bluuebunny/crossref_metadata_2025 huggingface dataset:
Simulation of Delamination Evolution of Slab Ballastless Track under Vertical Impact
Authors: Liu Yu , Xu Qianqi , Sun Xiaodan , Yang Guotao , Zhao Guotang
Published: June 2021

During the running of a high‐speed train, the wheel may bounce on the rail due to the track irregularity. The wheel bounce could generate a vertical impact, leading to the initiation and expansion of delamination between layers of the track structure. In this paper, the evolution of the interfacial damage and delamination subjected to the vertical impact is simulated using finite element analysis (FEA). In the FEA, a bilinear cohesive zone model (CZM) is adopted to simulate the interface between the track slab and the CA mortar layer. For different levels of impact energy, the contact force, vertical deformation, absorbed energy, area of interfacial damage, and area of delamination are calculated and compared. The effects of the tangential and normal stiffness of the interface on the distribution of interfacial damage and delamination are investigated. The results show that the contact force, vertical deformation, absorbed energy, area of interfacial damage, and area of delamination increase with the increase of the impact energy. The area of interfacial damage in the compression stage is closely related to the tangential stiffness, whereas the area of delamination depends on the normal stiffness. The normal stiffness that gives the largest area of delamination is recommended to be taken as the lower bound of the normal stiffness for both controlling the delamination and preventing an exceedance of the track irregularity limit.
Evaluation of Chest CT Scan as a Screening and Diagnostic Tool in Trauma Patients with Coronavirus Disease 2019 (COVID-19): A Cross-Sectional Study
Authors: Abdolrahimzadeh Fard Hossein , Mahmudi-Azer Salahaddin , Sefidbakht Sepideh , Iranpour Pooya , Bolandparvaz Shahram , Abbasi Hamid Reza , Paydar Shahram , Sabetian Golnar , Mahmoudi Mohamad Mahdi , Zare Masoume , Shayan Leila , Salimi Maryam
Published: June 2021

Background. The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT  scan as a screening measure of COVID-19 in trauma patients. Methods. This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT scans were evaluated in a blinded manner, and the main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two Radiological Society of North America (RSNA) categories with the highest probability of COVID-19 pneumonia (i.e., typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID-19 pneumonia into “negative CT scan group.” Results. Chest CT scan had a sensitivity of 68%, specificity of 56%, positive predictive value of 34.8%, negative predictive value of 83.7%, and accuracy of 59.3% in detecting COVID-19 among trauma patients. Moreover, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals, a sensitivity of 100%, specificity of 66.7%, and negative predictive value of 100% were obtained (

p

value: 0.05). Conclusion. Findings of the study indicated that the CT scan’s sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 compared with nontraumatic people.
Comparison of Percutaneous Kyphoplasty with or without Pedicle Screw Fixation in Osteoporotic Thoracolumbar Vertebral Fractures: A Retrospective Study
Authors: Huang Dichao , Ying Jichong , Xu Dingli , Chen Jianming , Liu Jianlei , Yu Tianming , Zhuang Yunqiang , Zhou Long
Published: June 2021

Background. Osteoporotic thoracolumbar compression fractures have become a great social burden due to the aging tendency of population. This study is aimed at comparing the clinical and radiological outcomes of percutaneous kyphoplasty with or without pedicle screw fixation in patients with osteoporotic thoracolumbar fractures. Hypothesis. There is a difference in clinical outcomes between percutaneous kyphoplasty with pedicle screw fixation and percutaneous kyphoplasty. Methods. This retrospective study included 87 patients who received percutaneous kyphoplasty with or without pedicle screw fixation between October 2015 and October 2017 at Ningbo No.6 Hospital and were followed for 2 years. A total of 40 patients received percutaneous kyphoplasty with pedicle screw fixation (PKPF group), and the other 47 patients had percutaneous kyphoplasty only (PKP group). The outcomes were measured using the visual analogue scale (VAS), Oswestry Disability Index (ODI), Cobb angle (CA), and anterior vertebra height rate (AVHr), which were calculated at preoperative admission and each follow-up visit. Complications including postoperative back pain, refracture, and fixation failure were collected from medical records. Results. There was no significant difference in baseline characteristics or preoperative data between the two groups (

p
<
0.05

) but significantly better improvements in VAS, ODI, CA, and AVHr at 12- and 24-month follow-up visits in the PKPF group compared with those of the PKP group. 23 (48.9%) patients in the PKP group had complications, whereas only 5 (12.5%) patients in the PKPF group presented complications including 2 postoperative back pain and 1 fixation failure (

p
=
0.04

). Conclusions. PKPF obtained longer correction and better improvement in VAS, ODI, and CA in patients with osteoporotic thoracolumbar vertebral fractures than PKP.
The Hermitian Kirchhoff Index and Robustness of Mixed Graph
Authors: Lin Wei , Zhou Shuming , Li Min , Chen Gaolin , Zhou Qianru
Published: June 2021

Large-scale social graph data poses significant challenges for social analytic tools to monitor and analyze social networks. The information-theoretic distance measure, namely, resistance distance, is a vital parameter for ranking influential nodes or community detection. The superiority of resistance distance and Kirchhoff index is that it can reflect the global properties of the graph fairly, and they are widely used in assessment of graph connectivity and robustness. There are various measures of network criticality which have been investigated for underlying networks, while little is known about the corresponding metrics for mixed networks. In this paper, we propose the positive walk algorithm to construct the Hermitian matrix for the mixed graph and then introduce the Hermitian resistance matrix and the Hermitian Kirchhoff index which are based on the eigenvalues and eigenvectors of the Hermitian Laplacian matrix. Meanwhile, we also propose a modified algorithm, the directed traversal algorithm, to select the edges whose removal will maximize the Hermitian Kirchhoff index in the general mixed graph. Finally, we compare the results with the algebraic connectivity to verify the superiority of the proposed strategy.
Systemic Thrombolysis for Treatment of Postpartum Saddle Embolism Complicated by Postpartum Hemorrhage: A Case Report and Brief Literature Review
Authors: Mostajeran Kathy , Boswell Hillary , Haidar Ziad
Published: June 2021

