bluuebunny/crossref_metadata_2025 huggingface dataset:
Rapid monoisotopic cisplatin based barcoding for multiplexed mass cytometry
Authors: McCarthy Ryan L. , Mak Duncan H. , Burks Jared K. , Barton Michelle C.
Published: June 2017

Mass cytometry presents an exceptional opportunity to interrogate the biology of highly heterogeneous cell populations, owing to the ability to collect highly parametric proteomic data at a single cell level. However, sample-to-sample variability, due to antibody staining and/or instrument sensitivity, can introduce substantial artifacts into the data, which can in turn lead to erroneous conclusions. This variability can be eliminated by sample barcoding which enables samples to be pooled, stained and run simultaneously. Existing mass cytometry barcoding approaches require time intensive labeling, reduce the number of biologically meaningful parameters and/or rely on expensive reagents. We present an approach utilizing monoisotopic cisplatin to perform cell barcoding that does not require cell permeabilization, can be completed in 10 minutes and can be utilized in combination with existing barcoding techniques to greatly increase the number of samples which can be multiplexed to improve throughput and consistency.
Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation
Authors: Pace Simona , Rossi Antonietta , Krauth Verena , Dehm Friederike , Troisi Fabiana , Bilancia Rossella , Weinigel Christina , Rummler Silke , Werz Oliver , Sautebin Lidia
Published: June 2017

The severity and course of inflammatory processes differ between women and men, but the biochemical mechanisms underlying these sex differences are elusive. Prostaglandins (PG) and leukotrienes (LT) are lipid mediators linked to inflammation. We demonstrated superior LT biosynthesis in human neutrophils and monocytes, and in mouse macrophages from females, and we confirmed these sex differencesin vivowhere female mice produced more LTs during zymosan-induced peritonitis versus males. Here, we report sex differences in PG production in neutrophils during acute inflammation. In the late phase (4–8 hrs) of mouse zymosan-induced peritonitis and rat carrageenan-induced pleurisy, PG levels in males were higher versus females, seemingly due to higher PG production in infiltrated neutrophils. Accordingly, human neutrophils from males produced more PGE2than cells from females. Increased PG biosynthesis in males was accompanied by elevated cyclooxygenase (COX)-2 expression connected to increased nuclear factor-kappa B activation, and was abolished when LT synthesis was pharmacologically blocked, suggesting that elevated PG production in males might be caused by increased COX-2 expression and by shunting phenomena due to suppressed LT formation. Conclusively, our data reveal that the biosynthesis of pro-inflammatory PGs and LTs is conversely regulated by sex with consequences for the inflammatory response.
Exploration of binding and inhibition mechanism of a small molecule inhibitor of influenza virus H1N1 hemagglutinin by molecular dynamics simulation
Authors: Guan Shanshan , Wang Tianao , Kuai Ziyu , Qian Mengdan , Tian Xiaopian , Zhang Xiuqi , Yu Yongjiao , Wang Song , Zhang Hao , Li Hao , Kong Wei , Shan Yaming
Published: June 2017

Influenza viruses are a major public health threat worldwide. The influenza hemagglutinin (HA) plays an essential role in the virus life cycle. Due to the high conservation of the HA stem region, it has become an especially attractive target for inhibitors for therapeutics. In this study, molecular simulation was applied to study the mechanism of a small molecule inhibitor (MBX2329) of influenza HA. Behaviors of the small molecule under neutral and acidic conditions were investigated, and an interesting dynamic binding mechanism was found. The results suggested that the binding of the inhibitor with HA under neutral conditions facilitates only its intake, while it interacts with HA under acidic conditions using a different mechanism at a new binding site. After a series of experiments, we believe that binding of the inhibitor can prevent the release of HA1 from HA2, further maintaining the rigidity of the HA2 loop and stabilizing the distance between the long helix and short helices. The investigated residues in the new binding site show high conservation, implying that the new binding pocket has the potential to be an effective drug target. The results of this study will provide a theoretical basis for the mechanism of new influenza virus inhibitors.
Comprehensive analysis of passive generation of parabolic similaritons in tapered hydrogenated amorphous silicon photonic wires
Authors: Mei Chao , Li Feng , Yuan Jinhui , Kang Zhe , Zhang Xianting , Yan Binbin , Sang Xinzhu , Wu Qiang , Zhou Xian , Zhong Kangping , Wang Liang , Wang Kuiru , Yu Chongxiu , Wai P. K. A.
Published: June 2017

Parabolic pulses have important applications in both basic and applied sciences, such as high power optical amplification, optical communications, all-optical signal processing, etc. The generation of parabolic similaritons in tapered hydrogenated amorphous silicon photonic wires at telecom (λ ~ 1550 nm) and mid-IR (λ ≥ 2100 nm) wavelengths is demonstrated and analyzed. The self-similar theory of parabolic pulse generation in passive waveguides with increasing nonlinearity is presented. A generalized nonlinear Schrödinger equation is used to describe the coupled dynamics of optical field in the tapered hydrogenated amorphous silicon photonic wires with either decreasing dispersion or increasing nonlinearity. The impacts of length dependent higher-order effects, linear and nonlinear losses including two-photon absorption, and photon-generated free carriers, on the pulse evolutions are characterized. Numerical simulations show that initial Gaussian pulses will evolve into the parabolic pulses in the waveguide taper designed.
Initial pseudo-steady state & asymptotic KPZ universality in semiconductor on polymer deposition
Authors: Almeida Renan A. L. , Ferreira Sukarno O. , Ferraz Isnard , Oliveira Tiago J.
Published: June 2017

