bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Design, Synthesis, and Urease Inhibition Studies of a Series of 4‐Amino‐5‐aryl‐3H‐1,2,4‐triazole‐3‐thiones.
Authors: Khan Mahmood‐ul‐Hassan , Hameed Shahid , Yasin Khawaja A. , Akhtar Tashfeen , Khan Khalid M.
Published: September 2010

Title compounds (III) are screened for urease inhibition activity.
ChemInform Abstract: Photoinduced Reactions: Phototransformations of 2‐Aryl‐3‐(methoxymethoxy)chromones.
Authors: Kamboj Ramesh C. , Thakur Mandeep , Berar Surinder , Berar Urmila , Siddiqui Zeba N. , Gupta Satish C.
Published: September 2010

The photochemical behavior of the 2‐aryl substituted chromones (I) and (VI) respectively is studied and the product formation is explained on the basis of type‐II hydrogen abstraction by the excited carbonyl function.
ChemInform Abstract: Efficient, Mild and Completely Regioselective Synthesis of Substituted Pyridines.
Authors: Andersson Hans , Sainte‐Luce Banchelin Thomas , Das Sajal , Olsson Roger , Almqvist Fredrik
Published: September 2010

The addition of Grignard reagents to pyridine N‐oxides followed by treatment with TFAA leads regioselectively to the corresponding 2‐substituted pyridine derivatives.
ChemInform Abstract: A New General Approach to 4‐Substituted‐3‐halo‐2‐quinolones
Authors: Zhao Shuai , He Yan‐hong , Wu Di , Guan Zhi
Published: September 2010

via intramolecular Horner—Wadsworth—Emmons olefination of halogen‐containing N‐acyl‐o‐aminophenyl ketones (III) (18 examples)
ChemInform Abstract: Retro‐Claisen Condensation versus Pyrrole Formation in Reactions of Amines and 1,3‐Diketones.
Authors: Deb Indubhusan , Seidel Daniel
Published: September 2010

Optimized conditions are developed to provide fused pyrrole skeletons.
ChemInform Abstract: Synthesis and Properties of 3,6‐Diamino‐Substituted 1,2,4‐Triazin‐5(2H)‐ones.
Authors: Geffken Detlef , Koellner Maria Anna
Published: September 2010

The ultrasound‐promoted cyclocondensation of guanidines (I) with 2‐amino‐2‐thioxoacetate (II) leads to the novel title triazinones (III) (7 examples).
ChemInform Abstract: Rare‐Earth Activated Nitride Phosphors: Synthesis, Luminescence and Applications
Authors: Xie Rong‐Jun , Hirosaki Naoto , Li Yuanqiang , Takeda Takashi
Published: September 2010

Review: 51 refs.
ChemInform Abstract: Montmorillonite K‐10: As a Useful Catalyst in Organic Preparations.
Authors: Baghernejad Bita
Published: September 2010

Review: 96 refs.
ChemInform Abstract: Luminescent Organoboron Conjugated Polymers
Authors: Nagai Atsushi , Chujo Yoshiki
Published: September 2010

Review: 109 refs.
ChemInform Abstract: Friedel—Crafts‐type Cyclizations
Authors: Hayashi Ryuji , Cook Gregory R.
Published: September 2010

Review: 212 refs.
ChemInform Abstract: Cyclizations Based on C—H Activation
Authors: Capretto David A. , Li Zigang , He Chuan
Published: September 2010

Review: 172 refs.
ChemInform Abstract: Cyclization of Cyclopropane‐ or Cyclopropene‐Containing Compounds
Authors: Zhang Junliang , Xiao Yuanjing
Published: September 2010

Review: 177 refs.
ChemInform Abstract: Transition Metal Catalyzed Cycloisomerizations and Nucleophilic Cyclization of Enynes
Authors: Herrero‐Gomez Elena , Echavarren Antonio M.
Published: September 2010

Review: 298 refs.
ChemInform Abstract: Construction of Eight‐Membered Carbocycles with Trisubstituted Double Bonds Using the Ring Closing Metathesis Reaction
Authors: Tori Motoo , Mizutani Reiko
Published: September 2010

Review: 50 refs.
ChemInform Abstract: Methyltrioxorhenium Catalysis in Nonconventional Solvents. A Great Catalyst in a Safe Reaction Medium
Authors: Crucianelli Marcello , Saladino Raffaele , De Angelis Francesco
Published: September 2010

Review: 105 refs.
ChemInform Abstract: Microwave Accelerated Synthesis of PET Image Contrast Agents for AD Research
Authors: Kallmerten A. E. , Jones G. B.
Published: September 2010

Review: 16 refs.
ChemInform Abstract: Secondary and Primary Amine Catalysts for Iminium Catalysis
Authors: Brazier John B. , Tomkinson Nicholas C. O.
Published: September 2010

Review: 237 refs.
ChemInform Abstract: Biologically Functional Molecules from Mushrooms
Authors: Kawagishi Hirokazu
Published: September 2010

Review: 55 refs.
Interaction of Sulfonated Calix[n]arenes with Rhodamine B and Its Application to Determine Acetylcholine in a Real Neutral Aqueous Medium
Authors: Zhang Yong‐Jun , Cao Wei‐Xiao , Xu Jian
Published: September 2010

Complexation between Rhodamine B (RB) and sulfonated calix [n] arenes (SCnA) were studied by means of UV‐vis spectroscopy and fluorescence spectroscopy. In the presence of sulfonated calix[n] arenes, the absorption band of Rhodamine B shifts to longer wavelength and its intensity decreases. The formation of a host‐guest type complex also results in the fluorescence quenching of Rhodamine B. The association constants for the RB/SCnA complexes increase in the order of SC4A < SC6A < SC8A and show dependence on the size of the cavities of the calixarenes. The fluorescence is selectively regenerated by adding acetylcholine. Based on this observation, a method to determine acetylcholine in a real neutral aqueous medium was developed.
An Electropolymerized Membrane Biosensor for Specific DNA Recognition
Authors: Peng Tu‐Zhi , Cheng Qiong , Yang F. Catherine
Published: September 2010

A sensitive electrochemical biosensor for detecting the sequence of short DNA oligomers is represented. The biosensor is based on a platinum electrode covered a polymerized membrane of conductive monomer N‐[6‐(thien‐3‐yl)acetoxy]‐pyrrolidine‐2, 5‐dione (TAPD). The membrane of TAPD immobilizes a probe DNA on the electrode. The hybridization of the probe with a sequence‐specific DNA in sample solutions is monitored by a self‐synthesized electroactive indicator, which specifically intercalates in the hybrids on the electrode surface. The current signal of the biosensor is proportional to the concentration of the target DNA in samples, and a very low detection limit of 5 × 10−10 mol/L is found. The biosensor has been used to detect the short oligomers containing of HTV‐1 and mycobacterrium nucleotide sequences.
Recent Advances in Organic Reactions Catalyzed by Lanthanide (III) Complexes
Authors: Rui‐Fang Chen , Chang‐Tao Qian
Published: September 2010

