bluuebunny/crossref_metadata_2025 huggingface dataset:
Disadvantages of sowing methods on soil water content root distribution and yield of wheat (Triticum aestivum L.) in the Loess Plateau of South Shanxi, China
Authors: Noor Hafeez , Min Sun , Bin Lei , Gao Zhi-Qiang
Published: October 2022

Wheat (Triticum aestivum L.) is a staple crop worldwide and yield improvement since the green revolution was attributed to chemical nitrogen (N) fertilizer application. The field experiment was performed from 2016 to 2020 in the eastern part of Loess Plateau, China, to study the effect of two sowing practices carried out before summer fallow, i.e., wide-space sowing (WS) and drill sowing (DS). The results indicated the soil water content, root length surface density (RLSD), at anthesis by drought was 44% under WS and 29% with DS, while the reduction in above-ground dry weight was 67% under WS and 56% under DS. More soil water was depleted from the deep soil layer (80–100 cm depth) than that in the shallow layer (20–60 cm depth). The average contribution rates of soil water content at sowing to grain yield under DS were 23–25%. Thus, drill sowing in summer fallow should be adopted for high water storage and yield stability.
Phosphate adsorption improvement using a novel adsorbent by CaFe/LDH supported onto CO2 activated biochar
Authors: Missau Juliano , Rodrigues Marco Antonio S. , Bertuol Daniel Assumpção , Tanabe Eduardo Hiromitsu
Published: October 2022

It is imperative to remove phosphate from the aquatic system. This nutrient in excess can cause environmental problems such as eutrophication. Therefore, aiming to enhance phosphate removal, this work presents a novel adsorbent developed from the construction of Ca2+/Fe3+ layer double hydroxides (CaFe/LDH) supported onto biochar physically activated with CO2 [CaFe/biochar (CO2)]. Pristine biochar was produced from the pyrolysis of Eucalyptus saligna sawdust, activated with CO2, and then impregnated with CaFe/LDH. The CaFe/biochar (CO2) was characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and Brunauer–Emmett–Teller (BET). The characterization confirmed a proper synthesis of the new adsorbent. Experiments were conducted in the form of batch adsorption. Results indicated that the optimum pH and adsorbent dosage were 2.15 and 0.92 g L−1, respectively. Adsorption kinetics, isotherms, and thermodynamics were also evaluated. Adsorption kinetics and isotherms were better fitted by the pseudo n order and Freundlich models, respectively. Results also indicated a better adsorption capacity (99.55 mg·g−1) at 55 °C. The thermodynamic indicators depicted that the adsorption process was favorable, spontaneous, and endothermic. Overall, CaFe/biochar (CO2) could be potentially applied for the adsorptive removal of phosphate from an aqueous solution.
Working in group in project activity at English lessons in senior forms at MOBUG 2 named after I.S. Kolesnikov the town of Novokubansk
Authors: Iagodiak Iuliia Leovna
Published: October 2022

The article generalises group work in class project developing, refers to works of outstanding soviet psychologists and teachers dealing with personal activity of a student as the key to his achievements. The author describes effective forms of pair and group work in developing projects.
Cultural identity and self-determination of a person on the example of the memory of a stone
Authors: Masliakova Anna Ivanovna
Published: October 2022

This research aimed to analyze rocks from a culturological point of view. Author comes to the conclusion that attention to the environments affect cultural identity and improves self-esteem.
Approaches to the Creation of a Comprehensive Typology for the Monitoring System of Socio-Economic Development of Municipalities of the Russian Federation
Authors: Babkin R. A.
Published: October 2022

The article proposes approaches to the typologization of municipalities of the Russian Federation on the basis of objective indicators in the framework of one of the urgent tasks of the state policy of spatial development on the introduction of a system for monitoring socio-economic development at the municipal level. The analysis of many parameters of socio-economic development of municipalities allowed us to identify 9 most acceptable typologies for the development of this kind: specialization of the economy, socio-economic risks, geo-economic situation, agglomeration situation, population, urbanization, status and settlement role, climatic conditions, area. In the article in the case of regions located in different parts of the country: Kursk, Kaliningrad and Irkutsk regions. In the article shows that the selected indicators reflect various aspects of the economic, social and geographical location of the municipality and allow us to develop a stable typology of municipalities taking into account differences in their level of economic development, demographic potential and geographical location features and can be presented in the form of matrices with letter encodings. The obtained typological matrices in the future, depending on the combination of letter encodings, will become the basis for a comprehensive typology of municipalities.
Analysis of Unsatisfactory Consequences of Erysipelas Treatment
Authors: Shapoval Serhii , Vasylevska Larysa
Published: October 2022

Goal.  Find out the cause of unsatisfactory treatment outcomes in patients with destructive forms of erysipelas in the general population.

Materials and methods. Retrospectively and prospectively analyzed 284 case histories of patients who were hospitalized in the center of purulent - septic surgery KNP "City Hospital G3" Zaporozhye for the period 2016-2022.

Results. It was found that most often the local focus was localized on the upper and lower extremities. The most common clinical manifestations of intoxication in bullous and phlegmonous forms of erysipelas were: general weakness, hyperthermia, muscle pain. In the necrotic form of erysipelas, patients showed signs of severe intoxication with nausea, vomiting and confusion. In the complex treatment of patients with erysipelas, the main place belongs to the early surgical treatment of the area of ​​the pathological process and antibiotic therapy (ABT). Determination of serum procalcitonin allows to assess the progression and generalization of the process and is a sensitive test for the effectiveness of treatment.