Venous thromboembolic events (VTE), specifically pulmonary embolisms, account for a significant portion of maternal morbidity and mortality. Due to the procoagulant physiological changes that occur, pregnancy and the postpartum period are known risk factors for thromboembolic events. The risk is greatest during the first-week postpartum and remains elevated for up to six weeks as compared to the general population. Treatment guidelines regarding the use of thrombolytics for massive pulmonary embolism occurring in pregnancy and the postpartum are not well established. In nonpregnant populations, thrombolytic agents are well known to decrease the mortality in the setting of a massive pulmonary embolism. However, in the absence of management guidelines, thrombolysis in pregnancy remains guided by case reports and case series. We present a case of a massive pulmonary embolism (PE) causing hemodynamic instability during the postpartum period treated with tissue plasminogen activator (tPA). The case was complicated by delayed postpartum hemorrhage successfully managed with the uterotonic methylergometrine. The patient was started on oral anticoagulation and continued for six months without recurrent VTE. Our case demonstrates a rare occurrence of a saddle embolism after a vaginal delivery within the first postpartum week which was successfully managed with the use of systemic thrombolysis and minimal intervention to manage the iatrogenic delayed postpartum hemorrhage. To the authors’ knowledge, no other similar case report exists. This case highlights the need to develop guidelines for the use of thrombolysis in mothers who present with massive pulmonary embolus and a noninvasive means to manage adverse bleeding events in the puerperium.
Evaluations of a Weighted Average of Gauss Sums
Authors: Shao Wen-Kai , He Yuan
Published: June 2021

In this paper, we perform a further investigation for a weighted average of Gauss sums. By making use of some properties of the cotangent function and the Bernoulli polynomials, we explicitly evaluate the weighted average of Gauss sums in terms of the special values of Dirichlet

L

-functions at positive integers.
Spatiotemporal Characteristics of Reservoir‐Induced Earthquakes Using P‐Wave Velocity Structures
Authors: Feng Zhiren , Jin Bo , Lei Hongfu , Liu Di
Published: June 2021

In this study, through the seismic phase observation report obtained by a river reservoir seismic network from September 2012 to July 2015, the joint inversion method of source and velocity structure is employed, combined with the regional seismic geological environment data. Such method gives the P‐wave velocity structure of different sections in the reservoir area and tries to find out the impact range of the reservoir water depth. And the impact of reservoir water infiltration on crustal medium is discussed. The obtained location results show that the earthquake activity is mainly concentrated in the first reservoir tail and the second reservoir head. As such, the spatial distribution characteristics of the recorded earthquakes are given, and the resolution results of detection board at different depths are speculated and discussed.
On Opial-Type Inequalities for Superquadratic Functions and Applications in Fractional Calculus
Authors: Nazeer Waqas , Farid Ghulam , Salleh Zabidin , Bibi Ayesha
Published: June 2021

We have studied the Opial-type inequalities for superquadratic functions proved for arbitrary kernels. These are estimated by applying mean value theorems. Furthermore, by analyzing specific functions, the fractional integral and fractional derivative inequalities are obtained.
Flow, Wind, and Stochastic Connectivity Modeling Infectious Diseases
Authors: Udriste C. , Tevy I. , Rasheed A. S.
Published: June 2021

We study in this paper the trends of the evolution of different infections using a SIR flow (first‐order ODE system), completed by a differential inclusion, a geodesic motion in a gyroscopic field of forces, and a stochastic SIR perturbation of the flow (Itô ODE system). We are interested in mathematical analysis, bringing new results on studied evolutionary models: infection flow together with a differential inclusion, bounds of evolution, dual description of disease evolution, log‐optimal and rapid path, epidemic wind (geometric dynamics), stochastic equations of evolution, and stochastic connectivity. We hope that the paper will be a guideline for strategizing optimal sociopolitical countermeasures to mitigate infectious diseases.
Sensitivity Analysis and Numerical Simulation Study on Main Controlling Factors of Surface Movement and Deformation in Strip Filling Mining under Thick Unconsolidated Layers
Authors: Sun Dequan , Wu Quanlin , Li Xiaoyan , Zhang Zhaomin , Xu Xiaotian , Li Yang , Wu Quansen
Published: June 2021

In many mining areas, there is a lot of pressed coal under buildings, railways, and water bodies, and there are geological conditions of thick unconsolidated layers, so the surface subsidence has certain particularity. The key to solve the problem of pressed coal is the control technology of surface subsidence. The development of strip filling technology provides a kind of economical and effective surface subsidence control technology. With the passage of time, the natural weathering, flow, and fracture of some coal pillars may lead to the instability and failure of some coal pillars. Therefore, the selection of filling parameters plays an important role in the stability of coal pillars. In order to study the influence factors of surface movement and deformation, considering the influence factors of filling rate, key layer thickness, filling body strength, and unconsolidated layer thickness, FLAC 3D was used to simulate the surface movement deformation, and the orthogonal test method was used to analyze the simulation results, and the sensitivity of the main control factors affecting the surface deformation affected by strip filling mining was studied. The results show that the order of importance of the four factors on the four surface movement and deformation parameters is filling rate > key layer thickness > filling body strength > unconsolidated layer thickness. The influence of these four factors on the surface movement and deformation parameters is gradually decreasing, but the influence degree of different factors has drawn a certain gradient.
Ecological Security Assessment Based on Remote Sensing and Landscape Ecology Model
Authors: Liu Pei , Zhang Xiaoying , Ma Chao , Zhang Hebing , Han Ruimei , Lu Xiaofeng
Published: June 2021

