bluuebunny/crossref_metadata_2025 huggingface dataset:
Attitudes and Knowledge of Infertile Iranian Couples Among Treatment with Assisted Reproductive Technologies During COVID-19 Pandemics
Authors: Peivandi Sepideh , Razavi Alireza , Shafiei Shervin , Zamaniyan Marzieh , Orafaie Asma , Jafarpour Hamed
Published: May 2022

Objective: The coronavirus disease 2019 (COVID-19) pandemic affected the continuation of all non-emergency medical treatment and patients potentially suffer from restrictions including patients under infertility treatment. This study aimed to evaluate the knowledge and attitudes of infertile couples about continuing assisted reproductive technologies (ARTs) therapy during the COVID-19 outbreak, in Sari, Iran.
Materials and methods: We conducted a prospective longitudinal investigation on potential infertile couples for treatment with ARTs referred to our infertility clinic from March 2020 to June 2020. Ninety-two patients were studied voluntarily and anonymously in this study. A self-developed structured questionnaire was used to assess the attitude towards continuing infertility treatment. A P-value of less than 0.05 was considered statistically significant.
Results: Thirty-two patients (33.33%) had decreased motivation to continue treatment during the COVID-19 pandemic. Fear of transmission to the fetus (28.13%) had the highest frequency among the causes of decreased motivation to continue treatment (P-value = 0.011). Trust on the support of the treatment team (56.67%) was the most common reason for not reducing motivation in patients without decreased motivation (P <0.001).
Conclusion: Despite the COVID-19 pandemy, in Iran most infertile patients tended to continue ARTs. Although many patients had passable knowledge on COVID-19, the stress of infertility and the high desire of infertile couples to have children did not deter them from continuing their therapy.
Investigating the Molecular miRNAs as Biomarkers of Type 2 Diabetes
Authors: Sadeghzadeh Salman , Dehghani Ashkezari Mahmood , Seifati Seyed Morteza , Vahidi Mehrjardi Mohammad Yahya , Sadeghzadeh Sara
Published: May 2022

Introduction: Biomarkers would significantly improve the early detection of the disease and identification of individuals at risk of emerging complications. Diabetes mellitus is a group of diverse and complex metabolic disorders. Both type 1 diabetes (T1D) and type 2 diabetes (T2D) mellitus are associated with distinct alterations in the profile of MicroRNAs (miRNAs) in the blood, which are sometimes detectable several years before the disease manifests. Lately, considerable attention has been paid to the role of miRNAs as biomarkers for T2D. The aim of this study was to review the expression of different miRNAs in pre-diabetic (per-T2D), T2D and healthy groups.
Conclusion After evaluating several articles, including main articles, meta-analysis and review studies, it was found that the expression of micRNAs was statistically different in healthy, pre-T2D and T2D groups. In addition, the expression of specific miRNAs is useful in preventing disease and modifying gene structure.
This study indicated that the plasma expression level of miRNAs could be considered as a non-invasive and fast tool for the separation of pre-T2D individuals from their healthy counterparts.
Synthesis and Evaluation of Gold Nanoparticles/Nanorods to Use in Plasmonic Photothermal Therapy
Authors: Darvishi Elahe , Amani Asra , Mirsadeghi Somayeh , Shiri Varnamkhasti Behrang
Published: May 2022

Introduction: Photothermal therapy is a method of cancer treatment that plasmonic nanoparticles are used to convert infrared light into local heat. Due to the plasmonic properties of gold nanoparticles, this compound was used as a contrast agent. The aim of this study was to synthesize gold nanoparticles with different conjugations for photothermal therapy.
Methods: This research was an experimental study. The method used for the synthesis of spherical and rod gold nanoparticles in this research was the Seeding Method. The nanoparticles were then conjugated with various compounds such as rifampicin, quercetin and RGD. Then, the physical and chemical properties of nanoparticles were determined by DLS, UV-Vis and TEM methods. Cytotoxicity test was also performed on MCF-7 ((Michigan Cancer Foundation-7)) cell line. Cell viability was calculated using prism software. Differences were compared by analysis of variance (ANOVA) using SPSS version 16 software.
Results: In the UV test, two-peaked rod nanoparticles were observed in the range of 523 and 738 nm, and in the case of spherical nanoparticles at 535 wavelengths, which indicates the correct synthesis without impurities and with the appropriate size .In the cell test, a decrease in cell viability was observed compared to the control group. In the first 24 hours, spherical nanoparticles had the highest lethality to the point that at a concentration of 20 μg / ml, it had almost 50% lethality. In addition, after 48 hours at low concentrations, rod nanoparticles showed better results, so they were more suitable. By targeting these nanoparticles to specific cancer cells, in addition to being used to kill cancer cells, the effect of these nanoparticles on healthy cells can be prevented. By conjugating different compounds on the surface of these nanoparticles, cell uptake can also be increased and cancer cells can be killed using photothermal therapy.
Conclusion: According to the results obtained in this study, it seems that low-concentration of gold nano-rods are more suitable for photothermal therapy.
Evaluation the Protective Role of Gallic Acid on Cardiac Arrhythmias Induced by Oxidative Stress in Rat Exposure to Particulate Matters
Authors: Dianat Mahin , Radan Maryam , Badavi Mohammad , Mard Ali , Bayati Vahid , Goudarzi Gholamreza
Published: May 2022

