bluuebunny/crossref_metadata_2025 huggingface dataset:
Gejala dan komorbid yang memengaruhi mortalitas pasien positif COVID-19 di Jakarta Timur, Maret-September 2020
Authors: Drew Clement , Adisasmita Asri C
Published: December 2022

Penyakit oleh virus SARS-CoV2 yang menyerang sistem pernapasan telah menjadi pandemi sejak Februari 2020 dan di Indonesia sejak Maret 2020. Penting untuk mengidentifikasi faktor risiko yang meningkatkan risiko mortalitas dalam kasus ini. Studi analitik dengan desain kohort retrospektif dari data penelusuran epidemiologis oleh Dinas Kesehatan Provinsi DKI Jakarta di Jakarta Timur sejak bulan Maret - September 2020. Dari total data yang didapatkan (8393 sampel), terdapat 212 (2.53%) orang yang meninggal. Analisis data multivariat dengan regresi logistik menemukan bahwa jenis kelamin laki-laki meningkatkan RR mortalitas sebesar 2.15 (95% IK: 1.47-3.14), usia ?60 tahun sebesar 4.49 (95% IK: 3.05-6.63), adanya gejala saluran pernapasan sebesar 2.17 (95% IK: 1.26-3.72), adanya gejala luar saluran pernapasan sebesar 2.47 (95% IK: 1.43-4.29), riwayat hipertensi sebesar 2.45 (95% IK: 1.46-4.10) dan riwayat gagal ginjal kronik sebesar 3.33 (95% IK: 1.27 - 8.68). Dari hasil studi ini dapat disimpulkan bahwa jenis kelamin, usia, gejala saluran pernapasan, gejala luar saluran pernapasan, riwayat hipertensi dan gagal ginjal kronik meningkatkan risiko mortalitas pasien positif COVID-19 di Jakarta Timur.
Hubungan durasi mengemudi dengan risiko suspect carpal tunnel syndrome pada ojek online
Authors: Sari Mutiara Fatika , Novendy Novendy
Published: December 2022

Salah satu penyakit akibat kerja yang sering terjadi adalah carpal tunnel syndrome (CTS). Faktor-faktor yang berpengaruh adalah postur pergelangan tangan dalam keadaan fleksi dan ekstensi yang terlalu ekstrim, penggunaan otot fleksi repetitif, dan tereksposnya pergelangan tangan terhadap getaran dalam jangka waktu lama. Pengemudi ojek online merupakan salah satu pekerjaan yang berpotensi lebih mudah dan sering mengalami paparan. Saat mengendarai motor, tangan melakukan gerakan yang bersifat repetitif dengan postur pergelangan tangan dalam keadaan fleksi maupun ekstensi saat memegang handle bar (setang). Tujuan dari studi ini untuk mengetahui hubungan durasi mengemudi dengan suspect carpal tunnel syndrome pada pengemudi ojek online sehingga dapat dilakukan pencegahan di kemudian hari. Studi ini menggunakan metode analitik observasional dengan pendekatan potong lintang. Instrument yang digunakan berupa Boston Carpal Tunnel Syndrome Questionnaire (BCTQ). Total jumlah responden pada studi ini adalah 193 orang. Berdasarkan data durasi mengemudi, terdapat 118 (61,1%) responden mengemudi ? 10 jam/hari responden, dan 75 (38.9%) responden selama <10 jam/hari.  Sebanyak 93 (78.8%) responden memiliki suspect CTS dan 25 (21.2%) responden tidak memiliki suspect CTS. Berdasarkan analisis bivariat, didapatkan p-value  0.949 dan PR 1.019,  yang berarti tidak ada hubungan yang bermakna antara durasi mengemudi dengan risiko suspect carpal tunnel syndrome pada ojek online.
Analisis cross reactivity protein precursor membrane (prM) virus dengue endemik Indonesia dengan pendekatan imunoinformatik
Authors: Hasan Rizqy Lazuardy , Sidarta Erick
Published: December 2022

Infeksi demam berdarah dianggap sebagai salah satu masalah kesehatan utama di Indonesia dan disebabkan oleh virus dengue. Kemampuan reaksi silang pada virus dengue dapat memperparah jika terjadi infeksi lainnya. Protein precursor membrane (prM) pada virus dengue merupakan bagian yang rentan akan terjadinya antibody dependant enhancement dan evolusi gen prM berubah setiap tahunnya. Studi ini bertujuan untuk menganalisa reaksi silang gen prM dari virus dengue yang endemis di Indonesia. Sebanyak 96 data sampel dari National Center for Biotechnology Information digunakan pada studi ini. Prediksi antigenisitas dengan metode B-cell epitope prediction lalu di lanjutkan proses analisis reaksi silang menggunakan Basic Local Aligntment Search Tool (BLAST) dengan perbagian 20 protein prM pada setiap genotype virus yang memiliki antigenisitas yang spesifitasnya 0,8. Hasil dari studi ini didapatkan 4 prediksi antigenisitas dan beberapa hasil reaksi silang terhadap protein lain seperti anti-SARS-CoV-2 immunoglobulin heavy chain, human immunodeficiency virus type I enhancer-binding protein 2, insulin receptor substrate like protein partial, cerebellar-degeneration-related antigen. Pada studi ini ditemukan adanya perubahan prediksi antigenisitas dari gen prM virus dengue yang muncul setiap tahun dan adanya reaksi silang dengan protein lain.
ANALISIS RISIKO PETERNAKAN AYAM PEDAGING SUPRIADI FARM
Authors: Pratiwi Luvy Eka , Suprapti Isdiana
Published: December 2022

