bluuebunny/crossref_metadata_2025 huggingface dataset:
Acanthamoeba Keratitis Leading to Loss of Sight: A Case Study
Authors: Abdelmajeed M. Imam Mohamed , Mahgoub E. S.
Published: April 2024

Acanthamoeba is a pathogenic free-living amoeba which is ubiquitously dispersed in the environment such as soil, water, and air. It is a recognized cause of keratitis in man, and can lead to loss of sight of the affected eye in 15% of cases, if undiagnosed and untreated. The typical risk factors for Acanthamoeba keratitis (AK) are minor eye trauma, contact lens wearing, agriculture work, and swimming in unchlorinated pools. The early clinical features of AK usually include unilateral ocular pain and/or redness, impaired sight, and photophobia. In this communication we describe a case of AK which resulted in loss of sight in an adult male farmer.

Key words: Acanthamoeba, keratitis, sight loss
Prevalence of De Quervain’s Tenosynovitis in Male Hairdressers of Southern Pune
Authors: Brahmane Pankaj , Jadhav Tejaswini , Jerome Albin
Published: April 2024

Aim: To study the prevalence of De Quervain’s Tenosynovitis in Male Hairdressers of Southern Pune.
Objectives: To diagnose the De Quervain’s Tenosynovitis in Male Hairdressers by using Finkelstein Test.
Methodology: 296 subjects were selected according to the inclusion and exclusion criteria. A written informed consent was taken from the subjects in the language best understood by them. The study subjects were explained about the procedure. The test is performed on both the hands. A positive test is indicated by pain over the abductor pollicis longus and extensor pollicis brevis tendons at the wrist and is indicative of a de Quervain’s Tenosynovitis. The data was collected and was statistically analyzed.
Statistics & Results: 51.35% of the total population assessed had De Quervain’s Tenosynovitis on Dominant side and 1% had De Quervain’s Tenosynovitis on Non-Dominant side. It was also found that 14% of Hairdressers were having pain on Activity, 12.99% of Hairdressers were having pain on Rest and 72% of Hairdressers were having No pain on Activity and Rest.
Conclusions: The study concluded that there 51.35% prevalence of De Quervain’s Tenosynovitis in Hairdressers because of their working pattern.
Clinical Implications: This study can be used to make people aware and prevent the occurrence or worsening of existing De Quervain’s tenosynovitis. People can be given ergonomic advice like taking frequent breaks while working and resting the hand.

Key words: De Quervain’s Tenosynovitis, Hairdressers, Finkelstein Test, Cumulative Trauma Disorders.
Praktik Pemeliharaan Tanaman Kelapa Sawit Di PT. Mitra Austral Sejahtera Kalimantan Barat
Authors: Oktavia Angeline , Widowati Widowati
Published: April 2024

Artikel ini membahas pemeliharaan tanaman kelapa sawit di PT. Mitra Austral Sejahtera, Kalimantan Barat. sebagai komoditas utama yang mempengaruhi peningkatan perkebunan kelapa sawit di Indonesia. Pengendalian gulma yang efektif dan pemupukan yang tepat berperan penting dalam meningkatkan produktivitas perkebunan kelapa sawit. Oleh karena itu diperlukan informasi teknis yang bertujuan untuk memberi informasi tentang pemeliharaan tanaman kelapa sawit, khususnya yang berkaitan dengan pengendalian gulma dan pemupukan. Kegiatan ini dilaksanakan mulai Agustus sampai Oktober 2023 di PT. Mitra Austral Sejahtera 1, Dusun Melobo, RT. 004 Nadok, Desa Rahayu, Kecamatan Parindu, Kabupaten Sanggau, Provinsi Kalimantan Barat. Metode pengumpulan data dan informasi dilakukan dengan pengamatan dan wawancara langsung di lapangan (data primer) dan studi pustaka (data sekunder). Perkebunan kelapa sawit di PT. Mitra Austral Sejahtera 1 sebagian besar merupakan tanaman menghasilkan yang sudah memasuki usia tua yaitu sekitar 24-26 tahun. Pengendalian gulma dilakukan secara manual dan menggunakan bahan kimia, dengan jenis gulma berbahaya seperti alang-alang dan sembung rambat yang dapat menurunkan produksi hingga 20%. Pemupukan dilakukan dengan memperhatikan curah hujan yang optimal antara 100-250 mm per bulan. Pemupukan di PT. Mitra Austral Sejahtera 1 dilakukan sekali dalam setahun dengan jenis pupuk NPK 13 dengan dosis 3kg/pokok.
Optimalisasi Peran Aktif Mahasiswa Dalam Membangun Pemberdayaan Kegiatan Di Lingkungan Masyarakat
Authors: Mellinda Nabillah Novi , Salsabilla Tasya Annisa , Sysfahrina Sysfahrina , Putri Amelia , Fahrenzia Dika Satura , Azhar Hadi Akmal , Munajat Ahmad , Prasetyo Bagus Aris , Fortuna Refni , Nasrulloh Muhamad Aziz , Mefa Aldib Rhamadani
Published: April 2024

