bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengenalan Ekspresi Wajah untuk Identifikasi Psikologis Pengguna dengan Neural Network dan Transformasi Ten Crops
Authors: Bahri Saeful , Samsinar Riza , Denta Panggalih Sako
Published: August 2023

Pada penelitian ini, dirancang sebuah sistem pengenalan ekspresi wajah untuk identifikasi psikologis pengguna dari data mentah tersimpan dengan model neural network yang dirancang berdasarkan AlexNet dan VGG19 dengan 1 dropout layer tanpa ReLU layer pada classifier layer untuk mengurangi jumlah kebutuhan memori yang dipakai pada GPU dan waktu proses secara signifikan sehingga dapat digunakan pada perangkat berdaya komputasi terbatas. Dataset yang digunakan adalah CK+ dataset dan FER2013 dataset dengan transformasi ten crops. Didapatkan waktu proses yang lebih singkat secara signifikan dibandingkan AlexNet dan VGG19 dan tingkat akurasi sebesar 96.970% menggunakan CK+ dataset dan akurasi sebesar 69.128% dan 70.242% menggunakan public test dan private test FER2013 dataset secara berurutan.In this research, a facial expression recognition system was designed for psychological identification of users from stored raw data with a neural network model designed based on AlexNet and VGG19 with 1 dropout layer and without a ReLU layer on the classifier layer to significantly reduce the amount of memory used on the GPU and processing time so it can be used on devices with limited computational power. The datasets used are CK+ dataset and FER2013 dataset with ten crops transformation. Obtained significantly shorter processing time than AlexNet and VGG19 and an accuracy rate of 96,970% using the CK + dataset and an accuracy of 69,128% and 70,242% using the public test and private test of FER2013 dataset, respectively.
Uji Performa Generator AC 3 phase untuk Pembangkit Listrik Tenaga Piko Hidro Skala Laboratorium
Authors: Saputra Zanu , Hasdiansah Hasdiansah , Vanessa Medeline Citra , Hairullah Hairullah , Andhika Dherry Riski
Published: August 2023

Kebutuhan akan energi listrik saat ini semakin meningkat sehingga energi ini menjadi sumber energi utama yang paling penting. Salah satu upaya untuk memenuhi kebutuhan tersebut dikembangkan Pembangkit Listrik Tenaga Piko Hidro (PLTPH) dengan turbin archimedes screw bilah lima. Dalam pengembangannya dilakukan uji performa generator magnet permanen AC 3 phase dengan kapasitas daya sebesar 500 Watt. Tujuan dari pengujian ini adalah untuk mendapatkan karakteristik output generator sehingga bisa diimplementasikan secara riil. Metode pengujian dilakukan dengan cara menghubungkan poros generator dan poros motor DC shunt dengan kecepatan putaran motor DC dapat dikontrol. Sensor INA219 dan LM393 digunakan untuk mendeteksi nilai arus, tegangan, rpm yang dihasilkan generator selanjutnya diolah menggunakan mikrokontroler. Data real time dapat dimonitoring pada komputer, LCD dan smart phone menggunakan aplikasi blynk. Hasil pengujian menunjukkan bahwa nilai tegangan yang dapat dihasilkan generator dengan penggerak Motor DC pada kondisi optimum yaitu sebesar 45 V AC pada 620 rpm dan pada kondisi minimum menghasilkan 8 V AC pada 91 rpm.
Anaerobic Fluidized Bed Reactor for the Treatment of Tannery Wastewater Using Crushed Tire Scraps as Support Material
Authors: Teran Francisco Javier Cuba , Dauer Paaron Guenka , Cajuela Kássia Barbosa , De Souza Luan Gabriel Xavier
Published: August 2023

Purpose: Due to tannery high pollution potential, is has become necessary to investigate in new treatment technologies that use recycled solid wastes as tires that are abundantly present in the environment.  The application of anaerobic biological processes offers several advantages compared to aerobic processes, including lower energy consumption, reduced sludge production, and a smaller footprint, in addition to the potential utilization of methane as a fuel.
 
Methods: A pilot scale anaerobic fluidized bed reactor was implemented, using crushed tire scraps with diameters ranging from 2.00 mm to 2.83 mm as support material.
 
Results and conclusion: The maximum COD removal efficiency achieved in the system was 77.79% in the first stage and 92.9% in the second stage, while methane production reached 2,930.5 mL. The tire scraps demonstrated efficiency as a support material for biofilm development, with microbial biofilm growth observed through optical microscopy, showing morphologies similar to cocci.
 
Research implications: The implications of this study are to verify the possibility of treatment of tannery wastewater along with the possibility of reuse of an environmental pollutant as tire residues.
 