Peternakan Supriadi Farm merupakan salah satu peternakan yang ada di Kecamatan Loceret, Kabupaten Nganjuk. Peternakan ini membudidayakan ayam pedaging terbanyak sebesar 25.000 ekor ayam. Tujuan penelitian ini yakni mengidentifikasi sumber risiko; menganalisis tingkat peluang, dampak, & peta risiko; dan strategi penanganan risiko bisnis yang ada di peternakan Supriadi Farm. Menggunakan metode analisis data Fishbone, Z-Score, dan Value at Risk. Hasil penelitian ini terdapat tiga sumber risiko yaitu risiko produksi, risiko pemasaran, dan risiko keuangan. Risiko produksi memiliki probabilitas yang besar namun berdampak rendah, risiko pemasaran memiliki probabilitas yang besar namun berdampak rendah, dan risiko keuangan yang bersumber dari sumber dana memiliki probabilitas dan dampak risiko yang kecil, sedangkan yang bersumber dari biaya dan pendapatan memiliki probabilitas tinggi dan dampak yang kecil. Strategi penanganan pada peternakan Supriadi Farm ini adalah strategi preventif.
La metodología de evaluación en AEVAL
Authors: Rico Callado Javier
Published: December 2022

El artículo analiza la metodología diseñada y aplicada por la Agencia Estatal de Evaluación de Políticas Públicas y la Calidad de los Servicios en la evaluación de programas y políticas públicas a lo largo de sus años de existencia (2007-2017). Una metodología ecléctica, principalmente pluralista, aunque adoptando parcialmente otras perspectivas y paradigmas. Fue el fruto de un aprendizaje y práctica de evaluación continuo. Se reflexiona sobre distintos elementos institucionales y organizativos que condicionaron tanto su metodología como su práctica evaluativa. Se analiza el diseño de las evaluaciones de AEVAL, con especial referencia a los métodos y técnicas utilizados, y su proceso de evaluación. Finalmente se destacan algunas de las fortalezas y debilidades de la metodología de la Agencia.
"Ándate al páramo": prácticas lingüísticas de exclusión y prejuicios en contra de los indígenas en la interacción interétnica en Twitter (Ecuador)

Authors: Placencia Maria Elena
Published: December 2022

Este artículo examina las prácticas lingüísticas de usuarios de Twitter mediante las cuales se intenta discriminar y excluir a indígenas en el contexto ecuatoriano y los prejuicios detrás de estas prácticas.  Para el estudio se seleccionaron las cuentas de tres líderes indígenas, activos en Twitter, y se construyó un corpus basado en las respuestas que los usuarios dan a los tuits de estos líderes (2944 respuestas); se recogieron los datos en un período de tiempo durante de las elecciones presidenciales de 2021. El enfoque adoptado es el de la pragmática crítica al buscar desvelar prácticas discriminatorias en contra de minorías, tomando en cuenta en este caso el contexto histórico y político de su ocurrencia. Partiendo de trabajos sobre agravios (‘slurs’) (ej. Croom 2011) e insultos raciales (ej. Guimarães 2003), se identificaron 329 instancias de este tipo de insultos, que luego se agruparon temáticamente, de acuerdo con las creencias negativas sobre la identidad indígena que parecen (re)crear (ej. que los indígenas son ignorantes, que no tienen higiene, etc.). El estudio muestra que el racismo a través del lenguaje, que se ha observado en interacciones cara a cara (v. p. ej., De la Torre 2002; Placencia 2008) se ha extendido en línea, con diversas manifestaciones, tanto convencionales como no convencionales y parece ocurrir sin freno en la plataforma.
Fuzzy Translation and Fuzzy Multiplication on D-Algebras
Authors: Mohammed Khalid Shahoodh  , Montaser I. Adwan
Published: December 2022

The concept of fuzzy set (FS) is one of the beautiful branches in Mathematics. This concept was initiated by Zadeh [1]. Since that time, many studies have been considered this concept by different ways in the field of pure and applied Mathematics. In this article, we introduced the notion of FT and FM on a D-algebras where FT is a fuzzy Translation and FM is a fuzzy Multiplication. We proved some characterizations of FT and FM of sub-algebra and d-ideal of a D-algebras  Moreover, the notion of FM-αλ-T has been investigated on the D-algebras  Furthermore, some results on the d-homomorphism of FT and FM which based on the fuzzy d-ideal of a D-algebras are presented.
The validity of limestone rocks belonging to the Pila Spi and Sinjar formations within the Bazian fold / Sulaymaniyah governorate for riprap purposes
Authors: Maher Najm Abdullah  , Mohammed Rashid Abood  , Amera Ismael Hussain
Published: December 2022

The study aims to know some of the physical and mechanical properties of limestone rocks within the Pila Spi and Sinjar Formations at the southwestern limb of Bazian Fold within the Sulaymaniyah Governorate, in order to show their suitability as riprap stones. The tests showed that the values ​​of the dry density of these rocks ranged between (1.857-2.341) g/cm³, the water absorption rate ranged from (1.848-9.87)%, and the specific weight ranged from (2.167-2.255), and the values ​​of the chemical erosion ratio ranged between (8.9-29)%. After knowing the physical and mechanical properties of these limestone rocks and comparing them with the standard specifications of the riprap stones, it was found that these rocks are not suitable for riprap purposes in all the stations of the study area most of the stations of the study area.
Effectiveness of the plant growth regulator Setar, SC* in spring rapeseed cultivation on leached chernozem of the Krasnodar region
Authors:   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Tishkov N.M. , Tilba V.A. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Makhonin V.L. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Shkarupa M.V. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops
Published: December 2022

