bluuebunny/crossref_metadata_2025 huggingface dataset:
Computer Simulation to Optimize the VFA Alpha Prototype with a Hydraulic Piston Compressor and an Integrated Booster
Authors: Mezulis A. , Safronov A. , Guzeyeva J. , Begens J.
Published: October 2020

Natural gas, including biomethane, is a sustainable alternative fuel. Widening compressed natural gas applications by now is restricted by weakly developed infrastructure. Hygen Ltd. works on “hydraulic piston” technology for natural gas and biomethane compressing, storing, delivering and discharging the storage cylinders by means of an innovative hydraulic boosting technology. Designing of the Vehicle Fuelling Appliance (VFA) demands to take into account thermodynamics and gas dynamics properties at fluid compression and motion. The present paper deals with theoretical characteristics and their link to test measurements regarding a particular VFA HYGEN+ Alpha prototype manufactured by Hygen Ltd.
Characteristics of Staphylococcus aureus Isolated from a Case of Foodborne Outbreak in Bulgaria
Authors: Ivanova Teodora , Krumova-Valcheva Gergana , Mateva Gergana , Daskalov Hristo
Published: October 2020

This paper presents an outbreak provoked by methicillin-resistant strains of coagulase-positive S. aureus (CPS), produced staphylococcal enterotoxins (se) in pig meatballs and potato salad consumed from 70 people in the village Mamarchevo, Bulgaria. Eighteen women aged 50 to 70 years, and two children aged 4 and 5 years have demonstrated a severe malaise with vomiting and indigestion. Two food samples and isolates of CPS were received in the laboratory of Bulgarian Food Safety Agency. Both samples were found to have a high level of CPS. The level of S. aureus contamination in the potato salad was 8.3 logs CFU/g and 7.7 logs CFU/g in roasted meatballs, which was a significant reason to doubt the production of the toxin. The samples were analyzed according to the European Screening Method v5 using mini VIDAS SET2. The results showed a presence of staphylococcal enterotoxin (TV 2.67 for meatballs and TV 3.27 for potato salad), which was the reason for the ensuing food intoxication. EURL CPS applying quantitative indirect sandwich-type ELISA confirmed the presence of sea, sec and sed in the potato salad and sea and sed in the roasted meatballs. Two CPS isolates were confirmed as S. aureus by a species-specific 23S rRNA targeted PCR test. Real-time PCR method detected sea, sed, seg, sei, sej, and ser genes in S. aureus strains, found in both matrixes. Multiplex PCR method proved the existence of the mecA gene in both S. aureus strains. Resistance to cefoxitin (>16 mg/L), penicillin (>2 mg/L), kanamycin (64 mg/L) and sulfamethoxazole (>512 mg/L) was found.
Swiss second-home owners’ intentions of changing housing patterns
Authors: Sarman Igor , Czarnecki Adam
Published: October 2020

For several decades, second homes have gained popularity across Europe. For various socio-economic reasons, it is important to understand the factors prompting owners to migrate to the destination area or preventing them from doing so. Discussions about “home” and “migration” here consider the emerging explanatory opportunities brought about by the “new mobility paradigm”. The purpose of this work is to examine whether second-home owners are prone to switch their housing pattern, hence permanently move to their second home, or to maintain the status quo, following a more flexible lifestyle by using both homes. An empirical investigation aimed at identifying the key factors fostering second-home owners’ intentions of future relocation to a holiday destination is proposed. Individual observations were collected through a survey posted to second-home owners in the Lake Maggiore region (Southern Switzerland). Results show that most of the second-home owners are happy to continue their current flexible housing patterns and enjoy the best of both homes, rather than opting for permanent relocation. This study also demonstrates the importance of the owner’s socio-demographic and psychological traits, as well as objective and subjective host-community characteristics, in explaining individuals’ future housing intentions.
Justice Reform or Facade Reform: The case of the Western Balkans
Authors: Halili Zenun
Published: October 2020

EU transformative power is put into question and constantly challenged by the political actions of leaders in the Western Balkans. Although the political elites in this region have internalised a pro-European discourse, they are still guided and governed by authoritarian logic and practices colliding with the EU’s governing model. The paper analyses precisely this relationship between the EU and internal politics, namely, the transformative power/powerlessness of the EU towards the aspiring countries for membership in a single dimension; namely, justice. The paper reviews the reforms developed and the effects they have produced in the justice system in a calculation relation: costs and benefits. In this logic, this paper analyses costs and benefits of the internal elites of the Western Balkans, representing a classic oxymoron. On the one hand, pro-EU discourse is superficially used and, on the other, substantive actions are far from the EU’s governing model. The central argument emphasises that the reform process in the region has turned into a repetitive system of itself and destined to fail right from the beginning. So, we see a loss in reforms and plunging into a vicious circle, whereby each time elements increase and intensify but deteriorate one another, inevitably leading to the deterioration of the situation and producing multidimensional corruption.
Suicide attempts at the age of 10-18 in Lublin
Authors: Pabiś Małgorzata , Augustowska-Kruszyńska Kinga
Published: October 2020

Introduction. The number of children and adolescents hospitalized due to suicide attempts caused by stress, low self-esteem, lack of acceptance and peer violence, as well as family problems, increases every year. In addition, there may occur disturbed self-perception or depression. This is a very complex phenomenon, the scale of which should induce immediate multidimensional activities.

