bluuebunny/crossref_metadata_2025 huggingface dataset:
Modified Learning Management System: Making A Difference In E-Learning This New Normal
Authors:   Santa Rosa City, Laguna Philippines 4026, F. Agustin Louie
Published: May 2022

The Learning Management System (LMS) is a type of web-based software that is hosted on a server and is used to handle students' information, program enrollment, course content, and evaluation tools. The primary goal of this study was to ascertain the efficacy of learning management systems in affecting change in this new normal school context. The research study engaged 38 students from various courses who were enrolled in the Citi Global College's Weekend Education Program. A descriptive research design was adopted in this study. Descriptive research is one in which the range of one or more variables is described without respect for any causal or other assumption. The frequency (f) and percentage (%) relevant factors were used to determine the respondents' demographic profile in terms of age, sex, course, year level, available internet connection, and gadget use at home; whereas the weighted Mean (WM), ttest, and f-test variables were used to analyze the gathered data regarding the level of effectiveness on the quality characteristics of the learning management system and to determine if there were significant differences in respondents' assessments. The study's findings indicate that respondents were all working students; the majority of them use mobile data as their available internet subscription; and that there was no significant difference in the level of effectiveness of LMS's quality characteristics when respondents were grouped according to their demographic profile. The study recommended that instructors allow students sufficient time to process their output at the LMS because they were working students; prepare video tutorials to familiarize students with the LMS platform; use a good or faster internet connection of at least 4 Mbps and at least Android Marshmallow or iOS 8 on their mobile devices; and that the Learning Management System may be proposed for use by other neighboring schools.
Grey literature: The evidence not published in commercial publications
Authors: Rambe Agung Olaf Ridho , Mono Umar , Perangin-angin Alemina Br
Published: May 2022

Grey literature will be discussed in this paper, as well as what it is and how it impacts people. Grey Literature refers to materials and research created by groups that do not follow the most usual or standard publication and distribution channels. Grey Literature refers to materials and research created by groups that do not follow the most usual or standard publication and distribution channels. The objective of this article is to assist the reader comprehend "what if" the paper has always been made by certain people who we have always looked at as common, but suddenly have a new perspective and are not doing it in the traditional way. We can argue it is for the officials' personal use, but it is sometimes made public, and there may be a lack of systematic distribution and collection methods. A comparative analysis of literature and Grey Literature, which will be contrasted in the topic, will be included in the research.
Diversidad de anfibios en un área periglaciar del Campo de Hielo Patagónico Sur, patagonia chilena
Authors: Raimilla Víctor
Published: May 2022

Se estudió la comunidad de anfibios del sector “Predio Nahuel”, del área protegida privada “Parque La Tapera” ubicada en un área cercana al Ventisquero Jorge Montt, límite norte del Campo de Hielo Patagónico Sur. Esta zona periglaciar es geológicamente reciente, y aparece posterior al retroceso glaciar ocurrido entre los años 1945 y 1976, por lo que su superficie aún es dominada por afloramientos rocosos. Se registró un total de 101 individuos de seis especies: Alsodes coppingeri, Batrachyla antartandica, Chaltenobatrachus grandisonae, Nannophryne variegata, Eupsophus calcaratus e Hylorina sylvatica. Ambientes de pozas y riachuelos fueron los hábitats con mayor diversidad. Se describen los microhábitat de la nueva población de C. grandisonae.
Can ‘SOVAC’- a set of brain magnetic resonance imaging findings- detect idiopathic intracranial hypertension?
Authors: Waheed Khawaja bilal , Al Orf Ali , Alzahrani Faisal Mohammad , Aljubair Nawaf Nasser , Sharahili Hussain Hadi , Qamar Adeel , Muthaian Jebasingh
Published: May 2022

Objective
To determine diagnostic ability of brain magnetic resonance imaging (MRI) in detection of idiopathic intracranial hypertension (IIH).
Method
This descriptive observational study was conducted in radiology department from Jan. 2018 to Jan. 2021, evaluating MR imaging data of all adult patients (n=107) with clinical presentations of headaches. Patients with space occupying lesions, obstructive hydrocephalus and cerebral venous sinus thrombosis were excluded. Presence of all three brain MRI findings of (i) an empty sella (with or without sellar enlargement), (ii) tortuosity of optic nerves (with or without perioptic CSF prominence) and (iii) non-dilated (or slit-like) ventricles was considered positive for IIH. Imaging was reviewed by two neuroradiologists and consensus reporting was made. Findings of IIH were confirmed by presence of high lumbar opening cerebrospinal fluid (CSF) pressure or symptomatic response towards specific medical treatment. Outcomes of brain MRIs were presented on a 2x2 contingency table.
Results
Sensitivity, and specificity of routine brain MRI findings in detection of IIH were calculated as 76.4% [95% confidence interval (CI), 64.62-85.91%], and 84.6% (95% CI, 69.47-94.14%) respectively.  
Conclusion:
IIH is a known cause of headache. Detection of all three findings of empty sella, tortuosity of optic nerves and non-dilated ventricles on routine brain MRI can predict IIH with greater sensitivity and specificity.
Chapter 19: Drivers and ecological impacts of deforestation and forest degradation
Authors: Berenguer Erika , Armenteras Dolors , Lees Alexander C , Smith Charlotte C , Fearnside Philip , Nascimento Nathalia , Alencar Ane , Almeida Claudio , Aragão Luiz E O , Barlow Jos , Bilbao Bibiana , Brando Paulo M , Bynoe Paulette , Finer Matt , Flores Bernardo M , Jenkins Clinton N , Silva Junior Celso H L , Souza Carlos , García-Villacorta Roosevelt
Published: May 2022

