bluuebunny/crossref_metadata_2025 huggingface dataset:
A Practical Design Guide for Unbonded Jointed Plain Concrete Roads over Deteriorated HMA Roads: Realistic Traffic Loading
Authors: Baş Fatih İrfan , Bayrak Osman Ünsal , Bayata Halim Ferit
Published: November 2022

This study aimed to determine the material properties and the thickness of the layers of an unbonded jointed plain concrete pavement design over a deteriorated flexible pavement that lost its service capability. Maximum principal stresses occurring under the concrete pavement should not exceed the modulus of rupture of the concrete. Three-dimensional finite element analyses using ANSYS (Release 18.1 SAS IP, Inc.) software were carried out with the Taguchi method. The most reliable solution for the pavement design was investigated with whole configuration axle loading that reflects the realistic traffic situation. The stress values under the concrete slab due to the positive temperature gradient neglected in the American Association of State Highway and Transportation Officials (AASHTO) method were also investigated. The concrete slabs are exposed to these stresses for longer than the axle loads. Temperature distributions throughout the thickness of the concrete slab were calculated with the bilinear formulas suggested in the study. Axle loadings were applied on both the pavement edge and corner to reflect the most critical loading condition in the pavement design. The critical axle type was found to be 1.2. It was observed that a 0.15 m concrete thickness was appropriate for the concrete class, joint spacing and hot mix asphalt (HMA) elasticity modulus levels used for the 1.22, 1.122, and 1.2 + 111 axle types, but it was not appropriate for the 1.2 axle types. The slab thicknesses calculated with the AASHTO method, and the finite element method were found to be close to each other. It was determined that the concrete thickness significantly affected the maximum principal stress, with a performance statistic (S/N) value of 1692 for the 1.2 axle type. This was followed by the modulus of elasticity of the concrete with an S/N value of 0.356, the modulus of elasticity of the existing flexible pavement with an S/N value of 0.244, and the concrete joint spacing with an S/N value of 0.105. A practical design guide was recommended to extend the service life of a highly deteriorated flexible pavement with the construction of unbonded jointed plain concrete.
Electro-Optical Characteristics of Solution-Derived Zinc Oxide Film According to Number of Rubbing Iterations for Liquid Crystal Alignment
Authors: Park Hong-Gyu , Kim Jin-Ah , Ko Bong-Jin
Published: November 2022

Zinc oxide (ZnO) films reportedly exhibit a rubbing effect for liquid crystal (LC) alignment. In this study, we investigated the LC alignment characteristics of solution-derived ZnO films according to the number of rubbing iterations. Uniform and homogeneous LC alignments were achieved on the rubbed ZnO films, regardless of the number of rubbing iterations. As the number of rubbing iterations increased, the surface energies of the rubbed ZnO films were similar to 42.20 mJ/m2, but the polar energy increased from 4.288 mJ/m2 to 6.470 mJ/m2. Additionally, the electro-optical characteristics of the twisted-nematic (TN) LC cells fabricated by rubbed ZnO films showed the best performance when the number of rubbing iterations was at five. By confirming that the ZnO film with improved physical, chemical, and electro-optical characteristics compared to the polyimide film achieved a perfect LC alignment through the conventional rubbing process, it indicates that the ZnO film can be an excellent substitute for the LC alignment film. In addition, it is expected that it can be applied to an LC-based virtual reality (VR)/augmented reality (AR) display system that requires a very fast response time through the excellent EO characteristics of the TN LC cell of the solution-derived ZnO film through the rubbing process.
Inventory of the Ichthyofauna of the Mpem and Djim National Park (Center, Cameroon) Provides Baseline Data for a Conservation Project
Authors: Njom Samuel D. , Bitja Nyom Arnold R. , Hassan Bassirou , Bissek Jean P. , Bêche Leah , Pariselle Antoine , Bilong Bilong Charles F.
Published: November 2022

The intense anthropization of the Sanaga basin requires an acceleration of research on biodiversity and the conservation of its aquatic resources. In this framework, the ichthyofauna of the Mpem and Djim National Park (MpDNP) has been inventoried for the first time. The fish were sampled from 2017 to 2021 using diverse experimental fishing gears. A total of 79 species classified into 39 genera, 14 families, and 8 orders have been identified in the MpDNP. This ichthyofauna represents 46.7% of the 169 freshwater fish species known in the Sanaga basin. It contains 15 (62.5%) of the 24 endemic species reported in this basin, among them two Endangered and three Vulnerable species known on the IUCN Red List. Furthermore, two non-indigenous species have been inventoried. Siluriformes (36%) and Characiformes (22%) are the most represented in the MpDNP. It is suggested that the issues for conservation in this park must be focused as a priority on 15 endemic species, which may be ranged into two national protection classes A (5) and B (10), then on those in class C, which will be identified posteriorly as supplementary priorities for the offset of the residual impacts of the Nachtigal upstream hydropower plant development.
Muscular Systems and Their Influence on Foot Arches and Toes Alignment—Towards the Proper Diagnosis and Treatment of Hallux Valgus
Authors: Dygut Jacek , Piwowar Monika
Published: November 2022

