bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantification of Precipitation and Evapotranspiration Uncertainty in Rainfall-Runoff Modeling
Authors: Baig Faisal , Sherif Mohsen , Faiz Muhammad Abrar
Published: March 2022

Mountainous watersheds have always been a challenge for modelers due to large variability and insufficient ground observations, which cause forcing data, model structure, and parameter uncertainty. This study employed Differential Evolution Adaptive Metropolis (DREAM) algorithm which utilizes Markov Chain Monte Carlo (MCMC) approach to account for forcing data uncertainty. A conceptual degree day snowmelt model, MIKE 11 NAM (Nedbor Afstromnings Model), was used to simulate snowmelt runoff from Ilgaz basin, with an area of 28.4 km2 area, located in the northern part of Turkey. The mean elevation is around 1700 m and the basin is covered with broadleaf forest and has mainly brown soil with a high water holding capacity. Precipitation and evapotranspiration (ET) values were optimized in combination with model parameters conditioned on observed discharges and corrected values of input data were utilized for calibration and validation. Results showed that the observed precipitation was over-estimated by almost 10%, while evapotranspiration calculated by Penman–Monteith method was underestimated. The mean values of storm and ET multipliers were obtained as 1.14 and 0.84, respectively. When only parameter uncertainty was considered, calibration did not yield Nash–Sutcliffe Efficiency (NSE) greater than 0.64. However, when forcing data uncertainty was incorporated in the DREAM approach, an improved value of NSE (0.84) was obtained. After calibration and treatment of forcing data errors, the model yielded reasonable prediction uncertainty bounds and well-defined posterior distributions of NAM model parameters. Main objectives of the study are to assess the applicability of MIKE 11 NAM model to the selected catchment. In addition, the importance of errors in the input forcing variables to the model is demonstrated.
Usefulness of Smartphones in Dermatology: A US-Based Review
Authors: Ouellette Samantha , Rao Babar K.
Published: March 2022

(1) Background: As smartphones have become more widely used, they have become an appealing tool for health-related functions. For dermatology alone, hundreds of applications (apps) are available to download for both patients and providers. (2) Methods: The Google Play Store and Apple App Store were searched from the United States using dermatology-related terms. Apps were categorized based on description, and the number of reviews, download cost, target audience, and use of AI were recorded. The top apps from each category by number of reviews were reported. Additionally, literature on the benefits and limitations of using smartphones for dermatology were reviewed. (3) Results: A total of 632 apps were included in the study: 395 (62.5%) were marketed towards patients, 203 (32.1%) towards providers, and 34 (5.4%) towards both; 265 (41.9%) were available only on the Google Play Store, 146 (23.1%) only on the Apple App Store, and 221 (35.0%) were available on both; and 595 (94.1%) were free to download and 37 (5.9%) had a cost to download, ranging from USD 0.99 to USD 349.99 (median USD 37.49). A total of 99 apps (15.7%) reported the use of artificial intelligence. (4) Conclusions: Although there are many benefits of using smartphones for dermatology, lack of regulation and high-quality evidence supporting the efficacy and accuracy of apps hinders their potential.
Exploring the Determinants of Nascent Social Entrepreneurial Behaviour
Authors: Ip Ching Yin , Zhuge Tingna , Chang Yu Shan , Huang Ting-Huei , Chen Yin-Lin
Published: March 2022

Following the emergence of social, environmental, and public health issues, this study analysed the determinants of nascent social entrepreneurial behaviour. This research investigated the effects of empathy and prior experience with social problems on nascent social entrepreneurial behaviour through social entrepreneurial self-efficacy, outcome expectations of social entrepreneurship, and perceived social support. Through utilising the quantitative survey method, this study gathered a total of 560 valid responses, comprising 258 Chinese respondents and 302 Taiwanese respondents. Outcome expectations and perceived social support positively influenced nascent social entrepreneurial behaviour for the Chinese sample, whereas social entrepreneurial self-efficacy and perceived social support positively influenced nascent social entrepreneurial behaviour for the Taiwanese sample. This research enriches the existing literature by taking account of social entrepreneurial behaviour, instead of merely analysing social entrepreneurial intentions.
Using a Novel Functional Brain Network Approach to Locate Important Nodes for Working Memory Tasks
Authors: Ding Weiwei , Zhang Yuhong , Huang Liya
Published: March 2022

Working Memory (WM) is a short-term memory for processing and storing information. When investigating WM mechanisms using Electroencephalogram (EEG), its rhythmic synchronization properties inevitably become one of the focal features. To further leverage these features for better improve WM task performance, this paper uses a novel algorithm: Weight K-order propagation number (WKPN) to locate important brain nodes and their coupling characteristic in different frequency bands while subjects are proceeding French word retaining tasks, which is an intriguing but original experiment paradigm. Based on this approach, we investigated the node importance of PLV brain networks under different memory loads and found that the connectivity between frontal and parieto-occipital lobes in theta and beta frequency bands enhanced with increasing memory load. We used the node importance of the brain network as a feature vector of the SVM to classify different memory load states, and the highest classification accuracy of 95% is obtained in the beta band. Compared to the Weight degree centrality (WDC) and Weight Page Rank (WPR) algorithm, the SVM with the node importance of the brain network as the feature vector calculated by the WKPN algorithm has higher classification accuracy and shorter running time. It is concluded that the algorithm can effectively spot active central hubs so that researchers can later put more energy to study these areas where active hubs lie in such as placing Transcranial alternating current stimulation (tACS).
Distribution, Genesis, and Human Health Risks of Groundwater Heavy Metals Impacted by the Typical Setting of Songnen Plain of NE China
Authors: Zhai Yuanzheng , Zheng Fuxin , Li Dongfan , Cao Xinyi , Teng Yanguo
Published: March 2022