This chapter discusses the main drivers of deforestation and forest degradation in the Amazon, particularly agricultural expansion, road construction, mining, oil and gas development, forest fires, edge effects, logging, and hunting. It also examines these activities’ impacts and synergies between them.
Chapter 2: Evolution of Amazonian biodiversity
Authors: Guayasamin Juan Manuel , Ribas Camila C , Carnaval Ana Carolina , Carrillo Juan D , Hoorn Carina , Lohmann Lucia G , Riff Douglas , Ulloa Ulloa Carmen , Albert James S
Published: May 2022

This chapter reviews the evolutionary history of the Amazon’s terrestrial and riverine ecosystems, involving geological and climatic events operating over millions of years and across the whole of continental South America. The chapter discusses the important roles of geographic barriers, habitat heterogeneity, climate change, and species interactions in generating and maintaining the most biodiverse ecosystems on Earth. This unique history produced heterogeneous environments and diverse habitats at multiple geographic scales, which altered the connections between populations and allowed for the accumulation of the most diverse biota on Earth.
Chapter 3: Biological diversity and ecological networks in the Amazon
Authors: Zapata-Ríos Galo , Andreazzi Cecilia S , Carnaval Ana Carolina , Rodrigues da Costa Doria Carolina , Duponchelle Fabrice , Flecker Alexander , Guayasamin Juan Manuel , Heilpern Sebastian , Jenkins Clinton N , Maldonado Carla , Meneghelli Diego , Miranda Guido , Moraes R. Mónica , Silman Miles , Pinheiro de Almeida Silveira Maria Aurea , Tabet Gabriella , Trujillo Fernando , Ulloa Ulloa Carmen , Arieira Julia
Published: May 2022

This chapter provides an overview of biodiversity in the Amazon, discusses the reasons why this region is so rich in species and ecosystems, and outlines some outstanding ecological processes that make the Amazon an icon of the natural world. Featured terrestrial and aquatic taxonomic groups illustrate how much we know about diversity in the Amazon, and more importantly, how much we still do not know. A clear understanding of biodiversity levels and their spatial and temporal variations is crucial to understanding future stability under different climate change, land use change, forest fragmentation, and deforestation scenarios and informing conservation and restoration efforts.
Chapter 7: Biogeophysical Cycles: Water Recycling, Climate Regulation
Authors: Costa Marcos H , Borma Laura S , Brando Paulo M , Marengo José A , Saleska Scott R , Gatti Luciana V
Published: May 2022

This chapter assesses biogeophysical interactions between the Amazon rainforest and the climate. A historical perspective is presented, highlighting breakthroughs which improved our understanding of the mechanisms by which the rainforest interacts with the atmosphere.
Chapter 1: Geology and geodiversity of the Amazon: Three billion years of history
Authors: Val Pedro , Figueiredo Jorge , Melo Gustavo , Flantua Suzette , Quesada Carlos Alberto , Reinfelder Ying Fan , Albert James S , Guayasamin Juan Manuel , Hoorn Carina
Published: May 2022

This chapter explores how geodiversity evolved over three billion years of history. It shows that periods of continental breakup followed by mountain building ultimately led to the fundamental physiographic subdivisions of the Amazon, and a wealth of landscapes, soils, ore deposits, oil and gas reserves, and freshwater aquifers. Data on the Amazon’s geodiversity support a central theme of the environmental sciences, that the formation of most natural resources (like rare-earth ores, hydrocarbons, freshwater aquifers, and fertile soils) requires natural processes to operate undisturbed over immense periods of geological time and across broad spatial domains.
Chapter 30: Opportunities and challenges for a healthy standing forest and flowing rivers bioeconomy in the Amazon
Authors: Abramovay Ricardo , Ferreira Joice , de Assis Costa Francisco , Ehrlich Marco , Castro Euler Ana Margarida , Young Carlos Eduardo F , Kaimowitz David , Moutinho Paulo , Nobre Ismael , Rogez Herve , Roxo Eduardo , Schor Tatiana , Villanova Luciana
Published: May 2022

This chapter highlights the paradox between the Amazon’s extraordinary socio-biodiversity and its distance from the scientific, technological, and market frontier of the contemporary bioeconomy. It discusses the current socioeconomic structures available in the region, as well as challenges and pathways for a transition to a socially-fair and sustainable bioeconomy.
Chapter 23: Impacts of deforestation and climate change on biodiversity, ecological processes, and environmental adaptation
Authors: Artaxo Paulo , Fonseca de Almeida-Val Vera Maria , Bilbao Bibiana , Brando Paulo M , Bustamante Mercedes , Coe Michael T , Correa Sandra Bibiana , Cuesta Francisco , Costa Marcos H , Miralles-Wilhem Fernando , Salinas Norma , Silvério Divino Vicente , Val Adalberto Luis
Published: May 2022

This chapter presents observed and predicted impacts of climate change on Amazonian ecosystems, focusing on biodiversity, ecosystem services, carbon cycling, fisheries, and emissions from biomass burning. It also considers climate and land-use change feedbacks and highlights knowledge gaps to better understand these complex interactions.
Chapter 17: Globalization, extractivism and social exclusion: Threats and opportunities to Amazon governance in Brazil
Authors: Larrea Carlos , Murmis María R , Azevedo Tasso , Nunes Felipe , Rajão Raoni , Ribeiro Capobianco João Paulo , Rodriguez Garavito César , Soares-Filho Britaldo , van der Hoff Richard
Published: May 2022