Lanthanide compounds have been attracting much attention in organic synthesis. Chiral Ln‐substituted BINOL have been widely studied in several asymmetric organic reactions. LnCl3 and Ln(OTf)3 have been expected to serve as Lewis acids and have been applied to many important synthetic reactions in a one‐pot manner. Ln(O‐i‐Pr)3 exhibits some basic characters, which also can be utilized in some special organic transformation. This article deals with some lanthanides(III) complexes promoted organic reactions, which we have recently developed.
A Novel Octahedral Hexasilver(I) Cluster: Ag6[SSCN(n‐C4H9)2]6
Authors: Zhang Wei‐Guang , Zhong Yun , Tan Min‐Yu , Liu Wei‐Sheng , Su Cheng‐Yong
Published: September 2010

The first crystal structural report of a AgDTC complex (DTC = dialkyldithiocarbamate, R = n‐butyl) presented in this paper shows that it is a hexanuclear species. The structural arrangement for the DDP (dialkyldithiophosphate) ligands is different from that of Cu6(DDP)6, but is the same as that of Ag6‐[SSP(O‐i‐Pr)2]6.
Studies on the Binding Mode of Pinacyanol Chloride to Nucleic Acids
Authors: Wu Hui‐Ling , Li Wen‐You , Miao Kun , He Xi‐Wen , Yu Chun‐Feng , Huang Xi‐Tai , Liang Hong
Published: September 2010

The interaction of pinacyanol chloride (PC) with nucleic acids has been investigated by a series of experiments. Extensive hypochromism, appreciable peak shifts, isosbestic points and new peaks of the product of binding to nucleic acids in the spectra were observed. They showed that the interaction between PC and nucleic adds occurred. The results from absorption spectra of DNA, DNA melting, electrophoresis and fluorescence polarization studies have indicated that PC binds to DNA in nonintercalative way. Consistent with the nonintercalation, the studies of fluorescence titration and absorption titration specified that the binding of PC to nucleic acids occurred by an outside stacking binding, in which nucleic acids served for acting templates. The fact that the new absorption peaks of bound PC at ca. 485 nm are just close to the absorption bands of H‐aggregate of PC at high concentrations without DNA further supports the outside stacking binding mode. In addition, other evidence indicated that the interaction between PC and nucleic acids is not purely electrostatic.
Synthesis of Benzo [a] phenoxazin‐5‐one Derivatives and Their Interactions with DNA
Authors: Zhang Peng , Meng Ji‐Ben , Long Jiang , Matsuura Teruo , Wang Yong‐Mei
Published: September 2010

The spectroscopic properties of benzo[a]phenoxazin‐5‐one derivatives (3a‐3m) including newly synthesized 3k‐3m from 4‐nitrosoaniline hydrochlorides and ethyl 1,3‐dihydroxy‐2‐naphthoate were studied. Compound 31 was converted into a covalent product with DNA, which had a blue shift of the fluorescence maximum. Compounds 3a‐3k were found to undergo interaction with DNA and their complexes with DNA had a red shift of the fluorescence maximum and showed increasing melting temperature of DNA. Compound 3m‐DNA had a blue shift of the fluorescence maximum to 3m and showed decreasing melting temperature of DNA.
Antioxidant Activity of Ecdysteroids from Serratula strangulata
Authors: Dai Jing‐Qiu , Cai Yu‐Jun , Shi Yan‐Ping , Zhang Yong‐Hong , Liu Zhong‐Li , Yang Li , Li Yu
Published: September 2010

One new ecdysteroid, (24R)‐24‐(2‐hydroxyethyl)‐20‐hydroxyecdysone (3), as well as three known ecdysteroids, has been isolated from Chinese herb Serratula strangulata and these compounds 1–4 showed effective antioxidant activity on AAPH‐induced hemolysis of human RBC and Fe2+ + cysteine‐induced lipid peroxidation of liver microsome.
Synthesis, Structure and Reactivity of Lanthanocene Complexes
Authors: Qian Chang‐Tao , Zhu Cheng‐Jian
Published: September 2010

A variety of lanthanocene complexes, e. g. chlorides, hydrocarbyls, amides, hydrides and divalent derivatives, were synthesized by using a series of designed cyclopentadienyl, indenyl and fluorenyl ligands with ring bridges or donor‐functionalized sidearms. X‐Ray crystallographic analyses reveal the formation of intramolecular coordination bonds between central metals and heteroatoms (O, N) in sidearms or bridging chains. Some applications of these complexes are also discussed in this account.
A Triple Cluster Platinaborane: [(P(2)Ph3)Pt(1)(μ2‐B(11)‐(B(9)‐OC(CH3)3‐B10H10))Pt(7)(P(1)Ph3)]2
Authors: Hu Chun‐Hua , Yong Wei , Dou Jian‐Min , Sun Jie , Hu Ke‐Ji , Jin Ruo‐Shui , Zheng Pei‐Ju
Published: September 2010

The title platinaborane, [(P(2)Ph3)Pt(l)(μ2‐B(11)‐(B(9)‐OC‐(CH3)3‐B10H10)Pt(7)(P(1)Ph3)]2, a triple cluster, which is a binuclear Pt complex dimmer, was prepared. Single crystal X‐ray diffraction analysis shows that a Pt(7) atom served as a common vertex between cluster |PtB10| and |Pt4|. The |Pt4| cluster is of parallelogram.
Synthesis of Nanorods of Crystalline Co3O4 Using Carbon Nanotubes as Templates
Authors: Wu Hua‐Qiang , Shao Ming‐Wang , Wei Xian‐Wen , Gu Jia‐Shan , Qu Mei‐Zhen
Published: September 2010

Synthesis of cobalt oxide (Co3O4) nanorods was achieved by templating against carbon nanotubes via wet chemical technique. The products with crystalline structure were mainly composed of Co3O4 nanorods with diameters in the range of ca. 75–100 nm and lengths in the range of 0.12–1 μm, and were characterized by XRD, TEM, SAED and HRTEM.
Enantiomer Separation of α‐Dimethyl Dicarboxylate Biphenyl and Related Biphenyl Compounds by Normal Phase HPLC on Polysaccharide Based Chiral Stationary Phases
Authors: Liu Yue‐Qi , Han Xiao‐Qian , Qi Bang‐Feng , Liu Chun‐Hui , Li Yong‐Min , Chen Li‐Ren
Published: September 2010