The various ecological processes of human beings are not only restricted by the landscape pattern on the regional scale but also affect the local and regional landscape together with global climate change. To date, most of the research on ecological security is based on the pressure‐state‐response (PSR) model, while there were a few studies based on the landscape ecology model approach. In addition, there has been little literature focus on the dynamic change process of ecological security, especially the simulation and prediction of the future development trend of ecological security. The purpose of this research is to establish a landscape ecological security evaluation method based on grid division, be aimed at breaking the inherent drawbacks of the administrative region as a unit mode approach, anticipated to better reflect the landscape ecological security status of the study area. A complex framework was constructed by integrating random forest algorithm, Fishnet model, landscape ecology model, and CA‐Markov model. Multitemporal remote sensing data were selected as a data source, and land use maps of the study area were obtained through the random forest machine learning algorithm firstly. And then, the study area is divided into 307 grids of 2 km × 2 km using the Fishnet model. Next, the landscape disturbance index, landscape vulnerability index, and landscape loss index are used on the grid scale to establish a landscape ecological security evaluation model. Finally, ecological security assessment of Zhengzhou city was carried out, and the distribution map of the landscape ecological status in 1986, 1996, 2006, 2016, and predicted for 2026 was obtained. The results of the study showed that, as time goes by, the areas with high ecological safety gradually decrease. It is predicted that by 2026, the ecological security level of Zhengzhou will be dominated by lower ecological security areas. The research results can provide basic information and decision support for government agencies and land use planners to ensure responsible and sustainable development of the urban environment and ecology.
Energy-Aware Flexible Job Shop Scheduling Using Mixed Integer Programming and Constraint Programming
Authors: Ham Andy , Park Myoung-Ju , Kim Kyung Min
Published: June 2021

Compromising productivity in exchange for energy saving does not appeal to highly capitalized manufacturing industries. However, we might be able to maintain the same productivity while significantly reducing energy consumption. This paper addresses a flexible job shop scheduling problem with a shutdown (on/off) strategy aiming to minimize makespan and total energy consumption. First, an alternative mixed integer linear programming model is proposed. Second, a novel constraint programming is proposed. Third, practical operational scenarios are compared. Finally, we provide benchmarking instances, CPLEX codes, and genetic algorithm codes, in order to promote related research, thus expediting the adoption of energy-efficient scheduling in manufacturing facilities. The computational study demonstrates that (1) the proposed models significantly outperform other benchmark models and (2) we can maintain maximum productivity while significantly reducing energy consumption by 14.85% (w/o shutdown) and 15.23% (w/shutdown) on average.
Differential Metabolomics and Network Pharmacology Analysis of Silkworm Biotransformation between Mulberry Leaves and Silkworm Droppings
Authors: Li Mingqian , Chen Lin , Dai Yuntao , Li Jiacheng , Li Fei , Li Qun , Yu Zhihong , Chai Kequn , Zhu Yongqiang
Published: June 2021

Silkworm droppings are the product of mulberry leaves digested by silkworm intestines, which are an important medicinal resource in traditional Chinese medicine (TCM). The contents of total fat, fat acids, crude protein, amino acids, and secondary metabolites of obtained mulberry leaves and silkworm droppings were analyzed by HPLC, GC-MS, and UHPLC-Q-TOF MS. The target genes and enriched pathways related to significantly changed compositions between mulberry leaves and silkworm droppings were analyzed by network pharmacology. High unsaturated C18 : 3 fatty acids were transformed to low unsaturated C18 : 1 from mulberry leaves to silkworm droppings. Only lysine and 17 mini-peptides had significantly higher content in silkworm droppings than in mulberry leaves. There were 36 common target genes or the different compounds between mulberry leaves and silkworm droppings. The main pathways of mulberry leaf were enriched in antivirus and anticancer properties, while the pathways of silkworm droppings were enriched in hormone regulation and signal transduction.
High-Capacity Reversible Data Hiding in Encrypted Images Based on Prediction Error Compression and Block Selection
Authors: Wang Xu , Li Li-Yao , Chang Ching-Chun , Chen Chih-Cheng
Published: June 2021

The popularity of cloud computing has impelled more users to upload personal data into the cloud server. The need for secure transmission and privacy protection has become a new challenge and has attracted considerable attention. In this paper, we propose a high-capacity reversible data hiding scheme in encrypted images (RDHEI) that compresses prediction errors in usable blocks of block-based encrypted images. On the content owner side, the original image is divided into

2
×
2

sized blocks, and each block is encrypted by block-based modulation. On the data hider side, an efficient block-based predictor is utilized to generate prediction errors. The Huffman coding technique is introduced to compress prediction errors in the usable blocks to embed abundant additional data. On the receiver side, the additional data can be totally extracted with a data hiding key and the original image can be losslessly recovered with an image encryption key. Experimental results demonstrate that the embedding rate of our proposed scheme is significantly improved compared to those of state-of-the-art schemes.
Assessment of Selected Matrix Metalloproteinases (MMPs) and Correlation with Cytokines in Psoriatic Patients
Authors: Michalak-Stoma Anna , Bartosińska Joanna , Raczkiewicz Dorota , Kowal Małgorzata , Krasowska Dorota , Chodorowska Grażyna
Published: June 2021