From the 1970s on, the Amazon experienced its deepest transformation, becoming a commodity and energy provider for both domestic and international markets, through extraction of natural resources. Living conditions barely improved, and social conflict and violence became widespread, particularly affecting Indigenous peoples and local communities. Conservation efforts also became globalized and achieved significant results. Brazil’s 84% reduction in deforestation from 2005-2012, based on an integrated strategy with high political priority, provides an important case study that can support future policies across the basin. These gains were reversed in recent years, and unsustainable extractivist policies generally prevailed over conservation and the sustainable use of biodiversity in the whole Amazon basin (Chapter 18).
A STUDY OF THE OUTCOMES OF ADVERTISING IN COVID-19 TIME
Authors: Kumar Deepu , Ghangas Dr. Seema
Published: May 2022

This study investigates the relationship between the threat of COVID-19 and consumer testing of a product with complaints about authenticity in advertisements. We suggest that threatening situations like COVID-19 encourage consumers to reduce their uncertainty and increase their choice of products through authentic advertising messages. Because people respond differently to threatening environments based on their pre-existing experience, which is often reflected in a child’s socioeconomic status, we assessed whether the child’s socio-economic status balances the relationship between the threat and consumer authenticity in advertisements. First, the second data from Google Trends provided strong support for our speculation. In an additional exploratory study, participants evaluated different targeted products in four subjects that may have been forgotten or measured COVID-19 threat. Our results provide compelling evidence that consumers are thoroughly evaluating products with authentic advertising messages under the threat of COVID-19. Consumer motivation to reduce their uncertainty is the basis for the effect of the COVID-19 threat in their analysis of factual messages. This effort to reduce uncertainty is more likely to occur to consumers with the highest social and economic status of the child. These findings suggest that the use of factual complaints during an epidemic can effectively reduce consumer uncertainty and produce positive consumer analysis.
E-Marketing Communication and Loyalty in Real Estate Customers Based on Their Income
Authors: Gutiérrez-Velasco Juan R. , Cabral-Olmos David , Marín-Aguilar José T.
Published: May 2022

The real estate industry is one of the most profitable activities worldwide, for instance, GDP-wise in 2020 it had a share of 5.8% within the Mexican economy, that is above 62 billion dollars (Statista, 2022; The World Bank, 2022). An activity with such relevance should keep up with world trends such as digitalization, e-commerce, and communication especially during the pandemic. COVID-19 accelerated the need of a multichannel integration in order to compete in today’s fierce competition. Digitalization has helped companies and people to find each other allowing them to communicate and exchange value, all of these resulting in long relationships. The problem analyzed within this research is made up of the little knowledge the realtors have regarding digital tools and how they can use them in their daily work activities as well as the effect they may have. Therefore, the purpose of this study is to analyze the influence of e-marketing communication on customer’s loyalty in the real estate business and to find out if there are any variations in terms of people's income. PLS-SEM was used so as to determine the link between each of the constructs in the proposed model, results show that e-marketing communication has a favorable and significant impact on customer loyalty, and that this influence is related to people's income.
Interbestuurlijke verhoudingen in de bed-bad-broodcasus
Authors: Bakker Niek
Published: May 2022

Governing relationships between government and municipalities during the shelter crisis of 2015

This article describes the relationship between central government and municipalities and to what extent this relationship has an impact on local decision-making. The commonly used characterization of this relationship as a principal-agent relationship offers many leads but has some shortcomings. That is why this is compared with the stewardship theory, assuming a more equal and constructive cooperation. Both theories have been incorporated into a broader model on management styles, which creates a more nuanced description of the cooperation in public administration. The article focuses on the case of Rotterdam in 2015, at a time of political turmoil in the Netherlands about the shelter of people without residence permit. The analysis is carried out using a measuring instrument for policy freedom, as policy freedom is a good determinant for which management style is used. The research is conducted from a local perspective, with emphasis on the position of councilors. The national government sometimes profiles itself as a principal to them, but in practice council members resist and turn the relationship around, hereby holding the government accountable for its role and responsibility.
Onafhankelijkheid
Authors: Huls E. (Eva) , Trotman T. (Tamara)
Published: May 2022

Onafhankelijkheid

Onafhankelijkheid: een thema dat zowel nationaal als internationaal de gemoederen bezig weet te houden. Hoogste tijd voor een speciaal nummer over dit onderwerp, waarbij in de verschillende bijdragen is geprobeerd het concept onafhankelijkheid vanuit uiteenlopende invalshoeken (OM, ZM en balie) te belichten.
De onafhankelijkheid van de strafrechter
Authors: de Doelder H. (Hans)
Published: May 2022

De onafhankelijkheid van de strafrechter

In 2014 schreef prof. mr. Doelder in zijn afscheidsrede over de onafhankelijkheid van de strafrechter. Nu, acht jaar later, reflecteert hij in dit nummer nogmaals op die onafhankelijkheid vanuit zowel nationaal als Europees perspectief. Hij ziet ruimte voor verbetering.
Het OM uit positie? De institutionele positionering van het Openbaar Ministerie ter discussie
Authors: Crijns J.H. (Jan) , Lestrade S.M.A. (Sjarai) , Ouwerkerk J.W. (Jannemieke) , Pitcher K.M. (Kelly)
Published: May 2022

Het OM uit positie? De institutionele positionering van het Openbaar Ministerie ter discussie

In dit artikel wordt in kaart gebracht op welke taakgebieden zich de laatste jaren ontwikkelingen hebben voorgedaan die raken aan de positionering van het OM of in ieder geval aanleiding hebben gegeven die positionering ter discussie te stellen, om vervolgens de vraag op te werpen wat deze ontwikkelingen en discussies zeggen over de (hybride) positionering van het OM en of deze ertoe nopen deze positionering te heroverwegen.
Drama(turgie) van een onafhankelijke rechtspraak
Authors: van der Spek J.H. (Jaap)
Published: May 2022

