bluuebunny/crossref_metadata_2025 huggingface dataset:
Realising Female Inheritance Rights in South Eastern Nigeria: The Imperativeness of Going beyond Legal Rhetoric
Authors: Eyongndi David Tarh-Akong Eyongndi , Opara Faith Nwayemogho , Oladele Olayiwola Owoade , Agbu David Andrew , Ajayi Mary-Ann Onoshioke
Published: June 2024

The decision of the Supreme Court of Nigeria in Ukeje v. Ukeje is regarded as the ultimate liberation of females, particularly in Eastern Nigeria from discriminatory customary law which disentitles them from inheritance in cases of intestate succession. While this decision buttresses the non-discriminatory provision of section 40 of the 1999 Constitution of the Federal Republic of Nigeria, making a judicial pronouncement is different from giving effect to same. The question, therefore, is how can this decision be effectuated especially in rural areas where the people jealously guard their traditional beliefs, values and customary practices? This paper, through desk-based method with reliance on primary and secondary sources of data, interrogates how the discriminatory inheritance cultural beliefs (volksgeist) and practices of the Igbo people can be synergised with the decision in Ukeje v. Ukeje. It argues that this will require extra-legal mechanisms like gender equality sensitisation campaigns, communal reorientation through enlightenment, and dialogue with traditional institutions. It therefore recommends dialoguing with traditional institutions and reorienting the community as measures to be adopted in effectuating the judgment in the rural Igbo communities where same is opposed to their volksgeist towards fostering gender equality which is central to Sustainable Development Goal 5.
Development of technology and study of combination tablets of prednisolone and loratadine with modified release
Authors: Davydova V. V. , Stepanova E. F. , Shevchenko A. M. , Chiriapkin A. S. , Pleten A. S. , Prokopov A. A.
Published: June 2024

Background. Allergies are a global medical and social problem. According to international statistics, the number of allergic diseases has increased dramatically in recent decades. In recent years, the largest increase in the incidence of bronchial asthma, pollinosis and dermatoses has been noted. Currently, significant success has been achieved in understanding the causes and mechanisms of allergic inflammation and in forming approaches to the treatment of allergic diseases. Among second-generation antihistamines, loratadine, an effective antiallergic drug, is excreted. However, in the pharmaceutical market, the range of its dosage forms is small – the drug is available in the form of tablets, capsules and syrup. Prednisolone is a drug that quickly copes with an allergic reaction and helps prevent unwanted complications. In this regard, it is proposed to develop a tablet dosage form of a combined composition. Combined technology was used in the development of model compacted tablet formulations. The release and assay of active ingredients from model tablets of different compositions were determined using the Dissolution test and by high performance liquid chromatography, respectively.

Aim. Development of loratadine and prednisolone tablets of the combined structure.

Materials and methods. Combined technology was used in the development of model compacted tablet formulations. The release of the active ingredients from the tablets was confirmed by the Dissolution test in HCl dissolution medium (0.1 M). The assay of the active ingredients in the formulation was determined by high performance liquid chromatography.

Results. The conducted studies made it possible to determine the composition of the combined tablets, which ensures the initial release of prednisolone and the subsequent release of loratadine. In the Dissolution test, the chosen model composition of tablets No. 1 provided release of 84.4 % prednisolone and 81.5 % loratadine, respectively, at the 10th and 30th minutes.

Conclusion. The possibility of preparing a tablet dosage form providing a sequence of release of active substances has been demonstrated.
Autoimmune/inflammatory syndrome induced by adjuvants in a patient after implantation of a polypropylene mesh for inguinal hernia repair (clinical case)
Authors: Matveev V. Yu. , Trushina O. V. , Shchekochikhin D. Yu. , Babadaeva N. M. , Gracheva E. V. , Shilova A. S. , Nesterov A. P.
Published: June 2024

Aim. To report a clinical case of autoimmune/inflammatory syndrome, induced by adjuvants in patient after polypropylene mesh implantation for inguinal hernia repair.

Materials and methods. Patient Z., male, 68 years old, was admitted to the hospital presenting muscle weakness and progressive dyspnoea. Interview and physical exam revealed signs of cognitive impairment and memory loss, proximal muscle weakness. Differential diagnosis was made to clarify genesis of symptoms, to rule out polymyositis, other systemic connective tissue diseases, oncologic diseases, hypothyroidism, infectious diseases.

Results. Creatine kinase, thyroxine, thyreothropic hormone levels were normal. Clinical and immunological investigation revealed no data on polymyositis or any other systemic connective tissue disease. Yersiniosis, salmonellosis, malaria were ruled out. Chest CT scan, abdomen CT scan, gastroscopy, colonoscopy no data on the presence of malignant neoplasms. PSA level were normal. Electroneuromyography revealed signs of symmetrical axonal type damage to the motor portion of the ulnar nerves on both sides, and demyelinating type damage to the sensory portion. Prednisolone therapy was started at a dose of 40 mg per 24 hour (0.5 mg per kg), which lead to a significant clinical improvement. Based on the therapy response and positive diagnostic criteria (clinical manifestation after polypropylene mesh implantation, typical clinical manifestation – muscle weakness, chronic fatigue, cognitive impairment, neurological manifestations associated with demyelination) patient was diagnosed with autoimmune/inflammatory syndrome, induced by adjuvants (ASIA) after polypropylene mesh implantation for inguinal hernia repair.