Heavy metals pollution in groundwater and the resulting health risks have always been an environmental research hotspot. However, the available information regarding this topic and associated methods is still limited. This study collected 98 groundwater samples from a typical agricultural area of Songnen Plain in different seasons. The pollution status and sources of ten heavy metals (As, Ba, Cd, Co, Cr (VI), Cu, Fe, Mn, Ni, Pb, and Zn) were then analyzed and compared. In addition, the human health risks assessment (HHRA) model was used to calculate human health risks caused by heavy metals in groundwater. The results revealed that heavy metals were mainly distributed in the northwest of the study area and along the upper reaches of the Lalin river and that the concentrations of heavy metals were higher during the wet season than the dry season. Industrial and agricultural activities and natural leaching are the main sources, and each kind of heavy metal may have different sources. Fe and Mn are the primary pollutants, mainly caused by the native environment and agricultural activities. The exceeding standard rates are 71.74% and 61.54%, respectively based on the Class III of Quality Standard for Groundwater of China (GB/T 14848-2017). The maximum exceeding multiple are 91.45 and 32.05, respectively. The health risks of heavy metals borne by different groups of people were as follows: child > elder > young > adult. Carcinogenic heavy metals contribute to the main risks, and the largest risks sources are Cr and As. Therefore, the government should appropriately restrict the use of pesticides and fertilizers, strictly manage the discharge of enterprises, and control man-made heavy metals from the source. In addition, centralized water supply and treatment facilities shall be established to prevent the harm of native heavy metals.
Serious Leisure and Passion in University Programs for Seniors
Authors: Doistua Joseba , Lazcano Idurre , Madariaga Aurora
Published: March 2022

Perseverance and persistence, effort, leisure career, permanent acquisitions, specific norms, and identification with the occupation are some of the hallmarks of the serious leisure perspective. The Dualistic Model of Passion (DMP) understands passion as a strong inclination towards an activity that a person loves, considers important, and in which they invest a great amount of time and energy. This article proposes to explore these two theoretical constructs that converge in their conceptual bases, in a group of older people who regularly participate in university training programs throughout life. The sample is made up of 157 persons over 60 years old enrolled in courses for the elderly at the University of Deusto (Bilbao, Spain). The quantitative findings revealed: (1) that there are no significant differences according to sociodemographic variables, (2) that learning throughout life in the case of older people can be converted into serious leisure, and (3) that the participants in training programs for seniors develop a harmonious passion for such activity.
Investigation of Differences in Allostatic Load among Black Men by Level of Educational Attainment: High School Graduates Experience the Highest Levels of Stress
Authors: Rogers Charles R. , Moore Justin X. , Gilmore Danielle R. , Petersen Ethan , Brooks Ellen , Kennedy Carson , Thorpe Roland J.
Published: March 2022

Allostatic load (AL)—the biological assessment of long-term exposure to stress—may explain mortality-rate disparities among non-Hispanic Black (Black) men. We aimed to investigate AL among Black men with equivalent education status after controlling for income. A cross-sectional study was employed to investigate AL among 4113 Black men who participated in the National Health and Nutrition Examination Survey between 1999–2018. A summation of 8 biomarker factors were used to compute AL, differences in socio-demographic characteristics by education status were evaluated, and health behaviors that may influence AL were examined. To determine the high-risk thresholds for each AL component, we examined each component’s distribution among NHB men for whom complete biomarker data were available in the NHANES sample. High-risk thresholds were determined as either (1) above the 75th percentile for body mass index (BMI), diastolic blood pressure (DBP), glycated hemoglobin, systolic blood pressure (SBP), total cholesterol, and serum triglycerides; or (2) below the 25th percentile for serum albumin and serum creatinine. Modified Poisson regression models were used to estimate prevalence ratios and their associated 95% confidence intervals for high AL risk while adjusting for potential confounders. Black men with a high school diploma/GED had a greater prevalence of high AL compared with Black men who had other levels of education, and a slightly higher prevalence of high AL compared with Black men who had less than a high school education. Black men with college degrees had a lower prevalence of high AL than Black men with the lowest levels of educational attainment. Researchers must further examine the hidden costs stemming from the interplay between discrimination associated with being Black in America and systemic racism in the educational system—which may be preventing Black men from achieving optimal health.
Couple’s Relationship and Depressive Symptoms during the Transition to Parenthood and Toddler’s Emotional and Behavioral Problems
Authors: Pinto Tiago Miguel , Figueiredo Bárbara
Published: March 2022

