bluuebunny/crossref_metadata_2025 huggingface dataset:
Ovicidal Effect of Entomopathogenic Fungi on Emerald Ash Borer, Agrilus planipennis Fairmaire, Eggs
Authors: Simeto Sofía , Held Benjamin W. , Showalter David N. , Bushley Kathryn E. , Blanchette Robert A.
Published: December 2024

The emerald ash borer (EAB) is an invasive beetle that has killed hundreds of millions of ash trees throughout North America since its arrival. The use of entomopathogenic fungi as part of integrated pest management approaches is considered effective against a wide range of insect pests. The aim of this study was to screen and select locally adapted EAB-associated entomopathogenic fungi with ovicidal effect on EAB eggs under laboratory conditions. The pathogenicity of nine fungal strains, previously isolated from EAB galleries, and the commercial Beauveria bassiana strain GHA was tested. Three of these, Akanthomyces muscarius 48-27, Lecanicillium longisporum 66-14 Lecanicillium psalliotae 59-2, and GHA B. bassiana strain consistently showed significant ovicidal effects and a high percentage of inoculum recovery both from eggs and neonate larvae. The high levels of inoculum recovery from neonate larvae demonstrate that, even after emergence, larvae were infected. The possibility of disrupting EAB’s life cycle at the egg stage through microbial control represents a potential management opportunity that should be explored in future field studies. Future work should also study the effect of EPF on neonate larvae survival and performance. To our knowledge, this is the first study to evaluate the effect of entomopathogenic fungi against the egg stage of EAB.
Generative AI in Medicine and Healthcare: Moving Beyond the ‘Peak of Inflated Expectations’
Authors: Zhang Peng , Shi Jiayu , Kamel Boulos Maged N.
Published: December 2024

The rapid development of specific-purpose Large Language Models (LLMs), such as Med-PaLM, MEDITRON-70B, and Med-Gemini, has significantly impacted healthcare, offering unprecedented capabilities in clinical decision support, diagnostics, and personalized health monitoring. This paper reviews the advancements in medicine-specific LLMs, the integration of Retrieval-Augmented Generation (RAG) and prompt engineering, and their applications in improving diagnostic accuracy and educational utility. Despite the potential, these technologies present challenges, including bias, hallucinations, and the need for robust safety protocols. The paper also discusses the regulatory and ethical considerations necessary for integrating these models into mainstream healthcare. By examining current studies and developments, this paper aims to provide a comprehensive overview of the state of LLMs in medicine and highlight the future directions for research and application. The study concludes that while LLMs hold immense potential, their safe and effective integration into clinical practice requires rigorous testing, ongoing evaluation, and continuous collaboration among stakeholders.
Gaia-X-Med: Experiences with Building Dataspaces for Medical Applications
Authors: Gerlach Bennet , Hesse Hannes , Fischer Stefan , Leucker Martin
Published: December 2024

Gaia-X, a European initiative, aims to create a digital sovereignty framework for service ecosystems in the future Internet. Its applicability to the health domain was explored in the Gaia-X-Med project, which aimed to establish a common dataspace for various medical use cases based on Gaia-X principles. This paper presents a trust- and consent-based approach to the secure authentication and digital contract negotiation central to this endeavor and discusses the challenges that arose during the adoption of the Gaia-X framework, particularly relating to the strict requirements of the European healthcare domain with regards to privacy and consent regulations. By exploring the practical implications of Gaia-X in the healthcare context, this paper aims to contribute to the ongoing discussions surrounding the digital sovereignty of both citizens and corporations, as well as its realization via future Internet technologies.
Predicting the Tensile Properties of Carbon FRCM Using a LASSO Model
Authors: Rodríguez-Marcos María , Villanueva-Llaurado Paula , Fernández-Gómez Jaime , Abellán-García Joaquín , Sisa-Camargo Augusto
Published: December 2024

The use of Fibre Reinforced Cementitious Matrix (FRCM) for structural retrofitting requires prior assessment of the composite’s mechanical properties, particularly its tensile stress–strain response. This paper presents a LASSO regression model applied to 107 uniaxial tensile tests on Carbon FRCM in order to investigate the impact of both the material and testing parameters on FRCM performance. A highly effective LASSO regression model was trained using k-fold validation, resulting in concise and comprehensible models. Within the testing parameters, both the gripping system and load–speed ratio significantly affected the performance. A substantial impact on ultimate values was found for the load–speed ratio. From the material-related parameters, the most influential was the textile coating in terms of strength and the existence of bilinear or trilinear behaviour. It was also concluded that the combination of textile and matrix properties influenced the stress–strain response at all stages, with high-performance mortars resulting in better textile-to-matrix interaction.
Synthesis and Perspectives on Disturbance Interactions, and Forest Fire Risk and Fire Severity in Central Europe
Authors: Leonardos Leonardos , Gnilke Anne , Sanders Tanja G. M. , Shatto Christopher , Stadelmann Catrin , Beierkuhnlein Carl , Jentsch Anke
Published: December 2024