Originality/value: After the literature research, no study has focused in anaerobic fluidized bed reactors using tire scraps as a support media for the treatment of tannery wastewater.
The Effect of IFRS Adoption, Firm Performance, Audit Quality, Leverage, and Firm Size on Foreign Ownership
Authors: Putri Maria Mathilda , Ekadjaja Agustin
Published: August 2023

IFRS and IAS are internationally accepted accounting standards issued by the IASC/IASB with the aim of uniform accounting standards throughout the world. In diversifying their investments, in addition to understanding the financial statements, investors also need to understand the firm performance and audit quality to increase confidence that the investment will generate profits in the future. The purpose of this research is to determine whether the IFRS adoption, firm performance, and audit quality will significantly affect foreign ownership. The method applied to process research data is a quantitative-descriptive method with unbalanced panel data of eighteen companies registered in the manufacturing sector from 2017-2020. From the results of multiple regression analysis using SPSS, it is known that IFRS adoption has a positive and insignificant effect on foreign ownership. Meanwhile, based on the research results, it is known that the firm performance and audit quality show significant positive results on foreign ownership.
THE IMPACT OF ENTREPRENEURIAL ORIENTATION ON BUSINESS PERFORMANCE THROUGH ENTREPRENEURIAL COMPETENCY AS MEDIATION VARIABLE: A STUDY ON SMES IN CULINARY SECTOR IN JAKARTA
Authors: Raymond Yosafat , Selamat Frangky
Published: August 2023

Enterprises with good business performance are enterprises that are able to survive in fast-moving market. In order to achieve maximum business performance, Small and Medium Enterprises (SMEs) need to have Entrepreneurial Orientation. This study aims to determine the effect of Entrepreneurial Orientation on business performance through Entrepreneurial Competency as a mediation variable among SMEs in culinary sector in Jakarta. The sample used in this study was 100 respondents who are owners of SME businesses in culinary sector in Jakarta. The sample selection technique used was purposive sampling and Smart Partial Least Square (PLS) software version 3.00 was used to make data analysis for this study. The results of this study indicate that innovation, risk taking and proactiveness (Entrepreneurial Orientation) have positive impact on business performance among SMEs in culinary sector in Jakarta.
THE EFFECT OF SOCIAL MEDIA FOR CUSTOMER RELATIONSHIP MANAGEMENT ON SME’S PERFORMANCE WITH SOCIAL COMPETENCE AND SALES INTENSITY AS MODERATING VARIABLES
Authors: Satyagraha Bernardus Aldy , Soelaiman Lydiawati
Published: August 2023

Advances in information technology help companies better understand their customers. Social media is one of many ways MSMEs improve their business performance by approaching consumers through Customer Relationship Management (CRM). Truly, an entrepreneur needs social competence to be able to interact well and possess sales intensity to increase the frequency of interaction. Based on this, this research aims to examine the impact of using social media for CRM on MSMEs’ performance with social competence and sales intensity as moderating variables. The sampling technique used for this research is non-probability sampling and the data were collected through questionnaire in the form of a google form distributed to 97 MSME in Jakarta. The results from structural equation modeling (SEM) method and processed using the SmartPLS version 3.3.3 application showed that social media for CRM, social competence and sales intensity positively influence MSMEs’ business performance in Jakarta. This research also showed that social competence doesn’t moderate the influence of using social media for CRM on MSMEs’ business performance in Jakarta, and the sales intensity weakens the effect of using social media for CRM on business performance of MSMEs in Jakarta.
PROBING DETERMINANTS OF UNIVERSITY ACADEMICIANS’ KNOWLEDGE SHARING INTENTION
Authors: Chin Tay Lee , Yean Tan Fee , Leow Hon-Wei
Published: August 2023

The determinants of information sharing intention are identified in this paper (i.e., managerial support, interpersonal trust, and reciprocity). Data were collected from questionnaires from academicians in the Malaysian private universities. Multiple regression analysis was performed to test the analysis. Management support, interpersonal trust and reciprocity positively influence knowledge sharing intention. The results revealed management support, interpersonal trust and reciprocity play significant roles in determining academicians’ knowledge sharing intentions. Based on the insights of social exchange theory, this study discovered that strong effects of managerial support, interpersonal trust, and reciprocity on information sharing intention. Hence, social exchange theory is extended to the knowledge sharing intention among academicians’ universities. For the university to encourage knowledge sharing intention, they may improve their current management style and maintain a work environment that encourages employees to trust each other.
UNDERSTANDING THE DYNAMICS OF ENTREPRENEURIAL PASSION IN ENTREPRENEURSHIP STUDENTS
Authors: Atlansyah Enrita , Nuringsih Kartika
Published: August 2023

The goal of this study is to analyze the shaping of entrepreneurial passion among students in the practice of entrepreneurial learning at the one university in Jakarta, Indonesia. Exploring this passion is based on two exogenous variables namely emotional support and perceived competence. Students of the Management Program at the Faculty of Economics and Business of Universitas Tarumanagara were involved as source persons in this research. The purposive sampling method is considered for the selection of samples. Some testing stages were used to analyze data including validity, reliability, and structural regression by using the software of Smart-Pls. The result shows both exogenous variables giving significantly affect entrepreneurial passion. Further effects establish good reliability on these constructs and most indicators are valid. Otherwise, found some indicators got a less score on the loading factor so three items are not accurate to measure entrepreneurial passion and one item is less useful to indicate perceived competence. Based on these results, the entrepreneurial education ecosystem needs to improve these items, so students will be more understand the dynamics of entrepreneurial passion specifically for inventing, founding, and developing their venture. It is useful as a mechanism for encouraging the desire of students for entrepreneurial activity.
FACTORS AFFECTING THE STOCK PRICES OF MANUFACTURING COMPANIES LISTED ON THE IDX BEFORE AND DURING THE COVID-19 PANDEMIC
Authors: Audrey Audrey , Yanti Yanti
Published: August 2023

