bluuebunny/crossref_metadata_2025 huggingface dataset:
INVESTIGATION OF THE EFFECT OF THE DISCONTINUITY DIRECTION ON FLUID FLOW IN POROUS ROCK MASSES ON A LARGE-SCALE USING HYBRID FVM-DFN AND STREAMLINE SIMULATION
Authors: Namdari Sajad , Baghbanan Alireza , Hashemolhosseini Hamid
Published: September 2021

Understanding the fluid behaviour in rock masses is of great importance in various rock mass-related engineering projects, such as seepage in tunnels, geothermal reservoirs, and hazardous waste disposal. Different approaches have been implemented to study the flow pattern in fractured porous rock masses. Laboratory experiments can provide good information regarding this issue, but high expenses aside, they are time-consuming and suffer the lack of ability to study field scale mediums. Numerical methods are beneficial in simulating such mediums with the Discrete Fracture Network (DFN) method in terms of costs and time as they offer sufficient flexibility and creativity. In this paper, a Matlab code was extended to study the flow regime in a Dual Permeability Media (DPM) with two point sources in the right and left side of the model as an injector and a producer well, respectively. A high permeability discontinuity with different angles was embedded in a very low-permeability limestone matrix. Pressure equations were solved implicitly with a two-point flux approximation scheme of the Finite Volume Method (FVM). Streamlines were traced in the medium and used to analyse the model’s hydraulic behaviour with the aid of Time Of Flight (TOF) for each point. The results show that the FVM-DFN hybrid method can be used as a fast method for fluid flow in DPM with the aid of streamline simulation to study the fluid flow in a large model with discontinuity.
VARIATION OF THE INTRINSIC ROCK PROPERTIES ON HOEK-BROWN FAILURE CRITERION PARAMETERS
Authors: Salajegheh Sina , Shahriar Kourosh , Jalalifar Hossein , Ahangari Kaveh
Published: September 2021

The Hoek-Brown (H-B) criterion is one of the most commonly used rock failure criteria in recent years. This criterion includes a constant parameter called mi which is a fundamental parameter for estimating rock strength. Due to the importance of the mi parameter in the H-B criterion, it is necessary to conduct comprehensive studies on various aspects of the effect of this parameter on the behavior of rocks. Therefore, in this study, using numerical simulation of the Triaxial Compressive Strength (TCS) tests in PFC-2D code, the effects of microscopic properties of different rocks on the H-B parameter mi have been studied. Based on the results of this study, it was found that the effects of micro-parameters on the H-B parameter mi can be different depending on the type of rock, however this parameter has an inverse relationship to the micro-parameters of bond tensile strength and bond fraction of the rocks. Also, the mi parameter increases with an increase in the micro-parameters of the friction coefficient, the friction angle, the particle contact modulus, and the contact stiffness ratio of rocks.
Persuasion and administrative coercion as methods of public (state) administration
Authors: Popov L. L.
Published: September 2021

The article reveals the essence, purpose and content of these management methods, their objective conditionality by material and superstructure factors, the state structure of society, which can be democratic or totalitarian. It follows from this that not a single state, including the Russian Federation, is free in the choice of methods of managing the affairs of society. The main method of influencing public relations, the interaction of people is persuasion. The slogan of the classic — “We must at all costs first convince, and then compel” — remains unshakable in our days. The article provides specific signs of persuasion and administrative coercion, which make it possible to clearly distinguish them, not to oppose and not to lose, as happened in modern life with persuasion and its most important form — education.
The role of the coercive influence method in improving the legal regulation of administrative coercion measures
Authors: Kaplunov A. I.
Published: September 2021

The legal regulation of administrative coercion measures as the basic structural units of administrative coercion is considered in the article through the prism of the concept of "method of coercive influence", which is the key, essential for the characterization of the content of the administrative coercion measure, and the elements that determine the legality of its application. The chosen methodological approach allowed the author to assess at a deeper theoretical level the quality of the legal regulation of certain administrative enforcement measures used by the police, and to identify the shortcomings associated with the consolidation in the legislation of the method of coercive influence of such coercive measures as the use of physical force and firearms, suspension from driving a vehicle, to identify problematic issues in the use of firearms by police officers, due to the regulation of the grounds, the procedure and conditions for the implementation of this method of coercive influence. A variant of the concept of "resistance" is proposed to eliminate the gap in the current legislation.
Regulatory issues and law enforcement practice of using coercive measures, such as isolation and involuntary hospitalization on epidemiological grounds
Authors: Sokolova O. V.
Published: September 2021

The article examines the possibility of applying compulsory hospitalization and isolation to persons infected with the coronavirus, and to persons who have been in contact with the former. There are two mechanisms of coercion: coercive measures and mandatory measures. A distinction is made between the concepts of hospitalization and isolation, and legal subjects of the relevant legal relations are analyzed. The scientific and theoretical provisions of the article are illustrated by the author using the example of Russian legislation (codes and other federal laws, bylaws of the Ministry of Health of the Russian Federation and Rospotrebnadzor, relating to both substantive law and procedural law), as well as practice that has developed or is only emerging in domestic courts. At the end of the article, the existing regulatory problems, in particular conflicting regulation, are described and some solutions are proposed.
Administrative prevention measures and issues of their administrative procedural application
Authors: Spiridonov P. E.
Published: September 2021

