bluuebunny/crossref_metadata_2025 huggingface dataset:
Implications of the gut microbiome in cardiovascular diseases: Association of gut microbiome with cardiovascular diseases, therapeutic interventions and multi-omics approach for precision medicine
Authors: Meenatchi Ramu , Singh Prabhakar , Ahmed Z.H Tawfeeq , THACHARODI ASWIN , M Rohinth , KUMAR REJITH RS , K HARSHA VARTHAN M , HASSAN SAQIB
Published: August 2023

Cardiovascular diseases (CVDs) remain a major global health burden, and
emerging evidence suggests that the gut microbiome plays a pivotal role
in their pathogenesis and progression. This review paper aims to
comprehensively analyze the intricate interplay between the gut
microbiome and cardiovascular health. An extensive examination of
existing literature explores how gut microbial composition and function
influence CVD risk factors, such as inflammation, lipid metabolism, and
blood pressure regulation. Additionally, we delve into the impact of
dietary patterns, medications, and lifestyle factors on shaping the gut
microbiota and how these changes can either exacerbate or ameliorate
cardiovascular outcomes. Furthermore, we discuss the potential of gut
microbiome-targeted interventions as promising avenues for preventing
and managing CVDs. By consolidating the current state of knowledge, this
review aims to shed light on the intricate link between the gut
microbiome and cardiovascular diseases and highlights the potential for
novel therapeutic strategies to combat this significant public health
challenge.
H2O2 enhances spontaneous contractions of human-bladder strips via activation of TRPA1 channels on sensory nerves and release of substance P and PGE2
Authors: Wang Haoyu , Zhao Mengmeng , liu jiaxin , liu lei , liu hanwen , ding ning , Wang Shaoyong , Ge Nan , Zhang Xiulin
Published: August 2023

Abstract Background and purpose: Several studies have indicated that
reactive oxygen species (ROS) can lead to detrusor overactivity (DO),
but the underlying mechanisms are not known. Hydrogen dioxide (H2O2) is
used commonly to investigate the effects of ROS. In present study, we
aimed to investigate the effects of H2O2 on phasic spontaneous bladder
contractions (SBCs) of isolated human-bladder strips (iHBSs) and the
underlying mechanisms. Experimental approach: Samples of bladder tissue
were obtained from 26 patients undergoing cystectomy owing to bladder
cancer. SBCs of iHBSs were recorded in organ-bath experiments.
Immunofluorescence staining was conducted to confirm the TRPA1
expression on sensory nerves. Key results: H2O2 (1μM–10mM)
concentration-dependently increased the SBCs of iHBSs. These enhancing
effects could be mimicked by an agonist of transient receptor potential
(TRP)A1 channels (allyl isothiocyanate) and blocked with an antagonist
of TRPA1 channels (HC030031; 10μM). H2O2 induced enhancing effects also
could be attenuated by desensitizing sensory afferents with capsaicin
(10μM), blocking nerve firing with TTX (1μM), blocking neurokinin
effects with NK2 receptor antagonist (SR48968, 10μM), and blocking PGE2
synthesis with indomethacin (10μM), respectively. Conclusions and
implications: Our study: (i) suggests activation of TRPA1 channels on
bladder sensory afferents, and then release of substance P or PGE2 from
sensory nerve terminals, contribute to the H2O2-induced enhancing
effects on SCs of iHBSs; (ii) provides insights for the mechanisms
underlying ROS leading to DO; (iii) indicates that targeting TRPA1
channels might be the promising strategy against overactive bladder in
conditions associated with excessive production of ROS.
How Early Digital Experience Shapes Young Brains: A Scoping Review
Authors: Wu Dandan , Dong Xinyi , Liu Danqing , Li Hui
Published: August 2023

Early digital experience (e.g., screen time and digital use) is believed
to impact children’s brain development, functionally and structurally,
but this impact has not been systematically reviewed. In this scoping
review, we synthesized and evaluated 33 collected studies on children’s
digital use (ages 0-12) and their associated brain development published
between January 2000 and April 2023. The synthesis of the evidence
revealed that: (1) digital experience does have positive and negative
impacts on children’s brains, structurally and functionally; (2) it
could cause structural and functional changes in children’s frontal,
parietal, temporal, and occipital lobes, brain connectivity, and brain
networks; and the most vulnerable area is the prefrontal cortex and its
associated executive function; (3) early digital experience has both
positive and negative impacts on children’s brain structure
longitudinally. The limitations and implications for future studies are
also discussed.
CUT&tag: A powerful epigenetic tool for chromatin profiling
Authors: Li Peipei , fu zhijun , jiang sanjie , sun yiwen , zheng shanqiao , zong liang
Published: August 2023