Cellulose tris(4‐methylphenylcarbamate), amylose tris(3,5‐dimethylphenylcarbamate) and amylose tris (phenylcarbamate) were prepared by the method reported by Okamoto and were coated onto an aminopropylated mesoporous spherical silica gel. These final products were used as chiral stationary phases of high performance liquid chromatography for the eighteen structurally related biphenyl compounds. The resolution was made using normal‐phase methodology with a mobile phase consisting of n‐hexane‐alcohol (ethanol, 1‐propanol, 2‐propanol or 1‐butanol). The effects of various aliphatic alcohols in the mobile phase were studied. The structural features of the solutes that influence their k′were discussed. A dominant effect of trifluoroacetic acid on chiral separation of acidic solutes was noted.
First Synthesis of Mosquito Larvicidal Butenolides I and II
Authors: Jiang Sheng , Wu Yu‐Lin , Yao Zhu‐Jim
Published: September 2010

Utilizing aldol condensation and β‐elimination as the key steps, butenolides I and II in excellent enantiomeric purity have been concisely synthesized for the first time. According to the rotation difference between synthetic samples and natural products, the rotations were corrected by the calculation upon HPLC measurements. In addition, an efficient way to synthesize methyl pentadec‐14‐enoate was developed.
Flavonoids from Carthamus tinctorius
Authors: Li Feng , He Zhi‐Sheng , Ye Yang
Published: September 2010

Two new flavonoids, (2S)‐4′,5‐dihydroxyl‐6,7‐di‐O‐β‐D‐glucopyranosyl flavanone (1) and 6‐hydroxykaempferol 6,7‐di‐O‐β‐D‐glucopyranoside (2), were isolated from Carthamus tinctorius. Their structures were elucidated by spectroscopic means including 2D NMR, ESIMS and CD.
Microwave‐prompted Reaction of Cinnamonitrile Derivatives with 5,5‐Dimethyl‐1,3‐cyclohexanedione
Authors: Tu Shu‐Jiang , Miao Chun‐Bao , Gao Yuan , Feng You‐Jian , Feng Jun‐Cai
Published: September 2010

In the reactions of α‐cyanocinnamonitrile or β‐cyano‐β‐carbothoxy styrene with 5,5‐dimethyl‐1,3‐cyclohexanedione in the presence of ammonium acetate under microwave irradiation without solvent, the 2‐amino‐5,6,7,8‐tetrahydro‐5‐oxo‐4‐aryl‐7,7‐dimethyl‐4H‐benzo‐[b]‐pyran derivatives were obtained. However, in the reactions of arylidenecyanoacetamide with 5,5‐dimethyl‐l,3‐cyclohexanedione under the same reaction conditions, the acridine derivatives were obtained. The structures of the products were determined by single crystal X‐ray diffraction analysis.
A New Denoising Technique for Capillary Electrophoresis Signals
Authors: Wang Ying , Mo Jin‐Yuan
Published: September 2010

Capillary electrophoresis (CE) is a powerful analytical tool in chemistry. Thus, it is valuable to solve the denoising of CE signals. A new denoising method called MWDA which employs Mexican Hat wavelet is presented. It is an efficient chemometrics technique and has been applied successfully in processing CE signals. Useful information can be extracted even from signals of S/N = 1. After denoising, the peak positions are unchanged and the relative errors of peak height are less than 3%.
Simple and Clean Synthesis: Tin‐mediated Allylation of Carbonyl Compounds in Water
Authors: Zhou Cun‐Liu , Zha Zheng‐Gen , Wang Zhi‐Yong , Wu Ji‐Hui , Zhang Jia‐Hai
Published: September 2010

Tin‐mediated allylation of aldehydes or ketones in distilled water gives rise to the corresponding homoallyl alcohols in high yield without assistance such as heat, supersonic and acidic media.
Reaction Mechanism Investigation Using Vibrational Mode Analysis for the Multichannel Reaction of CH3O + CO
Authors: Zhou Zheng‐Yu , Cheng Xue‐Li , Guo Li
Published: September 2010

On the basis of the computed results got by the Gaussian 94 package at B3LYP/6‐311 + +G * * level, the reaction mechanism of CH3O radical with CO has been investigated thoroughly via the vibrational model analysis. And the relationships among the reactants, eight transition states, four intermediates and various products involved this multichannel reaction are elucidated. The vibrational mode analysis shows that the reaction mechanism is reliable.
Bioelectrochemical Response and Kinetics of Choline Oxidase Entrapped in Polyaniline‐Polyacrylonitrile Composite Film
Authors: Xue Huai‐Guo , Shen Zhi‐Quan
Published: September 2010

A novel choline oxidase electrode was constructed by entrapping choline oxidase into polyaniline‐polyacrylonitrile composite film. The enzyme film was prepared by in situ electropolymerization of aniline into porous polyacrylonitrile‐coated platinum electrode in the presence of choline oxidase. The enzyme electrode exhibited sensitive and stable electrochemical response to choline. The kinetics analysis showed that the mass transport is partially rate‐limiting. The influences of pH, applied potential and temperature on the response of the enzyme electrode were also described.
Cross‐Coupling of Aryl Iodides with Malononitrile Catalyzed by Palladium N‐ Heterocyclic Carbene Complex System
Authors: Gao Cheng‐Wei , Tao Xiao‐Chun , Liu Tao‐Ping , Huang Ji‐Ling , Qian Yan‐Long
Published: September 2010

Eight N‐heterocyclic carbenes (NHC), generated in situ from their imidazolium salts, as ligands of palladium complexes were used for the catalytic coupling of iodobenzene with malononitrile anion. It was found that 1,3‐bis (2,4,6‐trimethylphenyl) ‐imidazolium chloride (IMesHCl)‐Pd2 (dba) 3 catalytic system has the highest activity to obtain phenyl malononitrile among the imidazolium salts. The substituted iodoarenes reacted with malononitrile anions by using the catalytic system to give cross‐coupling products in yields from 50% to 96%.
Action of the Selenomorpholine Compounds on the Bacterium Growth by Microcalorimetry
Authors: Li Xi , Liu Yi , Wu Jun , Qu Song‐Sheng
Published: September 2010

The action of β‐(N‐selenomorpholine) ethyl phenyl ketone hydrochloride and 4‐(N‐selenomorpholine)‐2‐butanone hydrochloride on Escherichia coli and Staphylococcus aureus was studied by microcalorimetry. Differences in their capacities to affect the metabolism of this bacterium were observed. The kinetics shows that the selenomorpholine compounds had action on the metabolism process of Escherichia coli and Staphylococcus aureus. The rate constant (k) of the studied bacterium in the presence of the drugs are concentration‐dependant. The growth rate constants decrease with an increase in the mass of the selenomorpholine compounds, but their relationship is different. As deduced from the rate constant (k) of the studied bacterium (in log phase) and the half inhibitory concentration (IC50), the experimental results reveal that the studied selenomorpholine compounds all have good antibiotic activity and better antibacterial activity on Staphylococcus aureus than on Escherichia coli.
Diterpenoids from Isodon sculponeatus
Authors: Jiang Bei , Mei Shuang‐Xi , Zhao Ai‐Hua , Sun Han‐Dong , Lu Yang , Zheng Qi‐Tai
Published: September 2010

