its care before, during and after therapy. Total 145 cancer patients were selected and interviewed through a semi-structured questionnaire. Out of them 82 female and male 63 where 56 patients were treated by radiotherapy (38.62%), 72 patients were treated only by chemotherapy (49.66%) and 17 patients received both radio and chemotherapy. Here 80.69% of patients having pain during therapy while 28.96% and 11.03% before therapy. On the other hand, 61.38% patients had a change of taste after therapy whereas 8.96% had a change of taste during therapy. It was observed that the both physical and psychological well-being of oral health on quality of life which had a high effect on physical pain where 30.34% was very high, 46.21% was moderate, 20.69% a little and 2.76% not at all. In the psychological well-being study 62.76% patients felt very depressed where 37.24% fear moderate type of functional disability and 34.48% feel very lonely of remote from other people. Most patients developed sensitivity, altered taste, oral thrush, mucositis, trismus and xerostemia during and after palliative treatment. Poor knowledge (70.6%) was observed among patients in recommended quality of tooth brush, frequency of tooth brushing, duration, motion and recommended diet. Most of the patients (29.4%) were found with low quality of life. The study also concluded that patients should be provided with adequate knowledge about oral care before taking chemotherapy or radiotherapy.
J Bio-Sci. 30(1): 49-59, 2022 (June)
Growth and Reproduction of Thai Sharpunti (Barbonymus Gonionotus) In the Lentic Water Habitat of Northwest Bangladesh
Authors: Ali MR , Mondol MRM
Published: January 2023

This study evaluated the growth and reproductive activity of Thai sharpunti Barbonymus gonionotus in the L-shaped freshwater pond at Rajshahi University campus of northwest Bangladesh during January and August, 2017. Length and weight increment was recorded for the growth study and gonado-somatic index (GSI) with fecundity was estimated for the assessment of reproductive activity. During the study a significant length and weight increment was observed (p<0.05). Monthly mean total length (TL) ranged 11.76 to 22.47 cm, fork length (FL) was 10.02 to 19.12 cm, standard length (SL) was 8.87 to 16.83 cm and body weight (BW) was 19.89 to 167.81g. Both the length-length relationship (LLR) and length-weight relationship (LWR) showed a positive allometric growth pattern of the fish and the relationships were TL = 1.1759 FL - 0.035, TL = 1.338 SL - 0.0002, FL = 1.0988 SL + 0.6557 and BW = 0.0051TL 3.347. Gonadal observation showed that the fish initiated sexuality in the month of April and was fully matured in the month of May. During the study male female ratio was significantly different from the 1:1 ratio (χ2 = 3.84, p<0.05) and the overall male to female sex ratio was 1:1.42. The gonado-somatic index (GSI) was ranged from 3.72 to 32.39 and showed significant monthly fluctuations (p<0.05). A sharp decline of GSI during May and June indicates the peak spawning of B. gonionotus in the study site. During the study the fecundity of the fish was ranged from 46145 to 353969 and the highest fecundity was recorded in the months of May. The findings of the present study would be helpful for the sustainable management of B. gonionotus in the freshwater ecosystem of Bangladesh and elsewhere.
J Bio-Sci. 30(1): 101-114, 2022 (June)
Prevalence and Clinical Features of Cardiac Murmur With Its Subtypes of Congenital Heart Disease in Rajshahi, Bangladesh
Authors: Chowdhury Md Nahid Islam , Ullah Md Anayet , Hossain Md Belal , Islam SM Shahinul
Published: January 2023