The purpose of this study is to examine the factors that affect stock prices as well as to examine the differences in stock prices before and during the COVID-19 period. The research methods used are multiple linear regression analysis and different tests through the IBM SPSS 26 program. The sampling technique used is purposive sampling which resulted in 82 manufacturing companies listed on the IDX. The results of the regression test before COVID-19 period shows that EPS, PER, and WCTO have an effect on stock prices, while DER and IVTO have no effect on stock prices. The results of the regression test during the COVID-19 period showed that EPS has an effect on stock prices, while PER, DER, WCTO, and IVTO had no effect on stock prices. The result of the different test shows that there is no difference in the average stock prices before and during the COVID-19 period.
FACTORS AFFECTING FINANCIAL DISTRESS IN MANUFACTURING COMPANIES LISTED ON IDX
Authors: Rahayuningtyas Putri , Yanti Yanti
Published: August 2023

This study empirically examines the factors influencing financial distress from 2018-2020. The independent variables used in this study are profitability, liquidity, sales growth, firm size, and firm activities. This study uses quantitative research methods with secondary data obtained from the annual financial statements of manufacturing companies listed on the BEI. There are 102 data from 64 companies selected as research samples based on the purposive sampling method. The data processing in this study was tested using the EViews 12. The results of the regression test showed that company size had a negative and significant effect on financial distress, while profitability and liquidity had a significant positive effect on financial distress and sales growth and activity had no effect on financial distress.
MALWARE DETECTION BASED ON OPCODE FREQUENCY
Authors:   Institute of Information Technology, Baku, Azerbaijan, Baghirov Elshan
Published: August 2023

The amount of new malware has been continuously growing, and its threats are increasing rapidly. Developing new types of detection methods and thereby protecting computer systems from malicious programs has always been of interest to scientific researchers, individuals and organizations. In this work, several classification methods are applied on the dataset which is prepared on the basis of opcodes obtained from known malicious and benign program samples. Dependency between opcodes higher than 70% of total are removed to achieve more relevant results. The other main factors affecting the results of the methods are evaluated. Results prove that Random Forest classifier can classify suspicious programs with higher accuracy than others.
COMPARATIVE ANALYSIS OF K-MEANS AND FUZZY C-MEANS ALGORITHMS ON DEMOGRAPHIC DATA USING THE PCA METHOD
Authors:   Institute of Information Technology, Baku, Azerbaijan, Ahmadov Eltun
Published: August 2023

The concept of demography, which includes the processes such as birth, death, natural increase, improvement of employment and standard of living of the population, migration, etc., occupies a unique place in the global processes of the modern era. In this regard, this article uses clustering algorithms, which are estimated as a demographic data mining technology. For the analysis of demographic data, experiments are performed using k-means and fuzzy c-means clustering algorithms in the Python programming language. The experiment uses PCA method to reduce the dimension and get more effective results. Silhouette, Calinski-Harabasz and Davies-Bouldin indices, and CPU time are used to evaluate the quality of the algorithm. The result of the experiment shows the possibility of achieving an effective result through the k-means and fuzzy c-means clustering algorithms by applying the PCA method in the demographic data analysis.
Forecasting Bulk Cooking Oil Prices for 20 District/Cities in North Sumatra Using Autoregressive Integrated Moving Average (ARIMA) Method
Authors: Simanjuntak Helmonica , Mardianto Is , Sari Syandra
Published: August 2023

Abstract— Frying is a popular method of food preparation in Indonesian society, whether it's for home-cooked meals or snacks bought outside. In Indonesia, there is bulk cooking oil available without a brand, which is cheaper. As a result, the usage of bulk cooking oil is higher compared to branded cooking oil. According to data published by BPS (Central Statistics Agency) in 2021, the per capita consumption of cooking oil in Indonesia reached 0.393L/Capita/week. The consumption of cooking oil in North Sumatra is also relatively high, but the poverty rate in North Sumatra is still high, with a figure of 1,268.19 thousand people.
ARIMA method has advantages where the forecasting follows the data pattern and is flexible with relatively high accuracy. It is a quick and simple process (Hutasuhut, 2014). In ARIMA, there are two ways to determine the model, which are using the Auto Arima function and analyzing the ACF & PACF plots. The data used is the bulk cooking oil price data from January 2021 to January 2023 in Excel format, obtained from the Main Commodity Price System of North Sumatra.
Based on the conducted research, the accuracy of the models generated by the Auto Arima function and the ACF & PACF plots are relatively similar. However, in some cases, the models generated by the Auto Arima function are not significant, although they have higher accuracy than the models generated from the ACF & PACF plots. The highest accuracy level is in Nias Utara district with an accuracy of 99.67% using the ARIMA(3,1,5) model, while the lowest accuracy level is in Nias Barat district with an accuracy of 75.26% using the ARIMA(2,0,0) model.
Index Terms— ARIMA, Bulk Cooking Oil, Auto Arima, ACF&PACF Plot.
Tratamento da depressão ao longo da vida
Authors: Assumpção Junior Francisco Baptista , Allevato Marcelo
Published: August 2023