Wildfire risk increases following non-fire disturbance events, but this relationship is not always linear or cumulative, and previous studies are not consistent in differentiating between disturbance loops versus cascades. Previous research on disturbance interactions and their influence on forest fires has primarily focused on fire-prone regions, such as North America, Australia, and Southern Europe. In contrast, less is known about these dynamics in Central Europe, where wildfire risk and hazard are increasing. In recent years, forest disturbances, particularly windthrow, insect outbreaks, and drought, have become more frequent in Central Europe. At the same time, climate change is influencing fire weather conditions that further intensify forest fire dynamics. Here, we synthesize findings from the recent literature on disturbance interactions in Central Europe with the aim to identify disturbance-driven processes that influence the regional fire regime. We propose a conceptual framework of interacting disturbances that can be used in wildfire risk assessments and beyond. In addition, we identify knowledge gaps and make suggestions for future research regarding disturbance interactions and their implications for wildfire activity. Our findings indicate that fire risk in the temperate forests of Central Europe is increasing and that non-fire disturbances and their interactions modify fuel properties that subsequently influence wildfire dynamics in multiple ways.
Dietary Iodine Can Effectively Alleviate the Adverse Effects of Fermented Rapeseed Meal on the Growth, Liver Health, and Antioxidant Capacity of Tilapia (GIFT, Oreochromis niloticus)
Authors: Peng Di , Li Ya-Xue , Dong Li-Xue , Cheng Ke , Wen Hua , Tian Juan , Zhang Jian-Min , Liu Yang-Yang , Gao Wei-Hua , Min Yong , Liu Ming-Dian , Jiang Ming
Published: December 2024

An 8-week feeding trial was conducted to evaluate the effects of dietary fermented rapeseed meal (FRM), potassium iodide, and their interactions on growth performance, approximate composition, and antioxidant capacity in tilapia, Oreochromis niloticus (initial body weight: 3.50 ± 0.15 g). Six isonitrogenous and isolipidic diets from a 2 × 3 factorial design were formulated with two levels of FRM (25.8 and 51.6%) and three levels of potassium iodide (0, 6, and 12 mg/kg), respectively. The results indicated that dietary levels of FRM and iodine had no significant influence on the SR of tilapia but exerted significant effects on weight gain (WG), specific growth rate (SGR), feed intake (FI), hepatosomatic index, and viscerosomatic index. The WG, SGR, and FI of tilapia in the 51.6% FRM groups were significantly lower than those in other groups (p < 0.05), and iodine inclusion in the 51.6% FRM diet significantly enhanced WG, SGR, and FI of tilapia (p < 0.05). Dietary iodine significantly increased the whole-body and muscle lipid content in the tilapia (p < 0.05). The content of total bilirubin (T-Bil) and the activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the tilapia serum were significantly reduced by the inclusion of 6–12 mg/kg iodine in 51.6% FRM level (p < 0.05), and the serum total triiodothyronine content was significantly elevated by the supplementation of 12 mg/kg iodine (p < 0.05). Significant interactions between dietary FRM and iodine were found in serum T-Bil content and triglyceride and AST activity (p < 0.05). Dietary supplementation of iodine in high FRM diets (51.6%) significantly increased the activities of total superoxide dismutase (T-SOD), catalase (CAT), and total antioxidant capacity (T-AOC) and decreased the content of malondialdehyde (MDA) in the liver of tilapia (p < 0.05). The activity of T-SOD, CAT, and T-AOC and the content of MDA in the liver of tilapia significantly interacted with the levels of dietary FRM and iodine (p < 0.05). Furthermore, the liver cell structure was further ameliorated, and the liver health status was significantly enhanced in each iodine treatment group.
Interaction of the Shock Train Leading Edge and Filamentary Plasma in a Supersonic Duct
Authors: Hahn Loren C. , Lax Philip A. , Morris Scott C. , Leonov Sergey B.
Published: December 2024

Quasi-direct current (Q-DC) filamentary electrical discharges are used to control the shock train in a back-pressured Mach 2 duct flow. The coupled interaction between the plasma filaments and the shock train leading edge (STLE) is studied for a variety of boundary conditions. Electrical parameters associated with the discharge are recorded during actuation, demonstrating a close correlation between the STLE position and dynamics. High-speed self-aligned focusing schlieren (SAFS) and high frame-rate color camera imaging are the primary optical diagnostics used to study the flowfield and plasma morphology. Shock tracking and plasma characterization algorithms are employed to extract time-resolved quantitative data during shock–plasma interactions. Four distinct shock–plasma interaction types are identified and outlined, revealing a strong dependence on the spacing between the uncontrolled STLE and discharge electrodes and a moderate dependence on flow parameters.
The Role of Light in Enhancing the Nutritional and Antioxidant Qualities of Basil, Mint and Lemon Balm
Authors: Jakubczyk Karolina , Szymczykowska Kinga , Melkis Klaudia , Maciejewska-Markiewicz Dominika , Nowak Anna , Muzykiewicz-Szymańska Anna , Skonieczna-Żydecka Karolina
Published: December 2024