Conclusion. This clinical case report demonstrates possibility of a persistent course of the disease (symptoms were present for 15 years). Feature of this case is partial clinical improvement due to long-term uncontrolled dexamethasone use, which was prescribed empirically.
Genetic Associations of Anhedonia: Insights into Overlap of Mental and Somatic Disorders
Authors: Kasyanov Evgeny , Pinakhina Darya , Rakitko Aleksandr , Vergasova Ekaterina , Yermakovich Danat , Rukavishnikov Grigoriy , Malyshko Larisa , Popov Yaroslav , Kovalenko Elena , Ilinskaya Anna , Kim Anna , Plotnikov Nikolay , Neznanov Nikolay , Ilinsky Valeriy , Kibitov Aleksandr , Mazo Galina
Published: June 2024

BACKGROUND: Anhedonia is characterized by a reduced ability to anticipate, experience, and/or learn about pleasure. This phenomenon has a transdiagnostic nature and is one of the key symptoms of mood disorders, schizophrenia, addictions, and somatic conditions.
AIM: To evaluate the genetic architecture of anhedonia and its overlap with other mental disorders and somatic conditions.
METHODS: We performed a genome-wide association study of anhedonia on a sample of 4,520 individuals from a Russian non-clinical population. Using the available summary statistics, we calculated polygenic risk scores (PRS) to investigate the genetic relationship between anhedonia and other psychiatric or somatic phenotypes.
RESULTS: No variants with a genome-wide significant association were identified. PRS for major depression, bipolar disorder, and schizophrenia were significantly associated with anhedonia. Conversely, no significant associations were found between PRS for anxiety and anhedonia, which aligns well with existing clinical evidence. None of the PRS for somatic phenotypes attained a significance level after correction for multiple comparisons. A nominal significance for the anhedonia association was determined for omega-3 fatty acids, type 2 diabetes mellitus, and Crohn’s disease.
CONCLUSION: Anhedonia has a complex polygenic architecture, and its presence in somatic diseases or normal conditions may be due to a genetic predisposition to mood disorders or schizophrenia.
Reducing blood product waste through the implementation of a four-step protocol during the COVID-19 pandemic
Authors: Dikici İbrahim Halil , Özpolat Sahre G.
Published: June 2024

Purpose: Blood banking is critical for patients who require transfusions. Blood banks must stock blood products and update their inventory depending on the transfusion demands of hospitals. This demand subject to fluctuations caused by factors such as seasonal variations, emergent medical situations, and disasters. Unexpected changes in transfusion demand also have the potential to affect the number of waste blood products, thereby exacerbating the economic burden borne by blood centers. Our aim in this study is to reduce the destruction rates of blood products.
Materials and Methods: In this study, we evaluated the number and cause of discarded blood products in a tertiary hospital in the southeast of Turkey between 2019 and 2022. We also analyzed the effect of the COVID-19 pandemic on blood product waste. In addition, we developed a four-step protocol to reduce wasted blood products in our center.
Results: In the first year of the study, the waste/stock (W/S) ratio was 3.0% for packed red blood cells (pRBCs) and 9.2% for platelets (PLTs). However, this ratio increased to 3.2% for pRBCs and 10.1% for PLTs during the COVID-19 restrictions in 2020. Upon the implementation of the four-step protocol, the W/S ratio decreased for both pRBCs (2.3%) and PLTs (6.9%) in 2021, but this trend continued for only pRBCs (1.8%) in 2022.
Conclusion: The number of waste products increased during the COVID-19 restrictions in our center. After we developed the four-step protocol, the waste of pRBCs decreased for two consecutive years, but this was not observed for other blood products. To verify our results, the presented 4-step protocol should be tested in a larger center over a longer period.
Kajian Dampak Lingkungan Terhadap Pembangunan Kantor Telecenter PT. X Di Tangerang
Authors: Alimuddin Alimuddin , Chayati Nurul - , Fachruddin Fachruddin - , Akbar Chaeka Fitria Ramadhania
Published: June 2024

Abstrak. Manusia diciptakan untuk mengatur alam semesta ini dengan cara menjaga dan melestarikan keberlanjutan lingkungan hidup sehingga kepedulian terhadap lingkungan hidup adalah suatu hal yang perlu dilakukan. Demikian juga dengan menjaga kelestarian lingkungan pada Kantor Telecenter PT. X di Kabupaten Tangerang. Tujuan dari kajian ini adalah menilai kualitas rona lingkungan awal dan memprediksi dampak yang akan terjadi serta merumuskan upaya-upaya meminimalisir dampak pada setiap tahapan kegiatan yang dilakukan. Metode yang digunakan adalah metode observasi, metode wawancara, dan pelingkupan. Hasil dari kajian ini adalah rona lingkungan awal pada lokasi kajian menunjukkan bahwa kualitas lingkungan dari segi komponen kualitas udara ambien, kebisingan dan kualitas air tanah berada dalam kategori baik. Secara umum upaya yang dilakukan untuk meminimalisir dampak negatif yang terjadi pada setiap kegiatan Pembangunan Kantor Telecenter PT. X di Tangerang dapat dilakukan dengan cara pendekatan sosial dengan masyarakat, melaksanakan kegiatan konstruksi hanya di siang hari, memprioritaskan masyarakat lokal sebagai tenaga kerja, optimalisasi penghijauan dalam lingkungan dan ruang terbuka hijau serta pengelolaan sampah yang baik serta fasilitas kebersihan yang lengkap agar tidak terjadi gangguan terhadap kesehatan masyarakat. Study Of Environmental Impact on The Construction of PT. X In Tangerang Abstract. Humans were created to manage this universe by protecting and preserving the sustainability of the environment so that caring for the environment is something that needs to be done. Likewise with preserving the environment at the Telecenter Office of PT. X in Tangerang Regency. The purpose of this study is to assess the quality of the initial environmental baseline and predict the impacts that will occur as well as formulate efforts to minimize the impact at each stage of the activities carried out. The method used is the quantitative descriptive analysis method. The result of this study is that the initial environmental baseline at the study location shows that the environmental quality in terms of the components of ambient air quality, noise and groundwater quality are in the good category. In general, the efforts made to minimize the negative impacts that occur in every activity of PT. X in Tangerang can be carried out by means of a social approach with the community, carrying out construction activities only during the day, prioritizing local communities as workers, optimizing greenery in the environment and green open spaces as well as good waste management and complete cleaning facilities to prevent disturbance to public health.
PERFORMANCE COMPARISON OF ECC LIBRARIES FOR IOT DEVICES
Authors: Çekiş İsmet Kaan , Toros Armağan , Apaydın Nimet , Ozcelık İlker
Published: June 2024