The Kardar-Parisi-Zhang (KPZ) class is a paradigmatic example of universality in nonequilibrium phenomena, but clear experimental evidences of asymptotic 2D-KPZ statistics are still very rare, and far less understanding stems from its short-time behavior. We tackle such issues by analyzing surface fluctuations of CdTe films deposited on polymeric substrates, based on a huge spatio-temporal surface sampling acquired through atomic force microscopy. A pseudo-steady state (where average surface roughness and spatial correlations stay constant in time) is observed at initial times, persisting up to deposition of ~104 monolayers. This state results from a fine balance between roughening and smoothening, as supported by a phenomenological growth model. KPZ statistics arises at long times, thoroughly verified by universal exponents, spatial covariance and several distributions. Recent theoretical generalizations of the Family-Vicsek scaling and the emergence of log-normal distributions during interface growth are experimentally confirmed. These results confirm that high vacuum vapor deposition of CdTe constitutes a genuine 2D-KPZ system, and expand our knowledge about possible substrate-induced short-time behaviors.
Two-dimensional fluorescence spectroscopy of uranium isotopes in femtosecond laser ablation plumes
Authors: Phillips Mark C. , Brumfield Brian E. , LaHaye Nicole , Harilal Sivanandan S. , Hartig Kyle C. , Jovanovic Igor
Published: June 2017

We demonstrate measurement of uranium isotopes in femtosecond laser ablation plumes using two-dimensional fluorescence spectroscopy (2DFS). The high-resolution, tunable CW-laser spectroscopy technique clearly distinguishes atomic absorption from 235U and 238U in natural and highly enriched uranium metal samples. We present analysis of spectral resolution and analytical performance of 2DFS as a function of ambient pressure. Simultaneous measurement using time-resolved absorption spectroscopy provides information on temporal dynamics of the laser ablation plume and saturation behavior of fluorescence signals. The rapid, non-contact measurement is promising for in-field, standoff measurements of uranium enrichment for nuclear safety and security.
Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
Authors: Srdic-Rajic Tatjana , Santibañez Juan F. , Kanjer Ksenija , Tisma-Miletic Nevena , Cavic Milena , Galun Daniel , Jevric Marko , Kardum Nevena , Konic-Ristic Aleksandra , Zoranovic Tamara
Published: June 2017

Chemotherapy in patients with inoperable or advanced breast cancer inevitably results in low-dose exposure of tumor-cell subset and senescence. Metabolically active senescent cells secrete multiple tumor promoting factors making their elimination a therapeutic priority. Viscum album is one of the most widely used alternative anti-cancer medicines facilitating chemotherapy tolerance of breast cancer patients. The aim of this study was to model and investigate how Viscum album extracts execute additive anti-tumor activity with low-dose Dox using ER + MCF7 breast cancer cells. We report that cotreatment of MCF7 with Viscum album and Dox abrogates G2/M cycle arrest replacing senescence with intrinsic apoptotic program. Mechanistically, this switch was associated with down-regulation of p21, p53/p73 as well as Erk1/2 and p38 activation. Our findings, therefore, identify a novel mechanistic axis of additive antitumor activity of Viscum album and low dose-Dox. In conclusion, ER + breast cancer patients may benefit from addition of Viscum album to low-dose Dox chemotherapy due to suppression of cancer cell senescence and induction of apoptosis.
Metallicity in a Holstein-Hubbard Chain at Half Filling with Gaussian Anharmonicity
Authors: Lavanya Ch. Uma , Sankar I. V. , Chatterjee Ashok
Published: June 2017

The Holstein-Hubbard model with Gaussian phonon anharmonicity is studied in one-dimension at half filling using a variational method based on a series of canonical transformations. A fairly accurate phonon state is chosen to average the transformed Holstein-Hubbard Hamiltonian to obtain an effective Hubbard model which is then solved using the exact Bethe - ansatz following Lieb and Wu to obtain the ground state energy, the average lattice displacement and the renormalized parameters. The Mott-Hubbard criterion, local spin moment and the von Neumann entropy (which is a measure of quantum entanglement) are calculated to determine the ground state phase diagram which shows that the width of the metallic phase flanked by the SDW and CDW phases increases with increasing anharmonicity at low and moderate values of anharmonicity but eventually saturates when the anharmonicity becomes substantially large.
Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers
Authors: Sartaj R. , Zhang C. , Wan P. , Pasha Z. , Guaiquil V. , Liu A. , Liu J. , Luo Y. , Fuchs E. , Rosenblatt M. I.
Published: June 2017

In order to identify reliable markers of corneal epithelial stem cells, we employed an inducible transgenic “pulse-chase” murine model (K5Tta × TRE-H2BGFP) to localize, purify, and characterize slow cycling cells in the cornea. The retention of GFP labeling in slowly dividing cells allowed for localization of these cells to the corneal limbus and their subsequent purification by FACS. Transcriptome analysis from slow cycling cells identified differentially expressed genes when comparing to GFP- faster-dividing cells. RNA-Seq data from corneal epithelium were compared to epidermal hair follicle stem cell RNA-Seq to identify genes representing common putative stem cell markers or determinants, which included Sox9, Fzd7, Actn1, Anxa3 and Krt17. Overlapping retention of GFP and immunohistochemical expression of Krt15, ΔNp63, Sox9, Actn1, Fzd7 and Krt17 were observed in our transgenic model. Our analysis presents an array of novel genes as putative corneal stem cell markers.
Hyperuricemia and overexcretion of uric acid increase the risk of simple renal cysts in type 2 diabetes
Authors: Han Ying , Zhang Mingliang , Lu Junxi , Zhang Lei , Han Junfeng , Zhao Fangya , Chen Haibing , Bao Yuqian , Jia Weiping
Published: June 2017

