bluuebunny/crossref_metadata_2025 huggingface dataset:
Physics and chemical properties of the volcanic ash material adsorbed with the hexavalent chromium by x-ray absorption spectroscopy
Authors: Lontin Gristianho Lontin , Sendja Bridinette Thiodjio , Kamgne Duclair Tchana , Aquilanti Giuliana , Ben-Bolie Germain Hubert
Published: December 2022

X-ray absorption spectroscopy (XAS) was used to characterize the volcanic ash (VA) materials as a low-cost and natural environmental adsorbent for the sorption of Cr(VI). The batch adsorption method was employed to synthesize the sample of chromium(VI) sorbed by VA. The results showed that the Cr-VA material is in the chromium oxidation state(III) and can be described as a composition of Cr2O3 (47.9%), FeCr2O7 (45.2%), and Na2Cr2O7 (6.9%). The promotion of the 1s Cr core electron implies the electronic transitions 1𝑠→3𝑑(𝑡2𝑔) and 1𝑠→3𝑑(𝑒𝑔). The first and second shells in the Cr-VA material were coordinated to the oxygen and chromium atoms in a distorted geometrical arrangement. The adsorption mechanism was associated with the chemical reduction of Cr(VI) to Cr(III) via an ion-exchange process. The XAS technique significantly contributes to the characterization of environmental VA, which can be proposed as an economical and alternative adsorbent for the sorption of Cr from contaminated wastewater.
An intelligent diagnosis and treatment system for in-hospital cardiac arrest based on deep reinforcement learning in the Utstein style
Authors: Shao Yan , Yang Zhou , Chen Wei , Zhang Yingqi
Published: December 2022

Background: Both in-hospital and out-of-hospital cardiac arrest have several causes and complexities. Therefore, it is difficult to analyze and create targeted treatment plans for cardiac arrest. Moreover, even basic patient informationis insufficient or missing in many cases. To address these challenges, we developed an intelligent diagnosis and treatment system for cardiopulmonary resuscitation and restoration of spontaneous circulation to reasonably complete the diagnosis and treatment process and improve the success rate of treatment during in-hospital cardiac arrest.
Methods: Using 10 years of data from Utstein style in-hospital cardiac arrest registries in seven hospitals in China’s Hebei Province, we developed a two-stage intelligent diagnosis and treatment system based on the basic situation of different cases during cardiac arrest using deep reinforcement learning. This approach is aimed at maximizing the success rates of cardiopulmonary resuscitation and maintaining blood pressure at an optimal value during the restoration of spontaneous circulation. We employed Monte Carlo simulation to analyze the uncertainty.
Results: When comparing the actual diagnosis and treatment with those based on other models during cardiopulmonary resuscitation and restoration of spontaneous circulation in different conditions (sufficient and insufficient basic patient information), the average reward scores of the treatment plan provided by the intelligent diagnosis and treatment system developed in this study increased to 9.9–23 from 2.39.
Conclusions: The intelligent diagnosis and treatment system for in-hospital cardiac arrest based on deep reinforcement learning under the Utstein mode developed in this study can propose a reasonable diagnosis and treatment plan when in-hospital cardiac arrest occurs. Moreover, it can effectively induce cardiopulmonary resuscitation and restoration of spontaneous circulation processes in different patients even when basic patient informationis insufficient or missing.
Does repeated exposure to hydrogen peroxide induce Candida auris resistance?
Authors: Cobrado Luis , Ricardo Elisabete , Ramalho Patricia , Fernandes Angela Rita , Rodrigues Acacio Goncalves
Published: December 2022

Background
In order to minimize environmental colonization by microorganisms that may persist and thrive in healthcare settings, thus reducing healthcare-associated infections (HAIs), new insights over already known biocides are certainly of relevance. Although the efficacy of hydrogen peroxide (H2O2) against the emergent yeast Candida auris is moderately documented, concerns over the potential induction of resistance after repeated exposure do persist. The main objective of the present study was to evaluate the hypothetical induction of Candida auris resistance following 30 days of consecutive exposure to lethal and sublethal concentrations of H2O2. Furthermore, the authors aimed to elucidate about the rank of efficacy of H2O2 against C. auris comparing to other Candida species and whether different strains of C. auris may display different susceptibility to H2O2.
Methods
During the induction of resistance assays, both type strains and clinical isolates of Candida auris, Candida albicans and Candida parapsilosis were exposed repeatedly to defined concentrations of H2O2, for 30 days.
Results
After that period, no significant differences were found when comparing the minimal inhibitory concentration values of H2O2 in case of the induced strains versus each respective control. Moreover, H2O2 displayed similar effectiveness against all the tested Candida species and no differences were demonstrated among the distinct strains of C. auris.
Conclusions
The adoption of H2O2 solutions in routine protocols in order to promote disinfection standards against Candida auris, improving patient safety and reducing healthcare costs, is certainly welcomed.
Role of maturity status on the quality and volatile properties of mango fruits dried by infrared radiation
Authors: Li Dantong , Dai Taotao , Chen Mingshun , Liang Ruihong , Liu Wei , Liu Chengmei , Sun Jian , Chen Jun , Deng Lizhen
Published: December 2022

