bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Moderate Physical Exercise on the Rheological and Biochemical Properties of Blood in Osteoarthritis Patients Who Are Regular Winter Swimmers
Authors: Strzelczyk Małgorzata , Teległów Aneta , Marchewka Jakub , Ptaszek Bartłomiej , Marchewka Anna
Published: April 2021

The aim of this study was to assess the influence of moderate physical exercise on selected blood parameters in regular winter swimmers who suffer from osteoarthritis. The study covered a period of 6 months, from November to April, and was carried out on 17 women and 22 men. The participants
were divided into 4 groups: Female CWI – women who only immersed themselves in cold water, Female CWI + PE – women who exercised in addition to water immersion, Male CWI – men who only immersed themselves in cold water, and Male CWI + PE – men, who exercised in addition
to water immersion. Venous blood was collected twice, before and after the exercise program. A statistically significant decrease in fibrinogen, plasma viscosity, T ½ , and AMP was observed in the blood of people who did not take part in the physical exercise program while a significant
decrease in cortisol levels was observed in the people who participated in the exercise program in addition to cold water immersion. In terms of rheological parameters, a significant increase in the elongation index (EI) of erythrocytes from shear stress 2.19 Pa in all groups was observed.
There were no statistically significant changes in AI in all groups. Physical activity has an influence on the blood parameters of elderly winter swimmers suffering from osteoarthritis.
Creencias docentes: El enfoque de género en la educación y la educación sexual en secundaria
Authors: Rodríguez Reyes Andrea Lucia , Pease Dreibelbis María Angélica
Published: April 2021

Esta investigación tuvo como finalidad explorar las creencias docentes sobre el enfoque de género en la educación y la educación sexual de un grupo de docentes de secundaria de una institución educativa pública de la provincia de Cañete. Para ello, se aplicó una entrevista a profundidad a seis docentes —tres hombres y tres mujeres—, distribuida en dos áreas de creencias docentes: una sobre educación sexual y otra sobre el enfoque de género en la educación. Los resultados muestran tres creencias docentes predominantes conservadoras en relación con la sexualidad, el sexo y el género, que influyen en cómo entienden la educación sexual y el enfoque de género: la sexualidad es principalmente biológica, sexo y género son lo mismo, y la homosexualidad es anormal. Estas creencias promueven la reproducción de modelos de riesgo y moralistas para abordar la educación sexual y una visión negativa sobre el enfoque de género en la educación. De acuerdo con las creencias de este grupo de docentes, dicho enfoque buscaría “homosexualizar” a sus estudiantes, a pesar de que lo planteado en las entrevistas muestra un discurso de equidad entre hombres y mujeres, desde el cual el enfoque de género sería adecuado. Así, existe un enfoque inclusivo binario que funciona, pero las identidades de género son más difíciles de asumir. El estudio, también, ha identificado tres creencias docentes diferentes a las predominantes, desde un enfoque más integral: el respeto a personas con orientación sexual distinta a la heterosexual, la necesidad de hablar sobre educación sexual en el aula, y la importancia de la igualdad de oportunidades para hombres y mujeres.
Cursos de vida y perfiles biográficos de adolescentes en situación de abandono escolar
Authors: Cavagnoud Robin
Published: April 2021

El artículo propone un modelo de interpretación del abandono escolar de adolescentes de ambos sexos, a partir del enfoque del curso de vida y de un análisis de datos biográficos. Para ello, se fundamenta en una observación del entrelazado entre las trayectorias individuales, familiares e institucionales, y de los factores de vulnerabilidad que condicionan el abandono del sistema educativo. Mediante una investigación de corte cualitativo, constituida de historias de vida realizadas en una muestra de 33 adolescentes de 3 departamentos del Perú (Lima, Ayacucho y Pucallpa), el análisis de los resultados evidencia un conjunto de perfiles biográficos que confirman la diversidad del fenómeno. El modelo propuesto muestra que, en algunos casos, el abandono es el resultado de un proceso que se manifiesta por un deterioro progresivo e inalterado de la relación entre los adolescentes, la familia y la institución escolar, mientras que, en otros casos, se trata de la consecuencia de un evento detonante que marca una ruptura en el curso de vida de los adolescentes.
The Effect of Financial Constraints and Institutional Ownership on Tax Agressiveness
Authors: Rachmawati Nurul Aisyah , Fitriana Ana
Published: April 2021

Tax aggressiveness is an action taken by a company in reducing taxable income through tax planning, either legally done by tax avoidance or illegally by tax evasion. This study examines the effect of financial constraints and institutional ownership on tax aggressiveness.The population in this study are manufacturing companies listed on the Indonesia Stock Exchange for the period 2016-2018. The sampling method used in this research is purposive sampling, with this method companies that meet as many as 56 companies. The analytical tool used is classic assumption test, multiple linear regression test, model test and hypothesis test. The results of this study indicate that (1) financial constraints have a positive effect on tax aggressiveness, (2) institutional ownership has a positive effect on tax aggressiveness, (3) institutional ownership weakens the relationship between financial constraints and tax aggressiveness.
ANALYZE FACTORS THAT AFFECT ENTREPRENEURS OF MICRO, SMALL, MEDIUM ENTERPRISES INTENTION TO USE ACCOUNTING INFORMATION SYSTEMS BASED ON FLOW THEORY
Authors: Debbianita Debbianita , Wijaya I Nyoman Agus , Lingga Ita Salsalina , Maria Maria
Published: April 2021