Introduction: Particulate matter (PM) increases the risk of heart disorders. Gallic acid (GA) with strong antioxidant properties has shown an effective role in reducing the complications of various diseases. The aim of this study was to evaluate the protective effect of Gallic acid in preventing cardiac arrhythmias due to exposure to particulate matter.
Methods: In this study, 40 rats were placed in 4 groups including: control, Particulate matter (5 mg/kg), Gallic acid (30 mg/kg) and particulate matter + Gallic acid. The rats were anesthetized, blood pressure was measured with a tail cuff, and the lead Π of electrocardiogram was examined to record the prevalence of cardiac arrhythmias. Oxidative stress factors were evaluated in blood samples of all groups. Data were analyzed by SPSS software version 16 and ANOVA statistical test.
Results: The results showed the occurrence of cardiac arrhythmia in rats exposed to particulate matter compared to the control group. Gallic acid significantly reduced the incidence of ventricular arrhythmias ventricular tachycardia (P=0.006), ventricular fibrillation (P=0.0005) and premature ventricular contraction (P=0.0041) in the particulate matter group. The Malondialdehyde levels in the particulate matter group showed a significant increase (P=0.0049) that this increase caused oxidative stress and reduced the levels of superoxide dismutase (P=0.00031) and catalase (P=0.0019) in the particulate matter group compared to the control group. The Gallic acid administration improved the levels of antioxidant enzymes.
Conclusion: The results of this study show that Gallic acid as a natural antioxidant agent could prevent cardiac complications caused by exposure to particulate matter.
Małe miasta nowo utworzone w procesie urbanizacji
Authors: Konecka-Szydłowska Barbara
Published: May 2022

Celem opracowania jest ukazanie znaczenia nowo utworzonych małych miast w procesie urbanizacji Polski i poszczególnych jej województw. W rozdziale przedstawiono rozkład przestrzenny nowych miast i ich typ historyczno-genetyczny. Poziom urbanizacji mierzony jest za pomocą trzech mierników: (a) liczbą miast, (b) odsetkiem ludności miejskiej, (c) gęstością sieci miast, rozpatrywanych głównie w układzie regionalnym. Uzupełnieniem opracowania są wstępne wyniki badań ankietowych przeprowadzone w pięciu nowych miastach: Bobowej, Brzostku, Krynkach, Michałowie i Szczucinie (powstały w 2009 r.).
Przemiany strefy centralnej (rynków) małych miast Polski Środkowej
Authors: Kowara Sylwia
Published: May 2022

Przedmiotem prowadzonych badań są rynki w wybranych małych miastach województwa łódzkiego (jego centralnej i zachodniej części), takich jak: Uniejów, Poddębice, Stryków, Błaszki, Warta, Szadek, Wieruszów, Zelów, Rzgów i Tuszyn. Wymienione miasta nie przekraczają liczby 10 tys. mieszkańców i pełnią funkcję ośrodków lokalnych z siedzibą gminy miejsko-wiejskiej, w przypadku Poddębic i Wieruszowa ich ranga wzrasta do roli stolicy powiatu. Granice rynku wyznaczać będzie płyta rynku oraz działki do niej przylegające, wchodzące w skład bloków przyrynkowych.
Biocontrol Capacity of the Soil Fungus Trichoderma harzianum against Fusarim oxysporum f. sp. albedinis, a Causal Agent of Fusarium Wilt (Bayoud) Disease of Date Palm (Phoenix dactylifera L.)
Authors: Belaidi H. , Toumi-Benali F. , Benzohra I.E. , Megateli M. , Boumaaza B. , Megherbi A. , Bouzidi M.A.
Published: May 2022

Backgraound: This study has the objective to study antifungal effect of the antagonistic fungus of soil named Trichoderma harzianum on mycelial growth of twenty isolates of Fusarium oxysporum f. sp. albedinis (Foa), agent of the bayoud disease on the date palm, originated from south western region of Algeria. Methods: Twenty Foa isolates obtained from isolation of the spines carrying the typical symptoms of Bayoud disease were used. The strain of T. harzianum was isolated from rhizosphere soils of the date palm trees. The in vitro test affected by two tests of confrontation, direct which is dual confrontation and indirect confrontation by volatiles substances, on mycelial growth. Result: A statistical analysis showed a significant difference (P less than 0.05), of Foa isolates reaction against the antagonistic fungus T. harzianumin the test realized.The results of in vitro test showed a significant effect (P less than 0.05), on mycelial growth in both tests used. The inhibition rate (IR) of mycelial growth of Foa by T. harzianum varies between 28.42 and 59.12%, with 12 Foa isolates showed IR, more than 50% in the direct test and between 3.3 and 56% with just three (3) isolates have IR more than 50% in the indirect test by volatile substances. Based on these encorageous results, we can apply of this antagonistic fungus to protect our groves contaminated by Bayoud disease and also contain this susceptible commercial variety.
İntihar Sonrası Yas Süreci: Bir Sistematik Gözden Geçirme
Authors: DAĞ Büşra Nur , YALÇINKAYA ALKAR Özden
Published: May 2022