As the prevalence of IoT devices increases, the need for strengthening security becomes inevitable. Lightweight encryption solutions play a pivotal role, particularly in addressing security concerns associated with IoT authentication and privacy. This study concentrates on the performance evaluation of open-source and lightweight encryption libraries. Various open-source encryption libraries underwent testing on a Raspberry Pi, revealing noteworthy variations in key generation, signing, verification times, and memory usage. This research provides comprehensive assistance for the selection of encryption libraries for IoT applications. Consideration extends beyond library performance, encompassing factors such as user base and documentation quality, to deliver optimal security solutions
Generation of C-terminal Sequences of Human Renalase-1 and Renalase-2 Encoded by Alternative Exons
Authors: Fedchenko V.I. , Kaloshin A.A. , Medvedev A.E.
Published: June 2024

A method for generation of C-terminal amino acid sequences fused to dihydrofolate reductase (DHFR) and specific for RNLS1 and RNLS2 isoforms of renalase is described. It includes synthesis of nucleotide sequences of alternative exons of RNLS1-9ex and RNLS2-10ex, determining the differences in the primary structure of these proteins, their fusion with the coding sequence of DHFR and expression of these genetic constructs in cells of the E. coli Rosetta cells. Chromatographic purification on a column containing Ni Sepharose resulted in highly purified preparations of reombinant ReI-9ex and ReII-10ex proteins with an electrophoretic purity of about 95%.
The prevalence of congenital heart disease in newborn detected by pulse oximeter screening test at 24 hours of birth and its correlation with clinical findings and ECHO
Authors: Suresh Vindhya , Mysore Ramraj Savitha
Published: June 2024

Background: Detecting congenital heart disease (CHD) early is crucial for better outcomes, but most newborns show no symptoms. Newborn screening for CHD can identify such cases preventing serious consequences. This study aims to determine CHD prevalence and evaluate the effectiveness of pulse oximeter screening and clinical examination, correlating them with echocardiography findings.
Methods: A cross-sectional study was conducted to screen for CHD in all newborns born in our institution over a period of 3 months. A sample of 660 newborns were screened by pulse oximeter screening and clinical examination after random sampling.
Results: Comparison of baseline data like age distribution in mothers, gender and gestational age were comparable between newborns with CHD and those without CHD. A total of 8 CHDs were picked up after screening 660 newborns screened during a period of 3 months. CHDs that were picked up included hypoplastic left heart syndrome, pulmonary atresia, bicuspid aortic valve, transposition of great arteries, coarctation of the aorta, and other complex CHDs. It was found that either clinical examination or pulse oximeter screening has higher sensitivity than pulse oximetry screening or clinical examination alone.
Conclusions: For identification of a CHD in newborns after 24 hours of birth the order of preference for screening based on sensitivity is as follows-either pulse oximeter screening or clinical examination >clinical examination >pulse oximeter screening >pulse oximeter screening and clinical examination.
Transient synovitis of hip joint following COVID-19 infection in a child with Hodgkins lymphoma
Authors: Vishwanathan Sanjana , Bhurat Rishab , Francis Litha , Murali Arunan , Janarthanan Mahesh , Jayaraman Dhaarani
Published: June 2024

Transient synovitis is a common cause of hip pain in children. COVID-19 pandemic affected pediatric cancer patients more often that general pediatric population. COVID-19 has been associated with various musculoskeletal symptoms including synovitis. Radiological assessment of these symptoms can contribute significantly in management of such patients. We report a case of transient synovitis of hip joint following COVID-19 infection in a 10-year-old boy with Hodgkins’s lymphoma. He presented with fever and myalgia, found to be positive for COVID-19, managed conservatively. Two weeks later presented with right hip pain and limping. He was found to have restricted joint mobility and hip tenderness. Magnetic resonance imaging (MRI) pelvis was done which showed minimal right hip effusion and synovial thickening and enhancement. He was managed conservatively and recovered completely.
The cost-effectiveness of an additional surgical scrub in reducing prosthetic joint infections in total hip and knee arthroplasty
Authors: Tye Cooper , Lawand Jad , Moretti Vincent
Published: June 2024