(1) Background: Static foot deformities, including hallux valgus, are common deformities. The subject under consideration is the role of extrinsic and intrinsic muscles working within muscular systems that shape the arches of the foot and the alignment of the toes. (2) Methods: Based on a literature review, the muscle systems were analyzed. The systems under consideration were as follows: “tendon stirrup” (system I); muscles complementary to the tendon stirrup (system II); “foot lever” (system III); muscles complementary to system III (system IV); “reins of hallux” (system V), a muscular system having distal inserts on the hallux. The shape of the foot arches was analyzed in this context. (3) Results: The correct arch architecture of the foot stabilized mainly by the extrinsic muscle systems determining the function of the intrinsic muscle systems of the foot is described. The proper function of muscular systems shaping the arches of the foot is a prerequisite for the proper function of muscles directly responsible for the alignment of the big toe (hallux) and other foot toes. (4) Conclusion: The action of muscles should be considered in groups (systems) because the action of the group of muscles results in the creation of a new quality of movement. The analysis of individual muscle-pulling forces, especially the moments of force in the weight-bearing foot, may lead to extremely incorrect conclusions. In pathological cases, the restoration of the correct arches of the foot guarantees the recovery of the correct function of the pulling forces of the foot muscles responsible for the physiological alignment of the hallux. This is especially important concerning conservative and surgical treatment of hallux valgus.
Teaching and Learning in Higher Education in Bangladesh during the COVID-19 Pandemic: Learning from the Challenges
Authors: Shohel M. Mahruf C. , Roy Goutam , Ashrafuzzaman Md. , Babu Rasel
Published: November 2022

The higher education sector globally has gone through a transition because of the coronavirus outbreak, and as a result, many traditional higher education institutions across the globe have been forced to go online to provide education and arrange assessments so that their students could continue their education and complete their courses. Unlike developed countries, at the beginning of the lockdown, most of the higher education institutions in Bangladesh shut down their operations, and a few universities started moving toward online distance teaching and learning activities. Based on an empirical study, this article discusses the challenges of teaching and learning in higher education in Bangladesh during the COVID-19 lockdown. It also identifies good practices to overcome those challenges. An online survey was conducted to collect data from university teachers throughout the country. Findings from this study show that it was a great challenge for most universities to adopt online teaching and learning models at the beginning of the pandemic. Many factors, such as preparedness, limited resources including financial means, low digital literacy, internet connectivity and suitable physical and virtual infrastructure affected this transition. However, the findings also show that the COVID-19 pandemic created new opportunities for educators and practitioners to explore various professional development activities by trying out different digital pedagogies through practice and reflection. This article also highlights the immediate effect and long-term impact on teaching and learning regarding preparedness for future approaches to education in emergencies.
Exploring the BME Attainment Gap in a Russell Group University: A Mixed Methods Case-Study
Authors: Quyoum Aunam , Powell Stephanie , Clark Tom
Published: November 2022

Presenting the results from a mixed methods case-study, this paper draws together insight from the fields of ‘BME attainment’ and ‘student transition’ to explore how differential levels of degree attainment might be experienced within the context of a higher tariff university in England. Across a five-year period (2010/11–2014/2015) it compares the levels of degree attainment between UK-domiciled White and Black and Minority Ethnic (BME) students in relation to prior attainment, qualification type, and socioeconomic group (POLAR 3). A range of qualitative data then outlines a series of dynamic factors that can, when compounded, serve to constrain BME students’ capability to negotiate their way through very particular university landscapes. These include: academic expectation and preparedness; the pedagogic terrain; pastoral engagement and sense of belonging finance; and, the lived experience of diversity and ‘othering’. The paper argues that attainment gaps should not be viewed in terms of an individual deficit that needs to be ‘fixed’ or ‘filled’. Instead, greater attention needs to be directed toward enhancing the capacity of higher tariff universities to respond positively to the needs of a changing demographic.
Greener or Greyer? Exploring the Trends of Sealed and Permeable Spaces Availability in Italian Built-Up Areas during the Last Three Decades
Authors: di Cristofaro Marco , Di Pirro Elena , Ottaviano Marco , Marchetti Marco , Lasserre Bruno , Sallustio Lorenzo
Published: November 2022

Increasing the availability of greenspaces in built-up areas (GSB) is one of the main challenges to improving sustainability and livability in urban landscapes. Concurrently, the availability of brownfields and permeable spaces offers the chance to increase sustainability through the implementation of Nature-Based Solutions. This work aims to evaluate how land use/cover changes influenced the availability of permeable spaces in Italian built-up areas over the last three decades. These spaces were classified according to population density, vegetation type, and average size, to better characterize recent dynamics (2008–2016) and offer remarks and tips concerning ongoing soil sealing dynamics. According to the findings, despite an overall increase of 41.5% in built-up areas with respect to their 1990 extension, permeable spaces increased only by 25.2% during the same time-span, moving from 49.8% coverage in 1990 to 44.7% today, in relation to the whole national built-up area. Moreover, our in-depth analysis for the 2008–2016 period shows that forested spaces increased by 0.4%, while permeable unforested ones decreased by 0.7%, especially in thinly and intermediately populated areas. Overall, the scarcity of these spaces should be carefully considered when assigning residual vacant lots to new buildings and grey infrastructure, especially in densely populated areas. The proposed methodology provides reliable estimates and represents a starting point to develop advanced monitoring tools supporting sustainable urban policies.
Forest Damage by Extra-Tropical Cyclone Klaus-Modeling and Prediction
Authors: Pawlik Łukasz , Godziek Janusz , Zawolik Łukasz
Published: November 2022

