bluuebunny/crossref_metadata_2025 huggingface dataset:
Higher Omicron JN.1 Coronavirus Transmission due to Unique 17MPLF Spike Insertion compensating 24LPP, 69HV, 145Y, 211N and 483V deletions in the spike
Authors: CHAKRABORTY ASIT KUMAR
Published: January 2024

The COVID-19 Spike protein 24LPP, 69HV, 143VYY, 156FR, 212L deletions, 215EPE and 249RWMD insertions were very well characterized. Changes in spike likely select RBD in a favorable 3-D structure to interact with ACE-2 receptor of human cells for coronavirus entry. Our goal is to characterize the newly spreading JN.1 subvariant and related omicron coronaviruses. BLASTP search found a 17MPLF four amino acid insertion in omicron BA.2.86 subvariant and its precedent JN.1 subvariant which had unique L452S (L455 in Wuhan) spike mutation. The JN.1 variant also contained 2375SGF deletion in ORF1ab, 24LPP, 69HV, 145Y, 211N (208N in BA.2) and 483V (480V in BA.2) deletions in the spike, 31ERS deletion in N-protein and 26nt deletion in 3’-UTR (NC_045512.2). Many unique JN.1 spike mutations (242N = H249N, 261D = A268D, 352T = K360T, 400K = R407K, 442H = P449H, 449W = L456W, 474K = N485K, 480K = A488K and 566V = A574V) might be also important. The BLASTN search with insertion oligo found over 3895 JN.1 related sequences in the NCBI Database and were well distributed in America and Europe but more monopartite JN.1 sequences deposited from Europe. Although, JN.1 acquired the 69HV deletion lately but did not generated from BA.4 or BA.5 lineages and it was solely generated from BA.2.86 variant. Swiss-Model detected a wing structure with basic amino acid in the middle of tripartite spike of JN.1 and important ACE-2 first interacting surface amino acids were changed. The small M protein of JN.1 had D3H, A63T and A104V mutations but Swiss Model showed no gross change in 3-D structure. Further, four JN.1 specific ORF1ab polyprotein mutations were detected: T170I mutation in nsp1 as well as D1600N, K1973R mutations in nsp3 protease and R3821K mutation in nsp6. Astonishingly, after a long journey of XBB.1.5.1 to XBB.1.5.100 subvariants spread, a sudden five amino acids deletion (176EGKEG and180EGKQG in Wuhan) in the spike of XBB.1.5.103 subvariant was found. The ORF8 immune-regulatory protein expression was abolished in all XBB.1 subvariants including XBB.1.5.103 and XBB.1.16.23 as expected due to termination codon mutations (AAA = TAA, CAA = TAA, GGA = TGA). But such ORF8 gene mutation (GGA = TGA) was also found in ongoing dominated JD.1.1, FL.1.5.1, HV.1 and EG.5.1.1 subvariants, derived from XBB.1 lineage. The FL.1.5.1 variant also has 82GHV deletion instead 82GHVMV in the nsp1 protein as well as a 27nt deletion (27887 5’-aac gaa cat gaa att tct tgt ttt ctt-3’) in the ORF7a gene. Partial or no expression of nsp1, ORF7a and ORF8 regulatory proteins cause coronavirus more immune deficient and less pathogenic. The spread of JN.1 has sent an alarm among health officials worldwide. It is worthwhile to see if JN.1 coronavirus goes nsp1 or OR7a deletion and ORF8 termination codon mutation with time lowering pathogenicity.
Determination of the form of a spiral spring in a free state
Authors: Pylypaka Serhii , Volina Tetiana , Hropost Vyacheslav , Babka Vitaliy , Hryshchenko Iryna
Published: January 2024

The object of research. This article deals with a spiral spring made of tape material with a rectilinear cross-section.

Investigated problem. If one end of a metal ruler is pinched, and a certain force is applied to the other end, it will bend under the action of the generated moment. The magnitude of the moment depends on the applied force and the length of the ruler. Therefore, the amount of deflection will increase with the increase of these parameters, and the shape of the ruler may take the spiral form. After the termination of the external load, the ruler will regain its original shape, that is, it will become straight. However, such spiral springs do not exist in practice. For compact sizes, the spring in its free state also has a spiral shape. In this regard, the purpose of the study is to find the elastic axis of a tape spiral spring in a free state, which under the action of a concentrated force takes a given shape.

The main scientific results. The shape of the spiral spring in the free state is determined, which under the action of the applied force acquires the desired shape, which does not lead to the occurrence of frictional forces between adjacent coils.

The area of practical use of research results. Spiral springs are widely used. One example is mechanical clock movements and measuring devices, in which the determination of indicators depends on the applied force that "unwinds" or "twists" the spring.

Innovative technological product. The paper calculates the elastic axis of a spiral spring in a free state according to its given final shape, taking into account the moment that arises as a result of the applied force at the end of the spring. For this, the nonlinear theory of absolutely elastic bending using the methods of differential geometry of curved lines as a function of the own length of the arc of the spring axis is applied.

