bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance, Structure and Functions of Riddle Game in Həba Community
Authors: Sharndama Cletus Emmanuel , Bumna Justman Kwadas
Published: September 2024

The Həba (Kilba) people live in northern Adamawa State of Nigeria. Həba is the people, while nya Həba is the language.  The people have many rich verbal arts which include folktales, songs, proverbs and riddles. This study aims to examine the performance, structure and functions of riddle game as one of the genres of oral literature. The data for the study was obtained through recording of riddles performed in natural settings. Also, the people older than the researchers were interviewed in order to gather information the functions of riddle game in Hǝba community. Descriptive survey was employed for the study in order to interpret, describe, explain and discuss the data in its natural state.  Qualitative method was therefore adopted for the analysis of the riddles in the corpus of the study. The result showed that the Həba folk riddles have some peculiar organizational and syntactic structures. The organizational structures include invitation to play riddle game, challenging, unraveling, penalising, and turn-taking. The analysis of the syntactic structure of the riddles revealed that the riddle acts are highly standard expressions that permit little or no variations. The art of riddling constitute part of the ancient educational and recreational systems of the Həba people. As a community art, riddle telling enhances cognitive development, promotes social cohesion and unity among the children. This paper therefore aims to examine peculiarity of the performance, the structure, and the functions of riddle as verbal art in Hәba community.
Metode Pembelajaran dan Penanaman Nilai Moderasi pada Materi Pendidikan Agama Islam di Sekolah
Authors: Anam Saeful , Zaman Vela Shofa Royatuz , Iskandar Khusnan
Published: September 2024

The purpose of this journal is to examine how PAI learning strategies instill the ideals of moderation. considering the many disputes arising from social and religious problems in Indonesia. Teaching moderation is one way to address this problem. Because incorporating Pancasila values into society depends heavily on moderation. In this journal, we discuss PAI learning methods, their effects on moderation values, and the factors that drive and hinder PAI learning strategies. The journal's research methodology combines qualitative techniques with descriptive research design. Key informant interviews, documentation, and observations were used to collect data. The findings of this study are expected to provide in-depth analysis and useful suggestions to improve education, especially with regard to teaching students about the need for moderation.
Pendidikan Agama Islam dan literasi Media Sosial dalam Menghadapi Era Informasi Bagi Generasi Muda Indonesia
Authors: Hilal Fikri Lora
Published: September 2024

This study examines the strategic role of Islamic religious education in enhancing social media literacy among young generations in the digital age. Using a qualitative approach through library research, the study explores how Islamic education can contribute to developing critical thinking skills, ethical behavior, and responsible use of social media platforms. The research findings highlight three main roles of Islamic education: shaping character and attitudes aligned with Islamic values in social media usage, integrating learning materials on social media ethics, and fostering awareness of the impact of social media on personal development and society. Furthermore, the study identifies key strategies for implementing social media literacy in Islamic education, including curriculum integration, utilizing social media as a learning tool, and developing critical thinking skills. The research concludes that Islamic education has significant potential in preparing young generations to face the challenges of the digital era by instilling Islamic principles such as tabayyun (verification), tadabbur (contemplation), and tabarruk (seeking blessings) in their online interactions. This holistic approach is expected to contribute to forming a generation of Muslims who are literate, critical, and responsible in their use of social media.
Pusat Pendidikan Islam di Masyarakat Berbasis Masjid
Authors: Dariyanto Dariyanto
Published: September 2024

The study in this study aims to describe the programs and implementation in the mosque as a community education center. This research uses a qualitative approach using a case study that occurred at the H.M. Wijadi Dandangan Mosque, Kediri City. Mosques as the center of  Islamic education for the community have many functions that can be studied more contextually. The findings of this study are that the programs at the H.M. Wijadi Dandangan Mosque, Kediri City as a center for Islamic education in the community have 3 programs. 1. Spiritual education program: tahsin for mothers, sunday morning haromain study, shubuh lecture, thematic routine study, khataman, tabligh akbar. 2. Skill education program: english massive, screen printing and graphic design courses, adhan and iqomah courses. 3. Social education program: friday blessings. The implementation is as follows: The Tahsin Women's Program runs for about 5 years. Reciting every Monday-Thursday starts at pkl. 12.30-p.m. 14.30. Teaching using the sorogan method. By participating in tahsin, they increase friendship, practice reciting in each other's homes and have Qur'anic morals. The English Massive program  has been running for about 5 years. Every Thursday and Saturday. Teaching with the Teacher Center and Pairing methods. The Friday blessing program is routine every Friday. The problems of the mosque as a center of Islamic education in the community among them are the lack of interest of new students for the list  of tahsin of mothers, the number of mothers who are unable to attend the prayer, the lack of socialization of the existence of the mosque which is still new, the age factor affects the ability of students to learn, the lack of consistency and motivation in learning.
Yeşil Yönetim Kavramının Web of Science Veri Tabanına Dayalı Bibliyometrik Analizi
Authors: Çetin Seval , Pehlivanlı Edib Ali , Akın Adnan
Published: September 2024