Metalloproteinases (MMPs) and cytokines have a great impact on the pathogenesis of psoriasis. Cytokines, as key mediators of inflammation and autoimmune processes, play a crucial role in the regulation of MMP expression in different cell types. Parallel, MMPs have an influence on cytokine production. This interaction was not well recognized in psoriatic patients. Our study is aimed at assessing the selected serum MMP levels and their correlations with cytokine levels in the serum of psoriatic patients. We observed a significantly elevated level of pro-MMP-1 and MMP-9 in psoriatic patients’ serum in comparison to the control group. We did not observe any statistically significant differences of MMP-3 and pro-MMP-10 between the psoriatic patients and the control group. We did not observe any statistically significant differences in all the studied MMP levels between the patients with and without psoriatic arthritis (PsA). MMP-3 level correlated positively with proinflammatory cytokines, i.e., IL-12p/70, IL-17A, and TNF-α as well as MMP-3 and pro MMP-1 correlated positively with IL-4 in the psoriatic patients. In the control group, a positive correlation between pro-MMP-1 and TNF-α was found. These results confirm MMPs and Th1 and Th17 cytokine interaction in the inflammatory regulation in psoriasis.
Efficacy of Sesame (Sesamum indicum L.) in the Management of Incomplete Abortion: An Open-Label Randomized Controlled Clinical Trial
Authors: Aghababaei Zahra , Nejatbakhsh Fateme , Mazaheri Mohammad , Shirazi Mahboobeh , Feizi Awat , Bozorgi Mahbubeh , Bioos Soodabeh
Published: June 2021

Background: Incomplete abortion is a common complication of pregnancy. Sesamum indicum L. is a widely used emmenagogue herb. Objectives: We designed a clinical trial to evaluate the efficacy of sesame for the removal of retained products of conception (RPOC). Methods: In this randomized, open-label, and controlled trial, 45 patients received sesame powder as an intervention group and 45 patients received expectant management as a control group for 5 days. The primary outcome measure was complete resolution of RPOC assessed by sonography. Secondary outcome measures were severity of patients’ vaginal bleeding and pain. Results: 84.1% had complete resolution of RPOC in the sesame group, while 26.2% had complete resolution of RPOC in the control group, which was statistically significant (p < 0.001). Moreover, patients in the sesame group showed a significantly more decreasing trend in pain and vaginal bleeding compared to the control group (p < 0.001). Conclusion: Sesame had a significant effect on the removal of RPOC and the reduction of pain and vaginal bleeding.
Effect and Safety of Remifentanil Patient-Controlled Analgesia Compared with Epidural Analgesia in Labor: An Updated Meta-Analysis of Randomized Controlled Trials
Authors: Zhang Peijun , Yu Zhiqiang , Zhai Meili , Cui Jian , Wang Jianbo
Published: June 2021

Purpose: The study was aimed to systematically assess the effect and safety of remifentanil patient-controlled analgesia (rPCA) versus epidural analgesia (EA) during labor. Methods: Eligible trials were retrieved from PubMed, EMBASE, ScienceDirect, and Cochrane Library before April 2020. The primary outcomes were patient satisfaction with pain relief and average visual analog scale (VAS) pain scores during labor; the secondary outcomes were rate of spontaneous delivery, oxygen desaturation, maternal hyperthermia, and neonatal Apgar scores <7 at 1 and 5 min. Results: Eleven studies involving 3,039 parturients were included. We found that parturients receiving rPCA were similarly satisfied with pain relief compared to those receiving EA (standardized mean difference: −0.19; 95% confidence interval [CI]: −0.57, 0.18), though had significantly higher VAS pain scores during labor (weighted mean difference: 1.41; 95% CI: 0.32, 2.50). The rate of spontaneous delivery was comparable. rPCA increased the risk of maternal oxygen desaturation (risk ratio [RR]:3.23, 95% CI: 1.98, 5.30). There was no statistical significance regarding hyperthermia (RR: 0.49, 95% CI: 0.24, 1.01). No significant difference was found for neonatal Apgar scores <7 at 1 and 5 min. Conclusion: rPCA could be an optional alternative for pain relief to EA without worsening maternal satisfaction with pain relief, delivery modes, or neonatal morbidity. However, rPCA was associated with higher pain intensity during labor and higher incidence of maternal oxygen desaturation. The routine use of rPCA in labor must be armed with close respiratory monitoring. Continued well-designed studies are required to provide more robust evidence.
Concomitant Nitrofurantoin-Induced Autoimmune Hepatitis and Interstitial Lung Disease
Authors: Carvalho de Matos Andreia , Pais Macedo Cristiane , Afonso Mendes Patrícia , Cipriano Maria Augusta , Paiva Artur , Simão Adélia
Published: June 2021

Antibiotics are known to cause adverse reactions, but multiple organ involvement associated with nonspecific symptoms can lead to a delay in diagnosis. A definitive correlation between each toxin and its effects is difficult to establish due to concomitant potential toxins in the circulation. This article highlights an uncommon case of concomitant nitrofurantoin-induced autoimmune hepatitis and lung fibrosis that fulfills the definitive clinical criteria for diagnosis, presenting histological, imagiological, and immunological evidence of nitrofurantoin-induced toxicity. It occurred in a 68-year-old woman with extended nitrofurantoin intake for urinary tract infection prophylaxis who presented with progressive exercise dyspnea and jaundice. Similar published cases are also reviewed in this article.
Pulmonal-arterielle Hypertonie: Initiale Kombinationstherapie bei atypischen Patienten nicht erzwingen
Authors: Herkenrath Simon-Dominik
Published: June 2021

