bluuebunny/crossref_metadata_2025 huggingface dataset:
PREVALENCE, PATTERN, AND PREDICTORS OF PREMENSTRUAL SYNDROME AND PREMENSTRUAL DYSPHORIC DISORDER AMONG COLLEGE GIRLS
Authors: K V LISHA GOVIND , V K CHELLAMMA
Published: February 2023

Objective: Premenstrual syndrome (PMS) occurs 7–14 days before the onset of menstruation and subsides with the commencement of menstrual flow, affects women during their reproductive age, and is associated with physical, psychological, and behavioral changes. If the mental symptoms predominate are very severe and are associated with impairment, then the patient is classified as having premenstrual dysphoric disorder (PMDD) which may be viewed as a severe subtype of PMS. This can interfere with the lives of the affected, as well as their interpersonal relationships.
Methods: This study was conducted at KMCT medical college from November 2021 to May 2022. An awareness program which was informative and well-interacted was conducted for each batch of students regarding the various aspects of this disorder before screening for this study. Premenstrual symptoms screening tool (PSST) was used to screen students for the presence of disturbing symptoms. They were asked to write down the various ways that they deal with these menacing symptoms in a separate form. Institution ethics committee approval was taken to carry out this study. PSST it is the screening tool developed by Steiner et al.
Results: A total of 318 students from all batches of college took part in this study actively. On screening by PSST, 44 students qualified for PMDD, 89 students met the criteria for PMS, and the remaining 185 had no to mild premenstrual symptoms (Table 1). Among the 89 students in premenstrual symptoms group, most common symptoms reported were anger/irritability −66%, fatigue/lack of energy −45%, and difficulty concentrating −45%. In 44 students who had qualified for PMDD, 84% reported anger/irritability, 81% reported tearful/increased sensitivity, and 75% reported anxiety/ tension followed by depressed mood in 73%.
Conclusion: PMS and PMDD are prevalent among substantial proportion of college girls with significant negative influence on academic performance, emotional well–being, and behavior. The pattern of premenstrual symptomatology is different between PMS, PMDD, and in overall college students. The predictors of PMS and PMDD are age, education, heavy menstrual flow, dysmenorrhea, and family history of PMS. The knowledge and health seeking behavior of college students toward PMD are quite low. Strategies should be drawn and implemented for timely recognition and management of PMS and PMDD in college girls.
PRESCRIBING PATTERN OF ANTIEPILEPTIC DRUGS IN PEDIATRIC PATIENTS AT A TERTIARY CARE TEACHING HOSPITAL
Authors: KAUSHAL PANCHAL , H SHAH MEGHA , CHETNA K DESAI
Published: February 2023

Objectives: Epilepsy is one of the common neurological conditions worldwide.
Methods: The observational, continuous, prospective, and single-center study was carried out to evaluate prescribing pattern of antiepileptic drugs (AEDs) in pediatric patients at a tertiary care teaching hospital of Gujarat for a total duration of 18 months. Patients were followed up monthly for the period of 3 months to evaluate seizure freedom, breakthrough seizure, and change in the AEDs, add-on therapy, treatment adherence and ADRs. Rationality was assessed for selection of drug and selection of the right dose according to recent guidelines.
Results: Majority of patients in the age group of 7–9 years with mean age of 6.83 ± 3.09 years. Male-to-female ratio was 1.3:1. Total 73 AEDs were prescribed to pediatric epilepsy patients after diagnosis. Thirty-seven (69.80%) patients were prescribed AED on visit as monotherapy and 16 (30.20%) patients were prescribed polytherapy. Sodium valproate (77.36%) was most commonly prescribed AED followed by levetiracetam and carbamazepine. Most of AEDs were prescribed according to NICE guideline and by generic name.
Conclusion: Conventional AEDs are still used as first line of treatment for pediatric epilepsy patients, although newer AEDs also frequently prescribed as add on or primary drug. Low birth weight, NICU admission, and non-compliance to treatment are associated with breakthrough seizures.
FORMULATION AND IN VITRO CHARACTERIZATION OF THE SOLID LIPID NANOPARTICLES OF NAFTOPIDIL FOR ENHANCING ORAL BIOAVAILABILITY
Authors: GUPTA BHARTI , SHARMA RAHUL
Published: February 2023