Aim. Analysis of the occurrence of suicide attempts among minors on the example of the city of Lublin.

Material and methods. The statistical data obtained from the Polish Police Headquarter and from the report of the Foundation We Give Children Strength – “Children count 2017” was analyzed and a review of the literature on the subject for the years 2014-2018 developed using the descriptive method was made.

Results. The report of the Foundation We Give Children Strength shows a huge scale of the phenomenon. According to its data, as many as 72% of children aged 11-17 have experienced at least one form of abuse in their lives, 7% of respondents have attempted suicide, and 16% of teenagers have mutilated themselves. The statistics conducted in Poland in 2017-2018 recorded: in 2017 the number of 116, and in 2018 – 97 suicide attempts ended in death. There were 5 deaths in 2017 and 9 in 2018 in Lubelskie Voivodeship, what shows an increase by 80% in 12 months. In the 7-12 age group in 2017, only one suicide attempt ended up in death was reported, in 2018 the number increased to 5 – none of them concerned the Lublin Province.

Conclusions. Suicide attempts ending up in death in 2018 accounted for 2.30% of suicide attempts undertaken in Lublin, while in Poland they constituted 1.87%. The main reasons for suicide attempts among minors are: the lack of acceptance, low self-esteem and peer violence, both physical and mental. Mass media have an influence on juvenile suicides. Belief in “multiple lives” perpetuated by computer games and films can have an impact on suicide attempts.
Investigation of the inhibitory-bactericidal effect of amidoamine-based inorganic complexes against microbiological and atmospheric corrosion
Authors: Aghazada Y.J. , Abbasov V.M. , Mursalov N.I. , Abdullayev S.E. , Yolchuyeva U.J.
Published: October 2020

In the process, inorganic complexes of amidoamines obtained from the interaction of natural petroleum acid and oleic acids with diethylenetriamine have been developed and their effectiveness as inhibitor-bactericides has been investigated. The effect of the synthesized reagents on the kinetics of the corrosion process of steel and the activity of sulphate-reducing bacteria in 3% NaCl solution saturated with CO2 and in the biphasic water–isopropyl alcohol medium with H2S dissolved has been analyzed. The thermodynamic and kinetic parameters of the corrosion process were calculated. The adsorption of the complexes was investigated using the Langmuir isotherm and the correlation constant was determined. State of the metal surface was investigated by SEM method in CO2 and H2S media, with and without inhibitors, and the metal surface contact of complexes was studied by computer molecular simulation.
Enzymatic extraction of potato starch: A parametric optimization study using response surface methodology
Authors: Hameed Madsar , Ahmad Syed W. , Ahmad Sajjad , Qutab Haji G. , Dasih Muhammad , Imran Muhammad
Published: October 2020

Optimized, effective and efficient methodology has been determined in this research work for the recovery of starch from potatoes. Potato starch extraction experimental results have been utilized for the parametric optimization study by using different statistical techniques. In this research work, starch extraction was conducted by employing cellulase enzyme. Response surface methodology (RSM) was put to use to perform statistical analysis to get optimum results. Five-level central composite design (CCD) consisting of three parameters was implemented to investigate the effect of enzyme concentration, contact time and broth dilution. Experiment results revealed that increment in enzyme concentration and contact time enhanced the starch recovery while dilution showed the inverse relation on the recovery of starch. Optimum starch recovery was achieved upto 89% when enzyme concentration (0.5 g/100 g) of potato meal was diluted with 10 mL of water and mixed for 4 h at 45°C.
Odour emission from primary settling tanks after air-tightening
Authors: Friedrich Małgorzata , Mizerna-Nowotna Paulina , Latzke Filip
Published: October 2020

The purpose of the present article was to determine odour emission rate from primary settling tanks after hermetisation. The paper presents the results of the research on odour emission from four settling tanks, covered with self-supporting aluminium domes with a diameter of 52 meters, located on urban wastewater treatment plants, with the planned flow capacity equal to 200 000 m3/day. Altogether, the olfactometry analysis of 189 samples of polluted air pulled from the domes with the use of an air blower which has efficiency of 12 000 m3/h was conducted. The results of odour concentration measurements were in a range of approximately 10 800 to 763 600 ouE/m3. Average odour emission rate was equal to 102 ouE/(s · m2). The obtained value is much higher than the literature data, available for non-hermetised settlers only. This rate enables better estimation of the odour stream that has to be deodorised after sealing the settling tanks.
Using Social Media Data to Plan for Tourism
Authors: Zajadacz Alina , Minkwitz Aleksandra
Published: October 2020

The purpose of the article is to present the concept of using social media (SM) as data sources and communication tools, useful at the various stages of planning, implementing and monitoring the effects of tourism development on a local level. The first part discusses the stages of planning, then presents the characteristics of SM, along with a discussion of the issues presented in the literature to this date. The next part presents data sources and methods of research on SM and functions that they can perform in tourism. The concept presented, on the one hand, reviews the perspectives of practical use of SM as a communication tool and source of data and, on the other hand, the challenges related to the need to further deepen research on tourism planning methods that are adequate to the continuously changing environment.
Groundwater Level Prediction through GMS Software – Case Study of Karvan Area, Iran
Authors: Bayat Mandana , Eslamian Saeid , Shams Gholamreza , Hajiannia Alborz
Published: October 2020