Windstorms may have negative consequences on forest ecosystems, industries, and societies. Extreme events related to extra-tropical cyclonic systems remind us that better recognition and understanding of the factors driving forest damage are needed for more efficient risk management and planning. In the present study, we statistically modelled forest damage caused by the windstorm Klaus in south-west France. This event occurred on 24 January 2009 and caused severe damage to maritime pine (Pinus pinaster) forest stands. We aimed at isolating the best potential predictors that can help to build better predictive models of forest damage. We applied the random forest (RF) technique to find the best classifiers of the forest damage binary response variable. Five-fold spatial block cross-validation, repeated five times, and forward feature selection (FFS) were applied to the control for model over-fitting. In addition, variable importance (VI) and accumulated local effect (ALE) plots were used as model performance metrics. The best RF model was used for spatial prediction and forest damage probability mapping. The ROC AUC of the best RF model was 0.895 and 0.899 for the training and test set, respectively, while the accuracy of the RF model was 0.820 for the training and 0.837 for the test set. The FFS allowed us to isolate the most important predictors, which were the distance from the windstorm trajectory, soil sand fraction content, the MODIS normalized difference vegetation index (NDVI), and the wind exposure index (WEI). In general, their influence on the forest damage probability was positive for a wide range of the observed values. The area of applicability (AOA) confirmed that the RF model can be used to construct a probability map for almost the entire study area.
Removal of Zearalenone from Degummed Corn Oil by Hydrolase on a Batch-Refining Unit
Authors: Zhao Chenwei , Xie Pengkai , Jin Jun , Jin Qingzhe , Wang Xingguo
Published: November 2022

The removal of zearalenone (ZEN) from degummed corn oil (DCO) using hydrolase on a batch-refining unit was studied. According to single-factor and response surface experiments, the optimum technological conditions for reaching the maximum degradation rate were a temperature of 39.01 °C, a pH of 8.08, a time of 3.9 h, and an enzyme dosage of 44.7 mg/kg, whereby the rate of ZEN degradation can reach 94.66%. Different effects on the removal of ZEN were observed at different initial ZEN contents under the optimal technological conditions, of which the decrease was rapid for high ZEN content and slow for low ZEN content.
Framing of COVID-19 in Newspapers: A Perspective from the US-Mexico Border
Authors: Afrin Rifat , Harun Ahasan , Prybutok Gayle , Prybutok Victor
Published: November 2022

The degree to which the media report a health emergency affects the seriousness with which the people respond to combat the health crisis. Engagement from local newspapers in the US has received scant scrutiny, even though there is a sizable body of scholarship on the analysis of COVID-19 news. We fill this void by focusing on the Rio Grande Valley area of the US-Mexico border. To understand the differences, we compared such local news coverage with the coverage of a national news outlet. After collecting the relevant news articles, we used sentiment analysis, rapid automatic keyword extraction (RAKE), and co-occurrence network analysis to examine the main themes and sentiments of COVID-19 news articles. The RAKE identified that county-specific news or local regulations are more prevalent among the key terms in The Monitor which are absent in USA Today. The co-occurrence network shows the coverage of the disruption of sports season in USA Today which is not present in The Monitor. The sentiment analysis presents fear emotion is more dominant in USA Today, but trust emotion becomes more prevalent in The Monitor news coverage. These findings show us that, although the subject of the health emergency is the same, local and national newspapers describe it in different ways, and the sentiments they convey are also not the same.
Association of Digital Health Literacy with Future Anxiety as Mediated by Information Satisfaction and Fear of COVID-19: A Pathway Analysis among Taiwanese Students
Authors: Chen Sheng-Chih , Huy Le Duc , Lin Cheng-Yu , Lai Chih-Feng , Nguyen Nhi Thi Hong , Hoang Nhi Y. , Nguyen Thao T. P. , Dang Loan T. , Truong Nguyen L. T. , Phan Tan N. , Duong Tuyen Van
Published: November 2022

Digital Health Literacy (DHL) helps online users with navigating the infodemic and co-existing conspiracy beliefs to avoid mental distress and maintain well-being. We aimed to investigate the association between DHL and future anxiety (FA); and examine the potential mediation roles of information satisfaction and fear of COVID-19 (F-CoV). A web-based cross-sectional survey was carried out among 1631 Taiwanese university students aged 18 years and above from June 2021 to March 2022. Data collected were socio-demographic characteristics (sex, age, social status, university location), information satisfaction, F-CoV, DHL and FA (using Future Dark scale). The linear regression model was used to explore factors associated with FA. The pathway analysis was further used to evaluate the direct and indirect relationship between DHL and FA. A higher score of DHL (B = −0.21; 95% CI, −0.37, −0.06; p = 0.006), and information satisfaction (B = −0.16; 95% CI, −0.24, −0.08; p < 0.001) were associated with a lower FA score, whereas a higher F-CoV score was associated with a higher FA score (B = 0.43; 95% CI, 0.36, 0.50; p < 0.001). DHL showed the direct impact (B = −0.1; 95% CI, −0.17, −0.04; p = 0.002) and indirect impact on FA as mediated by information satisfaction (B = −0.04; 95% CI, −0.06, −0.01; p = 0.002) and F-CoV (B = −0.06, 95% CI, −0.08, −0.04; p < 0.001). Strategic approaches to promote DHL, information satisfaction, lower F-CoV are suggested to reduce FA among students.
Effects of Oxytetracycline/Lead Pollution Alone and in the Combined Form on Antibiotic Resistance Genes, Mobile Genetic Elements, and Microbial Communities in the Soil
Authors: Guo Tengfei , Li Zhaoyi , Shao Yanqiu , Fu Yanli , Zhang Weiyi , Shao Yingying , Zhu Ying
Published: November 2022