Background: Surgical skin preparation prior to total knee and hip arthroplasty is an important step in infection prevention. Compared to a single application, repeat skin preparation after draping demonstrates greater efficacy in reducing the overall occurrence of surgical site infections in total joint arthroplasty. We sought to find if the addition of an extra surgical scrub after draping is a cost-effective means of decreasing prosthetic joint infection (PJI), and if so, under what conditions it would be most cost-effective.
Methods: We employed a model to assess the cost-effectiveness of repeat skin preparation in total knee and hip arthroplasty. This model determines a threshold at which the expenses associated with a new intervention is offset by its ability to reduce overall costs. Literature review and records from our institution were used to draw average expenses for treatment of PJI, as well as surgical prep scrubs, to evaluate at their cost-effectiveness. We also compared against hypothetical higher and lower costs and infection rates to gain further information on the additional surgical prep’s cost-effectiveness.
Results: Each of the surgical scrubs is cost-effective at our institution's cost when an absolute risk reduction (ARR) of 0.01% is achieved. The cost-effectiveness was also noted with hypothetically higher infection rates and scrub cost prices. Lower potential two-stage revision costs make the additional surgical scrub less cost-effective. 
Conclusions: Our findings demonstrate that an extra surgical scrub can be cost-effective way of decreasing PJI across a variety of different surgical scrub prices, arthroplasty revision costs, and PJI rates.
A case control study to compare the effect of dynamisation of tibia nail in union of tibia shaft fracture versus non-dynamisation
Authors: Gunay Siddharth , Avhad Tanmay A. , Tungenwar Shubham , Jethlia Sanket
Published: June 2024

Background: Tibial shaft fractures are commonly treated with intramedullary nails (IMN), with union rates of 90-100%, but complications such as delayed union occur in up to 40%. The rise of technology and urbanization has led to an increase in road traffic injuries and deaths. The treatment of distal tibia fractures has undergone various modifications over the years, with emphasis on preserving local biology and soft tissue handling.
Methods: A retrospective case-control study involving 132 patients with closed or open grade 1 tibia shaft fractures was conducted from September 2021 to May 2022. Patients received tibia IMN with either dynamic locking (group A) or static (group B). Patients were evaluated for fracture healing and clinical condition, with variables including presence or absence of union and time to union. Follow-up clinical evaluations were conducted monthly for six months.
Results: The association between union of bones seen at 1.5 and 3 months between group A and group B was extremely statistically significant (p<0.0001).
Conclusions: Intramedullary nailing with dynamic nailing assemblies is safe and effective for closed or type I open tibial fractures with limited comminution. This approach may reduce complications and re-operations and allow for early weight-bearing. Proper management of tibial fractures requires an interprofessional team.
Hoffa’s fat pad ganglion cyst protruding from lateral retinacular rent: a case report
Authors: Narkhede Yogesh D.
Published: June 2024

Ganglion cyst in and around the knee are quite rare occurrences. They are usually encountered as incidental findings in magnetic resonance imaging (MRI), or in arthroscopy. They may originate from both the cruciate ligaments and the menisci, from the popliteus tendon and alar folds, infrapatellar fat pad of Hoffa, and subchondral bone cysts. Those cysts which arise from fat pad, present as palpable mass at the anterior aspect of the knee. 45-year male, presented with a painless gradually increasing swelling at the anterior aspect of the left knee of 11 months’ duration. Patient complaints of discomfort in the left knee, occasional pain on walking, and climbing stairs. MRI scan revealed a multilobulated, cyst with septations within the anterior aspect of the knee joint, just inferolateral to the patella, with deep extension into the infrapatellar fat pad, and superficial extension into the subcutaneous space across the retinaculum. Proper preoperative evaluation of MR images of these cases is very important. Subcutaneous extension through lateral retinaculum renders these cyst incomplete resection via arthroscopic excision. There-fore open excision was performed.
Analysis of holmes tremor deep brain stimulation of ventro-intermediate thalamic nuclei and posterior subthalamic area
Authors: Raju Venkateshwarla Rama
Published: June 2024

: Holmes tremor (HT) is rarely seen in Parkinson`s. In our recent investigation, we encountered a Parkinson patient with HT. The subject (patient) was diagnosed through HT-DBS ventro intermediate thalamic nucleus (VIM) plus posterior-sub thalamic-area (PSA) was done.

: the aim was to validate our results with clinical features, etiology, outcomes as of neuroimaging, plus therapy findings in Parkinson`s.

: Patient underwent numerous medications (Carbidopa, Levodopa, and mixed, benzazepines as well as tri-hexy-pheni-dyl). We applied the quantitative-techniques of Fahn-Tolosa-Marin Tremor-Rating-Scale (F.T.M.T.R.S) to measure the degree-of shaking-palsy/tremor. The scoring is a broadly utilized for measuring the tremor. The scale (measuring-tool) included the scoring-scale of the tremor site (portion A), the movement (portion B) plus functional-role (portion C). Subject scoring with F.T.M.T.R was56 plus he cannot handle the any objects, nor he sign nor scribbles nor he sign the signs nor draw the spirals-of-Archimedes. We measured the patients' Holmes tremor using F.T.M.T.R.S at 30, 90-, 180-, 365-, and 730-days following electrical stimulations via minimally invasive deep brain stimulators.

: On investigation, there was no improvement in symptoms reduction or restoration, increasing motor functioning restoration. There was no antiquity of consuming by means of neuroleptics and/or shaking palsy(tremor) persuading medicine in advance of or following the brain stem hemorrhage plus there was no genetic-hereditary and/or transmissible family-antiquity of the Parkinson`s disease (PD)and/or movement-disorders(MDs).

