bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioinformatics approach to identify the hub gene associated with COVID‐19 and idiopathic pulmonary fibrosis
Authors: Shi Wenchao , Li Tinghui , Li Huiwen , Ren Juan , Lv Meiyu , Wang Qi , He Yaowu , Yu Yao , Liu Lijie , Jin Shoude , Chen Hong
Published: October 2023

The coronavirus disease 2019 (COVID‐19) has developed into a global health crisis. Pulmonary fibrosis, as one of the complications of SARS‐CoV‐2 infection, deserves attention. As COVID‐19 is a new clinical entity that is constantly evolving, and many aspects of disease are remain unknown. The datasets of COVID‐19 and idiopathic pulmonary fibrosis were obtained from the Gene Expression Omnibus. The hub genes were screened out using the Random Forest (RF) algorithm depending on the severity of patients with COVID‐19. A risk prediction model was developed to assess the prognosis of patients infected with SARS‐CoV‐2, which was evaluated by another dataset. Six genes (named NELL2, GPR183, S100A8, ALPL, CD177, and IL1R2) may be associated with the development of PF in patients with severe SARS‐CoV‐2 infection. S100A8 is thought to be an important target gene that is closely associated with COVID‐19 and pulmonary fibrosis. Construction of a neural network model was successfully predicted the prognosis of patients with COVID‐19. With the increasing availability of COVID‐19 datasets, bioinformatic methods can provide possible predictive targets for the diagnosis, treatment, and prognosis of the disease and show intervention directions for the development of clinical drugs and vaccines.
Mg II h&k fine structure prominence modelling and the consequences for observations
Authors: Peat A. W. , Labrosse N. , Gouttebroze P.
Published: October 2023

Aims. Using 2D Mg II h&k solar prominence modelling, our aim is to understand the formation of complex line profiles and how these are seen by the Interface Region Imaging Spectrograph (IRIS). Additionally, we see how the properties of these simulated observations are interpreted through the use of traditional 1D prominence modelling.

Methods. We used a cylindrical non-local thermodynamic equilibrium (NLTE) 2D complete redistribution (CRD) code to generate a set of cylindrical prominence strands, which we stacked behind each other to produce complex line profiles. Then, with the use of the point spread functions (PSFs) of IRIS, we were able to predict how IRIS would observe these line profiles. We then used the 1D NLTE code PROM in combination with the Cross Root Mean Square method (xRMS) to find the properties recovered by traditional 1D prominence modelling.

Results. Velocities of magnitude lower than 10 km s−1 are sufficient to produce asymmetries in the Mg II h&k lines. However, convolution of these with the PSFs of IRIS obscures this detail and returns standard looking single peaks. By increasing the velocities by a factor of three, we recover asymmetric profiles even after this convolution. The properties recovered by xRMS appear adequate at first, but the line profiles chosen to fit these profiles do not satisfactorily represent the line profiles. This is likely due to the large line width of the simulated profiles.

Conclusions. Asymmetries can be introduced by multithread models with independent Doppler velocities. The large line width created by these models makes it difficult for traditional 1D forward modelling to find good matches. This may also demonstrate degeneracies in the solution recovered by single-species 1D modelling.
Unravelling the post-collision properties of the Cartwheel galaxy: A MUSE exploration of its bar and inner region
Authors: Mondal Chayan , Barway Sudhanshu
Published: October 2023

Aims. We aim to investigate the characteristics of the bar and inner disc in the collisional ring galaxy Cartwheel.

Methods. We used integral field unit (IFU) observations from the Multi-Unit Spectroscopic Explorer (MUSE) of the Very Large Telescope (VLT) to investigate the stellar kinematics, age, and nature of ionised gas in the inner region of the Cartwheel galaxy. We produced stellar line of sight velocity (V), velocity dispersion (σ), h3 velocity moment, stellar population age, and emission-line maps of the galaxy using the Galaxy IFU Spectroscopy Tool (GIST) pipeline.

Results. The observed nature of the intensity, V, and σ profiles together support the existence of a stellar bar, as earlier revealed from near-infrared (NIR) Ks-band imaging. A weak correlation between V/σ and h3 is found within the bar radius, providing more kinematic evidence for a stellar bar that survived the drop-through collision. The overall weak anti-correlation between V/σ and h3 in the disc implies that the stellar orbits in the disc are less stable, which might be due to the impact of the collision. The mass-weighted age map of the galaxy shows that the stellar populations in the bar region are relatively old, with an increasing gradient from the bar edge to the centre, further evidence that the bar was present before the galaxy underwent collision. Using a BPT diagram, we analysed a central unresolved source detected earlier with NIR imaging and do not find evidence of an active galactic nucleus. Our findings signify the preservation of the pre-collisional structures in the inner region of the Cartwheel, an important point to note when attempting to determine the evolution of collisional galaxy systems, particularly when investigating pre-collisional central regions in theoretical studies.
Possibilities of solving two-dimensional hydrodynamic problems on the basis of the non-divergent form of recording the transport and conservation equations
Authors: Salokhiddinov Abdulkhakim , Savitsky Andre , Radkevich Maria , Ashirova Olga
Published: October 2023

