bluuebunny/crossref_metadata_2025 huggingface dataset:
VIOLÊNCIA DOMÉSTICA CONTRA A MULHER NEGRA
Authors:   Adriano Dos Santos Oliveira, Oliveira Alan Wilha Viana de , Ataíde Jean Victor Gabino , Ferreira Maria Francisca da Silva , Souza Paulo Ricardo Fabá de , Silveira Sorayla Barbosa ,   Cleise Maria De Goes Martins
Published: November 2024

Violence is a practice that takes various forms and manifests in different contexts, directly impacting the physical and mental health of the victims. In the domestic context, it involves a range of abuses, whether physical, psychological, sexual, economic, or moral, perpetrated within the family environment. Structural racism legitimizes the perpetuation of these stereotypes, relegating Black women to subordinate roles, with limited social mobility and opportunities (Medeiros; Machado, 2020). This is an integrative literature review. For this study, scientific articles available from the Scientific Electronic Library Online (SCIELO), Latin American Literature in Health Sciences (LILACS), and the Virtual Health Library (BVS) were used. Domestic violence against Black women is a complex and multifaceted issue, deeply rooted in historical and sociocultural factors. To address this issue, it is crucial to implement inclusive public policies and promote education and awareness programs that address the specific needs of Black women. Collaboration between different sectors and communities is essential to create an effective and accessible support network.
ALTERAÇÕES NO PERFIL DOS MICRORGANISMOS CAUSADORES DE INFECÇÕES DO TRATO URINÁRIO DE IDOSOS, RESIDENTES NO MUNICÍPIO DE MARECHAL CÂNDIDO RONDON-PR, NO PERÍODO PRÉ E PÓS PANDEMIA DA COVID-19
Authors: Drehmer Gabriela Karling , Piaz Isabella dos Santos , Lazaretti Waleska , Ceglarek Vanessa Marieli
Published: November 2024

Urinary tract infections (UTIs) are frequent anomalies that affect the lower and upper urinary tract, in both sexes and all ages. Such infections are normally caused by gram-negative enterobacteria, which interfere with individuals' quality of life. This work aims to analyze how the Covid-19 pandemic influenced the profile and antimicrobial sensitivity of pathogens that cause UTIs in the elderly in the city of Marechal Cândido Rondon-PR, by verifying the results of positive urine cultures of elderly outpatients and hospitalized patients in the periods of May-December 2019 and May-December 2023. It is expected to find, as a result of the research, a difference in antimicrobial resistance and the predominant pathogen profile, bringing relevant information to be studied for the society of Marechal Cândido Rondon.
PREVALÊNCIA E PERFIL DE RESISTÊNCIA BACTERIANA EM RECÉM-NASCIDOS NA UTI NEONATAL: UMA REVISÃO DE LITERATURA
Authors: Baseggio Itauana Regina , Lazaretti Waleska
Published: November 2024

Healthcare-associated infections (HAIs) are a significant challenge in neonatal intensive care units (NICUs), primarily affecting newborns due to their immature immunity. The aim of this study was to analyze the prevalence and bacterial resistance profile in newborns admitted to the NICU, based on a literature review. The research followed an exploratory-descriptive design with a qualitative approach, and data were obtained from articles published between 2019 and 2024 in the Google Scholar, SciELO, and PubMed databases. The search was structured with keywords such as "prevalence of bacterial resistance," "neonatal ICU," "hospital infection," and "bacterial resistance profile," covering articles available in both Portuguese and English. The results showed that the most prevalent bacteria in the NICU include Pantoea agglomerans, Acinetobacter baumannii, Pseudomonas aeruginosa, Candida parapsilosis, MR (methicillin-resistant) bacteria, Escherichia coli, Staphylococcus sp., Klebsiella sp., and coagulase-negative Staphylococcus. The studies highlighted the complexity of bacterial infections, the diversity of pathogens, and the need for early diagnosis to ensure effective treatment. Antimicrobial resistance, especially among Gram-negative bacteria and coagulase-negative staphylococci, remains an ongoing challenge, requiring stringent prevention and monitoring strategies. Therefore, monitoring the microbiological profile in neonatal ICUs is essential to improve prevention and treatment strategies, reducing infection rates and antimicrobial resistance. The evidence underscores the importance of early interventions and targeted therapies to control these infections in vulnerable neonates.
A RELAÇÃO DA DOENÇA PERIODONTAL COM A ENDOCARDITE BACTERIANA: REVISÃO DE LITERATURA.
Authors: Barcelos Rogério Kalleby , Fagundes Daniele Paraguassu
Published: November 2024

Introduction: Patients at risk of developing bacterial endocarditis should be treated with prophylactic measures, such as antibiotic prophylaxis, treatment of endodontic and periodontal infections, and oral health maintenance, to reduce the possibility of bacterial endocarditis. Objective: To understand how a high-risk patient with periodontal disease can develop bacterial endocarditis, and how we can prevent it with prophylactic measures. Method: This research is characterized by being a systematic literature review carried out through bibliographical research, covering scientific articles and relevant documents that address the topic of antibiotic prophylaxis in patients with periodontal disease at risk of progressing to bacterial endocarditis. Results: Seven articles where selected, because they were adequate to the inclusion criteria and allowed to answer the objetctives of this study. Discussion: To reduce the incidence of infection, the prophylactic recommendation for bacterial endocarditis is the prescription of amoxicillin 2g, orally, one hour before the dental procedure. Conclusion: The dental surgeon must present knowledge about the management of a patient at risk of developing bacterial endocarditis. Antibiotic prophylaxis for bacterial endocarditis is the prescription of amoxicillin 2g orally one hour before the procedure.
CUIDADOS DE ENFERMAGEM EM PACIENTES COM INTOXICAÇÃO EXOGENA: UMA ANÁLISE DA ABORDAGEM NA EMERGÊNCIA
Authors: Sousa Amine Cristina Nogueira de , Pádua Vanessa da Silva , Júnior Silas de Souza
Published: November 2024

