bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECT OF DIFFERENT PHOSPHORUS DOSES ON SEED YIELD AND QUALITY PARAMETERS OF BLACK CUMIN (Nigella sp.)
Authors: GEDİK Osman
Published: June 2022

Phosphorus is an important element that affects the generative development, seed and fruit quality of plants. This study was carried out in the ecological conditions of Kahramanmaras province to determine the effects of different phosphorus doses on the vegetation, yield, and quality characteristics of black cumin. The experiment was carried out in the field of “Field Crops Research and Application Department of Kahramanmaras Sutcu Imam University Faculty of Agriculture” in the winter growing seasons of 2017-18 and 2019-20, according to the split plots in randomized blocks as 3 replications. Two Nigella genotypes, one of which is a registered variety (Cameli variety), and five different P doses (0, 3, 6, 9, 12 kg da-1) were used in the study. According to the research findings, while phosphorus doses did not have a significant effect on plant characteristics such as plant height, number of branches, number of capsules, it was determined that it affected the number of seeds in the capsule and seed yield. The highest number of seeds per capsule (128.23 per capsule-1) was obtained from the highest P (12 kg da-1) application, and the highest seed yield (136.04 kg da-1) was obtained from the 6 kg da-1 P application. Significant differences were observed in doses and genotype × dose interaction in terms of quality characteristics.
Epiphytic bryophyte vegetation of Fagus orientalis trees in Hıdırnebi Plateau (Trabzon, Turkey)
Authors:   Tunceli Vocational School, Munzur University, Alataş Mevlüt , Ezer Tülay ,   Department of Landscape Architecture, Faculty of Architecture, Niğde Ömer Halisdemir University, Erata Hüseyin ,   Bayramiç Vocational School, Çanakkale Onsekiz Mart University, Batan Nevzat ,   Maçka Vocational School, Karadeniz Technical University
Published: June 2022

In this study, the epiphytic bryophyte vegetation of Fagus orientalis forests in Hıdırnebi Plateau (Trabzon, Turkey) was investigated. A total of 34 relevés taken from living tree trunks in the different vegetation periods of 2020 were analysed according to the Braun-Blanquet methodology. As a result of the analyses, the Leskeello nervosae–Pterigynandretum filiformis, Leskeello nervosae–Pterigynandretum filiformis lewinskyetosum rupestris subass. nov., Pseudoleskeello nervosae–Raduletum lindbergianae ass. nov. and Pseudoleskeello nervosae–Raduletum lindbergianae isothecietosum alopecuroidis subass. nov. were described and characterised as a new epiphytic syntaxa. The Leskeello nervosae–Pterigynandretum filiformis is also new to Turkey. In addition, the ecological and floristical characteristics of the syntaxa were evaluated.
Salvia insignis Kudr. (Lamiaceae): current status, rarity, and prospects for conservation in situ
Authors:   Central Siberian Botanical Garden SB RAS, Baikova Elena V. , Turdiboev Obidjon A. ,   Institute of Botany, Academy of Sciences of the Republic of Uzbekistan, Pulatov Sardor ,   Institute of Botany, Academy of Sciences of the Republic of Uzbekistan, Madaminov Farrukhbek ,   Institute of Botany, Academy of Sciences of the Republic of Uzbekistan, Baikov Konstantin S. ,   Central Siberian Botanical Garden SB RAS, Sheludyakova Mariya B. ,   V.L. Komarov Botanical Institute RAS
Published: June 2022

Salvia insignis Kudr. is a rare local endemic growing on the Babatag ridge of Southern Uzbekistan and Tajikistan, between 600 and 1100 m a.s.l. It is an element of specific original flora of variegated outcrops, a typical flora of mountainous Middle Asia. Described in 1937 from the collections of 1887, it was reported as presented in several localities, and only with very few occurrences. Since then, despite the searches by botanists, there have been no collections of herbarium specimens from those sites mentioned in the literature, most likely due to strong environmental human-induced alterations in the landscape. The obtained new data on the distribution and morphology of this species will allow us to develop strategies for its protection in situ and preservation of the gene pool ex situ.
Development of spatial-recreational frame in dense residential areas of megapolis
Authors: Lutchenko Sergey Iv. , Bosak Victoria V.
Published: June 2022

The study analyzes aspects of the impact of high-density development on the periphery of the largest cities. The relevance of the study is dictated by the current situation of large-scale housing construction on the border of St. Petersburg and adjacent districts, which create preconditions for a further reduction in the area of ​​forest areas and an increase in the recreational load on the preserved natural objects. The aim of the study is to develop scientifically grounded recommendations for the functional planning development of the buffer zone between the built-up, subject to development and natural territory in the suburban areas of St. Petersburg in order to preserve the ecological balance of the territory.
Performance Evaluation of Soil Substance Measurement System in Garlic Plant based on Internet of Things with Mesh Topology Network Scenario
Authors: Perdana Doan , Imadudin Muhammad , Bisono Gustommy
Published: June 2022

