bluuebunny/crossref_metadata_2025 huggingface dataset:
Polypharmacology of Some Medicinal Plant Metabolites Against SARS-CoV-2 and Host Targets: Molecular Dynamics Evaluation of NSP9 RNA Binding Protein
Authors: Bandyopadhyay Suritra , Abiodun Omobolanle Abimbola , Ogboo Blessing Chinweotito , Kola-Mustapha Adeola Tawakalitu , Attah Emmanuel Ifeanyi , Edemhanria Lawrence , Kumari Ankita , Jaganathan Ravindran , Adelakun Niyi Samuel
Published: September 2020

Background: Medicinal plants, as rich sources of bioactive compounds with antiviral properties, are now being explored for the development of drugs against SARS-CoV-2.Aims: Identification of promising compounds for the treatment of COVID-19 from natural products via molecular modelling against NSP9, including some other viral and host targets and evaluation of polypharmacological indications.Main methods: A manually curated library of 521 phytochemicals (from 19 medicinal plants) was virtually screened using Mcule server and binding interactions were studied using DS Visualiser. Docking thresholds were set based on the scores of standard controls and rigorous ADMET properties were used to finally get the potential inhibitors. Free binding energies of the docked complexes were calculated employing MM-GBSA method. MM-GBSA informed our choice for MD simulation studies performed against NSP9 to study the stability of the drug-receptor interaction. NSP9 structure comparison was also performed. Key findings: Extensive screening of the molecules identified 5 leads for NSP9, 23 for Furin, 18 for ORF3a, and 19 for interleukin-6. Ochnaflavone and Licoflavone B, obtained from Lonicera japonica (Japanese Honeysuckle) and Glycyrrhiza glabra (Licorice), respectively, were identified to have the highest potential multi-target inhibition properties for NSP9, furin, ORF3a, and IL-6. Additionally, molecular dynamics simulation supports the robust stability of Ochnaflavone and Licoflavone B against NSP9 at the active sites via hydrophobic interactions, H-bonding, and H-bonding facilitated by water.Significance: These compounds with the highest drug-like ranking against multiple viral and host targets have the potential to be drug candidates for the treatment of SARS-CoV-2 infection that may possibly act on multiple pathways simultaneously to inhibit viral entry and replication as well as disease progression.
Tricyclic 2-Aminopyridinium Derivatives with Aggregation-Induced Emission for Concomitant Bacterial Discrimination and Inhibition
Authors: Wang Bingnan , Wu Haozhong , Hu Rong , Liu Xiaolin , liu zhiyang , Wang Zhiming , Qin Anjun , Tang Ben Zhong
Published: September 2020

The development of new ionic compounds with aggregation-induced emission (AIE) has been widely noticed. They can not only effectively solve the problem of aggregation-caused quenching (ACQ) encountered in conventional fluorescent dyes, but also exhibit promising applications in biological imaging, diagnosis and therapy, etc. However, such AIE system should be further developed. In this work, a series of novel cationic AIE luminogens (AIEgens) of tricyclic 2-aminopyridinium derivatives with seven-membered rings were designed and synthesized via a simple multi-component reaction, which exhibit the ability to specifically stain gram-positive bacteria. Meanwhile, they also possess excellent bacteriostatic ability for S. aureus in liquid medium and solid agar plates, of which the minimum inhibitory concentration (MIC) value is between 4 and 8 µg/mL. In addition, these molecules showed mitochondria-targeting capability in hydrophilic AIEgens and specific staining lysosomes in lipophilic AIEgens by wash-free process in living cells. These AIEgens with bacteriostatic activity hold great promise for distinguishing bacteria and inhibiting bacterial infection in clinical trial.
Understanding the Solid-State Assembly of Pharmaceutically-Relevant N,N-Dimethyl-O-Thiocarbamates in the Absence of Labile Hydrogen Bonds
Authors: Tan Davin , Ng Zi xuan , Ganguly Rakesh , Li yongxin , Soo Han Sen , Garcia Felipe
Published: September 2020

There are many pharmaceutical compounds that do not contain N-H, O-H, and S-H hydrogen-bond donor functional groups. Some of these compounds are N,N-disubstituted O-thiocarbamates which exhibit desirable medicinal properties, yet the study of these important molecules in the solid-state has been relatively unexplored. Herein, we report the synthesis and analysis of a series of N,N-dimethyl-O-thiocarbamates, and use X-ray diffraction techniques to gain insight into how these molecules self-assemble in the solid-state and discern certain packing patterns. It was observed that the aryl-thiocarbamate C-O bonds are twisted such that the planar aryl and carbamate moieties are orthogonal. Such a non-planar molecular geometry affects the way the molecules pack and crystal structure analyses revealed four general modes in which the molecules can associate in the solid-state, with some members of the series displaying isostructural relationships. The crystal structure of a well-known yet unreported O-thiocarbamate drug, Tolnaftate, is also reported. Additionally, Hirshfeld surface analysis was also performed on these compounds as well as several related O-thiocarbamates in the literature.
Copper (II) Phthalocyanine Effects On Solid Propellant Combustion
Authors: Marinho George Santos , de Farias Robson
Published: September 2020