Yeşil yönetim, çevresel etkileri en aza indirmek ve sürdürülebilirliği sağlamak için hayati öneme sahiptir. Kaynak kullanımı, atık yönetimi ve kirliliği azaltma stratejilerini içeren yeşil yönetim kavramı, kurumsal itibarı ve verimliliği artırır. Yeşil yönetim sayesinde çevreye duyarlı müşteri ve çalışanlar kuruma çekilebilir. Son yıllarda uygulamaya giren sınırda karbon düzenleme mekanizması ve net sıfır hedefi gibi düzenlemelerin de uygulamaya girmesine karşın kavram araştırmacılar tarafından yeterli düzeyde ele alınmamıştır. Bu çalışma ile Web of Science veri tabanında 2000-2023 yılları arasında yayınlanmış olan “yeşil yönetim” başlıklı yayınların bibliyometrik analizi yapılmıştır. Elde edilen 167 yayının türü, yayın yılı, atıf analizleri, yayınların yapıldığı dergiler, yazarların kurumları ve anahtar kelime analizleri VOSviewer yazılımı ile, anahtar kelimelerin trend analizi R temelli Bibliometrix paket ile analiz edilmiştir. Yayınların ağırlıklı olarak sürdürülebilirlik, işletme ve çevre bilimleri konularında, olduğu, makale ve bildiri türünde yayınlandığı gözlemlenmiştir. Yapılan trend analizinde tedarik zinciri yönetimi (supply chain management), performans (performance), sürdürülebilirlik (sustainability), inovasyon (innovation) ve entegrasyon (integration) kavramlarının yeşil yönetimle ilişkili trend kavramlar olduğu görülmektedir.
Hubungan Kualitas Pelayanan Kesehatan Dengan Tingkat Kepuasan Pasien Poliklinik Rawat Jalan HIV/AIDS Rumah Sakit Umum Daerah Djasamen Saragih Tahun 2023
Authors: Dearmalina Sariyunita Saragih  , Sri Rezeki
Published: September 2024

Based on WHO data shows that 5.7 to 8.4 million people die due to poor quality health services each year in low and middle income countries, which represent up to 15% of total deaths in this country. Patients in conditions requiring health care die 60% due to poor service quality and 40% of deaths due to lack of utilization of the health service system, especially in low and middle income countries (WHO, 2020). This study aims to identify the relationship between the quality of health services and the level of patient satisfaction at the HIV/AIDS Outpatient Polyclinic at the Djasamen Saragih Regional General Hospital in 2023. Type of quantitative research with cross sectional design. This research was conducted on a sample of 41 midwives. To measure the characteristics of respondents used a data collection form, to measure the quality of service with the level of satisfaction of respondents used a questionnaire. Based on the relationship between the quality of health services and the level of patient satisfaction, a p-value of 0.000 (p <0.05) was obtained which indicated that there was a significant relationship between the characteristics of midwives, such as the relationship between the quality of health services and the level of patient satisfaction at the HIV/AIDS Outpatient Polyclinic at Home Djasamen Saragih Regional General Hospital in 2023. Thus Ho is rejected, correlation strength (r) = 0.008. The relationship between the quality of health services and the level of patient satisfaction is in the dissatisfied category. It is recommended that many provide policies through the best programs in terms of quality of health services, especially in terms of satisfaction levels at the HIV/AIDS Outpatient Polyclinic, Djasamen Saragih Regional General Hospital
Penyuluhan Pentingnya Vaksin HPV untuk Mencegah Kanker Serviks Sedini mungkin di Kabupaten Takalar
Authors: Sumarmi Sumarmi  , Salmah Arafah  , Ernawati Ernawati  , Kamriana Kamriana  , Mantasia Mantasia  , Riska Nuryana  , Alwi Alwi  , Sri Kurnia Sah Puteri  , Dewi Dewi
Published: September 2024

Cervical cancer is one of the most common types of cancer in the female genital organs caused by human papillomavirus (HPV), and preventive measures are highly recommended rather than curative measures. Prevention efforts are still poorly understood, so education is needed to increase vaccination coverage. The aim of this service is to increase participants' understanding of cancer vaccines. This method was used to discuss with partners at SDN Pusat No. 1 Patalasang District. Takalar, and students and teachers participate. Participants' knowledge was assessed through pre-test and post-test. The test result in front of 6 teachers and 15 students was 71.4, increasing to 98.2 at the time of the test. All service participants were satisfied with the implementation of the service because they felt the information was very useful and they needed it. All participants feel the benefits of using the services. Participants hope to continue this service in the future with free pap smears and vaccinations. It can be concluded that advice on cancer prevention and vaccination increased participants' understanding from 71.4 to 98.2 and was highly appreciated by the participants.
Tingkat Pengetahuan Orang Tua tentang Penanganan Hipertermia pada Anak di Puskesmas Pahandut
Authors: Vina Agustina  , Karmilawati Karmilawati
Published: September 2024

Background: Hyperthermia is an abnormally high body temperature caused by thermoregulatory dysfunction. High fever can lead to shock, which, if not treated promptly, can result in death. Hyperthermia in children is commonly caused by viral infections, excessive heat exposure, dehydration, allergies, and immune system disorders. Objective: To determine the level of parental knowledge regarding the management of hyperthermia in children at Pahandut Health Center. Method: This study used a questionnaire design with a sample of 31 respondents at Pahandut Health Center. Results: The research results showed the level of parental knowledge about hyperthermia management at Pahandut Health Center, with 31 respondents categorized as follows: 14 respondents (45%) had good knowledge, 14 respondents (45%) had sufficient knowledge, and 3 respondents (10%) had poor knowledge. Conclusion: The study highlights the importance of parental knowledge in preventing hyperthermia in children.
Asuhan Keperawatan Pada Nn. S dengan Post Operasi Hernioraphy : Hernia Inguinalis Lateralis Dextra di Ruang Mawar 2 RSUD dr. Soeselo Kabupaten Tegal
Authors: Silvia Desti Arlina  , Ahmad Zakiudin  , Sukirno Sukirno
Published: September 2024

