bluuebunny/crossref_metadata_2025 huggingface dataset:
TAWAKAL KEPADA ALLAH DAN IMPLIKASINYA TERHADAP RESILIENSI
Authors: Faruqi Abdullah , Saputra Aryan Muhaimin , Saputri Leonita Ikasari
Published: May 2022

Dalam kehidupan sehari-hari, manusia banyak mengalami tantangan dan masalah. Tantangan tersebut datang dari banyak aspek, baik dalam aspek kehidupan pribadi, sosial, ataupun karir. Tantangan dan masalah tersebut dapat membuat kesehatan mental dan keberfungsian individu menjadi terganggu. Dalam banyak penelitian telah dibuktikan bahwa resiliensi sangat bermanfaat bagi kesehatan mental individu. Beberapa penelitian  menemukan bahwa religiusitas memiliki hubungan dengan resiliensi. Salah satu aspek dari religiusitas adalah tawakal. Literature review ini ingin menunjukkan bagaimana hasil  penelitian-penelitian yang telah dilakukan mengenai hubungan antara tawakal dengan resiliensi. Metode yang digunakan dalam literature review ini adalah studi pustaka. Hasil analisis deskriptif terhadap studi pustaka menemukan bahwa orang yang bertawakal kepada Allah menunjukkan peningkatan positif pada kesehatan mental, keberfungsian, dan resiliensi individu.
Kata kunci: tawakal kepada Allah, surrender to God, resiliensi, kesehatan mental, keberfungsian diri
FENOMENA COPYCAT SUICIDES DAN PERAN PEMBERITAAN MEDIA MASSA YANG BERLEBIHAN TERINSPIRASI DARI SURAH AN-NISA AYAT 29
Authors: Shania Fitri Winda , Hapsari Ayu Widowati Dwi , Poetri Kintan Maharani
Published: May 2022

Seorang selebritas atau public figure memiliki pendukung massa yang besar. Pemberitaan terkait selebritas akan menjadi topik yang ditunggu publik ketika isu-isu mengenainya muncul dipermukaan. Seperti halnya saat seorang selebritas diberitakan melakukan aksi bunuh diri, dampak yang dapat ditimbulkan salah satunya adalah efek werther atau dikenal copycat suicide yaitu fenomena bunuh diri yang dilakukan seseorang akibat pengaruh dari tayangan media yang berlebihan. Bunuh diri menempati urutan ke 15 penyebab kasus kematian global. Penulisan ini bertujuan untuk mencegah terjadinya copycat suicide setelah pemberitaan kematian seseorang melalui pemaafan diri sendiri dalam pandangan islam. Dengan harapan dapat memberikan kontribusi keilmuan mengenai penyebab terpicunya copycat suicide setelah kematian public figure diakibatkan keputusaan dan menyalahkan diri sendiri. Pemaafan merupakan suatu proses menghapus luka atau bekas-bekas luka dalam hati yang merupakan kesediaan diri dalam mengelola emosi, serta senantiasa menyadarkan diri jika rahmat dan kasih sayang Allah Ta’ala memaafkan hambanya lebih besar dari murkanya.
Kata kunci: Bunuh Diri, Media Massa, Pemaafan
SYUKUR DALAM AL-QUR’AN DAN IMPLIKASINYA PADA KESEHATAN MENTAL DI MASA PANDEMI
Authors: Istiqomah Inti , Azhan Aniq
Published: May 2022

Latar Belakang: Islam telah mengajarkan tentang bagaimana konsep bersyukur dalam kehidupan sehari hari. Syukur dapat membantu dalam mengatasi setiap masalah sulit seperti di masa pandemi Covid-19 ini. Pandemi Covid-19 memberikan dampak kesehatan mental yang rendah di masyarakat. Metode: Penelitian ini menggunakan metode narrative review atau studi literatur. Artikel dalam penelitian ini dipilih berdasarkan kesesuaian konteks penelitian yang sedang dilakukan. Artikel dipilih melalui proses penentuan pertanyaan penelitian, pencarian literatur, analisis referensi, dan merumuskan hasil. Tujuan: Studi literatur ini ditujukan untuk mengetahui bagaimana implikasi syukur terhadap kesehatan di masa pandemi. Hasil: Berdasarkan hasil penelitian diperoleh bahwa rasa syukur yang tinggi membuat kesehatan mental yang positif. Kemudian syukur memiliki pengaruh terhadap penurunan emosi negatif (stres dan depresi) dan meningkatkan emosi positif (mampu meningkatkan kepuasan hidup, hubungan sosial, dan menciptakan lingkungan yang positif). Kemudian bersyukur juga dapat memberikan perasaan bahagia, damai dan tenang.
Kata Kunci: Kesehatan Mental, Syukur, Emosi Positif, Emosi Negatif
Genetics, Molecular Control and Clinical Relevance of Habituation Learning
Authors: Blok Laura E.R. , Boon Marina , van Reijmersdal Boyd , Höffler Kira D. , Fenckova Michaela , Schenck Annette
Published: May 2022