Mint (Mentha L.), basil, (Ocimum basilicum) and Melissa (Melissa officinalis L.) are herbaceous plants from the Lamiaceae family. They have a wide range of health benefits and flavour properties which are highly valued around the world. Alternative methods of growing plants to minimise greenhouse gas emissions during autumn and winter are being sought in the face of increasing climate change. One way to achieve this is to switch from HPS to LED lighting. LED lighting has a longer lifespan and higher efficiency while using less energy and better matching the colour of the light to the needs of the herbs. This study tested the hypothesis that the type of illumination (solar, HPS, and LED) significantly impacts the antioxidant and nutritional qualities of herbs. The results indicated that LED lighting enhanced biochemical properties, supporting its adoption for sustainable plant cultivation.
Analysis of Taste Quality Differences Between High and Low Grades of Ninghong Tea: From the Perspective of Sensory, Metabolite, and Taste Activity Values
Authors: Yue Cuinan , Wang Zhihui , Peng Hua , Jiang Lianghui , Yang Puxiang , Li Wenjin
Published: December 2024

In this study, the taste quality difference between high (Ninghong-Jinhao tea, JH, unfolded fresh leaves) and low (Ninghong-Congou tea, CG, unfurled fresh leaves) grades of Ninghong tea (unique black tea) was analyzed from the perspective of sensory omics, non-targeted metabolomics, and chemical dose. JH was characterized by sweetness and mellowness with umami, while CG was characterized by sweetness and thickness. A total of 94 differential metabolites contribute to the quality difference between two grades. Further quantitative analysis revealed that JH exhibited a high accumulation of amino acids, catechins, and theaflavins, while CG demonstrated a high accumulation of water extract, tea polyphenols, flavonol glycosides, and saccharides. Taste activity values (TAVs) analysis revealed that the key taste components of JH and CG were catechin, epigallocatechin gallate, three theaflavins, caffeine, myrictin-3-O-glucoside, quercetin-3-O-rutinoside, quercetin-3-O-glucoside, quercetin-3-O-galactoside, kaempferol-3-O-rutinoside, kaempferol-3-O-glucoside, and gallic acid. Among the identified compounds, the TAVs of five flavonol glycosides in Ninghong tea were found to be greater than 10 for the first time. This study is helpful to understand the taste quality difference between different grades of Ninghong tea from the molecular sensory level, providing a scientific foundation for quality improvement and targeted regulation.
Technology Development in Online Grocery Shopping—From Shopping Services to Virtual Reality, Metaverse, and Smart Devices: A Review
Authors: Stecuła Kinga , Wolniak Radosław , Aydın Barış
Published: December 2024

This paper presents a review of the technologies and services associated with online grocery shopping. The progress in the field of online grocery shopping has been very rapid in recent years. Hence, there was a need to systematize knowledge about the latest various solutions used in this topic. The authors searched the internet, focusing on websites of different supermarkets, shops, and other services that offer online shopping, as well as reviewed scientific papers. Based on the collected material, the authors created four thematic parts, which include: (1) supermarket services; (2) dedicated grocery delivery services and farm-to-table; (3) shopping in Virtual Reality and the metaverse; smart devices and (4) AI in food ordering—the last part includes smart devices, such as smart refrigerators, ovens, their functionality, and the services connected with them. The authors refer to 243 sources. The research includes the three following objectives: (1) exploring and presenting the emerging applied ways of online grocery shopping, (2) exploring and presenting the latest technological advances related to the digitalization of grocery shopping, (3) discussing the upcoming technologies, services, and methods in online grocery shopping. This paper provides knowledge about a wide range of solutions offered by both supermarkets and stores (e.g., shopping applications, VR applications, metaverse shopping) and other companies (e.g., deliveries, product tracking), highlighting the numerous functions available thanks to smart devices (e.g., voice control, own shopping lists, control of products, their quantities and expiration dates, management of user preferences, and many more). This paper also discusses social issues related to the presented solutions, such as their influence on consumer behavior, barriers to adoption, and the associated challenges.
Lifestyle Habits and Nutritional Profile of the Spanish Population: A Comparison Between the Period During and After the COVID-19 Pandemic
Authors: Sandri Elena , Werner Lisa Ursula , Bernalte Martí Vicente
Published: December 2024

The aim of this study was to investigate the changes in habits regarding the health and lifestyle of the Spanish population during and after the COVID-19 pandemic. A cross-sectional design was used. Data were collected during the pandemic from 22,181 participants and after the pandemic from 3907 participants using the NutSo-HH Scale, assessing demographic, nutritional, and lifestyle variables. Key findings reveal a slight increase in exercise duration (+6.61%) post-pandemic, along with reductions in fried food (−3.57%), juice (−6.45%), and alcohol consumption (−9.66%). Conversely, there were notable increases in the consumption of ultra-processed foods (+2.16%), soft drinks (+6.47%), and coffee/energy drinks (+38.95%). Sleep quality, body image, and self-perceived health showed minor declines. These findings indicate that despite some positive behavioral changes, there is still a significant dependence on unhealthy dietary choices, negatively impacting both mental and physical health. The results highlight the need for public health strategies which encourage healthier eating, increased physical activity, and better sleep quality to reduce the long-term effects of lifestyle changes brought on by the pandemic. Focused interventions are necessary to curb the rising consumption of ultra-processed foods and sugary beverages while fostering overall well-being. This study underscores the vital role of ongoing surveillance and customized public health initiatives to enhance general health in the post-pandemic era.
Fabrication and Encapsulation of Soy Peptide Nanoparticles Using Ultrasound Followed by Spray Drying
Authors: Jiang Yiqun , Luo Zhen , Xiang Fenglan , Liu Yubin , Yan Jin , Wang Jinmei
Published: December 2024