Conclusions. Radical surgery and timely targeted ABT are key elements of success in the treatment of surgical forms of erysipelas and are not subject to revision. The main causes of unsatisfactory consequences in patients with erysipelas are: aggravation of the disease at the time of hospitalization by septic shock and multiple organ failure, severe decompensated comorbidities. Procalcitonin is a diagnostic marker that can predict the development of sepsis.

Key words: erysipelas, unsatisfactory treatment consequences, procalcitonin.
Nearest and Long-Term Results of Surgical Treatment of Acute Varicothrombophlebitis
Authors: Hadzheha Ivan
Published: October 2022

Introduction. Acute varicothrombophlebitis is one of the most common and dangerous complications of varicose veins of the lower extremities, as it is a common cause of deep vein thrombosis and pulmonary embolism. It develops in 30-60% of patients with varicose veins.

Methods. The evaluation of early and long-term results of surgical treatment of acute varicothrombophlebitis in 234 patients with acute varicothrombophlebitis in the basin of the great saphenous vein was performed.

Results. Depending on the prevalence of thrombotic process in the basin of the great saphenous vein, patients were divided into the following groups: Group I – inflow varicothrombophlebitis (n = 23 (9.8%); Group II – varicothrombophlebitis of the shin (n = 51 (21.8%); Group III – varicothrombophlebitis of the thigh (n = 21 (9.0%); Group IV – total varicothrombophlebitis (n = 27 (11.6%); Group V – ascending varicothrombophlebitis (n = 67 (28.6%); VI group – transfascial thrombosis (n = 45 (19.2%).

Conclusions. Surgical treatment of acute varicothrombophlebitis of the lower extremities according to the cumulative analysis allowed to achieve a positive treatment result in 94.5% of patients. Recurrence of thrombosis in the early and distant postoperative period was observed in 0.5% and 2.2%, respectively.
The Role of Adrenoreceptors and Calcium Ions in the Pathogenesis of Endocardium Endothelium Damage of Rats Under Stress Action on the Background of Hypercholesterolemia
Authors: Luchko Ihor , Huranych Tetyana , Dubkovetska Iryna , Storozhuk Leonid
Published: October 2022

Abstract. Topicality. Endothelial dysfunction is a key link in the pathogenesis, formation and progression of clinical manifestations of a significant number of cardiovascular system diseases. Some pathogenetic links and structures associated with morphofunctional disorders of cardiac endothelial cells under the stress conditions and its combination with hypercholesterolemia need further examination.

The aim of the study was to investigate the role of adrenoreceptors and calcium ions (by using of adrenoreceptors and Ca2+-channels blockers) in the pathogenesis of endocardium endothelium damage (by the content of free fatty acids in it and the number of exfoliated cells) as a result of emotional and pain stress action and its influence on the background of hypercholesterolemia.

Materials and methods of research. An electro-pulse model was used for stress reproduction. The alimentary hypercholesterolemia was simulated by keeping animals on an atherogenic diet during 2 months. To establish the role of the above-mentioned cellular structures in the mechanisms of endothelial cell damage, the following pharmacological drugs were administered to animals: β-adrenoblocker, α-adrenoblocker and Ca2+-channel blocker. The endocardium endothelium state was studied by using light microscopy, by analyzing the smears-imprints from macropreparations of ventricles by counting the number of endothelial cells in them. The content of free fatty acids was determined by radiochemical method.

Research results. It has been shown that β-adrenoblocker and Ca2+-channel blocker significantly limit the damage of endocardium endothelium of left ventricle under the action of emotional and pain stress, and to a much lesser extent, the same effect has α-adrenoblocker. The protective effect of mentioned preparations under the action of stressor factor against the background of alimentary hypercholesterolemia significantly decreases.

Conclusions. The obtained data, their analysis and comparison with the results of other experimental and clinical studies allow to make certain conclusions about the pathogenesis of endothelial dysfunction under emotional stress, as well as under conditions of its combination with hypercholesterolemia. In particular, an important link in the development of structural and some biochemical changes of endocardial endothelial cells is the toxic effect of catecholamines, which affect the organism’s functional systems mainly by β-adrenoreceptors (involving Ca2+ ions), to a lesser extent – by α-adrenoreceptors.

Key words: endocardium, stress, hypercholesterolemia, adrenoreceptors, calcium.
The Development of a UK Culturally Adapted Version of the Person Attuned Musical Interactions Manual: Protocol for a 2-Phase Mixed Methods Study (Preprint)
Authors: Waters Bryony , Orrell Martin , McDermott Orii
Published: October 2022

BACKGROUND

Previous research has suggested that care home interactions need significant improvements, especially those between staff and residents with dementia. Reasons for the lack of interactions are staff time pressures and residents’ language impairments. Although residents may experience reduced language abilities, they can continue to communicate through other forms, including nonverbal communication and music. Person Attuned Musical Interactions (PAMI) is a staff training tool that provides staff with music therapy skill-sharing to promote high-quality interactions between staff and residents using nonverbal communication and music. The tool was originally developed in Denmark. To ensure that the tool is appropriate for UK care homes, a team of researchers in the United Kingdom have culturally adapted the tool.

OBJECTIVE

This study aims to investigate the appropriateness of the adapted UK manual for UK care homes and to explore the impact of PAMI on residents with dementia and care staff.