Analysis of transcription factors and chromatin modifications at the
genome-wide level provides insights into gene regulatory processes, such
as transcription, cell differentiation and cellular response. Chromatin
immunoprecipitation is the most popular and powerful approach for
mapping chromatin, and other enzyme-tethering techniques have recently
become available for living cells. Among these, CUT&Tag is a relatively
novel chromatin profiling method that has rapidly gained popularity in
the field of epigenetics since 2019. It has also been widely adapted to
map chromatin modifications and TFs in different species, illustrating
the association of these chromatin epitopes with various physiological
and pathological processes. Scalable single-cell CUT&Tag can be
combined with distinct platforms to distinguish cellular identity,
epigenetic features and even spatial chromatin profiling. In addition,
CUT&Tag has been developed as a strategy for joint profiling of the
epigenome, transcriptome or proteome on the same sample. In this review,
we will mainly consolidate the applications of CUT&Tag and its
derivatives on different platforms, give a detailed explanation of the
pros and cons of this technique as well as the potential development
trends and applications in the future.
Computing time dilation between inertial frames
Authors: Seagraves David A.
Published: August 2023

The concepts underlying the Lorentz transform for time dilation and
length contraction are presented. The notion of a rest frame is
introduced and its usefulness discussed. The rest frame of the CMB (the
Hubble frame) is proposed as the correct candidate for the rest frame in
the Lorentz transform, and an equation developed to compute the relative
time dilation between inertial frames based on this assumption.
COVID-19 vaccine adverse events: Evaluating the pathophysiology from an undersulfated and degraded glycocalyx perspective
Authors: Preez Heidi N du , Lin Johnson , Maguire Glenn E M , Aldous Colleen , Kruger Hendrik G
Published: August 2023

In this literature review, we assess the pathophysiology of severe
adverse events observed after vaccination with DNA and mRNA vaccines
against COVID-19, despite reports of their overall effectiveness. The
focus is on the perspective of an undersulfated and degraded glycocalyx,
considering its impact on immunomodulation, inflammatory responses,
coagulation, and oxidative stress. The paper explores various factors
that lead to glutathione and inorganic sulfate depletion and their
subsequent effect on glycocalyx sulfation and other metabolites,
including hormones. Components of COVID-19 vaccines, such as DNA and
mRNA material, spike protein antigen, and lipid nanoparticles, are
involved in possible cytotoxic effects. The common thread connecting
these adverse events is endotheliopathy or glycocalyx degradation caused
by depleted glutathione and inorganic sulfate levels, shear stress from
circulating nanoparticles, aggregation, and formation of protein
coronas, leading to imbalanced immune responses and chronic release of
pro-inflammatory cytokines, ultimately resulting in oxidative stress and
systemic inflammatory response syndrome. By understanding the underlying
pathophysiology of severe adverse events, better treatment options can
be explored.
A quantitative comparison and validation of finite-fault models: The 2011 Tohoku-Oki earthquake
Authors: Wong Jeremy Wing Ching , Fan Wenyuan , Gabriel Alice-Agnes
Published: August 2023

Large earthquakes rupture faults over hundreds of kilometers within
minutes. Finite-fault models elucidate these processes and provide
observational constraints for understanding earthquake physics. However,
finite-fault inversions are subject to non-uniqueness and substantial
uncertainties. The diverse range of published models for the
well-recorded 2011 M_w 9.0 Tohoku-Oki earthquake aptly illustrates this
issue, and details of its rupture process remain under debate. Here, we
comprehensively compare 32 finite-fault models of the Tohoku-Oki
earthquake and analyze the sensitivity of three commonly-used
observational data types (geodetic, seismic, and tsunami) to the slip
features identified. We first project all models to a realistic
megathrust geometry and a 1-km subfault size. At this scale, we observe
poor correlation among the models, irrespective of the data type.
However, model agreement improves significantly when subfault sizes are
increased, implying that their differences primarily stem from
small-scale features. We then forward-compute geodetic and teleseismic
synthetics and compare them with observations. We find that seismic
observations are sensitive to rupture propagation, such as the
peak-slip-rise time. However, neither teleseismic nor geodetic
observations are sensitive to spatial slip features smaller than 64 km.
In distinction, the synthesized seafloor deformation of all models
exhibits poor correlation, indicating sensitivity to small-scale slip
features. Our findings suggest that fine-scale slip features cannot be
unambiguously resolved by remote or sparse observations, such as the
three data types tested in this study. However, better resolution may
become achievable from uniformly gridded dense offshore instrumentation.
Trends and Drivers of Income Inequality in the Philippines, Thailand, and Viet Nam: A Decomposition Analysis
Authors: Mercado Rogelio , Park Cyn-Young , Zhuang Juzhong
Published: August 2023

This paper examines the factors that have driven income inequality moderation in the Philippines, Thailand, and Viet Nam over the past 2 decades. A decomposition of income inequality and its changes by income sources and household characteristics found that wage, nonfarm business income, and overseas remittance concentrations declined as less well-off households increasingly engaged in better-paying activities. Moderating income inequality might be the combined outcome of rising income opportunities, government policies promoting social inclusion, and positive impacts of structural transformation. Nonetheless, income inequality remains high, especially in the Philippines and Thailand. More policy efforts are still needed to make growth more inclusive.
Adherence to a Web-based Exercise Programme: A Feasibility Study Among Patients with Hip or Knee Osteoarthritis
Authors: Joseph Kenth-Louis , Dagfinrud Hanne , Hagen Kåre Birger , Nordén Kristine Røren , Fongen Camilla , Wold Ole-Martin , Hinman Rana S. , Nelligan Rachel K. , Bennell Kim L. , Tveter Anne Therese
Published: August 2023