Peptide aggregation inevitably occurs during hydrolysis, and insoluble peptide aggregates (ISPA) are used as feed for animals due to their poor water solubility and unpleasant bitter flavor. Ultrasound was used to fabricate soy peptide nanoparticles by reassembling ISPA, followed by spray-drying encapsulation to develop low-bitterness peptide microcapsules with soluble soybean polysaccharide (SSPS) and stevioside (STE) as wall materials. Powder properties, bitter taste, and the morphology of the microcapsules were evaluated. The formation of soluble peptide nanoparticles (<200 nm) was observed after ultrasound due to the reassembly of ISPA through the disruption of non-covalent intermolecular interactions. A gradual reduction in bitter taste was observed with increasing ultrasonic time. Moreover, spray-drying encapsulation with STE could effectively improve the flowability and wettability of the microcapsule powder owing to the rapid migration of surface-active STE to the atomized droplet surface, as evidenced by the lower angle of repose and wettability time. Peptide microcapsules with STE (spherical particles with smooth surfaces) exhibited lower density and reduced bitterness because STE (0–0.1%, w/w) exhibited an excellent bitter-masking effect. With high STE concentrations (>0.5%, w/w), microcapsules exhibited a higher bitter taste than unencapsulated peptides due to the increased surface distribution of STE on the microcapsules. These results provide an effective technique to improve the physicochemical properties of ISPA.
A Note on Exact Results for Burgers-like Equations Involving Laguerre Derivatives
Authors: Garra Roberto , Dattoli Giuseppe , Droghei Riccardo
Published: December 2024

In this work, we consider some Burgers-like equations involving Laguerre derivatives and demonstrate that it is possible to construct specific exact solutions using separation of variables. We prove that a general scheme exists for constructing exact solutions for these Burgers-like equations and extending to more general cases, including nonlinear time-fractional equations. Exact solutions can also be obtained for KDV-like equations involving Laguerre derivatives. We finally consider a particular class of Burgers equations with variable coefficients whose solutions can be obtained similarly.
Characterization of the Mitochondrial Genome of Cambaroides schrenckii (Astacidea: Cambaridae) and Its Phylogenetic Implications
Authors: Liu Xuewei , Li Ben , Yang Yan , Zhang Jun , Hu Chunbo , Zhang Yuxi , Zhou Jiawang , Liu Yinlong , Qiu Hongyu , Wang Chunren , Gao Junfeng
Published: December 2024

Background: Cambaroides schrenckii is an endangered freshwater crayfish in China, belonging to the genus Cambaroides, that can act as a complementary host for paragonimus. The objective of this study was to examine the complete mitochondrial genome characteristics and their evolutionary relationships within the Astacidea. Methods: The analysis of gene rearrangements and evolutionary relationships was conducted through the sequencing of the mitochondrial genome of C. schrenckii. Results: C. schrenckii mitochondrial genome length was 15,572, comprising thirteen PCGs, two rRNAs, 22 tRNAs, and one d-loop region of C. schrenckii. The mitochondrial genome of C. schrenckii exhibits an A + T content of 69.61% and a G + C content of 30.39%. Among the thirteen PCGs, cytb, nad3, and nad6 have a start codon of ATT, while the other ten PCGs have ATC, ATA, and ATG start codons. All 22 tRNA genes displayed a typical cloverleaf secondary structure. Gene rearrangement analysis showed that seven gene arrangements were identified based on PCGs in the infraorder Astacidea, with type I being the most common. Conclusions: The relationship between the American Cambaridae is closer to Astacidae than the Asian Cambaridae. The present study provides a theoretical basis for further discussions of developmental relationships in the infraorder Astacidea.
Polygenic Risk Score Implementation into Clinical Practice for Primary Prevention of Cardiometabolic Disease
Authors: Hughes Julia , Shymka Mikayla , Ng Trevor , Phulka Jobanjit S. , Safabakhsh Sina , Laksman Zachary
Published: December 2024