Background: Background: Although combination therapy is the gold standard for patients with pulmonary arterial hypertension (PAH), some of these patients are still being treated with monotherapy. Methods: We conducted a retrospective analysis at four German PH centres to describe the prevalence and characteristics of patients receiving monotherapy. Results: We identified 131 incident PAH patients, with a mean age of 64 ± 13.8 years and a varying prevalence of comorbidities, cardiovascular risk factors and targeted therapy. As in other studies, the extent of prescribed PAH therapy varied with age and coexisting diseases, and younger, so-called «typical» PAH patients were more commonly treated early with combination therapy (48% at 4–8 months). In contrast, patients with multiple comorbidities or cardiovascular risk factors were more often treated with monotherapy (69% at 4–8 months). Survival at 12 months was not significantly associated with the number of PAH drugs used (single, dual, triple therapy) and was not different between «atypical» and «typical» PAH patients (89% vs. 85%). Conclusion: Although «atypical» PAH patients with comorbidities or a more advanced age are less aggressively treated with respect to combination therapy, the outcome of monotherapy in these patients appears to be comparable to that of dual or triple therapy in «typical» PAH patients.
Diagnosis of Helicobacter pylori Infection by the Arrangement of Collecting Venules Using White Light Endoscopy: Evaluation of Interobserver Agreement
Authors: Garcés-Durán Rodrigo , Galdín-Ferreyra Martín , Delgado-Guillena Pedro Genaro , Cuatrecasas Miriam , Córdova Henry , García-Rodríguez Ana , Rodrigo-Calvo Maria-Teresa , Jimeno-Ramiro Mireya , Araujo Isis Karina , Ginès Angels , Llach Josep , Fernandez-Esparrach Gloria
Published: June 2021

Background: Regular arrangement of collecting venules (RAC) in gastric mucosa accurately identifies patients without Helicobacter pylori (H pylori) infection. The aim of our study was to evaluate the reproducibility of RAC using white light endoscopy without magnification, in a European country, and to assess the impact of proton pump inhibitors (PPIs). Methods: A multicenter prospective study with image capture of the distal lesser gastric curvature and gastric biopsies was performed. The presence of starfish-like minute points regularly distributed throughout lesser curvature was considered as RAC positive (RAC+). A set of 20 images was used for the training phase and inter and intra-observer agreements were calculated. Results: 174 patients were included and 85 (48.9%) were taking PPIs. Kappa values for interobserver and intra-observer agreements were substantial (0.786) and excellent (0.906), respectively. H. pylori infection was diagnosed in 29 patients (16.7%): 10/85 with PPIs and 19/89 without PPIs (11.8% vs. 21.3%; p = 0.09). All RAC + patients were free of H. pylori infection, with a sensitivity and negative predictive value of 100%, regardless of PPI intake. Conclusion: The endoscopic diagnosis of H. pylori by RAC is an easy-to-learn and highly reproducible technique, even with PPI intake. Our results warrant RAC as a real-time diagnostic method for H. pylori-negative infection in Western practice.
СУЧАСНІ МЕТОДИ ФІЗИЧНОЇ РЕАБІЛІТАЦІЇ ФУНКЦІЇ ХОДЬБИ ПІСЛЯ ГОСТРОГО ПОРУШЕННЯ МОЗКОВОГО КРОВООБІГУ
Authors: Голяченко А. О. , Трофимчук Я. Ю.
Published: June 2021

У роботі досліджено основні аспекти відновлення функції ходьби засобами фізичної терапії у хворих після перенесеного гострого порушення мозкового кровообігу. Включення в програму ранньої мобілізації хворих із гострим порушенням мозкового кровообігу методів кінезитерапії дозволяють говорити про значну ефективність запропонованої програми фізичної реабілітації порівняно зі загальноприй­ня­тою програмою.
ДО ПРОБЛЕМИ РОЗВИТКУ КОРОТКОЗОРОСТІ В СУЧАСНОЇ МОЛОДІ
Authors: Кирилова Л. П. , Пилипишин О. І.
Published: June 2021

У статті проаналізовано причини поширеності короткозорості серед молоді. Встановлено причини та фактори, що сприяють виникненню даного захворювання. Висвітлено причини появи даної патології, аналіз розвитку хвороби та методи її профілактики.
ПСИХОЛОГІЧНІ ОСОБЛИВОСТІ СПІЛКУВАННЯ МЕДИЧНОЇ СЕСТРИ І ПАЦІЄНТІВ ІЗ ПОЗИЦІЙ МЕДИЧНОЇ ДЕОНТОЛОГІЇ
Authors: Тишкевич-Львова Є. В.
Published: June 2021

У статті висвітлено проблему вибудовування комунікації сестринського персоналу з пацієнтами, підкрес­лено принципове значення спілкування для лікувального процесу. Відображено значущість вміння медичної сестри зрозуміти і вислухати пацієнта, що здійснює сприятливий вплив на встановлення психо­логічного контакту.
ПРИКЛАДНІ АСПЕКТИ МЕДСЕСТРИНСЬКОГО ПРОЦЕСУ У ВІДДІЛЕННІ ЗАГОТІВЛІ ДОНОРСЬКОЇ КРОВІ ТА ВИГОТОВЛЕННЯ ЇЇ КОМПОНЕНТІВ
Authors: Лучишин Н. Ю. , Гончаренко Я. В.
Published: June 2021