METHODS

The project consists of 2 phases, a qualitative field-testing study and a mixed methods evaluation study, which have been developed following the Medical Research Council’s guidelines for complex interventions. Care staff and residents with dementia will be recruited from care homes in Lincolnshire, where the care staff will be trained in the PAMI intervention before implementing the intervention in their daily routines. Fortnightly reflective sessions will be provided throughout the phases to provide supervision and monitoring. The qualitative methods include interviews, reflective session transcripts, diary entries, and resident experience questionnaires. The quantitative outcome measures are residents’ music engagement, staff’s dementia competence, residents’ quality of life, and staff burden. The resident’s music engagement will be administered at 9 fortnightly time points. Staff’s dementia competence, resident’s quality of life, and staff burden will be administered at preintervention and postintervention time points.

RESULTS

The study has been funded by The Music Therapy Charity as part of a PhD studentship. The study began recruiting in September 2021. The research team aims to publish the results of the first phase in July to September 2023 and those of the second phase in October to December 2023.

CONCLUSIONS

This study will be the first to investigate the culturally adapted UK PAMI. Therefore, it will provide feedback on the appropriateness of the manual for UK care homes. The PAMI intervention has the potential to offer high-quality music intervention training to a larger population of care homes who may currently be restricted by finances, the availability of time, and a lack of training opportunities.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/43408
ORIGINAL RESEARCH ARTICLE: HISTOPATHOLOGICAL EVALUATION OF ENDOMETRIAL BIOPSIES IN WOMEN WITH GYNECOLOGICAL COMPLAINTS
Authors: BHUVA KAUSHIK , VACHHANI ANAND , SAVJIANI NISARG
Published: October 2022

Objectives: The objectives of the study were to study histopathological evaluation of endometrial biopsies in women with gynecological complaints.
Methods: The present study included 100 patients who attended gynecology department of Dhiraj General Hospital, SBKS MI and RC with the complaints of abnormal uterine bleeding. Endometrial biopsy or curettage done by clinician as part of diagnosis and management. Samples sent to the department of pathology for histopathological evaluation. Tissue after appropriate fixation and processing was embedded in paraffin block. After that, 4 micron tissue sections were cut and they were stained with H and E stain. The sections were evaluated on microscopy and an appropriate histopathological diagnosis was made.
Results: Out of 100 cases studied, 37% were found out to be secretory endometrium, 20% proliferative endometrium, 6% disordered endometrial glands, 3% simple hyperplasia without atypia, 5% complex hyperplasia without atypia, 1% endometrial hyperplasia with atypia, 2% endometrial polyp, 7% chronic nonspecific endometritis, 1% tuberculous endometritis, 3% Arias-Stella reaction, 6% products of conception, 3% deciduitis, 1% complete hydatidiform mole, 2% endometrial carcinoma, and 3% squamous cell carcinoma of cervix.
Conclusion: Abnormal uterine bleeding is a leading cause of morbidity in patients with gynecological complaints. It not just impairing health but psychologically also affects the patients. Endometrial biopsy is a safe, reliable, and less time-consuming outpatient procedure which can be used as an initial diagnostic tool in the patients with abnormal uterine bleeding.
ASSESSMENT OF MAGNESIUM (MG) AND ZINC (ZN) IN CARCINOMA BREAST PATIENTS
Authors: SONGARA NEERAJ SINGH , BHARGAVA AJAY KUMAR , CHAUDHARY AKSHITA , SHARMA ANUSHREE
Published: October 2022

Objectives: The objectives of the study were to determine and compare serum magnesium (Mg) and zinc (Zn) concentrations between breast carcinoma patients and healthy controls.
Methods: Determination and comparison of serum Mg and Zn was done between 50 breast carcinoma patients and 50 healthy controls. Determination and comparison of LFT in between 50 breast cancer patient during different course of chemotherapy. Trace element analysis was done using atomic absorption spectrophotometry. Statistical comparison was done, results were expressed as Mean±SD, p<0.05 was considered to be statistically significant.
Results: All groups were statistically matched in age, sex, and p>0.05. Serum Mg concentrations in cases and controls (0.9920±0.38 mg/dL) and (1.49±0.58 mg/dL) respectively, p≤0.0001* serum Zn concentrations in cases and controls were (66.74±12.58 μg/dL) and (90.88±14.51 μg/dL), respectively, p≤0.0001*.
Conclusion: Both serum (Zn) and (Mg) showed significant decreases in breast carcinoma patients as compare to healthy controls.
PHYTOCHEMICAL SCREENING WITH LC-HRMS PROFILING AND IN VITRO BIOLOGICAL ACTIVITIES OF ARGYREIA CUNEATA (L.) AND ARGYREIA SETOSA (L.).
Authors: Kale Sandip , Kirdat Pranoti , Kale Suresh , Dandge Padma
Published: October 2022