Background: Cardiovascular disease is a leading cause of mortality globally and a major contributor to disability. Traditional risk factors, as initially established in the FRAMINGHAM study, have helped to stratify populations and identify patients for early intervention. Incorporating genetic factors enhances risk stratification tools, enabling the earlier identification of individuals at increased risk and facilitating more targeted and effective risk factor modifications. While monogenic risk variants are present in a minority of the population, polygenic risk scores (PRS) are collections of multiple single-nucleotide variants that collectively provide summative risk and capture a more accurate risk score for a greater number of people. PRS have demonstrated clear utility in cardiometabolic diseases by predicting onset, progression, and therapeutic response. Methods: A structured and exploratory hybrid search strategy was employed, combining keyword-based database searches and supplementary techniques to comprehensively synthesize the literature on PRS implementation in clinical practice. Discussion: A comprehensive overview of PRS in cardiometabolic diseases and their potential avenues for integration into primary care is discussed. First, we examine the implementation of genetic screening, risk communication, and intervention strategies through the lens of the American Heart Association’s implementation criteria, focusing on their efficacy, minimization of harm, and logistical considerations. Then, we explores how the varied perceptions of patients and practitioners towards PRS can influence both adoption and utilization. Lastly, we addresses the need for the development of clear guidelines and regulations to support this process, ensuring PRS integration is both scientifically sound and ethically responsible. Future directions: Initiatives aimed at advancing personalized approaches to disease prevention will enhance health outcomes. Developing guidelines for the responsible use of PRS by establishing benefits, while mitigating risk, will a key factor in implementation for clinical utility. Conclusions: For integration into clinical practice, we must address both patient and provider concerns and experience. Standardized guidelines and training will help to effectively implement PRS into clinical practice. Developing these resources will be essential for PRS to fulfill its potential in personalized, patient-centered care.
Nurses’ Clinical Practice in Nursing Homes: Depressive Symptoms and Fall Risk Assessment
Authors: Queirós Alcina Matos , von Gunten Armin , Martins Maria Manuela , Verloo Henk
Published: December 2024

Background: Depression and falls are highly prevalent, interrelated concerns for nursing home (NH) residents. Relationships between depression and falls should guide nurses towards developing evidence-based practices for assessing these conditions together. This study aimed to ascertain NH nurses’ clinical practices and perceptions regarding the assessment of depression and fall risk. Methods: This study was an exploratory descriptive study on the reported practices and perceptions from NH nurses in the canton of Vaud, Western Switzerland. Statistical analyses included descriptive statistics, nonparametric tests and a content analysis of responses to open-ended questions. Results: The mean age of our 116 responding nurses was 44.6 years old (SD = 11.3), 99 were women and their mean work experience in NHs was 13.1 years (SD = 9.2). The reporting showed that 88.8% of nurses relied on mood observation for assessing depression and 88.8% relied on the history of falls to identify fall risk. Only 75.9% and 61.2% of nurses used validated scales to detect depression and fall risk, respectively. Additionally, 56.9% of participants considered depression to be a significant factor in fall risk. Conclusion: Validated tools to assess depression and fall risk in NHs should be used more widely. Health policies must support and enhance NH nurses’ training and skills.
Differences in Psychological Coping with Illness During the Treatment and Survivorship Phases in Adolescents According to Age and Sex
Authors: Sáez-Rodríguez Diego-José , Ortigosa-Quiles Juan-Manuel , Riquelme-Marin Antonio , Suriá-Martínez Raquel , Chico-Sánchez Pablo
Published: December 2024

Introduction: Despite the importance of addressing different stages of cancer, there is a lack of data on how these stages relate to coping strategies. This study aims to analyze coping strategies among adolescents with cancer by comparing two distinct time points, the treatment phase and the post-treatment phase, with a particular focus on age and gender. Methodology: A total of 201 cancer patients aged 12 to 17 years from Alicante, Valencia, and Madrid participated in the study. They completed a Demographic and Clinical Data Form questionnaire capturing age, gender, and illness phase, along with the ACS to assess coping strategies. Results: During the treatment phase, strategies such as “worrying”, “stress reduction”, “ignoring the problem”, and “self-blame” were used more frequently than during the follow-up phase, revealing notable changes in emotional management between the two stages. Gender differences were observed in the first three strategies. Conclusions: The coping strategies of adolescents with cancer vary significantly between the treatment and follow-up phases, with greater use of certain strategies during treatment and a decline in their use post-treatment. These findings highlight the evolving emotional demands of each stage and emphasize the need for targeted interventions that address the specific coping needs unique to each phase. Such targeted interventions in clinical settings could support emotional management by adapting strategies to the distinct challenges faced by adolescents during treatment and post-treatment phases.
Prevalence of Urinary Incontinence in Female Professional Soccer Players by Category and Specific Position: A Comparative Study with a Control Group
Authors: Sebastian-Rico Julia M. , Muñoz-Fernández María Jesús , Martínez-Aranda Luis Manuel , Calvo-Lluch África , Ortega-Becerra Manuel
Published: December 2024

Background/Objectives: Urinary incontinence (UI) significantly impacts quality of life, with varying prevalence in women depending on factors such as age, childbirth, and type of sport practiced. This study compared the prevalence, types, and severity of urinary incontinence (UI) between professional female soccer players and sedentary students, analyzing its relation to playing position and competitive level. Methods: A descriptive, observational, and analytical cross-sectional study was conducted, assessing the prevalence, severity, and types of UI among 235 nulliparous professional female soccer players (experimental group, EG) and 252 sedentary female students (control group, CG). Data were collected using the short version of the International Consultation on Incontinence Questionnaire (ICIQ-SF). Statistical analyses included Fisher’s exact test to compare prevalence rates. Results: The findings revealed that 35% of soccer players and 31% of sedentary students reported experiencing UI. Stress urinary incontinence (SUI) was the most prevalent type in both groups, affecting 26% of soccer players and 14% of sedentary students, while mixed UI was more frequent among sedentary women (17%) (p < 0.05). No significant differences were observed in UI prevalence based on playing position or competitive level (p ≥ 0.05). However, female soccer players exhibited a significantly higher prevalence of UI during physical exertion or exercise compared to the control group (p ≤ 0.001), suggesting that high-impact sports may contribute to pelvic floor dysfunction. Additionally, 23.8% of soccer players reported mild-to-moderate UI severity. Conclusion: Female soccer players showed higher UI prevalence during exercise, underscoring the need for targeted interventions like pelvic floor training.
The Role of the MeToo Route in Improving the Health of Gender-Based Violence and Isolating Gender Violence Survivors
Authors: Cañaveras Paula , Burgués-Freitas Ana , Joanpere Mar
Published: December 2024