Kuliah Kerja Nyata (KKN) Institusi Teknologi dan Bisnis Ahmad Dahlan Jakarta 2023 telah dilaksanakan dengan bantuan kader Jumantik di RW 01, Kelurahan Penjaringan Jakarta Utara, Kecamatan Penjaringan, Jakarta Utara. KKN ini merupakan bentuk pengabdian mahasiswa ITB-AD kepada masyarakat dengan memberikan bantuan ilmu dan tenaga melalui mitra. Tujuan KKN tahun ini adalah meningkatkan kesadaran terhadap bahaya bullying dan pelecehan seksual pada SD/MI dan MTS Al-Falah, serta memberikan penyuluhan tentang tata cara menggunakan bahan alami untuk mengusir nyamuk agar terhindar atau mencegah penyakit demam berdarah. Selain itu kegiatan jumantik ini terdiri dari melakukan pemeriksaan jentik-jentik pada rumah warga dan melakukan survei data jumantik. Metode yang digunakan dalam penelitian itu observasi, interview dan dokumentasi. Berdasarkan hasil tersebut maka bahan alami yang telah kami berikan dalam penyuluhan kepada kader jumantik dapat disampaikan kepada masyarakat sekitar untuk dipraktikkan secara langsung. Sekolah juga diharapkan untuk selalu memperhatikan siswa/i agar terhindar dari perilaku bullying dan pelecehan seksual. Sehingga siswa/i dapat menghindari perilaku bullying serta pelecehan seksual.
Pelatihan Komputer Kepada Anak-Anak di Desa Tebachi, Kecamatan Kalideres, Kota Jakarta Barat
Authors: Setiawan Yohanes Ari , Nitsa’e Ayub Ferdinan , Richard Richard , Anggun Anggun , William Jantro Hans , Suhartanto Suhartanto , Sianturi Hana Grace , Puhiri Fredrik
Published: April 2024

Teknologi Informasi dan Komunikasi (TIK) memiliki peran penting dijaman digital sekarang ini. Manusia dituntut untuk bisa beradaptasi terhadap teknologi tersebut khususnya adalah komputer. Keterampilan dasar penggunaan komputer sangat penting untuk dikuasai, agar lebih maksimal dalam memanfaatkan penggunaan komputer. Pada kenyataanya belum semua manusia bisa menggunakan komputer terutama di pedesaan. Anak-anak di Desa Tebachi menjadi salah satu contoh yang belum terampil menggunakan komputer. Melihat masalah ini penulis ingin melakukan pengabdian masyrarakat untuk melakukan pelatihan komputer pada anak-anak di Desa Tebachi. Pelatihan tersebut terlaksana pada Kamis, 6 Juli 2023 pukul 15.00 – 17.30 yang dilakukan di Desa Tebachi. Peserta sebanyak 15 anak-anak dari umur 5 -15 tahun. Pelatihan terdiri dari pengenalan perangkat komputer, praktek menggunakan komputer, games ringan, dan evaluasi pelatihan. Hasil pelatihan bisa dikatakan berhasil karena antusias dan peran aktif dari anak-anak di saat pelatihan. Penulis menggunakan skala 1-5 dengan angka 1 sebagai sangat terendah dan angka 5 sangat tinggi setiap penilaian.  Penilaian untuk acara secara keseluruhan   rata-rata adalah 4.8 yang berarti acara sangat menarik.  Nilai Rata-rata 4,67 berarti penyampaian materi sangat bermanfaat. Nilai Rata-rata  4,8 berarti  interaksi dengan pemateri sangat baik. Pengurus Desa menharapkan pelatihan terus berlanjut dan tidak berhenti dikarenakan terasa sekali dampak manfaat pelatihan tersebut kepada anak-anak di Desa Tebachi.
Expo Kewirausahaan: Pembentukan Jiwa Entrepreneur Sejak Dini Pada Siswa Siswi Di SDN Blubuk 03 Kabupaten Tegal
Authors: Desvita Amanda Fitria , Suliswaningsih Suliswaningsih
Published: April 2024

Peningkatan jumlah penduduk dan tingkat pengangguran yang signifikan di Indonesia menimbulkan permasalahan sosial, termasuk kurangnya lapangan pekerjaan. Untuk mengatasi hal ini, penting untuk meningkatkan potensi kewirausahaan masyarakat, terutama di kalangan generasi muda. Salah satu upaya yang dilakukan adalah melalui program expo kewirausahaan di sekolah dasar. Penelitian ini menggunakan pendekatan kualitatif dengan fokus pada peningkatan potensi entrepreneur pada peserta didik Sekolah Dasar Negeri Blubuk 03, Kecamatan Dukuhwaru, Kabupaten Tegal melalui kegiatan expo kewirausahaan. Data diperoleh melalui observasi lapangan dan pengumpulan dokumen terkait kegiatan expo. Hasil analisis menunjukkan bahwa pendidikan kewirausahaan memiliki dampak positif terhadap kecenderungan siswa untuk menjadi wirausaha, serta peran guru dalam memfasilitasi kegiatannini sangat penting. Melalui kegiatan expo, siswa-siswi dilatih untuk memiliki ide kreatif, inovatif, dan kemandirian dalam mengelola produk serta mempromosikannya. Kuesioner yang diberikan kepada peserta menunjukkan bahwa sebagian besar siswa menyukai kegiatan expo kewirausahaan, dan banyak dari mereka berminat untuk menjadi wirausaha di masa depan. Kesimpulannya, kegiatan expo kewirausahaan efektif dalam mengembangkan potensi kewirausahaan peserta didik sekolah dasar, serta membentuk karakter kemandirian dan inovasi sejak dini. Diharapkan program ini dapat menjadi model pembelajaran efektif dalam mengembangkan kewirausahaan di sekolah dan berkontribusi pada pembangunan ekonomi Indonesia melalui generasi muda yang siap berwirausaha.
Autonomous Devices with an Evaporation-Condensation Cycle for Thermal Control of Heat-Loaded Equipment
Authors: Vasil’ev L. L. , Zhuravlev A. S. , Kuz’mich M. A. , Grakovich L. P. , Rabetsky M. I. , Dragun L. A.
Published: April 2024