Iran, being located in arid and semi-arid regions, faces an increase in human demand for water, and the global climate change has led to the excessive use of groundwater. China, India and Iran were ranked from first to third, respectively, in excessive groundwater consumption in 2005. The effects of effective parameters on groundwater recharge such as precipitation, surface recharge and well water harvesting in the Karvan aquifer are assessed. Groundwater flow models have typically been and are being adopted since the beginning of this millennium to better manage groundwater resources. The decrease in groundwater level and the potential environmental hazards thereof have made the researchers here to apply the Groundwater Modelling System (GMS software) in 3D in the subject area. This modelling is calibrated and validated for 86 months at steady and unsteady states. In this study, six scenarios are defined as both an increase and a decrease of 30% in precipitation, both an increase and a decrease of 30% in surface recharge, an increase of 10% in well water harvesting and a decrease of 30% in well water harvesting. The best scenario is selected for the subject area water management.
Modern treatment of vulvar cancer
Authors: Merlo Sebastjan
Published: October 2020

Background

Vulvar cancer accounts for 3–5% of malignant diseases of the female genital tract. The Slovenian incidence rate is 5.5/100,000, which means 57 new cases per year. The most common histological type (90%) is squamous cell carcinoma. Based on etiology, it can be classified into the first type which correlates with human papillomavirus (HPV) infection and the second type which is not associated with HPV. The most common and long-lasting symptom of vulvar cancer is pruritus. The preferred diagnostic procedure to confirm the diagnosis is a punch or incision biopsy. Surgery in combination with radiotherapy is the standard treatment for vulvar cancer. Sentinel lymph node biopsy with lymphoscintigraphy is now a standard part of surgical treatment. Chemotherapy is a palliative treatment option.

Conclusions

Vulvar cancer is a rare disease. Because of the pathogenesis, surgery and radiotherapy are the main treatment modalities. The sentinel node biopsy (SNB) represents a contemporary approach to the vulvar cancer treatment and significantly reduces morbidity. Improvements in treatment of vulvar cancer contributed to the decrease of mortality among Slovenian women.
Neutrophil-to-lymphocyte ratio can predict outcome in extensive-stage small cell lung cancer
Authors: Drpa Gordana , Sutic Maja , Baranasic Jurica , Jakopovic Marko , Samarzija Miroslav , Kukulj Suzana , Knezevic Jelena
Published: October 2020

Background

The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) were analyzed in various carcinomas and their potential prognostic significance was determined. The objective of present study was to determine the correlation between these parameters and the survival of patients with small cell lung cancer (SCLC), since very few studies have been published on this type of carcinoma.

Patients and methods

One hundred and forty patients diagnosed with SCLC at University Hospital Center Zagreb, between 2012 and 2016 were retrospectively analyzed. Extensive-stage disease (ED) was verified in 80 patients and limited-stage disease (LD) in 60 patients. We analyzed the potential prognostic significance of various laboratory parameters, including NLR, PLR, and LMR, measured before the start of treatment.

Results

Disease extension, response to therapy, chest irradiation and prophylactic cranial irradiation (PCI), as well as hemoglobin, monocyte count, C-reactive protein (CRP), and lactate dehydrogenase (LDH) showed a prognostic significance in all patients. When we analyzed the patients separately, depending on the disease extension, we found that only skin metastases as well as LDH and NLR values, regardless of the cut-off value, had a prognostic significance in ED. Meanwhile, the ECOG performance status, chest irradiation, PCI, and hemoglobin and creatinine values had a prognostic significance in LD.

Conclusions

NLR calculated before the start of the treatment had a prognostic significance for ED, while PLR and LMR had no prognostic significance in any of the analyzed groups of patients.
Treatment patterns and real-world evidence for stage III non-small cell lung cancer in Central and Eastern Europe
Authors: Zemanova Milada , Jakopovic Marko , Stanic Karmen , Łazar-Poniatowska Małgorzata , Vrankar Martina , Rusu Petronela , Ciuleanu Tudor , Radosavljevic Davorin , Bogos Krisztina , Nawrocki Sergiusz
Published: October 2020

Background

The aim of this project was to collect real-world evidence and describe treatment patterns for stage III non-small cell lung cancer in Central and Eastern Europe. Based on real-world evidence, an expert opinion was developed, and the unmet needs and quality indicators were identified.

Patients and methods

A systematic literature search and a multidisciplinary expert panel of 10 physicians from 7 countries used a modified Delphi process to identify quality indicators and unmet needs in patients with stage III non-small cell lung cancer. The profound questionnaire was used to characterize treatment patterns used for stage III non-small cell lung cancer, and a systematic review identified patterns in Central and Eastern Europe. The first questionnaire was completed by a group of medical oncologists, radiation oncologists and pneumologists. The panel of experts attended an in-person meeting to review the results of the questionnaire and to process a second round Delphi. An additional survey was then compiled and completed by the panel.

Results

A complete consensus was reached by the panel of experts on a set of evidence-based clinical recommendations. The experience-based questionnaire generated a highly variable map of treatment patterns within the region. A list of unmet needs and barriers to quality care were developed with near-unanimous consent of the panel of experts.