: The outcome demonstrated that the DBS reassured the patient's tremor throughout 730-days (i.e., 24 months – 2 years) follow-up passé or retro.
Profiling the toxicological landscape of herbal drugs
Authors: Prajapati Anil Kumar
Published: June 2024

Herbal drugs, also known as phytochemicals or botanical medicines, are a cornerstone of traditional healthcare, with the World Health Organization (WHO) noting their reliance by approximately 80% of the global population. Despite their historical and widespread use, the assumption of their inherent safety due to natural origins is misleading. The significance of toxicological profiling and standardization to ensure the safe use of herbal medicines. Challenges such as species substitution and adulteration highlight the urgent need for regulatory oversight and stringent quality control. Various bioactive compounds in herbs can pose severe health risks, necessitating comprehensive toxicity evaluations using OECD guidelines. Regulatory frameworks across different regions, including the FDA in the United States, EMA in Europe, and the Ministry of AYUSH in India, are pivotal in maintaining the safety and efficacy of these products. Strategies to mitigate herbal drug toxicity include standardization of manufacturing processes, adherence to Good Manufacturing Practices (GMP), robust regulatory compliance, extensive research on toxicity profiles, education of stakeholders, and vigilant monitoring of adverse events. These measures are essential to fostering the responsible use of herbal medicines and safeguarding public health.
A dinâmica da luta contra a corrupção na ucrânia: realizações, desafios e formas de os ultrapassar
Authors: Paryzkyi Igor , Balon Andriy , Udovychenko Oleksandra , Tumalavičius Vladas , Shvedova Hanna
Published: June 2024

No contexto da luta ambígua contra a corrupção na Ucrânia, a análise da dinâmica deste fenómeno torna-se uma tarefa fundamental. O objetivo do estudo é analisar a dinâmica da luta contra a corrupção na Ucrânia, identificar os desafios e as realizações, bem como propor estratégias eficazes para superar este fenómeno social. A investigação utiliza uma abordagem metodológica combinada, incluindo inquéritos estruturados, análise do Índice de Perceção da Corrupção, análise temática da literatura, ou seja, métodos de estudo quantitativos e qualitativos. Tendo em conta os resultados dos inquéritos da Agência dos Estados Unidos para o Desenvolvimento Internacional e a análise do Índice de Perceção da Corrupção, o estudo tem como objetivo revelar a essência dos desafios, das realizações e das possíveis formas de ultrapassar as manifestações de corrupção. Os resultados revelaram uma variedade de desafios que a sociedade ucraniana enfrenta na luta contra a corrupção, incluindo a burocratização, a reforma judicial inacabada, a interferência política e um quadro institucional fraco. Apesar disso, o trabalho revela a dinâmica da perceção da corrupção, analisa as realizações e destaca os principais aspectos que devem ser tidos em conta no desenvolvimento de estratégias para superar este fenómeno. A conclusão sublinha a necessidade de repensar sistematicamente as abordagens de combate à corrupção na Ucrânia. As estratégias e recomendações propostas podem servir de base para outras acções das autoridades e do público na formação de uma política anticorrupção eficaz.
Políticas etno-nacionais: dimensões jurídicas e proteções para os povos indígenas
Authors: Kovnyi Yurii , Roshkanyuk Vadym M. , Panov Alen V. , Vovk Mariia , Dubova Kateryna
Published: June 2024

O problema da observância dos direitos dos povos indígenas é um desafio urgente para o sistema jurídico moderno. O objetivo deste estudo é analisar os aspectos jurídicos da política etno-nacional, especialmente no respeito à proteção dos direitos e interesses dos povos indígenas. O estudo baseia-se nos métodos científicos de síntese, de análise da regulamentação em vigor literatura científica. A análise da literatura científica foi efectuada de acordo com os critérios de seleção dos estudos pertinentes e do seu tratamento. Os resultados mostram termo “política etno-nacional” define um conjunto de medidas governamentais destinadas a responder às necessidades das comunidades étnicas e indígenas no âmbito do Estado-nação. Observa-se que a trajetória de desenvolvimento da sociedade tem limitado a proteção dos direitos dos povos indígenas. Um passo importante para contrariar esta situação foi a adoção da Convenção n.º 169 pela Organização Internacional do Trabalho, que definiu abordagens para a proteção e integração dos direitos dos povos indígenas. O autor observa Convenção, bem como a Declaração dos Direitos dos Povos Indígenas, contribuíram para melhorar a sua proteção jurídica e estatuto social, embora alguns países da UE não tenham adotado as disposições da Convenção. É de notar direito à autodeterminação preenche outros direitos, incluindo o direito à cultura autonomia. A Declaração reconhece a ligação entre a autodeterminação, a autonomia preservação da identidade indígena. As conclusões sublinham as iniciativas e a jurisprudência regionais, incluindo as decisões do Tribunal Interamericano dos Direitos do Homem, que confirmam os direitos dos povos indígenas à terra e aos recursos.
Organizational and legal aspects of digitalization of public authorities in Ukraine
Authors: Pendiura Maksym , Lukashenko Alona , Lapka Oksana , Kryvenko Valeriia , Tykhomyrov Denys , Savelieva Inna
Published: June 2024

The scientific work is dedicated to highlighting the organizational and legal aspects of digitalization of state authorities in Ukraine. It is noted that these public relations in the conditions of global digital transformation structurally consist of relations arising in connection with the implementation of executive and administrative activities of state authorities, the provision of electronic administrative services and the provision of rights and freedoms of citizens through the use of information and communication technologies. It is indicated that the key imperatives of state management of digital development are end-to-end digitalization, promotion of the development of the information society, stimulation of international digital cooperation, provision of information and communication technologies to all segments of the population, formation of digital skills, provision of digital security and protection of digital rights and freedoms of citizens. Prospective directions for strengthening the digital capacity of state authorities and improving their communication capabilities in Ukraine were identified, and the importance of the appropriate modern legal basis for the system of digitization of state authorities and state administrative services was emphasized.
Construção da imagem corporal em mulheres com experiência de violência sexual na infância e/ou adolescência
Authors: Barros Pessôa Adrielle , Costa de Souza Marcio , Assis Brasil Sandra , Graça Marinho Márcia Cristina
Published: June 2024