The couple’s relationship and mother and father’s depressive symptoms during the transition to parenthood were associated with the toddler’s emotional and behavioral problems. This study aimed to analyze how the couple’s positive and negative interactions and mother and father’s depressive symptoms during the transition to parenthood impact toddlers’ emotional and behavioral problems. A sample of 95 mothers and fathers (N = 190) were recruited and individually completed questionnaires to assess couples’ positive and negative interactions and depressive symptoms during the first trimester of pregnancy and at 3 and 30 months postpartum, and they completed the Child Behavior Checklist 1.5–5 at 30 months postpartum. The path analyses revealed that the couple’s postnatal negative interaction partially mediates the impact of the mother’s prenatal depressive symptoms on the toddler’s internalizing problems at 30 months postpartum. The father’s postnatal depressive symptoms and the couple’s concurrent positive interaction mediated the impact of the couple’s prenatal positive interaction on the toddler’s externalizing problems at 30 months postpartum. The screening of the couple’s negative interaction and depressive symptoms during pregnancy and the postnatal period can help to identify mothers, fathers, and toddlers at risk for mental health problems.
Second Victims in Intensive Care—Emotional Stress and Traumatization of Intensive Care Nurses in Western Austria after Adverse Events during the Treatment of Patients
Authors: Ganahl Samuel , Knaus Mario , Wiesenhuetter Isabell , Klemm Victoria , Jabinger Eva M. , Strametz Reinhard
Published: March 2022

Background: The second victim phenomenon is common among nurses in intensive care units. Apart from quantitative studies, little is known about individual cases among those high-risk groups. This study evaluates the natural history and cause of second victim traumatization in Western Austria for the first time to tailor specific intervention. Methods: A total of 20 guided interviews were conducted with intensive care nurses in Western Austria. All interviews were transcribed and analyzed with MAXQDA software. Evaluation followed the structuring qualitative content analysis scheme according to Kuckartz. Results: The most frequent symptoms of the second victim phenomenon reported were feelings of guilt and problems with falling asleep. Coping with the second victim phenomenon was accomplished by conversations in private as well as among work colleagues. Conclusions: Intensive care nurses are exposed to many exceptional situations which have a high likelihood of resulting in second victim traumatization. As proximal psychosocial support is considered to be a main source of coping, wide-spread implementation of effective psychosocial peer support programs ought to be applied by medical organizations. Patient safety measures such as proactive and reactive clinical risk management (e.g., CIRS) should be linked to second victim support.
Overcoming the “Dark Side” of Technology—A Scoping Review on Preventing and Coping with Work-Related Technostress
Authors: Rohwer Elisabeth , Flöther Joelle-Cathrin , Harth Volker , Mache Stefanie
Published: March 2022

In the course of the digitalisation of work, the phenomenon of technostress is increasingly being examined. While there is a plethora of research on its causes and consequences, a growing body of research on mitigating work-related technostress is emerging. In order to identify opportunities to overcome this “dark side” of technology, this scoping review aims to provide a comprehensive overview of the current state of research on how to prevent and cope with work-related technostress. The databases PubMed, MEDLINE, PsycInfo, PSYNDEX, and Web of Science were searched in the time period between 2008 and 2021. The studies were screened independently by two authors and selected based on predefined inclusion and exclusion criteria. Sixty-two studies were included and their methodological quality was assessed using standardised checklists. Resources were identified at the technical, organisational, social and personal level, including, e.g., leadership, organisational and technical support as well as self-efficacy and IT mindfulness. Problem- and emotion-focused coping strategies were, e.g., seeking support or distancing from IT. None of the included studies investigated prevention measures, emphasising a dearth of research that needs to be addressed in the future. Nevertheless, the identified resources and coping strategies provide starting points to address adverse work- and health-related consequences and reduce work-related technostress.
Influence of Diagnostic Delay on Survival Rates for Patients with Colorectal Cancer
Authors: Padilla-Ruiz María , Morales-Suárez-Varela María , Rivas-Ruiz Francisco , Alcaide Julia , Varela-Moreno Esperanza , Zarcos-Pedrinaci Irene , Téllez Teresa , Fernández-de Larrea-Baz Nerea , Baré Marisa , Bilbao Amaia , Sarasqueta Cristina , Aguirre-Larracoechea Urko , Quintana José María , Redondo Maximino ,   on behalf of CARESS-CCR Study Group
Published: March 2022