Objective: Naftopidil (NAF) is a selective alpha1-adrenergic receptor antagonist with a nearly 20% bioavailability due to poor aqueous solubility, permeability, and extensive first-pass metabolism. To improve the bioavailability of the NAF, the solid lipid nanoparticles (SLN) of NAF were prepared.
Methods: SLNs NAF were prepared using the solvent emulsification/evaporation method with excipients Compritol 888 ATO and Poloxamer 188. Formulation F10 shows better entrapment efficiency (EE) as compare to other formulations so, it has selected to optimize the particle size, zeta potential, surface morphology, Fourier transform infrared spectroscopy (FTIR), and in vitro drug release and stability studies were assessed.
Results: The results showed that NAF was successfully incorporated in SLN. Having EE of all formulations ranged from 56% to 88%, drug loading ranged from 17% to 20%, drug content ranged from 77% to 98%, particle size and zeta potential of F10 were 270.2 nm and 21.7 mV, respectively, and FTIR revealed no interaction between drug and lipid in the formulation. The release of NAF-SLNs increased significantly, reaching a maximum of 4.547–82.418% in pH 6.8 buffer, the release data were fitted into the Korsmeyer-Peppas model yielding the highest correlation coefficient (R2=0.916). The stability study revealed that the formulation stability and bioavailability might be improved.
Conclusion: It can be concluded that SLN could be effective nanoplatforms for increasing NAF oral bioavailability.
Ethics education plan for ‘confirmation bias’ using
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Yang Eunchang
Published: February 2023

Objectives This paper is a plan to understand the ‘confirmation bias’ thinking prevalent in our society and implement ethical education by using Lee Mun-yeol's short story . Through this, it has the purpose of upholding the right ethics and cultivating the transmitted thoughts.
Methods In this text analysis, I would like to apply J. Lacan's ‘desire theory’. Lacan's theory that human unconsciousness and consciousness form a dialectic like a Möbius strip centered on the imaginary and symbolic worlds is a representative theory that traces the fictions of the human mental world through the egocentric thoughts and desires inherent in the human mind. to be.
Results It is possible to know what principle ‘confirmation bias’ can be substituted into human unconsciousness and consciousness, and how it is related to human ethics. Therefore, you can learn a sound critical mind and ethics.
Conclusions Through this study, we understand the false principle of ‘confirmation bias’ and understand the human mental structure. In addition, it is judged that there will be an educational effect in terms of understanding the objective structure of ethical consciousness and self-identity that human beings must have, and understanding the conditions of healthy thinking.
A case study of a class of applying Tandem in Liberal education
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Cho Yunkyoung
Published: February 2023

Objectives In this research, we developed a collaboration course between foreign students and Korean students in the liberal arts courses for foreigners, and this is a case report that we conducted this for one semester.
Methods This study introduces tandem class as a case of a class for improving intercultural communicative competence. Tandem class is a class that applies tandem language learning in which a group of two people of different mother tongues gets together to learn each other’s language. In tandem class, foeign student and Korean student have one on one, face-to-face session to directly experience the target language and culture therefore it is the most proper teaching/learning method to improve intercultural communication competence. This study examines the trend of intercultural communication competence of 6 foreign students and 6 Korean students who took tandem classes 1 semester: how tandem classes were managed: and much the student improved and were satisfied.
Results In this research As a result of satisfaction, over 90% of students are satisfied of this tandem program. Therefore, tandem curriculum is developed and operated by the nationality or language area.
Conclusions It will increase the satisfaction of college life of foreign students and reduce the halfway dropouts, as well as provide a global mindset for Korean students.
Exploring the Digital Capacity Change and Growth Process of J Kindergarten Teachers in Pilot Operation of Future Curriculum
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Hyunjoo , Kim Younhee
Published: February 2023

Objectives This study attempted to explore the process of digital competency change and growth of J kindergarten teachers in operation of a pilot kindergarten for the future curriculum selected by the Ministry of Education.
Methods For the study, in-depth interviews were conducted twice for nine J kindergarten teachers in Incheon Metropolitan City who are participating in the operation of the future curriculum. Data analysis was conducted by summarizing and coding, adjusting subcategories and categories, nomadicization and hierarchization, and deriving upper categories according to research problems, followed by expert review and insider verification.
Results First, in the early days of the operation of the future curriculum, teachers recognized that digital media use education was a necessary curriculum to prepare for the future society according to the trends and demands of the times. Second, teachers experienced trial and error through the operation of the future curriculum to support infant play and learning, and children used digital media to approach, think, and expand the depth and breadth of learning. Third, teachers overcame the digital competency gap through communication and solidarity with fellow teachers. Low-experienced teachers familiar with digital media communicated in terms of technology use, and high-experienced teachers collaborated in a horizontal structure in terms of play application and support, and experienced changes and growth in digital capabilities in this process.
Conclusions J kindergarten teachers improved their digital capabilities through the operation of the future curriculum and tried to continue to challenge them as competent future teachers with digital capabilities.
Qualitative metasynthesis of nursing students' virtual reality simulation education experience
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Jiyoung
Published: February 2023

Objectives To help nursing students' in-depth understanding of VR simulation by reviewing, analyzing, synthesizing, and reinterpreting previous studies.
Methods In this study, the qualitative metasynthesis research method of Thomas and Harden was applied, and the paper was evaluated using CASP. Domestic and foreign papers were collected based on PRISMA from 2018 to October 11, 2022.
Results In this study, the results of qualitative metasynthesis were 5 topics and 13 subtopics. 1) The ambivalence of VR: the sense of feeling and seeing reality of virtual experiences, and the boredom with unreality 2) A convenient and safe world: VR is a safe zone for practicing and free from the constraints of space and time 3) Becoming a nurse: become an autonomous nurse, confidence in performance 4) Learning due to systemic thinking: steppingstone for learning, learning effect of a structured system, enjoyment of learning in VR, systematization of nursing process 5) Rethinking virtual reality: Lack of diversity in nurse cases, limited interaction, and difficulties in disordered virtual reality.
Conclusions As a result of this study, VR simulation has been verified as an effective educational method. In the future, the results of this study can be used as a basic material for the development and application of VR simulation programs.
Types of Longitudinal Changes in Youth Career Maturity and A Study on the Influential Factors of Social Activity
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, SHIN Jurang
Published: February 2023

