bluuebunny/crossref_metadata_2025 huggingface dataset:
Tingkat Pengetahuan tentang Sindrom Premenstruasi dan Penanganan Sindrom Premenstruasi
Authors: Puspitasari N.F. Sherly , Suryani Dyah
Published: November 2022

Background: Adolescence is a period of a child turned into an adult. Adolescence women two yearsearlier than men. Data pornography, the adolescent is a large population than the population of theword. WHO and some other word body called on all countries of Southeast Asia to provide itscommitment to observe and protect the needs of adolescents and information, skills, service, and safeenvironment and supportive of essential reproductive health. The reproductive period in the life of awoman who started from menarche until menopause occurs. The menstrual period they aresometimes accompanied by disturbances such as premenstrual syndrome (PMS). It is estimated that80-10% of women do not have PMS, and approximately 25-40% have PMS. Most women experiencePMS symptoms in a long period. The symptoms are of an emotional outburst in the form of anger,high sensitivity, sad, lonely, until the desire to commit suicide. Is research target is to know therelation of between level of knowledge of syndrome premenstrual with the handling of syndromepremenstrual of at adolescent of age 12-15 year in SMP PGRI Bantul.Methods: The study was observational analytic with the cross-sectional approach. The samples wereall students SMP PGRI Bantul amounting to 138 students and measuring the level of knowledge andhandling of premenstrual syndrome using questioner. Analysis of data used univariate and bivariateanalysis with chi-square. Result: There was a relationship between the level of knowledge about premenstrual syndrome withthe handling of premenstrual syndrome in adolescents age 12-15 years in the SMP PGRI Bantul withthe value of P=0,000. Conclusion: There was a relationship between the level of knowledge about premenstrual syndromewith the handling of premenstrual syndrome treatment. Key words: level of knowledge, premenstrual syndrome, adolescent
Pengetahuan Ibu tentang Posyandu dengan Cakupan Kunjungan (D/S) Balita
Authors: Supriyanti Anisa , Nurwiandani Widy , Yuliantina Diah
Published: November 2022

Background : Based on the Republic of Indonesia Ministry of Health in 2013 the coverage (D / S) of toddlers in Indonesia amounted to 80.30%, in the Special Region of Yogyakarta in 2014 reached 79.1% had not met the Ministry of Health Renstra target, the level of community participation in Bantul Regency in weighing Posyandu (D / S) of 79.02% and still below 80%, the number of under-five deaths in Bantul Regency in 2014 was 131 toddlers, the highest number of under-five mortality among the five regencies in DIY, for D/S coverage which was still low in Bantul Regency below 80% namely Bantul 1 Health Center is 75.47%, in the Bantul I Health Center area the scope of weighing (D/S) is still low, namely in Trirenggo Village the D / S coverage in October 2015 was 75.95%. Objective: To find out the relationship between the knowledge of mothers about posyandu and the coverage of visits (D / S) of toddlers at Posyandu Mekarsari, Trirenggo, Bantul, Yogyakarta.Method: This study was conducted at Mekarsari Trirenggo Bantul Posyandu in February, the study design used Bivariate Correlation with a cross sectional approach. The population of mothers who have children aged 12-60 months who live in the Mekarsari Posyandu area is 65 respondents. The sampling technique by means of total sampling. Analysis using Chi Square.Results: By using the Chi Square formula, the value of X2 calculated is equal to6,644 with an error rate of 5% (X2 count> X2 table) and p-value <0.05. Respondents in this study can be categorized as having less knowledge, namely 32 respondents (49.2%) and not active in conducting Posyandu visits 34 respondents (52.3%).Conclusion: There is a relationship between knowledge of mothers about Posyandu and coverage of visits (D / S) of children under five at Posyandu Mekarsari Trirenggo Bantul.Keywords: Knowledge about Posyandu, coverage of visits (D/S) toddlers
Tingkat Pendidikan Ibu Dan Pola Asuh Demokratif Pada Anak Usia 4 Sampai 6 Tahun Di Tk Kuncup Harapan
Authors: Revika Era , Erviana Irma , Tunjung Galuh
Published: November 2022

AbstractParenting patterns will shape behavior in children. Democratic parenting will make children more independent, easy to make decisions, and more confident so that they will get success in the future. Parental education is one of the important things in life because education provides broader insight and influences good parenting for their children.This study aims to determine the correlation between mother's level of education and democratic parenting in children aged 4 to 6 years.This study used a cross-sectional method at the Kuncup Harapan Kindergarten. The subject of this research is the parents of students. The population of this study was all parents of students. 53 respondents in this study were selected using simple random sampling. The instrument in this study was a questionnaire.Results: The results of the analysis (Sig 0.017<0.05) showed a correlation between the level of mother's education and democratic parenting in students aged 4 to 6 years in Kuncup Harapan Kindergarten..Keywords: education level, democratic parenting
Knowledge, Attitude and Practice of Type II Diabetes Mellitus Patients Attending a Tertiary Care Teaching Hospital of Western Maharashtra; a Cross Sectional Study
Authors: Verma Dr. Priyank Rajendra , Attar Dr. Nazir , Tungikar Dr. Sudhir L. , Patil Dr. Ranjeet
Published: November 2022

