bluuebunny/crossref_metadata_2025 huggingface dataset:
LIMITED FACE-TO-FACE LEARNING MANAGEMENT DURING THE COVID-19 PANDEMIC
Authors: Ainun Amaliya Paramita  , Farid Setiawan  , Retno Palupi  , Rijal Khoirul Anam
Published: January 2024

This study aims to understand the management of learning in schools at SD Negeri Caturtunggal 3, Depok, Sleman, Yogyakarta Special Region, during the Limited Face-to-Face Learning (PTMT) was carried out during the Covid-19 pandemic. The method used in this research is qualitative. The results showed that the limited face-to-face learning carried out after the previous learning was done online, there were several obstacles that the students strongly dominated at the beginning of the learning implementation. Limited face-to-face learning has obstacles. Namely, many students are confused when invited to icebreaking. Students are still adjusting to the learning, and the reality of student understanding seen from the assessment during online learning and then implemented in a limited manner is very different. Although at the beginning of the implementation of limited face-to-face learning, there were still obstacles, SD Negeri Caturtunggal 3 was able to prepare and develop sound strategies to manage limited face-to-face learning to anticipate unwanted things.
LEARNING MANAGEMENT SYSTEM AS COVID 19 RISK MITIGATION
Authors: Aliwafa Aliwafa , Muhammad Muhammad , Shofiya Shofiya
Published: January 2024

This study aims to analyze the learning management system as a risk mitigation for Covid 19 at an early childhood education institution in Probolinggo Regency. The research method used is a qualitative case study type. In order to get an overview of the Learning Management System Learning as Covid Risk Mitigation in early childhood, the researchers mingled directly in the implementation of learning and made observations and documented learning activities at the institution. Interviews were conducted with principals and teachers. The results of the study indicate that teacher innovation using a learning management system is carried out through; parental involvement, use of online media, selection of materials, assessment, and follow-up. This study implies that teachers must have innovation and creativity in managing their learning according to the targets they have set to generate total motivation and intelligence of students.
OBSTACLES HINDERING THE IMPLEMENTATION OF STRATEGIC PLANNING FROM SECONDARY SCHOOL PRINCIPALS IN KHARTOUM STATE
Authors: Bannaga Taha Al-Zubair  , El-Zain El-Khalefa El-khder
Published: January 2024

The study aimed at indemnifying the main obstacles that face the application strategic planning From Secondary School Principals in Khartoum State. For that purpose, the descriptive analytic method was used. The study population included all secondary school principals in Omdurman locality membrane 220. Out of the study population a random sample consisting of 120 principles was chosen. For the purpose of data collection, the researchers designed and used a questionnaire distributed to all sample members. To analyze the collected data, the statistical package (SPSS) was used. The main following results were reached: the school principals face difficulties in analyzed the point of the strength, weaken, opportunities, and threats facing their schools as they lack the basic scientific foundation and know ledge of strategic planning, The school principals encounter difficulties and problems when they handle and go about strategic planning of their schools due to the fact that they lack the basic required skills and competences regarding the implementation of the strategic planning processes. In view of the results being researched, it is recommended that: Obstacles that hinder the implementation of strategic planning need to be removed in order to active the school strategic planning processes.
HUBUNGAN PENILAIAN KINERJA DAN PENGEMBANGAN KARIER DENGAN MOTIVASI KERJA PARA KARYAWAN
Authors: Fathudin Ali
Published: January 2024

The purpose of this study is to determine the extent of the relationship between performance appraisal and career development with the work motivation of employees at the Al-Ikhlas Mosque Foundation (YMAI). The research used an experimental approach and inferential statistical analysis. The research population consisted of several YMAI employees randomly selected from each work unit, namely SD units, SMP units, KB/TK units, and Secretariat units. The result is Chi-Square = 0.05, df = n-1 95% confidence level. So that employee assessment positively affects employee performance and can be accepted. This is evident from the results of the t-test calculation; the t-test results state that the t-value for the employee development variable is 5.534, with a probability of 0.000. Using a significant level of 5%, the probability value is less than 0.05. This shows that H2 is accepted and H0 is rejected, so it can be concluded that the employee development variable has a positive and significant effect on employee performance.
STUDENT CREATIVITY PROGRAM AS A MEDIA TO BUILD THE ENTREPRENEURSHIP SOULS OF STUDENTS IN PONDOK PESANTREN
Authors: Himmah Mufidatul , Abdullah Abdullah , Navisa Maknunatun
Published: January 2024

This study aims to analyze the students' creativity program as a medium to build students' entrepreneurial spirit at the Nurul Jadid Islamic Boarding School. This research method uses a qualitative research method; the type of case study uses data collection techniques using observation, interview and documentation. The data analysis was carried out circularly, starting with data collection, data reduction, data presentation, and concluding. The results of the study indicate that Islamic boarding schools develop creative activities for students by providing places for activities to build an entrepreneurial spirit through pesantren extracurricular activities, managing used goods, applying in pesantren skills competitions, and skills activities in every institution under the auspices of the Nurul Islamic Boarding School.
THE EFFECT OF PRINCIPAL DISCIPLINE AND COMPENSATION ON TEACHER PERFORMANCE RESULTS IN MADRASAH
Authors: Laila Nur
Published: January 2024