In the present work, the effects of copper (II) phthalocyanine, CuP (C32H16CuN8) on the combustion of rocket solid propellant is investigated. For this purpose, parameters such as ignition temperature, mass and volume of generated gases are measured. For such purpose, the sucrose-potassium nitrate (KNSu) was employed as a “model system”. It was found that CuP interferes with the combustion of the KNSu propellant, inhibiting the thermal degradation of potassium carbonate and also decreasing the ignition temperature of KNSu. It was identified that, in a percentage of 50%, CuP reduces the ignition temperature of KNSu by ~ 60 ºC.
Calculation of Spin–orbit Couplings Using RASCI Spinless One-Particle Density Matrices: Theory and Applications
Authors: Carreras Abel , Jiang Hanjie , Pokhilko Pavel , Krylov Anna I. , Zimmerman Paul M. , Casanova David
Published: September 2020

This work presents the formalism and implementation for calculations of spin–orbit couplings (SOCs) within the Breit–Pauli (BP) Hamiltonian using zero-order (non- relativistic) wave-functions described by the restricted active space configuration in- teraction (RASCI) method with general excitation operators: excitation energies, spin- flip, ionization potential, and electron attachment. The implementation is based on the application of Wigner–Eckart’s theorem within the spin space, which allows the computation of the entire SOC matrix based on the explicit calculation of just one tran- sition between the two spin-multiplets. Numeric results for a diverse set of atoms and molecules highlight the importance of balanced treatment of correlation and adequate basis sets, and illustrate overall robust performance of RASCI SOCs. The new imple- mentation is a useful addition to a methodological toolkit for studying spin-forbidden processes.
International Conference on Emerging Trends in Biomedical and Health Applications (ICETBHA-2020)
Authors: Lakshmi T  , Deepa Gurunadhan  , Mahesh R  , Raghunandha Kumar S
Published: September 2020

The International Conference on Emerging Trends in Biomedical and Health Applications (ICETBHA -2020) is an initiative undertaken by the Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India. The Conference aims to provide a platform for scientific and knowledge exchange and also explore the recent trends in biomedical field. The purpose of this conference is to explore the Novel concepts by the scientific experts involved in the biomedical research and health care sector. This conference focus on the presentations, Interaction between the expertise and students, research scholars on the updated information on Nano medicine, Cancer therapeutics, Pharmacogenomics, Awareness survey on health care, Microbial applications, Molecular biological investigations, Genetic studies, Drug therapy, Pharmacognostic evaluation, Dental applications in the field of Biomedicine and its use in Oral health care. This conference featured the keynote speaker and invited lectures from Countries like South Korea, USA, Japan. Scientific presentation included Paper /e-poster with diverse topics on the cutting edge research and novel innovations.
Rosehip Neuron - A Review
Authors: Keerthana B  , Yuvaraj Babu K  , Gayathri R
Published: September 2020

Rosehip neuron is a special type of neuron present only in humans. It has inhibitory actions over other cells. It is present in the first layer of the human cerebral cortex. These neurons have an inhibitory action over other neuronal cells. This research is seen as a scoping literature review. In seeking to identify the relevant literature from the past twenty years, we used common databases such as Pubmed, Google scholar online websites. Nearly 30 reference articles are collected related to the topic. The obtained articles were later read thoroughly and understood. Rosehip neurons are unique neurons and can treat neuronal disorders. It can also maintain the activities of other neuronal cells. It is concluded that more research has to be done on the actions of rosehip neurons and about its functions. This review is an attempt to understand the various functions of Rosehip neurons in humans. Further research is needed to know about its full use of humanity.
Association of Rheumatoid Arthritis with Dental Health - A Mini Review
Authors: Sheetal Kumari  , Vijayashree Priyadharsini J  , Dinesh Premavathy
Published: September 2020

Autoimmune disorders represent a cluster of diseases related to dysregulation of the immune system or misrecognition of self from non-self. Rheumatoid arthritis (RA) is a chronic inflammatory condition involving the joints. It is one of the most common forms of inflammatory arthritis reported globally. The incidence rate of RA is found to be the highest among middle-aged women. There happens to be a close relationship between RA and dental health. The inflammatory processes triggered by microbes and other endogenous factors affects the bone health resulting in the resorption of bones. This condition is observed in aggressive and chronic periodontitis. The main objective of the present literature review was to evaluate the association of rheumatoid arthritis with dental health such as gingivitis, tooth loss and periodontitis. Furthermore, the present literature review throws light on the common markers which might be associated with both the disease conditions. The current review identified novel markers that were associated with rheumatoid arthritis which were implicated in dental health also. Hence management of rheumatoid arthritis might as well reduce the damage caused by bone resorption and could aid in the prevention of premature tooth loss.
Knowledge and Attitude of UG Dental Students about Nanotechnology in Dentistry
Authors: Mabbithasri A  , Yuvaraj Babu K  , Gayatri Devi R
Published: September 2020