The application of livestock manure is the leading cause of antibiotic and heavy metal pollution in agricultural soil. However, the effects of oxytetracycline (OTC) and lead (Pb) pollution in the single or combined form on antibiotic resistance genes (ARGs) in the soil need to be further studied. This study was planned to investigate the effects of OTC and Pb application on ARGs, mobile genetic elements (MGEs), and bacterial abundance in the soil. The relative abundance of ARGs and MGEs increased by 0.31-fold and 0.03-fold after the addition of 80 mg kg−1 Pb to the soil, and by 0.49-fold and 0.03-fold after the addition of 160 mg kg−1 Pb. In addition, under the premise of the existence of OTC, the inhibitory effect of a low concentration of Pb on ARG is stronger than that of a high concentration of Pb, resulting in a lower abundance of ARGs. The abundance of ARGs and MGEs increased by 0.11-fold and 0.17-fold after the addition of OTC (30 mg kg−1) to the soil at a Pb concentration of 80 mg kg−1 and by 0.18-fold and 0.04-fold at a Pb concentration of 160 mg kg−1. The addition of OTC and Pb in the soil also decreased the many bacterial communities such as Bacteroidetes, Proteobacteria, Acidobacteria, and Firmicutes. Redundancy analysis (RDA) showed that organic matter content and pH were positively correlated with the abundance of ARGs and MGEs. At the same time, electrical conductivity (EC) had a negative correlation with the abundance of ARGs and MGEs in the soil. Intl1 was significantly associated with tetB, sul1, tetQ, sul2, and sul3. Network analysis illustrated that Actinobacteria, Bacteroidetes, and Proteobacteria were the main host bacteria causing changes in the abundance of ARGs and MGEs, and they were also predominant phylum in the culture environment. This conclusion can provide a reference for the related research of ARGs in soil.
The Mediating Effect of Empathy between Mindfulness and Self-Leadership in Female University Students: A Cross-Sectional Study
Authors: Lee Mikyoung , Jung Mijung
Published: November 2022

(1) Background: Acknowledging scant research on integrating mindfulness, empathy, and self-leadership among female university students, this study aimed to investigate the relationships among these three variables, as well as the mediating effect of empathy. (2) Methods: A cross-sectional design was employed with 127 female sophomores in a mindfulness-based liberal arts class at K Women’s University in South Korea. Participants completed a self-reported questionnaire measuring levels of mindfulness, empathy, and self-leadership. Data were analyzed with descriptive statistics and correlations between the variables using the SPSS 28 program. The Jamovi 2.2.5 program was used to analyze the mediating effect of empathy. (3) Results: The levels of mindfulness, empathy, and self-leadership were higher than in previous studies. Mindfulness was positively related to empathy (r = 0.407, p < 0.001) and self-leadership (r = 0.635, p < 0.001); empathy was also positively associated with self-leadership (r = 0.635, p < 0.001). Furthermore, empathy mediated the relationship between mindfulness and self-leadership (β = 0.187, p < 0.001). (4) Conclusions: The findings indicate that mindfulness is helpful in improving university students’ self-leadership by reinforcing their empathy, and that an integrated training program of mindfulness and empathy could produce positive effects on promoting self-leadership. The findings can be utilized as a basis for developing programs to improve mindfulness and empathy, eventually improving students’ self-leadership.
Factors Associated with Depression and Anxiety Symptoms among Migrant Population in Spain during the COVID-19 Pandemic
Authors: Bayes-Marin Ivet , Roura-Adserias Maria , Giné-Vázquez Iago , Villalobos Felipe , Franch-Roca Marta , Lloret-Pineda Amanda , Gabarrell-Pascuet Aina , He Yuelu , Hafi Rachid El , Butt Fajar Matloob Ahmed , Mellor-Marsá Blanca , Alós M. Carmen , Sainz-Elías Helena , Ayad-Ahmed Wala , Aparicio Lola , Cabeza Mercedes Espinal , Bobo Óscar Álvarez , López Yolanda Osorio , Haro Josep Maria , Cristóbal-Narváez Paula
Published: November 2022