Conclusions

The current landscape of diagnostic and therapeutic approaches in Central and Eastern European countries is highly variable. We identified several significant barriers, mainly related to the availability of diagnostic and imaging methods and low rates of chemoradiotherapy with curative intention as initial treatment for unresectable stage III NSCLC.
Categorization of the EU Member States in the Context of Selected Multicriteria International Indices Using Cluster Analysis
Authors: Onuferová Erika , Čabinová Veronika , Matijová Mária
Published: October 2020

The main aim of the paper was to analyse the economic and social development of the European Union (EU) member states (28 countries) on the basis of selected five multicriteria indices (the Global Competitiveness Index, the Economic Freedom Index, the Global Innovation Index, the Corruption Perceptions Index, the Human Development Index). To perform settled aim, a multidimensional classification of EU countries for years 2011 and 2018 using cluster analysis was realized. The purpose of the analysis was to categorize the individual EU countries into clusters and to find out to what extent the position of EU member states has changed in terms of selected international indices over the analysed period. Based on the findings, it is arguable that a major part of the EU member states cluster into the same groups based on the selected indices assessment, regardless of the time period. However, six countries (Czech Republic, Estonia, Germany, Latvia, Lithuania, and United Kingdom) improved their position during the period under review and ranked into the cluster of more prosperous countries in 2018. The rate of change (improvement) was quantified at the level of 21.43%. Based on the results, Latvia and Lithuania were the most similar countries in terms of economic prosperity (Euclidean distance reached the level of 3.08), while the least similar countries were Greece and Sweden (Euclidean distance reached the level of 70.8). Declining Euclidean distances indicate that economic disparities of the individual EU countries have decreased in the period under review. This paper aims at developing the research to find out how, besides hierarchy, we can analyse the EU member states from the perspective of various multicriteria indices. The four proposed clusters could be used as a starting point for future policy reforms, pointing to the weaknesses of various countries.
Influence of the heterogeneity of a dump soil on the assessment of its selected properties
Authors: Olesiak Sebastian
Published: October 2020

This article concerns the assessment of selected physical and mechanical properties of a dump soil. The dump soil is a specific soil with a very heterogeneous internal structure. Next to each other, there may be lumps and crumbs of cohesive soils mixed with non-cohesive soils accompanied by a very diverse admixture of organic substance. In addition, the soil in the waste dump, in spatial terms, may significantly differ in consistency and density. This is the result of the process of forming a dump soil, which takes place in three stages: excavation, transport and dumping. A heterogeneous soil deposited within the waste dump is subject to further processes: consolidation, compaction and creeping. Changes occurring in the course of these processes have a significant impact on the development of the properties of the dump soil.

Due to the large diversity of the tested soils, the results of their properties were divided into two groups, based on type and consistency of soil. This allows us to estimate the selected properties of the dump soil only on the basis of their macroscopic analysis.
Statistical analysis of mechanical properties on the example of aggregates of Carpathian sandstones
Authors: Hydzik-Wiśniewska Joanna , Bednarek Łukasz
Published: October 2020

The constantly growing, broadly understood, construction industry requires the use of a large amount of aggregates. The construction of roads, motorways, railway lines and hydrotechnical structures requires the use of aggregates of high quality, which is primarily determined by mechanical properties. The basic parameters describing mechanical properties of aggregates are the Los Angeles (LA) fragmentation resistance coefficient and the Micro-Deval (M

DE
) abrasion resistance coefficient. The LA and M

DE
coefficients depend mainly on the type of rock and its physical and mechanical properties. This has been thoroughly researched and documented as evidenced by the abundant literature in the field. However, the correlation between LA and M

DE
coefficients still gives rise to extensive discussions and some concerns. A number of publications demonstrate dependencies for various types of aggregates. Therefore, research was undertaken to present statistical analysis for one type of aggregate and one geological area.

This article presents the results of the fragmentation resistance test in the Los Angeles drum and the abrasion resistance test in the Micro-Deval drum of aggregates from Carpathian sandstone deposits. Aggregate samples were divided into three groups according to the location of the deposits and the tectonic unit from which they originated. The obtained results were subjected to static analysis to fit the best mathematical function describing the relationship between the two parameters.
Using Triaxial Tests to Determine the Shearing Strength of Geogrid-Reinforced Sand
Authors: Skuodis Šarūnas , Dirgėlienė Neringa , Medzvieckas Jurgis
Published: October 2020

Geogrids are widely used in civil engineering projects to reinforce road and railway structures. This paper presents research on the shearing strength of soil samples that have been reinforced with geogrids. The relationship between soil and geogrids is explored and evaluated by modeling the mechanical behavior of heterogeneous materials. For the purposes of this research, data obtained from tests of unreinforced sand samples with triaxial cells were compared with the data obtained from tests of reinforced sand samples. It was found that the shearing strength for reinforced samples was higher (from 9% to 49%) compared to unreinforced samples. Some damage to the geogrid was detected during the experiment, and for this reason, the same tests were numerically simulated for both unreinforced samples and samples reinforced with geogrids. Numerical simulations revealed the main reasons for damage to the geogrids during triaxial testing.
Sokolism in Leskovac and Vlasotince
Authors: Stamenković Miloš
Published: October 2020