The scope of application of the innovative technological product. The results obtained in the study can be used in the manufacture of spiral springs for various purposes, as well as for the accumulation of potential energy in the absence of other sources
Design Considerations for Facilitating Equitable Participation in an Ethical Data Science Course for High School Students
Authors: Register Jordan
Published: January 2024

The emergence of data science, Big Data Analytics, and other related methodologies have resulted in differential outcomes for people situated differently in society. Exacerbating these effects is the privilege hazard (D’Ignazio & Klein, 2020) that occurs when teams of data scientists are composed primarily of individuals from privileged backgrounds. Therefore, the purpose of this article is to understand how educators may support students from different backgrounds (both relatively privileged and marginalized) to participate equitably and meaningfully in ethical data science discussions in order to safeguard against the privilege hazard. To do this, we draw on the literature regarding STEM identity formation, use Cobb and Yackel’s (1996) framework for analyzing social norms for discourse in inquiry-based classrooms, and draw on Hodge and Cobb’s Cultural Participation Orientation towards developing an inclusive classroom environment. Finally, we describe the course design elements (task structures, participation structures, and discursive moves) that supported students’ equitable participation in ethical data science discussions (Sandoval, 2004).
Educational Aspirations of Diverse Groups among Undergraduate Statistics Majors
Authors: Lorah Julie , Miller Angie
Published: January 2024

Understanding the educational aspirations of diverse groups among statistics majors provides insight into the discipline of statistics. This study utilizes multi-institution data from the 2019 and 2020 administrations of the National Survey of Student Engagement (NSSE) to explore educational aspirations for statistics majors through comparisons to other major types as well as among gender identity and race/ethnicity in a sample of 225,892 seniors, including 521 majoring in statistics. Preliminary results from a series of chi-squared analyses suggest that while other STEM majors are more likely to aspire for doctoral or professional degrees, statistics majors are more likely to aspire for a master’s degree. However, among the statistics majors there were no significant differences in educational aspiration by gender identity and race/ethnicity.
The Role of Technology in Enhancing Urban Mathematics Education
Authors: Young Jamaal Rashad
Published: January 2024

The integration of technology in urban mathematics education has emerged as a promising approach to address educational disparities and foster engaging learning environments. With the widespread availability of technology infrastructure in urban schools, there is a growing focus on leveraging digital tools and resources to enhance mathematics learning outcomes. This editorial examines the impact of technology on urban mathematics education, exploring its potential to bridge opportunity gaps and promote inclusivity. Drawing on current research and best practices, we highlight the benefits and challenges of technology integration, emphasizing the importance of equitable access, teacher professional development, and tailored instructional approaches. The editorial underscores the need for collaborative efforts among stakeholders to advocate for increased funding and support for technology initiatives in urban schools. By embracing innovative practices such as educational apps, virtual reality, and online collaborative projects, educators can create dynamic learning environments that empower students to excel in mathematics. The ongoing dialogue and efforts surrounding the role of technology in urban mathematics education are critical for achieving educational equity and excellence for all students. As technology continues to evolve, it remains imperative for educators and policymakers to prioritize effective technology integration strategies that cater to the diverse needs of urban learners.
Theoretical Prediction for Thermo Elastic Properties of Nano CdSe (Rock Salt Phase)
Authors: Srivastava Shivam , Singh Prachi , Pandey Anjani K. , Dixit Chandra K. , Pandey Brijesh K
Published: January 2024

In this study, we investigated the thermoelastic properties of nano CdSe (rock salt phase) under varying pressure conditions using three different equations of state (EOSs): the Birch-Murnaghan 3rd EOS, the modified Lenard Jones EOS, and the Vinet-Rydberg EOS. Our objective was to determine whether these EOSs could accurately predict the behavior of nanomaterials by comparing the calculated results with experimental data. The pressure values obtained at different V/V0 ratios were found to be in good agreement with experimental data, suggesting that these EOSs are reliable for the calculation of nanomaterials properties. Additionally, we established the Gruneisen parameter, bulk modulus, and first pressure derivative of the bulk modulus to further characterize the behavior of nano CdSe.
Pharmaceutical Waste: Risks & Challenges Faced by Aquatic Ecosystem
Authors: Pandey Ayoni , Rai Nivedita , Tripathi Shivendra Mani , Mishra Sudhanshu
Published: January 2024

Pharmaceutical industries are experiencing a steady increase in both their numbers and demands, leading to a significant rise in the amount of waste they generate. This waste comprises various components such as organic compounds, excipients, and plastic containers. Unfortunately, a major portion of this waste is discharged into aquatic bodies through pipes, eventually reaching canal systems and ultimately the seas. This practice poses a severe threat to aquatic life, as it significantly impacts their habitat in a hazardous manner. One of the primary deleterious effects caused by pharmaceutical waste discharge is the elevation of the Biological Oxygen Demand (BOD) in the affected aquatic areas. This increase in BOD results in reduced oxygen availability for aquatic creatures, leading to mortality and ultimately causing a disruption in the natural balance of the ecosystem. Moreover, the accumulation of organic compounds from pharmaceutical waste leads to eutrophication, which accelerates the aging process of lakes, ultimately converting them into land. Another harmful consequence is biomagnification, wherein the concentration of toxicants increases as they move up the food chain through successive trophic levels. The continuous contamination of aquatic ecosystems by industrial waste is exacerbating the degradation of these fragile environments. However, the growing recognition of this issue has prompted research and implementation of various water treatment methods. These methods aim to mitigate the degradation rate and protect aquatic ecosystems from further harm. By employing advanced treatment techniques, it is possible to reduce the negative impact of pharmaceutical waste discharge and preserve the integrity of aquatic ecosystems. Efforts must be made to raise awareness among pharmaceutical industries about the importance of responsible waste management. By adopting sustainable practices and investing in environmentally friendly technologies, such as improved waste disposal systems and more efficient water treatment methods, the industry can significantly reduce its ecological footprint. Collaboration between regulatory bodies, environmental organizations, and pharmaceutical companies is essential to address this pressing issue effectively. With concerted efforts and a collective commitment to environmental stewardship, it is possible to mitigate the detrimental effects of pharmaceutical waste on aquatic ecosystems and safeguard the future of our planet's delicate aquatic habitats.
Solar Cooker Carbon Mitigation Potential and Load Capacity: Identification, Analysis, and Utility of the Objective Parameters Derivable from Cooker Opto-Thermal Ratio (COR)
Authors: Panja P S , Jamal Md. Rahbar , Samdarshi S K , Singh Mandeep , Ansari Md. Aaquib Ullah
Published: January 2024

