bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of Cryptosporidium parvum IIa and IId zoonotic subtype families and Cryptosporidium bovis from calves in Algeria
Authors: Sahraoui Lynda , Mammeri Mohamed , Thomas Myriam , Chevillot Aurélie , Polack Bruno , Vallée Isabelle , Follet Jérôme , Ain-Baaziz Hacina , Adjou Karim Tarik
Published: November 2023

Cryptosporidiosis is a significant disease in calves caused by the parasitic protist Cryptosporidium. The infection results in severe symptoms such as diarrhea, dehydration, delayed growth, and weight loss, often leading to mortality and economic losses. This study aimed to detect Cryptosporidium spp. in fecal samples from calves in five Algerian provinces. A total of 65 fecal samples from calves were collected from 12 dairy cattle farms in the north-east of Algeria. The presence of the parasites was established by microscopic screening of the oocysts following an immunofluorescence assay (IFA). IFA-positive samples were analyzed by 18S rRNA PCR-RFLP (restriction fragment length polymorphism) to determine the species. Cryptosporidium parvum was subtyped by sequence analysis of the 60 kDa glycoprotein gene. Cryptosporidium oocysts were detected microscopically in 41/65 (63%) samples, of which 26/41 (63.4%) were positive by 18S rRNA PCR-RFLP. Two Cryptosporidium species were detected in 24 samples; C. parvum (20/24) and C. bovis (4/24). C. parvum isolates from IIa and IId zoonotic subtype families were detected: IIaA16G2R1 (9/24), IIdA16G1 (4/24), and IIaA15G2R1 (1/24). Thus, calves are reservoirs of zoonotic C. parvum subtypes and represent a public health concern.
DETECTION AND PATHOGENICITY LEVEL SCREENING OF HEMOLYTIC BACTERIA ISOLATED FROM UNPACKED CHICKEN NUGGET
Authors:   Diploma of Health Analyst Study Program, Faculty of Nursing and Health Sciences, Universitas Muhammadiyah Semarang, Alfiyani Ika , Mukaromah Ana Hidayati ,   Magister of Clinical Laboratory Science, Postgraduate Program, Uiversitas Muhammadiyah Semarang, Afriansyah Muhammad Ardi ,   Diploma of Health Analyst Study Program, Faculty of Nursing and Health Sciences, Universitas Muhammadiyah Semarang, Ethica Stalis Norma ,   Magister of Clinical Laboratory Science, Postgraduate Program, Uiversitas Muhammadiyah Semarang
Published: November 2023

Food poisoning is a severe threat that can lead to death. According to the WHO, cases of food poisoning have been on the rise in recent years. Pathogenic bacteria are responsible for food poisoning, often originating from contaminated food. Chicken nuggets, a popular ready-to-eat food, are susceptible to bacterial growth due to the risk of microbial contamination during storage. This study aims to assess the pathogenicity levels of bacteria in chicken nuggets when stored at room temperature for seven days. Samples from chicken nuggets left at room temperature were diluted and cultured on Nutrient Agar (NA) media. Subsequently, bacterial pathogenicity screening was conducted using MacConkey Agar (MC), Blood Agar Plate (BAP), and Chocolate Agar Plate (CAP). The results revealed six bacterial isolates labeled FMCN-1 to FMCN-6 (FMCN denoting Fatmawati Market chicken nugget). Most isolates exhibited a moderate level of pathogenicity (FMCN-2, FMCN-3, FMCN-4, FMCN-5, and FMCN-6), with only one isolate demonstrating low pathogenicity (FMCN-1). In conclusion, storing chicken nuggets at room temperature for seven days can lead to bacterial contamination with mostly moderate pathogenicity. Further molecular analysis is required to identify the potentially harmful bacteria.
MECHANICAL ACTIVATION OF LIZARDITE BY DRY GRINDING FOR ENHANCED MINERAL CARBONATION
Authors:   Mining Engineering, Afyon Kocatepe University, Afyonkarahisar, Türkiye, Çiftçi Hakan
Published: November 2023

Mechanical activation of Ca/Mg silicates by grinding is a pre-treatment of some mineral carbonization processes. In this study, the mechanical activation of lizardite ore from a chromite beneficiation plant waste by grinding in a stirred media mill was studied. For grinding studies, grinding times of 10-20-30 min and stirring speeds of 600-800-1000-1200 rpm were the parameters investigated, while the ball charge rate was 60% and the ore charge rate was kept constant at 40%. This way, the effects of grinding time and stirring speed on particle size distribution and energy consumption were investigated. At the end of the grinding studies, the stirring speed was determined as 1200 rpm, and the grinding time was 10 min for the finer particle size distribution (d10: 2,7 µm, d50: 13,6 µm, d90: 57.6 µm) with less energy consumption (130.4 kWh/ton). FT-IR analyses proved that the samples were dehydroxylated by the milling process. As a result, according to the analysis performed after grinding, it can be said that the finer product obtained can be used in mineral carbonation processes.
EFFECT OF CRYOGENIC AND NATURAL AGING PROCESS APPLIED TO Al-Zn-Mg-Cu ALLOYS ON LIFE TIME CALCULATION
Authors:   Faculty of Technology, Department of Metallurgical and Materials Engineering, Gazi University, Ankara, Turkey, Altuntaş Gözde , Altuntaş Onur ,   Department of Warfare Weapons and Tools, Alparslan Defense Sciences and National Security Institute, National Defense University, Ankara, Turkey, Bostan Bülent ,   Faculty of Technology, Department of Metallurgical and Materials Engineering, Gazi University, Ankara, Turkey
Published: November 2023

