bluuebunny/crossref_metadata_2025 huggingface dataset:
Right to Food Policies, Justice and Sovereignty in Nigeria
Authors:   University of Calabar, Effiong John
Published: October 2024

This study assessed the right to food policies, justice and sovereignty in Nigeria. The main areas of concentration were: introduction, meaning of food policy, some food policies in Nigeria, types of policies, audit of right to food policies in Nigeria, past policy articulations (1900 – 1999), food policy articulation and policy thrust in 2003, food policy legislations, sovereignty of food and agricultural development among many others. The study indicated that food policy is a public declaration that conveys the decisions to pursue a specific course of action aimed at improving food production practices, ensuring output growth and the overall development of the food sector. Some food policies in Nigeria are; food crop production policy, livestock production policy, food commodity storage policy among others. The study identified three types of polices namely; position declaration, policy statements and discussion papers. Past policy articulations are: Timber/non timber policy 1937, food policy 1946 and food policy for the western region 1952. Some policy legislations were identified, namely: adulteration of produce ordinance No.67 of 1917; 29 of 1920, 8th November 1917, Weight and measurements Act No. 32 of 1974 to June 1975 and River Basin Development Authorities Act No.35 of 1st October, 1986. Some inventory of right to food sovereignty strategies in Nigeria includes: Sovereignty strategy formulations, commodity boards, National Accelerated Food Production Project (NAFPP), National Livestock Development Project (NLDP), Operation Feed the Nation (OFN) and Green Revolution among very many others. One major problem of food policy implementation is lack of a well-defined programme. In conclusion, Right to Food Policy, Justice and Sovereignty Implementation means money spent, laws enforced, employees hired, plan of action formulated and carried out successfully for the development of the Nigerian food sub-sector. But the problem with Nigerian food policies is the structure among which is the absence of central coordinating members. Also, the study recommended that there is the need for government to set institutions that will monitor the planning and execution of food polices projects. Key words: Agricultural Development, Food, Justice, Legislations, Nigeria, Policies, Rights, Sovereignty
Food Sovereignty and Food Rights
Authors:   African Journal of Food, Agriculture, Nutrition and Development, Oniang'o Ruth
Published: October 2024

What is food sovereignty? What is food rights? In the recent past I have had the privilege to attend two amazing events here in Nairobi. One, the graduation of the third cohort of African Food Fellows started by scholars at Wageningen University in the Netherlands, and the other at the World Agroforestry Centre's Gigiri campus in Nairobi as African Plant Breeding Academy Fellows graduated the third cohort. My one common observation is that we have amazing programs elevating brilliant young Africans to a level where they can confidently address issues of hunger, malnutrition and poverty. African food fellows are made to provide leadership in this sector and only do so once they have been equipped with the appropriate tools and knowledge. The plant breeders are equipped with new skills in breeding that enable them to expand their performance and work. In both situations and I am sure in many more, governance and policies still come out as real concerns. In all this I see young people who are passionate about making a difference in their countries and on the continent, about impacting the ground and wanting to ensure food rights for the vulnerable amongst us. These young people will understand that food sovereignty means us valuing and protecting our food culture and food sources, and providing for the vulnerable: elderly, the disabled, and the income-less. The young people need to be passionate about food rights and hopefully will be in decision making positions where they ensure that nobody ever goes to bed hungry. They will do so because unlike now, they will understand the issues. What we need now is help for more capacity building programs.
Performance and Perception Disparities in Blended Learning Across Varied Vocational Academic Backgrounds
Authors: Cao Yujie , Abdul Aziz Azhan , Mohd Arshard Wan Nur Rukiah
Published: October 2024

With rising popularity of vocational education in China, the study investigates how academic backgrounds influence vocational students’ perceptions and learning outcomes in a blended SketchUp course, guided by Blended Learning framework and Technology Acceptance Model (TAM). Quantitative data from 71 undergraduate and 71 junior college interior architecture students was analyzed using statistical methods, including descriptive statistics, correlation analysis, and t-tests. The analysis showed no significant differences between academic groups in academic achievements, but differences in several perceptions, suggesting equitable learning experiences in the blended course. Tutorial videos may have contributed to personalized pacing, reducing variations among learners. Applying TAM to analyze student acceptance and engagement further enriches understanding of how academic backgrounds impact the utilization of educational technologies. These findings emphasized the potential of well-designed blended learning models for inclusive education. Results verified and enriched blended learning theory regarding differentiated instructions and online personalization to foster equitable, quality education, addressing diverse learning needs.
Challenges in the diagnostics of mantle cell lymphoma in an elderly comorbid patient
Authors: Binyakovskiy Rostislav V. , Borisovskaya Svetlana V. , Zaharov Oleg D. , Kiselev Dmitry G. , Lepkov Sergey V. , Melekhov Alexander V. , Nikitin Igor G. , Salikov Alexander V.
Published: October 2024