Diabetes mellitus is one of the most common non-communicable diseases and is the fifth leading cause of death in most developing countries. There is always a need to investigate knowledge, attitude and behavior among diabetic patients to aid in future development of national health programs and techniques for effective prevention. Objective: To assess knowledge, attitude and practice of type II diabetes patients attending tertiary care teaching hospital of western Maharashtra. Material and Methods: This was observational cross sectional study. Patients above 18 years of age, either gender attending outpatient department of general medicine including newly diagnosed and follow up type II diabetes were included by using simple random sampling. Patients not willing to participate, patients who were not physically or psychologically able excluded. Total 275 patients included as per inclusion and exclusion criteria. Results: Out of total patients 57.82% (159) and 41.18% (116) were males and females respectively. In this study majority of patients were of 51 to 60 years (35.64%) age group followed by 61 to 70 years (28.73%) and 41 to 50 years (24.36%) age group. On analysis we found that though the majority (92.75%) of the patients aware about what diabetes is. Responses on attitude domains were somewhat mixed and 65.81% and 44.72% do not exercise and test blood for sugar regularly. Conclusions: The present study concluded that although type II diabetes patients have good knowledge, attitudes, but they lack in practice which is essential to control diabetes.
Anesthesia in a Patient with Stiff Person Syndrome: About A Case
Authors: Bellaka Rabab , Tajellijiti Nissrine , Rhezali Manal , Aboulhassan Taoufiq , Nejmi icham
Published: November 2022

Stiff person syndrome, characterized by stiffness in the muscles of the torso and extremities and painful episodic spasms, is a rare autoimmune neurological disease. Here we present successful endotracheal intubation. A 46- year-old man underwent surgery with ASA-III classification due to necrosectomy following fasciitis necrotizing. After induction of anesthesia using fentanil propofol and rocuronium, tracheal intubation proceeded easily without neuromuscular blockade. Anesthesia was maintained with isoflurane and an O 2 /air mixture. After an uneventful intraoperative period, the patient was extubated. The evolution was marked by death following a septic shock. Although the mechanism is unclear, neuromuscular blockers and volatile anesthetics can cause prolonged hypotonia in patients with stiff-man syndrome.
Crisis of Banditry and the Internally Displaced Persons in Nigeria: A Political Economy Approach
Authors: Brigid Ochi Ijeoma , Boniface Ortindi , Okonkwo Arinze Emmanuel
Published: November 2022

Banditry crisis in Nigeria is one of the reasons for the emergence of the internally displaced persons (IDPs) and the creation of Internally Displaced Persons’ Camps (IDPCs). From the point of view of political economy approach, bandits attack as a result of many factors ranging from poverty and unemployment to the proliferation of arms as well as the desire to belong to the society. Managing this crisis has been difficult for the Nigerian state as adequate attention is not given to the situation; thus the increased number of displaced persons on daily basis. The study made use of secondary sources of data collection. It was discovered that banditry imposes untold hardship on the people; affecting their means of livelihood and exposing them to illegal means of sustenance. It has led to loss of lives and properties, undermined the security, peace and development of the Nigerian state and made women vulnerable to many societal ills. Efforts made by stakeholders to combat the scourge have not yielded the desired result. The paper thus recommends among others that, the over-dependence on the military to fight banditry is not the solution to the menace. There is the need to address the root causes of the banditry crisis which include poverty, unemployment, weak security system, the fragility of the Nigerian state, proliferation of arms and corruption. The government therefore should provide job opportunities for the youths; a conducive environment for the Internally Displaced Persons and plan ahead for them to return to their various homes. The government also should effectively monitor and secure the Nigerian borders with the neighbouring countries to checkmate illegal migration of people and arms proliferation. The government should re-orientate the people on ethical values and reverence for life and human rights.
Taurochotine Drug Design as Sodium Taurocholate Co-Transporting Polypeptide (NTCP) Inhibitor for HBV Treatment, in Silico Approach
Authors: Mohammed Mohammed Y. , Khaier Mona Abdelrhman Mohamed , Agabna Nuha , Shaddad Sania A.
Published: November 2022

Background: Hepatitis B Virus (HBV) is a viral infection that attacks the liver and can cause both acute and chronic disease. The virus is most commonly transmitted from mother to child during birth and delivery. Also, by contact with patient blood or other fluids during sex with an infected partner. The virus enters the cell body by sodium taurocholate cotransporting polypeptide receptor (NTCP), then it replicate and invade other healthy cells. Aim: the aim of this study is to design a drug that can block sodium taurocholate cotransporting polypeptide receptor (NTCP), Using bioinformatics tools and servers. Material and method: Using CHemSketch the drug molecule was drawn and determined and using OpenBabel software the molecule was transferred and designed into MOL 2 format to be applied in the SwissDock server. The target protein from the protein database bank using the PDB ID of NTCP receptor protein was retrieved and then inserted it into SwissDock. The result of docking was then subjected to SwissADME to check the pharmacological effect. Results: A novel drug that can inhibit and block sodium taurocholate cotransporting polypeptide receptor (NTCP) hence can treat the HBV. Conclusion: With these predicted pharmacokinetics and chemical properties of NTCP inhibitor, a new emerging drug to treat hepatitis B virus disease, which affects the majority of people around the world, especially in poor countries, can be developed, and this can be achieved with more research and laboratory procedures.
Emprendimiento e innovación en el contexto de la crisis sanitaria
Authors: Giraldo Duque Cesar Augusto , Wilches Martínez Cesar Alberto
Published: November 2022