Thermal performance parameters (TPPs) are used to rate the thermal performance of a solar cooker by researchers/developers and the objective parameters (OPs) to assist in the evaluation of the utility a solar cooker by users. Few researchers have utilised the correlation between TPP and OPs to facilitate the end users' decision-making with regard to the utility of a cooker for the intended purpose of successfully and satisfactorily completing cooking. In this review paper, some of the performance parameters and the related test procedures have been reviewed. Further an attempt has been made to identify and propose some new and useful objective parameters such as solar cooker load capacity (mmax) and solar cooker carbon mitigation potential (mco2), which will help the user in deciding about the load capacity (specific mass) limit and quantifying its contribution as a clean cooking device (one of the goals of UN, SDG2015), respectively.
Effect of Waste Pomegranate Peels Biodiesel on Performance and Emission Analysis of Diesel Engine
Authors: Yadav Santosh Kumar , Kumar Devesh , Suraj  , Singh Suraj , Kumar Priyankesh , Singh Varun Kumar
Published: January 2024

The effect of conventional fuels has been investigated for its sustainable effect on the progress of power generation, the industrial sector, agriculture, and other related needs. In daily routine, the diesel engine has been identified as an essential part of the power and energy sectors. Diesel engine exhaust emissions have negatively impacted living organisms' health. Biodiesel have been identified as a sustainable fuel source that can replace traditional petroleum-based diesel fuel. The present work is to investigate using pomegranate peels to extract the pomegranate peel oil by Soxhlet apparatus and then convert it into biodiesel with the help of the transesterification process. Further, three different blending ratio mixtures with the help of pomegranate peel biodiesel (PPBD) were made on a volume basis, named PPBD 0 (FD 100%), PPBD 10 (10% biodiesel + 90% FD), and PPBD 20 (20% biodiesel + 80% FD), to check their performance and emission analysis on a single cylinder, four-stroke diesel engine. In diesel engines, the study investigated the system's performance concerning brake thermal efficiency (BTE) and brake-specific fuel consumption (BSFC). The study analyzed various emissions, including carbon monoxide (CO), hydrocarbons (HC), carbon dioxide (CO2), and nitrogen dioxide (NOx), using a gas analyzer. The study results indicate that PPBD 20 is the most effective blending mixture in performance and emission reduction, making this fuel a potential substitute for fossil diesel.
ORGANISMS RESPONSIBLE FOR TOTAL KNEE PROSTHETIC JOINT INFECTION: A SAUDITERTIARY CENTER 10-YEAR-EXPERIENCE
Authors:   Orthopedic Consultant, Department of Orthopedic Surgery, King Abdul-Aziz Medical City, Jeddah, Saudi Arabia., Al Dakhil Mohammed , A. Alsubaihi Amr ,   Orthopedic Consultant, Department of Orthopedic Surgery, King AbdullahMedicalComplex-Jeddah, Saudi Arabia., A. Basaqr Abdulaziz ,   Orthopedic Consultant Department of Orthopedic Surgery, Dr. Samir Abbas Hospital, Jeddah, Saudi Arabia., Mahfoudh Abdulmajeed ,   MD, Orthopedic Department, King Abdul-Aziz Medical City, Jeddah, Saudi Arabia., M. Al Dakhil Abdulaziz ,   MBBS, Saudi board of orthopedics (SBO), Prince Sultan Medical City, Riyadh, Saudi Arabia.
Published: January 2024