The design, principle of operation and results of the study of two-phase heat conductors, specifically loop thermosyphons with a horizontally located evaporator and condenser and a porous coating in the evaporator, intended for the thermal control of heat-loaded equipment are presented. Two modifications of thermosyphons were tested: 1) with a cylindrical evaporator and liquid cooling of the condenser; 2) with a flat evaporator and an air-cooled condenser. The porous wick contributes to the uniform distribution of the liquid as well as of the heat flow in the longitudinal and cross sections of the evaporator, the alignment of the temperature field over the surface of the evaporator and, consequently, of the cooled object. Thermosyphons are made of copper, working fluids were water and freon R245fa. The aim of the work was to determine the main thermal characteristics of the developed devices: heat transfer capacity, temperature fields along the body, thermal resistance of the thermosyphon and its parts at different thermal loads and filling levels with working fluids. Experimental equipment and research methods are described. The studied devices also have characteristics that allow them to be used in thermal control systems for objects with a high heat release intensity: low thermal resistances, stable operation in a wide range of heat flows, high heat transfer capacity (up to 1.5–1.7 kW), short start-up time, dynamic exit to a stationary mode when the heat load changes. The created devices are designed for the thermal control of electronic, electrical and other equipment with intense heat release.
The role of service innovation and competitive advantage ad mediators of product innovation on marketing performance: Evidence from the SME manufacturing firms in Indonesia
Authors: Sutanto J. E. , Harianto Eric , Krisprimandoyo Denpharanto Agung
Published: April 2024

This paper aims to explore the role of service innovation and competitive advantage as a mediator of product innovation on marketing performance of small and medium enterprises (SMEs) manufacturing firms in Indonesia. The sample size used in the research was 180 SMEs and the sampling technique is area (cluster) sampling. Furthermore, the sample criteria or respondents, whose researchers' recommendations for filling in the research instrument are managers and can represent company owners. Findings provide empirical evidence that service innovation on marketing performance; competitive advantage on marketing performance; product innovation on service innovation; and product innovation on competitive advantage have positive and significant effects, except the influence of competitive advantage on marketing performance which was not significant.
The factors influencing on “made in Vietnam” electric cars demand
Authors: Anh Nguyen Thi Van , Tung Hoang Thanh , Hung Lam Tuan , Tuyet Truong Thi
Published: April 2024

This article examines the factors affecting the demand for “Made in Vietnam” electric cars. The research results 6 main factors affecting the demand for “Made in Vietnam” electric cars including (1) Prices of “Made in Vietnam” electric cars; (2) Consumer income; (3) Consumer taste; (4) Price of related goods (including substitutes and complementary goods); (5) Market expectations for “Made in Vietnam” electric cars; (6) Policy institutions and consumers’ psychology towards environmentally friendly products. On that basis, the research team used Eviews8 software to test the impact of price factors and related commodity prices on the quantity and demand of electric cars. The results also indicate that when the price of “Made in Vietnam” electric cars increases by 1%, the quantity demanded for “Made in Vietnam” electric cars decreases by 1.39%; When income increases to 1%, consumers will be willing to save 0.26% to buy an electric car. If the price of substitute goods increases by 1%, the demand for “Made in Vietnam” electric cars will increase by 1.91%, and if the price of complementary goods increases by 1%, the demand for “Made in Vietnam” electric cars will decrease by 3.12%. From the results obtained, the research team has some recommendations to stimulate demand for “Made in Vietnam” electric cars, a product with many advantages in the green fuel era.
The influence of supply chain and knowledge-oriented leadership on the performance of village financial system operators and its implications on the level of village welfare
Authors: Fauzi Fauzi , Effendi Rustam , Basrowi Basrowi , Muslihudin Muhamad
Published: April 2024

The objective of this study is to examine the direct and indirect impact of Supply Chain and Knowledge-Oriented Leadership on the Performance of Village Financial System Operators and its consequences for the Level of Village Welfare. This study employed quantitative methodologies, using Saturation sampling techniques, and obtained a sample of 131 respondents who were village financial information system operators, consisting of 131 villages in Pringsewu Regency, Lampung Province, Indonesia. The data obtained from the surveys was further analyzed using Structural Equation Modeling-Partial Least Squares (SEM-PLS). The findings of the research and data analysis indicate that: Knowledge-Oriented Leadership has a direct and substantial impact on the Performance of Village Financial System Operators. It also has a direct and substantial impact on the Village Welfare Level. The performance of the Village Financial System Operator has a direct and substantial impact on the Village Welfare Level. Additionally, the Supply Chain has a direct and substantial impact on the Performance of Village Financial System Operators and the Village Welfare Level; The performance of the Village Financial System Operator is able to partially mediate Supply Chain and Knowledge-Oriented Leadership on the Level of Village Welfare in Pringsewu Regency, Lampung Province, Indonesia, because the independent variable is able to significantly influence both directly and indirectly the dependent variable.
Exploring the relationship between sustainable supply chain and sustainable development goals on the financial performance of SMEs
Authors: Rismawati Rismawati , Darsono Tri , Pujotomo Darminto , Tunjungsari Hetty Karunia , Numberi Agustinus , Korniawan Rostamaji , Slamet Bejo , Agustiyanto Agustiyanto
Published: April 2024