El proyecto investigativo sobre “emprendimiento e innovación en el contexto de la crisis sanitaria”, es el resultado de un esfuerzo conjunto entre los estudiantes de contaduría pública IIPA 2020 del cuarto semestre tarde y noche del CADI “pensamiento administrativo”, quienes debían realizar propuestas de reactivación económica para los pequeños productores de las fincas que se han visto afectados por la pandemia y no han podido comercializar los productos cosechados. En el proyecto también se tiene en cuenta aquellos productos que no cumplen con los estándares de calidad para ser llevados a un mercado y terminan perdiéndose en las fincas sea por su tamaño, por defectos, picaduras de insectos o dañados en la recolección y mediante un proceso de revisión y desinfección se procede a reutilizar esta materia prima para transformarla en un producto limpio y de buena calidad que puede ser llevado a los mercados. En este documento se puede encontrar varias propuestas que los estudiantes realizaron para transformar los productos perecederos en productos para consumo y venta, a la vez se hace una breve descripción de estos, se definen los tipos de cultivo donde se producen, se presenta fichas técnicas que permite al lector conocer la tabla nutricional y vitamínica del producto en proceso y producto terminado, se presenta un diagrama de flujo con el paso a paso de la transformación de los productos y una hoja de costos que permitirá al campesino conocer el valor real y las ganancias de cada una de sus creaciones.
Emprendimiento, innovación e investigación en tiempos del Covid – 19
Authors: Giraldo Duque Cesar Augusto , Wilches Martínez Cesar Alberto
Published: November 2022

Este libro, titulado Emprendimiento, innovación e investigación en tiempos de covid-19, es el resultado de la investigación realizada en el programa de Contaduría Pública de la Facultad de Ciencias Administrativas, Económicas y Contables, sobre la cultura emprendedora e investigativa en las regiones de la sabana occidental, central y norte del departamento de Cundinamarca. Las actividades desarrolladas el primer semestre del año 2021 involucraron a diferentes actores durante el sector productivo localizados en los municipios ubicados en las regiones mencionadas, así como a la academia, especialmente a estudiantes y profesores.
Diferencias entre la fenomenología de Wittgenstein y la fenomenología de Husserl
Authors: Canela Morales Luis A.
Published: November 2022

Las principales obras de Wittgenstein en las que aparecen con más frecuencia las referencias al concepto de fenomenología (Phänomenologie) son las Observaciones filosóficas (1929-1930), la Gramática filosófica (1931-1934) y The Big Typescript (1933-1934). No obstante, se antoja necesario hacer la precisión de que el uso wittgensteiniano del concepto fenomenología no parece estar vinculado a la tradición fenomenológica husserliana. En este sentido, el objetivo principal de este escrito no será una simple determinación exegética de cuáles son las intenciones filosóficas de uno y otro (de Husserl y Wittgenstein), sino una revisión pormenorizada del papel que juega el concepto de fenomenología en ambos autores y surelación con el concepto de gramática.
How to conduct research into history by assembling certainties
Authors: Ariso José María
Published: November 2022

José Ortega y Gasset relied on his notion of ‘belief’ to argue that historical studies should consist, above all, in assembling the distinctive and characteristic beliefs of a historical period: for, in this way, we could know what was regarded as reality within that context, which might allow us to gain a better understanding of the historical events under study. As I will show in this paper, Ludwig Wittgenstein did not evince an interest in historical studies; yet his notion of ‘certainty’ is very similar to Ortega y Gasset’s conception of ‘belief’, in addition to which certainty in Wittgenstein’s sense may be of great help to better understand not only how historical studies can be conducted by following Ortega y Gasset’s suggestions, but also which risks are entailed bysuch studies.
Fray Luis de León sobre la articulación antropológica de dominio y propiedad
Authors: Zorroza Idoya
Published: November 2022

Partiendo de la interpretación unitaria de la obra de fray Luis de León desde dos claves: pensamiento cristológico y onomástico (aportadas por Saturnino Álvarez Turienzo), se revisan los breves lugares en que este autor aborda la relación entre el dominio natural del ser humano sobre los bienes creados y la división de la propiedad. Fray Luis sigue las tesis de la Escuela de Salamanca sobre la concepción del dominio como atribución a la misma naturaleza humana y las múltiples formas de propiedad que derivan del derecho positivo, pero vincula al derecho de gentes (tradicionalmente ejemplificado con la división de la propiedad) un desarrollo propio y específico.
Persona
Authors: Sarrión Cayuela José
Published: November 2022

Cegados por un mundo cuyo relato se centra en la búsqueda del progreso científico-técnico es fácil caer en la tentación de reducir, por insignificante, cualquier otro tipo de saber. Pero la realidad es otra. El reduccionismo en el que se instala este planteamiento como si fuera un dogma cerrado sobre sí mismo, nos da las claves de las consecuencias nefastas en las que sobrevive la mayoría de esta sociedad. Con estos planteamientos de sobredimensionarlo científico-técnico no se sigue una sociedad más justa. Además de este hecho, es posible que la actitud de la sociedad se divida entre quienes noquieren cambiar los paradigmas que siempre funcionaron para una parte de los más prepotentes y económicamente fuertes de la sociedad (una décima parte de la población en el mejor de los casos) y entre aquellos que luchan por lograr la supervivencia a base de una capacidad de adaptación a lo económicamente posible, austero y socialmente más significativo.
Wittgenstein's idealism
Authors: Tana Guido
Published: November 2022