This study aims to analyze factors that affect entrepreneurs of micro, small and medium enterprises (MSME) intention to use accounting information systems (AIS). This research model is based on theory of flow which analyzes attitude towards AIS Use, Perceived Enjoyment and Concentration as factors that affect behavioral intention to use and its impact to actual usage. Analysis of data uses Partial Least Square (PLS) of Structural Equation Modeling (SEM). Unit of analysis in this research are entrepreneurs of Micro, Small, and Medium Enterprises (MSME) in Bandung City. In order to obtain primary data, we use questionnaires. The result of this research is intended to solve the problem of low intention to use AIS which gives impact to AIS usage.
THE EFFECT OF CORPORATE SOCIAL RESPONSIBILITY DISCLOSURE ON PROFITABILITY AND COMPANY VALUE
Authors: Angela Aurora , Hidayat Vinny Stephanie , Oktavianti Oktavianti
Published: April 2021

This study aims at determining the effect of CSR disclosure on profitability and company value. This study uses the population of all companies included in the LQ45 group listed on the IDX for three consecutive years, namely 2017, 2018, and 2019. The technique to test the hypothesis is Simple Linear Regression Analysis. It is used to determine the effect of CSR disclosure on profitability and the effect of CSR disclosure on company value.The result of this study is the disclosure of CSR does not have a significant effect on profitability neither does it affect the company value. Despite the fact that the results show that CSR disclosure does not have a significant effect, the authors suggest that companies continue carrying out CSR activities because it is a long-term investment activity.
DETERMINANT FACTORS THAT INFLUENCE THE ORIGINAL INCOME OF THE VILLAGE
Authors: Arini Farida Rika , Icih Icih , Putri Trisandi Eka
Published: April 2021

This study aims to determine the factors that influence the original income of the village. The objects in this study are villages in the Subang Districts area. This research is a quantitative study using secondary data types. The sample selection technique uses purposive sampling to produce 103 villages. The results showed that: (1) Village financial management partially has a significant positive effect on village original income, (2) Village building index partially has no effect on the original income of the village, (3) education level of the apparatus of the village government partially did not have effect on village original income, (4) Village consultative bodies partially do not affect the village's original income, (5) village financial management, village building index, education level of the apparatus of the village government and village consultative bodies simultaneously have a significant effect on village original income.
Tensión de rotura. Un panorama expositivo de 2019
Authors: Martín Larumbe Míreya
Published: April 2021

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Entrevista a Tomás Yerro Villanueva
Authors: Ezker Calvo Alicia
Published: April 2021

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On two-frequency quasi-periodic perturbations of systems close to two-dimensional Hamiltonian ones with a double limit cycle
Authors: Kostromina O.S.
Published: April 2021

The problem of the effect of two-frequency quasi-periodic perturbations on systems close to arbitrary nonlinear two-dimensional Hamiltonian ones is studied in the case when the corresponding perturbed autonomous systems have a double limit cycle. Its solution is important both for the theory of synchronization of nonlinear oscillations and for the theory of bifurcations of dynamical systems. In the case of commensurability of the natural frequency of the unperturbed system with frequencies of quasi-periodic perturbation, resonance occurs. Averaged systems are derived that make it possible to ascertain the structure of the resonance zone, that is, to describe the behavior of solutions in the neighborhood of individual resonance levels. The study of these systems allows determining possible bifurcations arising when the resonance level deviates from the level of the unperturbed system, which generates a double limit cycle in a perturbed autonomous system. The theoretical results obtained are applied in the study of a two-frequency quasi-periodic perturbed pendulum-type equation and are illustrated by numerical computations.
Mediation analysis for binary random variables : parametric decomposition of the total effect
Authors:   , Raggi Martina
Published: April 2021

This thesis is centered on the evaluation of direct and indirect effects via mediation analysis. A researcher is usually interested in assessing to what extent an exposure variable affects an outcome. However, identifying the overall effect does not answer questions concerning how and why such an effect arises. Single mediation analysis decomposes the overall effect of the exposure on the outcome into an indirect and a direct effect. The former refers to the to the effect of the exposure on the outcome due to a third variable, the mediator, which is supposed to fall in the pathway. The latter effect is the effect of the exposure on the outcome after keeping the mediator to whatever value might be of interest. Specifically, we derived novel exact parametric decompositions of the total effect into direct and indirect effect for binary random variables, both in the counterfactual and path-analysis frameworks. In the single mediation context, we derive parametric expressions of the counterfactual entities and their relationships with the associational definitions coming from the path analysis context. We apply these methodological results on a dataset coming from a randomly allocated microcredit program in Bosnia-Herzegovina to evaluate the effect on client’s bankability. We re-analyse the data, in order to build a mediation scheme that allows a better understanding of the main effect of the study, by assuming business ownership as a possible mediator. We also implement a simulation study to compare the proposed estimator to several competing ones. When multiple mediators are involved, we found alternative definitions for the decomposition of the total effect. These new definitions are more appropriate for variables modelled as a recursive system of univariate logistic regressions. Thus, by making use of graphical models, the overall effect was defined as the sum of the direct, indirect effects and a residual term that is null under certain hypotheses. In general, these expressions are written such that one can maintain the link between effects and their corresponding coefficients in logistic regression models assumed in the system.
Recent progress on antimonene: from theoretical calculation to epitaxial growth
Authors: Xue Cheng-Long , Li Shao-Chun
Published: April 2021