This article focuses on the analysis of nursing practices in cases of exogenous intoxication, with a focus on suicide attempts. The objective is to investigate how nursing interventions can contribute to the prevention of suicide due to exogenous intoxication and its influence on the quality of care provided to patients in a hospital environment. The methodology chosen was a literature review in which it went through some steps that will contribute to the theoretical basis through data analysis and information on the subject. In this way, 20 articles published from 2005 to 2024 were chosen through the Scielo, google scholar, virtual health library websites, and data were collected through the Tabnet system, DataSUS, which provides epidemiological data on exogenous intoxication, and suicide attempts related to this problem. With this, one of the ways to prevent exogenous intoxication and also suicide is through education and information: the nurse is one of the professionals The nurse is one of the nursing professionals with the competence to share information about the consequences of suicide attempts in an exogenous way, treatment, medication, and management strategy. This knowledge can enable the patient, thus helping to reduce depressive symptoms and even preventing suicide.
HISTÓRIA E MEMÓRIA DA COLÔNIA ALEXANDRA: UMA PROPOSTA DE EDUCAÇÃO PATRIMONIAL PARA O LITORAL DO PARANÁ
Authors: Nunes Juliana Gomes , Cintra Erica Piovam de Ulhôa
Published: November 2024

O presente artigo de pesquisa em história da educação, vinculado ao Grupo de Estudos e Pesquisas Histedice, procura debruçar-se sobre a vicejante história da Colônia Alessandra, hoje bairro Alexandra de Paranaguá e apresentar uma proposta de educação patrimonial que coopere para a construção da memória e manutenção da história desse patrimônio cultural um tanto obliterado do litoral do Paraná. São poucos os que conhecem a importância da “Colônia Alessandra” antes da ligação rodoviária da capital com o porto de Paranaguá. História desconhecida até mesmo para os que moram em Paranaguá, a 15 km de distância. Compreender essa história, bem como o potencial turístico que ali existe, como região de acesso, em solo, aos município de Morretes e de Antonina, e pelo mar, via presença do antigo “Portinho”, ao conjunto aquífero da região, e mesmo, reconhecer outras expressões culturais locais ali ainda existentes, como a Estação Ferroviária marco central do vilarejo, é o esforço da presente investigação que vislumbra a defesa de um projeto de educação patrimonial para o litoral paranaense. Para isso, investimos em uma ampla pesquisa sob referenciais bibliográficos diversos, fotos antigas, reportagens de jornais, arquivos digitais de acervos particulares e memórias de habitantes para montar essa peculiar história e os caminhos possíveis de torná-la ponto histórico, turístico e de permanente educação da memória de um povo e lugar. Nesse sentido, o presente texto encontra-se assim encaminhado: na primeira parte, trata de um breve histórico da origem da Colônia Alessandra, depois Alexandra; na segunda parte, os desafio educativos de Alexandra; e, na terceira parte, a proposta de educação patrimonial de Alexandra para o litoral paranaense.
A STUDY ON CRYPTO CURRENCY AS DIGITAL REVOLUTION - PROS AND CONS WITH SPECIAL REFERENCE ON INDIAN CONTEXT
Authors: Mrs. Shadiya M. S.  , Dr. S. Chitra
Published: November 2024

Crypto currencies are a new paradigm for money, that is a by-product of digital era. Digital currency or virtual currency supported by cryptography technologies are known as crypto currency. Crypto currency is typically decentralised digital cash intended for internet use. A crypto currency is a chain of encrypted data used to represent a unit of money. A digital currency or crypto currency, is an alternative payment method developed utilising encryption methods. Bitcoin and other digital currencies are held by millions of people as part of their financial portfolios. The main objective of this study is to enlist the key characteristics of crypto currencies, along with their merits and demerits. This paper's descriptive and explanatory analysis gathers the collective knowledge from recent studies and pertinent literature.
On construing a disorder: An unusual case of borderline
Authors: Dimčović Nada
Published: November 2024

A young man came to psychotherapy, claiming that he had Borderline Personality Disorder. The problem was his lifelong emotional reaction to rejection. As a child he was diagnosed as having enuresis, encopresis, ADHD and depression. When well, he acted as an able person who had worked in many capacities. Did he really suffer from BPD? Was he now, at the age of 35, acting as ‘borderline’, as ‘normal’, or both? We investigated his many roles comprising his dominant narrative, and tried to find out ways for him to break the cycle.
Valutazione delle percezioni dell’architettura neo-tradizionale di Di Fausto attraverso la metodologia dei costrutti personali
Authors: Agiel Ahmed , Lang Jon , Caputi Peter
Published: November 2024