This study aims to determine the significant effect of principal discipline and compensation on the performance results of all MTs teachers in Teluk Pandan District. This type of research is quantitative and associated with a population of 123 teachers, and the research sample is 94 teachers. The data collection technique uses a questionnaire. Simple and multiple linear regression analyses then analyzed the data. The results showed that the effect of principal discipline and compensation on teacher performance was 54.9%, while other factors influenced the remaining 45.1%. So it can be concluded that the better the principal's leadership and compensation, the higher the teacher's performance results.
TRANSFORMATION FROM THE EDGE; ORGANIZATIONAL CHANGE MANAGEMENT BASED ON ISLAMIC CULTURE IN PESANTREN
Authors: Romli Mustain , Syamweil Faizin
Published: January 2024

This study analyzes change management based on Islamic culture at the Nurul Jadid Islamic Boarding School. This study uses a qualitative case study type method. Data collection techniques using interviews, observation, and documentation. The results showed that the stages of change management carried out by Pesantren Nurul Jadid based on the perspective of Kurt Lewin, among others: first, at the Unfreezing stage (review or survey, particular direction from the leadership to subordinates), mapping the potential of each human resource, motivation). The second is the Changing stage (socialization, seminars, training). The third is the Refreezing stage (creating a new culture or condition, cooperation, commitment, and evaluation).
DIGITALIZATION OF ISLAMIC EDUCATION PLANNING IN MADRASAH
Authors: Prihastia Agnes , Hani Umi , Safi’i Maskun , Mausul Silmi , Daimah Daimah
Published: January 2024

The entry of Indonesia in the era of the industrial revolution 4.0 caused various changes in various sectors of life in society such as the order of life, systems, and various fields. In the field of education itself, of course, must follow the current developments in order to be effective because a child is born for his time and an education regulator must be able to adapt to the times. All of that of course must be accompanied by a careful planning so that in the future it can run effectively and efficiently. It is necessary to formulate a national policy strategy through awareness and maturity of thought. In addition, public education needs to be adapted to meet the needs of expertise in the industrial era 4.0. Educators, education staff, managers of Islamic educational institutions also need new management and have a hand in filling industry 4.0. President Joko Widodo called for the time and energy of madrasa principals and teachers not to be wasted on making accountability reports, but could focus more on developing the quality of learning. Therefore, in Indonesia, it is necessary to start managing education in new ways, such as the use of e-RKAM.
RECRUITMENT AND SELECTION: UNDERSTANDING THE SCHOOL'S STRATEGY IN REALIZING SUPERIOR EDUCATIONAL STAFF PERFORMANCE
Authors: Pujiono Pujiono , Yetri Yetri , Amiruddin Amiruddin
Published: January 2024

This study aims to analyze the strategy of recruitment and selection of teaching staff in order to achieve the goals of the institution. The method used in this study is a qualitative descriptive method, which describes existing phenomena. As for data collection techniques using observation, interviews and document study. Researchers conducted interviews with school principals, deputy principals, chairs and secretaries of the Muhammadiyah Elementary and Middle Education Council (MPDM) in Metro City. The results of the study show that the strategy for recruiting and selecting educators has been good. This recruitment activity begins with planning the needs of educators, namely by analyzing the needs of existing teachers, announcement of vacancies for educators, requirements that must be met by prospective educators, selection with various tests, interviews and determining teacher acceptance. The strategy used can be said to be effective for schools, this is proven by the very good quality of teaching staff obtained as expressed by the principal as the executor and decision maker in teacher recruitment activities.
THE CHALLENGES OF THE WORLD OF EDUCATION AGAINST THE DEVELOPMENT OF HUMAN RESOURCES IN ISLAMIC EDUCATION
Authors: Sholeh Lukman , Baharuddin Baharuddin
Published: January 2024

This paper focused on challenging the challenges of the world of education in developing human resource management (MSDM) in Islamic education. The methodology or approach used in this paper uses a library research method or approach. At the same time, data collection was carried out by studying or exploring several journals, books, and documents (both printed and electronic) as well as data sources and or other information that was considered relevant to the study; the purpose of this study was to find out the challenges of the world of education in developing resource management humans were educated in Islam, the results of this study concluded that the challenges of the world of education were several aspects 1. the political challenges, 2. the culture Challenges, 3. the science and technology Challenges, 4. the economy Challenges 5. the society Challenges 6. the value systems challenges
STRATEGY FOR THE DEVELOPMENT OF SUPERIOR MADRASAH BY BUILDING TEACHER'S COMMITMENT TO THE ORGANIZATION
Authors: Widat Faizatul , Fauzi Ahmad , Saleha Latifatus
Published: January 2024

This study aims to determine the form of a superior madrasah development strategy by creating teacher commitment in madrasah. The approach used in this research is a qualitative case study type approach. The informants of this study were the head of the madrasa, the deputy head of the madrasa, teachers and employees of the Miftahul Islam Elementary School. While the data collection methods used are interviews, observation and documentation. The study results show that: first, Madrasah Ibtidaiyah Miftahul Islam involves a strategy for developing madrasas by building teacher commitment; second, the head of the madrasa has a plan for developing superior madrasas by making teacher commitment through; Leader Is Exemplary, Reward and Punishment and Continous improvement.
IMPLEMENTATION OF THE CONCEPT AND DESIGN OF INDEPENDENT CURRICULUM MANAGEMENT IN IMPROVING THE QUALITY OF EDUCATION
Authors: Sholeh Lukman
Published: January 2024