Monolayer antimony (antimonene) is an emerging 2D material that has recently attracted considerable attention due to its intriguing structure and fascinating electronic properties as theoretically predicted. In order to extensively explore this material in both fundamental research and potential applications, it is important to first prepare high-quality monolayer antimony. In this review, we focus on the theoretical calculations and experimental achievements for both α- and β- phases of antimonene, particularly through the use of molecular beam epitaxy. Moreover, we also provide insight for further exploring the appealing properties of antimonene and other materials with analogous structure.
Development of omnidirectional audible sound source using facing ultrasonic transducer arrays driven at different frequencies
Authors: Okamoto Kyoka , Okubo Kan
Published: April 2021

We present an audible sound source with omnidirectional patterns in the horizontal plane using facing ultrasonic transducer arrays driven at different frequencies. In this experiment, ultrasonic transducer arrays were placed face-to-face on a straight line. They radiated sound with different ultrasonic frequencies from each side. Through elementary examination, we realized directionality close to omnidirectional in the horizontal plane using ultrasonic transducer arrays arranged in a circular shape, which is rotationally symmetric in all degrees. In addition, using an acoustic camera, a sound source region was found to be generated between the arrays.
A tradución como ponte cultural ou como unha viaxe a través da mente dos lectores. A recepción das traducións ao inglés das obras de Manuel Rivas e Domingo Villar
Authors: Linares Laura
Published: April 2021

Nos últimos anos, os estudos de Tradución veñen vendo un aumento no interese sobre o lectorado de traducións, presente en estudos centrados na recepción de obras traducidas ben sexa a través dunha análise textual de recensións (Zhao 2009, Bielsa 2013, D’Egidio 2015, Saldanha 2018) ou de estudos realizados a través de entrevistas e grupos de lectura con lectores reais (Arnold 2016). En concreto, a recepción de obra traducida no mundo anglófono vén xerando un interese particular entre académicos que buscan comprender as expectativas e os patróns de consumo literario no contexto dunha cultura central e hexemónica. Este artigo explora a recepción das obras de Manuel Rivas e Domingo Villar no mundo anglófono e estuda como as recensións tanto profesionais (en prensa) como semiprofesionais (blogs) re-constrúena cultura galega segundo a noción de continuo homoxenización-heteroxenización-exotismo formulada por Saldanha (2018).
As coedicións de literatura infantil e xuvenil
Authors: Domínguez Pérez Mónica
Published: April 2021

Neste traballo, pártese da teoría dos polisistemas para analizar as coedicións de literatura infantil e xuvenil entre as literaturas do ámbito español: a castelá, a catalá, a vasca e a galega. A través das coedicións realizadas e do xeito en que foron producidas e recibidas, pódese observar a situación en que se encontraban os diferentes polisistemas implicados durante o período estudado: 1940-1980. Como conclusión xeral, pódese dicir que as institucións da literatura castelá apenas participan nas coedicións debido á posición central desta literatura no ámbito español. A literatura catalá, pola contra, lidera as relaciónsde coedición, reflectindo así non só un maior desenvolvemento desta literatura, mais tamén un interese por fomentar outros polisistemas periféricos do ámbito español. Pola súa parte, as literaturas galega e vasca encontrábanse nunha situación máis precaria, e xa que logo, a súa participación nas coedicións foi menos activa e máis inestable
The Virgin and the Gipsy. Descubrimento paio e lucidez vivaz que atravesa séculos
Authors: Domínguez-Araújo Lara
Published: April 2021

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Traducir a Fallada naturalmente
Authors: Buján Otero Patricia
Published: April 2021

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O tradutor holístico: a edición de Se isto é un home
Authors: Garrido Vilariño Xoán Manuel
Published: April 2021

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АНАЛІЗ ВПЛИВУ МІЖНАРОДНИХ ВІДНОСИН НА ЕКОНОМІЧНЕ ЗРОСТАННЯ ОКРЕМОЇ КРАЇНИ
Authors: Гудима Олег , Гудима Анастасія , Зінченко Катерина
Published: April 2021

У статті розглядається питання виявлення закономірностей між розвитком міжнародних відносин і економічним зростанням держав. Розглянуто три європейські країни, які входять в Європейський Союз та проаналізовано економічні показники: валовий внутрішній продукт в розрахунку на душу населення та індекс людського розвитку у порівнянні в період до вступу в Європейський Союз та станом на 2017 рік. За результатами проведеного аналізу статистичних даних, на основі теорії неолібералізму, було визначено що для суттєвого підвищення добробуту громадян окремо взятої країни необхідно суттєво підвищувати міжнародну активність. На основі виявлених закономірностей здійснено прогноз економічного зростання на п’ять років для України та Республіки Молдова при покращенні міжнародних відносин.
Visualization and Reduction of Mutual Coupling Between Antennas Installed on a Platform
Authors: Lundgren Johan , Malmström Johan , Hannula Jari-Matti , Jonsson Lars
Published: April 2021