Colorectal cancer affects men and women alike. Sometimes, due to clinical-pathological factors, the absence of symptoms or the failure to conduct screening tests, its diagnosis may be delayed. However, it has not been conclusively shown that such a delay, especially when attributable to the health system, affects survival. The aim of the present study is to evaluate the overall survival rate of patients with a delayed diagnosis of colorectal cancer. This observational, prospective, multicenter study was conducted at 22 public hospitals located in nine Spanish provinces. For this analysis, 1688 patients with complete information in essential variables were included. The association between diagnostic delay and overall survival at five years, stratified according to tumor location, was estimated by the Kaplan–Meier method. Hazard ratios for this association were estimated using multivariable Cox regression models. The diagnostic delay ≥ 30 days was presented in 944 patients. The presence of a diagnostic delay of more than 30 days was not associated with a worse prognosis, contrary to a delay of less than 30 days (HR: 0.76, 0.64–0.90). In the multivariate analysis, a short delay maintained its predictive value (HR: 0.80, 0.66–0.98) regardless of age, BMI, Charlson index or TNM stage. A diagnostic delay of less than 30 days is an independent factor for short survival in patients with CRC. This association may arise because the clinical management of tumors with severe clinical characteristics and with a poorer prognosis are generally conducted more quickly.
Consumers’ Intention to Bring a Reusable Bag for Shopping in China: Extending the Theory of Planned Behavior
Authors: Wang Bairong , Li Yong
Published: March 2022

Bringing a reusable bag for shopping is a typical pro-environmental behavior and has been shown to be effective in reducing plastics, but research regarding this green behavior is limited. In this regard, using the snowball sampling technique, this study conducts a survey on a sample of 361 Chinese consumers to investigate their intention to bring a reusable bag for shopping based on the theory of planned behavior. To increase the explaining power for behavioral intention, this study extended the TPB by adding two additional variables: locus of control and environmental concern. Data was analyzed using the structural equation modeling technique. Results show that attitude, perceived behavioral control, and subjective norm exert significant and positive influence on consumers’ intention to bring reusable bags for shopping, and the perceived behavioral control exerts the greatest influence, followed by attitude and subjective norm. Both locus of control and environmental concern fail to directly impact consumers’ bringing intention, but they could impact consumers’ intention indirectly. Specifically, the external locus of control exerts a negative influence on attitude and perceived behavioral control. Environmental concern positively impacts consumers’ attitudes towards bringing reusable bags for shopping. Results of this study could provide valuable insights into plastics management and policy design to promote consumers’ green shopping behaviors. For instance, the finding that perceived behavioral control is the greatest contributor to consumers’ intention to bring reusable bags highlights the importance of clearing reusable bag preparation and use barriers.
Surface Functionalization of Non-Woven Fabrics Using a Novel Silica-Resin Coating Technology: Antiviral Treatment of Non-Woven Fabric Filters in Surgical Masks
Authors: Tsutsumi-Arai Chiaki , Iwamiya Yoko , Hoshino Reiko , Terada-Ito Chika , Sejima Shunsuke , Akutsu-Suyama Kazuhiro , Shibayama Mitsuhiro , Hiroi Zenji , Tokuyama-Toda Reiko , Iwamiya Ryugo , Ijichi Kouhei , Chiba Toshie , Satomura Kazuhito
Published: March 2022

Masks are effective for preventing the spread of COVID-19 and other respiratory infections. If antimicrobial properties can be applied to the non-woven fabric filters in masks, they can become a more effective countermeasure against human-to-human and environmental infections. We investigated the possibilities of carrying antimicrobial agents on the fiber surfaces of non-woven fabric filters by applying silica-resin coating technology, which can form silica-resin layers on such fabrics at normal temperature and pressure. Scanning electron microscopy and electron probe microanalysis showed that a silica-resin layer was formed on the fiber surface of non-woven fabric filters. Bioassays for coronavirus and quantitative reverse transcription-polymerase chain reactions (RT-PCR) revealed that all antimicrobial agents tested loaded successfully onto non-woven fabric filters without losing their inactivation effects against the human coronavirus (inhibition efficacy: >99.999%). These results indicate that this technology could be used to load a functional substance onto a non-woven fabric filter by vitrifying its surface. Silica-resin coating technology also has the potential of becoming an important breakthrough not only in the prevention of infection but also in various fields, such as prevention of building aging, protection of various cultural properties, the realization of a plastic-free society, and prevention of environmental pollution.
The Impact of Acute Tinnitus on Listening Effort: A Study Based on Clinical Observations of Sudden Sensorineural Hearing Loss Patients
Authors: Huang Chii-Yuan , Li Dian-Sian , Tsai Ming-Hsien , Chen Chih-Hao , Cheng Yen-Fu
Published: March 2022

This study investigates the relationship between listening effort and acute tinnitus over the clinical course of sudden sensorineural hearing loss (SSNHL) before and after treatment. Thirty SSNHL patients with acute tinnitus were enrolled in this prospective study. Each patient was evaluated before treatment and after 1 and 3 months of follow-up. Listening effort was evaluated in the unaffected ears in two conditions (with and without background noise) using a dual-task paradigm, which included a primary (speech recognition) task and a secondary (visual reaction time) task. Tinnitus severity was assessed with the Tinnitus Handicap Inventory (THI). It was observed that background noise significantly increased listening effort in SSNHL patients with acute tinnitus before and after treatment. THI scores and listening effort in quiet conditions (** p = 0.009) were significantly decreased three months after treatment. In an analysis of the relation between tinnitus severity and listening effort, it was found that the THI total score was significantly correlated with listening effort in quiet (* p = 0.0388) and noisy conditions (* p = 0.044) before treatment. We concluded that SSNHL patients with acute tinnitus exerted greater listening effort in the presence of background noise than in quiet conditions. Furthermore, listening effort was reduced as tinnitus improved in SSNHL patients during the three months after treatment. Both before and after 3 months of treatment, patients who were more affected and emotionally distressed by tinnitus tended to exert more listening effort in both quiet and noisy environments.
A Magnetic Field Canceling System Design for Diminishing Electromagnetic Interference to Avoid Environmental Hazard
Authors: Song Yu-Lin , Lin Hung-Yi , Manikandan Saravanan , Chang Luh-Maan
Published: March 2022