The focus of this research is to challenge the Implementation of the concept and design of Independent Curriculum Management in improving the Quality of Education at the junior high school level. The methodology or approach used in this paper uses a library research method or procedure. At the same time, data collection is carried out by studying and exploring several journals, books, and documents (both printed and electronic) as well as other sources of data and or information that are considered relevant to the study; the purpose of this study is to find out the Implementation of the concept and design of Independent Curriculum Management in improving the Quality of Education, The results of this study concluded that the Implementation of the idea of independent curriculum education in improving the quality of education integrates literacy skills, knowledge skills, skills and attitudes as well as mastery of technology. The independent curriculum is a program expected to restore learning, which offers three characteristics, including project-based learning for developing soft skills and attributes following the profile of Pancasila students, learning on essential materials, and a more flexible curriculum structure.
MANAGEMENT OF QUR'AN LEARNING IN IMPROVING STUDENTS' TAHSIN IN PESANTREN; UMMI PERSPECTIVE METHOD
Authors: Fawaid Achmad , Diana Izzah
Published: January 2024

This study analyses the management of learning the Qur'an through the Ummi approach at Islamic boarding schools. This study uses a descriptive qualitative research method. Data collection techniques in this study are through interviews, observation, and documentation studies. The results of the study show: 1) The planning starts with teacher certification, determine the learning model, and prepares teaching materials (materials) and stages of learning using the Ummi method. 2) The implementation, carried teacher, outdoes teacher discipline, fostering student enthusiasm, facilities, adequate media sources, filling in teacher and student absences and a complete assessment journal. 3) Evaluation, namely the implementation of the exam as a form of completion in learning.
CURRICULUM MANAGEMENT AS CUSTOMER TRUST IN THE QUALITY OF MEMORIZATION OF QUR'AN STUDENT
Authors: Basid Abd. , Kusumawati Ida
Published: January 2024

This study aims to determine the improvement of the quality of memorization of the Qur'an where the number of students who memorize the Qur'an is not following the rules of tajweed and less than optimal quantity and quality of memorization is the focus of this study. This research method aims to determine the effectiveness and quality of memorization of the Qur'an students to find out changes before using the curriculum and after using the curriculum. This study used a qualitative approach and data collection techniques in this study using observation and interviews. Data analysis used is data display, data reduction, and decisions taken. From the results of the study, it can be concluded that the overall curriculum process applied in the Tahfidz Program runs well and can increase the quantity and quality of memorization of the Qur'an students. Although there are some technical obstacles, the existence of a curriculum can help in improving the quality of memorization of the Qur'an students and increasing customer trust in the surrounding environment and community.
PESANTREN-BASED EXPERIENTIAL MARKETING; SENSE EMOTIONAL ANALYSIS IN BUILDING CUSTOMER LOYALITY
Authors: Mundiri Akmal , Firdausy Arij
Published: January 2024

This research aims to produce Pesantren-based experiential marketing; emotional sense analysis in building customer loyalty. The research approach used is a qualitative approach with a case study type. The data that has been collected is analyzed by using the Miles and Huberman data analysis technique which consists of data reduction, data display, and verification. The results of this study indicate that the process of experiential marketing is based on Pesantrens; emotional sense analysis in building customer loyalty is carried out through the provision of stimuli and cognitive consistency. Providing stimuli in Pesantren-based experiential marketing is carried out with osabar, ospectren, and harlah events. Meanwhile building cognitive consistency is done by Exemplary of Kyai, organizational climate and culture of pesantren, and spiritual experience. Dengan demikian, penelitian ini menemukan teori tentang marketing based on spiritual experience.
MARKETING COMMUNICATION STRATEGY FOR ISLAMIC BOARDING SCHOOL-BASED EDUCATIONAL INSTITUTIONS
Authors: Shidiq Muhammad , Saleha Latifatus
Published: January 2024

Communication is an important component in education as a means to connect between educational components. The role of communication in education marketing is a positive interaction that must be built by stakeholders as an effort to maintain the existence of educational institutions. The importance of communication must be built internally in educational institutions and also externally in educational institutions in the form of the community as an effort to build institutional synergy with the community. This research uses descriptive qualitative analysis method . Data collection techniques were carried out through observation and interviews. While the data analysis technique uses Miles and Huberman. The results of the study show that the communication strategy used by Nuris Vocational School has not been successful in the New Student Admissions (PPDB) activities.
In Silico Molecular Docking Analysis of Flavone and Phytol from Vilvam (Aegle marmelos) against Human Hepatocellular Carcinoma (HepG-2) Mitochondrial Proteins
Authors: Anbalagan Saranya , Kanakarajan Sivakumari , Selvaraj Rajesh , Kolappapillai Padmavathy
Published: January 2024