Habituation is the most ancient and fundamental form of learning. As a firewall that protects our brain from sensory overload, it is indispensable for higher cognitive processes. Studies in humans and animal models provide a growing body of evidence that habituation is affected in autism and related monogenic neurodevelopmental disorders (NDDs). An integrated application of habituation assessment in NDDs and their animal models has currently unexploited potential for fundamental neuroscience and medical care.With the aim to gain mechanistic insights, we systematically retrieved genes that have been demonstrated in the literature to underlie habituation. We identified 258 evolutionarily conserved genes across species, describe the biological processes they converge on, and highlight regulatory pathways and drugs that may alleviate the habituation deficits associated with their dysregulation. We also summarize current habituation paradigms and extract the most decisive arguments from the literature that support the crucial role of habituation for cognition in health and disease. We conclude that habituation is a conserved, quantitative, cognition- and disease-relevant process that can connect preclinical and clinical work, and hence is a powerful tool to advance research, diagnostics,’’ and treatment of NDDs.
Malnutrition Screening and Assessment
Authors: Serón-Arbeloa Carlos , Labarta-Monzón Lorenzo , Puzo-Foncillas José , Mallor-Bonet Tomas , Lafita-López Alberto , Bueno-Vidales Néstor , Montoro-Huguet Miguel
Published: May 2022

Malnutrition is a serious problem with negative impact on the quality of life and the evolution of our patients, contributing to an increase in morbidity, hospital stay, mortality and health spending. Early identification is fundamental to implement the necessary therapeutic actions involving adequate nutritional support to prevent or reverse malnutrition. This review presents two complementary methods of fighting malnutrition: nutritional screening and nutritional assessment. Nutritional risk screening is conducted using simple, quick-to-perform tools and is the first line of action in detecting at-risk patients. It should be implemented systematically and periodically on admission to hospital or residential care, as well as on an outpatient basis for patients with chronic conditions. Once patients with a nutritional risk have been detected they should undergo a more detailed nutritional assessment to identify and quantify the type and degree of malnutrition. This should include health history and clinical examination, dietary history, anthropometric measurements, evaluation of the degree of aggression determined by the disease, functional assessment and, whenever possible, some method of measuring body composition.
A New Decision Support System for Analyzing Factors of Tornado Related Deaths in Bangladesh
Authors: Sufi Fahim , Alam Edris , Alsulami Musleh
Published: May 2022

Tropical cyclones devastate large areas, take numerous lives and damage extensive property in Bangladesh. Research on landfalling tropical cyclones affecting Bangladesh has primarily focused on events occurring since AD1960 with limited work examining earlier historical records. We rectify this gap by developing a new tornado catalogue that include present and past records of tornados across Bangladesh maximizing use of available sources. Within this new tornado database, 119 records were captured starting from 1838 till 2020 causing 8,735 deaths and 97,868 injuries leaving more than 1,02,776 people affected in total. Moreover, using this new tornado data, we developed an end-to-end system that allows a user to explore and analyze the full range of tornado data on multiple scenarios. The user of this new system can select a date range or search a particular location, and then, all the tornado information along with Artificial Intelligence (AI) based insights within that selected scope would be dynamically presented in a range of devices including iOS, Android, and Windows. Using a set of interactive maps, charts, graphs, and visualizations the user would have a comprehensive understanding of the historical records of Tornados, Cyclones and associated landfalls with detailed data distributions and statistics.
Impact of COVID-19 Infection on Children and Adolescents after Liver Transplantation in a Latin American Reference Center.
Authors: DE FREITAS ALINE FALLEIROS , PUGLIESE RENATA PEREIRA SUSTOVICH , FEIER FLAVIA , MIURA IRENE KAZUE , DANESI VERA LUCIA BAGGIO , OLIVEIRA ELIENE NOVAIS , HIRSCHFELD ADRIANA PORTA , BORGES CRISTIAN BARBIERI , LOBATO JULIANA VIEIRA , PORTA GILDA , SEDA NETO JOAO , FONSECA EDUARDO ANTUNES
Published: May 2022

Background: COVID-19 infection has received the attention of the scientific community due its respiratory manifestations and association with evolution to severe acute respiratory syndrome (SARS-CoV-2). There are few studies characterizing SARS-CoV-2 in pediatric immunocompromised patients, such as liver transplanted (LT) patients.The aim of this study was to analyze the outcomes of the larger cohort of pediatric liver transplant recipients (PLTR) from a single center in Brazil who where contaminated with COVID-19 during the pandemic. Methods: Cross-sectional study. Primary outcomes: COVID-19 severity. The Cox regression method was used to determine independent predictors associated with the outcomes. Results: 74 PLTR were included. Patients were divided into two groups according to the severity of COVID-19 disease: moderate-severe COVID and asymptomatic-mild COVID. Patients categorized as moderate-severe COVID were younger (12.6 months vs. 82.1 months, p 0.03), higher prevalence of transplantation with deceased donor (50% vs. 4.3%, p 0.02) and with a higher prevalence of COVID-infected patients before 6 months after LT (75% vs. 5.7%, p 0.002). The independent predictor of COVID-19 severity identified in the multivariate analysis was COVID-19 infection < 6 months after LT (HR=0.001, 95% CI=0.001-0.67, p 0.03). Conclusion: The time interval of less than 6 months between COVID-19 infection and LT was the only predictor of disease severity in pediatric patients.
Shiftless, A Critical Piece of the Innate Immune Response to Viral Infection
Authors: Rodriguez William , Muller Mandy
Published: May 2022