The Sokol movement originated in Prague on February 16, 1862, under the then Habsburg Monarchy, as a form of awakening Czech national consciousness through sporting activities. The conceptual creator of this concept was Miroslav Tirsh, and together with him the founders of the Exercise Organization ''Soko'' were Jindrich Finger and Emanuel Toner. Serbian sokolism developed later, on several sides, according to circumstances and circumstances in which the situation was different in the free Principality, then in the Kingdom of Serbia, and differently in the areas where Serbs under the Austro-Hungarian monarchy lived. Sokolism in the south of Serbia arose from gymnastics, which was the ,,key point'' of the work of both the Gymnastics and later Sokol society. A special impetus for mass membership in southern Serbia was given by Uros, son of Proka Crnilovic, from Vlasotince at Belgrade studies, who in 1911 participated with the sokols from Belgrade at the AllSokol Slet in Zagreb, and even more by participating in the All-Sokol Slet in Prague 1912, when he won the medal in the long jump. The aim of this research was to find out and present historical facts about the occurrence of sokolism in the south of Serbia, especially in Leskovac and Vlasotince.
“The Darts to Wound With Endless Love!” on Hannah Cowley’s Response to Frances Burney’s Evelina
Authors: Paluchowska-Messing Anna
Published: October 2020

The paper traces the intertextual echoes of Frances Burney’s debut novel, Evelina, in The Belle’s Stratagem, a play by Burney’s contemporary Hannah Cowley. The latter was certainly an avid admirer of Burney. In one of her poems she pays tribute to the novelist and praises her ability to achieve uncommon subtlety in the depiction of characters in her writing: “What pen but Burney’s …/… draws from nature with a skill so true” (Escott 2012: 38). The paper, however, argues that the connection between the writers and their literary productions goes much further than the obeisance paid to Burney in Cowley’s admiring verses. The congruence between the plots of Evelina and The Belle’s Stratagem, and, in some instances, the very wording used in the two texts, poses immediate questions about its significance in Cowley’s popular play (which was first produced in 1780, two years after the publication of Burney’s debut). The conclusions suggest that Cowley deliberately drew Burney’s novel into a discussion on viable models of femininity and matrimony in contemporary society. But they also point to a wider phenomenon, namely, the extent to which the relationship between the eighteenth-century theatre and novel was reciprocal. While several recent studies discuss the influence of the theatre on the novel, little has been said on the importance of the novel for the development of the contemporary drama. This new reading of Cowley’s The Belle’s Stratagem as a response to Burney’s Evelina shows the immediacy with which a literary dialogue could be opened by authors and appreciated by audiences on the vibrant eighteenth-century cultural scene.
The Middle English Creolization Hypothesis: Persistence, Implications, and Language Ideology
Authors: O’Neil David
Published: October 2020

Bailey and Maroldt (1977) and Domingue (1977) were the first to argue that language contact during the Middle Ages between Old English and both Old Norse and Norman French resulted in linguistic creolization. This theory, known as the Middle English creolization hypothesis, implies that Middle English, and perhaps Modern English as well, should be classified as a creole. Though frequently discredited on historic, linguistic, and terminological grounds, the creolization hypothesis has attracted interest for longer than might be expected. This paper argues that the persistence of the hypothesis may be ideologically motivated. The first section examines connotations of the term “creole” and applies these connotations to an analysis of the initial presentations of the creolization hypothesis. The second and third section of the paper review and analyze the forty-year history of the debate, focusing separately on arguments for creolization (and koinezation) between Anglo-Norman French and Old Norse, respectively. The fourth and final section examines challenges presented by the concept of creole exceptionalism to common attitudes about language equality and the theory of Universal Grammar. It is argued that these issues attract greater interest when contextualized within a discussion of a “major” world language such as English than when creolization is understood as an atypical process restricted to “peripheral” languages such as Haitian Creole. This paper also references relevant political issues such as the current controversy among medievalists about the field’s historic lack of inclusivity.
Simpanan Karbon Padang Lamun di Kawasan Pantai Nusa Lembongan, Klungkung, Bali
Authors: Negara I Ketut Suta , Astawa Karang I Wayan Gede , Giri Putra I Nyoman
Published: October 2020

The seagrass ecosystem has great potential in absorbing of CO2 concentration in atmosphere, results of the process photosynthesis will be stored in form of biomass during seagrass still alive. The research purpose was to know carbon storage from the seagrass ecosystem at the top substrate (leaves) and bottom substrates (rhizome and roots) in Nusa Lembongan coastal area, Bali. The research location is divided into three stations with 27 points. Carbon stock was analyzed by using invasion method consisting of calculating the value of ash content, organic matter content and carbon content. The results found three seagrass species in the Nusa Lembongan coastal area: Thalassia hemprichii, Cymodocea rotundata and Enhalus acoroides. The most dominant spesies is the Thalassia hemprichii. The carbon stored at the top substrate (leaf) is 21.08 gC/m2 and the bottom substrates (rhizome and root) are 52.67 gC/m2. The total estimated carbon deposits in the Nusa Lembongan coastal area is 65.98 tonnes with carbon deposits in the bottom substrate are larger than the top substrate, which is 71% or 47.12 tons on the bottom substrate while 29% or 18.86 tons on the top substrate.
HUBUNGAN PERSENTASE LEMAK TUBUH DAN IMT DENGAN KEKUATAN OTOT GENGGAM PADA REMAJA PUTRI USIA 15-17 TAHUN DI SMK KESEHATAN BALI MEDIKA DENPASAR
Authors: Savitri I Gusti Agung Ayu Narita , Winaya I Made Niko , Muliarta I Made , Griadhi I Putu Adiartha
Published: October 2020