Background/Objectives: The scientific literature has provided evidence on the negative health effects experienced by those who suffer gender-based violence (GBV) and isolating gender violence (IGV), the latter being a form of retaliation against those who support GBV victims. However, less attention has been paid to the potential health improvements following the initial support received by victims. Methods: This study examines the positive health outcomes among survivors of GBV and IGV after they engaged with the “MeToo route,” an initiative of the MeToo movement aimed at raising awareness about gender violence and fostering solidarity through support networks that traveled through 13 Spanish universities through more than 20 events in September 2022. Results: Using communicative methodology, survivors shared how their health, previously harmed by their experiences of violence, improved as a result of the support provided after knowing the MeToo support network. Conclusions: The findings highlight the crucial role of solidarity networks in alleviating the health impacts of GBV and IGV and underscore the importance of effective support systems for recovery.
Polish Firefighters’ Participation in Interventions Related to Behavioral Disorders in the 2020–2022 Period: An Observation of Incidents
Authors: Dudzinski Lukasz , Czyzewski Lukasz , Gałazkowski Robert , Jaskiewicz Filip , Nadolny Klaudiusz , Kubiak Tomasz
Published: December 2024

Background: Rescue service interventions for patients with behavioral disorders are quite common. The aim of this study is to analyze interventions of Polish State Fire Service units in incidents involving health threats to victims with behavioral disorders. Materials and Methods: This study used data from the Decision Support System of the State Fire Service. Events in the period of 1 January 2020 at 00.00–31 December 2022 at 23:59 were used for analysis. Results: In the 2020–2022 period, firefighters were dispatched 321 times to interventions concerning injured individuals with behavioral disorders. Isolated emergency medical incidents most often concerned mental disorders (23%) and least often concerned suicide attempts (8%) (p = 0.033). It was shown that the duration of the intervention (emergency care time) was significantly longer in the case of interventions related to the autumn period (p < 0.001). Conclusions: Our results describe parameters associated with behavioral health responses within the Polish fire service.
The Impact of Mood Disorders on Adherence, on Life Satisfaction and Acceptance of Illness—Cross-Sectional Observational Study
Authors: Jeżuchowska Alicja , Cybulska Anna Maria , Rachubińska Kamila , Skonieczna-Żydecka Karolina , Reginia Artur , Panczyk Mariusz , Ćwiek Dorota , Grochans Elżbieta , Schneider-Matyka Daria
Published: December 2024

Background: Mood disorders are among the most prevalent and debilitating mental conditions in worldwide populations. The aim of this study was to identify the factors influencing life satisfaction, disease acceptance, and therapeutic adherence among people with mood disorders. Methods: This survey-based study included 103 people with mood disorders. It was performed using the author questionnaire, and standardized research tools, namely the Adherence to Refills and Medication Scale (ARMS), the Acceptance of Illness Scale (AIS), the Beck Depression Inventory (BDI), and the Satisfaction with Life Scale (SWLS). Results: The level of life satisfaction decreased with the increase in the severity of the depressive symptoms (SE = −0.665, p < 0.001). Mood disorder patients with more severe depressive symptoms had significantly higher scores on the adherence scale (SE = 0.290, p = 0.003). The patients with higher levels of depressive symptoms showed a lower level of acceptance of the disease. Conclusions: 1. The dosage of medications taken, and the severity of the depressive symptoms determine life satisfaction of people with mood disorders. 2. The respondents with a greater severity of depressive symptoms scored higher on the adherence scale, which means that they were more likely to be non-adherent to the treatment recommendations. The type of mood disorder may affect patient adherence. The subjects with bipolar disorder showed higher adherence and those with anxiety–depressive disorder showed a lower adherence than the patients with depression. 3. The subjects with more severe depressive symptoms showed a lower degree of acceptance of the disease.
Impact of a Clinical Decision Support System on the Efficiency and Effectiveness of Performing Medication Reviews in Community Pharmacies: A Randomized Controlled Trial
Authors: Dabidian Armin , Kinny Florian , Steichert Melina , Schlottau Sabina , Bartel Anke , Schwender Holger , Laeer Stephanie
Published: December 2024