Existing and applied in practice to solve the aerodynamics and hydrodynamics problems finite-difference schemes ensure that the laws of conservation of matter and energy only in limited configurations of velocity fields. In other cases, there are balance errors, which are currently accepted as the norm, and special algorithms of recalculation have been developed to reduce them. Additional calculations are labor-intensive, and when solving small-scale problems, balance errors can completely distort the calculation results. This article attempts to solve two-dimensional hydrodynamic problems using a new finite-difference computational scheme previously developed by the authors, based on the non-divergent form of recording the transfer and conservation equations. Initially, the scheme was developed and tested in one-dimensional space and showed complete conservativity, stability, transportability and adequacy. To solve two-dimensional problems, a transformation of the proposed scheme was performed. The solution of the test problems and comparison with the calculation results of other known schemes showed that in two-dimensional space the proposed scheme surpasses the results obtained by the HEC-RAS and Courant-Isakson-Reese schemes. The proposed scheme makes it possible to use the maximum possible time steps in the calculations, and the resulting scheme viscosity has minimal values. This property of the scheme makes it possible to apply it to solve small-scale aerodynamic and hydrodynamic problems.
Development of Balloon Biogas Plant for Small Farmers
Authors: Bodhe Arvind , Dethe Pragati , Sethi Muneesh , Deshmukh Dheeraj , Vishakarma Anoop Kumar , Chauhan Avnish
Published: October 2023

Biogas plants are a sustainable and environmentally friendly way of generating energy from organic waste materials such as animal manure, crop residues, and food waste. In addition to producing biogas, these plants also generate nutrient-rich bio-slurry, which can be used as a fertilizer to improve soil fertility and crop yields.The utilization of natural resources for cooking gas generation has been a long-standing practice in various countries. However, the prevalent issue with existing systems lies in their chambers, which are prone to damage due to low-quality materials. Additionally, their construction often requires skilled labor and high-quality materials, posing challenges in affordability and accessibility. A comparison study conducted by referring problems that lead to troubleshooting in Biogas Plants between various types of biogas and a novel balloon-type biogas system has been designed and developed to address these limitations. The system exhibits cost-effectiveness, weather resistance, and thermophilic characteristics, enabling operation at high temperatures of 50°-55°C, within the range suitable for the digestion of mesophilic bacteria (40°-50°C) that contribute to gas generation. The work also elaborated to enhance biogas efficiency by incorporating a scrubber module capable of removing impurities such as hydrogen sulfide (H2S), carbon dioxide (CO2), and water vapor (H2O).
Potentials for alternative energy in Nigerian cities and remote communities
Authors: Obi Nicholas I. , Okeke Francis O. , Mba Emeka J. , Udeh Clifford A. , Okosun Andrew E. , Oforji Peter I.
Published: October 2023

The energy sector of Nigeria’s economy constitutes a critical challenge. This sector has defied all efforts for its reform and restoration largely due to ineffective and poor policy implementation. In the 20th century, oil was the main driving force in global geopolitics and the main force behind massive industrialization. However, oil is moving in a downward trend. In its place will be an array of technologies, in the form of alternative energies with long term prospects. The standard of living of a given country can be directly related to per capita energy consumption but energy crisis is on the increase due to population and improved standard of living especially in developing cities. The aim of the study is to identify alternative energy potentials for Nigeria in view of her current energy challenges. The methodology applied in this study include case studies and review of existing literature on the subject. Identified energy crises include, incessant power outage, shortage and scarcity of petroleum products, high electricity bill, vandalization of pipelines and oil installations. The paper discussed the energy crises in Nigeria, the potentials of alternative energy technologies, and the challenges of its development for Nigerian cities and recommends that renewable energy and energy efficiency are necessary factors to achieve sustainable development in Nigeria.
Increasing the calorific value of Angren lignite coal by an upgraded device
Authors: Babakhodjaev Rakhimjon , Kurbanbaeva Miyasar , Kavkatbekov Murodjon
Published: October 2023

the article presents the classification of the improved drying and enrichment device for increasing the calorific value of Angren B2 coal, the behavior of heat carriers, physical model, operation process, hydrodynamics of the abstract fluidized bed. Experiments were carried out on this device, preliminary results were obtained, and examples of analyzes that determine the reliability of the research are presented. The empirical equation of the results of the research is defined in term 6 in the polynomial linear equation and shown using a graph. In addition, the reliability of the research results was analyzed by regression and the reliability was 96%.
Optimal Sizing and Sitting of Distributed Generation in Distribution Network considering Power Generation Uncertainty
Authors: Khasanov Mansur , Kamel Salah , Jurado Francisco , Kurbanov Abror , Jalilov Urinboy
Published: October 2023

This paper presents an application of the recent metaheuristic Geometric Mean Optimizer (GMO) for the allocation of renewable energy sources (RES), including wind turbine (WT) and biomass-based Distributed Generation (DG) units in the distribution network (DN). The primary objective function is to minimize the total power and energy losses. The Weibull probability distribution function (PDF) is employed to describe the uncertainty of wind speed. The high penetration of RES with intermittent availability and demand variations has introduced many challenges to DN, such as power fluctuations, voltage rise, high losses, and low voltage stability. Therefore, the use of dispatchable biomass is considered to smooth out supply fluctuations and maintain supply continuity. A standard IEEE 69-bus test system is used to verify the performance of the proposed approach. The simulation results and comparison with other techniques demonstrate the significant energy loss reduction achieved by the proposed technique.
Study on the cost effectiveness of a combined evaporation unit
Authors: Mukhtarov Farrukh , Akhmedov Akhmad , Usmonov Nizomjon , Usmonov Jamshid
Published: October 2023