A depressão é um transtorno mental crônico que caracteriza-se pela presença de tristeza, pessimismo, baixa autoestima, que aparecem com frequência e podem combinar-se entre si. Indivíduos de qualquer idade podem desenvolver a doença. O tratamento mais indicado para cada caso é feito pelo psiquiatra. Em alguns casos é necessário o uso de medicação, em outros apenas a psicoterapia e até mesmo a indicação dos dois tratamentos concomitantemente.
Pengaruh Budaya Organisasi, Kepemimpinan, dan Kepuasan Kerja Terhadap Kinerja Karyawan Dinas Kebudayaan dan Pariwisata Kota Bandung
Authors: Melina Danisa Rizki , Syarifuddin
Published: August 2023

Tujuan penelitian ini adalah untuk menganalisis dan mengetahui pengaruh secara parsial maupun simultan  budaya organisasi, kepemimpinan, dan kepuasan kerja terhadap kinerja karyawan pada Dinas Kebudayaan dan Pariwisata Kota Bandung. Kinerja karyawan yang tercermin dari kinerja organisasi selama tiga periode dari tahun 2019 sampai dengan 2021 masih belum mencapai target yang diharapkan. Penelitian ini adalah deskriptif kausal dan metode penelitian kuantitatif dengan menggunakan metode sampling jenuh dan non-probability sampling dengan jumlah 55 responden. Data tersebut diproses menggunakan program SPSS dan hasil penelitian  menunjukkan bahwa budaya organisasi, kepemimpinan, kepuasan kerja memperoleh nilai F hitung 23,184 > F tabel (2,78) terhadap variabel kinerja karyawan. Serta budaya organisasi secara parsial memperoleh nilai t hitung 2,075 > t tabel (2.00), variabel kepemimpinan memperoleh nilai t hitung sebesar 4,641 > t tabel (2,00), dan variabel kepuasan kerja memperoleh nilai t hitung 3,315 > t tabel (2,00). Dari hasil penelitian kinerja karyawan pada Dinas Kebudayaan dan Pariwisata Kota Bandung dipengaruhi secara parsial oleh budaya organisasi, kepemimpinan, dan kepuasan kerja dan secara simultan menunjukkan bahwa kinerja karyawan Kota Bandung dipengaruhi secara signifikan oleh budaya organisasi, kepemimpinan, dan kepuasan kerja sebesar 57,7% dan sisanya dipengaruhi oleh variable lain.

Kata kunci: Budaya Organisasi, Kepemimpinan, Kepuasan Kerja, dan Kinerja Karyawan.
Methodology for Preliminary Flight Control Actuator Design
Authors: Stephan Ralph , Stumpf Eike , Schottmüller Henri , Röben Tobias , Dreyer Nikolaus , Immler Thomas
Published: August 2023

In this paper, a methodology for the preliminary design of decentralized civil-use flight control actuators is presented that is able to perform the calculations with a very small amount of input data. This enables the user to achieve good actuator key characteristics regarding the weight, power, and volume in the preliminary aircraft design stage without the need for an empirical database. Optionally adjustable setting parameters of the individual components allow the component design to be customized in detail. Both electromechanical and electrohydrostatic actuators are considered. The methodology presented here aims at sizing each individual component of the actuators in terms of volume, mass, and power consumption. The components are broken down into simple geometric shapes where possible. The methodology is evaluated on several actuators of different performance and weight classes from 3.2 kg up to 66.9 kg and provides more accurate results than other common approaches, which is suitable in the preliminary aircraft design stage.
Religion and Spirituality among Child and Youth Care Workers in KwaZulu-Natal
Authors: Bhagwan Raisuyah
Published: August 2023

There has been little empirical research on the salience of spirituality in a child and youth care context. In order to bridge this scholarly gap, this study sought to investigate the views of child and youth care practitioners in KwaZulu-Natal, with regard to the role of religion and spirituality in child and youth care. A cross-sectional survey design was used to gather data from 215 practitioners working in various child and youth care settings. The study found high levels of personal religiosity and spirituality among the sample and significant support for the role of religion and spirituality and the use of spiritually based interventions, despite little educational preparedness in this regard.
“What Is a Good Journalistic Photography”. Book Review: Belenky A. I. Photojournalism in modern media. Moscow, KNORUS, 2022, 164 p.
Authors: Voskresenskaya M. A.
Published: August 2023

The author reviews A. I. Belenky's textbook “Photojournalism in Modern Media”, intended for students at universities. Unlike the bulk of teaching literature devoted to photography, this book focuses not on the technical techniques of photography, but on the basics of journalistic work with photography. Alexander I. Belenky has extensive experience as a photo reporter and bildedactor, teacher, media investigator. Each of the aspects of his professionalism was reflected in the book – in the content of theoretical material, in practical recommendations, in methodological guidelines. There are 12 chapters in the book. Chapters 1–8 describe the functioning of photography in mass media. Chapters 9–11 disclose the conditions that ensure the quality and efficiency of the photojournalist. Chapter 12 provides advice on further professional improvement for a photographer working in mass media. The author's reasoning is accompanied by rich illustrative material, including many works by recognized photo masters. The tests at the end of each chapter encourage self-reflection and creative work. A glossary and a list of recommended literature are also useful for students.
The Birth of the Genre and Rhetorical Strategies of the Writer’s Diary of 1873
Authors: Shatin Yu. V.
Published: August 2023

The article studies the role of Dostoevsky’s editorial activity in the newspaper-magazine “Grazhdanin” (“The Citizen”) in the formation of genre features and rhetorical strategies of the Writer’s Diary of 1873. The author of the article believes that the new form, which arose at the intersection of journalism and fiction, was mainly due to the prospeech attitudes of editorial policy, which simultaneously persuaded the highest strata of the Russian bureaucracy to put an end to the liberal reforms of Alexander II and at the same time tries to expand the circle of readers who adhere to a different social orientation.