Mutual coupling, or equivalently, the isolation between antennas, is a key parameter in antenna system design. In this work, the previously defined impedance density is generalized, and it is demonstrated how it can be used to obtain spatial information about the mutual coupling. The generalized impedance density is a real-valued scalar and it can be visualized as a three-dimensional density in space. It is shown that there is a strong connection between regions with a positive (negative) generalized impedance density and a decrease (increase) of the coupling when an absorber is placed in that region. This predictive ability is a useful feature, which is tested for three numerical cases. The results are robust to the shape of the platform, and it can be compared across frequencies. By placing absorbers based on the generalized impedance density, it is possible to reduce the required amount of absorbers needed to obtain a certain reduction in mutual coupling. The visualization results and predictions of absorber positions are compared with a Poynting vector based method. Placing absorbers based on the generalized impedance density had a larger impact on the mutual coupling, compared to the predictions with the Poynting vector based method in the investigated cases.
A Simple Chaotic Map Model for Fractal Traffic Flows in High-speed Computer Networks
Authors: Millán Ginno
Published: April 2021

An extension of the
models used to generate fractal traffic flows is presented by means of the
formulation of a model that considers the use of one-dimensional chaotic maps.
Based on the disaggregation of the temporal series generated by the model, a
valid explanation of behavior of the values of Hurst exponent is proposed and
the feasibility of their control from the parameters of the proposed model is shown.
Electrical Conductivity of PA6/Graphite and Graphite Nanoplatelets Composites using Two Processing Streams
Authors: Umar M. , Ofem M. I. , Anwar A. S. , Usman M. M.
Published: April 2021

The percolation threshold (PT) of any polymer/particulate carbon composite depends on the processing, the dispersed state of the filler, the matrix used and the morphology attained. Sonication technique was used to make PA6/G and PA6/GNP composites employing in situ polymerisation, after which their electrical conductivity behaviours were investigated. While overhead stirring and horn sonication were used to distribute and disperse the carbon fillers, the composites were made in 2 streams 40/10 and 20/20. The 40/10 stream implies that while dispersing the carbon fillers in PA6 monomer, 40% amplitude of sonication was applied for 10 minutes whereas the 20/20 stream implies 20% amplitude of sonication for 20 minutes. In both streams, the dispersing strain imparted on the monomer/carbon mixture was 400 in magnitude. Purely ohmic electrical conductivity behaviour was attained at 9.75 G wt. % for IG 40/10 system. For composites in the IG 20/20 system, same was attained at 10.00 G wt. %. Electrical conductivity sufficient for electrostatic discharge applications was achieved above 15 G wt. % in the IG 40/10 system. Using the power law percolation theory, percolation threshold was attained at 9.7 G wt. % loading in IG 40/10 system, while same was attained at 7.6 G wt. % loading in IG 20/20 system. For the GNP based systems, percolation threshold occurred at 5.2 GNP wt. % in the INP 40/10 system whereas same occurred at 7.4 GNP wt. % in the IG 20/20 system.
Еstimation of the complication rate and conformation for the case using orthopedic structures
Authors:   Tyumen State Medical University, Tyumen, Semenova M. V. , Nagaeva M. O. ,   Tyumen State Medical University, Tyumen, Semenova A. I. ,   Tyumen State Medical University, Tyumen, Diev M. S. ,   Tyumen State Medical University, Tyumen, Dzheiranashvili I. H. ,   Tyumen State Medical University, Tyumen
Published: April 2021

Aim. Analyze the frequency and structure of complications for the case using various types of orthopedic structures, which were identified by dentists in Tyumen. Materials and methods. According to the developed questionnaire, a survey was conducted of 100 dentists of various profiles with experience from 3 to 35 years, practicing on the basis of public and private clinics in Tyumen. Results. Based on the results of the questionnaire, materials and orthopedic structures were identified, which, according to doctors, cause various complications. It was revealed that the most common complications are complete removable, bridges (31%), partially removable prostheses (24.3%) and stamped-brazed prostheses (21.1%). Among structural materials, the most common complications are caused by structures made of acrylic plastic (35.1%), composite materials (22.2%). Complications revealed most often for the case using orthopedic structures: mechanical trauma (28%), allergic stomatitis (14.5%). Conclusion. Despite the improvement of construction materials and manufacturing processes for orthopedic structures, complications are common.
Forensic evaluation of age by X-ray morphometric features of the arytenoid cartilage of the human laryngeal complex
Authors:   Russian Center for Forensic Medical Examination, Moscow, Zvyagin V. N. , Galitskaya O. I. ,   Russian Center for Forensic Medical Examination, Moscow, Kalimullin R. R. ,   Regional Bureau of Forensic Medical Examination, Tyumen
Published: April 2021