Since its initial characterization in 2016, the interferon stimulated gene Shiftless (SHFL) has proven to be a critical piece of the innate immune response to viral infection. SHFL expression stringently restricts the replication of multiple DNA, RNA, and retroviruses with an extraordinary diversity of mechanisms that differ from one virus to the next. These inhibitory strategies include the negative regulation of viral RNA stability, translation, and even the manipulation of RNA granule formation during viral infection. Even more surprisingly, SHFL is the first human protein found to directly inhibit the activity of the -1 programmed ribosomal frameshift, a translation recoding strategy utilized across nearly all domains of life and a several human viruses. Recent literature has shown that SHFL expression also significantly impacts viral pathogenesis in mouse models, highlighting its in-vivo efficacy. To help reconcile the many mechanisms by which SHFL restricts viral replication, we provide here a comprehensive review of this complex ISG, its influence over viral RNA fate, and the implications of its functions on the virus-host arms race for control of the cell.
Prison Education in Brazil: State-of-the-Knowledge
Authors: Carneiro Braga Francisco , Euzébio da Rosa Josélia
Published: May 2022

This work presents an overview of recent scientific production on prison education in Brazil. Thereunto, a survey was carried out in the CAPES theses and dissertations catalog, achieving 15 works published in 2019 and 2020. Initially, the main elements of each work (justification, methodology, theoretical references, and results) were analyzed, from which was possible identify convergences and divergences, further most recurrent issues in discussions. Thereby, it was possible identify that analyzed research focused on characterization of prison education in Brazil and its conditions, on experience reports and faced challenges, and on pointing paths to overcome these challenges. The study concludes that in general analyzed research point to limitations that pedagogy in prison system imposes, also identified in non-prison contexts, and proposes a reflection on the relation between the teaching organization system and these limitations.
Duygusal Zekânın Kendini İfade Etme İletişim Becerisine Etkisi: Ön Lisans Öğrencileri Üzerine Bir Araştırma
Authors: BALKAN AKAN Betül
Published: May 2022

Bu araştırmanın amacı, ön lisans okuyan öğrencilerin duygusal zekâ düzeylerinin kendini ifade etme iletişim becerisine etkisini ortaya koymak olarak belirlenmiştir. Ayrıca öğrencilerin duygusal zekâ düzeyleri ve alt boyutları, kendini ifade etme iletişim becerileriyle demografik özellikleri arasında farklılık olup olmadığının araştırılması hedeflenmiştir. Tekirdağ Namık Kemal Üniversitesi Hayrabolu Meslek Yüksekokulunda sosyal bilimler alanındaki bölümlerde okuyan 181 öğrencinin katılımıyla ve anket tekniği yoluyla toplanan veriler SPSS 20 paket programında analiz edilerek yorumlanmıştır. Verilerin analizinde tanımlayıcı istatistikler, açıklayıcı faktör ve güvenirlik analizleri, korelasyon ve regresyon analizleri ile Mann-Whitney U testi yapılmıştır. Araştırma sonuçlarına göre; ön lisans öğrencilerinin duygusal zekâ düzeylerinin kendini ifade etme iletişim becerisini anlamlı ve pozitif yönde etkilediği; duygusal zekâ ile alt boyutları olan kendi duygularını değerlendirme, duyguların kullanılmasına ilişkin alt boyutları ile öğrencilerin iletişim dersi alma durumları arasında ve kendini ifade etme iletişim becerisi ile cinsiyet, sınıf ve iletişim dersi alma durumu açısından farklılık gösterdiği görülmektedir. Dolayısıyla duygusal zekâsı yüksek bireylerin kendini daha iyi ifade edebilme iletişim becerisine sahip oldukları sonucuna ulaşılmıştır.
Financial Impacts of Covid-19 Pandemic for Turkish Public Hospitals
Authors: KÜÇÜK Aziz
Published: May 2022

The aim of the study is to assess financial implications of Covid-19 pandemic on Turkish public hospitals and to discuss Turkish government's responses. A comparative analysis is carried out with the medical and financial data of Turkish public hospitals between March-December 2019 and March-December 2020. Outpatient services decreased by approximately 49%, inpatient admissions dropped by %35. Due to this decrease in the number of patients, outpatient revenues decreased by 37.8%, while inpatient revenues increased by 6.3% thanks to reimbursement supports by the Social Security Institution (SSI). On the other hand, total hospital expenses increased by 24% with the impact of Covid-19-related expenses. This increase is largely caused by performance-based supplementary payments, drugs, and operating expenses. Prospective global budget model helps healthcare financing stability for Turkish public hospitals. Public hospitals receive their global budgets to compensate for revenue shortfalls. The SSI also try to compensate the financial losses of public and private hospitals with additional reimbursement supports. However, policymakers and managers should prepare for the change of paradigm in the healthcare system and should concentrate to cost-effective policies (such as tele-health services) in hospitals as a result of Covid-19 demands.
Rock Unloading Failure Precursor Based on Acoustic Emission Parametric Fractal Characteristics
Authors: Yang Rui , Jiakun Lv , Zhou Bo , Ma Depeng
Published: May 2022