İntihar alanyazında sıkça çalışılan bir konu olagelmişken, ölümle sonuçlanan intihar sonrasında geride kalanların nasıl bir yas süreci yaşadıkları göz ardı edilen konulardan biri olmuştur. Sistematik derlemenin amaçları arasında; bu konuda alanyazına katkı sağlamak ve intihar sonrası yas süreci yaşayan kişilerin yas süreçlerinin nasıl şekillendiğini anlayabilmek bulunmaktadır. Ek olarak yasa yönelik hayata geçirilebilecek müdahale programlarında dikkat edilmesi gereken önemli noktalara değinilmiştir. Bu doğrultuda, sistematik derleme çalışmasına intihar eden kişinin geride kalan yakınlarının risk grubunda olup olmadığını anlayabilmek için karşılaştırılmalı grupların bulunduğu nicel çalışmalar ve yaşanılan yas sürecini derinlemesine anlayabilmek için yapılan nitel çalışmaların birlikte dahil edilmesine karar verilmiştir. Scopus, PubMed, ScienceDirect, EBOSCO ve ProQuest veritabanları taranmış ve sistematik derlemeye 28 çalışma dahil edilmiştir. Derlemenin akış diagramı ve çalışmaların özeti tablolarla birlikte sunulmuştur. Bulgulara göre, intihar sonrası yas süreci yaşayan kişilerin yas sürecinin farklı bir biçimde şekillendiği dile getirilebilir. İntihar sonrası yas süreci yaşayan kişilerin yas sürecine dair dikkat edilmesi gereken noktalar ve buna yönelik öneriler çalışmanın tartışma ve sonuç bölümünde verilmiştir.
Bilinçsiz Önyargı: Tanımı ve Önemi
Authors: SUVEREN Yaşar
Published: May 2022

Bu çalışma, ‘bilinçsiz önyargı’ kavramına ilişkin psikoloji, sosyal psikoloji ve kısmen sosyolojideki literatüre bağlı olarak bilinçsiz önyargı olgusu ve kavramı hakkında güncel gelişme ve tartışmaları ele almayı amaçlamaktadır. Bilinçsiz önyargı, kavramın adının da açıkça işaret ettiği üzere insanların önemli bir kısmının farkında olmadığı olumsuz bir kavram ve olgudur. Bu yanıyla da insanlar arası ilişkiler ve toplumsal yaşamdaki ilişkilere olumsuz etkileri bulunmaktadır. Bu nedenle bu çalışma bilinçsiz önyargı hakkında farkındalık oluşturmaya ve insanların daha nesnel görüşlere sahip olabilmelerine katkıda bulunmayı da amaçlanmaktadır. Bilinçsiz önyargı, karar vermede yaşanan sistematik hata olarak tanımlanmaktadır. Çoğu durumda, kişi mevcut bilgileri anlamlandırmaya çalışırken önyargılı hale gelebilir. İnsanların bazılarının önyargılarından habersiz olduğu söylenebilir. Günümüzün karmaşık dünyasında, insanlar aynı anda işleyemeyeceği birçok bilgiye maruz kalmaktadır. Bu nedenle, karar verirken doğal olarak zihinsel kısa yollara başvurmaya eğilimlidir. Bilinçsiz veya örtük önyargı, farklı teorik yaklaşımlar etrafında açıklanmıştır. Sistem 1 ve 2, beynin nasıl yavaş ve hızlı kararlar aldığını gösterir. İkili tutum modeli ise, insanların aynı konuda hem örtük hem de açık tutumlarını nasıl geliştirdiklerini göstermektedir. Son olarak, sosyal kimlik teorisi, bireylerin olumlu özellikleri kendi iç gruplarıyla nasıl ilişkilendirdiğini ve olumsuz kalıp yargılarını da dış gruplarla nasıl ilişkilendirdiğini göstermektedir. Bilinçsiz önyargılar, toplumsal yaşamın farklı alanlarında kendisini dışavurabilmektedir. Kavram hakkındaki araştırma ve tartışmalar, olumsuz çağrışımların ve klişelerin okullarda, işyerlerinde, sağlık hizmetlerinde, siyasette ve hukuk alanında nasıl ve ne biçimlerde ayrımcılığa işaret ettiğini göstermektedir.
Improving Exclusive Breastfeeding Behavior of Primipara Mothers With Lactation Education and Individualized Counseling Intervention
Authors: Aylyyewa Gulsoltan , Topatan Serap
Published: May 2022

Introduction

New mothers often need support to establish and maintain breastfeeding, and they may find it difficult to access breastfeeding resources locally. Therefore, postpartum lactation education and counseling of primipara mothers were given by integrating into their routine follow-ups in the family health center. This study was conducted to determine the effect of lactation education and individual counseling intervention integrated into the routine follow-up visits of primipara mothers in family health centers on exclusive breastfeeding rates and breastfeeding behaviors during the first 6 months postpartum.

Methods

A two-factor, pretest–posttest, controlled, semi-experimental, prospective study was conducted. The study was conducted in three family health centers in a city on the north coast of Turkey. The interviews with the primipara mothers were performed between the 24th and 72nd hours and at the 1st, 3rd, 4th, 6th months postpartum.

Results

The rates of giving exclusive breastfeeding to the infants in the first 6 months were 68% in the study group and 38% in the control group, exhibiting a statistically significant difference between the groups with regard to breastfeeding frequency (p =.001).