In a thermal power plant, water treatment plants are used to perform body losses in the main steam cycle using one of the following methods of water preparation: chemical, thermal, membrane or combination of them. One of the main advantages of thermal desalination is the low impact on environmental pollution. In the light of the ever-increasing environmental demands on energy processing systems, thermal desalination is becoming an increasingly preferred method of water treatment, since it allows wastewater to be used as feed water for evaporators. In our country, multi-stage evaporation units are quite widespread. They are used as operating units in industrial heating plants and as backup for condensation plants. These units have high thermal costs and are characterized by an excess of secondary vapour of the last evaporation step, which needs to be continuously removed from the plant to avoid loss of productivity. The main objective of this work is to minimize the total and thermal costs of the production of additive water in the main steam turbine cycle of the thermal power plant and the treatment of wastewater in evaporation complexes, as well as to determine the technical economic effectiveness of applying some technical solutions for the recovery of excess steam in multi-stage evaporation units.
Study on the effect of electric pulse treatment for disinfestation of vegetables
Authors: Bozorov Elmurod , Abdullayev Husniddin
Published: October 2023

This paper describes a method of using pulsed discharge to control nematode diseases on tomato and cucumber rhizomes and crops grown in dacha plots. When pulsed discharges are applied to living tissue, certain chemical, physical, and biological processes occur, depending on the pulse energy, pulse discharge current, pulse discharge voltage, pulse discharge exposure time, pulse discharge impact current, and other similar factors. Electric pulses were applied to grafts of nematode-infested vegetables, tomatoes and cucumbers, to measure grafting ability. Crop yields were estimated by the total amount of produce grown on arable land, and the level of yield enhancement was determined by land sedimentation and proper placement of varieties and plant species. Proper selection of modern high-yielding varieties imported from Uzbekistan provides resistance to external adverse effects of nature and diseases. The creation of high-yielding varieties requires the discovery and cultivation of resistant hybrid varieties and the development and introduction of new progressive technological methods of plant cultivation. The objective of this study was to identify the main factors affecting the electric pulse discharge treatment of tomato and cucumber root crops infected with nematodes and their larvae. Various diseases occur in cotton, cereals, melons, vegetable crops, and indoors(greenhouses) on newly established farms in the Republic. Yields are particularly high in vegetable, melon, and greenhouse fields. In recent years, the impact of nematodes on plants has caused severe damage to crop yields. Treating crops with this formulation prevents nematode infestation of leaf veins. The economic damage caused by nematodes to agriculture is enormous. For example, in greenhouse vegetables (cucumbers and tomatoes) this indicator reaches 60% and in potatoes 80%. Therefore, the proposed method is realized in combination with an agrotechnical treatment process that is energy-saving, environmentally safe, and productive.
Development of a simulation model for assessing the technical condition of transformers exploited in hydroelectric stations
Authors: Yusupov Dilmurod , Artikbayev Nodir , Kutbidinov Odiljon , Toshpulatov Nusratillo , Babayev Aziz , Matchonov Oybek , Vokhidov Akmal
Published: October 2023

Supplying consumers with continuous electricity is one of the urgent problems of today. The main part of electricity is produced by hydroelectric stations. The perfect operation of the main electrical equipment of hydroelectric power stations is related to the reliable operation of the electrical equipment in operation. The flawless operation of power transformers in operation at hydroelectric power stations is evaluated by their technical condition. The technical condition of power transformers is determined by their electrical and non-electrical indicator values. In this article, a simulation model for determining the value of the technical condition of power transformers in operation at hydroelectric power stations using fuzzy logic has been developed.
Calculation of the thermal balance of the photocell during operation and removal of heat
Authors: Murodov Muzaffar , Nabiev Murodjon , Amir Hababa Mohamad
Published: October 2023

The heat exchange of the photoelectric module with the environment and its changes in constant temperature were analyzed. Its temperature depends on the ambient temperature and the flux density of solar radiation, the heat balance equation is formed. The maximum concentration coefficient corresponding to the accepted limit temperature of 85 °C of the photocell was determined. It turned out that in the case of arbitrary installation of photoelectric modules, the maximum concentration coefficient does not exceed K = 3 at ambient temperature 25 °C, and K = 2,5 when installing the roof. An increase in the unit concentration coefficient in the summer leads to a constant temperature rise of the photocells to 18-22 °C, depending on the method of installation. A sandwich structural method of photoelectric module surface cooling was developed taking into account the increase in ambient temperature.
Influence study of thermostabilizers on the properties of cellulose triacetates
Authors: Baltabaev Rahmatilla , Eshmukhamedov Murod , Abidov Aziz , Rashidov Shokhzodbek
Published: October 2023