This research aims to analyze the relationship between sustainable supply chains on financial performance, Sustainable Development Goals (SDGs) financial performance and Sustainable supply chains on Sustainable Development Goals (SDGs). This research uses a quantitative survey method, research data was obtained by distributing online questionnaires through media social to 390 respondents belonging to SMEs, and respondents were determined using the simple random sampling method. Data analysis used Structural Equation Modeling (SEM) Partial Least Square (PLS) with data processing tools using SmartPLS 3.0 software. The questionnaire was designed using a Likert scale of 1 to 7. The independent variable in this research is the sustainable supply chain, the mediating variable is Sustainable Development Goals (SDGs) and the dependent variable is financial performance. The stages of data analysis are validity and reliability testing, significance or hypothesis testing, and mediation influence testing. The results of data analysis show that the Sustainable supply chain has a positive and significant relationship to financial performance, Sustainable Development Goals (SDGs) have a positive and significant relationship to financial performance and the Sustainable supply chain has a positive and significant relationship to Sustainable Development Goals (SDGs). To improve the financial performance of SMEs, they must implement a sustainable supply chain in their supply chain, namely from supplier to customer. To improve the financial performance of SMEs, they must implement Sustainable Development Goals (SDGs) in their management system. Implementing sustainability in the supply chain is important to increase operational efficiency and reduce negative impacts on the environment and society.
The role of artificial intelligence on digital supply chain in industrial companies mediating effect of operational efficiency
Authors: Sharabati Abdel-Aziz Ahmad , Awawdeh Heba Ziad , Sabra Samer , Shehadeh Hazem Khaled , Allahham Mahmoud , Ali Ahmad
Published: April 2024

The research aims to investigate the potential impact of Artificial Intelligence (AI) on the digital supply chain in light of extant literature on the Decision-Oriented Information (DOI) theory and the Technology-Oriented Enterprise (TOE) framework. The research further attempts to unpack the strategic implications of AI integration in supply chain management, and its association with operational excellence and business model innovation. The study is exploratory and employs a mixed-methods approach. We develop propositions that examine the decision-making processes within AI-enhanced supply chains based on an analysis of concepts central to the DOI theory. We also employ the TOE framework to develop further propositions regarding the technological infrastructure required for AI implementation. Empirical case studies encompassing AI applications in different industries (e.g. manufacturing, healthcare, and pharmaceuticals) are presented to gain a broad perspective of the impact of AI on the digital supply chain. AI technologies inherently make supply chains more agile, transparent, and responsive. Machine Learning algorithms allow for more accurate forecasting and demand management under conditions of supply chain risk and volatility. Robotics and automation, allow for greater flexibility and efficiency in executing operations and logistics. Additionally, the successful implementation of AI is heavily contingent on the organization’s current level of technological infrastructure and its alignment with its current and future business objectives. Furthermore, the DOI theory and TOE framework may serve as a blueprint for how one could evaluate AI implementation beyond the scope of supply chain management.
The role of collaborative competitiveness marketing tourism towards sustainable competitive advantage in creative industries in the VUCA era
Authors: Bushairi Siti Aliyati Al , Sularso R. Andi , Tobing Diana Sulianti K , Irawan Bambang
Published: April 2024

This study examines the influence of strategic flexibility, innovation culture, agility, ambidexterity, and open innovation on sustainable competitive advantage, with corporate innovation and collaborative marketing tourism competitiveness as mediating variables. Data was collected directly through structured interviews guided by questionnaires. The research population was 534 registered "craft" creative industry companies including pearls, "Sasak" ikat weaving, and pottery in West Nusa Tenggara Province, Indonesia with the analysis unit being managers or assistant managers. The sampling method used stratified proportional random sampling with a sample size of 240 respondents. Data analysis in this study used descriptive statistics and Covariance-based SEM (Amos software). The findings prove that the eleven hypotheses which stated that there was a direct influence of the variables studied were all confirmed. Strategic flexibility and a culture of innovation play a role in increasing company innovation. Strategic flexibility plays a role in increasing the collaborative competitiveness of marketing tourism. Agility, ambidexterity, and open innovation play a role in increasing sustainable competitive advantage. Corporate innovation and collaborative competitiveness marketing tourism play a role in increasing sustainable competitive advantage. These results are very important to fill the research gap regarding the factors supporting innovation and collaborative competitiveness marketing tourism, and sustainable competitive advantage in Indonesia.
The moderation of trust on the relationship between TOE factors and generalized audit software usage and financial performance
Authors: Marei Ahmad
Published: April 2024

The importance of Generalized Audit Software (GAS) is particularly important for nations' development. Picking 'Over Conduct Theorized Results and Consequences' Poly GAS as a test subject, results have been inconsistent in previous studies on predictor variables and consequences of using GAS. This study aims to investigate the predictors and consequences of using GAS. From the perspective of Resource-oriented technology (Approach (TOE) fitness - View (RBV Environment), It is intended that technology's relative advantage, compatibility, and complexity, as well as organizational readiness top management support IS committee) Villa have an important influence on GAS, which in turn is expected to affect financial performance. Trust will serve as a moderating variable between technological and organizational factors, and GAS. Profession MB. This counts all audit firms in Jordan. The research questionnaire was distributed by purposive sampling for subsequent investigation. As many as 210 valid questionnaires out of all completed questionnaires were gathered from this study by using Smart PLS as the data analysis software. Technological relative advantage, compatibility, and complexity as well as organizational readiness (top management and organizational readiness) have a significant effect on GAS which in turn affects financial performance. Accepted Southern Trustor did not affect the impact of technology and organization factors in GAS. So, the results can provide some ideas to policymakers in Jordan about how to foster the use of GAS to improve financial performance and bring down the new technology adoption costs.
The association between CEO characteristics and privileges and the extent of firms’ sustainability disclosure: The role of board independence
Authors: Azzam Mohammad
Published: April 2024