The subject of the study in this paper is administrative prevention measures and their variety, such as preventive measures. The purpose of the study is to analyze the nature of administrative prevention measures and their administrative procedure. The paper concludes that it is premature to talk about the existence of proceedings on the application of administrative prevention (preventive) measures, since the Russian Federation has not fully developed a system of administrative procedural rules governing this type of proceedings from the stage of initiating an administrative case to the stage of appeal. At the same time, taking into account the introduction of a risk- oriented approach in public administration, the need for the formation of this type of administrative proceedings increases. It is also suggested that the peculiarities of the legal regulation of the procedural procedure for the application of administrative prevention measures depend on two important conditions: (1) the effectiveness of the application of the relevant measure by law enforcement officials and their officials; (2) the ability to ensure respect for the rights and freedoms of a person and citizen in the existing procedure of application.
Administrative proceedings in Roman law
Authors: Gridin S. I.
Published: September 2021

The article deals with the issues of administrative proceedings in Roman law. Its beginning was laid in the 5th century BC by the laws of ХII tables. They briefly deal with the issues of legal proceedings, which at that time was called court agreement. Free citizens gathered at the forum (city square), where the plaintiff presented claims to the defendant. In Roman law, the rule was established to make claims through claims, which the magistrate (praetor) had to support. The judges were elected by the people. Gradually, the praetors changed the formulas of claims, which contributed to the development of Roman law. Often they proceeded not from the law, but from the circumstances of the case, therefore they could instruct the judge to consider the case “in good faith.” Gradually, various forms of claims were formed, which contributed to the improvement of administrative proceedings. In Roman law, many concepts were laid that have remained in modern legal proceedings. This is the election and turnover of judges, the necessary defense, the writ of execution and the persons who monitored their execution; jurisdiction; corruption; search procedure; jurisdiction; privilege; appeal against court decisions; requirement for witnesses; consideration of cases by the police; torts; limitation of actions; and some others. This makes the study of Roman justice relevant.
Improving state policy on forest fire prevention and extinguishing: administrative and legal aspects
Authors: Oleynik M. V.
Published: September 2021

In this article, an attempt is made to analyze the existing legal mechanisms for the formation of the state system for the prevention and elimination of forest fires, to outline ways to improve state policy in this area. The author presents the results of the analysis of the content of text arrays of normative legal acts regulating the prevention and elimination of forest fires. disaster Medicine of the Ministry of Defense of the Russian Federation. The genesis of legislative acts reflecting the functions of the state to protect the population and territories from emergency situations is carried out. With the help of content analysis, the characteristics of various governing documents in the field under consideration are given. The main key points contained in the analyzed documents are shown. The positive and negative sides, as well as contradictions affecting the functioning of the RSChS and the functional subsystem of the Federal Forestry Agency for the protection of forests from fires and their protection from pests and forest diseases are revealed. The qualitative approach of content analysis allowed us to determine the content of problematic issues that are poorly reflected in regulatory legal documents, or have a logical contradiction when compared with each other. The proposals for improving the state policy in the field of prevention and elimination of forest fires in Russia are substantiated.
Administrative punishment of legal entities as an administrative coercion measure
Authors: Politova E. Yu.
Published: September 2021

Administrative penalties applied to legal entities are among the most common and effective measures of administrative coercion. The analysis of the legislation made it possible to identify the system of administrative penalties applied to legal entities in the Russian Federation. The author characterizes the system and the main types of administrative penalties of legal entities, such as a warning, an administrative fine, confiscation, administrative suspension of activity. It is noted that the most common is an administrative fine. However, there are problems with its appointment. The materials of judicial practice on the application of administrative sanctions to legal entities are analyzed. As a result of the analysis, the need to optimize administrative penalties applied to legal entities is noted. The article examines the norms of the draft Administrative Code of the Russian Federation in relation to administrative penalties applied to legal entities. The positive and negative aspects of the proposed codification are noted.
Suspension of executive acts in the constituent entities of the Russian Federation as a state coercion measure
Authors: Zaycev D. I.
Published: September 2021

The article contains analysis of one of the least studied public enforcement measures which is suspension of acts of the higher official (the head of the highest executive body of the state power), executive bodies of the Russian Federation constituent entities.The author focuses on the presidential decision to enact the public enforcement measure that is considered in the presented article, in particular, the form of the legal act of governance which implements that presidential decision, the wording of the name and the content of such a legal act is under review. It is shown that neither legislative regulation nor enforcement practice is perfect when it comes to the sphere of federal relations.Furthermore, the presented article addresses such issues as normativity and legal certainty of decrees and orders of the Head of State which implement the presidential decision to suspend the act of the executive body of the Russian Federation constituent entities.The historical and legal part of the subject of study is presented by statistical data that makes some corrections to the usually reported data considering the number of legal presidential acts that were mentioned.
Treatment of acute rheumatism with streptocide
Authors: Sluchevsky I. S.
Published: September 2021