Objectives This study categorized the trajectories of career maturity of adolescents according to the passage of time in consideration of the developmental stages of teen, and verified the predictive factors affecting each type.
Methods For this purpose, data from the 4th year among the 2013 panel data of the Korean Educational Longitudinal Study of the Korea Educational Development Institute were used. As an analysis method, latent class growth analysis was excuted to classify a career maturity change trajectory of a teenager and significant predictive factor was proved through multiple logistic regression analysis.
Results First, the career maturity level of the students was classified into three groups, and according to the change trajectory, the three groups were classified into a low-level increase group (1.8%), an average group (95.1%), and a high-level decrease group (3.1%). Second, the social activities that affect the group classification by level were care for others, cooperative behavior, and volunteer activitie, and the higher the care for others, the higher the probability of belonging to the high-level decrease group. Cooperative behavior and volunteer activities were likely to belong to the low-level increase group and average group.
Conclusions This study categorized the career maturity of adolescents into groups and examined the effects of social activity on the grouping. It shows that intervention at the school level is necessary for the variables of other-care, cooperative learning, and volunteer activities that affect the potential group classification in order to improve career maturity.
Analysis of Research Trends on Retention Integration: Focusing on papers from 2013 to July 2022
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Sun-Ai , Kang Hye-kyeong
Published: February 2023

Objectives The purpose of this study is to analyze research trends related to integration of kindergartens and day care centers from 2013 to July 2022, and to seek the overall direction of consolidation of kindergartens and pre-kindergartens.
Methods The data to be analyzed in this study were searched for the keyword ‘integration of kindergartens and day care centers in domestic academic portal sites such as the National Assembly Library, RISS, DBPIA, and KISS, and published annually, focusing on 80 theses and theses related to integration of kindergartens and pre-kindergartens in academic journals. The current status, research type, research subject, academic field, and research topic were analyzed. The frequency and percentage were calculated using the Excel program for the collected data, and reliability analysis inter coders was used to analyze the subject of the same paper to increase the validity and reliability of the study.
Results Looking at the results of the study, first, as for the publication status by year related to integration of kindergartens and day care centers, researches were most actively conducted in 2015 and 2017, and journal thesis papers were generally more conducted than theses. Second, in the case of research type, theory/documentary research and survey research were most actively conducted, while mixed research combining quantitative and qualitative research was found to be very insignificant. Third, as a result of examining the subjects of the study, most of the studies were conducted on childcare teachers on recognition of integration of kindergartens and pre-kindergartens and other studies on domestic integration policies and cases of integration of kindergartens and day care centersr abroad, as well as parents and daycare center directors, were conducted. Studies that investigated integrated cognition were identified. Fourth, most of the papers related to the integration of kindergartens and day care centers were made in education, and it was identified that some of them were also conducted in sociology. Fifth, as for the research topic, relatively active studies have been conducted to review the recognition of integration of kindergartens and day care centers, criticize/discuss domestic integration policies with integration of kindergartens and day care centers, consider cases of consolidation with kindergartens and pre kindergartens abroad, and suggest the development direction of domestic consolidations policies.
Conclusions In conclusion, domestic research trends related to integration with kindergartens and day care centers tend to focus on criticism and discussion of recognition of integration and policies for integration and studies that consider cases of consolidation abroad. This suggests that specific discussions and tendencies should be presented.
A study on pre-service teachers’ perceive of the descriptive evaluation of Home Economics subjects
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Baek Min Kyung , Park Chan-heung
Published: February 2023

Objectives The purpose of this study is to find out how Home Economics pre-service teachers perceive descriptive evaluation and to explore what and how to do in order to properly implement descriptive evaluation education for Home Economics subjects.
Methods A survey was conducted on the perception of descriptive evaluation among 51 students who were completing the preparatory tutoring course at J Teachers College in Jeonbuk region. And some of them were sampled and post-interview was conducted.
Results The survey results and interview results were summarized according to a total of 5 sub-factors, and the differences in perception between freshman-sophomore and senior graders, subjective descriptive evaluation and professionalism perceived by senior graders were derived.
Conclusions The main results of this study are as follows. First, sufficient education on basic knowledge related to descriptive evaluation should be further emphasized. Second, it is necessary to provide sufficient experience in conducting practical descriptive evaluation. Third, it is necessary to find a way to increase the descriptive evaluation efficacy. Fourth, educational contents related to the ethical issues of narrative evaluation should be provided.
Psychiatric Nurses' Attitude Toward the Mentally ill Effect of Professional Self-Concept and Self-Control on Patient-Centered Nursing: Focusing on the mediating effect of the grit
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Shim Eunhee , Yang Seunghee
Published: February 2023