The vilvam fruit is an important source of phyto compounds, that are a good natural resource for curing several health illnesses. Annually, around 906,000 new cases and 830,000 deaths worldwide are attributed to liver cancer, making it one of the most prevalent malignant tumors. Humans' physical and mental well-being, as well as their social and economic advancement, are seriously threatened by and challenged by liver cancer. The molecular interactions between biological chemicals originating from plants and proteins relevant to apoptosis, however, are not well documented in research. Therefore, the objective of this study was to determine the potential biological compounds of flavone and phytol found in the vilvam fruit and examine their interactions with the targeted apoptotic proteins using molecular docking simulation towards liver cancer mitochondrial signalling pathway proteins such as Caspase 3, Caspase 9, Bax, Bcl-2, PARP, p53, and Cytochrome C. Flavone showed a docking score with Caspase 3 (-10.51 kcal/mol), Bax (-9.49 kcal/mol), Bcl-2 (-11.10 kcal/mol), PARP (-10.22 kcal/mol) and p53 (-10.36 kcal/mol), but could not bind with Caspase 9 and Cytochrome C, while phytol could not bind with all the apoptotic proteins. The consequence of Lipinski rule recommends that flavone is the best curative drug for liver cancer. Docking results verify the application of flavone as a potential and natural therapeutic agent to treat diseases.
A Green Raman Spectroscopic Assay Method for The Quantification of Tranexamic Acid in Pharmaceutical Formulations
Authors: Singh P. S. , Lokhande R.S. , Kochrekar D. A.
Published: January 2024

Tranexamic acid (TXA) is a widely used antifibrinolytic agent that is used to prevent and treat excessive bleeding. Current analytical methods for TXA are often time-consuming and require the use of toxic solvents. Raman spectroscopy has the ability to measure TXA because it is a fast and non-destructive analytical method. This research established and validated a green Raman spectroscopic test for TXA measurement. There was no need for harmful solvents because the technique relied on a basic aqueous solution of TXA. Results demonstrated that the technique was linear across the 0.7% to 13.0% concentration range. The method was also shown to be accurate, with results comparable to the orthogonal techniques. The green Raman spectroscopic assay method was applied to the quantification of TXA in pharmaceutical formulations. The results obtained were comparable to those obtained using reference methods. To quantify TXA quickly and accurately, one can use the green Raman spectroscopic test. Since no harmful chemicals are needed for the procedure, it is also eco-friendly. Method has the potential to be used in a variety of settings, including pharmaceutical quality control and research laboratories.
Assessment of cardiovascular risk factors in male androgenetic alopecia: A case control study in a tertiary care hospital of western Odisha
Authors: Madhual Subhasree , Nayak Debabrata , Dalei Sambit Ranjan , Padhi Tanmay , Das Nikhil Ranjan
Published: January 2024

Androgenic alopecia (AGA) is the most common cause of patterned hair loss among males which is characterized by progressive hair loss from the bi-temporal and vertex regions of the scalp. Although previous epidemiological studies found an association between metabolic syndrome (MetS), and cardiovascular disease (CVD) risk among adult AGA male patients, there has been no comprehensive research till now to establish this correlation between AGA and cardiovascular risk and there is a paucity of data regarding this association. Two hundred men were included in the study, N = 100 AGA patients included in the patient group, and the rest in the control group. In both groups, the parameters for MetS such as family history, socioeconomic status, obesity, blood pressure, and lipid profile), and in the presence of the CAA plaques and carotid intima-media thickness (CIMT) using Doppler ultrasonography were established. The degree of AGA was asses by using the Hamilton-Norwood grade (I-VII) system for males. Statistical analysis was performed using the Chi-square test. AGA was found in 11.6% of OPD patients, whereas 3 patients have CAA plaque and 6 cases have C-IMT from the patient's group. There was a statistical association between male AGA with MetS, and insulin-resistant patients (P = 0.001 and 0.0004, respectively). A positive family history of AGA patients, hypertension, DM, and CVD was found to be significantly more frequent in study cases than in the controls (P <0.05). Patients with AGA appear to have a highly prevalent risk of developing CVD and CAA plaque. Therefore, clinical evaluation of each AGA patient’s cases is needed, especially for grade III and above which may help prevent CVD in the future. Timely intervention and lifestyle changes in male AGA patients can fulfil the ultimate objective of reducing cardiovascular complications in the future.
A Study of The Effects of Classroom Structure and Instructional Methods on Students Learning of Trigonometric Concepts in Mathematics
Authors: Kaur Dr Puneet
Published: January 2024

To think in a methodical and logical way, mathematics is an essential skill. On top of that, it may be used to learn new things in many other subjects. Recently, there has been a need to find better ways to teach mathematics, especially trigonometry, at senior high schools (SHSs), in order to increase students' understanding of the subject. Thus, numerous studies on what makes a good teaching style that helps students understand the material are necessary. Research has shown that students in higher education, particularly those at the secondary school level, suffer when teachers are unable to relate to the elements of a meaningful-based teaching approach. This study sheds insight on the ways in which a student's learning environment and instructional approaches affect his or her capacity to learn trigonometry, an area where academic policy-makers and educators are now developing transformational initiatives.The study objectives of this article are founded on the premise that environmental motivating characteristics are necessary to excite students' attention and intellect when learning trigonometry, a real-life method that depends on the size and distance of an object. As a result, this program aims to improve and make better use of two features—the classroom environment and instructional method —in elementary and secondary school settings.
Causal relation and volatility spillover between commodity market and equity market of India using VAR Granger Causality and BEKK-GARCH Model
Authors: Amit Sunil Bhardwaj, Sameer Gupta,
Published: January 2024