In this study, life time calculation of aluminum 7075 alloy with cryogenic and natural aging processes was performed by thermal analysis. The aluminum alloy was quenched after solid solution treatment at 480°C and naturally aged for 10-100 days at room temperature (25°C). Other samples were cryogenically treated at -40°C and -80°C for 2 hours after solid solution treatment at 480°C. After the cryogenic treatment, natural aging was done at room temperature for 10-100 days. At the end of each period determined for the samples, the hardness values were measured. It was observed that there was no significant change in hardness values at the end of 10 and 100 days at -80 °C. Thus, it was determined that the natural aging process does not start after cryogenic treatment at -80 °C. It was observed that the hardness value of naturally aged samples after cryogenic treatment at -40 °C increased more than the natural aged samples only. This showed that -40 °C improved the mechanism by creating a driving force in the material. Life time calculations between 30 °C and 320 °C also showed that -40 °C cryogenic treatment + natural aging increased life time by approximately 20% compared to natural aging alone.
EFFECT OF METACOGNITIVE INTERVENTION STRATEGIES IN ENHANCING RESILIENCE AMONG PRE-SERVICE TEACHERS
Authors:   Research Scholar-Regular mode, Alagappa University College of Education, Faculty of Education, Alagappa University, Karaikudi-630 003, Tamil Nadu, India), Geetha KR. , Fathima Dr. M. Parimala ,   Assistant Professor, Alagappa University College of Education, Faculty of Education, Alagappa University, Karaikudi-630 003, Tamil Nadu, India
Published: November 2023

The arena of metacognition has been studied in various disciplines including education, psychology, positive psychology, and neuroscience, however, research studies have yet to address the role of metacognition in enhancing resilience. Thus, the present study explored how metacognitive intervention strategies enhance resilience among pre-service teachers. The understanding of resilience may act as a catalyst for pre-service teachers to overcome difficulties during and after their training period. An experimental method with a single group design was employed in this study and the sample was 20 pre-service teachers undertaking the Bachelor of Education course at Alagappa University College of Education, Alagappa University, Karaikudi, Sivagangai district, Tamil Nadu, India. The convenience sampling technique was utilized for this study. A metacognitive awareness questionnaire constructed and validated by the researcher and research supervisor with a Cronbach’s alpha reliability of the present sample is 0.72 and a Resilience Appraisal Scale (RAS) developed by Johnson et al., 2010 with Cronbach’s alpha reliability of the present sample is 0.75 were used for data collection. Results revealed that metacognitive intervention strategies influence the resilience of pre-service teachers and considerable improvement present in resilience among pre-service teachers after the experimentation period. Future research needs to focus on various dimensions of resilience for extensive knowledge and survey research would encourage measuring these constructs in the larger sample.
MARKET-BASED MANAGEMENT (MBM) APPROACH TO SUCCESS IN HIGHER EDUCATION: LESSONS FROM A MID-SIZED BUSINESS INSTITUTE
Authors:   Doctorate in Business Administration, Business Faculty, Amity University Dubai, UAE, Zaidi Dr. Uzma
Published: November 2023

This research examines a mid-sized business institute, SZABIST-Dubai by using a qualitative research methodology of case study. The research objective is to explore the adoption of Market-Based Management (MBM) for its application in Higher Education and to recommend Market Based Management that is lean and agile enough to identify local market opportunities, understand its unique requirements and initiate processes to capture these opportunities before they are lost to competition. Some significant findings of this paper are the survival and profitability challenges faced by SZABIST and a unidirectional centralised decision-making model that is adapted currently at the institute. The outcome of this paper is its proposition of Market Based Management (MBM) as a tool to evolve into a knowledge-based learning organization that is more responsive to regional and local challenges. The most significant contribution of this paper towards this objective is the founding of Task Teams that transform tacit learning into explicit knowledge through the process of socialisation. This paper may be useful for future researchers who wish to extend these findings to other higher educational institutes.
I Appreciate You: A Spectral Reading of SoTL during COVID-19
Authors: Facciolo Laura
Published: November 2023

What lives amongst loss? This study employs spectral reading practice to thematically analyze the scholarship of teaching and learning (SoTL) produced within the Canadian blogosphere during the COVID-19 pandemic. Despite the extent of loss that the pandemic brought, the findings of this study reveal that SoTL practitioners continued to embrace positive affectivities and “what works” in their reflective research about the experience of teaching and learning during crisis times. The four revealed themes—endless possibilities, teaching as care, care ethics, and community awe—point towards a hardening disciplinary and methodological characterization of SoTL (or what I refer to as a “SoTL attitude”) that is rooted in qualities of appreciation, generosity, and reparation. Overall, this work contributes to examinations of SoTL as an evolving disciplinary area, providing unique insights into its surprisingly cohesive response to the COVID-19 pandemic.
Induced pluripotent stem cells in periodontal reconstructive therapy: A narrative review of pre-clinical studies
Authors: Hendrawan Reza Dony , Prahasanti Chiquita , Savitri Irma Josefina , Hari Padmini
Published: November 2023