Drying characteristics and quality attributes are greatly dependent on the maturity status of fresh fruits. Hence, this work investigated the changes of quality and volatile properties of mangoes at different ripening stages (increased from RS-1 to RS-4) during infrared drying. Results showed that, the increases of hardness and total soluble solids/titratable acid during drying were varied with the ripening stage of fruits. Fruits at RS-3 obtained the highest increase in total phenolic (8.72 mg/g), the most dramatic decrease in vitamin C (5.58 mg/g), and the lowest decrease in β-carotenoid contents (56.49 mg/100g) during drying. After drying, the lower L* values, higher a* and b* values were obtained at products with higher ripeness, and the RS-2 and RS-3 achieved better color. Multivariate data analysis revealed that the aroma of dried mangoes had a clear distinction at different ripening stage, and the fruity aroma from RS-3 was the most intense. According to the comprehensive quality evaluation model, the qualities of dried mangoes were in the order: RS-3 > RS-4 > RS-2 > RS-1.
Longitudinal relationships among loneliness, social anxiety, self-esteem and self-concept in rural left-behind children: a cross-lagged study
Authors: Li Xiaolin , Zhou Zhenqian , Peng Dianhui , Lu Chunxia , Long jiayi , Xiong Yan , Dong Weixin
Published: December 2022

Background: Loneliness is one of the most common mental health problems among Rural Left-behind Children (RLBC) in China. Social anxiety, self-esteem and self-concept are primary correlates that are linked with loneliness, yet there is limited evidence of causal or temporal associations between these variables in RLBC. Therefore, this study explores the gender differences in RLBCs loneliness, social anxiety, self-esteem and self-concept, and aims to clarify the longitudinal cross-lagged relationship among the four.
Method: Using Children’s Loneliness Scale (CLS), Social Anxiety Scale for Children (SASC), Rosenberg’s Self-Esteem Scale (SES) and Piers-Harris Child Self-concept Scale (PHCSS) to assess the 812 RLBC. All assessments of CLS, SASC, SES, and PHCSS were measured in identical conditions at schools at the baseline (T1) and the end of the 1 year (T2). Descriptive statistics and Mann-Whitney U test were used for gender differences in variables. Partial correlation analysis of controlling gender was used to investigate the internal relationship of variables. A cross-lagged analysis were used to examine the longitudinal relationship between these variables.
Result: The result show that gender differences between CLS and SES were not statistically significant (P>0.05), but the gender difference between SASC and PHCSS was statistically significant (P<0.05). Additionally, both simultaneous and sequential correlations between CLS, SASC, SES and PHCSS were significant (all P<0.001). Lastly, CLS (β=0.491, P<0.001), SASC (β=0.229, P<0.01), SES (β=-0.140, P<0.05) and PHCSS (β=0.121, P<0.001) at T1 significantly predicted CLS at T2.
Conclusion: There were gender differences in social anxiety and self-concept of RLBC. Meanwhile, social anxiety, self-esteem and self-concept have unidirectional forecasting effect on loneliness.
Molecular pathological characteristics and tumour immune microenvironment of lung malignancies with RET rearrangement
Authors: Gao Qing-Yun , Xiao Fa-Man , Lin Xiao-cheng , Chen Yu-Qing , Li Yu-Fa , Lu Chang , Su Jun-Wei , Tan Quan-Quan , Zhang Chan-Yuan , Yang Jiao , Wu Yi-Long , Chen Hua-Jun , Yang Jin-Ji
Published: December 2022

Purpose
For patients with lung malignancies with RET rearrangement, the efficacy of immune checkpoint inhibitors is limited. The characteristics of the tumour immune microenvironment (TIME) and molecular pathological features of these patients have not been well elucidated.
Methods
The pathology and TIME characteristics of 29 patients with lung malignancies with RET rearrangement were retrospectively analysed, and their relationships with clinical efficacy and prognosis were investigated. Gene detection relied on high-throughput sequencing, and TIME detection was based on multiplex immunohistochemistry technology.
Results
Of the 29 patients, 86% (25/29) had adenocarcinoma, and the acinar type accounted for the greatest percentage of patients, followed by the solid type, regardless of whether the disease was early or locally advanced and metastatic. In addition, we report a novel KIF5B-RET(k24:R8) rearrangement in pulmonary sarcoma. The density of CD8 + T cells in the tumour stroma in the early-stage patients was significantly higher than that in the locally advanced and metastatic patients (P = 0.014). The proportion of M2 macrophages in the tumour stroma was significantly higher than that in the tumour parenchyma (P = 0.046). Although the difference was not statistically significant (P = 0.098), patients positive for M2 macrophage infiltration into the tumour parenchyma (≥ 5%) may have had a better prognosis.
Conclusions
A novel KIF5B-RET rearrangement variant in pulmonary sarcoma shows similar TIME characteristics to lung cancer. Among patients with lung malignancies with RET rearrangement, patients with M2 macrophage infiltration into the tumour parenchyma may have a better prognosis, but further studies with larger cohorts are needed.
More accurate detection and attribution by use of cointegrating vector time series models
Authors: Stephenson David Brian , Turasie Alemtsehai , Cummins Donald
Published: December 2022