Migrants are likely to experience mental health conditions, being one of the most vulnerable groups during the COVID-19 pandemic. The present study aims to: (1) estimate the prevalence of depressive and anxious symptoms and (2) examine the impact of risk and protective factors on this symptomatology. A sample of 129 migrants living in Spain during the COVID-19 pandemic completed an anonymous online survey, including information on sociodemographic and individual characteristics, migration, basic needs, social environment and perceived health domains. Multiple Poisson regression models analysed the effects of risk and protective factors on depression and anxiety symptoms. The prevalence of depressive and anxiety symptoms was 22.3% and 21.4%, respectively. Risk factors such as living in a rented house and previous mental health conditions were associated with higher depression symptoms, whereas unemployment was related to anxiety symptoms. Conversely, older age, better self-esteem, and higher levels of social support were associated with fewer depression symptoms. Older age and better quality of life were related to fewer anxiety symptoms. These findings addressing risk and protective factors (e.g., social support, self-esteem) help to design culturally effective programs, particularly in migrants with pre-existing mental health conditions, adjusting the organisation of mental healthcare services in difficult times in Spain.
Development and Validation of a Nomogram Based on Metabolic Risk Score for Assessing Lymphovascular Space Invasion in Patients with Endometrial Cancer
Authors: Wang Jingyuan , Li Xingchen , Yang Xiao , Wang Jianliu
Published: November 2022

Objective: This study assessed the predictive value of the metabolic risk score (MRS) for lymphovascular space invasion (LVSI) in endometrial cancer (EC) patients. Methods: We included 1076 patients who were diagnosed with EC between January 2006 and December 2020 in Peking University People’s Hospital. All patients were randomly divided into the training and validation cohorts in a ratio of 2:1. Data on clinicopathological indicators were collected. Univariable and multivariable logistic regression analysis was used to define candidate factors for LVSI. A backward stepwise selection was then used to select variables for inclusion in a nomogram. The performance of the nomogram was evaluated by discrimination, calibration, and clinical usefulness. Results: Independent predictors of LVSI included differentiation grades (G2: OR = 1.800, 95% CI: 1.050–3.070, p = 0.032) (G3: OR = 3.49, 95% CI: 1.870–6.520, p < 0.001), histology (OR = 2.723, 95% CI: 1.370–5.415, p = 0.004), MI (OR = 4.286, 95% CI: 2.663–6.896, p < 0.001), and MRS (OR = 1.124, 95% CI: 1.067–1.185, p < 0.001) in the training cohort. A nomogram was established to predict a patient’s probability of developing LVSI based on these factors. The ROC curve analysis showed that an MRS-based nomogram significantly improved the efficiency of diagnosing LVSI compared with the nomogram based on clinicopathological factors (p = 0.0376 and p = 0.0386 in the training and validation cohort, respectively). Subsequently, the calibration plot showed a favorable consistency in both groups. Moreover, we conducted a decision curve analysis, showing the great clinical benefit obtained from the application of our nomogram. However, our study faced several limitations. Further external validation and a larger sample size are needed in future studies. Conclusion: MRS-based nomograms are useful for predicting LVSI in patients with EC and may facilitate better clinical decision-making.
Measuring Water Quantity Used for Personal and Domestic Hygiene and Determinants of Water Use in a Low-Income Urban Community
Authors: Sultana Rebeca , Nahar Nazmun , Luby Stephen P. , Swarna Sayeda Tasnuva , Gurley Emily S. , Tamason Charlotte Crim , Khan Shifat , Rimi Nadia Ali , Kabir Humayun , Saifullah Md. Khaled , Howlader Sushil Ranjan , Jensen Peter Kjær Mackie
Published: November 2022

There is a paucity of recent research on direct water quantity measurement for personal and domestic hygiene. We aimed to measure the water quantity used for personal and domestic hygiene and to explore the reasons and determinants for variation of water usage. We conducted this study from September 2014 to June 2016 in a low-income urban community in Dhaka. In 12 households, the team conducted a day-long bimonthly ethnographic observation for one year to measure the volume of water used per activity per person. They conducted 28 in-depth interviews to explore the reasons for changes of water usage. Participants used a median of 75 L (61–100) of water per capita per day (LCPD) and of this 75 LCPD they used a median of 39 LCPD (26–58) for personal hygiene. Women used less water than men. Individual and social norms, beliefs, and weather determinants determined personal hygiene. Water availability determined domestic hygiene (e.g., washing dishes, toilets and bathrooms). This study helps to elucidate a range of determinants of water usage of the participants from the participants’ perspective. The quantity of water used for domestic and personal hygiene and its relationship to fecal-oral transmitted disease can be explored in future research.
Child Maltreatment and Intimate Partner Violence in Mental Health Settings
Authors: McTavish Jill R. , Chandra Prabha S. , Stewart Donna E. , Herrman Helen , MacMillan Harriet L.
Published: November 2022

Intimate partner violence (IPV) and child maltreatment (physical, emotional, sexual abuse, neglect, and children’s exposure to IPV) are two of the most common types of family violence; they are associated with a broad range of health consequences. We summarize evidence addressing the need for safe and culturally-informed clinical responses to child maltreatment and IPV, focusing on mental health settings. This considers clinical features of child maltreatment and IPV; applications of rights-based and trauma- and violence-informed care; how to ask about potential experiences of violence; safe responses to disclosures; assessment and interventions that include referral networks and resources developed in partnership with multidisciplinary and community actors; and the need for policy and practice frameworks, appropriate training and continuing professional development provisions and resources for mental health providers. Principles for a common approach to recognizing and safely responding to child maltreatment and IPV are discussed, recognizing the needs in well-resourced and scarce resource settings, and for marginalized groups in any setting.
Image-Based Approach to Intrusion Detection in Cyber-Physical Objects
Authors: Golubev Sergey , Novikova Evgenia , Fedorchenko Elena
Published: November 2022