Background: Total Knee arthroplasty (TKA) is a standard procedure to treat end-stage knee osteoarthritis. As with any surgery, complications may arise, and one of the common complications reported from knee replacement procedures is infection. In this study, we aimed to retrospectively determine the prevalence of the infections pathogens following TKA and identify the most common microorganisms involved in infections in knee arthroplasty. Methods: Data were gathered from archived medical files using a retrospective descriptive study methodology. The current study included patients who underwent total knee arthroplasty and experienced infections between 2007 and 2017 at King Abdul-Aziz Medical City (KAMC), Jeddah, Saudi Arabia. Results: Out of 56 patients, almost half were hypertensive (57.1%) and diabetic (46.4%). 51.8% of patients had bilateral TKA. Among the patients, a third (41.8%)had pain the primary organism identified was Staphylococcus (44.65%), and 20% of cases involved co-infection with another organism. 16% of patients had methicillin-resistant Staphylococcus aureus. Infections with pseudomonas, brucellosis, and tuberculosis were also present in 17.9%, 3.6%, and 1.8% of the patients, respectively. Conclusion: Staphylococci were identified as the primary organism responsible for prostheticknee infection in KAMC patients. We recommend a focus on staphylococci in both prophylactic and empirical antibiotic treatments. Additional multicenter studies examining larger sample sizes are required to identify other factors influencingProsthetic Joint Infection (PJI), including obtaining information on the patients antimicrobial sensitivity profiles and geographic factors.
A PROSPECTIVE STUDY ON AWARENESS OF COVID-19 VACCINATION AMONG PATIENTS WITH DIFFERENT TYPES OF CANCER
Authors:   Department of Pharmacy Practice, Malla Reddy Pharmacy College, Hyderabad, Telangana, India., Zaineb Kubra Hussaini Syeda , Jilla Swapna ,   MBBS, DNB Radiation Oncologist, Malla Reddy Narayana Cancer Hospital, Hyderabad, Telangana, India., Palavardhan Peddapalegani ,   Ph.D., Research Scholar, Department of Statistics, Sri Venkateshwara University, Tirupati, Andhra Pradesh, India., Anusha Jagillapuram ,   Pharm.D (Doctor of Pharmacy), Malla Reddy Pharmacy College, Hyderabad, Telangana, India., Chandana Kajjam ,   Ph.D., Research Scholar, Department of Statistics, Sri Venkateshwara University, Tirupati, Andhra Pradesh, India., Prathyusha Kakadi ,   Department of Pharmacy Practice, Malla Reddy Pharmacy College, Hyderabad, Telangana, India.
Published: January 2024

Background: Cancer is the major leading cause of death. People with cancer haveweakened immune system hence they are more vulnerable to Covid-19 infection. Vaccination is the best way to prevent Covid-19 infection and it mainly prevents community transmission.Covishield, Covaxin& Sputnik-V are type of vaccines available to produce immunity againstSARS-COV-2virus. Objective: Toassesstheawarenessofcovid-19vaccinationamongpatientswithdifferenttypes ofcancer. Method: It was prospective, Observational study conducted in Total 200 cancer patients from single tertiary care hospital were asked to complete a questionnaire designed to assess their knowledge about the vaccine, their readiness to be vaccinated and the determinants of their decision. Based onType of cancer the study population was categorized. The study population was interviewedafter obtaining Informed Consent Form for information about their awareness on Covid-19Vaccination. Results and Discussion: In our study population, it was observed that Femalepatients (67%) were higher than Male patients (33%). A total of 86% patients considered themselvesmore vulnerable to Covid-19 than the general population. Television, radio, Newspaper were major sources of information about the vaccine. A total of 65% of the patients were ready to be vaccinated and 9% refused the vaccine.The main reason for refusal was incompatibility with patients disease or treatment. Conclusion: In the present study it is observed most of the patients have accepted theCovid-19vaccination.Inthisstudymorethanhalfwerevaccinatedwithongoingactivecancertreatment.TheVulnerabilitytoCovid-19infectioninthesepatientsarealsopredominance.
COMPARATIVE ANALYSIS OF REGIONAL TRADE BLOCS
Authors: Dahikar Karunya
Published: January 2024

This research paper investigates the impact of regional trade blocs (RTBs) on global trade and economic growth, adopting a comparative perspective. Regional trade agreements (RTAs) have gained significant prominence in the global economy due to their role in promoting trade liberalization and economic integration among member nations. This study aims to assess the potential for multilateral liberalization within these blocs and examines how political and ideological differences influence the effectiveness of RTBs. Additionally, it explores the consequences of the proliferation of RTAs on international trade dynamics and their broader economic implications. The analysis begins by examining the effects of RTBs on global trade. The study compares the trade performance of RTB member countries with non-member countries to assess the extent to which RTBs contribute to trade expansion. Furthermore, the research investigates the impact of RTBs on economic growth. The economic integration fostered by RTBs can lead to increased investment flows, technology transfer, and productivity gains. It considers the potential spillover effects of RTBs on non-member countries, as increased regional integration may create both opportunities and challenges for economies outside the bloc. The analysis also delves into the complexities of multilateral liberalization within RTBs. While RTBs aim to promote trade liberalization among member countries, the presence of political and ideological differences can hinder the achievement of comprehensive agreements. The study explores the challenges faced by RTBs in reaching consensus on sensitive issues such as agriculture, intellectual property rights, and services trade. It examines the role of political dynamics and power asymmetries within RTBs in shaping the outcomes of negotiations.
SUSTAINABLE DEVELOPMENT IN UTTARAKHANDS PULP AND PAPER INDUSTRY: A COMPREHENSIVE RESEARCH ANALYSIS
Authors: Bisht Ridhi
Published: January 2024