Conclusions

It was determined that the education and counseling integrated into the existing health system were effective in increasing the EBF rates and breastfeeding behaviors of primipara mothers in the first 6 months after birth.
Growing the interprofessional workforce for integrated people-centred care through developing place-based learning cultures across the system
Authors:   Kent and Medway CCG, Chatham, England, Germaine Ruth , Manley Kim ,   University of East Anglia, Norwich, Stillman Kim ,   HEE KSS, Kent, England, Nicholls Peter J ,   University of Kent, Canterbury, Kent, England
Published: May 2022

Background: The World Health Organization’s global strategy presents compelling evidence for the need to develop people-centred and integrated health services. However, there is a dearth of literature on learning at the macro-systems level focused on ‘place’ that is required to meet these ambitions. Aims: This article positions place-based learning at the heart of integrated care to contribute understanding of learning for transformation to inform continuous improvement and workforce development. Second, using practice development methodology, it demonstrates how to develop a shared understanding for place-based learning, sustained through a co-created implementation and impact framework. Methods: Five facilitated co-creation workshops with key stakeholders drew on participants’ collective knowledge, expertise and values to develop a shared understanding and direction. Collaborative themes arising from the workshops were used to populate a concept analysis framework for place-based learning, to identify its attributes, enablers and impacts. Findings: A shared purpose for and definition of place-based learning resulted, with three interdependent value themes: people-centred learning; cultures of teamwork to enable learning; and networks for learning together. Enablers, attributes and other factors were identified to support successful implementation and evaluation across one region in England. Conclusion: Place-based learning is a new concept previously undefined in the context of health education and integrated healthcare systems. The insights that emerged increase our understanding about how this concept can support local, national and global strategies, optimising the contribution of learning to integrated health and social care. Implications for practice: Integrated health and social care services need to: Grow a critical mass of skilled facilitators with the capabilities to integrate learning and improvement with other functions (such as embedded research) so as to develop systemwide   Enable leaders to create learning cultures collectively with facilitators to increase understanding about the impact of culture on learning and improvement Develop indicators of the impact of learning across place
Relationships, roles and person-centred practices – collaborative birthing care in Nova Scotia
Authors:   Queen’s University, Ontario, Canada, Macdonald Danielle
Published: May 2022

Background: Collaboration is an important factor in creating and maintaining safe and effective spaces in perinatal healthcare. Family-centred care has been used by perinatal nurses to provide care that focuses on the family. Woman-centred care is defining for midwifery, and centres care around women’s expert knowledge and decision making. Person-centred care extends these approaches to include all persons involved in healthcare. The ongoing integration of midwives into existing perinatal healthcare teams in Canada has created new opportunities for collaboration. Understanding how midwives and nurses collaborate can offer insights into how collaboration is influenced by different approaches. Aim: The aim of this study was to understand how midwives and nurses collaborate in Nova Scotia, Canada. Methods: Feminist poststructuralism guided this case study. The data collected included 17 individual participant interviews, document review and field notes. Feminist poststructuralist discourse analysis was used to analyse the data. Results: The two main themes discussed in this article were negotiating roles and practices, and sustaining relationships. In the first theme, participants talked about how they negotiated their roles, how their skills and practices crossed over and the importance of communication and anticipation. In the second theme, participants described how they test trust, the ways in which midwives depend on nurses, and a need for more opportunities to work, learn and socialise together. Conclusion: The relationships between midwives and nurses in Nova Scotia support their collaboration and contributions to ensuring their workplaces are safe and effective. The participants described intuitive engagement with person-centredness. Implications for practice: The Person-centred Practice Framework should be used to facilitate collaboration in perinatal healthcare Individual, institutional and systemic commitments to intentional engagement with practice development are needed to support healthful cultures in perinatal healthcare Research is needed to explore how family-centred and woman-centred care approaches may support person-centred practices and cultures
Key Considerations: Engaging 'People on the Move' to Promote COVID-19 Vaccine Acceptance in Italy
Authors: Torre Costanza
Published: May 2022

This key considerations brief outlines perceptions, understandings and experiences of COVID-19 vaccination among ‘people on the move’ in Italy. For an increasing number of such people, Italy is considered a transit destination to reach other European countries. Considerations in this brief are relevant to countries situated along Eastern and Central Mediterranean migrant routes. EU policymakers have expressed concern about the vulnerability of mobile populations – a group which includes refugees, asylum seekers and undocumented migrants – in relation to COVID-19. Due to the extreme mobility of these populations, coupled with a fear of state authorities, public health experts have linked communities to a heightened risk of COVID-19 transmission within and across national borders. Yet, the same factors which link mobile populations to transmission of COVID-19 also make these individuals hard to reach through state-led vaccination campaigns. This brief highlights the complexities of this humanitarian situation and provides advice as to vaccination approaches which take account of people’s specific vulnerabilities and priorities. This brief draws on research conducted along Italy’s Alpine border in 2021. This brief was developed for SSHAP by Costanza Torre (LSE) with support from Elizabeth Storer (LSE) and Sara Vallerani (Roma Tre University). Additionally, contributions and reviews were provided by Megan Schmidt-Sane (IDS), Eloisa Franchi (Université Paris Saclay – Pavia University), and Professor Federico Federici (UCL). This brief is the responsibility of SSHAP. The research was funded through the British Academy COVID-19 Recovery: G7 Fund (COVG7210058). Research was based at the Firoz Lalji Institute for Africa, London School of Economics. The brief is the responsibility of SSHAP.
Strategi Pembelajaran Analogi dan Kemampuan Pemahaman Konsep Matematika
Authors: Rendrayana Ketut , Suarsana I Made , Parwati Ni Nyoman
Published: May 2022