Background: Clinical decision support systems (CDSSs) already support community pharmacists in conducting medication reviews (MRs) by identifying important information on interactions and suggesting clinical solutions. However, their impact in terms of quality and time savings is widely unexplored. The aim of our study was to investigate whether MRs are performed faster and better with or without using a CDSS. Methods: In a randomized controlled study with a cross-over design, 71 pharmacists performed a total of four MRs, two with and two without the use of a CDSS. The primary endpoint was defined as the time required for the MRs. The secondary endpoints were the number of predefined relevant drug-related problems (DRPs) detected and pharmacist satisfaction. Results: Without the use of a CDSS, pharmacists needed between 25.7% and 30.7% more time to perform a MR than with a CDSS. In addition, significantly more relevant DRPs were detected in the MRs with CDSS than without CDSS (70% vs. 50%; p = 0.0037). Furthermore, participants stated that they felt more confident using a CDSS for MRs than without. Conclusions: Our results demonstrate that MRs can be performed both faster and better when using a CDSS than without. Consequently, community pharmacists benefit from the use of CDSSs for MRs, as do patients in terms of their drug therapy safety.
Association of Myocardial Perfusion and Coronary Flow Reserve with Prognosis in Patients with Aortic Stenosis: Systematic Review and Meta-Analysis
Authors: Aslam Saadia , Haris Muhammad , Nockels Keith , Puranik Amitha , Aleksandric Srdjan , Banovic Marko , McCann Gerry P. , Singh Anvesha
Published: December 2024

Background: Coronary microvascular disease is associated with adverse prognosis in a range of cardiovascular diseases, but its prognostic role in patients with aortic stenosis (AS) is unclear. The aim of this systematic review and meta-analysis is to determine the prognostic role of myocardial perfusion and coronary flow reserve, assessed using non-invasive imaging modalities, in patients with AS. Methods: We conducted a systematic review and meta-analysis of all studies assessing myocardial perfusion reserve (MPR) or coronary flow reserve (CFR) in patients with AS and reporting clinical outcomes, from inception to January 2024. The definition of abnormal MPR/CFR and major adverse cardiovascular events (MACE) was that used in each study. Estimates of effect were calculated from hazard ratios (HRs) and 95% confidence intervals (CIs) using a random-effects model. Results: Four studies comprising 384 participants met the inclusion criteria. Myocardial/coronary blood flow was assessed using Doppler echocardiography (n = 2), PET (n = 1), or cardiac magnetic resonance (n = 1). The median optimal cutoff for MPR/CFR across all studies was 2.01 (range 1.85–2.13), with 109 events. Impaired MPR/CFR was associated with a higher incidence of MACE (HR 3.67, 95% CI: 1.66, 8.09, I2 = 63%) in the overall population. Conclusions: Reduced MPR/CFR is associated with increased risk of MACE in patients with AS, although significant heterogeneity exists in published studies. Further studies are required to establish its role in the risk stratification of asymptomatic patients with AS.
A Comparative Transcriptome Analysis Revealing the Mechanism Underlying the Effect of Maternal Plant Age on Adventitious Rooting of Euryodendron excelsum Cuttings
Authors: Li Ji , Liu Xinyi , Wu Kunlin , Wu Shasha , Zhai Junwen , Fang Lin , Zeng Songjun
Published: December 2024

Euryodendron excelsum H. T. Chang, a monotypic plant endemic to China, exhibits significant variations in adventitious root formation in cuttings across different age groups through unclear molecular mechanisms. In this study, we performed RNA-sequencing (RNA-seq) and data analysis at three stages—initial excision (S0), root primordia (S1), and emergence of adventitious roots (S2)—for lateral buds from transplanted triennial tissue culture seedlings and decennial E. excelsum plants. We identified 13,424 differentially expressed genes (DEGs) between different rooting stages and age groups, including 8216 upregulated and 5208 downregulated genes. A Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that the S1 and S2 DEGs identified were mainly involved in phenylpropanoid biosynthesis, plant hormone signal transduction, plant–pathogen interactions, biosynthesizing various secondary plant metabolites, and starch and sucrose metabolism. Key auxin-pathway genes were expressed at significantly higher levels in culture seedlings than in adult plants, as were WUSCHEL-related homeobox and LATERAL ORGAN BOUNDARIES DOMAIN genes (related to adventitial root growth and development), which together promote the formation, growth, and development of adventitial root primordia. The dysregulated expression of 15 DEGs identified by RNA-seq were verified via real-time quantitative polymerase chain reaction analysis. This study investigates the morphological processes of adventitious root formation in cuttings of E. excelsum of different ages, and the potential molecular mechanisms involved. Our finding provides a basis for research on cutting propagation, conservation applications, and optimization of tissue culture for E. excelsum, and may help improve the rooting rate of E. excelsum cuttings.
Early Stages of Bacterial Colonization Development After Xanthomonas campestris Seed Inoculation in Selected Brassica Species
Authors: Ferby Vojtěch , Ragasová Lucia , Pečenka Jakub , Sękara Agnieszka , Pokluda Robert
Published: December 2024