The high consumption followed by low production makes the government have to import garlic to meet domestic needs every year. To help increase garlic yields, a system designed to facilitate the process of measuring Nitrogen (N), Phosphorus (P), Potassium (K) content on plantation land in realtime using NPK sensor and nodemcu as microcontrollers and peovide the connectivity of realtime information using mesh topology. This system is an Internet of Things (IoT) based network, where internet connectivity is used to exchange information with each other with the objects around it. The result of the design of this system is a device to measure each element of N, P, and K as well as fertility status based on NPK values that have been obtained. And, with the IoT feature and mesh topology built in this device, the measurement data and whether or not the device works can be monitored easily through an android application that has been made on a smartphone. The mesh topology that built in this device is using painlessmesh library where the network built on the system is a true ad-hoc network, meaning that no-planning, central controller, or router is required.  Any system of 1 or more nodes will self-organize into fully functional mesh. We conclude that the accuracy of the measurement data compared to the NPK meter analog (Doctor Plant) is above 90%. Based on the durability test of the device and the system using Xiaomi's power bank of 5000mAh, the device and the system work well for 30 hours without any problems. Moreover, the accuracy of the data measured and uploaded to the database is no error with a 100% compatibility rate.
Computer Forensics: Dark Net Forensic Framework and Tools Used for Digital Evidence Detection
Authors: A. Alotaibi May , A. AlZain Mohammed , Soh Ben , Masud Mehedi , Al-Amri Jehad
Published: June 2022

As the development of technology increases and its use becomes increasingly more widespread, computer crimes grow. Hence, computer forensics research is becoming more crucial in developing good forensic frameworks and digital evidence detection tools to deter more cyber-attacks. In this paper, we explore the science of computer forensics, a dark web forensic framework, and digital evidence detection tools.
Exploring Data Security and Privacy Issues in Internet of Things Based on Five-Layer Architecture
Authors: Patchmuthu Ravi Kumar , Wan Au Thien , Suhaili Wida Susanty
Published: June 2022

Data Security and privacy is one of the serious issues in internet-based computing like cloud computing, mobile computing and Internet of Things (IoT). This security and privacy become manifolded in IoT because of diversified technologies and the interaction of Cyber Physical Systems (CPS) used in IoT. IoTs are being adapted in academics and in many organizations without fully protecting their assets and also without realizing that the traditional security solutions cannot be applied to IoT environment. This paper explores a comprehensive survey of IoT architectures, communication technologies and the security and privacy issues of them for a new researcher in IoT. This paper also suggests methods to thwart the security and privacy issues in the different layers of IoT architecture.
Acknowledge-Based Non-Congestion Estimation: An Indirect Queue Management Approach for Concurrent TCP and UDP-Like Flows
Authors: Sup Luciano Mauro Arley , Moraes Renato Mariz de , Bauchspiess Adolfo
Published: June 2022

This paper presents a new approach for indirect Active Queue Management (indirect AQM) technique called Acknowledge-based Non-Congestion Estimation (ANCE), which employs end-to-end queue management along a network instead to use Explicit Congestion Notification (ECN) bit or to drop packets in the queue. The ANCE performance was compared with Random Early Detection (RED), Control Delay (CoDel), Proportional Integral controller Enhanced (PIE), Explicit Non-Congestion Notification (ENCN), TCP-Jersey and E-DCTCP schemes in a daisychain and in a dumbbell cenario, with TCP flows and UDP-like Networked Control Systems (NCS) flow sharing the same network topology. On the other hand, this paper presents a method for modeling, simulation and verification of communication systems and NCS, using UPPAAL software tool, on which, all network components (channels, routers, transmitters, receivers, plants, and Controllers) were modeled using timed automata making easy a formal verification of the whole modeled system. Simulations and statistical verification show that despite using fewer resources (since ANCE does not need the ECN bit) ANCE presents a very close performance  to ENCN overcoming Drop Tail, RED, CoDel, PIE and E-DCTCP in terms of Integral Time Absolute Error (ITAE) for NCS and fairness for TCP flows. ANCE also attains better performance than RED, PIE, TCP-Jersey and E-DCTCP in terms of throughput for TCP flows.
A Classification of non-Cryptographic Anonymization Techniques Ensuring Privacy in Big Data
Authors: EL OUAZZANI ZAKARIAE , EL BAKKALI HANAN
Published: June 2022

Recently, Big Data processing becomes crucial to most enterprise and government applications due to the fast growth of the collected data. However, this data often includes private personal information that arise new security and privacy concerns. Moreover, it is widely agreed that the sheer scale of big data makes many privacy preserving techniques unavailing. Therefore, in order to ensure privacy in big data, anonymization is suggested as one of the most efficient approaches. In this paper, we will provide a new detailed classification of the most used non-cryptographic anonymization techniques related to big data including generalization and randomization approaches. Besides, the paper evaluates the presented techniques through integrity, confidentiality and credibility criteria. In addition, three relevant anonymization techniques including k-anonymity, l-diversity and t-closeness are tested on an extract of a huge real data set.
Offloading Decisions in a Mobile Edge Computing Node with Time and Energy Constraints
Authors: EL GHMARY Mohamed , CHANYOUR Tarik , HMIMZ Youssef , CHERKAOUI MALKI Mohammed Ouçamah
Published: June 2022

This article describes a simulated annealing based offloading decision with processing time, energy consumption and resource constraints in a Mobile Edge Computing Node. Edge computing mostly deals with mobile devices subject to constraints. Especially because of their limited processing capacity and the availability of their battery, these devices have to offload some of their heavy tasks, which require a lot of calculations. We consider a single mobile device with a list of heavy tasks that can be offloadable. The formulated optimization problem takes into account both the dedicated energy capacity and the total execution time. We proposed a heuristic solution schema. To evaluate our solution, we performed a set of simulation experiments. The results obtained in terms of processing time and energy consumption are very encouraging.
Insuficiencia del Poder Judicial en Chiapas y la Mediación como Alternativa de Justicia
Authors: Martínez Lazcano Alfonso Jaime
Published: June 2022