The aim of the study was to develop a method for age evaluation based on the mineralization signs of the larynx arytenoid cartilage (AC) during the destroyed human corpse expertise. X-ray images of isolated AC preparations from both sexes (male – 264, female – 106) aged from 19 to 91 years were studied. Morphometry was conducted on: the area (in mm2) and the degree (%) of mineralization of both AC separately and united, a total of 6 features. Results. There is no correlation between the signs of AC mineralization and the length of the human body (r = 0.01-0.201). The correlation of these signs with age is high in men, (r = 0.741-0.781), and moderate in women (r = 0.470-0.508). There is a pronounced correlation between all age-dependent signs of AC (r = 0.948-0.985). According to the discriminant analysis results, the correct classification of the age groups 19-44 and 45-91 years is 82.9% in men, 77.03% in women. Practically reliable and probable diagnostics of men age is possible in 32.58 and 33.33%, of women age – in 5.41 and 37.84% of cases. According to the regression analysis, the age diagnostics in the range from 19 to 91 years in men is possible with an accuracy of ± 10.02 years (R = 0.799; R2 = 0.635), in women – ± 18.864 years (R = 0.506; R2 = –0.249). Forensic determination of the women age by regression models is excluded.
El arte es el espíritu de las cosas que se construyen
Authors: Gutiérrez Ernesto
Published: April 2021

En este artículo me propongo pensar el sentido del arte en la educación o el sentido de su enseñanza en nuestro sistema educativo. Son afirmaciones que me han permitido buscar la impronta del espíritu en lo que construyo, mi acción como docente y también como buscador (a veces como investigador, pero más en su etimología, el que va tras las huellas, que para los Yoruba es el que busca o ẹrọ wiwa).
University employees’ organizational abilities formation on the digital competencies basis: ensuring external and internal security
Authors: Kuznetsova Elena , Podoliak Olga
Published: April 2021

Within the resource approach framework, the organizational abilities specifics formation based on the modern digital competencies and organizational abilities formation are considered. The investigation purpose is to track the ensuring competitiveness and economic security above-mentioned elements formation using the example of a higher educational institution. The article is useful for business structures responsible for the formation of their organizational abilities on the personnel competencies basis.
CLINICAL FEATURES OF GASTROINTESTINAL ULCERATIVE BLEEDING IN ELDERLY PATIENTS COMPLICATED BY CARDIO-VASCULAR PATHOLOGY
Authors: Trofimov Mykola V. , Kryshen Valerii P. , Kudryavtseva Valentyna Y. , Chukhriienko Alla V. , Lyashchenko Pavlo V. , Gaponov Ivan V.
Published: April 2021

The aim: To determine clinical and endoscopical features of gastroduodenal hemorrhages in elderly patients with concomitant cardio-vascular pathology in a way by studying,
main indicators of the immune system for drawing up further tactics.
Material and methods: The study included 609 patients with ulcerative gastroduodenal bleeding, complicated by cardio-vascular system pathology in 2017-2019 years. The
observed patients were distributed into the groups: I – patients, who received treatment according to the standard system of cardiovascular pathology treatment (n=541),
II – “double” therapy (n=68). Control group consists of 20 relatively healthy patients were similar to the research group.
Results: Blood lost of a big amount and massive blood lost were noticed in 113 (18.56%±1.58) and 121 (19.87%±1.62) patients respectively. Active bleeding (F I) was revealed
in 38 patients (6.24%±0.98), a high risk of hemorrhage relapse was determined in 486 patients (79.80%±1.63). Signs of recent hemorrhage were absent in 85 patients
(13.96%±1.40). A high level of pro-inflammatory cytokines IL-6, TNF-α and a low activity of the anti-inflammatory mediator IL-10 define the process activity, their long-term
circulation in patients with ulcerative hemorrhages of the gastro-intestinal tract are associated with unfavorable prognosis. In 5 cases conditionally-radical surgical interventions
were performed. Palliative surgery – 3 patients (р>0.05).
Conclusions: The patients of second group (“double therapy”) with big and massive blood loss was 2.7 times higher than similar indices in patients of the first group (standard
therapy). The patients who received “double therapy” had 3.3 times more active hemorrhage percentage than the patients who received standard therapy (р<0.05).
LIFE QUALITY OF EMPLOYEES OF THE NORTH-EASTERN FEDERAL UNIVERSITY (YAKUTSK)
Authors: Stepanova Galina K. , Ustinova Maria V. , Nikolaeva Irina V.
Published: April 2021

The aim of the study evaluate the quality of life of employees of the North Eastern Federal University.
Materials and methods: The respondents to the WHO QoL 100 questionnaire were 37 teachers and 32 support staff with an average age of 44 years.
Results and conclusions: There is a higher correlation between assessments of overall satisfaction with the quality of life and individual areas in the group of surveyed teachers
compared to the group of support staff. Comparison of the parameters of the QOL areas of teachers of NEFU with the data of similar surveys of universities in Central Russia revealed
a higher assessment of such areas as the “environment”, the “physical” sphere among the Yakutia’s. These results indicate the adaptability of NEFU employees to environmental
conditions. Also, among the respondents of the Yakutia’s, there was revealed a great significance for the QOL of such a subsphere as support for relatives, friends and colleagues.
«OBESITY PARADOX» IN COMORBID STABLE ISCHEMIC HEART DISEASE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
Authors: Nemish Iryna L. , Stupnytska Ganna Ya. , Fediv Oleksandr I.
Published: April 2021