Recently, approaches based on the transformation of tabular data into images have gained a lot of scientific attention. This is explained by the fact that convolutional neural networks (CNNs) have shown good results in computer vision and other image-based classification tasks. Transformation of features without spatial relations to images allows the application of deep neural networks to a wide range of analysis tasks. This paper analyzes existing approaches to feature transformation based on the conversion of the features of network traffic into images and discusses their advantages and disadvantages. The authors also propose an approach to the transformation of raw network packets into images and analyze its efficiency in the task of network attack detection in a cyber-physical object, including its robustness to novel and unseen attacks.
Temperature-Dependent Development Models Describing the Effects of Temperature on the Development of the Fall Armyworm Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae)
Authors: Malekera Matabaro Joseph , Acharya Rajendra , Mostafiz Md Munir , Hwang Hwal-Su , Bhusal Narayan , Lee Kyeong-Yeoll
Published: November 2022

The fall armyworm Spodoptera frugiperda (J.E. Smith) is an economically important pest that recently invaded Africa and Asia; however, information regarding its biological capacity to establish itself in newly invaded environments is largely unknown. We investigated the effects of temperature on the development and survival of the invaded populations of S. frugiperda and selected mathematical models to evaluate its development in a new environment. S. frugiperda exhibited optimum survival and growth at temperatures between 28 °C and 30 °C. The lower and upper thermal thresholds for the egg-to-adult life cycle were 13.51 °C and 34.13 °C, respectively. We compared seven mathematical models and found that the Shi model was the most suitable for describing the temperature-dependent development rate of S. frugiperda. Therefore, the Shi mathematical model may be used to predict both the occurrence of particular developmental stages and the geographic distribution to implement measures for the management of S. frugiperda in agricultural fields.
High-Intensity Interval Training (HIIT) on Biological and Body Composition Variables in Patients with Musculoskeletal Disorders: A Systematic Review and Meta-Analysis
Authors: Casaña José , Varangot-Reille Clovis , Calatayud Joaquín , Suso-Martí Luis , Sanchís-Sánchez Enrique , Aiguadé Ramón , López-Bueno Rubén , Gargallo Pedro , Cuenca-Martínez Ferran , Blanco-Díaz María
Published: November 2022

In order to assess the impact of high-intensity interval training (HIIT) on biological and body composition variables in patients with musculoskeletal disorders (MSKD), a systematic search on PubMed (Medline), CENTRAL, CINAHL, Web of Science, SPORTDiscus, and Scopus was conducted. Standardized mean differences (SMD) and 95% confidence intervals were calculated and pooled in a meta-analysis using the random-effects model. The effectiveness of HIIT on waist circumference, muscle mass, resting heart rate, resting systolic and diastolic blood pressure, C-reactive protein, body weight, and body fat were determined. GRADE, risk of bias 2, and PEDro scales were employed. HIIT compared to no intervention, minimal intervention, or usual care did not show significant results in its favor on any of the variables studied, except for the resting heart rate when compared with no intervention (SMD = −0.33; 95% CI: −0.63, −0.04; heterogeneity Q value: 0.14; p = 0.93; I2 = 0%). In addition, HIIT also does not seem to be more effective than moderate-intensity continuous training. Based on the results, it seems that HIIT has almost no significant effects on biological and body composition variables, except for resting heart rate, in patients with MSKD.
Esophageal Protection and Temperature Monitoring Using the Circa S-Cath™ Temperature Probe during Epicardial Radiofrequency Ablation of the Pulmonary Veins and Posterior Left Atrium
Authors: Kronenberger Rani , Parise Orlando , Van Loo Ines , Gelsomino Sandro , Welch Ashley , De Asmundis Carlo , La Meir Mark
Published: November 2022

Although epicardial bipolar radiofrequency ablation should diminish the risk of esophageal thermal injury in comparison to an endocardial ablation, cases of lethal atrio-esophageal fistula have been reported. To better understand this risk and to reduce the possibility of a thermal injury, we monitored the esophageal temperature with the Circa S-Cath™ temperature probe during and immediately after the ablation while implementing three procedural safety measures. Twenty patients (15 males; 63 ± 10 years) were prospectively enrolled (November 2019–February 2021). All patients underwent an epicardial ablation procedure, including an antral left and right pulmonary vein isolation with bidirectional bipolar clamping, and a roof and inferior line using unidirectional bipolar radiofrequency. Three procedural preventive mitigations were implemented: (1) transesophageal echocardiographic visualization of the atrio-esophageal interface, with probe retraction before the energy delivery; (2) lifting the ablated tissue away from the esophagus during an energy application; and (3) a 30 s cool-off and irrigation period after the energy delivery. The esophageal temperature was recorded using an insulated multisensory intraluminal esophageal temperature probe (Circa S-Cath™). Of the 20 patients enrolled, 7 patients had paroxysmal atrial fibrillation (AF), 8 persistent AF and 5 longstanding persistent AF. The average maximum luminal esophageal temperature observed was 36.2 ± 0.7 °C (34.8–38.2 °C). In our clinical experience, no abrupt increase in the luminal esophageal temperature above the baseline was observed. Since no measurements exceeded the threshold of 39 °C, no prompt interruption of energy delivery was required. Intraluminal esophageal temperature monitoring is feasible and can be helpful in confirming correct catheter position and safe energy application in bipolar epicardial left atrial ablation. Intra-procedural preventive mitigations should be implemented to reduce the risk of esophageal temperature rises.
Hysterectomy: Let’s Step Up the Ladder of Evidence to Look Over the Horizon
Authors: Giannini Andrea , D’Oria Ottavia , Bogani Giorgio , Di Donato Violante , Vizza Enrico , Chiantera Vito , Laganà Antonio , Muzii Ludovico , Salerno Maria , Caserta Donatella , Gerli Sandro , Favilli Alessandro
Published: November 2022