Inguinal hernia is a condition where an organ protrudes into a cavity through a thin or weak part of the wall. The small intestine is usually the organ that enters the cavity, causing the protrusion. In 2018, hernia ranked 8th in Indonesia with a total of 18,145 cases or around 1.05%. The number of hernia cases in Central Java is estimated to be over 500, or approximately 1.01% of cases. If an inguinal hernia is not treated promptly, it will continue to grow and exert significant pressure on the surrounding tissues. A common consequence of untreated hernia is that it will enlarge and interfere with the patient's daily activities. One of the complications of hernia is swelling around the lump. One of the treatments for hernia is surgery. The writer is expected to provide optimal nursing care for patient. S, who has experienced a right lateral inguinal hernia post- operatively following herniorraphy in Mawar 2 ward of dr. Soeselo Regional Hospital, Tegal Regency.
Citizen Satisfaction's Determinants with the Integrated Public Services Quality Provided by One-Stop-Shop. A case from a Western Balkan Country
Authors: Kurti Sllavka , Kina Kristian
Published: September 2024

Government One-Stop Shops are promoted as a strategy for improving intergovernmental collaboration, coordinating "Weberian" bureaucratic structure, and streamlining service delivery using technology. One-stop-shop models, which are seen as a significant accomplishment in recent e-government initiatives, aim to provide public service delivery mechanisms that are efficient, accessible, coordinated, and cost-effective. The purpose of this research paper is to assess citizens' satisfaction with the quality of integrated public services provided by One-Stop Shop (OSS), with a particular emphasis on the relationship between citizen satisfaction with the quality of OSS services and determinant dimensions of trust, procedures, staff skills and qualifications, time and cost savings, and perceived citizen care/support. This paper employs a quantitative approach method through a survey as a research instrument. A structured questionnaire is distributed to 114 citizens receiving service in OSS in a municipality in south Albania, a western Balkan country. The study's primary objective is to provide top-level managers of the OSS agencies and policymakers with an effective instrument for better evaluating and understanding the perceived quality of their integrated public services offered from the perspective of their citizens. This understanding aims to facilitate the formulation of more effective policies and strategies that foster the ongoing enhancement and incorporation of novel public management best practices. The findings of the multi-regression analysis reveal that the factors - Saving, Staff, Support, Procedures, and Trust had a positive and statistically significant impact on satisfaction, accounting for 85.8 per cent of the variation values of citizen satisfaction with the quality service provided by One-Stop Shop.
Availability of Services for Families of Children with Disabilities in Lithuania by View of Heads of Social, Health and Education Institutions in the Alytus Region
Authors: Gardziulevičienė Laura , Raišienė Agota Giedrė
Published: September 2024

Family support is a crucial component affecting the functioning of parents of children with disabilities within society. Sufficient services that cater to both child support and the parents' quality of life are required, or else the state labor market runs the risk of losing able-bodied citizens who are responsible for raising children with disabilities. Thus, the research has twofold aim: to review the system of public services for families raising children with disabilities in Lithuania, and to analyze the availability of services from the perspective of managers of service-providing institutions. A structured interviews was conducted to collect information from eighteen experts who are heads of education, health and social services departments of municipalities and subordinate institutions, responsible for decision-making in the organization and provision of services to families raising children with disabilities in the Alytus region. According to research findings, the Alytus region has the potential to provide education, healthcare, and social services following legal provisions. However, the current range of services is inadequate in practice. Typically, most services are available only upon parental request for children with disabilities, with certain services not being available for numerous reasons. Based on the research findings, the insufficient provision of services in the Alytus region is mainly attributable to a shortage of service staff and limited financial resources. At the same time, the study highlights a slow responsiveness of the municipalities and their subordinate entities towards communicating and collaborating, as well as with parents of disabled children.
Improving risk management tools through updating a risk register
Authors: Gavrilov E. , Bezrukova Tatyana , Ilunina Anna
Published: September 2024

The article contains substantiated recommendations of recommendations for improving standards project management standards (PMI PMBoK 6 and IPMA ICB 4.0) regarding project risk management, which were formed based on an analysis of their weaknesses. It is proposed to improve risk management tools by updating the risk register, which allows eliminating identified weaknesses.
The impact of plastic on the ecosystem of the seas and oceans
Authors: Pshenichnov D. , Maklakova Elena
Published: September 2024

Plastic pollution poses a serious threat to marine and oceanic ecosystems around the world. The constant accumulation of plastic debris by humans in water systems leads to direct or indirect damage to the structure, functioning and value of these systems. The sources of these toxic substances are both terrestrial and marine sources, which carry pollution into the ocean in various forms. The purpose of this article is to highlight various aspects of the problem of plastic pollution of marine and oceanic spaces. Plastic pollution is present in the ecosystem in various shapes and sizes, including micro-plastics, macro-plastics and mega-plastic particles. Micro-particles of plastic in primary and secondary forms spread through surface water masses, bottom sediments and living organisms inhabiting the marine and coastal environment.
Factors of difference between cultures and their influence on human behavior
Authors: Ermakov S. , Nedoseikina S. , Gurovskaya E.
Published: September 2024