We present a case of a rare lymphoproliferative disease diagnosed while differentiating between the causes of exudative-constrictive pericarditis.
An 83-year old man was hospitalized with shortness of breath, edema and newly diagnosed atrial fibrillation (AF). Initially, the signs and symptoms were interpreted as manifestations of heart failure due to old myocardial infarction, arterial hypertension and AF. However, no significant systolic or diastolic dysfunction of the left ventricle and valve disease were identified and natriuretic peptide level was normal. Despite treatment, dyspnea and edema persisted, and pleural effusion (requiring drainage) and pericardial effusion increased. Repeated echocardiography showed signs of exudative-constrictive pericarditis. We consequently excluded the infectious (tuberculosis) and non-infectious (electrolyte disorders, hypothyroidism, solid tumors) etiologies of effusion. Taking into account the long-standing mediastinal lymphadenopathy (the patient had been previously examined, but the cause not identified), anemia, episodes of low-grade fever, weight loss, and polyneuropathy, a lymphoproliferative disease was suspected. Serum protein electrophoresis identified an M spike in the gamma globulin region. Immunophenotyping of peripheral blood lymphocytes and immunohistochemical examination of bone marrow confirmed the diagnosis of mantle cell lymphoma. The patient was referred for specialized treatment. At 5 months of the follow-up, the therapy was successful, the patient was stable with no cardiac complaints, no edema, and no new AF episodes.
The case demonstrates the need to strictly follow differential diagnostic algorithms to identify the causes of nonspecific symptoms beyond one medical specialty.
Decoding Variation among the Phenolic Composition and Antioxidant Properties of Some Finger Millet [Eleusine coracana (L.) Gaertn.] Landraces Grown in Maharashtra, India
Authors: Kazi Tahsin , Khyade Mahendra , Laware Shankar , Auti Sanjay
Published: October 2024

Background: The profiles of phenolic compounds and antioxidant capacities of ten finger millet landraces harvested from the northern Western Ghats of Maharashtra were investigated. Methods: The antioxidant activity of methanol extracts of ten landraces were assessed using H2O2, FRAP and Phosphomolybdenum assays. Result: Results of the H2O2 scavenging assay exhibit variation in their inhibition activity (59 -90.12 %). The highest H2O2 scavenging activity was shown by T1, followed by T2, T3, T5, T8, T10 and T29 (90.12, 82, 79.8, 82.9, 79 and 85.78 respectively) when compared the control sample T had significantly lower activity (55.87%). While the reducing power was in the range of 1.02-1.76 mM of Fe (II)/gm and the reducing capacity was in the range of 73.86-158.71 equivalents of ascorbic acid in µg/gm of extract. The highest reducing power was shown by T2, T15 and T8 as 1.98, 1.94 and 1.89 mM of Fe (II)/gm respectively; while lower values were recorded in T19 (0.89 mM of Fe (II)/gm) and T1 (1.02 mM of Fe (II)/gm). The total antioxidant activity of the methanolic extract was calculated as ascorbic acid equivalents (AAE) per gram. Based on the results, T2, T5, T8 and T10 had a high reducing potential (158.71, 143.2, 149.5 and 152.65 AAE of a sample, respectively) with reducing capacities ranging from 73.86 to 158.71 AAE. A total of seventeen phenolic compounds were identified in the extracts including seven ûavonoids, with catechin, Iso –orientin and Iso-vitexin being the predominant flavonoids. Ten phenolic compounds were identified in the extracts, with p-hydroxybenzoic acid, genistic acid and gaillic acid being the predominant ones. In conclusion, based on the antiradical activities, the landraces T2, T5, T8, T10 and T29 could be potential cultivars and certainly effective sources of natural antioxidants for applications in the food and pharmaceutical industries.
Sociodemographic and Mental Health Factors Associated with Obesity in Resettled Refugees in Syracuse, New York
Authors: Mutambudzi Miriam , Sharma Akritee , Sous Waseem , Shaw Andrea V. , Heffernan Kevin S.
Published: October 2024

Introduction

Resettled refugees have been exposed to stressful and life-threatening events preresettlement and are among the most marginalized and vulnerable groups in society. Postresettlement, they face challenges when assimilating to an unfamiliar host country, which renders them vulnerable to adverse health outcomes including obesity, a major public health burden. This study was conducted to examine the association of mental health and sociodemographic factors, including language proficiency and educational attainment, with obesity in first-generation resettled refugees.

Methods

We used data from electronic health records from the Adult Ambulatory Medicine Clinic of the State University of New York Upstate, Syracuse, NY. The probability of being overweight and obese (class I and class II) relative to normal weight was estimated using fully adjusted multinomial logistic regression models with relative risk ratios (RRRs).