Now, most clinicians consider rheumatism as the result of an allergic reaction of a host to an infection; it is assumed that the macroorganism has an increased sensitivity not only to specific allergens, but also to nonspecific, so-called paralergens. The bacterial factor here is most often streptococcus.
Permeability of the blood-brain barrier for sodium iodide in some organic diseases of the nervous system
Authors: Popov N. I.
Published: September 2021

In the physiology and pathology of the nervous system, much attention is paid to the issue of the permeability of the blood-brain barrier. Along with the theoretical interest, this question is important for the practicing physician. If, on the one hand, a violation of the barrier leads to a disease of the nervous system, then, on the other hand, in diseases of the nervous system, it is often necessary to force the permeability of the barrier in one way or another in order to enable various medicinal substances (arsenic, mercury) to enter the cerebrospinal fluid
Schwarzman's phenomenon caused by concomitant flora in tuberculosis animals
Authors: Bukh F. L.
Published: September 2021

The presence of concomitant bacterial flora in the deep parts of the lung tissue, in pneumonic foci, and sometimes in the blood in chronic pulmonary tuberculosis can be considered proven, but this is not yet proof of the participation of this microflora in the pathogenesis of the process. The issue remains controversial, despite its many-sided study.
On the issue of growing a gonococcus on media without ascitic fluid
Authors: Kuryanova E M.
Published: September 2021

The classical method of cultivating a gonococcus on nutrient media with the addition of ascitic fluid presents a number of inconveniences in obtaining cultures in large quantities in the production of vaccines. From the literature on this issue we know a number of proposed nutrient media in which the ascitic fluid is replaced by other, protein-containing substances.
The first Soviet tomograph.
Authors: Novikov V. A.
Published: September 2021

Modern X-ray diagnostics using transillumination and an image still has drawbacks, since when examining the internal organs, especially the chest, the layering of ribs and muscles on the insides is a big hindrance.
Case of kyphosis after tetanus
Authors: Voskresensky G. P.
Published: September 2021

In 1917, Meyer-Weiler first described a case of kyphotic curvature of the spine after tetanus. This was followed by a description of similar cases by other authors.
On injuries to the skull in a state of intoxication
Authors: Fadeev I. P.
Published: September 2021

Prof. Ignatovsky points out that the symptoms of arousal and depression under pressure on the brain are somewhat reminiscent of alcohol poisoning, which is why it is not surprising that there have been cases when the symptoms caused by excessive intoxication were mistaken for signs of pressure on the brain, but even more often there are reverse errors: pressure on the brain taken for drunkenness.
Castrovilli. Treatment of malarial hemoglobinuria with C-vitamin acid. (Minerva Medica. Turin. V I. 18 / III 1937)
Authors: Dembskaya V.
Published: September 2021

The author obtained good results from the daily injection of 0.1 C-vitamin acid in one case of nephrohemolytic hemoglobinuria in tertian malaria.
Bernhardt, F. Acute diseases of the pancreas after biliary tract surgery. (Bruns Beitröge zur klin. Chirurgie. Bd. 165. H. 4.1937. July, pp. 512-523)
Authors: Mayat V.
Published: September 2021

Acute pancreatic necrosis can occur several months or even years after biliary tract surgery. This complication can be assumed if a patient who has undergone surgery on the biliary tract suddenly falls ill with acute pain in the upper abdomen.
About malaria
Authors: Mühlens’a Р.
Published: September 2021

During the work of the German Medical Mission in Russia, we could be convinced that issues related to malaria are of particular interest among our Russian comrades.
A few words about surgical treatment of large rectal prolapse
Authors: Vishnevsky A. V.
Published: September 2021

To date, there is no noticeable certainty in the question of the surgical treatment of rectal prolapse. The abundance of treatments is clear evidence that a reliable method is still available. not yet available.
Spontaneous healing of malignant neoplasms. Saue g bru.ch (Deut. Med. Woch., 1922, no. 5)
Authors: G. V.
Published: September 2021

Saue g bru.ch (Deut. Med. Woch., 1922, No. 5) observed 3 cases of complete spontaneous healing of neoplasms, the certainty of the malignant nature of which was precisely established. another, in a woman of 56 years, - advanced breast cancer, in a third, in a 22-year-old girl, - spindle cell sarcoma of the hip. The author also cites a number of similar cases from the literature. Such cases, apparently, speak for the possibility of conservative treatment of malignant neoplasms with such means as x-rays, Proteinkrpertherapie, etc.
On the X-ray technique of malignant tumors Brock (S’trahlentherapie. Bd. 13, № 1)
Authors: G. V.
Published: September 2021

Analyzing this technique Brock (S'trahlentherapie. Bd. 13, No. 1) strongly points out the need for the corresponding lymph glands to be protected from the action of x-rays during the X-ray examination of malignant tumors.
Organotherapy of diabetes mellitus.
Authors: G. V.
Published: September 2021

According to the observations of Loe-nіnga, in the treatment of diabetes mellitus, in addition to the appropriate diet. it is necessary to strive to eliminate those disorders that depend on the insufficiency of the internal secretion of the pancreas.
Etiology of eclampsia. Schönfeld (Arch. F. Gyn., Bd. 115)
Authors: G. V.
Published: September 2021