Scaling factors in detection and attribution studies are typically estimated by performing a least squares regression of the observed trending variable, e.g. annual Global Mean Surface Temperature (GMST), on the equivalent variable simulated by a climate model.
This study proposes instead to obtain the scaling factors by dynamically modelling the time series as a cointegrating Vector Auto-Regressive (VAR) time series process. It is shown that a 2nd order cointegrating VAR(2) model is theoretically justified if the observed and simulated variables can be represented as a one-box AR(1) response to a common integrated forcing. The VAR(2) model can be expressed as a Vector Error-Correction Model (VECM) and then fitted to the data to obtain the cointegration relationship, the stationary linear combination of the two variables, from which the scaling factor is then easily obtained.
Estimates of the scaling factor from the VAR(2) model are critically compared to those from Ordinary Least Squares (OLS) and Total Least Squares (TLS) for GMST data simulated by a simple stochastic model of the carbon-climate system and for historical simulations from 16 climate models in the Coupled Model Intercomparison Project 5 (CMIP5) experiment. Results from the toy model simulations show that the slope estimates from OLS are negatively biased, TLS estimates are less biased but have high variance, and the VAR(2) estimates are unbiased and have lower variance and provide the most accurate estimates with smallest mean squared error. Similar behaviour is noted in the CMIP5 data. Hypothesis tests on the VAR(2) fits found strong evidence of a cointegrating relationship with the observations for all the CMIP5 simulations.
Tissue stretching is a confounding factor for the evaluation of neurodegeneration in the ever-growing killifish
Authors: Bergmans Steven , Serneels Pieter-Jan , Masin Luca , Moons Lieve
Published: December 2022

The fast-ageing killifish, Nothobranchius furzeri, has gained increasing attention as a promising gerontology model to study age-related processes and neurodegeneration. Interestingly, it is the first vertebrate model organism that shows physiological neurodegeneration at old age in its central nervous system (CNS), including its brain and retina. However, the fact that the killifish brain and retina are ever-growing tissues complicates studying neurodegenerative events. Indeed, recent studies showed that the method of tissue sampling, either using sections or whole-organs, has a large effect on the observed cell densities in the fast-growing CNS. In this study, we elaborated on how these two sampling methods alter neuronal frequency within the retina and how this tissue grows throughout life.
Analysis of cellular density across the different retinal layers in cryosections revealed age-dependent cell loss, that was not observed in retinal whole-mounts, as a result of an extremely fast retinal expansion with age. Using BrdU pulse-chase experiments, we were able to show that the young adult killifish retina mainly grows by cell addition, largely facilitated by the ciliary marginal zone. However, with increasing age, the neurogenic potency of this zone declines while the tissue keeps on growing. Further histological analyses revealed tissue stretching, including cell size increase, as the main driver of retinal growth in older fish. Indeed, both cell size and distance between retinal neurons augments with ageing, thereby decreasing neuronal density.
All in all, these findings highlight the need for tissue-wide counting methods to reliably quantify cell numbers in the fast-growing killifish.
Repair method for multiple adjacent small skin defects
Authors: Xiong Tingfeng , Ou Yangze , Guo Lei , Zhan Taiguo
Published: December 2022

Local skin flaps can be used to repair isolated defects in the skin. Numerous flap repair methods have been described, A single defect is very easy to repair, but it is not easy to repair when there are dense local defects. Guidance directing the repair of multiple adjacent skin defects is undescribed. Therefore, we propose the repair method. The adjacent skin flap is transferred and sutured on the basis of retaining all of the skin, and finally several J and W-shaped incisions can be formed. Concurrently, the complex multiple defects are stratified into simple single defect, double defect and triple defect categories. Hence this approach is termed the "JW" repair program. In this study, There were 13 patients in this group across 15 geographical locations. 4 patients were male and 9 female. Patient age ranged between 17 and 44 years old. The defect area after excision ranged from 0.3cm×0.3cm to 2.3cm×2.3cm. Defects were repaired using the "JW" repair program. 13 patients healed well, while one case suffered a small degree of skin necrosis at the tip of the flap, which was repaired. All patients achieved satisfactory appearance upon healing with no dog ear formation and no appearance deformation. The repair method therefore simplifies the complex repair of multiple adjacent skin defects and is a useful and easy-to-master technique. It can maximize the preservation of normal skin, reduce local tension, and thus reduce scarring.
Weighted asynchronous subdomain adaptation network for unsupervised fault diagnosis of bearing
Authors: Bo Lin , Sun Kong , Tang Zhi , Wei Daiping
Published: December 2022

The research of unsupervised cross-domain fault diagnosis for bearing is of great significance. However, there are still some problems to be solved. For example, a single predictor may not enough to acquire accurate pseudo-labels in target domain. In addition, global feature alignment may cause different subdomains of source and target domains to be too close. Finally, due to the inaccuracy of pseudo-labels, the effect of local subdomain feature alignment is also very limited. To this end, this paper proposes a weighted asynchronous subdomain adaptation network. First, according to the domain adaptation loss, a weighted integrated adaptation mechanism is constructed to get more accurate target pseudo-labels. Secondly, an asynchronous joint distribution alignment strategy is utilized to address the above mentioned problem caused by considering global alignment and local alignment separately. The proposed network is applied to perform various unsupervised cross-domain fault diagnosis tasks, and the experiment results indicate its superior diagnostic performance.
Migration and public finances in the EU*
Authors: Fiorio Carlo , Frattini Tommaso , Riganti Andrea , Christl Michael
Published: December 2022

We provide novel and comprehensive evidence on the net fiscal contributions of natives and migrants to the governmental budgets of EU countries. We account for income taxes and cash benefits, along with indirect taxes and in-kind benefits, which are often missing in standard datasets. We find that on average, migrants were net contributors to public finances over the period of 2014--2018 in the EU and, moreover, that they contribute approximately 1.5 thousand Euro more per capita each year than natives. We also show that this difference is partly due to the selection on characteristics that make migrants net fiscal contributors, such as demographic factors and employment probability.
Lower Rifampicin Plasma Levels are Associated with Poor Clinical Response in Abdominal Tuberculosis Patients
Authors: Ray Yogiraj , Kanswal Sunita , K Adarsh Aayilliath , Wig Naveet , Biswas Ashutosh , Ahuja Vineet , Velpandian Thirumurthy , Singh Urvashi B.
Published: December 2022