Findings

Relative to male refugees, female refugees were more likely to have class I obesity (RRR=1.83; 95% confidence interval [CI]=1.19, 2.80) and class II obesity (RRR=4.07; 95% CI=2.41, 6.87). Limited English proficiency increased the risk of being overweight (RRR=2.02; 95% CI=1.29, 3.17) and having class II obesity (RRR=2.14, 95% CI=1.20, 3.81). A clinical mental health diagnosis increased the risk of class I (RRR=2.00; 95% CI=1.35, 2.96) and class II (RRR=1.76; 95% CI=1.15, 2.71) obesity. Having no formal education was associated with decreased risk of class II obesity (RRR=0.42; 95% CI=0.19, 0.90).

Discussion

Obesity prevalence and subsequent related morbidity continue to be major public health burdens in vulnerable, often underserved populations in the United States. Further investigation into social determinants of obesity in refugees in a community setting that captures the unique experiences of heterogenous refugee groups outside the clinical setting is warranted.
Fostering Resilience in Palestinian Higher Education: Strategies for Effective Management and Progressive Transformation
Authors: Diab Al-Khansaa
Published: October 2024

This research explores how Palestinian universities have shown resilience and implemented strategies to overcome challenges caused by the occupation. It delves into the leadership-led reforms in engineering, law, and medicine within these institutions through in-depth interviews with program deans. The study highlights how faculty members adjust curricula, teaching techniques, and program frameworks to tackle obstacles and address changing needs. Key strategies identified for resilience include flexibility, investment in staff development, fostering international partnerships, and effective management practices. Progress in achieving gender equality and the successful global careers of graduates are noted as signs of effective management. By embracing pedagogy and community involvement, these universities demonstrate the power of higher education in conflict zones. They navigate adversity by encouraging critical thinking and social accountability, showcasing the potential for education to drive change during times of conflict. The insights gained from this research offer lessons for institutions confronting similar sociopolitical challenges while emphasizing the significance of resilience, adaptability, and effective management during crises.
A clinical case of scapula fragment fracture with dislocation of fragments
Authors: Khorak K. I. , Kogan P. G. , Parfeev D. G. , Dzhafarov V. T. , Morozov A. M. , Piskareva M. E.
Published: October 2024

Relevance. According to statistical data, fractures of the scapula are quite rare, accounting for approximately 3-5% of all shoulder girdle fractures and less than 1% of the total number of fractures. Because of the high-energy nature of scapula fractures, 80% to 95% of cases are associated with additional traumatic injuries. The aim: to analyze the technique of performing surgical intervention in a fragment fracture of the right scapula with displacement of the fragments on the example of a clinical case. Object and methods. Patient G., 21 years old, on 12.10.2023 applied to the trauma center № 114 after a wind-driven tree fell on his right forearm area. A fracture of the right scapula with displacement of the fragments was detected, the patient was referred to the emergency room of the R.R. Vreden Research and Development Center for further examination and treatment. On admission to the department, the patient's right supraclavicular region was longer than the left one, the right supraclavicular region at the acromial end was swollen and painful, without visible deformity. Results. The study presents traumatologic pathology, namely, fractures of the articular and clavicular processes of the scapula with displacement of the fragments, as well as fracture of the acromial process of the scapula with minimal displacement of the fragments and cranial subluxation of the acromial end of the clavicle. The causes, diagnostic methods and surgical treatment of this pathology are described. Conclusions. Due to the growing amount of data on satisfactory postoperative results in patients with scapula fractures, there is still interest in surgical trends in the treatment of these patients. However, it is worth remembering that postoperative complications after repositioning and fixation of bone fragments continue to be an urgent problem.
The feasibility of pathogenetic therapy for chronic viral hepatitis C in adult HIV-infected patients
Authors: Bun'kova E. B. , Bileva N. A. , Sinel'nikov M. I. , Bilev A. E.
Published: October 2024