The mechanical response characteristics and occurrence mechanism of coal and rock under unloading conditions are key to evaluating the stability and control of engineering rock excavation. Triaxial unloading confining pressure tests of coal and rock based on different unloading rates and different initial confining pressure conditions were conducted with fractal theory, research into the fractal characteristics of coal and rock acoustic emission time series under an unloading confining pressure, and the correlations with the unloading failure of coal and rock. The correlation dimension of the acoustic emission signal showed a variation law of a sudden increase, followed by a decrease, increase, and continuous decrease during the experiment. The average time differences between the time when the correlation dimension of coal and sandstone decreased and the actual fracture time of the rock sample were 13.6 s and 16.7 s, respectively. The change in correlation dimension showed the change in internal damage and fracture of the rock sample during the test. The HURST exponent of the acoustic emission time series was calculated at the beginning of the loading. The HURST index showed an overall stable trend and fluctuated around 0.5. A sudden drop in the HURST index resulted when the axial load reached 85% of the peak stress of the rock sample. When the HURST index dropped suddenly (minimum less than 0.2) and then increased rapidly (maximum above 0.8), the rock sample was close to rupture. A HURST index of 0.8 can be used as an index of rock sample unloading and fracture.
Physiologically-Based Pharmacokinetic Model for Pulmonary Disposition of Protein Therapeutics in Humans
Authors: Jagdale Prabhas , Sepp Armin , Shah Dhaval K.
Published: May 2022

Lung related disorders like COPD and Asthma, as well as various infectious diseases, form a major therapeutic area which would benefit from a predictive and adaptable mathematical model for describing pulmonary disposition of biological modalities. In this study we fill that gap by extending the cross-species two-pore physiologically-based pharmacokinetic (PBPK) platform with more detailed respiratory tract that includes the airways and alveolar space with epithelial lining fluid. We parameterize the paracellular and FcRn-facilitated exchange pathways between the epithelial lining fluid and lung interstitial space by building a mechanistic model for the exchange between the two. The optimized two-pore PBPK model described pulmonary exposure of several systemically dosed mAbs for which data is available and is also in agreement with the observed levels of endogenous IgG and albumin. The proposed framework can be used to assess pharmacokinetics of new lung-targeting biologic therapies and guide their dosing to achieve desired exposure at the pulmonary site-of-action.
Improving Containerized Nursery Crop Sustainability: Effects of Conservation-driven Adaptations in Soilless Substrate and Water Use on Plant Growth and Soil-borne Disease Development
Authors: Beaulieu Justine , Belayneh Bruk , Lea-Cox John D. , Swett Cassandra L.
Published: May 2022

Containerized crop production faces increasing sustainability challenges with both soilless substrate and water use. To facilitate use of sustainable practices, we evaluated plant health impacts of two substrates, bark and wood fiber, which we contrasted with peat, a substrate that is slower to renew; this was overlaid with an analysis of the effects of water-saving–targeted irrigation reductions, compared with typical well-watered conditions. Health impacts were evaluated in two crops, considering both physiological and disease impacts for tomato with and without Phytophthora capsici, and chrysanthemum with and without Phytopythium helicoides. Substrate type was a strong determinant of plant health, wherein crops grown in a HydraFiber-peat mix (“fiber”) performed worse than those in bark and peat, with up to a 50% and 45% reduction in shoot biomass in tomato and chrysanthemum, respectively (P < 0.001). Tomato decline incidence from P. capsici was 3–6 times higher in fiber than other substrates, and fiber was the only substrate where the effect of P. capsici enhanced decline and rot development compared with noninoculated plants (P < 0.05). In bark, reduced irrigation consistently inhibited tomato and chrysanthemum growth and shoot water content (typically P < 0.001). In peat, whereas tomato growth was inhibited under reduced irrigation (P = 0.012–0.013), chrysanthemum growth was often unaffected. Growth in fiber was uniformly poor regardless of irrigation regime for both crops, and an irrigation treatment effect was not typically apparent. Reduced irrigation enhanced pathogen effects in fiber and peat for tomato and fiber and bark for chrysanthemum (P < 0.05). This is perhaps the first study to evaluate HydraFiber interactions with disease and reduced irrigation and suggests that this product consistently incurs costs to crop productivity. However, the peat-replacing bark substrate has strong potential to optimize plant growth physiologically and via disease suppression and can be used under reduced irrigation without compromising economic productivity of the system.
The Effect of the Method of Airway Management During Endoscopic Sinus Surgery Procedures on the Intraoperative Bleeding
Authors: Pavlov V. E. , Polushin Yu. S. , Kolotilov L. V. , Karpishchenko S. A.
Published: May 2022