Purpose
The purpose of this study was to assess the Anti-tubercular treatment (ATT) levels and to determine the effect of pharmacokinetics/pharmacodynamics (Pk/Pd) of ATT on the treatment outcomes in patients with abdominal tuberculosis (ATB).
Methods
Serial measurements of ATT plasma levels were done in 45 patients with ATB at second week and at the end of first and second months of therapy. Liquid chromatography-tandem mass spectrometry was used to determine Isoniazid, Rifampicin, Pyrazinamide and Ethambutol levels in all blood samples.
Results
Low drug levels of Rifampicin was detected in 52 (38.5%) of 135 observations. Peak plasma Rifampicin level was found to be significantly lower at the end of the second month of treatment among poorly responding patients {p < 0.014 (C1hr) and 0.027(C4hr)}.
Conclusion
Low plasma levels of rifampicin were associated with a poor response to treatment in patients with ATB. Therapeutic drug monitoring can guide dose modification of ATT to achieve target concentrations in patients with ATB and facilitate optimal treatment outcomes.
Exploring the opportunities and limitations of large language models in biomedical sector
Authors: Albarqawi Ahmad
Published: December 2022

The development of large language models (LLMs) in recent years has shown several opportunities for improving the biomedical sector and processing unstructured electronic medical records. Despite the potential of these models, their application in the biomedical and clinical fields needs to comply with regulations and mitigate existing biases, unfactual information generation, and any potential privacy concerns. Successful implementations of LLMs need an understanding of their use cases and limitations for strategies to revolutionize the healthcare industry and operations. This research does an exhaustive assessment of the published biomedical and clinical language models to comprehend the current problems, explore the best methods for overcoming the constraints and get the models suitable for use in regulated conditions.
Tumor boundary instability induced by nutrient consumption and supply
Authors: Feng Yu , Tang Min , Xu Xiaoqian , Zhou Zhennan
Published: December 2022

We investigate the tumor boundary instability induced by nutrient consumption and supply based on a Hele-Shaw model. The model describes the geometric evolution of the tumor region and is derived from taking the incompressible limit of a cell density model, which leads to the pressure vanishing on the free boundary. We investigate the boundary behaviors under two different nutrient supply regimes, in vitro and in vivo, where in the former case the supply is adequate, and in the latter case the supply is deficient. Our main conclusion is that by investigating typical solutions of the tumor-nutrient model with the asymptotic analysis with respect to the domain perturbation, the tumor boundary in the in vitro regime is shown to be stable regardless of the nutrient consumption rate. However, boundary instability occurs when the nutrient consumption rate exceeds a certain threshold in the in vivo regime, and the bifurcation threshold has a monotonic dependence on the frequency of the domain perturbation.
Mathematics Subject Classification (2010). 35R35, 92C10, 70K50, 74G10
Transcriptome and Metabolome based candidate mechanism of BCR-ABL independent resistance to Olverembatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia
Authors: Yin Zhao , Liao Meiyan , Yan Rongrong , Li Guangchao , Ou Ruiming , Liu Zhi , Zhong Qi , Shen Huijuan , Zhu Yangmin , Xie Shuangfeng , Zhang Qing , Liu Shuang , Huang Jing
Published: December 2022

Olverembatinib represents the third-generation breakpoint cluster region protein-Abelson-murine leukemia 1 (BCR-ABL1) tyrosine kinase inhibitor (TKI) with oral bioavailability, which can be used to overcome the T315I mutation in Philadelphia chromosome-positive (Ph+) leukemia. BCR-ABL independent resistance to Olverembatinib has been reported among patients in various clinical cases. However, the mechanism of Olverembatinib resistance has rarely been reported. This study has illustrated bone marrow cell transcriptome and Metabolome profiles among Ph + acute lymphoblastic leukemias (ALL) cases pre- and post-Olverembatinib resistance. The transcriptome studies demonstrated that PI3K/AKT, purine metabolism, and other signaling pathways could play a vital role in Olverembatinib resistance. As suggested by metabolomics, Olverembatinib resistance in Ph + ALL was associated with purine metabolism alterations. Subsequently, High-Performance Liquid Chromatography (HPLC) along with Real-time Quantitative PCR (RT-qPCR) was utilized to measure purine metabolism-related mRNA levels and metabolism expression levels between Olverembatinib resistance and sensitive cell lines. Our results elucidate the mechanism of Olverembatinib resistance in Ph + ALL at transcriptome and metabolome levels, which facilitate a better understanding of Olverembatinib resistance and hence may prove crucial in identifying novel drugs to tackle this conundrum.
Mechanism of Galectin 8 protein in Aedes aegypti to survive Bt Cry11Aa
Authors: Hu Xiaohua , Huang Xianhui , Liu Jiannan , Zhao Guohui , Wu Songqing , Yu Xiaoqiang , Guan Xiong , Zhang Lingling
Published: December 2022