The term nano is derived from a Greek word ‘nannos’ which means dwarf. Nanotechnology is the science that deals with physical, chemical and biological properties of structures at the nanoscale. Nanotechnology is used in science, biotechnology, computer technology, electronics, agriculture, household as well as dentistry. Nanotechnology was used in dentistry in the early 1970s in microfilled composites comprising particles less than 100nm diameter. In recent times the composite particles are used that range from 20-600nm. In dentistry it is mainly used in restoration, orthodontic treatment and injecting local anesthesia and has many other uses. The main aim of nanotechnology in dentistry is to prevent any oral disease rather than treating it. The aim of the study is to evaluate the knowledge and attitude of UG dental students about nanotechnology in dentistry. A cross-sectional prospective survey was created in google docs with a questionnaire containing 15 questions, and the link was shared to 100 UG dental students. The results were analysed and represented as a pie chart and bar diagrams. Majority of (60%) of them were aware about nanotechnology, and few were not aware (40%). 46% of students were aware of the use of nanotechnology in dentistry, and 52% of participants felt it nanomaterials was not affordable. From the results obtained, the knowledge and attitude among Undergraduate dental students about nanotechnology in dentistry was found to be average.
Knowledge, prevalence and risk factors of rheumatoid arthritis among middle-aged and old aged population
Authors: Sachin Aditya B  , Karthik Ganesh Mohanraj  , Vishnu Priya V
Published: September 2020

Rheumatoid Arthritis is a chronic disorder and affects the lining of joints and functioning of various other vital organs like the heart, kidneys and lungs. It is an autoimmune disorder where the body's immune system attacks its tissues. Most patients experience a chronic fluctuating course of a disease that, despite therapy, may result in progressive joint destruction, deformity, disability, and even premature death. Joints most commonly affected are those with the highest ratio of synovium to articular cartilage. It is more common in women than in men. Its symptoms include tender and warm joints which may lead to joint deformities in extreme cases. This study involved 100 participants of age ranging from 16-55 years. A well-structured questionnaire based on personal, socioeconomic information along with symptoms and treatment of RA was prepared and circulated online through Google forms among the participants. The results showed that most of the participants were aware of the common symptoms of RA and their risk factors and more than 60% of participants were students, over 90% of respondents said it is genetic. Smoking can increase the chance of attaining it. Disability from RA causes major economic loss and can have a profound impact on families. However, it can be managed treated and even remitted in some cases if proper habits like exercise are followed. It should be diagnosed as early as possible for better chances of remission.
The Golden Age of China-Taiwan Relations: The Explanation and Its Future
Authors: Wiratama Daniel Tantra
Published: September 2020

The past eight years since 2008 under the leadership of Ma Ying-jeou, the relations between China and Taiwan have been experiencing the golden age. By cooperating in many sectors, like economic partnership; social interactions; tourism and some political dialogues, both countries have been building a good relationship between them. Looking back to the past, China and Taiwan have a long series of conflicts, which ended in the Chinese Civil War 1949 with the victory of the Chinese Communist party which has now become the People’s Republic of China. Meanwhile, its opposing democratic party has now become the Republic of China (Taiwan). Since then, China and Taiwan’s relations have been on a standstill Ma Yingjeou rose to power as the president of Taiwan. By using the concept of Economic Interdependence and Conflict in World Politics by Mark J.C. Crescenzi, this paper aims to explain how the golden age of China-Taiwan relations have been going on in the past eight years up until now, as well as the future of the relations itself under the new president of Taiwan, Tsai Ing-we. This paper has the following research question: how has the good relation between China and Taiwan been built since 2008, considering their previously severed relations in the past?
Lion’s Roar in SEA: Singaporean Way in Increasing the Awareness of Cybersecurity
Authors: Rizki Aufar
Published: September 2020

Nowadays, where almost all aspect are digitilized have caused a massive increase of cyber threats which is a tangible threats for human beings. However, cybersecurity still has a second priority to accomplish for mostly countries, just few country who put big concern to this issue. As the Chair of ASEAN 2018, Singapore has made a project in strengthening the collective resillience of cybersecurity. The goal of this project is to increase the awareness of ASEAN countries in tackling cyberthreats in which it endangers the cybersecurity
The Eighth Sustainable Development Goal considering the economic system and its contradictions – A Critique
Authors: Pinho José António De Sousa
Published: September 2020

This article focuses on the eighth Sustainable Development Goal (SDG) for the global community, analysing its objectives and recommendations that are to be achieved by 2030 in the sectors of economic growth and employment. It is a critique of the SDG chosen, in light of the current economic system and its contradictions, taking into account the new factors of the decade, such as technology and the environmental crisis. Economic growth was present in every economic analysis in the past decade, but should it be the focus of the next? The current environmental concerns have forced the global community to rethink the way we look at economic growth and the system in general. The article will also explore the contradictions in employment and work while attempting to explain the problems of this sector. A special attention will be given to profit and the way it prevents the creation of decent jobs. The new possibilities of the green economy and the technological progress will be taken into account and developed. It will finish with a reflection on the economic system in general and the SDGs, while also proposing a solution to the problems of the next decades concerning the economic and employment sector.
Konsistensi Indonesia sebagai Kekuatan Menengah: Studi Kasus Respon Deterrence di Natuna
Authors: Debora Amy
Published: September 2020