Previous studies have discussed the relationship between simple renal cysts (SRC) and serum uric acid level in healthy individuals. We performed a cross-sectional study to evaluate the association between serum uric acid level and fractional excretion of uric acid (FEUA) and simple renal cysts in males and postmenopausal females with type 2 diabetes. The overall prevalence of SRC was 18.1% in our population. SRC prevalence was significantly higher in hyperuricemic than normouricemic subjects (27.3% vs. 16.8%, P < 0.001). Subjects who overexcreted uric acid had a higher prevalence of SRC than underexcretors (total population: 21.6% vs. 16.3%; normouricemic subjects: 19.8% vs. 13.7%; hyperuricemic subjects: 50.0% vs. 22.7%, all P-values < 0.05). Hyperuricemia (odds ratio [OR] 1.824, 95% confidence interval [CI] 1.332–2.498, P < 0.001); FEUA (OR 1.046, 95% CI 1.002–1.091, P < 0.05); male gender (OR 1.922, 95% CI 1.489–2.480, P < 0.001); age (OR 1.049, 95% CI 1.035–1.064, P < 0.001); and albuminuria (OR 1.492, 95% CI 1.176–1.892, P < 0.01) were independent risk factors for SRC development. These findings suggested that hyperuricemia and high level of FEUA were both independent risk factors for SRC development in males and postmenopausal females with type 2 diabetes. Half of overproduction hyperuricemic patients had SRC.
Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface
Authors: Perconti Giovanni , Maranto Cristina , Romancino Daniele P. , Rubino Patrizia , Feo Salvatore , Bongiovanni Antonella , Giallongo Agata
Published: June 2017

Cell surface expression of alpha-enolase, a glycolytic enzyme displaying moonlighting activities, has been shown to contribute to the motility and invasiveness of cancer cells through the protein non-enzymatic function of binding plasminogen and enhancing plasmin formation. Although a few recent records indicate the involvement of protein partners in the localization of alpha-enolase to the plasma membrane, the cellular mechanisms underlying surface exposure remain largely elusive. Searching for novel interactors and signalling pathways, we used low-metastatic breast cancer cells, a doxorubicin-resistant counterpart and a non-tumourigenic mammary epithelial cell line. Here, we demonstrate by a combination of experimental approaches that epidermal growth factor (EGF) exposure, like lipopolysaccharide (LPS) exposure, promotes the surface expression of alpha-enolase. We also establish Heat shock protein 70 (Hsp70), a multifunctional chaperone distributed in intracellular, plasma membrane and extracellular compartments, as a novel alpha-enolase interactor and demonstrate a functional involvement of Hsp70 in the surface localization of alpha-enolase. Our results contribute to shedding light on the control of surface expression of alpha-enolase in non-tumourigenic and cancer cells and suggest novel targets to counteract the metastatic potential of tumours.
The solution plasma process for heteroatom-carbon nanosheets: the role of precursors
Authors: Hyun Koangyong , Saito Nagahiro
Published: June 2017

The solution plasma process (SPP), known as non-equilibrium cold plasma at atmospheric pressure and room temperature, was used to investigate the synthesis of nitrogen-carbon nasnosheets (NCNs). To verify the effect of elementary composition and structure ofN-methyl-2-pyrrolidone (NMP), various precursors were used in the SPP to synthesize NCNs via the bottom-up synthesis method for the first time. The NCNs were analyzed by transmission electron microscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy. Among the various precursors, SPP of 2-pyrrolidone was demonstrated to facilitate the formation of highly ordered NCNs. On the other hand, the SPP with cyclopentanone, cyclohexanone and pyrrole did not lead to the formation of carbon nanosheets. The results of this study would uncover new parameter fields for the growth of heteroatom-carbon nanosheets using this synthesis system. In addition, the study is expected to contribute toward research in improving the large-area growth and quality of two-dimensional nanostructures, such as heteroatom-carbon nanosheets or graphene, for various applications in other synthesis methods.
Overcoming the biological aging of titanium using a wet storage method after ultraviolet treatment
Authors: Choi Sung-Hwan , Jeong Won-Seok , Cha Jung-Yul , Lee Jae-Hoon , Lee Kee-Joon , Yu Hyung-Seog , Choi Eun-Ha , Kim Kwang-Mahn , Hwang Chung-Ju
Published: June 2017

We evaluated whether the biological activity of the surface of titanium, when stored in an aqueous solution after ultraviolet (UV) treatment, is comparable to that of the surface immediately after UV treatment. We subjected Grade IV titanium discs with machined surfaces to UV radiation for 15 min and then tested them immediately and after storage for 28 days, with and without distilled H2O (dH2O). We evaluated the surface characteristics using surface profiling, contact angle analysis, X-ray photoelectron spectroscopy, and in terms of the surface zeta-potential. We determined the level of biological activity by analysing albumin adsorption, MC3T3-E1 and human mesenchymal cell adhesion and cytoskeleton development, as well as the production of intracellular reactive oxygen species between groups. The surface characteristics produced by the UV irradiation were maintained in dH2O for 28 days. We found that titanium stored in dH2O for 28 days after UV treatment exhibited enhanced protein adsorption, cell attachment, and cytoskeleton development. Titanium stored in dH2O for 28 days after UV irradiation exhibited a lower level of oxidative stress, comparable to that of the titanium immediately after UV treatment. UV treatment combined with wet storage can be used as a means of overcoming the biological aging of titanium.
Evidence for Chemical Vapor Induced 2H to 1T Phase Transition in MoX2 (X = Se, S) Transition Metal Dichalcogenide Films
Authors: Friedman Adam L. , Hanbicki Aubrey T. , Perkins F. Keith , Jernigan Glenn G. , Culbertson James C. , Campbell Paul M.
Published: June 2017