Further investigation on the leaves of Isodon sculponeatus afforded two new ent‐kaurane diterpenoids, sculponeatins J and K. Their structures were elucidated on the basis of their spectral properties, as well as X‐ray crystallographic analysis. The cytotoxicities of these two new compounds against human tumor cells K562 and T24 were also tested, and sculponeatin J showed significant inhibitory effects with IC50 values less than 1.0 μg/mL.
Study of the Complexation Behavior of Calixarene with Transition Metal Cations by UV‐vis and Fluorescent Spectra
Authors: Yang Jun‐Lin , Yu Qi Zheng , An Li‐Na , Chen Chuan‐Feng , Lin Hong‐Zhen , Bai Feng‐Lian , Huang Zhi‐Tang
Published: September 2010

A new fluorescent compound based on calix [4] arene skeleton was synthesized. Its complexation ability with transition metal ions, such as Fe3+, Co2+, Ni2+, Cu2+, Zn2+ and Ag+, was investigated by UV‐vis and fluorescent spectra.
1,3‐Diphenyl‐5‐(9‐phenanthryl)‐2‐pyrazoline(DPPhP): An Excellent Hole‐Transport Material for Use in Organic Light‐Emitting Diodes
Authors: Ma Chang‐Qi , Zhang Lian‐Qi , Zhou Jia‐Hong , Wang Xue‐Song , Zhang Bao‐Wen , Cao Yi , Bugnon P. , Schaer M. , Nüesch F. , Zhang De‐Qiang , Qiu Yong
Published: September 2010

An excellent hole‐transport material, 1, 3‐diphenyil‐5‐(9‐phenanthryl)‐2‐pyrazoline (DPPhP) for OLEDs was studied. This compound not only offers high glass transition temperature (Tg = 96 °C), good film forming ability, and high HOMO energy level, but also displays excellent hole‐transport property. The electroluminescent device with a simple structure of ITO/DPPhP (60 nm)/AlQ (60 nm)/LiF (0.8 nm)/Al shows an external quantum efficiency as high as 1.6%.
[H2N(C2H4)2NH2]4 (H3O) [PMo2VMo6VIV4IVO40(VIVO)2] · H2O: A New Highly Reduced, Bicapped Pseudo‐Keggin Vanadylpolymolybdophosphate
Authors: Li Yang‐Guang , Wang En‐Bo , De‐Hu Ge‐Ji , Zhang Hong , Hu Chang‐Wen , Hu Ning‐Hai , Jia Heng‐Qing
Published: September 2010

A new vanadylpolymolybdophosphate, [H2N (C2H4)2 NH2]4 (H3O) [PMo2VMo6VIV4IVO40 (VIVO)2] · H2O, was hydrothermally synthesized and structurally characterized by elemental analyses, IR, UV‐vis, XPS, ESR spectra, and single crystal X‐ray diffraction analysis. The compound contains an unusual highly reduced pseudo‐Keggin type polyoxoanion with nine negative charges and exhibits an interesting phosphorus‐centered alternate layer arrangement of molybdenum and vanadium oxides.
Mapping the Binding Site of P53 on UBC9 by NMR Spectroscopy
Authors: Lin Dong‐Hai
Published: September 2010

Human UBC9 is a member of the E2 family of proteins. However, instead of conjugating to ubiquitin, it conjugates to a ubiquitin homologue SUMO‐1 (also known as UBL1, GMP1, SMTP3, PICT‐1 and sentrin). The SUMO‐1 conjugation pathway is very similar to that of ubiquitin with regard to the primary sequences of the ubiquitin activating enzymes (E1), the three‐dimensional structures of the ubiquitin conjugating enzymes (E2), and the chemistry of the overall conjugation pathway. The interaction of p53 and UBC9, the E2 of the SUMO‐1 pathway, has been studied by nuclear magnetic resonance spectroscopy. A peptide corresponding to the nuclear localization domain of p53 specifically interacts with UBC9 and this interaction is likely to be important for conjugation of p53 with SUMO‐1. The largest chemical shift changes on UBC9 occur at residues 94 and 129–135. This region is adjacent to the active site and has significant dynamic behavior on the μs—ms and ps—ns timescales. Correlation of chemical shift changes and mobility of these residues further suggest the importance of these residues in substrate recognition.
Influence of a Hydrophobic Environment on the Structure of Arginine‐Carboxylate Salt Bridge
Authors: Feng Yong , Liu Lei , Mu Ting‐Wei , Guo Qing‐Xiang
Published: September 2010

The exact structure of an arginine‐carboxylate salt bridge in different chemical environments remains a controversial problem. In the present work, the zwitterionic and neutral forms of arginine‐carboxylate salt bridge were studied by the B3LYP/6‐311G (d, p)//PM3 method. It turns out that the neutral forms are more stable than the zwitterionic counterparts in gas phase. However, when bound by α‐cyclodextrin, the zwitterionic forms become more stable than the corresponding neutral ones. It is suggested that the hydrophobic environment provided by the cydodextrin cavity leads to such behavior. Therefore, the salt bridge still could be in a zwitterionic form in the hydrophobic interior of the real proteins.
Effect of Chemical Treatment on TiO2 Particles by IMPS
Authors: Yin Feng , Lin Yuan , Lin Rui‐Feng , Li Xue‐Ping , Xiao Xu‐Rui
Published: September 2010

The photodegradation reaction rate of CHCl3, in TiO2 particulate suspension was improved significantly by HCl‐treatment. The effect of HCl‐treatment on the photocatalytic activity of TiO2 was studied in a PEC cell by using Intensity‐Modulated Photocurrent Spectroscopy (IMPS). The magnitude of photocurrent response and the characteristic frequencies of the upper and lower semicircles in the complex plane of IMPS response were analyzed, and the cathodic and anodic reaction processes of photogenerated holes and electrons were discussed. The increases in the cathodic and anodic photocurrent response and in the time constants of both cathodic and anodic reaction processes indicate that HCl‐treatment leads to the improvement of the photocatalytic activity of TiO2 and a change of the photocatalytic kinetic mechanism.
Prediction of Decomposition Temperature for Lanthanide Complexes Involving Cyclopentadienyl and Benzohydroxamic Acid Ligand by ANNs
Authors: Sun Yi‐Min , Ling Qing , Wan Yu‐Bao , Wang Xiu‐Ran , Yu Hai‐Yin
Published: September 2010