The literature argues that the quality of a firm’s financial reporting is reflected in the extent of its sustainability disclosure (SD). This study therefore examines the link between CEO characteristics (i.e., age, financial experience, duality leadership structure) and privileges (i.e., compensation and ownership) and the extent of SD. It also examines whether board independence has a vital impact on this association. A panel data set of 329 firm-year observations of firms listed on the Amman stock Exchange (ASE) between 2022 and 2023 is investigated. While the results show that a CEO’s age and compensation positively and significantly affect the magnitude of a firm’s SD, the CEO’s financial experience, duality and ownership do not have a significant link to SD. Moreover, when board independence moderates the association between CEO characteristics and privileges and the extent of SD, the only variable that has a positive and significant effect on the extent of sustainability information is the CEO’s age. The findings are expected to be beneficial to firms’ decision makers regarding the selection of CEOs, as well as in deciding their compensation schemes. It also adds new evidence to the current debate in the literature on this issue, especially from a developing capital market like Jordan.
Brand image and customer behavior in container food courts: The role of social media content and generational differences in Indonesia
Authors: Sutia Sabar , Fahlevi Mochammad
Published: April 2024

This study examines the impact of Social Media Advertising Content (SMAC) and Social Media Sales Promotion Content (SMSPC) on Brand Image (BI) and customer behavior (CB) within the emergent context of container food courts in Indonesia. Focusing on Jakarta and Surabaya, which are cities at the forefront of culinary innovation, this study aims to uncover how digital marketing practices shape consumer perceptions and behaviors in this novel sector. The study employed rigorous methodology, including G*Power for sample size determination and SmartPLS for data analysis, and engaged 292 participants through a carefully designed survey. The findings indicated significant relationships between SMAC and SMSPC on BI, and subsequently on CB, underscoring the critical role of social media content in enhancing BI and shaping CB. Additionally, this study examines the generational differences between Generation Y and Generation Z, offering insights into tailored marketing strategies that cater to their distinct preferences. This study enriches academic discourse on the impact of digital marketing in the food industry and provides practical recommendations for practitioners aiming to leverage social media to enhance BI and foster positive CB in container food courts. The insights gained from this study not only illuminate the dynamics of social media marketing in an Indonesian context but also suggest avenues for future research in an ever-evolving digital landscape.
I-deals on the retention of human talent in health networks in Satipo, Peru
Authors: Yance Hansel Renato Puente , Prado Rosibel Amparo Arauco , Vicente-Ramos Wagner
Published: April 2024

The objective of the research was to determine if there is an influence of i-deals on the retention of human talent in the health networks of Satipo, Peru. The study was carried out from a quantitative approach, with a correlational-non-experimental-translational design. A questionnaire was administered to 308 workers who negotiated one or more idiosyncratic agreements between December 2023 and February 2024. Using the structural equation model, it was obtained that the i-deals of work content (i-TC) and development (i-D) have a higher level of influence on the retention of human talent (p <0.05), generating a high commitment to the organization; based on the appropriate job assignment to employees according to technical and soft skills, and aligned with their personal interests. On the other hand, flexibility (i-F) and financial (i-FI) i-deals do not influence the retention of human talent, because the remuneration is not aligned with the required professional skills. It is concluded that for the public health sector, employees prefer to have autonomy in the way they perform their work, opportunities for professional specialization rather than financial incentives.
Histopathology of the Midgut (Longitudinal section) of Aedes aegypti larvae after exposure to kaffir lime leaf extract from Bali, Indonesia
Authors: Adrianto Hebert , Rambung Etha , Silitonga Hanna Tabita Hasianna
Published: April 2024

Various countries have reported the resistance of mosquitoes to synthetic insecticides and larvicides. Scientists take advantage of secondary metabolites from plants and develop them into natural larvicides. Kaffir lime leaves (Citrus hystrix) as a cooking spice is of concern in this study. The main aim of this study was to identify differences in midgut histopathological changes in Ae. aegypti larvae after exposure to C. hystrix leaf extract. This research is experimental research in the laboratory. There are five treatments with three replications. Then, 20 third-instar Ae. aegypti larvae were placed into each plastic container and recorded for 24 hours. Histopathological slices of the larval midgut were produced and stained with hematoxylin and eosin (HE). A light microscope was used to identify it. Data on changes in midgut larvae were analyzed using SPSS. Mortality of the larvae was shown in C. hystrix extract groups at doses of 1,500 and 3,500 ppm. Midgut changes occur in the length of the midgut lumen, the length of the epithelium, and the loss of the epithelial cell nucleus. The cell nuclei were not visible in the extract group at a dose of 3,500 ppm. The statistical test showed that there are differences in midgut histopathological changes in Ae. aegypti larvae after exposure to C. hystrix leaf extract. We need an in-depth study of the potency of the extract C. hystrix as an alternative larvicide against Ae. aegypti for the future.
Evaluation of Antidiabetic Activity of Methanolic Leaf Extract of Nephelium lappaceum L. against Streptozotocin-Nicotinamide Induced Type-II Diabetes in Wistar Albino Rats
Authors: A Abarnadevika , T Mathuraveendran , G Ariharasivakumar , R Srinidhi
Published: April 2024