Electromagnetic interference is a serious and increasing form of environmental pollution, creating many issues in the areas of health care and industrial manufacturing. The performance of high-precision measurement equipment used in health care and the manufacturing industry is sensitive to electromagnetic interference. However, extremely low-frequency magnetic fields (ELFMF), with a frequency range from 3 to 30 Hz, generated by high-power lines have become the main interference source in high-tech foundries. This paper presents a magnetic cancelling system that works by combining active cancelling technology and passive cancelling technology to reduce the ELFMF around high-precision measurement equipment. The simulation and experimental results show the validity and feasibility of the proposed system.
Association between Cardiorespiratory Fitness and Metabolic Syndrome in Korean Older Adults
Authors: Kim Shinuk
Published: March 2022

Background: Little is known about the relationship between non-exercise-based estimation of cardiorespiratory fitness (eCRF) and metabolic syndrome (MetS) in Korea. The current study examined the prognostic role of eCRF in the risk stratification of MetS in a representative sample of Korean older adults (1822 men and 3069 women). Methods: The data used in the current study were extracted from the Korea National Health and Nutrition Examination Surveys IV and V. eCRF was obtained using a previously validated algorithm. MetS was defined according to the National Cholesterol Education Program definition with the acceptance of a Korean-specific waist circumference cutoff point. Results: Lower eCRF was significantly correlated with abnormalities in several components of MetS, including abdominal obesity, elevated glucose, elevated triglycerides, and decreased high-density lipoprotein cholesterol. Furthermore, there was an inverse linear relationship between MetS prevalence and eCRF levels; higher eCRF was significantly and independently associated with lower prevalence of MetS. Conclusion: The current findings suggest that eCRF can be adopted as a prognostic measure in determining the risk for MetS for elderly persons.
Selection Process for Romanian Children in Handball Based on Coordinative Abilities: A Questionnaire Survey
Authors: Petrariu Ileana , Leuciuc Florin Valentin
Published: March 2022

According to the reviewed literature, the selection system in handball is quite complex and requires new approaches from trainers based on the current and modern requirements of this game. This paper investigated the importance of coordinative ability development in handball in the selection process for young Romanian children (10–12 years old). The results were obtained from a sociological questionnaire survey, for which 109 handball coaches, 34 female and 75 male, were questioned. The mean age was 40.71 years (SD = ±5.32) with a range of 31–51 years for female coaches and 40.3 years (SD = ±7.53) with a range of 30–62 years for male coaches. Their experience in handball coaching varied from 10 to 30 years, with 19.88 (SD = ±5.05) years of experience on average for female coaches and 19.09 (SD = ±5.26) years of experience on average for male coaches. The answers delivered depended on the experience and knowledge the coaches had and difficulties they had encountered over the years. Data are presented using a variety of appropriate descriptive statistics, including frequencies, percentages, and mean and standard variation. Obtained data were modeled using a one-way analysis of variation (ANOVA). The questionnaire format was three-to-five-point Likert scale. As a general overview, in the opinion of the surveyed specialists, the Romania selection process for handball does not meet their expectations, and the development level of coordinative abilities in 10–12 year-old children is medium to weak. A total of 61.76% female and 58.66% male coaches stressed the importance of developing coordination abilities to optimize the selection process of children for handball games, opening up a new approach in modern training methods for performance achievement. The obtained results from this paper questionnaire can be used by coaches as a different approach to the handball training process, considering that handball is a game mainly based on coordination.
‘It All Kind of Links Really’: Young People’s Perspectives on the Relationship between Socioeconomic Circumstances and Health
Authors: Fairbrother Hannah , Woodrow Nicholas , Crowder Mary , Holding Eleanor , Griffin Naomi , Er Vanessa , Dodd-Reynolds Caroline , Egan Matt , Lock Karen , Scott Steph , Summerbell Carolyn , McKeown Rachael , Rigby Emma , Kyle Phillippa , Goyder Elizabeth
Published: March 2022

Meaningful inclusion of young people’s perceptions and experiences of inequalities is argued to be critical in the development of pro-equity policies. Our study explored young people’s perceptions of what influences their opportunities to be healthy within their local area and their understandings of health inequalities. Three interlinked qualitative focus group discussions, each lasting 90 to 100 min, with the same six groups of young people (n = 42) aged 13–21, were conducted between February and June 2021. Participants were recruited from six youth groups in areas of high deprivation across three geographical locations in England (South Yorkshire, the North East and London). Our study demonstrates that young people understand that health inequalities are generated by social determinants of health, which in turn influence behaviours. They highlight a complex interweaving of pathways between social determinants and health outcomes. However, they do not tend to think in terms of the social determinants and their distribution as resulting from the power and influence of those who create and benefit from health and social inequalities. An informed understanding of the causes of health inequalities, influenced by their own unique generational experiences, is important to help young people contribute to the development of pro-equity policies of the future.
Validation of a Questionnaire of Food Education Content on School Catering Websites in Spain
Authors: Rico-Sapena Nuria , Galiana-Sánchez María , Moncho Joaquín
Published: March 2022