Este artigo se trata de um relato de experiência que tem como objetivo apresentar e discutir experiências de violência sexual em mulheres cisgêneros ocorridas na fase da infância e/ou adolescência e repercussões na construção de suas imagens corporais. A escuta a essas mulheres foi realizada a partir da experiência de uma psicóloga residente durante o período da Residência Multiprofissional em um Hospital e uma Unidade de Saúde da Família (USF), localizados em Salvador, Bahia, Brasil. A partir da utilização das tecnologias leves e da abordagem da Clínica dos Afetos, a escuta dos relatos das mulheres revelou histórias de violência sexual na infância praticadas, em sua maioria por pais e padrastos, desproteção, abandono e violência praticadas pelas figuras maternas, ausência de atenção e acompanhamento psicossocial às suas situações de violência, bem como desvalorização de sua autoimagem e imagem corporal. As experiências de violência sexual relatadas reafirmam as transversalidades dos marcadores de classe, raça e gênero nas histórias destas mulheres, e a necessidade de que os serviços de saúde fomentem estratégias de escuta, vínculos e suporte para a atenção à saúde física e mental deste perfil de usuárias, na perspectiva da integralidade do cuidado. 
Palavras-chave: Violência Sexual; Imagem Corporal; Psicologia.
Material Optimization, Reverse Engineering and Rapid Prototyping of a Handmade Shaver
Authors: Echeverria Tamayo Francisco Javier , Amancha Proaño Pablo Israel , Miranda Salazar María Soledad
Published: June 2024

This study investigates the optimization of materials for a hand-crafted razor using innovative additive manufacturing techniques. It reviews previous patent designs to avoid replicating existing ones. Subsequently, a preliminary razor drawing was created based on hand biomechanics to determine compatible hand grips. This process culminated in a functional prototype, digitally rendered using a FARO Edge E09-05-17-32364 scanner supported by point cloud data. Various ComputerAided Design (CAD) software’s were utilized to generate a digital model saved in an STL file format. Employing Fused Deposition Modeling (FDM) with ABS and PLA, alongside Stereo-lithography/Digital Light Processing (SLA/DLP) with resin technologies, the final prototype was produced, achieving a 45% material optimization in the handle. Additionally, gripping system for the razor blade was designed at the shaver’s tip, ensuring secure closure a satisfactory performance.
Optimizing Iron, Manganese, and Zinc Fertilization in Rice (Oryza sativa L.) Through Bacillus, Pseudomonas, and Azospirillum bacteria
Authors: Barahona Pico Yenny Astrid , Ortiz Paz Rocío Alexandra , López Rayo Sandra
Published: June 2024

Rice (Oryza sativa), is a cereal crop crucial for global food security. The limited availability of the micronutrients iron (Fe), manganese (Mn), and zinc (Zn) in calcareous soils can lead to metabolic disturbances in the plant, which are shown in several anomalies reducing yield and, in severe situations, the plant dead. These three micronutrients can be solubilized through plant growth-promoting microorganisms naturally found in the soil rhizosphere. These microorganisms have been also isolated from soils and used as biostimulants and biofertilizers, facilitating their use to optimize rice cultivation. This literature review describes the nature, assimilation, and significance of the micronutrients Fe, Mn, and Zn in the soil and in rice cultivation. It also investigates the use of more relevant microorganisms Bacillus, Pseudomonas, and Azospirillum as ingredients that promote rice growth and productivity. Furthermore, it discusses their mechanisms: the secretion of the siderophores deoxymugenic acid (DMA) and mugenic acid (MA); the production of organic acids like indole-3-acetic acid (IAA) and abscisic acid; the production of phytohormones (i.e. cytokinins); and a network of metalloproteins that facilitate soil acidification. These mechanisms enable the solubilization of Fe, Mn, and Zn in the soil associated with the crop, making them available for absorption by the root system in the form of chelates. In conclusion, Bacillus, Pseudomonas, and Azospirillum have the potential to enhance plant metabolic processes, alleviating micronutrient deficiencies and mitigating adverse environmental impacts.
Prediction Of The Remaining Useful Life Of Lithium-Ion Batteries Based On An Empirical Mode Approach With Artificial Neural Networks
Authors: Bayrı Ozancan , Akkaya Sıtkı
Published: June 2024

Forecasting future capacities and estimating the remaining useful life, while incorporating uncertainty quantification, poses a crucial yet formidable challenge in the realm of battery health diagnosis and management. In this study, a data-driven model based on artificial neural networks (ANN) and signal decomposition techniques including Empirical Mode Decomposition (EMD), Ensemble Empirical Mode Decomposition (EEMD), and Empirical Wavelet Transform (EWT) is presented to predict the capacity value of lithium-ion batteries. Signal decomposition was performed using the discharge voltage values for four different batteries. A total of 22 features were obtained. The features of the signal decomposition methods were evaluated separately as well as hybrid approaches. Mean Squared Error (MSE), Mean Absolute Percentage Error (MAPE) and Root Mean Square Error (RMSE) performance metrics are used in the proposed method and the values obtained are 3.67×10-6, 0.001351 and 0.002311, respectively. According to the findings, the hybrid model proposed demonstrated positive results in terms of accuracy, adaptability, and robustness.
Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization
Authors: Vardar Özge , Mehmetoğlu Al Ayça , Yıldırım Yeliz
Published: June 2024