Currently there is a major debate in architectural circles between two groups of scholars and professionals. One group completely rejects learning from and drawing on past architectures in creating new works while the other one builds a new architecture based on the past. Using personal construct methodology, this study examines the work of Di Fausto, as expressed in three Libyan designs of the 1930s. Results showed that a different architectural ‘brand image’ and an ‘ideal image’ exist in each culturally different region. Architectural design both as it taught and in practice must change towards incorporating the ‘inherent image’ of the local inhabitants in the creative thinking process of new buildings if those buildings are to be meaningful for them.
The Impact of Digital Currency on Global Trade : A New Frontier in International Accounting
Authors: Selvi Octapia Simatupang  , Febry Valentin Zebua
Published: November 2024

The rise of digital currencies such as Bitcoin and Ethereum has reshaped the landscape of global trade and financial transactions. This study investigates how digital currencies are influencing international accounting practices, focusing on the challenges and opportunities posed by this disruptive technology. By analyzing case studies from major economies, the paper explores the potential for blockchain to enhance transparency, streamline cross-border payments, and ensure better tax compliance. The findings suggest that while digital currencies provide efficiency gains, they also introduce regulatory and volatility risks that must be managed by accounting professionals globally.
The Role of Joint Auditing in Improving the Quality Characteristics of Accounting Information
Authors: Hayder Mohammed Ali Yousif
Published: November 2024

The study intends to define the idea of joint auditing, its significance and goals, and the allocation of audit responsibilities from the start of the audit process to the joint report's writing. It also seeks to elucidate the function of joint auditing in enhancing the caliber of the attributes of accounting data, which helps to provide high-quality information that benefits management and the beneficiaries of that information to make sound decisions that benefit the development of the institution's work for management and owners on the one hand and benefit investors on the other hand, as the study sample included a group of auditors In Iraq by creating and designing a questionnaire form and presenting it to a panel of arbitrators; data analysis was conducted using the statistical analysis software SPSS; and the findings were examined, an important role was reached for joint auditing in improving accounting information and the study recommended the need to adopt this type of audit method that increases users' confidence in accounting information.
The Role of Accounting Information Technology in Reducing Tax Evasion: an Applied Study on a Sample of Employees of Tax Departments in Middle AL -Furat AL –Awsat
Authors: Ali Sahib Noor
Published: November 2024

The current research aims to measure the role of accounting information technology represented by (Perceived benefit, ease of use) in reducing tax evasion represented by (Fair distribution of tax burden, penalties and penalties, combating tax evasion, employees efficiency, economic conditions) among a sample of employees of tax departments in the Middle Euphrates region, the research has stood on an important problem, which was formulated under the question of the research (What is the role of accounting information technology in reducing tax evasion?),  In order to address the problem, two hypotheses were formulated, and the research relied on the descriptive analytical approach in measuring, describing and analyzing the research variables, and the research relied on the questionnaire tool in collecting the necessary data, As (150) questionnaires were distributed to the concerned tax department employees, and (137) questionnaires were retrieved, with (129) questionnaires valid for analysis and (8) damaged questionnaires. To analyze the results, the (SPSS&AMOS) package was used (V.28). The research summarized several findings, foremost of which was that accounting information technology has an impact in reducing tax evasion. Additionally, there is a high degree of use of accounting information technology in improving the capabilities of tax department employees in the Middle Euphrates region to reduce tax evasion. The research recommends the use of modern accounting information methods and techniques to combat tax evasion and ensure timely payment of taxes in the right place.
TRANSFORMASI DIGITAL KEDAI KOPI SUDUT KOTA BERBASIS WEBSITE DENGAN JAVASCRIPT
Authors: Chandra David , Hermansyah Hermansyah
Published: November 2024

KOPI SUDUT KOTA merupakan salah satu produk kopi yang bergerak dibidang dagang milik perorangan. Toko kopi yang bertempat di daerah Jakarta Utara ini masih terbilang baru dalam bisnis dagang dibidang kopi. Dalam melakukan pemasaran kopi ini, pemilik masih menggunakan sistem yang dirasa masih kurang efektif untuk mengenalkan kopi kemasan miliknya, yaitu dengan cara menyebarkan brosur, promosi rumah satu ke rumah yang lain, promosi via group whatsapp, facebook, dan media sosial lainya. Aplikasi ini dibuat menggunakan modeling diagram  Unified Modeling Language (UML) sedangkan bahasa pemrograman Javascript dan Hypertext Preprocessor (PHP) dan Midtrans sebagai Admin Dashboard Payment Gatway. Metode pengumpulan data yang digunakan dalam penelitian ini yaitu metode wawancara, observasi, dokumentasi dan studi pustaka. dengan metode Waterfall. Dengan dibangunnya sistem ini diharapkan dapat memudahkan pegawai Kedai kopi Sudut Kota dalam mencari informasi, melakukan proses melihat menu apasaja yang ada di kedai Kopi Sudut Kota, Memesan Produk hingga Melakukan Pembayaran dengan macam” metode pembayaran.
В небето на войната
Authors: Nedialkov Dimitar
Published: November 2024

The author supports the idea that war is the permanent state of the world. New technological achievements have always played an active role in the final result of military efforts. Such a statement is extremely valid in the construction of the military systems operating in the air space. They are increasingly becoming robotic and engaging artificial intellect. For them to be managed to achieve the ultimate objectives of any air war, however, the key factor remains the human.
Неопределеност vs. сигурност
Authors: Atanasov Plamen
Published: November 2024