The aim of this study was to design and validate a questionnaire on quality and food education on catering company websites. For the validation of the questionnaire, its reliability, feasibility and content validity characteristics were determined. For content validity, a panel of experts was used and the overall and item-wise Content Validity Index (CVI) of the experts’ responses was calculated. Reliability was determined by the inter-judge agreement method with the analysis of 30 websites using the intraclass correlation coefficient (ICC) and the Bland and Altman plot. Adequate content validity was verified by obtaining a very high CVI (above 0.80) in the analysis of the expert panel’s responses and excellent inter-observer agreement with a very high global ICC (above 0.90) value in the determination of test-retest reliability. The questionnaire is a valid instrument for the evaluation of the quality of school catering websites and their content in food education, as it has good feasibility, high content validity and excellent reliability.
Autogenous Tooth Bone Grafts for Repair and Regeneration of Maxillofacial Defects: A Narrative Review
Authors: Janjua Omer Sefvan , Qureshi Sana Mehmood , Shaikh Muhammad Saad , Alnazzawi Ahmad , Rodriguez-Lozano Francisco J. , Pecci-Lloret Maria Pilar , Zafar Muhammad Sohail
Published: March 2022

Autogenous tooth graft is an innovative and ingenious technique that employs a stepwise approach and utilizes human teeth as an autogenous source of bone graft. The structure of teeth closely resembles bone, both physically and biochemically, and can be efficiently used for the process as it depicts properties of osteoinduction and osteoconduction. Autogenous tooth bone has characteristics similar to bone grafts in terms of healing potential, physical properties, and clinical outcome. Autogenous tooth graft has shown reasonable promise as a graft material for the regeneration of maxillary and mandibular defects. Autogenous tooth bone graft finds its principal application in sinus and ridge augmentations and for socket preservation before implant placement. Additionally, it can be used successfully for alveolar cleft patients and patients with limited periodontal defects. The overall complication rates reported for autogenous tooth grafts are comparable to other graft sources. However, although long-term results are still underway, it is still recommended as a grafting option for limited defects in the cranio-facial region.
A Shot in the Arm for Vaccination Intention: The Media and the Health Belief Model in Three Chinese Societies
Authors: Liu Ruoheng , Huang Yi-Hui Christine , Sun Jie , Lau Jennifer , Cai Qinxian
Published: March 2022

This large-sample study of three Chinese societies—Mainland China, Taiwan, and Hong Kong—demonstrates the importance of media exposure for people’s vaccination intentions during the COVID-19 pandemic. By employing two constructs (i.e., perceived susceptibility and severity) in the health belief model (HBM), the study identifies significant indirect effects of media exposure on individuals’ vaccination intention in all three Chinese societies. That said, media trust negatively moderated the path from perceived severity to vaccination intention in Mainland China and Taiwan. In these two societies, the higher an individual’s trust in media, the less influence of perceived severity on his/her vaccination intention. It suggests that the level of trust in media is a contextual factor in explaining individuals’ decision-making on health issues. Generally, the combination of the HBM and media trust has been proven to be useful for understanding individuals’ vaccination intentions. These findings provide practical considerations for governmental agencies, public institutions, and health campaign designers to promote vaccination in the pandemic.
Empirical Modeling of COVID-19 Evolution with High/Direct Impact on Public Health and Risk Assessment
Authors: Ouerfelli Noureddine , Vrinceanu Narcisa , Coman Diana , Cioca Adriana Lavinia
Published: March 2022

This report develops a conceivable mathematical model for the transmission and spread of COVID-19 in Romania. Understanding the early spread dynamics of the infection and evaluating the effectiveness of control measures in the first wave of infection is crucial for assessing and evaluating the potential for sustained transmission occurring in the second wave. The main aim of the study was to emphasize the impact of control measures and the rate of case detection in slowing the spread of the disease. Non pharmaceutical control interventions include government actions, public reactions, and other measures. The methodology consists of an empirical model, taking into consideration the generic framework of the Stockholm Environment Institute (SEI) Epidemic–Macroeconomic Model, and incorporates the effect of interventions through a multivalued parameter, a stepwise constant varying during different phases of the interventions designed to capture their impact on the model. The model is mathematically consistent and presents various simulation results using best-estimated parameter values. The model can be easily updated later in response to real-world alterations, for example, the easing of restrictions. We hope that our simulation results may guide local authorities to make timely, correct decisions for public health and risk assessment.
Sentinel Lymph Node Biopsy in Surgical Staging for High-Risk Groups of Endometrial Carcinoma Patients
Authors: Raffone Antonio , Raimondo Diego , Travaglino Antonio , Rovero Giulia , Maletta Manuela , Raimondo Ivano , Petrillo Marco , Capobianco Giampiero , Casadio Paolo , Seracchioli Renato , Mollo Antonio
Published: March 2022