This study investigates Xanthomonas campestris pv. campestris (Xcc) incidence rates in cabbage, kale, and kohlrabi, focusing on the roots and stems over a 15-day period after sowing. Seeds were inoculated with Xcc, and infection levels were monitored using confocal microscopy combined with fluorescence in situ hybridization. Significant differences in incidence rates were observed across the 15 days using a scale from 0 to 5 (0–100% incidence). Kale exhibited the highest mean incidence rates in roots (3.64), while cabbage and kohlrabi showed greater variability (3.4–3.44). Stem infections were more severe, with kale showing the highest mean levels (4.16), followed by kohlrabi (4.0), and cabbage (3.68). In cabbage roots, incidence rates increased until day 11, after which a significant decline was noted, whereas stem Xcc incidence rates remained stable. Kale roots peaked on day 9, with significant fluctuations on days 13 and 15. Kohlrabi displayed moderate, stable root incidence rates over the 15-day period. In stems, kohlrabi showed a significant increase on day 11, followed by a drop on day 15. Regression analysis revealed a significant positive linear correlation between incidence rate and days of observation in kohlrabi roots. However, no significant trends were observed in stem infections across all species, where incidence rates were high and stable from day 7 onwards. Newly acquired data indicate that the incidence rate of Xcc development depends on the type of vegetable. However, the bacterial occurrence in the root parts does not always correspond with the intensity of Xcc colonization in the stem section of the plants. Even at lower levels of Xcc occurrence in the roots, damage to the vascular bundles can be fatal. These findings offer valuable insights into Xcc infection dynamics, contributing to improved disease management strategies for Brassica crops.
Evaluation of Soil Quality in Different Bletilla striata Agroforestry Systems in Eastern China
Authors: Cao Xiaoqing , Zhang Zhili , Wang Jingjing , Dai Huiyan , Zhang Aiting , Xu Xiaoniu
Published: December 2024

Agroforestry is being promoted as a feasible land use management to improve understory economic benefits. However, there are few studies on species selection and the comprehensive evaluation of soil quality change in rhizoma bletillae (Bletilla striata) agroforestry systems. The soil quality index (SQI) and minimum dataset (MDS) methods can reflect the overall condition and were effective tools for understanding different cultivation systems. In this study, we evaluated the soil quality of four cultivation models (including three agroforestry systems: PeB, moso bamboo (Phyllostachys edulis)–rhizoma bletillae; PoB, plane trees (Platanus orientali)–rhizoma bletillae; CcB, pecan trees (Carya cathayensis)–rhizoma bletillae; and CK, rhizoma bletillae monoculture. The total dataset (TDS) consisted of 15 soil parameters containing physical, chemical, and biological characteristics. The results showed that soil organic carbon (SOC), total nitrogen (TN), and total phosphorus (TP) were finally selected and established as the MDS. Agroforestry could significantly influence soil quality. Compared with CK, the SQI in CcB significantly increased and decreased in PeB and PoB. Soil water content (SWC), nitrate nitrogen (NO3−-N), dissolved organic carbon (DOC), SOC, TN, and TP contents were higher in CcB than in the other cultivation models. Based on various soil indicators and SQI analysis, the CcB was the best in improving soil quality. These findings showed that the soil quality index based on the MDS can be used as an effective indicator for agroforestry systems selection. It provides theoretical guidance for the practice of bionic cultivation and the sustainable management of rhizoma bletillae.
Simulation and Quantitative Assessment of Sensor Placement in a Hydrogen Bus for Risk Mitigation
Authors: Deng Xintao , Sun Jinwei , Yang Fuyuan , Ouyang Minggao
Published: December 2024

The cleanliness of hydrogen energy throughout its life cycle has enabled its applications in transportation and buildings. However, such scenarios often involve the storage and use of hydrogen in enclosed spaces. Ensuring the facility’s safety during hydrogen accidental leakage through rapid detection and emergency measures has been a long-standing topic. In this work, we analyze hydrogen leakage in a hydrogen bus through CFD simulation. By extracting the hydrogen diffusion time and combining it with the leakage frequency and ignition probability, we quantitatively evaluate the placement of the sensors and propose an index for detection system assessment named the average detection delay index (ADDI). A near-field detection sensor was introduced to the system, which reduced the lower ADDI limit of the detection system by up to 10 times while reducing the system cost without changing the level of performance.
High Efficiency in Clean Hydrogen Production Using Water and AlLi Phases Prepared by Mechanical Alloying
Authors: Iturbe-García José Luis , Alvarez-Acosta Diana Laura
Published: December 2024

In this work, the results of clean hydrogen production from the direct chemical reaction between aluminum–lithium compounds and distilled water under normal conditions, without additives or catalysts, are presented. The material was prepared by mechanical alloying using a high-energy Spex-type mill in an Al20Li ratio. Relatively short milling times were programmed for the preparation of AlLi phases. Through this process, two phases (AlLi and Al8.9Li1.1) were identified, which react efficiently to produce clean hydrogen. The experiments demonstrate fast and self-sustained reactions between AlLi phases and distilled water. In both the phase preparation and hydrogen generation, 100% efficiency was achieved. The hydrolysis reaction occurred quickly, and the hydrogen volume generated was 1700 mL/g of material. Under these conditions, aluminum generates 1390 mL of hydrogen, and lithium generates 310 mL/g from both AlLi phases. A single by-product (LiAl2(OH)7·2H2O) was identified. According to the results and the conditions applied in this research, the hydrogen produced does not require prior purification and can therefore be used directly in fuel cells. The AlLi–water reaction is a promising process for generating hydrogen in a simple and relatively short time compared to other hydrogen production methods. In this process, no greenhouse gas emissions were produced.