Creating a new form of Diary as a literary work, Dostoevsky actively used the resources of rhetoric, while also preserving the achievements in the field of poetic peculiar means such as the paradoxical enthymeme, the reception of implied word? The use of metalanguage and metatext procedures, irony, and parody techniques.

The author of the writer’s Diary actively used non-traditional motives for previous works – false oblivion, masks, obsessions. A number of changes can also be found in such traditional genres of rhetoric as preaching and confession. Having left the post of editor of “The Citizen” at the beginning of 1874, Dostoevsky continued genre and rhetorical experiments, but he was no longer bound by the position of the magazine, which created greater creative freedom in the development of new forms.
The Significance of P. I. Tchaikovsky’s Journalistic Activity in the “Russian Vedomosti”
Authors: Chaikovskaya K. B.
Published: August 2023

The article examines the features of the author's style of Pyotr Ilyich Tchaikovsky as a music critic and the impact  of his journalistic works on the development of music journalism in Russia. It analyzes in detail his texts contained in the newspapers “Russian Vedomosti”, “Moscow Vedomosti”, “Modern Chronicle” and reviews the assessment of his musical and critical activity provided by the outstanding Russian music critics G. A. Laroche and A. N. Serov. The article concludes that despite his obvious literary talent, Tchaikovsky did not consider music journalism his profession. The composer's work in musical journalism became a bright discovery for his contemporaries as well.  The sharpness of his gaze as the music critic caught those details of acting, instrument skills, or composing techniques that an ordinary spectator did not know about, considering all fashionable musical trends from an idealistic perspective, and professional musicians and actors did not want to share, concealing their omissions. Tchaikovsky did not follow the tastes of the high society of Moscow and St. Petersburg and was not afraid to denounce world-famous opera singers, openly pointing out their sometimes lack of talent or undisguised lack of desire to improve their artistry. Complaining about the attacks on his critical activity, Tchaikovsky noted that this work, no matter how difficult it was, not only for him but also for any critic, played a crucial role in leveling up music education, which is the key to the development of music and journalism.
Forming the Theoretical Framework of the “Cancel Culture”: Conceptual Roots and Current Interpretations
Authors: Dunas D. V. , Gureeva A. N. , Kireeva P. A.
Published: August 2023

The paper examines and systematizes the most common theoretical approaches to the “cancel culture”, a widely spread mediatized phenomenon in contemporary social life. It focuses on analyzing primarily English-language academic discourse, since there are significantly more scholars examining this phenomenon. In addition to the literature review, the study uses monitoring methods of media publications on the related topic, which allows for revealing tendencies and dynamics of public and academic interest in the analyzed phenomenon. The paper describes the theoretical origins of the “cancel culture”, offers the most stable definitions and interpretations of the “cancel culture” today, and considers the concept of “cancel culture” in the context of the struggle for social justice. The theoretical interpretation of the phenomenon also includes a critical perspective: the “cancel culture” is condemned for its incompatibility with the promoted democratic ideals to the methods used by activists, the abuse of media power, etc. The “cancel culture” is criticized for the practice of lynching, or so-called “digital vigilantism”. Obviously, the “cancel culture” is both a positive and a negative phenomenon, which should be viewed in a comprehensive and in-depth way.
Russian-Language Media of YouTube: Trends of the “Fifth Power” in 2021
Authors: Kruglova L. A. , Kostrukov A. I.
Published: August 2023

Purpose. Compared to 800 million users in 2012, global YouTube reached over 2 billion monthly active users in 2021. Just over a quarter of the world’s population visits YouTube every month. Worldwide, users watch over 1 billion hours of content every day. Russia is in the top five countries in 2021 in terms of the total estimated number of YouTube users – 58 million. According to Why Video, over 65 % of viewers perceive YouTube content as real life. Daily statistics show the scale of YouTube and it becomes clear that this is not just social media and video hosting, but a full-fledged “fifth power”. 

Results. Based on the analysis of 127 Russian-language media YouTube channels conducted in the fall-winter of 2021, as well as on expert interviews and monitoring of sociological research, the authors are trying to determine the vectors of development of the enormously popular platform.

Conclusion. YouTube and audiovisual networks are becoming not only a means of procrastinating and entertaining viewers, but also an informational and educational source. Social media, and in particular YouTube, have established their own full-fledged media space with their own laws, trends, culture, fashion, etc. Most YouTubers create a completely competitive product without large-scale professional, especially television, production facilities, while their audience is many times greater than the television one. They re-invent journalistic genres that seem outdated on television and radio, raising hype about them. They earn money with the help of not only the YouTube platform but also advertising integrations. YouTubers grew into powerful media, developing a personal brand, choosing the most comfortable social media platforms for themselves, and successfully mastering new ones.
Decree Law in the Mechanism of Constitutional Modernization
Authors: Drobot S. E.
Published: August 2023