This study aimed to determine the effect of analogy learning strategies on the ability to mathematical conceptual understanding.  This research is a quasi-experimental study using pretest-posttest control group design.  The research population was class VIII of SMP Negeri 2 Sawan in the academic year 2019/2020, which was then sampled using cluster random sampling techniques to obtain students in class VIIIA and VIIIC as an experimental group and students in class VIIIB and VIIID as a control group.  The ability to understand students' mathematical concepts was tested using essays tests both pre-test and post-test.  After the data is collected, it is then analyzed using the one-way ANACOVA test with a significance level of 5%.  Based on the results of research conducted, obtained FA * = 17,369 ≥ F table = 3,918.  These results indicate that the student sability to understand mathematical concepts who are taught by using analogy learning strategies are better than conventional learning.  Therefore analogy learning strategies have a positive influence on the ability to understand mathematical concepts.
Mnemic Images in the Early Works of Sigmund Freud
Authors: Błocian Ilona
Published: May 2022

Freud was interested in the problem of memory from the time of his very early works. The processes taking place in memory, imaging, remembering and forgetting images focused his attention and were one of the pillars of shaping his conception of the unconscious and mind as “the storehouse of total memory,” which in one of his works he compared to “the Eternal City of Rome” (Culture and Its Discontents), which accumulate images-memories gathered throughout life. Shifts, changes, deformations, strong emotional components determine the specificity of many processes of remembering and forgetting, a specific “coding” of information in the form of visual, acoustic and other images. Nowadays, there are indications of Freud’s views in various dimensions of scientific research on memory and the consciousness of the importance of these approaches in our culture and its discovery of the role of autobiographical memory.
Ser Professor e os sentidos da Didática por meio da lição tríplice: renascimento, conhecimento, compaixão
Authors: Fortunato Ivan , Araújo Osmar Hélio , Medeiros Emerson Augusto de
Published: May 2022

Neste texto, tomados pela inquietação a respeito do futuro do magistério como campo de formação e atuação profissional, escarafunchamos os possíveis sentidos da Didática imbuídos na última frase do livro “O terceiro instruído”, de Michel Serres: “Re-nascido, ele conhece, ele tem compaixão. Agora sim, ele pode ensinar”. Examinamos cada fragmento da frase, em busca de significados mais profundos para o exercício duplo de ser professor e de ser professor formador de novos professores. Em essência, trata-se de renascer, conhecer e sensibilizar(-se) cotidianamente.
Carbon footprints of the Indian AFOLU (Agriculture, Forestry, and Other Land Use) sector: a review
Authors: Kumar B. Mohan , Aravindakshan Sreejith
Published: May 2022

Stabilizing greenhouse gas (GHG) emissions from croplands as agricultural demand grows is a critical climate change mitigation strategy. Depending on management, the Agriculture, Forestry, and Other Land Use (AFOLU) sector can be both a source as well as a net sink for carbon. Currently, it contributes 25% of the global anthropogenic carbon emissions. Although India’s emissions from this sector are around 8% of the total national GHG emissions, it can contribute significantly to the country’s aspirations of reaching net-zero emissions by 2070. In this review, we explain the carbon footprints of the AFOLU sector in India, focusing on enteric fermentation, fertilizer and manure management, rice paddies, burning of crop residues, forest fires, shifting cultivation, and food wastage. Furthermore, using the standard autoregressive integrated moving average method, we project India’s AFOLU sector emission routes for 2070 under four scenarios: business as usual (BAU) and three emission reduction levels, viz., 10%, 20%, and 40% below BAU. The article focuses on how the AFOLU sector can be leveraged proactively to reach the net-zero emission goals. Increasing forest cover, agroforestry, and other tree-based land-use systems; improving soil health through soil management, better crop residue, and livestock feed management; emission avoidance from rice ecosystems; and reducing food waste are all important strategies for lowering India’s AFOLU sector carbon footprints.
THE IMPACT OF LONG HAUL, LOW COST FLIGHTS: LINKING THAILAND TO JAPAN AND SOUTH KOREA
Authors: C.H. Law Colin
Published: May 2022

Purpose - Since the success of low-cost airlines in Thailand in 2014, the low-cost airline industry has expanded the market for long-haul flights. The objective of this study is to determine the impact of long-haul low-cost carriers (LHLCs) on tourism demand and aircraft movements between Thailand and two East Asian countries. Design/Methodology - The study includes the total number of air travellers (AIR) as the dependent variable and the explanatory variables are the total number of full service carrier (FSC) aircraft movements, long-haul low cost airline (LHLC) aircraft movements, inbound travellers from Japan and South Korea (ITOR), and outbound travellers from Thailand to Japan and South Korea (OTOR). Approach - To examine the long-run relationship between the variables, this study employed the pooled mean group autoregressive distributed lag model using 96 monthly data between 2012 to 2019 (8 years) of air traffic and tourism data between Thailand and Japan, and Thailand and South Korea. Findings - The results of the study conclude that LHLC airlines have been motivating demand for travel between Thailand, Japan and South Korea. LHLC airlines have attracted travellers from Japan and South Korea to Thailand and also serviced Thai travellers travelling to Japan and South Korea. The LHLC airlines have given travellers more options to choose from. The reduced airfares have made travel more affordable, which has motivated travel intentions. However, questions relating to the sustainability of the LHLC airlines’ operations remain as the services have lower cost efficiency and rate of aircraft utilisation compared to the short haul business. Originality of the research - LHLC airlines are relatively new operations in the Asia-Pacific market. This study contributes to the knowledge of these airlines in the aviation industry by identifying whether they increase tourism demand in a country.
CHALLENGES AND UNCERTAINTIES IN RIO’S HOSPITALITY INDUSTRY: THE CASE OF ASTOR HOTELS
Authors: Russo Eduardo , Figueira Ariane
Published: May 2022