Objectives: To describe adherence to a 12-week web-based aerobic exercise programme, to compare characteristics between those who adhere or not, and to identify barriers for exercising in patients with hip or knee osteoarthritis.
Design: Single-arm feasibility study.
Subjects: Patients with hip or knee osteoarthritis in specialist healthcare, age 40–80 years, and not candidates for joint surgery.
Methods: Adherence to a 12-week exercise programme was defined as having completed ≥ 2 exercise sessions a week for at least 8 weeks. Baseline differences between adherent and non-adherent groups in demographics, symptoms, disability, physical activity and fitness were assessed using Mann–Whitney U or χ2 tests. Reasons for not completing exercise sessions were reported in weekly diaries. 
Results: A total of 29 patients (median age 64 years, 72% female) were included. Median baseline pain (numerical rating scale 0–10) was 5. Fifteen patients adhered to the exercise programme, 14 did not. Non-adherent patients were less active (p = 0.032) and had lower cardiorespiratory fitness (p = 0.031). The most frequently reported barrier to exercising was sickness. Less than 10% reported pain as a barrier.
Conclusion: Half of the patients with hip or knee osteoarthritis adhered to the digitally delivered exercise programme and the most frequently reported barrier for adherence was sickness, while less than 10% reported pain as a reason for not exercising.
Trial registration: ClinicalTrials.gov, NCT04084834. The Regional Committee for Medical and Health Research Ethics South-East, 2018/2198.
LABOR WELFARE AFFECTS EMPLOYEE PERFORMANCE AND IS MEDIATED BY WORK SPIRIT
Authors: Sarman Rohmat , Kartika Ranti
Published: August 2023

This study aims to analyze how the influence of labor welfare on employee performance is mediated by morale at PT. Area PGE Kamojang, either directly or indirectly. The research method used was a descriptive and verification method with a total sample of 74 employees. Data collection techniques used were interviews, questionnaires, and observation. Data analysis methods used in this study include path analysis, multiple linear regression analysis, coefficient of determination, and hypothesis testing. The results of the study show that the welfare of the workforce has a direct effect on morale. Labor welfare has a direct effect on employee performance, just as work enthusiasm has a direct effect on employee performance. Then, the results of the analysis also show that morale can mediate the influence of labor welfare on employee performance.
ENTREPRENEURSHIP KNOWLEDGE AND LOCUS OF CONTROL IN INCREASING INTEREST IN ENTREPRENEURSHIP
Authors: Ratnamiasih Ina , Rohmah Dewi
Published: August 2023

This study aims to determine the effect of entrepreneurial knowledge and locus of control on student interest in entrepreneurship. The research method used is a quantitative method with data collection using a questionnaire on a sample of 291 students. The data analysis technique used multiple linear regression and multiple correction. To test the hypothesis and the coefficient of determination using the SPSS 26 program. The results showed that the influence of entrepreneurial knowledge had an effect of 23% while the locus of control was 55.5% on student interest in entrepreneurship. The total influence of entrepreneurial knowledge and locus of control on entrepreneurial interest is 78.5%. The results of this study reinforce the importance of the higher education curriculum in paying attention to entrepreneurial knowledge and increasing student locus of control to increase student interest in entrepreneurship
TRANSNATIONAL CORPORATIONS AND ECONOMIC GROWTH IN NIGERIA
Authors: Nma Okechukwu Okoroji , Chinedu Egbunike , Nonso Okoye , Widiyanti Marlina
Published: August 2023

Prior studies have mainly attributed the reason for suboptimal economic growth rate in Sub-Saharan Africa as home-made majorly caused by misguided economic policies which have distorted the flow of Foreign Direct Investment (FDI) inflows to the region despite efforts of Transnational Corporations in the region and its growing presence in her core sectors. In view of these, the main objective of this study is to examine the relationship between Gross Domestic Product and economic growth in Nigeria. The study is anchored on Internalization Theory. The study relied on secondary sources of data obtained from CBN Statistical Bulletin and National Bureau of Statistics for the period 1999-2018. The data was analysed using descriptive and inferential statistics. The results revealed a significant positive effect of FDI inflows on Gross Domestic Product in Nigeria. Based on this, the study recommends among others that the need for government to woo more of transnational firms in the various sectors of the economy in order to gain the advantage of technology transfer to Nigeria.
THE EFFECT OF EMOTIONAL INTELLIGENCE AND PARTICIPATORY PROCEDURAL JUSTICE ON JOB SATISFACTION
Authors: Fauzi Haris , Juniarti Atty
Published: August 2023

Human resources are the main production factor for organizations to achieve planned goals. Job satisfaction is important because in an organization employees are most dominant as a determinant of organizational success, this is due to high satisfaction being able to create a pleasant atmosphere so that employees are encouraged to excel in their organization. This study aims to determine the effect of participatory emotional intelligence and procedural justice on employee job satisfaction. In this study apply descriptive and verification methods. The population is all employees with a sample of 60 people selected through saturated sampling. testing with validity test and reliability test. Researchers used multiple linear regression and hypothesis testing with partial tests. This study found that emotional intelligence can have a significant positive effect on job satisfaction, and participatory procedural justice has a significant positive effect on job satisfaction.
EFFECTS OF PERCEIVED USEFULNESS, EASE OF USE, RISKS, AND INFORMATION QUALITY OF SALES PRODUCTIVITY APPS ON DSA’S BEHAVIOR
Authors: Kurniasari Florentina , Gunardi Ardi
Published: August 2023