In the third decade of the XXI century, HIV infection and viral hepatitis C remain urgent problems of modern medicine. Only in the Russian Federation in 2023, more than 1.6 million HIV-infected people and about 2 million patients with chronic viral hepatitis C are registered. Patients with a combined course of these diseases are of particular concern. However, insufficient coverage of etiotropic therapy for patients with chronic viral hepatitis C due to its high cost leaves pathogenetic therapy as the only available method of treatment for many of them. Material and Methods. Clinical data of patients hospitalized in the day hospital of the state budgetary health care institution "Samara Regional Clinical Center for AIDS Prevention and Control" were used. Physical, virological, immunological, biochemical and general clinical methods, elastometry of liver tissue were used for examination of hospitalized patients. Statistical processing of the results was performed using the application program "Statgrarhics Plus for Windows". Pathogenetic therapy was carried out in a two-week course in accordance with the "Recommendations for the diagnosis and treatment of adult patients with hepatitis C" (2013) and included (along with protective regime and therapeutic nutrition) the use of detoxification and metabolic therapy. Antiretroviral therapy with 3–4 drugs was carried out in 68% of the patients. Results. It was shown that the prescribed course of pathogenetic therapy of chronic viral hepatitis C did not have the expected effectiveness in the majority of patients referred for treatment according to the dynamics of changes in the values of "liver tests", despite the fact that the "right subcostal syndrome" was eliminated in 75.7% of persons with stage 3 and 66.7% with stages 4A and 4B of HIV infection. Statistical studies of the relationship (linear, rank and canonical) did not reveal its presence between the results of the conducted treatment and the complex of initial clinical and clinicallaboratory data obtained during hospitalization of the examined persons. Discussion. The presence of cytolysis syndrome and "right subcostal syndrome" is not a valid criterion for referral to a two-week course of pathogenetic therapy of chronic viral hepatitis C in order to obtain a positive result in the majority of patients with stages 3, 4A and 4B of HIV infection. Other baseline data (virologic and immunologic indices, degree of liver tissue fibrosis, indices of general and biochemical blood analysis) had no reliable correlation with the results of treatment, which did not allow their use for predicting the effectiveness of the prescribed treatment. Antiretroviral therapy was not associated with the results of pathogenetic therapy of chronic viral hepatitis C according to the indicators of cytolysis syndrome and "right subcostal syndrome", despite the fact that most of the prescribed drugs had a hepatotoxic effect.
A modern look at the methods of radiation diagnosis of osteoporosis
Authors: Vel'ma K. M. , Kalashnikova E. A. , Dovgyallo Yu. V.
Published: October 2024

Osteoporosis, according to the World Health Organization, ranks fourth among the causes of death and disability after cardiovascular, oncological diseases and diabetes mellitus. Among residents of Russia over the age of 50, osteoporosis occurs in about one in three women and one in four men. This pathology has a high social significance, since it often causes a high level of disability of the adult population. From the point of view of reducing the incidence of mortality and disability of the able-bodied population from osteoporosis, the problem of its prevention and early diagnosis, including using radiation research methods, is paramount. Information on this issue is quite scattered today, requires systematization and generalization. The study and analysis of the available literature on the possibilities of radiation diagnosis of osteoporotic changes were carried out. Summarizing the available information on the radiation diagnosis of osteoporosis, we should talk about the need to introduce a preclinical examination for this pathology, since there is data on the results of opportunistic screening in some groups of patients. The vast majority of such cases are asymptomatic, which once again confirms the need for a preventive approach to this problem. Taking into account the variety of existing methods for diagnosing osteoporosis in the early stages, the most reliable, with some of its disadvantages (the presence of radiation exposure, the high cost of equipment), are still dual-energy X-ray densitometry and quantitative computed tomography, the analogue of which, with limited resources to provide equipment for medical institutions, is ultrasound densitometry.
Dynamics of disability in the adult population of the Astrakhan region due to diseases of the cardiovascular system over 2016–2022
Authors: Starodubova E. B. , Chernysheva E. N. , Svetlichkina A. A. , Svinskayte V. V.
Published: October 2024

In the structure of primary disability pathologies of the cardiovascular system hold second position in the Astrakhan region. The article presents statistical indicators of primary and repeated disability of the population in the Astrakhan region due to diseases of the cardiovascular system from 2016 to 2022. Analysis of the structure of primary disability indicates that among the study population in the Astrakhan region there was a higher proportion of disabled people of group III. Elderly disabled people are in first place in the age structure of primary disability due to diseases of the cardiovascular system.
The influence of work activity on the duration and quality of life of older people (analytical review)
Authors: Shabalin V. N. , Shatokhina S. N.
Published: October 2024

The problems of optimal participation in labor activity of people of older age groups are considered. The dynamics of demographic aging are characterized by duality: against the background of chronological aging, biological rejuvenation of the world's population occurs, which significantly increases human potential. We must move away from erroneous ideas about older age as a period of “sluggish living”; on the contrary, this age provides a person with the opportunity to live a highly productive life. It can be reasonably argued that the older generation today has become more mobile and socially active. Global trends in the transformation of the labor market demonstrate a gradual shift in the employment structure towards older ages. Labor is the basis for the social self-realization of older people and a condition for prolonging active life. The average life expectancy of pensioners who remain active is significantly higher than those who have stopped working. Labor is the most powerful geroprotector! Protecting the physiological state of intelligence in old age is the main task of gerontology and geriatrics. We need to be very critical of current ideas about the degradation of intelligence in old age. The process of intellectual development of a person of mental labor is fundamentally limitless - this is the main way of his existence as an individual. The level of education has a significant impact on life expectancy. People with higher levels of education have lower mortality rates and longer life expectancy. The dominant models of the social status of older people forcefully pushes the elderly person out into “well-deserved rest.” The introduction of a mandatory retirement (“disabled”) age for everyone means that the legislator declares the experience accumulated by older people to have lost social significance. This attitude is a factor in the growth of social tension and impedes the formation of social cohesion, gives rise to a social trend of age discrimination - “ageism”, which manifests itself, in particular,in difficulties in finding a job and in the reduced level of wages for older people. As a result, over the past decade, the number of working pensioners in Russia and the duration of their period of work after retirement have decreased significantly. It is necessary to create a long-term doctrine of the work activity of older people.
Main trends in providing medical personnel to the state healthcare system of the Russian Federation
Authors: Agamov Z. Kh. , Aziattseva E. V. , Doronshoeva D. A. , Savzikhanov R. T.
Published: October 2024