This article explores the importance of cultural dimensions and their impact on human behavior in various types of society. The differences in culture, values and norms that shape the behavior of people in different countries and socio-cultural environments are analyzed. The results of the work will help to better understand the diversity of cultures and adapt strategies for interacting with people from different cultural environments, which contributes to the creation of more successful and adapted products and services.
Model for the formation of the content component of training exercises for the practical mastery of electronic warfare equipment by specialists
Authors: Khasanov V. , Potapov A.
Published: September 2024

The paper considers the issue of developing a model for forming the content component of training exercises for the practical development of electronic warfare equipment by specialists. It is shown that the model for forming the content component of training exercises differs in that when using radio monitoring of the functioning of electronic warfare equipment and using the methodology for forming the content component of training exercises, it allows the selection of prescribed conflict-resistant operations in accordance with the radio frequency conditions of the functioning of electronic warfare equipment.
PERLINDUNGAN HUKUM BAGI MASYARAKAT DALAM TRANSAKSI JUAL BELI GAS LPG 3 KILOGRAM MENURUT UNDANG-UNDANG NOMOR 8 TAHUN 1999 TENTANG PERLINDUNGAN KONSUMEN
Authors: Faizal Idris Reza , Sulistiyantoro Heru
Published: September 2024

To meet the needs of life, there is a relationship between business actors and consumers. The relationship between business actors and consumers is interdependence. To protect the interests of consumers, the Consumer Protection Act is urgently needed due to the weak position of consumers towards business actors. The purpose of this study was to determine the form of legal protection for consumers in obtaining 3 kilograms of LPG (Liquified Petroleum Gas) at a price according to the HET (Highest Retail Price). The research method used in this study was a normative juridical research method with data collection through library research and interviews in order to collect and study library materials or secondary data. The result of the research is that regulations regarding consumer legal protection and consumer disputes in Indonesia have been regulated in Law Number 8 of 1999 concerning Consumer Protection. In addition, socialization is needed from the government and related institutions regarding the rights of 3 kg lpg consumers, such as the right to obtain information about the price of 3 kg lpg, information about the availability of 3 kg lpg gas at bases and so on, especially in the city of Surabaya.
Upaya Peningkatan Hasil Belajar Siswa Kelas V Pada Mata Pelajaran Bahasa Indonesia Melalui Metode Pembelajaran Role Playing di SDN Pandan
Authors: Mamluatur Rohmah  , Agung Setyawan
Published: September 2024

The purpose of this study was to find out the learning outcomes of students at the elementary level through the Role Playing method. The learning outcomes of each student are different so there is a need for this research to examine this. Based on the results of student evaluations in learning material for fiction stories, fifth grade students at SDN Pandan showed very low learning evaluation results. This can be seen from several students, who obtained a 60% level of learning outcomes. This happens because of the lack of students in understanding the Role Playing material. This study uses a type of classroom action research using data collection techniques in the form of observation and tests. The research instrument used observation sheets in the form of teacher activity observation sheets and student observation sheets. The data analysis technique used is descriptive qualitative.
Peran Badan Usaha Milik Desa(BUMDes) Dalam Meningkatkan Perekonomian Masyarakat di Desa Batu Belanak Kecamatan Suak Midai Kabupate Natuna
Authors: Nur Izzati  , Afrizal Afrizal  , Eki Darmawan
Published: September 2024

Village-Owned Enterprises are institutions that operate in the field of managing village economic resources which aim to optimize village assets, improve community businesses and increase village income. This increasingly narrow agricultural area has caused the people of Batu Belanak Village to complain because some of their harvests have failed, such as coconuts, the quality of the coconut harvest is not good so it is not suitable for sale and consumption by the local community. This research method uses qualitative research. The data collection technique is using interviews and documentation. There are 4 indicators according to Siagian's role theory (2000:142-150), namely Stabilizer, Innovator, Pioneer and Modernizer. The results of this research show that the role as a stabilizer for the sale of electricity tokens and telephone credit, cattle fattening is one of the BUMDes programs that is running in Batu Belanak Village, the need for cattle, especially Midai Island, the price of sacrificial cattle is too high and the cows that come out will get big profits, fishing gear for Village BUMDes fishermen Batu Belanak provides credit for goods. BUMDes provides credit for goods in installments. The role of BUMDes innovator in Batu Belanak Village will be to create a household credit program. The government's role as a pioneer is to first implement innovation to build cooperation with the community in terms of advancing the village. Role as a modernizer from traditional to modern conditions.
Validity argument of an Interactional Competence checklist: Perspectives and many-facets Rasch analysis
Authors:   Shiraz University, Montasseri Zahra , Ahmadi Alireza ,   Shiraz University
Published: September 2024