Leaves of Nephelium lappaceum L. Family Sapindaceae has been traditionally used in many Asian countries for several therapeutic purposes. However, the antidiabetic activity of leaf has not been scientifically investigated so far. The aim of this study therefore, was to evaluate the antidiabetic activity of methanolic leaf extract of Nephelium lappaceum (MLEN) against streptozotocin (STZ) - nicotinamide (NIC) induced type II diabetes in albino rats. Non-insulin dependent diabetes mellitus was induced in overnight fasted rats by a single intraperitoneal injection of 60mg/kg streptozotocin 15min after the i.p administration of 120mg/kg of nicotinamide. The diabetic rats were treated with 28 days by the oral administration of methanolic leaf extract of Nephelium lappaceum L. (400 and 800mg/kg/b.w). In glucose to tolerance test, MLEN markedly reduced the external glucose load. Fasting blood glucose level, body weight were monitored every 7 days during the treatment. At the end of the study fasting blood glucose level, haemoglobin, HbA1c, kidney (urea, creatinine) functional test, liver (SGOT, SGPT) functional test and in vivo antioxidant markers (GSH, CAT, SOD, Vitamin C and LPO) were estimated. Histopathology of pancreas was carried out to assess antidiabetic effect of MLEN. After treatment with MLEN fasting blood glucose, HbA1c levels, SGOT, SGPT and LPO were significantly decreased in diabetic rats. However, haemoglobin, CAT and GSH levels were significantly increased in MLEN treated diabetic rats. The histopathological study of the pancreas in extract treated diabetic group’s revealed regeneration of beta cells. The methanolic leaf extract of Nephelium lappaceum L. was evaluated for its effect on blood sugar, against the STZ –NIC induced diabetic rats and compared it with standard drug metformin. The result of this experimental study concluded that MLEN of Nephelium lappaceum L. leaves possess safe and strong antidiabetic activity against STZ-NIC induced diabetic rats.
Perspectives on Transdermal Drug Delivery System: A Review
Authors: S Vani , N Venkatesan , SB Chandrasekar , C Sreedhar , Pawar Anil T
Published: April 2024

Drug delivery system (DDS) is a collective term used for techniques that carry drugs into or throughout the body for administration and distribution of drug substances to the target cells, specific tissues or desired organs, to exert optimal effects. Among various routes of DDS, the transdermal drug delivery system (TDDS) forms an attractive approach compared to other routes of administration in terms of easy application, non-invasive, avoiding first pass metabolism, for systemic / local effect, directly reaches blood stream, target drug delivery, controlled release of the drug, easy termination of drug action by removing the patch, suitable for geriatric, paediatric subjects, unconscious patients, enhanced subject compliance and decreased side effects and inter and intra-patient variability as well. In this review, we focused on physiology of skin, routes of percutaneous absorption and types of TDDS, design, development and formulation approaches, basic elements, pharmacokinetics, factors affecting drug penetration, characterization and its evaluation. Significant discussion of their specific advantages, benefits especially in pain management, clinical considerations, general guidelines for using TDDS, market demand etc. This article also provides valuable literature for suitability of most of the Non-steroidal anti-inflammatory drugs (NSAIDs) for transdermal administration mainly due to their pharmacological aspects. In recent years, the scope of TDDS has increased in national as well as foreign market. Hence there are increased research activities from many pharma companies and research institutes for potential drug candidates for TDDS. The promising response of transdermal patches has spurred further research and development in this area. The global transdermal patch pipeline is overflowing, pointing to a bright future for these patches in the coming years. Therefore, TDDS may be the best alternative to oral formulations for effective treatment of inflammatory conditions.
ENVIRONMENTAL IMPACT ASSESSMENT OF DISINFECTANTS
Authors: KOMAROV M. , POSPELOV A. , KOROB N. , KHOTKO A.
Published: April 2024

Today, a wide range of disinfectants are used in the world. According to their chemical nature, they are organic and inorganic. Each of the disinfectants has its own advantages and disadvantages. In this article, we analyzed the environmental impact of five different disinfectants: sodium hypochlorite, calcium hypochlorite, bleach, chloramine and, as an alternative, a solution of ozone in water. The range of life cycle stages to be analyzed included: production/synthesis of a disinfectant, preliminary preparation of a working solution, and disinfection procedure. Each stage is characterized by a number of indicators: raw materials, energy costs, auxiliary substances, emissions, discharges, waste generation. The final comparison of the environmental impact of the selected disinfectants was carried out in the SimaPro software. The assessment results show that bleach and calcium hypochlorite have the greatest impact on the environment. The use of aqueous solutions of ozone has the least impact on the components of the natural environment.
Understanding ‘Insanity’ in Literature as a Case Study and Philosophical Counseling as Emerging Therapy
Authors: Dr. Richa Shukla
Published: April 2024

This article is an attempt is to understand insanity, melancholy, madness, sorrow as the offshoots of gender discrimination and stereotype roles prevailing in the society. Such issues, being claimed as the subject of clinical psychology, have been analyzed popularly from the Freudian point of view, but in this paper, the researcher endeavors to philosophize the issue of insanity and attempts to offer a kind of solution to the problem which seems more ethical and moral in nature. The researcher proposes ‘philosophical counseling’ as an active practice to avoid such mental conditions. Since the study focuses on the gender-biased understanding of insanity, researcher will choose only women as the case of study. It is usually suggested by the scholars such as Terry Eagleton (in Literary Theory: An Introduction) and Edward Said (in his seminal work, Orientalism) that any literary work has to be studied and interpreted in its appropriate socio-cultural and intellectual background.
Challenging fun: Predicting customers’ sustained interest in co-creation through enjoyment
Authors: Szu-Yu Chou Szu-Yu Chou , Szu-Yu Chou Yi-Chia Wu , Yi-Chia Wu Ching-Ju Chen
Published: April 2024

Numerous enterprises engage in the advancement of product or service innovation by actively involving consumers in the co-creation process. This study aims to examine the significance of co-creation enjoyment in fostering sustained customer co-creation, particularly in situations involving increased task difficulty. A total of 274 valid questionnaires were collected from participants who had engaged in various types of co-creation activities, such as ideation, design, support, and marketing. Three findings were unfolded: First, both utilitarian and hedonic value positively affect customers’ sustained interest in co-creation. Second, enjoyment in co-creation serves as a mediating factor between customers’ perceived value and sustained interest. Third, engaging in challenging tasks strengthens the positive relationship between utilitarian value and co-creation enjoyment. This insight is particularly relevant in the context of developing innovation strategies by fostering sustainable customer engagement.