Objective: The present study was designed for phytochemical screening and biological activities of Argyreia cuneata (L.) and Argyreia setosa (L.) medicinal plants.
Methods: The mature leaves of A. cuneata (L.) and A. setosa (L.) were extracted with methanol (Ac-Me, As-Me) and ethyl acetate (Ac-EA, As-EA) solvent followed by qualitative and quantitative phytochemical analysis. Antimicrobial activity was evaluated by agar well diffusion method, whereas the activities such as antioxidant, antidiabetic, and anti-inflammatory were determined by in vitro methods. Liquid chromatography-high-resolution mass spectroscopy (LC-HRMS) was used to recognize the bioactive components.
Results: The highest phenolic content (0.840±0.130 mg GAE/ml extract) reported from As-Me and for flavonoids 0.128±0.012 mg QE/ml from Ac- EA. The Ac-Me exhibited higher inhibition zone against all the bacteria used for study. In antioxidant activity, Ac-Me and Ac-EA report highest 2,2 dipheny l,1 picryl hydrazine (IC50=0.580±0.012 mg/ml) and nitric oxide radical scavenging potential (IC50=0.772±0.059 mg/ml), respectively. For antidiabetic activity, As-Me showed highest α-amylase inhibition activity as well as glucose adsorption. In anti-inflammatory activity, Ac-EA exhibits highest (IC50=0.529±0.009 mg/ml) protein denaturation inhibition and Ac-Me showed highest (91.56±1.96%) HRBC hemolysis inhibition. The LC-HRMS analysis of methanolic extract reports the majority of phenolic compounds.
Conclusion: The study showed that the plants A. cuneata (L.) and A. setosa (L.) are well exploited and can be used for the source of potent natural bioactive components. This study also may thereby provide an insight in screening of crude drug.
FUNCTIONAL OUTCOME OF TENNIS ELBOW (LATERAL EPICONDYLITIS) TREATED BY LOCAL INJECTION OF PLATELET RICH PLASMA
Authors: Jiwani Rahil , Mehta Satish , Kadam Abhijit
Published: October 2022

Objective: The aim of the study was to evaluate the efficacy of local injection of platelet rich plasma in management of patients with tennis elbow who failed to respond to conservative management.
Methods: This was a prospective and cohort study in which 80 patients with lateral epicondylitis (Tennis elbow) were included on the basis of a predefined inclusion and exclusion criteria. Demographic details were noted. Patients were treated by local injection of autologous platelet rich plasma. Patients were followed up for 6 months. Relief of pain as well as functional improvement was assessed by patient-rated tennis elbow evaluation (PRTEE) score. SSPS 21.0 software was used for statistical analysis and p<0.05 was taken as statistically significant.
Results: Out of 80 studied cases, there were 36 (45%) males and 44 (55%) females with a M: F ratio of 1:1.22. The mean age of male (42.77±9.95 years) as well as female (41.06±9.56 years) was found to be comparable. Nineteen (23.75%) patients were involved in plumbing, 16 (20%) patients were involved in activities that required forceful use of screwdrivers such as electric work, 8 (10%) patients were involved in gardening, and 7 (8.75%) patients were involved in production or laying of bricks. Twelve (15%) patients were professional tennis player. The mean PRTEE score was 74.24±9.74 at the time of presentation. There was significant reduction in PRTEE score during follow-up and at the time of last follow-up visit, PRTEE score was found to be 8.32±2.56.
Conclusion: Local injection of autologous platelet rich plasma is effective in managing patients of lateral epicondylitis (Tennis elbow) who fail to respond to conservative management.
ESTADO DA QUESTÃO SOBRE A FORMAÇÃO DE PROFESSORES DE GEOGRAFIA
Authors: De Felippe Rodrigues Elisângela , Da Silva Cousin Cláudia
Published: October 2022

O presente artigo discute o que se mostra nas pesquisas sobre a formação de professores de Geografia nos cursos de licenciatura. Para tanto, utilizou-se a metodologia do Estado da Questão (EQ) das autoras Nóbrega-Therrien e Silveira (2011). O EQ se respalda na pesquisa e no levantamento de bases de dados científicos, mediante a busca de uma gama variada de periódicos que aprofunde a discussão teórica e metodológica da pesquisa. Para Nóbrega-Therrien e Silveira (2011), o EQ pode conter a busca de palavras-chave, resumos, títulos de artigos, dissertações e teses relacionados ao tema investigado. As produções selecionadas para esta investigação tiveram como marco temporal o período compreendido entre 2008 e 2019. Os resultados apresentados foram que as pesquisas produzidas ao longo desse período se referem: às narrativas (auto)bibliográficas na Geografia-Licenciatura, à relação entre os cursos de Geografia – Licenciatura e as Escolas, à partilha das experiências nos lugares formativos docentes, à trama tecida entre a Educação Ambiental Crítica e Transformadora e a Geografia Crítica.
Performance y ciudadanía
Authors: Chamorro Andrea
Published: October 2022

In the northernmost parts of Chile, assimilation policies that defined indigenous populations as "foreign" and racially non-white characterized the construction of the Chilean nation-state. Despite discrimination and stigmatization, the Aymara people have maintained festive-ritual ties to their native territories in the Andes and modernized their festivals, ceremonies, dances, and music in urban settings. Considering the practices, views and emotions of the Aymara dancers and their descendants, I suggest that the performances at the Andean Carnival Inti Ch'amampi, Con La Fuerza del Sol in Arica –  a city in the Arica and Parinacota Region of Chile – embody the practices and experiences of a people that problematizes their historical alterity from the Chilean nation and the schema of social, historical and political representation imposed upon them under the logic of legal citizenship. As such, the performances are political strategies to intervene and dialogue with public space and position embodied memories and knowledge to outline a landscape that becomes multiple.
Design and Implementation of Sleep Aid System
Authors: Katyayan Ved
Published: October 2022