Electron-donors can impart charge to the surface of transition metal dichalcogenide (TMD) films while interacting with the film via a weak physisorption bond, making them ideal for vapor and gas sensors. We expose monolayer MoS2 and MoSe2 films to strong electron-donor chemical vapor analytes. After analyzing the resultant behavior and taking into consideration doping effects, we conclude that exposure to strong electron-donors could be a method of inducing the semiconductor-metal 2H-1T TMD phase transition. We find that the conductance response to strong electron donors in both monolayer MoS2 and MoSe2 FET devices ceases after moderate exposure, with final value of the conductance being on order of that expected for the 1T phase. Full device relaxation back to a semiconducting state is accomplished by annealing in vacuum at 400 °C. We also examine chemically exposed TMD films intermittently interrogated with Raman and photoluminescence spectroscopy. We observe the appearance of weak characteristic 1T phase Raman features for MoS2 and we observed a quenching of the photoluminescence of both TMD films that is recoverable with annealing. Considering all of our data together, the effects cannot be described by doping alone. Additionally, our results suggest a mechanism for a new type of passive chemical vapor sensor.
Experimental evidence of exciton capture by mid-gap defects in CVD grown monolayer MoSe2
Authors: Chen Ke , Ghosh Rudresh , Meng Xianghai , Roy Anupam , Kim Joon-Seok , He Feng , Mason Sarah C. , Xu Xiaochuan , Lin Jung-Fu , Akinwande Deji , Banerjee Sanjay K. , Wang Yaguo
Published: June 2017

In two dimensional (2D) transition metal dichalcogenides, defect-related processes can significantly affect carrier dynamics and transport properties. Using femtosecond degenerate pump-probe spectroscopy, exciton capture, and release by mid-gap defects have been observed in chemical vapor deposition (CVD) grown monolayer MoSe2. The observed defect state filling shows a clear saturation at high exciton densities, from which the defect density is estimated to be around 0.5 × 1012/cm2. The exciton capture time extracted from experimental data is around ~ 1 ps, while the average fast and slow release times are 52 and 700 ps, respectively. The process of defect trapping excitons is found to exist uniquely in CVD grown samples, regardless of substrate and sample thickness. X-ray photoelectron spectroscopy measurements on CVD and exfoliated samples suggest that the oxygen-associated impurities could be responsible for the exciton trapping. Our results bring new insights to understand the role of defects in capturing and releasing excitons in 2D materials, and demonstrate an approach to estimate the defect density nondestructively, both of which will facilitate the design and application of optoelectronics devices based on CVD grown 2D transition metal dichalcogenides.
A global dataset of crowdsourced land cover and land use reference data
Authors: Fritz Steffen , See Linda , Perger Christoph , McCallum Ian , Schill Christian , Schepaschenko Dmitry , Duerauer Martina , Karner Mathias , Dresel Christopher , Laso-Bayas Juan-Carlos , Lesiv Myroslava , Moorthy Inian , Salk Carl F. , Danylo Olha , Sturn Tobias , Albrecht Franziska , You Liangzhi , Kraxner Florian , Obersteiner Michael
Published: June 2017

Global land cover is an essential climate variable and a key biophysical driver for earth system models. While remote sensing technology, particularly satellites, have played a key role in providing land cover datasets, large discrepancies have been noted among the available products. Global land use is typically more difficult to map and in many cases cannot be remotely sensed. In-situ or ground-based data and high resolution imagery are thus an important requirement for producing accurate land cover and land use datasets and this is precisely what is lacking. Here we describe the global land cover and land use reference data derived from the Geo-Wiki crowdsourcing platform via four campaigns. These global datasets provide information on human impact, land cover disagreement, wilderness and land cover and land use. Hence, they are relevant for the scientific community that requires reference data for global satellite-derived products, as well as those interested in monitoring global terrestrial ecosystems in general.
Fluorine-18 labelled building blocks for PET tracer synthesis
Authors: van der Born Dion , Pees Anna , Poot Alex J. , Orru Romano V. A. , Windhorst Albert D. , Vugts Danielle J.
Published: June 2017

This review presents a comprehensive overview of the synthesis and application of fluorine-18 labelled building blocks since 2010.
Fluorescent miRNA analysis enhanced by mesopore effects of polydopamine nanoquenchers
Authors: Wang Zhenqiang , Zhang Jixi , Chen Feng , Cai Kaiyong
Published: June 2017

Mesoporous polydopamine nanoparticles can improve the differential surface affinity of single/double stranded oligonucleotides by pore effects toward sensitive miRNA detection.
Surface acoustic wave devices for chemical sensing and microfluidics: a review and perspective
Authors: Go David B. , Atashbar Massood Z. , Ramshani Zeinab , Chang Hsueh-Chia
Published: June 2017

Surface acoustic wave sensors and microfluidic platforms enable effective chemical detection and sample manipulation.
MRI-guided tumor chemo-photodynamic therapy with Gd/Pt bifunctionalized porphyrin
Authors: Wu Bo , Li Xiao-Qi , Huang Tong , Lu Shu-Ting , Wan Bing , Liao Ru-Fang , Li Yu-Shuang , Baidya Aju , Long Qing-Yun , Xu Hai-Bo
Published: June 2017

Gd/Pt bifunctionalized porphyrin derivative was synthesized for MRI-guided highly synergetic chemo-photodynamic therapy of cancer.
Development of air-stable hydrogen evolution catalysts
Authors: Mondal Biswajit , Dey Abhishek
Published: June 2017

Obtaining abundant pure hydrogen by reduction of water has an important implication in the development of clean and renewable energy.
Functionalised cyclodextrin-based metal–organic frameworks
Authors: Hartlieb K. J. , Peters A. W. , Wang T. C. , Deria P. , Farha O. K. , Hupp J. T. , Stoddart J. F.
Published: June 2017

A CD-MOF is prepared from amino-functionalized (blue moon) γ-CD, which permanently captures CO2as a carbamate (red moon).
Base-promoted, deborylative secondary alkylation of N-heteroaromatic N-oxides with internal gem-bis[(pinacolato)boryl]alkanes: a facile derivatization of 2,2′-bipyridyl analogues
Authors: Hwang Chiwon , Jo Woohyun , Cho Seung Hwan
Published: June 2017

A base-promoted, secondary alkylation of N-heteroaromatic N-oxides using internal gem-bis[(pinacolato)boryl]alkanes as alkylation reagents is achieved to form deoxygenated secondary alkylated N-heteroarenes.
Pd(0)-Catalyzed intramolecular arylative dearomatization of β-naphthols
Authors: Xu Ren-Qi , Yang Ping , You Shu-Li
Published: June 2017