Aedes aegypti is a crucial vector of many diseases that cause millions of deaths worldwide. Cry11Aa display high toxicity to the larvae of Ae.aegypti. And the Galectins are a family of β-galactoside binding proteins that play a role in immune responses and may also affect Cry11Aa toxin activity. In our previous work, Galectin 6 and Galectin 14 were found to affect toxicity of Bt toxins. However, there are also some other galectin genes expressed in the gut of Ae.aegypti, such as Galectin 8, whose function is still not confirmed yet. In order to further understand its function and molecular mechanism, Ae.aegypti galectin 8 gene was cloned, expressed the recombinant protein and purified in this study. The bioassays results indicated that Galectin 8 is similar to Galectin 6 to reduce the toxicity of Cry11Aa. In order to determine interactions among Galectin8, Cry11Aa and toxin receptors, Octet Red System, Western blot, far-western blot assay were also performed. Octet Red System result showed that Galectin 8 could also bind to BBMVs of Ae.aegypti, but the kDa value is smaller than that of Galectin 6, indicating that Galectin 8 had a stronger binding ability to BBMVs than Galectin 6. Western blot and far-western blot analyses also demonstrated that Galectin 8 could bind to Ae.aegypti receptor ALP1 and APN2, similar to result of protein docking simulation. All of these results support the conclusion that Galectin 8 may increase block Cry11Aa from binding to ALP1 and APN2 than Galectin 6, which might decrease the toxicity of Cry11Aa for Ae.aegypti.
A Predator-Prey Model from Collective Dynamics and Self-Propelled Particles Approach
Authors: Yaya Yaya Youssouf
Published: December 2022

The definition and description of the dynamics of predator-prey system consists in one of the fundamental problems of the population biology. Since 1925, several models have been introduced. Although they are highly effective, most of them neglect certain relevant criteria such as the spatial and temporal distribution of the studied species. We introduced these criteria by coupling two models designed initially for collective dynamics. The first is for predators mobility, a Vicsek type model and the second is a Brownian Particle (BP) model for prey. We observed, as naturally in the classical models, periodic cycles of the density of predators and prey. In this case, the period of oscillations depends relatively on the collective dynamics parameters.
Simulation of the buffering process and carbon sink effect of karst soil on sulfuric acid rain in Guilin City, southwest China
Authors: Zhao Guangshuai , Huang Qibo , Zhu Yinian , Xu Yiling , Pu Zhenggong
Published: December 2022

After acid rain has settled onto the surface and has been buffered by karst soil, the capacity of acid rain to participate in carbonate rock erosion and its impact on the karst carbon sink are still unclear. To clarify the buffering process and karst carbon sink effect of karst soil with acid rain, experiments on leaching of sulfuric acid rain were conducted with pH 3.5, 4.5, and 6.5 with different karst soil thicknesses. Results have shown that the karst soil buffer to acid rain predominantly occurs in the surface soil layer. The loss of Ca2+ and Mg2+ due to acid rain H+ accounted for a small proportion of the Ca2+ and Mg2+ in the leached liquid. Soil water-soluble Ca2+, Mg2+, and soil exchangeable calcium and magnesium are the main Ca2+ and Mg2+ components in the leached liquid. They were exchanged by the H+ generated by the dissociation of soil CO2 dissolved in the soil water. A total of 74% of dissolved inorganic carbon (DIC) in the leached liquid came from soil CO2. Differences in the rainfall pH value had little effect on the sources of DIC in the leached liquid. In the karst soil area, the carbon migration process caused by rainfall is mainly dominated and driven by the soil carbon pool. Under strong acid (pH 3.5) precipitation conditions, the surface soil carbon sink was significantly higher than the deep soil carbon sink. Meanwhile, under weak acid (pH 4.5) precipitation conditions, the difference in soil carbon sink capacity of different soil thicknesses was relatively low. The capacity of the soil carbon sink had no pronounced relationship with soil depth.
Structure of plant Photosystem I in a native assembly state
Authors: Naschberger Andreas , Fadeeva Maria , Klaiman Daniel , Borovikova-Sheinker Anna , Caspy Ido , Nelson Nathan , Amunts Alexey
Published: December 2022

Plant Photosystem I (PSI) consists of at least 13 nuclear-encoded and four chloroplast-encoded protein subunits, acting as a sunlight-driven oxidoreductase. Here, we report the first structure of PSI assembly intermediate isolated from greening oat seedlings. The assembly state displays absence of at least eight subunits and lacks the photoreduction activity, which is attributed to an elimination of the plastocyanin (Pc) binding site, due to a missing subunit PsaF. The data shows that PsaF is a regulatory checkpoint that promotes the assembly, effectively coupling biogenesis to function.
Typhoid fever in a rare form caused by eating overripe pineapple: A Case Report and Literature Review
Authors: Bereda Gudisa
Published: December 2022

Typhoid fever is an acute infection caused by Salmonella typhi, especially when it is waterborne or foodborne. Overripe pineapple causes typhoid fever because overripe pineapple is a desirable host for the survival of Salmonella typhi. The importance of typhoid fever as a public health burden is reduced by early detection and appropriate antibiotic treatment. A 26-year-old black African male health care worker was admitted to the clinic on July 21, 2022, with a significant chief complaint of headache, loss of appetite, and watery diarrhea. The admitted patient presented with a two-day history of hyperthermia, headache, loss of appetite, and watery diarrhea, as well as back pain, joint weakness, and insomnia. The H antigen titer was positive, which was 1: 189 greater than the normal range and showed the past history of Salmonella typhi infection. The O antigen titer value detected was a false negative result because it was done before the 7-day onset of fever. On admission, ciprofloxacillin 500 mg was given orally twice a day for seven days to treat typhoid by inhibiting the deoxyribonucleic acid replication of Salmonella typhi by preventing Salmonella typhi deoxyribonucleic acid topoisomerase and deoxyribonucleic acid gyrase. Typhoid fever pathogenesis is based on pathogenic factors, infecting species, and host immunity. By using the agglutination biochemical test, the Widal test was able to identify the patient's bloodstream as carrying the salmonella typhi bacteria that causes typhoid fever. Due to contaminated food or unsafe drinking water sources, typhoid fever is associated with travel to developing nations.
Secrecy Performance, RF/FSO Communication,Variable Gain Relaying, α − η − μ Fading Channel,M ́alaga Fading Distribution
Authors: Mandira N. S. , Kundu M. K. , Islam S. H. , Badrudduza A. S. M. , Ansari I. S.
Published: December 2022