Objectives This study is a descriptive research study to understand the impact on patient-centered nursing in psychiatric nurses.
Methods Data was collected at ten mental health hospitals in Seoul and Gyeonggi Province in January, 2022. A total of 190 questionnaires were distributed and 184 were returned and used in the final analysis. Collected data was analyzed in descriptive statistics, t-test, ANOVA, Scheffé-test, and Pearson’s correlation. Statistical significance was tested through bootstrapping.
Results The study analyzed the differences in patient-centered care according to the general characteristics of the subjects and found significant differences according to age, career, educational background, and position. A three-step model examined the effects of the independent variables and the mediating variable, grit, on patient-centered care as the dependent variable, and it had an explanatory power of 27.6% (adj R2=.260, F=17.041, p<.001). Professional self-concept (B=.251, p<.001) and grit (B=.201, p<.05) had significant positive (+) effects on patient-centered care.
Conclusions Professional self-concept had direct positive impacts on it and also indirect positive impacts via grit, which had partial mediating effects. Self-control had indirect positive effects on it via grit, which had full mediating effects.
Development of the Muslim Community of Tatarstan in 2022
Authors: Khabutdinov A. Y.
Published: February 2023

The article is dedicated to the evolution of the Muslim community in the Republic of Tatarstan (RT) in 2022. This publication continues a series of articles examining the Muslim community of Tatarstan in the 2000s and early 2020s. The article concludes that stability in the religious field is generally maintained in the Republic of Tatarstan. In the context of a Special Military Operation (SMO or SVO in Russian), as previously during the pandemic, social activism has become increasingly important. The most important socio-political issue for the Tatar religious figures of Russia was the preparation for and participation in the state-level celebration of 1,100 anniversary of adoption of Islam by the Bulgars. The law enforcement agencies in the republic continue to identify and punish representatives of extremist organizations banned in the Russian Federation.
Monitoring the Development of Islam in the Republic of Bashkortostan (by the Materials of 2021–2022)
Authors: Khabibullina Z. R.
Published: February 2023

The growing role of religion in interethnic relations, the importance of the Islamic factor in the socio-political sphere of society, the risks of religious radicalism necessitate annual monitoring of the development of the Islamic community in the Russian Federation. The article is devoted to the state of the Islamic community of the Republic of Bashkortostan in 2021–2022. The material used for analysis includes reports from state agencies, press reports, information on websites and pages of Islamic organizations, and materials from field work. Based on the data obtained, the main factors that influenced the development of Islam in the republic during the specified period were identified.
Jadidism as a New Type of Religiousity: Essay on Preliminary Conceptualization
Authors: Mukhetdinov D. V.
Published: February 2023

The present article focuses on understanding the phenomenon of Jadidism in the context of the global Islamic renewal movement. It consists of an introduction, two paragraphs and a conclusion. In the introduction, the author indicates the relevance and extent of discussion of the topic. It emphasizes the admissibility of various approaches to the thematization of this phenomenon. The first paragraph deals with some modern concepts in the historiography of the Jadid issue. It also criticizes an attempt to shut down this issue with a revisionist deconstruction of the opposition between Jadidism and Kadimism as presented in the works of D. DeWeese and some of his Russian supporters. The author argues for the absence of serious grounds for rejecting this opposition, for the rhetorical nature of its criticism and for the irrelevance of the revisionists’ arguments. In the second paragraph, the author shifts the focus from criticism of opponents to a “positive” presentation of some of the fundamental theses that must be taken into account when studying the Jadid movement. Based on the conceptual distinction between religiosity and religion, the author describes Jadidism as a new type of religiosity that has emerged as a result of responding to the challenges of modernity. At the same time, the term “modernity” itself is interpreted in the light of the theory of multiple versions of modernity. This helps to avoid an overly facile evaluation of Islamic modernism as an inherently Eurocentric phenomenon. Furthermore, the second paragraph points out that Islamic modernism, including Jadidism, is deeply rooted in the Islamic tradition of tajdid. The author concludes with his interpretation of the essence of the Jadid project.
Pengaruh Variasi Gliseril Monostearat pada Krim Ekstrak Kulit Buah Naga Merah Super (Hylocereus costaricensis) dan Uji Antioksidannya
Authors: Nugrahaeni Fitri , Yati Kori , Sukmara Sukmara
Published: February 2023