This research paper delves into the Pulp and Paper Industry in Uttarakhand, exploring its historical development, technological advancements, environmental impact, regulatory landscape, and proposed strategies for sustainable development. Uttarakhands rich forest resources make it a significant contributor to the paper manufacturing sector, with a historical reliance on traditional manufacturing processes. However, the industry has undergone transformative changes to adopt sustainable practices, such as high dependence on biomass residues for energy. Technological advancements, including mechanical and chemical pulping innovations, recycled fiber processing, digital printing, nanotechnology applications, and energy-efficient processes, have played a pivotal role in improving environmental sustainability. The environmental impact, including deforestation, air and water pollution, and greenhouse gas emissions, is examined, emphasizing the need for sustainable forestry practices and clean energy sources. The paper also discusses relevant regulations and policies affecting the industry in Uttarakhand, along with existing challenges and opportunities. The research concludes with proposed solutions and strategies for achieving sustainable development in the regions Pulp and Paper Industry.
AORTIC DISSECTION MISDIAGNOSED AS A HYPERTENSIVE CRISIS: A CASE REPORT
Authors:   Assistant Professor, Department of General Medicine, Noida International Institute of Medical Sciences, Gautam Budh Nagar, Uttar Pradesh, India., Ratna Sumol , Choudhary Vipin ,   Senior Resident, Department of General Medicine, Noida International Institute of Medical Sciences, Gautam Budh Nagar, Uttar Pradesh, India., Gangwani Simran ,   UG MBBS, Noida International Institute of Medical Sciences, Gautam Budh Nagar, Uttar Pradesh, India., Chauhan Vinita ,   UG MBBS, Noida International Institute of Medical Sciences, Gautam Budh Nagar, Uttar Pradesh, India., Mohane Vijay ,   UG MBBS, Noida International Institute of Medical Sciences, Gautam Budh Nagar, Uttar Pradesh, India.
Published: January 2024

Acute aortic dissection is an uncommon disorder which can have fatal results in the event of treatment delay or misdiagnosis. This case examines a 61-year-old woman presenting with hypertension initially diagnosed as hypertensive crises relieved by antihypertensive medication. She was referred to the cardiology with clinical suspicion of acute coronary syndrome (ACS). However, she was later diagnosed with acute aortic dissection by CT-angiography and sent to surgical unit. Aortic dissection patient presents with many non-specific complaints so mostly misdiagnosed. This case report of a 61-years-old female with diagnosis of Stanford Type A acute aortic dissection misdiagnosed as a hypertensive crisis aiming towards highlighting this potentially fatal condition and importance of early diagnosis The early assessment and early CT-angiography can help in reaching the diagnosis so that early and accurate intervention can be done to save the life of patient from this fatal disease.
AN EXPERIMENTAL STUDY TO ASSESS THE EFFECTIVENESS OF ART THERAPY UPON STRESS AMONG PREGNANT WOMEN IN A SELECTED COMMUNITY, BENGALURU KARNATAKA BY THE STUDENT OF SMT.NAGARATHNAMMA COLLEGE OF NURSING
Authors:   Principal and Professor Dept of Medical Surgical Nursing., Nanjappan Devi , Dennis Dency ,   H.O.D & Guide Dept. of Mental Health Nursing., Saha Anushree ,   BSC Final Year Students., Bawlia Ankita ,   BSC Final Year Students., Mallick Anushree ,   BSC Final Year Students., Mondal Ankita ,   BSC Final Year Students., Paul Ankita ,   BSC Final Year Students.
Published: January 2024

Background: Pregnancy is defined as the period from conception to birth. After the egg is fertilized by a sperm and then implanted in the lining of the uterus, it develops into the placenta and embryo and later into foetus. Pregnancy usually lasts for 40 weeks, beginning from the 1st day of the womens last menstrual period and lasting for 3 months. The changes observed in the system from conception to pregnancy, are principally the following namely- amenorrhoea, morning sickness, fatigue, heart burn, increased salivary discharge, occasionally depravity of appetite , headache, irritability of temper, the pressure of increasing pregnancy, protrusion of umbilicus, sometimes, varicose, swellings of the lower extremities, the breast also enlarge, an areola or brown circle is observed around the nipples and a secretion of lymph, composed of milk and water takes place. Stress is a natural human response that prompts us to address challenges and threats in our lives. It usually happens when a person is in a situation that he or she do not feel like they can manage or control. Stress in pregnancy may lead to higher blood pressure. This puts the pregnant women at risk of serious increased blood pressure, called pre-eclampsia, preterm birth and having a low birth weight infant. Method: This chapter deals with the description of research methodology. It is most important in research as it is the framework in conducting study. It indicates general pattern for organizing the procedure together valid and reliable data for investigations. It includes research designs, population and sample, sampling technique, inclusion and exclusion criteria, instruments, data collection and methods of data collection procedure and data analysis plan. Results :Through this study we came to the conclusion that the maximum samples or the pregnant women had somewhat recovered from their increasing level of stress by the interventions of art therapy that was provided to them for fifteen days and also the mean value of the pretest and the post test score is 20.01 and 14.4, respectively.
A STUDY TO ASSESS THE EFFECTIVENESS OF VIDEO ASSISTED TEACHING (VAT) ON PREVENTION OF HYPERTHYROIDISM AND ITSASSOCIATED FACTORS AMONG THE STUDENTS OF SECOND YEAR GNM AT A SELECTED SCHOOL OF NURSING, BENGALURU, KARNATAKA, BY THE STUDENTS OF SMT. NAGARATHNAMMA COLLEGE OF NURSING
Authors:   Professor and Principal of Smt Nagarathnamma College of Nursing., Nanjappan Devi , Snehalatha Reddy P. ,   Guide & H.O.D of Medical Surgical Nursing., Parvej Tanisa ,   Co-Authors, Final Year Studends., Ghosh Swagata ,   Co-Authors, Final Year Studends., Yangzom Tsering ,   Co-Authors, Final Year Studends., Tamang Sushmita ,   Co-Authors, Final Year Studends., Das Tanmoy ,   Co-Authors, Final Year Studends., Ahammed Tousik ,   Co-Authors, Final Year Studends.
Published: January 2024