Congenital heart disease (CHD) is a congenital defect affecting the structure of the heart. Early detection can be done by auscultating the murmur and this could help to diagnosis the disease. This study was aimed to detect CHD by rapid evaluation of clinical features, findings and cardiac auscultation which will help to customize the future management plan in each CHD child and reduce the progression of complications and financial burden associated with CHD on this region over time. This descriptive cross-sectional study was conducted on children hospitalized to the paediatric department. A systematic sampling technique was implemented. Total 3978 children were taken during the study period among them 54 were detected as CHD. Total 3978 children under 10 years were examined during the study. Among them-murmur with CHD was found in 54 (1.36%) cases and it was found that 30 (55.6%) were male and most (53.7%) of them from rural area came from 42.6% middle socio-economic group. It was revealed that, among the study cases 40.70% had ventricular septal defect (VSD), 63% had rapid breathing regarding clinical presentation. Regarding clinical findings among the study cases 33 (61.10%) had chest retractions. Among 54 murmur positive cases 29 (53.70%) had pansystolic murmur which help to assess regarding CHD before completing echo. Congenital heart disease, especially in the newborn era, is a pediatric cardiology emergency due to the high morbidity and mortality rates. This research could aid in the early diagnosis of CHD and save the lives of youngsters.
J Bio-Sci. 30(1): 115-121, 2022 (June)
Chemo-Radiotherapy Induced Oral Complications and Their Care in Cancer Patients
Authors: Abbasi MM Alamgir Siddique , Ali Mir Nowazesh , Islam SM Shahinul
Published: January 2023

The purpose of this study was to evaluate a randomized control trial protocol to assess the effectiveness of an oral care protocol on chemotherapy- and/ or radiation therapy-induced oral complications in cancer patients. It was a randomized, outcome assessor blinded study. Patients were randomly allotted to a control and intervention group. Out of 68 patients 25 patients were treated only by radiotherapy, 32 patients were treated only by chemotherapy and 11 patients received both radio and chemotherapy. Most of the patients developed sensitivity, altered taste, oral thrush, mucositis, trismus and xerostemia during and after palliative treatment. Here patients having pain during therapy 22.01% and 30.09% before therapy, patients had a change of taste after therapy86.8% and 63.2% had a change of taste during therapy, patients had developed mucositis before therapy 4.4% and 64.7% had developed mucisitis during therapy, patients had developed trismus before therapy 8.8% and 42.6% had developed trismus during therapy. Here most of the respondents had inadequate knowledge and practice about oral care but there was no correlation between family histories of cancer. Under this study 27 staff nurses were working in radiation/chemotherapy oncology areas from the tertiary levels of hospitals. Here 51.3% nurses had a very poor knowledge regarding oral care and the major (81.0%) groups of them were suggested for training in the specific area. On the basis of survey report the respondent groups of nurses provided information are the main source of oral care information. The association between selected demographic factors data on age and education were also recorded. The result shows there was no correlation between family history of cancer patients and enough knowledge of the respondent groups. From this study it may be suggested that proper knowledge should be provided to the peoples to prevent major oral diseases specially for cancer in future in Bangladesh.
J Bio-Sci. 30(1): 143-153, 2022 (June)
Association Between Gross Motor And Intellectual Functions Among Children With Cerebral Palsy
Authors: Saad Tania , Fatema Kanij , Islam Kazi Ashraful , Uddin Mohammad Zahir , Khan ARM Sakhawat Hossain , Khan Mohammad Monir Hossain , Akhter Shaheen
Published: January 2023

Background: Cerebral Palsy (CP), a complex neurodevelopmental disorder in children, is often accompanied by comorbidities like intellectual impairments besides core motor dysfunction.
Aims: To assess the relationship between gross motor and intellectual functions among the children with CP.
Methods: A cross- sectional study was carried out in the Institute of PaediatricNeurodisorder and Autism (IPNA), BSMMU, Dhaka, during Oct. 2017 to May 2018 including 82 children up to 12 years of age having CP. The gross motor function of all the children was evaluated using GMFCS. Psychological assessment was done by professional psychologist using age specific psychometric tools.
Results: One third of the children (39.0%) belonged to age 2-4 years. Male to female ratio was 1.7:1. More than three fourths of the children (85.4%) were of term gestational age. Perinatal asphyxia (PNA) was associated in 92.7% children.More than half of the children (57.3%) had spastic quadriplegia. Almost half of the children (48.8%) GMFCS level was II and 28.0% children were of GMFCS level III. Nearly a half (48.8%) of the children was with mild intellectual impairment and 22.0% were with moderate intellectual impairment. There is a significant negative Spearman’s correlation (r=-0.639; p=0.001) between GMFCS level and intellectual level.
Conclusion: More severe motor impairments in CP might be associated with higher intellectual dysfunction.
J Dhaka Med Coll. 2021; 29(1): 9-15
Clinico-Epidemiologic Profile And Treatment Outcomes of Pemphigus Vulgaris: A Study in a Tertiary Care Center
Authors: Mahmud Md Mostaque , Hazra Samaresh Chandra , Chowdhury Md Mostaque Hassan , Khan Aziz Ahmed , Mamun Md Abdullah Al
Published: January 2023