The financial markets play a discerning role in accentuating the growth of industry and commerce whereas, a volatile market has whopping reverberations on economic and financial stability of a country. The interconnectedness and reciprocity among the financial markets in economies are veraciously liable for the pricing of securities and provide investors, hedgers and speculators with copious opportunities for portfolio diversification. In this context, the study has been taken up to explore the relationship between the commodity and stock markets of India. The study has used the daily closing prices of MCX iComdex composite index, BSE Sensex and NSE Nifty 50 index from 1st January 2016 to 31st December 2022. The Johansen’s cointegration test estimates the absence of cointegration between the indices under study. The results of VAR Granger Causality Tests substantiate a bi-directional causality between the equity and commodity market of India. Whereas, it refutes any causal relationship between the Sensex and Nifty index. The estimates of BEKK-GARCH model confirm a significant volatility spillover between the two markets. The empirical outcomes of the study have poignant implications for all the stakeholders such as individual and institutional investors, policymakers, government agencies, traders, hedgers and other participants in the financial markets.
McCluskieganj In the Spatial Turn: Rethinking Anglo-Indian Diaspora and Spatial Marginalization
Authors: Rishi Dwivedi Arup Mukherjee, Ratnesh Chaturvedi,
Published: January 2024

Nestled in the secluded terrains of Jharkhand, McCluskieganj stands as a poignant testament to the enigmatic confluence of Anglo-Indian memory and space. Its genesis during the pre-independence era marked an epoch when the quest for a 'promised land' became an urgent yearning within the Anglo-Indian community. However, the allure and lustre surrounding this haven have gradually waned with the passage of time and the handover of governance. The plight of the Anglo-Indians, once beset by myriad social and cultural marginalities, metamorphosed into a distinctly spatial odyssey. Amidst this transformative landscape, a dichotomy emerged: the inexorable pull of metropolitan hubs captivated the younger echelons of the community, while the elders remained tethered to the essence of a place they called 'home'. Within this characterization, the geographical context emerges as an indispensable facet in understanding the Anglo-Indian narrative in McCluskieganj. Any discourse on the disposition of the Anglo-Indians within this enclave remains inherently incomplete without an acknowledgment of the inextricable bond between the community's essence and the geographical expanse of McCluskieganj.

This study endeavours to explore the intricate tapestry of McCluskieganj, delving into the symbiotic relationship between the shifting sands of space and the dynamic evolution of Anglo-Indian identity. Through a prism that interlaces academic inquiry with the lyrical essence of human experience, it seeks to illuminate the spatial chapters within the larger narrative of Anglo-Indian existence, embodying a convergence of history, belonging, and the ethereal essence of place.
Arima Forecasting In Soymeal And Beyond: An Empirical Study Bridging The Path To Millet-Based Forecasting
Authors: Shashank Mishra, Vaishanavee Vartak Dr. Jolly Masih, Dr. Molshree Rathore,
Published: January 2024

Soymeal, a rich source of protein and fiber, held paramount importance in livestock and poultry sectors. Derived post oil extraction from soybean seeds, its production and price dynamics hinged on multiple factors including seed supply-demand, crushing costs, transportation expenses, and competition from alternative feed constituents. The study aimed to employ the Autoregressive Integrated Moving Average (ARIMA) model to forecast soymeal production, import, export, and price trends globally for year 2023 by using data from 2016 to 2022. By combining historical insights with predictive analytics, the paper endeavored to illuminate the prospective trajectory of soymeal dynamics on a global scale, offering valuable insights for stakeholders. Moreover, it is noteworthy that the applicability of the ARIMA forecasting model extends beyond soymeal, encompassing other agricultural commodities such as millets and other minor grains. Millets, celebrated for their nutritional value and resilience, hold immense potential in addressing global food security challenges. The ARIMA model's capability to unravel temporal intricacies and patterns could likewise provide insights into millet production, pricing, and trade, contributing to the sustainable development of diverse agricultural sectors. This research not only enriches our understanding of soymeal dynamics but also underscores the versatility of the ARIMA model for forecasting a spectrum of agricultural commodities, promoting informed decision-making and strategic planning.
THE INFLUENCE OF THE TREATMENT WITH FUNGICIDES ON THE PHYSIOLOGICAL PROCESSES IN PRUNUS PERSICA (L.) BATSCH ATTACKED BY MONILINIA FRUCTIGENA (ADERH. & RUHL.) HONEY
Authors: NICOLAE Ion , BUȘE-DRAGOMIR BUȘE-DRAGOMIR
Published: January 2024

Researches regarding the influence of the treatment with fungicides on the physiological processes were carried out on Prunus persica (L.) Batsch, Redhaven variety, cultivated in the climatic conditions in Oltenia region. The physiological researches were performed on July 20th 2022, both for peach trees treated with Dithane M-45 (0,2%) fungicide and also for the peach trees attacked by Monilinia fructigena (Aderh. & Ruhl.) Honey, in which treatments have not been performed. In the leaves of the plants attacked by the pathogen it was observed that the physiological processes’ intensity (photosynthesis and transpiration intensity) is lower as a result of the effects produced by the pathogen manifested by drying young shoots with the convexity of their top, the presence of brown spots on the fruits and the appearance of the fructifications of the pathogen. In the attacked leaves there were recorded lower values of chlorophyll content, in comparison with the leaves of plants treated with fungicide, thus existing a positive correlation between this content and the photosynthesis intensity.
THE EFFECTS OF THE TREATMENT WITH FUNGICIDES ON THE PHYSIOLOGICAL PROCESSES IN PRUNUS AVIUM L. ATTACKED BY STIGMINA CARPOPHILA (LÉV.) M.B. ELLIS
Authors: NICOLAE Ion , BUȘE-DRAGOMIR Luminița
Published: January 2024