Uncertainty and security are explored in light of the tandem of negation-negated. Uncertainties are considered as inherently present in human activity and as aimed at security. It is shown that such activity is deliberately pointed at the notable changes happening in the world, and that resolving it is dependent on the knowledge with which human systems operate. Employed are derivatives of Goedel’s theorems and of the entropy of the grand scheme of information orderliness.
Финансиране на „Ислямска държава“ като секюритизиран проблем
Authors: Yordanova Gergana
Published: November 2024

“Islamic State” financing is global security`s securitized problem whose de-securitization is still on the agenda of a large number of researchers, experts of practice and criminologists. The present article systematizes and supplements the main sources of income according to the last FATF` classification, and represents the author's views on how terrorist financing could be minimized.
Molecular construction and recombinant expression in Escherichia coli of the protein coding for porcine somatotropin
Authors: Hernanez Ramirez Janet , Morales Arrieta Sandra , Cano Buendía Jose Alberto , González Lozano Miguel
Published: November 2024

Recombinant porcine somatotropin is important to the swine industry because it causes high growth
and change in pig carcass composition by converting fat into lean meat. In the present work, we constructed and
expressed an optimized somatotropin molecular construct. Different strains of Escherichia coli were evaluated
for protein expression efficiency. The optimized molecular construct was bioinformatically analyzed resulting
in a molecular weight of 26.44 kDa and a theoretical pI of 6.83. The optimized gene was cloned into the pBAD/
Myc-His A vector which was subsequently transformed using strain TOP10 Escherichia coli strain.
Cloning and expression of avian interferon alpha (ChIFNα) and Newcastle Fusion proteins in Escherichia coli
Authors: Cardoso-Juárez Sheila Saraí , Cano-Buendía José Alberto , González-Lozano Miguel , MoralesArrieta Sandra
Published: November 2024

La industria avícola es afectada por enfermedades virales causando pérdidas económicas.
La producción del Interferón aviar alfa (ChIFNα) y de la proteína de Fusión del Virus de Newcastle
como proteínas recombinantes podrían usarse en el desarrollo de vacunas veterinarias. En este trabajo, las secuencias fueron optimizadas usando el índice de adaptación de codones (CAI) generando
secuencias con un valor de CAI mayor al 0.7. La secuencia optimizada del ChIFNα (579 pb) se clonó en
el vector de expresión pBAD/MycHis-A (4094 pb), sin embargo, se obtuvieron resultados negativos en
el análisis de expresión de la proteína por Western Blot, por lo que el ChIFNα se subclonó en el vector
de expresión pET28a (5369 bp). Se clonó in silico la proteína F optimizada (1665 pb) en el vector de
expresión pBAD/MycHis-A, donde se determinó la longitud y el peso teórico de la proteína recombinante es de 1728 pb y 61.57 kDa.
Development of white corn (Zea mays) on growth pouches with biosolids
Authors: Vera-García Sara Luz , Barrera Cortés Josefina , Cañizares-Villanueva Rosa Olivia , Esparza-García Fernando José , Albores-Medina Arnulfo , Muñoz-Páez Karla , Horcasitas-Montes Ma. del Carmen , Rodríguez-Casasola Felipe Neri
Published: November 2024

Soil improvement through the application of biosolids is a technique used to increase agricultural production by
providing nutrients, water, and organic matter. Its application is subject to the guidelines of NOM-004-SEMARNAT-2002.
The objective of this research is to observe root and plant development when biosolids are added to the soil in a growth
pouch system. The materials under study are characterized as soil and biosolids from a food industry (Bio) and a paper
mill (PC). From the characterization of the biosolids, the nutrients in the form of phosphorus and nitrogen present are
25-82 mg Kg-1 and 120-156 mg Kg-1. The soil to be used is in a moderately deteriorated state due to the lack of phosphorus
and nitrogen. Therefore, the treatments used were 0, 25, 50, 50, 75 and 100 (%) of biosolid and soil mixtures, following
the growth after 12 days. The highest growth was obtained with bio at 25 %; 28.9 cm corresponding to a yield of 82%.
Therefore, this biosolid can be used as fertilizer and increase the production of a crop.
Estudio comparativo del contenido de compuestos fenólicos totales y capacidad antioxidante de los frutos de mangostán (Garcinia mangostana L.) y de rambután (Nephelium Lappaceum L.)
Authors: Lozano-Tavira Citlalli , Avendaño-Arrazate Carlos , Rosales-Martínez Patricia , García-Ochoa Felipe , López-Cortez Ma. del Socorro
Published: November 2024