The objective: to conduct a comparative assessment of the severity of intraoperative bleeding with different methods of airway management (using a laryngeal mask and endotracheal tube) during endoscopic rhinosinussurgical procedures.Subjects and Methods. A prospective randomized cohort single-center study of 160 cases of endoscopic rhinosinussurgical procedures under general anesthesia was conducted.Tracheal intubation (TI) was used in 79 cases (Group 1), a laryngeal mask (LM) – in 81 (Group 2). The evaluation criteria in the groups included the bleeding intensity (BI) by 6-point scale of average categories (Fromme-Boezaart Score), indicators characterizing the state of blood circulation during surgery: HR, BPsys., BPdiast., MAP, and perfusion index.Results. Significantly lower BI values were observed in Group 2 at all time points of the study (at the 10th, 30th and 60th minute of surgery). This was due both to using a laryngeal mask, and to lower HR, BPsys., BPdiast, and MAP.Conclusion. The use of a laryngeal mask for airway management during general anesthesia in endoscopic rhinosinussurgical procedures helps to reduce the intensity of surgical field bleeding.
Some Aspects of Postoperative Management of Patients with Ovarian Cancer after Cytoreductive Surgery Using Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Authors: Morikov D. D. , Gorbachev V. I. , Pavlov A. G. , Dvornichenko V. V. , Shelekhov A. V. , Morikov N. D. , Radostev S. I.
Published: May 2022

The objective. Analysis of the course of the postoperative period and number of complications in patients with ovarian cancer during cytoreductive operations with hyperthermic intraoperative intra-abdominal chemotherapy.Subjects and Methods. We assessed the number of bed-days, the volume of infusion-transfusion therapy, diuresis, the volume of enteral feeding, the level of leukocytes, urea, creatinine, and lipocalin associated with gel in 45 patients with ovarian cancer after cytoreductive surgery with hyperthermic intraoperative intra-abdominal chemotherapy.Results. All patients developed polyuria while reference parameters of urea and creatinine were stable. Due to these changes, additional markers of acute renal damage were searched for. 15.9% of cases developed leukopenia on days 7–10. The number of complications and deaths does not exceed the world level.Conclusion. A multicomponent and versatile approach to the postoperative management of patients allows minimizing the level of complications and deaths. A search for a more sensitive marker of acute kidney injury is needed.
Epidural Anesthesia in Abdominal Surgery
Authors: Smolin N. S. , Khrapov K. N.
Published: May 2022

The epidural anesthesia has found widespread application in abdominal surgical interventions. But the relevance of its use is the subject to some doubt and discussion in connection with developing surgical technologies and reduction of the degree of surgical aggression, and introduction of new approaches to the management of patients in the perioperative period. Often the risks of epidural anesthesia exceed expected benefits. This is a limiting factor for its use. Today, there is no uniform approach to the way epidural analgesia is administered in the intraoperative period. However, there is a correlation between the frequency of adverse events related to epidural block and the route of administration (speed of administration, volume, and concentration).Therefore, selecting the optimal method of epidural analgesia within the framework of combined anesthesia can minimize the risks and maximize its positive effects in abdominal surgery.
2-Group symmetries in class S
Authors: Bhardwaj Lakshya
Published: May 2022

2-group symmetries are generalized symmetries that arise when 1-form
and 0-form symmetries mix with each other. We uncover the existence of a
class of 2-group symmetries in general 4d4d\mathcal{N}=2𝒩=2
theories of Class S that can be constructed by compactifying
6d6d\mathcal{N}=(2,0)𝒩=(2,0)
SCFTs on Riemann surfaces carrying arbitrary regular punctures and
outer-automorphism twist lines. The 2-group structure can be captured in
terms of equivalence classes of line defects plus flavor Wilson lines,
which can be thought of as accounting for screening of line defects
while keeping track of flavor charges. We describe a method for
computing these equivalence classes for a general Class S theory using
the data on the Riemman surface used for compactifying its parent
6d6d\mathcal{N}=(2,0)𝒩=(2,0)
theory.
Investigation of the effect of demagnetization fault at Line Start AF-PMSM with FEM
Authors: EKER Mustafa , ÖZSOY Mustafa
Published: May 2022

In motors containing magnets, irreversible demagnetization failure is one of the factors that negatively affect motor performance. In this study, the traditional Axial Flux Permanent Magnet Synchronous Motor (AF-PMSM) rotor structure was changed and the structure that gained the feature of starting from the line was used. Line Start AF-PMSM with 5.5 kW shaft power has 4 poles and each pole consists of 5 magnets. Demagnetization failure was obtained by the flux values of the magnets in any pole are drawn to zero and virtual demagnetization failure is created at certain rates (20%, 40% and 60%). With FEM, the data of the healthy and faulty motor were obtained. The data are then presented comparatively. Obtained data showed that demagnetization fault in Line Start AF-PMSM negatively affects motor performance, and the results are given in detail in the article. The original aspect of the study is that the demagnetization fault in Line Start AF-PMSM was investigated for the first time with FEM.
Nonlinear dynamic analysis and defect detection of gears
Authors: Er-raoudi M. , Diany M. , Aissaoui H. , Mabrouki M.
Published: May 2022

In the current work, the nonlinear dynamic behavior of an eight degrees of freedom gear system is investigated. Tooth crack is introduced into the model. The main sources of excitation are the time varying mesh stiffness (TVMS), time varying mesh damping, backlash and friction inter teeth. By using the potential energy method applied into the cantilevered beam, the TVMS is calculated. The backlash is considered as a dead zone. The effect of backlash, friction and tooth crack on the vibration frequencies is highlighted. The crack detection is based on the time-frequency analysis.
A new signal processing-based approach for detection and localization of defective rolling-element bearing
Authors: Ratni Azeddine , Benazzouz Djamel
Published: May 2022