En el artículo se analiza a los Mecanismos Alternativos de Solución de Controversias, derecho humano consagrado en el artículo 17, párrafo 5, de la Constitución Política de los Estados Unidos Mexicanos, enfocándose especialmente en la mediación, tomando como referencia el caso de Chiapas que ante la crisis por la que atraviesa la administración de justicia hace pensar en este mecanismo como un método de solución de conflictos de manera pronta y eficaz. Para llegar a tal conclusión se hará uso del método analítico y el manejo de fuentes documentales.
Sesgos Implícitos y Juicios por Jurados
Authors: Villanueva Carlos M.
Published: June 2022

En las últimas décadas ha existido un creciente interés por la forma en las cuales los sesgos implícitos pueden jugar un papel importante en las decisiones judiciales discriminatorias en contra de ciertos grupos vulnerables, ya sean en virtud de la raza, el género, la condición social, religiosa, etc. En los estudios se trata de identificar la forma en que estos estos sesgos funcionan sino también los mecanismos a través de los cuales pueden mitigarse, obstaculizarse la incidencia de los mismos en la decisión jurisdiccional. En el presente trabajo se inscribe dentro de esta línea de investigación centrándose en los juicios por jurados, analizando la forma en que la sesgos pueden estar presentes en su decisión así también como la identificación y descripción de los mecanismos procesales con los que contaría el diseño de esta forma de juzgamiento, para el control de los sesgos implícitos y las medidas que pueden tomarse a los fines de que dichos mecanismos cumplan de mejorar manera función de alcanzar una decisión imparcial.
Effects of open adductor tenotomy and adductor muscle botulinum toxin A injection on the hip instability in spastic type cerebral palsy
Authors: ASFUROĞLU Zeynel Mert , GÜNEL Kemal Gökhan , ÖMEROĞLU Hakan
Published: June 2022

Purpose: We aimed to evaluate the clinical and radiographic outcomes of hip instability in children with spastic-type Cerebral Palsy (CP) who had undergone open Adductor Tenotomy (AT) or received Botulinum Toxin-A (BTX-A) injections to the hip adductor muscles .

Materials and Methods: Maximum Hip Abduction Angles (MHAA) with the knees and hips in extension were measured preoperatively and the latest clinical findings of all patients in the AT and BTX-A groups were recorded. Reimers’ Migration Percentage (RMP) was measured as the radiographic assessment in the AT group.

Results: There were 30 patients (mean age: 8.3 years) in the AT Group and 25 (mean age: 5.9 years) in the BTX-A Group whose clinical and radiographic data were available. The mean follow-up period in the AT Group was 29.6 months. In the AT Group, the mean MHAA before surgery and at the last assessment were 21.20 and 37.10 respectively. In the BTX-A Group, the mean MHAA before the injection and at the latest assessment were 25.30 and 34.20 respectively. The change in the mean MHAA in the AT Group was 16.20 and 8.80 in the BTX-A Group. In the AT Group, the preoperative RMP was 28.2% and the latest RMP was 22.2%.

Conclusion: AT and BTX-A injections significantly improved hip abduction angles. However, AT provided better clinical improvement and considerable radiographic correction in pediatric patients with spastic-type CP and hip instability.
Humerus cisim kırıklarında minimal invaziv perkütan plak osteosentezi (MIPPO)
Authors: KUNDAKÇI Buğra , BİÇER Ömer , HURİ Gazi , TEKİN Mustafa , BAĞIR Melih , DEVECİ Mehmet Ali , MİRİOĞLU Akif
Published: June 2022

Amaç: Kliniğimizde minimal invaziv perkütan plak osteosentezi (MIPPO) ile tedavi edilen humerus cisim kırıklarının radyolojik ve fonksiyonel sonuçlarının değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntem: MIPPO ile tedavi edilen 20 hastanın 21 humerus cisim kırığına ait verileri retrospektif olarak değerlendirildi. Hastaların demografik verileri, yaralanma şekilleri, AO sınıflaması ve bölgesine göre kırık sınıflaması, sigara kullanımı, radial sinir yaralanması kaydedildi. Radyografik olarak 6. ayda kaynama durumu ve dizilim değerlendirildi. Hastaların son kontrollerinde omuz ve dirsek hareket açıklığı ile objektif, Amerikan Omuz ve Dirsek Derneği (ASES) skoru, California Üniversitesi Los Angeles (UCLA) skoru, Mayo dirsek performans indeksi (MEPI), Kol Omuz El Engellilik (DASH) skoru ve Constant omuz skoru ile subjektif değerlendirme yapıldı.

Bulgular: Hastaların ortalama omuz fleksiyonu 169,5°±26,4°, abdüksiyonu 169,5°±26,4° idi. Ortalama dirsek hareket arkı 131,4°±19,8° bulundu. Ortalama ASES ve UCLA skorları sırasıyla 88,5±16,4 ve 32,1±5,2, MEPI ve DASH skoru sırasıyla 93,1±11,3 ve 11,8±20,0, ortalama Constant skoru 9,1±15,3 bulundu. İki hastada 6. ayda kaynamama gözlendi.