International mega sporting events such as the Olympic Games have been responsible for promoting transformations over the years in the cities they pass through whether through developing economic sectors such as tourism, hospitality, and services or through transforming their urban spaces. The case of Rio de Janeiro in 2016 was emblematic above all for the city’s hotel sector, which during the years preparing for the Games saw its offer in the number of beds increase by 76% in a period of just 5 years, which generated a new competitiveness dynamic for the region. The case puts the reader in the role of Federico Gonzales, manager of Astor Mediterranean Rio, a new hotel that opened near the Olympic Park at the end of 2015 and is currently experiencing serious financial difficulties given the drop in demand aggravated by the economic crisis and by the effects of the pandemic. The case is indicated for undergraduate and graduate students from the hospitality, tourism, and strategy courses interested in discussing themes and concepts related to the area of strategic transformation of hotel industry, management strategic decision making, and mega events.
Pemberdayaan Masyarakat Berbasis Pariwisata pada Destinasi Wisata Stone Garden dan Gua Pawon
Authors: Maryani Neni , Paramita Veronika Santi , Prabowo Juddy , Adialita Tania
Published: May 2022

Pada era new normal, Kelompok Sadar Wisata (Pokdarwis) Pasir Pawon menghadapi kendala untuk membangkitkan kembali destinasi wisata Stone Garden dan Gua Pawon yang mati suri terdampak pandemi Covid-19. Stone Garden merupakan destinasi wisata alam geopark di puncak bukit yang menyajikan hamparan bebatuan aneka bentuk dan ukuran yang artistik dan eksotis dengan panorama alam sangat indah. Sedangkan Gua Pawon kaya akan stalaktit dan memiliki jejak kehidupan manusia purba. Kedua destinasi wisata yang berada di wilayah Bandung Barat ini dapat menawarkan wisata alam, sejarah, budaya, edukasi dan petualangan yang potensial berkembang di kemudian hari dengan pengelolaan profesional. Program bertujuan menggerakkan perekonomian masyarakat dengan mengoptimalkan peran Pokdarwis. Program dilaksanakan melalui beberapa sub program yang terdiri dari: 1) Program Penguatan Kelembagaan Pokdarwis: Pelatihan Manajemen dan Pencatatan Keuangan, Pelatihan Pemandu Wisata; 2) Program Pemasaran Berbasis Digital: Pelatihan Digital Marketing; 3) Program Kewirausahaan: Pelatihan Motivasi berwirausaha (Kuliner, Cenderamata dan Pertunjukan Seni Budaya), Pelatihan Manajemen Homestay.
Pengenalan Teknologi Multimedia Melalui Pelatihan Pembuatan Gim Edukasi Storytelling
Authors: Mahardhika Galang Prihadi , Huda Sheila Nurul , Rani Septia
Published: May 2022

Teknologi multimedia merupakan teknologi yang telah digunakan pada hampir seluruh sektor di era digital. Untuk menghasilkan artefak-artefak multimedia yang berkualitas, salah satunya diperlukan keahlian dalam bidang desain. MAN 4 Sleman memiliki kelas keterampilan Desain Komunikasi Visual (DKV) yang mengajarkan siswa untuk membuat berbagai desain digital, seperti desain stiker, mug, dan lain-lain. Hal ini sejalan dengan keilmuan kelompok klaster Multimedia dan Visi Komputer di Program Studi Informatika - Program Sarjana, Universitas Islam Indonesia. Keterkaitan ini mendorong klaster Multimedia dan Visi Komputer untuk turut mendukung kelas keterampilan DKV di MAN 4 Sleman dalam mengembangkan kreativitas melalui kegiatan pengabdian masyarakat. Kegiatan pengabdian kepada masyarakat ini dilakukan dalam bentuk pelatihan yang terdiri dari 3 tahapan, yaitu pengenalan teknologi multimedia, pengembangan aset multimedia, dan pemanfaatan aset multimedia. Hasil akhir dari pelatihan tersebut adalah sebuah aplikasi gim storytelling. Hasil evaluasi melalui testimoni peserta dan guru menunjukkan bahwa kegiatan pelatihan ini berjalan dengan menyenangkan dan memberikan pengalaman baru bagi siswa. Kreativitas kelompok dan individual diasah melalui sesi kelompok (penyusunan alur cerita) dan sesi individual (pengembangan aset multimedia).
Essential Terminology and Considerations for Validation of Non-targeted Methods
Authors: Nichani Kapil , Uhlig Steffen , Stoyke Manfred , Kemmlein Sabine , Ulberth Franz , Haase Ilka , Döring Maik , Walch Stephan G. , Gowik Petra
Published: May 2022

Through its suggestive name, non-targeted methods (NTMs) do not aim at a predefined "needle in the haystack". Instead, they exploit all the constituents of the haystack. This new form of analytical methods is increasingly finding applications in food and feed testing. However, the concepts, terms, and considerations related to this burgeoning field of analytical testing needs to be propagated for the benefit of ones associated in academic research, commercial development, and official control. This paper addresses the frequently asked questions around notations and terminologies surrounding NTMs. The widespread development and adoption of these methods also necessitates the need to develop approaches to NTM validation, i.e., evaluating the performance characteristics of a method to determine if it is fit-for-purpose. This work aims to provide a roadmap to approaching NTM validation. In doing so, the paper deliberates on the different considerations that influence the approach to validation and provides suggestions thereof.
Differences and Similarities in Breast and Colorectal Cancer Screening Uptake among Municipalities in Flanders, Belgium
Authors: Ferrari Allegra , Thuy Tran Ngan , Hoeck Sarah , Peeters Marc , Goossens Mathieu , Van Hal Guido
Published: May 2022