Las frutas exóticas como el mangostán y el rambután se han incorporado a la dieta occidental debido a
sus propiedades funcionales y sus usos terapéuticos. El mangostán (Garcinia mangostana L.) es una fruta de origen
asiático, perteneciente a la familia de las gutíferas y considerada “la reina de las frutas” por su actividad antioxidante,
antiinflamatoria, anticancerígena y antimicrobiana, propiedades atribuidas a su alto contenido de compuestos bioactivos. El rambután (Nephelium lappaceum L.), es una fruta tropical perteneciente a la familia Sapindaceae, de sabor dulce,
vitamina C y riboflavina y se le atribuyen propiedades medicinales por su contenido en compuestos fenólicos. En el
presente estudio se realizó el análisis fisicoquímico, contenido de compuestos fenólicos totales y capacidad antioxidante
del pericarpio y mesocarpio (cáscara y pulpa) de ambos frutos originarios del estado de Chiapas. Se observó una mayor
capacidad antioxidante por DPPH en el extracto de mesocarpio de mangostán (60.38 μmol trolox/g b.s.), en comparación
con el rambután (44.65 μmol trolox/g b.s.); sin embargo, el epicarpio del rambután presentó mayor actividad antioxidante
por DPPH (178 μmol trolox/g b.s.) que el de mangostán. Con el radical ABTS el epicarpio del mangostán presentó el mayor
valor (297.5 ± 8.86 µMol trolox/g b.s.). El contenido de compuestos fenólicos y la capacidad antioxidante del epicarpio
fue mayor en comparación a las pulpas de ambos frutos. Estos resultados confirman que el mesocarpio de ambos frutos
producidos en nuestro país contiene compuestos bioactivos que son los responsables de su capacidad antioxidante.
Antimicrobial effect of olive and sunflower oils determined by microbial challenge
Authors: Monterrubio-López Gloria Paulina , Mendieta-Pérez Citlali Carolina , Santiago-Carrillo Mariana , Monterrubio-López Ricardo
Published: November 2024

The selection of resistant bacteria is a worldwide health problem that drives the development of new
antimicrobial substances. Some natural oils have antimicrobial compounds that could help in infectious disease
treatment. We determined whether olive and sunflower oils met the microbial reduction specifications to be used
as antiseptic agents. A microbial challenge methodology was used to evaluate olive and sunflower oils against
three reference strains and five clinical isolates (three antibiotic sensitive and two resistant). The neutralizing
toxicity against the strains was previously tested. Two neutralizings were chosen to stop the assay at a defined time.
Olive oil showed greater antimicrobial power than sunflower oil, with reduction percentages greater than 99% in
all bacteria; however, it only met the specification of ≥99.999% reduction against S. aureus, S. epidermidis and
E. coli. Sunflower oil showed reduction percentages of less than 94%, so it is not recommended as an antiseptic
agent. Olive oil can be used as a complementary to antibiotics therapy.
A review of the peptides importance for the biotechnology industry
Authors: Rosales-Valencia Lorena , García-Díaz Cesar , Gómez-Acata Rigel , Camacho-Luengas Dumar , Gómez-Sánchez Carlos , Ahuatzi-Chacón Deifilia , Ordaz Alberto
Published: November 2024

This work pointed out the importance of the peptides within the biotechnology as a biomolecule that have the
capacity to act on the digestive, immune, cardiovascular, and nervous systems, among other to prevent aging, improving
body fat levels, increasing muscle growth efficiency, and controlling hormone levels. Currently there are several strategies
(chemical or biotechnological) to produce peptides depending on its size, scaling-up costs, and time for production.
For the biotechnological approach the main challenges rely on choosing the adequate expression system for peptide
production as well as the correct strategy for massive production (scaling up) and the bioreactor design.
Literatura e inteligencia artificial: convergencias en el aula universitaria
Authors: Sánchez Peña Ada Aurora
Published: November 2024

La literatura, como disciplina humanística, permite a los lectores expandir su percepción sobre el mundo circundante y, también, sobre la condición humana. En este sentido, la literatura posee la facultad de movilizar elementos culturales, históricos, emocionales y, desde luego, estéticos. De ahí que su promoción dentro de contextos escolares sea parte de lo que faculte a un currículo a abrir espacios que promueven la conciencia sobre el actuar social y la posesión de una lengua con todos sus recursos expresivos. Ante la emergencia de la inteligencia artificial (IA), se abren oportunidades para revitalizar las prácticas docentes de cualquier asignatura, incluida la literatura. En el presente ensayo se exponen ejemplos prácticos de cómo hacer un uso lúdico de la inteligencia artificial a través del ChatGPT en una clase de literatura a nivel universitario. Para llegar a esta propuesta, se analizan los aportes de la literatura a una formación integral y lo que ha significado la irrupción de la IA en el campo de la educación. Se concluye que una forma de adelantarse al eventual uso pernicioso de la inteligencia artificial en el aula es promover su empleo crítico, supervisado y ético dentro de la actual e imparable transformación tecnológica.
Formación continua y gestión educativa en la Nueva Escuela Mexicana
Authors: Casamadrid Raúl , Cataño Santiago
Published: November 2024

Para la Nueva Escuela Mexicana la formación continua se constituye como el proceso educativo que tiene por objeto desarrollar y actualizar las habilidades como una constante de aprendizaje en la vida profesional; al tiempo que la gestión educativa procura un proceso de estrategias y actividades que intentan optimizar los recursos a la mano para optimizar la eficiencia y la eficacia de los procesos educacionales. La formación continua es un proceso esencial dada la constante evolución de las tecnologías y técnicas en la búsqueda de fomentar el pensamiento crítico y la resolución de problemas, mientras que la gestión educativa se enfoca en mejorar la calidad de los procesos educacionales en beneficio de la comunidad; ambas, son dos poderosas herramientas que actualizan las prácticas docentes hacia las soluciones de problemáticas reales dentro de cada centro educativo al mejorar las competencias de los profesionales de la educación y asegurar el eficiente funcionamiento de las instituciones educativas en un ámbito de corresponsabilidad y autogestión frente a los la integración de los aprendizajes en el alumnado.
Infection Rate of Theileriosis in Sheep Population in District Kohat
Authors: Majid Hafiz Abdul , Shah Shaheed Ullah , Raziq Abdur , Shoaib Muhammad , Mujtaba Muhammad , Khan Hamayun , Ahmad Israr , Rehman Hafeez Ur , Raza Hafiz Ahsan , Ullah Qamar
Published: November 2024