A Glyceryl monostearate can be used as an emulsifier because it can affect the increase in antioxidant activity. The study aims to determine the effect of fluctuations in the concentration of glyceryl monostearate (GMS) on the physical properties of cream preparations containing 70% ethanol extract from the skin of super red dragon fruit and their antioxidant activity. The research methods carried out experimentally include the manufacture of extracts from super red dragon fruit peel, phytochemical screening using thin layer chromatography, formulations using various concentrations of glyceryl monostearate 8%, 10%, 12% then the physical quality of the cream and antioxidant activity test using the DPPH method. The results of one-way ANOVA for pH, dispersion, adhesion, and viscosity tests showed a p-value of> 0.05, indicating that there was no significant difference. The IC50 results obtained with equations 1, 2, and 3 are 3.69 mg/L, respectively. 3.98mg/L; and 4.78mg/L. Formula 3 is the best formula and estimates the antioxidant activity of Vitamin C, which is a positive control, at a value of 5.83 mg/L. The results of the irritation test showed that none of the formulations caused irritation. The preference test results showed that the respondents liked all the formulas. The conclusion of this study is that increased fluctuations in the concentration of glyceryl monostearate did not affect the physical properties of super red dragon fruit skin extract cream, but did affect its antioxidant activity.
Validasi Metode Analisis Penetapan Kadar Protein Ekstrak Ikan Gabus dengan Metode Lowry dan Bromocresol Green
Authors: Suhendi Andi , Rohman Abdul , Cahyaningrum Safira
Published: February 2023

Snakehead fish is one of the biological resources with high economic value because it contains high albumin levels. Analytical methods for the determination of protein content in snakehead fish are available not been validated. This study aims to obtain a comparison of the accuracy, repeatability, intermediate precision, and linearity between the Lowry and Bromocresol-green methods in determining albumin levels from snakehead fish extracts. This study was performed with the SHIMADZU UV-1280 spectrophotometer at a wavelength of 778 nm for the lowry method and 638 nm for the bromocresol-green method. The results of the study show that all parameters meet the requirements for accepting validation. The results were tested statistically with the independent t-test, the p-value was 0.172 (p> 0.05) the accuracy between the Lowry and Bromocresol-green methods did not have a significant difference, that the Lowry and Bromocresol green methods had the same ability to determine accuracy parameters and precision parameters, the p-value is 0.000 (p
Pengaruh Pemberian Kombinasi Ekstrak Etanol Piper crocatum dan Ekstrak Akuades Elaeocarpus ganitrus pada Kadar Gula Tikus
Authors: Lestari Apriani , Kiromah Naelaz Zukruf Wakhidatul , Fitriyati Laeli
Published: February 2023

Diabetes mellitus is a disease characterized by hyperglycemia. Antidiabetic research using natural ingredients has been carried out a lot, one of which is by utilizing red betel leaves and granite leaves. Combining two plants must be done to increase the antihyperglycemic effect and reduce the toxic effects. This study aimed to obtain the most effective dose variations in combinations of plants that are safer and have better results so that they can be used as alternative treatments. The blood sugar levels were measured in vivo on white Wistar rats induced with streptozotocin using a glucometer. The results showed that a single extract of red betel leaf (100 mg/kg BW) and a single extract of granite leaf (100 mg/kg BW) had a percentage decrease in blood sugar levels of 27% and 10%, respectively. While the combination of extracts with a ratio of 100:100, 50:50, 100:50, and 50:100 mg/kg BW has a decrease in blood sugar levels of 50%, 42%, 33%, and 19% after 21 days of observation. The study also showed that the positive control of 0.036 mg glimepiride caused a 36% decrease in sugar levels. Statistical analysis proved that the effect of reducing blood sugar levels on days 0 to 21 differed for each treatment group with a p-value of 0.05. The study concluded that the combination of red betel leaf extract and granite leaf extract was more effective on blood sugar levels than the single extract of each plant in white male Wistar rats. The percentage reduction in blood sugar levels of the combination extract with a dose ratio of 50:50 mg/kg BW and 100:100 mg/kg resulted in better antidiabetic activity than the positive control glimepiride. The combination ratio of 100:100 mg/kg BW extract had the best antidiabetic activity compared to the other extract treatment groups.
Local Fractional Kamal Transform Decomposition Method to Solve for Nonlinear Local Fractional Partial Differential Equations
Authors: ANAÇ Halil
Published: February 2023

In this work, the local fractional Kamal transform decomposition method
is used to solve a nonlinear system of local fractional partial
differential equations. The local fractional Kamal decomposition
transform method combines the Adomian decomposition method and a local
fractional Kamal transform. There are some applications of the nonlinear
system of local fractional partial differential equations.
Prevalence and Phylogenetic Analysis of Rhinoviruses in Patients with Acute Respiratory Infections and Community-Acquired Pneumonia in a referral hospital, Tehran, Iran
Authors: Fazl Shadi , hassani somayeh , Nia Mahboobe Ramezan , Nadji Proshat Sadat , Nemati Fahimeh , marjani majid , Nadji Seyed Alireza
Published: February 2023