As Jakarta is working to resolve the South China Sea (SCS) territorial dispute through its role as an honest broker, Beijing seems to lead the SCS conflict right into the foremost defense of the Republic of Indonesia. This is indicated by the China Coast Guard (CCG) aggressive actions in guarding illegal fishing in Natuna Sea. The conflict escalation raises the question of whether Natuna will enter into the SCS territorial dispute. However, these concerns did not occur due to the appropriate response of Jakarta in maintaining the stability of the region without undermining its defense of its territorial sovereignty. Significantly strengthening the defense in Natuna does not create a security dilemma for ASEAN member countries as it is done in conjunction with the border diplomacy effort. This shows the success of border diplomacy as indirect deterrence against China. This paper will be divided into 4 sections, first the author will give an overview of the SCS conflict and the threats to maritime security in Natuna. Next will be described the concept of ‘middlepowermanship’ according to Cooper, Higgot and Nossal who states that the middle power is reflected from the characteristics of foreign policy. This paper finds that the response reflects the Indonesia’s consistency as a middle power. Proved by Indonesia’s niche diplomacy under Jokowi administration, as well as the role of Jakarta as coalition builder for ASEAN.
Challenges Faced by English Teacher in Teaching: Case Study of Junior High School in Banjarnegara Regency
Authors: Utomo Hari Widi , Kusakabe Tatsuya , Sultoni Achmad , Setyowati Dhina
Published: September 2020

Teaching English is not a very easy job and becomes a challenging task for the Junior High School teacher in Banjarnegara regency that is located in a mountainous area and the majority of the people love to speak their mother tongue in their daily life. The main purpose of this study was to investigate the challenges faced by an English teacher in the teaching as well as what the solution/recommendation they made. This study employed the qualitative methods in which questionnaires and interview guide utilized and hundred and twenty-five (N=125) teachers were purposely and conveniently sampled from Junior High School English teachers in Banjarnegara regency. The results revealed that the challenges faced in teaching English are divided into four parts. The first challenges were from the teachers. These challenges are less of teaching material, teaching design, classroom management, ICT skill, many teaching administration, job loaded, and memory decrease. The second was from the students. Those are lack of vocabulary, loss of motivation, and juvenile delinquencies. The third was from schools. Schools had limited facilities, which can be utilized by teachers and students in teaching activities such as; limited dictionary, projector, and language laboratory. The fourth was from the parents. Many parents from the village have low education and future vision so it influenced their children's education. The study also gives three recommendations for succeeding in teaching English such as; (1) teachers should make teaching contract at the beginning of the semester, (2) principals send teachers joining to MGMP meeting and Continuous Professional Development activity, (3) schools give motivation to students and parents periodically.
PURUN: MERAJUT EKOLOGI DAN TRADISI DI KOTA TIKAR DALAM KONTEKS IPS
Authors: Suprapto Wasis
Published: September 2020

Purun (eleocharis dulcis) adalah sejenis tumbuhan semak yang tumbuh di daerah rawa. Tumbuhan jenis inioleh masyarakat Menang, Pedamaran, Ogan Komering Ilir (OKI) dikreasi menjadi aneka kerajinan bernilai ekonomis tinggi. Kreasi itu terdiri dari tikar, tas, dan aneka anyaman lainnya sehingga membuat daerah ini mendapat julukan sebagai Kota Tikar. Uniknya proses pembuatan aneka kerajinan tersebut dilakukan tanpa merusak alam. Alambenar-benar dijaga dan dirawat kelestariannya karena mampu memberi dampak sosial, ekonomi, dan budaya pada masyarakat setempat. Tradisi yang mampu menumbuhkan semangat gotong royong, kerjasama, dan kreativitastetap terjaga di tengah citra duta atau bandit sosial yang melekat pada orang OKI. Oleh sebab itu, diperlukan usaha merajut tradisi, melestarikan ekologi, dan merubah citra duta yang salah satunya dapat dilakukan dengan mengoptimalkan peran pendidikan melalui mata pelajaran IPS. IPS dipilih karena kajiannya membahas tentang persoalan sosial masyarakat. Realisasi tersebut dilakukan dengan (1) perencanaan pembelajaran dengan cara mengintegrasikan tradisi purun dan citra duta dengan KI KD IPS, (2) Penerapan pembelajaran melalui pendekatan scientifik disertai model pembelajaran diskusi dan karyawisata untuk mengelaborasi fenomena IPS (3) Penilaian hasil belajar IPS berdasarkan projek.Tiga langkah itu dilakukan untuk membuat pembelajaran IPS lebih menarik, bermakna, serta mampu menumbuhkan kepekaan sosial siswa.
PENINGKATAN HASIL BELAJAR MELALUI IMPLEMENTASI MODEL PEMBELAJARAN DISCOVERY LEARNING DENGAN TEHNIK CONCEPT MAPPING BAGI SISWA SMA NEGERI 1
Authors: Mustikorini Mustikorini
Published: September 2020

Permasalah dalam penelitian ini adalah bagaimanakah peningkatan hasil belajar siswa terhadap materi Ancaman Terhadap Integrasi Nasional dan berapa besar peningkatan hasil belajar siswa pada aspek  pengetahuan yang berbentuk tes tertulis dan aspek ketrampilan.Teknik pengumpulan data menggunakan lembar observasi,  dan tes tertulis. Validitas data dilakukan oleh Expert Judgment dalam penelitian ini adalah teman sejawat yang lebih senior. Hasil penelitian menunjukkan bahwa (1) nilai rata-rata ulangan harian siswa yang tuntas pada prasiklus adalah 77,07(36%),  (2) nilai rata-rata pada siklus I adalah 77,23 (47 %), dan (3) nilai rata-rata pada siklus 2 adalah 84,07 (78%) pada siklus II. Hasil penelitian tersebut dapat disimpulkan bahwa implementasi pembelajaran Discovery Learning dengan tehnik Concept Mapping  dapat meningkatkan hasil belajar materi Ancaman Terhadap Integrasi Nasional di kelas X MIPA 2 SMA Negeri 1 Wirosari Semester Genap Tahun Pelajaran 2018/2019 secara signifikan.
Sustainable Human Resource Management and Organisational Performance: An Integrating Theoretical Framework for Future Research
Authors: Muñoz-Pascual Lucía , Galende Jesús
Published: September 2020