In the chemical and petrochemical industry, the primary focus for workers in the upcoming years is to develop innovative and secure technologies and equipment that comply with stringent quality standards. This imperative encompasses the production of materials, devices, and other products that meet the highest global benchmarks in technical and economic aspects. Emphasizing the implementation of progressive technologies and advanced production methods is crucial for achieving substantial improvements in labor productivity across all sectors of the national economy, with special attention paid to the chemical industry. This paper work presents the results of a study on increasing the thermal stability of cellulose triacetate by introducing stabilizers into its composition. Regularities of plasticization of cellulose triacetate with low- and high-molecular compounds have been established. As a result, the deterioration of the physical and mechanical properties of polymer materials processed at high temperatures occurs due to thermo-oxidative degradation, which leads to changes in the composition of the main polymer chain and a decrease in molecular weight. The application of stabilizers is proposed to prevent this process at high temperatures.
Study on energy consumption regulation of devices in industry enterprises
Authors: Khoshimov Ural , Khushiev Sirojiddin , Karakulov Shamsiddin
Published: October 2023

As a result of the implementation of certain standards for the energy consumption of electricity consumers used in industrial enterprises, the work on prevention of excess energy waste in the enterprise is gaining urgent importance. Grouping devices with the same performance into groups, monitoring energy consumption and early detection of deviations from established limit parameters, has a positive effect on energy and resource saving in the enterprise.
Concrete with a complex additive based on a superplasticizer and an organosilicon polymer
Authors: Asatov Nurmukhammat , Raxmonov Navruz , Ablayeva Ugloy
Published: October 2023

Depending on the functional purpose, different requirements are imposed on the products. In particular, reinforced concrete products used in irrigation and drainage construction, along with increased strength and frost resistance, are required to have increased water resistance. For the water resistance of concrete, through macropores (filter capillaries) are dangerous, which are formed as a result of uneven thermal expansion of concrete components during heat treatment, as a result of plastic shrinkage and sedimentation during compaction. The relationship between the structure and impermeability of concrete is very complex.
Implementation of eggshell extracted calcium acetate in biocementation via soybean urease
Authors: Hoque Md Azizul , Islam Md Hamidul
Published: October 2023

Biocementaion, a promising soil improvement technique, mostly utilizes calcium chloride (CaCl2) as its calcium source. However, using CaCl2poses a critical environmental problem of producing ammonium chloride as a by-product. Alternatively, when calcium acetate (Ca(CH3COO)2) is used as the calcium source, the production of ammonium chloride during biocementation can be reduced. Ca(CH3COO)2can be easily derived from waste eggshells. Nevertheless, such research has been conducted only with Microbial Induced Carbonate Precipitation (MICP) to date. This paper aims to study the implementation of eggshell Ca(CH3COO)2in the more effective biocementation approach: Enzyme Induced Carbonate Precipitation (EICP) via soybean urease. For this study, EICP solutions of varying molar ratios and concentrations were studied for their precipitation efficiency and reinforcement effect on poorly graded sandy soil. The findings showed that the EICP solution composition of 1:1 molar ratio between Ca(CH3COO)2and urea, added with 50 g/L soybean solution reached the maximum precipitation efficiency. It also produced the highest 7-day UCS of 371 kPa at a calcium carbonate content of 0.40%. Furthermore, the eggshell-soybean EICP produced 8.5% higher UCS than CaCl2-soybean EICP despite having similar calcium carbonate content.
Acid-resistant liquid glass coatings using soda ash production wastes
Authors: Alieva Rena , Mukhamedbaeva Zamira , Olimova Nargiz , Zakhiyevna Gaukhar
Published: October 2023

This article presents the results of research on the topical problems of protection of building structures, structures and products of various purposes operated in aggressive, mainly acidic environments. The existing scientific bases of obtaining high-performance acid-proof cements on the basis of liquid glass with the use of local raw materials and secondary resources of various industries are developed. Questions of increasing and improving the properties of acid-resistant liquid glass compositions by changing the input components: a primer, a filler and a hardener by introducing various active and inert additives, modifying the liquid glass, optimizing curing regimes, selection of compositions for specific operating conditions are considered.
Tourist Response as Water-based Seaplane Purposes for Island Tourism: A Literature Review
Authors: El Hafizah Nafilah , Ahyudanari Ervina , Lukitosari Valeriana
Published: October 2023

In a journal review, the conclusion of the statistical and mathematic model was presented to illustrate the impact of various factors on tourist preferences, facilities and infrastructure available as tourism support facilities. On of the most important sectors that drives the national economic is tourism sectors. This literature review covers a lot of research conducted on sustainable tourism, especially regarding transport facilities and other aspects. Other aspects of tourism, namely facilities, accomodation, sosial-culture, environment, and economy, are also considered. The main determinants of tourism are assessed using a scientific approach to evaluate the attractiveness of tourist sites by considering many aspects. Several results have indicated that natural resources, island culture, and access infrastructure are important determinants of tourism demand in various countries. This discussion may be useful for the authorities involved in tourism development and sustainability in the future. The study primarily focused on accessibility, tourism attraction, environment, etc. With these results, important tourist sites can be prioritized for enhanced accessibility and promoted as major tourist destination in the country. Research mapping to establish the basic model can be based on simulation approach and statistical analysis, such as a system dynamic model and other relevant analysis.
Study on the analysis of travel behavior: A review
Authors: Firdausi Mutiara , Ahyudanari Ervina , Herijanto Wahju
Published: October 2023