Researches regarding the effects of the treatment with fungicides on the physiological processes were carried out on Prunus avium L.,Carmen variety, cultivated in the climatic conditions in Oltenia region. Physiological research was carried out on June 26 th 2022, on cherry trees treated with the fungicide Dithane M45 (0.2%), in comparison with cherry trees attacked by Stigmina carpophila (Lév.) M.B. Ellis in which no treatments were performed. In the leaves attacked by the pathogen it was noticed that the photosynthesis intensity and transpiration intensity record lower values as a result of the effects produced by the pathogen manifested by the emergence of small pink-purple spots, bounded by a reddish-brown border, that gradually enlarges and become necrotic at the centre. The linear regressions performed between the physiological processes intensity and the photosynthetic active radiation, the leaf temperature and the stomatal conductance show a positive correlation between these. In the attacked leaves there were recorded lower values of chlorophyll content, in comparison with the leaves of plants in which fungicide treatments have been performed.
A STUDY REGARDING HEAVY METALS IN PERENNIAL GRASSES SPECIES HARVESTED FROM PERMANENT MEADOWS IN THE COPȘA MICĂ AREA, ROMANIA
Authors: CARABULEA Vera , VRÎNCEANU Nicoleta Olimpia , OPREA Bogdan Ștefan , COSTEA Mihaela , PLOPEANU Georgiana , MOTELICĂ Dumitru-Marian , FUDULU Ionuț Daniel
Published: January 2024

Copșa Mică is one of the areas known, at national and international level, with a high level of pollution, even though metallurgical activities have been stopped. Heavy metals contamination of the environment is a worldwide concern. This study shows the content of heavy metals (Cd, Pb, Zn and Cu) in two species of perennial grass plants (Dactylis Glomerata L. and Festuca Rubra L.) from permanent meadows in the Copșa Mică area. The estimation of heavy metal content is based on a data set made in 17 points for Dactylis Glomerata L. and 19 points for Festuca Rubra L. harvested from permanent grasslands at different distances from the pollution source. For Dactylis Glomerata L. the Cd content varies between 0.05 mg/kg and 1.21 mg/kg, the Cu values were between 2.80 mg/kg and 5.55. The content of Pb and Zn recorded values between 0.15 mg/kg and 49.6 mg/kg and 34.7 mg/kg and 122 mg/kg, respectively. In Festuca Rubra L., Cd values are between 0.04 mg/kg and 3.07 mg/kg, Cu – 0.29 mg/kg and 7.53 mg/kg. Lead (Pb) and zinc (Zn) values ranged between 0.1 mg/kg and 27.5 mg/kg and 25.8 mg/kg and 131 mg/kg, respectively. The results of this study are important for the estimation of heavy metal accumulation in perennial grass species in permanent grasslands, which are consumed directly by animals and indirectly by the population.
STUDY REGARDING CHEMICAL COMPOSITION OF “PALINCA” PLUM DISITILATE FROM CODRU COUNTRY REGION
Authors: GIURGIULESCU Liviu , SITAR Felicia , ȘIMON Andreea , ȘUGAR Ioan Radu , MONDICI Susana
Published: January 2024

The research was carried out in the Country Codru Region from limit between Maramureș and Satu Mare counties. There was analysed 8 samples of distillates (palinca) from 3 villages Asuaju de Jos. Băița de sub Codru and Ardusat. All samples were collected directed from traditional distillery. Fizico-Chemcial analyses followed alcohol concentration; relative density; total acidity; sulphur dioxid content. methanol and furfurole and total content in Ca. Mg. Fe. Zn. Cu. Ni. Co. K. Cd and Na. Results concluded that traditional “palinca” correspond with legislation regarding chemical composition. methanol was identified in one sample and furfurol was absent in all the samples. concentration in minerals was similar at all the samples and depends by the quality of the water used in technological process.
Evaluation of local expressions of acute phase proteins in white muscle disease in lambs by the immunohistochemical method
Authors: Karatas Ozhan , Akcakavak Gokhan
Published: January 2024