The continued scrutiny of interactional competence (IC) as a sociolinguistically-based construct is gaining momentum in L2 assessment. Previous contributions have emphasized the multi-faceted nature of IC in operationalization and assessment. Among the few assessment tools developed for IC, May et al.’s (2020) checklist is one of the most comprehensive. This study evaluated the decision inference of this IC checklist based on Knoch and Chapelle’s (2017) argument-based approach to validation. Several sources of data, including test score data, semi-structured interviews, and expert reviews were used to investigate the proposed assumptions. Four raters evaluated 62 upper-intermediate and advanced test-takers’ paired and group oral performances using the adapted IC checklist. Furthermore, five experts in the field of language assessment and 10 language teachers participated in the study. To analyze the data, MFRM analysis through FACETS and thematic analysis were employed. The results provided partial evidence for the assumptions, thus leading to an overall partial support to the decision inference. The IC checklist showed to be a valid instrument for differentiating between test-takers at different IC levels, interpreting scores, and informing teaching and learning. The major drawback of the checklist was associated with a lack of descriptive levels and numerical values.
Examining the Relationship between Students’ Perceptions of Instructor Communication of Power Online and Student Online Course Endorsement
Authors: Cole Andrew William , Kim Sang-Yeon , Priddis DeAnne ,   Pennsylvania Communication Association
Published: September 2024

The study examined the relationship between student perceptions of instructor power communication online and student endorse-ment of online courses. A series of logit models sought to answer whether perceived power relationships and instructor use of bases of powers predicted students’ self-reported willingness to (1) take another online course, and (2) recommend online courses to friends. Three instructor-student power relationships emerged from the current data. Students identifying a “leader-follower” relationship appeared significantly more likely to report intent to take further online courses and recommend online courses than students identifying “expert service provider-consumer” or “punisher-punished” relationships. Perceived instructor use of specific bases of power failed to predict online course endorsement.
Pharmacopoeias
Authors: Tiwari Mr. Prabhakar Singh
Published: September 2024

Pharmacopoeias are official publications containing a list of medicinal drugs with their effects and directions for their use. They serve as authoritative reference texts for drug quality and standards. The Indian Pharmacopoeia (IP) is the official compendium of drug standards in India, published by the Indian Pharmacopoeia Commission (IPC). It ensures the quality, safety, and efficacy of medicines produced and consumed in India. The British Pharmacopoeia (BP) is the authoritative collection of standards for UK medicinal products and pharmaceutical substances, published annually under the supervision of the Medicines and Healthcare products Regulatory Agency (MHRA). The United States Pharmacopoeia (USP) is a scientific, non-profit organization that sets standards for the quality, purity, strength, and consistency of medicines, food ingredients, and dietary supplements consumed worldwide. The Extra Pharmacopoeia, commonly known as Martindale: The Complete Drug Reference, provides comprehensive information on drugs and medicines used globally. It includes details on drug interactions, side effects, and clinical uses, making it an essential reference for healthcare professionals. Each of these pharmacopoeias plays a crucial role in maintaining drug quality and ensuring public health by providing standardized guidelines for the preparation and use of pharmaceuticals.
Powders-I
Authors: Jain Mr. Ashutosh
Published: September 2024

Powders are finely divided solid dosage forms containing one or more active pharmaceutical ingredients (APIs) and excipients. They can be used internally or externally and are often the basis for other dosage forms such as tablets and capsules. The definition of powder highlights its physical state and versatility in pharmaceutical formulations. Powders can be classified based on their particle size, intended use, and method of preparation. For example, they are categorized as bulk powders, which are supplied in large quantities, and divided powders, which are individually packaged in unit doses. Other classifications include effervescent powders, which release gas when in contact with water, and dusting powders, which are applied to the skin for therapeutic or protective effects. The advantages of powders include their stability and long shelf life compared to liquid formulations. They offer flexibility in dosing, as they can be easily measured and adjusted. Powders are also suitable for patients who have difficulty swallowing tablets or capsules and can be administered in various ways, including orally, topically, and through inhalation. However, powders have certain disadvantages. They can be inconvenient to handle and store due to their bulkiness and the potential for spillage and dust formation. The uniformity of dose can be challenging to achieve, especially in bulk powders. Powders can also be hygroscopic, absorbing moisture from the air, which may affect their stability and efficacy.
Liquid Dosage Forms
Authors: Ruksaar Mrs. Saba
Published: September 2024

Liquid dosage forms are pharmaceutical preparations in which the active ingredients are dissolved, suspended, or emulsified in a suitable liquid vehicle. These forms include solutions, suspensions, emulsions, syrups, and elixirs, providing versatile means for administering medications. The advantages of liquid dosage forms are numerous. They offer flexibility in dosing, which is particularly beneficial for pediatric and geriatric patients who may have difficulty swallowing solid forms. Liquids can also provide faster onset of action as the drug is already in dissolved form, facilitating quicker absorption. Additionally, they allow for the incorporation of multiple active ingredients and are suitable for patients requiring enteral feeding. However, liquid dosage forms also have disadvantages. They are generally less stable than solid forms, with a higher risk of microbial contamination and degradation over time. They often require preservatives to maintain stability and can be bulky and inconvenient to transport and store. Precise dosing can be more challenging compared to pre measured solid forms, necessitating careful measurement. Excipients play a crucial role in the formulation of liquid dosage forms. Common excipients include solvents (e.g., water, ethanol), preservatives (e.g., parabens, benzalkonium chloride), sweeteners (e.g., sucrose, sorbitol), flavoring agents, and stabilizers. These excipients ensure the product's stability, palatability, and safety. Solubility enhancement techniques are vital for drugs with poor aqueous solubility. Methods such as pH adjustment, the use of cosolvents (e.g., propylene glycol, ethanol), surfactants (e.g., polysorbates), complexation (e.g., with cyclodextrins), and particle size reduction (e.g., micronization) are commonly employed. These techniques improve the bioavailability of the drug by increasing its solubility and dissolution rate
Antinociceptive Potential of Dichloromethane Extract of Rumex acetosa Leaf in Albino Rats
Authors: Stephen Hyelda , Nakya Faith Emmanuel , Sirante Richard Martin
Published: September 2024