The following contribution aims at presenting a reading of Wittgenstein’s later philosophy as a kind of idealism within the Kantian and post-Kantian tradition. The goal is to argue that Wittgenstein’s position shares substantial theoretical and methodological grounds with Hegel’sidealism. The main concepts pertaining to the later Wittgenstein’s position are analyzed and understood as a form of idealism. After defending the reading against anti-idealist interpretations we argue that the kind of idealism presented clashes with central tenets of the Kantian position.These points of departure are then shown to cover in substantial manner the same kind of criticism Hegel raised against Kant. In the last section, an interpretation of central concepts of the Hegelian position is offered in order to dissolve any fundamental incompatibility with Wittgenstein’s idealism.
Beatitud y autorealización
Authors: Blesa Aledo Belen
Published: November 2022

¿Qué conexión podemos hallar entre la beatitud en Spinoza y la investigación sobre la autorrealización en Maslow? Y, en términos más concretos, ¿en qué se parecen la persona sabia y la persona autorrealizada? Este trabajo intenta dar consistencia a estas preguntas. Para trazar el arduo recorrido que supone aproximar obras tan aparentemente distantes, adoptamos como hipótesis que ambos autores se remiten a un tipo de experiencia relacionada con la vida plena. Ésta se concibe como un proceso sin finalidad, centrífugo y articulado en un conocimiento de nuestra naturaleza. La vida plena nos sitúa en la realidad, es gratificante en sí misma y desafía diferentes modalidades de ignorancia. La experiencia de plenitud parte del esfuerzo natural por ser lo que somos y se expresa en el desarrollo de nuestra potencia vital, a la que acompaña un afecto edificante y alegre. El artículo no busca hacer una comparativa, algo fuera de lugar dadas las diferencias contextuales, conceptuales y de estilo entre los autores. Su aspiración es mostrar algunas sinergias sin crear una tensión innecesaria.
Del reconocimiento del Dios del amor a los conceptos de religión y resurrección de la carne en Miguel de Unamuno
Authors: Aparicio Marcos Arrate
Published: November 2022

El presente artículo tiene como objetivo dar a conocer la lucha interna que mantuvo Miguel de Unamuno entre su razón y su fe, lo que repercute en su confusa búsqueda del Dios de la razón y, consiguientemente, su reconocimiento del Dios del amor. De esta suerte nos adentraremos en su concepción de religión y resurrección de la carne, que nos hará determinar que la historia que nos une como cristianos es historia de amor. Todo ello queda enriquecido por notas inéditas sobre el tema, escritas por Unamuno y localizadas en su Casa-Museo de la Universidad de Salamanca
mano
Authors: Borges de Meneses Ramiro Delio
Published: November 2022

La mano realiza rituales y trabajos, felicita a alguien por los cumplidos, trepa al cielo, toca instrumentos, escribe y hace lectura. La mano será el órgano de lenguajes polisémicas de toda la naturaleza, como lo revela la Anatomía y Fisiología. Con este artículo, pretendemos construir una fenomenología de la instrumentalidad, que incluye diferentes significados, tales como: ética, teología y religión, en busca de una fenomenología nueva de la quiralidad, que esclarezca los aspectos importantes de las apariencias de las manos
Filosofía: ¿Elucidación o teorización?
Authors: Rodríguez Ortiz Angélica María , Arango Restrepo Gabriel Jaime
Published: November 2022

El texto hace una revisión crítica de los apartados del libro Perspectivas wittgensteinianas. Lenguaje significado y acción (2021), a partir de la visión de la filosofía presente en las investigaciones de Ludwig Wittgenstein, para quien todo intento de teorización constituye un intento inútil de salir de un atolladero. Por ende, la responsabilidad de la filosofía radica en la aclaración, mediante el análisis del lenguaje, de las quimeras conceptuales que ella misma ha creado. Se abordan los temas de la inviabilidad de la teoría del color en términos lógicos, el carácter no epistémico de las proposiciones gozne y de las creencias religiosas, la objetividad como criterio dentro de un sistema de reglas, la vaguedad del lenguaje y el giro pragmático.
Guía de viaje para recorrer la filosofía antigua
Authors: Román Alcalá Ramón
Published: November 2022

Reseña de: ILDEFONSO MURILLO, Historia de la filosofía antigua, Sapientia rerum.serie de manuales de filosofía, Biblioteca e Autores Cristianos, Madrid, 2021, 328 págs
Hegel and Wittgenstein
Authors: Macha Jakub
Published: November 2022

I argue that Hegel and Wittgenstein, each in their own specific way, used the idea of God at the beginning of creation as a complex analogy for other kinds of beginning, most notably the beginning of philosophical thought. Hegel’s Logic describes God’s mind before the creation of the world, i.e. God’s pure thinking. For a philosopher, beginning afresh means resolving to consider this kind of abstraction from the existence of the world. Wittgenstein, by contrast, says that the idea of a creator of the world does not explain anything. It marks the terminus ad quem of asking for explanations; we must not ask further who created the creator of the world. Wittgenstein generalizes this for any kind of reasoning: “Explanations come to an end somewhere.” (PhilosophicalInvestigations: §1) Any sort of explanation must eventually arrive at its terminus ad quem, which means only that any kind of reasoning must have its logical beginning.
THE VIABILITY OF LEUKOCYTES AND REACTIVE OXYGEN SPECIES GENERATION BY THEM IN RATS WITH CHRONIC COLITIS
Authors: Babenko Olha , Vasylyeva Irina , Nakonechna Oksana , Popova Liudmyla , Voitenko Stanislav , Pustova Nataliia
Published: November 2022