The decomposition temperatures of the lanthanide organic complexes (η5‐C5H5)2 Ln(C6H5CONHO) involving cyclopentadienyl and benzohydroxamic acid ligands were calculated and predicted by the model based on ANNs (artificial neural networks) method. The comparison was carried out between results from ANNs method and traditional regression method. It is proved that ANNs could be used more efficiently for the prediction of decomposition temperature of lanthanide organic complexes.
Standard Enthalpies of Formation for Solid Complexes of Chromium Chloride with L‐α ‐ Amino Acids
Authors: Yang Xu‐Wu , Chen San‐Ping , Gao Sheng‐Li , Shi Qj‐Zhen
Published: September 2010

The solid complexes of Cr(AA)2 Cl3 · nH2O of CrCl3, with L‐α‐amino acids (AA= Val, Leu, Thr, Met, Arg, Phe, Try and His) have been prepared in 95% EtOH medium, and characterized structurally by elemental analysis, chemical analysis, IR spectra and TG‐DTG. The constant‐volume combustion energies of the complexes have been determined by RBC‐II type rotating‐bomb calorimeter. The standard enthalpies of formation of the complexes have been calculated as well, which are (‐2543.16 ± 3.71) (Val), ( −2561.32 ± 4.06) (Leu), (‐2284.02 ± 2.95) (Thr), (‐1418.77 ± 4.60) (Met), (‐3218.91 ± 4.67) (Arg), (‐2643.90 ± 5.02) (Phe), (‐1707.18 ± 3.23) (Try) and (‐2838.05 ± 3.45) (His) kJ/mol, respectively.
Photophysical Properties and Photoinduced Electron Transfer between [60]Fullerene‐Containing Cyclic Sulphoxide [ C60‐C6H8SO] and Tetrathiafulvalene (TTF) by Laser Flash Photolysis
Authors: Zeng He‐Ping
Published: September 2010

Photoinduced electron transfer (PET) processes between C60‐C6H8SO and Tetrathiafulvalene (TTF) have been studied by nanosecond laser photolysis. Quantum yields (ϕet) and rate constants of electron transfer (ket) from TTF to excited triplet state of [60] fullerene‐containing cyclic sulphoxide in benzonitrile (BN) have been evaluated by observing the transient absorption bands in the NIR region. With the decay of excited triplet state of [60] fullerene‐containing cyclic sulphoxide, the rise of radical anion of [60] fullerene‐containing cyclic sulphoxide is observed.
Transient Absorption Spectral Characterization of Electron Transfer between Fullerenes (C60/C70) and N, N, N′, N′‐Tetra (p‐methylphenyl) −4, 4′‐diamino‐1, 1′‐diphenyl Sulphide (TPDAS)
Authors: Zeng He‐Ping
Published: September 2010

In search of new systems with a photoexcited redox pair which exhibits a strong and stable photoinduced absorption band to understand the photophyscial and photochemical properties of electron transfer between fullerenes ( C60/C70 ) and organic donor [N, N, N′, N′‐tetra (p‐methylphenyl) −4, 4′‐diamino‐1, 1′‐diphenyl sulphide (TPDAS) ], we studied characteristic absorption spectra in the near‐IR region obtained from 532 nm nanosecond laser flash photolysis of a mixture of the fullerenes (C60/C70) and TPDAS in polar solvents. When fullerenes (C60/C70) were photoexcited, the rise of the radical anion of fullerenes (C60/C70) with the rapid decay of their excited triplet states were observed in benzonitrite. It can be deduced that the electron transfer reaction does take place from TPDAS to excited triplet state of fullerenes (C60/C70). The rate constants (ket) and quantum yields (ϕet) of this process have been also evaluated.
Investigation of Electrochemical Charging Behaviors of “Naked” Gold Nanoparticles Ensembles in Aqueous Media
Authors: Cheng Wen‐Long , Han Xiao‐Jun , Peng Zhang‐Quan , Dogn Shao‐Jun , Wang Er‐Kang
Published: September 2010

Gold nanoparticles were immobilized onto the electrode surface by simple self‐assembly technique. Interestingly, the ensembles of these nanoparticles exhibit quantized charging behaviors in aqueous solution. Possible mechanism for such behaviors was proposed.
Flow‐injection Chemiluminescence Sensor for the Determination of Gallic Acid by Immobilizing Luminol and Periodate on Anion‐exchange Resin
Authors: Zhang Si‐Chun , Zhou Guo‐Jun , Ju Huang‐Xian
Published: September 2010

A novel chemieluminescence (CL) sensor for the determination of gallic acid combined with flow injection analysis was developed by electrostatically immobilizing luminol and periodate on anion‐exchange resins respectively. Gallic acid was sensed by its enhancing effect on the weak CL reaction between luminol and periodate, which were eluted from the ion exchange column. The possible reaction mechanism of the CL system was suggested and discussed. The response of the sensor to gallic acid concentration was linear over the range of 8.0 × 10−9‐1.0 × 10−6 mol/L with a detection limit of 6.5 × 10−9 mol/L (3°). The relative standard deviation (RSD) for 7 repetitive determinations of gallic add (1.0 × 10−7 mol/L) was 1.8%. The sensor could be used for over 400 times determination with a good reproducibility.
Synthesis, Crystal Structure and Photophysical Properties of a Novel Molecule Containing a Triarylamine and an Oxadiazole Units
Authors: Yu Hai‐Tao , Zhang Wan‐Xuan , Bai Dong‐Ren , Meng Ji‐Ben
Published: September 2010

2‐{3‐[2‐(4‐N, N‐Di‐p‐tolylaminophenyl)ethenyl]phenyl}‐5‐(4‐bromophenyl)‐1,3,4‐oxadiazole (1) containing triarylamine and 2,5‐diaryi‐1,3,4‐oxadiazole units was prepared by Homer Witting reactions. The structure of the compound was confirmed by 1H NMR, IR, MS and elemental analyses. The crystal structure of 1 was determined by X‐ray diffraction analysis. UV absorption spectra and photoluminescent spectra were measured.
A Practical Synthesis of 1‐Oxo‐1,2,3,4‐tetrahydroisoquinoline‐3‐carboxylic Acid Esters
Authors: Tang Lei , Yang Yu‐She , Ji Ru‐Yun
Published: September 2010

A practical synthetic method for methyl 1‐oxo‐1, 2,3,4‐tetrahydroisoquinoline‐3‐carboxylate was developed by means of triphosgene. Several analogues were prepared by this new method.
Synthesis of a Tweezer‐like Bis(phenylthiapropoxy)calix[4]‐arene as a Cation/π Enhanced Sensor for Ion‐Selective Electrodes
Authors: Sun Hao , Zeng Xian‐Shun , Liu Jian‐Quan , Leng Xue‐Bing , Qi‐Fa Chen , Xu Feng‐Bo , Li Qing‐Shan , He Xi‐Wen , Zhang Wen‐Qin , Zhang Zheng‐Zhi
Published: September 2010