The purpose of this study is to analyze trends in the provision of medical personnel to the state health care system during the implementation of state programs and national projects in the field of health care. Materials and methods. Statistical collections of the Ministry of Health of Russia for 2012–2023, regulatory legal acts, passport of national project. Methods of descriptive statistics and analytical were used. Results. A reduction in indicators of the supply of doctors, paramedical personnel and the ratio of doctor/nursing medical personnel and a discrepancy between their target values established in state programs and national projects for the development of healthcare was revealed. Differences in the values of target indicators of state programs and national projects have been identified. Conclusion. The need to take urgent measures to eliminate the reduction in the supply of medical personnel has been identified. Differences in the dynamics of staffing indicators indicate the heterogeneity of the level of development of regions and their preparedness for events within the framework of state programs and national projects to achieve target indicators. Measures are needed to eliminate territorial imbalances, as well as to search for mechanisms to equalize differences between the constituent entities of the Russian Federation. Differences in the values of indicators for achieving the goals of state programs and national projects complicate their assessment and determine the need to form a hierarchy of state programs and national projects, as well as the development of scientifically based target indicators, taking into account regional characteristics and the needs of the population for medical care.
Features of dissomnia and cognitive impairments in chronic cerebral ischemia due to diabetes mellitus type 2
Authors: Kotsenko Yu. I.
Published: October 2024

Introduction. Currently, diabetes mellitus occupies a leading position in terms of prevalence, disability, mortality and it is a medical and social problem. Microvascular and macrovascular diabetic complications negatively affect the quality and duration of sleep with detrimental effects on metabolism and weight regulation. The cognitive sphere is more impaired in type 2 diabetes mellitus in the form of a decrease in the speed of reaction to external stimuli and the ability to concentrate for a long time, so thinking becomes slower, and clinically significant cognitive impairments leads to work and social maladaptation and a decrease in adequate glycemic control. Aim of the study: to study the nature of diagnosed cognitive impairments and variants of dissomnias in chronic cerebral ischemia and to evaluate the features of identified dissomnias in the development of early dementia in type 2 diabetes mellitus. Object and methods. During the period from 2017 to 2023, 207 patients with chronic cerebral ischemia and neurological deficits of varying severity were examined. All patients underwent a comprehensive clinical and neurological examination using specialized scales to study the cognitive sphere and sleep level, laboratory and instrumental methods of examination. The study applied non-inclusion, inclusion and exclusion criteria and selected 147 patients with chronic cerebral ischemia and type 2 diabetes mellitus. The data has been processed statistically. Results. Cognitive impairments (95,1 ± 2,4%) and dyssomnia (88,9 ± 3,5%) develop in patients with type 2 diabetes mellitus with chronic cerebral ischemia, and their combination is significant (p < 0,05) prevailed (82,7 ± 4,2%) with dysmetabolic signs. At the same time, moderate (43,2 ± 5,5%) and severe (34,6 ± 5,3%) cognitive disorders with moderate dyssomnia (63,0 ± 5,4%) and increased sleepiness (64,2 ± 5,3%) with episodes of obstructive sleep apnea (16,0 ± 4,1%) and narcolepsy (6,2 ± 2,7%) compared with patients without type 2 diabetes mellitus (p < 0,05). Conclusions. The presence of type 2 diabetes mellitus increased the risk of developing dyssomnia and cognitive disorders, and the identification of dyssomnia led to an increased chance of a deterioration in the intellectual-mnestic level to the degree of moderate and severe impairments. Neuropsychological testing in combination with dyssomnia questionnaires and quantitative assessment of the severity of cognitive dysfunction is absolutely necessary.
Bleaching efficacy, decomposition rate and pH of experimental bleaching gels incorporating bioactive materials
Authors: Coelho Camila Siqueira Silva , Rigo Izabele Gemeli , Dascanio Rafael , Souza Marina Trevelin , Zanotto Edgar Dutra , Tabchoury Cinthia Pereira Machado , Cavalli Vanessa
Published: October 2024