The productivity of spring rapeseed plants is significantly affected by the weather conditions of the growing season and the phytosanitary condition of the sowings. Plant growth regulators can increase crop resistance to environmental stress factors and pathogens. Combined application of plant growth regulators and fungicides is also an effective technique in rapeseed cultivation. In 2020–2021, on leached chernozem of the Krasnodar region, we studied the effectiveness of plant growth regulator Setar, SC during the cultivation of a spring rapeseed variety Tavrion. Setar, SC is a combination of a plant growth regulator paclobutrazol and a systemic fungicide difenoconazole. Spraying of rapeseed plants with Setar, SC preparation at the budding stage in doses 0.3, 0.4, and 0.5 l/ha has increased the preservation of the plant density by the harvesting time by 3.2–6.5 %, number of pods on plants – by 6.0–13.6, seeds – by 5.8–8.5, and thousand-seed weight – by 3.4–4.3 %. The application of preparation did not significantly affect the oil content of seeds of spring rapeseed. Due to the positive impact on the yield structure elements, the treatment of plants with the growth regulator Setar, SC resulted in the increase of seed yield of spring rapeseed by 0.15–0.22 t/ha and oil yield by 61–93 kg/ha on av-erage during the two years of research. The multiple correlation and regression analysis revealed the dependence of the yield of spring rapeseed variety Tavrion on the number of plants per 1.0 m2 and the number of seeds on the plants per 1.0 m2 with the impact proportions of 69.4 and 21.4 %, respectively. The optimal dose for spraying the spring rapeseed plants at the budding stage with Setar, SC preparation in the conditions of the central natural and climatic zone of the Krasnodar region was 0.4 l/ha.
The effect of copper and zinc fertilizers on sowing qualities of winter wheat seeds
Authors:   I.T. Trubilin Kuban State Agrarian University, Onishchenko L.M. , Golubova V.C. ,   I.T. Trubilin Kuban State Agrarian University, Razgulin V.A. ,   I.T. Trubilin Kuban State Agrarian University, Ali Ali Kadem A.  ,   I.T. Trubilin Kuban State Agrarian University
Published: December 2022

We studied the optimal concentrations of copper and zinc fertilizers for presowing treatment of seeds of winter soft wheat, which improve their sowing qualities and growth activity of seedlings of the crop. Zinc (ZnSO4 • 7H2O) and copper (CuSO4 • 5H2O) microfertilizers have a versatile effect on the control samples. At 0.005 % concentration of Zn and Cu, the activity of seed germination was significantly improved to 54.9 and 56.5 %, laboratory seed germination was increased to 94 and 95 %, seed germination rate was up to 3.2 and 3.4 days, germination uniformity was up to 8.7 and 9.2 pcs/day, respectively. Under the influence of CuSO4 • 5H2O containing 0.5 and 0.05 % Cu, the length of seedling roots tended to decrease, but at a concentration of 0.005 and 0.0005 %, this indicator significantly increased. The average dry weight of roots at a Zn concentration of 0.005 % was the highest – 1.98 g, which is 1.84 g higher than the control. Presowing treatment of seeds of winter soft wheat with a water solution of CuSO4 • 5H2O or ZnSO4 • 7H2O containing 0.005 % Cu or Zn improves the sowing qualities of seeds of the crop, which will subsequently allow realizing the genetic potential of the high-yielding variety of winter soft wheat Bezostaya 100, widely used in grain production.
Desmitificando atendimento odontológico em gestantes: uma revisão narrativa
Authors: Silva Izabella Corrêa da , Araújo Ivanna Rosa Barbosa Costa de , Palma Daniela Ignacia Rivera , Silva Lucimara Rocha da , Acioly Gabrielly Maria Argolo , Araújo Ana Júlia da Silva , Peixoto Fernanda Braga , Peixoto Marcílio Otávio Brandão
Published: December 2022

Objetivo: Realizar uma revisão de literatura sobre o atendimento odontológico no período gestacional. Revisão Bibliográfica: O atendimento clínico odontológico pode e deve ser realizado em qualquer período durante a gestação, tendo em vista que é mais prejudicial para o bebê o fato da mãe continuar com infecções na cavidade bucal do que a realização do tratamento. O conhecimento do cirurgião-dentista em relação às características de cada trimestre gestacional é de fundamental importância durante o atendimento dessas pacientes, além da realização de uma boa anamnese a fim de instituir um bom plano de tratamento, acarretando uma maior relação de confiança entre profissional e paciente. Considerações finais: Com a realização desse estudo foi possível observar que a maioria dos medicamentos utilizados na odontologia não é contra-indicada durante a gestação, estes podem ser prescritos tranquilamente quando necessários e se preciso deve ser feita em parceria com o médico.
One step closer to having diabetes under control
Authors: Kintzinger Mélanie
Published: December 2022

Type 1 diabetes is a chronic disease that requires patients to control their blood sugar levels daily. A drug being tested on newly diagnosed patients could improve their quality of life by protecting and stimulating the pancreatic cells responsible for blood sugar regulation.
Pengaruh Metanol dalam Produksi Biodiesel dari Tamanu Oil Menggunakan Katalis Lipase
Authors: Aznury Martha , Zikri Ahmad , Junaidi Robert , Lupikawaty Marieska , Oktariyensi Chintia
Published: December 2022

Biodiesel is a fuel derived from renewable sources, wich can be used efficiently in petrodiesel engines. This study aims to produce biodiesel from tamanu oil enzymatically using the lipase enzyme. This enzimatic method has a high value product made during the production of biodiesel. Biodiesel production through the transesterification process with methanol reactant and alkaline catalysts has many weaknesses, namely the presence of a saponification reaction and it is difficult to separate because the catalyst is homogeneus. The result of this study indicate that tamanu oil has been seccessfully converted into biodiesel with an optimum oil : methanol molar ratio of 1:5 and a yield precentage of 87,67% with a methyl ester content of 97,37%
MORTAR – A Rich Client Application for in silico Molecule Fragmentation
Authors: Bänsch Felix , Schaub Jonas , Sevindik Betül , Behr Samuel , Zander Julian , Steinbeck Christoph , Zielesny Achim
Published: December 2022