Technological advancements have brought innovation in the financial industry with various platforms. Although these platforms are easily accessible, some Indonesians are still reluctant to use them, hence the need for proper introduction and information delivery. Peer-to-peer (P2P) lending platforms need to develop and implement applications that can monitor the activities and increase the productivity of direct sales agents (DSAs) to gain the trust of potential borrowers. This study analyses the influence of perceived usefulness, ease of use, risk, and information quality on the actual behaviour of DSAs when using sales productivity applications with behavioural intention as an intervening variable to be statistically processed using the Structural Equation Method. The questionnaire was distributed to DSAs of Modalku platform. The results showed that DSA's actual behaviour in using the application was significantly influenced by intention to use, perceived usefulness, ease of use, risk, and information quality. Perceived risk has the highest influence.
Características, focos de pesquisa e tendências sobre liderança na gestão de projetos: uma análise bibliométrica
Authors: Casemiro Ítalo Paula , Azevedo-Ferreira Maxwel De
Published: August 2023

Objetivo: A literatura científica destaca o papel fundamental que a liderança exerce na gestão de projetos. Tendo em vista a relevância da liderança na gestão de projetos, o presente estudo objetiva mapear a produção científica acerca da temática liderança, no âmbito da gestão de projetos.

Método: O estudo foi conduzido por meio de uma análise bibliométrica de 789 artigos obtidos na base Web of Science. apresenta uma série de indicadores e tendências predominantes nas pesquisas acerca da liderança em projetos. Os estudos foram analisados com o auxílio dos softwares Bibliometrix R-tool e VosViewer, por meio de indicadores bibliométricos.

Principais Resultados: O estudo destaca um número crescente de publicações, focadas especialmente em competências da liderança. Estados Unidos é o país expoente na produção, e o periódico International Journal of Project Management é aquele mais utilizado para a publicação sobre este tópico. A análise temática, identificou alguns agrupamentos temáticos, com destaque para temas básicos/tradicionais, como a inovação, gestão da mudança e equipe de projeto e; temas motores como a sustentabilidade, trabalho em equipe e outros mais recentes, como a melhoria contínua em projetos.

Relevância/Originalidade: A pesquisa apresenta um panorama da pesquisa sobre liderança na gestão de projetos, oferecendo insights importantes sobre estas duas áreas de conhecimento: liderança e gestão de projetos.

Contribuições Teóricas: O presente documento oferece aos gestores e interessados na liderança em projetos uma base útil para o desenvolvimento de programas de liderança e futuras pesquisas sobre o tema, no âmbito da liderança em projetos.
Adaptasi Pustakawan dalam Menghadapi Kemajuan Teknologi Informasi di Perpustakaan Perguruan Tinggi Bina Sriwijaya
Authors: Sari Aulia Permata , Yoanda Sely
Published: August 2023

Information technology is an information that is formed in detail and simply by going through the delivery process from the sender to the recipient with a fast process. The role of libraries in this information technology era is very helpful for librarians and users. The method used in this study is a qualitative research method using descriptive research and data collection by using interviews, observation and literature review. The object of this research study is Bina Sriwijaya College. Mastery and application of information technology at Bina Sriwijaya College can be said to still use the old way. The use of information technology for user needs is still in the process of digitizing. The development of a digital library or e-library for library management staff can help work in the library through the function of the library automation system.
INSLISLITE EVALUATION IN THE PROCESSING OF LIBRARY MATERIALS TOWARD USABILITY MODEL
Authors: Putri Indira Adiadwi , RA Okta Reni Azrina , Kesuma Aghesna Rahmatika , Iqbal Rahmat
Published: August 2023

An information system can ease the user in receiving information.  The library needs to use effective and efficient service by using the information system. Processing of library materials is important to do to facilitate the search for information and expedite service activities. This research has a case study at the Bandar Lampung City Library and Archives Service which has used the INLISLite system since 2014. But until now they are still using INLISLite version 3.1. This study uses a qualitative descriptive method by conducting field research on the problems that occur, as well as interacting directly with librarians. INLISLite version 3.1 which is used displays several menus such as Back Office, Read on Place, Guest Book, Online Membership, Digital Collection Services, OPAC, Articles, Member Registration, Statistics, Surveys, Self-Returns, and Self Borrowing. The results first result from the study, librarians can process library materials on the Back Office menu. The second is there are no problems in the learnability and efficiency aspects because in this aspect the INLISLite system makes it very easy for librarians, but there are problems in the Memorability, Error, and Satisfaction aspects.
Self-Regulated Learning on Santri: The Personality Type, Spiritual Intelligence, and Social Support
Authors: Subchi Imam , Badranaya Djaka , Bachmid Achmad , Nufus Amelia Zakiyyatun , Muhammadiyah Hilmi
Published: August 2023