Abstract: Mental stress is a major issue in today’s competitive environment. Insomnia, memory issues, depression, and other disorders can all be caused by a lack of sleep. Frustration, irritation, and a higher risk of heart disease are all symptoms of stress. Anxiety, inability to concentrate, and car accidents etc. The majority of individuals only sleep for 3-4 hours each day, which is insufficient. Enough. People should sleep for roughly 6-7 hours every day in reality. To alleviate this problem, many people utilize high doses of drugs. This is an issue that is extremely detrimental to the humanbody. There are several options available. Therapy options for insomnia is also there. Yoursleep cycle is regulated by aninternal “body clock” that controls when you feel weary and ready for bed or refreshed and awake which is known as cardiac rhythm. The circadian rhythm is a 24-hour cycle that this clock follows. You will grow progressively fatigued during the day after waking up from sleep. These emotions will peak in the evening, just before bedtime. Adenosine, anorganic substance generated in the brain, linked to sleep drive, also known as sleep-wake homeostasis. As you get extra weary throughout the day, your adenosine levels rise, and your body subsequently breaks down this chemical while yousleep. The circadian rhythm is also influenced by light. The hypothalamus is a particular area of nerve cellsin the brain,and the suprachiasmatic nucleus is a cluster of cells in the hypothalamus that processes signals when the eyes are exposed to natural or artificial light. The brain uses these signals to decide whether it is day or night. As natural light fades in the evening, the body produces melatonin, a drowsiness-inducing hormone. The hormone cortisol, which increases energy and alertness, is released when the sun rises in the morning. Most individuals require at least seven hours of sleep each night in order to operate well cognitively and behaviorally. An inadequate quantity of sleep might have catastrophic consequences. Sleep deprivation has been linked to attention lapses, impaired cognition, delayed responses, and mood swings in certain studies.
Gut Microbiome and Human Health- A Brief Overview
Authors: B. E Ashraf Navab Moghal , K Manjunatha , B Nithin , A Sri Charan , J Usama Zaid , P Suman
Published: October 2022

Abstract: Humans have co-evolved with microorganisms, which play a pivotal role in determining the overall well-being of biological systems. Evolution has made certain species of bacteria thrive in the human gut, utilising the catabolized nutrients of the host and exhibiting symbiosis. It chiefly comprises a densely populated group of microbes, collectively called the Gut Microbiota. The relationship between the human system and the gut microbiome is a very sparsely introduced subject yet managed to catch everyone's eye, just for its sheer complexity. The nature and type of microbe present in the gut vary widely with respect to socio-economic, ethnic, and geographic influences. There has been extensive study done and some are underway showcasing the potential link between the gut-microbiome and the host, humans. As amusing as the gut-microbiome it is, its relationship with the host is quite remarkable. The gut-human connection is important in metabolism, coordination (brain axis), immunity, and, of course, disease. The diseases that were known earlier have recently been known to be associated with the gut microflora. Hence, this area of gut and human health has been in the focus of researchers and scientists in recent times. In this review literature, we have tried to consolidate the health aspects of humans influenced by gut dysbiosis. A few interactions are also discussed, like metabolic activity, gut-brain axis, drug action, diet influence, and immunity. This literature is aimed at showcasing the association and complexity of the gut microbiome with human health.
Criatividade em estudantes de Design: uma análise comparativa entre o início e final de curso
Authors: Pederiva Vanessa , Boff Raquel De Melo
Published: October 2022

O presente estudo objetivou investigar se há diferença significativa em criatividade figural entre estudantes de início e de final da Graduação em Design. Para tanto, seguiu-se a abordagem quantitativa e transversal, de comparação entre grupos. Participaram deste estudo 31 sujeitos, com idades entre 18 e 32 anos, dos quais 15 cursavam o primeiro ano, 14 estavam no último ano e dois eram recém-formados. Os instrumentos utilizados foram o Teste de Torrance – Pensando Criativamente com Figuras e uma ficha de dados sociodemográficos. Foi utilizado o teste Mann Whitney para amostras independentes, sendo considerado um intervalo de confiança de 95%. Evidenciou-se que, dos 15 indicadores de criatividade que o teste avalia, nove apresentaram diferença estatística significativa (p ≤ 0.05), permitindo supor que, neste estudo, o curso de Design pode auxiliar no desenvolvimento do potencial criativo dos estudantes.
Avaliações municipais no Ceará: características e usos dos resultados
Authors: Oliveira Ana Gardennya Linard Sírio , Costa Anderson Gonçalves , Vidal Eloisa Maia
Published: October 2022

O artigo descreve iniciativas de avaliações em municípios cearenses, a partir de survey enviado para as 184 Secretarias Municipais de Educação, com o intuito de identificar quantas, quais e de que forma funcionam. Os dados mostram que 64 municípios possuem algum tipo de avaliação municipal, o grau de institucionalização é variado e a maior quantidade data de 2017 em diante. A maioria avalia outras disciplinas e anos escolares, mas predomina a ênfase em Língua Portuguesa e Matemática e nos 2º, 5º e 9º anos do ensino fundamental. As avaliações têm periodicidade variável; são elaboradas pelas equipes municipais; os relatórios chegam às escolas de forma bastante detalhada e parte delas estão associadas à premiação e aos bônus. Elas amplificam e fortalecem a cultura de avaliação nos municípios, colocando-os em um contínuo estado de prontidão para algum tipo de avaliação externa.
Qada Zakat: Suatu Perbincangan Menurut Hukum Syarak
Authors: Syed Fadil Syed Muhammad , Daud Mohd Zaidi , Jamaludin Mohd Hafiz
Published: October 2022