Developing and implementing computational algorithms for the extraction of specific substructures from molecular graphs (in silico molecule fragmentation) is an iterative process. It involves repeated sequences of implementing a rule set, applying it to relevant structural data, checking the results, and adjusting the rules. This requires a computational workflow with data import, fragmentation algorithm integration, and result visualisation. The described workflow is normally unavailable for a new algorithm and must be set up individually. This work presents an open Java rich client Graphical User Interface (GUI) application to support the development of new in silico molecule fragmentation algorithms and make them readily available upon release. The MORTAR (MOlecule fRagmenTAtion fRamework) application visualises fragmentation results of a set of molecules in various ways and provides basic analysis features. Fragmentation algorithms can be integrated and developed within MORTAR by using a specific wrapper class. In addition, fragmentation pipelines with any combination of the available fragmentation methods can be executed. Upon release, three fragmentation algorithms are already integrated: ErtlFunctionalGroupsFinder, Sugar Removal Utility, and Scaffold Generator. These algorithms, as well as all cheminformatics functionalities in MORTAR, are implemented based on the Chemistry Development Kit (CDK).
Análisis de los planes de estudio y el ejercicio profesional de la ingeniería industrial en los países de la Alianza del Pacífico
Authors: Gonzáles Araujo Luis Alberto , Jaimes Suárez Sonia Alexandra , Patiño Nieto Luz Marina , Voelkl Peñaloza Joseph , Rico Restrepo Carolina
Published: December 2022

El presente documento es producto del trabajo colaborativo en REDIN, la red de programas de ingeniería industrial del nodo centro de Colombia de ACOFI, y el resultado de un proyecto de investigación articulado con el Consejo Profesional Nacional de Ingeniería para revisar oportunidades dentro de los programas y el ejercicio profesional de los ingenieros industriales en los países pertenecientes a la Alianza del Pacífico (AP). Este documento analiza los elementos indispensables para la articulación de los programas de Ingeniería Industrial y el ejercicio profesional del ingeniero industrial en los diferentes países de la AP. Este estudio se plantea como punto de partida o lineamiento para resaltar la importancia y necesidad de la licencia profesional como eje fundamental para el ejercicio profesional a nivel internacional y para articular las distintas tendencias en educación e investigación en Ingeniería Industrial. Finalmente, el documento incorpora acciones para el fomento y desarrollo del estudio de los aspectos necesarios para estandarizar los criterios y parámetros para el ejercicio de la ingeniería colombiana en otros escenarios internacionales.
Evaluación logística de una PYME como estrategia para su desempeño organizacional
Authors: Del Ángel-Coronel Anice , Hernández-Osorio Ernestina , Sánchez-Galván Fabiola , García-Rodríguez Rogelio
Published: December 2022

La presente investigación estudia una pyme mexicana, dedicada a la fabricación de productos de limpieza ecológicos y de cuidado personal, con un enfoque logístico que permita analizar su cadena de suministro e identificar áreas de oportunidad. La metodología incluyó la recolección de datos, el análisis de la cadena de suministro, la evaluación logística, la revisión de indicadores logísticos de gestión y almacén, así como la implementación del modelo SCOR interpretado en tres niveles de procesos (superior, configuración y de elementos), cada uno evaluado por indicadores clave de desempeño. Cada indicador fue dividido en atributos de rendimiento (flexibilidad, activos, velocidad de atención, fiabilidad en cuestión de cumplimiento y costos). Se aplicó la herramienta DNA Logistik con el propósito de detectar el nivel de madurez y riesgo de las operaciones logísticas. Como resultado, se identifica la relevancia de cinco funciones logísticas en la cadena de suministro (aprovisionamiento, producción, almacenaje, transporte, venta omnicanal), además, se compararon los resultados con 326 registros de otras pymes en DNA Logistik en el sector de comercio al por menor
Descripción de prácticas de administración de operaciones aplicadas a la gestión de servicios hospitalarios: un análisis de la literatura
Authors: Sánchez Suárez Yasniel , Estupiñán López Shabelis de la Caridad , Marqués León Maylín , Hernández Nariño Arialys , Medina León Alberto Arnaldo
Published: December 2022

La gestión de instituciones hospitalarias cada vez es más compleja. La situación actual exige la eliminación de los modelos de gestión funcionales por operativos que integren de manera simultánea las funciones preventivas, curativas y directivas de manera eficiente con el fin de elevar la calidad asistencial. El objetivo del presente artículo es analizar la evolución de las prácticas en gerencia de procesos en la administración de servicios hospitalarios. Entre los métodos de investigación utilizados se encuentran a revisión bibliográfica y documental, la observación científica participativa, las entrevistas y la observación de los procesos que permiten determinar variables clave para el análisis de modelos. Todo ello se complementa con un análisis bibliométrico cuantitativo-descriptivo de las principales aplicaciones de las funciones de administración de operaciones en los sistemas hospitalarios. Se determinan las funciones más utilizadas en los modelos hospitalarios y su influencia en la calidad de los procesos asistenciales.
Influencia de la posición del sensor MQ-6 y el tiempo transcurrido en la detección de concentración de GLP en una fuga doméstica
Authors: Bueno Vera Alejandro , Luis Ortiz Gianfranco , Taquía Gutiérrez José Antonio
Published: December 2022

Las fugas de gas en Lima e Ica (Perú) aumentan cada año, provocando accidentes y daños irreparables para la población. En esta investigación se produjo una fuga controlada usando una cocina de dos hornillas y un arreglo de sensores MQ-6 dispuestos en distintos ángulos con respecto a la cocina (45°, 0° y 30 °). Se encontró que, si la cocina se ubica en la posición alta (87 cm), la concentración detectada es menor, pero la detección es más rápida (6,419 s) si el arreglo se ubica a 50 cm del origen de la fuga. El tiempo de detección se encuentra entre 13,515 s y 21,740 s y la máxima concentración detectada es de 98 ppm. El modelo de aprendizaje que mejor se adaptó es Support Vector Machine, con un RMSE de 4,61 ppm. Se concluye que la mejor posición para la detección de gas fue a una altura de 47 cm sobre el suelo, a una distancia de 50 cm del sensor y a un ángulo de 0°. El tiempo de detección es de 13,84 s. Por último, se concluye que 30 segundos de fuga no son suficientes para alcanzar el límite dañino (147 ppm).
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter
Authors: Akino Shogo , Yasujima Tomoya , Yamashiro Takahiro , Yuasa Hiroaki
Published: December 2022