Background: Pemphigus vulgaris is an autoimmune, potentially fatal vesiculobullous disease of skin and mucous membranes. The clinical profile and epidemiologic characteristics varies in patients to patients and in different communities. The aim of this study was to evaluate the clinical and epidemiological features, morbidity and mortality of pemphigus vulgaris and to compare that with other studies of different communities.
Methods: It was an observational study, conducted on 24 hospital admitted cases of pemphigus vulgaris at the department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. The duration of the study was from November 2018 to February 2020. Patients who were confirmed as pemphigus vulgaris both histopathologically and direct immunofluroscent test were included for that study.
Findings: The mean age (SD) of the patients was 47(15.5) years. Male outnumbered female in that study and male to female ratio was 1.4: 1. The mean (SD) duration of disease was 15(18.6) months. Pain (70.8) was the commonest symptoms. Trunk (92%) was the commonest cutaneous site of involvement followed by oral mucosa (71%). Oral prednisone was the mainstay of treatment and it was given to 24 (100%) of the patients. The immunosuppressant adjuvant was given in 79% cases. Azathioprine (62.5%) was the commonest of them. To avoid osteoporosis calcium supplement with or without vitamin D and bisphosphonate was given in 92% cases. The mean (SD) hospital stay was 5.4(3.3) weeks. Bacterial infection was the commonest complication and it was found in 2 patients. The mortality rate of that study was 4.16%.
Conclusion: pemphigus vulgaris is a dermatological emergency and the maximum patients need hospitalization for proper care. Hospital acquired infections are the common complication and that may leads to septicemia and death. To decrease the mortality of pemphigus vulgaris the care givers have to be more watchful about the potential of infections.
J Dhaka Med Coll. 2021; 29(1): 24-30
Correlation of Family History of Diabetes Mellitus With Hyperglycaemia in Acute Stroke in Non Diabetic Patient
Authors: Patwary Mohammad Shamsul Arefin , Ahasan HAM Nazmul , Miah Md Titu , Munmun Farzana Rahman , Begum Aysha , Shanchay Shamsuddoha Sarker
Published: January 2023