According to Islamic law, Muslims who have complete the full period of an Islamic year (hawl) must pay zakah. It can, however, be found among Muslims who negligently fail to pay zakah within the stipulated period. Every obligatory practise must be performed within the time determined by Allah SWT in the discourse of fiqh. Hence, this article will look at the aspect of qada’ zakah in view of the shara‘ discussion. Thematic content analysis of themes based on the schools of thought will be used to thoroughly discuss this topic. In conclusion, Shariah allows and provides exemption to zakah payers in unavoidable situations. As a result, zakah should be paid even if it is not within the timescale provided if there is justification allowed by shara‘.
Ogilvie's syndrome after caesarean section - a dangerous misdiagnosis
Authors: Omran Kareem , Omran Osama , Shahin Maha
Published: October 2022

Ogilvie’s syndrome is a clinical condition that mimics all feature of
large bowel obstruction, but with no mechanical cause. If untreated, the
condition has a high mortality rate due to rupture and ischaemic
perforation of the bowel. We present a case of Ogilvie’s post-caesarean
section and emphasis the correct management.
Tomato chlorosis virus p22 interacts with NbBAG5 to inhibit autophagy and regulate virus infection
Authors: Shang Kaijie , Xiao Li , Zhang Xianping , Zang Lianyi , Zhao Dan , Wang Chenchen , Wang Xipan , Zhu Changxiang , Zhu Xiaoping
Published: October 2022

Tomato chlorosis virus (ToCV) is a member of the genus Crinivirus
in the family Closteroviridae. It has a wide host range and wide
distribution, causing serious harm to the vegetable industry. The
autophagy pathway plays an important role in plant resistance to virus
infection. Viruses and plant hosts coevolve in defence and antidefence
processes around autophagy. In this study, ToCV p22 protein was selected
to verify the interaction between ToCV p22 and NbBAG5. Through
overexpression and downregulation of NbBAG5, it was found that NbBAG5
could negatively regulate ToCV infection. NbBAG5 was found to be
localised in mitochondria and can change the original localisation of
ToCV p22, which is colocalised in mitochondria. Further study found that
NbBAG5 inhibited the expression of mitophagy-related genes and the
number of autophagosomes, thereby regulating viral infection by
affecting mitophagy. In summary, this study demonstrated that ToCV p22
affects autophagy by interacting with NbBAG5, established the
association between virus infection, BAG proteins family and autophagy
pathway and explained the molecular mechanism by which ToCV p22
interacts with NbBAG5 to inhibit autophagy to regulate viral infection.
Early dose of Adenosine, postRadiofrequency abLation of accessory pathwaY in determining acute procedural Success (EARLY Study)
Authors: Manickavasagam Anand , Guttikonda Siva Nageswara Rao , Bootla Dinakar , Patloori Sirish Chandra Srinath , Jain Ashish , Chase David , Selvaraj Raja , Jacob John
Published: October 2022

Introduction Post ablation of the accessory pathway (AP), the
patient is observed in the catheterization laboratory for a variable
period for resumption of pathway conduction. Aim of the study was to
determine whether the administration of intravenous adenosine at 10
minutes after ablation of accessory pathway (AP) would have the same
diagnostic accuracy as waiting for 30 minutes in predicting the
resumption of AP conduction. Methods: This was a prospective
interventional study conducted in two centers. Post ablation of the AP,
intravenous adenosine was administered at 10 minutes to look for dormant
pathway conduction. The response was recorded as positive (presence of
pathway conduction), negative (absence), or indeterminate (not able to
demonstrate AV and VA block and inability to ascertain AP conduction).
Results: The study included 110 procedures performed in 109
patients. Adenosine administration at 10 minutes showed positive result
in 3 cases (2.7%), negative result in 99 cases (90%) and indeterminate
result in 8 cases (7.3%). Reconnection of accessory pathway at 30
minutes post ablation was seen in 8 cases (7.3%). Of these 8 cases,
10minutes adenosine administration showed positive test in 3 patients
and negative test in 5 patients. Adenosine test at 10 minutes has a
sensitivity, specificity, positive predictive value, and negative
predictive value of 37.5%, 100%, 100% and 94.9% in identifying the
recurrence of accessory pathway conduction at 30 minutes, respectively.
Conclusion: Absence of pathway conduction on administration of
adenosine 10 minutes post ablation does not help predict the absence of
resumption of conduction thereafter.
An Approach of Coastal Areas Flood Dynamics Using GIS Techniques
Authors: Shehzadi Tabinda , Naeinm Jawaria
Published: October 2022

The exceptional conditions of the coast for the development of multiple human activities have led to a continuous migration of inhabitants, industries and services to the coastal areas. The reasons for such migration have evolved over time, being historically the commerce, the port activity and the agricultural settlements in the fertile deltas and alluvial plains the causes of such migration, while at present it is are tourism associated with leisure and the enjoyment of the coastline.
Electricity consumption and market prices in Serbia impact of the pandemic of COVID-19
Authors: Corovic Nebojsa , Gvozdenac-Urosevic Branka , Katic Nenad
Published: October 2022