Schnfeld (Arch. F. Gyn., Bd. 115) assumes that in the blood of pregnant women there are substances originating from the placenta, namely, enzymes, aminobodies and lipoids, and lipoids are especially pronounced in eclampsia.
Diagnosis and therapy of tubal pregnancy Löhnberg (Zeit. f. Geb., Bd. 84)
Authors: G. V.
Published: September 2021

Based on the analysis of 152 operated cases of tubal pregnancies, Lhnberg (Zeit. F. Geb., Bd. 84) determines the likelihood of sweeping tubal pregnancies with inflammatory diseases of the appendages in 10% and attaches particular importance in recognition to anamnestic indications of cramping pains. Uterine pregnancy after ectopic pregnancy occurs 6 times more often than pregnancy in another tube.
The reason for the closure of the Votall's duct in newborns. Vogt (Fortschr. D. Röntgenstr., 28)
Authors: G. V.
Published: September 2021

Vogt (Fortschr. D. Rntgenstr., 28) made a number of studies with the infection of the circulatory system in newborns through the umbilical vein. For injection he was served with a mixture of 60.0 red lead, 100.0 water, 20.0 chalk and 20.0 gelatin.
Puncture of sinus longitudinalis in newborns. Gordon (Joiirn; of Аш. Med. Ass., 1921, 22)
Authors: G. V.
Published: September 2021

Based on observations of 231 newborns, Gordon (Joiirn; of Ash. Med. Ass., 1921, 22) considers such a puncture to be completely safe.
Migraine treatment. According to the observations of Bgown’a (Journ. Of Am. Med. Ass., 1891, No. 18)
Authors: G. V.
Published: September 2021

According to the observations of Browna (Journ. Of Am. Med. Ass., 1891, No. 18) migraine is often the result of improper diet, namely, an excess of food or carbohydrates, or animal proteins.
Treatment of dorsal tabes with salvarsan and latent lues "a. Pulay (Deut. med. Woch., 1922, Ж 7)
Authors: G. V.
Published: September 2021

With the usual treatment of dorsal tabes with salvarsan, patients often experience strong reactionary phenomena, namely, stomach crises and severe pain, and with the same treatment of latent syphilis, easy fatigue, headaches, weight loss, etc.
Lupus contagion, Burchardi (Deut. Med. Woch., 1922, no. 6)
Authors: G. V.
Published: September 2021

Burchardi (Deut. Med. Woch., 1922, No. 6) found that inoculation of guinea pigs with crusts and pus from lupus ulcers of the skin and nasal mucosa does not cause tuberculosis in animals, while inoculation of tissues.
Blood for major diseases. Brückner (I Vers. d. Opht. Gesel., Heidelberg, 1918)
Authors: Roshchin V.
Published: September 2021

Having studied the composition of blood in 90 patients with eye diseases. - blenorrhoid conjunctivitis, serpiginous ulcer, perforating lesions, sympathetic inflammation and trachoma, Brckner (I Vers. D. Opht. Gesel., Heidelberg, 1918) found that an acute local process in the eye can affect the composition of the blood, and the latter changes depending on the improvement or deterioration of the process.
Mieloma inside the eye. Slock (Klin. Mon. f. Augenheil., 1918)
Authors: Adamyuk V.
Published: September 2021

Slock (Klin. Mon. f. Augenheil., 1918) observed a case of intraocular myeloma. The tumor, occupying a significant part of the vitreous body, sat on the nipple of the optic nerve, being fused also with the membranes of the fundus of the eye and with the sclera around it. The choroid contained deposits of bone tissue, which was in direct contact with the tumor.
Preparing medical sites for the Bolshevik sowing
Authors: Laptev N. A.
Published: September 2021

The socialist reconstruction of agriculture radically changes the face of the countryside from year to year. The collectivization of agriculture and the organization of grain and livestock farms create new forms of labor.
Renal fluid excretion in some groups of female tobacco workers before and after work
Authors: Shulutko I. V.
Published: September 2021

Occupational physiology and occupational pathology are increasingly beginning to address issues related to the functional state of a particular organ in workers of various professions.
To the clinic for undulating fever
Authors: Khnyunin I. D.
Published: September 2021

Under the name of the undulating fever (Febris undulans), a kind of disease is described, characterized by prolonged fever lasting for several months and even, in some cases, more than a year, and the febrile periods are followed by periods of complete or relative apyrexia.
On the question of foreign bodies in the bladder
Authors: Medvedovsky S. Z.
Published: September 2021

Foreign bodies in the bladder are found in both men and women, more often in the latter. They penetrate in two ways: 1st through the urethra, 1st through the bladder wall (gunshot wound to the bladder, surgical interventions on the bladder and on adjacent organs, followed by the penetration of a foreign body into the bladder). Leaving aside the question of the penetration of a foreign body through the wall of the bladder, I will focus on the possibility of penetration of foreign bodies through the urethra.
On the issue of birth injuries of the urinary tract of a woman
Authors: Nikolaev A. P.
Published: September 2021