The article analyzes the influence of the decree right on the process of transforming the political institutions of modern Russia, considers the practice of the functioning of the Russian presidency in terms of determining the priority directions for the development of the state, national goals and modernization of the constitutional space of Russia. The study raises the problem of the correlation of this practice with the doctrines of liberal republicanism and the separation of powers. The author made an attempt to show that the phenomenon of decree law has a progressive significance for the constitutional development of Russia and can be aimed at expanding the use of forms of deliberative democracy in domestic constitutionalism. It is concluded that it is necessary to improve the control over the implementation of the program and political acts of the head of state by the presidential administration and the introduction of guarantees for the participation of the legal scientific community in the process of discussing constitutional amendments.
Dental student perceptions on clinic supervision: A qualitative study
Authors: Colina Trinette Chang
Published: August 2023

Objectives:

The integration of knowledge from basic sciences to clinical dentistry is an important learning process experienced by dentistry students. The entire process is facilitated by the faculty, officially recognized as the clinical supervisor. This research described student perceptions regarding clinical supervision in a Philippine dental school.

Materials and Methods:

This study used the qualitative method through focused group discussions (FGDs). For each FGD, the target sample size is six to ten participants. Guide questions were prepared. A facilitator who has a background in Master of Health Professions Education and prior experience in facilitating was requested to conduct the FGD proceedings. Audio recording was used and the minutes were transcribed to facilitate analysis and sent to the facilitator and participants after 1 week for validation.

Results:

Five FGDs consisting of six students each were conducted to probe on students’ perception of clinical supervision. In total, 30 students participated. Most were female junior students. The first theme which arose from the student perceptions was the lack of time due to the high faculty-student ratio. A second theme which arose was that certain faculty traits affect students’ perceptions of clinical supervision. Faculty characteristics which affected them positively were patience, approachability, and fairness. Faculty characteristic which affected them negatively was preferential treatment or favoritism that they see in the clinics.

Conclusion:

Students mentioned faculty traits of patience, approachability, and fairness as positive traits in a clinical supervisor. On the other hand, students agreed that the general lack of time due to the faculty-student ratio made it difficult for the faculty to allot sufficient attention to each student.
Assessment of awareness among parents about preventive measures of oral health problems in children
Authors: Chandak Jayashri Navalkishor , Chahande Jaishree
Published: August 2023

Objectives:

Oral health is an essential factor of day to day life. The habit of maintaining oral health and daily routine for the same should be incorporated into the children from their childhood. An oral cavity free from all disease is maintained by awareness about the preventive measures. Parents play a key role in their kids’ life, thus their understanding toward oral health are important. The aim of the study was to assess awareness among parents about preventive measures of oral health problems in children. The main objective is to assess awareness of problems related to oral cavity and to encourage parents to maintain good oral hygiene of their children by adapting preventive measures and also to know the requirement of encouraging oral health promotion programs.

Materials and Methods:

A pre-validated questionnaire was distributed among the parents of children aged till age of 12 years old. The questionnaire related to oral hygiene practice and awareness of oral health problems including 13 questions were distributed through Google forms to parents through WhatsApp and email.

Results:

A questionnaire with 13 items was used to evaluate parents’ knowledge of oral health. Forty-two men and 62 women made up the 104 parents of children between the ages of 6 months to 12 years. Demographic details include 59.61% of females and 40.38% of males were participated. A total of 104 parents participated in the study. In a poll of 104 parents, it was determined that 81.73% of the parents believed that brushing twice a day was important, and 51.92% of the parents felt that they should visit their dentist at 6–12 months of age of child. It was determined from the survey that 81.73% of the parents wanted more information on how to maintain their children’s teeth better. To address all of the survey’s questions, an educational brochure was issued once the questionnaires were collected. It is essential that parents and dentists teach their kids good brushing and oral hygiene habits.

Conclusion:

Although the parent’s understanding of the many elements that affect dental health was good, there are some aspects where still lack of knowledge exist that must be taken into account. Parents’ education can be the most encouraging factor in preventing oral health problems because prevention is always preferable to cure. To enhance awareness and start dental caries prevention techniques early, it is necessary to supervise dental health education initiatives that are directed at parents of school-aged children.
Collision Induced Unfolding Reveals Disease-Associated Stability Shifts in Mitochondrial tRNAs
Authors: Anders Anna , Tidwell Elizabeth , Gadkari Varun , Koutmos Markos , Ruotolo Brandon
Published: August 2023

Ribonucleic acids (RNAs) remain challenging targets for structural biology, creating barriers to understanding their vast functions in cellular biology and fully realizing their applications in biotechnology. The inherent dynamism of RNAs creates numerous obstacles in capturing their biologically relevant higher-order structures (HOSs), and as a result, many RNA functions remain unknown. In this report, we describe the development of native ion mobility-mass spectrometry (IM-MS) and collision induced unfolding (CIU) for the structural characterization of a variety of RNAs. We evaluate the ability of these techniques to preserve native structural features into the gas-phase across a wide range of functional RNAs. Finally, we apply these tools to study the elusive mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS)-associated A3243G mutation. Our data demonstrate that our experimentally determined conditions preserve some solution-state memory of RNA via the increasing complexity of CIU fingerprints by RNA HOS and the retention of predicted magnesium binding events. Relating to the role of MELAS-inducing mutations in mitochondrial trans-fer RNA (mt-tRNAs), significant differences in collision cross-section (CCS) and stability are observed as a function of the A3243G mutation across a subset of the mitochondrial transfer RNA (tRNA) maturation pathway. We conclude by discussing the potential application of CIU for the development of RNA-based biotherapeutics and, more broadly, transcriptomic characterization.
STOPLIGHT: A Hit Scoring Calculator
Authors: Wellnitz James , Martin Holli-Joi , Hossain Mohammad , Rath Marielle , Fox Colton , Popov Konstantin , Willson Timothy , Muratov Eugene , Tropsha Alexander
Published: August 2023