Background: Regenerative periodontal surgical therapy faces significant challenges due to the limited ability of the body to regenerate damaged periodontal tissue. One of the primary goals in regenerative periodontal therapy is regaining periodontal tissue attachment after destruction by periodontal disease. Currently, stem cells, harnessing three pivotal components—cells, biomaterials, and growth factors—are widely used in periodontal regeneration. Stem cells can be obtained from various sources, either by isolating cells from bone marrow, teeth, and muscles or through the somatic cell programming method (reprogramming) known as induced pluripotent stem cells (iPSCs). Purpose: This review aims to describe the potential use of iPSCs in the treatment of periodontal defects. Review: Search strategies were developed using the PubMed, LILACS, Scielo, and Wiley online databases during the period of 2012–2022. Ten articles met the inclusion criteria. iPSCs were obtained by inducing somatic cells from both dental and non-dental sources with factors Oct3/4, Sox2, Klf4, and c-Myc. Periodontal tissue regeneration procedures can be augmented with iPSCs. Unlike tooth-based stem cells, iPSCs offer several advantages, such as unlimited cell sources and the capability to differentiate into any cell type, including periodontal tissue. The potential of iPSCs extends to correcting periodontal bone defects and forming new periodontal tissues, such as alveolar bone, cementum, and periodontal ligament. However, iPSCs do have limitations, including the need for clinical trials, cell programming production facilities, and optimization of differentiated-cell functionality. Conclusion: The combined use of iPSCs in cell-based tissue engineering holds vast potential for future periodontal treatment strategies.
The covert Narcissism on Social Anxiety in Early Adulthood: The Mediating Effects of Perfectionistic Self-presentation and Avoidance of Experience
Authors:   The Association of Korea Counseling Psychology Education Welfare, SONG Sun-Hwa
Published: November 2023

This study was conducted to examine the structural relationships between covert narcissism inearly adulthood and social anxiety, using perfectionistic self-presentation and experientialavoidance as mediating variables. An online survey was administered to 410 domestic earlyadults (aged 19-35), and the collected data were analyzed using descriptive statistics, correlationanalysis, and structural equation modeling. The results of this study are as follows: First, thedirect mediating effect of perfectionistic self-presentation on the relationship between covertnarcissism and social anxiety was not significant. Second, the direct mediating effect ofexperiential avoidance on the relationship between covert narcissism and social anxiety wassignificant. Third, the mediating effect of perfectionistic self-presentation on the relationshipbetween covert narcissism and social anxiety was not significant, while the mediating effect ofexperiential avoidance was significant. Based on the above results, we discussed implicationsand recommendations for further research.
Mediating Effects of Happiness and Executive Function Difficulty on the Relationship between Children's Grit and School Adjustment
Authors:   The Association of Korea Counseling Psychology Education Welfare, LEE Na-Yung
Published: November 2023

This study was to investigate the dual mediating effects of happiness and executive functiondifficulty on the relationship between children's grit and school adjustment. The subjects of thisstudy were 1,397 children in 6th grade of elementary school. The data were drawn from the13th(T5) wave data(2020) of the Panel Study on Korean Children (PSKC). Data processing wasperformed using the IBM SPSS 26 program and Hayes (2013) Macro Process (Model 6) for thecorrelation and dual mediating effect among relevant variables. The results of study are asfollows. First, children's grit had a direct effect on school adaptation in a path model includingchildren's happiness and executive function difficulties. Second, happiness mediated the effectof children's grit on school adaptation. Third, executive function difficulties mediated the effectof children's grit on school adaptation. Fourth, the effect of children's grit on school adaptationwas double mediated in the order of happiness and executive function difficulties. Inconclusion, children's grit could positively influence children's school adjustment by sequentiallyaffecting the emotional factor of happiness and the cognitive behavioral control factor ofexecutive functioning difficulties. Limitations of the study and suggestions were discussed.
The Effect of Perceptions of University Education on Positive and Negative Emotions among Young Workers in the Service Industry
Authors:   The Association of Korea Counseling Psychology Education Welfare, CHI Myong-Won , LEE Kang-Wook , LEE Ju-Yeon
Published: November 2023

This study was conducted to identify the correlation between University Education, positiveemotions, and negative emotions recognized by young workers in the service industry, and tofind the direction of university education, enhance positive emotions, and ease negativeemotions. For the study, 225 copies of the 2021 Youth Social and Economic Status Surveysurveyed by the Korea Youth Policy Institute were analyzed. As a result of the study, there wasa correlation between perception of university education, positive emotions, and negativeemotions. In addition, it was confirmed that the higher the perception of college education byyoung service workers, the higher the positive emotion and the lower the negative emotion. Accordingly, it was proposed that an approach is needed at the social level to the problemsexperienced by young workers.
The Relationship between Childhood and Adolescent Complex Trauma Experience and Interpersonal Problems: Mediating Effects of Self-Concept and Maladaptive Cognitive Emotional Regulation
Authors:   The Association of Korea Counseling Psychology Education Welfare, PARK Hyun-Seon
Published: November 2023