An efficient Pd(0)-catalyzed intramolecular arylative dearomatization of β-naphthols was developed to afford a series of structurally diverse spirocarbocycles.
Spatial variation of lattice plane bending of 4H-SiC substrates
Authors: Cui Yingxin , Hu Xiaobo , Xie Xuejian , Wang Rongkun , Xu Xiangang
Published: June 2017

Basal plane bending of on- and off-axis 4H-SiC substrates was measured by high-resolution X-ray diffractometry (HRXRD).
Multiscale modeling of a rectifying bipolar nanopore: explicit-water versus implicit-water simulations
Authors: Ható Zoltán , Valiskó Mónika , Kristóf Tamás , Gillespie Dirk , Boda Dezsö
Published: June 2017

In a multiscale modeling approach, we present computer simulation results for a rectifying bipolar nanopore at two modeling levels.
Surface-specific vibrational spectroscopy of the water/silica interface: screening and interference
Authors: Schaefer Jan , Gonella Grazia , Bonn Mischa , Backus Ellen H. G.
Published: June 2017

Surface-specific vibrational sum-frequency generation spectroscopy (V-SFG) is used to obtain information about the molecular structure at charged interfaces.
Exploring surface landscapes with molecules: rotationally induced diffraction of H2 on LiF(001) under fast grazing incidence conditions
Authors: del Cueto M. , Muzas A. S. , Somers M. F. , Kroes G. J. , Díaz C. , Martín F.
Published: June 2017

6D quantum mechanical study of H2 diffraction from LiF(001) as a function of the initial rovibrational state and incidence direction.
Theoretical and experimental studies on three water-stable, isostructural, paddlewheel based semiconducting metal–organic frameworks
Authors: Yang Xiaowei , Zhang Yuan , Li Feng , Guo Tiantian , Wu Yong , Jin Fengyan , Fang Min , Lan Yaqian , Li Yafei , Zhou Yong , Zou Zhigang
Published: June 2017

Theoretical and experimental studies were carried out on three isostructural, water stable, visible light absorbing MOFs, [M2(TCS)(BPY)] (M = Co(1), Ni(2) and Cu(3); H4TCS = tetrakis(4-carboxyphenyl) silane, BPY = 4,4′-bipyridine).
Raman spectral titration method: an informative technique for studying the complexation of uranyl with uranyl(vi)–DPA/oxalate systems as examples
Authors: Liu Qian , Zhang Qianci , Yang Suliang , Zhu Haiqiao , Liu Quanwei , Tian Guoxin
Published: June 2017

Spectral titration method with Raman spectroscopy is a powerful method for studying the complexation of uranyl(vi) with various ligands.
Synthesis and characterization of two layered aluminophosphates [R-C8H12N]8[H2O]2·[Al8P12O48H4] and [S-C8H12N]8[H2O]2·[Al8P12O48H4] with a mirror symmetric feature and their proton conductivity
Authors: Yu Yue , Zhu Jingran , Liu Jiancong , Yan Yan , Song Xiaowei
Published: June 2017

Two homochiral aluminophosphates with a mirror symmetric feature were synthesized. H-bond chains play a key role in chirality and proton conductivity.
Two-dimensional frameworks formed by pentagonal bipyramidal cobalt(ii) ions and hexacyanometallates: antiferromagnetic ordering, metamagnetism and slow magnetic relaxation
Authors: Shao Dong , Zhou Yan , Pi Qian , Shen Fu-Xing , Yang Si-Run , Zhang Shao-Liang , Wang Xin-Yi
Published: June 2017

Two-dimensional frameworks constructed by pentagonal bipyramidal CoII and [M(CN)6]3− units have been synthesized and characterized structurally and magnetically.
Improved degradation of anaerobically digested sludge during post aerobic digestion using ultrasonic pretreatment
Authors: Song Kang , Xie Guo-Jun , Qian Jin , Bond Philip L. , Wang Dongbo , Zhou Beibei , Liu Yiqi , Wang Qilin
Published: June 2017

We propose that ultrasonic pretreatment could significantly improve the degradation of anaerobically digested sludge with economic favorability in post aerobic digestion.
Porous silica-encapsulated and magnetically recoverable Rh NPs: a highly efficient, stable and green catalyst for catalytic transfer hydrogenation with “slow-release” of stoichiometric hydrazine in water
Authors: Zhou Junjie , Li Yunong , Sun Hong-bin , Tang Zhike , Qi Li , Liu Lei , Ai Yongjian , Li Shuang , Shao Zixing , Liang Qionglin
Published: June 2017

A porous core–shell nanocatalyst hydrazine hydrate water system has been developed for the catalytic transfer hydrogenation of nitroarenes.
Sample preparation of lipstick for further Cd and Pb determination by ICP-MS: is the use of complexing acids really necessary?
Authors: Mesko Marcia Foster , La Rosa Novo Diogo , Rondan Filipe Soares , Pereira Rodrigo Mendes , Costa Vanize Caldeira
Published: June 2017

In this work, the use of complexing acids (HF and HCl) combined with HNO3 was evaluated for lipstick digestion and further Cd and Pb determination by ICP-MS.
Magnetically actuated functional gradient nanocomposites for strong and ultra-durable biomimetic interfaces/surfaces
Authors: Wang Zhengzhi , Shi Xiaoming , Huang Houbing , Yao Chenmin , Xie Wen , Huang Cui , Gu Ping , Ma Xingqiao , Zhang Zuoqi , Chen Long-Qing
Published: June 2017

Magnetically-actuated functional gradient nanocomposites can be locally programmed to generate unprecedented mechanical gradients applied to various bioinspired load-bearing materials.
Synthesis, crystal structure and magnetic properties of [Co(bpcam)2]ClO4·dmso·H2O, [Co(bpcam)2]2[Co(NCS)4]·dmso·H2O and [Ni(bpcam)2]·H2O [Hbpcam = bis(2-pyrimidylcarbonyl)amide]
Authors: Rabelo Renato , Valdo Ana K. , Robertson Craig , Thomas Jim A. , Stumpf Humberto O. , Martins Felipe T. , Pedroso Emerson F. , Julve Miguel , Lloret Francesc , Cangussu Danielle
Published: June 2017