This paper identifies and analyses six relevant approaches for the analysis of Sustainable Human Resource Management and Organizational Performance: Resource-Based View, Dynamic Capabilities View, Knowledge-Based View, Behavioral Theory, Human Relations Theory, and Cooperative Systems and Ambidextrous Organizations. They are complementarity approaches. They can all be applied to the analysis of a specific resource or capability for sustainable human resource management (HRM) and, consequently, organisational performance. However, the contributions made by the Resource-Based View and the new approach of Ambidextrous Organizations seem to be the most comprehensive approaches for studying sustainable HRM from an internal perspective of firms that allows the long-term development of their organizational and society performance.
Змістовa організація та лексико-стилістичні особливості польської дипломатичної документації на адресу України, датованої груднем 1991 року
Authors: Васейко Юлія , Цьолик Наталія
Published: September 2020

The article deals with the semantic structure and the most productive groups of the lexical stylistic devices that function in the Polish foreign diplomatic documentation addressed to the Ukrainian side in December, 1991, namely Statements of the Council of Ministers of the Republic of Poland (1991/12/02), Note from the Ministry of Foreign Affairs of the Republic of Poland (1991/12/27), Telegram of the President of the Republic of Poland Lech Wałęsa  (1991/12/3). The methods of typological (a study of the structure of diplomatic documents), descriptive (an analysis of the semantic content), functional (a research of the purpose of a note, a statement, a telegram), comparative (comparison of the language, graphical, and informative content of documentation) and linguistic analysis have been used to reveal the content organization of documents. All of them have common features, namely the text elements that contain logical information chains of the Ukrainian Independence recognition. However, they differ in some content aspects: the statement additionally informs about the issue of disarmament and military reduction; the telegram implies domination of the emotionally-expressive content which is verbally emphasized by the superlative form of the adjective; the note represents the first steps of the diplomatic relationship development such as the exchange of ambassadors. The study has revealed that the structure of all the official documents under the study is traditional for this functional style. Moreover, it includes the relevant appeals (the note, the telegram), complimentary forms of conclusion (the note), signature (the note, the statement, the telegram), information about the date and location the document creation (the note, the telegram). On the lexical level, all documents contain the elements of literary vocabulary that are emphasized by nouns, less frequently by adjectives, participles, verbs, adverbial participles, diplomatic terminology and cliches. They are used to provide the text accuracy, clarity, logic, conciseness, standardization, courtesy and highlight the value of the information, its credibility, and the relevance of the international law norms
Review of the International scientific-practical conference "International Law in Supporting the Processes of Regional Integration", Kazan
Authors: Davletgildeev Rustem , Adullin Adel' , Garaev Marsel' , Sinnyavskiy Aleksey
Published: September 2020

The review is dedicated to the international scientific and practical conference «International law in regional integration processes implementation» held at the Faculty of Law of Kazan Federal University in autumn 2019. The conference was attended by leading international law scholars from the Moscow State University n.a. M.V. Lomonosov, Moscow State Law University n.a. O.E. Kutafin, MGIMO University, RUDN University, The Institute of Legislation and Comparative Law under the Government of the Russian Federation, High School of Economics, Nijny Novgorod State University n.a. N.I. Lobachevsky, The Ural State Law University, Yaroslavl State University, academics from universities of EAEU Member States, as well as judges of the Court of Eurasian Economic Union. During the conference, the participants considered the main problems of the theory and methodology of international law, the role of international organizations in ensuring the international law, the role of international judicial institutions, as well as theoretical problems of legal integration in international and domestic law. The authors of this publication acquaint the readers with the programme, the main contents of the participant’s presentations and the results of the conference.
THE ROLE OF COMMITMENT AND RELATIONSHIP SATISFACTION ON FRANCHISEE LOYALTY / The Role Of Commitment And Relationship Satisfaction On Franchisee Loyalty
Authors: RUSMAN Rusni , SANUSI Abdullah , KARIM Ikawati
Published: September 2020

This study aims to examine the influence of commitment and relationship satisfaction on franchisee loyalty through the level of importance of each variable dimension. It gives new perspective of how to reach franchisee loyalty through each dimension of commitment and relationship satisfaction. Dimensions of variable are focused on franchising and from franchisee perspective namely: franchisor attitude, raw material, payment method, franchisor support. Data is collected from questionnaire of 52 respondents and analyzed with multiple linear regression. The results of regression coefficient indicate that commitment has a significant effect by 0,014 which is lower than relationship satisfaction 0,473. The F test shows that commitment and relationship satisfaction jointly influence franchise loyalty while regression coefficient of R Square is 0,883. It indicates that the variable commitment and variable relationship satisfaction together affect the variable franchisee loyalty of 88.3%. This result explains that commitment and relationship satisfaction are two important variables in maintaining franchisee loyalty.
Fenomena Pekerja Anak (Kasus Pedagang Asongan Anak di Kawasan Ekonomi Khusus Mandalika, Lombok Tengah)
Authors: Anggraini Minawati , Nurjannah Siti , Inderasari Oryza Pneumatica
Published: September 2020