Disrupted in renal carcinoma 2 (DIRC2) has gained interest because of its association with the development of renal cancer and cosegregation with a chromosomal translocation. It is a member of the SLC49 family (SLC49A4) and is considered to be an electrogenic lysosomal metabolite transporter; however, its molecular function has not been fully defined. To perform a detailed functional analysis of human DIRC2, we used a recombinant DIRC2 protein (DIRC2-AA), in which the N-terminal dileucine motif involved in its lysosomal localization was removed by replacing with dialanine for redirected localization to the plasma membrane, exposing intralysosomal segments to the extracellular space. The DIRC2-AA mutant induced the cellular uptake of pyridoxine (vitamin B6) under acidic conditions when expressed transiently in COS-7 cells. In addition, uptake was markedly inhibited by protonophores, indicating its function through an H+-coupled mechanism. In separate experiments, the transient overexpression of unmodified DIRC2 (tagged with HA) in human embryonic kidney 293 cells reduced cellular pyridoxine accumulation induced by transiently introduced human thiamine transporter 2/SLC19A3 (tagged with FLAG), a plasma membrane thiamine transporter that also transports pyridoxine. The cellular accumulation of pyridoxine in Caco-2 cells as a cell model was increased by the knockdown of endogenous DIRC2. Overall, the results indicate that DIRC2 is an H+-driven lysosomal pyridoxine exporter. Its overexpression leads to a reduction in cellular pyridoxine accumulation associated with reduced lysosomal accumulation and, conversely, its suppression results in an increase in lysosomal and cellular pyridoxine accumulation.
Kepastian Hukum Pelaksanaan Voting Online Rencana Perdamaian Dalam Penundaan Kewajiban Pembayaran Utang
Authors: Cindarbumi Berlian Pramesthi , Suryamah Aam
Published: December 2022

The purpose of this study is to analyze the legal certainty of implementation voting online for reconcilliation agreement in the suspension of payment scheme. During the Covid-19Pandemic, the government issued various policies regarding social activities that would be carried out in court which were carried out online, now they can be carried out online, including the agenda for voting for reconcilliation agreement in PKPU. However, there is no legal basis for voting online for reconcilliation agreement in PKPU, so there is legal uncertainty regarding this implementation. The research method used in this research is normative juridical. The results of the research obtained are that there is certainty from the implementation of voting online for reconciliation agreement in the suspension of payment scheme by referring to SEMA No. 1 of 2020 as legitimacy which states that judges can carry out activities in court boldly in order to reduce the spread of Covid-19. The implementation of the online voting online for reconciliation agreement as a whole still refers to the UU KPKPU and thats derivative regulations. The novelty of this research is to examine the validity or legal certainty of the implementation of the voting online for reconcilliation agreement in PKPU scheme.

Penelitian ini bertujuan untuk menganalisis kepastian hukum dari pelaksanaan voting online rencana perdamaian dalam skema penundaan kewajiban pembayaran utang (PKPU). Pada masa pandemi Covid-19, pemerintah mengeluarkan berbagai kebijakan mengenai pembatasan sosial yang mengakibatkan kegiatan di pengadilan yang semula dilaksanakan secara langsung, kini dapat dilakukan secara daring, termasuk agenda voting rencana perdamaian dalam PKPU. Akan tetapi, tidak ditemukan landasan hukum dari voting online rencana perdamaian dalam PKPU, sehingga terdapat ketidakpastian hukum terhadap pelaksanaannya. Metode penelitian yang digunakan dalam penelitian ini adalah yuridis normatif. Hasil penelitian yang didapat ialah bahwa terdapat kepastian hukum dari pelaksanaan voting online rencana perdamaian dalam skema PKPU dengan merujuk kepada SEMA No. 1 Tahun 2020 sebagai legitimasi yang menyebutkan bahwa hakim dapat menyelenggarakan kegiatan-kegiatan di pengadilan secara daring demi menekan angka penyebaran Covid-19. Adapun pelaksanaan dari voting online rencana perdamaian secara keseluruhan masih merujuk kepada UU KPKPU dan peraturan turunannya. Kebaruan dari penelitian ini ialah mengkaji keabsahan atau kepastian hukum terhadap pelaksanaan voting rencana perdamaian secara online dalam skema PKPU.

 
Pentingnya Kepemilikan Sertifikat Tanah Melalui Pendaftaran Tanah Sebagai Bukti Hak
Authors: Masriani Yulies Tiena
Published: December 2022

This study aims to find out and analyze how the process of certifying state land into land rights and what obstacles are faced in certifying state land into land rights to land use using normative juridical research methods. The results of the study explained that certifying the land and reversing the name of the land in the name of the certificate owner is an important thing for the community to do to avoid legal problems or minimize risks in the future. With the issuance of a certificate of land rights, the owner is given legal certainty and legal protection to prevent legal disputes that occur in the future as a result of parties who feel aggrieved because of the issuance of a land certificate. One of the land problems that often arises in the community is land disputes or land struggles between parties. One way that can be used to minimize land disputes that occur both between communities and communities with the government is to enforce legal regulations, in the form of clear laws in order to provide legal certainty to the legal owners of land rights, and also laws that are coercive and regulate in order to create order in society. The existence of land registration as proof of rights is legal proof of land ownership. Apart from being proof of ownership, the legality aspect is also to provide certainty to the parties that there is a legal owner of the land.