Cafestol (CFS) is present in unfiltered coffee types and exhibits antidiabetic, anti-inflammatory and anticarcinogenic properties. The ionic gelation method was used to synthesise CFS-loaded chitosan (CS), and alginate (ALG) nanoparticles with high loading efficiency. The characterization, thermal properties and surface morphology of CFS-loaded biopolymer nanoparticles were carried out by FTIR, TGA and SEM, respectively. The encapsulation efficiency of the synthesised CFS-loaded biopolymer nanoparticles was found to be as 53% (CFS-loaded ALGNPs) and 92% (CFS-loaded CSNPs) by high-pressure liquid chromatography. The particle sizes determined using Malvern Zeta Sizer Ultra were 97 ± 4.04 (CFS-loaded CSNPs) and 81 ± 6.51 (CFS-loaded ALGNPs).
educación con justicia social: aulas comunitarias dialógicas en Chile
Authors: Ferrada Donatila , Del Pino Miguel , Astorga Blanca , Dávila Gianina , Bastías Cecilia
Published: June 2024

La justicia social es un tema relevante en la sociedad chilena actual, en particular para las experiencias de aulas comunitarias que son el núcleo de esta investigación. Las aulas dialógicas tienen como propósito revertir las injusticias en el sistema educativo formal chileno. El presente estudio, realizado durante cuatro años en ocho aulas comunitarias distribuidas a lo largo del país, busca, mediante la investigación participativa, conocer si hay avances en justicia social de reconocimiento recíproco y paridad participativa. Los hallazgos revelan notorios progresos en las relaciones sociales entre personas de la comunidad y de la escuela, y en cambios estructurales que impactan el currículo.
Evolving paradigms in the diagnosis and management of premenopausal women with abnormal uterine bleeding
Authors: Yılmaz Aksoy Mine Senem , Bornaun Teymur
Published: June 2024

Abnormal uterine bleeding (AUB) is a common gynecological complaint among premenopausal women, encompassing a wide range of underlying disorders that complicate diagnosis and management. The evolving paradigms in medical science now incorporate advanced imaging techniques, personalized medicine, and molecular diagnostics to improve the accuracy of diagnoses and the effectiveness of treatment plans. This review examines recent advancements in the diagnostic approach, including the use of transvaginal ultrasonography, hysteroscopy, and biomarker analysis, which have significantly refined the identification of endometrial pathologies. Furthermore, we discuss the shift towards individualized treatment strategies that consider patient-specific factors such as age, reproductive plans, and comorbidities, facilitating tailored therapies. Special attention is given to the role of medical therapies ranging from hormonal treatments to novel non-hormonal drugs, as well as the consideration of minimally invasive surgical options as part of a comprehensive management strategy. By integrating current research findings with clinical practice guidelines, this article aims to provide a synthesized view of the dynamic field of AUB management, proposing a multidisciplinary approach to enhance patient outcomes in premenopausal women.
Enhancing Technology Competence among Primary Students through STEAM Lessons Applying the Design Thinking Process
Authors: Nguyen Hoai-Nam , Nguyen Hong-Duong , Ta Thanh-Trung Ta
Published: June 2024

This study seeks to evaluate the impact of integrating elements of arts and humanities education into the topic of STEAM on the formation and development of students’ competence. The paper suggests a procedure for teaching STEAM subjects using design thinking approaches. Then, technology-related lessons were covered in practical pedagogical activities for grade 3 pupils at three primary schools in Hai Phong, Vietnam. The findings demonstrate that the suggested STEAM subject teaching methodology is workable and helps students develop eight distinctive behavioural markers of technical competence. As a result, this study offers primary school instructors a strategy for implementing STEAM instruction.
Motor efficiency in Relation to Body Weight Status and Gender in Preschool Children
Authors: Muhič Miran
Published: June 2024

Deficits in motor skills and function are associated with overweight and obesity in children. This study aimed to investigate the development of motor efficiency in 3-4-year-old children over seven months and to identify possible gender and body weight status differences in motor efficiency. In the study, there were 45 children (21 girls, 24 boys), the mean age of whom was 39 months. Analysis of the results of testing for differences in motor efficiency according to body weight status and movement components showed no statistically significant differences (p>0.05) between healthy weight and overweight children.
Besedni red veznika: slovarski in skladenjski pogled
Authors: Gabrovšek Dejan
Published: June 2024

Veznik stoji na vezniškem mestu, to je začetno mesto oziroma ničto v stavku, ki ga uvaja. Na tem mestu lahko stojijo vsi vezniki. Primeri, v katerih veznik ne stoji na prvem mestu, se delijo na zaimke, ki so del besedne zveze, ki kot celota stoji na prvem mestu in s tem deluje vezniško, na možnost členka, veznika ali prislova, ki modificira celotni podredni stavek, pred katerim stoji, in na stilistično zaznamovane enote. Besedni red veznika je pomemben pri raziskovanju, katera besedna vrsta posamezne besede je prvotna.
Ustrój Republiki Weneckiej oczami polskich podróżników na przełomie XVIII i XIX wieku
Authors: Paszek Weronika
Published: June 2024