Background: HEALTH IS NOT VALUED TILL SICKNESS COMES. Hyperthyroidism occurs when the thyroid gland makes too much of thyroid hormone. This condition also is called objective thyroid.Hypothyroidism speeds up the bodys metabolism. It causes many symptoms such as a weight loss, hand tremors and rapid or irregular heartbeat. A 2018 study explain that genetic factors can make many thyroidissues including hyperthyroidism. There is good scientific evidence that hyperthyroidism has important genetic component in many cases because an individual has a mutation in one and more genes. These mutations alter typically thyroid function, causing it to procedure to much T4 and T3. It is not exactly Clear why these genetic mutation as Ise.A 2021 study lists some genes that may play a role in hyperthyroidism. These include: -HCA, CTLA4, FCRL3, RNASET2, TSHR. Study notes that genetic factors might account 79% of an individual predisposition to develop gravis disease. Prevalence of hyperthyroidism is 0.8% in Europe and 1.3% in USA. Hyperthyroidism has been also studied in Cochin, India, subclinical and over hyperthyroidism were present in 1.6% and 1.3% of subject participating in community survey. Hyperthyroidism increases with age and is more frequent in women. The prevalence of hyperthyroidism seems slightly more frequent in white people than in other rules. The medicine of mild hyperthyroidism is also reported to be binges in iodine - deficient areas than in iodine sufficient areas. Hyperthyroidism is very common disease condition nowadays, so we have chosen our sample as second year GNM because, as they are already studying it so to assess their knowledge and to provide more knowledge about hyperthyroidism to give proper information and treatment about hyperthyroidism. Prevention can be done by getting your hormone levels checked all through pregnancy and 6 months after giving birth, keeping diabetes under control, check your vitamin B12 levels. People with previous anemia are at high risk, check for thyroid levels regularly if your family history has it.
EFFECT OF SWEDISH MASSAGE AND HOT MUD WITH CALOTROPIS GIGANTEA APPLICATION AMONG KNEE JOINT OSTEOARTHRITIS CASES-A RANDOMIZED CONTROL TRIAL
Authors:   Professor Cum Chief Medical Officer, Nandha Naturopathy and Yoga Medical College and Hospital, Erode, Tamilnadu., Mohanan Renjish , Subha M. Jerin ,   Professor Cum Senior Medical Officer, Nandha Naturopathy and Yoga Medical College and Hospital, Erode, Tamilnadu., B.A. Jhivyaa ,   Assistant ProfessorCum Medical Officer, Nandha Naturopathy and Yoga Medical College and Hospital, Erode, Tamilnadu.
Published: January 2024

Osteoarthritis of the knee joint is a most common type of degenerative joint disease-causing substantial pain and disability globally. Despite affecting over 20 million individuals in the United States and an anticipated 100 million worldwide by 2030, the molecular mechanisms of KOA initiation and progression remain inadequately understood, with no available interventions to restore degraded cartilage or impede disease advancement. Current treatments, including medications and surgical interventions, exhibit limited efficacy and potential side effects. This study aimed to investigate the effectiveness of a combined treatment comprising Swedish massage, hot mud, and Calotropis gigantea application in reducing pain, disability, and joint stiffness in individuals with KOA. Eighty participants (35 males, 45 females) aged 40 to 75 years with clinical knee osteoarthritis were randomly assigned to either a Study group (Swedish massage with Hot Mud and Calotropis Gigantea leaves) or a Control group (Swedish massage with Hot Mud). Pain intensity was measured using a visual analogue scale (VAS), and the Western Ontario and McMaster Universities Secondary Osteoarthritis index (WOMAC) assessed pain, disability, and joint stiffness. The intervention was applied daily for 10 days, and pre- and post-intervention comparisons were analyzed. Both groups exhibited a significant reduction in pain, disability, and joint stiffness. However, the Study group demonstrated a greater reduction than the Control group, with statistically significant differences in VAS and WOMAC scores. No adverse events were reported. Calotropis gigantea, known for its anti-inflammatory properties, combined with Swedish massage and hot mud, showed a potential synergistic effect. Swedish massage enhances blood circulation and muscle relaxation, while hot mud provides heat therapy. The combination may improve the penetration of therapeutic agents, leading to more profound effects. The study suggests that the combined treatment holds promise for addressing knee-related issues. The combined treatment involving Calotropis gigantea application, Swedish massage, and hot mud demonstrated a significant reduction in knee pain, disability, and joint stiffness. The potential synergistic effect of these interventions warrants further investigation to validate their therapeutic benefits, emphasizing the need for caution and additional research to ensure safety and efficacy.
SOCIO- DEMOGRAPHIC PROFILE AND COST INCURRED BY THE PATIENTS ADMITTED UNDER AB-NHPM SCHEME AT A TERTIARY CARE HOSPITAL
Authors:   Senior ResidentDepartment of HospitalAdministration,SKIMS., Iqbal Anam , A. Jan Farooq ,   Professor Department of HospitalAdministration, and Medical Superintendent,SKIMS., Khalil Ifrah ,   Senior ResidentDepartment of HospitalAdministration,SKIMS., Illahi Khan Ammar ,   Diploma Gynae-Obstretics, Infertility Specialist.
Published: January 2024