Background: In endometrial carcinoma (EC) patients, sentinel lymph node (SLN) biopsy has shown the potential to reduce post-operative morbidity and long-term complications, and to improve the detection of low-volume metastasis through ultrastaging. However, while it has shown high sensitivity and feasibility in low-risk EC patient groups, its role in high-risk groups is still unclear. Aim: To assess the role of SLN biopsy through the cervical injection of indocyanine green (ICG) in high-risk groups of early-stage EC patients. Materials and methods: Seven electronic databases were searched from their inception to February 2021 for studies that allowed data extraction about detection rate and accuracy of SLN biopsy through the cervical injection of ICG in high-risk groups of early-stage EC patients. We calculated pooled sensitivity, false negative (FN) rate, detection rate of SLN per hemipelvis (DRh), detection rate of SLN per patients (DRp), and bilateral detection rate of SLN (DRb), with 95% confidence interval (CI). Results: Five observational cohort studies (three prospective and two retrospective) assessing 578 high risk EC patients were included. SLN biopsy sensitivity in detecting EC metastasis was 0.90 (95% CI: 0.03–0.95). FN rate was 2.8% (95% CI: 0.6–11.6%). DRh was 88.4% (95% CI: 86–90.5%), DRp was 96.6% (95% CI: 94.7–97.8%), and DRb was 80% (95% CI: 75.4–83.9). Conclusion: SLN biopsy through ICG cervical injection may be routinely adopted instead of systematic pelvic and para-aortic lymphadenectomy in surgical staging for high-risk groups of early-stage EC patients, as well as in low-risk groups.
Examining the Relationship between COVID-19 Related Job Stress and Employees’ Turnover Intention with the Moderating Role of Perceived Organizational Support: Evidence from SMEs in China
Authors: Lai Hongshan , Hossin Md Altab , Li Jieyun , Wang Ruping , Hosain Md Sajjad
Published: March 2022

The outbreak of COVID-19 has exerted an enormous impact on society, enterprises, and individuals. It has affected the work attitudes and psychology of employees to a certain extent and their job stress (JS) has also augmented accordingly, leading to increased turnover intention (TI). With the survey responses of 720 employees of small and medium enterprises (SMEs) in China as the sample, we studied the impact of COVID-19 related JS and TI with the moderating effect of perceived organizational support (POS). We utilized linear and multiple regression analysis using Windows SPSS 25. The research findings indicated that the JS caused by COVID-19 in the first affected region (Hubei) was significantly stronger than that in other regions (non-Hubei). JS had a significant positive relationship with employees’ TI, while POS had a significant negative connection with employees’ TI. We also identified that POS weakened the positive association between JS and employees’ TI. These findings are expected to be conducive to and conductive for the upcoming theoretical and empirical investigations as the founding guidelines, as well as for managers in formulating effective policies to curb JS, which would ultimately be helpful in reducing TI.
Mental Well-Being and Job Satisfaction of Hospital Physicians during COVID-19: Relationships with Efficacy Beliefs, Organizational Support, and Organizational Non-Technical Skills
Authors: Capone Vincenza , Borrelli Roberta , Marino Leda , Schettino Giovanni
Published: March 2022

The COVID-19 outbreak has led worldwide governments to take preventive measures to contain the spread of the virus and its extraordinary demands upon healthcare workers. Consequently, healthcare workers have been under high pressures, putting them at risk of developing adverse outcomes. The present study aims to investigate the psychological and organizational factors that contributed to physicians’ well-being during the pandemic. A total of 78 Italian physicians participated in the study. They completed a self-report questionnaire measuring efficacy beliefs, orientation towards patient engagement, job satisfaction, non-technical skills, organizational support, sense of belonging to the hospital, job satisfaction, and mental well-being. Physicians’ sense of belonging to their hospital, efficacy beliefs about their organizations and communication with patients, as well as non-technical skills related to communication and risk awareness were positively associated with job satisfaction. In addition, the latter and sense of belonging to own hospital were positively associated with mental well-being. These findings may guide policymakers and healthcare organizations managers to consider the potential psychosocial factors related to physicians’ well-being and the required preventive measures that can help in enhancing their human and organizational resources to cope with stressful situations such as the COVID-19 pandemic.
Exposure to Antineoplastic Drugs in Occupational Settings: A Systematic Review of Biological Monitoring Data
Authors: Leso Veruscka , Sottani Cristina , Santocono Carolina , Russo Francesco , Grignani Elena , Iavicoli Ivo
Published: March 2022