With minor exceptions, urinary incontinence after childbirth has a traumatic origin. It can be the result of two different reasons, namely, the result of a long standing of the fetal head in the cavity or, more often, in the entrance of the small pelvis and the associated prolonged pressing of the underlying tissues, of which the anterior wall of the vagina with the posterior wall of the bladder and the urethra suffers or re as a result of surgical interventions undertaken for the purpose of delivery without the necessary conditions, more often with an empty bladder and with an unprepared birth canal.
On the relationship of diseases of the eye and lacrimal ducts with the pathology of the nose and its accessory cavities
Authors: Kryindel I.
Published: September 2021

Since the nasal cavity with the paranasal cavities is anatomically and topographically closely connected with the cavity of the orbit, the optic nerve and the lacrimal ducts, it is quite clear that certain pathological processes, both in the nasal cavity and in its sinuses, very often cause diseases eyes, sometimes very serious.
Eye damage due to dental disease
Authors: Blitstein L. B.
Published: September 2021

Recently, a lot of space has been given in the literature to the question of oral sepsis; the possibility of disease of any organ and in particular the eye in the presence of an infectious focus of dental origin is considered established by experimental work and clinical observations.
Catropin therapy of initial states of epidemic encephalitis
Authors: Balaban N. I.
Published: September 2021

Chronic encephalitis, until recently, had no therapy that would give significant and lasting success. The current subject of discussion is the therapy with large doses of atropine, first tried in the Remerovsky sanatorium in Hirsau. Those conducting it speak of an improvement that can be considered practical healing (Roemer).
О. Kauders (Wien. med. Woch., № 37,1931)
Authors: Galant Yves.
Published: September 2021

(Wien. Med. Woch., No. 37.1931), like Shtransky, draws the attention of practitioners to the psyche of patients, recommending them to use psychotherapy in their daily practice. K indicates that doctors have always previously, regardless of the specialty, acted on patients, among other things, psychotherapeutic.
Lange and Schneider (Wilhelm Lange und Kurt Schneider, Ergebnisse der Röntgenbestrahlung bei chronischer Encephalitis epidemica. Psych.-Neurolog. Wschrift No. 1. 1932)
Authors: Galand Yves.
Published: September 2021

(Wilhelm Lange und Kurt Schneider, Ergebnisse der Rntgenbestrahlung bei chronischer Encephalitis epidemica. Psych.-Neurolog. Wschrift No. 1. 1932) report the treatment of ep. encephalitis by X-rays. This treatment was recommended by Economo, used by Nuvol and (Nuvoli) for acute epidemic encephalitis.
Sarbo (Wiener Woch., No. 29, 1931)
Authors: Galant Yves.
Published: September 2021

(Wiener Woch., No. 29, 1931) reports on the treatment of multiple sclerosis with an intravenous vaccine. 12-15 injections make up the course of treatment. The treatment of multiple sclerosis with the vaccine was first used in London, where miss Chevassut discovered a supposedly specific multiple sclerosis virus in liquor patients (live virus in the form of spherical bodies, spherulae).
Clinico-rheoencephalographic correlations in deaf children
Authors: Sitdikov F. G. , Mugerman В. I. , Zotova F. R.
Published: September 2021

The reasons of hearing disorder in children are studied. The neurologic and rheoencephalographic examination of 37 girls from the Medical and Pedagogical Center for children with hearing pathology aged 1011 is performed. The signs of unheavy lesion of the cervical part of vertebral column and brain are revealed in 18 children. The signs of circulatory insufficiency in vertebrobasilar basin are revealed on rheoencephalograms in these children. It is proposed that the reason of deafness in many children is the natal trauma of the cervical part of vertebral column and vertebral arteries.
Peculiarities of the course and outcome of viral hepatitis A in children with acute dysentery Flexner's disease
Authors: Kalyagina L. S. , Manakova E. A. , Krause D. A.
Published: September 2021

The aim of this work was to study the peculiarities of course and outcomes of viral hepatitis A (VHA) in children with acute dysentery Flexner's disease. The results of the study are based on clinical and laboratory examination data of Nizhny Novgorod Children's Hepatitis Center at Infectious Diseases Hospital No. 23 in 1989. 18 children at the age from 3 to 14 years old, who had and had recovered from VGA and acute dysentery Flexner's disease. Mild jaundice form of the disease was found in 2/3 of the children, and moderate - in 1/3 of the children. More than 2/3 of patients were boys of school age.
The protruded pinky finger is a sign of pyramidal insufficiency
Authors: Stankevich E. S.
Published: September 2021

In psychiatry, as it is known, the diagnosis is based mainly on results of conversations and observations of behavior of patients and the course of the disease. During more than 45 years of work as a psychiatrist I have observed many patients with disorders accompanied by pyramidal insufficiency on the basis of cerebral circulatory disorders. When examining them, there was a sign of weakness of adduction of the little finger due to paresis of its adductor muscle - segment C8.
On the problem of secondary prevention of hepatotropic manifestations of dioxyne intoxication
Authors: Khamidova T. V. , Kozhevnikova E. V. , Kiryukhin V. G. , Filatov B. N.
Published: September 2021