Synthesis, crystal structures, spectroscopy and magnetic properties of three new bpcam-containing complexes are presented here.
1,3,5-Tris(2-hydroxyethyl)isocyanurate functionalized graphene oxide: a novel and efficient nanocatalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones
Authors: Dekamin Mohammad G. , Mehdipoor Fatemeh , Yaghoubi Amene
Published: June 2017

The preparation and characterization of a novel 1,3,5-tris(2-hydroxyethyl)isocyanurate functionalized graphene oxide (GO–THEIC) nanomaterial and its catalytic application for the Biginelli reaction are described.
Mechanical and biological investigations of chitosan–polyvinyl alcohol based ZrO2doped porous hybrid composites for bone tissue engineering applications
Authors: Bhowmick Arundhati , Pramanik Nilkamal , Mitra Tapas , Gnanamani Arumugam , Das Manas , Kundu Patit Paban
Published: June 2017

Porous bone-like chitosan–PVA–HAP-ZrO2composites were developed to achieve suitable tensile strengths, antibacterial properties, and cytocompatibility with MG-63 cells.
Upconversion based near white light emission, intrinsic optical bistability and temperature sensing in Er3+/Tm3+/Yb3+/Li+:NaZnPO4 phosphors
Authors: Mukhopadhyay Lakshmi , Rai Vineet Kumar
Published: June 2017

NaZnPO4:Er3+/Tm3+/Yb3+/Li+ phosphors have been prepared which show UC based near white light emission, intrinsic optical bistability and temperature-dependent population re-distribution ability.
Diruthenium(ii,iii) metallodrugs of ibuprofen and naproxen encapsulated in intravenously injectable polymer–lipid nanoparticles exhibit enhanced activity against breast and prostate cancer cells
Authors: Alves Rico Samara R. , Abbasi Azhar Z. , Ribeiro Geise , Ahmed Taksim , Wu Xiao Yu , de Oliveira Silva Denise
Published: June 2017

Stable nanoformulations of diruthenium(ii,iii)-NSAID metallodrugs encapsulated in intravenously injectable polymer-lipid NPs have been prepared and tested in cancer cells.
Nanoporous IrO2 catalyst with enhanced activity and durability for water oxidation owing to its micro/mesoporous structure
Authors: Li Guoqiang , Li Songtao , Xiao Meiling , Ge Junjie , Liu Changpeng , Xing Wei
Published: June 2017

Micro/mesoporous IrO2 catalyst with an ultrahigh specific surface area of 363.3 m2 g−1 shows excellent electrocatalytic performance for the oxygen evolution reaction.
Targeting heparin and heparan sulfate protein interactions
Authors: Weiss Ryan J. , Esko Jeffrey D. , Tor Yitzhak
Published: June 2017

Heparan sulfate is ubiquitously expressed on the cell surface and in the extracellular matrix of all animal cells. These negatively-charged carbohydrate chains play essential roles in many important cellular functions by interacting with various heparan sulfate binding proteins (HSBP). This review discusses methods for targeting these complex biomolecules, as strategies for treating human disease.
t-BuOK-mediated reductive addition of P(O)–H compounds to terminal alkynes forming β-arylphosphine oxides
Authors: Zhang Ji-Shu , Zhang Jian-Qiu , Chen Tieqiao , Han Li-Biao
Published: June 2017

A novel and efficient t-BuOK-mediated reductive addition of P(O)–H compounds to terminal alkynes forming β-arylphosphine oxides was developed. This reaction may proceed via a tandem process involving regio-selective addition and subsequent transfer hydrogenation.
Late-stage divergent synthesis and antifouling activity of geraniol–butenolide hybrid molecules
Authors: Takamura Hiroyoshi , Ohashi Takumi , Kikuchi Takahiro , Endo Noriyuki , Fukuda Yuji , Kadota Isao
Published: June 2017

Hybridization of the geraniol and butenolide structural motifs enhanced the antifouling activity.
Copper(ii)-promoted oxidative C–H/C–H cross-coupling for rapid access to aza-BODIPY-indole derivatives with broad optical absorption
Authors: Jiang Ruyong , Yang Xiuguang , Wu Di
Published: June 2017

The absorption band of aza-BODIPY is remarkably broadened by coupling with indoles via a concise and inexpensive approach.
Effect of conjugation length and metal-backbone interactions on charge transport properties of conducting metallopolymers
Authors: Nguyen Minh T. , Jones Richard A. , Holliday Bradley J.
Published: June 2017

Detailed studies on the effect of organic conjugation length, metal centers, and metal-backbone redox interactions on the charge transport properties of conducting metallopolymers (CMPs) are reported.
Phosphazene/triisobutylaluminum-promoted anionic ring-opening polymerization of 1,2-epoxybutane initiated by secondary carbamates
Authors: Hassouna L. , Illy N. , Guégan P.
Published: June 2017

The deprotonation of secondary carbamates bytBuP2in the presence of a Lewis acid allowed initiating the polymerization of 1,2-epoxybutane.
Ring-opening polymerization of donor–acceptor cyclopropanes catalyzed by Lewis acids
Authors: Hayakawa Kosuke , Matsuoka Shin-ichi , Suzuki Masato
Published: June 2017

Ring-opening polymerization of a variety of cyclopropane derivatives catalyzed by Lewis acids has been investigated.
Li2CdGeSe4and Li2CdSnSe4: biaxial nonlinear optical materials with strong infrared second-order responses and laser-induced damage thresholds influenced by photoluminescence
Authors: Zhang Jian-Han , Clark Daniel J. , Weiland Ashley , Stoyko Stanislav S. , Kim Yong Soo , Jang Joon I. , Aitken Jennifer A.
Published: June 2017