Hysterectomy is one of the most common non-obstetric gynecological surgical procedures carried out in Western countries [...]
Spontaneous Osteonecrosis of the Knee: State of the Art
Authors: Serrano Daniel Veloz , Saseendar Samundeeswari , Shanmugasundaram Saseendar , Bidwai Rohan , Gómez Diego , D’Ambrosi Riccardo
Published: November 2022

Osteonecrosis is a terrible condition that can cause advanced arthritis in a number of joints, including the knee. The three types of osteonecrosis that can affect the knee are secondary, post-arthroscopic, and spontaneous osteonecrosis of the knee (SPONK). Regardless of osteonecrosis classification, treatment for this condition seeks to prevent further development or postpone the onset of knee end-stage arthritis. Joint arthroplasty is the best course of action whenever there is significant joint surface collapse or there are signs of degenerative arthritis. The non-operative options for treatment at the moment include observation, nonsteroidal anti-inflammatory medications (NSAIDs), protective weight bearing, and analgesia if needed. Depending on the severity and type of the condition, operational procedures may include unilateral knee arthroplasty (UKA), total knee arthroplasty (TKA), or joint preservation surgery. Joint preservation techniques, such as arthroscopy, core decompression, osteochondral autograft, and bone grafting, are frequently used in precollapse and some postcollapse lesions, when the articular cartilage is typically unaffected and only the underlying subchondral bone is affected. In contrast, operations that try to save the joint following significant subchondral collapse are rarely successful and joint replacement is required to ease discomfort. This article’s goal is to summarise the most recent research on evaluations, clinical examinations, imaging and various therapeutic strategies for osteonecrosis of the knee, including lesion surveillance, medicines, joint preservation methods, and total joint arthroplasty.
Transcatheter Left Atrial Appendage Occlusion: A Multi-Center Real Life Experience
Authors: Arow Ziad , Hornik-Lurie Tzipi , Gabarin Mustafa , Omelchenko Alexander , Barashi Rami , Arnson Yoav , Assali Abid , Pereg David
Published: November 2022

(1) Background: left atrial appendage occlusion (LAAO) is considered an effective and relatively safe treatment for the prevention of thromboembolic events in patients with atrial fibrillation and a contra-indication for anticoagulation. We present a large multicenter real-world experience of transcatheter LAAO implementation in patients with atrial fibrillation who cannot be treated with chronic anti-coagulation; (2) Methods: included were atrial fibrillation patients who underwent transcatheter LAAO between 1 January 2016 and 30 June 2021. The study was conducted using the electronic health record database of Clalit Health Services (CHS). The primary outcomes included hemorrhagic and ischemic stroke following LAAO; (3) Results: included were 389 atrial fibrillation patients. During a median follow-up of 2.1 years, 13% patients had ischemic cerebrovascular accident (CVA), and 4.4% patients had hemorrhagic CVA. While the risk of ischemic stroke increased gradually over time, the risk of hemorrhagic CVA was highest during the first 3 months following the procedure. Moreover, previous ischemic stroke was the only significant predictor for both hemorrhagic and ischemic stroke following LAAO; (4) Conclusions: while the annual performance rate of transcatheter LAAO has increased significantly over the past years, post procedural long-term prognosis remains poor with a substantial risk of both thrombotic and bleeding events.
Efficacy and Side Effect Profile of Intrathecal Morphine versus Distal Femoral Triangle Nerve Block for Analgesia following Total Knee Arthroplasty: A Randomized Trial
Authors: Janiak Marek , Kowalczyk Rafal , Gorniewski Grzegorz , Olczyk-Miiller Kinga , Kowalski Marcin , Nowakowski Piotr , Trzebicki Janusz
Published: November 2022