Drama(turgie) van een onafhankelijke rechtspraak

Een rechtszaak is voor minderjarigen een drama: ze zijn er hoofdrolspeler en figurant tegelijkertijd. De onafhankelijkheid van de rechtspraak, opgevat als dramaturgische gebeurtenis, draagt hieraan bij. De rekwisieten van een onafhankelijke rechtspraak (toga, taalgebruik en rapporten) hebben ook een morele boodschap: de staat neemt een verticale machtsverhouding in ten opzichte van de dader. Als het strafrecht meer horizontale relaties wil aangaan door inzet van het herstelrecht, heeft het nieuwe rekwisieten nodig. Bijvoorbeeld door de rechtszaak aan een tafel te doen.
Geef elke kwetsbare verdachte een advocaat bij het politieverhoor
Authors: Kramer J.R. (Jaantje)
Published: May 2022

Geef elke kwetsbare verdachte een advocaat bij het politieverhoor. Het recht op rechtsbijstand vanuit het perspectief van de kwetsbare verdachte

Voor de kwetsbare aangehouden verdachte wordt van overheidswege een advocaat opgeroepen. Die verdachte kan pas afstand doen van het recht op rechtsbijstand na een advocaat te hebben gesproken. Dat is anders voor de kwetsbare niet-aangehouden verdachte. Die verdachte is zelf verantwoordelijk voor het regelen en betalen van rechtsbijstand, en kan daarvan afstand doen zonder door een advocaat over de gevolgen te zijn ingelicht. Deze bijdrage analyseert dit verschil in rechtsbescherming en de gevolgen daarvan, en geeft aanbevelingen voor de praktijk.
Flow Velocity Gradient of Refined Hydrocarbon and Viscous Fluid in A Single Stage Symmetrical Bifurcated Channel
Authors: Egbo A. Chijioke  , Ahmed M. Hassan  , Opuene D. Ogisobo  , Nama K. Faket  , Onoja I. Valens  , Oluomachukwu P. Onwe
Published: May 2022

A single stage bifurcated system in its wide spectrum of applications in the petroleum and gas processing industry, chemical industry and civil engineering industry, in the distribution and recovery of processed and unprocessed fluid and materials. Considered in this experimental investigation of the impact of a single stage symmetrical bifurcated system on the flow of viscous fluid and refined hydrocarbon to truly establish a relationship between specific dimensions of symmetrical bifurcated flow channels and the physical properties of various classes of fluid samples. Peanut oil and diesel were selected to respectively represent viscous fluid and refined hydrocarbon, as they are allowed to flow through some selected angles of a single stage symmetrical bifurcated channel until designated volumes of each of the fluid samples are recovered into a recovery beaker. Profile of results presented from the experimental study reveals a trend with a sharp negative velocity gradient for small flow time corresponding to smaller

recovery volume and a much lower velocity gradient for relatively higher flow time for higher recovery volume for less viscous and dense diesel oil representing refined hydrocarbon and a more viscous and dense peanut oil represented by the trend with a lower negative velocity gradient. The implication of the results obtained is that bifurcated systems offer flow stability in a continuous flow situation, and also observed from the results is the confirmation of the existence of velocity gradient between opposite wall of the branched channels, which further reveals where the flow state will eventually begin to graduate into turbulence. The study can be extended by investigating the impact of two-stage or multiple level bifurcated network system on flow structure and stability, and how the pressure based on the level of fluid in the reservoir is related to the flow velocity and stability.
Work Motivation, Work Discipline, and Work Environment: Their Effects on Employee Performance at PT TRAD Indonesia
Authors: Imam Sucipto  , Ahmad Gunawan  , Dadang Heri Kusumah
Published: May 2022

PT Trad Indonesia is a Japanese company located in Indonesia. The automotive company is located at Jalan Jababeka II, Kavling C-8, Jababeka Industrial Estate, Cikarang, Bekasi 17530, West Java. However, based on the experience gained and observations made by the researchers, there are employee problems, namely production targets that are difficult to achieve. This research was conducted to find out the effects of work motivation, work discipline, and work environment on employee performance at PT Trad Indonesia. The population consisted of 76 workers. Because the number of members of the population is fewer than 100 people, the researchers took all members of the population as a sample. Thus, the sampling technique used in this study is Non-Probability Sampling with a type of saturated sampling. Multiple Linear Regression Analysis is used to analyze data using SPSS version 22 software. According to the results obtained, partially work motivation, work discipline, and work environment positively affect employee performance. Simultaneously, work motivation, work discipline, and work environment also affect employee performance.
Management Development of Lecturers to Increase Research Quality at Stikom Uyelindo Kupang
Authors: Hasibun Asikin  , Heni  , Yakin A. Asikin
Published: May 2022

This research is motivated by the low quality and research culture of STIKOM Uyelindo Kupang lecturers. The purpose of this study is to determine the management of lecturer development by research institutions, to find out the goals and development programs, and to know the implementation and results of the coaching. The method used in this study is a qualitative descriptive method. The results of this research are: 1) private higher education and training institutions in East Nusa Tenggara have not maximally implemented lecturer development in an effort to improve research quality; 2) the implementation of the training has not been fully implemented by the research institute on the tertiary institution conducting research
The Rosary Devotions of Orani, Bataan and of Hagonóy, Bulacan: A Devotional Link
Authors:   University of Santo Tomas Graduate School, Panganiban Kendrick Ivan
Published: May 2022