White muscle disease (WMD) and/or nutritional muscular dystrophy is defined as a disease with a generally acute course that results in degeneration and necrosis of the heart muscle. In this study, it was aimed to reveal local tissue expressions of acute phase proteins such as C–reactive protein (CRP), Serum amyloid–A (SAA) and Haptoglobin (Hp) in lambs with WMD. The study material consisted of 27, one–six months old lamb heart tissues, 6 of which were healthy and 21 with WMD. The lambs were necropsied, and the relevant heart samples were taken into neutral formaldehyde. Afterwards, paraffin blocks were obtained by going through routine tissue follow–up processes. Sections were taken from paraffin blocks and stained with Hematoxylin–Eosin (H–E) and Immunohistochemical methods. Histopathologically, control groups exhibited normal histology. Hyaline degeneration, Zenker necrosis, calcification, inflammatory cell infiltration and an increase in connective tissue were detected in the heart tissues of lambs with WMD. Lambs with WMD had significantly increased CRP and SAA proteins compared to control (P<0.01). However, there was no difference between the groups in Hp (P>0.05). In conclusion, local tissue expressions of CRP, SAA and Hp in lambs with WMD were identified immunohistochemically for the first time. It is possible to say that CRP and SAA may play important roles in the pathophysiology of WMD and that CRP and SAA may provide more sensitive results in the diagnosis and prognosis of the disease.
Protective effect of Spirulina in the ovary of rats against Doxorubicin toxicity
Authors: Öztürk Şamil , İrkin Latife Ceyda
Published: January 2024

Doxorubicin (Dox) is an anti–cancer agent used of ovarian, breast, liver, lung cancers and solid tumors such as leukemia and lymphoma treatment. However, since it is an antineoplastic agent with a high toxic effect, it causes toxicity on many organs and tissues in the organism. Spirulina spp. (SP) contains phytopigments such as β–carotene, tocopherols and xanthophylls and is a natural source of vitamin A as well as its anticarcinogenic effect. For these reasons, this study was planned to experimentally reveal the antioxidant and protective effects of SP on Dox–induced reproductive toxicity in female rats. In the study, histopathological evaluation was performed after Hematoxylin–Eosin staining in female rats with Dox toxicity. The distribution of GSK–3β for cell proliferation, HIF–1α for oxidative stress and VEGF for vascularization were evaluated. TUNEL staining was performed to determine apoptosis. It was determined that SP prevented tissue damage on the ovarian tissue of rats with Dox toxicity, and this positive effect was achieved through factors such as oxidative stress (HIF–1α), vascularization (VEGF) and inhibition of cell death (Apoptosis). It has been observed that SP treatment to be applied after chemotherapy is effective in protecting both the developing follicles and the primordial follicle pool.
Preventing ethanol-induced stomach ulcers in rats using Senecio perralderianus leaf extract
Authors: Mamache Walid , Benabdallah Hassiba , Hannachi Ahlem , Boukabes Amel , Bencheikh Amor , Benslama Abderrahim , Amira Hind , Bencheikh Fatima , Amira Smain
Published: January 2024

Senecio perralderianus belongs to the family of Asteraceae and is only found in Algeria. Some species of this family are used to heal gastrointestinal issues in conventional medicine for their antioxidant and anti-inflammatory properties. This research was performed in order to determine if methanolic extract from the leaves of S. perralderianus had any protective effects on gastroenteritis brought on by alcohol consumption. Wistar rats were fed with 100% ethanol orally to induce gastric ulcer, and pre-treated with 50, 100, and 200 mg·kg-1 of the extract in addition to 5 mg·kg-1 of Ranitidine as a positive reference drug. The extract had shown a positive effect to protect ethanol-induced gastric ulcers with a protection percentage of 71 to 88%. In addition, pretreatment of rats significantly increased levels of GSH, CAT, and SOD in vivo as non-enzymatic and enzymatic antioxidants, and also reduced the level of lipid peroxidation. Histopathological sections, which showed the action of the therapeutic extract, substantially confirmed these findings on the reduction of the inflammation zone and the reduction of immune cell filtration caused by ethanol toxicity with increased extract dosages compared to Ranitidine. The antiulcer activity is due to inhibition of oxidative stress and gastritis. It is associated with a total polyphenol, flavonoids, chlorophyll (a, b), and carotenoids substantial amounts.
Subconjunctival deferoxamine for corneal rust deposits associated with ocular siderosis: A case report
Authors: Tandias Rachel , Rossin Elizabeth , Davies Emma
Published: January 2024

Introduction: Ocular siderosis is a vision-threatening condition resulting from intraocular iron toxicity. This case re-establishes a role for subconjunctival deferoxamine, a chelating agent uncommonly used in ophthalmology, as an adjunctive treatment for ocular siderosis.

Case Report: A 37-year-old healthy male presented two months after an injury at work with intermittent pain and blurry vision in the right eye. Presenting visual acuity (VA) was 20/100 in the right eye. With delayed presentation, the patient already had ocular siderosis with corneal rust deposits and retinal damage. The patient underwent pars plana vitrectomy (PPV) with surgical view impaired by corneal deposits and intraocular metallic intraocular foreign body (IOFB) that disintegrated upon attempted removal. At six months postoperatively, VA was 20/70 in the right eye, and examination revealed worsened diffuse, pigmented subepithelial deposits in the central cornea, iris atrophy, cotton wool spots, optic nerve pallor, and a residual IOFB in the anterior vitreous, consistent with worsened ocular siderosis. Superficial keratectomy was performed in combination with repeat PPV to improve surgical visualization and aid in IOFB removal. An amniotic membrane was placed and a subconjunctival injection of deferoxamine was administered. The cornea was well-healed with significantly improved siderosis and no epithelial defects on 2-week postoperative follow-up. Visual acuity was 20/60 at last follow-up two months postoperatively after second surgery.