The high toxicity of antineoplastic drugs (ADs) makes them dangerous not only for patients, but also for exposed workers. Therefore, the aim of this review was to provide an updated overview of the biological monitoring of occupational AD exposure in order to extrapolate information useful to improve risk assessment and management strategies in workplaces. Several studies demonstrated that remarkable portions of healthcare workers may have traces of these substances or their metabolites in biological fluids, although with some conflicting results. Nurses, directly engaged in AD handling, were the occupational category at higher risk of contamination, although, in some cases, personnel not involved in AD-related tasks also showed quantifiable internal doses. Overall, further research carried out on greater sample sizes appears necessary to gain deeper insight into the variability retrieved in the reported results. This may be important to understand the impact of the extent of ADs use, different handling, procedures, and cleaning practices, spill occurrence, training of the workforce, as well as the adoption of adequate collective and personal protective equipment in affecting the occupational exposure levels. This may support the achievement of the greatest clinical efficiency of such therapies while assuring the health and safety of involved workers.
Physical Function in Amateur Athletes with Lumbar Disc Herniation and Chronic Low Back Pain: A Case-Control Study
Authors: Miñambres-Martín Diego , Martín-Casas Patricia , López-de-Uralde-Villanueva Ibai , Fernández-de-las-Peñas César , Valera-Calero Juan Antonio , Plaza-Manzano Gustavo
Published: March 2022

This study aimed to analyze if chronic low back pain (LBP) and lumbar disc herniation induce biomechanics, flexibility, body balance, physical activity, and muscular function alterations compared to a similar asymptomatic cohort. Fifty male volunteers (n = 25 with chronic LBP and lumbar disc herniation and n = 25 pain-free subjects) were enrolled. Range of motion (internal and external hip rotation, ankle dorsiflexion, and active straight leg raise, ASLR), trunk flexibility (finger–floor distance), body balance (Y-balance test) and muscle function (Biering–Sorensen test, prone and lateral bridges) outcomes were assessed. Comparative analyses between sides and group were conducted. Results: Patients showed greater weight and BMI compared with controls (p < 0.05). None of the outcomes bilaterally assessed showed side-to-side differences for pain-free participants (all, p > 0.05) or LBP patients (all, p > 0.05). Regarding the differences between groups, LBP patients showed limited internal hip rotation (p < 0.001), finger–floor distance (p < 0.001), body balance (p < 0.001), and muscle endurance (planks p < 0.001; Biering–Sorensen test p < 0.05). External hip rotation, ASLR, and ankle dorsiflexion range of movement were comparable in both groups (p > 0.05). The sample of pain-free amateur athletes showed greater range of movement for internal hip rotation, lower finger–floor distance, better body balance, and muscle function. However, the external hip rotation, ankle dorsiflexion, and ASLR tests showed no difference between cases and controls.
Population Space–Time Patterns Analysis and Anthropic Pressure Assessment of the Insubric Lakes Using User-Generated Geodata
Authors: Vavassori Alberto , Oxoli Daniele , Brovelli Maria Antonia
Published: March 2022

Human activities are one of the main causes of lake-water pollution and eutrophication. The study of human pressure around lakes is of importance to understand its effects on the lakes natural resources. Social media data is a valuable space–time-resolved information source to detect human dynamics. In this study, user-generated geodata, namely users’ location records provided by the Facebook Data for Good program, are used to assess population patterns and infer the magnitude of anthropic pressure in the areas surrounding the Insubric lakes (Maggiore, Como and Lugano) between Northern Italy and Southern Switzerland. Patterns were investigated across different lakes’ neighbouring areas as well as seasons, days of the week, and day hours in the study period May 2020–August 2021. Two indicators were conceived, computed and mapped to assess the space–time distribution of users around lakes and infer the anthropic pressure. The highest pressure was found around lakes Maggiore and Como coastal areas during weekends in summer (up to +14% average users presence than weekdays in winter), suggesting tourism is the primary accountable reason for the pressure. Contrarily, around lake Lugano, the population dynamic is mostly affected by commuters or weekly workers, where the maximum pressure occurs during weekdays in all seasons (+6.6% average users presence than weekends). Results provide valuable input to further analyses connected, for example, to the correlation between human activities and lake-water quality and/or prediction models for anthropic pressure and tourism fluxes on lakes that are foreseen for the future development of this work.
Synthesis, In Silico, and Biological Evaluation of a Borinic Tryptophan-Derivative That Induces Melatonin-like Amelioration of Cognitive Deficit in Male Rat
Authors: Barrón-González Mónica , Rosales-Hernández Martha C. , Abad-García Antonio , Ocampo-Néstor Ana L. , Santiago-Quintana José M. , Pérez-Capistran Teresa , Trujillo-Ferrara José G. , Padilla-Martínez Itzia I. , Farfán-García Eunice D. , Soriano-Ursúa Marvin A.
Published: March 2022

Preclinical and clinical evidence supports melatonin and its analogues as potential treatment for diseases involving cognitive deficit such as Alzheimer’s disease. In this work, we evaluated by in silico studies a set of boron-containing melatonin analogues on MT1 and MT2 receptors. Then, we synthesized a compound (borolatonin) identified as potent agonist. After chemical characterization, its evaluation in a rat model with cognitive deficit showed that it induced ameliorative effects such as those induced by equimolar administration of melatonin in behavioral tests and in neuronal immunohistochemistry assays. Our results suggest the observed effects are by means of action on the melatonin system. Further studies are required to clarify the mechanism(s) of action, as the beneficial effects on disturbed memory by gonadectomy in male rats are attractive.