Rumex acetosa (Polygonaceae) is an ethnomedicinal herb and vegetable used to alleviate pain and inflammation. It is also commonly consumed as food. This study aimed to evaluate the antinociceptive effects of dichloromethane extracts from R. acetosa leaves using in vivo pharmacological models in albino rats. Dried leaf powder was extracted by maceration with dichloromethane (72 h). Acute oral toxicity was determined per OECD guidelines. Analgesic activity was assessed using tail immersion, hot plate (55°C) and acetic acid-induced writhing (0.7%) tests at doses of 50, 100 and 200 mg/kg body weight. Diclofenac sodium (25 mg/kg) served as reference drug. Phytochemical analysis was undertaken to screen major chemical classes. All doses of extract significantly (p<0.05) increased mean basal latency of tail withdrawal and hind paw licking by 46-162% and 63-207% respectively. Maximum analgesic effect comparable to diclofenac was observed at 200 mg/kg. In acetic acid model, extract exhibited marked (p<0.05) reduction in writhing frequency (55.49%) indicative of peripheral action. Preliminary phytochemical studies detected flavonoids, alkaloids, tannins and phenols as major compounds. R. acetosa leaf extracts displayed significant analgesic activity in vivo mediated via both central and peripheral pathways. The findings validate the traditional use of R. acetosa in pain management.
Analytical and Clinical Validation of the Oncomine Dx Target Test to Assess HER2 Mutation Status in Tumor Tissue Samples From Patients With Non–Small Cell Lung Cancer Treated With Trastuzumab Deruxtecan in the DESTINY-Lung01 and DESTINY-Lung02 Studies
Authors: Qi Zhenhao , Ha Thomas , Feng Wenqin , Karnoub Maha , Pereira Kaline , Shiga Ryota , Smit Egbert F. , Goto Yasushi , De Langen Adrianus Johannes , Goto Koichi , Velasco Roth Anne Marie , Khambata-Ford Shirin
Published: September 2024

Context.—

Trastuzumab deruxtecan (T-DXd), a human epidermal growth factor receptor 2 (HER2)–targeted therapy, has demonstrated durable anticancer activity in patients with advanced, metastatic HER2 (also known as ERBB2)–mutant (HER2m) non–small cell lung cancer (NSCLC) who have limited treatment options and poor prognosis.

Objective.—

To analytically validate and assess the clinical utility of the Oncomine Dx Target (ODxT) Test as a companion diagnostic to identify patients with HER2m NSCLC.

Design.—

Tumor samples from patients in DESTINY-Lung01 and DESTINY-Lung02 were retrospectively analyzed alongside commercially procured samples using the ODxT test and compared to the assays used for screening in these clinical trials.

Results.—

Positive percent agreement (PPA) and negative percent agreement (NPA) between the ODxT Test and TruSight Tumor 170 assay when testing DESTINY-Lung01 and commercially procured samples met prespecified thresholds (PPA and NPA ≥90%) for analytical accuracy (100% and 99.1%). The ODxT Test results were highly concordant with clinical trial assays (CTAs) used in DESTINY-Lung01 (PPA and NPA, 98.0% and 100%) and DESTINY-Lung02 (PPA and NPA, 96.7% and 100%) to identify activating HER2 mutations in tumor samples. Confirmed objective response rates were similar between patients with HER2m tumors identified by the ODxT Test and by CTAs in DESTINY-Lung01 (58.3% and 54.9%) and DESTINY-Lung02 (53.6% and 53.8%). Response duration was 12.0 and 9.3 months for patients identified by the ODxT Test and CTAs, respectively, in DESTINY-Lung01.

Conclusions.—

The ODxT Test detected HER2 mutations in NSCLC with high analytical and clinical accuracy and identified HER2m populations with response rates similar to populations identified by CTAs, supporting clinical utility of the ODxT Test to inform treatment decisions for HER2m NSCLC.
E-Reading Adoption and Digital Literacy in Rural Bangladesh: Overcoming Barriers and Improving Educational Outcomes
Authors: Munira Sirajum , bin Ahsan Wahid
Published: September 2024

This study examines the adoption and impact of e-books and PDFs among students in rural Bangladesh, exploring how digital reading influences study habits and educational outcomes. In-depth interviews with 27 participants, including students, teachers, and parents, reveal patterns of e-reading adoption, its effects on learning, and the challenges of accessing digital resources in rural areas. The research also investigates the role of educational and parental support and the broader cultural and social implications of digital learning in these communities. Key findings show that while students recognize the benefits of e-books, they face significant barriers, including limited access to devices, unreliable internet connectivity, and a lack of digital literacy training. The study emphasizes the need for targeted interventions to improve digital infrastructure and support systems in rural schools, offering practical insights for policymakers and educators.
Existence and bounds for Kneser-type solutions to noncanonical third-order neutral differential equations
Authors: Purushothaman Ganesh , Suresh Kannan , Thandapani Ethiraju , Tunc Ercan
Published: September 2024