This paper aims to present the unifying force brought by a Marian devotion to two towns located in two places with different circumstances in Philippine Church history. In the spiritual geography of the religious orders in the Philippines, the parishes of Bataan were administered by the Dominicans since 1588 while the parishes of Bulacan were administered by majority by the Augustinians since 1572. La Virgen Milagrosa del Rosario del Pueblo de Orani grew as a Marian devotion that has gathered pilgrims in many years. The image was brought to Bataan and eventually completed the triumvirate of Dominican patrons with Abucay being devoted to St. Dominic de Guzman in 1588 and Samal being devoted to St. Catherine of Siena in 1596. When Orani was separated to be an independent parish in 1714, the devotion grew further. Then, between the 1700s to the 1800s, a brown-skinned image of the Virgin and the Child Jesus was discovered along the riverbanks of Hagonóy, Bulacan, under the Augustinians at the other side of the Manila Bay. This image was very similar to Orani's La Virgen Milagrosa, which in turn would be recognized as Nuestra Señora del Santisimo Rosario de Hagonóy. Though a Dominican-propagated devotion, this local rosary devotion and the image grew in this town with various traditions such as Marian poetry and the promotion of the Block Rosary movement. Orani's image would later on be further venerated not only in Bataan but in the neighboring provinces. Though Hagonóy can be found farther East from Bataan and Pampanga, the rosary devotion in this town seemed a visage of the Bataan patroness. By 1942, the fall of Bataan caused Bataeños to travel to Hagonóy and settling in the western barrio of the town. This was eventually named Sto. Rosario in honor of the Virgin of the Rosary. There the Bataeños saw their patroness in the image of the discovered Nuestra Señora del Santisimo Rosario de Hagonóy. The circumstances of the relations between the people of the two towns resulted in the establishment of the parish of Sto. Rosario, Hagonóy in 1952. Further propagation of these two devotions allowed for the recognition of both Marian devotions by their dioceses and by the Holy See. Orani's image was granted a canonical coronation in 1958. Eventually, the church of Orani was granted the titles diocesan shrine in 2004, an affiliate of the Papal Basilica of Santa Maria Maggiore in 2012 and a minor basilica in 2019. The devotion to Nuestra Señora del Santisimo Rosario de Hagonóy, on the other hand, was granted an episcopal coronation also in 2019. The impact of the local Marian devotion in these two towns became a way to unite the Catholic faithful, like a link of the beads of the rosary which identify the country as “Pueblo amante de Maria.”
Comparison two methods- plaque forming unit (PFU) and cell culture infectious dose 50% (CCID50) for potency assay of the national standard measles vaccine
Authors: Thi Mai Huong Nguyen , Van Hung Pham , Thi Thuong Nguyen , Thi Ly Nguyen , Thi Ha Nguyen , Thi Phuong Tran
Published: May 2022

A comparative study of two methods (PFU and CCID50) for potency determination for the national standard candidate measles vaccine was organized at the National Institute for Control of Vaccines and Biologicals (NICVB). Two methods are performed on the groups of candidate measles vaccine derived from AIK-C strain stored at different temperatures: -70oC, 4oC/7 days, 37oC/7 days. The results show that although there is a difference, strong correlation exists between the two methods CCID50 and PFU with R2 = 0.886, r = 0.94, coefficient PFU/ CCID50 = 1.28 equivalent to the ratio PFU: CCID50 = 1:0.78
Apply Mycoflour kit for detection of Mycoplasma in cell lines at National Institute for Control of Vaccines and Biologicals
Authors: Thi Van Quynh Nguyen , Thi Mai Huong Nguyen , Thu Quynh Nguyen , Thi Thu Thuy Nguyen , Khanh Ly Nguyen
Published: May 2022

Control of Mycoplasma in cell culture used in testing is necessary to ensure the accuracy of quality control and vaccine release. Research on fluorescent dyeing process using Mycoplasma detection cell indicators to develop standard operating procedures before routinely used at National Institute for Control of Vaccines and Biologicals (NICVB). Outcome showed that the parameters of the Mycoplasma detection procedure by the Vero cell indicator method using the MycoFlourTM kit at NICVB were optimized for the concentration of Vero cells inoculated into coverslip 10 x104 TB/ml; Wash cells twice with PBS (-)1X and meet the requirements for specificity in cell quality assessment.
RT-PCR test for specific indentification of influenzavirus (A/H5N1) in vaccine
Authors: Thi Dung Luu , Huu Thien Doan , Thi Ly Nguyen , Thi Hong Dinh Nguyen , Thi Tham Be , Hoang Tung Nguyen , Van Hung Pham
Published: May 2022

RT-PCR (Reverse transcription - Polymerase Chain Reaction) is applied to determine the presence of influenza virus A/ H5N1 in vaccine, and to develop an identity process for specific virus strain A/H5N1 in influenza vaccine A/H5N1. Selected samples included: Ivacflu-A/H5N1 vaccine (Institute of Vaccines and Biologicals), Vaxigrip vaccine (Sanofi Pasteur), Influenza virus strain A/ Vietnam/1194/2004(A/H5N1) (NIBSC) was used as positive control; vaccine Varivax (MSD) and DNA/RNA free water was used as negative controls. The results showed that virus strain A/H5N1 was identified as production of RT-PCR that were positive with amplified primer pairs of 2 specific gene sequences of HA whose length 428 and 249 bp. Before starting RT-PCR, it was necessary to eliminate aluminum and the components of RT-PCR reaction included: 5X QIAGEN OneStep RT-PCR Buffer(5µl); dNTP (1µl); forward and reverse primers (1,5 µl); Enzyme (1 µl), H2 O (10 µl), ARN template (5 µl) and thermal cycle of RT- PCR reaction was: 50oC (30 minutes); 95OC (15 minutes); 94OC (30 seconds); 55OC (30 seconds); 72OC (1 minute); 72OC (10 minutes), 45 cycles.
EKSTRAAKSIJALNI TUMORI MOZGA
Authors: Merhemić Zulejha
Published: May 2022