The COVID-19 pandemic has begun in early 2020 and still continues to strongly
affect the entire world delivering a significant global, shock, but varying
across countries and commodity sectors. The Government of the Republic of
Serbia has been adopting different measures to slow down the dissemination
of the corona-virus, specifically nationwide lockdown in March and April
2020. Business activities have been reduced. The pandemic situation has
changed the lifestyle as people are mostly staying home and working from
home. This paper provides a re-view of unprecedented impacts of COVID-19
pandemic, with restrictions and lockdown in Serbia, on electricity sector at
this stage of the crisis. The outcomes offer a contribution to the body of
literature because limited research has been conducted on these
relationships in case of Serbia. Sets of statistical indicators are used to
analyze changes the electricity sector has been facing. Data visualization
is used to compare developments during the pandemic with those of previous
years. Our research and data-driven analysis of these impacts should
improve the understanding of the techno-economic effects of unforeseen
events, such as a pandemic, on the power system, scrutinizing if effects
could be relative-ly short?lived or longer?lasting.
Severe accident analysis of the dual-functional lithium-lead test blanket module using ISAA-DFLL code
Authors: Zhang Bin , Gao Peng-Cheng , XU Tao , Qian Rong-Rong , Jing Mao-Lin , Shan Jian-Qiang
Published: October 2022

The international thermonuclear experimental reactor (ITER) project aims to
build a tokamak fusion test reactor to verify the feasibility of fusion
reactors. The test blanket module (TBM) is the key component of the
international thermonuclear experimental reactor. The fusion design study
team proposed the concept of the dual-functional lithium-lead test blanket
module (DFLL-TBM). The integral severe accident analysis (ISAA) is a
self-developed ISAA code that models the progression of severe accidents in
nuclear power plants. A broad spectrum of severe accident phenomena
including fission product release and transport behavior is modeled in ISAA.
In this paper, a new version of ISAA, referred to as ISAA-DFLL is
introduced for the application of DFLL-TBM test blanket module into the
treatment of multi fluids and the modules of the new physical property and
heat transfer. The modification is verified by comparing the steady-state
temperature distribution of the DFLL-TBM first wall with the design
parameters. Then accident analysis of In-vessel loss of helium coolant in
first wall and TBM pipe is conducted by using the ISAA-DFLL code. By
comparing the calculation results with the general safety requirements for
TBM, it is concluded that the design of the DFLL-TBM system and the
modifications of the current version are reasonable and accurate.
Design of hybrid heat and power co-generation system
Authors: Jin Yingai , Lv Mingjie , Yan Yuying , Quan Mingyu
Published: October 2022

The energy revolution considering renewable power is indispensable and
inevitable in the development of modern power industry, yet has been
restricted by many practical problems. The instability of renewable energy
makes the whole power generation system unable to maintain stable output,
which causes fluctuations in the power grid system, and ultimately affects
the user side. Also, there are few researches on hybrid heat and power
co-generation system and when applied to the regional power supply, current
systems converse electric energy to thermal energy to meet the heating
demand of users, which reduces the energy quality. Hybrid two or more kinds
of renewable energy is a way to eliminate instability of renewable energy
power generation system. In this paper, a hybrid heat and power
co-generation system is designed to reach both heat and power demands of
users, a solar-geothermal power generation system was simulated on ASPEN
PLUS platform. The output power, entropy and energy efficiency are analyzed
to optimize the system. Based on the solar-geothermal power generation
system, exergy analysis shows that the parallel heating and power generating
system is much more efficient than the original system.
Experimental study on no heterogeneous reduction by char
Authors: Yu Shilin , Lv Zhaomin , Miao Yang , Xiong Xiaohe , Tan Houzhang
Published: October 2022

The NO heterogeneous reduction by char is one of the most prominent options
to control NOx emissions from coal-fired power plants. Experiments on the
char-NO heterogeneous reaction were carried out in an electrically heated
fixed-bed reac-tor to investigate the effect of temperature, type of char,
pretreatment method, additives and reaction atmosphere on the NO reduction
capacity of char. The re-sults showed that temperature plays a crucial role
in the NO reduction by differ-ent char. The kinetic analysis showed that
char-NO heterogeneous reaction is controlled by chemical kinetic below Tt
and by diffusion kinetic above Tt. The value of transition temperature Tt
depends on the types of char and ranges from 600?C to 800?C. The
synergistic effect of specific surface area, mineral abun-dance and
reactivity combine to result in the reduction efficiencies of different
char. Oxygen has a promoting effect on the char-NO heterogeneous reaction,
and the oxygen content of the promoting peak moves to low oxygen content
with in-creasing temperature. At 1050 ?C, the denitrification efficiency at
0.25% O2 con-tent is 12.7% higher than that under oxygen-free conditions. At
high tempera-tures, the promotion of the char-NO heterogeneous reaction by
CO and the inhi-bition of the reaction by CH4 were more obvious.
Early-Onset Type 2 Diabetes and Mood, Anxiety, and Stress-Related Disorders: A Genetically Informative Register-Based Cohort Study
Authors: Liu Shengxin , Leone Marica , Ludvigsson Jonas F. , Lichtenstein Paul , Gudbjörnsdottir Soffia , Landén Mikael , Bergen Sarah E. , Taylor Mark J. , Larsson Henrik , Kuja-Halkola Ralf , Butwicka Agnieszka
Published: October 2022

OBJECTIVE

To assess the association and familial coaggregation between early-onset type 2 diabetes (diagnosed before age 45 years) and mood, anxiety, and stress-related disorders and estimate the contribution of genetic and environmental factors to their co-occurrence.

RESEARCH DESIGN AND METHODS

This population-based cohort study included individuals born in Sweden during 1968–1998, from whom pairs of full siblings, half-siblings, and cousins were identified. Information on diagnoses of early-onset type 2 diabetes and mood (including unipolar depression and bipolar disorder), anxiety, and stress-related disorders was obtained from the National Patient Register. Logistic and Cox regression models were used to assess the phenotypic association and familial coaggregation between type 2 diabetes and psychiatric disorders. Quantitative genetic modeling was conducted in full and maternal half-sibling pairs to estimate the relative contributions of genetic and environmental factors to the association.