Investmentinhealthcareisanecessarysocialinvestment. Ayushman Bharat Yojana- National Health Protection Scheme (AB-NHPM) inSeptember 2018 that was rolled out across all states/UTs in all districts of thecountry. The aim of this programme was to provide a service to create a healthyandcontentnewIndia. Objectives:To determine the socio demographic profile of patients admitted under AB-NHPM and the cost incurred by these patients during a study period of one year from November 2019 to November 2020. Methodology:Retrospectiveandprospectiveobservationalrecordstudywasconductedonpatients admitted under Ayushman Bharat category. Results:Out of 1900 retrospective patients studied and 1433 prospective group of patients majorly people belonging to lower income groups,elderly and those belonging to rural areas availed the benefit. Conclusion: Lot has been done and further more needs to be done to extend this scheme to cater to a wider range of ailments.
TO ASSESS EFFECTS OF PNEUMOPERITONEUM ON VENTILATORY MECHANICS AND HEMODYNAMICS DURING LAPAROSCOPIC CHOLECYSTECTOMY IN OBESE AND NON-OBESE PATIENTS
Authors: Nath Omkar , Malik Neha , Singh Sukhvir , Batra Y.K
Published: January 2024

Aim: The aim of the study was to assess effects of pneumoperitoneum on ventilatory mechanics and hemodynamic during laparoscopic cholecystectomy in obese and non-obese patients Method: A total of 100 patients were divided into two groups of 50 each. Obese (O) group consisted of 50 patients with BMI>30 kg/m2 and non-obese (NO) group consisted of 50 patients with BMI<30 kg/m2. Anaesthesia protocol was kept uniform in both the groups. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), peripheral oxygen saturation (SpO2), end-tidal carbon dioxide (EtCO2), perfusion index (PI), peak (PPEAK), plateau (PPLAT) and driving (PDRIVING) pressures, static (CST) and dynamic (CDYN) lung compliances were measured at baseline and at sequential time intervals following induction of anaesthesia, insufflation, desufflation and before extubation. Results: On induction of anaesthesia, a decrease in HR was observed in non-obese patients whereas an increase was observed in obese patients though statistically non-significant (p>0.05). A higher SBP, DBP and MAP was observed following insufflation, after desufflation and before extubation in the obese patients but was non-significant . The PI value was high in obese patients though non-significant. Also, EtCO2 values remained minimally elevated in obese patients but were statistically insignificant. PPEAK, PPLAT as well as PDRIVING remained high in obese individuals following insufflation, after desufflation, and before extubation and were significant (p<0.05). CST and CDYN remained low in obese patients following insufflation, after desufflation, and before extubation and were statistically significant (p<0.05). Conclusion: Obese patients undergoing LC have slightly higher hemodynamic variations than non-obese patients, but non-significant (p>0.05). The respiratory parameters PPEAK, PPLAT and PDRIVING remained elevated whereas CST and CDYN remained low following insufflation, after desufflation, and before extubation in obese patients as compared to non-obese patients and were statistically significant (p<0.05).
CARACTERISATION DE LA SAISON DES PLUIES (DE 1950 A 2013) DANS UN CONTEXTE DE CHANGEMENT CLIMATIQUE : CAS DU SENEGAL ORIENTAL
Authors:   Laboratoire de ClimatologieetdEnvironnement (LCE) - Departement de Geographie, UniversiteCheikh Anta DIOP de Dakar- Senegal., Faye Mbagnick , Tine Dome ,   Laboratoire de TeledetectionAppliquee (LTA) - Institut des Sciences de la Terre (IST), UniversiteCheikh Anta DIOP de Dakar- Senegal., Sarr Ibra ,   Laboratoire de ClimatologieetdEnvironnement (LCE) - Departement de Geographie, UniversiteCheikh Anta DIOP de Dakar- Senegal.
Published: January 2024

Les dates de demarrage et de fin de la saison des pluies ont une importance capitale pour les differentes varietes cultivees dans les pays saheliens dune maniere generale et au Senegal en particulier. En effet, les debuts et fins des hivernages permettent de connaitre la duree de lhivernage ainsi que les mois les plus pluvieux. Sa connaissance se revele ainsi indispensable afin de mieux accommoder le cycle vegetatif des varietes cultivees a la duree de la saison pluvieuse. Cest dans ce cadre que la presente etude est initiee pour analyser les caracteristiques de la saison des pluies dans la partie orientale du Senegal qui est lune des plus importantes zones de cultures commerciale et vivriere du Senegal. La demarche methodologique adoptee combine lanalyse statistique de donnees pluviometriques (journaliere et mensuelle) et des enquÃªtes de terrain. Lanalyse de la pluviometrie, basee sur les donnees des stations de Bakel (domaine sud sahelien), de Tambacounda (domaine nord soudanien) et de Kedougou (domaine sud soudanien), revele que lhivernage commence normalement a Tambacounda en juin et se termine en octobre avec le mois daoÃ»t comme le plus pluvieux.
OVARIAN SERTOLI-LEYDIG TUMOR: CLINICAL AND ANATOMO-PATHOLOGICAL ASPECTS, ABOUT AN OBSERVATION
Authors:   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Traore I. , Taghzouti H ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Idrissi M. B. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Saoud K. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Mamouni N. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Errarhay S. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Bouchikhi C. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES., Banani A. ,   Service de Gynecologie Obstetrique I CHU Hassan II, Faculte de Medecine, de Pharmacie et de Medecine Dentaire, Universite Sidi Mohammed Ben Abdellah, FES.
Published: January 2024