Extraaksijalni tumori mozga su lezije koje ne nastaju iz parenhima mozga i najčešće pomjeraju mozak od kostiju lubanje i proširuju subarahnoidalni prostor. Predstavljaju oko polovine svih intrakranijalnih tumora kod stanovništva Amerike. Meningealni tumori, meningeomi su najčešći tumori mozga, predstavljaju 1/3 svih intrakranijalnih tumora. To su spororastući tumori, vezani bazom za duru. Hemangiopericitomi su nemeningotelialni mezenhimalni tumori. Drugi najčešći extraaksijalni tumori su tumori kranijalnih živaca: švanomi i neurofibromi. Tumori hipofize, kraniofaringeomi, hordomi i tumori epifize, također, pripadaju ekstraaksijalnim tumorima. Poznavanje radiološke anatomije i anatomskih odnosa lezije su od izuzetnog značaja za postavljanje dijagnoze i planiranje tretmana. Magnetna rezonanca (MR) je „zlatni standard“ zbog svojih multiplanarnih i multiparametarskih mogućnosti, te tkivne karakterizacije. Kompjuterska tomografija (CT) omogućuje analizu kosti, te prisustvo kalcifikata unutar lezije, ali se koristi u onim slučajevima kod kojih je MRI pregled kontraindiciran. Prikazat ćemo MRI i CT karakteristike ekstraaksijalnih tumora mozga i njihov klinički značaj.
KOMPARACIJA TRODIMENZIONALNE KONFORMALNE RADIOTERAPIJE (3DCRT) I VOLUMETRIJSKI-MODULIRANE LUČNE TERAPIJE (VMAT-RA) U POSTOPERATIVNOM TRETMANU GLIOBLASTOMA
Authors: Trokić Danijela , Jaroš Dražan , Marošević Goran , Arsovski Oliver , Drljača Dušan
Published: May 2022

Cilj. Uporediti dozimetrijske parametre trodimenzionalne konformalne radioterapije (3DCRT) i volumetrijski modulirane lučne radioterapije (VMAT-RA) kod postoperativnog tretmana glioblastoma (GBM). Metode: Retrospektivno istraživanje uključilo je pacijente s dijagnozom GBM, liječene u periodu od septembra 2014. do januara 2017. u Centru za radioterapiju Banja Luka. Za svakog pacijenta pojedinačno urađena je simulacija kompjuteriziranom tomografijom (CT) i registracija postoperativne magnetne rezonance (MRI). Delineacija ciljnog volumena (PTV) i organa od rizika (OAR) urađena je prema registriranom MRI i ESTRO-ACROP preporukama. Tretman je proveden 3DCRT radioterapijom konkomitantno uz temozolomid. Naknadno je za svakog pacijenta urađen VMAT-RA plan s optimizacionim parametrima koji zadovoljavaju dozne limite OAR. Dodatne optimizacije nisu rađene, jer pacijenti nisu planirani da se zrače VMAT tehnikom. Kontrolnu grupu činili su 3DCRT planovi, a VMAT-RA eksperimentalnu grupu. Propisana je doza TD 54 – 60 Gy. Za obje tehnike zračenja su komparirani dozimetrijski parametri u dozno-volumnom histogramu (DVH). Shapiro-Wilk-ov test pokazao je asimetričnu distribuciju, značajnost razlika je utvrđena Wilcoxonovim testom predznaka rangova. Sve p vrijednosti manje od 0.05 smatrane su statistički značajnim. Rezultati: Pokrivenost dozom 98%, 95%, 50% i 2% volumena PTV tehnikom 3DCRT iznosila je 95.36±1.08, 96.88±0.88, 100.74±1.08 i 104.76±1.34, a za RA 96.53±0.86, 97.63±0.65, 100.05±0.15 i 102.47±0.55 redom, statistička značajnost p=0.007, 0.022, n.s i 0.005. Indeks homogenosti (HI) za 3DCRT je 0.09±0.02, za RA 0.06±0.01, p=0.005. Indeks konformalnosti (CI) za 3DCRT je 0.98±0.01, za RA 0,98±0,02, p=n.s. Doza na moždano stablo, ipsilateralni i kontralteralni optički nerv i hijazmu bila je nešto veća za RA, ali bez statističke značajnosti. Volumen mozga V50 bio je značajno manji kod RA. Zaključak: Primjena VMAT- RA tehnike bez dodatnih dozimetrijskih optimizacija u odnosu na 3DCRT rezultira boljom pokrivenosti PTV-a dozom i boljom homogenosti doze unutar PTV-a, ali bez značajne razlike u dozi koju primaju OAR.
Democracy Avoidance in Tax Lawmaking
Authors: Wallace Clinton
Published: May 2022

The Tax Cuts and Jobs Act was the most significant tax law in more than three decades, but the strategy for getting it enacted included a variety of maneuvers to avoid public scrutiny. As a result, many taxpayers did not know how they would be affected until they filed their own tax returns more than a year later. This Article identifies this lack of transparency as part of a persistent pathology of avoiding and constraining democratic inputs and responsiveness in U.S. federal tax lawmaking. Indeed, some scholars and policymakers have sought to channel tax lawmaking away from democratically grounded decisions and towards prescribed outcomes, justifying these moves with strands of public choice theory that are expressly critical of democratic decision making. I critique this democracy avoidance approach to tax lawmaking, and make the case that tax law should be a product of mechanisms that provide greater transparency, accountability and responsiveness to advance democratic legitimacy.