Travel behavior analysis involves the utilization and examination of travel demand through the application of theories and analytical techniques derived from diverse scientific disciplines. There are many methods used by researchers in analyzing travel behavior. Mode selection is the stage where the transportation planning process is responsible for determining the travel load or knowing the number of people and goods, then selecting the available transportation models that serve as the starting point of the destination. Travel factors have a strong influence on a person’s travel behavior, (trip maker behavior), including income, vehicle ownership, vehicle condition, settlement density of one’s socioeconomic conditions. This paper describes the disadvantages and advantages of travel behavior modeling analysis and factors that influence the choice of modes based on travel behavior, so that in the future researchers can use it as an illustration in determining the right analysis.
Creation of technology for desalination of saturated diethylene glycol substance in East Berdak gas complex preparation plant
Authors: Murodov Abdulaziz , Xabibullaev Saidaziz , Maxmudov Nazirila , Daminov Temurbek , Qarshiyev Abduhoshim
Published: October 2023

This article delves into a range of intricate challenges stemming from the salting issues associated with saturated diethylene glycol substance within the East Berdak complex gas preparation unit of the Ustyurt gas production department at JSC “Uzbekneftgaz.” The scholarly discourse encompasses an in-depth exploration of the rigorous scientific inquiry undertaken by a dedicated research team, inclusive of comprehensive laboratory analyses, with a focal emphasis on devising effective solutions to mitigate the challenges posed by diethylene glycol salting. A significant portion of the article is dedicated to elucidating the existing desalination techniques employed to counteract the salting phenomena. A thorough exposition is offered on the novel approach developed as a countermeasure, with a juxtaposition to the conventional methods currently in use. Noteworthy attention is accorded to elucidating the intrinsic distinctions between the newly crafted methodology and the pre-existing solutions, underscoring the innovation inherent in the proposed approach. In essence, this article delves into the complexities and intricacies surrounding diethylene glycol salting issues within the East Berdak complex gas preparation unit. By synthesizing meticulous scientific research, laboratory analyses, and an innovative problem-solving approach, it offers a comprehensive understanding of the challenges posed by diethylene glycol salting and endeavors to pave the way for an efficient, contextually relevant, and effective solution.
Implementation of an integrated management system in calcium soda production
Authors: Ametova B. , Boboyev G. , Djumaniyazova N.
Published: October 2023

By amalgamating these essential pillars, the integrated management system endeavors to revolutionize the calcium soda production paradigm, ensuring harmonious coexistence between economic progress and ecological responsibility. This manuscript will explore the key components, challenges, and potential benefits of integrating such a system while shedding light on the transformative impact it can have on the industry as a whole. As we embark on this journey towards a more sustainable and efficient future, the implementation of an integrated management system emerges as a cornerstone in shaping the trajectory of calcium soda production and contributing to a greener and safer world. This article highlights the significance of integrating standards in the soda ash production process, focusing on improving product quality, ensuring competitiveness, and meeting high demand in domestic and foreign markets. It also explores the development and implementation of a quality management system (QMS) based on the ISO 9001:2015 standard. Additionally, the advantages and disadvantages of obtaining SMT certification for compliance with international ISO standards are discussed.
Numerical Analysis of Compound Walls of Brick Masonry, Strengthened with C-FRP Laminate under Explosive Detonations - Afghanistan Scenario
Authors: Anas S. M. , Al-Dala’ien Rayeh Nasr , Alam Mehtab , Kanaan Manal Hadi Ghaffoori , Akram Shahbaz , Haris Mohd
Published: October 2023

Afghanistan, a nation plagued by wars, terrorism, and counter-terrorism, has borne the brunt of these conflicts. The common people of Afghanistan are weary of the continuous cycle of attacks and counter-attacks by warlords. Even places of worship and those who gather there are not spared from these acts of violence. For years, explosive blasts have targeted the compound walls surrounding these religious structures. In this research, we investigate the impact of such blasts on free-standing URM walls commonly used in Afghanistan. Using ABAQUS/Explicit code, we conduct nonlinear analysis to examine the blast performance of these walls. Additionally, we retrofit the walls with a high-strength C-FRP laminate. To optimize computational time, we employ a macro strategy. The results show that the strengthened walls exhibit comparable blast performance. Importantly, when the laminate is applied to both faces, there is no longer a need for increased wall thickness in the masonry construction.
Numerical Modeling of Steel Column for its Response to Large Explosive Loading using CEL-FEM Approach
Authors: Anas S.M. , Alam Mehtab , Kanaan Manal Hadi Ghaffoori , Matchonov Oybek , Muzaffarov Shavkat
Published: October 2023