Background: Raised blood glucose is common in diabetic patients in early phase of stroke. It is also known that blood glucose level increases during acute stroke in non diabetic patients.
Objective: Objective of this study was to assess the association between family history of diabetes and newly developed diabetes, impaired fasting glucose, impaired glucose tolerance during acute stroke in non diabetic patients.
Methods: The purposive sampling method was applied to identify the patients by appropriate history taking about diabetes among the patients and their 1st degree relatives, documentary papers and laboratorial support evidenced by HbA1c level less than 6.5% (This means patient to be non diabetic). Data were collected from 100 patients. The data were collected by questionnaire, pre-tested earlier and data collection sheet illustrating the family history of diabetes mellitus and glycemic status during acute stroke among the nondiabetic patients. It was conducted from January, 2021 to July, 2021 in the Department of Medicine of Dhaka Medical College Hospital.
Results: The study found that, mean age of the patents was 61.76±7.33 years. Family history of Diabetes Mellitus (first degree relative) was found among 48% patients.52% patients did not give family history of Diabetes Mellitus. During analysis of the lab investigations among the participants, mean HbA1c level was found 5.69± 0.65 mmol/L which was found normal among the entire patient group. Patients Fasting Blood Sugar (FBS) was tested and mean FBS level was 5.94±0.86.Among the respondents 48% gave family history(1st degree relative) of Diabetes of which 8.3% revealed normal glycemic status , 66.7% showed IGT and 25.0% were diabetic. On the other hand 52% respondents had no family history of Diabetes, among them 50% showed no glycemic abnormality, 42.3% showed IGT and only 7.7% were diabetic.
Conclusion: In a nutshell, the study finds that, in patients with no history of diabetes who have acute stroke, may develop moderately elevated glucose levels and it is significantly higher in those who have family history of diabetes mellitus.
J Dhaka Med Coll. 2021; 29(1): 38-42
Clinical Presentation and Sonographic Evaluation of Biliary Ascariasis in A Tertiary Care Hospital
Authors: Gain Gobinda , Ahmed Farid , Paul Pinaki , Siddiki Ashfaque Ahmed , Hasan Rashedul , Mamun SK Abdullah Al , Sarker Harendro Nath , Rahman Saiyeedur , Biswas Prodip Kumar , Rahman Muhammad Faizur , Kabir AKM Humayon , Tulsan Suresh Kumar , Alam Ferdous
Published: January 2023

Background: Infestation with Ascaris lumbricoides is worldwide. About one fourth of the world’s population is known to be infected by ascariasis. It is endemic in various parts of Bangladesh.
Objectives: To study the various types of clinical presentations, socio-demographic background and sonographic patterns of biliary ascariasis.
Materials and Methods: Fifty cases of biliary ascariasis were studied over a period of 2 years, July 2011 to June 2013. All the patients were adult with age 18 years or above. Clinically suspected and ultrasonography evidenced cases of biliary ascariasis were taken as sample in this study.
Results: Mean age (mean ± SD) of presentation was 35.3 ± 15.9 years and female were 80%. Ninety percent of patients were from rural areas and 80% were bearing a lower class socioeconomic background. The most common presentation was upper abdominal pain in 100% of patients. History of worm emesis was present in 34% and previous biliary tree pathology in 24% of patients. Ultrasonography demonstrated the commonest site of worm entrapment was common bile duct in 76% of patients and the commonest pattern was stripe sign pattern in 56% of patients.
Conclusion: In endemic countries, ascariasis should to be suspected in patients with biliary disease, especially if there is history of emesis of worm or previous history of biliary tree pathology. Ultrasonography is a reliable, easily available and relatively inexpensive modality of investigation for suspected biliary ascariasis.
J Dhaka Med Coll. 2021; 29(1): 61-67
Pregnancy Related Acute Kidney Injury: A Multicenter Prospective Observational Study From Bangladesh
Authors: Faisal Amanur Rasul Md , Abdullah Mohammad Shayekh , Bahar Hijbul , Mullah Shahida , Ahmed Syed Imtiaz , Singha Anirban Kishor , Badal Md Dilder Hossain , Rahman Md Saidur , Rahman Md Hafizur
Published: January 2023