У статті проаналізовано зміст медсестринського процесу в роботі медичної сестри відділення заготівлі донорської крові та виготовлення її компонентів. Зауважено, що робота цього відділення повинна бути доповнена правильно організованою діяльністю медичних сестер на всіх етапах: відбору і підготовки донора, заготівлі крові та її компонентів, спостереження за донором у процесі донації та встановлення сестринського діагнозу у випадку виникнення реакцій.
ПОРУШЕННЯ СЕРЦЕВОГО РИТМУ У ХВОРИХ З ГОСТРОЮ ІШЕМІЄЮ МІОКАРДА, ЩО РОЗВИНУЛИСЬ НА ТЛІ КОМОРБІДНОЇ АРТЕРІАЛЬНОЇ ГІПЕРТЕНЗІЇ ТА ЦУКРОВОГО ДІАБЕТУ
Authors: Бадюк Н. В. , Гребеник М. В.
Published: June 2021

Гострий коронарний синдром (ГКС) є однією з провідних причин смерті в світі. Розвиток гострої ішемії міокарда супроводжується  порушеннями ритму серця  (ПРС), особливо в умовах коморбідності. У більшості хворих (до 80%) ІМ розвивається на тлі артеріальної гіпертензії (АГ), а у 50 % - цукровий діабет (ЦД).
ЗМІНИ БІОХІМІЧНИХ ПОКАЗНИКІВ АЗОТОВИДІЛЬНОЇ ФУНКЦІЇ НИРОК ЩУРІВ ПРИ ТРИВАЛОМУ ВВЕДЕННІ ТЕРАПЕВТИЧНИХ ДОЗ НАЛБУФІНУ
Authors: Вільхова І. В. , Матешук-Вацеба Л. Р. , Канцер О. В. , Подолюк М. В. , Бекесевич А. М. , Гресько Н. І.
Published: June 2021

Резюме. З огляду на проблему наркоманії, яка є однією з найбільш актуальною у суспільстві, заслуговує уваги дослідження морфофункціонального стану нирки при тривалому вживанні опіоїдів.

Мета дослідження – вивчити зміни біохімічних показників азотовидільної функції нирки щура при тривалому введенні терапевтичних доз налбуфіну.

Матеріали і методи. Дослідження виконані на 70 білих статевозрілих щурах-самцях масою 180–260 г. Налбуфін вводили дослідним тваринам у терапевтичних дозах упродовж 12-ти тижнів. Кожні два тижні визначали добовий діурез, креатинін сечі, креатинін сироватки крові, сечовину сироватки крові та розраховували швидкість клубочкової фільтрації. Отримані дані проходили перевірку на нормальність розподілу із використанням показників коефіцієнтів асиметрії та ексцесу, а також із використанням критерію Шапіро – Уїлка.

Результати. Введення терапевтичних доз налбуфіну впродовж 12-ти тижнів призводить до змін біохімічних показників сечовини та креатиніну сироватки крові щурів, креатиніну сечі, добового діурезу та швидкості клубочкової фільтрації. Між значеннями показників сечовини та креатиніну сироватки крові було виявлено достовірний, прямий, виражений зв’язок та максимальне зростання на 6-му та 8-му тижнях експерименту. Виявлено різке зниження швидкості клубочкової фільтрації через 4 тижні експерименту, відновлення цього показника на 6-му тижні та наступне поступове зниження, що наприкінці 12-го тижня було достовірно нижчим порівняно з контрольною групою. Показники креатиніну сечі різко знижені на 4-му тижні експерименту, зростають на 6-му та 8-му тижнях експерименту та у наступних термінах знижуються до показників контрольної групи.

Висновки. Отримані результати свідчать по зміни азотовидільної функції нирки на різних термінах введення терапевтичних доз налбуфіну.
EFFECTS OF HEMOTOXIC SNAKE BITE ENVENOMATION ON HAEMATOLOGICAL PARAMETERS VARIABILITY IN PREDICTING COMPLICATIONS
Authors: Harikrishnan M. P. , Anil Kumar C. R. , Anand M. K. , Earali J.
Published: June 2021

Background. Snake bite envenomation is a major public health problem in India with a high mortality rate. The major complications following a hemotoxic snake bite are disseminated intravascular coagulation (DIC), shock, acute kidney injury (AKI), acute respiratory distress syndrome (ARDS) and coagulopathy. The study explores a possible correlation of the haematological parameters studied to complications like DIC, AKI, acute renal failure (ARF), ARDS, shock and gastrointestinal (GI) bleed.
Objective. The aim of the study was to find out the effect of snakebite envenomation on the major haematological parameters of the body in relation to complications.
Methods. This cross-sectional study was conducted during a period of 18 months. 150 patients were included in the study after obtaining their informed consents. Data collection was done using a proforma. The study also compared clotting time (CT) by capillary tube method and whole blood clotting time at 20 minutes (WBCT20). SPSS software was used for statistical analysis.
Results. Among the people with complications, the majority (52%) of participants had AKI, 26% of them requiring dialysis, 16.7% participants had GI bleed, 11.3% participants had shock and 10% participants had DIC.
Conclusions. A prolonged bleeding time was found to be one of the most helpful haematological parameters in predicting shock and AKI. Clotting time by both capillary tube and WBCT20 methods were comparable in predicting complications.
Objective: The objective of this study was to find the effect of snakebite envenomation on the major haematological parameters of the body.
Material and method: This cross-sectional study was conducted over a period of 18months. A total of 150 patients were included in the study after obtaining informed consent. Data collection was done using a proforma. SPSS software was used for statistical analysis.
Results: Among the people with complications, the majority (52%) of participants had AKI, followed by 26% participants who required Dialysis, 16.7% participants had GI bleed, 11.3% participants had the shock and 10% participants had DIC.
Conclusion: A prolonged bleeding time was found to be one of the most helpful haematological parameters in predicting the shock and AKI.
DIAGNOSTIC UTILITY OF LEUKOCYTE PARAMETERS IN THE PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
Authors: Zhehestovska D. V. , Hrebenyk M. V.
Published: June 2021