Two novel 25,27‐dihydroxy‐26,28‐bis(3‐phenyilhiapropoxy)‐calix[4]arene (3) and 25,27‐dihydroxy‐26,28‐bis(3‐phenylthiapropoxy)‐5,11, 17, 23‐tetra‐tert‐butylcalix[4]arene (4) were synthesized for the evaluation of their ion‐selectivity in ion‐selective electrodes (ISEs). ISEs based on 3 and 4 as neutral ionophores were prepared, and their selectivity coefficients for Ag+ (lg Apotag,M) were investigated against other alkali metal, alkaline‐earth metal, aluminum, thallium (I), lead and some transition metal ions using the separate solution method (SSM). These ISEs showed excellent Ag+ selectivity over most of the interfering cations examined, except for Hg2+ and Fe2+ having relative smaller interference (Ig Kpotag,M≤ − 2.1).
One‐dimensional Infinite Chain Organotin Compounds: Synthesis and Structural Characterization of Triphenyltin Thiazole‐2‐carboxylate and Triphenyltin 3‐Pyridinylcarboxylate
Authors: Yin Han‐Dong , Wang Chuan‐Hua , Ma Chun‐Lin , Wang Yong
Published: September 2010

Triphenyltin thiazole‐2‐carboxylate (1) and triphenyltin 3‐pyridinylcarboxylate (2) were synthesized by the reaction of sodium thiazole‐2‐carboxylate or sodium 3‐pyridinylcarboxylate with the triphenyltin chloride and their crystal structures were determined by single crystal X‐ray diffraction analysis. In the structure of 1, the tin atom is five‐coordinated in a distorted trigonal bipyramidal structure. Due to the presence of a close intermolecular Sn…S interaction distance of 0.3666 nm, the structure can be described as a weakly‐bridged one‐dimensional chain compound. In the structure of 2, the tin atom is five‐coordinated with bridging 3‐pyridinylcarboxylate ligands N atom and resulting structure is one‐dimensional chain compound.
Structure of Hexakis (imidazole) nickel (II) Nitrate Water Solvate: [Ni(Im)6](NO3)2‐4H2O
Authors: Jian Fang‐Fang , Zhao Pu‐Su , Xiao Hai‐Lian , Zhang Shu‐Sheng
Published: September 2010

Crystal structure of the title compound, [Ni(Im)6] (NO3)2·4H2O (Im = imidazole), was determined by X‐ray crystallographic analysis. The crystal structure consists of discrete Ni(Im)26+ cation, NO−3 anion and four uncoordinated water molecules. It crystallizes in the hexagonal system, space group P63, with lattice parameters a = b = 0.9003(2) nm, c = 2.1034(4) nm, and Z = 2. The Ni(II) ion is centro‐ symmetric octahedron geometry with the NiN6 core. Six imidazole molecules are coordinated to each nickel (II) atom through its tertiary nitrogen atom. The short and long bond distances of Ni‐N are 0.2059(6) and 0.2204(7) nm, respectively. In the solid state, [Ni(Im)6]2+, H2O moieties and nitrate anions form the three dimensional hydrogen bonds network which stabitizes the crystal structure.
The First Total Synthesis of 4,4′‐Biisofraxidin
Authors: Lei Jiang‐Guang , Lin Guo‐Qiang
Published: September 2010

The 4,4′‐biisofraxdin, isolated from balsamina L. was synthesized for the first time in the total yield of 7% by 11 steps, in which the key step was the cyclization and Ni(0)‐catalyzed coupling reaction.
Synthesis of a Novel Perfluorinated Vinyl Ether Containing Sulfonimide and Phosphonic Acid Functionalities
Authors: Zhu Shi‐Zheng , Jin Gui‐Fang , Desmarteau D. D.
Published: September 2010

The novel perfluorinated vinyl ether containing sulfonimide and phosphonic acid functionalities, CF2 = CFOCF2CF(CF3)‐OCF2CF2SO2NHSO2(CF2)2P(O)(OH)2, has been synthesized by multiple reaction steps. It is a very strong bi‐functional acid and exhibits a high degree of stability in aqueous solution at an elevated temperature. These properties make it an attractive monomer for the preparation of the co‐polymer with TFE to obtain the high quality ionomer membrane and proton conductor.
Preparation of 1,3‐Disubstituted‐5‐ cyano‐4,5‐dihydropyrazoles via 1,3‐Dipolar Cycloaddition of Nitrile Imine with Acrylonitrile
Authors: Song Li‐Ping , Zhu Shi‐Zheng , Huang Ji‐Ling
Published: September 2010

Oxidation of aldehyde 4‐chloro‐2, 3,5, 6‐tetrafluorophenylhydrazones (1) with [bis(acetoxy)iodo] benzene leads to the formation of nitrile imines (2) which can react in situ with acrylonitrile to produce l‐(4‐chloro‐2,3,5,6‐tetrafluorophenyl)‐3‐substituted‐5‐cyano‐4, 5‐dihydropyrazoles (3) in moderate to good yields. The structures of new compounds were fully confirmed by their spectral data and elemental analyses. A plausible reaction mechanism for the generation of nitrile imine is proposed.
A New Type of Deaggregators, the Bolaamphiphilic DeAgrs. Observations of the Dependence of Deaggregating Ability on Aggregator Concentration and Solvent Aggregating Power
Authors: Zhou Qi‐Zhong , Shi Ji‐Liang , Jiang Xi‐Kui , Li Zhan‐Tiiig
Published: September 2010

Four new amphiphilic molecules, i.e., the bolaamphiphiles n‐trimethylamino n‐hexadecanoate (deAgr 16), n‐dodecanoate (deAgr 12), n‐undecanoate (deAgr 11), and n‐octanoate (deAgr 8) were synthesized. Their ability as deaggregators to break up the aggregating systems of hexadecyl β‐naphthoate (A16) and dodecyl β‐naphthoate (A12) in dioxanewater binary solvent systems was investigated in a number of solvent systems and at different A16 and A12 concentrations. The results reveal that this new type of bolaamphiphilic molecules appears to be one of the most efficient deaggregators reported, which, at very low concentrations, can effectively break up the aggregating systems of highly concentrated A16 and A12. It is also found that bolaamphiphfles with longer aliphatic chains possess greater deaggregating ability. However, when the overall concentrations of A16 and A12 are very low but still above their critical aggregating concentration, these bolaamphiphilic molecules lose their deaggregating power and tend to coaggregate with the aggregated A16 or A12 molecules. The quite efficient deaggregating ability of the long‐chain bolaamphiphfles (deAgr 16 and deAgr 12), as compared to the short‐chain deAgr 8, has been ascribed to their dynamic switch‐on/switch‐off behavior involving coiled‐up and uncoiled conformations of their long aliphatic chains.
Studies on Synthesis and Antitumor Activity of Phosphorylated Achyranthes bidentata Polysaccharide (P‐AbPS)
Authors: Chen Xiao‐Ming , Zhang Jian , Han Geng‐Yuan
Published: September 2010