In the past few decades, there has been a growing public concern regarding the protection of infrastructures against extreme events, specifically explosive detonations. Traditional structural design has predominantly focused on accounting for gravity, seismic, and wind loads as the primary factors to consider. The rise in subversive attacks has led to a heightened focus on blast load and its impact on infrastructures. Unconfined, surface explosions are a common type of terrorist attack that occurs outside of buildings. This has necessitated a greater understanding of the effects these explosions can have on structures. A comprehensive numerical model was created in Abaqus for a steel column measuring 2.41m in length and having a W150x24 cross-section. The model was then subjected to a powerful explosion equivalent to 100kg-TNT, with a standoff distance of 10.30m. To achieve this, an Eulerian-Lagrangian approach coupled with the Finite-element method (CEL-FEM) was employed. A thorough investigation was conducted by modifying the explosion's altitude (i.e., blast height), and the subsequent dynamic responses were analyzed and discussed. The outcomes of this investigation significantly enhance our comprehension of how steel columns respond when subjected to intense explosive forces.
Hydrogeochemical analysis of groundwater in residential areas around the Terjun landfill in Medan city, Indonesia
Authors: Nurfahasdi Meutia , Muzambiq Said , Herlina Netti , Rahayu Silda Adi , Noventino Manihuruk Jonathan , Kurambaev Sherzod , Musayev Sharof
Published: October 2023

Open dumping is the type of landfill used in Terjun landfill. This type of landfill has a high potential for pollution to the environment, especially in groundwater quality. This study aims to determine the quality of groundwater in the Terjun landfill area and its hydrogeochemistry. The methods proposed in this research are Trilinear Piper Diagram Analysis (1944), Stiff Quadrangle Diagram Analysis (1951) and Durov Diagram Analysis (1948). The elements analyzed include Calcium (Ca2+), Sodium (Na+), Magnesium (Mg2+), Potassium (K+), Chloride (Cl-), Bicarbonate (HCO3-) and Sulfate (SO42-). The results obtained on the electrical conductivity value ranged from 100-1100 micromhos/cm, indicating the classification of the water as fresh water. Analysis of the major ion test results of each sample using the three methods shows that the dominant ion content in the borehole groundwater is Cl- ions in borehole 1 and HCO3- ions in the other boreholes. On the Piper diagram, it can be determined that the facies or type of borehole groundwater that has been tested is Ca2+-HCO3-. Then the Durov diagram can be divided into 2 groups, namely the simple dissolution or mixing and reverse ion exchange groups. When looking at the results of the major ion test, sample point 1 has a high level of Cl- ions influenced by leachate water and a fairly close distance to the landfill.
The licorice (Glycyrrhiza glabra L.) metabolite derivatives as bioinsecticides against Аnacanthotermes turkеstanicus termites
Authors: Tilyabaev Zaitjon , Khashimova Мukhabbat , Mathur Vartika , Esanov Rahmat , Gafurov Мakhmudjan , Rustamov Kahramon
Published: October 2023

This article presents the results on the termiticidity of the compounds produced by the reactions of glycyrrhizic acid (GA) with 2-aminothiazole, 3-amino-1,2,4-triazole and 2-aminobenzothiazole. The biological effect of the studied compounds has been found to be dose-dependent. Among the GA derivatives the maximum insecticidal activity has been exhibited by the GA derivative with 2-aminobenzothiazole. Based on the results of the experiments, it has been concluded that the structural-functional approach to the search for biotermiticides is one of the alternative ways to develop environmentally safe means of termite control.
Influence of carboxy methyl cellulose (CMC) colloid on irrigation frequency of planting material with a closed root system
Authors: Mamutov Bakhram , Butkov Evgeniy , Yuldashev Hamza , Tasheva Umida , Otaeva Farida , Toshpulatov Nusratillo
Published: October 2023

This article discusses the impact of different amounts of carboxymethyl cellulose (CMC) colloid on the frequency of watering seedlings with a closed root system in containers. The study found that increasing the CMC dose from 0.05% to 2.0% of the dry soil mass resulted in a decrease in the number of irrigations per month during summer from 5-6 to 2-3, an increase in the frequency from 5-6 to 11-16 days, and a reduction in the volume of irrigation water per container from 3700 cm3 to 2250 cm3 during the growing season. However, it should be noted that doses higher than 0.4% resulted in the formation of a thick soil crust in the containers, which negatively affected seed germination and plant growth.
Investigation of two-dimensional unsteady motion of deformable raw roller during saw ginning
Authors: Sirojiddinov Fazliddin , Mardonov Botir , Abbazov Ilkhom , Sharopov Bobir
Published: October 2023

In this article, based on the analysis of research conducted by scientists in many fields on increasing the productivity of sawing gin, the requirements for sawing gin to improve the workability of gin, increase fiber quality, and reduce energy consumption, as well as its separation into technological parts, and a single conclusion, collecting the conducted research it was mentioned that it should be released. It is explained the requirements for cotton ginning equipment in cotton ginning cluster enterprises and the need to carry out the innovative approach of sawing gins, dividing each technological process into separate technological parts to fulfill these requirements. The technological process of the sawmill consists of a complex of 9 technological parts.
The Routine Performance of Open-Heart Surgery Without Blood
Authors: Housman Leland B. , Litchford Britt , Mazur John H.
Published: October 2023

The dramatic geometric increases in open-heart procedures have aggravated demands on blood banks. Recent surveys indicate a continual national average of eight units/patient. This study was undertaken to demonstrate the feasibility and advantages of bloodless cardiac surgery. Two groups of 100 patients each, similar in age, sex, procedures performed and pre-operative hematocrit values are analyzed. Group I patients were transfused routinely; every effort was made to avoid blood in Group II. Intra-operative PaO2, pH and Hematocrit values were similar. Total measurable blood loss was less in Group II, reflecting more careful technique. Mean transfusion (units/patient) was 8.5 in Group I, and only 0.5 in Group II (75% received no blood, 95% 2 units or less). Oxygen requirements, acidosis, pulmonary complications and hepatitis (zero) were Jess in Group II. All Group II patients received oral FeS04 and two weeks post-discharge 92% had hematocrit values ≥ 30 vol% with 56% being ≥ 35 vol %. Cardiac surgery can be safely performed without transfusion, specific benefits are afforded, and consequently this technique is recommended.