The liver morphology in intoxication by 2-(a-fluor-a-trifhiormethoxymethyl) benzimidazol, 2-a- hydrotetrafluorethy) benzimidazol and 5 (6)-(2-oxy-hexafluorisopropil)-2-(a-fluor-a-trifluormethoxymethyl) benzimidazol is studied experimentally on rats. Vaseline oil in large doses manifests hepatoprotector property early in intoxication.
Features of medical and social examination of persons with HIV infection - AIDS when determining disability without specifying the period of re-examination
Authors: Ugleva Elena M. , Karasaeva Lyudmila A. , Yamshchikova T. Yu. , Nurova A. A , Goryainova Marina V. , Paikov A. Yu.
Published: September 2021

Purpose of research. Studying the features of approaches to determining the timing of disability in rehabilitation and expert diagnostics during the examination of persons with HIV infection - AIDS.
Materials and methods. The research materials were the data of Rosstat of Russia, official state statistical reporting: form 7-social security "Information on the medical and social examination of persons aged 18 years and older" for 2019. The data of our own research included the protocols of persons who were examined for HIV infection in the bureau of medical and social expertiseof (MSE) St. Petersburg and other regions: 50 patients examined in the period from 01.01.2019 to 31.12.2020, (observation group) in comparison with the analysis data of 50 protocols of examination of HIV-infected in the period 2017-2018 (control group).
Results and discussion. According to the results of the study, the disability group is determined reliably more often already during the initial examination without a re-examination period (48.64% versus 19%, c2 = 0.491 at the p 0.01 significance level) when carrying out the MSE taking into account the Government Decree No. 339. Establishing disability for patients with HIV-AIDS without a period of re-examination during the initial examination allows them to get out of the supervision of medical and medical-social services.Taking into account that a part of the contingent of patients with HIV-AIDS has a "special mentality" and the presence of psychological and social risks, the lack of systematic monitoring of their treatment and social patronage contributes to an increase in the severity
Changes in cerebral blood flow in formation and initial progressing of cerebrovascular Diseases
Authors: Shestakov V. V.
Published: September 2021

The author investigated 40 patients with initial manifestation of insufficient cerebral circulation and 46 patients with discirculatory encephalopathy. The author showed, that progressing and clinical manifestations of initial stages of cerebrovascular diseases are connected with imperfection of cerebral circulation regulation with phenomena of its depression. In stage of initial manifestation of insufficient cerebral circulation dimyelitic defect prevails in proximal departments of cerebral arteries, and in stage of discirculatory encephalopathy is spreading on parenchymatous vessels.
Vegetovascular disorders in vibration disease and differential therapy using physical factors
Authors: Chudinova О. A. , Obraztsova R. G. , Samokhvalova G. N. , Filatova R. I.
Published: September 2021

Examination and treatment results are given, concerting 205 patients with vibration disease, in the clinical picture of which the most early and most expressed are neurovascular disorders in the system of regional circulation and vegetativesensoric polyneuropathies. It was shown, that in patients with vibration disease lowering of pulse blood supply in distal parts of upper extremities is being observed, as well aS dystoniccondition of arterial bed vessels, whose expression level is correlated with the disease stage. Suggested physiotherapeutic complexes (magnetic therapy, magnetic and laser therapy, aspirin-electrophoresis on the cervical department of vertebral column and hand) favourably enfluence peripheric hemodynamics, thus contributing to regress of basic clinical manifestations of vibration disease.
Prevention system of brain vascular diseases in administrative-managing personnel
Authors: Andreiev A. G.
Published: September 2021

Results of programme usage of pscycoprevention and psycotherapy are given in 1520 people of managing personnel of Nizhney Novgorods large industrial enterprises with different clinical variants of cardiovascular diseases. As a result of implementation of treating complex a positive dynamics of clinical, psycological and neurophysiological indices was shown. It was recommended to implement suggested therapeutic and prevention complexes in insult prevention rooms of medical stations and other out-patient and polyclinic institutions..
Condition of vegetative regulation at concussion of a head brain in children of preschool age
Authors: Seliverstova G. A. , Kalashnicova Т. Р.
Published: September 2021

Peculiarities of infringement of the vegetative status in children, having had concussion of a head brain are revealed. Infringements of vegetative systems activity was displayed by an oppression of eigotrops link, causing unsufficient vegetative reaction and inadequate
Morphological types of constitution in persons with clinical symptoms of lumbar osteochondrosis
Authors: Kadyrovа L. A. , Sak N. N. , Marchenko V. G. , Gelevey O. I. , Nosatov А. V. , Sak А. Е.
Published: September 2021

One of the promising directions in the search for regularities in the course and, consequently, treatment of vertebrogenic diseases of the nervous system (VNS) is an orientation towards integrative principles of diagnosis based on taking into account the constitutional type of a person and constitutionally determined features of his psyche, physiology and body morphology. Constitutional diagnostics is based precisely on these three whales identified by Claudius Galen. The introduction of constitutional diagnostics into the patient examination system immediately introduces a certain order into the medical strategy and tactics.
EFFECTS OF POLYMER CONCENTRATION AND TEMPERATURE ON MICELLIZATION OF CETYLTRIMETHYLAMMNIUM BROMIDE (CTAB) IN AQUEOUS PVP-CTAB MIXED SYSTEM
Authors: MASALCI Özgür
Published: September 2021