This study tends to examine the mediating effects of self-concept and maladaptive cognitiveemotion regulation on the relationship between child and adolescent complex traumaticexperiences and interpersonal problems. In order to test this hypothesis, this study wasconducted with 621 male and female college students and graduates from universities in SouthKorea whose ages are from ages 18 to 29. The research analysis results are as follows. theresult of the analysis of the mediating effects of maladaptive cognitive emotion regulation andself-concept on the relationship between child and adolescent complex trauma and interpersonalproblems showed mediating effect. Among these, it was confirmed that the indirect effect ofself-concept had a greater influence. This study sought to utilize the two variables as therapeuticresources in trauma research and discussed follow-up research and suggestions.
The Relationship between Counselors’ Insecure Adult Attachment and Working Alliance: Mediating Effect of Countertransference Management Moderated by Focusing Manner
Authors:   The Association of Korea Counseling Psychology Education Welfare, NAM Se-Eun , LEE Young-Ae
Published: November 2023

This study examined the moderated mediating effect of Focusing manner on the relationshipbetween counselors' insecure adult attachment, countertransference management, and workingalliance. The subjects of the study were 308 youth and adult counselor. As a result of thestudy, first, the significant partial mediating effect of countertransference management in therelationship between insecure adult attachment and working alliance was verified. Second, themoderating effect of focusing manner was found to be significant in the relationship betweenthe counselor's insecure adult attachment and countertransference management. Third, amoderated mediating effect of focusing manner appeared in the path from the counselor'sinsecure adult attachment to the working alliance through countertransference management. Thisstudy tried to confirm counselor's personal and professional characteristics that predict thequality of the working alliance, and discussed limitations and suggestions for the future study.
Consensual qualitative study on chat counseling experiences of youth chat counselors
Authors:   The Association of Korea Counseling Psychology Education Welfare, KIM Eun-Young , LEE Sang-Hee
Published: November 2023

Recently, the growth of chat counseling has been remarkable, and the preference among theyouth is increasing significantly. At present, it could be the most professional for a counselorwith counseling license to participate in chat counseling. Accordingly, this study targetedcounselors who hold professional licenses and participate in chat counseling and looked indepth at what they experience during chat counseling. After conducting interviews with 12 chatcounselors for youth and analyzing them using a consensual qualitative research method, 4areas, 13 categories, and 33 subcategories were derived. Looking at the four areas, they were‘experience before chat counseling’, ‘experience during the chat counseling’, ‘understanding thecharacteristics of chat counseling’, and ‘development tasks of chat counseling’. Participantsreported that chat counseling can be an effective intervention method for the youth. This studywill provide practical, helpful information and materials to counselors who are entering chatcounseling.
Front Matter
Authors: Prasetiadi Agi
Published: November 2023

Jurnal INFOTEL
TOWARDS UNDERSTANDING TRUE AND VERIFIABLE KNOWLEDGE IN THE FRAMEWORK OF COGNITIVE LINGUISTICS AND COGNITIVE TERMINOLOGY SCIENCE (in memoriam of Valentina Novodranova)
Authors:   Lomonosov Moscow State University, Manerko L.A.
Published: November 2023

On August 14 in 2023 Valentina Novodranova, an amazing person and teacher, a terminologist and a specialist in classical philology, an outstanding scientist and the author of more than 260 scientific works published in our country and abroad, passed away. She was the founder of the field of research known as Cognitive Terminology. In her works, we can find insights on the properties of terms and their cognitive nature, on linguistic peculiarities as a means of access to the cognitive database of specialists in certain domains of knowledge. She wrote about professional experience and special kinds of knowledge used in some particular activity of a person and organisation of terminological systems, her ideas tackled with medical terminology and certain knowledge structures characterising this specialised sphere of activity. The most important thing is that it is impossible to describe language and cognitive mechanisms in a deep way without paying attention to dynamic processes in the language system and in close connection with the functioning of linguistic means in specialised discourse. In this article another sphere of interest of Valentina Novodranova is revealed - it is her profound understanding of the philosophy of human experience and cognition. It is connected with the recognition of true and reliable knowledge, thanks to which a scientist is able to achieve success in the cognitive and discursive perspective of terminology science, as well as to present the fundamentals of the source and development of medical knowledge peculiarities. Valentina Novodranova was the keeper of the traditions of the outstanding research school in Russia, which brought together friends from near and far, from home and abroad. A kind and beautiful woman, she was open to new discoveries, gave the joy of warmth and communication. We were always amazed by her tireless energy, her joy of discovery and her desire to share it with others, her ability to lead her students, colleagues and companions.
COGNITIVE BASIS FOR THE VARIATION OF RECURRENT GESTURES IN EXPLANATORY DISCOURSE: PALM-UP-OPEN-HAND AND PALM-DOWN-OPEN-HAND GESTURES
Authors:   Moscow State Linguistic University, Iriskhanova O.K. , Nikolayeva A.I. ,   Moscow State Linguistic University
Published: November 2023

The paper provides the results of the analysis of recurrent gestures (palm-up-open-hand and palm-down-open-hand) used in Russian spoken explanatory discourse. It is argued that mimetic schemas which imitate various manipulations with objects and are directly linked to embodied cognition, can be used as efficient tools for cognitive analyses of gesture variation. Following a set of formal criteria (configuration of the palm, a static / dynamic phase in the stroke, direction of the hand movement, boundedness or unboundedness of a gesture), the authors differentiate between general and specific mimetic schemas that form the cognitive basis for the palm-up-open-hand and the palm-down-open-hand gestures and their variants (subtypes). With the help of qualitative and quantitative methods and procedures, correlation between cognitive (mimetic) and functional features of the gestures is investigated. The authors demonstrate that there is significant difference in distribution of the mimetic PUOH and PDOH schemas and their subtypes, and there is direct and strong correlation between the mimetic schemas and the functions realized through them in the explanatory discourse.
COMMUNICATIVE-STRUCTURAL SYNTAX AS REFLECTED IN THE INTERACTIONS OF SYSTEM-CENTRIC AND ANTHROPOCENTRIC APPROACHES TO LANGUAGE
Authors:   Derzhavin Tambov State University, Sharandin A.L.
Published: November 2023