Introduction. Rhinoviruses are known as the leading pathogens of
respiratory diseases. Determining the prevalence and phylogeny of
rhinoviruses plays a pivotal role in producing vaccines and medications
and preventing virus complications. This study investigated the
frequency, and genetic variation of rhinoviruses detected in patients
referred to Masih Daneshvari Hospital. Materials and Methods. It was a
descriptive cross-sectional study. The samples were from all ages whose
information was recorded in 2017 according to a clinical diagnosis of
acute respiratory infection (ARI) and in 2015 based on a clinical
diagnosis of community-acquired pneumonia (CAP) within the HIS system of
Masih Daneshvari Hospital. Using a random number table, 202 patients
diagnosed with ARI and 51 patients diagnosed with CAP were selected. The
real-time PCR method was used for primary screening; nested PCR was
performed in VP2/VP4 gene region for phylogenetic investigations, and
MEGA software drew a phylogenetic tree. Results. The highest level of
rhinovirus infection was seen in subjects under 18 years of age, males,
and during the spring season. In this study, the genotypes of HRV-A
(including A15, A29, A40, A47, A58, A67, and A80) and HRV-C (including
C39 and C44) and two samples of enterovirus D68 were found. Discussion
and Conclusion. Like other studies conducted in Asia, the most detected
genotypes were HRV-A and HRV-C. Conducting further studies with a larger
sample size and in different geographical regions of Iran will provide
us with more comprehensive information about the frequency of
rhinoviruses and common genotypes.
50 Years of Research on Dopamine’s Role in Passive Aversive Conditioning and Extinction: A Systematic Review
Authors: Hamati Rami , Ahrens Jessica , Shvetz Cecelia , Holahan Matthew , Tuominen Lauri
Published: February 2023

Dopamine, a catecholamine neurotransmitter, has historically been
associated with the encoding of reward, whereas its role in aversion has
received less attention. Here, we systematically gather the vast
evidence for a role of dopamine in the simplest form of aversive
learning: passive aversive conditioning and extinction. In the past,
crude methods were used to augment or inhibit dopamine in order to study
its relationship with fear conditioning and extinction. More advanced
techniques such as conditional genetic, chemogenic, and optogenetic
approaches now provide causal evidence for dopamine’s role in these
learning processes. Dopamine neurons encode fear and extinction-related
information and convey the signal via activation of D1, D2, D3, and D4
receptor sites particularly in the amygdala, prefrontal cortex, and
striatum in order to continuously form, consolidate, retrieve, and
update fear and extinction memory in a dynamic and reciprocal manner.
Based on the reviewed literature, we conclude that dopamine is crucial
for the encoding of passive aversive conditioning and contributes in a
way that is comparable to its role in encoding reward.
HOW TO INCREASE THE SURVIVAL RATE OF ENTREPRENEURS IN CRISIS TIME
Authors: Chaves-Maza Prof. Manuel , Fedriani Eugenio M.
Published: February 2023

There are variables linked to the type of support service demanded by
entrepreneurs, which, along with other characteristics of entrepreneurs
and their projects, may account for a significant part of the variations
in their survival rate. After applying structural equations modelling,
with some probability as a function of these variables, a prediction of
the survival rate could help to offer a better support service for
entrepreneurs. The data set is composed of 2,221 entrepreneurs and 83
variables and help us to achieve a model with global significance. The
variables that explain a more significant part of the variability of
survival are the number of employees and participation in local
development programs. This research may help improve one of the programs
with the most considerable dissemination worldwide. The budget assigned
to public organizations dedicated to implementing these services is
increasing in most of the developed countries, to ease the creation of
employment.
The Future of Auditing: An Interview with Robert Elliott
Authors: Elliott Robert , Duan Huijue Kelly
Published: February 2023

This paper examines the future of auditing based on responses received on November 22, 2021, from Robert Elliott, who is a retired partner at KPMG Peat Marwick LLP, former chairman of the AICPA Special Committee on Assurance Services, and past Chair of the Board of the AICPA. Robert provided his views on different perspectives of audit practices and changes. His responses in this study cover the value of auditing, the importance of information, the development of information technology, and the future changes in the audit profession.
Connecting From Afar: Implementation of Remote Data-Sharing for Patients With Type 1 Diabetes on Insulin Pump Therapy
Authors: Grimaldi Monica , Cardenas Lisania , Saenz Aleida Maria , Saalinger Maddison , Odugbesan Ori , Rioles Nicole , Ebekozien Osagie , Bernal-Mizrachi Ernesto , Vendrame Francesco
Published: February 2023

Quality Improvement Success Stories are published by the American Diabetes Association in collaboration with the American College of Physicians and the National Diabetes Education Program. This series is intended to highlight best practices and strategies from programs and clinics that have successfully improved the quality of care for people with diabetes or related conditions. Each article in the series is reviewed and follows a standard format developed by the editors of Clinical Diabetes. The following article describes an effort to improve the remote collection of insulin pump data in an academic center in South Florida.
Specific-class Skin Side-effects of Drugs Might Compromise Blinding in Randomized Controlled Trials
Authors: Do-Pham Giao , Maruani Annabel , Leducq Sophie , Giraudeau Bruno , Chosidow Olivier
Published: February 2023