With the completion of the standardization of fifth-generation (5G) networks, the researchers have begun visioning sixth-generation (6G) networks that are predicted to be human-centric. Hence, similar to 5G networks, besides high data rates, providing secrecy and privacy will be the center of attention by the wireless research community. To support the visions beyond 5G (B5G) and 6G, in this paper we propose a secure radio frequency (RF)-free space optical (FSO) mixed framework under the attempt of wiretapping by an eavesdropper at the RF hop. We assume the RF links undergo α − η − µ fading whereas the FSO link exhibits a unified Málaga turbulence model with pointing error. The secrecy performance is evaluated by deducing expressions for three secrecy metrics i.e. average secrecy capacity, secure outage probability, and probability of non-zero secrecy capacity in terms of univariate and bivariate Meijer’s G and Fox’s H functions. We further capitalize on these expressions to demonstrate the impacts of fading, atmospheric turbulence, and pointing errors and show a comparison between two detection techniques (i.e. heterodyne detection (HD) and intensity modulation with direct detection (IM/DD)) that N. S. Mandira et al. clearly reveals better secrecy can be achieved with HD technique relative to the IM/DD method. The inclusion of generalized fading models at the RF and FSO hops offers the unification of several classical scenarios as special cases thereby exhibiting a more generic nature relative to the existing literature. Finally , all the analytical results are corroborated via Monte-Carlo simulations.
B2B Communication Strategy: Introducing a New Multifunctional Application for the Waste Management Industry
Authors: Svetlik Jaroslav , Lastuvka Igor
Published: December 2022

This empirical study aims to present a real case study in the form of drafting an effective communication strategy to implement the new digital waste management application, SOWA, for B2B customers. In the Czech Republic (and elsewhere) businesses still do not accept that if they do not start working systematically with their waste, they will not have anything to produce in the future. They will not have space for their production and priority business areas. Moreover, in the rules of the new green policy, this area would become more expensive soon. However, the management of companies does not often realize the importance of innovations in this area of social, economic, and environmental reality. To effectively appeal to businesses often fighting to survive only by their social responsibility may not be a sufficiently strong argument in the current climate. At the same time, companies engaging in waste management solve the problem of how to improve their competitiveness, strengthening their position in this very competitive market. These companies thus face a major decision to introduce new digital technologies and their applications and to persuade the customers in the B2B market that these innovations represent maximum time savings and automated service for their businesses. Therefore, these companies ask themselves which marketing communication tools to use and which target groups will effectively convince them that the digitization project would benefit them. In terms of communication, the B2B market has several specifics alongside it compared to a larger, more widespread B2C market in marketing communication theory. These differences are essential in terms of the effectiveness of addressing recipients. The new communication strategy’s draft rests on the authors’ research, which mostly concerns the different target groups of B2B customers. The literature review characterizes the state of current knowledge of the issue of modern waste management and the necessary theoretical base in the specific field of B2B communication. This paper provides the necessary data and information which form the starting point of the communication strategy for one of the fundamental innovations in the field of waste management regarding the introduction and rollout of the new multifunctional application in the Czech Republic. Further rollout of this innovation to other central European countries is considered and subject to serious reflection.
Conference Workshop Proceedings: Developing a Scholarship of Teaching and Learning Portfolio in Applied Horticulture
Authors: Miller Chad T. , Harkess Richard L. , Haynes Cindy L. , Williams Kimberly A. , Wright Amy N.
Published: December 2022

Preparing faculty to conduct quality teaching is critical to maximize student learning and the educational experience. As increased attention to faculty effectiveness and effect of their teaching program is observed, the more important it becomes for faculty to engage in the scholarship of teaching and learning (SoTL). The workshop “Developing a scholarship of teaching and learning portfolio in applied horticulture” was conducted at the 2022 American Society for Horticultural Science conference in Chicago, IL, USA, and featured a panel of teaching scholars who provided insight and guidance for developing, enhancing, evaluating, and promoting SoTL for both traditional classroom teachers and extension educators.
EMPIRICAL STUDY: THE ASSESSMENT OF FINANCIAL STATEMENTS IN INDONESIA ISLAMIC BANK BASED ON IFRS AND AAOIFI STANDARD
Authors: Nisa Fauzatul Laily , Rahmawati Lilik
Published: December 2022

Abstract: This study aims to measure how far Indonesian Islamic banking adopts AAOIFI and IFRS standards in its financial reporting. This study uses the annual report of Indonesian Islamic banks in the period 2014-2018 obtained from 5 Islamic banks in Indonesia compiled from the official website of the five banks that were sampled. This research uses a quantitative approach by using a Content Analysis method. This study's results indicate that Indonesian Islamic banking is more inclined to adopt IFRS standards in its annual financial reports (annual report). It can be proven by the large number of percentages of Islamic banking that predominantly meet the total items selected as IFRS standards in its financial statements, compared to the percentage Islamic banking that matches the total items selected as AAOIFI standards.