The synthesis of phosphorylated Achyranthes bidentata polysaccharide (P‐AbPS) was reported based on different strategies. The P‐AbPS with high degree of substitution (D.S. > 0.5) was obtained when phosphorus oxychloride (POCl3) was used as a phosphorylating agent and trimethyl phosphate‐pyridine or dimethyl formamide was used as solvent. The influences of different solvents and reaction conditions were discussed. The pharmacology assay shows that P‐AbPS possesses antitumor activity against sarcoma 180 and Lewis lung cancer in mice.
Synthesis of a New Polymer‐supported Reagent—Poly {[4‐hydroxy (tosyloxy) iodo] styrene} and Its Application to the Synthesis of 2‐Amino‐4‐arylthiazoles
Authors: Huang Xian , Zhu Qing , Zhang Ji‐Zhen
Published: September 2010

A new polymer‐supported reagent—poly {[4‐hydroxy (tosyloxy)iodo]styrene has good reactivity in the formation of 2‐amino‐4‐arylthiazoles, and the procedure of regeneration and cycle are also described.
Formal Synthesis of (+)‐Altholactone by Stereoselective Epoxidation Using Magnesium Monoperoxyphthalate (MMPP)
Authors: Li Jia‐Yao , Wang Zhi‐Qin , Zhao Gang , Teng Shang‐Jun , Ding Yu
Published: September 2010

Synthesis of (+)‐altholactone has been achieved starting from L‐tartaric acid using (2S, 3R,4R,5R)‐2‐hydroxymethyl‐3,4‐bis(memoxymethoxy)‐5‐phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced by monoperoxyphthalate (MMPP) in high stereoselectivity (8.4:1).
New Chiral Substituted 8‐Quinolinyl‐oxazolines as Ligands for Copper(I)‐catalyzed Asymmetric Cyclopropanation
Authors: Li Xiao‐Guang , Wang Li‐Xin , Zhou Qi‐Lin
Published: September 2010

New chiral substituted 8‐quinolinyl‐oxazoline ligands have been synthesized and applied in the copper(I)‐catalyzed asymmetric cyclopropanation of styrene with alkyl diazoacetates. The steric effect in the ligands plays a significant role in the enantiocontrol in asymmetric cyclopropanation, while the electronic effect is less important.
Synthesis and Characterization of Surfactant‐encapsulated Polyoxoanions: [(CnH2n+1)2N(CH3)2]12[Mo36(NO)4Om(H2O)16] (n = 12, 18)
Authors: Bu Wei‐Feng , Zhang Jing , Wu Li‐Xin , Tang Au‐Chin
Published: September 2010

By employing electrostatic interaction as driving force, an organic/inorganic composite with positively charged dimethyl dialkyl‐chain ammonium surfactants encapsulating negatively charged (NH4)12[Mo36(NO)4O108(H2O)16]. 33H2O polyoxoanion was prepared. The structure of the novel organic/inorganic hybrid particle with hydrophilic core and hydrophobic shell in a defined stoichiometric ratio was confirmed by element analysis, 1H NMR and FT‐IR spectra. The property of the polyoxoanion was changed due to the encapsulation and it can be dissolved in organic solvent such as chloroform, benzene and toluene, but not dissolved in water.
Tetra‐substituted Amino Aluminum Phthalocyanine as a New Red‐region Fluorescent Substrate for Horseradish Peroxidase Based Enzyme‐linked Immunosorbent Assay
Authors: Yang Huang‐Haoa , Li Dong‐Hui , Chen Xiao‐Lan , Qu Hui‐Ying , Ding Ma‐Tai , Xu Jin‐Gou
Published: September 2010

The use of tetra‐substituted ammo aluminum phthalocyanine (TAAIPc) as a new red‐region fluorescent substrate for horseradish peroxidase (HRP)‐based enzyme‐linked immunosorbent assay was investigated. TAAIPc displayed an excitation maximum at 610 nm and emission maximum at 678 nm in a strong acidic medium. In the presence of HRP, trace amounts of H2O2 could rapidly and significantly react with TAAIPc, thus quenching the fluorescence of TAAIPc. The Michaelis‐Menten parameters Km and Vmax were measured to be 2.82 × 10−6 mol/L−1 and 6.0 × 10−9 mol·L−1, respectively. In this paper, TAAIPc was used in an HRP‐based enzyme‐linked immunosorbent assay (ELISA) of α‐fetoprotein (AFP) in human serum with satisfactory results. AFP could be determined in the concentration range of 0.5–200 ng/mL with a detection limit of 0.2 ng/mL, which was close to that of radioimmunoassay. The advantage of proposed method was strongly minimizing the interference resulting from background fluorescence or scattering light and had a high analytical sensitivity.
Application of the Ion Pair of 2‐(5‐Bromo‐2‐pyridylazo)‐5‐diethylaminophenol and Ammonium Tetraphenylborate for Pre‐concentration of Trace Vanadium and Determination by Third Derivative Spectrophotometry
Authors: Taher Mohammad Ali
Published: September 2010

Vanadium is quantitatively retained on 2‐(5‐bromo‐2‐pyridylazo)‐5‐diethylaminophenol (5‐Br‐PADAP)‐ammonium tetraphenylborate with microcrystalline naphthalene or by a column method in the pH range of 2.1–4.5 from a large volume of aqueous solutions of various samples. After filtration, the solid mass consisting of the vanadium complex and naphthalene was dissolved with 5 mL of dimethylformamide and the metal was determined by the third derivative spectrophotometry. Vanadium complex can alternatively be quantitatively adsorbed on ammonium tetraphenylborate‐naphthalene adsorbent packed in a column and determined similarly. About 0.05 μg of vanadium can be concentrated in a column from 250 mL of aqueous sample, where its concentration is as low as 0.2 ng/mL. The interference of a large number of anions and cations has been studied and the optimized conditions developed were utilized for the determination of trace amount of vanadium in various samples.
Synthesis and Crystal Structure of Two‐dimensional Network Supramolecular Complex [Cu(dafo)2 (H2O)2] (ClO4)2
Authors: Gu Ai‐Ping , Zhang Rong‐Lan , Zhang Gai , Zhao Jian‐She , He Shui‐Yang , Dou Jian‐Min , Wang Da‐Qi
Published: September 2010