Abstract is missing (Short communication)
Information system for extraction of information from open web resources
Authors:   Lviv Polytechnic National University, Zdebskyi Petro , Berko Andriy ,   Lviv Polytechnic National University, Chyrun Lyubomyr ,   Ivan Franko National University of Lviv
Published: February 2023

The purpose of the work is to develop a project of an information and reference system for finding answers to questions based on the highest degree of comparison using text content from open English- language web resources. Examples of such questions can be: “What is the best book ever?”, “What is the most popular IDE for Python”. The result of the functioning of the information and reference system is a ranked list of answers based on the frequency of appearance of each of the answer options. Also, a numerical characteristic of the probability of the preference of a particular answer over others is added to each element of the list. Based on this metric, the obtained results are ranked. This information and reference system works with questions to which there is no unequivocal answer, what differs it from classic information systems for finding answers to questions of the QA-system type. The latter have a hypothesis that there is only one true answer to the question, often such systems work with well-known facts. Examples of questions they answer can be, for example, the date of birth of a famous person, or the population of a certain country. Instead, the proposed information and reference system answers subjective questions, for example, “What is the best book in the fantasy genre?” or “What is the best programming language?”. The system is based on the popularity of one or another answer. Proper names based on the analysis of N-grams are also keywords for forming the answer to the question.
Information support system for household waste disposal processes
Authors:   Lviv Polytechnic National University, Borovets Nazar , Bublyk Myroslava ,   Lviv Polytechnic National University, Chyrun Lyubomyr ,   Ivan Franko National University of Lviv
Published: February 2023

In work, a web application was designed and developed to support interaction between members of different households regarding the disposal of household waste and the sale of used goods on the secondary market. To minimize the negative human impact on the environment, the developed information system to support household waste disposal is based on the principles of a circular economy, where all available resources are reusable, goods to recycle, and in general, the level of consumption is reduced. The need to form the average consumer’s interest in finding a target audience for the distribution process on the secondary market of used goods is substantiated. The main distinguishing feature of the web application is providing consumers with an electronic platform that would provide an opportunity to successfully realize the need for sorted garbage (household waste, recyclables, etc.) with economic benefits for all participants of the interaction. As a result of the task, we carried out an analysis of knowledge in the direction of household waste disposal and existing applications to support circular economy processes. According to the compiled requirements specification, we used the TypeScript programming language, the React library, the SASS scripting metalanguage, and the MVC architecture. To ensure the correct operation of the service, manual, modular and automated testing was carried out. The developed software product has a simple interface. It is easy to use for every user who has access to the Internet and a desire to obtain additional resources in the difficult time of Ukraine’s military economy.
Increasing selenium concentration in Finnish organic milk using participatory action approach
Authors: Kuusela Eeva , Okker Laura , Kopra Juho
Published: February 2023

Selenium (Se) is an essential trace element for animals. In Finland, Se supplementary feeding and Se-enriched macronutrient fertilisers are used in conventional farming because the Se availability from soil is extremely low. The objective of this study was to improve Se concentration in organic milk by replacing sodium selenite (SS) in mineral-vitamin mixture with selenium yeast (SY) either completely or partly (50/50). The feeding experiment was conducted on 15 certified organic dairy farms in Eastern Finland during spring 2008. The cross-over design consisted of three treatments (SS treatment, SY treatment, and SS/SY treatment), three experimental periods (28 days each), and three farm groups (different order of treatments). Replacing SS with the same amount (0.2 mg Se kg-1 feed dry matter) of SY more than doubled Se concentration in organic milk and their mixture resulted in slightly lower Se concentrations. In conclusion, SY supplementary feeding is needed to improve Se concentration in organic milk and Se supply to cows, their calves, and consumers.
Morphological and Molecular Characterization of Gnetum africanum (Welw.) Germplasm Using DNA Barcoding Method
Authors: Nya Elijah , Owoh Lucy , Udofia Ofonime , Udosen Inyang , Ogidi Eme G. , Elijah Godwin
Published: February 2023

Gnetum africanum is a twisted woody climbing wild plant i.e.liana found growing naturally in dense equatorial rainforest but currently domesticated in tropical areas of the world. There has been taxonomic confusion in classifying this liana due to its observable diverse morphological characters. Indeed, morphological characterization alone has not offered the needed solution. However, there is dearth of information on the molecular characterization of Gnetum africanum. Morphological and molecular descriptors, could help offers the needed phenotypic and genotypic characterization of this plant much better. This study is aimed at characterizing Gnetum africanum land races to identify species that could be used for the development of high yielding hybrids. Three different land races or accessions of Gnetum africanum was collected from different locations in Nigeria. High quality genomic DNA was isolated from the different samples; it was checked for purity and quantified as appropriate. The DNA samples were subjected to PCR amplification and DNA barcoding studies (chloroplast large subunit of ribulose -1, 5-bisphophate carboxylase rbcL gene). The amplicons were gel eluted, sequenced and checked for homology by using Basic local alignment search tool -BLAST. Identification was obtained from the top similar outcomes of the samples. For Ekim Fig. 1b sample, the forward blast showed 95% similarity with Basella alba voucherID: NC041293.1 and the reverse had 88% similarity with Talinum fruticosum cultivar ID: MK598685.1. For Etinan Fig. 1a sample, the forward blast had 86% similarity with Rhabdothamnussolandri voucher ID: JQ933464.1 and for reverse, there was no similarity founded.
Analysis of the Effect of Service Quality on Customer Loyalty Through Commitment Service Quality: Study in Rest Area 65A and 65B Jasa Marga Kualanamu Tol
Authors: Putranti Honorata Ratnawati Dwi , Hendaryadi Dedi , Widayati Tri
Published: February 2023