The aim: Was to find the possible relationship between spirometry tests, the BODE index (body mass index (BMI), airflow obstruction, dyspnea, and exercise tolerance) with
bioimpedance parameters in overweight and class I obese patients.
Materials and methods: 47 patients with stable ischemic heart disease (IHD) (I-II functional class), chronic obstructive pulmonary disease (COPD) (GOLD II, III, IV; groups B,
C, D) were divided into 3 groups: G1: 15 normal-weight patients, G2: 15 overweight subjects, and G3: 17 class I obese patients. Spirometry tests, bioimpedance parameters,
6MWT (6-minute walk test) were measured.
Results: FEV1 was significantly higher in overweight (p = 0.033) and class I obese (p = 0.049) subjects, the BODE index was lower in overweight (p = 0.033) and class I obese
(p = 0.037) patients, compared with normal-weight subjects. The statistically significant positive relationship was between BMI and FEV1 and the negative correlation was
between BMI and the BODE index in all groups of patients (p < 0.05).
Conclusions: In our study, we found better FEV1, 6MWT, the BODE index, the statistically significant association between FEV1 and the BODE index with BMI in overweight and
class I obese patients. That’s why we can suppose the presence of the “obesity paradox” in comorbid overweight or class I obese stable IHD, COPD patients.
THE ROLE OF THE KIDNEYS IN THE REGULATION OF THE ACID – BASE BALANCE OF THE BLOOD IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: Veremiienko Oksana V. , Ospanova Tatyana S. , Semydotska Zhanna D.
Published: April 2021

The aim: To study the regulation of acid-base balance and blood acid – renal excretory function in patients with COPD.
Materials and methods: We examined 82 people, suggests that even during the most severe stages of COPD. Group 1 included 56 patients with COPD, group C. The average
age was 60.54 + 2.04 years old, including 24 men and 32 women. The second group included 16 patients with COPD, group B, whose average age was 55.37 + 3.21 years old,
including 7 men and 9 women. The third group included 10 healthy individuals, with an average age of 34.30 + 2.21 years, including 6 men and 4 women. Respiration function
was evaluated on the basis of the forced expiratory curve recorded on a Spirolab II MIR S / N computer spirograph. The following indicators were evaluated: forced vital capacity
(FVC), forced expiratory volume (FEV1) and FEV1 / FVC ratio.
Results: For all patients with COPD there is a characteristic presence of acidosis (pH in patients with COPD group B – 7,34 ± 0,01, in patients with COPD group C – 7,31 ± 0,07).
For patients with COPD group C there are pronounced respiratory disorders (pCO2 – 48,25 + 1,14 mm Hg, p02 – 28.07 +1.37 mm Hg). For patients with COPD group B characteristic
metabolic disorders (BE--3,71 + 0,57), which increase as the disease progresses. For patients with COPD group C this figure is equal to 7.62 + 0.49. Thus, the analysis of indicators
indicates the presence for all patients of mixed (respiratory and metabolic) acidosis, which increases as the chronic obstructive pulmonary disease progresses.
Conclusions: There is activation of acid – renal excretory function and the inclusion of renal mechanisms in the regulation of acid-base balance.
HEALTH DYNAMICS OF THE MEDICAL UNIVERSITY STUDENTS DURING SPORTS ACTIVITIES
Authors: Melnychuk Iryna M. , Yastremska Svitlana O. , Popovych Dariya V. , Humeniuk Vasyl V. , Yefremova Oksana V. , Novakova Liubov V. , Shukatka Oksana V.
Published: April 2021

The aim: Is to investigate the dynamics of the morphofunctional development and physical health of students who were engaged in strength sports while studying at university.
Materials and methods: The study involved 360 male students of different faculties between the ages of 17 and 20. Two groups of students were formed: experimental and
control groups. The EG students (n=40) were engaged in strength sports (powerlifting, athletics, Crossfit); the CG students (n=320) were training according to the current
program of physical education. The study of the morphofunctional development of students was carried out taking account of the indicators of body length, body weight,
handgrip test, heart rate, blood pressure, and vital capacity. The level of students’ health was examined according to the methodology of the assessment of the physical health
level by G. L. Apanasenko.
Results: It was established that strength sports at university affect physical development, functional abilities of the major systems of an organism, and the health state of
future doctors in a more efficient way than the current program of physical education. It was found that the influence on the indicators of handgrip test, vital capacity, and
heart rate of the EG students was the most prominent positive effect of sports. The evaluation of the calculated indexes (power index, life index) and the level of physical health
confirmed this trend.
Conclusions: The conducted research asserts the necessity of introducing the sports-oriented form of the physical training organization at the medical higher education
institutions of Ukraine to strengthen the students’ health and to maintain the efficiency of the future doctors’ professional activity.
ACTIVITY OF SUPEROXIDE DISMUTASE AND CATALASE IN THE GASTRIC MUCOSA OF RATS UNDER THE PROLONGED ADMINISTRATION OF OMEPRAZOL AND COMBINATION OF OMEPRAZOLE AND MULTIPROBIOTICS
Authors: Pylypenko Serhii V. , Koval Andrii A. , Makarchuk Viktoria V.
Published: April 2021