This article focuses on the existence and asymptotic behavior of Kneser-type solutions to third-order noncanonical  differential equations with a delay or advanced argument in the neutral term $$ \Big(r_2(t)\big(r_1(t)z'(t)\big)'\Big)'+g(t)x(t)=0, $$ where \( z(t)=x(t)+p(t)x(\tau(t))\). This equation is transformed into a canonical equation, which reduces the number of classes of positive solutions from 4 to 2. This is done without assuming extra conditions, and greatly simplifies the process of obtaining conditions for the existence of Kneser-type solutions. Also we obtain lower and upper bounds for these solutions, and obtain their rate of convergence to zero. Two examples are provided to illustrate our main results, one with a delay neutral term, and one with an advanced neutral term. 
For more information see https://ejde.math.txstate.edu/Volumes/2024/55/abstr.html
Pengaruh Lingkungan Kerja, Motivasi Kerja Dan Disiplin Kerja Terhadap Kinerja Guru Di Kidsstar School Makassar
Authors: Ariyanto Andi
Published: September 2024

Penelitian ini dilakukan di Kidsstar School Makassar untuk mengetahui; 1) apakah lingkungan kerja berpengaruh terhadap kinerja guru di Kidsstar School Makassar. 2) apakah motivasi kerja berpengaruh terhadap kinerja guru di Kidsstar School Makassar. 3) apakah disiplin kerja berpengaruh terhadap kinerja guru di Kidsstar School Makassar. 4) apakah lingkungan kerja, motivasi kerja dan disiplin kerja secara simultan berpengaruh terhadap kinerja guru di Kidsstar School Makassar. Data dikumpulkan dari survei lapang menggunakan kuesioner yang dibagi ke seluruh guru dengan jumlah 35 orang. Metode penelitian ini adalah kuantitatif dengan metode sampling jenuh digunakan untuk menentukan sampel. Data yang akan dianalisis harus memenuhi uji validitas dan reabilitas serta uji asumsi klasik seperti normalitas, heteroskedasitas, dan multikolinieritas. Metode yang digunakan adalah regresi linear berganda, dengan bantuan software SPSS. Metode pengambilan sampel adalah metode sampling jenuh atau sensus, dimana keseluruhan dari jumlah 35 guru dijadikan sampel pada penelitian ini. Hasil Penelitian menunjukkan bahwa variabel lingkungan kerja, motivasi kerja dan disiplin kerja secara parsial maupun simultan berpengaruh positif dan signifikan terhadap kinerja guru di Kidsstar School Makassar.
Impact of The Corporate Governance on Sustainability Report Disclosure with Environmental Performance as A Moderation Variable in Indonesia
Authors: Rumaningsih Dewi Windary , Rusmanto Toto
Published: September 2024

This study aims to analyze the effect of corporate governance on sustainability report disclosure, with environmental performance acting as a moderating variable. The analysis focuses on the role of the board of directors, independent commissioners, audit committees, and financial performance in influencing the quality of sustainability reporting, particularly within the Indonesian context. Environmental performance is measured using the PROPER scale. The study utilizes data from the annual and sustainability reports of 20 companies in the basic materials and energy mining sectors listed on the Indonesia Stock Exchange from 2018 to 2022, amounting to 100 observations. The data is processed using SPSS 23. The results show that the presence of female directors significantly enhances the quality of sustainability disclosures, as they tend to prioritize social responsibility. Moreover, financial performance, as measured by Return on Assets (ROA), positively affects sustainability reporting, with companies in better financial health being more transparent in their disclosures. Environmental performance, when combined with strong independent oversight, further improves reporting quality, reflecting the positive influence of independent commissioners and sound financial governance. The study concludes that environmental performance, as measured by the PROPER scale, plays a significant role in improving sustainability disclosures in Indonesia. It recommends that the Indonesian government provide stronger support and clearer regulations to help companies improve their sustainability practices and contribute to the G20 agenda.
Adopting a Tourist Perspective and Organizational Behavior to Strategically Improve Tourism Sustainability
Authors: Saragih Darwin Raja Unggul , Idris Panca Purakusuma , Anggiani Sarfilianty
Published: September 2024

Tourism is a rapidly expanding global economic sector, contributing significantly to economic growth and social development. However, its expansion also poses challenges such as environmental degradation, socio-cultural disruptions, and economic inequalities. Sustainable tourism, which aims to balance economic, social, and environmental factors, is crucial for ensuring the long-term viability of the industry. This study explores the role of tourist perspectives, organizational behavior, and strategic management in promoting sustainable tourism, using Lake Toba, Indonesia, as a case study. A quantitative approach employing Structural Equation Modeling-Partial Least Squares (SEM-PLS) is used to analyze the relationships between these variables. Findings reveal that tourist perspectives, organizational behavior, and strategic management all significantly impact tourism sustainability. The research provides insights and practical recommendations for tourism destination managers and policymakers to develop strategies that align with sustainability principles, ultimately contributing to the long-term well-being of local communities and the environment.
Analisis Gap Komunikasi pada Film Born To Fly 2023
Authors: Putri Maharani Agnes , Herika Hermanu Diajeng
Published: September 2024