The purpose of this study is to examine the impact of service quality on customer loyalty using commitment to service quality as a mediating variable. The approach used in this study is a quantitative approach. This research using the sample from the tenant partners in Rest Area 65A and 65B Jasa Marga Kualanamu Toll. With the total of 190 respondents. The survey data were obtained from the results of completing a questionnaire and analyzed using the SEM-PLS analysis technique with the help of the SmartPLS program. The results show that service quality influences service quality commitment. Commitment to service quality affects service quality, but service quality does not directly affect customer loyalty. Quality of service can impact tenant retention when mediated through the involvement of tenant sales engagement in quiet areas.
PENGARUH LAYANAN PENGUASAAN KONTEN TEKNIK MODELING TERHADAP RESILIENSI AKADEMIK SISWA DI SMPS AMIR HAMZAH MEDAN T.A 2021/2022
Authors: Maharani Mella , Menanti Asih
Published: February 2023

AbstractThis study aims to determine the effect of modeling technique content mastery services on the academic resilience of students at Amir Hamzah Medan Private Junior High School Period 2021/2022.  The method used in this study is a quantitative method.  This type of research is a quasi-experimental with a pre-test-post-test group design.  The subjects in this study were 22 grade VIII students who had low resilience.  The research data were collected with an academic resilience scale totaling 40 statement items that were valid and reliable.  Instruments are given before and after the implementation of content services.  The data were analyzed using the Wilcoxon test to see if there was a significant effect of providing modeling technique content mastery services on students’ academic resilience.  This can be obtained from the calculation results with the initial test score (pre-test) in the experimental group obtained an average = 109.4 while the post-test data obtained an average = 135.4.  This can be obtained from the Wilcoxon test which shows that the Wilcoxon level test is obtained Jcount = 115 while Jtable = 66. From the critical table J for the Wilcoxon marked level test for n = 22, = 0.05 according to the criteria for acceptance and rejection of the hypothesis, the hypothesis  accepted if Jcount > J table where 115 > 66, from this calculation it can be seen that the treatment in the experimental group means that the hypothesis is accepted.  This shows that there is an influence of modeling technique content mastery services on students’ academic resilience at Amir Hamzah Medan Private Junior High School. Period. 2021/2022.
Vnímání města v kontextu historické památky na příkladu chebských krovů
Authors: Tlučhoř Jan , Přibáň Pavel , Gangur Mikuláš , Ircingová Jarmila , Jakubíková Dagmar , Janeček Petr , Maříková Hana , Štumpf Petr
Published: February 2023

The paper deals with the perception and image of the town Cheb in the context of historical heritage. Since 2017, the town has been running a tour of historic trusses. The aim of the research was to determine the influence of this activity on the image of the town, or whether the historic roofs already form part of the image of the town at least for some Czech residents and citizens. So far, the image of the city has not been systematically investigated. Two surveys have been carried out, one among the city residents and one among the citizens of the Czech Republic. It was found that the city of Cheb is associated with historical heritage in the minds of the respondents. However, outside the town of Cheb the historical trusses are not yet sufficiently associated with the perception of it. The article also presents a semantic differential with citizens' perception of the town of Cheb.
Una elegía desextractivista
Authors: Ríos Carlos
Published: February 2023

Chtonic Futur y CO2 Show son dos proyectos que Carlos Ginzburg diseñó para su exhibición en 2022 en la Sala A y en el Pasaje del Bicentenario del Centro de Arte de la UNLP. Carlos Ríos recorre ambas intervenciones y a la manera de una elegía advierte sobre un arte urgente y proteico, que señala nada más -ni nada menos- lo que se ve.
METODE SOROGAN DALAM MENINGKATKAN MINAT DAN KETERAMPILAN MEMBACA KITAB KUNING SANTRI Al-AFIYAH BOGOR JAWA BARAT
Authors: Arifin Adiyatna , . Fakhruddin , Hajja Ristianti Dinna
Published: February 2023

The most common problem for students is the difficulty in understanding the yellow book they read. Therefore, how to increase interest and reading skills in students increasingly attract attention, especially for students of Al Afiyah Citeureup by using sorogan method. The author has analyzed some general reading skills and put forward some suggestions for further increase in interest for students, especially students al afiyah from personal experience as well as the experience of the general public who have studied pesantren from several interviews of ustadz, which can help improve the competence of reading students themselves with the practice of using sorogan methods.