Sonuç: MIPPO yöntemi humerus cisim kırıklarının tedavisinde; minimal yumuşak doku hasarı, korunmuş omuz ve dirsek fonksiyonları ile başarılı bir tekniktir.
Rituximab treatment in children with difficult-to-treat nephrotic syndrome
Authors: PARMAKSIZ Gönül
Published: June 2022

Purpose: Rituximab (RTX) has been offered as rescue therapy for patients with difficult-to-treat nephrotic syndrome (frequent relapsing, steroid-dependent and steroid resistant). We aimed to assess the efficacy and long-term outcomes of RTX treatment in children with difficult nephrotic syndrome and shared our experiences

Materials and Methods: Medical records of children with difficult nephrotic syndrome who were treated with RTX were retrospectively evaluated. The relapse-free survival rate at 12 month and monitoring of B-cell depletion were assessed.

Results: In the study included 20 children of which 8 had steroid-dependent (SDNS), 6 had frequent relapsing (FRNS), and 6 had steroid-resistant nephrotic syndrome (SRNS). The median number of relapses at 1 year before and after treatment in FRNS/SDNS patients receiving RTX treatment were compared. The median number of relapses decreased from 2 (1-4) to 0 (0-1) times/year. The mean duration of the follow-up period after RTX treatment was 23 (12-59) months, and 8 patients developed relapse. Repeated doses of RTX were administered to 5 patients who relapsed after RTX treatment. In these patients, CD19+B cells re-emerged during remission, while depletion of memory B-cells remained.

Conclusion: The RTX treatment prolonged the remission time in FRNS/SDNS patients, but it was ineffective in SRNS patients. It was determined that the RTX doses can be repeated to maintain remission in these patients, and the best memory B-cell counts can help in timing the repeat doses.
Fare ve Ratlarda Yapay Tatlandırıcıların Bağırsak Mikrobiyotası Üzerine Etkisi: Randomize Kontrollü Çalışmaların Sistematik Derlemesi
Authors: DUMAN Emre , KESER Alev , YILMAZ IŞIKHAN Selen
Published: June 2022

Yapay tatlandırıcıların bağırsak mikrobiyotası üzerine etkisini inceleyen fare ve ratlarda yapılmış randomize kontrollü çalışmaların sistematik olarak incelenmesidir. PRISMA bildirgesi rehber alınarak PubMed, Web of Science, EBSCOHost ve Google Akademik olmak üzere 4 veri tabanı kullanılmış, 1 Ocak 2000-31 Aralık 2020 tarihleri arasında yayınlanan tüm rat ve fareler ile ilgili randomize kontrollü çalışmaları belirlemek için sistematik bir tarama yapılmıştır. Yapay tatlandırıcı olarak advantam, asesülfam-K, aspartam, neotam, sakkarin, siklamat ve sükraloz kullanılan çalışmalar dahil edilmiştir. İlk tarama sonucunda fare ve ratlar üzerinde yapılan toplam 901 çalışma elde edilmiştir. Çalışmanın amacına ve dahil etme kriterlerine uygun 11 randomize kontrollü çalışma sistematik derlemeye dahil edilmiştir. Çalışmalardan iki tanesi ratlar üzerinde, dokuz tanesi ise fareler üzerinde gerçekleştirilmiştir. Dahil edilme kriterlerini karşılayan advantam ve siklamat ile yapılmış çalışmaya literatürde rastlanmamıştır. Örneklem sayısının az olması nedeniyle meta-analiz yapılamamıştır. Fare ve ratlarda yapay tatlandırıcıların bağırsak mikrobiyotası üzerine etkisi olmakla birlikte etkisine yönelik net bir kanıt ortaya konulamamıştır. Bağırsak mikrobiyomundaki değişikliklerin insan sağlığını nasıl etkilediğinin araştırılması önemlidir ve bu nedenle yapay tatlandırıcı tüketiminin mikrobiyota üzerindeki etkisini değerlendiren randomize kontrollü klinik çalışmaların sayısının artması önemli bir gerekliliktir.
Mikroplastiklerin Canlılara Etkileri
Authors: PEKMEZEKMEK Ayper
Published: June 2022

Okyanus ve denizlerimiz yaklaşık 60 yıldan beri plastiklerle kirlenmektedir. Tüm dünyada plastik tüketiminin artması, plastiklerin bozunmadan yüzlerce yıl çevrede kalması, plastiklerin daha küçük parçalara ayrışması, deniz besin zincirinin tüm seviyelerindeki organizmalarda tespit edilmesi ve insanların gıda yoluyla mikroplastiklere maruz kalma olasılığı bu konudaki farkındalığı her geçen gün artırmaktadır. Mikroplastikler ve nanoplastiklerin devreye girmesiyle özellikle 2010 yılından beri bilim adamları sulardaki bu kirlilikle ilgili çalışma yapmaya başlamışlardır. Ortak görüş bu kirlilik türünün çevre üzerine etkisinin daha da büyüyeceği ve canlılara zarar vereceği şeklindedir.
Kök Hücre; Tanımı ve Genel Özellikleri, Kullanım Alanları, Tarihi, Yüzey Belirteçleri
Authors: AVCI Murat
Published: June 2022