Background. Inflammation is one of the key players in acute myocardial infarction (AMI). One of the ways to evaluate it indirectly is to analyze leukocyte parameters of complete blood count (CBC), which is a routine and affordable method of diagnosis. Leukocyte counts can provide additional information about the course, as well as a potential prognosis for complications of AMI. We suggest that the dynamic changes of CBC during the treatment of the patients with AMI may be of value to assess the prognosis of the course of the disease, and therefore require further study.
Objective. The aim of the study to evaluate the diagnostic and prognostic potential of leukocyte indexes of CBC, in particular the levels of leukocytes, lymphocytes, neutrophils and N/L, WBC/MPV, PLT/L ratios in the patients with AMI at the time of hospitalization and on the 7th day of hospital stay.
Methods. The study involved 204 individuals: 152 patients with AMI (Group 1), 30 patients with stable coronary heart disease (Group 2) and 24 healthy volunteers (Group 3). Hemogram parameters and their ratios, in particular the levels of leukocytes, lymphocytes, neutrophils, ESR, as well as the ratios of N/L and PLT/L were studied.
Results. Levels of leukocytes, neutrophils, lymphocytes, as well as N/L, WBC/MPV, MPV/L ratios were significantly higher in the patients with AMI compared to other groups. The best diagnostic value had such indicators as the total number of leukocytes (sensitivity 71.7%, specificity 69.7%, AUC 0.794), the absolute number of granulocytes (sensitivity 81.7%, specificity 77.4%, AUC 0.803), the N/L ratio (sensitivity 75.0%, specificity 71.7%, AUC 0.791) and the WBC/MPV ratio (sensitivity 76.7%, specificity 62.3%, AUC 0.760). The PLT/L ratio calculated on the 7th day of hospital stay correlated with the risk of in-hospital (r=0.369, p=0.002) and 6-month mortality (r=0.338, p=0.004) according to the GRACE score.
Conclusions. Leukocytes, granulocytes, N/L and WBC/MPV ratios had a fairly high diagnostic value for the patients with AMI. Regarding the prognostic potential assessment, only the PLT/L ratio on the 7th day of hospitalization correlated with the risk of in-hospital and 6-month mortality. This proves the importance of assessing CBC parameters not only at the time of hospitalization, but also in the dynamics of AMI.
ДОСЛІДЖЕННЯ АНТОЦІАНІВ ЖИМОЛОСТІ БЛАКИТНОЇ ПЛОДІВ
Authors: Бурлака І. С. , Кисличенко В. С. , Омельченко З. І. , Король В. В.
Published: June 2021

Вступ. Світова наука довела, що плоди і ягоди є одними з найважливіших компонентів структури здорового харчування, оскільки вони накопичують велику кількість біологічно активних речовин, без яких не можливе життя людини. Можливості плодових, ягідних і нетрадиційних садових культур у забезпеченні населення високоякісною продукцією є незамінними для профілактики та лікування багатьох захворювань. Особливе місце серед таких нетрадиційних малопоширених культур займають види роду Lonicera Lindl. Одним з них є жимолость блакитна – плодово-ягідна рослина, яка широко культивується в Україні. Жодний вид жимолостей досі не включено до офіційного реєстру лікарських рослин, до ДФУ, хоча про їх корисні властивості знали ще наші предки. Тому можливість застосування їх у медичній практиці вимагає поглибленого вивчення якісного складу та визначення кількісного вмісту груп біологічно активних речовин.

Мета дослідження – виявити і визначити кількісний вміст антоціанів у жимолості блакитної плодах свіжих та висушених.

Методи дослідження. Ідентифікацію антоціанів проводили загальноприйнятими реакціями і методом тонкошарової хроматографії, їх вміст у жимолості блакитної плодах свіжих та висушених визначали методом абсорбційної спектрофотометрії.

Результати й обговорення.Аналітичні сигнали проведених реакцій ідентифікації свідчили про наявність антоціанів у жимолості блакитної плодах свіжих і висушених.Методом тонкошарової хроматографії було виявлено наявність ціанідин-3,5-диглюкозиду і ціанідин-3-О-глюкозиду. Вміст антоціанів у жимолості блакитної плодах свіжих становив (0,42±0,03) %, у висушених – (0,31±0,02) % у перерахунку на ціанідин-3-O-глюкозид. З метою стандартизації сировини можна запропонувати нормований показник – вміст антоціанів у жимолості блакитної плодах не менше 0,35 % у перерахунку на ціанідин-3-O-глюкозид і суху сировину.

Висновки. Загальноприйнятими реакціями і методом тонкошарової хроматографії доведено наявність антоціанів у жимолості блакитної плодах. Методом абсорбційної спектрофотометрії в жимолості блакитної плодах свіжих і висушених визначено вміст антоціанів. Результати досліджень будуть використані при розробці параметрів стандартизації сировини. Жимолості блакитної плоди можна використовувати для розробки й одержання лікарських субстанцій, функціональних харчових продуктів комплексної вітамінно-мінеральної дії.
Música, sons e dissensos: a potência poética feminina nas ruas do Rio
Authors: Fernandes Cíntia Sanmartin , Herschmann Micaeal
Published: June 2021