Kekuatan otot genggam adalah salah satu elemen penting dalam melakukan aktivitas. Tujuan penelitian ini adalah untuk mengetahui hubungan antara persentase lemak tubuh dan IMT dengan kekuatan otot genggam pada remaja putri  usia 15-17 tahun di SMK Kesehatan Bali Medika Denpasar. Penelitian ini merupakan penelitian cross sectional analytic yang dilakukan pada April 2019. Sample diambil dengan teknik Simple Random Sampling dengan sampel berjumlah 85 orang. Uji hipotesis yang digunakan adalah Chi Square Test dan didapatkan hasil nilai p 0,002 untuk hubungan kekuatan otot genggam dengan persentase lemak tubuh, dan p 0,024 untuk hubungan dengan IMT, atau p<0,05. Prevalence Ratio remaja memiliki kekuatan otot genggam kategori lemah adalah 4,073 [95% CI 1,629-10,186] untuk kategori persentase lemak overweight dan obesitas dibandingkan kategori good dan acceptable serta 2,771 [95% CI 1,128-6,808] untuk perbandingan kategori IMT obesitas dan gemuk dengan kategori normal. Berdasarkan hasil penelitian maka dapat disimpulkan terdapat hubungan antara persentase lemak tubuh dengan kekuatan otot genggam, dan hubungan antara IMT dengan kekuatan otot genggam pada remaja putri usia 15-17 tahun di SMK Kesehatan Bali Medika Denpasar. Kategori overweight dan obesitas memiliki risiko 4,073 kali lebih tinggi berkategori otot genggam lemah dibandingkan kategori persentase lemak good dan acceptable, dan kategori IMT gemuk dan obesitas memiliki risiko berkategori kekuatan otot genggam lemah 2,771 kali lebih tinggi dibandingkan dengan seseorang berkategori IMT normal.
An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration
Authors: Martinez Marta De Castro , Maza Cristina Castillo
Published: October 2020

Background:

The main use of Granulocyte colony stimulating factor (G-CSF) is stem cell mobilization in neutropenic patients and healthy donors as well as for engraftment. Most of their secondary efects are mild and temporary; however, there is a relation between spontaneous splenic rupture and G-CSF treatment.

Case Presentation:

We report a case of an 88-year old man, who presented with a spontaneous splenic rupture after use of G-CSF.

Conclusion:

Although it is an uncommon side effect, the mortality is very high, so clinicians should be aware of the importance about maintaining a high index of suspicion for this condition.
Group Cohesiveness on Performance: Mediating Effect of Collective Organization Citizenship Behavior
Authors: Nur L. Fikriah Ikhsan Maksum, T. Hani Handoko,
Published: October 2020

Organizational Citizenship Behavior towards Organizations (OCBO) concerning the organization's benefits in general and Organizational Citizenship Behavior towards Individuals (OCBI) concerning specific benefits obtained by individuals in the organization and contributes to the organization. The research aims to examine the role of mediating the collective organizational citizenship behavior on the influence of group cohesiveness on group performance based on social exchange theory and social identity theory. The object of research is working groups on the creative industries in Yogyakarta. The study used field settings and cross-sectional study designs. Research respondents were 39 working groups consisting of 300 group members and using the regression analysis technique as a research hypothesis testing technique. The results showed that collective organizational citizenship behavior (OCBO and OCBI) partially mediated the effect of group cohesiveness on group performance.
Transdisciplina y multidimensionalidad: una visión desde el contexto educativo
Authors: Suaza Jimenez Jorge Hernan
Published: October 2020

Las nuevas formas de pensamiento dan lugar a ciencias que se dedican a su comprensión. El pensamiento complejo y los problemas como sistemas complejos se pueden observar desde el punto de vista de lo multidimensional y desde la necesidad de incorporar múltiples disciplinas para hacerles frente. Esta no es una excepción en el contexto educativo, donde los estudiantes tienen múltiples formas y estilos de aprendizaje y se tiene el propósito de mejorar la forma en que se comprende el mundo de forma sistemática. Aun así, muchas instituciones no están preparadas para ello. Por ende, se definen los conceptos de transdisciplina y multidimensionalidad y se analiza, en cada uno, su importancia en la solución de problemas reales desde la teoría de la complejidad.
La noción de Educación de Calidad a nivel superior: una reflexión crítica desde el discurso del desarrollo
Authors: Clara Zafra Miguel Ángel , Vega Zárate César
Published: October 2020

En esta investigación se presenta una reflexión acerca de la noción de educación de calidad en la educación superior desde las teorías que constituyen el discurso del desarrollo. Este preámbulo es la pauta que sirve para abordar la importancia de la educación superior para el desarrollo de los países, y como la acreditación juega un papel protagónico del mismo discurso. Además, se reflexiona la educación de calidad desde los Objetivos de Desarrollo Sostenible de la agenda 2030.
Caracterización de los métodos y estrategias pedagógicas básicas en el proceso de motivación del niño en el nivel de preescolar en instituciones educativas de la ciudad de Neiva
Authors: Celeita Buitrago Laura Estefany , Pérez Gutiérrez María Fernanda
Published: October 2020