In learning, students should possess the capability to manage their learning effectively to achieve optimal outcomes. Consequently, self-regulated learning becomes crucial for students, encompassing not only general subjects but also religious studies. This research investigates the influence of Personality Type, Spiritual Intelligence, and Social Support on Self-Regulated Learning at Al-Nahdlah Islamic Boarding School. Employing a quantitative method, this study adopts a correlation approach. The sampling technique utilized is probability sampling, specifically stratified random sampling. From 116 students at Al-Nahdlah Islamic Boarding School, a sample of 56 was chosen. For validation, this research employs Confirmatory Factor Analysis (CFA) using the Lisrel 8.7 software. Subsequent data analysis was conducted using multiple regression analysis in the SPSS software. Findings indicate a significant influence of Personality Type, Spiritual Intelligence, and Social Support on Self-Regulated Learning among Al-Nahdlah Islamic Boarding School students. The combined contribution of these independent variables to Self-Regulated Learning is 29.0%, leaving 71.0% influenced by other factors. Thus, Personality Type, Spiritual Intelligence, and Social Support significantly impact students' self-regulated learning capabilities. By enhancing students' spiritual intelligence, understanding their personality types, and strengthening their social support networks, institutions can better foster self-regulated learning capabilities, leading to improved academic outcomes and holistic student development.
Activities of Prosvita and the Volyn ukrainian association in Volyn in the interwar period
Authors: Makar Yuriy , Kucherepa Mykola
Published: August 2023

According to the authors, the current aggression of the Russian Federation against Ukraine permanently deprives Ukrainians of any hope of compromise with their north-eastern neighbour, which is trying to prove the invalidity of a self-sufficient Ukrainian statehood in any way, failure of Ukrainians to create and develop their sovereign state. It has done this throughout all previous centuries, in every way destroying any attempts by Ukrainians to cultivate their own identity. This undoubtedly applies to the use of the mother tongue, the activities of all cultural and educational centres, etc. Attempts by Ukrainians to recreate the Ukrainian state after World War I failed due to internal and external factors, among which the Russian played not a minor role. Russia, then a Bolshevik state, saw no other path to its development than ownership of Ukrainian lands and domination of the Ukrainians. To this end, the most brutal methods of persecution of rebellious Ukrainians were used - from the liquidation of any public organizations to the mass destruction of their carriers. During the interwar period, the part of the Ukrainian lands which later, during and after World War II, the USSR (the same Russia, only under a pseudonymise of the federation of "independent" states) seized, in agreement with then Hitler’s Germany, belonged to other states, including Poland. Taking into account what is happening now, the authors would like to dwell briefly on the activities of Ukrainian educational organizations of the time in Volyn, which was under the authority of Poland. The article analyzes the activity and significance of the Ukrainian national cultural centers in Volyn – Prosvita and Prosvita Houses. It is noted that due to the implementation of the “Volyn experiment” voivod H. Yuzevsky destroyed the cultural and educational society Prosvita in the province under various acutenesses and created societies that were supposed to implement the program of governorates. On the basis of the analysis of many facts, the authors came to the conclusion that cultural and educational organizations subordinated to the Volyn Ukrainian Association, contrary to the hopes of the Polish authorities, had little beneficial influence on the development of culture, education, and literature in Volyn. Further experience showed that after the annexation of Volyn to the USSR, using the slogans of liberation of Ukrainians from the Polish oppression, led to the extermination of all centers of both Polish, and Ukrainian cultural and educational activity, because they did not fit into the Soviet interpretation of human rights and democracy as such. There is no doubt that after the end of the current unprovoked bloody war, which Ukraine will eventually win, with the direct comprehensive assistance of the same Poland and the entire civilized world, the problem of eliminating the layers of alienation between Ukrainians and Poles will be viewed from the perspective of what brings us closer rather than separate.
On the history of maxillofacial traumatology
Authors: Belikov Oleksandr , Moysey Antoniy , Belikova Natalia , Belikova Liudmila
Published: August 2023

The article presents a scientific and historical review of the literature on the development of maxillofacial traumatology. The purpose of the study is to analyze the data from the literature sources regarding the chronology of maxillofacial traumatology development, to identify positive and negative aspects. To achieve this goal, the bibliosemantic method was used to clarify the state of the problem, and the results of previous scientific research were analyzed based on literature and electronic resources. The main part. The literature presents data on the historical stages of development of maxillofacial traumatology, the principles of care for injuries of the craniofacial area, the development of orthopedic structures for repositioning and fixation of jaw fragments, as well as their complications in a scattered and sometimes contradictory manner. Options for repositioning and fixation of mandibular fragments, instruments and devices are presented, and construction materials are described. Conclusion. Historical facts have been clarified, interesting details have been reported, and rare documents have been cited. In today's warfare, we are witnessing an increase in the number of soldiers with traumatic injuries of the maxillofacial area, post-traumatic defects and facial deformities, which are the result of inadequate and untimely medical care on the battlefield. Therefore, based on historical experience, it is necessary to have an algorithm of actions for such injuries directly on the battlefield, in hospitals and rehabilitation centers.
The word as a weapon (about neologisms being a linguistic reflection of the russia-ukraine war)
Authors: Tkach Alla , Tkach Maksym
Published: August 2023