We introduce STOPLIGHT, a web portal to assist medicinal chemists in prioritizing hits from screening campaigns and selection of compounds for optimization. STOPLIGHT incorporates services to assess 6 physiochemical and structural properties, 6 assay liabilities, and 11 pharmacokinetic properties for any small molecule represented by its SMILES string. We briefly describe each service and illustrate the utility of this portal with a case study. The STOPLIGHT portal provides a user-friendly tool to guide hit selection in early drug discovery campaigns, whereby compounds with unfavorable properties can be quickly recognized and eliminated. Availability and implementation: STOPLIGHT is freely accessible at https://stoplight.mml.unc.edu/.
Noble metal high entropy alloy for mid infrared metasurfaces
Authors: Nishijima Yoshiaki , Sudo Teruaki , Matsuo Yasutaka , Juodkazis Saulius
Published: August 2023

We have experimentally determined the complex permittivity of a high entropy alloy (HEA) composed of five noble metals: Au, Ag, Cu, Pd, Pt. The permittivity was measured in a wide range of wavelengths from ultraviolet via visible to mid-infrared. The experiments and numerical simulation results show a possibility to create perfect absorber and emitter metasurfaces from such noble HEA. The lattice constant and electron work function of the noble HEA were determined to be 0.396 nm and 4.8 pm 0.4 eV, respectively.
Non-threaded isomers of sungsanpin and ulleungdin lasso peptides inhibit H1299 cancer cell migration
Authors: Digal Lori , Samson Shiela , Stevens Mark , Ghorai Abhijit , Kim Hyungyu , Mifflin Marcus , Carney Keith , Williamson David , Um Soohyun , Nagy Gabe , Oh Dong-Chan , Mendoza Michelle , Roberts Andrew
Published: August 2023

Lasso peptides are a structurally distinct class of biologically active natural products, defined by their short sequences with impressively interlocked tertiary structures. Their characteristic peptide [1]rotaxane motif confers marked proteolytic and thermal resiliency, and reports on their diverse biological functions have been credited to their exceptional sequence variability. Because of these unique properties, taken together with improved technologies for their biosynthetic production, lasso peptides are emerging as a designable scaffold for peptide-based therapeutic discovery and development. Although the defined structure of lasso peptides is recognized for its remarkable properties, the role of the motif for imparting bioactivity is less understood. For example, sungsanpin and ulleungdin are natural lasso peptides that similarly exhibit encouraging cell migration inhibitory activities in A549 lung carcinoma epithelial cells despite sharing only one-third sequence homology. We hypothesized that the shape of the lasso motif is beneficial for the preorganization of the conserved residues, which might be partially retained in variants lacking the threaded structure. Herein, we describe solid-phase peptide synthesis strategies to prepare acyclic, head-to-sidechain (branched), and head-to-tail (macrocyclic) cyclic variants based on the sungsanpin (Sun) and ulleungdin (Uln) sequences. Proliferation assays and timelapse cell motility imaging studies were used to evaluate the cell inhibitory properties of natural Sun compared alongside the synthetic Sun and Uln isomers. These studies demonstrate that the lasso motif is not a required feature to slow cancer cell migration, and more generally show that these non-threaded isomers can retain similar activity to the natural lasso peptide despite the differences in their overall structures.
Navigating the Chemical Space and Chemical Multiverse of a Unified Latin American Natural Product Database: LANaPDB
Authors: Gómez-García Alejandro , Acuña Jiménez Daniel A. , Zamora William J. , Barazorda-Ccahuana Haruna L. , Chávez-Fumagalli Miguel Á. , Valli Marilia , Andricopulo Adriano D. , Bolzani Vanderlan da S. , Olmedo Dionisio A. , Solís Pablo N. , Núñez Marvin J. , Rodríguez Pérez Johny R. , Valencia Sánchez Hoover A. , Cortés Hernández Héctor F. , Medina-Franco José L.
Published: August 2023

The number of databases of natural products (NPs) have increased substantially. Latin America is extraordinarily rich in biodiversity enabling the identification of novel NPs, which has encouraged both the development of databases and the implementation of those that are being created or are under development. In a collective effort from several Latin American countries, herein we introduce the first version of Latin American Natural Products Database (LANaPDB), a public compound collection that gathers the chemical information of NPs contained in diverse databases from this geographical region. The current version of LANaPD unifies the information from six countries and contains 12,959 chemical structures. The structural classification showed that the most abundant compounds are the terpenoids 63.2%, phenylpropanoids 18% and the alkaloids 11.8%. From the analysis of the distribution of properties of pharmaceutical interest, it was observed that many LaNaPDB compounds satisfy some drug-like rules of thumb for physicochemical properties. The concept of the chemical multiverse was employed to generate multiple chemical spaces from two different fingerprints and two dimensionality reduction techniques. Comparing LaNaPDB with FDA-approved drugs and the major open-access repository of NPs, COCONUT it was concluded that the chemical space covered by LaNaPDB completely overlaps with COCONUT and in some regions with FDA-approved drugs. LANaPD will be updated adding more compounds from each database plus the addition of databases from other Latin American countries. The database is freely available at https://github.com/alexgoga21/LaNaPDB.
Pitfalls and considerations in determining the potency and mutant selectivity of covalent epidermal growth factor receptor inhibitors
Authors: Hoyt Kristopher W , Urul Daniel A , Ogboo Blessing C , Wittlinger Florian , Laufer Stefan A , Schaefer Erik M , May Earl W , Heppner David E
Published: August 2023