Two new biaxial, diamond-like semiconductors, Li2CdGeSe4and Li2CdSnSe4, were preparedviahigh-temperature, solid-state synthesis.
A carbon based drug delivery system derived from a one-dimensional coordination polymer, doxorubicin loading and redox-responsive release
Authors: Jia Yuan , Xu Xinxin , Ou Jinzhao , Liu Xiaoxia , Shi Fa-nian
Published: June 2017

A redox-responsive drug delivery system has been fabricated through the modification of –S–S– bonds on coordination polymer derived mesoporous carbon nanoparticles with Ag as a “gatekeeper”.
Highly efficient thermally activated delayed fluorescence materials with reduced efficiency roll-off and low on-set voltages
Authors: Zhao Haobin , Wang Zhiheng , Cai Xinyi , Liu Kunkun , He Zuozheng , Liu Xin , Cao Yong , Su Shi-Jian
Published: June 2017

Two carbazole and diphenylamine terminated D–A type molecules were developed as TADF materials, achieving highly efficient blue and green emitting devices with low on-set voltages and reduced efficiency roll-off.
Lignin derived activated carbon particulates as an electric supercapacitor: carbonization and activation on porous structures and microstructures
Authors: Hu Sixiao , Hsieh You-Lo
Published: June 2017

A facile simultaneous carbonation and activation approach to convert lignin to microporous carbon particulates for super capacitors in energy storage.
Hydroquinone derivatives from the marine-derived fungus Gliomastix sp.
Authors: Elnaggar Mohamed S. , Ebrahim Weaam , Mándi Attila , Kurtán Tibor , Müller Werner E. G. , Kalscheuer Rainer , Singab Abdelnasser , Lin Wenhan , Liu Zhen , Proksch Peter
Published: June 2017

A novel cytotoxic quinone/hydroquinone dimer from the marine-derived fungusGliomastixsp.
Sol–gel synthesis of nanosilica-coated para-aramid fibers and their application in the preparation of paper-based friction materials
Authors: Lu Zhaoqing , Hu Wenjing , Xie Fan , Zhuo Longhai , Yang Bin
Published: June 2017

A facile method of surface modification to fabricate nanosilica-coated aramid fibersviasol–gel process and their application for paper-based friction materials by wet-forming process.
Modeling of the formation kinetics and size distribution evolution of II–VI quantum dots
Authors: Lazzari Stefano , Abolhasani Milad , Jensen Klavs F.
Published: June 2017

A population balance model describes the formation of II–VI semiconductor nanocrystals and predicts experimentally observed properties of the nanocrystal size distribution.
RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification
Authors: Ren Xiaojun , Deng Ruijie , Wang Lida , Zhang Kaixiang , Li Jinghong
Published: June 2017

We report a highly sensitive method for quantifying the splicing products in different steps, enabling us to analyze the splicing process and identify ASO inhibitors.
Structural-functional analysis of engineered protein-nanoparticle assemblies using graphene microelectrodes
Authors: Ping Jinglei , Pulsipher Katherine W. , Vishnubhotla Ramya , Villegas Jose A. , Hicks Tacey L. , Honig Stephanie , Saven Jeffery G. , Dmochowski Ivan J. , Johnson A. T. Charlie
Published: June 2017

Nanoparticle-driven current is measured with a graphene electrode for quantifying the pore-size of the ferritin enclosing the nanoparticle.
MD simulations and QM/MM calculations show that single-site mutations of cytochrome P450BM3 alter the active site’s complexity and the chemoselectivity of oxidation without changing the active species
Authors: Dubey Kshatresh Dutta , Wang Binju , Vajpai Manu , Shaik Sason
Published: June 2017

A new water channel appears in the T268A mutant of P450BM3 and plays a role in the enzyme’s chemoselectivity.
Synthesis and evaluation of MR probes for targeted-reporter imaging
Authors: Verma Kirti Dhingra , Massing Justin O. , Kamper Sarah G. , Carney Christiane E. , MacRenaris Keith W. , Basilion James P. , Meade Thomas J.
Published: June 2017

Visualizing disease heterogeneity remains a challenging task since most imaging agents are targeted to a single receptor.
Cross-linking of COOH-containing polymers using Ag(i)-catalyzed oxidative decarboxylation in aqueous solution
Authors: Weng Gengsheng , Huang Yu , Thanneeru Srinivas , Li Hongqiang , Alamri Abdullah , He Jie
Published: June 2017

Ag(i)-Catalyzed oxidative decarboxylation as a new tool offers a facile and high efficient way to cross-link COOH-containing (co)polymers.
Combining catalysis and hydrogen storage in direct borohydride fuel cells: towards more efficient energy utilization
Authors: Chen Jun , Fu Jun , Fu Kai , Xiao Rui , Wu Yong , Zheng Xinyao , Liu Zhiliang , Zheng Jie , Li Xingguo
Published: June 2017

Combining catalysis and hydrogen storage in an electrode promotes the energy utilization efficiency of direct borohydride fuel cells by inhibiting H2 formation.
Fire-resistant tannin–ethylene glycol gels working as rubber springs with tuneable elastic properties
Authors: Delgado-Sánchez C. , Amaral-Labat G. , Grishechko L. I. , Sánchez –Sánchez A. , Fierro V. , Pizzi A. , Celzard A.
Published: June 2017

Non-flammable, tannin-based gels with tuneable elastic properties acting as rubber springs.
Unprecedented low energy losses in organic solar cells with high external quantum efficiencies by employing non-fullerene electron acceptors
Authors: Mishra Amaresh , Keshtov Mukhamed L. , Looser Annika , Singhal Rahul , Stolte Matthias , Würthner Frank , Bäuerle Peter , Sharma Ganesh D.
Published: June 2017