I propose four reforms to tax lawmaking in the U.S. Congress to make resulting tax laws more democratically legitimate. One proposal is to require Congress to consider (and publicize) precisely how a proposed change in tax law is expected to affect different typical taxpayers, including taxpayers from each congressional district. This would allow actual taxpayers observing the lawmaking process to anticipate their treatment under a proposed law and in turn demand greater responsiveness to their real interests from their representatives. Other proposals build on this approach, calling for transparency as to the reasons why legislators support particular provisions and a radical—but, I argue, entirely achievable—reworking of the types of analysis produced in the federal tax legislative process for consumption by non-experts.
DIDÁTICAS DA GEOGRAFIA:
Authors: Carneiro Rosalvo Nobre
Published: May 2022

Em perspectiva histórica, a didática da Geografia se revela como agir instrumental pela intencionalidade do ensino, mediante a execução de um plano e a eleição dos meios adequados pelo professor. Neste contexto, propõe-se uma didática do agir comunicativo cujo telos é a construção de entendimentos mediados por relações intersubjetivas. Para tanto, revisa-se a literatura pertinente sobre as geografias escolares progressistas e as geografias escolares críticas. Constata-se que estas didáticas se aproximam do modelo de racionalidade instrumental. Os caminhos abertos por uma pedagogia geográfica do agir orientado para o entendimento mútuo se revelam promissores para o desenvolvimento de princípios éticos e morais universais. Além disso, a autonomia e a emancipação humana e social são buscadas mediante a centralidade da situação ideal de fala.
A METRÓPOLE FORTALEZA-CE TURISTIFICADA
Authors: Dias Débora Ferreira Freire , Coriolano Luzia Neide Menezes Teixeira
Published: May 2022

Fortaleza, metrópole brasileira, inserida no contexto da globalização, mundialização e reestruturação do capital se moderniza via processo de implementação de atividades turísticas tornando a cidade turistificada, espetacularizada e espraiada na zona litorânea, espaço do turismo do Ceará. O texto objetiva compreender os processos de turistificação e espraiamento das atividades turísticas nos municípios do litoral cearense. Respalda-se na revisão de literatura que fundamenta o exercício de teorização do empírico. Adota-se método dialético de visão crítica, evita dicotomias, faz ver as relações na apreensão do objeto, entendido como totalidade.  Constata-se que o turismo se espraia da metrópole para o litoral cearense ocasionando arranjos espaciais e negócios turísticos apropriando-se do espaço e de recursos econômicos.
OS ESPAÇOS SAGRADOS E PROFANOS DA FESTA DO SENHOR DO BONFIM: UM ESTUDO DE CASO NA CIDADE DE BOCAIÚVA-MG
Authors: Batista Ramony Pereira , Palhares Ricardo Henrique
Published: May 2022

A abordagem geográfica da religião parte do entendimento desta como parte integrante da cultura e de ser uma manifestação espacial. O Catolicismo é parte constituinte da história, da formação social, cultural e religiosa dos brasileiros, porém, sua prática possui características singulares e com forte sincretismo. As festas devocionais são traços do catolicismo português e aqui é marcado por fortes tradições populares em seus rituais e espaços. O objetivo desse estudo é analisar o estabelecimento dos espaços sagrados, fixos e móveis, e do espaço profano nas festividades em honra ao Senhor do Bonfim, na cidade de Bocaiúva, no Norte de Minas Gerais. Os procedimentos teórico-metodológicos estão ancorados na literatura especializada da Geografia da Religião, bem como visitas às festividades na área de estudo. Afirma-se que a religião é um fator importante na construção e cotidiano das cidades, especialmente as médias e pequenas.
NutrinPrice: uma plataforma colaborativa para apoiar a seleção de produtos alimentícios
Authors: Alves Rian das Dores , David José Maria , Braga Regina Maciel , Siqueira Kennya , Stroele Victor , Barbosa Guilherme , da Costa João Pedro de S. J. , da Silva Izaque Esteves
Published: May 2022

Parte da população apresenta deficiência nutricional devido às más condições de alimentação. O custo dos produtos alimentícios e o desconhecimento dos nutrientes são fatores relevantes para a má nutrição. Selecionar produtos ricos nutricionalmente e com baixo custo são desafios. Este trabalho propõe uma plataforma para captação, organização e visualização de dados e preços dos produtos consumidos. A solução busca, por meio da colaboração de usuários e supermercados, prover informações referentes aos produtos, de modo a apoiar a seleção desses produtos. Como resultado, buscamos mitigar o problema da má nutrição na sociedade. Um estudo de viabilidade foi conduzido a partir dos dados capturados.
Utilizando a Percepção Sócio-Cognitiva para Analisar Experiência Feminina em Hackathons
Authors: Almeida Luciana A. , de Souza Cleidson R. B.
Published: May 2022

Hackathons são eventos colaborativos de curta duração em que pequenas equipes tem o objetivo de criar, desenvolver e apresentar solução para um problema. Eles estão se tornando cada vez mais populares em todo o mundo. Entretanto, o interesse de mulheres nestes eventos ainda é baixo. O objetivo deste trabalho é investigar sob uma perspectiva sócio-cognitiva como as experiências femininas em hackathons são percebidas. A autoetnografia é o método utilizado para a sistematização da experiência da primeira autora como participante de dois hackathons. Os resultados sugerem que os formatos dos eventos e as experiências de colaboração com suas equipes podem afetar as crenças de autoeficácia e expectativas de resultados. Estas crenças podem influenciar na percepção das mulheres sobre seu potencial de atuação no hackathon e no mercado de trabalho.
Uma Proposta de Comunidade de Prática a partir da Experiência de Uso de Técnicas de Design Thinking no Desenvolvimento de Software
Authors: Parizi Rafael , Hanauer Lucas , Marczak Sabrina , Conte Tayana
Published: May 2022