Aim: To evaluate the bleaching efficacy, decomposition rate, and pH of experimental gels containing 35% hydrogen peroxide (HP) and different concentrations of 45S5-bioglass (BG) or Biosilicate® (BS). Methods: Bovine enamel/dentin blocks (n=10) were allocated into the groups HP_BG or HP_BS (2.5, 5, 7.5 and 10 wt%) and HP (35% HP – positive control). The blocks were submitted to three sessions of 40 min and 7-day intervals. During the interval, the blocks were kept in artificial saliva at 37ºC. Color change (ΔE00) and whiteness index change (ΔWID) were determined after staining with black tea (T1) and 24 h after the 3rd bleaching session (T2). HP decomposition rate (%) and pH were evaluated for 40 min. Two-way ANOVA and Tukey analyzed ΔE00 and ΔWID data, while the Kruskal-Wallis test determined the decomposition rate and pH of the gels. Results: There were no differences in ΔE00 and ΔWID among the experimental bleaching gels containing BG or BS and 35% HP (p > 0.05), but BG and BS gels displayed lower HP concentration than 35% HP, regardless of the bioactive material concentration (p < 0.05). The experimental BG and BS gels exhibited alkaline pH (ranging from 9.28 to 9.82), which was higher than that of 35% HP (p < 0.05). But regardless of the gel, all kept the pH values stable for 40 min. Conclusion: The experimental gels containing BG and BS did not hamper the 35% HP bleaching efficacy. Moreover, BG or BS gels decreased the hydrogen peroxide concentration and exhibited alkaline pH values.
Design and evaluation of an active vineyard heating system to simulate temperature increase in the context of climate change
Authors: Cirrincione Miguel Ángel , Arancibia Celeste , Dominguez Deolindo L. E. , Malovini Emiliano Jesús , Martínez Liliana Estela
Published: October 2024

The current study introduces an innovative direct and active heating system designed for precise temperature control in vineyards. This system serves as a valuable tool for investigating the influence of climate change on grapevine physiology and, consequently, the characteristics of the resulting wine. The research took place in an experimental vineyard located in Mendoza, Argentina, with V. vinifera cvs. trained to a vertical shoot positioning trellis system over two consecutive growing seasons. The system design utilized electric hot water tanks and polypropylene pipes attached to the foliage catch wires. Over two growing seasons, the system consistently elevated the ambient air temperatures within the canopy by 2.5 ± 0.12 °C compared to the control group. This temperature increase emulated the temperature projections for Mendoza as forecasted by the IPCC by the end of this century. The system displayed heating uniformity, as evidenced by the absence of both vertical and horizontal temperature gradients. Additionally, the significant variation in mean daytime and night-time temperatures between the control and heated treatments highlighted the effectiveness of the system in modifying temperature conditions on a diurnal basis. The heated treatment applied with this system proved to have an effective biological impact on the physiology of grapevines. In both seasons, plants under the heated treatment advanced their bud break and harvest dates. The study showed a significant growth enhancement in the heated treatment, with apical shoots extending significantly longer than those in the control treatment. Additionally, the total soluble solids content increased in the heating treatment, while yield decreased, for both experimental seasons. These results illustrate the robust performance of the system throughout the entire growth period, regardless of fluctuations in atmospheric conditions. This study establishes a new foundation for future research on grapevine responses to climate change. It also opens the door to the implementation of effective adaptation strategies in vineyards, promising a more resilient and adaptable future for grape cultivation.
Gravity and Riemann Hypothesis
Authors: Shi Jun Ze
Published: October 2024

Based on the understanding of relativity and quantum mechanics, this paper demonstrates that gravity is the result of spatial shape and dimension changes. The concept of space as dimension is expounded, and the difference between gravitational field space and material space is distinguished. The reason why the photon moves in space at a constant speed of c is explained. The concept of positive and negative energy is discussed, and the microscopic performance of positive energy as compression space and negative energy as stretching space is explained. Trying to understand increases the understanding of micro-uncertainty in dimensions. It explains how matter generates new dimensions in the process of collision, especially through elastic collision to generate different dimensions and energy forms. The hierarchical control of dimension formation and how to achieve dimension balance are mentioned. The influence of dimension on life is discussed, especially how the change of dimension affects the basic properties of matter. proposed four forces that are most easily observed in any dimensional matter and explained their relationship to dimensional change. Through the mapping phenomenon of memory and reality, the role of residual energy is discussed. The concepts of π and e in mathematics are used to explain the process of dimension formation and energy transmission. The application of Riemann hypothesis and in understanding physical phenomena is mentioned. The imbalance between positive energy and negative energy is emphasized. It explains why quantum is both a particle and a wave, and how this characteristic is related to the change of dimension. The only possibility to explain the universe before the change from the vibration. Explain the reason of path integral, so as to judge whether there is superposition state. Explain why there is a minimum unit of radiation energy and it shows a multiple relationship. It is proposed that the time in quantum motion is only a parameter, which further strengthens the relationship between gravity and spatial shape. Explain how gravity causes the universe to expand. By combining mathematics, physics and philosophical thinking, the article reveals the complex and subtle mechanisms hidden behind nature.
Sociocultural Aspects and Isolation of Streptococcus spp. from Dental Biofilm: A Comparison of Patients in Public Health and Private Dental Practices
Authors: Eça Edmone Campos de , Oliveira Mariana Ely Araujo , Oliveira Valdineia Dias , Ferraz Marcelo Inácio Ferreira , Carvalho Luciana Debortoli de , Conceição Aline Oliveira da
Published: October 2024