The aim: To assess reactive oxygen species production by leukocytes and their viability in rats with chronic colitis.
Materials and methods: Reactive oxygen species production was estimated in leukocytes, isolated from rats with Dextran Sulfate Sodium-induced chronic colitis and control rats, by flow cytometry using the fluorescent probe 2’,7’-dichlorodihydrofluorescein diacetate. Leukocyte viability and apoptosis stages were assessed by flow cytometry using annexin V and 7-aminoactinomycin D staining. White blood cell counting was carried out with using Hematology Analyzer.
Results: The increased fluorescence intensity of 2’,7’-dichlorofluorescein in viable leukocytes by 36.7% was revealed in rats with chronic colitis compared control rats. A significant decrease in the percentage of viable cells and an increase in apoptotic cells were found compared to intact animals. Leukocytes, granulocytes, monocytes, lymphocytes counts in blood of experimental group animals were significantly higher compared to control those.
Conclusions: Our findings indicate that Dextran Sulfate Sodium-induced chronic colitis increases an intracellular production of reactive oxygen species by leukocytes. Despite of increased leukopoiesis it reduces viability of white blood cells and promotes their apoptosis via stimulation of oxidative stress.
Inclusión digital para estudiantes universitarios con discapacidad visual
Authors: Escobar-Morales Gabriel , Elizondo-Quintanilla Ingrid. L. , García-Mirón Jessica Patricia , Carranza-Padilla María José
Published: November 2022

Las personas con discapacidad visual son un grupo de la población que ha sido altamente vulnerado en la garantía de sus derechos humanos, incluyendo el de la accesibilidad a la información. En la era digital, la brecha de la desigualdad se acrecienta para aquellas personas que se les dificulta el acceso a las tecnologías de la comunicación e información, aún en contextos educativos. En este artículo se presentan los resultados del proyecto de investigación "Inclusión Digital de Personas con Discapacidad Visual en la Educación Superior", cuyo objetivo principal fue una exploración para determinar los avances en la inclusión digital de los estudiantes con discapacidad visual en su formación educativa a nivel superior. Para ello, se utilizó una metodología con enfoque mixto de investigación, en donde la muestra la constituyeron 26 estudiantes con discapacidad visual de la Universidad de San Carlos de Guatemala (USAC), del ciclo 2020, de unidades académicas ubicadas en el Campus Central y Centro Universitario Metropolitano. También se contó con la participación de 113 docentes y 32 trabajadores de bibliotecas o centros de documentación. En los resultados se evidencia que las bibliotecas o centros de documentación juegan un papel preponderante, desde contar con materiales bibliográficos en formatos alternativos o accesibles, así como la importancia de que las propias administraciones o dirigentes académicos deben sumarse con esfuerzos de recursos humanos, financieros y de otra índole para implementar las herramientas tecnológicas y de inclusión digital accesibles para la formación educativa superior de las personas con discapacidad visual en la USAC.
Dibujos y pinturas de Rafael Cuevas Molina
Authors: Cuevas Molina Rafael
Published: November 2022

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The Concept of Spiritual Leadership in Educational Institutions is Based on Maqashid Shari'ah
Authors: Rahmatika Arivatu Ni'mati , Ma'arif Samsul , Wahid Abd , Kusuma Kamelia Evi
Published: November 2022

The purpose of this study is to find out a new concept of spiritual leadership based on Maqashid Syari'ah in educational institutions. This research uses a qualitative approach that uses literature studies and content analysis techniques. Spiritual leadership in educational institutions has three concepts, namely, assuming a leader has leadership traits since birth, group function is seen as leadership because the success or failure of a leader depends on how the group works and making concepts that are more advanced and better. This study also shows that leaders need to understand the importance of vision, altruistic love, and the expectations of members in leadership. The net result of the concept of spiritual leadership in educational institutions based on maqashid shari'ah must adjust to five forms of protection, namely, religious protection, protection of life, protection of property, protection of reason, and protection of lineage. From this form of protection, leadership in educational institutions will be more practical, structured, and consistent. After doing literature research by analyzing spiritual leadership based on maqashid shari’ah, it can be concluded that the content of the concept of spiritual leadership is by the protection in maqashid shari’ah". structured and consistent. After doing literature research by analyzing spiritual leadership based on maqashid shari’ah, it can be concluded that the content of the concept of spiritual leadership is by the protection in maqashid shari’ah". structured and consistent. After doing literature research by analyzing spiritual leadership based on maqashid shari’ah, it can be concluded that the content of the concept of spiritual leadership is by the protection in maqashid shari’ah.
AZƏRBAYCANDA PALÇIQ VULKANLARININ NEFT VƏ QAZ OBYEKTLƏRINƏ TƏHLÜKƏLI VƏ UNIKAL TƏZAHÜRÜ KIMI
Authors: İftixar Qasımov İftixar Qasımov
Published: November 2022