Background: Acute kidney injury (AKI) is one of the most challenging and serious complications of pregnancy which imposes a heavy burden of maternal morbidity and mortality if its diagnosis and treatment are delayed.
Objective: This prospective study intended to determine the frequency, etiology and outcomes of the patients of pregnancy related acute kidney injury (PRAKI) in different tertiary care hospitals in Bangladesh.
Methods: This was a prospective study of patients with pregnancy related complications leading to acute kidney injury admitted in selected departments of different tertiary care hospitals in Bangladesh for a period of one year (October 2018 to September 2019). Patients were included in this study who were healthy previously and developed acute kidney injury (serum creatinine >70.72 mmol/l) due to pregnancy related complications. Recruited patients were monitored after 3 months with a view to exclude chronic kidney disease.
Result: A total of 351 patients with pregnancy and puerperium were observed, of these patients studied, 34 (9.2%) had pregnancy-related AKI. In 32 patients who completed the study, the mean age was 27.2±6.2 years. There were more subjects belonging to the rural area (68.8%) and nineteen (59.4%) of patients were below primary level of education. Most of the study subjects from lower socioeconomic status (56.2%). Twenty-one (65.5%) patients were multigravida, and mean parity of the patients included in this study was 1.7±0.8. Nineteen (59.4%) patients did not receive any antenatal care. PRAKI occurred during the post-partum period in 53.2% of the cases, 21.9% in third trimester, and 24.9% in first and 2nd trimester. The most common cause of PRAKI in our study was sepsis, occurring in about 15 patients (46.9%). Most common presentation of PRAKI was oliguria (87.5%) and edema (84.3%). Mean hemoglobin level was 7.8 ±1.7 gm/dl and creatinine level was 573±407 μmol/l. A majority of the patients (81.25%) underwent hemodialysis, while others were treated with conservative management only. At the three-month follow-up, complete resolution of AKI was observed in 62.5% patients, progressed to CKD in 25% whereas mortality occurred in 12.5% patients. In univariate analysis, inappropriate antenatal care (p- 0.0018), low mean platelet count (p-0.00001), higher serum creatinine (p-0.00004), dialysis at presentation (p-0.0154), and septicemia (p-0.0487), have significant effect.
Conclusion: Pregnancy related AKI is still a critical situation in developing countries and rare entity in developed countries. Maternal mortality has decreased but sepsis still accounts for majority of cases of PRAKI. Therefore, early diagnosis and treatment is the need of the hour.
J Dhaka Med Coll. 2021; 29(1): 76-81
Variation of Serum Zinc Concentrations Among Kala-Azar Endemic and Nonendemic Population in Bangladesh
Authors: Basu Kamalesh Chandra , Hoque Mohammad Mahfuzul , Datta Ponkaj Kanti , Samsuzzaman Sheikh Mohammad , Hasan Mohammad Jahidul , Rahman Muhammad Faizur , Khan Mohammed Masudul Hassan , Saifullah Md , Kamal Mohammad Mostafa , Hossain Mohammad Zaid , Miah Md Titu
Published: January 2023

Background & objectives: Visceral Leishmaniasis (VL) or Kala-azar is a deadly disease putting 350 million people from 88 countries at risk. In Bangladesh, 45 districts are endemic. Zinc is an essential trace element and its relevance for proper functioning of the entire immune system is already well documented. Though low serum zinc levels have been reported in many parasitic diseases, limited information is available regarding zinc status in human leishmaniasis. This study was conducted to evaluate the zinc level in endemic and non-endemic population of kalaazar.
Methods: This cross-sectional study was conducted to assess the serum zinc concentrations in kala-azar endemic and non- endemic population of 06 to 60 years of age range during the period of July 2014 to June 2015.Venous blood was collected from 92 subjects to estimate serum zinc concentrations.
Results: Mean Serum zinc levels were found 63.66 microgm/dl in kala-azar patients of endemic area, 69.44 microgm/dl in kala-azar endemic populations and77.34 microgm/dl in non-endemic populations.
Conclusion: The average serum zinc concentrations is lower in populations of kala-azar endemic zone compared to populations from kala-azar nonendemic zone. It was also found that kala-azar patient had lower zinc concentrations compared to non-kala-azar patients. There may have potential association of low zinc level and occurrence of kala-azar.
J Dhaka Med Coll. 2021; 29(1): 111-117
The Metacognitive Strategy to Achieve Listening Comprehension in Kulni Modern Islamic Boarding School
Authors: Munawar Tanjung Muhamad Farhan , Heryatun Yayu , Sa'diah Siti
Published: January 2023