Yüzyılı aşkın geçmişi olan kök hücreler, günümüzde birçok hastalığın tedavisi için araştırma konusu olmaya devam etmektedir. Rejeneratif tıbbın da ilgi odağı olan kök hücreler; uzun süre bölünebilme, kendini yenileme ve farklılaşma özelliklerine sahiptir. Kök hücrelerde simetrik ve asimetrik hücre bölünmesi olmak üzere iki farklı bölünme şekli görülmektedir. Kök hücreler telomerlerini tamamlayabildiği için normal hücrelerden farklı olarak uzun süre bölünebilen hücrelerdir. Kök hücrelerin tespiti için kullanılan yüzey belirteçlerin çeşitliliği ve ortak belirteçlerin varlığı, dokuya özgü kanser kök hücreler içinde geçerlidir. Bu derleme çalışmasındaki amaç; kök hücrelerin tanımı ve genel özellikleri, kullanım alanları, tarihi ve yüzey belirteçleri hakkındaki bilgileri ana başlıklar altında bir araya getirmek ve araştırmacıların kullanımına sunmaktır.
Nocturnal Noninvasive Positive Pressure Ventilation in Stable Severe Chronic Obstructive Pulmonary Disease
Authors: ÖZKAN KUŞCU Özlem , ERGENOĞLU Pınar
Published: June 2022

Chronic Obstructive Pulmonary Disease is characterized as a progressive and irreversible inflammatory response in the airways and alveoli because of exposure to noxious particles or gases. Excessive inflammation causes progressive, persistent, and not fully reversible structural changes and airflow limitation. Although COPD is a significant public health problem, diagnosis and treatment stages need to be improved.Nocturnal Noninvasive Positive Pressure Ventilation is one of the treatment modalities of choice for COPD exacerbation, and the role and benefits of NPPV in COPD exacerbation are well defined, but the use of nocturnal NPPV on stable severe COPD individuals is controversial, and the evidence is not sufficient yet. This review evaluates the effects of nocturnal NPPV on stable COPD patients.
Kanser Kök Hücrelerine Güncel Yaklaşım
Authors: SAPMAZ ERÇAKALLI Tuğçe , POLAT Sait
Published: June 2022

Kanser Kök Hücreleri (KaKH), normal kök hücreler gibi kendi kendini yenileme ve farklılaşma yeteneğine sahip hücreler olup meme, beyin, akciğer, prostat, testis, over, yemek borusu, kolon, karaciğer gibi birçok dokuda bulunur. Kökenleri henüz keşfedilmemiştir, ancak bu konuda bir dizi hipotez öne sürülmüştür. KaKH tümörün başlangıcından sorumlu ve tümör dokusundaki çok sayıda farklılaşmış hücre topluluğunu oluşturan hücrelerdir. Her bir kanserin kök hücresini tanımlayan biyobelirteçler vardır. KaKH’lerin ve normal kök hücrelerin kendi kendini yenileme ve farklılaşmasında aynı özgü sinyal iletim sistemleri rol oynamaktadır. Fakat KaKH’lerde bu sinyal iletim sistemlerinin düzenlenmesi değişmektedir. KaKH'leri sadece kanserin yaratılmasında değil, evriminde, metastazında ve geç dönemde yeniden ortaya çıkmasında da rol oynamaktadır. MikroRNA'lar, Wnt/β-catenin, Notch ve Hedgehog gibi sinyal yolaklarından oluşan bir düzenleme ağı KaKH özelliklerini kontrol eder. KaKH'leri kanser tedavisinde, konvansiyonel kemoterapi ve radyasyon tedavisine karşı dirençte rol oynarak, kanser metastazının kökeni olarak değerlendirilebilir. KaKH'leri yeni kanser önleyici ilaç keşfi için tedavi protokollerinde hedef haline gelmiştir. Gelecekteki çalışmalar kanserin tedavisi için KaKH’leri hedef alan tedavilerin geliştirilmesine öncülük edecektir.
Effect of eradication treatment for Helicobacter pylori on complete blood count and inflammatory parameters
Authors: ALANLI Recep , KÜÇÜKAY Murat Bülent
Published: June 2022

Background and aims: Previously Helicobacter pylori (H. Pylori) infection was held responsible for changes in complete blood count and inflammatory parameters. But changes in these parameters after eradication treatment was not entirely evaluated. This study was designed to evaluate the effect of eradication threatment for H. pylori infection on inflammatory markers and complete blood count parameters. Materials and method: This single center observational study enrolled participants who came to internal medicine outpatient clinics because of dyspeptic complaints and who were diagnosed to have H. pylori infection after endoscopic evaluation, between July 2021 and January 2022. Participants who were tested negative for H. pylori stool antigen test eight weeks after eradication treatment were included. Complete blood count and infammatory parameters before and after eradication treatment were compared. Results: Mean participant age was 43.84±12.59 years. There were significant decreases in C-reactive protein (CRP), platelet to lymphocyte ratio (PLR) and neutrophile to lymphocyte ratio (NLR) after eradication. Changes in platelet counts and mean platelet volumes (MPV) were insignificant. Conclusion: CRP, PLR and NLR were significantly lower after eradication for H. pylori. These parameters may be useful, simple, available and non-invasive tests that may be used in evaluation of eradication treatment for H. pylori.
Sağlık eğitimi alan üniversite öğrencilerinde COVID-19 pandemi sürecinde değişen beslenme ve hijyen alışkanlıkları ile koronavirüs korku düzeyleri arasındaki ilişki
Authors: KAYA Gülsüm , TRABZON Şeyma , ALTINDİŞ Selma , ALACAHAN Ruveyda
Published: June 2022

Amaç: Bu çalışmada COVID-19 pandemi döneminde üniversite öğrencilerinin beslenme ve hijyen alışkanlıklarında değişim ile COVID-19 korku düzeylerini belirlemek amacıyla yapılmıştır.