The phenomenon of child labor food street sellers is a complex problem which currently exists in both. This research is aimed to investigate phenomenon of a child food street in the Mandalika Economic Region and meaning of children’s rights for child food street sellers. The research method used is a phenomenology qualitative approach. The main resource of this research is children working as street food sellers. The research results show that being a food street seller is affected by past actions in order to achieve goals. They work almost every day after school time. As street food sellers, most of them define their rights as a child as being  fulfilled but some are not. The conclusion that can be drawn from this research is (1) children who become food street sellers have two sets of motives. The first relate to their friends, family economic conditions, up bringing patterns, looseness of school rules, and self-willingness. The secondary motives relate to playing to strengthen social relations, to assist their family’s economic circumstances, to bring happiness to their family, to become free from homework, to be independent, and to improve their English. (2) The meaning of children’s rights for child food street sellers is the right to play, to receive education, protection, a name, nationality, food, health, recreation, equality,  and a role in development. The researcher gives some suggestions such as this study can be a reference for policy-making in the mentoring program.
Evaluation of knowledge and attitudes towards kidney transplantation in patients undergoing hemodialysis at Muhimbili National Hospital, Tanzania.
Authors: Richard Paul Mzee  , Obadia Venance Nyongole  , Nashivai Elias Kivuyo  , Mungeni Athanas Misidai  , Gudila Valentine Shirima  , Jackline Shoo  , Jackson Joseph Mlay
Published: September 2020

Renal replacement therapy (RRT) is the treatment of choice for patients with End Stage Renal disease (ESRD), RRT include dialysis and kidney transplantation. Some sub-Saharan African countries including Tanzania have improved nephrology services dialysis and kidney transplant. This study aimed to assess knowledge, attitude and practices towards kidney transplantation among patients undergoing dialysis at Muhimbili National Hospital. This was a hospital based cross-sectional study that was conducted at Muhimbili National Hospital. A total of 190 patients were interviewed, majority were males 133(70%) with the age range of 18-80 years. Most patients 183(96.35%) were aware of Kidney transplantation the main source of information 175(95.6%) being hospital with 159 (86.9%) patients being aware of rules guiding kidney transplantation and 166 (90.7%) were aware of lifelong medication use after kidney transplantation. Knowledge on transplant was noted in 115(62.8%) with all of them being willing to receive kidney from blood related relatives. Majority 188 (64.5%) patients were not sure whether live kidney donation was better than deceased kidney donation. Better knowledge may ultimately translate into the act of donation. Effective measures should be taken to educate people with relevant information with the involvement of media, doctors and religious scholars. Large proportion considers Kidney Transplant positively but it limited by shortage of donors.
Kecukupan Modal, Pembiayaan Bermasalah, dan Efisiensi Operasional Sebagai Determinan dari Profitabilitas Bank Muamalat Indonesia Periode 2012-2017
Authors: Elmadwita Yoni , Mubyarto Novi
Published: September 2020

This research aims to analyze the effect of capital adequacy, financing risk, and operational efficiency on the profitability of Bank Muamalat Indonesia. This research uses a quantitative descriptive approach, the object of research is the Capital Adequacy Ratio (CAR / KPMM) as a proxy for capital adequacy, Non-Performing Financing (NPF) as a proxy for financing risk, Operational Costs Operating Income (BOPO / REO) as a proxy for operational efficiency, and Return on Assets (ROA) as a proxy for profitability. The research subjects are the annual and quarterly financial reports of PT. Bank Muamalat Indonesia for the period 2012 - 2017. Methods of data analysis using multiple linear regression. The results showed that CAR had no significant effect on ROA. Meanwhile, NPF and BOPO have a negative and significant effect on ROA.

Penelitian ini bertujuan untuk menganalisis pengaruh kecukupan modal, pembiayaan bermasalah, dan efisiensi operasional terhadap profitabilitas Bank Muamalat Indonesia. Penelitian menggunakan pendekatan deskriptif kuantitatif, Objek penelitian adalah Capital Adequacy Ratio (CAR/KPMM) sebagai proksi dari kecukupan modal, Non-Performing Financing (NPF) sebagai proksi dari pembiayaan bermasalah, Biaya Operasional Pendapatan Operasional (BOPO/REO) sebagai proksi dari efisiensi operasional dan Return on Asset (ROA) sebagai proksi dari profitabilitas. Subjek penelitian adalah laporan keuangan tahunan (Annual Report) dan triwulanan PT. Bank Muamalat Indonesia periode 2012 – 2017. Metode analisis data menggunakan regresi linier berganda. Hasil penelitian diketahui bahwa CAR tidak berpengaruh signifikan terhadap ROA. Sementara itu, NPF dan BOPO mempunyai pengaruh negatif dan signifikan terhadap ROA.
Ekonomi Berdaulat dan Berkeadilan dalam Perspektif Muhammad Iqbal
Authors: Firdaus Abdullah
Published: September 2020

Religion is the basic capital in building a solid economy. Social welfare in an Islamic perspective is not only oriented towards fulfilling material needs but must be based on the principle of justice which considers the aspects of material, social and spiritual satisfaction for the individual as well as for the wider community. This paper is intended to explore the thoughts and economic vision initiated by Muhammad Iqbal. This study is a qualitative study using a content-analysis approach through data taken from various writings related to this research. In the end, this research concludes that economic justice will be realized if there is political sovereignty, and political sovereignty will be realized if there is independence. The concept of a just economy is born from religious guidance and teachings because it directly defines the concept of holistic welfare in the vital aspects of human needs.