Nesse artigo busca-se repensar a vitalidade e capacidade movente das músicas e sons rimados na cena do slam e do hip hop feminino, que potencializam estética e politicamente experiências artivistas na cidade do Rio de Janeiro, elaborando territorialidades e dissensos significativos. Parte-se do pressuposto de que esses atores vêm descontruindo os discursos e as práticas associadas aos gêneros, os quais são naturalizados no cotidiano, especialmente o de mulheres pobres e negras do país. Assim, analisa-se a atuação dessas redes que se engajam no “mundo da rima feminina carioca” – que participam das Batalha das Musas e do Slam das Minas –, os quais vêm não só construindo heterotopias potentes, mas também reinserindo várias temáticas na pauta do dia, tais como: cidadania, gênero, pós-gênero, racismo, machismo, heteronormatividade e violência.
Para una crítica de la cultura y la comunicación: una aproximación a la perspectiva de la comunicación-mundo de Armand Mattelart
Authors: Zarowsky Mariano
Published: June 2021

La noción de comunicación-mundo condensa el proyecto intelectual que Armand Mattelart forjó en Francia hacia fines de los años ochenta del siglo XX y desarrolló con creatividad y constancia en la década del noventa. Este proyecto se presenta y despliega en su trilogía de la comunicación-mundo: La Communication-monde (1992); L’Invention de la communication (1994); Histoire de l’utopie planétarie (1999). Desde mediados de los años ochenta se extendía en Francia un discurso que hacía de la comunicación un valor explicativo de lo social. Situar la posición teórica de Mattelart en este contexto nos permitirá dar cuenta de las condiciones de emergencia de su reflexión, pero también de la singularidad y productividad de su perspectiva para entender la organización social contemporánea a través de la crítica de la cultura y la comunicación.
Pionera: los aportes de Michèle Mattelart al campo comunicacional
Authors: Heram Yamila , Gándara Santiago
Published: June 2021

En los balances y retrospectivas del campo comunicacional latinoamericano las obras más nombradas refieren a los padres fundadores. Esto advierte de un hecho evidente, los aportes de las mujeres ocupan un lugar periférico. Si bien Michèle Mattelaert ha sido una de las pioneras que, en este contexto desigual, más reconocimiento ha obtenido, y sin desconocer que la trayectoria de Michèle y Armand ha sido en gran parte compartida y de mutua influencia y diálogo, este artículo se centra en caracterizar el recorrido intelectual de Michèle y detenernos específicamente en una lectura de los trabajos de su primera etapa (1963-1973), es decir aquellos escritos que han marcado sus aportes pioneros al campo comunicacional latinoamericano.
Igreja eletrônica, religiosidade midiática, religiosidade midiatizada: conceitos para pensar as relações entre mídia e religião
Authors: Sousa Marco Túlio de
Published: June 2021

O crescente número de pesquisas sobre mídia e religião tem favorecido a emergência de um conjunto diverso de olhares sobre o fenômeno, o que se reflete em diferentes metodologias, teorias e conceitos. Este artigo objetiva discutir conceitos recorrentes em trabalhos de pesquisadores desta área, sobretudo no Brasil, e indicar de que modo nos ajudam a entender aspectos dessa problemática, bem como possíveis limitações. Assim, por meio de revisão bibliográfica, reflete-se sobre a produtividade de conceitos gerais como igreja eletrônica, religiosidade midiática, religiosidade midiatizada para pensar as transformações da religião na contemporaneidade nas suas interconexões com a mídia.
As revoluções das mídias: as transformações da era digital à luz do surgimento da imprensa
Authors: Schmitt Juliana
Published: June 2021

Esse texto é uma resenha do livro A Europa de Gutenberg: O Livro e a Invenção da Modernidade Ocidental (Séculos XIII-XVI), do historiador francês Frédéric Barbier, lançado na França em 2006 e no Brasil em 2018, em tradução publicada pela Edusp. O autor traça um panorama histórico do surgimento da prensa de tipos móveis, atentando para os processos sociais, econômicos e culturais que o antecedem e o sucedem, cobrindo, portanto, mais de três séculos. Com essa análise, sua proposta é elaborar um paralelo entre a revolução causada pela imprensa e a atual revolução digital, suas causas e consequências.
O paradoxo da ideologia
Authors: Silva Juremir Machado da
Published: June 2021

Este texto examina definições de ideologia de autores clássicos e um paradoxo: se tudo é ideológico e se ideologia tudo condiciona, como é possível compreender o seu funcionamento e fazer a sua negação?
Movement Planning Determines Sensory Suppression: An Event-related Potential Study
Authors: Jack Bradley N. , Chilver Miranda R. , Vickery Richard M. , Birznieks Ingvars , Krstanoska-Blazeska Klimentina , Whitford Thomas J. , Griffiths Oren
Published: June 2021

Sensory suppression refers to the phenomenon that sensory input generated by our own actions, such as moving a finger to press a button to hear a tone, elicits smaller neural responses than sensory input generated by external agents. This observation is usually explained via the internal forward model in which an efference copy of the motor command is used to compute a corollary discharge, which acts to suppress sensory input. However, because moving a finger to press a button is accompanied by neural processes involved in preparing and performing the action, it is unclear whether sensory suppression is the result of movement planning, movement execution, or both. To investigate this, in two experiments, we compared ERPs to self-generated tones that were produced by voluntary, semivoluntary, or involuntary button-presses, with externally generated tones that were produced by a computer. In Experiment 1, the semivoluntary and involuntary button-presses were initiated by the participant or experimenter, respectively, by electrically stimulating the median nerve in the participant's forearm, and in Experiment 2, by applying manual force to the participant's finger. We found that tones produced by voluntary button-presses elicited a smaller N1 component of the ERP than externally generated tones. This is known as N1-suppression. However, tones produced by semivoluntary and involuntary button-presses did not yield significant N1-suppression. We also found that the magnitude of N1-suppression linearly decreased across the voluntary, semivoluntary, and involuntary conditions. These results suggest that movement planning is a necessary condition for producing sensory suppression. We conclude that the most parsimonious account of sensory suppression is the internal forward model.