RESULTS

Among a total of 3,061,192 individuals, 7,896 (0.3%) were diagnosed with early-onset type 2 diabetes. These individuals had higher risks of any diagnosis (odds ratio [OR] 3.62 [95% CI 3.44, 3.80]) and specific diagnosis of unipolar depression (3.97 [3.75, 4.22]), bipolar disorder (4.17 [3.68, 4.73]), anxiety (3.76 [3.54, 3.99]), and stress-related disorders (3.35 [3.11, 3.61]). Relatives of individuals with early-onset type 2 diabetes also had higher overall risks of the examined psychiatric disorders (ORs 1.03–1.57). These associations are largely explained by genetic factors (51–78%), with the rest explained by nonshared environmental factors.

CONCLUSIONS

Our findings highlight the burden of mood, anxiety, and stress-related disorders in early-onset type 2 diabetes and demonstrate that shared familial liability may contribute to their co-occurrence, suggesting that in the future research investigators should aim to identify shared risk factors and ultimately refine preventive and intervention strategies.
Fatigue Properties of Weakened and Non-weakened Roots Restored with CAD-CAM Milled Fiber Post, Prefabricated Fiber Post, or Cast Metal Post
Authors: Oliveira GR , Machry RV , Cadore-Rodrigues AC , Sarkis-Onofre R , Valandro LF , Bacchi A , Pereira GKR , Spazzin AO
Published: October 2022

Statement of problem

Customized glass fiber posts using CAD-CAM technology have been suggested for restoring endodontically treated teeth. However, how weakened or non-weakened roots restored with anatomical CAD-CAM posts behave under cyclic fatigue is not clear.

Objective

To evaluate the load-bearing capacity under fatigue (fatigue failure load [FFL], the number of cycles for failure [CFF], and survival probabilities) and fracture pattern of weakened and non-weakened roots restored with CAD-CAM fiber post and cores, metal cast-post-core, and prefabricated fiber post and resin core.

Methods and Materials

A total of 60 crack-free bovine incisor roots (13 mm in length) with standard geometry were obtained and randomly allocated considering the factor “root condition” in two levels (weakened and non-weakened). Thus, half of the roots were weakened to obtain a wall thickness of 0.5 mm. After that, the endodontic treatment was executed, all roots embedded with acrylic resin and the specimens randomly allocated (n=10) considering the factor “post system” in three levels (CAD-CAM: CAD-CAM milled glass-fiber post and core; MBC: metallic-based post and core; and FRC: prefabricated glass-fiber post and composite resin core). The posts were luted with a dual-cure self-adhesive luting agent. Then, all teeth received a metallic crown. An initial load of 100 N at 20 Hz for 5000 cycles was applied for the step-stress fatigue test, followed by incremental steps of 50 N for 20,000 cycles each step, up to failure. A fracture pattern analysis was performed.

Results

CAD-CAM fiber post (FFL: 865 N; CFF: 311,000 cycles) presented similar fatigue performance (p>0.05) to FRC (FFL: 925 N; CFF: 335,000 cycles), with 100% of repairable fractures for non-weakened roots; however, both groups presented worse performance than MBC (p<0.05; FFL: 1265 N; CFF: 471,000 cycles) which led to 100% of catastrophic failures. No statistical difference was found in fatigue performance among the three systems for weakened roots (p>0.05; FFL: 1035-1170 N; CFF: 379,000-433,000 cycles), with a high rate of catastrophic failures.

Conclusions

CAD-CAM fiber post presented similar fatigue performance to MBC and FRC approaches when restoring weakened roots. CADCAM was similar to FRC when restoring non-weakened roots, while MBC enhanced fatigue properties in this scenario.
The nature of disasters and their challenges to healthcare ethics
Authors:   , Evans Jeffery
Published: October 2022

Disasters are exceptional events that cause damages on a scale that result in widespread unmet human needs that are critical and urgent. The exceptional circumstances in disasters may render established ethical norms of healthcare practice inapplicable or inappropriate. Healthcare professionals who work in disasters are faced with choices that have direct impacts on the life, death, and suffering of both disaster victims, and themselves. Some choices faced may be dilemmatic choices between competing irreconcilable moral principles. Whilst some choices reflect uncertainty as to how to realise moral precepts. In these situations, there is an appeal for guidance that is fitted to the circumstances found within disasters. Appealing to codes of professional conduct and ethics is problematic as many codes are either silent on the difficulties encountered in disasters, or overly demanding through the use of imperative language. Considering the relative weakness of published codes, universal principles of first do no harm and do good are offered as guiding principles. However, in disasters opportunities exist for harming through nondoing, creating the possibility that as aid is rendered to some, harm is occasioned to others. When considering doing good in disasters, maximising aggregate benefit is the established ethical framework employed. However, this framework’s foundational assumptions of aggregation of benefits and harms, commensurability of different ends, and the privileging of the greater number are open to critique. Thus, the principles of first do no harm and do good are problematic in disaster settings. Virtue ethics is proposed as a novel response to the difficulties faced by healthcare professionals in disasters. Virtue ethics provides an account of the healthcare professional as one who must choose with wisdom, courage and integrity in exceptional circumstances. Further, virtue ethics provides an understanding of how it is possible to act well in the tragic circumstances found within disasters.