Este artículo presenta los resultados de la investigación «Caracterización de los métodos y estrategias pedagógicas básicas en el proceso de motivación del niño en el nivel de preescolar», la cual involucró a 10 instituciones educativas 5 del sector oficial y 5 del sector privado. El trabajo de campo implicó la implementación de instrumentos como, la realización de entrevistas a directivos y docentes, registros de observación de las clases y el registro documental.El objetivo central de la investigación es plantear una propuesta de intervención a las instituciones tanto del sector oficial como del sector privado, que permita consolidar los métodos y las estrategias pedagógicas que garanticen la motivación en el niño de preescolar y permita la obtención de un buen nivel formativo y educativo.
Factores que influyeron en la decisión de crear empresas en neiva: Treinta años pensando en el futuro
Authors: Huergo Tobar Pedro Luis
Published: October 2020

El contexto nacional influye en las empresas desde su misma creación impactando de manera directa en la economía nacional. En esta investigación las empresas fueron estudiadas desde su contexto, tomando el pensamiento individual del empresario; se analizaron los factores más influyentes en la toma de decisión de crear empresas en Neiva por el periodo 1973 a 2003. La investigación buscó sistematizar la información a partir del análisis estadístico y datos cuantitativos utilizando técnicas descriptivas. El universo estuvo conformado por 24.201 firmas, se tuvo en cuenta los factores individual, familiar, social y económico. Se concluye de manera general que los agentes generadores fueron: Ofrecer un mejor futuro a su descendencia, voluntad de prestar un servicio a la comunidad, preparación académica enfocada a cultura emprendedora, asegurar su futuro e indiscutiblemente, identificación de oportunidades de negocio.
PERAN FORUM KERUKUNAN UMAT BERAGAMA DALAM MENINGKATKAN KUALITAS SIKAP HIDUP TOLERANSI ANTAR UMAT BERAGAMA DI KOTA KUPANG
Authors: Taopan Nimrod Frebdes , Ly Petrus , Lobo Leonard
Published: October 2020

Penelitian ini dilaksanakan dengan tujuan: Mendeskripsikan program kerja FKUB sebagai bentuk usaha meningkatkan kualitas sikap toleransi. Mendeskripsikan hambatan dalam mengimplementasikan program Kerja FKUB. Mendeskripsikan upaya mengatasi hambatan dan Mendeskripsikan kualitas sikap toleransi antar umat beragama di Kota Kupang. Metode yang digunakan dalam penelitian ini adalah metode kualitatif bersifat deskriptif, teknik pengumpulan data berupa wawancara dan studi dokumen. Hasil penelitian ini menunjukan bahwa:1) Peran FKUB NTT dalam membangun toleransi umat beragama di Kota Kupang dilakukan dengan program rutin dalam bentuk dialog, seminar, sosialisasi, lomba pidato serta lomba Hyme dan mars kerukunan, program tidak rutin dalam bentuk penerbitan buku, pembuatan striker, kalender dan spanduk keagamaan. 2) Terdapat hambatan berupa kesibukan dari pemuka agama sehingga rapat belum berjalan secara baik, komunikasi dalam rapat juga hanya terjadi setiap ada rapat dan terbatasnya fasilitas serta Pemerintah maupun masyarakat belum menyadari peran dari FKUB NTT.3) Upaya mengatasi hambatan dilakukan dengan diskusi antar badan pengurus, komunikasi dengan pemerintah, sosialisasi, membuat proposal dan menghemat dana sesuai dengan kebutuhan.4) Kerukunan di Kota Kupang berjalan dengan baik tanpa ada konflik keagamaan disebabkan kerukunan yang ada di Kota Kupang merupakan warisan dari leluhur yang terus dijaga dan dikembangkan hingga saat ini. Kata Kunci: Peran, Forum Kerukunan Umat Beragama, Toleransi Beragama
Click Activated Protodrugs Against Cancer Increase the Therapeutic Potential of Chemotherapy through Local Capture and Activation
Authors: Wu Kui , Yee Nathan , Srinivasan Sangeetha , Mahmoodi Amir , Zakharian Michael , Mejia Oneto Jose M. , Royzen Maksim
Published: October 2020

A desired goal of targeted cancer treatments is to achieve high tumor specificity with minimal side effects. Despite recent advances, this remains difficult to achieve in practice as most approaches rely on biomarkers or physiological differences between malignant and healthy tissue, and thus benefit only a subset of patients in need of treatment. To address this unmet need, we introduced a Click Activated Protodrugs Against Cancer (CAPAC) platform that enables targeted activation of drugs at a specific site in the body, i.e., a tumor. In contrast to antibodies (mAbs, ADCs) and other targeted approaches, the mechanism of action is based on in vivo click chemistry, and is thus independent of tumor biomarker expression or factors such as enzymatic activity, pH, or oxygen levels. The platform consists of a tetrazine-modified sodium hyaluronate-based biopolymer injected at a tumor site, followed by one or more doses of a trans-cyclooctene (TCO)- modified cytotoxic protodrug with attenuated activity administered systemically. The protodrug is captured locally by the biopolymer through an inverse electron-demand Diels-Alder reaction between tetrazine and TCO, followed by conversion to the active drug directly at the tumor site, thereby overcoming the systemic limitations of conventional chemotherapy or the need for specific biomarkers of traditional targeted therapy. Here, TCO-modified protodrugs of four prominent cytotoxics (doxorubicin, paclitaxel, etoposide and gemcitabine) are used, highlighting the modularity of the CAPAC platform. In vitro evaluation of cytotoxicity, solubility, stability and activation rendered the protodrug of doxorubicin, SQP33, as the most promising candidate for in vivo studies. Studies in rodents show that a single injection of the tetrazine-modified biopolymer, SQL70, efficiently captures SQP33 protodrug doses given at 10.8-times the maximum tolerated dose of conventional doxorubicin with greatly reduced systemic toxicity.
Transmission of covid 19 through eyes — Review article
Authors: Shivani Sanjay Ingole  , Roshna Bhutada
Published: October 2020