In an attempt to synthesize supra‐molecular complex of copper (II) with mixed ligands in a solution reaction of Cu(ClO4)2· 6H2O with 4,5‐diazafluorene‐9‐one (dafo) and o‐phthalic add, the bright blue column‐like crystal [Cu(dafo)2(H2O)2]‐(ClO4)2 was obtained. Its structure was determined by single‐crystal X‐ray diffraction study. The crystal belongs to monoclinic system, space group P2(1)/n with cell dimensions: a = 0.7547(3) nm, b = 1.2021(5) nm, c = 1.3190(5) nm, α = 90.000(5)°, β = 90.000(5)°, γ = 90.000(5)°, V = 1.2600(9) nm3, Z = 2, F(000)=670, Mr = 662.83, Dc = 1.747 g/cm3, μ (Mo Kα) = 1.154 mm−1, R1, = 0.0455, wR2 = 0.1041. The analysis of the crystal structure indicates that the complex has a two‐dimensional network structure which is formed by hydrogen bonds.
One‐pot Synthesis of Isoxazolines Using Soluble Polymer‐supported Acrylate
Authors: Yong‐Jia Shang , Yan‐Guang Wang
Published: September 2010

An efficient liquid‐phase synthesis of isoxazolines through a 1,3‐dipolar cycloaddition is described. Soluble polymer‐supported acrylate reacted with nitrile oxides generated in‐situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.
3D‐QSAR Study on Diindolylmethane and Its Analogues with Comparative Molecular Field Analysis (CoMFA)
Authors: Hayat Benabadji Saldina , Ren Wen , Hai‐Feng Chen , Shen‐Gang Yuan
Published: September 2010

Comparative molecular field analysis (CoMFA), a three dimensional quantitative structure‐activity relationship (3D‐QSAR) method was applied to a series of diindolylmethane (DIM) analogs to study the relationship between their structure and their induction of CYP 1A1‐associated ethoxyresorufin‐O‐deethylase (EROD) activity. A DISCO model of pharmacophore was derived to guide the superposition of the compounds. The coefficient of cross‐validation (q2) and non cross‐validation (r2) for the model established by the study are 0.827 and 0.988 respectively, the value of variance ratio (F) is 103.53 and standard error estimate (SEE) is 0.044. These values indicate that the CoMFA model derived is significant and might have a good prediction for the catalytic activity of DIM compounds. As a consequence, the predicted activity values of new designed compounds were all higher than that of the reported value.
The Structures and Stability of HNOS Isomers
Authors: Yu‐Juan Chi , Hai‐Tao Yu , Hong‐Gang Fu , Bai‐Fu Xin , Ze‐Sheng Li , Jia‐Zhong Sun
Published: September 2010

Potential energy surface of HNOS system is investigated by means of MP2 method with 6–311 ++ G(d, p) basis set. The energy for each minimum and saddle point on the potential energy surface is corrected at the QCISD(T)/6–311 ++ G(3df, 2p) level of theory with zero‐point vibrational energy included. As a result, eighteen isomers are theoretically predicted and cis‐HNSO is found to be global minimum on the potential energy surface. Wherein, fourteen isomers are considered as kinetically stable species, and should be experimentally observed. Comparisons are made for HNOS system with its analogues, HNO2 and HNS2. The nature of bonding and isomers'stability of HNOS system are similar to HNS2. The obvious similarities and discrepancies among HNOS, HNO2 and HNS2 are attributed to the hypervalent capacity of sulfur, oxygen and nitrogen atoms.
A Novel Cu(II) Complex with 2,2′‐Bipyridyl and L‐Methioninate—Synthesis, Characterization, Molecular Structure and Stability
Authors: Xue‐Yi Le , Yin‐Lian Fu , Ming‐Liang Tong , Iiang‐Nian Ji
Published: September 2010

The ternary Cu(II) complex with 2,2′‐bipyridyl (bipy) and L‐methioninate (L‐Met) has been synthesized and characterized by elemental analysis, molar conductivity, UV‐Vis spectra, IR spectra and pH‐potentiometric titration methods. The structure of the complex [Cu(L‐Met) (bipy) (H2O)]ClO4 · 3/8H2O was characterized by the X‐ray diffraction analysis. It crystallizes in the triclinic system, space group P1 with four molecules in a unit cell of dimensions, a = 0.7656(2) nm, b = 1.3142(3) nm, c = 2.0596(4) nm, α = 97.70(3)°, β = 97.96(3)°, γ = 94.33(3)°, V= 2.0244(8) nm3, R1, = 0.0441 and wR2 = 0.0678. The crystal contains four crystllographically independent [Cu(L‐Met) (bipy) (H2O)]+ complexes (Cu1—Cu4), having a distorted square‐pyramidal geometry with the same coordinated atoms around each copper center. The base plane is occupied by two nitrogen atoms of one bipy, the amino nitrogen atom and one carboxylate oxygen atom from each independent L‐Met moiety, and one water oxygen at an axial position. Cu1 and Cu3 are essentially enantiomers of Cu2 and Cu4. The four molecules are packed with each other by intermolecular hydrogen‐bonding and aromatic‐ring stacking interactions.
Resonance Rayleigh Scattering Spectra of Thorium (IV)‐bisazo Dye of Chromotropic Acid‐protein Systems and Their Analytical Applications
Authors: Fan U , Shao‐Pu Liu , Da‐Cheng Yang , Hong‐Qun Luo
Published: September 2010

In acidic medium, thorium (IV) can react with a bisazo dye of chromotropic adds such as arsenazo HI (AA in), arsenazo M (AA M), chlorophosphonazo III (CPA III) and chlorosulphonphenol S (CSP S) to form an anionic chelate which further interacts with some proteins to produce a complex. This results in a significant enhancement of intensity of the resonance Rayleigh scattering (RRS) and the appearance of a new RRS spectrum. There are a few obvious RRS peaks in the range of 400–470 nm and the most intensive peak of them is located at 470 nm. The intensity of RRS is directly proportional to the concentration of protein in the range of 0—l.öμg‐mL−1 for Th(IV)‐CPA III system, 0–2.8 μg‐mL−1 for Th(IV)‐AA M system, 0–2.0 μg·mL−1 for Th(IV)‐AA III system and 0–0.28 μg·mL−1 for Th(IV)‐CSP S system, respectively. The detection limits for BSA (3s̀) are 10.7 ng·mL−1 for Th (IV)‐CPA III, 6.3 ng·mL−1 for Th(IV)‐CSP S, 13.6 ng·mL−1 for Th(IV)‐AA III and 22.1 ng·mL−1 for Th(IV)‐AA M, respectively. This new RRS method has high sensitivity and fairly good selectivity and can be applied to the direct determination of proteins in human serum with satisfactory results.