The aim: Of the study was to study the activity of superoxide dismutase and catalase in the gastric mucosa of rats under long-term administration of omeprazole and combined
administration of omeprazole with Symbiter and Apibact multiprobiotics.
Materials and methods: The study was carried out on 40 white non-linear male rats with an initial weight of 160-180 g. All animals were divided into 4 groups. Group I was the
control. Group II was administered omeprazole once a day within the period of 28 days. Group III was administered a combination of omeprazole and Symbiter® multiprobiotic.
Group IV was administered a combination of omeprazole and Apibact® multiprobiotic.
The activity of superoxide dismutase in cells was determined by Chevars et al. . The catalase activity in cells was determined by Korolyuk et al. . Statistical processing of the
results was performed using the “Statistica 7.0” software.
Results: The activity of SOD and catalase in the gastric mucosa of rats after 28 days of omeprazole administration increased compared to the control. Probiotics reduced the
activity of SOD compared to the group of rats where omeprazole only was administered. The catalase activity in the gastric mucosa of rats which were jointly administered
omeprazole and multiprobiotics for 28 days did not statistically significantly differ from the similar index in the control group.
Conclusions: Prolonged gastric juice hypochlorhydria led to depletion of antioxidant protection enzymes. Multiprobiotics reduced the manifestation of the inflammatory
process in the gastric mucosa.
OVERVIEW OF WELLNESS METHODS FOR PEOPLE PRACTICING SPORTS
Authors: Laskowska Justyna , Hadław-Klimaszewska Olga , Jankowska Agnieszka , Zdziechowski Adam , Woldańska-Okońska Marta
Published: April 2021

The term “wellness” embraces a wide spectrum of methods that impact the human body by restoring its capabilities and functions, which were previously depleted as a result of increased physical and mental activities such, i.e. sport. Judging by the number of amateur, semi-professional, and professional sporting events at local and national levels, societies consider sports a major part of their everyday lives. A growing percentage of the population is exposing their bodies to various strains, which may result in fatigue, overtraining and injuries, and so the market demand for recovery-related services is on the rise. Therefore, this paper is an overview of the most important and the latest wellness systems and methods applied in today’s sport. They divide into three areas: pedagogical, psychological and medical-biological. Among the most popular treatments are: light radiation with infrared rays, cryotherapy, electrotherapy, magnetotherapy, ultrasound and laser therapy, as well as a sauna, paraffin compress, mud compress and brine baths. In a broader context, the paper also acknowledges the growing demand for better body recovery methods and the latest developments in the field of sport physiotherapy.
ECHOCARDIOGRAPHIC PREDICTORS OF THE EARLY POSTOPERATIVE PERIOD IN PATIENTS AFTER CORONARY ARTERY BYPASS GRAFT SURGERY
Authors: Moldotashev Ishenbai K. , Osmonov Damir A. , Kudaibergenova Nazira T. , Nazarov Asan K. , Unal Mustafa , Sorokin Aleksandr A.
Published: April 2021

The aim: The purpose of the present research was to study the results of coronary artery bypass graft (CABG) surgery depending on the degree of left ventricular ejection fraction (LVEF) reduction with the aim to identify additional echocardiographic predictors of the early postoperative period. Materials and methods: Were fixed, the results of CABG in 97 patients operated on in the “Bikard” private clinic from March 2016 to December 2018 were the material of the research. All patients underwent CABG surgery under cardiopulmonary bypass and cardioplegia, and in the preoperative period underwent echocardiographic examination according to the standard technique on the Vivid 7 machine. Patients, in dependent of the LVEF, were divided into 3 groups: group 1 35 people (LVEF < 40%), group 2 32 people ( 40% < LVEF < 50%), group 3 30 people (LVEF > 50%). Results: Our studies showed that the most important echocardiographic predictors of a complicated development of the disease in the early postoperative period, in addition to LVEF of the heart, can be the size of the left ventricle and left atrial, the presence and severity of mitral regurgitation and diastolic dysfunction of the left ventricle of the heart. Conclusions: Comprehensive measurement of these echocardiographic parameters will allow more accurately predict the results of coronary artery bypass grafting in the early postoperative period.
CLINICAL AND CYTOLOGICAL CHARACTERISTICS OF THE GUMS IN CHILDREN OF PRIMARY SCHOOL AGE WITH NORMAL BODY WEIGHT AND OVERWEIGHT
Authors: Onyschenko Anastasiia V. , Sheshukova Olga V. , Yeroshenko Halyna A.
Published: April 2021

The aim of the research was to study the cellular composition of the gums in children of primary school age with normal body weight and overweight for further use of this
data in the early diagnostics of periodontal diseases.
Materials and methods: We examined 81 children aged from 6 to 12 years. Cytological examination of gingival cytograms was performed in all examined children.
Results: Based on the analysis of the quantitative content of epithelial cells in children with normal body weight, their ratio was established, which is determined by the
percentage of 0: 6: 94 (parabasal, intermediate, superficial). The obtained data completely coincide with the percentage of the differentiated ratio of epitheliocytes of multilayered squamous epithelium in children with normal body weight with inflammation and without it in the periodontal tissues. Our cytological examinations of gingival scrape smears in overweight children in contrast to the results of the study of epithelial scrape smears in children with normal body weight have some differences. Thus, in the process of calculation, the degree of differentiation of various epitheliocytes determines their percentage as follows – 3: 7: 90 (parabasal, intermediate, superficial) for children with gingivitis, and 2: 5: 93 (parabasal, intermediate, superficial) for children without inflammation in the periodontal tissues.
Conclusions: The obtained results allowed us to conclude that in overweight children, in contrast to children with normal body weight, the number of parabasal cells decreases, and the number of superficial and intermediate cells increases.
NUTRITION PECULIARITIES OF UKRAINIAN ADOLESCENTS WITH METABOLIC SYNDROME
Authors: Strashok Larisa A. , Buznytska Olena V. , Meshkova Olena M.
Published: April 2021