The signal processing techniques are basically used for the detection of defect in the rotating machines. However, none of the existing approaches consider their localizations especially in gearbox systems where the bearings have the same fundamental characteristic frequencies. In this paper, a novel approach of an analytical Higher-order spectral analysis -based signal processing is investigated to potentially locate the defective rolling-element bearing in the gearbox system. In order to efficiently analyze the vibration signal from bearings for defect detection, experimental studies have shown that the Fast-kurtogram is the most suitable for this purpose. For this reason, we propose a new operation of the Higher-order spectral analysis in order to have both information detection and the localization of the existing defect. This proposed technique offers effective results in terms of detecting and locating the defective bearing.
Reabilitação Respiratória para pacientes submetidos à cirurgia torácica e abdominal
Authors: Nunes Simony Fabíola Lopes , Pascoal Lívia Maia , Lima Neto Pedro Martins , Santos Francisco Dimitre Rodrigo Pereira , Goiabeira Yara Nayá Lopes de Andrade , Santana Anderson Gomes Nascimento
Published: May 2022

Objetivo: descrever a experiência relacionada a reabilitação respiratória para pacientes submetidos à cirurgia torácica e abdominal superior durante a execução de um programa de extensão universitária. Método: relato de experiência, com abordagem descritiva, sobre a criação de um programa interdisciplinar de reabilitação respiratória para pacientes submetidos à cirurgia torácica e abdominal superior com parceria entre universidade pública e hospital municipal de Imperatriz, Maranhão. Resultados: as atividades do programa universitário de reabilitação respiratória para pacientes em pós-operatório são desempenhadas em três eixos in locus: Educação em Exercícios Respiratórios, Capacitação sobre assistência de enfermagem no pós-operatório de cirurgias torácicas e abdominais e, Educação em saúde e intervenções de enfermagem na atenção ao paciente no período pós-operatório. Conclusão: a atuação em projeto respiratório interdisciplinar, focado em ações educativas, mostrou-se uma ferramenta inovadora de apoio ao cuidado clínico de pacientes submetidos à cirurgia torácica e abdominal superior.
Can we Succeed in the Fight Against SARS-CoV-2 with its Emerging New Variants?
Authors: Tavakol Shima , Tavakol Hani , Alavijeh Mo S. , Seifalian Alexander
Published: May 2022

In 2019, the whole world came together to confront a life-threatening virus named SARS-CoV-2,
causing COVID-19 illness. The virus infected the human host by attaching to the ACE2 and CD147 receptors
in some human cells, resulting in cytokine storm and death. The new variants of the virus that caused concern
are Alpha, Beta, Gamma, Delta, and Epsilon, according to the WHO label. However, Pango lineages designated
them as B.1.1.7, B.1.351, P.1, B.1.617.2, and B.1.429. Variants may be progressively formed in one chronic
COVID-19 patient and transmitted to others. They show some differences in cellular and molecular mechanisms.
Mutations in the receptor-binding domain (RBD) and N-terminal domain (NTD) lead to alterations in
the host's physiological responses. They show significantly higher transmissibility rates and viral load while
evading neutralizing antibodies at different rates. These effects are through mutations, deletion, and conformational
alterations in the virus, resulting in the enhanced affinity of RBD to PD of ACE2 protein, virus entry, and
spike conformational change. In the clinical laboratory, new variants may diagnose from other variants using
specific primers for RBD or NTD. There are some controversial findings regarding the efficacy of the developed
vaccines against the new variants. This research aimed to discuss the cellular and molecular mechanisms
beyond COVID-19 pathogenesis, focusing on the new variants. We glanced at why the mutations and the ability
to transmit the virus increase and how likely the available vaccines will be effective against these variants.
WITHDRAWN: Optimization Relation Between Antimicrobial Activities and Extraction of Clove Flowers Using Artificial Neural Network Model
Authors: Ahmed Essam Mohamed , Alsanie Walaa F. , Alhomrani Majid , Alayed Mohammed S. , Al-Hagrassi Ali
Published: May 2022

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn from the journal Current Pharmaceutical Biotechnology.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php.

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submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
Green Polymer Nanocomposites in Automotive and Packaging Industries
Authors: Susan Md. Abu Bin Hasan , Harun-Ur-Rashid Mohammad , Imran Abu Bin
Published: May 2022