 

Keywords: financial statements; Islamic banks; IFRS; AAOIFI
İTİRAZIN İPTALİ DAVASININ TÜRK MİLLETLERARASI USUL HUKUKU YÖNÜNDEN DEĞERLENDİRİLMESİ
Authors: KONYALI Sinan Can
Published: December 2022

İtirazın iptali davasının kendisine özgü niteliği Türk icra hukukunda birçok sorunu ve tartışmayı beraberinde getirmektedir. Söz konusu tartışmaların milletlerarası usul hukuku boyutuyla da ele alınması gerekmektedir. Keza yabancılık unsuru barındıran özel hukuk ilişkilerinde taraflar, giderek artan bir biçimde yetki ya da tahkim anlaşmaları akdetmekte ve uyuşmazlığın yabancı devlet mahkemesi ya da hakemler önünde görülmesi konusunda anlaşabilmektedir. Aralarında yetki ya da tahkim anlaşması bulunması durumunda alacaklının, borçluyla aralarındaki güven ilişkisi gereği uyuşmazlığın çözümü için yetkili yabancı mahkemeye ya da hakemlere başvurması beklenir. Ancak alacaklı yetki ya da tahkim anlaşmasının varlığına rağmen borçlu aleyhine ilamsız icra takibine başvurabilmektedir. Borçlunun takibe itiraz etmesi durumunda ise itirazın kaldırılması yoluna başvuramayan alacaklı tarafından takibe devam edilebilmesinin tek yolu itirazın iptali davası ikame etmektir. İtirazın iptali davası konusunda Türk mahkemelerinin yetkisi münhasır değildir. Dava her ne kadar icra hukuku içerisinde yer alsa da maddi hukuk karakteri gereği tarafların yetki anlaşmalarının geçerliliğine engel olmaması lazım gelir. Tahkim bakımından ise para veya teminat borçlarını içeren itirazın iptali davasının konu yönünden tahkime elverişli olarak kabul edilmesi gerektiği ve hakemlerin itirazın iptaline karar verme konusunda yetkili oldukları son yıllardaki Yargıtay kararları ve doktrin görüşleri ışığında ortaya konmuştur. İtirazın iptali davası, yalnızca Türk ve İsviçre Hukuku’nda kabul edilmektedir. Dolayısıyla yabancı hâkimin ya da hakemlerin davayı ne şekilde vasıflandıracağı, esasa uygulanacak hukuku ne şekilde belirleyeceği gibi birçok problemle karşılaşılmaktadır. Bunun yanı sıra bir yıllık hak düşürücü sürenin yabancı mahkemeler ya da hakemler önünde açılan davalar üzerindeki etkisi, tazminatlar, yabancı mahkeme ya da hakem kararına binaen ilamsız icra takibi başlatılıp başlatılamayacağı konuları tartışılması gereken sorunlardan birkaçıdır.
ACENTENİN DENKLEŞTİRME İSTEMİ HAKKINDAKİ YARGI KARARLARINA İLİŞKİN BAZI DEĞERLENDİRMELER
Authors: YILDIZ Burçak
Published: December 2022

Denkleştirme istemine ilişkin Türk Ticaret Kanunu (TTK) m. 122 hükmüne, Avrupa Birliği’nin 86/653 sayılı Yönergesi mehaz teşkil etmektedir. Bu nedenle Avrupa Birliği Adalet Divanı’nın (ABAD) anılan Yönerge’ye ilişkin kararları, hukukumuz için de önem taşımaktadır. Çalışmamızda ABAD ve Türk yargı kararlarının denkleştirme istemine ilişkin bakış açısı değerlendirilmektedir. Denkleştirme istemine ilişkin Yargıtay kararlarında en sık rastlanan bozma sebebi: tarafların kendilerine düşen ispat yüklerini yerine getirmemiş olmalarına rağmen ilk derece mahkemelerinin talebi kabul etmiş olmalarıdır. TTK m.122.1’de sayılan üç unsurun ilk ikisinin varlığını davacı acente ispatlamalıdır. TTK m.122.1.c hükmünde sözü edilen üçüncü unsura göre: denkleştirme istemi ancak “hakkaniyet gerektirdiği takdirde ve oranda” talep edilebilmektedir. Ancak söz konusu unsur, kural olarak sağlanmış kabul edilmektedir. Anılan hususa aykırılık bulunduğu iddiasında olan davalı, bu iddiasını ispatlamakla yükümlüdür. Yargıtay, davalının bu iddiasını ispatlarken kullanabileceği kıstasları belirlemiştir. ABAD, denkleştirme istemi için varlığı ispatlanması gereken “yeni müşteri” kavramının içeriğini yorumlamıştır. Divan yenilikten kastın müşterinin müvekkil ile ilk kez sözleşme akdediyor olması değil, müşterinin söz konusu ürünleri ilk kez satın alması olduğunu ifade etmiştir. ABAD, müvekkilin acenteye müşteri listesi vermiş olmasının bu listedekilerin yeni müşteri sayılmasını engellemeyeceğine hükmetmiştir. Denkleştirme istemine engel olan sona erme sebepleri, istisnai nitelik taşımakta olup; bunların dar yorumlanması gerekmektedir. ABAD, deneme süresi içinde sona ermiş acentelik sözleşmelerinde de denkleştirme istenebileceğini kabul etmiştir. Divan, ayrıca, müvekkil sözleşmeyi feshi ihbar süresi tanıyarak sona erdirdikten sonra acentenin sözleşmeyi ihlal eden davranışlar gerçekleştirmiş olmasının, denkleştirme isteminden kaçınma yetkisi tanımadığına hükmetmiştir.
Influence of light and color of advertising photography on consumers’ purchase intention
Authors: Chen Fenglei , Sukpasjaroen Khunanan , Chankoson Thitinan
Published: December 2022