The aim: To study the dietary peculiarities of Ukrainian adolescents with obesity and to identify the eating disorders on the background of metabolic syndrome.
Materials and methods: A survey on the nutrition of Ukrainian adolescents was conducted at O. Yaremenko Ukrainian Institute for Social Research within the framework of the international project Health and Behavioral Orientations of Student Youth (HBSC), 2018. As a result, a sample of 200 adolescents with obesity (age 14-18 years: 100 boys and 100 girls) was formed, with the following examination by the Institute of Children and Adolescents Health Care of the National Academy of Medical Sciences of Ukraine.
Results: A survey conducted revealed the problem of irrational and unbalanced diet in Ukrainian adolescents. Thus, irregular and unbalanced diet naturally causes digestive
disorders and contributes to the formation of comorbid pathologies such as obesity and metabolic syndrome. The general analysis of the DEBQ survey results revealed that patients with metabolic syndrome were twice as likely to have abnormalities in eating behavior (71.8 ± 3.7)% than in patients without them (39.4 ± 4.1)%, (φ < 0.05). Adolescents with obesity experienced significant zinc and magnesium deficiency in the body (φ < 0.05).
Conclusions: Modification of eating behaviour through healthy balanced nutrition and psychological support is one of the most important tasks in the treatment of patients
with obesity and metabolic syndrome.
RATIO OF MAIN PHYLOTYPES OF GUT MICROBIOTA IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE DEPENDING ON THE BODY MASS INDEX
Authors: Fadieienko Galyna D. , Chereliuk Nataliia I. , Galchinskaya Valentina Yu.
Published: April 2021

The aim: To analyze the status of Gut microbiota (GM) at the level of the main phylotypes in patients with NAFLD, depending on the body mass index (BMI) and gender in comparison with a group of practically healthy individuals.
Materials and methods: The study involved 120 patients with NAFLD, who were divided into two groups depending on BMI and the control group containing 20 practically
healthy individuals.
Results: In patients with NAFLD with comorbid obesity, a statistically significant increase in the relative amount of Firmicutes (52.12 [42.38; 67.39]%) and Firmicutes/Bacteroidetes
ratio (3.75 [1.7; 9.5]) against the background of a significant decrease in the amount of Bacteroidetes (13.41 [7.45; 26.07]%); in NAFLD patients with overweight, the relative
amount of Firmicutes was 49.39 [37.47; 62.73]%, Firmicutes / Bacteroidetes ratio was 1.98 [1.15; 5.92], and the relative amount of Bacteroidetes was 23.69 [12.11; 36.16]%.
In the control group, the distribution of the basic GM phylotypes was significantly different; the relative amount of Bacteroidetes was almost the same as of Firmicutes — 34.65 [24.58; 43.53]% and 29.97 [22.52; 41.75]% respectively, and the Firmicutes/Bacteroidetes ratio was 0.64 [0.52; 1.47].
Conclusions: The most statistically significant changes in the composition of IM occur due to the increase in the relative amount of Firmicutes and the ratio of Firmicutes/
Bacteroidetes against the background of a decrease in the relative amount of Bacteroidetes. These changes were directly proportional to the increase in BMI, but had no gender
features.
DIAGNOSTIC AND PREDICTIVE VALUE OF RIGHT HEART CATHETERIZATION-DERIVED MEASUREMENTS IN PULMONARY HYPERTENSION
Authors: Barańska-Pawełczak Karolina , Wojciechowska Celina , Jacheć Wojciech
Published: April 2021

Right heart catheterization is a unique tool not only in the diagnosis but also in the management of patients with a wide range of cardiovascular diseases. The technique dates back to the 18th century, but the biggest advances were made in the 20th century. This review focuses on pulmonary hypertension for which right heart catheterization remains the diagnostic gold standard. Right heart catheterization-derived parameters help classify pulmonary hypertension into several subgroups, assess risk of adverse events or mortality and make therapeutic decisions. According to the European Society of Cardiology guidelines pulmonary hypertension (PH) is defined as an increase in mean pulmonary artery pressure (PAPm) > 25 mmHg, whereas a distinction between pre- and post-capillary PH is made based on levels of pulmonary artery wedge pressure (PAWP). Moreover, right atrial pressure (RAP), cardiac index (CI) and mixed venous oxygen saturation (SvO2) are the only parameters recommended to assess prognosis and only in patients with pulmonary arterial hypertension (PAH). Patients with RAP > 14 mmHg, CI < 2.0 l/min/m2 and SvO2 < 60% are at high (> 10%) risk of death within the next year. The purpose of this paper is to show that RHC-derived parameters can be used on a considerably larger scale than currently recommended. Several prognostic parameters, with specific thresholds have been identified for each subtype of pulmonary hypertension and can be helpful in everyday practice for treatment of PH.