 
La profilassi dell'infezione da virus respiratorio sinciziale: dal dire al fare?
Authors: Marchetti Federico
Published: April 2024

Alcuni stati europei hanno introdotto la prevenzione universale con il nirsevimab con risultati favorevoli, così come dimostrerebbe l’esperienza pilota della Valle d’Aosta (pag. 239). Si tratta di definire in modo molto pratico cosa fare nel panorama “nazionale” per la prossima stagione.
Ipospadia
Authors: Vrinceanu Adelina Mihaela , Barbi Egidio , Scarpa Maria-Grazie , Olenik Damiana , Iaquinto Marianna
Published: April 2024

We report a clinical case of a boy who underwent surgery for proximal hypospadia and developed postoperative complications. We then briefly summarize the current knowledge about hypospadias, addressed to pediatricians and other non-surgical professionals.
Screening per diabete mellito tipo 1 e celiachia: intenzioni, pregi e difetti
Authors: Tornese Gianluca , Greco Luigi
Published: April 2024

Italy is the first country in the world to have introduced screening on the entire pediatric population for type 1 diabetes mellitus and celiac disease which will be preceded by a preparatory pilot study in 4 regions and on approximately 5000 children aged 2, 6 and 10 years of age. In this article we will give some practical information on screening and we will try to give the reasons for screening and any doubts, keeping in mind the Wilson and Jungner screening criteria.
Exploring Sociolinguistic Dimensions: Analysing Sociolinguistic Elements In The selected Literary Texts
Authors: Mittal Swati , Vashist Dr. Shivani , Chaudhary Dr. Kajal
Published: April 2024

Each language harbours historical, cultural, and social connotations, contributing to the layers of meaning within the narrative. Sociolinguistics studies how language and society interact, a topic covered in various literary works that examine dialects, the intricacies of communication, and the impact of language on individuals and groups. The study of language interacts with social factors, and sociolinguistics is the intersection of linguistics and sociology. Sociolinguistics, a multidisciplinary field, provides a rich framework for comprehending language dynamics in various social contexts. This study aims to investigate the representation of critical elements such as register, polyglossia, diglossia, code-switching, lexical borrowing, bilingualism, trilingualism, code-switching, and language planning in literary narratives. Through closely examining selected novels, this paper investigates how authors employ linguistic diversity as a narrative tool, mirroring societal norms, cultural identities, power dynamics, and intergroup communication. This research aims to contribute to a more in-depth understanding of language's role in shaping fictional worlds and reflecting real-world linguistic complexities by investigating the interplay between sociolinguistic concepts and literary expression.
Strengthening Emotional Intelligence and Work Discipline to Improve Principal Performance in Indonesia
Authors: Rahayuningsih Taty , Setyaningsih Sri , Sunardi Oding
Published: April 2024

Personal competence is the basis for efforts to improve the quality of education management for principals. This research aims to determine the strength of the emotional intelligence and work discipline variables that were considered to affect the principal performance in Indonesia. The research design was path analysis followed by the SITOREM method. The research sample consisted of 198 certified private junior high school principals. The sampling technique employed was Multistage Random Sampling. The research instrument was a questionnaire that had been tested for validity and reliability. This quantitative research data analysis technique consisted of descriptive statistical analysis, data analysis requirements testing, inferential statistical analysis, regression analysis, and hypothesis testing. The research results obtained that: (1) the hypothesis of Emotional Intelligence (X1) on principal performance (Y) resulted in a path coefficient of 0.125, which implied that a conclusion had a direct positive effect; (2) the work discipline hypothesis (X2) on principal performance (Y) obtained a path coefficient of 0.271, which implied a conclusion had a positive direct effect; (3) there was an indirect effect of emotional intelligence and work discipline on principal performance with a path coefficient of 0.046 < 0.125. The research conclusion reported that emotional intelligence and work discipline positively affected junior high school principals’ performance.
ԲԻԶՆԵՍԻ ՀՈԳԵԲԱՆՈՒԹՅՈՒՆ. ԿԱՄ՝ ՁԵՌՆԱՐԿԱՏԻՐՈՒԹՅԱՆ ՎԱՐՄԱՆ ՆՈՐ ԿԱՆՈՆՆԵՐ ՏՆՏԵՍԱԿԱՆ ՀԱՆՑԱԳՈՐԾՈՒԹՅՈՒՆՆԵՐԻ ԿԱՆԽԱՐԳԵԼՄԱՆ ՀԱՄԱՏԵՔՍՏՈՒՄ
Authors: Mamikonyan K.H. , Galstyan E.L.
Published: April 2024