The functioning of the Ukrainian language takes on special importance in the conditions of a full-scale Russian-Ukrainian war. Language is an important component of national identity, a powerful productive tool that strengthens the nation and enriches national culture. The purpose of the article is to describe and systematize innovative processes in the modern national lexical system of the Ukrainian language, which developed during the Russian-Ukrainian war. The article presents new resources of language thinking - neologisms and occasionalisms, which verbalize the current events of the wartime in Ukraine and remind of the close connection between history and language. An overview of linguistic studies on language as a weapon was made; the need for a new nomination is substantiated; examples are considered and the main functions of neolexes are defined; the emotional and expressive component in such word formation is noted; attention is focused on the active functioning of neologisms in the language; the prospects for the study of neologisms against the background of modern events in Ukrainian society and the world are outlined. Research methods. For the scientific interpretation of actual material, we use such general scientific methods as observation and analysis of linguistic material. We use the descriptive method, methods of component and linguistic stylistic analysis. Conclusions. The factual material of the article proves that the word is a special weapon on the language front. The formation and active functioning of new lexical units in military discourse is a kind of reflection of contemporary events; a vivid manifestation of the vocabulary of the Ukrainian language and the high intellectual potential of the Ukrainian people; attesting to the dynamism, continuity and uniqueness of language as a living organism.
Vasyl Kozhelyankо’s Dramaturgy as a phenomenon of modern Ukrainian literature
Authors: Anistratenko Antonina
Published: August 2023

The purpose of the article is to consider the originality and analyze the plays of V. Kozhelyanko in the context of modern dramaturgy and special subgenre, what is called "plays for reading". The novelty of the study is that the dramaturgical heritage of V. Kozhelyanko (in co-authorship with V. Serdyuk) became the object of a comparative study for the first time and has not yet been systematically introduced into the modern literary process in Ukraine. Research methods used in the article are subject to the comparative principle of presentation of the material, combine descriptive and functional-pragmatic methods of analysis. Conclusions. Architectural and genre-stylistic findings of V. Kozhelyanko in the dramatic genre of writing not only laid the foundation of his creative block, in particular the novel in the genre of alternative history and adventure postmodern and newmodern novels, but also formed a workshop of the latest creative tools used by other modern authors (for example, Neda Neshdana). The plays of V. Kozhelyanko are considered in the key of genre and style analysis. Having analyzed some aspects of dramatic texts (the image of the national hero, historical and political figures in the writer's parodic prose, historical and detective novels and the realization of the chronotope in them as a distinguishing genre marker, emphasis on the mental mistakes of the Ukrainian nation as the leitmotif of the creative intention of V. Kozhelyanko) from the point of view of structural , descriptive, receptive and comparative approaches of literary science, we have good reason to talk about the work of V. Kozhelyanko as an example of high-quality modern neomodernist work of the European level.
European models of festive communication: national and international
Authors: Kurochkin Oleksandr
Published: August 2023

A holiday is an eternal and global category of human existence. All tribes and peoples had and have their own system of celebrations, and solemn events designed to unite people, protect and promote the values around which society organizes its life. The purpose of the article is to show the historically determined uniqueness of national holidays and to trace the trend towards the creation of a pan European fund of mass holiday culture using concrete examples. The methodology of the article is based on descriptive and comparative methodological approaches of ethnological studies. Scientific novelty. The article examines historically formed models of holiday traditions of the peoples of Europe, which reflect the specifics of the state system of each country, and those that have gained international distribution. Conclusions. Holidays change throughout historical development depending on economic, political and cultural transformations. The study made it possible to trace the processes of detraditionalization of European society and the associated transition to new modern forms of mass culture.
Secondary nomination in medical discourse from the perspective of cognitive-communicative strategies
Authors: Shutak Larysa , Navchuk Halyna
Published: August 2023

The study of medical discourse is one of the key problems of cognitive-communicative grammar, since the sublanguage of medicine - with all its forms and means of expression and general use - is an integral part of any national language. The analysis of professional speech in various communicative situations is of interest to both Ukrainian linguists and researchers of other Slavic languages. The goal of scientific research is to investigate the ways of creating secondary nominative units in medical discourse and to establish their types according to various characteristics. The article summarizes various reasons for the creation of secondary names in modern linguistics, defines the role and significance of the secondary nomination in the process of replenishing the vocabulary of the modern Ukrainian language. The emergence of secondary nominations is caused by both intra-linguistic and extra-linguistic factors. The creation of such names is due mainly to changes in society, which contribute to the deepening of knowledge about objects and phenomena of the real world, the principle of linguistic economy when creating new words, and emotional and expressive factors. The primary nomination, based on object-sensory perception, is a generalization of social experience and the creation of a conceptual level of knowledge, the secondary nomination generalizes linguistic evidence. The main methods of research are: method of component analysis, method of modeling, method of associative experiment and method of cognitive analysis. Conclusions. The role of secondary nomination as a text category is defined, in particular in binary contrasts. It was found that metaphorization is the most productive means of creating secondary names in medical discourse. A typical way of creating secondary names of persons is suffixation as an ancient and traditional way of creating words. The advantage of secondary suffixed names over official foreign terms is that they are more understandable primarily to patients
CLINICAL VARIANT OF OSSIFYING MYOSITIS IN PEDIATRIC PRACTICE
Authors: Senatorova H. , Frolova T. , Senatorova A. , Kikhtenko O. , Osman N.
Published: August 2023