Penelitian ini bertujuan untuk menganalisis film Born To Fly, yang menceritakan mengenai gap komunikasi yang terjadi antar generasi pada kapten Zhang dan Lei Yu, sebagai generasi milenial dan generasi Z. Pada analisis  ini akan dilakukan melalui sudut pandang generasi yang berbeda ,yaitu generasi X, Milenial, dan Z,  dimana data akan di kumpulkan melalui informan dari masing-masing generasi, yaitu Informan generasi X yang  berusia 53 tahun, generasi milenial dengan usia 34 tahun dan juga informan dari generasi Z, yang berusia 21 tahun, dimana informan akan memberikan informasi tentang bagaimana film ini di terima dari sudut pandang generasi yang berbeda.  Penelitian ini memiliki tujuan untuk menganalisis faktor-faktor pendukung dan penghambat yang dapat mempengaruhi gap komunikasi antar generasi dalam film Born To Fly. Pada analisis  ini menggunakan metode kualitatif dengan menggunakan pendekatan semiotika, yang terfokus pada gap komunikasi dan analisis tanda-tanda yang di tunjukan pada setiap scene tertentu di dalam film Born To Fly, dengan menggabungkan perspektif generasi yang berbeda dan menggunakan analisis semiotika. Hasil menunjukkan bahwa terdapat pengaruh gap komunikasi antar generasi, yang di sebabkan akibat adanya perbedaan persepsi, budaya dan pengalaman antara Lei Yu dan Kapten Zhang, sehingga timbul pendapat yang berbeda dalam situasi yang sama, yang menyebabkan karakter Lei Yu, dapat bertumbuh.
PENGARUH KUALITAS LAYANAN AKADEMIK DAN KOMPETENSI DOSEN SERTA CITRA INSTITUSI TERHADAP KEPUASAN MAHASISWA PADA AKADEMI MARITIM NASIONAL JAKARTA RAYA
Authors: Bangun Husodo
Published: September 2024

Tujuan  penelitian  ini  untuk  mengetahui  pengaruh    kualitas  layanana  akademik, kompetensi  dosen  dan  citra  institusi  terhadap  kepuasan  mahasiswa  pada  Akademi  Maritim Nasional Jakarta Raya.  Desain penelitian menggunakan  desain explanative research dengan menggunakan  pendekatan  kuantitatif    yang  menjelaskan  hubungan  antar  variable.  Objek penelitian  adalah      mahasiswa  Akademi  Maritim  Nasional  Jakarta  Raya,  jumlah  sample 135mahasiswa.  Seleksi  sample  secara  purposive  sampling.  Data  primer  dari  pengisian kuesioner  oleh  responden.  Analisis  Statistik    menggunakan  aplikasi  SPSS  versi  25.0  dan Aplikasi  Lisrel  8.80  untuk  mengolah  data    Structural  Equation  Modeling  (SEM).    Hasil penelitian,  menyatakan  bahwa  variabel    Kualitas  pelayanan    berpengaruh    postif  terhadap  Kepuasan  mahasiswa, Sedangkan  variabel Kompetensi Dosen  pengaruhnya tidak  signifikan terhadap Kepuasan  mahasiswa begitu juga variabel Citra Institusi berpengaruh negatif terhadap Kepuasan  mahasiswa.
Pengaruh Gaya Berpikir dan Pengetahuan Awal Terhadap Kemampuan Pemecahan Soal Cerita Matematika
Authors: Hidayat Kurahmadan
Published: September 2024

Tujuan penelitian ini adalah untuk menganalisis dan menguji hipotesis pengaruh gaya berpikir dan pengetahuan  awal  siswa  terhadap  kemampuan    pemecahan  soal  cerita  matematika.  Hipotesis penelitian ini meliputi: 1) Terdapat pengaruh gaya berpikir terhadap kemampuan pemecahan soal cerita matematika. 2) Terdapat pengaruh pengetahuan awal terhadap kemampuan pemecahan soal cerita matematika. 3) Terdapat pengaruh interaktif gaya berpikir dan pengetahuan awal terhadap kemampuan  pemecahan  soal  cerita  matematika.  Metode  yang  digunakan  dalam  penelitian  ini adalah Survey Expose Facto. Populasi terjangkau adalah kelas VII MTs Negeri di Jakarta Timur. Besar  sampel  sebanyak  88  siswa,  dengan  teknik  sampling  yang  digunakan  teknik  random sampling. Instrumen penelitian yang digunakan yaitu tes uraian kemampuan pemecahan soal cerita matematika  pada  bab  bangun  datar  segitiga  dan  segi  empat  sebanyak  9  soal  yang  telah  diuji validitasnya dan koefisien  reliabilitasnya 0,710; instrumen gaya berpikir sebanyak 20 soal yang telah  diuji  validitasnya  dan  koefisien  reliabilitasnya  0,696;  dan  instrumen  pengetahuan  awal sebanyak 22 soal yang telah diuji validitasnya dan koefisien reliabilitasnya 0,826. Analisis data menggunakan  analisis  of  varians  (ANAVA)  dua  jalur.  Hasil  pengujian  hipotesis  penelitian diperoleh simpulan sebagai berikut: 1) Terdapat pengaruh yang signifikan gaya berpikir terhadap kemampuan pemecahan soal cerita matematika dengan sig. 0,07. 2) Terdapat pengaruh yang tidak signifikan pengetahuan awal terhadap kemampuan pemecahan soal cerita matematika  dengan sig. 0,913. 3) Terdapat pengaruh interaktif yang tidak signifikan gaya berpikir dan pengetahuan awal terhadap kemampuan pemecahan soal cerita matematika dengan sig. 0,268.