With the rapid progress of information technology, short video advertising has flourished, and the performance of advertising images can stimulate consumers’ purchase behavior through short video platforms. Drawing on stimulus-organization-response (S-O-R) theory, this study explored the moderating role of short video platforms on the relationship between light and color of advertising photography and brand image and the mediating role of brand image between light and color and consumers’ purchase intention. The data were collected using a questionnaire focusing on consumers who purchased detergent products in major supermarkets in East China. The survey covered 200 respondents from different industries, genders, and education levels in various provinces and cities in East China. Collected data were analyzed using regression analysis. It was found that the light and color of advertising photography have a facilitating effect on consumers’ purchase intention. Furthermore, brand image mediates the relationship between light and color and consumers’ purchase intention. Finally, short video platforms can moderate the relationship between light and color and brand image. This study will encourage scholars to use the S-O-R model in academic research to investigate how advertising affects consumers’ purchase intention and guide companies to use short video platforms to advertise and increase product sales.
AcknowledgmentThis paper is part of the Doctor of Philosophy Program in Management, Chakrabongse Bhuvanarth International Institute for Interdisciplinary Studies (CBIS), Rajamangala University of Technology Tawan-OK, Thailand. The researchers would like to thank all cited experts that contributed to this study.
Functions and principles of organization of the Ukrainian Armed Forces
Authors: С. Ю. Поляков
Published: December 2022

This article analyzes the functions and principles of the law that underlie the ensure of organization and functioning of the Ukrainian Armed Forces. It was suggested the author’s definition of the Armed Forces of Ukraine functions. And it was presented the general description of the principles of Armed Forces of Ukraine’s activity.
Establishment and development perspectives of judges’ self-government in Ukraine
Authors: О. О. Овсяннікова
Published: December 2022

The article studies the creation history of judges’ self-government institute in Ukraine, its primary forms are reviewed. The legislature in  creation and functioning of the judges’ self-government bodies of foreign countries is analyzed. Propositions as to  development perspectives of judges’ self-government bodies in Ukraine are given.
The standards of the prisoner’s rights restrictions in the practice of the european court of human rights
Authors: В. О. Човган
Published: December 2022

The article is dedicated to the research of the standards of prisoner’s rights restrictions. In this context the question of the relevant practice of European court of human rights is analyzed.
Features and functions legitimacy context functioning of the judiciary
Authors: С. В. Гладій
Published: December 2022

The article by summarizing developments sociology, philosophy, political science, kratolohiyi legitimacy of the essence, defines its characteristics and functions. Evaluated the use of this knowledge when disclosing the nature of judicial legitimacy.
The problem of defining the subject of a criminal assault in the area of drug trafficking
Authors: Ю. М. Ігнатенко
Published: December 2022

The article deals with problems of defining the subject of a criminal assault in illicit drugs, called attention to the criteria and reasons for inclusion of certain substances to the number of drugs.
SYSTEM OF COOPERATION BETWEEN STATE BODIES, LOCAL GOVERNMENT AND PUBLIC ORGANIZATIONS IN MODERN POLAND
Authors: Lesnyak Vitaliy
Published: December 2022

The article analyzes the system of cooperation between state bodies, local government and public organizations in Poland. During investigation activity we came to the conclusion that the basic legal instrument of cooperation forms between the state administration and non-governmental organizations is the Act of Law on Public Benefit and Volunteer Work. These mechanisms define interaction practice and legal framework for subsidies in the whole range of performance from public activities to the civil society organizations.
INTERNATIONAL INTEGRATION: THE EUROPEAN CONTEXT
Authors: Polishchuk Ihor , Vilkhivskyi Vladyslav
Published: December 2022

The article examines the general theory and European practice of international integration. The modern context of the European integration of Ukraine is revealed. It is noted that the full-scale military aggression of the Russian Federation against Ukraine in 2022 makes the process of European integration of the Ukrainian state irreversible. Putin's autocratic fascist regime, established in Russia, is attacking the young Ukrainian democracy, due to which a bloody dividing line is emerging between European civilization (Ukraine plays the role of an outpost) and Eurasianism (current territories of the Russian Federation). International integration is a world-historical, world unifying, objective historical process. The object of this process is human society. The elements of the integration complex are the subjects of interstate relations - national states. Integration has several levels of its development. The main importance is the interaction at the level of enterprises and organizations - direct producers of goods and services. It is here that integration ties arise in the main spheres of reproduction, structural restructuring of national economies is carried out, which leads to their mutual complementation and interweaving. It is concluded that the European Union represents one of the most successful and grandiose projects of long-term international integration in recent human history. This project will be completed only when Ukraine joins it as a full member, which defends European civilizational values with arms in hand in a fierce battle with Eurasian Russian barbarians.
ORGANISING THE ETHICS PROCESS IN THE ORGAN OF LEGISLATIVE POWER: THE US EXPERIENCE
Authors: Fabryka Alla
Published: December 2022

The search for ways to optimize the process of ethical regulation in the Ukrainian parliament necessitates the study of the experience of organizing such a process in a complex environment of legislators and politicians in other countries. The article is devoted to the analysis of the stages of formation of the process of ethical regulation in the US legislature, its ideological basis, structural elements, problems of functioning and ways to solve them.