The article presents a topical issue for the modern theory of language about the relationship between language and communication in the context of the outstanding syntaxist S.G. Ilyenko’s grammatical theory. The author of the article substantiates the approach, according to which the sentence is not only a unit of the syntactic level, but also a part of communication as its integrated member. As a result, a holistic communicative-structural representation of syntax is formed both as a structural level (system-centric aspect) and as a communicative tool for use in interpersonal communication (anthropocentric aspect). A cognitive view is presented on the fundamental difference between articulated and non-articulated sentences, which have a different nature of their formation - structural-semantic and communicative-semantic. But within the framework of the textual approach, their integration makes it possible to comprehend not so much the opposition of syntax and communication as different levels, but rather their interaction. This allows us to see in integration the main principle of describing the syntactic system - structural and communicative. This position reflects the nature of the modern stage of scientific knowledge of the language and is in accordance with the concept of consistency in relation to syntax and communication.
Research on Non-intrusive Load Recognition Algorithm Based on High Frequency Signal Decomposition with Improved VI Trajectory and Background Color Coding
Authors: Shi Jiachuan , Zhi Dingrui , Fu Rao
Published: November 2023

Against the backdrop of the current carbon peaking and carbon neutrality policies, higher requirements have been put forward for the upgrading and construction of smart grids. Non-intrusive load monitoring (NILM) technology is a key technology for advanced measurement systems at the end of the power grid. It obtains detailed power information of the load, without the need for traditional hardware deployment. The key step to solve this problem is load decomposition and identification. This paper first utilized Long Short Term Memory-Denoising Autoencoder(LSTM-DAE) to decompose the mixed current signal on the household busbar and obtain the current signals of multiple independent loads that constituted the mixed current. Then, the obtained independent current signals were combined with voltage signals to generate multi-cycle colored Voltage-Current(VI) trajectories, which were color-coded according to the background. These colored VI trajectories with background colors formed a feature library. When the CNN network was used for load recognition, considering the influence of hyperparameters on recognition results, the BOA algorithm was used for optimization, and the optimized CNN network was employed for VI trajectory recognition. Finally, the proposed method was validated using the PLAID dataset. Experimental results showed that the proposed method exhibited better performance in load decomposition and identification.
Numerical Solving of the Partial Generalized Symmetric Eigenproblems for Piezodevices with the Shift-and-Invert Lanczos Method
Authors: Martynova Tatiana , Muratova Galina , Oganesyan Pavel
Published: November 2023

In the research we consider a structure-fluid interaction of oscillating piezodevice and acoustic liquid. Such problem requires finding resonance or anti-resonance frequencies of the solid structure to use them in the latter frequency-response analyses step. After finite element discretization of the issue, we need to solve a generalized eigenvalue problem (GEP). The most efficient numerical method for solving the partial GEP is the shift-and-invert Lanczos method. Each step of this algorithm requires solving a large scale system of linear algebraic equations (SLAEs) with special properties. Various ways of ordering grid nodes lead to coefficient matrices with different structure. Several methods are compared in terms of efficiency. The results of the numerical experiments are presented.
Operative Management of Digestive Duplications in Children
Authors: Alqadi Gratiana Oana , Balanescu Laura
Published: November 2023

The study aimed to review the management of pediatric digestive duplications (DD) with regards to clinical presentation, operative procedures and complications in a single institution in Bucharest, Romania. A retrospective analysis was performed using patient records from ‘Grigore Alexandrescu’ Emergency Children’s Hospital from 2013 to 2023. All patients with a postoperative diagnosis of DD were selected. A total of 39 children (19 boys, 20 girls) with DD have been treated in our hospital in the past 10 years. Only N=5 of them have been diagnosed antenatally. In N=22 cases patients were referred to our hospital for tumors, while N=17 cases involved an acute setting. Comorbidities were encountered in N=16 patients. Duplications involved several parts of the digestive tract: ileal (N=19), colonic (N=10), esophageal (N=2), jejunal (N=2), gastric (N=2), duodenal (N=1), ileocecal (N=1), esogastric (N=1) and rectal (N=1). Two of the duplications were intraluminal, while the rest were cystic. There were N=28 open interventions and N=11 laparoscopies. Conversion was needed in N=2 cases due to (a) overdistended bowel and (b) dense adhesions between the ileum and the tumor. The tumor was resected in N=17 cases, while intestinal resection was required in N=22 cases. A drain was used in N=21 patients. The average hospital stay for open procedures was 10 days and for laparoscopic procedures 8 days. Complications arose in N=7 patients who had an open procedure and N=1 patient who had a laparoscopic procedure. There were no mortalities. With a low rate of antenatal diagnosis (12.82%), 43.58% of DD appeared in an acute setting. Open procedures were favored in acute cases and patients with comorbidities, but required a longer hospital stay. Laparoscopic management had a 18.18% conversion rate and a low rate of complications (9.09%).
Thermophysical and Transport Properties of Deep Eutectic Solvent Mixtures Containing Pure Choline Chloride/Ethylene Glycol with a Mole Ratio of 1:4 and Mixed with LiPF6 for Application in Redox-flow Batteries
Authors: Zargari Shastan Farshid , Nowroozi Alireza
Published: November 2023