The Corona virus Covid19 is a severe respiratory disorder which is caused due to infection, previously known as 2019-nCoV. The infection is caused due to the contagious virus, which leads to a severe respiratory disease known as COVID-19. Patients who are suffering from conjunctivitis, fever, cough and shortness of breath and those who traveled from hots spot area of corona virus or their family members are suffering from corona virus come to an ophthalmologist could be the patient suffering from corona virus or may have an infection due to covid19. Conjunctivitis patients coming from regions with a high prevalence of COVID-19, come to an ophthalmologist could be suffered from corona virus. The corona virus genome is a single-stranded RNA that causes COVID-19. The corona virus is a contagious disease which spreads from person to person through their respiratory droplets of an infected person after their coughing and sneezing. A healthy person could be infected by corona virus if people touch an object or surface with virus present from an infected person, and then touch their mouth, nose or eyes. In some recent articles and reports, it is suggested that corona virus can cause conjunctivitis either as an early sign or during hospitalization during severe covid19. There are chances of spreading of corona virus to eyes through aerosols or due to hands to eye contact. Covid19 patients have single-stranded RNA virus throughout the body and also in the tears of eyes, but there is no evidence of corona virus cultured in the conjunctiva of eyes. Conjunctiva congestion and conjunctivitis are found in patients having confirmed diagnosis of covid19.
RECONCEPTUALISING BUSINESS-IT ALIGNMENT FOR ENABLING ORGANISATIONAL AGILITY
Authors: Horlach Bettina , Drews Paul , Drechsler Andreas , Schirmer Ingrid , Boehmann Tilo
Published: October 2020

No description supplied
Trialling a Comparative Assessment Tool for Modelling-oriented Assignments – Findings and Recommendations
Authors: Drechsler Andreas
Published: October 2020

No description supplied
Designing for Change and Transformation: Exploring Artefact Generativity
Authors: Drechsler Andreas
Published: October 2020

© ACIS 2017. This paper explores artefact generativity as a novel conceptual frame to inform information system (IS) artefact design beyond designing for artefact utility at the time of an artefact's introduction or implementation. The paper draws on three recently developed generativity conceptualizations and applies the findings to IS artefact design. Artefact generativity captures the notions that 1) sustained artefact utility may require potentially continuous artefact changes over its lifetime, 2) (re-)designers need to enact these changes within a design system, and 3) continuous artefact use may lead to further generative transformations in the artefact's social and technical environment. IS design science researchers can draw on this paper's findings to inform future artefact design decisions that address these three notions by drawing on the established and growing foundations of IS and social science theories that underlie the established generativity perspectives.
Towards a Model for Discourse Ethics-based Digital Business Strategy Development
Authors: Degner O , Drechsler Andreas
Published: October 2020

© 2016 Oliver Degner & Andreas Drechsler. We develop a decision-making process model that implements generic discourse ethics and business ethics proposals specifically for ethical digital business strategy (DBS) development. The model’s objective is to answer the question how DBS initiatives – with the potential to affect the wider society – can be developed and justified considering economic, ecological and social criteria, based on consensus among the relevant stakeholders. We evaluate the model by examining two past DBS initiatives that were reported in the media as being controversial because of a lack of stakeholder consensus. With the model, we contribute a pragmatization of the business and discourse ethics literature for the IS discipline that covers the time before actual IS design and development decisions take place. Business and IT executives in practice can draw on the model to guide their DBS processes along ethical lines.
Tough choices for an agile open source international development project: the Libre LAS Case
Authors: McDowell A , Drechsler Andreas
Published: October 2020

© 2017, Association for Information Technology Trust. In June 2010, the Food and Agriculture Organization (FAO) of the United Nations (UN) started a three-year trust fund project to develop and pilot open source cadastre and registration software. This project was called Libre Land Administration System (Libre LAS), and its aim was to make computerised cadastre and registration systems more affordable and more sustainable in developing countries. The first stage of the Libre LAS project was undertaken at FAO headquarters (HQ) in Rome. Generic cadastre and registration processes were defined and software requirements and software architecture documents prepared. Development of the Libre LAS software began in early 2011. An international team of software developers assembled at FAO HQ and proceeded to create the generic software platform using an Agile Scrum methodology. By early 2012, the first release of Libre LAS was ready and pilot implementations began in Ghana, Nepal, and Samoa to validate and prove the Libre LAS concept. This case study tracks the initial development and implementation of Libre LAS in the pilot countries from 2011 to late 2012. It is presented from the standpoint of Brett, the Libre LAS Project Coordinator, and discusses organisational, cultural, stakeholder, and financial issues that conspired to derail the project. Ultimately, Brett is left to make some tough decisions around the pilot implementations to ensure the success of the overall project.