To Ovine theileriosis, a tick-borne disease caused by Theileria species poses significant economic and health burdens on livestock production worldwide. This cross-sectional study investigated the prevalence and risk factors associated with Theileria infection in sheep populations in District Kohat, Pakistan. A total of 200 blood samples were collected from sheep across four tehsils and examined microscopically. The overall prevalence of theileriosis was 43.5% (95% CI: 36.4-50.6), with significant variations across tehsils (28.9%-49.1%). Multivariate analysis revealed significant associations between Theileria infection and age (p < 0.05), body condition score (p < 0.05), sex (p < 0.05), and season (p < 0.05). Younger sheep (<1 year), males, and those with poor body condition scores were identified as high-risk groups. Seasonal analysis showed a higher prevalence during summer (60%, p < 0.01). The high prevalence of theileriosis in District Kohat highlights the need for targeted interventions and preventive measures to mitigate its impact on sheep production. Improved animal husbandry practices, tick control strategies, and vaccination programs could reduce the disease burden. The study's findings contributed to the ovine theileriosis epidemiology in Pakistan and informed evidence-based control measures.
Evaluating the Iron Deficiency Anemia in Type-II Diabetic Patients Taking Metformin and its Association with Oxidative Stress
Authors: Umer Abdullah , Sarfraz Junaid , Ahmed Hateem , Qayyum Rao Abdul , Parveen Aamira , Manan Zarwa , Qammar Bilal
Published: November 2024

Introduction: Iron deficiency anemia (IDA) is a prevalent nutritional deficiency worldwide, particularly affecting vulnerable groups with chronic illnesses, such as type 2 diabetes mellitus (T2DM). T2DM, characterized by insulin resistance and hyperglycemia, impacts numerous physiological processes and is linked with increased oxidative stress.

Objective: This study aims to examine the prevalence of iron deficiency anemia in T2DM patients taking metformin and to investigate its association with oxidative stress.

Methodology: Conducted at Shalamar Hospital, Lahore, this cross-sectional study took place from September 2023 to September 2024 and included 255 patients aged 30–70 years. Exclusion criteria were patients with chronic kidney disease, liver dysfunction, gastrointestinal disorders affecting nutrient absorption, or those taking iron supplements or medications influencing iron metabolism.

Results: Among the participants, 40.9% (92 patients) were diagnosed with IDA, with a mean hemoglobin level of 11.5 g/dL. In contrast, 59.1% (133 patients) without IDA had a higher mean hemoglobin of 14.3 g/dL. IDA patients showed significantly elevated malondialdehyde (MDA) levels at 3.8 μmol/L, compared to 2.5 μmol/L in non-IDA patients (p < 0.05), suggesting increased lipid peroxidation. Antioxidant enzyme levels were also lower in the IDA group, with superoxide dismutase (SOD) and glutathione peroxidase (GPx) at 150 U/mL and 80 U/mL, respectively, versus 200 U/mL and 100 U/mL in non-IDA patients.

Conclusion: This study concludes that iron deficiency anemia is common among T2DM patients on metformin and is significantly associated with increased oxidative stress
Timing of Primary PCI and Mortality in Acute Myocardial Infarction: Impact of Door to Balloon Time
Authors: Ullah Ikram , Khan Muhammad Idrees , Farooq Umar , Orakzai Muhammad Hafeez , Ullah Abid , Ahmad Sohail
Published: November 2024

Objective: This study aimed to evaluate the impact of door-to-balloon (DTB) time on mortality in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) at Hayatabad Medical Complex, Peshawar.

Methodology: A prospective cohort study was conducted with 400 patients divided into two DTB time groups: "<60 minutes" and "60-90 minutes." Patient data, including age, DTB time, and mortality outcomes, were collected over 12 months (April 2022 to March 2023). Statistical analysis involved descriptive summaries and chi-square tests to assess associations between DTB time and mortality, using a p-value of <0.05 for significance.

Results: Mortality rates were slightly higher in the "60-90 minutes" group (6.1%) compared to the "<60 minutes" group (5.3%); however, chi-square analysis showed no statistically significant association between DTB time and mortality (\( \chi^2 = 0.07 \), \( p = 0.7849 \)). Age distribution was similar across groups, with no meaningful impact on mortality outcomes. The findings indicate that DTB time alone may not be a sufficient predictor of mortality in this cohort, emphasizing the need for a broader focus on total ischemic time and pre-hospital care.

Conclusion: This study suggests that reducing DTB time alone may not significantly affect mortality in STEMI patients, underscoring the need for systemic improvements in pre-hospital and total ischemic time management to optimize patient outcomes.
Examining the Therapeutic Effects of Bioactive Compounds in Orange and Pomegranate for the Management of Acne Vulgaris
Authors: Hamza Muhammad , Aftab Rameesha , Saleem Fizza , Chaudhary Ayesha Umar , Anjum Zahin , Saeed Samina , Shahid Komal , Fatima Memoona , Fatima Ghulam
Published: November 2024

Background: Acne vulgaris is the most common inflammatory skin disorder that affects millions of people globally. Various conventional treatments like topical retinoid as-well-as antibiotics are commonly used, but they have many limitations and side effects. But nutraceuticals are gaining much attention for their therapeutic potential in overall skin health and management of skin disorders especially acne.