Pursuing enzyme inhibitors with molecules that form covalent bonds with the desired target is an attractive focus in drug development that is increasing in prevalence. However, challenges arise when carrying out assessments of their time-dependent inhibitory properties as well as making correlations with values reported in the literature. Given the prominent focus on the Epidermal Growth Factor Receptor (EGFR) tyrosine kinase in oncology, and the diverse structures and binding modes of covalent EGFR inhibitors, this perspective seeks to explore various broadly relevant factors that arise in the measurement of kinetic parameters within this class of drugs. A review of several studies indicates that variable literature potency values require investigators to include appropriate reference molecules and consistent substrate conditions for experimental consistency and proper benchmarks. The impact on covalent inhibitor potency with respect to common buffer conditions and compound liquid handling is surveyed highlighting the importance of multiple experimental variables when conducting these assays. Additionally, when assessing the potency for inhibitor selectivity in targeting EGFR mutants over wild-type (WT), it is ideal to consider ratios of true potency due to the variable ATP substrate binding affinities. The overview presented here, although most directly applicable to the tyrosine kinase inhibitor field, serves inhibitor assessments broadly by providing guided insights into conducting biochemical assays for designing and validating next-generation covalent inhibitors.
Thermal Ca^2+/Mg^2+ Exchange Reactions to Transform Abundant Silicates Into Alkaline Materials for Carbon Dioxide Removal
Authors: Chen Yuxuan , Kanan Matthew
Published: August 2023

The removal of CO2 from the atmosphere (CDR) on the multi-hundred gigaton (Gton) scale is essential for nearly all strategies to achieve net-zero greenhouse gas emissions and limit global warming to 2°C by 2100. CDR must capture CO2 from air and safely sequester it. Mg-rich silicate minerals have the capacity to remove ~10^5 Gton CO2 and sequester it in the form of indefinitely stable and innocuous Mg carbonates, but their carbonation rates in air are far too slow for practical use. Here we show that simple thermochemical Ca^2+/Mg^2+ exchange reactions convert CaO and diverse Mg silicates (olivine, serpentine, augite) into Ca2SiO4 and MgO. While the input mineral shows no carbonation in ambient air over 6 months, Ca2SiO4 completely carbonates to form CaCO3 and SiO2 within weeks. Although MgO carbonates at a slower rate in air, it can be fully carbonated under 1 atm CO2 at ambient temperature within hours. By combining it with CaCO3 calcination to generate CaO, this chemistry enables a closed cycle for CDR wherein the Ca2SiO4 generated by Ca^2+/Mg^2+ exchange is used to capture CO2 from air and MgO is used to recapture the CO2 released by calcination. Analysis of the thermal requirements indicates that this cycle could be performed with an energy demand per ton CO2 removed that is comparable to the energy demand for just capturing CO2 using direct air capture (DAC) technologies. We also demonstrate analogous transformations using CaSO4 as the CaO source. The chemistry described here could unlock the use of Mg-rich silicates as a vast resource for safe, permanent, and verifiable CDR.
A Tale of Change and Continuity: Three Storm Surges, and Three Towns, Under Three Flags
Authors: James F. Warren  , Lisa Woodward
Published: August 2023

The historical record, though incomplete, shows that typhoon generated storm surges cause extreme damage and loss of life in the Philippine archipelago. Storm surges associated with typhoons historically make sea-to-land crossings. There is an annual average of nineteen tropical cyclones occurring in the Philippine’s area of responsibility, of which an average of nine cross the country. There are few areas of the archipelago that have not been affected by storm surges. This paper investigates the crucial role and impacts of this natural hazard in certain areas of the Philippines that have been exposed to typhoons and storm surges across the centuries. The paper discusses the character of the storm surge, highlights some of the worst storm surge catastrophes that have occurred outside the Philippines, and then focuses on three storm surge events in the Visayan Islands of Samar and Leyte. On October 12, 1897, November 24-26, 1912, and November 3-11, 2013, the exposed coastal towns of Hernani and Guiuan on Samar and Tacloban on Leyte were destroyed by storm surges. The recurrent damage and loss of life caused by storm surges and cyclonic storms has increased in these three places as the complex cascade chain of the hazard changed through time, shifting from thousands to millions of people displaced and their livelihoods and communities destroyed on three occasions between October 1897 and November 2013.
Ruth Morgan on "Health, Hearth, and Empire: Climate, Race, and Reproduction in British India and Western Australia
Authors: Ruth Morgan
Published: August 2023

In this interview, Ruth Morgan discusses her article, “Health, Hearth and Empire: Climate, Race and Reproduction in British India and Western Australia,” which was first published by Environment and History in 2021.