Tədqiqat rayonu palçıq vulkanlarının öyrənilməsinə həsr edilmiş elmi-tədqiqat işləri müəlliflərinin məlumatlarına əsaslanaraq qeyd edə bilərik kı, palçıq vulkanları əsasən Azərbaycan bölgəsini istifadə edərək, palçıq vulkanlarının fəaliyyətinin kəmiyyət qiymətləndirəsini apardıq. Palçıq vulkanlarının püskürmələrinin orta illik sayı 0.9‒1 % təşkil edir. Həmin ərazilər üçün palçıq vulkanı püskürmələrinin kataloqlarının 26 % tamamlandığını təxmin edirik, müvafiq olaraq palçıq vulkanlarının püskürməsi olduqca tez-tez baş verir. Hər iki bölgədə qeydə alınan bütün püskürmələrin 50%-dən çoxu son püskürmədən sonra on il ərzində baş verir.
Açar sözlər: palçıq vulkanı, seysmik, ekstrapolyasiya, zəlzələ, təzahür, emissiya, püskürmə, yataq.
PRODUCT QUALITY MANAGEMENT AT THE ENTERPRISE IN THE CONDITIONS OF UKRAINE’S ENTRY INTO THE EU
Authors: TOMASHUK Inna
Published: November 2022

The peculiarities of the concept of Total Quality Management (hereinafter – TQM) in the activities of domestic enterprises in the conditions of the implementation of the European development vector of Ukraine were studied. It is indicated that the guarantee of the enterprise's activity on the basis of sustainability is its competitiveness. It is emphasized that ensuring the proper quality of the performed works and services is one of the important tasks that are solved at the enterprise within the framework of management activities.

Attention is focused on the fact that in modern conditions of economic development, quality is a general set of characteristics of products (work, services), which are part of (are a component of) marketing, development, production and maintenance, with the help of which products (work, service) must meet needs at a price the consumer can afford.

Quality management is defined as a continuous process of influencing production through the consistent performance of logically interrelated functions to ensure product quality. It has been investigated that effective management of the quality of goods, works and services can be ensured by creating a quality management system at the enterprise.

It is noted that today in quality management at the enterprise, a certified quality management system is important, which is a guarantee of high stability of quality characteristics of products, goods and services. The quality system certificate allows the enterprise to maintain a competitive advantage in the market.

It was emphasized that a significant impetus for the creation of international standards of the ISO 9000 series can be considered a significant increase in consumer demands for product quality.These requirements are regulated by relevant regulatory documentation (standards, technical conditions and regulations).

It is noted that the quality management process should cover all the stages of production. It is indicated that, regardless of the direction of the activity of the business entity, the quality policy declared by the top management of the enterprise must ensure such a level of quality that guarantees the optimal profit of the enterprise. Ways to achieve this goal can be different and are determined by the general market strategy of the enterprise.

It was concluded that modern quality management at the enterprise, regardless of the forms of ownership and scale of production, should optimally combine actions, methods and means that ensure, on the one hand, the production of products, goods and the provision of services that meet the current requirements and needs of the market, and on the other hand, the development of new products capable of meeting future market demands and needs.
Extensive Tinea Infection in a Post Covid 19 Patient of Type 2 Diabetes-A Case Study
Authors: Chandra Kumar Prafull
Published: November 2022

Introduction: Dermatophytes are the most common agents of superficial fungal infections worldwide, and especially widespread in the tropical and subtropical countries like India, where the environmental temperature and relative humidity are high. Corona virus disease-2019 (COVID-19) likely increases the risk for fungal infections because of its effect on the immune system and because the treatments for COVID-19 (like steroids and other drugs) can weaken the body’s defenses against fungi. The present case discusses extensive Tinea infection in post COVID-19 patient living with Type-2 Diabetes Mellitus (T2DM).

Case presentation, diagnosis, and management: A 58-year-old male with history of T2DM for 27 years presented with progressively increasing skin lesions on his back, gluteal area and back of thigh over 2 months duration. Around 3 months back, he had developed RTPCR positive COVID-19 infection with involvement of lower respiratory tract with dip in peripheral oxygen saturation (SpO2). During hospitalisation, he received deflazacort 30mg once daily along with symptomatic treatment as per contemporary guidelines. At the time of presentation, the lesions were maculopapular with pigmentation and scaling. There were no definite ring lesions with central clearing, which is usually seen in fungal superficial skin infections. Few pustular lesions were also present in genital area.

Nearly one month after discharge slightly elevated circular scaly lesions on his thighs with minimal itching developed which progressed involving back of thighs, gluteal areas, and the back. Diagnosed as Psoriasis, local steroid ointment along with Fexofenadine (antihistamine) was used. There was initial improvement in lesion and symptoms, however there was a flare up in lesion within 2 weeks and several satellite lesions appeared on all over back and gluteal region. Direct microscopic examination of scrapings from the skin lesion after treatment with 20% potassium hydroxide (KOH) was done. The scrapings were characterized by presence of refractile, long, smooth, undulating, branching, and septate hyphal filaments with or without arthroconidiospores confirming the diagnosis of dermatophytosis. Patient was put on local luliconazole 3% cream as it has anti-inflammatory properties along with strong antifungal effect. Looking at the extensive nature of his lesion, he was also started on systemic antifungal Itraconazole 200mg per day for 8 weeks. His insulin doses were modified to achieve a better glycaemic control while avoiding hypoglycaemic events.