Metacognitive is the process of thinking about our minds, which is how a process, and control that information to find new understanding/knowledge and seek relationships with other knowledge. The purpose of this study is to discover how students in class XI of Kulni Modern Islamic Boarding School at Cikande, Serang Banten in use English listening metacognitive strategies, as well as the differences in improving English listening comprehension among students before and after receiving metacognitive learning. The population of this study included 61 students from class XI of  Kulni Modern Islamic Boarding School at Cikande, Serang Banten.  The sample consisted of 29 students from A class XI. The researcher used quantitative data analysis in this study. Data is gathered by administering tests to the class. There are two kinds of tests: pre-test and post-test. According to the study's findings, the average pre-test score at researcher Modern Islamic Boarding School at Cikande, Serang Banten was 40.41, and the average post-test score in the experimental class was 57.21. Based on the data presented above, it is possible to conclude that there is a 41.5 percent change in learning outcomes. Based on the result of the study, applying metacognitive strategies for learning can help students become interested in listening activities and can be an alternative innovation in learning listening.
Developing “Reverb English” Textbooks for Kindergarten Students: Is It Effective?
Authors: Khittahira Fikra Raushani , Tyas Peptia Asrining
Published: January 2023

English is one of the foreign languages taught in Indonesia. It has separated curriculum from other subjects which are taught in primary, secondary, and high schools by using English textbooks. However, English textbooks are limited to be developed in Kindergarten area. Therefore, this research conducted and aimed to develop adequate English textbooks based on Kindergarten syllabus which are annual and semester programs by the school. The researcher took the group A and B learners of Kindergarten students at TK Negeri Pembina 1 Malang year 2021/2022. The researcher involved 70 students as the participants. Research and Development (R&D) was conducted in this research with the ADDIE model. The instruments of the research were observation and interviews both teacher and students. The data analysis was obtained from the expert validation checklist also the transcription of the result from the interview with both teachers and students. Findings indicate that “Reverb English” textbooks are feasible and effective during the English teaching-learning process in the classroom for kindergarten students. It can help them to learn faster by visualizing the pictures and words in the book.
Evaluation of Zerumbone as an EGFR Tyrosine Kinase Inhibitor by Molecular Docking Method
Authors: YONAR Dilek , BABA Burcu , KARAYEL Arzu
Published: January 2023

Objective: EGFR-TK domain is of great importance in the initiation and progression of various cancer types, especially lung cancer. The existing EGFR-TK inhibitors have numerous side effects, which make them improper to be utilized as cancer therapeutics. In this study, we aimed to analyze the activity of zerumbone as an anticancer agent targeting EGFR by molecular docking approach and to evaluate its activity in comparison with curcumin.

Material and Method: MEP and HOMO-LUMO analyses were achieved at B3LYP/6-31G(D,P) level to evaluate electrostatic interactions that affect binding of EGFR with zerumbone and curcumin. Their binding energies were determined by molecular docking and compared with erlotinib as reference ligand.

Result and Discussion: Docking studies showed higher bindings (lower binding energy) for curcumin and zerumbone with binding energies -8.0 and -7.6 kcal/mol, respectively, compared to erlotinib (-7.54 kcal/mol). However, there is no significant difference between them. The ΔE energy gap of zerumbone and curcumin were 5.09 and 3.68 eV which implies that these compounds have more stability but less electronegativity in comparison with erlotinib (ΔE=2.22eV). Also, zerumbone showed strong hydrogen bond interactions with EGFR, making it candidate as EGFR inhibitor, as did both in curcumin and erlotinib. It was concluded that zerumbone may have potential for inhibitory activity against EGFR-TK.
A Versatile, Low-Cost, Three-Dimensional-Printed Ultrasound Procedural Training Phantom of the Human Knee
Authors: Day Alvin Lee , Barger John Bradley , Resuehr David
Published: January 2023

The use of musculoskeletal ultrasound is expanding in many medical disciplines, and simulation trainers have been successfully employed to help practitioners learn various ultrasound techniques. While there are fewer commercial trainers in musculoskeletal ultrasound than other ultrasound modalities, the ones that do exist can be prohibitively expensive. Several less expensive phantom trainers have been described in the literature, including those made of ballistic gelatine. The authors present a three-dimensional printed knee phantom that was overlaid with ballistic gelatine as a viable option for training.