The volume of cardiac surgery performed in the United States has increased in the last five years, chiefly due to the advent of coronary artery bypass surgery. 1 This has placed an obligatory and sometimes unmeetable obligation on blood banks across the country, since the average amount of blood used per cardiopulmonary bypass procedure remains 8.5 units/patient nationally. 2 Based on laboratory and clinical reports, 3.4 there is ample evidence that cardiac surgery can be performed safely without the use of autologous banked blood. The elimination of transfusion, in addition to relieving the everincreasing demands on blood banks, also dramatically decreases the incidence of hepatitis, transfusion reaction and various coagulopathies. The techniques of hemodilution may well enhance tissue perfusion during bypass, 3,5,6 and combined with autologous transfusion with the patient's own blood further decreases the necessity for blood transfusion. This study was undertaken to demonstrate not only the feasibility but the advantages of bloodless cardiac surgery.
Die frühe Nutzenbewertung nach § 35 a SGB V – Ein Überblick über das Verfahren
Authors: Behring Antje
Published: October 2023

Für die Bewertung des Zusatznutzens nach § 35a SGB V gelten besondere Anforderungen, die nur zum Teil mit den Anforderungen der Zulassung vergleichbar sind. Das Verständnis der zu Grunde gelegten Maßstäbe und deren Zielsetzung hilft, die differenzierten Entscheidungen zum Zusatznutzen nachzuvollziehen und von der Arzneimittelzulassung abzugrenzen. Das Verfahren der frühen Nutzenbewertung und die festgelegten Entscheidungsgrundlagen sind nachfolgend erläutert.
Bewegungsförderung fördert
Gesundheitsförderung
Authors: Schmidt Sandra , Dresel Uwe , Baldus Angelika
Published: October 2023

Liebe Leserinnen und Leser,

in den kommenden Jahren bis 2035 gehen 11 Millionen Babyboomer in Rente, das sind
25% aller Arbeitnehmer in Deutschland. Nur zwei Drittel der freiwerdenden
Arbeitsplätze können durch die jüngeren Generationen
ausgefüllt werden. Dadurch wird sich der jetzt schon bestehende
Arbeitskräftemangel in der Pflege noch drastisch erhöhen, und dies
bei steigendem Bedarf. Denn über kurz oder lang benötigen die
Babyboomer auch rehabilitative und pflegerische Leistungen.
Bewegung, körperliche Aktivität und
Alter
Authors: Köppel Maximilian
Published: October 2023

Durch den demografischen Wandel und die steigende Lebenserwartung werden
altersassoziierte Erkrankungen in den kommenden Jahrzehnten immer
präsenter. Körperliche Aktivität und
körperliches Training stellen in diesem Kontext wirksame
Maßnahmen dar, um die Erkrankungsraten einzudämmen und
Betroffene im Umgang mit ihrer Erkrankung zu unterstützen. Gerade bei
älteren Menschen, die ein erhöhtes Sturzrisiko besitzen, kann
körperliches Training dem Risiko entgegenwirken und darüber
hinaus sturzassoziierte Verletzungen und Frakturen reduzieren. Es konnte gezeigt
werden, dass Training und körperliche Aktivität auch eng mit der
Mortalität assoziiert sind und insbesondere Menschen mit Vorerkrankungen
davon profitieren. Um die Effekte der Bewegung zusätzlich zu
verstärken, hat sich in vielen Studien die Supervision als wichtiger
Moderator herausgestellt. Eine professionelle Betreuung kann also dabei helfen,
die positiven Auswirkungen von körperlicher Aktivität und
Training weiter zu maximieren.
Effects of Training on Running Cost and Aerobic Capacity in
Individuals with Obesity
Authors: Castro Eliane Aparecida , Silva Elisangela , Benito Pedro J , Neiva Cassiano Merussi , Pessôa Filho Dalton Müller
Published: October 2023