Despite the recognized benefits of fecal occult blood test (FOBT) and mammography screenings, participation in breast (BC) and colorectal cancer (CRC) screening programs is still suboptimal. This study investigates municipal characteristics associated with their BC/CRC screening uptake profiles among women aged 55–69 years. Using data from 308 municipalities of Flanders from 2014 to 2017, a profile for each municipality based on its BC/CRC screening uptake compared with the median screening uptake was created. Logistic regression with generalized estimating equations was used to assess the associations between municipal characteristics and BC/CRC screening uptake profiles. The overall median uptake of cancer screening was higher for CRC (57.4%) than for BC (54.6%). The following municipal characteristics were associated with worse performance in terms of only CRC, only BC, or both CRC and BC screening uptake, respectively: foreign nationality, self-employment rate, (early) retirement rate, diabetes, disabilities; (early) retirement rate; age group 65–69, foreign nationality, self-employment rate, (early) retirement rate, wage-earners, diabetes. The following municipal characteristics were associated with better performance in terms of only CRC, only BC, or both CRC and BC screening uptake respectively: residential stability, having a partner, having children, jobseeker rate, GP visits, preventive dental visits; having children, GP visits; age group 55–59, residential stability, having a partner, having children, jobseeker rate, higher education, GP visits, preventive dental visits. This study’s results regarding the interrelation between the BC and CRC screening could be used to tailor interventions to improve the participation of the target population in both programs.
A Critical Analysis of Using Roy's Adaptation Model in Nursing Research as an Empirical for Clinical Practice: a Systematic Review
Authors: Hasanah Idyatul , Nursalam Nursalam , Pandin Moses G. R. , Ikhwani Dina A. , Rohita Tita
Published: May 2022

Background: One way to demonstrate the existence of nursing is to develop a nursing theory model through nursing research which can ultimately be implemented in nursing practice. RAM is one of the most frequently used models in guiding nursing research. Roy's Adaptation Model (RAM) is one of the most useful conceptual frameworks that guide nursing practice, direct research, and influence education. Theory-guided nursing practice is fundamental in providing the framework for developing superior and quality nursing care.Objectives: This systematic review aims to critically analyze recent studies using RAM as a conceptual framework to identify the effectiveness of this model in guiding nursing research.Methods: A literature search was conducted on five databases, namely SCOPUS, PubMed, ProQuest, ScienceDirect, and SAGEPub. There were no population boundaries and diagnoses involved in the study. The study is a quantitative design focused on publication between 2015-2021. The methodological quality of applying the Cochrane and JBI bias tools. The analysis uses narrative synthesis.Results: 20 studies were found out of 1,315 studies. The research population found is very diverse. The given intervention follows the conceptual framework of RAM. RAM-based interventions effectively overcome the problems experienced by patients and reduce the perceived symptoms and improve the patient's quality of life.Conclusion: The conceptual use of RAM theory in nursing research has been widely reported. RAM-based interventions have a significant impact and have strong evidence-based practice in improving patient health status.
Interaction Between Melatonin and NO: Action Mechanisms, Main Targets and Putative Roles of the Emerging Molecule NOmela
Authors: Martinez-Lorente Sara E. , Pardo-Hernadez Miriam , Marti-Guillen Jose M. , López-Delacalle Maria , Rivero Rosa M.
Published: May 2022

Melatonin (MEL), a ubiquitous indolamine, is a molecule whose regulatory role in plan metabolism has gained interest in the last decades. Likewise, nitric oxide (NO), a gasotransmitter, can also affect plant molecular pathways due to its function as a signalling molecule. Both MEL and NO can interact at multiple levels under abiotic stress, starting by their own biosynthetic pathways and inducing a particular signalling response in plants. This review summarizes the role of these molecules during plant development and fruit ripening, as well as their interactions. Due to the impact of climate change‐related abiotic stresses on agriculture, this review has also focused on their role in mediating abiotic stress tolerance and the mechanisms by which they operate, from upregulation of the whole antioxidant defence system to posttranductional modifications of important molecules. Their interactions and crosstalk with phytohormones and H2S is also discussed. Finally, we introduce NOmela, an emerging and very unknown molecule which seems to have a stronger potential than MEL and NO separately in mediating plant stress response.
Design of Non-Tactical Deployable 20 Gwh (17.20841 Kilo Ton TNT) Fusion Device - Energy Basis
Authors: Rafique Muhammad Musaddique Ali
Published: May 2022

Fusion device and its structure may be designed by various means. Two of most popular are; weight basis (described in previous study by author) and energy basis. In present research, later method is explored and described. Energy basis is based on amount of energy released from device upon detonation followed by explosion. Its beneficial in a sense that device size can be kept as independent variable as compared to dependent in former case. Further, it shortens the design procedure. For example, heat transfer pattern in such approach directly helps in quantifying wall thickness which dictates material, fabrication, and manufacturing route. It may also eliminate anisotropy as wall thickness is direct function of amount of heat at which it will rupture and can be much thinner. Device geometry can also be flexibility controlled as it is no longer dependent on pay load bay capacity. This allows more freedom in designing subsystems (compartments, their locations, focusing, switches, and mixers). Such devices can be more compact and simpler. Few such design configurations are proposed.
Energy Recovery Potential from Effluents in the Process Industry: System Dynamics Modeling and Techno-Economic Assessments
Authors: Adepoju Tofunmi , Momodu Abiodun S. , Ogundari Ibikunle , Akarakiri Joshua
Published: May 2022