Non-fullerene molecular acceptors in combination with a polymeric donor gave well performing BHJSCs with energy losses below 0.4 eV concomitant with outstanding external quantum efficiencies in the NIR-regime.
Bright X-ray and up-conversion nanophosphors annealed using encapsulated sintering agents for bioimaging applications
Authors: Chen Hongyu , Wang Fenglin , Moore Thomas L. , Qi Bin , Sulejmanovic Dino , Hwu Shiou-Jyh , Mefford O. Thompson , Alexis Frank , Anker Jeffrey N.
Published: June 2017

Nanophosphors are promising contrast agents for deep tissue optical imaging applications because they can be excited by X-ray or near infrared light through tissue without background interference.
Tunable control efficiency of patterned nucleation by post-annealing
Authors: Wang Hong , Zhang Congyun , Zhu Juan , Fontein Florian , Wang Yandong , Wang Yue , Fuchs Harald , Wang Wenchong , Chi Lifeng
Published: June 2017

Functional organic structures with tunable spacing from sub-micrometer to tens of micrometers were obtained by post-annealing.
Characterization of an androgen-responsive, ornithine decarboxylase-related protein in mouse kidney
Authors: Silander Kristian M. , Pihlajamaa Päivi , Sahu Biswajyoti , Jänne Olli A. , Andersson Leif C.
Published: June 2017

We have investigated and characterized a novel ornithine decarboxylase (ODC) related protein (ODCrp) also annotated as gm853. ODCrp shows 41% amino acid sequence identity with ODC and 38% with ODC antizyme inhibitor 1 (AZIN1). The Odcrp gene is selectively expressed in the epithelium of proximal tubuli of mouse kidney with higher expression in males than in females. Like Odc in mouse kidney, Odcrp is also androgen responsive with androgen receptor (AR)-binding loci within its regulatory region. ODCrp forms homodimers but does not heterodimerize with ODC. Although ODCrp contains 20 amino acid residues known to be necessary for the catalytic activity of ODC, no decarboxylase activity could be found with ornithine, lysine or arginine as substrates. ODCrp does not function as an AZIN, as it neither binds ODC antizyme 1 (OAZ1) nor prevents OAZ-mediated inactivation and degradation of ODC. ODCrp itself is degraded via ubiquination and mutation of Cys363 (corresponding to Cys360 of ODC) appears to destabilize the protein. Evidence for a function of ODCrp was found in ODC assays on lysates from transfected Cos-7 cells where ODCrp repressed the activity of endogenous ODC while Cys363Ala mutated ODCrp increased the enzymatic activity of endogenous ODC.
Towards multispectral, multi‐sensor indoor positioning and target identification
Authors: Kaasalainen S. , Ruotsalainen L. , Kirkko‐Jaakkola M. , Nevalainen O. , Hakala T.
Published: June 2017

A concept and first results of combining multispectral light detection and ranging (LiDAR) with positioning sensors to produce spatially resolved target identification in indoor environment is presented. The aim is to enhance the sensor‐based indoor localisation with a multispectral target identification and mapping. There is a growing need for automatic and mobile mapping and surveillance in buildings and locations where satellite positioning is not available. LiDAR is a common sensor in feature‐based simultaneous localisation and mapping. As multispectral LiDARs are emerging and becoming increasingly popular in research applications, the multi/hyperspectral point clouds are likely to improve object recognition and enable a new level of autonomous surveillance in the near future. The first results show that position solution can be obtained using sensors attached to the LiDAR.
Role for 2D image generated 3D face models in the rehabilitation of facial palsy
Authors: Storey Gary , Jiang Richard , Bouridane Ahmed
Published: June 2017

The outcome for patients diagnosed with facial palsy has been shown to be linked to rehabilitation. Dense 3D morphable models have been shown within the computer vision to create accurate representations of human faces even from single 2D images. This has the potential to provide feedback to both the patient and medical expert dealing with the rehabilitation plan. It is proposed that a framework for the creation and measuring of patient facial movement consisting of a hybrid 2D facial landmark fitting technique which shows better accuracy in testing than current methods and 3D model fitting.
Secured remote health monitoring system
Authors: Sathya Duraisamy , Ganesh Kumar Pugalendhi
Published: June 2017

Wireless medical sensor network is used in healthcare applications that have the collections of biosensors connected to a human body or emergency care unit to monitor the patient's physiological vital status. The real‐time medical data collected using wearable medical sensors are transmitted to a diagnostic centre. The data generated from the sensors are aggregated at this centre and transmitted further to the doctor's personal digital assistant for diagnosis. The unauthorised access of one's health data may lead to misuse and legal complications while unreliable data transmission or storage may lead to life threatening risk to patients. So, this Letter combines the symmetric algorithm and attribute‐based encryption to secure the data transmission and access control system for medical sensor network. In this work, existing systems and their algorithm are compared for identifying the best performance. The work also shows the graphical comparison of encryption time, decryption time and total computation time of the existing and the proposed systems.
Class of novel broadband chaos‐based coherent communication systems
Authors: Jovic Branislav
Published: June 2017

As opposed to chaotic communication systems where a message signal directly modulates a broadband chaotic signal, it is also possible to indirectly utilise a chaotic signal to form a chaos‐based communication system. This study proposes a class of novel broadband chaos‐based coherent communication systems and demonstrates that their theoretical probability of error expressions match those of their counterpart conventional narrowband systems in the additive white Gaussian noise and the Rayleigh flat fading channel. The results are confirmed with the corresponding empirical bit error rate (BER) simulations. It is demonstrated that the chaos‐based quadrature phase shift keying system offers an overall best performance while the chaos‐based amplitude shift keying and frequency shift keying equivalent systems offer a possibility of performance optimisation. Most importantly, it is shown that the proposed systems outperform the chaotic communication systems in terms of BER while also being more practicable. The proposed systems thus hold high promise as the chaotic communication systems pose implementation difficulties, lack robust synchronisation techniques and are generally considered of academic interest only.