The different sociocultural context and lifestyle may influence oral health. To evaluate the interference of these factors, we conducted a quantitative-qualitative cross-sectional study. The research was carried out in a private dental office, in an urban area, and in the Family Health Unit (USF), in a rural area. Fifty patients of each location participated on the research. A semi-structured questionnaire covering sociocultural profile, oral hygiene habits, drug consumption, use of medicinal plants, and antibiotics usage was applied. Also, laboratory tests to evaluate the tendency to have dental decay and Streptococcus sp colony counting was performed. There was no significant difference between patients in the two groups regarding gender, race, marital status, type of residence, number of residents in the same household, and type of employment. Private clinic participants were more prone to consuming alcohol and/or cigarettes and reported to brush the teeth more often. There was no association between salivary acidity and higher biofilm bacterial density. The usage of medicinal plants was more evident in the public service. Data presented here revealed that social inequality between private and public dental assistance are greater from the point of view of investment in public health for the population with difficult access and not from cultural or educational level diversity.
Empowering Nanostores for Competitiveness and Sustainable Neighbourhoods in Emergent Countries: A GenAI Strategy Ideation Process
Authors: Salinas-Navarro David Ernesto , Vilalta-Perdomo Eliseo , Michel-Villarreal Rosario
Published: October 2024

This exploratory study investigates the use of Generative Artificial Intelligence (GenAI) tools in developing strategy practices for nanostores — i.e., small independent grocery retailers — to enhance their competitiveness while contributing to community sustainability. Nanostores, particularly in emerging countries, face intense competition and rapidly changing trends. By leveraging their proximity to consumers in neighbourhoods, these stores adopt various strategies, such as offering complementary services, integrating technology, and adapting business models. While existing literature highlights the broader economic, social, and environmental roles of nanostores, there is limited comprehensive research on how they may simultaneously contribute to their competitiveness and communities’ sustainability. This study employs a 'thing ethnography' approach, using GenAI tools —i.e., ChatGPT 3.5 and Microsoft Copilot— to explore potential strategy practices for these shops, and reflect on their possible use for strategy ideation and implementation. Key findings suggest that prioritising local sourcing, understanding local preferences, flexible inventory management, efficient retail operations, in-store sustainable practices, promoting healthy lifestyles, and diverse community engagement are crucial for success. However, the study also acknowledges the limitations of GenAI tools, including possible bias and the need for result validation. By aligning with these evolving requirements, nanostores can strive in neighbourhoods and decisively promote sustainable communities.
ABA and Melatonin: Players on the Same Field?
Authors: Bychkov Ivan A. , Kudryakova Natalia V. , Pojidaeva Elena S. , Doroshenko Anastasia S. , Shitikova Victoria , Kusnetsov Victor V.
Published: October 2024

In plants, melatonin (MT) and abscisic acid (ABA) are conventionally treated as molecules mitigating stress responses. To understand the mechanisms of ABA–MT interplay, we examined the effects of ABA and MT treatment in loss-of-function ABA and MT mutants exposed to high light (HL) stress. ABA constantly suppressed ASMT encoding N-acetylserotonin methyltransferase in the context of differential responses of other MT biosynthesis genes in both wild type (WT) and mutants. However, this response was absent in the mutant with the disrupted ABI4. Given that the ASMT promoter region contains several potential ABI4-binding elements, these data suggest that ASMT can be a potential target gene for ABI4. A role for ABI4 in the interactions between ABA and MT is supported by the finding that ABI4 is constitutively derepressed in the MT signaling mutants cand2 and gpa1, which exhibited elevated steady state levels of ABI4 transcripts and were not regulated by either stress or melatonin. In addition, the abi4 mutant showed increased modulations in the expression of the MT catabolic genes M2H and M3H in response to ABA treatment inferring that this transcription factor is a negative regulator of ABA-dependent changes in MT content. Furthermore, all tested mutants with impaired ABA synthesis or signaling displayed elevated steady state MT levels compared to WT, while MT treatment contributed to downregulation of key ABA synthesis and signaling genes. Collectively, our results suggest that ABA and melatonin act antagonistically modulating the expression of ABA and MT signaling and metabolism genes.
Time-Series Remote Sensing Image Classification with Active Deep Learning
Authors: Xie Gaoliang , Liu Peng , Chen Zugang , Chen Lajiao , Ma Yan , Zhao Lingjun
Published: October 2024