This study quantified effluents generated during processing in three industry types, estimated the energy potential from the quantified effluents in form of biogas generation, and determined the economic viability of the biogas recovered. Data were procured from relevant scientific publications to quantify the effluents generated from the production processes in the industry types examined using industrial process calculations. The effluent data generated was used on the 2-module biogas energy recovery model to estimate the bioenergy recovery potential within it. Economic and financial analysis was based on cash flow comparison of all costs and benefits resulting from its activities. The effluents generated average daily biogas of 2559 Nm3/gVS, having a daily potential combined heat and power of 0.52 GWh and 0.11 GWh respectively. The Life Cycle Analysis and cost-benefit analysis show the quantity of avoided emissions from using the effluents to generate heat and power for processes, and also the profitability of the approach. Conclusively, the study shows the use of biomass effluents to generate biogas for CHP is a viable one based on the technologies of a reciprocating engine, gas turbine, microturbine, and fuel cell. However, it is recommended that the theoretical estimation be validated using a field-scale project.
Reductions in Anxiety, Depression and Insomnia in Health Care Workers using a non-pharmaceutical intervention
Authors: B.S. Katherine Currie , Gupta Babu V , Shivanand Ishan , Desai Amit , Bhatt Shweta , Tunuguntla Hari S , Verma Sadhna
Published: May 2022

The COVID-19 pandemic has caused significant medical and psychological challenges worldwide, and not only exceeded the capacity of hospitals and intensive care units but also an individuals’ ability to cope with life. Health-care workers have continued to provide care for patients despite exhaustion, fear of transmission to themselves and their family, illness or death of friends and colleagues, and losing many patients. They have also faced additional stress and anxiety due to long shifts combined with unprecedented population restrictions, including personal isolation. In this study, we study the effect of an app-based Yoga of Immortals (YOI) intervention on mental health of healthcare workers. In this study, the health care workers were digitally recruited, and their psychological parameters were measured using validated questionaries. The participants were randomly grouped into control and test groups. The validated psychological measures were the Patient Health Questionnaire-8 (PHQ-8), Insomnia Severity Index (ISI) and generalized anxiety disorder (GAD-7) scales. The digital YOI intervention significantly reduced the anxiety, depression symptoms, and insomnia in healthcare workers of all age groups. In contrast, there was no improvement in the control group. This study details the effectiveness of an app-based YOI intervention in healthcare workers.
Planar Strained Layer Superlattice Infrared Photodetectors Fabricated by Ion-Implantation
Authors: Dehzangi Arash
Published: May 2022

Strained layer superlattice (SLS) material system is being considered for large format, small-pitch and low-cost focal plane arrays for different applications. To address difficulties associated to focal plane arrays fabrication arising from mesa-isolation etching or complex surface treatment/ passivation process, planar structures have been considered. In this work, the recent progress on planar SLS photodetector using ion-implantation for device isolation is presented. The devices are presented here are nBn and pBn heterostructure InAs/InAsSb SLS photodetector, where Zn and Si were chosen as the ion implants, respectively. The electrical and optical performance of the devices were compared along with comparison with mesa-etched device, to give deeper view of the device performance.
Reversal of CSF HIV-1 Escape During Treatment of HIV-Associated Cryptococcal Meningitis in Botswana
Authors: Kelentse Nametso , Moyo Sikhulile , Molebatsi Kesaobaka , Morerinyane Olorato , Bitsang Shatho , Bareng Ontlametse T. , Lechiile Kwana , Leeme Tshepo B. , Lawrence David S. , Kasvosve Ishmael , Musonda Rosemary , Mosepele Mosepele , Harrison Thomas S. , Jarvis Joseph N. , Gaseitsiwe Simani
Published: May 2022

Cerebrospinal fluid (CSF) viral escape has been poorly described among people with HIV-associated cryptococcal meningitis. We determined the prevalence of CSF viral escape and HIV-1 viral load (VL) trajectories in individuals treated for HIV-associated cryptococcal meningitis. A retrospective longitudinal study was performed using paired CSF and plasma collected prior to and during the antifungal treatment of 83 participants recruited at the Botswana site of the phase-3 AMBITION-cm trial (2018-2021). HIV-1 RNA levels were quantified then CSF viral escape (CSF HIV-1 RNA ≥ 0.5 log10 higher than plasma) and HIV-1 VL trajectories were assessed. CSF viral escape occurred in 20/62 (32.3%; 95% confidence interval [CI]: 21.9%-44.6%), 13/52 (25.0%; 95% CI: 15.2%-38.2%) and 1/33 (3.0%; 95% CI: 0.16%-15.3%) participants at days 1, 7 and 14 respectively. CSF viral escape was significantly lower on day 14 compared to days 1 and 7, p=0.003 and p=0.02, respectively. HIV-1 VL de-creased significantly from day 1 to day 14 post antifungal therapy in the CSF but not in the plasma (OR, 0.56; 95% CI: 0.41-0.77; p<0.001). CSF viral escape is high among individuals presenting with HIV-associated cryptococcal meningitis; however, antifungal therapy may reverse this, highlighting the importance of rapid initiation of antifungal therapy in these patients.