This study investigated running cost (CRun), peak oxygen consumption
(V̇ O2peak), and ventilatory threshold (VT1)
responses to exercise programs for individuals with obesity. Ninety-four
individuals (38.2±7.7 years;
33.4±2.9 kg/m²) were assigned into strength
(n=24), endurance (n=26), combined (n=22), and physical
activity (control, n=22) groups for 22 weeks, plus diet recommendation.
The V̇ O2peak, VT1, and CRun were
assessed through a maximal incremental step test. The change of V̇
O2peak in combined (9.9%) differed from the other groups,
with lower values in women than men (0.7% vs. 6.2%). The
VT1 change in combined (16.4%) differed from the strength
(4.9%) and physical activity (1.2%) groups, with the change in
endurance (12.7%) also being higher than the physical activity group.
Only men in the combined group increased absolute V̇ O2peak,
while both sexes increased VT1 in the endurance and combined groups.
No effects for groups and sex were significant for CRun in moderate
(VT1)
running zones, despite CRun changes in <VT1 and
>VT1 zones correlated with the alterations of V̇
O2peak and VT1 (r²=0.29–0.59).
Therefore, moderate aerobic exercise stimulus is suitable for VT1
improvement in individuals with obesity, with the increase in CRun
associated to the chances of increasing V̇ O2peak in men and
when combining strength with aerobic exercises.
Practical Aspects of Cardiopulmonary Exercise Testing in
Children
Authors: Takken Tim , Hulzebos Erik H.
Published: October 2023

The use of cardiopulmonary exercise testing (CPET) in pediatrics provides
critical insights into potential physiological causes of unexplained
exercise-related complaints or symptoms, as well as specific pathophysiological
patterns based on physiological responses or abnormalities. Furthermore, CPET
helps evaluate exercise performance in children with chronic
(lung/heart) diseases. For instance, it can ascertain any adverse
reaction to exercise and estimate the effects of specific treatment measures. It
affords a global assessment of the pathophysiological patterns, responses and
abnormalities to exercise that is inadequately reflected by resting lung
function and/or cardiac function assessment. Clinical interpretation of
the results of a CPET in pediatrics requires specific knowledge regarding
pathophysiological responses and interpretative strategies that can be adapted
to address concerns specific to the child’s medical condition or
disability.
Boryl Acrylaldehyde: An Elusive Member of the α-Boryl Aldehyde Class of Reagent
Authors: Yudin Andrei K. , Trofimova Alina , Brien Chelsey , Trinchera Piera , Tien Chieh-Hung
Published: October 2023

We describe a synthetic route to boryl acrylaldehyde, an amphoteric molecule that features BMIDA and aldehyde functionalities attached to an sp2-carbon center. As the project unfolded, conventional protocols based on aldol condensation turned out to be unsuccessful. We eventually zeroed in on oxidative conditions that preserved the BMIDA group and delivered the desired aldehyde functionality. During our investigation, it became clear that boryl alcohol displays hemilabile N–B bonding, which differs dramatically from the previously described congeners with the sp3-carbon center connected to boron. We have attempted to understand the origins of this behavior using DFT calculations. Overall, boryl acrylaldehyde can be considered as an attractive entry point in synthetic methods. These studies are underway in our laboratory.
Adoption of fourth industrial revolution 4.0 among Malaysian small and medium enterprises (SMEs)
Authors: Shahzad Arfan , bin Zakaria Mohd Syarol Azuan , Kotzab Herbert , Makki Muhammad Abdul Majid , Hussain Aamir , Fischer Julia
Published: October 2023

Using Industrial Revolution 4.0 (IR4.0) technology, companies can upscale their innovation in organizing, managing, and controlling the value chain life cycle. IR4.0 is anticipated to bring challenges and opportunities to developing economies such as Malaysia, but due to its novelty to the Malaysian business community, the concept still needs clarity in its definition for proper understanding and business practice. This paper aims to examine the impact of IR4.0 adoption on Malaysian small and medium enterprises (SMEs) by analyzing the organizational readiness, relative advantage, compatibility, top management support, government regulation, and competitive pressure, and its relationship with the adoption of IR4.0 to Malaysian SMEs. This study framework is based on the diffusion of innovation theory (DOI) and technology–organization–environment (TOE) framework. The study results verified the importance of relative advantage, compatibility, competitive pressure, and top management support as significant predictors of IR4.0 adoption. The study is expected to benefit regulators and business ecosystems in understanding the challenges in implementing IR4.0 in Malaysia and formulating intervention processes and programs for successful IR4.0 adoption.
Life satisfaction and acculturation of European students in the Chinese context
Authors: Peng Renzhong , Zhu Chongguang , Liu Na
Published: October 2023

Life satisfaction is a crucial aspect of psychological well-being for international students during the process of acculturation. Among international students in China, European students constitute a significant demographic, making it imperative to examine their life satisfaction. However, existing research has primarily focused on theoretical literature reviews regarding the factors that impact European students’ life satisfaction and acculturation, with few empirical investigations conducted. This study aims to explore European students’ perceptions of life satisfaction in acculturation to China and the factors affecting their life satisfaction in acculturation. Through three rounds of semi-structured interviews involving 27 European students, this study employed NVivo 12 software to conduct sentiment analysis on interview materials to investigate European students’ perceptions of life satisfaction. Additionally, a coding analysis was conducted to identify the factors affecting their life satisfaction in acculturation. The results from the sentiment analysis reveal that European students generally experience a relatively high level of life satisfaction while acculturating to China. The coding analysis highlights several factors that affect their life satisfaction during this process, including social activity, social support, academic performance, language proficiency, consumption, diet, transportation, and safety. These findings offer researchers and scholars a theoretical understanding of acculturation and life satisfaction research on European students in China and could be referential for international education administrators.