Penelitian ini bertujuan untuk mengetahui dan menganalisis bagaimana proses pensertifikatan tanah negara menjadi tanah hak dan apa kendala yang dihadapi dalam melakukan pensertifikatan tanah negara menjadi tanah hak terhadap pemanfaatan tanah yang dengan menggunakan metode penelitian yuridis normatif. Adapun hasil penelitian menjelaskan bahwa pensertifikatan tanah dan membalik nama tanahnya atas nama pemilik sertifikat adalah hal yang penting dilakukan masyarakat agar terhindar dari permasalahan hukum atau meminimalisir resiko dikemudian hari. Diterbitkannya sertifikat hak atas tanah, maka kepada pemiliknya diberikan kepastian hukum dan perlindungan hukum untuk mencegah adanya sengketa gugatan hukum yang terjadi dikemudian hari akibat dari adanya pihak yang merasa dirugikan karena terbitnya suatu sertifikat tanah. Salah satu permasalahan tanah yang sering muncul dalam masyarakat yakni sengketa tanah atau perebutan tanah antar pihak. Adapun salah satu cara yang dapat digunakan untuk meminimalisir sengketa tanah yang terjadi baik antar masyarakat ataupun masyarakat dengan pemerintah ialah dengan menegakkan peraturan hukum, berupa hukum yang jelas agar dapat memberikan kepastian hukum kepada pemilik sah hak atas tanah tersebut, dan juga hukum yang bersifat memaksa dan mengatur guna terciptanya ketertiban dalam masyarakat. Pendaftaran tanah sebagai bukti hak merupakan bukti legal kepemilikan tanah. Selain sebagai bukti kepemilikan, aspek legalitas juga untuk memberikan kepastian kepada para pihak bahwa ada pemilik yang sah atas tanah tersebut.

 

 

 
A Curvilinear Approach to Psychological Capital and Adaptive Behavior in Firefighters: Focused on the Cross-level Moderating Role of Team Communication
Authors:   Korean Academy Of Management, Lee Kyoungae , Kim Hack-Soo
Published: December 2022

Former studies have shown that psychological capital — a key variable in positive psychology and positive organizational behavior approach — exerts a consistently positive effect. However, recent research has begun to raise doubts about whether job outcomes are always desirable when positive emotions and cognitions are high. In this vein, this research — apart from the linear argument that the higher the psychological capital, the higher the adaptive behavior — empirically explores the idea that psychological capital might result in negative effects if it exceeds a certain level. Additionally, we examine team communication as a way to effectively manage these negative effects.
Analysis of data collected from 62 firefighter team leaders and 261 firefighters finds that psychological capital has an inverted U-shaped non-linear effect on adaptive behavior. That is, from a low level to a certain level of psychological capital, psychological capital and adaptive behavior show a positive relationship.
Conversely, when psychological capital exceeds a certain level, the relationship between psychological capital and adaptive behavior is negative. We also find that when team communication is sufficiently high, there is a cross-level moderating effect that lessens the inverted U-shaped curvilinear relationship between psychological capital and adaptive behavior. Based on these theoretical implications, we suggest managerial implications, research limitations, and future research.
New phosphate vanadates Ba2.4Mn2.6V1.5P2.5O15 and Ba2.6Mn2.4VP3O15
Authors: Zhuravlev V.D. , Tyutyunnik A.P. , Chufarov A.Yu. , Patrusheva Т.А.
Published: December 2022

The new phosphate vanadates, narrow range solid solutions Ba2.4Mn2.6V1.5P2.5O15 and Ba2.6Mn2.4VP3O15 were synthesized. The structural refinement based on X-ray powder diffraction data showed that these phosphate vanadates are characterized by monoclinic symmetry with space group P21/c, (# 14), Z = 4. The crystal structure of the studied solid solutions can be considered as a monoclinic distortion of the orthorhombic crystal lattice of Sr2.4-хCo2.6+xP3VO15. A rather rare phenomenon was found when barium and manganese (2+) cations share an octahedral site coordinated by oxygen ions.
Environmental and technical feasibility of a waste foundry sand applied to pavement granular layers
Authors: Morais Manuella , Levandoski William , Reis Joice , Rosa Francisco , Korf Eduardo
Published: December 2022

The foundry industry generates large amounts of residual byproducts, such as waste foundry sand (WFS). This high generation has motivated studies concerning the disposition of WFS, which in turn can be used for road subbases. Nevertheless, paving applications are still limited, especially regarding the behavior of WFS when added to a mixture of crushed materials. Hence, the objective of this study was to evaluate WFS reuse in mixtures with crushed materials, applied as granular layers of granulometric stabilized pavements. The crushed materials and WFS were characterized by size distribution, physical aspects, and different mixtures, and later submitted to mechanical testing. Initial tests were utilized to define mixtures (crushed material + WFS) that fulfilled the technical requirements for road subbases. California bearing ratio and resilient modulus tests indicated that WFS additions up to 12% for “A” grading improved the bearing capacity of the mixture; while in “E” grading, WFS additions up to 38% resulted in no expressive improvement in bearing characteristics. Thus, for both gradings, a structure with high density, strength, and low susceptibility to deformations can be used for road subbase construction without technical issues. Finally, the highest WFS content (38%) mixture was environmentally classified as a Class II A non-inert waste, indicating its environmental viability for road applications.
Determinantes en la Contratación de Trabajadores para las Empresas Manufactureras Ecuatorianas
Authors: Vargas-Bravo Karen Paulina , Córdova-Coronel Paula Andrea , Tonon-Ordóñez Luis Bernardo
Published: December 2022