Deep learning methods have been widely applied to time series classification tasks. Although deep learning methods perform excellently on these tasks, they require much training data. Labeling time series data for training is very time-consuming and labor-intensive. Active learning can be used to select the most informative data for labeling in time series classification tasks to save human labeling efforts. In this paper, we propose a new active learning (AL) framework for time series data. First, a temporal classifier for pixel-level temporal classification tasks is designed. Next, We propose an effective active learning method to select informative time series samples for labeling, which combines representativeness and uncertainty. For representativeness, We use the K-shape method to cluster time series data. For uncertainty, we construct an auxiliary deep network to evaluate the uncertainty of unlabeled data. The features of the middle hidden layer with rich temporal information of the classifier will be fed into the auxiliary deep network, which is equipped with a self-attention mechanism to utilize the temporal dependencies of time series data fully. Then, we define a new loss function with the aim of improving the deep model’s performance. Finally, the proposed method in this paper was evaluated on two temporal remote-sensing image datasets. The results demonstrate a significant advantage of our method over other approaches to time series data. Code is available at https://github.com/Fighting-Golion/time_series_active_learning
Socio-cultural Construction of Menstruation in the Ghanaian Context: A Qualitative Study of the Perspectives of Parents, Teachers and Adolescent Girls
Authors: Gbogbo Sitsofe , Wuresah Israel , Gbogbo Emmanuel , Axame Wisdom Kudzo , Klutse Priscilla , Dowou Robert Kokou , Mantey Sarah Odi , Ayitey Sarah Abena Yeome , Boateng Ishmael , Nelson Paramount Eli , Kugbey Nuworza , Doku Victor Christian Korley , Hennegan Julie , Baiden Frank , Binka Fred Newton
Published: October 2024

Background: Menstruation is a natural physiological process experienced by 1.8 billion girls, and pre-menopausal women globally, and can be experienced about 300 times in a woman’s lifetime. Even though menstruation is a sign of normal female reproductive functions and marks an important transition into womanhood for adolescent girls, it is bounded by several taboos, myths, misbeliefs, or misconceptions in low-and middle-income countries including Ghana. Hence, the topic and cultural practices around menstruation are rarely discussed, and the experiences of young girls during menarche and early menstrual life remain poorly captured. This study explored the cultural construction of menstruation in the Ghanaian context.
Methods: This study was qualitative and adopted an exploratory study design. We used purposive and convenience sampling procedures for sampling five Senior High Schools and participants in the Volta Region of Ghana. 15 Focus Group Discussions (FGD) were conducted. This comprised five FGDs for female students, five FGDs for teachers, and five FGDs for parents. For each of the FGDs, 10 to 12 participants were sampled to participate in the discussion. Data were audio-recorded, transcribed, translated, and imported into MAXQDA qualitative analysis software 2022 version for analysis. Data were coded and analyzed using a thematic analysis.
Results: We found that there are a myriad of socio-cultural beliefs and practices that are associated with menstruation in Ghana. These beliefs such as menstrual blood is unclean and practices like celebration of menarche, and upholding some menstruation-related cultural/tribal taboos including household restrictions, religion, and social restrictions were identified. Our findings revealed that myths have long enveloped the facts about menstruation.
Conclusion: Cultural and social practices regarding menstruation depend on girls’ education, attitude, family environment, culture, and beliefs, pointing to the need for public health officials in the Ghanaian society to provide more culturally oriented education to the general public on menstruation and the impact of some conservative socio-cultural practices on the menstrual health of adolescents.
Advancements in Virtual Bioequivalence: Computational Methods and Regulatory Perspectives in the Pharmaceutical Industry
Authors: Alotaiq Nasser , Dermawan Doni
Published: October 2024

Background/Objectives: The rise of virtual bioequivalence studies has transformed the pharmaceutical landscape, enabling more efficient drug development processes. This systematic review aims to explore advancements in Physiologically-Based Pharmacokinetic (PBPK) modeling, its regulatory implications, and its role in achieving virtual bioequivalence, particularly for complex drug formulations. Methods: We conducted a systematic review of clinical trials using computational methods, particularly PBPK modeling, for bioequivalence assessments. Eligibility criteria are emphasized in silico modeling and pharmacokinetic simulations. Comprehensive literature searches were performed across databases such as PubMed, Scopus, and the Cochrane Library. A search strategy using key terms and Boolean operators ensured extensive coverage. We adhered to PRISMA guidelines for study selection, data extraction, and quality assessment, focusing on key characteristics, methodologies, outcomes, and regulatory perspectives from the FDA and EMA. Results: Our findings indicate that PBPK modeling significantly enhances the prediction of pharmacokinetic profiles, optimizing dosing regimens while minimizing the need for extensive clinical trials. Regulatory agencies have recognized this utility, with the FDA and EMA developing frameworks to integrate in silico methods into drug evaluations. However, challenges such as study heterogeneity and publication bias may limit the generalizability of results. Conclusions: This review highlights the critical need for standardized protocols and robust regulatory guidelines to facilitate the integration of virtual bioequivalence methodologies into pharmaceutical practices. By embracing these advancements, the industry can improve drug development efficiency and patient outcomes, paving the way for innovative therapeutic solutions. Continued research and adaptive regulatory frameworks will be essential in navigating this evolving field.