Objective: The main objective of this review was to examine the therapeutic potential of bioactive compounds present in orange and pomegranate for the management of acne vulgaris, due to their antioxidant, antimicrobial and anti-inflammatory properties.

Materials and Methods: A comprehensive literature review was conducted using databases such as PubMed and Google Scholar. Studies examining the bioactive compounds of orange and pomegranate and their effects on acne-related factors such as inflammation, sebum production, and bacterial growth were included.

Results: Results from the present review demonstrates that pomegranate contains bioactive compounds like ellagic acid and punicalagins, while orange contains flavonoids, hesperidin and vitamin C that have strong antimicrobial, anti-inflammatory, and antioxidant properties against acne-causing bacteria like P. acnes and Staphylococcus aureus.

Conclusion: Nutraceuticals derived from natural food sources like pomegranate and orange demonstrate the therapeutic potential against the acne causing bacteria. Although existing studies suggested their beneficial effects but further clinical trials are still needed in order to fully establish their efficacy as well as to develop the optimized formulations for the oral and topical use against the treatment of acne.
Comparative Efficacy of Basal-Bolus Versus Premixed Insulin Regimens in Achieving Glycemic Control Among Patients with Type 2 Diabetes Mellitus: A Systemic Review
Authors: Khan Dawood , Zafar Lintha , Faryal Sadaf , DurreBeda Saima , Shakeel Zainab , Waqas Muhammad , Ullah Naqeeb , Nazir Mahwash , Nazir Sumaira
Published: November 2024

Background: T2DM is one of the most prevalent chronic illnesses, requiring effective management to prevent complications. Oral antidiabetic agents are typically needed only in the initial stage to control blood glucose level, while insulin therapy becomes essential as the disease progresses. This includes both basal-bolus and premixed insulin regiments. Therefore, defining an optimal treatment schedule is crucial to improve outcomes in T2DM management and minimize associated attack.

Objective: This systematic review assesses the efficacy and safety of the basal-bolus regimen compared to premixed insulin in treating glycemia in T2DM.

Methods: The study search involved PubMed, EMBASE, Cochrane Library, and Scopus; the search done strictly applied the PRISMA guidelines. A Review of RCTs, cohort studies, and systematic reviews for comparing basal-bolus regimens to the premixed insulin regimens in A-T2DM was done. These were HbA1c, FPG, and PPG. Secondary endpoints were the incidence of hypoglycemia, adherence to therapy, and disease-specific quality of life.

Results: From the above search, we identified 45 studies that meet the inclusion criteria. Daily basal-bolus regimens demonstrated a slightly better reduction in HbA1c, FPG, and PPG than premixed regimens with the trade-offs related to hypoglycemia and regimen complexity. However, basal-bolus regimens are disadvantaged by having more hypoglycemia episodes than the a priori premixed regimens for patients requiring fewer injections.

Conclusion: While basal-bolus regimens give better glycaemic control than premixed ones, the latter are safer and easier to use in some patients. Sources call into question of patient’s characteristics in particular, features of T2DM, the patient’s behavior, and his/her genetic background in order to come up with the most effective and individualized treatment plan more consequently than in any other case.
Comparative Predictors of Long-Term Success in Mesh-Based versus Tissue-Only Hernia Repair: A Meta-Analysis
Authors: Salman Muhammad , ullah Asmat , Rehman Haseena , Bangash Rohail Khan , Safiullah Tahmeedah , Khan Zarmina , Akhtar Ibrahim , Khan Uzair , Saeed Nadia
Published: November 2024

Introduction: Hernia repair ranks among the most commonly performed surgical procedures worldwide, with two predominant approaches: mesh-based and tissue-only techniques. Mesh repairs, while effective in reducing recurrence rates, are associated with complications like chronic pain and foreign body reactions. Conversely, tissue-only repairs avoid these complications but tend to have higher recurrence rates, particularly in complex hernias. This study aims to evaluate long-term predictors of success for both techniques to inform optimal surgical decision-making.

Objective: To compare prognostic factors for mesh-based versus tissue-only hernia repair, emphasizing recurrence rates, complications, and patient-specific outcomes.

Methods: A meta-analysis of randomized controlled trials and cohort studies published between 2000 and 2024 was conducted using PubMed, Scopus, Web of Science, and Cochrane databases. Studies with a minimum follow-up of one year were included. Data were analyzed using random effects models to evaluate recurrence, complications, and patient characteristics.

Results: Mesh-based repairs demonstrated significantly lower recurrence rates, particularly in patients with large hernias or higher BMI. Lighter-weight meshes were associated with reduced chronic pain. Tissue-only repairs were more suitable for younger, slimmer patients with smaller hernias, demonstrating fewer complications but higher recurrence rates in complex cases. The findings underscore the importance of tailoring the surgical approach to patient-specific factors.

Conclusion: The results highlight the need for individualized surgical strategies in hernia repair. Mesh-based techniques are recommended for complex cases due to their lower recurrence rates, while tissue-only repairs are more suitable for young, low-risk patients. These insights can guide clinicians in selecting the most appropriate repair technique, improving patient outcomes and satisfaction.