Esta investigación tuvo como finalidad realizar un análisis sobre la cantidad de empleados contratados en el sector manufacturero ecuatoriano durante el periodo 2010-2019, dado que es uno de los tres sectores con mayor capacidad para generar plazas de trabajo. Sin embargo, en los últimos años ha presentado un menor dinamismo. Los datos proporcionados por la Superintendencia de Compañías, Valores y Seguros permitieron establecer variables logarítmicas de la masa salarial, ventas como variable proxy de la producción y activo fijo neto como variable proxy de la Formación Bruta de Capital Fijo (FBKF). Mediante datos de panel se estimó un modelo de efectos fijos por el método de mínimos cuadrados ordinarios. Los resultados mostraron que ante un incremento del 1 % en las ventas, ceteris paribus, la cantidad de trabajadores contratados se incrementó en un 0.22 %. Además, la variable ventas fue aquella variable que más influyó en la contratación de personal. También se pudo evidenciar que, ante una variación de la masa salarial del 1 %, ceteris paribus, las contrataciones variaron en 0.33 %. Finalmente, un cambio del 1 % en la variable activo fijo neto, ceteris paribus, provocó una variación del 0.003 % en la cantidad de empleados. Sin embargo, no fue una variable significativa individualmente.
La Gestión de la Producción a partir de Modelos Inteligentes para la Industria 4.0: Retos y Oportunidades
Authors: Ruiz-de la Peña Jenny , Pérez-Campdesuñer Reyner , Andrade-Molina Pablo Gustavo
Published: December 2022

En la década pasada el término Industria 4.0 ha recibido cada vez más atención, tanto en la industria como en la academia. La industria manufacturera ha evolucionado gracias a la revolución digital con el uso de dispositivos inteligentes para sistemas de información de fabricación inteligentes. Trabajar con sistemas de producción inteligente en la Industria 4.0 es una tarea compleja que requiere formas innovadoras para el desarrollo de los sistemas. Una forma de manejar la complejidad es el uso de técnicas de ingeniería dirigida por modelos inteligentes. Aunque los enfoques basados ​​en modelos tienen varias ventajas y pueden usarse para reducir la complejidad, los estudios para respaldar la Industria 4.0 aún son limitados. Este artículo utiliza el método bibliométrico para analizar el desempeño científico de artículos, países, autores y revistas en función del número de citas y redes de cooperación. La mayoría de los artículos se publicaron en congresos. Las palabras clave Industria 4.0 e ingeniería dirigida por modelos y sistemas integrados fueron las más utilizadas y representan las principales áreas de investigación. La mayor parte de la investigación relacionada con el campo se llevó a cabo en Austria y Alemania. Este estudio presenta la evolución de la literatura científica en la Industria 4.0 y los enfoques basados ​​en modelos inteligentes, también identifica áreas de interés de investigación actual.
Hillah Hukmi dalam Pengembangan (Legal Reform) Fatwa DSN MUI Tentang Pelaksanaan PPR Inden Syariah
Authors: Muttaqin Azhar
Published: December 2022

This article discusses Hillah Hukmi in the context of developing the Fatwa of DSN-MUI regarding the implementation of the Sharia Inden PPR. The focus of the study is on analyzing indications of the use of hillah hukmi in the way the DSN-MUI stipulates a law. Especially in fatwa 101/DSN-MUI/X/2016 regarding the al-Ijaarah al-Maushuufah Fii al-Dzimmah contract or commonly abbreviated as IMFD. The research method used is qualitative by conducting content analysis which is commonly used in library research models with a normative juridical approach. This article finds that in the development of the fatwa of DSN-MUI in order to support the development of Islamic financial institutions, it is indicated to use the concept of hillah hukmi. This can be seen when the implementation of the Indent PPR Sharia is allowed using the Ijaarah al-Maushuufah Fii Dzimmah (IMFD) contract. DSN-MUI issued the fatwa because it was considered an alternative that could solve the problem of Indent PPR which was often hampered, and also became a complementary contract to the Musyaraakah Mutanaaqishah (MMQ) and Ijaarah Muntahiyah Bi Tamliik (IMBT) contracts. IMFD is indicated to contain hillah because the terms and substance of the contract are different. Namely, making the lease contract as the basis for allowing home ownership even though the essence of the contract is the sale and purchase of greetings. Qualitatively, this article reveals how the legal development carried out by the DSN-MUI in this way, especially in order to respond to public demands for the issuance of a fatwa that is able to accommodate the need for ownership of indent houses based on sharia principles.
Patofisiologi dan Tatalaksana Sindrom Ekstrapiramidal
Authors: Ramsi Rahma Khairani , Zulaikha Afrina
Published: December 2022

Sindrom ekstrapiramidal adalah salah satu efek samping yang sering ditimbulkan akibat penggunaan antipsikotik. Insidensi sindrom ekstrapiramidal lima kali lebih beresiko terjadi pada penggunaan antipsikotik tipikal dibandingkan atipikal. Gejalanya berupa distonia akut, parkinsonisme, akathisia dan diskinesia tardif. Kondisi ini perlu diperhatikan karena dapat mengakibatkan ketidakpatuhan untuk minum obat secara rutin yang berakibat pada frekuensi kekambuhan menjadi meningkat. Penelitian di Malang pada tahun 2019 menunjukkan 53,12% pasien skizofrenia mengalami ketidakpatuhan dalam mengkonsumsi obat karena adanya efek samping yang membuat pasien tidak nyaman. Tatalaksana yang tepat perlu diberikan untuk mencegah terjadinya sindrom ekstapiramidal akibat penggunaan antipsikotik.
JOB INFLUENCE ON PRACTICE OF EXCLUSIVE BREASTFEEDING AMONG WORKING CLASS MOTHERS IN URBAN COMMUNITIES OF EKITI STATE, SOUTHWESTERN, NIGERIA
Authors: Babalola Serifat Asabi , Ajewole Ifedayo Charles , Babalola Waheed Olaide , Ogunsile Seyi Elizabeth
Published: December 2022