Diversas técnicas de Design Thinking (DT) têm sido usadas no desenvolvimento de software para fomentar a empatia, a colaboração, a criatividade, e auxiliar as equipes a entender as necessidades do usuário, gerar várias ideias, prototipar e selecionar a solução que atenda tais necessidades. Portanto, neste universo de várias técnicas, selecionar quais delas utilizar para o desenvolvimento de software configura-se como um problema de tomada de decisão. Contudo, há uma ausência de recursos que disponibilizem espaços para que os profissionais de TI que usam o DT possam compartilhar suas experiências, ou possam coletar informações que auxiliem na tomada de decisão de quais técnicas usar. Neste sentido, inspirados no modelo Spotify de organização de equipes, este artigo apresenta insights de uma proposta que visa promover uma comunidade colaborativa a partir de experiências de profissionais com o uso de técnicas de DT. Dessa forma, este artigo busca contribuir com a seleção de técnicas DT para o desenvolvimento de software.
Como definir um laboratorio de inovação em governo? Um estudo de caso de uma iniciativa na área de controle externo
Authors: Agostinho Matheus Cavalcanti , Valença George
Published: May 2022

Na última década, os laboratórios de inovação têm se tornado cada vez mais frequentes e importantes para alavancar a inovação em todas as esferas e áreas de atuação do setor público brasileiro. No entanto, os relatos sobre o processo de desenvolvimento desses laboratórios ainda são escassos e superficiais. Neste artigo, apresentamos um estudo de caso descritivo do Prisma Lab, laboratório de inovação do Tribunal de Contas do Estado de Pernambuco (TCE-PE). Através de uma cooperação técnica com a academia, o TCE-PE pôde estruturar a o seu laboratório, que adota um modelo de inovação aberta para enfrentar os variados desafios da instituição, ampliar os seus resultados e legitimar sua relevância para a sociedade.
New Trends of Optical Measurements
Authors: Angelsky Oleg , Maksymyak Peter , Zenkova Claudia , Ushenko Olexander , Zheng Jun
Published: May 2022

Some of the achievements of modern optical metrology are offered for the reader at this chapter. Optical testing methods have always attracted by their important advantages: distance, non-destructive impact on the test object and, of course, high accuracy. So, using of polarization optics approach, the authors were able to implement the methods for controlling the surface roughness for the moving surface with the measurement accuracy of 10 angstroms. It has become possible to make a breakthrough in the basic methods of measurements from the nano to the femto or pico units of the measured quantity value over the past decades. Control of nano (micro) particle motion by an optical field and their use for testing complex optical fields; ultra-precise determination of the optical parameters of both solid and liquid and gas-like substances by optical methods; by interference methods and many other, are proposed for consideration here. Some biomedical applications are also offered for reader’s familiarization. Particularly, the results of 3D Stokes-polarimetric mapping of microscopic biological images with digital holographic reproduction of layer-by-layer ellipticity polarization maps in differential diagnosis of benign and malignant tumors with different degrees of differentiation are presented. The authors have shown that using of polarization-holographic measurements in biomedical applications makes it possible to obtain a reliable diagnostic of pathological states both of biological fluids and solid-state objects.
Status of World’s Unique Animal Genetic Resource of Ladakh
Authors: Din Sheikh Feroz
Published: May 2022

Ladakh is the only typical cold arid zone of our country with extreme climate and hostile condition, the area makes its flora and fauna a unique one and distinct from rest of the country. Around 60% of the farmers of Ladakh are Pastoralist and 40% of the farmers are agriculturist and the majority of the economic income comes from animal rearing in Ladakh. It has some of the world’s best animal genetic resource in the form of Changthangi Pashmina goats, Changthangi Sheep, Malra Goat, Malluk and Purig Sheep, Semi domesticated Yak and its crosses, Bactrian (Double Humped Camel) Zanskari horse, Ladakhi Cattle and Changthangi Dog. All these livestock contributes a lot to the income of the farmers of Ladakh especially the Changthang nomads who are completely dependent on livestock rearing. The livestock in Changthang is reared on extensive system on high altitude pastureland. During the past few decades these unique germplasms are facing several threats for its eco-friendly existence with the human populations. These threats and constraints are figured with possible recommendation and solution in the present study. Ladakh has been deprived of basic research facilities in animal science sector for so many years due to which this unique genetic resources are declining in terms of numbers as well as in production. Another reason is shifting of Ladakh economy from agro pastoralist to tourism business. If necessary steps are not taken immediately a time will reach that all this precious animal will be lost forever. The present article describes the present status and critical issues pertaining to animal genetic resource of Ladakh.
Honey as a Natural Product Worthy of Re-Consideration in Treating MRSA Wound Infections
Authors: Ayefoumi Adinortey Cynthia , Wilson Michael , Kojo Kwofie Samuel
Published: May 2022

The use of antibiotics to treat bacterial infections have largely been successful. However, the misuse and overuse of these precious drugs have led to the development of bacterial resistance and this seems to have jeopardized their effectiveness. Many antibiotics that hitherto were seen as “miraculous drugs”, have witnessed a low efficacy and this has threatened the life of humanity as never before. The rapid emergence of antibiotic resistance in bacteria is the major cause of this sad development. One such superbug is methicillin-resistant Staphylococcus aureus (MRSA). MRSA is a general problem in most healthcare centers with a reported astronomical incidence of invasive MRSA infections causing death. Honey, a natural product, popular for its antibacterial activity is increasingly being used owing to its reported antibiotic potential against ‘stubborn’ bacteria. This review discusses the fact that though honey is an ancient remedy, it is still relevant and its application in modern medicine for the treatment of chronically infected wounds caused by MRSA should be re-visited. Furthermore, the in vitro antibacterial and antibiofilm activities of medical-grade honey on S. aureus infections and challenges encountered by Researchers in developing honey, into an acceptable medical, therapeutic antibacterial agent for wound care have also been highlighted.