Redox-flow batteries are rechargeable batteries that store energy in two liquid electrolytes, separated by a membrane. During charging and discharging, the electrolytes flow through the membrane and undergo chemical reactions that generate or consume electrical energy. These batteries are known for their scalability and long cycle life and are versatile energy storage technologies developed to enhance efficiency and lower costs. Deep Eutectic Solvents (DES) are eco-friendly alternatives to traditional electrolytes, and their properties have been studied to improve the performance of redox-flow batteries. We investigated choline chloride/ethylene glycol (ChlCl/Eg) mixtures with LiPF6 salt at four concentrations through experimental and MD simulations. The thermophysical and transport properties of the mixture, including density, diffusion coefficient, viscosity, and ionic conductivity, were calculated across a temperature range of 298.15–398.5 K. Our findings indicate that an increase in salt concentration leads to a decrease in diffusion coefficients and ionic conductivity, while increasing the viscosity of the deep eutectic solvent. This research provides valuable insights into the behavior of DES mixtures and can aid in the design and optimization of DES-based processes for use in redox-flow batteries.
Parenteral Iron Therapy for Pediatric Patients
Authors: Mantadakis Elpis , Alexiadou Sonia , Zikidou Panagiota
Published: November 2023

Iron deficiency (ID) is by far the most common nutritional disorder in developing and developed countries. When left untreated, ID leads to anemia. Although the usual recommended treatment for iron deficiency anemia (IDA) is oral iron therapy with countless products, such therapy necessitates administration for >3-6 months with questionable patient compliance since most oral iron products have an unpleasant metallic aftertaste and cause intestinal side effects. In addition, in certain gastrointestinal conditions, such as inflammatory bowel diseases or untreated gluten-sensitive enteropathy, oral iron therapy is contraindicated or unsuccessful. Intravenous iron is considered safe in adults, where adverse events are mild and easily managed. The experience with parenteral iron in children is much more limited and many pediatricians appear reluctant to use it because of uncorroborated fears of serious anaphylactic reactions. In the current article, we thoroughly review the available pediatric literature on the use of all commercially available parenteral iron products except ferumoxytol, which was recently removed from the market. We conclude that parenteral iron appears to be safe in children, it works faster than oral iron and the newer third-generation products allow replacement of the total iron deficit at a single setting.
Frequent Errors in Modeling by Machine Learning: A Prototype Case of Predicting the Timely Evolution of COVID-19 Pandemic
Authors: Héberger Károly
Published: November 2023

Background: The development and application of machine learning (ML) methods became so fast that almost nobody can follow their developments in every detail. There is no wonder that numerous errors and inconsistencies in their usage have also spread with a similar speed independently from the tasks: regression and classification.. This work summarizes frequent errors committed by certain authors with the aims of helping scientists to avoid them. Methods: The principle of parsimony governs the train of thought. Fair method comparison methods can be completed with multicriteria decision making techniques, preferably sum of ranking differences (SRD). Its coupling with analysis of variance (ANOVA) decomposes the effect of several factors. Earlier findings are summarized in a review-like manner: the abuse of the correlation coefficient and proper practices for model discrimination are also outlined. Results: Using an illustrative example, the correct practice and the methodology is summarized as guidelines for model discrimination, and for minimizing the prediction errors. The following factors are all prerequisites for successful modeling: proper data preprocessing, statistical tests, suitable performance parameters, appropriate degrees of freedom, fair comparison of models, outlier detection, just to name a few. A checklist is provided on how to present ML modeling properly. The advocated practices are reviewed in the discussion. Conclusions: Many of the errors can easily be filtered out with careful reviewing. The authors’ responsibility is to adhere to the rules of modeling and validation.
Pengembangan Strategi Branding, Pemasaran Online, Dan Peningkatan Kualitas Laporan Keuangan Pada Usaha Catering Dapoer Adiba
Authors: Ermawati Nanik Ermawati , Hidayanti Alfiyani Nur , Salisa Naila Rizki
Published: November 2023

Dampak pandemi Covid-19 terhadap perekonomian sangatlah besar termasuk diantaranya pada usaha bisnis catering. Permintaan jasa catering yang menurun mengharuskan pelaku usaha untuk dapat memutar otak agar bisnis yang dijalankan dapat tetap bertahan pada masa pandemi Covid-19 seperti saat ini. Pemasaran secara online lebih  prospektif karena memungkinkan para calon pelanggan dan pengguna jasa catering memperoleh informasi lebih cepat mengenai produk dan jasa yang diberikan. Selain pemasaran secara online, strategi branding juga sangat diperlukan para pelaku UMKM. Strategi branding dan pemasaran online memudahkan para pelaku UMKM sekaligus konsumen dalam melakukan penjualan online. Tujuan dari pengabdian ini adalah memberikan pendampingan pelatihan pemasaran online dan juga cara melakukan strategi branding pada usaha catering Dapoer Adiba yang terletak di Kota Jepara. Selain itu pelaku usaha juga diberikan keterampilan membuat laporan keuangan berbasis sistem sederhana dengan menggunakan Microsoft Excel agar keuangan usaha dapat terkontrol secara sistematis dan terpercaya. Setelah melakukan pengabdian ini diharapkan pelaku usaha catering Dapoer Adiba dapat tetap meningkatkan penjualan dan semakin maju dalam menjalankan usaha bisnisnya.
Memperindah Ruang Publik dengan Taman dan Seni Mural sebagai Media Edukasi Sosial Kemasyarakatan
Authors: Pamungkas Satria Aji , Suryanti Venty
Published: November 2023