Polymeric micelles supply an environment, which can be cautiously regulated for drug delivery. The self-assembly of polymeric micellization is dynamic. Micellization thermodynamic describes how the system defines the formation of micelles. The present study enables the micellization behavior of the surfactants in the presence of polymer to be examined by conductometric and tensiometric methods. The effects of polymer concentration and temperature on the micellization thermodynamics of a neutral soluble polymer and cationic cetyltrimethylammomium bromide (CTAB) surfactant mixture in aqueous medium were investigated. To examine polymer-surfactant interaction, critical micellar concentration (CMC) and thermodynamic parameters such as standard free energy ∆G, enthalpy ∆H and entropy ∆S are calculated by using a pseudo-phase model. Based on CMC, ΔG, ΔH and ΔH, the dependence of the compensation temperature on the polymer effect is discussed. This advanced work to understand micelle stability and compatibility can be comprehensively feasible in polymeric systems.
URBAN TRANSFORMATION PROGRESS OF REINFORCED CONCRETE (RC) AND MASONRY-MIXED BUILDINGS IN ISTANBUL
Authors: AVCI-KARATAŞ Çigdem , ÇATALKAYA Hakan
Published: September 2021

Istanbul city is the center of increasing industrialization in Turkey with proportionally developing problems, such as distorted settlements, and slums, etc. The rapid migration to Istanbul, which is located in the earthquake hazard risk zone, has resulted in a raised population and these structures. Urban regeneration/transformation/planning is expressed as a comprehensive action plan that aims to provide a lasting solution to be economic, physical, social, and environmental conditions of a diverting region to solve the problems in the cities. This paper analyzes the urban transformation process and applications of reinforced concrete (RC) and masonry or mixed masonry-RC buildings in Istanbul within the scope of the urban planning law called “Law on Transformation of Areas at Risk of Natural Disaster” (Law No. 6306 dated 2012). To reach this goal, a total of 400 risky building forms with 150 RC buildings as well as 250 masonry-mixed buildings considered according to Law No. 6306 is compiled and evaluated as risky building data. The general characteristics of the RC and masonry-mixed buildings in Istanbul are determined by a date range of such as 2012–2020. With the results obtained from the paper, significant contributions have been made to the knowledge and technological capabilities at the international/national level.
Effect of storage duration and analyte concentration on measurement of neutral pH clinical chemistry urine analytes
Authors: Debnath Chapal , Savaliya Niral
Published: September 2021

Background: The aim of the study was focused very keenly in measuring the changes in concentration of sodium, potassium and creatinine in urine, stored for 60 days effect of urinary storage duration of clinical chemistry analytes. This study determined whether patient urine samples can be used for day to day urine quality control.Methods: Spot urine samples were collected from left over samples from the admitted patients in various hospital wards. The samples are kept which its pH was unaltered or unspiked and was aliquoted and deep fridged immediately. These aliquots were melted at an incubator temperature of 86 ºC and was analyzed in the analyzer for 60 days and data were collected for checking variations.Results: With the strenous and continious monitoring from the side of the researchers, the researchers had throughly analysed and found that in both the sets almost all of those analysed urine test of pH 5 and analytes remained very much stable for a period of 60 days which could be used for running daily internal quality controls.Conclusions: Patient urine can be used as internal quality control sample for at least 60 days for sodium, potassium and creatinine. During the 60 days period, there is no appreciable degradation of any of the two sets of samples for sodium, potassium and creatinine measurements.
Effect of physiotherapy on single breath count and breath holding time in COVID-19 patients
Authors: Bhandare Sushama A. , Rasal Sayali S. , Sathe Anil M. , Nagpure Vaishnavi R. , Parmar Urvi B. , Iyer Saraswati K.
Published: September 2021

Background: The novel Coronavirus is known to primarily affect the respiratory system and physiotherapy treatment is integral to combat this infection. However, the assessment of pulmonary function poses a difficult challenge considering the risk of spread of infection and sanitisation of the devices used. Single breath count (SBC) and breath holding time (BHT) can be thus adopted as bedside assessment tests for pulmonary function following physiotherapy treatment.Method: In this a retrospective observational study of 51 COVID-19 patients, mean age 51.7±14.56 years, on room air, admitted in the step-down units of a tertiary care hospital. Patients received standard physiotherapy treatment, within safe hemodynamic limits. Pre and post treatment session SBC was recorded in 32 patients and BHT in 19 patients. Three reading were noted and the best of three readings were used for analysis.Results: The paired t test was used to analyse SBC and BHT. Mean pre and post SBC was 18.25±8.96 and 23.31±9.96 respectively with a mean difference of 5.06 and p<0.0001. Mean pre and post BHT were 19.37 and 23.05 seconds respectively with a mean difference of 3.68 and p<0.0001.  Statistically significant difference in the pre and post treatment session SBC and BHT was observed, indicating a positive effect of physiotherapy treatment on pulmonary function.Conclusion: Physiotherapy treatment shows significant improvement in the pulmonary function in COVID-19 patients. SBC and BHT tests can be used as assessment and prognostic tools for pulmonary function in COVID-19 patients.
Role of dorsal onlay buccal mucosal graft urethroplasty for long anterior urethral strictures
Authors: Pogula Vedamurthy Reddy , Galeti Ershad Hussain , Velivela Venkatesh , Kanchi Bhargava Reddy
Published: September 2021