Sertoli Leidig tumors are rare tumors, representing less than 0.5% of ovarian tumors. It is the moderately and poorly differentiated forms which are the most common. We report a case in a 25-year-old female patient with right ovarian localization. The patient underwent right adnexectomy surgery which removed the tumor. The management of these tumors is not good, it is a tumor with a relatively good prognosis due to early diagnosis with a lesion still limited to the ovary.
THE IMPACT OF CANALS REHABILITATION AND CONTINUOUS FLOW SYSTEM ON APPLICATION OF MODERN IRRIGATION SYSTEMS IN EGYPT
Authors:   Water Management Research Institute, National Water Research Center, P.O. Box 13621/5, Delta Barrage, Cairo, Egypt., Salah Mohamed Magda , Kamal Soussa Hoda ,   Department of Hydraulics and Irrigation, Faculty of Engineering, Ain Shams University, Egypt., Ali Ali Hassan Nagy ,   Department of Hydraulics and Irrigation, Faculty of Engineering, Ain Shams University, Egypt., Tahir El Gamal Talaat ,   Water Management Research Institute, National Water Research Center, P.O. Box 13621/5, Delta Barrage, Cairo, Egypt.
Published: January 2024

With The intent of Ministry of Water Resource and Irrigation in Egypt to apply the modern irrigation system in the old land, it is important to understand the impact of canals rehabilitation and water distribution system on such application. The study investigated such impact through studying two canals, the first canal (Branch # 11) in West Delta, and the second canal (Dakalt canal) in Middle Delta. The study discussed the accurate application of the continuous flow based on the experiences of the developed countries, and it used the simulation model (HEC-RAS) to test the ability of both canals to convey the required water under different water abstraction scenarios. These scenarios were irrigating throughout the whole time, through the whole days of Onperiods. Both systems worked properly for the first two scenarios, while there was aproblem in the third scenario. The discussion highlighted that accurate application of the continuous flow requires enhancing the performance of the irrigation network, besides precise calculation of water requirements. The study conduct that adapting water distribution system before applying modern irrigation system is essential to avoid the failure of such application.
INTEGRATING ACUPRESSUE TECHNIQUE WITH NURSING CARE
Authors:   Assistant Professor ACON Amity University Haryana., Richard Qadir Harshna
Published: January 2024

Based on traditional Chinese medicine principles, the practice of utilizing acupressure to relieve symptomslike pain, during first stage of labor, diverse pain, nausea vomiting, discomfort, sleep quality, fatigue, dysmenorrheaetc., aid in healing process, induce relaxation, and enhance overall well-being1.Acupressure serves as a complementary therapy employing fingers and hands to stimulate acupoints and maintain the balance of energy. A review study explored that Acupressure demonstrates efficacy in alleviating diverse types of pain across various demographics. This review initiates the establishment of a robust evidence foundation supporting acupressures role in pain management. Healthcare providers could consider integrating acupressure into their practice as a viable alternative therapy to assist patients experiencing pain2.This noninvasive technique has been demonstrated to be successful, has no risk, and is simple to incorporate into nursing practice/ nursing care1.According to some preliminary research acupressure may be beneficial for headache, post operative pain, and low back discomfort. Pain from further illness might also help. The LI 4 pressure point is occasionally used to treat headaches3. As part of their emphasis on providing holistic patient care, nurses are increasingly using acupressure to help comfort, pain management and symptom control. According to many research reports, acupressure may be regarded as a viable nursing intervention4. The author explores potential clinical applications of acupressure, delineates the technique, discusses methods for evaluating patient outcomes and proposes strategies to enhance future research on this integrative intervention.
Reading Gokturkish text with the Yolo object detection algorithm
Authors: Karakaya Mevlut , Ersoy Sadberk , Feyzioğlu Ahmet , Ersoy Sezgin
Published: January 2024

This study has important scientific, cultural and economic contributions. From a scientific point of view, the decipherment of Gokturkish texts is of critical importance for research on Turkish culture, history and language. This study will enable historians and researchers to analyze these documents more quickly and effectively. Culturally, the reading of Gokturkish texts will help us gain a deeper understanding of Turkish culture and history. For linguists and cultural researchers, understanding these texts can offer new perspectives on the richness and cultural heritage of the past. From an economic point of view, this thesis argues that computer-assisted reading technology can contribute to a faster and more efficient reading and understanding of Gokturkish texts, making it easier to analyze the documents. This in turn frees up more time and resources for researchers and cultural experts, allowing them to focus on future work.
Urban morphology and housing stock granularity: a cross-scalar analysis
Authors: Kayatekin Cem , Uribe Lorenzo
Published: January 2024

Do urban-morphological parameters trickle down to impact the diversity and granularity of a district’s housing stock? Do urban-morphological parameters impact housing rental values? These are the main questions underpinning this mixed-method study of four districts across Madrid and Barcelona—two districts developed in a bottom-up manner and exhibiting high morphological heterogeneity, and two developed in a top-down manner and exhibiting high morphological homogeneity. The large-scale statistical analyses conducted via the course of this research delves into the cross-district variations and commonalities of residential values, dwelling unit sizes, plot sizes, block sizes, and street widths. Three findings of import are uncovered—(1) possessing an intricate urban-morphological (or housing stock) granularity does not come hand-in-hand with having high urban morphological (or housing stock) diversity; (2) despite not possessing a higher diversity of urban morphological elements, the bottom-up districts still behaved as slightly-divergent and more-affordable real estate bubbles when compared to the top-down neighborhoods; and (3) across all the districts examined, smaller-scale plots consistently supported more than their expected share of smaller-scale dwelling units.