Kuliah Kerja Nyata (KKN) Tematik Integratif Universitas Sebelas Maret (UNS) Surakarta Kelompok 129 dilaksanakan pada bulan Januari-Februari 2021 di RW XI Kelurahan Sangkrah, Kecamatan Pasar Kliwon, Kota Surakarta dengan judul Program Sadar Lingkungan dan Pemberdayaan Warga Kelurahan Sangkrah, Surakarta di Masa Pandemi COVID-19. Kelurahan Sangkrah terletak di daerah bantaran Sungai Bengawan Solo yang belum dikelola dengan baik. Daerah ini merupakan daerah padat penduduk dan kumuh, dimana rumah informal banyak ditemui di sekitar bantaran Bengawan Solo. Salah satu program KKN yang telah dilaksanakan adalah (1). sosialisasi pentingnya menjaga kebersihan dan keindahaan lingkungan dan (2). pelaksanaan kegiatan pemanfaatan lahan kosong di sekitar tanggul untuk dibuat taman serta membuat karya seni mural di dinding tanggul. Kegiatan ini diikuti dengan sangat antusias oleh warga masyarakat, dimana seluruh warga yaitu remaja, ibu-ibu dan bapak-bapak berkontribusi nyata untuk membuat indah lahan kosong dan dinding di tanggul bantaran Sungai Bengawan Solo. Hasil dari program kerja taman hias dan mural ini telah membuat perbedaan yang signifikan terhadap pemandangan sekitar Kelurahan Sangkrah RW XI. Seni mural bertemakan kampung KB membuat fungsi taman sebagai media edukasi. Di lokasi taman telah juga dimanfaatkan sebagai fungsi sosial yaitu sebagai tempat refreshing atau olah raga bagi warga serta tempat bermain bagi anak-anak. Fungsi ekonomi dari taman dapat terlihat dari pemanfaatn tanaman sayuran dan tanaman obat keluarga (TOGA) oleh warga masyarakat. Tanaman buah-buahan juga ditanam di lahan kosong tersebut, sehingga selain sebagai peneduh dan membuat udara segar atau bersih juga dapat dimanfaakan buahnya kelak dikemudian hari jika pohon sudah besar dan berbuah.
Entity and Entity Type Composition Representation Learning for Knowledge Graph Completion
Authors: Ni Runyu , Shibata Hiroki , Takama Yasufumi
Published: November 2023

This paper proposes a simple knowledge graph embedding (KGE) framework that considers the entity type information without additional resources. The KGE is used to obtain vector representations of entities and relations by learning structured information in triples. The obtained vectors are used to predict the missing links in a knowledge graph (KG). Although many KGs contain entity type information, most of the existing methods ignored the potential of the entity type information for the link prediction task. The proposed framework, which is called entity and entity type composition representation learning (EETCRL), obtains vector representations of both entities and entity types, which are combined and used for link prediction. Experimental results on three datasets show that the EETCRL outperforms the baseline methods in most cases. Furthermore, the results obtained from tests with different model sizes show that the proposed framework can achieve high performance even with a small model size. This paper also discusses the effect of considering information about entity types on the link prediction task by analyzing the experimental results.
Predicting Student Performance Through Data Mining: A Case Study in Sultan Ageng Tirtayasa University
Authors: Alfanz Rocky , Hendrianto Raphael Kusumo , Siagian Al Hafiz Akbar Maulana
Published: November 2023

Failure in compulsory subjects such as chemistry, calculus, physics, and basic control systems could hamper the graduation process of students. Thus, students must be successful in such obligatory courses. To address this issue, this study aims to predict student performance based on their learning outcomes using data mining techniques. In particular, we utilize decision tree (DT), k-nearest neighbor (KNN), support vector machine (SVM), and naive Bayes (NB) algorithms to predict student performance. The data for this study were gathered from the learning outcomes of students in the basic control systems course and subsequently modeled using binary and nine-level classifications. The experimental results showed that DT could perform better than KNN, SVM, and NB in the binary and nine-level classifications. Interestingly, the results of DT (i.e., the prediction values) are almost similar to those of the original values of the basic control systems course.
Three clusters of grammatical abilities in individuals with language deficits “split” the universal grammar hypothesis
Authors: Vyshedskiy Andrey , Venkatesh Rohan , Khokhlovich Edward
Published: November 2023