By focusing on long-term predictors of success, this study provides a comprehensive evaluation of mesh-based and tissue-only hernia repairs, offering valuable guidance for patient-centered surgical decision-making.
Primary PCI in Diabetic Patients: Clinical Outcomes and Challenges
Authors: Shah Hamid Ali , Khan Muhammad Niaz , Waris Abdul , Ali Nasir , Saeed Ihtisham , Hafeez Muhammad
Published: November 2024

Objective: To evaluate clinical outcomes and procedural challenges in diabetic patients undergoing primary Percutaneous Coronary Intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) at the Department of Cardiology, Hayatabad Medical Complex, Peshawar.

Methodology: Conducted as an observational, single-center study from July 2022 to June 2023, 300 patients were enrolled, with equal numbers of diabetic and non-diabetic patients. Baseline demographics, clinical outcomes, and procedural success were analysed. Statistical tests included chi-square for categorical variables (major adverse cardiac events (MACE), stent thrombosis, restenosis, TIMI flow) and t-tests for age comparison. A significance level of p < 0.05 was set.

Results: Diabetic patients had a mean age of 60.9 years compared to 59.9 years in non-diabetic patients (t = -0.41, p = 0.685). The distribution of MACE was similar between groups (χ² = 1.31, p = 0.727), as were rates of stent thrombosis (χ² = 0.00, p = 1.000) and restenosis (χ² = 0.85, p = 0.355). TIMI flow rates also showed no significant difference by diabetic status (χ² = 3.32, p = 0.190), indicating comparable outcomes between diabetic and non-diabetic patients.

Conclusion: The study found no significant differences in primary PCI outcomes between diabetic and non-diabetic patients, suggesting that standardized procedural protocols may mitigate the heightened risk profile of diabetic patients. Multicenter studies with advanced diagnostic tools are recommended to enhance generalizability and optimize outcomes further in this population.
The Association Between Pulmonary Embolism and Long-Term Cardiovascular Disease Progression: A Meta-Analysis of Heart Failure, Pulmonary Hypertension, and Hospitalization Rates
Authors: Aurangzeb Laraib , Tayyab Muhammad , Umar Zeeshan , Ahmad Zaheer , Khan Muhammad Shamoon , Hunain Muhammad , ullah Sana , Ali Maaz , Safdar Sundas , Malik Aqleema
Published: November 2024

Background: Pulmonary embolism (PE) presents great acute danger and its chronic effects on cardiovascular organization is an important, however investigated aspect. People who survive PE is subjected to higher vulnerability to develop long-term diseases including heart failure as well as pulmonary hypertension and also exhibit higher hospital admission rates. It is therefore important to grasp these risks in an effort to get the best out of the treatment to the patients.

Objectives: The current meta-analysis has been designed to look at the relationship between PE and the development of long-term CV disease, specifically heart failure, pulmonary hypertension, and the rates of hospitalization.

Methods: As it follows the international PRISMA guidelines, we conducted an extensive literature search of the PubMed, Cochrane, Scopus, and Embase databases using terms up to November 2024. The present review includes only those studies that were evaluated on long-term cardiovascular consequences after the disease affecting PE patients. The data were collected and reviewed by two authors, and quality assessment was performed using specific criteria; pooled ORs were calculated using the random effects model for reasons of heterogeneity.

Results: The researchers included 54 studies covering more than 42,000 patients in the analysis. The meta-analysis showed that PE survivors have a significantly increased risk of heart failure (OR = 1.80, 95% CI: 1.Their prevalence rate was 45-2.22 times higher than expected among patients with heart failure (OR = 2.15, 95% CI: 1.75-2.64) and pulmonary hypertension. Additionally, hospitalization rates were notably higher in this population (OR = 1.50, 95% CI: 1.20-1.87).

Conclusion: The results of this study re-emphasize the importance of continuous follow-up of cardiovascular status and individualized care for patients after a PE to prevent the development of serious late effects. Even if great advances have been made in the identification of new therapies and treatments for coronary disease, the prompt and proper management of the risk factors responsible for recurrent cardiovascular events could have a beneficial impact on patient’s prognosis and lower healthcare expenditures
Outcome of Breast feeding mothers with infants under 6 months admitted to Kohat district hospital
Authors: Zakir ullah Dr
Published: November 2024

BACKGROUND: Exclusive breastfeeding within the first six months of infancy is one of the main goals of global public
 health.There is evidence linking early breastfeeding termination to several factors, including the reasons given by women for quitting. The purpose of this study was to describe the actual nursing practices and the stated intentions of women to breastfeed, as well as to examine the correlations between different parameters at Lady Reading Hospital.
METHODOLGY: the study subject to the greatest extent possible by using this convergent design "to obtain different but complementary data on same topic." At Kohat District Hospital's Peads OPD & Ward, a cross-sectional study was carried out with ethical approval.
RESULT:  The age group under 35 had the highest percentage, at 151 (69%). 118 people, or 54%, had primary level education, which was more than other factors. There was a lower employment ratio among working mothers (87, 40%). The store milk had the highest percentage of respondents not answering (19), but everyone had the same opinion about breast milk as the first food after birth. For water utilization, 22 moms gave the same response. Thirty-three women did not respond, 89 were safe, and 97 mothers had depression. 137 babies received colostrum, whereas 107 (48%) of them received hand washing as part of their hygiene routine. Thirty-one moms, or eighteen percent, utilized medication for lactation.
CONCLUSION:  For the mother and the child, proper hygiene is crucial. Education and support are beneficial after the initial delivery. Health care professionals should visit all expectant moms to provide education and advice on sanitary care, as well as to monitor postpartum depression.