Artykuł przedstawia postrzeganie ustroju Republiki Weneckiej przez polskich podróżników na przełomie XVIII i XIX w. W relacjach z podróży peregrynanci opisywali poszczególne organy władzy, często porównując je z ich odpowiednikami na ziemiach polskich, bądź wyrażali chęć wprowadzenia podobnych rozwiązań w Rzeczypospolitej Obojga Narodów. Opisywano także zachowania szlachty oraz doszukiwano się przyczyn słabnącej potęgi miasta i upadku Republiki Weneckiej, co także wielokrotnie nawiązywało do sytuacji w ojczyźnie pamiętnikarzy.
Molecular Characterization and Phylogenetic Analysis of CPV-2 from Diarrheic Dogs in and Around Nagpur
Authors: Dhas V.A. , Warke S.R. , Ingle S.A. , Tikoo Mehak
Published: June 2024

Background: Canine Parvovirus (CPV) is a major viral infection that results in acute hemorrhagic gastroenteritis and myocarditis in puppies aged 3-4 months. Despite successful vaccination, it produces significant morbidity and mortality. Inadequate immunity and current kennel practices such as early weaning have predisposed the young canines to CPV. The present study aimed to characterize different antigenic types of CPV-2 in Nagpur region. Methods: In the current investigation, 50 fecal samples were obtained from dogs suspected of having CPV-2 from 2020-2023 in Nagpur, India and subjected to various detection tests such as haemagglutination test, polymerase chain reaction (PCR), Nested PCR (NPCR) followed by VP2 gene sequencing and phylogenetic analysis. Result: A total of 9 (18%) of the 50 samples tested positive for the haemagglutination test, while 19 (38%) and 29 (58%) tested positive for conventional PCR and NPCR. NPCR was found to be the most sensitive detection tool of all of them. Sequence analysis found 99.85%-100% similarity with CPV-2b and 2c antigenic type sequences from China and 99.79% identity with sequences from Mizoram state of India. CPV-2b and CPV-2c were the major antigenic types circulating in Nagpur, India. This study will help us to understand the circulating antigenic types of CPV-2 in Nagpur region and promote the formulation of novel diagnostics and vaccines.
Sistemas de ventilación automatizados para el control de la calidad del aire en industrias y áreas de trabajo que involucren alimentos
Authors: Castillo Picado Gerald , Sanabria Salas Johel
Published: June 2024

Los sistemas de control automatizado de aire son una tecnología avanzada que permite a las industrias gestionar y controlar la calidad del aire en su entorno. Estos sistemas utilizan una combinación de sensores, controladores y software inteligente para tomar decisiones de manera automática. Su capacidad para medir la calidad del aire, la humedad, la temperatura y la presencia de insectos es especialmente útil en entornos industriales que pueden ser pesados para los trabajadores debido a factores ambientales, entre las ventajas que ofrecen estos sistemas se encuentran la mejora de la salud, la comodidad y la seguridad de los trabajadores. La automatización de estas funciones también reduce los costos de energía y aumenta la eficiencia de los procesos de producción. Además, estos sistemas pueden ser personalizados para adaptarse a las necesidades específicas de cada industria, lo que es fundamental para el buen desarrollo del proceso de salud, ambiental y de confort.
The Gratitude and Happiness of A Mother with A Child in Special Need
Authors: Ulfasari Retty , Trimulyaningsih Nita
Published: June 2024

This study aimed to investigate the relationship between gratitude and happiness in mothers of exceptional children. The research hypothesis in this study was a positive relationship between gratitude and happiness in mothers of exceptional children. The participants in this study were 65 mothers of exceptional children aged 18 - 60 years. This study used two scales, namely the happiness scale translated by Ramadhonna (2017), referring to The Subjective Happiness Scale (SHS) developed by Lyubomirsky and Lepper (1999). The gratitude scale, adapted from Surya (2016), refers to the aspect of the gratitude scale proposed by Al-Jauziyah (1998). The Pearson product-moment correlation coefficient was used to analyze the data in this study. The results of the data analysis showed that r = 0,520 with the significance p = 0,000 (p <0,05). The determination analysis (r2) showed that gratitude contributes 27% to the happiness of mothers of special needs children. Thus, it can be concluded that the hypothesis proposed in this study was accepted. The researcher also conducted additional analyses based on the demographic data, and then the discussions on the findings will be discussed further. Gratitude is highly recommended in interventions to increase happiness or well-being.
The Dream Vision and Medieval Incubation in the Hypnerotomachia P. Epistemological Reflections on the Dream in Literature
Authors: Piña Rubio Liza Nereyda
Published: June 2024

Attributed to Francesco Colonna, the Hypnerotomachia Poliphili (HP) —The Strife of Love in a Dream— wrote in the Renaissance’s threshold: 1499. From our perspective, in spite of the date of its publication, it is a novel deeply rooted in the medieval tradition which, in turn, was nourished of Patristic Literature sources. In consequence, will be demonstrated that Colonna adopted, in a one hand, the Christian dream vision perspective (the medieval dream-book and incubation), to access the knowledge of the [him]self. In another hand, monastic composing strategies —about prayer and spiritual healing— were adopted, by the author, as a cognitive tool intended for reflection the imaginary creation process. The present research aims to demonstrate that hp is a monastic and literary exercise with redeeming goals. For this reason, will apply the medieval taxonomy of dream-visions. We will expose like pieces ofevidence certain passages from the HP and determined iconographic materials. The selected contents express medieval dream-vision concerns, metacognitive reflections of the author about literary practice, and his epistemological approaching about the meaning of the dreambooks like cultural devices.