Conclusion: In treating ocular siderosis, subconjunctival injection of deferoxamine can be a useful addition to surgical IOFB removal to prevent the accumulation of iron deposits in the anterior segment of the eye.
La interpretación constitucional en Ecuador: Una revisión crítica de las teorías y prácticas actuales
Authors: Tapia Vélez Ángel Enrique , Rodríguez Tagle Cristhian Alí
Published: January 2024

El artículo jurídico desarrollado permitió un análisis detallado sobre de las teorías y prácticas actuales de la interpretación constitucional en Ecuador, analizando las diferentes posturas existentes y su impacto en la aplicación de la Constitución. A través de la revisión crítica de las teorías y prácticas de interpretación normativa en Ecuador, una metodología descriptiva bajo un enfoque cualitativo, de naturaleza básica-documental, y la utilización de los métodos Analítico-Sintético, la exegética de lasnormas constitucionales y el método comparativo, se destacó la relevancia de la interpretación constitucional para mantener la coherencia y la unidad del ordenamiento jurídico. Se estableció que esta tarea varía de un país a otro y se basa en la doctrina de la originalidad, es decir, manteniendo la esencia de los redactores de la Carta Magna. Así mismo, al indagar de manera específica en el contexto ecuatoriano, se identificaron los métodos y técnicas utilizadas en esta materia, los cuales sefundamentan en las reglas legislativas nacionales. Estas se complementan entre sí y deben ser utilizadas de manera adecuada para lograr una interpretación integral y sistemática de las normas constitucionales. Por lo tanto, la interpretación constitucional en el Ecuador se considera una herramienta fundamental del sistema jurídico constitucional, ya que brinda a la Corte Constitucional una amplia capacidad para seleccionar los métodos apropiados de interpretación, los que pueden variar con el tiempo en función de la doctrina y la jurisprudencia relacionada. Además, esta herramienta posibilita la investigación del derecho establecido en las leyes constitucionales y explora todas las facetas que abarcan su contenido jurídico y social, fomentando el uso de técnicas y enfoques que garanticen los derechos de los ciudadanos ecuatorianos.
La Salud en el Ecuador como derecho fundamental ante la Emergencia Sanitaria SARS-COV-2
Authors: Cevallos Sánchez Gissela Alexandra , Alvarado Moncada Zoila Felícita
Published: January 2024

Este trabajo investigativo enfocó su estudio en el análisis crítico, doctrinario, jurídico y comparativo de las principales afectaciones y afecciones que ocasionó el Sars-Cov-2, ante las debilidades que afrontaron los estados en relación a las garantías constitucionales al Derecho Humano a la Salud. La metodología cualitativa a través de la revisión documental y la aplicación de los métodos analítico-sintético, histórico-comparativo, permitió efectuar un estudio de cada parte del proceso, a fin de obtener un resultado general de las mismas, a partir de la comprensión de los hechos históricos y comparativos del tema que establecen de forma explícita, un enfoque general sobre la responsabilidad del Estado frente al Derecho a la Salud pública. El sistema de salud pública en el Ecuador, debe ser considerado prioritario y su financiamiento debe provenir mayormente del presupuesto que asigna el Estado a la cartera de salud pública, de tal manera que se puedan implementar programas de atención sanitaria objetivos, que enfoquen la atención de emergencias como el Covid-19, y que no tomen por sorpresa la fragilidad del sistema de salud pública. Este presupuesto debe destinarse especialmente a la contratación de personal especializado, equipos médicos para la operativización de hospitales y medicinas, que garanticen una atención prioritaria en cuanto al sistema de salud a los ciudadanos.
Análisis de la operatividad y mantenimiento de piscinas de la ciudad de Maracaibo, Venezuela
Authors: Carrasquero Ferrer Sedolfo , Mendoza Guillén Allen , Pino Rodríguez Jean , Jativa Castillo Héctor , Díaz Montie Altamira
Published: January 2024

Las piscinas deben estar constantemente reguladas por las autoridades para proteger la calidad del agua y la salud pública. El objetivo de esta investigación fue analizar la operatividad y mantenimiento de piscinas ubicadas en la ciudad de Maracaibo, Venezuela, en tres áreas: sistema de tratamiento y recirculación, seguridad, y sistema de mantenimiento y limpieza, de acuerdo a lo establecido en la normativa venezolana vigente. Para la recolección de datos en el diagnóstico se utilizaron las técnicas de observación directa y como instrumento una guía de observación con escala de estimación, analizando nueve aspectos como: ubicación, apariencia de las aguas, estructura del vaso, materiales y dimensiones, drenaje del agua, mantenimiento básico, sistema de tratamiento, provisiones de las instalaciones y operadores, equipo de rescate y piscina para niños, agrupados en tres áreas, efectividad del tratamiento y recirculación, seguridad y efectividad en el mantenimiento y limpieza. Se encontró que un 80% de las unidades de estudio, presentaron en general buenas condiciones en sus instalaciones, calificadas según el instrumento con 80,5 puntos en promedio; sin embargo, ciertas piscinas presentaron deficiencias en algunos aspectos, sobre todo en aquellos relacionados con la apariencia del agua, ubicación, sistema de drenaje y en la mayoría de las piscinas, el sistema de tratamiento. Se concluye que las unidades de estudio fueron medianamente seguras cumpliendo en gran parte con los requisitos exigidos por la normativa venezolana en cuanto a los aspectos materiales, dimensiones y equipos de rescate.