Breastfeeding is the first fundamental right of the child. Exclusive breastfeeding means giving a baby no other food or drink, not even water, in addition to breastfeeding Piyush (2007). In other to maintain the economic status and boost family income, women started to work in different sectors, which make it difficult for them to practice exclusive breastfeeding.The study descriptive cross sectional study design, the populations studied were the working-class nursing mothers attending the infant welfare clinics of urban communities in Ekiti- state. The study instruments were structured questionnaire. The data collected were analyzed and presented using tables and chart. The results revealed that acceptability of exclusive breastfeeding concepts is high among the population studied. It was discovered that majority of the respondents {99%} agreed and strongly agreed that exclusive breast feeding is desirable, feasible, nutritious and helps in child growth and development. Above half of the respondents {55%} agreed that working hours is a barrier to breastfeeding. The study revealed that majority of the respondents {90%} agreed to the fact that working class nursing mothers need flexible working hours for effective practice of exclusive breastfeeding. The study concluded that breastfeeding is desirable and feasible, and that government should increase maternity leave to six months after delivery for effective practice of exclusive breastfeeding.
Morphological, physiological, cytological characteristics and agricultural potential of colchicine induced autotetraploid plants in safflower
Authors: BAYDAR Hasan , TUĞLU Ümmü
Published: December 2022

Safflower (Carthamus tinctorius L.) is one of the important oilseed and bio-energy crops. All of the safflower cultivars in the world have diploid genomes (2n= 2x= 24). In this research, autotetraploidy induction in safflower was performed by colchicine treatments to the emerging shoot tips at the cotyledonary stage. As a result of flow cytometric analyses performed in the C2 progenies, autotetraploids (4x= 48) had DNA content of 4.88 pg 2C-1, while diploids (2x= 24) had 2.29 pg 2C-1. The autotetraploids in C2 generation exhibited bigger stomata size (33.40 μm to 46.90 μm in length) and a higher chloroplast number (9.5 to 17.2 in the guard cells), but less stomatal density (17.98% to 16.67% in index) compared to their diploid counterparts. However, autotetraploidy reduced the pollen viability from 80.24% to 16.20%, and seed set rate from 35.06% to 7.01% per capitula. As a result, autotetraploid plants were able to produce very few seeds despite the high unit seed size and weight in their heads. While oil content of the large-seeded autotetraploids was significantly lower, by two-fold, (26.37% to 13.23% in the whole seeds) than the small-seeded diploids, fatty acid composition was not significantly influenced by autopolyploidization.
Manifesting Justice: Wrongly Convicted Women Reclaim Their Rights
Authors: Medwed (Valena Beety) Daniel
Published: December 2022

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NATO Üyelerinin %2’lik Savunma Harcama Hedefine Yakınsamasının Sınanması
Authors: ÖNDER Hüseyin
Published: December 2022

Soğuk savaş sonrası dönemde, varlığı tartışmalara konu olan NATO’ya olan ilgi, Rusya’nın son dönemdeki Gürcistan ve Ukrayna savaşları ile yeniden artmıştır. Yeni üye katılımlarının söz konusu olduğu bu dönemde, NATO’nun yetenekleri ve üye ülkelerin askeri harcamaları da tartışmaların ilgi odağını oluşturmaktadır. Kurulduğu günden bu yana özellikle Avrupalı üye ülkelerin askeri harcamaları, sürekli ABD tarafından eleştirilmektedir. 2014 Galler Zirvesi ile resmi bir hedef olarak ortaya konan %2’lik askeri harcama hedefi ile bu tartışmalar yeni bir noktaya ulaşmıştır. Üye ülkelerin GSYİH’nın %2’si kadar askeri harcama yapmasını öngören bu hedefe, acaba üye ülkelerin yakınsaması söz konusu mudur? Bu sorunun cevabını verebilmek için 2015-2021 yıllarına ilişkin veriler ile Stokastik Yakınsama Analizi gerçekleştirilmiştir. Elde edilen bulgular 2021 yılında askeri harcama hedefini sağlayan ülkelerin dışında, İtalya, Norveç, Çekya, Bulgaristan, Hollanda, Danimarka, İspanya, Macaristan, Almanya ve Arnavutluk’ta %2’lik askeri harcama hedefine yakınsamaktadırlar. 2021 yılında %2’lik hedefin üzerinde yer alan ve analiz dışında kalan 10 ülke hesaba katıldığında, hedefi yakalayamayan ülkelerin %50’si, %2’lik hedefe yakınsamaktadırlar. Fakat son yıllardaki Rusya faktörüne rağmen NATO üyesi ülkelerin tamamında %2’lik hedefi yakalama gibi bir işaret olmaması da düşündürücüdür.
Covid 19 Pandemisinin Bankaların Finansal Performansı Üzerindeki Etkisi: Karşılaştırmalı Bir Analiz
Authors: GÜLCEMAL Tuba , DOĞAN Mesut
Published: December 2022

Bu çalışmanın amacı COVID-19 pandemisinin bankaların finansal performansı üzerindeki etkisini tespit etmektir. Araştırmada bankalara ait veriler, COVID-19 öncesi dönem ve COVID-19 dönemi olarak iki gruba ayrılmıştır. Böylelikle COVID-19 öncesi dönem ile COVID-19 dönemi açısından bankaların 9 çeyreklik dönemi kapsayan finansal oranları karşılaştırılmıştır. Araştırmada BIST Bankacılık endeksinde yer alan 8 adet mevduat bankasının verilerinden yararlanılmıştır. Çalışmada bankalar toplam 13 değişken ve sermaye yeterlilik, aktif kalitesi, yabancı para net pozisyonu, gelir gider yapısı, piyasa performansı, karlılık olmak üzere 6 kategoride incelenmiştir. Ampirik analizlerde bağımlı iki grup açısından karşılaştırma yapabilmek için eşleştirilmiş t-testi kullanılmıştır. Yapılan analizler sonucunda COVID 19 döneminde bankaların sermaye yeterlilik, aktif kalitesi, yabancı para net pozisyonu, gelir gider yapısı oranlarının etkilendiği tespit edilmiştir. Ayrıca COVID 19 döneminde COVID 19 öncesine göre bankaların karlılıklarında önemli bir değişiklik olmamasına rağmen piyasa performanslarında istatistiksel açıdan anlamlı bir yükseliş olduğu belirlenmiştir.