Green polymer nanocomposites referred to as completely biodegradable, renewable, environmentally
friendly, and benign materials, have received a surge of attention to promote sustainable
development. Polymer nanocomposites, where nanomaterials are used for reinforcement, possess a
large interfacial area per volume, and the intervals between the filler nanoparticles and polymer matrix
are significantly short. Molecular interactions between the filler particles and the matrix, therefore,
provide polymer nanocomposites with novel characteristics that ordinary polymers or conventional
macrocomposites do not possess. However, nanoparticles, nanotubes, nanofilms, nanofibers,
nanoflakes, etc., in the form of nanocomposites may cause serious health hazards and pollute the
environment severely. While the number of review articles on fundamental and applied research
work of polymer nanocomposites is noteworthy, this review focuses more in depth on the applications
of safe and green polymer nanocomposites in the automotive and packaging industries. The
particular focus has been to examine and investigate in detail the initial and contemporaneous trends,
status, and perspectives of green and safe polymer nanocomposites in the automotive and packaging
industries. Background characteristics, strengths, weaknesses, potentiality, prospects, and opportunities
of green polymer nanocomposites suitable for automotive and packaging industries have been
addressed. The ultimate goal is to have a profound understanding of the structure-property relationship
of green polymer nanocomposites to overcome existing limitations for automotive and packaging
applications.
A Multi-dimensional Review on Severe Acute Respiratory Syndrome
Coronavirus-2
Authors: Ghosh Ketan , Chattopadyay Bumba , Maity Tapas , Acharya Ayan
Published: May 2022

The advent and spread of novel coronavirus (nCoV) has posed a new public health crisis
since December 2019. Several cases of unexplained pneumonia occurred in Wuhan, Hubei
Province, China, only a month before the Chinese Spring festival. After the diagnosis of bronchoalveolar
fluid samples of people infected, the new coronavirus was identified using nextgeneration
sequence technology. This work aims to provide information regarding COVID-19
that will help the researchers to identify the vital therapeutic targets for SARS-CoV-2 and also
will provide insights into some significant findings of recent times highlighted by scientific communities
around the globe. In this review, we have tried to explore multiple aspects related to
COVID-19, including epidemiology, etiology, COVID-19 variants, vaccine candidates, potential
therapeutic targets, the role of natural products, and computational studies in drug design and development,
repurposing, and analysis of crystal structures available for COVID-19 related protein
structures. Druggable targets include all viral enzymes and proteins involved in viral replication
and regulation of host cellular machines. The medical community tracks several therapies to combat
the infection by investigating various antiviral and immunomodulatory mechanisms. While
some vaccines are approved in this worldwide health crisis, a more precise therapy or drug is formally
recommended to be used against SARS-CoV-2 infection. Natural products other than synthetic
drugs have been tested by in silico analysis against COVID-19. However, important issues
still need to be addressed regarding in vivo bioavailability and better efficacy.
Water Purification by Green Synthesized Nanomaterials
Authors: Singh N.B. , Anindita De  , Guin Mridula , Barthwal Sumit
Published: May 2022

Background:

Water pollution is one of the leading causes for human fatality in the world particularly in underdeveloped or in developing countries. Moreover, with rapid industrialization and urbanization of rural lands, the problem of water pollution is posing a severe threat to communal health and livelihood these days. The pollutants found in water are of varied nature and depends on the source of the water. Several techniques have been so far adapted to purify contaminated water which includes both sophisticated, costly methods and simple and cost-effective methods. All these techniques have one or more disadvantages which limit their application in large scale, sustainable and long-term usage. The advances in the field of nanoscience and technology have opened a new horizon for replacement/ improvement of these conventional ways with more efficient methods. Presently green synthesized nanomaterials are being used for water purification.

Methods:

Plant extracts and microbes are being used to synthesize nanomaterials which are being used as catalysts, adsorbents and membranes for water purification.

Results:

Nanomaterial-based techniques could create problems on the environment due to various chemicals used in their production step and thus defeating the ultimate purpose. In this regard, green nanomaterials can prove to be extremely useful both in terms of sustainability and efficiency.

Conclusions:

This review illustrates various ways how green nanomaterials can be utilized for water remediation and summarize the recent work done in this emerging research front.
Epilepsy and Alzheimer’s Disease: Current Concepts and Treatment
Perspective on Two Closely Related Pathologies
Authors: Citraro Rita , Leo Antonio , Tallarico Martina , Sciaccaluga Miriam , Costa Cinzia
Published: May 2022

The literature on epileptic seizures in Alzheimer's disease has significantly increased over
the past decades. Remarkably, several studies suggest a bi-directional link between these two common
neurological diseases, with either condition carrying a nearly 2-fold risk of contracting the other
in comparison to healthy subjects. In this respect, evidence from both clinical and preclinical
studies indicates that epileptogenesis and neurodegeneration possibly share common underlying
mechanisms. However, the precise association between epileptogenesis and neurodegeneration still
needs to be fully elucidated. Targeted intervention to reduce abnormal network hyperexcitability
might constitute a therapeutic strategy to postpone the onset of later neurodegenerative changes and
consequent cognitive decline by many years in patients. By virtue of this, an early diagnosis and
treatment of seizures in patients with Alzheimer’s disease should be pursued. To date, no guidelines
are available for treating epileptic activity in this context, largely due to the paucity of studies sufficient
to answer the related questions. Accordingly, clinical trials are mandatory, not only to inform
clinicians about symptomatic management of seizures in Alzheimer’s disease patients but also to detect
if treatment with antiseizure medications could have disease-modifying effects. Moreover, it
will be fundamental to expand the application of animal models of Alzheimer’s disease to comorbid
conditions, such as epilepsy both to reveal the mechanisms underlying seizure onset and to better
define their role in cognitive decline. Such models could also be useful to identify pharmacological
compounds having therapeutically effectiveness as well as reliable early biomarkers for seizures in
Alzheimer’s disease.
Comparison of the Quality of Life and Post-traumatic Stress in Postmenopausal
and Non-menopausal Women after Hysterectomy in Selected Hospitals
of Shiraz University of Medical Sciences in 2020
Authors: Radmehr Zohreh , zarshenas Mahnaz , keshavarz Maryam , Akbarzadeh Marzieh
Published: May 2022

Background:

Hysterectomy is one of the most common gynecological surgeries that affect
women's mental health and quality of life.