Introduction. Ossifying myositis is a pathological process in muscles characterized by the formation of ossification in soft tissues. At present, the etiological factors of the disease remain not fully elucidated. The triggering factors of the disease are considered to be traumatic injuries, invasive medical manipulations against the background of genetic predisposition.Aim. Invite attention of general practitioners and pediatricians to a rare disease, namely progressive ossifying fibrodysplasia in children and the peculiarities of its diagnosis.Results. The article presents a clinical case of progressive ossifying fibrodysplasia (Munchmeyer's disease) in a 4-year-old girl. At birth, the child was diagnosed with a foot deformity characteristic of this pathology (shortening of the first metatarsal finger, flexion-rotation contracture of both feet). The clinic of the disease manifested itself at the age of 3 years, when, after falling on the back, a dense formation was noticed in the area of the left shoulder blade. Half a year after the fall, swelling and pain appeared in the sacro-coccygeal region of the spine. The girl was consulted by an orthopedist, dermatologist, and oncologist. During the examination of the child, characteristic clinical features of progressive ossifying fibrodysplasia were revealed, namely, deformation and fixed position of the chest, tense neck muscles, sharp limitation of movements in all parts of the spine, limitation of bending in the left elbow joint, clinodactyly, valgus deformity of the big toes. During the ultrasound examination, the following changes were diagnosed: swelling of muscle tissue in the neck area, subscapular area on the left and sacrococcygeal joint; multiple hypoechoic formations of irregular shape, heterogeneous echo structure with hyperechoic inclusions with an acoustic shadow; a focal change in the muscle structure in the form of a loss of the characteristic pinnate structure of the perimysium. The diagnosis was confirmed histologically. No characteristic changes were found in clinical and biochemical studies. The girl is under supervision. No worsening of the child's condition has been recorded over the past four years.
Améliorer l’accès aux soins palliatifs pour les personnes confrontées à des iniquités socioéconomiques : conclusions d’une étude pilote de recherche communautaire
Authors: Santos Salas Anna , Bablitz Cara , Morris Heather , Vaughn Lisa , Bardales Olga , Easaw Jennifer , Wildeman Tracy , Duggleby Wendy , Salami Bukola , Watanabe Sharon M.
Published: August 2023

Introduction

Au Canada, les personnes confrontées à des iniquités socioéconomiques présentent des taux supérieurs de diagnostics tardifs et des taux inférieurs de survie par rapport à la population générale. Peu de services de soins palliatifs sont destinés à ces personnes en particulier. Nous avons mis au point une intervention infirmière en milieu communautaire et en contexte urbain au Canada afin d’améliorer l’accès aux soins palliatifs pour les personnes confrontées à des iniquités socioéconomiques et atteintes d’une maladie limitant leur espérance de vie.

Méthodologie

Cette étude de recherche qualitative communautaire combine des méthodes de recherche critiques et participatives. Elle a été réalisée en partenariat avec l’équipe PCOAT (Palliative Care Outreach Advocacy Team), basée à Edmonton (Alberta), qui offre des services de proximité aux populations désavantagées sur le plan socioéconomique ayant besoin de soins palliatifs. Après une phase exploratoire nous ayant permis de définir l’intervention, nous avons mis en oeuvre une phase pilote d’un an, durant laquelle une infirmière s’est jointe à l’équipe PCOAT. Cette infirmière a eu pour tâche d’établir des liens de confiance, de coordonner les soins complexes et de répondre aux besoins à la fois en matière de santé et sur le plan pratique. Vingt-cinq participants ont pris part à cette intervention. Ils ont été interviewés chacun au moins une fois afin de décrire leurs expériences en lien avec l’intervention. Nous avons ensuite effectué une analyse thématique des données.

Résultats

La plupart des participants étaient des hommes, étaient autochtones et étaient atteints d’un cancer à un stade avancé. Les participants avaient d’importantes difficultés financières, se trouvaient ou s’étaient déjà trouvés en situation de logement précaire et avaient précédemment connu de sérieuses difficultés d’accès à des soins de santé. Ils ont décrit leurs besoins sur le plan social et sur le plan de la santé, en matière notamment de logement, de finances, de transport, de soulagement des symptômes, de réduction des méfaits et de soins de fin de vie. Ils ont également déclaré que leur accès aux services sociaux et de santé s’était amélioré et se sont dits satisfaits de l’intervention liée à l’étude.

Conclusion

D’après les données recueillies, l’intervention liée à l’étude semble avoir favorisé un meilleur accès aux soins palliatifs, de meilleures expériences pour les participants et une prestation de soins plus équitable.
Determining of Some Engineering Properties for Harvest and Post Harvest Applications of Two Common Cultivated Hazelnuts Cultivars in Türkiye
Authors: ERSOY Hamide , ALTUNTAŞ Ebubekir
Published: August 2023