Yöntem: Çalışma, Mayıs-Haziran 2020 arasında Sakarya Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu ve Sağlık Bilimleri Üniversitesi Hamidiye Sağlık Meslek Yüksek Okulu’nda öğrenim gören ve çalışmaya katılmayı kabul eden öğrencilerle online anket aracılığıyla yapılmıştır. Veriler SPSS 21 programında analiz edildi, p
Modeling the tendon suture with its isolation to demonstrate primary regeneration of the junction area
Authors:   Gomel Regional Clinical Hospital, Gomel, Belarus, Zenchenko A.V. , Tarasenko S.V. ,   Gomel Regional Clinical Bureau of Pathological Anatomy, Gomel, Belarus
Published: June 2022

Introduction Functional recovery of the finger flexor tendon after surgical treatment is a problem due to formation of unavoidable blocking adhesions. For prevention of the adhesions, the mechanical separation of the sliding surfaces of the tendon and the wall of the fibro-osseous canal with a polymer tube was proposed. However, despite good clinical results, it is not possible to morphologically confirm the healing of the suture zone after such an intervention. Objective To present an experimental model and technique of surgical intervention on the calcaneal tendon of laboratory animals for isolation and blocking with a polymeric tube, longitudinally cut, for obtaining and studying the regenerate in the suture site Materials and methods In an experiment under inhalation anesthesia with Isoflurane on both hind paws of 10 laboratory Wistar rats, the tendon suture was simulated with blocking and isolation of the tendon suture (n = 14) and the control operation without isolation (n = 6). The tendons were excised three weeks post-surgery, and the appearance and histological picture of the regenerates in the suture zone were examined. Results The surgery model with isolation of the suture site on the calcaneal tendons of rats reproduces well and adequately simulates the operation on the human hand tendons. The morphology of the obtained regenerates demonstrates the restoration of continuity with the formation of tendon-like tissue at the junction. In the experiment, subtotal isolation did not lead to tendon necrosis, but slowed down the healing of the suture zone. The tube prevented the formation of adhesions and maintained tendon nutrition through the fissure space. Conclusion Modeling of the operation of tendon suture on the rat calcaneal tendon with its isolation provides material for demonstration the primary tendon regeneration in vivo. Regeneration of the suture site during subtotal isolation slows down and occurs due to the cells of the tendon itself.
A new surgical technique for the treatment of recurrent patellar dislocation: review of primary results
Authors:   Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Uzbekistan, Irismetov M.E. , Rasulov M.R. ,   Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Uzbekistan, Khuzhanazarov I.E. ,   Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Uzbekistan,   Tashkent Medical Academy, Tashkent, Uzbekistan
Published: June 2022

Introduction Surgical options used to treat recurrent patellar dislocations (RPD) in different countries include release of the lateral tendon retinaculum, tibia medialization, fixation of an autologous graft to the hip, transplantation of the ipsilateral gracilis tendon and medial patellofemoral ligament reconstruction. The methods may not completely eliminate the dislocation to ensure patellar stability and we undertook to develop a new surgical technique. The objective was to identify advantages and disadvantages of the new methodology for the treatment of RPD through comparative analysis. Material and methods 28 patients with RPD of varying degrees treated in the Department of Sports Trauma, State Institution "RSNPMCTO" the Ministry of Health of the Republic of Uzbekistan between 2015 and 2018 were reviewed. Dislocations were graded as average (grade 2; n = 3, 10.7 %) and grade 3 (n = 25; 89.3 %). Five (17.8%) of 28 patients had impaired m. vastus medialis and 23 (82.2 %) were diagnosed with impairment and defect of the retinaculum patella mediale. The patients underwent physical, laboratory, radiological and instrumentation (ultrasound, magnetic resonance imaging, diagnostic arthroscopy) examinations. Results Arthroscopic procedure of the knee joint with autoplasty patellar stabilization using the m. gracilis tendon and a biodegradable screw resulted in good outcomes (n = 27; 96.4 %) and a fair result in a patient (3.6 %) with grade 3 RPD due to synovitis, bursitis and pain in the knee joint; no poor results reported. Conclusion The patients could completely regain the limb functions through arthroscopic procedure of the knee joint with autoplasty patellar stabilization using the m. gracilis tendon and a biodegradable screw, optimization of surgical treatment strategy with regard to severity of displacement and injury to the soft tissues at the medial aspect of the patella.
Comparative analysis of outcomes of multiplanar static forefoot deformity accompanied by flexible second mallet toe deformity treated with various techniques
Authors:   City Clinical Hospital No. 3 of Krasnodar, Krasnodar, Russian Federation, Cherevtsov V.N. , Blazhenko A.N. ,   Kuban State Medical University, Krasnodar, Russian Federation, Bogdanov S.B. ,   Kuban State Medical University, Krasnodar, Russian Federation, Kireev V.S. ,   Peoples’ Friendship University of Russia, Moscow, Russian Federation,   City Clinical Hospital. S.S. Yudina, Moscow, Russian Federation, Gorokhov A.V. ,   Republican Children's Clinical Hospital, Simferopol, Republic of Crimea, Russian Federation
Published: June 2022