Background: Treatment of the urethral strictures is challenging and with appropriate evaluation preoperatively and surgery planning it is possible to achieve good results. The objective of the study was to evaluate the efficacy of dorsal onlay buccal mucosal graft urethroplasty in treating long anterior urethral strictures.Methods: Between August 2018 to July 2019 a total of 25 patients with anterior urethral stricture were treated with dorsal onlay buccal mucosal graft urethroplasty. Age, etiology of the stricture, stricture length (≤ 7 cm, and > 7 cm), and site of the stricture were assessed as the factors affecting the success rate.Results: The clinical outcome as Success was defined as the patient not needing any form of urethral instrumentation postoperatively. The mean follow-up period was 18 months. Of 25 patients, 22 (92%) were successful and 3 (8%) were a failure. There was no statistically significant difference between the age groups, etiology of the stricture and success rate (p=0.21 and p=0.444). The statistical difference was significant for the site and length of the stricture by means of success (p=0.005 and p=0.025).Conclusions: Our results show stricture length and localization are the most important variables for good success. Because of less failure rate, single-stage dorsal onlay buccal mucosal graft urethroplasty may be offered as an alternative to staged urethroplasty in case of long urethral strictures.
A study of the knowledge, attitude and behavior among patients with psoriasis vulgaris during the COVID-19 lockdown period
Authors: G. Sukanya , Jotwani Richa , D. Manoharan , Srinivasan Shreya
Published: September 2021

Background: Patients with psoriasis may have been directly impacted by the COVID-19 lockdown and this may have had a significant effect on disease severity and treatment compliance. This study aims to investigate the knowledge, attitude and the behavioral practices of patients with psoriasis during the lockdown period.Methods: A self-assessed questionnaire was employed for the purpose of this study and was answered by 100 patients of clinically diagnosed psoriasis.Results: Although several patients were aware of their condition and its implications, a significant number of responders were found to have a faulty treatment compliance due to the COVID-19 lockdown.Conclusions: To our knowledge, this is the first study that evaluates the knowledge, attitude and behaviour during the COVID-19 lockdown period of individuals who have been clinically diagnosed with psoriasis. This study raises the possibility that the sustained psychosocial stress induced by the current pandemic can potentially lead to exacerbations or onset of common inflammatory skin conditions like psoriasis. The overall compliance to dermatologic therapy was slightly poor as there were frequent concerns regarding the safety of visiting a hospital or a doctor as well as possible financial constraints. As per this study, there is an urgent need to convey the right information about managing psoriasis during the COVID-19 pandemic among both the general population and patients alike.
Su Jok therapy by twist and seed method of therapy to reduce the level of fear on COVID-19’s patient: a case series
Authors: Nurjannah Intansari , Novianti Zakiah , Suharto Agus , Sudarmo Muhammad Yasir , Hariyadi Ki
Published: September 2021

Patients with COVID-19 not only experience suffering from physiological symptoms but also psychological dimensions such as fear. Fear is part of life and the threat of self-existence will increase the fear level. Increased levels of fear will influence the process of healing by disturbing the immunity function. This case series reports the results of Su Jok therapy using the twist and seed method of therapy in reducing the level of fear of patients with COVID-19. Twenty cases of respondents with the average level of fear toward COVID-19 of ≥4 were included in this case reports. Fear level was measured by using the fear scale measurement (FSM). Su Jok therapy was conducted by twisting (120 times) and putting fenugreek seed on the joint of the patients’ index finger in Triorigin fixed joint correspondent of fear. Posttest of fear scale was measured after intervention in the intervals 5, 10 and 15 minutes. In all three interval measurements, there were significant improvements in the fear scale before and after Su Jok therapy (p=0.0001, p<0.05).
Compassionate use of convalescent plasma for the management of severe pneumonia in critically ill COVID-19 patients-a single center experience, Kerala, India
Authors: Paul Mobin , C. G. Priyanka , M. P. Sophy , Abraham Latha , Venkitakrishnan Rajesh , Jos Renji , Varghese Jaicob
Published: September 2021

We assessed treatment effectiveness with convalescent plasma in critically ill COVID-19 pneumonia patients and their association with reduction in C reactive protein level as a sensitive inflammatory marker to the ongoing cytokine storm. Retrospective cohort study based on the detailed electronic medical chart review. The primary outcome was a clinical improvement on day 14, defined as the reduction in cytokine storm as demonstrated by a drop in acute phase reactant C reactive protein; de-escalation from the prior mode of oxygen delivery or not on mechanical ventilation in critically ill COVID-19 patients. C reactive protein was measured by using immunoturbidimetry. IgG antibody against spike protein S1 was measured by chemiluminescent immunoassay. Of 14 patients, all had severe COVID-19 pneumonia [category C], and 9 (64%) were mechanically ventilated soon after the admission into the medical intensive care unit. De-escalation of the oxygenation strategy mode was noted in 11 (79%) patients after convalescent plasma infusion. All patients showed a significant drop in C reactive protein when compared to pre-infusion and post-infusion day 5.  Early compassionate use of convalescent plasma with higher titters of IgG antibodies against S1may positively benefit the overall outcome in critically ill COVID-19 patients with severe pneumonia.