In this study, some engineering characteristics (physical properties, colour characteristics, coefficients of static friction and mechanical behaviours) of the shelled and kernel of Çakıldak and Foşa hazelnut cultivars cultivated in Türkiye were investigated for harvest and post harvest applications. The moisture contents of Çakıldak and Foşa cultivars for shelled hazelnut 8.69-7.56% (% wet basis) and kernel hazelnut 5.37- 4.64% (% wet basis), respectively. Statistically significant (p
The Role of Storage Duration and Conditions on the Survival and Pathogenicity of Entomopathogenic Nematodes
Authors: AKI Onur , YÜKSEL Ebubekir , İMREN Mustafa , BOZBUĞA Refik , CANHİLAL Ramazan
Published: August 2023

Entomopathogenic nematodes (EPNs) (Rhabditida: Heterorhabditidae and Steinernematidae) are effective biocontrol agents for many insect pests and are generally stored for a period of time prior to their use in the laboratory or field. However, unfavorable storage conditions have a great impact on the survival and infectivity of EPNs. This study was conducted to determine the optimum storage conditions of infective juveniles (IJs) of four native EPN species (Heterorhabditis bacteriophora FLH-4H, H. indica 216-H, Steinernema feltiae KCS-S, and S. bicornotum MGZ-4S) under laboratory conditions. The survival capability of the IJs was tested at different concentrations (500, 1000, 1500, and 2000 IJs), temperatures (9 and 25 °C) and storage media [double-distilled water (ddH2O), tap water, and sterile Ringer solution]. In general, the survival of IJs of tested EPN species was the highest at the 1st month after treatment (MAT) at the concentrations of 1000 and 1500 IJs and gradually decreased with the increasing storage periods. The survival rates of the IJs of Steirnematids were generally higher than Heterorhabditid species. The highest survival of IJs was generally obtained after 1-month storage in Ringer solution at 9°C while tap water led to poor survival for the IJs at both temperatures tested. The IJs that were stored at 9°C induced higher mortalities on the larvae of Galleria mellonella (L.) (Lepidoptera: Pyralidae). The results showed that the IJs of tested EPN species can remain viable for a longer period of time in Ringer solution at 1000 and 1500 IJs concentrations at 9°C without losing much of their infectivity.
La Evaluación en la Educación Física: una problemática de la Educación Contemporánea
Authors: Llapur Eduardo David
Published: August 2023

El presente trabajo pone en cuestión un aspecto trascendental de la educación y de la cual nuestra disciplina, la Educación Física (en adelante EF), no logra incorporar y definir en forma clara y precisa: la evaluación . Para ello, se analizarán, desde una primera instancia a la evaluación como una problemática de la educación en general, para luego introducirnos en nuestra disciplina; a los paradigmas que prevalecieron, y prevalecen en nuestras prácticas, y las concepciones que subyacen bajo de estas, las cuales entienden al cuerpo y al movimiento como algo natural y dado, y el método "evaluativo" cuantitativo como el más usado para ello. Intentando demostrar como esta postura no solo obstaculiza y torna inefectiva el proceso de otorgar un juicio de valor en las clases, sino también el de toda nuestra práctica diaria, lo cual denota de un cambio urgente.
Tecnologias de sexo/gênero na Ginástica Artística: o processo de diferenciação sexual das argolas, barras assimétricas e mesa salto
Authors: Passos Adriano Martins Rodrigues dos , Quitzau Evelise Amgarten
Published: August 2023

Este artigo analisa o desenvolvimento da ginástica artística e das tecnologias de sexo/gênero que instituem, operam e sustentam a bicategorização dos seus aparelhos e eventos. Para tanto, pensamos essa modalidade como um dos elementos do dispositivo do esporte, cujo funcionamento é interdependente e complementar ao dispositivo sexo/gênero. Mediante pesquisas bibliográficas e um recorte histórico que começa na segunda metade do século XIX até o Código de Pontuação 2017-2020, buscamos evidenciar e problematizar o processo de diferenciação de três aparelhos/eventos da ginástica artística: argolas, estritamente para homens; barras assimétricas, criadas para mulheres; e mesa de salto, comum para mulheres e homens. Como resultado, constatamos que a diferenciação dos aparelhos, baseada no sexo/gênero do/da praticante, reflete e responde às necessidades de manutenção do ordenamento social do sexo/gênero e da divisão sexual do trabalho de cada momento histórico, operando, desse modo, como instrumento que normaliza e normatiza o sexo/gênero, as expressões de feminilidades e masculinidades e o caráter arbitrário e compulsório da separação de homens e mulheres nas competições esportivas.
Impactos del Sistema Tributario en el modelo de descuento de flujos de fondos
Authors: Milanesi Gaston Silverio , Tennina Maria Agustina
Published: August 2023

La determinación del valor de los ahorros fiscales y el impacto del impuesto a la renta en la valuación de empresa depende del sistema tributario vigente en el mercado. Los efectos fiscales que implican pagos y ahorros deben analizarse con el sistema tributario donde opera la firma. Los trabajos de Modigliani y Miller (1963) y Miller (1977) suponen un sistema clásico de imposición a la renta. La Organización Mundial del Comercio (OCDE) identifica siete sistemas tributarios clasificados en dos grandes grupos: integrados y clásicos.  El trabajo revisa los modelos existentes, particularmente el Modelo General. Seguidamente, expone las ecuaciones de valor correspondientes a los diferentes sistemas tributarios. Mediante un análisis de casos se analiza el impacto en las variables del sistema tributario en el que opera la firma, según los sistemas clasificados por la OCDE.