(1) Background: The management of postoperative pain after knee replacement is an important clinical problem. The best results in the treatment of postoperative pain are obtained using multimodal therapy principles. Intrathecal morphine (ITM) and single-shot femoral nerve block (SSFNB) are practiced in the treatment of postoperative pain after knee replacement, with the most optimal methods still under debate. The aim of this study was to compare the analgesic efficacy with special consideration of selected side effects of both methods. (2) Materials and methods: Fifty-two consecutive patients undergoing knee arthroplasty surgery at the Department of Orthopedics and Traumatology of the Medical University of Warsaw were included in the study. Patients were randomly allocated to one of two groups. In the ITM group, 100 micrograms of intrathecal morphine were used, and in the SSFNB group, a femoral nerve block in the distal femoral triangle was used as postoperative analgesia. The other elements of anesthesia and surgery did not differ between the groups. (3) Results: The total dose of morphine administered in the postoperative period and the effectiveness of pain management did not differ significantly between the groups (cumulative median morphine dose in 24 h in the ITM group 31 mg vs. SSFNB group 29 mg). The incidence of nausea and pruritus in the postoperative period differed significantly in favor of patients treated with a femoral nerve block. (4) Conclusions: Although intrathecal administration of morphine is similarly effective in the treatment of pain after knee replacement surgery as a single femoral triangle nerve block, it is associated with a higher incidence of cumbersome side effects, primarily nausea and pruritus.
Preform Porosity and Final Thickness Variability Prediction after Controlled Post-Infusion External Pressure Application with the FEA Model
Authors: Zhilyaev Igor , Chang Shun-Hsyung , Shevtsov Sergey , Snezhina Natalia
Published: November 2022

One of the reasons for the insufficiently wide use of the low-cost and low-labor vacuum infusion process in the production of polymer composite structures is the uneven distribution of pore pressure, porosity, and preform thickness at the final stage of filling the preform with liquid resin. This article presents the results of a theoretical study of the factors that govern the effectiveness of the known method of external controlled pressure on the preform in order to eliminate or significantly reduce the listed disadvantages. The study includes an analysis of scenarios for the implementation of this method, which differ in the state of the resin gate when external pressure is applied to the preform (open or closed), as well as the pressure in the vacuum vent (maintained unchanged or gradually increased to atmospheric pressure). The research tool was a finite element (FE) model that simulates resin flow according to Darcy’s law and controlled boundary conditions for a thin-walled rectangular preform. The results of the study confirmed the effectiveness of the process in achieving a more uniform distribution of porosity and preform thickness and are good qualitative agreement with the results of borrowed experiments, revealing the conditions for the occurrence of critical situations associated with the possible penetration of air into the preforms through the vacuum port and the reverse flow into the preform of the resin previously forced out through the resin gate.
A Comprehensive Account of the Rust Genus Skierka (Skierkaceae)
Authors: Balkrishna Acharya , Gautam Ajay Kumar , Avasthi Shubhi , Niranjan Mekala , Verma Rajnish Kumar , Arya Vedpriya , Kumar Ashwani , Karunarathna Samantha C. , Suwannarach Nakarin
Published: November 2022

The rust genus Skierka belonging to the phylum Basidiomycota was described in 1900 by Raciborski with Skierka canarii as the type species. The published literature on this rust genus reveals its ambiguity in taxonomic placement. It was challenging to taxonomically delineate and precisely identify each species within this genus due to the species sharing some common characteristics. The latest studies based on morphology taxonomy and molecular characteristics, however, have solved this puzzle now and placed this genus in its new family Skierkaceae. To understand all about the genus Skierka, this compilation was carried out to unveil the general characteristics, history, diversity, distribution, ecology, morphology and molecular taxonomy of different species of Skierka. After exploring 14 species of Skierka, it was observed that this genus is distributed in seven plant families in 19 countries all over the world. The genus appears to be well-represented in Asian and South American counties. This rust has not been reported from any European countries to date. The morpho-taxonomy of all species is well studied, but molecular analyses are still required. Only two species of the genus namely S. robusta and S. diploglottidis were identified based molecular analyses. Therefore, further studies should be focused on epitypifying the taxa that are too old and updating their taxonomy based on molecular, biochemical, and physiological aspects along with morphological characteristics. Multiple analytical methods should be considered when dealing with multi-locus datasets. This will increase our understanding of the diversity, distribution, and identification of these rust fungi.
Genomic and Metabolomic Analyses of the Medicinal Fungus Inonotus hispidus for Its Metabolite’s Biosynthesis and Medicinal Application
Authors: Zhang Rui-qi , Feng Xi-long , Wang Zhen-xin , Xie Tian-chen , Duan Yingce , Liu Chengwei , Gao Jin-ming , Qi Jianzhao
Published: November 2022

Inonotus hispidus mushroom is a traditional medicinal fungus with anti-cancer, antioxidation, and immunomodulatory activities, and it is used in folk medicine as a treatment for indigestion, cancer, diabetes, and gastric illnesses. Although I. hispidus is recognized as a rare edible medicinal macrofungi, its genomic sequence and biosynthesis potential of secondary metabolites have not been investigated. In this study, using Illumina NovaSeq combined with the PacBio platform, we sequenced and de novo assembled the whole genome of NPCB_001, a wild I. hispidus isolate from the Aksu area of Xinjiang Province, China. Comparative genomic and phylogenomic analyses reveal interspecific differences and evolutionary traits in the genus Inonotus. Bioinformatics analysis identified candidate genes associated with mating type, polysaccharide synthesis, carbohydrate-active enzymes, and secondary metabolite biosynthesis. Additionally, molecular networks of metabolites exhibit differences in chemical composition and content between fruiting bodies and mycelium, as well as association clusters of related compounds. The deciphering of the genome of I. hispidus will deepen the understanding of the biosynthesis of bioactive components, open the path for future biosynthesis research, and promote the application of Inonotus in the fields of drug research and functional food manufacturing.