In this study we assessed 15 language comprehension abilities in 55,558 individuals with language deficits 4 to 22 years of age using parent-generated reports. Data-driven cluster analysis identified three distinct clusters of co-expressed abilities. The first cluster, termed “command language,” included knowing the name, responding to ‘No’ or ‘Stop’, responding to praise, and following simple commands. The second cluster, termed “modifier language,” included understanding color and size modifiers, several modifiers in a sentence, size superlatives, and numbers. The third cluster, termed the “prepositional language,” included understanding of spatial prepositions, verb tenses, flexible syntax, possessive pronouns, explanations about people and situations, simple stories, and elaborate fairy tales. Independently, we performed data-driven cluster analysis of participants. 19.8% of participants were limited to command language phenotype; 58% of participants were limited to modifier language phenotype; 22.2% of participants were clustered to the most-advanced prepositional phenotype. All neurotypical participants were clustered to the prepositional phenotype. While the Universal Grammar hypothesis attempts to preach a dichotomy between the presence of grammatical abilities in humans and their absence in animals, this study shows that there are additional distinct language comprehension phenotypes that require an explanation.
ZNF276 and WIZ are CRBN neosubstrates involved in the anti-angiogenic activity of thalidomide and immunomodulatory drugs
Authors: Ito Takumi , Asatsuma-Okumura Tomoko , Endo Akinori , Yamamoto Junichi , Iwai Yoshiko , Yamaguchi Yuki , Naito Mikihiko , Handa Hiroshi , Saeki Yasushi
Published: November 2023

Thalidomide was once developed as a sedative but had been withdrawn from the market in the 1960s because of its serious teratogenicity. Currently, this drug is reevaluated and used for the treatment of multiple myeloma, and many derivatives such as lenalidomide and pomalidomide have been developed. CRBN is a primary target of thalidomide and its derivatives and forms an E3 ubiquitin ligase complex with DDB1 and CUL4. Although the basic mechanism of action of thalidomide is quite well understood, a long-standing question remains regarding its inhibitory effect on angiogenesis. Here, we employed a comprehensive proteomic approach using thalidomide-treated endothelial cells to identify ZNF276 and WIZ as CRBN neosubstrates. Thalidomide and its derivatives exert their anti-angiogenic effects through these two zinc finger proteins, resulting in the downregulation of FABP4. This study reveals the CRBN neosubstrates involved in thalidomide-induced anti-angiogenesis and provides attractive therapeutic targets of CRBN-based protein degraders.
Antifungal Susceptibility of Pathogenic Moulds isolated from patients at Tertiary Hospital in South western Uganda
Authors: Bazira Joel , Nalumaga Pauline , Tuhamize Barbra , Orishaba Francis , Frederickson Wasswa , Taseera Kabanda
Published: November 2023

Fungal infections are common in tropical regions causing diverse human infections. Their isolation and sensitivity testing plays a major key role in the clinical management. Samples from eye clinic, skin scrapings and nail clippings were obtained and stained with potassium hydroxide, observed at 40x objective lens for hyphae identification. They were inoculated onto potato dextrose agar slant and incubated for 14 days for mould isolation. Lactophenol cotton blue stain was used for macroscopic identification of Moulds. 3 antifungal powder agents were dissolved in RPMI-1640 solution for the MIC of the isolated Moulds. Of 40 Moulds isolated 30(75%) were skin scrapings, 5(12.5%) were corneal scrapings and 5(12.5) were nail scrapings. Of these isolates; 10 Aspergillus niger, 6 Penicillium, 5 Trichophyton mentagrophytes, 4 Curvularia, 5 Rhizopus, 4 Fusarium, 1 Bipolaris and fusarium, 1 Lasidiopolidia, 1 Collectrium, 2 Aspergillus fumigatus, 1 Aspergillus flavus. For MIC, Itraconazole had 39 sensitive and 1 resistant, Fluconazole had 35 sensitive and 5 resistant while Amphotericin B had 32 sensitive and 8 resistant isolates. Amphotericin B increased resistance is attributed to readily available polyene creams in the drug shops across Uganda.
ALKBH5-mediated m6A modification of circFOXP1 promotes gastric cancer progression by regulating SOX4 expression sponging miR-338-3p
Authors: Wang Shouhua , Zhu Xiang , Hao Yuan , Su Tingting , Shi Weibin
Published: November 2023

Circular RNAs (circRNAs) have recently been found as potential functional modulators of the cellular physiology processes in gastric cancer (GC). However, the potential clinical significance and molecular mechanisms of circRNAs involved in the development of GC remain largely unknown. In the study, we demonstrated that circFOXP1 was highly expressed in GC tissues compared with adjacent normal tissues. Higher circFOXP1 expression positively associated with tumor size, lymph node metastasis, TNM stage and poor prognosis in patients with GC. Multivariate Cox analysis revealed that higher circFOXP1 expression was an independent risk for the disease-free survival (DFS) and overall survival (OS) of GC patients. Functional studies showed that higher circFOXP1 expression promoted cell proliferation, cell invasion, and cell cycle progression in GC in vitro. In vivo, knockdown of circFOXP1 inhibited tumor growth. Mechanistically, by double luciferase reporter, Methylated RNA immunoprecipitation (MeRIP), RNA binding protein immunoprecipitation assay and RNA pull-down assays, we clarified that circFOXP1 was under m6A-modification mediated by ALKBH5 in GC cells. Besides, circFOXP1 promoted GC progression by regulating SOX4 expression sponging miR-338-3p in GC cells. In conclusion, our findings highlight that circFOXP1 could serve as a novel diagnostic and prognostic biomarker and potential therapeutic target of GC treatment.