Հոդվածում դիտարկվել են տնտեսական հանցագործությունների կանխարգելման համատեքստում ձեռնարկատիրության վարման որոշ սկզբունքային կանոններ, որոնք առավելապես ներկայացվում են բիզնեսի հոգեբանության ոլորտում: Բիզնեսում արդյունավետ կառավարման համակարգի ստեղծումը, կայուն կորպորատիվ վարկանիշը, մրցակցային առավելությունների ձեռք բերումը, հուսալի գործընկերային կապերի ստեղծումը որպես գործոնային վերլուծություն, թեկուզ և ոչ մասնագիտորեն՝ դիտարկվելով հոգեբանության շրջանակներում, տանում է «անձի» դերի բարձրացմանը՝ վերը նշված գործարարության նպատակներին հասնելու համար, ինչպես նաև ձեռնարկատիրական խնդիրների լուծման կամ որոշումների կայացման բարդ իրավիճակների դեպքում անձնական գործողությունների հնարավորինս ուղղորդմանը: «Անձի» դերի բարձրացումը բարոյահոգեբանական առումով պահանջում է նաև պարբերաբար ներդրումներ և շարունակական հետաքրքրություն գործարար միջավայրի վրա իր ազդեցության կատարելագործման նկատմամբ՝ այդպիսով պահանջելով ուսումնասիրությունների առանձին ոլորտ, ինչպիսին է բիզնեսի հոգեբանությունը:
Բանալի բառեր. բիզնես, բիզնեսի հոգեբանություն, տնտեսական հանցագործություններ, ձեռնարկատիրություն, ձեռնարկատիրության վարման կանոններ:
ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ МЕТОДА ТРЕХСТУПЕНЧАТОГО ИЗВЛЕЧЕНИЯ РАСТВОРИТЕЛЯ ИЗ ШТРИХА ЗАПИСИ ДЛЯ УСТАНОВЛЕНИЯ ДАВНОСТИ ВЫПОЛНЕНИЯ РЕКВИЗИТОВ ДОКУМЕНТОВ
Authors: Ivanova E.V. , Aksenova V.I. , Rubizhanskaya L.A.
Published: April 2024

В статье рассмотрены возможности применения в качестве альтернативного метода трехступенчатого извлечения 2-феноксиэтанола (2-ФЭТ) при разных температурах термодесорбции из одного и того же штриха записи, выполненной пастой шариковой ручки, для установления абсолютной давности изготовления документов. Приведены сравнительные результаты установления давности выполнения реквизитов документов по относительному содержанию в штрихах летучих растворителей и с применением трехступенчатого извлечения 2-феноксиэтанола (2-ФЭТ). Оценены результаты применения метода трехступечатой термодесорбции для материалов письма с различным составом связующих и красителей.
Ключевые слова: абсолютная давность, методика, альтернативный метод, термодесорбция.
Preditores de sarcopenia em pacientes com doença renal crônica submetidos à hemodiálise
Authors: Ripardo Katharyna Khauane Brandao , Nogueira Danniel Albuquerque , Lima Rafael Sousa , Santos Paulo Roberto
Published: April 2024

A sarcopenia é uma doença que tem grande impacto na qualidade de vida e na capacidade funcional de pacientes mantidos em diálise. O objetivo desse estudo foi identificar os fatores de risco para desenvolvimento de sarcopenia em paciente com doença renal crônica dialítica. Trata-se de uma pesquisa transversal, realizada no Centro de Hemodiálise de referencia na Região Norte do Ceará no ano de 2023. Participaram 152 pacientes de ambos os sexos, com idade maior que 18 anos.  Para coleta de dados,avaliaram-se o perfil sociodemográfico e a presença de comorbidades, conforme o índice de Khan. Na análise da sarcopenia, utilizou-se do dinamômetro e, para o consumo alimentar, o recordatório alimentar de 24 horas. Os dados foram organizados no Excel e analisados no programa computacional R.Para  análise estatística,realizaram-se a análise univariada e multivariada, considerando o intervalo de confiançade 95% e significância estatística mediante p ≤ 0,05. Apresença de sarcopenia foi em 52% da amostra. Observou-se consumo alimentar inferior às recomendações preconizadas em kcal/kg/dia   e proteina grama/kg/dia. Na análise univariada, pacientes com índice de Khan médio e/ ou alto risco obtiveram trêsvezes mais chance de ter sarcopenia (0,004 P) e pacientes com idade avançada também apresentarammais chances de sarcopenia (<0,001  P). Na análise multivariada, apenas a idade foi preditora de sarcopenia.
Assessing Sustainability in Renewable Energy: Sources, Solutions and Metrics
Authors: Abildtrup Abdulhaq , Alminde Iben Charlotte
Published: April 2024

Renewable energy sources are obtained naturally and have the capacity to surpass normal amounts of energy presently being used. These sources include solar, hydropower, wind, and biomass. The costs of generating electricity vary depending on the technology being applied; with wind energy having the lowest costs and photovoltaics being known to have the highest. Different techniques of renewable energy are faced by particular challenges, such as obstacles during the process of storing energy, and intermittent nature of energy production. Evaluating the sustainable aspect of renewable energy sources necessitates considering factors such as water usage, land usage, and social impacts. Wind energy is typically known as the most sustainable source of energy, with geothermal and hydropower energy being second. This article reviews the capabilities of renewable energy sources, and their significance in achieving sustainable development. It reviews the relevance of technological progress in rendering renewable energy sources cost effective and economically viable. The sources of energy discussed in this article include biomass, solar, wind, and hydropower; discussing their varying dimensions of competitiveness and progress made. In addition, this article contributes to the knowledge of parameters employed in assessing sustainability, including environmental and financial implications connected to different sources of energy. The contributions suggests that the most sustainable energy source is the wind power, followed by geothermal and hydropower. However, it notes that geographical variations may impact the rankings.
تفسیر" التحریر التنویر" کے بلاغی منہج کا تحقیقاتی جائزہ
Authors: Dr. Marvah Iqbal
Published: April 2024

Rhetoric refers to the use of language in speech or writing, especially in speech, with both external and internal qualities. This is such a miraculous aspect of the Qur'an, without the understanding of which it becomes impossible to reach the real meaning and purpose of the divine word. That is why the commentators of every age have adopted the style of rhetorical explanation of the Qur'anic verses while interpreting the Qur'an."Al-Tahrir wa al-Tanwir" is one such rhetorical commentary of the 20th century in which Allama Muhammad al-Tahir Ibn Ashoor has shed light on the rhetorical aspect of the verses in great detail. Therefore, in this article, the rhetorical method of Allama ibn Ashoor's commentary "Al-Tahrir wa al-Tanwir" is presented.