Conclusion: Tinea corporis is a common fungal infection and the differential diagnosis is broad and, at times, difficult due to the prior use of medications, such as calcineurin inhibitors or corticosteroids. Furthermore, diseases may present with bizarre morphology in immunocompromised patients. Physicians must be familiar with this condition so that an accurate diagnosis can be made, and appropriate treatment initiated.
A Case Report on Uncontrolled Arterial Hypertension as an Underlying Cause of Conn´s Syndrome
Authors: Martinez José Israel Sánchez
Published: November 2022

A 24-year-old woman who consulted for uncontrolled high blood pressure. Four years ago, was diagnosed with high blood pressure and was treated with many medications without achieving adequate control. On treatment with irbesartan, hydrochlorothiazide, amlodipine. Patient has not family history. Blood pressure of 180/110mmHg was found upon evaluation. Examinations showed evidence of hypokalemia and normal renal function. Chest X-rays and electrocardiogram were normal. Ultrasound Doppler of renal arteries without alterations. Blood aldosterone was measured with values of 22ng/dl and an abdominal tomography showed the presence of a left adrenal adenoma. Spironolactone was orally given at a dosage of 25mg every day, titration every week, reaching a dose of 100mg every day, an education plan with a salt-restricted diet and adequate physical activity was provided. So, it is concluded that Primary aldosteronism is the primary endocrinological cause of secondary hypertension and only 30% of patients have hypokalemia.
Perspectives of Anesthesiologists Towards the Use of Artificial Intelligence in Anesthesia Practice in a Developing Country
Authors: Ejikem Mazpa
Published: November 2022

Objective: Several aspects of healthcare have seen tremendous growth with the help of artificial intelligence (AI). Anesthesiology has not been left out with a remarkable increase in the application of AI in recent times. The aim of this study was to explore the perspectives of anesthesiologists in a developing country on the use of AI in their practice.

Methods: An online survey was carried out and the survey included questions on sociodemographic data, knowledge, opinion, and concerns on the use of AI in their practice. 44 responses were received and analyzed.

Results: A large majority (88.6%) of anesthesiologists had heard about AI but only 6.8% considered themselves to have sufficient knowledge on AI. 68.2% of respondents agreed that AI has useful applications in anesthesia practice, and 56.8% believed that AI would lead to drastic changes in their field. Only a minority of respondents believed that AI abilities will surpass the clinical abilities of human anesthesiologists (13.6%), and that AI will completely replace anesthesiologists in the future (6.8%). There was a significant association between duration of practice and the opinion that AI had useful application in anesthesia practice, as well as between awareness of AI and the opinion that AI abilities are currently superior to the clinical experience of human anesthesiologists.

Conclusion: Anesthesiologists do not have sufficient knowledge of AI, and while they are open to applying AI to their practice, anesthesiologists do not expect AI to replace physicians in their practice.
Fentanyl Patch Overdose-Case Report
Authors: Reinfeld Howard B
Published: November 2022

Fentanyl was introduced more than 50 years ago. It has become the most often used opioid for intraoperative analgesia. Since the early 1990s the fentanyl patch has been available for management of chronic pain of all forms of cancer as well as the persistent, intense pain from many noncancerous maladies. Fentanyl is inexpensive to synthesize and prepare for the marketplace and is now familiar to clinicians working in pain and perioperative medicine throughout the world. Fentanyl has also become popular for illicit use and commonly being combined with other drugs and many overdose cases have been reported.
Festival Innovation in Times of Crisis
Authors: Rentschler Ruth , Lee Boram , Subramaniam Nava
Published: November 2022

This article examines innovation in times of festival crises from a governance perspective using legitimacy theory. We conduct a case study of Adelaide Festival around three crises based on data drawn from annual reports, festival programs, and media articles from 1960 to 2021. Each
crisis raises questions about the need to innovate, whether due to economic concerns or for new approaches to artistic programming, in order to safeguard legitimacy. However, the type of innovation varies based on internal and external environmental factors. Findings reveal tensions ranging
from internal board and external stakeholder use of governance mechanisms, depending on the crisis and perceptions around art forms (e. g., elitism and Aboriginality). The findings provide insights on how appropriate use of governance mechanisms can help to balance tensions between maintaining
legitimacy and promoting innovation. Innovation, nonetheless, did not reposition the festival in the long run: it remains elitist, compromising artistic vision.
Appraisal of Apartments in Albania using Hedonic Regression
Authors: Nurja Ines , Jaupi Fatma , Elezaj Ogerta
Published: November 2022

Valuation of property is an important part of the land organization framework since it has a direct impact on people’s lives. The adjustments within the property estimation can dramatically change the abundance of the organizations and their ability for development. A variety of people may benefit from a better property valuation framework in our society because it reduces the risk of investing in this division and encourages lower interest rates on loans. The aim of this paper is to empirically demonstrate that, aside from location and address of properties, there are other major factors that influence the price of flats in Albania by developing a hedonistic pricing model. The capital city of Tirana and also Durres were selected for this research paper in order to develop a hedonic price model based on the data collected by properties sold at one of the largest real estate agencies, “Century 21” in the country. According to the findings, apartment attributes such as area of living, number of bedrooms and other factors influence the price. The findings also revealed the marginal influence of the number of apartment spaces, which was dependent on the living area of the apartment. This is the first empirical study to present the results obtained from a hedonic regression built using data pertaining to Albania.
estudio longitudinal y coeducativo aplicado a contextos educativos
Authors: Sánchez Reig Dámaris , Turpin Gil Aarón
Published: November 2022

El presente trabajo de investigación pretende realizar un estudio cuasiexperimental longitudinal, tomando como muestra el alumnado de 3º y 4º del Grado de Maestro Educación Primaria del año 2016 y 2022, todo ello con el objetivo de analizar la visión que tienen de la inclusión de la mujer científica. De esta comparativa, se establece una correlación que interconecta con la progresión del marco legislativo vigente durante sendos periodos, dando como resultados la clara importancia de la evolución legislativa para la promoción de una visión más inclusiva hacia la mujer en relación con su capacidad de acceso a las áreas STEM.
periodismo como elemento esencial en el cine de Woody Allen
Authors: San José-De la Rosa Cristina , Gil-Torres Alicia
Published: November 2022