Agama menjadi modal dasar dalam membangun perekonomian yang solid. Kesejahteraan sosial dalam perspektif Islam, tidak hanya berorientasi pada pemenuhan kebutuhan material saja akan tetapi ia harus berlandaskan kepada prinsip keadilan yang mempertimbangkan aspek kepuasan material, sosial dan spiritual bagi individu juga terhadap masyarakat luas. Tulisan ini dimaksudkan untuk mengeksplorasi pemikiran dan visi ekonomi yang digagas oleh Muhammad Iqbal. Kajian ini bersifat kualitatif dengan menggunakan pendekatan content-analysis melaui data-data yang diambil dari berbagai penulisan yang terkait dengan penelitian ini. Pada akhirnya penelitian ini menyimpulkan bahwa keadilan ekonomi akan terwujud jika ada kedaulatan politik, dan kedaulatan politik akan wujud jika ada kemerdekaan. Konsep ekonomi berkeadilan lahir sesungguhnya dari bimbingan dan ajaran agama karena ia secara langsung mendefinisikan konsep kesejahteran holistik aspek vital kebutuhan manusia.
Teaching English allomorphs through �Harry Potter and the Chamber of Secret� movie
Authors: Aniuranti Asfi , Suwartono Tono
Published: September 2020

The study is primarily concerned with the use of �Harry Potter and the Chamber of Secret� to teach English allomorphs in EFL classrooms. This paper is an alternative way to teach them as a significant element of pronunciation. The types examined are�Regular Past Tense, Regular Plural Number, Third Person Present, The Regular Possessive, and�Reduced IS and HAS. Besides the main highlight of allomorph pronunciation, the movie also contemplates some suprasegmental features called word stress and sentence intonation. The teachers may also utilize the movie through four phases. They are warm-up activity, completion, categorization, and production. Bringing a movie that has many benefits into EFL classrooms may lead to a good comprehension of English allomorphs to the students.
Salud mental, confinamiento y preocupación por el coronavirus: un estudio cualitativo
Authors: Vásquez Gabriela , Urtecho-Osorto Óscar Rolando , Agüero-Flores Maitée , Díaz Martínez Miguel José , Paguada Rosa María , Varela Melody Anette , Landa-Blanco Miguel , Echenique Yaraní
Published: September 2020

Este estudio cualitativo explora significados y experiencias de la preocupación por la COVID-19, el confinamiento y su relación con la salud mental. Incluyó 20 entrevistas semiestructuradas realizadas a 10 hombres y 10 mujeres. Se halló que hay personas preocupadas por la salud propia y la de sus seres significativos. Esto puede detonar reacciones psicosomáticas y ansiedad. Otras personas devalúan la gravedad del COVID-19 porque no se consideran vulnerables. Exponerse recurrentemente a información mediática resulta estresante, así que algunos evitan hacerlo. Otra preocupación es económica: reducción del acceso al mercado laboral y suspensión o disminución del ingreso. Algunos participantes experimentan alteraciones en los hábitos alimenticios y de sueño. Finalmente, aunque el confinamiento limita la recreación, los informantes han realizado actividades de ocio individuales y familiares.
Gender Axiologemes in the Novel “Aniko of the Nogo Clan” by Anna Nerkagi
Authors: Khazankovich Yuliya Gennad'evna
Published: September 2020

The article focuses on identifying and decoding culture-specific gender axiologemes in the Nenets novel. Scientific originality of the paper is conditioned by the fact that the researcher suggests a methodological approach to studying the northern prose and also by the fact that gender axiologemes in northern writers’ prose have not been previously investigated. The research objectives are as follows: to analyse the genesis of gender axiologemes, to reveal their functional and meaningful specificity in the Nenets novel. The following conclusions are justified: the Nenets “gender worldview” is manifested in everyday and ritual culture; in Nerkagi’s novel, it determines artistic content of axiologemes of family and loneliness, life and love, a man and a woman, which makes it unlike the traditional “female prose”.
Sten Nadolny’s Artistic Discovery: Phenomenon of Slowness
Authors: Vafina Alsu Hadievna , Reuter Kirsten Helmut
Published: September 2020

The paper aims to identify an artistic invariant of John Franklin’s system for success by the example of the novel “Die Entdeckung der Langsamkeit” (“The Discovery of Slowness”) by the German writer Sten Nadolny. Special attention is paid to analysing forms and techniques of artistic interpretation of the thematic content of the slowness phenomenon described by the example of the artistic biography of the famous seafarer John Franklin. Scientific originality of the study lies in the fact that the researchers reveal importance of the literary form for understanding the analysed phenomenon. The findings indicate that discreteness of reality is surpassed due to persistence of the main character’s perception.
Meta-Text in Fiction Text: Pragmatics and Functions
Authors: Kuznetsova Anna Vladimirovna
Published: September 2020