Objective:

This study aimed to investigate the correlation between the quality of life and posttraumatic
stress in hysterectomized postmenopausal and non-menopausal women.

Materials and Methods:

This cross-sectional analytical study was conducted from August to December
2019 on hysterectomies postmenopausal and non-menopausal women. There were 77 subjects
in each group with a mean age of 52.55 ± 1.098. They were selected via convenience sampling
at Hazrat Zeinab (PBUH) and Shahid Dr. Faghihi Hospitals in Shiraz. They were evaluated in a
two-month follow-up using the Impact of Event Scale-Revised (Weiss & Marmar, 1997) and WHO
Quality of Life-BREF (WHOQOL-BREF) questionnaires. Data were analyzed in SPSS-16 software
using descriptive and inferential statistics (independent t-test, paired t-test, and Pearson or Spearman
correlation coefficients).

Results:

Unlike the first stage of the study (before and a week after the surgery, P = 0.289), there
was a significant negative relationship in the quality of life and post-traumatic stress between postmenopausal
and non-menopausal women (P = 0.001) in the second stage (two months after the surgery).
Hysterectomy increased the mean score of post-traumatic stress in postmenopausal and nonmenopausal
women after the surgery (P = 0.179), while the quality of life improved and stress decreased
two months later (P = 0.0001).

Conclusion:

Hysterectomy improved the quality of life in postmenopausal and significantly in nonmenopausal
women. Hence, due to the correlation and significant negative relationship between
post-traumatic stress and quality of life, midwives, families, and society need to pay attention to
women’s quality of life.
Molecular Study of Adenovirus Genotypes 40 and 41 in Children with
Acute Gastroenteritis
Authors: Essa Sara G. , Zaki Maysaa El Sayed , Elmansoury Eman A. , Hassan Rasha H. , EL Kheir Nermin Y.A.
Published: May 2022

Background:

Adenovirus is a common virus associated with acute gastroenteritis in children.
There are certain genotypes that are prevalent in these infections, such as genotypes 40 and 41.

Objective:

The aim of the present study was to investigate the incidence of adenovirus genotypes 40
and 41 in children with acute gastroenteritis by polymerase chain reaction (PCR) and also to determine
the possibility of Adenovirus co-infections with Rotavirus.

Methods:

The study was a cross-sectional study that included 100 children with acute gastroenteritis.
The children were subjected to full history taking and clinical examination. Stool samples from the
patients were subjected to detection of adenovirus and rotavirus antigens by enzyme-linked immunosorbent
assay (ELISA) and detection of adenovirus genotypes 40 and 41 by polymerase chain reaction
(PCR).

Results:

The most prevalent virus by the used methods was rotavirus antigen in the stool (35%). Adenovirus
antigen detection was positive in 23% of the stool samples, with positive PCR for these samples
in 22%. The ADv40 was detected in 13 samples, and ADv41 was detected in 9 samples. One positive
sample by adenovirus antigen ELISA was negative by PCR for these genotypes. Mixed rotavirus
and adenovirus by ELISA were detected in 7% of the children.
In patients with positive adenovirus antigen by ELISA, the most common symptoms were vomiting
(54.5%) and abdominal pain (45.5%). An insignificant difference between fever (P=0.94) and abdominal
pain (P=0.63) was detected in children infected with adenovirus compared to patients infected
with other organisms. The adenovirus was detected in 68.2% of children with acute gastroenteritis ≤ 24
months. Vomiting was significantly increased in children with adenovirus (54.5%) compared to children
negative for adenovirus (23.1%-P=0.004, OR 4.0, 95%CI: 1.5-10.8)

Conclusion:

The study highlights the presence of adenovirus genotypes 40 and 41 in the stool of children
with acute gastroenteritis. Combined rotavirus and adenovirus infections were detected in our study.
WITHDRAWN: A Comprehensive Pharmacological Review of Some Medicinally
Significant Plants of Bangladesh with Traditional Antipsychotic
Activity
Authors: Rafe Md. Rajdoula , Rahman Mahbubur , Sutra Dhar Ananta , Kabir Imonul , Biswas Subir
Published: May 2022

The article has been withdrawn from the journal Current Traditional Medicine.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.
WITHDRAWN: Physicochemical Properties and Biological Activities of Thyme (Thymus vulgaris L.) Seed and Leaf Oil Extracts
Authors: Turi Gebine , Yusuf Zekeria , Desta Mulugeta , Mengist Sewnet
Published: May 2022

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn from the journal "Current Traditional Medicine".

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

BENTHAM SCIENCE DISCLAIMER:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.