La cinematografía de Woody Allen incluye memorables episodios periodísticos que merecen la atención investigadora para descubrir cómo los medios de comunicación marcan el ritmo de la trama en numerosas escenas de sus películas de los últimos años. Además de masas de periodistas detrás de un famoso o en ruedas de prensa, también hay personajes principales como las periodistas de Scoop (2006) y de A Rainy Day in New York (2019). Este trabajo se inspira en métodos que buscan descomponer al personaje, para lo que se ha optado por las líneas de los autores Casetti y Di Chio. En las 15 películas analizadas se detecta que en el 80% aparecen momentos periodísticos.
Quantitative and qualitative evaluation of the use of nonsteroidal anti-inflammatory drugs in the Russian Federation over 10 years
Authors: Syraeva G. I. , Kolbin A. S. , Mishinova S. A. , Kalyapin A. A.
Published: November 2022

Relevance. Studies devoted to the assessment of consumption, as well as to the issues of pharmacosafety of nonsteroidal anti-inflammatory drugs, are limited at the national level in the Russian Federation. The study of these issues will determine the general trends of consumption and prescription of this group of drugs.

Aim. To assess the consumption pattern of NSAIDs in the Russian Federation in the period from 2010 to 2020.

Methods. Information was searched using data from the state register of drugs (GRLS) as well as national database downloads (automated information system of Roszdravnadzor; AIS RZN). To estimate the consumption of the main INN from the group of NSAIDs for the period 2010–2020 the information on the sales volume of all trade names, sold for sale in the Russian Federation was unloaded from the database of IQVIA Solutions Ltd. and analyzed.

Results. The analysis showed that the first place by total amount of consumption was occupied by acetylsalicylic acid (5 953 058 854); second place — paracetamol (4 635 122 085); third place — ibuprofen (3 230 415 088); fourth place — metamizole (4 172 344 008); fifth place — ketorolac (91 617 809,04); sixth — nimesulide (69 761 7481,8). The claimed INNs showed a slightly different distribution when calculating the DDDs/P (patient-year) totals, namely, in descending order, nimesulide, ketorolac, ibuprofen, acetylsalicylic acid, paracetamol, and methamisole.

Conclusion. The indicated levels of consumption do not correlate with the data of the national database “Pharmacovigilance”, which indicates insufficient post-marketing monitoring of the safety profiles of the indicated medicines.
The use of a new oral antiviral drug molnupiravir in the treatment of COVID-19 from a safety perspective
Authors: Khokhlov A. L. , Rybachkova J. V.
Published: November 2022

Molnupiravir is an antiviral drug with a broad spectrum of activity against RNA viruses. The safety of molnupiravir in clinical trials with COVID-19 was analyzed. In a Phase I study (NCT04392219), molnupiravir was well tolerated at doses of 50 to 800 mg twice daily for 5.5 days and at single doses up to 1600 mg. Common adverse events were headache (18.8 % placebo versus 12.5 % molnupiravir) with a single dose and diarrhea (7.1 % in both groups) with multiple doses. In a phase II study in the molnupiravir 800 mg group, adverse events were noted in the form of headache, insomnia, and an increase in the level of alanine aminotransferase. Serious adverse events leading to hospitalization occurred in the placebo group (1.6 %) due to hypoxia, in the molnupiravir 400 mg group in two (3.2 %) participants due to cerebrovascular accident and in one (1.8 %) of a participant at a dose of 800 mg due to acute respiratory failure. In the phase III MOVe-OUT study (NCT04575597), adverse events were reported in 30.4 % in the molnupiravir group and 33.0 % in the placebo group. In the phase III study CTRI/2021/06/033992, adverse events occurred in 6.5 % in the molnupiravir group versus 8.9 % in the placebo group. The results of the conducted studies demonstrate the safety, tolerability of molnupiravir in phase I, II and III clinical trials and the antiviral efficacy of the drug against COVID-19. Use of molnupiravir for mild to moderate (SpO2 > 93 %) COVID-19 within 5 days of symptom onset significantly reduces disease progression by reducing hospitalizations and/or deaths.
Polypharmacy problems in geriatric practice of Kyrgyz Republic
Authors: Sharaeva A. T. , Zurdinova A. A.
Published: November 2022

World statistics shows increasing numbers of aging population and increasing number of patients with multiple comorbidities, i. e. polymorbidity, which today is an urgent problem of modern clinical geriatric practice. During clinical examination of elderly and senile patients, at least 4-5 diseases and manifestations of pathological processes are diagnosed on the average. Because of this many medicines are prescribed to elderly patients at the same time, unfortunately, often unreasonably, which becomes a widespread phenomenon and is called polypharmacy. Polypharmacy is associated with an increased risk of adverse reactions that can lead to hospitalization or even death, as well as a significant increase in health care costs.

In this regard, an analysis of medication prescribing in elderly inpatients with cardiovascular disease using the Medication Rationality Index (MAI) was conducted. As a result, it was found that professionals who provide care to patients are not sufficiently aware of the peculiarities of the use of drugs in elderly patients and in our health care sector there are no regulatory documents on the care of elderly patients.