Introduction Complicated multiplanar static forefoot deformities can occur at any age ranging 72 % to 80 % in older patients significantly reducing the quality of life. The results of treatment of flexible mallet toe deformity of "smaller" toes cannot be considered satisfactory with floating toe syndrome reported in 20–54 % of cases. The objective of the study was to evaluate the effectiveness of the original technology offered for the treatment of complicated multiplanar static forefoot deformities which differs from traditional methods by the way the plantar plate of "smaller" toes is restored. Material and methods The study included 43 patients who were divided into two groups depending on the type of reconstruction performed. Long-term outcomes were evaluated at 12 months of surgery using AOFAS questionnaire, radiology, VAS and the Hamilton-Thompson metatarsophalangeal “drawer test”. Results Conventional surgical technology applied for patients of group A and group B allowed reduction of the M1-M2 angle by 7.2 ± 1.1 degrees and visual elimination of the the second mallet toe deformity in all cases. There was no floating toe noted among patients of group B, and the deformity was defected in 5 (27.8 %) patients of group A; contracture of the second metatarsophalangeal joint diagnosed in 1 (4.0 %) patient of group B and in 8 (44.4 %) cases of group A. Conclusion The flexible mallet toe deformity of the second toe treated with the technique we developed allowed us to avoid the development of floating toe syndrome, contracture of the second metatarsophalangeal joint and improve the quality of life by 28.7 ± 2.4 AOFAS score.
MSCT semiotics of diabetic osteoarthropathy complicated by chronic osteomyelitis
Authors:   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Diachkova G.V. , Sudnitsyn A.S. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Klushin N.M. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Diachkov К.А. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Larionova T.A. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Khieva E.V. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation
Published: June 2022

Background Conventional radiography, magnetic resonance imaging, nuclear medicine scintigraphy are the imaging techniques currently in use for the evaluation of diabetic neuroosteoarthropathy (DN) with computed tomography being not commonly employed even for cases complicated by chronic osteomyelitis. The objective was to explore MSCT-semiotics of anatomical and radiomorphological changes in foot bones in patients with DN complicated by chronic osteomyelitis (CO) to determine most common manifestations of CO in diabetic foot. Material and methods Single-centre retrospective study. A series of cases. Preoperative radiological findings, MSCT (multislice computed tomography) were examined in 14 patients with DN complicated by chronic osteomyelitis. Results The patients showed impaired structure of the cancellous bone of various severity depending on the nature and localization of foot bone destruction. Overall bone density was higher in cancellous bone of the distal tibia, talus, calcaneus with the local density ranging within significant limits and was maximum at some points of the subchondral tibia and talus and minimum in the intertrabecular areas of the calcaneus and the distal tibia. MSCT scans showed medial calcinosis of the arteries in 5 (35.7 %) from 14 patients. Conclusion MSCT as one of the most objective method for the qualitative and quantitative assessment of the bone is practical for identifying anatomical and topographic relationships of the foot bones and the ankle joint to facilitate reconstructions in three planes and VRT, which is important for assessing the foot in patients with DN complicated by chronic osteomyelitis. The technique allows measurement of the foot bone density in Hounsfield units determining the severity of osteoporosis, the extent of architectonics impairment to facilitate preoperative planning.
Changes in the antioxidant/prooxidant balance in patients with acquired shortening of the lower leg bones at the stages of the Ilizarov lengthening procedure
Authors:   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Aranovich A.M. , Stogov M.V. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Tushina N.V. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Kireeva E.A. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation
Published: June 2022

Introduction Optimization of the conditions of distraction osteogenesis using the method of G.A. Ilizarov remains an important challenge to ensure a reduction in the number of complications and an increase in the effectiveness of this technology. The aim of the study was to study the changes in the antioxidant/prooxidant balance in patients with acquired shortening of the lower leg bones at the stages of the Ilizarov lengthening procedure. Methods The antioxidant/prooxidant status was studied in 12 patients with shortening of one of the lower legs resulting from hematogenous osteomyelitis (group 1) and in 13 patients with post-traumatic shortening of one of the lower legs (group 2). The level of peroxidation products, the activity of superoxide dismutase and vitamins E and A in the blood of these patients were assessed in the dynamics of monofocal bone lengthening using the Ilizarov method. Results It was found that in patients with acquired shortening of the shin bones, regardless of the shortening etiology, during surgical lengthening, an increase in the level of peroxidation products in the blood was observed with a decrease in the level of vitamin E and an increase in superoxide dismutase activity. Discussion The data obtained, together with the current findings from fundamental research, allow us to note that the use of antioxidants (AOs) in patients undergoing segment length correction using the Ilizarov technology is possible from two positions. 1. The positive effect of AOs in terms of stimulation of distraction osteogenesis has been proven. 2. AOs have a systemic effect in the regulation of the recovery processes in the paraosseous tissues of the limb segment under lengthening. Conclusion Peroxidation is activated in the course of surgical lengthening of the lower leg bones in patients with acquired shortenings, regardless of the shortening etiology. The use of antioxidants in such patients can specifically inhibit peroxidation, thereby reducing the risk of provoking bone formation disorders.
Indicators of the kinetics of locomotor stereotypes in healthy children in different speed ranges of movement
Authors:   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Dolganova T.I. ,   Kurgan State University, Kurgan, Russian Federation, Popkov D.A. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Dolganov D.V. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Chibirov G.M. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation
Published: June 2022