The paper aims to identify and describe pragmatic specificity of meta-text and its pragmatic functions in fiction text. The writer possesses a wide range of linguistic means allowing the reader to perceive the author’s and the personages’ consciousness through interpreting linguo-stylistic, compositional and other peculiarities of fiction text manifested in meta-text. Scientific originality of the study involves justifying a pragmatic potential of meta-text that performs a full range of pragmatic functions. The conducted research allows concluding that such a multi-functional meta-text contains different types of meta-textual markers, which broaden its linguo-cognitive and pragmatic potential.
Specificity of Translating Slang and Obscene Vocabulary (by the Example of Ozzy Osbourne’s Autobiography “I Am Ozzy”)
Authors: Vasenko Mariya Aleksandrovna
Published: September 2020

The research objective includes identifying translation techniques to transfer slang and obscene vocabulary in autobiographical works. The article examines specificity of the autobiographical text translation by the example of autobiography of the British rock singer and musician Ozzy Osbourne “I Am Ozzy” (2010) and its Russian translation conducted by Anna Borisovna Popova (2018). The researcher’s attention is focused on the use of slang and obscene vocabulary as a means to transfer the author’s intention. Scientific originality of the paper involves identifying specificity of translating pop culture figures’ autobiographies. The findings are as follows: the researcher describes translation techniques used by the translator to transfer the author’s individual style.
Issue of Moral Choice in V. V. Orlov’s Novel “The Apothecary”
Authors: Safron Elena Alexandrovna
Published: September 2020

The article considers specificity of a moral choice faced by the characters from V. V. Orlov’s fantasy novel “The Apothecary”, when they accidently free a Bereginya who grants wishes. The study aims to determine the ethical stance that the characters take in the situation of absolute permissiveness. The research is novel in that the moral issues upon which this work of fiction touches have previously received attention solely from the authors writing critical articles. As a result, it is found that the characters are not ready to do right with the Bereginya’s gift due to their lack of high spiritual aspirations, so consequences of this situation become tragic. But the novel’s protagonist evolves as a person: making his moral choice, the character renounces his stance of a passive observer and sacrifices his love to save Ostankino residents.
“Official Duties” vs “Creative Work” in G. R. Derzhavin’s Autobiographical Texts
Authors: Farafonova Oksana Antolievna
Published: September 2020

The article is written within fundamental problematics of literary criticism - the researcher considers correlation of the writer’s biography and creative work. The objective includes analysing G. R. Derzhavin’s autobiographical texts with a view to identify the place and role of the opposition “official duties - creative work” in self-identification of one of the leading poets of the XVIII century. Scientific originality of the study lies in the fact that G. R. Derzhavin’s “Memoirs” and “Explanations to Derzhavin’s Works” are for the first time analysed through the lenses of poetical and biographical self-reflexion and its role in the poet’s self-identification. The following conclusions are justified: the works under study have much in common, which indicates inseparability and homogeneity of civilian and creative elements in the poet’s creative and civil consciousness.
ANCAMAN BUDAYA POP (POP CULTURE) TERHADAP PENGUATAN IDENTITAS NASIONAL MASYARAKAT URBAN
Authors: Istiqomah Annisa , Widiyanto Delfiyan
Published: September 2020

Identitas nasional berkaitan dengan nilai-nilai, sejarah, dan cita-cita yang menyatukan suatu kelompok masyarakat dalam suatu ikatan. Identitas nasional dipahami sebagai suatu kondisi dinamis yang terbentuk dari faktor etnisitas, teritorial, bahasa, agama, dan sejenisnya, selain itu dari faktor pembangunan. Salah satu faktor yang mempengaruhi dinamika identitas nasional adalah globalisasi. Globalisasi dimaknai sebagai kebebasan masyarakat dunia dalam mengembangkan berbagai aspek kehidupan seperti ilmu pengetahuan, teknologi, nilai-nilai, dan budaya. Interaksi masyarakat dunia yang semakin mudah menyebabkan proses transmisi nilai-nilai budaya lintas negara seperti berkembangnya budaya pop di Indonesia. Penelitian menggunakan metode studi literatur dengan mengumpulkan berbagai referensi baik sumber primer dan sekunder yang relevan dengan ancaman budaya pop terhadap penguatan identitas nasional masyarakat urban. Hasil dari kajian penelitian menunjukkan bahwa budaya pop identik dengan perilaku kebarat-baratan yang cenderung pragmatis, hedonis, dan konsumtif. Ideologi tersebut bertentangan dengan ideologi Pancasila yang mengancam bagi bangsa Indonesia dalam penguatan identitas nasional. Dengan demikian, perlu upaya untuk menguatkan  identitas nasional khususnya masyarakat urban yang sudah terpapar dengan budaya pop, melalui: 1) internalisasi nilai-nilai budaya masyarakat dalam berbagai bidang kehidupan; 2) upaya filterisasi berbagai budaya asing yang dianggap membawa nilai-nilai yang bertentangan dengan budaya Indonesia; 3) pendidikan multikultural untuk menguatkan pondasi setiap individu agar tidak mudah tercerabut akar budayanya.