Purpose To determine the normative values of the kinetic parameters of gait in healthy children in different speed ranges of movement. Materials and methods Locomotor profile assessment by video gait analysis (CGA) was performed on an outpatient basis in 27 children (54 limbs), aged 10–13 years. The following variables were used and processed: peak negative hip, knee and ankle power (W/kg) (relaxation); peak positive power of the hip, knee and ankle (support push) joints (W/kg) (generation); the total positive and total negative power was calculated(for the hip, knee and ankle joints); total peak power; net peak power values and overall mechanical efficiency. Kinetics indicators were generalized according to the ranges of ranking of the absolute walking speed (km/h), taking into account the weight of patients. Quantitative characteristics are presented in the table as a median, percentile range of distribution of values (25÷75 %) and the number of observations (n) equal to the number of limbs. Results The normative kinetic parameters of gait are presented at a speed of movement in the range from 1.1 to 5.0 km/h in healthy children aged 10–13 years. A strong correlation was found between the values of the power of the reference shock during the formation of the reciprocal inhibition reflex of the shin sprain and the speed parameters of movement (r = -0.925, n = 142 and p < 0.001). To change the speed of movement, the motor locomotor stereotype was changed with the redistribution of the load from one joint muscle to another. If the share of the contribution of the power of the muscles of the hip joint increased, on average, by 10.8 %, and of the knee joint – by 15.3 %, then the share of the contribution of the ankle joint decreased by 16.8 %. Discussion In locomotor stereotypes in the examined children, a significant positive correlation was found between walking speed and the total (r = 0.907, n = 104) and useful peak power (r = 0.475, n = 104) of the joint muscles, while the maximum median values of the useful total peak the power of all joint muscles was recorded at a speed of movement in the range from 3.1 to 4.0 km/h.
Current aspects of preoperative planning and selection of surgical techniques for revision anterior cruciate ligament reconstruction
Authors:   Vreden National Medical Research Center of Traumatology and Orthopaedics, St. Petersburg, Russian Federation, Saprykin A.S. , Bantser S.A. ,   Vreden National Medical Research Center of Traumatology and Orthopaedics, St. Petersburg, Russian Federation, Rybinin M.V. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint Petersburg, Russian Federation, Kornilov N.N. ,   Vreden National Medical Research Center of Traumatology and Orthopaedics, St. Petersburg, Russian Federation
Published: June 2022

Introduction Reconstruction of the anterior cruciate ligament (ACL) is one of the most common surgical procedures around the knee. Despite good long-term outcomes in general, thousands of revisions after ACL reconstruction are performed annually in the world due to graft failures, repeated injuries, technical errors, disorders in ligamentization process or inadequate rehabilitation. The aim of the study was to evaluate the current evidence and describe the relevant clinical features of planning and performing revision ACL reconstruction. Materials and methods A search was conducted for English- and Russian-language publications in the electronic databases PubMed and e-LIBRARY for the period from 2000 to 2020 using the keywords: anterior cruciate ligament, ACL, revision, re-reconstruction, re-rupture. Among 572 publications, 107 corresponded to the study topic. Based on the inclusion criteria (more than 50 reported cases; follow-up more than 2 years; homogeneous groups of patients; assessment with knee function scores; application of various imaging options), 31 articles were included in this review. There were no Russian studies that met the above-mentioned criteria. Results and discussion The analysis of the literature identified four clinically relevant features in the treatment of patients with failures of ACL reconstruction: criteria and principles for the implementation of a one- or two-stage approach; additional features of the revision ACL reconstruction; determination of the optimal graft type. Conclusion Most of the revision ACL reconstructions can be performed at one stage, combined with bone grafting if needed. For a successful treatment outcome, in some cases, correction of frontal and sagittal deformity of the lower limb, management of the injury to other knee joint stabilizers, to cartilage or menisci is required. Surgeons’ preferences in the choice of plastic material has shifted to autografts with bone blocks, or allografts, especially if reconstruction of several stabilizers is necessary.
Comparitive evaluation of antimicrobial effectiveness of silver oxide coatings on different types of ceramic brackets against Streptococcus mutans
Authors: Goud S. V. Ramesh , Sigamani K. Raja , Bhaskar  , Kumaran Kurinchi , Arafat Mohammed , Duvvuri S.N Reddy
Published: June 2022

The historical aspect of nanotechnology dates back to 600 BC. Taniguchi was the first to use the term nanotechnology in 1974, originating from a Greek word meaning “dwarf”. Nanotechnology when combined with dentistry and medicine created an interdisciplinary field i.e., nanodentistry and nanomedicine and this combination gets engineers, chemists, physicians on a single platform having various applications in detection, imaging and drug delivery devices.With respect to orthodontics, the nanoparticle coated archwires, adhesives, temporary anchorage devices, brackets, orthodontic wires with shape memory and biofilm control features have been applied. Silver nanoparticles are combined with different accessory orthodontic materials which results in the addition of more antimicrobial properties which inturn decreases the biofilm formation and maintain better oral health. Antibacterial effectiveness of nanosilver coated materials has been shown with and without the release of nanosilver ions in in vitro studies. In addition, long-term inhibitory effects against S.mutans have been found while no nanosilver ions were released.

30 MBT 0.022’’ monocrystalline ceramic brackets and 30 MBT 0.022’’ polycrystalline ceramic brackets (Metro Orthodontics) which are randomly divided into 4 groups: 2 control groups (group-1=15 uncoated monocrystalline and group-2=15 uncoated polycrystalline) and 2 experimental groups (group-3=15 silver oxide coated monocrystalline and group-4=15 silver oxide coated polycrystalline).

S.mutans counts were significantly less in the experimental groups than control groups.

Silver oxide coatings on ceramic brackets reduced the colony forming units of S. mutans. Both monocrystalline and polycrystalline coated brackets showed reduced number of colony forming units than their control groups.